BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P16140 (517 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3J9V-F nrPDB 1057 0.0 3VR3-D nrPDB 555 e-158 3B2Q-A nrPDB 553 e-158 5Y5Y-D nrPDB 516 e-147 5BO5-A nrPDB 334 5e-92 6FKI-E nrPDB 134 7e-32 6FOC-A nrPDB 129 3e-30 5FL7-D nrPDB 127 1e-29 5IK2-D nrPDB 125 5e-29 5LQY-D nrPDB 121 6e-28 5DN6-A nrPDB 121 6e-28 5LQZ-A nrPDB 121 6e-28 2XOK-D nrPDB 120 2e-27 2XND-D nrPDB 119 3e-27 2W6I-D nrPDB 119 4e-27 5HKK-A nrPDB 118 6e-27 2DPY-A nrPDB 118 7e-27 6NJP-A nrPDB 118 8e-27 5CDF-E nrPDB 117 9e-27 4NPH-A nrPDB 116 2e-26 4Q4L-A nrPDB 116 3e-26 2R9V-A nrPDB 116 3e-26 6N2Y-A nrPDB 115 5e-26 2XND-A nrPDB 113 2e-25 4XD7-D nrPDB 113 2e-25 2W6E-A nrPDB 113 2e-25 5T4O-A nrPDB 112 3e-25 3OFN-A nrPDB 111 6e-25 5T4O-D nrPDB 109 4e-24 2OBL-A nrPDB 108 5e-24 5FL7-A nrPDB 108 8e-24 6F5D-D nrPDB 106 3e-23 3VR3-A nrPDB 105 5e-23 6FKI-F nrPDB 104 8e-23 6F5D-A nrPDB 102 4e-22 5YBH-A nrPDB 101 7e-22 6FOC-D nrPDB 97 2e-20 5BN5-A nrPDB 94 1e-19 5Y60-A nrPDB 87 2e-17 6O7W-C nrPDB 85 6e-17 3MFY-A nrPDB 82 5e-16 5N9J-W nrPDB 33 0.40 4OI0-A nrPDB 33 0.44 1HPL-A nrPDB 32 0.50 4H63-Q nrPDB 32 0.51 5EQT-A nrPDB 31 1.2 3L9S-A nrPDB 30 1.8 4N7B-A nrPDB 30 2.4 1YJS-A nrPDB 30 2.5 4TKY-A nrPDB 30 3.5 4MCU-A nrPDB 29 3.8 1X7P-A nrPDB 29 3.9 1RYX-A nrPDB 29 5.6 2B4Q-A nrPDB 29 5.9 4WUZ-A nrPDB 28 6.5 1BYO-A nrPDB 28 7.6 >3J9V-F nrPDB Length = 517 Score = 1057 bits (2734), Expect = 0.0, Method: Compositional matrix adjust. Identities = 517/517 (100%), Positives = 517/517 (100%) Query: 1 MVLSDKELFAINKKAVEQGFNVKPRLNYNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDG 60 MVLSDKELFAINKKAVEQGFNVKPRLNYNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDG Sbjct: 1 MVLSDKELFAINKKAVEQGFNVKPRLNYNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDG 60 Query: 61 TVRQGQVLEIRGDRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPI 120 TVRQGQVLEIRGDRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPI Sbjct: 61 TVRQGQVLEIRGDRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPI 120 Query: 121 DNGPKVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPH 180 DNGPKVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPH Sbjct: 121 DNGPKVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPH 180 Query: 181 NEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSL 240 NEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSL Sbjct: 181 NEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSL 240 Query: 241 FLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPG 300 FLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPG Sbjct: 241 FLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPG 300 Query: 301 RRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFV 360 RRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFV Sbjct: 301 RRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFV 360 Query: 361 DRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVV 420 DRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVV Sbjct: 361 DRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVV 420 Query: 421 GEEALSIEDKLSLEFLEKFEKTFITQGAYEDRTVFESLDQAWSLLRIYPKEMLNRISPKI 480 GEEALSIEDKLSLEFLEKFEKTFITQGAYEDRTVFESLDQAWSLLRIYPKEMLNRISPKI Sbjct: 421 GEEALSIEDKLSLEFLEKFEKTFITQGAYEDRTVFESLDQAWSLLRIYPKEMLNRISPKI 480 Query: 481 LDEFYDRARDDADEDEEDPDTRSSGKKKDASQEESLI 517 LDEFYDRARDDADEDEEDPDTRSSGKKKDASQEESLI Sbjct: 481 LDEFYDRARDDADEDEEDPDTRSSGKKKDASQEESLI 517 >3VR3-D nrPDB Length = 465 Score = 555 bits (1429), Expect = e-158, Method: Compositional matrix adjust. Identities = 258/457 (56%), Positives = 342/457 (74%), Gaps = 8/457 (1%) Query: 28 YNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGID 87 Y T+ V GPL+ +EKV +Y E++ + + +G +R+GQVLE++ D+A+VQ+FEGTSGI+ Sbjct: 12 YRTIKEVVGPLMAVEKVSGVKYEELIEVRMQNGEIRRGQVLEVQEDKAMVQIFEGTSGIN 71 Query: 88 VKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYP 147 +K ++V F G L++ VSEDM+GR+FDG GRP DNGP++ E YLDING INP AR YP Sbjct: 72 LKNSSVRFLGHPLQLGVSEDMIGRVFDGLGRPKDNGPEILPEKYLDINGEVINPIARDYP 131 Query: 148 EEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEEN 207 +E I TG+SAID +N++ RGQK+P+FS SGLPH E+AAQI RQA ++ + D Sbjct: 132 DEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKELAAQIARQATVLDSSDD-------- 183 Query: 208 FSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLA 267 F++VFAA+G+ E A FF +DF + G+++R+ +F+NLANDP IERI TPR+ALT AEYLA Sbjct: 184 FAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPAIERIATPRMALTAAEYLA 243 Query: 268 YQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNG 327 Y+ HVL I+TDM++YA+ALRE+SAAR EVPGRRGYPGY+YT+L+T++ERAGR+ G G Sbjct: 244 YEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGYLYTNLATLFERAGRIRGLKG 303 Query: 328 SITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAI 387 S+TQIPILTMP DD THPIPDLTGYITEGQI + R+L+ GI PPI+VLPSLSRL Sbjct: 304 SVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELYKSGIQPPIDVLPSLSRLKDKGT 363 Query: 388 GEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQG 447 G G TR+DH NQL+A YA GK A + V+GE ALS DK+ +F E+FE ++ QG Sbjct: 364 GAGKTREDHAATMNQLFAAYAQGKQAKELAVVLGESALSDIDKIYAKFAERFENEYVNQG 423 Query: 448 AYEDRTVFESLDQAWSLLRIYPKEMLNRISPKILDEF 484 Y +RT+ E+LD W LL + P+ L RI +LD++ Sbjct: 424 FYTNRTITETLDLGWELLAMLPRTELKRIKDDLLDKY 460 >3B2Q-A nrPDB Length = 469 Score = 553 bits (1426), Expect = e-158, Method: Compositional matrix adjust. Identities = 268/462 (58%), Positives = 343/462 (74%), Gaps = 9/462 (1%) Query: 28 YNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGID 87 Y T++ + GPL+ +EK + YNEIVN+ + DGTVR+GQVL+ D +VQVFEGT G+D Sbjct: 14 YKTITQIAGPLIFVEKTEPVGYNEIVNIKMGDGTVRRGQVLDSSADIVVVQVFEGTGGLD 73 Query: 88 VKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYP 147 K V FTGE+L++P S D+LGRI GSG P D GP++ + LDING+ +NPYAR+ P Sbjct: 74 -KDCGVIFTGETLKLPASVDLLGRILSGSGEPRDGGPRIVPDQLLDINGAAMNPYARLPP 132 Query: 148 EEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEEN 207 ++ I TG+S ID N++ RGQK+PIFSASGLPHNEIA QI RQA + G E Sbjct: 133 KDFIQTGISTIDGTNTLVRGQKLPIFSASGLPHNEIALQIARQASV--------PGSESA 184 Query: 208 FSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLA 267 F++VFAAMG+ E A++F DFE+ G+LER +FLNLA+DP +ERI+TPR+ALT AEYLA Sbjct: 185 FAVVFAAMGITNEEAQYFMSDFEKTGALERAVVFLNLADDPAVERIVTPRMALTAAEYLA 244 Query: 268 YQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNG 327 Y+ HVL ILTD+++YA+ALR++ AAR EVPGRRGYPGYMYTDL+T+YERAG V+G G Sbjct: 245 YEHGMHVLVILTDITNYAEALRQMGAARNEVPGRRGYPGYMYTDLATLYERAGIVKGAKG 304 Query: 328 SITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAI 387 S+TQIPIL+MP DDITHPIPDL+GYITEGQI V R+LH KGIYPPINVLPSLSRLM S I Sbjct: 305 SVTQIPILSMPGDDITHPIPDLSGYITEGQIVVARELHRKGIYPPINVLPSLSRLMNSGI 364 Query: 388 GEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQG 447 G G TR+DH VS+Q+YA YA G+D + A+VG+EALS D LEF + FE F+ QG Sbjct: 365 GAGKTREDHKAVSDQMYAGYAEGRDLRGLVAIVGKEALSERDTKFLEFADLFEDKFVRQG 424 Query: 448 AYEDRTVFESLDQAWSLLRIYPKEMLNRISPKILDEFYDRAR 489 E+RT+ ++L+ W +L P+ L RI K + +++ R Sbjct: 425 WNENRTIEDTLEIGWQILTHLPENQLGRIDNKYIQKYHPAHR 466 >5Y5Y-D nrPDB Length = 478 Score = 516 bits (1329), Expect = e-147, Method: Compositional matrix adjust. Identities = 254/458 (55%), Positives = 335/458 (73%), Gaps = 2/458 (0%) Query: 28 YNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGID 87 Y ++ ++GPL+ +E K Y IV++ G VR GQV+E+ + A++QVFE T+G+D Sbjct: 8 YTGITYISGPLLFVENAKDLAYGAIVDIKDGTGRVRGGQVIEVSEEYAVIQVFEETTGLD 67 Query: 88 VKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYP 147 + T+V + R+ VS++MLGR F+G G+PID P + E L I G P+NP AR P Sbjct: 68 LATTSVSLVEDVARLGVSKEMLGRRFNGIGKPIDGLPPITPEKRLPITGLPLNPVARRKP 127 Query: 148 EEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEEN 207 E+ I TG+S ID MN++ RGQK+PIFS SGLP NEIAAQI RQA VRP EE Sbjct: 128 EQFIQTGISTIDVMNTLVRGQKLPIFSGSGLPANEIAAQIARQA-TVRPDLSGEGEKEEP 186 Query: 208 FSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLA 267 F++VFAAMG+ +F Q+FE G+L R+ LFLN A+DPTIERI+TPR+ALT AEYLA Sbjct: 187 FAVVFAAMGITQRELSYFIQEFERTGALSRSVLFLNKADDPTIERILTPRMALTVAEYLA 246 Query: 268 YQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNG 327 ++ + HVL ILTDM++Y +ALRE+ AAREE+PGRRGYPGYMYTDL+TIYERAG VEG+ G Sbjct: 247 FEHDYHVLVILTDMTNYCEALREIGAAREEIPGRRGYPGYMYTDLATIYERAGVVEGKKG 306 Query: 328 SITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAI 387 S+TQIPIL+MP+DD THPIPDLTGYITEGQI + R+LH KGIYPPI+ LPSLSRLM + + Sbjct: 307 SVTQIPILSMPDDDRTHPIPDLTGYITEGQIQLSRELHRKGIYPPIDPLPSLSRLMNNGV 366 Query: 388 GEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQG 447 G+G TR+DH VS+QLY+ YA G D + A++GE+AL+ D+ L+F + FE+ FI QG Sbjct: 367 GKGKTREDHKQVSDQLYSAYANGVDIRKLVAIIGEDALTENDRRYLQFADAFERFFINQG 426 Query: 448 AYEDRTVFESLDQAWSLLRIYPKEMLNRISPKILDEFY 485 ++R++ ESL AW+LL + P+ L RIS + ++Y Sbjct: 427 Q-QNRSIEESLQIAWALLSMLPQGELKRISKDHIGKYY 463 >5BO5-A nrPDB Length = 416 Score = 334 bits (857), Expect = 5e-92, Method: Compositional matrix adjust. Identities = 188/434 (43%), Positives = 274/434 (63%), Gaps = 33/434 (7%) Query: 33 GVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGIDVKKTT 92 + PL+ +E ++ P E+++L + V+ ++A+ +F+ +G ++K+ Sbjct: 3 SIKPPLIAVE-LENPMLGEVIDLE-----ETKAIVIAAYENKALALLFDYYTG-EIKQ-- 53 Query: 93 VEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPEEMIS 152 + G + +I VSED +G IF+G G PI GPK + EDY DING INPYAR P E++ Sbjct: 54 INRQGNTYKIAVSEDYIGGIFNGFGEPI-KGPKPYPEDYRDINGLAINPYARKVPNEILY 112 Query: 153 TGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVF 212 TG+S+ID + + +GQKI IFS GLP +A QI R ++ +I+F Sbjct: 113 TGISSIDVAHPLLKGQKIAIFSPPGLPMERLALQIARNVA-------------KDKTIIF 159 Query: 213 AAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTER 272 AA+GV + + F +F ++ +++F++ A+ IE+I TPR+ALT AEYLA++ R Sbjct: 160 AAIGVPSDIYKMFIDEFINTKAIMNSAIFISKADSSPIEKIYTPRVALTLAEYLAFEKNR 219 Query: 273 HVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQI 332 VL ++ DM++YADALRE+S R+E+P RRGYP Y+YTDL++IYER+G GSIT I Sbjct: 220 DVLVLMLDMTNYADALREISTLRKEIPSRRGYPAYLYTDLASIYERSGLTS--KGSITLI 277 Query: 333 PILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMT 392 P+LTMP +DITH +PDLTGYITEGQ + + LH+K IYPPI++L SLSRL K+ GM+ Sbjct: 278 PMLTMPGNDITHVVPDLTGYITEGQYVLSQDLHSKNIYPPIDLLKSLSRLAKN----GMS 333 Query: 393 RKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQGAYEDR 452 +K H ++ L YA G +A + +VGE++LS EDK L+F E EK FI Q YE R Sbjct: 334 KK-HKKYADILIKSYAKGLEARDIATIVGEDSLSKEDKAYLKFAELVEKEFIKQDYYEYR 392 Query: 453 TV---FESLDQAWS 463 ++ FE +D S Sbjct: 393 SIEKSFEIIDSILS 406 >6FKI-E nrPDB Length = 507 Score = 134 bits (338), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 101/321 (31%), Positives = 155/321 (48%), Gaps = 19/321 (5%) Query: 91 TTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPEEM 150 ++V+ TG +IPVSE LGR+ + +PID ++ A + I +R E Sbjct: 87 SSVKATGRIAQIPVSEAYLGRVINALAKPIDGRGEITASESRLIESPAPGIMSRRSVYEP 146 Query: 151 ISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKD-VHDGHEENFS 209 + TG+ AID M + RGQ+ I RQ G D + + +N Sbjct: 147 LQTGLIAIDAMIPVGRGQRELIIGD-------------RQTGKTAVATDTILNQQGQNVI 193 Query: 210 IVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQ 269 V+ A+G + +F+E G++E T + A+ P + + P AEY Y+ Sbjct: 194 CVYVAIGQKASSVAQVVTNFQERGAMEYTIVVAETADSPATLQYLAPYTGAALAEYFMYR 253 Query: 270 TERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGR--NG 327 ERH L I D+S A A R++S PGR YPG ++ S + ERA ++ G Sbjct: 254 -ERHTLIIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSSLLGEG 312 Query: 328 SITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAI 387 S+T +PI+ D++ IP IT+GQIF+ L N GI P INV S+SR+ +A Sbjct: 313 SMTALPIVETQAGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQ 372 Query: 388 GEGMTRKDHGDVSNQLYAKYA 408 + M +K G + +L A++A Sbjct: 373 IKAM-KKVAGKLKLEL-AQFA 391 >6FOC-A nrPDB Length = 548 Score = 129 bits (324), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 91/299 (30%), Positives = 141/299 (47%), Gaps = 13/299 (4%) Query: 93 VEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPEEMIS 152 V+ TGE L +PV + LGR+ + G+PID + AE + + R E + Sbjct: 91 VKRTGEVLSVPVGDAFLGRVVNPLGQPIDGQGDIAAETRRALELQAPSVVQRQSVSEPLQ 150 Query: 153 TGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQIC---RQAGLVRPTKDVHDGHEENFS 209 TG+ AID M I RGQ+ I + R+A L K + Sbjct: 151 TGIKAIDAMTPIGRGQRQLIIGDRKTGKTAVCVDTILNQREAWLTGDPK-------QQVR 203 Query: 210 IVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQ 269 V+ A+G T K+ EE G++E T++ A+D + + P ++ Y Sbjct: 204 CVYVAIGQKGTTIASVKRALEEGGAMEYTTIVAAPASDAAGFKWLAPYTGSAIGQHWMYN 263 Query: 270 TERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRV--EGRNG 327 +HVL + D+S ADA R +S PGR +PG ++ S + ER ++ E G Sbjct: 264 G-KHVLIVFDDLSKQADAYRAISLLLRRPPGREAFPGDVFYLHSRLLERCAKLSDELGGG 322 Query: 328 SITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSA 386 S+T +PI+ +DI+ IP IT+GQ F++ L N+G+ P INV S+SR+ +A Sbjct: 323 SMTGLPIIETKANDISAFIPTNVISITDGQCFLESDLFNQGVRPAINVGVSVSRVGGAA 381 >5FL7-D nrPDB Length = 509 Score = 127 bits (318), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 102/372 (27%), Positives = 169/372 (45%), Gaps = 24/372 (6%) Query: 80 FEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPI 139 +GT G+ V+ T+V TG + IPV LGRI + G PID + A +L I+ P Sbjct: 95 MDGTEGL-VRGTSVADTGAPITIPVGRGTLGRIINVCGEPIDERGPIEATKFLPIHADPP 153 Query: 140 NPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKD 199 + E++ TG+ +D + ARG KI +F +G+ + L+ Sbjct: 154 TFAEQSTTAEVLETGIKVVDLLAPYARGGKIGLFGGAGVGKTVFIQE------LINNIAK 207 Query: 200 VHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSL-----ERTSLFLNLANDPTIERII 254 H G FS VF +G ++ +E G + + +L N+P R Sbjct: 208 AHGG----FS-VFCGVGERTREGNDLYREMKETGVINLEGESKVTLVFGQMNEPPGARAR 262 Query: 255 TPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLST 314 LT AEY + + VL + ++ + A EVSA +P GY + TD+ Sbjct: 263 VALTGLTIAEYFRDEEGQDVLLFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGA 322 Query: 315 IYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPIN 374 + ER + GS+T + + +P DD+T P P T + + R + GIYP ++ Sbjct: 323 LQERITTTQ--KGSVTSVQAVYVPADDLTDPAPATTFAHLDATTVLSRGISELGIYPAVD 380 Query: 375 VLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLE 434 L S SRL+ + ++H DV++ + K + A++G + LS +DKL++E Sbjct: 381 PLDSKSRLLDIDV----VGQEHYDVASNVQQTLQAYKSLQDIIAILGMDELSEQDKLTVE 436 Query: 435 FLEKFEKTFITQ 446 K ++ F++Q Sbjct: 437 RARKIQR-FLSQ 447 >5IK2-D nrPDB Length = 462 Score = 125 bits (313), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 115/432 (26%), Positives = 190/432 (43%), Gaps = 38/432 (8%) Query: 26 LNYNTVSGVNGPLVIL--EKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGT 83 +N + V GP+V + E + P + + P G + GD + V + Sbjct: 1 MNKGRIIQVMGPVVDIQFESGQLPDIYNAITIERPQGGTLTVEAAVHLGDNVVRCVAMAS 60 Query: 84 SGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYA 143 + V+ TG + +PV + LGR+F+ G PID +V AE+ +P Sbjct: 61 TDGLVRGLEAVDTGAPISVPVGKATLGRVFNVLGEPIDEQGEVNAEER--------HPIH 112 Query: 144 RIYPE--------EMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVR 195 R PE E++ TG+ ID + A+G KI +F +G+ + + L+ Sbjct: 113 RPAPEFEELSTADEILETGIKVIDLLAPYAKGGKIGLFGGAGVGKTVLIQE------LIN 166 Query: 196 PTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIIT 255 H G VFA +G + +++G + +TS+ N+P R+ Sbjct: 167 NVAQEHGGLS-----VFAGVGERTREGNDLYHEMKDSGVISKTSMVFGQMNEPPGARLRV 221 Query: 256 PRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTI 315 LT AEY + + VL + ++ + A EVSA +P GY + T++ + Sbjct: 222 ALTGLTMAEYFRDREGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQL 281 Query: 316 YERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINV 375 ER + GSIT I + +P DD T P P T + ++R+L GIYP ++ Sbjct: 282 QERI--TSTKKGSITSIQAIYVPADDYTDPAPATTFAHLDATTNLERKLAEMGIYPAVDP 339 Query: 376 LPSLSRLMKSA-IGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLE 434 L S SR++ A +GE R G Q+ +Y D + A++G + LS EDKL + Sbjct: 340 LASTSRILSPAVVGEEHYRVARG--VQQVLQRY---NDLQDIIAILGMDELSDEDKLIVA 394 Query: 435 FLEKFEKTFITQ 446 K ++ F++Q Sbjct: 395 RARKIQR-FLSQ 405 >5LQY-D nrPDB Length = 476 Score = 121 bits (304), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 109/404 (26%), Positives = 181/404 (44%), Gaps = 28/404 (6%) Query: 52 IVNLTLPDGTVRQGQVLEIR---GDRAIVQV-FEGTSGIDVKKTTVEFTGESLRIPVSED 107 I+N D Q VLE+ G+ A+ + +GT G+ V+ TV TG + +PV Sbjct: 30 ILNALTIDQGNNQKLVLEVAQHLGENAVRAIAMDGTEGL-VRGQTVVDTGAPISVPVGRG 88 Query: 108 MLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARG 167 LGRI + G PID + + I+ P + + E++ TG+ +D + ARG Sbjct: 89 TLGRIINVVGEPIDERGPIECKQRNPIHADPPSFVEQSTEAEVLETGIKVVDLLAPYARG 148 Query: 168 QKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQ 227 KI +F +G+ + L+ H G FS VF +G + Sbjct: 149 GKIGLFGGAGVGKTVFIQE------LINNIAKAHGG----FS-VFTGVGERTREGNDLYR 197 Query: 228 DFEENGSL-----ERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMS 282 + +E G + + +L N+P R LT AEY + + VL + ++ Sbjct: 198 EMKETGVINLEGESKVALVFGQMNEPPGARARVALTGLTIAEYFRDEEGQDVLLFVDNIF 257 Query: 283 SYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDI 342 + A EVSA +P GY + TD+ + ER R GS+T + + +P DD+ Sbjct: 258 RFTQAGSEVSALLGRIPSAVGYQPTLATDMGLLQERI--TTTRKGSVTSVQAVYVPADDL 315 Query: 343 THPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQ 402 T P P T + + R + GIYP ++ L S SRL+ ++ ++H DV+ Sbjct: 316 TDPAPATTFAHLDATTVLSRGISELGIYPAVDPLDSKSRLLDVSV----VGQEHYDVATG 371 Query: 403 LYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQ 446 + K + A++G + LS +DKL++E K ++ F++Q Sbjct: 372 VQQTLQAYKSLQDIIAILGMDELSEQDKLTVERARKIQR-FLSQ 414 >5DN6-A nrPDB Length = 511 Score = 121 bits (304), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 101/342 (29%), Positives = 163/342 (47%), Gaps = 24/342 (7%) Query: 60 GTVRQGQVLEIRGDRAIVQVFEGTSGIDVKKT-TVEFTGESLRIPVSEDMLGRIFDGSGR 118 G +R G VL + D V +F D+K+ TV+ TG + +P +++LGR+ D G Sbjct: 57 GGIR-GMVLNLETDNVGVVIFGDDR--DIKEGDTVKRTGAIVEVPAGKELLGRVVDALGN 113 Query: 119 PIDN-GPKVFAEDYL-DINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSAS 176 PID GP +E + D+ I P ++ E ++TG+ ++D M + RGQ+ I Sbjct: 114 PIDGKGPLNASERRIADVKAPGIMPRKSVH--EPMATGLKSVDAMIPVGRGQRELIIGDR 171 Query: 177 GLPHNEIAAQ-ICRQAGLVRPTKDVHDGHE----ENFSIVFAAMGVNLETARFFKQDFEE 231 IA I QA ++G E + ++ A+G T + EE Sbjct: 172 QTGKTAIALDTILNQAN--------YNGREADGMKTLHCIYVAVGQKRSTVAQLVKKLEE 223 Query: 232 NGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREV 291 G++ T++ A+DP + + P A EY L I D+S A A R++ Sbjct: 224 TGAMAYTTVVAATASDPAPMQYLAPYSATAMGEYF-RDNGMDALIIYDDLSKQAVAYRQM 282 Query: 292 SAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNG--SITQIPILTMPNDDITHPIPDL 349 S PGR YPG ++ S + ER+ ++ NG S+T +PI+ D++ IP Sbjct: 283 SLLLRRPPGREAYPGDVFYLHSRLLERSAKLNEANGAGSLTALPIIETQAGDVSAYIPTN 342 Query: 350 TGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGM 391 IT+GQIF++ +L +GI P +N S+SR+ +A + M Sbjct: 343 VISITDGQIFLETELFFQGIRPAVNTGLSVSRVGSAAQTKAM 384 >5LQZ-A nrPDB Length = 510 Score = 121 bits (304), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 89/307 (28%), Positives = 148/307 (48%), Gaps = 15/307 (4%) Query: 93 VEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYL--DINGSPINPYARIYPEEM 150 V+ TG+ + +P+ MLGR+ D G PID + A Y + I P ++ E Sbjct: 90 VKRTGKIVDVPIGPGMLGRVVDALGNPIDGKGPIEATGYAIAQLKAPGILPRRSVF--EP 147 Query: 151 ISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEEN--F 208 + TG+ A+D + I RGQ+ I +A + K +DG++E+ Sbjct: 148 MQTGLKAVDALVPIGRGQRELIIGDRQTGKTAVALDT------ILNQKRWNDGNDESKKL 201 Query: 209 SIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAY 268 V+ A+G T Q E+N +++ + + A++ + + P A AE+ Sbjct: 202 YCVYVAVGQKRSTVAQLVQTLEQNDAMKYSIVVAATASEAAPLQYLAPFTACAIAEWF-R 260 Query: 269 QTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNG- 327 +H L + D+S A A R++S PGR YPG ++ S + ERA ++ NG Sbjct: 261 DNGKHALIVYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSDANGG 320 Query: 328 -SITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSA 386 S+T +P++ D++ IP IT+GQIF++ +L KGI P INV S+SR+ +A Sbjct: 321 GSLTALPVIETQGGDVSAYIPTNVISITDGQIFLEAELFYKGIRPAINVGLSVSRVGSAA 380 Query: 387 IGEGMTR 393 + M + Sbjct: 381 QVKAMKQ 387 >2XOK-D nrPDB Length = 511 Score = 120 bits (300), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 111/427 (25%), Positives = 194/427 (45%), Gaps = 34/427 (7%) Query: 31 VSGVNGPLV--ILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIR---GDRAIVQV-FEGTS 84 V+ V G +V E+ + P + + P G + VLE+ G+ + + +GT Sbjct: 46 VTAVIGAIVDVHFEQSELPAILNALEIKTPQGKL----VLEVAQHLGENTVRTIAMDGTE 101 Query: 85 GIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYAR 144 G+ V+ V TG + +PV + LGRI + G PID + ++ I+ P + + Sbjct: 102 GL-VRGEKVLDTGGPISVPVGRETLGRIINVIGEPIDERGPIKSKLRKPIHADPPSFAEQ 160 Query: 145 IYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGH 204 E++ TG+ +D + ARG KI +F +G+ + L+ H G Sbjct: 161 STSAEILETGIKVVDLLAPYARGGKIGLFGGAGVGKTVFIQE------LINNIAKAHGG- 213 Query: 205 EENFSIVFAAMGVNLETARFFKQDFEENGSL-----ERTSLFLNLANDPTIERIITPRLA 259 FS VF +G ++ +E G + + +L N+P R Sbjct: 214 ---FS-VFTGVGERTREGNDLYREMKETGVINLEGESKVALVFGQMNEPPGARARVALTG 269 Query: 260 LTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERA 319 LT AEY + + VL + ++ + A EVSA +P GY + TD+ + ER Sbjct: 270 LTIAEYFRDEEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGLLQERI 329 Query: 320 GRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSL 379 + GS+T + + +P DD+T P P T + + R + GIYP ++ L S Sbjct: 330 --TTTKKGSVTSVQAVYVPADDLTDPAPATTFAHLDATTVLSRGISELGIYPAVDPLDSK 387 Query: 380 SRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKF 439 SRL+ +A+ ++H DV++++ K + A++G + LS +DKL++E K Sbjct: 388 SRLLDAAV----VGQEHYDVASKVQETLQTYKSLQDIIAILGMDELSEQDKLTVERARKI 443 Query: 440 EKTFITQ 446 ++ F++Q Sbjct: 444 QR-FLSQ 449 >2XND-D nrPDB Length = 467 Score = 119 bits (299), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 100/373 (26%), Positives = 165/373 (44%), Gaps = 25/373 (6%) Query: 80 FEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPI 139 +GT G+ V+ V +G +RIPV + LGRI + G PID + + + I+ Sbjct: 55 MDGTEGL-VRGQKVLDSGAPIRIPVGPETLGRIMNVIGEPIDERGPIKTKQFAAIHAEAP 113 Query: 140 NPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKD 199 +E++ TG+ +D + A+G KI +F +G+ + + L+ Sbjct: 114 EFVEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIME------LINNVAK 167 Query: 200 VHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSL------ERTSLFLNLANDPTIERI 253 H G+ VFA +G + E+G + + +L N+P R Sbjct: 168 AHGGYS-----VFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARA 222 Query: 254 ITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLS 313 LT AEY Q + VL + ++ + A EVSA +P GY + TD+ Sbjct: 223 RVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMG 282 Query: 314 TIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPI 373 T+ ER + GSIT + + +P DD+T P P T + + R + GIYP + Sbjct: 283 TMQERITTT--KKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAV 340 Query: 374 NVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSL 433 + L S SR+M I +H DV+ + K + A++G + LS EDKL++ Sbjct: 341 DPLDSTSRIMDPNI----VGSEHYDVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTV 396 Query: 434 EFLEKFEKTFITQ 446 K ++ F++Q Sbjct: 397 SRARKIQR-FLSQ 408 >2W6I-D nrPDB Length = 528 Score = 119 bits (297), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 100/373 (26%), Positives = 165/373 (44%), Gaps = 25/373 (6%) Query: 80 FEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPI 139 +GT G+ V+ V +G +RIPV + LGRI + G PID + + + I+ Sbjct: 113 MDGTEGL-VRGQKVLDSGAPIRIPVGPETLGRIMNVIGEPIDERGPIKTKQFAAIHAEAP 171 Query: 140 NPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKD 199 +E++ TG+ +D + A+G KI +F +G+ + + L+ Sbjct: 172 EFVEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIME------LINNVAK 225 Query: 200 VHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSL------ERTSLFLNLANDPTIERI 253 H G+ VFA +G + E+G + + +L N+P R Sbjct: 226 AHGGYS-----VFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARA 280 Query: 254 ITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLS 313 LT AEY Q + VL + ++ + A EVSA +P GY + TD+ Sbjct: 281 RVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMG 340 Query: 314 TIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPI 373 T+ ER + GSIT + + +P DD+T P P T + + R + GIYP + Sbjct: 341 TMQERI--TTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAV 398 Query: 374 NVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSL 433 + L S SR+M I +H DV+ + K + A++G + LS EDKL++ Sbjct: 399 DPLDSTSRIMDPNI----VGSEHYDVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTV 454 Query: 434 EFLEKFEKTFITQ 446 K ++ F++Q Sbjct: 455 SRARKIQR-FLSQ 466 >5HKK-A nrPDB Length = 502 Score = 118 bits (296), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 87/306 (28%), Positives = 140/306 (45%), Gaps = 17/306 (5%) Query: 91 TTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPEEM 150 T V+ TG + +PV E +LGR+ + G+P+D + +Y I R E Sbjct: 86 TQVKRTGRIMEVPVGEALLGRVVNPLGQPLDGRGPIETAEYRPIESPAPGVMDRKSVHEP 145 Query: 151 ISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQ-ICRQAGLVRPTKDVHDGHEENFS 209 + TG+ AID+M I RGQ+ I IA I Q G ++ Sbjct: 146 LQTGIKAIDSMIPIGRGQRELIIGDRQTGKTTIAIDTIINQKG-------------QDVI 192 Query: 210 IVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQ 269 ++ A+G T + ++ +L+ T + A++P + P EY Y+ Sbjct: 193 CIYVAIGQKQSTVAGVVETLRQHDALDYTIVVTASASEPAPLLYLAPYAGCAMGEYFMYK 252 Query: 270 TERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRV--EGRNG 327 +H L + D+S A A RE+S PGR YPG ++ S + ERA ++ E G Sbjct: 253 G-KHALVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDEKGGG 311 Query: 328 SITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAI 387 S+T +P + D++ IP IT+GQIF++ L G+ P +NV S+SR+ +A Sbjct: 312 SLTALPFIETQAGDVSAYIPTNVISITDGQIFLESDLFYSGVRPAVNVGISVSRVGGAAQ 371 Query: 388 GEGMTR 393 + M + Sbjct: 372 IKAMKK 377 >2DPY-A nrPDB Length = 438 Score = 118 bits (295), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 113/383 (29%), Positives = 175/383 (45%), Gaps = 51/383 (13%) Query: 101 RIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDING---SPINPYARIYPEEMISTGVSA 157 ++P+ +LGR+ DG G+P+D P A D L+ P NP R E ++ TGV A Sbjct: 91 QLPLGPALLGRVLDGGGKPLDGLP---APDTLETGALITPPFNPLQRTPIEHVLDTGVRA 147 Query: 158 IDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGV 217 I+ + ++ RGQ++ +F+ SG+ + + + R DV IV +G Sbjct: 148 INALLTVGRGQRMGLFAGSGVGKSVLLGMMARYT-----RADV---------IVVGLIG- 192 Query: 218 NLETARFFKQDFEEN--GSLERT-SLFLNLANDPTIERIITPRLALTTAEYLAYQTE--- 271 E R K DF EN G R S+ + D ++P L + A Y E Sbjct: 193 --ERGREVK-DFIENILGPDGRARSVVIAAPAD------VSPLLRMQGAAYATRIAEDFR 243 Query: 272 ---RHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGS 328 +HVL I+ ++ YA A RE++ A E P +GYP ++ L + ERAG GS Sbjct: 244 DRGQHVLLIMDSLTRYAMAQREIALAIGEPPATKGYPPSVFAKLPALVERAGNGIHGGGS 303 Query: 329 ITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIG 388 IT + DD PI D I +G I + R+L G YP I++ S+SR M + I Sbjct: 304 ITAFYTVLTEGDDQQDPIADSARAILDGHIVLSRRLAEAGHYPAIDIEASISRAMTALI- 362 Query: 389 EGMTRKDHGDVS--NQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQ 446 T + + V QL + + +D ++ A ++ ++L + E F+ Q Sbjct: 363 ---TEQHYARVRLFKQLLSSFQRNRDLVSVGAYAKGSDPMLDKAITL--WPQLE-AFLQQ 416 Query: 447 GAYEDRTVFESLDQAWSLLRIYP 469 G +E R +E QA L I+P Sbjct: 417 GIFE-RADWEDSLQALDL--IFP 436 >6NJP-A nrPDB Length = 449 Score = 118 bits (295), Expect = 8e-27, Method: Compositional matrix adjust. Identities = 106/397 (26%), Positives = 182/397 (45%), Gaps = 40/397 (10%) Query: 63 RQGQVLEIRGDRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDN 122 R +V+ I D + FE SG+ + + + G+ +I V + +LGR+ DG GRP+++ Sbjct: 69 RLAEVIAIDEDEVFLLPFEHVSGMYCGQW-LSYQGDEFKIRVGDALLGRLIDGIGRPMES 127 Query: 123 GPKVFAEDYL----DINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGL 178 YL + P +P R ++ GV AID + + GQ+I IF+ SG+ Sbjct: 128 N---IVAPYLPFERSLYAEPPDPLLRQVIDQPFILGVRAIDGLLTCGIGQRIGIFAGSGV 184 Query: 179 PHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERT 238 + + IC A + D+ IV A +G F ++ +L + Sbjct: 185 GKSTLLGMICNGA-----SADI---------IVLALIGERGREVNEFLALLPQS-TLSKC 229 Query: 239 SLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEV 298 L + ++ P +ER+ A T AEY Q ++VL ++ ++ YA A R+V A E Sbjct: 230 VLVVTTSDRPALERMKAAFTATTIAEYFRDQG-KNVLLMMDSVTRYARAARDVGLASGEP 288 Query: 299 PGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQI 358 R G+P +++ L + ERAG GSIT I + + +D++ PI D I +G I Sbjct: 289 DVRGGFPPSVFSSLPKLLERAG--PAPKGSITAIYTVLLESDNVNDPIGDEVRSILDGHI 346 Query: 359 FVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYA------------K 406 + R+L + +P I++ S SR+M + + R +L A + Sbjct: 347 VLTRELAEENHFPAIDIGLSASRVMHNVVTSEHLRA--AAECKKLIATYKNVELLIRIGE 404 Query: 407 YAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTF 443 Y +G+D A KA+ + + + S + + +EKT Sbjct: 405 YTMGQDPEADKAIKNRKLIQNFIQQSTKDISSYEKTI 441 >5CDF-E nrPDB Length = 474 Score = 117 bits (294), Expect = 9e-27, Method: Compositional matrix adjust. Identities = 101/374 (27%), Positives = 167/374 (44%), Gaps = 26/374 (6%) Query: 80 FEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPI 139 + T G+ V+ V+ TG + +PV + LGRI + G P+D G V A I+ Sbjct: 58 MDATEGL-VRGLPVKDTGGPIMVPVGDATLGRILNVVGEPVDEGGPVEATQTRAIHQQAP 116 Query: 140 NPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKD 199 + A+ E++ TG+ ID + ++G KI +F +G+ + + L+ Sbjct: 117 DFAAQATASEILVTGIKVIDLLAPYSKGGKIGLFGGAGVGKTVLIME------LINNIAK 170 Query: 200 VHDGHEENFSIVFAAMGVNLETARFFKQDFEENG-------SLERTSLFLNLANDPTIER 252 VH G+ VFA +G + E+G S + +L N+P R Sbjct: 171 VHSGYS-----VFAGVGERTREGNDLYHEMVESGVIKPDDLSKSQVALVYGQMNEPPGAR 225 Query: 253 IITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDL 312 + LT AE T VL + ++ + A EVSA +P GY + TD+ Sbjct: 226 MRVALTGLTVAEQFRDATGTDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDM 285 Query: 313 STIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPP 372 + ER +NGSIT I + +P DD+T P P T + + R + GIYP Sbjct: 286 GAMQERI--TSTKNGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRAISELGIYPA 343 Query: 373 INVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLS 432 ++ L S SR++ A+ ++H V+ + K + A++G + LS EDKL+ Sbjct: 344 VDPLDSNSRILDPAV----VGEEHYQVARDVQGILQKYKSLQDIIAILGMDELSEEDKLT 399 Query: 433 LEFLEKFEKTFITQ 446 + K ++ F++Q Sbjct: 400 VARARKIQR-FLSQ 412 >4NPH-A nrPDB Length = 351 Score = 116 bits (291), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 85/286 (29%), Positives = 138/286 (48%), Gaps = 22/286 (7%) Query: 100 LRIPVSEDMLGRIFDGSGRPIDNG--PKVFAEDYLDINGSPINPYARIYPEEMISTGVSA 157 +++PV E +LGR+ DG GRP+D P V +DY + P R + + TG+ A Sbjct: 1 MQVPVGEALLGRVIDGFGRPLDGRELPDVCWKDY---DAMPPPAMVRQPITQPLMTGIRA 57 Query: 158 IDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGV 217 ID++ + GQ++ IFSA G+ + + A +C P D S V +G Sbjct: 58 IDSVATCGEGQRVGIFSAPGVGKSTLLAMLCNA-----PDAD---------SNVLVLIGE 103 Query: 218 NLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTI 277 R F + +R + + ++ P +ER+ +A T AE+ +R VL + Sbjct: 104 RGREVREFIDFTLSEETRKRCVIVVATSDRPALERVRALFVATTIAEFFRDNGKRVVL-L 162 Query: 278 LTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTM 337 ++ YA A RE++ A E YP +++ L + ER G G GSIT + + Sbjct: 163 ADSLTRYARAAREIALAAGETAVSGEYPPGVFSALPRLLERTGM--GEKGSITAFYTVLV 220 Query: 338 PNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLM 383 DD+ P+ D + +G I + R+L +G YP I+VL +LSR+ Sbjct: 221 EGDDMNEPLADEVRSLLDGHIVLSRRLAERGHYPAIDVLATLSRVF 266 >4Q4L-A nrPDB Length = 485 Score = 116 bits (290), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 105/407 (25%), Positives = 189/407 (46%), Gaps = 25/407 (6%) Query: 44 VKFPRYN--EIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGIDVKKTTVEFTGESLR 101 V+FPR + +I + + +G+ +V + GD + + G S + V+ TG + Sbjct: 42 VEFPRESMPKIYDALILEGSELTLEVQQQLGDGVVRTICLGASDGLRRGVVVKNTGNPIS 101 Query: 102 IPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPE-EMISTGVSAIDT 160 +PV + LGRI D GRPID + +E+ I+ + + P E++ TG+ ID Sbjct: 102 VPVGKPTLGRIMDVLGRPIDEAGPIESENKRSIH-QKAPAFDELSPSTELLETGIKVIDL 160 Query: 161 MNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLE 220 + A+G K+ +F +G+ + L+ H G+ VFA +G Sbjct: 161 ICPFAKGGKVGLFGGAGV------GKTVNMMELINNIAKEHGGYS-----VFAGVGERTR 209 Query: 221 TARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTD 280 F + +++ L++ +L N+P R+ LT AE+ + VL + + Sbjct: 210 EGNDFYHEMKDSNVLDKVALVYGQMNEPPGNRLRVALTGLTMAEHFRDEG-LDVLFFVDN 268 Query: 281 MSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPND 340 + + A EVSA +P GY + ++ + ER + GSIT + + +P D Sbjct: 269 IYRFTLAGTEVSALLGRMPSAVGYQPTLAEEMGKLQERI--TSTKKGSITSVQAVYVPAD 326 Query: 341 DITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMK-SAIGEGMTRKDHGDV 399 D+T P P T + + + R + + GIYP ++ L S SR + + IGE +H + Sbjct: 327 DLTDPSPATTFGHLDATVVLSRDIASLGIYPAVDPLDSTSRQIDPNVIGE-----EHYSI 381 Query: 400 SNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQ 446 + ++ K+ + A++G + LS EDKLS+ K ++ F++Q Sbjct: 382 TRRVQQTLQRYKELRDIIAILGMDELSPEDKLSVARARKIQR-FLSQ 427 >2R9V-A nrPDB Length = 515 Score = 116 bits (290), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 90/304 (29%), Positives = 142/304 (46%), Gaps = 18/304 (5%) Query: 87 DVKK-TTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARI 145 D+K+ TV + +PV E++LGR+ + G P+D + A+++ I R Sbjct: 94 DIKEGHTVRRLKRIIEVPVGEELLGRVVNPLGEPLDGKGPINAKNFRPIEIKAPGVIYRK 153 Query: 146 YPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQ-ICRQAGLVRPTKDVHDGH 204 + + TG+ AID+M I RGQ+ I IA I Q G Sbjct: 154 PVDTPLQTGIKAIDSMIPIGRGQRELIIGDRQTGKTAIAIDTIINQKG------------ 201 Query: 205 EENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAE 264 + ++ A+G + G++E T++ + A+DP + I P E Sbjct: 202 -QGVYCIYVAIGQKKSAIARIIDKLRQYGAMEYTTVVVASASDPASLQYIAPYAGCAMGE 260 Query: 265 YLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEG 324 Y AY + R L + D+S +A A R++S PGR YPG ++ S + ERA R+ Sbjct: 261 YFAY-SGRDALVVYDDLSKHAVAYRQLSLLMRRPPGREAYPGDIFYLHSRLLERAVRLND 319 Query: 325 R--NGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRL 382 + GS+T +PI+ +DI+ IP IT+GQI+++ L G P INV S+SR+ Sbjct: 320 KLGGGSLTALPIVETQANDISAYIPTNVISITDGQIYLEPGLFYAGQRPAINVGLSVSRV 379 Query: 383 MKSA 386 SA Sbjct: 380 GGSA 383 >6N2Y-A nrPDB Length = 502 Score = 115 bits (288), Expect = 5e-26, Method: Compositional matrix adjust. Identities = 87/304 (28%), Positives = 138/304 (45%), Gaps = 17/304 (5%) Query: 93 VEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPEEMIS 152 V TG + +PV E ++GR+ + G+P+D V + I R E + Sbjct: 88 VRRTGRIMEVPVGEALIGRVVNPLGQPVDGLGPVETTETRPIESPAPGVMDRRSVHEPLQ 147 Query: 153 TGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKD-VHDGHEENFSIV 211 TG+ AID + I RGQ+ I RQ G D + + ++N + Sbjct: 148 TGIKAIDALVPIGRGQRELIIG-------------DRQTGKTSVAIDTIINQKDQNMISI 194 Query: 212 FAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTE 271 + A+G T R + ++G+L+ T + A+ P + P + EY Y+ Sbjct: 195 YVAIGQKESTVRTVVETLRKHGALDYTIVVTASASQPAPLLFLAPYAGVAMGEYFMYKG- 253 Query: 272 RHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGR--NGSI 329 +HVL + D+S A A RE+S PGR YPG ++ S + ERA ++ GS+ Sbjct: 254 KHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDIFYLHSRLLERAAKLSDAKGGGSL 313 Query: 330 TQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGE 389 T +P + DI+ IP IT+GQIF+ L G+ P IN S+SR+ +A + Sbjct: 314 TALPFVETQAGDISAYIPTNVISITDGQIFLQSDLFFSGVRPAINAGLSVSRVGGAAQIK 373 Query: 390 GMTR 393 M + Sbjct: 374 AMKK 377 >2XND-A nrPDB Length = 492 Score = 113 bits (282), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 116/430 (26%), Positives = 193/430 (44%), Gaps = 34/430 (7%) Query: 64 QGQVLEIRGDRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDN- 122 +G L + D V VF G + + V+ TG + +PV E++LGR+ D G ID Sbjct: 42 KGMSLNLEPDNVGVVVF-GNDKLIKEGDIVKRTGAIVDVPVGEELLGRVVDALGNAIDGK 100 Query: 123 GP-KVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHN 181 GP A + + I P RI E + TG+ A+D++ I RGQ+ I Sbjct: 101 GPIGSKARRRVGLKAPGIIP--RISVREPMQTGIKAVDSLVPIGRGQRELIIGDRQTGKT 158 Query: 182 EIAAQ-ICRQAGLVRPTKDVHDGHEEN--FSIVFAAMGVNLETARFFKQDFEENGSLERT 238 IA I Q K +DG +E ++ A+G T + + +++ T Sbjct: 159 SIAIDTIINQ-------KRFNDGTDEKKKLYCIYVAIGQKRSTVAQLVKRLTDADAMKYT 211 Query: 239 SLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEV 298 + A+D + + P + EY +H L I D+S A A R++S Sbjct: 212 IVVSATASDAAPLQYLAPYSGCSMGEYF-RDNGKHALIIYDDLSKQAVAYRQMSLLLRRP 270 Query: 299 PGRRGYPGYMYTDLSTIYERAGRVEGR--NGSITQIPILTMPNDDITHPIPDLTGYITEG 356 PGR YPG ++ S + ERA ++ GS+T +P++ D++ IP IT+G Sbjct: 271 PGREAYPGDVFYLHSRLLERAAKMNDAFGGGSLTALPVIETQAGDVSAYIPTNVISITDG 330 Query: 357 QIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAM 416 QIF++ +L KGI P INV S+SR+ +A M + V+ + + A ++ AA Sbjct: 331 QIFLETELFYKGIRPAINVGLSVSRVGSAAQTRAMKQ-----VAGTMKLELAQYREVAAF 385 Query: 417 KAVVGEEALSIEDKLSLEFLEKFEKT--FITQGAYEDRTVFESLDQAWSLLRIYPKEMLN 474 A G + D + + L + + + QG Y + E + ++ +R Y L+ Sbjct: 386 -AQFGSDL----DAATQQLLSRGVRLTELLKQGQYSPMAIEEQVAVIYAGVRGY----LD 436 Query: 475 RISPKILDEF 484 ++ P + +F Sbjct: 437 KLEPSKITKF 446 >4XD7-D nrPDB Length = 483 Score = 113 bits (282), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 92/353 (26%), Positives = 163/353 (46%), Gaps = 21/353 (5%) Query: 96 TGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPE-EMISTG 154 TG + +PV E LGR+F+ G PID + A+ D P + + E E++ TG Sbjct: 89 TGAPISVPVGEVTLGRVFNVLGEPIDLEGDIPADARRDPIHRPAPKFEELATEVEILETG 148 Query: 155 VSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSI-VFA 213 + +D + +G KI +F +G+ + ++ +H+ +E+ I VFA Sbjct: 149 IKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQEL------------IHNIAQEHGGISVFA 196 Query: 214 AMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERH 273 +G + +++G + +T++ N+P R+ LT AEY + + Sbjct: 197 GVGERTREGNDLYHEMKDSGVISKTAMVFGQMNEPPGARMRVALTGLTMAEYFRDEQGQD 256 Query: 274 VLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIP 333 VL + ++ + A EVSA +P GY + T++ + ER GSIT I Sbjct: 257 VLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERI--TSTAKGSITSIQ 314 Query: 334 ILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTR 393 + +P DD T P P T + ++R+L GIYP ++ L S SR A+ + Sbjct: 315 AIYVPADDYTDPAPATTFSHLDATTNLERKLAEMGIYPAVDPLASTSR----ALAPEIVG 370 Query: 394 KDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQ 446 ++H V+ ++ K+ + A++G + LS EDKL + + + F++Q Sbjct: 371 EEHYQVARKVQQTLQRYKELQDIIAILGMDELSDEDKLVVHRARRIQ-FFLSQ 422 >2W6E-A nrPDB Length = 553 Score = 113 bits (282), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 116/430 (26%), Positives = 193/430 (44%), Gaps = 34/430 (7%) Query: 64 QGQVLEIRGDRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDN- 122 +G L + D V VF G + + V+ TG + +PV E++LGR+ D G ID Sbjct: 103 KGMSLNLEPDNVGVVVF-GNDKLIKEGDIVKRTGAIVDVPVGEELLGRVVDALGNAIDGK 161 Query: 123 GP-KVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHN 181 GP A + + I P RI E + TG+ A+D++ I RGQ+ I Sbjct: 162 GPIGSKARRRVGLKAPGIIP--RISVREPMQTGIKAVDSLVPIGRGQRELIIGDRQTGKT 219 Query: 182 EIAA-QICRQAGLVRPTKDVHDGHEEN--FSIVFAAMGVNLETARFFKQDFEENGSLERT 238 IA I Q K +DG +E ++ A+G T + + +++ T Sbjct: 220 SIAIDTIINQ-------KRFNDGTDEKKKLYCIYVAIGQKRSTVAQLVKRLTDADAMKYT 272 Query: 239 SLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEV 298 + A+D + + P + EY +H L I D+S A A R++S Sbjct: 273 IVVSATASDAAPLQYLAPYSGCSMGEYF-RDNGKHALIIYDDLSKQAVAYRQMSLLLRRP 331 Query: 299 PGRRGYPGYMYTDLSTIYERAGRVEGR--NGSITQIPILTMPNDDITHPIPDLTGYITEG 356 PGR YPG ++ S + ERA ++ GS+T +P++ D++ IP IT+G Sbjct: 332 PGREAYPGDVFYLHSRLLERAAKMNDAFGGGSLTALPVIETQAGDVSAYIPTNVISITDG 391 Query: 357 QIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAM 416 QIF++ +L KGI P INV S+SR+ +A M + V+ + + A ++ AA Sbjct: 392 QIFLETELFYKGIRPAINVGLSVSRVGSAAQTRAMKQ-----VAGTMKLELAQYREVAAF 446 Query: 417 KAVVGEEALSIEDKLSLEFLEKFEKT--FITQGAYEDRTVFESLDQAWSLLRIYPKEMLN 474 A G + D + + L + + + QG Y + E + ++ +R Y L+ Sbjct: 447 -AQFGSDL----DAATQQLLSRGVRLTELLKQGQYSPMAIEEQVAVIYAGVRGY----LD 497 Query: 475 RISPKILDEF 484 ++ P + +F Sbjct: 498 KLEPSKITKF 507 >5T4O-A nrPDB Length = 513 Score = 112 bits (280), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 95/370 (25%), Positives = 161/370 (43%), Gaps = 46/370 (12%) Query: 49 YNEIVNLTLPDGTVR--------QGQVLEIRGDR----------AIVQVFEGTSGIDVKK 90 +NE +++ DG +R QG+++ + G+R ++ V G + Sbjct: 26 HNEGTIVSVSDGVIRIHGLADAMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEG 85 Query: 91 TTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPEEM 150 V+ TG L +PV +LGR+ + G PID + + + + R ++ Sbjct: 86 MKVKATGRILEVPVGRGLLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQP 145 Query: 151 ISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKD-VHDGHEENFS 209 + TG A+D+M I RGQ+ I RQ G D + + + Sbjct: 146 VQTGYKAVDSMIPIGRGQRELIIG-------------DRQTGKTALAIDAIINQRDSGIK 192 Query: 210 IVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQ 269 ++ A+G T + EE+G+L T + + A++ + + P EY + Sbjct: 193 AIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPYAGAAMGEYFRDR 252 Query: 270 TERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRV------- 322 E L I D+S A A R++S PGR +PG ++ S + ERA RV Sbjct: 253 GE-DALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEA 311 Query: 323 ------EGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVL 376 +G+ GS+T +PI+ D++ +P IT+GQIF++ L N GI P +N Sbjct: 312 FTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPG 371 Query: 377 PSLSRLMKSA 386 S+SR+ +A Sbjct: 372 ISVSRVGGAA 381 >3OFN-A nrPDB Length = 510 Score = 111 bits (278), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 84/300 (28%), Positives = 143/300 (47%), Gaps = 15/300 (5%) Query: 93 VEFTGESLRIPVSEDMLGRIFDGSGRPIDN-GP-KVFAEDYLDINGSPINPYARIYPEEM 150 V+ TG + +PV +LGR+ D G PID GP + I P ++ E Sbjct: 90 VKRTGNIVDVPVGPGLLGRVVDALGNPIDGKGPIDAAGRSRAQVKAPGILPRRSVH--EP 147 Query: 151 ISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEEN--F 208 + TG+ A+D + I RGQ+ I +A + K ++G +E+ Sbjct: 148 VQTGLKAVDALVPIGRGQRELIIGDRQTGKTAVALDT------ILNQKRWNNGSDESKKL 201 Query: 209 SIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAY 268 V+ A+G T Q E++ +++ + + A++ + + P A + E+ Sbjct: 202 YCVYVAVGQKRSTVAQLVQTLEQHDAMKYSIIVAATASEAAPLQYLAPFTAASIGEWF-R 260 Query: 269 QTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGR--N 326 +H L + D+S A A R++S PGR YPG ++ S + ERA ++ + + Sbjct: 261 DNGKHALIVYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSEKEGS 320 Query: 327 GSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSA 386 GS+T +P++ D++ IP IT+GQIF++ +L KGI P INV S+SR+ +A Sbjct: 321 GSLTALPVIETQGGDVSAYIPTNVISITDGQIFLEAELFYKGIRPAINVGLSVSRVGSAA 380 >5T4O-D nrPDB Length = 471 Score = 109 bits (272), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 93/363 (25%), Positives = 166/363 (45%), Gaps = 26/363 (7%) Query: 85 GIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYAR 144 G+DVK + +PV + LGRI + G P+D ++ E+ I+ + + Sbjct: 77 GLDVKDLE-----HPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEEL 131 Query: 145 IYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGH 204 +E++ TG+ ID M A+G K+ +F +G+ + L+R H G+ Sbjct: 132 SNSQELLETGIKVIDLMAPFAKGGKVGLFGGAGV------GKTVNMMELIRNIAIEHSGY 185 Query: 205 EENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAE 264 VFA +G F + ++ +++ SL N+P R+ LT AE Sbjct: 186 S-----VFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAE 240 Query: 265 YLAYQTE-RHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVE 323 ++ E R VL + ++ Y A EVSA +P GY + ++ + ER Sbjct: 241 --KFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERI--TS 296 Query: 324 GRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLM 383 + GSIT + + +P DD+T P P T + + + RQ+ + GIYP ++ L S SR + Sbjct: 297 TKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQL 356 Query: 384 KSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTF 443 + ++H D + + + ++ + A++G + LS EDKL + K ++ F Sbjct: 357 DPLV----VGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQR-F 411 Query: 444 ITQ 446 ++Q Sbjct: 412 LSQ 414 >2OBL-A nrPDB Length = 347 Score = 108 bits (270), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 98/361 (27%), Positives = 166/361 (45%), Gaps = 39/361 (10%) Query: 99 SLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYL----DINGSPINPYARIYPEEMISTG 154 S +I V + +LGR+ DG GRP+++ YL + P +P R ++ G Sbjct: 2 SHKIRVGDALLGRLIDGIGRPMESN---IVAPYLPFERSLYAEPPDPLLRQVIDQPFILG 58 Query: 155 VSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAA 214 V AID + + GQ+I IF+ SG+ + + IC A + D+ IV A Sbjct: 59 VRAIDGLLTCGIGQRIGIFAGSGVGKSTLLGMICNGA-----SADI---------IVLAL 104 Query: 215 MGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHV 274 +G F ++ +L + L + ++ P +ER+ A T AEY Q ++V Sbjct: 105 IGERGREVNEFLALLPQS-TLSKCVLVVTTSDRPALERMKAAFTATTIAEYFRDQG-KNV 162 Query: 275 LTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPI 334 L ++ ++ YA A R+V A E R G+P +++ L + ERAG GSIT I Sbjct: 163 LLMMDSVTRYARAARDVGLASGEPDVRGGFPPSVFSSLPKLLERAG--PAPKGSITAIYT 220 Query: 335 LTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRK 394 + + +D++ PI D I +G I + R+L + +P I++ S SR+M + + R Sbjct: 221 VLLESDNVNDPIGDEVRSILDGHIVLTRELAEENHFPAIDIGLSASRVMHNVVTSEHLRA 280 Query: 395 DHGDVSNQLYA------------KYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKT 442 +L A +Y +G+D A KA+ + + + S + + +EKT Sbjct: 281 --AAECKKLIATYKNPELLIRIGEYTMGQDPEADKAIKNRKLIQNFIQQSTKDISSYEKT 338 Query: 443 F 443 Sbjct: 339 I 339 >5FL7-A nrPDB Length = 536 Score = 108 bits (269), Expect = 8e-24, Method: Compositional matrix adjust. Identities = 82/297 (27%), Positives = 134/297 (45%), Gaps = 7/297 (2%) Query: 92 TVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPEEMI 151 TV+ +G + +PV +LGR+ D G PID + E + R E + Sbjct: 113 TVKRSGSIVDVPVGPALLGRVVDALGNPIDGKGPIETEFRIRAQVKAPGILPRTSVNEPM 172 Query: 152 STGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIV 211 TG+ A+D + I RGQ+ I +IA L + + ++ V Sbjct: 173 QTGLKAVDALVPIGRGQRELIIGDRQTGKTQIAIDTI----LNQKRWNYGQDEKKKLYCV 228 Query: 212 FAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTE 271 + A+G T Q E + +L+ + + A++ + + P E+ Sbjct: 229 YVAVGQKRSTVAQLVQTLEHHDALKYSIIVAATASEAAPLQYLAPFTGTAMGEWF-RDNG 287 Query: 272 RHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGR--NGSI 329 + L + D+S A A R++S PGR YPG ++ S + ERA ++ R GS+ Sbjct: 288 KGALIVFDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNEREGGGSL 347 Query: 330 TQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSA 386 T +PI+ D++ IP IT+GQIF++ +L KGI P INV S+SR+ +A Sbjct: 348 TALPIIETQGGDVSAYIPTNVISITDGQIFLEAELFYKGIRPAINVGLSVSRVGSAA 404 >6F5D-D nrPDB Length = 498 Score = 106 bits (264), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 101/365 (27%), Positives = 161/365 (44%), Gaps = 29/365 (7%) Query: 90 KTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPEE 149 K V TG ++ +PV + LGRIF+ G ID V + + I+ + + Sbjct: 78 KAKVVSTGGNISVPVGRETLGRIFNVLGDAIDQRGPVGEKLRMPIHAVAPKLADQAAEDA 137 Query: 150 MISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFS 209 +++TG+ ID + +G KI +F +G+ I ++ +V GH FS Sbjct: 138 VLTTGIKVIDLILPYCKGGKIGLFGGAGVGKTVIIMELI---------NNVAKGHG-GFS 187 Query: 210 IVFAAMGVNLETARFFKQDFEENGSLE-----RTSLFLNLANDPTIERIITPRLALTTAE 264 VFA +G + ++ ++ + L N+P R + ALT AE Sbjct: 188 -VFAGVGERTREGTDLYLEMMQSKVIDLKGESKCVLVYGQMNEPPGARARVAQSALTMAE 246 Query: 265 YLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEG 324 Y + VL + ++ + A EVSA +P GY + DL + ER Sbjct: 247 YFRDVEGQDVLLFIDNIFRFTQANSEVSALLGRIPAAVGYQPTLAEDLGQLQERI--TST 304 Query: 325 RNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMK 384 GSIT + + +P DDIT P P T + +DR + GIYP +N L SR+M Sbjct: 305 TKGSITSVQAVYVPADDITDPAPATTFSHLDATTVLDRAVAESGIYPAVNPLECASRIMD 364 Query: 385 SAIGEGMTRKDHGDVSN---QLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEK 441 + DH +V+ Q+ KY ++ + AV+G + LS EDKL ++ K K Sbjct: 365 PDV----ISVDHYNVAQDVVQMLTKY---RELQDIIAVLGIDELSEEDKLIVDRARKLVK 417 Query: 442 TFITQ 446 F++Q Sbjct: 418 -FLSQ 421 >3VR3-A nrPDB Length = 600 Score = 105 bits (262), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 74/242 (30%), Positives = 128/242 (52%), Gaps = 12/242 (4%) Query: 235 LERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSS-YADALREVSA 293 +ERT L N +N P R + +T AEY ++ + + I+ D +S +A+ALRE+S Sbjct: 293 MERTVLIANTSNMPVAAREASIYTGITIAEY--FRDMGYDVAIMADSTSRWAEALREMSG 350 Query: 294 AREEVPGRRGYPGYMYTDLSTIYERAGRV-----EGRNGSITQIPILTMPNDDITHPIPD 348 EE+PG GYP Y+ + L+ YER+GRV + R GSIT I ++ DI+ P+ Sbjct: 351 RLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSDQREGSITAISAVSPSGGDISEPVTQ 410 Query: 349 LTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYA 408 T + + +D L K +P IN + S S L + +G M + D S+ + Sbjct: 411 NTLRVVKVFWGLDSSLAQKRHFPSINWIQSYS-LYSTEVGRYMDQILQQDWSDMVTEGMR 469 Query: 409 IGKDAAAMKAV---VGEEALSIEDKLSLEFLEKFEKTFITQGAYEDRTVFESLDQAWSLL 465 I ++ + + VG ++LS D+L+LE + + ++ Q A++D F S ++ +++L Sbjct: 470 ILQEEEQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDDVDTFTSREKQFNML 529 Query: 466 RI 467 ++ Sbjct: 530 KV 531 Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 33/99 (33%), Positives = 56/99 (56%), Gaps = 4/99 (4%) Query: 34 VNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGIDVKKTTV 93 V+GPLV+ E + I ++ L G+++E+R D A +QV+E TSGI + V Sbjct: 16 VSGPLVMAENMS---EASIQDMCLVGDLGVIGEIIEMRQDVASIQVYEETSGIGPGEP-V 71 Query: 94 EFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYL 132 TGE+L + + ++ ++FDG RP+D +V ++L Sbjct: 72 RSTGEALSVELGPGIISQMFDGIQRPLDTFMEVTQSNFL 110 >6FKI-F nrPDB Length = 498 Score = 104 bits (260), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 115/461 (24%), Positives = 200/461 (43%), Gaps = 55/461 (11%) Query: 11 INKKAVEQGFNVKPRLNYNTVSGVNGPLVILEKVKFP--RYNEIVNLTLPDGTVRQGQVL 68 IN + G + + N ++ + GP++ V FP + I N + G GQ + Sbjct: 3 INPTTSDPGVSTLEKKNLGRIAQIIGPVL---DVAFPPGKMPNIYNALIVKGRDTAGQPM 59 Query: 69 EIR--------GDRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPI 120 + +R T G+ ++ TG L +PV LGRIF+ G P+ Sbjct: 60 NVTCEVQQLLGNNRVRAVAMSATDGLTRGMEVID-TGAPLSVPVGGATLGRIFNVLGEPV 118 Query: 121 DN-GPKVFAEDYLDI-NGSPINPYARIYPE-----EMISTGVSAIDTMNSIARGQKIPIF 173 DN GP +D SPI+ A + + + TG+ +D + RG KI +F Sbjct: 119 DNLGP-------VDTRTTSPIHRSAPAFTQLDTKLSIFETGIKVVDLLAPYRRGGKIGLF 171 Query: 174 SASGLPH--------NEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFF 225 +G+ N IA + + +G++ ++ M E+ Sbjct: 172 GGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGND-----LYMEMK---ESGVIN 223 Query: 226 KQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYA 285 +Q+ E+ + +L N+P R+ ALT AEY E+ VL + ++ + Sbjct: 224 EQNIAES----KVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFV 279 Query: 286 DALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHP 345 A EVSA +P GY + T++ ++ ER + GSIT I + +P DD+T P Sbjct: 280 QAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERI--TSTKEGSITSIQAVYVPADDLTDP 337 Query: 346 IPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYA 405 P T + + R L KGIYP ++ L S S +++ I ++H +++ ++ Sbjct: 338 APATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRI----VGEEHYEIAQRVKE 393 Query: 406 KYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQ 446 K+ + A++G + LS ED+L++ K E+ F++Q Sbjct: 394 TLQRYKELQDIIAILGLDELSEEDRLTVARARKIER-FLSQ 433 >6F5D-A nrPDB Length = 560 Score = 102 bits (254), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 97/354 (27%), Positives = 160/354 (45%), Gaps = 20/354 (5%) Query: 49 YNEIVNLTLPDGTVRQGQVLEIRGD-RAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSED 107 YN I+ + + T G V + D R + + + + + + + TG+ L IPV Sbjct: 52 YNTIIQIQVSPTTFAAGLVFNLEKDGRIGIILMDNITEVQSGQKVMA-TGQLLHIPVGAG 110 Query: 108 MLGRIFDGSGRPIDNGPKVFAEDYLDIN------GSPINPYARIYPEEMISTGVSAIDTM 161 +LG++ + G + G + LD G+P N +R + TG A+DTM Sbjct: 111 VLGKVVNPLGHEVPVGLVTRSRRLLDSTLGKVDTGAP-NIVSRSPVNYNLLTGFKAVDTM 169 Query: 162 NSIARGQKIPIFSASGLPHNEIA-AQICRQAGLVRPTKDVHDGHEENFSI-VFAAMGVNL 219 I RGQ+ I IA + I Q VR + + +N I ++ ++G Sbjct: 170 IPIGRGQRELIVGDRQTGKTSIAVSTIINQ---VRINQQILS---KNAVISIYVSIGQRC 223 Query: 220 ETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILT 279 + + G+L T++ A +P + + P +T EY RH L + Sbjct: 224 SNVARIHRLLQSYGALRYTTVMAATAAEPAGLQYLAPYAGVTMGEYFM-NRGRHCLCVYD 282 Query: 280 DMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVE-GRNG-SITQIPILTM 337 D+S A A R++S PGR YPG ++ S + ERA + G+ G S+T +PI+ Sbjct: 283 DLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAMLSPGKGGGSVTALPIVET 342 Query: 338 PNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGM 391 ++D+T I IT+GQI++D +L G P +N+ S+SR+ SA M Sbjct: 343 LSNDVTAYIVTNVISITDGQIYLDTKLFTGGQRPAVNIGLSVSRVGSSAQNAAM 396 >5YBH-A nrPDB Length = 368 Score = 101 bits (252), Expect = 7e-22, Method: Compositional matrix adjust. Identities = 73/277 (26%), Positives = 131/277 (47%), Gaps = 40/277 (14%) Query: 118 RPIDNGPKVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASG 177 RP+DN P +++E R E+ TG+ ID++ + GQ++ IF+++G Sbjct: 55 RPVDNAPPLYSE--------------RAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAG 100 Query: 178 LPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVN----LETARFFKQDFEENG 233 + + +G D++ V +G ET + K +++ Sbjct: 101 CGKTFLMNMLIEHSG-----ADIY---------VIGLIGERGREVTETVDYLKNSEKKS- 145 Query: 234 SLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTD-MSSYADALREVS 292 R L ++ +++R +A AE+ ++TE H + + D ++ YA ALR+V+ Sbjct: 146 ---RCVLVYATSDYSSVDRCNAAYIATAIAEF--FRTEGHKVALFIDSLTRYARALRDVA 200 Query: 293 AAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGY 352 A E P RRGYP ++ L + ER G+++ GSIT + + +DD P+ + Sbjct: 201 LAAGESPARRGYPVSVFDSLPRLLERPGKLKA-GGSITAFYTVLLEDDDFADPLAEEVRS 259 Query: 353 ITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGE 389 I +G I++ R L KG +P I+ L S+SR+ + E Sbjct: 260 ILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDE 296 >6FOC-D nrPDB Length = 475 Score = 97.1 bits (240), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 104/425 (24%), Positives = 189/425 (44%), Gaps = 37/425 (8%) Query: 34 VNGPLVILEKVKFPRYN--EIVNLTLPD---GTVRQGQVLEIR---GDRAIVQV-FEGTS 84 + GP+V V+FPR + E+ N + G + + LE+ GD + + + T Sbjct: 15 ITGPVV---DVEFPRGSVPELFNALHAEITFGALAKTLTLEVAQHLGDSLVRCISMQPTD 71 Query: 85 GIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYAR 144 G+ V+ V TG S+ +PV + + G +F+ G +D+ ++ I+ P ++ Sbjct: 72 GL-VRGVEVTDTGASISVPVGDGVKGHVFNALGDCLDDPGYGKDFEHWSIHRKP-PAFSD 129 Query: 145 IYPE-EMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDG 203 + P EM+ TG+ +D + RG KI +F +G+ + ++ + Sbjct: 130 LEPRTEMLETGLKVVDLLTPYVRGGKIALFGGAGVGKTVLIQEMINRIA----------- 178 Query: 204 HEENF--SIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALT 261 NF + VFA +G + + L+ T+L ++P R+ ALT Sbjct: 179 --RNFGGTSVFAGVGERTREGNDLWVELADANVLKDTALVFGQMDEPPGTRMRVALSALT 236 Query: 262 TAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGR 321 AE+ + + VL + ++ + A EVS +P GY + ++ + ER Sbjct: 237 MAEFFRDEQGQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERITS 296 Query: 322 VEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSR 381 GR SIT + + +P DD T P P T + + R + +KGI+P ++ L S S Sbjct: 297 TRGR--SITSMQAVYVPADDYTDPAPATTFAHLDATTELSRAVFSKGIFPAVDPLASSST 354 Query: 382 LMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEK 441 ++ AI +H V+ ++ KD + A++G + LS EDK + + E+ Sbjct: 355 ILDPAI----VGDEHYRVAQEVIRILQRYKDLQDIIAILGIDELSEEDKQLVNRARRIER 410 Query: 442 TFITQ 446 F++Q Sbjct: 411 -FLSQ 414 >5BN5-A nrPDB Length = 570 Score = 94.0 bits (232), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 106/400 (26%), Positives = 170/400 (42%), Gaps = 39/400 (9%) Query: 92 TVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPY-------AR 144 TV G RI V ++ G+I + I G E +NG PI Y R Sbjct: 134 TVNENGFEHRIIVPPNVEGKIEE-----IYEGNFTIEETIAIVNGKPIKLYHEWPIRKPR 188 Query: 145 IYPEEM-----ISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAG--LVRPT 197 Y E++ TG +D M IA+G + G + QI + A +V Sbjct: 189 PYKEKLDYNYPFITGTRVLDIMFPIAKGGSAAVPGPFGSGKTVLNQQIAKWADSDIVIYI 248 Query: 198 KDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPR 257 G+E M LE K + RT L N +N P R + Sbjct: 249 GCGERGNE---------MTEVLEEFPKLKDPKTGKPLMYRTILIANTSNMPIAAREASIY 299 Query: 258 LALTTAEYLAYQTERHVLTILTDMSS-YADALREVSAAREEVPGRRGYPGYMYTDLSTIY 316 L T EY ++ + + + + D +S +A+ALRE+S+ E+P GYP Y+ L+ Y Sbjct: 300 LGATIGEY--FRDQGYSVVVNADSTSRWAEALREISSRLGEIPSEEGYPAYLLRKLAEFY 357 Query: 317 ERAGRVEGRN---GSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPI 373 ER+GRV N GS+T I ++ P D + P+ T + +D +L K YP I Sbjct: 358 ERSGRVRTLNDLEGSLTIIGAVSPPGGDFSEPVTQNTLRLVGALWALDSKLAYKRHYPAI 417 Query: 374 NVLPSLSR---LMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDK 430 N L S ++ +K E +D ++ + +A + + ++VG +ALS +K Sbjct: 418 NYLISYTKQWEFVKKYFEE--LYEDVIEIREEFFAILKRESELMDIVSIVGPDALSDNEK 475 Query: 431 LSLEFLEKFEKTFITQGAYEDRTVFESLDQAWSLLRIYPK 470 + L + F+ Q A+++ + L++ L+RI K Sbjct: 476 IYLHMGRIIREGFLQQDAFDENDSYSPLEKTIELMRIIHK 515 Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 36/95 (37%), Positives = 55/95 (57%), Gaps = 8/95 (8%) Query: 29 NTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQ-GQVLEIRGDRAIVQVFEGTSGID 87 N + +NGPLVI K KF + E+V + G + G+V+ I D+A +QV+E T+G+ Sbjct: 2 NRIISINGPLVI-AKGKFSIF-EVVRV----GEEKLIGEVIGIENDKAYIQVYEDTNGLK 55 Query: 88 VKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDN 122 V + TG+ L I + +L IFDG GRP+ + Sbjct: 56 VGEPVFN-TGKPLTIELGPGLLANIFDGLGRPLKD 89 >5Y60-A nrPDB Length = 578 Score = 86.7 bits (213), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 66/240 (27%), Positives = 118/240 (49%), Gaps = 10/240 (4%) Query: 235 LERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSS-YADALREVSA 293 + RT L N +N P R + + +T AEY ++ + + ++ D +S +A+ALRE+S+ Sbjct: 282 MHRTVLIANTSNMPVAAREASIYVGVTIAEY--FRDQGFSVALMADSTSRWAEALREISS 339 Query: 294 AREEVPGRRGYPGYMYTDLSTIYERAGRV---EGRNGSITQIPILTMPNDDITHPIPDLT 350 EE+P GYP Y+ L+ YERAG+V G G++T + ++ P D++ P+ T Sbjct: 340 RLEEMPAEEGYPPYLAARLAAFYERAGKVITLGGEEGAVTIVGAVSPPGGDMSEPVTQST 399 Query: 351 GYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIG 410 I +D L + +P IN S S L SA+ D A + Sbjct: 400 LRIVGAFWRLDASLAFRRHFPAINWNGSYS-LFTSALDPWYRENVAEDYPELRDAISELL 458 Query: 411 KDAAAMKAV---VGEEALSIEDKLSLEFLEKFEKTFITQGAYEDRTVFESLDQAWSLLRI 467 + A ++ + VG +AL ++L +E + F+ Q AY + + S+ +A+ ++++ Sbjct: 459 QREAGLQEIVQLVGPDALQDAERLVIEVGRIIREDFLQQNAYHEVDAYCSMKKAYGIMKM 518 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 31/94 (32%), Positives = 50/94 (53%), Gaps = 4/94 (4%) Query: 29 NTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGIDV 88 + + GP VI + + R +I + +G V G+++ + GD A VQV+E TSG+ V Sbjct: 4 GVIQKIAGPAVIAKGMLGARMYDICKVG-EEGLV--GEIIRLDGDTAFVQVYEDTSGLKV 60 Query: 89 KKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDN 122 + V TG L + + ML I+DG RP++ Sbjct: 61 GEPVVS-TGLPLAVELGPGMLNGIYDGIQRPLER 93 >6O7W-C nrPDB Length = 639 Score = 85.1 bits (209), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 67/254 (26%), Positives = 119/254 (46%), Gaps = 35/254 (13%) Query: 235 LERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAA 294 ++RT+L N +N P R + +T AEY Q ++V I S +A+ALRE+S Sbjct: 313 MKRTTLVANTSNMPVAAREASIYTGITLAEYFRDQG-KNVSMIADSSSRWAEALREISGR 371 Query: 295 REEVPGRRGYPGYMYTDLSTIYERAGRVEG-----RNGSITQIPILTMPNDDITHPIPDL 349 E+P +G+P Y+ L++ YERAG+ R GS++ + ++ D + P+ Sbjct: 372 LGEMPADQGFPAYLGAKLASFYERAGKAVALGSPDRTGSVSIVAAVSPAGGDFSDPVTTA 431 Query: 350 TGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLY-AKYA 408 T IT+ +D++L + +P IN S S+ + +V N+ Y + Y Sbjct: 432 TLGITQVFWGLDKKLAQRKHFPSINTSVSYSK--------------YTNVLNKFYDSNYP 477 Query: 409 -----------IGKDAAAMKAV---VGEEALSIEDKLSLEFLEKFEKTFITQGAYEDRTV 454 I +A ++ V VG+ ALS DK++L+ ++ F+ Q Y Sbjct: 478 EFPVLRDRMKEILSNAEELEQVVQLVGKSALSDSDKITLDVATLIKEDFLQQNGYSTYDA 537 Query: 455 FESLDQAWSLLRIY 468 F + + + ++R + Sbjct: 538 FCPIWKTFDMMRAF 551 Score = 48.5 bits (114), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 31/93 (33%), Positives = 52/93 (55%), Gaps = 4/93 (4%) Query: 28 YNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGID 87 Y + V+GP+VI E + E+V + D V G+V+ I GD+A +QV+E T+G+ Sbjct: 25 YGAIYSVSGPVVIAENMIGCAMYELVKVG-HDNLV--GEVIRIDGDKATIQVYEETAGLT 81 Query: 88 VKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPI 120 V + TG+ L + + ++ I+DG RP+ Sbjct: 82 VGDPVLR-TGKPLSVELGPGLMETIYDGIQRPL 113 >3MFY-A nrPDB Length = 588 Score = 82.4 bits (202), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 69/259 (26%), Positives = 126/259 (48%), Gaps = 18/259 (6%) Query: 235 LERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSS-YADALREVSA 293 +ERT L N +N P R + +T AEY ++ + + ++ D +S +A+ALRE+S Sbjct: 288 MERTVLIANTSNMPVAAREASIYTGITIAEY--FRDMGYDVALMADSTSRWAEALREISG 345 Query: 294 AREEVPGRRGYPGYMYTDLSTIYERAGRV-----EGRNGSITQIPILTMPNDDITHPIPD 348 EE+PG GYP Y+ + L+ YERAGRV + R GS++ I ++ P D + P+ Sbjct: 346 RLEEMPGEEGYPAYLASKLAEFYERAGRVVTLGSDYRVGSVSVIGAVSPPGGDFSEPVVQ 405 Query: 349 LTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRK---DHGDVSNQLYA 405 T + + +D L + +P IN L S S L A+ + + + + ++ A Sbjct: 406 NTLRVVKVFWALDADLARRRHFPAINWLTSYS-LYVDAVKDWWHKNIDPEWKAMRDKAMA 464 Query: 406 KYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQGAYEDRTVFESLDQAWSLL 465 + + +VG +AL ++ L + ++ Q A+++ + ++ +++ Sbjct: 465 LLQKESELQEIVRIVGPDALPERERAILLVARMLREDYLQQDAFDEVDTYCPPEKQVTMM 524 Query: 466 RI----YPKEM--LNRISP 478 R+ Y K M +NR P Sbjct: 525 RVLLNFYDKTMEAINRGVP 543 Score = 48.5 bits (114), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 29/88 (32%), Positives = 53/88 (60%), Gaps = 4/88 (4%) Query: 34 VNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGIDVKKTTV 93 V GPLV+ + +K + E+V + G + G+++ + GD+A++QV+E T+G+ + V Sbjct: 10 VTGPLVVADGMKGAKMYEVVRVG-ELGLI--GEIIRLEGDKAVIQVYEETAGVRPGEPVV 66 Query: 94 EFTGESLRIPVSEDMLGRIFDGSGRPID 121 TG SL + + +L I+DG RP++ Sbjct: 67 G-TGASLSVELGPRLLTSIYDGIQRPLE 93 >5N9J-W nrPDB Length = 545 Score = 32.7 bits (73), Expect = 0.40, Method: Compositional matrix adjust. Identities = 46/186 (24%), Positives = 82/186 (44%), Gaps = 35/186 (18%) Query: 93 VEFTGESLRIPVSEDMLGRI-FDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPEEMI 151 V FTG+ + +P+S+D + RI + S + ++G F ED + N + I E+ + Sbjct: 326 VNFTGDEILVPISDDHVVRITLETSSKNTESG---FTEDKKSNEDTSTN-FVTIKQEKEL 381 Query: 152 STGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIV 211 + DT+N+IA +F L H CR++ +++ + N ++ Sbjct: 382 LKCL--CDTLNAIAH----ILF----LKH-------CRKSDRRSQQPELYMAIDANAPLI 424 Query: 212 FAAM----GVN---LETARFFKQ-----DFEENGSLERTSLFLNLANDPTIERI-ITPRL 258 + +N LE R+ KQ F N E+ FL L N +I R+ I+ R+ Sbjct: 425 LRPLIFYYNLNQESLEFQRWLKQRDISFKFMPNYPWEKAKDFLELENSLSINRLSISWRI 484 Query: 259 ALTTAE 264 ++ E Sbjct: 485 MVSNFE 490 >4OI0-A nrPDB Length = 431 Score = 32.7 bits (73), Expect = 0.44, Method: Compositional matrix adjust. Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 1/66 (1%) Query: 147 PEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEE 206 P ++ T VS I S+ +G + PIF + N ++ A LV+ T DV DG E Sbjct: 125 PTDVGKTTVSRILCNYSVRQG-RTPIFVELDVGQNSVSVPGTVAAVLVQKTADVIDGFER 183 Query: 207 NFSIVF 212 N IVF Sbjct: 184 NQPIVF 189 >1HPL-A nrPDB Length = 449 Score = 32.3 bits (72), Expect = 0.50, Method: Compositional matrix adjust. Identities = 13/18 (72%), Positives = 15/18 (83%) Query: 41 LEKVKFPRYNEIVNLTLP 58 LEKVKF YN ++NLTLP Sbjct: 396 LEKVKFIWYNNVINLTLP 413 >4H63-Q nrPDB Length = 469 Score = 32.3 bits (72), Expect = 0.51, Method: Compositional matrix adjust. Identities = 46/186 (24%), Positives = 82/186 (44%), Gaps = 35/186 (18%) Query: 93 VEFTGESLRIPVSEDMLGRI-FDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPEEMI 151 V FTG+ + +P+S+D + RI + S + ++G F ED + N + I E+ + Sbjct: 250 VNFTGDEILVPISDDHVVRITLETSSKNTESG---FTEDKKSNEDTSTN-FVTIKQEKEL 305 Query: 152 STGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIV 211 + DT+N+IA +F L H CR++ +++ + N ++ Sbjct: 306 LKCL--CDTLNAIAH----ILF----LKH-------CRKSDRRSQQPELYMAIDANAPLI 348 Query: 212 FAAM----GVN---LETARFFKQ-----DFEENGSLERTSLFLNLANDPTIERI-ITPRL 258 + +N LE R+ KQ F N E+ FL L N +I R+ I+ R+ Sbjct: 349 LRPLIFYYNLNQESLEFQRWLKQRDISFKFMPNYPWEKAKDFLELENSLSINRLSISWRI 408 Query: 259 ALTTAE 264 ++ E Sbjct: 409 MVSNFE 414 >5EQT-A nrPDB Length = 257 Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust. Identities = 24/85 (28%), Positives = 43/85 (50%), Gaps = 11/85 (12%) Query: 19 GFNVKPRLNYNTVSGVNGPLVILEKVKFP-RYNEIVNLTLPDGTVR------QGQVLEIR 71 GF+ PR N ++ N P ++ + P R++ ++ + LPD R + ++++ Sbjct: 138 GFD--PRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKLK 195 Query: 72 GD--RAIVQVFEGTSGIDVKKTTVE 94 G RAI ++ EG SG D+K E Sbjct: 196 GVDLRAIAEMTEGASGADLKAIATE 220 >3L9S-A nrPDB Length = 191 Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust. Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 9/62 (14%) Query: 409 IGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQGAYEDRTVF-------ESLDQA 461 +GK+ AV AL +EDK+++ E +KT Q A + R VF E D A Sbjct: 70 LGKELTQAWAVA--MALGVEDKVTVPLFEAVQKTQTVQSAADIRKVFVDAGVKGEDYDAA 127 Query: 462 WS 463 W+ Sbjct: 128 WN 129 >4N7B-A nrPDB Length = 541 Score = 30.0 bits (66), Expect = 2.4, Method: Compositional matrix adjust. Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 7/69 (10%) Query: 152 STGVS-AIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAG--LVRPTKDVHDGHEENF 208 GVS AI+T+ + K PI+ + HN+I + + G + DV DGH Sbjct: 231 CKGVSRAIETVEECLKLFKPPIYVKHKIVHNDIVCKKLEKEGAIFIEDLNDVPDGH---- 286 Query: 209 SIVFAAMGV 217 ++++A G+ Sbjct: 287 ILIYSAHGI 295 >1YJS-A nrPDB Length = 419 Score = 30.0 bits (66), Expect = 2.5, Method: Compositional matrix adjust. Identities = 36/133 (27%), Positives = 51/133 (38%), Gaps = 18/133 (13%) Query: 132 LDINGSPI-NPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGL---PHNEIAAQI 187 ++ GS + N YA YP G +D + +AR + +F A PH+ A + Sbjct: 40 MEAQGSVLTNKYAEGYPGRRYYGGCEYVDIVEELARERAKQLFGAEHANVQPHSGAQANM 99 Query: 188 CRQAGLVRPTKDV------HDGHEE-----NFSIV---FAAMGVNLETARFFKQDFEENG 233 ++ V H GH NFS V F A GV+ ET D E Sbjct: 100 AVYFTVLEHGDTVLGMNLSHGGHLTHGSPVNFSGVQYNFVAYGVDPETHVIDYDDVREKA 159 Query: 234 SLERTSLFLNLAN 246 L R L + A+ Sbjct: 160 RLHRPKLIVAAAS 172 >4TKY-A nrPDB Length = 191 Score = 29.6 bits (65), Expect = 3.5, Method: Compositional matrix adjust. Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 9/62 (14%) Query: 409 IGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQGAYEDRTVF-------ESLDQA 461 +GKD AV AL +EDK+++ E +KT + A + R VF E D A Sbjct: 70 LGKDLTQAWAVA--MALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAA 127 Query: 462 WS 463 W+ Sbjct: 128 WN 129 >4MCU-A nrPDB Length = 190 Score = 29.3 bits (64), Expect = 3.8, Method: Compositional matrix adjust. Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 9/62 (14%) Query: 409 IGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQGAYEDRTVF-------ESLDQA 461 +GKD AV AL +EDK++ E +KT Q + R VF E D A Sbjct: 69 LGKDLTQAWAVA--IALGVEDKITAPMFEAVQKTQTVQSVADIRKVFVDAGVKGEDYDAA 126 Query: 462 WS 463 W+ Sbjct: 127 WN 128 >1X7P-A nrPDB Length = 287 Score = 29.3 bits (64), Expect = 3.9, Method: Compositional matrix adjust. Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 1/45 (2%) Query: 93 VEFTGESL-RIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDING 136 VE + L RIPV ED LG +FD P + G + + D L +G Sbjct: 110 VEMPADDLDRIPVREDFLGVLFDRPTSPGNIGSIIRSADALGAHG 154 >1RYX-A nrPDB Length = 686 Score = 28.9 bits (63), Expect = 5.6, Method: Compositional matrix adjust. Identities = 13/35 (37%), Positives = 18/35 (51%) Query: 174 SASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENF 208 A G P N Q+C+ +G + P K V HE+ F Sbjct: 488 CAPGSPPNSRLCQLCQGSGGIPPEKCVASSHEKYF 522 >2B4Q-A nrPDB Length = 276 Score = 28.9 bits (63), Expect = 5.9, Method: Compositional matrix adjust. Identities = 24/79 (30%), Positives = 32/79 (40%), Gaps = 7/79 (8%) Query: 94 EFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPEEMIST 153 E GE + + V GR R I N P+ D I P+ + R PEEM + Sbjct: 199 ELVGEHINVNVIAP--GRFPSRMTRHIANDPQALEADSASI---PMGRWGR--PEEMAAL 251 Query: 154 GVSAIDTMNSIARGQKIPI 172 +S T + G IPI Sbjct: 252 AISLAGTAGAYMTGNVIPI 270 >4WUZ-A nrPDB Length = 229 Score = 28.5 bits (62), Expect = 6.5, Method: Compositional matrix adjust. Identities = 15/39 (38%), Positives = 24/39 (61%), Gaps = 2/39 (5%) Query: 79 VFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSG 117 +FE TSG++V ++ + + ES+R S D G DG+G Sbjct: 94 LFEFTSGVNVTESPIIYRDESMRTACSPD--GLCSDGNG 130 >1BYO-A nrPDB Length = 99 Score = 28.5 bits (62), Expect = 7.6, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 34/68 (50%), Gaps = 5/68 (7%) Query: 154 GVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAG-----LVRPTKDVHDGHEENF 208 G++ + + SIA G+KI + +G PHN++ + AG + P +D+ + E + Sbjct: 11 GLAFVPSDLSIASGEKITFKNNAGFPHNDLFDEDEVPAGVDVTKISMPEEDLLNAPGEEY 70 Query: 209 SIVFAAMG 216 S+ G Sbjct: 71 SVTLTEKG 78 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3J9V-F nrPDB 688 0.0 3B2Q-A nrPDB 526 e-149 5Y5Y-D nrPDB 521 e-148 3VR3-D nrPDB 516 e-147 5IK2-D nrPDB 464 e-131 2XOK-D nrPDB 443 e-125 6FKI-F nrPDB 440 e-124 5LQY-D nrPDB 438 e-123 5FL7-D nrPDB 438 e-123 4XD7-D nrPDB 436 e-122 4Q4L-A nrPDB 431 e-121 2XND-D nrPDB 429 e-120 2W6I-D nrPDB 428 e-120 6FOC-D nrPDB 423 e-118 5CDF-E nrPDB 422 e-118 2W6E-A nrPDB 420 e-118 2XND-A nrPDB 418 e-117 5T4O-D nrPDB 412 e-115 5HKK-A nrPDB 405 e-113 6F5D-D nrPDB 401 e-112 5LQZ-A nrPDB 397 e-111 3OFN-A nrPDB 396 e-110 6N2Y-A nrPDB 392 e-109 5FL7-A nrPDB 392 e-109 5DN6-A nrPDB 391 e-109 2R9V-A nrPDB 389 e-108 5BO5-A nrPDB 384 e-107 6FKI-E nrPDB 379 e-105 5T4O-A nrPDB 375 e-104 6FOC-A nrPDB 373 e-103 6F5D-A nrPDB 363 e-101 6NJP-A nrPDB 359 2e-99 2DPY-A nrPDB 345 2e-95 5BN5-A nrPDB 343 1e-94 2OBL-A nrPDB 325 3e-89 3MFY-A nrPDB 314 8e-86 5Y60-A nrPDB 306 2e-83 4NPH-A nrPDB 304 5e-83 6O7W-C nrPDB 297 1e-80 3VR3-A nrPDB 295 4e-80 5YBH-A nrPDB 295 4e-80 Sequences not found previously or not previously below threshold: 3L0O-A nrPDB 100 2e-21 3ICE-A nrPDB 92 5e-19 3BUJ-A nrPDB 35 0.10 6HA8-V nrPDB 34 0.11 5ZXD-A nrPDB 33 0.26 5VFU-A nrPDB 33 0.26 5YJJ-A nrPDB 33 0.27 5LXZ-B nrPDB 33 0.28 6DUE-A nrPDB 33 0.29 6OME-A nrPDB 33 0.35 3HR8-A nrPDB 33 0.35 5XEX-A nrPDB 33 0.37 1XZP-A nrPDB 33 0.41 6EPC-H nrPDB 32 0.46 3D8B-A nrPDB 32 0.50 4D81-A nrPDB 32 0.56 4LGM-A nrPDB 32 0.59 2FEZ-A nrPDB 32 0.63 6QUZ-B nrPDB 32 0.87 1JI0-A nrPDB 32 0.87 4Q7L-A nrPDB 31 1.0 6IC4-I nrPDB 31 1.2 5VHO-A nrPDB 31 1.4 4H51-A nrPDB 31 1.6 4RY2-A nrPDB 31 1.7 3PXI-A nrPDB 30 2.2 4Z8X-A nrPDB 30 2.7 3PXG-A nrPDB 30 2.7 4FIN-A nrPDB 30 3.0 5X41-A nrPDB 30 3.1 3A22-A nrPDB 30 3.2 5FM7-A nrPDB 29 3.8 1XP8-A nrPDB 29 4.9 3NHB-A nrPDB 29 6.1 6BLB-A nrPDB 28 8.2 4MRS-A nrPDB 28 9.6 >3J9V-F nrPDB Length = 517 Score = 688 bits (1776), Expect = 0.0, Method: Composition-based stats. Identities = 517/517 (100%), Positives = 517/517 (100%) Query: 1 MVLSDKELFAINKKAVEQGFNVKPRLNYNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDG 60 MVLSDKELFAINKKAVEQGFNVKPRLNYNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDG Sbjct: 1 MVLSDKELFAINKKAVEQGFNVKPRLNYNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDG 60 Query: 61 TVRQGQVLEIRGDRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPI 120 TVRQGQVLEIRGDRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPI Sbjct: 61 TVRQGQVLEIRGDRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPI 120 Query: 121 DNGPKVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPH 180 DNGPKVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPH Sbjct: 121 DNGPKVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPH 180 Query: 181 NEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSL 240 NEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSL Sbjct: 181 NEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSL 240 Query: 241 FLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPG 300 FLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPG Sbjct: 241 FLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPG 300 Query: 301 RRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFV 360 RRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFV Sbjct: 301 RRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFV 360 Query: 361 DRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVV 420 DRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVV Sbjct: 361 DRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVV 420 Query: 421 GEEALSIEDKLSLEFLEKFEKTFITQGAYEDRTVFESLDQAWSLLRIYPKEMLNRISPKI 480 GEEALSIEDKLSLEFLEKFEKTFITQGAYEDRTVFESLDQAWSLLRIYPKEMLNRISPKI Sbjct: 421 GEEALSIEDKLSLEFLEKFEKTFITQGAYEDRTVFESLDQAWSLLRIYPKEMLNRISPKI 480 Query: 481 LDEFYDRARDDADEDEEDPDTRSSGKKKDASQEESLI 517 LDEFYDRARDDADEDEEDPDTRSSGKKKDASQEESLI Sbjct: 481 LDEFYDRARDDADEDEEDPDTRSSGKKKDASQEESLI 517 >3B2Q-A nrPDB Length = 469 Score = 526 bits (1354), Expect = e-149, Method: Composition-based stats. Identities = 268/464 (57%), Positives = 343/464 (73%), Gaps = 9/464 (1%) Query: 26 LNYNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSG 85 Y T++ + GPL+ +EK + YNEIVN+ + DGTVR+GQVL+ D +VQVFEGT G Sbjct: 12 KEYKTITQIAGPLIFVEKTEPVGYNEIVNIKMGDGTVRRGQVLDSSADIVVVQVFEGTGG 71 Query: 86 IDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARI 145 +D K V FTGE+L++P S D+LGRI GSG P D GP++ + LDING+ +NPYAR+ Sbjct: 72 LD-KDCGVIFTGETLKLPASVDLLGRILSGSGEPRDGGPRIVPDQLLDINGAAMNPYARL 130 Query: 146 YPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHE 205 P++ I TG+S ID N++ RGQK+PIFSASGLPHNEIA QI RQA + G E Sbjct: 131 PPKDFIQTGISTIDGTNTLVRGQKLPIFSASGLPHNEIALQIARQASV--------PGSE 182 Query: 206 ENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEY 265 F++VFAAMG+ E A++F DFE+ G+LER +FLNLA+DP +ERI+TPR+ALT AEY Sbjct: 183 SAFAVVFAAMGITNEEAQYFMSDFEKTGALERAVVFLNLADDPAVERIVTPRMALTAAEY 242 Query: 266 LAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGR 325 LAY+ HVL ILTD+++YA+ALR++ AAR EVPGRRGYPGYMYTDL+T+YERAG V+G Sbjct: 243 LAYEHGMHVLVILTDITNYAEALRQMGAARNEVPGRRGYPGYMYTDLATLYERAGIVKGA 302 Query: 326 NGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKS 385 GS+TQIPIL+MP DDITHPIPDL+GYITEGQI V R+LH KGIYPPINVLPSLSRLM S Sbjct: 303 KGSVTQIPILSMPGDDITHPIPDLSGYITEGQIVVARELHRKGIYPPINVLPSLSRLMNS 362 Query: 386 AIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFIT 445 IG G TR+DH VS+Q+YA YA G+D + A+VG+EALS D LEF + FE F+ Sbjct: 363 GIGAGKTREDHKAVSDQMYAGYAEGRDLRGLVAIVGKEALSERDTKFLEFADLFEDKFVR 422 Query: 446 QGAYEDRTVFESLDQAWSLLRIYPKEMLNRISPKILDEFYDRAR 489 QG E+RT+ ++L+ W +L P+ L RI K + +++ R Sbjct: 423 QGWNENRTIEDTLEIGWQILTHLPENQLGRIDNKYIQKYHPAHR 466 >5Y5Y-D nrPDB Length = 478 Score = 521 bits (1341), Expect = e-148, Method: Composition-based stats. Identities = 254/461 (55%), Positives = 336/461 (72%), Gaps = 2/461 (0%) Query: 25 RLNYNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTS 84 + Y ++ ++GPL+ +E K Y IV++ G VR GQV+E+ + A++QVFE T+ Sbjct: 5 KKEYTGITYISGPLLFVENAKDLAYGAIVDIKDGTGRVRGGQVIEVSEEYAVIQVFEETT 64 Query: 85 GIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYAR 144 G+D+ T+V + R+ VS++MLGR F+G G+PID P + E L I G P+NP AR Sbjct: 65 GLDLATTSVSLVEDVARLGVSKEMLGRRFNGIGKPIDGLPPITPEKRLPITGLPLNPVAR 124 Query: 145 IYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGH 204 PE+ I TG+S ID MN++ RGQK+PIFS SGLP NEIAAQI RQA VRP Sbjct: 125 RKPEQFIQTGISTIDVMNTLVRGQKLPIFSGSGLPANEIAAQIARQAT-VRPDLSGEGEK 183 Query: 205 EENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAE 264 EE F++VFAAMG+ +F Q+FE G+L R+ LFLN A+DPTIERI+TPR+ALT AE Sbjct: 184 EEPFAVVFAAMGITQRELSYFIQEFERTGALSRSVLFLNKADDPTIERILTPRMALTVAE 243 Query: 265 YLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEG 324 YLA++ + HVL ILTDM++Y +ALRE+ AAREE+PGRRGYPGYMYTDL+TIYERAG VEG Sbjct: 244 YLAFEHDYHVLVILTDMTNYCEALREIGAAREEIPGRRGYPGYMYTDLATIYERAGVVEG 303 Query: 325 RNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMK 384 + GS+TQIPIL+MP+DD THPIPDLTGYITEGQI + R+LH KGIYPPI+ LPSLSRLM Sbjct: 304 KKGSVTQIPILSMPDDDRTHPIPDLTGYITEGQIQLSRELHRKGIYPPIDPLPSLSRLMN 363 Query: 385 SAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFI 444 + +G+G TR+DH VS+QLY+ YA G D + A++GE+AL+ D+ L+F + FE+ FI Sbjct: 364 NGVGKGKTREDHKQVSDQLYSAYANGVDIRKLVAIIGEDALTENDRRYLQFADAFERFFI 423 Query: 445 TQGAYEDRTVFESLDQAWSLLRIYPKEMLNRISPKILDEFY 485 QG ++R++ ESL AW+LL + P+ L RIS + ++Y Sbjct: 424 NQGQ-QNRSIEESLQIAWALLSMLPQGELKRISKDHIGKYY 463 >3VR3-D nrPDB Length = 465 Score = 516 bits (1329), Expect = e-147, Method: Composition-based stats. Identities = 258/464 (55%), Positives = 343/464 (73%), Gaps = 8/464 (1%) Query: 26 LNYNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSG 85 Y T+ V GPL+ +EKV +Y E++ + + +G +R+GQVLE++ D+A+VQ+FEGTSG Sbjct: 10 KEYRTIKEVVGPLMAVEKVSGVKYEELIEVRMQNGEIRRGQVLEVQEDKAMVQIFEGTSG 69 Query: 86 IDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARI 145 I++K ++V F G L++ VSEDM+GR+FDG GRP DNGP++ E YLDING INP AR Sbjct: 70 INLKNSSVRFLGHPLQLGVSEDMIGRVFDGLGRPKDNGPEILPEKYLDINGEVINPIARD 129 Query: 146 YPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHE 205 YP+E I TG+SAID +N++ RGQK+P+FS SGLPH E+AAQI RQA ++ + D Sbjct: 130 YPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKELAAQIARQATVLDSSDD------ 183 Query: 206 ENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEY 265 F++VFAA+G+ E A FF +DF + G+++R+ +F+NLANDP IERI TPR+ALT AEY Sbjct: 184 --FAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPAIERIATPRMALTAAEY 241 Query: 266 LAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGR 325 LAY+ HVL I+TDM++YA+ALRE+SAAR EVPGRRGYPGY+YT+L+T++ERAGR+ G Sbjct: 242 LAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGYLYTNLATLFERAGRIRGL 301 Query: 326 NGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKS 385 GS+TQIPILTMP DD THPIPDLTGYITEGQI + R+L+ GI PPI+VLPSLSRL Sbjct: 302 KGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELYKSGIQPPIDVLPSLSRLKDK 361 Query: 386 AIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFIT 445 G G TR+DH NQL+A YA GK A + V+GE ALS DK+ +F E+FE ++ Sbjct: 362 GTGAGKTREDHAATMNQLFAAYAQGKQAKELAVVLGESALSDIDKIYAKFAERFENEYVN 421 Query: 446 QGAYEDRTVFESLDQAWSLLRIYPKEMLNRISPKILDEFYDRAR 489 QG Y +RT+ E+LD W LL + P+ L RI +LD++ + Sbjct: 422 QGFYTNRTITETLDLGWELLAMLPRTELKRIKDDLLDKYLPEGK 465 >5IK2-D nrPDB Length = 462 Score = 464 bits (1194), Expect = e-131, Method: Composition-based stats. Identities = 113/471 (23%), Positives = 204/471 (43%), Gaps = 30/471 (6%) Query: 26 LNYNTVSGVNGPLVIL--EKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGT 83 +N + V GP+V + E + P + + P G + GD + V + Sbjct: 1 MNKGRIIQVMGPVVDIQFESGQLPDIYNAITIERPQGGTLTVEAAVHLGDNVVRCVAMAS 60 Query: 84 SGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYA 143 + V+ TG + +PV + LGR+F+ G PID +V AE+ I+ Sbjct: 61 TDGLVRGLEAVDTGAPISVPVGKATLGRVFNVLGEPIDEQGEVNAEERHPIHRPAPEFEE 120 Query: 144 RIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDG 203 +E++ TG+ ID + A+G KI +F +G+ + ++ H G Sbjct: 121 LSTADEILETGIKVIDLLAPYAKGGKIGLFGGAGVGKTVLIQELIN------NVAQEHGG 174 Query: 204 HEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTA 263 VFA +G + +++G + +TS+ N+P R+ LT A Sbjct: 175 LS-----VFAGVGERTREGNDLYHEMKDSGVISKTSMVFGQMNEPPGARLRVALTGLTMA 229 Query: 264 EYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVE 323 EY + + VL + ++ + A EVSA +P GY + T++ + ER Sbjct: 230 EYFRDREGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERI--TS 287 Query: 324 GRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLM 383 + GSIT I + +P DD T P P T + ++R+L GIYP ++ L S SR++ Sbjct: 288 TKKGSITSIQAIYVPADDYTDPAPATTFAHLDATTNLERKLAEMGIYPAVDPLASTSRIL 347 Query: 384 KSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTF 443 A+ ++H V+ + D + A++G + LS EDKL + K ++ F Sbjct: 348 SPAV----VGEEHYRVARGVQQVLQRYNDLQDIIAILGMDELSDEDKLIVARARKIQR-F 402 Query: 444 ITQGAYEDRTVFESLDQAWSLL--RIYPKEMLNRISPKILDEFYDRARDDA 492 ++Q + + + ++ + + P + R +IL+ +D ++A Sbjct: 403 LSQPFH--------VAEQFTGMPGKYVPVKETVRGFKEILEGKHDNLPEEA 445 >2XOK-D nrPDB Length = 511 Score = 443 bits (1140), Expect = e-125, Method: Composition-based stats. Identities = 106/426 (24%), Positives = 191/426 (44%), Gaps = 28/426 (6%) Query: 29 NTVSGVNGPLVIL--EKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQV-FEGTSG 85 V+ V G +V + E+ + P + + P G + +V + G+ + + +GT G Sbjct: 44 GKVTAVIGAIVDVHFEQSELPAILNALEIKTPQGKLVL-EVAQHLGENTVRTIAMDGTEG 102 Query: 86 IDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARI 145 + V+ V TG + +PV + LGRI + G PID + ++ I+ P + + Sbjct: 103 L-VRGEKVLDTGGPISVPVGRETLGRIINVIGEPIDERGPIKSKLRKPIHADPPSFAEQS 161 Query: 146 YPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHE 205 E++ TG+ +D + ARG KI +F +G+ ++ H G Sbjct: 162 TSAEILETGIKVVDLLAPYARGGKIGLFGGAGVGKTVFIQELIN------NIAKAHGGFS 215 Query: 206 ENFSIVFAAMGVNLETARFFKQDFEENGSL-----ERTSLFLNLANDPTIERIITPRLAL 260 VF +G ++ +E G + + +L N+P R L Sbjct: 216 -----VFTGVGERTREGNDLYREMKETGVINLEGESKVALVFGQMNEPPGARARVALTGL 270 Query: 261 TTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAG 320 T AEY + + VL + ++ + A EVSA +P GY + TD+ + ER Sbjct: 271 TIAEYFRDEEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGLLQERI- 329 Query: 321 RVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLS 380 + GS+T + + +P DD+T P P T + + R + GIYP ++ L S S Sbjct: 330 -TTTKKGSVTSVQAVYVPADDLTDPAPATTFAHLDATTVLSRGISELGIYPAVDPLDSKS 388 Query: 381 RLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFE 440 RL+ +A+ ++H DV++++ K + A++G + LS +DKL++E K + Sbjct: 389 RLLDAAV----VGQEHYDVASKVQETLQTYKSLQDIIAILGMDELSEQDKLTVERARKIQ 444 Query: 441 KTFITQ 446 + F++Q Sbjct: 445 R-FLSQ 449 >6FKI-F nrPDB Length = 498 Score = 440 bits (1131), Expect = e-124, Method: Composition-based stats. Identities = 108/456 (23%), Positives = 187/456 (41%), Gaps = 39/456 (8%) Query: 11 INKKAVEQGFNVKPRLNYNTVSGVNGPLVILEKVKFP--RYNEIVNLTLPDGTVRQGQVL 68 IN + G + + N ++ + GP++ V FP + I N + G GQ + Sbjct: 3 INPTTSDPGVSTLEKKNLGRIAQIIGPVL---DVAFPPGKMPNIYNALIVKGRDTAGQPM 59 Query: 69 EIR--------GDRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPI 120 + +R T G+ + V TG L +PV LGRIF+ G P+ Sbjct: 60 NVTCEVQQLLGNNRVRAVAMSATDGLT-RGMEVIDTGAPLSVPVGGATLGRIFNVLGEPV 118 Query: 121 DNGPKVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPH 180 DN V I+ S + TG+ +D + RG KI +F +G+ Sbjct: 119 DNLGPVDTRTTSPIHRSAPAFTQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGK 178 Query: 181 NEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSL----- 235 + ++ H G + + +E+G + Sbjct: 179 TVLIMELIN------NIAKAHGGVSVFGGVG-----ERTREGNDLYMEMKESGVINEQNI 227 Query: 236 --ERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSA 293 + +L N+P R+ ALT AEY E+ VL + ++ + A EVSA Sbjct: 228 AESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSA 287 Query: 294 AREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYI 353 +P GY + T++ ++ ER + GSIT I + +P DD+T P P T Sbjct: 288 LLGRMPSAVGYQPTLSTEMGSLQERI--TSTKEGSITSIQAVYVPADDLTDPAPATTFAH 345 Query: 354 TEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDA 413 + + R L KGIYP ++ L S S +++ I ++H +++ ++ K+ Sbjct: 346 LDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRI----VGEEHYEIAQRVKETLQRYKEL 401 Query: 414 AAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQGAY 449 + A++G + LS ED+L++ K E+ F++Q + Sbjct: 402 QDIIAILGLDELSEEDRLTVARARKIER-FLSQPFF 436 >5LQY-D nrPDB Length = 476 Score = 438 bits (1125), Expect = e-123, Method: Composition-based stats. Identities = 105/426 (24%), Positives = 185/426 (43%), Gaps = 27/426 (6%) Query: 29 NTVSGVNGPLVIL--EKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQV-FEGTSG 85 + V G +V + E+ + P + + + +V + G+ A+ + +GT G Sbjct: 8 GKIRAVIGAVVDVQFEQGELPAILNALTIDQGNNQKLVLEVAQHLGENAVRAIAMDGTEG 67 Query: 86 IDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARI 145 + V+ TV TG + +PV LGRI + G PID + + I+ P + + Sbjct: 68 L-VRGQTVVDTGAPISVPVGRGTLGRIINVVGEPIDERGPIECKQRNPIHADPPSFVEQS 126 Query: 146 YPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHE 205 E++ TG+ +D + ARG KI +F +G+ ++ H G Sbjct: 127 TEAEVLETGIKVVDLLAPYARGGKIGLFGGAGVGKTVFIQELIN------NIAKAHGGFS 180 Query: 206 ENFSIVFAAMGVNLETARFFKQDFEENGSL-----ERTSLFLNLANDPTIERIITPRLAL 260 VF +G ++ +E G + + +L N+P R L Sbjct: 181 -----VFTGVGERTREGNDLYREMKETGVINLEGESKVALVFGQMNEPPGARARVALTGL 235 Query: 261 TTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAG 320 T AEY + + VL + ++ + A EVSA +P GY + TD+ + ER Sbjct: 236 TIAEYFRDEEGQDVLLFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGLLQERI- 294 Query: 321 RVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLS 380 R GS+T + + +P DD+T P P T + + R + GIYP ++ L S S Sbjct: 295 -TTTRKGSVTSVQAVYVPADDLTDPAPATTFAHLDATTVLSRGISELGIYPAVDPLDSKS 353 Query: 381 RLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFE 440 RL+ ++ ++H DV+ + K + A++G + LS +DKL++E K + Sbjct: 354 RLLDVSV----VGQEHYDVATGVQQTLQAYKSLQDIIAILGMDELSEQDKLTVERARKIQ 409 Query: 441 KTFITQ 446 + F++Q Sbjct: 410 R-FLSQ 414 >5FL7-D nrPDB Length = 509 Score = 438 bits (1125), Expect = e-123, Method: Composition-based stats. Identities = 108/436 (24%), Positives = 188/436 (43%), Gaps = 27/436 (6%) Query: 19 GFNVKPRLNYNTVSGVNGPLVIL--EKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAI 76 G + + V G +V + E+ P + + +G +V + G+ + Sbjct: 31 GMASSAGVGSGKIRTVIGAVVDVQFEQDNLPAILNALTIDRGEGNKLVLEVAQHLGENTV 90 Query: 77 VQV-FEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDIN 135 + +GT G+ V+ T+V TG + IPV LGRI + G PID + A +L I+ Sbjct: 91 RTIAMDGTEGL-VRGTSVADTGAPITIPVGRGTLGRIINVCGEPIDERGPIEATKFLPIH 149 Query: 136 GSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVR 195 P + E++ TG+ +D + ARG KI +F +G+ ++ Sbjct: 150 ADPPTFAEQSTTAEVLETGIKVVDLLAPYARGGKIGLFGGAGVGKTVFIQELIN------ 203 Query: 196 PTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSL-----ERTSLFLNLANDPTI 250 H G VF +G ++ +E G + + +L N+P Sbjct: 204 NIAKAHGGFS-----VFCGVGERTREGNDLYREMKETGVINLEGESKVTLVFGQMNEPPG 258 Query: 251 ERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYT 310 R LT AEY + + VL + ++ + A EVSA +P GY + T Sbjct: 259 ARARVALTGLTIAEYFRDEEGQDVLLFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLAT 318 Query: 311 DLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIY 370 D+ + ER + GS+T + + +P DD+T P P T + + R + GIY Sbjct: 319 DMGALQERI--TTTQKGSVTSVQAVYVPADDLTDPAPATTFAHLDATTVLSRGISELGIY 376 Query: 371 PPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDK 430 P ++ L S SRL+ + ++H DV++ + K + A++G + LS +DK Sbjct: 377 PAVDPLDSKSRLLDIDV----VGQEHYDVASNVQQTLQAYKSLQDIIAILGMDELSEQDK 432 Query: 431 LSLEFLEKFEKTFITQ 446 L++E K ++ F++Q Sbjct: 433 LTVERARKIQR-FLSQ 447 >4XD7-D nrPDB Length = 483 Score = 436 bits (1120), Expect = e-122, Method: Composition-based stats. Identities = 100/430 (23%), Positives = 178/430 (41%), Gaps = 27/430 (6%) Query: 29 NTVSGVNGPLVIL--EKVKFPRYNEIVNLTL------PDGTVRQGQVLEIRGDRAIVQVF 80 V V GP+V + E P + + +V GD + + Sbjct: 14 GRVIQVMGPVVDVKFENGHLPAIYNALKIQHKARNENEVDIDLTLEVALHLGDDTVRTIA 73 Query: 81 EGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYL-DINGSPI 139 ++ ++ V TG + +PV E LGR+F+ G PID + A+ I+ Sbjct: 74 MASTDGLIRGMEVIDTGAPISVPVGEVTLGRVFNVLGEPIDLEGDIPADARRDPIHRPAP 133 Query: 140 NPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKD 199 E++ TG+ +D + +G KI +F +G+ + ++ Sbjct: 134 KFEELATEVEILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELIH------NIAQ 187 Query: 200 VHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLA 259 H G VFA +G + +++G + +T++ N+P R+ Sbjct: 188 EHGG-----ISVFAGVGERTREGNDLYHEMKDSGVISKTAMVFGQMNEPPGARMRVALTG 242 Query: 260 LTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERA 319 LT AEY + + VL + ++ + A EVSA +P GY + T++ + ER Sbjct: 243 LTMAEYFRDEQGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERI 302 Query: 320 GRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSL 379 GSIT I + +P DD T P P T + ++R+L GIYP ++ L S Sbjct: 303 --TSTAKGSITSIQAIYVPADDYTDPAPATTFSHLDATTNLERKLAEMGIYPAVDPLAST 360 Query: 380 SRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKF 439 SR A+ + ++H V+ ++ K+ + A++G + LS EDKL + + Sbjct: 361 SR----ALAPEIVGEEHYQVARKVQQTLQRYKELQDIIAILGMDELSDEDKLVVHRARRI 416 Query: 440 EKTFITQGAY 449 + F++Q + Sbjct: 417 Q-FFLSQNFH 425 >4Q4L-A nrPDB Length = 485 Score = 431 bits (1107), Expect = e-121, Method: Composition-based stats. Identities = 104/438 (23%), Positives = 190/438 (43%), Gaps = 24/438 (5%) Query: 11 INKKAVEQGFNVKPRLNYNTVSGVNGPLVILEKVKFPR--YNEIVNLTLPDGTVRQGQVL 68 + + G L + G ++ V+FPR +I + + +G+ +V Sbjct: 12 LEAQTQGPGSMSTAALVEGKIVQCIGAVI---DVEFPRESMPKIYDALILEGSELTLEVQ 68 Query: 69 EIRGDRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFA 128 + GD + + G S + V+ TG + +PV + LGRI D GRPID + + Sbjct: 69 QQLGDGVVRTICLGASDGLRRGVVVKNTGNPISVPVGKPTLGRIMDVLGRPIDEAGPIES 128 Query: 129 EDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQIC 188 E+ I+ E++ TG+ ID + A+G K+ +F +G+ Sbjct: 129 ENKRSIHQKAPAFDELSPSTELLETGIKVIDLICPFAKGGKVGLFGGAGVGKTV------ 182 Query: 189 RQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDP 248 L+ H G+ VFA +G F + +++ L++ +L N+P Sbjct: 183 NMMELINNIAKEHGGYS-----VFAGVGERTREGNDFYHEMKDSNVLDKVALVYGQMNEP 237 Query: 249 TIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYM 308 R+ LT AE+ + VL + ++ + A EVSA +P GY + Sbjct: 238 PGNRLRVALTGLTMAEHFRDE-GLDVLFFVDNIYRFTLAGTEVSALLGRMPSAVGYQPTL 296 Query: 309 YTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKG 368 ++ + ER + GSIT + + +P DD+T P P T + + + R + + G Sbjct: 297 AEEMGKLQERI--TSTKKGSITSVQAVYVPADDLTDPSPATTFGHLDATVVLSRDIASLG 354 Query: 369 IYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIE 428 IYP ++ L S SR + + ++H ++ ++ K+ + A++G + LS E Sbjct: 355 IYPAVDPLDSTSRQIDPNV----IGEEHYSITRRVQQTLQRYKELRDIIAILGMDELSPE 410 Query: 429 DKLSLEFLEKFEKTFITQ 446 DKLS+ K ++ F++Q Sbjct: 411 DKLSVARARKIQR-FLSQ 427 >2XND-D nrPDB Length = 467 Score = 429 bits (1102), Expect = e-120, Method: Composition-based stats. Identities = 107/427 (25%), Positives = 184/427 (43%), Gaps = 30/427 (7%) Query: 29 NTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQG--QVLEIRGDRAIVQV-FEGTSG 85 + V G +V ++ + I+N G + +V + G+ + + +GT G Sbjct: 3 GRIVAVIGAVVDVQFDEG--LPPILNALEVQGRETRLVLEVAQHLGESTVRTIAMDGTEG 60 Query: 86 IDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARI 145 + V+ V +G +RIPV + LGRI + G PID + + + I+ Sbjct: 61 L-VRGQKVLDSGAPIRIPVGPETLGRIMNVIGEPIDERGPIKTKQFAAIHAEAPEFVEMS 119 Query: 146 YPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHE 205 +E++ TG+ +D + A+G KI +F +G+ + ++ H G+ Sbjct: 120 VEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELIN------NVAKAHGGYS 173 Query: 206 ENFSIVFAAMGVNLETARFFKQDFEENGSL------ERTSLFLNLANDPTIERIITPRLA 259 VFA +G + E+G + + +L N+P R Sbjct: 174 -----VFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTG 228 Query: 260 LTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERA 319 LT AEY Q + VL + ++ + A EVSA +P GY + TD+ T+ ER Sbjct: 229 LTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERI 288 Query: 320 GRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSL 379 + GSIT + + +P DD+T P P T + + R + GIYP ++ L S Sbjct: 289 --TTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDST 346 Query: 380 SRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKF 439 SR+M I +H DV+ + K + A++G + LS EDKL++ K Sbjct: 347 SRIMDPNI----VGSEHYDVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKI 402 Query: 440 EKTFITQ 446 ++ F++Q Sbjct: 403 QR-FLSQ 408 >2W6I-D nrPDB Length = 528 Score = 428 bits (1099), Expect = e-120, Method: Composition-based stats. Identities = 107/427 (25%), Positives = 184/427 (43%), Gaps = 30/427 (7%) Query: 29 NTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQG--QVLEIRGDRAIVQV-FEGTSG 85 + V G +V ++ + I+N G + +V + G+ + + +GT G Sbjct: 61 GRIVAVIGAVVDVQFDEG--LPPILNALEVQGRETRLVLEVAQHLGESTVRTIAMDGTEG 118 Query: 86 IDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARI 145 + V+ V +G +RIPV + LGRI + G PID + + + I+ Sbjct: 119 L-VRGQKVLDSGAPIRIPVGPETLGRIMNVIGEPIDERGPIKTKQFAAIHAEAPEFVEMS 177 Query: 146 YPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHE 205 +E++ TG+ +D + A+G KI +F +G+ + ++ H G+ Sbjct: 178 VEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELIN------NVAKAHGGYS 231 Query: 206 ENFSIVFAAMGVNLETARFFKQDFEENGSL------ERTSLFLNLANDPTIERIITPRLA 259 VFA +G + E+G + + +L N+P R Sbjct: 232 -----VFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTG 286 Query: 260 LTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERA 319 LT AEY Q + VL + ++ + A EVSA +P GY + TD+ T+ ER Sbjct: 287 LTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERI 346 Query: 320 GRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSL 379 + GSIT + + +P DD+T P P T + + R + GIYP ++ L S Sbjct: 347 --TTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDST 404 Query: 380 SRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKF 439 SR+M I +H DV+ + K + A++G + LS EDKL++ K Sbjct: 405 SRIMDPNI----VGSEHYDVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKI 460 Query: 440 EKTFITQ 446 ++ F++Q Sbjct: 461 QR-FLSQ 466 >6FOC-D nrPDB Length = 475 Score = 423 bits (1087), Expect = e-118, Method: Composition-based stats. Identities = 96/428 (22%), Positives = 178/428 (41%), Gaps = 23/428 (5%) Query: 25 RLNYNTVSGVNGPLVILE--KVKFPRYNEIVNLTLPDGTVRQGQVLEIR---GDRAIVQV 79 V + GP+V +E + P ++ + G + + LE+ GD + + Sbjct: 6 EKTAGRVVRITGPVVDVEFPRGSVPELFNALHAEITFGALAKTLTLEVAQHLGDSLVRCI 65 Query: 80 FEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPI 139 + V+ V TG S+ +PV + + G +F+ G +D+ ++ I+ P Sbjct: 66 SMQPTDGLVRGVEVTDTGASISVPVGDGVKGHVFNALGDCLDDPGYGKDFEHWSIHRKPP 125 Query: 140 NPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKD 199 EM+ TG+ +D + RG KI +F +G+ + ++ + Sbjct: 126 AFSDLEPRTEMLETGLKVVDLLTPYVRGGKIALFGGAGVGKTVLIQEMINRIA------- 178 Query: 200 VHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLA 259 + VFA +G + + L+ T+L ++P R+ A Sbjct: 179 ----RNFGGTSVFAGVGERTREGNDLWVELADANVLKDTALVFGQMDEPPGTRMRVALSA 234 Query: 260 LTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERA 319 LT AE+ + + VL + ++ + A EVS +P GY + ++ + ER Sbjct: 235 LTMAEFFRDEQGQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERI 294 Query: 320 GRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSL 379 GR SIT + + +P DD T P P T + + R + +KGI+P ++ L S Sbjct: 295 TSTRGR--SITSMQAVYVPADDYTDPAPATTFAHLDATTELSRAVFSKGIFPAVDPLASS 352 Query: 380 SRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKF 439 S ++ AI +H V+ ++ KD + A++G + LS EDK + + Sbjct: 353 STILDPAI----VGDEHYRVAQEVIRILQRYKDLQDIIAILGIDELSEEDKQLVNRARRI 408 Query: 440 EKTFITQG 447 E+ F++Q Sbjct: 409 ER-FLSQN 415 >5CDF-E nrPDB Length = 474 Score = 422 bits (1084), Expect = e-118, Method: Composition-based stats. Identities = 104/426 (24%), Positives = 184/426 (43%), Gaps = 27/426 (6%) Query: 29 NTVSGVNGPLVILE-KVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGID 87 ++ V G +V ++ + P + +G +V + G+ + + + Sbjct: 6 GKITQVIGAVVDVQFDGQLPAILNALETE-NNGKRLVLEVAQHLGENTVRTIAMDATEGL 64 Query: 88 VKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYP 147 V+ V+ TG + +PV + LGRI + G P+D G V A I+ + A+ Sbjct: 65 VRGLPVKDTGGPIMVPVGDATLGRILNVVGEPVDEGGPVEATQTRAIHQQAPDFAAQATA 124 Query: 148 EEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEEN 207 E++ TG+ ID + ++G KI +F +G+ + ++ VH G+ Sbjct: 125 SEILVTGIKVIDLLAPYSKGGKIGLFGGAGVGKTVLIMELIN------NIAKVHSGYS-- 176 Query: 208 FSIVFAAMGVNLETARFFKQDFEENGSLE-------RTSLFLNLANDPTIERIITPRLAL 260 VFA +G + E+G ++ + +L N+P R+ L Sbjct: 177 ---VFAGVGERTREGNDLYHEMVESGVIKPDDLSKSQVALVYGQMNEPPGARMRVALTGL 233 Query: 261 TTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAG 320 T AE T VL + ++ + A EVSA +P GY + TD+ + ER Sbjct: 234 TVAEQFRDATGTDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGAMQERI- 292 Query: 321 RVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLS 380 +NGSIT I + +P DD+T P P T + + R + GIYP ++ L S S Sbjct: 293 -TSTKNGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRAISELGIYPAVDPLDSNS 351 Query: 381 RLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFE 440 R++ A+ ++H V+ + K + A++G + LS EDKL++ K + Sbjct: 352 RILDPAV----VGEEHYQVARDVQGILQKYKSLQDIIAILGMDELSEEDKLTVARARKIQ 407 Query: 441 KTFITQ 446 + F++Q Sbjct: 408 R-FLSQ 412 >2W6E-A nrPDB Length = 553 Score = 420 bits (1079), Expect = e-118, Method: Composition-based stats. Identities = 109/463 (23%), Positives = 197/463 (42%), Gaps = 28/463 (6%) Query: 29 NTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGIDV 88 V + + + ++ + E+V + +G L + D V VF G + Sbjct: 72 GRVLSIGDGIARVHGLRNVQAEEMVEFSSG----LKGMSLNLEPDNVGVVVF-GNDKLIK 126 Query: 89 KKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPE 148 + V+ TG + +PV E++LGR+ D G ID + ++ + RI Sbjct: 127 EGDIVKRTGAIVDVPVGEELLGRVVDALGNAIDGKGPIGSKARRRVGLKAPGIIPRISVR 186 Query: 149 EMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENF 208 E + TG+ A+D++ I RGQ+ I IA D ++ Sbjct: 187 EPMQTGIKAVDSLVPIGRGQRELIIGDRQTGKTSIAIDTIINQKRFNDGTD----EKKKL 242 Query: 209 SIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAY 268 ++ A+G T + + +++ T + A+D + + P + EY Sbjct: 243 YCIYVAIGQKRSTVAQLVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCSMGEYFRD 302 Query: 269 QTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEG--RN 326 +H L I D+S A A R++S PGR YPG ++ S + ERA ++ Sbjct: 303 -NGKHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDAFGG 361 Query: 327 GSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSA 386 GS+T +P++ D++ IP IT+GQIF++ +L KGI P INV S+SR+ +A Sbjct: 362 GSLTALPVIETQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAA 421 Query: 387 IGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEK--TFI 444 M + V+ + + A ++ AA A G + D + + L + + + Sbjct: 422 QTRAMKQ-----VAGTMKLELAQYREVAAF-AQFGSDL----DAATQQLLSRGVRLTELL 471 Query: 445 TQGAYEDRTVFESLDQAWSLLRIYPKEMLNRISPKILDEFYDR 487 QG Y + E + ++ +R Y L+++ P + +F + Sbjct: 472 KQGQYSPMAIEEQVAVIYAGVRGY----LDKLEPSKITKFENA 510 >2XND-A nrPDB Length = 492 Score = 418 bits (1075), Expect = e-117, Method: Composition-based stats. Identities = 109/463 (23%), Positives = 197/463 (42%), Gaps = 28/463 (6%) Query: 29 NTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGIDV 88 V + + + ++ + E+V + +G L + D V VF G + Sbjct: 11 GRVLSIGDGIARVHGLRNVQAEEMVEFSSG----LKGMSLNLEPDNVGVVVF-GNDKLIK 65 Query: 89 KKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPE 148 + V+ TG + +PV E++LGR+ D G ID + ++ + RI Sbjct: 66 EGDIVKRTGAIVDVPVGEELLGRVVDALGNAIDGKGPIGSKARRRVGLKAPGIIPRISVR 125 Query: 149 EMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENF 208 E + TG+ A+D++ I RGQ+ I IA D ++ Sbjct: 126 EPMQTGIKAVDSLVPIGRGQRELIIGDRQTGKTSIAIDTIINQKRFNDGTD----EKKKL 181 Query: 209 SIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAY 268 ++ A+G T + + +++ T + A+D + + P + EY Sbjct: 182 YCIYVAIGQKRSTVAQLVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCSMGEYFRD 241 Query: 269 QTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEG--RN 326 +H L I D+S A A R++S PGR YPG ++ S + ERA ++ Sbjct: 242 -NGKHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDAFGG 300 Query: 327 GSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSA 386 GS+T +P++ D++ IP IT+GQIF++ +L KGI P INV S+SR+ +A Sbjct: 301 GSLTALPVIETQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAA 360 Query: 387 IGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEK--TFI 444 M + V+ + + A ++ AA A G + D + + L + + + Sbjct: 361 QTRAMKQ-----VAGTMKLELAQYREVAAF-AQFGSDL----DAATQQLLSRGVRLTELL 410 Query: 445 TQGAYEDRTVFESLDQAWSLLRIYPKEMLNRISPKILDEFYDR 487 QG Y + E + ++ +R Y L+++ P + +F + Sbjct: 411 KQGQYSPMAIEEQVAVIYAGVRGY----LDKLEPSKITKFENA 449 >5T4O-D nrPDB Length = 471 Score = 412 bits (1059), Expect = e-115, Method: Composition-based stats. Identities = 99/423 (23%), Positives = 186/423 (43%), Gaps = 22/423 (5%) Query: 29 NTVSGVNGPLVILE--KVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGI 86 + V G +V +E + PR + + + + + +V + G + + G+S Sbjct: 15 GKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVL-EVQQQLGGGIVRTIAMGSSDG 73 Query: 87 DVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIY 146 + V+ + +PV + LGRI + G P+D ++ E+ I+ + + Sbjct: 74 LRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSN 133 Query: 147 PEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEE 206 +E++ TG+ ID M A+G K+ +F +G+ L+R H G+ Sbjct: 134 SQELLETGIKVIDLMAPFAKGGKVGLFGGAGVGKTV------NMMELIRNIAIEHSGYS- 186 Query: 207 NFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYL 266 VFA +G F + ++ +++ SL N+P R+ LT AE Sbjct: 187 ----VFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKF 242 Query: 267 AYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRN 326 + R VL + ++ Y A EVSA +P GY + ++ + ER + Sbjct: 243 RDE-GRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERI--TSTKT 299 Query: 327 GSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSA 386 GSIT + + +P DD+T P P T + + + RQ+ + GIYP ++ L S SR + Sbjct: 300 GSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPL 359 Query: 387 IGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQ 446 + ++H D + + + ++ + A++G + LS EDKL + K ++ F++Q Sbjct: 360 V----VGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQR-FLSQ 414 Query: 447 GAY 449 + Sbjct: 415 PFF 417 >5HKK-A nrPDB Length = 502 Score = 405 bits (1041), Expect = e-113, Method: Composition-based stats. Identities = 127/527 (24%), Positives = 219/527 (41%), Gaps = 47/527 (8%) Query: 1 MVLSDKELFAINKKAVEQGFNVKPRLNYNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDG 60 M + +E+ A+ KK +E + TV V + + ++ E++ Sbjct: 1 MSIRPEEISALIKKQIENYEADLEVVEVGTVIQVGDGIARVHGLEKVMAGELLEFENG-- 58 Query: 61 TVRQGQVLEIRGDRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPI 120 G + D V + + I + T V+ TG + +PV E +LGR+ + G+P+ Sbjct: 59 --VMGMAQNLEEDNVGVVILGPYTEIR-EGTQVKRTGRIMEVPVGEALLGRVVNPLGQPL 115 Query: 121 DNGPKVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPH 180 D + +Y I R E + TG+ AID+M I RGQ+ I Sbjct: 116 DGRGPIETAEYRPIESPAPGVMDRKSVHEPLQTGIKAIDSMIPIGRGQRELIIGDRQTGK 175 Query: 181 NEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSL 240 IA + ++ ++ A+G T + ++ +L+ T + Sbjct: 176 TTIAIDTI------------INQKGQDVICIYVAIGQKQSTVAGVVETLRQHDALDYTIV 223 Query: 241 FLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPG 300 A++P + P EY Y+ +H L + D+S A A RE+S PG Sbjct: 224 VTASASEPAPLLYLAPYAGCAMGEYFMYK-GKHALVVYDDLSKQAAAYRELSLLLRRPPG 282 Query: 301 RRGYPGYMYTDLSTIYERAGRVEGRN--GSITQIPILTMPNDDITHPIPDLTGYITEGQI 358 R YPG ++ S + ERA ++ GS+T +P + D++ IP IT+GQI Sbjct: 283 REAYPGDVFYLHSRLLERAAKLSDEKGGGSLTALPFIETQAGDVSAYIPTNVISITDGQI 342 Query: 359 FVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKA 418 F++ L G+ P +NV S+SR+ +A + M + V+ L A ++ A A Sbjct: 343 FLESDLFYSGVRPAVNVGISVSRVGGAAQIKAMKK-----VAGTLRLDLAQYRELQAF-A 396 Query: 419 VVGEEALSIEDKLSLEFLEKFEK--TFITQGAYEDRTVFESLDQAWSLLRIY----PKEM 472 G + DK + L + E+ + Q ++ V E + +++ + P E Sbjct: 397 QFGSDL----DKATQAKLNRGERTVEILKQDEHKPMPVEEQVISIYAVTNGFMDDIPVED 452 Query: 473 LNRISPKILDEFYDRARDDADEDE-----EDPDTRSSGKKKDASQEE 514 + R ++L + RA D+ D E PDT K+ DA+ EE Sbjct: 453 VRRFEEELLS--FMRANKDSLLDHIRQTGELPDT----KELDAAIEE 493 >6F5D-D nrPDB Length = 498 Score = 401 bits (1030), Expect = e-112, Method: Composition-based stats. Identities = 103/426 (24%), Positives = 174/426 (40%), Gaps = 26/426 (6%) Query: 29 NTVSGVNGPLVILEKVKF-PRYNEIVNLTLPDGTV--RQGQVLEIRGDRAIVQVFEGTSG 85 VS V G +V + P +++ G ++++ + T+ Sbjct: 14 GHVSQVIGAVVDVHFADGVPPVLTALDVVDKLGRDEPLTLEIVQHLDAHTGRCIAMQTTD 73 Query: 86 IDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARI 145 + K V TG ++ +PV + LGRIF+ G ID V + + I+ + Sbjct: 74 LLKLKAKVVSTGGNISVPVGRETLGRIFNVLGDAIDQRGPVGEKLRMPIHAVAPKLADQA 133 Query: 146 YPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHE 205 + +++TG+ ID + +G KI +F +G+ I ++ H G Sbjct: 134 AEDAVLTTGIKVIDLILPYCKGGKIGLFGGAGVGKTVIIMELIN------NVAKGHGGFS 187 Query: 206 ENFSIVFAAMGVNLETARFFKQDFEENGSLE-----RTSLFLNLANDPTIERIITPRLAL 260 VFA +G + ++ ++ + L N+P R + AL Sbjct: 188 -----VFAGVGERTREGTDLYLEMMQSKVIDLKGESKCVLVYGQMNEPPGARARVAQSAL 242 Query: 261 TTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAG 320 T AEY + VL + ++ + A EVSA +P GY + DL + ER Sbjct: 243 TMAEYFRDVEGQDVLLFIDNIFRFTQANSEVSALLGRIPAAVGYQPTLAEDLGQLQERI- 301 Query: 321 RVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLS 380 GSIT + + +P DDIT P P T + +DR + GIYP +N L S Sbjct: 302 -TSTTKGSITSVQAVYVPADDITDPAPATTFSHLDATTVLDRAVAESGIYPAVNPLECAS 360 Query: 381 RLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFE 440 R+M + DH +V+ + ++ + AV+G + LS EDKL ++ K Sbjct: 361 RIMDPDVIS----VDHYNVAQDVVQMLTKYRELQDIIAVLGIDELSEEDKLIVDRARKLV 416 Query: 441 KTFITQ 446 K F++Q Sbjct: 417 K-FLSQ 421 >5LQZ-A nrPDB Length = 510 Score = 397 bits (1020), Expect = e-111, Method: Composition-based stats. Identities = 109/458 (23%), Positives = 193/458 (42%), Gaps = 24/458 (5%) Query: 29 NTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGIDV 88 V V + + + + E+V +G L + + + +F + Sbjct: 31 GRVLSVGDGIARVFGLNNCQAEELVEFASG----VKGMALNLEPGQVGIVLFGSDREVKE 86 Query: 89 KKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPE 148 + V+ TG+ + +P+ MLGR+ D G PID + A Y R Sbjct: 87 GE-IVKRTGKIVDVPIGPGMLGRVVDALGNPIDGKGPIEATGYAIAQLKAPGILPRRSVF 145 Query: 149 EMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENF 208 E + TG+ A+D + I RGQ+ I +A L + + + + Sbjct: 146 EPMQTGLKAVDALVPIGRGQRELIIGDRQTGKTAVALDTI----LNQKRWNDGNDESKKL 201 Query: 209 SIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAY 268 V+ A+G T Q E+N +++ + + A++ + + P A AE+ Sbjct: 202 YCVYVAVGQKRSTVAQLVQTLEQNDAMKYSIVVAATASEAAPLQYLAPFTACAIAEWFRD 261 Query: 269 QTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEG--RN 326 +H L + D+S A A R++S PGR YPG ++ S + ERA ++ Sbjct: 262 -NGKHALIVYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSDANGG 320 Query: 327 GSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSA 386 GS+T +P++ D++ IP IT+GQIF++ +L KGI P INV S+SR+ +A Sbjct: 321 GSLTALPVIETQGGDVSAYIPTNVISITDGQIFLEAELFYKGIRPAINVGLSVSRVGSAA 380 Query: 387 IGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQ 446 + M + V+ L A ++ AA A G + L K +L E+ + + Q Sbjct: 381 QVKAMKQ-----VAGSLKLFLAQYREVAAF-AQFGSD-LDASTKQTLSRGERLTQ-LLKQ 432 Query: 447 GAYEDRTVFESLDQAWSLLRIYPKEMLNRISPKILDEF 484 Y + E + ++ + + L+ I + + EF Sbjct: 433 KQYSPQASEEQVPVIYAGVNGF----LDNIPIERIPEF 466 >3OFN-A nrPDB Length = 510 Score = 396 bits (1016), Expect = e-110, Method: Composition-based stats. Identities = 109/470 (23%), Positives = 197/470 (41%), Gaps = 25/470 (5%) Query: 18 QGFNVKPRLN-YNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAI 76 +G + + LN V V + + + + E+V + +G L + + Sbjct: 19 KGVSDEANLNETGRVLAVGDGIARVFGLNNIQAEELVEFSSG----VKGMALILEPGQVG 74 Query: 77 VQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDING 136 + +F G+ + + V+ TG + +PV +LGR+ D G PID + A Sbjct: 75 IVLF-GSDRLVKEGELVKRTGNIVDVPVGPGLLGRVVDALGNPIDGKGPIDAAGRSRAQV 133 Query: 137 SPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRP 196 R E + TG+ A+D + I RGQ+ I +A L + Sbjct: 134 KAPGILPRRSVHEPVQTGLKAVDALVPIGRGQRELIIGDRQTGKTAVALDTI----LNQK 189 Query: 197 TKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITP 256 + + V+ A+G T Q E++ +++ + + A++ + + P Sbjct: 190 RWNNGSDESKKLYCVYVAVGQKRSTVAQLVQTLEQHDAMKYSIIVAATASEAAPLQYLAP 249 Query: 257 RLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIY 316 A + E+ +H L + D+S A A R++S PGR YPG ++ S + Sbjct: 250 FTAASIGEWFRD-NGKHALIVYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLL 308 Query: 317 ERAGRVEGRN--GSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPIN 374 ERA ++ + GS+T +P++ D++ IP IT+GQIF++ +L KGI P IN Sbjct: 309 ERAAKLSEKEGSGSLTALPVIETQGGDVSAYIPTNVISITDGQIFLEAELFYKGIRPAIN 368 Query: 375 VLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLE 434 V S+SR+ +A + + + V+ L A ++ AA A G + L K +L Sbjct: 369 VGLSVSRVGSAAQVKALKQ-----VAGSLKLFLAQYREVAAF-AQFGSD-LDASTKQTLV 421 Query: 435 FLEKFEKTFITQGAYEDRTVFESLDQAWSLLRIYPKEMLNRISPKILDEF 484 E+ + + Q Y E + ++ + L+ I + EF Sbjct: 422 RGERLTQ-LLKQNQYSPLATEEQVPLIYAGV----NGHLDGIELSRIGEF 466 >6N2Y-A nrPDB Length = 502 Score = 392 bits (1008), Expect = e-109, Method: Composition-based stats. Identities = 114/488 (23%), Positives = 198/488 (40%), Gaps = 36/488 (7%) Query: 1 MVLSDKELFAINKKAVEQGFNVKPRLNYNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDG 60 M + +E+ A+ K+ +E + + TV V + + E+V Sbjct: 1 MSIRAEEISALIKQQIENYESQIQVSDVGTVIQVGDGIARAHGLDNVMSGELVEFANG-- 58 Query: 61 TVRQGQVLEIRGDRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPI 120 G L + + + + +GI V TG + +PV E ++GR+ + G+P+ Sbjct: 59 --VMGMALNLEENNVGIVILGPYTGIKEGD-EVRRTGRIMEVPVGEALIGRVVNPLGQPV 115 Query: 121 DNGPKVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPH 180 D V + I R E + TG+ AID + I RGQ+ I Sbjct: 116 DGLGPVETTETRPIESPAPGVMDRRSVHEPLQTGIKAIDALVPIGRGQRELIIGDRQTGK 175 Query: 181 NEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSL 240 +A + ++N ++ A+G T R + ++G+L+ T + Sbjct: 176 TSVAIDTI------------INQKDQNMISIYVAIGQKESTVRTVVETLRKHGALDYTIV 223 Query: 241 FLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPG 300 A+ P + P + EY Y+ +HVL + D+S A A RE+S PG Sbjct: 224 VTASASQPAPLLFLAPYAGVAMGEYFMYK-GKHVLVVYDDLSKQAAAYRELSLLLRRPPG 282 Query: 301 RRGYPGYMYTDLSTIYERAGRVEGRN--GSITQIPILTMPNDDITHPIPDLTGYITEGQI 358 R YPG ++ S + ERA ++ GS+T +P + DI+ IP IT+GQI Sbjct: 283 REAYPGDIFYLHSRLLERAAKLSDAKGGGSLTALPFVETQAGDISAYIPTNVISITDGQI 342 Query: 359 FVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKA 418 F+ L G+ P IN S+SR+ +A + M + V+ L A ++ A A Sbjct: 343 FLQSDLFFSGVRPAINAGLSVSRVGGAAQIKAMKK-----VAGTLRLDLAAYRELEAF-A 396 Query: 419 VVGEEALSIEDKLSLEFLEKFEK--TFITQGAYEDRTVFESLDQAWSLLRIY----PKEM 472 G + DK + L + + + Q ++ V + + ++L R + P E Sbjct: 397 QFGSDL----DKATQAKLARGARTVEVLKQDLHQPIPVEKQVLIIYALTRGFLDDIPVED 452 Query: 473 LNRISPKI 480 + R + Sbjct: 453 VRRFEKEF 460 >5FL7-A nrPDB Length = 536 Score = 392 bits (1006), Expect = e-109, Method: Composition-based stats. Identities = 110/479 (22%), Positives = 197/479 (41%), Gaps = 25/479 (5%) Query: 19 GFNVKPRLN-YNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIV 77 G + + LN V V + + + + E+V +G L + + + Sbjct: 44 GVSGEANLNETGRVLSVGDGIARVFGLNNIQAEELVEFASG----VKGMALNLEAGQVGI 99 Query: 78 QVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGS 137 +F G+ + + TV+ +G + +PV +LGR+ D G PID + E + Sbjct: 100 VLF-GSDRLVKEGETVKRSGSIVDVPVGPALLGRVVDALGNPIDGKGPIETEFRIRAQVK 158 Query: 138 PINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPT 197 R E + TG+ A+D + I RGQ+ I +IA L + Sbjct: 159 APGILPRTSVNEPMQTGLKAVDALVPIGRGQRELIIGDRQTGKTQIAIDTI----LNQKR 214 Query: 198 KDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPR 257 + ++ V+ A+G T Q E + +L+ + + A++ + + P Sbjct: 215 WNYGQDEKKKLYCVYVAVGQKRSTVAQLVQTLEHHDALKYSIIVAATASEAAPLQYLAPF 274 Query: 258 LALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYE 317 E+ + L + D+S A A R++S PGR YPG ++ S + E Sbjct: 275 TGTAMGEWFRD-NGKGALIVFDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLE 333 Query: 318 RAGRVEGR--NGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINV 375 RA ++ R GS+T +PI+ D++ IP IT+GQIF++ +L KGI P INV Sbjct: 334 RAAKMNEREGGGSLTALPIIETQGGDVSAYIPTNVISITDGQIFLEAELFYKGIRPAINV 393 Query: 376 LPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEF 435 S+SR+ +A + M + V+ L A ++ AA A G + L K +L Sbjct: 394 GLSVSRVGSAAQVKAMKQ-----VAGSLKLFLAQYREVAAF-AQFGSD-LDASTKQTLTR 446 Query: 436 LEKFEKTFITQGAYEDRTVFESLDQAWSLLRIY----PKEMLNRISPKILDEFYDRARD 490 E+ + Q + E + ++ + Y P + + + + + + D Sbjct: 447 GERL-TLLLKQKQASPMSSEEMVPLIYAGVNGYIDNIPVKQVEKFEAEFVSYLHANESD 504 >5DN6-A nrPDB Length = 511 Score = 391 bits (1005), Expect = e-109, Method: Composition-based stats. Identities = 118/458 (25%), Positives = 194/458 (42%), Gaps = 21/458 (4%) Query: 59 DGTVRQGQVLEIRGDRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGR 118 G +R G VL + D V +F I TV+ TG + +P +++LGR+ D G Sbjct: 56 PGGIR-GMVLNLETDNVGVVIFGDDRDIKEGD-TVKRTGAIVEVPAGKELLGRVVDALGN 113 Query: 119 PIDNGPKVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGL 178 PID + A + + R E ++TG+ ++D M + RGQ+ I Sbjct: 114 PIDGKGPLNASERRIADVKAPGIMPRKSVHEPMATGLKSVDAMIPVGRGQRELIIGDRQT 173 Query: 179 PHNEIAAQIC-RQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLER 237 IA QA D + ++ A+G T + EE G++ Sbjct: 174 GKTAIALDTILNQANYNGREADGM----KTLHCIYVAVGQKRSTVAQLVKKLEETGAMAY 229 Query: 238 TSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREE 297 T++ A+DP + + P A EY L I D+S A A R++S Sbjct: 230 TTVVAATASDPAPMQYLAPYSATAMGEYFRD-NGMDALIIYDDLSKQAVAYRQMSLLLRR 288 Query: 298 VPGRRGYPGYMYTDLSTIYERAGRVEGRN--GSITQIPILTMPNDDITHPIPDLTGYITE 355 PGR YPG ++ S + ER+ ++ N GS+T +PI+ D++ IP IT+ Sbjct: 289 PPGREAYPGDVFYLHSRLLERSAKLNEANGAGSLTALPIIETQAGDVSAYIPTNVISITD 348 Query: 356 GQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAA 415 GQIF++ +L +GI P +N S+SR+ +A + M V+ + + A ++ AA Sbjct: 349 GQIFLETELFFQGIRPAVNTGLSVSRVGSAAQTKAM-----KSVAGPVKLELAQYREMAA 403 Query: 416 MKAVVGEEALSIEDKLSLEFLEKFEKTFITQGAYEDRTVFESLDQAWSLLRIYPKEMLNR 475 A G + + KL E + Q Y T E + ++ + Y + R Sbjct: 404 F-AQFGSDLDAATQKLLNRGARLTE--LMKQPQYSPLTNAEIVIVIYAGTKGYLDGIPVR 460 Query: 476 ISPKI---LDEFYDRARDDADEDEEDPDTRSSGKKKDA 510 K L ++ + D ED D + +G+ +DA Sbjct: 461 DVTKWEHGLLQYLRNQKADLLEDMTKNDRKVAGELEDA 498 >2R9V-A nrPDB Length = 515 Score = 389 bits (999), Expect = e-108, Method: Composition-based stats. Identities = 112/486 (23%), Positives = 198/486 (40%), Gaps = 31/486 (6%) Query: 29 NTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGIDV 88 V V + + +E+V T +G + D + + I Sbjct: 41 GKVIQVGDGIARAYGLNKVMVSELVEFVE---TGVKGVAFNLEEDNVGIIILGEYKDIK- 96 Query: 89 KKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPE 148 + TV + +PV E++LGR+ + G P+D + A+++ I R + Sbjct: 97 EGHTVRRLKRIIEVPVGEELLGRVVNPLGEPLDGKGPINAKNFRPIEIKAPGVIYRKPVD 156 Query: 149 EMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENF 208 + TG+ AID+M I RGQ+ I IA + + Sbjct: 157 TPLQTGIKAIDSMIPIGRGQRELIIGDRQTGKTAIAIDTI------------INQKGQGV 204 Query: 209 SIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAY 268 ++ A+G + G++E T++ + A+DP + I P EY AY Sbjct: 205 YCIYVAIGQKKSAIARIIDKLRQYGAMEYTTVVVASASDPASLQYIAPYAGCAMGEYFAY 264 Query: 269 QTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGR--N 326 + R L + D+S +A A R++S PGR YPG ++ S + ERA R+ + Sbjct: 265 -SGRDALVVYDDLSKHAVAYRQLSLLMRRPPGREAYPGDIFYLHSRLLERAVRLNDKLGG 323 Query: 327 GSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSA 386 GS+T +PI+ +DI+ IP IT+GQI+++ L G P INV S+SR+ SA Sbjct: 324 GSLTALPIVETQANDISAYIPTNVISITDGQIYLEPGLFYAGQRPAINVGLSVSRVGGSA 383 Query: 387 IGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQ 446 + M + V+ L A ++ L + + ++ + + Q Sbjct: 384 QIKAMKQ-----VAGMLRIDLAQYRELETFAQFA--TELDPATRAQIIRGQRLME-LLKQ 435 Query: 447 GAYEDRTVFESLDQAWSLLRIY----PKEMLNRISPKILDEFYDRARDDADEDEEDPDTR 502 Y V E + ++ +R Y P E + R + L +++ +D D+ + + Sbjct: 436 EQYSPMPVEEQVVVLFAGVRGYLDDLPVEEVRRFEKEFLRFMHEKHQDILDDIKTKKELT 495 Query: 503 SSGKKK 508 S ++K Sbjct: 496 SETEEK 501 >5BO5-A nrPDB Length = 416 Score = 384 bits (987), Expect = e-107, Method: Composition-based stats. Identities = 184/434 (42%), Positives = 272/434 (62%), Gaps = 30/434 (6%) Query: 33 GVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGIDVKKTT 92 + PL+ +E ++ P E+++L + V+ ++A+ +F+ +G ++K+ Sbjct: 3 SIKPPLIAVE-LENPMLGEVIDLE-----ETKAIVIAAYENKALALLFDYYTG-EIKQ-- 53 Query: 93 VEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPEEMIS 152 + G + +I VSED +G IF+G G PI GPK + EDY DING INPYAR P E++ Sbjct: 54 INRQGNTYKIAVSEDYIGGIFNGFGEPI-KGPKPYPEDYRDINGLAINPYARKVPNEILY 112 Query: 153 TGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVF 212 TG+S+ID + + +GQKI IFS GLP +A QI R ++ +I+F Sbjct: 113 TGISSIDVAHPLLKGQKIAIFSPPGLPMERLALQIARNVA-------------KDKTIIF 159 Query: 213 AAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTER 272 AA+GV + + F +F ++ +++F++ A+ IE+I TPR+ALT AEYLA++ R Sbjct: 160 AAIGVPSDIYKMFIDEFINTKAIMNSAIFISKADSSPIEKIYTPRVALTLAEYLAFEKNR 219 Query: 273 HVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQI 332 VL ++ DM++YADALRE+S R+E+P RRGYP Y+YTDL++IYER+G GSIT I Sbjct: 220 DVLVLMLDMTNYADALREISTLRKEIPSRRGYPAYLYTDLASIYERSGLTS--KGSITLI 277 Query: 333 PILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMT 392 P+LTMP +DITH +PDLTGYITEGQ + + LH+K IYPPI++L SLSRL K+ + + Sbjct: 278 PMLTMPGNDITHVVPDLTGYITEGQYVLSQDLHSKNIYPPIDLLKSLSRLAKNGMSK--- 334 Query: 393 RKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQGAYEDR 452 H ++ L YA G +A + +VGE++LS EDK L+F E EK FI Q YE R Sbjct: 335 --KHKKYADILIKSYAKGLEARDIATIVGEDSLSKEDKAYLKFAELVEKEFIKQDYYEYR 392 Query: 453 TVFESLDQAWSLLR 466 ++ +S + S+L Sbjct: 393 SIEKSFEIIDSILS 406 >6FKI-E nrPDB Length = 507 Score = 379 bits (973), Expect = e-105, Method: Composition-based stats. Identities = 122/497 (24%), Positives = 206/497 (41%), Gaps = 38/497 (7%) Query: 26 LNYNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSG 85 +N TV V + + + E+V G L + + V + G Sbjct: 27 VNTGTVLQVGDGIARIHGLDEVMAGELVEFE----EGTIGIALNLESNNVGVVLMGD--G 80 Query: 86 IDV-KKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYAR 144 + + + ++V+ TG +IPVSE LGR+ + +PID ++ A + I +R Sbjct: 81 LMIQEGSSVKATGRIAQIPVSEAYLGRVINALAKPIDGRGEITASESRLIESPAPGIMSR 140 Query: 145 IYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGH 204 E + TG+ AID M + RGQ+ I +A + Sbjct: 141 RSVYEPLQTGLIAIDAMIPVGRGQRELIIGDRQTGKTAVATDTI------------LNQQ 188 Query: 205 EENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAE 264 +N V+ A+G + +F+E G++E T + A+ P + + P AE Sbjct: 189 GQNVICVYVAIGQKASSVAQVVTNFQERGAMEYTIVVAETADSPATLQYLAPYTGAALAE 248 Query: 265 YLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEG 324 Y Y+ ERH L I D+S A A R++S PGR YPG ++ S + ERA ++ Sbjct: 249 YFMYR-ERHTLIIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSS 307 Query: 325 --RNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRL 382 GS+T +PI+ D++ IP IT+GQIF+ L N GI P INV S+SR+ Sbjct: 308 LLGEGSMTALPIVETQAGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRV 367 Query: 383 MKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFE-- 440 +A + M + V+ +L + A + A S DK + L + + Sbjct: 368 GSAAQIKAMKK-----VAGKLKLELAQFAELEAFAQFA-----SDLDKATQNQLARGQRL 417 Query: 441 KTFITQGAYEDRTVFESLDQAWSLLRIYPKEMLNRISPKILDEFYDRARDDADEDEEDPD 500 + + Q TV E + ++ Y L+ + + ++ R ++ + Sbjct: 418 RELLKQPQSAPLTVEEQVMTIYTGTNGY----LDSLELDQVRKYLVELRTYVKTNKPEFQ 473 Query: 501 TRSSGKKKDASQEESLI 517 S K + E+L+ Sbjct: 474 EIISSTKTFTEEAEALL 490 >5T4O-A nrPDB Length = 513 Score = 375 bits (962), Expect = e-104, Method: Composition-based stats. Identities = 113/508 (22%), Positives = 200/508 (39%), Gaps = 43/508 (8%) Query: 1 MVLSDKELFAINKKAVEQGFNVKPRLNYNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDG 60 M L+ E+ + K+ + Q V N T+ V+ ++ + + E+++L Sbjct: 1 MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADAMQGEMISLP---- 56 Query: 61 TVRQGQVLEIRGDRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPI 120 R L + D V + + + V+ TG L +PV +LGR+ + G PI Sbjct: 57 GNRYAIALNLERDSVGAVVMGPYADL-AEGMKVKATGRILEVPVGRGLLGRVVNTLGAPI 115 Query: 121 DNGPKVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPH 180 D + + + + R ++ + TG A+D+M I RGQ+ I Sbjct: 116 DGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGK 175 Query: 181 NEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSL 240 +A + + ++ A+G T + EE+G+L T + Sbjct: 176 TALAIDAI------------INQRDSGIKAIYVAIGQKASTISNVVRKLEEHGALANTIV 223 Query: 241 FLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPG 300 + A++ + + P EY + E L I D+S A A R++S PG Sbjct: 224 VVATASESAALQYLAPYAGAAMGEYFRDRGE-DALIIYDDLSKQAVAYRQISLLLRRPPG 282 Query: 301 RRGYPGYMYTDLSTIYERAGRVE-------------GRNGSITQIPILTMPNDDITHPIP 347 R +PG ++ S + ERA RV G+ GS+T +PI+ D++ +P Sbjct: 283 REAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVP 342 Query: 348 DLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKY 407 IT+GQIF++ L N GI P +N S+SR+ +A + M + +S + Sbjct: 343 TNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKK-----LSGGIRTAL 397 Query: 408 AIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQGAYEDRTVFESLDQAWSLLRI 467 A ++ AA L + L+ +K + + Q Y +V + ++ R Sbjct: 398 AQYRELAAFSQFA--SDLDDATRNQLDHGQKVTE-LLKQKQYAPMSVAQQSLVLFAAERG 454 Query: 468 YPKEMLNRISPKILDEFYDRARDDADED 495 Y L + + F D D Sbjct: 455 Y----LADVELSKIGSFEAALLAYVDRD 478 >6FOC-A nrPDB Length = 548 Score = 373 bits (957), Expect = e-103, Method: Composition-based stats. Identities = 121/500 (24%), Positives = 200/500 (40%), Gaps = 31/500 (6%) Query: 24 PRLNYNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGT 83 R TV + +E + E++ G V G L + + Sbjct: 27 EREEIGTVIDAGDGIAHVEGLPSVMTQELLEF---PGGV-LGVALNLDEHSVGAVILGEF 82 Query: 84 SGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYA 143 I+ + V+ TGE L +PV + LGR+ + G+PID + AE + + Sbjct: 83 EKIEEGQ-QVKRTGEVLSVPVGDAFLGRVVNPLGQPIDGQGDIAAETRRALELQAPSVVQ 141 Query: 144 RIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDG 203 R E + TG+ AID M I RGQ+ I + L + + Sbjct: 142 RQSVSEPLQTGIKAIDAMTPIGRGQRQLIIGDRKTGKTAVCVDTI----LNQREAWLTGD 197 Query: 204 HEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTA 263 ++ V+ A+G T K+ EE G++E T++ A+D + + P Sbjct: 198 PKQQVRCVYVAIGQKGTTIASVKRALEEGGAMEYTTIVAAPASDAAGFKWLAPYTGSAIG 257 Query: 264 EYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVE 323 ++ Y +HVL + D+S ADA R +S PGR +PG ++ S + ER ++ Sbjct: 258 QHWMY-NGKHVLIVFDDLSKQADAYRAISLLLRRPPGREAFPGDVFYLHSRLLERCAKLS 316 Query: 324 G--RNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSR 381 GS+T +PI+ +DI+ IP IT+GQ F++ L N+G+ P INV S+SR Sbjct: 317 DELGGGSMTGLPIIETKANDISAFIPTNVISITDGQCFLESDLFNQGVRPAINVGVSVSR 376 Query: 382 LMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEK 441 + +A + M +V+ L + ++ A A L K L+ + + Sbjct: 377 VGGAAQIKAM-----KEVAGSLRLDLSQYRELEAFAAFA--SDLDAASKAQLDRGARLVE 429 Query: 442 TFITQGAYEDRTVFESLDQAWSLLRI----YPKEMLNRISPKILDEFYDRARDDADEDEE 497 + Q Y V E + + + P E + R ++L+ D D E Sbjct: 430 -LLKQPQYSPLAVEEQVVAIFLGTQGHLDSVPVEDVQRFESELLEHVKASHSDIFDGIRE 488 Query: 498 DPDTRSSGKKKDASQEESLI 517 KK EE L+ Sbjct: 489 T-------KKLSEEAEEKLV 501 >6F5D-A nrPDB Length = 560 Score = 363 bits (932), Expect = e-101, Method: Composition-based stats. Identities = 100/407 (24%), Positives = 170/407 (41%), Gaps = 22/407 (5%) Query: 20 FNVKPRLNY-NTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGD-RAIV 77 F + Y +++ G L+ YN I+ + + T G V + D R + Sbjct: 22 FKTTEMIGYVHSIDGTIATLIPAPGNPGVAYNTIIQIQVSPTTFAAGLVFNLEKDGRIGI 81 Query: 78 QVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLD---- 133 + + + + + V TG+ L IPV +LG++ + G + G + LD Sbjct: 82 ILMDNITEVQSGQ-KVMATGQLLHIPVGAGVLGKVVNPLGHEVPVGLVTRSRRLLDSTLG 140 Query: 134 -INGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAA-QICRQA 191 ++ N +R + TG A+DTM I RGQ+ I IA I Q Sbjct: 141 KVDTGAPNIVSRSPVNYNLLTGFKAVDTMIPIGRGQRELIVGDRQTGKTSIAVSTIINQV 200 Query: 192 GLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIE 251 + + + ++ ++G + + G+L T++ A +P Sbjct: 201 RINQQIL-----SKNAVISIYVSIGQRCSNVARIHRLLQSYGALRYTTVMAATAAEPAGL 255 Query: 252 RIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTD 311 + + P +T EY + RH L + D+S A A R++S PGR YPG ++ Sbjct: 256 QYLAPYAGVTMGEYFMNR-GRHCLCVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYL 314 Query: 312 LSTIYERAGRVE--GRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGI 369 S + ERA + GS+T +PI+ ++D+T I IT+GQI++D +L G Sbjct: 315 HSRLLERAAMLSPGKGGGSVTALPIVETLSNDVTAYIVTNVISITDGQIYLDTKLFTGGQ 374 Query: 370 YPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAM 416 P +N+ S+SR+ SA M V+ +L A + AA Sbjct: 375 RPAVNIGLSVSRVGSSAQNAAMKG-----VAGKLKGILAEYRKLAAD 416 >6NJP-A nrPDB Length = 449 Score = 359 bits (921), Expect = 2e-99, Method: Composition-based stats. Identities = 106/440 (24%), Positives = 189/440 (42%), Gaps = 39/440 (8%) Query: 18 QGFNVKPRLNY-NTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAI 76 ++ Y + + G ++ ++ R + R +V+ I D Sbjct: 27 PALSLNSSTRYEGKIINIGGTIIKA-RLPKARIGAFYKIEPSQ---RLAEVIAIDEDEVF 82 Query: 77 VQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDY-LDIN 135 + FE SG+ + + + G+ +I V + +LGR+ DG GRP+++ + + Sbjct: 83 LLPFEHVSGMYCGQW-LSYQGDEFKIRVGDALLGRLIDGIGRPMESNIVAPYLPFERSLY 141 Query: 136 GSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVR 195 P +P R ++ GV AID + + GQ+I IF+ SG+ + + IC A Sbjct: 142 AEPPDPLLRQVIDQPFILGVRAIDGLLTCGIGQRIGIFAGSGVGKSTLLGMICNGA---- 197 Query: 196 PTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIIT 255 IV A +G F ++ +L + L + ++ P +ER+ Sbjct: 198 ----------SADIIVLALIGERGREVNEFLALLPQS-TLSKCVLVVTTSDRPALERMKA 246 Query: 256 PRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTI 315 A T AEY Q ++VL ++ ++ YA A R+V A E R G+P +++ L + Sbjct: 247 AFTATTIAEYFRDQ-GKNVLLMMDSVTRYARAARDVGLASGEPDVRGGFPPSVFSSLPKL 305 Query: 316 YERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINV 375 ERAG GSIT I + + +D++ PI D I +G I + R+L + +P I++ Sbjct: 306 LERAG--PAPKGSITAIYTVLLESDNVNDPIGDEVRSILDGHIVLTRELAEENHFPAIDI 363 Query: 376 LPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYA------------IGKDAAAMKAVVGEE 423 S SR+M + + R +L A Y +G+D A KA+ + Sbjct: 364 GLSASRVMHNVVTSEHLR--AAAECKKLIATYKNVELLIRIGEYTMGQDPEADKAIKNRK 421 Query: 424 ALSIEDKLSLEFLEKFEKTF 443 + + S + + +EKT Sbjct: 422 LIQNFIQQSTKDISSYEKTI 441 >2DPY-A nrPDB Length = 438 Score = 345 bits (886), Expect = 2e-95, Method: Composition-based stats. Identities = 109/449 (24%), Positives = 187/449 (41%), Gaps = 35/449 (7%) Query: 28 YNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQ---GQVLEIRGDRAIVQVFEGTS 84 Y ++ G ++ ++ P + DG + +V+ G R + E Sbjct: 10 YGRLTRATGLVLEATGLQLP-LGATCIIERQDGPETKEVESEVVGFNGQRLFLMPLEEVE 68 Query: 85 GIDVKKTTVEFTGES------LRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSP 138 GI G ++P+ +LGR+ DG G+P+D P + + P Sbjct: 69 GILPGARVYARNGHGDGLQSGKQLPLGPALLGRVLDGGGKPLDGLPAPDTLETGALITPP 128 Query: 139 INPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTK 198 NP R E ++ TGV AI+ + ++ RGQ++ +F+ SG+ + + + R Sbjct: 129 FNPLQRTPIEHVLDTGVRAINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYT------- 181 Query: 199 DVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRL 258 IV +G + F ++ R+ + A+ + R+ Sbjct: 182 -------RADVIVVGLIGERGREVKDFIENILGPDGRARSVVIAAPADVSPLLRMQGAAY 234 Query: 259 ALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYER 318 A AE + +HVL I+ ++ YA A RE++ A E P +GYP ++ L + ER Sbjct: 235 ATRIAEDFRDR-GQHVLLIMDSLTRYAMAQREIALAIGEPPATKGYPPSVFAKLPALVER 293 Query: 319 AGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPS 378 AG GSIT + DD PI D I +G I + R+L G YP I++ S Sbjct: 294 AGNGIHGGGSITAFYTVLTEGDDQQDPIADSARAILDGHIVLSRRLAEAGHYPAIDIEAS 353 Query: 379 LSRLMKSAIGEGMTRKDHGDVS--NQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFL 436 +SR M + I T + + V QL + + +D ++ A ++ ++L Sbjct: 354 ISRAMTALI----TEQHYARVRLFKQLLSSFQRNRDLVSVGAYAKGSDPMLDKAITL--W 407 Query: 437 EKFEKTFITQGAYEDRTVFESLDQAWSLL 465 + E F+ QG +E R +E QA L+ Sbjct: 408 PQLE-AFLQQGIFE-RADWEDSLQALDLI 434 >5BN5-A nrPDB Length = 570 Score = 343 bits (880), Expect = 1e-94, Method: Composition-based stats. Identities = 105/397 (26%), Positives = 161/397 (40%), Gaps = 33/397 (8%) Query: 92 TVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPY-------AR 144 TV G RI V ++ G+I I G E +NG PI Y R Sbjct: 134 TVNENGFEHRIIVPPNVEGKI-----EEIYEGNFTIEETIAIVNGKPIKLYHEWPIRKPR 188 Query: 145 IYPEE-----MISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAG--LVRPT 197 Y E+ TG +D M IA+G + G + QI + A +V Sbjct: 189 PYKEKLDYNYPFITGTRVLDIMFPIAKGGSAAVPGPFGSGKTVLNQQIAKWADSDIVIYI 248 Query: 198 KDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPR 257 G+E M LE K + RT L N +N P R + Sbjct: 249 GCGERGNE---------MTEVLEEFPKLKDPKTGKPLMYRTILIANTSNMPIAAREASIY 299 Query: 258 LALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYE 317 L T EY Q V+ S +A+ALRE+S+ E+P GYP Y+ L+ YE Sbjct: 300 LGATIGEYFRDQ-GYSVVVNADSTSRWAEALREISSRLGEIPSEEGYPAYLLRKLAEFYE 358 Query: 318 RAGRVEGRN---GSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPIN 374 R+GRV N GS+T I ++ P D + P+ T + +D +L K YP IN Sbjct: 359 RSGRVRTLNDLEGSLTIIGAVSPPGGDFSEPVTQNTLRLVGALWALDSKLAYKRHYPAIN 418 Query: 375 VLPSLSRLMKSAIGE-GMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSL 433 L S ++ + +D ++ + +A + + ++VG +ALS +K+ L Sbjct: 419 YLISYTKQWEFVKKYFEELYEDVIEIREEFFAILKRESELMDIVSIVGPDALSDNEKIYL 478 Query: 434 EFLEKFEKTFITQGAYEDRTVFESLDQAWSLLRIYPK 470 + F+ Q A+++ + L++ L+RI K Sbjct: 479 HMGRIIREGFLQQDAFDENDSYSPLEKTIELMRIIHK 515 Score = 89.1 bits (219), Expect = 5e-18, Method: Composition-based stats. Identities = 41/123 (33%), Positives = 62/123 (50%), Gaps = 7/123 (5%) Query: 29 NTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGIDV 88 N + +NGPLVI K KF + E+V + G+V+ I D+A +QV+E T+G+ V Sbjct: 2 NRIISINGPLVIA-KGKFSIF-EVVRVGEEK---LIGEVIGIENDKAYIQVYEDTNGLKV 56 Query: 89 KKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPE 148 + V TG+ L I + +L IFDG GRP+ + + Y+ G + R Sbjct: 57 GEP-VFNTGKPLTIELGPGLLANIFDGLGRPLKDIYEKTQSIYIP-KGIDLPTLDRKKVW 114 Query: 149 EMI 151 E I Sbjct: 115 EFI 117 >2OBL-A nrPDB Length = 347 Score = 325 bits (833), Expect = 3e-89, Method: Composition-based stats. Identities = 95/358 (26%), Positives = 161/358 (44%), Gaps = 33/358 (9%) Query: 99 SLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDY-LDINGSPINPYARIYPEEMISTGVSA 157 S +I V + +LGR+ DG GRP+++ + + P +P R ++ GV A Sbjct: 2 SHKIRVGDALLGRLIDGIGRPMESNIVAPYLPFERSLYAEPPDPLLRQVIDQPFILGVRA 61 Query: 158 IDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGV 217 ID + + GQ+I IF+ SG+ + + IC A IV A +G Sbjct: 62 IDGLLTCGIGQRIGIFAGSGVGKSTLLGMICNGA--------------SADIIVLALIGE 107 Query: 218 NLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTI 277 F ++ +L + L + ++ P +ER+ A T AEY Q ++VL + Sbjct: 108 RGREVNEFLALLPQS-TLSKCVLVVTTSDRPALERMKAAFTATTIAEYFRDQ-GKNVLLM 165 Query: 278 LTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTM 337 + ++ YA A R+V A E R G+P +++ L + ERAG GSIT I + + Sbjct: 166 MDSVTRYARAARDVGLASGEPDVRGGFPPSVFSSLPKLLERAG--PAPKGSITAIYTVLL 223 Query: 338 PNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHG 397 +D++ PI D I +G I + R+L + +P I++ S SR+M + + R Sbjct: 224 ESDNVNDPIGDEVRSILDGHIVLTRELAEENHFPAIDIGLSASRVMHNVVTSEHLR--AA 281 Query: 398 DVSNQLYAKYA------------IGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTF 443 +L A Y +G+D A KA+ + + + S + + +EKT Sbjct: 282 AECKKLIATYKNPELLIRIGEYTMGQDPEADKAIKNRKLIQNFIQQSTKDISSYEKTI 339 >3MFY-A nrPDB Length = 588 Score = 314 bits (803), Expect = 8e-86, Method: Composition-based stats. Identities = 93/410 (22%), Positives = 160/410 (39%), Gaps = 42/410 (10%) Query: 99 SLRIPVSEDMLGRIFDGSGRPIDNGPKVFAE--------------DYLDINGSPINPYAR 144 +I V + G I + + +V A+ + + Sbjct: 146 VHKIMVPPGIEGEIVEIAEEGDYTIEEVIAKVKTPSGEIKELKMYQRWPVRVKRP-YKEK 204 Query: 145 IYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAG--LVRPTKDVHD 202 + PE + TG IDT A+G I +G Q+ + + +V Sbjct: 205 LPPEVPLITGQRVIDTFFPQAKGGTAAIPGPAGSGKTVTQHQLAKWSDAQVVIYIGCGER 264 Query: 203 GHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTT 262 G+E M LE K +ERT L N +N P R + +T Sbjct: 265 GNE---------MTDVLEEFPKLKDPKTGKPLMERTVLIANTSNMPVAAREASIYTGITI 315 Query: 263 AEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRV 322 AEY V + S +A+ALRE+S EE+PG GYP Y+ + L+ YERAGRV Sbjct: 316 AEYFRDM-GYDVALMADSTSRWAEALREISGRLEEMPGEEGYPAYLASKLAEFYERAGRV 374 Query: 323 EGRN-----GSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLP 377 GS++ I ++ P D + P+ T + + +D L + +P IN L Sbjct: 375 VTLGSDYRVGSVSVIGAVSPPGGDFSEPVVQNTLRVVKVFWALDADLARRRHFPAINWLT 434 Query: 378 SLSRLMKSAIGEGMTRK---DHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLE 434 S S L A+ + + + + ++ A + + +VG +AL ++ L Sbjct: 435 SYS-LYVDAVKDWWHKNIDPEWKAMRDKAMALLQKESELQEIVRIVGPDALPERERAILL 493 Query: 435 FLEKFEKTFITQGAYEDRTVFESLDQAWSLLRI----YPKEM--LNRISP 478 + ++ Q A+++ + ++ +++R+ Y K M +NR P Sbjct: 494 VARMLREDYLQQDAFDEVDTYCPPEKQVTMMRVLLNFYDKTMEAINRGVP 543 >5Y60-A nrPDB Length = 578 Score = 306 bits (783), Expect = 2e-83, Method: Composition-based stats. Identities = 89/411 (21%), Positives = 164/411 (39%), Gaps = 44/411 (10%) Query: 85 GIDVKKTTVEFT----GESLRIPVSEDMLGRIFDG-------SGRPI---DNGPKVFAED 130 G +V+ V T G + +I V D+ GR+ + P+ ++G ++ Sbjct: 126 GDEVRGGMVLGTVPEFGFTHKILVPPDVRGRVKEVKPAGEYTVEEPVVVLEDGTELKMYH 185 Query: 131 YLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQ 190 + + ++ P TG+ +D + +A G I G + + Sbjct: 186 TWPVRRARP-VQRKLDPNTPFLTGMRILDVLFPVAMGGTAAIPGPFGSGKTVTQQSLAKW 244 Query: 191 AGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEE-------NGSLERTSLFLN 243 + +V+ G +F E + RT L N Sbjct: 245 SN--------------ADVVVYVGCGERGNEMTDVLVEFPELTDPKTGGPLMHRTVLIAN 290 Query: 244 LANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRG 303 +N P R + + +T AEY Q V + S +A+ALRE+S+ EE+P G Sbjct: 291 TSNMPVAAREASIYVGVTIAEYFRDQ-GFSVALMADSTSRWAEALREISSRLEEMPAEEG 349 Query: 304 YPGYMYTDLSTIYERAGRV---EGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFV 360 YP Y+ L+ YERAG+V G G++T + ++ P D++ P+ T I + Sbjct: 350 YPPYLAARLAAFYERAGKVITLGGEEGAVTIVGAVSPPGGDMSEPVTQSTLRIVGAFWRL 409 Query: 361 DRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTR---KDHGDVSNQLYAKYAIGKDAAAMK 417 D L + +P IN S S L SA+ +D+ ++ + + + Sbjct: 410 DASLAFRRHFPAINWNGSYS-LFTSALDPWYRENVAEDYPELRDAISELLQREAGLQEIV 468 Query: 418 AVVGEEALSIEDKLSLEFLEKFEKTFITQGAYEDRTVFESLDQAWSLLRIY 468 +VG +AL ++L +E + F+ Q AY + + S+ +A+ ++++ Sbjct: 469 QLVGPDALQDAERLVIEVGRIIREDFLQQNAYHEVDAYCSMKKAYGIMKMI 519 Score = 91.8 bits (226), Expect = 7e-19, Method: Composition-based stats. Identities = 31/93 (33%), Positives = 50/93 (53%), Gaps = 4/93 (4%) Query: 29 NTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGIDV 88 + + GP VI + + R +I + +G V G+++ + GD A VQV+E TSG+ V Sbjct: 4 GVIQKIAGPAVIAKGMLGARMYDICKVG-EEGLV--GEIIRLDGDTAFVQVYEDTSGLKV 60 Query: 89 KKTTVEFTGESLRIPVSEDMLGRIFDGSGRPID 121 + V TG L + + ML I+DG RP++ Sbjct: 61 GEPVVS-TGLPLAVELGPGMLNGIYDGIQRPLE 92 >4NPH-A nrPDB Length = 351 Score = 304 bits (779), Expect = 5e-83, Method: Composition-based stats. Identities = 85/322 (26%), Positives = 148/322 (45%), Gaps = 27/322 (8%) Query: 100 LRIPVSEDMLGRIFDGSGRPIDNG--PKVFAEDYLDINGSPINPYARIYPEEMISTGVSA 157 +++PV E +LGR+ DG GRP+D P V +DY + P R + + TG+ A Sbjct: 1 MQVPVGEALLGRVIDGFGRPLDGRELPDVCWKDY---DAMPPPAMVRQPITQPLMTGIRA 57 Query: 158 IDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGV 217 ID++ + GQ++ IFSA G+ + + A +C V +G Sbjct: 58 IDSVATCGEGQRVGIFSAPGVGKSTLLAMLCNAPDADSN--------------VLVLIGE 103 Query: 218 NLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTI 277 R F + +R + + ++ P +ER+ +A T AE+ +R V+ + Sbjct: 104 RGREVREFIDFTLSEETRKRCVIVVATSDRPALERVRALFVATTIAEFFRDNGKR-VVLL 162 Query: 278 LTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTM 337 ++ YA A RE++ A E YP +++ L + ER G G GSIT + + Sbjct: 163 ADSLTRYARAAREIALAAGETAVSGEYPPGVFSALPRLLERTGM--GEKGSITAFYTVLV 220 Query: 338 PNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHG 397 DD+ P+ D + +G I + R+L +G YP I+VL +LSR+ +T +H Sbjct: 221 EGDDMNEPLADEVRSLLDGHIVLSRRLAERGHYPAIDVLATLSRVF-----PVVTSHEHR 275 Query: 398 DVSNQLYAKYAIGKDAAAMKAV 419 ++ L A+ ++ + + Sbjct: 276 QLAAILRRCLALYQEVELLIRI 297 >6O7W-C nrPDB Length = 639 Score = 297 bits (759), Expect = 1e-80, Method: Composition-based stats. Identities = 73/347 (21%), Positives = 147/347 (42%), Gaps = 32/347 (9%) Query: 138 PINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPT 197 P ++ + + TG +D + +G I A G I+ + + Sbjct: 221 PRPVTEKLSADYPLLTGQRVLDALFPCVQGGTTCIPGAFGCGKTVISQSLSK-------- 272 Query: 198 KDVHDGHEENFSIVFAAMGVNLETARFFKQDFEE---------NGSLERTSLFLNLANDP 248 + + +I++ G +F E ++RT+L N +N P Sbjct: 273 ------YSNSDAIIYVGCGERGNEMAEVLMEFPELYTEMSGTKEPIMKRTTLVANTSNMP 326 Query: 249 TIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYM 308 R + +T AEY Q ++V I S +A+ALRE+S E+P +G+P Y+ Sbjct: 327 VAAREASIYTGITLAEYFRDQ-GKNVSMIADSSSRWAEALREISGRLGEMPADQGFPAYL 385 Query: 309 YTDLSTIYERAGRV-----EGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQ 363 L++ YERAG+ R GS++ + ++ D + P+ T IT+ +D++ Sbjct: 386 GAKLASFYERAGKAVALGSPDRTGSVSIVAAVSPAGGDFSDPVTTATLGITQVFWGLDKK 445 Query: 364 LHNKGIYPPINVLPSLSRLMKSAIGEGMTRK--DHGDVSNQLYAKYAIGKDAAAMKAVVG 421 L + +P IN S S+ + + + + + +++ + ++ + +VG Sbjct: 446 LAQRKHFPSINTSVSYSK-YTNVLNKFYDSNYPEFPVLRDRMKEILSNAEELEQVVQLVG 504 Query: 422 EEALSIEDKLSLEFLEKFEKTFITQGAYEDRTVFESLDQAWSLLRIY 468 + ALS DK++L+ ++ F+ Q Y F + + + ++R + Sbjct: 505 KSALSDSDKITLDVATLIKEDFLQQNGYSTYDAFCPIWKTFDMMRAF 551 Score = 101 bits (251), Expect = 8e-22, Method: Composition-based stats. Identities = 30/93 (32%), Positives = 51/93 (54%), Gaps = 4/93 (4%) Query: 28 YNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGID 87 Y + V+GP+VI E + E+V + + G+V+ I GD+A +QV+E T+G+ Sbjct: 25 YGAIYSVSGPVVIAENMIGCAMYELVKVGHDN---LVGEVIRIDGDKATIQVYEETAGLT 81 Query: 88 VKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPI 120 V V TG+ L + + ++ I+DG RP+ Sbjct: 82 VGDP-VLRTGKPLSVELGPGLMETIYDGIQRPL 113 >3VR3-A nrPDB Length = 600 Score = 295 bits (754), Expect = 4e-80, Method: Composition-based stats. Identities = 87/344 (25%), Positives = 150/344 (43%), Gaps = 31/344 (9%) Query: 140 NPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKD 199 ++ P+ + TG IDT + +G + G + QI + + + Sbjct: 205 PIKQKLNPDVPMITGQRVIDTFFPVTKGGAAAVPGPFGAGKTVVQHQIAKWSDVDL---- 260 Query: 200 VHDGHEENFSIVFAAMGVNLETARFFKQDFEE-------NGSLERTSLFLNLANDPTIER 252 +V+ G +F E +ERT L N +N P R Sbjct: 261 ----------VVYVGCGERGNEMTDVVNEFPELIDPNTGESLMERTVLIANTSNMPVAAR 310 Query: 253 IITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDL 312 + +T AEY V + S +A+ALRE+S EE+PG GYP Y+ + L Sbjct: 311 EASIYTGITIAEYFRDM-GYDVAIMADSTSRWAEALREMSGRLEEMPGDEGYPAYLGSRL 369 Query: 313 STIYERAGRV-----EGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNK 367 + YER+GRV + R GSIT I ++ DI+ P+ T + + +D L K Sbjct: 370 AEYYERSGRVIALGSDQREGSITAISAVSPSGGDISEPVTQNTLRVVKVFWGLDSSLAQK 429 Query: 368 GIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAV---VGEEA 424 +P IN + S S L + +G M + D S+ + I ++ + + VG ++ Sbjct: 430 RHFPSINWIQSYS-LYSTEVGRYMDQILQQDWSDMVTEGMRILQEEEQLNEIVRLVGIDS 488 Query: 425 LSIEDKLSLEFLEKFEKTFITQGAYEDRTVFESLDQAWSLLRIY 468 LS D+L+LE + + ++ Q A++D F S ++ +++L++ Sbjct: 489 LSDNDRLTLEVAKSIREDYLQQNAFDDVDTFTSREKQFNMLKVI 532 Score = 93.3 bits (230), Expect = 2e-19, Method: Composition-based stats. Identities = 34/114 (29%), Positives = 60/114 (52%), Gaps = 4/114 (3%) Query: 19 GFNVKPRLNYNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQ 78 G + + + V+GPLV+ E + I ++ L G+++E+R D A +Q Sbjct: 1 GSSGSSGMQIGKIIKVSGPLVMAENMS---EASIQDMCLVGDLGVIGEIIEMRQDVASIQ 57 Query: 79 VFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYL 132 V+E TSGI + V TGE+L + + ++ ++FDG RP+D +V ++L Sbjct: 58 VYEETSGIGPGEP-VRSTGEALSVELGPGIISQMFDGIQRPLDTFMEVTQSNFL 110 >5YBH-A nrPDB Length = 368 Score = 295 bits (754), Expect = 4e-80, Method: Composition-based stats. Identities = 77/372 (20%), Positives = 149/372 (40%), Gaps = 23/372 (6%) Query: 97 GESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAED--YLDINGSPINPYARIYPEEMISTG 154 G + V +LG + + G D + Y ++ +P R E+ TG Sbjct: 18 GSHMHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTG 77 Query: 155 VSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAA 214 + ID++ + GQ++ IF+++G + + +G V Sbjct: 78 IKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIY--------------VIGL 123 Query: 215 MGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHV 274 +G + + R L ++ +++R +A AE+ + + V Sbjct: 124 IGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHK-V 182 Query: 275 LTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPI 334 + ++ YA ALR+V+ A E P RRGYP ++ L + ER G+++ GSIT Sbjct: 183 ALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKA-GGSITAFYT 241 Query: 335 LTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRK 394 + + +DD P+ + I +G I++ R L KG +P I+ L S+SR+ + E Sbjct: 242 VLLEDDDFADPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHR-- 299 Query: 395 DHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQGAYEDRTV 454 +L ++ + E S +DK+ + ++F+ Q T Sbjct: 300 IMAAAFRELLSEIEELRTIIDFGEYKPGENAS-QDKIYNKI--SVVESFLKQDYRLGFTY 356 Query: 455 FESLDQAWSLLR 466 ++++ +R Sbjct: 357 EQTMELIGETIR 368 >3L0O-A nrPDB Length = 427 Score = 99.8 bits (247), Expect = 2e-21, Method: Composition-based stats. Identities = 48/324 (14%), Positives = 104/324 (32%), Gaps = 28/324 (8%) Query: 118 RPIDNGPKVFAEDYLDINGSPINPYARIYPEE--MISTGVSAIDTMNSIARGQKIPIFSA 175 I+ P D ++ + + + E ID I +GQ+ I + Sbjct: 124 EAINYRPVEAVNDRVNFDNLTPDYPRERFILETDPKIYSTRLIDLFAPIGKGQRGMIVAP 183 Query: 176 SGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSL 235 I +I + + + + E ++ Sbjct: 184 PKAGKTTILKEIANGIA----------ENHPDTIRIILLIDERPEEVTDIRES------- 226 Query: 236 ERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAR 295 + + P +++ L L A+ L + V+ +L ++ A V Sbjct: 227 TNAIVIAAPFDMPPDKQVKVAELTLEMAKRLV-EFNYDVVILLDSLTRLARVYNIVVPPS 285 Query: 296 EEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITE 355 ++ P +Y + A R GS+T I + + T Sbjct: 286 GKLLTGGVDPAALYK--PKRFFGAARNTREGGSLTIIATALVETGSKMDEVIFEEFKGTG 343 Query: 356 G-QIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAA 414 ++ + RQL NK I+P IN+L S +R + + E +K L + + Sbjct: 344 NMELVLSRQLANKRIFPAINLLLSGTRREELLLDEETLKKVW-----LLRRMLSAMTEEE 398 Query: 415 AMKAVVGEEALSIEDKLSLEFLEK 438 + ++ + + + ++ L+ ++K Sbjct: 399 GLTLILNKLSETSSNEEFLKLIDK 422 >3ICE-A nrPDB Length = 422 Score = 92.1 bits (227), Expect = 5e-19, Method: Composition-based stats. Identities = 42/311 (13%), Positives = 99/311 (31%), Gaps = 30/311 (9%) Query: 95 FTGESLRIPVSEDMLGRIFDGS--------GRPIDNGPKVFAEDYLDINGSPINPYARIY 146 TG+++ + G + +P + K+ E+ ++ + R Sbjct: 95 RTGDTISGKIRPPKEGERYFALLKVNEVNFDKPENARNKILFENLTPLHANSRLRMERGN 154 Query: 147 PEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEE 206 T +D + I RGQ+ I + + I + P Sbjct: 155 GSTEDLTA-RVLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHP---------- 203 Query: 207 NFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYL 266 + ++ + E ++ + + + ++P + + + A+ L Sbjct: 204 DCVLMVLLIDERPEEVTEMQRLVKGE-------VVASTFDEPASRHVQVAEMVIEKAKRL 256 Query: 267 AYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRN 326 + ++ V+ +L ++ A A V A +V G + A R Sbjct: 257 V-EHKKDVIILLDSITRLARAYNTVVPASGKV-LTGGVDANALHRPKRFFG-AARNVEEG 313 Query: 327 GSITQIPILTMPNDDITHPIPDLTGYITEG-QIFVDRQLHNKGIYPPINVLPSLSRLMKS 385 GS+T I + + T ++ + R++ K ++P I+ S +R + Sbjct: 314 GSLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEEL 373 Query: 386 AIGEGMTRKDH 396 + +K Sbjct: 374 LTTQEELQKMW 384 >3BUJ-A nrPDB Length = 397 Score = 34.7 bits (78), Expect = 0.10, Method: Composition-based stats. Identities = 22/113 (19%), Positives = 38/113 (33%), Gaps = 2/113 (1%) Query: 212 FAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTE 271 G+ E F++ R + A P+ R + P +A T + L Sbjct: 65 LVGPGLLAEIVGDII-LFQDEPDHGRLRGVVGPAFSPSALRRLEPVIAGTVDDLLRPALA 123 Query: 272 RHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEG 324 R + ++ +++ Y ALR V G G D+ +R E Sbjct: 124 RGAMDVVDELA-YPLALRAVLGLLGLPAADWGAVGRWSRDVGRTLDRGASAED 175 >6HA8-V nrPDB Length = 548 Score = 34.4 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 18/121 (14%), Positives = 38/121 (31%), Gaps = 7/121 (5%) Query: 162 NSIARGQKIPIFSASGLPHNEIA-----AQICRQAGLVRPTKDVHDGHEENFSIVFAAMG 216 +I G+K+ I +G + + + V P+ ++ +E F + Sbjct: 318 FTIQHGEKVAIIGPNGSGKTTLLNIILGQETAEGSVWVSPSANIGYLTQEVFDLPLEQTP 377 Query: 217 VNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLT 276 L FK + +P + R+ + Y+ E+ VL Sbjct: 378 EELFENETFKARGHVQNLMRHLGFTAAQWTEPIKHMSMGERVKIKLMAYIL--EEKDVLI 435 Query: 277 I 277 + Sbjct: 436 L 436 >5ZXD-A nrPDB Length = 546 Score = 33.2 bits (74), Expect = 0.26, Method: Composition-based stats. Identities = 18/100 (18%), Positives = 34/100 (34%), Gaps = 3/100 (3%) Query: 158 IDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGV 217 ++ I G++ + +G + I +A + P DV +E + A+ Sbjct: 21 VNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQEVVADETPAVQA 80 Query: 218 NLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPR 257 L + EE L+ L +D ER+ Sbjct: 81 VLRADTKRLKLLEEERRLQGQ---LEQGDDTAAERLEKVY 117 >5VFU-A nrPDB Length = 361 Score = 33.2 bits (74), Expect = 0.26, Method: Composition-based stats. Identities = 22/171 (12%), Positives = 47/171 (27%), Gaps = 22/171 (12%) Query: 84 SGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYA 143 G+ V V+ + IP+ + + + ++ P V Y D+ G Sbjct: 64 EGMRVG---VDRNKYQIHIPLPPKIDPTV---TMMQVEEKPDV---TYSDVGGCKEQIEK 114 Query: 144 -RIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHD 202 R E + ++ +G + +F G A + + Sbjct: 115 LREVVETPLLHPERFVNLGIEPPKG--VLLFGPPGTGKTLCARAVANRTD-----ACFIR 167 Query: 203 GHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERI 253 + +G R FE + + +F + + R Sbjct: 168 VIGSELVQKY--VGEGARMVREL---FEMARTKKACLIFFDEIDAIGGARF 213 >5YJJ-A nrPDB Length = 713 Score = 33.2 bits (74), Expect = 0.27, Method: Composition-based stats. Identities = 39/251 (15%), Positives = 85/251 (33%), Gaps = 40/251 (15%) Query: 280 DMSSYADALREVSAAREEVPG----RRGYPGYMYTDLSTIYERAGRVEGRNG---SITQI 332 D E A ++PG R G PG T + + +R R G + + Sbjct: 67 DFFPLTVNYEEKMYAAGKIPGGFKKREGRPGDEATLTARLIDRPIRPLFPKGYRHDVQIM 126 Query: 333 PILTMPNDDITHPIPDLTGYITEGQIFVD-RQLHNKGIYPPINVL-PSLSRLMKSAIGEG 390 I+ + D + + + G + + + +G +NV ++ ++ + Sbjct: 127 NIVLSADPDCSPEMAAMIGS----SMALSVSDIPFQGPIAGVNVGYIDGKYVINPSVADK 182 Query: 391 MTRKD------HGDVSNQLYAKYAIGKDAAAMKAV-VGEEALSIEDKLSLEFLEKFEKTF 443 + H D N + A + ++ ++A+ G E + E ++ + Sbjct: 183 EISRLDLEVAGHKDAVNMVEAGASEITESEMLEAIFFGHEEIKRLVAFQQEIIDHIQP-- 240 Query: 444 ITQGAYEDRTVFESLDQAWSLLRIYPKEMLNRISPKILDEFYDRARDDADE--------- 494 I Q F +++ L+ ++ + F + RD+ + Sbjct: 241 IKQE-------FVPVERDEDLVEKVKSLTEDKGLKDTVLTFDKQQRDENLDALKEEVVGH 293 Query: 495 --DEEDPDTRS 503 DEEDP+ + Sbjct: 294 FLDEEDPENET 304 >5LXZ-B nrPDB Length = 604 Score = 33.2 bits (74), Expect = 0.28, Method: Composition-based stats. Identities = 25/147 (17%), Positives = 48/147 (32%), Gaps = 9/147 (6%) Query: 65 GQVLEIRG-DRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDML----GRIFDGSGRP 119 G++L + G D V D K +T + + P + G+IF Sbjct: 257 GKILSVSGLDDIGQLVPGKNEVYDPKTKAWTYTDKVRQFPTYPALFLMQNGKIFYSGANA 316 Query: 120 IDNGPKV-FAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGL 178 V D+ + + M+ T A + A+ +K + G+ Sbjct: 317 GYGPDDVGRTPGVWDVETNKFTKVPGMSDANMLET---ANTVLLPPAQDEKYMVIGGGGV 373 Query: 179 PHNEIAAQICRQAGLVRPTKDVHDGHE 205 ++++++ R A L DG Sbjct: 374 GESKLSSEKTRIADLKADDPKFVDGPS 400 >6DUE-A nrPDB Length = 787 Score = 33.2 bits (74), Expect = 0.29, Method: Composition-based stats. Identities = 11/42 (26%), Positives = 19/42 (45%) Query: 149 EMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQ 190 + T A+D ++++ + Q I + SG E QI R Sbjct: 168 HVFYTARRALDNLHAVNKSQTIIVSGESGAGKTEATKQIMRY 209 >6OME-A nrPDB Length = 508 Score = 32.8 bits (73), Expect = 0.35, Method: Composition-based stats. Identities = 22/149 (14%), Positives = 46/149 (30%), Gaps = 16/149 (10%) Query: 188 CRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETA--RFFKQDFEENGSLERTSLFLNLA 245 G++ T++ V+ M + ++ + N Sbjct: 316 INVTGIIPATENAIGSAAYKMGDVYVGMTGLSVEIGSTDAEGRLILADAISYALKYCNPT 375 Query: 246 ---NDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRR 302 + T+ + L + A + A + D+ A+A E A +P Sbjct: 376 RIIDFATLTGAMVVSLGESVAGFFANND-----VLARDL---AEASSETGEALWRMPLVE 427 Query: 303 GYPGYMYTDLSTIYERAGRVEGRNGSITQ 331 Y +++D++ + R GSIT Sbjct: 428 KYDQALHSDIADMK---NIGSNRAGSITA 453 >3HR8-A nrPDB Length = 356 Score = 32.8 bits (73), Expect = 0.35, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 37/112 (33%), Gaps = 16/112 (14%) Query: 144 RIYPEEMISTGVSAIDTMNSIA---RGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDV 200 ++ P E+I TG AID + RG+ + IF +A +A + Sbjct: 35 QVQPVEVIPTGSLAIDIATGVGGYPRGRIVEIFGQESSGKTTLALHAIAEAQKMGGVAAF 94 Query: 201 HDGHEENFSIVFA----------AMGVN--LETARFFKQDFEENGSLERTSL 240 D E V+A + E A + +G ++ + Sbjct: 95 ID-AEHALDPVYAKNLGVDLKSLLISQPDHGEQALEIVDELVRSGVVDLIVV 145 >5XEX-A nrPDB Length = 559 Score = 32.8 bits (73), Expect = 0.37, Method: Composition-based stats. Identities = 42/244 (17%), Positives = 84/244 (34%), Gaps = 32/244 (13%) Query: 280 DMSSYADALREVSAAREEVPG----RRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPIL 335 D E A ++PG R G PG T + + +R R G + I+ Sbjct: 55 DFFPLTVNYEEKMYAAGKIPGGFKKREGRPGDDATLTARLIDRPIRPLFPKGYKHDVQIM 114 Query: 336 TMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVL-PSLSRLMKSAIGEGMTRK 394 M P + I + +G +NV ++ + E + Sbjct: 115 NMVLSADPDCSPQMAAMIGSSMALSVSDIPFQGPIAGVNVGYIDGKYIINPTVEEKEVSR 174 Query: 395 D------HGDVSNQLYAKYAIGKDAAAMKAV-VGEEALS---IEDKLSLEFLEKFEKTFI 444 H D N + A + + ++A+ G E + + ++ ++ ++ FI Sbjct: 175 LDLEVAGHKDAVNMVEAGASEITEQEMLEAIFFGHEEIQRLVDFQQQIVDHIQPVKQEFI 234 Query: 445 ---TQGAYEDRTVFESLDQAW-SLLRIYPKEM----LNRISPKILDEFYDRARDDADEDE 496 A +R + ++ + + K+ L+ + +I++EF DE Sbjct: 235 PAERDEALVERVKSLTEEKGLKETVLTFDKQQRDENLDNLKEEIVNEFI---------DE 285 Query: 497 EDPD 500 EDP+ Sbjct: 286 EDPE 289 >1XZP-A nrPDB Length = 482 Score = 32.8 bits (73), Expect = 0.41, Method: Composition-based stats. Identities = 30/210 (14%), Positives = 66/210 (31%), Gaps = 23/210 (10%) Query: 127 FAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQ 186 + ++ G + R +E ++ + D + RG ++ I + + + + Sbjct: 205 YPDEIETNTGEVVTRLER--IKEKLTEELKKADAGILLNRGLRMVIVGKPNVGKSTLLNR 262 Query: 187 ICRQAGLVRPTKDVHDGHEENFSIVFAAM--------GVNLETARFFKQDFEENGSLER- 237 + + + + IV + GV ET + +L+ Sbjct: 263 LLNEDRAIVTDIPGTTRDVISEEIVIRGILFRIVDTAGVRSET-NDLVERLGIERTLQEI 321 Query: 238 ----TSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALRE--- 290 LF+ A+ P E + YL + V+ + + + Sbjct: 322 EKADIVLFVLDASSPLDEEDRKILERIKNKRYLVVINKVDVVEKINEEEIKNKLGTDRHM 381 Query: 291 --VSAAREEVPGRRGYPGYMYTDLSTIYER 318 +SA + E G +Y + I+ER Sbjct: 382 VKISALKGE--GLEKLEESIYRETQEIFER 409 >6EPC-H nrPDB Length = 433 Score = 32.4 bits (72), Expect = 0.46, Method: Composition-based stats. Identities = 22/171 (12%), Positives = 49/171 (28%), Gaps = 22/171 (12%) Query: 84 SGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYA 143 G+ V V+ + IP+ + + + ++ P V Y D+ G Sbjct: 136 EGMRVG---VDRNKYQIHIPLPPKIDPTV---TMMQVEEKPDV---TYSDVGGCKEQIEK 186 Query: 144 -RIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHD 202 R E + ++ +G + +F G A + + + Sbjct: 187 LREVVETPLLHPERFVNLGIEPPKG--VLLFGPPGTGKTLCARAVANRTDACFIPVIGSE 244 Query: 203 GHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERI 253 ++ +G R FE + + +F + + R Sbjct: 245 LVQKY-------VGEGARMVREL---FEMARTKKACLIFFDEIDAIGGARF 285 >3D8B-A nrPDB Length = 357 Score = 32.4 bits (72), Expect = 0.50, Method: Composition-based stats. Identities = 24/152 (15%), Positives = 45/152 (29%), Gaps = 36/152 (23%) Query: 81 EGTSGIDVKKTTVEFTGESLRIP-----VSEDMLGRIFDGSGRPIDNGPKVFAEDYLDIN 135 E G+ K T + + + M+ I + +D+GP V ED + Sbjct: 34 EQNGGMQCKPYGAGPTEPAHPVDERLKNLEPKMIELIMNEI---MDHGPPVNWEDIAGVE 90 Query: 136 GSPINPYARIYPEEMIS---------TGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQ 186 +A+ +E++ TG+ + I +F G I Sbjct: 91 ------FAKATIKEIVVWPMLRPDIFTGLR--------GPPKGILLFGPPGTGKTLIGKC 136 Query: 187 ICRQAGLVRPTKDVHDGHEENFSIVFAAMGVN 218 I Q+G + + + G Sbjct: 137 IASQSG-----ATFFSISASSLTSKWVGEGEK 163 >4D81-A nrPDB Length = 283 Score = 32.1 bits (71), Expect = 0.56, Method: Composition-based stats. Identities = 32/258 (12%), Positives = 78/258 (30%), Gaps = 27/258 (10%) Query: 161 MNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLE 220 + + + I ++ G IAA + + D + G + Sbjct: 39 LFPLGWPRGILLYGPPGCGKTMIAAAVANELDSEFIHVDAASIMSKWL-------GEAEK 91 Query: 221 TARFFKQDFEENGSLER--TSLFLNLANDPTIERIITPRLALTTAEYLAYQT---ERHVL 275 + E E +F++ + ++ + E E L Sbjct: 92 NVAKIFKTARELSKKENKPAIIFIDELDA-----LLASYTSEVGGEARVRNQFLKEMDGL 146 Query: 276 TILTDMSS-YADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPI 334 ++S Y +E RR + +Y L R ++ + + P Sbjct: 147 ADKNEISKVYVIGATNKPWRLDEPFLRR-FQKRIYITLPDKAHRLELLKHYSSKVKLDPN 205 Query: 335 LTMPN-DDITH-PIPDLTGYITE-GQIFVDRQLHNKGIY-P-PINVLP--SLSRLMKSAI 387 + + ++T I + + V +++ K + P IN+ + ++ K ++ Sbjct: 206 VNLEELAELTDGYTASDIRDIVQSAHMRVVKEMFEKNLQEPRAINMDDFREVLKVRKPSV 265 Query: 388 GEGMTRKDHGDVSNQLYA 405 + M + + + A Sbjct: 266 NQDMLKA-YAAWHEKFKA 282 >4LGM-A nrPDB Length = 295 Score = 32.1 bits (71), Expect = 0.59, Method: Composition-based stats. Identities = 10/59 (16%), Positives = 18/59 (30%), Gaps = 7/59 (11%) Query: 161 MNSIARGQKIPIFSASGLPHNEIAAQICR-------QAGLVRPTKDVHDGHEENFSIVF 212 + + + I ++ G IAA + Q E+N + VF Sbjct: 51 LFPLGWPRGILLYGPPGCGKTMIAAAVANEIDSIFMQLDAASVMSKWLGEAEKNVANVF 109 >2FEZ-A nrPDB Length = 388 Score = 32.1 bits (71), Expect = 0.63, Method: Composition-based stats. Identities = 21/129 (16%), Positives = 32/129 (24%), Gaps = 11/129 (8%) Query: 171 PIFSASGLPH--NEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQD 228 SG P +A + + V + EE A ++ Sbjct: 25 GTPVPSGTPKQRAVLAMLVINRNRPVGVDALITALWEEWPPS--GARASIHSYVSNLRKL 82 Query: 229 FEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADAL 288 G R L P R+ P + E+ + A Sbjct: 83 LGGAGIDPRVVLAAA----PPGYRLSIPDNTCDLG---RFVAEKTAGVHAAAAGRFEQAS 135 Query: 289 REVSAAREE 297 R +SAA E Sbjct: 136 RHLSAALRE 144 >6QUZ-B nrPDB Length = 599 Score = 31.7 bits (70), Expect = 0.87, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 30/76 (39%), Gaps = 2/76 (2%) Query: 159 DTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTK--DVHDGHEENFSIVFAAMG 216 D I GQK+ + +G I + R + R D D + S + +++G Sbjct: 373 DITFHIKPGQKVALVGPTGSGKTTIVNLLMRFYDVDRGQILVDGIDIRKIKRSSLRSSIG 432 Query: 217 VNLETARFFKQDFEEN 232 + L+ F +EN Sbjct: 433 IVLQDTILFSTTVKEN 448 >1JI0-A nrPDB Length = 240 Score = 31.7 bits (70), Expect = 0.87, Method: Composition-based stats. Identities = 11/77 (14%), Positives = 23/77 (29%), Gaps = 8/77 (10%) Query: 155 VSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICR--QAGLVRPTKDVHDGHEENFSIV- 211 + ID RGQ + + A+G + I +A + + D + ++ Sbjct: 22 IKGIDLKVP--RGQIVTLIGANGAGKTTTLSAIAGLVRAQKGKIIFNGQDITNKPAHVIN 79 Query: 212 ---FAAMGVNLETARFF 225 A + Sbjct: 80 RMGIALVPEGRRIFPEL 96 >4Q7L-A nrPDB Length = 256 Score = 31.3 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 30/76 (39%), Gaps = 2/76 (2%) Query: 159 DTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTK--DVHDGHEENFSIVFAAMG 216 D I GQK+ + +G I + R + R D D + S + +++G Sbjct: 23 DITFHIKPGQKVALVGPTGSGKTTIVNLLMRFYDVDRGQILVDGIDIRKIKRSSLRSSIG 82 Query: 217 VNLETARFFKQDFEEN 232 + L+ F +EN Sbjct: 83 IVLQDTILFSTTVKEN 98 >6IC4-I nrPDB Length = 233 Score = 30.9 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 24/76 (31%), Gaps = 2/76 (2%) Query: 154 GVSAI--DTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIV 211 G I + +I RGQ I SG + I Q + + S Sbjct: 12 GERVIYDNISLNIRRGQITAIMGPSGTGKTTLLRLIGGQLVPDQGEVLLDGKDIAQMSRQ 71 Query: 212 FAAMGVNLETARFFKQ 227 A MG+ ++ F Sbjct: 72 RARMGMLFQSGALFTD 87 >5VHO-A nrPDB Length = 267 Score = 30.9 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 12/110 (10%), Positives = 27/110 (24%), Gaps = 12/110 (10%) Query: 144 RIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDG 203 R E + ++ +G + +F G A + + Sbjct: 31 REVVETPLLHPERFVNLGIEPPKG--VLLFGPPGTGKTLCARAVANRTD-----ACFIRV 83 Query: 204 HEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERI 253 + +G R FE + + +F + + R Sbjct: 84 IGSELVQKY--VGEGARMVREL---FEMARTKKACLIFFDEIDAIGGARF 128 >4H51-A nrPDB Length = 420 Score = 30.5 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 27/68 (39%), Gaps = 5/68 (7%) Query: 73 DRAIVQVFEGTSGID--VKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAED 130 D A+ ++ T ++ V T+ TG + + +L R+FD PI + Sbjct: 94 DEAVKIIYGNTVELENLVAVQTLSGTGA---VSLGAKLLTRVFDAETTPIYLSDPTWPNH 150 Query: 131 YLDINGSP 138 Y + + Sbjct: 151 YGVVKAAG 158 >4RY2-A nrPDB Length = 730 Score = 30.5 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 8/55 (14%), Positives = 19/55 (34%), Gaps = 2/55 (3%) Query: 155 VSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFS 209 + I+ +G+ + I SG +A + + ++ +N S Sbjct: 505 LKNINLTIP--KGKTVAIVGESGSGKTTLAKLLMNFYSPEKGDILINGHSIKNIS 557 >3PXI-A nrPDB Length = 758 Score = 30.1 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 19/111 (17%), Positives = 38/111 (34%), Gaps = 10/111 (9%) Query: 172 IFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEE 231 + G+ IA + +Q + + D + G + + + + Sbjct: 206 LIGEPGVGKTAIAEGLAQQIINNEVPEILRDKRVMTLDMGTKYRGEFEDRLKKVMDEIRQ 265 Query: 232 NGSLERTSLFLNLAND------PTIER-IITPRLALTTAEYLAYQTERHVL 275 G++ LF++ A D P++ R + A T EY Y + L Sbjct: 266 AGNI---ILFIDAAIDASNILKPSLARGELQCIGATTLDEYRKYIEKDAAL 313 >4Z8X-A nrPDB Length = 497 Score = 30.1 bits (66), Expect = 2.7, Method: Composition-based stats. Identities = 12/97 (12%), Positives = 31/97 (31%), Gaps = 14/97 (14%) Query: 167 GQK----IPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETA 222 G + + ++ G+ +A I +A + +F +F +G Sbjct: 47 GGRPPKGVLLYGEPGVGKTLLAKAIAGEAHVP-----FISVSGSDFVEMFVGVG--AARV 99 Query: 223 RFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLA 259 R + +++ +F++ + R P Sbjct: 100 RDLFETAKKHAP---CMIFIDEIDAVGRARGAIPVGG 133 >3PXG-A nrPDB Length = 468 Score = 29.7 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 19/111 (17%), Positives = 38/111 (34%), Gaps = 10/111 (9%) Query: 172 IFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEE 231 + G+ IA + +Q + + D + G + + + + Sbjct: 206 LIGEPGVGKTAIAEGLAQQIINNEVPEILRDKRVMTLDMGTKYRGEFEDRLKKVMDEIRQ 265 Query: 232 NGSLERTSLFLNLAND------PTIER-IITPRLALTTAEYLAYQTERHVL 275 G++ LF++ A D P++ R + A T EY Y + L Sbjct: 266 AGNI---ILFIDAAIDASNILKPSLARGELQCIGATTLDEYRKYIEKDAAL 313 >4FIN-A nrPDB Length = 555 Score = 29.7 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 13/32 (40%) Query: 159 DTMNSIARGQKIPIFSASGLPHNEIAAQICRQ 190 D SI +G + I +G + + I Q Sbjct: 341 DLSFSIPKGAIVGIIGPNGAGKSTLFRMISGQ 372 >5X41-A nrPDB Length = 280 Score = 29.7 bits (65), Expect = 3.1, Method: Composition-based stats. Identities = 20/121 (16%), Positives = 45/121 (37%), Gaps = 6/121 (4%) Query: 154 GVSAIDTM-NSIARGQKIPIFSASGLPHNEIA----AQICRQAGLVRPTKDVHDGHEENF 208 GV A+D + ++ +G+ + I +G + + + Q+G V ++ Sbjct: 17 GVKALDDLSLAVPKGESLAILGPNGAGKSTLLLHLNGTLRPQSGRVLLGGTATGHSRKDL 76 Query: 209 SIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAY 268 + +G+ L+ A + L L L+ R+ AL+ ++ L Sbjct: 77 TGWRRRVGLVLQDADDQLFATTVFEDVSFGPLNLGLSEAEARARVEEALAALSISD-LRD 135 Query: 269 Q 269 + Sbjct: 136 R 136 >3A22-A nrPDB Length = 614 Score = 29.7 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 30/83 (36%), Gaps = 9/83 (10%) Query: 19 GFNVKPRLNYNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQ 78 GF + + ++G ++ +E G ++ +V+ + D +Q Sbjct: 246 GFTAAQNRTHMNLWAISGAPLLAGNDLTTMTSE------TAGILKNPEVIAVDQDSRGLQ 299 Query: 79 ---VFEGTSGIDVKKTTVEFTGE 98 V E T+G+ + TG Sbjct: 300 GVKVAEDTTGLQAYGKVLSGTGN 322 >5FM7-A nrPDB Length = 464 Score = 29.4 bits (64), Expect = 3.8, Method: Composition-based stats. Identities = 12/72 (16%), Positives = 23/72 (31%), Gaps = 11/72 (15%) Query: 165 ARGQKIPIFSASGLPHNEIAAQICRQAGLVRP----TKDVHDGHEENFSIVFA-----AM 215 RG + + G +A I ++ G P T E + V A+ Sbjct: 66 GRG--VLLAGGPGTGKTALALAISQELGTKIPFCPITGSEIYSTEVKKTEVLMENFRRAI 123 Query: 216 GVNLETARFFKQ 227 G+ + + + Sbjct: 124 GLRVRETKDVYE 135 >1XP8-A nrPDB Length = 366 Score = 29.0 bits (63), Expect = 4.9, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 30/77 (38%), Gaps = 5/77 (6%) Query: 149 EMISTGVSAIDTMNSIA---RGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHE 205 +++STG ++D + RG+ I+ +A I QA E Sbjct: 53 QVVSTGSLSLDLALGVGGIPRGRITEIYGPESGGKTTLALAIVAQAQKAG-GTCAFIDAE 111 Query: 206 ENFSIVFA-AMGVNLET 221 V+A A+GVN + Sbjct: 112 HALDPVYARALGVNTDE 128 >3NHB-A nrPDB Length = 306 Score = 28.6 bits (62), Expect = 6.1, Method: Composition-based stats. Identities = 7/51 (13%), Positives = 16/51 (31%) Query: 159 DTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFS 209 D ++ GQ + + SG + I + R + + + Sbjct: 72 DVSFTVMPGQTLALVGPSGAGKSTILRLLFRFYDISSGCIRIDGQDISQVT 122 >6BLB-A nrPDB Length = 355 Score = 28.2 bits (61), Expect = 8.2, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 17/41 (41%), Gaps = 5/41 (12%) Query: 165 ARGQKI-----PIFSASGLPHNEIAAQICRQAGLVRPTKDV 200 ARG++ IF GL +A I ++ G+ + Sbjct: 52 ARGRQEALDHTLIFGPPGLGKTTLANIIAQEMGVSIKSTSG 92 >4MRS-A nrPDB Length = 614 Score = 28.2 bits (61), Expect = 9.6, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 23/56 (41%), Gaps = 2/56 (3%) Query: 164 IARGQKIPIFSASGLPHNEIAAQICR--QAGLVRPTKDVHDGHEENFSIVFAAMGV 217 +A G ++ I SG + IA + R R D D + + AA+G+ Sbjct: 384 VAAGSRVAIVGPSGAGKSTIARLLFRFYDPWEGRILIDGQDIAHVTQTSLRAALGI 439 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.305 0.125 0.301 Lambda K H 0.267 0.0389 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,062,999 Number of Sequences: 36641 Number of extensions: 663663 Number of successful extensions: 2761 Number of sequences better than 10.0: 81 Number of HSP's better than 10.0 without gapping: 107 Number of HSP's successfully gapped in prelim test: 39 Number of HSP's that attempted gapping in prelim test: 2334 Number of HSP's gapped (non-prelim): 165 length of query: 517 length of database: 10,336,785 effective HSP length: 101 effective length of query: 416 effective length of database: 6,636,044 effective search space: 2760594304 effective search space used: 2760594304 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 61 (28.2 bits)