BLASTP 2.2.23 [Feb-03-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= P16118
         (471 letters)

Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 
           36,641 sequences; 10,336,785 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

1K6M-A nrPDB                                                          890   0.0  
2BIF-A nrPDB                                                          725   0.0  
2DWP-A nrPDB                                                          689   0.0  
4D4L-A nrPDB                                                          687   0.0  
5HTK-A nrPDB                                                          671   0.0  
5HR5-A nrPDB                                                          671   0.0  
1C7Z-A nrPDB                                                          391   e-109
4IJ6-A nrPDB                                                           62   4e-10
1E58-A nrPDB                                                           52   4e-07
4EO9-A nrPDB                                                           52   6e-07
3PGM-A nrPDB                                                           51   1e-06
1RII-A nrPDB                                                           50   2e-06
6NRU-A nrPDB                                                           50   2e-06
1FZT-A nrPDB                                                           49   4e-06
3KKK-A nrPDB                                                           47   2e-05
5PGM-D nrPDB                                                           46   3e-05
5VVE-A nrPDB                                                           44   2e-04
4ODI-A nrPDB                                                           41   0.001
4EMB-A nrPDB                                                           40   0.002
3GW8-A nrPDB                                                           39   0.005
3D8H-A nrPDB                                                           37   0.015
4PZA-A nrPDB                                                           37   0.016
6BBQ-A nrPDB                                                           37   0.017
2A5F-A nrPDB                                                           36   0.042
5L3R-A nrPDB                                                           35   0.054
3LVQ-E nrPDB                                                           35   0.060
5NZV-F nrPDB                                                           34   0.15 
4YLG-A nrPDB                                                           34   0.16 
5UF8-A nrPDB                                                           33   0.21 
2B6H-A nrPDB                                                           33   0.22 
3AQ4-A nrPDB                                                           33   0.28 
3DM5-A nrPDB                                                           33   0.31 
3O47-A nrPDB                                                           33   0.32 
5CIO-A nrPDB                                                           33   0.37 
6DFF-C nrPDB                                                           32   0.49 
5Y64-B nrPDB                                                           32   0.52 
1J2J-A nrPDB                                                           32   0.55 
6FAE-B nrPDB                                                           32   0.56 
4C5U-A nrPDB                                                           32   0.67 
1G7S-A nrPDB                                                           32   0.75 
1Z6X-A nrPDB                                                           31   0.96 
4UZU-A nrPDB                                                           31   1.3  
5YPZ-A nrPDB                                                           31   1.4  
3LRP-A nrPDB                                                           30   1.9  
1F1O-A nrPDB                                                           30   3.0  
3LC3-A nrPDB                                                           30   3.0  
1X7A-C nrPDB                                                           29   3.7  
2RHQ-B nrPDB                                                           29   4.3  
3W15-A nrPDB                                                           29   5.6  

>1K6M-A nrPDB
          Length = 432

 Score =  890 bits (2299), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 427/432 (98%), Positives = 431/432 (99%)

Query: 40  NSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNM 99
           NSPTMVIMVGLPARGKTYISTKLTRYLN+IGTPTKVFNLGQYRREAVSYKNYEFFLPDNM
Sbjct: 1   NSPTMVIMVGLPARGKTYISTKLTRYLNFIGTPTKVFNLGQYRREAVSYKNYEFFLPDNM 60

Query: 100 EALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIES 159
           EALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIES
Sbjct: 61  EALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIES 120

Query: 160 ICNDPGIIAENIRQVKLGSPDYIDCDREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIK 219
           ICNDPGIIAENIRQVKLGSPDYIDCDREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIK
Sbjct: 121 ICNDPGIIAENIRQVKLGSPDYIDCDREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIK 180

Query: 220 IFDVGTRYMVNRVQDHIQSRTVYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVR 279
           IFDVGTRYMVNRVQDHIQSRTVYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVR
Sbjct: 181 IFDVGTRYMVNRVQDHIQSRTVYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVR 240

Query: 280 GKQYAYALANFIQSQGISSLKVWTSHMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTY 339
           GKQYAYALANFIQSQGISSLKV+TS MKRTIQTAEALGVPYEQ+KALNEIDAGVCEEMTY
Sbjct: 241 GKQYAYALANFIQSQGISSLKVFTSRMKRTIQTAEALGVPYEQFKALNEIDAGVCEEMTY 300

Query: 340 EEIQEHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRC 399
           EEIQEHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRC
Sbjct: 301 EEIQEHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRC 360

Query: 400 LLAYFLDKSSDELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITRE 459
           LLAYFLDKSS+ELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITRE
Sbjct: 361 LLAYFLDKSSEELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITRE 420

Query: 460 PEEALDTVPAHY 471
           PEEALDTVPAHY
Sbjct: 421 PEEALDTVPAHY 432


>2BIF-A nrPDB
          Length = 469

 Score =  725 bits (1871), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 347/466 (74%), Positives = 399/466 (85%), Gaps = 5/466 (1%)

Query: 7   ELTQTRLQKIWIPHSSGSSRLQ-RRRGSSIPQFTNSPTMVIMVGLPARGKTYISTKLTRY 65
           ELTQ  L+KI++P+S+G   L   +RG  +   TN PT+++MVGLPARGKTYIS KLTRY
Sbjct: 6   ELTQNPLKKIFMPYSNGRPALHASQRGVCM---TNCPTLIVMVGLPARGKTYISKKLTRY 62

Query: 66  LNWIGTPTKVFNLGQYRREAV-SYKNYEFFLPDNMEALQIRKQCALAALKDVHNYLSHEE 124
           LN+IG PT+ FN+GQYRR+ V +YK++EFFLPDN E L+IRKQCALAAL DV  +LS E 
Sbjct: 63  LNFIGVPTREFNVGQYRRDMVKTYKSFEFFLPDNEEGLKIRKQCALAALNDVRKFLSEEG 122

Query: 125 GHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPDYIDC 184
           GHVAVFDATNTTRERR++I  F +++GYK FF+ESIC DP +IA NI QVKLGSPDY++ 
Sbjct: 123 GHVAVFDATNTTRERRAMIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYVNR 182

Query: 185 DREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIKIFDVGTRYMVNRVQDHIQSRTVYYL 244
           D ++  EDF++RIECYE +Y+ LDEE D  LSYIKI DVG  Y+VNRV DHIQSR VYYL
Sbjct: 183 DSDEATEDFMRRIECYENSYESLDEEQDRDLSYIKIMDVGQSYVVNRVADHIQSRIVYYL 242

Query: 245 MNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLKVWTS 304
           MNIHVTPRSIYLCR GESELN++GRIGGD GLS RG++++  LA FI  Q I  LKV+TS
Sbjct: 243 MNIHVTPRSIYLCRAGESELNLKGRIGGDPGLSPRGREFSKHLAQFISDQNIKDLKVFTS 302

Query: 305 HMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPK 364
            MKRTIQTAEAL VPYEQ+K LNEIDAGVCEEMTYEEIQ+HYP EFALRDQDKYRYRYPK
Sbjct: 303 QMKRTIQTAEALSVPYEQFKVLNEIDAGVCEEMTYEEIQDHYPLEFALRDQDKYRYRYPK 362

Query: 365 GESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLK 424
           GESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDK+++ELPYLKCPLHTVLK
Sbjct: 363 GESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEELPYLKCPLHTVLK 422

Query: 425 LTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAH 470
           LTPVAYGCKVESI+LNV AVNTHR++P+NVDI+R  EEAL TVPAH
Sbjct: 423 LTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPSEEALVTVPAH 468


>2DWP-A nrPDB
          Length = 520

 Score =  689 bits (1777), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 321/450 (71%), Positives = 385/450 (85%), Gaps = 6/450 (1%)

Query: 7   ELTQTRLQKIWIPHSSGSSRLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYISTKLTRYL 66
           ELTQ+R+QKIW+P     S L R  G   P+ TNSPT+++MVGLPARGKTYIS KLTRYL
Sbjct: 4   ELTQSRVQKIWVPVDHRPS-LPRSCG---PKLTNSPTVIVMVGLPARGKTYISKKLTRYL 59

Query: 67  NWIGTPTKVFNLGQYRREAVS-YKNYEFFLPDNMEALQIRKQCALAALKDVHNYLSHEEG 125
           NWIG PTKVFN+G+YRREAV  Y +Y FF PDN EA+++RKQCALAAL+DV +YL+ E G
Sbjct: 60  NWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGG 119

Query: 126 HVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPDYIDCD 185
            +AVFDATNTTRERR +IL FAKE+ +K FFIES+C+DP ++A NI +VK+ SPDY DC+
Sbjct: 120 QIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCN 179

Query: 186 REKVLEDFLKRIECYEVNYQPLD-EELDSHLSYIKIFDVGTRYMVNRVQDHIQSRTVYYL 244
             + ++DF+KRI CYE +YQPLD ++ D  LS IK+ DVG R++VNRVQDHIQSR VYYL
Sbjct: 180 SAEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYL 239

Query: 245 MNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLKVWTS 304
           MNIHV PR+IYLCRHGE+E N++GRIGGDSGLS RGK++A AL+ F++ Q +  L+VWTS
Sbjct: 240 MNIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTS 299

Query: 305 HMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPK 364
            +K TIQTAEAL +PYEQWKALNEIDAGVCEE+TYEEI++ YPEE+ALR+QDKY YRYP 
Sbjct: 300 QLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPT 359

Query: 365 GESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLK 424
           GESY+DLVQRLEPVIMELERQENVLVICHQAV+RCLLAYFLDKS++E+PYLKCPLHTVLK
Sbjct: 360 GESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLK 419

Query: 425 LTPVAYGCKVESIYLNVEAVNTHREKPENV 454
           LTPVAYGC+VESIYLNVE+V THRE+ E+ 
Sbjct: 420 LTPVAYGCRVESIYLNVESVCTHRERSEDA 449


>4D4L-A nrPDB
          Length = 449

 Score =  687 bits (1773), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 321/450 (71%), Positives = 385/450 (85%), Gaps = 6/450 (1%)

Query: 7   ELTQTRLQKIWIPHSSGSSRLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYISTKLTRYL 66
           ELTQ+R+QKIW+P     S L R  G   P+ TNSPT+++MVGLPARGKTYIS KLTRYL
Sbjct: 4   ELTQSRVQKIWVPVDHRPS-LPRSCG---PKLTNSPTVIVMVGLPARGKTYISKKLTRYL 59

Query: 67  NWIGTPTKVFNLGQYRREAVS-YKNYEFFLPDNMEALQIRKQCALAALKDVHNYLSHEEG 125
           NWIG PTKVFN+G+YRREAV  Y +Y FF PDN EA+++RKQCALAAL+DV +YL+ E G
Sbjct: 60  NWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGG 119

Query: 126 HVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPDYIDCD 185
            +AVFDATNTTRERR +IL FAKE+ +K FFIES+C+DP ++A NI +VK+ SPDY DC+
Sbjct: 120 QIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCN 179

Query: 186 REKVLEDFLKRIECYEVNYQPLD-EELDSHLSYIKIFDVGTRYMVNRVQDHIQSRTVYYL 244
             + ++DF+KRI CYE +YQPLD ++ D  LS IK+ DVG R++VNRVQDHIQSR VYYL
Sbjct: 180 SAEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYL 239

Query: 245 MNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLKVWTS 304
           MNIHV PR+IYLCRHGE+E N++GRIGGDSGLS RGK++A AL+ F++ Q +  L+VWTS
Sbjct: 240 MNIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTS 299

Query: 305 HMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPK 364
            +K TIQTAEAL +PYEQWKALNEIDAGVCEE+TYEEI++ YPEE+ALR+QDKY YRYP 
Sbjct: 300 QLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPT 359

Query: 365 GESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLK 424
           GESY+DLVQRLEPVIMELERQENVLVICHQAV+RCLLAYFLDKS++E+PYLKCPLHTVLK
Sbjct: 360 GESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLK 419

Query: 425 LTPVAYGCKVESIYLNVEAVNTHREKPENV 454
           LTPVAYGC+VESIYLNVE+V THRE+ E+ 
Sbjct: 420 LTPVAYGCRVESIYLNVESVCTHRERSEDA 449


>5HTK-A nrPDB
          Length = 505

 Score =  671 bits (1731), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 312/430 (72%), Positives = 369/430 (85%), Gaps = 2/430 (0%)

Query: 26  RLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREA 85
           R+  ++ S     TNSPT+++M+GLPARGKTY+S KLTRYLNWIG PTKVFNLG YRREA
Sbjct: 22  RMSEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREA 81

Query: 86  V-SYKNYEFFLPDNMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSLIL 144
           V SYK+Y+FF  DN EA++IRKQCAL AL+DV  YL+ E G +AVFDATNTTRERR +IL
Sbjct: 82  VKSYKSYDFFRHDNEEAMKIRKQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDMIL 141

Query: 145 QFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPDYIDCDREKVLEDFLKRIECYEVNY 204
            FA+++ +KVFF+ES+C+DP +IA NI +VK+ SPDY + +RE V+EDFLKRIECY+V Y
Sbjct: 142 NFAEQNSFKVFFVESVCDDPDVIAANILEVKVSSPDYPERNRENVMEDFLKRIECYKVTY 201

Query: 205 QPLD-EELDSHLSYIKIFDVGTRYMVNRVQDHIQSRTVYYLMNIHVTPRSIYLCRHGESE 263
           +PLD +  D  LS+IK+ +VG R++VNRVQD+IQS+ VYYLMNIHV PR+IYLCRHGESE
Sbjct: 202 RPLDPDNYDKDLSFIKVINVGQRFLVNRVQDYIQSKIVYYLMNIHVQPRTIYLCRHGESE 261

Query: 264 LNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQTAEALGVPYEQW 323
            N+ G+IGGDSGLSVRGKQ+A AL  F++ Q I+ LKVWTS +KRTIQTAE+LGVPYEQW
Sbjct: 262 FNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQTAESLGVPYEQW 321

Query: 324 KALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELE 383
           K LNEIDAGVCEEMTY EI++ YPEEFALRDQ+KY YRYP GESY+DLVQRLEPVIMELE
Sbjct: 322 KILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYPGGESYQDLVQRLEPVIMELE 381

Query: 384 RQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEA 443
           RQ NVLVI HQAVMRCLLAYFLDK +DELPYL+CPLHT+ KLTPVAYGCKVE+I LNVEA
Sbjct: 382 RQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYGCKVETIKLNVEA 441

Query: 444 VNTHREKPEN 453
           VNTHR+KP N
Sbjct: 442 VNTHRDKPTN 451


>5HR5-A nrPDB
          Length = 531

 Score =  671 bits (1730), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 313/435 (71%), Positives = 370/435 (85%), Gaps = 2/435 (0%)

Query: 21  SSGSSRLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQ 80
           +  S R+  ++ S     TNSPT+++M+GLPARGKTY+S KLTRYLNWIG PTKVFNLG 
Sbjct: 18  TKASLRISEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGV 77

Query: 81  YRREAV-SYKNYEFFLPDNMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRER 139
           YRR+AV SYK+Y+FF  DN EA++IRKQCAL ALKDV  YL+ E G +AVFDATNTTRER
Sbjct: 78  YRRQAVKSYKSYDFFRHDNEEAMKIRKQCALVALKDVKAYLTEESGQIAVFDATNTTRER 137

Query: 140 RSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPDYIDCDREKVLEDFLKRIEC 199
           R LIL FA+E+ +KVFF+ES+C+DP +IA NI +VK+ SPDY + +RE V++DFLKRIEC
Sbjct: 138 RDLILNFAEENSFKVFFVESVCDDPDVIAANILEVKVSSPDYPERNRENVMDDFLKRIEC 197

Query: 200 YEVNYQPLD-EELDSHLSYIKIFDVGTRYMVNRVQDHIQSRTVYYLMNIHVTPRSIYLCR 258
           Y+V YQPLD +  D  LS+IK+ +VG R++VN+VQD+IQS+ VYYLMNIHV PR+IYLCR
Sbjct: 198 YKVTYQPLDPDSHDKDLSFIKVINVGQRFLVNKVQDYIQSKIVYYLMNIHVHPRTIYLCR 257

Query: 259 HGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQTAEALGV 318
           HGESE N+ G+IGGDSGLSVRGKQ+A AL  F++ Q I+ LKVWTS +KRTIQTAE+LGV
Sbjct: 258 HGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEIADLKVWTSQLKRTIQTAESLGV 317

Query: 319 PYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPV 378
            YEQWK LNEIDAGVCEEMTY EIQE YP+EFALRD++KY YRYP GESY+DLVQRLEPV
Sbjct: 318 TYEQWKILNEIDAGVCEEMTYAEIQEQYPDEFALRDEEKYLYRYPGGESYQDLVQRLEPV 377

Query: 379 IMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTPVAYGCKVESIY 438
           IMELERQ NVLVI HQAVMRCLLAYFLDK +DELPYL+CPLHT+ KLTPVAYGCKVE+I 
Sbjct: 378 IMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYGCKVETIK 437

Query: 439 LNVEAVNTHREKPEN 453
           LNVEAVNTHR+KP N
Sbjct: 438 LNVEAVNTHRDKPTN 452


>1C7Z-A nrPDB
          Length = 191

 Score =  391 bits (1005), Expect = e-109,   Method: Compositional matrix adjust.
 Identities = 186/190 (97%), Positives = 189/190 (99%)

Query: 252 RSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQ 311
           RSIYLCRHGESELN+RGRIGGDSGLS RGKQYAYALANFI+SQGISSLKVWTSHMKRTIQ
Sbjct: 2   RSIYLCRHGESELNLRGRIGGDSGLSARGKQYAYALANFIRSQGISSLKVWTSHMKRTIQ 61

Query: 312 TAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDL 371
           TAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDL
Sbjct: 62  TAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDL 121

Query: 372 VQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTPVAYG 431
           VQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTPVAYG
Sbjct: 122 VQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTPVAYG 181

Query: 432 CKVESIYLNV 441
           C+VESIYLNV
Sbjct: 182 CRVESIYLNV 191


>4IJ6-A nrPDB
          Length = 211

 Score = 62.4 bits (150), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 49/173 (28%), Positives = 83/173 (47%), Gaps = 11/173 (6%)

Query: 254 IYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRT-- 309
           + L R  ESE N  GR  G  D  LS RGK+ A  LA  +  + +    +++S +KRT  
Sbjct: 4   LILVRAAESEWNPVGRYQGLLDPDLSERGKKQAKLLAQELSREHLDV--IYSSPLKRTYL 61

Query: 310 --IQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGES 367
             ++ AEA  +   +   + EID G+   M  EE+ E YPE+F    ++ ++  +  GES
Sbjct: 62  TALEIAEAKNLEVIKEDRIIEIDHGMWSGMLVEEVMEKYPEDFRRWVEEPHKVEFQGGES 121

Query: 368 YEDLVQRLEPVIMELERQ---ENVLVICHQAVMRCLLAYFLDKSSDELPYLKC 417
              +  R++  + E+ ++   + V+V+ H   MR +    L     +     C
Sbjct: 122 LASVYNRVKGFLEEVRKRHWNQTVVVVSHTVPMRAMYCALLGVDLSKFWSFGC 174


>1E58-A nrPDB
          Length = 249

 Score = 52.4 bits (124), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 54/204 (26%), Positives = 85/204 (41%), Gaps = 39/204 (19%)

Query: 254 IYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQ 311
           + L RHGES+ N   R  G  D  LS +G   A A    ++ +G S    +TS +KR I 
Sbjct: 5   LVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKLLKEEGYSFDFAYTSVLKRAIH 64

Query: 312 T-------AEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEE--------FAL---- 352
           T        +   +P E+   LNE   G  + +   E  E Y +E        FA+    
Sbjct: 65  TLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAETAEKYGDEQVKQWRRGFAVTPPE 124

Query: 353 --RDQDKY-----RY------RYPKGESYEDLVQRLEP-----VIMELERQENVLVICHQ 394
             +D ++Y     RY        P  ES    + R+ P     ++  ++  E V++  H 
Sbjct: 125 LTKDDERYPGHDPRYAKLSEKELPLTESLALTIDRVIPYWNETILPRMKSGERVIIAAHG 184

Query: 395 AVMRCLLAYFLDKSSDELPYLKCP 418
             +R L+ Y  + S +E+  L  P
Sbjct: 185 NSLRALVKYLDNMSEEEILELNIP 208


>4EO9-A nrPDB
          Length = 268

 Score = 51.6 bits (122), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 58/235 (24%), Positives = 91/235 (38%), Gaps = 47/235 (20%)

Query: 253 SIYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTI 310
           ++ L RHGES+ N R    G  D GL+ +G+  A      +    +    ++TS ++R I
Sbjct: 29  TLILLRHGESDWNARNLFTGWVDVGLTDKGRAEAVRSGELLAEHNLLPDVLYTSLLRRAI 88

Query: 311 -------QTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRY--- 360
                   TA+ L +P  +   LNE   G  + +     +  Y EE  +  +  Y     
Sbjct: 89  TTAHLALDTADWLWIPVRRSWRLNERHYGALQGLDKAVTKARYGEERFMAWRRSYDTPPP 148

Query: 361 --------------RY------PKGESYEDLVQRLEP-----VIMELERQENVLVICHQA 395
                         RY      P  E   D+V R  P     ++ +L     VL++ H  
Sbjct: 149 PIEKGSEFSQDADPRYTDIGGGPLTECLADVVTRFLPYFTDVIVPDLRTGRTVLIVAHGN 208

Query: 396 VMRCLLAYFLDKSSDELPYLKCPLHTVLK------LTPVAYGCKVESIYLNVEAV 444
            +R L+ +  + S DE+  L  P    L+      L PV  G      YL+ EA 
Sbjct: 209 SLRALVKHLDEMSDDEVVGLNVPTGIPLRYDLDADLRPVVPG----GTYLDPEAA 259


>3PGM-A nrPDB
          Length = 244

 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 51/208 (24%), Positives = 89/208 (42%), Gaps = 39/208 (18%)

Query: 254 IYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQ 311
           + L RHG+SE N +    G  D  LS +G+Q A      ++ +G++ L  +TS + R IQ
Sbjct: 3   LVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKEKGVNVLVDYTSKLSRAIQ 62

Query: 312 T-------AEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEE--------------- 349
           T       A+ L +P  +   LNE   G  +     +  + + EE               
Sbjct: 63  TANIALEKADRLWIPVNRSWRLNERHYGDLQGKDKAQTLKKFGEEKFNTYRRSFDVPPPP 122

Query: 350 ------FALRDQDKYRY----RYPKGESYEDLVQRLEP----VIMELERQENVLVICHQA 395
                 F+ +  ++Y+Y      P+ ES   ++ RL P    VI +L  + + ++  H  
Sbjct: 123 IDASSPFSQKGDERYKYVDPNVLPETESLALVIDRLLPYWQDVIAKLVGKTS-MIAAHGN 181

Query: 396 VMRCLLAYFLDKSSDELPYLKCPLHTVL 423
            +R L+ +    S  ++  L  P  T+L
Sbjct: 182 SLRGLVKHLEGISDADIAKLNIPPGTIL 209


>1RII-A nrPDB
          Length = 265

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 52/209 (24%), Positives = 82/209 (39%), Gaps = 37/209 (17%)

Query: 253 SIYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTI 310
           S+ L RHGES+ N      G  D GL+ +G+  A      I    +    ++TS ++R I
Sbjct: 6   SLVLLRHGESDWNALNLFTGWVDVGLTDKGQAEAVRSGELIAEHDLLPDVLYTSLLRRAI 65

Query: 311 QT-------AEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRY--- 360
            T       A+ L +P  +   LNE   G  + +   E +  Y EE  +  +  Y     
Sbjct: 66  TTAHLALDSADRLWIPVRRSWRLNERHYGALQGLDKAETKARYGEEQFMAWRRSYDTPPP 125

Query: 361 --------------RY------PKGESYEDLVQRLEP-----VIMELERQENVLVICHQA 395
                         RY      P  E   D+V R  P     ++ +L   + VL++ H  
Sbjct: 126 PIERGSQFSQDADPRYADIGGGPLTECLADVVARFLPYFTDVIVGDLRVGKTVLIVAHGN 185

Query: 396 VMRCLLAYFLDKSSDELPYLKCPLHTVLK 424
            +R L+ +    S DE+  L  P    L+
Sbjct: 186 SLRALVKHLDQMSDDEIVGLNIPTGIPLR 214


>6NRU-A nrPDB
          Length = 206

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 42/173 (24%), Positives = 82/173 (47%), Gaps = 13/173 (7%)

Query: 254 IYLCRHGESELNIRGRIGGDSG--LSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQ 311
           ++L RHGE++ N+ G   G +   L+ RG + A  L   +    +S   V  S ++R   
Sbjct: 6   LWLIRHGETQANVDGLYSGHAPTPLTARGIEQAQNLHTLLDD--VSFDLVLCSELERAQH 63

Query: 312 TAEAL----GVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYP-KGE 366
           TA  +     +P      LNE+  G  E   + ++ +   E ++    D +++  P  GE
Sbjct: 64  TARLVLSDRQLPVHIIPELNEMFFGDWEMRHHRDLMQEDAENYSAWCND-WQHAIPTNGE 122

Query: 367 SYEDLVQRLEPVIMEL---ERQENVLVICHQAVMRCLLAYFLDKSSDELPYLK 416
            ++   QR+E  I  L   +  +N+L++ HQ V+  L+A  +   ++ + + +
Sbjct: 123 GFQAFSQRVERFIARLSEYQHYQNILIVSHQGVLSLLIARLIGMPAESMWHFR 175


>1FZT-A nrPDB
          Length = 211

 Score = 49.3 bits (116), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 51/225 (22%), Positives = 92/225 (40%), Gaps = 37/225 (16%)

Query: 245 MNIHVTPRSIYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVW 302
           M     P  + L RHGESE N      G  D  LS  G + A      ++S+G      +
Sbjct: 1   MTTEAAPNLLVLTRHGESEWNKLNLFTGWKDPALSETGIKEAKLGGERLKSRGYKFDIAF 60

Query: 303 TSHMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRY 362
           TS ++R  +T + +         L E+     E +  E++ E Y  +    ++D  R ++
Sbjct: 61  TSALQRAQKTCQII---------LEEVGEPNLETIKSEKLNERYYGDLQGLNKDDARKKW 111

Query: 363 ----------------PKGESYEDLVQRLEP-----VIMELERQENVLVICHQAVMRCLL 401
                           P GES +D  +R+ P     ++  + + E VL+  H   +R L+
Sbjct: 112 GAEQVQIWRRSYDIAPPNGESLKDTAERVLPYYKSTIVPHILKGEKVLIAAHGNSLRALI 171

Query: 402 AYFLDKSSDELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEAVNT 446
                 + D++  +K  L T +   P+ Y    +  Y++ E ++ 
Sbjct: 172 MDLEGLTGDQI--VKRELATGV---PIVYHLDKDGKYVSKELIDN 211


>3KKK-A nrPDB
          Length = 258

 Score = 46.6 bits (109), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 51/209 (24%), Positives = 85/209 (40%), Gaps = 39/209 (18%)

Query: 249 VTPRSIYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHM 306
           +T  ++ L RHGES  N   +  G  D  LS +G++ A A   +++ +      V+TS +
Sbjct: 9   MTTYTLVLLRHGESTWNKENKFTGWTDVPLSEKGEEEAIAAGKYLKEKNFKFDVVYTSVL 68

Query: 307 KRTI-------QTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEE---------- 349
           KR I       +TA+ L VP  +   LNE   G  + +   E  + Y EE          
Sbjct: 69  KRAICTAWNVLKTADLLHVPVVKTWRLNERHCGSLQGLNKSETAKKYGEEQVKIWRRSYD 128

Query: 350 FALRDQDKYRYRYPK---------------GESYEDLVQRLEP-----VIMELERQENVL 389
                 DK   R+P                 E  +D V+R+ P     +  ++   + V+
Sbjct: 129 IPPPKLDKEDNRWPGHNVVYKNVPKDALPFTECLKDTVERVLPFWFDHIAPDILANKKVM 188

Query: 390 VICHQAVMRCLLAYFLDKSSDELPYLKCP 418
           V  H   +R L+ +  + S  ++  L  P
Sbjct: 189 VAAHGNSLRGLVKHLDNLSEADVLELNIP 217


>5PGM-D nrPDB
          Length = 246

 Score = 46.2 bits (108), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 47/204 (23%), Positives = 83/204 (40%), Gaps = 39/204 (19%)

Query: 254 IYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQ 311
           + L RHG+SE N +    G  D  LS +G+Q A      ++ + +    ++TS + R IQ
Sbjct: 3   LVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSRAIQ 62

Query: 312 T-------AEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEE--------------- 349
           T       A+ L +P  +   LNE   G  +     E  + + EE               
Sbjct: 63  TANIALEKADRLWIPVNRSWRLNERHYGDLQGKDKAETLKKFGEEKFNTYRRSFDVPPPP 122

Query: 350 ------FALRDQDKYRY----RYPKGESYEDLVQRLEP-----VIMELERQENVLVICHQ 394
                 F+ +  ++Y+Y      P+ ES   ++ RL P     +  +L   + V++  H 
Sbjct: 123 IDASSPFSQKGDERYKYVDPNVLPETESLALVIDRLLPYWQDVIAKDLLSGKTVMIAAHG 182

Query: 395 AVMRCLLAYFLDKSSDELPYLKCP 418
             +R L+ +    S  ++  L  P
Sbjct: 183 NSLRGLVKHLEGISDADIAKLNIP 206


>5VVE-A nrPDB
          Length = 258

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 53/205 (25%), Positives = 82/205 (40%), Gaps = 41/205 (20%)

Query: 254 IYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTI- 310
           + L RHGESE N   +  G  D GLS  G + A      +  +G      +TS +KR I 
Sbjct: 13  LVLIRHGESEWNKENKFTGWYDCGLSETGLKEAKEAGEILLKEGYEFDLCYTSFLKRAIK 72

Query: 311 ------QTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEF-------------A 351
                 +T +A+ +P  +   LNE   G  + +   +  E + EE              A
Sbjct: 73  TLWIALETMDAMYLPVVKHWRLNERHYGALQGLNKTQTAEKHGEEQVKIWRRSYDIPPPA 132

Query: 352 LRDQDKYRY-------------RYPKGESYEDLVQRLEP-----VIMELERQENVLVICH 393
           L   D+ RY               PK ES +  V R+ P     +   ++  + VL+  H
Sbjct: 133 LEVTDE-RYPGHERKYQGLTQEELPKTESLKLTVDRVLPYWNDVIAPSVKEGKRVLIAAH 191

Query: 394 QAVMRCLLAYFLDKSSDELPYLKCP 418
              +R L+ Y  + S +E+  L  P
Sbjct: 192 GNSLRALVKYLDNISEEEIVELNIP 216


>4ODI-A nrPDB
          Length = 281

 Score = 40.8 bits (94), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 55/211 (26%), Positives = 82/211 (38%), Gaps = 46/211 (21%)

Query: 243 YLMNIHVTPRSIYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLK 300
           +  N+     ++ L RHGES  N   R  G  D  LS  G+Q A   A  ++ +G     
Sbjct: 10  FFGNMAKAKYTLVLIRHGESTWNKENRFTGWTDVPLSPVGEQEAVEAAKALKEKGFEFDV 69

Query: 301 VWTSHMKRTIQT-------AEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEE---F 350
            +TS ++R + T        +   +P +    LNE   G  + +   E    + +E    
Sbjct: 70  AYTSVLQRAVVTCWTVLKGTDMCHIPVKSSWRLNERHYGALQGLNKAETAAKHGDEQVKI 129

Query: 351 ALRDQD-------KYRYRYPKG---------------ESYEDLVQR--------LEPVIM 380
             R  D       K   R+P                 E  +D V+R        + P IM
Sbjct: 130 WRRSYDIPPPPLEKSDKRWPGNDAVYKMVPNEALPLTECLKDTVERVLPFWFDHIAPSIM 189

Query: 381 ELERQENVLVICHQAVMRCLLAYFLDKSSDE 411
           E +R   VLV  H   +R L+ + LDK SDE
Sbjct: 190 EGKR---VLVAAHGNSLRGLVKH-LDKMSDE 216


>4EMB-A nrPDB
          Length = 274

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 51/205 (24%), Positives = 80/205 (39%), Gaps = 41/205 (20%)

Query: 254 IYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQ 311
           + L RHGESE N      G  D  LS +G   A      ++ +G S    ++S + R   
Sbjct: 30  LVLVRHGESEWNKENLFTGWTDVKLSDKGIDEAVEAGLLLKQEGYSFDIAFSSLLSRAND 89

Query: 312 TAE----ALGVPY----EQWKALNEIDAGVCEEMTYEEIQEHYPEEFAL----------- 352
           T       LG  Y    + W+ LNE   G  + +   E    Y E+  L           
Sbjct: 90  TLNIILRELGQSYISVKKTWR-LNERHYGALQGLNKSETAAKYGEDKVLIWRRSYDVPPM 148

Query: 353 ---RDQDKY-----RYRY------PKGESYEDLVQRLEP-----VIMELERQENVLVICH 393
                 D++     RY++      P  E  +D V R+ P     +  E+   + V+V  H
Sbjct: 149 SLDESDDRHPIKDPRYKHIPKRELPSTECLKDTVARVIPYWTDEIAKEVLEGKKVIVAAH 208

Query: 394 QAVMRCLLAYFLDKSSDELPYLKCP 418
              +R L+ YF + S +++  L  P
Sbjct: 209 GNSLRALVKYFDNLSEEDVLKLNIP 233


>3GW8-A nrPDB
          Length = 257

 Score = 38.9 bits (89), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 49/196 (25%), Positives = 74/196 (37%), Gaps = 40/196 (20%)

Query: 254 IYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQ 311
           + L RHGES  N   R  G  D  L+ +G + A      ++  G +    +TS +KR I+
Sbjct: 12  LVLIRHGESTWNKENRFTGWVDVDLTEQGNREARQAGQLLKEAGYTFDIAYTSVLKRAIR 71

Query: 312 T-------AEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKY------ 358
           T        + + VP      LNE   G    +   E    Y +E  L  +  Y      
Sbjct: 72  TLWHVQDQMDLMYVPVVHSWRLNERHYGALSGLNKAETAAKYGDEQVLVWRRSYDTPPPA 131

Query: 359 -------------------RYRYPKGESYEDLVQRLEPVIME-----LERQENVLVICHQ 394
                              R + P  E  +D V R+ P+  E     ++  + VL+  H 
Sbjct: 132 LEPGDERAPYADPRYAKVPREQLPLTECLKDTVARVLPLWNESIAPAVKAGKQVLIAAHG 191

Query: 395 AVMRCLLAYFLDKSSD 410
             +R L+ Y LD  SD
Sbjct: 192 NSLRALIKY-LDGISD 206


>3D8H-A nrPDB
          Length = 267

 Score = 37.4 bits (85), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 66/240 (27%), Positives = 93/240 (38%), Gaps = 51/240 (21%)

Query: 254 IYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQ 311
           + L RHGESE N   R  G  D  LS +G   A      +  +G     V+TS +KR I 
Sbjct: 23  LTLIRHGESEWNKENRFTGWTDVSLSEQGVSEAIEAGRMLLEKGFKFDVVYTSVLKRAIM 82

Query: 312 TA----EALG---VPYEQWKALNEIDAGVCEEMTYEEIQEHYPEE---FALRDQD----- 356
           T     + LG    P      LNE   G  + +   E    + E+      R  D     
Sbjct: 83  TTWTVLKELGNINCPIINHWRLNERHYGALQGLNKSETASKFGEDQVKIWRRSFDVPPPV 142

Query: 357 --KYRYRYP------KG---------ESYEDLVQRLEP-----VIMELERQENVLVICHQ 394
             K   R+P      KG         E  +D V+R++P     +   +   ++VLV  H 
Sbjct: 143 LEKSDPRWPGNELIYKGICPSCLPTTECLKDTVERVKPYFEDVIAPSIMSGKSVLVSAHG 202

Query: 395 AVMRCLLAYFLDKSSDE------LPYLKCP----LHTVLKLTPVAYGCKVESIYLNVEAV 444
             +R LL Y L+  + E      +P   CP    L   LK+T   Y    E +   +EAV
Sbjct: 203 NSLRALL-YLLEGMTPEQILEVNIP-TACPLVLELDDYLKVTKKYYLISEEELKAKMEAV 260


>4PZA-A nrPDB
          Length = 223

 Score = 37.0 bits (84), Expect = 0.016,   Method: Compositional matrix adjust.
 Identities = 38/142 (26%), Positives = 63/142 (44%), Gaps = 11/142 (7%)

Query: 252 RSIYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRT 309
           R + + RHG+++ N+  R+ G  D+ LS  G+  A A A  +  +    L + +S ++R 
Sbjct: 4   RRLVMLRHGQTDYNVGSRMQGQLDTELSELGRTQAVAAAEVLGKR--QPLLIVSSDLRRA 61

Query: 310 IQTA----EALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYP-EEFALRDQDKYRYRYPK 364
             TA    E  G+       L E   G  + +T+ +I    P    A R+   +      
Sbjct: 62  YDTAVKLGERTGLVVRVDTRLRETHLGDWQGLTHAQIDADAPGARLAWREDATWAPH--G 119

Query: 365 GESYEDLVQRLEPVIMELERQE 386
           GES  D+  R  P++ EL   E
Sbjct: 120 GESRVDVAARSRPLVAELVASE 141


>6BBQ-A nrPDB
          Length = 520

 Score = 37.0 bits (84), Expect = 0.017,   Method: Compositional matrix adjust.
 Identities = 25/73 (34%), Positives = 38/73 (52%), Gaps = 6/73 (8%)

Query: 26  RLQRRRGSSIPQ-FTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRRE 84
           R+  ++G  + + F N    ++M+GL A GKT I  KL    +    PT  FN+     E
Sbjct: 342 RIANKKGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNV-----E 396

Query: 85  AVSYKNYEFFLPD 97
            V+YKN +F + D
Sbjct: 397 TVTYKNVKFNVWD 409


>2A5F-A nrPDB
          Length = 175

 Score = 35.8 bits (81), Expect = 0.042,   Method: Compositional matrix adjust.
 Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 13/100 (13%)

Query: 38  FTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPD 97
           F N    ++M+GL A GKT I  KL    +    PT  FN+     E V+YKN +F + D
Sbjct: 9   FGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNV-----ETVTYKNVKFNVWD 63

Query: 98  NMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTR 137
                +IR            +Y +  +G + V D  +  R
Sbjct: 64  VGGQDKIRPLW--------RHYYTGTQGLIFVVDCADRDR 95


>5L3R-A nrPDB
          Length = 301

 Score = 35.4 bits (80), Expect = 0.054,   Method: Compositional matrix adjust.
 Identities = 44/179 (24%), Positives = 68/179 (37%), Gaps = 40/179 (22%)

Query: 37  QFTNS-PTMVIMVGLPARGKTYISTKLTRYLN---------------------------- 67
           QF  S PT++++ GL   GKT +  KL  YL                             
Sbjct: 100 QFAKSGPTVILLAGLQGVGKTTVCAKLACYLKKQGKSCMLIAGDVYRPAAIDQLVILGEQ 159

Query: 68  ------WIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALQIRKQCALAALKDVHNYLS 121
                   GT  K  ++ +   +     N +  + D    LQI K   +  LKDV  +L+
Sbjct: 160 VGVPVYTAGTDVKPADIAKQGLKEAKKNNVDVVIMDTAGRLQIDKGM-MDELKDVKKFLN 218

Query: 122 HEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDP-GIIAENIRQVKLGSP 179
             E  + V DA  T +E  +L+  F  E G     +  +  D  G  A ++++V  G P
Sbjct: 219 PTE-VLLVVDAM-TGQEAAALVTTFNVEIGITGAILTKLDGDSRGGAALSVKEVS-GKP 274


>3LVQ-E nrPDB
          Length = 497

 Score = 35.4 bits (80), Expect = 0.060,   Method: Compositional matrix adjust.
 Identities = 23/64 (35%), Positives = 32/64 (50%), Gaps = 5/64 (7%)

Query: 34  SIPQFTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEF 93
            I   +N    ++M+GL A GKT I  KL    +    PT  FN+     E V+YKN +F
Sbjct: 314 GIEGLSNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNV-----ETVTYKNVKF 368

Query: 94  FLPD 97
            + D
Sbjct: 369 NVWD 372


>5NZV-F nrPDB
          Length = 181

 Score = 33.9 bits (76), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 13/100 (13%)

Query: 38  FTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPD 97
           F N    ++MVGL   GKT +  KL         PT  FN+     E V YKN  F + D
Sbjct: 13  FGNKEMRILMVGLDGAGKTTVLYKLKLGEVITTIPTIGFNV-----ETVQYKNISFTVWD 67

Query: 98  NMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTR 137
                +IR            +Y  + EG + V D+ + +R
Sbjct: 68  VGGQDRIRSLW--------RHYYRNTEGVIFVVDSNDRSR 99


>4YLG-A nrPDB
          Length = 173

 Score = 33.9 bits (76), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 36/128 (28%), Positives = 52/128 (40%), Gaps = 14/128 (10%)

Query: 32  GSSIPQFTNSPTM-VIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKN 90
           GS + +      M ++MVGL A GKT I  KL         PT  FN+     E V YKN
Sbjct: 2   GSWLSKLLGKKEMRILMVGLDAAGKTSILYKLKLGEIVTTIPTIGFNV-----ETVEYKN 56

Query: 91  YEFFLPDNMEALQIR--------KQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSL 142
             F + D     +IR           A+  + D ++     E    +    N    R ++
Sbjct: 57  ISFTVWDVGGQDKIRPLWRHYYQNTQAIIFVVDSNDRDRIGEAREELMKMLNEDEMRNAI 116

Query: 143 ILQFAKEH 150
           +L FA +H
Sbjct: 117 LLVFANKH 124


>5UF8-A nrPDB
          Length = 181

 Score = 33.5 bits (75), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 24/60 (40%), Positives = 28/60 (46%), Gaps = 5/60 (8%)

Query: 38 FTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPD 97
          F N    ++MVGL A GKT I  KL         PT  FN+     E V YKN  F + D
Sbjct: 13 FGNKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV-----ETVEYKNISFTVWD 67


>2B6H-A nrPDB
          Length = 192

 Score = 33.5 bits (75), Expect = 0.22,   Method: Compositional matrix adjust.
 Identities = 34/112 (30%), Positives = 47/112 (41%), Gaps = 14/112 (12%)

Query: 31  RGSSIPQFTNSPTM-VIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYK 89
           RGS   +      M ++MVGL A GKT I  KL         PT  FN+     E V YK
Sbjct: 17  RGSLFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV-----ETVEYK 71

Query: 90  NYEFFLPDNMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRS 141
           N  F + D     +IR            +Y  + +G + V D+ +  R + S
Sbjct: 72  NICFTVWDVGGQDKIRPLW--------RHYFQNTQGLIFVVDSNDRERVQES 115


>3AQ4-A nrPDB
          Length = 184

 Score = 33.1 bits (74), Expect = 0.28,   Method: Compositional matrix adjust.
 Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 13/100 (13%)

Query: 38  FTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPD 97
           F      ++MVGL A GKT I  KL         PT  FN+     E V YKN  F + D
Sbjct: 16  FAKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV-----ETVEYKNISFTVWD 70

Query: 98  NMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTR 137
                +IR            +Y  + +G + V D+ +  R
Sbjct: 71  VGGQDKIRPLW--------RHYFQNTQGLIFVVDSNDRDR 102


>3DM5-A nrPDB
          Length = 443

 Score = 32.7 bits (73), Expect = 0.31,   Method: Compositional matrix adjust.
 Identities = 26/115 (22%), Positives = 47/115 (40%), Gaps = 16/115 (13%)

Query: 37  QFTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYR-------REAVSYK 89
           +    PT+++MVG+   GKT    KL RY    G    V     +R       R+ +   
Sbjct: 95  EIKEKPTILLMVGIQGSGKTTTVAKLARYFQKRGYKVGVVCSDTWRPGAYHQLRQLLDRY 154

Query: 90  NYEFFL-PDNMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSLI 143
           + E F  P   +A+++ K+          +Y   +   + + D     +E ++LI
Sbjct: 155 HIEVFGNPQEKDAIKLAKEGV--------DYFKSKGVDIIIVDTAGRHKEDKALI 201


>3O47-A nrPDB
          Length = 329

 Score = 32.7 bits (73), Expect = 0.32,   Method: Compositional matrix adjust.
 Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 13/100 (13%)

Query: 38  FTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPD 97
           F      ++MVGL A GKT I  KL         PT  FN+     E V YKN  F + D
Sbjct: 161 FGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV-----ETVEYKNISFTVWD 215

Query: 98  NMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTR 137
                +IR            +Y  + +G + V D+ +  R
Sbjct: 216 VGGQDKIRPLW--------RHYFQNTQGLIFVVDSNDRER 247


>5CIO-A nrPDB
          Length = 793

 Score = 32.7 bits (73), Expect = 0.37,   Method: Compositional matrix adjust.
 Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 15/100 (15%)

Query: 96  PDNMEALQIRKQCAL-AALKDVHNYLSHEEGHVAVFDATNTTRERRSLILQFAKEHGYKV 154
           P +  AL   + C L AAL+     L+H EGH++V       R +   +LQ A  HG   
Sbjct: 483 PSSHGALSEEQACGLQAALRPEAAELAHREGHLSV------ERHQGVWLLQLAGSHGLIC 536

Query: 155 FFIESI-----CNDPGII---AENIRQVKLGSPDYIDCDR 186
             +  +        P II   A N+R  +L   + I   R
Sbjct: 537 HGLNVVNRALTAQPPAIINEAARNLRHAQLKQQNDIAIRR 576


>6DFF-C nrPDB
          Length = 193

 Score = 32.3 bits (72), Expect = 0.49,   Method: Compositional matrix adjust.
 Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 15/99 (15%)

Query: 41  SPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNME 100
           S   ++MVGL A GKT I  KL         PT  FN+     E V YKN  F + D   
Sbjct: 28  SEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV-----ETVEYKNISFTVWDVGG 82

Query: 101 ALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRER 139
             +IR            +Y  + +G + V D+ +  RER
Sbjct: 83  LDKIRPLW--------RHYFQNTQGLIFVVDSND--RER 111


>5Y64-B nrPDB
          Length = 262

 Score = 32.3 bits (72), Expect = 0.52,   Method: Compositional matrix adjust.
 Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 11/79 (13%)

Query: 254 IYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQ 311
           + L RHGES  N+  R  G  D+ LS  G + A      ++  G      +TS  KR I+
Sbjct: 6   LVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQKRAIR 65

Query: 312 TAEALGVPYEQWKALNEID 330
           T          W  L+ ID
Sbjct: 66  TL---------WTVLDAID 75


>1J2J-A nrPDB
          Length = 166

 Score = 32.0 bits (71), Expect = 0.55,   Method: Compositional matrix adjust.
 Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 15/95 (15%)

Query: 45  VIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALQI 104
           ++MVGL A GKT I  KL         PT  FN+     E V YKN  F + D     +I
Sbjct: 5   ILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV-----ETVEYKNISFTVWDVGGLDKI 59

Query: 105 RKQCALAALKDVHNYLSHEEGHVAVFDATNTTRER 139
           R            +Y  + +G + V D+ +  RER
Sbjct: 60  RPLW--------RHYFQNTQGLIFVVDSND--RER 84


>6FAE-B nrPDB
          Length = 213

 Score = 32.0 bits (71), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 15/95 (15%)

Query: 45  VIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALQI 104
           ++MVGL A GKT I  KL         PT  FN+     E V YKN  F + D     +I
Sbjct: 52  ILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV-----ETVEYKNISFTVWDVGGQDKI 106

Query: 105 RKQCALAALKDVHNYLSHEEGHVAVFDATNTTRER 139
           R            +Y  + +G + V D+ +  RER
Sbjct: 107 RPLW--------RHYFQNTQGLIFVVDSND--RER 131


>4C5U-A nrPDB
          Length = 707

 Score = 32.0 bits (71), Expect = 0.67,   Method: Compositional matrix adjust.
 Identities = 19/53 (35%), Positives = 26/53 (49%), Gaps = 4/53 (7%)

Query: 384 RQENVLVICHQAVMRCLLAYFLDK----SSDELPYLKCPLHTVLKLTPVAYGC 432
           R+ N L    ++++RCLLA    K    S DELP        +L+L    YGC
Sbjct: 112 RRTNRLSELQESLIRCLLAGVFTKGCAPSVDELPATATRSAMLLRLNSFTYGC 164


>1G7S-A nrPDB
          Length = 594

 Score = 31.6 bits (70), Expect = 0.75,   Method: Compositional matrix adjust.
 Identities = 32/133 (24%), Positives = 61/133 (45%), Gaps = 12/133 (9%)

Query: 80  QYRREAVSYKNYEFFLPDNMEALQIRKQCALAALKD--VHNYLSHEEGHVAVFDATNTTR 137
           QY RE +  +      P     L+++++  L    D  +++ +  ++  +A+  + +   
Sbjct: 218 QYLREQLKIEEDS---PARGTILEVKEETGLGMTIDAVIYDGILRKDDTIAMMTSKDVIS 274

Query: 138 ER-RSLI----LQFAKEHGYKVFFIESICNDPGI--IAENIRQVKLGSPDYIDCDREKVL 190
            R RSL+    L+  +E   K   ++ +    GI  +A  I  V  GSP  +  D EKV 
Sbjct: 275 TRIRSLLKPRPLEEMRESRKKFQKVDEVVAAAGIKIVAPGIDDVMAGSPLRVVTDPEKVR 334

Query: 191 EDFLKRIECYEVN 203
           E+ L  IE  +++
Sbjct: 335 EEILSEIEDIKID 347


>1Z6X-A nrPDB
          Length = 180

 Score = 31.2 bits (69), Expect = 0.96,   Method: Compositional matrix adjust.
 Identities = 32/102 (31%), Positives = 43/102 (42%), Gaps = 15/102 (14%)

Query: 38  FTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPD 97
           F      ++MVGL A GKT I  KL         PT  FN+     E V YKN  F + D
Sbjct: 13  FGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV-----ETVEYKNICFTVWD 67

Query: 98  NMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRER 139
                +IR            +Y  + +G + V D+ +  RER
Sbjct: 68  VGGQDRIRPLW--------KHYFQNTQGLIFVVDSND--RER 99


>4UZU-A nrPDB
          Length = 513

 Score = 30.8 bits (68), Expect = 1.3,   Method: Compositional matrix adjust.
 Identities = 19/79 (24%), Positives = 38/79 (48%), Gaps = 9/79 (11%)

Query: 62  LTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALQIRKQCALAALKD------ 115
           +T   NW        N+  +R +AV +  + FF PD +  ++ +    L  + +      
Sbjct: 210 VTELKNWGKWYVNTTNIDGFRLDAVKHIKFSFF-PDWLSYVRSQTGKPLFTVGEYWSYDI 268

Query: 116 --VHNYLSHEEGHVAVFDA 132
             +HNY++  +G +++FDA
Sbjct: 269 NKLHNYITKTDGTMSLFDA 287


>5YPZ-A nrPDB
          Length = 492

 Score = 30.8 bits (68), Expect = 1.4,   Method: Compositional matrix adjust.
 Identities = 25/106 (23%), Positives = 43/106 (40%), Gaps = 15/106 (14%)

Query: 58  ISTKLTRYLNW-IGTPTKVFNLGQYRREAVSYKNYEF---FLPDNMEALQIRKQCALAAL 113
           +ST  + ++NW  GT T++F   +Y     +  NYEF   ++P           C   A+
Sbjct: 67  MSTNASEFINWGAGTSTRIFFTRKYCISTGTQGNYEFSKDYIP-----------CEEPAI 115

Query: 114 KDVHNYLSHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIES 159
               +        VA  +   +  ER   IL F K +  + F+  +
Sbjct: 116 LSNSDLKIDRIDFVATDNTVGSAIERVDFILTFDKSNANESFYFSN 161


>3LRP-A nrPDB
          Length = 181

 Score = 30.4 bits (67), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 32/104 (30%), Positives = 46/104 (44%), Gaps = 19/104 (18%)

Query: 38  FTNSPTMVIMVGLPARGKTYI--STKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFL 95
           F      ++MVGL A GKT I    KL   +  I  PT  FN+     E V ++N  F +
Sbjct: 13  FQKKDVRILMVGLDAAGKTTILYKVKLGEVVTTI--PTIGFNV-----ETVEFRNISFTV 65

Query: 96  PDNMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRER 139
            D     +IR            +Y S+ +G + V D+ +  RER
Sbjct: 66  WDVGGQDKIRPLW--------RHYYSNTDGLIFVVDSND--RER 99


>1F1O-A nrPDB
          Length = 431

 Score = 29.6 bits (65), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 9/93 (9%)

Query: 285 YALANFIQSQGISSLKVWTSHMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQE 344
           Y L  F  S  + +L V+  +MKR +     LG+ Y Q   L  ID G+  E  Y+ +Q 
Sbjct: 322 YMLNRF--SNIVKNLTVFPENMKRNMD--RTLGLIYSQRVLLALIDTGLTREEAYDTVQP 377

Query: 345 HYPEEFALRDQDKYRYRYPKGESYEDLVQRLEP 377
              E  A   Q  +R      E+ E +  RL P
Sbjct: 378 KAME--AWEKQVPFRELV---EAEEKITSRLSP 405


>3LC3-A nrPDB
          Length = 235

 Score = 29.6 bits (65), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 19/63 (30%), Positives = 26/63 (41%), Gaps = 9/63 (14%)

Query: 20  HSSGSSRLQRRRGSSIPQFTNSPTMVIMVGL-------PARGKTYISTKLTRYLNWIGTP 72
           H  G    Q   G   P  T       + G+         +GK  I TK++RY+NWI   
Sbjct: 174 HEGGRDSCQGDSGG--PHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEK 231

Query: 73  TKV 75
           TK+
Sbjct: 232 TKL 234


>1X7A-C nrPDB
          Length = 235

 Score = 29.3 bits (64), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 19/63 (30%), Positives = 26/63 (41%), Gaps = 9/63 (14%)

Query: 20  HSSGSSRLQRRRGSSIPQFTNSPTMVIMVGL-------PARGKTYISTKLTRYLNWIGTP 72
           H  G    Q   G   P  T       + G+         +GK  I TK++RY+NWI   
Sbjct: 174 HEGGKDSCQGDSGG--PHVTEVEGTSFLTGIISWGEECAVKGKYGIYTKVSRYVNWIKEK 231

Query: 73  TKV 75
           TK+
Sbjct: 232 TKL 234


>2RHQ-B nrPDB
          Length = 795

 Score = 29.3 bits (64), Expect = 4.3,   Method: Compositional matrix adjust.
 Identities = 14/51 (27%), Positives = 29/51 (56%)

Query: 331 AGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIME 381
           AG+ + +TY  + + + ++FAL+++       P  E++  L Q L P ++E
Sbjct: 509 AGLNQAITYSLVSKDHAKDFALQERPTISLLMPMSEAHATLRQSLLPHLIE 559


>3W15-A nrPDB
          Length = 368

 Score = 28.9 bits (63), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 11/115 (9%)

Query: 289 NFIQSQGISSLKVWTSHMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEH--- 345
           NF+ S    S+K+W+   K+++ T      P E  K ++ ++A + ++ ++  I ++   
Sbjct: 121 NFLSSSWDGSIKIWSPLRKQSLMTLTPR--PLEITKMVDPLNAIILKKKSFTGISKNRNC 178

Query: 346 -YPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRC 399
            Y  +F+  DQ+        G SY  L     P     + Q N LV      + C
Sbjct: 179 VYQAQFSPHDQN--LVLSCSGNSYASLFDIRLP---SGKNQNNFLVHSGLEALTC 228


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

2BIF-A nrPDB                                                          745   0.0  
1K6M-A nrPDB                                                          744   0.0  
4D4L-A nrPDB                                                          714   0.0  
2DWP-A nrPDB                                                          713   0.0  
5HTK-A nrPDB                                                          690   0.0  
5HR5-A nrPDB                                                          679   0.0  
1C7Z-A nrPDB                                                          293   1e-79
4EO9-A nrPDB                                                          227   7e-60
1RII-A nrPDB                                                          220   9e-58
1FZT-A nrPDB                                                          217   7e-57
4ODI-A nrPDB                                                          216   3e-56
3KKK-A nrPDB                                                          212   2e-55
5PGM-D nrPDB                                                          206   2e-53
1E58-A nrPDB                                                          206   3e-53
5VVE-A nrPDB                                                          202   3e-52
3PGM-A nrPDB                                                          200   1e-51
4IJ6-A nrPDB                                                          181   4e-46
6NRU-A nrPDB                                                          178   5e-45

Sequences not found previously or not previously below threshold:

3GW8-A nrPDB                                                          197   1e-50
4EMB-A nrPDB                                                          188   5e-48
5Y64-B nrPDB                                                          185   3e-47
3D8H-A nrPDB                                                          182   3e-46
5UM0-A nrPDB                                                          180   2e-45
3NFY-A nrPDB                                                          160   1e-39
4PZA-A nrPDB                                                           91   8e-19
3E9D-A nrPDB                                                           84   1e-16
3HJG-A nrPDB                                                           78   1e-14
3LG2-A nrPDB                                                           73   2e-13
3R7A-A nrPDB                                                           64   1e-10
3DCY-A nrPDB                                                           64   1e-10
2YN2-A nrPDB                                                           59   4e-09
3F2I-A nrPDB                                                           49   5e-06
6BBQ-A nrPDB                                                           44   1e-04
3LVQ-E nrPDB                                                           42   4e-04
2A5F-A nrPDB                                                           41   0.001
4YLG-A nrPDB                                                           36   0.028
3DM5-A nrPDB                                                           35   0.056
6FAE-B nrPDB                                                           35   0.065
5UF8-A nrPDB                                                           35   0.065
3O47-A nrPDB                                                           35   0.067
6DFF-C nrPDB                                                           35   0.082
1J2J-A nrPDB                                                           35   0.082
5NZV-F nrPDB                                                           35   0.084
3AQ4-A nrPDB                                                           35   0.10 
2B6H-A nrPDB                                                           33   0.22 
6E3B-A nrPDB                                                           33   0.30 
1Z6X-A nrPDB                                                           33   0.38 
3LRP-A nrPDB                                                           32   0.67 
4XRP-A nrPDB                                                           32   0.69 
4UZU-A nrPDB                                                           31   1.1  
4C0E-A nrPDB                                                           31   1.2  
1DJ3-A nrPDB                                                           31   1.2  
2YVU-A nrPDB                                                           31   1.2  
2IYT-A nrPDB                                                           31   1.3  
1LFP-A nrPDB                                                           30   1.8  
5L3R-A nrPDB                                                           30   2.0  
2SHK-A nrPDB                                                           29   5.0  
2V3C-C nrPDB                                                           28   6.6  

>2BIF-A nrPDB
          Length = 469

 Score =  745 bits (1923), Expect = 0.0,   Method: Composition-based stats.
 Identities = 347/466 (74%), Positives = 398/466 (85%), Gaps = 5/466 (1%)

Query: 7   ELTQTRLQKIWIPHSSGSSRLQ-RRRGSSIPQFTNSPTMVIMVGLPARGKTYISTKLTRY 65
           ELTQ  L+KI++P+S+G   L   +RG      TN PT+++MVGLPARGKTYIS KLTRY
Sbjct: 6   ELTQNPLKKIFMPYSNGRPALHASQRGVC---MTNCPTLIVMVGLPARGKTYISKKLTRY 62

Query: 66  LNWIGTPTKVFNLGQYRREAV-SYKNYEFFLPDNMEALQIRKQCALAALKDVHNYLSHEE 124
           LN+IG PT+ FN+GQYRR+ V +YK++EFFLPDN E L+IRKQCALAAL DV  +LS E 
Sbjct: 63  LNFIGVPTREFNVGQYRRDMVKTYKSFEFFLPDNEEGLKIRKQCALAALNDVRKFLSEEG 122

Query: 125 GHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPDYIDC 184
           GHVAVFDATNTTRERR++I  F +++GYK FF+ESIC DP +IA NI QVKLGSPDY++ 
Sbjct: 123 GHVAVFDATNTTRERRAMIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYVNR 182

Query: 185 DREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIKIFDVGTRYMVNRVQDHIQSRTVYYL 244
           D ++  EDF++RIECYE +Y+ LDEE D  LSYIKI DVG  Y+VNRV DHIQSR VYYL
Sbjct: 183 DSDEATEDFMRRIECYENSYESLDEEQDRDLSYIKIMDVGQSYVVNRVADHIQSRIVYYL 242

Query: 245 MNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLKVWTS 304
           MNIHVTPRSIYLCR GESELN++GRIGGD GLS RG++++  LA FI  Q I  LKV+TS
Sbjct: 243 MNIHVTPRSIYLCRAGESELNLKGRIGGDPGLSPRGREFSKHLAQFISDQNIKDLKVFTS 302

Query: 305 HMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPK 364
            MKRTIQTAEAL VPYEQ+K LNEIDAGVCEEMTYEEIQ+HYP EFALRDQDKYRYRYPK
Sbjct: 303 QMKRTIQTAEALSVPYEQFKVLNEIDAGVCEEMTYEEIQDHYPLEFALRDQDKYRYRYPK 362

Query: 365 GESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLK 424
           GESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDK+++ELPYLKCPLHTVLK
Sbjct: 363 GESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEELPYLKCPLHTVLK 422

Query: 425 LTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAH 470
           LTPVAYGCKVESI+LNV AVNTHR++P+NVDI+R  EEAL TVPAH
Sbjct: 423 LTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPSEEALVTVPAH 468


>1K6M-A nrPDB
          Length = 432

 Score =  744 bits (1921), Expect = 0.0,   Method: Composition-based stats.
 Identities = 427/432 (98%), Positives = 431/432 (99%)

Query: 40  NSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNM 99
           NSPTMVIMVGLPARGKTYISTKLTRYLN+IGTPTKVFNLGQYRREAVSYKNYEFFLPDNM
Sbjct: 1   NSPTMVIMVGLPARGKTYISTKLTRYLNFIGTPTKVFNLGQYRREAVSYKNYEFFLPDNM 60

Query: 100 EALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIES 159
           EALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIES
Sbjct: 61  EALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIES 120

Query: 160 ICNDPGIIAENIRQVKLGSPDYIDCDREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIK 219
           ICNDPGIIAENIRQVKLGSPDYIDCDREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIK
Sbjct: 121 ICNDPGIIAENIRQVKLGSPDYIDCDREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIK 180

Query: 220 IFDVGTRYMVNRVQDHIQSRTVYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVR 279
           IFDVGTRYMVNRVQDHIQSRTVYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVR
Sbjct: 181 IFDVGTRYMVNRVQDHIQSRTVYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVR 240

Query: 280 GKQYAYALANFIQSQGISSLKVWTSHMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTY 339
           GKQYAYALANFIQSQGISSLKV+TS MKRTIQTAEALGVPYEQ+KALNEIDAGVCEEMTY
Sbjct: 241 GKQYAYALANFIQSQGISSLKVFTSRMKRTIQTAEALGVPYEQFKALNEIDAGVCEEMTY 300

Query: 340 EEIQEHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRC 399
           EEIQEHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRC
Sbjct: 301 EEIQEHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRC 360

Query: 400 LLAYFLDKSSDELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITRE 459
           LLAYFLDKSS+ELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITRE
Sbjct: 361 LLAYFLDKSSEELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITRE 420

Query: 460 PEEALDTVPAHY 471
           PEEALDTVPAHY
Sbjct: 421 PEEALDTVPAHY 432


>4D4L-A nrPDB
          Length = 449

 Score =  714 bits (1843), Expect = 0.0,   Method: Composition-based stats.
 Identities = 321/450 (71%), Positives = 385/450 (85%), Gaps = 6/450 (1%)

Query: 7   ELTQTRLQKIWIPHSSGSSRLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYISTKLTRYL 66
           ELTQ+R+QKIW+P     S L R  G   P+ TNSPT+++MVGLPARGKTYIS KLTRYL
Sbjct: 4   ELTQSRVQKIWVPVDHRPS-LPRSCG---PKLTNSPTVIVMVGLPARGKTYISKKLTRYL 59

Query: 67  NWIGTPTKVFNLGQYRREAVS-YKNYEFFLPDNMEALQIRKQCALAALKDVHNYLSHEEG 125
           NWIG PTKVFN+G+YRREAV  Y +Y FF PDN EA+++RKQCALAAL+DV +YL+ E G
Sbjct: 60  NWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGG 119

Query: 126 HVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPDYIDCD 185
            +AVFDATNTTRERR +IL FAKE+ +K FFIES+C+DP ++A NI +VK+ SPDY DC+
Sbjct: 120 QIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCN 179

Query: 186 REKVLEDFLKRIECYEVNYQPLD-EELDSHLSYIKIFDVGTRYMVNRVQDHIQSRTVYYL 244
             + ++DF+KRI CYE +YQPLD ++ D  LS IK+ DVG R++VNRVQDHIQSR VYYL
Sbjct: 180 SAEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYL 239

Query: 245 MNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLKVWTS 304
           MNIHV PR+IYLCRHGE+E N++GRIGGDSGLS RGK++A AL+ F++ Q +  L+VWTS
Sbjct: 240 MNIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTS 299

Query: 305 HMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPK 364
            +K TIQTAEAL +PYEQWKALNEIDAGVCEE+TYEEI++ YPEE+ALR+QDKY YRYP 
Sbjct: 300 QLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPT 359

Query: 365 GESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLK 424
           GESY+DLVQRLEPVIMELERQENVLVICHQAV+RCLLAYFLDKS++E+PYLKCPLHTVLK
Sbjct: 360 GESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLK 419

Query: 425 LTPVAYGCKVESIYLNVEAVNTHREKPENV 454
           LTPVAYGC+VESIYLNVE+V THRE+ E+ 
Sbjct: 420 LTPVAYGCRVESIYLNVESVCTHRERSEDA 449


>2DWP-A nrPDB
          Length = 520

 Score =  713 bits (1841), Expect = 0.0,   Method: Composition-based stats.
 Identities = 321/450 (71%), Positives = 385/450 (85%), Gaps = 6/450 (1%)

Query: 7   ELTQTRLQKIWIPHSSGSSRLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYISTKLTRYL 66
           ELTQ+R+QKIW+P     S L R  G   P+ TNSPT+++MVGLPARGKTYIS KLTRYL
Sbjct: 4   ELTQSRVQKIWVPVDHRPS-LPRSCG---PKLTNSPTVIVMVGLPARGKTYISKKLTRYL 59

Query: 67  NWIGTPTKVFNLGQYRREAVS-YKNYEFFLPDNMEALQIRKQCALAALKDVHNYLSHEEG 125
           NWIG PTKVFN+G+YRREAV  Y +Y FF PDN EA+++RKQCALAAL+DV +YL+ E G
Sbjct: 60  NWIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLAKEGG 119

Query: 126 HVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPDYIDCD 185
            +AVFDATNTTRERR +IL FAKE+ +K FFIES+C+DP ++A NI +VK+ SPDY DC+
Sbjct: 120 QIAVFDATNTTRERRHMILHFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCN 179

Query: 186 REKVLEDFLKRIECYEVNYQPLD-EELDSHLSYIKIFDVGTRYMVNRVQDHIQSRTVYYL 244
             + ++DF+KRI CYE +YQPLD ++ D  LS IK+ DVG R++VNRVQDHIQSR VYYL
Sbjct: 180 SAEAMDDFMKRISCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYL 239

Query: 245 MNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLKVWTS 304
           MNIHV PR+IYLCRHGE+E N++GRIGGDSGLS RGK++A AL+ F++ Q +  L+VWTS
Sbjct: 240 MNIHVQPRTIYLCRHGENEHNLQGRIGGDSGLSSRGKKFASALSKFVEEQNLKDLRVWTS 299

Query: 305 HMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPK 364
            +K TIQTAEAL +PYEQWKALNEIDAGVCEE+TYEEI++ YPEE+ALR+QDKY YRYP 
Sbjct: 300 QLKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPT 359

Query: 365 GESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLK 424
           GESY+DLVQRLEPVIMELERQENVLVICHQAV+RCLLAYFLDKS++E+PYLKCPLHTVLK
Sbjct: 360 GESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLK 419

Query: 425 LTPVAYGCKVESIYLNVEAVNTHREKPENV 454
           LTPVAYGC+VESIYLNVE+V THRE+ E+ 
Sbjct: 420 LTPVAYGCRVESIYLNVESVCTHRERSEDA 449


>5HTK-A nrPDB
          Length = 505

 Score =  690 bits (1781), Expect = 0.0,   Method: Composition-based stats.
 Identities = 312/430 (72%), Positives = 369/430 (85%), Gaps = 2/430 (0%)

Query: 26  RLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREA 85
           R+  ++ S     TNSPT+++M+GLPARGKTY+S KLTRYLNWIG PTKVFNLG YRREA
Sbjct: 22  RMSEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREA 81

Query: 86  V-SYKNYEFFLPDNMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSLIL 144
           V SYK+Y+FF  DN EA++IRKQCAL AL+DV  YL+ E G +AVFDATNTTRERR +IL
Sbjct: 82  VKSYKSYDFFRHDNEEAMKIRKQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDMIL 141

Query: 145 QFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPDYIDCDREKVLEDFLKRIECYEVNY 204
            FA+++ +KVFF+ES+C+DP +IA NI +VK+ SPDY + +RE V+EDFLKRIECY+V Y
Sbjct: 142 NFAEQNSFKVFFVESVCDDPDVIAANILEVKVSSPDYPERNRENVMEDFLKRIECYKVTY 201

Query: 205 QPLD-EELDSHLSYIKIFDVGTRYMVNRVQDHIQSRTVYYLMNIHVTPRSIYLCRHGESE 263
           +PLD +  D  LS+IK+ +VG R++VNRVQD+IQS+ VYYLMNIHV PR+IYLCRHGESE
Sbjct: 202 RPLDPDNYDKDLSFIKVINVGQRFLVNRVQDYIQSKIVYYLMNIHVQPRTIYLCRHGESE 261

Query: 264 LNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQTAEALGVPYEQW 323
            N+ G+IGGDSGLSVRGKQ+A AL  F++ Q I+ LKVWTS +KRTIQTAE+LGVPYEQW
Sbjct: 262 FNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQTAESLGVPYEQW 321

Query: 324 KALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELE 383
           K LNEIDAGVCEEMTY EI++ YPEEFALRDQ+KY YRYP GESY+DLVQRLEPVIMELE
Sbjct: 322 KILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYPGGESYQDLVQRLEPVIMELE 381

Query: 384 RQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEA 443
           RQ NVLVI HQAVMRCLLAYFLDK +DELPYL+CPLHT+ KLTPVAYGCKVE+I LNVEA
Sbjct: 382 RQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYGCKVETIKLNVEA 441

Query: 444 VNTHREKPEN 453
           VNTHR+KP N
Sbjct: 442 VNTHRDKPTN 451


>5HR5-A nrPDB
          Length = 531

 Score =  679 bits (1752), Expect = 0.0,   Method: Composition-based stats.
 Identities = 312/430 (72%), Positives = 368/430 (85%), Gaps = 2/430 (0%)

Query: 26  RLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREA 85
           R+  ++ S     TNSPT+++M+GLPARGKTY+S KLTRYLNWIG PTKVFNLG YRR+A
Sbjct: 23  RISEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRRQA 82

Query: 86  V-SYKNYEFFLPDNMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSLIL 144
           V SYK+Y+FF  DN EA++IRKQCAL ALKDV  YL+ E G +AVFDATNTTRERR LIL
Sbjct: 83  VKSYKSYDFFRHDNEEAMKIRKQCALVALKDVKAYLTEESGQIAVFDATNTTRERRDLIL 142

Query: 145 QFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPDYIDCDREKVLEDFLKRIECYEVNY 204
            FA+E+ +KVFF+ES+C+DP +IA NI +VK+ SPDY + +RE V++DFLKRIECY+V Y
Sbjct: 143 NFAEENSFKVFFVESVCDDPDVIAANILEVKVSSPDYPERNRENVMDDFLKRIECYKVTY 202

Query: 205 QPLD-EELDSHLSYIKIFDVGTRYMVNRVQDHIQSRTVYYLMNIHVTPRSIYLCRHGESE 263
           QPLD +  D  LS+IK+ +VG R++VN+VQD+IQS+ VYYLMNIHV PR+IYLCRHGESE
Sbjct: 203 QPLDPDSHDKDLSFIKVINVGQRFLVNKVQDYIQSKIVYYLMNIHVHPRTIYLCRHGESE 262

Query: 264 LNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQTAEALGVPYEQW 323
            N+ G+IGGDSGLSVRGKQ+A AL  F++ Q I+ LKVWTS +KRTIQTAE+LGV YEQW
Sbjct: 263 FNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEIADLKVWTSQLKRTIQTAESLGVTYEQW 322

Query: 324 KALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELE 383
           K LNEIDAGVCEEMTY EIQE YP+EFALRD++KY YRYP GESY+DLVQRLEPVIMELE
Sbjct: 323 KILNEIDAGVCEEMTYAEIQEQYPDEFALRDEEKYLYRYPGGESYQDLVQRLEPVIMELE 382

Query: 384 RQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEA 443
           RQ NVLVI HQAVMRCLLAYFLDK +DELPYL+CPLHT+ KLTPVAYGCKVE+I LNVEA
Sbjct: 383 RQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYGCKVETIKLNVEA 442

Query: 444 VNTHREKPEN 453
           VNTHR+KP N
Sbjct: 443 VNTHRDKPTN 452


>1C7Z-A nrPDB
          Length = 191

 Score =  293 bits (750), Expect = 1e-79,   Method: Composition-based stats.
 Identities = 186/190 (97%), Positives = 189/190 (99%)

Query: 252 RSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQ 311
           RSIYLCRHGESELN+RGRIGGDSGLS RGKQYAYALANFI+SQGISSLKVWTSHMKRTIQ
Sbjct: 2   RSIYLCRHGESELNLRGRIGGDSGLSARGKQYAYALANFIRSQGISSLKVWTSHMKRTIQ 61

Query: 312 TAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDL 371
           TAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDL
Sbjct: 62  TAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDL 121

Query: 372 VQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTPVAYG 431
           VQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTPVAYG
Sbjct: 122 VQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTPVAYG 181

Query: 432 CKVESIYLNV 441
           C+VESIYLNV
Sbjct: 182 CRVESIYLNV 191


>4EO9-A nrPDB
          Length = 268

 Score =  227 bits (579), Expect = 7e-60,   Method: Composition-based stats.
 Identities = 58/235 (24%), Positives = 91/235 (38%), Gaps = 47/235 (20%)

Query: 253 SIYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTI 310
           ++ L RHGES+ N R    G  D GL+ +G+  A      +    +    ++TS ++R I
Sbjct: 29  TLILLRHGESDWNARNLFTGWVDVGLTDKGRAEAVRSGELLAEHNLLPDVLYTSLLRRAI 88

Query: 311 -------QTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRY--- 360
                   TA+ L +P  +   LNE   G  + +     +  Y EE  +  +  Y     
Sbjct: 89  TTAHLALDTADWLWIPVRRSWRLNERHYGALQGLDKAVTKARYGEERFMAWRRSYDTPPP 148

Query: 361 --------------RY------PKGESYEDLVQRLEP-----VIMELERQENVLVICHQA 395
                         RY      P  E   D+V R  P     ++ +L     VL++ H  
Sbjct: 149 PIEKGSEFSQDADPRYTDIGGGPLTECLADVVTRFLPYFTDVIVPDLRTGRTVLIVAHGN 208

Query: 396 VMRCLLAYFLDKSSDELPYLKCPLHTVLK------LTPVAYGCKVESIYLNVEAV 444
            +R L+ +  + S DE+  L  P    L+      L PV  G      YL+ EA 
Sbjct: 209 SLRALVKHLDEMSDDEVVGLNVPTGIPLRYDLDADLRPVVPG----GTYLDPEAA 259


>1RII-A nrPDB
          Length = 265

 Score =  220 bits (561), Expect = 9e-58,   Method: Composition-based stats.
 Identities = 57/233 (24%), Positives = 90/233 (38%), Gaps = 47/233 (20%)

Query: 253 SIYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTI 310
           S+ L RHGES+ N      G  D GL+ +G+  A      I    +    ++TS ++R I
Sbjct: 6   SLVLLRHGESDWNALNLFTGWVDVGLTDKGQAEAVRSGELIAEHDLLPDVLYTSLLRRAI 65

Query: 311 QTA-------EALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRY--- 360
            TA       + L +P  +   LNE   G  + +   E +  Y EE  +  +  Y     
Sbjct: 66  TTAHLALDSADRLWIPVRRSWRLNERHYGALQGLDKAETKARYGEEQFMAWRRSYDTPPP 125

Query: 361 --------------RY------PKGESYEDLVQRLEP-----VIMELERQENVLVICHQA 395
                         RY      P  E   D+V R  P     ++ +L   + VL++ H  
Sbjct: 126 PIERGSQFSQDADPRYADIGGGPLTECLADVVARFLPYFTDVIVGDLRVGKTVLIVAHGN 185

Query: 396 VMRCLLAYFLDKSSDELPYLKCPLHTVLK------LTPVAYGCKVESIYLNVE 442
            +R L+ +    S DE+  L  P    L+      + P+  G      YL+ E
Sbjct: 186 SLRALVKHLDQMSDDEIVGLNIPTGIPLRYDLDSAMRPLVRG----GTYLDPE 234


>1FZT-A nrPDB
          Length = 211

 Score =  217 bits (553), Expect = 7e-57,   Method: Composition-based stats.
 Identities = 49/216 (22%), Positives = 92/216 (42%), Gaps = 19/216 (8%)

Query: 245 MNIHVTPRSIYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVW 302
           M     P  + L RHGESE N      G  D  LS  G + A      ++S+G      +
Sbjct: 1   MTTEAAPNLLVLTRHGESEWNKLNLFTGWKDPALSETGIKEAKLGGERLKSRGYKFDIAF 60

Query: 303 TSHMKRTIQTAEAL-------GVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQ 355
           TS ++R  +T + +        +   + + LNE   G  + +  ++ ++ +  E     +
Sbjct: 61  TSALQRAQKTCQIILEEVGEPNLETIKSEKLNERYYGDLQGLNKDDARKKWGAEQVQIWR 120

Query: 356 DKYRYRYPKGESYEDLVQRLEP-----VIMELERQENVLVICHQAVMRCLLAYFLDKSSD 410
             Y    P GES +D  +R+ P     ++  + + E VL+  H   +R L+      + D
Sbjct: 121 RSYDIAPPNGESLKDTAERVLPYYKSTIVPHILKGEKVLIAAHGNSLRALIMDLEGLTGD 180

Query: 411 ELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEAVNT 446
           ++  +K  L T +   P+ Y    +  Y++ E ++ 
Sbjct: 181 QI--VKRELATGV---PIVYHLDKDGKYVSKELIDN 211


>4ODI-A nrPDB
          Length = 281

 Score =  216 bits (549), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 57/260 (21%), Positives = 93/260 (35%), Gaps = 48/260 (18%)

Query: 243 YLMNIHVTPRSIYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLK 300
           +  N+     ++ L RHGES  N   R  G  D  LS  G+Q A   A  ++ +G     
Sbjct: 10  FFGNMAKAKYTLVLIRHGESTWNKENRFTGWTDVPLSPVGEQEAVEAAKALKEKGFEFDV 69

Query: 301 VWTSHMKRTIQTA-------EALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALR 353
            +TS ++R + T        +   +P +    LNE   G  + +   E    + +E    
Sbjct: 70  AYTSVLQRAVVTCWTVLKGTDMCHIPVKSSWRLNERHYGALQGLNKAETAAKHGDEQVKI 129

Query: 354 DQDKY----------RYRYPK---------------GESYEDLVQRLEP-----VIMELE 383
            +  Y            R+P                 E  +D V+R+ P     +   + 
Sbjct: 130 WRRSYDIPPPPLEKSDKRWPGNDAVYKMVPNEALPLTECLKDTVERVLPFWFDHIAPSIM 189

Query: 384 RQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVL------KLTPV--AYGCKVE 435
             + VLV  H   +R L+ +    S + +  L  P    L       L PV   Y     
Sbjct: 190 EGKRVLVAAHGNSLRGLVKHLDKMSDEAVLELNIPTGVPLVYELDEDLQPVRHYYLLDEA 249

Query: 436 SIYLNVEAVNTH-REKPENV 454
            +   +EAV    + K EN+
Sbjct: 250 ELKAKMEAVANQGKAKGENL 269


>3KKK-A nrPDB
          Length = 258

 Score =  212 bits (540), Expect = 2e-55,   Method: Composition-based stats.
 Identities = 56/240 (23%), Positives = 96/240 (40%), Gaps = 45/240 (18%)

Query: 249 VTPRSIYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHM 306
           +T  ++ L RHGES  N   +  G  D  LS +G++ A A   +++ +      V+TS +
Sbjct: 9   MTTYTLVLLRHGESTWNKENKFTGWTDVPLSEKGEEEAIAAGKYLKEKNFKFDVVYTSVL 68

Query: 307 KRTI-------QTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQ---- 355
           KR I       +TA+ L VP  +   LNE   G  + +   E  + Y EE     +    
Sbjct: 69  KRAICTAWNVLKTADLLHVPVVKTWRLNERHCGSLQGLNKSETAKKYGEEQVKIWRRSYD 128

Query: 356 ------DKYRYRYPK---------------GESYEDLVQRLEP-----VIMELERQENVL 389
                 DK   R+P                 E  +D V+R+ P     +  ++   + V+
Sbjct: 129 IPPPKLDKEDNRWPGHNVVYKNVPKDALPFTECLKDTVERVLPFWFDHIAPDILANKKVM 188

Query: 390 VICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVL------KLTPVAYGCKVESIYLNVEA 443
           V  H   +R L+ +  + S  ++  L  P    L       L P+ +   ++S  L  + 
Sbjct: 189 VAAHGNSLRGLVKHLDNLSEADVLELNIPTGVPLVYELDENLKPIKHYYLLDSEELKKKM 248


>5PGM-D nrPDB
          Length = 246

 Score =  206 bits (524), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 54/234 (23%), Positives = 91/234 (38%), Gaps = 50/234 (21%)

Query: 254 IYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQ 311
           + L RHG+SE N +    G  D  LS +G+Q A      ++ + +    ++TS + R IQ
Sbjct: 3   LVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSRAIQ 62

Query: 312 TA-------EALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEE--------------- 349
           TA       + L +P  +   LNE   G  +     E  + + EE               
Sbjct: 63  TANIALEKADRLWIPVNRSWRLNERHYGDLQGKDKAETLKKFGEEKFNTYRRSFDVPPPP 122

Query: 350 ------FALRDQDKYRY----RYPKGESYEDLVQRLEP-----VIMELERQENVLVICHQ 394
                 F+ +  ++Y+Y      P+ ES   ++ RL P     +  +L   + V++  H 
Sbjct: 123 IDASSPFSQKGDERYKYVDPNVLPETESLALVIDRLLPYWQDVIAKDLLSGKTVMIAAHG 182

Query: 395 AVMRCLLAYFLDKSSDELPYLKCPLHTVL------KLTPVAYGCKVESIYLNVE 442
             +R L+ +    S  ++  L  P    L       L P        S YL+ E
Sbjct: 183 NSLRGLVKHLEGISDADIAKLNIPTGIPLVFELDENLKP-----SKPSYYLDPE 231


>1E58-A nrPDB
          Length = 249

 Score =  206 bits (523), Expect = 3e-53,   Method: Composition-based stats.
 Identities = 52/209 (24%), Positives = 81/209 (38%), Gaps = 39/209 (18%)

Query: 254 IYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQ 311
           + L RHGES+ N   R  G  D  LS +G   A A    ++ +G S    +TS +KR I 
Sbjct: 5   LVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKLLKEEGYSFDFAYTSVLKRAIH 64

Query: 312 TA-------EALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQ--------- 355
           T        +   +P E+   LNE   G  + +   E  E Y +E   + +         
Sbjct: 65  TLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAETAEKYGDEQVKQWRRGFAVTPPE 124

Query: 356 ---DKYRY-------------RYPKGESYEDLVQRLEP-----VIMELERQENVLVICHQ 394
              D  RY               P  ES    + R+ P     ++  ++  E V++  H 
Sbjct: 125 LTKDDERYPGHDPRYAKLSEKELPLTESLALTIDRVIPYWNETILPRMKSGERVIIAAHG 184

Query: 395 AVMRCLLAYFLDKSSDELPYLKCPLHTVL 423
             +R L+ Y  + S +E+  L  P    L
Sbjct: 185 NSLRALVKYLDNMSEEEILELNIPTGVPL 213


>5VVE-A nrPDB
          Length = 258

 Score =  202 bits (514), Expect = 3e-52,   Method: Composition-based stats.
 Identities = 50/211 (23%), Positives = 79/211 (37%), Gaps = 39/211 (18%)

Query: 252 RSIYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRT 309
             + L RHGESE N   +  G  D GLS  G + A      +  +G      +TS +KR 
Sbjct: 11  YKLVLIRHGESEWNKENKFTGWYDCGLSETGLKEAKEAGEILLKEGYEFDLCYTSFLKRA 70

Query: 310 I-------QTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRY-- 360
           I       +T +A+ +P  +   LNE   G  + +   +  E + EE     +  Y    
Sbjct: 71  IKTLWIALETMDAMYLPVVKHWRLNERHYGALQGLNKTQTAEKHGEEQVKIWRRSYDIPP 130

Query: 361 -----------------------RYPKGESYEDLVQRLEP-----VIMELERQENVLVIC 392
                                    PK ES +  V R+ P     +   ++  + VL+  
Sbjct: 131 PALEVTDERYPGHERKYQGLTQEELPKTESLKLTVDRVLPYWNDVIAPSVKEGKRVLIAA 190

Query: 393 HQAVMRCLLAYFLDKSSDELPYLKCPLHTVL 423
           H   +R L+ Y  + S +E+  L  P    L
Sbjct: 191 HGNSLRALVKYLDNISEEEIVELNIPTGVPL 221


>3PGM-A nrPDB
          Length = 244

 Score =  200 bits (509), Expect = 1e-51,   Method: Composition-based stats.
 Identities = 54/232 (23%), Positives = 93/232 (40%), Gaps = 48/232 (20%)

Query: 254 IYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQ 311
           + L RHG+SE N +    G  D  LS +G+Q A      ++ +G++ L  +TS + R IQ
Sbjct: 3   LVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKEKGVNVLVDYTSKLSRAIQ 62

Query: 312 TA-------EALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEE--------------- 349
           TA       + L +P  +   LNE   G  +     +  + + EE               
Sbjct: 63  TANIALEKADRLWIPVNRSWRLNERHYGDLQGKDKAQTLKKFGEEKFNTYRRSFDVPPPP 122

Query: 350 ------FALRDQDKYRY----RYPKGESYEDLVQRLEPVIMEL---ERQENVLVICHQAV 396
                 F+ +  ++Y+Y      P+ ES   ++ RL P   ++      +  ++  H   
Sbjct: 123 IDASSPFSQKGDERYKYVDPNVLPETESLALVIDRLLPYWQDVIAKLVGKTSMIAAHGNS 182

Query: 397 MRCLLAYFLDKSSDELPYLKCPLHTVL------KLTPVAYGCKVESIYLNVE 442
           +R L+ +    S  ++  L  P  T+L       L P        S YL+ E
Sbjct: 183 LRGLVKHLEGISDADIAKLNIPPGTILVFELDENLKP-----SKPSYYLDPE 229


>3GW8-A nrPDB
          Length = 257

 Score =  197 bits (500), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 50/222 (22%), Positives = 78/222 (35%), Gaps = 45/222 (20%)

Query: 252 RSIYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRT 309
             + L RHGES  N   R  G  D  L+ +G + A      ++  G +    +TS +KR 
Sbjct: 10  YKLVLIRHGESTWNKENRFTGWVDVDLTEQGNREARQAGQLLKEAGYTFDIAYTSVLKRA 69

Query: 310 IQT-------AEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRY-- 360
           I+T        + + VP      LNE   G    +   E    Y +E  L  +  Y    
Sbjct: 70  IRTLWHVQDQMDLMYVPVVHSWRLNERHYGALSGLNKAETAAKYGDEQVLVWRRSYDTPP 129

Query: 361 -----------------------RYPKGESYEDLVQRLEP-----VIMELERQENVLVIC 392
                                  + P  E  +D V R+ P     +   ++  + VL+  
Sbjct: 130 PALEPGDERAPYADPRYAKVPREQLPLTECLKDTVARVLPLWNESIAPAVKAGKQVLIAA 189

Query: 393 HQAVMRCLLAYFLDKSSDELPYLKCPLHTVL------KLTPV 428
           H   +R L+ Y    S  ++  L  P    L       LTP+
Sbjct: 190 HGNSLRALIKYLDGISDADIVGLNIPNGVPLVYELDESLTPI 231


>4EMB-A nrPDB
          Length = 274

 Score =  188 bits (477), Expect = 5e-48,   Method: Composition-based stats.
 Identities = 47/223 (21%), Positives = 77/223 (34%), Gaps = 44/223 (19%)

Query: 252 RSIYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRT 309
             + L RHGESE N      G  D  LS +G   A      ++ +G S    ++S + R 
Sbjct: 28  YKLVLVRHGESEWNKENLFTGWTDVKLSDKGIDEAVEAGLLLKQEGYSFDIAFSSLLSRA 87

Query: 310 IQTAEAL-------GVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRY-- 360
             T   +        +  ++   LNE   G  + +   E    Y E+  L  +  Y    
Sbjct: 88  NDTLNIILRELGQSYISVKKTWRLNERHYGALQGLNKSETAAKYGEDKVLIWRRSYDVPP 147

Query: 361 -----------------------RYPKGESYEDLVQRLEP-----VIMELERQENVLVIC 392
                                    P  E  +D V R+ P     +  E+   + V+V  
Sbjct: 148 MSLDESDDRHPIKDPRYKHIPKRELPSTECLKDTVARVIPYWTDEIAKEVLEGKKVIVAA 207

Query: 393 HQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTPVAYGCKVE 435
           H   +R L+ YF + S +++  L  P        P+ Y    +
Sbjct: 208 HGNSLRALVKYFDNLSEEDVLKLNIPTGI-----PLVYELDKD 245


>5Y64-B nrPDB
          Length = 262

 Score =  185 bits (470), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 44/234 (18%), Positives = 78/234 (33%), Gaps = 46/234 (19%)

Query: 249 VTPRSIYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHM 306
           +    + L RHGES  N+  R  G  D+ LS  G + A      ++  G      +TS  
Sbjct: 1   MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQ 60

Query: 307 KRTIQTA-------EALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYR 359
           KR I+T        + + +P  +   LNE   G    +   E    + E      +  Y 
Sbjct: 61  KRAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD 120

Query: 360 Y---------------------------RYPKGESYEDLVQRLEP-----VIMELERQEN 387
                                       + P  ES +D + R  P     ++ +++  + 
Sbjct: 121 VPPPPMEPDHPFYSNISKDRRYADLTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKR 180

Query: 388 VLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTPVAYGCKVESIYLNV 441
           VL+  H   +R ++ +    S + +  L  P        P+ Y        +  
Sbjct: 181 VLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGI-----PIVYELDKNLKPIKP 229


>3D8H-A nrPDB
          Length = 267

 Score =  182 bits (462), Expect = 3e-46,   Method: Composition-based stats.
 Identities = 48/215 (22%), Positives = 77/215 (35%), Gaps = 39/215 (18%)

Query: 250 TPRSIYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMK 307
           +   + L RHGESE N   R  G  D  LS +G   A      +  +G     V+TS +K
Sbjct: 19  STYKLTLIRHGESEWNKENRFTGWTDVSLSEQGVSEAIEAGRMLLEKGFKFDVVYTSVLK 78

Query: 308 RTIQTA-------EALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQ----- 355
           R I T          +  P      LNE   G  + +   E    + E+     +     
Sbjct: 79  RAIMTTWTVLKELGNINCPIINHWRLNERHYGALQGLNKSETASKFGEDQVKIWRRSFDV 138

Query: 356 -----DKYRYRYPK---------------GESYEDLVQRLEP-----VIMELERQENVLV 390
                +K   R+P                 E  +D V+R++P     +   +   ++VLV
Sbjct: 139 PPPVLEKSDPRWPGNELIYKGICPSCLPTTECLKDTVERVKPYFEDVIAPSIMSGKSVLV 198

Query: 391 ICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKL 425
             H   +R LL      + +++  +  P    L L
Sbjct: 199 SAHGNSLRALLYLLEGMTPEQILEVNIPTACPLVL 233


>4IJ6-A nrPDB
          Length = 211

 Score =  181 bits (460), Expect = 4e-46,   Method: Composition-based stats.
 Identities = 48/173 (27%), Positives = 82/173 (47%), Gaps = 11/173 (6%)

Query: 254 IYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKR--- 308
           + L R  ESE N  GR  G  D  LS RGK+ A  LA  +  + +    +++S +KR   
Sbjct: 4   LILVRAAESEWNPVGRYQGLLDPDLSERGKKQAKLLAQELSREHL--DVIYSSPLKRTYL 61

Query: 309 -TIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGES 367
             ++ AEA  +   +   + EID G+   M  EE+ E YPE+F    ++ ++  +  GES
Sbjct: 62  TALEIAEAKNLEVIKEDRIIEIDHGMWSGMLVEEVMEKYPEDFRRWVEEPHKVEFQGGES 121

Query: 368 YEDLVQRLEPVIMELERQ---ENVLVICHQAVMRCLLAYFLDKSSDELPYLKC 417
              +  R++  + E+ ++   + V+V+ H   MR +    L     +     C
Sbjct: 122 LASVYNRVKGFLEEVRKRHWNQTVVVVSHTVPMRAMYCALLGVDLSKFWSFGC 174


>5UM0-A nrPDB
          Length = 235

 Score =  180 bits (456), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 45/209 (21%), Positives = 76/209 (36%), Gaps = 39/209 (18%)

Query: 254 IYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQ 311
           +   RHG+SE N +    G  D  LS +G   A A    ++  G      +TS + R I+
Sbjct: 11  LVFIRHGQSEWNAKNLFTGWRDVKLSEQGLAEAAAAGKKLKENGYEFDIAFTSVLTRAIK 70

Query: 312 TA-------EALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRY---- 360
           T        + L VP  +   LNE   G  + +  ++  E Y +E     +  Y      
Sbjct: 71  TCNIVLEESDQLFVPQIKTWRLNERHYGRLQGLDKKQTAEKYGDEQVRIWRRSYDTLPPL 130

Query: 361 ---------------------RYPKGESYEDLVQRLEP-----VIMELERQENVLVICHQ 394
                                  P GE+ +  ++R+ P     +   +   + VLV  H 
Sbjct: 131 LDKDDAFSAHKDRRYAHLPADVVPDGENLKVTLERVLPFWEDQIAPAILSGKRVLVAAHG 190

Query: 395 AVMRCLLAYFLDKSSDELPYLKCPLHTVL 423
             +R L  +    S +++  L+ P    L
Sbjct: 191 NSLRALAKHIEGISDEDIMGLEIPTGQPL 219


>6NRU-A nrPDB
          Length = 206

 Score =  178 bits (451), Expect = 5e-45,   Method: Composition-based stats.
 Identities = 42/177 (23%), Positives = 82/177 (46%), Gaps = 13/177 (7%)

Query: 254 IYLCRHGESELNIRGRIGGDSG--LSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQ 311
           ++L RHGE++ N+ G   G +   L+ RG + A  L   +    +S   V  S ++R   
Sbjct: 6   LWLIRHGETQANVDGLYSGHAPTPLTARGIEQAQNLHTLLDD--VSFDLVLCSELERAQH 63

Query: 312 TAEAL----GVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYP-KGE 366
           TA  +     +P      LNE+  G  E   + ++ +   E ++    D +++  P  GE
Sbjct: 64  TARLVLSDRQLPVHIIPELNEMFFGDWEMRHHRDLMQEDAENYSAWCND-WQHAIPTNGE 122

Query: 367 SYEDLVQRLEPVIMEL---ERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLH 420
            ++   QR+E  I  L   +  +N+L++ HQ V+  L+A  +   ++ + + +    
Sbjct: 123 GFQAFSQRVERFIARLSEYQHYQNILIVSHQGVLSLLIARLIGMPAESMWHFRVDQG 179


>3NFY-A nrPDB
          Length = 267

 Score =  160 bits (405), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 45/220 (20%), Positives = 81/220 (36%), Gaps = 43/220 (19%)

Query: 249 VTPRSIYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHM 306
           ++   + + RHGE   N   R     D  L+  G + A      +++       V+TS +
Sbjct: 1   MSKYKLIMLRHGEGAWNKENRFCSWVDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSVL 60

Query: 307 KRTIQTAEAL-------GVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYR 359
            R+I TA  +        VP E    LNE   G    +  E++  ++ EE     +  Y 
Sbjct: 61  NRSIHTAWLILEELGQEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRRSYN 120

Query: 360 Y-----------------------------RYPKGESYEDLVQRLEP-----VIMELERQ 385
                                         + P+ ES +D+++RL P     +  E+ R 
Sbjct: 121 VTPPPIEESHPYYQEIYNDRRYKVCDVPLDQLPRSESLKDVLERLLPYWNERIAPEVLRG 180

Query: 386 ENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKL 425
           + +L+  H    R LL +    S +++  +  P    + L
Sbjct: 181 KTILISAHGNSSRALLKHLEGISDEDIINITLPTGVPILL 220


>4PZA-A nrPDB
          Length = 223

 Score = 91.3 bits (225), Expect = 8e-19,   Method: Composition-based stats.
 Identities = 39/164 (23%), Positives = 69/164 (42%), Gaps = 20/164 (12%)

Query: 249 VTPRSIYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHM 306
           +  R + + RHG+++ N+  R+ G  D+ LS  G+  A A A  +  +    L + +S +
Sbjct: 1   MRARRLVMLRHGQTDYNVGSRMQGQLDTELSELGRTQAVAAAEVLGKR--QPLLIVSSDL 58

Query: 307 KRTIQTA----EALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRY 362
           +R   TA    E  G+       L E   G  + +T+ +I    P    L  ++   +  
Sbjct: 59  RRAYDTAVKLGERTGLVVRVDTRLRETHLGDWQGLTHAQIDADAPGA-RLAWREDATWAP 117

Query: 363 PKGESYEDLVQRLEPVIMELERQE-----------NVLVICHQA 395
             GES  D+  R  P++ EL   E            V+++ H  
Sbjct: 118 HGGESRVDVAARSRPLVAELVASEPEWGGADEPDRPVVLVAHGG 161


>3E9D-A nrPDB
          Length = 265

 Score = 83.9 bits (206), Expect = 1e-16,   Method: Composition-based stats.
 Identities = 52/247 (21%), Positives = 89/247 (36%), Gaps = 59/247 (23%)

Query: 249 VTPRSIYLCRHGESELNIRGRIGG---DSGLSVRGKQYAYALANFIQSQGISSLKVWTSH 305
           +   ++ + RHGE++ N    + G   D+ LS  G Q A A   +++   +    V+ S+
Sbjct: 1   MLTFALTIVRHGETQYNRDKLLQGQGIDTPLSDTGHQQAAAAGRYLKD--LHFTNVFVSN 58

Query: 306 MKRTIQTAEAL--------GVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDK 357
           ++R IQTAE +                 L E   GV E    E ++           Q  
Sbjct: 59  LQRAIQTAEIILGNNLHSSATEMILDPLLRERGFGVAEGRPKEHLKNM----ANAAGQSC 114

Query: 358 YRYRYPKGESYEDLVQRLEPVIMELERQ-----------------------------ENV 388
             Y  P GE+ E +  R +  +  L ++                             +NV
Sbjct: 115 RDYTPPGGETLEQVKTRFKMFLKSLFQRMFEEHGSALSSVPSEADQPVIAGLADDGAQNV 174

Query: 389 ----LVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEAV 444
               L++ H A +R  + + ++        L+C L   LK+  V   C    I  +    
Sbjct: 175 PVHALMVSHGAFIRISVRHLVE-------DLQCCLPAGLKMNQVFSPCPNTGI--SRFIF 225

Query: 445 NTHREKP 451
             HRE+ 
Sbjct: 226 TIHREES 232


>3HJG-A nrPDB
          Length = 213

 Score = 77.8 bits (190), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 35/168 (20%), Positives = 71/168 (42%), Gaps = 10/168 (5%)

Query: 247 IHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLKVWTSHM 306
           + +   +IYL RHG+ +      + G + L V+ +     +A   +++G     + +S +
Sbjct: 1   MSLKTLNIYLMRHGKVDAAPG--LHGQTDLKVK-EAEQQQIAMAWKTKGYDVAGIISSPL 57

Query: 307 KR----TIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRY 362
            R        AE   +P      L E+D G  + M + ++   + ++     Q    +  
Sbjct: 58  SRCHDLAQILAEQQLLPMTTEDDLQEMDFGDFDGMPF-DLLTEHWKKLDAFWQSPAHHSL 116

Query: 363 PKGESYEDLVQRLEPVIMELER--QENVLVICHQAVMRCLLAYFLDKS 408
           P  ES     QR+     ++     +N+L++ H  V+R +LA+ L   
Sbjct: 117 PNAESLSTFSQRVSRAWSQIINDINDNLLIVTHGGVIRIILAHVLGVD 164


>3LG2-A nrPDB
          Length = 292

 Score = 73.1 bits (178), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 40/188 (21%), Positives = 69/188 (36%), Gaps = 32/188 (17%)

Query: 241 VYYLMNIHVTPRSIYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALAN--FIQSQGI 296
           +Y+     +TPR I   RHG++E +  G+  G  D  L+  G+          F  +Q +
Sbjct: 17  LYFQGMPSLTPRCII-VRHGQTEWSKSGQYTGLTDLPLTPYGEGQMLRTGESVFRNNQFL 75

Query: 297 SSL---KVWTSHMKRTIQTAEALGVPYEQWKA----------LNEIDAGVCEEMTYEEIQ 343
           +      ++TS   R  QT + +  P    +           L E + G  E M   EI 
Sbjct: 76  NPDNITYIFTSPRLRARQTVDLVLKPLSDEQRAKIRVVVDDDLREWEYGDYEGMLTREII 135

Query: 344 E---HYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELE----------RQENVLV 390
           E       +        +R     GE+ + +  RL   I  ++          R  +++V
Sbjct: 136 ELRKSRGLDKERPWN-IWRDGCENGETTQQIGLRLSRAIARIQNLHRKHQSEGRASDIMV 194

Query: 391 ICHQAVMR 398
             H   +R
Sbjct: 195 FAHGHALR 202


>3R7A-A nrPDB
          Length = 237

 Score = 64.3 bits (155), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 52/221 (23%), Positives = 86/221 (38%), Gaps = 42/221 (19%)

Query: 253 SIYLCRHGESELNIRGRIGG--DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTI 310
           ++Y+ RHG++ LN   R  G  DS L  +G + A  L   ++   I  +  ++S   R I
Sbjct: 15  TLYVTRHGKTILNTNHRAQGWADSPLVEKGVEVATNLGTGLKD--IHFMNAYSSDSGRAI 72

Query: 311 QTAEAL-------GVPYEQWKALNEIDAGVCEEMTYEEIQE--------HYPEEFA---- 351
           +TA  +        +  EQ K L E++ G+ E    + + +          PEE      
Sbjct: 73  ETANLVLKYSEQSKLKLEQRKKLRELNFGIFEGEKLDNMWDAVGKAAGVTSPEELLKFSI 132

Query: 352 LRDQDKYRYRYPK--GESYEDLVQRLEPVIMELER------QENVLVICHQAVMRCLLAY 403
               D  R   P    E +E    R++  I ++          NVLV+ H      L+  
Sbjct: 133 QEVIDLIRAADPTKQAEDWELFSTRIKAEIDKISEEAAKDGGGNVLVVVHG----LLITT 188

Query: 404 FLDKSSDELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEAV 444
            ++        L     +V K   + Y    + IY  VE+V
Sbjct: 189 LIEMLDSSKTKLGVENASVTK---IVY---QDGIY-TVESV 222


>3DCY-A nrPDB
          Length = 275

 Score = 63.9 bits (154), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 29/136 (21%), Positives = 50/136 (36%), Gaps = 17/136 (12%)

Query: 250 TPRSIYLCRHGESELNIRGRIGG---DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHM 306
              ++ + RHGE+  N    I G   D  LS  G + A A   F+    +     ++S +
Sbjct: 7   ARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLN--NVKFTHAFSSDL 64

Query: 307 KRTIQTAEAL--------GVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKY 358
            RT QT   +         +  +    L E   GV E     E++           ++  
Sbjct: 65  MRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAM----AKAAREECP 120

Query: 359 RYRYPKGESYEDLVQR 374
            +  P GE+ + +  R
Sbjct: 121 VFTPPGGETLDQVKMR 136


>2YN2-A nrPDB
          Length = 279

 Score = 58.9 bits (141), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 44/188 (23%), Positives = 75/188 (39%), Gaps = 23/188 (12%)

Query: 249 VTPRSIYLCRHG-ESEL----NIRGRIGG---DSGLSVRGKQYAYALANFIQSQGISSLK 300
           +   +IY+ RHG  S             G   D  LS  G + A+ LAN+I    +    
Sbjct: 10  MAIENIYIARHGYRSNWLPKGPYPPPPTGIDNDVPLSEHGVEQAHELANYISKLDVKPEM 69

Query: 301 VWTSHMKRTIQTA----EALGVPYEQWKALNE---IDAGVCEEMTYEEIQEHYPEEFALR 353
           +++S   R ++T+    EAL +P    + + E    D  +  E    E+   +       
Sbjct: 70  IFSSPFYRCLETSKPTVEALKIPLYVDRGVGEWYKPDRPIIPEPATHEVMSKFFPSMISP 129

Query: 354 DQDKYRYRYPKGESYEDLVQRLEP----VIMELERQ----ENVLVICHQAVMRCLLAYFL 405
           D +       KGE+ ED+ +R        I  +ER+    + ++++ H A    L    L
Sbjct: 130 DWEPSIIPSNKGETEEDIFERCHKFWPVFIDRVERKFPNVKTIMIVTHAATKSALGMNLL 189

Query: 406 DKSSDELP 413
             SS + P
Sbjct: 190 KFSSAKEP 197


>3F2I-A nrPDB
          Length = 172

 Score = 48.9 bits (115), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 21/63 (33%), Positives = 29/63 (46%)

Query: 254 IYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQTA 313
           +YL RHG +E    G    +  L+  GKQ    +A  +   G     + TS + R  QTA
Sbjct: 3   LYLIRHGIAEAQKTGIKDEERELTQEGKQKTEKVAYRLVKLGRQFDLIVTSPLIRARQTA 62

Query: 314 EAL 316
           E L
Sbjct: 63  EIL 65


>6BBQ-A nrPDB
          Length = 520

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 39/171 (22%), Positives = 69/171 (40%), Gaps = 19/171 (11%)

Query: 21  SSGSSRLQRRRGSSIPQ-FTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLG 79
           ++   R+  ++G  + + F N    ++M+GL A GKT I  KL    +    PT  FN+ 
Sbjct: 337 ATRKRRIANKKGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNV- 395

Query: 80  QYRREAVSYKNYEFFLPDNMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDAT-----N 134
               E V+YKN +F + D     +IR            +Y +  +G + V D       +
Sbjct: 396 ----ETVTYKNVKFNVWDVGGLDKIRPLW--------RHYYTGTQGLIFVVDCADRDRID 443

Query: 135 TTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPDYIDCD 185
             R+    I+   +     +    +  + P  +  +  Q KLG     D +
Sbjct: 444 EARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRN 494


>3LVQ-E nrPDB
          Length = 497

 Score = 42.3 bits (98), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 40/169 (23%), Positives = 65/169 (38%), Gaps = 20/169 (11%)

Query: 24  SSRLQRRRGSS--IPQFTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQY 81
            S L     +S  I   +N    ++M+GL A GKT I  KL    +    PT  FN+   
Sbjct: 302 PSALNSTASNSPGIEGLSNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNV--- 358

Query: 82  RREAVSYKNYEFFLPDNMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDAT-----NTT 136
             E V+YKN +F + D     +IR            +Y +  +G + V D       +  
Sbjct: 359 --ETVTYKNVKFNVWDVGGQDKIRPLW--------RHYYTGTQGLIFVVDCADRDRIDEA 408

Query: 137 RERRSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPDYIDCD 185
           R+    I+   +     +    +  + P  +  +  Q KLG     D +
Sbjct: 409 RQELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRN 457


>2A5F-A nrPDB
          Length = 175

 Score = 41.2 bits (95), Expect = 0.001,   Method: Composition-based stats.
 Identities = 37/153 (24%), Positives = 60/153 (39%), Gaps = 18/153 (11%)

Query: 38  FTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPD 97
           F N    ++M+GL A GKT I  KL    +    PT  FN+     E V+YKN +F + D
Sbjct: 9   FGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNV-----ETVTYKNVKFNVWD 63

Query: 98  NMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDAT-----NTTRERRSLILQFAKEHGY 152
                +IR            +Y +  +G + V D       +  R+    I+   +    
Sbjct: 64  VGGQDKIRPLW--------RHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDA 115

Query: 153 KVFFIESICNDPGIIAENIRQVKLGSPDYIDCD 185
            +    +  + P  +  +  Q KLG     D +
Sbjct: 116 IILIFANKQDLPDAMKPHEIQEKLGLTRIRDRN 148


>4YLG-A nrPDB
          Length = 173

 Score = 36.2 bits (82), Expect = 0.028,   Method: Composition-based stats.
 Identities = 27/75 (36%), Positives = 34/75 (45%), Gaps = 6/75 (8%)

Query: 32  GSSIPQFTNSPTM-VIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKN 90
           GS + +      M ++MVGL A GKT I  KL         PT  FN+     E V YKN
Sbjct: 2   GSWLSKLLGKKEMRILMVGLDAAGKTSILYKLKLGEIVTTIPTIGFNV-----ETVEYKN 56

Query: 91  YEFFLPDNMEALQIR 105
             F + D     +IR
Sbjct: 57  ISFTVWDVGGQDKIR 71


>3DM5-A nrPDB
          Length = 443

 Score = 35.4 bits (80), Expect = 0.056,   Method: Composition-based stats.
 Identities = 26/110 (23%), Positives = 45/110 (40%), Gaps = 16/110 (14%)

Query: 42  PTMVIMVGLPARGKTYISTKLTRYLNWIG-----TPTKVFNLGQY---RREAVSYKNYEF 93
           PT+++MVG+   GKT    KL RY    G       +  +  G Y   R+    Y    F
Sbjct: 100 PTILLMVGIQGSGKTTTVAKLARYFQKRGYKVGVVCSDTWRPGAYHQLRQLLDRYHIEVF 159

Query: 94  FLPDNMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSLI 143
             P   +A+++ K+          +Y   +   + + D     +E ++LI
Sbjct: 160 GNPQEKDAIKLAKEGV--------DYFKSKGVDIIIVDTAGRHKEDKALI 201


>6FAE-B nrPDB
          Length = 213

 Score = 35.0 bits (79), Expect = 0.065,   Method: Composition-based stats.
 Identities = 32/111 (28%), Positives = 47/111 (42%), Gaps = 15/111 (13%)

Query: 45  VIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALQI 104
           ++MVGL A GKT I  KL         PT  FN+     E V YKN  F + D     +I
Sbjct: 52  ILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV-----ETVEYKNISFTVWDVGGQDKI 106

Query: 105 RKQCALAALKDVHNYLSHEEGHVAVFDATNTTR--ERRSLILQFAKEHGYK 153
           R            +Y  + +G + V D+ +  R  E R  +++   E   +
Sbjct: 107 RPLW--------RHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELR 149


>5UF8-A nrPDB
          Length = 181

 Score = 35.0 bits (79), Expect = 0.065,   Method: Composition-based stats.
 Identities = 35/118 (29%), Positives = 47/118 (39%), Gaps = 15/118 (12%)

Query: 38  FTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPD 97
           F N    ++MVGL A GKT I  KL         PT  FN+     E V YKN  F + D
Sbjct: 13  FGNKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV-----ETVEYKNISFTVWD 67

Query: 98  NMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTR--ERRSLILQFAKEHGYK 153
                +IR             Y  + +G + V D+ +  R  E R  + Q   E   +
Sbjct: 68  VGGQDKIRPLW--------RYYFQNTQGIIFVVDSNDRDRIAEAREELQQMLNEDELR 117


>3O47-A nrPDB
          Length = 329

 Score = 35.0 bits (79), Expect = 0.067,   Method: Composition-based stats.
 Identities = 32/111 (28%), Positives = 47/111 (42%), Gaps = 15/111 (13%)

Query: 45  VIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALQI 104
           ++MVGL A GKT I  KL         PT  FN+     E V YKN  F + D     +I
Sbjct: 168 ILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV-----ETVEYKNISFTVWDVGGQDKI 222

Query: 105 RKQCALAALKDVHNYLSHEEGHVAVFDATNTTR--ERRSLILQFAKEHGYK 153
           R            +Y  + +G + V D+ +  R  E R  +++   E   +
Sbjct: 223 RPLW--------RHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELR 265


>6DFF-C nrPDB
          Length = 193

 Score = 34.6 bits (78), Expect = 0.082,   Method: Composition-based stats.
 Identities = 32/111 (28%), Positives = 47/111 (42%), Gaps = 15/111 (13%)

Query: 45  VIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALQI 104
           ++MVGL A GKT I  KL         PT  FN+     E V YKN  F + D     +I
Sbjct: 32  ILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV-----ETVEYKNISFTVWDVGGLDKI 86

Query: 105 RKQCALAALKDVHNYLSHEEGHVAVFDATNTTR--ERRSLILQFAKEHGYK 153
           R            +Y  + +G + V D+ +  R  E R  +++   E   +
Sbjct: 87  RPLW--------RHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELR 129


>1J2J-A nrPDB
          Length = 166

 Score = 34.6 bits (78), Expect = 0.082,   Method: Composition-based stats.
 Identities = 32/111 (28%), Positives = 47/111 (42%), Gaps = 15/111 (13%)

Query: 45  VIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALQI 104
           ++MVGL A GKT I  KL         PT  FN+     E V YKN  F + D     +I
Sbjct: 5   ILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV-----ETVEYKNISFTVWDVGGLDKI 59

Query: 105 RKQCALAALKDVHNYLSHEEGHVAVFDATNTTR--ERRSLILQFAKEHGYK 153
           R            +Y  + +G + V D+ +  R  E R  +++   E   +
Sbjct: 60  RPLW--------RHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELR 102


>5NZV-F nrPDB
          Length = 181

 Score = 34.6 bits (78), Expect = 0.084,   Method: Composition-based stats.
 Identities = 33/118 (27%), Positives = 49/118 (41%), Gaps = 15/118 (12%)

Query: 38  FTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPD 97
           F N    ++MVGL   GKT +  KL         PT  FN+     E V YKN  F + D
Sbjct: 13  FGNKEMRILMVGLDGAGKTTVLYKLKLGEVITTIPTIGFNV-----ETVQYKNISFTVWD 67

Query: 98  NMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTR--ERRSLILQFAKEHGYK 153
                +IR            +Y  + EG + V D+ + +R  E R ++ +   E   +
Sbjct: 68  VGGQDRIRSLW--------RHYYRNTEGVIFVVDSNDRSRIGEAREVMQRMLNEDELR 117


>3AQ4-A nrPDB
          Length = 184

 Score = 34.6 bits (78), Expect = 0.10,   Method: Composition-based stats.
 Identities = 32/111 (28%), Positives = 46/111 (41%), Gaps = 15/111 (13%)

Query: 45  VIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALQI 104
           ++MVGL A GKT I  KL         PT  FN+     E V YKN  F + D     +I
Sbjct: 23  ILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV-----ETVEYKNISFTVWDVGGQDKI 77

Query: 105 RKQCALAALKDVHNYLSHEEGHVAVFDATNTTR--ERRSLILQFAKEHGYK 153
           R            +Y  + +G + V D+ +  R  E R  + +   E   +
Sbjct: 78  RPLW--------RHYFQNTQGLIFVVDSNDRDRVVEARDELHRMLNEDELR 120


>2B6H-A nrPDB
          Length = 192

 Score = 33.5 bits (75), Expect = 0.22,   Method: Composition-based stats.
 Identities = 35/110 (31%), Positives = 47/110 (42%), Gaps = 16/110 (14%)

Query: 31  RGSSIPQFTNSPTM-VIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYK 89
           RGS   +      M ++MVGL A GKT I  KL         PT  FN+     E V YK
Sbjct: 17  RGSLFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV-----ETVEYK 71

Query: 90  NYEFFLPDNMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRER 139
           N  F + D     +IR            +Y  + +G + V D+ +  RER
Sbjct: 72  NICFTVWDVGGQDKIRPLW--------RHYFQNTQGLIFVVDSND--RER 111


>6E3B-A nrPDB
          Length = 169

 Score = 33.1 bits (74), Expect = 0.30,   Method: Composition-based stats.
 Identities = 21/88 (23%), Positives = 40/88 (45%), Gaps = 9/88 (10%)

Query: 347 PEEFALRDQDKYRYRYPKGESYEDLVQRL-----EPVIMELERQENVLVICHQAVMRCLL 401
           PE F+    + YR  +P+ E++  L +RL       +I E   QEN+  +     +  + 
Sbjct: 7   PENFSHVVGEIYRSSFPRQENFSFLHERLKLKSILVLIPEEYPQENLNFLK----LTGIK 62

Query: 402 AYFLDKSSDELPYLKCPLHTVLKLTPVA 429
            Y +  S ++ P++  P H + K   + 
Sbjct: 63  LYQVGMSGNKEPFVNIPSHLLTKALEIV 90


>1Z6X-A nrPDB
          Length = 180

 Score = 32.7 bits (73), Expect = 0.38,   Method: Composition-based stats.
 Identities = 31/95 (32%), Positives = 42/95 (44%), Gaps = 15/95 (15%)

Query: 45  VIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALQI 104
           ++MVGL A GKT I  KL         PT  FN+     E V YKN  F + D     +I
Sbjct: 20  ILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNV-----ETVEYKNICFTVWDVGGQDRI 74

Query: 105 RKQCALAALKDVHNYLSHEEGHVAVFDATNTTRER 139
           R            +Y  + +G + V D+ +  RER
Sbjct: 75  RPLW--------KHYFQNTQGLIFVVDSND--RER 99


>3LRP-A nrPDB
          Length = 181

 Score = 31.9 bits (71), Expect = 0.67,   Method: Composition-based stats.
 Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 15/95 (15%)

Query: 45  VIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALQI 104
           ++MVGL A GKT I  K+         PT  FN+     E V ++N  F + D     +I
Sbjct: 20  ILMVGLDAAGKTTILYKVKLGEVVTTIPTIGFNV-----ETVEFRNISFTVWDVGGQDKI 74

Query: 105 RKQCALAALKDVHNYLSHEEGHVAVFDATNTTRER 139
           R            +Y S+ +G + V D+ +  RER
Sbjct: 75  RPLW--------RHYYSNTDGLIFVVDSND--RER 99


>4XRP-A nrPDB
          Length = 312

 Score = 31.5 bits (70), Expect = 0.69,   Method: Composition-based stats.
 Identities = 27/118 (22%), Positives = 50/118 (42%), Gaps = 20/118 (16%)

Query: 42  PTMVIMVGLPARGKTYISTKLTRYL-NWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNME 100
           P ++I+VG P  GK+  +    R   NW+      F L Q+    +S     F+      
Sbjct: 11  PKLLILVGAPGSGKSTFARYFIRTEDNWVRVNRDDFRLMQFGDSLMS----PFY---EER 63

Query: 101 ALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTT-RERRSLILQFAKEHG--YKVF 155
             ++ +   +A LK+  N          + DATN++ R  + ++  + +     +KVF
Sbjct: 64  ITKMVEASVIALLKNRTN---------VIIDATNSSLRSLQDMVHTYTEYADISFKVF 112


>4UZU-A nrPDB
          Length = 513

 Score = 31.2 bits (69), Expect = 1.1,   Method: Composition-based stats.
 Identities = 19/79 (24%), Positives = 37/79 (46%), Gaps = 9/79 (11%)

Query: 62  LTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALQIRKQCALAA--------L 113
           +T   NW        N+  +R +AV +  + FF PD +  ++ +    L          +
Sbjct: 210 VTELKNWGKWYVNTTNIDGFRLDAVKHIKFSFF-PDWLSYVRSQTGKPLFTVGEYWSYDI 268

Query: 114 KDVHNYLSHEEGHVAVFDA 132
             +HNY++  +G +++FDA
Sbjct: 269 NKLHNYITKTDGTMSLFDA 287


>4C0E-A nrPDB
          Length = 528

 Score = 31.2 bits (69), Expect = 1.2,   Method: Composition-based stats.
 Identities = 11/67 (16%), Positives = 26/67 (38%), Gaps = 1/67 (1%)

Query: 20  HSSGSSRLQRRRGSSIPQFTNSPTMVIMVGLP-ARGKTYISTKLTRYLNWIGTPTKVFNL 78
                + L     +     ++   + +++GLP  +G    +  L ++L  +G   K F +
Sbjct: 181 FDMRPNLLPGFACAWAGLVSHRAFLPVILGLPDEKGWAPFTKLLEQFLGCVGELVKTFTV 240

Query: 79  GQYRREA 85
               +E 
Sbjct: 241 SSLGKEM 247


>1DJ3-A nrPDB
          Length = 442

 Score = 30.8 bits (68), Expect = 1.2,   Method: Composition-based stats.
 Identities = 27/136 (19%), Positives = 49/136 (36%), Gaps = 28/136 (20%)

Query: 273 DSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKR-TIQTAEALGVPY--EQWKALNEI 329
           D   +V G + A    +FI +        ++S + R  ++  +   +    ++   L E 
Sbjct: 126 DLHQTVDGLREAELANSFIGTTKRGIGPCYSSKVTRNGLRVCDLRHMDTFGDKLDVLFED 185

Query: 330 DAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIME-------- 381
            A   E   Y +      EE                E Y+   +RLEP I +        
Sbjct: 186 AAARFEGFKYSKGMLK--EEV---------------ERYKKFAERLEPFIADTVHVLNES 228

Query: 382 LERQENVLVICHQAVM 397
           + +++ +LV   QA M
Sbjct: 229 IRQKKKILVEGGQATM 244


>2YVU-A nrPDB
          Length = 186

 Score = 30.8 bits (68), Expect = 1.2,   Method: Composition-based stats.
 Identities = 28/108 (25%), Positives = 48/108 (44%), Gaps = 11/108 (10%)

Query: 44  MVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALQ 103
           +V + GLP  GKT I+T+L   L   G   +V + G + R  VS +   F      E L+
Sbjct: 15  VVWLTGLPGSGKTTIATRLADLLQKEGYRVEVLD-GDWARTTVS-EGAGFTR---EERLR 69

Query: 104 IRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSLILQFAKEHG 151
             K+ A  A       L    G + +    +  ++ R+++ +  +E G
Sbjct: 70  HLKRIAWIA------RLLARNGVIVICSFVSPYKQARNMVRRIVEEEG 111


>2IYT-A nrPDB
          Length = 184

 Score = 30.8 bits (68), Expect = 1.3,   Method: Composition-based stats.
 Identities = 23/83 (27%), Positives = 35/83 (42%), Gaps = 6/83 (7%)

Query: 46  IMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEAL-QI 104
           ++VGLP  GK+ I  +L + L   G      ++   +R   S    + F  D  +   +I
Sbjct: 6   VLVGLPGSGKSTIGRRLAKAL---GVGLLDTDVAIEQRTGRSIA--DIFATDGEQEFRRI 60

Query: 105 RKQCALAALKDVHNYLSHEEGHV 127
            +    AAL D    LS   G V
Sbjct: 61  EEDVVRAALADHDGVLSLGGGAV 83


>1LFP-A nrPDB
          Length = 249

 Score = 30.4 bits (67), Expect = 1.8,   Method: Composition-based stats.
 Identities = 15/85 (17%), Positives = 32/85 (37%), Gaps = 2/85 (2%)

Query: 259 HGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGIS-SLKVWTSHMKRTIQTAEALG 317
            G S              + RGK ++  +   I +  +      +   ++  I+ A+   
Sbjct: 2   AGHSHWAQIKHKKAKVD-AQRGKLFSKLIREIIVATRLGGPNPEFNPRLRTAIEQAKKAN 60

Query: 318 VPYEQWKALNEIDAGVCEEMTYEEI 342
           +P+E  +   +  AG  E   +EE+
Sbjct: 61  MPWENIERAIKKGAGELEGEQFEEV 85


>5L3R-A nrPDB
          Length = 301

 Score = 30.0 bits (66), Expect = 2.0,   Method: Composition-based stats.
 Identities = 15/45 (33%), Positives = 22/45 (48%)

Query: 42  PTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAV 86
           PT++++ GL   GKT +  KL  YL   G    +     YR  A+
Sbjct: 106 PTVILLAGLQGVGKTTVCAKLACYLKKQGKSCMLIAGDVYRPAAI 150


>2SHK-A nrPDB
          Length = 173

 Score = 28.9 bits (63), Expect = 5.0,   Method: Composition-based stats.
 Identities = 18/62 (29%), Positives = 27/62 (43%), Gaps = 3/62 (4%)

Query: 45  VIMVGLPARGKTYISTKLTRYLNWIGTPTKVF---NLGQYRREAVSYKNYEFFLPDNMEA 101
           + MVG    GKT +  +L R L +    T +F     G    + V+ + +  F     EA
Sbjct: 5   IFMVGARGCGKTTVGRELARALGYEFVDTDIFMQHTSGMTVADVVAAEGWPGFRRRESEA 64

Query: 102 LQ 103
           LQ
Sbjct: 65  LQ 66


>2V3C-C nrPDB
          Length = 432

 Score = 28.5 bits (62), Expect = 6.6,   Method: Composition-based stats.
 Identities = 13/42 (30%), Positives = 21/42 (50%)

Query: 44  MVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREA 85
           ++++VG+   GKT  + KL RY+   G    +     YR  A
Sbjct: 101 VILLVGIQGSGKTTTAAKLARYIQKRGLKPALIAADTYRPAA 142


  Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
    Posted date:  Jan 3, 2023  9:05 PM
  Number of letters in database: 10,336,785
  Number of sequences in database:  36,641
  
Lambda     K      H
   0.312    0.136    0.375 

Lambda     K      H
   0.267   0.0414    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,551,170
Number of Sequences: 36641
Number of extensions: 757514
Number of successful extensions: 2430
Number of sequences better than 10.0: 59
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 68
Number of HSP's that attempted gapping in prelim test: 2251
Number of HSP's gapped (non-prelim): 128
length of query: 471
length of database: 10,336,785
effective HSP length: 101
effective length of query: 370
effective length of database: 6,636,044
effective search space: 2455336280
effective search space used: 2455336280
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.3 bits)
S2: 61 (28.1 bits)