BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P15977 (694 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4S3P-A nrPDB 1436 0.0 5B68-A nrPDB 254 1e-67 2X1I-A nrPDB 101 1e-21 5CPT-A nrPDB 91 2e-18 2OWC-A nrPDB 90 4e-18 1X1N-A nrPDB 82 7e-16 1TZ7-A nrPDB 82 1e-15 3JWE-A nrPDB 31 2.3 4XVW-A nrPDB 29 5.9 5DJ4-A nrPDB 29 6.4 >4S3P-A nrPDB Length = 696 Score = 1436 bits (3717), Expect = 0.0, Method: Compositional matrix adjust. Identities = 689/690 (99%), Positives = 690/690 (100%) Query: 1 MESKRLDNAALAAGISPNYINAHGKPQSISAETKRRLLDAMHQRTATKVAVTPVPNVMVY 60 MESKRLDNAALAAGISPNYINAHGKPQSISAETKRRLLDAMHQRTATKVAVTPVPNVMVY Sbjct: 1 MESKRLDNAALAAGISPNYINAHGKPQSISAETKRRLLDAMHQRTATKVAVTPVPNVMVY 60 Query: 61 TSGKKMPMVVEGSGEYSWLLTTEEGTQYKGHVTGGKAFNLPTKLPEGYHTLTLTQDDQRA 120 TSGKKMPMVVEGSGEYSWLLTTEEGTQYKGHVTGGKAFNLPTKLPEGYHTLTLTQDDQRA Sbjct: 61 TSGKKMPMVVEGSGEYSWLLTTEEGTQYKGHVTGGKAFNLPTKLPEGYHTLTLTQDDQRA 120 Query: 121 HCRVIVAPKRCYEPQALLNKQKLWGACVQLYTLRSEKNWGIGDFGDLKAMLVDVAKRGGS 180 HCRVIVAPKRCYEPQALLNKQKLWGACVQLYTLRSEKNWGIGDFGDLKAMLVDVAKRGGS Sbjct: 121 HCRVIVAPKRCYEPQALLNKQKLWGACVQLYTLRSEKNWGIGDFGDLKAMLVDVAKRGGS 180 Query: 181 FIGLNPIHALYPANPESASPYSPSSRRWLNVIYIDVNAVEDFHLSEEAQAWWQLPTTQQT 240 FIGLNPIHALYPANPESASPYSPSSRRWLNVIYIDVNAVEDFHLSEEAQAWWQLPTTQQT Sbjct: 181 FIGLNPIHALYPANPESASPYSPSSRRWLNVIYIDVNAVEDFHLSEEAQAWWQLPTTQQT 240 Query: 241 LQQARDADWVDYSTVTALKMTALRMAWKGFAQRDDEQMAAFRQFVAEQGDSLFWQAAFDA 300 LQQARDADWVDYSTVTALKMTALRMAWKGFAQRDDEQMAAFRQFVAEQGDSLFWQAAFDA Sbjct: 241 LQQARDADWVDYSTVTALKMTALRMAWKGFAQRDDEQMAAFRQFVAEQGDSLFWQAAFDA 300 Query: 301 LHAQQVKEDEMRWGWPAWPEMYQNVDSPEVRQFCEEHRDDVDFYLWLQWLAYSQFAACWE 360 LHAQQVKEDEMRWGWPAWPEMYQNVDSPEVRQFCEEHRDDVDFYLWLQWLAYSQFAACWE Sbjct: 301 LHAQQVKEDEMRWGWPAWPEMYQNVDSPEVRQFCEEHRDDVDFYLWLQWLAYSQFAACWE 360 Query: 361 ISQGYEMPIGLYRDLAVGVAEGGAETWCDRELYCLKASVGAPPDILGPLGQNWGLPPMDP 420 ISQGYEMPIGLYRDLAVGVAEGGAETWCDRELYCLKASVGAPPDILGPLGQNWGLPPMDP Sbjct: 361 ISQGYEMPIGLYRDLAVGVAEGGAETWCDRELYCLKASVGAPPDILGPLGQNWGLPPMDP 420 Query: 421 HIITARAYEPFIELLRANMQNCGALRIDHVMSMLRLWWIPYGETADQGAYVHYPVDDLLS 480 HIITARAYEPFIELLRANMQNCGALRIDHVMSMLRLWWIPYGETADQGAYVHYPVDDLLS Sbjct: 421 HIITARAYEPFIELLRANMQNCGALRIDHVMSMLRLWWIPYGETADQGAYVHYPVDDLLS 480 Query: 481 ILALESKRHRCMVIGEDLGTVPVEIVGKLRSSGVYSYKVLYFENDHEKTFRAPKAYPEQS 540 ILALESKRHRCMVIGEDLGTVPVEIVGKLRSSGVYSYKVLYFENDHEKTFRAPKAYPEQS Sbjct: 481 ILALESKRHRCMVIGEDLGTVPVEIVGKLRSSGVYSYKVLYFENDHEKTFRAPKAYPEQS 540 Query: 541 MAVAATHDLPTLRGYWECGDLTLGKTLGLYPDEVVLRGLYQDRELAKQGLLDALHKYGCL 600 MAVAATHDLPTLRGYWECGDLTLGKTLGLYPDEVVLRGLYQDRELAKQGLLDALHKYGCL Sbjct: 541 MAVAATHDLPTLRGYWECGDLTLGKTLGLYPDEVVLRGLYQDRELAKQGLLDALHKYGCL 600 Query: 601 PKRAGHKASLMSMTPTLNRGLQRYIADSNSALLGLQPEDWLDMAEPVNIPGTSYQYKNWR 660 PKRAGHKASLMSMTPTLNRGLQRYIADSNSALLGLQPEDWLDMAEPVNIPGTSYQYKNWR Sbjct: 601 PKRAGHKASLMSMTPTLNRGLQRYIADSNSALLGLQPEDWLDMAEPVNIPGTSYQYKNWR 660 Query: 661 RKLSATLESMFADDGVNKLLKDLDRRRRAA 690 RKLSATLESMFADDGVNKLLKDLDRRRR+A Sbjct: 661 RKLSATLESMFADDGVNKLLKDLDRRRRSA 690 >5B68-A nrPDB Length = 714 Score = 254 bits (648), Expect = 1e-67, Method: Compositional matrix adjust. Identities = 194/646 (30%), Positives = 297/646 (45%), Gaps = 51/646 (7%) Query: 35 RRLLDAMHQRTATKVAVTPVPNVMVYTSGKKM--PMVVEGSGEYSWLLTTEEGTQ----- 87 +R + H R T+ P+P +V G ++ P+ V + E+GTQ Sbjct: 58 QRQIALFHDREFTR----PLPPSVVAVEGDELVFPVHVHDGSPADVHIELEDGTQRDVSQ 113 Query: 88 ---------YKGHVTGGKAFNLPTKLPEGYHTLTLTQDDQRAHCRVIVAPKRCYEPQALL 138 G G +F +P LP G+H L L +++ A C +I+ P R L Sbjct: 114 VENWTAPREIDGIRWGEASFKIPGDLPLGWHKLHLKSNERSAECGLIITPARLSTADKYL 173 Query: 139 NKQKLWGACVQLYTLRSEKNWGIGDFGDLKAMLVDVAKRGGSFIGLNPIHALYPANPESA 198 + + G Q+Y++RS +WG+GDF DL + VA+ G F+ +NP+HA P P Sbjct: 174 DSPR-SGVMAQIYSVRSTLSWGMGDFNDLGNLASVVAQDGADFLLINPMHAAEPLPPTED 232 Query: 199 SPYSPSSRRWLNVIYIDVNAVEDFHLSEEAQAWWQLPTTQQTLQQARDADWVDYSTVTAL 258 SPY P++RR++N IYI V + +F+ E + ++ +D ++ + V A Sbjct: 233 SPYLPTTRRFINPIYIRVEDIPEFNQLEIDLRDDIAEMAAEFRERNLTSDIIERNDVYAA 292 Query: 259 KMTALRMAWKGFAQRDDEQMAAFRQFVAEQGDSLFWQAAFDALHAQQVKEDEMRWGWPAW 318 K+ LR ++ R E+ A F FV +G L A W A Sbjct: 293 KLQVLRAIFE--MPRSSEREANFVSFVQREGQGLIDFAT-----------------WCAD 333 Query: 319 PEMYQNVDSPEVRQFCEEHRDDVD-FYLWLQWLAYSQFAACWEISQGYEMPIGLYRDLAV 377 E Q+ E E RD++ FY+WLQWL Q AA + + M IG+ DLAV Sbjct: 334 RETAQS----ESVHGTEPDRDELTMFYMWLQWLCDEQLAAAQKRAVDAGMSIGIMADLAV 389 Query: 378 GVAEGGAETWCDRELYCLKASVGAPPDILGPLGQNWGLPPMDPHIITARAYEPFIELLRA 437 GV GGA+ + ASVGAPPD GQ+W PP P + Y P+ LLR Sbjct: 390 GVHPGGADAQNLSHVLAPDASVGAPPDGYNQQGQDWSQPPWHPVRLAEEGYIPWRNLLRT 449 Query: 438 NMQNCGALRIDHVMSMLRLWWIPYGETADQGAYVHYPVDDLLSILALESKRHRCMVIGED 497 +++ G +R+DHV+ + RL+ +P ++ G Y+ + + L+ ILALE++ +VIGED Sbjct: 450 VLRHSGGIRVDHVLGLFRLFVMPRMQSPATGTYIRFDHNALVGILALEAELAGAVVIGED 509 Query: 498 LGTVPVEIVGKLRSSGVYSYKVLYFEND-HEKTFRAPKAYPEQSMAVAATHDLPTLRGYW 556 LGT + L G+ +L+FE+ + R + Y ++ THDLP GY Sbjct: 510 LGTFEPWVQDALAQRGIMGTSILWFEHSPSQPGPRRQEEYRPLALTTVTTHDLPPTAGYL 569 Query: 557 ECGDLTLGKTLGLYPDEVVLRGLYQDRELAKQGLLDALHKYGCLPKR--AGHKASLMSMT 614 E + L + LG+ + L +D + + +LD LP R G + Sbjct: 570 EGEHIALRERLGVLNTDPAAE-LAEDLQWQAE-ILDVAASANALPAREYVGLERDQRGEL 627 Query: 615 PTLNRGLQRYIADSNSALLGLQPEDWLDMAEPVNIPGTSYQ-YKNW 659 L GL ++A + SAL + D + N PGT+ Y NW Sbjct: 628 AELLEGLHTFVAKTPSALTCVCLVDMVGEKRAQNQPGTTRDMYPNW 673 >2X1I-A nrPDB Length = 500 Score = 101 bits (251), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 90/321 (28%), Positives = 137/321 (42%), Gaps = 22/321 (6%) Query: 250 VDYSTVTALKMTALRMAWKGFAQR-DDEQMAAFRQFVAEQGDSLFWQAAFDALHAQQVKE 308 VDY + A K ALR A++GF Q+ E+ F +F E+ L A F L + Sbjct: 95 VDYGLLYAWKWPALRAAFQGFRQKASPEEKEDFARFQEEEAWWLRDYALFMTLKSHHGGL 154 Query: 309 DEMRWGWPAWPEMYQNVDSPEVRQFCEEHRDDVDFYLWLQWLAYSQFAACWEISQGYEMP 368 W AWP + + +++ +++ F+ + QWL + Q+ A E ++ + Sbjct: 155 P-----WNAWPLALRTREERALKEAEASLAEEIAFHAFTQWLFFRQWGALKEEAEA--LG 207 Query: 369 IGLYRDLAVGVAEGGAETWCDRELYCLKAS------VGAPPDILGPLGQNWGLPPMDPHI 422 I D+ + VAE AE W E + L G PPD GQ WG P + Sbjct: 208 IAFIGDMPIFVAEDSAEVWAHPEWFHLDEEGRPTVVAGVPPDYFSETGQRWGNPLYRWEV 267 Query: 423 ITARAYEPFIELLRANMQNCGALRIDHVMSMLRLWWIPYG-ETADQGAYVHYPVDDLLSI 481 + + +I LR ++ +RIDH W IP TA +G +V P + L + Sbjct: 268 LEEEGFSFWIARLRKALELFHLVRIDHFRGFEAYWEIPASCPTAVEGRWVKAPGEKLFA- 326 Query: 482 LALESKRHRCMVIGEDLGTVPVEIVGKLRSSGVYSYKVLY--FENDHEKTFRAPKAYPEQ 539 ++ R ++ EDLG + E+ G+ KVL F+N E F P YPE Sbjct: 327 -RIQEAFGRIPILAEDLGVITPEVEALRDRFGLPGMKVLQFAFDNGMENPF-LPHNYPEH 384 Query: 540 SMAVA--ATHDLPTLRGYWEC 558 V THD T G++ Sbjct: 385 GRVVVYTGTHDNDTTLGWYRT 405 >5CPT-A nrPDB Length = 564 Score = 90.5 bits (223), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 96/415 (23%), Positives = 160/415 (38%), Gaps = 41/415 (9%) Query: 160 GIGDFGDLKAMLVDVAKRGGSFIGLNPIHALYPANPESASPYSPSSRRWLNVIYIDVNA- 218 GIGD G+ +D G + + L P + E SPY+ N + I ++ Sbjct: 86 GIGDLGEEAFRFIDWLHSTGCSVW--QVLPLVPPD-EGGSPYAGQDANCGNTLLISLDEL 142 Query: 219 VEDFHLSEEAQAWWQLPTTQQTLQQARDADWVDYSTVTALKMTALRMAWKGFAQRDDEQM 278 V+D L + L Q DAD V+Y T LK + A K + E Sbjct: 143 VKDGLL------------IKDELPQPIDADSVNYQTANKLKSPLITKAAKRLIDGNGELK 190 Query: 279 AAFRQFVAEQGDSLFWQAAFDALHAQQVKEDEMRWGWPAWPEMYQNVDSPEVRQFCEEHR 338 + F + S + + DA + + + W WPE +N + E + Sbjct: 191 SKLLDFRNDPSISCWLE---DAAYFAAIDNTLNAYSWFEWPEPLKNRHLSALEAIYESQK 247 Query: 339 DDVDFYLWLQWLAYSQFAACWEISQGYEMPIGLYRDLAVGVAEGGAETWCDRELYCLKAS 398 + +D ++ Q+L Q+ E ++ + + D+ + V A+ W +++ + L Sbjct: 248 EFIDLFIAKQFLFQRQWQKVREYAR--RQGVDIMGDMPIYVGYHSADVWANKKHFLLNKK 305 Query: 399 ------VGAPPDILGPLGQNWGLPPMDPHIITARAYEPFIELLRANMQNCGALRIDHVMS 452 G PPD+ GQ WG P D + + Y ++ +R RIDH Sbjct: 306 GFPLLVSGVPPDLFSETGQLWGSPLYDWKAMESDQYSWWVNRIRRAQDLYDECRIDHFRG 365 Query: 453 MLRLWWIPY-GETADQGAYVHYPVDDLLSILALESKRHRCMVIGEDLGTVPVEIVGKLRS 511 W +P + A G + P L A+ + +I EDLG + ++V +S Sbjct: 366 FAGFWAVPSEAKVAMVGRWKVGPGKSLFD--AISKGVGKIKIIAEDLGVITKDVVELRKS 423 Query: 512 SGVYSYKVLYF------ENDHEKTFRAPKAYPEQSMAVAATHDLPTLRGYWECGD 560 G VL F +N H P + + + THD T+RG+W+ D Sbjct: 424 IGAPGMAVLQFAFGGGADNPH-----LPHNHEVNQVVYSGTHDNDTIRGWWDTLD 473 >2OWC-A nrPDB Length = 503 Score = 89.7 bits (221), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 86/324 (26%), Positives = 133/324 (41%), Gaps = 28/324 (8%) Query: 250 VDYSTVTALKMTALRMAWKGFAQR----DDEQMAAFRQFVAEQGDSLFWQAAFDALHAQQ 305 VDY + A K AL+ A++GF ++ + E AAFR+ A +W + A + Sbjct: 98 VDYGLLYAWKWPALKEAFRGFKEKASPEEREAFAAFREREA------WWLEDYALFMALK 151 Query: 306 VKEDEMRWGWPAWPEMYQNVDSPEVRQFCEEHRDDVDFYLWLQWLAYSQFAACWEISQGY 365 + W WP + + +R+ ++V F+ + QWL + Q+ A ++ Sbjct: 152 GAHGGLPWN--RWPLPLRKREEKALREAKSALAEEVAFHAFTQWLFFRQWGAL--KAEAE 207 Query: 366 EMPIGLYRDLAVGVAEGGAETWCDRELYCLKAS------VGAPPDILGPLGQNWGLPPMD 419 + I + D+ + VAE AE W E + L G PPD GQ WG P Sbjct: 208 ALGIRIIGDMPIFVAEDSAEVWAHPEWFHLDEEGRPTVVAGVPPDYFSETGQRWGNPLYR 267 Query: 420 PHIITARAYEPFIELLRANMQNCGALRIDHVMSMLRLWWIPYG-ETADQGAYVHYPVDDL 478 ++ + +I L ++ +RIDH W IP TA +G +V P + L Sbjct: 268 WDVLEREGFSFWIRRLEKALELFHLVRIDHFRGFEAYWEIPASCPTAVEGRWVKAPGEKL 327 Query: 479 LSILALESKRHRCMVIGEDLGTVPVEIVGKLRSSGVYSYKVLYFENDH--EKTFRAPKAY 536 ++ V+ EDLG + E+ G+ KVL F D E F P Y Sbjct: 328 FQ--KIQEVFGEVPVLAEDLGVITPEVEALRDRFGLPGMKVLQFAFDDGMENPF-LPHNY 384 Query: 537 PEQSMAVA--ATHDLPTLRGYWEC 558 P V THD T G++ Sbjct: 385 PAHGRVVVYTGTHDNDTTLGWYRT 408 >1X1N-A nrPDB Length = 524 Score = 82.0 bits (201), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 97/429 (22%), Positives = 160/429 (37%), Gaps = 41/429 (9%) Query: 146 ACVQLYTLRSEKNWGIGDFGDLKAMLVD-VAKRGGSFIGLNPIHALYPANPESASPYSPS 204 A + L+ +GIGD G +D + G S + P+ E SPYS Sbjct: 28 AGILLHPTSFPGPYGIGDLGPQAFKFLDWLHLAGCSLWQVLPLVPPGKRGNEDGSPYSGQ 87 Query: 205 SRRWLNVIYIDVNAVEDFHLSEEAQAWWQLPTTQQTLQQARDADWVDYSTVTALKMTALR 264 N + I + + D L + + LPT D V+YST++ +K + Sbjct: 88 DANCGNTLLISLEELVDDGLLKMEELPEPLPT-----------DRVNYSTISEIKDPLIT 136 Query: 265 MAWKGFAQRDDEQMAAFRQFVAEQGDSLFWQAAFDALHAQQVKEDEMRWGWPAWPEMYQN 324 A K + E F + S + + DA + + W WPE +N Sbjct: 137 KAAKRLLSSEGELKDQLENFRRDPNISSWLE---DAAYFAAIDNSVNTISWYDWPEPLKN 193 Query: 325 VDSPEVRQFCEEHRDDVDFYLWLQWLAYSQFAACWEISQGYEMP--IGLYRDLAVGVAEG 382 + + + +D +D ++ Q+L F W+ + Y I + D+ + V Sbjct: 194 RHLAALEEVYQSEKDFIDIFIAQQFL----FQRQWKKVRDYARSKGISIMGDMPIYVGYH 249 Query: 383 GAETWCDRELYCLKAS------VGAPPDILGPLGQNWGLPPMDPHIITARAYEPFIELLR 436 A+ W +++ + L G PPD GQ WG P D + + ++ ++ Sbjct: 250 SADVWANKKQFLLNRKGFPLIVSGVPPDAFSETGQLWGSPLYDWKAMEKDGFSWWVRRIQ 309 Query: 437 ANMQNCGALRIDHVMSMLRLWWIPYGE-TADQGAYVHYPVDDLLSILALESKRHRCMVIG 495 RIDH W +P E A G + P L A+ + +I Sbjct: 310 RATDLFDEFRIDHFRGFAGFWAVPSEEKIAILGRWKVGPGKPLFD--AILQAVGKINIIA 367 Query: 496 EDLGTVPVEIVGKLRSSGVYSYKVLYF------ENDHEKTFRAPKAYPEQSMAVAATHDL 549 EDLG + ++V +S VL F EN H P + + + THD Sbjct: 368 EDLGVITEDVVQLRKSIEAPGMAVLQFAFGSDAENPH-----LPHNHEQNQVVYTGTHDN 422 Query: 550 PTLRGYWEC 558 T+RG+W+ Sbjct: 423 DTIRGWWDT 431 >1TZ7-A nrPDB Length = 505 Score = 81.6 bits (200), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 103/422 (24%), Positives = 171/422 (40%), Gaps = 41/422 (9%) Query: 146 ACVQLYTLRSEKNWGIGDFGDLKAMLVDVAKRGGSFIGLNPIHALYPANPESA-SPYSPS 204 A + L+ +GIGD G +D K G L + L P + E+ SPYS + Sbjct: 24 AGILLHVTSLPSPYGIGDLGKEAYRFLDFLKECG--FSLWQVLPLNPTSLEAGNSPYSSN 81 Query: 205 SRRWLNVIYIDVNAVEDFHLSEEAQAWWQLPTTQQTLQQARDADWVDYSTVTALKMTALR 264 S N + ID + + L +E + P + Y V K L Sbjct: 82 SLFAGNYVLIDPEELLEEDLIKERDLK-RFPLGEAL-----------YEVVYEYKKELLE 129 Query: 265 MAWKGFAQRDDEQMAAFRQFVAEQGDSLFWQAAFDALHAQQVKEDEMRWGWPAWPEMYQN 324 A+K F + F+ E L A + A+ ++ KE W W E + Sbjct: 130 KAFKNF-----RRFELLEDFLKEHSYWLRDYALYMAIKEEEGKE------WYEWDEELKR 178 Query: 325 VDSPEVRQFCEEHRDDVDFYLWLQWLAYSQFAACWEISQGY--EMPIGLYRDLAVGVAEG 382 + +++ + + F++++Q++ + Q WE + Y E I + DL + + Sbjct: 179 REKEALKRVLNKLKGRFYFHVFVQFVFFKQ----WEKLRRYARERGISIVGDLPMYPSYS 234 Query: 383 GAETWCDRELYCLKASV------GAPPDILGPLGQNWGLPPMDPHIITARAYEPFIELLR 436 A+ W + EL+ L + G PPD GQ WG P + + +I + Sbjct: 235 SADVWTNPELFKLDGDLKPLFVAGVPPDFFSKTGQLWGNPVYNWEEHEKEGFRWWIRRVL 294 Query: 437 ANMQNCGALRIDHVMSMLRLWWIPYG-ETADQGAYVHYPVDDLLSILALESKRHRCMVIG 495 N++ LR+DH W +PYG ETA G +V P L L S + I Sbjct: 295 HNLKLFDFLRLDHFRGFEAYWEVPYGEETAVNGRWVKAPGKTLFKKLL--SYFPKNPFIA 352 Query: 496 EDLGTVPVEIVGKLRSSGVYSYKVLYFENDHEKTFRAPKAYPEQSMAVAATHDLPTLRGY 555 EDLG + E+ + + +V+ F +++ P E ++ +THDLP +RG+ Sbjct: 353 EDLGFITDEVRYLRETFKIPGSRVIEFAFYDKESEHLPHNVEENNVYYTSTHDLPPIRGW 412 Query: 556 WE 557 +E Sbjct: 413 FE 414 >3JWE-A nrPDB Length = 320 Score = 30.8 bits (68), Expect = 2.3, Method: Compositional matrix adjust. Identities = 15/42 (35%), Positives = 25/42 (59%) Query: 171 LVDVAKRGGSFIGLNPIHALYPANPESASPYSPSSRRWLNVI 212 ++ A+R G F G+ I L ANPESA+ + + + LN++ Sbjct: 146 ILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLV 187 >4XVW-A nrPDB Length = 224 Score = 29.3 bits (64), Expect = 5.9, Method: Composition-based stats. Identities = 14/36 (38%), Positives = 22/36 (61%) Query: 272 QRDDEQMAAFRQFVAEQGDSLFWQAAFDALHAQQVK 307 ++ DEQ A FRQ +A + D+L+ AA + A+ K Sbjct: 38 KKADEQQAQFRQALASEHDALYNDAASPRIGAKDAK 73 >5DJ4-A nrPDB Length = 480 Score = 29.3 bits (64), Expect = 6.4, Method: Compositional matrix adjust. Identities = 20/80 (25%), Positives = 32/80 (40%), Gaps = 3/80 (3%) Query: 1 MESKRLDNAALAAGISPNYINAHGKPQSISAETKRRLLDAMHQRTATKVAVTPVPNVMVY 60 M S R+DN A+ G+ P+Y + + + T L + A A + Y Sbjct: 71 MSSGRVDNLAVVMGLHPDYFTSFWRLHYLLLHTDGPLASSWRHYIAIMAAAR---HQCSY 127 Query: 61 TSGKKMPMVVEGSGEYSWLL 80 G M ++ G+ WLL Sbjct: 128 LVGSHMAEFLQTGGDPEWLL 147 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4S3P-A nrPDB 1100 0.0 5B68-A nrPDB 751 0.0 1X1N-A nrPDB 498 e-141 5CPT-A nrPDB 491 e-139 1TZ7-A nrPDB 453 e-127 2X1I-A nrPDB 443 e-124 2OWC-A nrPDB 432 e-121 Sequences not found previously or not previously below threshold: 6C94-A nrPDB 37 0.040 1G9R-A nrPDB 34 0.19 4AIE-A nrPDB 33 0.37 3ERB-A nrPDB 31 1.4 1XGN-A nrPDB 31 1.9 2DBY-A nrPDB 31 2.8 5D6O-A nrPDB 30 2.9 6Q8C-A nrPDB 29 5.0 3WEN-A nrPDB 29 6.3 CONVERGED! >4S3P-A nrPDB Length = 696 Score = 1100 bits (2844), Expect = 0.0, Method: Composition-based stats. Identities = 689/690 (99%), Positives = 690/690 (100%) Query: 1 MESKRLDNAALAAGISPNYINAHGKPQSISAETKRRLLDAMHQRTATKVAVTPVPNVMVY 60 MESKRLDNAALAAGISPNYINAHGKPQSISAETKRRLLDAMHQRTATKVAVTPVPNVMVY Sbjct: 1 MESKRLDNAALAAGISPNYINAHGKPQSISAETKRRLLDAMHQRTATKVAVTPVPNVMVY 60 Query: 61 TSGKKMPMVVEGSGEYSWLLTTEEGTQYKGHVTGGKAFNLPTKLPEGYHTLTLTQDDQRA 120 TSGKKMPMVVEGSGEYSWLLTTEEGTQYKGHVTGGKAFNLPTKLPEGYHTLTLTQDDQRA Sbjct: 61 TSGKKMPMVVEGSGEYSWLLTTEEGTQYKGHVTGGKAFNLPTKLPEGYHTLTLTQDDQRA 120 Query: 121 HCRVIVAPKRCYEPQALLNKQKLWGACVQLYTLRSEKNWGIGDFGDLKAMLVDVAKRGGS 180 HCRVIVAPKRCYEPQALLNKQKLWGACVQLYTLRSEKNWGIGDFGDLKAMLVDVAKRGGS Sbjct: 121 HCRVIVAPKRCYEPQALLNKQKLWGACVQLYTLRSEKNWGIGDFGDLKAMLVDVAKRGGS 180 Query: 181 FIGLNPIHALYPANPESASPYSPSSRRWLNVIYIDVNAVEDFHLSEEAQAWWQLPTTQQT 240 FIGLNPIHALYPANPESASPYSPSSRRWLNVIYIDVNAVEDFHLSEEAQAWWQLPTTQQT Sbjct: 181 FIGLNPIHALYPANPESASPYSPSSRRWLNVIYIDVNAVEDFHLSEEAQAWWQLPTTQQT 240 Query: 241 LQQARDADWVDYSTVTALKMTALRMAWKGFAQRDDEQMAAFRQFVAEQGDSLFWQAAFDA 300 LQQARDADWVDYSTVTALKMTALRMAWKGFAQRDDEQMAAFRQFVAEQGDSLFWQAAFDA Sbjct: 241 LQQARDADWVDYSTVTALKMTALRMAWKGFAQRDDEQMAAFRQFVAEQGDSLFWQAAFDA 300 Query: 301 LHAQQVKEDEMRWGWPAWPEMYQNVDSPEVRQFCEEHRDDVDFYLWLQWLAYSQFAACWE 360 LHAQQVKEDEMRWGWPAWPEMYQNVDSPEVRQFCEEHRDDVDFYLWLQWLAYSQFAACWE Sbjct: 301 LHAQQVKEDEMRWGWPAWPEMYQNVDSPEVRQFCEEHRDDVDFYLWLQWLAYSQFAACWE 360 Query: 361 ISQGYEMPIGLYRDLAVGVAEGGAETWCDRELYCLKASVGAPPDILGPLGQNWGLPPMDP 420 ISQGYEMPIGLYRDLAVGVAEGGAETWCDRELYCLKASVGAPPDILGPLGQNWGLPPMDP Sbjct: 361 ISQGYEMPIGLYRDLAVGVAEGGAETWCDRELYCLKASVGAPPDILGPLGQNWGLPPMDP 420 Query: 421 HIITARAYEPFIELLRANMQNCGALRIDHVMSMLRLWWIPYGETADQGAYVHYPVDDLLS 480 HIITARAYEPFIELLRANMQNCGALRIDHVMSMLRLWWIPYGETADQGAYVHYPVDDLLS Sbjct: 421 HIITARAYEPFIELLRANMQNCGALRIDHVMSMLRLWWIPYGETADQGAYVHYPVDDLLS 480 Query: 481 ILALESKRHRCMVIGEDLGTVPVEIVGKLRSSGVYSYKVLYFENDHEKTFRAPKAYPEQS 540 ILALESKRHRCMVIGEDLGTVPVEIVGKLRSSGVYSYKVLYFENDHEKTFRAPKAYPEQS Sbjct: 481 ILALESKRHRCMVIGEDLGTVPVEIVGKLRSSGVYSYKVLYFENDHEKTFRAPKAYPEQS 540 Query: 541 MAVAATHDLPTLRGYWECGDLTLGKTLGLYPDEVVLRGLYQDRELAKQGLLDALHKYGCL 600 MAVAATHDLPTLRGYWECGDLTLGKTLGLYPDEVVLRGLYQDRELAKQGLLDALHKYGCL Sbjct: 541 MAVAATHDLPTLRGYWECGDLTLGKTLGLYPDEVVLRGLYQDRELAKQGLLDALHKYGCL 600 Query: 601 PKRAGHKASLMSMTPTLNRGLQRYIADSNSALLGLQPEDWLDMAEPVNIPGTSYQYKNWR 660 PKRAGHKASLMSMTPTLNRGLQRYIADSNSALLGLQPEDWLDMAEPVNIPGTSYQYKNWR Sbjct: 601 PKRAGHKASLMSMTPTLNRGLQRYIADSNSALLGLQPEDWLDMAEPVNIPGTSYQYKNWR 660 Query: 661 RKLSATLESMFADDGVNKLLKDLDRRRRAA 690 RKLSATLESMFADDGVNKLLKDLDRRRR+A Sbjct: 661 RKLSATLESMFADDGVNKLLKDLDRRRRSA 690 >5B68-A nrPDB Length = 714 Score = 751 bits (1938), Expect = 0.0, Method: Composition-based stats. Identities = 194/646 (30%), Positives = 297/646 (45%), Gaps = 51/646 (7%) Query: 35 RRLLDAMHQRTATKVAVTPVPNVMVYTSGKKM--PMVVEGSGEYSWLLTTEEGTQ----- 87 +R + H R T+ P+P +V G ++ P+ V + E+GTQ Sbjct: 58 QRQIALFHDREFTR----PLPPSVVAVEGDELVFPVHVHDGSPADVHIELEDGTQRDVSQ 113 Query: 88 ---------YKGHVTGGKAFNLPTKLPEGYHTLTLTQDDQRAHCRVIVAPKRCYEPQALL 138 G G +F +P LP G+H L L +++ A C +I+ P R L Sbjct: 114 VENWTAPREIDGIRWGEASFKIPGDLPLGWHKLHLKSNERSAECGLIITPARLSTADKYL 173 Query: 139 NKQKLWGACVQLYTLRSEKNWGIGDFGDLKAMLVDVAKRGGSFIGLNPIHALYPANPESA 198 + + G Q+Y++RS +WG+GDF DL + VA+ G F+ +NP+HA P P Sbjct: 174 DSPR-SGVMAQIYSVRSTLSWGMGDFNDLGNLASVVAQDGADFLLINPMHAAEPLPPTED 232 Query: 199 SPYSPSSRRWLNVIYIDVNAVEDFHLSEEAQAWWQLPTTQQTLQQARDADWVDYSTVTAL 258 SPY P++RR++N IYI V + +F+ E + ++ +D ++ + V A Sbjct: 233 SPYLPTTRRFINPIYIRVEDIPEFNQLEIDLRDDIAEMAAEFRERNLTSDIIERNDVYAA 292 Query: 259 KMTALRMAWKGFAQRDDEQMAAFRQFVAEQGDSLFWQAAFDALHAQQVKEDEMRWGWPAW 318 K+ LR ++ R E+ A F FV +G L A W A Sbjct: 293 KLQVLRAIFE--MPRSSEREANFVSFVQREGQGLIDFAT-----------------WCAD 333 Query: 319 PEMYQNVDSPEVRQFCEEHRDDVD-FYLWLQWLAYSQFAACWEISQGYEMPIGLYRDLAV 377 E Q+ E E RD++ FY+WLQWL Q AA + + M IG+ DLAV Sbjct: 334 RETAQS----ESVHGTEPDRDELTMFYMWLQWLCDEQLAAAQKRAVDAGMSIGIMADLAV 389 Query: 378 GVAEGGAETWCDRELYCLKASVGAPPDILGPLGQNWGLPPMDPHIITARAYEPFIELLRA 437 GV GGA+ + ASVGAPPD GQ+W PP P + Y P+ LLR Sbjct: 390 GVHPGGADAQNLSHVLAPDASVGAPPDGYNQQGQDWSQPPWHPVRLAEEGYIPWRNLLRT 449 Query: 438 NMQNCGALRIDHVMSMLRLWWIPYGETADQGAYVHYPVDDLLSILALESKRHRCMVIGED 497 +++ G +R+DHV+ + RL+ +P ++ G Y+ + + L+ ILALE++ +VIGED Sbjct: 450 VLRHSGGIRVDHVLGLFRLFVMPRMQSPATGTYIRFDHNALVGILALEAELAGAVVIGED 509 Query: 498 LGTVPVEIVGKLRSSGVYSYKVLYFEN-DHEKTFRAPKAYPEQSMAVAATHDLPTLRGYW 556 LGT + L G+ +L+FE+ + R + Y ++ THDLP GY Sbjct: 510 LGTFEPWVQDALAQRGIMGTSILWFEHSPSQPGPRRQEEYRPLALTTVTTHDLPPTAGYL 569 Query: 557 ECGDLTLGKTLGLYPDEVVLRGLYQDRELAKQGLLDALHKYGCLPKR--AGHKASLMSMT 614 E + L + LG+ + L +D + + +LD LP R G + Sbjct: 570 EGEHIALRERLGVLNTDPAAE-LAEDLQWQAE-ILDVAASANALPAREYVGLERDQRGEL 627 Query: 615 PTLNRGLQRYIADSNSALLGLQPEDWLDMAEPVNIPGTSYQ-YKNW 659 L GL ++A + SAL + D + N PGT+ Y NW Sbjct: 628 AELLEGLHTFVAKTPSALTCVCLVDMVGEKRAQNQPGTTRDMYPNW 673 >1X1N-A nrPDB Length = 524 Score = 498 bits (1283), Expect = e-141, Method: Composition-based stats. Identities = 98/449 (21%), Positives = 167/449 (37%), Gaps = 31/449 (6%) Query: 146 ACVQLYTLRSEKNWGIGDFGDLKAMLVDVAK-RGGSFIGLNPIHALYPANPESASPYSPS 204 A + L+ +GIGD G +D G S + P+ E SPYS Sbjct: 28 AGILLHPTSFPGPYGIGDLGPQAFKFLDWLHLAGCSLWQVLPLVPPGKRGNEDGSPYSGQ 87 Query: 205 SRRWLNVIYIDVNAVEDFHLSEEAQAWWQLPTTQQTLQQARDADWVDYSTVTALKMTALR 264 N + I + + D L + + LPT D V+YST++ +K + Sbjct: 88 DANCGNTLLISLEELVDDGLLKMEELPEPLPT-----------DRVNYSTISEIKDPLIT 136 Query: 265 MAWKGFAQRDDEQMAAFRQFVAEQGDSLFWQAAFDALHAQQVKEDEMRWGWPAWPEMYQN 324 A K + E F + S + + DA + + W WPE +N Sbjct: 137 KAAKRLLSSEGELKDQLENFRRDPNISSWLE---DAAYFAAIDNSVNTISWYDWPEPLKN 193 Query: 325 VDSPEVRQFCEEHRDDVDFYLWLQWLAYSQFAACWEISQGYEMPIGLYRDLAVGVAEGGA 384 + + + +D +D ++ Q+L Q+ + ++ I + D+ + V A Sbjct: 194 RHLAALEEVYQSEKDFIDIFIAQQFLFQRQWKKVRDYAR--SKGISIMGDMPIYVGYHSA 251 Query: 385 ETWCDRELYCLKAS------VGAPPDILGPLGQNWGLPPMDPHIITARAYEPFIELLRAN 438 + W +++ + L G PPD GQ WG P D + + ++ ++ Sbjct: 252 DVWANKKQFLLNRKGFPLIVSGVPPDAFSETGQLWGSPLYDWKAMEKDGFSWWVRRIQRA 311 Query: 439 MQNCGALRIDHVMSMLRLWWIPYGE-TADQGAYVHYPVDDLLSILALESKRHRCMVIGED 497 RIDH W +P E A G + P L A+ + +I ED Sbjct: 312 TDLFDEFRIDHFRGFAGFWAVPSEEKIAILGRWKVGPGKPLFD--AILQAVGKINIIAED 369 Query: 498 LGTVPVEIVGKLRSSGVYSYKVLYFEN-DHEKTFRAPKAYPEQSMAVAATHDLPTLRGYW 556 LG + ++V +S VL F + P + + + THD T+RG+W Sbjct: 370 LGVITEDVVQLRKSIEAPGMAVLQFAFGSDAENPHLPHNHEQNQVVYTGTHDNDTIRGWW 429 Query: 557 EC----GDLTLGKTLGLYPDEVVLRGLYQ 581 + + K L +E + RGL + Sbjct: 430 DTLPQEEKSNVLKYLSNIEEEEISRGLIE 458 >5CPT-A nrPDB Length = 564 Score = 491 bits (1263), Expect = e-139, Method: Composition-based stats. Identities = 95/423 (22%), Positives = 159/423 (37%), Gaps = 29/423 (6%) Query: 146 ACVQLYTLRSEKNWGIGDFGDLKAMLVDVAKRGGSFIGLNPIHALYPANPESASPYSPSS 205 A V L+ GIGD G+ +D G + + L P + E SPY+ Sbjct: 72 AGVLLHPTSFRGPHGIGDLGEEAFRFIDWLHSTGC--SVWQVLPLVPPD-EGGSPYAGQD 128 Query: 206 RRWLNVIYIDVNAVEDFHLSEEAQAWWQLPTTQQTLQQARDADWVDYSTVTALKMTALRM 265 N + I ++ + L + L Q DAD V+Y T LK + Sbjct: 129 ANCGNTLLISLDELVKDGLL-----------IKDELPQPIDADSVNYQTANKLKSPLITK 177 Query: 266 AWKGFAQRDDEQMAAFRQFVAEQGDSLFWQAAFDALHAQQVKEDEMRWGWPAWPEMYQNV 325 A K + E + F + S + + DA + + + W WPE +N Sbjct: 178 AAKRLIDGNGELKSKLLDFRNDPSISCWLE---DAAYFAAIDNTLNAYSWFEWPEPLKNR 234 Query: 326 DSPEVRQFCEEHRDDVDFYLWLQWLAYSQFAACWEISQGYEMPIGLYRDLAVGVAEGGAE 385 + E ++ +D ++ Q+L Q+ E ++ + + D+ + V A+ Sbjct: 235 HLSALEAIYESQKEFIDLFIAKQFLFQRQWQKVREYARR--QGVDIMGDMPIYVGYHSAD 292 Query: 386 TWCDRELYCLKAS------VGAPPDILGPLGQNWGLPPMDPHIITARAYEPFIELLRANM 439 W +++ + L G PPD+ GQ WG P D + + Y ++ +R Sbjct: 293 VWANKKHFLLNKKGFPLLVSGVPPDLFSETGQLWGSPLYDWKAMESDQYSWWVNRIRRAQ 352 Query: 440 QNCGALRIDHVMSMLRLWWIPY-GETADQGAYVHYPVDDLLSILALESKRHRCMVIGEDL 498 RIDH W +P + A G + P L A+ + +I EDL Sbjct: 353 DLYDECRIDHFRGFAGFWAVPSEAKVAMVGRWKVGPGKSLFD--AISKGVGKIKIIAEDL 410 Query: 499 GTVPVEIVGKLRSSGVYSYKVLYFEN-DHEKTFRAPKAYPEQSMAVAATHDLPTLRGYWE 557 G + ++V +S G VL F P + + + THD T+RG+W+ Sbjct: 411 GVITKDVVELRKSIGAPGMAVLQFAFGGGADNPHLPHNHEVNQVVYSGTHDNDTIRGWWD 470 Query: 558 CGD 560 D Sbjct: 471 TLD 473 >1TZ7-A nrPDB Length = 505 Score = 453 bits (1164), Expect = e-127, Method: Composition-based stats. Identities = 102/430 (23%), Positives = 171/430 (39%), Gaps = 37/430 (8%) Query: 146 ACVQLYTLRSEKNWGIGDFGDLKAMLVDVAKRGGSFIGLNPIHALYPANPESA-SPYSPS 204 A + L+ +GIGD G +D K G L + L P + E+ SPYS + Sbjct: 24 AGILLHVTSLPSPYGIGDLGKEAYRFLDFLKECG--FSLWQVLPLNPTSLEAGNSPYSSN 81 Query: 205 SRRWLNVIYIDVNAVEDFHLSEEAQAWWQLPTTQQTLQQARDADWVDYSTVTALKMTALR 264 S N + ID + + L +E + P + Y V K L Sbjct: 82 SLFAGNYVLIDPEELLEEDLIKERDLK-RFPLGEAL-----------YEVVYEYKKELLE 129 Query: 265 MAWKGFAQRDDEQMAAFRQFVAEQGDSLFWQAAFDALHAQQVKEDEMRWGWPAWPEMYQN 324 A+K F + F+ E L A + A+ ++ KE W W E + Sbjct: 130 KAFKNF-----RRFELLEDFLKEHSYWLRDYALYMAIKEEEGKE------WYEWDEELKR 178 Query: 325 VDSPEVRQFCEEHRDDVDFYLWLQWLAYSQFAACWEISQGYEMPIGLYRDLAVGVAEGGA 384 + +++ + + F++++Q++ + Q+ ++ E I + DL + + A Sbjct: 179 REKEALKRVLNKLKGRFYFHVFVQFVFFKQWEKLRRYAR--ERGISIVGDLPMYPSYSSA 236 Query: 385 ETWCDRELYCLKAS------VGAPPDILGPLGQNWGLPPMDPHIITARAYEPFIELLRAN 438 + W + EL+ L G PPD GQ WG P + + +I + N Sbjct: 237 DVWTNPELFKLDGDLKPLFVAGVPPDFFSKTGQLWGNPVYNWEEHEKEGFRWWIRRVLHN 296 Query: 439 MQNCGALRIDHVMSMLRLWWIPYG-ETADQGAYVHYPVDDLLSILALESKRHRCMVIGED 497 ++ LR+DH W +PYG ETA G +V P L L S + I ED Sbjct: 297 LKLFDFLRLDHFRGFEAYWEVPYGEETAVNGRWVKAPGKTLFKKLL--SYFPKNPFIAED 354 Query: 498 LGTVPVEIVGKLRSSGVYSYKVLYFENDHEKTFRAPKAYPEQSMAVAATHDLPTLRGYWE 557 LG + E+ + + +V+ F +++ P E ++ +THDLP +RG++E Sbjct: 355 LGFITDEVRYLRETFKIPGSRVIEFAFYDKESEHLPHNVEENNVYYTSTHDLPPIRGWFE 414 Query: 558 CGDLTLGKTL 567 K L Sbjct: 415 NLGEESRKRL 424 >2X1I-A nrPDB Length = 500 Score = 443 bits (1138), Expect = e-124, Method: Composition-based stats. Identities = 106/424 (25%), Positives = 164/424 (38%), Gaps = 38/424 (8%) Query: 147 CVQLYTLRSEKNWGIGDFGDLKAMLVDVAKRGGSFIGLNPIHALYPANPESASPYSPSSR 206 + L+ WG+G G+ + K G+ + L P SPY S Sbjct: 8 GLLLHPTSLPGPWGVGVLGEEARGFLRFLKEAGARY--WQVLPLGPTGY-GDSPYQSFSA 64 Query: 207 RWLNVIYIDVNAVEDFHLSEEAQAWWQLPTTQQTLQQARDADWVDYSTVTALKMTALRMA 266 N ID+ + D + VDY + A K ALR A Sbjct: 65 FAGNPYLIDLRPLVDRGFVRLEDPGFP-------------EGRVDYGLLYAWKWPALRAA 111 Query: 267 WKGFAQR-DDEQMAAFRQFVAEQGDSLFWQAAFDALHAQQVKEDEMRWGWPAWPEMYQNV 325 ++GF Q+ E+ F +F E+ L A F L + W AWP + Sbjct: 112 FQGFRQKASPEEKEDFARFQEEEAWWLRDYALFMTLKSHHGGLP-----WNAWPLALRTR 166 Query: 326 DSPEVRQFCEEHRDDVDFYLWLQWLAYSQFAACWEISQGYEMPIGLYRDLAVGVAEGGAE 385 + +++ +++ F+ + QWL + Q+ A E ++ + I D+ + VAE AE Sbjct: 167 EERALKEAEASLAEEIAFHAFTQWLFFRQWGALKEEAE--ALGIAFIGDMPIFVAEDSAE 224 Query: 386 TWCDRELYCLKAS------VGAPPDILGPLGQNWGLPPMDPHIITARAYEPFIELLRANM 439 W E + L G PPD GQ WG P ++ + +I LR + Sbjct: 225 VWAHPEWFHLDEEGRPTVVAGVPPDYFSETGQRWGNPLYRWEVLEEEGFSFWIARLRKAL 284 Query: 440 QNCGALRIDHVMSMLRLWWIPYG-ETADQGAYVHYPVDDLLSILALESKRHRCMVIGEDL 498 + +RIDH W IP TA +G +V P + L + ++ R ++ EDL Sbjct: 285 ELFHLVRIDHFRGFEAYWEIPASCPTAVEGRWVKAPGEKLFA--RIQEAFGRIPILAEDL 342 Query: 499 GTVPVEIVGKLRSSGVYSYKVLY--FENDHEKTFRAPKAYPEQS--MAVAATHDLPTLRG 554 G + E+ G+ KVL F+N E F P YPE + THD T G Sbjct: 343 GVITPEVEALRDRFGLPGMKVLQFAFDNGMENPF-LPHNYPEHGRVVVYTGTHDNDTTLG 401 Query: 555 YWEC 558 ++ Sbjct: 402 WYRT 405 >2OWC-A nrPDB Length = 503 Score = 432 bits (1111), Expect = e-121, Method: Composition-based stats. Identities = 99/423 (23%), Positives = 154/423 (36%), Gaps = 36/423 (8%) Query: 147 CVQLYTLRSEKNWGIGDFGDLKAMLVDVAKRGGSFIGLNPIHALYPANPESASPYSPSSR 206 + L+ +G+G G + K G + L P SPY S Sbjct: 11 GLLLHPTSLPGPYGVGVLGQEARDFLRFLKEAGGRY--WQVLPLGPTGY-GDSPYQSFSA 67 Query: 207 RWLNVIYIDVNAVEDFHLSEEAQAWWQLPTTQQTLQQARDADWVDYSTVTALKMTALRMA 266 N ID+ + + + VDY + A K AL+ A Sbjct: 68 FAGNPYLIDLRPLAERGYVRLEDPGFP-------------QGRVDYGLLYAWKWPALKEA 114 Query: 267 WKGFAQR-DDEQMAAFRQFVAEQGDSLFWQAAFDALHAQQVKEDEMRWGWPAWPEMYQNV 325 ++GF ++ E+ AF F + L A F AL W WP + Sbjct: 115 FRGFKEKASPEEREAFAAFREREAWWLEDYALFMALKGAHGGLP-----WNRWPLPLRKR 169 Query: 326 DSPEVRQFCEEHRDDVDFYLWLQWLAYSQFAACWEISQGYEMPIGLYRDLAVGVAEGGAE 385 + +R+ ++V F+ + QWL + Q+ A ++ + I + D+ + VAE AE Sbjct: 170 EEKALREAKSALAEEVAFHAFTQWLFFRQWGAL--KAEAEALGIRIIGDMPIFVAEDSAE 227 Query: 386 TWCDRELYCLKAS------VGAPPDILGPLGQNWGLPPMDPHIITARAYEPFIELLRANM 439 W E + L G PPD GQ WG P ++ + +I L + Sbjct: 228 VWAHPEWFHLDEEGRPTVVAGVPPDYFSETGQRWGNPLYRWDVLEREGFSFWIRRLEKAL 287 Query: 440 QNCGALRIDHVMSMLRLWWIPYG-ETADQGAYVHYPVDDLLSILALESKRHRCMVIGEDL 498 + +RIDH W IP TA +G +V P + L ++ V+ EDL Sbjct: 288 ELFHLVRIDHFRGFEAYWEIPASCPTAVEGRWVKAPGEKLFQ--KIQEVFGEVPVLAEDL 345 Query: 499 GTVPVEIVGKLRSSGVYSYKVLYFENDH-EKTFRAPKAYPEQS--MAVAATHDLPTLRGY 555 G + E+ G+ KVL F D + P YP + THD T G+ Sbjct: 346 GVITPEVEALRDRFGLPGMKVLQFAFDDGMENPFLPHNYPAHGRVVVYTGTHDNDTTLGW 405 Query: 556 WEC 558 + Sbjct: 406 YRT 408 >6C94-A nrPDB Length = 497 Score = 36.7 bits (83), Expect = 0.040, Method: Composition-based stats. Identities = 36/221 (16%), Positives = 58/221 (26%), Gaps = 35/221 (15%) Query: 221 DFHLSEEAQAWWQLPTTQQTLQQARDA----DWVDYSTVTALKMTALRMAWKGFAQRDDE 276 D +W P ++ L+ R A D V AL+ R + +R + Sbjct: 205 DSFQYHNDFIYWLTPHGRRFLRACRAAHDHTDRVIRQRKAALQDEKEREKIQN--RRHLD 262 Query: 277 QMAAFRQFVAEQGDSLFW---QAAFDALHAQQVKEDEMRWGWPAWPEMYQNVDSPEVRQF 333 + E G L +A D + W + R+ Sbjct: 263 FLDILLDVRGESGVQLSDTDLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQQRCREE 322 Query: 334 CEEHRDDVDFYLWLQWL---------------------AYSQFAACWEISQGYEMPIGLY 372 E D D + W Y Q + G +P G Sbjct: 323 VREILGDQDSFQWEDLAKMTYLTMCMKECFRLYPPVPQVYRQLSKPVSFVDGRSLPAGSL 382 Query: 373 RDLAVGVAEGGAETWCDREL-----YCLKASVGAPPDILGP 408 L + ++ W D E+ + + S G P P Sbjct: 383 ISLHIYALHRNSDVWPDPEVFDPLRFSPENSSGRHPYAFIP 423 >1G9R-A nrPDB Length = 311 Score = 34.4 bits (77), Expect = 0.19, Method: Composition-based stats. Identities = 34/147 (23%), Positives = 50/147 (34%), Gaps = 23/147 (15%) Query: 530 FRAPKAYPEQSMAVAATHDLPTLRGYWECGDLTLGKTLGLYPDEVVL----------RGL 579 F+ + EQ V D L G ++ G P L Sbjct: 170 FKMSSEWVEQYKDVMQYQDQDILNGLFKGGVCYANSRFNFMPTNYAFMANWFASRHTDPL 229 Query: 580 YQDRELAKQGLLDALHKYGCLPKRAGHKASLMSMTPTLNRGLQRYIADSNSALLGLQPED 639 Y+DR ++ + C P + H T G +R+ + S L PE+ Sbjct: 230 YRDR---TNTVMPVAVSHYCGPAKPWH----RDCTAW---GAERFTELAGS--LTTVPEE 277 Query: 640 WLD-MAEPVNIPGTSYQYKNWRRKLSA 665 W +A P + T + WRRKLSA Sbjct: 278 WRGKLAVPHRMFSTKRMLQRWRRKLSA 304 >4AIE-A nrPDB Length = 549 Score = 33.2 bits (74), Expect = 0.37, Method: Composition-based stats. Identities = 32/168 (19%), Positives = 60/168 (35%), Gaps = 24/168 (14%) Query: 149 QLYTLRSEKNWG--IGDFGDLKAMLVDVAKRGGSFIGLNPIHALYPANPESASPYSPSSR 206 Q+Y + + G IGD + + L + K G I L+P++ +P + Y S Sbjct: 14 QVYPKSFQDSNGDGIGDLQGIISRLDYLEKLGIDAIWLSPVY----QSPGVDNGYDISDY 69 Query: 207 RWLNVIYIDVNAVEDFHLSEEAQAWWQLPTTQQTLQQARDADWV---------DYSTVTA 257 ++ Y + + D +S+ + ++ + W Y Sbjct: 70 EAIDPQYGTMADM-DELISKAKEHHIKIVMDLVVNHTSDQHKWFVEAKKGKDNQYRDYYI 128 Query: 258 LKMTA-------LRMAWKGFAQRDDEQMAA-FRQFVAEQGDSLFWQAA 297 + L+ A+ G A + DE+ + F A+Q L WQ Sbjct: 129 WRDPVDEHEPNDLKSAFSGSAWKYDERSGQYYLHFFADQQPDLNWQNT 176 >3ERB-A nrPDB Length = 223 Score = 31.3 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 21/74 (28%), Gaps = 7/74 (9%) Query: 530 FRAPKAYPEQSMAVAATHDLPTLRGYWECGDLTLGKTLGLYPDEVVLRGLYQDRELAKQG 589 P+ +H G+ LT GLYP R + G Sbjct: 2 PSCPQNVNISGGTFTLSH------GWAPGSLLTYSCPQGLYPS-PASRLCKSSGQWQTPG 54 Query: 590 LLDALHKYGCLPKR 603 +L K C P R Sbjct: 55 ATRSLSKAVCKPVR 68 >1XGN-A nrPDB Length = 295 Score = 30.9 bits (68), Expect = 1.9, Method: Composition-based stats. Identities = 25/121 (20%), Positives = 43/121 (35%), Gaps = 11/121 (9%) Query: 1 MESKRLDNAALAAGIS-PNYINAHGKPQSISAETKRRLLDAMHQRTATKVAVTPVPNVMV 59 + +++ L AGIS PN H + E ++ T V VP ++ Sbjct: 150 LSGHKIERYKLHAGISIPNIYRPHD--NYVLKEGDVFAIEPF--ATIGAGQVIEVPPTLI 205 Query: 60 YTSGKKMPMVVEGSGEYSWLLTTEEGTQYKGHVTGGKAFNLPTKLPEGYHTLTLTQDDQR 119 Y + +P+ V + + E GT + L +PEG L L ++ Sbjct: 206 YMYVRDVPVRVAQARFLLAKIKREYGTLPFAYRW------LQNDMPEGQLKLALKTLEKA 259 Query: 120 A 120 Sbjct: 260 G 260 >2DBY-A nrPDB Length = 368 Score = 30.5 bits (67), Expect = 2.8, Method: Composition-based stats. Identities = 6/50 (12%), Positives = 14/50 (28%) Query: 424 TARAYEPFIELLRANMQNCGALRIDHVMSMLRLWWIPYGETADQGAYVHY 473 + + G + D +R IP+ + + G + Sbjct: 292 EKEVRAWTVRRGTKAPRAAGEIHSDMERGFIRAEVIPWDKLVEAGGWARA 341 >5D6O-A nrPDB Length = 349 Score = 30.1 bits (66), Expect = 2.9, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 17/46 (36%) Query: 72 GSGEYSWLLTTEEGTQYKGHVTGGKAFNLPTKLPEGYHTLTLTQDD 117 GEYS +G + + H+ F+ E + L L + Sbjct: 193 NGGEYSSHEEVADGLRRQSHLWAAMGFSTEFWKQEAWRRLGLESKE 238 >6Q8C-A nrPDB Length = 877 Score = 29.4 bits (64), Expect = 5.0, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 18/68 (26%), Gaps = 4/68 (5%) Query: 294 WQAAFDALHAQQVKEDEMRWGWPAWPEMYQNVDSPEVRQFCEEHRDDVD----FYLWLQW 349 W A +K + W Y + + R+ +Y W QW Sbjct: 80 WDAFGMPAENAAMKNNVAPAAWTYDNIEYMKTQLKSLGFAVDWEREVATCKPEYYRWEQW 139 Query: 350 LAYSQFAA 357 L F Sbjct: 140 LFTKLFEK 147 >3WEN-A nrPDB Length = 913 Score = 29.4 bits (64), Expect = 6.3, Method: Composition-based stats. Identities = 9/47 (19%), Positives = 16/47 (34%), Gaps = 2/47 (4%) Query: 404 DILGPLGQNWGLPPMDPHIITARAYEPFIELLRANMQNC--GALRID 448 D LG W P P + A +++ ++ + ID Sbjct: 423 DGNPYLGSVWPGPVYYPDFLDPAARSFWVDEIKRFRDILPIDGIWID 469 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.126 0.341 Lambda K H 0.267 0.0381 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,521,485 Number of Sequences: 36641 Number of extensions: 1014856 Number of successful extensions: 2516 Number of sequences better than 10.0: 18 Number of HSP's better than 10.0 without gapping: 19 Number of HSP's successfully gapped in prelim test: 9 Number of HSP's that attempted gapping in prelim test: 2416 Number of HSP's gapped (non-prelim): 32 length of query: 694 length of database: 10,336,785 effective HSP length: 104 effective length of query: 590 effective length of database: 6,526,121 effective search space: 3850411390 effective search space used: 3850411390 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 62 (28.6 bits)