BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P15848 (533 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1FSU-A nrPDB 1020 0.0 6BIA-A nrPDB 211 7e-55 4FDJ-A nrPDB 161 7e-40 3ED4-A nrPDB 149 2e-36 4CXU-A nrPDB 142 4e-34 1E2S-P nrPDB 141 6e-34 1P49-A nrPDB 123 2e-28 2QZU-A nrPDB 91 1e-18 5G2V-A nrPDB 81 1e-15 4UPI-A nrPDB 67 2e-11 6IOZ-A nrPDB 67 2e-11 4MHX-A nrPDB 66 3e-11 4UPL-A nrPDB 57 2e-08 2W8S-A nrPDB 56 4e-08 4UPH-A nrPDB 51 1e-06 2VQR-A nrPDB 51 2e-06 3LXQ-A nrPDB 49 4e-06 4UOP-A nrPDB 39 0.004 4UPK-A nrPDB 39 0.005 4UG4-A nrPDB 37 0.024 5FBY-A nrPDB 31 1.1 5UDY-A nrPDB 31 1.5 4KXA-A nrPDB 30 2.7 5VEN-A nrPDB 30 2.7 4UOO-A nrPDB 30 2.7 4PXL-B nrPDB 30 2.9 4LR2-A nrPDB 29 4.1 4N31-A nrPDB 29 5.1 5I5F-A nrPDB 28 6.7 >1FSU-A nrPDB Length = 492 Score = 1020 bits (2637), Expect = 0.0, Method: Compositional matrix adjust. Identities = 491/492 (99%), Positives = 491/492 (99%) Query: 42 SRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTG 101 SRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQPL TPSRSQLLTG Sbjct: 1 SRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQPLATPSRSQLLTG 60 Query: 102 RYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRG 161 RYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRG Sbjct: 61 RYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRG 120 Query: 162 FDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIA 221 FDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIA Sbjct: 121 FDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIA 180 Query: 222 LITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVT 281 LITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVT Sbjct: 181 LITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVT 240 Query: 282 AALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKG 341 AALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKG Sbjct: 241 AALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKG 300 Query: 342 VKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVD 401 VKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVD Sbjct: 301 VKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVD 360 Query: 402 SSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSE 461 SSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSE Sbjct: 361 SSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSE 420 Query: 462 IPSSDPPTKTLWLFDIDRDPEERHDLSREYPHIVTKLLSRLQFYHKHSVPVYFPAQDPRC 521 IPSSDPPTKTLWLFDIDRDPEERHDLSREYPHIVTKLLSRLQFYHKHSVPVYFPAQDPRC Sbjct: 421 IPSSDPPTKTLWLFDIDRDPEERHDLSREYPHIVTKLLSRLQFYHKHSVPVYFPAQDPRC 480 Query: 522 DPKATGVWGPWM 533 DPKATGVWGPWM Sbjct: 481 DPKATGVWGPWM 492 >6BIA-A nrPDB Length = 477 Score = 211 bits (536), Expect = 7e-55, Method: Compositional matrix adjust. Identities = 150/486 (30%), Positives = 231/486 (47%), Gaps = 73/486 (15%) Query: 32 LAPPGSGAGASRPPHLVFLLADDLGWNDVGFHGSR-IRTPHLDALAAGGVLL-DNYYTQP 89 L P GS + + P+++ ++ADDLG+ DVGF+GS+ I TP++D LA G D Y P Sbjct: 14 LVPRGSHMASEQKPNIILIVADDLGYADVGFNGSKDIITPNIDDLAKSGTSFSDAYVAHP 73 Query: 90 LCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLG 149 C PSR+ L+TGRY + G Q + VP D K + +LL E Y T +GKWH+G Sbjct: 74 FCGPSRAALMTGRYPHKIGSQFNLPTRGSNVGVPTDAKFISKLLNENNYFTGALGKWHMG 133 Query: 150 MYRKECLPTRRGFDTYFGYLLGSEDY--------YSHERCTLIDALNVTRCALDFRDGEE 201 + P +RGFD Y+G+L G +Y Y ++ + + L+ +G+E Sbjct: 134 D-TPQHHPNKRGFDEYYGFLGGGHNYFPDQYQPQYKKQKAQGLKNIFEYITPLE-HNGKE 191 Query: 202 VATGYKNMYSTNIFTKRAIALITNHPPEK-PLFLYLALQSVHEPLQVPEEYLKPYDFIQD 260 V + Y T+ ++ A+ + +K P FLYLA + H PLQ +E + + I++ Sbjct: 192 VK---ETQYITDALSREAVNFVDKAVNKKHPFFLYLAYNAPHTPLQAKDEDMAMFPNIKN 248 Query: 261 KNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWS 320 K+R YAGMV +D VG + ALK + ++NT+ +F +DNGG+ G NN+PL+ K S Sbjct: 249 KDRKTYAGMVYAVDRGVGKLVEALKKNNQYDNTLIVFMSDNGGKLSKGANNFPLKAGKGS 308 Query: 321 LWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTI 380 EGG R P G + + D PT LA + LDG ++W Sbjct: 309 TQEGGFRVPMLFHWPKHVPAGKRFSHPVSALDLYPTFAALAGAKVEENQHLDGTNMW--- 365 Query: 381 SEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSVH--AAIRHGNW 438 P F+ + P KD+ P Y+ + + AAIR W Sbjct: 366 ----------------PAFIKNE-------NPHKDE---PIYALRHRKGYSDAAIRMNQW 399 Query: 439 KLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLW-LFDIDRDPEERHDLSREYPHIVTK 497 K L V++ P W LF+I+ D E+HD+S+ ++T Sbjct: 400 KALK----------------VNQQP---------WQLFNIENDISEKHDVSKSNKALLTD 434 Query: 498 LLSRLQ 503 ++ ++ Sbjct: 435 MVREME 440 >4FDJ-A nrPDB Length = 502 Score = 161 bits (407), Expect = 7e-40, Method: Compositional matrix adjust. Identities = 150/508 (29%), Positives = 230/508 (45%), Gaps = 88/508 (17%) Query: 41 ASRPPHLVFLLADDLGWNDVGFHGSRIR-TPHLDALAAGGVLLDNYYT-QPLCTPSRSQL 98 A +PP+++ LL DD+GW D+G +G R TP+LD +AA G+L N+Y+ PL +PSR+ L Sbjct: 1 APQPPNILLLLMDDMGWGDLGVYGEPSRETPNLDRMAAEGLLFPNFYSANPLXSPSRAAL 60 Query: 99 LTGRYQIRTGLQ------------HQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKW 146 LTGR IR G +I+ +P E+LLP+LLK+AGY + +VGKW Sbjct: 61 LTGRLPIRNGFYTTNAHARNAYTPQEIV-----GGIPDSEQLLPELLKKAGYVSKIVGKW 115 Query: 147 HLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALD-FRDGEEVA-- 203 HLG +R + P + GFD +FG C N R + +RD E V Sbjct: 116 HLG-HRPQFHPLKHGFDEWFG----------SPNCHFGPYDNKARPNIPVYRDWEMVGRY 164 Query: 204 ---------TGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKP 254 TG N+ T I+ + A+ I P FLY A+ + H P+ KP Sbjct: 165 YEEFPINLKTGEANL--TQIYLQEALDFIKRQARHHPFFLYWAVDATHAPVYAS----KP 218 Query: 255 YDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLA----GGN 310 F+ R Y V +D+++G + L+ + +NT F++DNG ++ GG+ Sbjct: 219 --FLGTSQRGRYGDAVREIDDSIGKILELLQDLHVADNTFVFFTSDNGAALISAPEQGGS 276 Query: 311 NWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKP 370 N P K + +EGG+R P G + +L I D T + LA + Sbjct: 277 NGPFLCGKQTTFEGGMREPALAWWPGHVTAGQVSHQLGSIMDLFTTSLALAGLTPPSDRA 336 Query: 371 LDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSVH 430 +DG ++ T+ +G R + D MA ++L ++ A H Sbjct: 337 IDGLNLLPTLLQGRLMDRPIFYYRGD-----------TLMA-----ATLGQHKA-----H 375 Query: 431 AAIRHGNWK-LLTGYPGCGYWFPPPSQYNVSEIPSS--DPPTKTLWLFDIDRDPEERHDL 487 +W+ G C P Q NVS + + + TK +F + RDP ER L Sbjct: 376 FWTWTNSWENFRQGIDFC------PGQ-NVSGVTTHNLEDHTKLPLIFHLGRDPGERFPL 428 Query: 488 ---SREYPHIVTKLLSRLQFYHKHSVPV 512 S EY ++++ S +Q + + VP Sbjct: 429 SFASAEYQEALSRITSVVQQHQEALVPA 456 >3ED4-A nrPDB Length = 502 Score = 149 bits (377), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 127/441 (28%), Positives = 197/441 (44%), Gaps = 70/441 (15%) Query: 39 AGASRPPHLVFLLADDLGWNDVGFHGSRI-RTPHLDALAAGGVLLDNYYT-QPLCTPSRS 96 A ++ P+LV ++ADDLG+ D+ +G +I +TP++D LA GV +YY PL +PSR+ Sbjct: 22 AAEAKQPNLVIIMADDLGYGDLATYGHQIVKTPNIDRLAQEGVKFTDYYAPAPLSSPSRA 81 Query: 97 QLLTGRYQIRTGLQHQIIWPCQPSCVPL--DEKLLPQLLKEAGYTTHMVGKWHLGMYRKE 154 LLTGR RTG++ W V L +E + LLK GY T M+GK HL + Sbjct: 82 GLLTGRMPFRTGIRS---WIPSGKDVALGRNELTIANLLKAQGYDTAMMGKLHLNA-GGD 137 Query: 155 CLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDF-----RDGEEVATGYKNM 209 + D F Y L + + + TL +A R + + R+G+ T + Sbjct: 138 RTDQPQAQDMGFDYSLANTAGFVTD-ATLDNAKERPRYGMVYPTGWLRNGQ--PTPRADK 194 Query: 210 YSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPY-DFIQDKNRHH--- 265 S + + + N KP FLY+A VH PL P++YL Y ++ + H Sbjct: 195 MSGEYVSSEVVNWLDNKKDSKPFFLYVAFTEVHSPLASPKKYLDMYSQYMSAYQKQHPDL 254 Query: 266 ---------------YAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQT----- 305 Y +S +D VG V +K+ G +NT+ IF++DNG T Sbjct: 255 FYGDWADKPWRGVGEYYANISYLDAQVGKVLDKIKAMGEEDNTIVIFTSDNGPVTREARK 314 Query: 306 -----LAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKL 360 LAG + LRGRK +LWEGG+R + +G+ + ++ DW+PTL K+ Sbjct: 315 VYELNLAGETD-GLRGRKDNLWEGGIRVPAIIKYGKHLPQGMVSDTPVYGLDWMPTLAKM 373 Query: 361 ARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLP 420 + DG + + + + L+ ID F D Sbjct: 374 MNFKLPTDRTFDGESLVPVLEQKALKREKPLIFGIDMPFQD------------------- 414 Query: 421 EYSAFNTSVHAAIRHGNWKLL 441 + + AIR G+WK++ Sbjct: 415 -----DPTDEWAIRDGDWKMI 430 >4CXU-A nrPDB Length = 536 Score = 142 bits (357), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 140/562 (24%), Positives = 222/562 (39%), Gaps = 141/562 (25%) Query: 42 SRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTG 101 S+ P+ + ++ADDLG++D+G G I TP+LDALA G+ L +++T +P+RS LLTG Sbjct: 2 SKRPNFLVIVADDLGFSDIGTFGGEIATPNLDALAIAGLRLTDFHTASAASPTRSMLLTG 61 Query: 102 --RYQIRTGLQHQIIWP---CQPSCVP-LDEKL--LPQLLKEAGYTTHMVGKWHLGMYRK 153 + G + + P +P L+E++ LP+LL+EAGY T M GKWHLG+ + Sbjct: 62 TDHHIAGIGTMAEALTPELEGKPGYEGHLNERVVALPELLREAGYQTLMAGKWHLGL-KP 120 Query: 154 ECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRC--ALDFRDGEEVATGYKNMYS 211 E P RGF+ F L G+ ++Y E + + AL D + T + YS Sbjct: 121 EQTPHARGFERSFALLPGAANHYGFEPPYDESTPRILKGTPALYVEDERYLDTLPEGFYS 180 Query: 212 TNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPY---------------- 255 ++ F + + + +P F YL + H PLQ P E ++ Y Sbjct: 181 SDAFGDKLLQYLKERDQSRPFFAYLPFSAPHWPLQAPREIVEKYRGRYDAGPEALRQERL 240 Query: 256 -------------------------DFIQDKNRHH-------YAGMVSLMDEAVGNVTAA 283 + ++D+ R YA MV MD +G V Sbjct: 241 ARLKELGLVEADVEAHPVLALTREWEALEDEERAKSARAMEVYAAMVERMDWNIGRVVDY 300 Query: 284 LKSSGLWNNTVFIFSTDNGG---------------------------QTLAGGNNWPLRG 316 L+ G +NT +F +DNG + + N++ G Sbjct: 301 LRRQGELDNTFVLFMSDNGAEGALLEAFPKFGPDLLDFLDRHYDNSLENIGRANSYVWYG 360 Query: 317 RKWS-------------LWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARG 363 +W+ +GG+R V P L ++G + + D PTL+ LA Sbjct: 361 PRWAQAATAPSRLYKAFTTQGGIRVPALVRYPRLSRQGAISHAFATVMDVTPTLLDLAGV 420 Query: 364 HTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYS 423 G + W+ P R L A D++++ + Sbjct: 421 RHPGKR-------WRGREIAEPRGRSWL------------GWLSGETEAAHDENTVTGWG 461 Query: 424 AFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEE 483 F AIR G+WK + + P P T L+D+ RDP E Sbjct: 462 LFGMR---AIRQGDWKAV--------YLPAPVG------------PATWQLYDLARDPGE 498 Query: 484 RHDLSREYPHIVTKLLSRLQFY 505 HDL+ P + +L+ + Y Sbjct: 499 IHDLADSQPGKLAELIEHWKRY 520 >1E2S-P nrPDB Length = 489 Score = 141 bits (356), Expect = 6e-34, Method: Compositional matrix adjust. Identities = 136/469 (28%), Positives = 199/469 (42%), Gaps = 70/469 (14%) Query: 43 RPPHLVFLLADDLGWNDVGFHGS-RIRTPHLDALAAGGVLLDNYYTQ-PLCTPSRSQLLT 100 RPP++V + ADDLG+ D+G +G TP+LD LAAGG+ ++Y L TPSR+ LLT Sbjct: 1 RPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLATPSRAALLT 60 Query: 101 GRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKEC-LPTR 159 GR +R G+ ++ P +PL+E + ++L GY T M GKWHLG+ + LP Sbjct: 61 GRLPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPH 120 Query: 160 RGFDTYFGYLLGSEDYYSHER--CTLIDAL-NVTRCALDFRDGEEVATGYKNMYSTNI-- 214 +GF + G YSH++ C + T C G N+ Sbjct: 121 QGFHRFLGI------PYSHDQGPCQNLTCFPPATPCDGGCDQGLVPIPLLANLSVEAQPP 174 Query: 215 ----FTKRAIALITN-----HPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHH 265 R +A + ++P FLY A H P F + R Sbjct: 175 WLPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYP------QFSGQSFAERSGRGP 228 Query: 266 YAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTL---AGGNNWPLRGRKWSLW 322 + + +D AVG + A+ GL T+ IF+ DNG +T+ GG + LR K + + Sbjct: 229 FGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSGLLRCGKGTTY 288 Query: 323 EGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISE 382 EGGVR P GV + EL D LPTL LA G LDGFD+ + Sbjct: 289 EGGVREPALAFWPGHIAPGVTH-ELASSLDLLPTLAALA-GAPLPNVTLDGFDLSPLLLG 346 Query: 383 GSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSVHA--AIRHGNWKL 440 SPR L Y ++ V A+R G +K Sbjct: 347 TGKSPRQSLFF----------------------------YPSYPDEVRGVFAVRTGKYKA 378 Query: 441 LTGYPGCGY--WFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEERHDL 487 G + P+ + S + + +PP L+D+ +DP E ++L Sbjct: 379 HFFTQGSAHSDTTADPACHASSSLTAHEPP----LLYDLSKDPGENYNL 423 >1P49-A nrPDB Length = 562 Score = 123 bits (309), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 147/584 (25%), Positives = 230/584 (39%), Gaps = 138/584 (23%) Query: 41 ASRPPHLVFLLADDLGWNDVGFHGSR-IRTPHLDALAAGGVLLDNYYT-QPLCTPSRSQL 98 A+ P+++ ++ADDLG D G +G++ IRTP++D LA+GGV L + PL TPSR+ Sbjct: 2 AASRPNIILVMADDLGIGDPGCYGNKTIRTPNIDRLASGGVKLTQHLAASPLATPSRAAF 61 Query: 99 LTGRYQIRTGLQH-----QIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGM--Y 151 +TGRY +R+G+ ++ +P DE +LLK+ GY+T ++GKWHLGM + Sbjct: 62 MTGRYPVRSGMASWSRTGVFLFTASSGGLPTDEITFAKLLKDQGYSTALIGKWHLGMSCH 121 Query: 152 RKECL---PTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYK- 207 K P GF+ ++G I N+ C +G TG+K Sbjct: 122 SKTDFCHHPLHHGFNYFYG----------------ISLTNLRDCKPG--EGSVFTTGFKR 163 Query: 208 ------NMYSTNIFTKRAI-ALITNHPPEKPLFLYLALQSV------------------- 241 + + T A+ L H P F L L ++ Sbjct: 164 LVFLPLQIVGVTLLTLAALNCLGLLHVPLGVFFSLLFLAALILTLFLGFLHYFRPLNCFM 223 Query: 242 ---HEPLQVPEEY--------LKPYDFIQDKNR----------HHYAGMVSLMDEA---- 276 +E +Q P Y ++ FIQ H + + S D A Sbjct: 224 MRNYEIIQQPMSYDNLTQRLTVEAAQFIQRNTETPFLLVLSYLHVHTALFSSKDFAGKSQ 283 Query: 277 --------------VGNVTAALKSSGLWNNTVFIFSTDNGGQT--------LAGGNNWPL 314 VG + L L N+T+ F++D G + GG+N Sbjct: 284 HGVYGDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGSNGIY 343 Query: 315 RGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGF 374 +G K + WEGG+R G + P + Q G K E D PT+ KLA + +DG Sbjct: 344 KGGKANNWEGGIRVPGILRWPRVIQAGQKIDEPTSNMDIFPTVAKLAGAPLPEDRIIDGR 403 Query: 375 DVWKTISEGSPSPRIELLHNIDPNFVDSSP-CPRNSMAPAKDDSSLPEYSAFNTSVHAAI 433 D+ + S E L + ++++ P+NS + K P ++ Sbjct: 404 DLMPLLEGKSQRSDHEFLFHYCNAYLNAVRWHPQNSTSIWKAFFFTPNFNP--------- 454 Query: 434 RHGNWKLLTGYPGCGYWFPPPSQYNV-SEIPSSDPPTKTLWLFDIDRDPEERHDL---SR 489 G GC F + S + DPP LFDI +DP ER+ L S Sbjct: 455 --------VGSNGC---FATHVCFCFGSYVTHHDPPL----LFDISKDPRERNPLTPASE 499 Query: 490 EYPHIVTKLLSRLQFYHKHSVPVYFPAQDPRCDPKATGVWGPWM 533 + + K++ H ++P + P +W PW+ Sbjct: 500 PRFYEILKVMQEAADRHTQTLP-----EVPDQFSWNNFLWKPWL 538 >2QZU-A nrPDB Length = 491 Score = 90.9 bits (224), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 101/410 (24%), Positives = 172/410 (41%), Gaps = 69/410 (16%) Query: 23 VLPLLLLLL-LAPPGSGAGASRP-PHLVFLLADDLGWNDVGFHGSR-IRTPHLDALAAGG 79 ++P LL + + G A +P P+LVF++AD + +G G ++TPHLD LA+ G Sbjct: 4 IIPQALLTMPILSTGLQAQEKQPTPNLVFIMADQYRGDAIGCIGKEPVKTPHLDKLASEG 63 Query: 80 VLLDNYYTQ-PLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDE--KLLPQLLKEA 136 + N + P+ +P+R L+TG Y I + + P V L + + +LK+ Sbjct: 64 INFTNAISSYPVSSPARGMLMTGMYPIGSKVTGNCNSETAPYGVELSQNARCWSDVLKDQ 123 Query: 137 GYTTHMVGKWHLGM----------------YRKECLPTRR-GFDTYFGYLLGSEDYYSHE 179 GY +GKWHL + + C P RR GFD + Y G+ DY+ Sbjct: 124 GYNMGYIGKWHLDAPYKPYVDTYNNRGKVAWNEWCPPERRHGFDHWIAY--GTYDYHLKP 181 Query: 180 RCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEK-PLFLYLAL 238 N T F Y N + +AI I +K P L +++ Sbjct: 182 M-----YWNTTAPRDSFY--------YVNQWGPEYEASKAIEYINGQKDQKQPFALVVSM 228 Query: 239 QSVHEPLQ-VPEEYLKPY-----------------------DFIQDKNRHHYAGMVSLMD 274 H + VP+ Y + Y D+ ++ R++YA ++ +D Sbjct: 229 NPPHTGYELVPDRYKEIYKDLDVEALCKGRPDIPAKGTEMGDYFRNNIRNYYA-CITGVD 287 Query: 275 EAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVAS 334 E VG + ALK + L++NT+ +F++D+G A N K +E +R ++ Sbjct: 288 ENVGRIIEALKQNNLFDNTIVVFTSDHGICMGAHEN-----AGKDIFYEESMRIPMILSW 342 Query: 335 PLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGS 384 P + + +I +D PTL+ + + + FD+ + G Sbjct: 343 PDQIKPRKSDPLMIAFADLYPTLLSMMGFSKEIPETVQTFDLSNEVLTGK 392 >5G2V-A nrPDB Length = 534 Score = 80.9 bits (198), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 59/204 (28%), Positives = 99/204 (48%), Gaps = 33/204 (16%) Query: 42 SRPPHLVFLLADDLGWNDVG-FHGSRIRTPHLDALAAGGVLLDN-YYTQPLCTPSRSQLL 99 ++ P+++F++ DD + + G+ I+TP++D +A G+ DN Y L PSR+ +L Sbjct: 26 TKRPNIIFMMTDDHTTQAMSCYGGNLIQTPNMDRIANEGIRFDNCYAVNALSGPSRACIL 85 Query: 100 TGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTR 159 TG++ G S D++ P+LL++AGY T M+GKWHL + Sbjct: 86 TGKFSHENGFTDN------ASTFNGDQQTFPKLLQQAGYQTAMIGKWHL-------ISEP 132 Query: 160 RGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDF-RDGEEVATGYKNMYSTNIFTKR 218 +GFD ++ L G HE+ D DF DG+ + + Y+T+I T + Sbjct: 133 QGFD-HWSILSG-----QHEQGDYYDP--------DFWEDGKHIV---EKGYATDIITDK 175 Query: 219 AIALITNHPPEKPLFLYLALQSVH 242 AI + N KP + ++ H Sbjct: 176 AINFLENRDKNKPFCMMYHQKAPH 199 >4UPI-A nrPDB Length = 576 Score = 67.4 bits (163), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 125/555 (22%), Positives = 209/555 (37%), Gaps = 129/555 (23%) Query: 34 PPGSGAGASRPPHLVFLLADDLGWNDVGFHG-SRIRTPHLDALAAGGVLLDNYYTQP-LC 91 P S ++ ++++++ D L ++ + +G R+ TP++D LA GV N Y Q + Sbjct: 18 PNSSSVPMTQNRNILWIMCDQLRFDYLSCYGHERLNTPNIDKLAKRGVRFTNAYVQATVA 77 Query: 92 TPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHL--- 148 PSR TGRY +R+ Q P + + E L L++ G ++GK H+ Sbjct: 78 GPSRMSAYTGRY-VRSHGSTQNGIPLR-----VGEPTLGDHLRDVGMRNVLIGKTHMRPD 131 Query: 149 --GMYRKECLPTRR--------GFDTY--------FGYLLGSEDYYSHERCTLIDALNVT 190 GM R P GFD + GY Y + R A N Sbjct: 132 LDGMKRLGIDPDSEIGARVGEGGFDAFDRDDGVHPTGYRKKEPAYNDYLRHAGFQAENPW 191 Query: 191 RCALDFRDGE--EVATGY------------KNMYSTNIFTKRAIALITNHPPE-KPLFLY 235 + +G+ E +G+ + T T+RA+ + + +P + Sbjct: 192 EFWANSAEGKGGENQSGWLLTHADKPARVPEEHSETAYMTRRAMEFMEAAEKDGRPWCAH 251 Query: 236 LALQSVHEPLQVPEEY--------LKP------------------------YDFIQDKNR 263 L+ H P VP Y +KP +F +D+ R Sbjct: 252 LSYIKPHWPYIVPAPYHDMFGPDDVKPAVRSDEELKAAHPLFKAMTEEVYSRNFARDEVR 311 Query: 264 HH----YAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKW 319 Y G++ +D+ +G + A ++ GL NT+ +F+ D+G G++W G K+ Sbjct: 312 EKVIPAYMGLIKQIDDQLGQLFAFMQERGLDENTMIVFTADHGDYL---GDHW--MGEKY 366 Query: 320 SLWEGGVRGVGFVASPLLKQ---KGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDV 376 +E + + P K +G + L+ + D PT V A G P+ Sbjct: 367 LFYEAAAKVPLIIYDPSDKADATRGTVSDALVEMIDLAPTFVDYA----GGVPPM----- 417 Query: 377 WKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHG 436 I EG + LLH+ D S R + D S+LP Sbjct: 418 --HILEGKSL--LPLLHD------DDSSWDRQYVFSELDYSNLP---------------A 452 Query: 437 NWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEERHDLSRE--YPHI 494 KL C +Y + E+ P LFD++ DP+E DL R+ + Sbjct: 453 RLKLGRDIQDCRATMVFDGRYKLVEVMGFAP-----ILFDLEVDPDELKDLGRDPSAEEV 507 Query: 495 VTKLLSRLQFYHKHS 509 +L S L +H+++ Sbjct: 508 RQRLTSALDAWHRNT 522 >6IOZ-A nrPDB Length = 517 Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 98/406 (24%), Positives = 154/406 (37%), Gaps = 89/406 (21%) Query: 46 HLVFLLADDLGWNDVGFHGSR-IRTPHLDALAAGGVLLDNYYTQ-PLCTPSRSQLLTGRY 103 +++ ++ DDL + +G +G + +R+P++D LA+ +L N + Q + PSR LTGR Sbjct: 5 NVLLIIVDDLRPS-LGCYGDKLVRSPNIDQLASHSLLFQNAFAQQAVAAPSRVSFLTGRR 63 Query: 104 QIRTGL-QHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGK-WHLGMYRKECLPTRRG 161 T L W +PQ KE GY T VGK +H G+ + Sbjct: 64 PDTTRLYDFNSYWRVHAGNF----STIPQYFKENGYVTMSVGKVFHPGISSNHTDDSPYS 119 Query: 162 FDTYFGYLLGSEDYYSHERCTLIDA-LNVT-RCALDFRDGEEVATGYKNMYSTNIFTKRA 219 + ++ Y SE Y + + C D L+ C +D D E K T++A Sbjct: 120 W-SFPPYHPSSEKYENTKTCRGPDGELHANLLCPVDVLDVPEGTLPDKQS------TEQA 172 Query: 220 IALITN-HPPEKPLFLYLALQSVHEPLQVPEEYLK------------------------- 253 I L+ P FL + H P + P+E+ K Sbjct: 173 IQLLEKMKTSASPFFLAVGYHKPHIPFRYPKEFQKLYPLENITLAPDPEVPDGLPPVAYN 232 Query: 254 -----------------------PYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLW 290 P DF Q K R Y VS +D VG + +AL L Sbjct: 233 PWMDIRQREDVQALNISVPYGPIPVDF-QRKIRQSYFASVSYLDTQVGRLLSALDDLQLA 291 Query: 291 NNTVFIFSTDNGGQTLAGGNNWP----------------LRGRKWSLWEGGVRGVGFV-- 332 N+T+ F++D+G L W + GR SL E G + ++ Sbjct: 292 NSTIIAFTSDHGW-ALGEHGEWAKYSNFDVATHVPLIFYVPGRTASLPEAGEKLFPYLDP 350 Query: 333 --ASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDV 376 ++ L + G ++ +L+ + PTL LA P+ F V Sbjct: 351 FDSASQLMEPGRQSMDLVELVSLFPTLAGLAGLQVPPRCPVPSFHV 396 >4MHX-A nrPDB Length = 510 Score = 66.2 bits (160), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 88/335 (26%), Positives = 132/335 (39%), Gaps = 92/335 (27%) Query: 20 LPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGG 79 +P LLL+L G +RP + + LLADD G+ ++ S I TPHLDALA Sbjct: 5 VPACCALLLVL-------GLCRARPRNALLLLADDGGFESGAYNNSAIATPHLDALARRS 57 Query: 80 VLLDNYYT-QPLCTPSRSQLLTGRYQIRTGLQ--HQIIWPCQPSCVPLDE-KLLPQLLKE 135 +L N +T +PSR+ LLTG Q + G+ HQ + D+ + LP LL + Sbjct: 58 LLFRNAFTSVSSSSPSRASLLTGLPQHQNGMYGLHQDVHHFN----SFDKVRSLPLLLSQ 113 Query: 136 AGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDA-LNVTRCAL 194 AG T ++GK H+G +T + + Y+ E +++ N+TR L Sbjct: 114 AGVRTGIIGKKHVGP------------ETVYPFDFA----YTEENGSVLQVGRNITRIKL 157 Query: 195 DFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVH------------ 242 R + ++P FLY+A H Sbjct: 158 LVRKFLQTQD------------------------DRPFFLYVAFHDPHRCGHSQPQYGTF 193 Query: 243 ----------------------EPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNV 280 +PL V Y P + V MD+ VG V Sbjct: 194 CEKFGNGESGMGRIPDWTPQAYDPLDVLVPYFVPNTPAARADLAAQYTTVGRMDQGVGLV 253 Query: 281 TAALKSSGLWNNTVFIFSTDNGGQTLAGGNN--WP 313 L+ +G+ N+T+ IF++DNG +G N WP Sbjct: 254 LQELRDAGVLNDTLVIFTSDNGIPFPSGRTNLYWP 288 >4UPL-A nrPDB Length = 569 Score = 57.4 bits (137), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 95/401 (23%), Positives = 149/401 (37%), Gaps = 98/401 (24%) Query: 46 HLVFLLADDLGWNDVGFHGSR-IRTPHLDALAAGGVLLDNYYTQ-PLCTPSRSQLLTGRY 103 +++F++ D L W+ + +G + + TPH+D LAA GV D Y Q P+C SR TGRY Sbjct: 19 NILFIMFDQLRWDYLSCYGHKTLNTPHIDRLAAKGVRFDRAYIQSPICGSSRMSTYTGRY 78 Query: 104 QIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHL-----GMYRKECLP- 157 H W P + + E + L+ AG +VGK H+ GM R P Sbjct: 79 V----HSHGASWNGIP--LKVGEMTMGDHLRAAGMGCWLVGKTHMRADEEGMARLGLEPD 132 Query: 158 -------TRRGFDTYF-----------GYL--LGSEDYYSHERCTLIDALN----VTRCA 193 GFD + GY G+++Y R ++ N Sbjct: 133 SLIGARVAECGFDVFERDDGMLPEGPDGYYDPDGAKEYNKFLRAKGYESDNPWHDFANSG 192 Query: 194 LDFRDGEEVATGY--KNMY----------STNIFTKRAIALITNHPPEKPLFLYLALQSV 241 LD D V +G+ KN T T RA+ I P +L+ Sbjct: 193 LD--DEGNVQSGWFLKNATRPANIAEEDSETPYLTSRAMEFIEQQT--GPWCCHLSYIKP 248 Query: 242 HEPLQVPEEYLKPY--DFIQD--------KNRH--------------------------H 265 H P VPE Y + + +QD +N H Sbjct: 249 HWPYIVPEPYASMFGPEHVQDVVRSDSERQNAHPLFKAFMDTKVGEAFSRQEVRDAVIPA 308 Query: 266 YAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGG 325 Y G++ D+ +G + L+ +G +T+ + ++D+G G++W G K + Sbjct: 309 YMGLIKQADDQMGRLFKWLEDTGRMQDTMIVLTSDHGDFL---GDHW--MGEKTFFHDAS 363 Query: 326 VRGVGFVASPLLKQKGVKNR---ELIHISDWLPTLVKLARG 363 R + P + + L+ D PT V+ A G Sbjct: 364 TRVPLIIYDPRPEADATRGSVCDALVESIDLAPTFVEAAGG 404 >2W8S-A nrPDB Length = 543 Score = 55.8 bits (133), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 49/167 (29%), Positives = 79/167 (47%), Gaps = 26/167 (15%) Query: 263 RHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLW 322 R Y G+++ +D+ +G V A L +G W++T+ IF++D+G Q G L Sbjct: 316 RATYCGLITEIDDCLGRVFAYLDETGQWDDTLIIFTSDHGEQL----------GDHHLLG 365 Query: 323 EGGVRGVGFVASPLLKQKGVKNRELIHIS-------DWLPTLVKLARGHTNGTKPLDGFD 375 + G F ++K G +NR I D +PT+++ G T + DG Sbjct: 366 KIGYNAESFRIPLVIKDAG-QNRHAGQIEEGFSESIDVMPTILEWLGGET--PRACDGRS 422 Query: 376 VWKTISEGSPSP-RIELLHNIDPN--FVDSSPCPRNSMAPAKDDSSL 419 + ++EG PS R EL + D F D P+NS+ ++DD SL Sbjct: 423 LLPFLAEGKPSDWRTELHYEFDFRDVFYDQ---PQNSVQLSQDDCSL 466 >4UPH-A nrPDB Length = 547 Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 81/335 (24%), Positives = 124/335 (37%), Gaps = 102/335 (30%) Query: 65 SRIRTPHLDALAAGGVLLDNYY--TQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCV 122 + ++TP++DALA GVL ++ T P +P+R+ L TG YQ + H++ C+ + Sbjct: 66 ASVKTPNVDALAQDGVLFTRHFAGTAP-ASPARATLYTGLYQ----MNHRV---CR-NGS 116 Query: 123 PLDEKL--LPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFD-------TYFGYLLGSE 173 PLD + L + GY + G + P RG D TY G L G Sbjct: 117 PLDARFDNLALAARRGGYDPTLFGY-------TDTAPDPRGMDPNDPHLTTYEGVLPGFS 169 Query: 174 DYY---SHERCTLIDALNVTRCALDFRD---------GE--EVATGY-KNMYSTNIFTKR 218 HE+ L + RD GE +VA Y K+ T Sbjct: 170 ARQLLPEHEKQWLSWLRSRGHPEATSRDIHIPVGATPGEISDVAPAYSKDETQTAFLAGE 229 Query: 219 AIALITNHPPEKPLFLYLALQSVHEPLQVPEEY---LKPYD---FIQDKNRHH------- 265 I + + P F +++ H P VPE Y P D F + NR Sbjct: 230 FIRWLGEQ--DAPWFAHVSFLRPHPPFSVPEPYNRMFTPSDGPAFARAANREAEQAVHPL 287 Query: 266 -----------------------------------YAGMVSLMDEAVGNVTAALKSSGLW 290 Y GM++ +D +G + ALK+ G W Sbjct: 288 LAFALPLIGKDSFIYGGEGSASDWTSEDLSAIRAIYYGMIAEVDTQLGRIWQALKNVGAW 347 Query: 291 NNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGG 325 ++T+ IF++D+ + G W L +GG Sbjct: 348 DDTLIIFTSDHA----------EMMGDHWMLGKGG 372 >2VQR-A nrPDB Length = 543 Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 96/429 (22%), Positives = 152/429 (35%), Gaps = 99/429 (23%) Query: 67 IRTPHLDALAAGGVLLDNYYTQPL-CTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLD 125 ++TP+LD L GV N+ T + P+R+ LLTG Y + H+ + + VPLD Sbjct: 61 LKTPNLDRLCREGVTFRNHVTTCVPAGPARASLLTGLYL----MNHRAVQ----NTVPLD 112 Query: 126 EKLLP--QLLKEAGYTTHMVGKWHLGMYRKECLPT----------RRGFDTYFGYLLGSE 173 ++ L + L+ GY ++G + P GF + E Sbjct: 113 QRHLNLGKALRGVGYDPALIGYTTTVPDPRTTSPNDPRFRVLGDLMDGFHPVGAFEPNME 172 Query: 174 DYYSHERCTLIDALNVTRCALDFRDGEEVATGY--------KNMYSTNIFTKRAIALITN 225 Y+ D L R + +GE+ G K + FT+RA+ + Sbjct: 173 GYFGWVAQNGFD-LPEHRPDIWLPEGEDAVAGATDRPSRIPKEFSDSTFFTERALTYLKG 231 Query: 226 HPPEKPLFLYLALQSVHEPLQVPEEY---LKPYD-------------------------- 256 KP FL+L H P Y +P D Sbjct: 232 RD-GKPFFLHLGYYRPHPPFVASAPYHAMYRPEDMPAPIRAANPDIEAAQHPLMKFYVDS 290 Query: 257 -----FIQDKN--------------RHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIF 297 F Q R Y G+++ +D+ +G V + L +G W++T+ IF Sbjct: 291 IRRGSFFQGAEGSGATLDEAELRQMRATYCGLITEVDDCLGRVFSYLDETGQWDDTLIIF 350 Query: 298 STDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRE------LIHIS 351 ++D+G Q G L + G F ++K G R Sbjct: 351 TSDHGEQL----------GDHHLLGKIGYNDPSFRIPLVIKDAGENARAGAIESGFTESI 400 Query: 352 DWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSP-RIELLHNIDPNFVDSSPCPRNSM 410 D +PT++ G DG + +SEG P R EL + D V S P++ + Sbjct: 401 DVMPTILDWLGGKI--PHACDGLSLLPFLSEGRPQDWRTELHYEYDFRDVYYSE-PQSFL 457 Query: 411 APAKDDSSL 419 +D SL Sbjct: 458 GLGMNDCSL 466 >3LXQ-A nrPDB Length = 450 Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 72/298 (24%), Positives = 111/298 (37%), Gaps = 53/298 (17%) Query: 25 PLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDN 84 P LL + + P + G + +LV LL + LG VG G TP+LD L G Sbjct: 68 PTLLPTMNSNPATYQGKRK--NLVILLQESLGAQFVGSLGGLPLTPNLDELMQEGW---- 121 Query: 85 YYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPS--CVPLDEK-----LLPQLLKEAG 137 +TQ T +RS + G + TG +P PS V L + + LLKE G Sbjct: 122 QFTQMYATGTRS--VRGIEAVTTG------FPPSPSRAVVKLSKSQTGFFTIADLLKEQG 173 Query: 138 YTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFR 197 Y T + + GFD +++ N T Sbjct: 174 YHTQFIYGGEANFDNMKTFFFGNGFDQ------------------IVEEKNYTNPGF--- 212 Query: 198 DGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDF 257 G + +++ K +KP F + S H P + PE ++ YD Sbjct: 213 ------VGSWGVSDEDLYNKADEEFERLSKGDKPFFSLVFTSSNHSPYEYPEGKIEQYD- 265 Query: 258 IQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLR 315 + R++ V D A+G K S W++T+FI D+ + G N P++ Sbjct: 266 SEHMTRNN---AVKYSDYALGTFFDKAKKSSYWDDTIFIVIADHDARVF-GANLVPVK 319 >4UOP-A nrPDB Length = 442 Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust. Identities = 55/267 (20%), Positives = 97/267 (36%), Gaps = 41/267 (15%) Query: 40 GASRPPHLVFLLADDLGWN--DVGFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQ 97 GA++ +L+ + + N +V +G I TP LD L + Y Q T S+S Sbjct: 53 GAAKGKNLIIVQLESFQRNLTNVKINGQSI-TPTLDGLQNETM----YSNQFFQTVSKSN 107 Query: 98 LLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLP 157 + + T + + +P+LL + Y T Y ++ Sbjct: 108 TADAEWSVYTSTFPSGYYTNTQTYGDRVIPSMPRLLGKNDYKTATFHTNDASFYNRDEFY 167 Query: 158 TRRGFDTYFG-YLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFT 216 GFD ++ G ED + F +EV ++ Sbjct: 168 PAVGFDKFYDRKFFGDED------------------VIGFSPSDEV-----------LYN 198 Query: 217 KRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLK---PYDFIQDKNRHHYAGMVSLM 273 K L + + + L S H P +P++ + P D ++D +Y V Sbjct: 199 KAFPILEEQYKNNQKFYAQLISVSSHMPFDIPKDKQEIDLPSD-LKDTELGNYFEAVHYA 257 Query: 274 DEAVGNVTAALKSSGLWNNTVFIFSTD 300 D+ +G LK SG+W+++V +F D Sbjct: 258 DKQLGEFIQKLKDSGIWDDSVVVFYGD 284 >4UPK-A nrPDB Length = 538 Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust. Identities = 32/113 (28%), Positives = 54/113 (47%), Gaps = 10/113 (8%) Query: 35 PGSGAGASRPPHLVFLLADDLGWNDV-GFHGSRIRTPHLDALAAGGVLLDNYY--TQPLC 91 PG + R +++F++ D L + + G + PHL ALA V +Y T P C Sbjct: 24 PGDPSSMGRQSNVLFIIIDQLRADCLWGALADHVELPHLRALAQDAVSFRRHYSVTNP-C 82 Query: 92 TPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVG 144 PSR+ +LTG+Y + H+ + P + D + +++AGY + G Sbjct: 83 GPSRASILTGQY----AMNHRSVRNGTP--LRHDTPNIATEMRKAGYLPLLFG 129 Score = 36.6 bits (83), Expect = 0.028, Method: Compositional matrix adjust. Identities = 18/61 (29%), Positives = 34/61 (55%), Gaps = 1/61 (1%) Query: 252 LKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNN 311 L+P D R Y G+ + +D +G V A LK +G +++T+ + + D+ G+ L ++ Sbjct: 299 LEPTDETIQTLRAVYLGLATEVDTHIGRVIAHLKETGQYDDTLIVVTADH-GEMLGDRHS 357 Query: 312 W 312 W Sbjct: 358 W 358 >4UG4-A nrPDB Length = 515 Score = 37.0 bits (84), Expect = 0.024, Method: Compositional matrix adjust. Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 7/83 (8%) Query: 67 IRTPHLDALAAGGVLLDNYYTQ-PLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLD 125 + P+L ALA N YT PLC P+R+ + G+ RT + S +P Sbjct: 32 LHAPNLKALAKRSARFHNNYTSSPLCAPARASFMAGQLPSRTRVYDNAA--EYQSSIP-- 87 Query: 126 EKLLPQLLKEAGYTTHMVGKWHL 148 L+ AGY T + GK H Sbjct: 88 --TYAHHLRRAGYYTALSGKMHF 108 Score = 33.9 bits (76), Expect = 0.20, Method: Compositional matrix adjust. Identities = 24/100 (24%), Positives = 45/100 (45%), Gaps = 12/100 (12%) Query: 236 LALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVF 295 + L ++ V EE ++ ++R Y +S +DE VG + L + + ++T+ Sbjct: 242 IMLSCDYQNFDVTEENVR-------RSRRAYFANISYLDEKVGELIDTLTRTRMLDDTLI 294 Query: 296 IFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASP 335 +F +D+ G L W K + +EG R +A P Sbjct: 295 LFCSDH-GDMLGERGLW----FKMNFFEGSARVPLMIAGP 329 >5FBY-A nrPDB Length = 563 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 36/144 (25%), Positives = 66/144 (45%), Gaps = 11/144 (7%) Query: 206 YKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKN-RH 264 +++++ST++ + + I + PP +P FL AL H P+ + + +I+ +N RH Sbjct: 381 FESLFSTHLHSPNSWTRIISRPPTEPEFLS-AL--THSPILLYFGHGSGAQYIRSRNIRH 437 Query: 265 --HYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLW 322 H V LM G +AAL + G + + +++ G G W + R + Sbjct: 438 LDHCRATVLLM----GCSSAALTAKGEFEPSGPVWNYMLAGAPAVVGTLWDVTDRDIDRF 493 Query: 323 EGGV-RGVGFVASPLLKQKGVKNR 345 GGV G G + + +K K + Sbjct: 494 AGGVLEGWGVLPEGCMGEKNGKKK 517 >5UDY-A nrPDB Length = 422 Score = 30.8 bits (68), Expect = 1.5, Method: Compositional matrix adjust. Identities = 25/88 (28%), Positives = 40/88 (45%), Gaps = 13/88 (14%) Query: 32 LAPPGSGAGASRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQP-- 89 LAP S ++ L+ + D WN + + TP+LDA+A GV Y P Sbjct: 10 LAPVQSQGSQNK---LLLVSFDGFRWN----YDQDVDTPNLDAMARDGV--KARYMTPAF 60 Query: 90 --LCTPSRSQLLTGRYQIRTGLQHQIIW 115 + +P L+TG+Y G+ H + + Sbjct: 61 VTMTSPCHFTLVTGKYIENHGVVHNMYY 88 >4KXA-A nrPDB Length = 888 Score = 30.0 bits (66), Expect = 2.7, Method: Compositional matrix adjust. Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 11/75 (14%) Query: 51 LADDLGWNDVGFHGSR-IRTPHL---------DALAAGGVLLDNYYTQPLCTPSRSQLLT 100 +AD LGWND G H ++ +R+ L +AL L + + + P +LL Sbjct: 652 IADSLGWNDAGDHVTKLLRSSVLGFACKMGDREALNNASSLFEQWLNGTVSLPVNLRLLV 711 Query: 101 GRYQIRTGLQHQIIW 115 RY ++ ++I W Sbjct: 712 YRYGMQNS-GNEISW 725 >5VEN-A nrPDB Length = 416 Score = 30.0 bits (66), Expect = 2.7, Method: Compositional matrix adjust. Identities = 12/35 (34%), Positives = 21/35 (60%) Query: 268 GMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNG 302 ++S +D +G + LK + LWNN I ++D+G Sbjct: 192 SVISDVDHKLGYLIKMLKRAKLWNNVNLIVTSDHG 226 >4UOO-A nrPDB Length = 459 Score = 30.0 bits (66), Expect = 2.7, Method: Compositional matrix adjust. Identities = 37/176 (21%), Positives = 70/176 (39%), Gaps = 36/176 (20%) Query: 132 LLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTR 191 +L + GYT+ + + + ++ + + G+D +F YY ++ +V+ Sbjct: 147 ILGQQGYTSAVFHGNYKSFWNRDEIYKQFGYDNFF-----DASYYD------MNEADVSN 195 Query: 192 CALD----FRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQV 247 L F++ EE + + + T T +TNH P P+ Sbjct: 196 YGLKDKPFFKESEEYLSSLQQPFYTKFIT------LTNHFPY--------------PIDE 235 Query: 248 PEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGG 303 + + P D + Y +DE+V + LK SGL++N+V I D+ G Sbjct: 236 KDASIAPAT-TGDSSVDTYFQTARYLDESVKSFVDYLKKSGLYDNSVIIMYGDHYG 290 >4PXL-B nrPDB Length = 517 Score = 30.0 bits (66), Expect = 2.9, Method: Compositional matrix adjust. Identities = 18/80 (22%), Positives = 36/80 (45%), Gaps = 5/80 (6%) Query: 234 LYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHY---AGMVSLMDEAVGNVTAALKSSGLW 290 + +A + P+ ++ + IQ N Y AG+V+ + V+ ++++ +W Sbjct: 409 MTIAQDEIFGPVMALMKFKTVEEVIQKANNTRYGLAAGIVTKNIDVANTVSRSIRAGAIW 468 Query: 291 NNTVFIFSTDN--GGQTLAG 308 N F F D GG ++G Sbjct: 469 INCYFAFDPDAPFGGYKMSG 488 >4LR2-A nrPDB Length = 401 Score = 29.3 bits (64), Expect = 4.1, Method: Compositional matrix adjust. Identities = 11/42 (26%), Positives = 26/42 (61%) Query: 261 KNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNG 302 +++ + + ++ +D+ +G++ LK GLW N I ++D+G Sbjct: 183 EDKENMSRVLKKIDDLIGDLVQRLKMLGLWENLNVIITSDHG 224 >4N31-A nrPDB Length = 163 Score = 29.3 bits (64), Expect = 5.1, Method: Composition-based stats. Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 4/78 (5%) Query: 215 FTKRAIALITNHPPEK--PLFLYLALQSVHEPLQVPE-EYLKPYDFIQDKNRHHYAGMVS 271 FT+ LI HPPEK P Y + P +VP Y D+ +++ Y G + Sbjct: 87 FTQEGGLLINGHPPEKEVPYLTYPHSSGPNFPYKVPTGTYFILNDYREERLDSRYYGALP 146 Query: 272 LMDEAVGNVTAALKSSGL 289 + ++ G ++ L+ G+ Sbjct: 147 I-NQIKGKISTLLRVRGI 163 >5I5F-A nrPDB Length = 586 Score = 28.5 bits (62), Expect = 6.7, Method: Compositional matrix adjust. Identities = 16/49 (32%), Positives = 25/49 (51%), Gaps = 4/49 (8%) Query: 258 IQDKNRHH----YAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNG 302 I D N+ + YA S +D + V AL+ +G ++NTV I + G Sbjct: 404 IDDSNQKNFVKRYASAASDVDAQINRVLNALREAGKFDNTVVIITAGRG 452 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1FSU-A nrPDB 675 0.0 1P49-A nrPDB 411 e-115 6BIA-A nrPDB 410 e-114 4FDJ-A nrPDB 391 e-109 4UPI-A nrPDB 362 e-100 1E2S-P nrPDB 355 2e-98 3ED4-A nrPDB 354 8e-98 4CXU-A nrPDB 353 1e-97 2QZU-A nrPDB 317 6e-87 4UPL-A nrPDB 290 1e-78 2VQR-A nrPDB 275 2e-74 6IOZ-A nrPDB 260 1e-69 2W8S-A nrPDB 259 3e-69 4UPH-A nrPDB 229 2e-60 3LXQ-A nrPDB 221 6e-58 4MHX-A nrPDB 214 8e-56 5G2V-A nrPDB 181 8e-46 Sequences not found previously or not previously below threshold: 4UPK-A nrPDB 170 2e-42 4UG4-A nrPDB 168 5e-42 5G2T-A nrPDB 128 7e-30 4UOP-A nrPDB 103 2e-22 2W8D-A nrPDB 74 2e-13 5I5F-A nrPDB 69 5e-12 5I5H-A nrPDB 69 6e-12 4UOO-A nrPDB 68 1e-11 2W5S-A nrPDB 68 1e-11 5UDY-A nrPDB 56 4e-08 4LR2-A nrPDB 46 3e-05 6G4G-A nrPDB 44 1e-04 5VEN-A nrPDB 43 2e-04 1O99-A nrPDB 43 3e-04 4QAX-A nrPDB 43 3e-04 4B56-A nrPDB 41 0.001 5VEM-A nrPDB 41 0.001 2W5W-A nrPDB 38 0.014 5MX9-A nrPDB 36 0.030 5XWI-A nrPDB 35 0.084 5JTL-E nrPDB 35 0.096 5YLE-A nrPDB 34 0.12 3WKX-A nrPDB 34 0.15 5FQ8-B nrPDB 34 0.19 5OLB-A nrPDB 33 0.32 6A83-A nrPDB 33 0.45 5MHP-A nrPDB 32 0.84 2MLZ-B nrPDB 31 1.2 4JSB-A nrPDB 31 1.2 4UDQ-A nrPDB 30 3.2 6M9Z-A nrPDB 28 9.9 >1FSU-A nrPDB Length = 492 Score = 675 bits (1742), Expect = 0.0, Method: Composition-based stats. Identities = 491/492 (99%), Positives = 491/492 (99%) Query: 42 SRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTG 101 SRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQPL TPSRSQLLTG Sbjct: 1 SRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQPLATPSRSQLLTG 60 Query: 102 RYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRG 161 RYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRG Sbjct: 61 RYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRG 120 Query: 162 FDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIA 221 FDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIA Sbjct: 121 FDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIA 180 Query: 222 LITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVT 281 LITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVT Sbjct: 181 LITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVT 240 Query: 282 AALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKG 341 AALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKG Sbjct: 241 AALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKG 300 Query: 342 VKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVD 401 VKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVD Sbjct: 301 VKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVD 360 Query: 402 SSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSE 461 SSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSE Sbjct: 361 SSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSE 420 Query: 462 IPSSDPPTKTLWLFDIDRDPEERHDLSREYPHIVTKLLSRLQFYHKHSVPVYFPAQDPRC 521 IPSSDPPTKTLWLFDIDRDPEERHDLSREYPHIVTKLLSRLQFYHKHSVPVYFPAQDPRC Sbjct: 421 IPSSDPPTKTLWLFDIDRDPEERHDLSREYPHIVTKLLSRLQFYHKHSVPVYFPAQDPRC 480 Query: 522 DPKATGVWGPWM 533 DPKATGVWGPWM Sbjct: 481 DPKATGVWGPWM 492 >1P49-A nrPDB Length = 562 Score = 411 bits (1057), Expect = e-115, Method: Composition-based stats. Identities = 143/584 (24%), Positives = 222/584 (38%), Gaps = 138/584 (23%) Query: 41 ASRPPHLVFLLADDLGWNDVGFHGSR-IRTPHLDALAAGGVLLDNYYTQ-PLCTPSRSQL 98 A+ P+++ ++ADDLG D G +G++ IRTP++D LA+GGV L + PL TPSR+ Sbjct: 2 AASRPNIILVMADDLGIGDPGCYGNKTIRTPNIDRLASGGVKLTQHLAASPLATPSRAAF 61 Query: 99 LTGRYQIRTGL-----QHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRK 153 +TGRY +R+G+ ++ +P DE +LLK+ GY+T ++GKWHLGM Sbjct: 62 MTGRYPVRSGMASWSRTGVFLFTASSGGLPTDEITFAKLLKDQGYSTALIGKWHLGMSCH 121 Query: 154 E-----CLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYK- 207 P GF+ ++G N+ C +G TG+K Sbjct: 122 SKTDFCHHPLHHGFNYFYGI----------------SLTNLRDCKPG--EGSVFTTGFKR 163 Query: 208 ------NMYSTNIFTKRAIALIT-NHPPEKPLFLYLALQS-------------------- 240 + + T A+ + H P F L L + Sbjct: 164 LVFLPLQIVGVTLLTLAALNCLGLLHVPLGVFFSLLFLAALILTLFLGFLHYFRPLNCFM 223 Query: 241 --VHEPLQVPEEY------------------------------------LKPYDFIQDKN 262 +E +Q P Y DF Sbjct: 224 MRNYEIIQQPMSYDNLTQRLTVEAAQFIQRNTETPFLLVLSYLHVHTALFSSKDFAGKSQ 283 Query: 263 RHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQT--------LAGGNNWPL 314 Y V MD +VG + L L N+T+ F++D G + GG+N Sbjct: 284 HGVYGDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGSNGIY 343 Query: 315 RGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGF 374 +G K + WEGG+R G + P + Q G K E D PT+ KLA + +DG Sbjct: 344 KGGKANNWEGGIRVPGILRWPRVIQAGQKIDEPTSNMDIFPTVAKLAGAPLPEDRIIDGR 403 Query: 375 DVWKTISEGSPSPRIELLHNIDPNFVDSSPC-PRNSMAPAKDDSSLPEYSAFNTSVHAAI 433 D+ + S E L + ++++ P+NS + K P ++ Sbjct: 404 DLMPLLEGKSQRSDHEFLFHYCNAYLNAVRWHPQNSTSIWKAFFFTPNFNP--------- 454 Query: 434 RHGNWKLLTGYPGCGYWFPPPSQYNV-SEIPSSDPPTKTLWLFDIDRDPEERHDL---SR 489 G GC F + S + DPP LFDI +DP ER+ L S Sbjct: 455 --------VGSNGC---FATHVCFCFGSYVTHHDPP----LLFDISKDPRERNPLTPASE 499 Query: 490 EYPHIVTKLLSRLQFYHKHSVPVYFPAQDPRCDPKATGVWGPWM 533 + + K++ H ++P + P +W PW+ Sbjct: 500 PRFYEILKVMQEAADRHTQTLP-----EVPDQFSWNNFLWKPWL 538 >6BIA-A nrPDB Length = 477 Score = 410 bits (1052), Expect = e-114, Method: Composition-based stats. Identities = 149/497 (29%), Positives = 234/497 (47%), Gaps = 72/497 (14%) Query: 32 LAPPGSGAGASRPPHLVFLLADDLGWNDVGFHGSR-IRTPHLDALAAGGVLLDNYY-TQP 89 L P GS + + P+++ ++ADDLG+ DVGF+GS+ I TP++D LA G + Y P Sbjct: 14 LVPRGSHMASEQKPNIILIVADDLGYADVGFNGSKDIITPNIDDLAKSGTSFSDAYVAHP 73 Query: 90 LCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLG 149 C PSR+ L+TGRY + G Q + VP D K + +LL E Y T +GKWH+G Sbjct: 74 FCGPSRAALMTGRYPHKIGSQFNLPTRGSNVGVPTDAKFISKLLNENNYFTGALGKWHMG 133 Query: 150 MYRKECLPTRRGFDTYFGYLLGSEDY--------YSHERCTLIDALNVTRCALDFRDGEE 201 + P +RGFD Y+G+L G +Y Y ++ + + L+ +G+E Sbjct: 134 -DTPQHHPNKRGFDEYYGFLGGGHNYFPDQYQPQYKKQKAQGLKNIFEYITPLE-HNGKE 191 Query: 202 VATGYKNMYSTNIFTKRAIALITNHPPEK-PLFLYLALQSVHEPLQVPEEYLKPYDFIQD 260 V + Y T+ ++ A+ + +K P FLYLA + H PLQ +E + + I++ Sbjct: 192 VK---ETQYITDALSREAVNFVDKAVNKKHPFFLYLAYNAPHTPLQAKDEDMAMFPNIKN 248 Query: 261 KNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWS 320 K+R YAGMV +D VG + ALK + ++NT+ +F +DNGG+ G NN+PL+ K S Sbjct: 249 KDRKTYAGMVYAVDRGVGKLVEALKKNNQYDNTLIVFMSDNGGKLSKGANNFPLKAGKGS 308 Query: 321 LWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTI 380 EGG R P G + + D PT LA + LDG ++W Sbjct: 309 TQEGGFRVPMLFHWPKHVPAGKRFSHPVSALDLYPTFAALAGAKVEENQHLDGTNMWP-- 366 Query: 381 SEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSVH--AAIRHGNW 438 F+ + P KD+ P Y+ + + AAIR W Sbjct: 367 -----------------AFIKNE-------NPHKDE---PIYALRHRKGYSDAAIRMNQW 399 Query: 439 KLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEERHDLSREYPHIVTKL 498 K L V++ P LF+I+ D E+HD+S+ ++T + Sbjct: 400 KALK----------------VNQQP--------WQLFNIENDISEKHDVSKSNKALLTDM 435 Query: 499 LSRLQFYH-KHSVPVYF 514 + ++ + + P +F Sbjct: 436 VREMEKWSWDNQQPSWF 452 >4FDJ-A nrPDB Length = 502 Score = 391 bits (1004), Expect = e-109, Method: Composition-based stats. Identities = 145/520 (27%), Positives = 221/520 (42%), Gaps = 77/520 (14%) Query: 41 ASRPPHLVFLLADDLGWNDVGFHGSRIR-TPHLDALAAGGVLLDNYY-TQPLCTPSRSQL 98 A +PP+++ LL DD+GW D+G +G R TP+LD +AA G+L N+Y PL +PSR+ L Sbjct: 1 APQPPNILLLLMDDMGWGDLGVYGEPSRETPNLDRMAAEGLLFPNFYSANPLXSPSRAAL 60 Query: 99 LTGRYQIRTGLQHQIIWPCQP-------SCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMY 151 LTGR IR G +P E+LLP+LLK+AGY + +VGKWHLG + Sbjct: 61 LTGRLPIRNGFYTTNAHARNAYTPQEIVGGIPDSEQLLPELLKKAGYVSKIVGKWHLG-H 119 Query: 152 RKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALD-FRDGEEVATGYKNMY 210 R + P + GFD +FG C N R + +RD E V Y+ Sbjct: 120 RPQFHPLKHGFDEWFG----------SPNCHFGPYDNKARPNIPVYRDWEMVGRYYEEFP 169 Query: 211 S---------TNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDK 261 T I+ + A+ I P FLY A+ + H P+ + F+ Sbjct: 170 INLKTGEANLTQIYLQEALDFIKRQARHHPFFLYWAVDATHAPVYASKP------FLGTS 223 Query: 262 NRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLA----GGNNWPLRGR 317 R Y V +D+++G + L+ + +NT F++DNG ++ GG+N P Sbjct: 224 QRGRYGDAVREIDDSIGKILELLQDLHVADNTFVFFTSDNGAALISAPEQGGSNGPFLCG 283 Query: 318 KWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVW 377 K + +EGG+R P G + +L I D T + LA + +DG ++ Sbjct: 284 KQTTFEGGMREPALAWWPGHVTAGQVSHQLGSIMDLFTTSLALAGLTPPSDRAIDGLNLL 343 Query: 378 KTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGN 437 T+ +G R + D +L + H + Sbjct: 344 PTLLQGRLMDRPIFYYRGD---------------------TLMAATLGQHKAHFWTWTNS 382 Query: 438 WK-LLTGYPGCGYWFPPPSQYNVSEIPSS--DPPTKTLWLFDIDRDPEERHDL---SREY 491 W+ G C P Q NVS + + + TK +F + RDP ER L S EY Sbjct: 383 WENFRQGIDFC------PGQ-NVSGVTTHNLEDHTKLPLIFHLGRDPGERFPLSFASAEY 435 Query: 492 PHIVTKLLSRLQFYHKHSVPVYFPAQDPRCDPKATGVWGP 531 ++++ S +Q + + VP A W P Sbjct: 436 QEALSRITSVVQQHQEALVPAQPQLNVCN---WAVMNWAP 472 >4UPI-A nrPDB Length = 576 Score = 362 bits (929), Expect = e-100, Method: Composition-based stats. Identities = 118/556 (21%), Positives = 203/556 (36%), Gaps = 129/556 (23%) Query: 33 APPGSGAGASRPPHLVFLLADDLGWNDVGFHGS-RIRTPHLDALAAGGVLLDNYYTQP-L 90 P S ++ ++++++ D L ++ + +G R+ TP++D LA GV N Y Q + Sbjct: 17 VPNSSSVPMTQNRNILWIMCDQLRFDYLSCYGHERLNTPNIDKLAKRGVRFTNAYVQATV 76 Query: 91 CTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHL-- 148 PSR TGRY +R+ Q P + + E L L++ G ++GK H+ Sbjct: 77 AGPSRMSAYTGRY-VRSHGSTQNGIPLR-----VGEPTLGDHLRDVGMRNVLIGKTHMRP 130 Query: 149 ---GMYRKECLPTRR--------GFDTY--------FGYLLGSEDYYSHERCTLIDALNV 189 GM R P GFD + GY Y + R A N Sbjct: 131 DLDGMKRLGIDPDSEIGARVGEGGFDAFDRDDGVHPTGYRKKEPAYNDYLRHAGFQAENP 190 Query: 190 TRCALDFRDGE--EVATGY------------KNMYSTNIFTKRAIALITNHPPE-KPLFL 234 + +G+ E +G+ + T T+RA+ + + +P Sbjct: 191 WEFWANSAEGKGGENQSGWLLTHADKPARVPEEHSETAYMTRRAMEFMEAAEKDGRPWCA 250 Query: 235 YLALQSVHEPLQVPEEYLKPY--------------------------------DFIQDKN 262 +L+ H P VP Y + +F +D+ Sbjct: 251 HLSYIKPHWPYIVPAPYHDMFGPDDVKPAVRSDEELKAAHPLFKAMTEEVYSRNFARDEV 310 Query: 263 RH----HYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRK 318 R Y G++ +D+ +G + A ++ GL NT+ +F+ D+G G++W G K Sbjct: 311 REKVIPAYMGLIKQIDDQLGQLFAFMQERGLDENTMIVFTADHGDYL---GDHW--MGEK 365 Query: 319 WSLWEGGVRGVGFVASPLLKQ---KGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFD 375 + +E + + P K +G + L+ + D PT V A G L+G Sbjct: 366 YLFYEAAAKVPLIIYDPSDKADATRGTVSDALVEMIDLAPTFVDYAGG-VPPMHILEGKS 424 Query: 376 VWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRH 435 + + + D S R + D S+LP Sbjct: 425 LLPLLHD------------------DDSSWDRQYVFSELDYSNLP--------------- 451 Query: 436 GNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEERHDLSRE--YPH 493 KL C +Y + E+ P LFD++ DP+E DL R+ Sbjct: 452 ARLKLGRDIQDCRATMVFDGRYKLVEVMGFAP-----ILFDLEVDPDELKDLGRDPSAEE 506 Query: 494 IVTKLLSRLQFYHKHS 509 + +L S L +H+++ Sbjct: 507 VRQRLTSALDAWHRNT 522 >1E2S-P nrPDB Length = 489 Score = 355 bits (911), Expect = 2e-98, Method: Composition-based stats. Identities = 131/466 (28%), Positives = 191/466 (40%), Gaps = 64/466 (13%) Query: 43 RPPHLVFLLADDLGWNDVGFHGS-RIRTPHLDALAAGGVLLDNYYTQ-PLCTPSRSQLLT 100 RPP++V + ADDLG+ D+G +G TP+LD LAAGG+ ++Y L TPSR+ LLT Sbjct: 1 RPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLATPSRAALLT 60 Query: 101 GRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECL-PTR 159 GR +R G+ ++ P +PL+E + ++L GY T M GKWHLG+ + P Sbjct: 61 GRLPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPH 120 Query: 160 RGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNI----- 214 +GF + G + L T C G N+ Sbjct: 121 QGFHRFLGI---PYSHDQGPCQNLTCFPPATPCDGGCDQGLVPIPLLANLSVEAQPPWLP 177 Query: 215 -FTKRAIALITN-----HPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAG 268 R +A + ++P FLY A H P F + R + Sbjct: 178 GLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYP------QFSGQSFAERSGRGPFGD 231 Query: 269 MVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTL---AGGNNWPLRGRKWSLWEGG 325 + +D AVG + A+ GL T+ IF+ DNG +T+ GG + LR K + +EGG Sbjct: 232 SLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSGLLRCGKGTTYEGG 291 Query: 326 VRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSP 385 VR P GV EL D LPTL LA LDGFD+ + Sbjct: 292 VREPALAFWPGHIAPGVT-HELASSLDLLPTLAALAGAPLP-NVTLDGFDLSPLLLGTGK 349 Query: 386 SPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSVH--AAIRHGNWKLLTG 443 SPR L Y ++ V A+R G +K Sbjct: 350 SPRQSLFF----------------------------YPSYPDEVRGVFAVRTGKYKAHFF 381 Query: 444 YPGCGY--WFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEERHDL 487 G + P+ + S + + +PP L+D+ +DP E ++L Sbjct: 382 TQGSAHSDTTADPACHASSSLTAHEPP----LLYDLSKDPGENYNL 423 >3ED4-A nrPDB Length = 502 Score = 354 bits (907), Expect = 8e-98, Method: Composition-based stats. Identities = 129/468 (27%), Positives = 202/468 (43%), Gaps = 66/468 (14%) Query: 20 LPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDVGFHGSRI-RTPHLDALAAG 78 L ++ L + A + A ++ P+LV ++ADDLG+ D+ +G +I +TP++D LA Sbjct: 3 LASLIGLAVCTGNAFSPALAAEAKQPNLVIIMADDLGYGDLATYGHQIVKTPNIDRLAQE 62 Query: 79 GVLLDNYYT-QPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPL--DEKLLPQLLKE 135 GV +YY PL +PSR+ LLTGR RTG++ W V L +E + LLK Sbjct: 63 GVKFTDYYAPAPLSSPSRAGLLTGRMPFRTGIRS---WIPSGKDVALGRNELTIANLLKA 119 Query: 136 AGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALD 195 GY T M+GK HL + + D F Y L + + + TL +A R + Sbjct: 120 QGYDTAMMGKLHLNAGG-DRTDQPQAQDMGFDYSLANTAGFVTD-ATLDNAKERPRYGMV 177 Query: 196 FRDG---EEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYL 252 + G T + S + + + N KP FLY+A VH PL P++YL Sbjct: 178 YPTGWLRNGQPTPRADKMSGEYVSSEVVNWLDNKKDSKPFFLYVAFTEVHSPLASPKKYL 237 Query: 253 KPY-DFIQDKNRHH------------------YAGMVSLMDEAVGNVTAALKSSGLWNNT 293 Y ++ + H Y +S +D VG V +K+ G +NT Sbjct: 238 DMYSQYMSAYQKQHPDLFYGDWADKPWRGVGEYYANISYLDAQVGKVLDKIKAMGEEDNT 297 Query: 294 VFIFSTDNGGQT----------LAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVK 343 + IF++DNG T LAG + LRGRK +LWEGG+R + +G+ Sbjct: 298 IVIFTSDNGPVTREARKVYELNLAGETDG-LRGRKDNLWEGGIRVPAIIKYGKHLPQGMV 356 Query: 344 NRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSS 403 + ++ DW+PTL K+ + DG + + + + L+ ID F D Sbjct: 357 SDTPVYGLDWMPTLAKMMNFKLPTDRTFDGESLVPVLEQKALKREKPLIFGIDMPFQD-- 414 Query: 404 PCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYPGCGYWF 451 + + AIR G+WK++ + Sbjct: 415 ----------------------DPTDEWAIRDGDWKMIIDRNNKPKYL 440 >4CXU-A nrPDB Length = 536 Score = 353 bits (905), Expect = 1e-97, Method: Composition-based stats. Identities = 139/563 (24%), Positives = 221/563 (39%), Gaps = 141/563 (25%) Query: 41 ASRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLT 100 S+ P+ + ++ADDLG++D+G G I TP+LDALA G+ L +++T +P+RS LLT Sbjct: 1 MSKRPNFLVIVADDLGFSDIGTFGGEIATPNLDALAIAGLRLTDFHTASAASPTRSMLLT 60 Query: 101 G--RYQIRTGLQHQIIWP---CQPSCVP-LDEKL--LPQLLKEAGYTTHMVGKWHLGMYR 152 G + G + + P +P L+E++ LP+LL+EAGY T M GKWHLG+ Sbjct: 61 GTDHHIAGIGTMAEALTPELEGKPGYEGHLNERVVALPELLREAGYQTLMAGKWHLGLKP 120 Query: 153 KECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTR--CALDFRDGEEVATGYKNMY 210 ++ P RGF+ F L G+ ++Y E + + AL D + T + Y Sbjct: 121 EQT-PHARGFERSFALLPGAANHYGFEPPYDESTPRILKGTPALYVEDERYLDTLPEGFY 179 Query: 211 STNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPY--------------- 255 S++ F + + + +P F YL + H PLQ P E ++ Y Sbjct: 180 SSDAFGDKLLQYLKERDQSRPFFAYLPFSAPHWPLQAPREIVEKYRGRYDAGPEALRQER 239 Query: 256 --------------------------DFIQDKNRHH-------YAGMVSLMDEAVGNVTA 282 + ++D+ R YA MV MD +G V Sbjct: 240 LARLKELGLVEADVEAHPVLALTREWEALEDEERAKSARAMEVYAAMVERMDWNIGRVVD 299 Query: 283 ALKSSGLWNNTVFIFSTDNGG---------------------------QTLAGGNNWPLR 315 L+ G +NT +F +DNG + + N++ Sbjct: 300 YLRRQGELDNTFVLFMSDNGAEGALLEAFPKFGPDLLDFLDRHYDNSLENIGRANSYVWY 359 Query: 316 GRKW-------------SLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLAR 362 G +W +GG+R V P L ++G + + D PTL+ LA Sbjct: 360 GPRWAQAATAPSRLYKAFTTQGGIRVPALVRYPRLSRQGAISHAFATVMDVTPTLLDLAG 419 Query: 363 GHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEY 422 G + W+ P R L A D++++ + Sbjct: 420 VRHPGKR-------WRGREIAEPRGRSWL------------GWLSGETEAAHDENTVTGW 460 Query: 423 SAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPE 482 F AIR G+WK + + P P T L+D+ RDP Sbjct: 461 GLFGMR---AIRQGDWKAV--------YLPAPVG------------PATWQLYDLARDPG 497 Query: 483 ERHDLSREYPHIVTKLLSRLQFY 505 E HDL+ P + +L+ + Y Sbjct: 498 EIHDLADSQPGKLAELIEHWKRY 520 >2QZU-A nrPDB Length = 491 Score = 317 bits (813), Expect = 6e-87, Method: Composition-based stats. Identities = 110/535 (20%), Positives = 199/535 (37%), Gaps = 114/535 (21%) Query: 23 VLPLLLLLL-LAPPGSGAGASRP-PHLVFLLADDLGWNDVGFHG-SRIRTPHLDALAAGG 79 ++P LL + + G A +P P+LVF++AD + +G G ++TPHLD LA+ G Sbjct: 4 IIPQALLTMPILSTGLQAQEKQPTPNLVFIMADQYRGDAIGCIGKEPVKTPHLDKLASEG 63 Query: 80 VLLDNYYTQ-PLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDE--KLLPQLLKEA 136 + N + P+ +P+R L+TG Y I + + P V L + + +LK+ Sbjct: 64 INFTNAISSYPVSSPARGMLMTGMYPIGSKVTGNCNSETAPYGVELSQNARCWSDVLKDQ 123 Query: 137 GYTTHMVGKWHLGM----------------YRKECLPTRR-GFDTYFGYLLGSEDYYSHE 179 GY +GKWHL + + C P RR GFD + Y G+ DY+ Sbjct: 124 GYNMGYIGKWHLDAPYKPYVDTYNNRGKVAWNEWCPPERRHGFDHWIAY--GTYDYHLKP 181 Query: 180 RCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEK-PLFLYLAL 238 N T F Y N + +AI I +K P L +++ Sbjct: 182 M-----YWNTTAPRDSFY--------YVNQWGPEYEASKAIEYINGQKDQKQPFALVVSM 228 Query: 239 QSVHEPLQ-VPEEYLKPY-----------------------DFIQDKNRHHYAGMVSLMD 274 H + VP+ Y + Y D+ ++ R+ Y ++ +D Sbjct: 229 NPPHTGYELVPDRYKEIYKDLDVEALCKGRPDIPAKGTEMGDYFRNNIRN-YYACITGVD 287 Query: 275 EAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVAS 334 E VG + ALK + L++NT+ +F++D+G A N K +E +R ++ Sbjct: 288 ENVGRIIEALKQNNLFDNTIVVFTSDHGICMGAHEN-----AGKDIFYEESMRIPMILSW 342 Query: 335 PLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHN 394 P + + +I +D PTL+ + + + FD+ + G + Sbjct: 343 PDQIKPRKSDPLMIAFADLYPTLLSMMGFSKEIPETVQTFDLSNEVLTGKNKKDL----- 397 Query: 395 IDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPP 454 + D+ + A+ + K+ Sbjct: 398 -----------VQPYYFVKFDNHATGYRGLRTDRYTYAVHATDGKI-------------- 432 Query: 455 SQYNVSEIPSSDPPTKTLWLFDIDRDPEERHDLSREYPHIVTKLLSRLQFYHKHS 509 + LFD DP E ++++ + + +L+ + + + Sbjct: 433 ---------------DNVILFDRTNDPHEMNNIASQQLKLTHTFNRQLKTWLEKT 472 >4UPL-A nrPDB Length = 569 Score = 290 bits (741), Expect = 1e-78, Method: Composition-based stats. Identities = 114/549 (20%), Positives = 186/549 (33%), Gaps = 142/549 (25%) Query: 46 HLVFLLADDLGWNDVGFHGSR-IRTPHLDALAAGGVLLDNYYTQ-PLCTPSRSQLLTGRY 103 +++F++ D L W+ + +G + + TPH+D LAA GV D Y Q P+C SR TGRY Sbjct: 19 NILFIMFDQLRWDYLSCYGHKTLNTPHIDRLAAKGVRFDRAYIQSPICGSSRMSTYTGRY 78 Query: 104 QIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHL-----GMYRKECLPT 158 H W P + + E + L+ AG +VGK H+ GM R P Sbjct: 79 VH----SHGASWNGIP--LKVGEMTMGDHLRAAGMGCWLVGKTHMRADEEGMARLGLEPD 132 Query: 159 --------RRGFDTYF-----------GYLL--GSEDYYSHERCTLIDALNVTR--CALD 195 GFD + GY G+++Y R ++ N Sbjct: 133 SLIGARVAECGFDVFERDDGMLPEGPDGYYDPDGAKEYNKFLRAKGYESDNPWHDFANSG 192 Query: 196 FRDGEEVATGY------------KNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHE 243 D V +G+ + T T RA+ I P +L+ H Sbjct: 193 LDDEGNVQSGWFLKNATRPANIAEEDSETPYLTSRAMEFIEQQT--GPWCCHLSYIKPHW 250 Query: 244 PLQVPEEYLKPY--DFIQDKNRH----------------------------------HYA 267 P VPE Y + + +QD R Y Sbjct: 251 PYIVPEPYASMFGPEHVQDVVRSDSERQNAHPLFKAFMDTKVGEAFSRQEVRDAVIPAYM 310 Query: 268 GMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVR 327 G++ D+ +G + L+ +G +T+ + ++D+G G++W G K + R Sbjct: 311 GLIKQADDQMGRLFKWLEDTGRMQDTMIVLTSDHGDFL---GDHW--MGEKTFFHDASTR 365 Query: 328 GVGFVASPLLKQ---KGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGS 384 + P + +G L+ D PT V+ A G L+G + + Sbjct: 366 VPLIIYDPRPEADATRGSVCDALVESIDLAPTFVEAAGGK-PAMHILEGESLIPILHGAR 424 Query: 385 PSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIR----HGNWKL 440 R+ + D S+ P + SV A+ NWKL Sbjct: 425 ------------------DHTLRDHVICEYDFSASPIAHLNDISVRQAVMFMVADKNWKL 466 Query: 441 LTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEERHDLSREYPH--IVTKL 498 + LFD+ DP+E DL + H ++ + Sbjct: 467 I-----------------------HFEADPRPMLFDLKNDPQELVDLGGDPAHADVIAGM 503 Query: 499 LSRLQFYHK 507 +L + + Sbjct: 504 YDKLFRWTR 512 >2VQR-A nrPDB Length = 543 Score = 275 bits (704), Expect = 2e-74, Method: Composition-based stats. Identities = 108/544 (19%), Positives = 178/544 (32%), Gaps = 144/544 (26%) Query: 33 APPGSGAG----ASRPPHLVFLLADDLGWNDVGFHGSR------IRTPHLDALAAGGVLL 82 P S + R +++ ++ D + V ++TP+LD L GV Sbjct: 17 VPNSSSVPGDPSSMRKKNVLLIVVDQWRADFVPHVLRADGKIDFLKTPNLDRLCREGVTF 76 Query: 83 DNYYTQPL-CTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLL--PQLLKEAGYT 139 N+ T + P+R+ LLTG Y + H+ + + VPLD++ L + L+ GY Sbjct: 77 RNHVTTCVPAGPARASLLTGLYL----MNHRAVQ----NTVPLDQRHLNLGKALRGVGYD 128 Query: 140 THMVGKWHLGMYRKECLPT----------RRGFDTYFGYLLGSEDYYSHERCTLIDALNV 189 ++G + P GF + E Y+ D L Sbjct: 129 PALIGYTTTVPDPRTTSPNDPRFRVLGDLMDGFHPVGAFEPNMEGYFGWVAQNGFD-LPE 187 Query: 190 TRCALDFRDGEEVATG--------YKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSV 241 R + +GE+ G K + FT+RA+ + KP FL+L Sbjct: 188 HRPDIWLPEGEDAVAGATDRPSRIPKEFSDSTFFTERALTYLKGRDG-KPFFLHLGYYRP 246 Query: 242 HEPLQVPEEYLKPY----------------------------------DFIQ-------- 259 H P Y Y F Q Sbjct: 247 HPPFVASAPYHAMYRPEDMPAPIRAANPDIEAAQHPLMKFYVDSIRRGSFFQGAEGSGAT 306 Query: 260 ------DKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWP 313 + R Y G+++ +D+ +G V + L +G W++T+ IF++D+G Q Sbjct: 307 LDEAELRQMRATYCGLITEVDDCLGRVFSYLDETGQWDDTLIIFTSDHGEQL-------- 358 Query: 314 LRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRE------LIHISDWLPTLVKLARGHTNG 367 G L + G F ++K G R D +PT++ G Sbjct: 359 --GDHHLLGKIGYNDPSFRIPLVIKDAGENARAGAIESGFTESIDVMPTILDWLGGKIP- 415 Query: 368 TKPLDGFDVWKTISEGSPSP-RIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFN 426 DG + +SEG P R EL + D V S P++ + +D SL Sbjct: 416 -HACDGLSLLPFLSEGRPQDWRTELHYEYDFRDVYYSE-PQSFLGLGMNDCSL------- 466 Query: 427 TSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEERHD 486 I+ +K + FD+ DP E + Sbjct: 467 ----CVIQDERYKYVHFA------------------------ALPPLFFDLRHDPNEFTN 498 Query: 487 LSRE 490 L+ + Sbjct: 499 LADD 502 >6IOZ-A nrPDB Length = 517 Score = 260 bits (663), Expect = 1e-69, Method: Composition-based stats. Identities = 109/521 (20%), Positives = 187/521 (35%), Gaps = 90/521 (17%) Query: 46 HLVFLLADDLGWNDVGFHGSR-IRTPHLDALAAGGVLLDNYYT-QPLCTPSRSQLLTGRY 103 +++ ++ DDL + +G +G + +R+P++D LA+ +L N + Q + PSR LTGR Sbjct: 5 NVLLIIVDDLRPS-LGCYGDKLVRSPNIDQLASHSLLFQNAFAQQAVAAPSRVSFLTGRR 63 Query: 104 QIRTGLQ-HQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGK-WHLGMYRKECLPTRRG 161 T L W +PQ KE GY T VGK +H G+ + Sbjct: 64 PDTTRLYDFNSYWRVHAGNF----STIPQYFKENGYVTMSVGKVFHPGISSNHTDDSPYS 119 Query: 162 FDTYFGYLLGSEDYYSHERCTLIDALNVTR--CALDFRDGEEVATGYKNMYSTNIFTKRA 219 + ++ Y SE Y + + C D C +D D E K T++A Sbjct: 120 W-SFPPYHPSSEKYENTKTCRGPDGELHANLLCPVDVLDVPEGTLPDKQS------TEQA 172 Query: 220 IALITN-HPPEKPLFLYLALQSVHEPLQVPEEYLKPYDF--------------------- 257 I L+ P FL + H P + P+E+ K Y Sbjct: 173 IQLLEKMKTSASPFFLAVGYHKPHIPFRYPKEFQKLYPLENITLAPDPEVPDGLPPVAYN 232 Query: 258 --------------------------IQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWN 291 Q K R Y VS +D VG + +AL L N Sbjct: 233 PWMDIRQREDVQALNISVPYGPIPVDFQRKIRQSYFASVSYLDTQVGRLLSALDDLQLAN 292 Query: 292 NTVFIFSTDNGGQTLAGG-----------NNWPL----RGRKWSLWEGGVRGVGFV---- 332 +T+ F++D+G G + PL GR SL E G + ++ Sbjct: 293 STIIAFTSDHGWALGEHGEWAKYSNFDVATHVPLIFYVPGRTASLPEAGEKLFPYLDPFD 352 Query: 333 ASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELL 392 ++ L + G ++ +L+ + PTL LA P+ F V + Sbjct: 353 SASQLMEPGRQSMDLVELVSLFPTLAGLAGLQVPPRCPVPSFHVELCREGKNLLKHFRFR 412 Query: 393 HNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFP 452 + ++ +P + + S +P++++ S+ G Y + Sbjct: 413 DLEEDPYLPGNPRELIAYSQYPRPSDIPQWNSDKPSLKDIKIMG-----YSIRTIDYRYT 467 Query: 453 PPSQYNVSEIPSSDPPTKTLWLFDIDRDPEERHDLSREYPH 493 +N E ++ L+ +D DP + H++ + Sbjct: 468 VWVGFNPDEFLANFSDIHAGELYFVDSDPLQDHNMYNDSQG 508 >2W8S-A nrPDB Length = 543 Score = 259 bits (661), Expect = 3e-69, Method: Composition-based stats. Identities = 100/476 (21%), Positives = 172/476 (36%), Gaps = 106/476 (22%) Query: 26 LLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDVGFH----GSR--IRTPHLDALAAGG 79 + + PG + +R +++ ++ D + + G ++TP+LD L G Sbjct: 15 TAVPNSSSVPGDPSSMTRK-NVLLIVVDQWRADFIPHLMRAEGREPFLKTPNLDRLCREG 73 Query: 80 VLLDNYYTQPL-CTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLL--PQLLKEA 136 + N+ T + P+R+ LLTG Y + H+ + + VPLD++ L + L+ Sbjct: 74 LTFRNHVTTCVPGGPARASLLTGLYL----MNHRAVQ----NTVPLDQRHLNLGKALRAI 125 Query: 137 GYTTHMVGKWHLGMYRKECL----------PTRRGFDTYFGYLLGSEDYYSHERCTLIDA 186 GY ++G + GF + + E Y+ + Sbjct: 126 GYDPALIGYTTTTPDPRTTSARDPRFTVLGDIMDGFRSVGAFEPNMEGYFGWVAQNGFE- 184 Query: 187 LNVTRCALDFRDGEEVATG--------YKNMYSTNIFTKRAIALITNHPPEKPLFLYLAL 238 L R + +GE G K + FT+RA+ + KP FL+L Sbjct: 185 LPENREDIWLPEGEHSVPGATDKPSRIPKEFSDSTFFTERALTYLKGRDG-KPFFLHLGY 243 Query: 239 QSVHEPLQVPEEYLKPY----------------------------DFIQ----------- 259 H P Y Y D I+ Sbjct: 244 YRPHPPFVASAPYHAMYKAEDMPAPIRAENPDAEAAQHPLMKHYIDHIRRGSFFHGAEGS 303 Query: 260 ---------DKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGN 310 + R Y G+++ +D+ +G V A L +G W++T+ IF++D+G Q Sbjct: 304 GATLDEGEIRQMRATYCGLITEIDDCLGRVFAYLDETGQWDDTLIIFTSDHGEQL----- 358 Query: 311 NWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRE------LIHISDWLPTLVKLARGH 364 G L + G F ++K G D +PT+++ G Sbjct: 359 -----GDHHLLGKIGYNAESFRIPLVIKDAGQNRHAGQIEEGFSESIDVMPTILEWLGGE 413 Query: 365 TNGTKPLDGFDVWKTISEGSPSP-RIELLHNIDPNFVDSSPCPRNSMAPAKDDSSL 419 T + DG + ++EG PS R EL + D V P+NS+ ++DD SL Sbjct: 414 TP--RACDGRSLLPFLAEGKPSDWRTELHYEFDFRDVFYDQ-PQNSVQLSQDDCSL 466 >4UPH-A nrPDB Length = 547 Score = 229 bits (584), Expect = 2e-60, Method: Composition-based stats. Identities = 94/528 (17%), Positives = 165/528 (31%), Gaps = 122/528 (23%) Query: 40 GASRPPHLVFLLADDLGWNDVGFHGS-RIRTPHLDALAAGGVLLDNYYT-QPLCTPSRSQ 97 + + P+++ + AD + + G ++TP++DALA GVL ++ +P+R+ Sbjct: 40 PSGKRPNVLLISADQWRGDCLSAVGHASVKTPNVDALAQDGVLFTRHFAGTAPASPARAT 99 Query: 98 LLTGRYQIRTGLQHQIIWPCQPSCVPLDEKL--LPQLLKEAGYTTHMVGKWHLGMYRKEC 155 L TG YQ + H++ + PLD + L + GY + G + Sbjct: 100 LYTGLYQ----MNHRVC----RNGSPLDARFDNLALAARRGGYDPTLFGYTDTAPDPRGM 151 Query: 156 LPTRRGFDTYFGYLLGSEDYY---SHERCTLIDALNVTRCALDFRD------------GE 200 P TY G L G HE+ L + RD + Sbjct: 152 DPNDPHLTTYEGVLPGFSARQLLPEHEKQWLSWLRSRGHPEATSRDIHIPVGATPGEISD 211 Query: 201 EVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYD---- 256 K+ T I + + P F +++ H P VPE Y + + Sbjct: 212 VAPAYSKDETQTAFLAGEFIRWLGEQ--DAPWFAHVSFLRPHPPFSVPEPYNRMFTPSDG 269 Query: 257 --FIQDKNRHH------------------------------------------YAGMVSL 272 F + NR Y GM++ Sbjct: 270 PAFARAANREAEQAVHPLLAFALPLIGKDSFIYGGEGSASDWTSEDLSAIRAIYYGMIAE 329 Query: 273 MDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFV 332 +D +G + ALK+ G W++T+ IF++D+ G++W L K ++G + Sbjct: 330 VDTQLGRIWQALKNVGAWDDTLIIFTSDHAEMM---GDHWML--GKGGFFDGSYHVPLVI 384 Query: 333 ASPLLK-QKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSP-RIE 390 P G + +D PTL LDG + + G P R Sbjct: 385 RDPGHPGGAGRQVERFTSAADIFPTLCDRLGLV--PDNHLDGGTLVPFLEGGEPEGWRDA 442 Query: 391 LLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYPGCGYW 450 D + R+ C Sbjct: 443 AFWEFDFRDIAKGEAERH-------------------------------FGLKSNACNLA 471 Query: 451 FPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEERHDLSREYPHIVTKL 498 ++ P L+D+ +DP E +++ + + +L Sbjct: 472 VIRDERFKYVHFAGLPP-----LLYDLAKDPMELTNVAADADYAAVRL 514 >3LXQ-A nrPDB Length = 450 Score = 221 bits (562), Expect = 6e-58, Method: Composition-based stats. Identities = 84/400 (21%), Positives = 139/400 (34%), Gaps = 66/400 (16%) Query: 25 PLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDN 84 P LL + + P + G + +LV LL + LG VG G TP+LD L G Sbjct: 68 PTLLPTMNSNPATYQGKRK--NLVILLQESLGAQFVGSLGGLPLTPNLDELMQEGWQFT- 124 Query: 85 YYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEK-----LLPQLLKEAGYT 139 Q T +RS + G + TG + V L + + LLKE GY Sbjct: 125 ---QMYATGTRS--VRGIEAVTTGFPPS----PSRAVVKLSKSQTGFFTIADLLKEQGYH 175 Query: 140 THMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDG 199 T + + GFD +++ N T Sbjct: 176 TQFIYGGEANFDNMKTFFFGNGFD------------------QIVEEKNYTNPGF----- 212 Query: 200 EEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQ 259 G + +++ K +KP F + S H P + PE ++ YD + Sbjct: 213 ----VGSWGVSDEDLYNKADEEFERLSKGDKPFFSLVFTSSNHSPYEYPEGKIEQYD-SE 267 Query: 260 DKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKW 319 R++ V D A+G K S W++T+FI D+ + G N P++ Sbjct: 268 HMTRNN---AVKYSDYALGTFFDKAKKSSYWDDTIFIVIADHDARVF-GANLVPVK---- 319 Query: 320 SLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKT 379 + Q K+ + + D PTL+ L + P+ G D+ K Sbjct: 320 -----HFHIPALII-GKDIQP-RKDDRIANNIDMPPTLLSLIG--VDAKTPMIGRDLTKP 370 Query: 380 ISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSL 419 ++ + D NF + ++P + S++ Sbjct: 371 LA----REDERAMMQYDKNFGYLTRDNLVVLSPGEKVSTM 406 >4MHX-A nrPDB Length = 510 Score = 214 bits (544), Expect = 8e-56, Method: Composition-based stats. Identities = 116/569 (20%), Positives = 190/569 (33%), Gaps = 131/569 (23%) Query: 20 LPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGG 79 +P LLL+L G +RP + + LLADD G+ ++ S I TPHLDALA Sbjct: 5 VPACCALLLVL-------GLCRARPRNALLLLADDGGFESGAYNNSAIATPHLDALARRS 57 Query: 80 VLLDNYYTQPLCTPSRSQ-LLTGRYQIRTGLQ--HQIIWPCQPSCVPLDEKLLPQLLKEA 136 +L N +T + LLTG Q + G+ HQ + + LP LL +A Sbjct: 58 LLFRNAFTSVSSSSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFD---KVRSLPLLLSQA 114 Query: 137 GYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLID-ALNVTRCALD 195 G T ++GK H+G +T + + Y+ E +++ N+TR L Sbjct: 115 GVRTGIIGKKHVGP------------ETVYPFDFA----YTEENGSVLQVGRNITRIKLL 158 Query: 196 FRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVH------------- 242 R + ++P FLY+A H Sbjct: 159 VRKFLQTQ------------------------DDRPFFLYVAFHDPHRCGHSQPQYGTFC 194 Query: 243 ---------------------EPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVT 281 +PL V Y P + V MD+ VG V Sbjct: 195 EKFGNGESGMGRIPDWTPQAYDPLDVLVPYFVPNTPAARADLAAQYTTVGRMDQGVGLVL 254 Query: 282 AALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLL-KQK 340 L+ +G+ N+T+ IF++DNG +G N G V+SP K+ Sbjct: 255 QELRDAGVLNDTLVIFTSDNGIPFPSGRTNLYWP---------GTAEPLLVSSPEHPKRW 305 Query: 341 GVKNRELIHISDWLPTLVKLARGHTNG-------TKPLDGFDVWKTISEGSPSPRIEL-- 391 G + + + D PT++ T L G + + E P Sbjct: 306 GQVSEAYVSLLDLTPTILDWFSIPYPSYAIFGSKTIHLTGRSLLPAL-EAEPLWATVFGS 364 Query: 392 --LHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYPGCGY 449 H + ++ S R+ + +P + + + + T Sbjct: 365 QSHHEVTMSYPMRSVQHRHFRLVHNLNFKMPF--PIDQDFYVSPTFQDLLNRTTAGQPTG 422 Query: 450 WFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEERHDLS-REYPHIVTKLLS-RLQFYHK 507 W+ L+D RDP E +L+ + ++L +L + Sbjct: 423 WYKD---------LRHYYYRARWELYDRSRDPHETQNLATDPRFAQLLEMLRDQLAKWQW 473 Query: 508 HSVPVYFPAQD--------PRCDPKATGV 528 + + A D P+C P + Sbjct: 474 ETHDPWVCAPDGVLEEKLSPQCQPLHNEL 502 >5G2V-A nrPDB Length = 534 Score = 181 bits (458), Expect = 8e-46, Method: Composition-based stats. Identities = 57/204 (27%), Positives = 97/204 (47%), Gaps = 31/204 (15%) Query: 41 ASRPPHLVFLLADDLGWNDVGFHG-SRIRTPHLDALAAGGVLLDN-YYTQPLCTPSRSQL 98 ++ P+++F++ DD + +G + I+TP++D +A G+ DN Y L PSR+ + Sbjct: 25 ETKRPNIIFMMTDDHTTQAMSCYGGNLIQTPNMDRIANEGIRFDNCYAVNALSGPSRACI 84 Query: 99 LTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPT 158 LTG++ G S D++ P+LL++AGY T M+GKWHL + Sbjct: 85 LTGKFSHENGFTDNA------STFNGDQQTFPKLLQQAGYQTAMIGKWHL-------ISE 131 Query: 159 RRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKR 218 +GFD + L G HE+ D + DG+ + + Y+T+I T + Sbjct: 132 PQGFDHW-SILSG-----QHEQGDYYDPDF-------WEDGKHIV---EKGYATDIITDK 175 Query: 219 AIALITNHPPEKPLFLYLALQSVH 242 AI + N KP + ++ H Sbjct: 176 AINFLENRDKNKPFCMMYHQKAPH 199 Score = 109 bits (271), Expect = 4e-24, Method: Composition-based stats. Identities = 68/436 (15%), Positives = 130/436 (29%), Gaps = 91/436 (20%) Query: 101 GRYQIRTGLQHQIIWPCQPSCVPL---DEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLP 157 G++ + G II + + ++ ++A + M HLG++ P Sbjct: 159 GKHIVEKGYATDIITDKAINFLENRDKNKPFCMMYHQKAPHRNWMPAPRHLGIFNNTIFP 218 Query: 158 TR-RGFDTYFGYLLGSEDYY---SHERCTLIDALNVTRCALDFRDGEEVATGYKNMYST- 212 FD Y G + + H D +TR + + + YK M S Sbjct: 219 EPANLFDDYEGRGKAAREQDMSIEHTLTNDWDLKLLTREEMLKDTTNRLYSVYKRMPSEV 278 Query: 213 -----NIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYA 267 + + +R K L Q +++D Y Sbjct: 279 QDKWDSAYAQRIAEYRKGDLKGKALIS--------WKYQ---------QYMRD-----YL 316 Query: 268 GMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVR 327 V +DE +G + L+ G +NT+ ++++D G G W K ++E R Sbjct: 317 ATVLAVDENIGRLLNYLEKIGELDNTIIVYTSDQGFFLGEHG--WF---DKRFMYEECQR 371 Query: 328 GVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSP 387 + P + G + + D+ PT + A + G + + +P Sbjct: 372 MPLIIRYPKAIKAGSTSSAISMNVDFAPTFLDFAGVEVPSD--IQGASLKPVLENEGKTP 429 Query: 388 RIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYPGC 447 + + + H IR ++KL+ Y Sbjct: 430 ADWRKAAYYHYYEYPAEH--------------------SVKRHYGIRTQDFKLIHFYND- 468 Query: 448 GYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEERHDL--SREYPHIVTKLLSRLQFY 505 ++D+ DP E +++ EY +L+ L+ Sbjct: 469 ---------------------IDEWEMYDMKADPREMNNIFGKAEYAKKQKELMQLLEET 507 Query: 506 HKHSVPVYFPAQDPRC 521 K + DP Sbjct: 508 QKQ-----YKDNDPDE 518 >4UPK-A nrPDB Length = 538 Score = 170 bits (429), Expect = 2e-42, Method: Composition-based stats. Identities = 81/434 (18%), Positives = 144/434 (33%), Gaps = 82/434 (18%) Query: 26 LLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDV-GFHGSRIRTPHLDALAAGGVLLDN 84 + + PG + R +++F++ D L + + G + PHL ALA V Sbjct: 15 TAVPNSSSVPGDPSSMGRQSNVLFIIIDQLRADCLWGALADHVELPHLRALAQDAVSFRR 74 Query: 85 YY--TQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHM 142 +Y T P C PSR+ +LTG+Y + H+ + P + D + +++AGY + Sbjct: 75 HYSVTNP-CGPSRASILTGQYA----MNHRSVRNGTP--LRHDTPNIATEMRKAGYLPLL 127 Query: 143 VGKWHLGMYR----------KECLPTRRGFDTYFGYLLG-SEDYYSHERCTLIDALNV-- 189 G K RGF L S + SH + + Sbjct: 128 FGYTDTSQDPRAYDANDPALKTYEFPMRGFHEVTEMRLEMSYPWQSHLKNRGYAFDDYAQ 187 Query: 190 ---TRCALDFRDGEEVATGY-KNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPL 245 R D Y T T + +A + + F +L H PL Sbjct: 188 VYVPRPDADGTPRLNGPAMYRAEDSDTAFLTDQFLANMPAWAGQN-WFAHLTYIRPHPPL 246 Query: 246 QVPEEYLKPYDFIQ---------------------------------------------- 259 P Y YD + Sbjct: 247 VAPAPYNTMYDPAKLPLPARLPGRDDETAEHPFFGPATRYSSPASFVLGFPDLEPTDETI 306 Query: 260 DKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKW 319 R Y G+ + +D +G V A LK +G +++T+ + + D+G + L ++W K Sbjct: 307 QTLRAVYLGLATEVDTHIGRVIAHLKETGQYDDTLIVVTADHG-EMLGDRHSW----GKM 361 Query: 320 SLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKT 379 ++++ + +P K G D +PT++ +DG + Sbjct: 362 TVYDAAYHTPLIIRAPGCK-PGHVVEAPTESIDLMPTILDWVGQEIPN--AVDGRSLRPF 418 Query: 380 ISEGSPSPRIELLH 393 ++ +PS + Sbjct: 419 LTGEAPSDWRQYSF 432 >4UG4-A nrPDB Length = 515 Score = 168 bits (425), Expect = 5e-42, Method: Composition-based stats. Identities = 88/491 (17%), Positives = 157/491 (31%), Gaps = 111/491 (22%) Query: 44 PPHLVFLLADDL-GWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQ-PLCTPSRSQLLTG 101 P+++ ++ D L G + P+L ALA N YT PLC P+R+ + G Sbjct: 8 KPNILIIMVDQLNGKLFPDGPADFLHAPNLKALAKRSARFHNNYTSSPLCAPARASFMAG 67 Query: 102 RYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWH-LGMYRKECLPTRR 160 + RT + L+ AGY T + GK H +G + R Sbjct: 68 QLPSRTRVYDNAAEYQS------SIPTYAHHLRRAGYYTALSGKMHFVGPDQLHGFEERL 121 Query: 161 GFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAI 220 D Y + DY + ID ++ E+ + + + Sbjct: 122 TTDIYPADFGWTPDY--RKPGERIDWWYHNLGSVTGAGVAEITNQMEYDDEVAFLANQKL 179 Query: 221 ALITNHPPE---KPLFLYLALQSVHEPLQVPEEYLKPYDFIQ------------------ 259 ++ + +P L ++ H+P ++ Y+ + Sbjct: 180 YQLSRENDDESRRPWCLTVSFTHPHDPYVARRKFWDLYEDCEHLTPEVGAIPLDEQDPHS 239 Query: 260 -------------------DKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTD 300 ++R Y +S +DE VG + L + + ++T+ +F +D Sbjct: 240 QRIMLSCDYQNFDVTEENVRRSRRAYFANISYLDEKVGELIDTLTRTRMLDDTLILFCSD 299 Query: 301 NGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKL 360 +G L W K + +EG R +A P G+ + D PTL L Sbjct: 300 HGD-MLGERGLWF----KMNFFEGSARVPLMIAGPG-IAPGL-HLTPTSNLDVTPTLADL 352 Query: 361 ARGHTNGTKP-LDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSL 419 A +P DG + ++ + + + + + ++ Sbjct: 353 AGISLEEVRPWTDGVSLVPMVNGVERTEPVLMEYAAEASYAPLV---------------- 396 Query: 420 PEYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDR 479 AIR G WK + Y P Q LFD++ Sbjct: 397 ------------AIREGKWKYV-------YCALDPEQ-----------------LFDLEA 420 Query: 480 DPEERHDLSRE 490 DP E +L+ Sbjct: 421 DPLELTNLAEN 431 >5G2T-A nrPDB Length = 489 Score = 128 bits (321), Expect = 7e-30, Method: Composition-based stats. Identities = 107/544 (19%), Positives = 169/544 (31%), Gaps = 147/544 (27%) Query: 35 PGSGAGASRPPHLVFLLADDLGWNDVGFHGS-RIRTPHLDALAAGGVLLDNYYTQ-PLCT 92 P G P+ + + D L VG +G + T +D +A+ GV+ N Y PL Sbjct: 14 PQQGLRQQEKPNFLIIQCDHLTQRVVGAYGQTQGCTLPIDEVASRGVIFSNAYVGCPLSQ 73 Query: 93 PSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYR 152 PSR+ L +G +T ++ P +P + L L E+GY GK H M Sbjct: 74 PSRAALWSGMMPHQTNVRSNSSEPVNTR-LPENVPTLGSLFSESGYEAVHFGKTH-DMGS 131 Query: 153 KECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYST 212 RGF A T + + G Sbjct: 132 L------RGFKHKEPV-----------------AKPFTDPEFPVNNDSFLDVGT------ 162 Query: 213 NIFTKRAIALITNHPPEKPLFLYLALQSVHE---------------PLQVPEEYL----- 252 + A+A ++N PP++P Q+ H P+ P L Sbjct: 163 ---CEDAVAYLSN-PPKEPFICIADFQNPHNICGFIGENAGVHTDRPISGPLPELPDNFD 218 Query: 253 --------KPYDFI--------------QDKNRH------HYAGMVSLMDEAVGNVTAAL 284 P +I ++ RH HY MVS V +V AL Sbjct: 219 VEDWSNIPTPVQYICCSHRRMTQAAHWNEENYRHYIAAFQHYTKMVSK---QVDSVLKAL 275 Query: 285 KSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKN 344 S+ NT+ + D+G + + + S ++ A P +KQ+ Sbjct: 276 YSTPAGRNTIVVIMADHGDGMASHR----MVTKHISFYDEMTNVPFIFAGPGIKQQKKPV 331 Query: 345 RELIH--ISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDS 402 L+ D LPTL LA K G + T+ + + + + Sbjct: 332 DHLLTQPTLDLLPTLCDLAGIAVPAEKA--GISLAPTLRGEKQKKSHPYVVSEWHSEYEY 389 Query: 403 SPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEI 462 P +R +K G G Sbjct: 390 VTTPGRM-----------------------VRGPRYKYTHYLEGNGEE------------ 414 Query: 463 PSSDPPTKTLWLFDIDRDPEERHDLSRE--YPHIVTKLLSRLQFYHKHSVPVYFPAQ--- 517 L+D+ +DP ER +L+++ Y I+ + + L Y S Y + Sbjct: 415 -----------LYDMKKDPGERKNLAKDPKYSKILAEHRALLDDYITRSKDDYRSLKVDA 463 Query: 518 DPRC 521 DPRC Sbjct: 464 DPRC 467 >4UOP-A nrPDB Length = 442 Score = 103 bits (256), Expect = 2e-22, Method: Composition-based stats. Identities = 70/433 (16%), Positives = 135/433 (31%), Gaps = 57/433 (13%) Query: 34 PPGSGAGASRPPHLVFLLADDLGWN--DVGFHGSRIRTPHLDALAAGGVLLDNYYTQPLC 91 GA++ +L+ + + N +V +G I TP LD L + N + Q + Sbjct: 47 SNPDYFGAAKGKNLIIVQLESFQRNLTNVKINGQSI-TPTLDGLQNE-TMYSNQFFQTVS 104 Query: 92 TPSRS----QLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWH 147 + + + T + +G +P+LL + Y T Sbjct: 105 KSNTADAEWSVYTSTFP--SGYYTNTQTYGDRVI-----PSMPRLLGKNDYKTATFHTND 157 Query: 148 LGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYK 207 Y ++ GFD ++ ++ E Sbjct: 158 ASFYNRDEFYPAVGFDKFYD-----RKFFGDEDVIGFSP--------------------- 191 Query: 208 NMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLK---PYDFIQDKNRH 264 ++ K L + + + L S H P +P++ + P D ++D Sbjct: 192 --SDEVLYNKAFPILEEQYKNNQKFYAQLISVSSHMPFDIPKDKQEIDLPSD-LKDTELG 248 Query: 265 HYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDN----GGQTLAGGNNWPLRGRK-W 319 +Y V D+ +G LK SG+W+++V +F D+ Q + R + Sbjct: 249 NYFEAVHYADKQLGEFIQKLKDSGIWDDSVVVFYGDHHIIKTDQLPEEQKKYVNRSTQLK 308 Query: 320 SLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKT 379 + R F+ P ++ G D +PT++ L T G + + G D+ + Sbjct: 309 AEPADDYRIPFFLHYPGMENPGEIKNVGGE-IDIMPTVMNLLGIKT-GDQIMFGTDILNS 366 Query: 380 ISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWK 439 + P + N P A + + + + + K Sbjct: 367 SNNYVPERYTMPEGSYFTNSYMYQPDESFETGAATNYDGTNKELSSDVKKRF---DASRK 423 Query: 440 LLTGYPGCGYWFP 452 LL P Sbjct: 424 LLQYSDSYVNNLP 436 >2W8D-A nrPDB Length = 436 Score = 73.7 bits (179), Expect = 2e-13, Method: Composition-based stats. Identities = 56/346 (16%), Positives = 111/346 (32%), Gaps = 53/346 (15%) Query: 33 APPGSGAGASRPPHLVFLLADDLGWNDVGF-HGSRIRTPHLDALA--AGGVLLDNYYTQP 89 P G + +++++ + L + + + TP L+ LA DN++ Q Sbjct: 20 VPNNVYFGKAEGKNVIYVSLESLQSFIIDYKIDGKEVTPFLNKLAHDNETFYFDNFFHQT 79 Query: 90 LCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDE-----KLLPQLLKEAGYTTHMVG 144 G+ + ++P V +++ + +P +LK YT+ Sbjct: 80 GQ---------GKTSDAEFMMENSLYPLAQGSVFVNKAQNTLQSVPAILKSKNYTSATFH 130 Query: 145 KWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVAT 204 + + + G D +F + D E T Sbjct: 131 GNTQTFWNRNEMYKAEGIDKFF--------------------------DSAYYDMNEENT 164 Query: 205 GYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLK-PYDFIQDKNR 263 M F K ++ L+ + P P + S H P + E P D Sbjct: 165 KNYGMKDKPFF-KESMPLLESLPQ--PFYTKFITLSNHFPFGMDEGDTDFPAGDFGDSVV 221 Query: 264 HHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWE 323 +Y +D+++ LK GL++ ++ + D+ G + K + + Sbjct: 222 DNYFQSAHYLDQSIEQFFNDLKKDGLYDKSIIVMYGDHYGISENHNKAMAKVLGKDEITD 281 Query: 324 GG----VRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHT 365 R F+ + +K G K + D PT++ L T Sbjct: 282 YDNAQLQRVPLFIHAAGVK--GEKVHKYAGDVDVAPTILHLLGVDT 325 >5I5F-A nrPDB Length = 586 Score = 68.7 bits (166), Expect = 5e-12, Method: Composition-based stats. Identities = 41/232 (17%), Positives = 70/232 (30%), Gaps = 37/232 (15%) Query: 162 FDTYFGYLLGSEDYYSHER--CTLIDALNV--TRCALDFRDG-----------EEVATGY 206 F ++G G D R LI ALN + L DG + + Sbjct: 307 FGLFYGISPGYMDGVLSTRTPAALITALNQQGYQLGLFSSDGFASPLYRQALLSDFSMPA 366 Query: 207 KNMYSTNIFTKRAIALITN-HPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHH 265 S + I + + F +++ D Q Sbjct: 367 AQTQSDAQTASQWIDWLGRYAQEDNRWFSWISFNGT-----------NIDDSNQKNFVKR 415 Query: 266 YAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGG 325 YA S +D + V AL+ +G ++NTV I + G N + Sbjct: 416 YASAASDVDAQINRVLNALREAGKFDNTVVIITAGRGIPLTPEENRFDWSQGH------- 468 Query: 326 VRGVGFVASPLLKQKGVKNRELIHISDWLPTLVK-LARGHTNGTKPLDGFDV 376 ++ + P + L +D + TL++ L T + G D+ Sbjct: 469 LQVPLVIHWPG--TPAQRINVLTDHTDVMTTLMQRLLHVSTPANEYSQGQDI 518 >5I5H-A nrPDB Length = 586 Score = 68.7 bits (166), Expect = 6e-12, Method: Composition-based stats. Identities = 26/181 (14%), Positives = 54/181 (29%), Gaps = 22/181 (12%) Query: 200 EEVATGYKNMYSTNIFTKRAIALITN-HPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFI 258 + + S + I + + F +++ D Sbjct: 360 SDFSMPSVRTQSDEQTATQWINWLGRYAQEDNRWFSWVSFNGT-----------NIDDSN 408 Query: 259 QDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRK 318 Q Y+ +D+ + V AL+ SG +NTV I + G + Sbjct: 409 QQAFARKYSRAAGNVDDQINRVLNALRDSGKLDNTVVIITAGRGIPLSEEEETFDWSHGH 468 Query: 319 WSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVK-LARGHTNGTKPLDGFDVW 377 ++ + P + L +D + TL++ L T ++ G D++ Sbjct: 469 -------LQVPLVIHWPG--TPAQRINALTDHTDLMTTLMQRLLHVSTPASEYSQGQDLF 519 Query: 378 K 378 Sbjct: 520 N 520 >4UOO-A nrPDB Length = 459 Score = 67.6 bits (163), Expect = 1e-11, Method: Composition-based stats. Identities = 50/331 (15%), Positives = 108/331 (32%), Gaps = 50/331 (15%) Query: 33 APPGSGAGASRPPHLVFLLADDLGWNDVGF--HGSRIRTPHLDALAAG--GVLLDNYYTQ 88 AP G ++ +++++ + V + +G + TP +++ + N++ Q Sbjct: 49 APNPEYFGKAKGKNVIYIHLESFQQFLVNYKLNGEEV-TPFINSFFKDQNTLSFTNFFHQ 107 Query: 89 PLCTP---SRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGK 145 S L Y GL + + + L + GYT+ + Sbjct: 108 TGQGKTADSEMLLENSLY----GLPQGSAFTTKGQNTYESASAI---LGQQGYTSAVFHG 160 Query: 146 WHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATG 205 + + ++ + + G+D +F + D E Sbjct: 161 NYKSFWNRDEIYKQFGYDNFF--------------------------DASYYDMNEADVS 194 Query: 206 YKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFI-QDKNRH 264 + F K + + ++P + + H P + E+ D + Sbjct: 195 NYGLKDKPFF-KESEEYL--SSLQQPFYTKFITLTNHFPYPIDEKDASIAPATTGDSSVD 251 Query: 265 HYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDN-GGQTLAGGNNWPLRGRKWSLWE 323 Y +DE+V + LK SGL++N+V I D+ G + G+ ++ +E Sbjct: 252 TYFQTARYLDESVKSFVDYLKKSGLYDNSVIIMYGDHYGISDNHEEAMTKILGKDYNTFE 311 Query: 324 G--GVRGVGFVASPLLKQKGVKNRELIHISD 352 R + P + +G + D Sbjct: 312 NAQAQRVPLMIHVPGV--QGGVQEQYGGQVD 340 >2W5S-A nrPDB Length = 424 Score = 67.6 bits (163), Expect = 1e-11, Method: Composition-based stats. Identities = 58/341 (17%), Positives = 113/341 (33%), Gaps = 50/341 (14%) Query: 34 PPGSGAGASRPPHLVFLLADDLGWNDVG--FHGSRIRTPHLDALAAGGVLLD---NYYTQ 88 P G ++ +++ + + + +G + TP L+ L++G N++ Q Sbjct: 19 PNPEYYGVAKKKNIIKIHLESFQTFLINKKVNGKEV-TPFLNKLSSGKEQFTYFPNFFHQ 77 Query: 89 PLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDE----KLLPQLL-KEAGYTTHMV 143 + T + + + Q S L + LP +L ++ GY + ++ Sbjct: 78 TGQGKTSDSEFT--------MDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVM 129 Query: 144 GKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVA 203 + + ++ + G D ++ YY D D V Sbjct: 130 HGDYKTFWNRDQVYKHFGIDKFYD-----ATYY------------------DMSDKNVVN 166 Query: 204 TGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPY-DFIQDKN 262 G K+ IF K + + P + +L + H P + E+ D Sbjct: 167 LGLKDK----IFFKDSANY--QAKMKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDAT 220 Query: 263 RHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLW 322 Y +DEA+ LK GL++N+V + D+ G + N + Sbjct: 221 VDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGISENHNNAMEKLLGEKITP 280 Query: 323 EGGVRGVGFVASPLLK-QKGVKNRELIHISDWLPTLVKLAR 362 + + G N E D +PT++ LA Sbjct: 281 AKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAG 321 >5UDY-A nrPDB Length = 422 Score = 56.0 bits (133), Expect = 4e-08, Method: Composition-based stats. Identities = 47/259 (18%), Positives = 81/259 (31%), Gaps = 46/259 (17%) Query: 47 LVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVL---LDNYYTQPLCTPSRSQLLTGRY 103 L+ + D WN + + TP+LDA+A GV + + +P L+TG+Y Sbjct: 22 LLLVSFDGFRWN----YDQDVDTPNLDAMARDGVKARYMTPAFVTM-TSPCHFTLVTGKY 76 Query: 104 QIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFD 163 G+ H + + + LP T + W G R+G Sbjct: 77 IENHGVVHNMYYNT------TSKVKLPYHA-----TLGIQRWWDNGSVPIWITAQRQGLR 125 Query: 164 TYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALI 223 + G Y A+ E +A YKN +A Sbjct: 126 AGSFFYPGGNVTYQGV-------------AVTRSRKEGIAHNYKNETEWRANIDTVMAWF 172 Query: 224 TNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAA 283 T + + L P + + MV +D VG + + Sbjct: 173 TEEDLD---LVTLYFGEP----DSTGHRYGPESPERRE-------MVRQVDRTVGYLRES 218 Query: 284 LKSSGLWNNTVFIFSTDNG 302 + + L + I ++D+G Sbjct: 219 IARNHLTDRLNLIITSDHG 237 >4LR2-A nrPDB Length = 401 Score = 46.4 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 40/272 (14%), Positives = 94/272 (34%), Gaps = 56/272 (20%) Query: 37 SGAGASRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQPLCT---P 93 S + +S PP L+ + D + + + PHL GVL++ + T P Sbjct: 3 SDSSSSLPPKLLLVSFDGFRADYLKNY----EFPHLQNFIKEGVLVE-HVKNVFITKTFP 57 Query: 94 SRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRK 153 + ++TG Y+ G+ ++ V K H Sbjct: 58 NHYSIVTGLYEESHGIVANSMYDA-------------------------VTKKHFSDSND 92 Query: 154 ECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTN 213 + ++ + ++ + + D + +++ + N S+ Sbjct: 93 K---DPFWWNEAVPIWVTNQLQENRSSAAAMW------PGTDVPIHDTISSYFMNYNSSV 143 Query: 214 IFTKRAIA---LITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMV 270 F +R + N P + +++ E + + +++ + + ++ Sbjct: 144 SFEERLNNITMWLNNSNPP------VTFATLYW----EEPDASGHKY-GPEDKENMSRVL 192 Query: 271 SLMDEAVGNVTAALKSSGLWNNTVFIFSTDNG 302 +D+ +G++ LK GLW N I ++D+G Sbjct: 193 KKIDDLIGDLVQRLKMLGLWENLNVIITSDHG 224 >6G4G-A nrPDB Length = 840 Score = 44.5 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 37/268 (13%), Positives = 81/268 (30%), Gaps = 59/268 (22%) Query: 43 RPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGV--LLDNYYTQPLCTPSRSQLLT 100 +PP ++F + D + + + P+++ L G+ P+ ++T Sbjct: 115 QPPVILFSM-DGFRAEYLQTWSTLL--PNINKLKTCGLHSKYMRAVYPTKTFPNHYTIVT 171 Query: 101 GRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRR 160 G Y G+ ++ + ++ V K + + + + Sbjct: 172 GLYPESHGIIDNNMY---------------DVYLNKNFSLSSVEKSNPAWWSGQPI---- 212 Query: 161 GFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKR-- 218 + + A + D Y+N ++ + R Sbjct: 213 ---------------WLTAMYQGLKAASYYWPGSDVAVNGSFPNIYRNYSNSVPYESRIA 257 Query: 219 -AIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSL---MD 274 + + E+P F + Y++ D K+ AG++ +D Sbjct: 258 TLLQWLDLPKAERPSFYTI--------------YVEEPDSAGHKSGPVSAGVIKALQLVD 303 Query: 275 EAVGNVTAALKSSGLWNNTVFIFSTDNG 302 +A G + LK L N I D+G Sbjct: 304 DAFGMLMEGLKQRNLHNCVNIIVLADHG 331 >5VEN-A nrPDB Length = 416 Score = 43.3 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 44/260 (16%), Positives = 78/260 (30%), Gaps = 53/260 (20%) Query: 47 LVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQPLCT---PSRSQLLTGRY 103 ++ + D W+ + ++ TPH + GV + N T T P+ L+TG + Sbjct: 16 VLVVSFDGFRWDYL----YKVPTPHFHYIMKNGVHV-NQVTNVFITKTYPNHYTLVTGLF 70 Query: 104 QIRTGLQHQIIW-PCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGF 162 G+ ++ P L+ + Y + + + G Sbjct: 71 AENHGIVANDMFDPILNKSFSLEHMDI--------YDSKFWEEATPIWITNQRAGHASGA 122 Query: 163 DTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIAL 222 + G + D + Y S + I Sbjct: 123 AMWPGADVKIHDSF-----------------------PTYYLPYNESVSFEDRVAKIIEW 159 Query: 223 ITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTA 282 T P FLY E +D D ++S +D +G + Sbjct: 160 FTAKDPINLGFLYWE-----------EPDDTGHDVGPDSPL--MGSVISDVDHKLGYLIK 206 Query: 283 ALKSSGLWNNTVFIFSTDNG 302 LK + LWNN I ++D+G Sbjct: 207 MLKRAKLWNNVNLIVTSDHG 226 >1O99-A nrPDB Length = 511 Score = 43.3 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 37/108 (34%), Gaps = 16/108 (14%) Query: 269 MVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRG 328 V +DE +G V A+ L + I + D+G + K Sbjct: 417 AVEAVDECLGKVVDAI----LAKGGIAIITADHG-----NADEVLTPDGKPQTAHTTNPV 467 Query: 329 VGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDV 376 V +KG+K R+ + D PT++ L K + G + Sbjct: 468 PVIV-----TKKGIKLRDGGILGDLAPTMLDLLG--LPQPKEMTGKSL 508 >4QAX-A nrPDB Length = 513 Score = 42.9 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 19/111 (17%), Positives = 35/111 (31%), Gaps = 16/111 (14%) Query: 269 MVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRG 328 + +DE +G V + + I + D+G ++ + Sbjct: 419 AIEAVDECLGEVVDKILDM----DGYAIITADHGNSDQVLTDDDQPMTTHTTNP-----V 469 Query: 329 VGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKT 379 V ++GV RE + D PTL+ L + G + K Sbjct: 470 PVIV-----TKEGVTLRETGRLGDLAPTLLDLLNVEQPED--MTGESLIKH 513 >4B56-A nrPDB Length = 820 Score = 41.4 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 42/273 (15%), Positives = 73/273 (26%), Gaps = 63/273 (23%) Query: 42 SRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQPLCT---PSRSQL 98 PP L+F L D + G + P + L G T P+ + Sbjct: 104 ESPPTLLFSL-DGFRAEYLHTWGGLL--PVISKLKNCG-TYTKNMRPMYPTKTFPNHYSI 159 Query: 99 LTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPT 158 +TG Y G+ + Y M + Sbjct: 160 VTGLYPESHGIIDNKM-----------------------YDPKM-----------NASFS 185 Query: 159 RRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKR 218 + + + + + + + D + YK + F +R Sbjct: 186 LKSKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEER 245 Query: 219 ---AIALITNHPPEKPLFLYLALQSV----HEPLQVPEEYLKPYDFIQDKNRHHYAGMVS 271 + + E+P F L L+ H V E +K + Sbjct: 246 ILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIK---------------ALQ 290 Query: 272 LMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQ 304 +D VG + LK GL I +D+G + Sbjct: 291 KVDRLVGMLMDGLKDLGLDKCLNLILISDHGME 323 >5VEM-A nrPDB Length = 416 Score = 41.0 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 37/260 (14%), Positives = 75/260 (28%), Gaps = 53/260 (20%) Query: 47 LVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGV---LLDNYYTQPLCTPSRSQLLTGRY 103 ++ + D W+ + ++ TPH + GV + N + P+ L+TG + Sbjct: 16 VLLVSFDGFRWDYL----YKVPTPHFHYIMKYGVHVKQVTNVFITK-TYPNHYTLVTGLF 70 Query: 104 QIRTGLQHQIIW-PCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGF 162 G+ ++ P + LD + Y + + + G Sbjct: 71 AENHGIVANDMFDPIRNKSFSLDHMNI--------YDSKFWEEATPIWITNQRAGHTSGA 122 Query: 163 DTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIAL 222 + G + + + + VA + S + Sbjct: 123 AMWPGTDVKIHKRF---------PTHYMPYNESVSFEDRVAKIIEWFTSKEPINLGLLYW 173 Query: 223 ITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTA 282 +L PL P +S +D+ +G + Sbjct: 174 EDPDDMGH----HLG---PDSPLMGPV--------------------ISDIDKKLGYLIQ 206 Query: 283 ALKSSGLWNNTVFIFSTDNG 302 LK + LWN I ++D+G Sbjct: 207 MLKKAKLWNTLNLIITSDHG 226 >2W5W-A nrPDB Length = 375 Score = 37.5 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 39/110 (35%), Gaps = 22/110 (20%) Query: 216 TKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGM-VSLMD 274 T AI + F+ D+ N Y ++ D Sbjct: 235 TDLAIQFL--SKDNSAFFIM--------------SEGSQIDWGGHANNASYLISEINDFD 278 Query: 275 EAVGNVTAALKSSGLWNNTVFIFSTDN--GGQTLAGGNNWPLRGRKWSLW 322 +A+G A K G NT+ I ++D+ GG TLA N G ++S + Sbjct: 279 DAIGTALAFAKKDG---NTLVIVTSDHETGGFTLAAKKNKREDGSEYSDY 325 >5MX9-A nrPDB Length = 324 Score = 36.4 bits (82), Expect = 0.030, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 33/98 (33%), Gaps = 3/98 (3%) Query: 264 HHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRG-RKWSLW 322 + Y + D+ + LK+ + ++ +D+G G N L G Sbjct: 213 NAYDNALLATDDFIAKSIDWLKTHEANYDVAMLYVSDHGESL--GENGVYLHGMPNAFAP 270 Query: 323 EGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKL 360 + F S K + ++ PTL+KL Sbjct: 271 KEQRAVPAFFWSNNTTFKPTASDTVLTHDAITPTLLKL 308 >5XWI-A nrPDB Length = 567 Score = 34.8 bits (78), Expect = 0.084, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 29/81 (35%), Gaps = 4/81 (4%) Query: 38 GAGASRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQPLCT---PS 94 A+ P +V + D + + + T L L + G + Y T P Sbjct: 34 SIAATPPKLIVAISVDQFSADLFSEY-RQYYTGGLKRLTSEGAVFPRGYQSHAATETCPG 92 Query: 95 RSQLLTGRYQIRTGLQHQIIW 115 S +LTG RTG+ + Sbjct: 93 HSTILTGSRPSRTGIIANNWF 113 Score = 33.7 bits (75), Expect = 0.21, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 16/35 (45%), Gaps = 2/35 (5%) Query: 270 VSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQ 304 V +D +G L G+ + V + + D+GG Sbjct: 317 VDRLDTELGAFFDKLDKDGI--DYVVVLTADHGGH 349 >5JTL-E nrPDB Length = 471 Score = 34.8 bits (78), Expect = 0.096, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 31/93 (33%), Gaps = 24/93 (25%) Query: 213 NIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSL 272 T +AI L+ EK FL QV + D + G + Sbjct: 322 AQMTDKAIELL--SKNEKGFFL-----------QVEGASIDKQDHAANP-----CGQIGE 363 Query: 273 ---MDEAVGNVTAALKSSGLWNNTVFIFSTDNG 302 +DEAV K G NT+ I + D+ Sbjct: 364 TVDLDEAVQRALEFAKKEG---NTLVIVTADHA 393 >5YLE-A nrPDB Length = 334 Score = 34.5 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 17/100 (17%), Positives = 33/100 (33%), Gaps = 6/100 (6%) Query: 264 HHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRG-RKWSLW 322 + Y + D+ + L++ + ++ +D+G G N L G Sbjct: 214 NAYDNALLATDDFIAQSIQWLQTHSNAYDVSMLYVSDHGESL--GENGVYLHGMPNAFAP 271 Query: 323 EGGVRGVGFVASPLL--KQKGVKNRELIHISDWLPTLVKL 360 + F + + L H + PTL+KL Sbjct: 272 KEQRSVPAFFWTDKQTGITPMATDTVLTHDA-ITPTLLKL 310 >3WKX-A nrPDB Length = 669 Score = 34.1 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 21/120 (17%), Positives = 40/120 (33%), Gaps = 10/120 (8%) Query: 54 DLGWNDVGFHGSRIRTPHLDALAAG-GVLLDNYYTQPLCTPSRSQLLTGRYQIR-----T 107 D+ D F+ +++ + D + G Y+ P R Q + +R T Sbjct: 222 DVRGQDPQFYAKQLKAMNGDNIFHDLGFYKPTYFQA--AEPVRDQQTADGHAVRVGYLCT 279 Query: 108 GLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFG 167 G+ H + ++ ++ Y T +G H+G DT +G Sbjct: 280 GVAHVGRLLGDQGLIDTAKRFWKNIVTRRMYVTGAIGSTHVGESFTYDYDLPN--DTMYG 337 >5FQ8-B nrPDB Length = 984 Score = 33.7 bits (75), Expect = 0.19, Method: Composition-based stats. Identities = 29/180 (16%), Positives = 51/180 (28%), Gaps = 29/180 (16%) Query: 163 DTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIAL 222 D+Y Y + + T +LN +F + + ++Y T R I++ Sbjct: 288 DSYDKYTFSARGSHKAGALTFSSSLNYAYQKNNFATTGQGLSMLNSLYQTP----RDISI 343 Query: 223 ITNHPPEKPLFLYLALQSV---HEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGN 279 I P + + P V Y +++ + + G +D Sbjct: 344 IGLEDQNDPF------NTPGYYYTPYGVMNPYYILNNYLNEYESERFYGKF-QLDYEFLK 396 Query: 280 VTAALKSSGLWNNTVFIFSTDNGGQTL------------AGGNNWPLRGRKWSLWEGGVR 327 GL T +D G L G++ P G E R Sbjct: 397 YFKFTYRMGLDTTTG---QSDKGKPNLYALYYEGTPNGEGQGSSSPFSGETGQYSEQITR 453 >5OLB-A nrPDB Length = 844 Score = 32.9 bits (73), Expect = 0.32, Method: Composition-based stats. Identities = 48/275 (17%), Positives = 86/275 (31%), Gaps = 71/275 (25%) Query: 35 PGSGAGASRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQPL---- 90 P AG RPP ++F + D + + GS++ P+++ L + G Y +P+ Sbjct: 123 PECPAGFVRPPLIIFSV-DGFRASYMK-KGSKVM-PNIEKLRSCGTHAP--YMRPVYPTK 177 Query: 91 CTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGM 150 P+ L TG Y G+ + Y +HL Sbjct: 178 TFPNLYTLATGLYPESHGIVGNSM-----------------------YDPVFDATFHL-- 212 Query: 151 YRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMY 210 RG + + + R L +T R G T + ++ Sbjct: 213 ---------RGREKF------------NHRWWGGQPLWITATKQGVRAG----TFFWSVS 247 Query: 211 ST-NIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGM 269 + ++ E+P A S + P+ Y + + Sbjct: 248 IPHERRILTILQWLSLPDNERP--SVYAFYS-----EQPDFSGHKYGPFGPEMTNP---- 296 Query: 270 VSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQ 304 + +D+ VG + LK L IF D+G + Sbjct: 297 LREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGME 331 >6A83-A nrPDB Length = 394 Score = 32.5 bits (72), Expect = 0.45, Method: Composition-based stats. Identities = 67/383 (17%), Positives = 125/383 (32%), Gaps = 64/383 (16%) Query: 9 LPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGAS---RPPHLVFLLADDLGWNDVGFHGS 65 +PRG R L + LL PP + P LV ++ + + +G Sbjct: 15 VPRGSHMYRQQLNSLTKLLNENNALPPLANFKDESGNEPRTLVLVIGESTQRGRMSLYGY 74 Query: 66 -RIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPL 124 R TP LDAL L + P Y I Q + + L Sbjct: 75 PRETTPELDALHKTDPNLTVFNNVVTSRP---------YTIEILQQALTFANEKNPDLYL 125 Query: 125 DEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLI 184 + L ++K+AGY T + ++ + R T F + Y + +R Sbjct: 126 TQPSLMNMMKQAGYKTFWI-------TNQQTMTARNTMLTVFSRQTDKQYYMNQQR---- 174 Query: 185 DALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEP 244 T Y TN+ K ++ + P+K + ++L + Sbjct: 175 -------------------TQSAREYDTNVL-KPFQEVLNDPAPKKLIIVHLLGTHIKYK 214 Query: 245 LQVPE---------EYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWN-NTV 294 + PE +++ P ++ ++ +L ++ V V + +K N N Sbjct: 215 YRYPENQGKFDGNTDHVPPGLNAEELESYNDYDNANLYNDHV--VASLIKDFKAANPNGF 272 Query: 295 FIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISD-- 352 ++ +D+G + + +GR + + F+ K + R+ D Sbjct: 273 LVYFSDHGEEVYDTPPH-KTQGRNEDNPTRHMYTIPFLLWTSEKWQATHPRDFSQDVDRK 331 Query: 353 -----WLPTLVKLARGHTNGTKP 370 + T LA +G P Sbjct: 332 YSLAELIHTWSDLAGLSYDGYDP 354 >5MHP-A nrPDB Length = 871 Score = 31.8 bits (70), Expect = 0.84, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 29/83 (34%), Gaps = 11/83 (13%) Query: 220 IALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGN 279 + +T E+P A S + P+ Y + + + +D+ VG Sbjct: 290 LQWLTLPDHERP--SVYAFYS-----EQPDFSGHKYGPFGPEMTNP----LREIDKIVGQ 338 Query: 280 VTAALKSSGLWNNTVFIFSTDNG 302 + LK L IF D+G Sbjct: 339 LMDGLKQLKLHRCVNVIFVGDHG 361 >2MLZ-B nrPDB Length = 114 Score = 31.0 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 16/39 (41%), Gaps = 3/39 (7%) Query: 264 HHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNG 302 H G +DEAV K G NT+ I + D+ Sbjct: 1 HMQIGETVDLDEAVQRALEFAKKEG---NTLVIVTADHA 36 >4JSB-A nrPDB Length = 296 Score = 31.0 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 16/53 (30%), Positives = 24/53 (45%), Gaps = 3/53 (5%) Query: 54 DLGWNDVGFHGSRIRTPHLDALAAGGVLLD---NYYTQPLCTPSRSQLLTGRY 103 DLG ++ F ++ + P + LAA G+ L L P R +TGR Sbjct: 12 DLGTENLYFQSAQTKAPTAEELAAAGLTLTIDGEVARITLSRPHRRNAMTGRM 64 >4UDQ-A nrPDB Length = 531 Score = 29.8 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 48/342 (14%), Positives = 94/342 (27%), Gaps = 54/342 (15%) Query: 151 YRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMY 210 Y + G+D + G L + ER + A G + + + Sbjct: 114 YDEWQALGADGWD-WQGVLP---YFIKTERDADYGDDPLHGNAGPIPIGRVDSRHWSDFT 169 Query: 211 STNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMV 270 A L H + Y P ++ + R ++ Sbjct: 170 VAATQALEAAGLPNIHDQNARF---------------DDGYFPPAFTLKGEER--FSAAR 212 Query: 271 SLMDEAVGNVTAALKSSGLWNNTVFI--FSTDN---GGQTLAGGNNWPLRGRKWSLWEGG 325 +D +V + LW + + +T N G L G ++ R+ L G Sbjct: 213 GYLDASV----RVRPNLSLWTESRVLKLLTTGNAITGVSVLRGRETLQVQAREVILTAGA 268 Query: 326 VRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSP 385 ++ + + + +P G ++W+ S G Sbjct: 269 LQSPAILLRTGIGPAAD---------------LHALGIPVLADRPGVGRNLWEHSSIGVV 313 Query: 386 SPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYP 445 +P E S A + D + P + ++G Sbjct: 314 APLTEQARADASTGKAGSRHQLGIRASSGVDPATPSDLFLHIGADP---------VSGLA 364 Query: 446 GCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEERHDL 487 +W PS ++ +DP + F++ DP + L Sbjct: 365 SAVFWVNKPSSTGWLKLKDADPFSYPDVDFNLLSDPRDLGRL 406 >6M9Z-A nrPDB Length = 230 Score = 28.3 bits (61), Expect = 9.9, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 17/57 (29%) Query: 147 HLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVA 203 HLG + LP G + + Y H D VT +G + Sbjct: 56 HLGYGFNQYLPFPDGMSPFQAAMQDESGYQVHRTLQYEDGAFVTANLRYTYEGSHIK 112 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.118 0.308 Lambda K H 0.267 0.0359 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,399,198 Number of Sequences: 36641 Number of extensions: 781132 Number of successful extensions: 2142 Number of sequences better than 10.0: 49 Number of HSP's better than 10.0 without gapping: 58 Number of HSP's successfully gapped in prelim test: 28 Number of HSP's that attempted gapping in prelim test: 1867 Number of HSP's gapped (non-prelim): 132 length of query: 533 length of database: 10,336,785 effective HSP length: 102 effective length of query: 431 effective length of database: 6,599,403 effective search space: 2844342693 effective search space used: 2844342693 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (28.3 bits)