BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P15693 (540 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4KJD-A nrPDB 1008 0.0 3MK1-A nrPDB 788 0.0 1SHQ-A nrPDB 369 e-102 3E2D-A nrPDB 137 2e-32 5JTL-E nrPDB 135 6e-32 3WBH-A nrPDB 125 6e-29 2W5W-A nrPDB 99 3e-21 3A52-A nrPDB 96 3e-20 2X98-A nrPDB 77 2e-14 2MLY-B nrPDB 47 2e-05 2DPN-A nrPDB 31 1.1 2MLZ-B nrPDB 31 1.4 5W16-A nrPDB 31 1.7 3S8M-A nrPDB 31 1.7 1JFX-A nrPDB 29 6.1 4Z2R-A nrPDB 28 7.4 >4KJD-A nrPDB Length = 488 Score = 1008 bits (2605), Expect = 0.0, Method: Compositional matrix adjust. Identities = 482/484 (99%), Positives = 483/484 (99%) Query: 21 VIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLG 80 VIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLG Sbjct: 1 VIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLG 60 Query: 81 GHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQ 140 GHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQ Sbjct: 61 GHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQ 120 Query: 141 CNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQ 200 CNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQ Sbjct: 121 CNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQ 180 Query: 201 EGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAK 260 EGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAK Sbjct: 181 EGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAK 240 Query: 261 YQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLS 320 YQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLS Sbjct: 241 YQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLS 300 Query: 321 RNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSH 380 RNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSH Sbjct: 301 RNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSH 360 Query: 381 VFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYK 440 VFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYK Sbjct: 361 VFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYK 420 Query: 441 QQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPA 500 QQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPA Sbjct: 421 QQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPA 480 Query: 501 DENR 504 DE+ Sbjct: 481 DEHH 484 >3MK1-A nrPDB Length = 484 Score = 788 bits (2035), Expect = 0.0, Method: Compositional matrix adjust. Identities = 367/480 (76%), Positives = 416/480 (86%) Query: 21 VIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLG 80 +IPVEEENP FWN++A EAL AKKLQP QT+AKNLI+FLGDGMGV TVTA RILKGQ Sbjct: 1 IIPVEEENPDFWNREAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKK 60 Query: 81 GHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQ 140 LGPE PLAMD FP+ ALSKTYNVD+ VPDS TATAYLCGVK N++TIG+SAAARFNQ Sbjct: 61 DKLGPEIPLAMDRFPYVALSKTYNVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQ 120 Query: 141 CNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQ 200 CN+T GNEV SVM+RAKKAGKSVGVVTTTRVQHASPAGTYAHTVNR+WYSDAD+P+SA Q Sbjct: 121 CNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADVPASARQ 180 Query: 201 EGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAK 260 EGC+DIATQLISNMDIDVILGGGRK+MF GTPDPEYP D Q G RLD +NLV+EWLAK Sbjct: 181 EGCQDIATQLISNMDIDVILGGGRKYMFRMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAK 240 Query: 261 YQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLS 320 QG RYVWNR +LMQAS DP+VT LMGLFEP +MKY+++R+++ DPSL EMTE A+RLLS Sbjct: 241 RQGARYVWNRTELMQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALRLLS 300 Query: 321 RNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSH 380 RNP+GF+LFVEGGRID GHH AY ALTE +MFD AIE+A QLT+E+DTL+L+TADHSH Sbjct: 301 RNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSH 360 Query: 381 VFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYK 440 VF+FGGY LRG+SIFGLAP A+D K+YT +LYGNGPGYVL G RP+VT++ESG Y+ Sbjct: 361 VFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYR 420 Query: 441 QQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPA 500 QQ+AVPL ETH GEDVA+FARGPQAHLVHGVQEQ +IAHVMAFA CLEPYT C LAPPA Sbjct: 421 QQSAVPLDEETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPPA 480 >1SHQ-A nrPDB Length = 478 Score = 369 bits (948), Expect = e-102, Method: Compositional matrix adjust. Identities = 203/476 (42%), Positives = 281/476 (59%), Gaps = 21/476 (4%) Query: 26 EENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGP 85 EE+ +WN+ A++ALD ++ + AKN+I FLGDGM + TVTA RI KG L G Sbjct: 1 EEDKAYWNKDAQDALDKQLGIKLREKQAKNVIFFLGDGMSLSTVTAARIYKGGLTGKFER 60 Query: 86 ETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTF 145 E ++ + F F ALSKTYN D+QV DSA +ATAYL GVK N IG+ A C+ Sbjct: 61 E-KISWEEFDFAALSKTYNTDKQVTDSAASATAYLTGVKTNQGVIGLDANTVRTNCSYQL 119 Query: 146 GNEVF--SVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQ-EG 202 +F S+ H ++AG+S GVVT+TRV HA+PAGTYAH +RDW +D+D+ E Sbjct: 120 DESLFTYSIAHWFQEAGRSTGVVTSTRVTHATPAGTYAHVADRDWENDSDVVHDREDPEI 179 Query: 203 CKDIATQLISN---MDIDVILGGGRKFMFPKGTPDPE--YPGDSDQSGVRLDSRNLVEEW 257 C DIA QL+ + VI+GGGR+ FP+ D E PG+ R D ++L+ +W Sbjct: 180 CDDIAEQLVFREPGKNFKVIMGGGRRGFFPEEALDIEDGIPGE------REDGKHLITDW 233 Query: 258 L--AKYQGT--RYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTE 313 L QG YVWNR+ L+ A LMGLF T + + R+A DP+L EMT+ Sbjct: 234 LDDKASQGATASYVWNRDDLL-AVDIRNTDYLMGLFSYTHLDTVLTRDAEMDPTLPEMTK 292 Query: 314 VAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTL 373 VA+ +L+++ GF+L VEGGRID HHA +L E + + A+ A +T+ ++T+ L Sbjct: 293 VAIEMLTKDENGFFLLVEGGRIDHMHHANQIRQSLAETLDMEEAVSMALSMTDPEETIIL 352 Query: 374 ITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGY-VLNSGNRPNVTDA 432 +TADH H GY R T I A ++ D + YT + YG+GPGY + G R T+ Sbjct: 353 VTADHGHTLTITGYADRNTDILDFAGISDLDDRRYTILDYGSGPGYHITEDGKRYEPTEE 412 Query: 433 ESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCL 488 + D+N++ +A P S TH G DV I+ GP AHL GV E+NYI H +A+A C+ Sbjct: 413 DLKDINFRYASAAPKHSVTHDGTDVGIWVNGPFAHLFTGVYEENYIPHALAYAACV 468 >3E2D-A nrPDB Length = 502 Score = 137 bits (344), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 112/347 (32%), Positives = 165/347 (47%), Gaps = 56/347 (16%) Query: 54 KNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTAL---SKTYNVDRQVP 110 KN+IL +GDGMG V Q + A+ + S T+ D V Sbjct: 4 KNVILMIGDGMGPQQVGLLETYANQAPNSIYKGNKTAIYQLAQEGVIGSSLTHPEDAIVV 63 Query: 111 DSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTR 170 DSA +AT G+ ++ + IG+ + GN V +V+ +AKKAGK+ G+V+ TR Sbjct: 64 DSACSATMLATGIYSSSEVIGIDSQ----------GNHVETVLEKAKKAGKATGLVSDTR 113 Query: 171 VQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNM---DIDVILGGGRKFM 227 + HA+PA AH +R + Q+ S+M DV+L GG + Sbjct: 114 LTHATPASFAAHQPHRS------------------LENQIASDMLATGADVMLSGGLRHW 155 Query: 228 FPKGTPDP--EYP-------GDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQ 278 PK T D Y GD R D RNL+ E A+ G + +NR L A Sbjct: 156 IPKSTNDKGETYKQLEKLTQGDVYLKSKRKDDRNLLTE--AEKDGYQLAFNRNMLDDAKG 213 Query: 279 DPAVTRLMGLFEPTEMKYDV---NRNASAD---PSLAEMTEVAVRLLSRNPQGFYLFVEG 332 D +L+GLF + M + N+ S + PSL EMT+ A+ +LS++ GF+L VEG Sbjct: 214 D----KLLGLFAYSGMDDGIAYSNKKKSGERTQPSLKEMTQKALNILSKDEDGFFLMVEG 269 Query: 333 GRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEK-DTLTLITADH 378 G+ID H+ A L E + FD AI+ + ++ DT+ ++TADH Sbjct: 270 GQIDWAGHSNDAGTMLHELLKFDEAIQTVYEWAKDREDTIVIVTADH 316 >5JTL-E nrPDB Length = 471 Score = 135 bits (339), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 144/506 (28%), Positives = 214/506 (42%), Gaps = 110/506 (21%) Query: 27 ENPVFWNQKAKEALDV---AKKLQPIQTSA----------KNLILFLGDGMGVPTVTATR 73 E PV N+ A+ + A++L QT+A KN+IL +GDGMG +TA R Sbjct: 25 EMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAAR 84 Query: 74 ILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQ------VPDSAGTATAYLCGVKANY 127 GG +D P T Y ++++ V DSA +ATA+ GVK Sbjct: 85 NYAEGAGGFFK-----GIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYN 139 Query: 128 KTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRD 187 +GV + + +++ AK AG + G V+T +Q A+PA AH +R Sbjct: 140 GALGVDIHEKDHP----------TILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRK 189 Query: 188 WY----SDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQ 243 Y + P +AL++G K T+ + N DV LGGG K F + E+ G Sbjct: 190 CYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAK-TFAETATAGEWQG---- 244 Query: 244 SGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEM--------- 294 + L E+ A+ +G + V + L ++ L+GLF M Sbjct: 245 -------KTLREQ--AQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKA 295 Query: 295 KYDVN-------------RNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHA 341 Y N RN S P+LA+MT+ A+ LLS+N +GF+L VEG ID+ HA Sbjct: 296 TYHGNIDKPAVTCTPNPQRNDSV-PTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHA 354 Query: 342 GTAYLALTEAVMFDSAIEKASQLT-NEKDTLTLITADHSHVFAFGGYTLRGTSIFGLA-P 399 + E V D A+++A + E +TL ++TADH+H T GL Sbjct: 355 ANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQI---VAPDTKAPGLTQA 411 Query: 400 LNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAI 459 LN +DG V++ GN S+ H G + I Sbjct: 412 LNTKDGAV-----------MVMSYGNSEE-------------------DSQEHTGSQLRI 441 Query: 460 FARGPQAHLVHGVQEQNYIAHVMAFA 485 A GP A V G+ +Q + + M A Sbjct: 442 AAYGPHAANVVGLTDQTDLFYTMKAA 467 >3WBH-A nrPDB Length = 527 Score = 125 bits (313), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 110/347 (31%), Positives = 161/347 (46%), Gaps = 47/347 (13%) Query: 54 KNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFP---FTALSKTYNVDRQVP 110 KN+IL +GDGMG V Q + P A S T+ D V Sbjct: 33 KNVILMIGDGMGPQQVGLLETYANQAPDSIYDGEPTAFHQLAKEGVVGFSLTHPEDAVVV 92 Query: 111 DSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTR 170 DSA +AT G+ + + IG+ A GN V +V+ A+ GK+ G+V+ TR Sbjct: 93 DSACSATQLASGIYSGSEVIGIDAE----------GNPVETVLELAQARGKATGLVSDTR 142 Query: 171 VQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPK 230 + HA+PA AH P +L+ +IA ++ + DV+L GG + P+ Sbjct: 143 LTHATPAAFAAH-----------QPHRSLE---NEIAVDML-EVGPDVMLSGGLRHWVPQ 187 Query: 231 -GTPDPE----YPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRL 285 + D E G + + R D RNL+ E + K G ++REQL D +L Sbjct: 188 SASEDAEVTSLMDGAYEPASKRQDDRNLLAEAVEK--GYGLAFSREQLEADQSD----KL 241 Query: 286 MGLFEPTEMKYDVN-RNASAD-----PSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGH 339 +GLF + M + RN D P+L EMT+ A+ L ++ GF+L VEGG+ID Sbjct: 242 LGLFANSGMADGIEYRNTRDDADRREPTLHEMTQAALNRLEQDEDGFFLMVEGGQIDWAG 301 Query: 340 HAGTAYLALTEAVMFDSAIEKASQLTN-EKDTLTLITADHSHVFAFG 385 H+ A L E V F+ A++ +DT+ L+TADH AFG Sbjct: 302 HSNDAGTMLNEMVKFEEAVQGVYDWAKGREDTVILVTADHE-TGAFG 347 >2W5W-A nrPDB Length = 375 Score = 99.4 bits (246), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 117/437 (26%), Positives = 176/437 (40%), Gaps = 98/437 (22%) Query: 45 KLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYN 104 K +P + KN+IL + DG G+ +++T K TP F L KT + Sbjct: 26 KNEPQLKTPKNVILLISDGAGLSQISSTFYFKSG--------TP-NYTQFKNIGLIKTSS 76 Query: 105 VDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVG 164 V DSA ATA+ CG+K IGV+ +ST V S++ A G Sbjct: 77 SREDVTDSASGATAFSCGIKTYNAAIGVAD-------DST---AVKSIVEIAALNNIKTG 126 Query: 165 VVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGR 224 VV T+ + A+PA YAH +NR L+E +IA + + D+D GGG Sbjct: 127 VVATSSITDATPASFYAHALNR-----------GLEE---EIAMDM-TESDLDFFAGGGL 171 Query: 225 KFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTR 284 + F K R D +++ LA +G ++ N L S A R Sbjct: 172 NY-FTK----------------RKDKKDV----LAILKGNQFTINTTALTDFSS-IASNR 209 Query: 285 LMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTA 344 MG E + + L+ T++A++ LS++ F++ EG +ID G HA A Sbjct: 210 KMGFLLADEAMPTMEKGRG--NFLSAATDLAIQFLSKDNSAFFIMSEGSQIDWGGHANNA 267 Query: 345 YLALTEAVMFDSAIEKASQLTNEK-DTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQ 403 ++E FD AI A + +TL ++T+DH GG+TL A N + Sbjct: 268 SYLISEINDFDDAIGTALAFAKKDGNTLVIVTSDHET----GGFTLA-------AKKNKR 316 Query: 404 DGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARG 463 + S S GP + S+ H + +FA G Sbjct: 317 EDGSEYSDYTEIGPTF----------------------------STGGHSATLIPVFAYG 348 Query: 464 PQAHLVHGVQEQNYIAH 480 P + G+ E N I H Sbjct: 349 PGSEEFIGIYENNEIFH 365 >3A52-A nrPDB Length = 400 Score = 96.3 bits (238), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 117/455 (25%), Positives = 188/455 (41%), Gaps = 93/455 (20%) Query: 56 LILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGT 115 +I+ +GDGMG +A R + P T + DR + A T Sbjct: 3 MIIMVGDGMGPAYTSAYRYFQDN----------------PDTEEIEQTVFDRLLVGMAST 46 Query: 116 ATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEV-----FSVMHRAKKAGKSVGVVTTTR 170 A G + + A F N ++ ++M AK G S GV T + Sbjct: 47 YPARESGYVTDSAASATALATGFKSYNGAIAVDINKRPLTTIMQMAKARGMSTGVAVTAQ 106 Query: 171 VQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPK 230 V HA+PA H +R Y + IA ++ + D DVILGGGRK+ Sbjct: 107 VNHATPAAFLTHNESRKNY--------------EAIAADMLKS-DADVILGGGRKYF--- 148 Query: 231 GTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFE 290 S LV ++ AK G +++ QL +Q +++GLF Sbjct: 149 -------------------SEALVSQFSAK--GYQHITELAQLDSITQ----PKVLGLFA 183 Query: 291 PTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTE 350 ++ + ++ + +L+++T+ ++ LLS+N +GF L VEG ID H A+ E Sbjct: 184 EVQLPWVIDDTDA--NTLSKLTQKSLDLLSQNEKGFVLLVEGSLIDWAGHNNDIATAMAE 241 Query: 351 AVMFDSAIEKASQLTNEK-DTLTLITADHS----HVFAFGGYTL-----RGTSI----FG 396 F +AIE Q + DTL ++TADH+ + A G Y +G S Sbjct: 242 MQGFANAIEVVEQYIRQHPDTLLVVTADHNTGGLSIGANGEYQWDTKLPKGISASPASIA 301 Query: 397 LAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAE-----SGDVNYKQ----QAAVPL 447 + A D ++ + G+ +NS +T+A + +V K+ ++ Sbjct: 302 THAIAADDWQAGVN----QQLGFDVNSTELQQLTNARMQGKSTLEVALKKIIDTRSYTGW 357 Query: 448 SSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVM 482 ++ H G DV +FA GP A L G Q+ +IA M Sbjct: 358 TTSGHTGVDVQVFAMGPAADLFKGNQDNTHIAEKM 392 >2X98-A nrPDB Length = 431 Score = 77.0 bits (188), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 128/456 (28%), Positives = 188/456 (41%), Gaps = 95/456 (20%) Query: 53 AKNLILFLGDGMGVPTVTATRILKG------QLGGHLGP-ETPLAMDHFPFTALSKTYNV 105 A N I ++ DGMG ++A R L + ++ P ETP D F T+ Sbjct: 4 AANAIAYIVDGMGQTQISAARYLNAYKTAPERFPLNVSPAETPTGFDAFSSRGSMTTFPD 63 Query: 106 D--RQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSV 163 D DSA ATA+ GVK IG Q + V +V+ RA G + Sbjct: 64 DPYETTTDSAAAATAFASGVKTYNGAIGGV------QTSGGGFQRVDTVLERASAQGYAT 117 Query: 164 GVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGG 223 G++TTT HA+PA AH +R + +IA Q I DVILGG Sbjct: 118 GLITTTEATHATPAAFAAHVEDRGNQT--------------EIARQYIEETQPDVILGGQ 163 Query: 224 RKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVT 283 R+ ++ D+ G +D+ A+ G +L A DP V Sbjct: 164 RR----------DFEADASNGGTLVDA--------ARDNGYTIAETAAEL-DAVDDPPV- 203 Query: 284 RLMGLF-EPTEMKYDVNRN---ASADPSLAEMTEVAVRLLSR--NP-QGFYLFVEGGRID 336 +GLF + + + Y ++R + P+L M + V LLS +P +GF+L VE GR+D Sbjct: 204 --LGLFSQESHLDYYLDRKNDPENTQPNLDAMVDAGVDLLSSAGDPDKGFFLLVESGRVD 261 Query: 337 QGHHAGTAYLALTEAVMFDSAIEKASQL-----TNEKDTLTLITADHSHVFAFGGYTLRG 391 HAG A A ++ A + A QL T + T + T DH GG TL Sbjct: 262 ---HAGHANYPAQVAEQYE-ATQVAGQLVEYAETTAEPTFLVSTGDHE----CGGLTLGR 313 Query: 392 TSIFGLA--PLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESG-------------- 435 S + + L AQ K+ TS L G V ++ ++ A +G Sbjct: 314 DSPYEVEYDVLAAQ--KATTSRLRDLLAG-VRSADELESIVAAHTGITALTDREVAKLRD 370 Query: 436 -----DVNYKQQAAVPLSSETHGGEDVAIFARGPQA 466 ++A + +++ H G DV +FA GP A Sbjct: 371 APGSISTILAERAGIAFTTDGHTGTDVPVFAHGPNA 406 >2MLY-B nrPDB Length = 151 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 40/125 (32%), Positives = 57/125 (45%), Gaps = 24/125 (19%) Query: 27 ENPVFWNQKAKEALDV---AKKLQPIQTSA----------KNLILFLGDGMGVPTVTATR 73 E PV N+ A+ + A++L QT+A KN+IL +GDGMG +TA R Sbjct: 26 EMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAAR 85 Query: 74 ILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQ------VPDSAGTATAYLCGVKANY 127 GG +D P T Y ++++ V DSA +ATA+ GVK Sbjct: 86 NYAEGAGGFFK-----GIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYN 140 Query: 128 KTIGV 132 +GV Sbjct: 141 GALGV 145 >2DPN-A nrPDB Length = 495 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 15/112 (13%) Query: 393 SIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTD---------AESGDVNYKQQA 443 ++FG A L +GK YG G +LN+G RP +++ + G Y + Sbjct: 246 ALFGQAALGGGEGKCT----YGTGAFLLLNTGKRPVLSEKGLLATVAWSLGGRATYALEG 301 Query: 444 AVPLSSETHGG-EDVAIFARGPQAH-LVHGVQEQNYIAHVMAFAGCLEPYTD 493 ++ ++ G ++V + + L V++ + V AF G PY D Sbjct: 302 SLFVAGAAVGWLKEVGLIRESAEVEALAASVEDTGDVYFVPAFTGLGAPYWD 353 >2MLZ-B nrPDB Length = 114 Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust. Identities = 36/143 (25%), Positives = 56/143 (39%), Gaps = 35/143 (24%) Query: 345 YLALTEAVMFDSAIEKASQLTN-EKDTLTLITADHSHVFAFGGYTLRGTSIFGLA-PLNA 402 ++ + E V D A+++A + E +TL ++TADH+H T GL LN Sbjct: 1 HMQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQI---VAPDTKAPGLTQALNT 57 Query: 403 QDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFAR 462 +DG V++ GN S+ H G + I A Sbjct: 58 KDGAV-----------MVMSYGNSEE-------------------DSQEHTGSQLRIAAY 87 Query: 463 GPQAHLVHGVQEQNYIAHVMAFA 485 GP A V G+ +Q + + M A Sbjct: 88 GPHAANVVGLTDQTDLFYTMKAA 110 >5W16-A nrPDB Length = 278 Score = 30.8 bits (68), Expect = 1.7, Method: Compositional matrix adjust. Identities = 32/147 (21%), Positives = 54/147 (36%), Gaps = 13/147 (8%) Query: 122 GVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYA 181 GVKA +++A VF V+ A +A + V Q +G Y Sbjct: 88 GVKAIVVACNTASSAALPDLAEDLSVPVFGVVEPAARAARGFRKVGLIGTQATVESGAYP 147 Query: 182 HTVNRDWYSDADMPSSALQEGCKDIATQLI--------SNMDIDVILGGGRKFMFPKGTP 233 V+ W + ++EG D L+ + D++ ++ G + F KG Sbjct: 148 RYVDLAWAKACPLFVPLVEEGLWDDPVALLVARHYLEDAPKDLEALILGCTHYPFLKGAI 207 Query: 234 DPEYPGDSDQSGVRLDSRNLVEEWLAK 260 PG + LDS L + +A+ Sbjct: 208 GAVLPGVA-----LLDSAELTAQEVAR 229 >3S8M-A nrPDB Length = 422 Score = 30.8 bits (68), Expect = 1.7, Method: Compositional matrix adjust. Identities = 34/141 (24%), Positives = 60/141 (42%), Gaps = 24/141 (17%) Query: 145 FGNEVFSVMHR----AKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQ 200 FG + V A KAG + + +HA AG Y+ ++N D +SDA A Sbjct: 85 FGADTLGVFFEKPGTASKAGTAGWYNSAAFDKHAKAAGLYSKSINGDAFSDA-----ARA 139 Query: 201 EGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAK 260 + + I T++ +D+ V + +P + PG + R+ ++ Sbjct: 140 QVIELIKTEMGGQVDLVV---------YSLASPVRKLPGSGEV------KRSALKPIGQT 184 Query: 261 YQGTRYVWNREQLMQASQDPA 281 Y T N++ ++QAS +PA Sbjct: 185 YTATAIDTNKDTIIQASIEPA 205 >1JFX-A nrPDB Length = 217 Score = 28.9 bits (63), Expect = 6.1, Method: Compositional matrix adjust. Identities = 26/99 (26%), Positives = 44/99 (44%), Gaps = 6/99 (6%) Query: 335 IDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSI 394 ID H G+ + ++ A KA++ TN KD +A++++ + G +RG Sbjct: 8 IDVSHWQGSINWSSVKSAGMSFAYIKATEGTNYKDDR--FSANYTNAYNAG--IIRGA-- 61 Query: 395 FGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAE 433 + A NA G + NG G+ ++ P V D E Sbjct: 62 YHFARPNASSGTAQADYFASNGGGWSRDNRTLPGVLDIE 100 >4Z2R-A nrPDB Length = 592 Score = 28.5 bits (62), Expect = 7.4, Method: Compositional matrix adjust. Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 16/79 (20%) Query: 198 ALQEGCKDIATQLISNMDIDVI-LGGGR----------KFMFPKGTPDPEYPGDSD---Q 243 A +EG K A L MD +I LGGG + +FP GTPDP + D + Q Sbjct: 412 ASEEGAKRRAA-LRKAMDATIIGLGGGHGVELNQRYVSRAVFPDGTPDPGFVRDQEFFYQ 470 Query: 244 SGVRLDSRNLVEEWLAKYQ 262 + R + +L WL + Q Sbjct: 471 ASTRPGA-HLPHVWLTENQ 488 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4KJD-A nrPDB 724 0.0 3MK1-A nrPDB 682 0.0 1SHQ-A nrPDB 525 e-149 5JTL-E nrPDB 357 6e-99 3E2D-A nrPDB 334 4e-92 3A52-A nrPDB 330 1e-90 3WBH-A nrPDB 324 7e-89 2W5W-A nrPDB 319 2e-87 2X98-A nrPDB 276 2e-74 2MLY-B nrPDB 114 8e-26 Sequences not found previously or not previously below threshold: 2MLZ-B nrPDB 87 2e-17 2MLX-B nrPDB 57 2e-08 1DJX-A nrPDB 38 0.007 2ZKT-A nrPDB 38 0.010 5KGM-A nrPDB 38 0.011 2VQR-A nrPDB 35 0.062 2IFY-A nrPDB 34 0.13 3NVL-A nrPDB 34 0.17 2W8S-A nrPDB 34 0.17 4YZZ-A nrPDB 33 0.40 4UPH-A nrPDB 31 1.0 3IGZ-B nrPDB 31 1.8 5VPU-A nrPDB 31 1.9 1O99-A nrPDB 29 3.9 3LM6-A nrPDB 29 7.3 >4KJD-A nrPDB Length = 488 Score = 724 bits (1869), Expect = 0.0, Method: Composition-based stats. Identities = 482/484 (99%), Positives = 483/484 (99%) Query: 21 VIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLG 80 VIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLG Sbjct: 1 VIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLG 60 Query: 81 GHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQ 140 GHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQ Sbjct: 61 GHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQ 120 Query: 141 CNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQ 200 CNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQ Sbjct: 121 CNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQ 180 Query: 201 EGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAK 260 EGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAK Sbjct: 181 EGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAK 240 Query: 261 YQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLS 320 YQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLS Sbjct: 241 YQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLS 300 Query: 321 RNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSH 380 RNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSH Sbjct: 301 RNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSH 360 Query: 381 VFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYK 440 VFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYK Sbjct: 361 VFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYK 420 Query: 441 QQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPA 500 QQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPA Sbjct: 421 QQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPA 480 Query: 501 DENR 504 DE+ Sbjct: 481 DEHH 484 >3MK1-A nrPDB Length = 484 Score = 682 bits (1760), Expect = 0.0, Method: Composition-based stats. Identities = 367/480 (76%), Positives = 416/480 (86%) Query: 21 VIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLG 80 +IPVEEENP FWN++A EAL AKKLQP QT+AKNLI+FLGDGMGV TVTA RILKGQ Sbjct: 1 IIPVEEENPDFWNREAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKK 60 Query: 81 GHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQ 140 LGPE PLAMD FP+ ALSKTYNVD+ VPDS TATAYLCGVK N++TIG+SAAARFNQ Sbjct: 61 DKLGPEIPLAMDRFPYVALSKTYNVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQ 120 Query: 141 CNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQ 200 CN+T GNEV SVM+RAKKAGKSVGVVTTTRVQHASPAGTYAHTVNR+WYSDAD+P+SA Q Sbjct: 121 CNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADVPASARQ 180 Query: 201 EGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAK 260 EGC+DIATQLISNMDIDVILGGGRK+MF GTPDPEYP D Q G RLD +NLV+EWLAK Sbjct: 181 EGCQDIATQLISNMDIDVILGGGRKYMFRMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAK 240 Query: 261 YQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLS 320 QG RYVWNR +LMQAS DP+VT LMGLFEP +MKY+++R+++ DPSL EMTE A+RLLS Sbjct: 241 RQGARYVWNRTELMQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALRLLS 300 Query: 321 RNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSH 380 RNP+GF+LFVEGGRID GHH AY ALTE +MFD AIE+A QLT+E+DTL+L+TADHSH Sbjct: 301 RNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSH 360 Query: 381 VFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYK 440 VF+FGGY LRG+SIFGLAP A+D K+YT +LYGNGPGYVL G RP+VT++ESG Y+ Sbjct: 361 VFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYR 420 Query: 441 QQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPA 500 QQ+AVPL ETH GEDVA+FARGPQAHLVHGVQEQ +IAHVMAFA CLEPYT C LAPPA Sbjct: 421 QQSAVPLDEETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPPA 480 >1SHQ-A nrPDB Length = 478 Score = 525 bits (1351), Expect = e-149, Method: Composition-based stats. Identities = 201/474 (42%), Positives = 279/474 (58%), Gaps = 17/474 (3%) Query: 26 EENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGP 85 EE+ +WN+ A++ALD ++ + AKN+I FLGDGM + TVTA RI KG L G Sbjct: 1 EEDKAYWNKDAQDALDKQLGIKLREKQAKNVIFFLGDGMSLSTVTAARIYKGGLTGKFER 60 Query: 86 ETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTF 145 E ++ + F F ALSKTYN D+QV DSA +ATAYL GVK N IG+ A C+ Sbjct: 61 E-KISWEEFDFAALSKTYNTDKQVTDSAASATAYLTGVKTNQGVIGLDANTVRTNCSYQL 119 Query: 146 GNEVFS--VMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQ-EG 202 +F+ + H ++AG+S GVVT+TRV HA+PAGTYAH +RDW +D+D+ E Sbjct: 120 DESLFTYSIAHWFQEAGRSTGVVTSTRVTHATPAGTYAHVADRDWENDSDVVHDREDPEI 179 Query: 203 CKDIATQLISN---MDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWL- 258 C DIA QL+ + VI+GGGR+ FP+ D E G R D ++L+ +WL Sbjct: 180 CDDIAEQLVFREPGKNFKVIMGGGRRGFFPEEALDIE----DGIPGEREDGKHLITDWLD 235 Query: 259 -AKYQGTR--YVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVA 315 QG YVWNR+ L+ A LMGLF T + + R+A DP+L EMT+VA Sbjct: 236 DKASQGATASYVWNRDDLL-AVDIRNTDYLMGLFSYTHLDTVLTRDAEMDPTLPEMTKVA 294 Query: 316 VRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLIT 375 + +L+++ GF+L VEGGRID HHA +L E + + A+ A +T+ ++T+ L+T Sbjct: 295 IEMLTKDENGFFLLVEGGRIDHMHHANQIRQSLAETLDMEEAVSMALSMTDPEETIILVT 354 Query: 376 ADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGY-VLNSGNRPNVTDAES 434 ADH H GY R T I A ++ D + YT + YG+GPGY + G R T+ + Sbjct: 355 ADHGHTLTITGYADRNTDILDFAGISDLDDRRYTILDYGSGPGYHITEDGKRYEPTEEDL 414 Query: 435 GDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCL 488 D+N++ +A P S TH G DV I+ GP AHL GV E+NYI H +A+A C+ Sbjct: 415 KDINFRYASAAPKHSVTHDGTDVGIWVNGPFAHLFTGVYEENYIPHALAYAACV 468 >5JTL-E nrPDB Length = 471 Score = 357 bits (916), Expect = 6e-99, Method: Composition-based stats. Identities = 143/506 (28%), Positives = 215/506 (42%), Gaps = 110/506 (21%) Query: 27 ENPVFWNQKAKEALDV---AKKLQPIQTSA----------KNLILFLGDGMGVPTVTATR 73 E PV N+ A+ + A++L QT+A KN+IL +GDGMG +TA R Sbjct: 25 EMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAAR 84 Query: 74 ILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQ------VPDSAGTATAYLCGVKANY 127 GG +D P T Y ++++ V DSA +ATA+ GVK Sbjct: 85 NYAEGAGGFFK-----GIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYN 139 Query: 128 KTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRD 187 +GV + + +++ AK AG + G V+T +Q A+PA AH +R Sbjct: 140 GALGVDIHEKDHP----------TILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRK 189 Query: 188 WY----SDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQ 243 Y + P +AL++G K T+ + N DV LGGG K F + E+ G Sbjct: 190 CYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAK-TFAETATAGEWQG---- 244 Query: 244 SGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMK-------- 295 + L E+ A+ +G + V + L ++ L+GLF M Sbjct: 245 -------KTLREQ--AQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKA 295 Query: 296 -YDVN-------------RNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHA 341 Y N RN S P+LA+MT+ A+ LLS+N +GF+L VEG ID+ HA Sbjct: 296 TYHGNIDKPAVTCTPNPQRNDSV-PTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHA 354 Query: 342 GTAYLALTEAVMFDSAIEKASQLTNEK-DTLTLITADHSHVFAFGGYTLRGTSIFGLA-P 399 + E V D A+++A + ++ +TL ++TADH+H T GL Sbjct: 355 ANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQI---VAPDTKAPGLTQA 411 Query: 400 LNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAI 459 LN +DG V++ GN S+ H G + I Sbjct: 412 LNTKDGAV-----------MVMSYGNSEE-------------------DSQEHTGSQLRI 441 Query: 460 FARGPQAHLVHGVQEQNYIAHVMAFA 485 A GP A V G+ +Q + + M A Sbjct: 442 AAYGPHAANVVGLTDQTDLFYTMKAA 467 >3E2D-A nrPDB Length = 502 Score = 334 bits (857), Expect = 4e-92, Method: Composition-based stats. Identities = 110/351 (31%), Positives = 163/351 (46%), Gaps = 51/351 (14%) Query: 54 KNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPF---TALSKTYNVDRQVP 110 KN+IL +GDGMG V Q + A+ S T+ D V Sbjct: 4 KNVILMIGDGMGPQQVGLLETYANQAPNSIYKGNKTAIYQLAQEGVIGSSLTHPEDAIVV 63 Query: 111 DSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTR 170 DSA +AT G+ ++ + IG+ + GN V +V+ +AKKAGK+ G+V+ TR Sbjct: 64 DSACSATMLATGIYSSSEVIGIDSQ----------GNHVETVLEKAKKAGKATGLVSDTR 113 Query: 171 VQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPK 230 + HA+PA AH +R + IA+ +++ DV+L GG + PK Sbjct: 114 LTHATPASFAAHQPHRSLEN--------------QIASDMLA-TGADVMLSGGLRHWIPK 158 Query: 231 GTPDPE---------YPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPA 281 T D GD R D RNL+ E A+ G + +NR L A D Sbjct: 159 STNDKGETYKQLEKLTQGDVYLKSKRKDDRNLLTE--AEKDGYQLAFNRNMLDDAKGD-- 214 Query: 282 VTRLMGLFEPTEMKYDV------NRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRI 335 +L+GLF + M + PSL EMT+ A+ +LS++ GF+L VEGG+I Sbjct: 215 --KLLGLFAYSGMDDGIAYSNKKKSGERTQPSLKEMTQKALNILSKDEDGFFLMVEGGQI 272 Query: 336 DQGHHAGTAYLALTEAVMFDSAIEKASQLTNE-KDTLTLITADHSHVFAFG 385 D H+ A L E + FD AI+ + + +DT+ ++TADH +FG Sbjct: 273 DWAGHSNDAGTMLHELLKFDEAIQTVYEWAKDREDTIVIVTADHE-TGSFG 322 >3A52-A nrPDB Length = 400 Score = 330 bits (845), Expect = 1e-90, Method: Composition-based stats. Identities = 117/455 (25%), Positives = 188/455 (41%), Gaps = 93/455 (20%) Query: 56 LILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGT 115 +I+ +GDGMG +A R + P T + DR + A T Sbjct: 3 MIIMVGDGMGPAYTSAYRYFQDN----------------PDTEEIEQTVFDRLLVGMAST 46 Query: 116 ATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEV-----FSVMHRAKKAGKSVGVVTTTR 170 A G + + A F N ++ ++M AK G S GV T + Sbjct: 47 YPARESGYVTDSAASATALATGFKSYNGAIAVDINKRPLTTIMQMAKARGMSTGVAVTAQ 106 Query: 171 VQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPK 230 V HA+PA H +R Y + IA ++ + D DVILGGGRK+ Sbjct: 107 VNHATPAAFLTHNESRKNY--------------EAIAADMLKS-DADVILGGGRKYF--- 148 Query: 231 GTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFE 290 S LV ++ AK G +++ QL +Q +++GLF Sbjct: 149 -------------------SEALVSQFSAK--GYQHITELAQLDSITQ----PKVLGLFA 183 Query: 291 PTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTE 350 ++ + ++ + +L+++T+ ++ LLS+N +GF L VEG ID H A+ E Sbjct: 184 EVQLPWVIDDTDA--NTLSKLTQKSLDLLSQNEKGFVLLVEGSLIDWAGHNNDIATAMAE 241 Query: 351 AVMFDSAIEKASQLTNEK-DTLTLITADHSH----VFAFGGYTL-----RGTSI----FG 396 F +AIE Q + DTL ++TADH+ + A G Y +G S Sbjct: 242 MQGFANAIEVVEQYIRQHPDTLLVVTADHNTGGLSIGANGEYQWDTKLPKGISASPASIA 301 Query: 397 LAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAE-----SGDVNYKQ----QAAVPL 447 + A D ++ + G+ +NS +T+A + +V K+ ++ Sbjct: 302 THAIAADDWQAGVN----QQLGFDVNSTELQQLTNARMQGKSTLEVALKKIIDTRSYTGW 357 Query: 448 SSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVM 482 ++ H G DV +FA GP A L G Q+ +IA M Sbjct: 358 TTSGHTGVDVQVFAMGPAADLFKGNQDNTHIAEKM 392 >3WBH-A nrPDB Length = 527 Score = 324 bits (829), Expect = 7e-89, Method: Composition-based stats. Identities = 106/347 (30%), Positives = 158/347 (45%), Gaps = 47/347 (13%) Query: 54 KNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFP---FTALSKTYNVDRQVP 110 KN+IL +GDGMG V Q + P A S T+ D V Sbjct: 33 KNVILMIGDGMGPQQVGLLETYANQAPDSIYDGEPTAFHQLAKEGVVGFSLTHPEDAVVV 92 Query: 111 DSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTR 170 DSA +AT G+ + + IG+ A GN V +V+ A+ GK+ G+V+ TR Sbjct: 93 DSACSATQLASGIYSGSEVIGIDAE----------GNPVETVLELAQARGKATGLVSDTR 142 Query: 171 VQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPK 230 + HA+PA AH +R + +IA ++ + DV+L GG + P+ Sbjct: 143 LTHATPAAFAAHQPHRSLEN--------------EIAVDML-EVGPDVMLSGGLRHWVPQ 187 Query: 231 GT-PDPE----YPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRL 285 D E G + + R D RNL+ E + K G ++REQL D +L Sbjct: 188 SASEDAEVTSLMDGAYEPASKRQDDRNLLAEAVEK--GYGLAFSREQLEADQSD----KL 241 Query: 286 MGLFEPTEMKYDV------NRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGH 339 +GLF + M + + +P+L EMT+ A+ L ++ GF+L VEGG+ID Sbjct: 242 LGLFANSGMADGIEYRNTRDDADRREPTLHEMTQAALNRLEQDEDGFFLMVEGGQIDWAG 301 Query: 340 HAGTAYLALTEAVMFDSAIEKASQLTN-EKDTLTLITADHSHVFAFG 385 H+ A L E V F+ A++ +DT+ L+TADH AFG Sbjct: 302 HSNDAGTMLNEMVKFEEAVQGVYDWAKGREDTVILVTADHE-TGAFG 347 >2W5W-A nrPDB Length = 375 Score = 319 bits (817), Expect = 2e-87, Method: Composition-based stats. Identities = 109/439 (24%), Positives = 169/439 (38%), Gaps = 98/439 (22%) Query: 45 KLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYN 104 K +P + KN+IL + DG G+ +++T K F L KT + Sbjct: 26 KNEPQLKTPKNVILLISDGAGLSQISSTFYFKSGTPN---------YTQFKNIGLIKTSS 76 Query: 105 VDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVG 164 V DSA ATA+ CG+K IGV+ + V S++ A G Sbjct: 77 SREDVTDSASGATAFSCGIKTYNAAIGVADDS----------TAVKSIVEIAALNNIKTG 126 Query: 165 VVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGR 224 VV T+ + A+PA YAH +NR ++IA + + D+D GGG Sbjct: 127 VVATSSITDATPASFYAHALNRGLE--------------EEIAMDM-TESDLDFFAGGGL 171 Query: 225 KFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTR 284 + R D +++ LA +G ++ N L S A R Sbjct: 172 NYF-----------------TKRKDKKDV----LAILKGNQFTINTTALTDFSS-IASNR 209 Query: 285 LMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTA 344 MG E + + L+ T++A++ LS++ F++ EG +ID G HA A Sbjct: 210 KMGFLLADEAMPTMEKGRG--NFLSAATDLAIQFLSKDNSAFFIMSEGSQIDWGGHANNA 267 Query: 345 YLALTEAVMFDSAIEKASQLTNEK-DTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQ 403 ++E FD AI A + +TL ++T+DH GG+TL A N + Sbjct: 268 SYLISEINDFDDAIGTALAFAKKDGNTLVIVTSDHET----GGFTLA-------AKKNKR 316 Query: 404 DGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARG 463 + S S GP + S+ H + +FA G Sbjct: 317 EDGSEYSDYTEIGPTF----------------------------STGGHSATLIPVFAYG 348 Query: 464 PQAHLVHGVQEQNYIAHVM 482 P + G+ E N I H + Sbjct: 349 PGSEEFIGIYENNEIFHKI 367 >2X98-A nrPDB Length = 431 Score = 276 bits (705), Expect = 2e-74, Method: Composition-based stats. Identities = 123/464 (26%), Positives = 184/464 (39%), Gaps = 91/464 (19%) Query: 53 AKNLILFLGDGMGVPTVTATRILK------GQLGGHLGP-ETPLAMDHFPFTALSKTYNV 105 A N I ++ DGMG ++A R L + ++ P ETP D F T+ Sbjct: 4 AANAIAYIVDGMGQTQISAARYLNAYKTAPERFPLNVSPAETPTGFDAFSSRGSMTTFPD 63 Query: 106 D--RQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSV 163 D DSA ATA+ GVK IG Q + V +V+ RA G + Sbjct: 64 DPYETTTDSAAAATAFASGVKTYNGAIGGV------QTSGGGFQRVDTVLERASAQGYAT 117 Query: 164 GVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGG 223 G++TTT HA+PA AH +R + +IA Q I DVILGG Sbjct: 118 GLITTTEATHATPAAFAAHVEDRGNQT--------------EIARQYIEETQPDVILGGQ 163 Query: 224 RKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVT 283 R+ ++ D+ G +D+ A+ G +L A DP V Sbjct: 164 RR----------DFEADASNGGTLVDA--------ARDNGYTIAETAAEL-DAVDDPPV- 203 Query: 284 RLMGLF-EPTEMKYDVNRN---ASADPSLAEMTEVAVRLLSR--NP-QGFYLFVEGGRID 336 +GLF + + + Y ++R + P+L M + V LLS +P +GF+L VE GR+D Sbjct: 204 --LGLFSQESHLDYYLDRKNDPENTQPNLDAMVDAGVDLLSSAGDPDKGFFLLVESGRVD 261 Query: 337 QGHHAGTAYLALTEAVMFDSAIEKASQL-----TNEKDTLTLITADHSHVFAFGGYTLRG 391 HA A + A + A QL T + T + T DH GG TL Sbjct: 262 HAGHAN---YPAQVAEQY-EATQVAGQLVEYAETTAEPTFLVSTGDHE----CGGLTLGR 313 Query: 392 TSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESG---------------- 435 S + + K+ TS L G V ++ ++ A +G Sbjct: 314 DSPYEVEYDVLAAQKATTSRLRDLLAG-VRSADELESIVAAHTGITALTDREVAKLRDAP 372 Query: 436 ---DVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQN 476 ++A + +++ H G DV +FA GP A ++ Sbjct: 373 GSISTILAERAGIAFTTDGHTGTDVPVFAHGPNAARFDAARDNT 416 >2MLY-B nrPDB Length = 151 Score = 114 bits (286), Expect = 8e-26, Method: Composition-based stats. Identities = 40/131 (30%), Positives = 58/131 (44%), Gaps = 24/131 (18%) Query: 27 ENPVFWNQKAKEALDV---AKKLQPIQTSA----------KNLILFLGDGMGVPTVTATR 73 E PV N+ A+ + A++L QT+A KN+IL +GDGMG +TA R Sbjct: 26 EMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAAR 85 Query: 74 ILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQ------VPDSAGTATAYLCGVKANY 127 GG +D P T Y ++++ V DSA +ATA+ GVK Sbjct: 86 NYAEGAGGFFK-----GIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYN 140 Query: 128 KTIGVSAAARF 138 +GV + Sbjct: 141 GALGVDIHEKD 151 >2MLZ-B nrPDB Length = 114 Score = 86.9 bits (213), Expect = 2e-17, Method: Composition-based stats. Identities = 35/141 (24%), Positives = 55/141 (39%), Gaps = 35/141 (24%) Query: 347 ALTEAVMFDSAIEKASQLTNEK-DTLTLITADHSHVFAFGGYTLRGTSIFGLA-PLNAQD 404 + E V D A+++A + ++ +TL ++TADH+H T GL LN +D Sbjct: 3 QIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQI---VAPDTKAPGLTQALNTKD 59 Query: 405 GKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGP 464 G V++ GN S+ H G + I A GP Sbjct: 60 GAV-----------MVMSYGNSEE-------------------DSQEHTGSQLRIAAYGP 89 Query: 465 QAHLVHGVQEQNYIAHVMAFA 485 A V G+ +Q + + M A Sbjct: 90 HAANVVGLTDQTDLFYTMKAA 110 >2MLX-B nrPDB Length = 93 Score = 56.8 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 21/82 (25%), Positives = 32/82 (39%), Gaps = 14/82 (17%) Query: 214 MDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQL 273 DV LGGG K F + E+ G + L E+ A+ +G + V + L Sbjct: 3 ARADVTLGGGAK-TFAETATAGEWQG-----------KTLREQ--AQARGYQLVSDAASL 48 Query: 274 MQASQDPAVTRLMGLFEPTEMK 295 ++ L+GLF M Sbjct: 49 NSVTEANQQKPLLGLFADGNMP 70 >1DJX-A nrPDB Length = 624 Score = 38.3 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 35/184 (19%), Positives = 66/184 (35%), Gaps = 21/184 (11%) Query: 338 GHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLIT--AD---HSHVFAFGGYTLRGT 392 G A + A M D A+ Q ++D L L+ +D + FGG++ GT Sbjct: 321 GSEATDVSDEVEAAEMEDEAVRSQVQHKPKEDKLKLVPELSDMIIYCKSVHFGGFSSPGT 380 Query: 393 SIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETH 452 S + + +L +G G+V ++ + + +++ Sbjct: 381 SGQAFYEMASFSESRALRLLQESGNGFVRHNVS------------CLSRIYPAGWRTDSS 428 Query: 453 GGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCG-LAPPADENRPTTPVQN 511 V ++ G Q + + Q + + GC + CG + PA P T + Sbjct: 429 NYSPVEMWNGGCQ---IVALNFQTPGPEMDVYLGCFQDNGGCGYVLKPAFLRDPNTTFNS 485 Query: 512 SAIT 515 A+T Sbjct: 486 RALT 489 >2ZKT-A nrPDB Length = 412 Score = 38.0 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 22/107 (20%), Positives = 38/107 (35%), Gaps = 5/107 (4%) Query: 276 ASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTE--VAVRLLSRNPQGFYLFVEGG 333 A+ AV + G+ A+ + + EM + AV LL ++ ++F+ Sbjct: 246 AAGVIAVALVKGVARAVGFDVYTPEGATGEYNTNEMAKAKKAVELL-KDYD--FVFLHFK 302 Query: 334 RIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSH 380 D H L D I + ++ + IT DHS Sbjct: 303 PTDAAGHDNKPKLKAELIERADRMIGYILDHVDLEEVVIAITGDHST 349 >5KGM-A nrPDB Length = 552 Score = 38.0 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 25/136 (18%), Positives = 51/136 (37%), Gaps = 4/136 (2%) Query: 250 SRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLA 309 ++N++ EWLA+ + +++ + L FE E + + Sbjct: 336 NKNVLAEWLAEQKVSQFHCAETEKYAHVTFFFNGGLEKQFEGEERCLVPSPKVATYDLQP 395 Query: 310 EMTEVAV--RLLSRNPQGF--YLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLT 365 EM+ V +++ + G ++ D H G A+ D AI + + T Sbjct: 396 EMSAAGVADKMIEQLEAGTHPFIMCNFAPPDMVGHTGVYEAAVKACEATDIAIGRIYEAT 455 Query: 366 NEKDTLTLITADHSHV 381 + ++TADH + Sbjct: 456 QKHGYSLMVTADHGNA 471 >2VQR-A nrPDB Length = 543 Score = 35.3 bits (79), Expect = 0.062, Method: Composition-based stats. Identities = 33/168 (19%), Positives = 53/168 (31%), Gaps = 19/168 (11%) Query: 326 FYLFVEGG--RIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNE----KDTLTLITADHS 379 F+ EG +D+ D + + +E DTL + T+DH Sbjct: 296 FFQGAEGSGATLDEAELRQMRATYCGLITEVDDCLGRVFSYLDETGQWDDTLIIFTSDHG 355 Query: 380 ------HVFAFGGYTLRGTSIFGL---APLNAQDGK--SYTSILYGNGPG-YVLNSGNRP 427 H+ GY I + A NA+ G S + P G P Sbjct: 356 EQLGDHHLLGKIGYNDPSFRIPLVIKDAGENARAGAIESGFTESIDVMPTILDWLGGKIP 415 Query: 428 NVTDAESGDVNYKQQAAVPLSSETHGGEDVA-IFARGPQAHLVHGVQE 474 + D S + +E H D ++ PQ+ L G+ + Sbjct: 416 HACDGLSLLPFLSEGRPQDWRTELHYEYDFRDVYYSEPQSFLGLGMND 463 >2IFY-A nrPDB Length = 508 Score = 34.5 bits (77), Expect = 0.13, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 30/75 (40%), Gaps = 1/75 (1%) Query: 307 SLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTN 366 S+ E+T+ V + + + + D H+G + D + K + Sbjct: 373 SIYEVTDALVNEIENDKHD-VIILNFANCDMVGHSGMMEPTIKAVEATDECLGKVVEAIL 431 Query: 367 EKDTLTLITADHSHV 381 KD + LITADH + Sbjct: 432 AKDGVALITADHGNA 446 >3NVL-A nrPDB Length = 571 Score = 34.1 bits (76), Expect = 0.17, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 33/73 (45%), Gaps = 1/73 (1%) Query: 309 AEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEK 368 E+T+ AV + ++ + + + D H G +T D ++++ + + Sbjct: 418 KEITDAAVDAI-KSGKYDMIRINYPNGDMVGHTGDLKATITSLEAVDQSLQRLKEAVDSV 476 Query: 369 DTLTLITADHSHV 381 + + LITADH + Sbjct: 477 NGVFLITADHGNS 489 >2W8S-A nrPDB Length = 543 Score = 34.1 bits (76), Expect = 0.17, Method: Composition-based stats. Identities = 29/159 (18%), Positives = 47/159 (29%), Gaps = 19/159 (11%) Query: 326 FYLFVEGG--RIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNE----KDTLTLITADHS 379 F+ EG +D+G D + + +E DTL + T+DH Sbjct: 296 FFHGAEGSGATLDEGEIRQMRATYCGLITEIDDCLGRVFAYLDETGQWDDTLIIFTSDHG 355 Query: 380 ------HVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNS------GNRP 427 H+ GY I + Q+ + + V+ + G P Sbjct: 356 EQLGDHHLLGKIGYNAESFRIPLVIKDAGQNRHAGQIEEGFSESIDVMPTILEWLGGETP 415 Query: 428 NVTDAESGDVNYKQQAAVPLSSETHGGEDVA-IFARGPQ 465 D S + +E H D +F PQ Sbjct: 416 RACDGRSLLPFLAEGKPSDWRTELHYEFDFRDVFYDQPQ 454 >4YZZ-A nrPDB Length = 367 Score = 33.0 bits (73), Expect = 0.40, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 39/96 (40%), Gaps = 10/96 (10%) Query: 177 AGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDI-------DVILGGGRKFMFP 229 A + ++ W + +A + C + + ++++N D +I GG + FP Sbjct: 244 ASITSMVNDKAWEALPPAYQAAFEAACGEQSMRMLANYDARNPLALRKLIAGGAKVSFFP 303 Query: 230 KGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTR 265 K D Y S Q L +N ++ A Y G + Sbjct: 304 KEVMDAVYKA-SQQLWTELSEKN--PDFKAIYPGWK 336 >4UPH-A nrPDB Length = 547 Score = 31.4 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 33/170 (19%), Positives = 57/170 (33%), Gaps = 19/170 (11%) Query: 301 NASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLAL--TEAVMFDSAI 358 N A+ ++ + A+ L+ ++ F EG D +A A+ D+ + Sbjct: 277 NREAEQAVHPLLAFALPLIGKD--SFIYGGEGSASDWTSEDLSAIRAIYYGMIAEVDTQL 334 Query: 359 EKASQLTNE----KDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYG 414 + Q DTL + T+DH+ + G + + G F SY L Sbjct: 335 GRIWQALKNVGAWDDTLIIFTSDHAEM--MGDHWMLGKGGFF--------DGSYHVPLVI 384 Query: 415 NGPGYVLNSG-NRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARG 463 PG+ +G T A + + + GG V G Sbjct: 385 RDPGHPGGAGRQVERFTSAADIFPTLCDRLGLVPDNHLDGGTLVPFLEGG 434 >3IGZ-B nrPDB Length = 561 Score = 30.6 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 19/46 (41%) Query: 336 DQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHV 381 D H G +T D ++ K + + + ++TADH + Sbjct: 425 DMVGHTGDLKATITGVEAVDESLAKLKDAVDSVNGVYIVTADHGNS 470 >5VPU-A nrPDB Length = 523 Score = 30.6 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 42/242 (17%), Positives = 81/242 (33%), Gaps = 20/242 (8%) Query: 153 MHRAKKAG------KSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDI 206 + A A K+ + +VQ +R ++ + +++ Sbjct: 234 LELAYAANENDEFVKATRIGEIAKVQDGDSVVFMNFRADR----AREITRAFVEKDFAGF 289 Query: 207 ATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQS-GVRLDSRNLVEEWLAKYQGTR 265 +++ N+ V+L ++ P P + S G L S + +A+ + Sbjct: 290 ERKVVPNLSKFVMLT---RYQASIDAPVAYMPEELKNSLGEYLSSLGKTQLRIAETEKYA 346 Query: 266 YVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQG 325 +V + + P R++ + P YD+ SA E+ A+ + Sbjct: 347 HVTFFFSGGREDEYPGEKRIL-IPSPNVATYDLKPEMSAYEVTDELV-KAINSGEYD--- 401 Query: 326 FYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVFAFG 385 L V D H G A+ D+ + + + K LITADH +V Sbjct: 402 -LLVVNYANGDMVGHTGVFDAAVKAVEAVDTCLGRVYEAVMAKKGHMLITADHGNVEQMQ 460 Query: 386 GY 387 Y Sbjct: 461 DY 462 >1O99-A nrPDB Length = 511 Score = 29.5 bits (64), Expect = 3.9, Method: Composition-based stats. Identities = 13/72 (18%), Positives = 26/72 (36%), Gaps = 1/72 (1%) Query: 310 EMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKD 369 E+T+ ++ + + + D H+G + D + K K Sbjct: 378 EVTDALLKEIEADKYDAIIL-NYANPDMVGHSGKLEPTIKAVEAVDECLGKVVDAILAKG 436 Query: 370 TLTLITADHSHV 381 + +ITADH + Sbjct: 437 GIAIITADHGNA 448 >3LM6-A nrPDB Length = 346 Score = 28.7 bits (62), Expect = 7.3, Method: Composition-based stats. Identities = 26/165 (15%), Positives = 51/165 (30%), Gaps = 18/165 (10%) Query: 340 HAGTAYLALTEAVMFDSAIEKASQLTN--EKDTLTLITADHSHVFAFGGYTLRGTSI--- 394 H + E + + A+ A Q N + D L+ D + Y R I Sbjct: 45 HCNQKSWEMAERQLMEDAVNVALQKNNLTKDDIDLLLAGDLLNQNVTANYVARHLKIPFL 104 Query: 395 --FGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLS-SET 451 FG + + ++++ G L + + N T + P + + T Sbjct: 105 CMFGACSTSMETVAVASALVDGGFAKRALAATSSHNATAERQFRYPTEYGGQKPDTATST 164 Query: 452 HGGEDVAIFARGPQAHLVH----------GVQEQNYIAHVMAFAG 486 G + ++ P + G+ + + MA A Sbjct: 165 VTGSGAVVISQTPGDIQITSATVGKVSDLGITDPFDMGSAMAPAA 209 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.115 0.278 Lambda K H 0.267 0.0349 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,107,121 Number of Sequences: 36641 Number of extensions: 631496 Number of successful extensions: 1849 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 31 Number of HSP's successfully gapped in prelim test: 18 Number of HSP's that attempted gapping in prelim test: 1722 Number of HSP's gapped (non-prelim): 58 length of query: 540 length of database: 10,336,785 effective HSP length: 102 effective length of query: 438 effective length of database: 6,599,403 effective search space: 2890538514 effective search space used: 2890538514 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 61 (28.3 bits)