BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P15429 (434 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2XSX-A nrPDB 879 0.0 3B97-A nrPDB 761 0.0 3UJR-A nrPDB 759 0.0 1PDZ-A nrPDB 647 0.0 5WRO-A nrPDB 631 0.0 3OTR-A nrPDB 564 e-161 2XH7-A nrPDB 560 e-160 3QTP-A nrPDB 550 e-157 4G7F-A nrPDB 526 e-150 2PU1-A nrPDB 519 e-147 2PA6-A nrPDB 446 e-126 6BFZ-A nrPDB 436 e-122 5BOE-A nrPDB 427 e-120 5J04-A nrPDB 426 e-120 4Z1Y-A nrPDB 426 e-119 1IYX-A nrPDB 419 e-117 4MKS-A nrPDB 417 e-117 4A3R-A nrPDB 417 e-117 3UJ2-A nrPDB 405 e-113 1W6T-A nrPDB 397 e-111 3ZLH-A nrPDB 397 e-111 6NB2-A nrPDB 396 e-111 3TQP-A nrPDB 384 e-107 6O4N-A nrPDB 380 e-106 6J36-A nrPDB 362 e-100 3QN3-A nrPDB 361 e-100 4MMW-A nrPDB 40 0.002 3R11-A nrPDB 35 0.065 3IK4-A nrPDB 33 0.17 3ERV-A nrPDB 33 0.24 3G68-A nrPDB 32 0.51 1WUE-A nrPDB 32 0.64 4MGG-A nrPDB 31 0.85 3S5S-A nrPDB 30 1.8 1VE5-A nrPDB 30 2.1 5X3E-A nrPDB 30 2.2 5A9Z-CA nrPDB 29 4.7 3GG2-A nrPDB 29 5.1 4HNL-A nrPDB 28 6.1 6ARG-A nrPDB 28 7.2 1TP9-A nrPDB 28 8.0 >2XSX-A nrPDB Length = 435 Score = 879 bits (2272), Expect = 0.0, Method: Compositional matrix adjust. Identities = 425/434 (97%), Positives = 431/434 (99%) Query: 1 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGK 60 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDK RYLGK Sbjct: 2 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGK 61 Query: 61 GVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 120 GVLKAVE+IN TLGPALL+KKLSV DQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK Sbjct: 62 GVLKAVENINSTLGPALLQKKLSVADQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 121 Query: 121 AGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 180 AGAAEKGVPLYRHIADLAGNPDL+LPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE Sbjct: 122 AGAAEKGVPLYRHIADLAGNPDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 181 Query: 181 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV 240 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV Sbjct: 182 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV 241 Query: 241 VIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDD 300 VIGMDVAASEFYRNGKYDLDFKSPDDPARHI+GEKLGELYKSFIKNYPVVSIEDPFDQDD Sbjct: 242 VIGMDVAASEFYRNGKYDLDFKSPDDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDD 301 Query: 301 WATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLA 360 WATWTSFLSGV+IQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLA Sbjct: 302 WATWTSFLSGVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLA 361 Query: 361 QSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDK 420 QSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDK Sbjct: 362 QSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDK 421 Query: 421 AVFAGRKFRNPKAK 434 A+FAGRKFRNPKAK Sbjct: 422 AIFAGRKFRNPKAK 435 >3B97-A nrPDB Length = 433 Score = 761 bits (1966), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/433 (83%), Positives = 397/433 (91%) Query: 2 AMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKG 61 ++ KI AREI DSRGNPTVEVDL T+KG FRAAVPSGASTGIYEALELRD DK+RY+GKG Sbjct: 1 SILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKG 60 Query: 62 VLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKA 121 V KAVEHINKT+ PAL+ KKL+V +QEK+DK MIE+DGTENKSKFGANAILGVSLAVCKA Sbjct: 61 VSKAVEHINKTIAPALVSKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKA 120 Query: 122 GAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEA 181 GA EKGVPLYRHIADLAGN +++LPVPAFNVINGGSHAGNKLAMQEFMILPVGA++F+EA Sbjct: 121 GAVEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFREA 180 Query: 182 MRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVV 241 MRIGAEVYH+LK VIK KYGKDATNVGDEGGFAPNILEN E LELLKTAI AGY DKVV Sbjct: 181 MRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYTDKVV 240 Query: 242 IGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDW 301 IGMDVAASEF+R+GKYDLDFKSPDDP+R+IS ++L +LYKSFIK+YPVVSIEDPFDQDDW Sbjct: 241 IGMDVAASEFFRSGKYDLDFKSPDDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDDW 300 Query: 302 ATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQ 361 W F + IQ+VGDDLTVTNPKRIA+AV +K+CNCLLLKVNQIGSVTES+QACKLAQ Sbjct: 301 GAWQKFTASAGIQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACKLAQ 360 Query: 362 SNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKA 421 +NGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQL+RIEE LG KA Sbjct: 361 ANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSKA 420 Query: 422 VFAGRKFRNPKAK 434 FAGR FRNP AK Sbjct: 421 KFAGRNFRNPLAK 433 >3UJR-A nrPDB Length = 443 Score = 759 bits (1961), Expect = 0.0, Method: Compositional matrix adjust. Identities = 360/430 (83%), Positives = 397/430 (92%) Query: 2 AMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKG 61 +++KI+AREILDSRGNPTVEVDL+TAKG FRAAVPSGASTGIYEALELRDGDK RYLGKG Sbjct: 1 SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKG 60 Query: 62 VLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKA 121 VLKAV+HIN T+ PAL+ LSVV+QEK+D M+ELDGTENKSKFGANAILGVSLAVCKA Sbjct: 61 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 120 Query: 122 GAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEA 181 GAAE+ +PLYRHIA LAGN DL+LPVPAFNVINGGSHAGNKLAMQEFMILPVGA SF++A Sbjct: 121 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 180 Query: 182 MRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVV 241 MR+GAEVYH LKGVIK KYGKDATNVGDEGGFAPNILEN+EALEL+K AI AGY +K+V Sbjct: 181 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIV 240 Query: 242 IGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDW 301 IGMDVAASEFYR+GKYDLDFKSP DP+R+I+G++LG LY+ F+++YPVVSIEDPFDQDDW Sbjct: 241 IGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDW 300 Query: 302 ATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQ 361 A W+ F + V IQIVGDDLTVTNPKRI +AVE+KACNCLLLKVNQIGSVTE+IQACKLAQ Sbjct: 301 AAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQ 360 Query: 362 SNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKA 421 NGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEE LGD+A Sbjct: 361 ENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEA 420 Query: 422 VFAGRKFRNP 431 FAG FRNP Sbjct: 421 RFAGHNFRNP 430 >1PDZ-A nrPDB Length = 434 Score = 647 bits (1669), Expect = 0.0, Method: Compositional matrix adjust. Identities = 309/432 (71%), Positives = 362/432 (83%), Gaps = 2/432 (0%) Query: 2 AMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKG 61 ++ K+FAR I DSRGNPTVEVDL+T+KG FRAAVPSGASTG++EALE+RDGDKS+Y GK Sbjct: 2 SITKVFARTIFDSRGNPTVEVDLYTSKGLFRAAVPSGASTGVHEALEMRDGDKSKYHGKS 61 Query: 62 VLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKA 121 V AV+++N + P +++ L V Q++ D+FM +LDGTENKS GANAILGVSLA+CKA Sbjct: 62 VFNAVKNVNDVIVPEIIKSGLKVTQQKECDEFMCKLDGTENKSSLGANAILGVSLAICKA 121 Query: 122 GAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEA 181 GAAE G+PLYRHIA+LA +++LPVPAFNVINGGSHAGNKLAMQEFMILP GA+SF EA Sbjct: 122 GAAELGIPLYRHIANLANYDEVILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEA 181 Query: 182 MRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVV 241 MR+G EVYHHLK VIKA++G DAT VGDEGGFAPNIL N +AL+L++ AI+ AGY K+ Sbjct: 182 MRMGTEVYHHLKAVIKARFGLDATAVGDEGGFAPNILNNKDALDLIQEAIKKAGYTGKIE 241 Query: 242 IGMDVAASEFYR-NGKYDLDFKSP-DDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQD 299 IGMDVAASEFY+ N YDLDFK+ +D ++ ISG++L ++Y F K++P+VSIEDPFDQD Sbjct: 242 IGMDVAASEFYKQNNIYDLDFKTANNDGSQKISGDQLRDMYMEFCKDFPIVSIEDPFDQD 301 Query: 300 DWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKL 359 DW TW+ SG IQIVGDDLTVTNPKRI AVEKKAC CLLLKVNQIGSVTESI A L Sbjct: 302 DWETWSKMTSGTTIQIVGDDLTVTNPKRITTAVEKKACKCLLLKVNQIGSVTESIDAHLL 361 Query: 360 AQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGD 419 A+ NGWG MVSHRSGETED FIADLVVGLCTGQIKTGAPCRSERLAKYNQ++RIEE LG Sbjct: 362 AKKNGWGTMVSHRSGETEDCFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGS 421 Query: 420 KAVFAGRKFRNP 431 A FAG+ FR P Sbjct: 422 GAKFAGKNFRAP 433 >5WRO-A nrPDB Length = 439 Score = 631 bits (1627), Expect = 0.0, Method: Compositional matrix adjust. Identities = 315/433 (72%), Positives = 360/433 (83%), Gaps = 1/433 (0%) Query: 1 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGK 60 ++ I AR+I DSRGNPTVEVDL T G FRAAVPSGASTG++EALELRD DK+ Y GK Sbjct: 7 FTIKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDNDKANYHGK 66 Query: 61 GVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 120 VLKAV H+N TLGP L++ L VVDQ +D FMI+LDGTENKSKFGANAILGVSLAV K Sbjct: 67 SVLKAVGHVNDTLGPELIKANLDVVDQASIDNFMIKLDGTENKSKFGANAILGVSLAVAK 126 Query: 121 AGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 180 AGAA+KGVPLY+HIADLAGN +++LPVPAFNVINGGSHAGNKLAMQEFMILP GA+SF E Sbjct: 127 AGAAKKGVPLYKHIADLAGNKEIILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTE 186 Query: 181 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV 240 AM++G+EVYHHLK VIKAK+G DAT VGDEGGFAPNI N EAL L+ AI AGY K+ Sbjct: 187 AMKMGSEVYHHLKNVIKAKFGLDATAVGDEGGFAPNIQSNKEALNLISDAIAKAGYTGKI 246 Query: 241 VIGMDVAASEFYRNGKYDLDFKSP-DDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQD 299 IGMDVAASEFY++G+YDLDFK+ D ++ + +KL LY+ FIK++P+VSIEDPFDQD Sbjct: 247 EIGMDVAASEFYKDGQYDLDFKNEKSDKSQWLPADKLANLYQEFIKDFPIVSIEDPFDQD 306 Query: 300 DWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKL 359 W W++ DIQIVGDDLTVTNPKRIA AVEKKACNCLLLKVNQIG+VTESI A L Sbjct: 307 HWEAWSNLTGCTDIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGTVTESIAAHLL 366 Query: 360 AQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGD 419 A+ NGWG MVSHRSGETED+FI DLVVGL TGQIKTGAPCRSERLAKYNQ++RIEE +G Sbjct: 367 AKKNGWGTMVSHRSGETEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEIGA 426 Query: 420 KAVFAGRKFRNPK 432 FAG+ FR P+ Sbjct: 427 GVKFAGKSFRKPQ 439 >3OTR-A nrPDB Length = 452 Score = 564 bits (1454), Expect = e-161, Method: Compositional matrix adjust. Identities = 285/445 (64%), Positives = 347/445 (77%), Gaps = 15/445 (3%) Query: 1 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGK 60 + ++ I AREILDSRGNPT+EVD+ T G FRAAVPSGASTGIYEALELRD D RYLGK Sbjct: 2 VVIKDIVAREILDSRGNPTIEVDVSTEGGVFRAAVPSGASTGIYEALELRDKDPKRYLGK 61 Query: 61 GVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIE-LDGTEN-----KSKFGANAILGV 114 GVL AVE + + + PALL K DQ+ +D M+E LDGT+N KSK GANAILGV Sbjct: 62 GVLNAVEIVRQEIKPALLGK--DPCDQKGIDMLMVEQLDGTKNEWGYSKSKLGANAILGV 119 Query: 115 SLAVCKAGAAEKGVPLYRHIADLAGNP--DLVLPVPAFNVINGGSHAGNKLAMQEFMILP 172 S+A C+AGAA KG+PLY++IA LAG +V+PVP FNVINGG HAGN LA+QEF+I P Sbjct: 120 SIACCRAGAASKGLPLYKYIATLAGKTIDKMVMPVPFFNVINGGEHAGNGLALQEFLIAP 179 Query: 173 VGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQ 232 VGA + +EA+R G+E YHHLK VIK KYG DATNVGDEGGFAPN+ EAL LL AI+ Sbjct: 180 VGAPNIREAIRYGSETYHHLKNVIKNKYGLDATNVGDEGGFAPNVATAEEALNLLVEAIK 239 Query: 233 AAGYPDKVVIGMDVAASEFYRNG--KYDLDFKS-PDDPARHISGEKLGELYKSFIKNYPV 289 AAGY K+ I D AASEFY+ KYDLD+K + ++H++GEKL E+Y+ ++K YP+ Sbjct: 240 AAGYEGKIKIAFDAAASEFYKQDEKKYDLDYKCKTKNASKHLTGEKLKEVYEGWLKKYPI 299 Query: 290 VSIEDPFDQDDWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQI 347 +S+EDPFDQDD+A++++F G Q++GDD+ VTN RI +A++ KACNCLLLKVNQI Sbjct: 300 ISVEDPFDQDDFASFSAFTKDVGEKTQVIGDDILVTNILRIEKALKDKACNCLLLKVNQI 359 Query: 348 GSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKY 407 GSVTE+I+AC LAQ +GWGV VSHRSGETED+FIADLVVGL GQIK+G+PCRSERL KY Sbjct: 360 GSVTEAIEACLLAQKSGWGVQVSHRSGETEDSFIADLVVGLRCGQIKSGSPCRSERLCKY 419 Query: 408 NQLMRIEEALGDKAVFAGRKFRNPK 432 NQLMRIEE+LG V+AG FR+PK Sbjct: 420 NQLMRIEESLGADCVYAGESFRHPK 444 >2XH7-A nrPDB Length = 443 Score = 560 bits (1443), Expect = e-160, Method: Compositional matrix adjust. Identities = 275/430 (63%), Positives = 341/430 (79%), Gaps = 3/430 (0%) Query: 2 AMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKG 61 A+ K++AR + DSRGNPTVEV+L T KG FR+ VPSGASTG++EALE+RDGDKS+++GKG Sbjct: 1 AVSKVYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVHEALEMRDGDKSKWMGKG 60 Query: 62 VLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKA 121 VL AV+++N + PA ++ + V DQ+ VD F+I LDGT NKSK GANAILGVSLA +A Sbjct: 61 VLHAVKNVNDVIAPAFVKANIDVKDQKAVDDFLISLDGTANKSKLGANAILGVSLAASRA 120 Query: 122 GAAEKGVPLYRHIADLAGNPD--LVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFK 179 AAEK VPLY+H+ADL+ + VLPVP NV+NGGSHAG LA+QEFMI P GA +F Sbjct: 121 AAAEKNVPLYKHLADLSKSKTSPYVLPVPFLNVLNGGSHAGGALALQEFMIAPTGAKTFA 180 Query: 180 EAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDK 239 EA+RIG+EVYH+LK + K +YG A NVGDEGG APNI EAL+L+ AI+AAG+ K Sbjct: 181 EALRIGSEVYHNLKSLTKKRYGASAGNVGDEGGVAPNIQTAEEALDLIVDAIKAAGHDGK 240 Query: 240 VVIGMDVAASEFYRNGKYDLDFKSPD-DPARHISGEKLGELYKSFIKNYPVVSIEDPFDQ 298 + IG+D A+SEF+++GKYDLDFK+P+ D ++ ++G +L +LY S +K YP+VSIEDPF + Sbjct: 241 IKIGLDCASSEFFKDGKYDLDFKNPNSDKSKWLTGPQLADLYHSLMKRYPIVSIEDPFAE 300 Query: 299 DDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACK 358 DDW W+ F IQIV D LTVTNPKRIA A+EKKA + LLLKVNQIG+++ESI+A + Sbjct: 301 DDWEAWSHFFKTAGIQIVADALTVTNPKRIATAIEKKAADALLLKVNQIGTLSESIKAAQ 360 Query: 359 LAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALG 418 + + GWGVMVSHRSGETEDTFIADLVVGL TGQIKTGAP RSERLAK NQL+RIEE LG Sbjct: 361 DSFAAGWGVMVSHRSGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEELG 420 Query: 419 DKAVFAGRKF 428 D AVFAG F Sbjct: 421 DNAVFAGENF 430 >3QTP-A nrPDB Length = 441 Score = 550 bits (1416), Expect = e-157, Method: Compositional matrix adjust. Identities = 273/439 (62%), Positives = 337/439 (76%), Gaps = 9/439 (2%) Query: 1 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGK 60 M++QK+ AREILDSRGNPT+EV++ T KG FR+ VPSGASTG++EA+ELRDGDK RY GK Sbjct: 6 MSIQKVHAREILDSRGNPTIEVEITTGKGMFRSCVPSGASTGVHEAVELRDGDKKRYGGK 65 Query: 61 GVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 120 GVLKAVE++N +GPALL K +V++Q ++D+ MI+LDGT NK K GANAILG S+++C+ Sbjct: 66 GVLKAVENVNTIIGPALLGK--NVLNQAELDEMMIKLDGTNNKGKLGANAILGCSMSICR 123 Query: 121 AGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 180 A AAEKG+PLY+++A+L G+ ++ +PVP FNVINGG+HAGN LAMQEFMI P GA++F E Sbjct: 124 AAAAEKGLPLYKYLAELTGHKEMTMPVPCFNVINGGAHAGNALAMQEFMICPTGATNFHE 183 Query: 181 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV 240 A+R+ AE Y LK VIKAKYG+DATNVGDEGGFAPN+ EAL+LL AI AGY K+ Sbjct: 184 ALRMAAETYQCLKVVIKAKYGQDATNVGDEGGFAPNVSGAREALDLLVEAIAKAGYTGKI 243 Query: 241 VIGMDVAASEFY--RNGKYDLDFKSP---DDPARHISGEKLGELYKSFIKNYPVVSIEDP 295 I MD AASEFY KYDL K P DP+ + L Y + K+YP+ SIEDP Sbjct: 244 EIAMDCAASEFYNEETKKYDLGKKIPADKKDPSLVKDVDGLIAEYVDYGKHYPIASIEDP 303 Query: 296 FDQDDWATWTSF-LSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESI 354 F +DDWA W F + + QIVGDDL VTNP R+ A++K ACN +L+KVNQIG++TE+ Sbjct: 304 FAEDDWAAWNKFTVEHGNFQIVGDDLLVTNPARVQMAMDKNACNSVLIKVNQIGTLTETF 363 Query: 355 QACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIE 414 + K+AQ GWGVM SHRSGETEDTFIADLVVGL QIKTGAPCRSERL KYNQLMRIE Sbjct: 364 KTIKMAQEKGWGVMASHRSGETEDTFIADLVVGLNCKQIKTGAPCRSERLCKYNQLMRIE 423 Query: 415 EALGDKAVFAGRKFRNPKA 433 E LG+ +AG+ +RN A Sbjct: 424 EELGN-IPYAGKNWRNSTA 441 >4G7F-A nrPDB Length = 429 Score = 526 bits (1356), Expect = e-150, Method: Compositional matrix adjust. Identities = 270/428 (63%), Positives = 320/428 (74%), Gaps = 10/428 (2%) Query: 1 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGK 60 M +QK+ REILDSRGNPTVEV++ T G FR+AVPSGASTGI+EA ELRD DK RYLGK Sbjct: 1 MTIQKVHGREILDSRGNPTVEVEVTTELGVFRSAVPSGASTGIHEACELRDDDKRRYLGK 60 Query: 61 GVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 120 G L AV+++N L PAL+ K + Q +DK M +LDGT NKSK GANAILG S+A+ K Sbjct: 61 GCLNAVKNVNDVLAPALVGK--DELQQSTLDKLMRDLDGTPNKSKLGANAILGCSMAISK 118 Query: 121 AGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 180 A AA KGVPLYR++A+LAG ++ LPVP FNVINGG HAGN L QEFMI PV A SF E Sbjct: 119 AAAARKGVPLYRYLAELAGTKEVRLPVPCFNVINGGKHAGNALPFQEFMIAPVKAGSFNE 178 Query: 181 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV 240 A+R+GAEVYH LK +IK KYG+DA NVGDEGGFAP I + NE L +L AI+ AG+ + Sbjct: 179 ALRMGAEVYHSLKSIIKKKYGQDAVNVGDEGGFAPPITDINEPLPILMEAIEQAGHKGRF 238 Query: 241 VIGMDVAASEFYRNGK--YDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQ 298 I MD AASE Y K Y+L FKSP+ A ++ ++L E Y ++ YP+VS+EDP+DQ Sbjct: 239 AICMDSAASETYDENKKQYNLTFKSPE--ATWVTAKQLAETYAKWVSEYPIVSLEDPYDQ 296 Query: 299 DD---WATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQ 355 DD +A T L G Q+VGDDLTVTN RI A+EKKACN LLLK+NQIG++TE+I+ Sbjct: 297 DDFDGFAGITEALKG-KAQVVGDDLTVTNVSRIKTAIEKKACNSLLLKINQIGTITEAIE 355 Query: 356 ACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEE 415 A K SNGW VMVSHRSGETEDT+IADLVVGL TGQIKTGAPCR ER AK NQL+RIEE Sbjct: 356 ASKFCMSNGWSVMVSHRSGETEDTYIADLVVGLGTGQIKTGAPCRGERTAKLNQLLRIEE 415 Query: 416 ALGDKAVF 423 LG A F Sbjct: 416 ELGAHAKF 423 >2PU1-A nrPDB Length = 432 Score = 519 bits (1336), Expect = e-147, Method: Compositional matrix adjust. Identities = 263/427 (61%), Positives = 324/427 (75%), Gaps = 8/427 (1%) Query: 1 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGK 60 M +QK+ RE+LDSRGNPTVEV++ T KG FR+AVPSGASTG+YEA ELRDGDK RY+GK Sbjct: 4 MTIQKVHGREVLDSRGNPTVEVEVTTEKGVFRSAVPSGASTGVYEACELRDGDKKRYVGK 63 Query: 61 GVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 120 G L+AV+++N+ +GPAL+ + + QE++D M+ LDGT NK K GANAILG S+A+ K Sbjct: 64 GCLQAVKNVNEVIGPALIGR--DELKQEELDTLMLRLDGTPNKGKLGANAILGCSMAISK 121 Query: 121 AGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 180 A AA KGVPLYR++A LAG +L LPVP FNVINGG HAGN L QEFMI PV A+SF E Sbjct: 122 AAAAAKGVPLYRYLASLAGTKELRLPVPCFNVINGGKHAGNALPFQEFMIAPVKATSFSE 181 Query: 181 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV 240 A+R+G+EVYH L+G+IK KYG+DA NVGDEGGFAP I + NE L +L AI+ AG+ K Sbjct: 182 ALRMGSEVYHSLRGIIKKKYGQDAVNVGDEGGFAPPIKDINEPLPILMEAIEEAGHRGKF 241 Query: 241 VIGMDVAASEFY--RNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQ 298 I MD AASE Y + +Y+L FKSP+ ++ E+L E Y + +YP+VSIEDP+DQ Sbjct: 242 AICMDCAASETYDEKKQQYNLTFKSPE--PTWVTAEQLRETYCKWAHDYPIVSIEDPYDQ 299 Query: 299 DDWATWTSFLSGV--DIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQA 356 DD+A + + QIVGDDLTVTN +RI A+EKKACN LLLK+NQIG+++E+I + Sbjct: 300 DDFAGFAGITEALKGKTQIVGDDLTVTNTERIKMAIEKKACNSLLLKINQIGTISEAIAS 359 Query: 357 CKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEA 416 KL NGW VMVSHRSGETEDT+IADLVV L +GQIKTGAPCR ER AK NQL+RIEE Sbjct: 360 SKLCMENGWSVMVSHRSGETEDTYIADLVVALGSGQIKTGAPCRGERTAKLNQLLRIEEE 419 Query: 417 LGDKAVF 423 LG A F Sbjct: 420 LGAHAKF 426 >2PA6-A nrPDB Length = 427 Score = 446 bits (1147), Expect = e-126, Method: Compositional matrix adjust. Identities = 242/430 (56%), Positives = 312/430 (72%), Gaps = 15/430 (3%) Query: 3 MQKIFAREILDSRGNPTVEVDLHT-AKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKG 61 ++ I ARE++DSRGNPTVEV++ T G A VPSGASTG +EALELRD +K R+ GKG Sbjct: 11 IKDIVAREVIDSRGNPTVEVEVITKGNGYGSAIVPSGASTGTHEALELRDKEK-RFGGKG 69 Query: 62 VLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKA 121 VL AVE++N + P +L + Q ++D MIELDGT NKS+ GANAIL VSLAV KA Sbjct: 70 VLMAVENVNSIIRPEILGYDARM--QREIDTIMIELDGTPNKSRLGANAILAVSLAVAKA 127 Query: 122 GAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEA 181 AA +PLY++ L G V+PVP NVINGG HAGN L +QEFMI+PVGA+S EA Sbjct: 128 AAATAKIPLYKY---LGGFNSYVMPVPMMNVINGGKHAGNDLDLQEFMIMPVGATSISEA 184 Query: 182 MRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVV 241 +R+G+EVYH LK VI KYGK+A NVGDEGGFAP + + EAL+LL +++ AGY D+VV Sbjct: 185 VRMGSEVYHVLKNVILEKYGKNAVNVGDEGGFAPPLKTSREALDLLTESVKKAGYEDEVV 244 Query: 242 IGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDW 301 +D AASEFY++G Y ++ + ++ E+L + YK+ + YP+VSIEDPF ++D+ Sbjct: 245 FALDAAASEFYKDGYYYVE-------GKKLTREELLDYYKALVDEYPIVSIEDPFHEEDF 297 Query: 302 ATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQ 361 + +DIQIVGDDL VTN +R+ + +E KA N LLLKVNQIG+++E++ A +LA Sbjct: 298 EGFAMITKELDIQIVGDDLFVTNVERLRKGIEMKAANALLLKVNQIGTLSEAVDAAQLAF 357 Query: 362 SNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKA 421 NG+GV+VSHRSGETEDT IADL V L +GQIKTGAP R ER AKYNQL+RIE+ LG + Sbjct: 358 RNGYGVVVSHRSGETEDTTIADLSVALNSGQIKTGAPARGERTAKYNQLIRIEQELG-LS 416 Query: 422 VFAGRKFRNP 431 +AGR FR P Sbjct: 417 KYAGRNFRCP 426 >6BFZ-A nrPDB Length = 449 Score = 436 bits (1120), Expect = e-122, Method: Compositional matrix adjust. Identities = 238/429 (55%), Positives = 300/429 (69%), Gaps = 14/429 (3%) Query: 5 KIFAREILDSRGNPTVEVDLHTAKGRF-RAAVPSGASTGIYEALELRDGDKSRYLGKGVL 63 KI REI+DSRGNPTVE ++H G AA PSGASTG EALELRDGDKSR+LGKGV Sbjct: 23 KIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVT 82 Query: 64 KAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGA 123 KAV +N + AL+ K DQ +DK MI+LDGTENKSKFGANAIL VSLA KA A Sbjct: 83 KAVAAVNGPIAQALIGKDAK--DQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAA 140 Query: 124 AEKGVPLYRHIADLAGNP-DLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAM 182 A KG+PLY HIA+L G P +PVP N+INGG HA N + +QEFMI PVGA + KEA+ Sbjct: 141 AAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAI 200 Query: 183 RIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DKV 240 R+G+EV+HHL V+KAK G + T VGDEGG+APN+ N EAL ++ A++AAGY + Sbjct: 201 RMGSEVFHHLAKVLKAK-GMN-TAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDI 258 Query: 241 VIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDD 300 + MD AASEFY++GKY L + + + E+ + K YP+VSIED D+ D Sbjct: 259 TLAMDCAASEFYKDGKYVL----AGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESD 314 Query: 301 WA--TWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACK 358 W + + + G IQ+VGDDL VTN K + + +EK N +L+K NQIGS+TE++ A K Sbjct: 315 WDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIK 374 Query: 359 LAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALG 418 +A+ G+ ++SHRSGETED IADL VG GQIKTG+ RS+R+AKYNQL+RIEEALG Sbjct: 375 MAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALG 434 Query: 419 DKAVFAGRK 427 +KA + GRK Sbjct: 435 EKAPYNGRK 443 >5BOE-A nrPDB Length = 442 Score = 427 bits (1098), Expect = e-120, Method: Compositional matrix adjust. Identities = 221/434 (50%), Positives = 303/434 (69%), Gaps = 12/434 (2%) Query: 3 MQKIFAREILDSRGNPTVEVDLHTAKGRF-RAAVPSGASTGIYEALELRDGDKSRYLGKG 61 + ++ARE+LDSRGNPTVEV++ T G F RA VPSGASTG +EA+ELRDGDKSRYLGKG Sbjct: 4 ITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASTGEHEAVELRDGDKSRYLGKG 63 Query: 62 VLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKA 121 V KAVE++N+ + P ++E + SV+DQ +DK MI LDGT NK K GANAILGVS+AV +A Sbjct: 64 VTKAVENVNEIIAPEIIEGEFSVLDQVSIDKMMIALDGTPNKGKLGANAILGVSIAVARA 123 Query: 122 GAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEA 181 A G PLY+++ G LPVP N++NGGSH+ +A QEFMILPVGA++FKE+ Sbjct: 124 AADLLGQPLYKYLGGFNGKQ---LPVPMMNIVNGGSHSDAPIAFQEFMILPVGATTFKES 180 Query: 182 MRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DK 239 +R G E++H+LK ++ +K G + T VGDEGGFAP +A+E + AI+AAGY ++ Sbjct: 181 LRWGTEIFHNLKSIL-SKRGLE-TAVGDEGGFAPKFEGTEDAVETIIQAIEAAGYKPGEE 238 Query: 240 VVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQD 299 V +G D A+SEFY NG YD + A+ + E++ L + + YP+++IED D++ Sbjct: 239 VFLGFDCASSEFYENGVYDYSKFEGEHGAKRTAAEQVDYL-EQLVDKYPIITIEDGMDEN 297 Query: 300 DWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQAC 357 DW W G +Q+VGDDL VTN + +A+ +E N +L+KVNQIG++TE+ A Sbjct: 298 DWDGWKQLTERIGDRVQLVGDDLFVTNTEILAKGIENGIGNSILIKVNQIGTLTETFDAI 357 Query: 358 KLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEAL 417 ++AQ G+ +VSHRSGETEDT IAD+ V GQIKTG+ R++R+AKYNQL+RIE+ L Sbjct: 358 EMAQKAGYTAVVSHRSGETEDTTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDEL 417 Query: 418 GDKAVFAG-RKFRN 430 + A + G + F N Sbjct: 418 FETAKYDGIKSFYN 431 >5J04-A nrPDB Length = 425 Score = 426 bits (1096), Expect = e-120, Method: Compositional matrix adjust. Identities = 235/435 (54%), Positives = 294/435 (67%), Gaps = 20/435 (4%) Query: 3 MQKIFAREILDSRGNPTVEVDLHTAKGRF-RAAVPSGASTGIYEALELRDGDKSRYLGKG 61 + +I AREILDSRG PTVE ++H G A VPSGASTG +EA ELRD D SRY GKG Sbjct: 5 IAEITAREILDSRGRPTVEAEVHLEDGSVGLAQVPSGASTGTFEAHELRDDDPSRYGGKG 64 Query: 62 VLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKA 121 V KAVE+++ + AL+ LS +DQE +DK MI LDGT NK GANAIL VSLA A Sbjct: 65 VQKAVENVS-AIEDALI--GLSALDQEGLDKAMIALDGTPNKKNLGANAILAVSLATAHA 121 Query: 122 GAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEA 181 A +PLYR++ N VLPVP NVINGG+HA N + QEFMI+PVGA SFKEA Sbjct: 122 AATSLNLPLYRYLGGPLAN---VLPVPMMNVINGGAHADNNVDFQEFMIMPVGAPSFKEA 178 Query: 182 MRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DK 239 +R GAEV+H L V+K K AT VGDEGGFAPN+ N EALELL TAI+AAGY ++ Sbjct: 179 LRWGAEVFHALAKVLKDK--GLATGVGDEGGFAPNLGSNKEALELLLTAIEAAGYKPGEQ 236 Query: 240 VVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQD 299 V + MDVA+SEFY+NG Y D S +PA I + + YP+VSIED +D Sbjct: 237 VALAMDVASSEFYKNGLYTCDGVS-HEPAGMIG------ILADLVSQYPIVSIEDGLQED 289 Query: 300 DWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQAC 357 DW+ W + G +Q+VGDDL VTNP R+ +E+ N +L+K+NQIG++TE+++ Sbjct: 290 DWSNWKTLTQQLGSTVQLVGDDLFVTNPDRLQSGIEQGVGNAVLIKLNQIGTLTETLRTI 349 Query: 358 KLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEAL 417 LA +G+ ++SHRSGETEDT IADL V GQIKTG+ RSER+AKYN+L+RIE AL Sbjct: 350 DLATRSGYRSVISHRSGETEDTTIADLAVATRAGQIKTGSLSRSERIAKYNRLLRIEAAL 409 Query: 418 GDKAVFAGRKFRNPK 432 G+ A++AG PK Sbjct: 410 GENALYAGAIGLGPK 424 >4Z1Y-A nrPDB Length = 426 Score = 426 bits (1095), Expect = e-119, Method: Compositional matrix adjust. Identities = 225/429 (52%), Positives = 298/429 (69%), Gaps = 17/429 (3%) Query: 3 MQKIFAREILDSRGNPTVEVDLHTAKGRF-RAAVPSGASTGIYEALELRDGDKSRYLGKG 61 ++ I ARE+LDSRGNPT+EVD+ G RA VPSGASTG +EALELRDGDKSRY GKG Sbjct: 5 IEAIVAREVLDSRGNPTIEVDVRLESGDVGRAIVPSGASTGAHEALELRDGDKSRYNGKG 64 Query: 62 VLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKA 121 VLKAV+ +N+ + AL+ DQ +D+ +I LDGT NKSK GANAILGVSLA KA Sbjct: 65 VLKAVQAVNEDIAEALI--GFDAADQIALDQELIALDGTPNKSKLGANAILGVSLAAAKA 122 Query: 122 GAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEA 181 AA G+PLYR++ + + VLPVP N++NGG HA N QEFMI+PVGA SF+E Sbjct: 123 AAAAFGLPLYRYLGGVYAH---VLPVPMMNIMNGGQHATNSTDFQEFMIMPVGAESFREG 179 Query: 182 MRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DK 239 +R GAE+YH LK VI + +T VGDEGGFAP++ N+ L+L+ AI+ AGY ++ Sbjct: 180 LRWGAEIYHMLKKVIHDR--GFSTTVGDEGGFAPSLPTNDAPLQLIMEAIEKAGYRPGEQ 237 Query: 240 VVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQD 299 +VI +D A +E + +GKY L + R +S ++ + + + YP++S+ED +D Sbjct: 238 IVIALDPATTEIFEDGKYHLKRE-----GRSLSSAEMVDYWVDLVNRYPIISLEDGLAED 292 Query: 300 DWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQAC 357 DW W + G +Q+VGDD VTN +R+ +A+E KA N +L+K+NQIGS+TE++ A Sbjct: 293 DWEGWALLRAKLGDRVQLVGDDFLVTNVQRLQRAIEAKAANSILIKLNQIGSLTETLSAI 352 Query: 358 KLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEAL 417 +LAQ +GW +VSHRSGE+ED IADLVV GQIKTGAP R++R+AKYNQL+RIEE L Sbjct: 353 QLAQRSGWTAVVSHRSGESEDVTIADLVVATNAGQIKTGAPARTDRIAKYNQLLRIEEEL 412 Query: 418 GDKAVFAGR 426 G A +AGR Sbjct: 413 GSAARYAGR 421 >1IYX-A nrPDB Length = 432 Score = 419 bits (1076), Expect = e-117, Method: Compositional matrix adjust. Identities = 223/439 (50%), Positives = 302/439 (68%), Gaps = 19/439 (4%) Query: 3 MQKIFAREILDSRGNPTVEVDLHTAKGRF-RAAVPSGASTGIYEALELRDGDKSRYLGKG 61 + ++AREILDSRGNPT+EV+++T G F R VPSGASTG YEA+ELRDGDK+RY GKG Sbjct: 4 ITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTGEYEAVELRDGDKARYGGKG 63 Query: 62 VLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKA 121 V KAV+++N + A++ V DQ +DK MI LDGT NK K GANAILGVS+AV +A Sbjct: 64 VTKAVDNVNNIIAEAII--GYDVRDQMAIDKAMIALDGTPNKGKLGANAILGVSIAVARA 121 Query: 122 GAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEA 181 A VPLY + L G VLP P N+INGGSHA N + QEFMI+PVGA +FKEA Sbjct: 122 AADYLEVPLYHY---LGGFNTKVLPTPMMNIINGGSHADNSIDFQEFMIMPVGAPTFKEA 178 Query: 182 MRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGY-PDK- 239 +R+GAEV+H L ++K++ AT+VGDEGGFAPN+ N E E++ AI+ AGY P K Sbjct: 179 LRMGAEVFHALAAILKSR--GLATSVGDEGGFAPNLGSNEEGFEVIIEAIEKAGYVPGKD 236 Query: 240 VVIGMDVAASEFY--RNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFD 297 VV+ MD A+SEFY G Y L D + +++ + Y+ + YP++SIED D Sbjct: 237 VVLAMDAASSEFYDKEKGVYVL----ADSGEGEKTTDEMIKFYEELVSKYPIISIEDGLD 292 Query: 298 QDDWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQ 355 ++DW + G +Q+VGDDL VTN +++++ +EK N +L+KVNQIG++TE+ + Sbjct: 293 ENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIANSILIKVNQIGTLTETFE 352 Query: 356 ACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEE 415 A ++A+ G+ +VSHRSGETED+ I+D+ V GQIKTG+ R++R+AKYNQL+RIE+ Sbjct: 353 AIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKTGSLSRTDRIAKYNQLLRIED 412 Query: 416 ALGDKAVFAGRK-FRNPKA 433 LG+ A + G K F N KA Sbjct: 413 QLGEVAEYKGLKSFYNLKA 431 >4MKS-A nrPDB Length = 440 Score = 417 bits (1072), Expect = e-117, Method: Compositional matrix adjust. Identities = 221/429 (51%), Positives = 292/429 (68%), Gaps = 17/429 (3%) Query: 3 MQKIFAREILDSRGNPTVEVDLHTAKGRF-RAAVPSGASTGIYEALELRDGDKSRYLGKG 61 + I ARE+LDSRGNPT E +++T G F RA VPSGASTG +EA+ELRDGDKSR+ G+G Sbjct: 4 ITDIHAREVLDSRGNPTAEAEVYTELGGFGRAIVPSGASTGEHEAVELRDGDKSRFGGQG 63 Query: 62 VLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKA 121 VL AVE++N + A++ L V DQ +D+ MI+LDGT NK + GANAIL VSLA +A Sbjct: 64 VLTAVENVNGEIAKAVI--GLDVTDQRLIDQTMIDLDGTPNKGRLGANAILSVSLASARA 121 Query: 122 GAAEKGVPLYRHIADLAGNPDL-VLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 180 A E G+PLY ++ G P+ VLP P NVINGG HA N + +QEFMI+PVGA S E Sbjct: 122 AADELGLPLYEYL----GGPNAHVLPTPMMNVINGGKHADNNVDIQEFMIMPVGAKSLHE 177 Query: 181 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--D 238 A+R+GAE +H LKG+++ + ++T VGDEGGFAPN+ N E E+L AIQ AGY Sbjct: 178 AVRMGAETFHTLKGLLQER--GESTAVGDEGGFAPNLKNNEEPFEILVEAIQRAGYKPGQ 235 Query: 239 KVVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQ 298 + I D AASEFY K + + D R + E+ L + + YPV+S+EDP D+ Sbjct: 236 DIAIAFDCAASEFYN--KDTKKYVTVAD-GREYTAEEWTSLIEDLVDKYPVISVEDPLDE 292 Query: 299 DDWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQA 356 +DW W +F G +QIVGDDL VTN + + ++ N +L+K+NQIG++TE+ +A Sbjct: 293 NDWEGWKTFTERLGDKVQIVGDDLFVTNTSYLEKGIKMGVANSILIKLNQIGTLTETFEA 352 Query: 357 CKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEA 416 ++A+ G+ +VSHRSGETEDT IADLVV GQIKTG+ R++R+AKYNQLMRIEEA Sbjct: 353 IEMAKEAGYTAVVSHRSGETEDTTIADLVVATNAGQIKTGSMSRTDRIAKYNQLMRIEEA 412 Query: 417 LGDKAVFAG 425 LG A + G Sbjct: 413 LGSTAQYKG 421 >4A3R-A nrPDB Length = 430 Score = 417 bits (1071), Expect = e-117, Method: Compositional matrix adjust. Identities = 217/434 (50%), Positives = 299/434 (68%), Gaps = 33/434 (7%) Query: 6 IFAREILDSRGNPTVEVDLHTAKGRF-RAAVPSGASTGIYEALELRDGDKSRYLGKGVLK 64 ++ARE+LDSRGNPTVEV+++T G F RA VPSGASTG YEA+ELRDGDK RYLGKGVL Sbjct: 7 VYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGEYEAVELRDGDKDRYLGKGVLT 66 Query: 65 AVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAA 124 AV ++N+ + P LL V +Q +D+ +IELDGTENK K GANAILGVS+A +A A Sbjct: 67 AVNNVNEIIAPELL--GFDVTEQNAIDQLLIELDGTENKGKLGANAILGVSMACARAAAD 124 Query: 125 EKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRI 184 +PLY++ L G LPVP N++NGG HA N + +QEFMI+PVGA +F+EA+R+ Sbjct: 125 FLQIPLYQY---LGGFNSKTLPVPMMNIVNGGEHADNNVDIQEFMIMPVGAPNFREALRM 181 Query: 185 GAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DKVVI 242 GA+++H LK V+ AK G + T VGDEGGFAPN+ N EAL+ + AI+ AG+ ++V + Sbjct: 182 GAQIFHSLKSVLSAK-GLN-TAVGDEGGFAPNLGSNEEALQTIVEAIEKAGFKPGEEVKL 239 Query: 243 GMDVAASEFY--RNGKYDLDFKSPDDPARHISGE-------KLGELYKSFIKNYPVVSIE 293 MD A+SEFY +GKY H+SGE ++ + Y+ + YP++SIE Sbjct: 240 AMDAASSEFYNKEDGKY------------HLSGEGVVKTSAEMVDWYEELVSKYPIISIE 287 Query: 294 DPFDQDDWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVT 351 D D++DW G +Q+VGDDL VTN K++++ ++ N +L+KVNQIG++T Sbjct: 288 DGLDENDWEGHKLLTERLGKKVQLVGDDLFVTNTKKLSEGIKNGVGNSILIKVNQIGTLT 347 Query: 352 ESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLM 411 E+ A ++A+ G+ ++SHRSGETED+ IAD+ V GQIKTGAP R++R+AKYNQL+ Sbjct: 348 ETFDAIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRVAKYNQLL 407 Query: 412 RIEEALGDKAVFAG 425 RIE+ L + A + G Sbjct: 408 RIEDQLAETAQYHG 421 >3UJ2-A nrPDB Length = 449 Score = 405 bits (1040), Expect = e-113, Method: Compositional matrix adjust. Identities = 223/432 (51%), Positives = 299/432 (69%), Gaps = 19/432 (4%) Query: 1 MAMQKIFAREILDSRGNPTVEVDLHTAKG-RFRAAVPSGASTGIYEALELRDGDKSRYLG 59 + ++K+ REI+DSRGNPTVE +++ A G R PSGASTG +EALELRDGDK R+ G Sbjct: 26 LEIEKVIGREIIDSRGNPTVEAEVYLAGGVTGRGTAPSGASTGEFEALELRDGDKGRFGG 85 Query: 60 KGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVC 119 KGV KAV++IN + L + D VD+ MI+ DGT++KSKFGANA+L VS+A Sbjct: 86 KGVTKAVQNINTEISEIL--SGMDASDIYAVDRAMIDADGTKDKSKFGANAVLAVSIACA 143 Query: 120 KAGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFK 179 KA AA GVPLYR + L N LPVP N++NGG+HA N + +QEFMI+PVGA SF+ Sbjct: 144 KAAAAALGVPLYRFLGGLNANR---LPVPMMNILNGGAHAANTVDVQEFMIMPVGAESFR 200 Query: 180 EAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGY-PD 238 EA+R EV+H L G++K+K AT+VGDEGGFAP++ + EA+E + A++ AGY P Sbjct: 201 EALRQCTEVFHALAGLLKSK--GLATSVGDEGGFAPDLASDEEAIEYILEAVKLAGYEPG 258 Query: 239 K-VVIGMDVAASEF--YRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDP 295 + V+ MD A+SE+ + G+Y L R + E+L +KS + YP+VSIED Sbjct: 259 RDFVLAMDAASSEWKGEKKGEYILP-----KCKRKFASEELVAHWKSLCERYPIVSIEDG 313 Query: 296 FDQDDWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTES 353 D++DW W G IQ+VGDDL VTN +R+ + ++++ N +L+K+NQIG+V+E+ Sbjct: 314 LDEEDWEGWQYMTRELGDKIQLVGDDLFVTNTERLNKGIKERCGNSILIKLNQIGTVSET 373 Query: 354 IQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRI 413 ++A K+A G+ +VSHRSGETEDT IADL V L TGQIKTGAP RSER+AKYNQL+RI Sbjct: 374 LEAIKMAHKAGYTAVVSHRSGETEDTTIADLAVALNTGQIKTGAPSRSERVAKYNQLLRI 433 Query: 414 EEALGDKAVFAG 425 EE LGD AV+ G Sbjct: 434 EEELGDSAVYPG 445 >1W6T-A nrPDB Length = 444 Score = 397 bits (1021), Expect = e-111, Method: Compositional matrix adjust. Identities = 215/438 (49%), Positives = 296/438 (67%), Gaps = 16/438 (3%) Query: 3 MQKIFAREILDSRGNPTVEVDLHTAKGRF-RAAVPSGASTGIYEALELRDGDKSRYLGKG 61 + ++ARE+LDSRGNPT+EV+++T G F R VPSGASTG +EA+ELRDGDKSRY G G Sbjct: 14 ITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYGGLG 73 Query: 62 VLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKA 121 KAV+++N + A++ V DQ+ +D+ MI LDGT NK K GANAILGVS+AV +A Sbjct: 74 TQKAVDNVNNIIAEAII--GYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARA 131 Query: 122 GAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEA 181 A +PLY + L G VLP P N+INGGSH+ +A QEFMILPVGA +FKEA Sbjct: 132 AADYLEIPLYSY---LGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMILPVGAPTFKEA 188 Query: 182 MRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGY-PDK- 239 +R GAE++H LK ++K++ G + T VGDEGGFAP + +E + AI+AAGY P K Sbjct: 189 LRYGAEIFHALKKILKSR-GLE-TAVGDEGGFAPRFEGTEDGVETILAAIEAAGYVPGKD 246 Query: 240 VVIGMDVAASEFYRNGK--YDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFD 297 V +G D A+SEFY + YD + A S E++ L + + YP+++IED D Sbjct: 247 VFLGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQIDYL-EELVNKYPIITIEDGMD 305 Query: 298 QDDWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQ 355 ++DW W + G +Q+VGDD VTN +A+ +++ A N +L+KVNQIG++TE+ + Sbjct: 306 ENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQEGAANSILIKVNQIGTLTETFE 365 Query: 356 ACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEE 415 A ++A+ G+ +VSHRSGETED+ IAD+ V GQIKTG+ R++R+AKYNQL+RIE+ Sbjct: 366 AIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIED 425 Query: 416 ALGDKAVFAGRK-FRNPK 432 LG+ A + G K F N K Sbjct: 426 QLGEVAEYRGLKSFYNLK 443 >3ZLH-A nrPDB Length = 455 Score = 397 bits (1019), Expect = e-111, Method: Compositional matrix adjust. Identities = 212/439 (48%), Positives = 293/439 (66%), Gaps = 17/439 (3%) Query: 3 MQKIFAREILDSRGNPTVEVDLHTAKGRF-RAAVPSGASTGIYEALELRDGDKSRYLGKG 61 + ++ARE+LDSRGNPT+EV+++T G F R VPSGASTG +EA+ELRDGDKSRYLG G Sbjct: 24 ITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYLGLG 83 Query: 62 VLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKA 121 KAV+++N + A++ V DQ+ +D+ MI LDGT NK K GANAILGVS+AV +A Sbjct: 84 TQKAVDNVNNIIAKAII--GYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARA 141 Query: 122 GAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEA 181 A VPLY + L G VLP P N+INGGSH+ +A QEFMI+PVGA +FKE Sbjct: 142 AADYLEVPLYTY---LGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMIMPVGAPTFKEG 198 Query: 182 MRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP---D 238 +R GAEV+H LK ++K + T VGDEGGFAP + +E + AI+AAGY + Sbjct: 199 LRWGAEVFHALKKILKER--GLVTAVGDEGGFAPKFEGTEDGVETILKAIEAAGYEAGEN 256 Query: 239 KVVIGMDVAASEFYRNGK--YDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPF 296 ++IG D A+SEFY + YD + A S E++ L + + YP+++IED Sbjct: 257 GIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQVDYL-EELVNKYPIITIEDGM 315 Query: 297 DQDDWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESI 354 D++DW W G +Q+VGDD VTN + +A+ +++ A N +L+KVNQIG++TE+ Sbjct: 316 DENDWDGWKVLTERLGKRVQLVGDDFFVTNTEYLARGIKENAANSILIKVNQIGTLTETF 375 Query: 355 QACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIE 414 +A ++A+ G+ +VSHRSGETED+ IAD+ V GQIKTG+ R++R+AKYNQL+RIE Sbjct: 376 EAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIE 435 Query: 415 EALGDKAVFAG-RKFRNPK 432 + LG+ A + G + F N K Sbjct: 436 DQLGEVAQYKGIKSFYNLK 454 >6NB2-A nrPDB Length = 430 Score = 396 bits (1018), Expect = e-111, Method: Compositional matrix adjust. Identities = 212/416 (50%), Positives = 278/416 (66%), Gaps = 17/416 (4%) Query: 5 KIFAREILDSRGNPTVEVDLHTAKGRF-RAAVPSGASTGIYEALELRDGDKSRYLGKGVL 63 KI AREILDSRGNPT+E D+ G RA+VPSGASTG EA ELRD D RY GKGV Sbjct: 13 KIQAREILDSRGNPTIEADVTLTTGIIGRASVPSGASTGSREACELRDNDPKRYAGKGVQ 72 Query: 64 KAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGA 123 KAV+H+N + AL + LSV DQE +D+ + +LD TENKS GANAIL SLA +A A Sbjct: 73 KAVKHVNNEINQAL--QGLSVEDQENLDRILCQLDNTENKSHLGANAILATSLACARARA 130 Query: 124 AEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMR 183 PLY L + +PVP N++NGG+HA N + +QEFMI+P+GA F A++ Sbjct: 131 LSLNQPLY---MTLNQGDMMTMPVPMMNILNGGAHADNNVDIQEFMIMPIGAPDFPVALQ 187 Query: 184 IGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DKVV 241 +G E++H LK V+K K G + T VGDEGGFAPNI N +AL+LL AI+ AG+ + +V Sbjct: 188 MGTEIFHVLKSVLK-KQGLN-TAVGDEGGFAPNIQSNRQALDLLSEAIEKAGFRLGEDIV 245 Query: 242 IGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDW 301 +DVAASE + G Y + ++ + +L E Y + I +YP+VSIED D+ DW Sbjct: 246 FALDVAASELFNEGFYHMYSEN-----QKFDSHQLIEYYANLISSYPIVSIEDGLDEKDW 300 Query: 302 ATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKL 359 + W + G +Q+VGDDL VTNPK + + + + N +L+KVNQIG+++E+ QA KL Sbjct: 301 SGWKQLTTHLGNKVQLVGDDLFVTNPKILREGIAQGIANAILIKVNQIGTLSETRQAIKL 360 Query: 360 AQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEE 415 A NG+ ++SHRSGETEDTFIADL V GQIKTG+ CR++R AKYNQL+RI E Sbjct: 361 AYDNGYRCVMSHRSGETEDTFIADLAVASGCGQIKTGSLCRTDRTAKYNQLLRINE 416 >3TQP-A nrPDB Length = 428 Score = 384 bits (985), Expect = e-107, Method: Compositional matrix adjust. Identities = 211/430 (49%), Positives = 289/430 (67%), Gaps = 18/430 (4%) Query: 3 MQKIFAREILDSRGNPTVEVDLHTAKGRFR-AAVPSGASTGIYEALELRDGDKSRYLGKG 61 + I A EILDSR NPT+EV + + + AAVPSGASTG EA+ELRD D RY GKG Sbjct: 5 ITDINAHEILDSRANPTLEVRVTLSSQAYGCAAVPSGASTGEREAVELRDNDLERYGGKG 64 Query: 62 VLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKA 121 VL+AVE++N + ALL + QE++D+ MIELDGTENK+ GANAILGVSLAV A Sbjct: 65 VLQAVENVNGPIRDALLGQDPR--SQEEIDRIMIELDGTENKANLGANAILGVSLAVAYA 122 Query: 122 GAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEA 181 A +PLYR++ G +PVP N+INGG+HA N L QEFMI+PVGA +F EA Sbjct: 123 AANNADLPLYRYLGGDGG--PFSMPVPMMNIINGGAHATNNLDFQEFMIVPVGAPTFAEA 180 Query: 182 MRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGY-PDK- 239 +R GAEV+H LK + ++ A VGDEGGFAP++ N A EL+ AI+ A Y P K Sbjct: 181 LRYGAEVFHALKKRLVSRGLMSA--VGDEGGFAPDLPNNEAAFELILEAIEDANYVPGKD 238 Query: 240 VVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQD 299 + + +D A+SE Y+NG+YD + ++ E++ + + K YPV+SIED ++ Sbjct: 239 IYLALDAASSELYQNGRYDFE-------NNQLTSEEMIDRLTEWTKKYPVISIEDGLSEN 291 Query: 300 DWATWTSFLSGVD--IQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQAC 357 DWA W ++ +Q+VGDD+ VTNP + + ++K N +L+K+NQIG++TE++ Sbjct: 292 DWAGWKLLTERLENKVQLVGDDIFVTNPDILEKGIKKNIANAILVKLNQIGTLTETLATV 351 Query: 358 KLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEAL 417 LA+SN +GV++SHRSGETEDT IADL V QIKTG+ CRS+R+AKYN+L++IE L Sbjct: 352 GLAKSNKYGVIISHRSGETEDTTIADLAVATDARQIKTGSLCRSDRVAKYNRLLQIEREL 411 Query: 418 GDKAVFAGRK 427 D+A +AG++ Sbjct: 412 NDQAPYAGKE 421 >6O4N-A nrPDB Length = 432 Score = 380 bits (975), Expect = e-106, Method: Compositional matrix adjust. Identities = 222/440 (50%), Positives = 286/440 (65%), Gaps = 26/440 (5%) Query: 1 MAMQKIFAREILDSRGNPTVEVDLHTAKGRF-RAAVPSGASTGIYEALELRDGDKSRYLG 59 + + I AREILDSRG PT+ V + T G F A VPSGASTGI EALELRD D RY G Sbjct: 12 VVISDIEAREILDSRGYPTLCVKVITNTGTFGEACVPSGASTGIKEALELRDKDPKRYQG 71 Query: 60 KGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVC 119 KGVL+A+ ++ K L PAL + SV DQ D MI+ DGT NK K GANAILGVSLA+ Sbjct: 72 KGVLQAISNVEKVLVPAL--QGFSVFDQITADAIMIDADGTPNKEKLGANAILGVSLALA 129 Query: 120 KAGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFK 179 KA A PLYR+ L G+ VLP P N+INGG HA N L QEFMI P+ A S K Sbjct: 130 KAAANTLQRPLYRY---LGGSFSHVLPCPMMNLINGGMHATNGLQFQEFMIRPISAPSLK 186 Query: 180 EAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDK 239 EA+R+GAEV++ LK +++ + + AT VGDEGGFAPN+ N EAL+LL TAI+ AG+ + Sbjct: 187 EAVRMGAEVFNALKKILQNR--QLATGVGDEGGFAPNLASNAEALDLLLTAIETAGFTPR 244 Query: 240 --VVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFD 297 + + +D AAS FY D KS D ++G L + ++YP+ SIED Sbjct: 245 EDISLALDCAASSFYNTQDKTYDGKSYAD--------QVGILAE-LCEHYPIDSIEDGLA 295 Query: 298 QDDWATWTSFLS---GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESI 354 ++D+ W LS G +Q+VGDDL VTN IA+ + + N +L+K NQIG++TE+ Sbjct: 296 EEDFEGW-KLLSETLGDRVQLVGDDLFVTNSALIAEGIAQGLANAVLIKPNQIGTLTETA 354 Query: 355 QACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIE 414 +A +LA G+ ++SHRSGETEDT IADL V TGQIKTG+ RSER+AKYN+LM IE Sbjct: 355 EAIRLATIQGYATILSHRSGETEDTTIADLAVAFNTGQIKTGSLSRSERIAKYNRLMAIE 414 Query: 415 EALGDKAVFAGRKFRNPKAK 434 E +G +A+F + NP +K Sbjct: 415 EEMGPEALF---QDSNPFSK 431 >6J36-A nrPDB Length = 460 Score = 362 bits (930), Expect = e-100, Method: Compositional matrix adjust. Identities = 217/455 (47%), Positives = 296/455 (65%), Gaps = 32/455 (7%) Query: 3 MQKIFAREILDSRGNPTVEVDLHTAKGRFRAA-VPSGASTGIYEALELRDGDK----SRY 57 + K+FAREILDSRGNPT++VD++T G F +A VPSGASTG EALELRD + + Y Sbjct: 4 ITKVFAREILDSRGNPTIQVDVYTLAGGFGSAIVPSGASTGSREALELRDTNTKYADNWY 63 Query: 58 LGKGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLA 117 KGV+ AV+++N + P ++ L +Q +D+ +IELDGT NK K GANAILGVSLA Sbjct: 64 GQKGVMTAVDNVNNIIAPEII--GLCCKNQRLIDQKIIELDGTPNKEKLGANAILGVSLA 121 Query: 118 VCKAGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASS 177 V KA A E +PL+R++ NP L +PVP NVINGG HA N L QEFMI+P+G + Sbjct: 122 VAKAAANELRMPLFRYLG--GTNPTL-MPVPMLNVINGGEHASNTLDFQEFMIMPLGFRT 178 Query: 178 FKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGY- 236 FKEA++ +V+H+L ++K K G + T VGDEGGFAPN + +AL+ L AI+ +G+ Sbjct: 179 FKEALQAANKVFHNLAKLLK-KSGFE-TQVGDEGGFAPNFNSHEQALDFLVDAIKESGFN 236 Query: 237 -----PDKVVIGMDVAASEFYRNGKY--------DLDFKSPD-DPARHISGEKLGELYKS 282 + V I +D AASEFY KY L D D + E+L Y Sbjct: 237 PGFKGENAVAIAIDAAASEFYNGQKYVFKKLKAASLSKNQADLDEKFEFNSEELLNYYGQ 296 Query: 283 FIKNYPVVSIEDPFDQDDWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCL 340 + YP++SIED F + DW + +F G + QIVGDDLTVTN + + +A+ KA N + Sbjct: 297 LLAKYPIISIEDGFAESDWQGFIAFNQKYGNNHQIVGDDLTVTNVEILKKAINLKAINSI 356 Query: 341 LLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCR 400 L+K+NQIG+++E++ A LAQ +G ++SHRSGE+EDT IADL V + +GQIKTG+ R Sbjct: 357 LIKLNQIGTLSETLDAIHLAQKSGMTAVISHRSGESEDTTIADLAVAVSSGQIKTGSLSR 416 Query: 401 SERLAKYNQLMRIEEALGD--KAVFAGRK-FRNPK 432 ++R+AKYN+L+ IEE L KA + GR+ F N K Sbjct: 417 TDRIAKYNRLLVIEEYLNSYAKADYIGREVFYNLK 451 >3QN3-A nrPDB Length = 417 Score = 361 bits (927), Expect = e-100, Method: Compositional matrix adjust. Identities = 206/427 (48%), Positives = 280/427 (65%), Gaps = 22/427 (5%) Query: 1 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAA-VPSGASTGIYEALELRDGDKSRYLG 59 + ++ + A E+LDSRGNPTV+ ++ + G AA VPSGASTG EALELRD D+ R+ G Sbjct: 5 LVIEDVRAYEVLDSRGNPTVKAEVTLSDGSVGAAIVPSGASTGSKEALELRDNDE-RFGG 63 Query: 60 KGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVC 119 KGVLKAV ++N+T+ +L L +Q ++D + ELDGT N S GANA LGVS+A Sbjct: 64 KGVLKAVANVNETIADEIL--GLDAFNQTQLDDTLRELDGTNNYSNLGANATLGVSMATA 121 Query: 120 KAGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFK 179 +A AA G+PLYR+ L G +LPVP N+INGG+HA N + QEFMI+P G +SFK Sbjct: 122 RAAAAALGMPLYRY---LGGANASILPVPMCNIINGGAHANNNVDFQEFMIMPFGFTSFK 178 Query: 180 EAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDK 239 EA+R E+Y LK + A G +T +GDEGGFAPN+ N E ++LL T I+ AGY ++ Sbjct: 179 EALRSVCEIYAILKKEL-ANSGH-STALGDEGGFAPNLANNTEPIDLLMTCIKKAGYENR 236 Query: 240 VVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQD 299 V I +DVA++EF+++GKY ++ K+ S E L E Y YP+ SIED ++ Sbjct: 237 VKIALDVASTEFFKDGKYHMEGKA-------FSSEALIERYVELCAKYPICSIEDGLAEN 289 Query: 300 DWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQAC 357 D+ W G IQ+VGDDL VTN + + + KK N +L+K NQIG++T++++ Sbjct: 290 DFEGWIKLTEKLGNKIQLVGDDLFVTNEDILREGIIKKMANAVLIKPNQIGTITQTMRTV 349 Query: 358 KLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIE--- 414 +LAQ N + ++SHRSGE+ED FIAD V L TGQIKTGA R ER AKYN+L+ IE Sbjct: 350 RLAQRNNYKCVMSHRSGESEDAFIADFAVALNTGQIKTGALARGERTAKYNRLLEIEFES 409 Query: 415 -EALGDK 420 E LG+K Sbjct: 410 DEYLGEK 416 >4MMW-A nrPDB Length = 405 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 19/73 (26%), Positives = 38/73 (52%) Query: 292 IEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVT 351 IE+P D+ +++ +DI +VG + A+ ++ AC+ L VN +G +T Sbjct: 254 IEEPMDEQSLSSYKWLSDNLDIPVVGPESAAGKHWHRAEWIKAGACDILRTGVNDVGGIT 313 Query: 352 ESIQACKLAQSNG 364 +++ LA++ G Sbjct: 314 PALKTMHLAEAFG 326 >3R11-A nrPDB Length = 379 Score = 35.0 bits (79), Expect = 0.065, Method: Compositional matrix adjust. Identities = 28/115 (24%), Positives = 50/115 (43%), Gaps = 29/115 (25%) Query: 255 GKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQ 314 KY L+ + + P ++ + + E+ K N PVV+ E FD D Sbjct: 210 NKYSLNVEIIEQPVKYYDIKAMAEITK--FSNIPVVADESVFDAKD-------------- 253 Query: 315 IVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMV 369 +R+ ++++ACN + +K+ + G + E+ + KLA S G MV Sbjct: 254 ----------AERV---IDEQACNMINIKLAKTGGILEAQKIKKLADSAGISCMV 295 >3IK4-A nrPDB Length = 365 Score = 33.5 bits (75), Expect = 0.17, Method: Compositional matrix adjust. Identities = 21/87 (24%), Positives = 39/87 (44%), Gaps = 6/87 (6%) Query: 285 KNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDD--LTVTNPKRIAQAVEKKACNCLLL 342 ++ P+V E P ++DWA + + D+ + + RIA+ N L+ Sbjct: 213 ESIPMVLFEQPLPREDWAGMAQVTAQSGFAVAADESARSAHDVLRIAREGTASVINIKLM 272 Query: 343 KVNQIGSVTESIQACKLAQSNGWGVMV 369 K V E ++ +AQ+ G G+M+ Sbjct: 273 KAG----VAEGLKMIAIAQAAGLGLMI 295 >3ERV-A nrPDB Length = 236 Score = 33.1 bits (74), Expect = 0.24, Method: Compositional matrix adjust. Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 8/80 (10%) Query: 235 GYPDKVVIGMDVAASE----FYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVV 290 G P++ +G SE Y + L K + A ++G+ + ELYKS PVV Sbjct: 87 GNPNEGFVGNIYTFSESGYGVYHGPLFQLAKKYLPNKAVDLTGKSIEELYKSVKAGQPVV 146 Query: 291 SIED----PFDQDDWATWTS 306 I + P D+D++ TW + Sbjct: 147 IITNATFAPLDEDEFTTWET 166 >3G68-A nrPDB Length = 352 Score = 32.0 bits (71), Expect = 0.51, Method: Compositional matrix adjust. Identities = 32/132 (24%), Positives = 62/132 (46%), Gaps = 10/132 (7%) Query: 305 TSFLSGVDIQ-----IVGDDLTVTNPKRIAQAVEK-KACNCLLLKVNQIGSVTESIQACK 358 TS+ SGV +Q ++ D+ P I + K N L++ V+Q GS + A K Sbjct: 44 TSYHSGVQVQPYLQNLLDIDVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMK 103 Query: 359 LAQSNGWGV--MVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEA 416 LA+ G + M ++ ++ I+D ++ + G+ K+GA + K N ++ + Sbjct: 104 LAEDKGCKIASMAGCKNALIDE--ISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQI 161 Query: 417 LGDKAVFAGRKF 428 +K + + K+ Sbjct: 162 AREKGIISSEKY 173 >1WUE-A nrPDB Length = 386 Score = 31.6 bits (70), Expect = 0.64, Method: Compositional matrix adjust. Identities = 18/80 (22%), Positives = 37/80 (46%), Gaps = 1/80 (1%) Query: 284 IKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLK 343 + +Y + IE PF DD+ + +I D+ + + K A+ +C + LK Sbjct: 224 LDHYQLAMIEQPFAADDFLDHAQLQRELKTRICLDE-NIRSLKDCQVALALGSCRSINLK 282 Query: 344 VNQIGSVTESIQACKLAQSN 363 + ++G + E+++ Q N Sbjct: 283 IPRVGGIHEALKIAAFCQEN 302 >4MGG-A nrPDB Length = 369 Score = 31.2 bits (69), Expect = 0.85, Method: Compositional matrix adjust. Identities = 25/97 (25%), Positives = 44/97 (45%), Gaps = 15/97 (15%) Query: 319 DLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNG--------WG---- 366 D + P + + + + A +C+ LK++++G +T++ L ++G WG Sbjct: 243 DEVIDGPNTLVRGIAEDAMDCINLKISKVGGLTKAKLMRDLCIAHGIPMTIEDTWGGDIV 302 Query: 367 -VMVSH--RSGETEDTFIADLVVGLCTGQIKTGAPCR 400 ++H RS +E TF A T I GAP R Sbjct: 303 TAAIAHLARSTPSEFTFSATDFNSYGTVDIAEGAPKR 339 >3S5S-A nrPDB Length = 389 Score = 30.0 bits (66), Expect = 1.8, Method: Compositional matrix adjust. Identities = 23/100 (23%), Positives = 42/100 (42%), Gaps = 6/100 (6%) Query: 272 SGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFL--SGVDIQIVGDDLTVTNPKRIA 329 +GE L + + V +E P +DDW +GVD+ + + R+A Sbjct: 201 AGEALALVAHARRLGADVALLEQPVPRDDWDGMKEVTRRAGVDVAADESAASAEDVLRVA 260 Query: 330 QAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMV 369 N L+K G + E++ +A++ G G+M+ Sbjct: 261 AERAATVVNIKLMK----GGIAEALDIAAVARAAGLGLMI 296 >1VE5-A nrPDB Length = 311 Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust. Identities = 31/113 (27%), Positives = 53/113 (46%), Gaps = 13/113 (11%) Query: 140 NPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE--AMRIGAEVYHHLKGVIK 197 NP +L V + N G ++A L ++ +++P AS +K+ A GAEV +GV Sbjct: 64 NPKGLLAVSSGNHAQGVAYAAQVLGVKALVVMPEDASPYKKACARAYGAEVVD--RGVTA 121 Query: 198 AKYGKDATNVGDEGGFA-------PNIL--ENNEALELLKTAIQAAGYPDKVV 241 + A + +E G+A P ++ + LELL A + +P V+ Sbjct: 122 KNREEVARALQEETGYALIHPFDDPLVIAGQGTAGLELLAQAGRMGVFPGAVL 174 >5X3E-A nrPDB Length = 449 Score = 30.0 bits (66), Expect = 2.2, Method: Compositional matrix adjust. Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 2/70 (2%) Query: 230 AIQAAGYPDKVVIGMDVAASEFYRNGKYDL--DFKSPDDPARHISGEKLGELYKSFIKNY 287 AI+ +GY D +V + V E Y N YDL D ++ R I ++ ++Y K+ Sbjct: 203 AIKLSGYNDDMVCSVFVTYVEIYNNYCYDLLEDARNGVLTKREIRHDRQQQMYVDGAKDV 262 Query: 288 PVVSIEDPFD 297 V S E+ + Sbjct: 263 EVSSSEEALE 272 >5A9Z-CA nrPDB Length = 593 Score = 28.9 bits (63), Expect = 4.7, Method: Compositional matrix adjust. Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 8/89 (8%) Query: 63 LKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFG---ANAILGVSLAVC 119 LK + INK P + VVDQ V + LD T+ + F A+A+ G++ + Sbjct: 121 LKPIVVINKVDRPG--ARPDWVVDQ--VFDLFVNLDATDEQLDFAIVYASALNGIA-GLD 175 Query: 120 KAGAAEKGVPLYRHIADLAGNPDLVLPVP 148 AE PLY+ I D PD+ L P Sbjct: 176 HEDMAEDMTPLYQAIVDHVPAPDVDLDGP 204 >3GG2-A nrPDB Length = 450 Score = 28.9 bits (63), Expect = 5.1, Method: Compositional matrix adjust. Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 1/64 (1%) Query: 223 ALELLKTAIQAAGYPDKVVIGMDVAAS-EFYRNGKYDLDFKSPDDPARHISGEKLGELYK 281 + L++ AIQ +V+I D+A++ EF + G DF PD + ++ EL Sbjct: 128 SYRLIRKAIQEELDKREVLIDFDIASNPEFLKEGNAIDDFMKPDRVVVGVDSDRARELIT 187 Query: 282 SFIK 285 S K Sbjct: 188 SLYK 191 >4HNL-A nrPDB Length = 421 Score = 28.5 bits (62), Expect = 6.1, Method: Compositional matrix adjust. Identities = 42/185 (22%), Positives = 68/185 (36%), Gaps = 24/185 (12%) Query: 187 EVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPD----KVVI 242 ++YH + + A Y +G GG N L+ + I + + + + Sbjct: 156 DLYHEIDRFLAAGYRYIRCQLGFYGG-------NPSQLQTPEEPISGSYFDQTDYMETTL 208 Query: 243 GMDVAASEFYRNGKYDL-DFKSPDDPARHISGEKLGELYKSFIKNYPVVSIED--PFDQD 299 M A E Y N L D P + I K E Y+ F +ED P DQ Sbjct: 209 KMFAAIKEKYGNQFQMLHDVHERLHPNQAIQFAKAAEPYQLFF-------LEDILPPDQS 261 Query: 300 DWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKL 359 W T S I G+ NP + V+ + + + V+QIG +T +++ Sbjct: 262 HWLTQLRSQSATPIA-TGE--LFNNPMEWQELVKNRQIDFMRAHVSQIGGITPALKLAHF 318 Query: 360 AQSNG 364 + G Sbjct: 319 CDAMG 323 >6ARG-A nrPDB Length = 399 Score = 28.1 bits (61), Expect = 7.2, Method: Compositional matrix adjust. Identities = 34/129 (26%), Positives = 51/129 (39%), Gaps = 23/129 (17%) Query: 79 EKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYR-----H 133 E KL ++ + V K + D + SKF L + A+ AG + + + Sbjct: 268 EAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKALKHAGVGQDAIDAFEINEAFS 327 Query: 134 IADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLK 193 + LA L +P N+ G G+ P+GAS GA + L Sbjct: 328 VVALANMKLLGIPEEKVNLHGGAVAIGH----------PIGAS--------GARILTTLL 369 Query: 194 GVIKAKYGK 202 GV+KAK GK Sbjct: 370 GVLKAKKGK 378 >1TP9-A nrPDB Length = 162 Score = 28.1 bits (61), Expect = 8.0, Method: Compositional matrix adjust. Identities = 14/42 (33%), Positives = 20/42 (47%), Gaps = 2/42 (4%) Query: 263 SPDDPARHISG--EKLGELYKSFIKNYPVVSIEDPFDQDDWA 302 +P +H+ G EK GEL + +S+ DPF WA Sbjct: 48 TPTCSLKHVPGFIEKAGELKSKGVTEILCISVNDPFVMKAWA 89 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2XSX-A nrPDB 753 0.0 3UJR-A nrPDB 740 0.0 3B97-A nrPDB 736 0.0 1PDZ-A nrPDB 711 0.0 5WRO-A nrPDB 685 0.0 3QTP-A nrPDB 681 0.0 4G7F-A nrPDB 665 0.0 3OTR-A nrPDB 665 0.0 2PU1-A nrPDB 664 0.0 2XH7-A nrPDB 651 0.0 5BOE-A nrPDB 648 0.0 1IYX-A nrPDB 645 0.0 4A3R-A nrPDB 640 0.0 4MKS-A nrPDB 639 0.0 3ZLH-A nrPDB 639 0.0 1W6T-A nrPDB 636 0.0 2PA6-A nrPDB 615 e-176 4Z1Y-A nrPDB 613 e-176 5J04-A nrPDB 610 e-175 6NB2-A nrPDB 604 e-173 6BFZ-A nrPDB 594 e-170 3TQP-A nrPDB 593 e-170 3UJ2-A nrPDB 591 e-169 6O4N-A nrPDB 586 e-168 6J36-A nrPDB 569 e-163 3QN3-A nrPDB 566 e-162 4MMW-A nrPDB 102 3e-22 Sequences not found previously or not previously below threshold: 3R11-A nrPDB 58 1e-08 4HNL-A nrPDB 51 1e-06 3R25-A nrPDB 48 7e-06 3QLD-A nrPDB 47 1e-05 3S47-A nrPDB 47 2e-05 4GIR-A nrPDB 45 7e-05 2GGG-A nrPDB 44 2e-04 1WUE-A nrPDB 44 2e-04 3JW7-A nrPDB 43 2e-04 1TKK-A nrPDB 43 2e-04 3IK4-A nrPDB 43 3e-04 2ZC8-A nrPDB 42 5e-04 2QDE-A nrPDB 41 0.001 3TJI-A nrPDB 39 0.003 3Q4D-A nrPDB 39 0.003 3UGV-A nrPDB 39 0.004 5FJT-A nrPDB 38 0.006 3IJQ-A nrPDB 38 0.006 1WUF-A nrPDB 38 0.012 3UXL-A nrPDB 37 0.013 5X3E-A nrPDB 37 0.019 3I4K-A nrPDB 36 0.030 2OG9-A nrPDB 36 0.030 2PP0-A nrPDB 36 0.031 3I6E-A nrPDB 36 0.041 3TW9-A nrPDB 36 0.042 2PGW-A nrPDB 35 0.050 3T6C-A nrPDB 35 0.052 2P8B-A nrPDB 35 0.060 3MWC-A nrPDB 35 0.073 3SJN-A nrPDB 35 0.080 3U9I-A nrPDB 34 0.10 4MGG-A nrPDB 34 0.12 4IHC-A nrPDB 34 0.18 3K4W-A nrPDB 33 0.20 3S5S-A nrPDB 33 0.20 1NU5-A nrPDB 33 0.20 4PG8-A nrPDB 33 0.21 3G68-A nrPDB 33 0.23 3EKG-A nrPDB 32 0.42 2CHR-A nrPDB 32 0.42 3TTE-A nrPDB 32 0.43 2Z8X-A nrPDB 32 0.52 3RO6-B nrPDB 32 0.57 3ERV-A nrPDB 32 0.67 3ZVH-B nrPDB 31 1.2 5OLC-A nrPDB 31 1.2 3T8Q-A nrPDB 31 1.3 3ES8-A nrPDB 30 1.7 4GFI-A nrPDB 30 2.2 6ILH-A nrPDB 30 2.2 1JPD-X nrPDB 30 2.3 6CHD-A nrPDB 29 2.8 5HQA-A nrPDB 29 2.8 4WMZ-A nrPDB 29 2.8 6MRP-B nrPDB 29 3.5 5KR3-A nrPDB 29 3.6 4A35-A nrPDB 29 4.2 5XD7-A nrPDB 29 4.4 3DDM-A nrPDB 29 4.6 1KKR-A nrPDB 29 5.5 2JI6-A nrPDB 29 5.8 5XY3-B nrPDB 28 7.4 4GLW-A nrPDB 28 7.8 4M0X-A nrPDB 28 8.0 6D81-A nrPDB 28 9.2 5KR5-A nrPDB 28 9.9 >2XSX-A nrPDB Length = 435 Score = 753 bits (1945), Expect = 0.0, Method: Composition-based stats. Identities = 425/434 (97%), Positives = 431/434 (99%) Query: 1 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGK 60 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDK RYLGK Sbjct: 2 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGK 61 Query: 61 GVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 120 GVLKAVE+IN TLGPALL+KKLSV DQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK Sbjct: 62 GVLKAVENINSTLGPALLQKKLSVADQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 121 Query: 121 AGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 180 AGAAEKGVPLYRHIADLAGNPDL+LPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE Sbjct: 122 AGAAEKGVPLYRHIADLAGNPDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 181 Query: 181 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV 240 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV Sbjct: 182 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV 241 Query: 241 VIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDD 300 VIGMDVAASEFYRNGKYDLDFKSPDDPARHI+GEKLGELYKSFIKNYPVVSIEDPFDQDD Sbjct: 242 VIGMDVAASEFYRNGKYDLDFKSPDDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDD 301 Query: 301 WATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLA 360 WATWTSFLSGV+IQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLA Sbjct: 302 WATWTSFLSGVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLA 361 Query: 361 QSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDK 420 QSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDK Sbjct: 362 QSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDK 421 Query: 421 AVFAGRKFRNPKAK 434 A+FAGRKFRNPKAK Sbjct: 422 AIFAGRKFRNPKAK 435 >3UJR-A nrPDB Length = 443 Score = 740 bits (1912), Expect = 0.0, Method: Composition-based stats. Identities = 360/430 (83%), Positives = 397/430 (92%) Query: 2 AMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKG 61 +++KI+AREILDSRGNPTVEVDL+TAKG FRAAVPSGASTGIYEALELRDGDK RYLGKG Sbjct: 1 SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKG 60 Query: 62 VLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKA 121 VLKAV+HIN T+ PAL+ LSVV+QEK+D M+ELDGTENKSKFGANAILGVSLAVCKA Sbjct: 61 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 120 Query: 122 GAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEA 181 GAAE+ +PLYRHIA LAGN DL+LPVPAFNVINGGSHAGNKLAMQEFMILPVGA SF++A Sbjct: 121 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 180 Query: 182 MRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVV 241 MR+GAEVYH LKGVIK KYGKDATNVGDEGGFAPNILEN+EALEL+K AI AGY +K+V Sbjct: 181 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIV 240 Query: 242 IGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDW 301 IGMDVAASEFYR+GKYDLDFKSP DP+R+I+G++LG LY+ F+++YPVVSIEDPFDQDDW Sbjct: 241 IGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDW 300 Query: 302 ATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQ 361 A W+ F + V IQIVGDDLTVTNPKRI +AVE+KACNCLLLKVNQIGSVTE+IQACKLAQ Sbjct: 301 AAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQ 360 Query: 362 SNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKA 421 NGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEE LGD+A Sbjct: 361 ENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEA 420 Query: 422 VFAGRKFRNP 431 FAG FRNP Sbjct: 421 RFAGHNFRNP 430 >3B97-A nrPDB Length = 433 Score = 736 bits (1900), Expect = 0.0, Method: Composition-based stats. Identities = 363/433 (83%), Positives = 397/433 (91%) Query: 2 AMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKG 61 ++ KI AREI DSRGNPTVEVDL T+KG FRAAVPSGASTGIYEALELRD DK+RY+GKG Sbjct: 1 SILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKG 60 Query: 62 VLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKA 121 V KAVEHINKT+ PAL+ KKL+V +QEK+DK MIE+DGTENKSKFGANAILGVSLAVCKA Sbjct: 61 VSKAVEHINKTIAPALVSKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKA 120 Query: 122 GAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEA 181 GA EKGVPLYRHIADLAGN +++LPVPAFNVINGGSHAGNKLAMQEFMILPVGA++F+EA Sbjct: 121 GAVEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFREA 180 Query: 182 MRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVV 241 MRIGAEVYH+LK VIK KYGKDATNVGDEGGFAPNILEN E LELLKTAI AGY DKVV Sbjct: 181 MRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYTDKVV 240 Query: 242 IGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDW 301 IGMDVAASEF+R+GKYDLDFKSPDDP+R+IS ++L +LYKSFIK+YPVVSIEDPFDQDDW Sbjct: 241 IGMDVAASEFFRSGKYDLDFKSPDDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDDW 300 Query: 302 ATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQ 361 W F + IQ+VGDDLTVTNPKRIA+AV +K+CNCLLLKVNQIGSVTES+QACKLAQ Sbjct: 301 GAWQKFTASAGIQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACKLAQ 360 Query: 362 SNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKA 421 +NGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQL+RIEE LG KA Sbjct: 361 ANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSKA 420 Query: 422 VFAGRKFRNPKAK 434 FAGR FRNP AK Sbjct: 421 KFAGRNFRNPLAK 433 >1PDZ-A nrPDB Length = 434 Score = 711 bits (1836), Expect = 0.0, Method: Composition-based stats. Identities = 309/432 (71%), Positives = 362/432 (83%), Gaps = 2/432 (0%) Query: 2 AMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKG 61 ++ K+FAR I DSRGNPTVEVDL+T+KG FRAAVPSGASTG++EALE+RDGDKS+Y GK Sbjct: 2 SITKVFARTIFDSRGNPTVEVDLYTSKGLFRAAVPSGASTGVHEALEMRDGDKSKYHGKS 61 Query: 62 VLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKA 121 V AV+++N + P +++ L V Q++ D+FM +LDGTENKS GANAILGVSLA+CKA Sbjct: 62 VFNAVKNVNDVIVPEIIKSGLKVTQQKECDEFMCKLDGTENKSSLGANAILGVSLAICKA 121 Query: 122 GAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEA 181 GAAE G+PLYRHIA+LA +++LPVPAFNVINGGSHAGNKLAMQEFMILP GA+SF EA Sbjct: 122 GAAELGIPLYRHIANLANYDEVILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEA 181 Query: 182 MRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVV 241 MR+G EVYHHLK VIKA++G DAT VGDEGGFAPNIL N +AL+L++ AI+ AGY K+ Sbjct: 182 MRMGTEVYHHLKAVIKARFGLDATAVGDEGGFAPNILNNKDALDLIQEAIKKAGYTGKIE 241 Query: 242 IGMDVAASEFYR-NGKYDLDFKSP-DDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQD 299 IGMDVAASEFY+ N YDLDFK+ +D ++ ISG++L ++Y F K++P+VSIEDPFDQD Sbjct: 242 IGMDVAASEFYKQNNIYDLDFKTANNDGSQKISGDQLRDMYMEFCKDFPIVSIEDPFDQD 301 Query: 300 DWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKL 359 DW TW+ SG IQIVGDDLTVTNPKRI AVEKKAC CLLLKVNQIGSVTESI A L Sbjct: 302 DWETWSKMTSGTTIQIVGDDLTVTNPKRITTAVEKKACKCLLLKVNQIGSVTESIDAHLL 361 Query: 360 AQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGD 419 A+ NGWG MVSHRSGETED FIADLVVGLCTGQIKTGAPCRSERLAKYNQ++RIEE LG Sbjct: 362 AKKNGWGTMVSHRSGETEDCFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGS 421 Query: 420 KAVFAGRKFRNP 431 A FAG+ FR P Sbjct: 422 GAKFAGKNFRAP 433 >5WRO-A nrPDB Length = 439 Score = 685 bits (1768), Expect = 0.0, Method: Composition-based stats. Identities = 315/433 (72%), Positives = 360/433 (83%), Gaps = 1/433 (0%) Query: 1 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGK 60 ++ I AR+I DSRGNPTVEVDL T G FRAAVPSGASTG++EALELRD DK+ Y GK Sbjct: 7 FTIKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDNDKANYHGK 66 Query: 61 GVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 120 VLKAV H+N TLGP L++ L VVDQ +D FMI+LDGTENKSKFGANAILGVSLAV K Sbjct: 67 SVLKAVGHVNDTLGPELIKANLDVVDQASIDNFMIKLDGTENKSKFGANAILGVSLAVAK 126 Query: 121 AGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 180 AGAA+KGVPLY+HIADLAGN +++LPVPAFNVINGGSHAGNKLAMQEFMILP GA+SF E Sbjct: 127 AGAAKKGVPLYKHIADLAGNKEIILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTE 186 Query: 181 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV 240 AM++G+EVYHHLK VIKAK+G DAT VGDEGGFAPNI N EAL L+ AI AGY K+ Sbjct: 187 AMKMGSEVYHHLKNVIKAKFGLDATAVGDEGGFAPNIQSNKEALNLISDAIAKAGYTGKI 246 Query: 241 VIGMDVAASEFYRNGKYDLDFKSPD-DPARHISGEKLGELYKSFIKNYPVVSIEDPFDQD 299 IGMDVAASEFY++G+YDLDFK+ D ++ + +KL LY+ FIK++P+VSIEDPFDQD Sbjct: 247 EIGMDVAASEFYKDGQYDLDFKNEKSDKSQWLPADKLANLYQEFIKDFPIVSIEDPFDQD 306 Query: 300 DWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKL 359 W W++ DIQIVGDDLTVTNPKRIA AVEKKACNCLLLKVNQIG+VTESI A L Sbjct: 307 HWEAWSNLTGCTDIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGTVTESIAAHLL 366 Query: 360 AQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGD 419 A+ NGWG MVSHRSGETED+FI DLVVGL TGQIKTGAPCRSERLAKYNQ++RIEE +G Sbjct: 367 AKKNGWGTMVSHRSGETEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEIGA 426 Query: 420 KAVFAGRKFRNPK 432 FAG+ FR P+ Sbjct: 427 GVKFAGKSFRKPQ 439 >3QTP-A nrPDB Length = 441 Score = 681 bits (1758), Expect = 0.0, Method: Composition-based stats. Identities = 273/439 (62%), Positives = 335/439 (76%), Gaps = 9/439 (2%) Query: 1 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGK 60 M++QK+ AREILDSRGNPT+EV++ T KG FR+ VPSGASTG++EA+ELRDGDK RY GK Sbjct: 6 MSIQKVHAREILDSRGNPTIEVEITTGKGMFRSCVPSGASTGVHEAVELRDGDKKRYGGK 65 Query: 61 GVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 120 GVLKAVE++N +GPALL K +V++Q ++D+ MI+LDGT NK K GANAILG S+++C+ Sbjct: 66 GVLKAVENVNTIIGPALLGK--NVLNQAELDEMMIKLDGTNNKGKLGANAILGCSMSICR 123 Query: 121 AGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 180 A AAEKG+PLY+++A+L G+ ++ +PVP FNVINGG+HAGN LAMQEFMI P GA++F E Sbjct: 124 AAAAEKGLPLYKYLAELTGHKEMTMPVPCFNVINGGAHAGNALAMQEFMICPTGATNFHE 183 Query: 181 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV 240 A+R+ AE Y LK VIKAKYG+DATNVGDEGGFAPN+ EAL+LL AI AGY K+ Sbjct: 184 ALRMAAETYQCLKVVIKAKYGQDATNVGDEGGFAPNVSGAREALDLLVEAIAKAGYTGKI 243 Query: 241 VIGMDVAASEFYRNG--KYDLDFKSP---DDPARHISGEKLGELYKSFIKNYPVVSIEDP 295 I MD AASEFY KYDL K P DP+ + L Y + K+YP+ SIEDP Sbjct: 244 EIAMDCAASEFYNEETKKYDLGKKIPADKKDPSLVKDVDGLIAEYVDYGKHYPIASIEDP 303 Query: 296 FDQDDWATWTSFL-SGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESI 354 F +DDWA W F + QIVGDDL VTNP R+ A++K ACN +L+KVNQIG++TE+ Sbjct: 304 FAEDDWAAWNKFTVEHGNFQIVGDDLLVTNPARVQMAMDKNACNSVLIKVNQIGTLTETF 363 Query: 355 QACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIE 414 + K+AQ GWGVM SHRSGETEDTFIADLVVGL QIKTGAPCRSERL KYNQLMRIE Sbjct: 364 KTIKMAQEKGWGVMASHRSGETEDTFIADLVVGLNCKQIKTGAPCRSERLCKYNQLMRIE 423 Query: 415 EALGDKAVFAGRKFRNPKA 433 E LG +AG+ +RN A Sbjct: 424 EELG-NIPYAGKNWRNSTA 441 >4G7F-A nrPDB Length = 429 Score = 665 bits (1717), Expect = 0.0, Method: Composition-based stats. Identities = 266/427 (62%), Positives = 318/427 (74%), Gaps = 8/427 (1%) Query: 1 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGK 60 M +QK+ REILDSRGNPTVEV++ T G FR+AVPSGASTGI+EA ELRD DK RYLGK Sbjct: 1 MTIQKVHGREILDSRGNPTVEVEVTTELGVFRSAVPSGASTGIHEACELRDDDKRRYLGK 60 Query: 61 GVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 120 G L AV+++N L PAL+ K + Q +DK M +LDGT NKSK GANAILG S+A+ K Sbjct: 61 GCLNAVKNVNDVLAPALVGK--DELQQSTLDKLMRDLDGTPNKSKLGANAILGCSMAISK 118 Query: 121 AGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 180 A AA KGVPLYR++A+LAG ++ LPVP FNVINGG HAGN L QEFMI PV A SF E Sbjct: 119 AAAARKGVPLYRYLAELAGTKEVRLPVPCFNVINGGKHAGNALPFQEFMIAPVKAGSFNE 178 Query: 181 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV 240 A+R+GAEVYH LK +IK KYG+DA NVGDEGGFAP I + NE L +L AI+ AG+ + Sbjct: 179 ALRMGAEVYHSLKSIIKKKYGQDAVNVGDEGGFAPPITDINEPLPILMEAIEQAGHKGRF 238 Query: 241 VIGMDVAASEFYRNGK--YDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQ 298 I MD AASE Y K Y+L FKSP+ A ++ ++L E Y ++ YP+VS+EDP+DQ Sbjct: 239 AICMDSAASETYDENKKQYNLTFKSPE--ATWVTAKQLAETYAKWVSEYPIVSLEDPYDQ 296 Query: 299 DDWATWTSFLSGV--DIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQA 356 DD+ + + Q+VGDDLTVTN RI A+EKKACN LLLK+NQIG++TE+I+A Sbjct: 297 DDFDGFAGITEALKGKAQVVGDDLTVTNVSRIKTAIEKKACNSLLLKINQIGTITEAIEA 356 Query: 357 CKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEA 416 K SNGW VMVSHRSGETEDT+IADLVVGL TGQIKTGAPCR ER AK NQL+RIEE Sbjct: 357 SKFCMSNGWSVMVSHRSGETEDTYIADLVVGLGTGQIKTGAPCRGERTAKLNQLLRIEEE 416 Query: 417 LGDKAVF 423 LG A F Sbjct: 417 LGAHAKF 423 >3OTR-A nrPDB Length = 452 Score = 665 bits (1716), Expect = 0.0, Method: Composition-based stats. Identities = 285/445 (64%), Positives = 347/445 (77%), Gaps = 15/445 (3%) Query: 1 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGK 60 + ++ I AREILDSRGNPT+EVD+ T G FRAAVPSGASTGIYEALELRD D RYLGK Sbjct: 2 VVIKDIVAREILDSRGNPTIEVDVSTEGGVFRAAVPSGASTGIYEALELRDKDPKRYLGK 61 Query: 61 GVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIE-LDGTEN-----KSKFGANAILGV 114 GVL AVE + + + PALL K DQ+ +D M+E LDGT+N KSK GANAILGV Sbjct: 62 GVLNAVEIVRQEIKPALLGK--DPCDQKGIDMLMVEQLDGTKNEWGYSKSKLGANAILGV 119 Query: 115 SLAVCKAGAAEKGVPLYRHIADLAGN--PDLVLPVPAFNVINGGSHAGNKLAMQEFMILP 172 S+A C+AGAA KG+PLY++IA LAG +V+PVP FNVINGG HAGN LA+QEF+I P Sbjct: 120 SIACCRAGAASKGLPLYKYIATLAGKTIDKMVMPVPFFNVINGGEHAGNGLALQEFLIAP 179 Query: 173 VGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQ 232 VGA + +EA+R G+E YHHLK VIK KYG DATNVGDEGGFAPN+ EAL LL AI+ Sbjct: 180 VGAPNIREAIRYGSETYHHLKNVIKNKYGLDATNVGDEGGFAPNVATAEEALNLLVEAIK 239 Query: 233 AAGYPDKVVIGMDVAASEFYR--NGKYDLDFKS-PDDPARHISGEKLGELYKSFIKNYPV 289 AAGY K+ I D AASEFY+ KYDLD+K + ++H++GEKL E+Y+ ++K YP+ Sbjct: 240 AAGYEGKIKIAFDAAASEFYKQDEKKYDLDYKCKTKNASKHLTGEKLKEVYEGWLKKYPI 299 Query: 290 VSIEDPFDQDDWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQI 347 +S+EDPFDQDD+A++++F G Q++GDD+ VTN RI +A++ KACNCLLLKVNQI Sbjct: 300 ISVEDPFDQDDFASFSAFTKDVGEKTQVIGDDILVTNILRIEKALKDKACNCLLLKVNQI 359 Query: 348 GSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKY 407 GSVTE+I+AC LAQ +GWGV VSHRSGETED+FIADLVVGL GQIK+G+PCRSERL KY Sbjct: 360 GSVTEAIEACLLAQKSGWGVQVSHRSGETEDSFIADLVVGLRCGQIKSGSPCRSERLCKY 419 Query: 408 NQLMRIEEALGDKAVFAGRKFRNPK 432 NQLMRIEE+LG V+AG FR+PK Sbjct: 420 NQLMRIEESLGADCVYAGESFRHPK 444 >2PU1-A nrPDB Length = 432 Score = 664 bits (1713), Expect = 0.0, Method: Composition-based stats. Identities = 263/427 (61%), Positives = 324/427 (75%), Gaps = 8/427 (1%) Query: 1 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGK 60 M +QK+ RE+LDSRGNPTVEV++ T KG FR+AVPSGASTG+YEA ELRDGDK RY+GK Sbjct: 4 MTIQKVHGREVLDSRGNPTVEVEVTTEKGVFRSAVPSGASTGVYEACELRDGDKKRYVGK 63 Query: 61 GVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 120 G L+AV+++N+ +GPAL+ + + QE++D M+ LDGT NK K GANAILG S+A+ K Sbjct: 64 GCLQAVKNVNEVIGPALIGR--DELKQEELDTLMLRLDGTPNKGKLGANAILGCSMAISK 121 Query: 121 AGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 180 A AA KGVPLYR++A LAG +L LPVP FNVINGG HAGN L QEFMI PV A+SF E Sbjct: 122 AAAAAKGVPLYRYLASLAGTKELRLPVPCFNVINGGKHAGNALPFQEFMIAPVKATSFSE 181 Query: 181 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV 240 A+R+G+EVYH L+G+IK KYG+DA NVGDEGGFAP I + NE L +L AI+ AG+ K Sbjct: 182 ALRMGSEVYHSLRGIIKKKYGQDAVNVGDEGGFAPPIKDINEPLPILMEAIEEAGHRGKF 241 Query: 241 VIGMDVAASEFY--RNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQ 298 I MD AASE Y + +Y+L FKSP+ ++ E+L E Y + +YP+VSIEDP+DQ Sbjct: 242 AICMDCAASETYDEKKQQYNLTFKSPE--PTWVTAEQLRETYCKWAHDYPIVSIEDPYDQ 299 Query: 299 DDWATWTSFLSGV--DIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQA 356 DD+A + + QIVGDDLTVTN +RI A+EKKACN LLLK+NQIG+++E+I + Sbjct: 300 DDFAGFAGITEALKGKTQIVGDDLTVTNTERIKMAIEKKACNSLLLKINQIGTISEAIAS 359 Query: 357 CKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEA 416 KL NGW VMVSHRSGETEDT+IADLVV L +GQIKTGAPCR ER AK NQL+RIEE Sbjct: 360 SKLCMENGWSVMVSHRSGETEDTYIADLVVALGSGQIKTGAPCRGERTAKLNQLLRIEEE 419 Query: 417 LGDKAVF 423 LG A F Sbjct: 420 LGAHAKF 426 >2XH7-A nrPDB Length = 443 Score = 651 bits (1681), Expect = 0.0, Method: Composition-based stats. Identities = 275/430 (63%), Positives = 341/430 (79%), Gaps = 3/430 (0%) Query: 2 AMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKG 61 A+ K++AR + DSRGNPTVEV+L T KG FR+ VPSGASTG++EALE+RDGDKS+++GKG Sbjct: 1 AVSKVYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVHEALEMRDGDKSKWMGKG 60 Query: 62 VLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKA 121 VL AV+++N + PA ++ + V DQ+ VD F+I LDGT NKSK GANAILGVSLA +A Sbjct: 61 VLHAVKNVNDVIAPAFVKANIDVKDQKAVDDFLISLDGTANKSKLGANAILGVSLAASRA 120 Query: 122 GAAEKGVPLYRHIADLAGNPD--LVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFK 179 AAEK VPLY+H+ADL+ + VLPVP NV+NGGSHAG LA+QEFMI P GA +F Sbjct: 121 AAAEKNVPLYKHLADLSKSKTSPYVLPVPFLNVLNGGSHAGGALALQEFMIAPTGAKTFA 180 Query: 180 EAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDK 239 EA+RIG+EVYH+LK + K +YG A NVGDEGG APNI EAL+L+ AI+AAG+ K Sbjct: 181 EALRIGSEVYHNLKSLTKKRYGASAGNVGDEGGVAPNIQTAEEALDLIVDAIKAAGHDGK 240 Query: 240 VVIGMDVAASEFYRNGKYDLDFKSPD-DPARHISGEKLGELYKSFIKNYPVVSIEDPFDQ 298 + IG+D A+SEF+++GKYDLDFK+P+ D ++ ++G +L +LY S +K YP+VSIEDPF + Sbjct: 241 IKIGLDCASSEFFKDGKYDLDFKNPNSDKSKWLTGPQLADLYHSLMKRYPIVSIEDPFAE 300 Query: 299 DDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACK 358 DDW W+ F IQIV D LTVTNPKRIA A+EKKA + LLLKVNQIG+++ESI+A + Sbjct: 301 DDWEAWSHFFKTAGIQIVADALTVTNPKRIATAIEKKAADALLLKVNQIGTLSESIKAAQ 360 Query: 359 LAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALG 418 + + GWGVMVSHRSGETEDTFIADLVVGL TGQIKTGAP RSERLAK NQL+RIEE LG Sbjct: 361 DSFAAGWGVMVSHRSGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEELG 420 Query: 419 DKAVFAGRKF 428 D AVFAG F Sbjct: 421 DNAVFAGENF 430 >5BOE-A nrPDB Length = 442 Score = 648 bits (1673), Expect = 0.0, Method: Composition-based stats. Identities = 218/436 (50%), Positives = 300/436 (68%), Gaps = 12/436 (2%) Query: 2 AMQKIFAREILDSRGNPTVEVDLHTAKGRF-RAAVPSGASTGIYEALELRDGDKSRYLGK 60 + ++ARE+LDSRGNPTVEV++ T G F RA VPSGASTG +EA+ELRDGDKSRYLGK Sbjct: 3 IITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASTGEHEAVELRDGDKSRYLGK 62 Query: 61 GVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 120 GV KAVE++N+ + P ++E + SV+DQ +DK MI LDGT NK K GANAILGVS+AV + Sbjct: 63 GVTKAVENVNEIIAPEIIEGEFSVLDQVSIDKMMIALDGTPNKGKLGANAILGVSIAVAR 122 Query: 121 AGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 180 A A G PLY+++ G LPVP N++NGGSH+ +A QEFMILPVGA++FKE Sbjct: 123 AAADLLGQPLYKYLGGFNGKQ---LPVPMMNIVNGGSHSDAPIAFQEFMILPVGATTFKE 179 Query: 181 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--D 238 ++R G E++H+LK ++ + T VGDEGGFAP +A+E + AI+AAGY + Sbjct: 180 SLRWGTEIFHNLKSILSKR--GLETAVGDEGGFAPKFEGTEDAVETIIQAIEAAGYKPGE 237 Query: 239 KVVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQ 298 +V +G D A+SEFY NG YD + A+ + E++ + + + YP+++IED D+ Sbjct: 238 EVFLGFDCASSEFYENGVYDYSKFEGEHGAKRTAAEQV-DYLEQLVDKYPIITIEDGMDE 296 Query: 299 DDWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQA 356 +DW W G +Q+VGDDL VTN + +A+ +E N +L+KVNQIG++TE+ A Sbjct: 297 NDWDGWKQLTERIGDRVQLVGDDLFVTNTEILAKGIENGIGNSILIKVNQIGTLTETFDA 356 Query: 357 CKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEA 416 ++AQ G+ +VSHRSGETEDT IAD+ V GQIKTG+ R++R+AKYNQL+RIE+ Sbjct: 357 IEMAQKAGYTAVVSHRSGETEDTTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDE 416 Query: 417 LGDKAVFAG-RKFRNP 431 L + A + G + F N Sbjct: 417 LFETAKYDGIKSFYNL 432 >1IYX-A nrPDB Length = 432 Score = 645 bits (1664), Expect = 0.0, Method: Composition-based stats. Identities = 218/438 (49%), Positives = 298/438 (68%), Gaps = 15/438 (3%) Query: 2 AMQKIFAREILDSRGNPTVEVDLHTAKGRF-RAAVPSGASTGIYEALELRDGDKSRYLGK 60 + ++AREILDSRGNPT+EV+++T G F R VPSGASTG YEA+ELRDGDK+RY GK Sbjct: 3 IITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTGEYEAVELRDGDKARYGGK 62 Query: 61 GVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 120 GV KAV+++N + A++ V DQ +DK MI LDGT NK K GANAILGVS+AV + Sbjct: 63 GVTKAVDNVNNIIAEAII--GYDVRDQMAIDKAMIALDGTPNKGKLGANAILGVSIAVAR 120 Query: 121 AGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 180 A A VPLY + L G VLP P N+INGGSHA N + QEFMI+PVGA +FKE Sbjct: 121 AAADYLEVPLYHY---LGGFNTKVLPTPMMNIINGGSHADNSIDFQEFMIMPVGAPTFKE 177 Query: 181 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPD-- 238 A+R+GAEV+H L ++K++ AT+VGDEGGFAPN+ N E E++ AI+ AGY Sbjct: 178 ALRMGAEVFHALAAILKSR--GLATSVGDEGGFAPNLGSNEEGFEVIIEAIEKAGYVPGK 235 Query: 239 KVVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQ 298 VV+ MD A+SEFY K D + +++ + Y+ + YP++SIED D+ Sbjct: 236 DVVLAMDAASSEFYDKEKGVY--VLADSGEGEKTTDEMIKFYEELVSKYPIISIEDGLDE 293 Query: 299 DDWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQA 356 +DW + G +Q+VGDDL VTN +++++ +EK N +L+KVNQIG++TE+ +A Sbjct: 294 NDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIANSILIKVNQIGTLTETFEA 353 Query: 357 CKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEA 416 ++A+ G+ +VSHRSGETED+ I+D+ V GQIKTG+ R++R+AKYNQL+RIE+ Sbjct: 354 IEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQ 413 Query: 417 LGDKAVFAG-RKFRNPKA 433 LG+ A + G + F N KA Sbjct: 414 LGEVAEYKGLKSFYNLKA 431 >4A3R-A nrPDB Length = 430 Score = 640 bits (1651), Expect = 0.0, Method: Composition-based stats. Identities = 215/437 (49%), Positives = 298/437 (68%), Gaps = 20/437 (4%) Query: 3 MQKIFAREILDSRGNPTVEVDLHTAKGRF-RAAVPSGASTGIYEALELRDGDKSRYLGKG 61 + ++ARE+LDSRGNPTVEV+++T G F RA VPSGASTG YEA+ELRDGDK RYLGKG Sbjct: 4 IVDVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGEYEAVELRDGDKDRYLGKG 63 Query: 62 VLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKA 121 VL AV ++N+ + P LL V +Q +D+ +IELDGTENK K GANAILGVS+A +A Sbjct: 64 VLTAVNNVNEIIAPELL--GFDVTEQNAIDQLLIELDGTENKGKLGANAILGVSMACARA 121 Query: 122 GAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEA 181 A +PLY++ L G LPVP N++NGG HA N + +QEFMI+PVGA +F+EA Sbjct: 122 AADFLQIPLYQY---LGGFNSKTLPVPMMNIVNGGEHADNNVDIQEFMIMPVGAPNFREA 178 Query: 182 MRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DK 239 +R+GA+++H LK V+ AK T VGDEGGFAPN+ N EAL+ + AI+ AG+ ++ Sbjct: 179 LRMGAQIFHSLKSVLSAK--GLNTAVGDEGGFAPNLGSNEEALQTIVEAIEKAGFKPGEE 236 Query: 240 VVIGMDVAASEFYR--NGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFD 297 V + MD A+SEFY +GKY L + + ++ + Y+ + YP++SIED D Sbjct: 237 VKLAMDAASSEFYNKEDGKYHLSGE-----GVVKTSAEMVDWYEELVSKYPIISIEDGLD 291 Query: 298 QDDWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQ 355 ++DW G +Q+VGDDL VTN K++++ ++ N +L+KVNQIG++TE+ Sbjct: 292 ENDWEGHKLLTERLGKKVQLVGDDLFVTNTKKLSEGIKNGVGNSILIKVNQIGTLTETFD 351 Query: 356 ACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEE 415 A ++A+ G+ ++SHRSGETED+ IAD+ V GQIKTGAP R++R+AKYNQL+RIE+ Sbjct: 352 AIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRVAKYNQLLRIED 411 Query: 416 ALGDKAVFAGRK-FRNP 431 L + A + G F N Sbjct: 412 QLAETAQYHGINSFYNL 428 >4MKS-A nrPDB Length = 440 Score = 639 bits (1650), Expect = 0.0, Method: Composition-based stats. Identities = 222/436 (50%), Positives = 289/436 (66%), Gaps = 16/436 (3%) Query: 2 AMQKIFAREILDSRGNPTVEVDLHTAKGRF-RAAVPSGASTGIYEALELRDGDKSRYLGK 60 + I ARE+LDSRGNPT E +++T G F RA VPSGASTG +EA+ELRDGDKSR+ G+ Sbjct: 3 VITDIHAREVLDSRGNPTAEAEVYTELGGFGRAIVPSGASTGEHEAVELRDGDKSRFGGQ 62 Query: 61 GVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 120 GVL AVE++N + A++ L V DQ +D+ MI+LDGT NK + GANAIL VSLA + Sbjct: 63 GVLTAVENVNGEIAKAVI--GLDVTDQRLIDQTMIDLDGTPNKGRLGANAILSVSLASAR 120 Query: 121 AGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 180 A A E G+PLY + L G VLP P NVINGG HA N + +QEFMI+PVGA S E Sbjct: 121 AAADELGLPLYEY---LGGPNAHVLPTPMMNVINGGKHADNNVDIQEFMIMPVGAKSLHE 177 Query: 181 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPD-- 238 A+R+GAE +H LKG+++ + ++T VGDEGGFAPN+ N E E+L AIQ AGY Sbjct: 178 AVRMGAETFHTLKGLLQER--GESTAVGDEGGFAPNLKNNEEPFEILVEAIQRAGYKPGQ 235 Query: 239 KVVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQ 298 + I D AASEFY D R + E+ L + + YPV+S+EDP D+ Sbjct: 236 DIAIAFDCAASEFYNK---DTKKYVTVADGREYTAEEWTSLIEDLVDKYPVISVEDPLDE 292 Query: 299 DDWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQA 356 +DW W +F G +QIVGDDL VTN + + ++ N +L+K+NQIG++TE+ +A Sbjct: 293 NDWEGWKTFTERLGDKVQIVGDDLFVTNTSYLEKGIKMGVANSILIKLNQIGTLTETFEA 352 Query: 357 CKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEA 416 ++A+ G+ +VSHRSGETEDT IADLVV GQIKTG+ R++R+AKYNQLMRIEEA Sbjct: 353 IEMAKEAGYTAVVSHRSGETEDTTIADLVVATNAGQIKTGSMSRTDRIAKYNQLMRIEEA 412 Query: 417 LGDKAVFAG-RKFRNP 431 LG A + G F N Sbjct: 413 LGSTAQYKGIHSFYNL 428 >3ZLH-A nrPDB Length = 455 Score = 639 bits (1649), Expect = 0.0, Method: Composition-based stats. Identities = 211/440 (47%), Positives = 293/440 (66%), Gaps = 17/440 (3%) Query: 2 AMQKIFAREILDSRGNPTVEVDLHTAKGRF-RAAVPSGASTGIYEALELRDGDKSRYLGK 60 + ++ARE+LDSRGNPT+EV+++T G F R VPSGASTG +EA+ELRDGDKSRYLG Sbjct: 23 IITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYLGL 82 Query: 61 GVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 120 G KAV+++N + A++ V DQ+ +D+ MI LDGT NK K GANAILGVS+AV + Sbjct: 83 GTQKAVDNVNNIIAKAII--GYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVAR 140 Query: 121 AGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 180 A A VPLY + L G VLP P N+INGGSH+ +A QEFMI+PVGA +FKE Sbjct: 141 AAADYLEVPLYTY---LGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMIMPVGAPTFKE 197 Query: 181 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--- 237 +R GAEV+H LK ++K + T VGDEGGFAP + +E + AI+AAGY Sbjct: 198 GLRWGAEVFHALKKILKER--GLVTAVGDEGGFAPKFEGTEDGVETILKAIEAAGYEAGE 255 Query: 238 DKVVIGMDVAASEFYRNGK--YDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDP 295 + ++IG D A+SEFY + YD + A S E++ + + + YP+++IED Sbjct: 256 NGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQV-DYLEELVNKYPIITIEDG 314 Query: 296 FDQDDWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTES 353 D++DW W G +Q+VGDD VTN + +A+ +++ A N +L+KVNQIG++TE+ Sbjct: 315 MDENDWDGWKVLTERLGKRVQLVGDDFFVTNTEYLARGIKENAANSILIKVNQIGTLTET 374 Query: 354 IQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRI 413 +A ++A+ G+ +VSHRSGETED+ IAD+ V GQIKTG+ R++R+AKYNQL+RI Sbjct: 375 FEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRI 434 Query: 414 EEALGDKAVFAG-RKFRNPK 432 E+ LG+ A + G + F N K Sbjct: 435 EDQLGEVAQYKGIKSFYNLK 454 >1W6T-A nrPDB Length = 444 Score = 636 bits (1641), Expect = 0.0, Method: Composition-based stats. Identities = 210/439 (47%), Positives = 291/439 (66%), Gaps = 16/439 (3%) Query: 2 AMQKIFAREILDSRGNPTVEVDLHTAKGRF-RAAVPSGASTGIYEALELRDGDKSRYLGK 60 + ++ARE+LDSRGNPT+EV+++T G F R VPSGASTG +EA+ELRDGDKSRY G Sbjct: 13 IITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYGGL 72 Query: 61 GVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 120 G KAV+++N + A++ V DQ+ +D+ MI LDGT NK K GANAILGVS+AV + Sbjct: 73 GTQKAVDNVNNIIAEAII--GYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVAR 130 Query: 121 AGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 180 A A +PLY + L G VLP P N+INGGSH+ +A QEFMILPVGA +FKE Sbjct: 131 AAADYLEIPLYSY---LGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMILPVGAPTFKE 187 Query: 181 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPD-- 238 A+R GAE++H LK ++K++ T VGDEGGFAP + +E + AI+AAGY Sbjct: 188 ALRYGAEIFHALKKILKSR--GLETAVGDEGGFAPRFEGTEDGVETILAAIEAAGYVPGK 245 Query: 239 KVVIGMDVAASEFYRNGK--YDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPF 296 V +G D A+SEFY + YD + A S E+ + + + YP+++IED Sbjct: 246 DVFLGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQ-IDYLEELVNKYPIITIEDGM 304 Query: 297 DQDDWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESI 354 D++DW W + G +Q+VGDD VTN +A+ +++ A N +L+KVNQIG++TE+ Sbjct: 305 DENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQEGAANSILIKVNQIGTLTETF 364 Query: 355 QACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIE 414 +A ++A+ G+ +VSHRSGETED+ IAD+ V GQIKTG+ R++R+AKYNQL+RIE Sbjct: 365 EAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIE 424 Query: 415 EALGDKAVFAG-RKFRNPK 432 + LG+ A + G + F N K Sbjct: 425 DQLGEVAEYRGLKSFYNLK 443 >2PA6-A nrPDB Length = 427 Score = 615 bits (1587), Expect = e-176, Method: Composition-based stats. Identities = 243/433 (56%), Positives = 311/433 (71%), Gaps = 15/433 (3%) Query: 1 MAMQKIFAREILDSRGNPTVEVDLHTAK-GRFRAAVPSGASTGIYEALELRDGDKSRYLG 59 ++ I ARE++DSRGNPTVEV++ T G A VPSGASTG +EALELRD +K R+ G Sbjct: 9 FEIKDIVAREVIDSRGNPTVEVEVITKGNGYGSAIVPSGASTGTHEALELRDKEK-RFGG 67 Query: 60 KGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVC 119 KGVL AVE++N + P +L Q ++D MIELDGT NKS+ GANAIL VSLAV Sbjct: 68 KGVLMAVENVNSIIRPEIL--GYDARMQREIDTIMIELDGTPNKSRLGANAILAVSLAVA 125 Query: 120 KAGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFK 179 KA AA +PLY++ L G V+PVP NVINGG HAGN L +QEFMI+PVGA+S Sbjct: 126 KAAAATAKIPLYKY---LGGFNSYVMPVPMMNVINGGKHAGNDLDLQEFMIMPVGATSIS 182 Query: 180 EAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDK 239 EA+R+G+EVYH LK VI KYGK+A NVGDEGGFAP + + EAL+LL +++ AGY D+ Sbjct: 183 EAVRMGSEVYHVLKNVILEKYGKNAVNVGDEGGFAPPLKTSREALDLLTESVKKAGYEDE 242 Query: 240 VVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQD 299 VV +D AASEFY++G Y ++ K ++ E+L + YK+ + YP+VSIEDPF ++ Sbjct: 243 VVFALDAAASEFYKDGYYYVEGK-------KLTREELLDYYKALVDEYPIVSIEDPFHEE 295 Query: 300 DWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKL 359 D+ + +DIQIVGDDL VTN +R+ + +E KA N LLLKVNQIG+++E++ A +L Sbjct: 296 DFEGFAMITKELDIQIVGDDLFVTNVERLRKGIEMKAANALLLKVNQIGTLSEAVDAAQL 355 Query: 360 AQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGD 419 A NG+GV+VSHRSGETEDT IADL V L +GQIKTGAP R ER AKYNQL+RIE+ LG Sbjct: 356 AFRNGYGVVVSHRSGETEDTTIADLSVALNSGQIKTGAPARGERTAKYNQLIRIEQELG- 414 Query: 420 KAVFAGRKFRNPK 432 + +AGR FR P Sbjct: 415 LSKYAGRNFRCPF 427 >4Z1Y-A nrPDB Length = 426 Score = 613 bits (1582), Expect = e-176, Method: Composition-based stats. Identities = 225/430 (52%), Positives = 298/430 (69%), Gaps = 17/430 (3%) Query: 3 MQKIFAREILDSRGNPTVEVDLHTAKG-RFRAAVPSGASTGIYEALELRDGDKSRYLGKG 61 ++ I ARE+LDSRGNPT+EVD+ G RA VPSGASTG +EALELRDGDKSRY GKG Sbjct: 5 IEAIVAREVLDSRGNPTIEVDVRLESGDVGRAIVPSGASTGAHEALELRDGDKSRYNGKG 64 Query: 62 VLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKA 121 VLKAV+ +N+ + AL+ DQ +D+ +I LDGT NKSK GANAILGVSLA KA Sbjct: 65 VLKAVQAVNEDIAEALI--GFDAADQIALDQELIALDGTPNKSKLGANAILGVSLAAAKA 122 Query: 122 GAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEA 181 AA G+PLYR++ + + VLPVP N++NGG HA N QEFMI+PVGA SF+E Sbjct: 123 AAAAFGLPLYRYLGGVYAH---VLPVPMMNIMNGGQHATNSTDFQEFMIMPVGAESFREG 179 Query: 182 MRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DK 239 +R GAE+YH LK VI + +T VGDEGGFAP++ N+ L+L+ AI+ AGY ++ Sbjct: 180 LRWGAEIYHMLKKVIHDR--GFSTTVGDEGGFAPSLPTNDAPLQLIMEAIEKAGYRPGEQ 237 Query: 240 VVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQD 299 +VI +D A +E + +GKY L + R +S ++ + + + YP++S+ED +D Sbjct: 238 IVIALDPATTEIFEDGKYHLKRE-----GRSLSSAEMVDYWVDLVNRYPIISLEDGLAED 292 Query: 300 DWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQAC 357 DW W + G +Q+VGDD VTN +R+ +A+E KA N +L+K+NQIGS+TE++ A Sbjct: 293 DWEGWALLRAKLGDRVQLVGDDFLVTNVQRLQRAIEAKAANSILIKLNQIGSLTETLSAI 352 Query: 358 KLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEAL 417 +LAQ +GW +VSHRSGE+ED IADLVV GQIKTGAP R++R+AKYNQL+RIEE L Sbjct: 353 QLAQRSGWTAVVSHRSGESEDVTIADLVVATNAGQIKTGAPARTDRIAKYNQLLRIEEEL 412 Query: 418 GDKAVFAGRK 427 G A +AGR Sbjct: 413 GSAARYAGRS 422 >5J04-A nrPDB Length = 425 Score = 610 bits (1573), Expect = e-175, Method: Composition-based stats. Identities = 232/435 (53%), Positives = 291/435 (66%), Gaps = 20/435 (4%) Query: 3 MQKIFAREILDSRGNPTVEVDLHTAKGRFR-AAVPSGASTGIYEALELRDGDKSRYLGKG 61 + +I AREILDSRG PTVE ++H G A VPSGASTG +EA ELRD D SRY GKG Sbjct: 5 IAEITAREILDSRGRPTVEAEVHLEDGSVGLAQVPSGASTGTFEAHELRDDDPSRYGGKG 64 Query: 62 VLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKA 121 V KAVE++ + AL+ LS +DQE +DK MI LDGT NK GANAIL VSLA A Sbjct: 65 VQKAVENV-SAIEDALI--GLSALDQEGLDKAMIALDGTPNKKNLGANAILAVSLATAHA 121 Query: 122 GAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEA 181 A +PLYR++ N VLPVP NVINGG+HA N + QEFMI+PVGA SFKEA Sbjct: 122 AATSLNLPLYRYLGGPLAN---VLPVPMMNVINGGAHADNNVDFQEFMIMPVGAPSFKEA 178 Query: 182 MRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DK 239 +R GAEV+H L V+K K AT VGDEGGFAPN+ N EALELL TAI+AAGY ++ Sbjct: 179 LRWGAEVFHALAKVLKDK--GLATGVGDEGGFAPNLGSNKEALELLLTAIEAAGYKPGEQ 236 Query: 240 VVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQD 299 V + MDVA+SEFY+NG Y D S + + + + YP+VSIED +D Sbjct: 237 VALAMDVASSEFYKNGLYTCDGVSHEPAG-------MIGILADLVSQYPIVSIEDGLQED 289 Query: 300 DWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQAC 357 DW+ W + G +Q+VGDDL VTNP R+ +E+ N +L+K+NQIG++TE+++ Sbjct: 290 DWSNWKTLTQQLGSTVQLVGDDLFVTNPDRLQSGIEQGVGNAVLIKLNQIGTLTETLRTI 349 Query: 358 KLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEAL 417 LA +G+ ++SHRSGETEDT IADL V GQIKTG+ RSER+AKYN+L+RIE AL Sbjct: 350 DLATRSGYRSVISHRSGETEDTTIADLAVATRAGQIKTGSLSRSERIAKYNRLLRIEAAL 409 Query: 418 GDKAVFAGRKFRNPK 432 G+ A++AG PK Sbjct: 410 GENALYAGAIGLGPK 424 >6NB2-A nrPDB Length = 430 Score = 604 bits (1559), Expect = e-173, Method: Composition-based stats. Identities = 212/428 (49%), Positives = 280/428 (65%), Gaps = 19/428 (4%) Query: 5 KIFAREILDSRGNPTVEVDLHTAKGRF-RAAVPSGASTGIYEALELRDGDKSRYLGKGVL 63 KI AREILDSRGNPT+E D+ G RA+VPSGASTG EA ELRD D RY GKGV Sbjct: 13 KIQAREILDSRGNPTIEADVTLTTGIIGRASVPSGASTGSREACELRDNDPKRYAGKGVQ 72 Query: 64 KAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGA 123 KAV+H+N + AL + LSV DQE +D+ + +LD TENKS GANAIL SLA +A A Sbjct: 73 KAVKHVNNEINQAL--QGLSVEDQENLDRILCQLDNTENKSHLGANAILATSLACARARA 130 Query: 124 AEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMR 183 PLY L + +PVP N++NGG+HA N + +QEFMI+P+GA F A++ Sbjct: 131 LSLNQPLY---MTLNQGDMMTMPVPMMNILNGGAHADNNVDIQEFMIMPIGAPDFPVALQ 187 Query: 184 IGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--DKVV 241 +G E++H LK V+K + T VGDEGGFAPNI N +AL+LL AI+ AG+ + +V Sbjct: 188 MGTEIFHVLKSVLKKQ--GLNTAVGDEGGFAPNIQSNRQALDLLSEAIEKAGFRLGEDIV 245 Query: 242 IGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDW 301 +DVAASE + G Y + ++ + +L E Y + I +YP+VSIED D+ DW Sbjct: 246 FALDVAASELFNEGFYHMYSEN-----QKFDSHQLIEYYANLISSYPIVSIEDGLDEKDW 300 Query: 302 ATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKL 359 + W + G +Q+VGDDL VTNPK + + + + N +L+KVNQIG+++E+ QA KL Sbjct: 301 SGWKQLTTHLGNKVQLVGDDLFVTNPKILREGIAQGIANAILIKVNQIGTLSETRQAIKL 360 Query: 360 AQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGD 419 A NG+ ++SHRSGETEDTFIADL V GQIKTG+ CR++R AKYNQL+RI E Sbjct: 361 AYDNGYRCVMSHRSGETEDTFIADLAVASGCGQIKTGSLCRTDRTAKYNQLLRINEL--A 418 Query: 420 KAVFAGRK 427 +AG+ Sbjct: 419 SLPYAGKN 426 >6BFZ-A nrPDB Length = 449 Score = 594 bits (1531), Expect = e-170, Method: Composition-based stats. Identities = 237/431 (54%), Positives = 297/431 (68%), Gaps = 14/431 (3%) Query: 3 MQKIFAREILDSRGNPTVEVDLHTAKGRFR-AAVPSGASTGIYEALELRDGDKSRYLGKG 61 + KI REI+DSRGNPTVE ++H G AA PSGASTG EALELRDGDKSR+LGKG Sbjct: 21 IVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKG 80 Query: 62 VLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKA 121 V KAV +N + AL+ K DQ +DK MI+LDGTENKSKFGANAIL VSLA KA Sbjct: 81 VTKAVAAVNGPIAQALIGK--DAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKA 138 Query: 122 GAAEKGVPLYRHIADLAGNP-DLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 180 AA KG+PLY HIA+L G P +PVP N+INGG HA N + +QEFMI PVGA + KE Sbjct: 139 AAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKE 198 Query: 181 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP--D 238 A+R+G+EV+HHL V+KAK T VGDEGG+APN+ N EAL ++ A++AAGY Sbjct: 199 AIRMGSEVFHHLAKVLKAK--GMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGK 256 Query: 239 KVVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQ 298 + + MD AASEFY++GKY L + + + E+ + K YP+VSIED D+ Sbjct: 257 DITLAMDCAASEFYKDGKYVL----AGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDE 312 Query: 299 DDWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQA 356 DW + G IQ+VGDDL VTN K + + +EK N +L+K NQIGS+TE++ A Sbjct: 313 SDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAA 372 Query: 357 CKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEA 416 K+A+ G+ ++SHRSGETED IADL VG GQIKTG+ RS+R+AKYNQL+RIEEA Sbjct: 373 IKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEA 432 Query: 417 LGDKAVFAGRK 427 LG+KA + GRK Sbjct: 433 LGEKAPYNGRK 443 >3TQP-A nrPDB Length = 428 Score = 593 bits (1528), Expect = e-170, Method: Composition-based stats. Identities = 210/431 (48%), Positives = 287/431 (66%), Gaps = 18/431 (4%) Query: 2 AMQKIFAREILDSRGNPTVEVDLHTAKGRFR-AAVPSGASTGIYEALELRDGDKSRYLGK 60 + I A EILDSR NPT+EV + + + AAVPSGASTG EA+ELRD D RY GK Sbjct: 4 TITDINAHEILDSRANPTLEVRVTLSSQAYGCAAVPSGASTGEREAVELRDNDLERYGGK 63 Query: 61 GVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 120 GVL+AVE++N + ALL + QE++D+ MIELDGTENK+ GANAILGVSLAV Sbjct: 64 GVLQAVENVNGPIRDALLGQ--DPRSQEEIDRIMIELDGTENKANLGANAILGVSLAVAY 121 Query: 121 AGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 180 A A +PLYR++ G +PVP N+INGG+HA N L QEFMI+PVGA +F E Sbjct: 122 AAANNADLPLYRYLGGDGG--PFSMPVPMMNIINGGAHATNNLDFQEFMIVPVGAPTFAE 179 Query: 181 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGY-PDK 239 A+R GAEV+H LK + ++ + VGDEGGFAP++ N A EL+ AI+ A Y P K Sbjct: 180 ALRYGAEVFHALKKRLVSR--GLMSAVGDEGGFAPDLPNNEAAFELILEAIEDANYVPGK 237 Query: 240 -VVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQ 298 + + +D A+SE Y+NG+YD + ++ E++ + + K YPV+SIED + Sbjct: 238 DIYLALDAASSELYQNGRYDFE-------NNQLTSEEMIDRLTEWTKKYPVISIEDGLSE 290 Query: 299 DDWATWTSFLSG--VDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQA 356 +DWA W +Q+VGDD+ VTNP + + ++K N +L+K+NQIG++TE++ Sbjct: 291 NDWAGWKLLTERLENKVQLVGDDIFVTNPDILEKGIKKNIANAILVKLNQIGTLTETLAT 350 Query: 357 CKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEA 416 LA+SN +GV++SHRSGETEDT IADL V QIKTG+ CRS+R+AKYN+L++IE Sbjct: 351 VGLAKSNKYGVIISHRSGETEDTTIADLAVATDARQIKTGSLCRSDRVAKYNRLLQIERE 410 Query: 417 LGDKAVFAGRK 427 L D+A +AG++ Sbjct: 411 LNDQAPYAGKE 421 >3UJ2-A nrPDB Length = 449 Score = 591 bits (1523), Expect = e-169, Method: Composition-based stats. Identities = 222/432 (51%), Positives = 297/432 (68%), Gaps = 19/432 (4%) Query: 1 MAMQKIFAREILDSRGNPTVEVDLHTAKGR-FRAAVPSGASTGIYEALELRDGDKSRYLG 59 + ++K+ REI+DSRGNPTVE +++ A G R PSGASTG +EALELRDGDK R+ G Sbjct: 26 LEIEKVIGREIIDSRGNPTVEAEVYLAGGVTGRGTAPSGASTGEFEALELRDGDKGRFGG 85 Query: 60 KGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVC 119 KGV KAV++IN + L + D VD+ MI+ DGT++KSKFGANA+L VS+A Sbjct: 86 KGVTKAVQNINTEISEIL--SGMDASDIYAVDRAMIDADGTKDKSKFGANAVLAVSIACA 143 Query: 120 KAGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFK 179 KA AA GVPLYR + L N LPVP N++NGG+HA N + +QEFMI+PVGA SF+ Sbjct: 144 KAAAAALGVPLYRFLGGLNANR---LPVPMMNILNGGAHAANTVDVQEFMIMPVGAESFR 200 Query: 180 EAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPD- 238 EA+R EV+H L G++K+K AT+VGDEGGFAP++ + EA+E + A++ AGY Sbjct: 201 EALRQCTEVFHALAGLLKSK--GLATSVGDEGGFAPDLASDEEAIEYILEAVKLAGYEPG 258 Query: 239 -KVVIGMDVAASEF--YRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDP 295 V+ MD A+SE+ + G+Y L R + E+L +KS + YP+VSIED Sbjct: 259 RDFVLAMDAASSEWKGEKKGEYILPK-----CKRKFASEELVAHWKSLCERYPIVSIEDG 313 Query: 296 FDQDDWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTES 353 D++DW W G IQ+VGDDL VTN +R+ + ++++ N +L+K+NQIG+V+E+ Sbjct: 314 LDEEDWEGWQYMTRELGDKIQLVGDDLFVTNTERLNKGIKERCGNSILIKLNQIGTVSET 373 Query: 354 IQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRI 413 ++A K+A G+ +VSHRSGETEDT IADL V L TGQIKTGAP RSER+AKYNQL+RI Sbjct: 374 LEAIKMAHKAGYTAVVSHRSGETEDTTIADLAVALNTGQIKTGAPSRSERVAKYNQLLRI 433 Query: 414 EEALGDKAVFAG 425 EE LGD AV+ G Sbjct: 434 EEELGDSAVYPG 445 >6O4N-A nrPDB Length = 432 Score = 586 bits (1510), Expect = e-168, Method: Composition-based stats. Identities = 218/439 (49%), Positives = 280/439 (63%), Gaps = 24/439 (5%) Query: 1 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFR-AAVPSGASTGIYEALELRDGDKSRYLG 59 + + I AREILDSRG PT+ V + T G F A VPSGASTGI EALELRD D RY G Sbjct: 12 VVISDIEAREILDSRGYPTLCVKVITNTGTFGEACVPSGASTGIKEALELRDKDPKRYQG 71 Query: 60 KGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVC 119 KGVL+A+ ++ K L PAL + SV DQ D MI+ DGT NK K GANAILGVSLA+ Sbjct: 72 KGVLQAISNVEKVLVPAL--QGFSVFDQITADAIMIDADGTPNKEKLGANAILGVSLALA 129 Query: 120 KAGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFK 179 KA A PLYR+ L G+ VLP P N+INGG HA N L QEFMI P+ A S K Sbjct: 130 KAAANTLQRPLYRY---LGGSFSHVLPCPMMNLINGGMHATNGLQFQEFMIRPISAPSLK 186 Query: 180 EAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYP-- 237 EA+R+GAEV++ LK +++ + + AT VGDEGGFAPN+ N EAL+LL TAI+ AG+ Sbjct: 187 EAVRMGAEVFNALKKILQNR--QLATGVGDEGGFAPNLASNAEALDLLLTAIETAGFTPR 244 Query: 238 DKVVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFD 297 + + + +D AAS FY D KS D + ++YP+ SIED Sbjct: 245 EDISLALDCAASSFYNTQDKTYDGKSYADQ---------VGILAELCEHYPIDSIEDGLA 295 Query: 298 QDDWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQ 355 ++D+ W G +Q+VGDDL VTN IA+ + + N +L+K NQIG++TE+ + Sbjct: 296 EEDFEGWKLLSETLGDRVQLVGDDLFVTNSALIAEGIAQGLANAVLIKPNQIGTLTETAE 355 Query: 356 ACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEE 415 A +LA G+ ++SHRSGETEDT IADL V TGQIKTG+ RSER+AKYN+LM IEE Sbjct: 356 AIRLATIQGYATILSHRSGETEDTTIADLAVAFNTGQIKTGSLSRSERIAKYNRLMAIEE 415 Query: 416 ALGDKAVFAGRKFRNPKAK 434 +G +A+F + NP +K Sbjct: 416 EMGPEALF---QDSNPFSK 431 >6J36-A nrPDB Length = 460 Score = 569 bits (1467), Expect = e-163, Method: Composition-based stats. Identities = 214/455 (47%), Positives = 291/455 (63%), Gaps = 32/455 (7%) Query: 3 MQKIFAREILDSRGNPTVEVDLHTAKGRFR-AAVPSGASTGIYEALELRDGDKS----RY 57 + K+FAREILDSRGNPT++VD++T G F A VPSGASTG EALELRD + Y Sbjct: 4 ITKVFAREILDSRGNPTIQVDVYTLAGGFGSAIVPSGASTGSREALELRDTNTKYADNWY 63 Query: 58 LGKGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLA 117 KGV+ AV+++N + P ++ L +Q +D+ +IELDGT NK K GANAILGVSLA Sbjct: 64 GQKGVMTAVDNVNNIIAPEII--GLCCKNQRLIDQKIIELDGTPNKEKLGANAILGVSLA 121 Query: 118 VCKAGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASS 177 V KA A E +PL+R+ L G ++PVP NVINGG HA N L QEFMI+P+G + Sbjct: 122 VAKAAANELRMPLFRY---LGGTNPTLMPVPMLNVINGGEHASNTLDFQEFMIMPLGFRT 178 Query: 178 FKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGY- 236 FKEA++ +V+H+L ++K K G + T VGDEGGFAPN + +AL+ L AI+ +G+ Sbjct: 179 FKEALQAANKVFHNLAKLLK-KSGFE-TQVGDEGGFAPNFNSHEQALDFLVDAIKESGFN 236 Query: 237 -----PDKVVIGMDVAASEFYRNGKYDLDFKSPD---------DPARHISGEKLGELYKS 282 + V I +D AASEFY KY D + E+L Y Sbjct: 237 PGFKGENAVAIAIDAAASEFYNGQKYVFKKLKAASLSKNQADLDEKFEFNSEELLNYYGQ 296 Query: 283 FIKNYPVVSIEDPFDQDDWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCL 340 + YP++SIED F + DW + +F G + QIVGDDLTVTN + + +A+ KA N + Sbjct: 297 LLAKYPIISIEDGFAESDWQGFIAFNQKYGNNHQIVGDDLTVTNVEILKKAINLKAINSI 356 Query: 341 LLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCR 400 L+K+NQIG+++E++ A LAQ +G ++SHRSGE+EDT IADL V + +GQIKTG+ R Sbjct: 357 LIKLNQIGTLSETLDAIHLAQKSGMTAVISHRSGESEDTTIADLAVAVSSGQIKTGSLSR 416 Query: 401 SERLAKYNQLMRIEEALGD--KAVFAGRK-FRNPK 432 ++R+AKYN+L+ IEE L KA + GR+ F N K Sbjct: 417 TDRIAKYNRLLVIEEYLNSYAKADYIGREVFYNLK 451 >3QN3-A nrPDB Length = 417 Score = 566 bits (1460), Expect = e-162, Method: Composition-based stats. Identities = 204/427 (47%), Positives = 278/427 (65%), Gaps = 22/427 (5%) Query: 1 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAA-VPSGASTGIYEALELRDGDKSRYLG 59 + ++ + A E+LDSRGNPTV+ ++ + G AA VPSGASTG EALELRD D+ R+ G Sbjct: 5 LVIEDVRAYEVLDSRGNPTVKAEVTLSDGSVGAAIVPSGASTGSKEALELRDNDE-RFGG 63 Query: 60 KGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVC 119 KGVLKAV ++N+T+ +L L +Q ++D + ELDGT N S GANA LGVS+A Sbjct: 64 KGVLKAVANVNETIADEIL--GLDAFNQTQLDDTLRELDGTNNYSNLGANATLGVSMATA 121 Query: 120 KAGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFK 179 +A AA G+PLYR+ L G +LPVP N+INGG+HA N + QEFMI+P G +SFK Sbjct: 122 RAAAAALGMPLYRY---LGGANASILPVPMCNIINGGAHANNNVDFQEFMIMPFGFTSFK 178 Query: 180 EAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDK 239 EA+R E+Y LK + +T +GDEGGFAPN+ N E ++LL T I+ AGY ++ Sbjct: 179 EALRSVCEIYAILKKELAN--SGHSTALGDEGGFAPNLANNTEPIDLLMTCIKKAGYENR 236 Query: 240 VVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQD 299 V I +DVA++EF+++GKY ++ K+ S E L E Y YP+ SIED ++ Sbjct: 237 VKIALDVASTEFFKDGKYHMEGKA-------FSSEALIERYVELCAKYPICSIEDGLAEN 289 Query: 300 DWATWTSFLS--GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQAC 357 D+ W G IQ+VGDDL VTN + + + KK N +L+K NQIG++T++++ Sbjct: 290 DFEGWIKLTEKLGNKIQLVGDDLFVTNEDILREGIIKKMANAVLIKPNQIGTITQTMRTV 349 Query: 358 KLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIE--- 414 +LAQ N + ++SHRSGE+ED FIAD V L TGQIKTGA R ER AKYN+L+ IE Sbjct: 350 RLAQRNNYKCVMSHRSGESEDAFIADFAVALNTGQIKTGALARGERTAKYNRLLEIEFES 409 Query: 415 -EALGDK 420 E LG+K Sbjct: 410 DEYLGEK 416 >4MMW-A nrPDB Length = 405 Score = 102 bits (255), Expect = 3e-22, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 39/78 (50%) Query: 292 IEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVT 351 IE+P D+ +++ +DI +VG + A+ ++ AC+ L VN +G +T Sbjct: 254 IEEPMDEQSLSSYKWLSDNLDIPVVGPESAAGKHWHRAEWIKAGACDILRTGVNDVGGIT 313 Query: 352 ESIQACKLAQSNGWGVMV 369 +++ LA++ G V Sbjct: 314 PALKTMHLAEAFGMECEV 331 >3R11-A nrPDB Length = 379 Score = 57.6 bits (138), Expect = 1e-08, Method: Composition-based stats. Identities = 47/206 (22%), Positives = 85/206 (41%), Gaps = 21/206 (10%) Query: 178 FKEAMRIGAEV-YHHL---------KGVIKAKYGKDATNVGDE-GGFAPNILENNEALEL 226 F A ++ ++ YH L ++ AK T+V G A I +E Sbjct: 97 FNSAAKMAIDLAYHDLLAKEQDISVAKLLGAKANSIVTDVSISCGNVAETIQNIQNGVEA 156 Query: 227 LKTAIQ---AAGYPDKVVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSF 283 TAI+ A + + + + +EF +N K+ D + A+ ++ E + Sbjct: 157 NFTAIKVKTGADFNRDIQL-LKALDNEFSKNIKFRFDANQGWNLAQ---TKQFIEEINKY 212 Query: 284 IKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLK 343 N + IE P D +I +V D+ V + K + ++++ACN + +K Sbjct: 213 SLNVEI--IEQPVKYYDIKAMAEITKFSNIPVVADES-VFDAKDAERVIDEQACNMINIK 269 Query: 344 VNQIGSVTESIQACKLAQSNGWGVMV 369 + + G + E+ + KLA S G MV Sbjct: 270 LAKTGGILEAQKIKKLADSAGISCMV 295 >4HNL-A nrPDB Length = 421 Score = 50.6 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 70/367 (19%), Positives = 126/367 (34%), Gaps = 74/367 (20%) Query: 2 AMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKG 61 + + + I R N V V + T KG G ST + L Sbjct: 27 IITDVKSFAIKPDRHNLVV-VKVETNKGISGL----GCSTFQFRPL-------------- 67 Query: 62 VLKAVEHI-NKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 120 AV+ + ++ L P L+ + + E + + M ++ NAI G+ +A+ Sbjct: 68 ---AVKTVVDEYLRPLLMGR--DANEIEDIWQVM-NVNSYWRNGPITNNAISGIDMALWD 121 Query: 121 AGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHA-GNKLAMQEFMILPVGASSFK 179 +PLY+ + A +PA+ +HA + L Sbjct: 122 IKGQLADMPLYQLLGGKARTA-----IPAY------THAVADNLD--------------- 155 Query: 180 EAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDK 239 ++YH + + A Y +G GG + E + + Y + Sbjct: 156 -------DLYHEIDRFLAAGYRYIRCQLGFYGGNPSQLQTPEEPIS--GSYFDQTDYME- 205 Query: 240 VVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIED--PFD 297 + M A E KY F+ D + + + K+ + Y + +ED P D Sbjct: 206 TTLKMFAAIKE-----KYGNQFQMLHDVHERLHPNQAIQFAKA-AEPYQLFFLEDILPPD 259 Query: 298 QDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQAC 357 Q W T S I +L NP + V+ + + + V+QIG +T +++ Sbjct: 260 QSHW--LTQLRSQSATPIATGELF-NNPMEWQELVKNRQIDFMRAHVSQIGGITPALKLA 316 Query: 358 KLAQSNG 364 + G Sbjct: 317 HFCDAMG 323 >3R25-A nrPDB Length = 401 Score = 47.9 bits (113), Expect = 7e-06, Method: Composition-based stats. Identities = 55/302 (18%), Positives = 107/302 (35%), Gaps = 48/302 (15%) Query: 65 AVEH-INKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGA 123 AV+ +++ L P L+ K + + E + + M+ ++ NAI GV +A+ A Sbjct: 48 AVKTMVDEYLKPILIGKNAN--NIEDLWQMMM-VNAYWRNGPVINNAISGVDMALWDIKA 104 Query: 124 AEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMR 183 G+PL++ G +PV +HA + E Sbjct: 105 KLAGMPLHQ---LFGGKSRDAIPV--------YTHATSDT---------------MEG-- 136 Query: 184 IGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIG 243 +Y ++G ++ Y +G GG ++ + + Y Sbjct: 137 ----IYDLVEGFLEKGYKHIRCQLGFYGGVPTDLHTTQNP-------TEGSYYDQDQY-- 183 Query: 244 MDVAASEFYR-NGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDWA 302 MD + F KY F D + + + K ++ Y IED + Sbjct: 184 MDNTLTMFKSLREKYGNQFHILHDVHERLFPNQAIQFAKE-VEQYKPYFIEDILPPNQTE 242 Query: 303 TWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQS 362 + S + + +L NP+ + + + + V+QIG +T +++ L Q+ Sbjct: 243 WLDNIRSQSSVSLGLGELF-NNPEEWKSLIANRRIDFIRCHVSQIGGITPALKLGHLCQN 301 Query: 363 NG 364 G Sbjct: 302 FG 303 >3QLD-A nrPDB Length = 388 Score = 47.2 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 31/155 (20%), Positives = 62/155 (40%), Gaps = 11/155 (7%) Query: 221 NEALELLKTAIQAA---GYPD---KVVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGE 274 +E+L++L ++ AA G+ K+ G D AA + R DL + + + Sbjct: 147 SESLDVLIQSVDAAVEQGFRRVKLKIAPGRDRAAIKAVRLRYPDLAIAADANGSYR---P 203 Query: 275 KLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEK 334 + + + Y + IE P +DDW + + + D+ V + + + Sbjct: 204 EDAPVLRQL-DAYDLQFIEQPLPEDDWFDLAKLQASLRTPVCLDES-VRSVRELKLTARL 261 Query: 335 KACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMV 369 A L +K ++G +++A +A G V Sbjct: 262 GAARVLNVKPGRLGGFGATLRALDVAGEAGMAAWV 296 >3S47-A nrPDB Length = 401 Score = 46.8 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 24/112 (21%), Positives = 43/112 (38%), Gaps = 6/112 (5%) Query: 255 GKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIED--PFDQDDWATWTSFLSGVD 312 KY F D + + + K ++ Y IED P DQ++W S Sbjct: 196 EKYGYKFHILHDVHERLFPNQAVQFAKD-VEKYKPYFIEDILPPDQNEWLG--QIRSQTS 252 Query: 313 IQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNG 364 + +L NP + + + + V+QIG +T +++ L + G Sbjct: 253 TPLATGELF-NNPMEWKSLIANRQVDFIRCHVSQIGGITPALKLGSLCAAFG 303 >4GIR-A nrPDB Length = 422 Score = 44.9 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 57/305 (18%), Positives = 106/305 (34%), Gaps = 54/305 (17%) Query: 65 AVEH-INKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGA 123 AV+ +++ L P L+ K + E + + M+ ++ NAI GV +A+ A Sbjct: 69 AVKTMVDEYLKPLLIGK--DANNIEDLWQMMM-VNAYWRNGPVINNAISGVDMALWDIKA 125 Query: 124 AEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMR 183 +PL++ + + V +HA + E + Sbjct: 126 KIANMPLHQLFGGKSRDAIQVY-----------THATSDT---------------MEGL- 158 Query: 184 IGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIG 243 Y + ++ Y +G GG NI Q + Y I Sbjct: 159 -----YEQVDKYLEQGYQHIRCQLGFYGGVPENIQTAQNP-------TQGSYYDQDQYIE 206 Query: 244 MDVAASEFYRN--GKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIED--PFDQD 299 V E ++N KY F D + + + K I+ Y IED P Q Sbjct: 207 NTV---EMFKNLREKYGKQFHILHDVHERLFPNQAIQFAKQ-IEQYNPFFIEDILPPSQT 262 Query: 300 DWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKL 359 +W + + + + +L NP+ + + + + V+QIG +T +++ Sbjct: 263 EW--LDNIRNQSSVSLALGELF-NNPEEWKALIINRRVDFIRCHVSQIGGITPALKLGHF 319 Query: 360 AQSNG 364 +S G Sbjct: 320 CESFG 324 >2GGG-A nrPDB Length = 375 Score = 43.7 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 38/163 (23%), Positives = 65/163 (39%), Gaps = 18/163 (11%) Query: 210 EGGFAPNILENNEA-LELLKTAIQAAGYPD---KVVIGMDV----AASEFYRNGKYDLDF 261 E G + I + +A ++L++ ++ GY K+ G DV A E + + + +D Sbjct: 138 EVGVSLGIQADEQATVDLVRRHVEQ-GYRRIKLKIKPGWDVQPVRATREAFPDIRLTVDA 196 Query: 262 KSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLT 321 S A +L E Y + IE P DD + + D+ Sbjct: 197 NSAYTLADAGRLRQLDE--------YDLTYIEQPLAWDDLVDHAELARRIRTPLCLDES- 247 Query: 322 VTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNG 364 V + +A+ A + LKV ++G ES + +AQS G Sbjct: 248 VASASDARKALALGAGGVINLKVARVGGHAESRRVHDVAQSFG 290 >1WUE-A nrPDB Length = 386 Score = 43.7 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 37/80 (46%), Gaps = 1/80 (1%) Query: 284 IKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLK 343 + +Y + IE PF DD+ + +I D+ + + K A+ +C + LK Sbjct: 224 LDHYQLAMIEQPFAADDFLDHAQLQRELKTRICLDE-NIRSLKDCQVALALGSCRSINLK 282 Query: 344 VNQIGSVTESIQACKLAQSN 363 + ++G + E+++ Q N Sbjct: 283 IPRVGGIHEALKIAAFCQEN 302 >3JW7-A nrPDB Length = 354 Score = 43.3 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 20/118 (16%), Positives = 51/118 (43%), Gaps = 2/118 (1%) Query: 259 LDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGD 318 D K D + + + + ++ +Y + +E P + D S V+ I+ D Sbjct: 182 FDIKLRLDANQAWTPKDAVKAIQAL-ADYQIELVEQPVKRRDLEGLKYVTSQVNTTIMAD 240 Query: 319 DLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGET 376 + + + V+K + + +K+ + G + E+++ ++ ++ G M+ + ET Sbjct: 241 ESCFDAQDAL-ELVKKGTVDVINIKLMKCGGIHEALKINQICETAGIECMIGCMAEET 297 >1TKK-A nrPDB Length = 366 Score = 43.3 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 39/78 (50%), Gaps = 1/78 (1%) Query: 292 IEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVT 351 +E P +DD A D I+ D+ T P++ + ++ ++ + + +K+ + G ++ Sbjct: 218 VEQPVHKDDLAGLKKVTDATDTPIMADESVFT-PRQAFEVLQTRSADLINIKLMKAGGIS 276 Query: 352 ESIQACKLAQSNGWGVMV 369 + + +A++ G MV Sbjct: 277 GAEKINAMAEACGVECMV 294 >3IK4-A nrPDB Length = 365 Score = 42.9 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 38/82 (46%), Gaps = 2/82 (2%) Query: 288 PVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQI 347 P+V E P ++DWA + + D+ + + A + + + +K+ + Sbjct: 216 PMVLFEQPLPREDWAGMAQVTAQSGFAVAADESARSAHDVLRIA-REGTASVINIKLMKA 274 Query: 348 GSVTESIQACKLAQSNGWGVMV 369 G V E ++ +AQ+ G G+M+ Sbjct: 275 G-VAEGLKMIAIAQAAGLGLMI 295 >2ZC8-A nrPDB Length = 369 Score = 42.2 bits (98), Expect = 5e-04, Method: Composition-based stats. Identities = 38/168 (22%), Positives = 59/168 (35%), Gaps = 20/168 (11%) Query: 204 ATNVGDEGGFAPNILENNEALELLKTAIQAAGYPD---KVVIGMDV----AASEFYRNGK 256 A VG G P++ + +E GY K+ G D A E + Sbjct: 129 AVEVGVSLGIQPSVEDTLRVVERHLE----EGYRRIKLKIKPGWDYEVLKAVREAFPEAT 184 Query: 257 YDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIV 316 D S A ++L EL + IE P DD + I Sbjct: 185 LTADANSAYSLANLAQLKRLDELRLDY--------IEQPLAYDDLLDHAKLQRELSTPIC 236 Query: 317 GDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNG 364 D+ T ++ +A+E A +K ++G ES++ LA+S G Sbjct: 237 LDESL-TGAEKARKAIELGAGRVFNVKPARLGGHGESLRVHALAESAG 283 >2QDE-A nrPDB Length = 397 Score = 40.6 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 39/190 (20%), Positives = 64/190 (33%), Gaps = 16/190 (8%) Query: 183 RIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQ----AAGYPD 238 R G VY L G + G EAL +L+ AG P Sbjct: 118 RFGVPVYQLLGGKTIERIPLGLVL-----GAGEPEAVAEEALAVLREGFHFVKLKAGGPL 172 Query: 239 KVVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQ 298 K I M +E R D+D D + ++ ++ + Y + IE P Sbjct: 173 KADIAM---VAEVRRAVGDDVDLFI--DINGAWTYDQALTTIRAL-EKYNLSKIEQPLPA 226 Query: 299 DDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACK 358 D V I D+ +A + K A + L++K + G + ++ + Sbjct: 227 WDLDGMARLRGKVATPIYADESAQELHDLLAI-INKGAADGLMIKTQKAGGLLKAQRWLT 285 Query: 359 LAQSNGWGVM 368 LA+ V+ Sbjct: 286 LARLANLPVI 295 >3TJI-A nrPDB Length = 422 Score = 39.5 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 52/303 (17%), Positives = 98/303 (32%), Gaps = 50/303 (16%) Query: 65 AVEH-INKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGA 123 AV+ +++ L P ++ + + E + + M ++ NAI GV +A+ Sbjct: 69 AVKTLVDEYLQPLMIGR--DANNIEDLWQMM-NVNAYWRNGPLMNNAISGVDMALWDIKG 125 Query: 124 AEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMR 183 G+PLY+ G +P SHA + EA+ Sbjct: 126 QLAGMPLYQ---LFGGKSRDAIP--------AYSHASGET---------------LEAL- 158 Query: 184 IGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIG 243 + + +I Y +G GG + + A + + + Sbjct: 159 -----FASVDALIAQGYRHIRCQLGFYGGTPSALHAPDNPTP-------GAWFDQQEYMS 206 Query: 244 MDVAASEFYR--NGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDW 301 V E + KY D + ++ +L K P IED Sbjct: 207 NTV---EMFHALREKYGWKLHILHDVHERLFPQQAVQLAKQLEPFQPYF-IEDILPPQQS 262 Query: 302 ATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQ 361 A + + +L NP + + + + V+QIG +T +++ L Q Sbjct: 263 AWLEQVRQQSCVPLALGELF-NNPAEWHDLIVNRRIDFIRCHVSQIGGITPALKLAHLCQ 321 Query: 362 SNG 364 + G Sbjct: 322 AFG 324 >3Q4D-A nrPDB Length = 368 Score = 39.5 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 43/104 (41%), Gaps = 2/104 (1%) Query: 266 DPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNP 325 D + S E E ++ Y + E+P ++ + I I+ D+ N Sbjct: 190 DANQGWSVETAIETLT-LLEPYNIQHCEEPVSRNLYTALPKIRQACRIPIMADES-CCNS 247 Query: 326 KRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMV 369 + ++ +AC+ LK+++ +T ++ +LA+ V V Sbjct: 248 FDAERLIQIQACDSFNLKLSKSAGITNALNIIRLAEQAHMPVQV 291 >3UGV-A nrPDB Length = 390 Score = 39.1 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 51/262 (19%), Positives = 95/262 (36%), Gaps = 64/262 (24%) Query: 110 AILGVSLAVCKAGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFM 169 A GV +AV A A +PL + G+ V A+N N L ++ Sbjct: 127 AASGVDMAVWDALARAANMPLCTLLGGTPGS------VKAYN--------SNGLWLKS-- 170 Query: 170 ILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKT 229 A EA+ + AE +K + G+D V +I + Sbjct: 171 ----PAEVAAEAVELKAEGQGTGFKGLKLRMGRDDPAV--------DIETAEAVWD---- 214 Query: 230 AIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPV 289 +G D A + G LD R ++ +L + Sbjct: 215 -----------AVGRDTALMVDFNQG---LDMAEAMHRTR-----QIDDLGLEW------ 249 Query: 290 VSIEDPFDQDDWATWTSFLSGVDIQI-VGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIG 348 IE+P D++ + + + +G++ P+ + QA++ AC+ ++ +IG Sbjct: 250 --IEEPVVYDNFDGYAQLRHDLKTPLMIGENFY--GPREMHQALQAGACDLVMPDFMRIG 305 Query: 349 SVTESIQACKLAQSNGWGVMVS 370 V+ ++A +A + WG+ +S Sbjct: 306 GVSGWMRAAGVAGA--WGIPMS 325 >5FJT-A nrPDB Length = 368 Score = 38.3 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 32/73 (43%), Gaps = 1/73 (1%) Query: 292 IEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVT 351 IE P +++D + I D+ V+ + A A++ A + +K ++G Sbjct: 213 IEQPLEEEDVLGHAELARRIQTPICLDESIVS-ARAAADAIKLGAVQIVNIKPGRVGGYL 271 Query: 352 ESIQACKLAQSNG 364 E+ + + ++G Sbjct: 272 EARRVHDVCAAHG 284 >3IJQ-A nrPDB Length = 338 Score = 38.3 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 25/132 (18%), Positives = 47/132 (35%), Gaps = 6/132 (4%) Query: 239 KVVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQ 298 KV +G D E + D D + + ++K +V IE P + Sbjct: 153 KVKLGRD-NDKEMIETIRSVTDLPIAVDANQGWKDRQYALDMIHWLKEKGIVMIEQPMPK 211 Query: 299 DDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQ-AVEKKACNCLLLKVNQIGSVTESIQAC 357 + + + D+ +R+ A K A + +K+ + + E+ + Sbjct: 212 EQLDDIAWVTQQSPLPVFADESL----QRLGDVAALKGAFTGINIKLMKCTGMREAWKMV 267 Query: 358 KLAQSNGWGVMV 369 LA + G VMV Sbjct: 268 TLAHALGMRVMV 279 >1WUF-A nrPDB Length = 393 Score = 37.5 bits (86), Expect = 0.012, Method: Composition-based stats. Identities = 30/154 (19%), Positives = 59/154 (38%), Gaps = 6/154 (3%) Query: 212 GFAPNILENNEALELLKTAIQAAGYPD-KVVIGMDVAASEFYRNGKYDLDFKS-PDDPAR 269 G + + +N E L L GY K+ I + +F + S D Sbjct: 153 GVSIGLQQNVETLLQLVNQYVDQGYERVKLKIAPN-KDIQFVEAVRKSFPKLSLMADANS 211 Query: 270 HISGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIA 329 + E L + + Y + IE PF D+ + +I D+ + + K + Sbjct: 212 AYNREDFLLLKE--LDQYDLEMIEQPFGTKDFVDHAWLQKQLKTRICLDE-NIRSVKDVE 268 Query: 330 QAVEKKACNCLLLKVNQIGSVTESIQACKLAQSN 363 QA +C + LK+ ++G ++ +++ + N Sbjct: 269 QAHSIGSCRAINLKLARVGGMSSALKIAEYCALN 302 >3UXL-A nrPDB Length = 383 Score = 37.2 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 4/81 (4%) Query: 292 IEDPFDQDDWATWTSFLSGVDIQI-VGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSV 350 IE+P Q D+ S +++ + +G++ P+ + +A+ AC + +IG V Sbjct: 244 IEEPTLQHDYEGHQRIQSKLNVPVQMGENWL--GPEEMFKALSIGACRLAMPDAMKIGGV 301 Query: 351 TESIQACKLAQSNGWGVMVSH 371 T I+A LAQ G M SH Sbjct: 302 TGWIRASALAQQFGIP-MSSH 321 >5X3E-A nrPDB Length = 449 Score = 36.8 bits (84), Expect = 0.019, Method: Composition-based stats. Identities = 23/86 (26%), Positives = 39/86 (45%), Gaps = 2/86 (2%) Query: 214 APNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDL--DFKSPDDPARHI 271 A + + E + AI+ +GY D +V + V E Y N YDL D ++ R I Sbjct: 187 ADRLSTSREITDRYCEAIKLSGYNDDMVCSVFVTYVEIYNNYCYDLLEDARNGVLTKREI 246 Query: 272 SGEKLGELYKSFIKNYPVVSIEDPFD 297 ++ ++Y K+ V S E+ + Sbjct: 247 RHDRQQQMYVDGAKDVEVSSSEEALE 272 >3I4K-A nrPDB Length = 383 Score = 36.0 bits (82), Expect = 0.030, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 34/75 (45%), Gaps = 1/75 (1%) Query: 293 EDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTE 352 E P DD T ++ ++ D+ T + +A V+ +A + + LK + G + E Sbjct: 226 EQPTPADDLETLREITRRTNVSVMADESVWTPAEALAV-VKAQAADVIALKTTKHGGLLE 284 Query: 353 SIQACKLAQSNGWGV 367 S + +A++ G Sbjct: 285 SKKIAAIAEAGGLAC 299 >2OG9-A nrPDB Length = 393 Score = 36.0 bits (82), Expect = 0.030, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 33/78 (42%), Gaps = 1/78 (1%) Query: 287 YPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQ 346 + +V IE+P D D + D I ++ + + + +A + L+ + Sbjct: 233 FNLVWIEEPLDAYDHEGHAALALQFDTPIATGEMLTSAAEH-GDLIRHRAADYLMPDAPR 291 Query: 347 IGSVTESIQACKLAQSNG 364 +G +T ++ LA+ G Sbjct: 292 VGGITPFLKIASLAEHAG 309 >2PP0-A nrPDB Length = 398 Score = 36.0 bits (82), Expect = 0.031, Method: Composition-based stats. Identities = 13/81 (16%), Positives = 35/81 (43%), Gaps = 1/81 (1%) Query: 284 IKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLK 343 ++ + ++ IE+P D D + +D I ++ + + Q + A + + Sbjct: 243 MEQFNLIWIEEPLDAYDIEGHAQLAAALDTPIATGEMLTSFREH-EQLILGNASDFVQPD 301 Query: 344 VNQIGSVTESIQACKLAQSNG 364 ++G ++ ++ LA +G Sbjct: 302 APRVGGISPFLKIMDLAAKHG 322 >3I6E-A nrPDB Length = 385 Score = 35.6 bits (81), Expect = 0.041, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Query: 292 IEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVT 351 IE P + D+ ++ D+ V P+ + +A + C+ + +K+ + G +T Sbjct: 223 IEQPVRAHHFELMARLRGLTDVPLLADES-VYGPEDMVRAAHEGICDGVSIKIMKSGGLT 281 Query: 352 ESIQACKLAQSNG 364 + ++A ++G Sbjct: 282 RAQTVARIAAAHG 294 >3TW9-A nrPDB Length = 442 Score = 35.6 bits (81), Expect = 0.042, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 32/81 (39%), Gaps = 1/81 (1%) Query: 284 IKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLK 343 ++ Y + +EDP ++ I +L V N ++ + + + Sbjct: 265 LEQYQLFYLEDPVAPENIDWLKMLRQQSSTPISMGELFV-NVNEWKPLIDNRLIDYIRCH 323 Query: 344 VNQIGSVTESIQACKLAQSNG 364 V+ IG +T + + ++ NG Sbjct: 324 VSTIGGITPARKLAVYSELNG 344 >2PGW-A nrPDB Length = 384 Score = 35.2 bits (80), Expect = 0.050, Method: Composition-based stats. Identities = 23/105 (21%), Positives = 44/105 (41%), Gaps = 2/105 (1%) Query: 284 IKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLK 343 ++ Y + IE P V I IV D T + + ++A + + + Sbjct: 213 LEKYDIEFIEQPTVSWSIPAMAHVREKVGIPIVADQAAFTLYD-VYEICRQRAADMICIG 271 Query: 344 VNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGL 388 +IG + ++A +A++ G + + H S T T A+ +GL Sbjct: 272 PREIGGIQPMMKAAAVAEAAGLKICI-HSSFTTGITTCAEHHIGL 315 >3T6C-A nrPDB Length = 440 Score = 35.2 bits (80), Expect = 0.052, Method: Composition-based stats. Identities = 17/100 (17%), Positives = 37/100 (37%), Gaps = 2/100 (2%) Query: 265 DDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTN 324 D I+ + K+ + Y + +EDP ++ I +L V N Sbjct: 245 HDAHERITPINAIHMAKAL-EPYQLFFLEDPVAPENTEWLKMLRQQSSTPIAMGELFV-N 302 Query: 325 PKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNG 364 ++ K + + ++ IG +T + + ++ NG Sbjct: 303 VNEWKPLIDNKLIDYIRCHISSIGGITPAKKIAIYSELNG 342 >2P8B-A nrPDB Length = 369 Score = 35.2 bits (80), Expect = 0.060, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 37/81 (45%), Gaps = 1/81 (1%) Query: 289 VVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIG 348 + IE P DD S D+ ++ D+ ++ + + Q ++ +A + + +K+ + G Sbjct: 214 IDWIEQPVIADDIDAMAHIRSKTDLPLMIDEGLKSSRE-MRQIIKLEAADKVNIKLMKCG 272 Query: 349 SVTESIQACKLAQSNGWGVMV 369 + +++ A+ G V Sbjct: 273 GIYPAVKLAHQAEMAGIECQV 293 >3MWC-A nrPDB Length = 400 Score = 34.8 bits (79), Expect = 0.073, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 33/73 (45%), Gaps = 3/73 (4%) Query: 293 EDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEK-KACNCLLLKVNQIGSVT 351 E P + ++ I D+ ++ R+A+ V K N +K+ ++G + Sbjct: 236 EQPLHYEALLDLKELGERIETPICLDESLIS--SRVAEFVAKLGISNIWNIKIQRVGGLL 293 Query: 352 ESIQACKLAQSNG 364 E+I+ K+A NG Sbjct: 294 EAIKIYKIATDNG 306 >3SJN-A nrPDB Length = 374 Score = 34.8 bits (79), Expect = 0.080, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 34/80 (42%), Gaps = 2/80 (2%) Query: 292 IEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVT 351 IE+P D ++ V +I G + T + + + K + + + + G +T Sbjct: 225 IEEPVLADSLISYEKLSRQVSQKIAGGESLTTRYE-FQEFITKSNADIVQPDITRCGGIT 283 Query: 352 ESIQACKLAQSNGWGVMVSH 371 E + +AQ NG ++ H Sbjct: 284 EMKKIYDIAQMNG-TQLIPH 302 >3U9I-A nrPDB Length = 393 Score = 34.5 bits (78), Expect = 0.10, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 33/79 (41%), Gaps = 6/79 (7%) Query: 293 EDPFDQDDWATWTSFLSGVDIQIVGDDL--TVTNPKRIAQAVEKKACNCLLLKVNQIGSV 350 E P +DD + + + D+ + T+ R+A+ N L+K + Sbjct: 251 EQPVAKDDEEGLRRLTATRRVPVAADESVASATDAARLARNAAVDVLNIKLMKC----GI 306 Query: 351 TESIQACKLAQSNGWGVMV 369 E++ +A++ G +M+ Sbjct: 307 VEALDIAAIARTAGLHLMI 325 >4MGG-A nrPDB Length = 369 Score = 34.1 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 25/97 (25%), Positives = 44/97 (45%), Gaps = 15/97 (15%) Query: 319 DLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNG--------WG---- 366 D + P + + + + A +C+ LK++++G +T++ L ++G WG Sbjct: 243 DEVIDGPNTLVRGIAEDAMDCINLKISKVGGLTKAKLMRDLCIAHGIPMTIEDTWGGDIV 302 Query: 367 -VMVSH--RSGETEDTFIADLVVGLCTGQIKTGAPCR 400 ++H RS +E TF A T I GAP R Sbjct: 303 TAAIAHLARSTPSEFTFSATDFNSYGTVDIAEGAPKR 339 >4IHC-A nrPDB Length = 440 Score = 33.7 bits (76), Expect = 0.18, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 32/81 (39%), Gaps = 1/81 (1%) Query: 284 IKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLK 343 ++ Y + +EDP ++ I +L V N ++ K + + Sbjct: 263 LEPYQLFYLEDPVAPENIDWLRMLRQQSSTPISMGELFV-NINEWKPLIDNKLIDYIRCH 321 Query: 344 VNQIGSVTESIQACKLAQSNG 364 V+ IG +T + + ++ NG Sbjct: 322 VSTIGGITPAKKLAVYSELNG 342 >3K4W-A nrPDB Length = 291 Score = 33.3 bits (75), Expect = 0.20, Method: Composition-based stats. Identities = 32/144 (22%), Positives = 51/144 (35%), Gaps = 29/144 (20%) Query: 212 GFAPNILENNEALELLKTAIQAAGYPDKVVIG-----------MDVAASEFYRNGKYDLD 260 GF P ++LEL+ + AAG V +G DVAA Y Sbjct: 37 GFEPAPSAEEKSLELMFEEMAAAGIEQGVCVGRNSSVLGSVSNADVAAV----AKAYPDK 92 Query: 261 FKSPDDPARHISGEKLGELYKSFIKNYPVVSIE-----DPFDQDDWATWT--SFLSGVDI 313 F E + ++ + +V++E P DD + +F I Sbjct: 93 FHPVGSIEAATRKEAMAQMQEILDLGIRIVNLEPGVWATPMHVDDRRLYPLYAFCEDNGI 152 Query: 314 QIV-------GDDLTVTNPKRIAQ 330 ++ G D+T TNP+ I + Sbjct: 153 PVIMMTGGNAGPDITYTNPEHIDR 176 >3S5S-A nrPDB Length = 389 Score = 33.3 bits (75), Expect = 0.20, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 35/80 (43%), Gaps = 6/80 (7%) Query: 292 IEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKA--CNCLLLKVNQIGS 349 +E P +DDW + + D+ + + A E+ A N L+K G Sbjct: 221 LEQPVPRDDWDGMKEVTRRAGVDVAADESAASAEDVLRVAAERAATVVNIKLMK----GG 276 Query: 350 VTESIQACKLAQSNGWGVMV 369 + E++ +A++ G G+M+ Sbjct: 277 IAEALDIAAVARAAGLGLMI 296 >1NU5-A nrPDB Length = 370 Score = 33.3 bits (75), Expect = 0.20, Method: Composition-based stats. Identities = 16/109 (14%), Positives = 42/109 (38%), Gaps = 5/109 (4%) Query: 274 EKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVE 333 E+ ++ ++ V +E P + ++ + I+ D+ + A Sbjct: 201 EQTASIWIPRLEEAGVELVEQPVPRANFGALRRLTEQNGVAILADESLSSLSSAFELA-R 259 Query: 334 KKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIA 382 A + LK+ +G + +++ +A++ G +S G D+ + Sbjct: 260 DHAVDAFSLKLCNMGGIANTLKVAAVAEAAG----ISSYGGTMLDSTVG 304 >4PG8-A nrPDB Length = 468 Score = 33.3 bits (75), Expect = 0.21, Method: Composition-based stats. Identities = 40/134 (29%), Positives = 59/134 (44%), Gaps = 17/134 (12%) Query: 49 LRDGDKSRYLGKGVLKAVEHINKTLGPALLEKKLSVVD--QEKVDKFMIELDGTENKSK- 105 +RD K R L E +N+ L L+ + V+ + VD L +NK Sbjct: 64 VRDKSKKRPLNISQYHLTEDVNEILNDDSLDIIVEVMGGIEPTVDWLRTAL---KNKKHV 120 Query: 106 FGANA-ILGVSLAVCKAGAAEKGVPLYRHIADLAGNPDLVLPVPAFNVINGGSHAGNKLA 164 AN +L V L + + A E GV L + A +AG +P N IN G +A N Sbjct: 121 ITANKDLLAVHLKLLEDLAEENGVAL-KFEASVAGG------IPIVNAINNGLNANN--- 170 Query: 165 MQEFMILPVGASSF 178 + +FM + G S+F Sbjct: 171 ISKFMGILNGTSNF 184 >3G68-A nrPDB Length = 352 Score = 33.3 bits (75), Expect = 0.23, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 38/76 (50%), Gaps = 4/76 (5%) Query: 338 NCLLLKVNQIGSVTESIQACKLAQSNG--WGVMVSHRSGETEDTFIADLVVGLCTGQIKT 395 N L++ V+Q GS + A KLA+ G M ++ ++ I+D ++ + G+ K+ Sbjct: 83 NTLVVGVSQGGSSYSTYNAMKLAEDKGCKIASMAGCKNALIDE--ISDYILTVNCGEEKS 140 Query: 396 GAPCRSERLAKYNQLM 411 GA + K N ++ Sbjct: 141 GAKTKGYYCTKLNLML 156 >3EKG-A nrPDB Length = 404 Score = 32.2 bits (72), Expect = 0.42, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 35/91 (38%), Gaps = 4/91 (4%) Query: 285 KNYPVVSIEDPFDQDDWATWTSFLSG--VDIQIVGDDLTVTNPKRIAQAVEKKACNCLLL 342 + Y + IE+ DD+ + + + + T +E C+ + Sbjct: 234 REYGLKWIEEALPPDDYWGYAELRRNAPTGMMVTTGEHEATR-WGFRMLLEMGCCDIIQP 292 Query: 343 KVNQIGSVTESIQACKLAQSNGWGVMVSHRS 373 V G VTE ++ LA ++ ++V H S Sbjct: 293 DVGWCGGVTELLKISALADAHN-ALVVPHGS 322 >2CHR-A nrPDB Length = 370 Score = 32.2 bits (72), Expect = 0.42, Method: Composition-based stats. Identities = 19/109 (17%), Positives = 45/109 (41%), Gaps = 5/109 (4%) Query: 274 EKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVE 333 E++ +Y ++ V IE P +++ + I+ D+ T A Sbjct: 201 EQVASVYIPELEALGVELIEQPVGRENTQALRRLSDNNRVAIMADESLSTLASAFDLA-R 259 Query: 334 KKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIA 382 ++ + LK+ +G V+ + + +A+++G ++ G D+ I Sbjct: 260 DRSVDVFSLKLCNMGGVSATQKIAAVAEASG----IASYGGTMLDSTIG 304 >3TTE-A nrPDB Length = 383 Score = 32.2 bits (72), Expect = 0.43, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 41/89 (46%), Gaps = 4/89 (4%) Query: 284 IKNYPVVSIEDPFDQDDWATWTSFLSGVDIQI-VGDDLTVTNPKRIAQAVEKKACNCLLL 342 + +Y + IE+P Q++ + + +I I G++ P+ A+A+ A + ++ Sbjct: 236 LADYDLTWIEEPVPQENLSGHAAVRERSEIPIQAGENWWF--PRGFAEAIAAGASDFIMP 293 Query: 343 KVNQIGSVTESIQACKLAQSNGWGVMVSH 371 + ++G +T + A + M SH Sbjct: 294 DLMKVGGITGWLNVAGQADAASIP-MSSH 321 >2Z8X-A nrPDB Length = 617 Score = 32.2 bits (72), Expect = 0.52, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 42/110 (38%), Gaps = 20/110 (18%) Query: 178 FKEAMRIGAEVYHHLKGVIKAKYGKDATNVG-------------DEGGFAPNILENNEAL 224 F +AM I YH+L A Y + +G D G P I N ++ Sbjct: 18 FSDAMAITLYSYHNLDNGFAAGYQHNGFGLGLPATLVTALLGGTDSQGVIPGIPWNPDSE 77 Query: 225 ELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSPDDPARHISGE 274 +L A++ AG+ + AS+ +GK D + A + + + Sbjct: 78 KLALDAVKKAGWTP-------ITASQLGYDGKTDARGTFFGEKAGYTTAQ 120 >3RO6-B nrPDB Length = 356 Score = 31.8 bits (71), Expect = 0.57, Method: Composition-based stats. Identities = 24/113 (21%), Positives = 44/113 (38%), Gaps = 9/113 (7%) Query: 266 DPARHISGEKLGELYKSFIKNYPVVSIEDPF--DQDDWATWTSFLSGVDIQIVGDDLTVT 323 DP + + L L ++ + IE PF + DW + + +I D+ + Sbjct: 190 DPNQSYDRDGLLRL-DRLVQELGIEFIEQPFPAGRTDW--LRALPKAIRRRIAADESLLG 246 Query: 324 NPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNG----WGVMVSHR 372 A A AC +K+ + G + + + +A++ G WG M R Sbjct: 247 PADAFALAAPPAACGIFNIKLMKCGGLAPARRIATIAETAGIDLMWGCMDESR 299 >3ERV-A nrPDB Length = 236 Score = 31.8 bits (71), Expect = 0.67, Method: Composition-based stats. Identities = 21/68 (30%), Positives = 33/68 (48%), Gaps = 6/68 (8%) Query: 252 YRNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIED----PFDQDDWATWTSF 307 Y + L K + A ++G+ + ELYKS PVV I + P D+D++ TW Sbjct: 108 YHGPLFQLAKKYLPNKAVDLTGKSIEELYKSVKAGQPVVIITNATFAPLDEDEFTTWE-- 165 Query: 308 LSGVDIQI 315 + D+ I Sbjct: 166 TNNGDVSI 173 >3ZVH-B nrPDB Length = 438 Score = 31.0 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 27/146 (18%), Positives = 53/146 (36%), Gaps = 12/146 (8%) Query: 257 YDLDFKSPDDPARHISGEKLGELYKSFIKNY-PV-VSIEDPFDQDD----WATWTSFL-- 308 + +D A + + + + ++ + P + IE P D +D Sbjct: 235 FHIDVYGTIGAAFDVDIKAMADYIQTLAEAAKPFHLRIEGPMDVEDRQKQMEAMRDLRAE 294 Query: 309 ---SGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGW 365 GVD ++V D+ T + + + KA + + +K +G V A ++NG Sbjct: 295 LDGRGVDAELVADEWCNT-VEDVKFFTDNKAGHMVQIKTPDLGGVNNIADAIMYCKANGM 353 Query: 366 GVMVSHRSGETEDTFIADLVVGLCTG 391 G ET + +G+ G Sbjct: 354 GAYCGGTCNETNRSAEVTTNIGMACG 379 >5OLC-A nrPDB Length = 396 Score = 30.6 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 31/81 (38%), Gaps = 9/81 (11%) Query: 285 KNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKA-CNCLLLK 343 + + + E+P +D+ + I I G + + + ++ +C+ + Sbjct: 220 EKFDISWFEEPVSPEDYDGYKRLRQNTTIPISGGEC-----EYLKYGFKRLFDKDCVDIA 274 Query: 344 VNQI---GSVTESIQACKLAQ 361 I G +TE + LAQ Sbjct: 275 QPDICAAGGLTEVKKIATLAQ 295 >3T8Q-A nrPDB Length = 370 Score = 30.6 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 17/101 (16%), Positives = 42/101 (41%), Gaps = 6/101 (5%) Query: 266 DPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVG--DDLTVT 323 D E+ E+ ++ + E+P ++ + + I + G D + Sbjct: 185 DANSCYGPEQAIEV-GKMLEQNGISHYEEPCPYWEYEQTQQVTNALSIDVTGGEQDCELQ 243 Query: 324 NPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNG 364 N +R+ +E KA + + + +G +T +++ ++A G Sbjct: 244 NWRRM---IEMKAVDIVQPDICYLGGITRTLRVAEMAHKAG 281 >3ES8-A nrPDB Length = 391 Score = 30.2 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 38/96 (39%), Gaps = 7/96 (7%) Query: 292 IEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVT 351 IE P ++D+ D I V + K+ + ++K A + + IG +T Sbjct: 220 IESPAPRNDFDGLYQLRLKTDYPI---SEHVWSFKQQQEMIKKDAIDIFNISPVFIGGLT 276 Query: 352 ESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVG 387 + +A A+ V++ G T++ + + Sbjct: 277 SAKKAAYAAEVASKDVVL----GTTQELSVGTAAMA 308 >4GFI-A nrPDB Length = 329 Score = 29.8 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 43/94 (45%), Gaps = 7/94 (7%) Query: 277 GELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQ-IVGDDLTVTNPKRIAQAVEKK 335 E Y + IE P A + L+ ++ ++ D +V + + +A + + Sbjct: 187 IEYYLKLAAELKISLIEQPLP----AGKDAMLARIEHPVLICADESVHSTEDLA-GLRDR 241 Query: 336 ACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMV 369 + + +K+++ G +TE++ A+ G+ +MV Sbjct: 242 Y-DAINIKLDKTGGLTEALVMKAEAERLGFTIMV 274 >6ILH-A nrPDB Length = 521 Score = 29.8 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 15/52 (28%), Positives = 21/52 (40%), Gaps = 19/52 (36%) Query: 147 VPAFNVINGGSHAG------NKLAMQEFMILPVGASSFKEAMRIGAEVYHHL 192 P N+I GG+ A N+L M +M RI E+YH + Sbjct: 200 TPMMNIIPGGAVAKPFITYHNELDMNLYM-------------RIAPELYHKM 238 >1JPD-X nrPDB Length = 324 Score = 29.8 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 21/104 (20%), Positives = 41/104 (39%), Gaps = 6/104 (5%) Query: 266 DPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNP 325 D E L + + V +E P D A +F+ + I D+ T Sbjct: 179 DANESWRAEGLAAR-CQLLADLGVAMLEQPLPAQDDAALENFIHPL--PICADESCHTRS 235 Query: 326 KRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMV 369 A K + +K+++ G +TE++ A++ G+ +M+ Sbjct: 236 NLKAL---KGRYEMVNIKLDKTGGLTEALALATEARAQGFSLML 276 >6CHD-A nrPDB Length = 597 Score = 29.5 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 15/52 (28%), Positives = 21/52 (40%), Gaps = 19/52 (36%) Query: 147 VPAFNVINGGSHAG------NKLAMQEFMILPVGASSFKEAMRIGAEVYHHL 192 P N+I GG+ A N+L M +M RI E+YH + Sbjct: 268 TPMMNIIPGGAVAKPFITYHNELDMNLYM-------------RIAPELYHKM 306 >5HQA-A nrPDB Length = 669 Score = 29.5 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 19/97 (19%), Positives = 34/97 (35%) Query: 253 RNGKYDLDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVD 312 +N KY +DF + + + N V S P+D D A T + Sbjct: 291 KNTKYYMDFAAKYGFDGVLVEGWNTGWDGDWFFNGDVFSFTQPYDDFDIAALTKYSKQTG 350 Query: 313 IQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGS 349 +Q++G T N + + V+Q+ + Sbjct: 351 VQLIGHHETSGNVSNYRKQMADAFALYEKSNVSQVKT 387 >4WMZ-A nrPDB Length = 539 Score = 29.5 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 27/122 (22%), Positives = 50/122 (40%), Gaps = 8/122 (6%) Query: 80 KKLSVVDQEKVDKFMIEL---DGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIAD 136 K + D++ +D M DG + + AN ++GV + AA L H+A+ Sbjct: 274 KNNDIQDRDLIDSLMKNSTYKDGVKMTDQEIANLLIGVLMGGQHTSAATSAWILL-HLAE 332 Query: 137 LAGNPDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVI 196 L V++GG +QE +P+ + KE +R+ ++ + V+ Sbjct: 333 RPDVQQE-LYEEQMRVLDGGKKELTYDLLQE---MPLLNQTIKETLRMHHPLHSLFRKVM 388 Query: 197 KA 198 K Sbjct: 389 KD 390 >6MRP-B nrPDB Length = 220 Score = 29.1 bits (64), Expect = 3.5, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 33/81 (40%), Gaps = 8/81 (9%) Query: 214 APNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSPDDPARHISG 273 AP + + E ++LLK I++ P + + + F++ S ++ Sbjct: 111 APEVQSSEEYIQLLKKLIESPSIPHQYWLTLQYLLKHFFK--------LSQTSSKNLLNA 162 Query: 274 EKLGELYKSFIKNYPVVSIED 294 L EL+ + +P S E+ Sbjct: 163 RVLSELFSPLLFRFPAASSEN 183 >5KR3-A nrPDB Length = 479 Score = 29.1 bits (64), Expect = 3.6, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 30/72 (41%), Gaps = 3/72 (4%) Query: 163 LAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNE 222 LA EFM + F A+++G +V ++ A GD GFAP ++ Sbjct: 402 LAALEFMADKDARTPFDPALKVGPKVS---AAALEDGMIARAMPHGDILGFAPPLVTTRA 458 Query: 223 ALELLKTAIQAA 234 ++ + + A Sbjct: 459 EVDEIVGIAKQA 470 >4A35-A nrPDB Length = 441 Score = 29.1 bits (64), Expect = 4.2, Method: Composition-based stats. Identities = 20/102 (19%), Positives = 38/102 (37%), Gaps = 7/102 (6%) Query: 266 DPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVT-- 323 D + + E K P+ IE+P DD + + + + G + Sbjct: 251 DANQRWDVPEAVEWMSKLAKFKPLW-IEEPTSPDDILGHATISKAL-VPL-GIGIATGEQ 307 Query: 324 --NPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSN 363 N Q ++ KA L + ++GSV E++ +A+ Sbjct: 308 CHNRVIFKQLLQAKALQFLQIDSCRLGSVNENLSVLLMAKKF 349 >5XD7-A nrPDB Length = 368 Score = 29.1 bits (64), Expect = 4.4, Method: Composition-based stats. Identities = 10/50 (20%), Positives = 22/50 (44%), Gaps = 1/50 (2%) Query: 266 DPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQI 315 D ++ E+ +L K+ ++ Y + E+P DD+ + I + Sbjct: 198 DANYSLTVEQAIKLSKA-VEQYDITWFEEPTLPDDYKGFAEIADNTAIPL 246 >3DDM-A nrPDB Length = 392 Score = 28.7 bits (63), Expect = 4.6, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 15/31 (48%) Query: 108 ANAILGVSLAVCKAGAAEKGVPLYRHIADLA 138 A AI G+ +A+C A G PL+ + Sbjct: 114 AQAIAGLDIALCDLAARRAGQPLWAWLGGSG 144 >1KKR-A nrPDB Length = 413 Score = 28.7 bits (63), Expect = 5.5, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 30/81 (37%), Gaps = 1/81 (1%) Query: 310 GVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMV 369 G ++IV D+ T + + +C+ + +K +G + + A +G Sbjct: 299 GSGVKIVADEWCNTYQDIV-DFTDAGSCHMVQIKTPDLGGIHNIVDAVLYCNKHGMEAYQ 357 Query: 370 SHRSGETEDTFIADLVVGLCT 390 ETE + + V L Sbjct: 358 GGTCNETEISARTCVHVALAA 378 >2JI6-A nrPDB Length = 568 Score = 28.7 bits (63), Expect = 5.8, Method: Composition-based stats. Identities = 30/136 (22%), Positives = 54/136 (39%), Gaps = 20/136 (14%) Query: 51 DGDKSRYLGK-------GVLKAVEHINKTLGPALLEKKLSVVDQ--EKVDKFMIELDGTE 101 DG+K++ GK G++ + L +S+V++ +D + +D + Sbjct: 356 DGNKAKLAGKMTAETPSGMMNYSNSLGVVRDFMLANPDISLVNEGANALDNTRMIVDMLK 415 Query: 102 NKSKF--GANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPD---------LVLPVPAF 150 + + G ++G+ + C A AA G P+ D A LPV Sbjct: 416 PRKRLDSGTWGVMGIGMGYCVAAAAVTGKPVIAVEGDSAFGFSGMELETICRYNLPVTVI 475 Query: 151 NVINGGSHAGNKLAMQ 166 + NGG + GN+ Q Sbjct: 476 IMNNGGIYKGNEADPQ 491 >5XY3-B nrPDB Length = 415 Score = 28.3 bits (62), Expect = 7.4, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 26/66 (39%), Gaps = 14/66 (21%) Query: 312 DIQIVGDDLTVTNPKRIAQAVEKKACNCLL---LKVNQIGSVTESIQACKLAQSNGWGVM 368 +IQI G D+ + +L +KV + + E I + + GW + Sbjct: 198 EIQINGGDVAA----------KLNYAKSILEKEIKVADVFTEGEQIDTIGVGKGFGWEGV 247 Query: 369 VSHRSG 374 + HR G Sbjct: 248 I-HRYG 252 >4GLW-A nrPDB Length = 305 Score = 27.9 bits (61), Expect = 7.8, Method: Composition-based stats. Identities = 9/46 (19%), Positives = 22/46 (47%) Query: 259 LDFKSPDDPARHISGEKLGELYKSFIKNYPVVSIEDPFDQDDWATW 304 + D H G K+ + ++ + YP+ S++D F +++ + Sbjct: 46 YPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAF 91 >4M0X-A nrPDB Length = 371 Score = 27.9 bits (61), Expect = 8.0, Method: Composition-based stats. Identities = 28/157 (17%), Positives = 60/157 (38%), Gaps = 11/157 (7%) Query: 219 ENNEALELLKTAIQA--AGYPD-KVVIGMDVAASEFYRNGKYDLDFKSPDDPARHIS--- 272 A +L+ A Q G+ K +G + A ++ D+ PD+ A + Sbjct: 142 SAGSASDLIDEAAQKLDVGHRSFKFKMGAEPADTD--SRRVLDVLECIPDECAVIVDPNG 199 Query: 273 --GEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQ 330 E + + + V E P + + + I I+ D+ T + IA Sbjct: 200 RWSELEAHRWLPILADAGVTVAEQPIARWNTDGLARLRDKLSIPIMADESVTTVQQAIAL 259 Query: 331 AVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGV 367 A + A + +K+ + G ++ + + +A+++G Sbjct: 260 A-DAGAVSAFAIKIPKSGGLSRAREIAAIAEASGLAC 295 >6D81-A nrPDB Length = 193 Score = 27.9 bits (61), Expect = 9.2, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 33/81 (40%), Gaps = 8/81 (9%) Query: 214 APNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSPDDPARHISG 273 AP + + E ++LLK I++ P + + + F++ S ++ Sbjct: 101 APEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLLKHFFK--------LSQTSSKNLLNA 152 Query: 274 EKLGELYKSFIKNYPVVSIED 294 L EL+ + +P S E+ Sbjct: 153 RVLSELFSPLLFRFPAASSEN 173 >5KR5-A nrPDB Length = 479 Score = 27.9 bits (61), Expect = 9.9, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 31/76 (40%), Gaps = 4/76 (5%) Query: 163 LAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNE 222 LA EFM + F A+++ +V ++ A GD GFAP ++ Sbjct: 402 LAALEFMADKGARTPFDPALKVSQKV---AAAALEDGLIVRALPHGDILGFAPPLVTTRA 458 Query: 223 ALELLKTAIQAAGYPD 238 ++ + AI + + Sbjct: 459 EVDEIV-AIAKEAFDE 473 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.315 0.153 0.463 Lambda K H 0.267 0.0466 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,795,555 Number of Sequences: 36641 Number of extensions: 1009929 Number of successful extensions: 2980 Number of sequences better than 10.0: 105 Number of HSP's better than 10.0 without gapping: 78 Number of HSP's successfully gapped in prelim test: 79 Number of HSP's that attempted gapping in prelim test: 2607 Number of HSP's gapped (non-prelim): 175 length of query: 434 length of database: 10,336,785 effective HSP length: 100 effective length of query: 334 effective length of database: 6,672,685 effective search space: 2228676790 effective search space used: 2228676790 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 61 (27.9 bits)