BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P15428 (266 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2GDZ-A nrPDB 520 e-148 5ILO-A nrPDB 139 9e-34 1K2W-A nrPDB 120 4e-28 1X1T-A nrPDB 118 3e-27 4CQM-B nrPDB 112 2e-25 4E6P-A nrPDB 111 3e-25 3RSH-A nrPDB 110 5e-25 3W8F-A nrPDB 110 7e-25 4DMM-A nrPDB 108 3e-24 2HQ1-A nrPDB 106 1e-23 1HXH-A nrPDB 105 2e-23 3OSU-A nrPDB 104 4e-23 5YSS-A nrPDB 103 5e-23 5ITV-A nrPDB 102 2e-22 1Q7C-A nrPDB 102 2e-22 4JRO-A nrPDB 101 3e-22 2UVD-A nrPDB 101 3e-22 4M8S-A nrPDB 101 3e-22 2Q2Q-A nrPDB 101 4e-22 4RZH-A nrPDB 100 5e-22 2EW8-A nrPDB 100 7e-22 2PNF-A nrPDB 99 2e-21 3EMK-A nrPDB 99 3e-21 5CDY-A nrPDB 99 3e-21 4NBV-A nrPDB 98 3e-21 4NBT-A nrPDB 97 5e-21 2CFC-A nrPDB 97 7e-21 3UVE-A nrPDB 97 8e-21 3V2H-A nrPDB 97 8e-21 3WOH-A nrPDB 95 3e-20 3WTC-A nrPDB 95 4e-20 2C07-A nrPDB 94 5e-20 1GEG-A nrPDB 93 1e-19 1NFF-A nrPDB 92 3e-19 3RWB-A nrPDB 92 3e-19 3LYL-A nrPDB 91 5e-19 3OEC-A nrPDB 91 6e-19 2NM0-A nrPDB 90 1e-18 2CDH-G nrPDB 88 3e-18 2O23-A nrPDB 88 4e-18 1B15-A nrPDB 87 8e-18 5EJ2-A nrPDB 87 1e-17 3FTP-A nrPDB 87 1e-17 4DBZ-A nrPDB 86 1e-17 3AUT-A nrPDB 86 2e-17 3V2G-A nrPDB 86 2e-17 4CQL-A nrPDB 86 2e-17 4TRR-A nrPDB 86 2e-17 5OVJ-A nrPDB 86 2e-17 5OVL-A nrPDB 85 3e-17 3F9I-A nrPDB 84 7e-17 4IIN-A nrPDB 84 8e-17 4Z9Y-A nrPDB 83 1e-16 4BO1-A nrPDB 83 1e-16 3GRP-A nrPDB 83 1e-16 2PH3-A nrPDB 83 1e-16 4IS3-A nrPDB 83 1e-16 4AVY-A nrPDB 82 2e-16 1E3W-A nrPDB 82 3e-16 3VZS-A nrPDB 82 3e-16 5OJG-A nrPDB 81 4e-16 3V8B-A nrPDB 80 6e-16 5JS6-A nrPDB 80 9e-16 3WYE-A nrPDB 80 1e-15 4RGB-A nrPDB 80 1e-15 3T7C-A nrPDB 80 1e-15 1UZM-A nrPDB 79 1e-15 1YXM-A nrPDB 79 1e-15 4MOW-A nrPDB 79 2e-15 5B1Y-A nrPDB 79 2e-15 3RKU-A nrPDB 79 3e-15 4K6F-A nrPDB 78 3e-15 4KMS-A nrPDB 78 4e-15 3O4R-A nrPDB 77 7e-15 3EZL-A nrPDB 77 8e-15 1GEE-A nrPDB 76 2e-14 2HSD-A nrPDB 75 2e-14 4HP8-A nrPDB 74 5e-14 3ZV3-A nrPDB 74 5e-14 2B4Q-A nrPDB 74 6e-14 2FWM-X nrPDB 74 7e-14 1MG5-A nrPDB 73 1e-13 1AE1-A nrPDB 73 1e-13 3UF0-A nrPDB 73 1e-13 1BDB-A nrPDB 72 2e-13 5VT6-A nrPDB 72 2e-13 3A28-C nrPDB 72 3e-13 4RZI-B nrPDB 72 3e-13 2AG5-A nrPDB 72 3e-13 2AE2-A nrPDB 72 3e-13 5U9P-A nrPDB 71 4e-13 3OIC-A nrPDB 71 5e-13 3OML-A nrPDB 71 5e-13 2ZAT-A nrPDB 71 5e-13 3U5T-A nrPDB 71 6e-13 4IIV-A nrPDB 69 2e-12 5T5Q-A nrPDB 69 3e-12 4EGF-A nrPDB 69 3e-12 1AHH-A nrPDB 68 4e-12 3R3S-A nrPDB 68 5e-12 4GKB-A nrPDB 67 7e-12 6CI9-A nrPDB 67 7e-12 4CR6-A nrPDB 67 9e-12 3UN1-A nrPDB 66 1e-11 4DA9-A nrPDB 66 2e-11 4DRY-A nrPDB 65 4e-11 6NRP-A nrPDB 64 5e-11 2X9N-A nrPDB 64 7e-11 1DOH-A nrPDB 63 1e-10 5JY1-A nrPDB 62 2e-10 3PXX-A nrPDB 62 3e-10 5O3Z-A nrPDB 62 3e-10 3PPI-A nrPDB 61 4e-10 4HBG-A nrPDB 61 5e-10 3D3W-A nrPDB 60 1e-09 5IZ4-A nrPDB 59 2e-09 1A27-A nrPDB 59 3e-09 6CGE-A nrPDB 59 3e-09 3GDF-A nrPDB 57 8e-09 1H5Q-A nrPDB 57 9e-09 1CYD-A nrPDB 56 2e-08 2BGM-A nrPDB 54 6e-08 2NWQ-A nrPDB 54 1e-07 3KZV-A nrPDB 53 1e-07 1O5I-A nrPDB 52 3e-07 1P33-A nrPDB 52 3e-07 2BFA-A nrPDB 52 4e-07 2QHX-A nrPDB 51 4e-07 5LCX-A nrPDB 51 6e-07 3U4C-A nrPDB 49 3e-06 5L51-A nrPDB 49 3e-06 4NR0-A nrPDB 46 1e-05 5PGZ-A nrPDB 46 2e-05 3O26-A nrPDB 45 3e-05 2HRB-A nrPDB 44 7e-05 2YW9-A nrPDB 44 8e-05 1N5D-A nrPDB 44 9e-05 3E9N-A nrPDB 44 9e-05 4FC7-A nrPDB 43 1e-04 1OAA-A nrPDB 43 1e-04 3BHI-A nrPDB 42 2e-04 5WQO-A nrPDB 42 2e-04 2P91-A nrPDB 42 3e-04 4Z3K-A nrPDB 41 5e-04 4HWK-A nrPDB 41 5e-04 3DWF-A nrPDB 40 8e-04 3U9L-A nrPDB 39 0.002 5KOI-A nrPDB 39 0.002 5TF4-A nrPDB 39 0.003 1W73-A nrPDB 39 0.003 3GRK-A nrPDB 38 0.004 3K2E-A nrPDB 37 0.012 5YCX-A nrPDB 36 0.016 2HUN-A nrPDB 35 0.037 5I9N-A nrPDB 34 0.063 5CFZ-A nrPDB 34 0.066 2O2S-A nrPDB 34 0.073 4JQC-A nrPDB 34 0.082 2DKN-A nrPDB 31 0.57 4R86-A nrPDB 30 0.73 1FJH-A nrPDB 30 1.2 5Y7Y-B nrPDB 30 1.2 5Z57-V nrPDB 30 1.4 3RFT-A nrPDB 29 2.1 4C9B-B nrPDB 28 3.1 3OIG-A nrPDB 28 3.4 6E3T-A nrPDB 28 4.2 6DVV-A nrPDB 28 5.0 4J3F-A nrPDB 28 5.3 4GBU-A nrPDB 28 5.3 3UCF-A nrPDB 28 5.4 4RNU-A nrPDB 28 5.7 3D02-A nrPDB 27 6.9 5FAU-A nrPDB 27 7.3 4LIS-A nrPDB 27 8.4 4G7A-A nrPDB 27 9.4 >2GDZ-A nrPDB Length = 267 Score = 520 bits (1339), Expect = e-148, Method: Compositional matrix adjust. Identities = 253/256 (98%), Positives = 254/256 (99%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAAL EQFEPQKTLFIQ Sbjct: 5 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLFIQ 64 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYM 122 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYM Sbjct: 65 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYM 124 Query: 123 SKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAIC 182 SKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAIC Sbjct: 125 SKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAIC 184 Query: 183 PGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNGAI 242 PGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNGAI Sbjct: 185 PGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNGAI 244 Query: 243 MKITTSKGIHFQDYDT 258 MKITTSKGIHFQDY + Sbjct: 245 MKITTSKGIHFQDYGS 260 >5ILO-A nrPDB Length = 271 Score = 139 bits (351), Expect = 9e-34, Method: Compositional matrix adjust. Identities = 79/183 (43%), Positives = 115/183 (62%), Gaps = 7/183 (3%) Query: 5 GKVALVTGAAQGIGRAFAEALLLKGA-KVALVDW--NLEAGVQCKAALDEQFEPQKTLFI 61 GK A+VTG A GIG ++ LL GA KVA++D NLE V+ +AA Q + I Sbjct: 15 GKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAA----HPTQSVMII 70 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDY 121 + DVA+++ + T+ ++ FG +DI+VN AG+ N+K+ ++TL +NL +I+ T L Y Sbjct: 71 KMDVANKKGVEATYEEIAKTFGNIDIVVNVAGIFNDKDVQRTLLVNLGGIINSTLSALPY 130 Query: 122 MSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAI 181 M K NGG+GGI++NMSS+ GL P+ PVY A+K GI+ FTR A SG++ + Sbjct: 131 MGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRSGIKFVTV 190 Query: 182 CPG 184 CPG Sbjct: 191 CPG 193 >1K2W-A nrPDB Length = 256 Score = 120 bits (302), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 77/197 (39%), Positives = 114/197 (57%), Gaps = 21/197 (10%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M ++GK AL+TG+A+GIGRAFAEA + +GA+VA+ D NLEA A + P Sbjct: 1 MRLDGKTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAA----EIGPAACA- 55 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVI 112 I DV DQ + +++D +G +DILVNNA + + +++++ IN + Sbjct: 56 IALDVTDQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAIN----V 111 Query: 113 SGTYLGLDYMSKQ--NGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAAN 170 SGT + +++ GG GG IINM+S AG A VYCA+K ++ T+SA L N Sbjct: 112 SGTLFMMQAVARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGL--N 169 Query: 171 LMNSGVRLNAICPGFVN 187 L+ G+ +NAI PG V+ Sbjct: 170 LIRHGINVNAIAPGVVD 186 >1X1T-A nrPDB Length = 260 Score = 118 bits (295), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 75/199 (37%), Positives = 108/199 (54%), Gaps = 15/199 (7%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQ-CKAALDEQFEPQKTLFI 61 + GKVA+VTG+ GIG A AL +GA + L + A ++ +A L Q K L+ Sbjct: 2 LKGKVAVVTGSTSGIGLGIATALAAQGADIVLNGFGDAAEIEKVRAGLAAQ-HGVKVLYD 60 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVIS 113 D++ + +R V GR+DILVNNAG+ + + W+ L +NL +V Sbjct: 61 GADLSKGEAVRGLVDNAVRQMGRIDILVNNAGIQHTALIEDFPTEKWDAILALNLSAVFH 120 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 GT L +M KQ G IIN++S GL+ A + Y A+KHG+VGFT+ AL Sbjct: 121 GTAAALPHMKKQGFGR---IINIASAHGLVASANKSAYVAAKHGVVGFTKVTAL--ETAG 175 Query: 174 SGVRLNAICPGFVNTAILE 192 G+ NAICPG+V T ++E Sbjct: 176 QGITANAICPGWVRTPLVE 194 >4CQM-B nrPDB Length = 244 Score = 112 bits (279), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 78/248 (31%), Positives = 130/248 (52%), Gaps = 29/248 (11%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 KV V G ++GIGRA A+ + KG ++A++ NLE KAA + L CDV Sbjct: 10 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEG---AKAAAGDLGGDH--LAFSCDV 64 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLG------- 118 A + +++TF ++ H GR++ LVN AG+N + +T ++VS + LG Sbjct: 65 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 124 Query: 119 -LDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 + M +Q GG I+N+ S+ GL + Q VY ASK G+VGF+R ALA + +R Sbjct: 125 AMRTMIQQQGGS---IVNVGSIVGLKGNSGQSVYSASKGGLVGFSR--ALAKEVARKKIR 179 Query: 178 LNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDA 237 +N + PGFV+T + + +++E H+K I + +A+ ++ L+E Sbjct: 180 VNVVAPGFVHTDMTKDLKEE-----------HLKKNIPLGRFGETIEVAHAVVFLLESPY 228 Query: 238 LNGAIMKI 245 + G ++ + Sbjct: 229 ITGHVLVV 236 >4E6P-A nrPDB Length = 259 Score = 111 bits (277), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 74/196 (37%), Positives = 107/196 (54%), Gaps = 21/196 (10%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 + GK AL+TG+A+GIGRAFAEA + +GA VA+ D ++E Q A + P + Sbjct: 5 RLEGKSALITGSARGIGRAFAEAYVREGATVAIADIDIERARQAAA----EIGP-AAYAV 59 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVIS 113 Q DV Q + V+H G LDILVNNA + + +++EK IN ++ Sbjct: 60 QMDVTRQDSIDAAIAATVEHAGGLDILVNNAALFDLAPIVEITRESYEKLFAIN----VA 115 Query: 114 GTYLGLDYMSKQ--NGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANL 171 GT L ++Q G GG IINM+S AG A +YCA+K ++ T+SA L +L Sbjct: 116 GTLFTLQAAARQMIAQGRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAGL--DL 173 Query: 172 MNSGVRLNAICPGFVN 187 + + +NAI PG V+ Sbjct: 174 IKHRINVNAIAPGVVD 189 >3RSH-A nrPDB Length = 251 Score = 110 bits (276), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 73/206 (35%), Positives = 115/206 (55%), Gaps = 18/206 (8%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M++ GKVALVTGA++GIG+A AE L +GAKV + E+G Q A D + K + Sbjct: 8 MNLEGKVALVTGASRGIGKAIAELLAERGAKV-IGTATSESGAQ--AISDYLGDNGKGMA 64 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVI 112 + +V + + + + + D FG +DILVNNAG+ E+ W ++ NL S+ Sbjct: 65 L--NVTNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIF 122 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + L M K+ G IIN+ S+ G M A Q Y A+K G++GFT+S +A + Sbjct: 123 RLSKAVLRGMMKKRQGR---IINVGSVVGTMGNAGQANYAAAKAGVIGFTKS--MAREVA 177 Query: 173 NSGVRLNAICPGFVNTAILESIEKEE 198 + GV +N + PGF+ T + +++ E+ Sbjct: 178 SRGVTVNTVAPGFIETDMTKALNDEQ 203 >3W8F-A nrPDB Length = 260 Score = 110 bits (275), Expect = 7e-25, Method: Compositional matrix adjust. Identities = 70/198 (35%), Positives = 100/198 (50%), Gaps = 13/198 (6%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 + GK A+VTG+ GIG A A L GA V + + ++ + + E K ++ Sbjct: 2 LKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVKAYYLN 61 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEK--------NWEKTLQINLVSVISG 114 D++D Q RD K + G LDILVNNAG+ + W + +NL +V G Sbjct: 62 ADLSDAQATRDFIAKAAEALGGLDILVNNAGIQHTAPIEEFPVDKWNAIIALNLSAVFHG 121 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 T L M KQ G IIN++S GL+ + Y A+KHG+VG T+ AL Sbjct: 122 TAAALPIMQKQGWGR---IINIASAHGLVASVNKSAYVAAKHGVVGLTKVTAL--ENAGK 176 Query: 175 GVRLNAICPGFVNTAILE 192 G+ NAICPG+V T ++E Sbjct: 177 GITCNAICPGWVRTPLVE 194 >4DMM-A nrPDB Length = 269 Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 72/230 (31%), Positives = 121/230 (52%), Gaps = 21/230 (9%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 ++ALVTGA++GIGRA A L GAKVA V++ AG + + ++ DV Sbjct: 29 RIALVTGASRGIGRAIALELAAAGAKVA-VNYASSAGAADEVVAAIAAAGGEAFAVKADV 87 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEK--------NWEKTLQINLVSVISGTYL 117 + + ++ F V++ +GRLD+LVNNAG+ + +W+ L +NL V + Sbjct: 88 SQESEVEALFAAVIERWGRLDVLVNNAGITRDTLLLRMKRDDWQSVLDLNLGGVFLCSRA 147 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 M KQ G IIN++S+ G M Q Y A+K G++G T++ +A L + G+ Sbjct: 148 AAKIMLKQRSGR---IINIASVVGEMGNPGQANYSAAKAGVIGLTKT--VAKELASRGIT 202 Query: 178 LNAICPGFVNTAILESIEKEE-----NMGQYIEYKDHIKDMIKYYGILDP 222 +NA+ PGF+ T + + E+ +G+Y E + + ++++ DP Sbjct: 203 VNAVAPGFIATDMTSELAAEKLLEVIPLGRYGEAAE-VAGVVRFLAA-DP 250 >2HQ1-A nrPDB Length = 247 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 82/256 (32%), Positives = 125/256 (48%), Gaps = 44/256 (17%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M + GK A+VTG+++G+G+A A L GA + L G +LD E K Sbjct: 1 MQLKGKTAIVTGSSRGLGKAIAWKLGNMGANIVL------NGSPASTSLDATAEEFKAAG 54 Query: 61 IQC-----DVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQIN 107 I DV + + + + + +D FGR+DILVNNAG+ +EK+W+ L N Sbjct: 55 INVVVAKGDVKNPEDVENMVKTAMDAFGRIDILVNNAGITRDTLMLKMSEKDWDDVLNTN 114 Query: 108 LVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 L S T M KQ G+ IIN++S+AG++ A Q Y ASK G++GFT+S + Sbjct: 115 LKSAYLCTKAVSKIMLKQKSGK---IINITSIAGIIGNAGQANYAASKAGLIGFTKS--I 169 Query: 168 AANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDM------IKYYGILD 221 A G+ NA+ PG + T + + + D +K+M +K +G Sbjct: 170 AKEFAAKGIYCNAVAPGIIKTDMTDVLP------------DKVKEMYLNNIPLKRFGT-- 215 Query: 222 PPLIANGLITLIEDDA 237 P +AN + L DD+ Sbjct: 216 PEEVANVVGFLASDDS 231 >1HXH-A nrPDB Length = 253 Score = 105 bits (262), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 69/200 (34%), Positives = 106/200 (53%), Gaps = 17/200 (8%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 + GKVALVTG A G+G + LL +GAKVA D N AG Q A L E +++F+ Sbjct: 3 RLQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGE-----RSMFV 57 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVIS 113 + DV+ + V G L++LVNNAG+ +++ + L+IN SV Sbjct: 58 RHDVSSEADWTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRLEDFSRLLKINTESVFI 117 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 G G+ M + GG IINM+S++ +P+ Q Y ASK + TR+AAL+ Sbjct: 118 GCQQGIAAMKET----GGSIINMASVSSWLPIEQYAGYSASKAAVSALTRAAALSCRKQG 173 Query: 174 SGVRLNAICPGFVNTAILES 193 +R+N+I P + T ++++ Sbjct: 174 YAIRVNSIHPDGIYTPMMQA 193 >3OSU-A nrPDB Length = 246 Score = 104 bits (260), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 72/203 (35%), Positives = 114/203 (56%), Gaps = 20/203 (9%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKA-ALDEQFEPQ--KTLFIQ 62 K ALVTGA++GIGR+ A L +G VA V++ AG + KA A+ E+ + + + IQ Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVA-VNY---AGSKEKAEAVVEEIKAKGVDSFAIQ 60 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVISG 114 +VAD +++ ++VV FG LD+LVNNAG+ E+ W+ + NL V + Sbjct: 61 ANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNC 120 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 M +Q G IIN+SS+ G + Q Y A+K G++G T+SA A L + Sbjct: 121 IQKATPQMLRQ---RSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSA--ARELASR 175 Query: 175 GVRLNAICPGFVNTAILESIEKE 197 G+ +NA+ PGF+ + + +++ E Sbjct: 176 GITVNAVAPGFIVSDMTDALSDE 198 >5YSS-A nrPDB Length = 256 Score = 103 bits (258), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 70/201 (34%), Positives = 105/201 (52%), Gaps = 19/201 (9%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTL- 59 M++ GK ALVTG+ GIG A+ L GA + L + AA D + KT Sbjct: 1 MNLTGKTALVTGSTSGIGLGIAQVLAQAGATLILNGFG-----DVDAAKDAVAQYGKTPG 55 Query: 60 FIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEK--------NWEKTLQINLVSV 111 + D++D+ Q+ D R FG +DIL+NNAG+ + W + INL SV Sbjct: 56 YHGADLSDEAQIADMMRYAESEFGGVDILINNAGIQHVSPIETFPVDKWNAIIAINLSSV 115 Query: 112 ISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANL 171 T L L M +N G IIN++S+ GL+ ++ Y A+KHG+VG T++ AL Sbjct: 116 FHTTRLALPGMRARNWGR---IINIASVHGLVASKEKSAYVAAKHGVVGLTKTIAL--ET 170 Query: 172 MNSGVRLNAICPGFVNTAILE 192 + + NA+CPG+V T +++ Sbjct: 171 AQTEITCNALCPGWVLTPLVQ 191 >5ITV-A nrPDB Length = 255 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 73/243 (30%), Positives = 112/243 (46%), Gaps = 17/243 (6%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M++ K L+TG A GIG A +A L + A V + D + G A+ + + F Sbjct: 3 MNLTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQG----EAMVRKENNDRLHF 58 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVI 112 +Q D+ D+ + V FG LD+L+NNAG+ +W K LQ+NL + Sbjct: 59 VQTDITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMF 118 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + L +M G IIN S+ GL+ P Y ASK G++ T+S +A + Sbjct: 119 LMSKHALKHMLAAGKGN---IINTCSVGGLVAWPDIPAYNASKGGVLQLTKS--MAVDYA 173 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 +R+N +CPG ++T + E E N G E K + + P IAN ++ L Sbjct: 174 KHQIRVNCVCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRLGKPEEIANVMLFL 233 Query: 233 IED 235 D Sbjct: 234 ASD 236 >1Q7C-A nrPDB Length = 244 Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 70/209 (33%), Positives = 108/209 (51%), Gaps = 18/209 (8%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M+ GK+ALVTGA++GIGRA AE L +GAKV + E G Q A D K L Sbjct: 1 MNFEGKIALVTGASRGIGRAIAETLAARGAKV-IGTATSENGAQ--AISDYLGANGKGLM 57 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVI 112 + +V D + K+ FG +DILVNNAG+ ++ W ++ NL SV Sbjct: 58 L--NVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVF 115 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + + M K+ G II + S+ G M Q + A+K G++GF++S LA + Sbjct: 116 RLSKAVMRAMMKKRHGR---IITIGSVVGTMGNGGQANFAAAKAGLIGFSKS--LAREVA 170 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMG 201 + G+ +N + PGF+ T + ++ ++ G Sbjct: 171 SRGITVNVVAPGFIETDMTRALSDDQRAG 199 >4JRO-A nrPDB Length = 271 Score = 101 bits (252), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 69/207 (33%), Positives = 111/207 (53%), Gaps = 18/207 (8%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWN--LEAGVQCKAALDEQFEPQKT 58 M + GKVA+VTG ++GIGR A L +GA + ++N EA + + E + Sbjct: 25 MTLQGKVAVVTGGSRGIGRDIAINLAKEGANI-FFNYNGSPEAAEETAKLVAEHGVEVEA 83 Query: 59 LFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVS 110 + + +VA + + F++ ++ FGR+DILVNNAG+ E W+ + INL Sbjct: 84 M--KANVAIAEDVDAFFKQAIERFGRVDILVNNAGITRDNLLMRMKEDEWDDVININLKG 141 Query: 111 VISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAAN 170 T M KQ G+ IINM+S+ GL+ A Q Y ASK G++G T++ A Sbjct: 142 TFLCTKAVSRTMMKQRAGK---IINMASVVGLIGNAGQANYVASKAGVIGLTKTT--ARE 196 Query: 171 LMNSGVRLNAICPGFVNTAILESIEKE 197 L G+ +NA+ PGF+ T + + ++++ Sbjct: 197 LAPRGINVNAVAPGFITTDMTDKLDEK 223 >2UVD-A nrPDB Length = 246 Score = 101 bits (252), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 71/203 (34%), Positives = 116/203 (57%), Gaps = 20/203 (9%) Query: 5 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKA--ALDE-QFEPQKTLFI 61 GKVALVTGA++GIGRA A L +GA V +V++ AG + KA +DE + + + Sbjct: 4 GKVALVTGASRGIGRAIAIDLAKQGANV-VVNY---AGNEQKANEVVDEIKKLGSDAIAV 59 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVIS 113 + DVA+ + + + ++ VD FG++DILVNNAGV E+ W+ + NL V Sbjct: 60 RADVANAEDVTNMVKQTVDVFGQVDILVNNAGVTKDNLLMRMKEEEWDTVINTNLKGVFL 119 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 T +M +Q G I+N++S+ G+ Q Y A+K G++G T+++ A L + Sbjct: 120 CTKAVSRFMMRQRHGR---IVNIASVVGVTGNPGQANYVAAKAGVIGLTKTS--AKELAS 174 Query: 174 SGVRLNAICPGFVNTAILESIEK 196 + +NAI PGF+ T + + +++ Sbjct: 175 RNITVNAIAPGFIATDMTDVLDE 197 >4M8S-A nrPDB Length = 248 Score = 101 bits (252), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 70/203 (34%), Positives = 114/203 (56%), Gaps = 17/203 (8%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 ++GK+ALVTGA++GIG A A+ L GAKV + E+G AA+ E+ Sbjct: 6 LSGKIALVTGASRGIGAAIADTLAAAGAKV-IGTATSESGA---AAISERLAQWGGEGRV 61 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVISG 114 + A+ + + + + FG+LDILVNNAG+ E+ W+ +Q+NL SV Sbjct: 62 LNSAEPETVENLIADIEKTFGKLDILVNNAGITRDNLLMRMKEEEWDDIMQVNLKSVFRA 121 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 + L M KQ G IIN++S+ G+M A Q Y A+K G++GF++S +A + + Sbjct: 122 SKAVLRGMMKQRAGR---IINITSVVGVMGNAGQTNYAAAKAGLIGFSKS--MAREVGSR 176 Query: 175 GVRLNAICPGFVNTAILESIEKE 197 G+ +N + PGF++T + ++ +E Sbjct: 177 GITVNCVAPGFIDTDMTRALPEE 199 >2Q2Q-A nrPDB Length = 255 Score = 101 bits (251), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 69/198 (34%), Positives = 101/198 (51%), Gaps = 17/198 (8%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 + GK ALVTG+ GIG A+ L GA + L + G A + K + Sbjct: 2 LKGKTALVTGSTSGIGLGIAQVLARAGANIVLNGF----GDPAPALAEIARHGVKAVHHP 57 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVISG 114 D++D Q+ F FG +DILVNNAG+ + ++W+K + +NL +V G Sbjct: 58 ADLSDVAQIEALFALAEREFGGVDILVNNAGIQHVAPVEQFPLESWDKIIALNLSAVFHG 117 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 T L L M +N G IIN++S+ GL+ + Y A+KHG+VG T+ L S Sbjct: 118 TRLALPGMRARNWGR---IINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGL--ETATS 172 Query: 175 GVRLNAICPGFVNTAILE 192 V NAICPG+V T +++ Sbjct: 173 NVTCNAICPGWVLTPLVQ 190 >4RZH-A nrPDB Length = 247 Score = 100 bits (250), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 69/204 (33%), Positives = 115/204 (56%), Gaps = 16/204 (7%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQF-EPQKTLFI 61 + +VALVTGA++GIG+A A AL G KV +V++ ++ A + E + + + Sbjct: 4 LTAQVALVTGASRGIGKATALALAATGMKV-VVNY-AQSSTAADAVVAEIIANGGEAIAV 61 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVIS 113 Q +VA+ ++ + +D F R+D+LVNNAG+ + ++W+ + +NL V Sbjct: 62 QANVANADEVDQLIKTTLDKFSRIDVLVNNAGITRDTLLLRMKLEDWQAVIDLNLTGVFL 121 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 T M KQ G IIN++S+AG+M Q Y A+K G++GFT++ +A L + Sbjct: 122 CTKAVSKLMLKQKSGR---IINITSVAGMMGNPGQANYSAAKAGVIGFTKT--VAKELAS 176 Query: 174 SGVRLNAICPGFVNTAILESIEKE 197 GV +NA+ PGF+ T + E++ E Sbjct: 177 RGVTVNAVAPGFIATDMTENLNAE 200 >2EW8-A nrPDB Length = 249 Score = 100 bits (249), Expect = 7e-22, Method: Compositional matrix adjust. Identities = 70/198 (35%), Positives = 109/198 (55%), Gaps = 21/198 (10%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 K+A++TG A GIGRA AE ++GA +A+ D L + +AA+ ++ L ++CDV Sbjct: 8 KLAVITGGANGIGRAIAERFAVEGADIAIAD--LVPAPEAEAAIRNL--GRRVLTVKCDV 63 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISGTYL 117 + + ++V+ FGR DILVNNAG+ + W+KT +IN V SG + Sbjct: 64 SQPGDVEAFGKQVISTFGRCDILVNNAGIYPLIPFDELTFEQWKKTFEIN---VDSGFLM 120 Query: 118 GLDYMS--KQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSG 175 ++ K+NG G IIN++S + + Y ++K +GFTR ALA++L G Sbjct: 121 AKAFVPGMKRNG--WGRIINLTSTTYWLKIEAYTHYISTKAANIGFTR--ALASDLGKDG 176 Query: 176 VRLNAICPGFVNTAILES 193 + +NAI P V TA E+ Sbjct: 177 ITVNAIAPSLVRTATTEA 194 >2PNF-A nrPDB Length = 248 Score = 98.6 bits (244), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 75/247 (30%), Positives = 120/247 (48%), Gaps = 26/247 (10%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQ--KT 58 + + GKV+LVTG+ +GIGRA AE L G+ V + +G + KA +E K Sbjct: 3 IKLQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITG---TSGERAKAVAEEIANKYGVKA 59 Query: 59 LFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEK--------NWEKTLQINLVS 110 ++ ++ ++ + F ++ + +DILVNNAG+ +K +WE+ L++NL Sbjct: 60 HGVEMNLLSEESINKAFEEIYNLVDGIDILVNNAGITRDKLFLRMSLLDWEEVLKVNLTG 119 Query: 111 VISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAAN 170 T L M KQ G I+N+SS+ G Q Y +K G++GFT+S LA Sbjct: 120 TFLVTQNSLRKMIKQRWGR---IVNISSVVGFTGNVGQVNYSTTKAGLIGFTKS--LAKE 174 Query: 171 LMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLI 230 L V +NA+ PGF+ T + + + E K K+ I P +AN ++ Sbjct: 175 LAPRNVLVNAVAPGFIETDMTAVLSE--------EIKQKYKEQIPLGRFGSPEEVANVVL 226 Query: 231 TLIEDDA 237 L + A Sbjct: 227 FLCSELA 233 >3EMK-A nrPDB Length = 246 Score = 98.6 bits (244), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 71/211 (33%), Positives = 113/211 (53%), Gaps = 23/211 (10%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 + G+ ALVTGA G+G A A AL +GA V L E + A L E+ Sbjct: 5 LTGRKALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELGERI-----FVFP 59 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISG 114 +++D++ ++ +K + G +DILVNNAG+ ++++W+ L +NL SV + Sbjct: 60 ANLSDREAVKALGQKAEEEMGGVDILVNNAGITRDGLFVRMSDEDWDAVLTVNLTSVFNL 119 Query: 115 TY-LGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 T L M ++NG IIN++S+ G+ Q YCASK G++GF++S LA + + Sbjct: 120 TRELTHPMMRRRNG----RIINITSIVGVTGNPGQANYCASKAGLIGFSKS--LAQEIAS 173 Query: 174 SGVRLNAICPGFVNTAI---LESIEKEENMG 201 V +N I PGF+ +A+ L +K+ MG Sbjct: 174 RNVTVNCIAPGFIESAMTGKLNEKQKDAIMG 204 >5CDY-A nrPDB Length = 244 Score = 98.6 bits (244), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 66/209 (31%), Positives = 104/209 (49%), Gaps = 18/209 (8%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M GK+ALVTGA++GIGRA AE L+ +GA V + + A L E + Sbjct: 1 MSFEGKIALVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGKG----- 55 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEK--------NWEKTLQINLVSVI 112 + +V D + + FG +DILVNNAG+ + W+ + NL SV Sbjct: 56 LMLNVVDPTSIDTVLATIRAEFGEVDILVNNAGITRDNLLMRMKDDEWQDIIDTNLTSVF 115 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + + M K+ G II + S+ G M A Q Y A+K G++GF++S LA + Sbjct: 116 RLSKAVMRAMMKKRFGR---IITIGSVVGTMGNAGQVNYAAAKAGVIGFSKS--LAREVA 170 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMG 201 + G+ +N + PGF+ T + ++ ++ G Sbjct: 171 SRGITVNVVAPGFIETDMTRTLTDDQRAG 199 >4NBV-A nrPDB Length = 246 Score = 98.2 bits (243), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 73/202 (36%), Positives = 107/202 (52%), Gaps = 15/202 (7%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M + G+VA++TGAA GIG A A+ GA V L D EA V+ AA + + Sbjct: 1 MKLQGRVAIITGAAAGIGFATAQRFAEDGAIVVLCDVQ-EARVREAAARLAATGATVSAY 59 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVI 112 + DV + ++ V+ R+DILVNNAG+ E ++ + +NL V Sbjct: 60 -RVDVTRRDEVDAMVAAVLAAHQRVDILVNNAGITKDARLAKMTEAQFDAVIDVNLKGVF 118 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + M++Q G +I+N SS+ GL Q Y ASK G++GFT++ A L Sbjct: 119 NCAQAVAGLMTEQGKG---VILNASSVVGLYGNFGQTNYAASKFGVIGFTKT--WARELG 173 Query: 173 NSGVRLNAICPGFVNTAILESI 194 GVR+NA+CPGFVNT IL+++ Sbjct: 174 PKGVRVNAVCPGFVNTEILQTV 195 >4NBT-A nrPDB Length = 240 Score = 97.4 bits (241), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 67/204 (32%), Positives = 105/204 (51%), Gaps = 22/204 (10%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 + GKVA++TG A+G+G+A A A +GAKV D D + + Sbjct: 3 KLEGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDLG-----------DLTYSHPNVEGM 51 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVIS 113 +V D + ++ V+D +G++DILVNNAG+ E W+ + +NL V + Sbjct: 52 YLNVTDVTGVEKFYQSVIDKYGKIDILVNNAGITKDAMTRKMTEAQWDAVIDVNLKGVFN 111 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 T L M Q G G II N+SS+ G+ Q Y A+K G++G T + A L Sbjct: 112 LTRLVGPQM--QTNGYGSII-NISSVVGVFGNIGQANYAATKAGVIGLTMTWAKEFALKG 168 Query: 174 SGVRLNAICPGFVNTAILESIEKE 197 + VR+NAI PG++ T IL+++ ++ Sbjct: 169 ANVRVNAIAPGYIMTDILKTVPQD 192 >2CFC-A nrPDB Length = 250 Score = 97.1 bits (240), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 72/251 (28%), Positives = 126/251 (50%), Gaps = 25/251 (9%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 +VA+VTGA+ G G A A L +G +VA +D + E ++ A K L ++ DV Sbjct: 3 RVAIVTGASSGNGLAIATRFLARGDRVAALDLSAET-LEETARTHWHAYADKVLRVRADV 61 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGV--NNE---------KNWEKTLQINLVSVISG 114 AD+ + ++ FG +D+LVNNAG+ N+E + ++K + +N+ + G Sbjct: 62 ADEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVRGIFLG 121 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 L +M Q G+I+N++S+A L+ + Y SK ++ T+S +A + S Sbjct: 122 CRAVLPHMLLQG---AGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKS--VAVDYAGS 176 Query: 175 GVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIE 234 G+R NA+CPG + T + + + E +D + I I +A+ ++ L Sbjct: 177 GIRCNAVCPGMIETPMTQWRLDQP------ELRDQVLARIPQKEIGTAAQVADAVMFLAG 230 Query: 235 DDA--LNGAIM 243 +DA +NGA + Sbjct: 231 EDATYVNGAAL 241 >3UVE-A nrPDB Length = 286 Score = 97.1 bits (240), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 73/214 (34%), Positives = 102/214 (47%), Gaps = 27/214 (12%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDW--NLEAGV---QCKAALDEQFEP-- 55 V GKVA VTGAA+G GR+ A L +GA + VD + AGV A+ E Sbjct: 9 VEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDLAETA 68 Query: 56 -------QKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN---------EKN 99 ++ + + DV D L+ V+ GRLDI+V NAG+ N E++ Sbjct: 69 DLVKGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNGGDTLDKTSEED 128 Query: 100 WEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIV 159 W + + INL V G+ +M GG GG II SS+ GL Y A+KHG+V Sbjct: 129 WTEMIDINLAGVWKTVKAGVPHMIA--GGRGGSIILTSSVGGLKAYPHTGHYVAAKHGVV 186 Query: 160 GFTRSAALAANLMNSGVRLNAICPGFVNTAILES 193 G R A L +R+N++ P V T +L + Sbjct: 187 GLMR--AFGVELGQHMIRVNSVHPTHVKTPMLHN 218 >3V2H-A nrPDB Length = 281 Score = 97.1 bits (240), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 66/197 (33%), Positives = 97/197 (49%), Gaps = 17/197 (8%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDE--QFEPQKTLFIQC 63 K A++TG+ GIG A A L GA + L + A + + DE L Sbjct: 26 KTAVITGSTSGIGLAIARTLAKAGANIVLNGFG--APDEIRTVTDEVAGLSSGTVLHHPA 83 Query: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISGT 115 D+ ++ D V D FG DILVNNAGV + W++ + +NL S Sbjct: 84 DMTKPSEIADMMAMVADRFGGADILVNNAGVQFVEKIEDFPVEQWDRIIAVNLSSSFHTI 143 Query: 116 YLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSG 175 + M K+ G IIN++S GL+ + Y A+KHGI+G T++ AL + SG Sbjct: 144 RGAIPPMKKKGWGR---IINIASAHGLVASPFKSAYVAAKHGIMGLTKTVAL--EVAESG 198 Query: 176 VRLNAICPGFVNTAILE 192 V +N+ICPG+V T ++E Sbjct: 199 VTVNSICPGYVLTPLVE 215 >3WOH-A nrPDB Length = 251 Score = 95.1 bits (235), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 65/203 (32%), Positives = 109/203 (53%), Gaps = 20/203 (9%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 ++GKVALVTG ++G+GRA A L GA VA+V + ++ + E+ + + Sbjct: 9 LSGKVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLGGTARSY-R 67 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSV--- 111 CDV+D +Q+ + V G +DILVNNAG+ +++++ + NL Sbjct: 68 CDVSDAEQVTRCVKAVTADLGPVDILVNNAGIIRDGLAASIKDEDYDAVMNTNLKGAFLF 127 Query: 112 ISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANL 171 I Y G ++ K++G IIN+SS++G+ A Q Y ++K G++G T+S +A L Sbjct: 128 IKACYFG--FIRKRSGS----IINISSVSGVFGSAGQANYASAKAGLIGLTKS--IAKEL 179 Query: 172 MNSGVRLNAICPGFVNTAILESI 194 VR NA+ PG + T + + + Sbjct: 180 AERNVRCNAVAPGLIATDMTQDL 202 >3WTC-A nrPDB Length = 262 Score = 94.7 bits (234), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 73/223 (32%), Positives = 111/223 (49%), Gaps = 18/223 (8%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M ++GK+A VTGAAQGIG+A A L GA V L+D ++ + A + + ++ + Sbjct: 4 MSLSGKIAAVTGAAQGIGKAIALRLAKDGADVILLD--VKQDTLAETAKEVEALGRRAVA 61 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEK--------NWEKTLQINLVSVI 112 + D++++ Q R T G LDI+VNNAG+ K EK IN+ V+ Sbjct: 62 LTADISNRDQFRSTLADAAKTLGGLDIMVNNAGICQVKPILDIEPAEIEKIFSINVQGVL 121 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 G ++ G G IIN S+AG Y A+K + T+SA A L Sbjct: 122 WGMQAAATLFKEK--GTKGKIINACSIAGHEGYPLLGAYSATKFAVRALTQSA--AKELA 177 Query: 173 NSGVRLNAICPGFVNTAILESIEKE--ENMGQYI--EYKDHIK 211 +SG+ +N+ CPG V T + +I+K E G I YK +++ Sbjct: 178 SSGITVNSYCPGIVGTDMWVTIDKRMAEITGTEIGATYKKYVE 220 >2C07-A nrPDB Length = 285 Score = 94.4 bits (233), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 66/202 (32%), Positives = 108/202 (53%), Gaps = 19/202 (9%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDE--QFEPQKTLFIQC 63 KVALVTGA +GIGR A+ L + V + ++ C + +DE F + + + Sbjct: 45 KVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKS---CDSVVDEIKSFGYESSGY-AG 100 Query: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE------KN--WEKTLQINLVSVISGT 115 DV+ ++++ + K++ +DILVNNAG+ + KN WE L+ NL S+ Sbjct: 101 DVSKKEEISEVINKILTEHKNVDILVNNAGITRDNLFLRMKNDEWEDVLRTNLNSLF--- 157 Query: 116 YLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSG 175 Y+ + G IIN+SS+ GL Q Y +SK G++GFT+S LA L + Sbjct: 158 YITQPISKRMINNRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKS--LAKELASRN 215 Query: 176 VRLNAICPGFVNTAILESIEKE 197 + +NAI PGF+++ + + I ++ Sbjct: 216 ITVNAIAPGFISSDMTDKISEQ 237 >1GEG-A nrPDB Length = 256 Score = 93.2 bits (230), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 69/211 (32%), Positives = 105/211 (49%), Gaps = 16/211 (7%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 KVALVTGA QGIG+A A L+ G VA+ D+N + +++ + ++ DV Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQA--GGHAVAVKVDV 60 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWE--------KTLQINLVSVISGTYL 117 +D+ Q+ + G D++VNNAGV E K IN+ VI G Sbjct: 61 SDRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWGIQA 120 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 ++ K+ G GG IIN S AG + + VY +SK + G T++AA +L G+ Sbjct: 121 AVEAFKKE--GHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAAR--DLAPLGIT 176 Query: 178 LNAICPGFVNTAILESIEKE--ENMGQYIEY 206 +N CPG V T + I+++ E G+ + Y Sbjct: 177 VNGYCPGIVKTPMWAEIDRQVSEAAGKPLGY 207 >1NFF-A nrPDB Length = 260 Score = 92.0 bits (227), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 69/205 (33%), Positives = 103/205 (50%), Gaps = 20/205 (9%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 + GKVALV+G A+G+G + A++ +GAKV D E G A L + ++ Sbjct: 4 RLTGKVALVSGGARGMGASHVRAMVAEGAKVVFGDILDEEGKAMAAELADAAR-----YV 58 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVIS 113 DV Q + V FG L +LVNNAG+ N W++ L +NL + Sbjct: 59 HLDVTQPAQWKAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNL----T 114 Query: 114 GTYLGLDYMSKQNGGEG-GIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 G +LG+ + K G G IIN+SS+ GL Y A+K + G T+S AL L Sbjct: 115 GVFLGIRAVVKPMKEAGRGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTAL--ELG 172 Query: 173 NSGVRLNAICPGFVNTAILESIEKE 197 SG+R+N+I PG V T + + + ++ Sbjct: 173 PSGIRVNSIHPGLVKTPMTDWVPED 197 >3RWB-A nrPDB Length = 247 Score = 91.7 bits (226), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 70/229 (30%), Positives = 109/229 (47%), Gaps = 27/229 (11%) Query: 5 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64 GK ALVTGAAQGIG+A A L GA V + D N E A++ +K I D Sbjct: 6 GKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASIG-----KKARAIAAD 60 Query: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVISGTY 116 ++D ++ F ++ G +DILVNNA + + +W K + +NL T Sbjct: 61 ISDPGSVKALFAEIQALTGGIDILVNNASIVPFVAWDDVDLDHWRKIIDVNLTGTFIVTR 120 Query: 117 LGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGV 176 G D M + G+ G +I+++S Y A+K G++GFTR ALA L + Sbjct: 121 AGTDQM--RAAGKAGRVISIASNTFFAGTPNMAAYVAAKGGVIGFTR--ALATELGKYNI 176 Query: 177 RLNAICPGFVNTAILESIEKEENMGQYIEY---------KDHIKDMIKY 216 NA+ PG + + +++ E G ++E +HI D++ + Sbjct: 177 TANAVTPGLIESDGVKASPHNEAFG-FVEMLQAMKGKGQPEHIADVVSF 224 >3LYL-A nrPDB Length = 247 Score = 90.9 bits (224), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 74/251 (29%), Positives = 119/251 (47%), Gaps = 35/251 (13%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQ---- 56 M +N KVALVTGA++GIG A AL KGA V G A E+FE Sbjct: 1 MSLNEKVALVTGASRGIGFEVAHALASKGATV--------VGTATSQASAEKFENSMKEK 52 Query: 57 --KTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQI 106 K + +++D + +++ F ++ +DILVNNAG+ +E W+ + Sbjct: 53 GFKARGLVLNISDIESIQNFFAEIKAENLAIDILVNNAGITRDNLMMRMSEDEWQSVINT 112 Query: 107 NLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAA 166 NL S+ + + M K+ G II++ S+ G Q YCA+K G++GF++S Sbjct: 113 NLSSIFRMSKECVRGMMKKRWGR---IISIGSVVGSAGNPGQTNYCAAKAGVIGFSKS-- 167 Query: 167 LAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIA 226 LA + + + +N + PGF+ T + + + E+ K I I I +P IA Sbjct: 168 LAYEVASRNITVNVVAPGFIATDMTDKLTDEQ--------KSFIATKIPSGQIGEPKDIA 219 Query: 227 NGLITLIEDDA 237 + L ++A Sbjct: 220 AAVAFLASEEA 230 >3OEC-A nrPDB Length = 317 Score = 90.9 bits (224), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 67/205 (32%), Positives = 99/205 (48%), Gaps = 22/205 (10%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDW-----NLEAGVQCKAALDE----- 51 + GKVA +TGAA+G GR A L GA + +D NL+ L E Sbjct: 43 RLQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKETVRLV 102 Query: 52 QFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKT 103 + + ++ + Q DV D L+ + + FG +DILV+N G++N+ + W Sbjct: 103 EEQGRRIIARQADVRDLASLQAVVDEALAEFGHIDILVSNVGISNQGEVVSLTDQQWSDI 162 Query: 104 LQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTR 163 LQ NL+ L M ++ G+GG +I +SS GL Q Y ASKHG+ G Sbjct: 163 LQTNLIGAWHACRAVLPSMIER--GQGGSVIFVSSTVGLRGAPGQSHYAASKHGVQGLML 220 Query: 164 SAALAANLMNSGVRLNAICPGFVNT 188 S LA + +R+N++ PG VNT Sbjct: 221 S--LANEVGRHNIRVNSVNPGAVNT 243 >2NM0-A nrPDB Length = 253 Score = 89.7 bits (221), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 68/247 (27%), Positives = 118/247 (47%), Gaps = 30/247 (12%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 + LVTG +GIG A A A G KVA+ + E P+ L ++CD+ Sbjct: 22 RSVLVTGGNRGIGLAIARAFADAGDKVAITYRSGE-------------PPEGFLAVKCDI 68 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMSKQ 125 D +Q+ ++++ + G +++L+ NAGV ++ + + + SV+ G + K+ Sbjct: 69 TDTEQVEQAYKEIEETHGPVEVLIANAGVTKDQLLMRMSEEDFTSVVETNLTGTFRVVKR 128 Query: 126 NG-----GEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNA 180 + G ++ +SS+ GL+ A Q Y ASK G+VGF RS LA L + + N Sbjct: 129 ANRAMLRAKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARS--LARELGSRNITFNV 186 Query: 181 ICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDA--L 238 + PGFV+T + + + E+ + +I + P IA + L DDA + Sbjct: 187 VAPGFVDTDMTKVLTDEQ--------RANIVSQVPLGRYARPEEIAATVRFLASDDASYI 238 Query: 239 NGAIMKI 245 GA++ + Sbjct: 239 TGAVIPV 245 >2CDH-G nrPDB Length = 244 Score = 88.2 bits (217), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 61/192 (31%), Positives = 102/192 (53%), Gaps = 22/192 (11%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAA--LDEQFEPQ--KTLFIQ 62 V +VTGA++GIG+A A +L G KV LV++ A KAA + +Q E + + Sbjct: 3 VVVVTGASRGIGKAIALSLGKAGCKV-LVNYARSA----KAAEEVSKQIEAYGGQAITFG 57 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVISG 114 DV+ + + + +D +G +D++VNNAG+ + W++ + +NL V Sbjct: 58 GDVSKEADVEAMMKTAIDAWGTIDVVVNNAGITRDTLLIRMKKSQWDEVIDLNLTGVFLC 117 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 T M K+ G IIN++S+ GL+ Q Y A+K G++GF+++AA N Sbjct: 118 TQAATKIMMKKRKGR---IINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRN- 173 Query: 175 GVRLNAICPGFV 186 + +N +CPGF+ Sbjct: 174 -INVNVVCPGFI 184 >2O23-A nrPDB Length = 265 Score = 88.2 bits (217), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 73/262 (27%), Positives = 120/262 (45%), Gaps = 35/262 (13%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 V G VA++TG A G+G A AE L+ +GA L+D G L +F Sbjct: 10 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLG-----NNCVFAP 64 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------------NNEKNWEKTLQINL 108 DV ++ ++ FGR+D+ VN AG+ + +++++ L +NL Sbjct: 65 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 124 Query: 109 VSVISGTYLGLDYMSKQ---NGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSA 165 + + L M + GG+ G+IIN +S+A Q Y ASK GIVG T Sbjct: 125 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP- 183 Query: 166 ALAANLMNSGVRLNAICPGFVNTAILESI-EKEEN-MGQYIEYKDHIKDMIKYYGILDPP 223 +A +L G+R+ I PG T +L S+ EK N + + + + D +Y ++ Sbjct: 184 -IARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQ-- 240 Query: 224 LIANGLITLIEDDALNGAIMKI 245 +IE+ LNG ++++ Sbjct: 241 -------AIIENPFLNGEVIRL 255 >1B15-A nrPDB Length = 254 Score = 87.0 bits (214), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 54/185 (29%), Positives = 94/185 (50%), Gaps = 12/185 (6%) Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLD 120 + VA+ ++L +K+ D +DIL+N AG+ ++ E+T+ IN +++ T LD Sbjct: 64 VTVPVAESKKL---LKKIFDQLKTVDILINGAGILDDHQIERTIAINFTGLVNTTTAILD 120 Query: 121 YMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNA 180 + K+ GG GGII N+ S+ G + Q PVY ASK +V FT S A A + +GV + Sbjct: 121 FWDKRKGGPGGIIANICSVTGFNAIHQVPVYSASKAAVVSFTNSLAKLAPI--TGVTAYS 178 Query: 181 ICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNG 240 I PG T ++ + +++ + + +++ + + IE + NG Sbjct: 179 INPGITRTPLVHT------FNSWLDVEPRVAELLLSHPTQTSEQCGQNFVKAIEANK-NG 231 Query: 241 AIMKI 245 AI K+ Sbjct: 232 AIWKL 236 >5EJ2-A nrPDB Length = 308 Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 66/209 (31%), Positives = 99/209 (47%), Gaps = 23/209 (11%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDW-----NLEAGVQCKAALDEQFE-- 54 V GKVA ++GAA+G GR+ A L +GA + +D NL L E + Sbjct: 34 RVAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETADLV 93 Query: 55 ---PQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKN---------WEK 102 ++ + Q DV D + L+ V+ GRLDI+V NAGV + W+ Sbjct: 94 KDLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTDGRKLHKIRDNVWQD 153 Query: 103 TLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFT 162 + INL V G+ ++ +GG GG I+ SS+ G Y A+KHG++G Sbjct: 154 MIDINLTGVWHTVKAGVPHV--LSGGRGGSIVLTSSVGGRKAYPNTGHYIAAKHGVIGLM 211 Query: 163 RSAALAANLMNSGVRLNAICPGFVNTAIL 191 R A A L +R+NA+ P V+T ++ Sbjct: 212 R--AFAVELGPHMIRVNAVLPTQVSTTMV 238 >3FTP-A nrPDB Length = 270 Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 64/203 (31%), Positives = 104/203 (51%), Gaps = 19/203 (9%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQ--FEPQKTLFIQC 63 +VA+VTGA++GIGRA A L +GA V + EAG + A +Q E + + Sbjct: 29 QVAIVTGASRGIGRAIALELARRGAMV-IGTATTEAGAEGIGAAFKQAGLEGRGAVL--- 84 Query: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEK--------NWEKTLQINLVSVISGT 115 +V D + + FG L++LVNNAG+ ++ W+ + NL +V + Sbjct: 85 NVNDATAVDALVESTLKEFGALNVLVNNAGITQDQLAMRMKDDEWDAVIDTNLKAVFRLS 144 Query: 116 YLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSG 175 L M K GG I+N++S+ G Q Y A+K G+ G TR ALA + + G Sbjct: 145 RAVLRPMMKARGGR---IVNITSVVGSAGNPGQVNYAAAKAGVAGMTR--ALAREIGSRG 199 Query: 176 VRLNAICPGFVNTAILESIEKEE 198 + +N + PGF++T + + + +E+ Sbjct: 200 ITVNCVAPGFIDTDMTKGLPQEQ 222 >4DBZ-A nrPDB Length = 281 Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 66/202 (32%), Positives = 96/202 (47%), Gaps = 15/202 (7%) Query: 4 NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQ-KTLFIQ 62 + +VALVTGA GIG A L +G +V + E + L E E + Sbjct: 25 DSEVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEG---LRTTLKELREAGVEADGRT 81 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVISG 114 CDV ++ VV+ +G +D+LVNNAG ++ W ++ NL V Sbjct: 82 CDVRSVPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELADELWLDVVETNLTGVFRV 141 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 T L G G I+N++S G + Y ASKHG+VGFT+ AL L + Sbjct: 142 TKQVLKAGGMLERGTG-RIVNIASTGGKQGLVHAAPYSASKHGVVGFTK--ALGLELART 198 Query: 175 GVRLNAICPGFVNTAILESIEK 196 G+ +NA+CPGFV T + S+ + Sbjct: 199 GITVNAVCPGFVETPMAASVRE 220 >3AUT-A nrPDB Length = 269 Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 62/197 (31%), Positives = 98/197 (49%), Gaps = 21/197 (10%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQ----KTLFI 61 KV ++TG + G+GRA A + AKV + +N E + ALD + E + + + + Sbjct: 16 KVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNE-----EEALDAKKEVEEAGGQAIIV 70 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVIS 113 Q DV ++ + + + + FG LD+++NNAGV N NW K + NL Sbjct: 71 QGDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGAFL 130 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 G+ + Y + + G +INMSS+ ++P Y ASK G+ T + LA Sbjct: 131 GSREAIKYFVEND--IKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTET--LALEYAP 186 Query: 174 SGVRLNAICPGFVNTAI 190 G+R+N I PG +NT I Sbjct: 187 KGIRVNNIGPGAMNTPI 203 >3V2G-A nrPDB Length = 271 Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 63/192 (32%), Positives = 98/192 (51%), Gaps = 7/192 (3%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + + GK A VTG ++GIG A A+ L L+GA VAL N Q + EQ + + Sbjct: 27 ISLAGKTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQ-AGGRAVA 85 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVIS----GTY 116 I+ D D + + R+ V+ G LDILVN+AG+ + E+T + V++ + Sbjct: 86 IRADNRDAEAIEQAIRETVEALGGLDILVNSAGIWHSAPLEETTVADFDEVMAVNFRAPF 145 Query: 117 LGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGV 176 + + S+ G G II S+LA L+P +Y ASK + G T+ LA +L G+ Sbjct: 146 VAIRSASRHLGDGGRIITIGSNLAELVPWPGISLYSASKAALAGLTK--GLARDLGPRGI 203 Query: 177 RLNAICPGFVNT 188 +N + PG +T Sbjct: 204 TVNIVHPGSTDT 215 >4CQL-A nrPDB Length = 261 Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 75/258 (29%), Positives = 127/258 (49%), Gaps = 32/258 (12%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAAL----DEQFEPQKT-LFI 61 +ALVTGA GIGRA + L +GA VA D + A + L ++ P+ Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72 Query: 62 QCDVADQQQLRDTFRKVVDHFGRL-DILVNNAGVN--------NEKNWEKTLQINLVSVI 112 Q DV++ + R +V F R ++V+ AG+ +E +W+K + +NL Sbjct: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNL---- 128 Query: 113 SGTYLGLDYMSKQ--NGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAAN 170 GT+L ++ + G G IIN+SS+ G + Q Y ASK G++G T++AA Sbjct: 129 KGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAR--E 186 Query: 171 LMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLI 230 L G+R N++ PGF+ T + + + + + D I +MI + DP +A+ + Sbjct: 187 LGRHGIRCNSVLPGFIATPMTQKVPQ--------KVVDKITEMIPMGHLGDPEDVADVVA 238 Query: 231 TLIEDDA--LNGAIMKIT 246 L +D+ + G +++T Sbjct: 239 FLASEDSGYITGTSVEVT 256 >4TRR-A nrPDB Length = 269 Score = 85.5 bits (210), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 65/200 (32%), Positives = 101/200 (50%), Gaps = 16/200 (8%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEP-QKTLF 60 ++NGK A+VTGAA GIG+ A L GA VA+ D N + A DE + K + Sbjct: 11 NLNGKTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDG---ANAVADEINKAGGKAIG 67 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVI 112 + DV +++ + KV + FG +DILV+NAG+ + +W+K I++ Sbjct: 68 VAMDVTNEEAVNTGIDKVAEAFGSVDILVSNAGIQIVNPIENYSFADWKKMQAIHVDGAF 127 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 T L +M K + GG++I M S+ + Y +KHG++G R LA Sbjct: 128 LTTKAALKHMYKDD--RGGVVIYMGSVHSHEASPLKSAYVTAKHGLLGLAR--VLAKEGA 183 Query: 173 NSGVRLNAICPGFVNTAILE 192 VR + +CPGFV T +++ Sbjct: 184 KHNVRSHVVCPGFVRTPLVD 203 >5OVJ-A nrPDB Length = 256 Score = 85.5 bits (210), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 62/242 (25%), Positives = 108/242 (44%), Gaps = 33/242 (13%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 + LVTG +GIG A A L G KVA+ A P +QCDV Sbjct: 25 RSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGA-------------PDDLFGVQCDV 71 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISGTYL 117 D + F++V +H G +++LV NAG++ E+ +E+ + NL Sbjct: 72 TDSAAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQR 131 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 M ++ G II + S++G+ + Q Y A+K G++G RS ++ L +GV Sbjct: 132 ASRTMQRKRFGR---IIFIGSVSGMWGIGNQANYAAAKAGLIGMARS--ISRELAKAGVT 186 Query: 178 LNAICPGFVNTAILESIEKEENMG--QYIEYK-----DHIKDMIKYYGILDPPLIANGLI 230 N + PG+++T + ++++ G +I K + + + + D IA +I Sbjct: 187 ANVVAPGYIDTEMTRALDERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVI 246 Query: 231 TL 232 + Sbjct: 247 PV 248 >5OVL-A nrPDB Length = 300 Score = 85.1 bits (209), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 62/242 (25%), Positives = 108/242 (44%), Gaps = 33/242 (13%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 + LVTG +GIG A A L G KVA+ A P +QCDV Sbjct: 69 RSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGA-------------PDDLFGVQCDV 115 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISGTYL 117 D + F++V +H G +++LV NAG++ E+ +E+ + NL Sbjct: 116 TDSAAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQR 175 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 M ++ G II + S++G+ + Q Y A+K G++G RS ++ L +GV Sbjct: 176 ASRTMQRKRFGR---IIFIGSVSGMWGIGNQANYAAAKAGLIGMARS--ISRELAKAGVT 230 Query: 178 LNAICPGFVNTAILESIEKEENMG--QYIEYK-----DHIKDMIKYYGILDPPLIANGLI 230 N + PG+++T + ++++ G +I K + + + + D IA +I Sbjct: 231 ANVVAPGYIDTEMTRALDERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVI 290 Query: 231 TL 232 + Sbjct: 291 PV 292 >3F9I-A nrPDB Length = 249 Score = 84.0 bits (206), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 60/206 (29%), Positives = 108/206 (52%), Gaps = 22/206 (10%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + + GK +L+TGA+ GIG A A L G+KV + N E AL + + + Sbjct: 10 IDLTGKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYTIE---- 65 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVI 112 C++A++++ + K + LDILV NAG+ ++ ++++K + INL + Sbjct: 66 -VCNLANKEECSNLISKTSN----LDILVCNAGITSDTLAIRMKDQDFDKVIDINLKA-- 118 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 L + + K G IIN+SS+ G+ Q YCASK G++G T+S L+ + Sbjct: 119 -NFILNREAIKKMIQKRYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKS--LSYEVA 175 Query: 173 NSGVRLNAICPGFVNTAILESIEKEE 198 G+ +NA+ PGF+ + + + + +++ Sbjct: 176 TRGITVNAVAPGFIKSDMTDKLNEKQ 201 >4IIN-A nrPDB Length = 271 Score = 83.6 bits (205), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 64/208 (30%), Positives = 98/208 (47%), Gaps = 20/208 (9%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDW-NLEAGVQCKAALDEQFEPQ--K 57 M GK L+TGA++GIG A+ L G KV W N + + AL + E + K Sbjct: 25 MQFTGKNVLITGASKGIGAEIAKTLASMGLKV----WINYRSNAEVADALKNELEEKGYK 80 Query: 58 TLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEK--------NWEKTLQINLV 109 I+ D A + + + +V G L LVNNAGV +K ++ + NL Sbjct: 81 AAVIKFDAASESDFIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLT 140 Query: 110 SVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAA 169 S G L MSK G ++N++S+ G Q Y ASK G++ ++S A Sbjct: 141 SAFIGCREALKVMSKSRFGS---VVNVASIIGERGNMGQTNYSASKGGMIAMSKSFAYEG 197 Query: 170 NLMNSGVRLNAICPGFVNTAILESIEKE 197 L N +R N++ PGF+ T + +++ E Sbjct: 198 ALRN--IRFNSVTPGFIETDMNANLKDE 223 >4Z9Y-A nrPDB Length = 253 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 64/211 (30%), Positives = 103/211 (48%), Gaps = 18/211 (8%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDW-NLEAGVQCKAALDEQFEPQKTLFI 61 + GKVAL+TG G+G+ A L G + V+ + ++ AL +F L + Sbjct: 8 LQGKVALITGCDTGLGQGMAIGLAQAGCDIVGVNIVEPKDTIEKVTALGRRF-----LSL 62 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVIS 113 D+++ + K V FG +DILVNNAG+ +EKNW+ + +N+ SV Sbjct: 63 TADMSNVSGHAELVEKAVAEFGHVDILVNNAGIIRREDAIEFSEKNWDDVMNLNIKSVFF 122 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 + KQ G+GG IIN++S+ + P Y ASK ++G TR +A Sbjct: 123 MSQTVARQFIKQ--GKGGKIINIASMLSFQGGIRVPSYTASKSAVMGVTR--LMANEWAK 178 Query: 174 SGVRLNAICPGFVNTAILESIEKEENMGQYI 204 G+ +NAI PG++ T + + +E + I Sbjct: 179 HGINVNAIAPGYMATNNTQQLRADEERSKEI 209 >4BO1-A nrPDB Length = 269 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 69/213 (32%), Positives = 103/213 (48%), Gaps = 18/213 (8%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M + GKVALVTGA++GIG+A A L GA V + + L L Sbjct: 23 MSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLV 82 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEK--------NWEKTLQINLVSVI 112 + DV+ + + T + H G+ I+VNNAG+ + W + NL S+ Sbjct: 83 L--DVSSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEWFDVVNTNLNSLY 140 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + L M+K G IIN+ S+ G M A Q Y A+K G+ GFTR ALA + Sbjct: 141 RLSKAVLRGMTKARWGR---IINIGSVVGAMGNAGQTNYAAAKAGLEGFTR--ALAREVG 195 Query: 173 NSGVRLNAICPGFVNTAI---LESIEKEENMGQ 202 + + +NA+ PGF++T + L ++E +GQ Sbjct: 196 SRAITVNAVAPGFIDTDMTRELPEAQREALLGQ 228 >3GRP-A nrPDB Length = 266 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 70/246 (28%), Positives = 122/246 (49%), Gaps = 32/246 (13%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI- 61 + G+ ALVTGA GIG A A +GA V L + + A L K +F+ Sbjct: 25 LTGRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADLG------KDVFVF 78 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVIS 113 +++D++ ++ +DILVNNAG+ + ++W+ L +NL + + Sbjct: 79 SANLSDRKSIKQLAEVAEREMEGIDILVNNAGITRDGLFVRMQDQDWDDVLAVNLTAAST 138 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 T + M ++ G IIN++S+ G++ Q YCA+K G++GF++ ALA + + Sbjct: 139 LTRELIHSMMRRRYGR---IINITSIVGVVGNPGQTNYCAAKAGLIGFSK--ALAQEIAS 193 Query: 174 SGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMI--KYYGILDPPLIANGLIT 231 + +N I PGF+ +A+ + + +++ K+ I MI K GI + IA + Sbjct: 194 RNITVNCIAPGFIKSAMTDKLNEKQ--------KEAIMAMIPMKRMGIGEE--IAFATVY 243 Query: 232 LIEDDA 237 L D+A Sbjct: 244 LASDEA 249 >2PH3-A nrPDB Length = 245 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 61/201 (30%), Positives = 100/201 (49%), Gaps = 15/201 (7%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVAL-VDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64 + AL+TGA++GIGRA A L G +A+ N E + + P + + + Sbjct: 2 RKALITGASRGIGRAIALRLAEDGFALAIHYGQNREKAEEVAEEARRRGSPLVAV-LGAN 60 Query: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVISGTY 116 + + + + + G LD LVNNAG+ + ++WE L+ NL +V T Sbjct: 61 LLEAEAATALVHQAAEVLGGLDTLVNNAGITRDTLLVRMKDEDWEAVLEANLSAVFRTTR 120 Query: 117 LGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGV 176 + M K G I+N++S+ G++ Q Y ASK G++GFTR A+A G+ Sbjct: 121 EAVKLMMKARFGR---IVNITSVVGILGNPGQANYVASKAGLIGFTR--AVAKEYAQRGI 175 Query: 177 RLNAICPGFVNTAILESIEKE 197 +NA+ PGF+ T + E + +E Sbjct: 176 TVNAVAPGFIETEMTERLPQE 196 >4IS3-A nrPDB Length = 268 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 54/194 (27%), Positives = 93/194 (47%), Gaps = 13/194 (6%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 V KV ++TG +GIG A A+ + GAKV++ E A L E + ++ L Sbjct: 23 VQDKVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYPEEEVLGFA 82 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISG 114 D+ + + +V +GRLD+++NNAG+ +E+ ++ + IN+ V +G Sbjct: 83 PDLTSRDAVMAAVGQVAQKYGRLDVMINNAGITSNNVFSRVSEEEFKHIMDINVTGVFNG 142 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 + M + G+IIN +S+ G+ Y ASK ++G T L ++ Sbjct: 143 AWCAYQCMKD---AKKGVIINTASVTGIFGSLSGVGYPASKASVIGLTH--GLGREIIRK 197 Query: 175 GVRLNAICPGFVNT 188 +R+ + PG VNT Sbjct: 198 NIRVVGVAPGVVNT 211 >4AVY-A nrPDB Length = 242 Score = 82.4 bits (202), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 63/193 (32%), Positives = 100/193 (51%), Gaps = 26/193 (13%) Query: 5 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEA-GVQCKAALDEQFEPQKTLFIQC 63 G+ LVTG + GIG A A GA+V V L+A GV + E + Sbjct: 11 GQQVLVTGGSSGIGAAIAMQFAELGAEV--VALGLDADGVHAPRHPRIRRE-------EL 61 Query: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEK------NWEKTLQINLVSVISGTYL 117 D+ D Q+L+ F + RLD+LVNNAG++ ++ +E+ L++NL + + + L Sbjct: 62 DITDSQRLQRLF----EALPRLDVLVNNAGISRDREEYDLATFERVLRLNLSAAMLASQL 117 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 ++++ GG I+N++S+ A +P Y ASK IV TRS LA +R Sbjct: 118 ARPLLAQR----GGSILNIASMYSTFGSADRPAYSASKGAIVQLTRS--LACEYAAERIR 171 Query: 178 LNAICPGFVNTAI 190 +NAI PG+++T + Sbjct: 172 VNAIAPGWIDTPL 184 >1E3W-A nrPDB Length = 261 Score = 81.6 bits (200), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 70/262 (26%), Positives = 124/262 (47%), Gaps = 35/262 (13%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDW-NLEAGVQCKAALDEQFEPQKTLFI 61 V G VA++TG A G+G + A+ L+ +GA L+D N E + K +F Sbjct: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGG------NCIFA 61 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV-------NNEKN-------WEKTLQIN 107 +V +++++ + FGR+D+ VN AG+ + +KN +++ + +N Sbjct: 62 PANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVN 121 Query: 108 LVSVISGTYLGLDYMSKQ---NGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRS 164 L+ + L M + GG+ G+IIN +S+A Q Y ASK GIVG T Sbjct: 122 LIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 Query: 165 AALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGIL-DPP 223 +A +L G+R+ I PG T +L ++ ++ + + + L DP Sbjct: 182 --IARDLAPIGIRVVTIAPGLFATPLLTTLPD--------TVRNFLASQVPFPSRLGDPA 231 Query: 224 LIANGLITLIEDDALNGAIMKI 245 A+ + +IE+ LNG ++++ Sbjct: 232 EYAHLVQMVIENPFLNGEVIRL 253 >3VZS-A nrPDB Length = 257 Score = 81.6 bits (200), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 63/206 (30%), Positives = 102/206 (49%), Gaps = 26/206 (12%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQF-EPQKTL---FI 61 ++A VTG GIG A + L G +V AG + E++ E QK L FI Sbjct: 15 RIAYVTGGMGGIGTAICQRLAKDGFRVV-------AGCGPNSPRREKWLEQQKALGFDFI 67 Query: 62 --QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSV 111 + +VAD + F KV G +D+L+NNAG+ + +W+ + NL S+ Sbjct: 68 ASEGNVADWDSTKTAFDKVKSEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSL 127 Query: 112 ISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANL 171 + T +D M+ + G I+N+SS+ G Q Y +K G+ GFT ALA + Sbjct: 128 FNVTKQVIDGMADRGWGR---IVNISSVNGQKGQFGQTNYSTAKAGLHGFT--MALAQEV 182 Query: 172 MNSGVRLNAICPGFVNTAILESIEKE 197 GV +N + PG++ T ++++I ++ Sbjct: 183 ATKGVTVNTVSPGYIATDMVKAIRQD 208 >5OJG-A nrPDB Length = 260 Score = 81.3 bits (199), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 68/199 (34%), Positives = 99/199 (49%), Gaps = 27/199 (13%) Query: 5 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFE--PQKTLFIQ 62 GKVA+VT A +GIG A AE LL +GA V + G + + +DE E K L Sbjct: 10 GKVAIVTAATKGIGLAIAERLLDEGASVVI-------GSRNQKNVDEAIEYLKNKGLTKV 62 Query: 63 CDVADQQQLRDTFRKVVD----HFGRLDILVNNAGVN---------NEKNWEKTLQINLV 109 +A D +K+VD FG+++ILVNN G+N +++ W+K ++N+ Sbjct: 63 AGIAGHIASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVK 122 Query: 110 SVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAA 169 + T L +++K+ G G II N S A P Y +K +VG TR ALA Sbjct: 123 AGFQMTKLVHPHIAKEGG--GAIIFNASYSAYKSPPG-IAAYGVTKTTLVGLTR--ALAM 177 Query: 170 NLMNSGVRLNAICPGFVNT 188 L +R+N I PG + T Sbjct: 178 GLAKDNIRVNGIAPGVIKT 196 >3V8B-A nrPDB Length = 283 Score = 80.5 bits (197), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 65/218 (29%), Positives = 101/218 (46%), Gaps = 18/218 (8%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQ-KTL 59 M+ VAL+TGA GIGRA A AL G V + + + DE + + Sbjct: 24 MNQPSPVALITGAGSGIGRATALALAADGVTVGALG---RTRTEVEEVADEIVGAGGQAI 80 Query: 60 FIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN---------NEKNWEKTLQINLVS 110 ++ DV+D+ Q+R+ R +V FG LDI+V NAG+N W++T+ +NL Sbjct: 81 ALEADVSDELQMRNAVRDLVLKFGHLDIVVANAGINGVWAPIDDLKPFEWDETIAVNLRG 140 Query: 111 VISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAAN 170 +L + Y+ KQ G GG I+ +SS+ G + LA Sbjct: 141 TFLTLHLTVPYL-KQRG--GGAIVVVSSINGTRTFTTPGATAYTATKAAQVAIVQQLALE 197 Query: 171 LMNSGVRLNAICPGFVNTAILES--IEKEENMGQYIEY 206 L +R+NA+CPG + T I ++ + EE +E+ Sbjct: 198 LGKHHIRVNAVCPGAIETNISDNTKLRHEEETAIPVEW 235 >5JS6-A nrPDB Length = 274 Score = 80.1 bits (196), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 56/181 (30%), Positives = 90/181 (49%), Gaps = 21/181 (11%) Query: 23 EALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVVDHF 82 A + GA+V + D + G AL+++ +FI CDV + ++ + + F Sbjct: 29 RAFVNSGARVVICDKDESGG----RALEQELP--GAVFILCDVTQEDDVKTLVSETIRRF 82 Query: 83 GRLDILVNNAG---------VNNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGII 133 GRLD +VNNAG + + + + L++NL+ + T L L Y+ K G + Sbjct: 83 GRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGN----V 138 Query: 134 INMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILES 193 IN+SSL G + AQ Y A+K + T+ ALA + GVR+N I PG + T + E Sbjct: 139 INISSLVGAIGQAQAVPYVATKGAVTAMTK--ALALDESPYGVRVNCISPGNIWTPLWEE 196 Query: 194 I 194 + Sbjct: 197 L 197 >3WYE-A nrPDB Length = 256 Score = 80.1 bits (196), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 65/200 (32%), Positives = 103/200 (51%), Gaps = 14/200 (7%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 KVALVTGA QGIG+A A L+ G VA+ D+N +A + A+ Q + ++ DV Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYN-DATAKAVASEINQ-AGGHAVAVKVDV 60 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISGTYL 117 +D+ Q+ + G D++VNNAG+ E++ ++ +N+ SV G Sbjct: 61 SDRDQVFAAVEQARKTLGGFDVIVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQA 120 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 ++ K+ G GG IIN +S+A + Y +K + G T++AA +L G+ Sbjct: 121 AVEAFKKE--GHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAAR--DLAPLGIT 176 Query: 178 LNAICPGFVNTAILESIEKE 197 +N CPG V T + E I+ E Sbjct: 177 VNGYCPGIVGTGMWEQIDAE 196 >4RGB-A nrPDB Length = 294 Score = 80.1 bits (196), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 71/271 (26%), Positives = 133/271 (49%), Gaps = 35/271 (12%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAG-VQCKAALDEQFEP------ 55 ++G+V +TGAA+G GR+ A +GA + VD + V K E+ E Sbjct: 23 LDGRVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEETARLVE 82 Query: 56 ---QKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV----NNEKNWEKTLQINL 108 Q+ LF + DV D+ L++ F V+ FG +D ++ NAGV +E++ + L++ L Sbjct: 83 KTGQEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLTNPDERDASEALRLGL 142 Query: 109 VSVISGTY----LGLDYMSKQNGGEGGIIINMSSLAGLMPVAQ----QPVYCASKHGIVG 160 ++ G + + + +M ++ G+GG +I SS+ L+ + Y SK I G Sbjct: 143 DIMLIGVWNTFQVAIPHMKER--GQGGNLIATSSMIALLDLTDGRGGTDAYLTSKLAITG 200 Query: 161 FTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKY---- 216 RS AL L +R+N + P +T + I + + + IE H+ + + Sbjct: 201 LVRSYALM--LAADRIRVNGVAPTNCSTPM---ITENPALFKVIEENPHLVNAMSTALPD 255 Query: 217 YGILDPPLIANGLITLIED--DALNGAIMKI 245 + +++P ++N ++ LI D + G+++K+ Sbjct: 256 FPMIEPRDVSNAILFLISDAGRSFTGSVLKV 286 >3T7C-A nrPDB Length = 299 Score = 79.7 bits (195), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 76/265 (28%), Positives = 119/265 (44%), Gaps = 38/265 (14%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEA-GVQCKAALDE-------QFE 54 V GKVA +TGAA+G GR+ A L +GA + +D + GV+ + + Q E Sbjct: 26 VEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETVRQVE 85 Query: 55 P--QKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE---------KNWEKT 103 ++ + Q DV D ++ V GRLDI++ NA + +E K W Sbjct: 86 ALGRRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRMDPKTWRDM 145 Query: 104 LQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTR 163 + +NL + + ++ G GG I+ SS+ GL Y ASKHG+ G R Sbjct: 146 IDVNLNGAWITARVAIPHI--MAGKRGGSIVFTSSIGGLRGAENIGNYIASKHGLHGLMR 203 Query: 164 SAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDM---------- 213 + AL N +R+N +CP V T +L + E M + ++D Sbjct: 204 TMALELGPRN--IRVNIVCPSSVATPMLLN-EPTYRMFRPDLENPTVEDFQVASRQMHVL 260 Query: 214 -IKYYGILDPPLIANGLITLIEDDA 237 I Y ++P I+N ++ L+ DDA Sbjct: 261 PIPY---VEPADISNAILFLVSDDA 282 >1UZM-A nrPDB Length = 247 Score = 79.3 bits (194), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 67/258 (25%), Positives = 115/258 (44%), Gaps = 40/258 (15%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 + LVTG +GIG A A+ L G KVA+ A P+ ++ DV Sbjct: 16 RSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGA-------------PKGLFGVEVDV 62 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISGTYL 117 D + F V +H G +++LV+NAG++ E+ +EK + NL Sbjct: 63 TDSDAVDRAFTAVEEHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQR 122 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 M + G +I + S++GL + Q Y ASK G++G RS +A L + V Sbjct: 123 ASRSMQRNKFGR---MIFIGSVSGLWGIGNQANYAASKAGVIGMARS--IARELSKANVT 177 Query: 178 LNAICPGFVNTAILESIEKEENMG--QYIEYKDHIKDMIKYYGILDPPLIANGLITLIED 235 N + PG+++T + ++++ G Q+I K + P +A + L + Sbjct: 178 ANVVAPGYIDTDMTRALDERIQQGALQFIPAKR----------VGTPAEVAGVVSFLASE 227 Query: 236 DA--LNGAIMKITTSKGI 251 DA ++GA++ + G+ Sbjct: 228 DASYISGAVIPVDGGMGM 245 >1YXM-A nrPDB Length = 303 Score = 79.3 bits (194), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 65/217 (29%), Positives = 105/217 (48%), Gaps = 32/217 (14%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDE---QFEPQK-- 57 + G+VA+VTG A GIG+A + LL G+ V + LE + K+A DE P K Sbjct: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLE---RLKSAADELQANLPPTKQA 72 Query: 58 -TLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINL 108 + IQC++ +++++ + + +D FG+++ LVNN G + K W L+ NL Sbjct: 73 RVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNL 132 Query: 109 VSVISGTYLGLDYMSKQNGGEGGIIINM--SSLAGLMPVAQQPVYCASKHGIVGFTRSAA 166 Y+ S GG I+N+ + AG P+A A++ G+ T+S Sbjct: 133 TGTF---YMCKAVYSSWMKEHGGSIVNIIVPTKAGF-PLAVHS--GAARAGVYNLTKS-- 184 Query: 167 LAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQY 203 LA SG+R+N + PG ++ S EN G + Sbjct: 185 LALEWACSGIRINCVAPG-----VIYSQTAVENYGSW 216 >4MOW-A nrPDB Length = 256 Score = 79.3 bits (194), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 65/196 (33%), Positives = 102/196 (52%), Gaps = 24/196 (12%) Query: 5 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQC-KAALDEQFEPQKTLFIQC 63 GKVA+VTGA++GIG A A+AL +GA V + + +AG +A+ E + + + Sbjct: 14 GKVAIVTGASKGIGAAIAKALADEGAAVVVNYASSKAGADAVVSAITEA--GGRAVAVGG 71 Query: 64 DV---ADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVI 112 DV AD Q++ DT ++ +GRLD+LVNN+GV E+++ + N+ V+ Sbjct: 72 DVSKAADAQRIVDT---AIETYGRLDVLVNNSGVYEFAPIEAITEEHYRRQFDTNVFGVL 128 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 T + ++ GEG IIN+SS+ + VY +K + T LA L Sbjct: 129 LTTQAAVKHL-----GEGASIINISSVVTSITPPASAVYSGTKGAVDAIT--GVLALELG 181 Query: 173 NSGVRLNAICPGFVNT 188 +R+NAI PG + T Sbjct: 182 PRKIRVNAINPGMIVT 197 >5B1Y-A nrPDB Length = 270 Score = 79.3 bits (194), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 66/219 (30%), Positives = 104/219 (47%), Gaps = 32/219 (14%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQ----- 56 H+ ALVTG ++GIGRA +G W++ + +A L E+ + Sbjct: 20 HMETTYALVTGGSRGIGRATVLRFAREG-------WSVVIAYKSRADLAEKTAEEARRLG 72 Query: 57 --KTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQI 106 + ++ DV D + + +V + L++LVN AGV + WE+TL++ Sbjct: 73 SPEAYTVRVDVGDPDSVTEMSSRVGELIPHLNVLVNAAGVLQLGGIEETSISEWEETLRV 132 Query: 107 NLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMP-VAQQPVYCASKHGIVGFTRSA 165 NL V T L L + K I+N++S+AG V Y ASK G++G T+ Sbjct: 133 NLTGVYLVTKLLLPLLRKAKWAS---IVNVASIAGETGNVVAGVAYSASKAGVIGLTKR- 188 Query: 166 ALAANLMNSGVRLNAICPGFVNT----AILESIEKEENM 200 LA L G+R+NA+ P FV T + L++ EK E + Sbjct: 189 -LAVQLAGYGIRVNAVAPSFVETDMTRSFLDTPEKRERI 226 >3RKU-A nrPDB Length = 287 Score = 78.6 bits (192), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 58/195 (29%), Positives = 94/195 (48%), Gaps = 17/195 (8%) Query: 6 KVALVTGAAQGIGRAFAEALLLKG---AKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 K L+TGA+ GIG+A A L K+ L LE + K +D++F K Q Sbjct: 34 KTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPNAKVHVAQ 93 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAG--VNNEK-------NWEKTLQINLVSVIS 113 D+ ++++ + F +DILVNNAG + +++ + + N+ ++I+ Sbjct: 94 LDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQIATEDIQDVFDTNVTALIN 153 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 T L +N G+ I+N+ S+AG +YCASK + FT S L L+N Sbjct: 154 ITQAVLPIFQAKNSGD---IVNLGSIAGRDAYPTGSIYCASKFAVGAFTDS--LRKELIN 208 Query: 174 SGVRLNAICPGFVNT 188 + +R+ I PG V T Sbjct: 209 TKIRVILIAPGLVET 223 >4K6F-A nrPDB Length = 255 Score = 78.2 bits (191), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 61/201 (30%), Positives = 96/201 (47%), Gaps = 16/201 (7%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI-QCD 64 ++A+VTG G+G A + L G +V + G L E + D Sbjct: 12 RIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNTGAD--RWLTEMHAAGREFHAYPVD 69 Query: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEK--------NWEKTLQINLVSVISGTY 116 VAD + K+V G +DILVNNAG+ + NW+ ++ NL SV + T Sbjct: 70 VADHDSCQQCIEKIVRDVGPVDILVNNAGITRDMTLRKLDKVNWDAVIRTNLDSVFNMTK 129 Query: 117 LGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGV 176 D M ++ G I+N+SS+ G Q Y A+K G+ GFT+S LA + GV Sbjct: 130 PVCDGMVERGWGR---IVNISSVNGSKGSVGQTNYAAAKAGMHGFTKS--LALEIARKGV 184 Query: 177 RLNAICPGFVNTAILESIEKE 197 +N + PG++ T ++ +I ++ Sbjct: 185 TVNTVSPGYLATKMVTAIPQD 205 >4KMS-A nrPDB Length = 249 Score = 78.2 bits (191), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 56/201 (27%), Positives = 104/201 (51%), Gaps = 20/201 (9%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 ++A+VTG +GIG+A A L KG V N + ++E++ + + +V Sbjct: 11 EIAIVTGGTRGIGKATALELKNKGLTVVA---NFFSNYDAAKEMEEKYGIKTKCW---NV 64 Query: 66 ADQQQLRDTFRKVVDHFGR-LDILVNNAGVNNEK--------NWEKTLQINLVSVISGTY 116 AD ++ R +++ + F + + ILVNNAG+ +K +W + +NL S + + Sbjct: 65 ADFEECRQAVKEIEEEFKKPVSILVNNAGITKDKMLHRMSHQDWNDVINVNLNSCFNMSS 124 Query: 117 LGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGV 176 ++ M Q+ G I+N+SS+ Q Y A+K GI+GFT+ ALA + + Sbjct: 125 SVMEQMRNQDYGR---IVNISSINAQAGQVGQTNYSAAKAGIIGFTK--ALARETASKNI 179 Query: 177 RLNAICPGFVNTAILESIEKE 197 +N I PG++ T ++ ++ ++ Sbjct: 180 TVNCIAPGYIATEMVGAVPED 200 >3O4R-A nrPDB Length = 261 Score = 77.0 bits (188), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 66/215 (30%), Positives = 96/215 (44%), Gaps = 20/215 (9%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 KVALVT + GIG A A L GA V + + Q A L Q E C V Sbjct: 16 KVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATL--QGEGLSVTGTVCHV 73 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVN---------NEKNWEKTLQINLVSVISGTY 116 + V G +DILV+NA VN E+ W+KTL IN+ + T Sbjct: 74 GKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTK 133 Query: 117 LGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGV 176 + M K+ GG ++ +SS+A P Y SK ++G T++ LA L + Sbjct: 134 AVVPEMEKRGGGS---VVIVSSIAAFSPSPGFSPYNVSKTALLGLTKT--LAIELAPRNI 188 Query: 177 RLNAICPGFVNTAILESI----EKEENMGQYIEYK 207 R+N + PG + T+ + EKEE+M + + + Sbjct: 189 RVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIR 223 >3EZL-A nrPDB Length = 256 Score = 77.0 bits (188), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 62/211 (29%), Positives = 101/211 (47%), Gaps = 26/211 (12%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQF-EPQKTL 59 M ++ ++A VTG GIG + + L G +V AG + ++ E QK L Sbjct: 9 MVMSQRIAYVTGGMGGIGTSICQRLHKDGFRVV-------AGCGPNSPRRVKWLEDQKAL 61 Query: 60 FI-----QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQI 106 + +V D + F KV G +D+LVNNAG+ + ++W+ + Sbjct: 62 GFDFYASEGNVGDWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTREDWQAVIDT 121 Query: 107 NLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAA 166 NL S+ + T +D M ++ G IIN+SS+ G Q Y +K GI GFT S Sbjct: 122 NLTSLFNVTKQVIDGMVERGWGR---IINISSVNGQKGQFGQTNYSTAKAGIHGFTMS-- 176 Query: 167 LAANLMNSGVRLNAICPGFVNTAILESIEKE 197 LA + GV +N + PG++ T ++++I + Sbjct: 177 LAQEVATKGVTVNTVSPGYIGTDMVKAIRPD 207 >1GEE-A nrPDB Length = 261 Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 55/197 (27%), Positives = 100/197 (50%), Gaps = 15/197 (7%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDE-QFEPQKTLFI 61 + GKV ++TG++ G+G++ A + AKV +V++ + + + L+E + + + + Sbjct: 5 LEGKVVVITGSSTGLGKSMAIRFATEKAKV-VVNYRSKED-EANSVLEEIKKVGGEAIAV 62 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVIS 113 + DV + + + + + FG+LD+++NNAG+ N +W K + NL Sbjct: 63 KGDVTVESDVINLVQSAIKEFGKLDVMINNAGLENPVSSHEMSLSDWNKVIDTNLTGAFL 122 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 G+ + Y + + G +INMSS+ +P Y ASK G+ T + LA Sbjct: 123 GSREAIKYFVEND--IKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTET--LALEYAP 178 Query: 174 SGVRLNAICPGFVNTAI 190 G+R+N I PG +NT I Sbjct: 179 KGIRVNNIGPGAINTPI 195 >2HSD-A nrPDB Length = 253 Score = 75.5 bits (184), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 62/209 (29%), Positives = 96/209 (45%), Gaps = 18/209 (8%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 ++GK ++TG A+G+G A + GA+V L D E G L + Q Sbjct: 3 LSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQ-----H 57 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVISG 114 DV ++ + + FG +D LVNNAG++ + + K ++INL V G Sbjct: 58 LDVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVEINLTGVFIG 117 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 + M GG I+N+SS AGLM +A Y ASK G+ G ++ AA+ L Sbjct: 118 MKTVIPAMKDAGGGS---IVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAV--ELGTD 172 Query: 175 GVRLNAICPGFVNTAILESIEKEENMGQY 203 +R+N++ PG T + + G Y Sbjct: 173 RIRVNSVHPGMTYTPMTAETGIRQGEGNY 201 >4HP8-A nrPDB Length = 247 Score = 74.3 bits (181), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 64/224 (28%), Positives = 101/224 (45%), Gaps = 45/224 (20%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + G+ ALVTGA G+G+A A L GA+V C A + P +TL Sbjct: 5 FSLEGRKALVTGANTGLGQAIAVGLAAAGAEVV-----------CAA----RRAPDETLD 49 Query: 61 IQC-----------DVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWE 101 I D AD +D+F DILVNNAG+ +E +W+ Sbjct: 50 IIAKDGGNASALLIDFADPLAAKDSFTDA-----GFDILVNNAGIIRRADSVEFSELDWD 104 Query: 102 KTLQINLVSVISGT-YLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVG 160 + + +NL ++ T + ++K G G ++N++SL + P Y A+KHG+ G Sbjct: 105 EVMDVNLKALFFTTQAFAKELLAK---GRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAG 161 Query: 161 FTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYI 204 T+ LA G+ +NAI PG++ T E++ + + I Sbjct: 162 LTK--LLANEWAAKGINVNAIAPGYIETNNTEALRADAARNKAI 203 >3ZV3-A nrPDB Length = 281 Score = 74.3 bits (181), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 53/201 (26%), Positives = 93/201 (46%), Gaps = 25/201 (12%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M + G+VAL+TG A G+GRA + + +GA+VA++D + E + + A + Sbjct: 1 MKLTGEVALITGGASGLGRALVDRFVAEGARVAVLDKSAERLRELEVA-----HGGNAVG 55 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN-------------EKNWEKTLQIN 107 + DV Q + + + FG++D L+ NAG+ + + ++ +N Sbjct: 56 VVGDVRSLQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDIFHVN 115 Query: 108 LVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 + I L + G ++ +S+ AG P P+Y A+KH +VG R A Sbjct: 116 VKGYIHAVKACLPALVSS---RGSVVFTISN-AGFYPNGGGPLYTATKHAVVGLVRQMAF 171 Query: 168 AANLMNSGVRLNAICPGFVNT 188 + VR+N + PG +NT Sbjct: 172 E---LAPHVRVNGVAPGGMNT 189 >2B4Q-A nrPDB Length = 276 Score = 74.3 bits (181), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 60/203 (29%), Positives = 96/203 (47%), Gaps = 15/203 (7%) Query: 5 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64 G++ALVTG ++GIG+ A+ LL GA+V + + EA L + Q I D Sbjct: 29 GRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYGDCQA---IPAD 85 Query: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISGTY 116 ++ + R + + + RLDILVNNAG + WEK +Q+N+ SV S Sbjct: 86 LSSEAGARRLAQALGELSARLDILVNNAGTSWGAALESYPVSGWEKVMQLNVTSVFSCIQ 145 Query: 117 LGLDYMSKQNGGEG-GIIINMSSLAGLMPVAQQP-VYCASKHGIVGFTRSAALAANLMNS 174 L + + E +IN+ S+AG+ + +Q Y SK + +R LA L+ Sbjct: 146 QLLPLLRRSASAENPARVINIGSVAGISAMGEQAYAYGPSKAALHQLSR--MLAKELVGE 203 Query: 175 GVRLNAICPGFVNTAILESIEKE 197 + +N I PG + + I + Sbjct: 204 HINVNVIAPGRFPSRMTRHIAND 226 >2FWM-X nrPDB Length = 250 Score = 73.9 bits (180), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 74/248 (29%), Positives = 112/248 (45%), Gaps = 33/248 (13%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M +GK VTGA +GIG A A A + GAKV D +A EQ+ P T Sbjct: 3 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD---------QAFTQEQY-PFATEV 52 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVI 112 + DVAD Q+ ++++ RLD LVN AG+ ++++W++T +N+ Sbjct: 53 M--DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAF 110 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + ++ +Q GG I+ ++S A P Y ASK + S L L Sbjct: 111 NLFQQTMNQFRRQRGGA---IVTVASDAAHTPRIGMSAYGASKAALKSLALSVGL--ELA 165 Query: 173 NSGVRLNAICPGFVNTAILESI----EKEENMGQYIE-YKDHIKDMIKYYGILDPPLIAN 227 SGVR N + PG +T + ++ + EE Q I + + K I I P IAN Sbjct: 166 GSGVRCNVVSPGSTDTDMQRTLWVSDDAEE---QRIRGFGEQFKLGIPLGKIARPQEIAN 222 Query: 228 GLITLIED 235 ++ L D Sbjct: 223 TILFLASD 230 >1MG5-A nrPDB Length = 255 Score = 73.2 bits (178), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 39/132 (29%), Positives = 69/132 (52%), Gaps = 5/132 (3%) Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLD 120 + +A+ +L + + +D+L+N AG+ ++ E+T+ +N +++ T LD Sbjct: 65 VTVPIAETTKL---LKTIFAQLKTVDVLINGAGILDDHQIERTIAVNYTGLVNTTTAILD 121 Query: 121 YMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNA 180 + K+ GG GGII N+ S+ G + Q PVY +K +V FT S A A + +GV Sbjct: 122 FWDKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAKLAPI--TGVTAYT 179 Query: 181 ICPGFVNTAILE 192 + PG T ++ Sbjct: 180 VNPGITRTTLVH 191 >1AE1-A nrPDB Length = 273 Score = 73.2 bits (178), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 67/207 (32%), Positives = 97/207 (46%), Gaps = 22/207 (10%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFE--PQKTLF 60 + G ALVTG ++GIG A E L GA+V N + LDE E +K L Sbjct: 19 LKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRN-------EKELDECLEIWREKGLN 71 Query: 61 IQCDVAD--QQQLRDTFRKVVDHF--GRLDILVNNAGVNNEKNWEKTLQINLVSVISGTY 116 ++ V D + RD + V H G+L+ILVNNAGV K K ++I GT Sbjct: 72 VEGSVCDLLSRTERDKLMQTVAHVFDGKLNILVNNAGVVIHKE-AKDFTEKDYNIIMGTN 130 Query: 117 LGLDYMSKQ------NGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAAN 170 Y Q + G +I +SS+AG + +Y ASK I T+S LA Sbjct: 131 FEAAYHLSQIAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKS--LACE 188 Query: 171 LMNSGVRLNAICPGFVNTAILESIEKE 197 +R+N++ PG + T ++E+ K+ Sbjct: 189 WAKDNIRVNSVAPGVILTPLVETAIKK 215 >3UF0-A nrPDB Length = 273 Score = 72.8 bits (177), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 64/214 (29%), Positives = 100/214 (46%), Gaps = 23/214 (10%) Query: 5 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTL-FIQC 63 G+ A+VTGA GIGRA A GA V + W GV K DE + + + Sbjct: 31 GRTAVVTGAGSGIGRAIAHGYARAGAHV--LAWGRTDGV--KEVADEIADGGGSAEAVVA 86 Query: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEK--------NWEKTLQINL--VSVIS 113 D+AD + + ++ R+D+LVNNAG+ W + L +NL V+S Sbjct: 87 DLADLEGAANVAEELAATR-RVDVLVNNAGIIARAPAEEVSLGRWREVLTVNLDAAWVLS 145 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 ++ G ++ + G I+ ++S+ Y ASKH +VG TR ALA+ Sbjct: 146 RSF-GTAMLAHGS----GRIVTIASMLSFQGGRNVAAYAASKHAVVGLTR--ALASEWAG 198 Query: 174 SGVRLNAICPGFVNTAILESIEKEENMGQYIEYK 207 GV +NA+ PG+V TA ++ ++ I + Sbjct: 199 RGVGVNALAPGYVVTANTAALRADDERAAEITAR 232 >1BDB-A nrPDB Length = 277 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 56/201 (27%), Positives = 91/201 (45%), Gaps = 25/201 (12%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M + G+ L+TG A G+GRA + + +GAKVA++D + E + A E L Sbjct: 1 MKLKGEAVLITGGASGLGRALVDRFVAEGAKVAVLDKSAE-----RLAELETDHGDNVLG 55 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN-------------EKNWEKTLQIN 107 I DV + + + V FG++D L+ NAG+ + + +++ IN Sbjct: 56 IVGDVRSLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHIN 115 Query: 108 LVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 + I L + G +I +S+ AG P P+Y A+KH IVG R A Sbjct: 116 VKGYIHAVKACLPALVAS---RGNVIFTISN-AGFYPNGGGPLYTAAKHAIVGLVRELAF 171 Query: 168 AANLMNSGVRLNAICPGFVNT 188 + VR+N + G +N+ Sbjct: 172 E---LAPYVRVNGVGSGGINS 189 >5VT6-A nrPDB Length = 269 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 54/200 (27%), Positives = 98/200 (49%), Gaps = 14/200 (7%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 +VA VTG G+G A + L G VA+ V + E+ + DV Sbjct: 26 RVAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWL-MHERDAGRDFKAYAVDV 84 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEK--------NWEKTLQINLVSVISGTYL 117 AD + KV+ FG++D+L+NNAG+ + +W+ ++ +L ++ + T Sbjct: 85 ADFESCERCAEKVLADFGKVDVLINNAGITRDATFMKMTKGDWDAVMRTDLDAMFNVTKQ 144 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 + M ++ G I+N+ S+ G Q Y ++K GI GFT++ LA G+ Sbjct: 145 FIAGMVERRFGR---IVNIGSVNGSRGAFGQANYASAKAGIHGFTKT--LALETAKRGIT 199 Query: 178 LNAICPGFVNTAILESIEKE 197 +N + PG++ TA++E++ ++ Sbjct: 200 VNTVSPGYLATAMVEAVPQD 219 >3A28-C nrPDB Length = 258 Score = 72.0 bits (175), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 61/200 (30%), Positives = 93/200 (46%), Gaps = 12/200 (6%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 KVA+VTG AQGIGR +E L G +A+ D + + + QK +F+ DV Sbjct: 3 KVAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQEEQAAETIKLIEAADQKAVFVGLDV 62 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNN-----EKNWEKTLQINLVSVISGTYLGLD 120 D+ + + G D+LVNNAG+ E E QI V+V S + G+ Sbjct: 63 TDKANFDSAIDEAAEKLGGFDVLVNNAGIAQIKPLLEVTEEDLKQIYSVNVFS-VFFGIQ 121 Query: 121 YMSKQNGGEGGIIINMSSLAGLMPVAQQPV---YCASKHGIVGFTRSAALAANLMNSGVR 177 S++ E G+ + + A + + P+ Y +K + G T++A A L G Sbjct: 122 AASRKF-DELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAA--AQELAPKGHT 178 Query: 178 LNAICPGFVNTAILESIEKE 197 +NA PG V T + E I+ E Sbjct: 179 VNAYAPGIVGTGMWEQIDAE 198 >4RZI-B nrPDB Length = 240 Score = 72.0 bits (175), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 58/212 (27%), Positives = 99/212 (46%), Gaps = 27/212 (12%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 KV +VTG +GIG A + L GAKVA D + G + L + +V Sbjct: 9 KVIVVTGGNRGIGAAIVKLLQEMGAKVAFTDLATDGG------------NTEALGVVANV 56 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEK--------NWEKTLQINLVSVISGTYL 117 D + + ++ D G + +V NAG+ + +W+ L +NL V Sbjct: 57 TDLESMTAAAAEITDKLGPVYGVVANAGITKDNFFPKLTPADWDAVLNVNLKGVAYSIKP 116 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 ++ M ++ G I+ +SS++G Q Y A+K G++G +S LA GVR Sbjct: 117 FIEGMYERKAGS---IVAISSISGERGNVGQTNYSATKAGVIGMMKS--LAREGARYGVR 171 Query: 178 LNAICPGFVNTAILESIEKE--ENMGQYIEYK 207 NA+ PGF++T + +I ++ E + + I ++ Sbjct: 172 ANAVAPGFIDTEMTLAIREDIREKITKEIPFR 203 >2AG5-A nrPDB Length = 246 Score = 72.0 bits (175), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 72/205 (35%), Positives = 109/205 (53%), Gaps = 35/205 (17%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 ++GKV ++T AAQGIG+A A A +GAKV D N E+ +Q E +K I Sbjct: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDIN-ESKLQ---------ELEKYPGI 52 Query: 62 QCDVADQQQLRDTFRKVVDHFG----RLDILVNNAGV--------NNEKNWEKTLQINLV 109 Q V D T +K +D F RLD+L N AG EK+W+ ++ +N+ Sbjct: 53 QTRVLDV-----TKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVR 107 Query: 110 SVISGTYLGLD-YMSKQNGGEGGIIINMSSLAGLMP-VAQQPVYCASKHGIVGFTRSAAL 167 S+ YL + ++ K + G IINMSS+A + V + VY +K ++G T+S + Sbjct: 108 SM----YLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKS--V 161 Query: 168 AANLMNSGVRLNAICPGFVNTAILE 192 AA+ + G+R N +CPG V+T L+ Sbjct: 162 AADFIQQGIRCNCVCPGTVDTPSLQ 186 >2AE2-A nrPDB Length = 260 Score = 71.6 bits (174), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 59/218 (27%), Positives = 107/218 (49%), Gaps = 22/218 (10%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQ-FEPQKTLF 60 ++ G ALVTG ++GIG E L GA V N + C + F+ + ++ Sbjct: 6 NLEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKVEASV- 64 Query: 61 IQCDVADQQQLRDTFRKVVDHF-GRLDILVNNAGVNNEK--------NWEKTLQINLVSV 111 CD++ + + ++ V +HF G+L+ILVNNAG+ K ++ + IN + Sbjct: 65 --CDLSSRSERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINFEAA 122 Query: 112 ISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANL 171 + L ++ E G ++ +SS++G + V + VY A+K + TR LA Sbjct: 123 YHLSVLAHPFL---KASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTR--CLAFEW 177 Query: 172 MNSGVRLNAICPGFVNTAILESI----EKEENMGQYIE 205 +R+N + PG + T+++E E++EN+ + I+ Sbjct: 178 AKDNIRVNGVGPGVIATSLVEMTIQDPEQKENLNKLID 215 >5U9P-A nrPDB Length = 265 Score = 71.2 bits (173), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 54/213 (25%), Positives = 95/213 (44%), Gaps = 17/213 (7%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLE-AGVQCKAALDEQFEPQKTL 59 ++G+ AL+TG+ +GIG A L GA + + D N E A + DE F + Sbjct: 16 FRLDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARRFRDEGFAADHAV 75 Query: 60 FIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSV 111 F DVA+ Q+R + G +DILVNNAG+ +W +++NL V Sbjct: 76 F---DVAEHAQVRAAIDEFEARVGAIDILVNNAGIQRRAPLDAFEPDDWHALMRVNLDGV 132 Query: 112 ISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANL 171 + +M + G+ IIN+ S+ + Y A+K + T+ + A+ Sbjct: 133 FNVAQAVARHMIARGHGK---IINICSVQSELARPTIAPYAATKGAVRMLTKG--MCADW 187 Query: 172 MNSGVRLNAICPGFVNTAILESIEKEENMGQYI 204 G++ N + PG+ T + ++ + ++ Sbjct: 188 ARYGIQANGLAPGYFETELNRALVDDAAFSDWL 220 >3OIC-A nrPDB Length = 258 Score = 71.2 bits (173), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 61/233 (26%), Positives = 108/233 (46%), Gaps = 33/233 (14%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQK----TLFI 61 K ALVTG+++G+G+A A L G + + KAAL+ E +K L + Sbjct: 5 KCALVTGSSRGVGKAAAIRLAENGYNIVI-----NYARSKKAALETAEEIEKLGVKVLVV 59 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVIS 113 + +V ++++ F+++ + FGRLD+ VNNA E +W+ T+ IN +++ Sbjct: 60 KANVGQPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELEETHWDWTMNINAKALLF 119 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 M K GG I+++SSL + + SK + TR LA L Sbjct: 120 CAQEAAKLMEKNGGGH---IVSISSLGSIRYLENYTTVGVSKAALEALTRY--LAVELSP 174 Query: 174 SGVRLNAICPGFVNTAILESIEKEENM----------GQYIEYKDHIKDMIKY 216 + +NA+ G ++T L+ E++ G+ +E KD + D +++ Sbjct: 175 KQIIVNAVSGGAIDTDALKHFPNREDLLEDARQNTPAGRMVEIKDMV-DTVEF 226 >3OML-A nrPDB Length = 613 Score = 71.2 bits (173), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 65/206 (31%), Positives = 94/206 (45%), Gaps = 31/206 (15%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDW---NLEAGVQCKAA---LDEQFE 54 + +G+VA+VTGA G+GR +A +GAKV + D + G +AA +DE + Sbjct: 15 LRYDGRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRK 74 Query: 55 PQKTLFIQCDVADQQQLRD---TFRKVVDHFGRLDILVNNAGV--------NNEKNWEKT 103 VAD + D + FGR+DILVNNAG+ +E++W Sbjct: 75 AGGEA-----VADYNSVIDGAKVIETAIKAFGRVDILVNNAGILRDRSLVKTSEQDWNLV 129 Query: 104 LQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTR 163 ++L T YM KQN G II SS +G+ Q Y A+K G++G Sbjct: 130 NDVHLKGSFKCTQAAFPYMKKQNYGR---IIMTSSNSGIYGNFGQVNYTAAKMGLIGLAN 186 Query: 164 SAALAANLMNSGVRLNAICPGFVNTA 189 + A+ G R N +C V TA Sbjct: 187 TVAI------EGARNNVLCNVIVPTA 206 >2ZAT-A nrPDB Length = 260 Score = 70.9 bits (172), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 60/217 (27%), Positives = 96/217 (44%), Gaps = 16/217 (7%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 KVALVT + GIG A A L GA V + E + A L Q E C V Sbjct: 15 KVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATL--QGEGLSVTGTVCHV 72 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVN---------NEKNWEKTLQINLVSVISGTY 116 + V+ G +DILV+NA VN E+ W+K L +N+ + + T Sbjct: 73 GKAEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKATVLMTK 132 Query: 117 LGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGV 176 + M K+ GG ++ +SS+ P Y SK ++G T++ LA L + Sbjct: 133 AVVPEMEKRGGGS---VLIVSSVGAYHPFPNLGPYNVSKTALLGLTKN--LAVELAPRNI 187 Query: 177 RLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDM 213 R+N + PG + T + + ++ +Y++ I+ + Sbjct: 188 RVNCLAPGLIKTNFSQVLWMDKARKEYMKESLRIRRL 224 >3U5T-A nrPDB Length = 267 Score = 70.9 bits (172), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 74/255 (29%), Positives = 116/255 (45%), Gaps = 28/255 (10%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M N KVA+VTGA++GIG A A L G V ++++ +A + A + K L Sbjct: 24 METN-KVAIVTGASRGIGAAIAARLASDGFTV-VINYAGKAAAAEEVAGKIEAAGGKALT 81 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVI 112 Q DV+D +R F + FG +D+LVNNAG+ + +++ + +NL Sbjct: 82 AQADVSDPAAVRRLFATAEEAFGGVDVLVNNAGIMPLTTIAETGDAVFDRVIAVNL---- 137 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMS-SLAGLMPVAQQPVYCASKHGIVGFTRSAALAANL 171 GT+ L + Q GG IINMS S GL+ +Y A+K G+ T L+ L Sbjct: 138 KGTFNTLRE-AAQRLRVGGRIINMSTSQVGLLH-PSYGIYAAAKAGVEAMTH--VLSKEL 193 Query: 172 MNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLIT 231 + +NA+ PG T + G+ E +D + + P IA + Sbjct: 194 RGRDITVNAVAPGPTATDLFLE-------GKSDEVRDRFAKLAPLERLGTPQDIAGAVAF 246 Query: 232 LIEDDA--LNGAIMK 244 L D +NG +++ Sbjct: 247 LAGPDGAWVNGQVLR 261 >4IIV-A nrPDB Length = 267 Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 60/201 (29%), Positives = 95/201 (47%), Gaps = 17/201 (8%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQ--CKAALDEQFEPQKTLFIQC 63 + LVTGA++GIGRA A L G + + AG Q A + + F Sbjct: 27 RSVLVTGASKGIGRAIARQLAADGFNIGVHYHRDAAGAQETLNAIVANGGNGRLLSF--- 83 Query: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEK--------NWEKTLQINLVSVISGT 115 DVA+++Q R+ + G +V+NAG+ + +W+ + NL S + Sbjct: 84 DVANREQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPALSNDDWDAVIHTNLDSFYN-- 141 Query: 116 YLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSG 175 + M +GG II +SS++G+M Q Y A+K GI+G T+ ALA L Sbjct: 142 VIQPCIMPMIGARQGGRIITLSSVSGVMGNRGQVNYSAAKAGIIGATK--ALAIELAKRK 199 Query: 176 VRLNAICPGFVNTAILESIEK 196 + +N I PG ++T ++E E Sbjct: 200 ITVNCIAPGLIDTGMIEMEES 220 >5T5Q-A nrPDB Length = 247 Score = 68.6 bits (166), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 58/208 (27%), Positives = 91/208 (43%), Gaps = 22/208 (10%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 + ++TGA GIGRA AE GA + L D + E A+L P++ I+ D Sbjct: 10 RTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGS---PERIATIKADA 66 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEK--------NWEKTLQINLVSVISGTYL 117 + T ++ FG +D LV +AG+ K +W +T+ INL V Sbjct: 67 SSADDAEKTVALAMERFGGIDFLVPSAGIYQAKPFAEMSDADWHRTISINLDGVFYLCKR 126 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 L + + + I+ ++SLA Y A+K +V TR AL+ L R Sbjct: 127 ALPALKEDSS-----IVTLASLAAYRGAYVNAHYGATKGAMVSMTR--ALSRELAPK-TR 178 Query: 178 LNAICPGFVNTAILESIEK---EENMGQ 202 +N + PG + T + + K +E M Q Sbjct: 179 VNGVSPGIIETPMTSELLKTRMDETMTQ 206 >4EGF-A nrPDB Length = 266 Score = 68.6 bits (166), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 66/214 (30%), Positives = 107/214 (50%), Gaps = 29/214 (13%) Query: 1 MHVNGKVALVTGAAQGIG-------RAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQF 53 + ++GK AL+TGA +GIG A L+L G V+ +D + AL EQF Sbjct: 16 LRLDGKRALITGATKGIGADIARAFAAAGARLVLSGRDVSELD-------AARRALGEQF 68 Query: 54 EPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKN--------WEKTLQ 105 + D+A+ + R+ + FG LD+LVNNAG+++ + ++ T+ Sbjct: 69 G-TDVHTVAIDLAEPDAPAELARRAAEAFGGLDVLVNNAGISHPQPVVDTDPQLFDATIA 127 Query: 106 INL-VSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRS 164 +NL + + +G ++ GEGG II ++S A L P+ YC SK G+V T+ Sbjct: 128 VNLRAPALLASAVGKAMVAA---GEGGAIITVASAAALAPLPDHYAYCTSKAGLVMATK- 183 Query: 165 AALAANLMNSGVRLNAICPGFVNTAILESIEKEE 198 LA L G+R N++CP V T + + + +E Sbjct: 184 -VLARELGPHGIRANSVCPTVVLTEMGQRVWGDE 216 >1AHH-A nrPDB Length = 255 Score = 68.2 bits (165), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 63/218 (28%), Positives = 104/218 (47%), Gaps = 19/218 (8%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDE-QFEPQKTL 59 + ++GK A++TGA GIG+ A GA V + D N +A +DE Q + Sbjct: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADA---ANHVVDEIQQLGGQAF 63 Query: 60 FIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEK-------NWEKTLQINLVSVI 112 +CD+ +Q+L + G++DILVNNAG K ++ + ++N+ S Sbjct: 64 ACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFF 123 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + L M K NG GG+I+ ++S+A Y +SK R+ +A +L Sbjct: 124 HLSQLVAPEMEK-NG--GGVILTITSMAAENKNINMTSYASSKAAASHLVRN--MAFDLG 178 Query: 173 NSGVRLNAICPGFVNTAILESI---EKEENMGQYIEYK 207 +R+N I PG + T L+S+ E E+ M Q+ + Sbjct: 179 EKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIR 216 >3R3S-A nrPDB Length = 294 Score = 67.8 bits (164), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 57/196 (29%), Positives = 91/196 (46%), Gaps = 20/196 (10%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVAL--VDWNLEAGVQCKAALDEQFEPQKTLFIQC 63 + ALVTG GIGRA A A +GA VA+ + E Q KA ++E +K + + Sbjct: 50 RKALVTGGDSGIGRAAAIAYAREGADVAINYLPAEEEDAQQVKALIEECG--RKAVLLPG 107 Query: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVN---------NEKNWEKTLQINLVSVISG 114 D++D+ R K + G LDIL AG + +++T +N+ ++ Sbjct: 108 DLSDESFARSLVHKAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQTFAVNVFALFWI 167 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 T + + K G II SS+ P Y A+K I+ ++R LA + Sbjct: 168 TQEAIPLLPK-----GASIITTSSIQAYQPSPHLLDYAATKAAILNYSR--GLAKQVAEK 220 Query: 175 GVRLNAICPGFVNTAI 190 G+R+N + PG + TA+ Sbjct: 221 GIRVNIVAPGPIWTAL 236 >4GKB-A nrPDB Length = 258 Score = 67.0 bits (162), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 46/146 (31%), Positives = 72/146 (49%), Gaps = 14/146 (9%) Query: 52 QFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN-------EKNWEKTL 104 Q +P+ T ++ ++ D Q RD + + FGRLD LVNNAGVN+ + +L Sbjct: 52 QRQPRAT-YLPVELQDDAQCRDAVAQTIATFGRLDGLVNNAGVNDGIGLDAGRDAFVASL 110 Query: 105 QINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRS 164 + NL+ + + + ++ G I+N+SS + YCASK + TR Sbjct: 111 ERNLIHYYAMAHYCVPHLKATRGA----IVNISSKTAVTGQGNTSGYCASKGAQLALTRE 166 Query: 165 AALAANLMNSGVRLNAICPGFVNTAI 190 A+A L GVR+NA+ P V T + Sbjct: 167 WAVA--LREHGVRVNAVIPAEVMTPL 190 >6CI9-A nrPDB Length = 259 Score = 67.0 bits (162), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 62/221 (28%), Positives = 97/221 (43%), Gaps = 24/221 (10%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 + G+ A+VTG ++GIGR AE G V + N + + D K ++ Sbjct: 7 LEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDD--LDRTVADLSGTRGKVTAVR 64 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYM 122 DV D + R T + V G LDI+ NAG+ E ++ V+ + G Y+ Sbjct: 65 ADVTDPEDARRTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKGTVYI 124 Query: 123 SK------QNGGEGGIIINMSSLAGLMPVAQQPV---YCASKHGIVGFTRSAALAANLMN 173 + G G +++ SS+ G P+ P Y ASK +GF R+AA+ L Sbjct: 125 VQAALQALTASGHGRVVVT-SSITG--PITGYPGWSHYGASKAAQLGFLRTAAM--ELAP 179 Query: 174 SGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMI 214 + +NA+ PG + T E + MGQ +Y D + I Sbjct: 180 KKITINAVLPGNIMT------EGLDEMGQ--DYLDQMASAI 212 >4CR6-A nrPDB Length = 271 Score = 67.0 bits (162), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 58/198 (29%), Positives = 88/198 (44%), Gaps = 21/198 (10%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 + GK A+VTGAA GIGRA EA L +GA V +D ++E + I Sbjct: 12 RLAGKAAIVTGAAGGIGRATVEAYLREGASVVAMDLAPRLAAT-------RYEEPGAIPI 64 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN---------NEKNWEKTLQINLVSVI 112 CD+AD+ + V G LDILV + ++ +W++ + +N+ Sbjct: 65 ACDLADRAAIDAAMADAVARLGGLDILVAGGALKGGTGNFLDLSDADWDRYVDVNMTGTF 124 Query: 113 SGTYLGLDYMSKQNGGEGG---IIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAA 169 G M G+ G II + S+ M + Y A+K G+ TR A+A Sbjct: 125 LTCRAGARAMVAAGAGKDGRSARIITIGSVNSFMAEPEAAAYVAAKGGVAMLTR--AMAV 182 Query: 170 NLMNSGVRLNAICPGFVN 187 +L G+ +N I PG V+ Sbjct: 183 DLARHGILVNMIAPGPVD 200 >3UN1-A nrPDB Length = 260 Score = 66.2 bits (160), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 57/195 (29%), Positives = 88/195 (45%), Gaps = 26/195 (13%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 KV ++TGA+QGIG A + +V ++ K + D + D+ Sbjct: 29 KVVVITGASQGIGAGLVRAYRDRNYRVVATSRSI------KPSADPDIHT-----VAGDI 77 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVISGTYL 117 + + R+ ++ FGR+D LVNNAGV +++++ L +N+ T Sbjct: 78 SKPETADRIVREGIERFGRIDSLVNNAGVFLAKPFVEMTQEDYDHNLGVNVAGFFHITQR 137 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCAS--KHGIVGFTRSAALAANLMNSG 175 M KQ G G I+ +SL P+ P AS K G+ TRS LA SG Sbjct: 138 AAAEMLKQ--GSGHIVSITTSLVD-QPMVGMPSALASLTKGGLNAVTRS--LAMEFSRSG 192 Query: 176 VRLNAICPGFVNTAI 190 VR+NA+ PG + T + Sbjct: 193 VRVNAVSPGVIKTPM 207 >4DA9-A nrPDB Length = 280 Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 41/142 (28%), Positives = 71/142 (50%), Gaps = 12/142 (8%) Query: 57 KTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN----------EKNWEKTLQI 106 + +F++ D+AD + T VV FGR+D LVNNAG+ + +N++ + + Sbjct: 80 RVIFLRADLADLSSHQATVDAVVAEFGRIDCLVNNAGIASIVRDDFLDLKPENFDTIVGV 139 Query: 107 NLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAA 166 NL + T L M + IIN++S++ +M ++ YC SK G+ F S Sbjct: 140 NLRGTVFFTQAVLKAMLASDARASRSIINITSVSAVMTSPERLDYCMSKAGLAAF--SQG 197 Query: 167 LAANLMNSGVRLNAICPGFVNT 188 LA L +G+ + + PG + + Sbjct: 198 LALRLAETGIAVFEVRPGIIRS 219 >4DRY-A nrPDB Length = 281 Score = 64.7 bits (156), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 41/116 (35%), Positives = 50/116 (43%), Gaps = 10/116 (8%) Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN---------NEKNWEKTLQINLVSV 111 + CDV D Q+ F V F RLD+LVNNAG N + W + NL Sbjct: 88 VVCDVGDPDQVAALFAAVRAEFARLDLLVNNAGSNVPPVPLEEVTFEQWNGIVAANLTGA 147 Query: 112 ISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 T M Q GG IIN S++ P Y A+KH I G T+S AL Sbjct: 148 FLCTQHAFRMMKAQT-PRGGRIINNGSISAQTPRPNSAPYTATKHAITGLTKSTAL 202 >6NRP-A nrPDB Length = 263 Score = 64.3 bits (155), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 57/227 (25%), Positives = 112/227 (49%), Gaps = 31/227 (13%) Query: 9 LVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQ 68 LVTG+++GIG+A A L G V + + +A + + + Q Q + ++ DV ++ Sbjct: 28 LVTGSSRGIGKAIALQLAKAGFDVTVHARSRQAEAE-QVVQEIQALGQNSHYLMFDVNER 86 Query: 69 QQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINL---VSVISGTYL 117 Q ++ + V+ G +V NAG+ ++ ++W++ + +L +V+ + Sbjct: 87 QTVQQILEQDVEQHGGFYGVVLNAGLTHDGAFPALTDQDWDEVISTSLDGFYNVLKPLIM 146 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 + ++ K GG I+ +SS++G+M Q Y A+K G++G T+ ALA L + Sbjct: 147 PMIHLRK-----GGRIVTLSSVSGIMGNRGQVNYSAAKAGLIGATK--ALALELAKRKIT 199 Query: 178 LNAICPGFVNTAILESIEKE--------ENMGQYIEYKDHIKDMIKY 216 +N + PG + T ++ KE + MGQ D + ++K+ Sbjct: 200 VNCVAPGLIETEMVTDEVKEHALKMIPLQRMGQV----DEVASVVKF 242 >2X9N-A nrPDB Length = 288 Score = 63.9 bits (154), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 60/210 (28%), Positives = 95/210 (45%), Gaps = 31/210 (14%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWN-LEAGVQCKAALDEQFEPQKTLF 60 H+ A+VTGAA+ IGRA A L G +V + N EA V L+++ + Sbjct: 20 HMEAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKE-RSNTAVV 78 Query: 61 IQCDVADQQQLRDTFRKVVDH----FGRLDILVNNA----------GVNNEKNWEKTLQI 106 Q D+ + L + ++++ FGR D+LVNNA G + + + KT++ Sbjct: 79 CQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDNSNGKTVET 138 Query: 107 NLVSVISGT------YLGLDYMSKQNGGEGGI------IINMSSLAGLMPVAQQPVYCAS 154 + +I GT L + + +Q G I+N+ P +Y Sbjct: 139 QVAELI-GTNAIAPFLLTMSFAQRQKGTNPNCTSSNLSIVNLCDAMVDQPCMAFSLYNMG 197 Query: 155 KHGIVGFTRSAALAANLMNSGVRLNAICPG 184 KH +VG T+SAAL L G+R+N + PG Sbjct: 198 KHALVGLTQSAAL--ELAPYGIRVNGVAPG 225 >1DOH-A nrPDB Length = 283 Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 55/201 (27%), Positives = 100/201 (49%), Gaps = 11/201 (5%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDW--NLEAGVQCKAALDEQFEPQKTLF 60 + GKVALVTGA +GIGR A L +G KV +V++ + E+ + AA+ + Sbjct: 27 LEGKVALVTGAGRGIGREMAMELGRRGCKV-IVNYANSTESAEEVVAAIKKN--GSDAAC 83 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLD 120 ++ +V + + F + V FG+LDI+ +N+GV + + + V + G Sbjct: 84 VKANVGVVEDIVRMFEEAVKIFGKLDIVCSNSGVVSFGHVKDVTPEEFDRVFTINTRGQF 143 Query: 121 YMSKQNGGE---GGIIINMSSLAG-LMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGV 176 +++++ GG +I M S+ G V + VY SK I F R +A ++ + + Sbjct: 144 FVAREAYKHLEIGGRLILMGSITGQAKAVPKHAVYSGSKGAIETFAR--CMAIDMADKKI 201 Query: 177 RLNAICPGFVNTAILESIEKE 197 +N + PG + T + ++ +E Sbjct: 202 TVNVVAPGGIKTDMYHAVCRE 222 >5JY1-A nrPDB Length = 274 Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 62/196 (31%), Positives = 92/196 (46%), Gaps = 16/196 (8%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 +VALVTGA GIGR A + +GA V + + N G Q + + E ++LF++ DV Sbjct: 15 RVALVTGAGGGIGRGVARSFGNEGAAVIIAEINESTGRQVEQEIREM--GGRSLFVKTDV 72 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNN-----EKNWEKTLQINLVSVISGTYLGLD 120 + + R V+ FG LDILVNNA V E+ ++ L+ L + + T+ + Sbjct: 73 TSKASIEAAVRSAVEQFGSLDILVNNAFVPTPNVLLEEKTDEMLEQTLTTSLWATWWAMR 132 Query: 121 Y----MSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGV 176 M ++ G I+N S+ Y +K GIVG TRSAA N + Sbjct: 133 AAFVPMRERRWGR---IVNFYSIDTETGAWLHGDYNTAKAGIVGLTRSAASEWGRFN--I 187 Query: 177 RLNAICPGFVNTAILE 192 +NAI P + E Sbjct: 188 TVNAIAPTAMGATFFE 203 >3PXX-A nrPDB Length = 287 Score = 62.0 bits (149), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 61/219 (27%), Positives = 92/219 (42%), Gaps = 34/219 (15%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVD---------WNLEAGVQC-KAALDE 51 V KV LVTG A+G GR+ A L +GA + L D + L +A L+ Sbjct: 7 RVQDKVVLVTGGARGQGRSHAVKLAEEGADIILFDICHDIETNEYPLATSRDLEEAGLEV 66 Query: 52 QFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN------NEKNWEKTLQ 105 + +K + DV D+ + V FG+LD++V NAG+ + + Sbjct: 67 EKTGRKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANAGICPLGAHLPVQAFADAFD 126 Query: 106 INLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLM-----------PVAQQPVYCAS 154 ++ V VI+ + L Y++ G II S+AGL+ Y + Sbjct: 127 VDFVGVINTVHAALPYLTS-----GASIITTGSVAGLIAAAQPPGAGGPQGPGGAGYSYA 181 Query: 155 KHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILES 193 K + +T LAA L +R N I P VNT +L S Sbjct: 182 KQLVDSYTLQ--LAAQLAPQSIRANVIHPTNVNTDMLNS 218 >5O3Z-A nrPDB Length = 263 Score = 62.0 bits (149), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 62/229 (27%), Positives = 104/229 (45%), Gaps = 20/229 (8%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 +VA+V G Q +G E L G VA+ D N + ++ ++ + + D Sbjct: 7 QVAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTINSRYGAGRAYGFKVDA 66 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVISGTYL 117 D+ + R V + FGR D+LV +AGV +++ +LQ+NLV G +L Sbjct: 67 TDEASVEALARAVDETFGRADLLVYSAGVAKAAPITQFRLTDFDLSLQVNLV----GYFL 122 Query: 118 GLDYMSKQ--NGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSG 175 SK G G II ++S +G + Y A+K G VG T+S LA +L G Sbjct: 123 CSREFSKLMIRDGIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQS--LALDLAEYG 180 Query: 176 VRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPL 224 + ++++ G +L+S + + QY E + ++ Y + PL Sbjct: 181 ITVHSLMLG----NLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPL 225 >3PPI-A nrPDB Length = 281 Score = 61.2 bits (147), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 70/261 (26%), Positives = 113/261 (43%), Gaps = 38/261 (14%) Query: 5 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64 G A+V+G A G+G A L G V + D E G KA DE + F+ + Sbjct: 30 GASAIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKG---KALADEL--GNRAEFVSTN 84 Query: 65 VADQ----------QQLRDTFRKVVDH--FGRLDILVNNAGVNNE-KNWEKTLQINLVSV 111 V + QL VV H FG +V G + + KT+ + L Sbjct: 85 VTSEDSVLAAIEAANQLGRLRYAVVAHGGFGVAQRIVQRDGSPADMGGFTKTIDLYL--- 141 Query: 112 ISGTY-------LGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRS 164 +GTY + + GE G ++ +S+AG Q Y A+K G++G T + Sbjct: 142 -NGTYNVARLVAASIAAAEPRENGERGALVLTASIAGYEGQIGQTAYAAAKAGVIGLTIA 200 Query: 165 AALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPL 224 AA +L ++G+R+N I PG + T I+ES+ EE + ++ K + P Sbjct: 201 AAR--DLSSAGIRVNTIAPGTMKTPIMESV-GEEALAKFAANIPFPKRLGT------PDE 251 Query: 225 IANGLITLIEDDALNGAIMKI 245 A+ L+ + +NG +M++ Sbjct: 252 FADAAAFLLTNGYINGEVMRL 272 >4HBG-A nrPDB Length = 286 Score = 61.2 bits (147), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 71/281 (25%), Positives = 120/281 (42%), Gaps = 59/281 (20%) Query: 7 VALVTGAAQGIGRAFAEALLLKG-------------AKVALVDWNLEAGV----QCKAAL 49 VA+VTGA +GIG+A + L KG + A+ L++G+ QC A+ Sbjct: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 Query: 50 DEQFEPQKTLFIQCD----VADQQQLRDTFRKVVDHFGR---------LDILVNNAGVNN 96 D + P + D D+ L+ + + D + +++L+N AG+ Sbjct: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 Query: 97 EKNWEKT--------LQINLVSVISGTYLGLDYMSKQN------GGEGG--IIINMSSL- 139 E +T + +N +S ++ T + + YM K G+ I+N+SS+ Sbjct: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 Query: 140 -AGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVN-TAILESIEKE 197 +G M V VY ASK + FT LAA + +R I PG V T +++++ Sbjct: 186 HSGKMKVPGTSVYSASKAALSRFTE--VLAAEMEPRNIRCFTISPGLVKGTDMIQNLP-- 241 Query: 198 ENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDAL 238 +E K+ ++ I G P IA + +L AL Sbjct: 242 ------VEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTAL 276 >3D3W-A nrPDB Length = 244 Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 55/199 (27%), Positives = 94/199 (47%), Gaps = 24/199 (12%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + + G+ LVTGA +GIGR +AL GA+V V + +A LD + Sbjct: 3 LFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVS-------RTQADLDSLVRECPGIE 55 Query: 61 IQC-DVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSV 111 C D+ D + + + G +D+LVNNA V ++ ++++ ++NL +V Sbjct: 56 PVCVDLGDWE----ATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAV 111 Query: 112 ISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANL 171 I + + + + G G I+N+SS V VYC++K + T+ AL L Sbjct: 112 IQVSQIVARGLIAR--GVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMAL--EL 167 Query: 172 MNSGVRLNAICPGFVNTAI 190 +R+NA+ P V T++ Sbjct: 168 GPHKIRVNAVNPTVVMTSM 186 >5IZ4-A nrPDB Length = 271 Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 55/200 (27%), Positives = 87/200 (43%), Gaps = 20/200 (10%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQF---EPQKTLFIQC 63 V ++TG+A GIG A A G VA+ N + + A+ E +TL Sbjct: 16 VCVITGSASGIGAATALRFAQAGWSVAI--GNFDDSTRDAASTVEALCRDAGAQTLIFDA 73 Query: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVN-----------NEKNWEKTLQINLVSVI 112 DV R V + R+D L+N AG ++ +E+ ++NL+ + Sbjct: 74 DVGKDADCRHAVDMVASRWQRIDALINCAGTTRVIPHNAFDQIDDFEFERVYRVNLIGLY 133 Query: 113 SGTYLGLDYMSKQ-NGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANL 171 T + + + + ++N+SSLAGL Y ASK + T S LA NL Sbjct: 134 QMTRAAVPLLRESASATRSTSVVNVSSLAGLNGTGSSIAYAASKGAVNTLTLS--LARNL 191 Query: 172 MNSGVRLNAICPGFVNTAIL 191 +R+NA+ PG V+ +L Sbjct: 192 APH-IRVNALAPGMVDDGLL 210 >1A27-A nrPDB Length = 289 Score = 58.5 bits (140), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 64/231 (27%), Positives = 97/231 (41%), Gaps = 29/231 (12%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLE----AGVQCKAALDEQFEPQKTLFIQ 62 V L+TG + GIG A L ++ V L G +AA P +Q Sbjct: 4 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 63 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISG 114 DV D + + +V + GR+D+LV NAG+ E L +N+V + Sbjct: 64 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 121 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 L M ++ G ++ S+ GLM + VYCASK + G S LA L+ Sbjct: 122 LQAFLPDMKRRGSGR---VLVTGSVGGLMGLPFNDVYCASKFALEGLCES--LAVLLLPF 176 Query: 175 GVRLNAICPGFVNTAILESI--EKEE--------NMGQYIEYKDHIKDMIK 215 GV L+ I G V+TA +E + EE ++ +Y H K + + Sbjct: 177 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFR 227 >6CGE-A nrPDB Length = 328 Score = 58.5 bits (140), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 64/231 (27%), Positives = 97/231 (41%), Gaps = 29/231 (12%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLE----AGVQCKAALDEQFEPQKTLFIQ 62 V L+TG + GIG A L ++ V L G +AA P +Q Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISG 114 DV D + + +V + GR+D+LV NAG+ E L +N+V + Sbjct: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 L M ++ G ++ S+ GLM + VYCASK + G S LA L+ Sbjct: 123 LQAFLPDMKRRGSGR---VLVTGSVGGLMGLPFNDVYCASKFALEGLCES--LAVLLLPF 177 Query: 175 GVRLNAICPGFVNTAILESI--EKEE--------NMGQYIEYKDHIKDMIK 215 GV L+ I G V+TA +E + EE ++ +Y H K + + Sbjct: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFR 228 >3GDF-A nrPDB Length = 267 Score = 57.0 bits (136), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 54/213 (25%), Positives = 92/213 (43%), Gaps = 26/213 (12%) Query: 1 MHVNGKVALVTGAA--QGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKT 58 + + GKV +VTGA+ +G+G A GA VA+ + G + E+ K Sbjct: 16 LSLKGKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKTYGIKA 75 Query: 59 LFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKN--------WEKTLQINLVS 110 +C V + + VV FG++D + NAG + W +Q++L Sbjct: 76 KAYKCQVDSYESCEKLVKDVVADFGQIDAFIANAGATADSGILDGSVEAWNHVVQVDL-- 133 Query: 111 VISGTY-----LGLDYMSKQNGGEGGIIINMSSLAGLMPVAQ-QPVYCASKHGIVGFTRS 164 +GT+ +G + + G G ++I S + Q Q Y +K G + RS Sbjct: 134 --NGTFHCAKAVGHHFKER---GTGSLVITASMSGHIANFPQEQTSYNVAKAGCIHMARS 188 Query: 165 AALAANLMNSGVRLNAICPGFVNTAILESIEKE 197 A N R+N+I PG+++T + + + KE Sbjct: 189 LA---NEWRDFARVNSISPGYIDTGLSDFVPKE 218 >1H5Q-A nrPDB Length = 265 Score = 57.0 bits (136), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 66/248 (26%), Positives = 109/248 (43%), Gaps = 30/248 (12%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 K +VTG +GIG AF A+ GA VA++ + V+ + ++F KT QCDV Sbjct: 15 KTIIVTGGNRGIGLAFTRAVAAAGANVAVIYRSAADAVEVTEKVGKEFGV-KTKAYQCDV 73 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISGTY- 116 ++ + T +++ G + L+ NAGV+ +++ +N+ V + Sbjct: 74 SNTDIVTKTIQQIDADLGPISGLIANAGVSVVKPATELTHEDFAFVYDVNVFGVFNTCRA 133 Query: 117 LGLDYMSKQNGGE-------GGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAA 169 + ++ KQ G IIN SSL G + Q Y +SK + LAA Sbjct: 134 VAKLWLQKQQKGSIVVTSSMSSQIINQSSLNGSLT---QVFYNSSKAACSNLVK--GLAA 188 Query: 170 NLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGL 229 ++G+R+NA+ PG+VNT ++K + +DH I P + Sbjct: 189 EWASAGIRVNALSPGYVNTDQTAHMDK--------KIRDHQASNIPLNRFAQPEEMTGQA 240 Query: 230 ITLIEDDA 237 I L+ D A Sbjct: 241 ILLLSDHA 248 >1CYD-A nrPDB Length = 244 Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 60/247 (24%), Positives = 111/247 (44%), Gaps = 36/247 (14%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWN----LEAGVQCKAALDEQFEPQ 56 ++ +G ALVTGA +GIGR +AL GAKV V + +C EP Sbjct: 3 LNFSGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPG-----IEP- 56 Query: 57 KTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINL 108 + D+ D D K + G +D+LVNNA + ++ ++++ +NL Sbjct: 57 ----VCVDLGDW----DATEKALGGIGPVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNL 108 Query: 109 VSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALA 168 SV + + M N G G I+N+SS+ + Y ++K + T+ A+A Sbjct: 109 RSVFQVSQMVARDM--INRGVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTK--AMA 164 Query: 169 ANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANG 228 L +R+N++ P V T + + + + + ++ + ++ K+ + D + N Sbjct: 165 MELGPHKIRVNSVNPTVVLTDMGKKVSADPEFARKLKERHPLR---KFAEVED---VVNS 218 Query: 229 LITLIED 235 ++ L+ D Sbjct: 219 ILFLLSD 225 >2BGM-A nrPDB Length = 278 Score = 54.3 bits (129), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 43/185 (23%), Positives = 79/185 (42%), Gaps = 21/185 (11%) Query: 22 AEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVVDH 81 A+ + GAKV + D + G + + P F+ CDV + +R+ + Sbjct: 33 AKLFVRYGAKVVIADIADDHG---QKVCNNIGSPDVISFVHCDVTKDEDVRNLVDTTIAK 89 Query: 82 FGRLDILVNNAGV----------NNEKNWEKTLQINLVSVISGTYLGLDYMSKQ--NGGE 129 G+LDI+ N GV +++++ + IN + G +L + ++ + Sbjct: 90 HGKLDIMFGNVGVLSTTPYSILEAGNEDFKRVMDIN----VYGAFLVAKHAARVMIPAKK 145 Query: 130 GGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTA 189 G I+ S + VY A+KH ++G T S L L G+R+N + P V + Sbjct: 146 GSIVFTASISSFTAGEGVSHVYTATKHAVLGLTTS--LCTELGEYGIRVNCVSPYIVASP 203 Query: 190 ILESI 194 +L + Sbjct: 204 LLTDV 208 >2NWQ-A nrPDB Length = 272 Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 48/189 (25%), Positives = 78/189 (41%), Gaps = 16/189 (8%) Query: 9 LVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQ 68 +TGA G G A A G + L E + +A E + L + DV D+ Sbjct: 25 FITGATSGFGEACARRFAEAGWSLVLTGRREE---RLQALAGELSAKTRVLPLTLDVRDR 81 Query: 69 QQLRDTFRKVVDHFGRLDILVNNAGVN---------NEKNWEKTLQINLVSVISGTYLGL 119 + + + F L L+NNAG+ + +W+ + N+ ++ T L L Sbjct: 82 AAMSAAVDNLPEEFATLRGLINNAGLALGTDPAQSCDLDDWDTMVDTNIKGLLYSTRLLL 141 Query: 120 DYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLN 179 + G G I+N+ S+AG P VY +K + F S L +L +GVR+ Sbjct: 142 PRLIAH--GAGASIVNLGSVAGKWPYPGSHVYGGTKAFVEQF--SLNLRCDLQGTGVRVT 197 Query: 180 AICPGFVNT 188 + PG + Sbjct: 198 NLEPGLCES 206 >3KZV-A nrPDB Length = 254 Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 59/207 (28%), Positives = 95/207 (45%), Gaps = 24/207 (11%) Query: 5 GKVALVTGAAQGIGRAFAEALL-LKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63 GKV LVTG ++GIG++ + L L V EA ++ L E++ + ++ Sbjct: 2 GKVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARSEAPLK---KLKEKYG-DRFFYVVG 57 Query: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGV------NNEKN---WEKTLQINLVSVISG 114 D+ + L+ V G++D LV NAGV NE + W+K IN S++S Sbjct: 58 DITEDSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNEIDVNAWKKLYDINFFSIVSL 117 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 + L + K NG ++ +SS A M + Y +SK + F + A Sbjct: 118 VGIALPELKKTNGN----VVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANE----ER 169 Query: 175 GVRLNAICPGFVNTAILESIEKEENMG 201 V+ A+ PG V+T + +I EN+G Sbjct: 170 QVKAIAVAPGIVDTDMQVNI--RENVG 194 >1O5I-A nrPDB Length = 249 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 50/220 (22%), Positives = 100/220 (45%), Gaps = 25/220 (11%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + + K LV A++GIGRA A+ L +GA+V + N +E + + Sbjct: 15 LGIRDKGVLVLAASRGIGRAVADVLSQEGAEVTICARN-----------EELLKRSGHRY 63 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGL- 119 + CD+ ++ L F KV + +DILV NAG +++ + I +L + Sbjct: 64 VVCDL--RKDLDLLFEKVKE----VDILVLNAGGPKAGFFDELTNEDFKEAIDSLFLNMI 117 Query: 120 ----DYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSG 175 +Y+ G I+ ++S + + P+ +++ + GF ++ L+ + G Sbjct: 118 KIVRNYLPAMKEKGWGRIVAITSFSVISPIENLYTSNSARMALTGFLKT--LSFEVAPYG 175 Query: 176 VRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIK 215 + +N + PG+ T ++ + EE Q +E + ++ M K Sbjct: 176 ITVNCVAPGWTETERVKELLSEEKKKQ-VESQIPMRRMAK 214 >1P33-A nrPDB Length = 289 Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 55/224 (24%), Positives = 87/224 (38%), Gaps = 44/224 (19%) Query: 4 NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63 VALVTGAA+ +G + AEAL +G V L A AA P + +Q Sbjct: 6 TAPVALVTGAAKRLGSSIAEALHAEGYTVCLHYHRSAADASTLAATLNARRPNSAITVQA 65 Query: 64 DVAD-------------QQQLRDTFRKVVD----HFGRLDILVNNAGV------------ 94 D+++ L +VD H+GR D+LVNNA Sbjct: 66 DLSNVATASFSETDGSVPVTLFSRCSALVDACYMHWGRCDVLVNNASSFYPTPLLRKDAG 125 Query: 95 --NNEKNWEKTLQINLVSVISGTYLGLDYMSK-----------QNGGEGGIIINMSSLAG 141 + +++L++ + + ++ K + G I+NM Sbjct: 126 EGGSSVGDKESLEVAAADLFGSNAIAPYFLIKAFAQRVADTRAEQRGTSYSIVNMVDAMT 185 Query: 142 LMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGF 185 P+ +Y +K + G TRSAAL L + +R+N + PG Sbjct: 186 SQPLLGYTMYTMAKEALEGLTRSAAL--ELASLQIRVNGVSPGL 227 >2BFA-A nrPDB Length = 288 Score = 51.6 bits (122), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 61/222 (27%), Positives = 88/222 (39%), Gaps = 44/222 (19%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 VALVTGAA+ +GR+ AE L +G V L A +A P + +Q D+ Sbjct: 7 PVALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADL 66 Query: 66 ----------ADQQQLRDTFRKVVD-------HFGRLDILVNNAGV--------NNEKNW 100 AD F + + H+GR D+LVNNA N+E Sbjct: 67 SNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGH 126 Query: 101 E---------KTLQINLV--SVISGTYLGLDYMSKQNG------GEGGIIINMSSLAGLM 143 E +T +L + I+ +L + + G G IINM Sbjct: 127 EPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQ 186 Query: 144 PVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGF 185 P+ +Y +K + G TRSAAL L +R+N + PG Sbjct: 187 PLLGYTIYTMAKGALEGLTRSAAL--ELAPLQIRVNGVGPGL 226 >2QHX-A nrPDB Length = 328 Score = 51.2 bits (121), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 61/222 (27%), Positives = 88/222 (39%), Gaps = 44/222 (19%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 VALVTGAA+ +GR+ AE L +G V L A +A P + +Q D+ Sbjct: 47 PVALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADL 106 Query: 66 ----------ADQQQLRDTFRKVVD-------HFGRLDILVNNAGV--------NNEKNW 100 AD F + + H+GR D+LVNNA N+E Sbjct: 107 SNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGH 166 Query: 101 E---------KTLQINLV--SVISGTYLGLDYMSKQNG------GEGGIIINMSSLAGLM 143 E +T +L + I+ +L + + G G IINM Sbjct: 167 EPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQ 226 Query: 144 PVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGF 185 P+ +Y +K + G TRSAAL L +R+N + PG Sbjct: 227 PLLGYTIYTMAKGALEGLTRSAAL--ELAPLQIRVNGVGPGL 266 >5LCX-A nrPDB Length = 316 Score = 50.8 bits (120), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 34/92 (36%), Positives = 48/92 (52%), Gaps = 2/92 (2%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQF--EPQKTLFIQC 63 + ALVTGA +GIG L KG V L N + G++ + L ++ + +F Q Sbjct: 8 RYALVTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKELNVSENRLVFHQL 67 Query: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVN 95 DV D + + FG+LDILVNNAGV+ Sbjct: 68 DVTDLASVAAVAVFIKSKFGKLDILVNNAGVS 99 >3U4C-A nrPDB Length = 281 Score = 48.9 bits (115), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 27/90 (30%), Positives = 46/90 (51%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 H++ + A V GA+QGIG+A A L + + + NL+ K + + + + Sbjct: 20 HMSKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVL 79 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNN 91 D++DQ F+K+ GRLD+L+NN Sbjct: 80 AGDMSDQHTRAGIFQKIESQCGRLDVLINN 109 >5L51-A nrPDB Length = 324 Score = 48.5 bits (114), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 3/93 (3%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI---Q 62 + A+VTGA +GIG + L KG V L + + G++ + L ++ + ++ Q Sbjct: 16 RYAVVTGANKGIGFEICKQLASKGITVILASRDEKRGIEARERLIKELGSEFGDYVVSQQ 75 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN 95 DVAD + + FG LDILVNNAG+N Sbjct: 76 LDVADPASVAALVDFIKTKFGSLDILVNNAGLN 108 >4NR0-A nrPDB Length = 273 Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 54/215 (25%), Positives = 87/215 (40%), Gaps = 26/215 (12%) Query: 3 VNGKVALVTGAAQ--GIGRAFAEALLLKGAKVALVDWN--LEAGVQCKAALDEQFEPQKT 58 + GK AL+ G A I A A+ +GA++A N L V+ A+ + + Sbjct: 4 LTGKRALIVGVASKLSIASGIAAAMHREGAELAFTYQNDKLRGRVEEFAS---GWGSRPE 60 Query: 59 LFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAG-------------VNNEKNWEKTLQ 105 L CDVAD Q+ F + H+ LDI+V++ G V + + Sbjct: 61 LCFPCDVADDSQIEAVFAALGKHWDGLDIIVHSVGFAPGDQLDGDFTAVTTREGFRIAHD 120 Query: 106 INLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSA 165 I+ S I+ G + M +NG ++ +S L + V +K + R Sbjct: 121 ISAYSFIALAKAGREMMKGRNGS----LLTLSYLGAERTMPNYNVMGMAKASLEAGVRY- 175 Query: 166 ALAANLMNSGVRLNAICPGFVNTAILESIEKEENM 200 LA +L G R+NA+ G + T I+ M Sbjct: 176 -LAGSLGAEGTRVNAVSAGPIRTLAASGIKSFRKM 209 >5PGZ-A nrPDB Length = 276 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 48/194 (24%), Positives = 77/194 (39%), Gaps = 13/194 (6%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 + GK +VTGA++GIGR A L GA V L + E G+Q + + +I Sbjct: 16 LQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARS-EEGLQKVVSRCLELGAASAHYIA 74 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVISG 114 + D K G LD+L+ N + + +++N +S + Sbjct: 75 GTMEDMTFAEQFIVKAGKLMGGLDMLILNHITQTSLSLFHDDIHSVRRVMEVNFLSYVVM 134 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 + L + + NG I +SSLAG M Y ASK + GF + + Sbjct: 135 STAALPMLKQSNGS----IAVISSLAGKMTQPMIAPYSASKFALDGFFSTIRTELYITKV 190 Query: 175 GVRLNAICPGFVNT 188 V + G ++T Sbjct: 191 NVSITLCVLGLIDT 204 >3O26-A nrPDB Length = 311 Score = 45.1 bits (105), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 31/90 (34%), Positives = 43/90 (47%), Gaps = 2/90 (2%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 + A+VTG +GIG + L G V L ++ G + L + +F Q DV Sbjct: 13 RCAVVTGGNKGIGFEICKQLSSNGIMVVLTCRDVTKGHEAVEKLKNS-NHENVVFHQLDV 71 Query: 66 ADQQQLRDTFRKVVD-HFGRLDILVNNAGV 94 D + + HFG+LDILVNNAGV Sbjct: 72 TDPIATMSSLADFIKTHFGKLDILVNNAGV 101 >2HRB-A nrPDB Length = 274 Score = 43.9 bits (102), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 50/151 (33%), Positives = 70/151 (46%), Gaps = 24/151 (15%) Query: 5 GKVALVTGAAQGIGRAFAEALLLK-GAKVALVDWNLEAGVQCKAALDE-QFEPQKTLFIQ 62 +VALVTGA +GIG A A L + V L ++ G +AA+ + Q E F Q Sbjct: 2 SRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARG---QAAVQQLQAEGLSPRFHQ 58 Query: 63 CDVADQQQ---LRDTFRKVVDHFGRLDILVNNAGVNNEKN--------WEKTLQINLVSV 111 D+ D Q LRD RK +G L++LVNNA V + + E TL+ N + Sbjct: 59 LDIDDLQSIRALRDFLRK---EYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFAT 115 Query: 112 ISGTYLGLDYMSKQNGGEGGIIINMSSLAGL 142 + L M G ++N+SSL L Sbjct: 116 RNMCNELLPIMKPH-----GRVVNISSLQCL 141 >2YW9-A nrPDB Length = 261 Score = 43.9 bits (102), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 56/206 (27%), Positives = 83/206 (40%), Gaps = 24/206 (11%) Query: 3 VNGKVALVTGAA--QGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 ++GK ALV G + +G A A L GA+VAL + E L E L Sbjct: 6 LSGKKALVMGVTNQRSLGFAIAAKLKEAGAEVAL-SYQAERLRPEAEKLAEAL--GGALL 62 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV------------NNEKNWEKTLQINL 108 + DV ++L F V + FG LD LV+ ++W L+++ Sbjct: 63 FRADVTQDEELDALFAGVKEAFGGLDYLVHAIAFAPREAMEGRYIDTRRQDWLLALEVSA 122 Query: 109 VSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALA 168 S+++ + EGG I+ ++ A V + V +K + R LA Sbjct: 123 YSLVAVARRAEPLLR-----EGGGIVTLTYYASEKVVPKYNVMAIAKAALEASVRY--LA 175 Query: 169 ANLMNSGVRLNAICPGFVNTAILESI 194 L GVR+NAI G V T SI Sbjct: 176 YELGPKGVRVNAISAGPVRTVAARSI 201 >1N5D-A nrPDB Length = 288 Score = 43.5 bits (101), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 64/241 (26%), Positives = 93/241 (38%), Gaps = 67/241 (27%) Query: 4 NGKVALVTGAAQGIGRAFAEALLLKGA-KVALVDWNLEAGVQCKAALDE-QFEPQKTLFI 61 N +VALVTGA +GIG A L + A V L ++ G +AA+ + Q E F Sbjct: 3 NTRVALVTGANKGIGFAIVRDLCRQFAGDVVLTARDVARG---QAAVKQLQAEGLSPRFH 59 Query: 62 QCDVADQQQLR---DTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLG 118 Q D+ D Q +R D RK +G LD+LVNNA + + + I + ++G Sbjct: 60 QLDIIDLQSIRALCDFLRK---EYGGLDVLVNNAAIAFQLDNPTPFHIQAELTMKTNFMG 116 Query: 119 --------LDYMSKQNGGEGGIIINMSSLAGLM------PVAQQ---------------- 148 L + Q G ++N+SS G+ P QQ Sbjct: 117 TRNVCTELLPLIKPQ-----GRVVNVSSTEGVRALNECSPELQQKFKSETITEEELVGLM 171 Query: 149 -------------------PVYCASKHGIVGFTRSAALAANLMNSG--VRLNAICPGFVN 187 Y +K G+ +R A +G + LNA CPG+V Sbjct: 172 NKFVEDTKNGVHRKEGWSDSTYGVTKIGVSVLSRIYARKLREQRAGDKILLNACCPGWVR 231 Query: 188 T 188 T Sbjct: 232 T 232 >3E9N-A nrPDB Length = 245 Score = 43.5 bits (101), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 57/230 (24%), Positives = 102/230 (44%), Gaps = 32/230 (13%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDE--QFEPQKT 58 M + K+A+VTGA G+G + L ++ +V + L + AAL E EP Sbjct: 1 MSLKKKIAVVTGATGGMGIEIVKDL----SRDHIV-YALGRNPEHLAALAEIEGVEP--- 52 Query: 59 LFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKN--------WEKTLQINLVS 110 I+ D+ ++ L + + + +D LV+ A V + W L +N++ Sbjct: 53 --IESDIV-KEVLEEGGVDKLKNLDHVDTLVHAAAVARDTTIEAGSVAEWHAHLDLNVIV 109 Query: 111 VISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAAN 170 + L + +G +I ++S AG P +Y ASKH + G + A Sbjct: 110 PAELSRQLLPALRAASG----CVIYINSGAGNGPHPGNTIYAASKHALRGL--ADAFRKE 163 Query: 171 LMNSGVRLNAICPGFVNTAILESIEKEENMG----QYIEYKDHIKDMIKY 216 N+G+R++ + PG NT +L+ + + YIE K+ I + I++ Sbjct: 164 EANNGIRVSTVSPGPTNTPMLQGLMDSQGTNFRPEIYIEPKE-IANAIRF 212 >4FC7-A nrPDB Length = 277 Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 47/188 (25%), Positives = 78/188 (41%), Gaps = 10/188 (5%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 KVA +TG GIG AE + G + +L + L ++ L + DV Sbjct: 28 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATG-RRCLPLSMDV 86 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVI-----SGTY-LGL 119 + + + FGR+DIL+N A N L N + SGT+ + Sbjct: 87 RAPPAVMAAVDQALKEFGRIDILINCA-AGNFLCPAGALSFNAFKTVMDIDTSGTFNVSR 145 Query: 120 DYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLN 179 K GG+I+N+++ G A Q ++K + TR A+ N +R+N Sbjct: 146 VLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN--IRVN 203 Query: 180 AICPGFVN 187 ++ PG ++ Sbjct: 204 SLAPGPIS 211 >1OAA-A nrPDB Length = 259 Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 69/270 (25%), Positives = 114/270 (42%), Gaps = 37/270 (13%) Query: 7 VALVTGAAQGIGRAFAEAL--LLKGAKVALVDWNLEAGV-QCKAALDEQFEPQKTLFIQC 63 V ++TGA++G GRA A L LL V LV E+ + Q K L Q K + Sbjct: 8 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAA 67 Query: 64 DVADQ---QQLRDTFRKVVDHFG--RLDILVNNAG-----------VNNEKNWEKTLQIN 107 D+ + Q+L R++ G RL +L+NNA VN+ +N Sbjct: 68 DLGTEAGVQRLLSAVRELPRPEGLQRL-LLINNAATLGDVSKGFLNVNDLAEVNNYWALN 126 Query: 108 LVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 L S++ T L+ + + G ++N+SSL L P +YCA K + L Sbjct: 127 LTSMLCLTSGTLNAF-QDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQ--VL 183 Query: 168 AANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIAN 227 AA VR+ + PG ++ ++ + +E + + E + ++ + ++D A Sbjct: 184 AAE--EPSVRVLSYAPGPLDND-MQQLARETS--KDPELRSKLQKLKSDGALVDCGTSAQ 238 Query: 228 GLITLIEDDALNGAIMKITTSKGIHFQDYD 257 L+ L++ D T G H YD Sbjct: 239 KLLGLLQKD---------TFQSGAHVDFYD 259 >3BHI-A nrPDB Length = 276 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 38/93 (40%), Positives = 48/93 (51%), Gaps = 11/93 (11%) Query: 7 VALVTGAAQGIGRAFAEALL-LKGAKVALVDWNLEAGVQCKAALDE-QFEPQKTLFIQCD 64 VALVTG +GIG A L L V L ++ G +AA+ + Q E F Q D Sbjct: 6 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRG---QAAVQQLQAEGLSPRFHQLD 62 Query: 65 VADQQQ---LRDTFRKVVDHFGRLDILVNNAGV 94 + D Q LRD RK +G LD+LVNNAG+ Sbjct: 63 IDDLQSIRALRDFLRK---EYGGLDVLVNNAGI 92 >5WQO-A nrPDB Length = 234 Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 46/168 (27%), Positives = 75/168 (44%), Gaps = 20/168 (11%) Query: 9 LVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQ 68 L+ GA++GIG A+A L +GA+V V + +A + E +Q D Sbjct: 10 LIVGASRGIGLGLADAFLQRGAQVFAVARRPQGSPGLQALAERAGE-----RLQAVTGDL 64 Query: 69 QQLRDTFRKVVDHFG--RLDILVNNAGVNN-------EKNWEKTLQINLVSVISGTYLGL 119 Q D ++ + G R+D L+ NAG+ E + E+T Q+ L + I+ L Sbjct: 65 NQ-HDCAERIGEMLGERRIDRLIVNAGIYGPQQQDVAEIDAEQTAQLFLTNAIAPLRLAR 123 Query: 120 DYMSKQNGGEGGIIINMSSLAGLMPV---AQQPVYCASKHGIVGFTRS 164 + + GG++ MSS + + A P+Y ASK + RS Sbjct: 124 ALSGRVS--RGGVVAFMSSQMASLALGLSATMPLYGASKAALNSLVRS 169 >2P91-A nrPDB Length = 285 Score = 42.0 bits (97), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 53/208 (25%), Positives = 96/208 (46%), Gaps = 27/208 (12%) Query: 3 VNGKVALVTGAA--QGIGRAFAEALLLKGAKVALV--DWNLEAGVQCKAALDEQFEPQKT 58 + GK AL+TG A + I A++ +GA++A LE V+ + + F Sbjct: 19 LEGKRALITGVANERSIAYGIAKSFHREGAQLAFTYATPKLEKRVR---EIAKGFGSD-- 73 Query: 59 LFIQCDVADQQQLRDTFRKVVDHFGRLDILVNN----------AGV--NNEKNWEKTLQI 106 L ++CDV+ + +++ + + +++G LDI+V++ GV + + ++ + I Sbjct: 74 LVVKCDVSLDEDIKNLKKFLEENWGSLDIIVHSIAYAPKEEFKGGVIDTSREGFKIAMDI 133 Query: 107 NLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAA 166 ++ S+I+ T L M +NG I+ +S V V +K + R Sbjct: 134 SVYSLIALTRELLPLMEGRNGA----IVTLSYYGAEKVVPHYNVMGIAKAALESTVRY-- 187 Query: 167 LAANLMNSGVRLNAICPGFVNTAILESI 194 LA ++ G R+NAI G V T SI Sbjct: 188 LAYDIAKHGHRINAISAGPVKTLAAYSI 215 >4Z3K-A nrPDB Length = 275 Score = 41.2 bits (95), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 66/270 (24%), Positives = 114/270 (42%), Gaps = 37/270 (13%) Query: 7 VALVTGAAQGIGRAFAEALLLK---GAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63 V L+TGA++G GR A L G+ + L N EA Q +A L + + + + Sbjct: 23 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 82 Query: 64 DV---ADQQQLRDTFRKVVDHFG--RLDILVNNAG-----------VNNEKNWEKTLQIN 107 D+ A QQL R++ G RL +L+NNAG +++ +N Sbjct: 83 DLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 141 Query: 108 LVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 L S++ T L + G ++N+SSL L P +YCA K + AL Sbjct: 142 LTSMLCLTSSVLKAFP-DSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLAL 200 Query: 168 AANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIAN 227 VR+ PG ++T ++ + +E ++ + + ++++ ++D + A Sbjct: 201 E----EPNVRVLNYAPGPLDTD-MQQLARETSVDP--DMRKGLQELKAKGKLVDCKVSAQ 253 Query: 228 GLITLIEDDALNGAIMKITTSKGIHFQDYD 257 L++L+E D G H YD Sbjct: 254 KLLSLLEKDEFK---------SGAHVDFYD 274 >4HWK-A nrPDB Length = 288 Score = 40.8 bits (94), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 66/270 (24%), Positives = 114/270 (42%), Gaps = 37/270 (13%) Query: 7 VALVTGAAQGIGRAFAEALLLK---GAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63 V L+TGA++G GR A L G+ + L N EA Q +A L + + + + Sbjct: 36 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 95 Query: 64 DV---ADQQQLRDTFRKVVDHFG--RLDILVNNAG-----------VNNEKNWEKTLQIN 107 D+ A QQL R++ G RL +L+NNAG +++ +N Sbjct: 96 DLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 154 Query: 108 LVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 L S++ T L + G ++N+SSL L P +YCA K + AL Sbjct: 155 LTSMLCLTSSVLKAFP-DSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLAL 213 Query: 168 AANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIAN 227 VR+ PG ++T ++ + +E ++ + + ++++ ++D + A Sbjct: 214 E----EPNVRVLNYAPGPLDTD-MQQLARETSVDP--DMRKGLQELKAKGKLVDCKVSAQ 266 Query: 228 GLITLIEDDALNGAIMKITTSKGIHFQDYD 257 L++L+E D G H YD Sbjct: 267 KLLSLLEKDEFK---------SGAHVDFYD 287 >3DWF-A nrPDB Length = 276 Score = 40.4 bits (93), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 47/186 (25%), Positives = 79/186 (42%), Gaps = 15/186 (8%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 + GK +VTGA++GIGR A L GA V + + EA +Q A + +I Sbjct: 9 LQGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEA-LQKVVARCLELGAASAHYIA 67 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVISG 114 + D + + + G LD+L+ N + N N K++++N S + Sbjct: 68 GSMEDMTFAEEFVAEAGNLMGGLDMLILNHVLYNRLTFFHGEIDNVRKSMEVNFHSFVVL 127 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGF--TRSAALAANLM 172 + + + + G I +SS+AG + Y ASK + GF T + N + Sbjct: 128 SVAAMPMLMQSQGS----IAVVSSVAGKITYPLIAPYSASKFALDGFFSTLRSEFLVNKV 183 Query: 173 NSGVRL 178 N + L Sbjct: 184 NVSITL 189 >3U9L-A nrPDB Length = 324 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 55/199 (27%), Positives = 87/199 (43%), Gaps = 23/199 (11%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVA-----LVDWNLEAGVQCKA--ALDEQF 53 M ++ K+ L+TGA+ G GR AEAL G +V +V N + V+ A A D Sbjct: 1 MVMSKKIILITGASSGFGRLTAEALAGAGHRVYASMRDIVGRN-ASNVEAIAGFARDNDV 59 Query: 54 EPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAG--------VNNEKNWEKTLQ 105 + +TL + DV Q + +++ GR+D+L++NAG + + + Sbjct: 60 D-LRTL--ELDVQSQVSVDRAIDQIIGEDGRIDVLIHNAGHMVFGPAEAFTPEQFAELYD 116 Query: 106 INLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSA 165 IN++S L +M +Q G I I+ SS AG P P + A + Sbjct: 117 INVLSTQRVNRAALPHMRRQKHGL-LIWISSSSSAGGTPPYLAPYFAAKAAMDAIAVQ-- 173 Query: 166 ALAANLMNSGVRLNAICPG 184 A L G+ + I PG Sbjct: 174 -YARELSRWGIETSIIVPG 191 >5KOI-A nrPDB Length = 293 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 49/201 (24%), Positives = 78/201 (38%), Gaps = 25/201 (12%) Query: 3 VNGKVALVTGAA--QGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + GK L+ G A + A+ L +GA++A G + K L EQ Sbjct: 26 MQGKRGLIMGVANNHSLAWGIAKQLAAQGAELAFTYQGDALGKRVKP-LAEQV--GSDFV 82 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAG-------------VNNEKNWEKTLQIN 107 + CDV D + F ++ +G LD LV+ G V +N+ +T+ I+ Sbjct: 83 LPCDVEDIATVDAVFEEIEKKWGGLDFLVHAIGFSDKTELKGRYADVTTRENFSRTMVIS 142 Query: 108 LVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 S M +GG I+ ++ + V +K + R L Sbjct: 143 AYSFTEVAQRAEKLMK-----DGGSILTLTYGGSTRTIPNYNVMGVAKAALEAMVRY--L 195 Query: 168 AANLMNSGVRLNAICPGFVNT 188 AA+ G+R+NAI G V T Sbjct: 196 AADYGPQGIRVNAISAGPVRT 216 >5TF4-A nrPDB Length = 274 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 39/175 (22%), Positives = 71/175 (40%), Gaps = 19/175 (10%) Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN------------EKNWEKTLQINLV 109 CDV+D + F + +G+LD LV+ G ++ E N+ T+ I++ Sbjct: 68 HCDVSDSASIDAVFNTIEKKWGKLDFLVHAIGFSDKEELSGRYVDISESNFMMTMNISVY 127 Query: 110 SVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAA 169 S+ + T MS +GG I+ ++ V V +K + + LA Sbjct: 128 SLTALTKRAEKLMS-----DGGSILTLTYYGAEKVVPNYNVMGVAKAALEASVKY--LAV 180 Query: 170 NLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPL 224 +L +R+NAI G + T I + ++ EY ++ + + D L Sbjct: 181 DLGPKHIRVNAISAGPIKTLAASGIGDFRYILKWNEYNAPLRRTVTIEEVGDSAL 235 >1W73-A nrPDB Length = 302 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 39/154 (25%), Positives = 67/154 (43%), Gaps = 19/154 (12%) Query: 48 ALDEQFEPQ---KTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------N 96 A EQ Q K IQCDV D +++T +++ G +I++NNA N + Sbjct: 65 ATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLS 124 Query: 97 EKNWEKTLQINLVSVISGTYLGLDYMSKQ--NGGEGGIIINMSSLAGLMPVAQQPVYCAS 154 W+ I V++GT + KQ +G ++++++ ++ Sbjct: 125 PNAWKTITDI----VLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASA 180 Query: 155 KHGIVGFTRSAALAANLMNSGVRLNAICPGFVNT 188 K G+ ++S LAA G+R N I PG + T Sbjct: 181 KAGVEAMSKS--LAAEWGKYGMRFNVIQPGPIKT 212 >3GRK-A nrPDB Length = 293 Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust. Identities = 53/239 (22%), Positives = 97/239 (40%), Gaps = 50/239 (20%) Query: 3 VNGKVALVTGAA--QGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEP---QK 57 + GK L+ G A + I A+A GA++A AL ++ EP + Sbjct: 29 LQGKRGLILGVANNRSIAWGIAKAAREAGAELAFT--------YQGDALKKRVEPLAEEL 80 Query: 58 TLFI--QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN------------EKNWEKT 103 F+ CDVAD + F + +G+LD LV+ G ++ E N+ T Sbjct: 81 GAFVAGHCDVADAASIDAVFETLEKKWGKLDFLVHAIGFSDKDELTGRYIDTSEANFTNT 140 Query: 104 LQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAG--------LMPVAQQPVYCASK 155 + I++ S+ + + M+ +GG I+ ++ +M VA+ + + K Sbjct: 141 MLISVYSLTAVSRRAEKLMA-----DGGSILTLTYYGAEKVMPNYNVMGVAKAALEASVK 195 Query: 156 HGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMI 214 + LA +L +R+NAI G + T I + ++ EY ++ + Sbjct: 196 Y----------LAVDLGPQNIRVNAISAGPIKTLAASGIGDFRYILKWNEYNAPLRRTV 244 >3K2E-A nrPDB Length = 296 Score = 36.6 bits (83), Expect = 0.012, Method: Compositional matrix adjust. Identities = 45/206 (21%), Positives = 85/206 (41%), Gaps = 32/206 (15%) Query: 1 MHVNGKVALVTGAA--QGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQK- 57 M + GK ++ G A + + A+A+ +GA+VAL L E F+ + Sbjct: 26 MLMEGKKGVIIGVANDKSLAWGIAKAVCAQGAEVALT------------YLSETFKKRVD 73 Query: 58 --------TLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEK----NWEKTLQ 105 L + CDV+D + + + F+ + + +G LD +V+ +++ + T Sbjct: 74 PLAESLGVKLTVPCDVSDAESVDNMFKVLAEEWGSLDFVVHAVAFSDKNELKGRYVDTSL 133 Query: 106 INLVSVISGTYLGLDYMSKQNG---GEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFT 162 N ++ + + Y++ + GG I+ +S V V K + Sbjct: 134 GNFLTSMHISCYSFTYIASKAEPLMTNGGSILTLSYYGAEKVVPHYNVMGVCKAALEASV 193 Query: 163 RSAALAANLMNSGVRLNAICPGFVNT 188 + LA +L +R+NAI G V T Sbjct: 194 K--YLAVDLGKQQIRVNAISAGPVRT 217 >5YCX-A nrPDB Length = 266 Score = 36.2 bits (82), Expect = 0.016, Method: Compositional matrix adjust. Identities = 49/199 (24%), Positives = 83/199 (41%), Gaps = 20/199 (10%) Query: 3 VNGKVALVTGAA--QGIGRAFAEALLLKGAKVALV--DWNLEAGVQCKAALDEQFEPQKT 58 + GK +V G A + I A +L GAK+ LE V+ L + E Q++ Sbjct: 6 LQGKTFVVMGVANQRSIAWGIARSLHNAGAKLIFTYAGERLERNVR---ELADTLEGQES 62 Query: 59 LFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKT---------LQINLV 109 L + CDV + ++L F + G + + + N + + L + Sbjct: 63 LVLPCDVTNDEELTACFETIKQEVGTIHGVAHCIAFANRDDLKGEFVDTSRDGFLLAQNI 122 Query: 110 SVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAA 169 S S T + + +K+ EGG I+ ++ L G V V +K + + LA Sbjct: 123 SAFSLTAVARE--AKKVMTEGGNILTLTYLGGERVVKNYNVMGVAKASLEASVKY--LAN 178 Query: 170 NLMNSGVRLNAICPGFVNT 188 +L G+R+NAI G + T Sbjct: 179 DLGQHGIRVNAISAGPIRT 197 >2HUN-A nrPDB Length = 336 Score = 35.0 bits (79), Expect = 0.037, Method: Compositional matrix adjust. Identities = 45/180 (25%), Positives = 82/180 (45%), Gaps = 28/180 (15%) Query: 9 LVTGAAQGIGRAFAEALLLKGAKVALVDWN-LEAGVQCKAALDEQFEPQKTLFIQCDVAD 67 LVTG IG F +L K +++ + L G D + +P+ T F++ DVAD Sbjct: 7 LVTGGMGFIGSNFIRYILEKHPDWEVINIDKLGYGSNPANLKDLEDDPRYT-FVKGDVAD 65 Query: 68 QQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMSKQNG 127 + +++ RKV D +V+ A ++ + +I L S + GTY L+ + ++N Sbjct: 66 YELVKELVRKV-------DGVVHLAAESHVDRSISSPEIFLHSNVIGTYTLLESIRRENP 118 Query: 128 GEGGIIINMSSLAG------------LMPVAQQPVYCASKHG----IVGFTRSAALAANL 171 + ++ + G LMP + Y A+K ++G+TR+ L A++ Sbjct: 119 EVRFVHVSTDEVYGDILKGSFTENDRLMPSSP---YSATKAASDMLVLGWTRTYNLNASI 175 >5I9N-A nrPDB Length = 276 Score = 34.3 bits (77), Expect = 0.063, Method: Compositional matrix adjust. Identities = 52/225 (23%), Positives = 87/225 (38%), Gaps = 27/225 (12%) Query: 3 VNGKVALVTG--AAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDE-QFEPQKTL 59 ++GK L+TG + + I A+A +GA++A G + K + E E L Sbjct: 4 LDGKRILLTGLLSNRSIAYGIAKACKREGAELAFT----YVGDRFKDRITEFAAEFGSEL 59 Query: 60 FIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN-------------NEKNWEKTLQI 106 CDVAD Q+ F + H+ LD LV++ G +N+ I Sbjct: 60 VFPCDVADDAQIDALFASLKTHWDSLDGLVHSIGFAPREAIAGDFLDGLTRENFRIAHDI 119 Query: 107 NLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAA 166 + S + L +S ++ +S L + +K + R Sbjct: 120 SAYSFPALAKAALPMLSDDAS-----LLTLSYLGAERAIPNYNTMGLAKAALEASVRY-- 172 Query: 167 LAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIK 211 LA +L GVR+NAI G + T I+ + ++E +K Sbjct: 173 LAVSLGAKGVRVNAISAGPIKTLAASGIKSFGKILDFVESNSPLK 217 >5CFZ-A nrPDB Length = 305 Score = 33.9 bits (76), Expect = 0.066, Method: Compositional matrix adjust. Identities = 52/228 (22%), Positives = 94/228 (41%), Gaps = 27/228 (11%) Query: 3 VNGKVALVTGAAQGIGRAF--AEALLLKGAKVALVDWN--LEAGVQCKAALDEQFEPQ-- 56 ++GK LVTG A + A+ A+A+ +GA++A N L+ V E+F Q Sbjct: 47 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRV-------EEFAAQLG 99 Query: 57 KTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVS------ 110 + +QCDVA+ + F ++ + + D V++ G + +N V+ Sbjct: 100 SDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDY-VNAVTREGFKI 158 Query: 111 ---VISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 + S +++ + + G ++ +S L + V +K + R Sbjct: 159 AHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVR---Y 215 Query: 168 AANLMN-SGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMI 214 AN M GVR+NAI G + T I+ M + E I+ + Sbjct: 216 MANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTV 263 >2O2S-A nrPDB Length = 315 Score = 33.9 bits (76), Expect = 0.073, Method: Compositional matrix adjust. Identities = 62/247 (25%), Positives = 100/247 (40%), Gaps = 46/247 (18%) Query: 1 MHVNGKVALVTGAA--QGIGRAFAEALLLKGAKVALVDWNLEAGVQCKA----ALDEQFE 54 + + G+ A V G A G G A A+ L GA+VAL W G+ K+ LDE + Sbjct: 5 IDLRGQTAFVAGVADSHGYGWAIAKHLASAGARVALGTWPPVLGLFQKSLQSGRLDEDRK 64 Query: 55 -PQKTLF-----------------IQCDVADQQQ--------LRDTFRKVVDHFGRLDIL 88 P +L + D+ D ++ +++ KV G +DIL Sbjct: 65 LPDGSLIEFAGVYPLDAAFDKPEDVPQDIKDNKRYAGVDGYTIKEVAVKVKQDLGNIDIL 124 Query: 89 VNNAGVNNE--KNWEKTLQINLVSVISGTYLGLDYMSKQNG---GEGGIIINMSSLAGLM 143 V++ E K +T + ++ S + + + G EGG + +S LA Sbjct: 125 VHSLANGPEVTKPLLETSRKGYLAASSNSAYSFVSLLQHFGPIMNEGGSAVTLSYLAAER 184 Query: 144 PVAQQPVY----CASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEEN 199 V P Y ++K + TR+ A A GVR+NAI G + + +I K Sbjct: 185 VV---PGYGGGMSSAKAALESDTRTLAWEAG-QKYGVRVNAISAGPLKSRAASAIGKSGE 240 Query: 200 MGQYIEY 206 +I+Y Sbjct: 241 K-SFIDY 246 >4JQC-A nrPDB Length = 282 Score = 33.9 bits (76), Expect = 0.082, Method: Compositional matrix adjust. Identities = 52/228 (22%), Positives = 94/228 (41%), Gaps = 27/228 (11%) Query: 3 VNGKVALVTGAAQGIGRAF--AEALLLKGAKVALVDWN--LEAGVQCKAALDEQFEPQ-- 56 ++GK LVTG A + A+ A+A+ +GA++A N L+ V E+F Q Sbjct: 24 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRV-------EEFAAQLG 76 Query: 57 KTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVS------ 110 + +QCDVA+ + F ++ + + D V++ G + +N V+ Sbjct: 77 SDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDY-VNAVTREGFKI 135 Query: 111 ---VISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 + S +++ + + G ++ +S L + V +K + R Sbjct: 136 AHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVR---Y 192 Query: 168 AANLMN-SGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMI 214 AN M GVR+NAI G + T I+ M + E I+ + Sbjct: 193 MANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTV 240 >2DKN-A nrPDB Length = 255 Score = 30.8 bits (68), Expect = 0.57, Method: Compositional matrix adjust. Identities = 15/52 (28%), Positives = 26/52 (50%), Gaps = 2/52 (3%) Query: 151 YCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQ 202 Y SK+ + R + + GVRLN + PG V T +L++ + + G+ Sbjct: 153 YAGSKYAVTCLARRNVV--DWAGRGVRLNVVAPGAVETPLLQASKADPRYGE 202 >4R86-A nrPDB Length = 304 Score = 30.4 bits (67), Expect = 0.73, Method: Compositional matrix adjust. Identities = 18/46 (39%), Positives = 24/46 (52%), Gaps = 3/46 (6%) Query: 102 KTLQINLVSVISGTYLGLD---YMSKQNGGEGGIIINMSSLAGLMP 144 +TL+ + VI GLD YMS Q+ G G I +S +AG P Sbjct: 24 QTLENTVTQVIEQNMTGLDNLMYMSSQSSGTGQATITLSFIAGTDP 69 >1FJH-A nrPDB Length = 257 Score = 30.0 bits (66), Expect = 1.2, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 27/54 (50%), Gaps = 2/54 (3%) Query: 151 YCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYI 204 Y SK+ + R A A +GVRLN I PG T +L++ ++ G+ I Sbjct: 155 YAGSKNALTVAVRKRAAAWG--EAGVRLNTIAPGATETPLLQAGLQDPRYGESI 206 >5Y7Y-B nrPDB Length = 311 Score = 30.0 bits (66), Expect = 1.2, Method: Compositional matrix adjust. Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 5/56 (8%) Query: 53 FEPQ----KTLFIQCDVADQQQLRDTFRKVVDHFGR-LDILVNNAGVNNEKNWEKT 103 ++PQ K + C DQQ LRD+F++VV G+ L ++ N E W +T Sbjct: 233 YQPQELLGKNIVEFCHPEDQQLLRDSFQQVVKLKGQVLSVMFRFRSKNREWLWVRT 288 >5Z57-V nrPDB Length = 908 Score = 29.6 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 2/68 (2%) Query: 171 LMNSGVRLNAICPGFVNTAI--LESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANG 228 L G++L + P +N L +I E + + ++Y + ++ G D P+I G Sbjct: 297 LKECGLKLTQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPIILEG 356 Query: 229 LITLIEDD 236 L + EDD Sbjct: 357 LDLVEEDD 364 >3RFT-A nrPDB Length = 267 Score = 28.9 bits (63), Expect = 2.1, Method: Compositional matrix adjust. Identities = 30/106 (28%), Positives = 46/106 (43%), Gaps = 18/106 (16%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 K LVTGAA +GR E L + L D + LD ++ +QCD+ Sbjct: 4 KRLLVTGAAGQLGRVMRERLAPMAEILRLAD---------LSPLDPAGPNEEC--VQCDL 52 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSV 111 AD V D +V+ G++ EK +E+ LQ N++ + Sbjct: 53 ADAN-------AVNAMVAGCDGIVHLGGISVEKPFEQILQGNIIGL 91 >4C9B-B nrPDB Length = 291 Score = 28.5 bits (62), Expect = 3.1, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 2/68 (2%) Query: 171 LMNSGVRLNAICPGFVNTAI--LESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANG 228 L G++L + P +N L +I E + + ++Y + ++ G D P+I G Sbjct: 182 LKECGLKLTQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPIILEG 241 Query: 229 LITLIEDD 236 L + EDD Sbjct: 242 LDLVEEDD 249 >3OIG-A nrPDB Length = 266 Score = 28.5 bits (62), Expect = 3.4, Method: Compositional matrix adjust. Identities = 42/185 (22%), Positives = 79/185 (42%), Gaps = 20/185 (10%) Query: 14 AQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDE---QFEPQKTLFIQCDVADQQQ 70 A GI R+ EA GA++ AG + + ++ E + ++ + CDV + + Sbjct: 22 AWGIARSLHEA----GARLIFT----YAGERLEKSVHELAGTLDRNDSIILPCDVTNDAE 73 Query: 71 LRDTFRKVVDHFGRLDILVNN-AGVNNEKNWEKTLQIN-----LVSVISGTYL-GLDYMS 123 + F + + G + + + A N E+ + L N L IS L + + Sbjct: 74 IETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAA 133 Query: 124 KQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICP 183 + EGG I+ ++ L G + + V +K + + LAA+L +R+N+I Sbjct: 134 RPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKY--LAADLGKENIRVNSISA 191 Query: 184 GFVNT 188 G + T Sbjct: 192 GPIRT 196 >6E3T-A nrPDB Length = 384 Score = 28.1 bits (61), Expect = 4.2, Method: Compositional matrix adjust. Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 5/56 (8%) Query: 53 FEPQ----KTLFIQCDVADQQQLRDTFRKVVDHFGR-LDILVNNAGVNNEKNWEKT 103 ++PQ K + C DQQ LRD+F++VV G+ L ++ E W +T Sbjct: 306 YQPQELLGKNIVEFCHPEDQQLLRDSFQQVVKLKGQVLSVMFRFRSKTREWLWMRT 361 >6DVV-A nrPDB Length = 443 Score = 27.7 bits (60), Expect = 5.0, Method: Compositional matrix adjust. Identities = 29/114 (25%), Positives = 49/114 (42%), Gaps = 10/114 (8%) Query: 122 MSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAI 181 + ++ G GGI M S+ G++ + + ++ ++ AA+ A +R NA Sbjct: 109 LGQETCGPGGIAYGMRSIGGVLELVDYMEKYSPNAWMLNYSNPAAIVAEATRR-LRPNA- 166 Query: 182 CPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIED 235 +N + I E M Q + KD + ++YYG L G T IED Sbjct: 167 --KILNICDM-PIGIEGRMAQIVGLKDRKQMRVRYYG-----LNHFGWWTSIED 212 >4J3F-A nrPDB Length = 280 Score = 27.7 bits (60), Expect = 5.3, Method: Compositional matrix adjust. Identities = 25/92 (27%), Positives = 46/92 (50%), Gaps = 12/92 (13%) Query: 5 GKVALVTG--AAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDE---QFEPQKTL 59 GK L+TG + + I A+A+ +GA++A Q K +++ +F P L Sbjct: 26 GKKILITGLLSNKSIAYGIAKAMHREGAELAFTYVG-----QFKDRVEKLCAEFNPAAVL 80 Query: 60 FIQCDVADQQQLRDTFRKVVDHFGRLDILVNN 91 CDV Q+++D F ++ + LD +V++ Sbjct: 81 --PCDVISDQEIKDLFVELGKVWDGLDAIVHS 110 >4GBU-A nrPDB Length = 400 Score = 27.7 bits (60), Expect = 5.3, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 24/53 (45%) Query: 165 AALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYY 217 AA NL G+R ++ A E+ K+ N Q+ KD IK IK Y Sbjct: 122 AAFPDNLARDGLRYDSASDNVFMDAEQEAKAKKANNPQHSLTKDEIKQYIKEY 174 >3UCF-A nrPDB Length = 223 Score = 27.7 bits (60), Expect = 5.4, Method: Compositional matrix adjust. Identities = 37/174 (21%), Positives = 66/174 (37%), Gaps = 18/174 (10%) Query: 47 AALDEQFEPQKTLF------IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNW 100 A L +Q E + T+ D++D++ + F + G D L+ AG Sbjct: 20 AELAKQLESEHTIVHVASRQTGLDISDEKSVYHYFETI----GAFDHLIVTAGSYAPAGK 75 Query: 101 EKTLQINLVSVISGTYLGLDYMSKQNGG----EGGIIINMSSLAGLMPVAQQPVYCASKH 156 +++ T ++ ++G +GG I S + VA V A Sbjct: 76 VVDVEVTQAKYAFDTKFWGAVLAAKHGARYLKQGGSITLTSGMLSRKVVANTYVKAAINA 135 Query: 157 GIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHI 210 I T+ LA L + +R+NAI PG T + + ++ Y + H+ Sbjct: 136 AIEATTK--VLAKEL--APIRVNAISPGLTKTEAYKGMNADDRDAMYQRTQSHL 185 >4RNU-A nrPDB Length = 400 Score = 27.7 bits (60), Expect = 5.7, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 24/53 (45%) Query: 165 AALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYY 217 AA NL G+R ++ A E+ K+ N Q+ KD IK IK Y Sbjct: 220 AAFPDNLARDGLRYDSASDNVFMDAEQEAKAKKANNPQHSLTKDEIKQYIKEY 272 >3D02-A nrPDB Length = 303 Score = 27.3 bits (59), Expect = 6.9, Method: Compositional matrix adjust. Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 12/76 (15%) Query: 67 DQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDY---MS 123 D L F+K D + +L N + NW+ V +I +Y M+ Sbjct: 71 DANVLEPVFKKARD--AGIVVLTNESPGQPSANWD-------VEIIDNEKFAAEYVEHMA 121 Query: 124 KQNGGEGGIIINMSSL 139 K+ GG+GG +I + SL Sbjct: 122 KRMGGKGGYVIYVGSL 137 >5FAU-A nrPDB Length = 849 Score = 27.3 bits (59), Expect = 7.3, Method: Compositional matrix adjust. Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 3/53 (5%) Query: 188 TAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNG 240 TAI++S+ K N I + K M G+LD P NGLITLI + G Sbjct: 742 TAIIKSVSKMANDNMNIGMVHNFKLMS---GLLDTPEGENGLITLIRTACMLG 791 >4LIS-A nrPDB Length = 371 Score = 26.9 bits (58), Expect = 8.4, Method: Compositional matrix adjust. Identities = 37/119 (31%), Positives = 50/119 (42%), Gaps = 7/119 (5%) Query: 9 LVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQ 68 LVTG IG ALL G KV + D NL E +K F Q DV D+ Sbjct: 7 LVTGGTGYIGSFTTLALLEAGYKVVVAD-NLYNSSAEALNRIELISGKKAEFAQLDVTDE 65 Query: 69 QQLRDTFRKVVDHFGRLDILVNNAGVNN-EKNWEKTLQINLVSVISGTYLGLDYMSKQN 126 F KV + +D +++ A + ++ EK L V+V GT L M + N Sbjct: 66 A----AFDKVFEAHPDIDSVIHFAALKAVGESGEKPLDYYHVNVY-GTICLLRSMVRHN 119 >4G7A-A nrPDB Length = 248 Score = 26.9 bits (58), Expect = 9.4, Method: Compositional matrix adjust. Identities = 27/105 (25%), Positives = 45/105 (42%), Gaps = 10/105 (9%) Query: 24 ALLLKGAKVALVDWNLEA--GVQCKAALDEQFEPQKTLFIQCDVADQQQLR-DTFRKVVD 80 L+ +G+ + +W+ E G + A L K F C + +Q + D KV Sbjct: 13 GLVPRGSHMLEHEWSYEGEKGPEHWAQL-------KPEFFWCKLKNQSPINIDKKYKVKA 65 Query: 81 HFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMSKQ 125 + +L++ A + N T+QIN+ + YLG Y KQ Sbjct: 66 NLPKLNLYYKTAKESEVVNNGHTIQINIKEDNTLNYLGEKYQLKQ 110 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2GDZ-A nrPDB 344 2e-95 2PNF-A nrPDB 249 7e-67 4JRO-A nrPDB 239 8e-64 2HQ1-A nrPDB 238 2e-63 3OSU-A nrPDB 234 3e-62 3RSH-A nrPDB 234 3e-62 2UVD-A nrPDB 234 3e-62 5ITV-A nrPDB 232 1e-61 3LYL-A nrPDB 232 2e-61 5CDY-A nrPDB 229 8e-61 2C07-A nrPDB 228 2e-60 3EMK-A nrPDB 227 4e-60 3FTP-A nrPDB 227 5e-60 1Q7C-A nrPDB 226 6e-60 4DMM-A nrPDB 225 2e-59 3WOH-A nrPDB 224 3e-59 2PH3-A nrPDB 220 3e-58 4M8S-A nrPDB 220 7e-58 3GRP-A nrPDB 219 9e-58 4BO1-A nrPDB 219 1e-57 2NM0-A nrPDB 219 1e-57 4CQL-A nrPDB 219 1e-57 3F9I-A nrPDB 218 2e-57 4RZH-A nrPDB 217 5e-57 4NBT-A nrPDB 217 6e-57 3OEC-A nrPDB 215 2e-56 4K6F-A nrPDB 214 3e-56 3O4R-A nrPDB 214 4e-56 2Q2Q-A nrPDB 213 6e-56 3W8F-A nrPDB 213 6e-56 4CQM-B nrPDB 213 8e-56 3EZL-A nrPDB 212 2e-55 4NBV-A nrPDB 212 2e-55 1GEG-A nrPDB 212 2e-55 2ZAT-A nrPDB 208 2e-54 2CDH-G nrPDB 208 2e-54 5VT6-A nrPDB 207 4e-54 5OVL-A nrPDB 207 4e-54 1X1T-A nrPDB 207 4e-54 3UVE-A nrPDB 206 7e-54 5YSS-A nrPDB 204 2e-53 3AUT-A nrPDB 204 3e-53 4KMS-A nrPDB 204 3e-53 1GEE-A nrPDB 204 4e-53 6NRP-A nrPDB 203 5e-53 4IIN-A nrPDB 203 5e-53 3VZS-A nrPDB 203 6e-53 3V2H-A nrPDB 203 8e-53 5OVJ-A nrPDB 202 1e-52 2CFC-A nrPDB 202 1e-52 2EW8-A nrPDB 201 3e-52 4DBZ-A nrPDB 200 4e-52 4RZI-B nrPDB 200 6e-52 3WTC-A nrPDB 200 7e-52 5OJG-A nrPDB 198 2e-51 4Z9Y-A nrPDB 198 2e-51 3T7C-A nrPDB 198 2e-51 1AE1-A nrPDB 197 3e-51 1UZM-A nrPDB 197 4e-51 4IS3-A nrPDB 197 5e-51 1K2W-A nrPDB 197 5e-51 5B1Y-A nrPDB 197 5e-51 1HXH-A nrPDB 197 6e-51 1NFF-A nrPDB 197 6e-51 3RWB-A nrPDB 196 8e-51 2O23-A nrPDB 196 9e-51 3U5T-A nrPDB 196 1e-50 5U9P-A nrPDB 195 1e-50 2AE2-A nrPDB 195 2e-50 1E3W-A nrPDB 195 2e-50 3V2G-A nrPDB 193 5e-50 4IIV-A nrPDB 193 6e-50 5EJ2-A nrPDB 193 9e-50 3WYE-A nrPDB 192 1e-49 6CI9-A nrPDB 190 7e-49 1YXM-A nrPDB 189 1e-48 4E6P-A nrPDB 188 2e-48 3R3S-A nrPDB 188 3e-48 5ILO-A nrPDB 187 5e-48 4MOW-A nrPDB 187 5e-48 5T5Q-A nrPDB 185 1e-47 3D3W-A nrPDB 183 6e-47 3A28-C nrPDB 183 9e-47 4HP8-A nrPDB 182 1e-46 3ZV3-A nrPDB 182 1e-46 1CYD-A nrPDB 181 3e-46 4AVY-A nrPDB 180 8e-46 1DOH-A nrPDB 180 8e-46 2FWM-X nrPDB 179 1e-45 2HSD-A nrPDB 178 1e-45 1AHH-A nrPDB 178 3e-45 3OIC-A nrPDB 177 5e-45 2B4Q-A nrPDB 177 6e-45 5JS6-A nrPDB 175 1e-44 4RGB-A nrPDB 175 1e-44 4TRR-A nrPDB 175 2e-44 3V8B-A nrPDB 173 6e-44 4FC7-A nrPDB 173 8e-44 1BDB-A nrPDB 171 4e-43 3UF0-A nrPDB 166 8e-42 5O3Z-A nrPDB 166 1e-41 5IZ4-A nrPDB 165 2e-41 3GDF-A nrPDB 164 4e-41 3UN1-A nrPDB 164 4e-41 2X9N-A nrPDB 162 1e-40 1H5Q-A nrPDB 162 1e-40 1O5I-A nrPDB 162 2e-40 4HBG-A nrPDB 161 4e-40 4EGF-A nrPDB 160 4e-40 3RKU-A nrPDB 160 7e-40 1B15-A nrPDB 160 8e-40 3OML-A nrPDB 159 1e-39 3PXX-A nrPDB 158 2e-39 5JY1-A nrPDB 158 3e-39 4CR6-A nrPDB 156 6e-39 2AG5-A nrPDB 156 8e-39 3PPI-A nrPDB 156 9e-39 2NWQ-A nrPDB 152 2e-37 4HWK-A nrPDB 151 3e-37 4Z3K-A nrPDB 151 3e-37 2P91-A nrPDB 150 9e-37 4DA9-A nrPDB 149 1e-36 2BGM-A nrPDB 149 1e-36 1P33-A nrPDB 149 2e-36 1OAA-A nrPDB 146 1e-35 5PGZ-A nrPDB 144 3e-35 2QHX-A nrPDB 143 6e-35 4GKB-A nrPDB 143 7e-35 2YW9-A nrPDB 143 7e-35 3DWF-A nrPDB 143 9e-35 2BFA-A nrPDB 143 1e-34 1A27-A nrPDB 142 1e-34 6CGE-A nrPDB 141 2e-34 3U4C-A nrPDB 141 2e-34 1MG5-A nrPDB 141 3e-34 3E9N-A nrPDB 137 6e-33 2HRB-A nrPDB 136 8e-33 3KZV-A nrPDB 133 5e-32 5KOI-A nrPDB 133 6e-32 1N5D-A nrPDB 131 3e-31 4NR0-A nrPDB 130 8e-31 4DRY-A nrPDB 129 2e-30 3BHI-A nrPDB 127 6e-30 5L51-A nrPDB 119 1e-27 3O26-A nrPDB 113 1e-25 3U9L-A nrPDB 104 4e-23 5WQO-A nrPDB 103 1e-22 5LCX-A nrPDB 101 3e-22 Sequences not found previously or not previously below threshold: 3OIG-A nrPDB 130 6e-31 5TF4-A nrPDB 125 2e-29 5YCX-A nrPDB 124 3e-29 3GRK-A nrPDB 122 1e-28 4M89-A nrPDB 122 2e-28 4ZJU-A nrPDB 120 8e-28 5I9N-A nrPDB 118 2e-27 1W73-A nrPDB 118 3e-27 5CFZ-A nrPDB 118 4e-27 4JQC-A nrPDB 116 8e-27 3K2E-A nrPDB 116 1e-26 4J3F-A nrPDB 113 7e-26 4NK4-A nrPDB 113 7e-26 4ALL-A nrPDB 112 1e-25 2PD3-A nrPDB 109 1e-24 1SNY-A nrPDB 101 5e-22 2DKN-A nrPDB 99 1e-21 2O2S-A nrPDB 93 2e-19 3UCF-A nrPDB 89 2e-18 5TQV-A nrPDB 88 3e-18 4Q9N-A nrPDB 84 7e-17 1FJH-A nrPDB 83 1e-16 2NTV-A nrPDB 78 4e-15 1ENP-A nrPDB 77 8e-15 4OYR-A nrPDB 75 3e-14 2PTG-A nrPDB 73 1e-13 3SLK-A nrPDB 66 2e-11 4LIS-A nrPDB 65 5e-11 3F4B-A nrPDB 62 3e-10 2PK3-A nrPDB 61 6e-10 3ORF-A nrPDB 60 1e-09 3RFT-A nrPDB 56 2e-08 1UDA-A nrPDB 55 3e-08 1OOE-A nrPDB 55 4e-08 2O2Y-A nrPDB 54 6e-08 3ENK-A nrPDB 53 1e-07 6BWL-A nrPDB 50 1e-06 1DIR-A nrPDB 50 1e-06 2NNL-D nrPDB 49 2e-06 1Z45-A nrPDB 49 2e-06 4R1T-A nrPDB 47 7e-06 1I3M-A nrPDB 47 8e-06 5B6K-A nrPDB 46 2e-05 2HUN-A nrPDB 45 4e-05 5K1S-A nrPDB 45 5e-05 2GN9-A nrPDB 44 6e-05 1ZZE-A nrPDB 44 8e-05 2Z95-A nrPDB 43 1e-04 2Q1W-A nrPDB 43 2e-04 4G5H-A nrPDB 43 2e-04 6ACF-A nrPDB 42 3e-04 1R66-A nrPDB 41 4e-04 3BIC-A nrPDB 41 4e-04 1GY8-A nrPDB 41 5e-04 6GCS-E nrPDB 41 6e-04 5YWN-A nrPDB 41 7e-04 4PVC-A nrPDB 40 8e-04 5N2I-A nrPDB 40 0.001 2PZM-A nrPDB 40 0.001 1LU9-A nrPDB 40 0.001 4J2O-A nrPDB 40 0.001 6G2J-P nrPDB 40 0.002 2C20-A nrPDB 39 0.002 1BXK-A nrPDB 39 0.002 4EUF-A nrPDB 38 0.003 1RPN-A nrPDB 38 0.003 3OND-A nrPDB 38 0.003 4K28-A nrPDB 38 0.003 4A10-A nrPDB 38 0.004 1OC2-A nrPDB 38 0.004 5GUP-L nrPDB 38 0.005 1KEU-A nrPDB 38 0.005 5INT-A nrPDB 38 0.006 1VL0-A nrPDB 37 0.007 3HFS-A nrPDB 37 0.008 2X86-A nrPDB 37 0.009 4XRR-A nrPDB 37 0.011 6DEB-A nrPDB 37 0.011 3DFZ-A nrPDB 36 0.012 5F5N-A nrPDB 36 0.012 3SXP-A nrPDB 36 0.013 1EQ2-A nrPDB 36 0.015 2EXX-A nrPDB 36 0.016 3VPX-A nrPDB 36 0.017 2GGS-A nrPDB 36 0.018 1WVG-A nrPDB 36 0.020 4KTT-E nrPDB 36 0.022 1O89-A nrPDB 36 0.022 3LK7-A nrPDB 36 0.025 4J6F-A nrPDB 35 0.027 7REQ-A nrPDB 35 0.028 1VPD-A nrPDB 35 0.028 3NJ4-A nrPDB 35 0.031 1XDW-A nrPDB 35 0.039 3WMX-A nrPDB 35 0.044 5ENV-A nrPDB 34 0.056 1DB3-A nrPDB 34 0.061 1C0L-A nrPDB 34 0.063 3PVZ-A nrPDB 34 0.067 4WOK-A nrPDB 34 0.074 6ACQ-A nrPDB 34 0.080 3HZZ-A nrPDB 34 0.080 4DGK-A nrPDB 33 0.10 3K4W-A nrPDB 33 0.11 3PEF-A nrPDB 33 0.12 4UUP-A nrPDB 33 0.13 4KDR-A nrPDB 33 0.13 4KDC-A nrPDB 33 0.14 3DMF-A nrPDB 33 0.15 4KUG-A nrPDB 33 0.16 2Q4B-A nrPDB 33 0.16 3CT4-A nrPDB 33 0.16 1MLD-A nrPDB 33 0.20 1V8B-A nrPDB 33 0.20 5UOG-A nrPDB 33 0.20 4WLE-A nrPDB 33 0.21 1YHU-C nrPDB 33 0.21 5UZH-A nrPDB 32 0.22 5LV5-A nrPDB 32 0.23 5EGS-A nrPDB 32 0.24 5NUE-A nrPDB 32 0.26 1RKX-A nrPDB 32 0.26 6C55-A nrPDB 32 0.29 3N58-A nrPDB 32 0.29 5JXW-A nrPDB 32 0.30 4B4V-A nrPDB 32 0.32 2EER-A nrPDB 32 0.32 5GXF-A nrPDB 32 0.33 1JAY-A nrPDB 32 0.34 2DFV-A nrPDB 32 0.36 2CU0-A nrPDB 31 0.36 1QYC-A nrPDB 31 0.36 1JPH-A nrPDB 31 0.40 3SC6-A nrPDB 31 0.47 2C54-A nrPDB 31 0.50 4EJ0-A nrPDB 31 0.51 2HK7-A nrPDB 31 0.53 1ZDL-A nrPDB 31 0.53 6GBN-A nrPDB 31 0.54 4J90-A nrPDB 31 0.57 3H0K-A nrPDB 31 0.63 4G2N-A nrPDB 31 0.63 2VN8-A nrPDB 31 0.65 1ZCJ-A nrPDB 31 0.67 3JTM-A nrPDB 31 0.67 3F3S-A nrPDB 31 0.67 4E0B-A nrPDB 31 0.71 3ZWA-A nrPDB 31 0.72 3X2F-A nrPDB 30 0.84 6BII-A nrPDB 30 1.0 3FFS-A nrPDB 30 1.0 3ZXS-A nrPDB 30 1.1 4QJ1-A nrPDB 30 1.2 5XW3-A nrPDB 30 1.2 2CUK-A nrPDB 30 1.2 4AP9-A nrPDB 30 1.3 6APE-A nrPDB 30 1.3 4OM8-A nrPDB 30 1.3 5MIO-C nrPDB 29 1.4 1EDZ-A nrPDB 29 1.5 3R9I-A nrPDB 29 1.6 3HDH-A nrPDB 29 1.6 2V6G-A nrPDB 29 1.6 4BKP-A nrPDB 29 1.6 3R0Q-C nrPDB 29 1.7 1F14-A nrPDB 29 1.7 2WEK-A nrPDB 29 1.7 1IE3-A nrPDB 29 1.8 3K6J-A nrPDB 29 1.8 5BUT-A nrPDB 29 1.8 4EJ6-A nrPDB 29 2.0 2HMT-A nrPDB 29 2.0 4B4O-A nrPDB 29 2.0 5AQB-A nrPDB 29 2.1 6C6P-A nrPDB 29 2.1 6BZC-A nrPDB 29 2.3 1QQV-A nrPDB 29 2.4 6H5E-B nrPDB 29 2.8 2OWO-A nrPDB 29 2.8 2D0I-A nrPDB 29 2.9 5XF9-D nrPDB 29 3.0 3L07-A nrPDB 29 3.0 1NHQ-A nrPDB 29 3.0 4A5O-A nrPDB 29 3.0 3K30-A nrPDB 28 3.1 5OCM-A nrPDB 28 3.3 4B3J-A nrPDB 28 3.3 2VS1-A nrPDB 28 3.3 4R16-A nrPDB 28 3.5 1BW9-B nrPDB 28 3.5 2YQ5-A nrPDB 28 3.6 1P0K-A nrPDB 28 3.8 1YB5-A nrPDB 28 3.9 5XVM-A nrPDB 28 3.9 2BC1-A nrPDB 28 4.0 1WDK-C nrPDB 28 4.2 3ZU2-A nrPDB 28 4.5 5TC4-A nrPDB 28 4.9 4DGS-A nrPDB 28 5.0 1IHU-A nrPDB 28 5.1 2NX9-A nrPDB 28 5.1 4LSW-A nrPDB 28 5.2 2JLA-A nrPDB 28 5.4 3GWG-A nrPDB 28 5.4 2XHZ-A nrPDB 28 5.9 4K22-A nrPDB 28 6.2 3PDU-A nrPDB 28 6.3 3FBG-A nrPDB 28 6.4 5KIA-A nrPDB 28 6.5 4GBJ-A nrPDB 27 7.0 5W4Y-A nrPDB 27 7.4 1G3N-B nrPDB 27 8.0 2DQ4-A nrPDB 27 8.4 3VVL-A nrPDB 27 8.9 2RIR-A nrPDB 27 9.0 2R5U-A nrPDB 27 9.0 6BMQ-A nrPDB 27 9.2 4PZE-A nrPDB 27 9.2 3DDL-A nrPDB 27 9.2 4N72-A nrPDB 27 9.4 5LJ6-A nrPDB 27 9.5 5A3V-A nrPDB 27 9.7 4NEC-A nrPDB 27 10.0 >2GDZ-A nrPDB Length = 267 Score = 344 bits (883), Expect = 2e-95, Method: Composition-based stats. Identities = 253/256 (98%), Positives = 254/256 (99%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAAL EQFEPQKTLFIQ Sbjct: 5 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLFIQ 64 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYM 122 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYM Sbjct: 65 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYM 124 Query: 123 SKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAIC 182 SKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAIC Sbjct: 125 SKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAIC 184 Query: 183 PGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNGAI 242 PGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNGAI Sbjct: 185 PGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNGAI 244 Query: 243 MKITTSKGIHFQDYDT 258 MKITTSKGIHFQDY + Sbjct: 245 MKITTSKGIHFQDYGS 260 >2PNF-A nrPDB Length = 248 Score = 249 bits (637), Expect = 7e-67, Method: Composition-based stats. Identities = 72/259 (27%), Positives = 122/259 (47%), Gaps = 24/259 (9%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + + GKV+LVTG+ +GIGRA AE L G+ V + + E + ++ K Sbjct: 3 IKLQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKY-GVKAHG 61 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEK--------NWEKTLQINLVSVI 112 ++ ++ ++ + F ++ + +DILVNNAG+ +K +WE+ L++NL Sbjct: 62 VEMNLLSEESINKAFEEIYNLVDGIDILVNNAGITRDKLFLRMSLLDWEEVLKVNLTGTF 121 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 T L M KQ G I+N+SS+ G Q Y +K G++GFT+S LA L Sbjct: 122 LVTQNSLRKMIKQRWGR---IVNISSVVGFTGNVGQVNYSTTKAGLIGFTKS--LAKELA 176 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 V +NA+ PGF+ T + + +E K K+ I P +AN ++ L Sbjct: 177 PRNVLVNAVAPGFIETDMTAVLSEE--------IKQKYKEQIPLGRFGSPEEVANVVLFL 228 Query: 233 IED--DALNGAIMKITTSK 249 + + G ++ + Sbjct: 229 CSELASYITGEVIHVNGGM 247 >4JRO-A nrPDB Length = 271 Score = 239 bits (611), Expect = 8e-64, Method: Composition-based stats. Identities = 74/259 (28%), Positives = 122/259 (47%), Gaps = 24/259 (9%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M + GKVA+VTG ++GIGR A L +GA + + A L + + Sbjct: 25 MTLQGKVAVVTGGSRGIGRDIAINLAKEGANIFFNYNGSPEAAEETAKLVAE-HGVEVEA 83 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVI 112 ++ +VA + + F++ ++ FGR+DILVNNAG+ + W+ + INL Sbjct: 84 MKANVAIAEDVDAFFKQAIERFGRVDILVNNAGITRDNLLMRMKEDEWDDVININLKGTF 143 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 T M KQ G+ IINM+S+ GL+ A Q Y ASK G++G T++ A L Sbjct: 144 LCTKAVSRTMMKQRAGK---IINMASVVGLIGNAGQANYVASKAGVIGLTKTT--ARELA 198 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 G+ +NA+ PGF+ T + + ++++ K+ + I IAN ++ L Sbjct: 199 PRGINVNAVAPGFITTDMTDKLDEKT--------KEAMLAQIPLGAYGTTEDIANAVLFL 250 Query: 233 IED--DALNGAIMKITTSK 249 D + G + + Sbjct: 251 ASDASKYITGQTLSVDGGM 269 >2HQ1-A nrPDB Length = 247 Score = 238 bits (607), Expect = 2e-63, Method: Composition-based stats. Identities = 75/258 (29%), Positives = 123/258 (47%), Gaps = 24/258 (9%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M + GK A+VTG+++G+G+A A L GA + L + A + + + Sbjct: 1 MQLKGKTAIVTGSSRGLGKAIAWKLGNMGANIVLNGSPASTSLDATAE-EFKAAGINVVV 59 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVI 112 + DV + + + + + +D FGR+DILVNNAG+ + K+W+ L NL S Sbjct: 60 AKGDVKNPEDVENMVKTAMDAFGRIDILVNNAGITRDTLMLKMSEKDWDDVLNTNLKSAY 119 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 T M KQ G+ IIN++S+AG++ A Q Y ASK G++GFT+S +A Sbjct: 120 LCTKAVSKIMLKQKSGK---IINITSIAGIIGNAGQANYAASKAGLIGFTKS--IAKEFA 174 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 G+ NA+ PG + T + + + + K+ + I P +AN + L Sbjct: 175 AKGIYCNAVAPGIIKTDMTDVLPD--------KVKEMYLNNIPLKRFGTPEEVANVVGFL 226 Query: 233 IEDD--ALNGAIMKITTS 248 DD + G ++ I Sbjct: 227 ASDDSNYITGQVINIDGG 244 >3OSU-A nrPDB Length = 246 Score = 234 bits (598), Expect = 3e-62, Method: Composition-based stats. Identities = 74/259 (28%), Positives = 123/259 (47%), Gaps = 25/259 (9%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M + K ALVTGA++GIGR+ A L +G VA+ + + + + + + Sbjct: 1 MKMT-KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVE-EIKAKGVDSFA 58 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVI 112 IQ +VAD +++ ++VV FG LD+LVNNAG+ + + W+ + NL V Sbjct: 59 IQANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVF 118 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + M +Q G IIN+SS+ G + Q Y A+K G++G T+SA A L Sbjct: 119 NCIQKATPQMLRQ---RSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSA--ARELA 173 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 + G+ +NA+ PGF+ + + +++ E K+ + I IAN + L Sbjct: 174 SRGITVNAVAPGFIVSDMTDALSDE--------LKEQMLTQIPLARFGQDTDIANTVAFL 225 Query: 233 IEDDA--LNGAIMKITTSK 249 D A + G + + Sbjct: 226 ASDKAKYITGQTIHVNGGM 244 >3RSH-A nrPDB Length = 251 Score = 234 bits (597), Expect = 3e-62, Method: Composition-based stats. Identities = 74/259 (28%), Positives = 125/259 (48%), Gaps = 28/259 (10%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M++ GKVALVTGA++GIG+A AE L +GAKV + L + + Sbjct: 8 MNLEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKG----- 62 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVI 112 + +V + + + + + D FG +DILVNNAG+ + + W ++ NL S+ Sbjct: 63 MALNVTNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIF 122 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + L M K+ G IIN+ S+ G M A Q Y A+K G++GFT+S +A + Sbjct: 123 RLSKAVLRGMMKKRQGR---IINVGSVVGTMGNAGQANYAAAKAGVIGFTKS--MAREVA 177 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 + GV +N + PGF+ T + +++ E+ + + + DP IA+ + L Sbjct: 178 SRGVTVNTVAPGFIETDMTKALNDEQRTATLAQ--------VPAGRLGDPREIASAVAFL 229 Query: 233 IEDDA--LNGAIMKITTSK 249 +A + G + + Sbjct: 230 ASPEAAYITGETLHVNGGM 248 >2UVD-A nrPDB Length = 246 Score = 234 bits (597), Expect = 3e-62, Method: Composition-based stats. Identities = 71/257 (27%), Positives = 122/257 (47%), Gaps = 24/257 (9%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 + GKVALVTGA++GIGRA A L +GA V + E ++ + ++ Sbjct: 2 LKGKVALVTGASRGIGRAIAIDLAKQGANVVVNYAGNEQKANEVVDEIKKL-GSDAIAVR 60 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVISG 114 DVA+ + + + ++ VD FG++DILVNNAGV + + W+ + NL V Sbjct: 61 ADVANAEDVTNMVKQTVDVFGQVDILVNNAGVTKDNLLMRMKEEEWDTVINTNLKGVFLC 120 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 T +M +Q G I+N++S+ G+ Q Y A+K G++G T+++ A L + Sbjct: 121 TKAVSRFMMRQRHGR---IVNIASVVGVTGNPGQANYVAAKAGVIGLTKTS--AKELASR 175 Query: 175 GVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIE 234 + +NAI PGF+ T + + +++ K + +I + IAN + Sbjct: 176 NITVNAIAPGFIATDMTDVLDEN--------IKAEMLKLIPAAQFGEAQDIANAVTFFAS 227 Query: 235 DD--ALNGAIMKITTSK 249 D + G + + Sbjct: 228 DQSKYITGQTLNVDGGM 244 >5ITV-A nrPDB Length = 255 Score = 232 bits (592), Expect = 1e-61, Method: Composition-based stats. Identities = 74/258 (28%), Positives = 116/258 (44%), Gaps = 19/258 (7%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M++ K L+TG A GIG A +A L + A V + D + G A+ + + F Sbjct: 3 MNLTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQG----EAMVRKENNDRLHF 58 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVI 112 +Q D+ D+ + V FG LD+L+NNAG+ +W K LQ+NL + Sbjct: 59 VQTDITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMF 118 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + L +M G IIN S+ GL+ P Y ASK G++ T+S +A + Sbjct: 119 LMSKHALKHMLAAGKG---NIINTCSVGGLVAWPDIPAYNASKGGVLQLTKS--MAVDYA 173 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 +R+N +CPG ++T + E E N G E K + + P IAN ++ L Sbjct: 174 KHQIRVNCVCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRLGKPEEIANVMLFL 233 Query: 233 IED--DALNGAIMKITTS 248 D + G+ + Sbjct: 234 ASDLSSYMTGSAITADGG 251 >3LYL-A nrPDB Length = 247 Score = 232 bits (591), Expect = 2e-61, Method: Composition-based stats. Identities = 70/259 (27%), Positives = 124/259 (47%), Gaps = 25/259 (9%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M +N KVALVTGA++GIG A AL KGA V + + + + ++ E+ K Sbjct: 1 MSLNEKVALVTGASRGIGFEVAHALASKGATVVGTATSQASAEKFENSMKEK--GFKARG 58 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVI 112 + +++D + +++ F ++ +DILVNNAG+ + W+ + NL S+ Sbjct: 59 LVLNISDIESIQNFFAEIKAENLAIDILVNNAGITRDNLMMRMSEDEWQSVINTNLSSIF 118 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + + M K+ G II++ S+ G Q YCA+K G++GF++S LA + Sbjct: 119 RMSKECVRGMMKKRWGR---IISIGSVVGSAGNPGQTNYCAAKAGVIGFSKS--LAYEVA 173 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 + + +N + PGF+ T + + + E+ K I I I +P IA + L Sbjct: 174 SRNITVNVVAPGFIATDMTDKLTDEQ--------KSFIATKIPSGQIGEPKDIAAAVAFL 225 Query: 233 IEDDA--LNGAIMKITTSK 249 ++A + G + + Sbjct: 226 ASEEAKYITGQTLHVNGGM 244 >5CDY-A nrPDB Length = 244 Score = 229 bits (585), Expect = 8e-61, Method: Composition-based stats. Identities = 74/259 (28%), Positives = 121/259 (46%), Gaps = 28/259 (10%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M GK+ALVTGA++GIGRA AE L+ +GA V + + A L E + Sbjct: 1 MSFEGKIALVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGKG----- 55 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVI 112 + +V D + + FG +DILVNNAG+ + W+ + NL SV Sbjct: 56 LMLNVVDPTSIDTVLATIRAEFGEVDILVNNAGITRDNLLMRMKDDEWQDIIDTNLTSVF 115 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + + M K+ G II + S+ G M A Q Y A+K G++GF++S LA + Sbjct: 116 RLSKAVMRAMMKKRFGR---IITIGSVVGTMGNAGQVNYAAAKAGVIGFSKS--LAREVA 170 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 + G+ +N + PGF+ T + ++ ++ G I + + D IA+ + L Sbjct: 171 SRGITVNVVAPGFIETDMTRTLTDDQRAG--------ILAQVPANRLGDAKEIASAVAFL 222 Query: 233 IEDDA--LNGAIMKITTSK 249 D+A ++G + + Sbjct: 223 ASDEASYISGETLHVNGGM 241 >2C07-A nrPDB Length = 285 Score = 228 bits (581), Expect = 2e-60, Method: Composition-based stats. Identities = 71/253 (28%), Positives = 116/253 (45%), Gaps = 25/253 (9%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 KVALVTGA +GIGR A+ L + V + ++ + + ++ DV Sbjct: 45 KVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEI--KSFGYESSGYAGDV 102 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVISGTYL 117 + ++++ + K++ +DILVNNAG+ + WE L+ NL S+ T Sbjct: 103 SKKEEISEVINKILTEHKNVDILVNNAGITRDNLFLRMKNDEWEDVLRTNLNSLFYITQ- 161 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 + G IIN+SS+ GL Q Y +SK G++GFT+S LA L + + Sbjct: 162 --PISKRMINNRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKS--LAKELASRNIT 217 Query: 178 LNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIED-- 235 +NAI PGF+++ + + I ++ K +I I + P +AN L D Sbjct: 218 VNAIAPGFISSDMTDKISEQ--------IKKNIISNIPAGRMGTPEEVANLACFLSSDKS 269 Query: 236 DALNGAIMKITTS 248 +NG + I Sbjct: 270 GYINGRVFVIDGG 282 >3EMK-A nrPDB Length = 246 Score = 227 bits (579), Expect = 4e-60, Method: Composition-based stats. Identities = 75/261 (28%), Positives = 126/261 (48%), Gaps = 28/261 (10%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + G+ ALVTGA G+G A A AL +GA V L E + A L E + Sbjct: 3 FDLTGRKALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELGE-----RIFV 57 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVI 112 +++D++ ++ +K + G +DILVNNAG+ +++W+ L +NL SV Sbjct: 58 FPANLSDREAVKALGQKAEEEMGGVDILVNNAGITRDGLFVRMSDEDWDAVLTVNLTSVF 117 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + T M ++ G IIN++S+ G+ Q YCASK G++GF++S LA + Sbjct: 118 NLTRELTHPMMRR---RNGRIINITSIVGVTGNPGQANYCASKAGLIGFSKS--LAQEIA 172 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 + V +N I PGF+ +A+ + +++ KD I I + IA ++ L Sbjct: 173 SRNVTVNCIAPGFIESAMTGKLNEKQ--------KDAIMGNIPMKRMGVGADIAAAVVYL 224 Query: 233 IEDDA--LNGAIMKITTSKGI 251 D+A + G + + + Sbjct: 225 ASDEAAYVTGQTLHVNGGMAM 245 >3FTP-A nrPDB Length = 270 Score = 227 bits (578), Expect = 5e-60, Method: Composition-based stats. Identities = 68/257 (26%), Positives = 114/257 (44%), Gaps = 25/257 (9%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 ++ +VA+VTGA++GIGRA A L +GA V AA + + Sbjct: 26 LDKQVAIVTGASRGIGRAIALELARRGAMVIGTATTEAGAEGIGAAFKQAGLEGR--GAV 83 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEK--------NWEKTLQINLVSVISG 114 +V D + + FG L++LVNNAG+ ++ W+ + NL +V Sbjct: 84 LNVNDATAVDALVESTLKEFGALNVLVNNAGITQDQLAMRMKDDEWDAVIDTNLKAVFRL 143 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 + L M K GG I+N++S+ G Q Y A+K G+ G TR ALA + + Sbjct: 144 SRAVLRPMMKA---RGGRIVNITSVVGSAGNPGQVNYAAAKAGVAGMTR--ALAREIGSR 198 Query: 175 GVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIE 234 G+ +N + PGF++T + + + +E+ +K I + P IA+ + L Sbjct: 199 GITVNCVAPGFIDTDMTKGLPQEQQTA--------LKTQIPLGRLGSPEDIAHAVAFLAS 250 Query: 235 DDA--LNGAIMKITTSK 249 A + G + + Sbjct: 251 PQAGYITGTTLHVNGGM 267 >1Q7C-A nrPDB Length = 244 Score = 226 bits (577), Expect = 6e-60, Method: Composition-based stats. Identities = 72/259 (27%), Positives = 118/259 (45%), Gaps = 28/259 (10%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M+ GK+ALVTGA++GIGRA AE L +GAKV + L + Sbjct: 1 MNFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKG----- 55 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVI 112 + +V D + K+ FG +DILVNNAG+ ++ W ++ NL SV Sbjct: 56 LMLNVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVF 115 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + + M K+ G II + S+ G M Q + A+K G++GF++S LA + Sbjct: 116 RLSKAVMRAMMKKRHGR---IITIGSVVGTMGNGGQANFAAAKAGLIGFSKS--LAREVA 170 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 + G+ +N + PGF+ T + ++ ++ G I + + IAN + L Sbjct: 171 SRGITVNVVAPGFIETDMTRALSDDQRAG--------ILAQVPAGRLGGAQEIANAVAFL 222 Query: 233 IEDDA--LNGAIMKITTSK 249 D+A + G + + Sbjct: 223 ASDEAAYITGETLHVNGGM 241 >4DMM-A nrPDB Length = 269 Score = 225 bits (573), Expect = 2e-59, Method: Composition-based stats. Identities = 73/257 (28%), Positives = 123/257 (47%), Gaps = 28/257 (10%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 + ++ALVTGA++GIGRA A L GAKVA+ + AG + + ++ Sbjct: 26 LTDRIALVTGASRGIGRAIALELAAAGAKVAVNYASS-AGAADEVVAAIAAAGGEAFAVK 84 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVISG 114 DV+ + ++ F V++ +GRLD+LVNNAG+ + +W+ L +NL V Sbjct: 85 ADVSQESEVEALFAAVIERWGRLDVLVNNAGITRDTLLLRMKRDDWQSVLDLNLGGVFLC 144 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 + M KQ G IIN++S+ G M Q Y A+K G++G T++ +A L + Sbjct: 145 SRAAAKIMLKQ---RSGRIINIASVVGEMGNPGQANYSAAKAGVIGLTKT--VAKELASR 199 Query: 175 GVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIE 234 G+ +NA+ PGF+ T + + E + ++I + +A + L Sbjct: 200 GITVNAVAPGFIATDMTSELAAE-----------KLLEVIPLGRYGEAAEVAGVVRFLAA 248 Query: 235 DDA---LNGAIMKITTS 248 D A + G ++ I Sbjct: 249 DPAAAYITGQVINIDGG 265 >3WOH-A nrPDB Length = 251 Score = 224 bits (572), Expect = 3e-59, Method: Composition-based stats. Identities = 66/259 (25%), Positives = 118/259 (45%), Gaps = 26/259 (10%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 ++GKVALVTG ++G+GRA A L GA VA+V + ++ + E+ + Sbjct: 9 LSGKVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLGGT-ARSYR 67 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVISG 114 CDV+D +Q+ + V G +DILVNNAG+ +++++ + NL Sbjct: 68 CDVSDAEQVTRCVKAVTADLGPVDILVNNAGIIRDGLAASIKDEDYDAVMNTNLKGAFLF 127 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 ++ G IIN+SS++G+ A Q Y ++K G++G T+S +A L Sbjct: 128 IKACYFGFIRK---RSGSIINISSVSGVFGSAGQANYASAKAGLIGLTKS--IAKELAER 182 Query: 175 GVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIE 234 VR NA+ PG + T + + + + + + P +A + L Sbjct: 183 NVRCNAVAPGLIATDMTQDLVDDSKRLDPVPMR----------RFGRPDEVAGLVAFLAG 232 Query: 235 DD--ALNGAIMKITTSKGI 251 D+ + G ++ + + Sbjct: 233 DESSYITGQVVCVDGGMAM 251 >2PH3-A nrPDB Length = 245 Score = 220 bits (562), Expect = 3e-58, Method: Composition-based stats. Identities = 67/257 (26%), Positives = 113/257 (43%), Gaps = 23/257 (8%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 + AL+TGA++GIGRA A L G +A+ + A + + ++ Sbjct: 2 RKALITGASRGIGRAIALRLAEDGFALAIHYGQNREKAEEVAEEARRRGSPLVAVLGANL 61 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVISGTYL 117 + + + + G LD LVNNAG+ +++WE L+ NL +V T Sbjct: 62 LEAEAATALVHQAAEVLGGLDTLVNNAGITRDTLLVRMKDEDWEAVLEANLSAVFRTTRE 121 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 + M K G I+N++S+ G++ Q Y ASK G++GFTR A+A G+ Sbjct: 122 AVKLMMKARFGR---IVNITSVVGILGNPGQANYVASKAGLIGFTR--AVAKEYAQRGIT 176 Query: 178 LNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDA 237 +NA+ PGF+ T + E + +E K+ I P +A + L+ + A Sbjct: 177 VNAVAPGFIETEMTERLPQE--------VKEAYLKQIPAGRFGRPEEVAEAVAFLVSEKA 228 Query: 238 --LNGAIMKITTSKGIH 252 + G + + H Sbjct: 229 GYITGQTLCVDGGLTPH 245 >4M8S-A nrPDB Length = 248 Score = 220 bits (560), Expect = 7e-58, Method: Composition-based stats. Identities = 74/258 (28%), Positives = 125/258 (48%), Gaps = 27/258 (10%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 ++GK+ALVTGA++GIG A A+ L GAKV + AA+ E+ Sbjct: 5 DLSGKIALVTGASRGIGAAIADTLAAAGAKVIGTATSESG----AAAISERLAQWGGEGR 60 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVIS 113 + A+ + + + + FG+LDILVNNAG+ + + W+ +Q+NL SV Sbjct: 61 VLNSAEPETVENLIADIEKTFGKLDILVNNAGITRDNLLMRMKEEEWDDIMQVNLKSVFR 120 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 + L M KQ G IIN++S+ G+M A Q Y A+K G++GF++S +A + + Sbjct: 121 ASKAVLRGMMKQRAGR---IINITSVVGVMGNAGQTNYAAAKAGLIGFSKS--MAREVGS 175 Query: 174 SGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLI 233 G+ +N + PGF++T + ++ +E + D IA+ ++ L Sbjct: 176 RGITVNCVAPGFIDTDMTRALPEET--------RQTFTAQTALGRFGDAQDIADAVLFLA 227 Query: 234 EDDA--LNGAIMKITTSK 249 D A + G + + Sbjct: 228 SDQAKYITGQTLHVNGGM 245 >3GRP-A nrPDB Length = 266 Score = 219 bits (558), Expect = 9e-58, Method: Composition-based stats. Identities = 68/261 (26%), Positives = 121/261 (46%), Gaps = 28/261 (10%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + G+ ALVTGA GIG A A +GA V L + + A L + Sbjct: 23 FKLTGRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADL-----GKDVFV 77 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVI 112 +++D++ ++ +DILVNNAG+ + ++W+ L +NL + Sbjct: 78 FSANLSDRKSIKQLAEVAEREMEGIDILVNNAGITRDGLFVRMQDQDWDDVLAVNLTAAS 137 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + T + M ++ G IIN++S+ G++ Q YCA+K G++GF++ ALA + Sbjct: 138 TLTRELIHSMMRRRYGR---IINITSIVGVVGNPGQTNYCAAKAGLIGFSK--ALAQEIA 192 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 + + +N I PGF+ +A+ + + +++ K+ I MI + IA + L Sbjct: 193 SRNITVNCIAPGFIKSAMTDKLNEKQ--------KEAIMAMIPMKRMGIGEEIAFATVYL 244 Query: 233 IEDDA--LNGAIMKITTSKGI 251 D+A L G + I + Sbjct: 245 ASDEAAYLTGQTLHINGGMAM 265 >4BO1-A nrPDB Length = 269 Score = 219 bits (558), Expect = 1e-57, Method: Composition-based stats. Identities = 72/259 (27%), Positives = 116/259 (44%), Gaps = 25/259 (9%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M + GKVALVTGA++GIG+A A L GA V + + L + + Sbjct: 23 MSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETL--KANGVEGAG 80 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVI 112 + DV+ + + T + H G+ I+VNNAG+ + W + NL S+ Sbjct: 81 LVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEWFDVVNTNLNSLY 140 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + L M+K G IIN+ S+ G M A Q Y A+K G+ GFTR ALA + Sbjct: 141 RLSKAVLRGMTKARWGR---IINIGSVVGAMGNAGQTNYAAAKAGLEGFTR--ALAREVG 195 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 + + +NA+ PGF++T + + + + ++ + I + IA + L Sbjct: 196 SRAITVNAVAPGFIDTDMTRELPEAQ--------REALLGQIPLGRLGQAEEIAKVVGFL 247 Query: 233 IEDDA--LNGAIMKITTSK 249 D A + GA + + Sbjct: 248 ASDGAAYVTGATVPVNGGM 266 >2NM0-A nrPDB Length = 253 Score = 219 bits (557), Expect = 1e-57, Method: Composition-based stats. Identities = 69/256 (26%), Positives = 118/256 (46%), Gaps = 36/256 (14%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 + LVTG +GIG A A A G KVA+ + E P+ L ++CD+ Sbjct: 22 RSVLVTGGNRGIGLAIARAFADAGDKVAITYRSGE-------------PPEGFLAVKCDI 68 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISGTYL 117 D +Q+ ++++ + G +++L+ NAGV +E+++ ++ NL Sbjct: 69 TDTEQVEQAYKEIEETHGPVEVLIANAGVTKDQLLMRMSEEDFTSVVETNLTGTFRVVKR 128 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 M + G ++ +SS+ GL+ A Q Y ASK G+VGF RS LA L + + Sbjct: 129 ANRAMLRAKKGR---VVLISSVVGLLGSAGQANYAASKAGLVGFARS--LARELGSRNIT 183 Query: 178 LNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDA 237 N + PGFV+T + + + E+ + +I + P IA + L DDA Sbjct: 184 FNVVAPGFVDTDMTKVLTDEQ--------RANIVSQVPLGRYARPEEIAATVRFLASDDA 235 Query: 238 --LNGAIMKITTSKGI 251 + GA++ + G+ Sbjct: 236 SYITGAVIPVDGGLGM 251 >4CQL-A nrPDB Length = 261 Score = 219 bits (557), Expect = 1e-57, Method: Composition-based stats. Identities = 72/263 (27%), Positives = 120/263 (45%), Gaps = 28/263 (10%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALD-----EQFEPQ 56 + +ALVTGA GIGRA + L +GA VA D + A + L E Sbjct: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 Query: 57 KTLFIQCDVADQQQLRDTFRKVVDHFGRL-DILVNNAGVNNEK--------NWEKTLQIN 107 Q DV++ + R +V F R ++V+ AG+ ++ +W+K + +N Sbjct: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 Query: 108 LVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 L T + + G G IIN+SS+ G + Q Y ASK G++G T++A Sbjct: 128 LKGTFLVTQAAAQALV--SNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTA-- 183 Query: 168 AANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIAN 227 A L G+R N++ PGF+ T + + + + + D I +MI + DP +A+ Sbjct: 184 ARELGRHGIRCNSVLPGFIATPMTQKVPQ--------KVVDKITEMIPMGHLGDPEDVAD 235 Query: 228 GLITLIEDD--ALNGAIMKITTS 248 + L +D + G +++T Sbjct: 236 VVAFLASEDSGYITGTSVEVTGG 258 >3F9I-A nrPDB Length = 249 Score = 218 bits (555), Expect = 2e-57, Method: Composition-based stats. Identities = 66/259 (25%), Positives = 124/259 (47%), Gaps = 32/259 (12%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + + GK +L+TGA+ GIG A A L G+KV + N E AL + + + Sbjct: 10 IDLTGKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYTIE---- 65 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVI 112 C++A++++ + K + LDILV NAG+ ++ ++++K + INL + Sbjct: 66 -VCNLANKEECSNLISKTSN----LDILVCNAGITSDTLAIRMKDQDFDKVIDINLKANF 120 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + M ++ G IIN+SS+ G+ Q YCASK G++G T+S L+ + Sbjct: 121 ILNREAIKKMIQKRYGR---IINISSIVGIAGNPGQANYCASKAGLIGMTKS--LSYEVA 175 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 G+ +NA+ PGF+ + + + + +++ ++ I I P +A + L Sbjct: 176 TRGITVNAVAPGFIKSDMTDKLNEKQ--------REAIVQKIPLGTYGIPEDVAYAVAFL 227 Query: 233 IEDDA--LNGAIMKITTSK 249 ++A + G + + Sbjct: 228 ASNNASYITGQTLHVNGGM 246 >4RZH-A nrPDB Length = 247 Score = 217 bits (552), Expect = 5e-57, Method: Composition-based stats. Identities = 75/258 (29%), Positives = 121/258 (46%), Gaps = 28/258 (10%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 + +VALVTGA++GIG+A A AL G KV + A + + + +Q Sbjct: 4 LTAQVALVTGASRGIGKATALALAATGMKVVVNYAQSSTAADAVVA-EIIANGGEAIAVQ 62 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVISG 114 +VA+ ++ + +D F R+D+LVNNAG+ + ++W+ + +NL V Sbjct: 63 ANVANADEVDQLIKTTLDKFSRIDVLVNNAGITRDTLLLRMKLEDWQAVIDLNLTGVFLC 122 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 T M KQ G IIN++S+AG+M Q Y A+K G++GFT++ +A L + Sbjct: 123 TKAVSKLMLKQKSGR---IINITSVAGMMGNPGQANYSAAKAGVIGFTKT--VAKELASR 177 Query: 175 GVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIE 234 GV +NA+ PGF+ T + E++ E I I P +A + L Sbjct: 178 GVTVNAVAPGFIATDMTENLNAE-----------PILQFIPLARYGQPEEVAGTIRFLAT 226 Query: 235 DDA---LNGAIMKITTSK 249 D A + G + Sbjct: 227 DPAAAYITGQTFNVDGGM 244 >4NBT-A nrPDB Length = 240 Score = 217 bits (552), Expect = 6e-57, Method: Composition-based stats. Identities = 74/258 (28%), Positives = 118/258 (45%), Gaps = 32/258 (12%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 + GKVA++TG A+G+G+A A A +GAKV D D + + Sbjct: 3 KLEGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDLG-----------DLTYSHPNVEGM 51 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVIS 113 +V D + ++ V+D +G++DILVNNAG+ E W+ + +NL V + Sbjct: 52 YLNVTDVTGVEKFYQSVIDKYGKIDILVNNAGITKDAMTRKMTEAQWDAVIDVNLKGVFN 111 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 T L M G IIN+SS+ G+ Q Y A+K G++G T + A L Sbjct: 112 LTRLVGPQMQTNGYG---SIINISSVVGVFGNIGQANYAATKAGVIGLTMTWAKEFALKG 168 Query: 174 SGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLI 233 + VR+NAI PG++ T IL+++ ++ D + + P IA + L Sbjct: 169 ANVRVNAIAPGYIMTDILKTVPQD--------LLDKFAALTMLNRLGQPEEIAKVALFLA 220 Query: 234 EDDA--LNGAIMKITTSK 249 DDA + G + + Sbjct: 221 SDDASYVTGQTINVNGGM 238 >3OEC-A nrPDB Length = 317 Score = 215 bits (547), Expect = 2e-56, Method: Composition-based stats. Identities = 75/275 (27%), Positives = 125/275 (45%), Gaps = 31/275 (11%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDW-----NLEAGVQCKAALDE----- 51 + GKVA +TGAA+G GR A L GA + +D NL+ L E Sbjct: 43 RLQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKETVRLV 102 Query: 52 QFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKT 103 + + ++ + Q DV D L+ + + FG +DILV+N G++ ++ W Sbjct: 103 EEQGRRIIARQADVRDLASLQAVVDEALAEFGHIDILVSNVGISNQGEVVSLTDQQWSDI 162 Query: 104 LQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTR 163 LQ NL+ L M ++ G+GG +I +SS GL Q Y ASKHG+ G Sbjct: 163 LQTNLIGAWHACRAVLPSMIER--GQGGSVIFVSSTVGLRGAPGQSHYAASKHGVQGLML 220 Query: 164 SAALAANLMNSGVRLNAICPGFVNTAILES-------IEKEENMGQYIEYKDHIKDMIKY 216 S LA + +R+N++ PG VNT + + + EN + + + + Sbjct: 221 S--LANEVGRHNIRVNSVNPGAVNTEMALNEKLLKMFLPHLENPTREDAAELFSQLTLLP 278 Query: 217 YGILDPPLIANGLITLIEDDA--LNGAIMKITTSK 249 ++P ++N + L D+A ++GA + + + Sbjct: 279 IPWVEPEDVSNAVAWLASDEARYIHGAAIPVDGGQ 313 >4K6F-A nrPDB Length = 255 Score = 214 bits (546), Expect = 3e-56, Method: Composition-based stats. Identities = 67/260 (25%), Positives = 117/260 (45%), Gaps = 23/260 (8%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 + ++A+VTG G+G A + L G +V + G + ++ Sbjct: 9 MTKRIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNTGADRW-LTEMHAAGREFHAYP 67 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVISG 114 DVAD + K+V G +DILVNNAG+ + NW+ ++ NL SV + Sbjct: 68 VDVADHDSCQQCIEKIVRDVGPVDILVNNAGITRDMTLRKLDKVNWDAVIRTNLDSVFNM 127 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 T D M ++ G I+N+SS+ G Q Y A+K G+ GFT+S LA + Sbjct: 128 TKPVCDGMVERGWGR---IVNISSVNGSKGSVGQTNYAAAKAGMHGFTKS--LALEIARK 182 Query: 175 GVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIE 234 GV +N + PG++ T ++ +I ++ + + I + P +A + L Sbjct: 183 GVTVNTVSPGYLATKMVTAIPQDILDTKILP-------QIPAGRLGKPEEVAALVAYLCS 235 Query: 235 DDA--LNGAIMKITTSKGIH 252 ++A + G+ + I + +H Sbjct: 236 EEAGFVTGSNIAINGGQHMH 255 >3O4R-A nrPDB Length = 261 Score = 214 bits (545), Expect = 4e-56, Method: Composition-based stats. Identities = 69/258 (26%), Positives = 111/258 (43%), Gaps = 24/258 (9%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 + KVALVT + GIG A A L GA V + + Q A L Q E Sbjct: 13 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATL--QGEGLSVTGTV 70 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN---------NEKNWEKTLQINLVSVIS 113 C V + V G +DILV+NA VN E+ W+KTL IN+ + Sbjct: 71 CHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPAL 130 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 T + M K+ GG ++ +SS+A P Y SK ++G T++ LA L Sbjct: 131 MTKAVVPEMEKRG---GGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKT--LAIELAP 185 Query: 174 SGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLI 233 +R+N + PG + T+ + ++ E ++ +K+ ++ + +P A + L Sbjct: 186 RNIRVNCLAPGLIKTSFSRMLWMDK------EKEESMKETLRIRRLGEPEDCAGIVSFLC 239 Query: 234 EDDA--LNGAIMKITTSK 249 +DA + G + + Sbjct: 240 SEDASYITGETVVVGGGT 257 >2Q2Q-A nrPDB Length = 255 Score = 213 bits (543), Expect = 6e-56, Method: Composition-based stats. Identities = 74/259 (28%), Positives = 117/259 (45%), Gaps = 22/259 (8%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 + GK ALVTG+ GIG A+ L GA + L + G A + K + Sbjct: 2 LKGKTALVTGSTSGIGLGIAQVLARAGANIVLNGF----GDPAPALAEIARHGVKAVHHP 57 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVISG 114 D++D Q+ F FG +DILVNNAG+ + ++W+K + +NL +V G Sbjct: 58 ADLSDVAQIEALFALAEREFGGVDILVNNAGIQHVAPVEQFPLESWDKIIALNLSAVFHG 117 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 T L L M +N G IIN++S+ GL+ + Y A+KHG+VG T+ L S Sbjct: 118 TRLALPGMRARNWGR---IINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGL--ETATS 172 Query: 175 GVRLNAICPGFVNTAILESIEKEENMGQYIEYK---DHIKDMIKYYGILDPPLIANGLIT 231 V NAICPG+V T +++ + + D + + + P + ++ Sbjct: 173 NVTCNAICPGWVLTPLVQKQIDDRAANGGDPLQAQHDLLAEKQPSLAFVTPEHLGELVLF 232 Query: 232 LIEDDA--LNGAIMKITTS 248 L + + GA + Sbjct: 233 LCSEAGSQVRGAAWNVDGG 251 >3W8F-A nrPDB Length = 260 Score = 213 bits (543), Expect = 6e-56, Method: Composition-based stats. Identities = 75/260 (28%), Positives = 120/260 (46%), Gaps = 19/260 (7%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 + GK A+VTG+ GIG A A L GA V + + ++ + + E K ++ Sbjct: 2 LKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVKAYYLN 61 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVISG 114 D++D Q RD K + G LDILVNNAG+ + W + +NL +V G Sbjct: 62 ADLSDAQATRDFIAKAAEALGGLDILVNNAGIQHTAPIEEFPVDKWNAIIALNLSAVFHG 121 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 T L M KQ G IIN++S GL+ + Y A+KHG+VG T+ AL Sbjct: 122 TAAALPIMQKQGWGR---IINIASAHGLVASVNKSAYVAAKHGVVGLTKVTAL--ENAGK 176 Query: 175 GVRLNAICPGFVNTAIL----ESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLI 230 G+ NAICPG+V T ++ E+I +++ + ++ + + + P + + Sbjct: 177 GITCNAICPGWVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQPSLQFVTPEQLGGAAV 236 Query: 231 TLIE--DDALNGAIMKITTS 248 L D + G + + Sbjct: 237 FLSSAAADQMTGTTLSLDGG 256 >4CQM-B nrPDB Length = 244 Score = 213 bits (542), Expect = 8e-56, Method: Composition-based stats. Identities = 75/252 (29%), Positives = 126/252 (50%), Gaps = 29/252 (11%) Query: 5 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64 KV V G ++GIGRA A+ + KG ++A++ NLE L L CD Sbjct: 9 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL-----GGDHLAFSCD 63 Query: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKT--------LQINLVSVISGTY 116 VA + +++TF ++ H GR++ LVN AG+N + +T L NL+ + Sbjct: 64 VAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCK 123 Query: 117 LGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGV 176 + M +Q +GG I+N+ S+ GL + Q VY ASK G+VGF+R ALA + + Sbjct: 124 AAMRTMIQQ---QGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSR--ALAKEVARKKI 178 Query: 177 RLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDD 236 R+N + PGFV+T + + +++E H+K I + +A+ ++ L+E Sbjct: 179 RVNVVAPGFVHTDMTKDLKEE-----------HLKKNIPLGRFGETIEVAHAVVFLLESP 227 Query: 237 ALNGAIMKITTS 248 + G ++ + Sbjct: 228 YITGHVLVVDGG 239 >3EZL-A nrPDB Length = 256 Score = 212 bits (539), Expect = 2e-55, Method: Composition-based stats. Identities = 65/261 (24%), Positives = 115/261 (44%), Gaps = 22/261 (8%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M ++ ++A VTG GIG + + L G +V + + K D++ Sbjct: 9 MVMSQRIAYVTGGMGGIGTSICQRLHKDGFRVVAGC-GPNSPRRVKWLEDQKALGFDFYA 67 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVI 112 + +V D + F KV G +D+LVNNAG+ + ++W+ + NL S+ Sbjct: 68 SEGNVGDWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTREDWQAVIDTNLTSLF 127 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + T +D M ++ G IIN+SS+ G Q Y +K GI GFT S LA + Sbjct: 128 NVTKQVIDGMVERGWGR---IINISSVNGQKGQFGQTNYSTAKAGIHGFTMS--LAQEVA 182 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 GV +N + PG++ T ++++I + + I I + P I + + L Sbjct: 183 TKGVTVNTVSPGYIGTDMVKAIRPD--------VLEKIVATIPVRRLGSPDEIGSIVAWL 234 Query: 233 IEDDALNGAIMKITTSKGIHF 253 +++ + + G+H Sbjct: 235 ASEESGFSTGADFSLNGGLHM 255 >4NBV-A nrPDB Length = 246 Score = 212 bits (539), Expect = 2e-55, Method: Composition-based stats. Identities = 80/261 (30%), Positives = 122/261 (46%), Gaps = 25/261 (9%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M + G+VA++TGAA GIG A A+ GA V L D + A L Sbjct: 1 MKLQGRVAIITGAAAGIGFATAQRFAEDGAIVVLCDVQEARVREAAARLAATGATVSAYR 60 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVI 112 + DV + ++ V+ R+DILVNNAG+ E ++ + +NL V Sbjct: 61 V--DVTRRDEVDAMVAAVLAAHQRVDILVNNAGITKDARLAKMTEAQFDAVIDVNLKGVF 118 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + M++Q G +I+N SS+ GL Q Y ASK G++GFT++ A L Sbjct: 119 NCAQAVAGLMTEQGKG---VILNASSVVGLYGNFGQTNYAASKFGVIGFTKTW--ARELG 173 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 GVR+NA+CPGFVNT IL+++ + D + + +P IA+ L Sbjct: 174 PKGVRVNAVCPGFVNTEILQTVPD--------KVLDGMTSSCWLRRLAEPAEIASIYAFL 225 Query: 233 IEDDA--LNGAIMKITTSKGI 251 DDA +NG ++ + + Sbjct: 226 ASDDASYVNGVAIEASGGMSL 246 >1GEG-A nrPDB Length = 256 Score = 212 bits (539), Expect = 2e-55, Method: Composition-based stats. Identities = 75/257 (29%), Positives = 119/257 (46%), Gaps = 19/257 (7%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 KVALVTGA QGIG+A A L+ G VA+ D+N + +++ + ++ DV Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQA--GGHAVAVKVDV 60 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISGTYL 117 +D+ Q+ + G D++VNNAGV + +K IN+ VI G Sbjct: 61 SDRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWGIQA 120 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 ++ K+ G GG IIN S AG + + VY +SK + G T++A A +L G+ Sbjct: 121 AVEAFKKE--GHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTA--ARDLAPLGIT 176 Query: 178 LNAICPGFVNTAILESIEKE--ENMGQYIEYK-DHIKDMIKYYGILDPPLIANGLITLIE 234 +N CPG V T + I+++ E G+ + Y I + +P +A + L Sbjct: 177 VNGYCPGIVKTPMWAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAACVSYLAS 236 Query: 235 D--DALNGAIMKITTSK 249 D + G + I Sbjct: 237 PDSDYMTGQSLLIDGGM 253 >2ZAT-A nrPDB Length = 260 Score = 208 bits (530), Expect = 2e-54, Method: Composition-based stats. Identities = 66/259 (25%), Positives = 111/259 (42%), Gaps = 24/259 (9%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 + KVALVT + GIG A A L GA V + E + A L Q E Sbjct: 12 LENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATL--QGEGLSVTGTV 69 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN---------NEKNWEKTLQINLVSVIS 113 C V + V+ G +DILV+NA VN E+ W+K L +N+ + + Sbjct: 70 CHVGKAEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKATVL 129 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 T + M K+ GG ++ +SS+ P Y SK ++G T++ LA L Sbjct: 130 MTKAVVPEMEKRG---GGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKN--LAVELAP 184 Query: 174 SGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLI 233 +R+N + PG + T + + ++ K+++K+ ++ + +P A + L Sbjct: 185 RNIRVNCLAPGLIKTNFSQVLWMDKAR------KEYMKESLRIRRLGNPEDCAGIVSFLC 238 Query: 234 EDDA--LNGAIMKITTSKG 250 +DA + G + + Sbjct: 239 SEDASYITGETVVVGGGTA 257 >2CDH-G nrPDB Length = 244 Score = 208 bits (529), Expect = 2e-54, Method: Composition-based stats. Identities = 63/256 (24%), Positives = 113/256 (44%), Gaps = 25/256 (9%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVA 66 V +VTGA++GIG+A A +L G KV + + + E + Q + DV+ Sbjct: 3 VVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKAAEEVSKQIEAYGGQ-AITFGGDVS 61 Query: 67 DQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVISGTYLG 118 + + + +D +G +D++VNNAG+ + W++ + +NL V T Sbjct: 62 KEADVEAMMKTAIDAWGTIDVVVNNAGITRDTLLIRMKKSQWDEVIDLNLTGVFLCTQAA 121 Query: 119 LDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRL 178 M K+ G IIN++S+ GL+ Q Y A+K G++GF+++A A + + + Sbjct: 122 TKIMMKK---RKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTA--AREGASRNINV 176 Query: 179 NAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDA- 237 N +CPGF+ + + + ++ + I I P +A + L A Sbjct: 177 NVVCPGFIASDMTAKLGED--------MEKKILGTIPLGRTGQPENVAGLVEFLALSPAA 228 Query: 238 --LNGAIMKITTSKGI 251 + G I I Sbjct: 229 SYITGQAFTIDGGIAI 244 >5VT6-A nrPDB Length = 269 Score = 207 bits (527), Expect = 4e-54, Method: Composition-based stats. Identities = 64/256 (25%), Positives = 116/256 (45%), Gaps = 23/256 (8%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 +VA VTG G+G A + L G VA+ V + E+ + DV Sbjct: 26 RVAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTW-LMHERDAGRDFKAYAVDV 84 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEK--------NWEKTLQINLVSVISGTYL 117 AD + KV+ FG++D+L+NNAG+ + +W+ ++ +L ++ + T Sbjct: 85 ADFESCERCAEKVLADFGKVDVLINNAGITRDATFMKMTKGDWDAVMRTDLDAMFNVTKQ 144 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 + M ++ G I+N+ S+ G Q Y ++K GI GFT++ LA G+ Sbjct: 145 FIAGMVERRFGR---IVNIGSVNGSRGAFGQANYASAKAGIHGFTKT--LALETAKRGIT 199 Query: 178 LNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDA 237 +N + PG++ TA++E++ ++ + + I + P +A + L DDA Sbjct: 200 VNTVSPGYLATAMVEAVPQDVLEAKILP-------QIPVGRLGRPDEVAALIAFLCSDDA 252 Query: 238 --LNGAIMKITTSKGI 251 + GA + I + Sbjct: 253 GFVTGADLAINGGMHM 268 >5OVL-A nrPDB Length = 300 Score = 207 bits (527), Expect = 4e-54, Method: Composition-based stats. Identities = 64/256 (25%), Positives = 112/256 (43%), Gaps = 36/256 (14%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 + LVTG +GIG A A L G KVA+ P +QCDV Sbjct: 69 RSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGS-------------GAPDDLFGVQCDV 115 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISGTYL 117 D + F++V +H G +++LV NAG++ E+ +E+ + NL Sbjct: 116 TDSAAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQR 175 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 M ++ G II + S++G+ + Q Y A+K G++G RS ++ L +GV Sbjct: 176 ASRTMQRKRFGR---IIFIGSVSGMWGIGNQANYAAAKAGLIGMARS--ISRELAKAGVT 230 Query: 178 LNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDA 237 N + PG+++T + ++++ G D I + +A + L +DA Sbjct: 231 ANVVAPGYIDTEMTRALDERIQAGAL--------DFIPAKRVGTAEEVAGAVSFLASEDA 282 Query: 238 --LNGAIMKITTSKGI 251 + GA++ + G+ Sbjct: 283 SYIAGAVIPVDGGMGM 298 >1X1T-A nrPDB Length = 260 Score = 207 bits (527), Expect = 4e-54, Method: Composition-based stats. Identities = 79/260 (30%), Positives = 126/260 (48%), Gaps = 19/260 (7%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 + GKVA+VTG+ GIG A AL +GA + L + A ++ A K L+ Sbjct: 2 LKGKVAVVTGSTSGIGLGIATALAAQGADIVLNGFGDAAEIEKVRAGLAAQHGVKVLYDG 61 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVISG 114 D++ + +R V GR+DILVNNAG+ + + W+ L +NL +V G Sbjct: 62 ADLSKGEAVRGLVDNAVRQMGRIDILVNNAGIQHTALIEDFPTEKWDAILALNLSAVFHG 121 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 T L +M KQ G IIN++S GL+ A + Y A+KHG+VGFT+ AL Sbjct: 122 TAAALPHMKKQGFGR---IINIASAHGLVASANKSAYVAAKHGVVGFTKVTAL--ETAGQ 176 Query: 175 GVRLNAICPGFVNTAILE----SIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLI 230 G+ NAICPG+V T ++E ++ ++ + Q ++ + + + P + + Sbjct: 177 GITANAICPGWVRTPLVEKQISALAEKNGVDQETAARELLSEKQPSLQFVTPEQLGGTAV 236 Query: 231 TLIEDDA--LNGAIMKITTS 248 L D A + G + + Sbjct: 237 FLASDAAAQITGTTVSVDGG 256 >3UVE-A nrPDB Length = 286 Score = 206 bits (525), Expect = 7e-54, Method: Composition-based stats. Identities = 80/281 (28%), Positives = 120/281 (42%), Gaps = 38/281 (13%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDW---------NLEAGVQCKAALDE- 51 V GKVA VTGAA+G GR+ A L +GA + VD + L E Sbjct: 8 RVEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDLAET 67 Query: 52 ----QFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV---------NNEK 98 + ++ + + DV D L+ V+ GRLDI+V NAG+ +E+ Sbjct: 68 ADLVKGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNGGDTLDKTSEE 127 Query: 99 NWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGI 158 +W + + INL V G+ +M GG GG II SS+ GL Y A+KHG+ Sbjct: 128 DWTEMIDINLAGVWKTVKAGVPHMIA--GGRGGSIILTSSVGGLKAYPHTGHYVAAKHGV 185 Query: 159 VGFTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYG 218 VG R A L +R+N++ P V T +L + E M + DM Sbjct: 186 VGLMR--AFGVELGQHMIRVNSVHPTHVKTPMLHN-EGTFKMFRPDLENPGPDDMAPICQ 242 Query: 219 I--------LDPPLIANGLITLIEDDA--LNGAIMKITTSK 249 + ++P I+N ++ D+A + G + I Sbjct: 243 MFHTLPIPWVEPIDISNAVLFFASDEARYITGVTLPIDAGS 283 >5YSS-A nrPDB Length = 256 Score = 204 bits (520), Expect = 2e-53, Method: Composition-based stats. Identities = 76/261 (29%), Positives = 120/261 (45%), Gaps = 22/261 (8%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M++ GK ALVTG+ GIG A+ L GA + L + + A + + Sbjct: 1 MNLTGKTALVTGSTSGIGLGIAQVLAQAGATLILNGFGDVDAAKDAVAQYGKTPG----Y 56 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVI 112 D++D+ Q+ D R FG +DIL+NNAG+ + W + INL SV Sbjct: 57 HGADLSDEAQIADMMRYAESEFGGVDILINNAGIQHVSPIETFPVDKWNAIIAINLSSVF 116 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 T L L M +N G IIN++S+ GL+ ++ Y A+KHG+VG T++ AL Sbjct: 117 HTTRLALPGMRARNWGR---IINIASVHGLVASKEKSAYVAAKHGVVGLTKTIAL--ETA 171 Query: 173 NSGVRLNAICPGFVNTAIL-ESIEKEENMGQYIEYKDH--IKDMIKYYGILDPPLIANGL 229 + + NA+CPG+V T ++ + I+K G E + + + P + N Sbjct: 172 QTEITCNALCPGWVLTPLVQQQIDKRIAEGAEPEAARDALLAEKQPSREFVTPEQLGNLA 231 Query: 230 ITLIEDDA--LNGAIMKITTS 248 + L D A + G + Sbjct: 232 LFLCSDGAAQVRGVAWNMDGG 252 >3AUT-A nrPDB Length = 269 Score = 204 bits (520), Expect = 3e-53, Method: Composition-based stats. Identities = 69/258 (26%), Positives = 110/258 (42%), Gaps = 21/258 (8%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 + KV ++TG + G+GRA A + AKV + +N E E+ Q + + Sbjct: 12 DLKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQ-AIIV 70 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVIS 113 Q DV ++ + + + + FG LD+++NNAGV N NW K + NL Sbjct: 71 QGDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGAFL 130 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 G+ + Y + G +INMSS+ ++P Y ASK G+ T + LA Sbjct: 131 GSREAIKYFVE--NDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTET--LALEYAP 186 Query: 174 SGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLI 233 G+R+N I PG +NT I E ++ + ++ MI I P +A L Sbjct: 187 KGIRVNNIGPGAMNTPINA-----EKFADPVQ-RADVESMIPMGYIGKPEEVAAVAAFLA 240 Query: 234 EDDA--LNGAIMKITTSK 249 A + G + Sbjct: 241 SSQASYVTGITLFADGGM 258 >4KMS-A nrPDB Length = 249 Score = 204 bits (519), Expect = 3e-53, Method: Composition-based stats. Identities = 64/256 (25%), Positives = 122/256 (47%), Gaps = 30/256 (11%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVA 66 +A+VTG +GIG+A A L KG V N + ++E++ + + +VA Sbjct: 12 IAIVTGGTRGIGKATALELKNKGLTVVA---NFFSNYDAAKEMEEKYGIKTKCW---NVA 65 Query: 67 DQQQLRDTFRKVVDHFGR-LDILVNNAGVNNE--------KNWEKTLQINLVSVISGTYL 117 D ++ R +++ + F + + ILVNNAG+ + ++W + +NL S + + Sbjct: 66 DFEECRQAVKEIEEEFKKPVSILVNNAGITKDKMLHRMSHQDWNDVINVNLNSCFNMSSS 125 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 ++ M Q+ G I+N+SS+ Q Y A+K GI+GFT+ ALA + + Sbjct: 126 VMEQMRNQDYGR---IVNISSINAQAGQVGQTNYSAAKAGIIGFTK--ALARETASKNIT 180 Query: 178 LNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDA 237 +N I PG++ T ++ ++ ++ I + I + P IA + L++++A Sbjct: 181 VNCIAPGYIATEMVGAVPED--------VLAKIINSIPKKRLGQPEEIARAVAFLVDENA 232 Query: 238 --LNGAIMKITTSKGI 251 + G + I + Sbjct: 233 GFITGETISINGGHNM 248 >1GEE-A nrPDB Length = 261 Score = 204 bits (519), Expect = 4e-53, Method: Composition-based stats. Identities = 65/265 (24%), Positives = 117/265 (44%), Gaps = 23/265 (8%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDE-QFEPQKTLF 60 + GKV ++TG++ G+G++ A + AKV + + E + + L+E + + + Sbjct: 4 DLEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKED--EANSVLEEIKKVGGEAIA 61 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVI 112 ++ DV + + + + + FG+LD+++NNAG+ N +W K + NL Sbjct: 62 VKGDVTVESDVINLVQSAIKEFGKLDVMINNAGLENPVSSHEMSLSDWNKVIDTNLTGAF 121 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 G+ + Y + G +INMSS+ +P Y ASK G+ T + LA Sbjct: 122 LGSREAIKYFVE--NDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTET--LALEYA 177 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 G+R+N I PG +NT I + E + ++ MI I +P IA L Sbjct: 178 PKGIRVNNIGPGAINTPINAEKFADP------EQRADVESMIPMGYIGEPEEIAAVAAWL 231 Query: 233 IEDDA--LNGAIMKITTSKGIHFQD 255 +A + G + ++ Sbjct: 232 ASSEASYVTGITLFADGGMTLYPSF 256 >6NRP-A nrPDB Length = 263 Score = 203 bits (518), Expect = 5e-53, Method: Composition-based stats. Identities = 58/253 (22%), Positives = 116/253 (45%), Gaps = 26/253 (10%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 + LVTG+++GIG+A A L G V + + +A + + + Q Q + ++ DV Sbjct: 25 RRILVTGSSRGIGKAIALQLAKAGFDVTVHARSRQAEAE-QVVQEIQALGQNSHYLMFDV 83 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISGTYL 117 ++Q ++ + V+ G +V NAG+ +++W++ + +L + Sbjct: 84 NERQTVQQILEQDVEQHGGFYGVVLNAGLTHDGAFPALTDQDWDEVISTSLDGFYNVLKP 143 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 + M + +GG I+ +SS++G+M Q Y A+K G++G T+ ALA L + Sbjct: 144 LI--MPMIHLRKGGRIVTLSSVSGIMGNRGQVNYSAAKAGLIGATK--ALALELAKRKIT 199 Query: 178 LNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDA 237 +N + PG + T ++ E K+H MI + +A+ + L D+A Sbjct: 200 VNCVAPGLIETEMVTD-----------EVKEHALKMIPLQRMGQVDEVASVVKFLCSDEA 248 Query: 238 --LNGAIMKITTS 248 + ++ + Sbjct: 249 SYVTRQVISVNGG 261 >4IIN-A nrPDB Length = 271 Score = 203 bits (518), Expect = 5e-53, Method: Composition-based stats. Identities = 64/258 (24%), Positives = 106/258 (41%), Gaps = 24/258 (9%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M GK L+TGA++GIG A+ L G KV + + E+ + K Sbjct: 25 MQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEE-KGYKAAV 83 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVI 112 I+ D A + + + +V G L LVNNAGV + +++ + NL S Sbjct: 84 IKFDAASESDFIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLTSAF 143 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 G L MSK G ++N++S+ G Q Y ASK G++ ++S A Sbjct: 144 IGCREALKVMSKSRFG---SVVNVASIIGERGNMGQTNYSASKGGMIAMSKS--FAYEGA 198 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 +R N++ PGF+ T + +++ E K I + +A + L Sbjct: 199 LRNIRFNSVTPGFIETDMNANLKDE--------LKADYVKNIPLNRLGSAKEVAEAVAFL 250 Query: 233 IEDD--ALNGAIMKITTS 248 + D + G +K+ Sbjct: 251 LSDHSSYITGETLKVNGG 268 >3VZS-A nrPDB Length = 257 Score = 203 bits (517), Expect = 6e-53, Method: Composition-based stats. Identities = 64/258 (24%), Positives = 113/258 (43%), Gaps = 22/258 (8%) Query: 4 NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63 ++A VTG GIG A + L G +V + + K ++ + + Sbjct: 13 TQRIAYVTGGMGGIGTAICQRLAKDGFRVVAGC-GPNSPRREKWLEQQKALGFDFIASEG 71 Query: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVISGT 115 +VAD + F KV G +D+L+NNAG+ + +W+ + NL S+ + T Sbjct: 72 NVADWDSTKTAFDKVKSEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNVT 131 Query: 116 YLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSG 175 +D M+ + G I+N+SS+ G Q Y +K G+ GFT ALA + G Sbjct: 132 KQVIDGMADRGWGR---IVNISSVNGQKGQFGQTNYSTAKAGLHGFT--MALAQEVATKG 186 Query: 176 VRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIED 235 V +N + PG++ T ++++I ++ D I I + P IA+ L + Sbjct: 187 VTVNTVSPGYIATDMVKAIRQD--------VLDKIVATIPVKRLGLPEEIASICAWLSSE 238 Query: 236 DALNGAIMKITTSKGIHF 253 ++ + + G+H Sbjct: 239 ESGFSTGADFSLNGGLHM 256 >3V2H-A nrPDB Length = 281 Score = 203 bits (516), Expect = 8e-53, Method: Composition-based stats. Identities = 71/261 (27%), Positives = 117/261 (44%), Gaps = 19/261 (7%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 + K A++TG+ GIG A A L GA + L + ++ L Sbjct: 22 SMMTKTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAGLSSGTVLHH 81 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVIS 113 D+ ++ D V D FG DILVNNAGV + W++ + +NL S Sbjct: 82 PADMTKPSEIADMMAMVADRFGGADILVNNAGVQFVEKIEDFPVEQWDRIIAVNLSSSFH 141 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 + M K+ G IIN++S GL+ + Y A+KHGI+G T++ AL + Sbjct: 142 TIRGAIPPMKKKGWGR---IINIASAHGLVASPFKSAYVAAKHGIMGLTKTVAL--EVAE 196 Query: 174 SGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMI----KYYGILDPPLIANGL 229 SGV +N+ICPG+V T ++E ++ + I + I +++ + +A+ Sbjct: 197 SGVTVNSICPGYVLTPLVEKQIPDQARTRGITEEQVINEVMLKGQPTKKFITVEQVASLA 256 Query: 230 ITLIEDDA--LNGAIMKITTS 248 + L DDA + G + + Sbjct: 257 LYLAGDDAAQITGTHVSMDGG 277 >5OVJ-A nrPDB Length = 256 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 64/256 (25%), Positives = 112/256 (43%), Gaps = 36/256 (14%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 + LVTG +GIG A A L G KVA+ P +QCDV Sbjct: 25 RSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGS-------------GAPDDLFGVQCDV 71 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISGTYL 117 D + F++V +H G +++LV NAG++ E+ +E+ + NL Sbjct: 72 TDSAAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQR 131 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 M ++ G II + S++G+ + Q Y A+K G++G RS ++ L +GV Sbjct: 132 ASRTMQRKRFGR---IIFIGSVSGMWGIGNQANYAAAKAGLIGMARS--ISRELAKAGVT 186 Query: 178 LNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDA 237 N + PG+++T + ++++ G D I + +A + L +DA Sbjct: 187 ANVVAPGYIDTEMTRALDERIQAGAL--------DFIPAKRVGTAEEVAGAVSFLASEDA 238 Query: 238 --LNGAIMKITTSKGI 251 + GA++ + G+ Sbjct: 239 SYIAGAVIPVDGGMGM 254 >2CFC-A nrPDB Length = 250 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 70/256 (27%), Positives = 124/256 (48%), Gaps = 25/256 (9%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 +VA+VTGA+ G G A A L +G +VA +D + E + A K L ++ DV Sbjct: 3 RVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEET-ARTHWHAYADKVLRVRADV 61 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE-----------KNWEKTLQINLVSVISG 114 AD+ + ++ FG +D+LVNNAG+ + ++K + +N+ + G Sbjct: 62 ADEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVRGIFLG 121 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 L +M Q G +I+N++S+A L+ + Y SK ++ T+S +A + S Sbjct: 122 CRAVLPHMLLQGAG---VIVNIASVASLVAFPGRSAYTTSKGAVLQLTKS--VAVDYAGS 176 Query: 175 GVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIE 234 G+R NA+CPG + T + + + E +D + I I +A+ ++ L Sbjct: 177 GIRCNAVCPGMIETPMTQWRLDQP------ELRDQVLARIPQKEIGTAAQVADAVMFLAG 230 Query: 235 DDA--LNGAIMKITTS 248 +DA +NGA + + + Sbjct: 231 EDATYVNGAALVMDGA 246 >2EW8-A nrPDB Length = 249 Score = 201 bits (511), Expect = 3e-52, Method: Composition-based stats. Identities = 72/261 (27%), Positives = 119/261 (45%), Gaps = 25/261 (9%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 + K+A++TG A GIGRA AE ++GA +A+ D +A + ++ L + Sbjct: 4 RLKDKLAVITGGANGIGRAIAERFAVEGADIAIADL----VPAPEAEAAIRNLGRRVLTV 59 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVIS 113 +CDV+ + ++V+ FGR DILVNNAG+ + W+KT +IN+ S Sbjct: 60 KCDVSQPGDVEAFGKQVISTFGRCDILVNNAGIYPLIPFDELTFEQWKKTFEINVDSGFL 119 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 + M + G IIN++S + + Y ++K +GFTR ALA++L Sbjct: 120 MAKAFVPGMKRNGWGR---IINLTSTTYWLKIEAYTHYISTKAANIGFTR--ALASDLGK 174 Query: 174 SGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLI 233 G+ +NAI P V TA E+ + + ++ I + P + L Sbjct: 175 DGITVNAIAPSLVRTATTEA----SALSAMFDVLPNMLQAIP--RLQVPLDLTGAAAFLA 228 Query: 234 EDDA--LNGAIMKITTSKGIH 252 DDA + G + + H Sbjct: 229 SDDASFITGQTLAVDGGMVRH 249 >4DBZ-A nrPDB Length = 281 Score = 200 bits (510), Expect = 4e-52, Method: Composition-based stats. Identities = 74/257 (28%), Positives = 109/257 (42%), Gaps = 18/257 (7%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVA 66 VALVTGA GIG A L +G +V + E L E + CDV Sbjct: 28 VALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREA--GVEADGRTCDVR 85 Query: 67 DQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVISGTYLG 118 ++ VV+ +G +D+LVNNAG ++ W ++ NL V T Sbjct: 86 SVPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELADELWLDVVETNLTGVFRVTKQV 145 Query: 119 LDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRL 178 L G G I+N++S G + Y ASKHG+VGFT+ AL L +G+ + Sbjct: 146 LKAGGMLERGT-GRIVNIASTGGKQGLVHAAPYSASKHGVVGFTK--ALGLELARTGITV 202 Query: 179 NAICPGFVNTAILESIEK---EENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIED 235 NA+CPGFV T + S+ + + E D I + + P +A + LI Sbjct: 203 NAVCPGFVETPMAASVREHYSDIWEVSTEEAFDRITARVPIGRYVQPSEVAEMVAYLIGP 262 Query: 236 D--ALNGAIMKITTSKG 250 A+ + + G Sbjct: 263 GAAAVTAQALNVCGGLG 279 >4RZI-B nrPDB Length = 240 Score = 200 bits (508), Expect = 6e-52, Method: Composition-based stats. Identities = 63/259 (24%), Positives = 113/259 (43%), Gaps = 36/259 (13%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + + KV +VTG +GIG A + L GAKVA D + G + L Sbjct: 4 LGLEDKVIVVTGGNRGIGAAIVKLLQEMGAKVAFTDLATDGG------------NTEALG 51 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVI 112 + +V D + + ++ D G + +V NAG+ + +W+ L +NL V Sbjct: 52 VVANVTDLESMTAAAAEITDKLGPVYGVVANAGITKDNFFPKLTPADWDAVLNVNLKGVA 111 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 ++ M ++ G I+ +SS++G Q Y A+K G++G +S LA Sbjct: 112 YSIKPFIEGMYERKAG---SIVAISSISGERGNVGQTNYSATKAGVIGMMKS--LAREGA 166 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 GVR NA+ PGF++T + +I ++ ++ I I + P IA + L Sbjct: 167 RYGVRANAVAPGFIDTEMTLAIRED--------IREKITKEIPFRRFGKPEEIAWAVAFL 218 Query: 233 IED---DALNGAIMKITTS 248 + + G ++++ + Sbjct: 219 LSPVASSYVTGEVLRVNGA 237 >3WTC-A nrPDB Length = 262 Score = 200 bits (508), Expect = 7e-52, Method: Composition-based stats. Identities = 74/261 (28%), Positives = 114/261 (43%), Gaps = 19/261 (7%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M ++GK+A VTGAAQGIG+A A L GA V L+D + + ++ ++ + Sbjct: 4 MSLSGKIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEAL--GRRAVA 61 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVI 112 + D++++ Q R T G LDI+VNNAG+ EK IN+ V+ Sbjct: 62 LTADISNRDQFRSTLADAAKTLGGLDIMVNNAGICQVKPILDIEPAEIEKIFSINVQGVL 121 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 G ++ G G IIN S+AG Y A+K + T+SA A L Sbjct: 122 WGMQAAATLFKEK--GTKGKIINACSIAGHEGYPLLGAYSATKFAVRALTQSA--AKELA 177 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYK---DHIKDMIKYYGILDPPLIANGL 229 +SG+ +N+ CPG V T + +I+K E + I + +A + Sbjct: 178 SSGITVNSYCPGIVGTDMWVTIDKRMAEITGTEIGATYKKYVEGIALGRVETADDVAGFV 237 Query: 230 ITLIEDDA--LNGAIMKITTS 248 L DA + G + I Sbjct: 238 AYLSSSDADYMTGQSVLIDGG 258 >5OJG-A nrPDB Length = 260 Score = 198 bits (505), Expect = 2e-51, Method: Composition-based stats. Identities = 69/258 (26%), Positives = 112/258 (43%), Gaps = 20/258 (7%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 GKVA+VT A +GIG A AE LL +GA V + N + + L + K I Sbjct: 7 RFEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGL-TKVAGI 65 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN---------NEKNWEKTLQINLVSVI 112 +A + + FG+++ILVNN G+N +++ W+K ++N+ + Sbjct: 66 AGHIASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVKAGF 125 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 T L +++K+ GG II +S + Y +K +VG TR ALA L Sbjct: 126 QMTKLVHPHIAKEG---GGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTR--ALAMGLA 180 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 +R+N I PG + T + + + G+ E + I + P A + L Sbjct: 181 KDNIRVNGIAPGVIKTKMSQVLWD---GGEDAEKELTDIQEIALGRLGVPDDCAGTVAYL 237 Query: 233 IEDD--ALNGAIMKITTS 248 DD + G ++ I Sbjct: 238 ASDDSSYITGEMIIIAGG 255 >4Z9Y-A nrPDB Length = 253 Score = 198 bits (505), Expect = 2e-51, Method: Composition-based stats. Identities = 65/258 (25%), Positives = 109/258 (42%), Gaps = 24/258 (9%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + GKVAL+TG G+G+ A L G + V+ K ++ L Sbjct: 6 FDLQGKVALITGCDTGLGQGMAIGLAQAGCDIVGVNIVEPKDTIEKVTAL----GRRFLS 61 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKN--------WEKTLQINLVSVI 112 + D+++ + K V FG +DILVNNAG+ ++ W+ + +N+ SV Sbjct: 62 LTADMSNVSGHAELVEKAVAEFGHVDILVNNAGIIRREDAIEFSEKNWDDVMNLNIKSVF 121 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + KQ G+GG IIN++S+ + P Y ASK ++G TR +A Sbjct: 122 FMSQTVARQFIKQ--GKGGKIINIASMLSFQGGIRVPSYTASKSAVMGVTR--LMANEWA 177 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 G+ +NAI PG++ T + + +E + I + I P + + L Sbjct: 178 KHGINVNAIAPGYMATNNTQQLRADEERSKEILDR------IPAGRWGLPQDLMGPSVFL 231 Query: 233 IE--DDALNGAIMKITTS 248 D +NG + + Sbjct: 232 ASSASDYINGYTIAVDGG 249 >3T7C-A nrPDB Length = 299 Score = 198 bits (504), Expect = 2e-51, Method: Composition-based stats. Identities = 71/277 (25%), Positives = 117/277 (42%), Gaps = 34/277 (12%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLE----------AGVQCKAALDE 51 V GKVA +TGAA+G GR+ A L +GA + +D + + Sbjct: 25 KVEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETVRQV 84 Query: 52 QFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE---------KNWEK 102 + ++ + Q DV D ++ V GRLDI++ NA + +E K W Sbjct: 85 EALGRRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRMDPKTWRD 144 Query: 103 TLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFT 162 + +NL + + ++ G GG I+ SS+ GL Y ASKHG+ G Sbjct: 145 MIDVNLNGAWITARVAIPHIMA--GKRGGSIVFTSSIGGLRGAENIGNYIASKHGLHGLM 202 Query: 163 RSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDM--------I 214 R+ AL L +R+N +CP V T +L + E M + ++D + Sbjct: 203 RTMAL--ELGPRNIRVNIVCPSSVATPMLLN-EPTYRMFRPDLENPTVEDFQVASRQMHV 259 Query: 215 KYYGILDPPLIANGLITLIEDDA--LNGAIMKITTSK 249 ++P I+N ++ L+ DDA + G + + Sbjct: 260 LPIPYVEPADISNAILFLVSDDARYITGVSLPVDGGA 296 >1AE1-A nrPDB Length = 273 Score = 197 bits (502), Expect = 3e-51, Method: Composition-based stats. Identities = 65/258 (25%), Positives = 106/258 (41%), Gaps = 20/258 (7%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 + G ALVTG ++GIG A E L GA+V N + +C E+ Sbjct: 18 SLKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREK--GLNVEGS 75 Query: 62 QCDVADQQQLRDTFRKVVDHF-GRLDILVNNAGV--------NNEKNWEKTLQINLVSVI 112 CD+ + + + V F G+L+ILVNNAGV EK++ + N + Sbjct: 76 VCDLLSRTERDKLMQTVAHVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFEAAY 135 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + + + G +I +SS+AG + +Y ASK I T+S LA Sbjct: 136 HLSQIAYPLLKASQNG---NVIFLSSIAGFSALPSVSLYSASKGAINQMTKS--LACEWA 190 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 +R+N++ PG + T ++E+ K+ N Q E + I P ++ + L Sbjct: 191 KDNIRVNSVAPGVILTPLVETAIKK-NPHQKEEIDNFIVKT-PMGRAGKPQEVSALIAFL 248 Query: 233 I--EDDALNGAIMKITTS 248 + G I+ Sbjct: 249 CFPAASYITGQIIWADGG 266 >1UZM-A nrPDB Length = 247 Score = 197 bits (502), Expect = 4e-51, Method: Composition-based stats. Identities = 64/256 (25%), Positives = 111/256 (43%), Gaps = 36/256 (14%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 + LVTG +GIG A A+ L G KVA+ P+ ++ DV Sbjct: 16 RSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGS-------------GAPKGLFGVEVDV 62 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISGTYL 117 D + F V +H G +++LV+NAG++ E+ +EK + NL Sbjct: 63 TDSDAVDRAFTAVEEHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQR 122 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 M + G +I + S++GL + Q Y ASK G++G RS +A L + V Sbjct: 123 ASRSMQRNKFGR---MIFIGSVSGLWGIGNQANYAASKAGVIGMARS--IARELSKANVT 177 Query: 178 LNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDA 237 N + PG+++T + ++++ G I + P +A + L +DA Sbjct: 178 ANVVAPGYIDTDMTRALDERIQQGAL--------QFIPAKRVGTPAEVAGVVSFLASEDA 229 Query: 238 --LNGAIMKITTSKGI 251 ++GA++ + G+ Sbjct: 230 SYISGAVIPVDGGMGM 245 >4IS3-A nrPDB Length = 268 Score = 197 bits (501), Expect = 5e-51, Method: Composition-based stats. Identities = 64/259 (24%), Positives = 114/259 (44%), Gaps = 24/259 (9%) Query: 1 MHV-NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTL 59 M++ KV ++TG +GIG A A+ + GAKV++ E A L E + ++ L Sbjct: 20 MNLVQDKVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYPEEEVL 79 Query: 60 FIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSV 111 D+ + + +V +GRLD+++NNAG+ +E+ ++ + IN+ V Sbjct: 80 GFAPDLTSRDAVMAAVGQVAQKYGRLDVMINNAGITSNNVFSRVSEEEFKHIMDINVTGV 139 Query: 112 ISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANL 171 +G + M G +IIN +S+ G+ Y ASK ++G T L + Sbjct: 140 FNGAWCAYQCMKDAKKG---VIINTASVTGIFGSLSGVGYPASKASVIGLTH--GLGREI 194 Query: 172 MNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLIT 231 + +R+ + PG VNT + G E + + +L+P IAN + Sbjct: 195 IRKNIRVVGVAPGVVNTDMTN--------GNPPEIMEGYLKALPMKRMLEPEEIANVYLF 246 Query: 232 LIEDDA--LNGAIMKITTS 248 L D A + + + + Sbjct: 247 LASDLASGITATTVSVDGA 265 >1K2W-A nrPDB Length = 256 Score = 197 bits (500), Expect = 5e-51, Method: Composition-based stats. Identities = 80/264 (30%), Positives = 125/264 (47%), Gaps = 22/264 (8%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M ++GK AL+TG+A+GIGRAFAEA + +GA+VA+ D NLEA A + Sbjct: 1 MRLDGKTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAAEI-----GPAACA 55 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVI 112 I DV DQ + +++D +G +DILVNNA + +++++ IN+ + Sbjct: 56 IALDVTDQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGTL 115 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 M GG GG IINM+S AG A VYCA+K ++ T+SA L NL+ Sbjct: 116 FMMQAVARAMIA--GGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGL--NLI 171 Query: 173 NSGVRLNAICPGFVNTAILESIE---KEENMGQYIEYKDHIKDMIKYYGILDPPLIANGL 229 G+ +NAI PG V+ + ++ + E K + + + + + Sbjct: 172 RHGINVNAIAPGVVDGEHWDGVDAKFADYENLPRGEKKRQVGAAVPFGRMGRAEDLTGMA 231 Query: 230 ITLI--EDDALNGAIMKITTSKGI 251 I L E D + + + Sbjct: 232 IFLATPEADYIVAQTYNVDGGNWM 255 >5B1Y-A nrPDB Length = 270 Score = 197 bits (500), Expect = 5e-51, Method: Composition-based stats. Identities = 69/260 (26%), Positives = 113/260 (43%), Gaps = 23/260 (8%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 H+ ALVTG ++GIGRA +G V + + + A + + + Sbjct: 20 HMETTYALVTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAEEARRLGSPEAYTV 79 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVIS 113 + DV D + + +V + L++LVN AGV + WE+TL++NL V Sbjct: 80 RVDVGDPDSVTEMSSRVGELIPHLNVLVNAAGVLQLGGIEETSISEWEETLRVNLTGVYL 139 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPV-AQQPVYCASKHGIVGFTRSAALAANLM 172 T L L + K I+N++S+AG Y ASK G++G T+ LA L Sbjct: 140 VTKLLLPLLRKAKW---ASIVNVASIAGETGNVVAGVAYSASKAGVIGLTKR--LAVQLA 194 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 G+R+NA+ P FV T + S E ++ I + IL P +A ++ L Sbjct: 195 GYGIRVNAVAPSFVETDMTRSFLDTP------EKRERIASLHPLKIILKPEDVAEAILFL 248 Query: 233 IED---DALNGAIMKITTSK 249 + + G ++ I + Sbjct: 249 ADPRRSRGITGHVLSINAGR 268 >1HXH-A nrPDB Length = 253 Score = 197 bits (500), Expect = 6e-51, Method: Composition-based stats. Identities = 77/244 (31%), Positives = 121/244 (49%), Gaps = 20/244 (8%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 + GKVALVTG A G+G + LL +GAKVA D N AG Q A L E +++F+ Sbjct: 3 RLQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGE-----RSMFV 57 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVIS 113 + DV+ + V G L++LVNNAG+ +++ + L+IN SV Sbjct: 58 RHDVSSEADWTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRLEDFSRLLKINTESVFI 117 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 G G+ M + GG IINM+S++ +P+ Q Y ASK + TR+AAL+ Sbjct: 118 GCQQGIAAMKE----TGGSIINMASVSSWLPIEQYAGYSASKAAVSALTRAAALSCRKQG 173 Query: 174 SGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLI 233 +R+N+I P + T ++++ + G E H + + P IA ++ L Sbjct: 174 YAIRVNSIHPDGIYTPMMQASLPK---GVSKEMVLHDPKLNRAGRAYMPERIAQLVLFLA 230 Query: 234 EDDA 237 D++ Sbjct: 231 SDES 234 >1NFF-A nrPDB Length = 260 Score = 197 bits (500), Expect = 6e-51, Method: Composition-based stats. Identities = 74/277 (26%), Positives = 118/277 (42%), Gaps = 35/277 (12%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 + GKVALV+G A+G+G + A++ +GAKV D E G A L + ++ Sbjct: 4 RLTGKVALVSGGARGMGASHVRAMVAEGAKVVFGDILDEEGKAMAAELADAAR-----YV 58 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVIS 113 DV Q + V FG L +LVNNAG+ W++ L +NL V Sbjct: 59 HLDVTQPAQWKAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLTGVFL 118 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 G + M + G IIN+SS+ GL Y A+K + G T+S AL L Sbjct: 119 GIRAVVKPMKEAGRG---SIINISSIEGLAGTVACHGYTATKFAVRGLTKSTAL--ELGP 173 Query: 174 SGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLI 233 SG+R+N+I PG V T + + + ++ +P ++N ++ L Sbjct: 174 SGIRVNSIHPGLVKTPMTDWVPEDIF-------------QTALGRAAEPVEVSNLVVYLA 220 Query: 234 EDD--ALNGAIMKITTSK--GIHFQDYDTTPFQAKTQ 266 D+ GA + G+ D+ ++ + Sbjct: 221 SDESSYSTGAEFVVDGGTVAGLAHNDFGAVEVSSQPE 257 >3RWB-A nrPDB Length = 247 Score = 196 bits (499), Expect = 8e-51, Method: Composition-based stats. Identities = 76/261 (29%), Positives = 118/261 (45%), Gaps = 26/261 (9%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 + GK ALVTGAAQGIG+A A L GA V + D N E A++ +K I Sbjct: 3 RLAGKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASI-----GKKARAI 57 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVIS 113 D++D ++ F ++ G +DILVNNA + + +W K + +NL Sbjct: 58 AADISDPGSVKALFAEIQALTGGIDILVNNASIVPFVAWDDVDLDHWRKIIDVNLTGTFI 117 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 T G D M + G+ G +I+++S Y A+K G++GFTR ALA L Sbjct: 118 VTRAGTDQM--RAAGKAGRVISIASNTFFAGTPNMAAYVAAKGGVIGFTR--ALATELGK 173 Query: 174 SGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLI 233 + NA+ PG + + +++ E G ++ + G P IA+ + L Sbjct: 174 YNITANAVTPGLIESDGVKASPHNEAFG-------FVEMLQAMKGKGQPEHIADVVSFLA 226 Query: 234 EDDA--LNGAIMKITTSKGIH 252 DDA + G + + H Sbjct: 227 SDDARWITGQTLNVDAGMVRH 247 >2O23-A nrPDB Length = 265 Score = 196 bits (498), Expect = 9e-51, Method: Composition-based stats. Identities = 71/265 (26%), Positives = 120/265 (45%), Gaps = 33/265 (12%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 V G VA++TG A G+G A AE L+ +GA L+D G L +F Sbjct: 9 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL-----GNNCVFA 63 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------------NEKNWEKTLQIN 107 DV ++ ++ FGR+D+ VN AG+ +++++ L +N Sbjct: 64 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 123 Query: 108 LVSVISGTYLGLDYMSKQ---NGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRS 164 L+ + L M + GG+ G+IIN +S+A Q Y ASK GIVG T Sbjct: 124 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT-- 181 Query: 165 AALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKY-YGILDPP 223 +A +L G+R+ I PG T +L S+ + + + + + + + DP Sbjct: 182 LPIARDLAPIGIRVMTIAPGLFGTPLLTSLPE--------KVCNFLASQVPFPSRLGDPA 233 Query: 224 LIANGLITLIEDDALNGAIMKITTS 248 A+ + +IE+ LNG ++++ + Sbjct: 234 EYAHLVQAIIENPFLNGEVIRLDGA 258 >3U5T-A nrPDB Length = 267 Score = 196 bits (498), Expect = 1e-50, Method: Composition-based stats. Identities = 69/254 (27%), Positives = 106/254 (41%), Gaps = 27/254 (10%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 KVA+VTGA++GIG A A L G V + A + A E K L Q DV Sbjct: 28 KVAIVTGASRGIGAAIAARLASDGFTVVINYAGKAAAAEEVAGKIEA-AGGKALTAQADV 86 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVISGTYL 117 +D +R F + FG +D+LVNNAG+ + +++ + +NL + Sbjct: 87 SDPAAVRRLFATAEEAFGGVDVLVNNAGIMPLTTIAETGDAVFDRVIAVNLKGTFNTLRE 146 Query: 118 GLDYMSKQNGGEGGIIINMS-SLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGV 176 + GG IINMS S GL+ +Y A+K G+ T L+ L + Sbjct: 147 AAQRLR-----VGGRIINMSTSQVGLL-HPSYGIYAAAKAGVEAMTH--VLSKELRGRDI 198 Query: 177 RLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDD 236 +NA+ PG T + G+ E +D + + P IA + L D Sbjct: 199 TVNAVAPGPTATDLFLE-------GKSDEVRDRFAKLAPLERLGTPQDIAGAVAFLAGPD 251 Query: 237 A--LNGAIMKITTS 248 +NG +++ Sbjct: 252 GAWVNGQVLRANGG 265 >5U9P-A nrPDB Length = 265 Score = 195 bits (497), Expect = 1e-50, Method: Composition-based stats. Identities = 56/258 (21%), Positives = 101/258 (39%), Gaps = 23/258 (8%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 ++G+ AL+TG+ +GIG A L GA + + D N E A + E Sbjct: 16 FRLDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATL--ARRFRDEGFAADH 73 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVI 112 DVA+ Q+R + G +DILVNNAG+ +W +++NL V Sbjct: 74 AVFDVAEHAQVRAAIDEFEARVGAIDILVNNAGIQRRAPLDAFEPDDWHALMRVNLDGVF 133 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + +M + G+ IIN+ S+ + Y A+K + T+ + A+ Sbjct: 134 NVAQAVARHMIARGHGK---IINICSVQSELARPTIAPYAATKGAVRMLTK--GMCADWA 188 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 G++ N + PG+ T + ++ + ++ + + I L Sbjct: 189 RYGIQANGLAPGYFETELNRALVDDAAFSDWLCKR------TPAGRWGQVDELCGAAIFL 242 Query: 233 IE--DDALNGAIMKITTS 248 D +NG + + Sbjct: 243 ASAASDFVNGQTLFVDGG 260 >2AE2-A nrPDB Length = 260 Score = 195 bits (495), Expect = 2e-50, Method: Composition-based stats. Identities = 61/265 (23%), Positives = 113/265 (42%), Gaps = 21/265 (7%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 ++ G ALVTG ++GIG E L GA V N + C + K Sbjct: 6 NLEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSK--GFKVEAS 63 Query: 62 QCDVADQQQLRDTFRKVVDHF-GRLDILVNNAGV--------NNEKNWEKTLQINLVSVI 112 CD++ + + ++ V +HF G+L+ILVNNAG+ +++ + IN + Sbjct: 64 VCDLSSRSERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINFEAAY 123 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + L ++ E G ++ +SS++G + V + VY A+K + TR LA Sbjct: 124 HLSVLAHPFLKAS---ERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTR--CLAFEWA 178 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 +R+N + PG + T+++E ++ E + + D + +P +A + L Sbjct: 179 KDNIRVNGVGPGVIATSLVEMTIQDPEQK---ENLNKLIDRCALRRMGEPKELAAMVAFL 235 Query: 233 I--EDDALNGAIMKITTSKGIHFQD 255 + G I+ + + Sbjct: 236 CFPAASYVTGQIIYVDGGLMANCGF 260 >1E3W-A nrPDB Length = 261 Score = 195 bits (495), Expect = 2e-50, Method: Composition-based stats. Identities = 66/265 (24%), Positives = 121/265 (45%), Gaps = 33/265 (12%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 V G VA++TG A G+G + A+ L+ +GA L+D G L +F Sbjct: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL-----GGNCIFA 61 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------------NEKNWEKTLQIN 107 +V +++++ + FGR+D+ VN AG+ +++++ + +N Sbjct: 62 PANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVN 121 Query: 108 LVSVISGTYLGLDYMSKQ---NGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRS 164 L+ + L M + GG+ G+IIN +S+A Q Y ASK GIVG T Sbjct: 122 LIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT-- 179 Query: 165 AALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKY-YGILDPP 223 +A +L G+R+ I PG T +L ++ ++ + + + + DP Sbjct: 180 LPIARDLAPIGIRVVTIAPGLFATPLLTTLPD--------TVRNFLASQVPFPSRLGDPA 231 Query: 224 LIANGLITLIEDDALNGAIMKITTS 248 A+ + +IE+ LNG ++++ + Sbjct: 232 EYAHLVQMVIENPFLNGEVIRLDGA 256 >3V2G-A nrPDB Length = 271 Score = 193 bits (492), Expect = 5e-50, Method: Composition-based stats. Identities = 71/262 (27%), Positives = 116/262 (44%), Gaps = 28/262 (10%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + + GK A VTG ++GIG A A+ L L+GA VAL N Q + EQ + + Sbjct: 27 ISLAGKTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQ-AGGRAVA 85 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVI 112 I+ D D + + R+ V+ G LDILVN+AG+ ++++ + +N + Sbjct: 86 IRADNRDAEAIEQAIRETVEALGGLDILVNSAGIWHSAPLEETTVADFDEVMAVNFRAPF 145 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSS-LAGLMPVAQQPVYCASKHGIVGFTRSAALAANL 171 ++ G+GG II + S LA L+P +Y ASK + G T+ LA +L Sbjct: 146 VAIRSASRHL-----GDGGRIITIGSNLAELVPWPGISLYSASKAALAGLTK--GLARDL 198 Query: 172 MNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLIT 231 G+ +N + PG +T + G + E + ++ I +P IA + Sbjct: 199 GPRGITVNIVHPGSTDTDM------NPADGDHAEAQ---RERIATGSYGEPQDIAGLVAW 249 Query: 232 LIEDD--ALNGAIMKITTSKGI 251 L + GA + I Sbjct: 250 LAGPQGKFVTGASLTIDGGANA 271 >4IIV-A nrPDB Length = 267 Score = 193 bits (491), Expect = 6e-50, Method: Composition-based stats. Identities = 64/254 (25%), Positives = 105/254 (41%), Gaps = 24/254 (9%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 + LVTGA++GIGRA A L G + + AG Q + + DV Sbjct: 27 RSVLVTGASKGIGRAIARQLAADGFNIGVHYHRDAAGAQ-ETLNAIVANGGNGRLLSFDV 85 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVISGTYL 117 A+++Q R+ + G +V+NAG+ + +W+ + NL S + Sbjct: 86 ANREQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPALSNDDWDAVIHTNLDSFYNVIQP 145 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 + M +GG II +SS++G+M Q Y A+K GI+G T+ ALA L + Sbjct: 146 CI--MPMIGARQGGRIITLSSVSGVMGNRGQVNYSAAKAGIIGATK--ALAIELAKRKIT 201 Query: 178 LNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIED-- 235 +N I PG ++T ++E E MI + +A L+ D Sbjct: 202 VNCIAPGLIDTGMIEMEES---------ALKEAMSMIPMKRMGQAEEVAGLASYLMSDIA 252 Query: 236 DALNGAIMKITTSK 249 + ++ I Sbjct: 253 GYVTRQVISINGGM 266 >5EJ2-A nrPDB Length = 308 Score = 193 bits (490), Expect = 9e-50, Method: Composition-based stats. Identities = 73/277 (26%), Positives = 120/277 (43%), Gaps = 34/277 (12%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDW-----NLEAGVQCKAALDEQFE-- 54 V GKVA ++GAA+G GR+ A L +GA + +D NL L E + Sbjct: 34 RVAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETADLV 93 Query: 55 ---PQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKN---------WEK 102 ++ + Q DV D + L+ V+ GRLDI+V NAGV + W+ Sbjct: 94 KDLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTDGRKLHKIRDNVWQD 153 Query: 103 TLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFT 162 + INL V G+ ++ +GG GG I+ SS+ G Y A+KHG++G Sbjct: 154 MIDINLTGVWHTVKAGVPHVL--SGGRGGSIVLTSSVGGRKAYPNTGHYIAAKHGVIGLM 211 Query: 163 RSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGI--- 219 R A A L +R+NA+ P V+T ++ + ++ + + D + Sbjct: 212 R--AFAVELGPHMIRVNAVLPTQVSTTMVMN-DQTFRLFRPDLENPGPDDFAPISQMMHT 268 Query: 220 -----LDPPLIANGLITLIEDD--ALNGAIMKITTSK 249 +D I+N ++ L D+ + G + + Sbjct: 269 LPVPWVDASDISNAVLFLASDESRYVTGVSLPVDAGS 305 >3WYE-A nrPDB Length = 256 Score = 192 bits (489), Expect = 1e-49, Method: Composition-based stats. Identities = 70/257 (27%), Positives = 117/257 (45%), Gaps = 19/257 (7%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 KVALVTGA QGIG+A A L+ G VA+ D+N + +++ + ++ DV Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQA--GGHAVAVKVDV 60 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISGTYL 117 +D+ Q+ + G D++VNNAG+ E++ ++ +N+ SV G Sbjct: 61 SDRDQVFAAVEQARKTLGGFDVIVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQA 120 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 ++ K+ G GG IIN +S+A + Y +K + G T++A A +L G+ Sbjct: 121 AVEAFKKE--GHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTA--ARDLAPLGIT 176 Query: 178 LNAICPGFVNTAILESIEKEENMGQYIEYKDHIKD---MIKYYGILDPPLIANGLITLIE 234 +N CPG V T + E I+ E + ++ K+ I P +A + L Sbjct: 177 VNGYCPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLAS 236 Query: 235 D--DALNGAIMKITTSK 249 D + G + I Sbjct: 237 PDSDYMTGQSLLIDGGM 253 >6CI9-A nrPDB Length = 259 Score = 190 bits (482), Expect = 7e-49, Method: Composition-based stats. Identities = 62/259 (23%), Positives = 105/259 (40%), Gaps = 26/259 (10%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 + G+ A+VTG ++GIGR AE G V + N + + A L K + Sbjct: 6 SLEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLS--GTRGKVTAV 63 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVIS 113 + DV D + R T + V G LDI+ NAG+ + E+ L +N + Sbjct: 64 RADVTDPEDARRTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKGTVY 123 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAG-LMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 L ++ G ++ SS+ G + Y ASK +GF R+AA+ L Sbjct: 124 IVQAALQALTASGHGR---VVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAM--ELA 178 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 + +NA+ PG + T L+ + ++ Y D + I + I N + Sbjct: 179 PKKITINAVLPGNIMTEGLDEMGQD--------YLDQMASAIPAGRLGSVADIGNAALFF 230 Query: 233 IEDDA--LNGAIMKITTSK 249 D+A + G + + + Sbjct: 231 ATDEAAYVTGQTLVVDGGQ 249 >1YXM-A nrPDB Length = 303 Score = 189 bits (480), Expect = 1e-48, Method: Composition-based stats. Identities = 64/269 (23%), Positives = 115/269 (42%), Gaps = 25/269 (9%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQK---TL 59 + G+VA+VTG A GIG+A + LL G+ V + LE L P K + Sbjct: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 Query: 60 FIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSV 111 IQC++ +++++ + + +D FG+++ LVNN G + K W L+ NL Sbjct: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 Query: 112 ISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANL 171 K+ GG I+N+ + A++ G+ T+S LA Sbjct: 136 FYMCKAVYSSWMKE---HGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKS--LALEW 189 Query: 172 MNSGVRLNAICPGFVNTAILESIEKEENMGQYIE-YKDHIKDMIKYYGILDPPLIANGLI 230 SG+R+N + PG + S EN G + + + + I I P +++ + Sbjct: 190 ACSGIRINCVAPGVI-----YSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVC 244 Query: 231 TLIEDDA--LNGAIMKITTSKGIHFQDYD 257 L+ A + G + + + ++ Y+ Sbjct: 245 FLLSPAASFITGQSVDVDGGRSLYTHSYE 273 >4E6P-A nrPDB Length = 259 Score = 188 bits (479), Expect = 2e-48, Method: Composition-based stats. Identities = 76/263 (28%), Positives = 119/263 (45%), Gaps = 22/263 (8%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 + GK AL+TG+A+GIGRAFAEA + +GA VA+ D ++E Q A + + Sbjct: 5 RLEGKSALITGSARGIGRAFAEAYVREGATVAIADIDIERARQAAAEI-----GPAAYAV 59 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVIS 113 Q DV Q + V+H G LDILVNNA + +++EK IN+ + Sbjct: 60 QMDVTRQDSIDAAIAATVEHAGGLDILVNNAALFDLAPIVEITRESYEKLFAINVAGTLF 119 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 M Q G GG IINM+S AG A +YCA+K ++ T+SA L +L+ Sbjct: 120 TLQAAARQMIAQ--GRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAGL--DLIK 175 Query: 174 SGVRLNAICPGFVNT---AILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLI 230 + +NAI PG V+ ++++ E K + + + + + + I Sbjct: 176 HRINVNAIAPGVVDGEHWDGVDALFARYENRPRGEKKRLVGEAVPFGRMGTAEDLTGMAI 235 Query: 231 TLIE--DDALNGAIMKITTSKGI 251 L D + + + Sbjct: 236 FLASAESDYIVSQTYNVDGGNWM 258 >3R3S-A nrPDB Length = 294 Score = 188 bits (477), Expect = 3e-48, Method: Composition-based stats. Identities = 58/258 (22%), Positives = 101/258 (39%), Gaps = 24/258 (9%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 + + ALVTG GIGRA A A +GA VA+ E + + +K + + Sbjct: 46 RLKDRKALVTGGDSGIGRAAAIAYAREGADVAINYLPAEEEDAQQVKALIEECGRKAVLL 105 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN---------NEKNWEKTLQINLVSVI 112 D++D+ R K + G LDIL AG + +++T +N+ ++ Sbjct: 106 PGDLSDESFARSLVHKAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQTFAVNVFALF 165 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 T + + K G II SS+ P Y A+K I+ ++R LA + Sbjct: 166 WITQEAIPLLPK-----GASIITTSSIQAYQPSPHLLDYAATKAAILNYSR--GLAKQVA 218 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 G+R+N + PG + TA+ + + GQ + P +A + L Sbjct: 219 EKGIRVNIVAPGPIWTAL------QISGGQTQDKIPQFGQQTPMKRAGQPAELAPVYVYL 272 Query: 233 IEDD--ALNGAIMKITTS 248 + + + + Sbjct: 273 ASQESSYVTAEVHGVCGG 290 >5ILO-A nrPDB Length = 271 Score = 187 bits (475), Expect = 5e-48, Method: Composition-based stats. Identities = 84/249 (33%), Positives = 136/249 (54%), Gaps = 7/249 (2%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGA-KVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 GK A+VTG A GIG ++ LL GA KVA++D L+ ++ L Q + Sbjct: 12 SFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIID--LQDNLEEFVKLRAAHPTQSVMI 69 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLD 120 I+ DVA+++ + T+ ++ FG +DI+VN AG+ N+K+ ++TL +NL +I+ T L Sbjct: 70 IKMDVANKKGVEATYEEIAKTFGNIDIVVNVAGIFNDKDVQRTLLVNLGGIINSTLSALP 129 Query: 121 YMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNA 180 YM K NGG+GGI++NMSS+ GL P+ PVY A+K GI+ FTR A SG++ Sbjct: 130 YMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRSGIKFVT 189 Query: 181 ICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNG 240 +CPG T + + ++ + E D ++ ++ ++ ++E D NG Sbjct: 190 VCPGATMTDMFTNFTEKI---IFPETSDETYRILDRLNKQSAADVSRCILNVLEKDK-NG 245 Query: 241 AIMKITTSK 249 A+ I + Sbjct: 246 AVYVIEGKR 254 >4MOW-A nrPDB Length = 256 Score = 187 bits (474), Expect = 5e-48, Method: Composition-based stats. Identities = 67/257 (26%), Positives = 116/257 (45%), Gaps = 23/257 (8%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 + GKVA+VTGA++GIG A A+AL +GA V + + +AG + + + + + Sbjct: 11 KLAGKVAIVTGASKGIGAAIAKALADEGAAVVVNYASSKAGADAVVSAITE-AGGRAVAV 69 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVIS 113 DV+ + ++ +GRLD+LVNN+GV E+++ + N+ V+ Sbjct: 70 GGDVSKAADAQRIVDTAIETYGRLDVLVNNSGVYEFAPIEAITEEHYRRQFDTNVFGVLL 129 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 T + ++ GEG IIN+SS+ + VY +K + T LA L Sbjct: 130 TTQAAVKHL-----GEGASIINISSVVTSITPPASAVYSGTKGAVDAIT--GVLALELGP 182 Query: 174 SGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLI 233 +R+NAI PG + T S + + + + +P IA+ + L Sbjct: 183 RKIRVNAINPGMIVTEGTHS-----AGIIGSDLEAQVLGQTPLGRLGEPNDIASVAVFLA 237 Query: 234 EDDA--LNGAIMKITTS 248 DDA + G + ++ Sbjct: 238 SDDARWMTGEHLVVSGG 254 >5T5Q-A nrPDB Length = 247 Score = 185 bits (471), Expect = 1e-47, Method: Composition-based stats. Identities = 61/258 (23%), Positives = 102/258 (39%), Gaps = 29/258 (11%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + ++TGA GIGRA AE GA + L D + E A+L P++ Sbjct: 5 FEFENRTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASL---GSPERIAT 61 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVI 112 I+ D + T ++ FG +D LV +AG+ ++ +W +T+ INL V Sbjct: 62 IKADASSADDAEKTVALAMERFGGIDFLVPSAGIYQAKPFAEMSDADWHRTISINLDGVF 121 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 L + + + I+ ++SLA Y A+K +V TR AL+ L Sbjct: 122 YLCKRALPALKEDS-----SIVTLASLAAYRGAYVNAHYGATKGAMVSMTR--ALSRELA 174 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 R+N + PG + T + + K D + P IA+ + L Sbjct: 175 PK-TRVNGVSPGIIETPMTSELLKTRM--------DETMTQTPLKRLGKPSEIASVIAFL 225 Query: 233 IEDDA--LNGAIMKITTS 248 A + G +++ Sbjct: 226 CSPAASFVTGETIQVNGG 243 >3D3W-A nrPDB Length = 244 Score = 183 bits (465), Expect = 6e-47, Method: Composition-based stats. Identities = 58/258 (22%), Positives = 109/258 (42%), Gaps = 30/258 (11%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + + G+ LVTGA +GIGR +AL GA+V V E Sbjct: 3 LFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVR------ECPGIEP 56 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVI 112 + D+ D + V G +D+LVNNA V ++ ++++ ++NL +VI Sbjct: 57 VCVDLGDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVI 112 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + + + + G G I+N+SS V VYC++K + T+ AL L Sbjct: 113 QVSQIVARGLIAR--GVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMAL--ELG 168 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 +R+NA+ P V T++ ++ + + + + + I + + N ++ L Sbjct: 169 PHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNR------IPLGKFAEVEHVVNAILFL 222 Query: 233 IEDDA--LNGAIMKITTS 248 + D + G+ + + Sbjct: 223 LSDRSGMTTGSTLPVEGG 240 >3A28-C nrPDB Length = 258 Score = 183 bits (464), Expect = 9e-47, Method: Composition-based stats. Identities = 67/257 (26%), Positives = 109/257 (42%), Gaps = 17/257 (6%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 KVA+VTG AQGIGR +E L G +A+ D + + + QK +F+ DV Sbjct: 3 KVAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQEEQAAETIKLIEAADQKAVFVGLDV 62 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISGTYL 117 D+ + + G D+LVNNAG+ E++ ++ +N+ SV G Sbjct: 63 TDKANFDSAIDEAAEKLGGFDVLVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQA 122 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 + G G IIN +S+A + Y +K + G T++A A L G Sbjct: 123 ASRKFDEL--GVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAA--AQELAPKGHT 178 Query: 178 LNAICPGFVNTAILESIEKEENMGQYIEYKDHIKD---MIKYYGILDPPLIANGLITLIE 234 +NA PG V T + E I+ E + ++ K+ I P +A + L Sbjct: 179 VNAYAPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLAS 238 Query: 235 D--DALNGAIMKITTSK 249 + + + G +M + Sbjct: 239 ENSNYVTGQVMLVDGGM 255 >4HP8-A nrPDB Length = 247 Score = 182 bits (463), Expect = 1e-46, Method: Composition-based stats. Identities = 67/258 (25%), Positives = 108/258 (41%), Gaps = 29/258 (11%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + G+ ALVTGA G+G+A A L GA+V A D Sbjct: 5 FSLEGRKALVTGANTGLGQAIAVGLAAAGAEVVCAARRAPDETLDIIAKD----GGNASA 60 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVI 112 + D AD +D+F DILVNNAG+ +E +W++ + +NL ++ Sbjct: 61 LLIDFADPLAAKDSFTDA-----GFDILVNNAGIIRRADSVEFSELDWDEVMDVNLKALF 115 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 T + + G G ++N++SL + P Y A+KHG+ G T+ LA Sbjct: 116 FTTQAFAKELLAK--GRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTK--LLANEWA 171 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 G+ +NAI PG++ T E++ + + I + I IA + L Sbjct: 172 AKGINVNAIAPGYIETNNTEALRADAARNKAILER------IPAGRWGHSEDIAGAAVFL 225 Query: 233 IE--DDALNGAIMKITTS 248 D ++GAI+ + Sbjct: 226 SSAAADYVHGAILNVDGG 243 >3ZV3-A nrPDB Length = 281 Score = 182 bits (463), Expect = 1e-46, Method: Composition-based stats. Identities = 63/269 (23%), Positives = 113/269 (42%), Gaps = 30/269 (11%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M + G+VAL+TG A G+GRA + + +GA+VA++D + E + + A + Sbjct: 1 MKLTGEVALITGGASGLGRALVDRFVAEGARVAVLDKSAERLRELEVA-----HGGNAVG 55 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN-------------EKNWEKTLQIN 107 + DV Q + + + FG++D L+ NAG+ + + ++ +N Sbjct: 56 VVGDVRSLQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDIFHVN 115 Query: 108 LVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 + I L + G ++ S AG P P+Y A+KH +VG R + Sbjct: 116 VKGYIHAVKACLPALVSSR----GSVVFTISNAGFYPNGGGPLYTATKHAVVGLVRQ--M 169 Query: 168 AANLMNSGVRLNAICPGFVNTAIL--ESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLI 225 A L VR+N + PG +NT + S+ E + D +K ++ + Sbjct: 170 AFELAPH-VRVNGVAPGGMNTDLRGPSSLGLSEQSISSVPLADMLKSVLPIGRMPALEEY 228 Query: 226 ANGLITLIED-DAL--NGAIMKITTSKGI 251 + D+L GA++ G+ Sbjct: 229 TGAYVFFATRGDSLPATGALLNYDGGMGV 257 >1CYD-A nrPDB Length = 244 Score = 181 bits (459), Expect = 3e-46, Method: Composition-based stats. Identities = 60/262 (22%), Positives = 111/262 (42%), Gaps = 34/262 (12%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 ++ +G ALVTGA +GIGR +AL GAKV V V E Sbjct: 3 LNFSGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAK------ECPGIEP 56 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVI 112 + D+ D D K + G +D+LVNNA + ++ ++++ +NL SV Sbjct: 57 VCVDLGDW----DATEKALGGIGPVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNLRSVF 112 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + + M N G G I+N+SS+ + Y ++K + T+ A+A L Sbjct: 113 QVSQMVARDMI--NRGVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTK--AMAMELG 168 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 +R+N++ P V T + + + + + ++ + ++ + + N ++ L Sbjct: 169 PHKIRVNSVNPTVVLTDMGKKVSADPEFARKLKERHPLRK------FAEVEDVVNSILFL 222 Query: 233 IEDDALNGAIMKITTSKGIHFQ 254 + D + + T+ GI Sbjct: 223 LSDRSAS------TSGGGILVD 238 >4AVY-A nrPDB Length = 242 Score = 180 bits (456), Expect = 8e-46, Method: Composition-based stats. Identities = 65/252 (25%), Positives = 115/252 (45%), Gaps = 32/252 (12%) Query: 5 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64 G+ LVTG + GIG A A GA+V + + + + + + D Sbjct: 11 GQQVLVTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHAPR--------HPRIRREELD 62 Query: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKN------WEKTLQINLVSVISGTYLG 118 + D Q+L+ F + RLD+LVNNAG++ ++ +E+ L++NL + + + L Sbjct: 63 ITDSQRLQRLFEALP----RLDVLVNNAGISRDREEYDLATFERVLRLNLSAAMLASQLA 118 Query: 119 LDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRL 178 +++ GG I+N++S+ A +P Y ASK IV TRS LA +R+ Sbjct: 119 RPLLAQ----RGGSILNIASMYSTFGSADRPAYSASKGAIVQLTRS--LACEYAAERIRV 172 Query: 179 NAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDA- 237 NAI PG+++T + ++ + +E I + P +A+ L A Sbjct: 173 NAIAPGWIDTPLGAGLKAD------VEATRRIMQRTPLARWGEAPEVASAAAFLCGPGAS 226 Query: 238 -LNGAIMKITTS 248 + GA++ + Sbjct: 227 FVTGAVLAVDGG 238 >1DOH-A nrPDB Length = 283 Score = 180 bits (456), Expect = 8e-46, Method: Composition-based stats. Identities = 60/266 (22%), Positives = 107/266 (40%), Gaps = 24/266 (9%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 + GKVALVTGA +GIGR A L +G KV + N + A + + Sbjct: 26 SLEGKVALVTGAGRGIGREMAMELGRRGCKVIVNYANSTESAEEVVA-AIKKNGSDAACV 84 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVIS 113 + +V + + F + V FG+LDI+ +N+GV + +++ IN Sbjct: 85 KANVGVVEDIVRMFEEAVKIFGKLDIVCSNSGVVSFGHVKDVTPEEFDRVFTINTRGQFF 144 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGL-MPVAQQPVYCASKHGIVGFTRSAALAANLM 172 ++ GG +I M S+ G V + VY SK I F R +A ++ Sbjct: 145 VAREAYKHLE-----IGGRLILMGSITGQAKAVPKHAVYSGSKGAIETFAR--CMAIDMA 197 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMI-----KYYGILDPPLIAN 227 + + +N + PG + T + ++ +E + + + + P IA Sbjct: 198 DKKITVNVVAPGGIKTDMYHAVCREYIPNGENLSNEEVDEYAAVQWSPLRRVGLPIDIAR 257 Query: 228 GLITLIEDDA--LNGAIMKITTSKGI 251 + L +D + G ++ I + Sbjct: 258 VVCFLASNDGGWVTGKVIGIDGGACM 283 >2FWM-X nrPDB Length = 250 Score = 179 bits (454), Expect = 1e-45, Method: Composition-based stats. Identities = 69/261 (26%), Positives = 109/261 (41%), Gaps = 29/261 (11%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M +GK VTGA +GIG A A A + GAKV D +A EQ+ Sbjct: 3 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD---------QAFTQEQYP---FAT 50 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVI 112 DVAD Q+ ++++ RLD LVN AG+ +++W++T +N+ Sbjct: 51 EVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAF 110 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + ++ +Q GG I+ ++S A P Y ASK + S L L Sbjct: 111 NLFQQTMNQFRRQ---RGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGL--ELA 165 Query: 173 NSGVRLNAICPGFVNTAILESIE--KEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLI 230 SGVR N + PG +T + ++ + + + + K I I P IAN ++ Sbjct: 166 GSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTIL 225 Query: 231 TLIEDDA--LNGAIMKITTSK 249 L D A + + + Sbjct: 226 FLASDLASHITLQDIVVDGGS 246 >2HSD-A nrPDB Length = 253 Score = 178 bits (453), Expect = 1e-45, Method: Composition-based stats. Identities = 68/257 (26%), Positives = 109/257 (42%), Gaps = 28/257 (10%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 ++GK ++TG A+G+G A + GA+V L D E G L + Sbjct: 2 DLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATAREL-----GDAARYQ 56 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVIS 113 DV ++ + + FG +D LVNNAG++ + + K ++INL V Sbjct: 57 HLDVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVEINLTGVFI 116 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 G + M GG I+N+SS AGLM +A Y ASK G+ G ++ A A L Sbjct: 117 GMKTVIPAMKDAG---GGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLA--AVELGT 171 Query: 174 SGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLI 233 +R+N++ PG T + + G Y + +P IA ++ L+ Sbjct: 172 DRIRVNSVHPGMTYTPMTAETGIRQGEGNYP--------NTPMGRVGEPGEIAGAVVKLL 223 Query: 234 EDD--ALNGAIMKITTS 248 D + GA + + Sbjct: 224 SDTSSYVTGAELAVDGG 240 >1AHH-A nrPDB Length = 255 Score = 178 bits (451), Expect = 3e-45, Method: Composition-based stats. Identities = 63/257 (24%), Positives = 111/257 (43%), Gaps = 23/257 (8%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + ++GK A++TGA GIG+ A GA V + D N +A + + + Sbjct: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQL--GGQAFA 64 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEK-------NWEKTLQINLVSVIS 113 +CD+ +Q+L + G++DILVNNAG K ++ + ++N+ S Sbjct: 65 CRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFH 124 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 + L M K GG+I+ ++S+A Y +SK R+ +A +L Sbjct: 125 LSQLVAPEMEKNG---GGVILTITSMAAENKNINMTSYASSKAAASHLVRN--MAFDLGE 179 Query: 174 SGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLI 233 +R+N I PG + T L+S+ E + + + P IAN + L Sbjct: 180 KNIRVNGIAPGAILTDALKSV-------ITPEIEQKMLQHTPIRRLGQPQDIANAALFLC 232 Query: 234 EDDA--LNGAIMKITTS 248 A ++G I+ ++ Sbjct: 233 SPAASWVSGQILTVSGG 249 >3OIC-A nrPDB Length = 258 Score = 177 bits (449), Expect = 5e-45, Method: Composition-based stats. Identities = 56/258 (21%), Positives = 110/258 (42%), Gaps = 22/258 (8%) Query: 4 NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63 K ALVTG+++G+G+A A L G + + + A E+ K L ++ Sbjct: 3 QNKCALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALETAEEIEKL-GVKVLVVKA 61 Query: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISGT 115 +V ++++ F+++ + FGRLD+ VNNA E +W+ T+ IN +++ Sbjct: 62 NVGQPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELEETHWDWTMNINAKALLFCA 121 Query: 116 YLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSG 175 M K GG I+++SSL + + SK + TR LA L Sbjct: 122 QEAAKLMEKNGGGH---IVSISSLGSIRYLENYTTVGVSKAALEALTRY--LAVELSPKQ 176 Query: 176 VRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIED 235 + +NA+ G ++T L+ E + + + +++ + + + L+ Sbjct: 177 IIVNAVSGGAIDTDALKHFPNRE------DLLEDARQNTPAGRMVEIKDMVDTVEFLVSS 230 Query: 236 --DALNGAIMKITTSKGI 251 D + G + + + + Sbjct: 231 KADMIRGQTIIVDGGRSL 248 >2B4Q-A nrPDB Length = 276 Score = 177 bits (448), Expect = 6e-45, Method: Composition-based stats. Identities = 66/260 (25%), Positives = 108/260 (41%), Gaps = 23/260 (8%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + G++ALVTG ++GIG+ A+ LL GA+V + + EA L Sbjct: 25 FSLAGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLS---AYGDCQA 81 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAG--------VNNEKNWEKTLQINLVSVI 112 I D++ + R + + + RLDILVNNAG WEK +Q+N+ SV Sbjct: 82 IPADLSSEAGARRLAQALGELSARLDILVNNAGTSWGAALESYPVSGWEKVMQLNVTSVF 141 Query: 113 SGTYLGLDYMSKQNGGEG-GIIINMSSLAGLMPVAQQP-VYCASKHGIVGFTRSAALAAN 170 S L + + E +IN+ S+AG+ + +Q Y SK + +R LA Sbjct: 142 SCIQQLLPLLRRSASAENPARVINIGSVAGISAMGEQAYAYGPSKAALHQLSR--MLAKE 199 Query: 171 LMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLI 230 L+ + +N I PG + + I + + + I P +A I Sbjct: 200 LVGEHINVNVIAPGRFPSRMTRHIANDP------QALEADSASIPMGRWGRPEEMAALAI 253 Query: 231 TLIED--DALNGAIMKITTS 248 +L + G ++ I Sbjct: 254 SLAGTAGAYMTGNVIPIDGG 273 >5JS6-A nrPDB Length = 274 Score = 175 bits (445), Expect = 1e-44, Method: Composition-based stats. Identities = 63/254 (24%), Positives = 107/254 (42%), Gaps = 26/254 (10%) Query: 22 AEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVVDH 81 A + GA+V + D + G + L +FI CDV + ++ + + Sbjct: 28 VRAFVNSGARVVICDKDESGGRALEQEL------PGAVFILCDVTQEDDVKTLVSETIRR 81 Query: 82 FGRLDILVNNAG---------VNNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGI 132 FGRLD +VNNAG + + + + L++NL+ + T L L Y+ K G Sbjct: 82 FGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQ----GN 137 Query: 133 IINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILE 192 +IN+SSL G + AQ Y A+K + T+ ALA + GVR+N I PG + T + E Sbjct: 138 VINISSLVGAIGQAQAVPYVATKGAVTAMTK--ALALDESPYGVRVNCISPGNIWTPLWE 195 Query: 193 SIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIED-DALNGAIMKITTSK-- 249 + + + + + P + + L + + G + +T Sbjct: 196 ELAALMPDPRATIREGMLAQ--PLGRMGQPAEVGAAAVFLASEANFCTGIELLVTGGAEL 253 Query: 250 GIHFQDYDTTPFQA 263 G + +TP A Sbjct: 254 GYGCKASRSTPVDA 267 >4RGB-A nrPDB Length = 294 Score = 175 bits (445), Expect = 1e-44, Method: Composition-based stats. Identities = 69/276 (25%), Positives = 128/276 (46%), Gaps = 35/276 (12%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLE----------AGVQCKAALDE 51 ++G+V +TGAA+G GR+ A +GA + VD + + A Sbjct: 22 SLDGRVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEETARLV 81 Query: 52 QFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV----NNEKNWEKTL--- 104 + Q+ LF + DV D+ L++ F V+ FG +D ++ NAGV +E++ + L Sbjct: 82 EKTGQEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLTNPDERDASEALRLG 141 Query: 105 -QINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLM----PVAQQPVYCASKHGIV 159 I L+ V + + + +M ++ G+GG +I SS+ L+ Y SK I Sbjct: 142 LDIMLIGVWNTFQVAIPHMKER--GQGGNLIATSSMIALLDLTDGRGGTDAYLTSKLAIT 199 Query: 160 GFTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMI----K 215 G RS AL L +R+N + P +T + I + + + IE H+ + + Sbjct: 200 GLVRSYALM--LAADRIRVNGVAPTNCSTPM---ITENPALFKVIEENPHLVNAMSTALP 254 Query: 216 YYGILDPPLIANGLITLIED--DALNGAIMKITTSK 249 + +++P ++N ++ LI D + G+++K+ Sbjct: 255 DFPMIEPRDVSNAILFLISDAGRSFTGSVLKVDAGM 290 >4TRR-A nrPDB Length = 269 Score = 175 bits (444), Expect = 2e-44, Method: Composition-based stats. Identities = 71/261 (27%), Positives = 118/261 (45%), Gaps = 20/261 (7%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 ++NGK A+VTGAA GIG+ A L GA VA+ D N + +++ K + + Sbjct: 11 NLNGKTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANAVADEINKA--GGKAIGV 68 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVIS 113 DV +++ + KV + FG +DILV+NAG+ + +W+K I++ Sbjct: 69 AMDVTNEEAVNTGIDKVAEAFGSVDILVSNAGIQIVNPIENYSFADWKKMQAIHVDGAFL 128 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 T L +M K GG++I M S+ + Y +KHG++G R LA Sbjct: 129 TTKAALKHMYKD--DRGGVVIYMGSVHSHEASPLKSAYVTAKHGLLGLAR--VLAKEGAK 184 Query: 174 SGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIK----YYGILDPPLIANGL 229 VR + +CPGFV T +++ E+ I ++ IK ++ +A + Sbjct: 185 HNVRSHVVCPGFVRTPLVDKQIPEQAKELGISEEEVIKKVMLGNTVDGVFTTVQDVAQTV 244 Query: 230 ITLIEDD--ALNGAIMKITTS 248 + L AL G ++ Sbjct: 245 LFLSAFPSAALTGQSFIVSHG 265 >3V8B-A nrPDB Length = 283 Score = 173 bits (439), Expect = 6e-44, Method: Composition-based stats. Identities = 67/264 (25%), Positives = 115/264 (43%), Gaps = 19/264 (7%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M+ VAL+TGA GIGRA A AL G V + + + + + Sbjct: 24 MNQPSPVALITGAGSGIGRATALALAADGVTVGALGRTRTEVEEVADEIV--GAGGQAIA 81 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN---------NEKNWEKTLQINLVSV 111 ++ DV+D+ Q+R+ R +V FG LDI+V NAG+N W++T+ +NL Sbjct: 82 LEADVSDELQMRNAVRDLVLKFGHLDIVVANAGINGVWAPIDDLKPFEWDETIAVNLRGT 141 Query: 112 ISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANL 171 +L + Y+ ++ GG I+ +SS+ G + LA L Sbjct: 142 FLTLHLTVPYLKQRG---GGAIVVVSSINGTRTFTTPGATAYTATKAAQVAIVQQLALEL 198 Query: 172 MNSGVRLNAICPGFVNTAILES--IEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGL 229 +R+NA+CPG + T I ++ + EE +E+ + I +A + Sbjct: 199 GKHHIRVNAVCPGAIETNISDNTKLRHEEETAIPVEW-PKGQVPITDGQPGRSEDVAELI 257 Query: 230 ITLIEDDA--LNGAIMKITTSKGI 251 L+ + A + G+ + I +G+ Sbjct: 258 RFLVSERARHVTGSPVWIDGGQGL 281 >4FC7-A nrPDB Length = 277 Score = 173 bits (438), Expect = 8e-44, Method: Composition-based stats. Identities = 51/261 (19%), Positives = 97/261 (37%), Gaps = 21/261 (8%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 + KVA +TG GIG AE + G + +L + L ++ L + Sbjct: 25 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLA-GATGRRCLPLS 83 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNN--------AGVNNEKNWEKTLQINLVSVISG 114 DV + + + FGR+DIL+N AG + ++ + I+ + Sbjct: 84 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNV 143 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 + + K GG+I+N+++ G A Q ++K + TR LA Sbjct: 144 SRV---LYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRH--LAVEWGPQ 198 Query: 175 GVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIE 234 +R+N++ PG ++ E +G + + IA+ ++ L Sbjct: 199 NIRVNSLAPGPIS-----GTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLAS 253 Query: 235 D--DALNGAIMKITTSKGIHF 253 + GA++ + F Sbjct: 254 PLASYVTGAVLVADGGAWLTF 274 >1BDB-A nrPDB Length = 277 Score = 171 bits (433), Expect = 4e-43, Method: Composition-based stats. Identities = 63/269 (23%), Positives = 107/269 (39%), Gaps = 30/269 (11%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M + G+ L+TG A G+GRA + + +GAKVA++D + E + E L Sbjct: 1 MKLKGEAVLITGGASGLGRALVDRFVAEGAKVAVLDKSAERLAEL-----ETDHGDNVLG 55 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN-------------EKNWEKTLQIN 107 I DV + + + V FG++D L+ NAG+ + + +++ IN Sbjct: 56 IVGDVRSLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHIN 115 Query: 108 LVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 + I L + G +I S AG P P+Y A+KH IVG R L Sbjct: 116 VKGYIHAVKACLPALVASR----GNVIFTISNAGFYPNGGGPLYTAAKHAIVGLVRE--L 169 Query: 168 AANLMNSGVRLNAICPGFVNTAIL--ESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLI 225 A L VR+N + G +N+ + S+ + D +K ++ + + Sbjct: 170 AFELAPY-VRVNGVGSGGINSDLRGPSSLGMGSKAISTVPLADMLKSVLPIGRMPEVEEY 228 Query: 226 ANGLITLIEDD---ALNGAIMKITTSKGI 251 + GA++ G+ Sbjct: 229 TGAYVFFATRGDAAPATGALLNYDGGLGV 257 >3UF0-A nrPDB Length = 273 Score = 166 bits (421), Expect = 8e-42, Method: Composition-based stats. Identities = 63/258 (24%), Positives = 101/258 (39%), Gaps = 25/258 (9%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + G+ A+VTGA GIGRA A GA V D Sbjct: 27 FSLAGRTAVVTGAGSGIGRAIAHGYARAGAHVLAWGRTDGVKEVADEIAD---GGGSAEA 83 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVI 112 + D+AD + + ++ R+D+LVNNAG+ + W + L +NL + Sbjct: 84 VVADLADLEGAANVAEELAATR-RVDVLVNNAGIIARAPAEEVSLGRWREVLTVNLDAAW 142 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + M G I+ ++S+ Y ASKH +VG TR ALA+ Sbjct: 143 VLSRSFGTAMLAHGSGR---IVTIASMLSFQGGRNVAAYAASKHAVVGLTR--ALASEWA 197 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 GV +NA+ PG+V TA ++ ++ I + I P + + L Sbjct: 198 GRGVGVNALAPGYVVTANTAALRADDERAAEITAR------IPAGRWATPEDMVGPAVFL 251 Query: 233 IEDDA--LNGAIMKITTS 248 D A ++G ++ + Sbjct: 252 ASDAASYVHGQVLAVDGG 269 >5O3Z-A nrPDB Length = 263 Score = 166 bits (420), Expect = 1e-41, Method: Composition-based stats. Identities = 62/263 (23%), Positives = 112/263 (42%), Gaps = 19/263 (7%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M + +VA+V G Q +G E L G VA+ D N + ++ ++ + Sbjct: 3 MAME-QVAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTINSRYGAGRAYG 61 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVI 112 + D D+ + R V + FGR D+LV +AGV +++ +LQ+NLV Sbjct: 62 FKVDATDEASVEALARAVDETFGRADLLVYSAGVAKAAPITQFRLTDFDLSLQVNLVGYF 121 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + M + G G II ++S +G + Y A+K G VG T+S LA +L Sbjct: 122 LCSREFSKLMIRD--GIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQS--LALDLA 177 Query: 173 NSGVRLNAICPG-FVNTAILESIEKEENMG---QYIEYKDHIKDMIKYYGILDPPLIANG 228 G+ ++++ G + + + +S+ + E + + D + D + N Sbjct: 178 EYGITVHSLMLGNLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPLKRGCDYQDVLNV 237 Query: 229 LITLIEDDAL--NGAIMKITTSK 249 L+ D A G + +T + Sbjct: 238 LLFYASDKAAYCTGQSINVTGGQ 260 >5IZ4-A nrPDB Length = 271 Score = 165 bits (418), Expect = 2e-41, Method: Composition-based stats. Identities = 59/256 (23%), Positives = 97/256 (37%), Gaps = 20/256 (7%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQF-EPQKTLFIQCDV 65 V ++TG+A GIG A A G VA+ +++ +TL DV Sbjct: 16 VCVITGSASGIGAATALRFAQAGWSVAIGNFDDSTRDAASTVEALCRDAGAQTLIFDADV 75 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNN-----------EKNWEKTLQINLVSVISG 114 R V + R+D L+N AG + +E+ ++NL+ + Sbjct: 76 GKDADCRHAVDMVASRWQRIDALINCAGTTRVIPHNAFDQIDDFEFERVYRVNLIGLYQM 135 Query: 115 TYLGLDYMSKQ-NGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 T + + + + ++N+SSLAGL Y ASK + T S LA NL Sbjct: 136 TRAAVPLLRESASATRSTSVVNVSSLAGLNGTGSSIAYAASKGAVNTLTLS--LARNLAP 193 Query: 174 SGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL- 232 +R+NA+ PG V+ +L + Y + + + P IA L Sbjct: 194 H-IRVNALAPGMVDDGLLLRVLD---AAAYDGVLSRMTESAPLKRVSRPAEIAELAWFLT 249 Query: 233 IEDDALNGAIMKITTS 248 A+ G ++ Sbjct: 250 AHAPAITGQVIAAENG 265 >3GDF-A nrPDB Length = 267 Score = 164 bits (415), Expect = 4e-41, Method: Composition-based stats. Identities = 55/262 (20%), Positives = 100/262 (38%), Gaps = 28/262 (10%) Query: 1 MHVNGKVALVTGAA--QGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKT 58 + + GKV +VTGA+ +G+G A GA VA+ + G + E+ K Sbjct: 16 LSLKGKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKTYGIKA 75 Query: 59 LFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVS 110 +C V + + VV FG++D + NAG + + W +Q++L Sbjct: 76 KAYKCQVDSYESCEKLVKDVVADFGQIDAFIANAGATADSGILDGSVEAWNHVVQVDLNG 135 Query: 111 VISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVA--QQPVYCASKHGIVGFTRSAALA 168 + ++ G ++ +S++G + +Q Y +K G + RS LA Sbjct: 136 TFHCAKAVGHHFKERGTG---SLVITASMSGHIANFPQEQTSYNVAKAGCIHMARS--LA 190 Query: 169 ANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANG 228 R+N+I PG+++T + + + KE + MI + Sbjct: 191 NEW-RDFARVNSISPGYIDTGLSDFVPKETQQLWH--------SMIPMGRDGLAKELKGA 241 Query: 229 LITLIED--DALNGAIMKITTS 248 + D GA + I Sbjct: 242 YVYFASDASTYTTGADLLIDGG 263 >3UN1-A nrPDB Length = 260 Score = 164 bits (415), Expect = 4e-41, Method: Composition-based stats. Identities = 57/261 (21%), Positives = 103/261 (39%), Gaps = 37/261 (14%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M KV ++TGA+QGIG A + +V +++ Sbjct: 24 MRNQQKVVVITGASQGIGAGLVRAYRDRNYRVVATSRSIKPSADP-----------DIHT 72 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVI 112 + D++ + R+ ++ FGR+D LVNNAGV +++++ L +N+ Sbjct: 73 VAGDISKPETADRIVREGIERFGRIDSLVNNAGVFLAKPFVEMTQEDYDHNLGVNVAGFF 132 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCAS--KHGIVGFTRSAALAAN 170 T M KQ G I+++++ P+ P AS K G+ TRS LA Sbjct: 133 HITQRAAAEMLKQGSGH---IVSITTSLVDQPMVGMPSALASLTKGGLNAVTRS--LAME 187 Query: 171 LMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLI 230 SGVR+NA+ PG + T + E + + + + + + ++ Sbjct: 188 FSRSGVRVNAVSPGVIKTPM-----------HPAETHSTLAGLHPVGRMGEIRDVVDAVL 236 Query: 231 TLIEDDALNGAIMKITTSKGI 251 L + G I+ + + Sbjct: 237 YLEHAGFITGEILHVDGGQNA 257 >2X9N-A nrPDB Length = 288 Score = 162 bits (411), Expect = 1e-40, Method: Composition-based stats. Identities = 63/278 (22%), Positives = 102/278 (36%), Gaps = 46/278 (16%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 H+ A+VTGAA+ IGRA A L G +V + N A + + Sbjct: 20 HMEAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVC 79 Query: 62 QCDVAD----QQQLRDTFRKVVDHFGRLDILVNNA------------------GVNNEKN 99 Q D+ + + FGR D+LVNNA G E Sbjct: 80 QADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDNSNGKTVETQ 139 Query: 100 WEKTLQINLVSVISGTYLGLDYMSKQNG------GEGGIIINMSSLAGLMPVAQQPVYCA 153 + + N ++ T + + +Q G I+N+ P +Y Sbjct: 140 VAELIGTNAIAPFLLT---MSFAQRQKGTNPNCTSSNLSIVNLCDAMVDQPCMAFSLYNM 196 Query: 154 SKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDM 213 KH +VG T+SAAL L G+R+N + PG ++L EE ++ + Sbjct: 197 GKHALVGLTQSAAL--ELAPYGIRVNGVAPGV---SLLPVAMGEEEKDKW-------RRK 244 Query: 214 IKYYGI-LDPPLIANGLITLI--EDDALNGAIMKITTS 248 + IA+ +I L+ + G+I+K+ Sbjct: 245 VPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGG 282 >1H5Q-A nrPDB Length = 265 Score = 162 bits (410), Expect = 1e-40, Method: Composition-based stats. Identities = 63/261 (24%), Positives = 110/261 (42%), Gaps = 30/261 (11%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 K +VTG +GIG AF A+ GA VA++ + V+ + ++F KT QCDV Sbjct: 15 KTIIVTGGNRGIGLAFTRAVAAAGANVAVIYRSAADAVEVTEKVGKEF-GVKTKAYQCDV 73 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISGTYL 117 ++ + T +++ G + L+ NAGV+ +++ +N+ V + Sbjct: 74 SNTDIVTKTIQQIDADLGPISGLIANAGVSVVKPATELTHEDFAFVYDVNVFGVFNTCRA 133 Query: 118 GLDYMSKQNGGEGGIIINMSSL-------AGLMPVAQQPVYCASKHGIVGFTRSAALAAN 170 ++ + G I+ SS+ + L Q Y +SK + LAA Sbjct: 134 VAKLWLQKQ--QKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSSKAACSNLVK--GLAAE 189 Query: 171 LMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLI 230 ++G+R+NA+ PG+VNT ++K + +DH I P + I Sbjct: 190 WASAGIRVNALSPGYVNTDQTAHMDK--------KIRDHQASNIPLNRFAQPEEMTGQAI 241 Query: 231 TLIEDDA--LNGAIMKITTSK 249 L+ D A + G I + Sbjct: 242 LLLSDHATYMTGGEYFIDGGQ 262 >1O5I-A nrPDB Length = 249 Score = 162 bits (409), Expect = 2e-40, Method: Composition-based stats. Identities = 54/255 (21%), Positives = 107/255 (41%), Gaps = 33/255 (12%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + + K LV A++GIGRA A+ L +GA+V + N E + + Sbjct: 15 LGIRDKGVLVLAASRGIGRAVADVLSQEGAEVTICARNE-----------ELLKRSGHRY 63 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVI-----SGT 115 + CD+ ++ L F KV + +DILV NAG +++ + I + Sbjct: 64 VVCDL--RKDLDLLFEKVKE----VDILVLNAGGPKAGFFDELTNEDFKEAIDSLFLNMI 117 Query: 116 YLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSG 175 + +Y+ G I+ ++S + + P+ +++ + GF ++ L+ + G Sbjct: 118 KIVRNYLPAMKEKGWGRIVAITSFSVISPIENLYTSNSARMALTGFLKT--LSFEVAPYG 175 Query: 176 VRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIED 235 + +N + PG+ T ++ + EE K ++ I + P IA+ + L + Sbjct: 176 ITVNCVAPGWTETERVKELLSEEK-------KKQVESQIPMRRMAKPEEIASVVAFLCSE 228 Query: 236 DA--LNGAIMKITTS 248 A L G + + Sbjct: 229 KASYLTGQTIVVDGG 243 >4HBG-A nrPDB Length = 286 Score = 161 bits (407), Expect = 4e-40, Method: Composition-based stats. Identities = 68/281 (24%), Positives = 115/281 (40%), Gaps = 59/281 (20%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEA-----------------GVQCKAAL 49 VA+VTGA +GIG+A + L KG ++ E+ QC A+ Sbjct: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 Query: 50 DEQFEPQKTLFIQCD----VADQQQLRDTFRKVVDHFGR---------LDILVNNAGVNN 96 D + P + D D+ L+ + + D + +++L+N AG+ Sbjct: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 Query: 97 E--------KNWEKTLQINLVSVISGTYLGLDYMSKQN------GGEGGI--IINMSSL- 139 E + + +N +S ++ T + + YM K G+ I+N+SS+ Sbjct: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 Query: 140 -AGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVN-TAILESIEKE 197 +G M V VY ASK + FT LAA + +R I PG V T +++++ Sbjct: 186 HSGKMKVPGTSVYSASKAALSRFT--EVLAAEMEPRNIRCFTISPGLVKGTDMIQNLP-- 241 Query: 198 ENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDAL 238 +E K+ ++ I G P IA + +L AL Sbjct: 242 ------VEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTAL 276 >4EGF-A nrPDB Length = 266 Score = 160 bits (406), Expect = 4e-40, Method: Composition-based stats. Identities = 72/258 (27%), Positives = 119/258 (46%), Gaps = 21/258 (8%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + ++GK AL+TGA +GIG A A GA++ L ++ + AL EQF Sbjct: 16 LRLDGKRALITGATKGIGADIARAFAAAGARLVLSGRDVSELDAARRALGEQF-GTDVHT 74 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVI 112 + D+A+ + R+ + FG LD+LVNNAG+ + + ++ T+ +NL + Sbjct: 75 VAIDLAEPDAPAELARRAAEAFGGLDVLVNNAGISHPQPVVDTDPQLFDATIAVNLRAPA 134 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 M GEGG II ++S A L P+ YC SK G+V T+ LA L Sbjct: 135 LLASAVGKAMVA--AGEGGAIITVASAAALAPLPDHYAYCTSKAGLVMATK--VLARELG 190 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 G+R N++CP V T + + + +E + + I P +++ ++ L Sbjct: 191 PHGIRANSVCPTVVLTEMGQRVWGDEAKSAPMIAR------IPLGRFAVPHEVSDAVVWL 244 Query: 233 IEDDA--LNGAIMKITTS 248 D A +NG + + Sbjct: 245 ASDAASMINGVDIPVDGG 262 >3RKU-A nrPDB Length = 287 Score = 160 bits (405), Expect = 7e-40, Method: Composition-based stats. Identities = 63/246 (25%), Positives = 111/246 (45%), Gaps = 25/246 (10%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKG---AKVALVDWNLEAGVQCKAALDEQFEPQKT 58 + K L+TGA+ GIG+A A L K+ L LE + K +D++F K Sbjct: 30 RLAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPNAKV 89 Query: 59 LFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAG--VNNE-------KNWEKTLQINLV 109 Q D+ ++++ + F +DILVNNAG + ++ ++ + N+ Sbjct: 90 HVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQIATEDIQDVFDTNVT 149 Query: 110 SVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAA 169 ++I+ T L +N G+ I+N+ S+AG +YCASK + FT S L Sbjct: 150 ALINITQAVLPIFQAKNSGD---IVNLGSIAGRDAYPTGSIYCASKFAVGAFTDS--LRK 204 Query: 170 NLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGL 229 L+N+ +R+ I PG V T ++ +Y ++ K++ K L +A+ + Sbjct: 205 ELINTKIRVILIAPGLVETEF--------SLVRYRGNEEQAKNVYKDTTPLMADDVADLI 256 Query: 230 ITLIED 235 + Sbjct: 257 VYATSR 262 >1B15-A nrPDB Length = 254 Score = 160 bits (404), Expect = 8e-40, Method: Composition-based stats. Identities = 65/252 (25%), Positives = 109/252 (43%), Gaps = 15/252 (5%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTL 59 M + K + A GIG + L+ + K ++D A L Sbjct: 1 MDLTNKNVIFVAALGGIGLDTSRELVKRNLKNFVILDR--VENPTALAELKAINPKVNIT 58 Query: 60 FIQCDVADQ-QQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLG 118 F DV + + +K+ D +DIL+N AG+ ++ E+T+ IN +++ T Sbjct: 59 FHTYDVTVPVAESKKLLKKIFDQLKTVDILINGAGILDDHQIERTIAINFTGLVNTTTAI 118 Query: 119 LDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN-SGVR 177 LD+ K+ GG GGII N+ S+ G + Q PVY ASK +V FT S A L +GV Sbjct: 119 LDFWDKRKGGPGGIIANICSVTGFNAIHQVPVYSASKAAVVSFTNSLAK---LAPITGVT 175 Query: 178 LNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDA 237 +I PG T ++ + +++ + + +++ + + IE + Sbjct: 176 AYSINPGITRTPLVHT------FNSWLDVEPRVAELLLSHPTQTSEQCGQNFVKAIEANK 229 Query: 238 LNGAIMKITTSK 249 NGAI K+ Sbjct: 230 -NGAIWKLDLGT 240 >3OML-A nrPDB Length = 613 Score = 159 bits (403), Expect = 1e-39, Method: Composition-based stats. Identities = 64/247 (25%), Positives = 98/247 (39%), Gaps = 35/247 (14%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVD----WNLEAGVQCKAALDEQFEPQ 56 + +G+VA+VTGA G+GR +A +GAKV + D + + Q A + + Sbjct: 15 LRYDGRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRK 74 Query: 57 KTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINL 108 D + FGR+DILVNNAG+ +E++W ++L Sbjct: 75 AGGEAVADYNSVIDGAKVIETAIKAFGRVDILVNNAGILRDRSLVKTSEQDWNLVNDVHL 134 Query: 109 VSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALA 168 T YM KQN G II SS +G+ Q Y A+K G++G + +A Sbjct: 135 KGSFKCTQAAFPYMKKQNYGR---IIMTSSNSGIYGNFGQVNYTAAKMGLIGLANT--VA 189 Query: 169 ANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANG 228 + V N I P + + E I + + L P LIA Sbjct: 190 IEGARNNVLCNVIVPTA-ASRMTEGILPDILFNE-----------------LKPKLIAPV 231 Query: 229 LITLIED 235 + L + Sbjct: 232 VAYLCHE 238 >3PXX-A nrPDB Length = 287 Score = 158 bits (400), Expect = 2e-39, Method: Composition-based stats. Identities = 71/288 (24%), Positives = 115/288 (39%), Gaps = 43/288 (14%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLE----------AGVQCKAALDE 51 V KV LVTG A+G GR+ A L +GA + L D + + +A L+ Sbjct: 7 RVQDKVVLVTGGARGQGRSHAVKLAEEGADIILFDICHDIETNEYPLATSRDLEEAGLEV 66 Query: 52 QFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE------KNWEKTLQ 105 + +K + DV D+ + V FG+LD++V NAG+ + + Sbjct: 67 EKTGRKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANAGICPLGAHLPVQAFADAFD 126 Query: 106 INLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPV-----------YCAS 154 ++ V VI+ + L Y++ G II S+AGL+ AQ P Y + Sbjct: 127 VDFVGVINTVHAALPYLT-----SGASIITTGSVAGLIAAAQPPGAGGPQGPGGAGYSYA 181 Query: 155 KHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMI 214 K + +T LAA L +R N I P VNT +L S +E ++ Sbjct: 182 KQLVDSYT--LQLAAQLAPQSIRANVIHPTNVNTDMLNSAPMYRQFRPDLEAPSRADALL 239 Query: 215 KYY-------GILDPPLIANGLITLIEDD--ALNGAIMKITTSKGIHF 253 + ++ I+N + L D+ + G K+ + F Sbjct: 240 AFPAMQAMPTPYVEASDISNAVCFLASDESRYVTGLQFKVDAGAMLKF 287 >5JY1-A nrPDB Length = 274 Score = 158 bits (399), Expect = 3e-39, Method: Composition-based stats. Identities = 71/267 (26%), Positives = 113/267 (42%), Gaps = 21/267 (7%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 + +VALVTGA GIGR A + +GA V + + N G Q + + E ++LF++ Sbjct: 12 LEQRVALVTGAGGGIGRGVARSFGNEGAAVIIAEINESTGRQVEQEIREM--GGRSLFVK 69 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN-----EKNWEKTLQINLVSVISGTYL 117 DV + + R V+ FG LDILVNNA V E+ ++ L+ L + + T+ Sbjct: 70 TDVTSKASIEAAVRSAVEQFGSLDILVNNAFVPTPNVLLEEKTDEMLEQTLTTSLWATWW 129 Query: 118 GLD-YMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGV 176 + G I+N S+ Y +K GIVG TRSA A+ + Sbjct: 130 AMRAAFVPMRERRWGRIVNFYSIDTETGAWLHGDYNTAKAGIVGLTRSA--ASEWGRFNI 187 Query: 177 RLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPP-LIANGLITLIED 235 +NAI P TA+ + E + E+ + DP I + + Sbjct: 188 TVNAIAP----TAMGATF--FELAAKNPEFAERSAAARPLGRSGDPEQDIGPAAVFFASE 241 Query: 236 --DALNGAIMKITTSKGIHFQDYDTTP 260 + G + + G+H Y++ P Sbjct: 242 MSRFVTGETLHVDG--GLHLPGYNSRP 266 >4CR6-A nrPDB Length = 271 Score = 156 bits (396), Expect = 6e-39, Method: Composition-based stats. Identities = 66/264 (25%), Positives = 106/264 (40%), Gaps = 29/264 (10%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 + GK A+VTGAA GIGRA EA L +GA V +D ++E + I Sbjct: 12 RLAGKAAIVTGAAGGIGRATVEAYLREGASVVAMDL-------APRLAATRYEEPGAIPI 64 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV---------NNEKNWEKTLQINLVSVI 112 CD+AD+ + V G LDILV + ++ +W++ + +N+ Sbjct: 65 ACDLADRAAIDAAMADAVARLGGLDILVAGGALKGGTGNFLDLSDADWDRYVDVNMTGTF 124 Query: 113 SGTYLGLDYMSKQNGGEGG---IIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAA 169 G M G+ G II + S+ M + Y A+K G+ TR A+A Sbjct: 125 LTCRAGARAMVAAGAGKDGRSARIITIGSVNSFMAEPEAAAYVAAKGGVAMLTR--AMAV 182 Query: 170 NLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGL 229 +L G+ +N I PG V+ + + + D + P +A Sbjct: 183 DLARHGILVNMIAPGPVD------VTGNNTGYSEPRLAEQVLDEVALGRPGLPEEVATAA 236 Query: 230 ITLIEDDA--LNGAIMKITTSKGI 251 + L ED + + G+ + I Sbjct: 237 VFLAEDGSSFITGSTITIDGGLSA 260 >2AG5-A nrPDB Length = 246 Score = 156 bits (395), Expect = 8e-39, Method: Composition-based stats. Identities = 75/258 (29%), Positives = 118/258 (45%), Gaps = 29/258 (11%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 ++GKV ++T AAQGIG+A A A +GAKV D N + + Q Sbjct: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTR------- 55 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVIS 113 DV ++Q+ +V RLD+L N AG + EK+W+ ++ +N+ S+ Sbjct: 56 VLDVTKKKQIDQFANEVE----RLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYL 111 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLA-GLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 L M Q G IINMSS+A + V + VY +K ++G T+S +AA+ + Sbjct: 112 MIKAFLPKMLAQK---SGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKS--VAADFI 166 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 G+R N +CPG V+T L+ E+ + G E ++ K IA + L Sbjct: 167 QQGIRCNCVCPGTVDTPSLQ--ERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYL 224 Query: 233 IEDD--ALNGAIMKITTS 248 D+ + G + I Sbjct: 225 ASDESAYVTGNPVIIDGG 242 >3PPI-A nrPDB Length = 281 Score = 156 bits (395), Expect = 9e-39, Method: Composition-based stats. Identities = 62/265 (23%), Positives = 107/265 (40%), Gaps = 32/265 (12%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 G A+V+G A G+G A L G V + D E G L + F+ Sbjct: 27 QFEGASAIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADEL-----GNRAEFV 81 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAG--------VNNEK------NWEKTLQIN 107 +V + + + GRL V G V + + KT+ + Sbjct: 82 STNVTSEDSVLAAIEAA-NQLGRLRYAVVAHGGFGVAQRIVQRDGSPADMGGFTKTIDLY 140 Query: 108 LVSVISGTYLG---LDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRS 164 L + L + + GE G ++ +S+AG Q Y A+K G++G T Sbjct: 141 LNGTYNVARLVAASIAAAEPRENGERGALVLTASIAGYEGQIGQTAYAAAKAGVIGLT-- 198 Query: 165 AALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPL 224 A A +L ++G+R+N I PG + T I+ES+ EE + ++ K + P Sbjct: 199 IAAARDLSSAGIRVNTIAPGTMKTPIMESV-GEEALAKFAANIPFPK------RLGTPDE 251 Query: 225 IANGLITLIEDDALNGAIMKITTSK 249 A+ L+ + +NG +M++ ++ Sbjct: 252 FADAAAFLLTNGYINGEVMRLDGAQ 276 >2NWQ-A nrPDB Length = 272 Score = 152 bits (384), Expect = 2e-37, Method: Composition-based stats. Identities = 52/238 (21%), Positives = 91/238 (38%), Gaps = 24/238 (10%) Query: 9 LVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQ 68 +TGA G G A A G + L E + +A E + L + DV D+ Sbjct: 25 FITGATSGFGEACARRFAEAGWSLVLTGRREE---RLQALAGELSAKTRVLPLTLDVRDR 81 Query: 69 QQLRDTFRKVVDHFGRLDILVNNAGV---------NNEKNWEKTLQINLVSVISGTYLGL 119 + + + F L L+NNAG+ + +W+ + N+ ++ T L L Sbjct: 82 AAMSAAVDNLPEEFATLRGLINNAGLALGTDPAQSCDLDDWDTMVDTNIKGLLYSTRLLL 141 Query: 120 DYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLN 179 + G G I+N+ S+AG P VY +K + F S L +L +GVR+ Sbjct: 142 PRLIAH--GAGASIVNLGSVAGKWPYPGSHVYGGTKAFVEQF--SLNLRCDLQGTGVRVT 197 Query: 180 AICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDA 237 + PG + ++ ++ + + P IA + ++ A Sbjct: 198 NLEPGLCESEF--------SLVRFGGDQARYDKTYAGAHPIQPEDIAETIFWIMNQPA 247 >4HWK-A nrPDB Length = 288 Score = 151 bits (381), Expect = 3e-37, Method: Composition-based stats. Identities = 61/270 (22%), Positives = 112/270 (41%), Gaps = 37/270 (13%) Query: 7 VALVTGAAQGIGR---AFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63 V L+TGA++G GR +LL G+ + L N EA Q +A L + + + + Sbjct: 36 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 95 Query: 64 DVADQQQLRDTFRKVVDH-----FGRLDILVNNAG-----------VNNEKNWEKTLQIN 107 D+ + L+ + + RL +L+NNAG +++ +N Sbjct: 96 DLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 154 Query: 108 LVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 L S++ T L + G ++N+SSL L P +YCA K + AL Sbjct: 155 LTSMLCLTSSVLKAFP-DSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLAL 213 Query: 168 AANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIAN 227 VR+ PG ++T + + + +E ++ + + ++++ ++D + A Sbjct: 214 E----EPNVRVLNYAPGPLDTDM-QQLARETSVDP--DMRKGLQELKAKGKLVDCKVSAQ 266 Query: 228 GLITLIEDDALNGAIMKITTSKGIHFQDYD 257 L++L+E D G H YD Sbjct: 267 KLLSLLEKDEFK---------SGAHVDFYD 287 >4Z3K-A nrPDB Length = 275 Score = 151 bits (381), Expect = 3e-37, Method: Composition-based stats. Identities = 61/270 (22%), Positives = 112/270 (41%), Gaps = 37/270 (13%) Query: 7 VALVTGAAQGIGR---AFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63 V L+TGA++G GR +LL G+ + L N EA Q +A L + + + + Sbjct: 23 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 82 Query: 64 DVADQQQLRDTFRKVVDH-----FGRLDILVNNAG-----------VNNEKNWEKTLQIN 107 D+ + L+ + + RL +L+NNAG +++ +N Sbjct: 83 DLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 141 Query: 108 LVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 L S++ T L + G ++N+SSL L P +YCA K + AL Sbjct: 142 LTSMLCLTSSVLKAFP-DSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLAL 200 Query: 168 AANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIAN 227 VR+ PG ++T + + + +E ++ + + ++++ ++D + A Sbjct: 201 E----EPNVRVLNYAPGPLDTDM-QQLARETSVDP--DMRKGLQELKAKGKLVDCKVSAQ 253 Query: 228 GLITLIEDDALNGAIMKITTSKGIHFQDYD 257 L++L+E D G H YD Sbjct: 254 KLLSLLEKDEFK---------SGAHVDFYD 274 >2P91-A nrPDB Length = 285 Score = 150 bits (378), Expect = 9e-37, Method: Composition-based stats. Identities = 54/262 (20%), Positives = 108/262 (41%), Gaps = 31/262 (11%) Query: 3 VNGKVALVTGAA--QGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + GK AL+TG A + I A++ +GA++A + + + L Sbjct: 19 LEGKRALITGVANERSIAYGIAKSFHREGAQLAFTYATPKLEKRVREIAK---GFGSDLV 75 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNN----------AGV--NNEKNWEKTLQINL 108 ++CDV+ + +++ + + +++G LDI+V++ GV + + ++ + I++ Sbjct: 76 VKCDVSLDEDIKNLKKFLEENWGSLDIIVHSIAYAPKEEFKGGVIDTSREGFKIAMDISV 135 Query: 109 VSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALA 168 S+I+ T L M G G I+ +S V V +K + R LA Sbjct: 136 YSLIALTRELLPLME----GRNGAIVTLSYYGAEKVVPHYNVMGIAKAALESTVRY--LA 189 Query: 169 ANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANG 228 ++ G R+NAI G V T SI + +H + + + + + Sbjct: 190 YDIAKHGHRINAISAGPVKTLAAYSITG------FHLLMEHTTKVNPFGKPITIEDVGDT 243 Query: 229 LITLIED--DALNGAIMKITTS 248 + L D A+ G ++ + Sbjct: 244 AVFLCSDWARAITGEVVHVDNG 265 >4DA9-A nrPDB Length = 280 Score = 149 bits (377), Expect = 1e-36, Method: Composition-based stats. Identities = 64/257 (24%), Positives = 112/257 (43%), Gaps = 22/257 (8%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVA 66 VA+VTG +GIG A AL G +A+ GV + + +F++ D+A Sbjct: 31 VAIVTGGRRGIGLGIARALAASGFDIAITGIGDAEGV-APVIAELSGLGARVIFLRADLA 89 Query: 67 DQQQLRDTFRKVVDHFGRLDILVNNAGVNN----------EKNWEKTLQINLVSVISGTY 116 D + T VV FGR+D LVNNAG+ + +N++ + +NL + T Sbjct: 90 DLSSHQATVDAVVAEFGRIDCLVNNAGIASIVRDDFLDLKPENFDTIVGVNLRGTVFFTQ 149 Query: 117 LGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGV 176 L M + IIN++S++ +M ++ YC SK G+ F S LA L +G+ Sbjct: 150 AVLKAMLASDARASRSIINITSVSAVMTSPERLDYCMSKAGLAAF--SQGLALRLAETGI 207 Query: 177 RLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIED- 235 + + PG + + + ++ G+Y + ++ +P I N + L Sbjct: 208 AVFEVRPGIIRSDMTAAVS-----GKYDGLIE--SGLVPMRRWGEPEDIGNIVAGLAGGQ 260 Query: 236 -DALNGAIMKITTSKGI 251 G++++ I Sbjct: 261 FGFATGSVIQADGGLSI 277 >2BGM-A nrPDB Length = 278 Score = 149 bits (377), Expect = 1e-36, Method: Composition-based stats. Identities = 51/240 (21%), Positives = 97/240 (40%), Gaps = 24/240 (10%) Query: 22 AEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVVDH 81 A+ + GAKV + D + G + + P F+ CDV + +R+ + Sbjct: 33 AKLFVRYGAKVVIADIADDHG---QKVCNNIGSPDVISFVHCDVTKDEDVRNLVDTTIAK 89 Query: 82 FGRLDILVNNAGVNN----------EKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGG 131 G+LDI+ N GV + +++++ + IN+ M G Sbjct: 90 HGKLDIMFGNVGVLSTTPYSILEAGNEDFKRVMDINVYGAFLVAKHAARVMIPAKKG--- 146 Query: 132 IIINMSSLAGLMPVAQQP-VYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAI 190 I+ +S++ VY A+KH ++G T S L L G+R+N + P V + + Sbjct: 147 SIVFTASISSFTAGEGVSHVYTATKHAVLGLTTS--LCTELGEYGIRVNCVSPYIVASPL 204 Query: 191 LESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDD--ALNGAIMKITTS 248 L + ++ +E H +K +L +A+ + L D+ ++G + I Sbjct: 205 LTDVFGVDS--SRVEELAHQAANLK-GTLLRAEDVADAVAYLAGDESKYVSGLNLVIDGG 261 >1P33-A nrPDB Length = 289 Score = 149 bits (376), Expect = 2e-36, Method: Composition-based stats. Identities = 61/290 (21%), Positives = 106/290 (36%), Gaps = 57/290 (19%) Query: 4 NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63 VALVTGAA+ +G + AEAL +G V L A AA P + +Q Sbjct: 6 TAPVALVTGAAKRLGSSIAEALHAEGYTVCLHYHRSAADASTLAATLNARRPNSAITVQA 65 Query: 64 DVADQQQ-----------------LRDTFRKVVDHFGRLDILVNNA-------------- 92 D+++ H+GR D+LVNNA Sbjct: 66 DLSNVATASFSETDGSVPVTLFSRCSALVDACYMHWGRCDVLVNNASSFYPTPLLRKDAG 125 Query: 93 -GVNNEKNWEKTLQINLVSVISGTYLGLDYMSK-----------QNGGEGGIIINMSSLA 140 G ++ + +++L++ + + ++ K + G I+NM Sbjct: 126 EGGSSVGD-KESLEVAAADLFGSNAIAPYFLIKAFAQRVADTRAEQRGTSYSIVNMVDAM 184 Query: 141 GLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENM 200 P+ +Y +K + G TRSAAL L + +R+N + PG L + + Sbjct: 185 TSQPLLGYTMYTMAKEALEGLTRSAAL--ELASLQIRVNGVSPG------LSVLPDDMPF 236 Query: 201 GQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDA--LNGAIMKITTS 248 +Y+ + Y +++ +I L A + G +K+ Sbjct: 237 SVQEDYRRKVP---LYQRNSSAEEVSDVVIFLCSPKAKYITGTCIKVDGG 283 >1OAA-A nrPDB Length = 259 Score = 146 bits (368), Expect = 1e-35, Method: Composition-based stats. Identities = 61/270 (22%), Positives = 107/270 (39%), Gaps = 37/270 (13%) Query: 7 VALVTGAAQGIGRAFAEALLLK---GAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63 V ++TGA++G GRA A L G+ + + + Q K L Q K + Sbjct: 8 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAA 67 Query: 64 DVADQQQLRDTFRKVVDH-----FGRLDILVNNAG-----------VNNEKNWEKTLQIN 107 D+ + ++ V + RL +L+NNA VN+ +N Sbjct: 68 DLGTEAGVQRLLSAVRELPRPEGLQRL-LLINNAATLGDVSKGFLNVNDLAEVNNYWALN 126 Query: 108 LVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 L S++ T L+ + + G ++N+SSL L P +YCA K L Sbjct: 127 LTSMLCLTSGTLNAF-QDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDML--YQVL 183 Query: 168 AANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIAN 227 AA VR+ + PG ++ + + + +E + + E + ++ + ++D A Sbjct: 184 AAE--EPSVRVLSYAPGPLDNDM-QQLARETS--KDPELRSKLQKLKSDGALVDCGTSAQ 238 Query: 228 GLITLIEDDALNGAIMKITTSKGIHFQDYD 257 L+ L++ D T G H YD Sbjct: 239 KLLGLLQKD---------TFQSGAHVDFYD 259 >5PGZ-A nrPDB Length = 276 Score = 144 bits (364), Expect = 3e-35, Method: Composition-based stats. Identities = 48/195 (24%), Positives = 77/195 (39%), Gaps = 13/195 (6%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 + GK +VTGA++GIGR A L GA V L + E G+Q + + +I Sbjct: 16 LQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEE-GLQKVVSRCLELGAASAHYIA 74 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVISG 114 + D K G LD+L+ N + + +++N +S + Sbjct: 75 GTMEDMTFAEQFIVKAGKLMGGLDMLILNHITQTSLSLFHDDIHSVRRVMEVNFLSYVVM 134 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 + L + + N G I +SSLAG M Y ASK + GF + + Sbjct: 135 STAALPMLKQSN----GSIAVISSLAGKMTQPMIAPYSASKFALDGFFSTIRTELYITKV 190 Query: 175 GVRLNAICPGFVNTA 189 V + G ++T Sbjct: 191 NVSITLCVLGLIDTE 205 >2QHX-A nrPDB Length = 328 Score = 143 bits (362), Expect = 6e-35, Method: Composition-based stats. Identities = 59/286 (20%), Positives = 104/286 (36%), Gaps = 55/286 (19%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVA 66 VALVTGAA+ +GR+ AE L +G V L A +A P + +Q D++ Sbjct: 48 VALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLS 107 Query: 67 DQQQ-----------------LRDTFRKVVDHFGRLDILVNNAGVN-------NEKN--- 99 + + H+GR D+LVNNA N+++ Sbjct: 108 NVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHE 167 Query: 100 ----WEKTLQINLVSVISGTYLGLDYMSKQNG-----------GEGGIIINMSSLAGLMP 144 + ++ + + ++ K G IINM P Sbjct: 168 PCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQP 227 Query: 145 VAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYI 204 + +Y +K + G TRSAAL L +R+N + PG + +++ + Sbjct: 228 LLGYTIYTMAKGALEGLTRSAAL--ELAPLQIRVNGVGPGL--SVLVDDMP-------PA 276 Query: 205 EYKDHIKDMIKYYGILDPPLIANGLITLIEDDA--LNGAIMKITTS 248 ++ H + Y +++ +I L A + G +K+ Sbjct: 277 VWEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGG 322 >4GKB-A nrPDB Length = 258 Score = 143 bits (361), Expect = 7e-35, Method: Composition-based stats. Identities = 65/258 (25%), Positives = 105/258 (40%), Gaps = 21/258 (8%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 +++ KV +VTG A GIG A + L + A + + G A Q + + Sbjct: 3 LNLQDKVVIVTGGASGIGGAISMRLAEERAIPVVFARHAPDGAFLDALAQRQ---PRATY 59 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN-------EKNWEKTLQINLVSVIS 113 + ++ D Q RD + + FGRLD LVNNAGVN+ + +L+ NL+ + Sbjct: 60 LPVELQDDAQCRDAVAQTIATFGRLDGLVNNAGVNDGIGLDAGRDAFVASLERNLIHYYA 119 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 + + ++ G I+N+SS + YCASK + TR A+A L Sbjct: 120 MAHYCVPHLKATR----GAIVNISSKTAVTGQGNTSGYCASKGAQLALTREWAVA--LRE 173 Query: 174 SGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYY-GILDPPLIANGLITL 232 GVR+NA+ P V T + + I + P IA+ + L Sbjct: 174 HGVRVNAVIPAEVMTPLYRNWIA--TFEDPEAKLAEIAAKVPLGRRFTTPDEIADTAVFL 231 Query: 233 IEDDA--LNGAIMKITTS 248 + A G + + Sbjct: 232 LSPRASHTTGEWLFVDGG 249 >2YW9-A nrPDB Length = 261 Score = 143 bits (361), Expect = 7e-35, Method: Composition-based stats. Identities = 61/263 (23%), Positives = 98/263 (37%), Gaps = 32/263 (12%) Query: 2 HVNGKVALVTGAA--QGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTL 59 ++GK ALV G + +G A A L GA+VAL + E L E L Sbjct: 5 DLSGKKALVMGVTNQRSLGFAIAAKLKEAGAEVAL-SYQAERLRPEAEKLAEALGG--AL 61 Query: 60 FIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV------------NNEKNWEKTLQIN 107 + DV ++L F V + FG LD LV+ ++W L+++ Sbjct: 62 LFRADVTQDEELDALFAGVKEAFGGLDYLVHAIAFAPREAMEGRYIDTRRQDWLLALEVS 121 Query: 108 LVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 S+++ + + GG I+ ++ A V + V +K + R L Sbjct: 122 AYSLVAVARRAEPLLRE-----GGGIVTLTYYASEKVVPKYNVMAIAKAALEASVRY--L 174 Query: 168 AANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIAN 227 A L GVR+NAI G V T SI M D + + + N Sbjct: 175 AYELGPKGVRVNAISAGPVRTVAARSIPGFTKMY------DRVAQTAPLRRNITQEEVGN 228 Query: 228 GLITLIEDDA--LNGAIMKITTS 248 + L+ A + G ++ + Sbjct: 229 LGLFLLSPLASGITGEVVYVDAG 251 >3DWF-A nrPDB Length = 276 Score = 143 bits (360), Expect = 9e-35, Method: Composition-based stats. Identities = 45/195 (23%), Positives = 79/195 (40%), Gaps = 13/195 (6%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 + GK +VTGA++GIGR A L GA V + + EA + A E +I Sbjct: 9 LQGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLE-LGAASAHYIA 67 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNW--------EKTLQINLVSVISG 114 + D + + + G LD+L+ N + N + K++++N S + Sbjct: 68 GSMEDMTFAEEFVAEAGNLMGGLDMLILNHVLYNRLTFFHGEIDNVRKSMEVNFHSFVVL 127 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 + + + + G I +SS+AG + Y ASK + GF + + Sbjct: 128 SVAAMPMLMQSQ----GSIAVVSSVAGKITYPLIAPYSASKFALDGFFSTLRSEFLVNKV 183 Query: 175 GVRLNAICPGFVNTA 189 V + G ++T Sbjct: 184 NVSITLCILGLIDTE 198 >2BFA-A nrPDB Length = 288 Score = 143 bits (360), Expect = 1e-34, Method: Composition-based stats. Identities = 59/286 (20%), Positives = 104/286 (36%), Gaps = 55/286 (19%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVA 66 VALVTGAA+ +GR+ AE L +G V L A +A P + +Q D++ Sbjct: 8 VALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLS 67 Query: 67 DQQQ-----------------LRDTFRKVVDHFGRLDILVNNAGVN-------NEKN--- 99 + + H+GR D+LVNNA N+++ Sbjct: 68 NVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHE 127 Query: 100 ----WEKTLQINLVSVISGTYLGLDYMSKQNG-----------GEGGIIINMSSLAGLMP 144 + ++ + + ++ K G IINM P Sbjct: 128 PCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQP 187 Query: 145 VAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYI 204 + +Y +K + G TRSAAL L +R+N + PG + +++ + Sbjct: 188 LLGYTIYTMAKGALEGLTRSAAL--ELAPLQIRVNGVGPGL--SVLVDDMP-------PA 236 Query: 205 EYKDHIKDMIKYYGILDPPLIANGLITLIEDDA--LNGAIMKITTS 248 ++ H + Y +++ +I L A + G +K+ Sbjct: 237 VWEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGG 282 >1A27-A nrPDB Length = 289 Score = 142 bits (359), Expect = 1e-34, Method: Composition-based stats. Identities = 66/255 (25%), Positives = 103/255 (40%), Gaps = 30/255 (11%) Query: 7 VALVTGAAQGIGRAFAEALLLKG---AKVALVDWNLE-AGVQCKAALDEQFEPQKTLFIQ 62 V L+TG + GIG A L KV +L+ G +AA P +Q Sbjct: 4 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 63 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISG 114 DV D + + +V + GR+D+LV NAG+ E L +N+V + Sbjct: 64 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 121 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 L M ++ G ++ S+ GLM + VYCASK + G S LA L+ Sbjct: 122 LQAFLPDMKRRGSGR---VLVTGSVGGLMGLPFNDVYCASKFALEGLCES--LAVLLLPF 176 Query: 175 GVRLNAICPGFVNTAILESIEKEEN----------MGQYIEYKDHIKDMIKYYGILDPPL 224 GV L+ I G V+TA +E + ++ +Y H K + + +P Sbjct: 177 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFR-EAAQNPEE 235 Query: 225 IANGLITLIEDDALN 239 +A +T + Sbjct: 236 VAEVFLTALRAPKPT 250 >6CGE-A nrPDB Length = 328 Score = 141 bits (357), Expect = 2e-34, Method: Composition-based stats. Identities = 66/255 (25%), Positives = 103/255 (40%), Gaps = 30/255 (11%) Query: 7 VALVTGAAQGIGRAFAEALLLKG---AKVALVDWNLE-AGVQCKAALDEQFEPQKTLFIQ 62 V L+TG + GIG A L KV +L+ G +AA P +Q Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISG 114 DV D + + +V + GR+D+LV NAG+ E L +N+V + Sbjct: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 Query: 115 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 174 L M ++ G ++ S+ GLM + VYCASK + G S LA L+ Sbjct: 123 LQAFLPDMKRRGSGR---VLVTGSVGGLMGLPFNDVYCASKFALEGLCES--LAVLLLPF 177 Query: 175 GVRLNAICPGFVNTAILESIEKEEN----------MGQYIEYKDHIKDMIKYYGILDPPL 224 GV L+ I G V+TA +E + ++ +Y H K + + +P Sbjct: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFR-EAAQNPEE 236 Query: 225 IANGLITLIEDDALN 239 +A +T + Sbjct: 237 VAEVFLTALRAPKPT 251 >3U4C-A nrPDB Length = 281 Score = 141 bits (357), Expect = 2e-34, Method: Composition-based stats. Identities = 51/264 (19%), Positives = 104/264 (39%), Gaps = 24/264 (9%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 H++ + A V GA+QGIG+A A L + + + NL+ K + + + + Sbjct: 20 HMSKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVL 79 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWE--------KTLQINLVSVIS 113 D++DQ F+K+ GRLD+L+NN ++ T V+ I Sbjct: 80 AGDMSDQHTRAGIFQKIESQCGRLDVLINNIPGGAPDTFDNCNIEDMTATFTQKTVAYID 139 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCAS--KHGIVGFTRSAALAANL 171 M + G IIN+ + L ++ S ++ +++ ++ L Sbjct: 140 AIKRASSLMKQNEFGR---IINI--VGNLWKEPGANMFTNSMMNAALINASKN--ISIQL 192 Query: 172 MNSGVRLNAICPGFVNTA----ILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIAN 227 + +N + PGF+ T +E++ K+ ++ + + ++ I I + A Sbjct: 193 APHNITVNCLNPGFIATDRYHQFVENVMKKNSISKQ-KAEEQIASGIPMKRVGSAEETAA 251 Query: 228 GLITLIEDDA--LNGAIMKITTSK 249 L ++A + G + Sbjct: 252 LAAFLASEEASYITGQQISADGGS 275 >1MG5-A nrPDB Length = 255 Score = 141 bits (355), Expect = 3e-34, Method: Composition-based stats. Identities = 58/252 (23%), Positives = 103/252 (40%), Gaps = 15/252 (5%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTL 59 + K + GIG ++ LL + K + ++D A L Sbjct: 2 FTLTNKNVIFVAGLGGIGLDTSKELLKRDLKNLVILDRIE--NPAAIAELKAINPKVTVT 59 Query: 60 FIQCDVADQ-QQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLG 118 F DV + + + +D+L+N AG+ ++ E+T+ +N +++ T Sbjct: 60 FYPYDVTVPIAETTKLLKTIFAQLKTVDVLINGAGILDDHQIERTIAVNYTGLVNTTTAI 119 Query: 119 LDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN-SGVR 177 LD+ K+ GG GGII N+ S+ G + Q PVY +K +V FT S A L +GV Sbjct: 120 LDFWDKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAK---LAPITGVT 176 Query: 178 LNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDA 237 + PG T ++ +++ + + + + + A + IE + Sbjct: 177 AYTVNPGITRTTLVH------KFNSWLDVEPQVAEKLLAHPTQPSLACAENFVKAIELNQ 230 Query: 238 LNGAIMKITTSK 249 NGAI K+ Sbjct: 231 -NGAIWKLDLGT 241 >3E9N-A nrPDB Length = 245 Score = 137 bits (345), Expect = 6e-33, Method: Composition-based stats. Identities = 54/247 (21%), Positives = 93/247 (37%), Gaps = 35/247 (14%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M + K+A+VTGA G+G + L V + N E L E + Sbjct: 1 MSLKKKIAVVTGATGGMGIEIVKDLSRD-HIVYALGRNPEH-------LAALAEIEGVEP 52 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--------KNWEKTLQINLVSVI 112 I+ D+ + K+ + +D LV+ A V + W L +N++ Sbjct: 53 IESDIVKEVLEEGGVDKL-KNLDHVDTLVHAAAVARDTTIEAGSVAEWHAHLDLNVIVPA 111 Query: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 172 + L + G +I ++S AG P +Y ASKH + G A Sbjct: 112 ELSRQLLPALRAA----SGCVIYINSGAGNGPHPGNTIYAASKHALRGLA--DAFRKEEA 165 Query: 173 NSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITL 232 N+G+R++ + PG NT +L+ + + E ++P IAN + + Sbjct: 166 NNGIRVSTVSPGPTNTPMLQGLMDSQGTNFRPEI------------YIEPKEIANAIRFV 213 Query: 233 IEDDALN 239 I+ Sbjct: 214 IDAGETT 220 >2HRB-A nrPDB Length = 274 Score = 136 bits (344), Expect = 8e-33, Method: Composition-based stats. Identities = 58/237 (24%), Positives = 83/237 (35%), Gaps = 59/237 (24%) Query: 6 KVALVTGAAQGIGRAFAEALLLK-GAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64 +VALVTGA +GIG A A L + V L ++ G L Q E F Q D Sbjct: 3 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQL--QAEGLSPRFHQLD 60 Query: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKN--------WEKTLQINLVSVISGTY 116 + D Q +R + +G L++LVNNA V + + E TL+ N + + Sbjct: 61 IDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCN 120 Query: 117 LGLDYMSKQNGGEGGIIINMSSLAGLMPVAQ----------------------------- 147 L M G ++N+SSL L Sbjct: 121 ELLPIMKPH-----GRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVED 175 Query: 148 ------------QPVYCASKHGIVGFTRSAALAANLMNS--GVRLNAICPGFVNTAI 190 Y SK G+ +R A + + +NA CPG V T + Sbjct: 176 TKNEVHEREGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDM 232 >3KZV-A nrPDB Length = 254 Score = 133 bits (336), Expect = 5e-32, Method: Composition-based stats. Identities = 59/252 (23%), Positives = 102/252 (40%), Gaps = 24/252 (9%) Query: 5 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64 GKV LVTG ++GIG++ + L + + + L E++ + ++ D Sbjct: 2 GKVILVTGVSRGIGKSIVDVLFSLDKDTVV--YGVARSEAPLKKLKEKY-GDRFFYVVGD 58 Query: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKN---------WEKTLQINLVSVISGT 115 + + L+ V G++D LV NAGV W+K IN S++S Sbjct: 59 ITEDSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNEIDVNAWKKLYDINFFSIVSLV 118 Query: 116 YLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSG 175 + L + K N G ++ +SS A M + Y +SK + F + LA Sbjct: 119 GIALPELKKTN----GNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMT--LANE--ERQ 170 Query: 176 VRLNAICPGFVNTAILESIEKEENMGQY-IEYKDHIKDMIKYYGILDPPLIANGLITLI- 233 V+ A+ PG V+T + +I + E + + + +LD + A L Sbjct: 171 VKAIAVAPGIVDTDMQVNIRENVGPSSMSAEQLKMFRGLKENNQLLDSSVPATVYAKLAL 230 Query: 234 --EDDALNGAIM 243 D +NG + Sbjct: 231 HGIPDGVNGQYL 242 >5KOI-A nrPDB Length = 293 Score = 133 bits (336), Expect = 6e-32, Method: Composition-based stats. Identities = 53/263 (20%), Positives = 93/263 (35%), Gaps = 33/263 (12%) Query: 3 VNGKVALVTGAA--QGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + GK L+ G A + A+ L +GA++A G + K ++ Sbjct: 26 MQGKRGLIMGVANNHSLAWGIAKQLAAQGAELAFTYQGDALGKRVKPLAEQV---GSDFV 82 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAG-------------VNNEKNWEKTLQIN 107 + CDV D + F ++ +G LD LV+ G V +N+ +T+ I+ Sbjct: 83 LPCDVEDIATVDAVFEEIEKKWGGLDFLVHAIGFSDKTELKGRYADVTTRENFSRTMVIS 142 Query: 108 LVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 S M +GG I+ ++ + V +K + R L Sbjct: 143 AYSFTEVAQRAEKLMK-----DGGSILTLTYGGSTRTIPNYNVMGVAKAALEAMVRY--L 195 Query: 168 AANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIAN 227 AA+ G+R+NAI G V T I + Y + +D + Sbjct: 196 AADYGPQGIRVNAISAGPVRTLAGAGIGDARAIFSY------QRRNSPLRRTVDIDDVGK 249 Query: 228 GLITLIED--DALNGAIMKITTS 248 + L+ D + G I + + Sbjct: 250 SAVYLLSDLSSGVTGEIHFVDSG 272 >1N5D-A nrPDB Length = 288 Score = 131 bits (330), Expect = 3e-31, Method: Composition-based stats. Identities = 57/237 (24%), Positives = 86/237 (36%), Gaps = 59/237 (24%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGA-KVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64 +VALVTGA +GIG A L + A V L ++ G L Q E F Q D Sbjct: 5 RVALVTGANKGIGFAIVRDLCRQFAGDVVLTARDVARGQAAVKQL--QAEGLSPRFHQLD 62 Query: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNW--------EKTLQINLVSVISGTY 116 + D Q +R + +G LD+LVNNA + + + E T++ N + + Sbjct: 63 IIDLQSIRALCDFLRKEYGGLDVLVNNAAIAFQLDNPTPFHIQAELTMKTNFMGTRNVCT 122 Query: 117 LGLDYMSKQNGGEGGIIINMSSLAGLMPV------------------------------- 145 L + Q G ++N+SS G+ + Sbjct: 123 ELLPLIKPQ-----GRVVNVSSTEGVRALNECSPELQQKFKSETITEEELVGLMNKFVED 177 Query: 146 ----------AQQPVYCASKHGIVGFTRSAA--LAANLMNSGVRLNAICPGFVNTAI 190 Y +K G+ +R A L + LNA CPG+V T + Sbjct: 178 TKNGVHRKEGWSDSTYGVTKIGVSVLSRIYARKLREQRAGDKILLNACCPGWVRTDM 234 >3OIG-A nrPDB Length = 266 Score = 130 bits (327), Expect = 6e-31, Method: Composition-based stats. Identities = 47/269 (17%), Positives = 95/269 (35%), Gaps = 32/269 (11%) Query: 1 MHVNGKVALVTGAA--QGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKT 58 + G+ +V G A + I A +L GA++ E + L + + Sbjct: 3 FSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAG-ERLEKSVHELAGTLDRNDS 61 Query: 59 LFIQCDVADQQQLRDTFRKVVDHFGRLDILVNN-AGVNNEKNWEKTLQINLVSVIS---- 113 + + CDV + ++ F + + G + + + A N E+ + L N + Sbjct: 62 IILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNI 121 Query: 114 -------GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAA 166 M++ GG I+ ++ L G + + V +K + + Sbjct: 122 SSYSLTAVVKAARPMMTE-----GGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKY-- 174 Query: 167 LAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIA 226 LAA+L +R+N+I G + T + I ++ + IE + P + Sbjct: 175 LAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEER------APLRRTTTPEEVG 228 Query: 227 NGLITLIED--DALNGAIMKITTSKGIHF 253 + L D + G + + G H Sbjct: 229 DTAAFLFSDMSRGITGENLHVD--SGFHI 255 >4NR0-A nrPDB Length = 273 Score = 130 bits (326), Expect = 8e-31, Method: Composition-based stats. Identities = 58/263 (22%), Positives = 95/263 (36%), Gaps = 30/263 (11%) Query: 3 VNGKVALVTGAAQ--GIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + GK AL+ G A I A A+ +GA++A N + + + L Sbjct: 4 LTGKRALIVGVASKLSIASGIAAAMHREGAELAFTYQN-DKLRGRVEEFASGWGSRPELC 62 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAG-------------VNNEKNWEKTLQIN 107 CDVAD Q+ F + H+ LDI+V++ G V + + I+ Sbjct: 63 FPCDVADDSQIEAVFAALGKHWDGLDIIVHSVGFAPGDQLDGDFTAVTTREGFRIAHDIS 122 Query: 108 LVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 S I+ G + M G G ++ +S L + V +K + R L Sbjct: 123 AYSFIALAKAGREMMK----GRNGSLLTLSYLGAERTMPNYNVMGMAKASLEAGVRY--L 176 Query: 168 AANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIAN 227 A +L G R+NA+ G + T I+ M E + + N Sbjct: 177 AGSLGAEGTRVNAVSAGPIRTLAASGIKSFRKMLAANE------RQTPLRRNVTIEEVGN 230 Query: 228 GLITLIEDDA--LNGAIMKITTS 248 L D A ++G I+ + Sbjct: 231 AGAFLCSDLASGISGEILYVDGG 253 >4DRY-A nrPDB Length = 281 Score = 129 bits (324), Expect = 2e-30, Method: Composition-based stats. Identities = 49/180 (27%), Positives = 66/180 (36%), Gaps = 13/180 (7%) Query: 21 FAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVVD 80 A+AL +G V + + + + CDV D Q+ F V Sbjct: 49 IAQALSAEGYSVVITGRRPDVLDAAAGEIG-GRTGNIVRAVVCDVGDPDQVAALFAAVRA 107 Query: 81 HFGRLDILVNNAGVN---------NEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGG 131 F RLD+LVNNAG N + W + NL T M Q GG Sbjct: 108 EFARLDLLVNNAGSNVPPVPLEEVTFEQWNGIVAANLTGAFLCTQHAFRMMKAQTP-RGG 166 Query: 132 IIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAIL 191 IIN S++ P Y A+KH I G T+S AL + + I G T + Sbjct: 167 RIINNGSISAQTPRPNSAPYTATKHAITGLTKSTALDGRM--HDIACGQIDIGNAATDMT 224 >3BHI-A nrPDB Length = 276 Score = 127 bits (319), Expect = 6e-30, Method: Composition-based stats. Identities = 55/236 (23%), Positives = 80/236 (33%), Gaps = 59/236 (25%) Query: 7 VALVTGAAQGIGRAFAEALLLK-GAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 VALVTG +GIG A L V L ++ G L Q E F Q D+ Sbjct: 6 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQL--QAEGLSPRFHQLDI 63 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISGTYL 117 D Q +R + +G LD+LVNNAG+ E T++ N Sbjct: 64 DDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCTE 123 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQ------------------------------ 147 L + Q G ++N+SS+ + + Sbjct: 124 LLPLIKPQ-----GRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDT 178 Query: 148 -----------QPVYCASKHGIVGFTRSAALAANLMNSG--VRLNAICPGFVNTAI 190 Y +K G+ +R A + G + LNA CPG+V T + Sbjct: 179 KKGVHQKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDM 234 >5TF4-A nrPDB Length = 274 Score = 125 bits (314), Expect = 2e-29, Method: Composition-based stats. Identities = 53/262 (20%), Positives = 101/262 (38%), Gaps = 32/262 (12%) Query: 3 VNGKVALVTGAA--QGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + GK L+ G A + I A+ GA++A EA + L E+ + + Sbjct: 10 LYGKRGLILGLANNRSIAWGIAKTASSAGAELAFTYQG-EAMKKRVEPLAEEVKG--FVC 66 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN------------NEKNWEKTLQINL 108 CDV+D + F + +G+LD LV+ G + +E N+ T+ I++ Sbjct: 67 GHCDVSDSASIDAVFNTIEKKWGKLDFLVHAIGFSDKEELSGRYVDISESNFMMTMNISV 126 Query: 109 VSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALA 168 S+ + T M +GG I+ ++ V V +K + + LA Sbjct: 127 YSLTALTKRAEKLM-----SDGGSILTLTYYGAEKVVPNYNVMGVAKAALEASVKY--LA 179 Query: 169 ANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANG 228 +L +R+NAI G + T I + ++ EY + + + Sbjct: 180 VDLGPKHIRVNAISAGPIKTLAASGIGDFRYILKWNEYN------APLRRTVTIEEVGDS 233 Query: 229 LITLIED--DALNGAIMKITTS 248 + L+ D ++ G + + + Sbjct: 234 ALYLLSDLSRSVTGEVHHVDSG 255 >5YCX-A nrPDB Length = 266 Score = 124 bits (312), Expect = 3e-29, Method: Composition-based stats. Identities = 56/265 (21%), Positives = 101/265 (38%), Gaps = 28/265 (10%) Query: 3 VNGKVALVTGAA--QGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + GK +V G A + I A +L GAK+ E + L + E Q++L Sbjct: 6 LQGKTFVVMGVANQRSIAWGIARSLHNAGAKLIFTYAG-ERLERNVRELADTLEGQESLV 64 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWE----------KTLQINLVS 110 + CDV + ++L F + G + + + N + + L N+ S Sbjct: 65 LPCDVTNDEELTACFETIKQEVGTIHGVAHCIAFANRDDLKGEFVDTSRDGFLLAQNI-S 123 Query: 111 VISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAAN 170 S T + + K+ EGG I+ ++ L G V V +K + + LA + Sbjct: 124 AFSLTAVAREA--KKVMTEGGNILTLTYLGGERVVKNYNVMGVAKASLEASVKY--LAND 179 Query: 171 LMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLI 230 L G+R+NAI G + T + + ++ + IE + + + + Sbjct: 180 LGQHGIRVNAISAGPIRTLSAKGVGDFNSILREIEER------APLRRTTTQEEVGDTAV 233 Query: 231 TLIEDDA--LNGAIMKITTSKGIHF 253 L D A + G + + G H Sbjct: 234 FLFSDLARGVTGENIHVD--SGYHI 256 >3GRK-A nrPDB Length = 293 Score = 122 bits (307), Expect = 1e-28, Method: Composition-based stats. Identities = 51/267 (19%), Positives = 98/267 (36%), Gaps = 34/267 (12%) Query: 3 VNGKVALVTGAA--QGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + GK L+ G A + I A+A GA++A + + +E + Sbjct: 29 LQGKRGLILGVANNRSIAWGIAKAAREAGAELAFTYQGDALKKRVEPLAEELGA---FVA 85 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV------------NNEKNWEKTLQINL 108 CDVAD + F + +G+LD LV+ G +E N+ T+ I++ Sbjct: 86 GHCDVADAASIDAVFETLEKKWGKLDFLVHAIGFSDKDELTGRYIDTSEANFTNTMLISV 145 Query: 109 VSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALA 168 S+ + + M+ +GG I+ ++ + V +K + + LA Sbjct: 146 YSLTAVSRRAEKLMA-----DGGSILTLTYYGAEKVMPNYNVMGVAKAALEASVKY--LA 198 Query: 169 ANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANG 228 +L +R+NAI G + T I + ++ EY + + + Sbjct: 199 VDLGPQNIRVNAISAGPIKTLAASGIGDFRYILKWNEYN------APLRRTVTIDEVGDV 252 Query: 229 LITLIED--DALNGAIMKITTSKGIHF 253 + + D ++ G + G H Sbjct: 253 GLYFLSDLSRSVTGEVHHAD--SGYHV 277 >4M89-A nrPDB Length = 261 Score = 122 bits (307), Expect = 2e-28, Method: Composition-based stats. Identities = 50/267 (18%), Positives = 92/267 (34%), Gaps = 32/267 (11%) Query: 3 VNGKVALVTG--AAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + GK L+TG + + I A+A +GA++A + + + E L Sbjct: 4 LQGKKILITGMISERSIAYGIAKACREQGAELAFTYVVDKLEERVRKMAAEL---DSELV 60 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN-------------NEKNWEKTLQIN 107 +CDVA ++ F + H+ LD LV++ G + + + +I+ Sbjct: 61 FRCDVASDDEINQVFADLGKHWDGLDGLVHSIGFAPKEALSGDFLDSISREAFNTAHEIS 120 Query: 108 LVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 S+ + M G I+ +S L + + V +K + R A Sbjct: 121 AYSLPALAKAARPMMR----GRNSAIVALSYLGAVRAIPNYNVMGMAKASLEAGIRFTAA 176 Query: 168 AANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIAN 227 L G+R N I G + T I + + H+ + + N Sbjct: 177 C--LGKEGIRCNGISAGPIKTLAASGIAD------FGKLLGHVAAHNPLRRNVTIEEVGN 228 Query: 228 GLITLIED--DALNGAIMKITTSKGIH 252 L+ D + G I + I+ Sbjct: 229 TAAFLLSDLSSGITGEITYVDGGYSIN 255 >4ZJU-A nrPDB Length = 275 Score = 120 bits (301), Expect = 8e-28, Method: Composition-based stats. Identities = 48/263 (18%), Positives = 97/263 (36%), Gaps = 32/263 (12%) Query: 3 VNGKVALVTGAAQ--GIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + GK L+ G A I A+AL +GA++A N + + ++ L Sbjct: 14 LAGKRFLIAGVASKLSIAYGIAQALHREGAELAFTYPNEKLKKRVDEFAEQF---GSKLV 70 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAG-------------VNNEKNWEKTLQIN 107 CDVA ++ + F ++ H+ +D +V++ G V + ++ I+ Sbjct: 71 FPCDVAVDAEIDNAFAELAKHWDGVDGVVHSIGFAPAHTLDGDFTDVTDRDGFKIAHDIS 130 Query: 108 LVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 S ++ + + G ++ ++ + V +K + R L Sbjct: 131 AYSFVAMARAAKPLLQARQ----GCLLTLTYQGSERVMPNYNVMGMAKASLEAGVRY--L 184 Query: 168 AANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIAN 227 A++L G+R+NAI G + T I+ M D + + + + N Sbjct: 185 ASSLGVDGIRVNAISAGPIRTLAASGIKSFRKM------LDANEKVAPLKRNVTIEEVGN 238 Query: 228 GLITLIEDDA--LNGAIMKITTS 248 + L A + G I+ + Sbjct: 239 AALFLCSPWASGITGEILYVDAG 261 >5L51-A nrPDB Length = 324 Score = 119 bits (299), Expect = 1e-27, Method: Composition-based stats. Identities = 51/275 (18%), Positives = 87/275 (31%), Gaps = 95/275 (34%) Query: 4 NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI-- 61 + A+VTGA +GIG + L KG V L + + G++ + L ++ + ++ Sbjct: 14 TKRYAVVTGANKGIGFEICKQLASKGITVILASRDEKRGIEARERLIKELGSEFGDYVVS 73 Query: 62 -QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN------------------------- 95 Q DVAD + + FG LDILVNNAG+N Sbjct: 74 QQLDVADPASVAALVDFIKTKFGSLDILVNNAGLNGTYMEGDASVLNDYVEAEFKTFQSG 133 Query: 96 -----------------NEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSS 138 ++ ++ ++ N T + + + + I+N+SS Sbjct: 134 AAKTEPYHPKATGRLVETVEHAKECIETNYYGSKRVTEALIPLLQQSDSPR---IVNVSS 190 Query: 139 LAGLMPV-------------------------------------------AQQPVYCASK 155 + Y SK Sbjct: 191 TLSSLVFQTNEWAKGVFSSEEGLTEEKLEEVLAEFLKDFIDGKQQEKQWPPHFSAYKVSK 250 Query: 156 HGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAI 190 + +TR A R+NA+CPG+ T + Sbjct: 251 AALNAYTRIIAKKY----PSFRINAVCPGYTKTDL 281 >5I9N-A nrPDB Length = 276 Score = 118 bits (297), Expect = 2e-27, Method: Composition-based stats. Identities = 53/263 (20%), Positives = 94/263 (35%), Gaps = 33/263 (12%) Query: 3 VNGKVALVTG--AAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 ++GK L+TG + + I A+A +GA++A + E L Sbjct: 4 LDGKRILLTGLLSNRSIAYGIAKACKREGAELAFTYVGDRFKDRITEFAAEFGSE---LV 60 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN-------------NEKNWEKTLQIN 107 CDVAD Q+ F + H+ LD LV++ G +N+ I+ Sbjct: 61 FPCDVADDAQIDALFASLKTHWDSLDGLVHSIGFAPREAIAGDFLDGLTRENFRIAHDIS 120 Query: 108 LVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 S + L +S ++ +S L + +K + R L Sbjct: 121 AYSFPALAKAALPMLSDD-----ASLLTLSYLGAERAIPNYNTMGLAKAALEASVRY--L 173 Query: 168 AANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIAN 227 A +L GVR+NAI G + T I+ + + D ++ + + N Sbjct: 174 AVSLGAKGVRVNAISAGPIKTLAASGIK------SFGKILDFVESNSPLKRNVTIEQVGN 227 Query: 228 GLITLIEDDA--LNGAIMKITTS 248 L+ D A + +M + + Sbjct: 228 AGAFLLSDLASGVTAEVMHVDSG 250 >1W73-A nrPDB Length = 302 Score = 118 bits (295), Expect = 3e-27, Method: Composition-based stats. Identities = 55/257 (21%), Positives = 98/257 (38%), Gaps = 20/257 (7%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 GKVA +TG G+G+ L GA+ + ++ + Q K I Sbjct: 23 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQT-GNKVHAI 81 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVIS 113 QCDV D +++T +++ G +I++NNA N + W+ I L Sbjct: 82 QCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAF 141 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 T + K +G ++++++ ++K G+ ++S LAA Sbjct: 142 VTLEIGKQLIKAQ--KGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKS--LAAEWGK 197 Query: 174 SGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLI 233 G+R N I PG + T + ++ + I + +AN L Sbjct: 198 YGMRFNVIQPGPIKTK-----GAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLC 252 Query: 234 EDDA--LNGAIMKITTS 248 D A +NGA++K Sbjct: 253 SDYASWINGAVIKFDGG 269 >5CFZ-A nrPDB Length = 305 Score = 118 bits (295), Expect = 4e-27, Method: Composition-based stats. Identities = 48/263 (18%), Positives = 96/263 (36%), Gaps = 33/263 (12%) Query: 3 VNGKVALVTGAAQ--GIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 ++GK LVTG A I A+A+ +GA++A N + + + + + Sbjct: 47 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQL---GSDIV 103 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN-------------NEKNWEKTLQIN 107 +QCDVA+ + F ++ + + D V++ G + ++ I+ Sbjct: 104 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 163 Query: 108 LVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 S ++ + G ++ +S L + V +K + R A Sbjct: 164 SYSFVAMAKACRSML-----NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMAN 218 Query: 168 AANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIAN 227 A + GVR+NAI G + T I+ M H + + + + N Sbjct: 219 A--MGPEGVRVNAISAGPIRTLAASGIKDFRKM------LAHCEAVTPIRRTVTIEDVGN 270 Query: 228 GLITLIEDDA--LNGAIMKITTS 248 L D + ++G ++ + Sbjct: 271 SAAFLCSDLSAGISGEVVHVDGG 293 >4JQC-A nrPDB Length = 282 Score = 116 bits (292), Expect = 8e-27, Method: Composition-based stats. Identities = 48/263 (18%), Positives = 96/263 (36%), Gaps = 33/263 (12%) Query: 3 VNGKVALVTGAAQ--GIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 ++GK LVTG A I A+A+ +GA++A N + + + + + Sbjct: 24 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQL---GSDIV 80 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN-------------NEKNWEKTLQIN 107 +QCDVA+ + F ++ + + D V++ G + ++ I+ Sbjct: 81 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 140 Query: 108 LVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 S ++ + G ++ +S L + V +K + R A Sbjct: 141 SYSFVAMAKACRSML-----NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMAN 195 Query: 168 AANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIAN 227 A + GVR+NAI G + T I+ M H + + + + N Sbjct: 196 A--MGPEGVRVNAISAGPIRTLAASGIKDFRKM------LAHCEAVTPIRRTVTIEDVGN 247 Query: 228 GLITLIEDDA--LNGAIMKITTS 248 L D + ++G ++ + Sbjct: 248 SAAFLCSDLSAGISGEVVHVDGG 270 >3K2E-A nrPDB Length = 296 Score = 116 bits (290), Expect = 1e-26, Method: Composition-based stats. Identities = 53/268 (19%), Positives = 100/268 (37%), Gaps = 36/268 (13%) Query: 1 MHVNGKVALVTGAA--QGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKT 58 M + GK ++ G A + + A+A+ +GA+VAL + E + L E + Sbjct: 26 MLMEGKKGVIIGVANDKSLAWGIAKAVCAQGAEVALTYLS-ETFKKRVDPLAESLGVK-- 82 Query: 59 LFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV------------NNEKNWEKTLQI 106 L + CDV+D + + + F+ + + +G LD +V+ + N+ ++ I Sbjct: 83 LTVPCDVSDAESVDNMFKVLAEEWGSLDFVVHAVAFSDKNELKGRYVDTSLGNFLTSMHI 142 Query: 107 NLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAA 166 + S M+ GG I+ +S V V K + + Sbjct: 143 SCYSFTYIASKAEPLMT-----NGGSILTLSYYGAEKVVPHYNVMGVCKAALEASVKY-- 195 Query: 167 LAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIA 226 LA +L +R+NAI G V T I + + +Y ++ + Sbjct: 196 LAVDLGKQQIRVNAISAGPVRTLASSGISDFHYILTWNKYNSPLRRNTTL------DDVG 249 Query: 227 NGLITLIEDDALNGAIMKITTSKGIHFQ 254 + L+ D + TT + +H Sbjct: 250 GAALYLLSDLG------RGTTGETVHVD 271 >4J3F-A nrPDB Length = 280 Score = 113 bits (284), Expect = 7e-26, Method: Composition-based stats. Identities = 47/263 (17%), Positives = 92/263 (34%), Gaps = 33/263 (12%) Query: 3 VNGKVALVTG--AAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + GK L+TG + + I A+A+ +GA++A G E Sbjct: 24 LAGKKILITGLLSNKSIAYGIAKAMHREGAELAFTYV----GQFKDRVEKLCAEFNPAAV 79 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN-------------NEKNWEKTLQIN 107 + CDV Q+++D F ++ + LD +V++ + + I+ Sbjct: 80 LPCDVISDQEIKDLFVELGKVWDGLDAIVHSIAFAPRDQLEGNFIDCVTREGFSIAHDIS 139 Query: 108 LVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 S + G M ++ ++ + + +K + R AL Sbjct: 140 AYSFAALAKEGRSMMK----NRNASMVALTYIGAEKAMPSYNTMGVAKASLEATVRYTAL 195 Query: 168 AANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIAN 227 A L G+++NA+ G + T I + M Y +K + D + N Sbjct: 196 A--LGEDGIKVNAVSAGPIKTLAASGISNFKKMLDYNAMVSPLKKNV------DIMEVGN 247 Query: 228 GLITLIEDDA--LNGAIMKITTS 248 + L D A + G ++ + Sbjct: 248 TVAFLCSDMATGITGEVVHVDAG 270 >4NK4-A nrPDB Length = 301 Score = 113 bits (284), Expect = 7e-26, Method: Composition-based stats. Identities = 48/262 (18%), Positives = 90/262 (34%), Gaps = 32/262 (12%) Query: 3 VNGKVALVTGAA--QGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + GK L+ G A I A+ L GA++A G + K Sbjct: 39 LKGKRGLIMGVANDHSIAWGIAKVLHSAGAQLAFSYQGESIGKRLKPL---ALTVDSDFM 95 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV------------NNEKNWEKTLQINL 108 I C+V D + F ++ + + LD +V++ + N+ +T+ ++ Sbjct: 96 IPCNVEDPSSMDLLFERIKERWETLDFVVHSIAFSDKNELRGPYYNTSRDNFIQTMLVSC 155 Query: 109 VSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALA 168 S M GG +I ++ + V +K + T+ LA Sbjct: 156 FSFTEIVRRAAQLMP-----HGGAMITLTYGGSMRVVPNYNAMAPAKSALESSTKY--LA 208 Query: 169 ANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANG 228 + +R+NAI G V T SI ++ + + +K + I N Sbjct: 209 CDYGGMNIRINAISAGPVRTLAGASISNGRDIAAWSKENSPLKRTVSL------EDIGNS 262 Query: 229 LITLIE--DDALNGAIMKITTS 248 + L+ + + G I + Sbjct: 263 ALYLLSYLSNGVTGEIHYVDCG 284 >3O26-A nrPDB Length = 311 Score = 113 bits (282), Expect = 1e-25, Method: Composition-based stats. Identities = 58/305 (19%), Positives = 92/305 (30%), Gaps = 92/305 (30%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 + A+VTG +GIG + L G V L ++ G + L + +F Q DV Sbjct: 13 RCAVVTGGNKGIGFEICKQLSSNGIMVVLTCRDVTKGHEAVEKLKNS-NHENVVFHQLDV 71 Query: 66 ADQ-QQLRDTFRKVVDHFGRLDILVNNAGVN----NEKNWEKTLQ--------------- 105 D + + HFG+LDILVNNAGV + ++ + Sbjct: 72 TDPIATMSSLADFIKTHFGKLDILVNNAGVAGFSVDADRFKAMISDIGEDSEELVKIYEK 131 Query: 106 -------------------INLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLM--- 143 IN V S T + + + + I+N+SS G + Sbjct: 132 PEAQELMSETYELAEECLKINYNGVKSVTEVLIPLL---QLSDSPRIVNVSSSTGSLKYV 188 Query: 144 ---------------------------------------PVAQQ-PVYCASKHGIVGFTR 163 Y SK + +TR Sbjct: 189 SNETALEILGDGDALTEERIDMVVNMLLKDFKENLIETNGWPSFGAAYTTSKACLNAYTR 248 Query: 164 SAALAANLMNSGVRLNAICPGFVNTAILESIEK--EENMGQYIEYKDHIKDMIKYYGILD 221 LA + +N +CPG V T + I E +++ D D Sbjct: 249 --VLANKIPKFQ--VNCVCPGLVKTEMNYGIGNYTAEEGAEHVVRIALFPDDGPSGFFYD 304 Query: 222 PPLIA 226 ++ Sbjct: 305 CSELS 309 >4ALL-A nrPDB Length = 277 Score = 112 bits (281), Expect = 1e-25, Method: Composition-based stats. Identities = 45/264 (17%), Positives = 96/264 (36%), Gaps = 30/264 (11%) Query: 1 MHVNGKVALVTGAA--QGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKT 58 +++ K ++ G A + I A+ L GAK+ + + + L EQ + Sbjct: 23 LNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLL-EQLNQPEA 81 Query: 59 LFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV------------NNEKNWEKTLQI 106 Q DV +++ + F ++ G +D + ++ + + + I Sbjct: 82 HLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDI 141 Query: 107 NLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAA 166 + S+ + M + GG I+ + L G V V +K + + Sbjct: 142 SSYSLTIVAHEAKKLMPE-----GGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKY-- 194 Query: 167 LAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIA 226 LA +L +R+NAI G + T + + + + IE + +K + D + Sbjct: 195 LALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNV------DQVEVG 248 Query: 227 NGLITLIED--DALNGAIMKITTS 248 L+ D + G + + + Sbjct: 249 KTAAYLLSDLSSGVTGENIHVDSG 272 >2PD3-A nrPDB Length = 275 Score = 109 bits (273), Expect = 1e-24, Method: Composition-based stats. Identities = 45/265 (16%), Positives = 96/265 (36%), Gaps = 30/265 (11%) Query: 3 VNGKVALVTGAA--QGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + GK L+ G A + I A++ +GA +A N + + E P Sbjct: 4 LKGKKGLIVGVANNKSIAYGIAQSCFNQGATLAFTYLNESLEKRVRPIAQELNSP---YV 60 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV------------NNEKNWEKTLQINL 108 + DV+ ++ + + V G LD +V++ ++ + ++I++ Sbjct: 61 YELDVSKEEHFKSLYNSVKKDLGSLDFIVHSVAFAPKEALEGSLLETSKSAFNTAMEISV 120 Query: 109 VSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALA 168 S+I T + G ++ +S L +A V +K + R LA Sbjct: 121 YSLIELTNTLKPLL-----NNGASVLTLSYLGSTKYMAHYNVMGLAKAALESAVRY--LA 173 Query: 169 ANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANG 228 +L +R+NA+ G + T I + ++ E ++ + + + A Sbjct: 174 VDLGKHHIRVNALSAGPIRTLASSGIADFRMILKWNEINAPLRKNVSLEEVGN----AGM 229 Query: 229 LITLIEDDALNGAIMKITTSKGIHF 253 + ++G + + G H Sbjct: 230 YLLSSLSSGVSGEVHFVD--AGYHV 252 >3U9L-A nrPDB Length = 324 Score = 104 bits (260), Expect = 4e-23, Method: Composition-based stats. Identities = 48/195 (24%), Positives = 79/195 (40%), Gaps = 15/195 (7%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTL- 59 M ++ K+ L+TGA+ G GR AEAL G +V ++ F + Sbjct: 1 MVMSKKIILITGASSGFGRLTAEALAGAGHRVYASMRDIVGRNASNVEAIAGFARDNDVD 60 Query: 60 --FIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAG--------VNNEKNWEKTLQINLV 109 ++ DV Q + +++ GR+D+L++NAG + + + IN++ Sbjct: 61 LRTLELDVQSQVSVDRAIDQIIGEDGRIDVLIHNAGHMVFGPAEAFTPEQFAELYDINVL 120 Query: 110 SVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAA 169 S L +M +Q G I I+ SS AG P P + A + A Sbjct: 121 STQRVNRAALPHMRRQKHGLL-IWISSSSSAGGTPPYLAPYFAAKAAMDAIAVQY---AR 176 Query: 170 NLMNSGVRLNAICPG 184 L G+ + I PG Sbjct: 177 ELSRWGIETSIIVPG 191 >5WQO-A nrPDB Length = 234 Score = 103 bits (257), Expect = 1e-22, Method: Composition-based stats. Identities = 45/193 (23%), Positives = 81/193 (41%), Gaps = 18/193 (9%) Query: 8 ALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVAD 67 L+ GA++GIG A+A L +GA+V V + +A + ++ + D+ Sbjct: 9 VLIVGASRGIGLGLADAFLQRGAQVFAVARRPQGSPGLQALA--ERAGERLQAVTGDLNQ 66 Query: 68 QQQLRDTFRKVVDHFGRLDILVNNAGVNNEK-------NWEKTLQINLVSVISGTYLGLD 120 + + R+D L+ NAG+ + + E+T Q+ L + I+ L Sbjct: 67 HDCAERIGEMLGER--RIDRLIVNAGIYGPQQQDVAEIDAEQTAQLFLTNAIAPLRLARA 124 Query: 121 YMSKQNGGEGGIIINMSSLAGLMP---VAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177 + + GG++ MSS + A P+Y ASK + RS + + Sbjct: 125 LSGRVS--RGGVVAFMSSQMASLALGLSATMPLYGASKAALNSLVRSWEGEFEELPFSLL 182 Query: 178 LNAICPGFVNTAI 190 L + PG+V T + Sbjct: 183 L--LHPGWVRTEM 193 >5LCX-A nrPDB Length = 316 Score = 101 bits (252), Expect = 3e-22, Method: Composition-based stats. Identities = 38/133 (28%), Positives = 62/133 (46%), Gaps = 11/133 (8%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFE--PQKTLFIQC 63 + ALVTGA +GIG L KG V L N + G++ + L ++ + +F Q Sbjct: 8 RYALVTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKELNVSENRLVFHQL 67 Query: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEK------NWEKTLQINLVSVI---SG 114 DV D + + FG+LDILVNNAGV+ + + + ++ + ++ +G Sbjct: 68 DVTDLASVAAVAVFIKSKFGKLDILVNNAGVSGVEMVGDVSVFNEYIEADFKALQALEAG 127 Query: 115 TYLGLDYMSKQNG 127 + K NG Sbjct: 128 AKEEPPFKPKANG 140 Score = 36.4 bits (83), Expect = 0.014, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 19/46 (41%), Gaps = 4/46 (8%) Query: 146 AQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAIL 191 SK + +T+ AA R+NAICPG+ T I Sbjct: 235 PHFAAERVSKAALNAYTKIAAKKY----PSFRINAICPGYAKTDIT 276 >1SNY-A nrPDB Length = 267 Score = 101 bits (251), Expect = 5e-22, Method: Composition-based stats. Identities = 45/208 (21%), Positives = 73/208 (35%), Gaps = 30/208 (14%) Query: 8 ALVTGAAQGIGRAFAEALL---LKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64 L+TG +G+G +ALL + N E + + D ++ D Sbjct: 24 ILITGCNRGLGLGLVKALLNLPQPPQHLFTTCRNREQAKELE---DLAKNHSNIHILEID 80 Query: 65 VADQQQLRDTFRKV--VDHFGRLDILVNNAGVN---------NEKNWEKTLQINLVSVIS 113 + + + V L++L NNAG+ + TLQ N V I Sbjct: 81 LRNFDAYDKLVADIEGVTKDQGLNVLFNNAGIAPKSARITAVRSQELLDTLQTNTVVPIM 140 Query: 114 GTYLGLDYMSKQNGGE--------GGIIINMSSLAG-LMPV--AQQPVYCASKHGIVGFT 162 L + K IINMSS+ G + Y SK + T Sbjct: 141 LAKACLPLLKKAAKANESQPMGVGRAAIINMSSILGSIQGNTDGGMYAYRTSKSALNAAT 200 Query: 163 RSAALAANLMNSGVRLNAICPGFVNTAI 190 +S L+ +L + ++ PG+V T + Sbjct: 201 KS--LSVDLYPQRIMCVSLHPGWVKTDM 226 >2DKN-A nrPDB Length = 255 Score = 99.2 bits (246), Expect = 1e-21, Method: Composition-based stats. Identities = 54/275 (19%), Positives = 94/275 (34%), Gaps = 59/275 (21%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVA 66 V +TG+A GIG A E L G V +D I+ D++ Sbjct: 3 VIAITGSASGIGAALKELLARAGHTVIGIDRGQAD-------------------IEADLS 43 Query: 67 DQQQLRDTFRKVVDHFGR-LDILVNNAGVN-NEKNWEKTLQINLVSVISGTYLGLDYMSK 124 V+D G LD LV AGV N + +N V + + +S+ Sbjct: 44 TPGGRETAVAAVLDRCGGVLDGLVCCAGVGVTAANSGLVVAVNYFGVSALLDGLAEALSR 103 Query: 125 QNGGEGGIIINMSSLAGLMPVAQ--------------------------QPVYCASKHGI 158 G+ + + S+A P A Y SK+ + Sbjct: 104 ---GQQPAAVIVGSIAATQPGAAELPMVEAMLAGDEARAIELAEQQGQTHLAYAGSKYAV 160 Query: 159 VGFTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYG 218 R + + GVRLN + PG V T +L++ + + G+ + + Sbjct: 161 TCLARRNVV--DWAGRGVRLNVVAPGAVETPLLQASKADPRYGESTR-----RFVAPLGR 213 Query: 219 ILDPPLIANGLITLIEDDA--LNGAIMKITTSKGI 251 +P +A + L+ A ++G+++ + Sbjct: 214 GSEPREVAEAIAFLLGPQASFIHGSVLFVDGGMDA 248 >2O2S-A nrPDB Length = 315 Score = 92.7 bits (229), Expect = 2e-19, Method: Composition-based stats. Identities = 62/314 (19%), Positives = 105/314 (33%), Gaps = 54/314 (17%) Query: 1 MHVNGKVALVTGA--AQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKT 58 + + G+ A V G + G G A A+ L GA+VAL W G+ K+ + + + Sbjct: 5 IDLRGQTAFVAGVADSHGYGWAIAKHLASAGARVALGTWPPVLGLFQKSLQSGRLDEDRK 64 Query: 59 LF----------------------IQCDVADQQ--------QLRDTFRKVVDHFGRLDIL 88 L + D+ D + +++ KV G +DIL Sbjct: 65 LPDGSLIEFAGVYPLDAAFDKPEDVPQDIKDNKRYAGVDGYTIKEVAVKVKQDLGNIDIL 124 Query: 89 VNNAG----------VNNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSS 138 V++ + K + + S +S M EGG + +S Sbjct: 125 VHSLANGPEVTKPLLETSRKGYLAASSNSAYSFVSLLQHFGPIM-----NEGGSAVTLSY 179 Query: 139 LAGLMPVAQQ-PVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKE 197 LA V ++K + TR+ A A GVR+NAI G + + +I K Sbjct: 180 LAAERVVPGYGGGMSSAKAALESDTRTLAWEAG-QKYGVRVNAISAGPLKSRAASAIGKS 238 Query: 198 ENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIED--DALNGAIMKITTS---KGIH 252 D+ + L + + L+ A++G + + G Sbjct: 239 GEKSFIDYAIDYSYNNAPLRRDLHSDDVGGAALFLLSPLARAVSGVTLYVDNGLHAMGQA 298 Query: 253 FQDYDTTPFQAKTQ 266 P Q TQ Sbjct: 299 VDSRSMPPLQRATQ 312 >3UCF-A nrPDB Length = 223 Score = 89.2 bits (220), Expect = 2e-18, Method: Composition-based stats. Identities = 47/256 (18%), Positives = 84/256 (32%), Gaps = 44/256 (17%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M + V +V G GIG A+ L + V + Sbjct: 2 MGSDKTVYVVLGGTSGIGAELAKQLESEHTIVHVASRQTG-------------------- 41 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSV-------IS 113 D++D++ + F + G D L+ AG K + + + Sbjct: 42 --LDISDEKSVYHYFETI----GAFDHLIVTAGSYAPAG--KVVDVEVTQAKYAFDTKFW 93 Query: 114 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 173 G L + + +GG I S + VA V A I T+ LA L Sbjct: 94 GAVLAAKH-GARYLKQGGSITLTSGMLSRKVVANTYVKAAINAAIEATTK--VLAKELAP 150 Query: 174 SGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLI 233 +R+NAI PG T + + ++ Y + H+ + + IA + I Sbjct: 151 --IRVNAISPGLTKTEAYKGMNADDRDAMYQRTQSHL----PVGKVGEASDIAMAYLFAI 204 Query: 234 EDDALNGAIMKITTSK 249 ++ + G ++ + Sbjct: 205 QNSYMTGTVIDVDGGA 220 >5TQV-A nrPDB Length = 233 Score = 88.4 bits (218), Expect = 3e-18, Method: Composition-based stats. Identities = 37/218 (16%), Positives = 72/218 (33%), Gaps = 25/218 (11%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 K L+ GA++G+GR F G V + + +A D+ Sbjct: 10 KTVLIVGASRGLGREFVRQYQRDGWNVIATARDDASLAALRAL--------GAHAHALDI 61 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNN----------EKNWEKTLQINLVSVISGT 115 +Q+ K+ RLD+ V +GV +++ + N+ + Sbjct: 62 TQPEQIAALGWKLDGE--RLDVAVVVSGVYGPRTEGVETIASDDFDTVMHTNVRGPMQLL 119 Query: 116 YLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSG 175 + L + G + M S++ +Y ASK + R A+L Sbjct: 120 PILLPLVEDARGVLAVVSSRMGSISEATGTTGW-LYRASKAALNDVLRIASL----QTRH 174 Query: 176 VRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDM 213 ++ PG+V T + + + + I + Sbjct: 175 AACISLHPGWVRTDMGGAQAALDPATSVTGMRRVIAEA 212 >4Q9N-A nrPDB Length = 298 Score = 83.8 bits (206), Expect = 7e-17, Method: Composition-based stats. Identities = 53/297 (17%), Positives = 97/297 (32%), Gaps = 59/297 (19%) Query: 1 MHVNGKVALVTGAA--QGIGRAFAEALLLKGAKVA---------LVDWNLEAG---VQCK 46 + + GK+A + G G G A+ L GA + + +LE G + Sbjct: 4 IDLTGKIAFIAGIGDDNGYGWGIAKMLAEAGATILVGTWVPIYKIFSQSLELGKFNASRE 63 Query: 47 AALDEQFEPQKTLFIQCDVADQQQ------------------LRDTFRKVVDHFGRLDIL 88 + E K + + + + +V HFG +DIL Sbjct: 64 LSNGELLTFAKIYPMDASFDTPEDIPQEILENKRYKDLSGYTVSEVVEQVKKHFGHIDIL 123 Query: 89 VNNAG----------VNNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSS 138 V++ + K + L + S IS M+ G I+++ Sbjct: 124 VHSLANSPEIAKPLLDTSRKGYLAALSTSSYSFISLLSHFGPIMNA-----GASTISLTY 178 Query: 139 LAGLMPVAQQ-PVYCASKHGIVGFTRSAALAANLMNS-GVRLNAICPGFVNTAILESIEK 196 LA + V A+K + T+ LA GVR+N I G + + ++I Sbjct: 179 LASMRAVPGYGGGMNAAKAALESDTK--VLAWEAGRRWGVRVNTISAGPLASRAGKAIGF 236 Query: 197 EENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIED--DALNGAIMKITTSKGI 251 E M D+ +D ++ + L+ A+ G + + + Sbjct: 237 IERM------VDYYQDWAPLPSPMEAEQVGAAAAFLVSPLASAITGETLYVDHGANV 287 >1FJH-A nrPDB Length = 257 Score = 83.0 bits (204), Expect = 1e-16, Method: Composition-based stats. Identities = 49/274 (17%), Positives = 90/274 (32%), Gaps = 61/274 (22%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVA 66 + +++G A GIG A + L G ++ +D + D++ Sbjct: 3 IIVISGCATGIGAATRKVLEAAGHQIVGIDIRDAE-------------------VIADLS 43 Query: 67 DQQQLRDTFRKVVDHF-GRLDILVNNAGVNNEKNW-EKTLQINLVSVISGTYLGLDYMSK 124 + + V+ +D LV AG+ + + +N L + K Sbjct: 44 TAEGRKQAIADVLAKCSKGMDGLVLCAGLGPQTKVLGNVVSVNYFGATELMDAFLPALKK 103 Query: 125 QNGGEGGIIINMSSLA----GLMPVA------------------------QQPVYCASKH 156 G + +SS+A Y SK+ Sbjct: 104 ---GHQPAAVVISSVASAHLAFDKNPLALALEAGEEAKARAIVEHAGEQGGNLAYAGSKN 160 Query: 157 GIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKY 216 + R A A +GVRLN I PG T +L++ ++ G+ I K + Sbjct: 161 ALTVAVRKRAAA--WGEAGVRLNTIAPGATETPLLQAGLQDPRYGESIA-----KFVPPM 213 Query: 217 YGILDPPLIANGLITLIEDDA--LNGAIMKITTS 248 +P +A+ + L+ A ++GA + I Sbjct: 214 GRRAEPSEMASVIAFLMSPAASYVHGAQIVIDGG 247 >2NTV-A nrPDB Length = 268 Score = 78.0 bits (191), Expect = 4e-15, Method: Composition-based stats. Identities = 54/276 (19%), Positives = 94/276 (34%), Gaps = 37/276 (13%) Query: 3 VNGKVALVTG--AAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + GK LV+G I A+ GA++ L ++ +Q A P K Sbjct: 4 LEGKRILVSGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLIQRIADRL----PDKAPL 59 Query: 61 IQCDVADQQQLRDTFRKVVDHFG---RLDILVNNAGVNNE-------------KNWEKTL 104 I+ DV +++ L +V G +LD +V++ G + ++ K + Sbjct: 60 IELDVQNEEHLATLAERVTAEIGEGNKLDGVVHSIGFMPQTGMGTNQFFDAPYEDVSKGI 119 Query: 105 QINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRS 164 I+ S S L M GG I+ M + +K + R Sbjct: 120 HISTYSYASLAKALLLIM-----NSGGSIVGM-DFDPTRAMPAYNWMTVAKSALESVNR- 172 Query: 165 AALAANLMNSGVRLNAICPGFVNTAILESIE----KEENMGQYIEYKDHIKDMIKYY-GI 219 +A GVR N + G + T + +I EE Q ++ + Sbjct: 173 -FVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGAFGEEAGAQMQLLEEGWDQRAPIGWNM 231 Query: 220 LDPPLIANGLITLIED--DALNGAIMKITTSKGIHF 253 DP +A + L+ + A G+I+ Sbjct: 232 KDPTPVAKTVCALLSEWLPATTGSIIYADGGASTQL 267 >1ENP-A nrPDB Length = 312 Score = 76.9 bits (188), Expect = 8e-15, Method: Composition-based stats. Identities = 50/293 (17%), Positives = 98/293 (33%), Gaps = 57/293 (19%) Query: 1 MHVNGKVALVTGAA--QGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKT 58 + + GK A + G A G G A A++L GA++ + W + + +F+ + Sbjct: 14 IDLRGKRAFIAGIADDNGYGWAVAKSLAAAGAEILVGTWVPALNIFETSLRRGKFDQSRV 73 Query: 59 LF----------------------IQCDV--------ADQQQLRDTFRKVVDHFGRLDIL 88 L + DV + +++ V FG +DIL Sbjct: 74 LPDGSLMEIKKVYPLDAVFDNPEDVPEDVKANKRYAGSSNWTVQEAAECVRQDFGSIDIL 133 Query: 89 VNNAG----------VNNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSS 138 V++ + K + + + S +S L M GG I+++ Sbjct: 134 VHSLANGPEVSKPLLETSRKGYLAAISASSYSFVSLLSHFLPIM-----NPGGASISLTY 188 Query: 139 LAGLMPVAQQ-PVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKE 197 +A + ++K + TR A A +R+N I G + + ++I Sbjct: 189 IASERIIPGYGGGMSSAKAALESDTRVLAFEAG-RKQNIRVNTISAGPLGSRAAKAI--- 244 Query: 198 ENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIED--DALNGAIMKITTS 248 G ++ + L + N L+ A+ GA + + Sbjct: 245 ---GFIDTMIEYSYNNAPIQKTLTADEVGNAAAFLVSPLASAITGATIYVDNG 294 >4OYR-A nrPDB Length = 289 Score = 75.3 bits (184), Expect = 3e-14, Method: Composition-based stats. Identities = 55/277 (19%), Positives = 95/277 (34%), Gaps = 39/277 (14%) Query: 3 VNGKVALVTG--AAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 ++GK LV+G I A +GA++ L ++ +Q P K Sbjct: 25 LDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRL----PAKAPL 80 Query: 61 IQCDVADQQQLRDTFRKVVDHFG---RLDILVNNAGVNNE-------------KNWEKTL 104 ++ DV +++ L +V + G +LD +V++ G + + K + Sbjct: 81 LELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGI 140 Query: 105 QINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRS 164 I+ S S L M GG I+ M + +K + R Sbjct: 141 HISAYSYASMAKALLPIM-----NPGGSIVGM-DFDPSRAMPAYNWMTVAKSALESVNR- 193 Query: 165 AALAANLMNSGVRLNAICPGFVNTAILESI----EKEENMGQYIEYKDHIKDMIKYY-GI 219 +A GVR N + G + T + +I EE Q ++ + Sbjct: 194 -FVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNM 252 Query: 220 LDPPLIANGLITLIED--DALNGAIMKITTSKGIHFQ 254 D +A + L+ D A G I+ G H Q Sbjct: 253 KDATPVAKTVCALLSDWLPATTGDIIYADG--GAHTQ 287 >2PTG-A nrPDB Length = 319 Score = 73.0 bits (178), Expect = 1e-13, Method: Composition-based stats. Identities = 53/321 (16%), Positives = 102/321 (31%), Gaps = 69/321 (21%) Query: 2 HVNGKVALVTGA--AQGIGRAFAEALLLKGAKVALVDW---------------------- 37 + GK A V G + G G A + L GA+V + W Sbjct: 6 DLRGKTAFVAGVADSNGYGWAICKLLRAAGARVLVGTWPPVYSIFKKGLESSRFEQDSFY 65 Query: 38 --------NLEAGVQCKAALDEQFEPQKTLF-----IQCDVADQQ--------QLRDTFR 76 EA + + ++ P +F + +V+ + + + Sbjct: 66 AQEPSSKVAAEAAEKPVDLVFDKIYPLDAVFDTPQDVPPEVSSNKRYAGVGGFTISEVAE 125 Query: 77 KVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVIS-----------GTYLGLDYMSKQ 125 V G++DILV++ N + + LQ + ++ L M + Sbjct: 126 AVRADVGQIDILVHSLA-NGPEVTKPLLQTSRKGYLAAVSSSSYSFVSLLQHFLPLMKE- 183 Query: 126 NGGEGGIIINMSSLAGLMPVAQQPV-YCASKHGIVGFTRSAALAANLMNSGVRLNAICPG 184 GG + +S +A + ++K + R+ A A + VR+N I G Sbjct: 184 ----GGSALALSYIASEKVIPGYGGGMSSAKAALESDCRTLAFEAGRARA-VRVNCISAG 238 Query: 185 FVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIED--DALNGAI 242 + + +I K + D+ + L+ + + L+ A+ GA Sbjct: 239 PLKSRAASAIGKAGDKTFIDLAIDYSEANAPLQKELESDDVGRAALFLLSPLARAVTGAT 298 Query: 243 MKITTS---KGIHFQDYDTTP 260 + + G TP Sbjct: 299 LYVDNGLHAMGQALDSKSLTP 319 >3SLK-A nrPDB Length = 795 Score = 65.7 bits (159), Expect = 2e-11, Method: Composition-based stats. Identities = 34/160 (21%), Positives = 64/160 (40%), Gaps = 5/160 (3%) Query: 7 VALVTGAAQGIGRAFAEALL-LKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQ-C 63 LVTG +G A L+ +G + + LV A + + + +Q C Sbjct: 532 TVLVTGGTGALGAEVARHLVIERGVRNLVLVSRRGPAASGAAELVAQLTAYGAEVSLQAC 591 Query: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMS 123 DVAD++ L + D L +V+ AGV ++ E L V+ G + Sbjct: 592 DVADRETLAKVLASIPDEH-PLTAVVHAAGVLDDGVSESLTVERLDQVLRPKVDGARNLL 650 Query: 124 KQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTR 163 + + +++ SS++G++ Q Y A+ + + Sbjct: 651 ELIDPDVALVLF-SSVSGVLGSGGQGNYAAANSFLDALAQ 689 >4LIS-A nrPDB Length = 371 Score = 64.5 bits (156), Expect = 5e-11, Method: Composition-based stats. Identities = 36/171 (21%), Positives = 55/171 (32%), Gaps = 31/171 (18%) Query: 8 ALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVAD 67 LVTG IG ALL G KV + D NL E +K F Q DV D Sbjct: 6 VLVTGGTGYIGSFTTLALLEAGYKVVVAD-NLYNSSAEALNRIELISGKKAEFAQLDVTD 64 Query: 68 QQQLRDTFRKVVDHFGRLDILVNNAGV----NNEKNWEKTLQINLVSVISGTYLGLDYMS 123 F KV + +D +++ A + + + +N+ I + + Sbjct: 65 ----EAAFDKVFEAHPDIDSVIHFAALKAVGESGEKPLDYYHVNVYGTICLLRSMVRH-- 118 Query: 124 KQNGGEGGIIINMSSLAGL---------MPVAQQ------PVYCASKHGIV 159 I+ SS +P+ + Y +K I Sbjct: 119 -----NVTNIVFSSSATVYGDATRFPDMIPIPEHCPLGPTNPYGNTKFAIE 164 >3F4B-A nrPDB Length = 323 Score = 61.9 bits (149), Expect = 3e-10, Method: Composition-based stats. Identities = 45/304 (14%), Positives = 94/304 (30%), Gaps = 69/304 (22%) Query: 12 GAAQGIGRAFAEALLLKGAKVALVDW---------NLEAGVQCKAALDEQFEPQK---TL 59 G + G G A+ L + KV W NLE+G K + ++ Sbjct: 16 GDSNGYGWGIAKELSKRNVKVIFGVWPPVYNIFIKNLESGKFDKDMIINNDNSKRMQILD 75 Query: 60 FIQCDVA-------DQQ-------------QLRDTFRKVVDHFGRLDILVNNAG------ 93 + D D+ + + + + +G++ +LV++ Sbjct: 76 VLPLDAGFDNYDDIDEDTKNNKRYNNLKNYSIEEVANLIYNKYGKISMLVHSLANGREVQ 135 Query: 94 ----VNNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQP 149 + + + + S+IS +M GG +++++ A V Sbjct: 136 KSLLDTSRDGYLDAISKSSYSLISLCKHFCKFM-----NSGGSVVSLTYQASQKVVPGYG 190 Query: 150 V-YCASKHGIVGFTRSAALAANLMN-SGVRLNAICPGFVNTAILESI------------- 194 ++K + TR LA L +R+N I G + + +I Sbjct: 191 GGMSSAKAALESDTR--VLAYYLGRKYNIRINTISAGPLKSRAATAINKFNNNQKNNMNS 248 Query: 195 ---EKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDD--ALNGAIMKITTSK 249 ++N D+ + L + + L+ + A+ G + + Sbjct: 249 SGETDKQNYSFIDYAIDYSEKYAPLKKKLLSTDVGSVASFLLSKESSAVTGQTIYVDNGL 308 Query: 250 GIHF 253 I F Sbjct: 309 NIMF 312 >2PK3-A nrPDB Length = 321 Score = 60.7 bits (146), Expect = 6e-10, Method: Composition-based stats. Identities = 47/271 (17%), Positives = 84/271 (30%), Gaps = 48/271 (17%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVA 66 AL+TG A +G+ A L + +V N EA + I D+ Sbjct: 14 RALITGVAGFVGKYLANHLTEQNVEVFGTSRNNEAKLP------------NVEMISLDIM 61 Query: 67 DQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKN-W---EKTLQINLVSVISGTYLGLDYM 122 D Q+++ + + D + + A ++ K+ W + T N+ + Sbjct: 62 DSQRVKKVISDI-----KPDYIFHLAAKSSVKDSWLNKKGTFSTNVFGTLHVLDAV---- 112 Query: 123 SKQNGGEGGIIINMSS-------------LAGLMPVAQQPVYCASKHGIVGFTRSAALAA 169 ++ I+ + S ++ + Y SK + R A Sbjct: 113 --RDSNLDCRILTIGSSEEYGMILPEESPVSEENQLRPMSPYGVSKASVGMLARQYVKAY 170 Query: 170 NLMNSGVR-LNAICP----GFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPL 224 + R N I P GFV + I E Q E + ++ D Sbjct: 171 GMDIIHTRTFNHIGPGQSLGFVTQDFAKQIVDIEMEKQ--EPIIKVGNLEAVRDFTDVRD 228 Query: 225 IANGLITLIEDDALNGAIMKITTSKGIHFQD 255 I L+ G + + + G QD Sbjct: 229 IVQAYW-LLSQYGKTGDVYNVCSGIGTRIQD 258 >3ORF-A nrPDB Length = 251 Score = 59.9 bits (144), Expect = 1e-09, Method: Composition-based stats. Identities = 33/243 (13%), Positives = 76/243 (31%), Gaps = 28/243 (11%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 K LV G + +G + K +D+ + + E Sbjct: 23 KNILVLGGSGALGAEVVKFFKSKSWNTISIDFRENPNADHSFTIKDSGE----------- 71 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNN---------EKNWEKTLQINLVSVISGTY 116 ++++ K+ ++D V AG + K+ + + +NL S + + Sbjct: 72 ---EEIKSVIEKINSKSIKVDTFVCAAGGWSGGNASSDEFLKSVKGMIDMNLYSAFASAH 128 Query: 117 LGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGV 176 +G + +GG+ + + A L + Y A+K + A + +G Sbjct: 129 IGAKLL-----NQGGLFVLTGASAALNRTSGMIAYGATKAATHHIIKDLASENGGLPAGS 183 Query: 177 RLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDD 236 I P ++T + N + + + + ++ D L+ Sbjct: 184 TSLGILPVTLDTPTNRKYMSDANFDDWTPLSEVAEKLFEWSTNSDSRPTNGSLVKFETKS 243 Query: 237 ALN 239 + Sbjct: 244 KVT 246 >3RFT-A nrPDB Length = 267 Score = 55.7 bits (133), Expect = 2e-08, Method: Composition-based stats. Identities = 36/162 (22%), Positives = 59/162 (36%), Gaps = 37/162 (22%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 K LVTGAA +GR E L + L D + LD ++ +QCD+ Sbjct: 4 KRLLVTGAAGQLGRVMRERLAPMAEILRLADLSP---------LDPAGPNEEC--VQCDL 52 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMSKQ 125 AD + D +V+ G++ EK +E+ LQ N++ + + + + Sbjct: 53 ADANAVNAMVA-------GCDGIVHLGGISVEKPFEQILQGNIIGLYNLYEAARAHGQPR 105 Query: 126 NGGEGGIIINMSSLAGLMPVAQQ------------PVYCASK 155 I+ SS + Q +Y SK Sbjct: 106 -------IVFASSNHTIGYYPQTERLGPDVPARPDGLYGVSK 140 >1UDA-A nrPDB Length = 338 Score = 54.9 bits (131), Expect = 3e-08, Method: Composition-based stats. Identities = 25/163 (15%), Positives = 53/163 (32%), Gaps = 15/163 (9%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVA 66 LVTG + IG LL G V ++D NL + + E+ + F++ D+ Sbjct: 2 RVLVTGGSGYIGSHTCVQLLQNGHDVIILD-NLCNSKRSVLPVIERLGGKHPTFVEGDIR 60 Query: 67 DQQQLRDTFRKVVDHFGRLDILVNNAGV----NNEKNWEKTLQINLVSVISGTYLGLDYM 122 + +++ +D +++ AG+ + + + N+ + Sbjct: 61 N----EALMTEILHDHA-IDTVIHFAGLKAVGESVQKPLEYYDNNVNGTLRLISAMRAAN 115 Query: 123 SKQNGGEGGIIIN-----MSSLAGLMPVAQQPVYCASKHGIVG 160 K + + + Q Y SK + Sbjct: 116 VKNFIFSSSATVYGDNPKIPYVESFPTGTPQSPYGKSKLMVEQ 158 >1OOE-A nrPDB Length = 236 Score = 54.5 bits (130), Expect = 4e-08, Method: Composition-based stats. Identities = 34/241 (14%), Positives = 79/241 (32%), Gaps = 21/241 (8%) Query: 4 NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63 +GKV +V G +G A E G V ++ +L A Q + + T Sbjct: 3 SGKV-IVYGGKGALGSAILEFFKKNGYTV--LNIDLSANDQADSNILVDGNKNWT----- 54 Query: 64 DVADQQQLRDTFRKVVDHFGR--LDILVNNAG-----VNNEKNWEKTLQINLVSVISGTY 116 +Q + + +D + AG + K++ K + + + + Sbjct: 55 -----EQEQSILEQTASSLQGSQVDGVFCVAGGWAGGSASSKDFVKNADLMIKQSVWSSA 109 Query: 117 LGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGV 176 + + GG++ + A + P Y +K + T S A + + Sbjct: 110 IAAKLATTHL-KPGGLLQLTGAAAAMGPTPSMIGYGMAKAAVHHLTSSLAAKDSGLPDNS 168 Query: 177 RLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDD 236 + I P ++T + + + + ++K+ + L+ + ++ Sbjct: 169 AVLTIMPVTLDTPMNRKWMPNADHSSWTPLSFISEHLLKWTTETSSRPSSGALLKITTEN 228 Query: 237 A 237 Sbjct: 229 G 229 >2O2Y-A nrPDB Length = 349 Score = 54.1 bits (129), Expect = 6e-08, Method: Composition-based stats. Identities = 46/265 (17%), Positives = 88/265 (33%), Gaps = 62/265 (23%) Query: 40 EAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVN---NAGV-- 94 +A +DE+ + K + ++ + D + +G++++LV+ NA Sbjct: 85 DASFDTANDIDEETKNNK----RYNMLQNYTIEDVANLIHQKYGKINMLVHSLANAKEVQ 140 Query: 95 -----NNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQP 149 + K + L + S+IS ++ M Q+ II+++ A V Sbjct: 141 KDLLNTSRKGYLDALSKSSYSLISLCKYFVNIMKPQS-----SIISLTYHASQKVVPGYG 195 Query: 150 V-YCASKHGIVGFTRSAALAANLMN-SGVRLNAICPGFVNTA------------------ 189 ++K + TR LA +L +R+N I G + + Sbjct: 196 GGMSSAKAALESDTR--VLAYHLGRNYNIRINTISAGPLKSRAATAINKLNNTYENNTNQ 253 Query: 190 ------------ILESIEKEENMGQYIEYKDHIKDMIKYYGILDP-------PLIANGLI 230 + S EKEE + I I+Y P I + Sbjct: 254 NKNRNSHDVHNIMNNSGEKEEKKNSASQNYTFIDYAIEYSEKYAPLRQKLLSTDIGSVAS 313 Query: 231 TLIEDD--ALNGAIMKITTSKGIHF 253 L+ + A+ G + + I F Sbjct: 314 FLLSRESRAITGQTIYVDNGLNIMF 338 >3ENK-A nrPDB Length = 341 Score = 53.4 bits (127), Expect = 1e-07, Method: Composition-based stats. Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 2/77 (2%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M G LVTG A IG A LL G V + D NL + A E+ + F Sbjct: 2 MSTKG-TILVTGGAGYIGSHTAVELLAHGYDVVIAD-NLVNSKREAIARIEKITGKTPAF 59 Query: 61 IQCDVADQQQLRDTFRK 77 + DV+D++ L F Sbjct: 60 HETDVSDERALARIFDA 76 >6BWL-A nrPDB Length = 328 Score = 49.9 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 37/183 (20%), Positives = 63/183 (34%), Gaps = 10/183 (5%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVA 66 LVTG A IGR + LL +V ++D A + + IQ D+ Sbjct: 2 KILVTGGAGFIGRWVVKRLLQDKHEVWILD--NLANSTTANITEFAHDLNLKQCIQGDIK 59 Query: 67 DQQQLRDTFRKVVDHFGRLDILVNNAGVNNE-KNWEKTLQINLVSVISGTYLGLDYMSKQ 125 D++ + F + F L + V + + T + + + + L+Y K Sbjct: 60 DKKLVAQLFEN--NSFDLCYHLAASINVQDSIDDARATFENDTIGTFNLLEQCLNYDVKM 117 Query: 126 NGGEGGII----INMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR-LNA 180 ++ N+ ++ L P+ Y SK S A L +R N Sbjct: 118 VFMSTCMVYDKATNIQGISELDPIKPASPYAGSKIAAENMVLSYYYAYKLPVVVIRPFNT 177 Query: 181 ICP 183 P Sbjct: 178 YGP 180 >1DIR-A nrPDB Length = 241 Score = 49.9 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 34/217 (15%), Positives = 76/217 (35%), Gaps = 36/217 (16%) Query: 4 NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63 + LV G +G +A + VA +D + E E ++ ++ Sbjct: 6 EARRVLVYGGRGALGSRCVQAFRARNWWVASID------------VVENEEASASVIVKM 53 Query: 64 DVADQQQLRDTFRKVVDHFG--RLDILVNNAGVNN-------------EKNWEKTLQINL 108 + +Q +V G ++D ++ AG + W++++ + Sbjct: 54 TDSFTEQADQVTAEVGKLLGDQKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSIWTST 113 Query: 109 VSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALA 168 +S ++L ++ + GG++ + A L Y +K + +S A Sbjct: 114 IS----SHLATKHLKE-----GGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGK 164 Query: 169 ANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIE 205 + M SG A+ P ++T + E + + Sbjct: 165 NSGMPSGAAAIAVLPVTLDTPMNRKSMPEADFSSWTP 201 >2NNL-D nrPDB Length = 337 Score = 49.1 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 47/264 (17%), Positives = 75/264 (28%), Gaps = 33/264 (12%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 M + VTGA+ IG LL +G V + + K LD Sbjct: 1 MGSQSETVCVTGASGFIGSWLVMRLLERGYTVRATVRDPTNVKKVKHLLDLPKAETHLTL 60 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLD 120 + D+AD+ + + F V ++E N VI T G+ Sbjct: 61 WKADLADEGSFDEAIKGCTGVFH----------VATPMDFESKDPEN--EVIKPTIEGML 108 Query: 121 YMSKQ--NGGEGGIIINMSSLAGLMPVAQQ-PVYC-----------ASKHGIVGFTRSAA 166 + K ++ SS + Q PVY A K + S Sbjct: 109 GIMKSCAAAKTVRRLVFTSSAGTVNIQEHQLPVYDESCWSDMEFCRAKKMTAWMYFVSKT 168 Query: 167 LAANLM-----NSGVRLNAICPGFVNTA--ILESIEKEENMGQYIEYKDHIKDMIKYYGI 219 LA + + I P V + I + +I+ Sbjct: 169 LAEQAAWKYAKENNIDFITIIPTLVVGPFIMSSMPPSLITALSPITGNEAHYSIIRQGQF 228 Query: 220 LDPPLIANGLITLIEDDALNGAIM 243 + + N I L E+ G + Sbjct: 229 VHLDDLCNAHIYLFENPKAEGRYI 252 >1Z45-A nrPDB Length = 699 Score = 49.1 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 23/91 (25%), Positives = 38/91 (41%), Gaps = 6/91 (6%) Query: 4 NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63 K+ LVTG A IG L+ G + D NL A E F + Sbjct: 10 TSKIVLVTGGAGYIGSHTVVELIENGYDCVVAD-NLSNSTYDSVARLEVLTKHHIPFYEV 68 Query: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGV 94 D+ D++ L F++ ++D +++ AG+ Sbjct: 69 DLCDRKGLEKVFKEY-----KIDSVIHFAGL 94 >4R1T-A nrPDB Length = 337 Score = 47.2 bits (111), Expect = 7e-06, Method: Composition-based stats. Identities = 44/269 (16%), Positives = 84/269 (31%), Gaps = 53/269 (19%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 V+G+V VTGA I + LL KG V N + + + + ++ Sbjct: 7 SVSGQVVCVTGAGGFIASWLVKILLEKGYTVRGTVRNPDD-PKNGHLRELEGAKERLTLC 65 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDY 121 + D+ D Q LR+ D + + A + + E+ ++ ++ + + Sbjct: 66 KADLLDYQSLREAIN-------GCDGVFHTASPVTD-DPEQMVEPAVIGTKNVINAAAEA 117 Query: 122 MSKQNGGEGGIIINMSSLAGLMPVAQQPV---------------------YCASKHGIVG 160 ++ ++ SS+ + + YC K Sbjct: 118 NVRR-------VVFTSSIGAVYMDPNRDPETVVDETCWSDPDFCKNTKNWYCYGK----- 165 Query: 161 FTRSAALAANLMN-SGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYY-- 217 A A GV L I P V +L++ + ++ K Y Sbjct: 166 MVAEQA-AWEEAKEKGVDLVVINPVLVQGPLLQTTVN----ASVLHILKYLTGSAKTYAN 220 Query: 218 ---GILDPPLIANGLITLIEDDALNGAIM 243 +D +A I L E +G + Sbjct: 221 SVQAYVDVKDVALAHILLYETPEASGRYL 249 >1I3M-A nrPDB Length = 348 Score = 47.2 bits (111), Expect = 8e-06, Method: Composition-based stats. Identities = 41/184 (22%), Positives = 61/184 (33%), Gaps = 35/184 (19%) Query: 7 VALVTGAAQGIGRAFAEALLLKGA-KVALVDWNLE--AGVQCKAALD--EQFEPQKTLFI 61 LVTG A IG LL G V + +++ G +L ++ + F Sbjct: 4 KVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFE 63 Query: 62 QCDVADQQQLRDTFRK----VVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYL 117 + D+ DQ L+ F+K V HF L A + + ++NL I Sbjct: 64 EMDILDQGALQRLFKKYSFMAVIHFAGLK-----AMGESVQKPLDYYRVNLTGTIQL--- 115 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQ-------------PVYCASKHGIVGFTRS 164 L+ M G ++ SS A + Q Y SK I R Sbjct: 116 -LEIMKAH--GVKNLVF--SSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRD 170 Query: 165 AALA 168 A Sbjct: 171 LCQA 174 >5B6K-A nrPDB Length = 366 Score = 45.7 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 26/138 (18%), Positives = 51/138 (36%), Gaps = 8/138 (5%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVA 66 V+GA I + LL + KV + E G K + + I D++ Sbjct: 23 TVFVSGATGFIAQHVVRQLLDQNYKVIGSVRSAEKGDHLKNVIFK--GGDFNYEIVKDIS 80 Query: 67 DQQQLRDTFRKVVDHFGR-LDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMSKQ 125 D F V + G+ + ++++ A + + + L+ ++GT L+ + K Sbjct: 81 DPT----AFDHVFEKHGKDIKVVLHTASPFHFNTTDIEKDL-LIPAVNGTKGILESIKKY 135 Query: 126 NGGEGGIIINMSSLAGLM 143 ++ SS A Sbjct: 136 AAQTVERVVVTSSFAANT 153 >2HUN-A nrPDB Length = 336 Score = 44.9 bits (105), Expect = 4e-05, Method: Composition-based stats. Identities = 38/175 (21%), Positives = 75/175 (42%), Gaps = 26/175 (14%) Query: 9 LVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQ 68 LVTG IG F +L K +++ + A L + + + F++ DVAD Sbjct: 7 LVTGGMGFIGSNFIRYILEKHPDWEVINIDKLGYGSNPANLKDLEDDPRYTFVKGDVADY 66 Query: 69 QQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTL---QINLVSVISGTYLGLDYMSKQ 125 + +++ RK +D +V+ A E + ++++ +I L S + GTY L+ + ++ Sbjct: 67 ELVKELVRK-------VDGVVHLAA---ESHVDRSISSPEIFLHSNVIGTYTLLESIRRE 116 Query: 126 NGGEGGIIINM---------SSLAGLMPVAQQPVYCASKHG----IVGFTRSAAL 167 N + ++ S + Y A+K ++G+TR+ L Sbjct: 117 NPEVRFVHVSTDEVYGDILKGSFTENDRLMPSSPYSATKAASDMLVLGWTRTYNL 171 >5K1S-A nrPDB Length = 362 Score = 44.5 bits (104), Expect = 5e-05, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 33/79 (41%), Gaps = 1/79 (1%) Query: 5 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64 G+ L+TGA+ G+G + + L GA+V V + K A ++ + L D Sbjct: 184 GETVLITGASGGVGLSSVQLARLDGARVIAVTSSEAKVQALKEAGADEVIVSRGLDFASD 243 Query: 65 VADQQQLRDTFRKVVDHFG 83 V + Q V+ G Sbjct: 244 VRKRTQ-GAGVDVAVEIVG 261 >2GN9-A nrPDB Length = 344 Score = 44.1 bits (103), Expect = 6e-05, Method: Composition-based stats. Identities = 30/158 (18%), Positives = 60/158 (37%), Gaps = 25/158 (15%) Query: 3 VNGKVALVTGAAQGIGRAFAEA-LLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 ++ + L+TG G+ F L AK +V E ++ + +F + F Sbjct: 19 LDNQTILITGGTGSFGKCFVRKVLDTTNAKKIIVYSRDEL---KQSEMAMEFNDPRMRFF 75 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN----EKNWEKTLQINLVSVISGTYL 117 DV D ++L +DI ++ A + + E N + ++ N++ + Sbjct: 76 IGDVRDLERLNYALE-------GVDICIHAAALKHVPIAEYNPLECIKTNIMGASNVINA 128 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASK 155 L Q +I +S+ P+ +Y A+K Sbjct: 129 CLKNAISQ-------VIALSTDKAANPI---NLYGATK 156 >1ZZE-A nrPDB Length = 342 Score = 43.7 bits (102), Expect = 8e-05, Method: Composition-based stats. Identities = 23/144 (15%), Positives = 49/144 (34%), Gaps = 11/144 (7%) Query: 4 NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63 G + LVTGA + E LL G KV + + D ++ + + Sbjct: 10 EGSLVLVTGANGFVASHVVEQLLEHGYKVRGTARSASKLANLQKRWDAKYPGRFETAVVE 69 Query: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMS 123 D+ + + +V+ + A + + ++ + I GT L + Sbjct: 70 DMLK----QGAYDEVIKGAAGV------AHIASVVSFSNKYDEVVTPAIGGTLNALRAAA 119 Query: 124 KQNGGEGGIIINMSSLAGLMPVAQ 147 ++ S+++ L+P Sbjct: 120 AT-PSVKRFVLTSSTVSALIPKPN 142 >2Z95-A nrPDB Length = 345 Score = 43.0 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 32/77 (41%), Gaps = 4/77 (5%) Query: 3 VNGKVALVTGAAQGI-GRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 ++GK AL+TG +G G A+ LL KG +V D + L E I Sbjct: 1 MSGKRALITG-IRGQDGAYLAKLLLEKGYEVYGADRRSGEFASWR--LKELGIENDVKII 57 Query: 62 QCDVADQQQLRDTFRKV 78 D+ + + T KV Sbjct: 58 HMDLLEFSNIIRTIEKV 74 >2Q1W-A nrPDB Length = 333 Score = 42.6 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 24/116 (20%), Positives = 41/116 (35%), Gaps = 12/116 (10%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 K +TG IG AE LL +G KV +D N G + + + F++ + Sbjct: 22 KKVFITGICGQIGSHIAELLLERGDKVVGID-NFATGRR-----EHLKDHPNLTFVEGSI 75 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE-KNWEKTLQINLVSVISGTYLGLD 120 AD + + + D +V+ A + +W N V + Sbjct: 76 ADHALVNQLIGDL-----QPDAVVHTAASYKDPDDWYNDTLTNCVGGSNVVQAAKK 126 >4G5H-A nrPDB Length = 363 Score = 42.6 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 39/274 (14%), Positives = 79/274 (28%), Gaps = 66/274 (24%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTL 59 M + K+ L+TG G A + L K + + + + + + +++ K Sbjct: 21 MGFDDKILLITGGTGSFGNAVMKRFLDSNIKEIRIFSRDEKK----QDDIRKKYNNSKLK 76 Query: 60 FIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAG-------------------VNNEKNW 100 F DV D Q + R +D + + A + E Sbjct: 77 FYIGDVRDSQSVETAMRD-------VDYVFHAAALKQVPSCEFFPVEAVKTNIIGTENVL 129 Query: 101 EKTLQINLVSVISGT--YLGLD---------YMSKQNGGEGGIIINMSSLAGLMPVAQQP 149 + + N+ VI + M K + N+ S L+ + Sbjct: 130 QSAIHQNVKKVICLSTDKAAYPINAMGISKAMMEKVFVAKSR---NIRSEQTLICGTRYG 186 Query: 150 VYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEEN-------MGQ 202 AS+ ++ A + + + + E+ + Sbjct: 187 NVMASRGSVIPLFIDKIKAGE--PLTIT---------DPDMTRFLMSLEDAVELVVHAFK 235 Query: 203 YIEYKDHIKDMIKYYGILDPPLIANGLITLIEDD 236 + E D + + D +A L+ L E D Sbjct: 236 HAETGDIMVQKAPSSTVGD---LATALLELFEAD 266 >6ACF-A nrPDB Length = 367 Score = 41.8 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 27/65 (41%), Gaps = 2/65 (3%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQF-EPQKTLF 60 + GKV V G + L +GAK+ + D N EA + + +P Sbjct: 170 SLEGKVVAVQGVGN-VAYHLCRHLHEEGAKLIVTDINKEAVARAVEEFGAKAVDPNDIYG 228 Query: 61 IQCDV 65 ++CD+ Sbjct: 229 VECDI 233 >1R66-A nrPDB Length = 337 Score = 41.4 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 40/181 (22%), Positives = 64/181 (35%), Gaps = 48/181 (26%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGA-------KVALVDWNLEAGVQCKAALDEQF 53 M + LVTG A IG F LL GA +V ++D AG + A L Sbjct: 1 MRL-----LVTGGAGFIGSHFVRQLL-AGAYPDVPADEVIVLDSLTYAGNR--ANLAPVD 52 Query: 54 EPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTL-------QI 106 + F+ D+ D L R +D +V+ A E + ++++ + Sbjct: 53 ADPRLRFVHGDIRDAGLLARELR-------GVDAIVHFAA---ESHVDRSIAGASVFTET 102 Query: 107 NLVSVISGTYLGLDYMSKQNGGEGGII----------INMSSLAGLMPVAQQPVYCASKH 156 N+ + +D G G ++ I+ S P+ Y ASK Sbjct: 103 NVQGTQTLLQCAVDA------GVGRVVHVSTDEVYGSIDSGSWTESSPLEPNSPYAASKA 156 Query: 157 G 157 G Sbjct: 157 G 157 >3BIC-A nrPDB Length = 762 Score = 41.4 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 15/92 (16%), Positives = 33/92 (35%), Gaps = 3/92 (3%) Query: 21 FAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVVD 80 A G V + + A+D + + + + +++ + Sbjct: 624 IATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAA--GHKTLVPELIKEL-N 680 Query: 81 HFGRLDILVNNAGVNNEKNWEKTLQINLVSVI 112 GR DILV GV +++E ++ + +V Sbjct: 681 SLGRPDILVMCGGVIPPQDYEFLFEVGVSNVF 712 >1GY8-A nrPDB Length = 397 Score = 41.0 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 33/160 (20%), Positives = 51/160 (31%), Gaps = 26/160 (16%) Query: 7 VALVTGAAQGIGRAFAEALLLK-GAKVALVDW------------NLEAGVQCKAALDEQF 53 LV G A IG F ALL V +VD E + D Sbjct: 4 RVLVCGGAGYIGSHFVRALLRDTNHSVVIVDSLVGTHGKSDHVETRENVARKLQQSDGPK 63 Query: 54 EPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVN-NAGVN---NEKNWEKTLQINLV 109 P + +V D + D V G +D +V+ A + + ++ K N+V Sbjct: 64 PPWADRYAALEVGDVRN-EDFLNGVFTRHGPIDAVVHMCAFLAVGESVRDPLKYYDNNVV 122 Query: 110 SVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQP 149 ++ L + + II SS A + Sbjct: 123 GILRLLQAMLLH-------KCDKIIF-SSSAAIFGNPTMG 154 >6GCS-E nrPDB Length = 375 Score = 41.0 bits (95), Expect = 6e-04, Method: Composition-based stats. Identities = 20/118 (16%), Positives = 35/118 (29%), Gaps = 11/118 (9%) Query: 4 NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63 G A V GA +G L G V + K L + F++ Sbjct: 52 TGYTATVFGANGFLGSYLTAKLAKHGTTVVVPYREE----MAKRHLKVTGDLGVVNFLEM 107 Query: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDY 121 D+ + + + + R DI+VN G E +++ + Sbjct: 108 DLRNLESIDEAVRHS-------DIVVNLIGREYETKNFNYYDVHVEGARRIAEAVKKH 158 Score = 34.1 bits (77), Expect = 0.067, Method: Composition-based stats. Identities = 12/86 (13%), Positives = 28/86 (32%), Gaps = 3/86 (3%) Query: 93 GVNNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYC 152 + + + + NL ++ T G ++K GG +++ G Y Sbjct: 13 AITTSVRFMNSFE-NLAQDVNITRSGKTLIAKGTGGRSSRTGYTATVFGANGFLG--SYL 69 Query: 153 ASKHGIVGFTRSAALAANLMNSGVRL 178 +K G T + +++ Sbjct: 70 TAKLAKHGTTVVVPYREEMAKRHLKV 95 >5YWN-A nrPDB Length = 334 Score = 40.7 bits (94), Expect = 7e-04, Method: Composition-based stats. Identities = 42/268 (15%), Positives = 87/268 (32%), Gaps = 39/268 (14%) Query: 8 ALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVAD 67 V+GA + + +L KG KV + E G K + F + V Sbjct: 5 VFVSGATGYLAQQIIALVLSKGYKVVGSVRSEEKGANLKKLYGDDFSYE--------VVK 56 Query: 68 QQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMSKQNG 127 + + F + + + I ++ A + + +I L+ I+GT L + K Sbjct: 57 VLEQKGAFDEALKKHPEVTIFLHTASPVTFEVEDTEKEI-LIPAINGTKYVLQSI-KDVA 114 Query: 128 GEGGIIINMSSLAG-----LMPVAQQPV---------YCASK-HGIVGFTRSAALA---- 168 + ++ SS+ + + Y SK HG++ + S A Sbjct: 115 PQITRVVYTSSVVAMSVPEELGSPDVVLSEASWSSLSYEQSKTHGVLAYFGSKQFAERAA 174 Query: 169 ---ANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIK-------YYG 218 L+ + P ++ + E + + E + + + K Sbjct: 175 WEFVEQEKPNFALSTVNPVYIFGPQAKDEEVKGTLNHSAEMVNSVLKLNKDDDVPATTGT 234 Query: 219 ILDPPLIANGLITLIEDDALNGAIMKIT 246 +D +A + E D G + ++ Sbjct: 235 FIDVRDVAKAHLAAFEKDEAKGERLLLS 262 >4PVC-A nrPDB Length = 342 Score = 40.3 bits (93), Expect = 8e-04, Method: Composition-based stats. Identities = 25/141 (17%), Positives = 52/141 (36%), Gaps = 18/141 (12%) Query: 8 ALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVAD 67 V+GA I + + LL + KV + E A P+ ++ + D++ Sbjct: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGN--NPKFSMEVVPDISK 60 Query: 68 QQQLRDTFRKVVDHFGR-LDILVNNAG-----VNNEKNWEKTLQINLVSVISGTYLGLDY 121 D F V G+ + I+++ A + + + + L+ ++G L Sbjct: 61 L----DAFDHVFQKHGKDIKIVLHTASPFCFDITDSER-----DL-LIPAVNGVKGILHS 110 Query: 122 MSKQNGGEGGIIINMSSLAGL 142 + K ++ SS A + Sbjct: 111 IKKYAADSVERVVLTSSYAAV 131 >5N2I-A nrPDB Length = 232 Score = 40.3 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 19/56 (33%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQK 57 V+G V G GR A + G +V L + E A L E + Sbjct: 16 DVSGLSIAVLGGTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAELGEGLPVRG 71 >2PZM-A nrPDB Length = 330 Score = 39.9 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 29/165 (17%), Positives = 50/165 (30%), Gaps = 26/165 (15%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVA 66 L+TG A +G E L +G ++ ++D + + I+ V Sbjct: 22 RILITGGAGCLGSNLIEHWLPQGHEILVIDNFATGKREVLPPVA------GLSVIEGSVT 75 Query: 67 DQQQLRDTFRKVVDHFGRLDILVNNAGVNNE-KNWEKTLQINLVSVISGTYLGLDYMSKQ 125 D L F +V++A + +W + N+ I+ K+ Sbjct: 76 DAGLLERAFDSFKPTH-----VVHSAAAYKDPDDWAEDAATNVQGSINVAKAASKAGVKR 130 Query: 126 N--------GGEGGII-INMSSLAGLMPVAQQPVYCASKHGIVGF 161 G + I + S P A Y SK F Sbjct: 131 LLNFQTALCYGRPATVPIPIDS-----PTAPFTSYGISKTAGEAF 170 >1LU9-A nrPDB Length = 287 Score = 39.9 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 30/70 (42%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 V GK A+V +G A L +GA+V L L+ +++++F+ T Sbjct: 116 SVKGKKAVVLAGTGPVGMRSAALLAGEGAEVVLCGRKLDKAQAAADSVNKRFKVNVTAAE 175 Query: 62 QCDVADQQQL 71 D A + + Sbjct: 176 TADDASRAEA 185 >4J2O-A nrPDB Length = 363 Score = 39.5 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 27/173 (15%), Positives = 61/173 (35%), Gaps = 28/173 (16%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 KV L+TG G A + L K + + + + + + +++ K F Sbjct: 21 FKDKVLLITGGTGSFGNAVLKRFLETDIKEIRIFSRDEKK----QDDMRKKYHSAKLKFY 76 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN----EKNWEKTLQINLVSVISGTYL 117 DV D + + R +D + + A + E + + ++ N++ + Sbjct: 77 IGDVRDYNSILNATR-------GVDYIYHAAALKQVPSCEFHPMEAVKTNVLGTENVLEA 129 Query: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGI--VGFTRSAALA 168 + K+ ++ +S+ + P+ SK + V +S L Sbjct: 130 AIQNHVKR-------VVCLSTDKAVYPI---NAMGISKAMMEKVMVAKSRNLE 172 >6G2J-P nrPDB Length = 377 Score = 39.5 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 20/110 (18%), Positives = 42/110 (38%), Gaps = 14/110 (12%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 V+G VA V GA +GR L G++V + + + + + F+ Sbjct: 50 SVSGVVATVFGATGFLGRYVVNHLGRMGSQVIIPYRCDVYDIMHLRLMGDL---GQLTFL 106 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAG---VNNEKNWEKTLQINL 108 + D D+ +R + ++++N G ++E +N+ Sbjct: 107 EWDARDKDSIRKAVQHS-------NVVINLIGREWETRNFDFEDVF-VNI 148 >2C20-A nrPDB Length = 330 Score = 39.1 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 31/111 (27%), Positives = 46/111 (41%), Gaps = 17/111 (15%) Query: 8 ALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVAD 67 L+ G A IG + L+ +G V +VD NL+ G + + F D+ D Sbjct: 4 ILICGGAGYIGSHAVKKLVDEGLSVVVVD-NLQTGHEDAIT-------EGAKFYNGDLRD 55 Query: 68 QQQLRDTFR----KVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISG 114 + LRD F + V HF D LV GV+ EK + N+ + Sbjct: 56 KAFLRDVFTQENIEAVMHFAA-DSLV---GVSMEKPLQ-YYNNNVYGALCL 101 >1BXK-A nrPDB Length = 355 Score = 38.7 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 35/198 (17%), Positives = 69/198 (34%), Gaps = 35/198 (17%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64 + L+TG A IG A ++ + + V +VD AG +L + ++ F + D Sbjct: 2 RKILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGN--LMSLAPVAQSERFAFEKVD 59 Query: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQ-------INLVSVISGTYL 117 + D+ +L F + + D +++ + E + ++++ N+V + Sbjct: 60 ICDRAELARVFTEH-----QPDCVMH---LAAESHVDRSIDGPAAFIETNIVGTYTLLEA 111 Query: 118 GLDYM-----SKQNGGEGGIIIN------MSSL----AGLMPVAQQPVYCASKHGIVGFT 162 Y K++ I + S P A Y ASK Sbjct: 112 ARAYWNALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPYSASKASSDHLV 171 Query: 163 RSAALAANLMNSGVRLNA 180 R+ L + + N Sbjct: 172 RAWLRTYGL-PTLIT-NC 187 >4EUF-A nrPDB Length = 418 Score = 38.4 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 18/108 (16%), Positives = 35/108 (32%), Gaps = 12/108 (11%) Query: 6 KVALVTGAAQGIGRA--FAEALLLKGAKVALVDWNLEAGVQCKAALD----------EQF 53 K L+ GA+ G G A + A A V + A + + Sbjct: 61 KKVLIVGASSGFGLATRISVAFGGPEAHTIGVSYETGATDRRIGTAGWYNNIFFKEFAKK 120 Query: 54 EPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWE 101 + D + + + D FG++D+ V + K+++ Sbjct: 121 KGLVAKNFIEDAFSNETKDKVIKYIKDEFGKIDLFVYSLAAPRRKDYK 168 >1RPN-A nrPDB Length = 335 Score = 38.4 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 29/73 (39%), Gaps = 2/73 (2%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 + ALVTG G A+ LL KG +V + + + + L E + D+ Sbjct: 15 RSALVTGITGQDGAYLAKLLLEKGYRVHGLVARRSSDTRWR--LRELGIEGDIQYEDGDM 72 Query: 66 ADQQQLRDTFRKV 78 AD ++ K Sbjct: 73 ADACSVQRAVIKA 85 >3OND-A nrPDB Length = 488 Score = 38.4 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 28/109 (25%), Positives = 46/109 (42%), Gaps = 22/109 (20%) Query: 5 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64 GKVA+V G +G+ A AL GA+V + + + AL E + L ++ D Sbjct: 265 GKVAVVAGYGD-VGKGCAAALKQAGARVIVTEIDP------ICALQATMEGLQVLTLE-D 316 Query: 65 VADQQQLRDTFRKVVDHFGRLDILV--------NNAGVNNEKNWEKTLQ 105 V + + V G DI++ NNA V N +++ + Sbjct: 317 VVSEADI------FVTTTGNKDIIMLDHMKKMKNNAIVCNIGHFDNEID 359 >4K28-A nrPDB Length = 269 Score = 38.4 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 19/71 (26%), Positives = 25/71 (35%), Gaps = 2/71 (2%) Query: 5 GKVALVTGAAQGIGRAFAEALLLKG-AKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63 GK ALV G G+G A A AL G A + L D + L F Sbjct: 125 GKRALVIGCG-GVGSAIAYALAEAGIASITLCDPSTARMGAVCELLGNGFPGLTVSTQFS 183 Query: 64 DVADQQQLRDT 74 + D + + Sbjct: 184 GLEDFDLVANA 194 >4A10-A nrPDB Length = 447 Score = 38.4 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 25/141 (17%), Positives = 50/141 (35%), Gaps = 19/141 (13%) Query: 4 NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKT-LFIQ 62 G + L+ GA+ G+G ++A + G + + + AL + L I Sbjct: 220 QGDIVLIWGASGGLG-SYAIQFVKNGGGIPVAVVSSAQKEAAVRALGCDLVINRAELGIT 278 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYM 122 D+AD + +L +V AG + +E T ++ + + Sbjct: 279 DDIADDP---RRVVETGRKLAKL--VVEKAGREPDIVFEHTGRV----TFGLSVIVAR-- 327 Query: 123 SKQNGGEGGIIINMSSLAGLM 143 GG ++ S +G + Sbjct: 328 ------RGGTVVTCGSSSGYL 342 >1OC2-A nrPDB Length = 348 Score = 38.0 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 23/120 (19%), Positives = 40/120 (33%), Gaps = 12/120 (10%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 K +VTG A IG F + V + + KA L E + + D+ Sbjct: 5 KNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNKANL-EAILGDRVELVVGDI 63 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAG-VNNEKNWEKT---LQINLVSVISGTYLGLDY 121 AD + + K D +V+ A +N+ + + N + + Y Sbjct: 64 ADAELVDKLAAKA-------DAIVHYAAESHNDNSLNDPSPFIHTNFIGTYTLLEAARKY 116 >5GUP-L nrPDB Length = 377 Score = 37.6 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 30/157 (19%), Positives = 58/157 (36%), Gaps = 23/157 (14%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 V+G VA V GA +GR L G++V + + + + +F+ Sbjct: 50 SVSGIVATVFGATGFLGRYVVNHLGRMGSQVIVPYRCEPYDTMHLRPMGDL---GQIIFM 106 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDY 121 + + D+ +R ++++N G + WE T + V + + + Sbjct: 107 EWNGKDKDSIRKVVEHS-------NVVINLVG----REWE-TKNFDFEDVF----VKIPH 150 Query: 122 MSKQNGGEGGI--IINMSSLAGLMPVAQQPVYCASKH 156 Q E G+ +I++S L + Y SK Sbjct: 151 AIAQVSKEAGVEKLIHISHLNADIKSP--SRYLRSKA 185 >1KEU-A nrPDB Length = 361 Score = 37.6 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 29/195 (14%), Positives = 55/195 (28%), Gaps = 39/195 (20%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVA 66 L+TG A IG A ++ + + + +L + E + F D+ Sbjct: 2 KILITGGAGFIGSAVVRHIIKNTQDTVV-NIDKLTYAGNLESLSDISESNRYNFEHADIC 60 Query: 67 DQQQLRDTFRK----VVDHFG---RLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGL 119 D ++ F + V H +D + + ++ N+V + + Sbjct: 61 DSAEITRIFEQYQPDAVMHLAAESHVDR-----SITGPAAF---IETNIVGTYALLEVAR 112 Query: 120 DYMSKQNGGEGGII----INMSSLAGLMPVAQ-------------------QPVYCASKH 156 Y S + I+ + G +P Y ASK Sbjct: 113 KYWSALGEDKKNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTAYAPSSPYSASKA 172 Query: 157 GIVGFTRSAALAANL 171 R+ L Sbjct: 173 SSDHLVRAWRRTYGL 187 >5INT-A nrPDB Length = 220 Score = 37.6 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 22/110 (20%), Positives = 38/110 (34%), Gaps = 32/110 (29%) Query: 3 VNGKVALVTGA---------------AQG-IGRAFAEALLLKGAKVALVDWNLEAGVQCK 46 + GK L+T + G +G A AE + GA+V LV Sbjct: 4 LQGKRILITAGPTREKIDPVRFMTNFSSGKMGYAIAEVAVNLGAEVILVSGPTALN---- 59 Query: 47 AALDEQFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN 96 P +Q + +D V+ H+ +D+++ A V + Sbjct: 60 -------PPLHVTTVQV-----ESAQDMLEAVIQHYQNVDVVIKTAAVAD 97 >1VL0-A nrPDB Length = 292 Score = 37.2 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 25/174 (14%), Positives = 51/174 (29%), Gaps = 51/174 (29%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVA 66 L+TGA +GR + L K +V D D+ Sbjct: 14 KILITGANGQLGREIQKQLKGKNVEVIPTDVQD-----------------------LDIT 50 Query: 67 DQQQLRDTFRKVVDHFGRLDILVNNAGVNN----EKNWEKTLQINLVSVISGTYLGLDYM 122 + + F + + ++++N A E+ ++ +IN + + Sbjct: 51 NVLAVNKFFNE-----KKPNVVINCAAHTAVDKCEEQYDLAYKINAIGPKNLAAAA---- 101 Query: 123 SKQNGGEGGIIINMSSLAGLMPVAQ-----------QPVYCASKHGIVGFTRSA 165 G I+ +S+ A+ Q Y +K F ++ Sbjct: 102 ----YSVGAEIVQISTDYVFDGEAKEPITEFDEVNPQSAYGKTKLEGENFVKAL 151 >3HFS-A nrPDB Length = 338 Score = 37.2 bits (85), Expect = 0.008, Method: Composition-based stats. Identities = 22/141 (15%), Positives = 41/141 (29%), Gaps = 17/141 (12%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 K A V G + + LL KG V + + + + L E E + D+ Sbjct: 10 KTACVVGGTGFVASLLVKLLLQKGYAVNTTVRDPD-NQKKVSHLLELQELGDLKIFRADL 68 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAG---VNNEKNWEKTLQINLVSVISGTYLGLDYM 122 D+ D + + A +E ++ + V++ Sbjct: 69 TDELSFEAPIA-------GCDFVFHVATPVHFASEDPENDMIKPAIQGVVNVMKACTRA- 120 Query: 123 SKQNGGEGGIIINMSSLAGLM 143 +I SS A + Sbjct: 121 -----KSVKRVILTSSAAAVT 136 >2X86-A nrPDB Length = 357 Score = 36.8 bits (84), Expect = 0.009, Method: Composition-based stats. Identities = 23/106 (21%), Positives = 44/106 (41%), Gaps = 16/106 (15%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 ++ +VTG A IG +AL KG LV NL+ G + +D ++ Sbjct: 47 RMIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVD------------LNI 94 Query: 66 ADQQQLRDTFRKVV--DHFGRLDILVNNAGVNNEKNWEK--TLQIN 107 AD D +++ + FG ++ + + ++ W+ + N Sbjct: 95 ADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNN 140 >4XRR-A nrPDB Length = 456 Score = 36.8 bits (84), Expect = 0.011, Method: Composition-based stats. Identities = 20/98 (20%), Positives = 30/98 (30%), Gaps = 5/98 (5%) Query: 9 LVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQ 68 +V A +G A L +GA+V VD + +A EP V D Sbjct: 18 VVIAGAGYVGTCLAVTLAGRGAEVVAVDSDPGTVADLRAGRCRLPEPGLAGA----VRDL 73 Query: 69 QQLRDTFRKV-VDHFGRLDILVNNAGVNNEKNWEKTLQ 105 D G D+++ G + E Sbjct: 74 AATGRLTASTSYDPVGAADVVIVTVGTPTDAGHEMVTD 111 >6DEB-A nrPDB Length = 285 Score = 36.8 bits (84), Expect = 0.011, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 22/41 (53%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEA 41 + + GK A++ GA+ +GR A LL GA V++ + Sbjct: 156 IDLEGKDAVIIGASNIVGRPMATMLLNAGATVSVCHIKTKD 196 >3DFZ-A nrPDB Length = 223 Score = 36.4 bits (83), Expect = 0.012, Method: Composition-based stats. Identities = 22/110 (20%), Positives = 42/110 (38%), Gaps = 15/110 (13%) Query: 1 MHVNGKVALVTG----AAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQ 56 + + G+ LV G A + I + L +GA + +V + A + A + + Sbjct: 27 LDLKGRSVLVVGGGTIATRRI-----KGFLQEGAAITVVAPTVSAEINEWEAKGQLRVKR 81 Query: 57 KTLFIQCDVAD-----QQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWE 101 K + + D+ + K V + D LVN A ++ N + Sbjct: 82 KKVGEE-DLLNVFFIVVATNDQAVNKFVKQHIKNDQLVNMASSFSDGNIQ 130 >5F5N-A nrPDB Length = 289 Score = 36.4 bits (83), Expect = 0.012, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 25/77 (32%), Gaps = 6/77 (7%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 + LVTGA G A ALL +G V + + + D+ Sbjct: 2 RTILVTGATGTQGGATVRALLARGRPVRALVRDPGTDAARA------LAAAGVSLVTGDL 55 Query: 66 ADQQQLRDTFRKVVDHF 82 DQ LR V F Sbjct: 56 NDQASLRAAMADVHGVF 72 >3SXP-A nrPDB Length = 362 Score = 36.4 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 29/161 (18%), Positives = 48/161 (29%), Gaps = 28/161 (17%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKG--AKVALVDWNLEAGVQCKAALDEQFE-----P 55 + + L+TG A +G A AKV ++D + Sbjct: 8 LENQTILITGGAGFVGSNLAFHFQENHPKAKVVVLDKFRSNTLFSNNRPSSLGHFKNLIG 67 Query: 56 QKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGT 115 K I D+ + LR + D L + A V+ T +N V+ Sbjct: 68 FKGEVIAADINNPLDLRRLEKL------HFDYLFHQAAVS------DTTMLNQELVMKTN 115 Query: 116 YLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKH 156 Y + + + +I SS VY +K Sbjct: 116 YQAFLNLLEIARSKKAKVIYASSAG---------VYGNTKA 147 >1EQ2-A nrPDB Length = 310 Score = 36.0 bits (82), Expect = 0.015, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 42/104 (40%), Gaps = 16/104 (15%) Query: 8 ALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVAD 67 +VTG A IG +AL KG LV NL+ G + +D ++AD Sbjct: 2 IIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVD------------LNIAD 49 Query: 68 QQQLRDTFRKVV--DHFGRLDILVNNAGVNNEKNWEK--TLQIN 107 D +++ + FG ++ + + ++ W+ + N Sbjct: 50 YMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNN 93 >2EXX-A nrPDB Length = 306 Score = 36.0 bits (82), Expect = 0.016, Method: Composition-based stats. Identities = 19/83 (22%), Positives = 30/83 (36%), Gaps = 7/83 (8%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKG-AKVALVDWNLEAGVQCKAALDEQFEPQKTL 59 + V+ K+ +V G G + A LL G KV +V N + ++ Q Sbjct: 7 LMVDKKLVVVFGGTGAQGGSVARTLLEDGTFKVRVVTRNP------RKKAAKELRLQGAE 60 Query: 60 FIQCDVADQQQLRDTFRKVVDHF 82 +Q D DQ + F Sbjct: 61 VVQGDQDDQVIMELALNGAYATF 83 >3VPX-A nrPDB Length = 364 Score = 36.0 bits (82), Expect = 0.017, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 26/65 (40%), Gaps = 2/65 (3%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 + GK V G + A E L +GAK+ + D N EA + A ++ Sbjct: 170 SLAGKTVAVQGVGN-VAYALCEYLHEEGAKLIITDINEEAVQRAVDAFGATAVGINEIYS 228 Query: 62 Q-CDV 65 Q D+ Sbjct: 229 QEADI 233 >2GGS-A nrPDB Length = 273 Score = 36.0 bits (82), Expect = 0.018, Method: Composition-based stats. Identities = 25/114 (21%), Positives = 42/114 (36%), Gaps = 26/114 (22%) Query: 9 LVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQ 68 L+TGA+ +G + L + +V V + E + D+ D Sbjct: 4 LITGASGQLGIELSRLLSER-HEVIKVYNSSEIQG----------------GYKLDLTDF 46 Query: 69 QQLRDTFRKVVDHFGRLDILVNNAGVNN----EKNWEKTLQINLVSVISGTYLG 118 +L D K R D+++N A + + E EK +IN +V G Sbjct: 47 PRLEDFIIK-----KRPDVIINAAAMTDVDKCEIEKEKAYKINAEAVRHIVRAG 95 >1WVG-A nrPDB Length = 359 Score = 35.7 bits (81), Expect = 0.020, Method: Composition-based stats. Identities = 27/169 (15%), Positives = 53/169 (31%), Gaps = 30/169 (17%) Query: 4 NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63 GK VTG G + L GA V + + + + Sbjct: 8 QGKRVFVTGHTGFKGSWLSLWLTEMGAIVKGYALDAPTVPSLFEIVRLNDLMESHIG--- 64 Query: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVN----NEKNWEKTLQINLVSVISGTYLGL 119 D+ D ++LR + + + +I+ + A + + KT N++ + Sbjct: 65 DIRDFEKLRSSIAEF-----KPEIVFHMAAQPLVRLSYEQPIKTYSTNVMGTVHLLETV- 118 Query: 120 DYMSKQNGGEGGIIINMSS---------LAGLM---PVAQQPVYCASKH 156 + G ++N++S + G P+ Y SK Sbjct: 119 -----KQVGNIKAVVNITSDKCYDNREWVWGYRENEPMGGYDPYSNSKG 162 >4KTT-E nrPDB Length = 327 Score = 35.7 bits (81), Expect = 0.022, Method: Composition-based stats. Identities = 21/137 (15%), Positives = 39/137 (28%), Gaps = 33/137 (24%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 + LVTGA +GRA + + + F Q ++ Sbjct: 22 RRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRA----------------RPKFEQVNL 65 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNN----EKNWEKTLQINLVSVISGTYLGLDY 121 D + H ++V+ A E + Q+N+ + + Sbjct: 66 LDSNAVHHIIHDFQPH-----VIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAV 120 Query: 122 MSKQNGGEGGIIINMSS 138 G +I +SS Sbjct: 121 --------GAFLIYISS 129 >1O89-A nrPDB Length = 345 Score = 35.7 bits (81), Expect = 0.022, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 27/74 (36%), Gaps = 1/74 (1%) Query: 8 ALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVAD 67 +VTGA+ G+G L G +V V E+ + +L + F + + Sbjct: 171 IVVTGASGGVGSTAVALLHKLGYQVVAVS-GRESTHEYLKSLGASRVLPRDEFAESRPLE 229 Query: 68 QQQLRDTFRKVVDH 81 +Q V D Sbjct: 230 KQVWAGAIDTVGDK 243 >3LK7-A nrPDB Length = 451 Score = 35.7 bits (81), Expect = 0.025, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 23/69 (33%), Gaps = 1/69 (1%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 K LV G A+ G A A L GA V + D +L E+ Sbjct: 7 FENKKVLVLGLARS-GEAAARLLAKLGAIVTVNDGKPFDENPTAQSLLEEGIKVVCGSHP 65 Query: 63 CDVADQQQL 71 ++ D+ Sbjct: 66 LELLDEDFC 74 >4J6F-A nrPDB Length = 382 Score = 35.3 bits (80), Expect = 0.027, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 28/70 (40%), Gaps = 7/70 (10%) Query: 5 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64 G+ LVTGA+ G+G A L V + AG +AA+ + Q D Sbjct: 207 GETVLVTGASGGVGSAI-IQLARARGAVPIA----VAGPGKEAAMLDIGAQAVVTRGQGD 261 Query: 65 VADQQQLRDT 74 +A + + Sbjct: 262 LA--EAVEAA 269 >7REQ-A nrPDB Length = 727 Score = 35.3 bits (80), Expect = 0.028, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 31/87 (35%), Gaps = 11/87 (12%) Query: 21 FAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQ----QLRDTFR 76 A A G V + G + + + + V+ L R Sbjct: 616 IATAYADLGFDV-------DVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPALR 668 Query: 77 KVVDHFGRLDILVNNAGVNNEKNWEKT 103 K +D GR DIL+ GV E+++++ Sbjct: 669 KELDKLGRPDILITVGGVIPEQDFDEL 695 >1VPD-A nrPDB Length = 299 Score = 35.3 bits (80), Expect = 0.028, Method: Composition-based stats. Identities = 18/51 (35%), Positives = 24/51 (47%), Gaps = 1/51 (1%) Query: 16 GI-GRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 GI G+ ++ LL G + + D N EA AA E K + QCDV Sbjct: 14 GIMGKPMSKNLLKAGYSLVVSDRNPEAIADVIAAGAETASTAKAIAEQCDV 64 >3NJ4-A nrPDB Length = 435 Score = 35.3 bits (80), Expect = 0.031, Method: Composition-based stats. Identities = 28/139 (20%), Positives = 51/139 (36%), Gaps = 17/139 (12%) Query: 5 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCK------AALDEQFEPQKT 58 GKVA+V G +G+ A+AL GA+V + + + +Q +DE + Sbjct: 216 GKVAVVAGYGD-VGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNI 274 Query: 59 LFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLG 118 V + + + D +V N G + + K L N V ++ Sbjct: 275 F-----VTTTGCIDIILGRHFEQMKD-DAIVCNIGHFDVEIDVKWLNENAVEKVNI---- 324 Query: 119 LDYMSKQNGGEGGIIINMS 137 + + G II ++ Sbjct: 325 KPQVDRYRLKNGRRIILLA 343 >1XDW-A nrPDB Length = 331 Score = 34.9 bits (79), Expect = 0.039, Method: Composition-based stats. Identities = 22/86 (25%), Positives = 31/86 (36%), Gaps = 5/86 (5%) Query: 10 VTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQ---CKAALDEQFEPQKTLFIQCDVA 66 V G + IGR A+ GA V D G++ + +LDE E + I Sbjct: 151 VVGLGR-IGRVAAQIFHGMGATVIGEDVFEIKGIEDYCTQVSLDEVLEKSDIITIHAPYI 209 Query: 67 DQQQLRDTFRKVVDHFGRLDILVNNA 92 + T + ILVN A Sbjct: 210 KENGAVVTRDFLKKMKDGA-ILVNCA 234 >3WMX-A nrPDB Length = 358 Score = 34.5 bits (78), Expect = 0.044, Method: Composition-based stats. Identities = 38/204 (18%), Positives = 66/204 (32%), Gaps = 46/204 (22%) Query: 5 GK-VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63 GK L+ GA IG A AL E + + + + + Sbjct: 24 GKPKILIVGANGQIGSELALALA-------------ERYGRTNVITSDVVPTGRHVHLTH 70 Query: 64 DVADQQQLRDTFRKVVDHFG--RLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLD- 120 ++ + + VV+ G ++ +L EK + +N+ S+++ L Sbjct: 71 EMLNATDRGEL-ATVVERHGITQVYLLAAALSATGEKAPQWAWNLNMTSLLNVLELARQT 129 Query: 121 YMSKQNGGEGGIIINMSSLAGLMP--VAQQ----------PVYCASKHGIVGFTRSAALA 168 + + SS+A P A Q VY SK G+ R Sbjct: 130 GLERVFWP--------SSIAAFGPTTPAGQTPQKTVMEPTTVYGISKQAGEGWCR----- 176 Query: 169 ANLMNSGVRLNAIC-PGFV--NTA 189 N GV + ++ PG + T Sbjct: 177 WYHANHGVDVRSVRYPGLISHKTP 200 >5ENV-A nrPDB Length = 347 Score = 34.1 bits (77), Expect = 0.056, Method: Composition-based stats. Identities = 27/145 (18%), Positives = 51/145 (35%), Gaps = 16/145 (11%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLK-GAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 + G ++GAA G+G + A G +V +D G + K L + + Sbjct: 168 MAGHWVAISGAAGGLG-SLAVQYAKAMGYRVLGID-----GGEGKEELFRSIGGE----V 217 Query: 62 QCDVADQQQLRDTFRKVVD--HFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGL 119 D ++ + K D G +++ V+ A + + ++ N +V+ G G Sbjct: 218 FIDFTKEKDIVGAVLKATDGGAHGVINVSVSEAAIEAST---RYVRANGTTVLVGMPAGA 274 Query: 120 DYMSKQNGGEGGIIINMSSLAGLMP 144 S I + S G Sbjct: 275 KCCSDVFNQVVKSISIVGSYVGNRA 299 >1DB3-A nrPDB Length = 372 Score = 34.1 bits (77), Expect = 0.061, Method: Composition-based stats. Identities = 21/76 (27%), Positives = 29/76 (38%), Gaps = 3/76 (3%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQ---KTLFIQ 62 KVAL+TG G AE LL KG +V + + + Q K Sbjct: 2 KVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPHTCNPKFHLHY 61 Query: 63 CDVADQQQLRDTFRKV 78 D++D L R+V Sbjct: 62 GDLSDTSNLTRILREV 77 >1C0L-A nrPDB Length = 363 Score = 34.1 bits (77), Expect = 0.063, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 24/63 (38%), Gaps = 2/63 (3%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 MH +V ++ + IG + A L KG V ++ +L V + T F Sbjct: 3 MHSQKRVVVL--GSGVIGLSSALILARKGYSVHILARDLPEDVSSQTFASPWAGANWTPF 60 Query: 61 IQC 63 + Sbjct: 61 MTL 63 >3PVZ-A nrPDB Length = 399 Score = 34.1 bits (77), Expect = 0.067, Method: Composition-based stats. Identities = 23/126 (18%), Positives = 48/126 (38%), Gaps = 14/126 (11%) Query: 9 LVTGAAQGIGRAFAEA-LLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF--IQCDV 65 LV G A IG+A + K+ +VD + V+ + F F D+ Sbjct: 39 LVLGGAGSIGQAVTKEIFKRNPQKLHVVDISENNMVELVRDIRSSFGYINGDFQTFALDI 98 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAG---VNNEKN---WEKTLQINLVSVISGTYLGL 119 + + + G+ D ++N + V +EK+ + + +N+ + + Sbjct: 99 GSIE-----YDAFIKADGQYDYVLNLSALKHVRSEKDPFTLMRMIDVNVFNTDKTIQQSI 153 Query: 120 DYMSKQ 125 D +K+ Sbjct: 154 DAGAKK 159 >4WOK-A nrPDB Length = 336 Score = 33.7 bits (76), Expect = 0.074, Method: Composition-based stats. Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 9/70 (12%) Query: 8 ALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVAD 67 LV G A IG A+ L +G + D NL G Q + F++ D+ D Sbjct: 14 VLVVGGAGFIGSHTAKLLAGQGYAPVVYD-NLSTGHQSAV--------RWGDFVEGDILD 64 Query: 68 QQQLRDTFRK 77 Q +L +T K Sbjct: 65 QARLVETMEK 74 >6ACQ-A nrPDB Length = 302 Score = 33.7 bits (76), Expect = 0.080, Method: Composition-based stats. Identities = 12/35 (34%), Positives = 17/35 (48%), Gaps = 2/35 (5%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLE 40 KV ++ A +G A+A KG +V L D E Sbjct: 23 KVCVI--GAGTMGSGIAQAFAAKGFEVVLRDIKDE 55 >3HZZ-A nrPDB Length = 467 Score = 33.7 bits (76), Expect = 0.080, Method: Composition-based stats. Identities = 25/145 (17%), Positives = 51/145 (35%), Gaps = 27/145 (18%) Query: 4 NGKVALVTGAAQGIGRAFAEALLLK-GAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 G L+ GA+ G+G ++A L GA V + + C++ E + + Sbjct: 246 QGDNVLIWGASGGLG-SYATQFALAGGANPICVVSSPQKAEICRSMGAEAIIDRNAEGYK 304 Query: 63 C----DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLG 118 D ++ + +++ + G DI + +E + + + T Sbjct: 305 FWKDEHTQDPKEWKRFGKRIRELTGGEDI---------DIVFEHPGRETFGASVYVTR-- 353 Query: 119 LDYMSKQNGGEGGIIINMSSLAGLM 143 +GG I +S +G M Sbjct: 354 ----------KGGTITTCASTSGYM 368 >4DGK-A nrPDB Length = 501 Score = 33.3 bits (75), Expect = 0.10, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 25/73 (34%), Gaps = 4/73 (5%) Query: 10 VTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQ 69 V GA G G A A L G V L++ + G + D+ F + + D Sbjct: 6 VIGAGFG-GLALAIRLQAAGIPVLLLEQRDKPGGRAYVYEDQGFTFDAGPTV---ITDPS 61 Query: 70 QLRDTFRKVVDHF 82 + + F Sbjct: 62 AIEELFALAGKQL 74 >3K4W-A nrPDB Length = 291 Score = 33.3 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 31/80 (38%), Gaps = 13/80 (16%) Query: 122 MSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKH---------GIVGFTRSAALAA--N 170 M+ +G + SS+ G + A +K I TR A+A Sbjct: 56 MAAAGIEQGVCVGRNSSVLGSVSNADVA--AVAKAYPDKFHPVGSIEAATRKEAMAQMQE 113 Query: 171 LMNSGVRLNAICPGFVNTAI 190 +++ G+R+ + PG T + Sbjct: 114 ILDLGIRIVNLEPGVWATPM 133 >3PEF-A nrPDB Length = 287 Score = 33.3 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 21/52 (40%), Gaps = 1/52 (1%) Query: 16 GI-GRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVA 66 GI G A A+ L+ G V + + + E + A E+ + C V Sbjct: 10 GIMGSAMAKNLVKAGCSVTIWNRSPEKAEELAALGAERAATPCEVVESCPVT 61 >4UUP-A nrPDB Length = 341 Score = 33.0 bits (74), Expect = 0.13, Method: Composition-based stats. Identities = 24/108 (22%), Positives = 38/108 (35%), Gaps = 18/108 (16%) Query: 8 ALVTGAAQGIGRAFAEALLLKGA-----KVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 L+TGAA IG A A + G KV L + ++ + + + + Sbjct: 7 VLITGAAGQIGYALAFRIAK-GDLFGDRKVVLHLLEIPPAMKALEGVCMELQDCAFPTLA 65 Query: 63 CDVADQQQLRDTFRKVVDHF-----------GRLDILVNNAGVNNEKN 99 VA + F+ V F R D+L NAG+ + Sbjct: 66 GVVA-TDDPEEAFKDVDVAFLVGSFPRKPGMERADLLEKNAGIFKVQG 112 >4KDR-A nrPDB Length = 223 Score = 33.0 bits (74), Expect = 0.13, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 30/86 (34%), Gaps = 14/86 (16%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 + GK L G GI AE++ +GA V +D E A L + ++Q Sbjct: 61 LFGKKVLDVGCGGGI---LAESMAREGATVTGLDMGFE--PLQVAKLHALESGIQVDYVQ 115 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDIL 88 H G+ D++ Sbjct: 116 ---------ETVEEHAAKHAGQYDVV 132 >4KDC-A nrPDB Length = 246 Score = 33.0 bits (74), Expect = 0.14, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 30/86 (34%), Gaps = 14/86 (16%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 + GK L G GI AE++ +GA V +D E A L + ++Q Sbjct: 61 LFGKKVLDVGCGGGI---LAESMAREGATVTGLDMGFE--PLQVAKLHALESGIQVDYVQ 115 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDIL 88 H G+ D++ Sbjct: 116 ---------ETVEEHAAKHAGQYDVV 132 >3DMF-A nrPDB Length = 381 Score = 33.0 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 20/89 (22%), Positives = 33/89 (37%), Gaps = 15/89 (16%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 V G+ L GA G A L GA+V V+ +L + + + ++ Sbjct: 232 VRGRQVLDLGAGYG---ALTLPLARMGAEVVGVEDDLASVLSLQK------------GLE 276 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNN 91 + Q L + + R DI+V N Sbjct: 277 ANALKAQALHSDVDEALTEEARFDIIVTN 305 >4KUG-A nrPDB Length = 290 Score = 33.0 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 15/35 (42%), Gaps = 1/35 (2%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLE 40 K V GA +G +A KG +V + D E Sbjct: 2 KKVFVLGAGT-MGAGIVQAFAAKGCEVIVRDIKEE 35 >2Q4B-A nrPDB Length = 253 Score = 33.0 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 33/83 (39%), Gaps = 14/83 (16%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVA 66 LVTGA+ G+ L +G+ D + G+ A E+ + +FI D+ Sbjct: 6 TVLVTGASGRTGQ-IVYKKLKEGS-----DKFVAKGLVRSAQGKEKIGGEADVFI-GDIT 58 Query: 67 DQQQLRDTFRKVVDHFGRLDILV 89 D + F+ +D LV Sbjct: 59 DADSINPAFQ-------GIDALV 74 >3CT4-A nrPDB Length = 332 Score = 32.6 bits (73), Expect = 0.16, Method: Composition-based stats. Identities = 49/277 (17%), Positives = 89/277 (32%), Gaps = 57/277 (20%) Query: 4 NGKVALVTGAAQGIGRAFAEALLLKG---AKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 +GKVALV+G G A A + +G A V + Q A+ E L Sbjct: 45 SGKVALVSGGGSGHEPAHA-GFVGEGMLSAAVCGAIFTSPTPDQIYEAIKSADEGAGVLL 103 Query: 61 IQ----CDVADQQQLRDTFRKVVDHFGRL----DILVNN--------------------- 91 I DV + + R+ ++ DI V N Sbjct: 104 IIKNYLGDVMNFEMAREMAEMEEIKVEQIIVDDDIAVENSLYTQGRRGVAGTVLVHKILG 163 Query: 92 AGVNNEKNWEKTLQINLVSV--ISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQP 149 A + E + ++ + V I L L + G+ G +++ + + + + +P Sbjct: 164 AAAHQEASLDEIKDLADKVVKNIKTIGLALSAATVPEVGKPGFVLDDNEIEYGVGIHSEP 223 Query: 150 VYCASKHGIVGFTRSAALAANL-------------MNSGVRLNAICPGFVNTAILESIEK 196 Y K S LA L G+ +N G T ++E Sbjct: 224 GYRREK-----MKTSYELATELVGKLKEEFKFEAGQKYGILVN----GMGATPLMEQFIF 274 Query: 197 EENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLI 233 ++ + + ++ K + +A +T+I Sbjct: 275 MNDVAKLLTEENIEILFKKVGNYMTSIDMAGLSLTMI 311 >1MLD-A nrPDB Length = 314 Score = 32.6 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 31/171 (18%), Positives = 51/171 (29%), Gaps = 17/171 (9%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 KVA V GA+ GIG+ + L L +++ A L Sbjct: 2 KVA-VLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRATVKGYLGP- 59 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNW--EKTLQINLVSVISGTYLGLDYMS 123 ++ D D++V AGV + + N V + T + Sbjct: 60 ----------EQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCP 109 Query: 124 KQNGGEGGIIINMSSLAGLMPVAQQPVYCASK-HGIVGF--TRSAALAANL 171 +N + + VY +K G+ R+ A A L Sbjct: 110 DAMICIISNPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANAFVAEL 160 >1V8B-A nrPDB Length = 479 Score = 32.6 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 20/113 (17%), Positives = 46/113 (40%), Gaps = 22/113 (19%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 ++GK+ ++ G +G+ A ++ GA+V + + + +Q Sbjct: 255 ISGKIVVICGYGD-VGKGCASSMKGLGARVYITEIDPICAIQAVME-------------G 300 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDI--------LVNNAGVNNEKNWEKTLQIN 107 +V ++ D + G +D+ + NNA V N +++ +Q+N Sbjct: 301 FNVVTLDEIVDKGDFFITCTGNVDVIKLEHLLKMKNNAVVGNIGHFDDEIQVN 353 >5UOG-A nrPDB Length = 344 Score = 32.6 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 16/91 (17%), Positives = 29/91 (31%), Gaps = 2/91 (2%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + + G+ + G + IG A A L G +A G+ + Sbjct: 160 LSLRGRTVGLFGLGR-IGLAIARRLEAFGVSIAYHTRTPREGLGFTYHPTLVGMAEAVDT 218 Query: 61 IQCDV-ADQQQLRDTFRKVVDHFGRLDILVN 90 + V L+ V+ G +L+N Sbjct: 219 LIVIVPGTASTLKAVNADVLSALGPKGVLIN 249 >4WLE-A nrPDB Length = 340 Score = 32.6 bits (73), Expect = 0.21, Method: Composition-based stats. Identities = 36/185 (19%), Positives = 59/185 (31%), Gaps = 22/185 (11%) Query: 4 NGKVALVTGAAQGIGRAFAEALLLKG--AKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 N KVA V GA+ GIG+ + L +++ L D GV + E K Sbjct: 26 NAKVA-VLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETKAAVKGYLG 84 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNW--EKTLQINLVSVISGTYLGL 119 ++ D D++V AGV + + N V + T Sbjct: 85 P-------------EQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACA 131 Query: 120 DYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASK-HGIVGF--TRSAALAANLMN-SG 175 + + +N + + VY +K G+ R+ A L Sbjct: 132 QHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDP 191 Query: 176 VRLNA 180 R+N Sbjct: 192 ARVNV 196 >1YHU-C nrPDB Length = 148 Score = 32.6 bits (73), Expect = 0.21, Method: Composition-based stats. Identities = 18/49 (36%), Positives = 23/49 (46%), Gaps = 1/49 (2%) Query: 42 GVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVN 90 G + AAL + K LF + +VAD VV G LDIL+N Sbjct: 33 GEEVFAALFKMVPAAKNLFTRVNVADINSPE-FQGHVVRVMGGLDILIN 80 >5UZH-A nrPDB Length = 345 Score = 32.2 bits (72), Expect = 0.22, Method: Composition-based stats. Identities = 21/76 (27%), Positives = 29/76 (38%), Gaps = 3/76 (3%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVA-LVDWNLEAGVQCKAALDEQFEPQKTLF--IQ 62 KVAL+TG G AE LL KG V ++ + L + K F + Sbjct: 2 KVALITGITGQDGSYLAEFLLEKGYMVYGIIRRSSSFNTGRVEHLYKDIHITKAKFKLLY 61 Query: 63 CDVADQQQLRDTFRKV 78 D+ D L K+ Sbjct: 62 GDLTDTGNLISIIAKI 77 >5LV5-A nrPDB Length = 403 Score = 32.2 bits (72), Expect = 0.23, Method: Composition-based stats. Identities = 13/80 (16%), Positives = 24/80 (30%), Gaps = 4/80 (5%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 + GK L GA GI + GA+ Q + + + + Sbjct: 109 LRGKTVLDVGAGTGI---LSIFCAQAGARRVYAVEASAIWQQAREVVRLNGLEDRVHVLP 165 Query: 63 CDVADQQQLRDTFRKVVDHF 82 V + L + +V + Sbjct: 166 GPVETVE-LPERVDAIVSEW 184 >5EGS-A nrPDB Length = 376 Score = 32.2 bits (72), Expect = 0.24, Method: Composition-based stats. Identities = 12/78 (15%), Positives = 22/78 (28%), Gaps = 6/78 (7%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 + GK L GA GI + GA+ Q + + + + Sbjct: 82 LRGKTVLDVGAGTGI---LSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLP 138 Query: 63 CDVAD---QQQLRDTFRK 77 V +Q+ + Sbjct: 139 GPVETVELPEQVDAIVSE 156 >5NUE-A nrPDB Length = 332 Score = 32.2 bits (72), Expect = 0.26, Method: Composition-based stats. Identities = 19/109 (17%), Positives = 36/109 (33%), Gaps = 15/109 (13%) Query: 7 VALVTGAAQGIGRAFAEALLL---KGAK--VALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 LVTGAA IG A + GA V L ++ + + + + Sbjct: 7 RVLVTGAAGQIGYALVPMIARGIMLGADQPVILHMLDIPPAAEALNGVKMELIDAAFPLL 66 Query: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEK--TLQINL 108 + VA + +++ V G ++ E+ + N+ Sbjct: 67 KGVVATTDAVEGCT--------GVNVAVMVGGFPRKEGMERKDVMSKNV 107 >1RKX-A nrPDB Length = 357 Score = 32.2 bits (72), Expect = 0.26, Method: Composition-based stats. Identities = 34/203 (16%), Positives = 60/203 (29%), Gaps = 34/203 (16%) Query: 4 NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63 GK VTG G + L GA V Q + Sbjct: 8 QGKRVFVTGHTGFKGGWLSLWLQTMGATVKGYSLTAPTVPSLFETARVADGMQSEIG--- 64 Query: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVN----NEKNWEKTLQINLVSVISGTYLGL 119 D+ DQ +L ++ R+ I+ + A + +T N++ + + Sbjct: 65 DIRDQNKLLESIREFQPE-----IVFHMAAQPLVRLSYSEPVETYSTNVMGTVYL-LEAI 118 Query: 120 DYMSKQNGGEGGIIINMSS---------LAGLM---PVAQQPVYCASKHGIVGFTRSAAL 167 ++ G ++N++S + G + Y SK T S Sbjct: 119 RHV-----GGVKAVVNITSDKCYDNKEWIWGYRENEAMGGYDPYSNSKGCAELVTSSYRN 173 Query: 168 A----ANLMNSGVRLNAICPGFV 186 + AN G + + G V Sbjct: 174 SFFNPANYGQHGTAVATVRAGNV 196 >6C55-A nrPDB Length = 340 Score = 31.8 bits (71), Expect = 0.29, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 23/63 (36%), Gaps = 2/63 (3%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 + GK V G G A A+ L G V + + + K + F + + Q Sbjct: 15 LQGKKIAVVGYGS-QGHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPVAEAV-KQ 72 Query: 63 CDV 65 DV Sbjct: 73 ADV 75 >3N58-A nrPDB Length = 464 Score = 31.8 bits (71), Expect = 0.29, Method: Composition-based stats. Identities = 13/44 (29%), Positives = 24/44 (54%), Gaps = 1/44 (2%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCK 46 + GKVA+V G +G+ A++L GA+V + + + +Q Sbjct: 245 MAGKVAVVCGYGD-VGKGSAQSLAGAGARVKVTEVDPICALQAA 287 >5JXW-A nrPDB Length = 498 Score = 31.8 bits (71), Expect = 0.30, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 38/94 (40%), Gaps = 11/94 (11%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWN-----LEAGVQCKAALDEQFEPQK 57 + GK +V G + +G+ A+ L GA+V + + + + + ++ E + Sbjct: 269 LAGKKIVVLGYGE-VGKGCAQGLSGVGARVIVTEIDPICALQASMEGYQVSVLEDVVSEA 327 Query: 58 TLFIQC----DVADQQQLRDTFRKV-VDHFGRLD 86 +FI DV + +R + + G D Sbjct: 328 DIFITATGNKDVITVEHMRKMKENAYIANIGHFD 361 >4B4V-A nrPDB Length = 303 Score = 31.8 bits (71), Expect = 0.32, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 25/65 (38%), Gaps = 1/65 (1%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEP-QKTL 59 + + GK A+V G + +G+ A LL A V + + + D K Sbjct: 175 IEIAGKHAVVVGRSAILGKPMAMMLLQANATVTICHSRTQNLPELVKQADIIVGAVGKAE 234 Query: 60 FIQCD 64 IQ D Sbjct: 235 LIQKD 239 >2EER-A nrPDB Length = 347 Score = 31.8 bits (71), Expect = 0.32, Method: Composition-based stats. Identities = 16/44 (36%), Positives = 20/44 (45%), Gaps = 1/44 (2%) Query: 6 KVALVTGAAQGIGR-AFAEALLLKGAKVALVDWNLEAGVQCKAA 48 K +V GA G+G A A + GA + VD EA K A Sbjct: 172 KTLVVIGAGGGLGTMAIQIAKAVSGATIIGVDVREEALEAAKRA 215 >5GXF-A nrPDB Length = 330 Score = 31.8 bits (71), Expect = 0.33, Method: Composition-based stats. Identities = 14/35 (40%), Positives = 16/35 (45%) Query: 8 ALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAG 42 LVTGAA G+G L G +VA V E Sbjct: 153 VLVTGAAGGVGSVATAILAHLGYEVAAVTGRPETA 187 >1JAY-A nrPDB Length = 212 Score = 31.8 bits (71), Expect = 0.34, Method: Composition-based stats. Identities = 8/33 (24%), Positives = 15/33 (45%), Gaps = 1/33 (3%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWN 38 +VAL+ G +G+ A L G ++ + Sbjct: 2 RVALL-GGTGNLGKGLALRLATLGHEIVVGSRR 33 >2DFV-A nrPDB Length = 347 Score = 31.8 bits (71), Expect = 0.36, Method: Composition-based stats. Identities = 14/80 (17%), Positives = 28/80 (35%), Gaps = 9/80 (11%) Query: 3 VNGKVALVTGAA--QGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFE----PQ 56 ++GK L+TGA +G A A+ GA +V + + + + + Sbjct: 165 ISGKSVLITGAGPLGLLGIAVAK---ASGAYPVIVSEPSDFRRELAKKVGADYVINPFEE 221 Query: 57 KTLFIQCDVADQQQLRDTFR 76 + D+ D + Sbjct: 222 DVVKEVMDITDGNGVDVFLE 241 >2CU0-A nrPDB Length = 486 Score = 31.4 bits (70), Expect = 0.36, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 24/60 (40%), Gaps = 1/60 (1%) Query: 22 AEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDT-FRKVVD 80 A L G V +VD ++ ++ E + FI ++A+ + + D F V Sbjct: 233 AIELDKAGVDVIVVDTAHAHNLKAIKSMKEMRQKVDADFIVGNIANPKAVDDLTFADAVK 292 >1QYC-A nrPDB Length = 308 Score = 31.4 bits (70), Expect = 0.36, Method: Composition-based stats. Identities = 24/122 (19%), Positives = 46/122 (37%), Gaps = 13/122 (10%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDW-NLEAGVQCKAALDEQFEPQKTLFIQCDV 65 L+ GA IGR A+A L G L+ + + KA L E F+ + + Sbjct: 6 RILLIGATGYIGRHVAKASLDLGHPTFLLVRESTASSNSEKAQLLESFKASGANIVHGSI 65 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMSKQ 125 D L + + +D++++ G ++ Q+N++ I + + Sbjct: 66 DDHASLVEAVKN-------VDVVISTVGSLQIES-----QVNIIKAIKEVGTVKRFFPSE 113 Query: 126 NG 127 G Sbjct: 114 FG 115 >1JPH-A nrPDB Length = 388 Score = 31.4 bits (70), Expect = 0.40, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 36/88 (40%), Gaps = 14/88 (15%) Query: 23 EALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV------ADQQQLRDTFR 76 E L G +V +DW + E KT+ +Q ++ A ++++ + Sbjct: 291 EELAQAGYEVVGLDWTV-----APKKARECV--GKTVTLQGNLDPCALYASEEEIGQLVK 343 Query: 77 KVVDHFGRLDILVN-NAGVNNEKNWEKT 103 +++D FG + N G+ + + E Sbjct: 344 QMLDDFGPHRYIANLGHGLYPDMDPEHV 371 >3SC6-A nrPDB Length = 287 Score = 31.0 bits (69), Expect = 0.47, Method: Composition-based stats. Identities = 24/168 (14%), Positives = 52/168 (30%), Gaps = 43/168 (25%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVA 66 ++TGA +G+ E L + + D L D+ Sbjct: 7 RVIITGANGQLGKQLQEELNPEEYDIYPFDKKL-----------------------LDIT 43 Query: 67 DQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMSKQN 126 + Q++ +++ R I+++ A EK + +G ++ + Sbjct: 44 NISQVQQVVQEI-----RPHIIIHCAAYTKVDQAEKERDL----AYVINAIGARNVAVAS 94 Query: 127 GGEGGIIINMSSLAGLMP-----------VAQQPVYCASKHGIVGFTR 163 G ++ +S+ A +Y ASK+ F + Sbjct: 95 QLVGAKLVYISTDYVFQGDRPEGYDEFHNPAPINIYGASKYAGEQFVK 142 >2C54-A nrPDB Length = 379 Score = 31.0 bits (69), Expect = 0.50, Method: Composition-based stats. Identities = 10/28 (35%), Positives = 12/28 (42%) Query: 10 VTGAAQGIGRAFAEALLLKGAKVALVDW 37 +TGA I A L +G V DW Sbjct: 34 ITGAGGFIASHIARRLKHEGHYVIASDW 61 >4EJ0-A nrPDB Length = 342 Score = 31.0 bits (69), Expect = 0.51, Method: Composition-based stats. Identities = 29/153 (18%), Positives = 51/153 (33%), Gaps = 17/153 (11%) Query: 9 LVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQ 68 +VTGAA IG +AL +G + NL + K +D C++ D Sbjct: 16 IVTGAAGFIGANLVKALNERGETRIIAVDNLTRADKFKNLVD------------CEIDDY 63 Query: 69 QQLRDTFRK-VVDHFGRLDILVNNAGVNN--EKNWEKTLQINLVSVISGTYLGLDYMSKQ 125 + + FG++ + + ++ E + + N + L ++ Sbjct: 64 LDKTEFVERFARGDFGKVRAVFHEGACSDTMETDGRYMMDNNFRYSRAVLDACLAQGAQF 123 Query: 126 NGGEGGIIINMSS--LAGLMPVAQQPVYCASKH 156 I SS + A VY SK Sbjct: 124 LYASSAAIYGGSSRFVEEREVEAPLNVYGYSKF 156 >2HK7-A nrPDB Length = 269 Score = 31.0 bits (69), Expect = 0.53, Method: Composition-based stats. Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAA 48 V K LV GA G RA AL+ +GAKV L + E ++ Sbjct: 121 VKEKSILVLGAG-GASRAVIYALVKEGAKVFLWNRTKEKAIKLAQK 165 >1ZDL-A nrPDB Length = 517 Score = 31.0 bits (69), Expect = 0.53, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 15/29 (51%), Gaps = 1/29 (3%) Query: 9 LVTGAAQGIGRAFAEALLLKGAKVALVDW 37 LV G G G A A+ G KVA+ D+ Sbjct: 36 LVIGGGSG-GLACAKEAAQLGKKVAVADY 63 >6GBN-A nrPDB Length = 438 Score = 31.0 bits (69), Expect = 0.54, Method: Composition-based stats. Identities = 13/44 (29%), Positives = 23/44 (52%), Gaps = 1/44 (2%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCK 46 + GKVA+V G +G+ A +L GA+V + + + +Q Sbjct: 217 MAGKVAVVAGYGD-VGKGSAASLRGAGARVIVTEIDPICALQAA 259 >4J90-A nrPDB Length = 222 Score = 31.0 bits (69), Expect = 0.57, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 22/62 (35%), Gaps = 11/62 (17%) Query: 16 GIGR---AFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLR 72 G+GR + + L G +V VD N E + T + + ++ +L Sbjct: 13 GLGRFGGSICKELHRMGHEVLAVDINEEKV--------NAYASYATHAVIANATEENELL 64 Query: 73 DT 74 Sbjct: 65 SL 66 >3H0K-A nrPDB Length = 178 Score = 30.6 bits (68), Expect = 0.63, Method: Composition-based stats. Identities = 16/49 (32%), Positives = 25/49 (51%), Gaps = 2/49 (4%) Query: 6 KVALVTGAAQGIGR-AFAEALLLKGAKVALVDWNLEAGVQCKAALDEQF 53 KV L+TG G G+ FA+ L +GAKV ++ + +A E+ Sbjct: 1 KVILITG-MPGSGKSEFAKLLKERGAKVIVMSDVVRKRYSIEAKPGERL 48 >4G2N-A nrPDB Length = 345 Score = 30.6 bits (68), Expect = 0.63, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 18/48 (37%), Gaps = 3/48 (6%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAA 48 M + G+ + G + IGRA A +G +A+ N Sbjct: 169 MGLTGRRLGIFGMGR-IGRAIATR--ARGFGLAIHYHNRTRLSHALEE 213 >2VN8-A nrPDB Length = 375 Score = 30.6 bits (68), Expect = 0.65, Method: Composition-based stats. Identities = 17/94 (18%), Positives = 33/94 (35%), Gaps = 15/94 (15%) Query: 4 NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63 GK L+ GA+ G+G FA ++ + + + L Sbjct: 183 TGKRVLILGASGGVG-TFAIQVMKA-WDAHVTAVCSQDASELVRKLGAD----------- 229 Query: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE 97 DV D + + + + D +++N G + E Sbjct: 230 DVIDYKS--GSVEEQLKSLKPFDFILDNVGGSTE 261 >1ZCJ-A nrPDB Length = 463 Score = 30.6 bits (68), Expect = 0.67, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 25/73 (34%), Gaps = 1/73 (1%) Query: 17 IGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFR 76 +GR A + G V V+ + + K + E + + Q A + F Sbjct: 48 MGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQASAKPKLR-FS 106 Query: 77 KVVDHFGRLDILV 89 +D++V Sbjct: 107 SSTKELSTVDLVV 119 >3JTM-A nrPDB Length = 351 Score = 30.6 bits (68), Expect = 0.67, Method: Composition-based stats. Identities = 20/99 (20%), Positives = 38/99 (38%), Gaps = 11/99 (11%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDW-------NLEAGVQCKAALDEQFE 54 + GK GA + IG+ + L G + D E G + L+E Sbjct: 161 DLEGKTIGTVGAGR-IGKLLLQRLKPFGCNLLYHDRLQMAPELEKETGAKFVEDLNEMLP 219 Query: 55 PQKTLFIQCDVADQQQLRDTF-RKVVDHFGRLDILVNNA 92 + I + ++ R F ++++ + ++VNNA Sbjct: 220 KCDVIVINMPLT--EKTRGMFNKELIGKLKKGVLIVNNA 256 >3F3S-A nrPDB Length = 313 Score = 30.6 bits (68), Expect = 0.67, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 30/71 (42%), Gaps = 3/71 (4%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAAL-DEQFEPQKTLF 60 + G V +V + IGR++A G +V L D + + E ++ Sbjct: 1 SMAGCVVIV--GSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGS 58 Query: 61 IQCDVADQQQL 71 ++ ++ ++QL Sbjct: 59 LKGSLSVEEQL 69 >4E0B-A nrPDB Length = 313 Score = 30.6 bits (68), Expect = 0.71, Method: Composition-based stats. Identities = 16/37 (43%), Positives = 21/37 (56%), Gaps = 4/37 (10%) Query: 6 KVALVTGAAQGIGRAFAEALLL---KGAKVALVDWNL 39 KVA++ GAA GIG+A A L G+ +AL D Sbjct: 5 KVAVI-GAAGGIGQALALLLKNRLPAGSDLALYDIAP 40 >3ZWA-A nrPDB Length = 742 Score = 30.6 bits (68), Expect = 0.72, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 25/73 (34%), Gaps = 1/73 (1%) Query: 17 IGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFR 76 +GR A + G V V+ + + K + E + + Q A + F Sbjct: 327 MGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQASAKPKLR-FS 385 Query: 77 KVVDHFGRLDILV 89 +D++V Sbjct: 386 SSTKELSTVDLVV 398 >3X2F-A nrPDB Length = 411 Score = 30.3 bits (67), Expect = 0.84, Method: Composition-based stats. Identities = 13/44 (29%), Positives = 19/44 (43%), Gaps = 3/44 (6%) Query: 3 VNGKVALVTGAAQG-IGRAFAEALLLKGAKVALVDWNLEAGVQC 45 V GK +V A G GR A GA+V + + + V+ Sbjct: 195 VAGKNVVV--AGYGWCGRGIALRAAGLGARVIVTEVDPVKAVEA 236 Score = 29.1 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 27/127 (21%), Positives = 46/127 (36%), Gaps = 20/127 (15%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 +H+ K A A L GAKV + N + + + E + Sbjct: 41 IHLEAKTAY-----------LAITLSKLGAKVVITGSNP---LSTQDDVAEALRSKGITV 86 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAG---VNNEKNWEKTLQINLVSVISGTYL 117 D+ R+ KV+D R D ++++ G V + E+ L+ NL V T Sbjct: 87 YARRTHDESIYRENLMKVLDE--RPDFIIDDGGDLTVISHTEREEVLE-NLKGVSEETTT 143 Query: 118 GLDYMSK 124 G+ + Sbjct: 144 GVRRLKA 150 >6BII-A nrPDB Length = 333 Score = 30.3 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 21/94 (22%), Positives = 41/94 (43%), Gaps = 9/94 (9%) Query: 5 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64 GK + G + IG+A A+ G ++ + + + + L +F+P + L + D Sbjct: 150 GKTIGIVGFGR-IGQAIAKRAKGFGMRILYTARSRK--PEAEKELGAEFKPLEELLRESD 206 Query: 65 --VADQQQLRDTFRKVVDHFGRL----DILVNNA 92 V ++T+ + + RL +LVN A Sbjct: 207 FVVLAVPLTKETYHMINEERLRLMKPTAVLVNVA 240 >3FFS-A nrPDB Length = 400 Score = 30.3 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 22/70 (31%), Gaps = 7/70 (10%) Query: 18 GRAF-------AEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQ 70 G A A+ L+ G V ++D + L E I +V ++ Sbjct: 138 GAAIGVNEIERAKLLVEAGVDVIVLDSAHGHSLNIIRTLKEIKSKMNIDVIVGNVVTEEA 197 Query: 71 LRDTFRKVVD 80 ++ D Sbjct: 198 TKELIENGAD 207 >3ZXS-A nrPDB Length = 522 Score = 29.9 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 23/74 (31%), Gaps = 9/74 (12%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALV-----DWNLEAGVQCKAALDEQFEPQKTLF 60 K+AL+ A + FA L +G +VA D G + E + Sbjct: 61 KIALILAAMR----KFARRLQERGFRVAYSRLDDPDTGPSIGAELLRRAAETGAREAVAT 116 Query: 61 IQCDVADQQQLRDT 74 D + L Sbjct: 117 RPGDWRLIEALEAM 130 >4QJ1-A nrPDB Length = 361 Score = 29.9 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 13/76 (17%), Positives = 25/76 (32%), Gaps = 9/76 (11%) Query: 14 AQGI--GRAF-------AEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64 + G+ G A A+ L+ G V ++D + L E I + Sbjct: 93 SGGLRVGAAIGVNEIERAKLLVEAGVDVIVLDSAHGHSLNIIRTLKEIKSKMNIDVIVGN 152 Query: 65 VADQQQLRDTFRKVVD 80 V ++ ++ D Sbjct: 153 VVTEEATKELIENGAD 168 >5XW3-A nrPDB Length = 315 Score = 29.9 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 20/109 (18%), Positives = 29/109 (26%), Gaps = 27/109 (24%) Query: 11 TGAAQGIGRAFA---------------------EALLLKGAKVALVDWNLEAGVQCKAAL 49 T GIG A A E + GA V + A Sbjct: 71 TAGNTGIGLALAALQHDLRVIVCVPEKFSIEKQELMKALGATVV-HTPTEQGMTGAIAKA 129 Query: 50 DEQFEPQKTLFIQCDVADQQQLRDTFRKVVDHF-----GRLDILVNNAG 93 E + A++ R F+ + G ++I V AG Sbjct: 130 KELVNEIPNSYSPSQFANEANPRAYFKTLGPELWSALNGEINIFVAGAG 178 >2CUK-A nrPDB Length = 311 Score = 29.9 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 30/80 (37%), Gaps = 1/80 (1%) Query: 13 AAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLR 72 IG+A A+ L G +V + +L+E + + + + + R Sbjct: 151 GMGRIGQAVAKRALAFGMRVVYHARTPKPLPYPFLSLEELLKEADVVSLHTPLT-PETHR 209 Query: 73 DTFRKVVDHFGRLDILVNNA 92 R+ + R IL+N A Sbjct: 210 LLNRERLFAMKRGAILLNTA 229 >4AP9-A nrPDB Length = 201 Score = 29.9 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 20/42 (47%) Query: 19 RAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 R E L KG KV L+ + E ++ L ++F + +F Sbjct: 85 RELVETLREKGFKVVLISGSFEEVLEPFKELGDEFMANRAIF 126 >6APE-A nrPDB Length = 298 Score = 29.9 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 19/120 (15%), Positives = 40/120 (33%), Gaps = 16/120 (13%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 + + GK + GA+ IG+ + +L GA V++ + D F Q Sbjct: 166 IEIKGKDVAIIGASNIIGKPLSMLMLNAGASVSVCHILTK---------DISFYTQNADI 216 Query: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLD 120 + V ++ + K +DI G+N+ + ++ + Sbjct: 217 VCVGVGKPDLIKASMLKKGAVV--VDI-----GINHLNDGRIVGDVDFTNAQKVAGFITP 269 >4OM8-A nrPDB Length = 309 Score = 29.9 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 25/75 (33%), Gaps = 1/75 (1%) Query: 17 IGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFR 76 +G A L G +V D A + ++ L L I A +R Sbjct: 13 MGPGMAARLARGGLQVVAYDVAPAAIERARSMLSVAETVLDALGIALPSAGVGTVR-FTD 71 Query: 77 KVVDHFGRLDILVNN 91 + D D+++ N Sbjct: 72 DIGDAVSGADLVIEN 86 >5MIO-C nrPDB Length = 573 Score = 29.5 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 23/70 (32%) Query: 19 RAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKV 78 E LL GA V+ D + A + + L DV DT ++ Sbjct: 456 LEIVEVLLKHGADVSASDLMGSTPLHLAALIGHLEIVEVLLKHGADVNAVDTWGDTPLRL 515 Query: 79 VDHFGRLDIL 88 G L I+ Sbjct: 516 AAVMGHLKIV 525 Score = 27.6 bits (60), Expect = 5.3, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 19/50 (38%), Gaps = 1/50 (2%) Query: 17 IG-RAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65 IG E LL GA V VD + ++ A + + L DV Sbjct: 486 IGHLEIVEVLLKHGADVNAVDTWGDTPLRLAAVMGHLKIVEALLKHGADV 535 >1EDZ-A nrPDB Length = 320 Score = 29.5 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 13/37 (35%), Positives = 18/37 (48%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWN 38 + GK +V ++ +GR A L GA V VD N Sbjct: 174 RLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVN 210 >3R9I-A nrPDB Length = 260 Score = 29.5 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 11/38 (28%), Positives = 19/38 (50%), Gaps = 5/38 (13%) Query: 6 KVALVTGAAQGIGR-----AFAEALLLKGAKVALVDWN 38 ++ +VT G+G+ A A L KG K ++D+ Sbjct: 3 RIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVIDFA 40 >3HDH-A nrPDB Length = 302 Score = 29.5 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 18/46 (39%), Gaps = 1/46 (2%) Query: 10 VTGAAQGI-GRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFE 54 VT G+ G A+ G V LVD + + K ++E Sbjct: 18 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLR 63 >2V6G-A nrPDB Length = 364 Score = 29.5 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 25/75 (33%), Gaps = 14/75 (18%) Query: 7 VALVTGAAQGIGRAFAEALLLK-----GAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 VAL+ G IG + AE L L KV V E ++ Sbjct: 3 VALIVGVTGIIGNSLAEILPLADTPGGPWKVYGVARRTRPAW---------HEDNPINYV 53 Query: 62 QCDVADQQQLRDTFR 76 QCD++D + Sbjct: 54 QCDISDPDDSQAKLS 68 >4BKP-A nrPDB Length = 336 Score = 29.5 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 26/79 (32%), Gaps = 25/79 (31%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ---C 63 LVTG + +G+A + ++ GA + +F+ Sbjct: 24 RILVTGGSGLVGKAI-QKVVADGA---------------------GLPGEDWVFVSSKDA 61 Query: 64 DVADQQQLRDTFRKVVDHF 82 D+ D Q R F KV Sbjct: 62 DLTDTAQTRALFEKVQPTH 80 >3R0Q-C nrPDB Length = 376 Score = 29.5 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 24/81 (29%), Gaps = 4/81 (4%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 H GK L G GI A GA+ + +A + I Sbjct: 61 HFEGKTVLDVGTGSGI---LAIWSAQAGARKVYAVEATKMADHARALVKANNLDHIVEVI 117 Query: 62 QCDVADQQQLRDTFRKVVDHF 82 + V D L + ++ + Sbjct: 118 EGSVEDI-SLPEKVDVIISEW 137 >1F14-A nrPDB Length = 310 Score = 29.5 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 18/46 (39%), Gaps = 1/46 (2%) Query: 10 VTGAAQGI-GRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFE 54 VT G+ G A+ G V LVD + + K ++E Sbjct: 18 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLR 63 >2WEK-A nrPDB Length = 341 Score = 29.5 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 14/41 (34%), Positives = 16/41 (39%), Gaps = 2/41 (4%) Query: 4 NGKVALVTGAAQGIGRAFAEALL-LKGAKVALVDWNLEAGV 43 GK LVT AA G G+ FA L V + E Sbjct: 142 EGKKVLVTAAAGGTGQ-FAMQLSKKAKCHVIGTCSSDEKSA 181 >1IE3-A nrPDB Length = 312 Score = 29.5 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 29/151 (19%), Positives = 48/151 (31%), Gaps = 19/151 (12%) Query: 6 KVALVTGAAQGIGRAFAEALLLK---GAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ 62 KVA V GAA GIG+A A L + G++++L D L K Sbjct: 2 KVA-VLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVT-PGVAVDLSHIPTAVKIKGFS 59 Query: 63 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEK--TLQINLVSVISGTYLGLD 120 D+++ +AGV + ++ +N V + Sbjct: 60 G------------EDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQVAK 107 Query: 121 YMSKQNGGEGGIIINMSSLAGLMPVAQQPVY 151 K G +N + + + VY Sbjct: 108 TCPKACIGIITNPVNTTVAIAAEVLKKAGVY 138 >3K6J-A nrPDB Length = 460 Score = 29.1 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 12/43 (27%), Positives = 19/43 (44%), Gaps = 2/43 (4%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAAL 49 VA++ G +G+A A L G + LV N + Q + Sbjct: 57 VAIIGGGT--MGKAMAICFGLAGIETFLVVRNEQRCKQELEVM 97 >5BUT-A nrPDB Length = 288 Score = 29.1 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 22/62 (35%), Gaps = 11/62 (17%) Query: 16 GIGR---AFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLR 72 G+GR + + L G +V VD N E + T + + ++ +L Sbjct: 13 GLGRFGGSIVKELHRMGHEVLAVDINEEKV--------NAYASYATHAVIANATEENELL 64 Query: 73 DT 74 Sbjct: 65 SL 66 Score = 29.1 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 22/62 (35%), Gaps = 11/62 (17%) Query: 16 GIGR---AFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLR 72 G+GR + + L G +V VD N E + T + + ++ +L Sbjct: 155 GLGRFGGSIVKELHRMGHEVLAVDINEEKV--------NAYASYATHAVIANATEENELL 206 Query: 73 DT 74 Sbjct: 207 SL 208 >4EJ6-A nrPDB Length = 370 Score = 29.1 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 15/89 (16%), Positives = 28/89 (31%), Gaps = 10/89 (11%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVA 66 VA++ G IG + L GA ++ + + D + Sbjct: 186 VAILGGGV--IGLLTVQLARLAGATTVILSTRQATKRRLAEEVGA--------TATVDPS 235 Query: 67 DQQQLRDTFRKVVDHFGRLDILVNNAGVN 95 + V G +D+++ AGV Sbjct: 236 AGDVVEAIAGPVGLVPGGVDVVIECAGVA 264 >2HMT-A nrPDB Length = 144 Score = 29.1 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 22/62 (35%), Gaps = 11/62 (17%) Query: 16 GIGR---AFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLR 72 G+GR + + L G +V VD N E + T + + ++ +L Sbjct: 13 GLGRFGGSIVKELHRMGHEVLAVDINEEKV--------NAYASYATHAVIANATEENELL 64 Query: 73 DT 74 Sbjct: 65 SL 66 >4B4O-A nrPDB Length = 298 Score = 29.1 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 14/49 (28%), Positives = 17/49 (34%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEP 55 LV G IG A + L +G +V LV G L P Sbjct: 2 RVLVGGGTGFIGTALTQLLNARGHEVTLVSRKPGPGRITWDELAASGLP 50 >5AQB-A nrPDB Length = 428 Score = 29.1 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 24/89 (26%), Positives = 31/89 (34%), Gaps = 4/89 (4%) Query: 19 RAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKV 78 E LL GA V D + + A + L DV Q T + Sbjct: 59 LEIVECLLKNGADVNAADIDGYTPLHLAAFSGHLEIVEVLLKYGADVNADDQAGFTPLHL 118 Query: 79 VDHFGRLDI----LVNNAGVNNEKNWEKT 103 FG L+I L N A VN + + KT Sbjct: 119 AAIFGHLEIVEVLLKNGADVNAQDKFGKT 147 >6C6P-A nrPDB Length = 458 Score = 29.1 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 32/73 (43%), Gaps = 5/73 (6%) Query: 8 ALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVAD 67 ++ GA +G A A L G KV +++ +L+ + + E +P ++ D+ Sbjct: 10 VIIVGAGV-LGSALAAVLSRDGRKVTVIERDLK---EPDRIVGEFLQPGGYHVLK-DLGL 64 Query: 68 QQQLRDTFRKVVD 80 + +VV+ Sbjct: 65 GDTVEGLDAQVVN 77 >6BZC-A nrPDB Length = 555 Score = 29.1 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 29/69 (42%), Gaps = 4/69 (5%) Query: 39 LEAGVQCKAALDEQFEPQKTL--FIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN 96 + Q AL E+ + D+ +Q + R + +FG I+VN G + Sbjct: 67 DKKAFQLLLALAEECHLNDAIEKMFTGDLINQTENRAVLHTALRNFGEEKIVVN--GKSI 124 Query: 97 EKNWEKTLQ 105 +++ ++ L Sbjct: 125 DEDVQRVLN 133 >1QQV-A nrPDB Length = 67 Score = 28.7 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 19/52 (36%), Gaps = 9/52 (17%) Query: 84 RLDILVNNA------GVNNEKNWEKTLQINLVSVISGTYLG---LDYMSKQN 126 LD+LVN A GV+ + + +V T L +QN Sbjct: 8 PLDVLVNTAAEDLPRGVDPSRKENHLSDEDFKAVFGMTRSAFANLPLWKQQN 59 >6H5E-B nrPDB Length = 437 Score = 28.7 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 10/20 (50%), Positives = 14/20 (70%) Query: 72 RDTFRKVVDHFGRLDILVNN 91 + FR +D FG +DI+VNN Sbjct: 129 TNFFRDQMDRFGEIDIMVNN 148 >2OWO-A nrPDB Length = 671 Score = 28.7 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 30/74 (40%), Gaps = 3/74 (4%) Query: 3 VNGKVALVTGAAQGIGRAFAE-ALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 GK ++TG+ + R A+ L+ GAKVA V A + + L I Sbjct: 598 FAGKTVVLTGSLSQMSRDDAKARLVELGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGI 657 Query: 62 QCDVADQQQLRDTF 75 + V D+ ++ Sbjct: 658 E--VIDEAEMLRLL 669 >2D0I-A nrPDB Length = 333 Score = 28.7 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 26/64 (40%), Gaps = 3/64 (4%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 + GK + G IG+A A L+ G V L W+ V + L ++ L Sbjct: 143 SLYGKKVGILG-MGAIGKAIARRLIPFG--VKLYYWSRHRKVNVEKELKARYMDIDELLE 199 Query: 62 QCDV 65 + D+ Sbjct: 200 KSDI 203 >5XF9-D nrPDB Length = 468 Score = 28.7 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 14/32 (43%) Query: 136 MSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167 + S V Q V A+K + G T + AL Sbjct: 417 IVSTTHNNAVMNQAVTTAAKAFLSGVTLTEAL 448 >3L07-A nrPDB Length = 285 Score = 28.7 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 25/72 (34%), Gaps = 1/72 (1%) Query: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEP-QKTL 59 + G A+V GA+ +G+ ++ LL A V D K Sbjct: 157 IKTEGAYAVVVGASNVVGKPVSQLLLNAKATVTTCHRFTTDLKSHTTKADILIVAVGKPN 216 Query: 60 FIQCDVADQQQL 71 FI D+ + + Sbjct: 217 FITADMVKEGAV 228 >1NHQ-A nrPDB Length = 447 Score = 28.7 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 15/31 (48%), Gaps = 2/31 (6%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDW 37 V ++ + IG AEA G KV ++D Sbjct: 152 VVVI--GSGYIGIEAAEAFAKAGKKVTVIDI 180 >4A5O-A nrPDB Length = 286 Score = 28.7 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 13/43 (30%), Positives = 18/43 (41%) Query: 8 ALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALD 50 A+V GA+ +GR A LLL G V + + D Sbjct: 164 AVVVGASNIVGRPMALELLLGGCTVTVTHRFTRDLADHVSRAD 206 >3K30-A nrPDB Length = 690 Score = 28.3 bits (62), Expect = 3.1, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 25/69 (36%), Gaps = 4/69 (5%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAG---VQCKAALDEQFEPQKTLFIQC 63 LV GA G A AL ++G V L + + G Q A + + + Sbjct: 393 RVLVVGAGPS-GLEAARALGVRGYDVVLAEAGRDLGGRVTQESALPGLSAWGRVKEYREA 451 Query: 64 DVADQQQLR 72 +A+ + Sbjct: 452 VLAELPNVE 460 >5OCM-A nrPDB Length = 291 Score = 28.3 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 28/80 (35%), Gaps = 8/80 (10%) Query: 17 IGRAFAEALLLKGAKVALVDWNLEAGVQCK------AALDEQFEPQKTLFIQCDVADQQQ 70 +G+A A A L G + + + Q A+ L + C V+D Sbjct: 14 MGQALAGAFLKDGHATTVWNRSEGKAGQLAEQGAVLASSARDAAEASPLVVVC-VSDHAA 72 Query: 71 LRDTFRKVVDHFGRLDILVN 90 +R + D +LVN Sbjct: 73 VRAVLDPLGDVLAG-RVLVN 91 >4B3J-A nrPDB Length = 736 Score = 28.3 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 22/107 (20%), Positives = 39/107 (36%), Gaps = 23/107 (21%) Query: 13 AAQGIGRAFAEALLLKGAKVALVDWNLEAGV---------QCKAALDEQFEPQKTLFI-- 61 A +G A G +V L D +LEA + KA + +++ + Sbjct: 348 GAGMMGAGIAYVSAKAGYEVVLKDVSLEAAAKGKGYSEKLEAKALERGRTTQERSDALLA 407 Query: 62 ----QCDVADQQQLRDTFRKVVDH-------FGRL-DILVNNAGVNN 96 D AD + + V ++ FG + DI+ NA + + Sbjct: 408 RITPTADAADFKGVDFVIEAVFENQELKHKVFGEIEDIVEPNAILGS 454 >2VS1-A nrPDB Length = 425 Score = 28.3 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 18/108 (16%), Positives = 35/108 (32%), Gaps = 24/108 (22%) Query: 76 RKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIIN 135 + + +D L++ Q N ++ + + EG I++ Sbjct: 252 EFIRERLDDVDYLIH---------PNSFFQTNSYQAVNLVRKVSELV------EGEKILD 296 Query: 136 MSSLAGLMPVAQQPVYCASKHG--IVGFTRSAALAANLMNSGVRLNAI 181 M S G + +K G + GF S A + V +N + Sbjct: 297 MYSGVGTFGIYL------AKRGFNVKGF-DSNEFAIEMARRNVEINNV 337 >4R16-A nrPDB Length = 418 Score = 28.3 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 13/40 (32%) Query: 17 IGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQ 56 IG A G V D E + + + EP+ Sbjct: 11 IGLPTAIMFASSGYDVVGYDIRSEVIKKINSGVAHIIEPE 50 >1BW9-B nrPDB Length = 356 Score = 28.3 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 24/64 (37%), Gaps = 1/64 (1%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFI 61 ++G LV G +G + A GA++ + D + E A + L Sbjct: 173 SLDGLTVLVQGLGA-VGGSLASLAAEAGAQLLVADTDTERVAHAVALGHTAVALEDVLST 231 Query: 62 QCDV 65 CDV Sbjct: 232 PCDV 235 >2YQ5-A nrPDB Length = 343 Score = 28.3 bits (62), Expect = 3.6, Method: Composition-based stats. Identities = 10/20 (50%), Positives = 10/20 (50%) Query: 17 IGRAFAEALLLKGAKVALVD 36 IG A AE GAKV D Sbjct: 159 IGSAVAEIFSAMGAKVIAYD 178 >1P0K-A nrPDB Length = 349 Score = 28.3 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 34/260 (13%), Positives = 74/260 (28%), Gaps = 52/260 (20%) Query: 11 TGAAQG----IGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQ-CDV 65 TG I ++ A A G +A+ + E + + ++ Sbjct: 64 TGGGGKLTYEINKSLARAASQAGIPLAVGSQMSALKDPSERLSYEIVRKENPNGLIFANL 123 Query: 66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMSKQ 125 + ++ V+ G NA + +N++ I + + Sbjct: 124 GSEATAAQA-KEAVEMIG------ANA---------LQIHLNVIQEI-----VMPEGDRS 162 Query: 126 NGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGF 185 G I + S + + ++ + SK + A A ++ G Sbjct: 163 FSGALKRIEQICSRVSVPVIVKEVGFGMSKASAGKLYEAGAAAVDIGGYG---------- 212 Query: 186 VNTAI--LESIEKEENM-----------GQYIEYKDHIKD--MIKYYGILDPPLIANGLI 230 T +E++ ++ + E + MI G+ D +A + Sbjct: 213 -GTNFSKIENLRRQRQISFFNSWGISTAASLAEIRSEFPASTMIASGGLQDALDVAKAIA 271 Query: 231 TLIEDDALNGAIMKITTSKG 250 + G +K T G Sbjct: 272 LGASCTGMAGHFLKALTDSG 291 >1YB5-A nrPDB Length = 351 Score = 28.3 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 16/37 (43%) Query: 5 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEA 41 G+ LV GA+ G+G A + G K+ E Sbjct: 171 GESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEG 207 >5XVM-A nrPDB Length = 478 Score = 28.3 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 13/81 (16%), Positives = 31/81 (38%), Gaps = 9/81 (11%) Query: 68 QQQLRDTFRKVVDHFGRL------DILVNNAGVNNEKNWEKTLQINLVSVIS---GTYLG 118 +L++ + +L I+V+NA E E ++ ++ +++ LG Sbjct: 254 PAELQEFISEARSKGKKLVYIGFGSIVVSNAKEMTEALVEAVMEADVYCILNKGWSERLG 313 Query: 119 LDYMSKQNGGEGGIIINMSSL 139 K I+N+ ++ Sbjct: 314 DKAAKKTEVDLPRNILNIGNV 334 >2BC1-A nrPDB Length = 490 Score = 28.0 bits (61), Expect = 4.0, Method: Composition-based stats. Identities = 14/31 (45%), Positives = 18/31 (58%), Gaps = 2/31 (6%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVD 36 +VA+V A IG AEA KG +V L+D Sbjct: 196 RVAVV--GAGYIGVELAEAFQRKGKEVVLID 224 >1WDK-C nrPDB Length = 390 Score = 28.0 bits (61), Expect = 4.2, Method: Composition-based stats. Identities = 8/27 (29%), Positives = 14/27 (51%) Query: 136 MSSLAGLMPVAQQPVYCASKHGIVGFT 162 +S + G+ P +Y A G++G T Sbjct: 127 VSMMHGVDPNPHMSLYAAKASGMMGLT 153 >3ZU2-A nrPDB Length = 422 Score = 28.0 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 22/96 (22%), Positives = 34/96 (35%), Gaps = 13/96 (13%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKV----ALVDWNLEAGVQ-----CKAALDEQFEPQ 56 K LV GA+ G G A A G + E G +A +F Q Sbjct: 65 KRVLVIGASTGYGLA-ARITAAFGCGADTLGVFFERPGEEGKPGTSGWYNSAAFHKFAAQ 123 Query: 57 KTLF---IQCDVADQQQLRDTFRKVVDHFGRLDILV 89 K L+ I D + + T + G++D ++ Sbjct: 124 KGLYAKSINGDAFSDEIKQLTIDAIKQDLGQVDQVI 159 >5TC4-A nrPDB Length = 316 Score = 28.0 bits (61), Expect = 4.9, Method: Composition-based stats. Identities = 9/27 (33%), Positives = 13/27 (48%) Query: 5 GKVALVTGAAQGIGRAFAEALLLKGAK 31 GK +V G ++ +G A L GA Sbjct: 159 GKNVVVAGRSKNVGMPIAMLLHTDGAH 185 >4DGS-A nrPDB Length = 340 Score = 28.0 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 22/90 (24%), Positives = 33/90 (36%), Gaps = 2/90 (2%) Query: 4 NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63 GK V G Q IGRA A G V + + +GV A + + + Sbjct: 170 KGKRIGVLGLGQ-IGRALASRAEAFGMSVRYWNRSTLSGVDWIAHQSPVDLARDSDVLAV 228 Query: 64 DVADQQQLRDTFRK-VVDHFGRLDILVNNA 92 VA ++ ++ G I+VN A Sbjct: 229 CVAASAATQNIVDASLLQALGPEGIVVNVA 258 >1IHU-A nrPDB Length = 589 Score = 28.0 bits (61), Expect = 5.1, Method: Composition-based stats. Identities = 9/34 (26%), Positives = 12/34 (35%), Gaps = 5/34 (14%) Query: 13 AAQGIGR-----AFAEALLLKGAKVALVDWNLEA 41 G+G+ A A L G V L + A Sbjct: 334 GKGGVGKTTMAAAIAVRLADMGFDVHLTTSDPAA 367 >2NX9-A nrPDB Length = 464 Score = 28.0 bits (61), Expect = 5.1, Method: Composition-based stats. Identities = 14/89 (15%), Positives = 38/89 (42%), Gaps = 7/89 (7%) Query: 183 PGFVNTAILESIEKEENMGQ---YIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALN 239 PG + T + ++++ + + +E +++ + + ++ P + + T + + Sbjct: 301 PGGMLTNMESQLKQQNALDKLDLVLEEIPRVREELGFLPLVTPT--SQIVGTQAVINVVL 358 Query: 240 GAIMKITT--SKGIHFQDYDTTPFQAKTQ 266 G K T + G+ +Y TP T+ Sbjct: 359 GERYKTITKETSGVLKGEYGKTPAPVNTE 387 >4LSW-A nrPDB Length = 318 Score = 28.0 bits (61), Expect = 5.2, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 35/91 (38%), Gaps = 3/91 (3%) Query: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFE-PQKTLF 60 V G+ A V G + IG A L +++ D ++ +++ + F Sbjct: 142 RVFGRRAGVLGLGR-IGFEVARRLAGFDMQISYSDIAPKSYAPDWTFVEDAVTLARDVDF 200 Query: 61 IQCDVADQQQLRDTF-RKVVDHFGRLDILVN 90 + +A R R V++ G +L+N Sbjct: 201 LFVTLAASAATRHIVGRDVIEALGPEGMLIN 231 >2JLA-A nrPDB Length = 558 Score = 27.6 bits (60), Expect = 5.4, Method: Composition-based stats. Identities = 11/39 (28%), Positives = 16/39 (41%), Gaps = 1/39 (2%) Query: 163 RSAALAAN-LMNSGVRLNAICPGFVNTAILESIEKEENM 200 R AA+ L GVR I PG +T + + + Sbjct: 11 RWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAF 49 >3GWG-A nrPDB Length = 129 Score = 27.6 bits (60), Expect = 5.4, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 23/58 (39%), Gaps = 4/58 (6%) Query: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYM 122 V D +R + + G D+L GV + WEK L N + + T + M Sbjct: 11 VDDSSTMRRIIKNTLSRLGYEDVLEAEHGV---EAWEK-LDANADTKVLITDWNMPEM 64 >2XHZ-A nrPDB Length = 183 Score = 27.6 bits (60), Expect = 5.9, Method: Composition-based stats. Identities = 10/27 (37%), Positives = 13/27 (48%), Gaps = 1/27 (3%) Query: 4 NGKVALV-TGAAQGIGRAFAEALLLKG 29 GKV ++ GA+ IGR A G Sbjct: 49 KGKVVVMGMGASGHIGRKMAATFASTG 75 >4K22-A nrPDB Length = 365 Score = 27.6 bits (60), Expect = 6.2, Method: Composition-based stats. Identities = 12/41 (29%), Positives = 21/41 (51%), Gaps = 2/41 (4%) Query: 7 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKA 47 VA+V G +G A A L G +VA+++ ++ + A Sbjct: 6 VAIVGGGM--VGLAVACGLQGSGLRVAVLEQRVQEPLAANA 44 >3PDU-A nrPDB Length = 287 Score = 27.6 bits (60), Expect = 6.3, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 17/52 (32%), Gaps = 1/52 (1%) Query: 16 GI-GRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVA 66 GI G A L+ G V + + N A Q + CD+ Sbjct: 10 GIMGGPMAANLVRAGFDVTVWNRNPAKCAPLVALGARQASSPAEVCAACDIT 61 >3FBG-A nrPDB Length = 346 Score = 27.6 bits (60), Expect = 6.4, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 15/38 (39%), Gaps = 2/38 (5%) Query: 4 NGKVALVTGAAQGIGRAFAEALLLK-GAKVALVDWNLE 40 GK L+ A G+G + A + G +V E Sbjct: 150 EGKTLLIINGAGGVG-SIATQIAKAYGLRVITTASRNE 186 >5KIA-A nrPDB Length = 351 Score = 27.6 bits (60), Expect = 6.5, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 28/71 (39%), Gaps = 9/71 (12%) Query: 1 MHVNGKVALVTGAAQGIG---RAFAEALLLKGAKVALVDWN---LEAGVQCKAALDEQFE 54 ++ G+ L+TGA IG A A+ + + V + D N L+ + A Sbjct: 168 FNLVGEDVLITGAGP-IGVMAVAIAKHVGAR--NVVITDINDYRLDLARRMGATRAVNVS 224 Query: 55 PQKTLFIQCDV 65 + + D+ Sbjct: 225 RESLRDVMADL 235 >4GBJ-A nrPDB Length = 297 Score = 27.2 bits (59), Expect = 7.0, Method: Composition-based stats. Identities = 15/91 (16%), Positives = 33/91 (36%), Gaps = 14/91 (15%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKA--------ALDEQFE 54 ++ K+A + +G AE LL G ++ + + A+D Sbjct: 4 MSEKIAFL--GLGNLGTPIAEILLEAGYELVVWNRTASKAEPLTKLGATVVENAIDAITP 61 Query: 55 PQKTLFIQCDVADQQQLRDTFR-KVVDHFGR 84 + +AD + + F ++V+ G+ Sbjct: 62 GGIVFSV---LADDAAVEELFSMELVEKLGK 89 >5W4Y-A nrPDB Length = 461 Score = 27.2 bits (59), Expect = 7.4, Method: Composition-based stats. Identities = 7/37 (18%), Positives = 15/37 (40%) Query: 219 ILDPPLIANGLITLIEDDALNGAIMKITTSKGIHFQD 255 + P +A+ ++ L E L+G ++ G Sbjct: 372 VGTPEEVADAIVELAEGADLDGFLLTPVIQPGSTIDF 408 >1G3N-B nrPDB Length = 168 Score = 27.2 bits (59), Expect = 8.0, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 24/69 (34%) Query: 20 AFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVV 79 A LLL+GA L D A + A Q L Q DV + + + Sbjct: 51 EIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110 Query: 80 DHFGRLDIL 88 G L ++ Sbjct: 111 AKEGHLRVV 119 >2DQ4-A nrPDB Length = 343 Score = 27.2 bits (59), Expect = 8.4, Method: Composition-based stats. Identities = 12/28 (42%), Positives = 15/28 (53%), Gaps = 1/28 (3%) Query: 3 VNGKVALVTGAAQGIGRAFAEALLLKGA 30 V+GK L+TGA IG A + GA Sbjct: 163 VSGKSVLITGAGP-IGLMAAMVVRASGA 189 >3VVL-A nrPDB Length = 394 Score = 26.8 bits (58), Expect = 8.9, Method: Composition-based stats. Identities = 19/68 (27%), Positives = 26/68 (38%), Gaps = 8/68 (11%) Query: 1 MHVNGKVALVTGAAQGI------GRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFE 54 M V ALV GA I + A+ L GA V+ + + AG E+F Sbjct: 326 MRVE--RALVMGARTDILFPLSQQQEIADGLSAGGADVSFLPVDTPAGHDAFLVDIERFG 383 Query: 55 PQKTLFIQ 62 P F+ Sbjct: 384 PPVAKFLA 391 >2RIR-A nrPDB Length = 300 Score = 26.8 bits (58), Expect = 9.0, Method: Composition-based stats. Identities = 7/35 (20%), Positives = 11/35 (31%), Gaps = 3/35 (8%) Query: 16 GIGRA---FAEALLLKGAKVALVDWNLEAGVQCKA 47 G+GR A GA V + + + Sbjct: 164 GLGRTGMTIARTFAALGANVKVGARSSAHLARITE 198 >2R5U-A nrPDB Length = 200 Score = 26.8 bits (58), Expect = 9.0, Method: Composition-based stats. Identities = 11/58 (18%), Positives = 19/58 (32%), Gaps = 6/58 (10%) Query: 19 RAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFR 76 +A L+ G +V + G +D + DVAD++ D Sbjct: 129 KALLRRLVEAGTRVVQYGYAGAEGADVAEVVD------RAQAEIYDVADRRLSEDFVA 180 >6BMQ-A nrPDB Length = 523 Score = 26.8 bits (58), Expect = 9.2, Method: Composition-based stats. Identities = 7/24 (29%), Positives = 12/24 (50%) Query: 27 LKGAKVALVDWNLEAGVQCKAALD 50 KGAKV + + E ++ A+ Sbjct: 385 EKGAKVVIANRTYERALELAEAIG 408 >4PZE-A nrPDB Length = 284 Score = 26.8 bits (58), Expect = 9.2, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 20/45 (44%), Gaps = 1/45 (2%) Query: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALD 50 + + GA +G A+A + G V +VD + A + A + Sbjct: 4 RTVGIVGAGT-MGNGIAQACAVVGLNVVMVDISDAAVQKGVATVA 47 >3DDL-A nrPDB Length = 273 Score = 26.8 bits (58), Expect = 9.2, Method: Composition-based stats. Identities = 8/43 (18%), Positives = 13/43 (30%) Query: 18 GRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60 G A+ L G V + + + + E EP Sbjct: 231 GYTIADVLAKAGYGVLIYNIAKAKSEEEGFNVSEMVEPATASA 273 >4N72-A nrPDB Length = 249 Score = 26.8 bits (58), Expect = 9.4, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 27/67 (40%), Gaps = 6/67 (8%) Query: 105 QINLVSVISGTYLGLDYMSKQNGGE------GGIIINMSSLAGLMPVAQQPVYCASKHGI 158 +N +I + + K G+ G +SS+ GL P+ A + I Sbjct: 132 DVNKKGIIELSRELMTISKKARDGKLTAGEMQGGCFTISSIGGLGTTHFAPIVNAPEVAI 191 Query: 159 VGFTRSA 165 +G ++SA Sbjct: 192 LGVSKSA 198 >5LJ6-A nrPDB Length = 664 Score = 26.8 bits (58), Expect = 9.5, Method: Composition-based stats. Identities = 15/131 (11%), Positives = 41/131 (31%), Gaps = 23/131 (17%) Query: 20 AFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVV 79 L +G + +V + ++ + I D ++Q++ + Sbjct: 204 EILRQLHEEGHTIIMVTHDKHIAASANRIIEIKDGE-----IISD-TQKRQVKSAVKNPS 257 Query: 80 DHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGL-DYMSKQNGGEGGIIINMSS 138 GR G + ++ L+ + + + + GIII ++S Sbjct: 258 VFKGRF-------GFSKDQ---------LMEAFRMSVSAIVAHKMRSLLTMLGIIIGITS 301 Query: 139 LAGLMPVAQQP 149 + ++ + Sbjct: 302 VVSVVALGNGS 312 >5A3V-A nrPDB Length = 329 Score = 26.8 bits (58), Expect = 9.7, Method: Composition-based stats. Identities = 18/63 (28%), Positives = 24/63 (38%), Gaps = 8/63 (12%) Query: 4 NGKVA--LVTGAAQGIGRAFAEALLL-KGAKVALV--DWNLE--AGVQCKAALDEQFEPQ 56 GK A LVT A+ G+G +A L A V N+E + LD + Sbjct: 153 TGKKANILVTAASGGVG-HYAVQLAKLANAHVTATCGARNIEFVKSLGADEVLDYKTPEG 211 Query: 57 KTL 59 L Sbjct: 212 AAL 214 >4NEC-A nrPDB Length = 264 Score = 26.8 bits (58), Expect = 10.0, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 20/59 (33%), Gaps = 2/59 (3%) Query: 22 AEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVVD 80 A L G V +D + A + D + +F D D + F V+D Sbjct: 74 ALHLAGLGYAVTGLDLSPTAISVARDKADAR--GLGAVFEVADALDLTGWEERFDTVID 130 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.149 0.420 Lambda K H 0.267 0.0460 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,805,658 Number of Sequences: 36641 Number of extensions: 449540 Number of successful extensions: 3451 Number of sequences better than 10.0: 431 Number of HSP's better than 10.0 without gapping: 429 Number of HSP's successfully gapped in prelim test: 181 Number of HSP's that attempted gapping in prelim test: 1869 Number of HSP's gapped (non-prelim): 668 length of query: 266 length of database: 10,336,785 effective HSP length: 95 effective length of query: 171 effective length of database: 6,855,890 effective search space: 1172357190 effective search space used: 1172357190 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 59 (27.2 bits)