BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P15311 (586 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4RM9-A nrPDB 1198 0.0 2I1J-A nrPDB 645 0.0 4RMA-A nrPDB 630 0.0 1E5W-A nrPDB 607 e-174 2EMT-A nrPDB 592 e-169 4YL8-A nrPDB 557 e-159 4ZRI-A nrPDB 405 e-113 6IBE-A nrPDB 143 2e-34 1GG3-A nrPDB 141 8e-34 6D2Q-A nrPDB 127 1e-29 1EF1-C nrPDB 127 2e-29 6D2K-A nrPDB 120 1e-27 6D21-A nrPDB 120 1e-27 2RQ1-A nrPDB 67 2e-11 3IVF-A nrPDB 53 3e-07 1MK7-B nrPDB 52 6e-07 3G9W-A nrPDB 50 2e-06 4F7G-A nrPDB 50 3e-06 2HRJ-A nrPDB 47 2e-05 5MV9-A nrPDB 40 0.002 5D68-A nrPDB 40 0.002 3PZD-A nrPDB 40 0.004 4HDO-A nrPDB 39 0.004 4ZRJ-B nrPDB 38 0.014 3QR5-A nrPDB 31 1.3 3JAX-A nrPDB 30 2.8 1YIO-A nrPDB 29 5.0 1ZXE-A nrPDB 29 6.0 6C2V-A nrPDB 28 8.0 2NRA-C nrPDB 28 8.2 4ZPX-A nrPDB 28 9.0 >4RM9-A nrPDB Length = 587 Score = 1198 bits (3100), Expect = 0.0, Method: Compositional matrix adjust. Identities = 586/586 (100%), Positives = 586/586 (100%) Query: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLK 60 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLK Sbjct: 2 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLK 61 Query: 61 LDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPE 120 LDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPE Sbjct: 62 LDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPE 121 Query: 121 TAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHR 180 TAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHR Sbjct: 122 TAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHR 181 Query: 181 GMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGF 240 GMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGF Sbjct: 182 GMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGF 241 Query: 241 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTI 300 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTI Sbjct: 242 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTI 301 Query: 301 EVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKK 360 EVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKK Sbjct: 302 EVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKK 361 Query: 361 AERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAE 420 AERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAE Sbjct: 362 AERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAE 421 Query: 421 LAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEP 480 LAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEP Sbjct: 422 LAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEP 481 Query: 481 VSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQRQLLTLSSELSQ 540 VSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQRQLLTLSSELSQ Sbjct: 482 VSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQRQLLTLSSELSQ 541 Query: 541 ARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEAL 586 ARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEAL Sbjct: 542 ARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEAL 587 >2I1J-A nrPDB Length = 575 Score = 645 bits (1664), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/602 (56%), Positives = 433/602 (71%), Gaps = 43/602 (7%) Query: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLK 60 MPK +NVRVTTMDAELEFAIQ TTGKQLFDQVVKTIGLREVW+FGL Y D+KG TW+K Sbjct: 1 MPKSMNVRVTTMDAELEFAIQQTTTGKQLFDQVVKTIGLREVWFFGLQYTDSKGDLTWIK 60 Query: 61 LDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPE 120 L KKV Q+V+KENPLQFKFRAKFYPEDVA+ELIQ+IT KLF+LQVK ILSDEIYCPPE Sbjct: 61 LYKKVMQQDVKKENPLQFKFRAKFYPEDVADELIQEITLKLFYLQVKNAILSDEIYCPPE 120 Query: 121 TAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHR 180 T+VLL SYAVQA+ GD+N VH G+L+++RL+PQRV DQHK++R++WE I W EHR Sbjct: 121 TSVLLASYAVQARHGDHNPAVHGPGFLANDRLLPQRVTDQHKMSREEWEQSITNWWQEHR 180 Query: 181 GMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGF 240 GML+++AM+EYLKIAQDLEMYG+NYFEI+NKK T+LWLGVDALGLNIYEKDDKLTPKIGF Sbjct: 181 GMLREDAMMEYLKIAQDLEMYGVNYFEIRNKKNTELWLGVDALGLNIYEKDDKLTPKIGF 240 Query: 241 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTI 300 PWSEIRNISFND+KF+IKPIDKKAPDFVF+APR+R+NKRIL LCMGNHELYMRRRKPDTI Sbjct: 241 PWSEIRNISFNDRKFIIKPIDKKAPDFVFFAPRVRVNKRILALCMGNHELYMRRRKPDTI 300 Query: 301 EVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKK 360 +VQQMKAQAREEK KQ +R++L+ E RE E ++++E RL+ +E+ ++ Sbjct: 301 DVQQMKAQAREEKLAKQAQREKLQLEIAARERAE-------KKQQEYQDRLRQMQEEMER 353 Query: 361 AERELSEQIQRALQLEEERKRAQEEAERLE---------ADRMAALRAKEELERQAV-DQ 410 ++ L E L+LEE+ ++ Q E LE R+ + E ERQ + D+ Sbjct: 354 SQANLLEAQDMILRLEEQLRQLQAAKEELEQRQNELQAMMQRLEETKNMEAAERQKLEDE 413 Query: 411 IKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVK------TKEELH 464 I+++++ E++ ++ L + RR ++EVE+ A+ QD+ T + H Sbjct: 414 IRAKQE---EVSRIQQEVELKDSETRRLQEEVED----ARRKQDEAAAALLAATTPQHHH 466 Query: 465 LVMTAPPPPPPPVYEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKN 524 + A P ++ D G+E G + + D + R T AE+N Sbjct: 467 VAERADTDPD-----------HDNASDAGSESGGGDLARGPDDLVDPVAD--RRTLAERN 513 Query: 525 ERVQRQLLTLSSELSQARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFE 584 ER+ QL L +L+++ DE K T D IH EN+RQGRDKYKTLR+IR+GNTK+R+D+FE Sbjct: 514 ERLHNQLKALKQDLARSCDETKETAMDKIHRENVRQGRDKYKTLREIRKGNTKRRVDQFE 573 Query: 585 AL 586 + Sbjct: 574 NM 575 >4RMA-A nrPDB Length = 296 Score = 630 bits (1625), Expect = 0.0, Method: Compositional matrix adjust. Identities = 296/296 (100%), Positives = 296/296 (100%) Query: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLK 60 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLK Sbjct: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLK 60 Query: 61 LDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPE 120 LDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPE Sbjct: 61 LDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPE 120 Query: 121 TAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHR 180 TAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHR Sbjct: 121 TAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHR 180 Query: 181 GMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGF 240 GMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGF Sbjct: 181 GMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGF 240 Query: 241 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRK 296 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRK Sbjct: 241 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRK 296 >1E5W-A nrPDB Length = 346 Score = 607 bits (1565), Expect = e-174, Method: Compositional matrix adjust. Identities = 278/325 (85%), Positives = 310/325 (95%) Query: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLK 60 MPK I+VRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVW+FGL Y D KGF TWLK Sbjct: 1 MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLK 60 Query: 61 LDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPE 120 L+KKV+AQ+VRKE+PL FKFRAKFYPEDV+EELIQDITQ+LFFLQVKEGIL+D+IYCPPE Sbjct: 61 LNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPE 120 Query: 121 TAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHR 180 TAVLL SYAVQ+K+GD+NKEVHKSGYL+ ++L+PQRV++QHKL +DQWE+RIQVWH EHR Sbjct: 121 TAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHR 180 Query: 181 GMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGF 240 GML+++A+LEYLKIAQDLEMYG+NYF IKNKKG++LWLGVDALGLNIYE++D+LTPKIGF Sbjct: 181 GMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGF 240 Query: 241 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTI 300 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRIL LCMGNHELYMRRRKPDTI Sbjct: 241 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI 300 Query: 301 EVQQMKAQAREEKHQKQLERQQLET 325 EVQQMKAQAREEKHQKQ+ER LE Sbjct: 301 EVQQMKAQAREEKHQKQMERAMLEN 325 >2EMT-A nrPDB Length = 322 Score = 592 bits (1526), Expect = e-169, Method: Compositional matrix adjust. Identities = 269/310 (86%), Positives = 300/310 (96%) Query: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLK 60 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKT+GLREVW+FGL YVD+KG+ TWLK Sbjct: 3 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLK 62 Query: 61 LDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPE 120 L+KKV+ Q+V+KENPLQFKFRAKF+PEDV+EELIQ+ITQ+LFFLQVKE IL+DEIYCPPE Sbjct: 63 LNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPE 122 Query: 121 TAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHR 180 TAVLL SYAVQAK+GDYNKE+HK GYL+++RL+PQRV++QHKLT++QWE+RIQ WH EHR Sbjct: 123 TAVLLASYAVQAKYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHR 182 Query: 181 GMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGF 240 GML++++M+EYLKIAQDLEMYG+NYFEIKNKKGT+LWLGVDALGLNIYE DDKLTPKIGF Sbjct: 183 GMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGF 242 Query: 241 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTI 300 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRIL LCMGNHELYMRRRKPDTI Sbjct: 243 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI 302 Query: 301 EVQQMKAQAR 310 EVQQMKAQAR Sbjct: 303 EVQQMKAQAR 312 >4YL8-A nrPDB Length = 303 Score = 557 bits (1435), Expect = e-159, Method: Compositional matrix adjust. Identities = 253/297 (85%), Positives = 284/297 (95%) Query: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLK 60 MPK I+VRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVW+FGL Y D K F TWLK Sbjct: 7 MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKAFSTWLK 66 Query: 61 LDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPE 120 L+KKV+AQ+VRKE+PL FKFRAKFYPEDV+EELIQDITQ+LFFLQVKEGIL+D+IYCPPE Sbjct: 67 LNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPE 126 Query: 121 TAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHR 180 TAVLL SYAVQ+K+GD+NKEVHKSGYL+ ++L+PQRV++QHKL +DQWE+RIQVWH EHR Sbjct: 127 TAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHR 186 Query: 181 GMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGF 240 GML+++A+LEYLKIAQDLEMYG+NYF IKNKKG++LWLGVDALGLNIYE++D+LTPKIGF Sbjct: 187 GMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGF 246 Query: 241 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKP 297 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRIL LCMGNHELYMRRRKP Sbjct: 247 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKP 303 >4ZRI-A nrPDB Length = 324 Score = 405 bits (1040), Expect = e-113, Method: Compositional matrix adjust. Identities = 186/303 (61%), Positives = 239/303 (78%), Gaps = 1/303 (0%) Query: 2 PKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKL 61 PK VR+ TMDAE+EF + GK LFD V +T+GLRE W+FGL Y K WLK+ Sbjct: 23 PKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYT-IKDTVAWLKM 81 Query: 62 DKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPET 121 DKKV +V KE P+ F F AKFYPE+ EEL+Q+ITQ LFFLQVK+ IL ++IYCPPE Sbjct: 82 DKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEA 141 Query: 122 AVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRG 181 +VLL SYAVQAK+GDY+ VHK G+L+ E L+P+RV++ +++T + WE+RI W+AEHRG Sbjct: 142 SVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRG 201 Query: 182 MLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFP 241 +D A +EYLKIAQDLEMYG+NYF I+NKKGT+L LGVDALGL+IY+ +++LTPKI FP Sbjct: 202 RARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFP 261 Query: 242 WSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIE 301 W+EIRNIS++DK+F IKP+DKK F F + +LR+NK ILQLC+GNH+L+MRRRK D++E Sbjct: 262 WNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLE 321 Query: 302 VQQ 304 VQQ Sbjct: 322 VQQ 324 >6IBE-A nrPDB Length = 286 Score = 143 bits (360), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 97/297 (32%), Positives = 151/297 (50%), Gaps = 21/297 (7%) Query: 1 MPKPINVRVTTMD-AELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWL 59 MPK + +V +D +E ++ + G+ LFD+V + + L E YFGL Y D + WL Sbjct: 2 MPKSMQCKVILLDGSEYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWL 61 Query: 60 KLDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPP 119 K++ Q + F F KFYP D A+ L +DIT+ LQ+++ I+S + C Sbjct: 62 DPAKEIKKQV--RSGAWHFSFNVKFYPPDPAQ-LSEDITRYYLCLQLRDDIVSGRLPCSF 118 Query: 120 ETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEH 179 T LLGSY VQ++ GDY+ + S Y+S R P + ED++ H H Sbjct: 119 VTLALLGSYTVQSELGDYDPDECGSDYISEFRFAPNHT--------KELEDKVIELHKSH 170 Query: 180 RGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIG 239 RGM A + +L+ A+ L MYG++ K+ +G ++ LGV A GL IY D+L +I Sbjct: 171 RGMTPAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYR--DRL--RIN 226 Query: 240 -FPWSEIRNISFNDKKFVIK----PIDKKAPDFVFYAPRLRINKRILQLCMGNHELY 291 F W ++ IS+ F IK ++ F P R KR+ ++C+ +H + Sbjct: 227 RFAWPKVLKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFF 283 >1GG3-A nrPDB Length = 279 Score = 141 bits (355), Expect = 8e-34, Method: Compositional matrix adjust. Identities = 95/296 (32%), Positives = 160/296 (54%), Gaps = 27/296 (9%) Query: 5 INVRVTTMDAEL-EFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKLDK 63 ++ +V+ +D + E ++ + G+ L +V + + L E YFGL DN TWL Sbjct: 1 MHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWLD--- 57 Query: 64 KVSAQEVRKEN---PLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPE 120 SA+E++K+ P F F KFYP D A+ L +DIT+ LQ+++ I++ + C Sbjct: 58 --SAKEIKKQVRGVPWNFTFNVKFYPPDPAQ-LTEDITRYYLCLQLRQDIVAGRLPCSFA 114 Query: 121 TAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHR 180 T LLGSY +Q++ GDY+ E+H Y+S +L P + + E+++ H +R Sbjct: 115 TLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT--------KELEEKVMELHKSYR 166 Query: 181 GMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIG- 239 M A LE+L+ A+ L MYG++ + K+ +G D+ LGV + GL +Y+ DKL +I Sbjct: 167 SMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYK--DKL--RINR 222 Query: 240 FPWSEIRNISFNDKKFVIK--PIDKKA--PDFVFYAPRLRINKRILQLCMGNHELY 291 FPW ++ IS+ F IK P +++ F P R K++ ++C+ +H + Sbjct: 223 FPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVCVEHHTFF 278 >6D2Q-A nrPDB Length = 285 Score = 127 bits (319), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 82/255 (32%), Positives = 137/255 (53%), Gaps = 16/255 (6%) Query: 5 INVRVTTMDAELE-FAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKLDK 63 I++RV +D E F + GK LFD V + L E YFGL + D + WL L K Sbjct: 5 ISIRVQMLDDTQEVFEVSQRAPGKALFDLVCSHLNLVEGDYFGLEFQDQRKMIVWLDLLK 64 Query: 64 KVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPETAV 123 + Q +R+ + +F KF+P D +L++++T+ LF LQ+K + + C +A Sbjct: 65 PILKQ-IRRPKNIILRFVVKFFPPD-HTQLLEELTRYLFALQIKHDLACGRLTCNESSAA 122 Query: 124 LLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRGML 183 LL ++ VQ++ GD++ EV +L + + IP++ D D+I +H +H G Sbjct: 123 LLVAHIVQSEIGDFD-EVQCKQHLLNNKYIPEQ---------DTLMDKIIGYHRKHVGQT 172 Query: 184 KDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFPWS 243 + + L+IA+ LEMYG+ K+++GT L L V G+ +++ K+ F WS Sbjct: 173 PAESDYQLLEIARRLEMYGVRLHPAKDREGTRLSLAVAHSGVLVFQGHTKIN---AFNWS 229 Query: 244 EIRNISFNDKKFVIK 258 ++R +SF K+F+IK Sbjct: 230 KVRKLSFKRKRFLIK 244 >1EF1-C nrPDB Length = 90 Score = 127 bits (318), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 61/87 (70%), Positives = 75/87 (86%) Query: 500 SAELSSEGIRDDRNEEKRITEAEKNERVQRQLLTLSSELSQARDENKRTHNDIIHNENMR 559 SA+L ++ + DR+EE+R TEAEKNERVQ+ L L+SEL+ ARDE+K+T ND+IH ENMR Sbjct: 4 SADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTANDMIHAENMR 63 Query: 560 QGRDKYKTLRQIRQGNTKQRIDEFEAL 586 GRDKYKTLRQIRQGNTKQRIDEFE++ Sbjct: 64 LGRDKYKTLRQIRQGNTKQRIDEFESM 90 >6D2K-A nrPDB Length = 288 Score = 120 bits (302), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 79/257 (30%), Positives = 140/257 (54%), Gaps = 16/257 (6%) Query: 3 KPINVRVTTMDAELE-FAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKL 61 K + +RV +D+ +E F I+P G+ L QV K + L E YFGL + + + + WL+ Sbjct: 6 KHMRIRVKLLDSTVELFDIEPKCDGQVLLTQVWKHLNLIECDYFGLEFKNVQSYWIWLEP 65 Query: 62 DKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPET 121 K + Q VRK + KF+P D + L ++ T+ LF LQ+K +L + + C T Sbjct: 66 MKPIIRQ-VRKPKNAVLRLAVKFFPPDPGQ-LQEEYTRYLFALQLKRDLLEERLTCTANT 123 Query: 122 AVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRG 181 A LL S+ +Q++ GDY++ + + +L + +P +++ ++I +H H G Sbjct: 124 AALLISHLLQSEIGDYDETLDRE-HLKANEYLPN---------QEKSLEKILDFHQRHTG 173 Query: 182 MLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFP 241 + + L+IA+ LEMYGI + +++GT + L V +G+ +++ K+ F Sbjct: 174 QTPAESDFQVLEIARKLEMYGIRFHMASDREGTKINLAVSHMGVLVFQGTTKINT---FN 230 Query: 242 WSEIRNISFNDKKFVIK 258 WS++R +SF K+F+IK Sbjct: 231 WSKVRKLSFKRKRFLIK 247 >6D21-A nrPDB Length = 333 Score = 120 bits (301), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 79/257 (30%), Positives = 133/257 (51%), Gaps = 16/257 (6%) Query: 3 KPINVRVTTMDAELEFA-IQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKL 61 K + +RV +D EF ++ G+ L V + I L E YFGL + + + WL Sbjct: 2 KGLQIRVQGLDEAQEFYELESKADGQLLLSDVFRRINLIESDYFGLEFQNLQMNWVWLDP 61 Query: 62 DKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPET 121 K + Q R N L F+ KF+P D + L ++ T+ LF LQ+K +L + C T Sbjct: 62 SKLIVKQVRRPMNTL-FRLSVKFFPPDPGQ-LQEEFTRYLFSLQIKRDLLDGRLSCTENT 119 Query: 122 AVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRG 181 A LL S+ VQ++ GDY+ ++ +L +L+P ++ +++I H H G Sbjct: 120 AALLASHLVQSEIGDYD-DLADREFLKMNKLLP---------CQEHVQEKIMELHRRHTG 169 Query: 182 MLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFP 241 + + L+IA+ LEM+G+ + +++GT + L V +GL +++ K+ F Sbjct: 170 QTPAESDFQVLEIARKLEMFGVRFHPAADREGTKINLAVAHMGLQVFQGHTKINT---FN 226 Query: 242 WSEIRNISFNDKKFVIK 258 WS+IR +SF K+F+IK Sbjct: 227 WSKIRKLSFKRKRFLIK 243 >2RQ1-A nrPDB Length = 109 Score = 67.4 bits (163), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 36/110 (32%), Positives = 61/110 (55%), Gaps = 8/110 (7%) Query: 92 ELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSER 151 +L +DIT+ LQ+++ I++ + C T LLGSY +Q++ GDY+ E+H Y+S + Sbjct: 8 QLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFK 67 Query: 152 LIPQRVMDQHKLTRDQWEDRIQVWHAEHRGMLKDNAMLEYLKIAQDLEMY 201 L P + + E+++ H +R M A LE+L+ A+ L MY Sbjct: 68 LAPNQT--------KELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMY 109 >3IVF-A nrPDB Length = 371 Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 38/154 (24%), Positives = 73/154 (47%), Gaps = 8/154 (5%) Query: 58 WLKLDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYC 117 WL + + Q V + L R KF+ D + + L ++Q ++ IL+ Sbjct: 144 WLDHGRTLREQGVEEHETLLL--RRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPV 201 Query: 118 PPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHA 177 + A + Q +FG +N++ HK+G+L + +P+ + Q + E +I H Sbjct: 202 SFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFLPKEYVKQ------KGERKIFQAHK 255 Query: 178 EHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNK 211 M + A + Y+K+A+ L+ YG+++F +K K Sbjct: 256 NCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEK 289 >1MK7-B nrPDB Length = 192 Score = 52.0 bits (123), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 30/111 (27%), Positives = 58/111 (52%), Gaps = 6/111 (5%) Query: 101 LFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQ 160 L ++Q ++ IL+ + A Y Q +FG +N++ HK G+L + +P+ + Q Sbjct: 6 LLYVQARDDILNGSHPVSFDKACEFAGYQCQIQFGPHNEQKHKPGFLELKDFLPKEYIKQ 65 Query: 161 HKLTRDQWEDRIQVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNK 211 + E +I + H M + A + Y+K+A+ L+ YG+++F +K K Sbjct: 66 ------KGERKIFMAHKNCGNMSEIEAKVRYVKLARSLKTYGVSFFLVKEK 110 >3G9W-A nrPDB Length = 223 Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 34/130 (26%), Positives = 61/130 (46%), Gaps = 5/130 (3%) Query: 82 AKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEV 141 KF+ D + + L ++Q ++ IL+ E A G + Q +FG + + Sbjct: 12 TKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHK 71 Query: 142 HKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRGMLKDNAMLEYLKIAQDLEMY 201 HK G+L + +P+ + Q E RI H M + A ++Y+K+A+ L Y Sbjct: 72 HKPGFLDLKEFLPKEYIKQRGA-----EKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTY 126 Query: 202 GINYFEIKNK 211 G+++F +K K Sbjct: 127 GVSFFLVKEK 136 >4F7G-A nrPDB Length = 222 Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 29/111 (26%), Positives = 58/111 (52%), Gaps = 6/111 (5%) Query: 101 LFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQ 160 L ++Q ++ IL+ + A + Q +FG +N++ HK+G+L + +P+ + Q Sbjct: 31 LLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFLPKEYVKQ 90 Query: 161 HKLTRDQWEDRIQVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNK 211 + E +I H M + A + Y+K+A+ L+ YG+++F +K K Sbjct: 91 ------KGERKIFQAHKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEK 135 >2HRJ-A nrPDB Length = 121 Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 31/122 (25%), Positives = 58/122 (47%), Gaps = 6/122 (4%) Query: 81 RAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDYNKE 140 R KF+ D + + L ++Q ++ IL+ + A Y Q +FG +N++ Sbjct: 6 RRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGYQCQIQFGPHNEQ 65 Query: 141 VHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRGMLKDNAMLEYLKIAQDLEM 200 HK G+L + +P+ + Q + E +I + H M + A + Y+K+A+ L+ Sbjct: 66 KHKPGFLELKDFLPKEYIKQ------KGERKIFMAHKNCGNMSEIEAKVRYVKLARSLKT 119 Query: 201 YG 202 YG Sbjct: 120 YG 121 >5MV9-A nrPDB Length = 527 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 39/151 (25%), Positives = 70/151 (46%), Gaps = 20/151 (13%) Query: 117 CPPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERL----IPQRVMDQHKLTRDQWEDRI 172 C E + LG+ + KF E KS + S +L +PQ ++ Q ++ D W+ I Sbjct: 341 CTREEVLQLGALIYRVKF-----EEDKSYFPSIPKLLRELVPQDLIRQ--VSPDDWKRSI 393 Query: 173 QVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTD----LWLGVDALGLNIY 228 + +H G K+ A L +LK+ +G +FE+K + L + ++ G+++ Sbjct: 394 VAYFNKHAGKSKEEAKLAFLKLIFKWPTFGSAFFEVKQTTEPNFPEILLIAINKYGVSLI 453 Query: 229 E--KDDKLTPKIGFPWSEIRNISFNDKKFVI 257 + D LT P+++I N S + F I Sbjct: 454 DPKTKDILTTH---PFTKISNWSSGNTYFHI 481 >5D68-A nrPDB Length = 486 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 49/230 (21%), Positives = 97/230 (42%), Gaps = 25/230 (10%) Query: 58 WLKLDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYC 117 W ++ +++ + ++E P F R P +V +++ + + F + + +L Sbjct: 237 WPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLLKGFYTA 296 Query: 118 PPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWH- 176 P + L S +Q +G+Y + HK G+L+ E L + + K W +RI H Sbjct: 297 PDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNRIL--HE 354 Query: 177 ----AEHRGMLKDNAMLE--YLKIAQDLEMYGINYF--------EIKNKKGTDLWLGVDA 222 + G+ K+ L+ +L+ ++ YG +F N K +++GV+ Sbjct: 355 YKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYVGVNI 414 Query: 223 LGLNIYEKDDK---LTPKIG-FPWSEIRNISFNDKKFVIKPIDKKAPDFV 268 GL++ + K ++ K G F W + D F I ++ K V Sbjct: 415 KGLHLLNMETKALLISLKYGCFMWQ----LGDTDTCFQIHSMENKMSFIV 460 >3PZD-A nrPDB Length = 511 Score = 39.7 bits (91), Expect = 0.004, Method: Compositional matrix adjust. Identities = 47/194 (24%), Positives = 83/194 (42%), Gaps = 30/194 (15%) Query: 60 KLDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLF-FLQVKEGILSDEIYCP 118 K +K + EV L +KF K Y + + +D + F F Q E ++ P Sbjct: 267 KFEKLAATSEV---GDLPWKFYFKLYCFLDTDNVPKDSVEFAFMFEQAHEAVIHGHHPAP 323 Query: 119 PETAVLLGSYAVQAKFGDYN--------KEVHKSGYLSSERLIPQRVMDQHKLTRDQW-- 168 E +L + +Q GDY +EV+ S +RL + D W Sbjct: 324 EENLQVLAALRLQYLQGDYTLHAAIPPLEEVY-----SLQRLKARISQSTKTQMLDMWIK 378 Query: 169 -------EDRIQVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGT---DLWL 218 I W + +GM ++ AM +Y+ + ++ YG F+++ K+G +LWL Sbjct: 379 EEVSSARASIIDKWR-KFQGMNQEQAMAKYMALIKEWPGYGSTLFDVECKEGGFPQELWL 437 Query: 219 GVDALGLNIYEKDD 232 GV A +++Y++ + Sbjct: 438 GVSADAVSVYKRGE 451 >4HDO-A nrPDB Length = 322 Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust. Identities = 44/204 (21%), Positives = 89/204 (43%), Gaps = 21/204 (10%) Query: 58 WLKLDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYC 117 W ++ +++ + ++E P F R P +V +++ + + F + + +L Sbjct: 73 WPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLLKGFYTA 132 Query: 118 PPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWH- 176 P + L S +Q +G+Y + HK G+L+ E L + + K W +RI H Sbjct: 133 PDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNRIL--HE 190 Query: 177 ----AEHRGMLKDNAMLE--YLKIAQDLEMYGINYF--------EIKNKKGTDLWLGVDA 222 + G+ K+ L+ +L+ ++ YG +F N K +++GV+ Sbjct: 191 YKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYVGVNI 250 Query: 223 LGLNIYEKDDK---LTPKIG-FPW 242 GL++ + K ++ K G F W Sbjct: 251 KGLHLLNMETKALLISLKYGCFMW 274 >4ZRJ-B nrPDB Length = 90 Score = 37.7 bits (86), Expect = 0.014, Method: Compositional matrix adjust. Identities = 24/74 (32%), Positives = 44/74 (59%), Gaps = 1/74 (1%) Query: 514 EEKRITEAEKNERVQRQLLTLSSELSQARDENKRTHNDIIHNENM-RQGRDKYKTLRQIR 572 E++++ EK++ +Q QL L +E+ + + + T DI+HNEN R G K+ T++++ Sbjct: 17 EKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKLT 76 Query: 573 QGNTKQRIDEFEAL 586 + K R+ FE L Sbjct: 77 LQSWKSRVAFFEEL 90 >3QR5-A nrPDB Length = 185 Score = 31.2 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 18/63 (28%), Positives = 30/63 (47%), Gaps = 1/63 (1%) Query: 392 DRMAALRAKEELERQAVDQI-KSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAK 450 D + LR +E+ Q I K Q++L + ++ LE K+ +VE+W+ K Sbjct: 12 DEIQFLRTDDEVVLQCTATIHKEQQKLCLAAEGFGNRLCFLESTSNSKQVDVEKWKFMMK 71 Query: 451 EAQ 453 AQ Sbjct: 72 TAQ 74 >3JAX-A nrPDB Length = 974 Score = 30.0 bits (66), Expect = 2.8, Method: Compositional matrix adjust. Identities = 21/71 (29%), Positives = 40/71 (56%), Gaps = 3/71 (4%) Query: 320 RQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEER 379 ++ LE + RR+ +E + +++EK +L L++Q ++ AE + I+ +QLE Sbjct: 871 KEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLE--- 927 Query: 380 KRAQEEAERLE 390 + +E ERLE Sbjct: 928 AKVKEMNERLE 938 >1YIO-A nrPDB Length = 208 Score = 29.3 bits (64), Expect = 5.0, Method: Compositional matrix adjust. Identities = 23/69 (33%), Positives = 40/69 (57%), Gaps = 3/69 (4%) Query: 362 ERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAEL 421 E+ L + I++ LQL ER++A+E ++LE ++L +E+ Q + +Q+A EL Sbjct: 109 EQALLDAIEQGLQLNAERRQARETQDQLE-QLFSSLTGREQQVLQLTIRGLMNKQIAGEL 167 Query: 422 --AEYTAKI 428 AE T K+ Sbjct: 168 GIAEVTVKV 176 >1ZXE-A nrPDB Length = 303 Score = 28.9 bits (63), Expect = 6.0, Method: Compositional matrix adjust. Identities = 14/26 (53%), Positives = 19/26 (73%), Gaps = 1/26 (3%) Query: 547 RTHNDIIHNENMRQGRDKY-KTLRQI 571 RT D+IH+EN+ Q RD+Y + RQI Sbjct: 100 RTLYDLIHSENLNQQRDEYWRLFRQI 125 >6C2V-A nrPDB Length = 115 Score = 28.5 bits (62), Expect = 8.0, Method: Composition-based stats. Identities = 15/38 (39%), Positives = 23/38 (60%) Query: 355 EEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEAD 392 +E +KA+ E+ + R + +E+ KR EEAER AD Sbjct: 19 DELARKAKEEVPDAEIRTVTTKEDAKRVAEEAERRNAD 56 >2NRA-C nrPDB Length = 276 Score = 28.5 bits (62), Expect = 8.2, Method: Compositional matrix adjust. Identities = 28/84 (33%), Positives = 45/84 (53%), Gaps = 6/84 (7%) Query: 386 AERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEW 445 A+R+ +A + +KE LER V +I++ E LAA LA+ T +A R+ KE Sbjct: 32 AKRVMYMALALIDSKEPLERGRVFKIRA-EDLAA-LAKITPSLAY----RQLKEGGKLLG 85 Query: 446 QHRAKEAQDDLVKTKEELHLVMTA 469 + DD++ +EL+L+ TA Sbjct: 86 ASKISLRGDDIIALAKELNLLSTA 109 >4ZPX-A nrPDB Length = 413 Score = 28.5 bits (62), Expect = 9.0, Method: Compositional matrix adjust. Identities = 24/77 (31%), Positives = 37/77 (48%), Gaps = 6/77 (7%) Query: 287 NHELYMRRRKPDTIEVQQMKAQ--AREEKHQKQLERQQLETEKKRRETVEREKEQMMREK 344 +E+YMR PDTIE ++ Q A+E K ++ K+ E + RE ++ K Sbjct: 316 GYEVYMRTTMPDTIENRRKLVQFVAQEVKRDGKIP----HFTKEAVEEIVREAQKRAGRK 371 Query: 345 EELMLRLQDYEEKTKKA 361 L LRL+D + A Sbjct: 372 GHLTLRLRDLGGIVRAA 388 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4RM9-A nrPDB 778 0.0 2I1J-A nrPDB 684 0.0 1E5W-A nrPDB 503 e-143 2EMT-A nrPDB 490 e-139 4YL8-A nrPDB 473 e-134 4RMA-A nrPDB 468 e-132 4ZRI-A nrPDB 426 e-119 6IBE-A nrPDB 371 e-103 1GG3-A nrPDB 356 2e-98 6D2Q-A nrPDB 320 1e-87 6D2K-A nrPDB 317 1e-86 6D21-A nrPDB 305 2e-83 3IVF-A nrPDB 193 2e-49 3G9W-A nrPDB 161 7e-40 2HRJ-A nrPDB 154 8e-38 4F7G-A nrPDB 153 1e-37 1MK7-B nrPDB 151 7e-37 2RQ1-A nrPDB 137 1e-32 1EF1-C nrPDB 108 7e-24 Sequences not found previously or not previously below threshold: 4HDO-A nrPDB 71 1e-12 5D68-A nrPDB 69 4e-12 5MV9-A nrPDB 64 2e-10 5EJS-A nrPDB 62 5e-10 5MV8-A nrPDB 62 7e-10 3PZD-A nrPDB 61 2e-09 5XQ1-A nrPDB 57 2e-08 2KMA-A nrPDB 50 3e-06 5XPY-A nrPDB 46 5e-05 3JCN-b nrPDB 40 0.003 5OFO-C nrPDB 39 0.004 1QVR-A nrPDB 39 0.005 6D00-1 nrPDB 39 0.006 6ED3-A nrPDB 39 0.006 6FYX-o nrPDB 38 0.009 5EW5-A nrPDB 38 0.010 3JAX-A nrPDB 38 0.011 1F5N-A nrPDB 38 0.011 3J3U-A nrPDB 38 0.013 2KC2-A nrPDB 37 0.015 3PXI-A nrPDB 37 0.019 4ZRJ-B nrPDB 37 0.022 3PXG-A nrPDB 37 0.024 5IJN-G nrPDB 37 0.026 4CIU-A nrPDB 36 0.035 3D2D-A nrPDB 36 0.035 2QAG-C nrPDB 36 0.056 4HSE-A nrPDB 36 0.064 3KYC-B nrPDB 35 0.082 5M6U-B nrPDB 34 0.13 5ZLU-EE nrPDB 34 0.14 3LJ5-A nrPDB 34 0.15 5Y5Z-N nrPDB 34 0.18 5FWP-E nrPDB 34 0.24 6BP7-A nrPDB 33 0.31 4TKO-B nrPDB 33 0.33 5KTG-A nrPDB 33 0.36 4Z4M-A nrPDB 33 0.36 4U2V-B nrPDB 33 0.36 4JRB-A nrPDB 33 0.36 3VHT-B nrPDB 33 0.36 4BDU-A nrPDB 33 0.41 4Z4K-A nrPDB 33 0.46 5OOL-q nrPDB 32 0.55 6GAZ-Ad nrPDB 32 0.56 5FGU-A nrPDB 32 0.65 3AI5-A nrPDB 32 0.66 3K2S-A nrPDB 32 0.68 5AMO-A nrPDB 32 0.69 1UUN-A nrPDB 32 0.70 3VHL-A nrPDB 32 0.71 4RSI-B nrPDB 32 0.72 5VY8-A nrPDB 32 0.78 5C8J-I nrPDB 32 0.84 3AI4-A nrPDB 31 1.1 3TBI-B nrPDB 31 1.1 4PZA-A nrPDB 31 1.2 5D4W-A nrPDB 31 1.3 2V71-A nrPDB 31 1.4 3KZ4-A nrPDB 31 1.5 1YIO-A nrPDB 31 1.5 3K1J-A nrPDB 31 1.6 6F1U-X nrPDB 31 1.6 3DWL-A nrPDB 31 1.6 4KV9-A nrPDB 31 1.8 5WLZ-C nrPDB 30 2.4 1ZXE-A nrPDB 30 2.5 6OJ5-A nrPDB 30 2.6 1YIR-A nrPDB 30 2.6 1SJJ-A nrPDB 30 2.6 6BJC-T nrPDB 30 2.8 4NBQ-A nrPDB 30 2.8 2TMA-A nrPDB 30 3.0 3S84-A nrPDB 30 3.0 3R2P-A nrPDB 30 3.2 3J9M-8 nrPDB 30 3.4 4DVY-P nrPDB 30 3.4 5AJ4-Ad nrPDB 30 3.6 3JCR-F nrPDB 30 3.8 5JCF-A nrPDB 30 3.9 4DVZ-A nrPDB 30 3.9 2NCA-A nrPDB 30 4.0 5WLC-LU nrPDB 29 4.5 5J1F-A nrPDB 29 4.5 5CWS-C nrPDB 29 4.5 5OQL-c nrPDB 29 4.7 5A1W-H nrPDB 29 5.3 4XY3-A nrPDB 29 5.4 6NEQ-d nrPDB 29 5.7 6HA8-V nrPDB 29 6.7 1PYS-A nrPDB 29 6.7 1UFA-A nrPDB 29 7.3 6FEC-u nrPDB 29 7.5 4L3I-A nrPDB 29 7.8 5O0Y-A nrPDB 29 7.9 5MDY-7 nrPDB 29 8.7 2EFK-A nrPDB 29 8.9 6FT6-s nrPDB 28 9.3 1BG7-A nrPDB 28 9.5 2DQ3-A nrPDB 28 9.7 >4RM9-A nrPDB Length = 587 Score = 778 bits (2009), Expect = 0.0, Method: Composition-based stats. Identities = 586/586 (100%), Positives = 586/586 (100%) Query: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLK 60 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLK Sbjct: 2 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLK 61 Query: 61 LDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPE 120 LDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPE Sbjct: 62 LDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPE 121 Query: 121 TAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHR 180 TAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHR Sbjct: 122 TAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHR 181 Query: 181 GMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGF 240 GMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGF Sbjct: 182 GMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGF 241 Query: 241 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTI 300 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTI Sbjct: 242 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTI 301 Query: 301 EVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKK 360 EVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKK Sbjct: 302 EVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKK 361 Query: 361 AERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAE 420 AERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAE Sbjct: 362 AERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAE 421 Query: 421 LAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEP 480 LAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEP Sbjct: 422 LAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEP 481 Query: 481 VSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQRQLLTLSSELSQ 540 VSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQRQLLTLSSELSQ Sbjct: 482 VSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQRQLLTLSSELSQ 541 Query: 541 ARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEAL 586 ARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEAL Sbjct: 542 ARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEAL 587 >2I1J-A nrPDB Length = 575 Score = 684 bits (1764), Expect = 0.0, Method: Composition-based stats. Identities = 340/602 (56%), Positives = 433/602 (71%), Gaps = 43/602 (7%) Query: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLK 60 MPK +NVRVTTMDAELEFAIQ TTGKQLFDQVVKTIGLREVW+FGL Y D+KG TW+K Sbjct: 1 MPKSMNVRVTTMDAELEFAIQQTTTGKQLFDQVVKTIGLREVWFFGLQYTDSKGDLTWIK 60 Query: 61 LDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPE 120 L KKV Q+V+KENPLQFKFRAKFYPEDVA+ELIQ+IT KLF+LQVK ILSDEIYCPPE Sbjct: 61 LYKKVMQQDVKKENPLQFKFRAKFYPEDVADELIQEITLKLFYLQVKNAILSDEIYCPPE 120 Query: 121 TAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHR 180 T+VLL SYAVQA+ GD+N VH G+L+++RL+PQRV DQHK++R++WE I W EHR Sbjct: 121 TSVLLASYAVQARHGDHNPAVHGPGFLANDRLLPQRVTDQHKMSREEWEQSITNWWQEHR 180 Query: 181 GMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGF 240 GML+++AM+EYLKIAQDLEMYG+NYFEI+NKK T+LWLGVDALGLNIYEKDDKLTPKIGF Sbjct: 181 GMLREDAMMEYLKIAQDLEMYGVNYFEIRNKKNTELWLGVDALGLNIYEKDDKLTPKIGF 240 Query: 241 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTI 300 PWSEIRNISFND+KF+IKPIDKKAPDFVF+APR+R+NKRIL LCMGNHELYMRRRKPDTI Sbjct: 241 PWSEIRNISFNDRKFIIKPIDKKAPDFVFFAPRVRVNKRILALCMGNHELYMRRRKPDTI 300 Query: 301 EVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKK 360 +VQQMKAQAREEK KQ +R++L+ E RE E ++++E RL+ +E+ ++ Sbjct: 301 DVQQMKAQAREEKLAKQAQREKLQLEIAARERAE-------KKQQEYQDRLRQMQEEMER 353 Query: 361 AERELSEQIQRALQLEEERKRAQEEAERLE---------ADRMAALRAKEELERQAV-DQ 410 ++ L E L+LEE+ ++ Q E LE R+ + E ERQ + D+ Sbjct: 354 SQANLLEAQDMILRLEEQLRQLQAAKEELEQRQNELQAMMQRLEETKNMEAAERQKLEDE 413 Query: 411 IKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVK------TKEELH 464 I+++++ E++ ++ L + RR ++EVE+ A+ QD+ T + H Sbjct: 414 IRAKQE---EVSRIQQEVELKDSETRRLQEEVED----ARRKQDEAAAALLAATTPQHHH 466 Query: 465 LVMTAPPPPPPPVYEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKN 524 + A P ++ D G+E G + + D + R T AE+N Sbjct: 467 VAERADTDPD-----------HDNASDAGSESGGGDLARGPDDLVDPVAD--RRTLAERN 513 Query: 525 ERVQRQLLTLSSELSQARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFE 584 ER+ QL L +L+++ DE K T D IH EN+RQGRDKYKTLR+IR+GNTK+R+D+FE Sbjct: 514 ERLHNQLKALKQDLARSCDETKETAMDKIHRENVRQGRDKYKTLREIRKGNTKRRVDQFE 573 Query: 585 AL 586 + Sbjct: 574 NM 575 >1E5W-A nrPDB Length = 346 Score = 503 bits (1295), Expect = e-143, Method: Composition-based stats. Identities = 278/325 (85%), Positives = 310/325 (95%) Query: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLK 60 MPK I+VRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVW+FGL Y D KGF TWLK Sbjct: 1 MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLK 60 Query: 61 LDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPE 120 L+KKV+AQ+VRKE+PL FKFRAKFYPEDV+EELIQDITQ+LFFLQVKEGIL+D+IYCPPE Sbjct: 61 LNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPE 120 Query: 121 TAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHR 180 TAVLL SYAVQ+K+GD+NKEVHKSGYL+ ++L+PQRV++QHKL +DQWE+RIQVWH EHR Sbjct: 121 TAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHR 180 Query: 181 GMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGF 240 GML+++A+LEYLKIAQDLEMYG+NYF IKNKKG++LWLGVDALGLNIYE++D+LTPKIGF Sbjct: 181 GMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGF 240 Query: 241 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTI 300 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRIL LCMGNHELYMRRRKPDTI Sbjct: 241 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI 300 Query: 301 EVQQMKAQAREEKHQKQLERQQLET 325 EVQQMKAQAREEKHQKQ+ER LE Sbjct: 301 EVQQMKAQAREEKHQKQMERAMLEN 325 >2EMT-A nrPDB Length = 322 Score = 490 bits (1260), Expect = e-139, Method: Composition-based stats. Identities = 269/310 (86%), Positives = 300/310 (96%) Query: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLK 60 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKT+GLREVW+FGL YVD+KG+ TWLK Sbjct: 3 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLK 62 Query: 61 LDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPE 120 L+KKV+ Q+V+KENPLQFKFRAKF+PEDV+EELIQ+ITQ+LFFLQVKE IL+DEIYCPPE Sbjct: 63 LNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPE 122 Query: 121 TAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHR 180 TAVLL SYAVQAK+GDYNKE+HK GYL+++RL+PQRV++QHKLT++QWE+RIQ WH EHR Sbjct: 123 TAVLLASYAVQAKYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHR 182 Query: 181 GMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGF 240 GML++++M+EYLKIAQDLEMYG+NYFEIKNKKGT+LWLGVDALGLNIYE DDKLTPKIGF Sbjct: 183 GMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGF 242 Query: 241 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTI 300 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRIL LCMGNHELYMRRRKPDTI Sbjct: 243 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI 302 Query: 301 EVQQMKAQAR 310 EVQQMKAQAR Sbjct: 303 EVQQMKAQAR 312 >4YL8-A nrPDB Length = 303 Score = 473 bits (1218), Expect = e-134, Method: Composition-based stats. Identities = 253/297 (85%), Positives = 284/297 (95%) Query: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLK 60 MPK I+VRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVW+FGL Y D K F TWLK Sbjct: 7 MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKAFSTWLK 66 Query: 61 LDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPE 120 L+KKV+AQ+VRKE+PL FKFRAKFYPEDV+EELIQDITQ+LFFLQVKEGIL+D+IYCPPE Sbjct: 67 LNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPE 126 Query: 121 TAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHR 180 TAVLL SYAVQ+K+GD+NKEVHKSGYL+ ++L+PQRV++QHKL +DQWE+RIQVWH EHR Sbjct: 127 TAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHR 186 Query: 181 GMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGF 240 GML+++A+LEYLKIAQDLEMYG+NYF IKNKKG++LWLGVDALGLNIYE++D+LTPKIGF Sbjct: 187 GMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGF 246 Query: 241 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKP 297 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRIL LCMGNHELYMRRRKP Sbjct: 247 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKP 303 >4RMA-A nrPDB Length = 296 Score = 468 bits (1204), Expect = e-132, Method: Composition-based stats. Identities = 296/296 (100%), Positives = 296/296 (100%) Query: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLK 60 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLK Sbjct: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLK 60 Query: 61 LDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPE 120 LDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPE Sbjct: 61 LDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPE 120 Query: 121 TAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHR 180 TAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHR Sbjct: 121 TAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHR 180 Query: 181 GMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGF 240 GMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGF Sbjct: 181 GMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGF 240 Query: 241 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRK 296 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRK Sbjct: 241 PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRK 296 >4ZRI-A nrPDB Length = 324 Score = 426 bits (1094), Expect = e-119, Method: Composition-based stats. Identities = 186/303 (61%), Positives = 239/303 (78%), Gaps = 1/303 (0%) Query: 2 PKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKL 61 PK VR+ TMDAE+EF + GK LFD V +T+GLRE W+FGL Y K WLK+ Sbjct: 23 PKTFTVRIVTMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYT-IKDTVAWLKM 81 Query: 62 DKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPET 121 DKKV +V KE P+ F F AKFYPE+ EEL+Q+ITQ LFFLQVK+ IL ++IYCPPE Sbjct: 82 DKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPPEA 141 Query: 122 AVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRG 181 +VLL SYAVQAK+GDY+ VHK G+L+ E L+P+RV++ +++T + WE+RI W+AEHRG Sbjct: 142 SVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRG 201 Query: 182 MLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFP 241 +D A +EYLKIAQDLEMYG+NYF I+NKKGT+L LGVDALGL+IY+ +++LTPKI FP Sbjct: 202 RARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFP 261 Query: 242 WSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIE 301 W+EIRNIS++DK+F IKP+DKK F F + +LR+NK ILQLC+GNH+L+MRRRK D++E Sbjct: 262 WNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLE 321 Query: 302 VQQ 304 VQQ Sbjct: 322 VQQ 324 >6IBE-A nrPDB Length = 286 Score = 371 bits (953), Expect = e-103, Method: Composition-based stats. Identities = 94/296 (31%), Positives = 148/296 (50%), Gaps = 19/296 (6%) Query: 1 MPKPINVRVTTMD-AELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWL 59 MPK + +V +D +E ++ + G+ LFD+V + + L E YFGL Y D + WL Sbjct: 2 MPKSMQCKVILLDGSEYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWL 61 Query: 60 KLDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPP 119 K++ Q + F F KFYP D A+ L +DIT+ LQ+++ I+S + C Sbjct: 62 DPAKEIKKQV--RSGAWHFSFNVKFYPPDPAQ-LSEDITRYYLCLQLRDDIVSGRLPCSF 118 Query: 120 ETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEH 179 T LLGSY VQ++ GDY+ + S Y+S R P + ED++ H H Sbjct: 119 VTLALLGSYTVQSELGDYDPDECGSDYISEFRFAPNHT--------KELEDKVIELHKSH 170 Query: 180 RGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIG 239 RGM A + +L+ A+ L MYG++ K+ +G ++ LGV A GL IY ++ Sbjct: 171 RGMTPAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRLRIN---R 227 Query: 240 FPWSEIRNISFNDKKFVIK----PIDKKAPDFVFYAPRLRINKRILQLCMGNHELY 291 F W ++ IS+ F IK ++ F P R KR+ ++C+ +H + Sbjct: 228 FAWPKVLKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFF 283 >1GG3-A nrPDB Length = 279 Score = 356 bits (913), Expect = 2e-98, Method: Composition-based stats. Identities = 89/292 (30%), Positives = 153/292 (52%), Gaps = 19/292 (6%) Query: 5 INVRVTTMDAE-LEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKLDK 63 ++ +V+ +D E ++ + G+ L +V + + L E YFGL DN TWL K Sbjct: 1 MHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWLDSAK 60 Query: 64 KVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPETAV 123 ++ Q + P F F KFYP D A+ L +DIT+ LQ+++ I++ + C T Sbjct: 61 EIKKQV--RGVPWNFTFNVKFYPPDPAQ-LTEDITRYYLCLQLRQDIVAGRLPCSFATLA 117 Query: 124 LLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRGML 183 LLGSY +Q++ GDY+ E+H Y+S +L P + + E+++ H +R M Sbjct: 118 LLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT--------KELEEKVMELHKSYRSMT 169 Query: 184 KDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFPWS 243 A LE+L+ A+ L MYG++ + K+ +G D+ LGV + GL +Y+ ++ FPW Sbjct: 170 PAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRIN---RFPWP 226 Query: 244 EIRNISFNDKKFVIK--PIDKKA--PDFVFYAPRLRINKRILQLCMGNHELY 291 ++ IS+ F IK P +++ F P R K++ ++C+ +H + Sbjct: 227 KVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVCVEHHTFF 278 >6D2Q-A nrPDB Length = 285 Score = 320 bits (819), Expect = 1e-87, Method: Composition-based stats. Identities = 86/294 (29%), Positives = 146/294 (49%), Gaps = 20/294 (6%) Query: 3 KPINVRVTTMDAELE-FAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKL 61 + I++RV +D E F + GK LFD V + L E YFGL + D + WL L Sbjct: 3 RQISIRVQMLDDTQEVFEVSQRAPGKALFDLVCSHLNLVEGDYFGLEFQDQRKMIVWLDL 62 Query: 62 DKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPET 121 K + Q +R+ + +F KF+P D +L++++T+ LF LQ+K + + C + Sbjct: 63 LKPILKQ-IRRPKNIILRFVVKFFPPD-HTQLLEELTRYLFALQIKHDLACGRLTCNESS 120 Query: 122 AVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRG 181 A LL ++ VQ++ GD++ EV +L + + IP++ D D+I +H +H G Sbjct: 121 AALLVAHIVQSEIGDFD-EVQCKQHLLNNKYIPEQ---------DTLMDKIIGYHRKHVG 170 Query: 182 MLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFP 241 + + L+IA+ LEMYG+ K+++GT L L V G+ +++ K+ F Sbjct: 171 QTPAESDYQLLEIARRLEMYGVRLHPAKDREGTRLSLAVAHSGVLVFQGHTKIN---AFN 227 Query: 242 WSEIRNISFNDKKFVIK----PIDKKAPDFVFYAPRLRINKRILQLCMGNHELY 291 WS++R +SF K+F+IK F K ++C+ H + Sbjct: 228 WSKVRKLSFKRKRFLIKLRPDLNSNCQDTLEFMMGSRDCCKVFWKICVEYHAFF 281 >6D2K-A nrPDB Length = 288 Score = 317 bits (811), Expect = 1e-86, Method: Composition-based stats. Identities = 83/294 (28%), Positives = 149/294 (50%), Gaps = 20/294 (6%) Query: 3 KPINVRVTTMDAELE-FAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKL 61 K + +RV +D+ +E F I+P G+ L QV K + L E YFGL + + + + WL+ Sbjct: 6 KHMRIRVKLLDSTVELFDIEPKCDGQVLLTQVWKHLNLIECDYFGLEFKNVQSYWIWLEP 65 Query: 62 DKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPET 121 K + Q VRK + KF+P D + L ++ T+ LF LQ+K +L + + C T Sbjct: 66 MKPIIRQ-VRKPKNAVLRLAVKFFPPDPGQ-LQEEYTRYLFALQLKRDLLEERLTCTANT 123 Query: 122 AVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRG 181 A LL S+ +Q++ GDY++ + + +L + +P + ++ ++I +H H G Sbjct: 124 AALLISHLLQSEIGDYDETLDR-EHLKANEYLPNQ---------EKSLEKILDFHQRHTG 173 Query: 182 MLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFP 241 + + L+IA+ LEMYGI + +++GT + L V +G+ +++ K+ F Sbjct: 174 QTPAESDFQVLEIARKLEMYGIRFHMASDREGTKINLAVSHMGVLVFQGTTKINT---FN 230 Query: 242 WSEIRNISFNDKKFVIKPIDK----KAPDFVFYAPRLRINKRILQLCMGNHELY 291 WS++R +SF K+F+IK + F K ++C+ H + Sbjct: 231 WSKVRKLSFKRKRFLIKLHPEVHGPYQDTLEFLLGSRDECKNFWKICVEYHTFF 284 >6D21-A nrPDB Length = 333 Score = 305 bits (782), Expect = 2e-83, Method: Composition-based stats. Identities = 86/327 (26%), Positives = 154/327 (47%), Gaps = 20/327 (6%) Query: 3 KPINVRVTTMDAELEFA-IQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKL 61 K + +RV +D EF ++ G+ L V + I L E YFGL + + + WL Sbjct: 2 KGLQIRVQGLDEAQEFYELESKADGQLLLSDVFRRINLIESDYFGLEFQNLQMNWVWLDP 61 Query: 62 DKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPET 121 K + Q R N L F+ KF+P D + L ++ T+ LF LQ+K +L + C T Sbjct: 62 SKLIVKQVRRPMNTL-FRLSVKFFPPDPGQ-LQEEFTRYLFSLQIKRDLLDGRLSCTENT 119 Query: 122 AVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRG 181 A LL S+ VQ++ GDY+ ++ +L +L+P ++ +++I H H G Sbjct: 120 AALLASHLVQSEIGDYD-DLADREFLKMNKLLP---------CQEHVQEKIMELHRRHTG 169 Query: 182 MLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFP 241 + + L+IA+ LEM+G+ + +++GT + L V +GL +++ K+ F Sbjct: 170 QTPAESDFQVLEIARKLEMFGVRFHPAADREGTKINLAVAHMGLQVFQGHTKINT---FN 226 Query: 242 WSEIRNISFNDKKFVIKPIDK----KAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKP 297 WS+IR +SF K+F+IK + F K + C+ +H + +P Sbjct: 227 WSKIRKLSFKRKRFLIKLHPEVHGPHQDTLEFLMGSRDQCKIFWKNCVEHHSFFRLLDQP 286 Query: 298 DTIEVQQMKAQAREEKHQKQLERQQLE 324 ++ ++ + ++Q +E Sbjct: 287 QPKSKAIFFSRGSSFRYSGRTQKQLVE 313 >3IVF-A nrPDB Length = 371 Score = 193 bits (491), Expect = 2e-49, Method: Composition-based stats. Identities = 45/214 (21%), Positives = 93/214 (43%), Gaps = 13/214 (6%) Query: 3 KPINVRVTTMDAEL-EFAIQPNTTGKQLFDQVVKTIGLREVWYFGL--HYVDNKGF--PT 57 K +++ +D + + + T + + IG+ + L ++ K Sbjct: 84 KQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICARIGITNHDEYSLVRELMEEKKDDELN 143 Query: 58 WLKLDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYC 117 WL + + Q V + L R KF+ D + + L ++Q ++ IL+ Sbjct: 144 WLDHGRTLREQGVEEHETLLL--RRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPV 201 Query: 118 PPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHA 177 + A + Q +FG +N++ HK+G+L + +P+ + Q + E +I H Sbjct: 202 SFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFLPKEYVKQ------KGERKIFQAHK 255 Query: 178 EHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNK 211 M + A + Y+K+A+ L+ YG+++F +K K Sbjct: 256 NCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEK 289 >3G9W-A nrPDB Length = 223 Score = 161 bits (408), Expect = 7e-40, Method: Composition-based stats. Identities = 46/220 (20%), Positives = 98/220 (44%), Gaps = 14/220 (6%) Query: 82 AKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEV 141 KF+ D + + L ++Q ++ IL+ E A G + Q +FG + + Sbjct: 12 TKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHK 71 Query: 142 HKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRGMLKDNAMLEYLKIAQDLEMY 201 HK G+L + +P+ + Q E RI H M + A ++Y+K+A+ L Y Sbjct: 72 HKPGFLDLKEFLPKEYIKQRGA-----EKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTY 126 Query: 202 GINYFEIKNK-----KGTDLWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDKKFV 256 G+++F +K K K LG+ + ++ K +P + ++ + + K F Sbjct: 127 GVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTK-EVLQEWPLTTVKRWAASPKSFT 185 Query: 257 IKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRK 296 + + + +Y+ + ++I QL G ++ +++++ Sbjct: 186 LDFGEYQES---YYSVQTTEGEQISQLIAGYIDIILKKKQ 222 >2HRJ-A nrPDB Length = 121 Score = 154 bits (390), Expect = 8e-38, Method: Composition-based stats. Identities = 31/126 (24%), Positives = 58/126 (46%), Gaps = 6/126 (4%) Query: 77 QFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGD 136 R KF+ D + + L ++Q ++ IL+ + A Y Q +FG Sbjct: 2 TLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGYQCQIQFGP 61 Query: 137 YNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRGMLKDNAMLEYLKIAQ 196 +N++ HK G+L + +P+ + Q + E +I + H M + A + Y+K+A+ Sbjct: 62 HNEQKHKPGFLELKDFLPKEYIKQ------KGERKIFMAHKNCGNMSEIEAKVRYVKLAR 115 Query: 197 DLEMYG 202 L+ YG Sbjct: 116 SLKTYG 121 >4F7G-A nrPDB Length = 222 Score = 153 bits (387), Expect = 1e-37, Method: Composition-based stats. Identities = 47/211 (22%), Positives = 97/211 (45%), Gaps = 15/211 (7%) Query: 91 EELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSE 150 + + L ++Q ++ IL+ + A + Q +FG +N++ HK+G+L + Sbjct: 21 QSSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLK 80 Query: 151 RLIPQRVMDQHKLTRDQWEDRIQVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKN 210 +P+ + Q + E +I H M + A + Y+K+A+ L+ YG+++F +K Sbjct: 81 DFLPKEYVKQ------KGERKIFQAHKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKE 134 Query: 211 KKGTDLWLGVDALGLN---IYEKDDKLTPKIGFPWS--EIRNISFNDKKFVIKPIDKKAP 265 K L LG+ + D+K I WS I+ + + K F + D + Sbjct: 135 KMKGKNKLVPRLLGITKECVMRVDEKTKEVIQ-EWSLTNIKRWAASPKSFTLDFGDYQD- 192 Query: 266 DFVFYAPRLRINKRILQLCMGNHELYMRRRK 296 +Y+ + ++I QL G ++ ++++K Sbjct: 193 --GYYSVQTTEGEQIAQLIAGYIDIILKKKK 221 >1MK7-B nrPDB Length = 192 Score = 151 bits (382), Expect = 7e-37, Method: Composition-based stats. Identities = 30/116 (25%), Positives = 59/116 (50%), Gaps = 6/116 (5%) Query: 96 DITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQ 155 + L ++Q ++ IL+ + A Y Q +FG +N++ HK G+L + +P+ Sbjct: 1 PVQLNLLYVQARDDILNGSHPVSFDKACEFAGYQCQIQFGPHNEQKHKPGFLELKDFLPK 60 Query: 156 RVMDQHKLTRDQWEDRIQVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNK 211 + Q + E +I + H M + A + Y+K+A+ L+ YG+++F +K K Sbjct: 61 EYIKQ------KGERKIFMAHKNCGNMSEIEAKVRYVKLARSLKTYGVSFFLVKEK 110 >2RQ1-A nrPDB Length = 109 Score = 137 bits (346), Expect = 1e-32, Method: Composition-based stats. Identities = 38/114 (33%), Positives = 63/114 (55%), Gaps = 9/114 (7%) Query: 88 DVAEELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEVHKSGYL 147 D A+ L +DIT+ LQ+++ I++ + C T LLGSY +Q++ GDY+ E+H Y+ Sbjct: 5 DPAQ-LTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYV 63 Query: 148 SSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRGMLKDNAMLEYLKIAQDLEMY 201 S +L P + + E+++ H +R M A LE+L+ A+ L MY Sbjct: 64 SDFKLAPNQT--------KELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMY 109 >1EF1-C nrPDB Length = 90 Score = 108 bits (269), Expect = 7e-24, Method: Composition-based stats. Identities = 61/87 (70%), Positives = 75/87 (86%) Query: 500 SAELSSEGIRDDRNEEKRITEAEKNERVQRQLLTLSSELSQARDENKRTHNDIIHNENMR 559 SA+L ++ + DR+EE+R TEAEKNERVQ+ L L+SEL+ ARDE+K+T ND+IH ENMR Sbjct: 4 SADLRADAMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTANDMIHAENMR 63 Query: 560 QGRDKYKTLRQIRQGNTKQRIDEFEAL 586 GRDKYKTLRQIRQGNTKQRIDEFE++ Sbjct: 64 LGRDKYKTLRQIRQGNTKQRIDEFESM 90 >4HDO-A nrPDB Length = 322 Score = 71.0 bits (172), Expect = 1e-12, Method: Composition-based stats. Identities = 47/243 (19%), Positives = 98/243 (40%), Gaps = 21/243 (8%) Query: 58 WLKLDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYC 117 W ++ +++ + ++E P F R P +V +++ + + F + + +L Sbjct: 73 WPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLLKGFYTA 132 Query: 118 PPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHA 177 P + L S +Q +G+Y + HK G+L+ E L + + K W +RI + Sbjct: 133 PDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNRILHEYK 192 Query: 178 EHRGMLKDNAMLE-----YLKIAQDLEMYGINYF--------EIKNKKGTDLWLGVDALG 224 + + +L+ ++ YG +F N K +++GV+ G Sbjct: 193 NLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYVGVNIKG 252 Query: 225 LNIYEKDDK---LTPKIG-FPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRI 280 L++ + K ++ K G F W + D F I ++ K V + K + Sbjct: 253 LHLLNMETKALLISLKYGCFMW----QLGDTDTCFQIHSMENKMSFIVHTKQAGLVVKLL 308 Query: 281 LQL 283 ++L Sbjct: 309 MKL 311 >5D68-A nrPDB Length = 486 Score = 69.4 bits (168), Expect = 4e-12, Method: Composition-based stats. Identities = 47/243 (19%), Positives = 98/243 (40%), Gaps = 21/243 (8%) Query: 58 WLKLDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYC 117 W ++ +++ + ++E P F R P +V +++ + + F + + +L Sbjct: 237 WPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLLKGFYTA 296 Query: 118 PPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHA 177 P + L S +Q +G+Y + HK G+L+ E L + + K W +RI + Sbjct: 297 PDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNRILHEYK 356 Query: 178 EHRGMLKDNAMLE-----YLKIAQDLEMYGINYF--------EIKNKKGTDLWLGVDALG 224 + + +L+ ++ YG +F N K +++GV+ G Sbjct: 357 NLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYVGVNIKG 416 Query: 225 LNIYEKDDK---LTPKIG-FPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRI 280 L++ + K ++ K G F W + D F I ++ K V + K + Sbjct: 417 LHLLNMETKALLISLKYGCFMW----QLGDTDTCFQIHSMENKMSFIVHTKQAGLVVKLL 472 Query: 281 LQL 283 ++L Sbjct: 473 MKL 475 >5MV9-A nrPDB Length = 527 Score = 63.6 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 49/245 (20%), Positives = 97/245 (39%), Gaps = 22/245 (8%) Query: 22 PNTTGKQLFDQVV-KTIGLREVWYFGLHYVDNKGFPTWLKLDKKVSAQEVRKENPLQFKF 80 ++ G LF ++ K + + E +F + + W+K + + + Q F Sbjct: 250 KSSEGFSLFVKIADKVLSVPENDFF---FDFVRHLTDWIKKARPIKD-GIVPSLTYQVFF 305 Query: 81 RAKFYPEDVAEELIQDITQKLF-FLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGD--- 136 K + + +F + Q L C E + LG+ + KF + Sbjct: 306 MKKLW--TTTVPGKDPMADSIFHYYQELPKYLRGYHKCTREEVLQLGALIYRVKFEEDKS 363 Query: 137 YNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRGMLKDNAMLEYLKIAQ 196 Y + K L+PQ ++ Q ++ D W+ I + +H G K+ A L +LK+ Sbjct: 364 YFPSIPK----LLRELVPQDLIRQ--VSPDDWKRSIVAYFNKHAGKSKEEAKLAFLKLIF 417 Query: 197 DLEMYGINYFEIKNKKGTD----LWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFND 252 +G +FE+K + L + ++ G+++ + K P+++I N S + Sbjct: 418 KWPTFGSAFFEVKQTTEPNFPEILLIAINKYGVSLIDPKTK-DILTTHPFTKISNWSSGN 476 Query: 253 KKFVI 257 F I Sbjct: 477 TYFHI 481 >5EJS-A nrPDB Length = 496 Score = 62.5 bits (150), Expect = 5e-10, Method: Composition-based stats. Identities = 58/305 (19%), Positives = 126/305 (41%), Gaps = 43/305 (14%) Query: 6 NVRVTTMDAELEFA-IQPNTTGKQLFDQVVKTIGLRE--VWYFGLHYVD----NKGFPTW 58 ++ +D + A I TT +++ D V + G+ + + FG+ V+ + Sbjct: 197 TCKIRFIDQSTKLAKINTYTTIREITDTVCRQYGISQQSIKMFGISAVNETAGISKVVSE 256 Query: 59 LKLDKKVSAQEVRKENPLQFKF--RAKFYPEDVAEELIQ-------DITQKLFFLQVKEG 109 + V A+ + E +F F R +F+ +DV + L Q DI +L + Q+++ Sbjct: 257 TDMIYDVLARWEQSEEKGEFYFQVRRRFFLDDVNKILDQEHLWTDDDICFELTYCQIRDE 316 Query: 110 ILSDEIY-CPPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQH--KLTRD 166 + + + ++ + +Q + + +K V + +++P ++++ K+ Sbjct: 317 WMKGLYTNVNEKDSSIIAAILIQLLYPNQSKLVLTKEVV--RQVLPDQILNSQNIKVWIS 374 Query: 167 QWEDRIQVWHAEHRGMLKDNAMLEYLK-IAQDLEMYGINYFEIKNKKGT-DLWLGVDALG 224 E +I + L ++ I ++G F I+ K+ WL ++ G Sbjct: 375 MIESQIFEL----VSQTPEYLKLMFINLIGSKSPLFGCTLFNIQQKENPPKAWLAINKKG 430 Query: 225 LNIYEKDDKLTPKIGFPWSEIRNISFNDKKFVI------KPIDKK---------APDFVF 269 ++I++ K K + + I N++F D F I KPI + A + F Sbjct: 431 VSIFDPHTK-ESKNFWTFQSISNVAFTDDTFCIMTGNLMKPIKQTFTTDEHSSIASVYQF 489 Query: 270 YAPRL 274 Y+ +L Sbjct: 490 YSSQL 494 >5MV8-A nrPDB Length = 527 Score = 62.1 bits (149), Expect = 7e-10, Method: Composition-based stats. Identities = 40/232 (17%), Positives = 90/232 (38%), Gaps = 16/232 (6%) Query: 24 TTGKQLFDQVV-KTIGLREVWYFGLHYVDNKGFPTWLKLDKKVSAQEVRKENPLQFKFRA 82 G LF ++ K I +E +F + + W+K +K + P Q F Sbjct: 248 WEGCSLFIKISDKVISQKEGDFF---FDSLREVSDWVKKNKP-QKEGAPVTLPYQVYFMR 303 Query: 83 KFYPE-DVAEELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEV 141 K + +++ D + Q L C E A+ L +A+F + ++ Sbjct: 304 KLWLNISPGKDVNADTILH--YHQELPKYLRGFHKCSREDAIHLAGLIYKAQFNNDRSQL 361 Query: 142 HKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRGMLKDNAMLEYLKIAQDLEMY 201 + L+P+ + ++ ++W+ I + + +H+ + A + +LK + Sbjct: 362 ASVPKI-LRELVPENLTRL--MSSEEWKKSILLAYDKHKDKTVEEAKVAFLKWICRWPTF 418 Query: 202 GINYFEIKNKKGTD----LWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNIS 249 G +FE+K + + ++ G+ + K +P+++I + S Sbjct: 419 GSAFFEVKQTSEPSYPDVILIAINRHGVLLIHPKTK-DLLTTYPFTKISSWS 469 >3PZD-A nrPDB Length = 511 Score = 60.6 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 37/169 (21%), Positives = 66/169 (39%), Gaps = 15/169 (8%) Query: 75 PLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKF 134 P +F F+ + D + F Q E ++ P E +L + +Q Sbjct: 281 PWKFYFKLYCFL-DTDNVPKDSVEFAFMFEQAHEAVIHGHHPAPEENLQVLAALRLQYLQ 339 Query: 135 GDYNKEVHKS---GYLSSERLIPQRVMDQHKLTRDQWEDR--------IQVWHAEHRGML 183 GDY S +RL + D W I + +GM Sbjct: 340 GDYTLHAAIPPLEEVYSLQRLKARISQSTKTQMLDMWIKEEVSSARASIIDKWRKFQGMN 399 Query: 184 KDNAMLEYLKIAQDLEMYGINYFEIKNKKG---TDLWLGVDALGLNIYE 229 ++ AM +Y+ + ++ YG F+++ K+G +LWLGV A +++Y+ Sbjct: 400 QEQAMAKYMALIKEWPGYGSTLFDVECKEGGFPQELWLGVSADAVSVYK 448 >5XQ1-A nrPDB Length = 485 Score = 57.1 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 35/166 (21%), Positives = 66/166 (39%), Gaps = 7/166 (4%) Query: 52 NKGFPTWLKLDKKVSAQEVRKENPLQFKFRA-KFYPEDVAEELIQDITQKLFFLQVKEGI 110 K WL + + Q+V++ L +F+ F+ + + I + Q K + Sbjct: 200 AKTNQGWLDSSRSLMEQDVKENEALLLRFKYYSFFDLNPKYDA---IRINQLYEQAKWAL 256 Query: 111 LSDEIYCPPETAVLLGSYAVQA-KFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWE 169 L +EI C E ++ + K E H + ++ E L+ R + ++K Q Sbjct: 257 LLEEIECTEEEMMMFAALQYHINKLSIMTSENHLTTDVNPECLVSPRYLKKYK--SKQIT 314 Query: 170 DRIQVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTD 215 RI H M A + +++ Q L +GI +F + + G Sbjct: 315 ARILEAHQNVAQMSLIEAKMRFIQAWQSLPEFGITHFIARFQGGKR 360 >2KMA-A nrPDB Length = 178 Score = 50.2 bits (118), Expect = 3e-06, Method: Composition-based stats. Identities = 16/91 (17%), Positives = 32/91 (35%), Gaps = 6/91 (6%) Query: 3 KPINVRVTTMDAEL-EFAIQPNTTGKQLFDQVVKTIGLREVWYFGLH---YVDNKGFPTW 58 K +++ +D + + + T + + IG+ + L + K W Sbjct: 90 KQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICARIGITNHDEYSLVRELMEEKKDELNW 149 Query: 59 LKLDKKVSAQEVRKENPLQFKFRAKFYPEDV 89 L + + Q V + L R KF+ D Sbjct: 150 LDHGRTLREQGVEEHETLLL--RRKFFYSDQ 178 >5XPY-A nrPDB Length = 474 Score = 45.9 bits (107), Expect = 5e-05, Method: Composition-based stats. Identities = 33/194 (17%), Positives = 69/194 (35%), Gaps = 33/194 (17%) Query: 52 NKGFPTWLKLDKKVSAQEVRKENPLQFKFR-AKFYPEDVAEELIQDITQKLFFLQVKEGI 110 K WL + + Q+V++ L +F+ F+ + + I + Q K + Sbjct: 186 AKTNQGWLDSSRSLMEQDVKENEALLLRFKYYSFFDLNPKYDA---IRINQLYEQAKWAL 242 Query: 111 LSDEIYCPPETAVLLGSYAVQA----------KFGDYNKEVH----------------KS 144 L +EI C E ++ + + +KEV K+ Sbjct: 243 LLEEIECTEEEMMMFAALQYHINKLSIMTSENHLNNSDKEVDEVDAALSDLEITLEGGKT 302 Query: 145 GYLSSERLIPQRVMDQHKLTRDQWED---RIQVWHAEHRGMLKDNAMLEYLKIAQDLEMY 201 + + + P+ ++ L + + + RI H M A + +++ Q L + Sbjct: 303 STILTTDVNPECLVSPRYLKKYKSKQITARILEAHQNVAQMSLIEAKMRFIQAWQSLPEF 362 Query: 202 GINYFEIKNKKGTD 215 GI +F + + G Sbjct: 363 GITHFIARFQGGKR 376 >3JCN-b nrPDB Length = 890 Score = 39.8 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 50/251 (19%), Positives = 94/251 (37%), Gaps = 19/251 (7%) Query: 292 MRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRL 351 +R+ D++ Q+ K + +QK +L ++K R T+ + ++ +R Sbjct: 29 IRKSADDSVSAQE-KQTLIDHLNQKNSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRK 87 Query: 352 QDYEEKTKKAERELSEQIQRALQLEEE----------RKRAQEEAERLEADRMAALRAKE 401 + K E E ++A + EE ++ AQ++AER EA A A E Sbjct: 88 KRTFVKRDPQEAERLAAEEQAQREAEEQARREAEESAKREAQQKAER-EAAEQAKREAAE 146 Query: 402 ELERQAVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKE 461 + +R+A ++ K Q A+ A E+ + + EE R E + V + Sbjct: 147 QAKREAAEKDKVSNQQDDMTKNAQAEKARREQEAAELKRKAEEEARRKLEEEARRVAEEA 206 Query: 462 ELHLVMTAPPPPPPPVYEPVSYHVQESLQDEGAE-------PTGYSAELSSEGIRDDRNE 514 P + YHV S AE G +++ R + Sbjct: 207 RRMAEENKWTDNAEPTEDSSDYHVTTSQHARQAEDESDREVEGGRGRGRNAKAARPKKGN 266 Query: 515 EKRITEAEKNE 525 + ++A++ E Sbjct: 267 KHAESKADREE 277 >5OFO-C nrPDB Length = 871 Score = 39.4 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 39/201 (19%), Positives = 81/201 (40%), Gaps = 20/201 (9%) Query: 297 PDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDY-- 354 +I +Q ++ +++ + +LE + +E+ E K+++ EEL + + Y Sbjct: 402 ASSIRMQIDSKPEELDRLDRRIIQLKLEQQALMKESDEASKKRLDMLNEELSDKERQYSE 461 Query: 355 -EEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALR--AKEELERQ--AVD 409 EE+ K + LS +LE+ + ++ + RM+ L+ ELE+Q A Sbjct: 462 LEEEWKAEKASLSGTQTIKAELEQAKIAIEQARRVGDLARMSELQYGKIPELEKQLEAAT 521 Query: 410 QIKSQ-------EQLAAELAEYTAK------IALLEEARRRKEDEVEEWQHRAKEAQDDL 456 Q++ + + AE+AE A+ ++E R + +E HR + + Sbjct: 522 QLEGKTMRLLRNKVTDAEIAEVLARWTGIPVSRMMESEREKLLRMEQELHHRVIGQNEAV 581 Query: 457 VKTKEELHLVMTAPPPPPPPV 477 + P P+ Sbjct: 582 DAVSNAIRRSRAGLADPNRPI 602 >1QVR-A nrPDB Length = 854 Score = 39.0 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 35/174 (20%), Positives = 73/174 (41%), Gaps = 19/174 (10%) Query: 280 ILQLCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQ 339 I+ +H RR PD + + A + + ++++ ++++ +E E+E Sbjct: 361 IIAAATLSHRYITERRLPDK-AIDLIDEAAARLRMALESAPEEIDALERKKLQLEIEREA 419 Query: 340 MMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRA 399 + +EK+ D +E+ K E E++ +L EE + + E ER LR Sbjct: 420 LKKEKDP------DSQERLKAIEAEIA-------KLTEEIAKLRAEWER----EREILRK 462 Query: 400 KEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQ 453 E + +D+++ + +LA + L + E EVE + + A+ Sbjct: 463 LREAQ-HRLDEVRREIELAERQYDLNRAAELRYGELPKLEAEVEALSEKLRGAR 515 Score = 33.6 bits (75), Expect = 0.26, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 46/97 (47%), Gaps = 1/97 (1%) Query: 358 TKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQL 417 + A E+ ++ LQLE ER+ ++E + +R+ A+ A+ + + +++++ + Sbjct: 396 LESAPEEIDALERKKLQLEIEREALKKEKDPDSQERLKAIEAEIAKLTEEIAKLRAEWER 455 Query: 418 AAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQD 454 E+ + + RR E E+ E Q+ A + Sbjct: 456 EREILRKLREAQHRLDEVRR-EIELAERQYDLNRAAE 491 >6D00-1 nrPDB Length = 883 Score = 39.0 bits (89), Expect = 0.006, Method: Composition-based stats. Identities = 26/128 (20%), Positives = 62/128 (48%), Gaps = 12/128 (9%) Query: 317 QLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLE 376 +LER+ L+ E + +E+EK+ ++ RLQ+ + + + EL R L+++ Sbjct: 411 KLERRHLQLEVEA-TALEKEKDAASKQ------RLQEVRAEMARIQEEL-----RPLKMK 458 Query: 377 EERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARR 436 E ++ + + R + R+ L+AK E + D ++ + + + ++A L+ + Sbjct: 459 YESEKGRLDEIRNLSQRLDELKAKAEDAERRYDLARAADIRYYAIPDLEKRLAQLQAEKS 518 Query: 437 RKEDEVEE 444 + + E + Sbjct: 519 QADAERAD 526 Score = 29.7 bits (65), Expect = 3.4, Method: Composition-based stats. Identities = 35/192 (18%), Positives = 66/192 (34%), Gaps = 25/192 (13%) Query: 369 IQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKI 428 +R LQLE E ++E + R+ +RA+ + QE+L +Y ++ Sbjct: 413 ERRHLQLEVEATALEKEKDAASKQRLQEVRAEMA---------RIQEELRPLKMKYESEK 463 Query: 429 ALLEEARRRKE--DEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEPVSYHVQ 486 L+E R + DE++ A+ D + + P E +Q Sbjct: 464 GRLDEIRNLSQRLDELKAKAEDAERRYDLARAADIRYYAI---------PDLEKRLAQLQ 514 Query: 487 ESLQDEGAEPTGYSAE--LSSEGIRDDRNEEKRITEAEKNERVQRQLLTLSSELSQ---A 541 AE + + I + + I + + +LL + + Q Sbjct: 515 AEKSQADAERADGLLAEVVGPDQIMEVVSRWTGIPVSNLQRSEKEKLLHMEEYMKQHVVG 574 Query: 542 RDENKRTHNDII 553 +DE + D I Sbjct: 575 QDEAIKAICDAI 586 >6ED3-A nrPDB Length = 848 Score = 39.0 bits (89), Expect = 0.006, Method: Composition-based stats. Identities = 24/117 (20%), Positives = 49/117 (41%), Gaps = 3/117 (2%) Query: 345 EELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELE 404 +E RL+ + E+ E + +LE E +E + A+R+A LR++ + Sbjct: 396 DEAASRLRM---EIDSRPVEIDEVERLVRRLEIEEMALSKEEDEASAERLAKLRSELADQ 452 Query: 405 RQAVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKE 461 ++ + ++ ++ Q E + EA R + + E AK A+ + E Sbjct: 453 KEKLAELTTRWQNEKNAIEIVRDLKEQLEALRGESERAERDGDLAKAAELRYGRIPE 509 >6FYX-o nrPDB Length = 964 Score = 38.2 bits (87), Expect = 0.009, Method: Composition-based stats. Identities = 30/186 (16%), Positives = 70/186 (37%), Gaps = 7/186 (3%) Query: 305 MKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERE 364 MK E+ +++E L+ E + + + + M++K ++ + E + Sbjct: 720 MKKLDHTERALRKVELPLLQKEVDKLQETDTANYEAMKKK--IVDAAKAEYEARMADRKN 777 Query: 365 LSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEY 424 L L+ +E +E L A R E ++ +++++ + + +A Sbjct: 778 LVMVYDDYLKFKEHVSGTKES--ELAAIRNQKKAELEAAKKARIEEVR-KRRYEEAIARR 834 Query: 425 TAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEPVSYH 484 +IA E R+++ E+ E + +E ++ K PP P P + Sbjct: 835 KEEIANAE--RQKRAQELAEATRKQREIEEAAAKKSTPYSFRAGNREPPSTPSTLPKATV 892 Query: 485 VQESLQ 490 + + Sbjct: 893 SPDKAK 898 >5EW5-A nrPDB Length = 582 Score = 38.2 bits (87), Expect = 0.010, Method: Composition-based stats. Identities = 45/284 (15%), Positives = 98/284 (34%), Gaps = 26/284 (9%) Query: 319 ERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEE 378 +RQ E +++ E R E L E + + E+ +A+Q+ Sbjct: 299 QRQDEENRRQQEWDATHPVEAAERNCERARAELNQANEDVARNQ----ERQAKAVQVYNS 354 Query: 379 RKRAQEEAERLEADRMAALRAKEELER------QAVDQIKSQEQLAAELAEYTAKIALLE 432 RK + A + AD +A ++ + Q+ + A+ + A Sbjct: 355 RKSELDAANKTLADAIAEIKQFNRFAHDPMAGGHRMWQMAGLKAQRAQTDVNNKQAAFDA 414 Query: 433 EARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEPVSYHVQESLQDE 492 A+ + + + + + Q + + + M + P + L D Sbjct: 415 AAKEKSDADAALSAAQERRKQKENKEKDAKDKCAMESKRNKPGKATGKGKPVGDKWLDDA 474 Query: 493 GAEPTGYSAELSSEGIRDDR---NEEKRIT---EAEKNERVQRQL-----LTLSSELSQA 541 G + + ++ +RD ++ R E K+ + + L ++S S Sbjct: 475 GKDSGAPIPDRIADKLRDKEFKSFDDFRKAVWEEVSKDPELSKNLNPSNKSSVSKGYSPF 534 Query: 542 RDENKRTHNDII----HNENMRQGRDKYKTLRQIRQGNTKQRID 581 +N++ + H++ + QG + Y + IR K+ ID Sbjct: 535 TPKNQQVGGRKVYELHHDKPISQGGEVYD-MDNIRVTTPKRHID 577 >3JAX-A nrPDB Length = 974 Score = 38.2 bits (87), Expect = 0.011, Method: Composition-based stats. Identities = 31/120 (25%), Positives = 63/120 (52%), Gaps = 9/120 (7%) Query: 331 ETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERK-RAQEEAERL 389 ++ EREKE M KEE RL++ EK++ +EL E++ LQ + + + + Q E + L Sbjct: 852 QSAEREKE-MASMKEEFT-RLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 909 Query: 390 -----EADRMAALRAKEELERQAVDQ-IKSQEQLAAELAEYTAKIALLEEARRRKEDEVE 443 D++ + + E + + +++ ++ +E++ AEL K+ +R D++E Sbjct: 910 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE 969 Score = 28.2 bits (61), Expect = 9.7, Method: Composition-based stats. Identities = 23/98 (23%), Positives = 48/98 (48%), Gaps = 7/98 (7%) Query: 294 RRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQD 353 RRK ++ + + + + Q Q E+ L ++R + + + K Q+ + +E+ RL+D Sbjct: 880 RRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLED 939 Query: 354 YEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEA 391 EE EL+ + + +LE+E + + + LE Sbjct: 940 EEE----MNAELTAKKR---KLEDECSELKRDIDDLEL 970 >1F5N-A nrPDB Length = 592 Score = 38.2 bits (87), Expect = 0.011, Method: Composition-based stats. Identities = 35/160 (21%), Positives = 73/160 (45%), Gaps = 24/160 (15%) Query: 294 RRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQD 353 R+ E+ Q +++E L+ Q TEK++ VER K + + +++ Sbjct: 452 RKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKML----- 506 Query: 354 YEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKS 413 + ++ ++ EQ +R+ Q E K+ E++E DR+ L+ E ER +++ Sbjct: 507 --HEMQRKNEQMMEQKERSYQ--EHLKQL---TEKMENDRVQLLK---EQERTLALKLQE 556 Query: 414 QEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQ 453 QEQL E ++ R ++E+++ Q + + + Sbjct: 557 QEQLLKEG---------FQKESRIMKNEIQDLQTKMRRRK 587 Score = 28.6 bits (62), Expect = 8.5, Method: Composition-based stats. Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 1/82 (1%) Query: 301 EVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKK 360 E+Q+ Q E+K + E + TEK + V+ KEQ +L + Q +E +K Sbjct: 508 EMQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQK 567 Query: 361 AERELSEQIQRALQLEEERKRA 382 R + +IQ LQ + R++A Sbjct: 568 ESRIMKNEIQD-LQTKMRRRKA 588 >3J3U-A nrPDB Length = 810 Score = 37.8 bits (86), Expect = 0.013, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 33/72 (45%), Gaps = 2/72 (2%) Query: 382 AQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDE 441 E ++ +ELE Q +D+++ ++ A + E+ +L + +R ++ Sbjct: 395 IDEAGSKVRLRSFTTPPNLKELE-QKLDEVRKEKDAAVQSQEFEKAASLRDTE-QRLREQ 452 Query: 442 VEEWQHRAKEAQ 453 VE+ + KE Q Sbjct: 453 VEDTKKSWKEKQ 464 >2KC2-A nrPDB Length = 128 Score = 37.4 bits (85), Expect = 0.015, Method: Composition-based stats. Identities = 9/38 (23%), Positives = 13/38 (34%), Gaps = 2/38 (5%) Query: 52 NKGFPTWLKLDKKVSAQEVRKENPLQFKFRAKFYPEDV 89 WL + + Q V + L R KF+ D Sbjct: 93 TDDELNWLDHGRTLREQGVEEHETLLL--RRKFFYSDQ 128 >3PXI-A nrPDB Length = 758 Score = 37.4 bits (85), Expect = 0.019, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 33/72 (45%), Gaps = 2/72 (2%) Query: 382 AQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDE 441 E ++ +ELE Q +D+++ ++ A + E+ +L + +R ++ Sbjct: 378 IDEAGSKVRLRSFTTPPNLKELE-QKLDEVRKEKDAAVQSQEFEKAASLRDTE-QRLREQ 435 Query: 442 VEEWQHRAKEAQ 453 VE+ + KE Q Sbjct: 436 VEDTKKSWKEKQ 447 >4ZRJ-B nrPDB Length = 90 Score = 37.1 bits (84), Expect = 0.022, Method: Composition-based stats. Identities = 24/74 (32%), Positives = 44/74 (59%), Gaps = 1/74 (1%) Query: 514 EEKRITEAEKNERVQRQLLTLSSELSQARDENKRTHNDIIHNENM-RQGRDKYKTLRQIR 572 E++++ EK++ +Q QL L +E+ + + + T DI+HNEN R G K+ T++++ Sbjct: 17 EKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKLT 76 Query: 573 QGNTKQRIDEFEAL 586 + K R+ FE L Sbjct: 77 LQSWKSRVAFFEEL 90 >3PXG-A nrPDB Length = 468 Score = 37.1 bits (84), Expect = 0.024, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 33/72 (45%), Gaps = 2/72 (2%) Query: 382 AQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDE 441 E ++ +ELE Q +D+++ ++ A + E+ +L + +R ++ Sbjct: 378 IDEAGSKVRLRSFTTPPNLKELE-QKLDEVRKEKDAAVQSQEFEKAASLRDTE-QRLREQ 435 Query: 442 VEEWQHRAKEAQ 453 VE+ + KE Q Sbjct: 436 VEDTKKSWKEKQ 447 >5IJN-G nrPDB Length = 599 Score = 36.7 bits (83), Expect = 0.026, Method: Composition-based stats. Identities = 19/132 (14%), Positives = 53/132 (40%), Gaps = 1/132 (0%) Query: 338 EQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEE-RKRAQEEAERLEADRMAA 396 ++ ++E++++ + K +E + +++ L L +R ++L+ + Sbjct: 259 QKFVKEQKQVQEEISRMSSKAMLKVQEDIKALKQLLSLAANGIQRNTLNIDKLKIETAQE 318 Query: 397 LRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDL 456 L+ E R Q + AA + + E ++ ++EE ++ ++ Sbjct: 319 LKNAEIALRTQKTPPGLQHEYAAPADYFRILVQQFEVQLQQYRQQIEELENHLATQANNS 378 Query: 457 VKTKEELHLVMT 468 T ++L + M Sbjct: 379 HITPQDLSMAMQ 390 >4CIU-A nrPDB Length = 727 Score = 36.3 bits (82), Expect = 0.035, Method: Composition-based stats. Identities = 38/201 (18%), Positives = 80/201 (39%), Gaps = 20/201 (9%) Query: 297 PDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDY-- 354 +I +Q ++ +++ + +LE + + + E K+++ EEL + + Y Sbjct: 256 ASSIRMQIDSKPEELDRLDRRIIQLKLEQQALMKASDEASKKRLDMLNEELSDKERQYSE 315 Query: 355 -EEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALR--AKEELERQ--AVD 409 EE+ K + LS +LE+ + ++ + RM+ L+ ELE+Q A Sbjct: 316 LEEEWKAEKASLSGTQTIKAELEQAKIAIEQARRVGDLARMSELQYGKIPELEKQLEAAT 375 Query: 410 QIKSQ-------EQLAAELAEYTAK------IALLEEARRRKEDEVEEWQHRAKEAQDDL 456 Q++ + + AE+AE A+ ++E R + +E HR + + Sbjct: 376 QLEGKTMRLLRNKVTDAEIAEVLARWTGIPVSRMMESEREKLLRMEQELHHRVIGQNEAV 435 Query: 457 VKTKEELHLVMTAPPPPPPPV 477 + P P+ Sbjct: 436 DAVSNAIRRSRAGLADPNRPI 456 >3D2D-A nrPDB Length = 538 Score = 36.3 bits (82), Expect = 0.035, Method: Composition-based stats. Identities = 34/192 (17%), Positives = 70/192 (36%), Gaps = 23/192 (11%) Query: 18 FAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKLDKKVSAQEVRKENPLQ 77 F T K FD + +GL E Y + + ++ + L+ V + N Sbjct: 297 FHFGLKTVAKSTFDLLFPELGLVEEDYLEMSWGESFAYLAGLE--------TVSQLNNRF 348 Query: 78 FKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQ-AKF-G 135 KF + + V + + + K F+ G+L + + P + L + Q +K Sbjct: 349 LKFDERAFKTKV-DLTKEPLPSKAFY-----GLL-ERLSKEPNGFIALNGFGGQMSKISS 401 Query: 136 DYNKEVHKSGYLSSERLIP--QRVMDQHKLTRDQWEDRIQVWHAEHRGMLKDNAMLEYLK 193 D+ H+SG I + + K W +++ + + ++ Sbjct: 402 DFTPFPHRSGTRLMVEYIVAWNQSEQKKKTEFLDWLEKVYEFMKPFVSKNPRLGYVNHI- 460 Query: 194 IAQDLEMYGINY 205 DL++ GI++ Sbjct: 461 ---DLDLGGIDW 469 >2QAG-C nrPDB Length = 418 Score = 35.9 bits (81), Expect = 0.056, Method: Composition-based stats. Identities = 28/106 (26%), Positives = 58/106 (54%), Gaps = 11/106 (10%) Query: 313 KHQKQLERQQL-ETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELS---EQ 368 K++ QL + L + E++RRE V + K+ M ++ +++++ +K K +E EL EQ Sbjct: 307 KNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQ 366 Query: 369 IQRALQ-----LEEERKRAQEEAERLEADR--MAALRAKEELERQA 407 +++ L+ LEE+R++ ++E EA + + + LE+ Sbjct: 367 MKKNLEAQHKELEEKRRQFEDEKANWEAQQRILEQQNSSRTLEKNK 412 Score = 30.5 bits (67), Expect = 2.3, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 42/79 (53%), Gaps = 2/79 (2%) Query: 374 QLEEERKR--AQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALL 431 Q+EEER+ A+ + +E +++ ++ KE++++ + + Q + A+ L Sbjct: 319 QMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKEL 378 Query: 432 EEARRRKEDEVEEWQHRAK 450 EE RR+ EDE W+ + + Sbjct: 379 EEKRRQFEDEKANWEAQQR 397 Score = 28.6 bits (62), Expect = 8.7, Method: Composition-based stats. Identities = 20/70 (28%), Positives = 35/70 (50%), Gaps = 4/70 (5%) Query: 294 RRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRR----ETVEREKEQMMREKEELML 349 + K ++ + + Q R E+ +K LE Q E E+KRR E E +Q + E++ Sbjct: 347 KEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDEKANWEAQQRILEQQNSSR 406 Query: 350 RLQDYEEKTK 359 L+ ++K K Sbjct: 407 TLEKNKKKGK 416 >4HSE-A nrPDB Length = 397 Score = 35.5 bits (80), Expect = 0.064, Method: Composition-based stats. Identities = 35/174 (20%), Positives = 73/174 (41%), Gaps = 19/174 (10%) Query: 280 ILQLCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQ 339 I+ +H RR PD + + A + + ++++ ++++ +E E+E Sbjct: 224 IIAAATLSHRYITERRLPDK-AIDLIDEAAARLRMALESAPEEIDALERKKLQLEIEREA 282 Query: 340 MMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRA 399 + +EK+ D +E+ K E E++ +L EE + + E ER LR Sbjct: 283 LKKEKDP------DSQERLKAIEAEIA-------KLTEEIAKLRAEWER----EREILRK 325 Query: 400 KEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQ 453 E + +D+++ + +LA + L + E EVE + + A+ Sbjct: 326 LREAQ-HRLDEVRREIELAERQYDLNRAAELRYGELPKLEAEVEALSEKLRGAR 378 Score = 31.7 bits (70), Expect = 0.99, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 46/97 (47%), Gaps = 1/97 (1%) Query: 358 TKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQL 417 + A E+ ++ LQLE ER+ ++E + +R+ A+ A+ + + +++++ + Sbjct: 259 LESAPEEIDALERKKLQLEIEREALKKEKDPDSQERLKAIEAEIAKLTEEIAKLRAEWER 318 Query: 418 AAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQD 454 E+ + + RR E E+ E Q+ A + Sbjct: 319 EREILRKLREAQHRLDEVRR-EIELAERQYDLNRAAE 354 >3KYC-B nrPDB Length = 660 Score = 35.1 bits (79), Expect = 0.082, Method: Composition-based stats. Identities = 30/147 (20%), Positives = 65/147 (44%), Gaps = 7/147 (4%) Query: 413 SQEQLAAELAEYT--AKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAP 470 S E+ E + ++ + +R + +D ++++ + + E +V AP Sbjct: 512 SSEEGETEANNHKKLSEFGIRNGSRLQADDFLQDYTLLINILHSEDLGKDVEFEVVGDAP 571 Query: 471 PPPPPPVYEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAE--KNERVQ 528 P E + + + D+GA+P+ +A+ + + D +EE A+ + ER + Sbjct: 572 EKVGPKQAEDAAKSI-TNGSDDGAQPSTSTAQEQDDVLIVDSDEEDSSNNADVSEEERSR 630 Query: 529 RQLLTLSSELS--QARDENKRTHNDII 553 ++ L LS ++R E K +D+I Sbjct: 631 KRKLDEKENLSAKRSRIEQKEELDDVI 657 >5M6U-B nrPDB Length = 724 Score = 34.4 bits (77), Expect = 0.13, Method: Composition-based stats. Identities = 34/152 (22%), Positives = 63/152 (41%), Gaps = 3/152 (1%) Query: 311 EEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQ 370 EE+ Q Q + EK +RE E E +++M E+L R+ + + ++ E +L +Q Sbjct: 495 EEQCQTQERYSKEYIEKFKREGNETEIQRIMHNYEKLKSRISEIVDSRRRLEEDLKKQ-- 552 Query: 371 RALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIAL 430 A + E KR L R + L ++ V Q K E L E E + Sbjct: 553 -AAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVE 611 Query: 431 LEEARRRKEDEVEEWQHRAKEAQDDLVKTKEE 462 +E +++ + ++L++ K + Sbjct: 612 DDEDLPHHDEKTWNVGSSNRNKAENLLRGKRD 643 >5ZLU-EE nrPDB Length = 497 Score = 34.4 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 23/112 (20%), Positives = 48/112 (42%), Gaps = 6/112 (5%) Query: 310 REEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQI 369 R+++ ++Q + + E K RE +E ++ + ++ L + EK+K + Sbjct: 186 RQKEEERQHQAVEYELMMKERERLESAVQE--KRQQANRLDNKKKGEKSKNSTESAGRLG 243 Query: 370 QRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAEL 421 + ++RK Q R+AAL + E + I+ ++ A EL Sbjct: 244 HAKMTGTKQRKLYQAAKSM--EKRLAALEDIQAPEH--LRSIRFRQSSALEL 291 >3LJ5-A nrPDB Length = 725 Score = 34.4 bits (77), Expect = 0.15, Method: Composition-based stats. Identities = 32/178 (17%), Positives = 73/178 (41%), Gaps = 39/178 (21%) Query: 292 MRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRL 351 M +KP+T E QQ +A++ K +Q + M + + ++L Sbjct: 579 MGVKKPETPEEQQWLVEAQQAKQGQQ--------------------DPAMVQAQGVLL-- 616 Query: 352 QDYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQA---- 407 + + EL++ + L L+ + + E +L A R+A + +L +Q+ Sbjct: 617 --------QGQAELAKAQNQTLSLQIDAAKV-EAQNQLNAARIAEIFNNMDLSKQSEFRE 667 Query: 408 -VDQIKSQEQLAAELAEYTAKIALL-EEARRRKEDEVEEWQHRAKEAQ--DDLVKTKE 461 + + S +Q +E A A++ L +E ++ ++ ++ Q + +T + Sbjct: 668 FLKTVASFQQDRSEDARANAELLLKGDEQTHKQRMDIANILQSQRQNQPSGSVAETPQ 725 >5Y5Z-N nrPDB Length = 652 Score = 34.0 bits (76), Expect = 0.18, Method: Composition-based stats. Identities = 39/163 (23%), Positives = 70/163 (42%), Gaps = 20/163 (12%) Query: 318 LERQQLETEKKRRETVEREKEQMMREKEELMLR--LQDYEEKTKKAERELSEQIQRALQL 375 + R++++ K + ++ EL L + +E+ + A RELSE Q +L Sbjct: 182 VHRKEVDQAKAALSRAGVAELRLPGALGELPLSEAARRLKERAEAAPRELSEVRQHLAKL 241 Query: 376 EEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEAR 435 A+E A L++ RA++E+ R +K+ E+LA+ + ALL Sbjct: 242 ------ARESASTLQS---LWTRAQDEVAR-----LKALEELAS--GRFG--FALLGYVP 283 Query: 436 RRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVY 478 + + +VEE R KE+ + +E H P P + Sbjct: 284 VKAKPKVEEALARHKESVVYAFEPVDEHHEADRIPVVLDNPPW 326 >5FWP-E nrPDB Length = 378 Score = 33.6 bits (75), Expect = 0.24, Method: Composition-based stats. Identities = 19/74 (25%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Query: 377 EERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARR 436 E ++ Q+E E L+ R E +R + +++ E AEL A+ L + R Sbjct: 38 ERMEQFQKEKEELDRGCRECKRKVAECQR-KLKELEVAEGGKAELERLQAEAQQLRKEER 96 Query: 437 RKEDEVEEWQHRAK 450 E ++EE + + K Sbjct: 97 SWEQKLEEMRKKEK 110 Score = 31.3 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 33/168 (19%), Positives = 69/168 (41%), Gaps = 16/168 (9%) Query: 298 DTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEK 357 D IEV + + L R + + +R E ++EKE++ R E ++ + + K Sbjct: 8 DHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRK 67 Query: 358 TKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQL 417 K +++ A + E +R Q EA++L R +E Q +++++ +E+ Sbjct: 68 LK--------ELEVAEGGKAELERLQAEAQQL--------RKEERSWEQKLEEMRKKEKS 111 Query: 418 AAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHL 465 + +K + K ++ EE +E + K E + Sbjct: 112 MPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQI 159 >6BP7-A nrPDB Length = 934 Score = 33.2 bits (74), Expect = 0.31, Method: Composition-based stats. Identities = 35/175 (20%), Positives = 66/175 (37%), Gaps = 29/175 (16%) Query: 311 EEKHQKQLERQ-QLETEKKRRETVEREKEQMMREKEELMLRLQDY----EEKTKKAEREL 365 +++ + L+R QL E K + R ++E RL+ + + +KA +EL Sbjct: 720 DQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKEL 779 Query: 366 SEQIQRALQLEE------------ERKRAQEEAERLEADRMAALRAKE-ELERQAVDQIK 412 E ++ +E E R + E L+A A A E E E + V +++ Sbjct: 780 LELEAMSMAVESTGNAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELERVKKVR 839 Query: 413 ------SQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKE 461 ++ QL E+++ L ++ ++ E D V E Sbjct: 840 EMELIYARAQLELEVSKAQQ---LANVEAKKFKEMTEALGPGTIR--DLAVAGPE 889 >4TKO-B nrPDB Length = 358 Score = 33.2 bits (74), Expect = 0.33, Method: Composition-based stats. Identities = 31/156 (19%), Positives = 75/156 (48%), Gaps = 10/156 (6%) Query: 292 MRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRL 351 + ++K I++Q+++ K+L ++E+ KK+RE + + Q+ + + + L Sbjct: 71 LEKKKALEIKIQKLEKGLHISLSAKKL---KVESLKKKREALREKLLQVEEKIKLVKLDW 127 Query: 352 QDYEEKTKKA--ERELSEQIQRALQ-LEEERKRAQEEAERLEADRMAALRAKEELERQAV 408 + Y+ +K R E++ L+ L ER+ ++ + + + A + E Sbjct: 128 ERYKSLFQKGLIPRRKFEEVDTNLKVLLHEREYLEKSIQEINTEIKRAKKGIENAR---- 183 Query: 409 DQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEE 444 ++ K+ E+L EL+ +I L+E + E ++++ Sbjct: 184 NEFKTIEELKKELSSLEEEIKSLKERIKTAEQKIKD 219 >5KTG-A nrPDB Length = 311 Score = 33.2 bits (74), Expect = 0.36, Method: Composition-based stats. Identities = 23/134 (17%), Positives = 44/134 (32%), Gaps = 16/134 (11%) Query: 113 DEIYCPPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRI 172 ++ P T V Y VQ F Y ++ + + ++R Sbjct: 51 GKLPVPWPTLVTTFGYGVQC-FARY------PDHMKQHDFF------KSAMPEGYVQERT 97 Query: 173 QVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDD 232 + + + E + +E+ GI++ E N G L ++ + I Sbjct: 98 IFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQ 157 Query: 233 KLTPKIGFPWSEIR 246 K K+ F +IR Sbjct: 158 KNGIKVNF---KIR 168 >4Z4M-A nrPDB Length = 262 Score = 33.2 bits (74), Expect = 0.36, Method: Composition-based stats. Identities = 23/134 (17%), Positives = 44/134 (32%), Gaps = 16/134 (11%) Query: 113 DEIYCPPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRI 172 ++ P T V Y VQ F Y ++ + + ++R Sbjct: 54 GKLPVPWPTLVTTFGYGVQC-FARY------PDHMKQHDFF------KSAMPEGYVQERT 100 Query: 173 QVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDD 232 + + + E + +E+ GI++ E N G L ++ + I Sbjct: 101 IFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQ 160 Query: 233 KLTPKIGFPWSEIR 246 K K+ F +IR Sbjct: 161 KNGIKVNF---KIR 171 >4U2V-B nrPDB Length = 315 Score = 33.2 bits (74), Expect = 0.36, Method: Composition-based stats. Identities = 23/134 (17%), Positives = 44/134 (32%), Gaps = 16/134 (11%) Query: 113 DEIYCPPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRI 172 ++ P T V Y VQ F Y ++ + + ++R Sbjct: 54 GKLPVPWPTLVTTFGYGVQC-FARY------PDHMKQHDFF------KSAMPEGYVQERT 100 Query: 173 QVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDD 232 + + + E + +E+ GI++ E N G L ++ + I Sbjct: 101 IFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQ 160 Query: 233 KLTPKIGFPWSEIR 246 K K+ F +IR Sbjct: 161 KNGIKVNF---KIR 171 >4JRB-A nrPDB Length = 418 Score = 33.2 bits (74), Expect = 0.36, Method: Composition-based stats. Identities = 23/134 (17%), Positives = 44/134 (32%), Gaps = 16/134 (11%) Query: 113 DEIYCPPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRI 172 ++ P T V Y VQ F Y ++ + + ++R Sbjct: 54 GKLPVPWPTLVTTFGYGVQC-FARY------PDHMKQHDFF------KSAMPEGYVQERT 100 Query: 173 QVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDD 232 + + + E + +E+ GI++ E N G L ++ + I Sbjct: 101 IFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQ 160 Query: 233 KLTPKIGFPWSEIR 246 K K+ F +IR Sbjct: 161 KNGIKVNF---KIR 171 >3VHT-B nrPDB Length = 273 Score = 33.2 bits (74), Expect = 0.36, Method: Composition-based stats. Identities = 23/134 (17%), Positives = 44/134 (32%), Gaps = 16/134 (11%) Query: 113 DEIYCPPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRI 172 ++ P T V Y VQ F Y ++ + + ++R Sbjct: 54 GKLPVPWPTLVTTFGYGVQC-FARY------PDHMKQHDFF------KSAMPEGYVQERT 100 Query: 173 QVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDD 232 + + + E + +E+ GI++ E N G L ++ + I Sbjct: 101 IFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQ 160 Query: 233 KLTPKIGFPWSEIR 246 K K+ F +IR Sbjct: 161 KNGIKVNF---KIR 171 >4BDU-A nrPDB Length = 311 Score = 32.8 bits (73), Expect = 0.41, Method: Composition-based stats. Identities = 23/134 (17%), Positives = 44/134 (32%), Gaps = 16/134 (11%) Query: 113 DEIYCPPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRI 172 ++ P T V Y VQ F Y ++ + + ++R Sbjct: 54 GKLPVPWPTLVTTFGYGVQC-FSRY------PDHMKQHDFF------KSAMPEGYVQERT 100 Query: 173 QVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDD 232 + + + E + +E+ GI++ E N G L ++ + I Sbjct: 101 IFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQ 160 Query: 233 KLTPKIGFPWSEIR 246 K K+ F +IR Sbjct: 161 KNGIKVNF---KIR 171 >4Z4K-A nrPDB Length = 292 Score = 32.8 bits (73), Expect = 0.46, Method: Composition-based stats. Identities = 23/134 (17%), Positives = 44/134 (32%), Gaps = 16/134 (11%) Query: 113 DEIYCPPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRI 172 ++ P T V Y VQ F Y ++ + + ++R Sbjct: 54 GKLPVPWPTLVTTFGYGVQC-FARY------PDHMKQHDFF------KSAMPEGYVQERT 100 Query: 173 QVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDD 232 + + + E + +E+ GI++ E N G L ++ + I Sbjct: 101 IFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQ 160 Query: 233 KLTPKIGFPWSEIR 246 K K+ F +IR Sbjct: 161 KNGIKVNF---KIR 171 >5OOL-q nrPDB Length = 222 Score = 32.4 bits (72), Expect = 0.55, Method: Composition-based stats. Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 19/103 (18%) Query: 314 HQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRAL 373 Q+ L +QL E+KRRE + E M + + ++ Q E +KA+ + Sbjct: 99 MQESLRVKQLAEEQKRREREQHIAECMAKMPQMIVNWQQQQRENWEKAQAD--------- 149 Query: 374 QLEEERKRAQEEAERL--------EADRMAALRAKEELERQAV 408 +E R R Q EA+ L A L+ E+ ER+ + Sbjct: 150 --KERRARLQAEAQELLGYQVDPRSARFQELLQDLEKKERKRL 190 >6GAZ-Ad nrPDB Length = 205 Score = 32.4 bits (72), Expect = 0.56, Method: Composition-based stats. Identities = 22/112 (19%), Positives = 45/112 (40%) Query: 302 VQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKA 361 + +++ + E + Q ER+ E + RE + + + R E + RL+ + ++ Sbjct: 75 MSEVRKKLHEARAGVQAERKAQEDAAEHRELMAWNQAENQRLHELRLARLRQEALEQERR 134 Query: 362 ERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKS 413 + E + R Q + K + + EA E +A+D KS Sbjct: 135 QAEEAVLQAREAQAWAQLKEQEVLQLQEEAKTFITRENLEARVEEALDSPKS 186 Score = 29.7 bits (65), Expect = 3.5, Method: Composition-based stats. Identities = 23/118 (19%), Positives = 50/118 (42%), Gaps = 5/118 (4%) Query: 331 ETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLE 390 E + ++ + + E M ++ + + + + + A + E Q E +RL Sbjct: 58 ERYRQYRQTVRALRLEFMSEVRKKLHEARAGVQAERKAQEDAAEHRELMAWNQAENQRLH 117 Query: 391 ADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHR 448 R+A LR +E LE++ + E+ + E A L E+ + ++E + + R Sbjct: 118 ELRLARLR-QEALEQER----RQAEEAVLQAREAQAWAQLKEQEVLQLQEEAKTFITR 170 >5FGU-A nrPDB Length = 567 Score = 32.0 bits (71), Expect = 0.65, Method: Composition-based stats. Identities = 23/134 (17%), Positives = 44/134 (32%), Gaps = 16/134 (11%) Query: 113 DEIYCPPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRI 172 ++ P T V Y VQ F Y ++ + + ++R Sbjct: 54 GKLPVPWPTLVTTFGYGVQC-FARY------PDHMKQHDFF------KSAMPEGYVQERT 100 Query: 173 QVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDD 232 + + + E + +E+ GI++ E N G L ++ + I Sbjct: 101 IFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQ 160 Query: 233 KLTPKIGFPWSEIR 246 K K+ F +IR Sbjct: 161 KNGIKVNF---KIR 171 >3AI5-A nrPDB Length = 309 Score = 32.0 bits (71), Expect = 0.66, Method: Composition-based stats. Identities = 23/134 (17%), Positives = 44/134 (32%), Gaps = 16/134 (11%) Query: 113 DEIYCPPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRI 172 ++ P T V Y VQ F Y ++ + + ++R Sbjct: 54 GKLPVPWPTLVTTFGYGVQC-FARY------PDHMKQHDFF------KSAMPEGYVQERT 100 Query: 173 QVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDD 232 + + + E + +E+ GI++ E N G L ++ + I Sbjct: 101 IFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQ 160 Query: 233 KLTPKIGFPWSEIR 246 K K+ F +IR Sbjct: 161 KNGIKVNF---KIR 171 >3K2S-A nrPDB Length = 243 Score = 32.0 bits (71), Expect = 0.68, Method: Composition-based stats. Identities = 38/180 (21%), Positives = 74/180 (41%), Gaps = 16/180 (8%) Query: 307 AQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELS 366 +Q KQL + L+ T + +EQ+ +E L+ E ++ + Sbjct: 31 SQFEGSALGKQLNLKLLDNWDSVTSTFSKLREQLGPVTQEFWDNLEKETEGLRQEMSKDL 90 Query: 367 EQIQRALQ--LEEERKRAQEEAERLEADRMAALRA-KEELERQAVDQIKSQEQLAAELAE 423 E+++ +Q L++ +K+ QEE E L ++ LRA +E RQ + +++ + E Sbjct: 91 EEVKAKVQPYLDDFQKKWQEEME-LYRQKVEPLRAELQEGARQKLHELQEKLSPLGEEMR 149 Query: 424 YTAKIAL----------LEEARRRKEDEVEEWQHR--AKEAQDDLVKTKEELHLVMTAPP 471 A+ + +E R+R +E + A+ A+ T+ L A P Sbjct: 150 DRARAHVDALRTHLAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAKP 209 >5AMO-A nrPDB Length = 471 Score = 32.0 bits (71), Expect = 0.69, Method: Composition-based stats. Identities = 25/145 (17%), Positives = 61/145 (42%), Gaps = 19/145 (13%) Query: 338 EQMMREKEELMLRLQDYEEKTK-----------KAERELSEQIQRALQ---LEEERKRAQ 383 +Q M ++ +L+ EK + + +R+L + Q LE + K+ + Sbjct: 65 QQTMCSRDARTKQLRQLLEKVQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLETKFKQVE 124 Query: 384 EEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEV- 442 E ++ A + A++AK + R + ++ + A + ++ ++ L ++E+ Sbjct: 125 ESHKQHLARQFKAIKAKMDELRPLIPVLEEYKADAKLVLQFKEEVQNLTSVLNELQEEIG 184 Query: 443 ----EEWQHRAKEAQDDLVKTKEEL 463 +E Q R ++ L ++L Sbjct: 185 AYDYDELQSRVSNLEERLRACMQKL 209 >1UUN-A nrPDB Length = 184 Score = 32.0 bits (71), Expect = 0.70, Method: Composition-based stats. Identities = 16/54 (29%), Positives = 23/54 (42%), Gaps = 2/54 (3%) Query: 220 VDALGLNIYEKDDKLTPKIGFPWS--EIRNISFNDKKFVIKPIDKKAPDFVFYA 271 V G + +E +L +IGFPWS N S+ +I D P F + Sbjct: 50 VAGPGADEFEGTLELGYQIGFPWSLGVGINFSYTTPNILIDDGDITRPPFGLNS 103 >3VHL-A nrPDB Length = 288 Score = 32.0 bits (71), Expect = 0.71, Method: Composition-based stats. Identities = 30/153 (19%), Positives = 61/153 (39%), Gaps = 14/153 (9%) Query: 228 YEKDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINK-------RI 280 + ++ LT FP+ + R ++FV+ PI+ D +L + ++ Sbjct: 135 HRRNTVLTTMHAFPYIKTRIRVSQKEEFVLTPIEVAIEDMKKKTLQLAVATHQEPPDAKM 194 Query: 281 LQLCMGNHELYMRRRKPDTIEVQQ-----MKAQAREEKHQKQLERQQLETEKKRRETVER 335 LQ+ + + P +EV Q + A + +H +L E + E VE+ Sbjct: 195 LQMVLQGSVGATVNQGP--LEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEK 252 Query: 336 EKEQMMREKEELMLRLQDYEEKTKKAERELSEQ 368 + + E+ E L+ K + + R + E+ Sbjct: 253 NRRLITAEQREYQQELKKNYNKLRDSLRPMIER 285 >4RSI-B nrPDB Length = 397 Score = 32.0 bits (71), Expect = 0.72, Method: Composition-based stats. Identities = 19/121 (15%), Positives = 50/121 (41%), Gaps = 6/121 (4%) Query: 322 QLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKR 381 QL+ ++ + + E E + + +L ++ EEK + E L L+++ Sbjct: 10 QLQEKESQIQLAESELSLLEETQAKLKKNVETLEEKILAKKTHKQELQDLILDLKKKLNS 69 Query: 382 AQEEAERLEAD------RMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEAR 435 ++E + E + ++ ++ RQ + +S A ++ ++ L+++ Sbjct: 70 LKDERSQGEKNFTSAHLKLKEMQKVLNAHRQRAMEARSSLSKAQNKSKVLTALSRLQKSG 129 Query: 436 R 436 R Sbjct: 130 R 130 Score = 29.3 bits (64), Expect = 4.9, Method: Composition-based stats. Identities = 22/85 (25%), Positives = 39/85 (45%), Gaps = 3/85 (3%) Query: 319 ERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEE 378 E ++E E RE R + E EE + +L+D+E E ++S+ A L E Sbjct: 296 EVDKIERELSERENNFRVASDTVHEMEEELKKLRDHEPDL---ESQISKAEMEADSLASE 352 Query: 379 RKRAQEEAERLEADRMAALRAKEEL 403 A+++ + E + A+ K +L Sbjct: 353 LTLAEQQVKEAEMAYVKAVSDKAQL 377 >5VY8-A nrPDB Length = 908 Score = 32.0 bits (71), Expect = 0.78, Method: Composition-based stats. Identities = 25/139 (17%), Positives = 51/139 (36%), Gaps = 19/139 (13%) Query: 311 EEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQ 370 EE K+ + Q ++ E K E E + + +E+ + + +E+ Sbjct: 412 EELDSKERQLQLIQVEIKALERDEDADSTTKDRLKLARQKEASLQEELEPLRQRYNEEKH 471 Query: 371 RALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIAL 430 EE +A+++ + LE + A R D + + + + +I Sbjct: 472 G----HEELTQAKKKLDELENKALDAER--------RYDTATAADLRYFAIPDIKKQIE- 518 Query: 431 LEEARRRKEDEVEEWQHRA 449 + ED+V E + RA Sbjct: 519 ------KLEDQVAEEERRA 531 Score = 30.5 bits (67), Expect = 2.3, Method: Composition-based stats. Identities = 38/199 (19%), Positives = 69/199 (34%), Gaps = 19/199 (9%) Query: 357 KTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQ 416 +K E + E+ + +Q+E + E+A+ DR+ R KE ++ ++ ++ Sbjct: 408 DSKPEELDSKERQLQLIQVEIKALERDEDADSTTKDRLKLARQKEASLQEELEPLR---- 463 Query: 417 LAAELAEYTAKIALLEEAR--RRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPP 474 Y + EE ++K DE+E A+ D + P Sbjct: 464 -----QRYNEEKHGHEELTQAKKKLDELENKALDAERRYDTATAADLRYFAI-----PDI 513 Query: 475 PPVYEPVSYHVQESLQDEGAEP---TGYSAELSSEGIRDDRNEEKRITEAEKNERVQRQL 531 E + V E + GA ++ SE + +NE++ Sbjct: 514 KKQIEKLEDQVAEEERRAGANSMIQNVVDSDTISETAARLTGIPVKKLSESENEKLIHME 573 Query: 532 LTLSSELSQARDENKRTHN 550 LSSE+ D K N Sbjct: 574 RDLSSEVVGQMDAIKAVSN 592 >5C8J-I nrPDB Length = 207 Score = 31.7 bits (70), Expect = 0.84, Method: Composition-based stats. Identities = 10/49 (20%), Positives = 25/49 (51%), Gaps = 1/49 (2%) Query: 334 EREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRA 382 ++ ++ +E +E ++ + + + E+ L E+ QR +QL E + Sbjct: 51 QKRVAELKKEIQEFQVKFKKMSKNPEMMEK-LQEEQQRIMQLNAELMKM 98 >3AI4-A nrPDB Length = 285 Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 23/134 (17%), Positives = 44/134 (32%), Gaps = 16/134 (11%) Query: 113 DEIYCPPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRI 172 ++ P T V Y VQ F Y ++ + + ++R Sbjct: 54 GKLPVPWPTLVTTFGYGVQC-FARY------PDHMKQHDFF------KSAMPEGYVQERT 100 Query: 173 QVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDD 232 + + + E + +E+ GI++ E N G L ++ + I Sbjct: 101 IFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQ 160 Query: 233 KLTPKIGFPWSEIR 246 K K+ F +IR Sbjct: 161 KNGIKVNF---KIR 171 >3TBI-B nrPDB Length = 228 Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 29/124 (23%), Positives = 55/124 (44%), Gaps = 13/124 (10%) Query: 323 LETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRA 382 ++ + R+ VE++K + E+ +L +D E+ + E L +I+ L Sbjct: 100 IDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIRAVL--------- 150 Query: 383 QEEAERLEADRMAALRAKEELERQAVDQIKSQE--QLAAELAEYTAKIALLEEARRRKED 440 A +EA+++ L LE D+ K + QLA + E + EA+RRK Sbjct: 151 --VAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKIT 208 Query: 441 EVEE 444 + ++ Sbjct: 209 QGDD 212 >4PZA-A nrPDB Length = 223 Score = 31.3 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 27/143 (18%), Positives = 43/143 (30%), Gaps = 4/143 (2%) Query: 412 KSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPP 471 + Q QL EL+E A+ K + + A D VK E LV+ Sbjct: 21 RMQGQLDTELSELGRTQAVAAAEVLGKRQPLLIVSSDLRRAYDTAVKLGERTGLVVRVDT 80 Query: 472 PPPPPVYEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQRQL 531 + A+ G + E R+ A ++ + +L Sbjct: 81 RLRETHLGDWQGLTHAQID---ADAPGARLAWREDATWAPHGGESRVDVAARSRPLVAEL 137 Query: 532 LTLSSELSQARDENKRTHNDIIH 554 + E A DE R + H Sbjct: 138 VASEPEWGGA-DEPDRPVVLVAH 159 >5D4W-A nrPDB Length = 926 Score = 31.3 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 25/104 (24%), Positives = 50/104 (48%), Gaps = 2/104 (1%) Query: 294 RRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEEL-MLRLQ 352 RR PD+ V + A + ++ + + +++ ++R ++ E + REK+E RL Sbjct: 402 RRLPDS-AVDLIDEAAAAVRVARESQPEIIDSLERRLRQLKIEIHALSREKDEASKARLA 460 Query: 353 DYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAA 396 ++ + E EL ++ + + K QE +LEA R+ A Sbjct: 461 QAKQDAQNVEEELRPLREKYERERQRGKAIQEAKMKLEALRVKA 504 >2V71-A nrPDB Length = 189 Score = 31.3 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 34/171 (19%), Positives = 72/171 (42%), Gaps = 8/171 (4%) Query: 299 TIEVQQMKAQAREEKHQKQLERQQLETEKKRR-ETVEREKEQMMREKEELMLRLQDYEEK 357 +++ +Q +AR+E + Q ++LE E + + E+ + + + L ++ +EK Sbjct: 19 SMKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEK 78 Query: 358 TKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQL 417 + + +Q+ LE++ + + E+L +A ++LER I S E Sbjct: 79 LEHQYAQSYKQVSV---LEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIMSLEDF 135 Query: 418 AAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMT 468 L + + A LE DE E + +D+ ++EL + Sbjct: 136 EQRLNQAIERNAFLESEL----DEKESLLVSVQRLKDEARDLRQELAVRER 182 >3KZ4-A nrPDB Length = 880 Score = 30.9 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 23/119 (19%), Positives = 55/119 (46%), Gaps = 8/119 (6%) Query: 328 KRRETVEREKEQMMREKEELM---LRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQE 384 RRE ++M + +E R+Q ++ K E +++ + +E +K +E Sbjct: 8 ARREANINNNDRMQEKDDEKQDQNNRMQLSDKVLSKKEEVVTDSQEEIKIADEVKKSTKE 67 Query: 385 EAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAE-YTAKIALLEEARRRKEDEV 442 E+++L + L+ KEE +++ +I + E E K+ ++ + +K+ ++ Sbjct: 68 ESKQL----LEVLKTKEEHQKEIQYEILQKTIPTFEPKESILKKLEDIKPEQAKKQTKL 122 >1YIO-A nrPDB Length = 208 Score = 30.9 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 23/69 (33%), Positives = 40/69 (57%), Gaps = 3/69 (4%) Query: 362 ERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAEL 421 E+ L + I++ LQL ER++A+E ++LE ++L +E+ Q + +Q+A EL Sbjct: 109 EQALLDAIEQGLQLNAERRQARETQDQLE-QLFSSLTGREQQVLQLTIRGLMNKQIAGEL 167 Query: 422 --AEYTAKI 428 AE T K+ Sbjct: 168 GIAEVTVKV 176 >3K1J-A nrPDB Length = 604 Score = 30.9 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 28/105 (26%), Positives = 48/105 (45%), Gaps = 15/105 (14%) Query: 288 HELYMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEEL 347 +E+YMR PDTIE ++ Q ++ ++ + E E + RE ++ K L Sbjct: 280 YEVYMRTTMPDTIENRRKLVQFVAQEVKRDGKIPHFTKE--AVEEIVREAQKRAGRKGHL 337 Query: 348 MLRLQDY------------EEKTKKAERE-LSEQIQRALQLEEER 379 LRL+D ++ K ERE + E ++ A LE++ Sbjct: 338 TLRLRDLGGIVRAAGDIAVKKGKKYVEREDVIEAVKMAKPLEKQL 382 >6F1U-X nrPDB Length = 577 Score = 30.9 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 31/169 (18%), Positives = 69/169 (40%), Gaps = 22/169 (13%) Query: 312 EKHQKQLERQQLETEKKRRETVEREKEQMMREK-------------EELMLRLQDYEEKT 358 ++ Q +LERQQL + RE +E + + +L +++ +E Sbjct: 178 KQLQDELERQQLHLREADREKTRAVQELSEQNQRLLDQLSRASEVERQLSMQVHALKEDF 237 Query: 359 KKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIK------ 412 ++ ++ I R L+ E K + LE R++A + +L + V++++ Sbjct: 238 REKNSSTNQHIIRLESLQAEIKMLSDRKRELE-HRLSATLEENDLLQGTVEELQDRVLIL 296 Query: 413 SQEQLAAELAEYTAKIALLEE--ARRRKEDEVEEWQHRAKEAQDDLVKT 459 ++ +L + +++ L E + R+ + +VEE T Sbjct: 297 ERQGHDKDLQLHQSQLELQEVRLSYRQLQGKVEELTEERSLQSSAATST 345 Score = 29.3 bits (64), Expect = 4.8, Method: Composition-based stats. Identities = 27/138 (19%), Positives = 59/138 (42%), Gaps = 8/138 (5%) Query: 334 EREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADR 393 E++ R + L+ R QD + ++ +EL+++++ Q + E +R E E R Sbjct: 110 EKDLVLAARLGKALLERNQDMSRQYEQMHKELTDKLEHLEQEKHELRRRFENREGEWEGR 169 Query: 394 MAALRA-----KEELERQAV---DQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEW 445 ++ L ++ELERQ + + + + + EL+E ++ E ++ Sbjct: 170 VSELETDVKQLQDELERQQLHLREADREKTRAVQELSEQNQRLLDQLSRASEVERQLSMQ 229 Query: 446 QHRAKEAQDDLVKTKEEL 463 H KE + + + Sbjct: 230 VHALKEDFREKNSSTNQH 247 >3DWL-A nrPDB Length = 427 Score = 30.9 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 25/57 (43%), Gaps = 4/57 (7%) Query: 441 EVEEWQHRAKEAQDDLVK----TKEELHLVMTAPPPPPPPVYEPVSYHVQESLQDEG 493 ++E W H + Q L K E+ + ++T PP PP E + + ES G Sbjct: 98 QIENWDHMERFWQQSLFKYLRCEPEDHYFLLTEPPLNPPENRENTAEIMFESFNCAG 154 >4KV9-A nrPDB Length = 412 Score = 30.9 bits (68), Expect = 1.8, Method: Composition-based stats. Identities = 32/152 (21%), Positives = 66/152 (43%), Gaps = 14/152 (9%) Query: 286 GNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKE 345 NH ++R R+ + V + R + R+Q E R+ + ++ ++ Sbjct: 265 ENHCDFVRLREM-LLRVNMEDLRERTHGVHYETYRRQRLIEMGFRDDEKMSLQETYEKRR 323 Query: 346 ELMLR-LQDYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELE 404 EL + LQ EE+ + Q +Q +E+++ +EAER + +L+ E Sbjct: 324 ELQRKELQQKEEEMR----------QMFVQRVKEKEQVLKEAERELQTKFESLKKTHAEE 373 Query: 405 RQAVDQIKSQEQLAAELAEYTAKIALLEEARR 436 ++ + + L E+A + + L E+AR+ Sbjct: 374 KKK--LEEKKRFLEEEIAAFERRKQLAEQARQ 403 Score = 30.5 bits (67), Expect = 2.2, Method: Composition-based stats. Identities = 21/125 (16%), Positives = 52/125 (41%), Gaps = 6/125 (4%) Query: 345 EELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELE 404 E+L R +T + +R I+ + +E+ + +R E R + +EE+ Sbjct: 283 EDLRERTHGVHYETYRRQR----LIEMGFRDDEKMSLQETYEKRRELQRKELQQKEEEMR 338 Query: 405 RQAVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELH 464 + V ++K +EQ+ E E ++ +E ++ + + + ++++ + Sbjct: 339 QMFVQRVKEKEQVLKEAERELQ--TKFESLKKTHAEEKKKLEEKKRFLEEEIAAFERRKQ 396 Query: 465 LVMTA 469 L A Sbjct: 397 LAEQA 401 >5WLZ-C nrPDB Length = 216 Score = 30.1 bits (66), Expect = 2.4, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 42/103 (40%), Gaps = 3/103 (2%) Query: 356 EKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQE 415 EK + + E I AL + Q E E L A R+++ E++ ++ + + Sbjct: 116 EKVENPAEVIRELIDYAL---DRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQ 172 Query: 416 QLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVK 458 L ++ + ++ + + EVEE + A++ K Sbjct: 173 LLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKK 215 >1ZXE-A nrPDB Length = 303 Score = 30.1 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 14/26 (53%), Positives = 19/26 (73%), Gaps = 1/26 (3%) Query: 547 RTHNDIIHNENMRQGRDKY-KTLRQI 571 RT D+IH+EN+ Q RD+Y + RQI Sbjct: 100 RTLYDLIHSENLNQQRDEYWRLFRQI 125 >6OJ5-A nrPDB Length = 887 Score = 30.1 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 15/87 (17%), Positives = 39/87 (44%) Query: 378 ERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARRR 437 ++ A+ E + DRM + + + ++ ++ QL+ ++ ++ + + Sbjct: 4 RKRGARRETNLKQDDRMQEKEENKNVNTNSENKNATKPQLSEKVLSQKEEVITDNQEEIK 63 Query: 438 KEDEVEEWQHRAKEAQDDLVKTKEELH 464 DEV++ + +++KTKEE Sbjct: 64 IADEVKKSNKEESKQLLEVLKTKEEHQ 90 >1YIR-A nrPDB Length = 408 Score = 30.1 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 8/84 (9%) Query: 264 APDFVFYAPRLRINKRILQLCMGNHELYMRRRKP----DTIEVQQMKAQAREEKHQKQLE 319 APDF+ + R N R +Q + N E ++R + P EV + A E +++ + Sbjct: 85 APDFIRFLGLFRFNPRYVQTGIENDEFFLRLKGPWLHVILFEVPLL-AMISEVRNRARYP 143 Query: 320 RQQLETEKKRRETVEREKEQMMRE 343 +E + RE ++ + + + RE Sbjct: 144 AATVE---QARERLQEKFDWLRRE 164 >1SJJ-A nrPDB Length = 863 Score = 30.1 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 40/85 (47%), Gaps = 5/85 (5%) Query: 306 KAQAREEKHQKQLERQQLETEKKRRETV-----EREKEQMMREKEELMLRLQDYEEKTKK 360 + QA E+H +Q + ++L + + V + + E++ R E+ L+D ++ Sbjct: 590 RDQALMEEHARQQQNERLRKQFGAQANVIGPWIQTKMEEIGRISIEMHGTLEDQLNHLRQ 649 Query: 361 AERELSEQIQRALQLEEERKRAQEE 385 E+ + + QLE + ++ QE Sbjct: 650 YEKSIVNYKPKIDQLEGDHQQIQEA 674 >6BJC-T nrPDB Length = 747 Score = 30.1 bits (66), Expect = 2.8, Method: Composition-based stats. Identities = 28/164 (17%), Positives = 63/164 (38%), Gaps = 21/164 (12%) Query: 311 EEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELM-LRLQDYEEKTKKAERELSEQI 369 ++K K E Q+LE K +++E +M ++ EE L L + KK+ ++++ + Sbjct: 203 KQKFLKSTEEQELEKSMK----MQQEVVEMRKKNEEFKKLALAGIGQPVKKSVSQVTKSV 258 Query: 370 QRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAE---YTA 426 + +E K+ + E + E +++ A + + Sbjct: 259 DFHFRTDERIKQHPKNQEEYK-------------EVNFTSELRKHPSSPARVTKGCTIVK 305 Query: 427 KIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAP 470 L + +R ++ V + A++ +D +T HL Sbjct: 306 PFNLSQGKKRTFDETVSTYVPLAQQVEDFHKRTPNRYHLRSKKD 349 >4NBQ-A nrPDB Length = 715 Score = 30.1 bits (66), Expect = 2.8, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 25/57 (43%) Query: 306 KAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAE 362 KA +EK +Q + Q + + ERE E+ + EL + + E + + + Sbjct: 274 KAYQIQEKTARQAQIQAIRDQLLADRAAEREGEENAVNEHELAVIFHELERRIVREQ 330 >2TMA-A nrPDB Length = 284 Score = 30.1 bits (66), Expect = 3.0, Method: Composition-based stats. Identities = 30/159 (18%), Positives = 67/159 (42%), Gaps = 2/159 (1%) Query: 298 DTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEK 357 D + Q K + E++ K E L+ +++ E E++ + L R+Q EE+ Sbjct: 41 DELVSLQKKLKGTEDELDKYSE--ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEE 98 Query: 358 TKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQL 417 +A+ L+ +Q+ + E+ ++ + +E+ E E Q + E Sbjct: 99 LDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDA 158 Query: 418 AAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDL 456 + E K+ ++E R E+ E + + E ++++ Sbjct: 159 DRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEEI 197 >3S84-A nrPDB Length = 273 Score = 30.1 bits (66), Expect = 3.0, Method: Composition-based stats. Identities = 49/243 (20%), Positives = 93/243 (38%), Gaps = 25/243 (10%) Query: 312 EKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQR 371 EK ++++ ++ E + +++ EL RL+ Y ++ + Q Sbjct: 14 EKLKEEIGKELEELRARLLPHANEVSQKIGDNLRELQQRLEPYADQLR---------TQV 64 Query: 372 ALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQ-----EQLAAELAEYTA 426 Q E+ R++ A+R+E + + R D++K++ E+L L Y Sbjct: 65 NTQAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYAD 124 Query: 427 KIALL-----EEARRRK----EDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPV 477 + + EE RR +D E+ H+ + + K EEL ++A Sbjct: 125 EFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQR 184 Query: 478 YEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQRQLLTLSSE 537 P++ V+ +L+ AEL G D + EE R E + L+ + Sbjct: 185 LAPLAEDVRGNLRGNTEGLQKSLAELG--GHLDQQVEEFRRRVEPYGENFNKALVQQMEQ 242 Query: 538 LSQ 540 L Q Sbjct: 243 LRQ 245 >3R2P-A nrPDB Length = 185 Score = 29.7 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 28/124 (22%), Positives = 56/124 (45%), Gaps = 4/124 (3%) Query: 307 AQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELS 366 +Q KQL + L+ T + +EQ+ +E L+ E ++ + Sbjct: 32 SQFEGSALGKQLNLKLLDNWDSVTSTFSKLREQLGPVTQEFWDNLEKETEGLRQEMSKDL 91 Query: 367 EQIQRALQ--LEEERKRAQEEAERLEADRMAALRA-KEELERQAVDQIKSQEQLAAELAE 423 E+++ +Q L++ +K+ QEE E L ++ LRA +E RQ + +++ + E Sbjct: 92 EEVKAKVQPYLDDFQKKWQEEME-LYRQKVEPLRAELQEGARQKLHELQEKLSPLGEEMR 150 Query: 424 YTAK 427 A+ Sbjct: 151 DRAR 154 >3J9M-8 nrPDB Length = 206 Score = 29.7 bits (65), Expect = 3.4, Method: Composition-based stats. Identities = 40/181 (22%), Positives = 69/181 (38%), Gaps = 20/181 (11%) Query: 312 EKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQR 371 E HQ+ E R E + ++K+ ++ +E RL+ K +KA +EL Sbjct: 29 ETHQRASLLSFWELIPMRSEPLRKKKKVDPKKDQEAKERLKRKIRKLEKATQELIPIEDF 88 Query: 372 ALQ---LEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKI 428 L++ R+R Q E E +R A L K L +Q ++ E A + Sbjct: 89 ITPLKFLDKARERPQVELTFEETERRALLLKKWSLYKQ--------QERKMERDTIRAML 140 Query: 429 ALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPP--PPPPPVYEPVSYHVQ 486 +++ +EE Q + + + +K L P PP P Y+P Sbjct: 141 E-------AQQEALEELQLESPKLHAEAIKRDPNLFPFEKEGPHYTPPIPNYQPPEGRYN 193 Query: 487 E 487 + Sbjct: 194 D 194 >4DVY-P nrPDB Length = 876 Score = 29.7 bits (65), Expect = 3.4, Method: Composition-based stats. Identities = 36/222 (16%), Positives = 84/222 (37%), Gaps = 25/222 (11%) Query: 240 FPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDT 299 F ++ N++ FV + ++ K NK I N EL + Sbjct: 543 FNLPDLNNLAIT--SFVRRNLENKLTAKGLSLQE--ANKLIKDFLSSNKELAGK-----A 593 Query: 300 IEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTK 359 + + A+A+ + ++++ Q + EK R+ EKE + ++K Sbjct: 594 LNFNKAVAEAKSTGNYDEVKKAQKDLEKSLRKREHLEKEVEKKL-------------ESK 640 Query: 360 KAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAA 419 + E +A ++E + +A +A + + ++R+ D++ E+++ Sbjct: 641 SGNKNKMEAKAQANSQKDEIFALINKEANRDARAIAYTQNLKGIKRELSDKL---EKISK 697 Query: 420 ELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKE 461 +L +++ + + + + EE K + DL E Sbjct: 698 DLKDFSKSFDEFKNGKNKDFSKAEETLKALKGSVKDLGINPE 739 >5AJ4-Ad nrPDB Length = 177 Score = 29.7 bits (65), Expect = 3.6, Method: Composition-based stats. Identities = 22/112 (19%), Positives = 45/112 (40%) Query: 302 VQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKA 361 + +++ + E + Q ER+ E + RE + + + R E + RL+ + ++ Sbjct: 49 MSEVRKKLHEARAGVQAERKAQEDAAEHRELMAWNQAENQRLHELRLARLRQEALEQERR 108 Query: 362 ERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKS 413 + E + R Q + K + + EA E +A+D KS Sbjct: 109 QAEEAVLQAREAQAWAQLKEQEVLQLQEEAKTFITRENLEARVEEALDSPKS 160 >3JCR-F nrPDB Length = 820 Score = 29.7 bits (65), Expect = 3.8, Method: Composition-based stats. Identities = 29/136 (21%), Positives = 51/136 (37%), Gaps = 7/136 (5%) Query: 332 TVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEA 391 ERE E + R ++E+ R + EE+ KK + + ++ E+ + +E ER E Sbjct: 166 KAEREAEALKRRQQEVEERQRMLEEERKKRK----QFQDLGRKMLED-PQERERRERRER 220 Query: 392 DRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDE--VEEWQHRA 449 ++E RQ + + K + + + E R D V EW Sbjct: 221 MERETNGNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTRHLNDRKFVFEWDASE 280 Query: 450 KEAQDDLVKTKEELHL 465 + D KE + Sbjct: 281 DTSIDYNPLYKERHQV 296 >5JCF-A nrPDB Length = 701 Score = 29.7 bits (65), Expect = 3.9, Method: Composition-based stats. Identities = 36/158 (22%), Positives = 65/158 (41%), Gaps = 7/158 (4%) Query: 312 EKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQR 371 ++H QL+ Q E KK ++ ++ E+M +Q Y + K+E Q Sbjct: 221 KEHASQLKNQVKEPFKKTVIADDKRRDPFRERIIEIMQDIQKYCQLYPKSEFGSQPYEQW 280 Query: 372 ALQLEEERKRAQEEAERLEADRMAALRAKEELER--QAVDQIKSQEQLAAELA-EYTAKI 428 ++ E + ++ ER+ A+ + ++ + VD EL TA+ Sbjct: 281 VIREERRAAKEEKRKERVCAEHLKKYNDALQINDTIRMVDAYNHLNNFYKELKRRKTAES 340 Query: 429 ALLEEARRRKEDEVEEWQHR---AKEAQ-DDLVKTKEE 462 EE K+DE +E+ R AK+ Q +L + E Sbjct: 341 DDDEEPLVSKQDETDEFLMRLFHAKKKQLKELARKPEY 378 >4DVZ-A nrPDB Length = 569 Score = 29.7 bits (65), Expect = 3.9, Method: Composition-based stats. Identities = 36/222 (16%), Positives = 84/222 (37%), Gaps = 25/222 (11%) Query: 240 FPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDT 299 F ++ N++ FV + ++ K NK I N EL + Sbjct: 283 FNLPDLNNLAIT--SFVRRNLENKLTAKGLSLQE--ANKLIKDFLSSNKELAGK-----A 333 Query: 300 IEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTK 359 + + A+A+ + ++++ Q + EK R+ EKE + ++K Sbjct: 334 LNFNKAVAEAKSTGNYDEVKKAQKDLEKSLRKREHLEKEVEKKL-------------ESK 380 Query: 360 KAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAA 419 + E +A ++E + +A +A + + ++R+ D++ E+++ Sbjct: 381 SGNKNKMEAKAQANSQKDEIFALINKEANRDARAIAYTQNLKGIKRELSDKL---EKISK 437 Query: 420 ELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKE 461 +L +++ + + + + EE K + DL E Sbjct: 438 DLKDFSKSFDEFKNGKNKDFSKAEETLKALKGSVKDLGINPE 479 >2NCA-A nrPDB Length = 128 Score = 29.7 bits (65), Expect = 4.0, Method: Composition-based stats. Identities = 19/74 (25%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Query: 377 EERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARR 436 E ++ Q+E E L+ R E +R + +++ E AEL A+ L + R Sbjct: 40 ERMEQFQKEKEELDRGCRECKRKVAECQR-KLKELEVAEGGKAELERLQAEAQQLRKEER 98 Query: 437 RKEDEVEEWQHRAK 450 E ++EE + + K Sbjct: 99 SWEQKLEEMRKKEK 112 >5WLC-LU nrPDB Length = 489 Score = 29.3 bits (64), Expect = 4.5, Method: Composition-based stats. Identities = 27/121 (22%), Positives = 56/121 (46%), Gaps = 8/121 (6%) Query: 329 RRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEEAER 388 R + ER + REK +L +Y+EK K+ R + E I+R + + ++A+ Sbjct: 376 RSKAWERSNVKTTREKNKL-----EYDEKLKERFRHMPE-IKRISR-HRHVPQVIKKAQE 428 Query: 389 LEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEAR-RRKEDEVEEWQH 447 ++ +++++ +E ER+ + + ++ K R RRKED+ + Q Sbjct: 429 IKNIELSSIKRREANERRTRKDMPYISERKKQIVGTVHKYEDSGRDRKRRKEDDKRDTQE 488 Query: 448 R 448 + Sbjct: 489 K 489 >5J1F-A nrPDB Length = 194 Score = 29.3 bits (64), Expect = 4.5, Method: Composition-based stats. Identities = 32/158 (20%), Positives = 62/158 (39%), Gaps = 5/158 (3%) Query: 316 KQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQL 375 ++ E Q + ++ R ++ + E+L+ QD +E+ + + LS +RA + Sbjct: 14 REAEGQLQKLQEALRRKYSCDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAV 73 Query: 376 EEERKRAQEEAERLEADRMAALRAKEELERQ-----AVDQIKSQEQLAAELAEYTAKIAL 430 + AQE RLEA A + +L A ++ QL + T + Sbjct: 74 GSGNQEAQEAVTRLEAQHQALVTLWHQLHVDMKSLLAWQSLRRDVQLIRSWSLATFRTLK 133 Query: 431 LEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMT 468 EE R+ +Q +++QD E+ + Sbjct: 134 PEEQRQALHSLELHYQAFLRDSQDAGGFGPEDRLMAER 171 >5CWS-C nrPDB Length = 208 Score = 29.3 bits (64), Expect = 4.5, Method: Composition-based stats. Identities = 19/73 (26%), Positives = 33/73 (45%) Query: 357 KTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQ 416 K ++E EQ + ++ + E+ ++L A RA E+ERQ + QE+ Sbjct: 11 DLAKYQKEFKEQAAKVMEWDRLLVENGEKIQKLYTSTYEAERASNEIERQLSNVESQQEE 70 Query: 417 LAAELAEYTAKIA 429 L A L Y ++ Sbjct: 71 LTAWLDRYERELD 83 >5OQL-c nrPDB Length = 785 Score = 29.3 bits (64), Expect = 4.7, Method: Composition-based stats. Identities = 44/237 (18%), Positives = 87/237 (36%), Gaps = 23/237 (9%) Query: 306 KAQAREEKHQKQLER-QQLETEKKRRETVEREKEQMMREKEELMLRLQDYE-EKTKKAER 363 + A E + K E+ ++LE E + E ++ L +D E + K Sbjct: 472 RKSAHERRQAKIAEQIRKLEAELVAKRAWTLAGEATAADRPVNSLLGEDMEFDHVGKPVP 531 Query: 364 ELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVD--QIKSQE------ 415 ++E++ +++ +R+ E + + R + R VD K+++ Sbjct: 532 VVTEEVSESIEELIKRRILAGEFDEVLRRRPDMFGNPHGVRRGLVDVEDTKAKQSLAEIY 591 Query: 416 -QLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPP 474 + A + A A ++ +E RR E+E++ D L PP P Sbjct: 592 EEEAVKKANPDAYVSAADEKLRRDEEEIKRMWKEISAKLDALSSWH-----YKPKPPAPT 646 Query: 475 PPVYEPVSYHVQESLQDEGAE--PTGYSAELSSEGIRDDRNEEKRITEAEKNERVQR 529 V V+ E Q A+ G ++ ++ + + + AEK E V + Sbjct: 647 LTVVSDVATVAMEDAQPATAQGVAGGETSMIAPQEVYAPSKDT-----AEKGEVVTK 698 >5A1W-H nrPDB Length = 511 Score = 29.3 bits (64), Expect = 5.3, Method: Composition-based stats. Identities = 19/65 (29%), Positives = 34/65 (52%), Gaps = 8/65 (12%) Query: 298 DTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVERE-KEQMMREKEELMLRLQDYEE 356 + + + Q++ + H++++ R RET ERE K +M R+ +EL +D E Sbjct: 123 ENVNLAQIRTFTEMDSHEEKVFR-------AVRETQEREAKAEMRRKAKELQQARRDAER 175 Query: 357 KTKKA 361 + KKA Sbjct: 176 QGKKA 180 >4XY3-A nrPDB Length = 462 Score = 29.0 bits (63), Expect = 5.4, Method: Composition-based stats. Identities = 30/177 (16%), Positives = 56/177 (31%), Gaps = 25/177 (14%) Query: 323 LETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRA 382 L+ + KR + + E + + + + K +++Q Q QL +R Sbjct: 165 LQGDVKRFRGFDNWEGDAATACEASLDQQRQWILHMAKLSAAMAKQAQYVAQLHVWARRE 224 Query: 383 QEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEV 442 E + LER + +++Q+ AEY R E + Sbjct: 225 HPTYEDIV-----------GLERLYAENPSARDQILPVYAEYQQ----------RSEKVL 263 Query: 443 EEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEPVSYHVQESLQDEGAEPTGY 499 E+ ++A + K + PPPPP + + G P Sbjct: 264 TEYNNKAALEPVNPPKPPP----AIKIDPPPPPQEQGLIPGFLMPPSDGSGVTPGTG 316 >6NEQ-d nrPDB Length = 205 Score = 29.0 bits (63), Expect = 5.7, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 45/112 (40%) Query: 302 VQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKA 361 V +++ + E + ER+ L+ + RE + + + R E M RL+ + ++ Sbjct: 75 VTEVRRKVHEARAGVLAERKALQDAAEHRELMAWNQAENQRLHELRMARLRQEAREQEQW 134 Query: 362 ERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKS 413 + E + + R + K + + +A E +A+D KS Sbjct: 135 QAEEAAREAREAEAWARLKEQEVLQLQEDAKNFITRENLEARVEEALDSPKS 186 >6HA8-V nrPDB Length = 548 Score = 29.0 bits (63), Expect = 6.7, Method: Composition-based stats. Identities = 25/134 (18%), Positives = 54/134 (40%), Gaps = 4/134 (2%) Query: 325 TEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQE 384 ++ + E + ++ K ++ E+K +RE +Q + ++E + Sbjct: 169 LDEAATKIWSLEDQTLIEFKGNYSGYMKFREKKRLTQQREYEKQQKMVERIEAQMNGLAS 228 Query: 385 EAERLEAD--RMAALRAKEELERQAVD-QIKSQEQ-LAAELAEYTAKIALLEEARRRKED 440 +E+ A + + ++ + D QIKS+++ L EL + A+ E R D Sbjct: 229 WSEKAHAQSTKKEGFKEYHRVKAKRTDAQIKSKQKRLEKELEKAKAEPVTPEYTVRFSID 288 Query: 441 EVEEWQHRAKEAQD 454 + R E Q+ Sbjct: 289 TTHKTGKRFLEVQN 302 >1PYS-A nrPDB Length = 350 Score = 29.0 bits (63), Expect = 6.7, Method: Composition-based stats. Identities = 27/103 (26%), Positives = 37/103 (35%), Gaps = 11/103 (10%) Query: 372 ALQLEEERKRAQE---------EAERLEADRMAALRAKEELERQAVD-QIKSQEQLAAEL 421 AL LEE RKR QE A + KE LER+ VD + + L Sbjct: 41 ALPLEERRKRGQELNAIKAALEAALEAREKALEEAALKEALERERVDVSLPGASLFSGGL 100 Query: 422 AEYT-AKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEEL 463 T + L+E R VE + ++ D + E Sbjct: 101 HPITLMERELVEIFRALGYQAVEGPEVESEFFNFDALNIPEHH 143 >1UFA-A nrPDB Length = 520 Score = 28.6 bits (62), Expect = 7.3, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 42/109 (38%), Gaps = 3/109 (2%) Query: 305 MKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERE 364 ++ A+ K + R+ ++ R E + + L + DY EK +AE Sbjct: 372 LRLLAQNPKVRPVTAREAVQGPAVRTALPEGSWGRGGDHRVWLNEKTLDYWEKVYRAEGA 431 Query: 365 LSEQIQRALQLEEERKRAQEEAERLEADR---MAALRAKEELERQAVDQ 410 + E +R + E ++A E LEA + E R+ ++ Sbjct: 432 MREAARRGVLPEGVLRQAMRELLLLEASDWPFLMETGQAEAYARERYEE 480 >6FEC-u nrPDB Length = 636 Score = 28.6 bits (62), Expect = 7.5, Method: Composition-based stats. Identities = 21/121 (17%), Positives = 47/121 (38%), Gaps = 4/121 (3%) Query: 369 IQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKI 428 + A + E +R Q+E E+L R E R+ +S+E E + ++ Sbjct: 392 VDTAAREREVEERLQKEQEKL--QRQLDEPKLERRPRERHPSWRSEETQERERSRTGSES 449 Query: 429 ALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEPVSYHVQES 488 + + + + K +++ + +E+ H + PP P P+ + +E+ Sbjct: 450 SQTGTSTTSSRNA--RRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKEN 507 Query: 489 L 489 Sbjct: 508 A 508 >4L3I-A nrPDB Length = 490 Score = 28.6 bits (62), Expect = 7.8, Method: Composition-based stats. Identities = 28/161 (17%), Positives = 60/161 (37%) Query: 301 EVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKK 360 E Q+++ +KH K+L + E+ +E + + +E L L + + Sbjct: 37 EDQRLQRTEVVKKHIKELLDMMIAEEESLKERLIKSISVCQKELNTLCSELHVEPFQEEG 96 Query: 361 AERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAE 420 L + Q+E RK+ +E + L+ + E L D + E Sbjct: 97 ETTILQLEKDLRTQVELMRKQKKERKQELKLLQEQDQELCEILCMPHYDIDSASVPSLEE 156 Query: 421 LAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKE 461 L ++ + L E + + +E + + ++L T + Sbjct: 157 LNQFRQHVTTLRETKASRREEFVSIKRQIILCMEELDHTPD 197 >5O0Y-A nrPDB Length = 579 Score = 28.6 bits (62), Expect = 7.9, Method: Composition-based stats. Identities = 40/232 (17%), Positives = 86/232 (37%), Gaps = 25/232 (10%) Query: 353 DYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIK 412 D E+K + + L Q++E++K ++ ERL +R + K +E+ +++ Sbjct: 51 DLEKKEGRIDDLLRANCDLRRQIDEQQKMLEKYKERL--NRCVTMSKKLLIEKSKQEKMA 108 Query: 413 SQEQLAAELAEYTAKIALLEEARRRKE-------DEVEEWQHRAKEAQDDLVKTKEELHL 465 +++ + + A ++ + + Q R ++++ ++ L Sbjct: 109 CRDKSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLIKQQERINSQREEI--ERQRKML 166 Query: 466 VMTAPPP--PPPPVYEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEK 523 PP PP ++ E P+ + EL + R+T AE Sbjct: 167 AKRKPPAMGQAPPATNEQKQRKSKTNGAENETPSSGNTELKDTAPALGAHSLLRLTLAEY 226 Query: 524 NERVQ------RQLLTLSSELSQARDENKRTHN------DIIHNENMRQGRD 563 +E+ + L +E+ + +R N IHNE+ Q +D Sbjct: 227 HEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKD 278 >5MDY-7 nrPDB Length = 378 Score = 28.6 bits (62), Expect = 8.7, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 36/89 (40%), Gaps = 2/89 (2%) Query: 326 EKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEE 385 + ++ET +E E+ + + + K + L + LE + + E Sbjct: 31 DIPQKETRLKELERRLEDPSLWND--PEAARKVSQEAARLRRTVDTFRSLESDLQGLLEL 88 Query: 386 AERLEADRMAALRAKEELERQAVDQIKSQ 414 E L A+ AL+ + E + +D++ Q Sbjct: 89 MEELPAEEREALKPELEEAAKKLDELYHQ 117 >2EFK-A nrPDB Length = 301 Score = 28.6 bits (62), Expect = 8.9, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 37/84 (44%), Gaps = 3/84 (3%) Query: 349 LRLQDYEEKTKKAER-ELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELER-- 405 L L Y ++ K+ + E + QLE K+ + + E D A +A + ER Sbjct: 98 LELTKYSQEMKQERKMHFQEGRRAQQQLENGFKQLENSKRKFERDCREAEKAAQTAERLD 157 Query: 406 QAVDQIKSQEQLAAELAEYTAKIA 429 Q ++ K+ + A + A + +A Sbjct: 158 QDINATKADVEKAKQQAHLRSHMA 181 >6FT6-s nrPDB Length = 520 Score = 28.2 bits (61), Expect = 9.3, Method: Composition-based stats. Identities = 29/137 (21%), Positives = 60/137 (43%), Gaps = 5/137 (3%) Query: 310 REEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQI 369 R K Q + +L+ K++ + R+KE+ M +K+ + + +K + Sbjct: 2 RVRKRQSRRTSTKLKEGIKKKASAHRKKEKKMAKKD---VTWRSRSKKDPGIPSNFPYKA 58 Query: 370 QRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQ--IKSQEQLAAELAEYTAK 427 + ++E ++ + EE E + R+ A +A +E A+D+ I+ E A L E + Sbjct: 59 KILEEIEAKKMKDLEERELAKQQRLEARKAAKEQGVDAMDEDMIEDDENGLAALVESAQQ 118 Query: 428 IALLEEARRRKEDEVEE 444 A E + +V + Sbjct: 119 AAAEYEGTPSNDADVRD 135 >1BG7-A nrPDB Length = 176 Score = 28.2 bits (61), Expect = 9.5, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 33/75 (44%) Query: 321 QQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERK 380 + E+ E EK + K + LQD ++ + E +Q ALQLE+ Sbjct: 49 AKFFKEQSHEEREHAEKLMKDQNKRGGRIVLQDVQKPERDEWGNTLEAMQAALQLEKTVN 108 Query: 381 RAQEEAERLEADRMA 395 +A + ++ +D++ Sbjct: 109 QALLDLHKVGSDKVD 123 >2DQ3-A nrPDB Length = 425 Score = 28.2 bits (61), Expect = 9.7, Method: Composition-based stats. Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 9/88 (10%) Query: 294 RRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQD 353 R KPD ++ + A +K L + LE +K+RRE ++R + +L Sbjct: 8 REKPDYVK----ERLATRDKELVSLVDKVLELDKRRREIIKRLEALRSERN-----KLSK 58 Query: 354 YEEKTKKAERELSEQIQRALQLEEERKR 381 K K+ ++ +E R +L+EE R Sbjct: 59 EIGKLKREGKDTTEIQNRVKELKEEIDR 86 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.304 0.126 0.315 Lambda K H 0.267 0.0380 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,808,423 Number of Sequences: 36641 Number of extensions: 761462 Number of successful extensions: 4985 Number of sequences better than 10.0: 309 Number of HSP's better than 10.0 without gapping: 222 Number of HSP's successfully gapped in prelim test: 363 Number of HSP's that attempted gapping in prelim test: 3467 Number of HSP's gapped (non-prelim): 1307 length of query: 586 length of database: 10,336,785 effective HSP length: 102 effective length of query: 484 effective length of database: 6,599,403 effective search space: 3194111052 effective search space used: 3194111052 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.4 bits) S2: 62 (28.6 bits)