BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P15303 (768 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2QTV-A nrPDB 1597 0.0 2NUP-A nrPDB 768 0.0 3EH1-A nrPDB 82 6e-16 2NUP-B nrPDB 73 4e-13 5KYW-B nrPDB 58 2e-08 3EH2-A nrPDB 52 1e-06 1M2V-B nrPDB 49 1e-05 1PD0-A nrPDB 49 1e-05 3TU9-A nrPDB 33 0.67 2HI4-A nrPDB 30 2.7 >2QTV-A nrPDB Length = 772 Score = 1597 bits (4135), Expect = 0.0, Method: Compositional matrix adjust. Identities = 767/767 (100%), Positives = 767/767 (100%) Query: 2 DFETNEDINGVRFTWNVFPSTRSDANSNVVPVGCLYTPLKEYDELNVAPYNPVVCSGPHC 61 DFETNEDINGVRFTWNVFPSTRSDANSNVVPVGCLYTPLKEYDELNVAPYNPVVCSGPHC Sbjct: 6 DFETNEDINGVRFTWNVFPSTRSDANSNVVPVGCLYTPLKEYDELNVAPYNPVVCSGPHC 65 Query: 62 KSILNPYCVIDPRNSSWSCPICNSRNHLPPQYTNLSQENMPLELQSTTIEYITNKPVTVP 121 KSILNPYCVIDPRNSSWSCPICNSRNHLPPQYTNLSQENMPLELQSTTIEYITNKPVTVP Sbjct: 66 KSILNPYCVIDPRNSSWSCPICNSRNHLPPQYTNLSQENMPLELQSTTIEYITNKPVTVP 125 Query: 122 PIFFFVVDLTSETENLDSLKESIITSLSLLPPNALIGLITYGNVVQLHDLSSETIDRCNV 181 PIFFFVVDLTSETENLDSLKESIITSLSLLPPNALIGLITYGNVVQLHDLSSETIDRCNV Sbjct: 126 PIFFFVVDLTSETENLDSLKESIITSLSLLPPNALIGLITYGNVVQLHDLSSETIDRCNV 185 Query: 182 FRGDREYQLEALTEMLTGQKPTGPGGAASHLPNAMNKVTPFSLNRFFLPLEQVEFKLNQL 241 FRGDREYQLEALTEMLTGQKPTGPGGAASHLPNAMNKVTPFSLNRFFLPLEQVEFKLNQL Sbjct: 186 FRGDREYQLEALTEMLTGQKPTGPGGAASHLPNAMNKVTPFSLNRFFLPLEQVEFKLNQL 245 Query: 242 LENLSPDQWSVPAGHRPLRATGSALNIASLLLQGCYKNIPARIILFASGPGTVAPGLIVN 301 LENLSPDQWSVPAGHRPLRATGSALNIASLLLQGCYKNIPARIILFASGPGTVAPGLIVN Sbjct: 246 LENLSPDQWSVPAGHRPLRATGSALNIASLLLQGCYKNIPARIILFASGPGTVAPGLIVN 305 Query: 302 SELKDPLRSHHDIDSDHAQHYKKACKFYNQIAQRVAANGHTVDIFAGCYDQIGMSEMKQL 361 SELKDPLRSHHDIDSDHAQHYKKACKFYNQIAQRVAANGHTVDIFAGCYDQIGMSEMKQL Sbjct: 306 SELKDPLRSHHDIDSDHAQHYKKACKFYNQIAQRVAANGHTVDIFAGCYDQIGMSEMKQL 365 Query: 362 TDSTGGVLLLTDAFSTAIFKQSYLRLFAKDEEGYLKMAFNGNMAVKTSKDLKVQGLIGHA 421 TDSTGGVLLLTDAFSTAIFKQSYLRLFAKDEEGYLKMAFNGNMAVKTSKDLKVQGLIGHA Sbjct: 366 TDSTGGVLLLTDAFSTAIFKQSYLRLFAKDEEGYLKMAFNGNMAVKTSKDLKVQGLIGHA 425 Query: 422 SAVKKTDANNISESEIGIGATSTWKMASLSPYHSYAIFFEIANTAANSNPMMSAPGSADR 481 SAVKKTDANNISESEIGIGATSTWKMASLSPYHSYAIFFEIANTAANSNPMMSAPGSADR Sbjct: 426 SAVKKTDANNISESEIGIGATSTWKMASLSPYHSYAIFFEIANTAANSNPMMSAPGSADR 485 Query: 482 PHLAYTQFITTYQHSSGTNRIRVTTVANQLLPFGTPAIAASFDQEAAAVLMARIAVHKAE 541 PHLAYTQFITTYQHSSGTNRIRVTTVANQLLPFGTPAIAASFDQEAAAVLMARIAVHKAE Sbjct: 486 PHLAYTQFITTYQHSSGTNRIRVTTVANQLLPFGTPAIAASFDQEAAAVLMARIAVHKAE 545 Query: 542 TDDGADVIRWLDRTLIKLCQKYADYNKDDPQSFRLAPNFSLYPQFTYYLRRSQFLSVFNN 601 TDDGADVIRWLDRTLIKLCQKYADYNKDDPQSFRLAPNFSLYPQFTYYLRRSQFLSVFNN Sbjct: 546 TDDGADVIRWLDRTLIKLCQKYADYNKDDPQSFRLAPNFSLYPQFTYYLRRSQFLSVFNN 605 Query: 602 SPDETAFYRHIFTREDTTNSLIMIQPTLTSFSMEDDPQPVLLDSISVKPNTILLLDTFFF 661 SPDETAFYRHIFTREDTTNSLIMIQPTLTSFSMEDDPQPVLLDSISVKPNTILLLDTFFF Sbjct: 606 SPDETAFYRHIFTREDTTNSLIMIQPTLTSFSMEDDPQPVLLDSISVKPNTILLLDTFFF 665 Query: 662 ILIYHGEQIAQWRKAGYQDDPQYADFKALLEEPKLEAAELLVDRFPLPRFIDTEAGGSQA 721 ILIYHGEQIAQWRKAGYQDDPQYADFKALLEEPKLEAAELLVDRFPLPRFIDTEAGGSQA Sbjct: 666 ILIYHGEQIAQWRKAGYQDDPQYADFKALLEEPKLEAAELLVDRFPLPRFIDTEAGGSQA 725 Query: 722 RFLLSKLNPSDNYQDMARGGSTIVLTDDVSLQNFMTHLQQVAVSGQA 768 RFLLSKLNPSDNYQDMARGGSTIVLTDDVSLQNFMTHLQQVAVSGQA Sbjct: 726 RFLLSKLNPSDNYQDMARGGSTIVLTDDVSLQNFMTHLQQVAVSGQA 772 >2NUP-A nrPDB Length = 769 Score = 768 bits (1982), Expect = 0.0, Method: Compositional matrix adjust. Identities = 384/773 (49%), Positives = 515/773 (66%), Gaps = 22/773 (2%) Query: 3 FETNEDINGVRFTWNVFPSTRSDANSNVVPVGCLYTPLKEYDELNVAPYNPVVCSGPHCK 62 + NE+ +GVRF+WNV+PS+R +A VVPV L+TPLKE +L Y PV+CS C+ Sbjct: 12 IQQNEERDGVRFSWNVWPSSRLEATRMVVPVAALFTPLKERPDLPPIQYEPVLCSRTTCR 71 Query: 63 SILNPYCVIDPRNSSWSCPICNSRNHLPPQYTNLSQENMPLEL--QSTTIEYITNKPVTV 120 ++LNP C +D R W+C C RN PP Y +S+ N P EL Q ++IEY+ + + Sbjct: 72 AVLNPLCQVDYRAKLWACNFCYQRNQFPPSYAGISELNQPAELLPQFSSIEYVVLRGPQM 131 Query: 121 PPIFFFVVDLTSETENLDSLKESIITSLSLLPPNALIGLITYGNVVQLHDLSSETIDRCN 180 P IF +VVD E E+L +LKES+ SLSLLPP AL+GLIT+G +VQ+H+L E I + Sbjct: 132 PLIFLYVVDTCMEDEDLQALKESMQMSLSLLPPTALVGLITFGRMVQVHELGCEGISKSY 191 Query: 181 VFRGDREYQLEALTEMLTGQKPTGPGGAASHLPNAMNKVTPFSLNRFFLPLEQVEFKLNQ 240 VFRG ++ + L EML K P A+ P P NRF P+++++ L Sbjct: 192 VFRGTKDLSAKQLQEMLGLSKV--PVTQATRGPQVQQ---PPPSNRFLQPVQKIDMNLTD 246 Query: 241 LLENLSPDQWSVPAGHRPLRATGSALNIASLLLQGCYKNIPARIILFASGPGTVAPGLIV 300 LL L D W VP G RPLR++G AL+IA LL+ + N ARI++F GP T PG++V Sbjct: 247 LLGELQRDPWPVPQGKRPLRSSGVALSIAVGLLECTFPNTGARIMMFIGGPATQGPGMVV 306 Query: 301 NSELKDPLRSHHDIDSDHAQHYKKACKFYNQIAQRVAANGHTVDIFAGCYDQIGMSEMKQ 360 ELK P+RS HDID D+A++ KK K + +A R A GH +DI+A DQ G+ EMK Sbjct: 307 GDELKTPIRSWHDIDKDNAKYVKKGTKHFEALANRAATTGHVIDIYACALDQTGLLEMKC 366 Query: 361 LTDSTGGVLLLTDAFSTAIFKQSYLRLFAKDEEGYLKMAFNGNMAVKTSKDLKVQGLIGH 420 + TGG +++ D+F+T++FKQ++ R+F KD G KM F G + +KTS+++K+ G IG Sbjct: 367 CPNLTGGYMVMGDSFNTSLFKQTFQRVFTKDMHGQFKMGFGGTLEIKTSREIKISGAIGP 426 Query: 421 ASAVKKTDANNISESEIGIGATSTWKMASLSPYHSYAIFFEIANTAANSNPMMSAPGSAD 480 ++ + +SE+EIG G T WK+ LSP + AI+FE+ N ++ P+ A Sbjct: 427 CVSLN-SKGPCVSENEIGTGGTCQWKICGLSPTTTLAIYFEVVNQ--HNAPIPQGGRGA- 482 Query: 481 RPHLAYTQFITTYQHSSGTNRIRVTTVANQLLPFGTPA--IAASFDQEAAAVLMARIAVH 538 QF+T YQHSSG RIRVTT+A T IAASFDQEAAA+LMAR+A++ Sbjct: 483 ------IQFVTQYQHSSGQRRIRVTTIARNWADAQTQIQNIAASFDQEAAAILMARLAIY 536 Query: 539 KAETDDGADVIRWLDRTLIKLCQKYADYNKDDPQSFRLAPNFSLYPQFTYYLRRSQFLSV 598 +AET++G DV+RWLDR LI+LCQK+ +Y+KDDP SFR + FSLYPQF ++LRRS FL V Sbjct: 537 RAETEEGPDVLRWLDRQLIRLCQKFGEYHKDDPSSFRFSETFSLYPQFMFHLRRSSFLQV 596 Query: 599 FNNSPDETAFYRHIFTREDTTNSLIMIQPTLTSFSMEDDPQPVLLDSISVKPNTILLLDT 658 FNNSPDE+++YRH F R+D T SLIMIQP L ++S P+PVLLDS S+ + ILL+DT Sbjct: 597 FNNSPDESSYYRHHFMRQDLTQSLIMIQPILYAYSFSGPPEPVLLDSSSILADRILLMDT 656 Query: 659 FFFILIYHGEQIAQWRKAGYQDDPQYADFKALLEEPKLEAAELLVDRFPLPRFIDTEAGG 718 FF ILIYHGE IAQWRK+GYQD P+Y +F+ LL+ P +A E+L RFP+PR+IDTE GG Sbjct: 657 FFQILIYHGETIAQWRKSGYQDMPEYENFRHLLQAPVDDAQEILHSRFPMPRYIDTEHGG 716 Query: 719 SQARFLLSKLNPSDNYQDMARGG---STIVLTDDVSLQNFMTHLQQVAVSGQA 768 SQARFLLSK+NPS + +M G +LTDDVSLQ FM HL+++AVS A Sbjct: 717 SQARFLLSKVNPSQTHNNMYAWGQESGAPILTDDVSLQVFMDHLKKLAVSSAA 769 >3EH1-A nrPDB Length = 751 Score = 82.4 bits (202), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 134/646 (20%), Positives = 258/646 (39%), Gaps = 108/646 (16%) Query: 10 NGVRFTWNVFPSTRSDANSNVVPVGCLYTPLKEYDELNVAPYNPVV-CSGPHCKSILNPY 68 + R T P T++ N +P+G L P ++ +L V N +V C C++ +NP+ Sbjct: 41 DSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQLPVITSNTIVRCRS--CRTYINPF 98 Query: 69 C-VIDPRNSSWSCPICNSRNHLPPQYT------NLSQENMPLELQSTTIEYITNKPVTV- 120 ID R W C +C N +P ++ + + + E+Q++T+E+I + + Sbjct: 99 VSFIDQRR--WKCNLCYRVNDVPEEFMYNPLTRSYGEPHKRPEVQNSTVEFIASSDYMLR 156 Query: 121 ---PPIFFFVVDLTS---ETENLDSLKESIITSLSLLPPNA--LIGLITYGNVVQLHDLS 172 P ++ FV+D++ E L L +S++ +L LP ++ IG +T+ + + ++L Sbjct: 157 PPQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGDSRTRIGFMTFDSTIHFYNLQ 216 Query: 173 SETIDRCNVFRGDREYQLEALTEMLTGQKPTGPGGAASHLPNAMNKVTPFSLNRFFLPLE 232 G + Q+ ++++ PT P+++ L + E Sbjct: 217 ----------EGLSQPQMLIVSDIDDVFLPT---------PDSL-------LVNLYESKE 250 Query: 233 QVEFKLNQLLENLSPDQWSVPAGHRPLRATGSALNIASLLLQGCYKNIP---ARIILFAS 289 ++ LN L P R T SAL A LQ +K + R+ +F + Sbjct: 251 LIKDLLNAL-----------PNMFTNTRETHSALGPA---LQAAFKLMSPTGGRVSVFQT 296 Query: 290 GPGTVAPGLIVNSELKDPLRSHHDIDSDHAQHYKKACKFYNQIAQRVAANGHTVDIFAGC 349 ++ GL+ + E DP + + QH A FY ++A + VD+F Sbjct: 297 QLPSLGAGLLQSRE--DP---NQRSSTKVVQHLGPATDFYKKLALDCSGQQTAVDLFLLS 351 Query: 350 YDQIGMSEMKQLTDSTGGVLLLTDAFSTAIFKQSYLRLFAKDEEGYL--KMAFNGNMAVK 407 ++ + ++ + G + +F S KD + YL K+ F M ++ Sbjct: 352 SQYSDLASLACMSKYSAGCIYYYPSFHYT-HNPSQAEKLQKDLKRYLTRKIGFEAVMRIR 410 Query: 408 TSKDLKVQGLIGHASAVKKTDANNISESEIGIGATSTWKMASLSPYHSYAIFFEIANTAA 467 +K L + G+ + +T +A+++P +A+ I + Sbjct: 411 CTKGLSMHTFHGN----------------FFVRSTDLLSLANINPDAGFAVQLSIEESLT 454 Query: 468 NSNPMMSAPGSADRPHLAYTQFITTYQHSSGTNRIRVTTVANQLLPFGTPA--IAASFDQ 525 +++ L Q Y S G RIRV T+ LP + + A D Sbjct: 455 DTS-------------LVCFQTALLYTSSKGERRIRVHTLC---LPVVSSLADVYAGVDV 498 Query: 526 EAAAVLMARIAVHKAETDDGADVIRWLDRTLIKLCQKYADYNKDDPQSFRLAP-NFSLYP 584 +AA L+A +AV ++ + +D L ++ Y + S +AP + L+P Sbjct: 499 QAAICLLANMAVDRSVSSSLSDARDALVNAVVDSLSAYGSTVSNLQHSALMAPSSLKLFP 558 Query: 585 QFTY-YLRRSQFLSVFNNSPDETAFYRHIFTREDTTNSLIMIQPTL 629 + L++ F + + D+ + + + + MI P L Sbjct: 559 LYVLALLKQKAFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNL 604 >2NUP-B nrPDB Length = 753 Score = 73.2 bits (178), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 135/624 (21%), Positives = 237/624 (37%), Gaps = 113/624 (18%) Query: 13 RFTWNVFPSTRSDANSNVVPVGCLYTPLKEYDELNVAPYNPVV-CSGPHCKSILNPYC-V 70 R T P T++ N +P+G L P K+ +L V + +V C C++ +NP+ Sbjct: 47 RCTLTSIPQTQALLNKAKLPLGLLLHPFKDLVQLPVVTSSTIVRCRS--CRTYINPFVSF 104 Query: 71 IDPRNSSWSCPICNSRNHLPPQ--YTNLSQ-----ENMPLELQSTTIEYITNKPVTV--- 120 +D R W C +C N +P + Y L++ P E+Q+ TIE++ + Sbjct: 105 LDQRR--WKCNLCYRVNDVPEEFLYNPLTRVYGEPHRRP-EVQNATIEFMAPSEYMLRPP 161 Query: 121 -PPIFFFVVDLTS---ETENLDSLKESIITSLSLLPPNAL--IGLITYGNVVQLHDLSSE 174 PP++ FV D++ ET L+S+ +S++ +L LLP N IG IT+ + + + L Sbjct: 162 QPPVYLFVFDVSHNAVETGYLNSVCQSLLDNLDLLPGNTRTKIGFITFDSTIHFYGLQES 221 Query: 175 TIDRCNVFRGDREYQLEALTEMLTGQKPTGPGGAASHLPNAMNKVTPFSLNRFFLPL-EQ 233 + D E F+P+ E Sbjct: 222 LSQPQMLIVSDIE--------------------------------------DVFIPMPEN 243 Query: 234 VEFKLNQLLENLSPDQWSVPAGHRPLRATGSALNIASLLLQGCYKNIP---ARIILFASG 290 + LN+ E + ++P T SAL A LQ +K + R+ +F + Sbjct: 244 LLVNLNESKELVQDLLKTLPQMFTKTLETQSALGPA---LQAAFKLMSPTGGRMSVFQTQ 300 Query: 291 PGTVAPGLIVNSELKDPLRSHHDIDSDHAQHYKKACKFYNQIAQRVAANGHTVDIFAGCY 350 T+ G + E + S DI H + FY ++A + VD+F Sbjct: 301 LPTLGVGALKPREEPNHRSSAKDI------HMTPSTDFYKKLALDCSGQQVAVDLFLLSG 354 Query: 351 DQIGMSEMKQLTDSTGGVLLLTDAFSTAIFKQSYLRLFAKDEEGYL--KMAFNGNMAVKT 408 ++ + ++ + G + ++ ++ K+ + YL K+ F M ++ Sbjct: 355 QYSDLASLGCISRYSAGSVYYYPSYHHQ-HNPVQVQKLQKELQRYLTRKIGFEAVMRIRC 413 Query: 409 SKDLKVQGLIGHASAVKKTDANNISESEIGIGATSTWKMASLSPYHSYAIFFEIANTAAN 468 +K L + G+ + +T + +++P YA+ Sbjct: 414 TKGLSIHTFHGN----------------FFVRSTDLLSLPNVNPDAGYAV---------- 447 Query: 469 SNPMMSAPGSADRPHLAYTQFITTYQHSSGTNRIRVTTVANQLLPFGTPA--IAASFDQE 526 MS S L Q Y S G RIRV T+ LP + + D + Sbjct: 448 ---QMSVEESLTDTQLVSFQSALLYTSSKGERRIRVHTLC---LPVVSTLNDVFLGADVQ 501 Query: 527 AAAVLMARIAVHKAETDDGADVIRWLDRTLIKLCQKYADYNKDDPQSFRLAP-NFSLYPQ 585 A + L+A +AV ++ T +D L +I Y + Q + P + L+P Sbjct: 502 AISGLLANMAVDRSMTASLSDARDALVNAVIDSLSAYRSSVLSNQQPGLMVPFSLRLFPL 561 Query: 586 FTY-YLRRSQFLSVFNNSPDETAF 608 F L++ F + N DE F Sbjct: 562 FVLALLKQKSFQTGTNARLDERIF 585 >5KYW-B nrPDB Length = 770 Score = 58.2 bits (139), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 93/452 (20%), Positives = 171/452 (37%), Gaps = 81/452 (17%) Query: 12 VRFTWNVFPSTRSDANSNVVPVGCLYTPLKEYDE-------LNVAPYNPVVCSGPHCKSI 64 +R T FP T A +P+ + P +N PV C+ CK+ Sbjct: 50 IRCTTYCFPCTSDMAKQAQIPLAAVIKPFATIPSNESPLYLVNHGESGPVRCN--RCKAY 107 Query: 65 LNPYCVIDPRNSSWSCPICNSRNHLPPQY--------TNLSQENMPLELQSTTIEYIT-- 114 + P+ + C CN N +PP Y L P EL + EY+ Sbjct: 108 MCPFMQFIEGGRRYQCGFCNCVNDVPPFYFQHLDHIGRRLDHYEKP-ELSLGSYEYVATL 166 Query: 115 -----NKPVTVPPIFFFVVDLT-SETEN--LDSLKESIITSLSLLPPNA-------LIGL 159 +KP PP F F++D++ S +N + + E + T L +P +G Sbjct: 167 DYCRKSKPPN-PPAFIFMIDVSYSNIKNGLVKLICEELKTMLEKIPKEEQEETSAIRVGF 225 Query: 160 ITYGNVVQLHDLSSETIDRCNVFRGDREYQLEALTEMLTGQKPTGPGGAASHLPNAMNKV 219 ITY V+ ++ S + Q+ +T+ + +V Sbjct: 226 ITYNKVLHFFNVKSNL----------AQPQMMVVTD--------------------VGEV 255 Query: 220 TPFSLNRFFLPLEQVEFKLNQLLENLSPDQWSVPAGHRPLRATGSALNIASLLLQGCYKN 279 L+ F + ++ + ++ LL+ + PD ++ + + A + +L C Sbjct: 256 FVPLLDGFLVNYQESQSVIHNLLDQI-PDMFADSNENETVFAPVIQAGMEALKAADC--- 311 Query: 280 IPARIILFASG-PGTVAPGLIVNSELKDPLRSHHDIDSDHAQ-HYKKACKFYNQIAQRVA 337 P ++ +F S P APG + N + K +++D + ++ Y+ +A+ Sbjct: 312 -PGKLFIFHSSLPTAEAPGKLKNRDDKKL------VNTDKEKILFQPQTNVYDSLAKDCV 364 Query: 338 ANGHTVDIFAGCYDQIGMSEMKQLTDSTGGVLLLTDAFSTAIFKQSYLRLFAKDEEGYLK 397 A+G +V +F + ++ + + TGG L + F + +Q +L D E K Sbjct: 365 AHGCSVTLFLFPSQYVDVASLGLVPQLTGGTLYKYNNFQMHLDRQQFLNDLRNDIEK--K 422 Query: 398 MAFNGNMAVKTSKDLKVQGLIGHASAVKKTDA 429 + F+ M V+TS + G TD Sbjct: 423 IGFDAIMRVRTSTGFRATDFFGGILMNNTTDV 454 >3EH2-A nrPDB Length = 766 Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 90/462 (19%), Positives = 165/462 (35%), Gaps = 101/462 (21%) Query: 12 VRFTWNVFPSTRSDANSNVVPVGCLYTPLKEYDELNVAPY-------NPVVCSGPHCKSI 64 +R T P T A VP+ + PL +PY P+ C+ CK+ Sbjct: 46 IRCTSYNIPCTSDMAKQAQVPLAAVIKPLARLPPEEASPYVVDHGESGPLRCN--RCKAY 103 Query: 65 LNPYCVIDPRNSSWSCPICNSRNHLPPQY--------TNLSQENMP-LELQS----TTIE 111 + P+ + C C+ N +PPQY + + P L L S T++ Sbjct: 104 MCPFMQFIEGGRRFQCCFCSCINDVPPQYFQHLDHTGKRVDAYDRPELSLGSYEFLATVD 163 Query: 112 YITNKPVTVPPIFFFVVDLTS---ETENLDSLKESIITSLSLLPPNA-------LIGLIT 161 Y N PP F F++D++ T + L E + + L LP +G +T Sbjct: 164 YCKNNKFPSPPAFIFMIDVSYNAIRTGLVRLLCEELKSLLDFLPREGGAEESAIRVGFVT 223 Query: 162 YGNVVQLHDLSSETIDRCNVFRGDREYQLEALTEMLTGQKPTGPGGAASHLPNAMNKVTP 221 Y V+ +++ S A +M+ + + + P Sbjct: 224 YNKVLHFYNVKSSL----------------AQPQMMV-------------VSDVADMFVP 254 Query: 222 FSLNRFFLPLEQVEFKLNQLLENLSPDQWS------------VPAGHRPLRATGSALNIA 269 L+ F + + + + LL+ + P+ ++ + AG L+A A Sbjct: 255 L-LDGFLVNVNESRAVITSLLDQI-PEMFADTRETETVFVPVIQAGMEALKAAECA---- 308 Query: 270 SLLLQGCYKNIPARIILF-ASGPGTVAPGLIVNSELKDPLRSHHDIDSDHAQH-YKKACK 327 ++ LF S P APG + N + I++D + ++ Sbjct: 309 ------------GKLFLFHTSLPIAEAPGKLKNRD------DRKLINTDKEKTLFQPQTG 350 Query: 328 FYNQIAQRVAANGHTVDIFAGCYDQIGMSEMKQLTDSTGGVLLLTDAFSTAIFKQSYLRL 387 Y +A+ A G VD+F + ++ + + TGG + +F ++ +L Sbjct: 351 AYQTLAKECVAQGCCVDLFLFPNQYVDVATLSVVPQLTGGSVYKYASFQVENDQERFLSD 410 Query: 388 FAKDEEGYLKMAFNGNMAVKTSKDLKVQGLIGHASAVKKTDA 429 +D + + F+ M V+TS ++ G TD Sbjct: 411 LRRDVQKV--VGFDAVMRVRTSTGIRAVDFFGAFYMSNTTDV 450 >1M2V-B nrPDB Length = 926 Score = 48.5 bits (114), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 38/157 (24%), Positives = 68/157 (43%), Gaps = 14/157 (8%) Query: 5 TNEDINGVRFTWNVFPSTRSDANSNVVPVGCLYTPLKE-YDELNVAPYNP--VVCSGPHC 61 +N + +R T N P S + +P G + P + YD+++ P N ++ C Sbjct: 175 SNASPDYIRSTLNAVPKNSSLLKKSKLPFGLVIRPYQHLYDDIDPPPLNEDGLIVRCRRC 234 Query: 62 KSILNPYCVIDPRNSSWSCPICNSRNHLPPQYTNLSQENMPL------ELQSTTIEYITN 115 +S +NP+ + W C C N +P Q + S N P E++ +EY+ Sbjct: 235 RSYMNPFVTFIEQGRRWRCNFCRLANDVPMQ-MDQSDPNDPKSRYDRNEIKCAVMEYMAP 293 Query: 116 KPVTV----PPIFFFVVDLTSETENLDSLKESIITSL 148 K T+ P + F++D++ + L +I T L Sbjct: 294 KEYTLRQPPPATYCFLIDVSQSSIKSGLLATTINTLL 330 >1PD0-A nrPDB Length = 810 Score = 48.5 bits (114), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 33/136 (24%), Positives = 60/136 (44%), Gaps = 14/136 (10%) Query: 12 VRFTWNVFPSTRSDANSNVVPVGCLYTPLKE-YDELNVAPYNP--VVCSGPHCKSILNPY 68 +R T N P S + +P G + P + YD+++ P N ++ C+S +NP+ Sbjct: 66 IRSTLNAVPKNSSLLKKSKLPFGLVIRPYQHLYDDIDPPPLNEDGLIVRCRRCRSYMNPF 125 Query: 69 CVIDPRNSSWSCPICNSRNHLPPQYTNLSQENMPL------ELQSTTIEYITNKPVTV-- 120 + W C C N +P Q + S N P E++ +EY+ K T+ Sbjct: 126 VTFIEQGRRWRCNFCRLANDVPMQ-MDQSDPNDPKSRYDRNEIKCAVMEYMAPKEYTLRQ 184 Query: 121 --PPIFFFVVDLTSET 134 P + F++D++ + Sbjct: 185 PPPATYCFLIDVSQSS 200 >3TU9-A nrPDB Length = 363 Score = 32.7 bits (73), Expect = 0.67, Method: Compositional matrix adjust. Identities = 30/96 (31%), Positives = 42/96 (43%), Gaps = 6/96 (6%) Query: 119 TVPPIFFFVVDLTS-ETENLDSLKESIITSLSLLPPNALIGLITYGNVVQLHDLSSETID 177 TVPP V L+ ++E S+ + I LL P AL +YG +Q L + Sbjct: 259 TVPPAVTGVTFLSGGQSEEEASINLNAINKCPLLKPWALT--FSYGRALQASALKAWGGK 316 Query: 178 RCNVFRGDREYQLEALTEMLTGQ---KPTGPGGAAS 210 + N+ EY AL L Q P+G GAA+ Sbjct: 317 KENLKAAQEEYVKRALANSLACQGKYTPSGQAGAAA 352 >2HI4-A nrPDB Length = 495 Score = 30.4 bits (67), Expect = 2.7, Method: Compositional matrix adjust. Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 16/82 (19%) Query: 212 LPNAMNKVTPFSLNRFFLPLEQVEFKLNQLLENLSPDQWSVPAGHRPLR---ATGSALNI 268 +P++ + T +LN F++P + F +NQ N P+ W P+ RP R A G+A+N Sbjct: 362 IPHSTTRDT--TLNGFYIPKKCCVF-VNQWQVNHDPELWEDPSEFRPERFLTADGTAIN- 417 Query: 269 ASLLLQGCYKNIPARIILFASG 290 K + +++LF G Sbjct: 418 ---------KPLSEKMMLFGMG 430 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2QTV-A nrPDB 1128 0.0 2NUP-A nrPDB 1079 0.0 3EH1-A nrPDB 611 e-175 2NUP-B nrPDB 591 e-169 3EH2-A nrPDB 461 e-130 5KYW-B nrPDB 459 e-129 1PD0-A nrPDB 330 1e-90 1M2V-B nrPDB 324 1e-88 Sequences not found previously or not previously below threshold: 3CZE-A nrPDB 30 3.5 1SKZ-A nrPDB 30 4.2 3L5K-A nrPDB 29 7.0 CONVERGED! >2QTV-A nrPDB Length = 772 Score = 1128 bits (2917), Expect = 0.0, Method: Composition-based stats. Identities = 767/767 (100%), Positives = 767/767 (100%) Query: 2 DFETNEDINGVRFTWNVFPSTRSDANSNVVPVGCLYTPLKEYDELNVAPYNPVVCSGPHC 61 DFETNEDINGVRFTWNVFPSTRSDANSNVVPVGCLYTPLKEYDELNVAPYNPVVCSGPHC Sbjct: 6 DFETNEDINGVRFTWNVFPSTRSDANSNVVPVGCLYTPLKEYDELNVAPYNPVVCSGPHC 65 Query: 62 KSILNPYCVIDPRNSSWSCPICNSRNHLPPQYTNLSQENMPLELQSTTIEYITNKPVTVP 121 KSILNPYCVIDPRNSSWSCPICNSRNHLPPQYTNLSQENMPLELQSTTIEYITNKPVTVP Sbjct: 66 KSILNPYCVIDPRNSSWSCPICNSRNHLPPQYTNLSQENMPLELQSTTIEYITNKPVTVP 125 Query: 122 PIFFFVVDLTSETENLDSLKESIITSLSLLPPNALIGLITYGNVVQLHDLSSETIDRCNV 181 PIFFFVVDLTSETENLDSLKESIITSLSLLPPNALIGLITYGNVVQLHDLSSETIDRCNV Sbjct: 126 PIFFFVVDLTSETENLDSLKESIITSLSLLPPNALIGLITYGNVVQLHDLSSETIDRCNV 185 Query: 182 FRGDREYQLEALTEMLTGQKPTGPGGAASHLPNAMNKVTPFSLNRFFLPLEQVEFKLNQL 241 FRGDREYQLEALTEMLTGQKPTGPGGAASHLPNAMNKVTPFSLNRFFLPLEQVEFKLNQL Sbjct: 186 FRGDREYQLEALTEMLTGQKPTGPGGAASHLPNAMNKVTPFSLNRFFLPLEQVEFKLNQL 245 Query: 242 LENLSPDQWSVPAGHRPLRATGSALNIASLLLQGCYKNIPARIILFASGPGTVAPGLIVN 301 LENLSPDQWSVPAGHRPLRATGSALNIASLLLQGCYKNIPARIILFASGPGTVAPGLIVN Sbjct: 246 LENLSPDQWSVPAGHRPLRATGSALNIASLLLQGCYKNIPARIILFASGPGTVAPGLIVN 305 Query: 302 SELKDPLRSHHDIDSDHAQHYKKACKFYNQIAQRVAANGHTVDIFAGCYDQIGMSEMKQL 361 SELKDPLRSHHDIDSDHAQHYKKACKFYNQIAQRVAANGHTVDIFAGCYDQIGMSEMKQL Sbjct: 306 SELKDPLRSHHDIDSDHAQHYKKACKFYNQIAQRVAANGHTVDIFAGCYDQIGMSEMKQL 365 Query: 362 TDSTGGVLLLTDAFSTAIFKQSYLRLFAKDEEGYLKMAFNGNMAVKTSKDLKVQGLIGHA 421 TDSTGGVLLLTDAFSTAIFKQSYLRLFAKDEEGYLKMAFNGNMAVKTSKDLKVQGLIGHA Sbjct: 366 TDSTGGVLLLTDAFSTAIFKQSYLRLFAKDEEGYLKMAFNGNMAVKTSKDLKVQGLIGHA 425 Query: 422 SAVKKTDANNISESEIGIGATSTWKMASLSPYHSYAIFFEIANTAANSNPMMSAPGSADR 481 SAVKKTDANNISESEIGIGATSTWKMASLSPYHSYAIFFEIANTAANSNPMMSAPGSADR Sbjct: 426 SAVKKTDANNISESEIGIGATSTWKMASLSPYHSYAIFFEIANTAANSNPMMSAPGSADR 485 Query: 482 PHLAYTQFITTYQHSSGTNRIRVTTVANQLLPFGTPAIAASFDQEAAAVLMARIAVHKAE 541 PHLAYTQFITTYQHSSGTNRIRVTTVANQLLPFGTPAIAASFDQEAAAVLMARIAVHKAE Sbjct: 486 PHLAYTQFITTYQHSSGTNRIRVTTVANQLLPFGTPAIAASFDQEAAAVLMARIAVHKAE 545 Query: 542 TDDGADVIRWLDRTLIKLCQKYADYNKDDPQSFRLAPNFSLYPQFTYYLRRSQFLSVFNN 601 TDDGADVIRWLDRTLIKLCQKYADYNKDDPQSFRLAPNFSLYPQFTYYLRRSQFLSVFNN Sbjct: 546 TDDGADVIRWLDRTLIKLCQKYADYNKDDPQSFRLAPNFSLYPQFTYYLRRSQFLSVFNN 605 Query: 602 SPDETAFYRHIFTREDTTNSLIMIQPTLTSFSMEDDPQPVLLDSISVKPNTILLLDTFFF 661 SPDETAFYRHIFTREDTTNSLIMIQPTLTSFSMEDDPQPVLLDSISVKPNTILLLDTFFF Sbjct: 606 SPDETAFYRHIFTREDTTNSLIMIQPTLTSFSMEDDPQPVLLDSISVKPNTILLLDTFFF 665 Query: 662 ILIYHGEQIAQWRKAGYQDDPQYADFKALLEEPKLEAAELLVDRFPLPRFIDTEAGGSQA 721 ILIYHGEQIAQWRKAGYQDDPQYADFKALLEEPKLEAAELLVDRFPLPRFIDTEAGGSQA Sbjct: 666 ILIYHGEQIAQWRKAGYQDDPQYADFKALLEEPKLEAAELLVDRFPLPRFIDTEAGGSQA 725 Query: 722 RFLLSKLNPSDNYQDMARGGSTIVLTDDVSLQNFMTHLQQVAVSGQA 768 RFLLSKLNPSDNYQDMARGGSTIVLTDDVSLQNFMTHLQQVAVSGQA Sbjct: 726 RFLLSKLNPSDNYQDMARGGSTIVLTDDVSLQNFMTHLQQVAVSGQA 772 >2NUP-A nrPDB Length = 769 Score = 1079 bits (2789), Expect = 0.0, Method: Composition-based stats. Identities = 384/773 (49%), Positives = 515/773 (66%), Gaps = 22/773 (2%) Query: 3 FETNEDINGVRFTWNVFPSTRSDANSNVVPVGCLYTPLKEYDELNVAPYNPVVCSGPHCK 62 + NE+ +GVRF+WNV+PS+R +A VVPV L+TPLKE +L Y PV+CS C+ Sbjct: 12 IQQNEERDGVRFSWNVWPSSRLEATRMVVPVAALFTPLKERPDLPPIQYEPVLCSRTTCR 71 Query: 63 SILNPYCVIDPRNSSWSCPICNSRNHLPPQYTNLSQENMPLEL--QSTTIEYITNKPVTV 120 ++LNP C +D R W+C C RN PP Y +S+ N P EL Q ++IEY+ + + Sbjct: 72 AVLNPLCQVDYRAKLWACNFCYQRNQFPPSYAGISELNQPAELLPQFSSIEYVVLRGPQM 131 Query: 121 PPIFFFVVDLTSETENLDSLKESIITSLSLLPPNALIGLITYGNVVQLHDLSSETIDRCN 180 P IF +VVD E E+L +LKES+ SLSLLPP AL+GLIT+G +VQ+H+L E I + Sbjct: 132 PLIFLYVVDTCMEDEDLQALKESMQMSLSLLPPTALVGLITFGRMVQVHELGCEGISKSY 191 Query: 181 VFRGDREYQLEALTEMLTGQKPTGPGGAASHLPNAMNKVTPFSLNRFFLPLEQVEFKLNQ 240 VFRG ++ + L EML K P A+ P P NRF P+++++ L Sbjct: 192 VFRGTKDLSAKQLQEMLGLSKV--PVTQATRGPQVQQ---PPPSNRFLQPVQKIDMNLTD 246 Query: 241 LLENLSPDQWSVPAGHRPLRATGSALNIASLLLQGCYKNIPARIILFASGPGTVAPGLIV 300 LL L D W VP G RPLR++G AL+IA LL+ + N ARI++F GP T PG++V Sbjct: 247 LLGELQRDPWPVPQGKRPLRSSGVALSIAVGLLECTFPNTGARIMMFIGGPATQGPGMVV 306 Query: 301 NSELKDPLRSHHDIDSDHAQHYKKACKFYNQIAQRVAANGHTVDIFAGCYDQIGMSEMKQ 360 ELK P+RS HDID D+A++ KK K + +A R A GH +DI+A DQ G+ EMK Sbjct: 307 GDELKTPIRSWHDIDKDNAKYVKKGTKHFEALANRAATTGHVIDIYACALDQTGLLEMKC 366 Query: 361 LTDSTGGVLLLTDAFSTAIFKQSYLRLFAKDEEGYLKMAFNGNMAVKTSKDLKVQGLIGH 420 + TGG +++ D+F+T++FKQ++ R+F KD G KM F G + +KTS+++K+ G IG Sbjct: 367 CPNLTGGYMVMGDSFNTSLFKQTFQRVFTKDMHGQFKMGFGGTLEIKTSREIKISGAIGP 426 Query: 421 ASAVKKTDANNISESEIGIGATSTWKMASLSPYHSYAIFFEIANTAANSNPMMSAPGSAD 480 ++ + +SE+EIG G T WK+ LSP + AI+FE+ N ++ P+ A Sbjct: 427 CVSLN-SKGPCVSENEIGTGGTCQWKICGLSPTTTLAIYFEVVNQ--HNAPIPQGGRGA- 482 Query: 481 RPHLAYTQFITTYQHSSGTNRIRVTTVANQLLPFGTPA--IAASFDQEAAAVLMARIAVH 538 QF+T YQHSSG RIRVTT+A T IAASFDQEAAA+LMAR+A++ Sbjct: 483 ------IQFVTQYQHSSGQRRIRVTTIARNWADAQTQIQNIAASFDQEAAAILMARLAIY 536 Query: 539 KAETDDGADVIRWLDRTLIKLCQKYADYNKDDPQSFRLAPNFSLYPQFTYYLRRSQFLSV 598 +AET++G DV+RWLDR LI+LCQK+ +Y+KDDP SFR + FSLYPQF ++LRRS FL V Sbjct: 537 RAETEEGPDVLRWLDRQLIRLCQKFGEYHKDDPSSFRFSETFSLYPQFMFHLRRSSFLQV 596 Query: 599 FNNSPDETAFYRHIFTREDTTNSLIMIQPTLTSFSMEDDPQPVLLDSISVKPNTILLLDT 658 FNNSPDE+++YRH F R+D T SLIMIQP L ++S P+PVLLDS S+ + ILL+DT Sbjct: 597 FNNSPDESSYYRHHFMRQDLTQSLIMIQPILYAYSFSGPPEPVLLDSSSILADRILLMDT 656 Query: 659 FFFILIYHGEQIAQWRKAGYQDDPQYADFKALLEEPKLEAAELLVDRFPLPRFIDTEAGG 718 FF ILIYHGE IAQWRK+GYQD P+Y +F+ LL+ P +A E+L RFP+PR+IDTE GG Sbjct: 657 FFQILIYHGETIAQWRKSGYQDMPEYENFRHLLQAPVDDAQEILHSRFPMPRYIDTEHGG 716 Query: 719 SQARFLLSKLNPSDNYQDMARGG---STIVLTDDVSLQNFMTHLQQVAVSGQA 768 SQARFLLSK+NPS + +M G +LTDDVSLQ FM HL+++AVS A Sbjct: 717 SQARFLLSKVNPSQTHNNMYAWGQESGAPILTDDVSLQVFMDHLKKLAVSSAA 769 >3EH1-A nrPDB Length = 751 Score = 611 bits (1575), Expect = e-175, Method: Composition-based stats. Identities = 129/649 (19%), Positives = 254/649 (39%), Gaps = 104/649 (16%) Query: 6 NEDINGVRFTWNVFPSTRSDANSNVVPVGCLYTPLKEYDELNVAPYNPVVCSGPHCKSIL 65 N + R T P T++ N +P+G L P ++ +L V N +V C++ + Sbjct: 37 NCSPDSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQLPVITSNTIV-RCRSCRTYI 95 Query: 66 NPYCVIDPRNSSWSCPICNSRNHLPPQYT------NLSQENMPLELQSTTIEYITNKPVT 119 NP+ + W C +C N +P ++ + + + E+Q++T+E+I + Sbjct: 96 NPFVSFIDQ-RRWKCNLCYRVNDVPEEFMYNPLTRSYGEPHKRPEVQNSTVEFIASSDYM 154 Query: 120 V----PPIFFFVVDLTS---ETENLDSLKESIITSLSLLPPNAL--IGLITYGNVVQLHD 170 + P ++ FV+D++ E L L +S++ +L LP ++ IG +T+ + + ++ Sbjct: 155 LRPPQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGDSRTRIGFMTFDSTIHFYN 214 Query: 171 LSSETIDRCNVFRGDREYQLEALTEMLTGQKPTGPGGAASHLPNAMNKVTPFSLNRFFLP 230 L G + Q+ ++++ PT P+++ L + Sbjct: 215 LQ----------EGLSQPQMLIVSDIDDVFLPT---------PDSL-------LVNLYES 248 Query: 231 LEQVEFKLNQLLENLSPDQWSVPAGHRPLRATGSALNIASLLLQGCYKNI---PARIILF 287 E ++ LN L P R T SAL A LQ +K + R+ +F Sbjct: 249 KELIKDLLNAL-----------PNMFTNTRETHSALGPA---LQAAFKLMSPTGGRVSVF 294 Query: 288 ASGPGTVAPGLIVNSELKDPLRSHHDIDSDHAQHYKKACKFYNQIAQRVAANGHTVDIFA 347 + ++ GL+ + E + + QH A FY ++A + VD+F Sbjct: 295 QTQLPSLGAGLLQSREDPN-----QRSSTKVVQHLGPATDFYKKLALDCSGQQTAVDLFL 349 Query: 348 GCYDQIGMSEMKQLTDSTGGVLLLTDAFSTAIFKQSYLRLFAKDEEGYL--KMAFNGNMA 405 ++ + ++ + G + +F S KD + YL K+ F M Sbjct: 350 LSSQYSDLASLACMSKYSAGCIYYYPSFHYT-HNPSQAEKLQKDLKRYLTRKIGFEAVMR 408 Query: 406 VKTSKDLKVQGLIGHASAVKKTDANNISESEIGIGATSTWKMASLSPYHSYAIFFEIANT 465 ++ +K L + G+ + +T +A+++P +A+ I + Sbjct: 409 IRCTKGLSMHTFHGN----------------FFVRSTDLLSLANINPDAGFAVQLSIEES 452 Query: 466 AANSNPMMSAPGSADRPHLAYTQFITTYQHSSGTNRIRVTTVANQLLPFGTPA--IAASF 523 +++ L Q Y S G RIRV T+ LP + + A Sbjct: 453 LTDTS-------------LVCFQTALLYTSSKGERRIRVHTLC---LPVVSSLADVYAGV 496 Query: 524 DQEAAAVLMARIAVHKAETDDGADVIRWLDRTLIKLCQKYADYNKDDPQSFRLAP-NFSL 582 D +AA L+A +AV ++ + +D L ++ Y + S +AP + L Sbjct: 497 DVQAAICLLANMAVDRSVSSSLSDARDALVNAVVDSLSAYGSTVSNLQHSALMAPSSLKL 556 Query: 583 YPQFTY-YLRRSQFLSVFNNSPDETAFYRHIFTREDTTNSLIMIQPTLT 630 +P + L++ F + + D+ + + + + MI P L Sbjct: 557 FPLYVLALLKQKAFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLY 605 >2NUP-B nrPDB Length = 753 Score = 591 bits (1524), Expect = e-169, Method: Composition-based stats. Identities = 140/709 (19%), Positives = 264/709 (37%), Gaps = 119/709 (16%) Query: 2 DFET-NEDINGVRFTWNVFPSTRSDANSNVVPVGCLYTPLKEYDELNVAPYNPVVCSGPH 60 D + N + R T P T++ N +P+G L P K+ +L V + +V Sbjct: 35 DIQKLNCNPELFRCTLTSIPQTQALLNKAKLPLGLLLHPFKDLVQLPVVTSSTIV-RCRS 93 Query: 61 CKSILNPYCVIDPRNSSWSCPICNSRNHLPPQY------TNLSQENMPLELQSTTIEYIT 114 C++ +NP+ + W C +C N +P ++ + + E+Q+ TIE++ Sbjct: 94 CRTYINPFVSFLDQ-RRWKCNLCYRVNDVPEEFLYNPLTRVYGEPHRRPEVQNATIEFMA 152 Query: 115 NKPVTV----PPIFFFVVDLTS---ETENLDSLKESIITSLSLLPPNAL--IGLITYGNV 165 + PP++ FV D++ ET L+S+ +S++ +L LLP N IG IT+ + Sbjct: 153 PSEYMLRPPQPPVYLFVFDVSHNAVETGYLNSVCQSLLDNLDLLPGNTRTKIGFITFDST 212 Query: 166 VQLHDLSSETIDRCNVFRGDREYQLEALTEMLTGQKPTGPGGAASHLPNAMNKVTPFSLN 225 + + L + Q+ ++++ P Sbjct: 213 IHFYGLQESL----------SQPQMLIVSDIEDVFIPMP--------------------- 241 Query: 226 RFFLPLEQVEFKLNQLLENLSPDQWSVPAGHRPLRATGSALNIASLLLQGCYKNI---PA 282 E + LN+ E + ++P T SAL A LQ +K + Sbjct: 242 ------ENLLVNLNESKELVQDLLKTLPQMFTKTLETQSALGPA---LQAAFKLMSPTGG 292 Query: 283 RIILFASGPGTVAPGLIVNSELKDPLRSHHDIDSDHAQHYKKACKFYNQIAQRVAANGHT 342 R+ +F + T+ G + E + S DI H + FY ++A + Sbjct: 293 RMSVFQTQLPTLGVGALKPREEPNHRSSAKDI------HMTPSTDFYKKLALDCSGQQVA 346 Query: 343 VDIFAGCYDQIGMSEMKQLTDSTGGVLLLTDAFSTAIFKQSYLRLFAKDEEGYL--KMAF 400 VD+F ++ + ++ + G + ++ ++ K+ + YL K+ F Sbjct: 347 VDLFLLSGQYSDLASLGCISRYSAGSVYYYPSYHHQ-HNPVQVQKLQKELQRYLTRKIGF 405 Query: 401 NGNMAVKTSKDLKVQGLIGHASAVKKTDANNISESEIGIGATSTWKMASLSPYHSYAIFF 460 M ++ +K L + G+ + +T + +++P YA+ Sbjct: 406 EAVMRIRCTKGLSIHTFHGN----------------FFVRSTDLLSLPNVNPDAGYAV-- 447 Query: 461 EIANTAANSNPMMSAPGSADRPHLAYTQFITTYQHSSGTNRIRVTTVANQLLPFGTPA-- 518 MS S L Q Y S G RIRV T+ LP + Sbjct: 448 -----------QMSVEESLTDTQLVSFQSALLYTSSKGERRIRVHTLC---LPVVSTLND 493 Query: 519 IAASFDQEAAAVLMARIAVHKAETDDGADVIRWLDRTLIKLCQKYADYNKDDPQSFRLAP 578 + D +A + L+A +AV ++ T +D L +I Y + Q + P Sbjct: 494 VFLGADVQAISGLLANMAVDRSMTASLSDARDALVNAVIDSLSAYRSSVLSNQQPGLMVP 553 Query: 579 -NFSLYPQFTY-YLRRSQFLSVFNNSPDETAFYRHIFTREDTTNSLIMIQPTLT------ 630 + L+P F L++ F + N DE F + ++ P+L Sbjct: 554 FSLRLFPLFVLALLKQKSFQTGTNARLDERIFAMCQVKNQPLVYLMLTTHPSLYRVDNLS 613 Query: 631 ---SFSMEDD--PQPVLLDSI--SVKPNTILLLDTFFFILIYHGEQIAQ 672 + ++ D PQP +L + + L+D ++++ G+ Q Sbjct: 614 DEGALNISDRTIPQPPILQLSVEKLSRDGAFLMDAGSVLMLWVGKNCTQ 662 >3EH2-A nrPDB Length = 766 Score = 461 bits (1187), Expect = e-130, Method: Composition-based stats. Identities = 120/709 (16%), Positives = 234/709 (33%), Gaps = 115/709 (16%) Query: 4 ETNEDINGVRFTWNVFPSTRSDANSNVVPVGCLYTPLKEYDELNVAPY-------NPVVC 56 + N +R T P T A VP+ + PL +PY P+ C Sbjct: 38 QGNASPRYIRCTSYNIPCTSDMAKQAQVPLAAVIKPLARLPPEEASPYVVDHGESGPLRC 97 Query: 57 SGPHCKSILNPYCVIDPRNSSWSCPICNSRNHLPPQY--------TNLSQENMP-LELQS 107 + CK+ + P+ + C C+ N +PPQY + + P L L S Sbjct: 98 N--RCKAYMCPFMQFIEGGRRFQCCFCSCINDVPPQYFQHLDHTGKRVDAYDRPELSLGS 155 Query: 108 ----TTIEYITNKPVTVPPIFFFVVDLTSE---TENLDSLKESIITSLSLLPPNA----- 155 T++Y N PP F F++D++ T + L E + + L LP Sbjct: 156 YEFLATVDYCKNNKFPSPPAFIFMIDVSYNAIRTGLVRLLCEELKSLLDFLPREGGAEES 215 Query: 156 --LIGLITYGNVVQLHDLSSETIDRCNVFRGDREYQLEALTEMLTGQKPTGPGGAASHLP 213 +G +TY V+ +++ S + Q+ ++++ Sbjct: 216 AIRVGFVTYNKVLHFYNVKSSL----------AQPQMMVVSDVADM-------------- 251 Query: 214 NAMNKVTPFSLNRFFLPLEQVEFKLNQLLENLSPDQWSVPAGHRPLRATGSALNIASLLL 273 L+ F + + + + LL+ + P+ ++ + + +L Sbjct: 252 ------FVPLLDGFLVNVNESRAVITSLLDQI-PEMFADTRETETVFVPVIQAGMEALKA 304 Query: 274 QGCYKNIPARIILFASG-PGTVAPGLIVNSELKDPLRSHHDIDSDHAQH-YKKACKFYNQ 331 C ++ LF + P APG + N + I++D + ++ Y Sbjct: 305 AEC----AGKLFLFHTSLPIAEAPGKLKNRD------DRKLINTDKEKTLFQPQTGAYQT 354 Query: 332 IAQRVAANGHTVDIFAGCYDQIGMSEMKQLTDSTGGVLLLTDAFSTAIFKQSYLRLFAKD 391 +A+ A G VD+F + ++ + + TGG + +F ++ +L +D Sbjct: 355 LAKECVAQGCCVDLFLFPNQYVDVATLSVVPQLTGGSVYKYASFQVENDQERFLSDLRRD 414 Query: 392 EEGYLKMAFNGNMAVKTSKDLKVQGLIGHASAVKKTDANNISESEIGIGATSTWKMASLS 451 + + F+ M V+TS ++ G TD ++A L Sbjct: 415 VQKV--VGFDAVMRVRTSTGIRAVDFFGAFYMSNTTDV----------------ELAGLD 456 Query: 452 PYHSYAIFFEIANTAANSNPMMSAPGSADRPHLAYTQFITTYQHSSGTNRIRVTTVANQL 511 + + F+ + + A Q Y +G R+R+ +A Sbjct: 457 GDKTVTVEFKHDDRLNEESG-------------ALLQCALLYTSCAGQRRLRIHNLALNC 503 Query: 512 LPFGTPAIAASFDQEAAAVLMARIAVHKAETDDGADVIRWLDRTLIKLCQKYADYNKDDP 571 + + + MA+ A V L ++ Y Sbjct: 504 CTQLADL-YRNCETDTLINYMAKFAYRGVLNSPVKAVRDTLITQCAQILACYRKNCASPS 562 Query: 572 QSFRLA--PNFSLYPQFT-YYLRRSQFLSVFNNSPDETAFYRHIFTREDTTNSLIMIQPT 628 + +L L P + L+ + D+ A+ R + T D T + + P Sbjct: 563 SAGQLILPECMKLLPVYLNCVLKSDVLQPGAEVTTDDRAYVRQLVTSMDVTETNVFFYPR 622 Query: 629 LTSFSME-----DDPQPVLLDSISVKPNTILLLDTFFFILIYHGEQIAQ 672 L + +P V + I LL+ + ++ G + Q Sbjct: 623 LLPLTKSPVESTTEPPAVRASEERLSNGDIYLLENGLNLFLWVGASVQQ 671 >5KYW-B nrPDB Length = 770 Score = 459 bits (1181), Expect = e-129, Method: Composition-based stats. Identities = 119/662 (17%), Positives = 222/662 (33%), Gaps = 112/662 (16%) Query: 4 ETNEDINGVRFTWNVFPSTRSDANSNVVPVGCLYTPLKEYDE-------LNVAPYNPVVC 56 + N +R T FP T A +P+ + P +N PV C Sbjct: 42 QGNASPRFIRCTTYCFPCTSDMAKQAQIPLAAVIKPFATIPSNESPLYLVNHGESGPVRC 101 Query: 57 SGPHCKSILNPYCVIDPRNSSWSCPICNSRNHLPPQY--------TNLSQENMPLELQST 108 + CK+ + P+ + C CN N +PP Y L P EL Sbjct: 102 N--RCKAYMCPFMQFIEGGRRYQCGFCNCVNDVPPFYFQHLDHIGRRLDHYEKP-ELSLG 158 Query: 109 TIEYITN------KPVTVPPIFFFVVDLTSET---ENLDSLKESIITSLSLLPPNA---- 155 + EY+ PP F F++D++ + + E + T L +P Sbjct: 159 SYEYVATLDYCRKSKPPNPPAFIFMIDVSYSNIKNGLVKLICEELKTMLEKIPKEEQEET 218 Query: 156 ---LIGLITYGNVVQLHDLSSETIDRCNVFRGDREYQLEALTEMLTGQKPTGPGGAASHL 212 +G ITY V+ ++ S + Q+ +T+ Sbjct: 219 SAIRVGFITYNKVLHFFNVKSNL----------AQPQMMVVTD----------------- 251 Query: 213 PNAMNKVTPFSLNRFFLPLEQVEFKLNQLLENLSPDQWSVPAGHRPLRATGSALNIASLL 272 + +V L+ F + ++ + ++ LL+ + PD ++ + + A + +L Sbjct: 252 ---VGEVFVPLLDGFLVNYQESQSVIHNLLDQI-PDMFADSNENETVFAPVIQAGMEALK 307 Query: 273 LQGCYKNIPARIILFASG-PGTVAPGLIVNSELKDPLRSHHDIDSDHAQ-HYKKACKFYN 330 C P ++ +F S P APG + N + K +++D + ++ Y+ Sbjct: 308 AADC----PGKLFIFHSSLPTAEAPGKLKNRDDK------KLVNTDKEKILFQPQTNVYD 357 Query: 331 QIAQRVAANGHTVDIFAGCYDQIGMSEMKQLTDSTGGVLLLTDAFSTAIFKQSYLRLFAK 390 +A+ A+G +V +F + ++ + + TGG L + F + +Q +L Sbjct: 358 SLAKDCVAHGCSVTLFLFPSQYVDVASLGLVPQLTGGTLYKYNNFQMHLDRQQFLNDLRN 417 Query: 391 DEEGYLKMAFNGNMAVKTSKDLKVQGLIGHASAVKKTDANNISESEIGIGATSTWKMASL 450 D E K+ F+ M V+TS + G TD +MA++ Sbjct: 418 DIEK--KIGFDAIMRVRTSTGFRATDFFGGILMNNTTDV----------------EMAAI 459 Query: 451 SPYHSYAIFFEIANTAANSNPMMSAPGSADRPHLAYTQFITTYQHSSGTNRIRVTTVANQ 510 + + F+ + + + A Q Y SG R+R+ + Sbjct: 460 DCDKAVTVEFKHDDKLSEDSG-------------ALIQCAVLYTTISGQRRLRIHNLGLN 506 Query: 511 LLPFGTPAIAASFDQEAAAVLMARIAVHKAETDDGADVIRWLDRTLIKLCQKYAD--YNK 568 S + +A A+ A + L + Y + Sbjct: 507 CSSQLADL-YKSCETDALINFFAKSAFKAVLHQPLKVIREILVNQTAHMLACYRKNCASP 565 Query: 569 DDPQSFRLAPNFSLYPQFT-YYLRRSQFLSVFNNSPDETAFYRHIFTREDTTNSLIMIQP 627 L + + P + L+ LS S DE A+ R + +S + P Sbjct: 566 SAASQLILPDSMKVLPVYMNCLLKNCVLLSRPEISTDERAYQRQLVMTMGVADSQLFFYP 625 Query: 628 TL 629 L Sbjct: 626 QL 627 >1PD0-A nrPDB Length = 810 Score = 330 bits (845), Expect = 1e-90, Method: Composition-based stats. Identities = 114/655 (17%), Positives = 213/655 (32%), Gaps = 99/655 (15%) Query: 5 TNEDINGVRFTWNVFPSTRSDANSNVVPVGCLYTPLKE-YDELNVAPYNP--VVCSGPHC 61 +N + +R T N P S + +P G + P + YD+++ P N ++ C Sbjct: 59 SNASPDYIRSTLNAVPKNSSLLKKSKLPFGLVIRPYQHLYDDIDPPPLNEDGLIVRCRRC 118 Query: 62 KSILNPYCVIDPRNSSWSCPICNSRNHLPPQYTNLSQENMPL------ELQSTTIEYITN 115 +S +NP+ + W C C N +P Q + S N P E++ +EY+ Sbjct: 119 RSYMNPFVTFIEQGRRWRCNFCRLANDVPMQ-MDQSDPNDPKSRYDRNEIKCAVMEYMAP 177 Query: 116 KPVTV----PPIFFFVVDLTSETENLDSLKESIIT---SLSLLPPN---ALIGLITYGNV 165 K T+ P + F++D++ + L +I T +L +P + I ++ N Sbjct: 178 KEYTLRQPPPATYCFLIDVSQSSIKSGLLATTINTLLQNLDSIPNHDERTRISILCVDNA 237 Query: 166 VQLHDLSSETIDRCNVFRGDREYQLEALTEMLTGQKPTGPGGAASHLPNAMNKVTPFSLN 225 + + +D N + + + ++ P N Sbjct: 238 IHYFKIP---LDSENNEESADQINMMDIADLEEPFLPRP--------------------N 274 Query: 226 RFFLPLEQVEFKLNQLLENLSPDQWSVPAGHRPLRATGSALNIASLLLQGCYKNIPARII 285 + L+ + LL + P + T AL A + +II Sbjct: 275 SMVVSLKACRQNIETLLTKI-------PQIFQSNLITNFALGPALKSAYHLIGGVGGKII 327 Query: 286 LFASGPGTVAPGLIVNSELKDPLRSHHDIDSDHAQHYKKACKFYNQIAQRVAANGHTVDI 345 + + + G + + + + AQ FY + TVD+ Sbjct: 328 VVSGTLPNLGIGKLQRRNESGVVNT----SKETAQLLSCQDSFYKNFTIDCSKVQITVDL 383 Query: 346 FAGCYDQIGMSEMKQLTDSTGGVLLLTDAFSTAIFKQSYLRLFAKDEEGYLKMAF--NGN 403 F D + ++ + L+ T G FS + + F+ + ++ M F Sbjct: 384 FLASEDYMDVASLSNLSRFTAGQTHFYPGFSGK--NPNDIVKFSTEFAKHISMDFCMETV 441 Query: 404 MAVKTSKDLKVQGLIGHASAVKKTDANNISESEIGIGATSTWKMASLSPYHSYAIFFEIA 463 M + S L++ GH ++ +++ SY + Sbjct: 442 MRARGSTGLRMSRFYGH----------------FFNRSSDLCAFSTMPRDQSYLFEVNVD 485 Query: 464 NTAANSNPMMSAPGSADRPHLAYTQFITTYQHSSGTNRIRVTTVANQLLPFGTPA--IAA 521 + Y Q ++ RIR+ T+A +P + A Sbjct: 486 ESIM--------------ADYCYVQVAVLLSLNNSQRRIRIITLA---MPTTESLAEVYA 528 Query: 522 SFDQEAAAVLMARIAVHKAETDDGADVIRWLDRTLIKLCQKYAD----YNKDDPQSFRLA 577 S DQ A A AV KA D +++++ + Y N RL Sbjct: 529 SADQLAIASFYNSKAVEKALNSSLDDARVLINKSVQDILATYKKEIVVSNTAGGAPLRLC 588 Query: 578 PNFSLYPQFTYYL-RRSQFLSVFNNSPDETAFYRHIFTREDTTNSLIMIQPTLTS 631 N ++P + L + F S S D A + + I P + S Sbjct: 589 ANLRMFPLLMHSLTKHMAFRSGIVPS-DHRASALNNLESLPLKYLIKNIYPDVYS 642 >1M2V-B nrPDB Length = 926 Score = 324 bits (829), Expect = 1e-88, Method: Composition-based stats. Identities = 114/655 (17%), Positives = 213/655 (32%), Gaps = 99/655 (15%) Query: 5 TNEDINGVRFTWNVFPSTRSDANSNVVPVGCLYTPLKE-YDELNVAPYNP--VVCSGPHC 61 +N + +R T N P S + +P G + P + YD+++ P N ++ C Sbjct: 175 SNASPDYIRSTLNAVPKNSSLLKKSKLPFGLVIRPYQHLYDDIDPPPLNEDGLIVRCRRC 234 Query: 62 KSILNPYCVIDPRNSSWSCPICNSRNHLPPQYTNLSQENMPL------ELQSTTIEYITN 115 +S +NP+ + W C C N +P Q + S N P E++ +EY+ Sbjct: 235 RSYMNPFVTFIEQGRRWRCNFCRLANDVPMQ-MDQSDPNDPKSRYDRNEIKCAVMEYMAP 293 Query: 116 KPVTV----PPIFFFVVDLTSETENLDSLKESIIT---SLSLLPPN---ALIGLITYGNV 165 K T+ P + F++D++ + L +I T +L +P + I ++ N Sbjct: 294 KEYTLRQPPPATYCFLIDVSQSSIKSGLLATTINTLLQNLDSIPNHDERTRISILCVDNA 353 Query: 166 VQLHDLSSETIDRCNVFRGDREYQLEALTEMLTGQKPTGPGGAASHLPNAMNKVTPFSLN 225 + + +D N + + + ++ P N Sbjct: 354 IHYFKIP---LDSENNEESADQINMMDIADLEEPFLPRP--------------------N 390 Query: 226 RFFLPLEQVEFKLNQLLENLSPDQWSVPAGHRPLRATGSALNIASLLLQGCYKNIPARII 285 + L+ + LL + P + T AL A + +II Sbjct: 391 SMVVSLKACRQNIETLLTKI-------PQIFQSNLITNFALGPALKSAYHLIGGVGGKII 443 Query: 286 LFASGPGTVAPGLIVNSELKDPLRSHHDIDSDHAQHYKKACKFYNQIAQRVAANGHTVDI 345 + + + G + + + + AQ FY + TVD+ Sbjct: 444 VVSGTLPNLGIGKLQRRNESGVVNT----SKETAQLLSCQDSFYKNFTIDCSKVQITVDL 499 Query: 346 FAGCYDQIGMSEMKQLTDSTGGVLLLTDAFSTAIFKQSYLRLFAKDEEGYLKMAF--NGN 403 F D + ++ + L+ T G FS + + F+ + ++ M F Sbjct: 500 FLASEDYMDVASLSNLSRFTAGQTHFYPGFSGK--NPNDIVKFSTEFAKHISMDFCMETV 557 Query: 404 MAVKTSKDLKVQGLIGHASAVKKTDANNISESEIGIGATSTWKMASLSPYHSYAIFFEIA 463 M + S L++ GH ++ +++ SY + Sbjct: 558 MRARGSTGLRMSRFYGH----------------FFNRSSDLCAFSTMPRDQSYLFEVNVD 601 Query: 464 NTAANSNPMMSAPGSADRPHLAYTQFITTYQHSSGTNRIRVTTVANQLLPFGTPA--IAA 521 + Y Q ++ RIR+ T+A +P + A Sbjct: 602 ESIM--------------ADYCYVQVAVLLSLNNSQRRIRIITLA---MPTTESLAEVYA 644 Query: 522 SFDQEAAAVLMARIAVHKAETDDGADVIRWLDRTLIKLCQKYAD----YNKDDPQSFRLA 577 S DQ A A AV KA D +++++ + Y N RL Sbjct: 645 SADQLAIASFYNSKAVEKALNSSLDDARVLINKSVQDILATYKKEIVVSNTAGGAPLRLC 704 Query: 578 PNFSLYPQFTYYL-RRSQFLSVFNNSPDETAFYRHIFTREDTTNSLIMIQPTLTS 631 N ++P + L + F S S D A + + I P + S Sbjct: 705 ANLRMFPLLMHSLTKHMAFRSGIVPS-DHRASALNNLESLPLKYLIKNIYPDVYS 758 >3CZE-A nrPDB Length = 644 Score = 30.2 bits (66), Expect = 3.5, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 18/37 (48%) Query: 663 LIYHGEQIAQWRKAGYQDDPQYADFKALLEEPKLEAA 699 LIY G+++A GY+DDP L P ++ Sbjct: 489 LIYMGDELAMVNDPGYRDDPHRQHEGRWLHRPAMDWQ 525 >1SKZ-A nrPDB Length = 119 Score = 29.8 bits (65), Expect = 4.2, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 13/31 (41%), Gaps = 4/31 (12%) Query: 56 CSGPHCKSILNPYCVIDPRNSSWSCPICNSR 86 CSG C+ P+ + S + C C R Sbjct: 28 CSGVRCRVH-CPHGF---QRSRYGCEFCKCR 54 >3L5K-A nrPDB Length = 250 Score = 29.0 bits (63), Expect = 7.0, Method: Composition-based stats. Identities = 23/86 (26%), Positives = 35/86 (40%), Gaps = 16/86 (18%) Query: 628 TLTSFSMEDDPQPV---LLDSISVKPNTILLLDTFFFILIYHGEQIAQWRKAGYQDDPQY 684 L SM PQPV + D + +T L F + ++ W Sbjct: 17 NLYFQSMAAPPQPVTHLIFDMDGLLLDTERLYSVVFQEICNRYDKKYSW----------- 65 Query: 685 ADFKALLEEPK-LEAAELLVDRFPLP 709 D K+L+ K LEAA++++D LP Sbjct: 66 -DVKSLVMGKKALEAAQIIIDVLQLP 90 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.121 0.309 Lambda K H 0.267 0.0366 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,476,086 Number of Sequences: 36641 Number of extensions: 969285 Number of successful extensions: 2440 Number of sequences better than 10.0: 11 Number of HSP's better than 10.0 without gapping: 14 Number of HSP's successfully gapped in prelim test: 8 Number of HSP's that attempted gapping in prelim test: 2337 Number of HSP's gapped (non-prelim): 31 length of query: 768 length of database: 10,336,785 effective HSP length: 105 effective length of query: 663 effective length of database: 6,489,480 effective search space: 4302525240 effective search space used: 4302525240 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 63 (29.0 bits)