BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P15202 (515 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1A4E-A nrPDB 1028 0.0 2XQ1-A nrPDB 588 e-168 5GKN-A nrPDB 468 e-132 1QQW-A nrPDB 462 e-130 3HB6-A nrPDB 404 e-113 2IQF-A nrPDB 396 e-110 4E37-A nrPDB 393 e-109 1SI8-A nrPDB 392 e-109 2ISA-A nrPDB 391 e-109 4B7G-A nrPDB 370 e-103 4QOP-A nrPDB 369 e-102 1GWF-A nrPDB 366 e-101 2J2M-A nrPDB 327 7e-90 4CAB-A nrPDB 323 1e-88 3TTT-A nrPDB 318 5e-87 1M7S-A nrPDB 295 2e-80 1SY7-A nrPDB 289 2e-78 4BIM-A nrPDB 281 4e-76 4B7A-A nrPDB 280 1e-75 2IUF-A nrPDB 277 7e-75 1YE9-A nrPDB 181 8e-46 1YE9-E nrPDB 137 8e-33 3E4Y-A nrPDB 60 3e-09 6DFZ-A nrPDB 35 0.085 3P56-A nrPDB 32 0.58 2HW6-A nrPDB 30 1.9 1F1U-A nrPDB 30 2.0 2GJP-A nrPDB 29 4.1 4UXR-C nrPDB 29 4.8 6GN6-A nrPDB 28 8.9 >1A4E-A nrPDB Length = 488 Score = 1028 bits (2658), Expect = 0.0, Method: Compositional matrix adjust. Identities = 488/488 (100%), Positives = 488/488 (100%) Query: 15 DVREDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGS 74 DVREDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGS Sbjct: 1 DVREDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGS 60 Query: 75 GAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTE 134 GAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTE Sbjct: 61 GAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTE 120 Query: 135 EGNLDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVM 194 EGNLDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVM Sbjct: 121 EGNLDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVM 180 Query: 195 ILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSN 254 ILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSN Sbjct: 181 ILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSN 240 Query: 255 PDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIV 314 PDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIV Sbjct: 241 PDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIV 300 Query: 315 LNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNC 374 LNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNC Sbjct: 301 LNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNC 360 Query: 375 PYASKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGPAIPYHW 434 PYASKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGPAIPYHW Sbjct: 361 PYASKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGPAIPYHW 420 Query: 435 ATSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFARVDKGLS 494 ATSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFARVDKGLS Sbjct: 421 ATSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFARVDKGLS 480 Query: 495 EAIKKVAE 502 EAIKKVAE Sbjct: 481 EAIKKVAE 488 >2XQ1-A nrPDB Length = 509 Score = 588 bits (1517), Expect = e-168, Method: Compositional matrix adjust. Identities = 291/508 (57%), Positives = 361/508 (71%), Gaps = 19/508 (3%) Query: 21 VVTNSTGNPINEPFVTQRIGEH----------GPLLLQDYNLIDSLAHFNRENIPQRNPH 70 V T S G P+++PF TQRI GPLLLQD+ LID+L+HF+RE IP+R H Sbjct: 8 VFTTSQGCPVSDPFTTQRIPLDSTGYKYAPPIGPLLLQDFKLIDTLSHFDRERIPERVVH 67 Query: 71 AHGSGAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATK 130 A G+GA+G FEVTDDITD+C + +GK+T+ TRFSTVGG+KGSADT RDPRGFATK Sbjct: 68 AKGAGAYGVFEVTDDITDVCSAKFLDTVGKKTRIFTRFSTVGGEKGSADTARDPRGFATK 127 Query: 131 FYTEEGNLDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAI 190 FYTE+GNLD VYNNTP+FFIRDP KFPHFIHTQKRNP TNL+D +MFWD+LT N ++ Sbjct: 128 FYTEDGNLDLVYNNTPIFFIRDPIKFPHFIHTQKRNPATNLKDPNMFWDYLTA--NDESL 185 Query: 191 HQVMILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKI 250 HQVM LFS+RGTPA+YR+M+GYSGHTYKW N G+W YVQVH +QG+ NL EEA ++ Sbjct: 186 HQVMYLFSNRGTPASYRTMNGYSGHTYKWYNSKGEWVYVQVHFIANQGVHNLLDEEAGRL 245 Query: 251 AGSNPDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRV 310 AG +PD+ +DL+EAI+ G+YPSW YIQTMT +KKLPFSVFDLTKVWP FPLR Sbjct: 246 AGEDPDHSTRDLWEAIEKGDYPSWECYIQTMTLEQSKKLPFSVFDLTKVWPHKDFPLRHF 305 Query: 311 GKIVLNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQI 370 G+ LNENP N++A+ EQ AF+PS TVP E S DPVLQ+RLFSY D HR+RLGPN+HQI Sbjct: 306 GRFTLNENPKNYYAETEQIAFSPSHTVPGMEPSNDPVLQSRLFSYPDTHRHRLGPNYHQI 365 Query: 371 PVNCPYASKFFNPAIRDGPMNVNGNFGSEPTYL-ANDKSYTY-IQQDRPIQQHQEVWNGP 428 PVNCP S FNP RDGPM V+GN G P Y A + Y + + E + G Sbjct: 366 PVNCPLKSGSFNPINRDGPMCVDGNLGGTPNYANAYNCPIQYAVSPKASGNKPDEKYTGE 425 Query: 429 AIPYHWATSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFAR 488 +PYHW + D D+ Q + ++VLG+ PG+Q++L N+ HV A IQ RVY+ F++ Sbjct: 426 VVPYHWEHT--DYDYFQPKMFWKVLGRTPGEQESLVKNVANHVSAADEFIQDRVYEYFSK 483 Query: 489 VDKGLSEAI-KKVAEAKHASELSSNSKF 515 + + + I KKV E K + SS SK Sbjct: 484 AEPIIGDLIRKKVQELKRKA--SSPSKI 509 >5GKN-A nrPDB Length = 527 Score = 468 bits (1205), Expect = e-132, Method: Compositional matrix adjust. Identities = 250/510 (49%), Positives = 322/510 (63%), Gaps = 27/510 (5%) Query: 21 VVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAFGYF 80 V+T GNP+ + + +G GPLL+QD D +AHF+RE IP+R HA G+GAFGYF Sbjct: 26 VLTTGGGNPVGDKLNSLTVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYF 85 Query: 81 EVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNLDW 140 EVT DIT + +F IGKRT RFSTV G+ GSADTVRDPRGFA KFYTE+GN D Sbjct: 86 EVTHDITRYSKAKVFEHIGKRTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDL 145 Query: 141 VYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTT-PENQVAIHQVMILFSD 199 V NNTP+FFIRD FP FIH+QKRNPQT+L+D DM WDF + PE ++HQV LFSD Sbjct: 146 VGNNTPIFFIRDALLFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPE---SLHQVSFLFSD 202 Query: 200 RGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDYCQ 259 RG P +R M+GY HT+K N NG+ Y + H KTDQGIKNL++E+A ++A +PDY Sbjct: 203 RGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLAHEDPDYGL 262 Query: 260 QDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNENP 319 +DLF AI GNYPSWT+YIQ MT +A+ PF+ FDLTKVWP G +PL VGK+VLN NP Sbjct: 263 RDLFNAIATGNYPSWTLYIQVMTFSEAEIFPFNPFDLTKVWPHGDYPLIPVGKLVLNRNP 322 Query: 320 LNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNCPYASK 379 +N+FA+VEQ AF PS P E S D +LQ RLF+Y D HR+RLGPN+ QIPVNCPY ++ Sbjct: 323 VNYFAEVEQLAFDPSNMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVNCPYRAR 382 Query: 380 FFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGPAIPYHWATSPG 439 N RDGPM + N G P Y N S++ + +H+ ++G + S Sbjct: 383 VAN-YQRDGPMCMMDNQGGAPNYYPN--SFSAPEHQPSALEHRTHFSGDVQRF---NSAN 436 Query: 440 DVDFVQARNLY-RVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFARVDKGLSEAIK 498 D + Q R Y +VL ++ Q+K L NI H++ A IQ++ F+ V I+ Sbjct: 437 DDNVTQVRTFYLKVLNEE--QRKRLCENIAGHLKDAQLFIQKKAVKNFSDVHPEYGSRIQ 494 Query: 499 KVAE--------------AKHASELSSNSK 514 + + +H S LS+ K Sbjct: 495 ALLDKYNEEKPKNAVHTYVQHGSHLSAREK 524 >1QQW-A nrPDB Length = 527 Score = 462 bits (1188), Expect = e-130, Method: Compositional matrix adjust. Identities = 244/490 (49%), Positives = 312/490 (63%), Gaps = 13/490 (2%) Query: 21 VVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAFGYF 80 V+T GNP+ + +G GPLL+QD D +AHF+RE IP+R HA G+GAFGYF Sbjct: 26 VLTTGAGNPVGDKLNVITVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYF 85 Query: 81 EVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNLDW 140 EVT DIT + +F IGK+T RFSTV G+ GSADTVRDPRGFA KFYTE+GN D Sbjct: 86 EVTHDITKYSKAKVFEHIGKKTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDL 145 Query: 141 VYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTT-PENQVAIHQVMILFSD 199 V NNTP+FFIRDP FP FIH+QKRNPQT+L+D DM WDF + PE ++HQV LFSD Sbjct: 146 VGNNTPIFFIRDPILFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPE---SLHQVSFLFSD 202 Query: 200 RGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDYCQ 259 RG P +R M+GY HT+K N NG+ Y + H KTDQGIKNL++E+A +++ +PDY Sbjct: 203 RGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLSQEDPDYGI 262 Query: 260 QDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNENP 319 +DLF AI G YPSWT YIQ MT A+ PF+ FDLTKVWP +PL VGK+VLN NP Sbjct: 263 RDLFNAIATGKYPSWTFYIQVMTFNQAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNRNP 322 Query: 320 LNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNCPYASK 379 +N+FA+VEQ AF PS P EAS D +LQ RLF+Y D HR+RLGPN+ IPVNCPY ++ Sbjct: 323 VNYFAEVEQIAFDPSNMPPGIEASPDKMLQGRLFAYPDTHRHRLGPNYLHIPVNCPYRAR 382 Query: 380 FFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGPAIPYHWATSPG 439 N RDGPM + N G P Y N S+ +Q +H ++G ++ A Sbjct: 383 VAN-YQRDGPMCMQDNQGGAPNYYPN--SFGAPEQQPSALEHSIQYSGEVRRFNTAN--- 436 Query: 440 DVDFVQARNLY-RVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFARVDKGLSEAIK 498 D + Q R Y VL ++ Q+K L NI H++ A IQ++ F V I+ Sbjct: 437 DDNVTQVRAFYVNVLNEE--QRKRLCENIAGHLKDAQIFIQKKAVKNFTEVHPDYGSHIQ 494 Query: 499 KVAEAKHASE 508 + + +A + Sbjct: 495 ALLDKYNAEK 504 >3HB6-A nrPDB Length = 484 Score = 404 bits (1037), Expect = e-113, Method: Compositional matrix adjust. Identities = 224/494 (45%), Positives = 298/494 (60%), Gaps = 17/494 (3%) Query: 18 EDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAF 77 E + +T + G P+ + G GP+LLQD ++ LAHF+RE IP+R A GSGAF Sbjct: 2 EKKKLTTAAGAPVVDNNNVITAGPRGPMLLQDVWFLEKLAHFDREVIPERRMFAKGSGAF 61 Query: 78 GYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGN 137 G F VT DIT + +FS++GK+T+ RFSTV G++G+AD RD RGFA KFYTEEGN Sbjct: 62 GTFTVTHDITKYTRAKIFSEVGKKTEMFARFSTVAGERGAADAERDIRGFALKFYTEEGN 121 Query: 138 LDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLT-TPENQVAIHQVMIL 196 D V NNTPVF++RDP KFP H KR+P+TN+R+ WDF + PE ++HQ+ I Sbjct: 122 WDMVGNNTPVFYLRDPLKFPDLNHIVKRDPRTNMRNMAYKWDFFSHLPE---SLHQLTID 178 Query: 197 FSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPD 256 SDRG P +YR +HG+ HTY + NK+ + +V+ H + QGIKNL +EA + G + + Sbjct: 179 MSDRGLPLSYRFVHGFGSHTYSFINKDNERFWVKFHFRCQQGIKNLMDDEAEALVGKDRE 238 Query: 257 YCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLN 316 Q+DLFEAI+ G+YP W + IQ M E++A +P++ FDLTKVWP +PL VG LN Sbjct: 239 SSQRDLFEAIERGDYPRWKLQIQIMPEKEASTVPYNPFDLTKVWPHADYPLMDVGYFELN 298 Query: 317 ENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNCPY 376 NP N+F+ VEQAAF+P+ VP S D +LQ RLFSY DAHRYRLG N HQIPVN P Sbjct: 299 RNPDNYFSDVEQAAFSPANIVPGISFSPDKMLQGRLFSYGDAHRYRLGVNHHQIPVNAPK 358 Query: 377 ASKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGPAIPYHWAT 436 F+ RDG M V+GN G+ TY N S Q+ ++ G A HW Sbjct: 359 CP--FHNYHRDGAMRVDGNSGNGITYEPN--SGGVFQEQPDFKEPPLSIEGAAD--HWNH 412 Query: 437 SPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFARV----DKG 492 + F Q R LY +L + + + I + A + QQR D+F +V G Sbjct: 413 REDEDYFSQPRALYELLSDD--EHQRMFARIAGELSQASKETQQRQIDLFTKVHPEYGAG 470 Query: 493 LSEAIKKVAEAKHA 506 + +AI KV E K A Sbjct: 471 VEKAI-KVLEGKDA 483 >2IQF-A nrPDB Length = 505 Score = 396 bits (1018), Expect = e-110, Method: Compositional matrix adjust. Identities = 228/501 (45%), Positives = 299/501 (59%), Gaps = 32/501 (6%) Query: 16 VREDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSG 75 V +D T + G P+ + G GP+LLQ ++ LA F+RE IP+R HA GSG Sbjct: 2 VNKDVKQTTAFGAPVWDDNNVITAGPRGPVLLQSTWFLEKLAAFDRERIPERVVHAKGSG 61 Query: 76 AFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEE 135 A+G F VT DIT + +FSK+GK+T+C RFSTV G++GSAD VRDPRGFA K+YTEE Sbjct: 62 AYGTFTVTKDITKYTKAKIFSKVGKKTECFFRFSTVAGERGSADAVRDPRGFAMKYYTEE 121 Query: 136 GNLDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLT-TPENQVAIHQVM 194 GN D V NNTPVFFIRD KFP FIHTQKR+PQTNL + DM WDF + PE +++QV Sbjct: 122 GNWDLVGNNTPVFFIRDAIKFPDFIHTQKRDPQTNLPNHDMVWDFWSNVPE---SLYQVT 178 Query: 195 ILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSN 254 + SDRG P ++R M G+ HT+ N G+ +V+ H T QG+K+LT EEA +I + Sbjct: 179 WVMSDRGIPKSFRHMDGFGSHTFSLINAKGERFWVKFHFHTMQGVKHLTNEEAAEIRKHD 238 Query: 255 PDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIV 314 PD Q+DLF+AI G+YP W + IQ M E DAKK F FD+TK+W +PL VG + Sbjct: 239 PDSNQRDLFDAIARGDYPKWKLSIQVMPEEDAKKYRFHPFDVTKIWYTQDYPLMEVGIVE 298 Query: 315 LNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNC 374 LN+NP N+FA+VEQAAF P+ VP S D +LQ RLFSY D HRYRLG N+ QIPVN Sbjct: 299 LNKNPENYFAEVEQAAFTPANVVPGIGYSPDRMLQGRLFSYGDTHRYRLGVNYPQIPVNK 358 Query: 375 PYASKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRP----------IQQHQEV 424 P F+ + RDG M NG +GS Y + S ++D+ I++ EV Sbjct: 359 PRCP--FHSSSRDGYMQ-NGYYGSLQNYTPS--SLPGYKEDKSARDPKFNLAHIEKEFEV 413 Query: 425 WNGPAIPYHWATSPGDVD-FVQARNLYRVLGKQPGQQKNLAYN-IGIHVEGAC-PQIQQR 481 WN W D D + Q + YR L P +K ++ IG + +I + Sbjct: 414 WN-------WDYRADDSDYYTQPGDYYRSL---PADEKERLHDTIGESLAHVTHKEIVDK 463 Query: 482 VYDMFARVDKGLSEAIKKVAE 502 + F + D +E +KK E Sbjct: 464 QLEHFKKADPKYAEGVKKALE 484 >4E37-A nrPDB Length = 484 Score = 393 bits (1009), Expect = e-109, Method: Compositional matrix adjust. Identities = 218/497 (43%), Positives = 299/497 (60%), Gaps = 23/497 (4%) Query: 18 EDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAF 77 E +T + G P+ + Q G GP+LLQD ++ LAHF+RE IP+R HA GS A+ Sbjct: 1 EKTRLTTAAGAPVVDNQNVQTAGPRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSAAY 60 Query: 78 GYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGN 137 G F VT DIT + +FS++GK+T RFSTV G++G+AD RD RGF+ +FYTE+GN Sbjct: 61 GTFTVTHDITPYTRAKIFSQVGKKTDMFLRFSTVAGERGAADAERDIRGFSMRFYTEQGN 120 Query: 138 LDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLT-TPENQVAIHQVMIL 196 D V NNTPVF++RDP KFP H KR+P+TNLR+A WDF + PE ++HQ+ I Sbjct: 121 WDLVGNNTPVFYLRDPLKFPDLNHVVKRDPRTNLRNATFKWDFFSHLPE---SLHQLTID 177 Query: 197 FSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPD 256 FSDRG P +YR +HG+ HT+ + N N + +V+ H KT QGI+NLT EA ++ + + Sbjct: 178 FSDRGLPKSYRHIHGFGSHTFSFINANNERFWVKFHFKTQQGIENLTNAEAAEVIAQDRE 237 Query: 257 YCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLN 316 Q+DL+E+I+ G++P W +Y+Q M E++A ++ FDLTKVWP G +PL VG LN Sbjct: 238 SSQRDLYESIEKGDFPRWKMYVQIMPEKEAATYRYNPFDLTKVWPHGDYPLIEVGFFELN 297 Query: 317 ENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVN--- 373 NP N+FA+VEQAAF P+ VP S D +LQ RLFSY DAHRYRLG N HQIPVN Sbjct: 298 RNPDNYFAEVEQAAFTPANVVPGIGFSPDKMLQGRLFSYGDAHRYRLGVNHHQIPVNAAR 357 Query: 374 CPYASKFFNPAIRDGPMNVNGNFGSEP-TYLANDKSYTYIQQDRPIQQHQEVWNGPAIPY 432 CP+ RDG M V+GN + TY N S+ Q+ + G A Sbjct: 358 CPHQVYH-----RDGGMRVDGNNAHQRVTYEPN--SFNQWQEQPDFSEPPLSLEGAAD-- 408 Query: 433 HWATSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFARVD-- 490 HW D + Q L+ + + Q++ L NI + QIQ+R +F +VD Sbjct: 409 HWNHRVDDDYYSQPAALFHLFTDE--QKQRLFANIAEDIRDVPEQIQRRQIGLFLKVDPA 466 Query: 491 --KGLSEAIKKVAEAKH 505 KG+++A+ +A H Sbjct: 467 YGKGVADALGLKLDAAH 483 >1SI8-A nrPDB Length = 484 Score = 392 bits (1007), Expect = e-109, Method: Compositional matrix adjust. Identities = 217/487 (44%), Positives = 300/487 (61%), Gaps = 21/487 (4%) Query: 22 VTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAFGYFE 81 +T S G+P+ + + GE GP+L+QD +L++ LAHFNRE +P+R HA G+GA G F+ Sbjct: 6 LTTSQGSPVGDNQNSLTAGEFGPVLIQDVHLLEKLAHFNRERVPERVVHAKGAGAHGIFK 65 Query: 82 VTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNLDWV 141 V+ + + S++GK T RFSTV G+ GS+DT+RDPRGFA KFYT+EGN D V Sbjct: 66 VSQSMAQYTKADFLSEVGKETPLFARFSTVAGELGSSDTLRDPRGFALKFYTDEGNYDLV 125 Query: 142 YNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLT-TPENQVAIHQVMILFSDR 200 NNTP+FFIRD KFP FIH+QKRNP+T+L+ + WDF + +PE ++HQV IL SDR Sbjct: 126 GNNTPIFFIRDAIKFPDFIHSQKRNPRTHLKSPEAVWDFWSHSPE---SLHQVTILMSDR 182 Query: 201 GTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDYCQQ 260 G P ++R MHG+ HT+KW N G+ +V+ H KT+QGIKNL + A +IAG NPD+ + Sbjct: 183 GIPLSFRHMHGFGSHTFKWVNAAGEVFFVKYHFKTNQGIKNLESQLAEEIAGKNPDFHIE 242 Query: 261 DLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNENPL 320 DL AI+N +PSWT+ +Q + DA + ++FD+TK Q ++PL VG + LN NP Sbjct: 243 DLHNAIENQEFPSWTLSVQIIPYADALTMKETLFDVTKTVSQKEYPLIEVGTMTLNRNPE 302 Query: 321 NFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNCPYASKF 380 N+FA+VEQ F+P VP EAS D +LQ RLF+Y DAHR+R+G N HQ+P+N A Sbjct: 303 NYFAEVEQVTFSPGNFVPGIEASPDKLLQGRLFAYGDAHRHRVGANSHQLPINQAKAP-- 360 Query: 381 FNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEV-WNGPAIPYHWATSPG 439 N +DG M N N SE Y N SYT ++ P + G Y + Sbjct: 361 VNNYQKDGNMRFN-NGNSEINYEPN--SYTETPKEDPTAKISSFEVEGNVGNYSYNQD-- 415 Query: 440 DVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQ-IQQRVYDMFARVD----KGLS 494 F QA LY +L + +++NL NI + Q I R D+F RV+ ++ Sbjct: 416 --HFTQANALYNLLPSE--EKENLINNIAASLGQVKNQEIIARQIDLFTRVNPEYGARVA 471 Query: 495 EAIKKVA 501 +AIK+ A Sbjct: 472 QAIKQQA 478 >2ISA-A nrPDB Length = 483 Score = 391 bits (1005), Expect = e-109, Method: Compositional matrix adjust. Identities = 214/482 (44%), Positives = 286/482 (59%), Gaps = 12/482 (2%) Query: 20 RVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAFGY 79 + +T + G P+ Q G+ GP LLQD ++ LAHF+RE IP+R HA GSGA+G Sbjct: 3 KKLTTAAGCPVAHNQNVQTAGKRGPQLLQDVWFLEKLAHFDREVIPERRMHAKGSGAYGT 62 Query: 80 FEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNLD 139 F VT DIT + +FS IGK+T RFSTV G++G+AD RD RGF+ KFYTEEGN D Sbjct: 63 FTVTHDITKYTKAKIFSDIGKKTDMFARFSTVAGERGAADAERDIRGFSLKFYTEEGNWD 122 Query: 140 WVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTT-PENQVAIHQVMILFS 198 NNTPVFF+RDP KFP H KR+P+TN+R A WDF T+ PE A+HQV I+ S Sbjct: 123 LAGNNTPVFFLRDPLKFPDLNHAVKRDPRTNMRSAKNNWDFWTSLPE---ALHQVTIVMS 179 Query: 199 DRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDYC 258 DRG PA YR MHG+ HT+ + N + + ++V+ H + QGIKNL+ EA ++ G++ + Sbjct: 180 DRGIPATYRHMHGFGSHTFSFINSDNERYWVKFHFVSQQGIKNLSDAEAGELVGNDRESH 239 Query: 259 QQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNEN 318 Q+DL ++I N ++P WT+ +Q M E DA +P++ FDLTKVWP +PL VG+ LN N Sbjct: 240 QRDLLDSIDNQDFPKWTLKVQIMPEADAATVPYNPFDLTKVWPHKDYPLIEVGEFELNRN 299 Query: 319 PLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNCPYAS 378 P N+FA+VEQAAF P+ VP S D +LQ RLF+Y DA RYRLG N IPVN P Sbjct: 300 PQNYFAEVEQAAFNPANVVPGISFSPDKMLQGRLFAYGDAQRYRLGVNHQHIPVNAPRCP 359 Query: 379 KFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGPAIPYHWATSP 438 + RDG M V+GNFGS Y ND+ Q D + N HW Sbjct: 360 --VHSYHRDGAMRVDGNFGSTLGYEPNDQGQWAEQPDFS----EPPLNLDGAAAHWDHRE 413 Query: 439 GDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFARVDKGLSEAIK 498 + F Q +L+ ++ + +Q L N ++ G +IQ R + D E I Sbjct: 414 DEDYFSQPGDLFGLMTAE--KQAILFDNTARNLNGVPKEIQLRHVTHCYKADPAYGEGIG 471 Query: 499 KV 500 K+ Sbjct: 472 KL 473 >4B7G-A nrPDB Length = 515 Score = 370 bits (950), Expect = e-103, Method: Compositional matrix adjust. Identities = 212/501 (42%), Positives = 283/501 (56%), Gaps = 23/501 (4%) Query: 22 VTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAFGYFE 81 T G P+ ++ G GP +L D +LI+ LAHFNREN+P+R PHA G GAFG Sbjct: 22 TTRHNGAPVPSENISATAGPQGPNVLNDIHLIEKLAHFNRENVPERIPHAKGHGAFGELH 81 Query: 82 VTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNLDWV 141 +T+D+++ + +F + GK T RFSTV G++GS DT RD GFA +FYTEEGN D V Sbjct: 82 ITEDVSEYTKADLF-QPGKVTPLAVRFSTVAGEQGSPDTWRDVHGFALRFYTEEGNYDIV 140 Query: 142 YNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLT-TPENQVAIHQVMILFSDR 200 NNTP FF+RD KFP FIH+QKR + LRDADM WDF T PE + HQV L DR Sbjct: 141 GNNTPTFFLRDGMKFPDFIHSQKRLNKNGLRDADMQWDFWTRAPE---SAHQVTYLMGDR 197 Query: 201 GTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDYCQQ 260 GTP R G+ HT++W N G +V+ H KT QG T EA K+AG N DY ++ Sbjct: 198 GTPKTSRHQDGFGSHTFQWINAEGKPVWVKYHFKTRQGWDCFTDAEAAKVAGENADYQRE 257 Query: 261 DLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNENPL 320 DL+ AI+NG++P W V +Q M DA+ ++ FDLTK W Q +PL VG +LN NP Sbjct: 258 DLYNAIENGDFPIWDVKVQIMPFEDAENYRWNPFDLTKTWSQKDYPLIPVGYFILNRNPR 317 Query: 321 NFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNCPYASKF 380 NFFAQ+EQ A P VP S D +LQAR+F+YAD RYR+G N+ +PVN P Sbjct: 318 NFFAQIEQIALDPGNIVPGVGLSPDRMLQARIFAYADQQRYRIGANYRDLPVNRPINE-- 375 Query: 381 FNPAIRDGPMNVNGNFGSEPTYLAN--DKSYTYIQQDRPIQ-------QHQEVWNGP--- 428 N R+G M + EP+Y N DK Y+ Q +++ P Sbjct: 376 VNTYSREGSMQYIFDAEGEPSYSPNRYDKGAGYLDNGTDSSSNHTSYGQADDIYVNPDPH 435 Query: 429 ---AIPYHWATSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDM 485 + + D DF+Q LYR + + G+++ LA NI ++G + RVYD Sbjct: 436 GTDLVRAAYVKHQDDDDFIQPGILYREVLDE-GEKERLADNISNAMQGISEATEPRVYDY 494 Query: 486 FARVDKGLSEAIKKVAEAKHA 506 + VD+ L +K++ K A Sbjct: 495 WNNVDENLGARVKELYLQKKA 515 >4QOP-A nrPDB Length = 491 Score = 369 bits (948), Expect = e-102, Method: Compositional matrix adjust. Identities = 202/481 (41%), Positives = 285/481 (59%), Gaps = 20/481 (4%) Query: 22 VTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAFGYFE 81 +T + G P+ + ++ G GP L DY+LI+ LAHF+RE IP+R HA G+GA+G FE Sbjct: 9 LTTNQGVPVGDNQNSRTAGHRGPSFLDDYHLIEKLAHFDRERIPERVVHARGAGAYGVFE 68 Query: 82 VTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNLDWV 141 V + + +A S+ GK+T RFSTV KGS +T+RDPRGFA KFYTEEGN D V Sbjct: 69 VENSMEKHTRAAFLSEEGKQTDVFVRFSTVIHPKGSPETLRDPRGFAVKFYTEEGNYDLV 128 Query: 142 YNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLT-TPENQVAIHQVMILFSDR 200 NN P+FFIRD KFP +H+ K +P TN++D D +WDF+T TPE + H + LFSD Sbjct: 129 GNNLPIFFIRDALKFPDMVHSLKPDPVTNIQDPDRYWDFMTLTPE---STHMLTWLFSDE 185 Query: 201 GTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDYCQQ 260 G PANY M G HT++W NK G+ YV+ H + +GI+NL++EEA +I ++ + + Sbjct: 186 GIPANYAEMRGSGVHTFRWVNKYGETKYVKYHWRPSEGIRNLSMEEAAEIQANDFQHATR 245 Query: 261 DLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNENPL 320 DL++ I+ GNYP+W +Y+Q M D +L + D TK W + +PL++VG++ LN NP Sbjct: 246 DLYDRIEKGNYPAWDLYVQLMPLSDYDELDYDPCDPTKTWSEEDYPLQKVGRMTLNRNPE 305 Query: 321 NFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNCPYASKF 380 NFFA+ EQAAF PS VP EAS D +LQ RLFSY D R+RLG N+ +IPVNCPYA Sbjct: 306 NFFAETEQAAFTPSALVPGIEASEDKLLQGRLFSYPDTQRHRLGANYMRIPVNCPYAPVH 365 Query: 381 FNPAIRDGPMNV---NGNFGSEPT-YLANDKSYTYIQQDRPIQQHQEVWNGPAIPYHWAT 436 N +DG M +G+ EP Y K + ++ P V +G + Sbjct: 366 NNQ--QDGFMTTTRPSGHINYEPNRYDDQPKENPHYKESEP------VLHGDRMVRQKIE 417 Query: 437 SPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFARVDKGLSEA 496 P DF QA YR ++ +++ L N+ ++G + + F R D+ + Sbjct: 418 KPN--DFKQAGEKYRSYSEE--EKQALIKNLTADLKGVNEKTKLLAICNFYRADEDYGQR 473 Query: 497 I 497 + Sbjct: 474 L 474 >1GWF-A nrPDB Length = 503 Score = 366 bits (940), Expect = e-101, Method: Compositional matrix adjust. Identities = 204/477 (42%), Positives = 280/477 (58%), Gaps = 10/477 (2%) Query: 23 TNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAFGYFEV 82 T G P + +G GP++L D +L+++ HFNR NIP+R PHA GSGAFG FEV Sbjct: 14 TRQNGAPAVSDRQSLTVGSEGPIVLHDTHLLETHQHFNRMNIPERRPHAKGSGAFGEFEV 73 Query: 83 TDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNLDWVY 142 T+D++ + +F + G +T+ L RFSTV G+ GS DT RD RGFA +FYTEEGN D V Sbjct: 74 TEDVSKYTKALVF-QPGTKTETLLRFSTVAGELGSPDTWRDVRGFALRFYTEEGNYDLVG 132 Query: 143 NNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVMILFSDRGT 202 NNTP+FF+RDP KF HFI +QKR P + LRDA M WDF T N + HQV L RG Sbjct: 133 NNTPIFFLRDPMKFTHFIRSQKRLPDSGLRDATMQWDFWTN--NPESAHQVTYLMGPRGL 190 Query: 203 PANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDYCQQDL 262 P +R M+GY HTY W N G+ H+V+ H + QG+ NL+ +EATKIAG N D+ +QDL Sbjct: 191 PRTWREMNGYGSHTYLWVNAQGEKHWVKYHFISQQGVHNLSNDEATKIAGENADFHRQDL 250 Query: 263 FEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNENPLNF 322 FE+I G++P W +YIQ + + K F+ FDLTK Q +P +VG + LN NP N Sbjct: 251 FESIAKGDHPKWDLYIQAIPYEEGKTYRFNPFDLTKTISQKDYPRIKVGTLTLNRNPENH 310 Query: 323 FAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNCPYASKFFN 382 FAQ+E AAF+PS TVP S D +L R F+Y DA YR+G + +Q+PVN P + N Sbjct: 311 FAQIESAAFSPSNTVPGIGLSPDRMLLGRAFAYHDAQLYRVGAHVNQLPVNRP-KNAVHN 369 Query: 383 PAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGPAIPYHWATSPGDVD 442 A +G M + + G TY+ N ++ + P+ E +G A D D Sbjct: 370 YAF-EGQMWYD-HTGDRSTYVPNSNGDSWSDETGPVDDGWEA-DGTLTREAQALRADDDD 426 Query: 443 FVQARNLYR-VLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFARVDKGLSEAIK 498 F QA L R V Q ++ + + ++G +Q R ++ + VD + + I+ Sbjct: 427 FGQAGTLVREVFSDQ--ERDDFVETVAGALKGVRQDVQARAFEYWKNVDATIGQRIE 481 >2J2M-A nrPDB Length = 491 Score = 327 bits (838), Expect = 7e-90, Method: Compositional matrix adjust. Identities = 157/373 (42%), Positives = 232/373 (62%), Gaps = 6/373 (1%) Query: 19 DRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAFG 78 ++ +T + G PI + ++ G GP LL+DY LI+ +AHF+RE +P+R HA G GA G Sbjct: 5 EKKLTTNQGVPIGDNQNSRTAGRRGPTLLEDYQLIEKIAHFDRERVPERVVHARGFGAHG 64 Query: 79 YFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNL 138 F+V + + +A + G RFSTV S +T+RDPRGF+ KFYTEEGN Sbjct: 65 VFKVKNSMKKYTKAAFLQEEGTEVPVFARFSTVIHGTHSPETLRDPRGFSVKFYTEEGNW 124 Query: 139 DWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTT-PENQVAIHQVMILF 197 D+V NN PVFFIRD KFP +H+ K +P+TN++D D +WDF+T PE + + +M +F Sbjct: 125 DFVGNNLPVFFIRDAMKFPDMVHSLKPDPRTNIQDPDRYWDFMTLRPE---STNMLMHIF 181 Query: 198 SDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDY 257 +D G PA+YR M G S H++KW N +G+ Y+++ +G+ NL+ +EAT++ G + ++ Sbjct: 182 TDEGIPASYRKMRGSSVHSFKWVNAHGNTVYIKLRWVPKEGVHNLSADEATEVQGKDFNH 241 Query: 258 CQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNE 317 D F+AI+NG++P W +++Q + D + F D TK W + P + VG + LN+ Sbjct: 242 ASNDTFQAIENGDFPEWDLFVQVLDPADVENFDFDPLDATKDWFEDVIPFQHVGTMTLNK 301 Query: 318 NPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNCPYA 377 N N+FA+ E F P VP S D +LQ RLFSY+D R+R+GPN+ Q+P+NCP+A Sbjct: 302 NVDNYFAETESVGFNPGVLVPGMLPSEDKLLQGRLFSYSDTQRHRIGPNYQQLPINCPFA 361 Query: 378 SKFFNPAIRDGPM 390 N RDG M Sbjct: 362 Q--VNNYQRDGAM 372 >4CAB-A nrPDB Length = 536 Score = 323 bits (827), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 185/506 (36%), Positives = 274/506 (54%), Gaps = 41/506 (8%) Query: 21 VVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAFGYF 80 +T G+P+++ ++ +G GP+ L++Y I+ L+HF+RE IP+R HA G GA G F Sbjct: 32 TLTTRQGHPVHDNQNSRTVGSRGPMTLENYQFIEKLSHFDRERIPERVVHARGVGAHGVF 91 Query: 81 EVTDDITD-----ICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEE 135 T + D + +F + GK T RFSTVG S +T+RDPRGFA KFYTE+ Sbjct: 92 RATGKVGDEPVSKYTRAKLFQEDGKETPVFVRFSTVGHGTHSPETLRDPRGFAVKFYTED 151 Query: 136 GNLDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLT-TPENQVAIHQVM 194 GN D V NN +FFIRD KFP IH+QK +P TN++ + +DF +PE A H + Sbjct: 152 GNWDLVGNNLKIFFIRDALKFPDLIHSQKPSPTTNIQSQERIFDFFAGSPE---ATHMIT 208 Query: 195 ILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSN 254 +L+S G PA+YR M G +TYKW N G+ V+ H + QG++NLT +A ++ +N Sbjct: 209 LLYSPWGIPASYRFMQGSGVNTYKWVNDQGEGVLVKYHWEPVQGVRNLTQMQADEVQATN 268 Query: 255 PDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIV 314 ++ QDL +AI+ G++P W +++Q M + + +L F D TK+WP+ QFP R VG++ Sbjct: 269 FNHATQDLHDAIERGDFPQWDLFVQIMEDGEHPELDFDPLDDTKIWPREQFPWRHVGQMT 328 Query: 315 LNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNC 374 LN NP N FA+ EQAAF V + S D +LQ R FSY+D RYR+GPN+ Q+P+N Sbjct: 329 LNRNPENVFAETEQAAFGTGVLVDGLDFSDDKMLQGRTFSYSDTQRYRVGPNYLQLPINA 388 Query: 375 PYASKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGPA----- 429 P K RDG M Y + T+ QD+ + + +GP Sbjct: 389 P--KKHVATNQRDGQM----------AYRVD----TFEGQDQRVNYEPSLLSGPKEAPRR 432 Query: 430 IPYHWATSPGDV---------DFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQIQQ 480 P H G++ F QA YR ++ L N+ + G +IQ Sbjct: 433 APEHTPRVEGNLVRAAIERPNPFGQAGMQYRNFADW--ERDELVSNLSGALAGVDKRIQD 490 Query: 481 RVYDMFARVDKGLSEAIKKVAEAKHA 506 ++ + F D + +++ +AK A Sbjct: 491 KMLEYFTAADADYGQRVREGIQAKEA 516 >3TTT-A nrPDB Length = 753 Score = 318 bits (814), Expect = 5e-87, Method: Compositional matrix adjust. Identities = 197/507 (38%), Positives = 281/507 (55%), Gaps = 32/507 (6%) Query: 12 NYSDVR---EDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRN 68 + DVR E+ +T + G I + + R G GP LL+D+ L + + HF+ E IP+R Sbjct: 67 SLEDVRKGSENYALTTNQGVRIADDQNSLRAGSRGPTLLEDFILREKITHFDHERIPERI 126 Query: 69 PHAHGSGAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFA 128 HA GS A GYF+ ++DI + S K T RFSTV G GSADTVRD RGFA Sbjct: 127 VHARGSAAHGYFQPYKSLSDITKADFLSDPNKITPVFVRFSTVQGGAGSADTVRDIRGFA 186 Query: 129 TKFYTEEGNLDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDA----DMFWDFLTT- 183 TKFYTEEG D V NNTP+FFI+D KFP F+H K P + D FWD+++ Sbjct: 187 TKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFVHAVKPEPHWAIPQGQSAHDTFWDYVSLQ 246 Query: 184 PENQVAIHQVMILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLT 243 PE +H VM SDRG P +YR+M G+ HT++ N G +V+ H K G +L Sbjct: 247 PET---LHNVMWAMSDRGIPRSYRTMEGFGIHTFRLINAEGKATFVRFHWKPLAGKASLV 303 Query: 244 IEEATKIAGSNPDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQG 303 +EA K+ G +PD+ +++L+EAI+ G++P + + Q + E D K F + D TK+ P+ Sbjct: 304 WDEAQKLTGRDPDFHRRELWEAIEAGDFPEYELGFQLIPEEDEFKFDFDLLDPTKLIPEE 363 Query: 304 QFPLRRVGKIVLNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRL 363 P++RVGK+VLN NP NFFA+ EQAAF P VP + + DP+LQ RL+SY D RL Sbjct: 364 LVPVQRVGKMVLNRNPDNFFAENEQAAFHPGHIVPGLDFTNDPLLQGRLYSYTDTQISRL 423 Query: 364 -GPNFHQIPVN---CPYASKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRP-- 417 GPNFH+IP+N CPY + F RDG M+ G + Y N + + ++ P Sbjct: 424 GGPNFHEIPINRPTCPYHN--FQ---RDG-MHRMGIDTNPANYEPNSINDNWPRETPPGP 477 Query: 418 ----IQQHQEVWNGPAIPYHWATSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEG 473 + +QE G + SP ++ L+ L + P +Q+++ + Sbjct: 478 KRGGFESYQERVEGNKV---RERSPSFGEYYSHPRLF-WLSQTPFEQRHIVDGFSFELSK 533 Query: 474 AC-PQIQQRVYDMFARVDKGLSEAIKK 499 P I++RV D A +D L++A+ K Sbjct: 534 VVRPYIRERVVDQLAHIDLTLAQAVAK 560 >1M7S-A nrPDB Length = 484 Score = 295 bits (756), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 157/373 (42%), Positives = 217/373 (58%), Gaps = 9/373 (2%) Query: 21 VVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAFGYF 80 +T G + + +Q G GP+LLQD L+ L F+RE IP+R HA G+G G F Sbjct: 3 TLTRDNGAVVGDNQNSQTAGAQGPVLLQDVQLLQKLQRFDRERIPERVVHARGTGVKGEF 62 Query: 81 EVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNLDW 140 + DI+D+ + +F K G++T RFS+V S +T+RDP GFATKFYT +GN D Sbjct: 63 TASADISDLSKATVF-KSGEKTPVFVRFSSVVHGNHSPETLRDPHGFATKFYTADGNWDL 121 Query: 141 VYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLT-TPENQVAIHQVMILFSD 199 V NN P FFIRD KFP +H K +P+TNL + +DF + PE A + +L+S+ Sbjct: 122 VGNNFPTFFIRDAIKFPDMVHAFKPDPRTNLDNDSRRFDFFSHVPE---ATRTLTLLYSN 178 Query: 200 RGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDYCQ 259 GTPA YR M G H YK N G+ HYV+ H K+ QGIKNL +E ++ + + Sbjct: 179 EGTPAGYRFMDGNGVHAYKLVNAKGEVHYVKFHWKSLQGIKNLDPKEVAQVQSKDYSHLT 238 Query: 260 QDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNENP 319 DL AI+ G++P W +Y+Q + + K F D TK+WP P +++G++VLN+N Sbjct: 239 NDLVGAIKKGDFPKWDLYVQVLKPEELAKFDFDPLDATKIWP--DVPEKKIGQMVLNKNV 296 Query: 320 LNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNCPYASK 379 NFF + EQ A AP+ VP E S D +LQ R+FSYAD YRLG N +PVN P + Sbjct: 297 DNFFQETEQVAMAPANLVPGIEPSEDRLLQGRVFSYADTQMYRLGANGLSLPVNQPKVA- 355 Query: 380 FFNPAIRDGPMNV 392 N +DG +N Sbjct: 356 -VNNGNQDGALNT 367 >1SY7-A nrPDB Length = 715 Score = 289 bits (739), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 177/475 (37%), Positives = 248/475 (52%), Gaps = 36/475 (7%) Query: 43 GPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAFGYFEVTDDITDICGSAMFSKIGKRT 102 GP LL+D + + F+ E IP+R HA GSGAFG F+V + +D+ + + + + T Sbjct: 44 GPSLLEDPFARERIMRFDHERIPERVVHARGSGAFGKFKVYESASDLTMAPVLTDTSRET 103 Query: 103 KCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNLDWVYNNTPVFFIRDPSKFPHFIHT 162 RFSTV G +GSADTVRD RGFA KFYTEEGN D V NN PVFFI+D KFP IH Sbjct: 104 PVFVRFSTVLGSRGSADTVRDVRGFAVKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHA 163 Query: 163 QKRNPQTNLRDA----DMFWDFLTTPENQVAIHQVMILFSDRGTPANYRSMHGYSGHTYK 218 K P + A + FWDF + A H SDR P + R M G+ +TY Sbjct: 164 GKPEPHNEVPQAQSAHNNFWDFQFN--HTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYT 221 Query: 219 WSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDYCQQDLFEAIQNGNYPSWTVYI 278 N G H+V+ H + G+ +L +EA K+AG +PD+ ++DL+EAI+NG YP W I Sbjct: 222 LINAQGKRHFVKFHWTPELGVHSLVWDEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGI 281 Query: 279 QTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNENPLNFFAQVEQAAFAPSTTVP 338 Q + E D K F + D TK+WP+ P+R +G++ LN NP FF Q EQ AF S V Sbjct: 282 QAIAEEDEHKFDFDILDATKIWPEDLVPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVN 341 Query: 339 YQEASADPVLQARLFSYADAHRYRLGPNFHQIPVN---CPYASKFFNPAIRDGPMNVNGN 395 S DP+LQ R FSY D RLG NF ++P+N CP + FN RDG M + Sbjct: 342 GIGFSDDPLLQGRNFSYFDTQISRLGVNFQELPINRPVCPVMN--FN---RDGAMRHTIS 396 Query: 396 FGSEPTY--------LANDKSYTYIQQDRPIQQHQEVWNGPAIPYHWATSPGDVDFVQAR 447 G+ Y A+ K Y++ + + + H F QA+ Sbjct: 397 RGTVNYYPNRFDACPPASLKEGGYLEYAQKVAGIKARARSAKFKEH---------FSQAQ 447 Query: 448 NLYRVLGKQPGQQKNLAYNIGIHVEGAC--PQIQQRVYDMFARVDKGLSEAIKKV 500 Y + P +++++ G ++ C P + R+ A +D GL++ I ++ Sbjct: 448 LFYNSM--SPIEKQHMINAFGFELD-HCEDPVVYGRMVQRLADIDLGLAQTIAEM 499 >4BIM-A nrPDB Length = 746 Score = 281 bits (720), Expect = 4e-76, Method: Compositional matrix adjust. Identities = 167/440 (37%), Positives = 240/440 (54%), Gaps = 26/440 (5%) Query: 6 QEKNEVNYSDVREDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIP 65 Q EV D + +T G I E F + + G G LL+D+ L HF+ E IP Sbjct: 68 QRLKEVEVDD--NGQFMTTDFGGNIEEQF-SLKAGGRGSTLLEDFIFRQKLQHFDHERIP 124 Query: 66 QRNPHAHGSGAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPR 125 +R HA G+GA G F D ++I ++ K+T RFSTV G +GSADT RD Sbjct: 125 ERVVHARGAGAHGIFTSYGDWSNITAASFLGAKDKQTPVFVRFSTVAGSRGSADTARDVH 184 Query: 126 GFATKFYTEEGNLDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDA----DMFWDFL 181 GFAT+FYT+EGN D V NN PVFFI+D +FP IH+ K +P + A D WDF Sbjct: 185 GFATRFYTDEGNFDIVGNNIPVFFIQDAIRFPDLIHSVKPSPDNEVPQAATAHDSAWDFF 244 Query: 182 TTPENQVAIHQVMILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKN 241 ++ + A+H + S G P +YR M G+ HT++ ++G V+ H KT QG Sbjct: 245 SSQPS--ALHTLFWAMSGNGIPRSYRHMDGFGIHTFRLVTEDGKSKLVKWHWKTKQGKAA 302 Query: 242 LTIEEATKIAGSNPDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWP 301 L EEA +AG N D+ +QDL++AI++GN PSW + +Q + E A+ F + D TK P Sbjct: 303 LVWEEAQVLAGKNADFHRQDLWDAIESGNAPSWELAVQLIDEDKAQAYGFDLLDPTKFLP 362 Query: 302 QGQFPLRRVGKIVLNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADA--H 359 + PL+ +G++ LN NP+N+FA+ EQ +F P V + + DP+LQ RL+SY D + Sbjct: 363 EEFAPLQVLGEMTLNRNPMNYFAETEQISFQPGHIVRGVDFTEDPLLQGRLYSYLDTQLN 422 Query: 360 RYRLGPNFHQIPVNCPYASKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQ 419 R+R GPNF Q+P+N P + N G ++ N + S +Y+ + P Q Sbjct: 423 RHR-GPNFEQLPINRPVSGVHNNHRDGQGQAWIHKNI--------HHYSPSYLNKGYPAQ 473 Query: 420 QHQEVWNGPAIPYHWATSPG 439 +Q V G + T+PG Sbjct: 474 ANQTVGRG------FFTTPG 487 >4B7A-A nrPDB Length = 719 Score = 280 bits (716), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 144/359 (40%), Positives = 208/359 (57%), Gaps = 8/359 (2%) Query: 22 VTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAFGYFE 81 +T+ G PI + + + G GP LL+D+ + HF+ E +P+R HA G+GA G F Sbjct: 56 LTSDVGGPIQDQ-TSLKAGIRGPTLLEDFMFRQKIQHFDHERVPERAVHARGAGAHGTFT 114 Query: 82 VTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNLDWV 141 D ++I ++ + GK+T RFSTV G +GSADT RD GFAT+FYT+EGN D V Sbjct: 115 SYADWSNITAASFLNATGKQTPVFVRFSTVAGSRGSADTARDVHGFATRFYTDEGNFDIV 174 Query: 142 YNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDA----DMFWDFLTTPENQVAIHQVMILF 197 NN PVFFI+D +FP IH+ K P + A D WDF + + +H + Sbjct: 175 GNNIPVFFIQDAIQFPDLIHSVKPRPDNEIPQAATAHDSAWDFFS--QQPSTMHTLFWAM 232 Query: 198 SDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDY 257 S G P +YR M G+ HT+++ +G ++ H K+ QG +L EEA ++G N D+ Sbjct: 233 SGHGIPRSYRHMDGFGVHTFRFVKDDGSSKLIKWHFKSRQGKASLVWEEAQVLSGKNADF 292 Query: 258 CQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNE 317 +QDL++AI++GN P W V +Q + E A+ F + D TK+ P+ PL ++G + L+ Sbjct: 293 HRQDLWDAIESGNGPEWDVCVQIVDESQAQAFGFDLLDPTKIIPEEYAPLTKLGLLKLDR 352 Query: 318 NPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYR-LGPNFHQIPVNCP 375 NP N+FA+ EQ F P V + + DP+LQ RLFSY D R GPNF Q+P+N P Sbjct: 353 NPTNYFAETEQVMFQPGHIVRGIDFTEDPLLQGRLFSYLDTQLNRNGGPNFEQLPINMP 411 >2IUF-A nrPDB Length = 688 Score = 277 bits (709), Expect = 7e-75, Method: Compositional matrix adjust. Identities = 145/365 (39%), Positives = 208/365 (56%), Gaps = 8/365 (2%) Query: 18 EDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAF 77 +D +T++ G PI + + G+ G LLQD+ + + F+ E +P+R HA G+GA Sbjct: 12 QDVYLTSNVGGPIQDE-NSLSAGQRGATLLQDFIFREKIQRFDHERVPERAVHARGTGAH 70 Query: 78 GYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGN 137 G F D +++ ++ S GK T TRFSTV G +GSADT RD GFAT+FYT+EGN Sbjct: 71 GTFTSYGDWSNLTAASFLSAEGKETPMFTRFSTVAGSRGSADTARDVHGFATRFYTDEGN 130 Query: 138 LDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDA----DMFWDFLTTPENQVAIHQV 193 D V NN PVFFI+D FP IH K + A D WDF + + +H + Sbjct: 131 FDIVGNNIPVFFIQDAILFPDLIHAVKPRGDNQIPQAATAHDSAWDFFS--QQPSVLHTL 188 Query: 194 MILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGS 253 + + G P ++R ++G+ HT++ +G V+ H K QG + EEA + AG Sbjct: 189 LWAMAGHGIPRSFRHVNGFGVHTFRLVTDDGKTKLVKFHWKGLQGKASFVWEEAQQTAGK 248 Query: 254 NPDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKI 313 N D+ +QDLF++IQ G +P W + +Q M E+D K F + D TK+ P+ P+ +GK+ Sbjct: 249 NADFMRQDLFQSIQAGRFPEWELGVQIMQEQDQLKFGFDLLDPTKIVPEELVPVTILGKM 308 Query: 314 VLNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRL-GPNFHQIPV 372 LN NP+N+FA+ EQ F P V + + DP+LQ RLFSY D R GPNF Q+P+ Sbjct: 309 QLNRNPMNYFAETEQVMFQPGHIVRGVDFTEDPLLQGRLFSYLDTQLNRHGGPNFEQLPI 368 Query: 373 NCPYA 377 N P A Sbjct: 369 NRPRA 373 >1YE9-A nrPDB Length = 226 Score = 181 bits (458), Expect = 8e-46, Method: Compositional matrix adjust. Identities = 100/226 (44%), Positives = 130/226 (57%), Gaps = 8/226 (3%) Query: 18 EDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAF 77 E+ +T + G I + + R G GP LL+D+ L + + HF+ E IP+R HA GS A Sbjct: 2 ENYALTTNQGVRIADDQNSLRAGSRGPTLLEDFILREKITHFDHERIPERIVHARGSAAH 61 Query: 78 GYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGN 137 GYF+ ++DI + S K T RFSTV G GSADTVRD RGFATKFYTEEG Sbjct: 62 GYFQPYKSLSDITKADFLSDPNKITPVFVRFSTVQGGAGSADTVRDIRGFATKFYTEEGI 121 Query: 138 LDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDA----DMFWDFLTT-PENQVAIHQ 192 D V NNTP+FFI+D KFP F+H K P + D FWD+++ PE +H Sbjct: 122 FDLVGNNTPIFFIQDAHKFPDFVHAVKPEPHWAIPQGQSAHDTFWDYVSLQPET---LHN 178 Query: 193 VMILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQG 238 VM SDRG P +YR+M G+ HT++ N G +V+ H K G Sbjct: 179 VMWAMSDRGIPRSYRTMEGFGIHTFRLINAEGKATFVRFHWKPLAG 224 >1YE9-E nrPDB Length = 259 Score = 137 bits (346), Expect = 8e-33, Method: Compositional matrix adjust. Identities = 91/262 (34%), Positives = 141/262 (53%), Gaps = 21/262 (8%) Query: 249 KIAGSNPDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLR 308 K+ G +PD+ +++L+EAI+ G++P + + Q + E D K F + D TK+ P+ P++ Sbjct: 1 KLTGRDPDFHRRELWEAIEAGDFPEYELGFQLIPEEDEFKFDFDLLDPTKLIPEELVPVQ 60 Query: 309 RVGKIVLNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRL-GPNF 367 RVGK+VLN NP NFFA+ EQAAF P VP + + DP+LQ RLFSY D RL GPNF Sbjct: 61 RVGKMVLNRNPDNFFAENEQAAFHPGHIVPGLDFTNDPLLQGRLFSYTDTQISRLGGPNF 120 Query: 368 HQIPVN---CPYASKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRP------I 418 H+IP+N CPY + RDG M+ G + Y N + + ++ P Sbjct: 121 HEIPINRPTCPYHN-----FQRDG-MHRMGIDTNPANYEPNSINDNWPRETPPGPKRGGF 174 Query: 419 QQHQEVWNGPAIPYHWATSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGAC-PQ 477 + +QE G + SP ++ L+ L + P +Q+++ + P Sbjct: 175 ESYQERVEGNKV---RERSPSFGEYYSHPRLF-WLSQTPFEQRHIVDGFSFELSKVVRPY 230 Query: 478 IQQRVYDMFARVDKGLSEAIKK 499 I++RV D A +D L++A+ K Sbjct: 231 IRERVVDQLAHIDLTLAQAVAK 252 >3E4Y-A nrPDB Length = 320 Score = 60.1 bits (144), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 68/299 (22%), Positives = 109/299 (36%), Gaps = 21/299 (7%) Query: 67 RNPHAHGSGAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRG 126 R HA G+ G F T D + + G L RFS G+ D RG Sbjct: 32 RALHAKGTLYRGTFTATRDAVMLSAAPHLD--GSTVPALIRFSNGSGNPKQRDGAPGVRG 89 Query: 127 FATKFYTEEGNLDWVYNNTPVFFIRD-PSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPE 185 A KF +G+ V T + P F + + T LR + LT P Sbjct: 90 MAVKFTLPDGSTTDVSAQTARLLVSSTPEGFIDLLKAMRPGLTTPLR---LATHLLTHPR 146 Query: 186 NQVAIHQVMILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIE 245 + + +L PA+Y + + H ++W +G +V+ H+ + L+ Sbjct: 147 ---LLGALPLLREANRIPASYATTEYHGLHAFRWIAADGSARFVRYHLVPTAAEEYLSAS 203 Query: 246 EATKIAGSNPDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQF 305 +A G +PD+ +L +Q+G + +Q D S D + W Q Sbjct: 204 DAR---GKDPDFLTDELAARLQDGPV-RFDFRVQIAGPTD------STVDPSSAWQSTQ- 252 Query: 306 PLRRVGKIVLNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLG 364 + VG + + + F P E S DPVL+ R Y+ + + R G Sbjct: 253 -IVTVGTVTITGPDTEREHGGDIVVFDPMRVTDGIEPSDDPVLRFRTLVYSASVKLRTG 310 >6DFZ-A nrPDB Length = 332 Score = 35.0 bits (79), Expect = 0.085, Method: Compositional matrix adjust. Identities = 24/85 (28%), Positives = 43/85 (50%), Gaps = 16/85 (18%) Query: 311 GKIVLNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQAR-LFSYADAHRYRLGPNFHQ 369 GK+V+N NP++ +A + AA +P++EA AD V+++ +F+ + L + Sbjct: 62 GKLVINGNPISVYALKDPAA------IPWKEAGADFVVESTGVFTTTEKASAHLHGGAKK 115 Query: 370 IPVNCPYASKFFNPAIRDGPMNVNG 394 + ++ P A D PM V G Sbjct: 116 VIISAPSA---------DAPMFVMG 131 >3P56-A nrPDB Length = 299 Score = 32.3 bits (72), Expect = 0.58, Method: Compositional matrix adjust. Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 3/59 (5%) Query: 156 FPHFIHTQKRNPQTNLRDA--DMFWDFLTTPENQVAIHQVMILFSDRGTPANYRSMHGY 212 FP F+ R QT L D+ W+ + ENQ + ++ F + G+ A RS H Y Sbjct: 230 FPQFVRFSWRTAQTILEKEAEDVIWED-SASENQEGLRKITSYFLNEGSQARPRSSHRY 287 >2HW6-A nrPDB Length = 307 Score = 30.4 bits (67), Expect = 1.9, Method: Compositional matrix adjust. Identities = 21/60 (35%), Positives = 25/60 (41%), Gaps = 11/60 (18%) Query: 258 CQQDLFEAIQNGNY----PSWT-------VYIQTMTERDAKKLPFSVFDLTKVWPQGQFP 306 CQ LFE+IQ G Y W I + RDAK+ + L W QGQ P Sbjct: 245 CQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAP 304 >1F1U-A nrPDB Length = 323 Score = 30.4 bits (67), Expect = 2.0, Method: Compositional matrix adjust. Identities = 27/109 (24%), Positives = 44/109 (40%), Gaps = 7/109 (6%) Query: 53 IDSLAHFNRENIPQRNPHAHGSGAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVG 112 + SL F N+ R AF Y + D A + ++G C T G Sbjct: 53 LRSLEEFIHHNLVLRQGPIAAVAAFAYRVKSPAEVD-AAEAYYKELG----CRTERRKEG 107 Query: 113 GDKGSADTVR--DPRGFATKFYTEEGNLDWVYNNTPVFFIRDPSKFPHF 159 KG D+VR DP GF +F+ E +++ + ++ + + HF Sbjct: 108 FTKGIGDSVRVEDPLGFPYEFFYETEHVERLTQRYDLYSAGELVRLDHF 156 >2GJP-A nrPDB Length = 485 Score = 29.3 bits (64), Expect = 4.1, Method: Compositional matrix adjust. Identities = 13/30 (43%), Positives = 19/30 (63%), Gaps = 1/30 (3%) Query: 333 PSTTVPYQEASADPVLQARL-FSYADAHRY 361 P+ +VP +A DP+L+AR F+Y H Y Sbjct: 375 PTHSVPAMKAKIDPILEARQNFAYGTQHDY 404 >4UXR-C nrPDB Length = 375 Score = 29.3 bits (64), Expect = 4.8, Method: Compositional matrix adjust. Identities = 18/71 (25%), Positives = 34/71 (47%), Gaps = 3/71 (4%) Query: 433 HWA-TSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFARVDK 491 +W+ TSP D+++ + +YR +G++ Q YN+ I G + Y M + +K Sbjct: 62 YWSHTSPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTG--AGKSYTMMGKQEK 119 Query: 492 GLSEAIKKVAE 502 I ++ E Sbjct: 120 DQQGIIPQLCE 130 >6GN6-A nrPDB Length = 447 Score = 28.1 bits (61), Expect = 8.9, Method: Compositional matrix adjust. Identities = 13/51 (25%), Positives = 24/51 (47%) Query: 432 YHWATSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQIQQRV 482 +HW D D+ + + R L + + N+ N+G + +G PQ+ V Sbjct: 286 HHWGYHAHDRDYKTPKQVVRGLVECVSKNGNMLLNVGPNAKGEIPQLSLDV 336 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1A4E-A nrPDB 720 0.0 5GKN-A nrPDB 701 0.0 1QQW-A nrPDB 700 0.0 3HB6-A nrPDB 697 0.0 2ISA-A nrPDB 695 0.0 2XQ1-A nrPDB 691 0.0 4E37-A nrPDB 683 0.0 3TTT-A nrPDB 674 0.0 2IQF-A nrPDB 673 0.0 1SI8-A nrPDB 663 0.0 4QOP-A nrPDB 661 0.0 4B7G-A nrPDB 634 0.0 4CAB-A nrPDB 631 0.0 4BIM-A nrPDB 623 e-179 1GWF-A nrPDB 623 e-179 2J2M-A nrPDB 620 e-178 4B7A-A nrPDB 604 e-173 1SY7-A nrPDB 602 e-172 2IUF-A nrPDB 589 e-168 1M7S-A nrPDB 579 e-166 1YE9-A nrPDB 355 2e-98 3E4Y-A nrPDB 313 1e-85 1YE9-E nrPDB 301 6e-82 Sequences not found previously or not previously below threshold: 1U5U-A nrPDB 55 7e-08 5WQK-A nrPDB 35 0.097 2W8Z-A nrPDB 34 0.18 4OUA-B nrPDB 32 0.57 4GI8-A nrPDB 32 0.61 1X53-A nrPDB 32 0.71 2J63-A nrPDB 32 0.90 2DIE-A nrPDB 31 1.0 4GGP-A nrPDB 31 1.6 5U5I-A nrPDB 31 1.6 2PNC-A nrPDB 30 1.8 1M53-A nrPDB 30 2.1 4CNR-A nrPDB 30 2.2 4GFV-A nrPDB 30 2.7 1U10-A nrPDB 30 2.9 4CN6-A nrPDB 29 3.9 1YWQ-A nrPDB 29 4.6 1PHO-A nrPDB 29 5.6 2F3T-A nrPDB 29 5.7 >1A4E-A nrPDB Length = 488 Score = 720 bits (1859), Expect = 0.0, Method: Composition-based stats. Identities = 488/488 (100%), Positives = 488/488 (100%) Query: 15 DVREDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGS 74 DVREDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGS Sbjct: 1 DVREDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGS 60 Query: 75 GAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTE 134 GAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTE Sbjct: 61 GAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTE 120 Query: 135 EGNLDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVM 194 EGNLDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVM Sbjct: 121 EGNLDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVM 180 Query: 195 ILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSN 254 ILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSN Sbjct: 181 ILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSN 240 Query: 255 PDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIV 314 PDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIV Sbjct: 241 PDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIV 300 Query: 315 LNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNC 374 LNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNC Sbjct: 301 LNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNC 360 Query: 375 PYASKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGPAIPYHW 434 PYASKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGPAIPYHW Sbjct: 361 PYASKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGPAIPYHW 420 Query: 435 ATSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFARVDKGLS 494 ATSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFARVDKGLS Sbjct: 421 ATSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFARVDKGLS 480 Query: 495 EAIKKVAE 502 EAIKKVAE Sbjct: 481 EAIKKVAE 488 >5GKN-A nrPDB Length = 527 Score = 701 bits (1809), Expect = 0.0, Method: Composition-based stats. Identities = 248/509 (48%), Positives = 320/509 (62%), Gaps = 25/509 (4%) Query: 21 VVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAFGYF 80 V+T GNP+ + + +G GPLL+QD D +AHF+RE IP+R HA G+GAFGYF Sbjct: 26 VLTTGGGNPVGDKLNSLTVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYF 85 Query: 81 EVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNLDW 140 EVT DIT + +F IGKRT RFSTV G+ GSADTVRDPRGFA KFYTE+GN D Sbjct: 86 EVTHDITRYSKAKVFEHIGKRTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDL 145 Query: 141 VYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVMILFSDR 200 V NNTP+FFIRD FP FIH+QKRNPQT+L+D DM WDF + ++HQV LFSDR Sbjct: 146 VGNNTPIFFIRDALLFPSFIHSQKRNPQTHLKDPDMVWDFWSL--RPESLHQVSFLFSDR 203 Query: 201 GTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDYCQQ 260 G P +R M+GY HT+K N NG+ Y + H KTDQGIKNL++E+A ++A +PDY + Sbjct: 204 GIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLAHEDPDYGLR 263 Query: 261 DLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNENPL 320 DLF AI GNYPSWT+YIQ MT +A+ PF+ FDLTKVWP G +PL VGK+VLN NP+ Sbjct: 264 DLFNAIATGNYPSWTLYIQVMTFSEAEIFPFNPFDLTKVWPHGDYPLIPVGKLVLNRNPV 323 Query: 321 NFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNCPYASKF 380 N+FA+VEQ AF PS P E S D +LQ RLF+Y D HR+RLGPN+ QIPVNCPY ++ Sbjct: 324 NYFAEVEQLAFDPSNMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVNCPYRARV 383 Query: 381 FNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGPAIPYHWATSPGD 440 N RDGPM + N G P Y N S++ + +H+ ++G + S D Sbjct: 384 AN-YQRDGPMCMMDNQGGAPNYYPN--SFSAPEHQPSALEHRTHFSGDVQRF---NSAND 437 Query: 441 VDFVQARNLY-RVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFARVDKGLSEAIKK 499 + Q R Y +VL ++ Q+K L NI H++ A IQ++ F+ V I+ Sbjct: 438 DNVTQVRTFYLKVLNEE--QRKRLCENIAGHLKDAQLFIQKKAVKNFSDVHPEYGSRIQA 495 Query: 500 VAEA--------------KHASELSSNSK 514 + + +H S LS+ K Sbjct: 496 LLDKYNEEKPKNAVHTYVQHGSHLSAREK 524 >1QQW-A nrPDB Length = 527 Score = 700 bits (1807), Expect = 0.0, Method: Composition-based stats. Identities = 241/489 (49%), Positives = 309/489 (63%), Gaps = 11/489 (2%) Query: 21 VVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAFGYF 80 V+T GNP+ + +G GPLL+QD D +AHF+RE IP+R HA G+GAFGYF Sbjct: 26 VLTTGAGNPVGDKLNVITVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYF 85 Query: 81 EVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNLDW 140 EVT DIT + +F IGK+T RFSTV G+ GSADTVRDPRGFA KFYTE+GN D Sbjct: 86 EVTHDITKYSKAKVFEHIGKKTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDL 145 Query: 141 VYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVMILFSDR 200 V NNTP+FFIRDP FP FIH+QKRNPQT+L+D DM WDF + ++HQV LFSDR Sbjct: 146 VGNNTPIFFIRDPILFPSFIHSQKRNPQTHLKDPDMVWDFWSL--RPESLHQVSFLFSDR 203 Query: 201 GTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDYCQQ 260 G P +R M+GY HT+K N NG+ Y + H KTDQGIKNL++E+A +++ +PDY + Sbjct: 204 GIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLSQEDPDYGIR 263 Query: 261 DLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNENPL 320 DLF AI G YPSWT YIQ MT A+ PF+ FDLTKVWP +PL VGK+VLN NP+ Sbjct: 264 DLFNAIATGKYPSWTFYIQVMTFNQAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNRNPV 323 Query: 321 NFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNCPYASKF 380 N+FA+VEQ AF PS P EAS D +LQ RLF+Y D HR+RLGPN+ IPVNCPY ++ Sbjct: 324 NYFAEVEQIAFDPSNMPPGIEASPDKMLQGRLFAYPDTHRHRLGPNYLHIPVNCPYRARV 383 Query: 381 FNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGPAIPYHWATSPGD 440 N RDGPM + N G P Y N S+ +Q +H ++G + + D Sbjct: 384 AN-YQRDGPMCMQDNQGGAPNYYPN--SFGAPEQQPSALEHSIQYSGEVRRF---NTAND 437 Query: 441 VDFVQARNLY-RVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFARVDKGLSEAIKK 499 + Q R Y VL ++ Q+K L NI H++ A IQ++ F V I+ Sbjct: 438 DNVTQVRAFYVNVLNEE--QRKRLCENIAGHLKDAQIFIQKKAVKNFTEVHPDYGSHIQA 495 Query: 500 VAEAKHASE 508 + + +A + Sbjct: 496 LLDKYNAEK 504 >3HB6-A nrPDB Length = 484 Score = 697 bits (1800), Expect = 0.0, Method: Composition-based stats. Identities = 219/492 (44%), Positives = 293/492 (59%), Gaps = 13/492 (2%) Query: 18 EDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAF 77 E + +T + G P+ + G GP+LLQD ++ LAHF+RE IP+R A GSGAF Sbjct: 2 EKKKLTTAAGAPVVDNNNVITAGPRGPMLLQDVWFLEKLAHFDREVIPERRMFAKGSGAF 61 Query: 78 GYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGN 137 G F VT DIT + +FS++GK+T+ RFSTV G++G+AD RD RGFA KFYTEEGN Sbjct: 62 GTFTVTHDITKYTRAKIFSEVGKKTEMFARFSTVAGERGAADAERDIRGFALKFYTEEGN 121 Query: 138 LDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVMILF 197 D V NNTPVF++RDP KFP H KR+P+TN+R+ WDF + ++HQ+ I Sbjct: 122 WDMVGNNTPVFYLRDPLKFPDLNHIVKRDPRTNMRNMAYKWDFFSH--LPESLHQLTIDM 179 Query: 198 SDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDY 257 SDRG P +YR +HG+ HTY + NK+ + +V+ H + QGIKNL +EA + G + + Sbjct: 180 SDRGLPLSYRFVHGFGSHTYSFINKDNERFWVKFHFRCQQGIKNLMDDEAEALVGKDRES 239 Query: 258 CQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNE 317 Q+DLFEAI+ G+YP W + IQ M E++A +P++ FDLTKVWP +PL VG LN Sbjct: 240 SQRDLFEAIERGDYPRWKLQIQIMPEKEASTVPYNPFDLTKVWPHADYPLMDVGYFELNR 299 Query: 318 NPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNCPYA 377 NP N+F+ VEQAAF+P+ VP S D +LQ RLFSY DAHRYRLG N HQIPVN P Sbjct: 300 NPDNYFSDVEQAAFSPANIVPGISFSPDKMLQGRLFSYGDAHRYRLGVNHHQIPVNAPKC 359 Query: 378 SKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGPAIPYHWATS 437 F+ RDG M V+GN G+ TY N S Q+ ++ G A HW Sbjct: 360 P--FHNYHRDGAMRVDGNSGNGITYEPN--SGGVFQEQPDFKEPPLSIEGAAD--HWNHR 413 Query: 438 PGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFARVDKGLSEAI 497 + F Q R LY +L + + + I + A + QQR D+F +V + Sbjct: 414 EDEDYFSQPRALYELLSDD--EHQRMFARIAGELSQASKETQQRQIDLFTKVHPEYGAGV 471 Query: 498 K---KVAEAKHA 506 + KV E K A Sbjct: 472 EKAIKVLEGKDA 483 >2ISA-A nrPDB Length = 483 Score = 695 bits (1793), Expect = 0.0, Method: Composition-based stats. Identities = 211/482 (43%), Positives = 285/482 (59%), Gaps = 10/482 (2%) Query: 20 RVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAFGY 79 + +T + G P+ Q G+ GP LLQD ++ LAHF+RE IP+R HA GSGA+G Sbjct: 3 KKLTTAAGCPVAHNQNVQTAGKRGPQLLQDVWFLEKLAHFDREVIPERRMHAKGSGAYGT 62 Query: 80 FEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNLD 139 F VT DIT + +FS IGK+T RFSTV G++G+AD RD RGF+ KFYTEEGN D Sbjct: 63 FTVTHDITKYTKAKIFSDIGKKTDMFARFSTVAGERGAADAERDIRGFSLKFYTEEGNWD 122 Query: 140 WVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVMILFSD 199 NNTPVFF+RDP KFP H KR+P+TN+R A WDF T+ A+HQV I+ SD Sbjct: 123 LAGNNTPVFFLRDPLKFPDLNHAVKRDPRTNMRSAKNNWDFWTS--LPEALHQVTIVMSD 180 Query: 200 RGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDYCQ 259 RG PA YR MHG+ HT+ + N + + ++V+ H + QGIKNL+ EA ++ G++ + Q Sbjct: 181 RGIPATYRHMHGFGSHTFSFINSDNERYWVKFHFVSQQGIKNLSDAEAGELVGNDRESHQ 240 Query: 260 QDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNENP 319 +DL ++I N ++P WT+ +Q M E DA +P++ FDLTKVWP +PL VG+ LN NP Sbjct: 241 RDLLDSIDNQDFPKWTLKVQIMPEADAATVPYNPFDLTKVWPHKDYPLIEVGEFELNRNP 300 Query: 320 LNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNCPYASK 379 N+FA+VEQAAF P+ VP S D +LQ RLF+Y DA RYRLG N IPVN P Sbjct: 301 QNYFAEVEQAAFNPANVVPGISFSPDKMLQGRLFAYGDAQRYRLGVNHQHIPVNAPRCP- 359 Query: 380 FFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGPAIPYHWATSPG 439 + RDG M V+GNFGS Y ND+ + + +G A HW Sbjct: 360 -VHSYHRDGAMRVDGNFGSTLGYEPNDQGQWA--EQPDFSEPPLNLDGAAA--HWDHRED 414 Query: 440 DVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFARVDKGLSEAIKK 499 + F Q +L+ ++ + +Q L N ++ G +IQ R + D E I K Sbjct: 415 EDYFSQPGDLFGLMTAE--KQAILFDNTARNLNGVPKEIQLRHVTHCYKADPAYGEGIGK 472 Query: 500 VA 501 + Sbjct: 473 LL 474 >2XQ1-A nrPDB Length = 509 Score = 691 bits (1783), Expect = 0.0, Method: Composition-based stats. Identities = 290/508 (57%), Positives = 360/508 (70%), Gaps = 19/508 (3%) Query: 21 VVTNSTGNPINEPFVTQR----------IGEHGPLLLQDYNLIDSLAHFNRENIPQRNPH 70 V T S G P+++PF TQR GPLLLQD+ LID+L+HF+RE IP+R H Sbjct: 8 VFTTSQGCPVSDPFTTQRIPLDSTGYKYAPPIGPLLLQDFKLIDTLSHFDRERIPERVVH 67 Query: 71 AHGSGAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATK 130 A G+GA+G FEVTDDITD+C + +GK+T+ TRFSTVGG+KGSADT RDPRGFATK Sbjct: 68 AKGAGAYGVFEVTDDITDVCSAKFLDTVGKKTRIFTRFSTVGGEKGSADTARDPRGFATK 127 Query: 131 FYTEEGNLDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAI 190 FYTE+GNLD VYNNTP+FFIRDP KFPHFIHTQKRNP TNL+D +MFWD+LT N ++ Sbjct: 128 FYTEDGNLDLVYNNTPIFFIRDPIKFPHFIHTQKRNPATNLKDPNMFWDYLTA--NDESL 185 Query: 191 HQVMILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKI 250 HQVM LFS+RGTPA+YR+M+GYSGHTYKW N G+W YVQVH +QG+ NL EEA ++ Sbjct: 186 HQVMYLFSNRGTPASYRTMNGYSGHTYKWYNSKGEWVYVQVHFIANQGVHNLLDEEAGRL 245 Query: 251 AGSNPDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRV 310 AG +PD+ +DL+EAI+ G+YPSW YIQTMT +KKLPFSVFDLTKVWP FPLR Sbjct: 246 AGEDPDHSTRDLWEAIEKGDYPSWECYIQTMTLEQSKKLPFSVFDLTKVWPHKDFPLRHF 305 Query: 311 GKIVLNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQI 370 G+ LNENP N++A+ EQ AF+PS TVP E S DPVLQ+RLFSY D HR+RLGPN+HQI Sbjct: 306 GRFTLNENPKNYYAETEQIAFSPSHTVPGMEPSNDPVLQSRLFSYPDTHRHRLGPNYHQI 365 Query: 371 PVNCPYASKFFNPAIRDGPMNVNGNFGSEPTYL-ANDKSYTY-IQQDRPIQQHQEVWNGP 428 PVNCP S FNP RDGPM V+GN G P Y A + Y + + E + G Sbjct: 366 PVNCPLKSGSFNPINRDGPMCVDGNLGGTPNYANAYNCPIQYAVSPKASGNKPDEKYTGE 425 Query: 429 AIPYHWATSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFAR 488 +PYHW + D D+ Q + ++VLG+ PG+Q++L N+ HV A IQ RVY+ F++ Sbjct: 426 VVPYHWEHT--DYDYFQPKMFWKVLGRTPGEQESLVKNVANHVSAADEFIQDRVYEYFSK 483 Query: 489 VDKGLSEAI-KKVAEAKHASELSSNSKF 515 + + + I KKV E K + SS SK Sbjct: 484 AEPIIGDLIRKKVQELKRKA--SSPSKI 509 >4E37-A nrPDB Length = 484 Score = 683 bits (1762), Expect = 0.0, Method: Composition-based stats. Identities = 210/488 (43%), Positives = 287/488 (58%), Gaps = 11/488 (2%) Query: 18 EDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAF 77 E +T + G P+ + Q G GP+LLQD ++ LAHF+RE IP+R HA GS A+ Sbjct: 1 EKTRLTTAAGAPVVDNQNVQTAGPRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSAAY 60 Query: 78 GYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGN 137 G F VT DIT + +FS++GK+T RFSTV G++G+AD RD RGF+ +FYTE+GN Sbjct: 61 GTFTVTHDITPYTRAKIFSQVGKKTDMFLRFSTVAGERGAADAERDIRGFSMRFYTEQGN 120 Query: 138 LDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVMILF 197 D V NNTPVF++RDP KFP H KR+P+TNLR+A WDF + ++HQ+ I F Sbjct: 121 WDLVGNNTPVFYLRDPLKFPDLNHVVKRDPRTNLRNATFKWDFFSH--LPESLHQLTIDF 178 Query: 198 SDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDY 257 SDRG P +YR +HG+ HT+ + N N + +V+ H KT QGI+NLT EA ++ + + Sbjct: 179 SDRGLPKSYRHIHGFGSHTFSFINANNERFWVKFHFKTQQGIENLTNAEAAEVIAQDRES 238 Query: 258 CQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNE 317 Q+DL+E+I+ G++P W +Y+Q M E++A ++ FDLTKVWP G +PL VG LN Sbjct: 239 SQRDLYESIEKGDFPRWKMYVQIMPEKEAATYRYNPFDLTKVWPHGDYPLIEVGFFELNR 298 Query: 318 NPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNCPYA 377 NP N+FA+VEQAAF P+ VP S D +LQ RLFSY DAHRYRLG N HQIPVN Sbjct: 299 NPDNYFAEVEQAAFTPANVVPGIGFSPDKMLQGRLFSYGDAHRYRLGVNHHQIPVNAARC 358 Query: 378 SKFFNPAIRDGPMNVNGNFGSEP-TYLANDKSYTYIQQDRPIQQHQEVWNGPAIPYHWAT 436 RDG M V+GN + TY N S+ Q+ + G A HW Sbjct: 359 PHQV--YHRDGGMRVDGNNAHQRVTYEPN--SFNQWQEQPDFSEPPLSLEGAAD--HWNH 412 Query: 437 SPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFARVDKGLSEA 496 D + Q L+ + + Q++ L NI + QIQ+R +F +VD + Sbjct: 413 RVDDDYYSQPAALFHLFTDE--QKQRLFANIAEDIRDVPEQIQRRQIGLFLKVDPAYGKG 470 Query: 497 IKKVAEAK 504 + K Sbjct: 471 VADALGLK 478 >3TTT-A nrPDB Length = 753 Score = 674 bits (1740), Expect = 0.0, Method: Composition-based stats. Identities = 192/505 (38%), Positives = 275/505 (54%), Gaps = 24/505 (4%) Query: 12 NYSDVR---EDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRN 68 + DVR E+ +T + G I + + R G GP LL+D+ L + + HF+ E IP+R Sbjct: 67 SLEDVRKGSENYALTTNQGVRIADDQNSLRAGSRGPTLLEDFILREKITHFDHERIPERI 126 Query: 69 PHAHGSGAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFA 128 HA GS A GYF+ ++DI + S K T RFSTV G GSADTVRD RGFA Sbjct: 127 VHARGSAAHGYFQPYKSLSDITKADFLSDPNKITPVFVRFSTVQGGAGSADTVRDIRGFA 186 Query: 129 TKFYTEEGNLDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDA----DMFWDFLTTP 184 TKFYTEEG D V NNTP+FFI+D KFP F+H K P + D FWD+++ Sbjct: 187 TKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFVHAVKPEPHWAIPQGQSAHDTFWDYVSL- 245 Query: 185 ENQVAIHQVMILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTI 244 +H VM SDRG P +YR+M G+ HT++ N G +V+ H K G +L Sbjct: 246 -QPETLHNVMWAMSDRGIPRSYRTMEGFGIHTFRLINAEGKATFVRFHWKPLAGKASLVW 304 Query: 245 EEATKIAGSNPDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQ 304 +EA K+ G +PD+ +++L+EAI+ G++P + + Q + E D K F + D TK+ P+ Sbjct: 305 DEAQKLTGRDPDFHRRELWEAIEAGDFPEYELGFQLIPEEDEFKFDFDLLDPTKLIPEEL 364 Query: 305 FPLRRVGKIVLNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRL- 363 P++RVGK+VLN NP NFFA+ EQAAF P VP + + DP+LQ RL+SY D RL Sbjct: 365 VPVQRVGKMVLNRNPDNFFAENEQAAFHPGHIVPGLDFTNDPLLQGRLYSYTDTQISRLG 424 Query: 364 GPNFHQIPVNCPYASKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRP------ 417 GPNFH+IP+N P RDG M+ G + Y N + + ++ P Sbjct: 425 GPNFHEIPINRPTCPYH--NFQRDG-MHRMGIDTNPANYEPNSINDNWPRETPPGPKRGG 481 Query: 418 IQQHQEVWNGPAIPYHWATSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEG-ACP 476 + +QE G + SP ++ L+ L + P +Q+++ + P Sbjct: 482 FESYQERVEGNKVRE---RSPSFGEYYSHPRLF-WLSQTPFEQRHIVDGFSFELSKVVRP 537 Query: 477 QIQQRVYDMFARVDKGLSEAIKKVA 501 I++RV D A +D L++A+ K Sbjct: 538 YIRERVVDQLAHIDLTLAQAVAKNL 562 >2IQF-A nrPDB Length = 505 Score = 673 bits (1737), Expect = 0.0, Method: Composition-based stats. Identities = 219/496 (44%), Positives = 292/496 (58%), Gaps = 14/496 (2%) Query: 16 VREDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSG 75 V +D T + G P+ + G GP+LLQ ++ LA F+RE IP+R HA GSG Sbjct: 2 VNKDVKQTTAFGAPVWDDNNVITAGPRGPVLLQSTWFLEKLAAFDRERIPERVVHAKGSG 61 Query: 76 AFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEE 135 A+G F VT DIT + +FSK+GK+T+C RFSTV G++GSAD VRDPRGFA K+YTEE Sbjct: 62 AYGTFTVTKDITKYTKAKIFSKVGKKTECFFRFSTVAGERGSADAVRDPRGFAMKYYTEE 121 Query: 136 GNLDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVMI 195 GN D V NNTPVFFIRD KFP FIHTQKR+PQTNL + DM WDF + +++QV Sbjct: 122 GNWDLVGNNTPVFFIRDAIKFPDFIHTQKRDPQTNLPNHDMVWDFWSN--VPESLYQVTW 179 Query: 196 LFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNP 255 + SDRG P ++R M G+ HT+ N G+ +V+ H T QG+K+LT EEA +I +P Sbjct: 180 VMSDRGIPKSFRHMDGFGSHTFSLINAKGERFWVKFHFHTMQGVKHLTNEEAAEIRKHDP 239 Query: 256 DYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVL 315 D Q+DLF+AI G+YP W + IQ M E DAKK F FD+TK+W +PL VG + L Sbjct: 240 DSNQRDLFDAIARGDYPKWKLSIQVMPEEDAKKYRFHPFDVTKIWYTQDYPLMEVGIVEL 299 Query: 316 NENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNCP 375 N+NP N+FA+VEQAAF P+ VP S D +LQ RLFSY D HRYRLG N+ QIPVN P Sbjct: 300 NKNPENYFAEVEQAAFTPANVVPGIGYSPDRMLQGRLFSYGDTHRYRLGVNYPQIPVNKP 359 Query: 376 YASKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQ---EVWNGPAIPY 432 F+ + RDG M NG +GS Y + S ++D+ + + + Sbjct: 360 RCP--FHSSSRDGYMQ-NGYYGSLQNYTPS--SLPGYKEDKSARDPKFNLAHIEKEFEVW 414 Query: 433 HWATSPGD-VDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGAC-PQIQQRVYDMFARVD 490 +W D + Q + YR L +++ L IG + +I + + F + D Sbjct: 415 NWDYRADDSDYYTQPGDYYRSLPAD--EKERLHDTIGESLAHVTHKEIVDKQLEHFKKAD 472 Query: 491 KGLSEAIKKVAEAKHA 506 +E +KK E Sbjct: 473 PKYAEGVKKALEKHQK 488 >1SI8-A nrPDB Length = 484 Score = 663 bits (1711), Expect = 0.0, Method: Composition-based stats. Identities = 208/488 (42%), Positives = 296/488 (60%), Gaps = 13/488 (2%) Query: 18 EDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAF 77 +++ +T S G+P+ + + GE GP+L+QD +L++ LAHFNRE +P+R HA G+GA Sbjct: 2 KNQHLTTSQGSPVGDNQNSLTAGEFGPVLIQDVHLLEKLAHFNRERVPERVVHAKGAGAH 61 Query: 78 GYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGN 137 G F+V+ + + S++GK T RFSTV G+ GS+DT+RDPRGFA KFYT+EGN Sbjct: 62 GIFKVSQSMAQYTKADFLSEVGKETPLFARFSTVAGELGSSDTLRDPRGFALKFYTDEGN 121 Query: 138 LDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVMILF 197 D V NNTP+FFIRD KFP FIH+QKRNP+T+L+ + WDF + + ++HQV IL Sbjct: 122 YDLVGNNTPIFFIRDAIKFPDFIHSQKRNPRTHLKSPEAVWDFWSH--SPESLHQVTILM 179 Query: 198 SDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDY 257 SDRG P ++R MHG+ HT+KW N G+ +V+ H KT+QGIKNL + A +IAG NPD+ Sbjct: 180 SDRGIPLSFRHMHGFGSHTFKWVNAAGEVFFVKYHFKTNQGIKNLESQLAEEIAGKNPDF 239 Query: 258 CQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNE 317 +DL AI+N +PSWT+ +Q + DA + ++FD+TK Q ++PL VG + LN Sbjct: 240 HIEDLHNAIENQEFPSWTLSVQIIPYADALTMKETLFDVTKTVSQKEYPLIEVGTMTLNR 299 Query: 318 NPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNCPYA 377 NP N+FA+VEQ F+P VP EAS D +LQ RLF+Y DAHR+R+G N HQ+P+N A Sbjct: 300 NPENYFAEVEQVTFSPGNFVPGIEASPDKLLQGRLFAYGDAHRHRVGANSHQLPINQAKA 359 Query: 378 SKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGPAIPYHWATS 437 N +DG M N N SE Y N + T ++D + G Y + Sbjct: 360 P--VNNYQKDGNMRFN-NGNSEINYEPNSYTET-PKEDPTAKISSFEVEGNVGNYSYNQ- 414 Query: 438 PGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGA-CPQIQQRVYDMFARVDKGLSEA 496 F QA LY +L + +++NL NI + +I R D+F RV+ Sbjct: 415 ---DHFTQANALYNLLPSE--EKENLINNIAASLGQVKNQEIIARQIDLFTRVNPEYGAR 469 Query: 497 IKKVAEAK 504 + + + + Sbjct: 470 VAQAIKQQ 477 >4QOP-A nrPDB Length = 491 Score = 661 bits (1706), Expect = 0.0, Method: Composition-based stats. Identities = 199/497 (40%), Positives = 285/497 (57%), Gaps = 10/497 (2%) Query: 18 EDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAF 77 + +T + G P+ + ++ G GP L DY+LI+ LAHF+RE IP+R HA G+GA+ Sbjct: 5 NHKNLTTNQGVPVGDNQNSRTAGHRGPSFLDDYHLIEKLAHFDRERIPERVVHARGAGAY 64 Query: 78 GYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGN 137 G FEV + + +A S+ GK+T RFSTV KGS +T+RDPRGFA KFYTEEGN Sbjct: 65 GVFEVENSMEKHTRAAFLSEEGKQTDVFVRFSTVIHPKGSPETLRDPRGFAVKFYTEEGN 124 Query: 138 LDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVMILF 197 D V NN P+FFIRD KFP +H+ K +P TN++D D +WDF+T + H + LF Sbjct: 125 YDLVGNNLPIFFIRDALKFPDMVHSLKPDPVTNIQDPDRYWDFMTL--TPESTHMLTWLF 182 Query: 198 SDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDY 257 SD G PANY M G HT++W NK G+ YV+ H + +GI+NL++EEA +I ++ + Sbjct: 183 SDEGIPANYAEMRGSGVHTFRWVNKYGETKYVKYHWRPSEGIRNLSMEEAAEIQANDFQH 242 Query: 258 CQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNE 317 +DL++ I+ GNYP+W +Y+Q M D +L + D TK W + +PL++VG++ LN Sbjct: 243 ATRDLYDRIEKGNYPAWDLYVQLMPLSDYDELDYDPCDPTKTWSEEDYPLQKVGRMTLNR 302 Query: 318 NPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNCPYA 377 NP NFFA+ EQAAF PS VP EAS D +LQ RLFSY D R+RLG N+ +IPVNCPYA Sbjct: 303 NPENFFAETEQAAFTPSALVPGIEASEDKLLQGRLFSYPDTQRHRLGANYMRIPVNCPYA 362 Query: 378 SKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGPAIPYHWATS 437 N +DG M G Y N +++ ++ + V +G + Sbjct: 363 PVHNN--QQDGFMTTTRPSGH-INYEPNRYDDQ-PKENPHYKESEPVLHGDRMVRQKIEK 418 Query: 438 PGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFARVDKGLSEAI 497 P D F QA YR ++ +++ L N+ ++G + + F R D+ + + Sbjct: 419 PND--FKQAGEKYRSYSEE--EKQALIKNLTADLKGVNEKTKLLAICNFYRADEDYGQRL 474 Query: 498 KKVAEAKHASELSSNSK 514 S L + K Sbjct: 475 ADSLGVDIRSYLQGSMK 491 >4B7G-A nrPDB Length = 515 Score = 634 bits (1636), Expect = 0.0, Method: Composition-based stats. Identities = 208/499 (41%), Positives = 278/499 (55%), Gaps = 21/499 (4%) Query: 23 TNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAFGYFEV 82 T G P+ ++ G GP +L D +LI+ LAHFNREN+P+R PHA G GAFG + Sbjct: 23 TRHNGAPVPSENISATAGPQGPNVLNDIHLIEKLAHFNRENVPERIPHAKGHGAFGELHI 82 Query: 83 TDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNLDWVY 142 T+D+++ + +F + GK T RFSTV G++GS DT RD GFA +FYTEEGN D V Sbjct: 83 TEDVSEYTKADLF-QPGKVTPLAVRFSTVAGEQGSPDTWRDVHGFALRFYTEEGNYDIVG 141 Query: 143 NNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVMILFSDRGT 202 NNTP FF+RD KFP FIH+QKR + LRDADM WDF T + HQV L DRGT Sbjct: 142 NNTPTFFLRDGMKFPDFIHSQKRLNKNGLRDADMQWDFWT--RAPESAHQVTYLMGDRGT 199 Query: 203 PANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDYCQQDL 262 P R G+ HT++W N G +V+ H KT QG T EA K+AG N DY ++DL Sbjct: 200 PKTSRHQDGFGSHTFQWINAEGKPVWVKYHFKTRQGWDCFTDAEAAKVAGENADYQREDL 259 Query: 263 FEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNENPLNF 322 + AI+NG++P W V +Q M DA+ ++ FDLTK W Q +PL VG +LN NP NF Sbjct: 260 YNAIENGDFPIWDVKVQIMPFEDAENYRWNPFDLTKTWSQKDYPLIPVGYFILNRNPRNF 319 Query: 323 FAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNCPYASKFFN 382 FAQ+EQ A P VP S D +LQAR+F+YAD RYR+G N+ +PVN P N Sbjct: 320 FAQIEQIALDPGNIVPGVGLSPDRMLQARIFAYADQQRYRIGANYRDLPVNRPINE--VN 377 Query: 383 PAIRDGPMNVNGNFGSEPTYLAN--DKSYTYIQQDRPIQQHQEVW-------------NG 427 R+G M + EP+Y N DK Y+ + + Sbjct: 378 TYSREGSMQYIFDAEGEPSYSPNRYDKGAGYLDNGTDSSSNHTSYGQADDIYVNPDPHGT 437 Query: 428 PAIPYHWATSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFA 487 + + D DF+Q LYR + + G+++ LA NI ++G + RVYD + Sbjct: 438 DLVRAAYVKHQDDDDFIQPGILYREVLDE-GEKERLADNISNAMQGISEATEPRVYDYWN 496 Query: 488 RVDKGLSEAIKKVAEAKHA 506 VD+ L +K++ K A Sbjct: 497 NVDENLGARVKELYLQKKA 515 >4CAB-A nrPDB Length = 536 Score = 631 bits (1627), Expect = 0.0, Method: Composition-based stats. Identities = 178/499 (35%), Positives = 265/499 (53%), Gaps = 19/499 (3%) Query: 18 EDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAF 77 + +T G+P+++ ++ +G GP+ L++Y I+ L+HF+RE IP+R HA G GA Sbjct: 29 QGTTLTTRQGHPVHDNQNSRTVGSRGPMTLENYQFIEKLSHFDRERIPERVVHARGVGAH 88 Query: 78 GYFEVTDDI-----TDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFY 132 G F T + + + +F + GK T RFSTVG S +T+RDPRGFA KFY Sbjct: 89 GVFRATGKVGDEPVSKYTRAKLFQEDGKETPVFVRFSTVGHGTHSPETLRDPRGFAVKFY 148 Query: 133 TEEGNLDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQ 192 TE+GN D V NN +FFIRD KFP IH+QK +P TN++ + +DF + A H Sbjct: 149 TEDGNWDLVGNNLKIFFIRDALKFPDLIHSQKPSPTTNIQSQERIFDFFAG--SPEATHM 206 Query: 193 VMILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAG 252 + +L+S G PA+YR M G +TYKW N G+ V+ H + QG++NLT +A ++ Sbjct: 207 ITLLYSPWGIPASYRFMQGSGVNTYKWVNDQGEGVLVKYHWEPVQGVRNLTQMQADEVQA 266 Query: 253 SNPDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGK 312 +N ++ QDL +AI+ G++P W +++Q M + + +L F D TK+WP+ QFP R VG+ Sbjct: 267 TNFNHATQDLHDAIERGDFPQWDLFVQIMEDGEHPELDFDPLDDTKIWPREQFPWRHVGQ 326 Query: 313 IVLNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPV 372 + LN NP N FA+ EQAAF V + S D +LQ R FSY+D RYR+GPN+ Q+P+ Sbjct: 327 MTLNRNPENVFAETEQAAFGTGVLVDGLDFSDDKMLQGRTFSYSDTQRYRVGPNYLQLPI 386 Query: 373 NCPYASKFFNPAIRDGPMNVNGN----FGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGP 428 N P K RDG M + Y + S R +H G Sbjct: 387 NAPK--KHVATNQRDGQMAYRVDTFEGQDQRVNYEPSLLSGPKEAP-RRAPEHTPRVEGN 443 Query: 429 AIPYHWATSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFAR 488 + F QA YR ++ L N+ + G +IQ ++ + F Sbjct: 444 LVRAAIER---PNPFGQAGMQYRNFADW--ERDELVSNLSGALAGVDKRIQDKMLEYFTA 498 Query: 489 VDKGLSEAIKKVAEAKHAS 507 D + +++ +AK A Sbjct: 499 ADADYGQRVREGIQAKEAE 517 >4BIM-A nrPDB Length = 746 Score = 623 bits (1606), Expect = e-179, Method: Composition-based stats. Identities = 173/511 (33%), Positives = 258/511 (50%), Gaps = 30/511 (5%) Query: 6 QEKNEVNYSDVREDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIP 65 Q EV D + +T G I E F + + G G LL+D+ L HF+ E IP Sbjct: 68 QRLKEVEVDD--NGQFMTTDFGGNIEEQF-SLKAGGRGSTLLEDFIFRQKLQHFDHERIP 124 Query: 66 QRNPHAHGSGAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPR 125 +R HA G+GA G F D ++I ++ K+T RFSTV G +GSADT RD Sbjct: 125 ERVVHARGAGAHGIFTSYGDWSNITAASFLGAKDKQTPVFVRFSTVAGSRGSADTARDVH 184 Query: 126 GFATKFYTEEGNLDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDA----DMFWDFL 181 GFAT+FYT+EGN D V NN PVFFI+D +FP IH+ K +P + A D WDF Sbjct: 185 GFATRFYTDEGNFDIVGNNIPVFFIQDAIRFPDLIHSVKPSPDNEVPQAATAHDSAWDFF 244 Query: 182 TTPENQVAIHQVMILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKN 241 ++ A+H + S G P +YR M G+ HT++ ++G V+ H KT QG Sbjct: 245 SS--QPSALHTLFWAMSGNGIPRSYRHMDGFGIHTFRLVTEDGKSKLVKWHWKTKQGKAA 302 Query: 242 LTIEEATKIAGSNPDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWP 301 L EEA +AG N D+ +QDL++AI++GN PSW + +Q + E A+ F + D TK P Sbjct: 303 LVWEEAQVLAGKNADFHRQDLWDAIESGNAPSWELAVQLIDEDKAQAYGFDLLDPTKFLP 362 Query: 302 QGQFPLRRVGKIVLNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRY 361 + PL+ +G++ LN NP+N+FA+ EQ +F P V + + DP+LQ RL+SY D Sbjct: 363 EEFAPLQVLGEMTLNRNPMNYFAETEQISFQPGHIVRGVDFTEDPLLQGRLYSYLDTQLN 422 Query: 362 RL-GPNFHQIPVNCPYASKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQ 420 R GPNF Q+P+N P + N G ++ N + S +Y+ + P Q Sbjct: 423 RHRGPNFEQLPINRPVSGVHNNHRDGQGQAWIHKNI--------HHYSPSYLNKGYPAQA 474 Query: 421 HQEVWNG--------PAIPYHWATSPG-DVDFVQARNLYRVLGKQPGQQKNLAYNIGIHV 471 +Q V G + + S D + Q R + L P +Q+ + I Sbjct: 475 NQTVGRGFFTTPGRTASGVLNRELSATFDDHYTQPRLFFNSL--TPVEQQFVINAIRFEA 532 Query: 472 EGA-CPQIQQRVYDMFARVDKGLSEAIKKVA 501 Q+++ V + ++ +++ + Sbjct: 533 SHVTNEQVKKNVLEQLNKISNDVAKRVAVAL 563 >1GWF-A nrPDB Length = 503 Score = 623 bits (1606), Expect = e-179, Method: Composition-based stats. Identities = 202/485 (41%), Positives = 280/485 (57%), Gaps = 10/485 (2%) Query: 23 TNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAFGYFEV 82 T G P + +G GP++L D +L+++ HFNR NIP+R PHA GSGAFG FEV Sbjct: 14 TRQNGAPAVSDRQSLTVGSEGPIVLHDTHLLETHQHFNRMNIPERRPHAKGSGAFGEFEV 73 Query: 83 TDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNLDWVY 142 T+D++ + +F + G +T+ L RFSTV G+ GS DT RD RGFA +FYTEEGN D V Sbjct: 74 TEDVSKYTKALVF-QPGTKTETLLRFSTVAGELGSPDTWRDVRGFALRFYTEEGNYDLVG 132 Query: 143 NNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVMILFSDRGT 202 NNTP+FF+RDP KF HFI +QKR P + LRDA M WDF T N + HQV L RG Sbjct: 133 NNTPIFFLRDPMKFTHFIRSQKRLPDSGLRDATMQWDFWTN--NPESAHQVTYLMGPRGL 190 Query: 203 PANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDYCQQDL 262 P +R M+GY HTY W N G+ H+V+ H + QG+ NL+ +EATKIAG N D+ +QDL Sbjct: 191 PRTWREMNGYGSHTYLWVNAQGEKHWVKYHFISQQGVHNLSNDEATKIAGENADFHRQDL 250 Query: 263 FEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNENPLNF 322 FE+I G++P W +YIQ + + K F+ FDLTK Q +P +VG + LN NP N Sbjct: 251 FESIAKGDHPKWDLYIQAIPYEEGKTYRFNPFDLTKTISQKDYPRIKVGTLTLNRNPENH 310 Query: 323 FAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNCPYASKFFN 382 FAQ+E AAF+PS TVP S D +L R F+Y DA YR+G + +Q+PVN P + + Sbjct: 311 FAQIESAAFSPSNTVPGIGLSPDRMLLGRAFAYHDAQLYRVGAHVNQLPVNRPKNA--VH 368 Query: 383 PAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGPAIPYHWATSPGDVD 442 +G M + + G TY+ N ++ + P+ E +G A D D Sbjct: 369 NYAFEGQMWYD-HTGDRSTYVPNSNGDSWSDETGPVDDGWEA-DGTLTREAQALRADDDD 426 Query: 443 FVQARNLYR-VLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFARVDKGLSEAIKKVA 501 F QA L R V Q ++ + + ++G +Q R ++ + VD + + I+ Sbjct: 427 FGQAGTLVREVFSDQ--ERDDFVETVAGALKGVRQDVQARAFEYWKNVDATIGQRIEDEV 484 Query: 502 EAKHA 506 + Sbjct: 485 KRHEG 489 >2J2M-A nrPDB Length = 491 Score = 620 bits (1598), Expect = e-178, Method: Composition-based stats. Identities = 172/487 (35%), Positives = 263/487 (54%), Gaps = 11/487 (2%) Query: 18 EDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAF 77 ++ +T + G PI + ++ G GP LL+DY LI+ +AHF+RE +P+R HA G GA Sbjct: 4 NEKKLTTNQGVPIGDNQNSRTAGRRGPTLLEDYQLIEKIAHFDRERVPERVVHARGFGAH 63 Query: 78 GYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGN 137 G F+V + + +A + G RFSTV S +T+RDPRGF+ KFYTEEGN Sbjct: 64 GVFKVKNSMKKYTKAAFLQEEGTEVPVFARFSTVIHGTHSPETLRDPRGFSVKFYTEEGN 123 Query: 138 LDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVMILF 197 D+V NN PVFFIRD KFP +H+ K +P+TN++D D +WDF+T + + +M +F Sbjct: 124 WDFVGNNLPVFFIRDAMKFPDMVHSLKPDPRTNIQDPDRYWDFMTL--RPESTNMLMHIF 181 Query: 198 SDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDY 257 +D G PA+YR M G S H++KW N +G+ Y+++ +G+ NL+ +EAT++ G + ++ Sbjct: 182 TDEGIPASYRKMRGSSVHSFKWVNAHGNTVYIKLRWVPKEGVHNLSADEATEVQGKDFNH 241 Query: 258 CQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNE 317 D F+AI+NG++P W +++Q + D + F D TK W + P + VG + LN+ Sbjct: 242 ASNDTFQAIENGDFPEWDLFVQVLDPADVENFDFDPLDATKDWFEDVIPFQHVGTMTLNK 301 Query: 318 NPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNCPYA 377 N N+FA+ E F P VP S D +LQ RLFSY+D R+R+GPN+ Q+P+NCP+A Sbjct: 302 NVDNYFAETESVGFNPGVLVPGMLPSEDKLLQGRLFSYSDTQRHRIGPNYQQLPINCPFA 361 Query: 378 SKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGPAIPYHWATS 437 N RDG M S Y N +Q + + + + Sbjct: 362 Q--VNNYQRDGAMPF-KQQTSSVNYEPNRYQD-EPKQTPEYTEDTQPLHDDI--HGRLEI 415 Query: 438 PGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGAC-PQIQQRVYDMFARVDKGLSEA 496 +F QA +YR + ++ +Q L N+ ++ F R D L E Sbjct: 416 EKTNNFGQAGEVYRRMTEE--EQMALLNNLVNDLQQVRHENTVLLAICNFYRADASLGEK 473 Query: 497 IKKVAEA 503 + + Sbjct: 474 LSEALNV 480 >4B7A-A nrPDB Length = 719 Score = 604 bits (1558), Expect = e-173, Method: Composition-based stats. Identities = 163/493 (33%), Positives = 248/493 (50%), Gaps = 22/493 (4%) Query: 21 VVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAFGYF 80 +T+ G PI + + + G GP LL+D+ + HF+ E +P+R HA G+GA G F Sbjct: 55 YLTSDVGGPIQD-QTSLKAGIRGPTLLEDFMFRQKIQHFDHERVPERAVHARGAGAHGTF 113 Query: 81 EVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNLDW 140 D ++I ++ + GK+T RFSTV G +GSADT RD GFAT+FYT+EGN D Sbjct: 114 TSYADWSNITAASFLNATGKQTPVFVRFSTVAGSRGSADTARDVHGFATRFYTDEGNFDI 173 Query: 141 VYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDA----DMFWDFLTTPENQVAIHQVMIL 196 V NN PVFFI+D +FP IH+ K P + A D WDF + + +H + Sbjct: 174 VGNNIPVFFIQDAIQFPDLIHSVKPRPDNEIPQAATAHDSAWDFFS--QQPSTMHTLFWA 231 Query: 197 FSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPD 256 S G P +YR M G+ HT+++ +G ++ H K+ QG +L EEA ++G N D Sbjct: 232 MSGHGIPRSYRHMDGFGVHTFRFVKDDGSSKLIKWHFKSRQGKASLVWEEAQVLSGKNAD 291 Query: 257 YCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLN 316 + +QDL++AI++GN P W V +Q + E A+ F + D TK+ P+ PL ++G + L+ Sbjct: 292 FHRQDLWDAIESGNGPEWDVCVQIVDESQAQAFGFDLLDPTKIIPEEYAPLTKLGLLKLD 351 Query: 317 ENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYR-LGPNFHQIPVNCP 375 NP N+FA+ EQ F P V + + DP+LQ RLFSY D R GPNF Q+P+N P Sbjct: 352 RNPTNYFAETEQVMFQPGHIVRGIDFTEDPLLQGRLFSYLDTQLNRNGGPNFEQLPINMP 411 Query: 376 YASKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRP------IQQHQEVWNGPA 429 N G M ++ N + Y N + Y +Q +G Sbjct: 412 RVPIHNNNRDGAGQMFIHRN---KYPYTPNTLNSGYPRQANQNAGRGFFTAPGRTASGAL 468 Query: 430 IPYHWATSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGA-CPQIQQRVYDMFAR 488 + T + + Q R + L P +Q+ L + + ++++ V R Sbjct: 469 VREVSPTF--NDHWSQPRLFFNSL--TPVEQQFLVNAMRFEISLVKSEEVKKNVLTQLNR 524 Query: 489 VDKGLSEAIKKVA 501 V ++ + Sbjct: 525 VSHDVAVRVAAAI 537 >1SY7-A nrPDB Length = 715 Score = 602 bits (1552), Expect = e-172, Method: Composition-based stats. Identities = 177/519 (34%), Positives = 254/519 (48%), Gaps = 33/519 (6%) Query: 12 NYSDVREDRVVTNSTGNPINEPFVTQRIGEH---GPLLLQDYNLIDSLAHFNRENIPQRN 68 + + + +T G RI GP LL+D + + F+ E IP+R Sbjct: 10 EFKETDKSARLTTDYGVKQTTADDWLRIVSDDKIGPSLLEDPFARERIMRFDHERIPERV 69 Query: 69 PHAHGSGAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFA 128 HA GSGAFG F+V + +D+ + + + + T RFSTV G +GSADTVRD RGFA Sbjct: 70 VHARGSGAFGKFKVYESASDLTMAPVLTDTSRETPVFVRFSTVLGSRGSADTVRDVRGFA 129 Query: 129 TKFYTEEGNLDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDA----DMFWDFLTTP 184 KFYTEEGN D V NN PVFFI+D KFP IH K P + A + FWDF Sbjct: 130 VKFYTEEGNWDLVGNNIPVFFIQDAIKFPDVIHAGKPEPHNEVPQAQSAHNNFWDFQFN- 188 Query: 185 ENQVAIHQVMILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTI 244 + A H SDR P + R M G+ +TY N G H+V+ H + G+ +L Sbjct: 189 -HTEATHMFTWAMSDRAIPRSLRMMQGFGVNTYTLINAQGKRHFVKFHWTPELGVHSLVW 247 Query: 245 EEATKIAGSNPDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQ 304 +EA K+AG +PD+ ++DL+EAI+NG YP W IQ + E D K F + D TK+WP+ Sbjct: 248 DEALKLAGQDPDFHRKDLWEAIENGAYPKWKFGIQAIAEEDEHKFDFDILDATKIWPEDL 307 Query: 305 FPLRRVGKIVLNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLG 364 P+R +G++ LN NP FF Q EQ AF S V S DP+LQ R FSY D RLG Sbjct: 308 VPVRYIGEMELNRNPDEFFPQTEQIAFCTSHVVNGIGFSDDPLLQGRNFSYFDTQISRLG 367 Query: 365 PNFHQIPVNCPYASKFFNPAIRDGPMNVNGNFGSEPTYLAN---------DKSYTYIQQD 415 NF ++P+N P RDG M + G+ Y N K Y++ Sbjct: 368 VNFQELPINRPVCPVM--NFNRDGAMRHTISRGTV-NYYPNRFDACPPASLKEGGYLEYA 424 Query: 416 RPIQQHQEVWNGPAIPYHWATSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGA- 474 + + + H F QA+ Y + P +++++ G ++ Sbjct: 425 QKVAGIKARARSAKFKEH---------FSQAQLFYNSMS--PIEKQHMINAFGFELDHCE 473 Query: 475 CPQIQQRVYDMFARVDKGLSEAIKKVAEAKHASELSSNS 513 P + R+ A +D GL++ I ++ + + + + Sbjct: 474 DPVVYGRMVQRLADIDLGLAQTIAEMVGGEAPTTTNHPN 512 >2IUF-A nrPDB Length = 688 Score = 589 bits (1518), Expect = e-168, Method: Composition-based stats. Identities = 163/518 (31%), Positives = 252/518 (48%), Gaps = 24/518 (4%) Query: 6 QEKNEVNYSDVREDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIP 65 Q ++ +D +D +T++ G PI + + G+ G LLQD+ + + F+ E +P Sbjct: 2 QFLSQFYLND--QDVYLTSNVGGPIQDE-NSLSAGQRGATLLQDFIFREKIQRFDHERVP 58 Query: 66 QRNPHAHGSGAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPR 125 +R HA G+GA G F D +++ ++ S GK T TRFSTV G +GSADT RD Sbjct: 59 ERAVHARGTGAHGTFTSYGDWSNLTAASFLSAEGKETPMFTRFSTVAGSRGSADTARDVH 118 Query: 126 GFATKFYTEEGNLDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDA----DMFWDFL 181 GFAT+FYT+EGN D V NN PVFFI+D FP IH K + A D WDF Sbjct: 119 GFATRFYTDEGNFDIVGNNIPVFFIQDAILFPDLIHAVKPRGDNQIPQAATAHDSAWDFF 178 Query: 182 TTPENQVAIHQVMILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKN 241 + + +H ++ + G P ++R ++G+ HT++ +G V+ H K QG + Sbjct: 179 S--QQPSVLHTLLWAMAGHGIPRSFRHVNGFGVHTFRLVTDDGKTKLVKFHWKGLQGKAS 236 Query: 242 LTIEEATKIAGSNPDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWP 301 EEA + AG N D+ +QDLF++IQ G +P W + +Q M E+D K F + D TK+ P Sbjct: 237 FVWEEAQQTAGKNADFMRQDLFQSIQAGRFPEWELGVQIMQEQDQLKFGFDLLDPTKIVP 296 Query: 302 QGQFPLRRVGKIVLNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRY 361 + P+ +GK+ LN NP+N+FA+ EQ F P V + + DP+LQ RLFSY D Sbjct: 297 EELVPVTILGKMQLNRNPMNYFAETEQVMFQPGHIVRGVDFTEDPLLQGRLFSYLDTQLN 356 Query: 362 RL-GPNFHQIPVNCPYASKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRP--- 417 R GPNF Q+P+N P A N G M + + Y N ++ +Q Sbjct: 357 RHGGPNFEQLPINRPRAPIHNNNRDGAGQMFIPLD---PNAYSPNTENKGSPKQANETVG 413 Query: 418 ---IQQHQEVWNGPAIPYHWATSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGA 474 + +G ++ + ++ Q R + L Q++ + + Sbjct: 414 KGFFTAPERTASGKLQR--TLSTTFENNWSQPRLFWNSLVN--AQKEFIVDAMRFETSNV 469 Query: 475 -CPQIQQRVYDMFARVDKGLSEAIKKVAEAKHASELSS 511 ++ V R+ L+ + + SS Sbjct: 470 SSSVVRDDVIIQLNRISDNLATRVASAIGVEAPKPNSS 507 >1M7S-A nrPDB Length = 484 Score = 579 bits (1493), Expect = e-166, Method: Composition-based stats. Identities = 169/483 (34%), Positives = 246/483 (50%), Gaps = 15/483 (3%) Query: 21 VVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAFGYF 80 +T G + + +Q G GP+LLQD L+ L F+RE IP+R HA G+G G F Sbjct: 3 TLTRDNGAVVGDNQNSQTAGAQGPVLLQDVQLLQKLQRFDRERIPERVVHARGTGVKGEF 62 Query: 81 EVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNLDW 140 + DI+D+ + +F K G++T RFS+V S +T+RDP GFATKFYT +GN D Sbjct: 63 TASADISDLSKATVF-KSGEKTPVFVRFSSVVHGNHSPETLRDPHGFATKFYTADGNWDL 121 Query: 141 VYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVMILFSDR 200 V NN P FFIRD KFP +H K +P+TNL + +DF + A + +L+S+ Sbjct: 122 VGNNFPTFFIRDAIKFPDMVHAFKPDPRTNLDNDSRRFDFFSH--VPEATRTLTLLYSNE 179 Query: 201 GTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDYCQQ 260 GTPA YR M G H YK N G+ HYV+ H K+ QGIKNL +E ++ + + Sbjct: 180 GTPAGYRFMDGNGVHAYKLVNAKGEVHYVKFHWKSLQGIKNLDPKEVAQVQSKDYSHLTN 239 Query: 261 DLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIVLNENPL 320 DL AI+ G++P W +Y+Q + + K F D TK+WP P +++G++VLN+N Sbjct: 240 DLVGAIKKGDFPKWDLYVQVLKPEELAKFDFDPLDATKIWP--DVPEKKIGQMVLNKNVD 297 Query: 321 NFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGPNFHQIPVNCPYASKF 380 NFF + EQ A AP+ VP E S D +LQ R+FSYAD YRLG N +PVN P + Sbjct: 298 NFFQETEQVAMAPANLVPGIEPSEDRLLQGRVFSYADTQMYRLGANGLSLPVNQPKVA-- 355 Query: 381 FNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGPAIPYHWATSPGD 440 N +DG +N G+ S Y + + Sbjct: 356 VNNGNQDGALNT-GHTTSGVNYEPSRLEPRPADDKARYSELPLSGTTQQAKITREQ---- 410 Query: 441 VDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEGACPQIQQRVYDMFARVDKGLSEAIKKV 500 +F QA +LYR + ++ +L G + + + + + D + +V Sbjct: 411 -NFKQAGDLYRSYSAK--EKTDLVQKFGESLADTLTESKNIMLSYLYKEDPNYGTRVAEV 467 Query: 501 AEA 503 A+ Sbjct: 468 AKG 470 >1YE9-A nrPDB Length = 226 Score = 355 bits (911), Expect = 2e-98, Method: Composition-based stats. Identities = 98/227 (43%), Positives = 128/227 (56%), Gaps = 6/227 (2%) Query: 18 EDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENIPQRNPHAHGSGAF 77 E+ +T + G I + + R G GP LL+D+ L + + HF+ E IP+R HA GS A Sbjct: 2 ENYALTTNQGVRIADDQNSLRAGSRGPTLLEDFILREKITHFDHERIPERIVHARGSAAH 61 Query: 78 GYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGN 137 GYF+ ++DI + S K T RFSTV G GSADTVRD RGFATKFYTEEG Sbjct: 62 GYFQPYKSLSDITKADFLSDPNKITPVFVRFSTVQGGAGSADTVRDIRGFATKFYTEEGI 121 Query: 138 LDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDA----DMFWDFLTTPENQVAIHQV 193 D V NNTP+FFI+D KFP F+H K P + D FWD+++ +H V Sbjct: 122 FDLVGNNTPIFFIQDAHKFPDFVHAVKPEPHWAIPQGQSAHDTFWDYVSL--QPETLHNV 179 Query: 194 MILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIK 240 M SDRG P +YR+M G+ HT++ N G +V+ H K G Sbjct: 180 MWAMSDRGIPRSYRTMEGFGIHTFRLINAEGKATFVRFHWKPLAGKA 226 >3E4Y-A nrPDB Length = 320 Score = 313 bits (802), Expect = 1e-85, Method: Composition-based stats. Identities = 68/301 (22%), Positives = 110/301 (36%), Gaps = 21/301 (6%) Query: 67 RNPHAHGSGAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRG 126 R HA G+ G F T D + + G L RFS G+ D RG Sbjct: 32 RALHAKGTLYRGTFTATRDAVMLSAAPHLD--GSTVPALIRFSNGSGNPKQRDGAPGVRG 89 Query: 127 FATKFYTEEGNLDWVYNNTPVFFIRD-PSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPE 185 A KF +G+ V T + P F + + T LR + LT P Sbjct: 90 MAVKFTLPDGSTTDVSAQTARLLVSSTPEGFIDLLKAMRPGLTTPLR---LATHLLTHPR 146 Query: 186 NQVAIHQVMILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIE 245 + + +L PA+Y + + H ++W +G +V+ H+ + L+ Sbjct: 147 ---LLGALPLLREANRIPASYATTEYHGLHAFRWIAADGSARFVRYHLVPTAAEEYLSAS 203 Query: 246 EATKIAGSNPDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQF 305 +A G +PD+ +L +Q+G + +Q D S D + W Q Sbjct: 204 DAR---GKDPDFLTDELAARLQDGPV-RFDFRVQIAGPTD------STVDPSSAWQSTQ- 252 Query: 306 PLRRVGKIVLNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLGP 365 + VG + + + F P E S DPVL+ R Y+ + + R G Sbjct: 253 -IVTVGTVTITGPDTEREHGGDIVVFDPMRVTDGIEPSDDPVLRFRTLVYSASVKLRTGV 311 Query: 366 N 366 + Sbjct: 312 D 312 >1YE9-E nrPDB Length = 259 Score = 301 bits (770), Expect = 6e-82, Method: Composition-based stats. Identities = 89/261 (34%), Positives = 138/261 (52%), Gaps = 15/261 (5%) Query: 249 KIAGSNPDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLR 308 K+ G +PD+ +++L+EAI+ G++P + + Q + E D K F + D TK+ P+ P++ Sbjct: 1 KLTGRDPDFHRRELWEAIEAGDFPEYELGFQLIPEEDEFKFDFDLLDPTKLIPEELVPVQ 60 Query: 309 RVGKIVLNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRL-GPNF 367 RVGK+VLN NP NFFA+ EQAAF P VP + + DP+LQ RLFSY D RL GPNF Sbjct: 61 RVGKMVLNRNPDNFFAENEQAAFHPGHIVPGLDFTNDPLLQGRLFSYTDTQISRLGGPNF 120 Query: 368 HQIPVNCPYASKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRP------IQQH 421 H+IP+N P RDG M+ G + Y N + + ++ P + + Sbjct: 121 HEIPINRPTCPYH--NFQRDG-MHRMGIDTNPANYEPNSINDNWPRETPPGPKRGGFESY 177 Query: 422 QEVWNGPAIPYHWATSPGDVDFVQARNLYRVLGKQPGQQKNLAYNIGIHVEG-ACPQIQQ 480 QE G + SP ++ L+ L + P +Q+++ + P I++ Sbjct: 178 QERVEGNKVRE---RSPSFGEYYSHPRLF-WLSQTPFEQRHIVDGFSFELSKVVRPYIRE 233 Query: 481 RVYDMFARVDKGLSEAIKKVA 501 RV D A +D L++A+ K Sbjct: 234 RVVDQLAHIDLTLAQAVAKNL 254 >1U5U-A nrPDB Length = 374 Score = 55.1 bits (131), Expect = 7e-08, Method: Composition-based stats. Identities = 54/291 (18%), Positives = 95/291 (32%), Gaps = 44/291 (15%) Query: 67 RNPHAHGSGAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRG 126 R H G+G G + +D F+ G+ R + + K D D R Sbjct: 64 RATHTVGTGGIGEITIVND-PKFPEHEFFTA-GRTFPARLRHANL---KYPDDAGADARS 118 Query: 127 FATKF--YTEEGNLDWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTP 184 F+ KF +G LD V N + F+ + + D Sbjct: 119 FSIKFADSDSDGPLDIVMNTGEANIFWNSPSLEDFV---------PVEEGDAA----EEY 165 Query: 185 ENQVAIHQVMILFSDRGTPANYRSMHGYSGHTYKWSNKNGDWHYVQVH-------IKTDQ 237 + + ++ + R P + ++ YS T + K+G Y + IK + Sbjct: 166 VYKNPYYYYNLVEALRRAPDTFAHLYYYSQVTMPFKAKDGKVRYCRYRALPGDVDIKEED 225 Query: 238 GIKNLTIEEATKI--------AGSNPDYCQQDLFEAIQNGNYPSWTVYIQT--MTERDAK 287 LT EE KI DY +++ E +Q G ++ + IQ + D Sbjct: 226 ESGRLTEEEQRKIWIFSRHENEKRPDDYLRKEYVERLQKGPV-NYRLQIQIHEASPDDTA 284 Query: 288 KLPFSVFDLTKVWPQGQFPLRRVGKIVLNEN--PLNFFAQVEQAAFAPSTT 336 +F +W + P + K+ + P A P++ Sbjct: 285 T----IFHAGILWDKETHPWFDLAKVSIKTPLSPDVLEKTAFNIANQPASL 331 >5WQK-A nrPDB Length = 293 Score = 34.7 bits (78), Expect = 0.097, Method: Composition-based stats. Identities = 21/106 (19%), Positives = 41/106 (38%), Gaps = 8/106 (7%) Query: 171 LRDADMFWDFLTTPENQVAIHQVMILFSDRGT---PANYRSMHGYSGHTYKWSNKNGDWH 227 L +A F D+ + A H V+ SD+G P + + H+ G H Sbjct: 72 LPNATHFADYAGSLGVSAATHVVIYDGSDQGLYSAPRVWWMFRAFGHHSVSLL-DGGFRH 130 Query: 228 YVQVHIKTDQGIKNLTIEEATKIAGSNPDYCQ--QDLFEAIQNGNY 271 ++ ++ G + E A A +P + + +D+ E + + Sbjct: 131 WLNQNLPISSGKSH--SEPAEFSAQLDPSFIKTHEDILENLDARRF 174 >2W8Z-A nrPDB Length = 470 Score = 33.9 bits (76), Expect = 0.18, Method: Composition-based stats. Identities = 29/128 (22%), Positives = 47/128 (36%), Gaps = 30/128 (23%) Query: 125 RGFA-TKFYTEEGNLDWVYNNTPVFFIRDPSKFPHFIHTQK----RNPQ-TNLRDADMFW 178 +GFA K +EE N + Y + + F F+ K R+P +NL F Sbjct: 337 QGFAQMKAASEEYNWNLRYGDIAMIFRGGCIIRAQFLQKIKEAYDRDPALSNLLLDSYFK 396 Query: 179 DFLTTPENQVAIHQVMILFSDRGTP-----------ANYRSM-----------HGYSGHT 216 D Q A+ +++ + RG P +YR+ + HT Sbjct: 397 DI--VERYQDALREIVATAAMRGIPVPGSASALAYYDSYRTAVLPANLIQAQRDYFGAHT 454 Query: 217 YKWSNKNG 224 Y+ +K G Sbjct: 455 YERVDKEG 462 >4OUA-B nrPDB Length = 557 Score = 32.0 bits (71), Expect = 0.57, Method: Composition-based stats. Identities = 25/157 (15%), Positives = 54/157 (34%), Gaps = 24/157 (15%) Query: 149 FIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVMILFSDRGTPANYRS 208 F+RD F +I + + D F+ IH + F+ P + + Sbjct: 21 FVRDEKFFTLYIRALQAIQDKDQSDYSSFFQL-------SGIHGLP--FTPWAKPKDTPT 71 Query: 209 M---HGYSGHTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDYCQQDLFEA 265 + GY H+ + H + I ++EA K +++ +A Sbjct: 72 VPYESGYCTHS--------QVLFPTWH-RVYVSIYEQILQEAAKGIAKKFTVHKKEWAQA 122 Query: 266 IQNGNYPSWTVYIQTMTERD---AKKLPFSVFDLTKV 299 ++ P W + + +++ + +D TK+ Sbjct: 123 AEDLRQPYWDTGFALVPPDEIIKLEQVKITNYDGTKI 159 >4GI8-A nrPDB Length = 557 Score = 32.0 bits (71), Expect = 0.61, Method: Composition-based stats. Identities = 10/50 (20%), Positives = 18/50 (36%) Query: 382 NPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGPAIP 431 + RD +G G EP + + ++D Q+ + G P Sbjct: 120 DNPYRDYYFWRDGKDGHEPNNYPSFFGGSAWEKDPVTGQYYLHYLGRQQP 169 >1X53-A nrPDB Length = 145 Score = 32.0 bits (71), Expect = 0.71, Method: Composition-based stats. Identities = 21/123 (17%), Positives = 37/123 (30%), Gaps = 34/123 (27%) Query: 91 GSAMFSKIGKRTKCLTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNLDWVYNNTPVFFI 150 + + + T V + T+ RG KF+ +GN+ Sbjct: 16 KETFLTSPEELYRVFTTQELVQAFTHAPATLEADRG--GKFHMVDGNV------------ 61 Query: 151 RDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVMIL---------FSDRG 201 +F + P+ ++ M W F + PE A + + RG Sbjct: 62 --SGEFTDLV------PEKHI---VMKWRFKSWPEGHFATITLTFIDKNGETELCMEGRG 110 Query: 202 TPA 204 PA Sbjct: 111 IPA 113 >2J63-A nrPDB Length = 467 Score = 31.6 bits (70), Expect = 0.90, Method: Composition-based stats. Identities = 16/102 (15%), Positives = 34/102 (33%), Gaps = 6/102 (5%) Query: 184 PENQVAIHQV-MILFSDRGTPANYRSMHGYSGHTYKWSNKNG--DWHYVQVH---IKTDQ 237 P + +H++ + P+ G S H + W+ + Y + + K+ Q Sbjct: 316 PSMREYLHRLDTWATENAAVPSAAAMGSGSSPHGFIWAGDLNVAERDYDRYYAGTFKSMQ 375 Query: 238 GIKNLTIEEATKIAGSNPDYCQQDLFEAIQNGNYPSWTVYIQ 279 EE + D+F + P ++ + Q Sbjct: 376 ECSGFAPEERMSFRETMQRTNSVDIFRQLYPQAGPVYSFWSQ 417 >2DIE-A nrPDB Length = 485 Score = 31.2 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 35/82 (42%), Gaps = 5/82 (6%) Query: 333 PSTTVPYQEASADPVLQAR-LFSYADAHRYRLGPNFHQIPVNCPYASKFFNPAIRDGPMN 391 P+ VP ++ DP+LQAR ++Y H Y + H I + +P + Sbjct: 375 PTHGVPSMKSKIDPLLQARQTYAYGTQHDY---FDHHDI-IGWTREGDSSHPNSGLATIM 430 Query: 392 VNGNFGSEPTYLANDKSYTYIQ 413 +G G++ Y+ K+ + Sbjct: 431 SDGPGGNKWMYVGKHKAGQVWR 452 >4GGP-A nrPDB Length = 401 Score = 30.8 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 19/105 (18%), Positives = 35/105 (33%), Gaps = 20/105 (19%) Query: 241 NLTIEEATKIAGSNPDYCQQDLFEAIQNGNYPSWTVYIQTMTERDAKKLPFSVF------ 294 NL +EA K G L+ +G+ S + Q + E K + F + Sbjct: 100 NLAFDEAAKREG---------LYSVTIDGDAFSDEIKAQVIEEAKKKGIKFDLIVYSLAS 150 Query: 295 ----DLTKVWPQGQFPLRRVGKIVLNENPLNFFAQVEQAAFAPST 335 D L+ GK + F ++++ + P+ Sbjct: 151 PVRTDPDTGIMHKSV-LKPFGKTFTGKTVDPFTGELKEISAEPAN 194 >5U5I-A nrPDB Length = 278 Score = 30.8 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 17/32 (53%), Gaps = 2/32 (6%) Query: 197 FSDRGTPANYRSMHGYSGHTYKWSNKNGDWHY 228 + G P + ++G++ HTYK + +G + Sbjct: 201 MTRMGVPE--QHLNGHAFHTYKIISPDGTVFF 230 >2PNC-A nrPDB Length = 746 Score = 30.4 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 24/133 (18%), Positives = 41/133 (30%), Gaps = 24/133 (18%) Query: 107 RFSTVGGDKGSADTV---------RDPRGFATKFYTEEGNLDW--------VYNNTP--- 146 RFS V G++ ++ PR F +F E + NTP Sbjct: 305 RFS-VQGNRVASSLWTFSFGLGAFSGPRVFDVRFQGERLAYEISLQEAGAVYGGNTPAAM 363 Query: 147 -VFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVMILFS-DRGTPA 204 ++ +F R M W F+ + +H +F ++G P Sbjct: 364 LTRYMDSGFGMGYFATPLIRGVDCPYLATYMDWHFVVESQTPKTLHDAFCVFEQNKGLPL 423 Query: 205 NYRSMHGYSGHTY 217 R + H + Sbjct: 424 R-RHHSDFLSHYF 435 >1M53-A nrPDB Length = 570 Score = 30.4 bits (67), Expect = 2.1, Method: Composition-based stats. Identities = 11/70 (15%), Positives = 19/70 (27%), Gaps = 1/70 (1%) Query: 382 NPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQDRPIQQHQEVWNGPAIPY-HWATSPGD 440 N RD +G P + + Q+D Q+ + P +W Sbjct: 133 NNPYRDYYFWRDGKDNQPPNNYPSFFGGSAWQKDAKSGQYYLHYFARQQPDLNWDNPKVR 192 Query: 441 VDFVQARNLY 450 D + Sbjct: 193 EDLYAMLRFW 202 >4CNR-A nrPDB Length = 262 Score = 30.1 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 28/149 (18%), Positives = 52/149 (34%), Gaps = 28/149 (18%) Query: 105 LTRFSTVGGDKGSADTVRDPRGFATKFYTEEGNLDWVYNNTP----VFFIRDPSK----- 155 L ++T GD G+A ++P G A G V + P V D K Sbjct: 122 LVHWNTKYGDFGTA--AQEPDGLAVV-----GVFLKVGDANPALQKVLDALDSIKTKGKS 174 Query: 156 --FPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVMILFSDRGTPANYRSMHGYS 213 FP+F +P + L + +W + + + V + + + M + Sbjct: 175 TDFPNF------DPGSLLPNVLDYWTYPGSLTTPPLLESVTWIVLKEPISVSSQQMLKFR 228 Query: 214 GHTYKWSNKNGDW-HYVQVHIKTDQGIKN 241 + N G+ + + + Q +KN Sbjct: 229 TLNF---NAEGEPEELMLANWRPAQPLKN 254 >4GFV-A nrPDB Length = 297 Score = 30.1 bits (66), Expect = 2.7, Method: Composition-based stats. Identities = 24/82 (29%), Positives = 32/82 (39%), Gaps = 16/82 (19%) Query: 109 STVGGDKGSADTVRDPRGFATKFY----------TEEGNLDWVYNNTPVFFIRDPSKFPH 158 STV G + + VR R Y EEG+ D++ N FIR Sbjct: 44 STVAGSR--PENVRKNRYKDVLPYDQTRVILSLLQEEGHSDYINGN----FIRGVDGSLA 97 Query: 159 FIHTQKRNPQTNLRDADMFWDF 180 +I TQ P T L + W+F Sbjct: 98 YIATQGPLPHTLLDFWRLVWEF 119 >1U10-A nrPDB Length = 255 Score = 29.7 bits (65), Expect = 2.9, Method: Composition-based stats. Identities = 13/101 (12%), Positives = 30/101 (29%), Gaps = 5/101 (4%) Query: 163 QKRNPQTNLRDADMFWDFLTTPENQVAIHQVMILFSDRGTPANYRSMHGYSGHTYKWSNK 222 + + + D+ + +L D G PA R G++ H + Sbjct: 42 MRTDQRRYFGHPDLVMFIQRLSSQVSNLGMGTVLIGDMGMPAGGRFNGGHASHQTGL-DV 100 Query: 223 NGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDYCQQDLF 263 + + + Q L +A + + + L+ Sbjct: 101 DIFLQLPKTRWTSAQ----LLRPQALDLVSRDGKHVVSTLW 137 >4CN6-A nrPDB Length = 695 Score = 29.3 bits (64), Expect = 3.9, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 18/71 (25%), Gaps = 12/71 (16%) Query: 139 DWVYNNTPVFFIRDPSKFPHFIHTQKRNPQTNLRDADMFWDFLTTPENQVAIHQVMILFS 198 D V N +RDP + P T +R+ D Sbjct: 77 DAVGANV---VLRDPRG--------RPGPWTPMRELAPGTDRWGATVTAGETGTWSYTVE 125 Query: 199 DRGTP-ANYRS 208 G P +R Sbjct: 126 AWGDPVTTWRH 136 >1YWQ-A nrPDB Length = 200 Score = 29.3 bits (64), Expect = 4.6, Method: Composition-based stats. Identities = 10/43 (23%), Positives = 17/43 (39%) Query: 168 QTNLRDADMFWDFLTTPENQVAIHQVMILFSDRGTPANYRSMH 210 Q N + F + N + H V +L S G A+ + + Sbjct: 111 QENAPLYKDQFPFWSHQGNAMLQHTVWMLLSAEGIGASLQHYN 153 >1PHO-A nrPDB Length = 330 Score = 28.9 bits (63), Expect = 5.6, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 23/57 (40%), Gaps = 3/57 (5%) Query: 57 AHFNRENIPQRNPHAHGSGAFGYFEVTD---DITDICGSAMFSKIGKRTKCLTRFST 110 A+ N + ++N + G+G T D +I + +S+ K T F+ Sbjct: 186 AYTNSDRTNEQNLQSRGTGKRAEAWATGLKYDANNIYLATFYSETRKMTPITGGFAN 242 >2F3T-A nrPDB Length = 207 Score = 28.9 bits (63), Expect = 5.7, Method: Composition-based stats. Identities = 13/105 (12%), Positives = 30/105 (28%), Gaps = 1/105 (0%) Query: 412 IQQDRPIQQHQEVWNGPAIPYHWATSPGDVDFVQARNLYRVLGKQPG-QQKNLAYNIGIH 470 ++ V + P FV ++ + + + N Sbjct: 25 LKTQPLYDTQVSVSHTTRQPRPGEVHGEHYFFVNHDEFKEMISRDAFLEHAEVFGNYYGT 84 Query: 471 VEGACPQIQQRVYDMFARVDKGLSEAIKKVAEAKHASELSSNSKF 515 A Q+ D+F +D ++ I++ + + SK Sbjct: 85 SREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIFILPPSKI 129 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.306 0.132 0.367 Lambda K H 0.267 0.0409 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,839,067 Number of Sequences: 36641 Number of extensions: 924247 Number of successful extensions: 2157 Number of sequences better than 10.0: 45 Number of HSP's better than 10.0 without gapping: 52 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 1971 Number of HSP's gapped (non-prelim): 80 length of query: 515 length of database: 10,336,785 effective HSP length: 101 effective length of query: 414 effective length of database: 6,636,044 effective search space: 2747322216 effective search space used: 2747322216 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.0 bits) S2: 61 (28.1 bits)