BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P15144 (967 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5LHD-A nrPDB 1936 0.0 5LG6-A nrPDB 1517 0.0 4KXA-A nrPDB 552 e-157 3QNF-A nrPDB 495 e-140 5C97-A nrPDB 483 e-136 3SE6-A nrPDB 467 e-131 4WZ9-A nrPDB 425 e-119 1Z1W-A nrPDB 261 1e-69 3RJO-A nrPDB 154 1e-37 5Y1X-A nrPDB 107 3e-23 5DLL-A nrPDB 105 7e-23 5FWQ-A nrPDB 100 4e-21 4GAA-A nrPDB 95 1e-19 2XPY-A nrPDB 88 1e-17 3CIA-A nrPDB 84 3e-16 4QHP-A nrPDB 80 5e-15 5ZI5-A nrPDB 74 4e-13 4Q4I-A nrPDB 73 6e-13 1WST-A nrPDB 32 1.1 2FVL-A nrPDB 32 1.6 3ZUK-A nrPDB 31 2.8 2MP8-A nrPDB 30 6.2 2OCZ-A nrPDB 29 7.6 >5LHD-A nrPDB Length = 950 Score = 1936 bits (5015), Expect = 0.0, Method: Compositional matrix adjust. Identities = 932/932 (100%), Positives = 932/932 (100%) Query: 36 EKNKNANSSPVASTTPSASATTNPASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTP 95 EKNKNANSSPVASTTPSASATTNPASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTP Sbjct: 19 EKNKNANSSPVASTTPSASATTNPASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTP 78 Query: 96 NDRGLYVFKGSSTVRFTCKEATDVIIIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTEL 155 NDRGLYVFKGSSTVRFTCKEATDVIIIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTEL Sbjct: 79 NDRGLYVFKGSSTVRFTCKEATDVIIIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTEL 138 Query: 156 VEPTEYLVVHLKGSLVKDSQYEMDSEFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAA 215 VEPTEYLVVHLKGSLVKDSQYEMDSEFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAA Sbjct: 139 VEPTEYLVVHLKGSLVKDSQYEMDSEFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAA 198 Query: 216 DARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKM 275 DARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKM Sbjct: 199 DARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKM 258 Query: 276 STYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTP 335 STYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTP Sbjct: 259 STYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTP 318 Query: 336 YPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWF 395 YPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWF Sbjct: 319 YPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWF 378 Query: 396 GNLVTIEWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPL 455 GNLVTIEWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPL Sbjct: 379 GNLVTIEWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPL 438 Query: 456 STPASEINTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYL 515 STPASEINTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYL Sbjct: 439 STPASEINTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYL 498 Query: 516 NLWDHLQEAVNNRSIQLPTTVRDIMNRWTLQMGFPVITVDTSTGTLSQEHFLLDPDSNVT 575 NLWDHLQEAVNNRSIQLPTTVRDIMNRWTLQMGFPVITVDTSTGTLSQEHFLLDPDSNVT Sbjct: 499 NLWDHLQEAVNNRSIQLPTTVRDIMNRWTLQMGFPVITVDTSTGTLSQEHFLLDPDSNVT 558 Query: 576 RPSEFNYVWIVPITSIRDGRQQQDYWLIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYD 635 RPSEFNYVWIVPITSIRDGRQQQDYWLIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYD Sbjct: 559 RPSEFNYVWIVPITSIRDGRQQQDYWLIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYD 618 Query: 636 EENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQYMPW 695 EENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQYMPW Sbjct: 619 EENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQYMPW 678 Query: 696 EAALSSLSYFKLMFDRSEVYGPMKNYLKKQVTPLFIHFRNNTNNWREIPENLMDQYSEVN 755 EAALSSLSYFKLMFDRSEVYGPMKNYLKKQVTPLFIHFRNNTNNWREIPENLMDQYSEVN Sbjct: 679 EAALSSLSYFKLMFDRSEVYGPMKNYLKKQVTPLFIHFRNNTNNWREIPENLMDQYSEVN 738 Query: 756 AISTACSNGVPECEEMVSGLFKQWMENPNNNPIHPNLRSTVYCNAIAQGGEEEWDFAWEQ 815 AISTACSNGVPECEEMVSGLFKQWMENPNNNPIHPNLRSTVYCNAIAQGGEEEWDFAWEQ Sbjct: 739 AISTACSNGVPECEEMVSGLFKQWMENPNNNPIHPNLRSTVYCNAIAQGGEEEWDFAWEQ 798 Query: 816 FRNATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIRKQDATSTIISITNNVIGQGL 875 FRNATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIRKQDATSTIISITNNVIGQGL Sbjct: 799 FRNATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIRKQDATSTIISITNNVIGQGL 858 Query: 876 VWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTR 935 VWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTR Sbjct: 859 VWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTR 918 Query: 936 ALEQALEKTKANIKWVKENKEVVLQWFTENSK 967 ALEQALEKTKANIKWVKENKEVVLQWFTENSK Sbjct: 919 ALEQALEKTKANIKWVKENKEVVLQWFTENSK 950 >5LG6-A nrPDB Length = 968 Score = 1517 bits (3927), Expect = 0.0, Method: Compositional matrix adjust. Identities = 733/935 (78%), Positives = 816/935 (87%), Gaps = 7/935 (0%) Query: 34 SQEKNKNANSSPVASTTPSASATTNPASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYL 93 S EKNKNA P A T+P+ + T A TLDQSK WNRYRLP TL PDSY VTLRPYL Sbjct: 16 SPEKNKNAEHVPQAPTSPTITTTA----AITLDQSKPWNRYRLPTTLLPDSYNVTLRPYL 71 Query: 94 TPNDRGLYVFKGSSTVRFTCKEATDVIIIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKT 153 TPN GLY+FKG S VRF C+E TDVIIIHSKKLNYT +QGH VVLRGVG SQ P+ID+T Sbjct: 72 TPNADGLYIFKGKSIVRFICQEPTDVIIIHSKKLNYT-TQGHMVVLRGVGDSQVPEIDRT 130 Query: 154 ELVEPTEYLVVHLKGSLVKDSQYEMDSEFEGELADDLAGFYRSEYMEGNVRKVVATTQMQ 213 ELVE TEYLVVHLKGSL YEM+SEF+GELADDLAGFYRSEYMEGNV+KV+ATTQMQ Sbjct: 131 ELVELTEYLVVHLKGSLQPGHMYEMESEFQGELADDLAGFYRSEYMEGNVKKVLATTQMQ 190 Query: 214 AADARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTP 273 + DARKSFPCFDEPAMKA FNITLIHP +LTALSNM PKG STPL EDPNW+VTEF TTP Sbjct: 191 STDARKSFPCFDEPAMKATFNITLIHPNNLTALSNMPPKGSSTPLAEDPNWSVTEFETTP 250 Query: 274 KMSTYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYD 333 MSTYLLA+IVSEF V + A NGVLIRIWARP+AIA GHG YALNVTGPILNFFA HY+ Sbjct: 251 VMSTYLLAYIVSEFQSVNETAQNGVLIRIWARPNAIAEGHGMYALNVTGPILNFFANHYN 310 Query: 334 TPYPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQ 393 T YPLPKSDQI LPDFNAGAMENWGLVTYREN+LLFDP SSS SNKERVVTVIAHELAHQ Sbjct: 311 TSYPLPKSDQIALPDFNAGAMENWGLVTYRENALLFDPQSSSISNKERVVTVIAHELAHQ 370 Query: 394 WFGNLVTIEWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSH 453 WFGNLVT+ WWNDLWLNEGFASYVEYLGAD+AEPTWNLKDL+V DVYRVMAVDALASSH Sbjct: 371 WFGNLVTLAWWNDLWLNEGFASYVEYLGADHAEPTWNLKDLIVPGDVYRVMAVDALASSH 430 Query: 454 PLSTPASEINTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTI 513 PL+TPA E+NTPAQISE+FD+ISYSKGASV+RMLS+FL+ED+FK+GLASYLH FAYQNT Sbjct: 431 PLTTPAEEVNTPAQISEMFDSISYSKGASVIRMLSNFLTEDLFKEGLASYLHAFAYQNTT 490 Query: 514 YLNLWDHLQEAVNNR-SIQLPTTVRDIMNRWTLQMGFPVITVDTSTGTLSQEHFLLDPDS 572 YL+LW+HLQ+AV+ + SI+LP TVR IM+RWTLQMGFPVITVDT TG +SQ+HFLLD +S Sbjct: 491 YLDLWEHLQKAVDAQTSIRLPDTVRAIMDRWTLQMGFPVITVDTKTGNISQKHFLLDSES 550 Query: 573 NVTRPSEFNYVWIVPITSIRDGRQQQDYWLIDV-RAQNDLFSTSGNEWVLLNLNVTGYYR 631 NVTR S F+Y+WIVPI+SI++G Q YWL DV +AQNDLF T+ ++WVLLN+NVTGY++ Sbjct: 551 NVTRSSAFDYLWIVPISSIKNGVMQDHYWLRDVSQAQNDLFKTASDDWVLLNVNVTGYFQ 610 Query: 632 VNYDEENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQ 691 VNYDE+NWR IQ QLQ + S IPVINRAQ+I D+FNLA+AH VPVTLAL+NTLFL E++ Sbjct: 611 VNYDEDNWRMIQHQLQTNLSVIPVINRAQVIYDSFNLATAHMVPVTLALDNTLFLNGEKE 670 Query: 692 YMPWEAALSSLSYFKLMFDRSEVYGPMKNYLKKQVTPLFIHFRNNTNNWREIPENLMDQY 751 YMPW+AALSSLSYF LMFDRSEVYGPMK YL+KQV PLF HF T NW E PENLMDQY Sbjct: 671 YMPWQAALSSLSYFSLMFDRSEVYGPMKKYLRKQVEPLFQHFETLTKNWTERPENLMDQY 730 Query: 752 SEVNAISTACSNGVPECEEMVSGLFKQWMENPNNNPIHPNLRSTVYCNAIAQGGEEEWDF 811 SE+NAISTACSNG+P+CE + LF QWM +P NNPIHPNLRST+YCNAIAQGG+++WDF Sbjct: 731 SEINAISTACSNGLPQCENLAKTLFDQWMSDPENNPIHPNLRSTIYCNAIAQGGQDQWDF 790 Query: 812 AWEQFRNATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIRKQDATSTIISITNNVI 871 AW Q + A LVNEADKLR+ALACS E+W+LNRYL YTLNPDLIRKQDATSTI SI +NVI Sbjct: 791 AWGQLQQAQLVNEADKLRSALACSNEVWLLNRYLGYTLNPDLIRKQDATSTINSIASNVI 850 Query: 872 GQGLVWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQQLEQFKKDNEETGFG 931 GQ L WDFVQSNWKKLF DYGGGSFSFSNLIQ VTRRFS+E+ELQQLEQFKK+N + GFG Sbjct: 851 GQPLAWDFVQSNWKKLFQDYGGGSFSFSNLIQGVTRRFSSEFELQQLEQFKKNNMDVGFG 910 Query: 932 SGTRALEQALEKTKANIKWVKENKEVVLQWFTENS 966 SGTRALEQALEKTKANIKWVKENKEVVL WF E+S Sbjct: 911 SGTRALEQALEKTKANIKWVKENKEVVLNWFIEHS 945 >4KXA-A nrPDB Length = 888 Score = 552 bits (1423), Expect = e-157, Method: Compositional matrix adjust. Identities = 325/925 (35%), Positives = 508/925 (54%), Gaps = 74/925 (8%) Query: 59 PASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSSTVRFTCKEATD 118 PAS D+S W +RLP+ + P Y + ++P L + + G+ ++ T Sbjct: 4 PASE---DESGQWKNFRLPDFVNPVHYDLHVKPLLEED-----TYTGTVSISINLSAPTR 55 Query: 119 VIIIHSKKLNYT-LSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVVHLKGSLVK----- 172 + +H ++ T L + R P D+ ++ EY + Sbjct: 56 YLWLHLRETRITRLPELKR-----------PSGDQVQVRRCFEYKKQEYVVVEAEEELTP 104 Query: 173 ---DSQYEMDSEFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAM 229 D Y + EF G L L GFYR+ Y E K +A T + DARKSFPCFDEP Sbjct: 105 SSGDGLYLLTMEFAGWLNGSLVGFYRTTYTENGRVKSIAATDHEPTDARKSFPCFDEPNK 164 Query: 230 KAEFNITLIHPKDLTALSNM-LPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFD 288 KA + I++ HPK+ ALSNM + K S D W T F + MSTYL+ F V +FD Sbjct: 165 KATYTISITHPKEYGALSNMPVAKEESV----DDKWTRTTFEKSVPMSTYLVCFAVHQFD 220 Query: 289 YVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPD 348 V++ +++G + I+ +P +YA N+T + ++F ++ Y LPK D+I +PD Sbjct: 221 SVKRISNSGKPLTIYVQPEQ--KHTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPD 278 Query: 349 FNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLW 408 F GAMENWGL+TYRE +LL+DP S+SSN++RV TV+AHEL HQWFGN+VT++WW DLW Sbjct: 279 FGTGAMENWGLITYRETNLLYDPKESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLW 338 Query: 409 LNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQI 468 LNEGFAS+ E+LG ++AE W ++D M+L DV V D+L SSHP+ + TP +I Sbjct: 339 LNEGFASFFEFLGVNHAETDWQMRDQMLLEDVLPVQEDDSLMSSHPIIV---TVTTPDEI 395 Query: 469 SELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNR 528 + +FD ISYSKG+S+LRML ++ + F++G YL + ++N + W L+EA Sbjct: 396 TSVFDGISYSKGSSILRMLEDWIKPENFQKGCQMYLEKYQFKNAKTSDFWAALEEAS--- 452 Query: 529 SIQLPTTVRDIMNRWTLQMGFPVITVDTSTGTLSQEHFLLDPDSNVTR-PSEFNYVWIVP 587 +LP V+++M+ WT QMG+PV+ V+ ++Q+ FLLDP +N ++ PS+ Y W +P Sbjct: 453 --RLP--VKEVMDTWTRQMGYPVLNVN-GVKNITQKRFLLDPRANPSQPPSDLGYTWNIP 507 Query: 588 I--------TSIRDGRQQQDYWLIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYDEENW 639 + +S+ R +++ I + + N SGN ++ +N + G+YRVNY+ W Sbjct: 508 VKWTEDNITSSVLFNRSEKEG--ITLNSSN----PSGNAFLKINPDHIGFYRVNYEVATW 561 Query: 640 RKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQYMPWEAAL 699 I T L +H +RA +I+DAF LA A + +ALN T +L E ++PW+ + Sbjct: 562 DSIATALSLNHKTFSSADRASLIDDAFALARAQLLDYKVALNLTKYLKREENFLPWQRVI 621 Query: 700 SSLSYFKLMF-DRSEVYGPMKNYLKKQVTPLFIHFRNNTNNWREIPENLMDQYSEVNAIS 758 S+++Y MF D E+Y ++ Y + QV P+ ++ W + +++ + + + Sbjct: 622 SAVTYIISMFEDDKELYPMIEEYFQGQVKPI-----ADSLGWNDAGDHVT-KLLRSSVLG 675 Query: 759 TACSNGVPECEEMVSGLFKQWMENPNNNPIHPNLRSTVYCNAIAQGGEE-EWDFAWEQFR 817 AC G E S LF+QW+ + P+ NLR VY + G E W++ EQ++ Sbjct: 676 FACKMGDREALNNASSLFEQWLNGTVSLPV--NLRLLVYRYGMQNSGNEISWNYTLEQYQ 733 Query: 818 NATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIRKQDATSTIISITNNVIGQGLVW 877 +L E +KL LA K + +L+RYL + +LI+ QD + I I+ N G+ + W Sbjct: 734 KTSLAQEKEKLLYGLASVKNVTLLSRYLDLLKDTNLIKTQDVFTVIRYISYNSYGKNMAW 793 Query: 878 DFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTRAL 937 +++Q NW L N Y + + ++ + F+TE +L Q+E F + G G R Sbjct: 794 NWIQLNWDYLVNRYTLNNRNLGRIV-TIAEPFNTELQLWQMESFFAKYPQAGAGEKPR-- 850 Query: 938 EQALEKTKANIKWVKENKEVVLQWF 962 EQ LE K NI+W+K+++ + +WF Sbjct: 851 EQVLETVKNNIEWLKQHRNTIREWF 875 >3QNF-A nrPDB Length = 954 Score = 495 bits (1275), Expect = e-140, Method: Compositional matrix adjust. Identities = 315/946 (33%), Positives = 479/946 (50%), Gaps = 71/946 (7%) Query: 49 TTPSASATTNPASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSST 108 +TPS +T + + WN+ RLP + P Y + + LT F G++ Sbjct: 33 STPSWCQSTEASPKRSDGTPFPWNKIRLPEYVIPVHYDLLIHANLTT-----LTFWGTTK 87 Query: 109 VRFTCKEATDVIIIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVVHLKG 168 V T + T II+HS L Q R LR G + + L P + + L Sbjct: 88 VEITASQPTSTIILHSHHL-----QISRATLRKGAGERLSEEPLQVLEHPRQEQIALLAP 142 Query: 169 S-LVKDSQYEMDSEFEGELADDLAGFYRSEYM--EGNVRKVVATTQMQAADARKSFPCFD 225 L+ Y + + G L++ GFY+S Y EG +R ++A+TQ + AR +FPCFD Sbjct: 143 EPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELR-ILASTQFEPTAARMAFPCFD 201 Query: 226 EPAMKAEFNITLIHPKDLTALSNM-LPKGPSTP--LPEDPNWNVTEFHTTPKMSTYLLAF 282 EPA KA F+I + A+SNM L K + L ED F T KMSTYL+AF Sbjct: 202 EPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIED------HFDVTVKMSTYLVAF 255 Query: 283 IVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSD 342 I+S+F+ V K +GV + ++A P I DYAL+ +L F+ ++ PYPLPK D Sbjct: 256 IISDFESVSKITKSGVKVSVYAVPDKI--NQADYALDAAVTLLEFYEDYFSIPYPLPKQD 313 Query: 343 QIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIE 402 +PDF +GAMENWGL TYRE++LLFD SS+S+K + +AHELAHQWFGNLVT+E Sbjct: 314 LAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVTME 373 Query: 403 WWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEI 462 WWNDLWLNEGFA ++E++ P + D + M VDAL SSHP+STP + Sbjct: 374 WWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYF-FGKCFDAMEVDALNSSHPVSTP---V 429 Query: 463 NTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQ 522 PAQI E+FD +SY KGA +L ML +LS D FK G+ YL +Y+NT +LWD + Sbjct: 430 ENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWDSMA 489 Query: 523 EAVNNRSI--------------------QLPTTVRDIMNRWTLQMGFPVITVDTSTGT-- 560 + Q V+ +MN WTLQ GFP+IT+ T G Sbjct: 490 SICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITI-TVRGRNV 548 Query: 561 -LSQEHFLLDPDSNVTRPSEFNYVWIVPITSIRDGRQQQDYWLIDVRAQNDLFSTSGNEW 619 + QEH++ D + Y+W VP+T I +L+ + + L EW Sbjct: 549 HMKQEHYMKGSDG----APDTGYLWHVPLTFITSKSDMVHRFLLKTKT-DVLILPEEVEW 603 Query: 620 VLLNLNVTGYYRVNYDEENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLA 679 + N+ + GYY V+Y+++ W + L+ H+A+ +RA +IN+AF L S K+ + A Sbjct: 604 IKFNVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKA 663 Query: 680 LNNTLFLIEERQYMPWEAALSSL-SYFKLM--FDRSEVYGPMKNYLKKQVTPLFIHFRNN 736 L+ +L+L E + MP L+ L +KLM D +EV K +L + + L + Sbjct: 664 LDLSLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLI-----D 718 Query: 737 TNNWREIPENLMDQYSEVNAISTACSNGVPECEEMVSGLFKQWMENPNNNPIHPNLRSTV 796 W + ++ ++ + AC + C + G F++W E+ N + ++ V Sbjct: 719 KQTWTD-EGSVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAV 777 Query: 797 YCNAIAQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIRK 856 + A+ E WDF + +++ + E ++ AL ++ L L + D I+ Sbjct: 778 F--AVGAQSTEGWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKT 835 Query: 857 QDATSTIISITNNVIGQGLVWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQ 916 Q+ + I N +G L W F++ NW KL + GS S ++++ T +FST L+ Sbjct: 836 QEFPQILTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLE 895 Query: 917 QLEQFKKDNEETGFGSGTRALEQALEKTKANIKWVKENKEVVLQWF 962 +++ F +E GS R ++Q +E + NI W+ +N + + W Sbjct: 896 EVKGFFSSLKEN--GSQLRCVQQTIETIEENIGWMDKNFDKIRVWL 939 >5C97-A nrPDB Length = 912 Score = 483 bits (1242), Expect = e-136, Method: Compositional matrix adjust. Identities = 312/917 (34%), Positives = 481/917 (52%), Gaps = 68/917 (7%) Query: 71 WNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSSTVRFTCKEATDVIIIHSKKLNYT 130 W + RLP + P Y ++L P LT F+GS T+ + T II+HS N + Sbjct: 40 WAQIRLPTAVVPLRYELSLHPNLTS-----MTFRGSVTISVQALQVTWNIILHSTGHNIS 94 Query: 131 LSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVVHLKGSLVKDSQYEMDSEFEGELADDL 190 RV SQ + E + +V + +L+ Y + E+ ++ Sbjct: 95 -----RVTFMSAVSSQEKQAEILEYAYHGQIAIVAPE-ALLAGHNYTLKIEYSANISSSY 148 Query: 191 AGFYRSEYM-EGNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTALSNM 249 GFY Y E N +K A TQ + AR +FPCFDEPA KA F I +I + TALSNM Sbjct: 149 YGFYGFSYTDESNEKKYFAATQFEPLAARSAFPCFDEPAFKATFIIKIIRDEQYTALSNM 208 Query: 250 LPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQASNGVLIRIWARPSAI 309 PK S L D EF + KMSTYL+AFIV E + Q NG L+ I+A P I Sbjct: 209 -PKKSSVVL--DDGLVQDEFSESVKMSTYLVAFIVGEMKNL-SQDVNGTLVSIYAVPEKI 264 Query: 310 AAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLF 369 H YAL T +L FF +++ YPL K D + +PDF AGAMENWGL+T+RE +LL+ Sbjct: 265 GQVH--YALETTVKLLEFFQNYFEIQYPLKKLDLVAIPDFEAGAMENWGLLTFREETLLY 322 Query: 370 DPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEYLGADYAEPTW 429 D +SS ++++ V +IAHELAHQWFGNLVT++WWNDLWLNEGFA+++EY + Sbjct: 323 DSNTSSMADRKLVTKIIAHELAHQWFGNLVTMKWWNDLWLNEGFATFMEYFSLEKI---- 378 Query: 430 NLKDLMVLNDV----YRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKGASVLR 485 K+L D ++ M D+L SSHP+S S + + QI E+FD++SY KG+S+L Sbjct: 379 -FKELSSYEDFLDARFKTMKKDSLNSSHPIS---SSVQSSEQIEEMFDSLSYFKGSSLLL 434 Query: 486 MLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVRDIMNRWTL 545 ML ++LSEDVF+ + YLH +Y + +LWD E V N+++ V+ +M WTL Sbjct: 435 MLKTYLSEDVFQHAVVLYLHNHSYASIQSDDLWDSFNE-VTNQTLD----VKRMMKTWTL 489 Query: 546 QMGFPVITVDTSTGTL--SQEHFLLDPDSNVTRPSEFNYVWIVPITSIRDGRQQQDYWLI 603 Q GFP++TV L QE F L+ + +PS+ +Y+W +P++ + +GR Y + Sbjct: 490 QKGFPLVTVQKKGKELFIQQERFFLNMKPEI-QPSDTSYLWHIPLSYVTEGRNYSKYQSV 548 Query: 604 DV--RAQNDLFSTSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQLQRDHSAIPVINRAQI 661 + + + T WV +N+N+ GYY V+Y +++W + QL+ + + +RA + Sbjct: 549 SLLDKKSGVINLTEEVLWVKVNINMNGYYIVHYADDDWEALIHQLKINPYVLSDKDRANL 608 Query: 662 INDAFNLASAHKVPVTLALNNTLFLIEERQYMPWEAALSSLSYFKLMFDRSEVYGPMKNY 721 IN+ F LA KVP+ A + +L E P AL L+++ E G M + Sbjct: 609 INNIFELAGLGKVPLKRAFDLINYLGNENHTAPITEALFQTD---LIYNLLEKLGYM-DL 664 Query: 722 LKKQVTPLFIHFRNN----------TNNWREIPENLMDQYSEVNAISTACSNGVPECEEM 771 + VT +F +N T + RE+ L++ AC++ + C Sbjct: 665 ASRLVTRVFKLLQNQIQQQTWTDEGTPSMRELRSALLE---------FACTHNLGNCSTT 715 Query: 772 VSGLFKQWMENPNNNPIHPNLRSTVYCNAIAQGGEEEWDFAWEQFRNATLVNEADKLRAA 831 LF WM + + ++ +TV+ + ++ W F ++ + E +K+ A Sbjct: 716 AMKLFDDWMASNGTQSLPTDVMTTVF--KVGAKTDKGWSFLLGKYISIGSEAEKNKILEA 773 Query: 832 LACSKELWILNRYLSYTLNPDLIRKQDATSTIISITNNVIGQGLVWDFVQSNWKKLFNDY 891 LA S+++ L + +LN D R Q + I ++ + G L WDFV+ NW KL + Sbjct: 774 LASSEDVRKLYWLMKSSLNGDNFRTQKLSFIIRTVGRHFPGHLLAWDFVKENWNKLVQKF 833 Query: 892 GGGSFSFSNLIQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTRALEQALEKTKANIKWV 951 GS++ N++ T FST+ L +++ F ++ E F R +++ALE + NI+W+ Sbjct: 834 PLGSYTIQNIVAGSTYLFSTKTHLSEVQAFFENQSEATF--RLRCVQEALEVIQLNIQWM 891 Query: 952 KENKEVVLQWF-TENSK 967 ++N + + W TE S+ Sbjct: 892 EKNLKSLTWWLRTETSQ 908 >3SE6-A nrPDB Length = 967 Score = 467 bits (1202), Expect = e-131, Method: Compositional matrix adjust. Identities = 315/939 (33%), Positives = 469/939 (49%), Gaps = 83/939 (8%) Query: 71 WNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSSTVRFTCKEATDVIIIHSKKL--- 127 W RLP+ + P Y + + P LT D F S + AT II+HSK L Sbjct: 64 WQELRLPSVVIPLHYDLFVHPNLTSLD-----FVASEKIEVLVSNATQFIILHSKDLEIT 118 Query: 128 NYTLS--QGHRVVLRG--VGGSQPPDIDKTELVEPTEYLVVHLKGSLVKDSQYEMDSEFE 183 N TL + R + G + P ++ L+ P E L HLK Y + +F+ Sbjct: 119 NATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVP-EKLTPHLK--------YYVAMDFQ 169 Query: 184 GELADDLAGFYRSEYME-GNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKD 242 +L D GFY+S Y G +++A T + AR +FPCFDEP KA F+I + Sbjct: 170 AKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESR 229 Query: 243 LTALSNMLPKGPSTPLP----EDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQASNGV 298 ALSNM PK + L ED F TT KMSTYL+A+IV +F + S+GV Sbjct: 230 HIALSNM-PKVKTIELEGGLLED------HFETTVKMSTYLVAYIVCDFHSLSGFTSSGV 282 Query: 299 LIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWG 358 + I+A P H YAL + +L+F+ ++D YPL K D I +PDF GAMENWG Sbjct: 283 KVSIYASPDKRNQTH--YALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWG 340 Query: 359 LVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVE 418 L+TYRE SLLFDP +SS+S+K V VIAHELAHQWFGNLVT+EWWND+WLNEGFA Y+E Sbjct: 341 LITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLNEGFAKYME 400 Query: 419 YLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYS 478 + + P D LN + V+ D+L SS P+S PA TP QI E+FD +SY+ Sbjct: 401 LIAVNATYPELQFDDYF-LNVCFEVITKDSLNSSRPISKPA---ETPTQIQEMFDEVSYN 456 Query: 479 KGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEA----------VNNR 528 KGA +L ML FL E+ F++G+ YL F+Y+N +LW L + V + Sbjct: 457 KGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHS 516 Query: 529 SIQLPTT----------VRDIMNRWTLQMGFPVITV--DTSTGTLSQEHFLL-----DPD 571 ++ + V+++M WTLQ G P++ V D + L QE FL DP+ Sbjct: 517 DPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPE 576 Query: 572 SNVTRPSEFNYVWIVPITSIRDGRQQQDYWLIDVRAQNDLFSTSGNEWVLLNLNVTGYYR 631 R + Y+W +P+T ++ + + L WV N++ GYY Sbjct: 577 ---WRALQERYLWHIPLTYSTSSSNVIHRHILKSKT-DTLDLPEKTSWVKFNVDSNGYYI 632 Query: 632 VNYDEENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQ 691 V+Y+ W ++ TQL ++H+ + +R +I+D F L A ++ + AL+ T +L E Sbjct: 633 VHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETS 692 Query: 692 YMPWEAALSSLSYFKLMFDR---SEVYGPMKNYLKKQVTPLFIHFRNNTNNWREIPENLM 748 LS L F M DR S++ +K YL + P+ + +W + ++ Sbjct: 693 SPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVI-----DRQSWSD-KGSVW 746 Query: 749 DQYSEVNAISTACSNGVPECEEMVSGLFKQWMENPNNNPIHPNLRSTVYCNAIAQGGEEE 808 D+ + AC C + + LF QWME+ I ++ VY ++ Sbjct: 747 DRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVY--SVGAQTTAG 804 Query: 809 WDFAWEQFRNATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIRKQDATSTIISITN 868 W++ EQ+ + E +K+ AL+ SK L + + + +I+ Q+ + + +I Sbjct: 805 WNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIAR 864 Query: 869 NVIGQGLVWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQQLEQFKKDNEET 928 GQ L WDFV+ NW L + GS+ +I T FS++ +LQ+++ F + E Sbjct: 865 RPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQ 924 Query: 929 GFGSGTRALEQALEKTKANIKWVKENKEVVLQWFTENSK 967 GS + LE NIKW+++N + W N++ Sbjct: 925 --GSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNTR 961 >4WZ9-A nrPDB Length = 957 Score = 425 bits (1092), Expect = e-119, Method: Compositional matrix adjust. Identities = 274/796 (34%), Positives = 405/796 (50%), Gaps = 53/796 (6%) Query: 73 RYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSSTVRFTCKEATDVIIIHSKKLNYTLS 132 RYRLP T P Y + LR + N+R F G+ ++ +ATD +++H++ L +S Sbjct: 45 RYRLPTTSIPIHYDLHLRTEIHRNER---TFTGTVGIQLQVVQATDKLVMHNRGL--VMS 99 Query: 133 QGHRVVL-RGVGGSQPPDIDKTELVEPTEYLVVHLKGSLVKDSQYEMDSEFEGELADDLA 191 L GV G+ D + T + ++++ Y ++ F+G LA + Sbjct: 100 SAKVSSLPNGVTGAPTLIGDVQYSTDTTFEHITFTSPTILQPGTYLLEVAFQGRLATNDD 159 Query: 192 GFYRSEYMEGN-VRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTALSNML 250 GFY S Y+ N R+ +ATTQ ++ AR +FPC+DEP +KA F +++ H A+SNM Sbjct: 160 GFYVSSYVADNGERRYLATTQFESTSARMAFPCYDEPGLKATFTVSITHSLSYKAISNM- 218 Query: 251 PKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIA 310 P+ +T + D T F TP MSTYLLAF+VS+F A R++ RP+A Sbjct: 219 PQKTTTDIETD--MRTTFFEKTPAMSTYLLAFVVSDFQLRLSGAQ-----RVYVRPNAF- 270 Query: 311 AGHGDYALNVTGPILNFFAGHYDTPYP--LPKSDQIGLPDFNAGAMENWGLVTYRENSLL 368 +AL IL H PY +PK DQI +PDF AGAMENWGLVTYRE +LL Sbjct: 271 -NEATFALEAGVKILKVLDDHLGIPYDTYMPKLDQIAIPDFAAGAMENWGLVTYREQALL 329 Query: 369 FDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEYLGADYAEPT 428 F+P S+ K V T IAHE AHQWFGNLV+ EWW +WLNEGFA+ E+ D A P Sbjct: 330 FNPAVSTYRGKTNVATTIAHEYAHQWFGNLVSPEWWEYIWLNEGFATLYEFYALDMAYPG 389 Query: 429 WNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKGASVLRMLS 488 +L + M D AS+ P++ A+ TP +IS LFD ++Y K SVL M+ Sbjct: 390 QEYWELFNQQVIQYAMGQDGQASTRPMNWNAA---TPGEISALFDRVAYDKSGSVLNMMR 446 Query: 489 SFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLP--TTVRDIMNRWTLQ 546 L +D +K GL +YL A Q + L+ LQ A+ + + LP TV IM WT + Sbjct: 447 HVLGDDNWKAGLKAYLTDRALQGAVDEQLYAGLQSAIEGKGV-LPNGVTVAQIMRTWTNE 505 Query: 547 MGFPVITV----DTSTGTLSQEHFLLD---PDSNVTRPSEFNYVWIVPITSIRDGRQQ-- 597 G+PV+ V DT +SQE F D P++N +W++P + + Sbjct: 506 AGYPVLNVRRSYDTGDVIISQERFYNDRKVPNTN---------IWMIPYNYVHQAKADFN 556 Query: 598 --QDYWLIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQLQRDHSAIPV 655 D+ + +A + NEW++ N GYYRVNYDE NW I L + ++I Sbjct: 557 EFDDFQWLATKAARIETTVPANEWIVFNKQQVGYYRVNYDEHNWELITNALHENWASIHR 616 Query: 656 INRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQYMPWEAALSSLSYFKLMFDRSEVY 715 +NRAQ+I+DA+ LA + ++ + +AL +L ER+Y PW AA +L+YF + Y Sbjct: 617 LNRAQLIDDAYWLARSGRLDLRVALRFMTYLRNEREYAPWTAANVALTYFNNRLRGTAEY 676 Query: 716 GPMKNYLKKQVTPLFIHFRNNTNNWREIPENLMDQYSEVNAIST-ACSNGVPECEEMVSG 774 ++ + ++ + + P++ + V IST ACS G +C + Sbjct: 677 HNFLIFVDALIEDIYSLLTIDAVS----PDDTLLHKYLVQTISTWACSMGYTDCLMKTAA 732 Query: 775 LFKQWMENPNNNP-IHPNLRSTVYCNAIAQGGEEEWDFAWEQFRNATLVNEADKLRAALA 833 L K E P +HP++ S YC + E E+ + + + N+ + E L +L Sbjct: 733 LLKA--EASGTGPAVHPDIASVTYCYGMRSALESEFQYLYRKMMNSKNLAERTMLIDSLG 790 Query: 834 CSKELWILNRYLSYTL 849 CS L +L+ L Sbjct: 791 CSNNKEFLKAFLTTAL 806 >1Z1W-A nrPDB Length = 780 Score = 261 bits (667), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 170/511 (33%), Positives = 267/511 (52%), Gaps = 53/511 (10%) Query: 173 DSQ-YEMDSEFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKA 231 DSQ +++ F G+++D L+G Y + G + TT +A DAR+ FPC D PA KA Sbjct: 65 DSQPQKIEISFAGKVSDSLSGIYYAGRENGMI-----TTHFEATDARRMFPCVDHPAYKA 119 Query: 232 EFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVE 291 F IT++ KD A+SNM PK E V EF TP+MSTYLL + +F Y Sbjct: 120 VFAITVVIDKDYDAISNMPPK-----RIEVSERKVVEFQDTPRMSTYLLYVGIGKFRYEY 174 Query: 292 KQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNA 351 ++ + LI +++ Y L++ + F+ ++ PY LPK I +P+F A Sbjct: 175 EKYRDIDLI-----LASLKDIRSKYPLDMARKSVEFYENYFGIPYALPKMHLISVPEFGA 229 Query: 352 GAMENWGLVTYRENSLLFDPLSSSSSNKER-VVTVIAHELAHQWFGNLVTIEWWNDLWLN 410 GAMENWG +T+RE + D +S+ +R VIAHE+AHQWFG+LVT++WWNDLWLN Sbjct: 230 GAMENWGAITFRE--IYMDIAENSAVTVKRNSANVIAHEIAHQWFGDLVTMKWWNDLWLN 287 Query: 411 EGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISE 470 E FA+++ Y D P W+ ++ + D+L ++HP+ ++ P +IS+ Sbjct: 288 ESFATFMSYKTMDTLFPEWSFWGDFFVSRTSGALRSDSLKNTHPIEV---DVRDPDEISQ 344 Query: 471 LFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSI 530 +FD ISY KGAS+LRM+ + + F++G++ YL+ + N +LW +++ Sbjct: 345 IFDEISYGKGASILRMIEDYAGYEEFRKGISKYLNDHKFGNAEGSDLWTAIEDVSGK--- 401 Query: 531 QLPTTVRDIMNRWTLQMGFPVITVDTSTG--TLSQEHFLLDPDSNVTRPSEFNYVWIVPI 588 V+ +M W G+PVI + + T+ Q FLL+ E W VP+ Sbjct: 402 ----PVKRVMEYWIKNPGYPVIKLKRNGRKITMYQTRFLLN--------GEEEGRWPVPV 449 Query: 589 -TSIRDGRQQQDYWLIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQLQ 647 +DG ++ L++ A S + + +N + G+YRV YD+ + + Sbjct: 450 NIKKKDGVER---ILLEDEA-----SIEADGLIKINADSAGFYRVLYDDATFSDVMGHY- 500 Query: 648 RDHSAIPVINRAQIINDAFN-LASAHKVPVT 677 RD S ++R +++D F L S H P T Sbjct: 501 RDLSP---LDRIGLVDDLFAFLLSGHIDPET 528 >3RJO-A nrPDB Length = 419 Score = 154 bits (390), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 111/421 (26%), Positives = 201/421 (47%), Gaps = 22/421 (5%) Query: 548 GFPVITVDTSTGT---LSQEHFLLDPDSNVTRPSEFNYVWIVPITSIRDGRQQQDYWLID 604 GFP+IT+ T G + QEH++ D + Y+W VP+T I +L+ Sbjct: 1 GFPLITI-TVRGRNVHMKQEHYMKGSDG----APDTGYLWHVPLTFITSKSDMVHRFLLK 55 Query: 605 VRAQNDLFSTSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQLQRDHSAIPVINRAQIIND 664 + + L EW+ N+ + GYY V+Y+++ W + L+ H+A+ +RA +IN+ Sbjct: 56 TKT-DVLILPEEVEWIKFNVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINN 114 Query: 665 AFNLASAHKVPVTLALNNTLFLIEERQYMPWEAALSSL-SYFKLM--FDRSEVYGPMKNY 721 AF L S K+ + AL+ +L+L E + MP L+ L +KLM D +EV K + Sbjct: 115 AFQLVSIGKLSIEKALDLSLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAF 174 Query: 722 LKKQVTPLFIHFRNNTNNWREIPENLMDQYSEVNAISTACSNGVPECEEMVSGLFKQWME 781 L + + L + W + ++ ++ + AC + C + G F++W E Sbjct: 175 LIRLLRDLI-----DKQTWTD-EGSVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKE 228 Query: 782 NPNNNPIHPNLRSTVYCNAIAQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWIL 841 + N + ++ V+ A+ E WDF + +++ + E ++ AL ++ L Sbjct: 229 SNGNLSLPVDVTLAVF--AVGAQSTEGWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKL 286 Query: 842 NRYLSYTLNPDLIRKQDATSTIISITNNVIGQGLVWDFVQSNWKKLFNDYGGGSFSFSNL 901 L + D I+ Q+ + I N +G L W F++ NW KL + GS S +++ Sbjct: 287 QWLLDESFKGDKIKTQEFPQILTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHM 346 Query: 902 IQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTRALEQALEKTKANIKWVKENKEVVLQW 961 + T +FST L++++ F +E GS R ++Q +E + NI W+ +N + + W Sbjct: 347 VMGTTNQFSTRTRLEEVKGFFSSLKEN--GSQLRCVQQTIETIEENIGWMDKNFDKIRVW 404 Query: 962 F 962 Sbjct: 405 L 405 >5Y1X-A nrPDB Length = 914 Score = 107 bits (267), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 103/392 (26%), Positives = 164/392 (41%), Gaps = 46/392 (11%) Query: 134 GHRVVLRGVG-GSQPPDIDKTELVEPTEYL----VVHLKGSLVKDSQYEMDSE--FEGEL 186 G +V GVG I+ +LVE EY + + V S++ SE E Sbjct: 70 GEDLVFDGVGLKINEISINNKKLVEGEEYTYDNEFLTIFSKFVPKSKFAFSSEVIIHPET 129 Query: 187 ADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKDL--T 244 L G Y+S K + +Q +A R+ D P M A++++T+ K+ Sbjct: 130 NYALTGLYKS--------KNIIVSQCEATGFRRITFFIDRPDMMAKYDVTVTADKEKYPV 181 Query: 245 ALSN-------MLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFD-----YVEK 292 LSN +P G DP H P YL A + + Y+ K Sbjct: 182 LLSNGDKVNEFEIPGGRHGARFNDP-------HLKP---CYLFAVVAGDLKHLSATYITK 231 Query: 293 QASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAG 352 V + +++ ++ +AL + F ++ Y L + + + + DFN G Sbjct: 232 YTKKKVELYVFSEEKYVSKLQ--WALECLKKSMAFDEDYFGLEYDLSRLNLVAVSDFNVG 289 Query: 353 AMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEG 412 AMEN GL + NSLL +S + R++TV+ HE H + GN VT+ W L L EG Sbjct: 290 AMENKGLNIFNANSLLASKKNSIDFSYARILTVVGHEYFHNYTGNRVTLRDWFQLTLKEG 349 Query: 413 FASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELF 472 + E L ++ T + L+ V + +V L S PLS P + + + Sbjct: 350 LTVHRENLFSEEMTKTVTTR----LSHVDLLRSVQFLEDSSPLSHPIRP-ESYVSMENFY 404 Query: 473 DAISYSKGASVLRMLSSFLSEDVFKQGLASYL 504 Y KG+ V+RM + L E+ +K+G Y+ Sbjct: 405 TTTVYDKGSEVMRMYLTILGEEYYKKGFDIYI 436 >5DLL-A nrPDB Length = 867 Score = 105 bits (263), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 105/390 (26%), Positives = 170/390 (43%), Gaps = 44/390 (11%) Query: 190 LAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKDL--TALS 247 L G Y+S G+V +TQ +A RK D P + A F + +I K LS Sbjct: 118 LEGLYKS----GDV----FSTQCEATGFRKITYYLDRPDVMAAFTVKIIADKKKYPIILS 169 Query: 248 NMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEK----QASNGVLIRIW 303 N K S + ++ ++ V + K YL A + + ++ ++ V + I+ Sbjct: 170 NG-DKIDSGDISDNQHFAV--WKDPFKKPCYLFALVAGDLASIKDTYITKSQRKVSLEIY 226 Query: 304 ARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWGLVTYR 363 A I H YA+ + + + Y L + +PDFNAGAMEN GL + Sbjct: 227 AFKQDIDKCH--YAMQAVKDSMKWDEDRFGLEYDLDTFMIVAVPDFNAGAMENKGLNIFN 284 Query: 364 ENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEYLGAD 423 ++ +++ + E V +V+ HE H W G+ VT W L L EG + + Sbjct: 285 TKYIMASNKTATDKDFELVQSVVGHEYFHNWTGDRVTCRDWFQLSLKEGLTVFRD----- 339 Query: 424 YAEPTWNL--KDLMVLNDVYRV----MAVDALASSHPLSTPASEINTPAQISELFDAISY 477 E T +L +D+ ++DV + A DA SHP+ P S I +++ + Y Sbjct: 340 -QEFTSDLNSRDVKRIDDVRIIRSAQFAEDASPMSHPIR-PESYI----EMNNFYTVTVY 393 Query: 478 SKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVR 537 +KGA ++RM+ + L E+ F++G+ Y Q + + + +A NNR L Sbjct: 394 NKGAEIIRMIHTLLGEEGFQKGMKLYFERHDGQAVTCDDFVNAMADA-NNRDFSL----- 447 Query: 538 DIMNRWTLQMGFPVITVDTSTGTLSQEHFL 567 RW Q G P I V + SQ + L Sbjct: 448 --FKRWYAQSGTPNIKVSENYDASSQTYSL 475 >5FWQ-A nrPDB Length = 633 Score = 100 bits (248), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 85/306 (27%), Positives = 139/306 (45%), Gaps = 24/306 (7%) Query: 210 TQMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEF 269 +Q QA R PC D P++K + + PK+L AL + + G TP PEDP+ + +F Sbjct: 148 SQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDG-ETPDPEDPSRKIYKF 206 Query: 270 HTTPKMSTYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFA 329 + YL+A +V + +Q L+ W+ + Y + T +L A Sbjct: 207 IQKVPIPCYLIALVVGALE--SRQIGPRTLV--WSEKEQVEKSA--YEFSETESMLKI-A 259 Query: 330 GHYDTPYPLPKSDQIGLP-DFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAH 388 PY + D + LP F G MEN L T+ +LL + + + VIAH Sbjct: 260 EDLGGPYVWGQYDLLVLPPSFPYGGMENPCL-TFVTPTLL--------AGDKSLSNVIAH 310 Query: 389 ELAHQWFGNLVTIEWWNDLWLNEGFASYVE--YLGADYAEPTWNLKDLMVLNDVYRVMAV 446 E++H W GNLVT + W+ WLNEG Y+E G + E + L ++ +V Sbjct: 311 EISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQN--SV 368 Query: 447 DALASSHPLSTPASEINTPAQISELFDAISYSKGASVLRMLSSFL-SEDVFKQGLASYLH 505 +HP + ++ T + ++ Y KG ++L L L ++F L +Y+ Sbjct: 369 KTFGETHPFTKLVVDL-TDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVE 427 Query: 506 TFAYQN 511 F+Y++ Sbjct: 428 KFSYKS 433 >4GAA-A nrPDB Length = 609 Score = 95.1 bits (235), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 88/314 (28%), Positives = 137/314 (43%), Gaps = 40/314 (12%) Query: 210 TQMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEF 269 +Q QA R PC D P++K + + PK+L AL + L G + D N + F Sbjct: 130 SQCQATHCRSIIPCQDTPSVKFTYYSQVSVPKELMALMSALRDGELSE-QSDSNRKIYRF 188 Query: 270 HTTPKMSTYLLAFIVSEFDYVEKQASNGVLIRIWAR-----PSAIAAGHGD----YALNV 320 + +YL+A +V + G IW PS + YA ++ Sbjct: 189 KQNVPIPSYLIALVVGALE----GRKVGPRTTIWTEKELLEPSVYEFAETEKMLKYAEDL 244 Query: 321 TGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKE 380 GP + G YD LP P F G MEN L T+ ++L + Sbjct: 245 AGP---YVWGQYDL-LILP-------PSFPYGGMENPCL-TFVTPTVL--------AGDR 284 Query: 381 RVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEYL--GADYAEPTWNLKDLMVLN 438 + +VIAHE++H W GNLVT E W + WLNEG Y+E G Y E K L Sbjct: 285 SLASVIAHEISHSWTGNLVTNETWENFWLNEGHTVYLERRIDGRLYGEEFRQFKALGGWK 344 Query: 439 DVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKGASVLRMLSSFL-SEDVFK 497 ++ +V+ +++PL+ ++ + F ++ Y KG ++L L L ++F Sbjct: 345 ELQN--SVNTFGATNPLTNLVPNLHE-VDVDAAFSSVPYEKGFALLFYLEQLLGGPEIFL 401 Query: 498 QGLASYLHTFAYQN 511 L SY+ FA+++ Sbjct: 402 GFLKSYIQMFAFKS 415 >2XPY-A nrPDB Length = 632 Score = 88.2 bits (217), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 85/325 (26%), Positives = 137/325 (42%), Gaps = 52/325 (16%) Query: 210 TQMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPED--PNWNVT 267 +Q++A AR FPCFD P++K+ F ++ P LP S ED + N+ Sbjct: 144 SQLEAIHARSLFPCFDTPSVKSTFTASIESP---------LPVVFSGIRIEDTSKDTNIY 194 Query: 268 EFHTTPKMSTYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTG----- 322 F + YL+ + A G ++ P + ++ +V Sbjct: 195 RFEQKVPIPAYLIGIASGDL----SSAPIGPRSTVYTEPFRLKDCQWEFENDVEKFIQTA 250 Query: 323 --PILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKE 380 I + G YD + + + G ME+ + T+ +L+ + SN Sbjct: 251 EKIIFEYEWGTYDI--------LVNVDSYPYGGMESPNM-TFATPTLI----AHDRSN-- 295 Query: 381 RVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVE--YLGADYAEPTWNLKDLMVLN 438 + VIAHELAH W GNLVT WN WLNEG+ Y+E +GA + EPT + L+ + Sbjct: 296 --IDVIAHELAHSWSGNLVTNCSWNHFWLNEGWTVYLERRIIGAIHGEPTRHFSALIGWS 353 Query: 439 DVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKGASVLRMLSSFLS------ 492 D+ ++D++ ST +N + F + Y KG ++L L + L Sbjct: 354 DLQN--SIDSMKDPERFSTLVQNLNDNTDPDDAFSTVPYEKGFNLLFHLETILGGKAEFD 411 Query: 493 ---EDVFKQGLASYLHTFAYQNTIY 514 FK+ L TF + +T+Y Sbjct: 412 PFIRHYFKKFAKKSLDTFQFLDTLY 436 >3CIA-A nrPDB Length = 605 Score = 84.0 bits (206), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 95/353 (26%), Positives = 143/353 (40%), Gaps = 50/353 (14%) Query: 210 TQMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEF 269 +Q QA AR P D P+++ + + KDL A+ + P T D F Sbjct: 143 SQNQAIHARSWIPIQDTPSVRVTYTARITTDKDLLAVMSA-NNEPGTERDGD------YF 195 Query: 270 HTTPK-MSTYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPIL--N 326 + P+ + YL+A V + ++ G+ + +A+A A+ + Sbjct: 196 FSMPQAIPPYLIAIGVGDLEFKAMSHQTGIYAESYILDAAVAEFDDTQAMIDKAEQMYGK 255 Query: 327 FFAGHYDTPYPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVI 386 + G YD LP P F G MEN L F + + +K +V +I Sbjct: 256 YRWGRYDL-LMLP-------PSFPFGGMEN--------PRLSFITPTVVAGDKS-LVNLI 298 Query: 387 AHELAHQWFGNLVTIEWWNDLWLNEGFASYVE------YLGADYA--EPTWNLKDLMVLN 438 AHELAH W GNLVT E W DLWLNEGF SYVE G D A E +DL Sbjct: 299 AHELAHSWSGNLVTNESWRDLWLNEGFTSYVENRIMEAVFGTDRAVMEQALGAQDLNA-- 356 Query: 439 DVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQ 498 ++ +DA + + + + + F + Y KG L L + F Sbjct: 357 ---EILELDASDTQLYIDLKGRDPD------DAFSGVPYVKGQLFLMYLEEKFGRERFDA 407 Query: 499 GLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVRD-IMNRWTLQMGFP 550 + Y + A+Q+ N +L+ N + + P V D +N W + G P Sbjct: 408 FVLEYFDSHAFQSLGTDNFVKYLKA---NLTDKYPNIVSDNEINEWIFKAGLP 457 >4QHP-A nrPDB Length = 870 Score = 79.7 bits (195), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 57/214 (26%), Positives = 96/214 (44%), Gaps = 17/214 (7%) Query: 344 IGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEW 403 + + DFN GAMEN GL + +L D +++ ++ E + +V+ HE H W GN VT Sbjct: 252 VAVGDFNMGAMENKGLNIFNTKFVLADSRTATDTDFEGIESVVGHEYFHNWTGNRVTCRD 311 Query: 404 WNDLWLNEGFASY--VEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASE 461 W L L EG + E+ G + ++++ +L DA ++HP+ + E Sbjct: 312 WFQLSLKEGLTVFRDQEFSGDRASRAVRRIENIRLLRQ--HQFPEDAGPTAHPVRPASYE 369 Query: 462 INTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHL 521 +++ + Y KGA V+RM + L E+ F++G+ Y F + + D Sbjct: 370 -----EMNNFYTMTVYEKGAEVVRMYHTLLGEEGFQKGMKLY---FQRHDGQAVTCDDFR 421 Query: 522 QEAVNNRSIQLPTTVRDIMNRWTLQMGFPVITVD 555 + I L D W Q G PV+ + Sbjct: 422 AAMADANGINL-----DQFALWYSQAGTPVLEAE 450 >5ZI5-A nrPDB Length = 921 Score = 73.6 bits (179), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 91/386 (23%), Positives = 164/386 (42%), Gaps = 45/386 (11%) Query: 189 DLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKD--LTAL 246 DL G Y +E VA + ++ R+ F D P A + T+I ++ L Sbjct: 139 DLFGLYETEG--------VALVKAESEGLRRVFYLPDRPDNLATYKTTIIANQEDYPVLL 190 Query: 247 SN-MLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFD----YVEKQASNGVLIR 301 SN +L + PL +VT PK S YL A + Y + ++ + I Sbjct: 191 SNGVLIEKKELPLGL---HSVTWLDDVPKPS-YLFALVAGNLQRSVTYYQTKSGRELPIE 246 Query: 302 IWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWGLVT 361 + PSA + D+A V + + ++ L + G+ + +GA E GL Sbjct: 247 FYVPPSATS--KCDFAKEVLKEAMAWDERTFNLECALRQHMVAGVDKYASGASEPTGLNL 304 Query: 362 YRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEYLG 421 + +L P + + RV+ V+AHE H W G+ VTI W +L L EG ++ Sbjct: 305 FNTENLFASPETKTDLGILRVLEVVAHEFFHYWSGDRVTIRDWFNLPLKEGLTTFR---A 361 Query: 422 ADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKGA 481 A + E + D+ R++ L P + + + + L+ A +Y K A Sbjct: 362 AMFREELFG-------TDLIRLLDGKNLDERAPRQSAYTAVRS------LYTAAAYEKSA 408 Query: 482 SVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVRDIMN 541 + RM+ F+ ++ F + +A + F + + L D + E+++N S + +R ++ Sbjct: 409 DIFRMMMLFIGKEPFIEAVAKF---FKDNDGGAVTLEDFI-ESISNSSGK---DLRSFLS 461 Query: 542 RWTLQMGFPVITVDTSTGTLSQEHFL 567 W + G P + V ++++FL Sbjct: 462 -WFTESGIPELIVTDELNPDTKQYFL 486 >4Q4I-A nrPDB Length = 891 Score = 72.8 bits (177), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 57/211 (27%), Positives = 91/211 (43%), Gaps = 23/211 (10%) Query: 349 FNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLW 408 FN GAMEN GL + +L +++ + + VI HE H W GN VT W L Sbjct: 279 FNMGAMENKGLNIFNSKYVLARTDTATDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLS 338 Query: 409 LNEGFASYVEY-----LGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEIN 463 L EG + + LG+ N++ + L A DA +HP+ + Sbjct: 339 LKEGLTVFRDQEFSSDLGSRAVNRINNVRTMRGLQ-----FAEDASPMAHPIRP-----D 388 Query: 464 TPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQE 523 +++ + Y KGA V+RM+ + L E+ F++G+ Y F + D +Q Sbjct: 389 MVIEMNNFYTLTVYEKGAEVIRMIHTLLGEENFQKGMQLY---FERHDGSAATCDDFVQA 445 Query: 524 AVNNRSIQLPTTVRDIMNRWTLQMGFPVITV 554 + ++ L RW Q G P++TV Sbjct: 446 MEDASNVDLSH-----FRRWYSQSGTPIVTV 471 >1WST-A nrPDB Length = 417 Score = 32.3 bits (72), Expect = 1.1, Method: Compositional matrix adjust. Identities = 11/35 (31%), Positives = 19/35 (54%) Query: 850 NPDLIRKQDATSTIISITNNVIGQGLVWDFVQSNW 884 +P LIRK + I + N GQ + W +V++ + Sbjct: 269 HPHLIRKMEIAKQSIDLCTNTFGQAIAWKYVENGY 303 >2FVL-A nrPDB Length = 324 Score = 31.6 bits (70), Expect = 1.6, Method: Compositional matrix adjust. Identities = 37/139 (26%), Positives = 64/139 (46%), Gaps = 14/139 (10%) Query: 131 LSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVVHLKGSLVKDSQYEMDSEFEGELADDL 190 L+ GH + + G G PP++ + VE T+ + G DS Y ++E + LA Sbjct: 11 LNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIE--AGFRHIDSAYLYNNEEQVGLA--- 65 Query: 191 AGFYRSEYMEGNVRK--VVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTALS- 247 RS+ +G+V++ + T+++ + P +PA+++ + DL L Sbjct: 66 ---IRSKIADGSVKREDIFYTSKLWCTFFQ---PQMVQPALESSLKKLQLDYVDLYLLHF 119 Query: 248 NMLPKGPSTPLPEDPNWNV 266 M K TPLP+D N V Sbjct: 120 PMALKPGETPLPKDENGKV 138 >3ZUK-A nrPDB Length = 699 Score = 30.8 bits (68), Expect = 2.8, Method: Compositional matrix adjust. Identities = 13/46 (28%), Positives = 23/46 (50%), Gaps = 7/46 (15%) Query: 368 LFDPLSSSSSNKERVVTVIAHELAH-------QWFGNLVTIEWWND 406 FDP + ++N + VI HE+ H ++ G+ ++WW D Sbjct: 509 FFDPQADEAANYGGIGAVIGHEIGHGFDDQGAKYDGDGNLVDWWTD 554 >2MP8-A nrPDB Length = 64 Score = 29.6 bits (65), Expect = 6.2, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 22/42 (52%) Query: 852 DLIRKQDATSTIISITNNVIGQGLVWDFVQSNWKKLFNDYGG 893 D+I A +TII++ V+G GL+ + + K L YG Sbjct: 17 DIINTGSAVATIIALVTAVVGGGLITAGIVATAKSLIKKYGA 58 >2OCZ-A nrPDB Length = 231 Score = 29.3 bits (64), Expect = 7.6, Method: Compositional matrix adjust. Identities = 19/67 (28%), Positives = 35/67 (52%), Gaps = 7/67 (10%) Query: 699 LSSLSYFKLMFDRSEVYGP----MKNYLKKQVTPLFIHFRN---NTNNWREIPENLMDQY 751 LSS Y ++ + + +Y P + + K V + F N + +N+ E PENLM+ + Sbjct: 75 LSSQEYVDIIKEINAIYNPDYIDFEYFTHKSVFQEMLDFPNLILSYHNFEETPENLMEAF 134 Query: 752 SEVNAIS 758 SE+ ++ Sbjct: 135 SEMTKLA 141 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5LHD-A nrPDB 1309 0.0 5LG6-A nrPDB 1252 0.0 3QNF-A nrPDB 1085 0.0 3SE6-A nrPDB 1017 0.0 5C97-A nrPDB 983 0.0 4KXA-A nrPDB 973 0.0 4WZ9-A nrPDB 817 0.0 3RJO-A nrPDB 524 e-149 1Z1W-A nrPDB 524 e-149 5DLL-A nrPDB 388 e-108 5Y1X-A nrPDB 376 e-104 4QHP-A nrPDB 357 1e-98 4Q4I-A nrPDB 352 5e-97 5FWQ-A nrPDB 336 3e-92 5ZI5-A nrPDB 321 1e-87 4GAA-A nrPDB 309 6e-84 2XPY-A nrPDB 294 2e-79 3CIA-A nrPDB 286 3e-77 Sequences not found previously or not previously below threshold: 4FGM-A nrPDB 45 2e-04 3ZUK-A nrPDB 38 0.015 4RCO-A nrPDB 37 0.048 1BQB-A nrPDB 35 0.13 4XBH-A nrPDB 35 0.16 3SQR-A nrPDB 34 0.22 4WNR-A nrPDB 34 0.37 4CTH-A nrPDB 34 0.39 3OSL-A nrPDB 33 0.50 3NIV-A nrPDB 31 1.9 3MDV-A nrPDB 31 2.9 4CDB-A nrPDB 31 3.7 4AKR-A nrPDB 30 4.1 5G5P-A nrPDB 29 7.1 1WB0-A nrPDB 29 8.2 >5LHD-A nrPDB Length = 950 Score = 1309 bits (3386), Expect = 0.0, Method: Composition-based stats. Identities = 932/932 (100%), Positives = 932/932 (100%) Query: 36 EKNKNANSSPVASTTPSASATTNPASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTP 95 EKNKNANSSPVASTTPSASATTNPASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTP Sbjct: 19 EKNKNANSSPVASTTPSASATTNPASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTP 78 Query: 96 NDRGLYVFKGSSTVRFTCKEATDVIIIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTEL 155 NDRGLYVFKGSSTVRFTCKEATDVIIIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTEL Sbjct: 79 NDRGLYVFKGSSTVRFTCKEATDVIIIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTEL 138 Query: 156 VEPTEYLVVHLKGSLVKDSQYEMDSEFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAA 215 VEPTEYLVVHLKGSLVKDSQYEMDSEFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAA Sbjct: 139 VEPTEYLVVHLKGSLVKDSQYEMDSEFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAA 198 Query: 216 DARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKM 275 DARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKM Sbjct: 199 DARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKM 258 Query: 276 STYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTP 335 STYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTP Sbjct: 259 STYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTP 318 Query: 336 YPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWF 395 YPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWF Sbjct: 319 YPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWF 378 Query: 396 GNLVTIEWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPL 455 GNLVTIEWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPL Sbjct: 379 GNLVTIEWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPL 438 Query: 456 STPASEINTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYL 515 STPASEINTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYL Sbjct: 439 STPASEINTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYL 498 Query: 516 NLWDHLQEAVNNRSIQLPTTVRDIMNRWTLQMGFPVITVDTSTGTLSQEHFLLDPDSNVT 575 NLWDHLQEAVNNRSIQLPTTVRDIMNRWTLQMGFPVITVDTSTGTLSQEHFLLDPDSNVT Sbjct: 499 NLWDHLQEAVNNRSIQLPTTVRDIMNRWTLQMGFPVITVDTSTGTLSQEHFLLDPDSNVT 558 Query: 576 RPSEFNYVWIVPITSIRDGRQQQDYWLIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYD 635 RPSEFNYVWIVPITSIRDGRQQQDYWLIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYD Sbjct: 559 RPSEFNYVWIVPITSIRDGRQQQDYWLIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYD 618 Query: 636 EENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQYMPW 695 EENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQYMPW Sbjct: 619 EENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQYMPW 678 Query: 696 EAALSSLSYFKLMFDRSEVYGPMKNYLKKQVTPLFIHFRNNTNNWREIPENLMDQYSEVN 755 EAALSSLSYFKLMFDRSEVYGPMKNYLKKQVTPLFIHFRNNTNNWREIPENLMDQYSEVN Sbjct: 679 EAALSSLSYFKLMFDRSEVYGPMKNYLKKQVTPLFIHFRNNTNNWREIPENLMDQYSEVN 738 Query: 756 AISTACSNGVPECEEMVSGLFKQWMENPNNNPIHPNLRSTVYCNAIAQGGEEEWDFAWEQ 815 AISTACSNGVPECEEMVSGLFKQWMENPNNNPIHPNLRSTVYCNAIAQGGEEEWDFAWEQ Sbjct: 739 AISTACSNGVPECEEMVSGLFKQWMENPNNNPIHPNLRSTVYCNAIAQGGEEEWDFAWEQ 798 Query: 816 FRNATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIRKQDATSTIISITNNVIGQGL 875 FRNATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIRKQDATSTIISITNNVIGQGL Sbjct: 799 FRNATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIRKQDATSTIISITNNVIGQGL 858 Query: 876 VWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTR 935 VWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTR Sbjct: 859 VWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTR 918 Query: 936 ALEQALEKTKANIKWVKENKEVVLQWFTENSK 967 ALEQALEKTKANIKWVKENKEVVLQWFTENSK Sbjct: 919 ALEQALEKTKANIKWVKENKEVVLQWFTENSK 950 >5LG6-A nrPDB Length = 968 Score = 1252 bits (3238), Expect = 0.0, Method: Composition-based stats. Identities = 731/935 (78%), Positives = 815/935 (87%), Gaps = 7/935 (0%) Query: 34 SQEKNKNANSSPVASTTPSASATTNPASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYL 93 S EKNKNA P A T+P+ +A TLDQSK WNRYRLP TL PDSY VTLRPYL Sbjct: 16 SPEKNKNAEHVPQAPTSPT----ITTTAAITLDQSKPWNRYRLPTTLLPDSYNVTLRPYL 71 Query: 94 TPNDRGLYVFKGSSTVRFTCKEATDVIIIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKT 153 TPN GLY+FKG S VRF C+E TDVIIIHSKKLNYT +QGH VVLRGVG SQ P+ID+T Sbjct: 72 TPNADGLYIFKGKSIVRFICQEPTDVIIIHSKKLNYT-TQGHMVVLRGVGDSQVPEIDRT 130 Query: 154 ELVEPTEYLVVHLKGSLVKDSQYEMDSEFEGELADDLAGFYRSEYMEGNVRKVVATTQMQ 213 ELVE TEYLVVHLKGSL YEM+SEF+GELADDLAGFYRSEYMEGNV+KV+ATTQMQ Sbjct: 131 ELVELTEYLVVHLKGSLQPGHMYEMESEFQGELADDLAGFYRSEYMEGNVKKVLATTQMQ 190 Query: 214 AADARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTP 273 + DARKSFPCFDEPAMKA FNITLIHP +LTALSNM PKG STPL EDPNW+VTEF TTP Sbjct: 191 STDARKSFPCFDEPAMKATFNITLIHPNNLTALSNMPPKGSSTPLAEDPNWSVTEFETTP 250 Query: 274 KMSTYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYD 333 MSTYLLA+IVSEF V + A NGVLIRIWARP+AIA GHG YALNVTGPILNFFA HY+ Sbjct: 251 VMSTYLLAYIVSEFQSVNETAQNGVLIRIWARPNAIAEGHGMYALNVTGPILNFFANHYN 310 Query: 334 TPYPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQ 393 T YPLPKSDQI LPDFNAGAMENWGLVTYREN+LLFDP SSS SNKERVVTVIAHELAHQ Sbjct: 311 TSYPLPKSDQIALPDFNAGAMENWGLVTYRENALLFDPQSSSISNKERVVTVIAHELAHQ 370 Query: 394 WFGNLVTIEWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSH 453 WFGNLVT+ WWNDLWLNEGFASYVEYLGAD+AEPTWNLKDL+V DVYRVMAVDALASSH Sbjct: 371 WFGNLVTLAWWNDLWLNEGFASYVEYLGADHAEPTWNLKDLIVPGDVYRVMAVDALASSH 430 Query: 454 PLSTPASEINTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTI 513 PL+TPA E+NTPAQISE+FD+ISYSKGASV+RMLS+FL+ED+FK+GLASYLH FAYQNT Sbjct: 431 PLTTPAEEVNTPAQISEMFDSISYSKGASVIRMLSNFLTEDLFKEGLASYLHAFAYQNTT 490 Query: 514 YLNLWDHLQEAVNNRS-IQLPTTVRDIMNRWTLQMGFPVITVDTSTGTLSQEHFLLDPDS 572 YL+LW+HLQ+AV+ ++ I+LP TVR IM+RWTLQMGFPVITVDT TG +SQ+HFLLD +S Sbjct: 491 YLDLWEHLQKAVDAQTSIRLPDTVRAIMDRWTLQMGFPVITVDTKTGNISQKHFLLDSES 550 Query: 573 NVTRPSEFNYVWIVPITSIRDGRQQQDYWLIDV-RAQNDLFSTSGNEWVLLNLNVTGYYR 631 NVTR S F+Y+WIVPI+SI++G Q YWL DV +AQNDLF T+ ++WVLLN+NVTGY++ Sbjct: 551 NVTRSSAFDYLWIVPISSIKNGVMQDHYWLRDVSQAQNDLFKTASDDWVLLNVNVTGYFQ 610 Query: 632 VNYDEENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQ 691 VNYDE+NWR IQ QLQ + S IPVINRAQ+I D+FNLA+AH VPVTLAL+NTLFL E++ Sbjct: 611 VNYDEDNWRMIQHQLQTNLSVIPVINRAQVIYDSFNLATAHMVPVTLALDNTLFLNGEKE 670 Query: 692 YMPWEAALSSLSYFKLMFDRSEVYGPMKNYLKKQVTPLFIHFRNNTNNWREIPENLMDQY 751 YMPW+AALSSLSYF LMFDRSEVYGPMK YL+KQV PLF HF T NW E PENLMDQY Sbjct: 671 YMPWQAALSSLSYFSLMFDRSEVYGPMKKYLRKQVEPLFQHFETLTKNWTERPENLMDQY 730 Query: 752 SEVNAISTACSNGVPECEEMVSGLFKQWMENPNNNPIHPNLRSTVYCNAIAQGGEEEWDF 811 SE+NAISTACSNG+P+CE + LF QWM +P NNPIHPNLRST+YCNAIAQGG+++WDF Sbjct: 731 SEINAISTACSNGLPQCENLAKTLFDQWMSDPENNPIHPNLRSTIYCNAIAQGGQDQWDF 790 Query: 812 AWEQFRNATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIRKQDATSTIISITNNVI 871 AW Q + A LVNEADKLR+ALACS E+W+LNRYL YTLNPDLIRKQDATSTI SI +NVI Sbjct: 791 AWGQLQQAQLVNEADKLRSALACSNEVWLLNRYLGYTLNPDLIRKQDATSTINSIASNVI 850 Query: 872 GQGLVWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQQLEQFKKDNEETGFG 931 GQ L WDFVQSNWKKLF DYGGGSFSFSNLIQ VTRRFS+E+ELQQLEQFKK+N + GFG Sbjct: 851 GQPLAWDFVQSNWKKLFQDYGGGSFSFSNLIQGVTRRFSSEFELQQLEQFKKNNMDVGFG 910 Query: 932 SGTRALEQALEKTKANIKWVKENKEVVLQWFTENS 966 SGTRALEQALEKTKANIKWVKENKEVVL WF E+S Sbjct: 911 SGTRALEQALEKTKANIKWVKENKEVVLNWFIEHS 945 >3QNF-A nrPDB Length = 954 Score = 1085 bits (2805), Expect = 0.0, Method: Composition-based stats. Identities = 305/941 (32%), Positives = 469/941 (49%), Gaps = 61/941 (6%) Query: 49 TTPSASATTNPASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSST 108 +TPS +T + + WN+ RLP + P Y + + LT F G++ Sbjct: 33 STPSWCQSTEASPKRSDGTPFPWNKIRLPEYVIPVHYDLLIHANLTT-----LTFWGTTK 87 Query: 109 VRFTCKEATDVIIIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVVHLKG 168 V T + T II+HS L Q R LR G + + L P + + L Sbjct: 88 VEITASQPTSTIILHSHHL-----QISRATLRKGAGERLSEEPLQVLEHPRQEQIALLAP 142 Query: 169 S-LVKDSQYEMDSEFEGELADDLAGFYRSEYME-GNVRKVVATTQMQAADARKSFPCFDE 226 L+ Y + + G L++ GFY+S Y +++A+TQ + AR +FPCFDE Sbjct: 143 EPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILASTQFEPTAARMAFPCFDE 202 Query: 227 PAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSE 286 PA KA F+I + A+SNM T F T KMSTYL+AFI+S+ Sbjct: 203 PAFKASFSIKIRREPRHLAISNMPLVKSVTVAE---GLIEDHFDVTVKMSTYLVAFIISD 259 Query: 287 FDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGL 346 F+ V K +GV + ++A P I DYAL+ +L F+ ++ PYPLPK D + Sbjct: 260 FESVSKITKSGVKVSVYAVPDKI--NQADYALDAAVTLLEFYEDYFSIPYPLPKQDLAAI 317 Query: 347 PDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWND 406 PDF +GAMENWGL TYRE++LLFD SS+S+K + +AHELAHQWFGNLVT+EWWND Sbjct: 318 PDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVTMEWWND 377 Query: 407 LWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPA 466 LWLNEGFA ++E++ P + D + M VDAL SSHP+STP + PA Sbjct: 378 LWLNEGFAKFMEFVSVSVTHPELKVGDYF-FGKCFDAMEVDALNSSHPVSTP---VENPA 433 Query: 467 QISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVN 526 QI E+FD +SY KGA +L ML +LS D FK G+ YL +Y+NT +LWD + Sbjct: 434 QIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWDSMASICP 493 Query: 527 NRSIQ--------------------LPTTVRDIMNRWTLQMGFPVITVDTSTGT--LSQE 564 ++ V+ +MN WTLQ GFP+IT+ + QE Sbjct: 494 TDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGRNVHMKQE 553 Query: 565 HFLLDPDSNVTRPSEFNYVWIVPITSIRDGRQQQDYWLIDVRAQNDLFSTSGNEWVLLNL 624 H++ D + Y+W VP+T I +L+ + + L EW+ N+ Sbjct: 554 HYMKGSDG----APDTGYLWHVPLTFITSKSDMVHRFLLKTKT-DVLILPEEVEWIKFNV 608 Query: 625 NVTGYYRVNYDEENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLALNNTL 684 + GYY V+Y+++ W + L+ H+A+ +RA +IN+AF L S K+ + AL+ +L Sbjct: 609 GMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDLSL 668 Query: 685 FLIEERQYMPWEAALSSL-SYFKLM--FDRSEVYGPMKNYLKKQVTPLFIHFRNNTNNWR 741 +L E + MP L+ L +KLM D +EV K +L + + L + W Sbjct: 669 YLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLI-----DKQTWT 723 Query: 742 EIPENLMDQYSEVNAISTACSNGVPECEEMVSGLFKQWMENPNNNPIHPNLRSTVYCNAI 801 + ++ ++ + AC + C + G F++W E+ N + ++ V+ A+ Sbjct: 724 D-EGSVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVF--AV 780 Query: 802 AQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIRKQDATS 861 E WDF + +++ + E ++ AL ++ L L + D I+ Q+ Sbjct: 781 GAQSTEGWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQ 840 Query: 862 TIISITNNVIGQGLVWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQQLEQF 921 + I N +G L W F++ NW KL + GS S ++++ T +FST L++++ F Sbjct: 841 ILTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGF 900 Query: 922 KKDNEETGFGSGTRALEQALEKTKANIKWVKENKEVVLQWF 962 +E GS R ++Q +E + NI W+ +N + + W Sbjct: 901 FSSLKEN--GSQLRCVQQTIETIEENIGWMDKNFDKIRVWL 939 >3SE6-A nrPDB Length = 967 Score = 1017 bits (2630), Expect = 0.0, Method: Composition-based stats. Identities = 305/952 (32%), Positives = 461/952 (48%), Gaps = 63/952 (6%) Query: 48 STTPSASATTNPASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSS 107 ++ + T + W RLP+ + P Y + + P LT D F S Sbjct: 41 PSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLD-----FVASE 95 Query: 108 TVRFTCKEATDVIIIHSKKL---NYTLSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVV 164 + AT II+HSK L N TL G + L P + Sbjct: 96 KIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGK------ELKVLSYPAHEQIA 149 Query: 165 HLKGSLVKDS-QYEMDSEFEGELADDLAGFYRSEYME-GNVRKVVATTQMQAADARKSFP 222 L + +Y + +F+ +L D GFY+S Y G +++A T + AR +FP Sbjct: 150 LLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFP 209 Query: 223 CFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAF 282 CFDEP KA F+I + ALSNM PK + L F TT KMSTYL+A+ Sbjct: 210 CFDEPLFKANFSIKIRRESRHIALSNM-PKVKTIELEG--GLLEDHFETTVKMSTYLVAY 266 Query: 283 IVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSD 342 IV +F + S+GV + I+A P H YAL + +L+F+ ++D YPL K D Sbjct: 267 IVCDFHSLSGFTSSGVKVSIYASPDKRNQTH--YALQASLKLLDFYEKYFDIYYPLSKLD 324 Query: 343 QIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIE 402 I +PDF GAMENWGL+TYRE SLLFDP +SS+S+K V VIAHELAHQWFGNLVT+E Sbjct: 325 LIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTME 384 Query: 403 WWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEI 462 WWND+WLNEGFA Y+E + + P D LN + V+ D+L SS P+S PA Sbjct: 385 WWNDIWLNEGFAKYMELIAVNATYPELQFDDYF-LNVCFEVITKDSLNSSRPISKPA--- 440 Query: 463 NTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQ 522 TP QI E+FD +SY+KGA +L ML FL E+ F++G+ YL F+Y+N +LW L Sbjct: 441 ETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLS 500 Query: 523 EAV----------NNRSIQLPTT----------VRDIMNRWTLQMGFPVITV--DTSTGT 560 + + ++ + V+++M WTLQ G P++ V D + Sbjct: 501 NSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLR 560 Query: 561 LSQEHFLLD--PDSNVTRPSEFNYVWIVPITSIRDGRQQQDYWLIDVRAQNDLFSTSGNE 618 L QE FL + R + Y+W +P+T ++ + + L Sbjct: 561 LQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKT-DTLDLPEKTS 619 Query: 619 WVLLNLNVTGYYRVNYDEENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTL 678 WV N++ GYY V+Y+ W ++ TQL ++H+ + +R +I+D F L A ++ + Sbjct: 620 WVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDK 679 Query: 679 ALNNTLFLIEERQYMPWEAALSSLSYFKLMFDR---SEVYGPMKNYLKKQVTPLFIHFRN 735 AL+ T +L E LS L F M DR S++ +K YL + P+ Sbjct: 680 ALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVI----- 734 Query: 736 NTNNWREIPENLMDQYSEVNAISTACSNGVPECEEMVSGLFKQWMENPNNNPIHPNLRST 795 + +W + ++ D+ + AC C + + LF QWME+ I ++ Sbjct: 735 DRQSWSD-KGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKI 793 Query: 796 VYCNAIAQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIR 855 VY ++ W++ EQ+ + E +K+ AL+ SK L + + + +I+ Sbjct: 794 VY--SVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIK 851 Query: 856 KQDATSTIISITNNVIGQGLVWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYEL 915 Q+ + + +I GQ L WDFV+ NW L + GS+ +I T FS++ +L Sbjct: 852 TQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKL 911 Query: 916 QQLEQFKKDNEETGFGSGTRALEQALEKTKANIKWVKENKEVVLQWFTENSK 967 Q+++ F + E GS + LE NIKW+++N + W N++ Sbjct: 912 QEVKLFFESLEAQ--GSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNTR 961 >5C97-A nrPDB Length = 912 Score = 983 bits (2540), Expect = 0.0, Method: Composition-based stats. Identities = 306/917 (33%), Positives = 475/917 (51%), Gaps = 44/917 (4%) Query: 59 PASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSSTVRFTCKEATD 118 + T + W + RLP + P Y ++L P LT F+GS T+ + T Sbjct: 28 AETGATNGKLFPWAQIRLPTAVVPLRYELSLHPNLTS-----MTFRGSVTISVQALQVTW 82 Query: 119 VIIIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVVHLKGSLVKDSQYEM 178 II+HS N + RV SQ + E + +V + +L+ Y + Sbjct: 83 NIILHSTGHNIS-----RVTFMSAVSSQEKQAEILEYAYHGQIAIVAPE-ALLAGHNYTL 136 Query: 179 DSEFEGELADDLAGFYRSEYM-EGNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITL 237 E+ ++ GFY Y E N +K A TQ + AR +FPCFDEPA KA F I + Sbjct: 137 KIEYSANISSSYYGFYGFSYTDESNEKKYFAATQFEPLAARSAFPCFDEPAFKATFIIKI 196 Query: 238 IHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQASNG 297 I + TALSNM PK S L D EF + KMSTYL+AFIV E + Q NG Sbjct: 197 IRDEQYTALSNM-PKKSSVVL--DDGLVQDEFSESVKMSTYLVAFIVGEMKNL-SQDVNG 252 Query: 298 VLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENW 357 L+ I+A P I H YAL T +L FF +++ YPL K D + +PDF AGAMENW Sbjct: 253 TLVSIYAVPEKIGQVH--YALETTVKLLEFFQNYFEIQYPLKKLDLVAIPDFEAGAMENW 310 Query: 358 GLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYV 417 GL+T+RE +LL+D +SS ++++ V +IAHELAHQWFGNLVT++WWNDLWLNEGFA+++ Sbjct: 311 GLLTFREETLLYDSNTSSMADRKLVTKIIAHELAHQWFGNLVTMKWWNDLWLNEGFATFM 370 Query: 418 EYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISY 477 EY + + + L+ ++ M D+L SSHP+S S + + QI E+FD++SY Sbjct: 371 EYFSLEKIFKELSSYEDF-LDARFKTMKKDSLNSSHPIS---SSVQSSEQIEEMFDSLSY 426 Query: 478 SKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVR 537 KG+S+L ML ++LSEDVF+ + YLH +Y + +LWD E N V+ Sbjct: 427 FKGSSLLLMLKTYLSEDVFQHAVVLYLHNHSYASIQSDDLWDSFNEVTNQ-----TLDVK 481 Query: 538 DIMNRWTLQMGFPVITVDTSTGT--LSQEHFLLDPDSNVTRPSEFNYVWIVPITSIRDGR 595 +M WTLQ GFP++TV + QE F L+ + +PS+ +Y+W +P++ + +GR Sbjct: 482 RMMKTWTLQKGFPLVTVQKKGKELFIQQERFFLNMKPEI-QPSDTSYLWHIPLSYVTEGR 540 Query: 596 QQQDYWLID--VRAQNDLFSTSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQLQRDHSAI 653 Y + + + T WV +N+N+ GYY V+Y +++W + QL+ + + Sbjct: 541 NYSKYQSVSLLDKKSGVINLTEEVLWVKVNINMNGYYIVHYADDDWEALIHQLKINPYVL 600 Query: 654 PVINRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQYMPWEAALSSLSYFKLMFDRSE 713 +RA +IN+ F LA KVP+ A + +L E P AL L+++ E Sbjct: 601 SDKDRANLINNIFELAGLGKVPLKRAFDLINYLGNENHTAPITEALFQTD---LIYNLLE 657 Query: 714 VYGPMKNYLKKQVTPLFIHFRN--NTNNWREIPENLMDQYSEVNAISTACSNGVPECEEM 771 G M + + VT +F +N W + + + AC++ + C Sbjct: 658 KLGYM-DLASRLVTRVFKLLQNQIQQQTWTD-EGTPSMRELRSALLEFACTHNLGNCSTT 715 Query: 772 VSGLFKQWMENPNNNPIHPNLRSTVYCNAIAQGGEEEWDFAWEQFRNATLVNEADKLRAA 831 LF WM + + ++ +TV+ + ++ W F ++ + E +K+ A Sbjct: 716 AMKLFDDWMASNGTQSLPTDVMTTVF--KVGAKTDKGWSFLLGKYISIGSEAEKNKILEA 773 Query: 832 LACSKELWILNRYLSYTLNPDLIRKQDATSTIISITNNVIGQGLVWDFVQSNWKKLFNDY 891 LA S+++ L + +LN D R Q + I ++ + G L WDFV+ NW KL + Sbjct: 774 LASSEDVRKLYWLMKSSLNGDNFRTQKLSFIIRTVGRHFPGHLLAWDFVKENWNKLVQKF 833 Query: 892 GGGSFSFSNLIQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTRALEQALEKTKANIKWV 951 GS++ N++ T FST+ L +++ F ++ E F R +++ALE + NI+W+ Sbjct: 834 PLGSYTIQNIVAGSTYLFSTKTHLSEVQAFFENQSEATF--RLRCVQEALEVIQLNIQWM 891 Query: 952 KENKEVVLQWF-TENSK 967 ++N + + W TE S+ Sbjct: 892 EKNLKSLTWWLRTETSQ 908 >4KXA-A nrPDB Length = 888 Score = 973 bits (2516), Expect = 0.0, Method: Composition-based stats. Identities = 315/913 (34%), Positives = 492/913 (53%), Gaps = 57/913 (6%) Query: 64 TLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSSTVRFTCKEATDVIIIH 123 + D+S W +RLP+ + P Y + ++P L + + G+ ++ T + +H Sbjct: 6 SEDESGQWKNFRLPDFVNPVHYDLHVKPLLEED-----TYTGTVSISINLSAPTRYLWLH 60 Query: 124 SKKLNYT-LSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVVHLKGSLVK--------DS 174 ++ T L + R P D+ ++ EY + D Sbjct: 61 LRETRITRLPELKR-----------PSGDQVQVRRCFEYKKQEYVVVEAEEELTPSSGDG 109 Query: 175 QYEMDSEFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKAEFN 234 Y + EF G L L GFYR+ Y E K +A T + DARKSFPCFDEP KA + Sbjct: 110 LYLLTMEFAGWLNGSLVGFYRTTYTENGRVKSIAATDHEPTDARKSFPCFDEPNKKATYT 169 Query: 235 ITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQA 294 I++ HPK+ ALSNM + D W T F + MSTYL+ F V +FD V++ + Sbjct: 170 ISITHPKEYGALSNMPVAKEESV---DDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKRIS 226 Query: 295 SNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAM 354 ++G + I+ +P +YA N+T + ++F ++ Y LPK D+I +PDF GAM Sbjct: 227 NSGKPLTIYVQPEQ--KHTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAM 284 Query: 355 ENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFA 414 ENWGL+TYRE +LL+DP S+SSN++RV TV+AHEL HQWFGN+VT++WW DLWLNEGFA Sbjct: 285 ENWGLITYRETNLLYDPKESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFA 344 Query: 415 SYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDA 474 S+ E+LG ++AE W ++D M+L DV V D+L SSHP+ + TP +I+ +FD Sbjct: 345 SFFEFLGVNHAETDWQMRDQMLLEDVLPVQEDDSLMSSHPI---IVTVTTPDEITSVFDG 401 Query: 475 ISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPT 534 ISYSKG+S+LRML ++ + F++G YL + ++N + W L+EA Sbjct: 402 ISYSKGSSILRMLEDWIKPENFQKGCQMYLEKYQFKNAKTSDFWAALEEAS-------RL 454 Query: 535 TVRDIMNRWTLQMGFPVITVDTSTGTLSQEHFLLDPDSNVTRPS-EFNYVWIVPITSIRD 593 V+++M+ WT QMG+PV+ V+ ++Q+ FLLDP +N ++P + Y W +P+ D Sbjct: 455 PVKEVMDTWTRQMGYPVLNVN-GVKNITQKRFLLDPRANPSQPPSDLGYTWNIPVKWTED 513 Query: 594 GRQQQDYWLIDVRAQNDLFS--TSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQLQRDHS 651 + + L S SGN ++ +N + G+YRVNY+ W I T L +H Sbjct: 514 NITSSVLFNRSEKEGITLNSSNPSGNAFLKINPDHIGFYRVNYEVATWDSIATALSLNHK 573 Query: 652 AIPVINRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQYMPWEAALSSLSYFKLMF-D 710 +RA +I+DAF LA A + +ALN T +L E ++PW+ +S+++Y MF D Sbjct: 574 TFSSADRASLIDDAFALARAQLLDYKVALNLTKYLKREENFLPWQRVISAVTYIISMFED 633 Query: 711 RSEVYGPMKNYLKKQVTPLFIHFRNNTNNWREIPENLMDQYSEVNAISTACSNGVPECEE 770 E+Y ++ Y + QV P+ ++ W + +++ + + + AC G E Sbjct: 634 DKELYPMIEEYFQGQVKPI-----ADSLGWNDAGDHVT-KLLRSSVLGFACKMGDREALN 687 Query: 771 MVSGLFKQWMENPNNNPIHPNLRSTVYCNAIAQGGEE-EWDFAWEQFRNATLVNEADKLR 829 S LF+QW+ + NLR VY + G E W++ EQ++ +L E +KL Sbjct: 688 NASSLFEQWL--NGTVSLPVNLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLAQEKEKLL 745 Query: 830 AALACSKELWILNRYLSYTLNPDLIRKQDATSTIISITNNVIGQGLVWDFVQSNWKKLFN 889 LA K + +L+RYL + +LI+ QD + I I+ N G+ + W+++Q NW L N Sbjct: 746 YGLASVKNVTLLSRYLDLLKDTNLIKTQDVFTVIRYISYNSYGKNMAWNWIQLNWDYLVN 805 Query: 890 DYGGGSFSFSNLIQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTRALEQALEKTKANIK 949 Y + + ++ + F+TE +L Q+E F + G G R EQ LE K NI+ Sbjct: 806 RYTLNNRNLGRIV-TIAEPFNTELQLWQMESFFAKYPQAGAGEKPR--EQVLETVKNNIE 862 Query: 950 WVKENKEVVLQWF 962 W+K+++ + +WF Sbjct: 863 WLKQHRNTIREWF 875 >4WZ9-A nrPDB Length = 957 Score = 817 bits (2110), Expect = 0.0, Method: Composition-based stats. Identities = 288/916 (31%), Positives = 441/916 (48%), Gaps = 63/916 (6%) Query: 60 ASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSSTVRFTCKEATDV 119 A A +D+ RYRLP T P Y + LR + N+R F G+ ++ +ATD Sbjct: 37 APAQAVDE-----RYRLPTTSIPIHYDLHLRTEIHRNER---TFTGTVGIQLQVVQATDK 88 Query: 120 IIIHSKKLNYTLSQGHRVVLR-GVGGSQPPDIDKTELVEPTEYLVVHLKGSLVKDSQYEM 178 +++H++ L +S L GV G+ D + T + ++++ Y + Sbjct: 89 LVMHNRGL--VMSSAKVSSLPNGVTGAPTLIGDVQYSTDTTFEHITFTSPTILQPGTYLL 146 Query: 179 DSEFEGELADDLAGFYRSEYMEGN-VRKVVATTQMQAADARKSFPCFDEPAMKAEFNITL 237 + F+G LA + GFY S Y+ N R+ +ATTQ ++ AR +FPC+DEP +KA F +++ Sbjct: 147 EVAFQGRLATNDDGFYVSSYVADNGERRYLATTQFESTSARMAFPCYDEPGLKATFTVSI 206 Query: 238 IHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQASNG 297 H A+SNM P+ +T + D T F TP MSTYLLAF+VS+F A Sbjct: 207 THSLSYKAISNM-PQKTTTDIETD--MRTTFFEKTPAMSTYLLAFVVSDFQLRLSGAQR- 262 Query: 298 VLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYP--LPKSDQIGLPDFNAGAME 355 ++ RP+A +AL IL H PY +PK DQI +PDF AGAME Sbjct: 263 ----VYVRPNAF--NEATFALEAGVKILKVLDDHLGIPYDTYMPKLDQIAIPDFAAGAME 316 Query: 356 NWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFAS 415 NWGLVTYRE +LLF+P S+ K V T IAHE AHQWFGNLV+ EWW +WLNEGFA+ Sbjct: 317 NWGLVTYREQALLFNPAVSTYRGKTNVATTIAHEYAHQWFGNLVSPEWWEYIWLNEGFAT 376 Query: 416 YVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDAI 475 E+ D A P +L + M D AS+ P++ A+ TP +IS LFD + Sbjct: 377 LYEFYALDMAYPGQEYWELFNQQVIQYAMGQDGQASTRPMNWNAA---TPGEISALFDRV 433 Query: 476 SYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSI-QLPT 534 +Y K SVL M+ L +D +K GL +YL A Q + L+ LQ A+ + + Sbjct: 434 AYDKSGSVLNMMRHVLGDDNWKAGLKAYLTDRALQGAVDEQLYAGLQSAIEGKGVLPNGV 493 Query: 535 TVRDIMNRWTLQMGFPVITV----DTSTGTLSQEHFLLDPDSNVTRPSEFNYVWIVPITS 590 TV IM WT + G+PV+ V DT +SQE F D T +W++P Sbjct: 494 TVAQIMRTWTNEAGYPVLNVRRSYDTGDVIISQERFYNDRKVPNTN------IWMIPYNY 547 Query: 591 IRDGRQQ----QDYWLIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQL 646 + + D+ + +A + NEW++ N GYYRVNYDE NW I L Sbjct: 548 VHQAKADFNEFDDFQWLATKAARIETTVPANEWIVFNKQQVGYYRVNYDEHNWELITNAL 607 Query: 647 QRDHSAIPVINRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQYMPWEAALSSLSYFK 706 + ++I +NRAQ+I+DA+ LA + ++ + +AL +L ER+Y PW AA +L+YF Sbjct: 608 HENWASIHRLNRAQLIDDAYWLARSGRLDLRVALRFMTYLRNEREYAPWTAANVALTYFN 667 Query: 707 LMFDRSEVYGPMKNYLKKQVTPLFIHFRNNTNNWREIPENLMDQYSEVNAIST-ACSNGV 765 + Y ++ + ++ + + P++ + V IST ACS G Sbjct: 668 NRLRGTAEYHNFLIFVDALIEDIYSLLTIDAVS----PDDTLLHKYLVQTISTWACSMGY 723 Query: 766 PECEEMVSGLFKQWMENPNNNP-IHPNLRSTVYCNAIAQGGEEEWDFAWEQFRNATLVNE 824 +C + L K E P +HP++ S YC + E E+ + + + N+ + E Sbjct: 724 TDCLMKTAALLKA--EASGTGPAVHPDIASVTYCYGMRSALESEFQYLYRKMMNSKNLAE 781 Query: 825 ADKLRAALACSKELWILNRYLSYTLNPD-----LIRKQDATSTIISI-TNNVIGQGLVWD 878 L +L CS L +L+ L R + + +I + G + + Sbjct: 782 RTMLIDSLGCSNNKEFLKAFLTTALGSGTGVEINYRADERRRVVQAIYSGGRTGVDALIE 841 Query: 879 FVQSNWKKLFNDY--GGGSFSFSNLIQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTRA 936 F+ L N++ + + ++ + A+ R + E+ +L G ++ Sbjct: 842 FLMD--PALVNEFVSTLSTSTLNSALSAIASRTNNVEEMNKLNALITAL---GSRVNSQT 896 Query: 937 LEQALEKTKANIKWVK 952 +AN+ WV Sbjct: 897 AANLRTTAQANLDWVN 912 >3RJO-A nrPDB Length = 419 Score = 524 bits (1349), Expect = e-149, Method: Composition-based stats. Identities = 109/420 (25%), Positives = 199/420 (47%), Gaps = 20/420 (4%) Query: 548 GFPVITVDTSTGT--LSQEHFLLDPDSNVTRPSEFNYVWIVPITSIRDGRQQQDYWLIDV 605 GFP+IT+ + QEH++ D + Y+W VP+T I +L+ Sbjct: 1 GFPLITITVRGRNVHMKQEHYMKGSDG----APDTGYLWHVPLTFITSKSDMVHRFLLKT 56 Query: 606 RAQNDLFSTSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQLQRDHSAIPVINRAQIINDA 665 + + L EW+ N+ + GYY V+Y+++ W + L+ H+A+ +RA +IN+A Sbjct: 57 KT-DVLILPEEVEWIKFNVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNA 115 Query: 666 FNLASAHKVPVTLALNNTLFLIEERQYMPWEAALSSL-SYFKLM--FDRSEVYGPMKNYL 722 F L S K+ + AL+ +L+L E + MP L+ L +KLM D +EV K +L Sbjct: 116 FQLVSIGKLSIEKALDLSLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFL 175 Query: 723 KKQVTPLFIHFRNNTNNWREIPENLMDQYSEVNAISTACSNGVPECEEMVSGLFKQWMEN 782 + + L + W + ++ ++ + AC + C + G F++W E+ Sbjct: 176 IRLLRDLI-----DKQTWTD-EGSVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKES 229 Query: 783 PNNNPIHPNLRSTVYCNAIAQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWILN 842 N + ++ V+ A+ E WDF + +++ + E ++ AL ++ L Sbjct: 230 NGNLSLPVDVTLAVF--AVGAQSTEGWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQ 287 Query: 843 RYLSYTLNPDLIRKQDATSTIISITNNVIGQGLVWDFVQSNWKKLFNDYGGGSFSFSNLI 902 L + D I+ Q+ + I N +G L W F++ NW KL + GS S ++++ Sbjct: 288 WLLDESFKGDKIKTQEFPQILTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMV 347 Query: 903 QAVTRRFSTEYELQQLEQFKKDNEETGFGSGTRALEQALEKTKANIKWVKENKEVVLQWF 962 T +FST L++++ F +E GS R ++Q +E + NI W+ +N + + W Sbjct: 348 MGTTNQFSTRTRLEEVKGFFSSLKEN--GSQLRCVQQTIETIEENIGWMDKNFDKIRVWL 405 >1Z1W-A nrPDB Length = 780 Score = 524 bits (1348), Expect = e-149, Method: Composition-based stats. Identities = 198/737 (26%), Positives = 335/737 (45%), Gaps = 84/737 (11%) Query: 175 QYEMDSEFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKAEFN 234 +++ F G+++D L+G Y + G + TT +A DAR+ FPC D PA KA F Sbjct: 68 PQKIEISFAGKVSDSLSGIYYAGRENGMI-----TTHFEATDARRMFPCVDHPAYKAVFA 122 Query: 235 ITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQA 294 IT++ KD A+SNM PK E V EF TP+MSTYLL + +F Y ++ Sbjct: 123 ITVVIDKDYDAISNMPPK-----RIEVSERKVVEFQDTPRMSTYLLYVGIGKFRYEYEKY 177 Query: 295 SNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAM 354 + LI +++ Y L++ + F+ ++ PY LPK I +P+F AGAM Sbjct: 178 RDIDLI-----LASLKDIRSKYPLDMARKSVEFYENYFGIPYALPKMHLISVPEFGAGAM 232 Query: 355 ENWGLVTYRENSLLFDPLSSSSSNKER-VVTVIAHELAHQWFGNLVTIEWWNDLWLNEGF 413 ENWG +T+RE + D +S+ +R VIAHE+AHQWFG+LVT++WWNDLWLNE F Sbjct: 233 ENWGAITFRE--IYMDIAENSAVTVKRNSANVIAHEIAHQWFGDLVTMKWWNDLWLNESF 290 Query: 414 ASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELFD 473 A+++ Y D P W+ ++ + D+L ++HP+ ++ P +IS++FD Sbjct: 291 ATFMSYKTMDTLFPEWSFWGDFFVSRTSGALRSDSLKNTHPIEV---DVRDPDEISQIFD 347 Query: 474 AISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLP 533 ISY KGAS+LRM+ + + F++G++ YL+ + N +LW +++ Sbjct: 348 EISYGKGASILRMIEDYAGYEEFRKGISKYLNDHKFGNAEGSDLWTAIEDVSGK------ 401 Query: 534 TTVRDIMNRWTLQMGFPVITVDTSTG--TLSQEHFLLDPDSNVTRPSEFNYVWIVPITSI 591 V+ +M W G+PVI + + T+ Q FLL+ E W VP+ Sbjct: 402 -PVKRVMEYWIKNPGYPVIKLKRNGRKITMYQTRFLLN--------GEEEGRWPVPVNIK 452 Query: 592 RDGRQQQDYWLIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQLQRDHS 651 + + + L++ A + + +N + G+YRV YD+ + + + Sbjct: 453 K--KDGVERILLEDEAS-----IEADGLIKINADSAGFYRVLYDDATFSDVMGHYRD--- 502 Query: 652 AIPVINRAQIINDAFN-LASAHKVPVTLALNNTLFLIEERQYMPWEAALSSLSYFKLMFD 710 + ++R +++D F L S H P T F +E + A + + Y +++ Sbjct: 503 -LSPLDRIGLVDDLFAFLLSGHIDPETYRQRIRNFFDDEDHNV-ITAIVGQMEYLRML-- 558 Query: 711 RSEVYGPMKNYLKKQVTPLFIHFRNNTNNWREIPENLMDQYSEVNAISTACSNGVPECEE 770 + + + ENL V+ + E Sbjct: 559 ----THAFDDDARAFCRSRMQFLTG------KQDENLKIALGRVSRLYVMVDESYAE--- 605 Query: 771 MVSGLFKQWMENPNNNPIHPNLRSTV-YCNAIAQGGEEEWDFAWEQFRNATLVNEADKLR 829 +S LFK + P +RS++ A+ G + E+FR+ + ++ Sbjct: 606 EMSKLFKDFDSA------EPEMRSSIATAYALVTGDLKG---LLEKFRSVDRDEDRVRII 656 Query: 830 AALACSKELWILNRYLSYTLNPDLIRKQDATSTIISITNNVIGQGLVWDFVQSNWK---K 886 +A K L+ + I+KQD S S + G+ +F+ +N + Sbjct: 657 SAFGKLKSNTDLSTVYGMVEKTE-IKKQDMISFFSSALETLPGR----EFIFANLDRIIR 711 Query: 887 LFNDYGGGSFSFSNLIQ 903 L Y G+ + S ++ Sbjct: 712 LVIRYFTGNRTASRTVE 728 >5DLL-A nrPDB Length = 867 Score = 388 bits (997), Expect = e-108, Method: Composition-based stats. Identities = 108/471 (22%), Positives = 190/471 (40%), Gaps = 36/471 (7%) Query: 128 NYTLSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLV---VHLKGSLVKDSQYEMDSEFEG 184 N + + +VL GV + + P E+ V + ++ + + E Sbjct: 53 NRENRENNTLVLDGVELKLLSIKLNNKHLSPAEFAVNENQLIINNVPEKFVLQTVVEINP 112 Query: 185 ELADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKD-- 242 L G Y+S V +TQ +A RK D P + A F + +I K Sbjct: 113 SANTSLEGLYKSG--------DVFSTQCEATGFRKITYYLDRPDVMAAFTVKIIADKKKY 164 Query: 243 LTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEK----QASNGV 298 LSN K S + ++ ++ V + K YL A + + ++ ++ V Sbjct: 165 PIILSNG-DKIDSGDISDNQHFAV--WKDPFKKPCYLFALVAGDLASIKDTYITKSQRKV 221 Query: 299 LIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWG 358 + I+A I H YA+ + + + Y L + +PDFNAGAMEN G Sbjct: 222 SLEIYAFKQDIDKCH--YAMQAVKDSMKWDEDRFGLEYDLDTFMIVAVPDFNAGAMENKG 279 Query: 359 LVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVE 418 L + ++ +++ + E V +V+ HE H W G+ VT W L L EG + + Sbjct: 280 LNIFNTKYIMASNKTATDKDFELVQSVVGHEYFHNWTGDRVTCRDWFQLSLKEGLTVFRD 339 Query: 419 YLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYS 478 N +D+ ++DV + + + P+S P + +++ + Y+ Sbjct: 340 QEFTS----DLNSRDVKRIDDVRIIRSAQFAEDASPMSHPIR-PESYIEMNNFYTVTVYN 394 Query: 479 KGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVRD 538 KGA ++RM+ + L E+ F++G+ Y Q + + + +A NNR L Sbjct: 395 KGAEIIRMIHTLLGEEGFQKGMKLYFERHDGQAVTCDDFVNAMADA-NNRDFSL------ 447 Query: 539 IMNRWTLQMGFPVITVDTSTGTLSQEHFL-LDPDSNVTRPSEFNYVWIVPI 588 RW Q G P I V + SQ + L L+ + T + +P+ Sbjct: 448 -FKRWYAQSGTPNIKVSENYDASSQTYSLTLEQTTLPTADQKEKQALHIPV 497 >5Y1X-A nrPDB Length = 914 Score = 376 bits (964), Expect = e-104, Method: Composition-based stats. Identities = 149/798 (18%), Positives = 285/798 (35%), Gaps = 103/798 (12%) Query: 134 GHRVVLRGVG-GSQPPDIDKTELVEPTEYL----VVHLKGSLVKDSQYEMDSE--FEGEL 186 G +V GVG I+ +LVE EY + + V S++ SE E Sbjct: 70 GEDLVFDGVGLKINEISINNKKLVEGEEYTYDNEFLTIFSKFVPKSKFAFSSEVIIHPET 129 Query: 187 ADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKD--LT 244 L G Y+S K + +Q +A R+ D P M A++++T+ K+ Sbjct: 130 NYALTGLYKS--------KNIIVSQCEATGFRRITFFIDRPDMMAKYDVTVTADKEKYPV 181 Query: 245 ALSNM-------LPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFD-----YVEK 292 LSN +P G DP+ YL A + + Y+ K Sbjct: 182 LLSNGDKVNEFEIPGGRHGARFNDPHLK----------PCYLFAVVAGDLKHLSATYITK 231 Query: 293 QASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAG 352 V + +++ ++ +AL + F ++ Y L + + + + DFN G Sbjct: 232 YTKKKVELYVFSEEKYVSKLQ--WALECLKKSMAFDEDYFGLEYDLSRLNLVAVSDFNVG 289 Query: 353 AMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEG 412 AMEN GL + NSLL +S + R++TV+ HE H + GN VT+ W L L EG Sbjct: 290 AMENKGLNIFNANSLLASKKNSIDFSYARILTVVGHEYFHNYTGNRVTLRDWFQLTLKEG 349 Query: 413 FASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELF 472 + E L ++ T + L+ V + +V L S PLS P + + + Sbjct: 350 LTVHRENLFSEEMTKTVTTR----LSHVDLLRSVQFLEDSSPLSHPIR-PESYVSMENFY 404 Query: 473 DAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQL 532 Y KG+ V+RM + L E+ +K+G Y+ + +++A + Sbjct: 405 TTTVYDKGSEVMRMYLTILGEEYYKKGFDIYIKKNDGNTATCEDFNYAMEQAYKMKKADN 464 Query: 533 PTTVRDIMNRWTLQMGFPVITVDTSTGTLSQEHFL-LDPDSNVTRPSEFNYVWIVPIT-- 589 + + W Q G P ++ + +++ + ++ + + +PI+ Sbjct: 465 SANLNQYL-LWFSQSGTPHVSFKYNYDAEKKQYSIHVNQYTKPDENQKEKKPLFIPISVG 523 Query: 590 --SIRDGRQQQDYWLIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYDEENW--RKIQTQ 645 + +G++ +++ ++D F + + G+ Y E+N + Sbjct: 524 LINPENGKEMISQTTLELTKESDTFVFNNIAVKPIPSLFRGFSAPVYIEDNLTDEERILL 583 Query: 646 LQRDHSAIPVINRAQII--------NDAF------NLASAHKVPVTLAL-NNTLFLIEER 690 L+ D A N I + F L S + PV + +L+E+ Sbjct: 584 LKYDSDAFVRYNSCTNIYMKQILMNYNEFLKAKNEKLESFNLTPVNAQFIDAIKYLLEDP 643 Query: 691 QYMPWEAA-LSSLSYFKLMFD-----RSEVYGPMKNYLKKQVTP--------LFIHFR-- 734 + + SL + + + ++V K Y+ KQ+ +F Sbjct: 644 HADAGFKSYIVSLPQDRYIINFVSNLDTDVLADTKEYIYKQIGDKLNDVYYKMFKSLEAK 703 Query: 735 NNTNNWREIPENL-----MDQYSEVNAISTACSNGVPECEEMV-----SGLFKQWMENPN 784 + + ++ + +S P + S W+ Sbjct: 704 ADDLTYFNDESHVDFDQMNMRTLRNTLLSLLSKAQYPNILNEIIEHSKSPYPSNWL-TSL 762 Query: 785 NNPIHPNLRSTVYCNAIAQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWILNRY 844 + + + +Y ++E +++ ++ + L + N Sbjct: 763 SVSAYFDKYFELYDKTYKLSKDDE--LLLQEWLKTVSRSDRKDIYEIL-----KKLENEV 815 Query: 845 LSYTLNPDLIRKQDATST 862 L + NP+ IR T Sbjct: 816 LKDSKNPNDIRAVYLPFT 833 >4QHP-A nrPDB Length = 870 Score = 357 bits (916), Expect = 1e-98, Method: Composition-based stats. Identities = 94/448 (20%), Positives = 165/448 (36%), Gaps = 36/448 (8%) Query: 121 IIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVVHLKGSLVKDSQYEMDS 180 ++ S+ G +VL G I+ E + + G + E+++ Sbjct: 36 VVKSRLTVEPQRVGEPLVLDGSAKLLSVKINGAAADYVLEGETLTIAGVPSERFTVEVET 95 Query: 181 EFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHP 240 E L G Y S TQ + RK D P + ++F T++ Sbjct: 96 EILPAENKSLMGLYASGGN--------LFTQCEPEGFRKITFYIDRPDVMSKFTTTIVAD 147 Query: 241 KD--LTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEF----DYVEKQA 294 K LSN K + +W ++ +YL A + + DY + Sbjct: 148 KKRYPVLLSNG-NKIDGGEFSDGRHW--VKWEDPFSKPSYLFALVAGDLAVTEDYFTTMS 204 Query: 295 SNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAM 354 V I + + +A+ + + + Y L + + DFN GAM Sbjct: 205 GRNVKIEFYTTEA--DKPKVGFAVESLKNAMKWDETRFGLEYDLDIFMVVAVGDFNMGAM 262 Query: 355 ENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFA 414 EN GL + +L D +++ ++ E + +V+ HE H W GN VT W L L EG Sbjct: 263 ENKGLNIFNTKFVLADSRTATDTDFEGIESVVGHEYFHNWTGNRVTCRDWFQLSLKEGLT 322 Query: 415 SYV--EYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELF 472 + E+ G + ++++ +L DA ++HP+ + +++ + Sbjct: 323 VFRDQEFSGDRASRAVRRIENIRLLR--QHQFPEDAGPTAHPVRPA-----SYEEMNNFY 375 Query: 473 DAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQL 532 Y KGA V+RM + L E+ F++G+ Y F + + D + I L Sbjct: 376 TMTVYEKGAEVVRMYHTLLGEEGFQKGMKLY---FQRHDGQAVTCDDFRAAMADANGINL 432 Query: 533 PTTVRDIMNRWTLQMGFPVITVDTSTGT 560 D W Q G PV+ + Sbjct: 433 -----DQFALWYSQAGTPVLEAEGRLKN 455 >4Q4I-A nrPDB Length = 891 Score = 352 bits (902), Expect = 5e-97, Method: Composition-based stats. Identities = 88/440 (20%), Positives = 159/440 (36%), Gaps = 41/440 (9%) Query: 160 EYLVVHLKGSLVKDSQYEMDSEFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAADARK 219 E + +L + ++ +E L G Y+S TQ +A R Sbjct: 97 EEEGALVISNLPERFTLKIINEISPAANTALEGLYQSG--------DALCTQCEAEGFRH 148 Query: 220 SFPCFDEPAMKAEFNITLIHPK-DLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTY 278 D P + A F +I K L + + L +W ++ Y Sbjct: 149 ITYYLDRPDVLARFTTKIIADKIKYPFLLSNGNRVAQGELENGRHW--VQWQDPFPKPCY 206 Query: 279 LLAFIVSEFDYV----EKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDT 334 L A + +FD + ++ V + ++ + +A+ + + + Sbjct: 207 LFALVAGDFDVLRDTFTTRSGREVALELYVDRGNLD--RAPWAMTSLKNSMKWDEERFGL 264 Query: 335 PYPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQW 394 Y L + + FN GAMEN GL + +L +++ + + VI HE H W Sbjct: 265 EYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTATDKDYLDIERVIGHEYFHNW 324 Query: 395 FGNLVTIEWWNDLWLNEGFASYVEY-----LGADYAEPTWNLKDLMVLNDVYRVMAVDAL 449 GN VT W L L EG + + LG+ N++ + L A DA Sbjct: 325 TGNRVTCRDWFQLSLKEGLTVFRDQEFSSDLGSRAVNRINNVRTMRGLQ-----FAEDAS 379 Query: 450 ASSHPLSTPASEINTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAY 509 +HP+ + +++ + Y KGA V+RM+ + L E+ F++G+ Y Sbjct: 380 PMAHPIRP-----DMVIEMNNFYTLTVYEKGAEVIRMIHTLLGEENFQKGMQLYFERH-- 432 Query: 510 QNTIYLNLWDHLQEAVNNRSIQLPTTVRDIMNRWTLQMGFPVITVDTSTGTLSQEHFLLD 569 + D +Q + ++ L RW Q G P++TV ++++ L Sbjct: 433 -DGSAATCDDFVQAMEDASNVDLSH-----FRRWYSQSGTPIVTVKDDYNPETEQYTLTI 486 Query: 570 PDSNVTRPSE-FNYVWIVPI 588 P + +P Sbjct: 487 SQRTPATPDQAEKQPLHIPF 506 >5FWQ-A nrPDB Length = 633 Score = 336 bits (862), Expect = 3e-92, Method: Composition-based stats. Identities = 109/472 (23%), Positives = 185/472 (39%), Gaps = 40/472 (8%) Query: 87 VTLRPYLTPNDRGLYVFKGSSTVRFTCKEAT-DVIIIHSKKLNYTLSQGHRVVLRGVGGS 145 + LR D G++ + +E +++ +K L +VV+ G Sbjct: 36 LHLR---CSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTI-----EKVVINGQEVK 87 Query: 146 QPPDIDKTELVEPTEYLVVHLKGSLVKDSQYEMDSEFEGELADDLAGFYRSEYMEGNVRK 205 ++ P E + +L K+ + ++ FE + E G Sbjct: 88 YALGERQSYKGSPMEISLP---IALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHP 144 Query: 206 VVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWN 265 + +Q QA R PC D P++K + + PK+L AL + + G TP PEDP+ Sbjct: 145 YLF-SQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDG-ETPDPEDPSRK 202 Query: 266 VTEFHTTPKMSTYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPIL 325 + +F + YL+A +V + G +W+ + Y + T +L Sbjct: 203 IYKFIQKVPIPCYLIALVVGALESR----QIGPRTLVWSEKEQVEK--SAYEFSETESML 256 Query: 326 NFFAGHYDTPYPLPKSDQIGLP-DFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVT 384 PY + D + LP F G MEN L T+ +LL + + Sbjct: 257 KIAED-LGGPYVWGQYDLLVLPPSFPYGGMENPCL-TFVTPTLLA--------GDKSLSN 306 Query: 385 VIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVE--YLGADYAEPTWNLKDLMVLNDVYR 442 VIAHE++H W GNLVT + W+ WLNEG Y+E G + E + L ++ Sbjct: 307 VIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQN 366 Query: 443 VMAVDALASSHPLSTPASEINTPAQISELFDAISYSKGASVLRMLSSFL-SEDVFKQGLA 501 +V +HP + ++ T + ++ Y KG ++L L L ++F L Sbjct: 367 --SVKTFGETHPFTKLVVDL-TDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLK 423 Query: 502 SYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVRDIMNRWTLQMGFPVIT 553 +Y+ F+Y++ + D L ++ L N W G P I Sbjct: 424 AYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQV---DWNAWLYSPGLPPIK 472 >5ZI5-A nrPDB Length = 921 Score = 321 bits (821), Expect = 1e-87, Method: Composition-based stats. Identities = 95/447 (21%), Positives = 179/447 (40%), Gaps = 48/447 (10%) Query: 132 SQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVV---HLKGSLVKDSQYEMDSEFEGELAD 188 S + +VL G + L++ EY + + ++ +++ + ++ Sbjct: 79 SHSNDLVLDGENMTLVSLQMNDNLLKENEYELTKDSLIIKNIPQNTPFTIEMTSLLGENT 138 Query: 189 DLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKD--LTAL 246 DL G Y +E VA + ++ R+ F D P A + T+I ++ L Sbjct: 139 DLFGLYETEG--------VALVKAESEGLRRVFYLPDRPDNLATYKTTIIANQEDYPVLL 190 Query: 247 SN-MLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFD----YVEKQASNGVLIR 301 SN +L + PL +VT PK +YL A + Y + ++ + I Sbjct: 191 SNGVLIEKKELPLGL---HSVTWLDDVPK-PSYLFALVAGNLQRSVTYYQTKSGRELPIE 246 Query: 302 IWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWGLVT 361 + PSA + D+A V + + ++ L + G+ + +GA E GL Sbjct: 247 FYVPPSATSKC--DFAKEVLKEAMAWDERTFNLECALRQHMVAGVDKYASGASEPTGLNL 304 Query: 362 YRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEYLG 421 + +L P + + RV+ V+AHE H W G+ VTI W +L L EG ++ Sbjct: 305 FNTENLFASPETKTDLGILRVLEVVAHEFFHYWSGDRVTIRDWFNLPLKEGLTTFR---A 361 Query: 422 ADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKGA 481 A + E + D+ R++ L P + + + + L+ A +Y K A Sbjct: 362 AMFREELFG-------TDLIRLLDGKNLDERAPRQSAYTAVRS------LYTAAAYEKSA 408 Query: 482 SVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVRDIMN 541 + RM+ F+ ++ F + +A + F + + L D ++ N+ L Sbjct: 409 DIFRMMMLFIGKEPFIEAVAKF---FKDNDGGAVTLEDFIESISNSSGKDL-----RSFL 460 Query: 542 RWTLQMGFPVITVDTSTGTLSQEHFLL 568 W + G P + V ++++FL Sbjct: 461 SWFTESGIPELIVTDELNPDTKQYFLK 487 >4GAA-A nrPDB Length = 609 Score = 309 bits (790), Expect = 6e-84, Method: Composition-based stats. Identities = 103/484 (21%), Positives = 180/484 (37%), Gaps = 49/484 (10%) Query: 78 NTLKPDSYRV-TLRPYLTPNDRGLYVFKGSSTVRFTCKEATDVIIIHSKKLNY--TLSQG 134 + P+ + + + L + + +S + +++ +I+ +K L G Sbjct: 6 SFASPEKFNIKHMHLKLHVDFTSRAIAASTSLTVRSLQDSLASLILDTKDLTIKKVAVNG 65 Query: 135 HRVVLRGVG----GSQPPDIDKTELVEPTEYLVVHLKGSLVKDSQYEMDSEFEGELADDL 190 P +I + + ++V + S L Sbjct: 66 KDATFALGTTHSFKGTPLEITLPFSLTRGQEVIVEIDSVTSPKSSAL------QWLN--- 116 Query: 191 AGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTALSNML 250 E G + + +Q QA R PC D P++K + + PK+L AL + L Sbjct: 117 -----KEQTAGKIHPYLF-SQCQATHCRSIIPCQDTPSVKFTYYSQVSVPKELMALMSAL 170 Query: 251 PKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIA 310 G + D N + F + +YL+A +V + G IW + Sbjct: 171 RDGELSE-QSDSNRKIYRFKQNVPIPSYLIALVVGALE----GRKVGPRTTIWTEKELLE 225 Query: 311 AGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLP-DFNAGAMENWGLVTYRENSLLF 369 ++A T +L + PY + D + LP F G MEN L T+ ++L Sbjct: 226 PSVYEFA--ETEKMLKYAED-LAGPYVWGQYDLLILPPSFPYGGMENPCL-TFVTPTVLA 281 Query: 370 DPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEYL--GADYAEP 427 + +VIAHE++H W GNLVT E W + WLNEG Y+E G Y E Sbjct: 282 --------GDRSLASVIAHEISHSWTGNLVTNETWENFWLNEGHTVYLERRIDGRLYGEE 333 Query: 428 TWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKGASVLRML 487 K L ++ +V+ +++PL+ ++ + F ++ Y KG ++L L Sbjct: 334 FRQFKALGGWKELQN--SVNTFGATNPLTNLVPNLHE-VDVDAAFSSVPYEKGFALLFYL 390 Query: 488 SSFL-SEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVRDIMNRWTLQ 546 L ++F L SY+ FA+++ L ++ L + W Sbjct: 391 EQLLGGPEIFLGFLKSYIQMFAFKSVTTEEWKKFLYSYFKDKVDILD---KVDWKGWMHT 447 Query: 547 MGFP 550 G P Sbjct: 448 PGMP 451 >2XPY-A nrPDB Length = 632 Score = 294 bits (751), Expect = 2e-79, Method: Composition-based stats. Identities = 104/469 (22%), Positives = 177/469 (37%), Gaps = 71/469 (15%) Query: 108 TVRFTCKEATDVIIIHSKKLNYTLSQGHRVVLR-GVGGSQPPDIDKTELVEPTEYLVVHL 166 +V F + + KKL+ ++ + L Q ID ++ E L Sbjct: 38 SVSFEKSAISGSVTFQLKKLHEGKNKSDELHLDTSYLDVQEVHIDGSKADFQIEQRKEPL 97 Query: 167 KGSLVKDS-----QYEMDSEFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSF 221 LV ++ + ++ +F D + K +Q++A AR F Sbjct: 98 GSRLVINNASCNDNFTLNIQF--RTTDKCTALQWLNSKQTKGGKPYVFSQLEAIHARSLF 155 Query: 222 PCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPED--PNWNVTEFHTTPKMSTYL 279 PCFD P++K+ F ++ P LP S ED + N+ F + YL Sbjct: 156 PCFDTPSVKSTFTASIESP---------LPVVFSGIRIEDTSKDTNIYRFEQKVPIPAYL 206 Query: 280 LAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTG-------PILNFFAGHY 332 + + A G ++ P + ++ +V I + G Y Sbjct: 207 IGIASGDL----SSAPIGPRSTVYTEPFRLKDCQWEFENDVEKFIQTAEKIIFEYEWGTY 262 Query: 333 DTPYPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAH 392 D + + + G ME+ + T+ +L+ S+ VIAHELAH Sbjct: 263 DI--------LVNVDSYPYGGMESPNM-TFATPTLIAHDRSNID--------VIAHELAH 305 Query: 393 QWFGNLVTIEWWNDLWLNEGFASYVE--YLGADYAEPTWNLKDLMVLNDVYRVMAVDALA 450 W GNLVT WN WLNEG+ Y+E +GA + EPT + L+ +D+ ++D++ Sbjct: 306 SWSGNLVTNCSWNHFWLNEGWTVYLERRIIGAIHGEPTRHFSALIGWSDLQN--SIDSMK 363 Query: 451 SSHPLSTPASEINTPAQISELFDAISYSKGASVLRMLSSFLS---------EDVFKQGLA 501 ST +N + F + Y KG ++L L + L FK+ Sbjct: 364 DPERFSTLVQNLNDNTDPDDAFSTVPYEKGFNLLFHLETILGGKAEFDPFIRHYFKKFAK 423 Query: 502 SYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVRDIMNRWTLQMGFP 550 L TF + +T+Y + +E +++ W + G P Sbjct: 424 KSLDTFQFLDTLYE-FYPEKKEILDSVD----------WETWLYKPGMP 461 >3CIA-A nrPDB Length = 605 Score = 286 bits (732), Expect = 3e-77, Method: Composition-based stats. Identities = 99/444 (22%), Positives = 167/444 (37%), Gaps = 47/444 (10%) Query: 196 SEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPS 255 S K +Q QA AR P D P+++ + + KDL A+ + P Sbjct: 129 SAEQTAGKEKPFLFSQNQAIHARSWIPIQDTPSVRVTYTARITTDKDLLAVMSA-NNEPG 187 Query: 256 TPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGD 315 T D F + YL+A V + ++ G+ + +A+A Sbjct: 188 TERDGD-----YFFSMPQAIPPYLIAIGVGDLEFKAMSHQTGIYAESYILDAAVAEFDDT 242 Query: 316 YALNVTGPIL--NFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDPLS 373 A+ + + G YD LP P F G MEN L ++ +++ Sbjct: 243 QAMIDKAEQMYGKYRWGRYDL-LMLP-------PSFPFGGMENPRL-SFITPTVVA---- 289 Query: 374 SSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEYLGADYAEPTWNL-- 431 + +V +IAHELAH W GNLVT E W DLWLNEGF SYVE + T Sbjct: 290 ----GDKSLVNLIAHELAHSWSGNLVTNESWRDLWLNEGFTSYVENRIMEAVFGTDRAVM 345 Query: 432 -KDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKGASVLRMLSSF 490 + L + ++ +DA + + + F + Y KG L L Sbjct: 346 EQALGAQDLNAEILELDASDTQLYIDLKGR------DPDDAFSGVPYVKGQLFLMYLEEK 399 Query: 491 LSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVRD-IMNRWTLQMGF 549 + F + Y + A+Q+ N +L+ N + + P V D +N W + G Sbjct: 400 FGRERFDAFVLEYFDSHAFQSLGTDNFVKYLKA---NLTDKYPNIVSDNEINEWIFKAGL 456 Query: 550 PVITVDTSTGT----LSQEHFLLDPDSNVTRPSEFNYVWIVPITSIRD-GRQQQDYWLID 604 P ++ Q + L+ + + + + + I + +++ Sbjct: 457 PSYAPQPTSNAFKVIDKQINQLVTDELTLEQLPTAQWTLHEWLHFINNLPVDLDHQRMVN 516 Query: 605 VRAQNDLFSTS----GNEWVLLNL 624 + DL ++S + W LL++ Sbjct: 517 LDKAFDLTNSSNAEIAHAWYLLSV 540 >4FGM-A nrPDB Length = 597 Score = 44.8 bits (104), Expect = 2e-04, Method: Composition-based stats. Identities = 39/300 (13%), Positives = 94/300 (31%), Gaps = 34/300 (11%) Query: 350 NAGAME--NWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIE----- 402 G +E N + L+ + N + +++ HE H W N+ T++ Sbjct: 233 GFGGLEHRNSTALLCSRKDLISAHQYEMNDNYQTFLSLCCHEYFHSW--NIKTLKPKAFL 290 Query: 403 --------WWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMA------VDA 448 + LW EG SY + + + L +L D + + Sbjct: 291 PYQLEKESYTEQLWFYEGMTSYFDDYLLHTSGIIDEKRYLKLLGDTLSRVERGAGQYQQS 350 Query: 449 LASSHPLSTPASEINTPAQISELFDAISYSKGASV---LRMLSSFLSEDVFKQG--LASY 503 + S L+ + + Y+KGA + L ++ S+ + Sbjct: 351 VTESSFLAWTKFYQQNENAPNSIVSY--YAKGALIALSLDLMLRLQSDHKLTLARVMKEL 408 Query: 504 LHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVRDIMNRWTLQMGFPVITVDTSTGTLSQ 563 H F + + + I + ++D + + ++ + + G + Q Sbjct: 409 WHEFGKTSIGTAD-DTVINWLNQYPGIDISDFLKDAL---YNKESLSLVELLQNFGVMVQ 464 Query: 564 EHFLLDPDSNVTRPSEFNYVWIVPITSIRDGRQQQDYWLIDVRAQNDLFSTSGNEWVLLN 623 + +D +S + SE + + + ++G++ + ++ Sbjct: 465 KQVPVDDNSVGGKASEQPARVNFGAKYKASPQGLDVLNVYHDESAYHAGLSAGDKIIAID 524 >3ZUK-A nrPDB Length = 699 Score = 38.3 bits (87), Expect = 0.015, Method: Composition-based stats. Identities = 24/105 (22%), Positives = 37/105 (35%), Gaps = 16/105 (15%) Query: 356 NWGLVTYRENSL-----LFDPLSSSSSNKERVVTVIAHELAHQW---------FGNLVTI 401 N G+ + FDP + ++N + VI HE+ H + GNLV Sbjct: 492 NPGMNEIVFPAAILQPPFFDPQADEAANYGGIGAVIGHEIGHGFDDQGAKYDGDGNLV-- 549 Query: 402 EWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAV 446 +WW D E A + +A +L D V + Sbjct: 550 DWWTDDDRTEFAARTKALIEQYHAYTPRDLVDHPGPPHVQGAFTI 594 >4RCO-A nrPDB Length = 295 Score = 36.8 bits (83), Expect = 0.048, Method: Composition-based stats. Identities = 20/93 (21%), Positives = 38/93 (40%), Gaps = 4/93 (4%) Query: 32 VYSQEKNKNANSSPVAS-TTPSASATTNPASATTLDQSKAWNRYRLPNTLKPDSYRV--- 87 V + ++ NA + P TTP ++ T P +T D ++ ++P + P + Sbjct: 54 VEAPQQTANATTPPSTKVTTPPSTNTPQPMQSTKSDTPQSPTTKQVPTEINPKFKDLRAY 113 Query: 88 TLRPYLTPNDRGLYVFKGSSTVRFTCKEATDVI 120 +P L + + K +T+RF I Sbjct: 114 YTKPSLEFKNEIGIILKKWTTIRFMNVVPDYFI 146 >1BQB-A nrPDB Length = 301 Score = 35.2 bits (79), Expect = 0.13, Method: Composition-based stats. Identities = 41/271 (15%), Positives = 83/271 (30%), Gaps = 22/271 (8%) Query: 285 SEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNV---TGPILNFFAGHYDTP-YPLPK 340 + G I ++ +++ + Y Sbjct: 35 GKLSAYNFNDQTGQATLITNEDENFVKDDQRAGVDANYYAKQTYDYYKNTFGRESYDNHG 94 Query: 341 SDQIGLPDFN-AGAMENWGLVTY-RENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNL 398 S + L N G +N + + + D + +N V+AHE+ H Sbjct: 95 SPIVSLTHVNHYGGQDNRNNAAWIGDKMIYGDGDGRTFTNLSGANDVVAHEITHGVTQQT 154 Query: 399 VTIEWWNDL-WLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALAS-----S 452 +E+ + LNE F+ Y D E +D+ + + S Sbjct: 155 ANLEYKDQSGALNESFSDVFGYFVDD--EDFLMGEDVYTPGKEGDALRSMSNPEQFGQPS 212 Query: 453 HPLSTPASEINTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNT 512 H +E + + I +V++ + SE ++ + L YL + N+ Sbjct: 213 HMKDYVYTEKDNGGVHTN--SGIPNKAAYNVIQAIGKSKSEQIYYRALTEYLTS----NS 266 Query: 513 IYLNLWDHLQEAVNNRSIQLPTTVRDIMNRW 543 + +L D L +A + + T + W Sbjct: 267 NFKDLKDALYQA--AKDLYEQQTAEQVYEAW 295 >4XBH-A nrPDB Length = 696 Score = 34.8 bits (78), Expect = 0.16, Method: Composition-based stats. Identities = 24/133 (18%), Positives = 39/133 (29%), Gaps = 37/133 (27%) Query: 349 FNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAH---------QWFGNLV 399 F AG ++ F S+S N + VI HE+ H G+LV Sbjct: 501 FPAGILQPP----------FFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLV 550 Query: 400 TIEWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPA 459 +WW N ++ E + DL + ++T Sbjct: 551 --DWWTQQSAN----NFKEQSQCMVYQYGNFSWDLAGGQHLNG------------INTLG 592 Query: 460 SEINTPAQISELF 472 I I + + Sbjct: 593 ENIADNGGIGQAY 605 >3SQR-A nrPDB Length = 580 Score = 34.4 bits (77), Expect = 0.22, Method: Composition-based stats. Identities = 30/176 (17%), Positives = 61/176 (34%), Gaps = 14/176 (7%) Query: 28 ALSVVYSQEKNKNANSSPVASTTPSASATTNPASATTLDQSKAWNRYRL--------PNT 79 AL+ +++Q +A++ P +T + T + A + W Y + P Sbjct: 9 ALTALFAQ---ASASAIPAVRSTLTPRQNTTASCANSATSRSCWGEYSIDTNWYDVTPTG 65 Query: 80 LKPDSYRVTLRPYLTPN--DRGLYVFKGSSTVRFTCKEATDVIIIH-SKKLNYTLSQGHR 136 + + + +TP+ R F G+ + D +IIH + L + + H Sbjct: 66 VTREYWLSVENSTITPDGYTRSAMTFNGTVPGPAIIADWGDNLIIHVTNNLEHNGTSIHW 125 Query: 137 VVLRGVGGSQPPDIDKTELVEPTEYLVVHLKGSLVKDSQYEMDSEFEGELADDLAG 192 +R +G + + + K + + S F + D L G Sbjct: 126 HGIRQLGSLEYDGVPGVTQCPIAPGDTLTYKFQVTQYGTTWYHSHFSLQYGDGLFG 181 >4WNR-A nrPDB Length = 349 Score = 33.7 bits (75), Expect = 0.37, Method: Composition-based stats. Identities = 27/170 (15%), Positives = 53/170 (31%), Gaps = 9/170 (5%) Query: 801 IAQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIRKQDAT 860 + QG E ++ +NE L + + +L R L + + + Q Sbjct: 18 VKQGREAVINYFKSLEGEKKPLNEVKVLLVGDGEAGKTSLLKRLLGEGFDGNEHQTQGIN 77 Query: 861 STIISITNNVIGQGLV---WDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQQ 917 I + + WDF + + S L+ R EY L+ Sbjct: 78 --IKKWGFKDKDKEIKVNFWDFGGQEIMHATHQFFLSKRSLYILVLDSRRDEKAEYWLKH 135 Query: 918 LEQFKKDNEETGFGSGTRALEQALEKTKANIKWVKENKEVVLQWFTENSK 967 + F D+ + + N K+++E + +F + K Sbjct: 136 IRSFGGDSPVLVALNKIDEN----PSFELNRKFLQEKYPSIKGFFRISCK 181 >4CTH-A nrPDB Length = 709 Score = 33.7 bits (75), Expect = 0.39, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 33/104 (31%), Gaps = 25/104 (24%) Query: 349 FNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAH---------QWFGNLV 399 F AG ++ F S+S N + VI HE+ H G+LV Sbjct: 514 FPAGILQPP----------FFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLV 563 Query: 400 TIEWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRV 443 W W + +++ E + DL + + Sbjct: 564 ---DW---WTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGI 601 >3OSL-A nrPDB Length = 401 Score = 33.3 bits (74), Expect = 0.50, Method: Composition-based stats. Identities = 29/204 (14%), Positives = 72/204 (35%), Gaps = 15/204 (7%) Query: 634 YDEENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQYM 693 Y W+ + + + A +++ +A ++P + + N LI ++ Sbjct: 27 YKIVLWQPVAAEYIVKGYEVHFFVNASDVSNVKAHLNASRIPFRVLVENVEDLIRQQTSN 86 Query: 694 PWEAALSSLSYFKLMFDRSEVYGPMKNYLKKQ---VTPLFIHFRNNTNNWREIPENLMDQ 750 + +S SY++ +E+Y ++ ++ V + I + + +Q Sbjct: 87 DTISPRASSSYYEQYHSLNEIYSWIEVMTERYPDMVEKIHIGSSYEKYPLYVLKVSKKEQ 146 Query: 751 YSEVNAISTACSNGVPECEEMVSGLFKQWMENP-----NNNPIHPNLRSTVYCNAIAQGG 805 ++ NA+ C E F W +H NL + + Sbjct: 147 RAK-NAMWIDCGIHAREWISPA---FCLWFVGSVTYYYGKEKMHTNLLKHMDFYIMPVVN 202 Query: 806 EEEWDFAWEQ---FRNATLVNEAD 826 + +D+ W++ +R ++E + Sbjct: 203 VDGYDYTWKKDRMWRKNRSLHEKN 226 >3NIV-A nrPDB Length = 222 Score = 31.4 bits (69), Expect = 1.9, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 16/37 (43%) Query: 404 WNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDV 440 W WL GF ++ E LGA + + L DV Sbjct: 133 WYHHWLKTGFDAFEEKLGALERDKPVCFGSEVGLADV 169 >3MDV-A nrPDB Length = 456 Score = 31.0 bits (68), Expect = 2.9, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 21/41 (51%) Query: 462 INTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLAS 502 + +P + + + Y+K + + R L + E +F QGL S Sbjct: 39 VTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFGQGLVS 79 >4CDB-A nrPDB Length = 488 Score = 30.6 bits (67), Expect = 3.7, Method: Composition-based stats. Identities = 10/82 (12%), Positives = 34/82 (41%), Gaps = 5/82 (6%) Query: 586 VPITSIRDGRQQQDYWLIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQ 645 VPI + + + +I ++ ++ +N++ +G Y ++ +W ++ Sbjct: 345 VPIAYTTNFLKDNELAVIKNNSEYIETTSKAYTDGKINIDHSGGYVAQFNI-SWDEVNYD 403 Query: 646 LQRD----HSAIPVINRAQIIN 663 + + H N++++ + Sbjct: 404 PEGNEIVQHKNWSENNKSKLAH 425 >4AKR-A nrPDB Length = 281 Score = 30.2 bits (66), Expect = 4.1, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 32/79 (40%), Gaps = 3/79 (3%) Query: 623 NLNVTGYYRV--NYDEENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLAL 680 N+ G +V +Y E+ ++ T + + + P + +AF ++ + AL Sbjct: 181 NVTSNGKVQVNVHYFEDGNVQLNT-VTQKQTTSPSADAQSTAVNAFKAIGKAELNLHTAL 239 Query: 681 NNTLFLIEERQYMPWEAAL 699 +N + + + AL Sbjct: 240 DNNYSTMGDTTFKALRRAL 258 >5G5P-A nrPDB Length = 805 Score = 29.4 bits (64), Expect = 7.1, Method: Composition-based stats. Identities = 31/189 (16%), Positives = 64/189 (33%), Gaps = 19/189 (10%) Query: 33 YSQEKNKNANSSPVASTTPSASATTNPASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPY 92 Y+++ N+N++ P +T+P AT + +LP S+ ++ P Sbjct: 583 YNEKLNQNSSVKPQINTSPKRVAT------RPNHFPFSQESKQLPQ--ISQSHTLSTNPL 634 Query: 93 LTPNDRGLYVFKGSSTVRFTCKEATDVIIIHS-KKLNYTLSQGHRVVLRGVGGSQPPDID 151 LTP G + ++ + + S + S+ H + G Sbjct: 635 LTPQVHGDLSEQKQQQIKTVTDGGSPFVFDQSAQNSTVEASKAHMISTTSNGAYDEKLSS 694 Query: 152 KTELVEPTEYLVVHLKGSLVKDSQ-----YEMDSEFEGEL-----ADDLAGFYRSEYMEG 201 + E + E + + + +K Q + + +L + + E+ E Sbjct: 695 EQEEMRKKEEQRIEEEKTQLKKKQENADKQVITEQIANDLVKEVVNSSVISIVKREFSEA 754 Query: 202 NVRKVVATT 210 N RK T Sbjct: 755 NYRKDFIDT 763 >1WB0-A nrPDB Length = 445 Score = 29.4 bits (64), Expect = 8.2, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 27/74 (36%), Gaps = 3/74 (4%) Query: 494 DVFKQGLASYLHTFAYQNTI--YLNLWDHLQEAVNNRSIQLPTTVRDIMNRWTLQMGFPV 551 + FK + SYL + L+L D + N L T+R ++ L G P Sbjct: 317 ESFKTKV-SYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTLRQELSLPYLPSGTPE 375 Query: 552 ITVDTSTGTLSQEH 565 + V EH Sbjct: 376 LEVPKPGQPSEPEH 389 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.119 0.307 Lambda K H 0.267 0.0364 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 32,820,778 Number of Sequences: 36641 Number of extensions: 1229493 Number of successful extensions: 3807 Number of sequences better than 10.0: 35 Number of HSP's better than 10.0 without gapping: 41 Number of HSP's successfully gapped in prelim test: 20 Number of HSP's that attempted gapping in prelim test: 3534 Number of HSP's gapped (non-prelim): 69 length of query: 967 length of database: 10,336,785 effective HSP length: 106 effective length of query: 861 effective length of database: 6,452,839 effective search space: 5555894379 effective search space used: 5555894379 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 64 (29.4 bits)