BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P15121 (316 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3RX4-A nrPDB 659 0.0 1DLA-A nrPDB 547 e-156 1ZUA-X nrPDB 483 e-137 1C9W-A nrPDB 451 e-127 1FRB-A nrPDB 444 e-125 3O3R-A nrPDB 443 e-125 1Q5M-A nrPDB 342 1e-94 3G1R-A nrPDB 337 5e-93 2ALR-A nrPDB 326 8e-90 2FVL-A nrPDB 325 1e-89 4GAC-A nrPDB 324 3e-89 4JQA-A nrPDB 323 4e-89 1HQT-A nrPDB 322 1e-88 5JM5-A nrPDB 320 5e-88 4HBK-A nrPDB 317 3e-87 2HE8-A nrPDB 304 4e-83 1AFS-A nrPDB 303 9e-83 5UXF-A nrPDB 296 1e-80 3H7U-A nrPDB 256 1e-68 5JH1-A nrPDB 246 1e-65 5ZCM-A nrPDB 233 6e-62 3WCZ-A nrPDB 231 3e-61 1K8C-A nrPDB 227 6e-60 1QWK-A nrPDB 226 8e-60 3KRB-A nrPDB 226 1e-59 5Z6T-A nrPDB 225 2e-59 3H7R-A nrPDB 225 2e-59 4F40-A nrPDB 224 6e-59 1VBJ-A nrPDB 213 7e-56 2BGQ-A nrPDB 208 2e-54 4GIE-A nrPDB 206 1e-53 1VP5-A nrPDB 197 6e-51 3D3F-A nrPDB 195 2e-50 1MZR-A nrPDB 190 6e-49 4OTK-A nrPDB 177 4e-45 4MHB-A nrPDB 176 1e-44 4IJC-A nrPDB 171 4e-43 1A80-A nrPDB 171 5e-43 3UP8-A nrPDB 166 2e-41 4H8N-A nrPDB 140 7e-34 3WG6-A nrPDB 131 5e-31 1PZ1-A nrPDB 71 8e-13 1PYF-A nrPDB 59 4e-09 1LQA-A nrPDB 55 6e-08 1OG6-A nrPDB 47 1e-05 4R9O-A nrPDB 46 2e-05 3EB3-A nrPDB 45 3e-05 3N6Q-A nrPDB 44 1e-04 4UUD-B nrPDB 32 0.34 5NIK-J nrPDB 32 0.34 6DLV-b nrPDB 31 0.57 5N48-A nrPDB 30 1.2 5GZ9-A nrPDB 30 1.3 5FI5-A nrPDB 29 2.2 1M6J-A nrPDB 29 2.6 5ZF1-A nrPDB 29 2.8 >3RX4-A nrPDB Length = 336 Score = 659 bits (1701), Expect = 0.0, Method: Compositional matrix adjust. Identities = 316/316 (100%), Positives = 316/316 (100%) Query: 1 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ Sbjct: 21 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 80 Query: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK Sbjct: 81 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 140 Query: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP Sbjct: 141 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 200 Query: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK Sbjct: 201 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 260 Query: 241 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA 300 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA Sbjct: 261 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA 320 Query: 301 LLSCTSHKDYPFHEEF 316 LLSCTSHKDYPFHEEF Sbjct: 321 LLSCTSHKDYPFHEEF 336 >1DLA-A nrPDB Length = 314 Score = 547 bits (1410), Expect = e-156, Method: Compositional matrix adjust. Identities = 272/314 (86%), Positives = 294/314 (93%) Query: 3 SRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEK 62 S L+L GAKMPILGLGTWKSPPG+VTEAVKVAID+GYRHIDCAHVYQNENEVG+ +QEK Sbjct: 1 SHLVLYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLGLQEK 60 Query: 63 LREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEF 122 L+ QVVKRE+LFIVSKLWCT HEK LVKGACQ TL DLKLDYLDLYLIHWPTGFKPGK+ Sbjct: 61 LQGQVVKREDLFIVSKLWCTDHEKNLVKGACQTTLRDLKLDYLDLYLIHWPTGFKPGKDP 120 Query: 123 FPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAV 182 FPLD GNVVP +++ ++TW AMEELVDEGLVKAIG+SNFNHLQVE ILNKPGLKYKPAV Sbjct: 121 FPLDGDGNVVPDESDFVETWEAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAV 180 Query: 183 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHN 242 NQIE HPYLTQEKLI+YC+SKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK+N Sbjct: 181 NQIEVHPYLTQEKLIEYCKSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYN 240 Query: 243 KTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALL 302 KTTAQVLIRFPMQRNL+VIPKSVTPERIAENF+VFDFELS +DM TLLSYNRNWRVCAL+ Sbjct: 241 KTTAQVLIRFPMQRNLIVIPKSVTPERIAENFQVFDFELSPEDMNTLLSYNRNWRVCALM 300 Query: 303 SCTSHKDYPFHEEF 316 SC SHKDYPFHEE+ Sbjct: 301 SCASHKDYPFHEEY 314 >1ZUA-X nrPDB Length = 317 Score = 483 bits (1244), Expect = e-137, Method: Compositional matrix adjust. Identities = 223/316 (70%), Positives = 263/316 (83%) Query: 1 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60 MA+ + L+ AKMPI+GLGTWKSP G+V EAVKVAID GYRHIDCA+VYQNE+EVG AIQ Sbjct: 2 MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 61 Query: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120 EK++E+ VKRE+LFIVSKLW T+ E+ LV+ A +KTL DLKL YLD+YLIHWP GFK G Sbjct: 62 EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 121 Query: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180 + FP D+ GN + LD W AMEELVDEGLVKA+G+SNF+H Q+E +LNKPGLKYKP Sbjct: 122 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 181 Query: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240 NQ+ECHPYLTQEKLIQYC SKGI VTAYSPLGSPDRPWAKPEDPSLLEDP+IK IAAK Sbjct: 182 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 241 Query: 241 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA 300 H KT AQVLIRF +QRN++VIPKSVTP RI EN +VFDF+LS ++M T+LS+NRNWR C Sbjct: 242 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 301 Query: 301 LLSCTSHKDYPFHEEF 316 +L + +DYPF+ E+ Sbjct: 302 VLQSSHLEDYPFNAEY 317 >1C9W-A nrPDB Length = 315 Score = 451 bits (1161), Expect = e-127, Method: Compositional matrix adjust. Identities = 223/310 (71%), Positives = 260/310 (83%) Query: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66 L+ AKMPI+GLGTW+SPPGQV EAVKVAID GYRHIDCA+ Y NE+EVG AIQEK++E+ Sbjct: 6 LSTKAKMPIVGLGTWQSPPGQVKEAVKVAIDAGYRHIDCAYAYYNEHEVGEAIQEKIKEK 65 Query: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126 V+RE+LFIVSKLW T E+ L+K A QKTL+DLKLDYLDLYLIHWP G +PGKE FP D Sbjct: 66 AVRREDLFIVSKLWPTCFERKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKELFPKD 125 Query: 127 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 186 + GNV+ S LD W MEELVDEGLVKA+G+SNFNH Q+E ILNKPGLK+KP NQ+E Sbjct: 126 DQGNVLTSKITFLDAWEVMEELVDEGLVKALGVSNFNHFQIERILNKPGLKHKPVTNQVE 185 Query: 187 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTA 246 CHPYLTQEKLI+YC SKGI VTAYSPLGSP+RPWAKPEDPSLLEDP+IK IAAKH KT+A Sbjct: 186 CHPYLTQEKLIEYCHSKGITVTAYSPLGSPNRPWAKPEDPSLLEDPKIKEIAAKHKKTSA 245 Query: 247 QVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTS 306 QVLIRF +QRN+VVIPKSVTP RI ENF+VFDF+LS Q+M T+L +NRNWR C L + Sbjct: 246 QVLIRFHIQRNVVVIPKSVTPARIHENFQVFDFQLSDQEMATILGFNRNWRACLLPETVN 305 Query: 307 HKDYPFHEEF 316 ++YP+ E+ Sbjct: 306 MEEYPYDAEY 315 >1FRB-A nrPDB Length = 315 Score = 444 bits (1142), Expect = e-125, Method: Compositional matrix adjust. Identities = 221/315 (70%), Positives = 260/315 (82%) Query: 2 ASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQE 61 A+ + L+ AKMPI+GLGTWKSPP QV EAVK AID GYRHIDCA+ Y NENEVG AIQE Sbjct: 1 ATFVELSTKAKMPIVGLGTWKSPPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQE 60 Query: 62 KLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKE 121 K++E+ V+RE+LFIVSKLW T EK L+K A QKTL+DLKLDYLDLYLIHWP G +PGKE Sbjct: 61 KIKEKAVQREDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKE 120 Query: 122 FFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPA 181 FP D+ G ++ S T L+ W MEELVD+GLVKA+G+SNFNH Q+E +LNKPGLK+KP Sbjct: 121 LFPKDDQGRILTSKTTFLEAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPV 180 Query: 182 VNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKH 241 NQ+ECHPYLTQEKLIQYC SKGI VTAYSPLGSPDRP AKPEDPSLLEDP+IK IAAKH Sbjct: 181 TNQVECHPYLTQEKLIQYCHSKGISVTAYSPLGSPDRPSAKPEDPSLLEDPKIKEIAAKH 240 Query: 242 NKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCAL 301 KT+AQVLIRF +QRN+VVIPKSVTP RI EN +VFDF+LS ++M T+LS+NRNWR C L Sbjct: 241 EKTSAQVLIRFHIQRNVVVIPKSVTPSRIQENIQVFDFQLSDEEMATILSFNRNWRACLL 300 Query: 302 LSCTSHKDYPFHEEF 316 + ++YP+ E+ Sbjct: 301 PETVNMEEYPYDAEY 315 >3O3R-A nrPDB Length = 316 Score = 443 bits (1139), Expect = e-125, Method: Compositional matrix adjust. Identities = 218/316 (68%), Positives = 254/316 (80%) Query: 1 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60 M + + L AKMP++GLGTWKSPPGQV EAVK AID GYRH DCA+VYQNE+EVG AIQ Sbjct: 1 MTTFVKLRTKAKMPLVGLGTWKSPPGQVKEAVKAAIDAGYRHFDCAYVYQNESEVGEAIQ 60 Query: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120 EK++E+ V+RE+LFIVSKLW T+ EK L+K A QKTLSDLKLDYLDLYLIHWP G + GK Sbjct: 61 EKIKEKAVRREDLFIVSKLWSTFFEKSLMKEAFQKTLSDLKLDYLDLYLIHWPQGLQAGK 120 Query: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180 EF P D G V+ S + LD W MEELVD+GLVKA+G+SNFNH Q+E +LNKPGLK+KP Sbjct: 121 EFLPKDSQGKVLMSKSTFLDAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKP 180 Query: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240 NQ+ECHPYLTQEKLIQYC SKGI V AYSPLGSPDRP+AKPEDP +LE P+IK IAAK Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGIAVIAYSPLGSPDRPYAKPEDPVVLEIPKIKEIAAK 240 Query: 241 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA 300 H KT AQVLIRF +QRN+ VIPKSVT I EN +VFDF+LS +DM +LS NRNWR C Sbjct: 241 HKKTIAQVLIRFHVQRNVAVIPKSVTLSHIKENIQVFDFQLSEEDMAAILSLNRNWRACG 300 Query: 301 LLSCTSHKDYPFHEEF 316 L + +D+PFHEE+ Sbjct: 301 LFVTSDEEDFPFHEEY 316 >1Q5M-A nrPDB Length = 322 Score = 342 bits (877), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 161/317 (50%), Positives = 219/317 (69%), Gaps = 4/317 (1%) Query: 4 RLLLNNGAKMPILGLGTW---KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60 R+ L++G +P+LG GT+ + P + EA K+AID G+RHID A+ Y+NE EVG+AI+ Sbjct: 6 RVALSDGHFIPVLGFGTYAPEEVPKSKAMEATKIAIDAGFRHIDSAYFYKNEKEVGLAIR 65 Query: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120 K+ + VKRE++F SKLWCT+H LV+ + + +L +L+LDY+DLY+IH+PT KPG Sbjct: 66 SKIADGTVKREDIFYTSKLWCTFHRPELVRPSLEDSLKNLQLDYVDLYIIHFPTALKPGV 125 Query: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180 E P DE G + +I TW AME+ D GL K+IG+SNFN Q+EMILNKPGLKYKP Sbjct: 126 EIIPTDEHGKAIFDTVDICATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 185 Query: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP-WAKPEDPSLLEDPRIKAIAA 239 NQ+ECHPYL Q KL+++C+SKGIV+ AYS LGS P W P LLEDP I A+A Sbjct: 186 VCNQVECHPYLNQGKLLEFCKSKGIVLVAYSALGSHREPEWVDQSAPVLLEDPLIGALAK 245 Query: 240 KHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVC 299 KH +T A + +R+ +QR +VV+ KS T +RI EN +VF+F+L S+DM + S NRN+R Sbjct: 246 KHQQTPALIALRYQLQRGIVVLAKSFTEKRIKENIQVFEFQLPSEDMKVIDSLNRNFRYV 305 Query: 300 ALLSCTSHKDYPFHEEF 316 H +YPF +E+ Sbjct: 306 TADFAIGHPNYPFSDEY 322 >3G1R-A nrPDB Length = 346 Score = 337 bits (863), Expect = 5e-93, Method: Compositional matrix adjust. Identities = 159/320 (49%), Positives = 222/320 (69%), Gaps = 5/320 (1%) Query: 2 ASRLLLNNGAKMPILGLGTWK----SPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGV 57 + R+ L++G +PI+GLGT+ +P G +VKVAID GYRHID A++YQNE+EVG Sbjct: 27 SHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGE 86 Query: 58 AIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFK 117 AI+EK+ E V+RE++F KLW T H +V+ ++TL L+LDY+DLY+I P FK Sbjct: 87 AIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFK 146 Query: 118 PGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK 177 PG E +P DE+G + +N+ TW AME D GLVK++G+SNFN Q+E+ILNKPGLK Sbjct: 147 PGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLK 206 Query: 178 YKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP-WAKPEDPSLLEDPRIKA 236 +KP NQ+ECHPY TQ KL+++CQ IV+TAYSPLG+ P W P LL+D + + Sbjct: 207 HKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNS 266 Query: 237 IAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNW 296 + ++NKT AQ+++RF +QR +VVIPKS ERI ENF++FDF L+ ++M + + N+N Sbjct: 267 LGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNV 326 Query: 297 RVCALLSCTSHKDYPFHEEF 316 R LL H +YPFH+E+ Sbjct: 327 RFVELLMWRDHPEYPFHDEY 346 >2ALR-A nrPDB Length = 324 Score = 326 bits (835), Expect = 8e-90, Method: Compositional matrix adjust. Identities = 161/325 (49%), Positives = 226/325 (69%), Gaps = 12/325 (3%) Query: 2 ASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQE 61 AS +LL+ G KMP++GLGTWKS PGQV AVK A+ VGYRHIDCA +Y NE E+G A++E Sbjct: 2 ASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKE 61 Query: 62 KLRE-QVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120 + + V REELF+ SKLW T H V+ A +KTL+DL+L+YLDLYL+HWP F+ G Sbjct: 62 DVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD 121 Query: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180 FP + G + T+ +TW A+E LV +GLV+A+G+SNFN Q++ IL+ ++ P Sbjct: 122 NPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR--P 179 Query: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240 AV Q+ECHPYL Q +LI +CQ++G+ VTAYSPLGS DR W P++P LLE+P + A+A K Sbjct: 180 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK 239 Query: 241 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR-VC 299 + ++ AQ+L+R+ +QR ++ IPKS+TP RI +N KVFDF S ++M L + N+NWR + Sbjct: 240 YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIV 299 Query: 300 ALLSC--------TSHKDYPFHEEF 316 +L+ H YPF++ + Sbjct: 300 PMLTVDGKRVPRDAGHPLYPFNDPY 324 >2FVL-A nrPDB Length = 324 Score = 325 bits (833), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 152/317 (47%), Positives = 217/317 (68%), Gaps = 4/317 (1%) Query: 4 RLLLNNGAKMPILGLGTW---KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60 R+ LN+G MP+LG GT+ + P + E K+AI+ G+RHID A++Y NE +VG+AI+ Sbjct: 8 RVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIR 67 Query: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120 K+ + VKRE++F SKLWCT+ + +V+ A + +L L+LDY+DLYL+H+P KPG+ Sbjct: 68 SKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGE 127 Query: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180 P DE+G V+ ++ TW ME+ D GL K+IG+SNFN+ Q+EMILNKPGLKYKP Sbjct: 128 TPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPGLKYKP 187 Query: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP-DRPWAKPEDPSLLEDPRIKAIAA 239 NQ+ECHPYL Q KL+ +C+SK IV+ A+S LG+ + W P P LLEDP + A+A Sbjct: 188 VCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAK 247 Query: 240 KHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVC 299 KH +T A + +R+ +QR +VV+ KS +RI EN +VF+F+L+S+DM L NRN+R Sbjct: 248 KHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYV 307 Query: 300 ALLSCTSHKDYPFHEEF 316 + H DYPF +E+ Sbjct: 308 VMDFLMDHPDYPFSDEY 324 >4GAC-A nrPDB Length = 324 Score = 324 bits (830), Expect = 3e-89, Method: Compositional matrix adjust. Identities = 158/325 (48%), Positives = 223/325 (68%), Gaps = 12/325 (3%) Query: 2 ASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQE 61 AS +LL+ G KMP++GLGTWKS PGQV A+K A+ GYRHIDCA VY NE E+G A++E Sbjct: 2 ASSVLLHTGQKMPLIGLGTWKSEPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKE 61 Query: 62 KLRE-QVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120 + + V REELF+ SKLW T H V+ A +KTL+DL+L+YLDLYL+HWP F+ G Sbjct: 62 SVGSGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD 121 Query: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180 FP + G V T+ +TW A+E LV +GLVKA+G+SNFN Q++ +L+ ++ P Sbjct: 122 NPFPKNADGTVRYDSTHYKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVR--P 179 Query: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240 AV Q+ECHPYL Q +LI +C ++G+ VTAYSPLGS DR W P++P LLE+P + A+A K Sbjct: 180 AVLQVECHPYLAQNELIAHCHARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEK 239 Query: 241 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR-VC 299 H ++ AQ+L+R+ +QR ++ IPKS+ P RI +N +VFDF S ++M L + N+NWR + Sbjct: 240 HGRSPAQILLRWQVQRKVICIPKSINPSRILQNIQVFDFTFSPEEMKQLDALNKNWRYIV 299 Query: 300 ALLSC--------TSHKDYPFHEEF 316 +++ H YPF++ + Sbjct: 300 PMITVDGKRVPRDAGHPLYPFNDPY 324 >4JQA-A nrPDB Length = 331 Score = 323 bits (829), Expect = 4e-89, Method: Compositional matrix adjust. Identities = 154/314 (49%), Positives = 214/314 (68%), Gaps = 4/314 (1%) Query: 7 LNNGAKMPILGLGTW---KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKL 63 LN+G MP+LG GT+ + P + EAVK+AI+ G+ HID AHVY NE +VG+AI+ K+ Sbjct: 10 LNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKI 69 Query: 64 REQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFF 123 + VKRE++F SKLW H LV+ A +++L +L+LDY+DLYLIH+P KPG+E Sbjct: 70 ADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVI 129 Query: 124 PLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVN 183 P DE+G ++ ++ TW AME+ D GL K+IG+SNFNH +EMILNKPGLKYKP N Sbjct: 130 PKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCN 189 Query: 184 QIECHPYLTQEKLIQYCQSKGIVVTAYSPLGS-PDRPWAKPEDPSLLEDPRIKAIAAKHN 242 Q+ECHPY Q KL+ +C+SK IV+ AYS LGS + PW P P LLEDP + A+A KH Sbjct: 190 QVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHK 249 Query: 243 KTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALL 302 +T A + +R+ +QR +VV+ KS +RI +N +VF+F+L+S++M + NRN R L Sbjct: 250 RTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLD 309 Query: 303 SCTSHKDYPFHEEF 316 +YPF +E+ Sbjct: 310 IFAGPPNYPFSDEY 323 >1HQT-A nrPDB Length = 326 Score = 322 bits (825), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 159/325 (48%), Positives = 226/325 (69%), Gaps = 12/325 (3%) Query: 2 ASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQE 61 AS +LL+ G KMP++GLGTWKS PGQV A+K A+ VGYRHIDCA ++ NE E+G A+QE Sbjct: 4 ASCVLLHTGQKMPLIGLGTWKSEPGQVKAAIKYALTVGYRHIDCAAIFGNELEIGEALQE 63 Query: 62 KLRE-QVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120 + + V REELF+ SKLW T H V+ A +KTL+DL+L+YLDLYL+HWP F+ G Sbjct: 64 TVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD 123 Query: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180 FP + G + T+ DTW A+E LV +GLV+A+G+SNF+ Q++ +L+ ++ P Sbjct: 124 NPFPKNADGTIRYDATHYKDTWKALEALVAKGLVRALGLSNFSSRQIDDVLSVASVR--P 181 Query: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240 AV Q+ECHPYL Q +LI +CQ++G+ VTAYSPLGS DR W P +P LLE+P ++A+A K Sbjct: 182 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPNEPVLLEEPVVQALAEK 241 Query: 241 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR-VC 299 +N++ AQ+L+R+ +QR ++ IPKSVTP RI +N +VFDF S ++M L + N+N R + Sbjct: 242 YNRSPAQILLRWQVQRKVICIPKSVTPSRIPQNIQVFDFTFSPEEMKQLDALNKNLRFIV 301 Query: 300 ALLSC--------TSHKDYPFHEEF 316 +L+ H YPF++ + Sbjct: 302 PMLTVDGKRVPRDAGHPLYPFNDPY 326 >5JM5-A nrPDB Length = 332 Score = 320 bits (820), Expect = 5e-88, Method: Compositional matrix adjust. Identities = 151/314 (48%), Positives = 212/314 (67%), Gaps = 4/314 (1%) Query: 7 LNNGAKMPILGLGTW---KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKL 63 LN+G MP+LG GT+ + P + E K+AI+ G+RHID AH+Y NE +VG+AI+ K+ Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69 Query: 64 REQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFF 123 + VKRE++F SKLW T+H LV+ A + +L +LDY+DLYLIH P KPG+E Sbjct: 70 ADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELS 129 Query: 124 PLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVN 183 P DE+G V+ ++ TW AME+ D GL K+IG+SNFN Q+EMILNKPGLKYKP N Sbjct: 130 PTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCN 189 Query: 184 QIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP-DRPWAKPEDPSLLEDPRIKAIAAKHN 242 Q+ECHPY + KL+ +C+SK IV+ AYS LGS D+ W P P LLEDP + A+A KH Sbjct: 190 QVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHK 249 Query: 243 KTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALL 302 +T A + +R+ +QR +VV+ KS +RI +N +VF+F+L+++DM + +RN Sbjct: 250 RTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSD 309 Query: 303 SCTSHKDYPFHEEF 316 S SH +YP+ +E+ Sbjct: 310 SFASHPNYPYSDEY 323 >4HBK-A nrPDB Length = 344 Score = 317 bits (813), Expect = 3e-87, Method: Compositional matrix adjust. Identities = 157/312 (50%), Positives = 215/312 (68%), Gaps = 5/312 (1%) Query: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64 L +NNG +P++GLGTW SPPG+V AVK A+++GYRH+DCA+VY+NE E+G A++ L Sbjct: 38 LKMNNGRSIPVIGLGTWNSPPGEVGAAVKKALEIGYRHLDCAYVYRNEAEIGEALENALN 97 Query: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124 +KRE++FI SKLW T+ V+ AC++TL +L+L+YLDLYLIHWP K G + FP Sbjct: 98 SLRLKREDIFITSKLWNTFFRPEHVRKACEETLKNLRLNYLDLYLIHWPVPLKHGGDLFP 157 Query: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184 D +G + + DTW ME+LVDEGLVK+IG+SNFN Q++ IL + KPA Q Sbjct: 158 TDSNGQLCLDNVPHEDTWKEMEKLVDEGLVKSIGLSNFNKRQIQNILEH--CRIKPANLQ 215 Query: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKT 244 IE H KL++Y QS G+ VTAY+PLGSP P +LL P + IA +H KT Sbjct: 216 IEIHANFPNIKLVEYAQSVGLTVTAYAPLGSPAH---SPGKVNLLTKPCVLEIAHRHKKT 272 Query: 245 TAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSC 304 AQVL+R+ +QR L+V+PKSVT +RI ENF+VFDF+LS+++M L + + N R LL Sbjct: 273 PAQVLLRYLLQRKLIVVPKSVTFKRIEENFQVFDFQLSNEEMHELNTESLNERQFTLLQM 332 Query: 305 TSHKDYPFHEEF 316 + H++YPF EE+ Sbjct: 333 SGHQEYPFKEEY 344 >2HE8-A nrPDB Length = 323 Score = 304 bits (778), Expect = 4e-83, Method: Compositional matrix adjust. Identities = 144/316 (45%), Positives = 208/316 (65%), Gaps = 4/316 (1%) Query: 5 LLLNNGAKMPILGLGT---WKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQE 61 ++LN+G +P+LG GT + P + E K+AID G+ H D A VY E+ VG AI+ Sbjct: 8 VILNDGNFIPVLGFGTALPLECPKSKAKELTKIAIDAGFHHFDSASVYNTEDHVGEAIRS 67 Query: 62 KLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKE 121 K+ + V+RE++F SK+WCT LV+ + +++L L+ DY+DLYLIH+P KPG+E Sbjct: 68 KIADGTVRREDIFYTSKVWCTSLHPELVRASLERSLQKLQFDYVDLYLIHYPMALKPGEE 127 Query: 122 FFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPA 181 FP+DE G ++ ++ TW AME+ D GL K+IG+SNFN+ Q+EMILNKPGLKYKP Sbjct: 128 NFPVDEHGKLIFDRVDLCATWEAMEKCKDAGLTKSIGVSNFNYRQLEMILNKPGLKYKPV 187 Query: 182 VNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDR-PWAKPEDPSLLEDPRIKAIAAK 240 NQ+ECHPYL Q KL+ +C+SK IV+ AY LG+ W P LL++P + ++A K Sbjct: 188 CNQVECHPYLNQMKLLDFCKSKDIVLVAYGVLGTQRYGGWVDQNSPVLLDEPVLGSMAKK 247 Query: 241 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA 300 +N+T A + +R+ +QR +VV+ S+ ERI EN +VF+F+LSS+DM L NRN R Sbjct: 248 YNRTPALIALRYQLQRGIVVLNTSLKEERIKENMQVFEFQLSSEDMKVLDGLNRNMRYIP 307 Query: 301 LLSCTSHKDYPFHEEF 316 H ++PF +E+ Sbjct: 308 AAIFKGHPNWPFLDEY 323 >1AFS-A nrPDB Length = 323 Score = 303 bits (775), Expect = 9e-83, Method: Compositional matrix adjust. Identities = 148/319 (46%), Positives = 210/319 (65%), Gaps = 4/319 (1%) Query: 1 MASRLLLNNGAKMPILGLGTW---KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGV 57 ++ R+ LN+G +P+LG GT K +V +A K+AID G+RH D A++Y+ E EVG Sbjct: 4 ISLRVALNDGNFIPVLGFGTTVPEKVAKDEVIKATKIAIDNGFRHFDSAYLYEVEEEVGQ 63 Query: 58 AIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFK 117 AI+ K+ + VKRE++F SKLW T+H LV+ +KTL +LDY+DLY+IH+P + Sbjct: 64 AIRSKIEDGTVKREDIFYTSKLWSTFHRPELVRTCLEKTLKSTQLDYVDLYIIHFPMALQ 123 Query: 118 PGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK 177 PG FFP DE G ++ +I DTW AME+ D GL K+IG+SNFN Q+E ILNKPGLK Sbjct: 124 PGDIFFPRDEHGKLLFETVDICDTWEAMEKCKDAGLAKSIGVSNFNCRQLERILNKPGLK 183 Query: 178 YKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP-DRPWAKPEDPSLLEDPRIKA 236 YKP NQ+ECH YL Q K++ YC+SK I++ +Y LGS D+ W + P LL+DP + A Sbjct: 184 YKPVCNQVECHLYLNQSKMLDYCKSKDIILVSYCTLGSSRDKTWVDQKSPVLLDDPVLCA 243 Query: 237 IAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNW 296 IA K+ +T A V +R+ +QR +V + +S +RI E +VF+F+L+S+DM L NRN+ Sbjct: 244 IAKKYKQTPALVALRYQLQRGVVPLIRSFNAKRIKELTQVFEFQLASEDMKALDGLNRNF 303 Query: 297 RVCALLSCTSHKDYPFHEE 315 R H ++PF +E Sbjct: 304 RYNNAKYFDDHPNHPFTDE 322 >5UXF-A nrPDB Length = 342 Score = 296 bits (757), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 146/314 (46%), Positives = 200/314 (63%), Gaps = 4/314 (1%) Query: 7 LNNGAKMPILGLGTWKS---PPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKL 63 LN+G +P LG GT+K P + EA +A+DVGYRH+D A+ YQ E E+G AIQ + Sbjct: 29 LNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQAIQSAI 88 Query: 64 REQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFF 123 VVKRE+LF+ +KLWCT LVK A +K+L L+LDY+DLY++H+P K G F Sbjct: 89 AAGVVKREDLFVTTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMKSGDNDF 148 Query: 124 PLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVN 183 P++E G + + DTW +EE D GLVK+IG+SNFNH Q+E ILNKPGLKYKP N Sbjct: 149 PVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPGLKYKPVCN 208 Query: 184 QIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPD-RPWAKPEDPSLLEDPRIKAIAAKHN 242 Q+ECH YL Q KL+ YC+SK IV+ AY LG+ + W P LL DP + +A K+ Sbjct: 209 QVECHLYLNQRKLLDYCESKDIVLVAYGALGTQRYKEWVDQNSPVLLNDPVLCDVAKKNK 268 Query: 243 KTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALL 302 ++ A + +R+ +QR +V + +S + EN +VF F+LS +DM TL N+N+R Sbjct: 269 RSPALIALRYLIQRGIVPLAQSFKENEMRENLQVFGFQLSPEDMKTLDGLNKNFRYLPAE 328 Query: 303 SCTSHKDYPFHEEF 316 H +YPF EE+ Sbjct: 329 FLVDHPEYPFVEEY 342 >3H7U-A nrPDB Length = 335 Score = 256 bits (653), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 130/275 (47%), Positives = 179/275 (65%), Gaps = 10/275 (3%) Query: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66 LN GAK P +GLGTW++ PG V +AV A+ +GYRHIDCA +Y NE E+G +++ ++ Sbjct: 30 LNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKLFEDR 89 Query: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126 VVKRE+LFI SKLWCT H+ V A +TL DL+L+Y+DLYLIHWP K G + Sbjct: 90 VVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVGIKPE 149 Query: 127 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 186 N++P D I TW AME L D G +AIG+SNF+ ++ +L + PAVNQ+E Sbjct: 150 ---NLLPVD--IPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA--RVPPAVNQVE 202 Query: 187 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTA 246 CHP Q KL ++C+SKG+ ++AYSPLGSP W K + +L++P + +A K K+ A Sbjct: 203 CHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD---VLKNPILNMVAEKLGKSPA 259 Query: 247 QVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFEL 281 QV +R+ +Q V+PKS RI ENF VFD+ + Sbjct: 260 QVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSI 294 >5JH1-A nrPDB Length = 309 Score = 246 bits (627), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 131/280 (46%), Positives = 177/280 (63%), Gaps = 11/280 (3%) Query: 2 ASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQE 61 A +LN GAK+P +GLG+W+S PG V AV A+ GYRHIDCA VY NE E+G+A+++ Sbjct: 1 ARHFVLNTGAKIPSVGLGSWQSDPGVVGNAVYAAVKAGYRHIDCARVYGNEKEIGLALKK 60 Query: 62 KLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKE 121 E VVKRE++FI SKLW +H V A +L+DL+L+YLDLYLIHWP K G Sbjct: 61 LFEEGVVKREDMFITSKLWNDHHAPEDVPEALNDSLNDLQLEYLDLYLIHWPFRVKKGTN 120 Query: 122 FFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPA 181 P N V D TW AME+L D G +AIG+SNF+ ++ +L + PA Sbjct: 121 TSP----ENFVTPD--FPATWGAMEKLYDAGKARAIGVSNFSSKKLGDLLAVA--RVPPA 172 Query: 182 VNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKH 241 V+Q+ECHP Q KL +CQS G+ +TAYSPLGSP W + ++L++P I +IA K Sbjct: 173 VDQVECHPGWQQTKLHSFCQSTGVHLTAYSPLGSPGTTWM---NGNVLKEPIIISIAEKL 229 Query: 242 NKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFEL 281 KT+AQV +R+ +Q V+PKS ERI +N V+D+ + Sbjct: 230 GKTSAQVALRWNIQMGHSVLPKSTNEERIKQNLDVYDWSI 269 >5ZCM-A nrPDB Length = 341 Score = 233 bits (595), Expect = 6e-62, Method: Compositional matrix adjust. Identities = 131/301 (43%), Positives = 181/301 (60%), Gaps = 12/301 (3%) Query: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66 LN+G +MP++G G WK + V AI VGYR D A Y N E+G I L E Sbjct: 26 LNSGYEMPLVGFGCWKVDNATCADTVYNAIKVGYRLFDAAMDYGNCKEIGEGINRALDEG 85 Query: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFK--PGKEFFP 124 +V R+ELFI SKLW +YH+ V+ A +K LSD+KLDY+DL+LIH+P FK P +E +P Sbjct: 86 LVARDELFITSKLWNSYHDPKNVELALKKVLSDMKLDYIDLFLIHFPIAFKFVPFEEKYP 145 Query: 125 ----LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180 + N D +L+TW AME+L G K+IGISNF+ + +L G + KP Sbjct: 146 PAFYCGDGDNFHYEDVPLLETWKAMEKLTKGGKAKSIGISNFSAALIYDLLR--GAEIKP 203 Query: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPD----RPWAKPEDPSLLEDPRIKA 236 AV QIE HPYL Q +LI+Y QS+GI +TAYS G + + P+L E I + Sbjct: 204 AVLQIEHHPYLQQPRLIEYVQSQGIAITAYSSFGPQSFLELKHSKALDTPTLFEHKTITS 263 Query: 237 IAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNW 296 IA K+ KT AQVL+R+ QR++ +IPKS P+R+ +N +V DF LS +D + +++ Sbjct: 264 IADKYKKTPAQVLLRWASQRDIAIIPKSNNPDRLLQNLEVNDFNLSKEDFDEISKLDQDL 323 Query: 297 R 297 R Sbjct: 324 R 324 >3WCZ-A nrPDB Length = 308 Score = 231 bits (589), Expect = 3e-61, Method: Compositional matrix adjust. Identities = 124/311 (39%), Positives = 184/311 (59%), Gaps = 22/311 (7%) Query: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60 LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +VG I Sbjct: 10 LNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 69 Query: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120 E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP Sbjct: 70 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 127 Query: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180 D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ ++ P Sbjct: 128 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--P 176 Query: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240 +NQIE +P TQE L+ +CQS GI V AYSP G P +DP + A+A K Sbjct: 177 VINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANK 236 Query: 241 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA 300 + K+ Q+L+R+ + R L+ IPKS +RIA+N +FDF+L+ +++ + +N+N RV Sbjct: 237 YRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKNHRV-- 294 Query: 301 LLSCTSHKDYP 311 + + KDYP Sbjct: 295 -IDISDWKDYP 304 >1K8C-A nrPDB Length = 322 Score = 227 bits (578), Expect = 6e-60, Method: Compositional matrix adjust. Identities = 131/306 (42%), Positives = 176/306 (57%), Gaps = 18/306 (5%) Query: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66 L++G MP +G G WK E V AI GYR D A Y NE EVG ++ + E Sbjct: 10 LSSGHLMPSIGFGCWKLANATAGEQVYQAIKAGYRLFDGAEDYGNEKEVGDGVKRAIDEG 69 Query: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFK--PGKEFFP 124 +VKREE+F+ SKLW YH+ V+ A KTL+DLK+DY+DL+LIH+P FK P +E +P Sbjct: 70 LVKREEIFLTSKLWNNYHDPKNVETALNKTLADLKVDYVDLFLIHFPIAFKFVPIEEKYP 129 Query: 125 ----LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180 + N V D IL+TW A+E+LV G +K+IG+SNF + +L G KP Sbjct: 130 PGFYCGDGNNFVYEDVPILETWKALEKLVAAGKIKSIGVSNFPGALLLDLLR--GATIKP 187 Query: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPD----RPWAKPEDPSLLEDPRIKA 236 AV Q+E HPYL Q KLI++ Q G+ +TAYS G P+L IKA Sbjct: 188 AVLQVEHHPYLQQPKLIEFAQKAGVTITAYSSFGPQSFVEMNQGRALNTPTLFAHDTIKA 247 Query: 237 IAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTL------L 290 IAAK+NKT A+VL+R+ QR + VIPKS PER+ +N F+L+ +D + L Sbjct: 248 IAAKYNKTPAEVLLRWAAQRGIAVIPKSNLPERLVQNRSFNTFDLTKEDFEEIAKLDIGL 307 Query: 291 SYNRNW 296 +N W Sbjct: 308 RFNDPW 313 >1QWK-A nrPDB Length = 317 Score = 226 bits (577), Expect = 8e-60, Method: Compositional matrix adjust. Identities = 127/319 (39%), Positives = 180/319 (56%), Gaps = 23/319 (7%) Query: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66 L+NG +MP++GLGTW+S P +V AVK A+ GYR ID A VYQNE +G AI+E L E Sbjct: 10 LSNGVEMPVIGLGTWQSSPAEVITAVKTAVKAGYRLIDTASVYQNEEAIGTAIKELLEEG 69 Query: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126 VVKREELFI +K W G ++G +++L L+L+Y+DLYL H P F D Sbjct: 70 VVKREELFITTKAWTHELAPGKLEGGLRESLKKLQLEYVDLYLAHMPAAFND-------D 122 Query: 127 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVN-QI 185 S ++ + + D W + + GL KA+G+SN+N+ Q+ L L P N Q+ Sbjct: 123 MSEHIA---SPVEDVWRQFDAVYKAGLAKAVGVSNWNNDQISRAL---ALGLTPVHNSQV 176 Query: 186 ECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDR-----PWAKPED----PSLLEDPRIKA 236 E H Y Q + +C+ I VT+Y+ LGSP R P + D PS L+D + A Sbjct: 177 ELHLYFPQHDHVDFCKKHNISVTSYATLGSPGRVNFTLPTGQKLDWAPAPSDLQDQNVLA 236 Query: 237 IAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNW 296 +A K +KT AQVL+R+ + R ++PKS+ RI ENF+VFDF L+ +D+ L + Sbjct: 237 LAEKTHKTPAQVLLRYALDRGCAILPKSIQENRIKENFEVFDFSLTEEDIAKLEESKNSQ 296 Query: 297 RVCALLSCTSHKDYPFHEE 315 R+ T H + F E Sbjct: 297 RLFLQDFMTGHPEDAFAAE 315 >3KRB-A nrPDB Length = 334 Score = 226 bits (575), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 128/302 (42%), Positives = 177/302 (58%), Gaps = 21/302 (6%) Query: 14 PILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQV--VKRE 71 P LG GTW++PP V AV+ A+ GYRHIDCA+VYQNE +G A + ++ +KRE Sbjct: 26 PRLGFGTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKRE 85 Query: 72 ELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK--EFFPLDESG 129 +++I SKLW H LV+ C+KT+SDL++DYLDL+L+HWP F + FP D G Sbjct: 86 DVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEG 145 Query: 130 NVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHP 189 + + DTW AME+LV+EGLVK IG+SN+ + +LN K KP VNQIE HP Sbjct: 146 RAMLEKVPLADTWRAMEQLVEEGLVKHIGVSNYTVPLLADLLNY--AKIKPLVNQIEIHP 203 Query: 190 YLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPS------LLEDPRIKAIAAKHNK 243 + + +++C GI VTAYSP+G +A P DPS +LE +KAIA Sbjct: 204 WHPNDATVKFCLDNGIGVTAYSPMGG---SYADPRDPSGTQKNVILECKTLKAIADAKGT 260 Query: 244 TTAQVLIRFPMQR----NLVVIPKSVTPERIAENFKVFDFELSSQDMTTL--LSYNRNWR 297 + V + + +++ VIPKS TP RI NFK + +LS DM + + N+ R Sbjct: 261 SPHCVALAWHVKKWNTSMYSVIPKSQTPARIEANFKCTEVQLSDDDMDAINNIHLNKRIR 320 Query: 298 VC 299 C Sbjct: 321 FC 322 >5Z6T-A nrPDB Length = 343 Score = 225 bits (574), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 131/306 (42%), Positives = 177/306 (57%), Gaps = 22/306 (7%) Query: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66 LN+G MP +G G WK +E + AI GYR D A Y NE VG +++ + E Sbjct: 31 LNSGYDMPAVGFGCWKVDVDTCSEQIYRAIKTGYRLFDGAEDYANEKLVGAGVKKAIDEG 90 Query: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126 +VKRE+LF+ SKLW YH V+ A +TLSDL++DY+DL+LIH+P FK F PL+ Sbjct: 91 IVKREDLFLTSKLWNNYHHPDNVEKALNRTLSDLQVDYVDLFLIHFPVTFK----FVPLE 146 Query: 127 E----------SGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176 E N D IL+TW A+E+LV G +++IG+SNF + +L G Sbjct: 147 EKYPPGFYCGKGDNFDYEDVPILETWKALEKLVKAGKIRSIGVSNFPGALLLDLLR--GA 204 Query: 177 KYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP-----DRPWAKPEDPSLLED 231 KP+V Q+E HPYL Q +LI++ QS+GI VTAYS G ++ A P L E+ Sbjct: 205 TIKPSVLQVEHHPYLQQPRLIEFAQSRGIAVTAYSSFGPQSFVELNQGRALNTSP-LFEN 263 Query: 232 PRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLS 291 IKAIAAKH K+ AQVL+R+ QR + +IPKS T R+ EN V F+L QD + Sbjct: 264 ETIKAIAAKHGKSPAQVLLRWSSQRGIAIIPKSNTVPRLLENKDVNSFDLDEQDFADIAK 323 Query: 292 YNRNWR 297 + N R Sbjct: 324 LDINLR 329 >3H7R-A nrPDB Length = 331 Score = 225 bits (573), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 126/308 (40%), Positives = 185/308 (60%), Gaps = 16/308 (5%) Query: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66 LN GAK+P +GLGT+ V A++ AI +GYRHIDCA +Y NE E+G +++ + + Sbjct: 30 LNTGAKLPCVGLGTY----AMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKLIGDG 85 Query: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126 VKREELFI SKLW H V A +KTL DL++DY+DLYLIHWP K + P Sbjct: 86 FVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKK-ESLMPTP 144 Query: 127 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 186 E + + +I TW AME L D G +AIG+SNF+ ++ +LN + PAVNQ+E Sbjct: 145 E----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA--RVTPAVNQVE 198 Query: 187 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTA 246 CHP Q+ L + C+SKG+ ++ YSPLGS + + + +L++P + +A K KTTA Sbjct: 199 CHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLK---VLQNPIVTEVAEKLGKTTA 255 Query: 247 QVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSCTS 306 QV +R+ +Q V+PKS + R+ EN VFD+ + +D+ T S + C + Sbjct: 256 QVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSI-PEDLFTKFSNIPQEKFCRATEF-A 313 Query: 307 HKDYPFHE 314 H+ + F++ Sbjct: 314 HETHGFYK 321 >4F40-A nrPDB Length = 288 Score = 224 bits (570), Expect = 6e-59, Method: Compositional matrix adjust. Identities = 129/298 (43%), Positives = 173/298 (58%), Gaps = 37/298 (12%) Query: 5 LLLNNGAKMPILGLGTWKSPPGQVTE-AVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKL 63 + L+NG KMP GLG W+SP G+VTE AVK A+ GYRHID A +Y+NE VG L Sbjct: 13 VTLSNGVKMPQFGLGVWQSPAGEVTENAVKWALCAGYRHIDTAAIYKNEESVGAG----L 68 Query: 64 REQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG----FKPG 119 R V RE++FI +KLW T A +++ L +DY+DLYLIHWP G K G Sbjct: 69 RASGVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRGKDILSKEG 128 Query: 120 KEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYK 179 K++ LD+W A E+L E V+AIG+SNF+ +E +L Sbjct: 129 KKY----------------LDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAM--CTVT 170 Query: 180 PAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAA 239 P VNQ+E HP Q L +C +K I V A+SPLG LL +P + AI A Sbjct: 171 PMVNQVELHPLNNQADLRAFCDAKQIKVEAWSPLGQG----------KLLSNPILSAIGA 220 Query: 240 KHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR 297 K+NKT AQV++R+ +Q+NL+ IPKSV ERI EN +FDFEL ++D+ ++ + N N R Sbjct: 221 KYNKTAAQVILRWNIQKNLITIPKSVHRERIEENADIFDFELGAEDVMSIDALNTNSR 278 >1VBJ-A nrPDB Length = 281 Score = 213 bits (543), Expect = 7e-56, Method: Compositional matrix adjust. Identities = 123/298 (41%), Positives = 165/298 (55%), Gaps = 37/298 (12%) Query: 1 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKV-AIDVGYRHIDCAHVYQNENEVGVAI 59 + L L+NG MP+LG G WK G E + AI GYRHID A +Y+NE G AI Sbjct: 8 LTQSLKLSNGVMMPVLGFGMWKLQDGNEAETATMWAIKSGYRHIDTAAIYKNEESAGRAI 67 Query: 60 QEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPG 119 V REELF+ +KLW + A +K++ L L+Y+DLYLIHWP G Sbjct: 68 AS----CGVPREELFVTTKLWNSDQGYESTLSAFEKSIKKLGLEYVDLYLIHWP-----G 118 Query: 120 KEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYK 179 K+ F +DTW A E+L + V+AIG+SNF+ +E +L K Sbjct: 119 KDKF---------------IDTWKAFEKLYADKKVRAIGVSNFHEHHIEELLKH--CKVA 161 Query: 180 PAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAA 239 P VNQIE HP L Q+ L +YC+SK I VTA+SPLG L+ED R+KAI Sbjct: 162 PMVNQIELHPLLNQKALCEYCKSKNIAVTAWSPLGQG----------HLVEDARLKAIGG 211 Query: 240 KHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR 297 K+ KT AQV++R+ +Q ++ IPKS RI EN +FDFEL+++D+ + N R Sbjct: 212 KYGKTAAQVMLRWEIQAGVITIPKSGNEARIKENGNIFDFELTAEDIQVIDGMNAGHR 269 >2BGQ-A nrPDB Length = 344 Score = 208 bits (530), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 120/295 (40%), Positives = 168/295 (56%), Gaps = 17/295 (5%) Query: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAI-DVGYRHIDCAHVYQNENEVGVAIQEKL 63 +L +G MP +GLGTW++ +V+ AI + GYRH+D A Y E EVG ++ + Sbjct: 40 FVLKSGHAMPAVGLGTWRAG-SDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLKAAM 98 Query: 64 REQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFF 123 E + R++LF+ SK+WCT V+ A + TL DL+LDY+DLY IHWP K G Sbjct: 99 -EAGIDRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLKDGAHMP 157 Query: 124 PLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVN 183 P E+G V+ D W ME LV +GLVK IG+ N+ ++ +L K PAV Sbjct: 158 P--EAGEVLEFDME--GVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSA--KIPPAVC 211 Query: 184 QIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNK 243 Q+E HP +K+ + C+ GI +TAYSPLGS ++ +L DP ++ +A K NK Sbjct: 212 QMEMHPGWKNDKIFEACKKHGIHITAYSPLGSSEK--------NLAHDPVVEKVANKLNK 263 Query: 244 TTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRV 298 T QVLI++ +QR VIPKS ERI EN +VF +E+ +D L S RV Sbjct: 264 TPGQVLIKWALQRGTSVIPKSSKDERIKENIQVFGWEIPEEDFKVLCSIKDEKRV 318 >4GIE-A nrPDB Length = 290 Score = 206 bits (523), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 117/298 (39%), Positives = 171/298 (57%), Gaps = 36/298 (12%) Query: 5 LLLNNGAKMPILGLGTWKSPPG-QVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKL 63 + L+N +MP LGLG W++ G + AV+ AI+ GYRHID A++Y NE VG I Sbjct: 16 VTLHNSVRMPQLGLGVWRAQDGAETANAVRWAIEAGYRHIDTAYIYSNERGVGQGI---- 71 Query: 64 REQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFF 123 RE V REE+++ +K+W + A +++ L L+Y+DLYLIHWP GK+ F Sbjct: 72 RESGVPREEVWVTTKVWNSDQGYEKTLAAFERSRELLGLEYIDLYLIHWP-----GKKKF 126 Query: 124 PLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFN-HLQVEMILNKPGLKYKPAV 182 +DTW A+E+L +E V+AIG+SNF H E+ K +P V Sbjct: 127 ---------------VDTWKALEKLYEEKKVRAIGVSNFEPHHLTELF---KSCKIRPMV 168 Query: 183 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHN 242 NQ+E HP Q L ++C+ I +TA+SPLGS E+ +L++ + IA KHN Sbjct: 169 NQVELHPLFQQRTLREFCKQHNIAITAWSPLGSG-------EEAGILKNHVLGEIAKKHN 221 Query: 243 KTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA 300 K+ AQV+IR+ +Q +V IPKS RI ENF V+DF+L+ ++M + N + R+ A Sbjct: 222 KSPAQVVIRWDIQHGIVTIPKSTNKGRIQENFNVWDFKLTEEEMRQIDELNEDKRIGA 279 >1VP5-A nrPDB Length = 298 Score = 197 bits (500), Expect = 6e-51, Method: Compositional matrix adjust. Identities = 113/308 (36%), Positives = 174/308 (56%), Gaps = 40/308 (12%) Query: 4 RLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKL 63 ++ LNNG +MPILG G ++ PP + E V AI VGYR ID A Y NE VG AI+ + Sbjct: 17 KVTLNNGVEMPILGYGVFQIPPEKTEECVYEAIKVGYRLIDTAASYMNEEGVGRAIKRAI 76 Query: 64 REQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFF 123 E +V+REELF+ +KLW + K A +K+L L+L+Y+DLYLIH P G Sbjct: 77 DEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQPFG-------- 128 Query: 124 PLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNF--NHLQVEMILNKPGLKYKPA 181 ++ W AMEE+ +GLV+AIG+SNF + L M+ + + PA Sbjct: 129 -------------DVHCAWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHH----EIVPA 171 Query: 182 VNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKH 241 VNQIE HP+ +++ I++ ++ I A+ P + ++ ++ +++IA K+ Sbjct: 172 VNQIEIHPFYQRQEEIEFMRNYNIQPEAWGPFAEGRK--------NIFQNGVLRSIAEKY 223 Query: 242 NKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCAL 301 KT AQV++R+ Q+ +V IPK+V ER+ EN +FDFEL+ +DM + + + Sbjct: 224 GKTVAQVILRWLTQKGIVAIPKTVRRERMKENISIFDFELTQEDMEKIATLDEGQS---- 279 Query: 302 LSCTSHKD 309 + SH+D Sbjct: 280 -AFFSHRD 286 >3D3F-A nrPDB Length = 275 Score = 195 bits (496), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 125/293 (42%), Positives = 172/293 (58%), Gaps = 37/293 (12%) Query: 7 LNNGAKMPILGLGTWKSPPG-QVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLRE 65 L+NG +MP GLG +K G + TE+VK AI GYR ID A +Y+NE VG+ I +E Sbjct: 10 LHNGVEMPWFGLGVFKVENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIGI----KE 65 Query: 66 QVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPL 125 V REELFI SK+W A +K+L L+LDYLDLYLIHWP GK+ + Sbjct: 66 SGVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP-----GKDKYK- 119 Query: 126 DESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQI 185 DTW A+E+L +G ++AIG+SNF +E +L +K P VNQ+ Sbjct: 120 --------------DTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIK--PMVNQV 163 Query: 186 ECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTT 245 E HP LTQ++L YC+ +GI + A+SPL LL++ + IA KHNK+ Sbjct: 164 EFHPRLTQKELRDYCKGQGIQLEAWSPLMQG----------QLLDNEVLTQIAEKHNKSV 213 Query: 246 AQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRV 298 AQV++R+ +Q +V IPKS+ RI EN +FDFELS +DM + + N++ RV Sbjct: 214 AQVILRWDLQHGVVTIPKSIKEHRIIENADIFDFELSQEDMDKIDALNKDERV 266 >1MZR-A nrPDB Length = 296 Score = 190 bits (483), Expect = 6e-49, Method: Compositional matrix adjust. Identities = 108/292 (36%), Positives = 164/292 (56%), Gaps = 34/292 (11%) Query: 7 LNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ 66 L +G MP LGLG W++ +V A++ A++VGYR ID A Y+NE VG A L+ Sbjct: 30 LQDGNVMPQLGLGVWQASNEEVITAIQKALEVGYRSIDTAAAYKNEEGVGKA----LKNA 85 Query: 67 VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLD 126 V REELFI +KLW H++ + A +L L+LDY+DLYL+HWP Sbjct: 86 SVNREELFITTKLWNDDHKR--PREALLDSLKKLQLDYIDLYLMHWP------------- 130 Query: 127 ESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIE 186 VP+ + ++ W M EL EGL+K+IG+ NF ++ ++++ G+ P +NQIE Sbjct: 131 -----VPAIDHYVEAWKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETGVT--PVINQIE 183 Query: 187 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTA 246 HP + Q +L + + I ++SPL + + + I+ +A K+ KT A Sbjct: 184 LHPLMQQRQLHAWNATHKIQTESWSPLAQGGK--------GVFDQKVIRDLADKYGKTPA 235 Query: 247 QVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRV 298 Q++IR+ + LVVIPKSVTP RIAENF V+DF L ++ + ++ R+ Sbjct: 236 QIVIRWHLDSGLVVIPKSVTPSRIAENFDVWDFRLDKDELGEIAKLDQGKRL 287 >4OTK-A nrPDB Length = 318 Score = 177 bits (450), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 110/300 (36%), Positives = 157/300 (52%), Gaps = 40/300 (13%) Query: 2 ASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQE 61 A + LN+ MP+LGLG + + AV A+++G R ID A+ Y NE VG AI Sbjct: 46 APSITLNDEHTMPVLGLGVAELSDDETERAVSAALEIGCRLIDTAYAYGNEAAVGRAIAA 105 Query: 62 KLREQVVKREELFIVSKLWCTYHEKGLVKG--ACQKTLSDLKLDYLDLYLIHWPTGFKPG 119 V REELF+ +KL ++G + AC+ +L L LDY+DLYLIHWP Sbjct: 106 S----GVAREELFVTTKLATP--DQGFTRSQEACRASLDRLGLDYVDLYLIHWP------ 153 Query: 120 KEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKY- 178 P +D W M + EG ++IG+SNF +E +++ L + Sbjct: 154 ------------APPVGKYVDAWGGMIQSRGEGHARSIGVSNFTAENIENLID---LTFV 198 Query: 179 KPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIA 238 PAVNQIE HP L Q++L + +V +Y PL LL++P + +IA Sbjct: 199 TPAVNQIELHPLLNQDELRKANAQHTVVTQSYCPLALG----------RLLDNPTVTSIA 248 Query: 239 AKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRV 298 +++ KT AQVL+R+ +Q V+ +S PERIA NF VFDFEL+++ M L N RV Sbjct: 249 SEYVKTPAQVLLRWNLQLGNAVVVRSARPERIASNFDVFDFELAAEHMDALGGLNDGTRV 308 >4MHB-A nrPDB Length = 297 Score = 176 bits (446), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 113/308 (36%), Positives = 163/308 (52%), Gaps = 49/308 (15%) Query: 7 LNNGAKMPILGLGTWK-SPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLRE 65 LNNG MP+LG G ++ + + AV AI+ GYR ID A YQNE +VG A L+ Sbjct: 20 LNNGIAMPLLGFGVFQMTNTAECERAVIDAIETGYRLIDTAASYQNETQVGNA----LKL 75 Query: 66 QVVKREELFIVSKLWC--TYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFF 123 + R+ELFI +KLW TY+E K +++L+ L+LDY+DLYLIH P G Sbjct: 76 SGIARDELFITTKLWLQDTYYEGA--KAQFERSLNRLQLDYVDLYLIHQPYG-------- 125 Query: 124 PLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNF--NHLQVEMILNKPGLKYKPA 181 ++ W AMEEL G ++AIG+SNF + L M NK PA Sbjct: 126 -------------DVHGAWRAMEELHQAGKIRAIGVSNFHPDRLADLMAFNK----IIPA 168 Query: 182 VNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKH 241 VNQIE +P+ Q + + QS+GI A++P L ++P + AI K+ Sbjct: 169 VNQIEVNPFNQQLHAVPWMQSRGIQPEAWAPFAEGRN--------GLFQNPVLTAIGEKY 220 Query: 242 NKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCAL 301 K+ QV++R+ QR +V + KSV R+ EN + DFELS++DM + + + A Sbjct: 221 GKSVGQVVLRWIFQRGIVSLAKSVRKGRMEENINILDFELSAEDMLQIAALD-----TAT 275 Query: 302 LSCTSHKD 309 + SH+D Sbjct: 276 SAFFSHRD 283 >4IJC-A nrPDB Length = 344 Score = 171 bits (433), Expect = 4e-43, Method: Compositional matrix adjust. Identities = 107/284 (37%), Positives = 170/284 (59%), Gaps = 28/284 (9%) Query: 7 LNNGAKMPILGLGTWKSPPGQVTE---AVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKL 63 LNNG ++P LGLGT +P ++ E AVK AI GYRHID A Y+ E VG AI+E L Sbjct: 27 LNNGVRIPALGLGT-ANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELL 85 Query: 64 REQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKE-- 121 + +KRE+LFI +K+W ++ V + ++L L L+Y+DL L HWP F+ K+ Sbjct: 86 EDGSIKREDLFITTKVWPVLWDE--VDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPK 143 Query: 122 ------FFPLDESGNVV-PSDTNILDTWAAMEELV---DEGLVKAIGISNFNHLQVEMIL 171 P+D+SG + +D + L+T+ +E++ ++ V+AIG+SNF+ +E ++ Sbjct: 144 GISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLI 203 Query: 172 NKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLED 231 + + KP VNQ+E HP+L Q +L ++C I++TAYSPLGS P L+ Sbjct: 204 KE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN--------LKI 253 Query: 232 PRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFK 275 P +K +A K+N T +LI + +++ +VIP+S+ P RI+ + + Sbjct: 254 PLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIE 297 >1A80-A nrPDB Length = 277 Score = 171 bits (432), Expect = 5e-43, Method: Compositional matrix adjust. Identities = 101/287 (35%), Positives = 151/287 (52%), Gaps = 36/287 (12%) Query: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64 ++LN+G +P LG G +K PP AV+ A++VGYRHID A +Y NE + + Sbjct: 5 IVLNDGNSIPQLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEE----GVGAAIA 60 Query: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124 + R++LFI +KLW H+ A ++L+ L LD +DLYL+HWPT Sbjct: 61 ASGIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPT---------- 110 Query: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184 P+ N + W M EL GL ++IG+SN +E I+ G+ PAVNQ Sbjct: 111 --------PAADNYVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGV--VPAVNQ 160 Query: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP--DRPWAKPEDPSLLEDPRIKAIAAKHN 242 IE HP Q ++ + + + + ++ PLG D A+P + A AA H Sbjct: 161 IELHPAYQQREITDWAAAHDVKIESWGPLGQGKYDLFGAEP----------VTAAAAAHG 210 Query: 243 KTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTL 289 KT AQ ++R+ +Q+ VV PKSV ER+ EN VFDF+L+ ++ + Sbjct: 211 KTPAQAVLRWHLQKGFVVFPKSVRRERLEENLDVFDFDLTDTEIAAI 257 >3UP8-A nrPDB Length = 298 Score = 166 bits (419), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 95/295 (32%), Positives = 155/295 (52%), Gaps = 39/295 (13%) Query: 8 NNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQV 67 +NGA +P LG GT++ +V + A+ +G+RH+D A +Y NE EVG AIQ+ Sbjct: 29 SNGANIPALGFGTFRMSGAEVLRILPQALKLGFRHVDTAQIYGNEAEVGEAIQKS----G 84 Query: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDE 127 + R ++F+ +K+W + + ++L L+ D++DL L+HWP Sbjct: 85 IPRADVFLTTKVWVDNYRHDAFIASVDESLRKLRTDHVDLLLLHWPG------------- 131 Query: 128 SGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP-AVNQIE 186 SD + + A+ E+ + G V+ IGISNFN Q+E L P A NQ+E Sbjct: 132 ------SDVPMAERIGALNEVRNAGKVRHIGISNFNTTQME---EAARLSDAPIATNQVE 182 Query: 187 CHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTA 246 HPYL Q K++Q + G+ +T+Y + + P DP + I +H KT A Sbjct: 183 YHPYLDQTKVLQTARRLGMSLTSYYAMANGKVP----------ADPLLTEIGGRHGKTAA 232 Query: 247 QVLIRFPM-QRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNR-NWRVC 299 QV +R+ + Q++++V+ K+ T R+ ENF +FDF L+ ++M + R N R+ Sbjct: 233 QVALRWLVQQQDVIVLSKTATEARLKENFAIFDFALTREEMAAVRELARPNGRIV 287 >4H8N-A nrPDB Length = 310 Score = 140 bits (353), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 97/299 (32%), Positives = 158/299 (52%), Gaps = 44/299 (14%) Query: 9 NGAKMPI-LGLGT-WKSP------PGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60 +G ++ I LG GT WK ++ + + + + +G+RHID A Y + EVG Sbjct: 18 SGKEISIALGTGTKWKQAQTINDVSTELVDNILLGLKLGFRHIDTAEAYNTQKEVG---- 73 Query: 61 EKLREQVVKREELFIVSKL---WCTYHEKGLVKG---ACQKTLSDLKLDYLDLYLIHWPT 114 E L+ V RE++++ +K W + K K + K L+ L +DY+DL+LIH P Sbjct: 74 EALKRTDVPREDIWVTTKYSPGWGSI--KAYSKSPSDSIDKALAQLGVDYVDLFLIHSP- 130 Query: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISN--FNHLQVEMILN 172 FF +++ + W A+ E G V+ IGISN HL+ ++ Sbjct: 131 -------FFTTEQTHGYT-----LEQAWEALVEAKKAGKVREIGISNAAIPHLE-KLFAA 177 Query: 173 KPGLKYKPAVNQIECHPYLTQEK--LIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLE 230 P +Y P VNQIE HP+L + ++++CQ GI+V A+SPL P A+ E +L E Sbjct: 178 SPSPEYYPVVNQIEFHPFLQNQSKNIVRFCQEHGILVEAFSPLA----PLARVETNALAE 233 Query: 231 DPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTL 289 +K +A K+ KT AQVL+R+ +QR ++ + S R+ E+ +FDFEL+ +++ + Sbjct: 234 T--LKRLAEKYKKTEAQVLLRYTLQRGILPVTTSSKESRLKESLNLFDFELTDEEVNEI 290 >3WG6-A nrPDB Length = 307 Score = 131 bits (329), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 89/296 (30%), Positives = 145/296 (48%), Gaps = 42/296 (14%) Query: 7 LNNGAKMPILGLGTW--------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVA 58 L+NG K+P + GT Q+ +++A+ G+RHID A +Y E+G+A Sbjct: 13 LSNGNKIPAVAFGTGTKYFKRGHNDLDKQLIGTLELALRSGFRHIDGAEIYGTNKEIGIA 72 Query: 59 IQEKLREQVVKREELFIVSKLWC---TYHEKGLVK----GACQKTLSDLKLDYLDLYLIH 111 L+ + R+++FI K TY K A + L DL L+Y+DLYLIH Sbjct: 73 ----LKNVGLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGLEYVDLYLIH 128 Query: 112 WPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMIL 171 +P + F ++++ W +E +EGL + IG+SNF ++ IL Sbjct: 129 FPYISEKSHGF--------------DLVEAWRYLERAKNEGLARNIGVSNFTIENLKSIL 174 Query: 172 NKPGLKYKPAVNQIECHPYLTQEK--LIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLL 229 + P VNQIE YL + +++Y Q +GI++ AY PLG + P D L Sbjct: 175 D-ANTDSIPVVNQIEFSAYLQDQTPGIVEYSQQQGILIEAYGPLGPITQGRPGPLDKVL- 232 Query: 230 EDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQD 285 ++ K+ + Q+L+R+ +QR ++ I + ERI + ++FDFEL +D Sbjct: 233 -----SKLSEKYKRNEGQILLRWVLQRGILPITTTSKEERINDVLEIFDFELDKED 283 >1PZ1-A nrPDB Length = 333 Score = 70.9 bits (172), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 60/228 (26%), Positives = 98/228 (42%), Gaps = 47/228 (20%) Query: 6 LLNNGAKMPILGLGTWK--------SPPGQVTEAVKVAIDVGYRHIDCAHVY---QNENE 54 + + G + +GLGTW + E ++ A+D G ID A Y Q+E Sbjct: 6 IADTGIEASRIGLGTWAIGGTMWGGTDEKTSIETIRAALDQGITLIDTAPAYGFGQSEEI 65 Query: 55 VGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGA--------CQKTLSDLKLDYLD 106 VG AI+E + KR+++ + +K + L + A + +L L+ DY+D Sbjct: 66 VGKAIKEYM-----KRDQVILATKTALDWKNNQLFRHANRARIVEEVENSLKRLQTDYID 120 Query: 107 LYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQ 166 LY +HWP P++E+ V M+EL D G ++AIG+SNF+ Q Sbjct: 121 LYQVHWP------DPLVPIEETAEV-------------MKELYDAGKIRAIGVSNFSIEQ 161 Query: 167 VEMILN-KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPL 213 ++ P +P N E +E ++ Y + I Y L Sbjct: 162 MDTFRAVAPLHTIQPPYNLFERE---MEESVLPYAKDNKITTLLYGSL 206 >1PYF-A nrPDB Length = 312 Score = 58.5 bits (140), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 70/298 (23%), Positives = 126/298 (42%), Gaps = 73/298 (24%) Query: 30 EAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVK---REELFIVSKLWCTYHEK 86 E V+ AI G +D A++Y G+ E+L +V++ RE++ I +K + ++ Sbjct: 39 ELVREAIRNGVTMLDTAYIY------GIGRSEELIGEVLREFNREDVVIATK--AAHRKQ 90 Query: 87 G----------LVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDT 136 G +K + ++L L DY+DL+ IH+P E P DE+ N Sbjct: 91 GNDFVFDNSPDFLKKSVDESLKRLNTDYIDLFYIHFPD------EHTPKDEAVN------ 138 Query: 137 NILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYL----T 192 A+ E+ G +++IG+SNF+ Q++ NK GL V+ ++ L Sbjct: 139 -------ALNEMKKAGKIRSIGVSNFSLEQLKEA-NKDGL-----VDVLQGEYNLLNREA 185 Query: 193 QEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDP-------------------- 232 ++ Y + I Y PL S ED + E Sbjct: 186 EKTFFPYTKEHNISFIPYFPLVSGLLAGKYTEDTTFPEGDLRNEQEHFKGERFKENIRKV 245 Query: 233 -RIKAIAAKHNKTTAQVLIRFPMQRNL--VVIPKSVTPERIAENFKVFDFELSSQDMT 287 ++ IA KHN +++ + + R ++IP + +++ +N K D LS +D++ Sbjct: 246 NKLAPIAEKHNVDIPHIVLAWYLARPEIDILIPGAKRADQLIDNIKTADVTLSQEDIS 303 >1LQA-A nrPDB Length = 346 Score = 54.7 bits (130), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 48/162 (29%), Positives = 74/162 (45%), Gaps = 20/162 (12%) Query: 70 REELFIVSKLW--CTYHEKGL----------VKGACQKTLSDLKLDYLDLYLIHWPTGFK 117 RE+L I SK+ ++KG+ ++ A +L L+ DYLDLY +HWP + Sbjct: 79 REKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLDLYQVHWPQ--R 136 Query: 118 PGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK 177 P F L S ++LDT A+ E G ++ IG+SN V L+ Sbjct: 137 PTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKH 196 Query: 178 YKPAVNQIECHPYLTQEK-----LIQYCQSKGIVVTAYSPLG 214 P + I+ +PY + L + Q +G+ + AYS LG Sbjct: 197 DLPRIVTIQ-NPYSLLNRSFEVGLAEVSQYEGVELLAYSCLG 237 >1OG6-A nrPDB Length = 298 Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 47/184 (25%), Positives = 78/184 (42%), Gaps = 34/184 (18%) Query: 18 LGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVS 77 L W Q+ ++ +D+G +D A +Y + A E L+ RE + IVS Sbjct: 24 LMDWNMSARQLVSFIEEHLDLGVTTVDHADIYGG-YQCEAAFGEALKLAPHLRERMEIVS 82 Query: 78 K--LWCTYHEKGLVK----------GACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPL 125 K + T E+ ++ + +++L +L D+LDL LIH P PL Sbjct: 83 KCGIATTAREENVIGHYITDRDHIIKSAEQSLINLATDHLDLLLIHRPD---------PL 133 Query: 126 DESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQI 185 ++ V A + L G V+ G+SNF Q ++ ++ L + A NQ+ Sbjct: 134 MDADEVAD----------AFKHLHQSGKVRHFGVSNFTPAQFALLQSR--LPFTLATNQV 181 Query: 186 ECHP 189 E P Sbjct: 182 EISP 185 >4R9O-A nrPDB Length = 301 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 53/213 (24%), Positives = 87/213 (40%), Gaps = 37/213 (17%) Query: 18 LGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVS 77 L W Q+ ++ +D+G +D A +Y + A E L RE+L IV+ Sbjct: 27 LMDWNMSARQLVSFIEEHLDLGVTTVDHADIY-GGYQCEAAFGEALTLAPHLREKLQIVT 85 Query: 78 K------------LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPL 125 K L ++ + + +++L +L DYLD+ LIH P PL Sbjct: 86 KCGIATTARAENKLGHYITDRRHIILSAEQSLKNLATDYLDMLLIHRPD---------PL 136 Query: 126 DESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQI 185 ++ +V A + L G V+ G+SNF Q ++ ++ L + A NQ+ Sbjct: 137 MDADDVA----------EAFQHLHQSGKVRHFGVSNFTPAQFTLLQSR--LPFTLATNQV 184 Query: 186 ECHPY---LTQEKLIQYCQSKGIVVTAYSPLGS 215 E P L + + Q I A+S LG Sbjct: 185 EISPVHQPLLLDGTLDQLQQLRIRPMAWSCLGG 217 >3EB3-A nrPDB Length = 327 Score = 45.4 bits (106), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 41/176 (23%), Positives = 79/176 (44%), Gaps = 32/176 (18%) Query: 4 RLLLNNGAKMPILGLGTWKSPPGQVTEAVK-----VAIDVGYRHIDCAHVYQNENEVGVA 58 R L +G ++ LGLGTW + GQ+T+ + +A D G D A VY + V Sbjct: 6 RNLGKSGLRVSCLGLGTWVTFGGQITDEMAEHLMTLAYDNGINLFDTAEVYA-AGKAEVV 64 Query: 59 IQEKLREQVVKREELFIVSKLWC---TYHEKGLVKG----ACQKTLSDLKLDYLDLYLIH 111 + ++++ +R L I +K++ E+GL + + +L L+L+Y+D+ + Sbjct: 65 LGNIIKKKGWRRSSLVITTKIFAGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFAN 124 Query: 112 WPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167 P P +E T AM ++++G+ G S ++ +++ Sbjct: 125 RPDPNTPMEE-------------------TVRAMTHVINQGMAMYWGTSRWSSMEI 161 >3N6Q-A nrPDB Length = 346 Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 53/238 (22%), Positives = 100/238 (42%), Gaps = 50/238 (21%) Query: 1 MASRLLLNNGAKMPILGLGTWKSPPGQVT------EAVKVAIDVGYRHIDCAHVY----- 49 M R +G ++P L LG W + G V ++ A D+G H D A+ Y Sbjct: 13 MQYRYCGKSGLRLPALSLGLWHN-FGHVNALESQRAILRKAFDLGITHFDLANNYGPPPG 71 Query: 50 QNENEVGVAIQEKLREQVVKREELFIVSK----LW-CTYHEKGLVK---GACQKTLSDLK 101 E G ++E R+EL I +K +W Y G K + ++L + Sbjct: 72 SAEENFGRLLREDF---AAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMG 128 Query: 102 LDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISN 161 L+Y+D++ H V +T + +T +A+ V G +GIS+ Sbjct: 129 LEYVDIFYSH-------------------RVDENTPMEETASALAHAVQSGKALYVGISS 169 Query: 162 FNHLQVEMILNK------PGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPL 213 ++ + + ++ P L ++P+ N + + ++ + L+ Q+ G+ A++PL Sbjct: 170 YSPERTQKMVELLREWKIPLLIHQPSYNLL--NRWVDKSGLLDTLQNNGVGCIAFTPL 225 >4UUD-B nrPDB Length = 864 Score = 32.0 bits (71), Expect = 0.34, Method: Compositional matrix adjust. Identities = 18/76 (23%), Positives = 39/76 (51%), Gaps = 10/76 (13%) Query: 26 GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKR------EELFIVSKL 79 G+ E V + ID+ +++ H E+ +G A ++ Q+ K+ +E+ ++ K Sbjct: 469 GRTKEQVMLLIDIELAYMNTNH----EDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKG 524 Query: 80 WCTYHEKGLVKGACQK 95 W T + G++KG ++ Sbjct: 525 WLTINNIGIMKGGSKE 540 >5NIK-J nrPDB Length = 654 Score = 32.0 bits (71), Expect = 0.34, Method: Compositional matrix adjust. Identities = 25/81 (30%), Positives = 35/81 (43%), Gaps = 7/81 (8%) Query: 38 VGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTL 97 +G +I V + E+G+ + R V ++ I + L C LV GA TL Sbjct: 538 IGVMNIMLVSVTERTREIGIRMAVGARASDVL-QQFLIEAVLVC------LVGGALGITL 590 Query: 98 SDLKLDYLDLYLIHWPTGFKP 118 S L L L+L W GF P Sbjct: 591 SLLIAFTLQLFLPGWEIGFSP 611 >6DLV-b nrPDB Length = 748 Score = 31.2 bits (69), Expect = 0.57, Method: Compositional matrix adjust. Identities = 18/76 (23%), Positives = 39/76 (51%), Gaps = 10/76 (13%) Query: 26 GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKR------EELFIVSKL 79 G+ E V + ID+ +++ H E+ +G A ++ Q+ K+ +E+ ++ K Sbjct: 469 GRTKEQVMLLIDIELAYMNTNH----EDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKG 524 Query: 80 WCTYHEKGLVKGACQK 95 W T + G++KG ++ Sbjct: 525 WLTINNIGIMKGGSKE 540 >5N48-A nrPDB Length = 188 Score = 30.4 bits (67), Expect = 1.2, Method: Compositional matrix adjust. Identities = 19/68 (27%), Positives = 32/68 (47%), Gaps = 2/68 (2%) Query: 10 GAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRH--IDCAHVYQNENEVGVAIQEKLREQV 67 G++ LG KSPPG + V+V +H + HV+QN + + + +E Sbjct: 86 GSQPGEFTLGAIKSPPGPTSTLVRVVSTNYNQHAMVFFKHVFQNREYFHITLYGRTKELT 145 Query: 68 VKREELFI 75 + +E FI Sbjct: 146 SELKENFI 153 >5GZ9-A nrPDB Length = 305 Score = 30.0 bits (66), Expect = 1.3, Method: Compositional matrix adjust. Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 14/87 (16%) Query: 142 WAAMEEL---------VDEGLVKAIGISNFNHLQVEMI-LNKPGLKYKPAVNQIECHPYL 191 W + EEL V EG VK + +S + +V + L + +K + ++ ++ L Sbjct: 26 WLSCEELRTEVRQLKRVGEGAVKRVFLSEWKEHKVALSRLTRLEMK-EDFLHGLQMLKSL 84 Query: 192 TQEK---LIQYCQSKGIVVTAYSPLGS 215 E L+ YC+ G ++T Y PLGS Sbjct: 85 QSEHVVTLVGYCEEDGTILTEYHPLGS 111 >5FI5-A nrPDB Length = 357 Score = 29.3 bits (64), Expect = 2.2, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 25/48 (52%), Gaps = 1/48 (2%) Query: 213 LGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVV 260 LG+P+ P+ P PSLL ++ A + + Q +I F + N+V Sbjct: 274 LGAPEMPFEVPA-PSLLMGGKVMAASTAGSMKEIQEMIEFAAEHNIVA 320 >1M6J-A nrPDB Length = 261 Score = 29.3 bits (64), Expect = 2.6, Method: Compositional matrix adjust. Identities = 20/50 (40%), Positives = 24/50 (48%), Gaps = 5/50 (10%) Query: 27 QVTEAVKVAIDVGYRHIDC-----AHVYQNENEVGVAIQEKLREQVVKRE 71 QV E VKVAID G + I C A N+ E VA Q K + +E Sbjct: 115 QVAEKVKVAIDAGLKVIACIGETEAQRIANQTEEVVAAQLKAINNAISKE 164 >5ZF1-A nrPDB Length = 301 Score = 28.9 bits (63), Expect = 2.8, Method: Compositional matrix adjust. Identities = 10/23 (43%), Positives = 16/23 (69%) Query: 187 CHPYLTQEKLIQYCQSKGIVVTA 209 CH Y ++KL YC++ I++TA Sbjct: 197 CHRYTPKDKLEAYCRNADIIITA 219 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3RX4-A nrPDB 520 e-148 1ZUA-X nrPDB 496 e-141 4JQA-A nrPDB 481 e-136 1Q5M-A nrPDB 479 e-136 5JM5-A nrPDB 477 e-135 2FVL-A nrPDB 475 e-135 1DLA-A nrPDB 473 e-134 3G1R-A nrPDB 464 e-131 2HE8-A nrPDB 461 e-130 1C9W-A nrPDB 459 e-130 1AFS-A nrPDB 457 e-129 1FRB-A nrPDB 455 e-128 5UXF-A nrPDB 455 e-128 2ALR-A nrPDB 454 e-128 3O3R-A nrPDB 452 e-128 4GAC-A nrPDB 450 e-127 1HQT-A nrPDB 450 e-127 4HBK-A nrPDB 422 e-118 3H7U-A nrPDB 388 e-108 5JH1-A nrPDB 386 e-108 5ZCM-A nrPDB 379 e-106 3H7R-A nrPDB 376 e-105 3WCZ-A nrPDB 375 e-104 5Z6T-A nrPDB 374 e-104 1K8C-A nrPDB 371 e-103 1QWK-A nrPDB 361 e-100 4GIE-A nrPDB 359 1e-99 4F40-A nrPDB 358 2e-99 1VBJ-A nrPDB 357 3e-99 2BGQ-A nrPDB 353 5e-98 3KRB-A nrPDB 351 3e-97 1VP5-A nrPDB 350 5e-97 1MZR-A nrPDB 333 6e-92 3D3F-A nrPDB 323 9e-89 4MHB-A nrPDB 321 3e-88 4OTK-A nrPDB 314 3e-86 4IJC-A nrPDB 303 6e-83 1A80-A nrPDB 303 8e-83 3UP8-A nrPDB 295 2e-80 3WG6-A nrPDB 268 2e-72 4H8N-A nrPDB 264 3e-71 1PYF-A nrPDB 189 1e-48 1PZ1-A nrPDB 186 9e-48 4R9O-A nrPDB 173 1e-43 3N6Q-A nrPDB 171 3e-43 1LQA-A nrPDB 168 4e-42 1OG6-A nrPDB 163 6e-41 3EB3-A nrPDB 158 3e-39 Sequences not found previously or not previously below threshold: 2CLP-A nrPDB 78 4e-15 4EXA-A nrPDB 78 5e-15 2BP1-A nrPDB 78 7e-15 1GVE-A nrPDB 77 8e-15 2C91-A nrPDB 71 6e-13 2WK1-A nrPDB 32 0.32 2WUA-A nrPDB 31 0.73 1N7G-A nrPDB 30 1.1 1LQU-A nrPDB 30 1.4 5ZF1-A nrPDB 30 1.4 4WO8-A nrPDB 30 1.7 1JPH-A nrPDB 30 2.0 2PTS-A nrPDB 30 2.1 4EHI-A nrPDB 29 2.4 1TLU-A nrPDB 28 4.8 3EAG-A nrPDB 28 5.1 5C5E-A nrPDB 28 5.2 5FMG-D nrPDB 28 5.3 2EBD-A nrPDB 28 7.4 3Q3N-A nrPDB 28 8.2 >3RX4-A nrPDB Length = 336 Score = 520 bits (1339), Expect = e-148, Method: Composition-based stats. Identities = 316/316 (100%), Positives = 316/316 (100%) Query: 1 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ Sbjct: 21 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 80 Query: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK Sbjct: 81 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 140 Query: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP Sbjct: 141 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 200 Query: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK Sbjct: 201 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 260 Query: 241 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA 300 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA Sbjct: 261 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA 320 Query: 301 LLSCTSHKDYPFHEEF 316 LLSCTSHKDYPFHEEF Sbjct: 321 LLSCTSHKDYPFHEEF 336 >1ZUA-X nrPDB Length = 317 Score = 496 bits (1276), Expect = e-141, Method: Composition-based stats. Identities = 223/316 (70%), Positives = 263/316 (83%) Query: 1 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60 MA+ + L+ AKMPI+GLGTWKSP G+V EAVKVAID GYRHIDCA+VYQNE+EVG AIQ Sbjct: 2 MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 61 Query: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120 EK++E+ VKRE+LFIVSKLW T+ E+ LV+ A +KTL DLKL YLD+YLIHWP GFK G Sbjct: 62 EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 121 Query: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180 + FP D+ GN + LD W AMEELVDEGLVKA+G+SNF+H Q+E +LNKPGLKYKP Sbjct: 122 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 181 Query: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240 NQ+ECHPYLTQEKLIQYC SKGI VTAYSPLGSPDRPWAKPEDPSLLEDP+IK IAAK Sbjct: 182 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 241 Query: 241 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA 300 H KT AQVLIRF +QRN++VIPKSVTP RI EN +VFDF+LS ++M T+LS+NRNWR C Sbjct: 242 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 301 Query: 301 LLSCTSHKDYPFHEEF 316 +L + +DYPF+ E+ Sbjct: 302 VLQSSHLEDYPFNAEY 317 >4JQA-A nrPDB Length = 331 Score = 481 bits (1239), Expect = e-136, Method: Composition-based stats. Identities = 154/318 (48%), Positives = 214/318 (67%), Gaps = 4/318 (1%) Query: 3 SRLLLNNGAKMPILGLGTW---KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI 59 + LN+G MP+LG GT+ + P + EAVK+AI+ G+ HID AHVY NE +VG+AI Sbjct: 6 QCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAI 65 Query: 60 QEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPG 119 + K+ + VKRE++F SKLW H LV+ A +++L +L+LDY+DLYLIH+P KPG Sbjct: 66 RSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125 Query: 120 KEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYK 179 +E P DE+G ++ ++ TW AME+ D GL K+IG+SNFNH +EMILNKPGLKYK Sbjct: 126 EEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYK 185 Query: 180 PAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPD-RPWAKPEDPSLLEDPRIKAIA 238 P NQ+ECHPY Q KL+ +C+SK IV+ AYS LGS PW P P LLEDP + A+A Sbjct: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALA 245 Query: 239 AKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRV 298 KH +T A + +R+ +QR +VV+ KS +RI +N +VF+F+L+S++M + NRN R Sbjct: 246 KKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRY 305 Query: 299 CALLSCTSHKDYPFHEEF 316 L +YPF +E+ Sbjct: 306 LTLDIFAGPPNYPFSDEY 323 >1Q5M-A nrPDB Length = 322 Score = 479 bits (1234), Expect = e-136, Method: Composition-based stats. Identities = 161/318 (50%), Positives = 219/318 (68%), Gaps = 4/318 (1%) Query: 3 SRLLLNNGAKMPILGLGTW---KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI 59 R+ L++G +P+LG GT+ + P + EA K+AID G+RHID A+ Y+NE EVG+AI Sbjct: 5 QRVALSDGHFIPVLGFGTYAPEEVPKSKAMEATKIAIDAGFRHIDSAYFYKNEKEVGLAI 64 Query: 60 QEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPG 119 + K+ + VKRE++F SKLWCT+H LV+ + + +L +L+LDY+DLY+IH+PT KPG Sbjct: 65 RSKIADGTVKREDIFYTSKLWCTFHRPELVRPSLEDSLKNLQLDYVDLYIIHFPTALKPG 124 Query: 120 KEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYK 179 E P DE G + +I TW AME+ D GL K+IG+SNFN Q+EMILNKPGLKYK Sbjct: 125 VEIIPTDEHGKAIFDTVDICATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 184 Query: 180 PAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP-WAKPEDPSLLEDPRIKAIA 238 P NQ+ECHPYL Q KL+++C+SKGIV+ AYS LGS P W P LLEDP I A+A Sbjct: 185 PVCNQVECHPYLNQGKLLEFCKSKGIVLVAYSALGSHREPEWVDQSAPVLLEDPLIGALA 244 Query: 239 AKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRV 298 KH +T A + +R+ +QR +VV+ KS T +RI EN +VF+F+L S+DM + S NRN+R Sbjct: 245 KKHQQTPALIALRYQLQRGIVVLAKSFTEKRIKENIQVFEFQLPSEDMKVIDSLNRNFRY 304 Query: 299 CALLSCTSHKDYPFHEEF 316 H +YPF +E+ Sbjct: 305 VTADFAIGHPNYPFSDEY 322 >5JM5-A nrPDB Length = 332 Score = 477 bits (1227), Expect = e-135, Method: Composition-based stats. Identities = 151/319 (47%), Positives = 213/319 (66%), Gaps = 4/319 (1%) Query: 2 ASRLLLNNGAKMPILGLGTW---KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVA 58 + LN+G MP+LG GT+ + P + E K+AI+ G+RHID AH+Y NE +VG+A Sbjct: 5 QQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLA 64 Query: 59 IQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP 118 I+ K+ + VKRE++F SKLW T+H LV+ A + +L +LDY+DLYLIH P KP Sbjct: 65 IRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKP 124 Query: 119 GKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKY 178 G+E P DE+G V+ ++ TW AME+ D GL K+IG+SNFN Q+EMILNKPGLKY Sbjct: 125 GEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184 Query: 179 KPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP-DRPWAKPEDPSLLEDPRIKAI 237 KP NQ+ECHPY + KL+ +C+SK IV+ AYS LGS D+ W P P LLEDP + A+ Sbjct: 185 KPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCAL 244 Query: 238 AAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR 297 A KH +T A + +R+ +QR +VV+ KS +RI +N +VF+F+L+++DM + +RN Sbjct: 245 AKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLH 304 Query: 298 VCALLSCTSHKDYPFHEEF 316 S SH +YP+ +E+ Sbjct: 305 YFNSDSFASHPNYPYSDEY 323 >2FVL-A nrPDB Length = 324 Score = 475 bits (1224), Expect = e-135, Method: Composition-based stats. Identities = 152/318 (47%), Positives = 217/318 (68%), Gaps = 4/318 (1%) Query: 3 SRLLLNNGAKMPILGLGTW---KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI 59 R+ LN+G MP+LG GT+ + P + E K+AI+ G+RHID A++Y NE +VG+AI Sbjct: 7 QRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAI 66 Query: 60 QEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPG 119 + K+ + VKRE++F SKLWCT+ + +V+ A + +L L+LDY+DLYL+H+P KPG Sbjct: 67 RSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPG 126 Query: 120 KEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYK 179 + P DE+G V+ ++ TW ME+ D GL K+IG+SNFN+ Q+EMILNKPGLKYK Sbjct: 127 ETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPGLKYK 186 Query: 180 PAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPD-RPWAKPEDPSLLEDPRIKAIA 238 P NQ+ECHPYL Q KL+ +C+SK IV+ A+S LG+ + W P P LLEDP + A+A Sbjct: 187 PVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALA 246 Query: 239 AKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRV 298 KH +T A + +R+ +QR +VV+ KS +RI EN +VF+F+L+S+DM L NRN+R Sbjct: 247 KKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRY 306 Query: 299 CALLSCTSHKDYPFHEEF 316 + H DYPF +E+ Sbjct: 307 VVMDFLMDHPDYPFSDEY 324 >1DLA-A nrPDB Length = 314 Score = 473 bits (1218), Expect = e-134, Method: Composition-based stats. Identities = 272/314 (86%), Positives = 294/314 (93%) Query: 3 SRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEK 62 S L+L GAKMPILGLGTWKSPPG+VTEAVKVAID+GYRHIDCAHVYQNENEVG+ +QEK Sbjct: 1 SHLVLYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLGLQEK 60 Query: 63 LREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEF 122 L+ QVVKRE+LFIVSKLWCT HEK LVKGACQ TL DLKLDYLDLYLIHWPTGFKPGK+ Sbjct: 61 LQGQVVKREDLFIVSKLWCTDHEKNLVKGACQTTLRDLKLDYLDLYLIHWPTGFKPGKDP 120 Query: 123 FPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAV 182 FPLD GNVVP +++ ++TW AMEELVDEGLVKAIG+SNFNHLQVE ILNKPGLKYKPAV Sbjct: 121 FPLDGDGNVVPDESDFVETWEAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAV 180 Query: 183 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHN 242 NQIE HPYLTQEKLI+YC+SKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK+N Sbjct: 181 NQIEVHPYLTQEKLIEYCKSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYN 240 Query: 243 KTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALL 302 KTTAQVLIRFPMQRNL+VIPKSVTPERIAENF+VFDFELS +DM TLLSYNRNWRVCAL+ Sbjct: 241 KTTAQVLIRFPMQRNLIVIPKSVTPERIAENFQVFDFELSPEDMNTLLSYNRNWRVCALM 300 Query: 303 SCTSHKDYPFHEEF 316 SC SHKDYPFHEE+ Sbjct: 301 SCASHKDYPFHEEY 314 >3G1R-A nrPDB Length = 346 Score = 464 bits (1193), Expect = e-131, Method: Composition-based stats. Identities = 159/320 (49%), Positives = 222/320 (69%), Gaps = 5/320 (1%) Query: 2 ASRLLLNNGAKMPILGLGTWK----SPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGV 57 + R+ L++G +PI+GLGT+ +P G +VKVAID GYRHID A++YQNE+EVG Sbjct: 27 SHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGE 86 Query: 58 AIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFK 117 AI+EK+ E V+RE++F KLW T H +V+ ++TL L+LDY+DLY+I P FK Sbjct: 87 AIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFK 146 Query: 118 PGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK 177 PG E +P DE+G + +N+ TW AME D GLVK++G+SNFN Q+E+ILNKPGLK Sbjct: 147 PGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLK 206 Query: 178 YKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP-WAKPEDPSLLEDPRIKA 236 +KP NQ+ECHPY TQ KL+++CQ IV+TAYSPLG+ P W P LL+D + + Sbjct: 207 HKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNS 266 Query: 237 IAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNW 296 + ++NKT AQ+++RF +QR +VVIPKS ERI ENF++FDF L+ ++M + + N+N Sbjct: 267 LGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNV 326 Query: 297 RVCALLSCTSHKDYPFHEEF 316 R LL H +YPFH+E+ Sbjct: 327 RFVELLMWRDHPEYPFHDEY 346 >2HE8-A nrPDB Length = 323 Score = 461 bits (1186), Expect = e-130, Method: Composition-based stats. Identities = 144/318 (45%), Positives = 208/318 (65%), Gaps = 4/318 (1%) Query: 3 SRLLLNNGAKMPILGLGT---WKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI 59 ++LN+G +P+LG GT + P + E K+AID G+ H D A VY E+ VG AI Sbjct: 6 HCVILNDGNFIPVLGFGTALPLECPKSKAKELTKIAIDAGFHHFDSASVYNTEDHVGEAI 65 Query: 60 QEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPG 119 + K+ + V+RE++F SK+WCT LV+ + +++L L+ DY+DLYLIH+P KPG Sbjct: 66 RSKIADGTVRREDIFYTSKVWCTSLHPELVRASLERSLQKLQFDYVDLYLIHYPMALKPG 125 Query: 120 KEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYK 179 +E FP+DE G ++ ++ TW AME+ D GL K+IG+SNFN+ Q+EMILNKPGLKYK Sbjct: 126 EENFPVDEHGKLIFDRVDLCATWEAMEKCKDAGLTKSIGVSNFNYRQLEMILNKPGLKYK 185 Query: 180 PAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDR-PWAKPEDPSLLEDPRIKAIA 238 P NQ+ECHPYL Q KL+ +C+SK IV+ AY LG+ W P LL++P + ++A Sbjct: 186 PVCNQVECHPYLNQMKLLDFCKSKDIVLVAYGVLGTQRYGGWVDQNSPVLLDEPVLGSMA 245 Query: 239 AKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRV 298 K+N+T A + +R+ +QR +VV+ S+ ERI EN +VF+F+LSS+DM L NRN R Sbjct: 246 KKYNRTPALIALRYQLQRGIVVLNTSLKEERIKENMQVFEFQLSSEDMKVLDGLNRNMRY 305 Query: 299 CALLSCTSHKDYPFHEEF 316 H ++PF +E+ Sbjct: 306 IPAAIFKGHPNWPFLDEY 323 >1C9W-A nrPDB Length = 315 Score = 459 bits (1182), Expect = e-130, Method: Composition-based stats. Identities = 223/315 (70%), Positives = 263/315 (83%) Query: 2 ASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQE 61 ++ + L+ AKMPI+GLGTW+SPPGQV EAVKVAID GYRHIDCA+ Y NE+EVG AIQE Sbjct: 1 STFVELSTKAKMPIVGLGTWQSPPGQVKEAVKVAIDAGYRHIDCAYAYYNEHEVGEAIQE 60 Query: 62 KLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKE 121 K++E+ V+RE+LFIVSKLW T E+ L+K A QKTL+DLKLDYLDLYLIHWP G +PGKE Sbjct: 61 KIKEKAVRREDLFIVSKLWPTCFERKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKE 120 Query: 122 FFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPA 181 FP D+ GNV+ S LD W MEELVDEGLVKA+G+SNFNH Q+E ILNKPGLK+KP Sbjct: 121 LFPKDDQGNVLTSKITFLDAWEVMEELVDEGLVKALGVSNFNHFQIERILNKPGLKHKPV 180 Query: 182 VNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKH 241 NQ+ECHPYLTQEKLI+YC SKGI VTAYSPLGSP+RPWAKPEDPSLLEDP+IK IAAKH Sbjct: 181 TNQVECHPYLTQEKLIEYCHSKGITVTAYSPLGSPNRPWAKPEDPSLLEDPKIKEIAAKH 240 Query: 242 NKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCAL 301 KT+AQVLIRF +QRN+VVIPKSVTP RI ENF+VFDF+LS Q+M T+L +NRNWR C L Sbjct: 241 KKTSAQVLIRFHIQRNVVVIPKSVTPARIHENFQVFDFQLSDQEMATILGFNRNWRACLL 300 Query: 302 LSCTSHKDYPFHEEF 316 + ++YP+ E+ Sbjct: 301 PETVNMEEYPYDAEY 315 >1AFS-A nrPDB Length = 323 Score = 457 bits (1176), Expect = e-129, Method: Composition-based stats. Identities = 148/319 (46%), Positives = 210/319 (65%), Gaps = 4/319 (1%) Query: 1 MASRLLLNNGAKMPILGLGTW---KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGV 57 ++ R+ LN+G +P+LG GT K +V +A K+AID G+RH D A++Y+ E EVG Sbjct: 4 ISLRVALNDGNFIPVLGFGTTVPEKVAKDEVIKATKIAIDNGFRHFDSAYLYEVEEEVGQ 63 Query: 58 AIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFK 117 AI+ K+ + VKRE++F SKLW T+H LV+ +KTL +LDY+DLY+IH+P + Sbjct: 64 AIRSKIEDGTVKREDIFYTSKLWSTFHRPELVRTCLEKTLKSTQLDYVDLYIIHFPMALQ 123 Query: 118 PGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK 177 PG FFP DE G ++ +I DTW AME+ D GL K+IG+SNFN Q+E ILNKPGLK Sbjct: 124 PGDIFFPRDEHGKLLFETVDICDTWEAMEKCKDAGLAKSIGVSNFNCRQLERILNKPGLK 183 Query: 178 YKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP-DRPWAKPEDPSLLEDPRIKA 236 YKP NQ+ECH YL Q K++ YC+SK I++ +Y LGS D+ W + P LL+DP + A Sbjct: 184 YKPVCNQVECHLYLNQSKMLDYCKSKDIILVSYCTLGSSRDKTWVDQKSPVLLDDPVLCA 243 Query: 237 IAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNW 296 IA K+ +T A V +R+ +QR +V + +S +RI E +VF+F+L+S+DM L NRN+ Sbjct: 244 IAKKYKQTPALVALRYQLQRGVVPLIRSFNAKRIKELTQVFEFQLASEDMKALDGLNRNF 303 Query: 297 RVCALLSCTSHKDYPFHEE 315 R H ++PF +E Sbjct: 304 RYNNAKYFDDHPNHPFTDE 322 >1FRB-A nrPDB Length = 315 Score = 455 bits (1171), Expect = e-128, Method: Composition-based stats. Identities = 221/315 (70%), Positives = 260/315 (82%) Query: 2 ASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQE 61 A+ + L+ AKMPI+GLGTWKSPP QV EAVK AID GYRHIDCA+ Y NENEVG AIQE Sbjct: 1 ATFVELSTKAKMPIVGLGTWKSPPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQE 60 Query: 62 KLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKE 121 K++E+ V+RE+LFIVSKLW T EK L+K A QKTL+DLKLDYLDLYLIHWP G +PGKE Sbjct: 61 KIKEKAVQREDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKE 120 Query: 122 FFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPA 181 FP D+ G ++ S T L+ W MEELVD+GLVKA+G+SNFNH Q+E +LNKPGLK+KP Sbjct: 121 LFPKDDQGRILTSKTTFLEAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPV 180 Query: 182 VNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKH 241 NQ+ECHPYLTQEKLIQYC SKGI VTAYSPLGSPDRP AKPEDPSLLEDP+IK IAAKH Sbjct: 181 TNQVECHPYLTQEKLIQYCHSKGISVTAYSPLGSPDRPSAKPEDPSLLEDPKIKEIAAKH 240 Query: 242 NKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCAL 301 KT+AQVLIRF +QRN+VVIPKSVTP RI EN +VFDF+LS ++M T+LS+NRNWR C L Sbjct: 241 EKTSAQVLIRFHIQRNVVVIPKSVTPSRIQENIQVFDFQLSDEEMATILSFNRNWRACLL 300 Query: 302 LSCTSHKDYPFHEEF 316 + ++YP+ E+ Sbjct: 301 PETVNMEEYPYDAEY 315 >5UXF-A nrPDB Length = 342 Score = 455 bits (1170), Expect = e-128, Method: Composition-based stats. Identities = 146/319 (45%), Positives = 201/319 (63%), Gaps = 4/319 (1%) Query: 2 ASRLLLNNGAKMPILGLGTWK---SPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVA 58 + LN+G +P LG GT+K P + EA +A+DVGYRH+D A+ YQ E E+G A Sbjct: 24 QHCVKLNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQA 83 Query: 59 IQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP 118 IQ + VVKRE+LF+ +KLWCT LVK A +K+L L+LDY+DLY++H+P K Sbjct: 84 IQSAIAAGVVKREDLFVTTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMKS 143 Query: 119 GKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKY 178 G FP++E G + + DTW +EE D GLVK+IG+SNFNH Q+E ILNKPGLKY Sbjct: 144 GDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPGLKY 203 Query: 179 KPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPD-RPWAKPEDPSLLEDPRIKAI 237 KP NQ+ECH YL Q KL+ YC+SK IV+ AY LG+ + W P LL DP + + Sbjct: 204 KPVCNQVECHLYLNQRKLLDYCESKDIVLVAYGALGTQRYKEWVDQNSPVLLNDPVLCDV 263 Query: 238 AAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR 297 A K+ ++ A + +R+ +QR +V + +S + EN +VF F+LS +DM TL N+N+R Sbjct: 264 AKKNKRSPALIALRYLIQRGIVPLAQSFKENEMRENLQVFGFQLSPEDMKTLDGLNKNFR 323 Query: 298 VCALLSCTSHKDYPFHEEF 316 H +YPF EE+ Sbjct: 324 YLPAEFLVDHPEYPFVEEY 342 >2ALR-A nrPDB Length = 324 Score = 454 bits (1168), Expect = e-128, Method: Composition-based stats. Identities = 161/325 (49%), Positives = 224/325 (68%), Gaps = 12/325 (3%) Query: 2 ASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQE 61 AS +LL+ G KMP++GLGTWKS PGQV AVK A+ VGYRHIDCA +Y NE E+G A++E Sbjct: 2 ASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKE 61 Query: 62 KLREQ-VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120 + V REELF+ SKLW T H V+ A +KTL+DL+L+YLDLYL+HWP F+ G Sbjct: 62 DVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD 121 Query: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180 FP + G + T+ +TW A+E LV +GLV+A+G+SNFN Q++ IL+ ++ P Sbjct: 122 NPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR--P 179 Query: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240 AV Q+ECHPYL Q +LI +CQ++G+ VTAYSPLGS DR W P++P LLE+P + A+A K Sbjct: 180 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK 239 Query: 241 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRV-C 299 + ++ AQ+L+R+ +QR ++ IPKS+TP RI +N KVFDF S ++M L + N+NWR Sbjct: 240 YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIV 299 Query: 300 ALLSC--------TSHKDYPFHEEF 316 +L+ H YPF++ + Sbjct: 300 PMLTVDGKRVPRDAGHPLYPFNDPY 324 >3O3R-A nrPDB Length = 316 Score = 452 bits (1164), Expect = e-128, Method: Composition-based stats. Identities = 218/316 (68%), Positives = 254/316 (80%) Query: 1 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60 M + + L AKMP++GLGTWKSPPGQV EAVK AID GYRH DCA+VYQNE+EVG AIQ Sbjct: 1 MTTFVKLRTKAKMPLVGLGTWKSPPGQVKEAVKAAIDAGYRHFDCAYVYQNESEVGEAIQ 60 Query: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120 EK++E+ V+RE+LFIVSKLW T+ EK L+K A QKTLSDLKLDYLDLYLIHWP G + GK Sbjct: 61 EKIKEKAVRREDLFIVSKLWSTFFEKSLMKEAFQKTLSDLKLDYLDLYLIHWPQGLQAGK 120 Query: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180 EF P D G V+ S + LD W MEELVD+GLVKA+G+SNFNH Q+E +LNKPGLK+KP Sbjct: 121 EFLPKDSQGKVLMSKSTFLDAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKP 180 Query: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240 NQ+ECHPYLTQEKLIQYC SKGI V AYSPLGSPDRP+AKPEDP +LE P+IK IAAK Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGIAVIAYSPLGSPDRPYAKPEDPVVLEIPKIKEIAAK 240 Query: 241 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA 300 H KT AQVLIRF +QRN+ VIPKSVT I EN +VFDF+LS +DM +LS NRNWR C Sbjct: 241 HKKTIAQVLIRFHVQRNVAVIPKSVTLSHIKENIQVFDFQLSEEDMAAILSLNRNWRACG 300 Query: 301 LLSCTSHKDYPFHEEF 316 L + +D+PFHEE+ Sbjct: 301 LFVTSDEEDFPFHEEY 316 >4GAC-A nrPDB Length = 324 Score = 450 bits (1159), Expect = e-127, Method: Composition-based stats. Identities = 158/325 (48%), Positives = 219/325 (67%), Gaps = 12/325 (3%) Query: 2 ASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQE 61 AS +LL+ G KMP++GLGTWKS PGQV A+K A+ GYRHIDCA VY NE E+G A++E Sbjct: 2 ASSVLLHTGQKMPLIGLGTWKSEPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKE 61 Query: 62 KLREQ-VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120 + V REELF+ SKLW T H V+ A +KTL+DL+L+YLDLYL+HWP F+ G Sbjct: 62 SVGSGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD 121 Query: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180 FP + G V T+ +TW A+E LV +GLVKA+G+SNFN Q++ +L+ ++ P Sbjct: 122 NPFPKNADGTVRYDSTHYKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVR--P 179 Query: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240 AV Q+ECHPYL Q +LI +C ++G+ VTAYSPLGS DR W P++P LLE+P + A+A K Sbjct: 180 AVLQVECHPYLAQNELIAHCHARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEK 239 Query: 241 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA 300 H ++ AQ+L+R+ +QR ++ IPKS+ P RI +N +VFDF S ++M L + N+NWR Sbjct: 240 HGRSPAQILLRWQVQRKVICIPKSINPSRILQNIQVFDFTFSPEEMKQLDALNKNWRYIV 299 Query: 301 LLSC---------TSHKDYPFHEEF 316 + H YPF++ + Sbjct: 300 PMITVDGKRVPRDAGHPLYPFNDPY 324 >1HQT-A nrPDB Length = 326 Score = 450 bits (1157), Expect = e-127, Method: Composition-based stats. Identities = 159/325 (48%), Positives = 224/325 (68%), Gaps = 12/325 (3%) Query: 2 ASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQE 61 AS +LL+ G KMP++GLGTWKS PGQV A+K A+ VGYRHIDCA ++ NE E+G A+QE Sbjct: 4 ASCVLLHTGQKMPLIGLGTWKSEPGQVKAAIKYALTVGYRHIDCAAIFGNELEIGEALQE 63 Query: 62 KLREQ-VVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120 + V REELF+ SKLW T H V+ A +KTL+DL+L+YLDLYL+HWP F+ G Sbjct: 64 TVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD 123 Query: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180 FP + G + T+ DTW A+E LV +GLV+A+G+SNF+ Q++ +L+ ++ P Sbjct: 124 NPFPKNADGTIRYDATHYKDTWKALEALVAKGLVRALGLSNFSSRQIDDVLSVASVR--P 181 Query: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240 AV Q+ECHPYL Q +LI +CQ++G+ VTAYSPLGS DR W P +P LLE+P ++A+A K Sbjct: 182 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPNEPVLLEEPVVQALAEK 241 Query: 241 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRV-C 299 +N++ AQ+L+R+ +QR ++ IPKSVTP RI +N +VFDF S ++M L + N+N R Sbjct: 242 YNRSPAQILLRWQVQRKVICIPKSVTPSRIPQNIQVFDFTFSPEEMKQLDALNKNLRFIV 301 Query: 300 ALLSC--------TSHKDYPFHEEF 316 +L+ H YPF++ + Sbjct: 302 PMLTVDGKRVPRDAGHPLYPFNDPY 326 >4HBK-A nrPDB Length = 344 Score = 422 bits (1085), Expect = e-118, Method: Composition-based stats. Identities = 157/312 (50%), Positives = 215/312 (68%), Gaps = 5/312 (1%) Query: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64 L +NNG +P++GLGTW SPPG+V AVK A+++GYRH+DCA+VY+NE E+G A++ L Sbjct: 38 LKMNNGRSIPVIGLGTWNSPPGEVGAAVKKALEIGYRHLDCAYVYRNEAEIGEALENALN 97 Query: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124 +KRE++FI SKLW T+ V+ AC++TL +L+L+YLDLYLIHWP K G + FP Sbjct: 98 SLRLKREDIFITSKLWNTFFRPEHVRKACEETLKNLRLNYLDLYLIHWPVPLKHGGDLFP 157 Query: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184 D +G + + DTW ME+LVDEGLVK+IG+SNFN Q++ IL + KPA Q Sbjct: 158 TDSNGQLCLDNVPHEDTWKEMEKLVDEGLVKSIGLSNFNKRQIQNILEH--CRIKPANLQ 215 Query: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKT 244 IE H KL++Y QS G+ VTAY+PLGSP P +LL P + IA +H KT Sbjct: 216 IEIHANFPNIKLVEYAQSVGLTVTAYAPLGSPAHS---PGKVNLLTKPCVLEIAHRHKKT 272 Query: 245 TAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSC 304 AQVL+R+ +QR L+V+PKSVT +RI ENF+VFDF+LS+++M L + + N R LL Sbjct: 273 PAQVLLRYLLQRKLIVVPKSVTFKRIEENFQVFDFQLSNEEMHELNTESLNERQFTLLQM 332 Query: 305 TSHKDYPFHEEF 316 + H++YPF EE+ Sbjct: 333 SGHQEYPFKEEY 344 >3H7U-A nrPDB Length = 335 Score = 388 bits (996), Expect = e-108, Method: Composition-based stats. Identities = 130/311 (41%), Positives = 182/311 (58%), Gaps = 11/311 (3%) Query: 3 SRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEK 62 + LN GAK P +GLGTW++ PG V +AV A+ +GYRHIDCA +Y NE E+G +++ Sbjct: 26 TFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVLKKL 85 Query: 63 LREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEF 122 ++VVKRE+LFI SKLWCT H+ V A +TL DL+L+Y+DLYLIHWP K G Sbjct: 86 FEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKKGSVG 145 Query: 123 FPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAV 182 + +I TW AME L D G +AIG+SNF+ ++ +L + PAV Sbjct: 146 IKPEN-----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELA--RVPPAV 198 Query: 183 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHN 242 NQ+ECHP Q KL ++C+SKG+ ++AYSPLGSP W K + +L++P + +A K Sbjct: 199 NQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD---VLKNPILNMVAEKLG 255 Query: 243 KTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALL 302 K+ AQV +R+ +Q V+PKS RI ENF VFD+ + M + R+ Sbjct: 256 KSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSI-PDYMFAKFAEIEQARLVTGS 314 Query: 303 SCTSHKDYPFH 313 P+ Sbjct: 315 FLVHETLSPYK 325 >5JH1-A nrPDB Length = 309 Score = 386 bits (991), Expect = e-108, Method: Composition-based stats. Identities = 131/314 (41%), Positives = 183/314 (58%), Gaps = 17/314 (5%) Query: 2 ASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQE 61 A +LN GAK+P +GLG+W+S PG V AV A+ GYRHIDCA VY NE E+G+A+++ Sbjct: 1 ARHFVLNTGAKIPSVGLGSWQSDPGVVGNAVYAAVKAGYRHIDCARVYGNEKEIGLALKK 60 Query: 62 KLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKE 121 E VVKRE++FI SKLW +H V A +L+DL+L+YLDLYLIHWP K G Sbjct: 61 LFEEGVVKREDMFITSKLWNDHHAPEDVPEALNDSLNDLQLEYLDLYLIHWPFRVKKGTN 120 Query: 122 FFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPA 181 P + + TW AME+L D G +AIG+SNF+ ++ +L + PA Sbjct: 121 TSPEN------FVTPDFPATWGAMEKLYDAGKARAIGVSNFSSKKLGDLLAVA--RVPPA 172 Query: 182 VNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKH 241 V+Q+ECHP Q KL +CQS G+ +TAYSPLGSP W +L++P I +IA K Sbjct: 173 VDQVECHPGWQQTKLHSFCQSTGVHLTAYSPLGSPGTTWMNGN---VLKEPIIISIAEKL 229 Query: 242 NKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQ------DMTTLLSYNRN 295 KT+AQV +R+ +Q V+PKS ERI +N V+D+ + ++ N Sbjct: 230 GKTSAQVALRWNIQMGHSVLPKSTNEERIKQNLDVYDWSIPDDLLAKFSEIKQARLLRGN 289 Query: 296 WRVCALLSCTSHKD 309 + V +H++ Sbjct: 290 FIVNPESVYKTHEE 303 >5ZCM-A nrPDB Length = 341 Score = 379 bits (974), Expect = e-106, Method: Composition-based stats. Identities = 131/307 (42%), Positives = 182/307 (59%), Gaps = 12/307 (3%) Query: 4 RLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKL 63 + LN+G +MP++G G WK + V AI VGYR D A Y N E+G I L Sbjct: 23 SIKLNSGYEMPLVGFGCWKVDNATCADTVYNAIKVGYRLFDAAMDYGNCKEIGEGINRAL 82 Query: 64 REQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFK--PGKE 121 E +V R+ELFI SKLW +YH+ V+ A +K LSD+KLDY+DL+LIH+P FK P +E Sbjct: 83 DEGLVARDELFITSKLWNSYHDPKNVELALKKVLSDMKLDYIDLFLIHFPIAFKFVPFEE 142 Query: 122 FFP----LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK 177 +P + N D +L+TW AME+L G K+IGISNF+ + +L G + Sbjct: 143 KYPPAFYCGDGDNFHYEDVPLLETWKAMEKLTKGGKAKSIGISNFSAALIYDLLR--GAE 200 Query: 178 YKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPD----RPWAKPEDPSLLEDPR 233 KPAV QIE HPYL Q +LI+Y QS+GI +TAYS G + + P+L E Sbjct: 201 IKPAVLQIEHHPYLQQPRLIEYVQSQGIAITAYSSFGPQSFLELKHSKALDTPTLFEHKT 260 Query: 234 IKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYN 293 I +IA K+ KT AQVL+R+ QR++ +IPKS P+R+ +N +V DF LS +D + + Sbjct: 261 ITSIADKYKKTPAQVLLRWASQRDIAIIPKSNNPDRLLQNLEVNDFNLSKEDFDEISKLD 320 Query: 294 RNWRVCA 300 ++ R Sbjct: 321 QDLRFNN 327 >3H7R-A nrPDB Length = 331 Score = 376 bits (966), Expect = e-105, Method: Composition-based stats. Identities = 126/312 (40%), Positives = 184/312 (58%), Gaps = 16/312 (5%) Query: 3 SRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEK 62 LN GAK+P +GLGT+ V A++ AI +GYRHIDCA +Y NE E+G +++ Sbjct: 26 RFFELNTGAKLPCVGLGTYAM----VATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKKL 81 Query: 63 LREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEF 122 + + VKREELFI SKLW H V A +KTL DL++DY+DLYLIHWP K + Sbjct: 82 IGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKK-ESL 140 Query: 123 FPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAV 182 P E + + +I TW AME L D G +AIG+SNF+ ++ +LN + PAV Sbjct: 141 MPTPE----MLTKPDITSTWKAMEALYDSGKARAIGVSNFSSKKLTDLLNVA--RVTPAV 194 Query: 183 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHN 242 NQ+ECHP Q+ L + C+SKG+ ++ YSPLGS + + + +L++P + +A K Sbjct: 195 NQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLK---VLQNPIVTEVAEKLG 251 Query: 243 KTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALL 302 KTTAQV +R+ +Q V+PKS + R+ EN VFD+ + +D+ T S + C Sbjct: 252 KTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSI-PEDLFTKFSNIPQEKFCRAT 310 Query: 303 SCTSHKDYPFHE 314 H+ + F++ Sbjct: 311 EFA-HETHGFYK 321 >3WCZ-A nrPDB Length = 308 Score = 375 bits (962), Expect = e-104, Method: Composition-based stats. Identities = 121/316 (38%), Positives = 182/316 (57%), Gaps = 19/316 (6%) Query: 2 ASRLLLNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55 A + LN+G +PI+ LGT + +V +AV AI+ GYRHID A VYQ+E +V Sbjct: 5 APCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQV 64 Query: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115 G I E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P Sbjct: 65 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 124 Query: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175 KP P + + L+TW M++ GL ++IG+SNFN Q+ +++ Sbjct: 125 TKPDDS-----------PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 173 Query: 176 LKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIK 235 ++ P +NQIE +P TQE L+ +CQS GI V AYSP G P +DP + Sbjct: 174 IR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLT 231 Query: 236 AIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRN 295 A+A K+ K+ Q+L+R+ + R L+ IPKS +RIA+N +FDF+L+ +++ + +N+N Sbjct: 232 ALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKN 291 Query: 296 WRVCALLSCTSHKDYP 311 RV + + +YP Sbjct: 292 HRVIDISDWKDYPNYP 307 >5Z6T-A nrPDB Length = 343 Score = 374 bits (960), Expect = e-104, Method: Composition-based stats. Identities = 128/306 (41%), Positives = 175/306 (57%), Gaps = 12/306 (3%) Query: 3 SRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEK 62 + LN+G MP +G G WK +E + AI GYR D A Y NE VG +++ Sbjct: 27 PSIKLNSGYDMPAVGFGCWKVDVDTCSEQIYRAIKTGYRLFDGAEDYANEKLVGAGVKKA 86 Query: 63 LREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFK--PGK 120 + E +VKRE+LF+ SKLW YH V+ A +TLSDL++DY+DL+LIH+P FK P + Sbjct: 87 IDEGIVKREDLFLTSKLWNNYHHPDNVEKALNRTLSDLQVDYVDLFLIHFPVTFKFVPLE 146 Query: 121 EFFP----LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176 E +P + N D IL+TW A+E+LV G +++IG+SNF + +L G Sbjct: 147 EKYPPGFYCGKGDNFDYEDVPILETWKALEKLVKAGKIRSIGVSNFPGALLLDLLR--GA 204 Query: 177 KYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPD----RPWAKPEDPSLLEDP 232 KP+V Q+E HPYL Q +LI++ QS+GI VTAYS G L E+ Sbjct: 205 TIKPSVLQVEHHPYLQQPRLIEFAQSRGIAVTAYSSFGPQSFVELNQGRALNTSPLFENE 264 Query: 233 RIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSY 292 IKAIAAKH K+ AQVL+R+ QR + +IPKS T R+ EN V F+L QD + Sbjct: 265 TIKAIAAKHGKSPAQVLLRWSSQRGIAIIPKSNTVPRLLENKDVNSFDLDEQDFADIAKL 324 Query: 293 NRNWRV 298 + N R Sbjct: 325 DINLRF 330 >1K8C-A nrPDB Length = 322 Score = 371 bits (954), Expect = e-103, Method: Composition-based stats. Identities = 129/314 (41%), Positives = 176/314 (56%), Gaps = 12/314 (3%) Query: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64 + L++G MP +G G WK E V AI GYR D A Y NE EVG ++ + Sbjct: 8 IKLSSGHLMPSIGFGCWKLANATAGEQVYQAIKAGYRLFDGAEDYGNEKEVGDGVKRAID 67 Query: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFK--PGKEF 122 E +VKREE+F+ SKLW YH+ V+ A KTL+DLK+DY+DL+LIH+P FK P +E Sbjct: 68 EGLVKREEIFLTSKLWNNYHDPKNVETALNKTLADLKVDYVDLFLIHFPIAFKFVPIEEK 127 Query: 123 FP----LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKY 178 +P + N V D IL+TW A+E+LV G +K+IG+SNF + +L G Sbjct: 128 YPPGFYCGDGNNFVYEDVPILETWKALEKLVAAGKIKSIGVSNFPGALLLDLLR--GATI 185 Query: 179 KPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPD----RPWAKPEDPSLLEDPRI 234 KPAV Q+E HPYL Q KLI++ Q G+ +TAYS G P+L I Sbjct: 186 KPAVLQVEHHPYLQQPKLIEFAQKAGVTITAYSSFGPQSFVEMNQGRALNTPTLFAHDTI 245 Query: 235 KAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNR 294 KAIAAK+NKT A+VL+R+ QR + VIPKS PER+ +N F+L+ +D + + Sbjct: 246 KAIAAKYNKTPAEVLLRWAAQRGIAVIPKSNLPERLVQNRSFNTFDLTKEDFEEIAKLDI 305 Query: 295 NWRVCALLSCTSHK 308 R + Sbjct: 306 GLRFNDPWDWDNIP 319 >1QWK-A nrPDB Length = 317 Score = 361 bits (927), Expect = e-100, Method: Composition-based stats. Identities = 127/324 (39%), Positives = 182/324 (56%), Gaps = 23/324 (7%) Query: 2 ASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQE 61 + + L+NG +MP++GLGTW+S P +V AVK A+ GYR ID A VYQNE +G AI+E Sbjct: 5 TASIKLSNGVEMPVIGLGTWQSSPAEVITAVKTAVKAGYRLIDTASVYQNEEAIGTAIKE 64 Query: 62 KLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKE 121 L E VVKREELFI +K W G ++G +++L L+L+Y+DLYL H P F Sbjct: 65 LLEEGVVKREELFITTKAWTHELAPGKLEGGLRESLKKLQLEYVDLYLAHMPAAFND--- 121 Query: 122 FFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPA 181 D S ++ + + D W + + GL KA+G+SN+N+ Q+ L L P Sbjct: 122 ----DMSEHIA---SPVEDVWRQFDAVYKAGLAKAVGVSNWNNDQISRALA---LGLTPV 171 Query: 182 VN-QIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDR-----PWAKPED----PSLLED 231 N Q+E H Y Q + +C+ I VT+Y+ LGSP R P + D PS L+D Sbjct: 172 HNSQVELHLYFPQHDHVDFCKKHNISVTSYATLGSPGRVNFTLPTGQKLDWAPAPSDLQD 231 Query: 232 PRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLS 291 + A+A K +KT AQVL+R+ + R ++PKS+ RI ENF+VFDF L+ +D+ L Sbjct: 232 QNVLALAEKTHKTPAQVLLRYALDRGCAILPKSIQENRIKENFEVFDFSLTEEDIAKLEE 291 Query: 292 YNRNWRVCALLSCTSHKDYPFHEE 315 + R+ T H + F E Sbjct: 292 SKNSQRLFLQDFMTGHPEDAFAAE 315 >4GIE-A nrPDB Length = 290 Score = 359 bits (921), Expect = 1e-99, Method: Composition-based stats. Identities = 112/298 (37%), Positives = 167/298 (56%), Gaps = 34/298 (11%) Query: 4 RLLLNNGAKMPILGLGTWKSPPG-QVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEK 62 + L+N +MP LGLG W++ G + AV+ AI+ GYRHID A++Y NE VG I+E Sbjct: 15 CVTLHNSVRMPQLGLGVWRAQDGAETANAVRWAIEAGYRHIDTAYIYSNERGVGQGIRE- 73 Query: 63 LREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEF 122 V REE+++ +K+W + A +++ L L+Y+DLYLIHWP K Sbjct: 74 ---SGVPREEVWVTTKVWNSDQGYEKTLAAFERSRELLGLEYIDLYLIHWPGKKK----- 125 Query: 123 FPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAV 182 +DTW A+E+L +E V+AIG+SNF + + K +P V Sbjct: 126 ---------------FVDTWKALEKLYEEKKVRAIGVSNFEPHHLTELFK--SCKIRPMV 168 Query: 183 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHN 242 NQ+E HP Q L ++C+ I +TA+SPLGS E+ +L++ + IA KHN Sbjct: 169 NQVELHPLFQQRTLREFCKQHNIAITAWSPLGSG-------EEAGILKNHVLGEIAKKHN 221 Query: 243 KTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA 300 K+ AQV+IR+ +Q +V IPKS RI ENF V+DF+L+ ++M + N + R+ A Sbjct: 222 KSPAQVVIRWDIQHGIVTIPKSTNKGRIQENFNVWDFKLTEEEMRQIDELNEDKRIGA 279 >4F40-A nrPDB Length = 288 Score = 358 bits (919), Expect = 2e-99, Method: Composition-based stats. Identities = 125/297 (42%), Positives = 171/297 (57%), Gaps = 29/297 (9%) Query: 5 LLLNNGAKMPILGLGTWKSPPGQVTE-AVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKL 63 + L+NG KMP GLG W+SP G+VTE AVK A+ GYRHID A +Y+NE VG ++ Sbjct: 13 VTLSNGVKMPQFGLGVWQSPAGEVTENAVKWALCAGYRHIDTAAIYKNEESVGAGLRA-- 70 Query: 64 REQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFF 123 V RE++FI +KLW T A +++ L +DY+DLYLIHWP GK+ Sbjct: 71 --SGVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWP----RGKDIL 124 Query: 124 PLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVN 183 + LD+W A E+L E V+AIG+SNF+ +E +L P VN Sbjct: 125 SKEGK--------KYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVL--AMCTVTPMVN 174 Query: 184 QIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNK 243 Q+E HP Q L +C +K I V A+SPLG LL +P + AI AK+NK Sbjct: 175 QVELHPLNNQADLRAFCDAKQIKVEAWSPLGQGK----------LLSNPILSAIGAKYNK 224 Query: 244 TTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA 300 T AQV++R+ +Q+NL+ IPKSV ERI EN +FDFEL ++D+ ++ + N N R Sbjct: 225 TAAQVILRWNIQKNLITIPKSVHRERIEENADIFDFELGAEDVMSIDALNTNSRYGP 281 >1VBJ-A nrPDB Length = 281 Score = 357 bits (917), Expect = 3e-99, Method: Composition-based stats. Identities = 121/306 (39%), Positives = 162/306 (52%), Gaps = 37/306 (12%) Query: 1 MASRLLLNNGAKMPILGLGTWKSPPG-QVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI 59 + L L+NG MP+LG G WK G + A AI GYRHID A +Y+NE G AI Sbjct: 8 LTQSLKLSNGVMMPVLGFGMWKLQDGNEAETATMWAIKSGYRHIDTAAIYKNEESAGRAI 67 Query: 60 QEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPG 119 V REELF+ +KLW + A +K++ L L+Y+DLYLIHWP K Sbjct: 68 AS----CGVPREELFVTTKLWNSDQGYESTLSAFEKSIKKLGLEYVDLYLIHWPGKDK-- 121 Query: 120 KEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYK 179 +DTW A E+L + V+AIG+SNF+ +E +L K Sbjct: 122 ------------------FIDTWKAFEKLYADKKVRAIGVSNFHEHHIEELLKH--CKVA 161 Query: 180 PAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAA 239 P VNQIE HP L Q+ L +YC+SK I VTA+SPLG L+ED R+KAI Sbjct: 162 PMVNQIELHPLLNQKALCEYCKSKNIAVTAWSPLGQG----------HLVEDARLKAIGG 211 Query: 240 KHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVC 299 K+ KT AQV++R+ +Q ++ IPKS RI EN +FDFEL+++D+ + N R Sbjct: 212 KYGKTAAQVMLRWEIQAGVITIPKSGNEARIKENGNIFDFELTAEDIQVIDGMNAGHRYG 271 Query: 300 ALLSCT 305 Sbjct: 272 PDPEVF 277 >2BGQ-A nrPDB Length = 344 Score = 353 bits (906), Expect = 5e-98, Method: Composition-based stats. Identities = 120/311 (38%), Positives = 172/311 (55%), Gaps = 17/311 (5%) Query: 2 ASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAI-DVGYRHIDCAHVYQNENEVGVAIQ 60 +L +G MP +GLGTW++ +V+ AI + GYRH+D A Y E EVG ++ Sbjct: 37 QDHFVLKSGHAMPAVGLGTWRA-GSDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLK 95 Query: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120 + E + R++LF+ SK+WCT V+ A + TL DL+LDY+DLY IHWP K G Sbjct: 96 AAM-EAGIDRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLKDGA 154 Query: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180 P E+G V+ ++ W ME LV +GLVK IG+ N+ ++ +L K P Sbjct: 155 HMPP--EAGEVLEF--DMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSA--KIPP 208 Query: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240 AV Q+E HP +K+ + C+ GI +TAYSPLGS ++ +L DP ++ +A K Sbjct: 209 AVCQMEMHPGWKNDKIFEACKKHGIHITAYSPLGSSEK--------NLAHDPVVEKVANK 260 Query: 241 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA 300 NKT QVLI++ +QR VIPKS ERI EN +VF +E+ +D L S RV Sbjct: 261 LNKTPGQVLIKWALQRGTSVIPKSSKDERIKENIQVFGWEIPEEDFKVLCSIKDEKRVLT 320 Query: 301 LLSCTSHKDYP 311 +K + Sbjct: 321 GEELFVNKTHG 331 >3KRB-A nrPDB Length = 334 Score = 351 bits (900), Expect = 3e-97, Method: Composition-based stats. Identities = 127/313 (40%), Positives = 176/313 (56%), Gaps = 21/313 (6%) Query: 14 PILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQ--VVKRE 71 P LG GTW++PP V AV+ A+ GYRHIDCA+VYQNE +G A + ++ +KRE Sbjct: 26 PRLGFGTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKRE 85 Query: 72 ELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK--EFFPLDESG 129 +++I SKLW H LV+ C+KT+SDL++DYLDL+L+HWP F + FP D G Sbjct: 86 DVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEG 145 Query: 130 NVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHP 189 + + DTW AME+LV+EGLVK IG+SN+ + +LN K KP VNQIE HP Sbjct: 146 RAMLEKVPLADTWRAMEQLVEEGLVKHIGVSNYTVPLLADLLNYA--KIKPLVNQIEIHP 203 Query: 190 YLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDP------SLLEDPRIKAIAAKHNK 243 + + +++C GI VTAYSP+G +A P DP +LE +KAIA Sbjct: 204 WHPNDATVKFCLDNGIGVTAYSPMGGS---YADPRDPSGTQKNVILECKTLKAIADAKGT 260 Query: 244 TTAQVLIRFPMQR----NLVVIPKSVTPERIAENFKVFDFELSSQDMTTLL--SYNRNWR 297 + V + + +++ VIPKS TP RI NFK + +LS DM + N+ R Sbjct: 261 SPHCVALAWHVKKWNTSMYSVIPKSQTPARIEANFKCTEVQLSDDDMDAINNIHLNKRIR 320 Query: 298 VCALLSCTSHKDY 310 C + Sbjct: 321 FCDPAIFWKVPLF 333 >1VP5-A nrPDB Length = 298 Score = 350 bits (898), Expect = 5e-97, Method: Composition-based stats. Identities = 111/307 (36%), Positives = 173/307 (56%), Gaps = 36/307 (11%) Query: 3 SRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEK 62 ++ LNNG +MPILG G ++ PP + E V AI VGYR ID A Y NE VG AI+ Sbjct: 16 PKVTLNNGVEMPILGYGVFQIPPEKTEECVYEAIKVGYRLIDTAASYMNEEGVGRAIKRA 75 Query: 63 LREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEF 122 + E +V+REELF+ +KLW + K A +K+L L+L+Y+DLYLIH P G Sbjct: 76 IDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQPFG------- 128 Query: 123 FPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAV 182 ++ W AMEE+ +GLV+AIG+SNF ++ ++ + PAV Sbjct: 129 --------------DVHCAWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVH--HEIVPAV 172 Query: 183 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHN 242 NQIE HP+ +++ I++ ++ I A+ P + ++ ++ +++IA K+ Sbjct: 173 NQIEIHPFYQRQEEIEFMRNYNIQPEAWGPFAEGRK--------NIFQNGVLRSIAEKYG 224 Query: 243 KTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALL 302 KT AQV++R+ Q+ +V IPK+V ER+ EN +FDFEL+ +DM + + + Sbjct: 225 KTVAQVILRWLTQKGIVAIPKTVRRERMKENISIFDFELTQEDMEKIATLDEGQ-----S 279 Query: 303 SCTSHKD 309 + SH+D Sbjct: 280 AFFSHRD 286 >1MZR-A nrPDB Length = 296 Score = 333 bits (854), Expect = 6e-92, Method: Composition-based stats. Identities = 107/302 (35%), Positives = 164/302 (54%), Gaps = 34/302 (11%) Query: 5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 64 + L +G MP LGLG W++ +V A++ A++VGYR ID A Y+NE VG A++ Sbjct: 28 IKLQDGNVMPQLGLGVWQASNEEVITAIQKALEVGYRSIDTAAAYKNEEGVGKALKNA-- 85 Query: 65 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFP 124 V REELFI +KLW H++ + A +L L+LDY+DLYL+HWP Sbjct: 86 --SVNREELFITTKLWNDDHKR--PREALLDSLKKLQLDYIDLYLMHWP----------- 130 Query: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQ 184 VP+ + ++ W M EL EGL+K+IG+ NF ++ ++++ G P +NQ Sbjct: 131 -------VPAIDHYVEAWKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETG--VTPVINQ 181 Query: 185 IECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKT 244 IE HP + Q +L + + I ++SPL + + + I+ +A K+ KT Sbjct: 182 IELHPLMQQRQLHAWNATHKIQTESWSPLAQGGKG--------VFDQKVIRDLADKYGKT 233 Query: 245 TAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSC 304 AQ++IR+ + LVVIPKSVTP RIAENF V+DF L ++ + ++ R+ Sbjct: 234 PAQIVIRWHLDSGLVVIPKSVTPSRIAENFDVWDFRLDKDELGEIAKLDQGKRLGPDPDQ 293 Query: 305 TS 306 Sbjct: 294 FG 295 >3D3F-A nrPDB Length = 275 Score = 323 bits (827), Expect = 9e-89, Method: Composition-based stats. Identities = 124/297 (41%), Positives = 170/297 (57%), Gaps = 37/297 (12%) Query: 5 LLLNNGAKMPILGLGTWKSPPG-QVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKL 63 + L+NG +MP GLG +K G + TE+VK AI GYR ID A +Y+NE VG+ I+E Sbjct: 8 VKLHNGVEMPWFGLGVFKVENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIGIKE-- 65 Query: 64 REQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFF 123 V REELFI SK+W A +K+L L+LDYLDLYLIHWP K Sbjct: 66 --SGVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWPGKDK------ 117 Query: 124 PLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVN 183 DTW A+E+L +G ++AIG+SNF +E +L + KP VN Sbjct: 118 --------------YKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDA--EIKPMVN 161 Query: 184 QIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNK 243 Q+E HP LTQ++L YC+ +GI + A+SPL LL++ + IA KHNK Sbjct: 162 QVEFHPRLTQKELRDYCKGQGIQLEAWSPLMQGQ----------LLDNEVLTQIAEKHNK 211 Query: 244 TTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA 300 + AQV++R+ +Q +V IPKS+ RI EN +FDFELS +DM + + N++ RV Sbjct: 212 SVAQVILRWDLQHGVVTIPKSIKEHRIIENADIFDFELSQEDMDKIDALNKDERVGP 268 >4MHB-A nrPDB Length = 297 Score = 321 bits (822), Expect = 3e-88, Method: Composition-based stats. Identities = 107/306 (34%), Positives = 160/306 (52%), Gaps = 41/306 (13%) Query: 5 LLLNNGAKMPILGLGTWKSPP-GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKL 63 + LNNG MP+LG G ++ + AV AI+ GYR ID A YQNE +VG A L Sbjct: 18 VKLNNGIAMPLLGFGVFQMTNTAECERAVIDAIETGYRLIDTAASYQNETQVGNA----L 73 Query: 64 REQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFF 123 + + R+ELFI +KLW K +++L+ L+LDY+DLYLIH P G Sbjct: 74 KLSGIARDELFITTKLWLQDTYYEGAKAQFERSLNRLQLDYVDLYLIHQPYG-------- 125 Query: 124 PLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVN 183 ++ W AMEEL G ++AIG+SNF+ ++ ++ K PAVN Sbjct: 126 -------------DVHGAWRAMEELHQAGKIRAIGVSNFHPDRLADLM--AFNKIIPAVN 170 Query: 184 QIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNK 243 QIE +P+ Q + + QS+GI A++P L ++P + AI K+ K Sbjct: 171 QIEVNPFNQQLHAVPWMQSRGIQPEAWAPFAEGRNG--------LFQNPVLTAIGEKYGK 222 Query: 244 TTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLS 303 + QV++R+ QR +V + KSV R+ EN + DFELS++DM + + + A + Sbjct: 223 SVGQVVLRWIFQRGIVSLAKSVRKGRMEENINILDFELSAEDMLQIAALD-----TATSA 277 Query: 304 CTSHKD 309 SH+D Sbjct: 278 FFSHRD 283 >4OTK-A nrPDB Length = 318 Score = 314 bits (805), Expect = 3e-86, Method: Composition-based stats. Identities = 108/297 (36%), Positives = 152/297 (51%), Gaps = 34/297 (11%) Query: 2 ASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQE 61 A + LN+ MP+LGLG + + AV A+++G R ID A+ Y NE VG AI Sbjct: 46 APSITLNDEHTMPVLGLGVAELSDDETERAVSAALEIGCRLIDTAYAYGNEAAVGRAI-- 103 Query: 62 KLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKE 121 V REELF+ +KL + AC+ +L L LDY+DLYLIHWP Sbjct: 104 --AASGVAREELFVTTKLATPDQGFTRSQEACRASLDRLGLDYVDLYLIHWP-------- 153 Query: 122 FFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPA 181 P +D W M + EG ++IG+SNF +E +++ PA Sbjct: 154 ----------APPVGKYVDAWGGMIQSRGEGHARSIGVSNFTAENIENLIDLTF--VTPA 201 Query: 182 VNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKH 241 VNQIE HP L Q++L + +V +Y PL LL++P + +IA+++ Sbjct: 202 VNQIELHPLLNQDELRKANAQHTVVTQSYCPLALGR----------LLDNPTVTSIASEY 251 Query: 242 NKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRV 298 KT AQVL+R+ +Q V+ +S PERIA NF VFDFEL+++ M L N RV Sbjct: 252 VKTPAQVLLRWNLQLGNAVVVRSARPERIASNFDVFDFELAAEHMDALGGLNDGTRV 308 >4IJC-A nrPDB Length = 344 Score = 303 bits (776), Expect = 6e-83, Method: Composition-based stats. Identities = 108/322 (33%), Positives = 177/322 (54%), Gaps = 30/322 (9%) Query: 5 LLLNNGAKMPILGLGTWKSPP--GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEK 62 LNNG ++P LGLGT + +AVK AI GYRHID A Y+ E VG AI+E Sbjct: 25 FSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKEL 84 Query: 63 LREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEF 122 L + +KRE+LFI +K+W ++ V + ++L L L+Y+DL L HWP F+ K+ Sbjct: 85 LEDGSIKREDLFITTKVWPVLWDE--VDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDP 142 Query: 123 --------FPLDESGNVVP-SDTNILDTWAAMEELV---DEGLVKAIGISNFNHLQVEMI 170 P+D+SG + +D + L+T+ +E++ ++ V+AIG+SNF+ +E + Sbjct: 143 KGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERL 202 Query: 171 LNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLE 230 + + + KP VNQ+E HP+L Q +L ++C I++TAYSPLGS P L+ Sbjct: 203 IKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN--------LK 252 Query: 231 DPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLL 290 P +K +A K+N T +LI + +++ +VIP+S+ P RI+ + + L+ ++ L Sbjct: 253 IPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFA--SLTKDELQELN 310 Query: 291 SYNRNW--RVCALLSCTSHKDY 310 + + R ++ Sbjct: 311 DFGEKYPVRFIDEPFAAILPEF 332 >1A80-A nrPDB Length = 277 Score = 303 bits (775), Expect = 8e-83, Method: Composition-based stats. Identities = 102/307 (33%), Positives = 153/307 (49%), Gaps = 35/307 (11%) Query: 3 SRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEK 62 ++LN+G +P LG G +K PP AV+ A++VGYRHID A +Y NE V Sbjct: 3 PSIVLNDGNSIPQLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGV----GAA 58 Query: 63 LREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEF 122 + + R++LFI +KLW H+ A ++L+ L LD +DLYL+HWPT Sbjct: 59 IAASGIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPT-------- 110 Query: 123 FPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAV 182 P+ N + W M EL GL ++IG+SN +E I+ G PAV Sbjct: 111 ----------PAADNYVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATG--VVPAV 158 Query: 183 NQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHN 242 NQIE HP Q ++ + + + + ++ PLG L + A AA H Sbjct: 159 NQIELHPAYQQREITDWAAAHDVKIESWGPLGQGKY--------DLFGAEPVTAAAAAHG 210 Query: 243 KTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALL 302 KT AQ ++R+ +Q+ VV PKSV ER+ EN VFDF+L+ ++ + + + Sbjct: 211 KTPAQAVLRWHLQKGFVVFPKSVRRERLEENLDVFDFDLTDTEIAAIDAMDPGD---GSG 267 Query: 303 SCTSHKD 309 ++H D Sbjct: 268 RVSAHPD 274 >3UP8-A nrPDB Length = 298 Score = 295 bits (756), Expect = 2e-80, Method: Composition-based stats. Identities = 93/295 (31%), Positives = 153/295 (51%), Gaps = 37/295 (12%) Query: 8 NNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQV 67 +NGA +P LG GT++ +V + A+ +G+RH+D A +Y NE EVG AIQ+ Sbjct: 29 SNGANIPALGFGTFRMSGAEVLRILPQALKLGFRHVDTAQIYGNEAEVGEAIQK----SG 84 Query: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDE 127 + R ++F+ +K+W + + ++L L+ D++DL L+HWP Sbjct: 85 IPRADVFLTTKVWVDNYRHDAFIASVDESLRKLRTDHVDLLLLHWP-------------- 130 Query: 128 SGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIEC 187 SD + + A+ E+ + G V+ IGISNFN Q+E A NQ+E Sbjct: 131 -----GSDVPMAERIGALNEVRNAGKVRHIGISNFNTTQMEEAARLSDAPI--ATNQVEY 183 Query: 188 HPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQ 247 HPYL Q K++Q + G+ +T+Y + + P DP + I +H KT AQ Sbjct: 184 HPYLDQTKVLQTARRLGMSLTSYYAMANGKVP----------ADPLLTEIGGRHGKTAAQ 233 Query: 248 VLIRFPM-QRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNR-NWRVCA 300 V +R+ + Q++++V+ K+ T R+ ENF +FDF L+ ++M + R N R+ Sbjct: 234 VALRWLVQQQDVIVLSKTATEARLKENFAIFDFALTREEMAAVRELARPNGRIVN 288 >3WG6-A nrPDB Length = 307 Score = 268 bits (686), Expect = 2e-72, Method: Composition-based stats. Identities = 85/309 (27%), Positives = 146/309 (47%), Gaps = 42/309 (13%) Query: 5 LLLNNGAKMPILGLGTW--------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVG 56 L+NG K+P + GT Q+ +++A+ G+RHID A +Y E+G Sbjct: 11 FKLSNGNKIPAVAFGTGTKYFKRGHNDLDKQLIGTLELALRSGFRHIDGAEIYGTNKEIG 70 Query: 57 VAIQEKLREQVVKREELFIVSKLWCTYH-------EKGLVKGACQKTLSDLKLDYLDLYL 109 +A++ + R+++FI K H + A + L DL L+Y+DLYL Sbjct: 71 IALKNV----GLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGLEYVDLYL 126 Query: 110 IHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEM 169 IH+P + F ++++ W +E +EGL + IG+SNF ++ Sbjct: 127 IHFPYISEKSHGF--------------DLVEAWRYLERAKNEGLARNIGVSNFTIENLKS 172 Query: 170 ILNKPGLKYKPAVNQIECHPYLTQE--KLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPS 227 IL+ P VNQIE YL + +++Y Q +GI++ AY PLG + P Sbjct: 173 ILD-ANTDSIPVVNQIEFSAYLQDQTPGIVEYSQQQGILIEAYGPLGPITQGRPGPL--- 228 Query: 228 LLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMT 287 D + ++ K+ + Q+L+R+ +QR ++ I + ERI + ++FDFEL +D Sbjct: 229 ---DKVLSKLSEKYKRNEGQILLRWVLQRGILPITTTSKEERINDVLEIFDFELDKEDED 285 Query: 288 TLLSYNRNW 296 + + Sbjct: 286 QITKVGKEK 294 >4H8N-A nrPDB Length = 310 Score = 264 bits (676), Expect = 3e-71, Method: Composition-based stats. Identities = 94/316 (29%), Positives = 156/316 (49%), Gaps = 40/316 (12%) Query: 8 NNGAKMPI-LGLGT-WKSP------PGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI 59 +G ++ I LG GT WK ++ + + + + +G+RHID A Y + EVG A+ Sbjct: 17 KSGKEISIALGTGTKWKQAQTINDVSTELVDNILLGLKLGFRHIDTAEAYNTQKEVGEAL 76 Query: 60 QEKLREQVVKREELFIVSKL---WCTYHEKGLVKG-ACQKTLSDLKLDYLDLYLIHWPTG 115 + V RE++++ +K W + + K L+ L +DY+DL+LIH P Sbjct: 77 KR----TDVPREDIWVTTKYSPGWGSIKAYSKSPSDSIDKALAQLGVDYVDLFLIHSP-- 130 Query: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNK-P 174 FF +++ + W A+ E G V+ IGISN +E + P Sbjct: 131 ------FFTTEQTHGY-----TLEQAWEALVEAKKAGKVREIGISNAAIPHLEKLFAASP 179 Query: 175 GLKYKPAVNQIECHPYLTQEK--LIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDP 232 +Y P VNQIE HP+L + ++++CQ GI+V A+SPL P A+ E +L E Sbjct: 180 SPEYYPVVNQIEFHPFLQNQSKNIVRFCQEHGILVEAFSPLA----PLARVETNALAE-- 233 Query: 233 RIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSY 292 +K +A K+ KT AQVL+R+ +QR ++ + S R+ E+ +FDFEL+ +++ + Sbjct: 234 TLKRLAEKYKKTEAQVLLRYTLQRGILPVTTSSKESRLKESLNLFDFELTDEEVNEINKI 293 Query: 293 NR--NWRVCALLSCTS 306 +R Sbjct: 294 GDANPYRAFFHEQFKD 309 >1PYF-A nrPDB Length = 312 Score = 189 bits (481), Expect = 1e-48, Method: Composition-based stats. Identities = 73/322 (22%), Positives = 129/322 (40%), Gaps = 74/322 (22%) Query: 16 LGLGT--------WKSPPGQV-TEAVKVAIDVGYRHIDCAHVYQ---NENEVGVAIQEKL 63 +GLGT + + + E V+ AI G +D A++Y +E +G ++E Sbjct: 16 IGLGTNAVGGHNLYPNLNEETGKELVREAIRNGVTMLDTAYIYGIGRSEELIGEVLRE-- 73 Query: 64 REQVVKREELFIVSKLWCT--------YHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115 RE++ I +K + +K + ++L L DY+DL+ IH+P Sbjct: 74 ----FNREDVVIATKAAHRKQGNDFVFDNSPDFLKKSVDESLKRLNTDYIDLFYIHFP-- 127 Query: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175 E P DE+ N A+ E+ G +++IG+SNF+ Q++ NK G Sbjct: 128 ----DEHTPKDEAVN-------------ALNEMKKAGKIRSIGVSNFSLEQLKEA-NKDG 169 Query: 176 LKYKPAVNQIECHPYL--TQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDP- 232 L V Q E + ++ Y + I Y PL S ED + E Sbjct: 170 LVD---VLQGEYNLLNREAEKTFFPYTKEHNISFIPYFPLVSGLLAGKYTEDTTFPEGDL 226 Query: 233 --------------------RIKAIAAKHNKTTAQVLIRFPMQRNL--VVIPKSVTPERI 270 ++ IA KHN +++ + + R ++IP + +++ Sbjct: 227 RNEQEHFKGERFKENIRKVNKLAPIAEKHNVDIPHIVLAWYLARPEIDILIPGAKRADQL 286 Query: 271 AENFKVFDFELSSQDMTTLLSY 292 +N K D LS +D++ + Sbjct: 287 IDNIKTADVTLSQEDISFIDKL 308 >1PZ1-A nrPDB Length = 333 Score = 186 bits (473), Expect = 9e-48, Method: Composition-based stats. Identities = 70/339 (20%), Positives = 128/339 (37%), Gaps = 71/339 (20%) Query: 1 MASRLLLNNGAKMPILGLGTWK--------SPPGQVTEAVKVAIDVGYRHIDCAHVYQ-- 50 M + + G + +GLGTW + E ++ A+D G ID A Y Sbjct: 1 MEYTSIADTGIEASRIGLGTWAIGGTMWGGTDEKTSIETIRAALDQGITLIDTAPAYGFG 60 Query: 51 -NENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGA--------CQKTLSDLK 101 +E VG AI+E + KR+++ + +K + L + A + +L L+ Sbjct: 61 QSEEIVGKAIKEYM-----KRDQVILATKTALDWKNNQLFRHANRARIVEEVENSLKRLQ 115 Query: 102 LDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISN 161 DY+DLY +HWP I +T M+EL D G ++AIG+SN Sbjct: 116 TDYIDLYQVHWPDPL-------------------VPIEETAEVMKELYDAGKIRAIGVSN 156 Query: 162 FNHLQVEMILN-KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPW 220 F+ Q++ P +P N E +E ++ Y + I Y L Sbjct: 157 FSIEQMDTFRAVAPLHTIQPPYNLFERE---MEESVLPYAKDNKITTLLYGSLCRGLLTG 213 Query: 221 AKPEDPSLLEDPR---------------------IKAIAA-KHNKTTAQVLIRFPMQRNL 258 E+ + D + +A ++ K+ + +R+ + + Sbjct: 214 KMTEEYTFEGDDLRNHDPKFQKPRFKEYLSAVNQLDKLAKTRYGKSVIHLAVRWILDQPG 273 Query: 259 VVIP--KSVTPERIAENFKVFDFELSSQDMTTLLSYNRN 295 I + P ++ ++ + L+S+D + + N Sbjct: 274 ADIALWGARKPGQLEALSEITGWTLNSEDQKDINTILEN 312 >4R9O-A nrPDB Length = 301 Score = 173 bits (438), Expect = 1e-43, Method: Composition-based stats. Identities = 63/292 (21%), Positives = 107/292 (36%), Gaps = 43/292 (14%) Query: 18 LGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVS 77 L W Q+ ++ +D+G +D A +Y + A E L RE+L IV+ Sbjct: 27 LMDWNMSARQLVSFIEEHLDLGVTTVDHADIYGG-YQCEAAFGEALTLAPHLREKLQIVT 85 Query: 78 K------------LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPL 125 K L ++ + + +++L +L DYLD+ LIH P Sbjct: 86 KCGIATTARAENKLGHYITDRRHIILSAEQSLKNLATDYLDMLLIHRPDPLMDAD----- 140 Query: 126 DESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQI 185 D A + L G V+ G+SNF Q ++ ++ L + A NQ+ Sbjct: 141 --------------DVAEAFQHLHQSGKVRHFGVSNFTPAQFTLLQSR--LPFTLATNQV 184 Query: 186 ECHPYLT---QEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHN 242 E P + + Q I A+S LG + P E + IA + N Sbjct: 185 EISPVHQPLLLDGTLDQLQQLRIRPMAWSCLGGGRLFNDEAYQPLRQE---LSVIAQELN 241 Query: 243 -KTTAQVLIRFPMQRNLVVIP--KSVTPERIAENFKVFDFELSSQDMTTLLS 291 + QV+ + ++ +P S ER+ + L+ Q + Sbjct: 242 ASSIEQVVYAWILRLPSQPLPIIGSGKIERVRAALEAETLSLTRQQWFRIRK 293 >3N6Q-A nrPDB Length = 346 Score = 171 bits (434), Expect = 3e-43, Method: Composition-based stats. Identities = 60/342 (17%), Positives = 133/342 (38%), Gaps = 75/342 (21%) Query: 1 MASRLLLNNGAKMPILGLGTWKSPP-----GQVTEAVKVAIDVGYRHIDCAHVYQ----- 50 M R +G ++P L LG W + ++ A D+G H D A+ Y Sbjct: 13 MQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGS 72 Query: 51 NENEVGVAIQEKLREQVVKREELFIVSK----LWCTYHEKGLVKG----ACQKTLSDLKL 102 E G ++E R+EL I +K +W + G + + ++L + L Sbjct: 73 AEENFGRLLREDFAA---YRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGL 129 Query: 103 DYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNF 162 +Y+D++ H V +T + +T +A+ V G +GIS++ Sbjct: 130 EYVDIFYSHR-------------------VDENTPMEETASALAHAVQSGKALYVGISSY 170 Query: 163 NHLQVEMILNK------PGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP 216 + + + ++ P L ++P+ N + + ++ + L+ Q+ G+ A++PL Sbjct: 171 SPERTQKMVELLREWKIPLLIHQPSYNLL--NRWVDKSGLLDTLQNNGVGCIAFTPLAQG 228 Query: 217 DRPWAKPE------------------DPSLLEDPRIKAI------AAKHNKTTAQVLIRF 252 P +L + + ++ A + ++ AQ+ + + Sbjct: 229 LLTGKYLNGIPQDSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSW 288 Query: 253 PM--QRNLVVIPKSVTPERIAENFK-VFDFELSSQDMTTLLS 291 + R V+ + E++ EN + + + S++++ + Sbjct: 289 LLKDDRVTSVLIGASRAEQLEENVQALNNLTFSTKELAQIDQ 330 >1LQA-A nrPDB Length = 346 Score = 168 bits (425), Expect = 4e-42, Method: Composition-based stats. Identities = 72/343 (20%), Positives = 129/343 (37%), Gaps = 53/343 (15%) Query: 1 MASRLLLNNGAKMPILGLGTW----KSPPGQVTEAVKVAIDVGYRHIDCAHVY------Q 50 M + ++ ++ LGLGT ++ + A+ G ID A +Y + Sbjct: 1 MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPE 60 Query: 51 NENEVGVAIQEKLREQVVKREELFIVSKLWCTYH------------EKGLVKGACQKTLS 98 + + L + RE+L I SK+ ++ ++ A +L Sbjct: 61 TQGLTETYVGNWLAKHG-SREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLK 119 Query: 99 DLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIG 158 L+ DYLDLY +HWP +P F L S ++LDT A+ E G ++ IG Sbjct: 120 RLQTDYLDLYQVHWPQ--RPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIG 177 Query: 159 ISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEK-----LIQYCQSKGIVVTAYSPL 213 +SN V L+ P + I+ +PY + L + Q +G+ + AYS L Sbjct: 178 VSNETAFGVMRYLHLADKHDLPRIVTIQ-NPYSLLNRSFEVGLAEVSQYEGVELLAYSCL 236 Query: 214 GSPDRPWAKPE--DPSLLEDPRIK------------------AIAAKHNKTTAQVLIRFP 253 G P+ + IA +H AQ+ + F Sbjct: 237 GFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFV 296 Query: 254 MQRNLV--VIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNR 294 ++ V + + T +++ N + ELS + + + ++ Sbjct: 297 RRQPFVASTLLGATTMDQLKTNIESLHLELSEDVLAEIEAVHQ 339 >1OG6-A nrPDB Length = 298 Score = 163 bits (414), Expect = 6e-41, Method: Composition-based stats. Identities = 57/272 (20%), Positives = 101/272 (37%), Gaps = 43/272 (15%) Query: 18 LGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVS 77 L W Q+ ++ +D+G +D A +Y + A E L+ RE + IVS Sbjct: 24 LMDWNMSARQLVSFIEEHLDLGVTTVDHADIYGG-YQCEAAFGEALKLAPHLRERMEIVS 82 Query: 78 K------------LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPL 125 K + ++ + + +++L +L D+LDL LIH P Sbjct: 83 KCGIATTAREENVIGHYITDRDHIIKSAEQSLINLATDHLDLLLIHRPDPLMDAD----- 137 Query: 126 DESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQI 185 + A + L G V+ G+SNF Q ++ ++ L + A NQ+ Sbjct: 138 --------------EVADAFKHLHQSGKVRHFGVSNFTPAQFALLQSR--LPFTLATNQV 181 Query: 186 ECHPYLT---QEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHN 242 E P + + Q + A+S LG P E + +A + N Sbjct: 182 EISPVHQPLLLDGTLDQLQQLRVRPMAWSCLGGGRLFNDDYFQPLRDE---LAVVAEELN 238 Query: 243 K-TTAQVLIRFPMQRNLVVIP--KSVTPERIA 271 + QV+ + ++ +P S ER+ Sbjct: 239 AGSIEQVVNAWVLRLPSQPLPIIGSGKIERVR 270 >3EB3-A nrPDB Length = 327 Score = 158 bits (399), Expect = 3e-39, Method: Composition-based stats. Identities = 67/342 (19%), Positives = 132/342 (38%), Gaps = 66/342 (19%) Query: 3 SRLLLNNGAKMPILGLGTWKSPPGQVTEAVKV-----AIDVGYRHIDCAHVYQNENEVGV 57 R L +G ++ LGLGTW + GQ+T+ + A D G D A VY V Sbjct: 5 YRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEHLMTLAYDNGINLFDTAEVYAAGK-AEV 63 Query: 58 AIQEKLREQVVKREELFIVSKLWC---TYHEKGLVKG----ACQKTLSDLKLDYLDLYLI 110 + ++++ +R L I +K++ E+GL + + +L L+L+Y+D+ Sbjct: 64 VLGNIIKKKGWRRSSLVITTKIFAGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFA 123 Query: 111 HWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMI 170 + P +T + +T AM ++++G+ G S ++ +++ Sbjct: 124 NRPDP-------------------NTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEA 164 Query: 171 LNKPGL--KYKPAVNQIECHPYLTQE---KLIQYCQSKGIVVTAYSPLGSP--------- 216 + P Q E H + ++ +L + G+ +SPL Sbjct: 165 YSVARQFNLIPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSG 224 Query: 217 --------DRPWAKPEDPSLLED--------PRIKAIAAKHNKTTAQVLIRFPMQ-RNL- 258 + + +D L E+ ++AIA + T Q+ I + ++ + Sbjct: 225 IPPYSRASLKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVS 284 Query: 259 VVIPKSVTPERIAENFKVFDF--ELSSQDMTTLLSYNRNWRV 298 V+ + E++ EN +LSS + + S N Sbjct: 285 SVLLGASNAEQLMENIGAIQVLPKLSSSIVHEIDSILGNKPY 326 >2CLP-A nrPDB Length = 347 Score = 78.5 bits (192), Expect = 4e-15, Method: Composition-based stats. Identities = 52/324 (16%), Positives = 103/324 (31%), Gaps = 67/324 (20%) Query: 22 KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSK--- 78 + + ++ G+ ID A VY E + + + I +K Sbjct: 38 RMDAPTSAAVTRAFLERGHTEIDTAFVYS-EGQSETILGGLGLRLGGSDCRVKIDTKAIP 96 Query: 79 LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNI 138 L+ + ++ + +L L+ +DL+ +H P T + Sbjct: 97 LFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPD-------------------HSTPV 137 Query: 139 LDTWAAMEELVDEGLVKAIGISNFNHLQVEMI--LNKPGLKYKPAVNQIECHPYLTQ--E 194 +T A +L EG +G+SN+ +V I L K P V Q + Q Sbjct: 138 EETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVET 197 Query: 195 KLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDP---------------------- 232 +L + G+ A++PL + + P Sbjct: 198 ELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKDGKQPVGRFFGNTWAEMYRNRYWKEHH 257 Query: 233 ------RIKAIAAKHNKTTAQV---LIRF-----PMQ--RNLVVIPKSVTPERIAENFKV 276 KA+ A + + + +R+ +Q VI + E++ +N Sbjct: 258 FEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAA 317 Query: 277 FDFELSSQDMTTLLSYNRNWRVCA 300 E + + ++N+ W + A Sbjct: 318 A--EEGPLEPAVVDAFNQAWHLVA 339 >4EXA-A nrPDB Length = 292 Score = 78.1 bits (191), Expect = 5e-15, Method: Composition-based stats. Identities = 51/264 (19%), Positives = 93/264 (35%), Gaps = 58/264 (21%) Query: 3 SRLLLNNGAKMPILGLGTWK---------------SPPGQVTEAVKVAIDVGYRHIDCAH 47 R L + G + LGLGT K + + + +A D+G ID A Sbjct: 32 HRPLGDTGLAVSPLGLGTVKFGRDQGVKYPSGFTIPDDREAADLLALARDLGINLIDTAP 91 Query: 48 VYQ-NENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLV--------KGACQKTLS 98 Y +E +G ++ +RE IVSK+ + + V + + +++L Sbjct: 92 AYGRSEERLGPLLRG-------QREHWVIVSKVGEEFVDGQSVFDFSAAHTRRSVERSLK 144 Query: 99 DLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIG 158 L+ D ++L L+H D + + ++ + T + L EGL+ A G Sbjct: 145 RLETDRIELVLVH-------------SDGNDLDILENSEVYPT---LAALKREGLIGAYG 188 Query: 159 ISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDR 218 +S L + N E + +I+Y + + L S Sbjct: 189 LSGKTVEGGLRALREGDCAMV-TYNLNER----AERPVIEYAAAHAKGILVKKALASGHA 243 Query: 219 PWAKPEDPS------LLEDPRIKA 236 +DP + + P + A Sbjct: 244 CLGAGQDPVRASFELVFDQPGVAA 267 >2BP1-A nrPDB Length = 360 Score = 77.7 bits (190), Expect = 7e-15, Method: Composition-based stats. Identities = 55/314 (17%), Positives = 106/314 (33%), Gaps = 75/314 (23%) Query: 36 IDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKRE-ELFIVSKL--W-CTYHEKGLVKG 91 ++ G+ +D A +Y + I L + + + I +K W + V+ Sbjct: 65 LERGHTELDTAFMYSDGQS--ETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVRS 122 Query: 92 ACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDE 151 + +L L+ +DL+ +H P T + +T A + L E Sbjct: 123 QLETSLKRLQCPQVDLFYLHAPD-------------------HGTPVEETLHACQRLHQE 163 Query: 152 GLVKAIGISNFNHLQVEMI--LNKPGLKYKPAVNQIECHPYLTQ--EKLIQYCQSKGIVV 207 G +G+SN+ +V I L K P V Q + Q +L + G+ Sbjct: 164 GKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRF 223 Query: 208 TAYSPLGSP---------------------DRPWAKPEDPSLLEDPRIKAIA-------A 239 AY+PL WA+ ++ +AIA A Sbjct: 224 YAYNPLAGGLLTGKYKYEDKDGKQPVGRFFGNSWAETYRNRFWKEHHFEAIALVEKALQA 283 Query: 240 KHNKTTAQV---LIRF-----PMQ--RNLVVIPKSVTPERIAENFKVFDFELSSQ---DM 286 + + V +R+ +Q VI + E++ +N + + + Sbjct: 284 AYGASAPSVTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAA-----TEEGPLEP 338 Query: 287 TTLLSYNRNWRVCA 300 + ++N+ W + A Sbjct: 339 AVVDAFNQAWHLVA 352 >1GVE-A nrPDB Length = 327 Score = 77.3 bits (189), Expect = 8e-15, Method: Composition-based stats. Identities = 55/326 (16%), Positives = 108/326 (33%), Gaps = 71/326 (21%) Query: 22 KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE--NEVGVAIQEKLREQVVKREELFIVSK- 78 + + +V+ + G+ ID A VY N + + L K + I +K Sbjct: 18 RMDVTSSSASVRAFLQRGHTEIDTAFVYANGQSETILGDLGLGLGRSGCK---VKIATKA 74 Query: 79 --LWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDT 136 ++ + V+ + +L L+ +DL+ +H+P T Sbjct: 75 APMFGKTLKPADVRFQLETSLKRLQCPRVDLFYLHFPD-------------------HGT 115 Query: 137 NILDTWAAMEELVDEGLVKAIGISNFNHLQVEMI--LNKPGLKYKPAVNQIECHPYLTQ- 193 I +T A +L EG +G+SN+ +V I L K P V Q + Q Sbjct: 116 PIEETLQACHQLHQEGKFVELGLSNYVSWEVAEICTLCKKNGWIMPTVYQGMYNAITRQV 175 Query: 194 -EKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDP-------------------- 232 +L + G+ A++PL ++P Sbjct: 176 ETELFPCLRHFGLRFYAFNPLAGGLLTGRYKYQDKDGKNPESRFFGNPFSQLYMDRYWKE 235 Query: 233 --------RIKAIAAKHNKTTAQV---LIRF---PMQ----RNLVVIPKSVTPERIAENF 274 KA+ + T + +R+ Q + VI + E++ +N Sbjct: 236 EHFNGIALVEKALKTTYGPTAPSMISAAVRWMYHHSQLKGTQGDAVILGMSSLEQLEQNL 295 Query: 275 KVFDFELSSQDMTTLLSYNRNWRVCA 300 + E + + ++++ W + A Sbjct: 296 AL--VEEGPLEPAVVDAFDQAWNLVA 319 >2C91-A nrPDB Length = 338 Score = 71.1 bits (173), Expect = 6e-13, Method: Composition-based stats. Identities = 59/343 (17%), Positives = 116/343 (33%), Gaps = 85/343 (24%) Query: 14 PILGLGTW----KSPPGQVTEAVKVAIDVGYRHIDCAHVY--QNENEVGVAIQEKLR--E 65 P LGT + +V+ ++ G+ +D A +Y + + L + Sbjct: 17 PATVLGTMEMGRRMDASASAASVRAFLERGHSELDTAFMYCDGQSENILGGLGLGLGSGD 76 Query: 66 QVVKREELFIVSKL--W-CTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEF 122 VK I +K W + ++ + +L L+ +DL+ +H P Sbjct: 77 CTVK-----IATKANPWEGKSLKPDSIRSQLETSLKRLQCPRVDLFYLHAPD-------- 123 Query: 123 FPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMI--LNKPGLKYKP 180 T + +T A +L EG +G+SN+ +V I L K P Sbjct: 124 -----------HSTPVEETLCACHQLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILP 172 Query: 181 AVNQIECHPYLTQ--EKLIQYCQSKGIVVTAYSPLGSP---------------------D 217 V Q + Q +L+ + G+ AY+PL Sbjct: 173 TVYQGMYNATTRQVEAELLPCLRHFGLRFYAYNPLAGGLLTGKYKYEDKDGKQPVGRFFG 232 Query: 218 RPWAKPEDPSLLEDPRIKAIA--AK-----HNKTTAQV---LIRF-----PMQ--RNLVV 260 WA+ ++ +AIA K + ++ +R+ +Q R V Sbjct: 233 NNWAETYRNRFWKEHHFEAIALVEKALQTTYGTNAPRMTSAALRWMYHHSQLQGTRGDAV 292 Query: 261 IPKSVTPERIAENFKVFDFELSSQ---DMTTLLSYNRNWRVCA 300 I + E++ +N + + + + ++++ W + A Sbjct: 293 ILGMSSLEQLEQNLAA-----TEEGPLEPAVVEAFDQAWNMVA 330 >2WK1-A nrPDB Length = 282 Score = 32.2 bits (72), Expect = 0.32, Method: Composition-based stats. Identities = 27/144 (18%), Positives = 49/144 (34%), Gaps = 19/144 (13%) Query: 10 GAKMP--ILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGV-AIQEKLREQ 66 G +P ++ G W+ + + A DV R + A +Q +VG + Sbjct: 103 GNNVPGDLVETGVWRGGACILMRGILRAHDVRDRTVWVADSFQGIPDVGEDGYAGDRKMA 162 Query: 67 VVKREELFIVSKLWCTYHEKGLVKGACQK-TLSDLKLDYLDLYLIHWPTGFKPGKEFFPL 125 + +R + VS + V+ + L D ++ +L P FK P+ Sbjct: 163 LHRRNSVLAVS--------EEEVRRNFRNYDLLDEQVRFL-------PGWFKDTLPTAPI 207 Query: 126 DESGNVVPSDTNILDTWAAMEELV 149 D + TW + L Sbjct: 208 DTLAVLRMDGDLYESTWDTLTNLY 231 >2WUA-A nrPDB Length = 440 Score = 31.1 bits (69), Expect = 0.73, Method: Composition-based stats. Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 1/45 (2%) Query: 205 IVVTAY-SPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQV 248 ++V AY SPL R K P + P +KA+ K N A+V Sbjct: 36 VIVAAYRSPLCKAKRGGLKDTYPDDILAPVLKALIEKTNINPAEV 80 >1N7G-A nrPDB Length = 381 Score = 30.3 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 31/84 (36%), Gaps = 11/84 (13%) Query: 24 PPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTY 83 V E K+A+ G D + Y E +G + +++R F ++ Y Sbjct: 20 ADSTVVEPRKIALITGITGQDGS--YLTEFLLGKGYE---VHGLIRRSSNFNTQRINHIY 74 Query: 84 HEKGLVKGACQKTLSDLKLDYLDL 107 + V A +KL Y DL Sbjct: 75 IDPHNVNKAL------MKLHYADL 92 >1LQU-A nrPDB Length = 456 Score = 29.9 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 39/100 (39%), Gaps = 5/100 (5%) Query: 218 RPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFK-- 275 PW + P+IK+I+ + KT RF VV+ + V P ++E + Sbjct: 44 TPWGLVRSGVAPDHPKIKSISKQFEKTAEDPRFRFF---GNVVVGEHVQPGELSERYDAV 100 Query: 276 VFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPFHEE 315 ++ S M + + + A+ + +P E+ Sbjct: 101 IYAVGAQSDRMLNIPGEDLPGSIAAVDFVGWYNAHPHFEQ 140 >5ZF1-A nrPDB Length = 301 Score = 29.9 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 10/23 (43%), Positives = 16/23 (69%) Query: 187 CHPYLTQEKLIQYCQSKGIVVTA 209 CH Y ++KL YC++ I++TA Sbjct: 197 CHRYTPKDKLEAYCRNADIIITA 219 >4WO8-A nrPDB Length = 716 Score = 29.5 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 20/54 (37%), Gaps = 2/54 (3%) Query: 194 EKLIQYCQSKGIVVTAYSP--LGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTT 245 K +++ + + + P LG+ R + P L P K I KH Sbjct: 251 SKSLKFAFNDRLGFITFCPSNLGTTLRASVHAKIPMLASLPNFKEICEKHGIQP 304 >1JPH-A nrPDB Length = 388 Score = 29.5 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 25/56 (44%), Gaps = 2/56 (3%) Query: 15 ILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKR 70 ++GL W P + E V + + D +Y +E E+G +++ L + R Sbjct: 300 VVGL-DWTVAPKKARECVGKTVTLQGNL-DPCALYASEEEIGQLVKQMLDDFGPHR 353 >2PTS-A nrPDB Length = 462 Score = 29.5 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 20/108 (18%), Positives = 39/108 (36%), Gaps = 16/108 (14%) Query: 97 LSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKA 156 L DL + Y D+ L+ G+ P + + + + ++ G + Sbjct: 154 LKDLAVQYRDIPLL----SRTHGQPATPSTIGKEMANVAYRMERQYRQLNQVEILGKING 209 Query: 157 IGISNFNHL----------QV-EMILNKPGLKYKPAVNQIECHPYLTQ 193 + N+N Q E + G+++ P QIE H Y+ + Sbjct: 210 -AVGNYNAHIAAYPEVDWHQFSEEFVTSLGIQWNPYTTQIEPHDYIAE 256 >4EHI-A nrPDB Length = 534 Score = 29.2 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 10/18 (55%), Positives = 13/18 (72%) Query: 40 YRHIDCAHVYQNENEVGV 57 ++HID VYQN +EVG Sbjct: 383 FKHIDGGFVYQNSDEVGE 400 >1TLU-A nrPDB Length = 130 Score = 28.4 bits (62), Expect = 4.8, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 16/51 (31%), Gaps = 11/51 (21%) Query: 110 IH-WPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGI 159 IH WP + F E +D W A E L K + + Sbjct: 67 IHTWPEYGYAAIDLFTCGED----------VDPWKAFEHLKKALKAKRVHV 107 >3EAG-A nrPDB Length = 326 Score = 28.0 bits (61), Expect = 5.1, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 22/50 (44%) Query: 206 VVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQ 255 VV A LG P + ++L + +A H KTT ++ + ++ Sbjct: 82 VVEAILNLGLPYISGPQWLSENVLHHHWVLGVAGTHGKTTTASMLAWVLE 131 >5C5E-A nrPDB Length = 290 Score = 28.0 bits (61), Expect = 5.2, Method: Composition-based stats. Identities = 39/207 (18%), Positives = 70/207 (33%), Gaps = 39/207 (18%) Query: 10 GAKMPILGLGT--WKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQV 67 G +P + +G + P E + + ++ H+ + Q +V A+ E LR Sbjct: 74 GVVVPAIVVGDRDSEDPDEPAKEQLYHSAEL---HLGIHQLEQLPYQVDAALAEFLRLAP 130 Query: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTL-SDLK--LDYLDLYLIHWPTGFKPGKEFFP 124 V E + L H+ L + Q+ L L+ L YL +Y P F P Sbjct: 131 V--ETMADHIMLMGANHDPEL--SSQQRDLAQRLQERLGYLGVYYKRDPDRFLRN---LP 183 Query: 125 LDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNH-----LQVEMILNKPGLKYK 179 ES + AM+ + I +S F+ ++ +N Sbjct: 184 AYESQKLH----------QAMQTSY-----REIVLSYFSPNSNLNQSIDNFVNMAFFADV 228 Query: 180 PAVNQIECHPYLTQEKLIQYCQSKGIV 206 P +E H L ++ + + Sbjct: 229 PVTKVVEIHMELMD----EFAKKLRVE 251 >5FMG-D nrPDB Length = 241 Score = 28.0 bits (61), Expect = 5.3, Method: Composition-based stats. Identities = 15/44 (34%), Positives = 20/44 (45%) Query: 126 DESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEM 169 D + V D ++L A+E + G AI SNF L VE Sbjct: 4 DRAITVFSPDGHLLQVEHALEAVKKGGCAVAIKSSNFAVLAVEK 47 >2EBD-A nrPDB Length = 309 Score = 27.6 bits (60), Expect = 7.4, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 18/31 (58%), Gaps = 2/31 (6%) Query: 49 YQN--ENEVGVAIQEKLREQVVKREELFIVS 77 Y N + +A+ E ++E VKR +L +++ Sbjct: 264 YGNTSAASIPIALHEAIKEGKVKRGDLILMT 294 >3Q3N-A nrPDB Length = 500 Score = 27.6 bits (60), Expect = 8.2, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 15/30 (50%), Gaps = 3/30 (10%) Query: 83 YHEKGLVKGACQKTLSDLKLD---YLDLYL 109 + G +++L DL LD Y DL+L Sbjct: 292 EFMYEWIIGQFERSLIDLGLDKPWYWDLFL 321 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.143 0.434 Lambda K H 0.267 0.0440 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,078,937 Number of Sequences: 36641 Number of extensions: 610618 Number of successful extensions: 2100 Number of sequences better than 10.0: 69 Number of HSP's better than 10.0 without gapping: 105 Number of HSP's successfully gapped in prelim test: 20 Number of HSP's that attempted gapping in prelim test: 1691 Number of HSP's gapped (non-prelim): 129 length of query: 316 length of database: 10,336,785 effective HSP length: 97 effective length of query: 219 effective length of database: 6,782,608 effective search space: 1485391152 effective search space used: 1485391152 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.2 bits)