BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P15047 (248 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2FWM-X nrPDB 503 e-143 1Q7C-A nrPDB 126 7e-30 3OSU-A nrPDB 124 4e-29 2NM0-A nrPDB 120 4e-28 3WOH-A nrPDB 120 5e-28 2PNF-A nrPDB 119 9e-28 4NBT-A nrPDB 118 2e-27 5CDY-A nrPDB 115 1e-26 2HQ1-A nrPDB 113 1e-25 3LYL-A nrPDB 112 1e-25 4M8S-A nrPDB 111 3e-25 2AG5-A nrPDB 109 1e-24 1K2W-A nrPDB 108 2e-24 3RSH-A nrPDB 108 2e-24 4KMS-A nrPDB 108 2e-24 5ITV-A nrPDB 108 2e-24 5B1Y-A nrPDB 108 3e-24 3FTP-A nrPDB 108 3e-24 2C07-A nrPDB 106 9e-24 3F9I-A nrPDB 106 1e-23 4IIN-A nrPDB 105 2e-23 4JRO-A nrPDB 105 2e-23 4IS3-A nrPDB 105 2e-23 5U9P-A nrPDB 104 3e-23 3EMK-A nrPDB 104 4e-23 5OJG-A nrPDB 103 5e-23 4RZH-A nrPDB 103 6e-23 2UVD-A nrPDB 102 1e-22 4DMM-A nrPDB 102 1e-22 3UF0-A nrPDB 102 2e-22 1NFF-A nrPDB 101 2e-22 4Z9Y-A nrPDB 101 3e-22 5OVJ-A nrPDB 100 4e-22 5OVL-A nrPDB 100 4e-22 1CYD-A nrPDB 100 6e-22 3O4R-A nrPDB 100 6e-22 2CFC-A nrPDB 100 1e-21 1UZM-A nrPDB 99 2e-21 3GRP-A nrPDB 99 2e-21 4K6F-A nrPDB 99 2e-21 6NRP-A nrPDB 98 4e-21 4E6P-A nrPDB 97 5e-21 3WTC-A nrPDB 97 5e-21 4BO1-A nrPDB 97 6e-21 1GEE-A nrPDB 97 7e-21 5VT6-A nrPDB 96 1e-20 3V2G-A nrPDB 96 2e-20 1AE1-A nrPDB 93 1e-19 2CDH-G nrPDB 93 1e-19 3WYE-A nrPDB 92 2e-19 2PH3-A nrPDB 92 3e-19 3AUT-A nrPDB 91 3e-19 4AVY-A nrPDB 91 3e-19 5T5Q-A nrPDB 91 4e-19 3UN1-A nrPDB 91 4e-19 3EZL-A nrPDB 91 4e-19 3D3W-A nrPDB 91 5e-19 2HSD-A nrPDB 89 2e-18 1GEG-A nrPDB 89 2e-18 1O5I-A nrPDB 89 2e-18 3V8B-A nrPDB 88 3e-18 4CQM-B nrPDB 88 3e-18 3OEC-A nrPDB 88 3e-18 2B4Q-A nrPDB 87 7e-18 4NBV-A nrPDB 87 8e-18 4MOW-A nrPDB 86 2e-17 4CQL-A nrPDB 85 4e-17 4RZI-B nrPDB 84 4e-17 1AHH-A nrPDB 84 5e-17 2Q2Q-A nrPDB 84 8e-17 4IIV-A nrPDB 83 1e-16 3R3S-A nrPDB 83 1e-16 6CI9-A nrPDB 83 1e-16 3VZS-A nrPDB 83 1e-16 2ZAT-A nrPDB 82 1e-16 3V2H-A nrPDB 81 3e-16 4EGF-A nrPDB 81 4e-16 1H5Q-A nrPDB 81 5e-16 3OIC-A nrPDB 81 5e-16 5YSS-A nrPDB 80 6e-16 1X1T-A nrPDB 80 7e-16 3W8F-A nrPDB 80 7e-16 1YXM-A nrPDB 80 1e-15 3OML-A nrPDB 79 1e-15 3A28-C nrPDB 79 2e-15 3RWB-A nrPDB 78 3e-15 5IZ4-A nrPDB 77 8e-15 4DBZ-A nrPDB 76 1e-14 4CR6-A nrPDB 75 4e-14 4FC7-A nrPDB 74 5e-14 3U5T-A nrPDB 74 8e-14 3T7C-A nrPDB 74 8e-14 1DOH-A nrPDB 74 8e-14 2GDZ-A nrPDB 73 1e-13 3RKU-A nrPDB 73 1e-13 4HP8-A nrPDB 72 2e-13 2AE2-A nrPDB 71 4e-13 3U4C-A nrPDB 71 4e-13 4GKB-A nrPDB 71 4e-13 2EW8-A nrPDB 69 1e-12 5JS6-A nrPDB 69 2e-12 3UVE-A nrPDB 69 2e-12 3E9N-A nrPDB 67 8e-12 1HXH-A nrPDB 67 8e-12 4TRR-A nrPDB 67 9e-12 2BGM-A nrPDB 66 1e-11 3GDF-A nrPDB 66 2e-11 3PXX-A nrPDB 65 2e-11 1BDB-A nrPDB 65 3e-11 4DRY-A nrPDB 65 3e-11 3ZV3-A nrPDB 65 3e-11 2X9N-A nrPDB 64 4e-11 4RGB-A nrPDB 63 1e-10 5ILO-A nrPDB 63 1e-10 2NWQ-A nrPDB 62 2e-10 2O23-A nrPDB 61 4e-10 5EJ2-A nrPDB 59 1e-09 1E3W-A nrPDB 59 2e-09 3KZV-A nrPDB 59 2e-09 1W73-A nrPDB 57 8e-09 2DKN-A nrPDB 57 8e-09 4M89-A nrPDB 56 1e-08 2YW9-A nrPDB 55 3e-08 1FJH-A nrPDB 54 6e-08 5I9N-A nrPDB 53 1e-07 1P33-A nrPDB 53 1e-07 3U9L-A nrPDB 50 7e-07 5TF4-A nrPDB 50 1e-06 3PPI-A nrPDB 50 1e-06 5O3Z-A nrPDB 50 1e-06 4J3F-A nrPDB 49 1e-06 4DA9-A nrPDB 49 2e-06 2BFA-A nrPDB 48 4e-06 4NR0-A nrPDB 48 4e-06 2QHX-A nrPDB 48 5e-06 3GRK-A nrPDB 47 5e-06 1MG5-A nrPDB 46 2e-05 1B15-A nrPDB 46 2e-05 2P91-A nrPDB 45 2e-05 5KOI-A nrPDB 45 3e-05 5WQO-A nrPDB 44 5e-05 6CGE-A nrPDB 44 5e-05 1A27-A nrPDB 44 5e-05 2NTV-A nrPDB 41 4e-04 5CFZ-A nrPDB 40 8e-04 4JQC-A nrPDB 40 0.001 5YCX-A nrPDB 39 0.002 3OIG-A nrPDB 39 0.002 4HBG-A nrPDB 38 0.003 4ZJU-A nrPDB 38 0.004 3K2E-A nrPDB 36 0.014 5TQV-A nrPDB 36 0.014 4ALL-A nrPDB 35 0.025 4Z3K-A nrPDB 33 0.076 4HWK-A nrPDB 33 0.082 5JY1-A nrPDB 33 0.096 5BP9-A nrPDB 32 0.21 3SC6-A nrPDB 32 0.27 3ORF-A nrPDB 32 0.27 5PGZ-A nrPDB 32 0.29 1SNY-A nrPDB 32 0.32 3N0T-A nrPDB 31 0.47 5LCX-A nrPDB 31 0.58 2YQ5-A nrPDB 30 0.84 4OYR-A nrPDB 30 0.96 1ENP-A nrPDB 30 0.96 2Q1W-A nrPDB 30 1.2 5L51-A nrPDB 29 2.3 3IAU-A nrPDB 28 2.5 3OTH-A nrPDB 28 2.7 3DWF-A nrPDB 28 2.9 4ZZV-A nrPDB 28 4.3 1N5D-A nrPDB 28 4.6 1DIR-A nrPDB 27 6.6 >2FWM-X nrPDB Length = 250 Score = 503 bits (1295), Expect = e-143, Method: Compositional matrix adjust. Identities = 248/248 (100%), Positives = 248/248 (100%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVA 60 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVA Sbjct: 3 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVA 62 Query: 61 QVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRR 120 QVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRR Sbjct: 63 QVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRR 122 Query: 121 QRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTD 180 QRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTD Sbjct: 123 QRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTD 182 Query: 181 MQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVV 240 MQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVV Sbjct: 183 MQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVV 242 Query: 241 DGGSTLGA 248 DGGSTLGA Sbjct: 243 DGGSTLGA 250 >1Q7C-A nrPDB Length = 244 Score = 126 bits (317), Expect = 7e-30, Method: Compositional matrix adjust. Identities = 90/250 (36%), Positives = 128/250 (51%), Gaps = 17/250 (6%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQ----YPFATE---VMDV 53 M+F GK VTGA +GIG A A GAKV G + Q Y A +++V Sbjct: 1 MNFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNV 60 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 D A + V +++ AE +D LVN AGI R ++ E+W N+ F L + Sbjct: 61 TDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFRLSKA 120 Query: 114 TMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 M ++R G I+T+ S G + + A+KA L + S+ E+A G+ NVV+ Sbjct: 121 VMRAMMKKRHGRIITIGSVVGTMGNGGQANFAAAKAGLIGFSKSLAREVASRGITVNVVA 180 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 PG +TDM R L SDD QR G Q +P G++ QEIAN + FLASD A++I Sbjct: 181 PGFIETDMTRAL--SDD---QRA-GILAQ----VPAGRLGGAQEIANAVAFLASDEAAYI 230 Query: 234 TLQDIVVDGG 243 T + + V+GG Sbjct: 231 TGETLHVNGG 240 >3OSU-A nrPDB Length = 246 Score = 124 bits (310), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 86/250 (34%), Positives = 127/250 (50%), Gaps = 23/250 (9%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVM------------DV 53 K+ VTGA +GIG + AL E G V + A ++E+ E + +V Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNV-AVNYAGSKEKAEAVVEEIKAKGVDSFAIQANV 63 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 ADA +V + + ++++ LD LVN AGI R ++ +++W N+ G FN Q+ Sbjct: 64 ADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQK 123 Query: 114 TMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 Q RQR GAI+ ++S G + Y A+KA + L S ELA G+ N V+ Sbjct: 124 ATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAVA 183 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 PG +DM L SD+ +EQ + IPL + + +IANT+ FLASD A +I Sbjct: 184 PGFIVSDMTDAL--SDELKEQMLT--------QIPLARFGQDTDIANTVAFLASDKAKYI 233 Query: 234 TLQDIVVDGG 243 T Q I V+GG Sbjct: 234 TGQTIHVNGG 243 >2NM0-A nrPDB Length = 253 Score = 120 bits (302), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 84/244 (34%), Positives = 123/244 (50%), Gaps = 15/244 (6%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYP--FATEVMDVADAAQVAQVC 63 ++V VTG +GIG A A AF +AG KV + + P F D+ D QV Q Sbjct: 22 RSVLVTGGNRGIGLAIARAFADAGDKVA---ITYRSGEPPEGFLAVKCDITDTEQVEQAY 78 Query: 64 QRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRG 123 + + ++ L+ AG+ + ++S+ED+ N+ G F + ++ R + Sbjct: 79 KEIEETHGPVEVLIANAGVTKDQLLMRMSEEDFTSVVETNLTGTFRVVKRANRAMLRAKK 138 Query: 124 GAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQR 183 G +V ++S G + Y ASKA L A S+ EL + NVV+PG DTDM + Sbjct: 139 GRVVLISSVVGLLGSAGQANYAASKAGLVGFARSLARELGSRNITFNVVAPGFVDTDMTK 198 Query: 184 TLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDGG 243 L +EQR + +PLG+ ARP+EIA T+ FLASD AS+IT I VDGG Sbjct: 199 VL-----TDEQRANIVSQ-----VPLGRYARPEEIAATVRFLASDDASYITGAVIPVDGG 248 Query: 244 STLG 247 +G Sbjct: 249 LGMG 252 >3WOH-A nrPDB Length = 251 Score = 120 bits (301), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 84/255 (32%), Positives = 123/255 (48%), Gaps = 23/255 (9%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKV----TGFDQAFTQEQYPFA-------TEVM 51 SGK VTG +G+G A AL GA V D + + Q + Sbjct: 9 LSGKVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLGGTARSYRC 68 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 DV+DA QV + + + A+ +D LVN AGI+R G + ED+ N+ GAF Sbjct: 69 DVSDAEQVTRCVKAVTADLGPVDILVNNAGIIRDGLAASIKDEDYDAVMNTNLKGAFLFI 128 Query: 112 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 171 + F R+R G+I+ ++S + G + Y ++KA L L S+ ELA VRCN Sbjct: 129 KACYFGFIRKRSGSIINISSVSGVFGSAGQANYASAKAGLIGLTKSIAKELAERNVRCNA 188 Query: 172 VSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLAS 231 V+PG TDM + L DD++ +P+ + RP E+A + FLA D +S Sbjct: 189 VAPGLIATDMTQDLV--DDSKRLDP----------VPMRRFGRPDEVAGLVAFLAGDESS 236 Query: 232 HITLQDIVVDGGSTL 246 +IT Q + VDGG + Sbjct: 237 YITGQVVCVDGGMAM 251 >2PNF-A nrPDB Length = 248 Score = 119 bits (299), Expect = 9e-28, Method: Compositional matrix adjust. Identities = 84/254 (33%), Positives = 129/254 (50%), Gaps = 21/254 (8%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKV--TGFD----QAFTQE---QYPFATE-- 49 + GK VTG+ +GIG A A AG+ V TG +A +E +Y Sbjct: 3 IKLQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGV 62 Query: 50 VMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 M++ + + + + + +D LVN AGI R ++S DW++ VN+ G F Sbjct: 63 EMNLLSEESINKAFEEIYNLVDGIDILVNNAGITRDKLFLRMSLLDWEEVLKVNLTGTFL 122 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 + Q ++ + +QR G IV ++S T +G Y +KA L S+ ELA V Sbjct: 123 VTQNSLRKMIKQRWGRIVNISSVVGFTGNVGQVNYSTTKAGLIGFTKSLAKELAPRNVLV 182 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N V+PG +TDM L +EE + +++K IPLG+ P+E+AN +LFL S+L Sbjct: 183 NAVAPGFIETDMTAVL-----SEEIK-----QKYKEQIPLGRFGSPEEVANVVLFLCSEL 232 Query: 230 ASHITLQDIVVDGG 243 AS+IT + I V+GG Sbjct: 233 ASYITGEVIHVNGG 246 >4NBT-A nrPDB Length = 240 Score = 118 bits (296), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 82/247 (33%), Positives = 126/247 (51%), Gaps = 13/247 (5%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV-MDVADAAQVAQ 61 GK +TG KG+G A ALA+ E GAKV D +P + ++V D V + Sbjct: 4 LEGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDLGDLTYSHPNVEGMYLNVTDVTGVEK 63 Query: 62 VCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQ 121 Q ++ + ++D LVN AGI + T ++++ W VN+ G FNL + Q + Sbjct: 64 FYQSVIDKYGKIDILVNNAGITKDAMTRKMTEAQWDAVIDVNLKGVFNLTRLVGPQMQTN 123 Query: 122 RGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELA--GSGVRCNVVSPGSTDT 179 G+I+ ++S IG + Y A+KA + L ++ E A G+ VR N ++PG T Sbjct: 124 GYGSIINISSVVGVFGNIGQANYAATKAGVIGLTMTWAKEFALKGANVRVNAIAPGYIMT 183 Query: 180 DMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIV 239 D+ +T V D ++F L ++ +P+EIA LFLASD AS++T Q I Sbjct: 184 DILKT--VPQD--------LLDKFAALTMLNRLGQPEEIAKVALFLASDDASYVTGQTIN 233 Query: 240 VDGGSTL 246 V+GG L Sbjct: 234 VNGGMRL 240 >5CDY-A nrPDB Length = 244 Score = 115 bits (289), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 87/253 (34%), Positives = 125/253 (49%), Gaps = 23/253 (9%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATE----------V 50 M F GK VTGA +GIG A A VE GA V G T E+ A + Sbjct: 1 MSFEGKIALVTGASRGIGRAIAELLVERGACVIG---TATSEKGAEAISAYLGENGKGLM 57 Query: 51 MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 ++V D + V + AE +D LVN AGI R ++ ++WQ N+ F L Sbjct: 58 LNVVDPTSIDTVLATIRAEFGEVDILVNNAGITRDNLLMRMKDDEWQDIIDTNLTSVFRL 117 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 + M ++R G I+T+ S G Y A+KA + + S+ E+A G+ N Sbjct: 118 SKAVMRAMMKKRFGRIITIGSVVGTMGNAGQVNYAAAKAGVIGFSKSLAREVASRGITVN 177 Query: 171 VVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 230 VV+PG +TDM RTL +DD QR G Q +P ++ +EIA+ + FLASD A Sbjct: 178 VVAPGFIETDMTRTL--TDD---QR-AGILAQ----VPANRLGDAKEIASAVAFLASDEA 227 Query: 231 SHITLQDIVVDGG 243 S+I+ + + V+GG Sbjct: 228 SYISGETLHVNGG 240 >2HQ1-A nrPDB Length = 247 Score = 113 bits (282), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 81/256 (31%), Positives = 118/256 (46%), Gaps = 25/256 (9%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKV--------TGFDQAFTQEQYPFA-TEVM 51 M GK VTG+ +G+G A A GA + T D T E++ A V+ Sbjct: 1 MQLKGKTAIVTGSSRGLGKAIAWKLGNMGANIVLNGSPASTSLDA--TAEEFKAAGINVV 58 Query: 52 ----DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGA 107 DV + V + + + R+D LVN AGI R ++S++DW N+ A Sbjct: 59 VAKGDVKNPEDVENMVKTAMDAFGRIDILVNNAGITRDTLMLKMSEKDWDDVLNTNLKSA 118 Query: 108 FNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGV 167 + + +Q+ G I+ + S A G + Y ASKA L S+ E A G+ Sbjct: 119 YLCTKAVSKIMLKQKSGKIINITSIAGIIGNAGQANYAASKAGLIGFTKSIAKEFAAKGI 178 Query: 168 RCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLAS 227 CN V+PG TDM L D +E + IPL + P+E+AN + FLAS Sbjct: 179 YCNAVAPGIIKTDMTDVL--PDKVKEMYLN--------NIPLKRFGTPEEVANVVGFLAS 228 Query: 228 DLASHITLQDIVVDGG 243 D +++IT Q I +DGG Sbjct: 229 DDSNYITGQVINIDGG 244 >3LYL-A nrPDB Length = 247 Score = 112 bits (281), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 74/253 (29%), Positives = 122/253 (48%), Gaps = 20/253 (7%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTG----------FDQAFTQEQYPFATEV 50 M + K VTGA +GIG+ A A GA V G F+ + ++ + V Sbjct: 1 MSLNEKVALVTGASRGIGFEVAHALASKGATVVGTATSQASAEKFENSMKEKGFKARGLV 60 Query: 51 MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 ++++D + + AE +D LVN AGI R ++S+++WQ N+ F + Sbjct: 61 LNISDIESIQNFFAEIKAENLAIDILVNNAGITRDNLMMRMSEDEWQSVINTNLSSIFRM 120 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 ++ + ++R G I+++ S G + Y A+KA + + S+ E+A + N Sbjct: 121 SKECVRGMMKKRWGRIISIGSVVGSAGNPGQTNYCAAKAGVIGFSKSLAYEVASRNITVN 180 Query: 171 VVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 230 VV+PG TDM L +EQ+ IP G+I P++IA + FLAS+ A Sbjct: 181 VVAPGFIATDMTDKL-----TDEQK-----SFIATKIPSGQIGEPKDIAAAVAFLASEEA 230 Query: 231 SHITLQDIVVDGG 243 +IT Q + V+GG Sbjct: 231 KYITGQTLHVNGG 243 >4M8S-A nrPDB Length = 248 Score = 111 bits (278), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 86/254 (33%), Positives = 123/254 (48%), Gaps = 26/254 (10%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQ------AFTQE--QYPFATEVMDV 53 D SGK VTGA +GIG A A AGAKV G A ++ Q+ V++ Sbjct: 5 DLSGKIALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGGEGRVLNS 64 Query: 54 ADAAQVAQVCQRLLAETER----LDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 A+ + + L+A+ E+ LD LVN AGI R ++ +E+W VN+ F Sbjct: 65 AEP----ETVENLIADIEKTFGKLDILVNNAGITRDNLLMRMKEEEWDDIMQVNLKSVFR 120 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 + + +QR G I+ + S G + Y A+KA L + S+ E+ G+ Sbjct: 121 ASKAVLRGMMKQRAGRIINITSVVGVMGNAGQTNYAAAKAGLIGFSKSMAREVGSRGITV 180 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N V+PG DTDM R L EE R + F LG+ Q+IA+ +LFLASD Sbjct: 181 NCVAPGFIDTDMTRAL-----PEETR-----QTFTAQTALGRFGDAQDIADAVLFLASDQ 230 Query: 230 ASHITLQDIVVDGG 243 A +IT Q + V+GG Sbjct: 231 AKYITGQTLHVNGG 244 >2AG5-A nrPDB Length = 246 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 82/252 (32%), Positives = 127/252 (50%), Gaps = 16/252 (6%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKV--TGFDQAFTQE--QYP-FATEVMDVADAA 57 GK + +T A +GIG A ALAF GAKV T +++ QE +YP T V+DV Sbjct: 4 LDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKK 63 Query: 58 QVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQ 117 Q+ Q E ERLD L N AG + G ++DW + +NV + + + + + Sbjct: 64 QIDQFAN----EVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPK 119 Query: 118 FRRQRGGAIVTVASDAAHTP-RIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGS 176 Q+ G I+ ++S A+ + Y +KAA+ L SV + G+RCN V PG+ Sbjct: 120 MLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGT 179 Query: 177 TDT-DMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITL 235 DT +Q + + EE R Q G+ A +EIA ++LASD ++++T Sbjct: 180 VDTPSLQERIQARGNPEEARNDFLKRQ-----KTGRFATAEEIAMLCVYLASDESAYVTG 234 Query: 236 QDIVVDGGSTLG 247 +++DGG +LG Sbjct: 235 NPVIIDGGWSLG 246 >1K2W-A nrPDB Length = 256 Score = 108 bits (270), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 81/257 (31%), Positives = 123/257 (47%), Gaps = 17/257 (6%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD------QAFTQEQYPFATEV-MDV 53 M GK +TG+ +GIG A A A+V GA+V D +A E P A + +DV Sbjct: 1 MRLDGKTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAAEIGPAACAIALDV 60 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 D A + + LL +D LVN A + + ++++E + + FA+NV G + Q Sbjct: 61 TDQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGTLFMMQA 120 Query: 114 TMN-QFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVV 172 RGG I+ +AS A + Y A+KAA+ SL S GL L G+ N + Sbjct: 121 VARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNLIRHGINVNAI 180 Query: 173 SPGSTDTDMQRTLWVSDDAE----EQRIRGFGE-QFKLGIPLGKIARPQEIANTILFLAS 227 +PG D + W DA+ E RG + Q +P G++ R +++ +FLA+ Sbjct: 181 APGVVDGEH----WDGVDAKFADYENLPRGEKKRQVGAAVPFGRMGRAEDLTGMAIFLAT 236 Query: 228 DLASHITLQDIVVDGGS 244 A +I Q VDGG+ Sbjct: 237 PEADYIVAQTYNVDGGN 253 >3RSH-A nrPDB Length = 251 Score = 108 bits (270), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 77/250 (30%), Positives = 121/250 (48%), Gaps = 17/250 (6%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGF--DQAFTQEQYPFATE-----VMDV 53 M+ GK VTGA +GIG A A E GAKV G ++ Q + + ++V Sbjct: 8 MNLEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMALNV 67 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 + + V + + E +D LVN AGI R ++ +E+W N+ F L + Sbjct: 68 TNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFRLSKA 127 Query: 114 TMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 + ++R G I+ V S G + Y A+KA + S+ E+A GV N V+ Sbjct: 128 VLRGMMKKRQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVASRGVTVNTVA 187 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 PG +TDM + L +EQR + +P G++ P+EIA+ + FLAS A++I Sbjct: 188 PGFIETDMTKAL-----NDEQRTATLAQ-----VPAGRLGDPREIASAVAFLASPEAAYI 237 Query: 234 TLQDIVVDGG 243 T + + V+GG Sbjct: 238 TGETLHVNGG 247 >4KMS-A nrPDB Length = 249 Score = 108 bits (270), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 73/244 (29%), Positives = 117/244 (47%), Gaps = 17/244 (6%) Query: 10 VTGAGKGIGYATALAFVEAGAKV-----TGFDQAF-TQEQYPFATEVMDVADAAQVAQVC 63 VTG +GIG ATAL G V + +D A +E+Y T+ +VAD + Q Sbjct: 15 VTGGTRGIGKATALELKNKGLTVVANFFSNYDAAKEMEEKYGIKTKCWNVADFEECRQAV 74 Query: 64 QRLLAETER-LDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQR 122 + + E ++ + LVN AGI + ++S +DW VN+ FN+ M Q R Q Sbjct: 75 KEIEEEFKKPVSILVNNAGITKDKMLHRMSHQDWNDVINVNLNSCFNMSSSVMEQMRNQD 134 Query: 123 GGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQ 182 G IV ++S A ++G + Y A+KA + ++ E A + N ++PG T+M Sbjct: 135 YGRIVNISSINAQAGQVGQTNYSAAKAGIIGFTKALARETASKNITVNCIAPGYIATEMV 194 Query: 183 RTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDG 242 V +D + I IP ++ +P+EIA + FL + A IT + I ++G Sbjct: 195 GA--VPEDVLAKIIN--------SIPKKRLGQPEEIARAVAFLVDENAGFITGETISING 244 Query: 243 GSTL 246 G + Sbjct: 245 GHNM 248 >5ITV-A nrPDB Length = 255 Score = 108 bits (270), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 75/256 (29%), Positives = 121/256 (47%), Gaps = 16/256 (6%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFV--EAGAKVTGFDQA--------FTQEQYPFATEV 50 M+ + K V +TG GIGYA AF+ +A V D+A ++ F Sbjct: 3 MNLTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRKENNDRLHFVQ-- 60 Query: 51 MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 D+ D A + + LD L+N AGI + ++ DW + VN+ G F + Sbjct: 61 TDITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLM 120 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 + + G I+ S + AY ASK + L S+ ++ A +R N Sbjct: 121 SKHALKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIRVN 180 Query: 171 VVSPGSTDTDM-QRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 V PG DT + +++ +++ + I+ E+ K+ PL ++ +P+EIAN +LFLASDL Sbjct: 181 CVCPGIIDTPLNEKSFLENNEGTLEEIK--KEKAKVN-PLLRLGKPEEIANVMLFLASDL 237 Query: 230 ASHITLQDIVVDGGST 245 +S++T I DGG T Sbjct: 238 SSYMTGSAITADGGYT 253 >5B1Y-A nrPDB Length = 270 Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 76/238 (31%), Positives = 116/238 (48%), Gaps = 37/238 (15%) Query: 10 VTGAGKGIGYATALAFVEAG--------------------AKVTGFDQAFTQEQYPFATE 49 VTG +GIG AT L F G A+ G +A+T Sbjct: 28 VTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAEEARRLGSPEAYTVR------- 80 Query: 50 VMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 +DV D V ++ R+ L+ LVNAAG+L++G ++ S +W++T VN+ G + Sbjct: 81 -VDVGDPDSVTEMSSRVGELIPHLNVLVNAAGVLQLGGIEETSISEWEETLRVNLTGVYL 139 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPR-IGMSAYGASKAALKSLALSVGLELAGSGVR 168 + + + R+ + +IV VAS A T + AY ASKA + L + ++LAG G+R Sbjct: 140 VTKLLLPLLRKAKWASIVNVASIAGETGNVVAGVAYSASKAGVIGLTKRLAVQLAGYGIR 199 Query: 169 CNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLA 226 N V+P +TDM R+ D E+R E+ PL I +P+++A ILFLA Sbjct: 200 VNAVAPSFVETDMTRSFL---DTPEKR-----ERIASLHPLKIILKPEDVAEAILFLA 249 >3FTP-A nrPDB Length = 270 Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 77/244 (31%), Positives = 113/244 (46%), Gaps = 20/244 (8%) Query: 10 VTGAGKGIGYATALAFVEAGAKVTG----------FDQAFTQEQYPFATEVMDVADAAQV 59 VTGA +GIG A AL GA V G AF Q V++V DA V Sbjct: 33 VTGASRGIGRAIALELARRGAMVIGTATTEAGAEGIGAAFKQAGLEGRGAVLNVNDATAV 92 Query: 60 AQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFR 119 + + L E L+ LVN AGI + ++ ++W N+ F L + + Sbjct: 93 DALVESTLKEFGALNVLVNNAGITQDQLAMRMKDDEWDAVIDTNLKAVFRLSRAVLRPMM 152 Query: 120 RQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDT 179 + RGG IV + S G Y A+KA + + ++ E+ G+ N V+PG DT Sbjct: 153 KARGGRIVNITSVVGSAGNPGQVNYAAAKAGVAGMTRALAREIGSRGITVNCVAPGFIDT 212 Query: 180 DMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIV 239 DM + L +EQ+ K IPLG++ P++IA+ + FLAS A +IT + Sbjct: 213 DMTKGL-----PQEQQ-----TALKTQIPLGRLGSPEDIAHAVAFLASPQAGYITGTTLH 262 Query: 240 VDGG 243 V+GG Sbjct: 263 VNGG 266 >2C07-A nrPDB Length = 285 Score = 106 bits (265), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 70/253 (27%), Positives = 118/253 (46%), Gaps = 22/253 (8%) Query: 3 FSGKN--VWVTGAGKGIGYATALAFVEAGAKVTGFDQ------AFTQEQYPFATEVM--- 51 + G+N VTGAG+GIG A ++ + V + + E F E Sbjct: 40 YCGENKVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKSFGYESSGYA 99 Query: 52 -DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 DV+ ++++V ++L E + +D LVN AGI R ++ ++W+ N+ F + Sbjct: 100 GDVSKKEEISEVINKILTEHKNVDILVNNAGITRDNLFLRMKNDEWEDVLRTNLNSLFYI 159 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 Q + R G I+ ++S T +G + Y +SKA + S+ ELA + N Sbjct: 160 TQPISKRMINNRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKELASRNITVN 219 Query: 171 VVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 230 ++PG +DM +D EQ + IP G++ P+E+AN FL+SD + Sbjct: 220 AIAPGFISSDM------TDKISEQ----IKKNIISNIPAGRMGTPEEVANLACFLSSDKS 269 Query: 231 SHITLQDIVVDGG 243 +I + V+DGG Sbjct: 270 GYINGRVFVIDGG 282 >3F9I-A nrPDB Length = 249 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 76/250 (30%), Positives = 126/250 (50%), Gaps = 21/250 (8%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKV--TGFDQAFTQE-----QYPFATEVMDV 53 +D +GK +TGA GIG A A + G+KV +G ++ + + + EV ++ Sbjct: 10 IDLTGKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYTIEVCNL 69 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 A+ + C L+++T LD LV AGI ++ +D+ + +N+ F L ++ Sbjct: 70 ANKEE----CSNLISKTSNLDILVCNAGITSDTLAIRMKDQDFDKVIDINLKANFILNRE 125 Query: 114 TMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 + + ++R G I+ ++S G + Y ASKA L + S+ E+A G+ N V+ Sbjct: 126 AIKKMIQKRYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYEVATRGITVNAVA 185 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 PG +DM L E+QR E IPLG P+++A + FLAS+ AS+I Sbjct: 186 PGFIKSDMTDKL-----NEKQR-----EAIVQKIPLGTYGIPEDVAYAVAFLASNNASYI 235 Query: 234 TLQDIVVDGG 243 T Q + V+GG Sbjct: 236 TGQTLHVNGG 245 >4IIN-A nrPDB Length = 271 Score = 105 bits (263), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 73/254 (28%), Positives = 116/254 (45%), Gaps = 21/254 (8%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKV-----------TGFDQAFTQEQYPFATE 49 M F+GKNV +TGA KGIG A G KV ++ Y A Sbjct: 25 MQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVI 84 Query: 50 VMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 D A + + Q ++ L LVN AG++R ++ ED+ N+ AF Sbjct: 85 KFDAASESDFIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLTSAFI 144 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 ++ + + R G++V VAS +G + Y ASK + +++ S E A +R Sbjct: 145 GCREALKVMSKSRFGSVVNVASIIGERGNMGQTNYSASKGGMIAMSKSFAYEGALRNIRF 204 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N V+PG +TDM L D+ + ++ IPL ++ +E+A + FL SD Sbjct: 205 NSVTPGFIETDMNANL--KDELKADYVK--------NIPLNRLGSAKEVAEAVAFLLSDH 254 Query: 230 ASHITLQDIVVDGG 243 +S+IT + + V+GG Sbjct: 255 SSYITGETLKVNGG 268 >4JRO-A nrPDB Length = 271 Score = 105 bits (261), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 80/257 (31%), Positives = 119/257 (46%), Gaps = 21/257 (8%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKV----TGFDQAFTQE-----QYPFATEVM 51 M GK VTG +GIG A+ + GA + G +A + ++ E M Sbjct: 25 MTLQGKVAVVTGGSRGIGRDIAINLAKEGANIFFNYNGSPEAAEETAKLVAEHGVEVEAM 84 Query: 52 --DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 +VA A V ++ + R+D LVN AGI R ++ +++W +N+ G F Sbjct: 85 KANVAIAEDVDAFFKQAIERFGRVDILVNNAGITRDNLLMRMKEDEWDDVININLKGTFL 144 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 + +QR G I+ +AS G + Y ASKA + L + ELA G+ Sbjct: 145 CTKAVSRTMMKQRAGKIINMASVVGLIGNAGQANYVASKAGVIGLTKTTARELAPRGINV 204 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N V+PG TDM +D +E+ Q IPLG ++IAN +LFLASD Sbjct: 205 NAVAPGFITTDM------TDKLDEKTKEAMLAQ----IPLGAYGTTEDIANAVLFLASDA 254 Query: 230 ASHITLQDIVVDGGSTL 246 + +IT Q + VDGG + Sbjct: 255 SKYITGQTLSVDGGMVM 271 >4IS3-A nrPDB Length = 268 Score = 105 bits (261), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 84/254 (33%), Positives = 124/254 (48%), Gaps = 32/254 (12%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGF-------DQAFTQ--EQYPFATEVMDVA-- 54 K +TG +GIG+A A F++ GAKV+ F D A Q E YP EV+ A Sbjct: 26 KVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYP-EEEVLGFAPD 84 Query: 55 ----DA--AQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAF 108 DA A V QV Q+ RLD ++N AGI ++S+E+++ +NV G F Sbjct: 85 LTSRDAVMAAVGQVAQKY----GRLDVMINNAGITSNNVFSRVSEEEFKHIMDINVTGVF 140 Query: 109 NLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVR 168 N + + G I+ AS + Y ASKA++ L +G E+ +R Sbjct: 141 NGAWCAYQCMKDAKKGVIINTASVTGIFGSLSGVGYPASKASVIGLTHGLGREIIRKNIR 200 Query: 169 CNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASD 228 V+PG +TDM ++ + + G+ + +P+ ++ P+EIAN LFLASD Sbjct: 201 VVGVAPGVVNTDM------TNGNPPEIMEGYLK----ALPMKRMLEPEEIANVYLFLASD 250 Query: 229 LASHITLQDIVVDG 242 LAS IT + VDG Sbjct: 251 LASGITATTVSVDG 264 >5U9P-A nrPDB Length = 265 Score = 104 bits (260), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 74/253 (29%), Positives = 112/253 (44%), Gaps = 18/253 (7%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQ----------AFTQEQYPFATEVMD 52 G+ +TG+G+GIG A EAGA + D+ F E + V D Sbjct: 18 LDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARRFRDEGFAADHAVFD 77 Query: 53 VADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQ 112 VA+ AQV A +D LVN AGI R D +DW VN+ G FN+ Q Sbjct: 78 VAEHAQVRAAIDEFEARVGAIDILVNNAGIQRRAPLDAFEPDDWHALMRVNLDGVFNVAQ 137 Query: 113 QTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVV 172 + G I+ + S + R ++ Y A+K A++ L + + A G++ N + Sbjct: 138 AVARHMIARGHGKIINICSVQSELARPTIAPYAATKGAVRMLTKGMCADWARYGIQANGL 197 Query: 173 SPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASH 232 +PG +T++ R L DDA F + P G+ + E+ +FLAS + Sbjct: 198 APGYFETELNRAL--VDDA------AFSDWLCKRTPAGRWGQVDELCGAAIFLASAASDF 249 Query: 233 ITLQDIVVDGGST 245 + Q + VDGG T Sbjct: 250 VNGQTLFVDGGLT 262 >3EMK-A nrPDB Length = 246 Score = 104 bits (259), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 76/253 (30%), Positives = 123/253 (48%), Gaps = 19/253 (7%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV--------MDV 53 D +G+ VTGA G+G A A A GA + G ++ A E+ ++ Sbjct: 4 DLTGRKALVTGATGGLGEAIARALHAQGA-IVGLHGTREEKLKELAAELGERIFVFPANL 62 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 +D V + Q+ E +D LVN AGI R G ++S EDW VN+ FNL ++ Sbjct: 63 SDREAVKALGQKAEEEMGGVDILVNNAGITRDGLFVRMSDEDWDAVLTVNLTSVFNLTRE 122 Query: 114 TMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 + R+R G I+ + S T G + Y ASKA L + S+ E+A V N ++ Sbjct: 123 LTHPMMRRRNGRIINITSIVGVTGNPGQANYCASKAGLIGFSKSLAQEIASRNVTVNCIA 182 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 PG ++ M L ++ ++ I G IP+ ++ +IA +++LASD A+++ Sbjct: 183 PGFIESAMTGKL---NEKQKDAIMG-------NIPMKRMGVGADIAAAVVYLASDEAAYV 232 Query: 234 TLQDIVVDGGSTL 246 T Q + V+GG + Sbjct: 233 TGQTLHVNGGMAM 245 >5OJG-A nrPDB Length = 260 Score = 103 bits (258), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 77/253 (30%), Positives = 123/253 (48%), Gaps = 17/253 (6%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVT-------GFDQAFTQEQYPFATEVMDVAD 55 F GK VT A KGIG A A ++ GA V D+A + T+V +A Sbjct: 8 FEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIAG 67 Query: 56 AAQVAQVCQRL----LAETERLDALVNAAGI-LRMGATDQLSKEDWQQTFAVNVGGAFNL 110 ++L L + +++ LVN GI G ++S + W + F VNV F + Sbjct: 68 HIASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVKAGFQM 127 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 + ++ GGAI+ AS +A+ G++AYG +K L L ++ + LA +R N Sbjct: 128 TKLVHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRVN 187 Query: 171 VVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 230 ++PG T M + LW + E+ + E I LG++ P + A T+ +LASD + Sbjct: 188 GIAPGVIKTKMSQVLWDGGEDAEKELTDIQE-----IALGRLGVPDDCAGTVAYLASDDS 242 Query: 231 SHITLQDIVVDGG 243 S+IT + I++ GG Sbjct: 243 SYITGEMIIIAGG 255 >4RZH-A nrPDB Length = 247 Score = 103 bits (258), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 89/250 (35%), Positives = 124/250 (49%), Gaps = 27/250 (10%) Query: 10 VTGAGKGIGYATALAFVEAGAKVT-GFDQAFTQEQYPFATEVM-----------DVADAA 57 VTGA +GIG ATALA G KV + Q+ T A E++ +VA+A Sbjct: 11 VTGASRGIGKATALALAATGMKVVVNYAQSSTAADAVVA-EIIANGGEAIAVQANVANAD 69 Query: 58 QVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQ 117 +V Q+ + L + R+D LVN AGI R ++ EDWQ +N+ G F + Sbjct: 70 EVDQLIKTTLDKFSRIDVLVNNAGITRDTLLLRMKLEDWQAVIDLNLTGVFLCTKAVSKL 129 Query: 118 FRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGST 177 +Q+ G I+ + S A G + Y A+KA + +V ELA GV N V+PG Sbjct: 130 MLKQKSGRIINITSVAGMMGNPGQANYSAAKAGVIGFTKTVAKELASRGVTVNAVAPGFI 189 Query: 178 DTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASD-LASHITLQ 236 TDM L +AE QF IPL + +P+E+A TI FLA+D A++IT Q Sbjct: 190 ATDMTENL----NAEPIL------QF---IPLARYGQPEEVAGTIRFLATDPAAAYITGQ 236 Query: 237 DIVVDGGSTL 246 VDGG + Sbjct: 237 TFNVDGGMVM 246 >2UVD-A nrPDB Length = 246 Score = 102 bits (255), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 80/256 (31%), Positives = 121/256 (47%), Gaps = 23/256 (8%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVM----------- 51 GK VTGA +GIG A A+ + GA V Q+ E+ Sbjct: 2 LKGKVALVTGASRGIGRAIAIDLAKQGANVVVNYAGNEQKANEVVDEIKKLGSDAIAVRA 61 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 DVA+A V + ++ + ++D LVN AG+ + ++ +E+W N+ G F L Sbjct: 62 DVANAEDVTNMVKQTVDVFGQVDILVNNAGVTKDNLLMRMKEEEWDTVINTNLKGVF-LC 120 Query: 112 QQTMNQFR-RQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 + +++F RQR G IV +AS T G + Y A+KA + L + ELA + N Sbjct: 121 TKAVSRFMMRQRHGRIVNIASVVGVTGNPGQANYVAAKAGVIGLTKTSAKELASRNITVN 180 Query: 171 VVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 230 ++PG TDM L ++ I+ E KL IP + Q+IAN + F ASD + Sbjct: 181 AIAPGFIATDMTDVL-------DENIK--AEMLKL-IPAAQFGEAQDIANAVTFFASDQS 230 Query: 231 SHITLQDIVVDGGSTL 246 +IT Q + VDGG + Sbjct: 231 KYITGQTLNVDGGMVM 246 >4DMM-A nrPDB Length = 269 Score = 102 bits (255), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 80/246 (32%), Positives = 111/246 (45%), Gaps = 25/246 (10%) Query: 10 VTGAGKGIGYATALAFVEAGAKVT-----------GFDQAFTQEQYPFATEVMDVADAAQ 58 VTGA +GIG A AL AGAKV A DV+ ++ Sbjct: 33 VTGASRGIGRAIALELAAAGAKVAVNYASSAGAADEVVAAIAAAGGEAFAVKADVSQESE 92 Query: 59 VAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQF 118 V + ++ RLD LVN AGI R ++ ++DWQ +N+GG F + Sbjct: 93 VEALFAAVIERWGRLDVLVNNAGITRDTLLLRMKRDDWQSVLDLNLGGVFLCSRAAAKIM 152 Query: 119 RRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTD 178 +QR G I+ +AS G + Y A+KA + L +V ELA G+ N V+PG Sbjct: 153 LKQRSGRIINIASVVGEMGNPGQANYSAAKAGVIGLTKTVAKELASRGITVNAVAPGFIA 212 Query: 179 TDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASD-LASHITLQD 237 TDM L E+ IPLG+ E+A + FLA+D A++IT Q Sbjct: 213 TDMTSEL-------------AAEKLLEVIPLGRYGEAAEVAGVVRFLAADPAAAYITGQV 259 Query: 238 IVVDGG 243 I +DGG Sbjct: 260 INIDGG 265 >3UF0-A nrPDB Length = 273 Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 83/252 (32%), Positives = 121/252 (48%), Gaps = 22/252 (8%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATE-----------VM 51 +G+ VTGAG GIG A A + AGA V + + T A E V Sbjct: 29 LAGRTAVVTGAGSGIGRAIAHGYARAGAHVLAWGR--TDGVKEVADEIADGGGSAEAVVA 86 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 D+AD A V + L A T R+D LVN AGI+ +++S W++ VN+ A+ L Sbjct: 87 DLADLEGAANVAEEL-AATRRVDVLVNNAGIIARAPAEEVSLGRWREVLTVNLDAAWVLS 145 Query: 112 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 171 + G IVT+AS + ++AY ASK A+ L ++ E AG GV N Sbjct: 146 RSFGTAMLAHGSGRIVTIASMLSFQGGRNVAAYAASKHAVVGLTRALASEWAGRGVGVNA 205 Query: 172 VSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLAS 231 ++PG T L A+++R + IP G+ A P+++ +FLASD AS Sbjct: 206 LAPGYVVTANTAAL----RADDER----AAEITARIPAGRWATPEDMVGPAVFLASDAAS 257 Query: 232 HITLQDIVVDGG 243 ++ Q + VDGG Sbjct: 258 YVHGQVLAVDGG 269 >1NFF-A nrPDB Length = 260 Score = 101 bits (252), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 77/253 (30%), Positives = 117/253 (46%), Gaps = 24/253 (9%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV--------MDVA 54 +GK V+G +G+G + A V GAKV F +E A E+ +DV Sbjct: 5 LTGKVALVSGGARGMGASHVRAMVAEGAKVV-FGDILDEEGKAMAAELADAARYVHLDVT 63 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 AQ + L LVN AGIL +G + + +WQ+ VN+ G F + Sbjct: 64 QPAQWKAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLTGVFLGIRAV 123 Query: 115 MNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSP 174 + + G+I+ ++S + Y A+K A++ L S LEL SG+R N + P Sbjct: 124 VKPMKEAGRGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTALELGPSGIRVNSIHP 183 Query: 175 GSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHIT 234 G T M T WV +D + LG+ A P E++N +++LASD +S+ T Sbjct: 184 GLVKTPM--TDWVPEDIFQT-------------ALGRAAEPVEVSNLVVYLASDESSYST 228 Query: 235 LQDIVVDGGSTLG 247 + VVDGG+ G Sbjct: 229 GAEFVVDGGTVAG 241 >4Z9Y-A nrPDB Length = 253 Score = 101 bits (251), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 70/251 (27%), Positives = 123/251 (49%), Gaps = 17/251 (6%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD--------QAFTQEQYPFATEVMDV 53 D GK +TG G+G A+ +AG + G + + T F + D+ Sbjct: 7 DLQGKVALITGCDTGLGQGMAIGLAQAGCDIVGVNIVEPKDTIEKVTALGRRFLSLTADM 66 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 ++ + A++ ++ +AE +D LVN AGI+R + S+++W +N+ F + Q Sbjct: 67 SNVSGHAELVEKAVAEFGHVDILVNNAGIIRREDAIEFSEKNWDDVMNLNIKSVFFMSQT 126 Query: 114 TMNQFRRQ-RGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVV 172 QF +Q +GG I+ +AS + I + +Y ASK+A+ + + E A G+ N + Sbjct: 127 VARQFIKQGKGGKIINIASMLSFQGGIRVPSYTASKSAVMGVTRLMANEWAKHGINVNAI 186 Query: 173 SPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASH 232 +PG T+ + L A+E+R + ++ IP G+ PQ++ +FLAS + + Sbjct: 187 APGYMATNNTQQL----RADEERSKEILDR----IPAGRWGLPQDLMGPSVFLASSASDY 238 Query: 233 ITLQDIVVDGG 243 I I VDGG Sbjct: 239 INGYTIAVDGG 249 >5OVJ-A nrPDB Length = 256 Score = 100 bits (250), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 77/245 (31%), Positives = 121/245 (49%), Gaps = 11/245 (4%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQV 62 F ++V VTG +GIG A A G KV + F + DV D+A V + Sbjct: 22 FVSRSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDLFGVQC-DVTDSAAVDRA 80 Query: 63 CQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQR 122 + + ++ LV AGI + ++++E +++ N+ GAF Q+ +R+R Sbjct: 81 FKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRASRTMQRKR 140 Query: 123 GGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQ 182 G I+ + S + + Y A+KA L +A S+ ELA +GV NVV+PG DT+M Sbjct: 141 FGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPGYIDTEMT 200 Query: 183 RTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDG 242 R L ++RI+ F IP ++ +E+A + FLAS+ AS+I I VDG Sbjct: 201 RAL-------DERIQAGALDF---IPAKRVGTAEEVAGAVSFLASEDASYIAGAVIPVDG 250 Query: 243 GSTLG 247 G +G Sbjct: 251 GMGMG 255 >5OVL-A nrPDB Length = 300 Score = 100 bits (250), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 77/245 (31%), Positives = 121/245 (49%), Gaps = 11/245 (4%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQV 62 F ++V VTG +GIG A A G KV + F + DV D+A V + Sbjct: 66 FVSRSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDLFGVQC-DVTDSAAVDRA 124 Query: 63 CQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQR 122 + + ++ LV AGI + ++++E +++ N+ GAF Q+ +R+R Sbjct: 125 FKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRASRTMQRKR 184 Query: 123 GGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQ 182 G I+ + S + + Y A+KA L +A S+ ELA +GV NVV+PG DT+M Sbjct: 185 FGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPGYIDTEMT 244 Query: 183 RTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDG 242 R L ++RI+ F IP ++ +E+A + FLAS+ AS+I I VDG Sbjct: 245 RAL-------DERIQAGALDF---IPAKRVGTAEEVAGAVSFLASEDASYIAGAVIPVDG 294 Query: 243 GSTLG 247 G +G Sbjct: 295 GMGMG 299 >1CYD-A nrPDB Length = 244 Score = 100 bits (249), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 80/250 (32%), Positives = 123/250 (49%), Gaps = 19/250 (7%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKV-----TGFDQAFTQEQYPFATEV-MDVA 54 ++FSG VTGAGKGIG T A +GAKV T D ++ P V +D+ Sbjct: 3 LNFSGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPGIEPVCVDLG 62 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 D ++ L +D LVN A ++ M +++KE + ++F+VN+ F + Q Sbjct: 63 DW----DATEKALGGIGPVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNLRSVFQVSQMV 118 Query: 115 -MNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 + R G+IV V+S AH + Y ++K A+ L ++ +EL +R N V+ Sbjct: 119 ARDMINRGVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMELGPHKIRVNSVN 178 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 P TDM + VS D E F + K PL K A +++ N+ILFL SD ++ Sbjct: 179 PTVVLTDMGKK--VSADPE------FARKLKERHPLRKFAEVEDVVNSILFLLSDRSAST 230 Query: 234 TLQDIVVDGG 243 + I+VD G Sbjct: 231 SGGGILVDAG 240 >3O4R-A nrPDB Length = 261 Score = 100 bits (249), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 80/259 (30%), Positives = 122/259 (47%), Gaps = 31/259 (11%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVT-------GFDQAFTQEQYPFATEVMDVAD 55 + K VT + GIG+A A + GA V DQA Q + V Sbjct: 13 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 72 Query: 56 AAQVAQVCQRLLAETERL----DALV-NAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 + A+ +RL+A +L D LV NAA G+ +++E W +T +NV + Sbjct: 73 VGK-AEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALM 131 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 + + + ++ GG++V V+S AA +P G S Y SK AL L ++ +ELA +R N Sbjct: 132 TKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVN 191 Query: 171 VVSPGSTDTDMQRTLWVSDDAEEQ-----RIRGFGEQFKLGIPLGKIARPQEIANTILFL 225 ++PG T R LW+ + EE RIR GE P++ A + FL Sbjct: 192 CLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGE-------------PEDCAGIVSFL 238 Query: 226 ASDLASHITLQDIVVDGGS 244 S+ AS+IT + +VV GG+ Sbjct: 239 CSEDASYITGETVVVGGGT 257 >2CFC-A nrPDB Length = 250 Score = 99.8 bits (247), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 83/250 (33%), Positives = 117/250 (46%), Gaps = 22/250 (8%) Query: 10 VTGAGKGIGYATALAFVEAGAKVTGFD-QAFTQEQ------YPFATEVM----DVADAAQ 58 VTGA G G A A F+ G +V D A T E+ + +A +V+ DVAD Sbjct: 7 VTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYADKVLRVRADVADEGD 66 Query: 59 VAQVCQRLLAETERLDALVNAAGIL---RMGATDQLSKEDWQQTFAVNVGGAFNLFQQTM 115 V + + +D LVN AGI G E + + AVNV G F + + Sbjct: 67 VNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVRGIFLGCRAVL 126 Query: 116 NQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPG 175 Q G IV +AS A+ G SAY SK A+ L SV ++ AGSG+RCN V PG Sbjct: 127 PHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDYAGSGIRCNAVCPG 186 Query: 176 STDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITL 235 +T M T W D E +Q IP +I ++A+ ++FLA + A+++ Sbjct: 187 MIETPM--TQWRLDQPE------LRDQVLARIPQKEIGTAAQVADAVMFLAGEDATYVNG 238 Query: 236 QDIVVDGGST 245 +V+DG T Sbjct: 239 AALVMDGAYT 248 >1UZM-A nrPDB Length = 247 Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 76/245 (31%), Positives = 122/245 (49%), Gaps = 11/245 (4%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQV 62 F ++V VTG +GIG A A G KV + + F EV DV D+ V + Sbjct: 13 FVSRSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPKGLFGVEV-DVTDSDAVDRA 71 Query: 63 CQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQR 122 + ++ LV+ AG+ ++++E +++ N+ GAF + Q+ +R + Sbjct: 72 FTAVEEHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNK 131 Query: 123 GGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQ 182 G ++ + S + + Y ASKA + +A S+ EL+ + V NVV+PG DTDM Sbjct: 132 FGRMIFIGSVSGLWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAPGYIDTDMT 191 Query: 183 RTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDG 242 R L ++RI+ QF IP ++ P E+A + FLAS+ AS+I+ I VDG Sbjct: 192 RAL-------DERIQQGALQF---IPAKRVGTPAEVAGVVSFLASEDASYISGAVIPVDG 241 Query: 243 GSTLG 247 G +G Sbjct: 242 GMGMG 246 >3GRP-A nrPDB Length = 266 Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 73/254 (28%), Positives = 121/254 (47%), Gaps = 23/254 (9%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGA----------KVTGFDQAFTQEQYPFATEVMD 52 +G+ VTGA GIG A A F GA K+ ++ + F+ + D Sbjct: 25 LTGRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADLGKDVFVFSANLSD 84 Query: 53 VADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQ 112 Q+A+V +R E E +D LVN AGI R G ++ +DW AVN+ A L + Sbjct: 85 RKSIKQLAEVAER---EMEGIDILVNNAGITRDGLFVRMQDQDWDDVLAVNLTAASTLTR 141 Query: 113 QTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVV 172 + ++ R+R G I+ + S G + Y A+KA L + ++ E+A + N + Sbjct: 142 ELIHSMMRRRYGRIINITSIVGVVGNPGQTNYCAAKAGLIGFSKALAQEIASRNITVNCI 201 Query: 173 SPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASH 232 +PG + M L E+Q+ E IP+ ++ +EIA ++LASD A++ Sbjct: 202 APGFIKSAMTDKL-----NEKQK-----EAIMAMIPMKRMGIGEEIAFATVYLASDEAAY 251 Query: 233 ITLQDIVVDGGSTL 246 +T Q + ++GG + Sbjct: 252 LTGQTLHINGGMAM 265 >4K6F-A nrPDB Length = 255 Score = 98.6 bits (244), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 70/248 (28%), Positives = 115/248 (46%), Gaps = 20/248 (8%) Query: 10 VTGAGKGIGYATALAFVEAGAKV--------TGFDQAFTQEQ---YPFATEVMDVADAAQ 58 VTG G+G A ++ +AG +V TG D+ T+ F +DVAD Sbjct: 16 VTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNTGADRWLTEMHAAGREFHAYPVDVADHDS 75 Query: 59 VAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQF 118 Q ++++ + +D LVN AGI R +L K +W N+ FN+ + + Sbjct: 76 CQQCIEKIVRDVGPVDILVNNAGITRDMTLRKLDKVNWDAVIRTNLDSVFNMTKPVCDGM 135 Query: 119 RRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTD 178 + G IV ++S +G + Y A+KA + S+ LE+A GV N VSPG Sbjct: 136 VERGWGRIVNISSVNGSKGSVGQTNYAAAKAGMHGFTKSLALEIARKGVTVNTVSPGYLA 195 Query: 179 TDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDI 238 T M + D + +I IP G++ +P+E+A + +L S+ A +T +I Sbjct: 196 TKMVTA--IPQDILDTKILP-------QIPAGRLGKPEEVAALVAYLCSEEAGFVTGSNI 246 Query: 239 VVDGGSTL 246 ++GG + Sbjct: 247 AINGGQHM 254 >6NRP-A nrPDB Length = 263 Score = 97.8 bits (242), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 72/250 (28%), Positives = 123/250 (49%), Gaps = 25/250 (10%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV-----------MDVA 54 + + VTG+ +GIG A AL +AG VT ++ E E+ DV Sbjct: 25 RRILVTGSSRGIGKAIALQLAKAGFDVTVHARSRQAEAEQVVQEIQALGQNSHYLMFDVN 84 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ- 113 + V Q+ ++ + + +V AG+ GA L+ +DW + + ++ G +N+ + Sbjct: 85 ERQTVQQILEQDVEQHGGFYGVVLNAGLTHDGAFPALTDQDWDEVISTSLDGFYNVLKPL 144 Query: 114 TMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 M ++GG IVT++S + G Y A+KA L ++ LELA + N V+ Sbjct: 145 IMPMIHLRKGGRIVTLSSVSGIMGNRGQVNYSAAKAGLIGATKALALELAKRKITVNCVA 204 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 PG +T+M V+D+ +E ++ IPL ++ + E+A+ + FL SD AS++ Sbjct: 205 PGLIETEM-----VTDEVKEHALK--------MIPLQRMGQVDEVASVVKFLCSDEASYV 251 Query: 234 TLQDIVVDGG 243 T Q I V+GG Sbjct: 252 TRQVISVNGG 261 >4E6P-A nrPDB Length = 259 Score = 97.4 bits (241), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 79/255 (30%), Positives = 120/255 (47%), Gaps = 17/255 (6%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQ------EQYPFATEV-MDVAD 55 GK+ +TG+ +GIG A A A+V GA V D + E P A V MDV Sbjct: 6 LEGKSALITGSARGIGRAFAEAYVREGATVAIADIDIERARQAAAEIGPAAYAVQMDVTR 65 Query: 56 AAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTM 115 + + LD LVN A + + ++++E +++ FA+NV G Q Sbjct: 66 QDSIDAAIAATVEHAGGLDILVNNAALFDLAPIVEITRESYEKLFAINVAGTLFTLQAAA 125 Query: 116 NQFRRQ-RGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSP 174 Q Q RGG I+ +AS A ++ Y A+KAA+ SL S GL+L + N ++P Sbjct: 126 RQMIAQGRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAGLDLIKHRINVNAIAP 185 Query: 175 GSTDTDMQRTLWVSDDAEEQRI--RGFGEQFKL---GIPLGKIARPQEIANTILFLASDL 229 G D + W DA R R GE+ +L +P G++ +++ +FLAS Sbjct: 186 GVVDGEH----WDGVDALFARYENRPRGEKKRLVGEAVPFGRMGTAEDLTGMAIFLASAE 241 Query: 230 ASHITLQDIVVDGGS 244 + +I Q VDGG+ Sbjct: 242 SDYIVSQTYNVDGGN 256 >3WTC-A nrPDB Length = 262 Score = 97.4 bits (241), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 81/259 (31%), Positives = 121/259 (46%), Gaps = 20/259 (7%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD-QAFTQEQYPFATEVMDVADAAQV 59 M SGK VTGA +GIG A AL + GA V D + T + E + A Sbjct: 4 MSLSGKIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEALGRRAVALT 63 Query: 60 AQVCQR-----LLAETER----LDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 A + R LA+ + LD +VN AGI ++ + + ++ F++NV G Sbjct: 64 ADISNRDQFRSTLADAAKTLGGLDIMVNNAGICQVKPILDIEPAEIEKIFSINVQGVLWG 123 Query: 111 FQQTMNQFRRQ-RGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 Q F+ + G I+ S A H + AY A+K A+++L S ELA SG+ Sbjct: 124 MQAAATLFKEKGTKGKIINACSIAGHEGYPLLGAYSATKFAVRALTQSAAKELASSGITV 183 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRG--FGEQFKL---GIPLGKIARPQEIANTILF 224 N PG TDM WV+ D I G G +K GI LG++ ++A + + Sbjct: 184 NSYCPGIVGTDM----WVTIDKRMAEITGTEIGATYKKYVEGIALGRVETADDVAGFVAY 239 Query: 225 LASDLASHITLQDIVVDGG 243 L+S A ++T Q +++DGG Sbjct: 240 LSSSDADYMTGQSVLIDGG 258 >4BO1-A nrPDB Length = 269 Score = 97.1 bits (240), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 74/253 (29%), Positives = 112/253 (44%), Gaps = 20/253 (7%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTG----------FDQAFTQEQYPFATEV 50 M GK VTGA +GIG A AL GA V G + A V Sbjct: 23 MSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLV 82 Query: 51 MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 +DV+ VA + + + +VN AGI R ++ ++W N+ + L Sbjct: 83 LDVSSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEWFDVVNTNLNSLYRL 142 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 + + + R G I+ + S G + Y A+KA L+ ++ E+ + N Sbjct: 143 SKAVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAITVN 202 Query: 171 VVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 230 V+PG DTDM R L E QR G+ IPLG++ + +EIA + FLASD A Sbjct: 203 AVAPGFIDTDMTREL-----PEAQREALLGQ-----IPLGRLGQAEEIAKVVGFLASDGA 252 Query: 231 SHITLQDIVVDGG 243 +++T + V+GG Sbjct: 253 AYVTGATVPVNGG 265 >1GEE-A nrPDB Length = 261 Score = 97.1 bits (240), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 72/257 (28%), Positives = 117/257 (45%), Gaps = 20/257 (7%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVM---------- 51 D GK V +TG+ G+G + A+ F AKV ++ E E+ Sbjct: 4 DLEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKVGGEAIAVK 63 Query: 52 -DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 DV + V + Q + E +LD ++N AG+ ++ ++S DW + N+ GAF Sbjct: 64 GDVTVESDVINLVQSAIKEFGKLDVMINNAGLENPVSSHEMSLSDWNKVIDTNLTGAFLG 123 Query: 111 FQQTMNQF-RRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 ++ + F G ++ ++S P Y ASK +K + ++ LE A G+R Sbjct: 124 SREAIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRV 183 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N + PG+ +T + + EQR + IP+G I P+EIA +LAS Sbjct: 184 NNIGPGAINTPINAEKFADP---EQR-----ADVESMIPMGYIGEPEEIAAVAAWLASSE 235 Query: 230 ASHITLQDIVVDGGSTL 246 AS++T + DGG TL Sbjct: 236 ASYVTGITLFADGGMTL 252 >5VT6-A nrPDB Length = 269 Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 61/198 (30%), Positives = 96/198 (48%), Gaps = 9/198 (4%) Query: 46 FATEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVG 105 F +DVAD + +++LA+ ++D L+N AGI R +++K DW ++ Sbjct: 77 FKAYAVDVADFESCERCAEKVLADFGKVDVLINNAGITRDATFMKMTKGDWDAVMRTDLD 136 Query: 106 GAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGS 165 FN+ +Q + +R G IV + S G + Y ++KA + ++ LE A Sbjct: 137 AMFNVTKQFIAGMVERRFGRIVNIGSVNGSRGAFGQANYASAKAGIHGFTKTLALETAKR 196 Query: 166 GVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFL 225 G+ N VSPG T M V D E +I IP+G++ RP E+A I FL Sbjct: 197 GITVNTVSPGYLATAMVEA--VPQDVLEAKIL-------PQIPVGRLGRPDEVAALIAFL 247 Query: 226 ASDLASHITLQDIVVDGG 243 SD A +T D+ ++GG Sbjct: 248 CSDDAGFVTGADLAINGG 265 >3V2G-A nrPDB Length = 271 Score = 95.5 bits (236), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 78/257 (30%), Positives = 109/257 (42%), Gaps = 25/257 (9%) Query: 1 MDFSGKNVWVTGAGKGIGYA-----------TALAFVEAGAKVTGFDQAFTQEQYPFATE 49 + +GK +VTG +GIG A AL +V A + Q Sbjct: 27 ISLAGKTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQAGGRAVAI 86 Query: 50 VMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 D DA + Q + + LD LVN+AGI ++ + D+ + AVN F Sbjct: 87 RADNRDAEAIEQAIRETVEALGGLDILVNSAGIWHSAPLEETTVADFDEVMAVNFRAPFV 146 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAH-TPRIGMSAYGASKAALKSLALSVGLELAGSGVR 168 + GG I+T+ S+ A P G+S Y ASKAAL L + +L G+ Sbjct: 147 AIRSASRHL--GDGGRIITIGSNLAELVPWPGISLYSASKAALAGLTKGLARDLGPRGIT 204 Query: 169 CNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASD 228 N+V PGSTDTDM D AE QR R I G PQ+IA + +LA Sbjct: 205 VNIVHPGSTDTDMNPA--DGDHAEAQRER---------IATGSYGEPQDIAGLVAWLAGP 253 Query: 229 LASHITLQDIVVDGGST 245 +T + +DGG+ Sbjct: 254 QGKFVTGASLTIDGGAN 270 >1AE1-A nrPDB Length = 273 Score = 93.2 bits (230), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 71/257 (27%), Positives = 114/257 (44%), Gaps = 21/257 (8%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQV 62 G VTG KGIGYA GA+V + + +++ E+ V Sbjct: 19 LKGTTALVTGGSKGIGYAIVEELAGLGARV--YTCSRNEKELDECLEIWREKGLNVEGSV 76 Query: 63 CQRLLAETER--------------LDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAF 108 C LL+ TER L+ LVN AG++ +++D+ N A+ Sbjct: 77 CD-LLSRTERDKLMQTVAHVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFEAAY 135 Query: 109 NLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVR 168 +L Q + + G ++ ++S A + +S Y ASK A+ + S+ E A +R Sbjct: 136 HLSQIAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLACEWAKDNIR 195 Query: 169 CNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASD 228 N V+PG T + T + +++ I + F + P+G+ +PQE++ I FL Sbjct: 196 VNSVAPGVILTPLVETAIKKNPHQKEEI----DNFIVKTPMGRAGKPQEVSALIAFLCFP 251 Query: 229 LASHITLQDIVVDGGST 245 AS+IT Q I DGG T Sbjct: 252 AASYITGQIIWADGGFT 268 >2CDH-G nrPDB Length = 244 Score = 92.8 bits (229), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 77/248 (31%), Positives = 113/248 (45%), Gaps = 22/248 (8%) Query: 8 VWVTGAGKGIGYATALAFVEAGAKV--TGFDQAFTQEQYPFATEVM---------DVADA 56 V VTGA +GIG A AL+ +AG KV A E+ E DV+ Sbjct: 4 VVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKAAEEVSKQIEAYGGQAITFGGDVSKE 63 Query: 57 AQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMN 116 A V + + + +D +VN AGI R ++ K W + +N+ G F Q Sbjct: 64 ADVEAMMKTAIDAWGTIDVVVNNAGITRDTLLIRMKKSQWDEVIDLNLTGVFLCTQAATK 123 Query: 117 QFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGS 176 ++R G I+ +AS IG + Y A+KA + + + E A + NVV PG Sbjct: 124 IMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNINVNVVCPGF 183 Query: 177 TDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLA-SDLASHITL 235 +DM L + E++I G IPLG+ +P+ +A + FLA S AS+IT Sbjct: 184 IASDMTAKL---GEDMEKKILGT-------IPLGRTGQPENVAGLVEFLALSPAASYITG 233 Query: 236 QDIVVDGG 243 Q +DGG Sbjct: 234 QAFTIDGG 241 >3WYE-A nrPDB Length = 256 Score = 92.0 bits (227), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 85/255 (33%), Positives = 128/255 (50%), Gaps = 22/255 (8%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFD------QAFTQE-----QYPFATEVMDVA 54 K VTGAG+GIG A AL V+ G V D +A E + A +V DV+ Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKV-DVS 61 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 D QV ++ D +VN AGI ++ ++++ED +Q ++VNV F Q Sbjct: 62 DRDQVFAAVEQARKTLGGFDVIVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQAA 121 Query: 115 MNQFRRQ-RGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 + F+++ GG I+ AS AA +SAY +K A++ L + +LA G+ N Sbjct: 122 VEAFKKEGHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAARDLAPLGITVNGYC 181 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRG--FGEQFK---LGIPLGKIARPQEIANTILFLASD 228 PG T M W DAE +I G GE FK I LG+ + P+++A + FLAS Sbjct: 182 PGIVGTGM----WEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLASP 237 Query: 229 LASHITLQDIVVDGG 243 + ++T Q +++DGG Sbjct: 238 DSDYMTGQSLLIDGG 252 >2PH3-A nrPDB Length = 245 Score = 91.7 bits (226), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 58/173 (33%), Positives = 83/173 (47%), Gaps = 10/173 (5%) Query: 73 LDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASD 132 LD LVN AGI R ++ EDW+ N+ F ++ + + R G IV + S Sbjct: 81 LDTLVNNAGITRDTLLVRMKDEDWEAVLEANLSAVFRTTREAVKLMMKARFGRIVNITSV 140 Query: 133 AAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAE 192 G + Y ASKA L +V E A G+ N V+PG +T+M L Sbjct: 141 VGILGNPGQANYVASKAGLIGFTRAVAKEYAQRGITVNAVAPGFIETEMTERL------- 193 Query: 193 EQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDGGST 245 Q ++ E + IP G+ RP+E+A + FL S+ A +IT Q + VDGG T Sbjct: 194 PQEVK---EAYLKQIPAGRFGRPEEVAEAVAFLVSEKAGYITGQTLCVDGGLT 243 >3AUT-A nrPDB Length = 269 Score = 91.3 bits (225), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 70/256 (27%), Positives = 113/256 (44%), Gaps = 20/256 (7%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVM---------- 51 D K V +TG G+G A A+ F + AKV +E EV Sbjct: 12 DLKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQAIIVQ 71 Query: 52 -DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 DV V + Q + E LD ++N AG+ + +LS ++W + N+ GAF Sbjct: 72 GDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGAFLG 131 Query: 111 FQQTMNQF-RRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 ++ + F G ++ ++S P Y ASK +K + ++ LE A G+R Sbjct: 132 SREAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRV 191 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N + PG+ +T + + +D + + IP+G I +P+E+A FLAS Sbjct: 192 NNIGPGAMNTPINAEKF-ADPVQRADVESM-------IPMGYIGKPEEVAAVAAFLASSQ 243 Query: 230 ASHITLQDIVVDGGST 245 AS++T + DGG T Sbjct: 244 ASYVTGITLFADGGMT 259 >4AVY-A nrPDB Length = 242 Score = 91.3 bits (225), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 77/245 (31%), Positives = 108/245 (44%), Gaps = 19/245 (7%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGF----DQAFTQEQYPFATEVMDVADAAQ 58 ++G+ V VTG GIG A A+ F E GA+V D E +D+ D+ Sbjct: 9 YAGQQVLVTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHAPRHPRIRREELDITDS-- 66 Query: 59 VAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQF 118 Q QRL RLD LVN AGI R ++ +++ +N+ A L Q Sbjct: 67 --QRLQRLFEALPRLDVLVNNAGISR--DREEYDLATFERVLRLNLSAAM-LASQLARPL 121 Query: 119 RRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTD 178 QRGG+I+ +AS + AY ASK A+ L S+ E A +R N ++PG D Sbjct: 122 LAQRGGSILNIASMYSTFGSADRPAYSASKGAIVQLTRSLACEYAAERIRVNAIAPGWID 181 Query: 179 TDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDI 238 T + L D E R + PL + E+A+ FL AS +T + Sbjct: 182 TPLGAGL--KADVEATR------RIMQRTPLARWGEAPEVASAAAFLCGPGASFVTGAVL 233 Query: 239 VVDGG 243 VDGG Sbjct: 234 AVDGG 238 >5T5Q-A nrPDB Length = 247 Score = 91.3 bits (225), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 77/253 (30%), Positives = 118/253 (46%), Gaps = 26/253 (10%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVT-------GFDQAFTQEQYP--FATEVMD 52 +F + + +TGA GIG A A F +GA + G D P AT D Sbjct: 6 EFENRTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSPERIATIKAD 65 Query: 53 VADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQ 112 + A + + +D LV +AGI + ++S DW +T ++N+ G F L + Sbjct: 66 ASSADDAEKTVALAMERFGGIDFLVPSAGIYQAKPFAEMSDADWHRTISINLDGVFYLCK 125 Query: 113 QTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVV 172 + + + +IVT+AS AA+ + YGA+K A+ S+ ++ ELA R N V Sbjct: 126 RALPALKED--SSIVTLASLAAYRGAYVNAHYGATKGAMVSMTRALSRELAPK-TRVNGV 182 Query: 173 SPGSTDTDMQRTLWVS--DDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 230 SPG +T M L + D+ Q PL ++ +P EIA+ I FL S A Sbjct: 183 SPGIIETPMTSELLKTRMDETMTQ------------TPLKRLGKPSEIASVIAFLCSPAA 230 Query: 231 SHITLQDIVVDGG 243 S +T + I V+GG Sbjct: 231 SFVTGETIQVNGG 243 >3UN1-A nrPDB Length = 260 Score = 91.3 bits (225), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 66/245 (26%), Positives = 114/245 (46%), Gaps = 18/245 (7%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYP-FATEVMDVADAAQVAQVCQ 64 K V +TGA +GIG A+ + +V ++ P T D++ ++ + Sbjct: 29 KVVVITGASQGIGAGLVRAYRDRNYRVVATSRSIKPSADPDIHTVAGDISKPETADRIVR 88 Query: 65 RLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGG 124 + R+D+LVN AG+ ++++ED+ VNV G F++ Q+ + +Q G Sbjct: 89 EGIERFGRIDSLVNNAGVFLAKPFVEMTQEDYDHNLGVNVAGFFHITQRAAAEMLKQGSG 148 Query: 125 AIVTVASDAAHTPRIGMSAYGAS--KAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQ 182 IV++ + P +GM + AS K L ++ S+ +E + SGVR N VSPG T M Sbjct: 149 HIVSITTSLVDQPMVGMPSALASLTKGGLNAVTRSLAMEFSRSGVRVNAVSPGVIKTPMH 208 Query: 183 RTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDG 242 S A P+G++ +++ + +L+L + A IT + + VDG Sbjct: 209 PAETHSTLAGLH-------------PVGRMGEIRDVVDAVLYL--EHAGFITGEILHVDG 253 Query: 243 GSTLG 247 G G Sbjct: 254 GQNAG 258 >3EZL-A nrPDB Length = 256 Score = 90.9 bits (224), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 57/204 (27%), Positives = 97/204 (47%), Gaps = 10/204 (4%) Query: 44 YPFATEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVN 103 + F +V D Q ++ AE +D LVN AGI R ++++EDWQ N Sbjct: 63 FDFYASEGNVGDWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTREDWQAVIDTN 122 Query: 104 VGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELA 163 + FN+ +Q ++ + G I+ ++S + G + Y +KA + +S+ E+A Sbjct: 123 LTSLFNVTKQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVA 182 Query: 164 GSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTIL 223 GV N VSPG TDM + + D E+ + IP+ ++ P EI + + Sbjct: 183 TKGVTVNTVSPGYIGTDMVKA--IRPDVLEKIV--------ATIPVRRLGSPDEIGSIVA 232 Query: 224 FLASDLASHITLQDIVVDGGSTLG 247 +LAS+ + T D ++GG +G Sbjct: 233 WLASEESGFSTGADFSLNGGLHMG 256 >3D3W-A nrPDB Length = 244 Score = 90.5 bits (223), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 74/248 (29%), Positives = 111/248 (44%), Gaps = 19/248 (7%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQ------AFTQEQYPFATEVMDVADA 56 +G+ V VTGAGKGIG T A GA+V + + +E +D+ D Sbjct: 5 LAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDW 64 Query: 57 AQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMN 116 + +R L +D LVN A + + +++KE + ++F VN+ + Q Sbjct: 65 ----EATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVAR 120 Query: 117 -QFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPG 175 R GAIV V+S + S Y ++K AL L + LEL +R N V+P Sbjct: 121 GLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPT 180 Query: 176 STDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITL 235 T M + W SD + + + IPLGK A + + N ILFL SD + T Sbjct: 181 VVMTSMGQATW-SDPHKAKTMLNR-------IPLGKFAEVEHVVNAILFLLSDRSGMTTG 232 Query: 236 QDIVVDGG 243 + V+GG Sbjct: 233 STLPVEGG 240 >2HSD-A nrPDB Length = 253 Score = 89.0 bits (219), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 82/254 (32%), Positives = 121/254 (47%), Gaps = 19/254 (7%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQ--- 58 D SGK V +TG +G+G A V AGA+V D +E A E+ D A Sbjct: 2 DLSGKTVIITGGARGLGAEAARQAVAAGARVVLAD-VLDEEGAATARELGDAARYQHLDV 60 Query: 59 -VAQVCQRLLA----ETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 + + QR++A E +D LVN AGI + S E +++ +N+ G F + Sbjct: 61 TIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVEINLTGVFIGMKT 120 Query: 114 TMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 + + GG+IV ++S A S+YGASK ++ L+ +EL +R N V Sbjct: 121 VIPAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVH 180 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 PG T T M E IR GE P+G++ P EIA ++ L SD +S++ Sbjct: 181 PGMTYTPM---------TAETGIR-QGEGNYPNTPMGRVGEPGEIAGAVVKLLSDTSSYV 230 Query: 234 TLQDIVVDGGSTLG 247 T ++ VDGG T G Sbjct: 231 TGAELAVDGGWTTG 244 >1GEG-A nrPDB Length = 256 Score = 88.6 bits (218), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 73/255 (28%), Positives = 120/255 (47%), Gaps = 22/255 (8%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFD------QAFTQE-----QYPFATEVMDVA 54 K VTGAG+GIG A AL V+ G V D +A E + A +V DV+ Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKV-DVS 61 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 D QV ++ D +VN AG+ + ++ E + + +NV G Q Sbjct: 62 DRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWGIQAA 121 Query: 115 MNQFRRQ-RGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 + F+++ GG I+ S A H ++ Y +SK A++ L + +LA G+ N Sbjct: 122 VEAFKKEGHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGITVNGYC 181 Query: 174 PGSTDTDMQRTLWVSDDAEEQ----RIRGFGE-QFKLGIPLGKIARPQEIANTILFLASD 228 PG T M W D + + G+G +F I LG+++ P+++A + +LAS Sbjct: 182 PGIVKTPM----WAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAACVSYLASP 237 Query: 229 LASHITLQDIVVDGG 243 + ++T Q +++DGG Sbjct: 238 DSDYMTGQSLLIDGG 252 >1O5I-A nrPDB Length = 249 Score = 88.6 bits (218), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 68/238 (28%), Positives = 119/238 (50%), Gaps = 14/238 (5%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQR 65 K V V A +GIG A A + GA+VT A +E + V D + + Sbjct: 20 KGVLVLAASRGIGRAVADVLSQEGAEVTIC--ARNEELLKRSGHRYVVCDLRKDLDL--- 74 Query: 66 LLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGA 125 L + + +D LV AG + G D+L+ ED+++ + + + + + G Sbjct: 75 LFEKVKEVDILVLNAGGPKAGFFDELTNEDFKEAIDSLFLNMIKIVRNYLPAMKEKGWGR 134 Query: 126 IVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQRTL 185 IV + S + +P + +++ AL ++ E+A G+ N V+PG T+T+ + L Sbjct: 135 IVAITSFSVISPIENLYTSNSARMALTGFLKTLSFEVAPYGITVNCVAPGWTETERVKEL 194 Query: 186 WVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDGG 243 +EE++ +Q + IP+ ++A+P+EIA+ + FL S+ AS++T Q IVVDGG Sbjct: 195 L----SEEKK-----KQVESQIPMRRMAKPEEIASVVAFLCSEKASYLTGQTIVVDGG 243 >3V8B-A nrPDB Length = 283 Score = 88.2 bits (217), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 82/253 (32%), Positives = 126/253 (49%), Gaps = 20/253 (7%) Query: 10 VTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVM-----------DVADAAQ 58 +TGAG GIG ATALA G V + T+ + A E++ DV+D Q Sbjct: 33 ITGAGSGIGRATALALAADGVTVGALGRTRTEVEE-VADEIVGAGGQAIALEADVSDELQ 91 Query: 59 VAQVCQRLLAETERLDALVNAAGILRMGAT-DQLSKEDWQQTFAVNVGGAFNLFQQTMNQ 117 + + L+ + LD +V AGI + A D L +W +T AVN+ G F T+ Sbjct: 92 MRNAVRDLVLKFGHLDIVVANAGINGVWAPIDDLKPFEWDETIAVNLRGTFLTLHLTVPY 151 Query: 118 FRRQRGGAIVTVAS----DAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 +++ GGAIV V+S TP G +AY A+KAA ++ + LEL +R N V Sbjct: 152 LKQRGGGAIVVVSSINGTRTFTTP--GATAYTATKAAQVAIVQQLALELGKHHIRVNAVC 209 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 PG+ +T++ + + EE I + ++ I G+ R +++A I FL S+ A H+ Sbjct: 210 PGAIETNISDNTKLRHE-EETAIPVEWPKGQVPITDGQPGRSEDVAELIRFLVSERARHV 268 Query: 234 TLQDIVVDGGSTL 246 T + +DGG L Sbjct: 269 TGSPVWIDGGQGL 281 >4CQM-B nrPDB Length = 244 Score = 88.2 bits (217), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 65/195 (33%), Positives = 91/195 (46%), Gaps = 15/195 (7%) Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 DVA V + L R++ LVNAAGI R G + ED N+ G+ Sbjct: 63 DVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTC 122 Query: 112 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 171 + M +Q+GG+IV V S G S Y ASK L + ++ E+A +R NV Sbjct: 123 KAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNV 182 Query: 172 VSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLAS 231 V+PG TDM + D +E E K IPLG+ E+A+ ++FL + Sbjct: 183 VAPGFVHTDMTK------DLKE-------EHLKKNIPLGRFGETIEVAHAVVFLLE--SP 227 Query: 232 HITLQDIVVDGGSTL 246 +IT +VVDGG L Sbjct: 228 YITGHVLVVDGGLQL 242 >3OEC-A nrPDB Length = 317 Score = 88.2 bits (217), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 73/272 (26%), Positives = 117/272 (43%), Gaps = 34/272 (12%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFA--------------- 47 GK ++TGA +G G A+ + GA + D Q +A Sbjct: 44 LQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKETVRLVE 103 Query: 48 -------TEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTF 100 DV D A + V LAE +D LV+ GI G L+ + W Sbjct: 104 EQGRRIIARQADVRDLASLQAVVDEALAEFGHIDILVSNVGISNQGEVVSLTDQQWSDIL 163 Query: 101 AVNVGGAFNLFQQTM-NQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVG 159 N+ GA++ + + + R +GG+++ V+S G S Y ASK ++ L LS+ Sbjct: 164 QTNLIGAWHACRAVLPSMIERGQGGSVIFVSSTVGLRGAPGQSHYAASKHGVQGLMLSLA 223 Query: 160 LELAGSGVRCNVVSPGSTDTDM---QRTL-----WVSDDAEEQRIRGFGEQFKLGIPLGK 211 E+ +R N V+PG+ +T+M ++ L + + E F + L IP Sbjct: 224 NEVGRHNIRVNSVNPGAVNTEMALNEKLLKMFLPHLENPTREDAAELFSQLTLLPIPW-- 281 Query: 212 IARPQEIANTILFLASDLASHITLQDIVVDGG 243 P++++N + +LASD A +I I VDGG Sbjct: 282 -VEPEDVSNAVAWLASDEARYIHGAAIPVDGG 312 >2B4Q-A nrPDB Length = 276 Score = 87.0 bits (214), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 76/265 (28%), Positives = 117/265 (44%), Gaps = 34/265 (12%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKV--------TGFDQAFTQEQYPFATEV-MD 52 +G+ VTG +GIG A +EAGA+V D A Y + D Sbjct: 26 SLAGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYGDCQAIPAD 85 Query: 53 VADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQ 112 ++ A ++ Q L + RLD LVN AG A + W++ +NV F+ Q Sbjct: 86 LSSEAGARRLAQALGELSARLDILVNNAGTSWGAALESYPVSGWEKVMQLNVTSVFSCIQ 145 Query: 113 QTMNQFRR----QRGGAIVTVASDAAHTPRIGMSA-------YGASKAALKSLALSVGLE 161 Q + RR + ++ + S A G+SA YG SKAAL L+ + E Sbjct: 146 QLLPLLRRSASAENPARVINIGSVA------GISAMGEQAYAYGPSKAALHQLSRMLAKE 199 Query: 162 LAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANT 221 L G + NV++PG + M R +++D + E IP+G+ RP+E+A Sbjct: 200 LVGEHINVNVIAPGRFPSRMTRH--IANDPQAL------EADSASIPMGRWGRPEEMAAL 251 Query: 222 ILFLASDLASHITLQDIVVDGGSTL 246 + LA +++T I +DGG L Sbjct: 252 AISLAGTAGAYMTGNVIPIDGGFHL 276 >4NBV-A nrPDB Length = 246 Score = 86.7 bits (213), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 76/256 (29%), Positives = 114/256 (44%), Gaps = 20/256 (7%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD--QAFTQEQY--------PFATEV 50 M G+ +TGA GIG+ATA F E GA V D +A +E + Sbjct: 1 MKLQGRVAIITGAAAGIGFATAQRFAEDGAIVVLCDVQEARVREAAARLAATGATVSAYR 60 Query: 51 MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 +DV +V + +LA +R+D LVN AGI + ++++ + VN+ G FN Sbjct: 61 VDVTRRDEVDAMVAAVLAAHQRVDILVNNAGITKDARLAKMTEAQFDAVIDVNLKGVFNC 120 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 Q Q G I+ +S G + Y ASK + + EL GVR N Sbjct: 121 AQAVAGLMTEQGKGVILNASSVVGLYGNFGQTNYAASKFGVIGFTKTWARELGPKGVRVN 180 Query: 171 VVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 230 V PG +T++ +T+ ++ + G L ++A P EIA+ FLASD A Sbjct: 181 AVCPGFVNTEILQTV------PDKVLDGMTSS----CWLRRLAEPAEIASIYAFLASDDA 230 Query: 231 SHITLQDIVVDGGSTL 246 S++ I GG +L Sbjct: 231 SYVNGVAIEASGGMSL 246 >4MOW-A nrPDB Length = 256 Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 70/252 (27%), Positives = 113/252 (44%), Gaps = 20/252 (7%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVT--------GFD---QAFTQEQYPFATEVM 51 +GK VTGA KGIG A A A + GA V G D A T+ Sbjct: 12 LAGKVAIVTGASKGIGAAIAKALADEGAAVVVNYASSKAGADAVVSAITEAGGRAVAVGG 71 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 DV+ AA ++ + RLD LVN +G+ + +++E +++ F NV G Sbjct: 72 DVSKAADAQRIVDTAIETYGRLDVLVNNSGVYEFAPIEAITEEHYRRQFDTNVFGVLLTT 131 Query: 112 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 171 Q + G +I+ ++S + Y +K A+ ++ + LEL +R N Sbjct: 132 QAAVKHL--GEGASIINISSVVTSITPPASAVYSGTKGAVDAITGVLALELGPRKIRVNA 189 Query: 172 VSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLAS 231 ++PG T+ + + E ++ G PLG++ P +IA+ +FLASD A Sbjct: 190 INPGMIVTEGTHSAGIIGSDLEAQVLGQ-------TPLGRLGEPNDIASVAVFLASDDAR 242 Query: 232 HITLQDIVVDGG 243 +T + +VV GG Sbjct: 243 WMTGEHLVVSGG 254 >4CQL-A nrPDB Length = 261 Score = 84.7 bits (208), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 77/257 (29%), Positives = 118/257 (45%), Gaps = 35/257 (13%) Query: 9 WVTGAGKGIGYATALAFVEAGAKVTG--FDQAFTQEQY-----PFATE----------VM 51 VTGAG GIG A ++ GA V D+A QE P + E Sbjct: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQA 74 Query: 52 DVADAAQVAQVCQRLLAETERLDALV-NAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 DV++A + +++ A R ++V + AGI + +S++DW + AVN+ G F L Sbjct: 75 DVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF-L 133 Query: 111 FQQTMNQFRRQRG--GAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVR 168 Q Q G G+I+ ++S +G + Y ASKA + L + EL G+R Sbjct: 134 VTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIR 193 Query: 169 CNVVSPGSTDTDMQRTL--WVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLA 226 CN V PG T M + + V D E IP+G + P+++A+ + FLA Sbjct: 194 CNSVLPGFIATPMTQKVPQKVVDKITEM------------IPMGHLGDPEDVADVVAFLA 241 Query: 227 SDLASHITLQDIVVDGG 243 S+ + +IT + V GG Sbjct: 242 SEDSGYITGTSVEVTGG 258 >4RZI-B nrPDB Length = 240 Score = 84.3 bits (207), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 68/238 (28%), Positives = 110/238 (46%), Gaps = 11/238 (4%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQR 65 K + VTG +GIG A E GAKV D A V +V D + Sbjct: 9 KVIVVTGGNRGIGAAIVKLLQEMGAKVAFTDLATDGGNTEALGVVANVTDLESMTAAAAE 68 Query: 66 LLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGA 125 + + + +V AGI + +L+ DW VN+ G + + ++ G+ Sbjct: 69 ITDKLGPVYGVVANAGITKDNFFPKLTPADWDAVLNVNLKGVAYSIKPFIEGMYERKAGS 128 Query: 126 IVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQRTL 185 IV ++S + +G + Y A+KA + + S+ E A GVR N V+PG DT+M TL Sbjct: 129 IVAISSISGERGNVGQTNYSATKAGVIGMMKSLAREGARYGVRANAVAPGFIDTEM--TL 186 Query: 186 WVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA-SHITLQDIVVDG 242 + +D E+ + IP + +P+EIA + FL S +A S++T + + V+G Sbjct: 187 AIREDIREKITKE--------IPFRRFGKPEEIAWAVAFLLSPVASSYVTGEVLRVNG 236 >1AHH-A nrPDB Length = 255 Score = 84.3 bits (207), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 71/254 (27%), Positives = 124/254 (48%), Gaps = 22/254 (8%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQY-----------PFATE 49 + GK +TGAG GIG A+ F AGA V D + FA Sbjct: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 Query: 50 VMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 D+ +++ + +++ ++D LVN AG D + D+++ + +NV F+ Sbjct: 67 C-DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFH 124 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 L Q + + GG I+T+ S AA I M++Y +SKAA L ++ +L +R Sbjct: 125 LSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N ++PG+ TD +++ ++ + E++ ++ P+ ++ +PQ+IAN LFL S Sbjct: 185 NGIAPGAILTDALKSV-ITPEIEQKMLQ--------HTPIRRLGQPQDIANAALFLCSPA 235 Query: 230 ASHITLQDIVVDGG 243 AS ++ Q + V GG Sbjct: 236 ASWVSGQILTVSGG 249 >2Q2Q-A nrPDB Length = 255 Score = 83.6 bits (205), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 77/254 (30%), Positives = 107/254 (42%), Gaps = 17/254 (6%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKV--TGFD---QAFTQEQYPFATEVMDVADAA 57 GK VTG+ GIG A AGA + GF A + V AD + Sbjct: 2 LKGKTALVTGSTSGIGLGIAQVLARAGANIVLNGFGDPAPALAEIARHGVKAVHHPADLS 61 Query: 58 QVAQVCQRLLAETER----LDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 VAQ+ + L A ER +D LVN AGI + +Q E W + A+N+ F+ + Sbjct: 62 DVAQI-EALFALAEREFGGVDILVNNAGIQHVAPVEQFPLESWDKIIALNLSAVFHGTRL 120 Query: 114 TMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 + R + G I+ +AS G +AY A+K + L VGLE A S V CN + Sbjct: 121 ALPGMRARNWGRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGLETATSNVTCNAIC 180 Query: 174 PGSTDTDM-QRTLWVSDDAEEQRIRGFGEQFKL---GIPLGKIARPQEIANTILFLASDL 229 PG T + Q+ + DD Q L P P+ + +LFL S+ Sbjct: 181 PGWVLTPLVQKQI---DDRAANGGDPLQAQHDLLAEKQPSLAFVTPEHLGELVLFLCSEA 237 Query: 230 ASHITLQDIVVDGG 243 S + VDGG Sbjct: 238 GSQVRGAAWNVDGG 251 >4IIV-A nrPDB Length = 267 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 71/250 (28%), Positives = 115/250 (46%), Gaps = 23/250 (9%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKV---TGFDQAFTQEQYPFATE--------VMDVA 54 ++V VTGA KGIG A A G + D A QE DVA Sbjct: 27 RSVLVTGASKGIGRAIARQLAADGFNIGVHYHRDAAGAQETLNAIVANGGNGRLLSFDVA 86 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 + Q +V + +A+ +V+ AGI R A LS +DW N+ +N+ Q Sbjct: 87 NREQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPALSNDDWDAVIHTNLDSFYNVIQPC 146 Query: 115 -MNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 M ++GG I+T++S + G Y A+KA + ++ +ELA + N ++ Sbjct: 147 IMPMIGARQGGRIITLSSVSGVMGNRGQVNYSAAKAGIIGATKALAIELAKRKITVNCIA 206 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 PG DT M + EE ++ E + IP+ ++ + +E+A +L SD+A ++ Sbjct: 207 PGLIDTGMI-------EMEESALK---EAMSM-IPMKRMGQAEEVAGLASYLMSDIAGYV 255 Query: 234 TLQDIVVDGG 243 T Q I ++GG Sbjct: 256 TRQVISINGG 265 >3R3S-A nrPDB Length = 294 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 71/256 (27%), Positives = 121/256 (47%), Gaps = 25/256 (9%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVM-------------D 52 + VTG GIG A A+A+ GA V + +E+ + + D Sbjct: 50 RKALVTGGDSGIGRAAAIAYAREGADV-AINYLPAEEEDAQQVKALIEECGRKAVLLPGD 108 Query: 53 VADAAQVAQVCQRLLAETERLDALVNAAGI-LRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 ++D + + + LD L AG + L+ E +QQTFAVNV F + Sbjct: 109 LSDESFARSLVHKAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQTFAVNVFALFWIT 168 Query: 112 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 171 Q+ + +G +I+T +S A+ P + Y A+KAA+ + + + ++A G+R N+ Sbjct: 169 QEAIPLL--PKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNI 226 Query: 172 VSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLAS 231 V+PG T +Q +S + +I FG+Q P+ + +P E+A ++LAS +S Sbjct: 227 VAPGPIWTALQ----ISGGQTQDKIPQFGQQ----TPMKRAGQPAELAPVYVYLASQESS 278 Query: 232 HITLQDIVVDGGSTLG 247 ++T + V GG LG Sbjct: 279 YVTAEVHGVCGGEHLG 294 >6CI9-A nrPDB Length = 259 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 72/255 (28%), Positives = 107/255 (41%), Gaps = 21/255 (8%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKV--TGFDQA--------FTQEQYPFATEVMD 52 G++ VTG KGIG A F AG V TG +Q + + D Sbjct: 7 LEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVRAD 66 Query: 53 VADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQ 112 V D + ++ LD + AGI G + L+ +D +Q VN G + Q Sbjct: 67 VTDPEDARRTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKGTVYIVQ 126 Query: 113 QTMNQFRRQ-RGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 171 + G +VT + T G S YGASKAA + +ELA + N Sbjct: 127 AALQALTASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAMELAPKKITINA 186 Query: 172 VSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLAS 231 V PG+ T+ ++ + + +Q IP G++ +I N LF A+D A+ Sbjct: 187 VLPGNIMTE----------GLDEMGQDYLDQMASAIPAGRLGSVADIGNAALFFATDEAA 236 Query: 232 HITLQDIVVDGGSTL 246 ++T Q +VVDGG L Sbjct: 237 YVTGQTLVVDGGQVL 251 >3VZS-A nrPDB Length = 257 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 63/250 (25%), Positives = 113/250 (45%), Gaps = 21/250 (8%) Query: 9 WVTGAGKGIGYATALAFVEAGAKVTG--------FDQAFTQEQ---YPFATEVMDVADAA 57 +VTG GIG A + G +V ++ Q++ + F +VAD Sbjct: 18 YVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGNVADWD 77 Query: 58 QVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQ 117 ++ +E +D L+N AGI R ++++ DW N+ FN+ +Q ++ Sbjct: 78 STKTAFDKVKSEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNVTKQVIDG 137 Query: 118 FRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGST 177 + G IV ++S + G + Y +KA L +++ E+A GV N VSPG Sbjct: 138 MADRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNTVSPGYI 197 Query: 178 DTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQD 237 TDM + + Q + ++ IP+ ++ P+EIA+ +L+S+ + T D Sbjct: 198 ATDMVKAI-------RQDVL---DKIVATIPVKRLGLPEEIASICAWLSSEESGFSTGAD 247 Query: 238 IVVDGGSTLG 247 ++GG +G Sbjct: 248 FSLNGGLHMG 257 >2ZAT-A nrPDB Length = 260 Score = 82.4 bits (202), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 70/255 (27%), Positives = 114/255 (44%), Gaps = 23/255 (9%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQV 62 K VT + GIG A A + GA V + QE + + V Sbjct: 12 LENKVALVTASTDGIGLAIARRLAQDGAHVVVSSR--KQENVDRTVATLQGEGLSVTGTV 69 Query: 63 C--------QRLLAETERL----DALV-NAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 C +RL+A L D LV NAA G ++E W + VNV Sbjct: 70 CHVGKAEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKATVL 129 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 + + + + ++ GG+++ V+S A+ P + Y SK AL L ++ +ELA +R Sbjct: 130 MTKAVVPEMEKRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIRV 189 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N ++PG T+ + LW+ D A + E K + + ++ P++ A + FL S+ Sbjct: 190 NCLAPGLIKTNFSQVLWM-DKARK-------EYMKESLRIRRLGNPEDCAGIVSFLCSED 241 Query: 230 ASHITLQDIVVDGGS 244 AS+IT + +VV GG+ Sbjct: 242 ASYITGETVVVGGGT 256 >3V2H-A nrPDB Length = 281 Score = 81.3 bits (199), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 71/258 (27%), Positives = 116/258 (44%), Gaps = 22/258 (8%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKV--TGFD-----QAFTQEQYPFA--TEVMDVADA 56 K +TG+ GIG A A +AGA + GF + T E + T + AD Sbjct: 26 KTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAGLSSGTVLHHPADM 85 Query: 57 AQVAQVCQRLLAETERL---DALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 + +++ + +R D LVN AG+ + + E W + AVN+ +F+ + Sbjct: 86 TKPSEIADMMAMVADRFGGADILVNNAGVQFVEKIEDFPVEQWDRIIAVNLSSSFHTIRG 145 Query: 114 TMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 + +++ G I+ +AS SAY A+K + L +V LE+A SGV N + Sbjct: 146 AIPPMKKKGWGRIINIASAHGLVASPFKSAYVAAKHGIMGLTKTVALEVAESGVTVNSIC 205 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKL------GIPLGKIARPQEIANTILFLAS 227 PG T + ++ R RG E+ + G P K +++A+ L+LA Sbjct: 206 PGYVLTPLVE----KQIPDQARTRGITEEQVINEVMLKGQPTKKFITVEQVASLALYLAG 261 Query: 228 DLASHITLQDIVVDGGST 245 D A+ IT + +DGG T Sbjct: 262 DDAAQITGTHVSMDGGWT 279 >4EGF-A nrPDB Length = 266 Score = 80.9 bits (198), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 88/260 (33%), Positives = 121/260 (46%), Gaps = 22/260 (8%) Query: 1 MDFSGKNVWVTGAGKGIGYATALA-------FVEAGAKVTGFDQAFTQEQYPFATEV--- 50 + GK +TGA KGIG A A V +G V+ D A F T+V Sbjct: 16 LRLDGKRALITGATKGIGADIARAFAAAGARLVLSGRDVSELDAARRALGEQFGTDVHTV 75 Query: 51 -MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 +D+A+ A++ +R LD LVN AGI + + T AVN+ A Sbjct: 76 AIDLAEPDAPAELARRAAEAFGGLDVLVNNAGISHPQPVVDTDPQLFDATIAVNLR-APA 134 Query: 110 LFQQTMNQ--FRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGV 167 L + + GGAI+TVAS AA P AY SKA L + EL G+ Sbjct: 135 LLASAVGKAMVAAGEGGAIITVASAAALAPLPDHYAYCTSKAGLVMATKVLARELGPHGI 194 Query: 168 RCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLAS 227 R N V P T+M + +W D+A+ + IPLG+ A P E+++ +++LAS Sbjct: 195 RANSVCPTVVLTEMGQRVW-GDEAKSAPMIAR-------IPLGRFAVPHEVSDAVVWLAS 246 Query: 228 DLASHITLQDIVVDGGSTLG 247 D AS I DI VDGG T+G Sbjct: 247 DAASMINGVDIPVDGGYTMG 266 >1H5Q-A nrPDB Length = 265 Score = 80.9 bits (198), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 72/270 (26%), Positives = 124/270 (45%), Gaps = 45/270 (16%) Query: 1 MDFSGKNVWVTGAGKGIG-----------------YATALAFVEAGAKVTGFDQAFTQEQ 43 + F K + VTG +GIG Y +A VE KV G + + Sbjct: 10 ISFVNKTIIVTGGNRGIGLAFTRAVAAAGANVAVIYRSAADAVEVTEKV-GKEFGVKTKA 68 Query: 44 YPFATEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVN 103 Y DV++ V + Q++ A+ + L+ AG+ + +L+ ED+ + VN Sbjct: 69 YQ-----CDVSNTDIVTKTIQQIDADLGPISGLIANAGVSVVKPATELTHEDFAFVYDVN 123 Query: 104 VGGAFNLFQQTMNQF-RRQRGGAIVTVASDAAHTPRIGMSA---------YGASKAALKS 153 V G FN + + ++Q+ G+IV +S ++ I S+ Y +SKAA + Sbjct: 124 VFGVFNTCRAVAKLWLQKQQKGSIVVTSSMSSQI--INQSSLNGSLTQVFYNSSKAACSN 181 Query: 154 LALSVGLELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIA 213 L + E A +G+R N +SPG +TD + +++IR + IPL + A Sbjct: 182 LVKGLAAEWASAGIRVNALSPGYVNTDQTAHM-------DKKIR---DHQASNIPLNRFA 231 Query: 214 RPQEIANTILFLASDLASHITLQDIVVDGG 243 +P+E+ + L SD A+++T + +DGG Sbjct: 232 QPEEMTGQAILLLSDHATYMTGGEYFIDGG 261 >3OIC-A nrPDB Length = 258 Score = 80.9 bits (198), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 69/255 (27%), Positives = 115/255 (45%), Gaps = 23/255 (9%) Query: 5 GKNVWVTGAGKGIGYATALAFVEAG---------AKVTGFDQAFTQEQYPFATEVM--DV 53 K VTG+ +G+G A A+ E G +K + A E+ V+ +V Sbjct: 4 NKCALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALETAEEIEKLGVKVLVVKANV 63 Query: 54 ADAAQVAQVCQRLLAETERLDALVN--AAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 A++ ++ Q++ RLD VN A+G+LR +L + W T +N Sbjct: 64 GQPAKIKEMFQQIDETFGRLDVFVNNAASGVLR--PVMELEETHWDWTMNINAKALLFCA 121 Query: 112 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 171 Q+ + GG IV+++S + + G SKAAL++L + +EL+ + N Sbjct: 122 QEAAKLMEKNGGGHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAVELSPKQIIVNA 181 Query: 172 VSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLAS 231 VS G+ DTD + +D E + P G++ +++ +T+ FL S A Sbjct: 182 VSGGAIDTDALKHFPNRED--------LLEDARQNTPAGRMVEIKDMVDTVEFLVSSKAD 233 Query: 232 HITLQDIVVDGGSTL 246 I Q I+VDGG +L Sbjct: 234 MIRGQTIIVDGGRSL 248 >5YSS-A nrPDB Length = 256 Score = 80.5 bits (197), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 69/256 (26%), Positives = 113/256 (44%), Gaps = 17/256 (6%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKV--TGF------DQAFTQEQYPFATEVMD 52 M+ +GK VTG+ GIG A +AGA + GF A Q D Sbjct: 1 MNLTGKTALVTGSTSGIGLGIAQVLAQAGATLILNGFGDVDAAKDAVAQYGKTPGYHGAD 60 Query: 53 VADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQ 112 ++D AQ+A + + +E +D L+N AGI + + + W A+N+ F+ + Sbjct: 61 LSDEAQIADMMRYAESEFGGVDILINNAGIQHVSPIETFPVDKWNAIIAINLSSVFHTTR 120 Query: 113 QTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVV 172 + R + G I+ +AS SAY A+K + L ++ LE A + + CN + Sbjct: 121 LALPGMRARNWGRIINIASVHGLVASKEKSAYVAAKHGVVGLTKTIALETAQTEITCNAL 180 Query: 173 SPGSTDTDM---QRTLWVSDDAEEQRIRG--FGEQFKLGIPLGKIARPQEIANTILFLAS 227 PG T + Q +++ AE + R E+ P + P+++ N LFL S Sbjct: 181 CPGWVLTPLVQQQIDKRIAEGAEPEAARDALLAEKQ----PSREFVTPEQLGNLALFLCS 236 Query: 228 DLASHITLQDIVVDGG 243 D A+ + +DGG Sbjct: 237 DGAAQVRGVAWNMDGG 252 >1X1T-A nrPDB Length = 260 Score = 80.5 bits (197), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 73/269 (27%), Positives = 107/269 (39%), Gaps = 38/269 (14%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKV--TGFDQAFTQEQY------PFATEVM--- 51 GK VTG+ GIG A A GA + GF A E+ +V+ Sbjct: 2 LKGKVAVVTGSTSGIGLGIATALAAQGADIVLNGFGDAAEIEKVRAGLAAQHGVKVLYDG 61 Query: 52 -DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 D++ V + + + R+D LVN AGI + E W A+N+ F+ Sbjct: 62 ADLSKGEAVRGLVDNAVRQMGRIDILVNNAGIQHTALIEDFPTEKWDAILALNLSAVFHG 121 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 + ++Q G I+ +AS SAY A+K + LE AG G+ N Sbjct: 122 TAAALPHMKKQGFGRIINIASAHGLVASANKSAYVAAKHGVVGFTKVTALETAGQGITAN 181 Query: 171 VVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGI--------------PLGKIARPQ 216 + PG WV E++I E K G+ P + P+ Sbjct: 182 AICPG----------WVRTPLVEKQISALAE--KNGVDQETAARELLSEKQPSLQFVTPE 229 Query: 217 EIANTILFLASDLASHITLQDIVVDGGST 245 ++ T +FLASD A+ IT + VDGG T Sbjct: 230 QLGGTAVFLASDAAAQITGTTVSVDGGWT 258 >3W8F-A nrPDB Length = 260 Score = 80.1 bits (196), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 71/267 (26%), Positives = 106/267 (39%), Gaps = 34/267 (12%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKV--TGFDQAFTQEQYPFATEVM--------- 51 GK VTG+ GIG A A +AGA V GF Q E+ E Sbjct: 2 LKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVKAYYLN 61 Query: 52 -DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 D++DA + LD LVN AGI ++ + W A+N+ F+ Sbjct: 62 ADLSDAQATRDFIAKAAEALGGLDILVNNAGIQHTAPIEEFPVDKWNAIIALNLSAVFHG 121 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 + ++Q G I+ +AS + SAY A+K + L LE AG G+ CN Sbjct: 122 TAAALPIMQKQGWGRIINIASAHGLVASVNKSAYVAAKHGVVGLTKVTALENAGKGITCN 181 Query: 171 VVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGI------------PLGKIARPQEI 218 + PG WV E++I +Q + I P + P+++ Sbjct: 182 AICPG----------WVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQPSLQFVTPEQL 231 Query: 219 ANTILFLASDLASHITLQDIVVDGGST 245 +FL+S A +T + +DGG T Sbjct: 232 GGAAVFLSSAAADQMTGTTLSLDGGWT 258 >1YXM-A nrPDB Length = 303 Score = 79.7 bits (195), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 63/256 (24%), Positives = 111/256 (43%), Gaps = 30/256 (11%) Query: 10 VTGAGKGIGYATALAFVEAGAKVTGFDQAFT---------QEQYPFATEV------MDVA 54 VTG GIG A +E G+ V + Q P + ++ Sbjct: 23 VTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIR 82 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 + +V + + L +++ LVN G + + +S + W N+ G F + + Sbjct: 83 NEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAV 142 Query: 115 MNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSP 174 + + ++ GG+IV + + + + GA++A + +L S+ LE A SG+R N V+P Sbjct: 143 YSSWMKEHGGSIVNIIVPTKAGFPLAVHS-GAARAGVYNLTKSLALEWACSGIRINCVAP 201 Query: 175 GSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLG----IPLGKIARPQEIANTILFLASDLA 230 G + + +G+ F G IP +I P+E+++ + FL S A Sbjct: 202 GV----------IYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAA 251 Query: 231 SHITLQDIVVDGGSTL 246 S IT Q + VDGG +L Sbjct: 252 SFITGQSVDVDGGRSL 267 >3OML-A nrPDB Length = 613 Score = 79.3 bits (194), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 63/190 (33%), Positives = 90/190 (47%), Gaps = 16/190 (8%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQE----QYPFATEVMD---- 52 + + G+ VTGAG G+G AL F E GAKV D T A V+D Sbjct: 15 LRYDGRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRK 74 Query: 53 -----VADAAQV---AQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNV 104 VAD V A+V + + R+D LVN AGILR + + S++DW V++ Sbjct: 75 AGGEAVADYNSVIDGAKVIETAIKAFGRVDILVNNAGILRDRSLVKTSEQDWNLVNDVHL 134 Query: 105 GGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAG 164 G+F Q ++Q G I+ +S++ G Y A+K L LA +V +E A Sbjct: 135 KGSFKCTQAAFPYMKKQNYGRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLANTVAIEGAR 194 Query: 165 SGVRCNVVSP 174 + V CNV+ P Sbjct: 195 NNVLCNVIVP 204 >3A28-C nrPDB Length = 258 Score = 79.3 bits (194), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 64/200 (32%), Positives = 98/200 (49%), Gaps = 12/200 (6%) Query: 51 MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 +DV D A + D LVN AGI ++ ++++ED +Q ++VNV F Sbjct: 60 LDVTDKANFDSAIDEAAEKLGGFDVLVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFG 119 Query: 111 FQQTMNQFRRQ--RGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVR 168 Q +F +G I + A I +SAY +K A++ L + ELA G Sbjct: 120 IQAASRKFDELGVKGKIINAASIAAIQGFPI-LSAYSTTKFAVRGLTQAAAQELAPKGHT 178 Query: 169 CNVVSPGSTDTDMQRTLWVSDDAEEQRIRG--FGEQFK---LGIPLGKIARPQEIANTIL 223 N +PG T M W DAE +I G GE FK I LG+ + P+++A + Sbjct: 179 VNAYAPGIVGTGM----WEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVS 234 Query: 224 FLASDLASHITLQDIVVDGG 243 FLAS+ ++++T Q ++VDGG Sbjct: 235 FLASENSNYVTGQVMLVDGG 254 >3RWB-A nrPDB Length = 247 Score = 78.2 bits (191), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 72/254 (28%), Positives = 115/254 (45%), Gaps = 27/254 (10%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD----------QAFTQEQYPFATEVMD 52 +GK VTGA +GIG A A GA V D + ++ A D Sbjct: 4 LAGKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASIGKKARAIAA---D 60 Query: 53 VADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQ 112 ++D V + + A T +D LVN A I+ A D + + W++ VN+ G F + + Sbjct: 61 ISDPGSVKALFAEIQALTGGIDILVNNASIVPFVAWDDVDLDHWRKIIDVNLTGTFIVTR 120 Query: 113 QTMNQFRRQ-RGGAIVTVASDA--AHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 +Q R + G ++++AS+ A TP M+AY A+K + ++ EL + Sbjct: 121 AGTDQMRAAGKAGRVISIASNTFFAGTPN--MAAYVAAKGGVIGFTRALATELGKYNITA 178 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N V+PG ++D + + GF E + + +P+ IA+ + FLASD Sbjct: 179 NAVTPGLIESDGVKA------SPHNEAFGFVEMLQ---AMKGKGQPEHIADVVSFLASDD 229 Query: 230 ASHITLQDIVVDGG 243 A IT Q + VD G Sbjct: 230 ARWITGQTLNVDAG 243 >5IZ4-A nrPDB Length = 271 Score = 76.6 bits (187), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 77/259 (29%), Positives = 117/259 (45%), Gaps = 29/259 (11%) Query: 10 VTGAGKGIGYATALAFVEAGAKVT--GFDQAFTQEQYPFATEVM------------DVAD 55 +TG+ GIG ATAL F +AG V FD + T++ + DV Sbjct: 19 ITGSASGIGAATALRFAQAGWSVAIGNFDDS-TRDAASTVEALCRDAGAQTLIFDADVGK 77 Query: 56 AAQVAQVCQRLLAETERLDALVNAAGILRM---GATDQLSKEDWQQTFAVNVGGAFNLFQ 112 A + + +R+DAL+N AG R+ A DQ+ ++++ + VN+ G + + + Sbjct: 78 DADCRHAVDMVASRWQRIDALINCAGTTRVIPHNAFDQIDDFEFERVYRVNLIGLYQMTR 137 Query: 113 QTMNQFRRQ----RGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVR 168 + R R ++V V+S A AY ASK A+ +L LS+ LA +R Sbjct: 138 AAVPLLRESASATRSTSVVNVSSLAGLNGTGSSIAYAASKGAVNTLTLSLARNLA-PHIR 196 Query: 169 CNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASD 228 N ++PG D + L V D A G + PL +++RP EIA FL + Sbjct: 197 VNALAPGMVDDGL--LLRVLDAAAYD---GVLSRMTESAPLKRVSRPAEIAELAWFLTAH 251 Query: 229 LASHITLQDIVVDGGSTLG 247 A IT Q I + G LG Sbjct: 252 -APAITGQVIAAENGLLLG 269 >4DBZ-A nrPDB Length = 281 Score = 76.3 bits (186), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 74/250 (29%), Positives = 111/250 (44%), Gaps = 19/250 (7%) Query: 10 VTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQ-RLLA 68 VTGA GIG A + G +V F A +E + + A + C R + Sbjct: 31 VTGATSGIGLEIARRLGKEGLRV--FVCARGEEGLRTTLKELREAGVEADGRTCDVRSVP 88 Query: 69 ETERL-----------DALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQ 117 E E L D LVN AG GAT +L+ E W N+ G F + +Q + Sbjct: 89 EIEALVAAVVERYGPVDVLVNNAGRPGGGATAELADELWLDVVETNLTGVFRVTKQVLKA 148 Query: 118 F-RRQRG-GAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPG 175 +RG G IV +AS + + Y ASK + ++GLELA +G+ N V PG Sbjct: 149 GGMLERGTGRIVNIASTGGKQGLVHAAPYSASKHGVVGFTKALGLELARTGITVNAVCPG 208 Query: 176 STDTDMQRTL--WVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 +T M ++ SD E F ++ +P+G+ +P E+A + +L A+ + Sbjct: 209 FVETPMAASVREHYSDIWEVSTEEAF-DRITARVPIGRYVQPSEVAEMVAYLIGPGAAAV 267 Query: 234 TLQDIVVDGG 243 T Q + V GG Sbjct: 268 TAQALNVCGG 277 >4CR6-A nrPDB Length = 271 Score = 74.7 bits (182), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 78/254 (30%), Positives = 116/254 (45%), Gaps = 22/254 (8%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQA----FTQEQYPFATEV-MDVADAA 57 +GK VTGA GIG AT A++ GA V D A T+ + P A + D+AD A Sbjct: 13 LAGKAAIVTGAAGGIGRATVEAYLREGASVVAMDLAPRLAATRYEEPGAIPIACDLADRA 72 Query: 58 QVAQVCQRLLAETERLDALVNAAGILRMGATD--QLSKEDWQQTFAVNVGGAFNLFQQTM 115 + +A LD LV A G L+ G + LS DW + VN+ G F + Sbjct: 73 AIDAAMADAVARLGGLDILV-AGGALKGGTGNFLDLSDADWDRYVDVNMTGTFLTCRAGA 131 Query: 116 NQF------RRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 + R I+T+ S + +AY A+K + L ++ ++LA G+ Sbjct: 132 RAMVAAGAGKDGRSARIITIGSVNSFMAEPEAAAYVAAKGGVAMLTRAMAVDLARHGILV 191 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N+++PG D T + E R+ EQ + LG+ P+E+A +FLA D Sbjct: 192 NMIAPGPVDVTGNNTGY-----SEPRL---AEQVLDEVALGRPGLPEEVATAAVFLAEDG 243 Query: 230 ASHITLQDIVVDGG 243 +S IT I +DGG Sbjct: 244 SSFITGSTITIDGG 257 >4FC7-A nrPDB Length = 277 Score = 74.3 bits (181), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 63/256 (24%), Positives = 111/256 (43%), Gaps = 26/256 (10%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQ--------------EQYPFATEVM 51 K ++TG G GIG+ A F+ G ++ + P + M Sbjct: 28 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLS---M 84 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 DV V + L E R+D L+N A + LS ++ ++ G FN+ Sbjct: 85 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 144 Query: 112 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 171 + +F R GG IV + + + + G++KAA+ ++ + +E +R N Sbjct: 145 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 204 Query: 172 VSPGS-TDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 230 ++PG + T+ R L + ++ PL ++ EIA+++L+LAS LA Sbjct: 205 LAPGPISGTEGLRRLGGPQASLSTKVTAS--------PLQRLGNKTEIAHSVLYLASPLA 256 Query: 231 SHITLQDIVVDGGSTL 246 S++T +V DGG+ L Sbjct: 257 SYVTGAVLVADGGAWL 272 >3U5T-A nrPDB Length = 267 Score = 73.6 bits (179), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 71/255 (27%), Positives = 113/255 (44%), Gaps = 30/255 (11%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKV--TGFDQAFTQEQYPFATEVM---------D 52 + K VTGA +GIG A A G V +A E+ E D Sbjct: 26 TNKVAIVTGASRGIGAAIAARLASDGFTVVINYAGKAAAAEEVAGKIEAAGGKALTAQAD 85 Query: 53 VADAAQVAQVCQRLLAETER----LDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAF 108 V+D A V +RL A E +D LVN AGI+ + + + + AVN+ G F Sbjct: 86 VSDPAAV----RRLFATAEEAFGGVDVLVNNAGIMPLTTIAETGDAVFDRVIAVNLKGTF 141 Query: 109 NLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVR 168 N ++ + R GG I+ +++ Y A+KA ++++ + EL G + Sbjct: 142 NTLREAAQRLRV--GGRIINMSTSQVGLLHPSYGIYAAAKAGVEAMTHVLSKELRGRDIT 199 Query: 169 CNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASD 228 N V+PG T TD L++ ++E R ++F PL ++ PQ+IA + FLA Sbjct: 200 VNAVAPGPTATD----LFLEGKSDEVR-----DRFAKLAPLERLGTPQDIAGAVAFLAGP 250 Query: 229 LASHITLQDIVVDGG 243 + + Q + +GG Sbjct: 251 DGAWVNGQVLRANGG 265 >3T7C-A nrPDB Length = 299 Score = 73.6 bits (179), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 75/275 (27%), Positives = 118/275 (42%), Gaps = 37/275 (13%) Query: 5 GKNVWVTGAGKGIGYATALAFVEAGAKVTGFD--QAFTQEQYPFATEVMDVADAA-QVAQ 61 GK ++TGA +G G + A+ GA + D + + P +T D+A+ QV Sbjct: 28 GKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPD-DLAETVRQVEA 86 Query: 62 VCQRLLA---ETERLDALVNAA--GILRMGATD----------------QLSKEDWQQTF 100 + +R++A + DA+ A G+ ++G D ++ + W+ Sbjct: 87 LGRRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRMDPKTWRDMI 146 Query: 101 AVNVGGAFNLFQQTMNQFRR-QRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVG 159 VN+ GA+ + + +RGG+IV +S + Y ASK L L ++ Sbjct: 147 DVNLNGAWITARVAIPHIMAGKRGGSIVFTSSIGGLRGAENIGNYIASKHGLHGLMRTMA 206 Query: 160 LELAGSGVRCNVVSPGSTDTDM----QRTLWVSDDAEEQRIRGF----GEQFKLGIPLGK 211 LEL +R N+V P S T M D E + F + L IP Sbjct: 207 LELGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFQVASRQMHVLPIPY-- 264 Query: 212 IARPQEIANTILFLASDLASHITLQDIVVDGGSTL 246 P +I+N ILFL SD A +IT + VDGG+ L Sbjct: 265 -VEPADISNAILFLVSDDARYITGVSLPVDGGALL 298 >1DOH-A nrPDB Length = 283 Score = 73.6 bits (179), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 64/264 (24%), Positives = 120/264 (45%), Gaps = 27/264 (10%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKV-TGFDQAFTQEQYPFATEVMDVADAAQV-- 59 GK VTGAG+GIG A+ G KV + + + A + +DAA V Sbjct: 27 LEGKVALVTGAGRGIGREMAMELGRRGCKVIVNYANSTESAEEVVAAIKKNGSDAACVKA 86 Query: 60 ----AQVCQRLLAETER----LDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 + R+ E + LD + + +G++ G ++ E++ + F +N G F + Sbjct: 87 NVGVVEDIVRMFEEAVKIFGKLDIVCSNSGVVSFGHVKDVTPEEFDRVFTINTRGQFFVA 146 Query: 112 QQTMNQFRRQRGGAIVTVAS---DAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVR 168 ++ + GG ++ + S A P+ + Y SK A+++ A + +++A + Sbjct: 147 REAYKHL--EIGGRLILMGSITGQAKAVPK--HAVYSGSKGAIETFARCMAIDMADKKIT 202 Query: 169 CNVVSPGSTDTDMQRTLWVS-----DDAEEQRIRGFGE-QFKLGIPLGKIARPQEIANTI 222 NVV+PG TDM + ++ + + + Q+ PL ++ P +IA + Sbjct: 203 VNVVAPGGIKTDMYHAVCREYIPNGENLSNEEVDEYAAVQWS---PLRRVGLPIDIARVV 259 Query: 223 LFLASDLASHITLQDIVVDGGSTL 246 FLAS+ +T + I +DGG+ + Sbjct: 260 CFLASNDGGWVTGKVIGIDGGACM 283 >2GDZ-A nrPDB Length = 267 Score = 72.8 bits (177), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 73/245 (29%), Positives = 111/245 (45%), Gaps = 33/245 (13%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD---------QAFTQEQY-PFATEVM-- 51 +GK VTGA +GIG A A A + GAKV D +A EQ+ P T + Sbjct: 6 NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLFIQC 65 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 DVAD Q+ ++++ RLD LVN AG+ ++++W++T +N+ + Sbjct: 66 DVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVISGT 117 Query: 112 QQTMNQFRRQRGGA---IVTVASDAAHTPRIGMSAYGASKAALKSLALSVGL--ELAGSG 166 ++ +Q GG I+ ++S A P Y ASK + S L L SG Sbjct: 118 YLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSG 177 Query: 167 VRCNVVSPGSTDTDMQRTLWVSDDAEE---QRIRGFGEQFKLGIPLGKIARPQEIANTIL 223 VR N + PG +T + ++ + EE Q I + + K I I P IAN ++ Sbjct: 178 VRLNAICPGFVNTAILESI----EKEENMGQYIE-YKDHIKDMIKYYGILDPPLIANGLI 232 Query: 224 FLASD 228 L D Sbjct: 233 TLIED 237 >3RKU-A nrPDB Length = 287 Score = 72.8 bits (177), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 64/219 (29%), Positives = 95/219 (43%), Gaps = 28/219 (12%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAG-------------AKVTGFDQAFTQEQYPFA-- 47 + K V +TGA GIG ATAL ++EA K+ + QE +P A Sbjct: 31 LAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQE-FPNAKV 89 Query: 48 -TEVMDVADAAQVAQVCQRLLAETERLDALVNAAG-ILRMGATDQLSKEDWQQTFAVNVG 105 +D+ A ++ + L E + +D LVN AG L Q++ ED Q F NV Sbjct: 90 HVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQIATEDIQDVFDTNVT 149 Query: 106 GAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGS 165 N+ Q + F+ + G IV + S A S Y ASK A+ + S+ EL + Sbjct: 150 ALINITQAVLPIFQAKNSGDIVNLGSIAGRDAYPTGSIYCASKFAVGAFTDSLRKELINT 209 Query: 166 GVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFK 204 +R +++PG +T+ R RG EQ K Sbjct: 210 KIRVILIAPGLVETEFSLV----------RYRGNEEQAK 238 >4HP8-A nrPDB Length = 247 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 68/246 (27%), Positives = 108/246 (43%), Gaps = 14/246 (5%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQV 62 G+ VTGA G+G A A+ AGA+V + E + A A + Sbjct: 7 LEGRKALVTGANTGLGQAIAVGLAAAGAEVVCAARRAPDETLDIIAKDGGNASALLI-DF 65 Query: 63 CQRLLAETERLDA----LVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQF 118 L A+ DA LVN AGI+R + + S+ DW + VN+ F Q + Sbjct: 66 ADPLAAKDSFTDAGFDILVNNAGIIRRADSVEFSELDWDEVMDVNLKALFFTTQAFAKEL 125 Query: 119 -RRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGST 177 + R G +V +AS + I + +Y A+K + L + E A G+ N ++PG Sbjct: 126 LAKGRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTKLLANEWAAKGINVNAIAPGYI 185 Query: 178 DTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQD 237 +T+ L A+ R + E+ IP G+ ++IA +FL+S A ++ Sbjct: 186 ETNNTEAL----RADAARNKAILER----IPAGRWGHSEDIAGAAVFLSSAAADYVHGAI 237 Query: 238 IVVDGG 243 + VDGG Sbjct: 238 LNVDGG 243 >2AE2-A nrPDB Length = 260 Score = 71.2 bits (173), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 60/253 (23%), Positives = 107/253 (42%), Gaps = 16/253 (6%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKV-------TGFDQAFTQ---EQYPFATEVM 51 + G VTG +GIGY GA V + TQ + + V Sbjct: 6 NLEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKVEASVC 65 Query: 52 DVADAAQVAQVCQRLLAETE-RLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 D++ ++ ++ + +L+ LVN AGI+ + ED+ ++N A++L Sbjct: 66 DLSSRSERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINFEAAYHL 125 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 + G +V ++S + + YGA+K A+ L + E A +R N Sbjct: 126 SVLAHPFLKASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAFEWAKDNIRVN 185 Query: 171 VVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 230 V PG T + + + D +++ + ++ L ++ P+E+A + FL A Sbjct: 186 GVGPGVIATSLVE-MTIQDPEQKENLNKLIDR----CALRRMGEPKELAAMVAFLCFPAA 240 Query: 231 SHITLQDIVVDGG 243 S++T Q I VDGG Sbjct: 241 SYVTGQIIYVDGG 253 >3U4C-A nrPDB Length = 281 Score = 71.2 bits (173), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 66/259 (25%), Positives = 116/259 (44%), Gaps = 21/259 (8%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVT----GFDQAFTQEQ-----YPFATEVM-- 51 S + +V GA +GIG A AL + + D + ++ +P A+ ++ Sbjct: 21 MSKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVLA 80 Query: 52 -DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSK---EDWQQTFAVNVGGA 107 D++D A + Q++ ++ RLD L+N + GA D ED TF Sbjct: 81 GDMSDQHTRAGIFQKIESQCGRLDVLINN---IPGGAPDTFDNCNIEDMTATFTQKTVAY 137 Query: 108 FNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGV 167 + ++ + ++ G I+ + + P M AAL + + ++ ++LA + Sbjct: 138 IDAIKRASSLMKQNEFGRIINIVGNLWKEPGANMFTNSMMNAALINASKNISIQLAPHNI 197 Query: 168 RCNVVSPGSTDTDMQRTLWVSDDAEEQRI--RGFGEQFKLGIPLGKIARPQEIANTILFL 225 N ++PG TD +V + ++ I + EQ GIP+ ++ +E A FL Sbjct: 198 TVNCLNPGFIATDRYHQ-FVENVMKKNSISKQKAEEQIASGIPMKRVGSAEETAALAAFL 256 Query: 226 ASDLASHITLQDIVVDGGS 244 AS+ AS+IT Q I DGGS Sbjct: 257 ASEEASYITGQQISADGGS 275 >4GKB-A nrPDB Length = 258 Score = 71.2 bits (173), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 68/216 (31%), Positives = 101/216 (46%), Gaps = 13/216 (6%) Query: 34 GFDQAFTQEQYPFATEV-MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLS 92 F A Q Q P AT + +++ D AQ + +A RLD LVN AG+ G Sbjct: 45 AFLDALAQRQ-PRATYLPVELQDDAQCRDAVAQTIATFGRLDGLVNNAGV-NDGIGLDAG 102 Query: 93 KEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALK 152 ++ + + N+ + + + + RG AIV ++S A T + S Y ASK A Sbjct: 103 RDAFVASLERNLIHYYAMAHYCVPHLKATRG-AIVNISSKTAVTGQGNTSGYCASKGAQL 161 Query: 153 SLALSVGLELAGSGVRCNVVSPGSTDTDMQRTLWVS--DDAEEQRIRGFGEQFKLGIPLG 210 +L + L GVR N V P T + R W++ +D E + + +PLG Sbjct: 162 ALTREWAVALREHGVRVNAVIPAEVMTPLYRN-WIATFEDPEAKL-----AEIAAKVPLG 215 Query: 211 -KIARPQEIANTILFLASDLASHITLQDIVVDGGST 245 + P EIA+T +FL S ASH T + + VDGG T Sbjct: 216 RRFTTPDEIADTAVFLLSPRASHTTGEWLFVDGGYT 251 >2EW8-A nrPDB Length = 249 Score = 69.3 bits (168), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 65/242 (26%), Positives = 101/242 (41%), Gaps = 16/242 (6%) Query: 10 VTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYP--------FATEVMDVADAAQVAQ 61 +TG GIG A A F GA + D E T DV+ V Sbjct: 12 ITGGANGIGRAIAERFAVEGADIAIADLVPAPEAEAAIRNLGRRVLTVKCDVSQPGDVEA 71 Query: 62 VCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQ 121 +++++ R D LVN AGI + D+L+ E W++TF +NV F + + + +R Sbjct: 72 FGKQVISTFGRCDILVNNAGIYPLIPFDELTFEQWKKTFEINVDSGFLMAKAFVPGMKRN 131 Query: 122 RGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDM 181 G I+ + S + Y ++KAA ++ +L G+ N ++P + Sbjct: 132 GWGRIINLTSTTYWLKIEAYTHYISTKAANIGFTRALASDLGKDGITVNAIAPS-----L 186 Query: 182 QRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVD 241 RT A + IP ++ P ++ FLASD AS IT Q + VD Sbjct: 187 VRTATTEASALSAMFDVLPNMLQ-AIP--RLQVPLDLTGAAAFLASDDASFITGQTLAVD 243 Query: 242 GG 243 GG Sbjct: 244 GG 245 >5JS6-A nrPDB Length = 274 Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 61/231 (26%), Positives = 112/231 (48%), Gaps = 13/231 (5%) Query: 24 AFVEAGAKVTGFDQAFT-----QEQYPFATEVM-DVADAAQVAQVCQRLLAETERLDALV 77 AFV +GA+V D+ + +++ P A ++ DV V + + RLD +V Sbjct: 30 AFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVV 89 Query: 78 NAAGILRMGA-TDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHT 136 N AG ++ S + ++Q +N+ G + L + + R+ +G ++ ++S Sbjct: 90 NNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGN-VINISSLVGAI 148 Query: 137 PRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRI 196 + Y A+K A+ ++ ++ L+ + GVR N +SPG+ T LW A Sbjct: 149 GQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTP----LWEELAALMPDP 204 Query: 197 RGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDGGSTLG 247 R + L PLG++ +P E+ +FLAS+ A+ T +++V GG+ LG Sbjct: 205 RATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIELLVTGGAELG 254 >3UVE-A nrPDB Length = 286 Score = 68.9 bits (167), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 73/278 (26%), Positives = 116/278 (41%), Gaps = 39/278 (14%) Query: 5 GKNVWVTGAGKGIGYATALAFVEAGAKVTGFD-----QAFTQEQYPFATEVMDVADAAQV 59 GK +VTGA +G G + A+ + GA + D +A + A+ D+A+ A + Sbjct: 11 GKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDLAETADL 70 Query: 60 AQVCQRLLAETE---------------------RLDALVNAAGILRMGAT-DQLSKEDWQ 97 + R + E RLD +V AGI G T D+ S+EDW Sbjct: 71 VKGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNGGDTLDKTSEEDWT 130 Query: 98 QTFAVNVGGAFNLFQQTM-NQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLAL 156 + +N+ G + + + + RGG+I+ +S Y A+K + L Sbjct: 131 EMIDINLAGVWKTVKAGVPHMIAGGRGGSIILTSSVGGLKAYPHTGHYVAAKHGVVGLMR 190 Query: 157 SVGLELAGSGVRCNVVSPGSTDTDMQRT-----LWVSD--DAEEQRIRGFGEQFK-LGIP 208 + G+EL +R N V P T M ++ D + + + F L IP Sbjct: 191 AFGVELGQHMIRVNSVHPTHVKTPMLHNEGTFKMFRPDLENPGPDDMAPICQMFHTLPIP 250 Query: 209 LGKIARPQEIANTILFLASDLASHITLQDIVVDGGSTL 246 P +I+N +LF ASD A +IT + +D GS L Sbjct: 251 W---VEPIDISNAVLFFASDEARYITGVTLPIDAGSCL 285 >3E9N-A nrPDB Length = 245 Score = 67.0 bits (162), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 50/159 (31%), Positives = 75/159 (47%), Gaps = 15/159 (9%) Query: 67 LAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAI 126 L + +D LV+AA + R + S +W +NV L +Q + R G + Sbjct: 70 LKNLDHVDTLVHAAAVARDTTIEAGSVAEWHAHLDLNVIVPAELSRQLLPALRAA-SGCV 128 Query: 127 VTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQRTLW 186 + + S A + P G + Y ASK AL+ LA + E A +G+R + VSPG T+T M + L Sbjct: 129 IYINSGAGNGPHPGNTIYAASKHALRGLADAFRKEEANNGIRVSTVSPGPTNTPMLQGLM 188 Query: 187 VSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFL 225 S G F+ I + P+EIAN I F+ Sbjct: 189 DSQ----------GTNFRPEIYI----EPKEIANAIRFV 213 >1HXH-A nrPDB Length = 253 Score = 67.0 bits (162), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 75/261 (28%), Positives = 113/261 (43%), Gaps = 30/261 (11%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKV--TGFDQAFTQ-------EQYPFA-TEVMD 52 GK VTG G+G + GAKV + ++A Q E+ F +V Sbjct: 4 LQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGERSMFVRHDVSS 63 Query: 53 VADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQ 112 AD V QR L L+ LVN AGIL G + ED+ + +N F Q Sbjct: 64 EADWTLVMAAVQRRLGT---LNVLVNNAGILLPGDMETGRLEDFSRLLKINTESVFIGCQ 120 Query: 113 QTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLEL--AGSGVRCN 170 Q + + + GG+I+ +AS ++ P + Y ASKAA+ +L + L G +R N Sbjct: 121 QGIAAMK-ETGGSIINMASVSSWLPIEQYAGYSASKAAVSALTRAAALSCRKQGYAIRVN 179 Query: 171 VVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIP----LGKIARPQEIANTILFLA 226 + P T M + +G ++ L P G+ P+ IA +LFLA Sbjct: 180 SIHPDGIYTPMMQA---------SLPKGVSKEMVLHDPKLNRAGRAYMPERIAQLVLFLA 230 Query: 227 SDLASHITLQDIVVDGGSTLG 247 SD +S ++ ++ D S LG Sbjct: 231 SDESSVMSGSELHAD-NSILG 250 >4TRR-A nrPDB Length = 269 Score = 66.6 bits (161), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 76/264 (28%), Positives = 119/264 (45%), Gaps = 31/264 (11%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQE-QYPFATEV---------- 50 + +GK VTGA GIG AL +AGA V D Q+ A E+ Sbjct: 11 NLNGKTAVVTGAASGIGKEIALELAKAGAAVAIAD--LNQDGANAVADEINKAGGKAIGV 68 Query: 51 -MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 MDV + V ++ +D LV+ AGI + + S DW++ A++V GAF Sbjct: 69 AMDVTNEEAVNTGIDKVAEAFGSVDILVSNAGIQIVNPIENYSFADWKKMQAIHVDGAFL 128 Query: 110 LFQQTMNQ-FRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVR 168 + + ++ RGG ++ + S +H SAY +K L LA + E A VR Sbjct: 129 TTKAALKHMYKDDRGGVVIYMGSVHSHEASPLKSAYVTAKHGLLGLARVLAKEGAKHNVR 188 Query: 169 CNVVSPGSTDTDM--------QRTLWVSDDAEEQRIRGFGEQFKLGIPL-GKIARPQEIA 219 +VV PG T + + L +S EE+ I+ + LG + G Q++A Sbjct: 189 SHVVCPGFVRTPLVDKQIPEQAKELGIS---EEEVIK----KVMLGNTVDGVFTTVQDVA 241 Query: 220 NTILFLASDLASHITLQDIVVDGG 243 T+LFL++ ++ +T Q +V G Sbjct: 242 QTVLFLSAFPSAALTGQSFIVSHG 265 >2BGM-A nrPDB Length = 278 Score = 66.2 bits (160), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 51/197 (25%), Positives = 93/197 (47%), Gaps = 8/197 (4%) Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLS--KEDWQQTFAVNVGGAFN 109 DV V + +A+ +LD + G+L L ED+++ +NV GAF Sbjct: 72 DVTKDEDVRNLVDTTIAKHGKLDIMFGNVGVLSTTPYSILEAGNEDFKRVMDINVYGAFL 131 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMS-AYGASKAALKSLALSVGLELAGSGVR 168 + + + G+IV AS ++ T G+S Y A+K A+ L S+ EL G+R Sbjct: 132 VAKHAARVMIPAKKGSIVFTASISSFTAGEGVSHVYTATKHAVLGLTTSLCTELGEYGIR 191 Query: 169 CNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASD 228 N VSP + + ++ D + + + K G + R +++A+ + +LA D Sbjct: 192 VNCVSPYIVASPLLTDVFGVDSSRVEELAHQAANLK-----GTLLRAEDVADAVAYLAGD 246 Query: 229 LASHITLQDIVVDGGST 245 + +++ ++V+DGG T Sbjct: 247 ESKYVSGLNLVIDGGYT 263 >3GDF-A nrPDB Length = 267 Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 63/261 (24%), Positives = 112/261 (42%), Gaps = 27/261 (10%) Query: 1 MDFSGKNVWVTGAG--KGIGYATALAFVEAGAKVT--------GFDQAFTQEQYPFATEV 50 + GK V VTGA KG+G A E GA V G ++ + + + + Sbjct: 16 LSLKGKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKTYGIKA 75 Query: 51 MDVADAAQVAQVCQRLL----AETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGG 106 + C++L+ A+ ++DA + AG S E W V++ G Sbjct: 76 KAYKCQVDSYESCEKLVKDVVADFGQIDAFIANAGATADSGILDGSVEAWNHVVQVDLNG 135 Query: 107 AFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGM--SAYGASKAALKSLALSVGLELAG 164 F+ + + F+ + G++V AS + H ++Y +KA +A S+ E Sbjct: 136 TFHCAKAVGHHFKERGTGSLVITASMSGHIANFPQEQTSYNVAKAGCIHMARSLANEWR- 194 Query: 165 SGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILF 224 R N +SPG DT + + E Q++ + IP+G+ +E+ ++ Sbjct: 195 DFARVNSISPGYIDTGLSDFV----PKETQQL------WHSMIPMGRDGLAKELKGAYVY 244 Query: 225 LASDLASHITLQDIVVDGGST 245 ASD +++ T D+++DGG T Sbjct: 245 FASDASTYTTGADLLIDGGYT 265 >3PXX-A nrPDB Length = 287 Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 75/282 (26%), Positives = 113/282 (40%), Gaps = 48/282 (17%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQE--QYPFAT---------EV---- 50 K V VTG +G G + A+ E GA + FD E +YP AT EV Sbjct: 11 KVVLVTGGARGQGRSHAVKLAEEGADIILFDICHDIETNEYPLATSRDLEEAGLEVEKTG 70 Query: 51 -------MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVN 103 +DV D A V++ +AE +LD +V AGI +GA L + + F V+ Sbjct: 71 RKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANAGICPLGA--HLPVQAFADAFDVD 128 Query: 104 VGGAFNLFQQTMNQFRRQRGGAIVTVASDA-----------AHTPRIGMSAYGASKAALK 152 G N + G +I+T S A G + Y +K + Sbjct: 129 FVGVINTVHAALPYL--TSGASIITTGSVAGLIAAAQPPGAGGPQGPGGAGYSYAKQLVD 186 Query: 153 SLALSVGLELAGSGVRCNVVSPGSTDTDMQRTL-----WVSDDAEEQR---IRGFGEQFK 204 S L + +LA +R NV+ P + +TDM + + D R + F Sbjct: 187 SYTLQLAAQLAPQSIRANVIHPTNVNTDMLNSAPMYRQFRPDLEAPSRADALLAFPAMQA 246 Query: 205 LGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDGGSTL 246 + P +I+N + FLASD + ++T VD G+ L Sbjct: 247 MPTPY---VEASDISNAVCFLASDESRYVTGLQFKVDAGAML 285 >1BDB-A nrPDB Length = 277 Score = 65.1 bits (157), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 61/239 (25%), Positives = 100/239 (41%), Gaps = 14/239 (5%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQA---FTQEQYPFATEVM----DV 53 M G+ V +TG G+G A FV GAKV D++ + + V+ DV Sbjct: 1 MKLKGEAVLITGGASGLGRALVDRFVAEGAKVAVLDKSAERLAELETDHGDNVLGIVGDV 60 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMG-ATDQLSKED----WQQTFAVNVGGAF 108 Q R +A ++D L+ AGI A L +E + + F +NV G Sbjct: 61 RSLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHINVKGYI 120 Query: 109 NLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVR 168 + + + RG I T+ S+A P G Y A+K A+ L + ELA VR Sbjct: 121 HAVKACLPALVASRGNVIFTI-SNAGFYPNGGGPLYTAAKHAIVGLVRELAFELAPY-VR 178 Query: 169 CNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLAS 227 N V G ++D++ + ++ + K +P+G++ +E +F A+ Sbjct: 179 VNGVGSGGINSDLRGPSSLGMGSKAISTVPLADMLKSVLPIGRMPEVEEYTGAYVFFAT 237 >4DRY-A nrPDB Length = 281 Score = 65.1 bits (157), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 47/135 (34%), Positives = 65/135 (48%), Gaps = 3/135 (2%) Query: 50 VMDVADAAQVAQVCQRLLAETERLDALVNAAGI-LRMGATDQLSKEDWQQTFAVNVGGAF 108 V DV D QVA + + AE RLD LVN AG + ++++ E W A N+ GAF Sbjct: 89 VCDVGDPDQVAALFAAVRAEFARLDLLVNNAGSNVPPVPLEEVTFEQWNGIVAANLTGAF 148 Query: 109 NLFQQTMNQFRRQ--RGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSG 166 Q + Q RGG I+ S +A TPR + Y A+K A+ L S L+ Sbjct: 149 LCTQHAFRMMKAQTPRGGRIINNGSISAQTPRPNSAPYTATKHAITGLTKSTALDGRMHD 208 Query: 167 VRCNVVSPGSTDTDM 181 + C + G+ TDM Sbjct: 209 IACGQIDIGNAATDM 223 >3ZV3-A nrPDB Length = 281 Score = 64.7 bits (156), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 65/243 (26%), Positives = 103/243 (42%), Gaps = 22/243 (9%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATE-------VMDV 53 M +G+ +TG G+G A FV GA+V D++ + + V DV Sbjct: 1 MKLTGEVALITGGASGLGRALVDRFVAEGARVAVLDKSAERLRELEVAHGGNAVGVVGDV 60 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKED-----WQQTFAVNVGGAF 108 + +R LA ++D L+ AGI ED + F VNV G Sbjct: 61 RSLQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDIFHVNVKGYI 120 Query: 109 NLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVR 168 + + + RG + T+ S+A P G Y A+K A+ L + ELA VR Sbjct: 121 HAVKACLPALVSSRGSVVFTI-SNAGFYPNGGGPLYTATKHAVVGLVRQMAFELA-PHVR 178 Query: 169 CNVVSPGSTDTDMQ--RTLWVSDDAEEQRIRG--FGEQFKLGIPLGKIARPQEIANTILF 224 N V+PG +TD++ +L +S EQ I + K +P+G++ +E +F Sbjct: 179 VNGVAPGGMNTDLRGPSSLGLS----EQSISSVPLADMLKSVLPIGRMPALEEYTGAYVF 234 Query: 225 LAS 227 A+ Sbjct: 235 FAT 237 >2X9N-A nrPDB Length = 288 Score = 64.3 bits (155), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 78/272 (28%), Positives = 111/272 (40%), Gaps = 49/272 (18%) Query: 10 VTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRLLAE 69 VTGA K IG A A+ + G +V + A E+ + + A VCQ L Sbjct: 28 VTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNK--ERSNTAVVCQADLTN 85 Query: 70 TE------------------RLDALVNAAGILRMGATDQLSKEDWQ--QTFAVNVG---- 105 + R D LVN A Q ED +T V Sbjct: 86 SNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDNSNGKTVETQVAELIG 145 Query: 106 -GAFNLFQQTMNQFRRQRGG---------AIVTVASDAAHTPRIGMSAYGASKAALKSLA 155 A F TM+ +RQ+G +IV + P + S Y K AL L Sbjct: 146 TNAIAPFLLTMSFAQRQKGTNPNCTSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLT 205 Query: 156 LSVGLELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKI-AR 214 S LELA G+R N V+PG + L V+ EE+ ++++ +PLG+ A Sbjct: 206 QSAALELAPYGIRVNGVAPGVS------LLPVAMGEEEK------DKWRRKVPLGRREAS 253 Query: 215 PQEIANTILFLASDLASHITLQDIVVDGGSTL 246 ++IA+ ++FL S A +IT I VDGG +L Sbjct: 254 AEQIADAVIFLVSGSAQYITGSIIKVDGGLSL 285 >4RGB-A nrPDB Length = 294 Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 65/271 (23%), Positives = 112/271 (41%), Gaps = 34/271 (12%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPF---------------- 46 G+ V++TGA +G G + A+ E GA + G D + P+ Sbjct: 23 LDGRVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEETARLVE 82 Query: 47 --ATEVM----DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTF 100 E++ DV D A + +V + + +D ++ AG++ ++ + E + Sbjct: 83 KTGQEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLTNPDERDASEALRLGL 142 Query: 101 AVNVGGAFNLFQQTMNQFR-RQRGGAIVTVASDAAHTP----RIGMSAYGASKAALKSLA 155 + + G +N FQ + + R +GG ++ +S A R G AY SK A+ L Sbjct: 143 DIMLIGVWNTFQVAIPHMKERGQGGNLIATSSMIALLDLTDGRGGTDAYLTSKLAITGLV 202 Query: 156 LSVGLELAGSGVRCNVVSPGSTDTDM---QRTLWVSDDAEEQRIRGFGEQFKLGIPLGKI 212 S L LA +R N V+P + T M L+ + + +P + Sbjct: 203 RSYALMLAADRIRVNGVAPTNCSTPMITENPALFKVIEENPHLVNA----MSTALPDFPM 258 Query: 213 ARPQEIANTILFLASDLASHITLQDIVVDGG 243 P++++N ILFL SD T + VD G Sbjct: 259 IEPRDVSNAILFLISDAGRSFTGSVLKVDAG 289 >5ILO-A nrPDB Length = 271 Score = 62.8 bits (151), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 60/215 (27%), Positives = 93/215 (43%), Gaps = 29/215 (13%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAG-AKVTGFD-----QAFTQEQYPFATEV-----M 51 F GKN VTG GIG + + AG AKV D + F + + T+ M Sbjct: 13 FRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKM 72 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 DVA+ V + + +D +VN AGI + +D Q+T VN+GG N Sbjct: 73 DVANKKGVEATYEEIAKTFGNIDIVVNVAGI--------FNDKDVQRTLLVNLGGIINST 124 Query: 112 QQTMNQFRRQ---RGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLE--LAGSG 166 + + +GG +V ++S P + YGA+KA + + + E SG Sbjct: 125 LSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRSG 184 Query: 167 VRCNVVSPGSTDTDM-----QRTLWVSDDAEEQRI 196 ++ V PG+T TDM ++ ++ E RI Sbjct: 185 IKFVTVCPGATMTDMFTNFTEKIIFPETSDETYRI 219 >2NWQ-A nrPDB Length = 272 Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 62/244 (25%), Positives = 106/244 (43%), Gaps = 22/244 (9%) Query: 8 VWVTGAGKGIGYATALAFVEAGAKV--TGFDQAFTQE---QYPFATEVM----DVADAAQ 58 +++TGA G G A A F EAG + TG + Q + T V+ DV D A Sbjct: 24 LFITGATSGFGEACARRFAEAGWSLVLTGRREERLQALAGELSAKTRVLPLTLDVRDRAA 83 Query: 59 VAQVCQRLLAETERLDALVNAAGI-LRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQ 117 ++ L E L L+N AG+ L +DW N+ G + + + Sbjct: 84 MSAAVDNLPEEFATLRGLINNAGLALGTDPAQSCDLDDWDTMVDTNIKGLLYSTRLLLPR 143 Query: 118 FRRQRGGA-IVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGS 176 GA IV + S A P G YG +KA ++ +L++ +L G+GVR + PG Sbjct: 144 LIAHGAGASIVNLGSVAGKWPYPGSHVYGGTKAFVEQFSLNLRCDLQGTGVRVTNLEPGL 203 Query: 177 TDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQ 236 +++ + D A + + + P+ +P++IA TI ++ + A H+ + Sbjct: 204 CESEFSLVRFGGDQAR------YDKTYAGAHPI----QPEDIAETIFWIMNQPA-HLNIN 252 Query: 237 DIVV 240 + + Sbjct: 253 SLEI 256 >2O23-A nrPDB Length = 265 Score = 61.2 bits (147), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 61/195 (31%), Positives = 87/195 (44%), Gaps = 19/195 (9%) Query: 10 VTGAGKGIGYATALAFVEAGAKVTGFDQAFT----QEQYPFATEVMDVADAAQVAQVCQR 65 +TG G+G ATA V GA D + Q + V AD V Sbjct: 17 ITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTA 76 Query: 66 L-LAETE--RLDALVNAAGILRMGATDQLSK------EDWQQTFAVNVGGAFNLFQQT-- 114 L LA+ + R+D VN AGI T L K ED+Q+ VN+ G FN+ + Sbjct: 77 LALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAG 136 Query: 115 -MNQFRRQRGG---AIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 M Q +GG I+ AS AA ++G +AY ASK + + L + +LA G+R Sbjct: 137 EMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVM 196 Query: 171 VVSPGSTDTDMQRTL 185 ++PG T + +L Sbjct: 197 TIAPGLFGTPLLTSL 211 >5EJ2-A nrPDB Length = 308 Score = 59.3 bits (142), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 67/274 (24%), Positives = 110/274 (40%), Gaps = 33/274 (12%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQ--YPFATEVMDVADAAQVAQ 61 +GK +++GA +G G + A+ + GA + D E YP +T D+A+ A + + Sbjct: 36 AGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTP-EDLAETADLVK 94 Query: 62 VCQRLLAETE---------------------RLDALVNAAGILRMG-ATDQLSKEDWQQT 99 R + + RLD +V AG+ G ++ WQ Sbjct: 95 DLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTDGRKLHKIRDNVWQDM 154 Query: 100 FAVNVGGAFNLFQQTMNQ-FRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSV 158 +N+ G ++ + + RGG+IV +S Y A+K + L + Sbjct: 155 IDINLTGVWHTVKAGVPHVLSGGRGGSIVLTSSVGGRKAYPNTGHYIAAKHGVIGLMRAF 214 Query: 159 GLELAGSGVRCNVVSPGSTDTDM----QRTLWVSDDAEEQRIRGFGE--QFKLGIPLGKI 212 +EL +R N V P T M Q D E F Q +P+ + Sbjct: 215 AVELGPHMIRVNAVLPTQVSTTMVMNDQTFRLFRPDLENPGPDDFAPISQMMHTLPVPWV 274 Query: 213 ARPQEIANTILFLASDLASHITLQDIVVDGGSTL 246 +I+N +LFLASD + ++T + VD GS L Sbjct: 275 -DASDISNAVLFLASDESRYVTGVSLPVDAGSLL 307 >1E3W-A nrPDB Length = 261 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 57/195 (29%), Positives = 85/195 (43%), Gaps = 19/195 (9%) Query: 10 VTGAGKGIGYATALAFVEAGAKVTGFD----QAFTQEQYPFATEVMDVADAAQVAQVCQR 65 +TG G+G +TA V GA D + T+ + + A+ +V Sbjct: 15 ITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAA 74 Query: 66 LLAETE---RLDALVNAAGILRMGATDQLSK------EDWQQTFAVNVGGAFNLFQQT-- 114 L E R+D VN AGI T K ED+Q+ VN+ G FN+ + Sbjct: 75 LTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVAG 134 Query: 115 -MNQFRRQRGG---AIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 M Q +GG I+ AS AA ++G +AY ASK + + L + +LA G+R Sbjct: 135 VMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVV 194 Query: 171 VVSPGSTDTDMQRTL 185 ++PG T + TL Sbjct: 195 TIAPGLFATPLLTTL 209 >3KZV-A nrPDB Length = 254 Score = 58.5 bits (140), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 51/191 (26%), Positives = 93/191 (48%), Gaps = 13/191 (6%) Query: 5 GKNVWVTGAGKGIGYATA--LAFVEAGAKVTGFDQAFT-----QEQY--PFATEVMDVAD 55 GK + VTG +GIG + L ++ V G ++ +E+Y F V D+ + Sbjct: 2 GKVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARSEAPLKKLKEKYGDRFFYVVGDITE 61 Query: 56 AAQVAQVCQRLLAETERLDALVNAAGILR-MGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 + + Q+ + ++D+LV AG+L + +++ W++ + +N +L Sbjct: 62 DSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNEIDVNAWKKLYDINFFSIVSLVGIA 121 Query: 115 MNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSP 174 + + ++ G +V V+SDA + AYG+SKAAL A+++ E V+ V+P Sbjct: 122 LPELKKTNGN-VVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANE--ERQVKAIAVAP 178 Query: 175 GSTDTDMQRTL 185 G DTDMQ + Sbjct: 179 GIVDTDMQVNI 189 >1W73-A nrPDB Length = 302 Score = 57.0 bits (136), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 8/193 (4%) Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGG-AFNL 110 DV D V L+ + ++N A + T++LS W+ + + G AF Sbjct: 84 DVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFVT 143 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 + + Q+G A +++ + A T + ++KA +++++ S+ E G+R N Sbjct: 144 LEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFN 203 Query: 171 VVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 230 V+ PG T + E+ + G IP G++ +E+AN FL SD A Sbjct: 204 VIQPGPIKTKGAFSRLDPTGTFEKEMIG-------RIPCGRLGTVEELANLAAFLCSDYA 256 Query: 231 SHITLQDIVVDGG 243 S I I DGG Sbjct: 257 SWINGAVIKFDGG 269 >2DKN-A nrPDB Length = 255 Score = 57.0 bits (136), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 75/263 (28%), Positives = 102/263 (38%), Gaps = 48/263 (18%) Query: 8 VWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRLL 67 + +TG+ GIG A AG V G D+ + +T A V C +L Sbjct: 4 IAITGSASGIGAALKELLARAGHTVIGIDRGQADIEADLSTPGGRETAVAAVLDRCGGVL 63 Query: 68 AETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAIV 127 D LV AG+ A L AVN G L R + A V Sbjct: 64 ------DGLVCCAGVGVTAANSGL-------VVAVNYFGVSALLDGLAEALSRGQQPAAV 110 Query: 128 TVASDAAHTP---RIGMS-----------------------AYGASKAALKSLALSVGLE 161 V S AA P + M AY SK A+ LA ++ Sbjct: 111 IVGSIAATQPGAAELPMVEAMLAGDEARAIELAEQQGQTHLAYAGSKYAVTCLARRNVVD 170 Query: 162 LAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGI-PLGKIARPQEIAN 220 AG GVR NVV+PG+ +T L + A+ + +GE + + PLG+ + P+E+A Sbjct: 171 WAGRGVRLNVVAPGAVET----PLLQASKADPR----YGESTRRFVAPLGRGSEPREVAE 222 Query: 221 TILFLASDLASHITLQDIVVDGG 243 I FL AS I + VDGG Sbjct: 223 AIAFLLGPQASFIHGSVLFVDGG 245 >4M89-A nrPDB Length = 261 Score = 56.2 bits (134), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 70/262 (26%), Positives = 114/262 (43%), Gaps = 29/262 (11%) Query: 5 GKNVWVTG--AGKGIGYATALAFVEAGAK------VTGFDQAFTQEQYPFATEVM---DV 53 GK + +TG + + I Y A A E GA+ V ++ + +E++ DV Sbjct: 6 GKKILITGMISERSIAYGIAKACREQGAELAFTYVVDKLEERVRKMAAELDSELVFRCDV 65 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGAT-----DQLSKEDWQQTFAVNVGGAF 108 A ++ QV L + LD LV++ G A D +S+E + ++ A+ Sbjct: 66 ASDDEINQVFADLGKHWDGLDGLVHSIGFAPKEALSGDFLDSISREAFNTAHEIS---AY 122 Query: 109 NL--FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSG 166 +L + R R AIV ++ A + G +KA+L++ L G Sbjct: 123 SLPALAKAARPMMRGRNSAIVALSYLGAVRAIPNYNVMGMAKASLEAGIRFTAACLGKEG 182 Query: 167 VRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLA 226 +RCN +S G +TL S A+ ++ G PL + +E+ NT FL Sbjct: 183 IRCNGISAGPI-----KTLAASGIADFGKLLGHVAAHN---PLRRNVTIEEVGNTAAFLL 234 Query: 227 SDLASHITLQDIVVDGGSTLGA 248 SDL+S IT + VDGG ++ A Sbjct: 235 SDLSSGITGEITYVDGGYSINA 256 >2YW9-A nrPDB Length = 261 Score = 55.1 bits (131), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 72/268 (26%), Positives = 108/268 (40%), Gaps = 45/268 (16%) Query: 1 MDFSGKNVWVTGAG--KGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQ 58 +D SGK V G + +G+A A EAGA+V A + + E +A+A Sbjct: 4 VDLSGKKALVMGVTNQRSLGFAIAAKLKEAGAEV-----ALSYQAERLRPEAEKLAEALG 58 Query: 59 VAQVCQRLLAETERLDALVNAAGILR-MGATDQL-------------------SKEDWQQ 98 A + + + + E LDAL AG+ G D L ++DW Sbjct: 59 GALLFRADVTQDEELDALF--AGVKEAFGGLDYLVHAIAFAPREAMEGRYIDTRRQDWLL 116 Query: 99 TFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSV 158 V+ + ++ R GG IVT+ A+ + +KAAL++ + Sbjct: 117 ALEVSAYSLVAVARRAEPLLRE--GGGIVTLTYYASEKVVPKYNVMAIAKAALEASVRYL 174 Query: 159 GLELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKL---GIPLGKIARP 215 EL GVR N +S G T R+ I GF + + PL + Sbjct: 175 AYELGPKGVRVNAISAGPVRTVAARS-----------IPGFTKMYDRVAQTAPLRRNITQ 223 Query: 216 QEIANTILFLASDLASHITLQDIVVDGG 243 +E+ N LFL S LAS IT + + VD G Sbjct: 224 EEVGNLGLFLLSPLASGITGEVVYVDAG 251 >1FJH-A nrPDB Length = 257 Score = 53.9 bits (128), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 72/266 (27%), Positives = 109/266 (40%), Gaps = 52/266 (19%) Query: 8 VWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRLL 67 + ++G GIG AT AG ++ G D A + D++ A Q +L Sbjct: 4 IVISGCATGIGAATRKVLEAAGHQIVGID-------IRDAEVIADLSTAEGRKQAIADVL 56 Query: 68 AETER-LDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAI 126 A+ + +D LV AG +G ++ +VN GA L + ++ A Sbjct: 57 AKCSKGMDGLVLCAG---LGPQTKV----LGNVVSVNYFGATELMDAFLPALKKGHQPAA 109 Query: 127 VTVASDA-AH-----TP----------------------RIGMSAYGASKAALKSLALSV 158 V ++S A AH P + G AY SK AL Sbjct: 110 VVISSVASAHLAFDKNPLALALEAGEEAKARAIVEHAGEQGGNLAYAGSKNALTVAVRKR 169 Query: 159 GLELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQF-KLGIPLGKIARPQE 217 +GVR N ++PG+T+T + + A Q R +GE K P+G+ A P E Sbjct: 170 AAAWGEAGVRLNTIAPGATETPLLQ-------AGLQDPR-YGESIAKFVPPMGRRAEPSE 221 Query: 218 IANTILFLASDLASHITLQDIVVDGG 243 +A+ I FL S AS++ IV+DGG Sbjct: 222 MASVIAFLMSPAASYVHGAQIVIDGG 247 >5I9N-A nrPDB Length = 276 Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 65/255 (25%), Positives = 110/255 (43%), Gaps = 26/255 (10%) Query: 5 GKNVWVTG--AGKGIGYATALAFVEAGAKVT------GFDQAFTQEQYPFATEVM---DV 53 GK + +TG + + I Y A A GA++ F T+ F +E++ DV Sbjct: 6 GKRILLTGLLSNRSIAYGIAKACKREGAELAFTYVGDRFKDRITEFAAEFGSELVFPCDV 65 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGAT-----DQLSKEDWQQTFAVNVGGAF 108 AD AQ+ + L + LD LV++ G A D L++E+++ ++ Sbjct: 66 ADDAQIDALFASLKTHWDSLDGLVHSIGFAPREAIAGDFLDGLTRENFRIAHDISAYSFP 125 Query: 109 NLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVR 168 L + + +++T++ A + G +KAAL++ + + L GVR Sbjct: 126 ALAKAALPMLSDD--ASLLTLSYLGAERAIPNYNTMGLAKAALEASVRYLAVSLGAKGVR 183 Query: 169 CNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASD 228 N +S G +TL S +I F E PL + +++ N FL SD Sbjct: 184 VNAISAGPI-----KTLAASGIKSFGKILDFVES---NSPLKRNVTIEQVGNAGAFLLSD 235 Query: 229 LASHITLQDIVVDGG 243 LAS +T + + VD G Sbjct: 236 LASGVTAEVMHVDSG 250 >1P33-A nrPDB Length = 289 Score = 52.8 bits (125), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 43/138 (31%), Positives = 67/138 (48%), Gaps = 15/138 (10%) Query: 112 QQTMNQFRRQRGGA--IVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 Q+ + QRG + IV + P +G + Y +K AL+ L S LELA +R Sbjct: 161 QRVADTRAEQRGTSYSIVNMVDAMTSQPLLGYTMYTMAKEALEGLTRSAALELASLQIRV 220 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPL-GKIARPQEIANTILFLASD 228 N VSPG L V D ++ E ++ +PL + + +E+++ ++FL S Sbjct: 221 NGVSPG---------LSVLPDDMPFSVQ---EDYRRKVPLYQRNSSAEEVSDVVIFLCSP 268 Query: 229 LASHITLQDIVVDGGSTL 246 A +IT I VDGG +L Sbjct: 269 KAKYITGTCIKVDGGYSL 286 >3U9L-A nrPDB Length = 324 Score = 50.4 bits (119), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 50/193 (25%), Positives = 92/193 (47%), Gaps = 18/193 (9%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKV-------TGFDQAFTQEQYPFA------ 47 M S K + +TGA G G TA A AG +V G + + + FA Sbjct: 1 MVMSKKIILITGASSGFGRLTAEALAGAGHRVYASMRDIVGRNASNVEAIAGFARDNDVD 60 Query: 48 --TEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVG 105 T +DV V + +++ E R+D L++ AG + G + + E + + + +NV Sbjct: 61 LRTLELDVQSQVSVDRAIDQIIGEDGRIDVLIHNAGHMVFGPAEAFTPEQFAELYDINVL 120 Query: 106 GAFNLFQQTMNQFRRQRGGAIVTV--ASDAAHTPRIGMSAYGASKAALKSLALSVGLELA 163 + + + RRQ+ G ++ + +S A TP ++ Y A+KAA+ ++A+ EL+ Sbjct: 121 STQRVNRAALPHMRRQKHGLLIWISSSSSAGGTPPY-LAPYFAAKAAMDAIAVQYARELS 179 Query: 164 GSGVRCNVVSPGS 176 G+ +++ PG+ Sbjct: 180 RWGIETSIIVPGA 192 >5TF4-A nrPDB Length = 274 Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 54/228 (23%), Positives = 99/228 (43%), Gaps = 14/228 (6%) Query: 23 LAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRLLAETERLDALVNAAGI 82 LAF G + + +E F DV+D+A + V + + +LD LV+A G Sbjct: 41 LAFTYQGEAMKKRVEPLAEEVKGFVCGHCDVSDSASIDAVFNTIEKKWGKLDFLVHAIGF 100 Query: 83 LRM----GATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPR 138 G +S+ ++ T ++V L ++ + GG+I+T+ A Sbjct: 101 SDKEELSGRYVDISESNFMMTMNISVYSLTALTKRA--EKLMSDGGSILTLTYYGAEKVV 158 Query: 139 IGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRG 198 + G +KAAL++ + ++L +R N +S G +TL S + + I Sbjct: 159 PNYNVMGVAKAALEASVKYLAVDLGPKHIRVNAISAGPI-----KTLAASGIGDFRYILK 213 Query: 199 FGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDGGSTL 246 + E PL + +E+ ++ L+L SDL+ +T + VD G + Sbjct: 214 WNEY---NAPLRRTVTIEEVGDSALYLLSDLSRSVTGEVHHVDSGYNI 258 >3PPI-A nrPDB Length = 281 Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 37/126 (29%), Positives = 65/126 (51%), Gaps = 15/126 (11%) Query: 120 RQRG--GAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGST 177 R+ G GA+V AS A + +IG +AY A+KA + L ++ +L+ +G+R N ++PG+ Sbjct: 161 RENGERGALVLTASIAGYEGQIGQTAYAAAKAGVIGLTIAAARDLSSAGIRVNTIAPGTM 220 Query: 178 DTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGK-IARPQEIANTILFLASDLASHITLQ 236 T + ++ EE + F IP K + P E A+ FL ++ +I + Sbjct: 221 KTPIMESVG-----EEALAK-----FAANIPFPKRLGTPDEFADAAAFLLTN--GYINGE 268 Query: 237 DIVVDG 242 + +DG Sbjct: 269 VMRLDG 274 >5O3Z-A nrPDB Length = 263 Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 51/200 (25%), Positives = 86/200 (43%), Gaps = 5/200 (2%) Query: 51 MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 +D D A V + + + R D LV +AG+ + Q D+ + VN+ G F L Sbjct: 64 VDATDEASVEALARAVDETFGRADLLVYSAGVAKAAPITQFRLTDFDLSLQVNLVGYF-L 122 Query: 111 FQQTMNQFRRQRG--GAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVR 168 + ++ + G G I+ + S + S Y A+K L S+ L+LA G+ Sbjct: 123 CSREFSKLMIRDGIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDLAEYGIT 182 Query: 169 CNVVSPGSTDTDMQRTLWVSDDAEEQRI--RGFGEQFKLGIPLGKIARPQEIANTILFLA 226 + + G+ + AE+ I + +PL + Q++ N +LF A Sbjct: 183 VHSLMLGNLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPLKRGCDYQDVLNVLLFYA 242 Query: 227 SDLASHITLQDIVVDGGSTL 246 SD A++ T Q I V GG + Sbjct: 243 SDKAAYCTGQSINVTGGQVM 262 >4J3F-A nrPDB Length = 280 Score = 49.3 bits (116), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 60/256 (23%), Positives = 104/256 (40%), Gaps = 24/256 (9%) Query: 3 FSGKNVWVTG--AGKGIGYATALAFVEAGAK-----VTGFD---QAFTQEQYPFATEVMD 52 +GK + +TG + K I Y A A GA+ V F + E P A D Sbjct: 24 LAGKKILITGLLSNKSIAYGIAKAMHREGAELAFTYVGQFKDRVEKLCAEFNPAAVLPCD 83 Query: 53 VADAAQVAQVCQRLLAETERLDALVNAAGI-----LRMGATDQLSKEDWQQTFAVNVGGA 107 V ++ + L + LDA+V++ L D +++E + ++ + Sbjct: 84 VISDQEIKDLFVELGKVWDGLDAIVHSIAFAPRDQLEGNFIDCVTREGFSIAHDIS-AYS 142 Query: 108 FNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGV 167 F + + R ++V + A + G +KA+L++ L L G+ Sbjct: 143 FAALAKEGRSMMKNRNASMVALTYIGAEKAMPSYNTMGVAKASLEATVRYTALALGEDGI 202 Query: 168 RCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLAS 227 + N VS G +TL S + +++ + PL K E+ NT+ FL S Sbjct: 203 KVNAVSAGPI-----KTLAASGISNFKKMLDYNAMVS---PLKKNVDIMEVGNTVAFLCS 254 Query: 228 DLASHITLQDIVVDGG 243 D+A+ IT + + VD G Sbjct: 255 DMATGITGEVVHVDAG 270 >4DA9-A nrPDB Length = 280 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 68/252 (26%), Positives = 104/252 (41%), Gaps = 33/252 (13%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEA-GAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQV 62 SG ++ +TG G G A +A + GA+V F +A D+AD + Sbjct: 52 SGFDIAITGIGDAEGVAPVIAELSGLGARVI-FLRA-------------DLADLSSHQAT 97 Query: 63 CQRLLAETERLDALVNAAGILRMGATD--QLSKEDWQQTFAVNVGGAFNLFQQTMNQF-- 118 ++AE R+D LVN AGI + D L E++ VN+ G Q + Sbjct: 98 VDAVVAEFGRIDCLVNNAGIASIVRDDFLDLKPENFDTIVGVNLRGTVFFTQAVLKAMLA 157 Query: 119 ---RRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPG 175 R R +I+ + S +A Y SKA L + + + L LA +G+ V PG Sbjct: 158 SDARASR--SIINITSVSAVMTSPERLDYCMSKAGLAAFSQGLALRLAETGIAVFEVRPG 215 Query: 176 STDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITL 235 +DM T VS + G +P+ + P++I N + LA T Sbjct: 216 IIRSDM--TAAVSGKYDGLIESGL-------VPMRRWGEPEDIGNIVAGLAGGQFGFATG 266 Query: 236 QDIVVDGGSTLG 247 I DGG ++G Sbjct: 267 SVIQADGGLSIG 278 >2BFA-A nrPDB Length = 288 Score = 47.8 bits (112), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 38/132 (28%), Positives = 62/132 (46%), Gaps = 19/132 (14%) Query: 120 RQRGG--AIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGST 177 + RG +I+ + + P +G + Y +K AL+ L S LELA +R N V PG + Sbjct: 168 KHRGTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLS 227 Query: 178 DT--DMQRTLWVSDDAEEQRIRGFGEQFKLGIPL-GKIARPQEIANTILFLASDLASHIT 234 DM +W E + +PL + + E+++ ++FL S A +IT Sbjct: 228 VLVDDMPPAVW--------------EGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYIT 273 Query: 235 LQDIVVDGGSTL 246 + VDGG +L Sbjct: 274 GTCVKVDGGYSL 285 >4NR0-A nrPDB Length = 273 Score = 47.8 bits (112), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 59/231 (25%), Positives = 98/231 (42%), Gaps = 22/231 (9%) Query: 23 LAFVEAGAKVTGFDQAFTQE--QYPFATEVMDVADAAQVAQVCQRLLAETERLDALVNAA 80 LAF K+ G + F P DVAD +Q+ V L + LD +V++ Sbjct: 35 LAFTYQNDKLRGRVEEFASGWGSRPELCFPCDVADDSQIEAVFAALGKHWDGLDIIVHSV 94 Query: 81 GILRMGATDQL--------SKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASD 132 G DQL ++E ++ ++ +F + + + R G+++T++ Sbjct: 95 GF---APGDQLDGDFTAVTTREGFRIAHDISAY-SFIALAKAGREMMKGRNGSLLTLSYL 150 Query: 133 AAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAE 192 A + G +KA+L++ + L G R N VS G RTL S Sbjct: 151 GAERTMPNYNVMGMAKASLEAGVRYLAGSLGAEGTRVNAVSAGPI-----RTLAASGIKS 205 Query: 193 EQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDGG 243 +++ E+ PL + +E+ N FL SDLAS I+ + + VDGG Sbjct: 206 FRKMLAANER---QTPLRRNVTIEEVGNAGAFLCSDLASGISGEILYVDGG 253 >2QHX-A nrPDB Length = 328 Score = 47.8 bits (112), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 38/132 (28%), Positives = 62/132 (46%), Gaps = 19/132 (14%) Query: 120 RQRGG--AIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGST 177 + RG +I+ + + P +G + Y +K AL+ L S LELA +R N V PG + Sbjct: 208 KHRGTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLS 267 Query: 178 DT--DMQRTLWVSDDAEEQRIRGFGEQFKLGIPL-GKIARPQEIANTILFLASDLASHIT 234 DM +W E + +PL + + E+++ ++FL S A +IT Sbjct: 268 VLVDDMPPAVW--------------EGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYIT 313 Query: 235 LQDIVVDGGSTL 246 + VDGG +L Sbjct: 314 GTCVKVDGGYSL 325 >3GRK-A nrPDB Length = 293 Score = 47.4 bits (111), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 61/240 (25%), Positives = 103/240 (42%), Gaps = 37/240 (15%) Query: 15 KGIGYATALAFVEAGAKVTGFDQ--AFTQEQYPFATEV-------MDVADAAQVAQVCQR 65 + I + A A EAGA++ Q A + P A E+ DVADAA + V + Sbjct: 43 RSIAWGIAKAAREAGAELAFTYQGDALKKRVEPLAEELGAFVAGHCDVADAASIDAVFET 102 Query: 66 LLAETERLDALVNAAGILRMGATDQL-------SKEDWQQTFAVNVGGAFNLFQQTMNQF 118 L + +LD LV+A G D+L S+ ++ T ++V + T Sbjct: 103 LEKKWGKLDFLVHAIG---FSDKDELTGRYIDTSEANFTNTMLISV------YSLTAVSR 153 Query: 119 RRQR----GGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSP 174 R ++ GG+I+T+ A + G +KAAL++ + ++L +R N +S Sbjct: 154 RAEKLMADGGSILTLTYYGAEKVMPNYNVMGVAKAALEASVKYLAVDLGPQNIRVNAISA 213 Query: 175 GSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHIT 234 G +TL S + + I + E PL + E+ + L+ SDL+ +T Sbjct: 214 GPI-----KTLAASGIGDFRYILKWNE---YNAPLRRTVTIDEVGDVGLYFLSDLSRSVT 265 >1MG5-A nrPDB Length = 255 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 40/170 (23%), Positives = 70/170 (41%), Gaps = 15/170 (8%) Query: 28 AGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGA 87 A A++ + T YP+ V A+ ++ + + A+ + +D L+N AGIL Sbjct: 45 AIAELKAINPKVTVTFYPYDVTV----PIAETTKLLKTIFAQLKTVDVLINGAGIL---- 96 Query: 88 TDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGA---IVTVASDAAHTPRIGMSAY 144 ++T AVN G N ++ + +++GG I + S + Y Sbjct: 97 ----DDHQIERTIAVNYTGLVNTTTAILDFWDKRKGGPGGIICNIGSVTGFNAIYQVPVY 152 Query: 145 GASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQ 194 +KAA+ + S+ +GV V+PG T T + D E Q Sbjct: 153 SGTKAAVVNFTSSLAKLAPITGVTAYTVNPGITRTTLVHKFNSWLDVEPQ 202 >1B15-A nrPDB Length = 254 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 47/201 (23%), Positives = 80/201 (39%), Gaps = 25/201 (12%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAK-------------VTGFDQAFTQEQYPFA 47 MD + KNV A GIG T+ V+ K + + F Sbjct: 1 MDLTNKNVIFVAALGGIGLDTSRELVKRNLKNFVILDRVENPTALAELKAINPKVNITFH 60 Query: 48 TEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGA 107 T + V A+ ++ +++ + + +D L+N AGIL ++T A+N G Sbjct: 61 TYDVTVP-VAESKKLLKKIFDQLKTVDILINGAGIL--------DDHQIERTIAINFTGL 111 Query: 108 FNLFQQTMNQFRRQRGGA---IVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAG 164 N ++ + +++GG I + S + Y ASKAA+ S S+ Sbjct: 112 VNTTTAILDFWDKRKGGPGGIIANICSVTGFNAIHQVPVYSASKAAVVSFTNSLAKLAPI 171 Query: 165 SGVRCNVVSPGSTDTDMQRTL 185 +GV ++PG T T + T Sbjct: 172 TGVTAYSINPGITRTPLVHTF 192 >2P91-A nrPDB Length = 285 Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 65/268 (24%), Positives = 105/268 (39%), Gaps = 42/268 (15%) Query: 3 FSGKNVWVTGAG--KGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADA--AQ 58 GK +TG + I Y A +F GA++ AFT V ++A + Sbjct: 19 LEGKRALITGVANERSIAYGIAKSFHREGAQL-----AFTYATPKLEKRVREIAKGFGSD 73 Query: 59 VAQVCQRLLAETER------------LDALVNAAGI-----LRMGATDQLSKEDWQQTFA 101 + C L E + LD +V++ + G D S+E ++ Sbjct: 74 LVVKCDVSLDEDIKNLKKFLEENWGSLDIIVHSIAYAPKEEFKGGVIDT-SREGFKIAMD 132 Query: 102 VNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLE 161 ++V L ++ + R GAIVT++ A + G +KAAL+S + + Sbjct: 133 ISVYSLIALTRELL-PLMEGRNGAIVTLSYYGAEKVVPHYNVMGIAKAALESTVRYLAYD 191 Query: 162 LAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFG---EQFKLGIPLGKIARPQEI 218 +A G R N +S G T + I GF E P GK +++ Sbjct: 192 IAKHGHRINAISAGPVKTLAAYS-----------ITGFHLLMEHTTKVNPFGKPITIEDV 240 Query: 219 ANTILFLASDLASHITLQDIVVDGGSTL 246 +T +FL SD A IT + + VD G + Sbjct: 241 GDTAVFLCSDWARAITGEVVHVDNGYHI 268 >5KOI-A nrPDB Length = 293 Score = 45.1 bits (105), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 49/200 (24%), Positives = 91/200 (45%), Gaps = 15/200 (7%) Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGI-----LRMGATDQLSKEDWQQTFAVNVGG 106 DV D A V V + + + LD LV+A G L+ D ++E++ +T ++ Sbjct: 86 DVEDIATVDAVFEEIEKKWGGLDFLVHAIGFSDKTELKGRYADVTTRENFSRTMVISAY- 144 Query: 107 AFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSG 166 +F Q + + GG+I+T+ + + G +KAAL+++ + + G Sbjct: 145 SFTEVAQRAEKLMKD-GGSILTLTYGGSTRTIPNYNVMGVAKAALEAMVRYLAADYGPQG 203 Query: 167 VRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLA 226 +R N +S G RTL + + + I F Q + PL + ++ + ++L Sbjct: 204 IRVNAISAGPV-----RTLAGAGIGDARAI--FSYQ-RRNSPLRRTVDIDDVGKSAVYLL 255 Query: 227 SDLASHITLQDIVVDGGSTL 246 SDL+S +T + VD G + Sbjct: 256 SDLSSGVTGEIHFVDSGYNI 275 >5WQO-A nrPDB Length = 234 Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 57/193 (29%), Positives = 79/193 (40%), Gaps = 19/193 (9%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD---------QAFTQEQYPFATEVMDVA 54 S NV + GA +GIG A AF++ GA+V QA + V Sbjct: 5 SMHNVLIVGASRGIGLGLADAFLQRGAQVFAVARRPQGSPGLQALAERAGERLQAVTGDL 64 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATD--QLSKEDWQQTFAVNVGGAFNLFQ 112 + A+ +L E R+D L+ AGI D ++ E Q F N L + Sbjct: 65 NQHDCAERIGEMLGE-RRIDRLIVNAGIYGPQQQDVAEIDAEQTAQLFLTNAIAPLRLAR 123 Query: 113 QTMNQFRRQRGGAIVTVASDAAHTPRIGMSA----YGASKAALKSLALSVGLELAGSGVR 168 R RGG + ++S A +G+SA YGASKAAL SL S E Sbjct: 124 ALSG--RVSRGGVVAFMSSQMASLA-LGLSATMPLYGASKAALNSLVRSWEGEFEELPFS 180 Query: 169 CNVVSPGSTDTDM 181 ++ PG T+M Sbjct: 181 LLLLHPGWVRTEM 193 >6CGE-A nrPDB Length = 328 Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 39/137 (28%), Positives = 63/137 (45%), Gaps = 5/137 (3%) Query: 51 MDVADAAQVAQVCQRLLAETE-RLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 +DV D+ VA +R+ TE R+D LV AG+ +G + L ++ VNV G Sbjct: 65 LDVRDSKSVAAARERV---TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 + Q + +R+ G ++ S Y ASK AL+ L S+ + L GV Sbjct: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 Query: 170 NVVSPGSTDTD-MQRTL 185 +++ G T M++ L Sbjct: 182 SLIECGPVHTAFMEKVL 198 >1A27-A nrPDB Length = 289 Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 46/181 (25%), Positives = 79/181 (43%), Gaps = 11/181 (6%) Query: 51 MDVADAAQVAQVCQRLLAETE-RLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 +DV D+ VA +R+ TE R+D LV AG+ +G + L ++ VNV G Sbjct: 64 LDVRDSKSVAAARERV---TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 120 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 + Q + +R+ G ++ S Y ASK AL+ L S+ + L GV Sbjct: 121 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 180 Query: 170 NVVSPGSTDTD-MQRTLWVSDDA-EEQRIRGFGEQFKLGIPLGKIAR-----PQEIANTI 222 +++ G T M++ L ++ + I F ++ ++ R P+E+A Sbjct: 181 SLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVF 240 Query: 223 L 223 L Sbjct: 241 L 241 >2NTV-A nrPDB Length = 268 Score = 41.2 bits (95), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 69/268 (25%), Positives = 116/268 (43%), Gaps = 32/268 (11%) Query: 3 FSGKNVWVTG--AGKGIGYATALAFVEAGAKV--TGFDQAF----TQEQYPFATEV--MD 52 GK + V+G I + A EAGA++ TGFD+ ++ P + +D Sbjct: 4 LEGKRILVSGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLIQRIADRLPDKAPLIELD 63 Query: 53 VADAAQVAQVCQRLLAET---ERLDALVNAAGILR---MGATDQL---SKEDWQQTFAVN 103 V + +A + +R+ AE +LD +V++ G + MG T+Q ED + ++ Sbjct: 64 VQNEEHLATLAERVTAEIGEGNKLDGVVHSIGFMPQTGMG-TNQFFDAPYEDVSKGIHIS 122 Query: 104 VGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYG---ASKAALKSLALSVGL 160 +L + + GG+IV + D P M AY +K+AL+S+ V Sbjct: 123 TYSYASLAKALL--LIMNSGGSIVGMDFD----PTRAMPAYNWMTVAKSALESVNRFVAR 176 Query: 161 ELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEE--QRIRGFGEQFKLGIPLG-KIARPQE 217 E GVR N+V+ G T + EE +++ E + P+G + P Sbjct: 177 EAGKYGVRSNLVAAGPIRTLAMSAIVGGAFGEEAGAQMQLLEEGWDQRAPIGWNMKDPTP 236 Query: 218 IANTILFLASDLASHITLQDIVVDGGST 245 +A T+ L S+ T I DGG++ Sbjct: 237 VAKTVCALLSEWLPATTGSIIYADGGAS 264 >5CFZ-A nrPDB Length = 305 Score = 40.4 bits (93), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 57/262 (21%), Positives = 107/262 (40%), Gaps = 26/262 (9%) Query: 3 FSGKNVWVTGAGK--GIGYATA---------LAFVEAGAKVTGFDQAFTQEQYPFATEVM 51 SGK + VTG I Y A LAF K+ G + F + Sbjct: 47 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 106 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGI-----LRMGATDQLSKEDWQQTFAVNVGG 106 DVA+ A + + L + D V++ G L + +++E ++ ++ Sbjct: 107 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 166 Query: 107 AFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSG 166 + + + G A++T++ A + G +KA+L++ + + G Sbjct: 167 FVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 224 Query: 167 VRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLA 226 VR N +S G RTL S + +++ E P+ + +++ N+ FL Sbjct: 225 VRVNAISAGPI-----RTLAASGIKDFRKMLAHCEAV---TPIRRTVTIEDVGNSAAFLC 276 Query: 227 SDLASHITLQDIVVDGGSTLGA 248 SDL++ I+ + + VDGG ++ A Sbjct: 277 SDLSAGISGEVVHVDGGFSIAA 298 >4JQC-A nrPDB Length = 282 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 57/262 (21%), Positives = 107/262 (40%), Gaps = 26/262 (9%) Query: 3 FSGKNVWVTGAGK--GIGYATA---------LAFVEAGAKVTGFDQAFTQEQYPFATEVM 51 SGK + VTG I Y A LAF K+ G + F + Sbjct: 24 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 83 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGI-----LRMGATDQLSKEDWQQTFAVNVGG 106 DVA+ A + + L + D V++ G L + +++E ++ ++ Sbjct: 84 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 143 Query: 107 AFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSG 166 + + + G A++T++ A + G +KA+L++ + + G Sbjct: 144 FVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 201 Query: 167 VRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLA 226 VR N +S G RTL S + +++ E P+ + +++ N+ FL Sbjct: 202 VRVNAISAGPI-----RTLAASGIKDFRKMLAHCEAVT---PIRRTVTIEDVGNSAAFLC 253 Query: 227 SDLASHITLQDIVVDGGSTLGA 248 SDL++ I+ + + VDGG ++ A Sbjct: 254 SDLSAGISGEVVHVDGGFSIAA 275 >5YCX-A nrPDB Length = 266 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 33/121 (27%), Positives = 55/121 (45%), Gaps = 8/121 (6%) Query: 123 GGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQ 182 GG I+T+ + G +KA+L++ + +L G+R N +S G Sbjct: 141 GGNILTLTYLGGERVVKNYNVMGVAKASLEASVKYLANDLGQHGIRVNAISAGPI----- 195 Query: 183 RTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDG 242 RTL + I + + PL + +E+ +T +FL SDLA +T ++I VD Sbjct: 196 RTLSAKGVGDFNSIL---REIEERAPLRRTTTQEEVGDTAVFLFSDLARGVTGENIHVDS 252 Query: 243 G 243 G Sbjct: 253 G 253 >3OIG-A nrPDB Length = 266 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 16/125 (12%) Query: 123 GGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQ 182 GG+IVT+ + G +KA+L + + +L +R N +S G T Sbjct: 140 GGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSA 199 Query: 183 RTLW----VSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDI 238 + + + D EE+ PL + P+E+ +T FL SD++ IT +++ Sbjct: 200 KGISDFNSILKDIEERA------------PLRRTTTPEEVGDTAAFLFSDMSRGITGENL 247 Query: 239 VVDGG 243 VD G Sbjct: 248 HVDSG 252 >4HBG-A nrPDB Length = 286 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 37/142 (26%), Positives = 58/142 (40%), Gaps = 16/142 (11%) Query: 73 LDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL----FQQTMNQFRR------QR 122 ++ L+N AG+ + + + + Q VN + + M RR Q Sbjct: 114 VNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQS 173 Query: 123 GGAIVTVASDAAHTPRI---GMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTD- 178 + S H+ ++ G S Y ASKAAL + E+ +RC +SPG Sbjct: 174 ARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKG 233 Query: 179 TDMQRTLWVSDDAEEQRIRGFG 200 TDM + L V +A+E R G Sbjct: 234 TDMIQNLPV--EAKEMLERTIG 253 >4ZJU-A nrPDB Length = 275 Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust. Identities = 33/122 (27%), Positives = 54/122 (44%), Gaps = 8/122 (6%) Query: 122 RGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDM 181 R G ++T+ + + G +KA+L++ + L G+R N +S G Sbjct: 148 RQGCLLTLTYQGSERVMPNYNVMGMAKASLEAGVRYLASSLGVDGIRVNAISAGPI---- 203 Query: 182 QRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVD 241 RTL S +++ E+ PL + +E+ N LFL S AS IT + + VD Sbjct: 204 -RTLAASGIKSFRKMLDANEKVA---PLKRNVTIEEVGNAALFLCSPWASGITGEILYVD 259 Query: 242 GG 243 G Sbjct: 260 AG 261 >3K2E-A nrPDB Length = 296 Score = 36.2 bits (82), Expect = 0.014, Method: Compositional matrix adjust. Identities = 56/240 (23%), Positives = 93/240 (38%), Gaps = 19/240 (7%) Query: 15 KGIGYATALAFVEAGAKV--TGFDQAFTQEQYPFA-------TEVMDVADAAQVAQVCQR 65 K + + A A GA+V T + F + P A T DV+DA V + + Sbjct: 42 KSLAWGIAKAVCAQGAEVALTYLSETFKKRVDPLAESLGVKLTVPCDVSDAESVDNMFKV 101 Query: 66 LLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFR--RQRG 123 L E LD +V+A + F ++ + F ++ G Sbjct: 102 LAEEWGSLDFVVHAVAFSDKNELKGRYVDTSLGNFLTSMHISCYSFTYIASKAEPLMTNG 161 Query: 124 GAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQR 183 G+I+T++ A + G KAAL++ + ++L +R N +S G R Sbjct: 162 GSILTLSYYGAEKVVPHYNVMGVCKAALEASVKYLAVDLGKQQIRVNAISAGPV-----R 216 Query: 184 TLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDGG 243 TL S ++ I + K PL + ++ L+L SDL T + + VD G Sbjct: 217 TLASSGISDFHYILTWN---KYNSPLRRNTTLDDVGGAALYLLSDLGRGTTGETVHVDCG 273 >5TQV-A nrPDB Length = 233 Score = 36.2 bits (82), Expect = 0.014, Method: Compositional matrix adjust. Identities = 45/184 (24%), Positives = 71/184 (38%), Gaps = 12/184 (6%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKV--TGFDQAFTQEQYPFATEV--MDVADAAQVAQ 61 K V + GA +G+G + G V T D A +D+ Q+A Sbjct: 10 KTVLIVGASRGLGREFVRQYQRDGWNVIATARDDASLAALRALGAHAHALDITQPEQIAA 69 Query: 62 VCQRLLAETERLDALVNAAGIL--RMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFR 119 + +L + ERLD V +G+ R + ++ +D+ NV G L + Sbjct: 70 LGWKL--DGERLDVAVVVSGVYGPRTEGVETIASDDFDTVMHTNVRGPMQLLPILLPLVE 127 Query: 120 RQRGGAIVTVASDAAHTPRIGMSA--YGASKAALKSLALSVGLELAGSGVRCNVVSPGST 177 RG V + + + G + Y ASKAAL + L+ + C + PG Sbjct: 128 DARGVLAVVSSRMGSISEATGTTGWLYRASKAALNDVLRIASLQTRHAA--CISLHPGWV 185 Query: 178 DTDM 181 TDM Sbjct: 186 RTDM 189 >4ALL-A nrPDB Length = 277 Score = 35.4 bits (80), Expect = 0.025, Method: Compositional matrix adjust. Identities = 33/124 (26%), Positives = 55/124 (44%), Gaps = 14/124 (11%) Query: 123 GGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQ 182 GG+IV + G +KA+L++ + L+L +R N +S G Sbjct: 160 GGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPI----- 214 Query: 183 RTLWVSDDAEEQRIRGFG---EQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIV 239 RTL + + GF ++ + PL + E+ T +L SDL+S +T ++I Sbjct: 215 RTLSA------KGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIH 268 Query: 240 VDGG 243 VD G Sbjct: 269 VDSG 272 >4Z3K-A nrPDB Length = 275 Score = 33.5 bits (75), Expect = 0.076, Method: Compositional matrix adjust. Identities = 38/125 (30%), Positives = 50/125 (40%), Gaps = 15/125 (12%) Query: 64 QRLLAETERLDALVNAAGIL---RMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRR 120 QRLL L+N AG L G D +A+N+ L + F Sbjct: 107 QRLL--------LINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPD 158 Query: 121 QRG--GAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTD 178 G +V ++S A P G + Y A KAA L + LE VR +PG D Sbjct: 159 SPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE--EPNVRVLNYAPGPLD 216 Query: 179 TDMQR 183 TDMQ+ Sbjct: 217 TDMQQ 221 >4HWK-A nrPDB Length = 288 Score = 33.5 bits (75), Expect = 0.082, Method: Compositional matrix adjust. Identities = 38/125 (30%), Positives = 50/125 (40%), Gaps = 15/125 (12%) Query: 64 QRLLAETERLDALVNAAGIL---RMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRR 120 QRLL L+N AG L G D +A+N+ L + F Sbjct: 120 QRLL--------LINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPD 171 Query: 121 QRG--GAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTD 178 G +V ++S A P G + Y A KAA L + LE VR +PG D Sbjct: 172 SPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE--EPNVRVLNYAPGPLD 229 Query: 179 TDMQR 183 TDMQ+ Sbjct: 230 TDMQQ 234 >5JY1-A nrPDB Length = 274 Score = 33.5 bits (75), Expect = 0.096, Method: Compositional matrix adjust. Identities = 58/243 (23%), Positives = 92/243 (37%), Gaps = 36/243 (14%) Query: 24 AFVEAGAKV--------TGFDQAFTQEQYPFATEVM----DVADAAQVAQVCQRLLAETE 71 +F GA V TG + QE + DV A + + + + Sbjct: 33 SFGNEGAAVIIAEINESTG--RQVEQEIREMGGRSLFVKTDVTSKASIEAAVRSAVEQFG 90 Query: 72 RLDALVNAA-----GILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAI 126 LD LVN A +L TD++ +QT ++ + + R +R G I Sbjct: 91 SLDILVNNAFVPTPNVLLEEKTDEML----EQTLTTSLWATWWAMRAAFVPMRERRWGRI 146 Query: 127 VTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQRTLW 186 V S T Y +KA + L S E + N ++P T M T + Sbjct: 147 VNFYSIDTETGAWLHGDYNTAKAGIVGLTRSAASEWGRFNITVNAIAP----TAMGATFF 202 Query: 187 --VSDDAEEQRIRGFGEQFKLGIPLGKIARP-QEIANTILFLASDLASHITLQDIVVDGG 243 + + E F E+ PLG+ P Q+I +F AS+++ +T + + VDGG Sbjct: 203 ELAAKNPE------FAERSAAARPLGRSGDPEQDIGPAAVFFASEMSRFVTGETLHVDGG 256 Query: 244 STL 246 L Sbjct: 257 LHL 259 >5BP9-A nrPDB Length = 281 Score = 32.3 bits (72), Expect = 0.21, Method: Compositional matrix adjust. Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 12/76 (15%) Query: 11 TGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMD---VADAAQVAQVCQRLL 67 GAG G ALA E+G +V+ D + P + EVM V DA QV +R Sbjct: 108 VGAGSG---CHALALQESGKEVSAIDIS------PLSVEVMKLRGVKDARQVNLFDERFA 158 Query: 68 AETERLDALVNAAGIL 83 A + + L+N +GI+ Sbjct: 159 ATFDTILMLMNGSGII 174 >3SC6-A nrPDB Length = 287 Score = 32.0 bits (71), Expect = 0.27, Method: Compositional matrix adjust. Identities = 30/119 (25%), Positives = 53/119 (44%), Gaps = 27/119 (22%) Query: 44 YPFATEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVN 103 YPF +++D+ + +QV QV Q + R +++ A ++ DQ KE + +N Sbjct: 33 YPFDKKLLDITNISQVQQVVQEI-----RPHIIIHCAAYTKV---DQAEKER-DLAYVIN 83 Query: 104 VGGAFNLFQQTMNQFRRQRGGAIVTVASDAA------------HTPRIGMSAYGASKAA 150 GA N+ + + G +V +++D H P ++ YGASK A Sbjct: 84 AIGARNVAVAS-----QLVGAKLVYISTDYVFQGDRPEGYDEFHNPA-PINIYGASKYA 136 >3ORF-A nrPDB Length = 251 Score = 32.0 bits (71), Expect = 0.27, Method: Compositional matrix adjust. Identities = 45/187 (24%), Positives = 77/187 (41%), Gaps = 19/187 (10%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQ--VAQVC 63 KN+ V G +G F D + P A + D+ + + V Sbjct: 23 KNILVLGGSGALGAEVVKFFKSKSWNTISIDF----RENPNADHSFTIKDSGEEEIKSVI 78 Query: 64 QRLLAETERLDALVNAAGILRMG--ATDQLSKEDWQQTFAVNVGGAF---NLFQQTMNQF 118 +++ +++ ++D V AAG G ++D+ K + +N+ AF ++ + +NQ Sbjct: 79 EKINSKSIKVDTFVCAAGGWSGGNASSDEFLKSV-KGMIDMNLYSAFASAHIGAKLLNQ- 136 Query: 119 RRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAG--SGVRCNVVSPGS 176 GG V + AA GM AYGA+KAA + + E G +G + P + Sbjct: 137 ----GGLFVLTGASAALNRTSGMIAYGATKAATHHIIKDLASENGGLPAGSTSLGILPVT 192 Query: 177 TDTDMQR 183 DT R Sbjct: 193 LDTPTNR 199 >5PGZ-A nrPDB Length = 276 Score = 32.0 bits (71), Expect = 0.29, Method: Compositional matrix adjust. Identities = 50/191 (26%), Positives = 73/191 (38%), Gaps = 38/191 (19%) Query: 5 GKNVWVTGAGKGIGYATALAFVEAGAKV--TGFDQAFTQEQYPFATEVMDVADAAQVAQV 62 GK V VTGA KGIG A + GA V T + Q+ E + A A +A Sbjct: 18 GKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLE-LGAASAHYIAGT 76 Query: 63 CQRL-LAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRR- 120 + + AE + AG L MG D L QT + +LF ++ RR Sbjct: 77 MEDMTFAE-----QFIVKAGKL-MGGLDMLILNHITQT-------SLSLFHDDIHSVRRV 123 Query: 121 --------------------QRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGL 160 Q G+I ++S A + ++ Y ASK AL ++ Sbjct: 124 MEVNFLSYVVMSTAALPMLKQSNGSIAVISSLAGKMTQPMIAPYSASKFALDGFFSTIRT 183 Query: 161 ELAGSGVRCNV 171 EL + V ++ Sbjct: 184 ELYITKVNVSI 194 >1SNY-A nrPDB Length = 267 Score = 31.6 bits (70), Expect = 0.32, Method: Compositional matrix adjust. Identities = 16/42 (38%), Positives = 23/42 (54%) Query: 140 GMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDM 181 GM AY SK+AL + S+ ++L + C + PG TDM Sbjct: 185 GMYAYRTSKSALNAATKSLSVDLYPQRIMCVSLHPGWVKTDM 226 >3N0T-A nrPDB Length = 469 Score = 31.2 bits (69), Expect = 0.47, Method: Compositional matrix adjust. Identities = 14/40 (35%), Positives = 22/40 (55%) Query: 44 YPFATEVMDVADAAQVAQVCQRLLAETERLDALVNAAGIL 83 YP+ T+ + A V C RLL+E +R+ L AG++ Sbjct: 251 YPYPTDFLGPLPANPVKVGCDRLLSEAQRITGLRALAGLV 290 >5LCX-A nrPDB Length = 316 Score = 30.8 bits (68), Expect = 0.58, Method: Compositional matrix adjust. Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 14/87 (16%) Query: 10 VTGAGKGIGYATALAFVEAGAKVT--------GFD--QAFTQE----QYPFATEVMDVAD 55 VTGA KGIG+ E G V G + Q +E + +DV D Sbjct: 12 VTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKELNVSENRLVFHQLDVTD 71 Query: 56 AAQVAQVCQRLLAETERLDALVNAAGI 82 A VA V + ++ +LD LVN AG+ Sbjct: 72 LASVAAVAVFIKSKFGKLDILVNNAGV 98 >2YQ5-A nrPDB Length = 343 Score = 30.4 bits (67), Expect = 0.84, Method: Compositional matrix adjust. Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 2/59 (3%) Query: 17 IGYATALAFVEAGAKVTGFDQAFTQEQYPF--ATEVMDVADAAQVAQVCQRLLAETERL 73 IG A A F GAKV +D A+ E PF T+ V A + + L TE + Sbjct: 159 IGSAVAEIFSAMGAKVIAYDVAYNPEFEPFLTYTDFDTVLKEADIVSLHTPLFPSTENM 217 >4OYR-A nrPDB Length = 289 Score = 30.0 bits (66), Expect = 0.96, Method: Compositional matrix adjust. Identities = 41/130 (31%), Positives = 57/130 (43%), Gaps = 14/130 (10%) Query: 123 GGAIVTVASDAAHTPRIGMSAYG---ASKAALKSLALSVGLELAGSGVRCNVVSPGSTDT 179 GG+IV + D P M AY +K+AL+S+ V E GVR N+V+ G T Sbjct: 161 GGSIVGMDFD----PSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRT 216 Query: 180 DMQRTLWVSDDAEE--QRIRGFGEQFKLGIPLG---KIARPQEIANTILFLASDLASHIT 234 + EE +I+ E + P+G K A P +A T+ L SD T Sbjct: 217 LAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATP--VAKTVCALLSDWLPATT 274 Query: 235 LQDIVVDGGS 244 I DGG+ Sbjct: 275 GDIIYADGGA 284 >1ENP-A nrPDB Length = 312 Score = 30.0 bits (66), Expect = 0.96, Method: Compositional matrix adjust. Identities = 41/141 (29%), Positives = 57/141 (40%), Gaps = 27/141 (19%) Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYG----ASKAALKS----LALSVGLEL 162 F MN GGA +++ A+ RI + YG ++KAAL+S LA G + Sbjct: 173 FLPIMNP-----GGASISLTYIASE--RI-IPGYGGGMSSAKAALESDTRVLAFEAGRK- 223 Query: 163 AGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTI 222 +R N +S G + + + D E P+ K E+ N Sbjct: 224 --QNIRVNTISAGPLGSRAAKAIGFIDTMIEYSYNN--------APIQKTLTADEVGNAA 273 Query: 223 LFLASDLASHITLQDIVVDGG 243 FL S LAS IT I VD G Sbjct: 274 AFLVSPLASAITGATIYVDNG 294 >2Q1W-A nrPDB Length = 333 Score = 29.6 bits (65), Expect = 1.2, Method: Compositional matrix adjust. Identities = 33/113 (29%), Positives = 46/113 (40%), Gaps = 18/113 (15%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQ-----YPFATEVM-DVADAAQV 59 K V++TG IG A +E G KV G D T + +P T V +AD A V Sbjct: 22 KKVFITGICGQIGSHIAELLLERGDKVVGIDNFATGRREHLKDHPNLTFVEGSIADHALV 81 Query: 60 AQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQ 112 Q+ L + DA+V+ A + +DW N G N+ Q Sbjct: 82 NQLIGDL-----QPDAVVHTAASYK-------DPDDWYNDTLTNCVGGSNVVQ 122 >5L51-A nrPDB Length = 324 Score = 28.9 bits (63), Expect = 2.3, Method: Compositional matrix adjust. Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 2/41 (4%) Query: 141 MSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDM 181 SAY SKAAL + + + R N V PG T TD+ Sbjct: 243 FSAYKVSKAALNAYTRIIAKKY--PSFRINAVCPGYTKTDL 281 >3IAU-A nrPDB Length = 366 Score = 28.5 bits (62), Expect = 2.5, Method: Compositional matrix adjust. Identities = 15/52 (28%), Positives = 25/52 (48%), Gaps = 4/52 (7%) Query: 84 RMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAH 135 R+G + +ED Q+ F+ + GA+N+ M+ R+ V AS H Sbjct: 72 RLGVNFYIKREDKQRVFSFKLRGAYNM----MSNLSREELDKGVITASAGNH 119 >3OTH-A nrPDB Length = 412 Score = 28.5 bits (62), Expect = 2.7, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 18/72 (25%) Query: 141 MSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFG 200 +S YGA AALK AG C+ V + D D+ R++ E+ +RG Sbjct: 138 ISNYGAGLAALK----------AGIPTICHGVGRDTPD-DLTRSI-------EEEVRGLA 179 Query: 201 EQFKLGIPLGKI 212 ++ L +P G+I Sbjct: 180 QRLGLDLPPGRI 191 >3DWF-A nrPDB Length = 276 Score = 28.5 bits (62), Expect = 2.9, Method: Compositional matrix adjust. Identities = 15/29 (51%), Positives = 16/29 (55%) Query: 5 GKNVWVTGAGKGIGYATALAFVEAGAKVT 33 GK V VTGA KGIG A + GA V Sbjct: 11 GKKVIVTGASKGIGREIAYHLAKMGAHVV 39 >4ZZV-A nrPDB Length = 438 Score = 27.7 bits (60), Expect = 4.3, Method: Compositional matrix adjust. Identities = 16/59 (27%), Positives = 26/59 (44%), Gaps = 5/59 (8%) Query: 157 SVGLELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKL-----GIPLG 210 + G+ +G+ +R N V+ GS RT + DD Q ++F G+P G Sbjct: 81 TYGITASGNSLRLNFVTNGSQKNVGSRTYLMKDDTHYQTFNLLNQEFTFDVDVSGLPCG 139 >1N5D-A nrPDB Length = 288 Score = 27.7 bits (60), Expect = 4.6, Method: Compositional matrix adjust. Identities = 38/133 (28%), Positives = 50/133 (37%), Gaps = 13/133 (9%) Query: 10 VTGAGKGIGYATALAFVE--AGAKV-TGFDQAFTQ--------EQYPFATEVMDVADAAQ 58 VTGA KGIG+A AG V T D A Q E +D+ D Sbjct: 9 VTGANKGIGFAIVRDLCRQFAGDVVLTARDVARGQAAVKQLQAEGLSPRFHQLDIIDLQS 68 Query: 59 VAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQF 118 + +C L E LD LVN A I + T N G N+ + + Sbjct: 69 IRALCDFLRKEYGGLDVLVNNAAIAFQLDNPTPFHIQAELTMKTNFMGTRNVCTELLPLI 128 Query: 119 RRQRGGAIVTVAS 131 + Q G +V V+S Sbjct: 129 KPQ--GRVVNVSS 139 >1DIR-A nrPDB Length = 241 Score = 27.3 bits (59), Expect = 6.6, Method: Compositional matrix adjust. Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 2/65 (3%) Query: 121 QRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAG--SGVRCNVVSPGSTD 178 + GG + + AA GM YG +K A+ L S+ + +G SG V P + D Sbjct: 124 KEGGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKNSGMPSGAAAIAVLPVTLD 183 Query: 179 TDMQR 183 T M R Sbjct: 184 TPMNR 188 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2FWM-X nrPDB 287 4e-78 2PNF-A nrPDB 263 5e-71 2HQ1-A nrPDB 259 6e-70 3RSH-A nrPDB 259 8e-70 4JRO-A nrPDB 259 9e-70 3OSU-A nrPDB 258 2e-69 2UVD-A nrPDB 258 2e-69 2C07-A nrPDB 255 1e-68 3LYL-A nrPDB 253 5e-68 1Q7C-A nrPDB 252 1e-67 5ITV-A nrPDB 252 1e-67 5CDY-A nrPDB 250 3e-67 3FTP-A nrPDB 250 3e-67 4M8S-A nrPDB 249 7e-67 3EMK-A nrPDB 248 2e-66 2NM0-A nrPDB 246 8e-66 4NBT-A nrPDB 245 9e-66 3WOH-A nrPDB 245 2e-65 3F9I-A nrPDB 243 5e-65 4DMM-A nrPDB 240 5e-64 4BO1-A nrPDB 238 1e-63 2PH3-A nrPDB 238 2e-63 5OVL-A nrPDB 237 3e-63 3O4R-A nrPDB 237 5e-63 3GRP-A nrPDB 236 6e-63 3OEC-A nrPDB 235 1e-62 1AE1-A nrPDB 234 2e-62 3EZL-A nrPDB 233 4e-62 4IIN-A nrPDB 233 5e-62 4NBV-A nrPDB 233 6e-62 4KMS-A nrPDB 232 8e-62 5YSS-A nrPDB 232 1e-61 5OVJ-A nrPDB 232 1e-61 4K6F-A nrPDB 232 1e-61 4RZH-A nrPDB 230 4e-61 2EW8-A nrPDB 230 6e-61 1GEE-A nrPDB 229 8e-61 1UZM-A nrPDB 229 9e-61 6NRP-A nrPDB 228 1e-60 3AUT-A nrPDB 227 3e-60 2ZAT-A nrPDB 227 3e-60 2AE2-A nrPDB 227 3e-60 1GEG-A nrPDB 227 4e-60 5U9P-A nrPDB 226 4e-60 3VZS-A nrPDB 226 6e-60 5VT6-A nrPDB 225 1e-59 5OJG-A nrPDB 225 2e-59 2CDH-G nrPDB 224 3e-59 4Z9Y-A nrPDB 224 3e-59 1YXM-A nrPDB 224 3e-59 4RZI-B nrPDB 222 8e-59 2Q2Q-A nrPDB 222 1e-58 3V2H-A nrPDB 220 7e-58 1NFF-A nrPDB 219 8e-58 3W8F-A nrPDB 218 2e-57 6CI9-A nrPDB 218 2e-57 1X1T-A nrPDB 218 2e-57 4CQL-A nrPDB 216 5e-57 4CQM-B nrPDB 216 6e-57 1K2W-A nrPDB 216 6e-57 3UVE-A nrPDB 215 2e-56 3WTC-A nrPDB 213 5e-56 5T5Q-A nrPDB 213 5e-56 3WYE-A nrPDB 213 6e-56 1O5I-A nrPDB 212 1e-55 4IS3-A nrPDB 211 2e-55 3OIC-A nrPDB 209 8e-55 4DBZ-A nrPDB 209 9e-55 4MOW-A nrPDB 209 1e-54 3RWB-A nrPDB 208 1e-54 4E6P-A nrPDB 208 2e-54 4IIV-A nrPDB 208 2e-54 1AHH-A nrPDB 208 2e-54 3V2G-A nrPDB 207 3e-54 3T7C-A nrPDB 207 3e-54 3D3W-A nrPDB 206 7e-54 2CFC-A nrPDB 206 9e-54 1DOH-A nrPDB 205 1e-53 2HSD-A nrPDB 204 3e-53 3R3S-A nrPDB 204 3e-53 3A28-C nrPDB 204 4e-53 5EJ2-A nrPDB 203 7e-53 4AVY-A nrPDB 202 1e-52 3UN1-A nrPDB 202 1e-52 2AG5-A nrPDB 202 1e-52 1CYD-A nrPDB 202 1e-52 4HP8-A nrPDB 201 2e-52 4FC7-A nrPDB 201 2e-52 3UF0-A nrPDB 200 4e-52 3U5T-A nrPDB 200 6e-52 5B1Y-A nrPDB 198 1e-51 2B4Q-A nrPDB 197 4e-51 3U4C-A nrPDB 195 2e-50 5JS6-A nrPDB 194 4e-50 3V8B-A nrPDB 192 1e-49 1H5Q-A nrPDB 190 4e-49 3ZV3-A nrPDB 189 1e-48 4EGF-A nrPDB 189 1e-48 3GDF-A nrPDB 188 1e-48 2P91-A nrPDB 188 2e-48 1BDB-A nrPDB 187 4e-48 1HXH-A nrPDB 187 4e-48 4TRR-A nrPDB 186 8e-48 4RGB-A nrPDB 183 5e-47 2GDZ-A nrPDB 183 5e-47 4M89-A nrPDB 181 3e-46 5TF4-A nrPDB 179 1e-45 2BGM-A nrPDB 178 1e-45 5CFZ-A nrPDB 178 2e-45 5O3Z-A nrPDB 177 4e-45 4JQC-A nrPDB 176 9e-45 3PXX-A nrPDB 175 1e-44 2YW9-A nrPDB 175 2e-44 4GKB-A nrPDB 175 2e-44 4CR6-A nrPDB 175 2e-44 4NR0-A nrPDB 174 4e-44 3GRK-A nrPDB 173 6e-44 4J3F-A nrPDB 172 1e-43 5KOI-A nrPDB 171 3e-43 5I9N-A nrPDB 169 6e-43 2X9N-A nrPDB 169 7e-43 3OML-A nrPDB 169 8e-43 5IZ4-A nrPDB 169 1e-42 1W73-A nrPDB 169 1e-42 3OIG-A nrPDB 164 3e-41 4DA9-A nrPDB 163 8e-41 5YCX-A nrPDB 159 1e-39 1A27-A nrPDB 159 1e-39 2O23-A nrPDB 158 2e-39 6CGE-A nrPDB 157 3e-39 3RKU-A nrPDB 157 5e-39 2QHX-A nrPDB 154 4e-38 1E3W-A nrPDB 153 5e-38 2BFA-A nrPDB 153 6e-38 1P33-A nrPDB 153 6e-38 2NWQ-A nrPDB 152 2e-37 5ILO-A nrPDB 141 3e-34 4DRY-A nrPDB 139 1e-33 2DKN-A nrPDB 137 6e-33 3E9N-A nrPDB 136 1e-32 3KZV-A nrPDB 133 9e-32 2NTV-A nrPDB 131 3e-31 3U9L-A nrPDB 129 1e-30 1FJH-A nrPDB 129 1e-30 3PPI-A nrPDB 126 9e-30 1B15-A nrPDB 126 1e-29 1MG5-A nrPDB 116 8e-27 5WQO-A nrPDB 103 9e-23 Sequences not found previously or not previously below threshold: 4ZJU-A nrPDB 172 2e-43 5JY1-A nrPDB 168 3e-42 3K2E-A nrPDB 155 2e-38 4ALL-A nrPDB 152 1e-37 4NK4-A nrPDB 149 1e-36 2PD3-A nrPDB 141 3e-34 4OYR-A nrPDB 127 3e-30 4Q9N-A nrPDB 121 3e-28 2O2S-A nrPDB 121 4e-28 1ENP-A nrPDB 119 1e-27 4HBG-A nrPDB 116 1e-26 3UCF-A nrPDB 110 7e-25 2HRB-A nrPDB 109 2e-24 5PGZ-A nrPDB 107 4e-24 3DWF-A nrPDB 107 4e-24 5L51-A nrPDB 105 2e-23 2PTG-A nrPDB 104 4e-23 3F4B-A nrPDB 102 1e-22 1N5D-A nrPDB 101 3e-22 3BHI-A nrPDB 99 1e-21 1SNY-A nrPDB 99 2e-21 3O26-A nrPDB 95 2e-20 2O2Y-A nrPDB 93 1e-19 5LCX-A nrPDB 90 1e-18 5TQV-A nrPDB 85 2e-17 4Z3K-A nrPDB 79 1e-15 4HWK-A nrPDB 79 1e-15 1OAA-A nrPDB 77 6e-15 3ORF-A nrPDB 69 2e-12 3SLK-A nrPDB 64 5e-11 2PK3-A nrPDB 63 1e-10 1OOE-A nrPDB 62 2e-10 1DIR-A nrPDB 61 6e-10 3RFT-A nrPDB 57 7e-09 4LIS-A nrPDB 56 1e-08 1VL0-A nrPDB 52 2e-07 2Q1W-A nrPDB 51 7e-07 3SC6-A nrPDB 49 2e-06 1UDA-A nrPDB 46 1e-05 1Z45-A nrPDB 46 2e-05 2NNL-D nrPDB 45 3e-05 6BWL-A nrPDB 45 4e-05 1RKX-A nrPDB 44 4e-05 4G5H-A nrPDB 44 6e-05 2GN9-A nrPDB 44 6e-05 1WVG-A nrPDB 42 2e-04 1I3M-A nrPDB 42 3e-04 1BXK-A nrPDB 42 3e-04 1ZZE-A nrPDB 41 5e-04 3SXP-A nrPDB 41 7e-04 5INT-A nrPDB 41 7e-04 3ENK-A nrPDB 40 0.001 1GY8-A nrPDB 39 0.001 4KTT-E nrPDB 38 0.003 2PZM-A nrPDB 38 0.005 4KDR-A nrPDB 37 0.005 4KDC-A nrPDB 37 0.006 1KEU-A nrPDB 37 0.006 6DEB-A nrPDB 37 0.008 3WMX-A nrPDB 37 0.009 5B6K-A nrPDB 37 0.010 4EJ0-A nrPDB 36 0.011 4J2O-A nrPDB 36 0.016 2Z95-A nrPDB 36 0.016 3BIC-A nrPDB 36 0.018 2HUN-A nrPDB 36 0.020 4WPG-A nrPDB 36 0.022 5K1S-A nrPDB 35 0.026 5F5N-A nrPDB 35 0.026 1OC2-A nrPDB 35 0.028 3OND-A nrPDB 35 0.032 3DMF-A nrPDB 35 0.034 2C20-A nrPDB 35 0.039 5LV5-A nrPDB 34 0.054 4J6F-A nrPDB 34 0.054 2GGS-A nrPDB 34 0.058 3DFZ-A nrPDB 34 0.061 3R0Q-C nrPDB 34 0.074 1R66-A nrPDB 34 0.076 3N58-A nrPDB 34 0.084 4BKP-A nrPDB 34 0.085 6GCS-E nrPDB 33 0.14 4EUF-A nrPDB 33 0.14 2DFV-A nrPDB 33 0.15 4R1U-A nrPDB 32 0.16 4K28-A nrPDB 32 0.16 7REQ-A nrPDB 32 0.17 6ACF-A nrPDB 32 0.18 2C54-A nrPDB 32 0.19 5YWN-A nrPDB 32 0.24 2YQ5-A nrPDB 32 0.28 6BI4-A nrPDB 32 0.31 6GBN-A nrPDB 31 0.35 5EGS-A nrPDB 31 0.37 1EQ2-A nrPDB 31 0.39 2GAS-A nrPDB 31 0.41 4EJ6-A nrPDB 31 0.46 5ENV-A nrPDB 31 0.49 1RPN-A nrPDB 31 0.50 5N2I-A nrPDB 31 0.53 5A3V-A nrPDB 31 0.55 5I1W-A nrPDB 31 0.56 3X2F-A nrPDB 31 0.58 3NJ4-A nrPDB 31 0.59 1O89-A nrPDB 31 0.59 5TC4-A nrPDB 31 0.68 2X86-A nrPDB 31 0.71 4PVC-A nrPDB 31 0.72 2OWO-A nrPDB 31 0.72 5ZZ6-A nrPDB 30 0.81 4A10-A nrPDB 30 0.83 3H9U-A nrPDB 30 0.92 1DB3-A nrPDB 30 0.94 1LU9-A nrPDB 30 1.2 2VN8-A nrPDB 30 1.3 2Q4B-A nrPDB 29 1.3 1IE3-A nrPDB 29 1.4 4N18-A nrPDB 29 1.5 2HK7-A nrPDB 29 1.5 1YXY-A nrPDB 29 1.5 2ZJ1-A nrPDB 29 1.6 3K8Z-A nrPDB 29 1.7 5ZZM-A nrPDB 29 1.7 3JTM-A nrPDB 29 1.7 2A9F-A nrPDB 29 1.7 1XDW-A nrPDB 29 2.1 3VPX-A nrPDB 29 2.3 6ACQ-A nrPDB 29 2.4 4UUM-A nrPDB 29 2.5 2ZSK-A nrPDB 29 2.5 1NHQ-A nrPDB 29 2.5 3R9I-A nrPDB 29 2.6 5ER0-A nrPDB 29 2.7 4WOK-A nrPDB 29 2.7 1ZDL-A nrPDB 29 2.8 1MLD-A nrPDB 28 3.0 1C0L-A nrPDB 28 3.1 4K22-A nrPDB 28 3.1 4E0B-A nrPDB 28 3.2 3ZXS-A nrPDB 28 3.2 4WLE-A nrPDB 28 3.3 6C55-A nrPDB 28 3.6 4UUP-A nrPDB 28 3.8 1EDZ-A nrPDB 28 3.9 3NE8-A nrPDB 28 3.9 4A26-A nrPDB 28 4.1 5NHS-A nrPDB 28 4.2 3HG7-A nrPDB 28 4.3 4PRK-A nrPDB 28 4.5 5GXF-A nrPDB 28 4.8 1YB5-A nrPDB 28 4.8 4OH1-A nrPDB 28 5.0 6F4U-A nrPDB 27 5.1 6F02-A nrPDB 27 5.1 6BII-A nrPDB 27 5.2 4LWO-B nrPDB 27 5.2 2HES-X nrPDB 27 5.2 3K92-A nrPDB 27 5.4 4A5O-A nrPDB 27 5.4 1NP3-A nrPDB 27 5.9 3GFB-A nrPDB 27 6.3 2CWD-A nrPDB 27 6.4 5UZH-A nrPDB 27 6.8 2BC1-A nrPDB 27 6.8 4B4V-A nrPDB 27 7.7 3LED-A nrPDB 27 7.9 6APE-A nrPDB 27 7.9 5IS8-A nrPDB 27 8.1 4IKP-A nrPDB 27 8.1 3B3J-A nrPDB 27 8.1 3R7T-A nrPDB 27 8.5 2EXX-A nrPDB 27 8.5 1HE4-A nrPDB 27 8.6 6GNF-A nrPDB 27 8.7 2X3N-A nrPDB 27 8.7 3DQQ-A nrPDB 27 8.9 3IP1-A nrPDB 27 9.7 >2FWM-X nrPDB Length = 250 Score = 287 bits (734), Expect = 4e-78, Method: Composition-based stats. Identities = 248/248 (100%), Positives = 248/248 (100%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVA 60 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVA Sbjct: 3 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVA 62 Query: 61 QVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRR 120 QVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRR Sbjct: 63 QVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRR 122 Query: 121 QRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTD 180 QRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTD Sbjct: 123 QRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTD 182 Query: 181 MQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVV 240 MQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVV Sbjct: 183 MQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVV 242 Query: 241 DGGSTLGA 248 DGGSTLGA Sbjct: 243 DGGSTLGA 250 >2PNF-A nrPDB Length = 248 Score = 263 bits (673), Expect = 5e-71, Method: Composition-based stats. Identities = 77/255 (30%), Positives = 120/255 (47%), Gaps = 21/255 (8%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQY-----------PFATE 49 + GK VTG+ +GIG A A AG+ V + + + Sbjct: 3 IKLQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGV 62 Query: 50 VMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 M++ + + + + + +D LVN AGI R ++S DW++ VN+ G F Sbjct: 63 EMNLLSEESINKAFEEIYNLVDGIDILVNNAGITRDKLFLRMSLLDWEEVLKVNLTGTFL 122 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 + Q ++ + +QR G IV ++S T +G Y +KA L S+ ELA V Sbjct: 123 VTQNSLRKMIKQRWGRIVNISSVVGFTGNVGQVNYSTTKAGLIGFTKSLAKELAPRNVLV 182 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N V+PG +TDM L +++K IPLG+ P+E+AN +LFL S+L Sbjct: 183 NAVAPGFIETDMTAVLS----------EEIKQKYKEQIPLGRFGSPEEVANVVLFLCSEL 232 Query: 230 ASHITLQDIVVDGGS 244 AS+IT + I V+GG Sbjct: 233 ASYITGEVIHVNGGM 247 >2HQ1-A nrPDB Length = 247 Score = 259 bits (663), Expect = 6e-70, Method: Composition-based stats. Identities = 75/257 (29%), Positives = 110/257 (42%), Gaps = 21/257 (8%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVT-----------GFDQAFTQEQYPFATE 49 M GK VTG+ +G+G A A GA + + F Sbjct: 1 MQLKGKTAIVTGSSRGLGKAIAWKLGNMGANIVLNGSPASTSLDATAEEFKAAGINVVVA 60 Query: 50 VMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 DV + V + + + R+D LVN AGI R ++S++DW N+ A+ Sbjct: 61 KGDVKNPEDVENMVKTAMDAFGRIDILVNNAGITRDTLMLKMSEKDWDDVLNTNLKSAYL 120 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 + +Q+ G I+ + S A G + Y ASKA L S+ E A G+ C Sbjct: 121 CTKAVSKIMLKQKSGKIINITSIAGIIGNAGQANYAASKAGLIGFTKSIAKEFAAKGIYC 180 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N V+PG TDM L E + IPL + P+E+AN + FLASD Sbjct: 181 NAVAPGIIKTDMTDVL----------PDKVKEMYLNNIPLKRFGTPEEVANVVGFLASDD 230 Query: 230 ASHITLQDIVVDGGSTL 246 +++IT Q I +DGG + Sbjct: 231 SNYITGQVINIDGGLVM 247 >3RSH-A nrPDB Length = 251 Score = 259 bits (662), Expect = 8e-70, Method: Composition-based stats. Identities = 74/253 (29%), Positives = 115/253 (45%), Gaps = 17/253 (6%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQY-------PFATEVMDV 53 M+ GK VTGA +GIG A A E GAKV G + + Q ++V Sbjct: 8 MNLEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMALNV 67 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 + + V + + E +D LVN AGI R ++ +E+W N+ F L + Sbjct: 68 TNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFRLSKA 127 Query: 114 TMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 + ++R G I+ V S G + Y A+KA + S+ E+A GV N V+ Sbjct: 128 VLRGMMKKRQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVASRGVTVNTVA 187 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 PG +TDM + L +P G++ P+EIA+ + FLAS A++I Sbjct: 188 PGFIETDMTKALNDEQRTA----------TLAQVPAGRLGDPREIASAVAFLASPEAAYI 237 Query: 234 TLQDIVVDGGSTL 246 T + + V+GG + Sbjct: 238 TGETLHVNGGMYM 250 >4JRO-A nrPDB Length = 271 Score = 259 bits (662), Expect = 9e-70, Method: Composition-based stats. Identities = 77/257 (29%), Positives = 110/257 (42%), Gaps = 21/257 (8%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVM--------- 51 M GK VTG +GIG A+ + GA + + A V Sbjct: 25 MTLQGKVAVVTGGSRGIGRDIAINLAKEGANIFFNYNGSPEAAEETAKLVAEHGVEVEAM 84 Query: 52 --DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 +VA A V ++ + R+D LVN AGI R ++ +++W +N+ G F Sbjct: 85 KANVAIAEDVDAFFKQAIERFGRVDILVNNAGITRDNLLMRMKEDEWDDVININLKGTFL 144 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 + +QR G I+ +AS G + Y ASKA + L + ELA G+ Sbjct: 145 CTKAVSRTMMKQRAGKIINMASVVGLIGNAGQANYVASKAGVIGLTKTTARELAPRGINV 204 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N V+PG TDM L E IPLG ++IAN +LFLASD Sbjct: 205 NAVAPGFITTDMTDKLDEKTK----------EAMLAQIPLGAYGTTEDIANAVLFLASDA 254 Query: 230 ASHITLQDIVVDGGSTL 246 + +IT Q + VDGG + Sbjct: 255 SKYITGQTLSVDGGMVM 271 >3OSU-A nrPDB Length = 246 Score = 258 bits (660), Expect = 2e-69, Method: Composition-based stats. Identities = 82/252 (32%), Positives = 119/252 (47%), Gaps = 21/252 (8%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV-----------MDVA 54 K+ VTGA +GIG + AL E G V ++ E+ +VA Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVA 64 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 DA +V + + ++++ LD LVN AGI R ++ +++W N+ G FN Q+ Sbjct: 65 DADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQKA 124 Query: 115 MNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSP 174 Q RQR GAI+ ++S G + Y A+KA + L S ELA G+ N V+P Sbjct: 125 TPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAVAP 184 Query: 175 GSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHIT 234 G +DM L EQ IPL + + +IANT+ FLASD A +IT Sbjct: 185 GFIVSDMTDALSDE----------LKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYIT 234 Query: 235 LQDIVVDGGSTL 246 Q I V+GG + Sbjct: 235 GQTIHVNGGMYM 246 >2UVD-A nrPDB Length = 246 Score = 258 bits (659), Expect = 2e-69, Method: Composition-based stats. Identities = 76/255 (29%), Positives = 114/255 (44%), Gaps = 21/255 (8%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV-----------M 51 GK VTGA +GIG A A+ + GA V Q+ E+ Sbjct: 2 LKGKVALVTGASRGIGRAIAIDLAKQGANVVVNYAGNEQKANEVVDEIKKLGSDAIAVRA 61 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 DVA+A V + ++ + ++D LVN AG+ + ++ +E+W N+ G F Sbjct: 62 DVANAEDVTNMVKQTVDVFGQVDILVNNAGVTKDNLLMRMKEEEWDTVINTNLKGVFLCT 121 Query: 112 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 171 + RQR G IV +AS T G + Y A+KA + L + ELA + N Sbjct: 122 KAVSRFMMRQRHGRIVNIASVVGVTGNPGQANYVAAKAGVIGLTKTSAKELASRNITVNA 181 Query: 172 VSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLAS 231 ++PG TDM L + AE ++ IP + Q+IAN + F ASD + Sbjct: 182 IAPGFIATDMTDVLDENIKAEMLKL----------IPAAQFGEAQDIANAVTFFASDQSK 231 Query: 232 HITLQDIVVDGGSTL 246 +IT Q + VDGG + Sbjct: 232 YITGQTLNVDGGMVM 246 >2C07-A nrPDB Length = 285 Score = 255 bits (652), Expect = 1e-68, Method: Composition-based stats. Identities = 64/252 (25%), Positives = 111/252 (44%), Gaps = 20/252 (7%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQ----------AFTQEQYPFATEVMDV 53 K VTGAG+GIG A ++ + V + Y + DV Sbjct: 43 ENKVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKSFGYESSGYAGDV 102 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 + ++++V ++L E + +D LVN AGI R ++ ++W+ N+ F + Q Sbjct: 103 SKKEEISEVINKILTEHKNVDILVNNAGITRDNLFLRMKNDEWEDVLRTNLNSLFYITQP 162 Query: 114 TMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 + R G I+ ++S T +G + Y +SKA + S+ ELA + N ++ Sbjct: 163 ISKRMINNRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKELASRNITVNAIA 222 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 PG +DM + + IP G++ P+E+AN FL+SD + +I Sbjct: 223 PGFISSDMTDKIS----------EQIKKNIISNIPAGRMGTPEEVANLACFLSSDKSGYI 272 Query: 234 TLQDIVVDGGST 245 + V+DGG + Sbjct: 273 NGRVFVIDGGLS 284 >3LYL-A nrPDB Length = 247 Score = 253 bits (647), Expect = 5e-68, Method: Composition-based stats. Identities = 72/257 (28%), Positives = 120/257 (46%), Gaps = 20/257 (7%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTG----------FDQAFTQEQYPFATEV 50 M + K VTGA +GIG+ A A GA V G F+ + ++ + V Sbjct: 1 MSLNEKVALVTGASRGIGFEVAHALASKGATVVGTATSQASAEKFENSMKEKGFKARGLV 60 Query: 51 MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 ++++D + + AE +D LVN AGI R ++S+++WQ N+ F + Sbjct: 61 LNISDIESIQNFFAEIKAENLAIDILVNNAGITRDNLMMRMSEDEWQSVINTNLSSIFRM 120 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 ++ + ++R G I+++ S G + Y A+KA + + S+ E+A + N Sbjct: 121 SKECVRGMMKKRWGRIISIGSVVGSAGNPGQTNYCAAKAGVIGFSKSLAYEVASRNITVN 180 Query: 171 VVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 230 VV+PG TDM L + IP G+I P++IA + FLAS+ A Sbjct: 181 VVAPGFIATDMTDKLTDEQKS----------FIATKIPSGQIGEPKDIAAAVAFLASEEA 230 Query: 231 SHITLQDIVVDGGSTLG 247 +IT Q + V+GG + Sbjct: 231 KYITGQTLHVNGGMYMA 247 >1Q7C-A nrPDB Length = 244 Score = 252 bits (644), Expect = 1e-67, Method: Composition-based stats. Identities = 81/253 (32%), Positives = 120/253 (47%), Gaps = 17/253 (6%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAF-------TQEQYPFATEVMDV 53 M+F GK VTGA +GIG A A GAKV G + +++V Sbjct: 1 MNFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNV 60 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 D A + V +++ AE +D LVN AGI R ++ E+W N+ F L + Sbjct: 61 TDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFRLSKA 120 Query: 114 TMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 M ++R G I+T+ S G + + A+KA L + S+ E+A G+ NVV+ Sbjct: 121 VMRAMMKKRHGRIITIGSVVGTMGNGGQANFAAAKAGLIGFSKSLAREVASRGITVNVVA 180 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 PG +TDM R L A +P G++ QEIAN + FLASD A++I Sbjct: 181 PGFIETDMTRALSDDQRA----------GILAQVPAGRLGGAQEIANAVAFLASDEAAYI 230 Query: 234 TLQDIVVDGGSTL 246 T + + V+GG + Sbjct: 231 TGETLHVNGGMYM 243 >5ITV-A nrPDB Length = 255 Score = 252 bits (644), Expect = 1e-67, Method: Composition-based stats. Identities = 73/253 (28%), Positives = 113/253 (44%), Gaps = 10/253 (3%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATE--------VMD 52 M+ + K V +TG GIGYA AF+ A V D Q + E D Sbjct: 3 MNLTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRKENNDRLHFVQTD 62 Query: 53 VADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQ 112 + D A + + LD L+N AGI + ++ DW + VN+ G F + + Sbjct: 63 ITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMSK 122 Query: 113 QTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVV 172 + G I+ S + AY ASK + L S+ ++ A +R N V Sbjct: 123 HALKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIRVNCV 182 Query: 173 SPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASH 232 PG DT + ++ ++ E + ++ PL ++ +P+EIAN +LFLASDL+S+ Sbjct: 183 CPGIIDTPLNEKSFLENN--EGTLEEIKKEKAKVNPLLRLGKPEEIANVMLFLASDLSSY 240 Query: 233 ITLQDIVVDGGST 245 +T I DGG T Sbjct: 241 MTGSAITADGGYT 253 >5CDY-A nrPDB Length = 244 Score = 250 bits (640), Expect = 3e-67, Method: Composition-based stats. Identities = 79/253 (31%), Positives = 117/253 (46%), Gaps = 17/253 (6%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAF-------TQEQYPFATEVMDV 53 M F GK VTGA +GIG A A VE GA V G + +++V Sbjct: 1 MSFEGKIALVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGKGLMLNV 60 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 D + V + AE +D LVN AGI R ++ ++WQ N+ F L + Sbjct: 61 VDPTSIDTVLATIRAEFGEVDILVNNAGITRDNLLMRMKDDEWQDIIDTNLTSVFRLSKA 120 Query: 114 TMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 M ++R G I+T+ S G Y A+KA + + S+ E+A G+ NVV+ Sbjct: 121 VMRAMMKKRFGRIITIGSVVGTMGNAGQVNYAAAKAGVIGFSKSLAREVASRGITVNVVA 180 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 PG +TDM RTL A +P ++ +EIA+ + FLASD AS+I Sbjct: 181 PGFIETDMTRTLTDDQRA----------GILAQVPANRLGDAKEIASAVAFLASDEASYI 230 Query: 234 TLQDIVVDGGSTL 246 + + + V+GG + Sbjct: 231 SGETLHVNGGMYM 243 >3FTP-A nrPDB Length = 270 Score = 250 bits (640), Expect = 3e-67, Method: Composition-based stats. Identities = 75/254 (29%), Positives = 111/254 (43%), Gaps = 20/254 (7%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTG----------FDQAFTQEQYPFATEVMD 52 + VTGA +GIG A AL GA V G AF Q V++ Sbjct: 26 LDKQVAIVTGASRGIGRAIALELARRGAMVIGTATTEAGAEGIGAAFKQAGLEGRGAVLN 85 Query: 53 VADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQ 112 V DA V + + L E L+ LVN AGI + ++ ++W N+ F L + Sbjct: 86 VNDATAVDALVESTLKEFGALNVLVNNAGITQDQLAMRMKDDEWDAVIDTNLKAVFRLSR 145 Query: 113 QTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVV 172 + + RGG IV + S G Y A+KA + + ++ E+ G+ N V Sbjct: 146 AVLRPMMKARGGRIVNITSVVGSAGNPGQVNYAAAKAGVAGMTRALAREIGSRGITVNCV 205 Query: 173 SPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASH 232 +PG DTDM + L K IPLG++ P++IA+ + FLAS A + Sbjct: 206 APGFIDTDMTKGLPQEQQTA----------LKTQIPLGRLGSPEDIAHAVAFLASPQAGY 255 Query: 233 ITLQDIVVDGGSTL 246 IT + V+GG + Sbjct: 256 ITGTTLHVNGGMFM 269 >4M8S-A nrPDB Length = 248 Score = 249 bits (637), Expect = 7e-67, Method: Composition-based stats. Identities = 79/253 (31%), Positives = 114/253 (45%), Gaps = 18/253 (7%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQY--------PFATEVMDV 53 D SGK VTGA +GIG A A AGAKV G + + V++ Sbjct: 5 DLSGKIALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGGEGRVLNS 64 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 A+ V + + +LD LVN AGI R ++ +E+W VN+ F + Sbjct: 65 AEPETVENLIADIEKTFGKLDILVNNAGITRDNLLMRMKEEEWDDIMQVNLKSVFRASKA 124 Query: 114 TMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 + +QR G I+ + S G + Y A+KA L + S+ E+ G+ N V+ Sbjct: 125 VLRGMMKQRAGRIINITSVVGVMGNAGQTNYAAAKAGLIGFSKSMAREVGSRGITVNCVA 184 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 PG DTDM R L + F LG+ Q+IA+ +LFLASD A +I Sbjct: 185 PGFIDTDMTRAL----------PEETRQTFTAQTALGRFGDAQDIADAVLFLASDQAKYI 234 Query: 234 TLQDIVVDGGSTL 246 T Q + V+GG + Sbjct: 235 TGQTLHVNGGMLM 247 >3EMK-A nrPDB Length = 246 Score = 248 bits (633), Expect = 2e-66, Method: Composition-based stats. Identities = 72/252 (28%), Positives = 114/252 (45%), Gaps = 17/252 (6%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTG-------FDQAFTQEQYPFATEVMDVA 54 D +G+ VTGA G+G A A A GA V + + +++ Sbjct: 4 DLTGRKALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELGERIFVFPANLS 63 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 D V + Q+ E +D LVN AGI R G ++S EDW VN+ FNL ++ Sbjct: 64 DREAVKALGQKAEEEMGGVDILVNNAGITRDGLFVRMSDEDWDAVLTVNLTSVFNLTREL 123 Query: 115 MNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSP 174 + R+R G I+ + S T G + Y ASKA L + S+ E+A V N ++P Sbjct: 124 THPMMRRRNGRIINITSIVGVTGNPGQANYCASKAGLIGFSKSLAQEIASRNVTVNCIAP 183 Query: 175 GSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHIT 234 G ++ M L + IP+ ++ +IA +++LASD A+++T Sbjct: 184 GFIESAMTGKLNEKQK----------DAIMGNIPMKRMGVGADIAAAVVYLASDEAAYVT 233 Query: 235 LQDIVVDGGSTL 246 Q + V+GG + Sbjct: 234 GQTLHVNGGMAM 245 >2NM0-A nrPDB Length = 253 Score = 246 bits (628), Expect = 8e-66, Method: Composition-based stats. Identities = 81/242 (33%), Positives = 119/242 (49%), Gaps = 11/242 (4%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQR 65 ++V VTG +GIG A A AF +AG KV ++ + F D+ D QV Q + Sbjct: 22 RSVLVTGGNRGIGLAIARAFADAGDKVAITYRSGEPPEG-FLAVKCDITDTEQVEQAYKE 80 Query: 66 LLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGA 125 + ++ L+ AG+ + ++S+ED+ N+ G F + ++ R + G Sbjct: 81 IEETHGPVEVLIANAGVTKDQLLMRMSEEDFTSVVETNLTGTFRVVKRANRAMLRAKKGR 140 Query: 126 IVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQRTL 185 +V ++S G + Y ASKA L A S+ EL + NVV+PG DTDM + L Sbjct: 141 VVLISSVVGLLGSAGQANYAASKAGLVGFARSLARELGSRNITFNVVAPGFVDTDMTKVL 200 Query: 186 WVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDGGST 245 A +PLG+ ARP+EIA T+ FLASD AS+IT I VDGG Sbjct: 201 TDEQRA----------NIVSQVPLGRYARPEEIAATVRFLASDDASYITGAVIPVDGGLG 250 Query: 246 LG 247 +G Sbjct: 251 MG 252 >4NBT-A nrPDB Length = 240 Score = 245 bits (627), Expect = 9e-66, Method: Composition-based stats. Identities = 80/248 (32%), Positives = 125/248 (50%), Gaps = 13/248 (5%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV-MDVADAAQVA 60 GK +TG KG+G A ALA+ E GAKV D +P + ++V D V Sbjct: 3 KLEGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDLGDLTYSHPNVEGMYLNVTDVTGVE 62 Query: 61 QVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRR 120 + Q ++ + ++D LVN AGI + T ++++ W VN+ G FNL + Q + Sbjct: 63 KFYQSVIDKYGKIDILVNNAGITKDAMTRKMTEAQWDAVIDVNLKGVFNLTRLVGPQMQT 122 Query: 121 QRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSG--VRCNVVSPGSTD 178 G+I+ ++S IG + Y A+KA + L ++ E A G VR N ++PG Sbjct: 123 NGYGSIINISSVVGVFGNIGQANYAATKAGVIGLTMTWAKEFALKGANVRVNAIAPGYIM 182 Query: 179 TDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDI 238 TD+ +T+ + ++F L ++ +P+EIA LFLASD AS++T Q I Sbjct: 183 TDILKTV----------PQDLLDKFAALTMLNRLGQPEEIAKVALFLASDDASYVTGQTI 232 Query: 239 VVDGGSTL 246 V+GG L Sbjct: 233 NVNGGMRL 240 >3WOH-A nrPDB Length = 251 Score = 245 bits (625), Expect = 2e-65, Method: Composition-based stats. Identities = 81/255 (31%), Positives = 118/255 (46%), Gaps = 23/255 (9%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV-----------M 51 SGK VTG +G+G A AL GA V + E+ Sbjct: 9 LSGKVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLGGTARSYRC 68 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 DV+DA QV + + + A+ +D LVN AGI+R G + ED+ N+ GAF Sbjct: 69 DVSDAEQVTRCVKAVTADLGPVDILVNNAGIIRDGLAASIKDEDYDAVMNTNLKGAFLFI 128 Query: 112 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 171 + F R+R G+I+ ++S + G + Y ++KA L L S+ ELA VRCN Sbjct: 129 KACYFGFIRKRSGSIINISSVSGVFGSAGQANYASAKAGLIGLTKSIAKELAERNVRCNA 188 Query: 172 VSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLAS 231 V+PG TDM + L + +P+ + RP E+A + FLA D +S Sbjct: 189 VAPGLIATDMTQDLVDDSKRLD------------PVPMRRFGRPDEVAGLVAFLAGDESS 236 Query: 232 HITLQDIVVDGGSTL 246 +IT Q + VDGG + Sbjct: 237 YITGQVVCVDGGMAM 251 >3F9I-A nrPDB Length = 249 Score = 243 bits (621), Expect = 5e-65, Method: Composition-based stats. Identities = 69/253 (27%), Positives = 116/253 (45%), Gaps = 21/253 (8%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQ-------YPFATEVMDV 53 +D +GK +TGA GIG A A + G+KV + + + EV ++ Sbjct: 10 IDLTGKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYTIEVCNL 69 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 A+ + + + + LD LV AGI ++ +D+ + +N+ F L ++ Sbjct: 70 ANKEECSNLISKT----SNLDILVCNAGITSDTLAIRMKDQDFDKVIDINLKANFILNRE 125 Query: 114 TMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 + + ++R G I+ ++S G + Y ASKA L + S+ E+A G+ N V+ Sbjct: 126 AIKKMIQKRYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYEVATRGITVNAVA 185 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 PG +DM L E IPLG P+++A + FLAS+ AS+I Sbjct: 186 PGFIKSDMTDKLN----------EKQREAIVQKIPLGTYGIPEDVAYAVAFLASNNASYI 235 Query: 234 TLQDIVVDGGSTL 246 T Q + V+GG + Sbjct: 236 TGQTLHVNGGMLM 248 >4DMM-A nrPDB Length = 269 Score = 240 bits (612), Expect = 5e-64, Method: Composition-based stats. Identities = 79/257 (30%), Positives = 114/257 (44%), Gaps = 25/257 (9%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFT-----------QEQYPFATEVM 51 + + VTGA +GIG A AL AGAKV + Sbjct: 26 LTDRIALVTGASRGIGRAIALELAAAGAKVAVNYASSAGAADEVVAAIAAAGGEAFAVKA 85 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 DV+ ++V + ++ RLD LVN AGI R ++ ++DWQ +N+GG F Sbjct: 86 DVSQESEVEALFAAVIERWGRLDVLVNNAGITRDTLLLRMKRDDWQSVLDLNLGGVFLCS 145 Query: 112 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 171 + +QR G I+ +AS G + Y A+KA + L +V ELA G+ N Sbjct: 146 RAAAKIMLKQRSGRIINIASVVGEMGNPGQANYSAAKAGVIGLTKTVAKELASRGITVNA 205 Query: 172 VSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASD-LA 230 V+PG TDM L E+ IPLG+ E+A + FLA+D A Sbjct: 206 VAPGFIATDMTSELA-------------AEKLLEVIPLGRYGEAAEVAGVVRFLAADPAA 252 Query: 231 SHITLQDIVVDGGSTLG 247 ++IT Q I +DGG + Sbjct: 253 AYITGQVINIDGGLVMA 269 >4BO1-A nrPDB Length = 269 Score = 238 bits (609), Expect = 1e-63, Method: Composition-based stats. Identities = 71/256 (27%), Positives = 109/256 (42%), Gaps = 20/256 (7%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTG----------FDQAFTQEQYPFATEV 50 M GK VTGA +GIG A AL GA V G + A V Sbjct: 23 MSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLV 82 Query: 51 MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 +DV+ VA + + + +VN AGI R ++ ++W N+ + L Sbjct: 83 LDVSSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEWFDVVNTNLNSLYRL 142 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 + + + R G I+ + S G + Y A+KA L+ ++ E+ + N Sbjct: 143 SKAVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAITVN 202 Query: 171 VVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 230 V+PG DTDM R L E IPLG++ + +EIA + FLASD A Sbjct: 203 AVAPGFIDTDMTREL----------PEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGA 252 Query: 231 SHITLQDIVVDGGSTL 246 +++T + V+GG + Sbjct: 253 AYVTGATVPVNGGMYM 268 >2PH3-A nrPDB Length = 245 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 70/252 (27%), Positives = 106/252 (42%), Gaps = 22/252 (8%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYP------------FATEVMDV 53 + +TGA +GIG A AL E G + ++ A ++ Sbjct: 2 RKALITGASRGIGRAIALRLAEDGFALAIHYGQNREKAEEVAEEARRRGSPLVAVLGANL 61 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 +A + + LD LVN AGI R ++ EDW+ N+ F ++ Sbjct: 62 LEAEAATALVHQAAEVLGGLDTLVNNAGITRDTLLVRMKDEDWEAVLEANLSAVFRTTRE 121 Query: 114 TMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 + + R G IV + S G + Y ASKA L +V E A G+ N V+ Sbjct: 122 AVKLMMKARFGRIVNITSVVGILGNPGQANYVASKAGLIGFTRAVAKEYAQRGITVNAVA 181 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 PG +T+M E+ + E + IP G+ RP+E+A + FL S+ A +I Sbjct: 182 PGFIETEMT----------ERLPQEVKEAYLKQIPAGRFGRPEEVAEAVAFLVSEKAGYI 231 Query: 234 TLQDIVVDGGST 245 T Q + VDGG T Sbjct: 232 TGQTLCVDGGLT 243 >5OVL-A nrPDB Length = 300 Score = 237 bits (606), Expect = 3e-63, Method: Composition-based stats. Identities = 75/245 (30%), Positives = 116/245 (47%), Gaps = 11/245 (4%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQV 62 F ++V VTG +GIG A A G KV + F + DV D+A V + Sbjct: 66 FVSRSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDLFGVQ-CDVTDSAAVDRA 124 Query: 63 CQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQR 122 + + ++ LV AGI + ++++E +++ N+ GAF Q+ +R+R Sbjct: 125 FKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRASRTMQRKR 184 Query: 123 GGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQ 182 G I+ + S + + Y A+KA L +A S+ ELA +GV NVV+PG DT+M Sbjct: 185 FGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPGYIDTEMT 244 Query: 183 RTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDG 242 R L A IP ++ +E+A + FLAS+ AS+I I VDG Sbjct: 245 RALDERIQAGALDF----------IPAKRVGTAEEVAGAVSFLASEDASYIAGAVIPVDG 294 Query: 243 GSTLG 247 G +G Sbjct: 295 GMGMG 299 >3O4R-A nrPDB Length = 261 Score = 237 bits (604), Expect = 5e-63, Method: Composition-based stats. Identities = 68/252 (26%), Positives = 114/252 (45%), Gaps = 19/252 (7%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQ----------AFTQEQYPFATEVMD 52 + K VT + GIG+A A + GA V + E V Sbjct: 13 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 72 Query: 53 VADAAQVAQVCQRLLAETERLDALVNAAGILRM-GATDQLSKEDWQQTFAVNVGGAFNLF 111 V A ++ + +D LV+ A + G+ +++E W +T +NV + Sbjct: 73 VGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMT 132 Query: 112 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 171 + + + ++ GG++V V+S AA +P G S Y SK AL L ++ +ELA +R N Sbjct: 133 KAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNC 192 Query: 172 VSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLAS 231 ++PG T R LW+ + E E K + + ++ P++ A + FL S+ AS Sbjct: 193 LAPGLIKTSFSRMLWMDKEKE--------ESMKETLRIRRLGEPEDCAGIVSFLCSEDAS 244 Query: 232 HITLQDIVVDGG 243 +IT + +VV GG Sbjct: 245 YITGETVVVGGG 256 >3GRP-A nrPDB Length = 266 Score = 236 bits (603), Expect = 6e-63, Method: Composition-based stats. Identities = 70/252 (27%), Positives = 113/252 (44%), Gaps = 17/252 (6%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDV-------A 54 +G+ VTGA GIG A A F GA V + + A DV + Sbjct: 24 KLTGRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADLGKDVFVFSANLS 83 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 D + Q+ + E E +D LVN AGI R G ++ +DW AVN+ A L ++ Sbjct: 84 DRKSIKQLAEVAEREMEGIDILVNNAGITRDGLFVRMQDQDWDDVLAVNLTAASTLTREL 143 Query: 115 MNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSP 174 ++ R+R G I+ + S G + Y A+KA L + ++ E+A + N ++P Sbjct: 144 IHSMMRRRYGRIINITSIVGVVGNPGQTNYCAAKAGLIGFSKALAQEIASRNITVNCIAP 203 Query: 175 GSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHIT 234 G + M L E IP+ ++ +EIA ++LASD A+++T Sbjct: 204 GFIKSAMTDKLNEKQK----------EAIMAMIPMKRMGIGEEIAFATVYLASDEAAYLT 253 Query: 235 LQDIVVDGGSTL 246 Q + ++GG + Sbjct: 254 GQTLHINGGMAM 265 >3OEC-A nrPDB Length = 317 Score = 235 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 71/274 (25%), Positives = 112/274 (40%), Gaps = 34/274 (12%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFA-------------- 47 GK ++TGA +G G A+ + GA + D Q +A Sbjct: 43 RLQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKETVRLV 102 Query: 48 --------TEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQT 99 DV D A + V LAE +D LV+ GI G L+ + W Sbjct: 103 EEQGRRIIARQADVRDLASLQAVVDEALAEFGHIDILVSNVGISNQGEVVSLTDQQWSDI 162 Query: 100 FAVNVGGAFNLFQQTMNQFRRQR-GGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSV 158 N+ GA++ + + + GG+++ V+S G S Y ASK ++ L LS+ Sbjct: 163 LQTNLIGAWHACRAVLPSMIERGQGGSVIFVSSTVGLRGAPGQSHYAASKHGVQGLMLSL 222 Query: 159 GLELAGSGVRCNVVSPGSTDTDMQRTL--------WVSDDAEEQRIRGFGEQFKLGIPLG 210 E+ +R N V+PG+ +T+M + + E F + L IP Sbjct: 223 ANEVGRHNIRVNSVNPGAVNTEMALNEKLLKMFLPHLENPTREDAAELFSQLTLLPIP-- 280 Query: 211 KIARPQEIANTILFLASDLASHITLQDIVVDGGS 244 P++++N + +LASD A +I I VDGG Sbjct: 281 -WVEPEDVSNAVAWLASDEARYIHGAAIPVDGGQ 313 >1AE1-A nrPDB Length = 273 Score = 234 bits (598), Expect = 2e-62, Method: Composition-based stats. Identities = 66/255 (25%), Positives = 111/255 (43%), Gaps = 15/255 (5%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQ----------EQYPFATEVM 51 G VTG KGIGYA GA+V + + + V Sbjct: 18 SLKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREKGLNVEGSVC 77 Query: 52 DVADAAQVAQVCQRLLAET-ERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 D+ + ++ Q + +L+ LVN AG++ +++D+ N A++L Sbjct: 78 DLLSRTERDKLMQTVAHVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFEAAYHL 137 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 Q + + G ++ ++S A + +S Y ASK A+ + S+ E A +R N Sbjct: 138 SQIAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLACEWAKDNIRVN 197 Query: 171 VVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 230 V+PG T + T + +++ I + F + P+G+ +PQE++ I FL A Sbjct: 198 SVAPGVILTPLVETAIKKNPHQKEEI----DNFIVKTPMGRAGKPQEVSALIAFLCFPAA 253 Query: 231 SHITLQDIVVDGGST 245 S+IT Q I DGG T Sbjct: 254 SYITGQIIWADGGFT 268 >3EZL-A nrPDB Length = 256 Score = 233 bits (596), Expect = 4e-62, Method: Composition-based stats. Identities = 66/258 (25%), Positives = 112/258 (43%), Gaps = 21/258 (8%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTG-----------FDQAFTQEQYPFATE 49 M S + +VTG GIG + + G +V + + + F Sbjct: 9 MVMSQRIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYAS 68 Query: 50 VMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 +V D Q ++ AE +D LVN AGI R ++++EDWQ N+ FN Sbjct: 69 EGNVGDWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTREDWQAVIDTNLTSLFN 128 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 + +Q ++ + G I+ ++S + G + Y +KA + +S+ E+A GV Sbjct: 129 VTKQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVATKGVTV 188 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N VSPG TDM + + E+ IP+ ++ P EI + + +LAS+ Sbjct: 189 NTVSPGYIGTDMVKAIR----------PDVLEKIVATIPVRRLGSPDEIGSIVAWLASEE 238 Query: 230 ASHITLQDIVVDGGSTLG 247 + T D ++GG +G Sbjct: 239 SGFSTGADFSLNGGLHMG 256 >4IIN-A nrPDB Length = 271 Score = 233 bits (595), Expect = 5e-62, Method: Composition-based stats. Identities = 73/257 (28%), Positives = 117/257 (45%), Gaps = 21/257 (8%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQA-----------FTQEQYPFATE 49 M F+GKNV +TGA KGIG A G KV ++ ++ Y A Sbjct: 25 MQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVI 84 Query: 50 VMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 D A + + Q ++ L LVN AG++R ++ ED+ N+ AF Sbjct: 85 KFDAASESDFIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLTSAFI 144 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 ++ + + R G++V VAS +G + Y ASK + +++ S E A +R Sbjct: 145 GCREALKVMSKSRFGSVVNVASIIGERGNMGQTNYSASKGGMIAMSKSFAYEGALRNIRF 204 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N V+PG +TDM L A+ + IPL ++ +E+A + FL SD Sbjct: 205 NSVTPGFIETDMNANLKDELKAD----------YVKNIPLNRLGSAKEVAEAVAFLLSDH 254 Query: 230 ASHITLQDIVVDGGSTL 246 +S+IT + + V+GG + Sbjct: 255 SSYITGETLKVNGGLYM 271 >4NBV-A nrPDB Length = 246 Score = 233 bits (594), Expect = 6e-62, Method: Composition-based stats. Identities = 73/256 (28%), Positives = 109/256 (42%), Gaps = 20/256 (7%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYP----------FATEV 50 M G+ +TGA GIG+ATA F E GA V D + + + Sbjct: 1 MKLQGRVAIITGAAAGIGFATAQRFAEDGAIVVLCDVQEARVREAAARLAATGATVSAYR 60 Query: 51 MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 +DV +V + +LA +R+D LVN AGI + ++++ + VN+ G FN Sbjct: 61 VDVTRRDEVDAMVAAVLAAHQRVDILVNNAGITKDARLAKMTEAQFDAVIDVNLKGVFNC 120 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 Q Q G I+ +S G + Y ASK + + EL GVR N Sbjct: 121 AQAVAGLMTEQGKGVILNASSVVGLYGNFGQTNYAASKFGVIGFTKTWARELGPKGVRVN 180 Query: 171 VVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 230 V PG +T++ +T+ + L ++A P EIA+ FLASD A Sbjct: 181 AVCPGFVNTEILQTV----------PDKVLDGMTSSCWLRRLAEPAEIASIYAFLASDDA 230 Query: 231 SHITLQDIVVDGGSTL 246 S++ I GG +L Sbjct: 231 SYVNGVAIEASGGMSL 246 >4KMS-A nrPDB Length = 249 Score = 232 bits (593), Expect = 8e-62, Method: Composition-based stats. Identities = 68/247 (27%), Positives = 110/247 (44%), Gaps = 17/247 (6%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGF------DQAFTQEQYPFATEVMDVADAAQVA 60 VTG +GIG ATAL G V +E+Y T+ +VAD + Sbjct: 12 IAIVTGGTRGIGKATALELKNKGLTVVANFFSNYDAAKEMEEKYGIKTKCWNVADFEECR 71 Query: 61 QVCQRLLAETER-LDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFR 119 Q + + E ++ + LVN AGI + ++S +DW VN+ FN+ M Q R Sbjct: 72 QAVKEIEEEFKKPVSILVNNAGITKDKMLHRMSHQDWNDVINVNLNSCFNMSSSVMEQMR 131 Query: 120 RQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDT 179 Q G IV ++S A ++G + Y A+KA + ++ E A + N ++PG T Sbjct: 132 NQDYGRIVNISSINAQAGQVGQTNYSAAKAGIIGFTKALARETASKNITVNCIAPGYIAT 191 Query: 180 DMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIV 239 +M + + IP ++ +P+EIA + FL + A IT + I Sbjct: 192 EMVGAV----------PEDVLAKIINSIPKKRLGQPEEIARAVAFLVDENAGFITGETIS 241 Query: 240 VDGGSTL 246 ++GG + Sbjct: 242 INGGHNM 248 >5YSS-A nrPDB Length = 256 Score = 232 bits (592), Expect = 1e-61, Method: Composition-based stats. Identities = 65/254 (25%), Positives = 105/254 (41%), Gaps = 9/254 (3%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGA--------KVTGFDQAFTQEQYPFATEVMD 52 M+ +GK VTG+ GIG A +AGA V A Q D Sbjct: 1 MNLTGKTALVTGSTSGIGLGIAQVLAQAGATLILNGFGDVDAAKDAVAQYGKTPGYHGAD 60 Query: 53 VADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQ 112 ++D AQ+A + + +E +D L+N AGI + + + W A+N+ F+ + Sbjct: 61 LSDEAQIADMMRYAESEFGGVDILINNAGIQHVSPIETFPVDKWNAIIAINLSSVFHTTR 120 Query: 113 QTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVV 172 + R + G I+ +AS SAY A+K + L ++ LE A + + CN + Sbjct: 121 LALPGMRARNWGRIINIASVHGLVASKEKSAYVAAKHGVVGLTKTIALETAQTEITCNAL 180 Query: 173 SPGSTDTDMQRTLWVSDDAEEQRIRGFGEQ-FKLGIPLGKIARPQEIANTILFLASDLAS 231 PG T + + AE + P + P+++ N LFL SD A+ Sbjct: 181 CPGWVLTPLVQQQIDKRIAEGAEPEAARDALLAEKQPSREFVTPEQLGNLALFLCSDGAA 240 Query: 232 HITLQDIVVDGGST 245 + +DGG Sbjct: 241 QVRGVAWNMDGGWV 254 >5OVJ-A nrPDB Length = 256 Score = 232 bits (592), Expect = 1e-61, Method: Composition-based stats. Identities = 75/245 (30%), Positives = 116/245 (47%), Gaps = 11/245 (4%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQV 62 F ++V VTG +GIG A A G KV + F + DV D+A V + Sbjct: 22 FVSRSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDLFGVQ-CDVTDSAAVDRA 80 Query: 63 CQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQR 122 + + ++ LV AGI + ++++E +++ N+ GAF Q+ +R+R Sbjct: 81 FKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRASRTMQRKR 140 Query: 123 GGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQ 182 G I+ + S + + Y A+KA L +A S+ ELA +GV NVV+PG DT+M Sbjct: 141 FGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPGYIDTEMT 200 Query: 183 RTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDG 242 R L A IP ++ +E+A + FLAS+ AS+I I VDG Sbjct: 201 RALDERIQAGALDF----------IPAKRVGTAEEVAGAVSFLASEDASYIAGAVIPVDG 250 Query: 243 GSTLG 247 G +G Sbjct: 251 GMGMG 255 >4K6F-A nrPDB Length = 255 Score = 232 bits (592), Expect = 1e-61, Method: Composition-based stats. Identities = 67/255 (26%), Positives = 113/255 (44%), Gaps = 20/255 (7%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVT--------GFDQAFTQ---EQYPFATEVM 51 + + VTG G+G A ++ +AG +V G D+ T+ F + Sbjct: 9 MTKRIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNTGADRWLTEMHAAGREFHAYPV 68 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 DVAD Q ++++ + +D LVN AGI R +L K +W N+ FN+ Sbjct: 69 DVADHDSCQQCIEKIVRDVGPVDILVNNAGITRDMTLRKLDKVNWDAVIRTNLDSVFNMT 128 Query: 112 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 171 + + + G IV ++S +G + Y A+KA + S+ LE+A GV N Sbjct: 129 KPVCDGMVERGWGRIVNISSVNGSKGSVGQTNYAAAKAGMHGFTKSLALEIARKGVTVNT 188 Query: 172 VSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLAS 231 VSPG T M + + IP G++ +P+E+A + +L S+ A Sbjct: 189 VSPGYLATKMVTAIPQ---------DILDTKILPQIPAGRLGKPEEVAALVAYLCSEEAG 239 Query: 232 HITLQDIVVDGGSTL 246 +T +I ++GG + Sbjct: 240 FVTGSNIAINGGQHM 254 >4RZH-A nrPDB Length = 247 Score = 230 bits (587), Expect = 4e-61, Method: Composition-based stats. Identities = 83/256 (32%), Positives = 117/256 (45%), Gaps = 25/256 (9%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV-----------M 51 + + VTGA +GIG ATALA G KV + E+ Sbjct: 4 LTAQVALVTGASRGIGKATALALAATGMKVVVNYAQSSTAADAVVAEIIANGGEAIAVQA 63 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 +VA+A +V Q+ + L + R+D LVN AGI R ++ EDWQ +N+ G F Sbjct: 64 NVANADEVDQLIKTTLDKFSRIDVLVNNAGITRDTLLLRMKLEDWQAVIDLNLTGVFLCT 123 Query: 112 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 171 + +Q+ G I+ + S A G + Y A+KA + +V ELA GV N Sbjct: 124 KAVSKLMLKQKSGRIINITSVAGMMGNPGQANYSAAKAGVIGFTKTVAKELASRGVTVNA 183 Query: 172 VSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASD-LA 230 V+PG TDM L E IPL + +P+E+A TI FLA+D A Sbjct: 184 VAPGFIATDMTENLN-------------AEPILQFIPLARYGQPEEVAGTIRFLATDPAA 230 Query: 231 SHITLQDIVVDGGSTL 246 ++IT Q VDGG + Sbjct: 231 AYITGQTFNVDGGMVM 246 >2EW8-A nrPDB Length = 249 Score = 230 bits (586), Expect = 6e-61, Method: Composition-based stats. Identities = 65/252 (25%), Positives = 101/252 (40%), Gaps = 16/252 (6%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQY--------PFATEVMDV 53 K +TG GIG A A F GA + D E T DV Sbjct: 4 RLKDKLAVITGGANGIGRAIAERFAVEGADIAIADLVPAPEAEAAIRNLGRRVLTVKCDV 63 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 + V +++++ R D LVN AGI + D+L+ E W++TF +NV F + + Sbjct: 64 SQPGDVEAFGKQVISTFGRCDILVNNAGIYPLIPFDELTFEQWKKTFEINVDSGFLMAKA 123 Query: 114 TMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 + +R G I+ + S + Y ++KAA ++ +L G+ N ++ Sbjct: 124 FVPGMKRNGWGRIINLTSTTYWLKIEAYTHYISTKAANIGFTRALASDLGKDGITVNAIA 183 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 P T +S + IP ++ P ++ FLASD AS I Sbjct: 184 PSLVRTATTEASALS------AMFDVLPNMLQAIP--RLQVPLDLTGAAAFLASDDASFI 235 Query: 234 TLQDIVVDGGST 245 T Q + VDGG Sbjct: 236 TGQTLAVDGGMV 247 >1GEE-A nrPDB Length = 261 Score = 229 bits (585), Expect = 8e-61, Method: Composition-based stats. Identities = 69/257 (26%), Positives = 115/257 (44%), Gaps = 20/257 (7%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV----------- 50 D GK V +TG+ G+G + A+ F AKV ++ E E+ Sbjct: 4 DLEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKVGGEAIAVK 63 Query: 51 MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 DV + V + Q + E +LD ++N AG+ ++ ++S DW + N+ GAF Sbjct: 64 GDVTVESDVINLVQSAIKEFGKLDVMINNAGLENPVSSHEMSLSDWNKVIDTNLTGAFLG 123 Query: 111 FQQTMNQFRRQR-GGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 ++ + F G ++ ++S P Y ASK +K + ++ LE A G+R Sbjct: 124 SREAIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRV 183 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N + PG+ +T + + + + IP+G I P+EIA +LAS Sbjct: 184 NNIGPGAINTPINAEKFADPEQR--------ADVESMIPMGYIGEPEEIAAVAAWLASSE 235 Query: 230 ASHITLQDIVVDGGSTL 246 AS++T + DGG TL Sbjct: 236 ASYVTGITLFADGGMTL 252 >1UZM-A nrPDB Length = 247 Score = 229 bits (584), Expect = 9e-61, Method: Composition-based stats. Identities = 72/245 (29%), Positives = 116/245 (47%), Gaps = 11/245 (4%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQV 62 F ++V VTG +GIG A A G KV + + F EV DV D+ V + Sbjct: 13 FVSRSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPKGLFGVEV-DVTDSDAVDRA 71 Query: 63 CQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQR 122 + ++ LV+ AG+ ++++E +++ N+ GAF + Q+ +R + Sbjct: 72 FTAVEEHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNK 131 Query: 123 GGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQ 182 G ++ + S + + Y ASKA + +A S+ EL+ + V NVV+PG DTDM Sbjct: 132 FGRMIFIGSVSGLWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAPGYIDTDMT 191 Query: 183 RTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDG 242 R L + IP ++ P E+A + FLAS+ AS+I+ I VDG Sbjct: 192 RALDER----------IQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISGAVIPVDG 241 Query: 243 GSTLG 247 G +G Sbjct: 242 GMGMG 246 >6NRP-A nrPDB Length = 263 Score = 228 bits (583), Expect = 1e-60, Method: Composition-based stats. Identities = 70/251 (27%), Positives = 116/251 (46%), Gaps = 25/251 (9%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV-----------MDVA 54 + + VTG+ +GIG A AL +AG VT ++ E E+ DV Sbjct: 25 RRILVTGSSRGIGKAIALQLAKAGFDVTVHARSRQAEAEQVVQEIQALGQNSHYLMFDVN 84 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQ-Q 113 + V Q+ ++ + + +V AG+ GA L+ +DW + + ++ G +N+ + Sbjct: 85 ERQTVQQILEQDVEQHGGFYGVVLNAGLTHDGAFPALTDQDWDEVISTSLDGFYNVLKPL 144 Query: 114 TMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 M ++GG IVT++S + G Y A+KA L ++ LELA + N V+ Sbjct: 145 IMPMIHLRKGGRIVTLSSVSGIMGNRGQVNYSAAKAGLIGATKALALELAKRKITVNCVA 204 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 PG +T+M E IPL ++ + E+A+ + FL SD AS++ Sbjct: 205 PGLIETEMVT-------------DEVKEHALKMIPLQRMGQVDEVASVVKFLCSDEASYV 251 Query: 234 TLQDIVVDGGS 244 T Q I V+GG Sbjct: 252 TRQVISVNGGL 262 >3AUT-A nrPDB Length = 269 Score = 227 bits (580), Expect = 3e-60, Method: Composition-based stats. Identities = 69/256 (26%), Positives = 110/256 (42%), Gaps = 20/256 (7%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV----------- 50 D K V +TG G+G A A+ F + AKV +E EV Sbjct: 12 DLKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQAIIVQ 71 Query: 51 MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 DV V + Q + E LD ++N AG+ + +LS ++W + N+ GAF Sbjct: 72 GDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGAFLG 131 Query: 111 FQQTMNQFRRQR-GGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 ++ + F G ++ ++S P Y ASK +K + ++ LE A G+R Sbjct: 132 SREAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRV 191 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N + PG+ +T + + + IP+G I +P+E+A FLAS Sbjct: 192 NNIGPGAMNTPINAEKFADPVQR--------ADVESMIPMGYIGKPEEVAAVAAFLASSQ 243 Query: 230 ASHITLQDIVVDGGST 245 AS++T + DGG T Sbjct: 244 ASYVTGITLFADGGMT 259 >2ZAT-A nrPDB Length = 260 Score = 227 bits (580), Expect = 3e-60, Method: Composition-based stats. Identities = 62/252 (24%), Positives = 107/252 (42%), Gaps = 19/252 (7%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQ----------AFTQEQYPFATEVMD 52 K VT + GIG A A + GA V + E V Sbjct: 12 LENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTVCH 71 Query: 53 VADAAQVAQVCQRLLAETERLDALVNAAGILRM-GATDQLSKEDWQQTFAVNVGGAFNLF 111 V A ++ + +D LV+ A + G ++E W + VNV + Sbjct: 72 VGKAEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKATVLMT 131 Query: 112 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 171 + + + ++ GG+++ V+S A+ P + Y SK AL L ++ +ELA +R N Sbjct: 132 KAVVPEMEKRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIRVNC 191 Query: 172 VSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLAS 231 ++PG T+ + LW+ + E K + + ++ P++ A + FL S+ AS Sbjct: 192 LAPGLIKTNFSQVLWMD--------KARKEYMKESLRIRRLGNPEDCAGIVSFLCSEDAS 243 Query: 232 HITLQDIVVDGG 243 +IT + +VV GG Sbjct: 244 YITGETVVVGGG 255 >2AE2-A nrPDB Length = 260 Score = 227 bits (579), Expect = 3e-60, Method: Composition-based stats. Identities = 58/254 (22%), Positives = 101/254 (39%), Gaps = 16/254 (6%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQ----------EQYPFATEVM 51 + G VTG +GIGY GA V + + + + V Sbjct: 6 NLEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKVEASVC 65 Query: 52 DVADAAQVAQVCQRLLAET-ERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 D++ ++ ++ + +L+ LVN AGI+ + ED+ ++N A++L Sbjct: 66 DLSSRSERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINFEAAYHL 125 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 + G +V ++S + + YGA+K A+ L + E A +R N Sbjct: 126 SVLAHPFLKASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAFEWAKDNIRVN 185 Query: 171 VVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 230 V PG T + + +E + L ++ P+E+A + FL A Sbjct: 186 GVGPGVIATSLVEMTIQDPEQKEN-----LNKLIDRCALRRMGEPKELAAMVAFLCFPAA 240 Query: 231 SHITLQDIVVDGGS 244 S++T Q I VDGG Sbjct: 241 SYVTGQIIYVDGGL 254 >1GEG-A nrPDB Length = 256 Score = 227 bits (579), Expect = 4e-60, Method: Composition-based stats. Identities = 68/252 (26%), Positives = 112/252 (44%), Gaps = 12/252 (4%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFD----------QAFTQEQYPFATEVMDVAD 55 K VTGAG+GIG A AL V+ G V D Q +DV+D Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDVSD 62 Query: 56 AAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTM 115 QV ++ D +VN AG+ + ++ E + + +NV G Q + Sbjct: 63 RDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWGIQAAV 122 Query: 116 NQFRR-QRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSP 174 F++ GG I+ S A H ++ Y +SK A++ L + +LA G+ N P Sbjct: 123 EAFKKEGHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGITVNGYCP 182 Query: 175 GSTDTDMQRTLWVSDDAEEQRIRGFG-EQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 G T M + + G+G +F I LG+++ P+++A + +LAS + ++ Sbjct: 183 GIVKTPMWAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAACVSYLASPDSDYM 242 Query: 234 TLQDIVVDGGST 245 T Q +++DGG Sbjct: 243 TGQSLLIDGGMV 254 >5U9P-A nrPDB Length = 265 Score = 226 bits (578), Expect = 4e-60, Method: Composition-based stats. Identities = 70/254 (27%), Positives = 109/254 (42%), Gaps = 18/254 (7%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQ----------EQYPFATEVM 51 G+ +TG+G+GIG A EAGA + D+ + E + V Sbjct: 17 RLDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARRFRDEGFAADHAVF 76 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 DVA+ AQV A +D LVN AGI R D +DW VN+ G FN+ Sbjct: 77 DVAEHAQVRAAIDEFEARVGAIDILVNNAGIQRRAPLDAFEPDDWHALMRVNLDGVFNVA 136 Query: 112 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 171 Q + G I+ + S + R ++ Y A+K A++ L + + A G++ N Sbjct: 137 QAVARHMIARGHGKIINICSVQSELARPTIAPYAATKGAVRMLTKGMCADWARYGIQANG 196 Query: 172 VSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLAS 231 ++PG +T++ R L F + P G+ + E+ +FLAS + Sbjct: 197 LAPGYFETELNRALVDDA--------AFSDWLCKRTPAGRWGQVDELCGAAIFLASAASD 248 Query: 232 HITLQDIVVDGGST 245 + Q + VDGG T Sbjct: 249 FVNGQTLFVDGGLT 262 >3VZS-A nrPDB Length = 257 Score = 226 bits (577), Expect = 6e-60, Method: Composition-based stats. Identities = 61/253 (24%), Positives = 110/253 (43%), Gaps = 21/253 (8%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTG-----------FDQAFTQEQYPFATEVMDVA 54 + +VTG GIG A + G +V + + + F +VA Sbjct: 15 RIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGNVA 74 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 D ++ +E +D L+N AGI R ++++ DW N+ FN+ +Q Sbjct: 75 DWDSTKTAFDKVKSEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNVTKQV 134 Query: 115 MNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSP 174 ++ + G IV ++S + G + Y +KA L +++ E+A GV N VSP Sbjct: 135 IDGMADRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNTVSP 194 Query: 175 GSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHIT 234 G TDM + + + ++ IP+ ++ P+EIA+ +L+S+ + T Sbjct: 195 GYIATDMVKAIR----------QDVLDKIVATIPVKRLGLPEEIASICAWLSSEESGFST 244 Query: 235 LQDIVVDGGSTLG 247 D ++GG +G Sbjct: 245 GADFSLNGGLHMG 257 >5VT6-A nrPDB Length = 269 Score = 225 bits (575), Expect = 1e-59, Method: Composition-based stats. Identities = 66/254 (25%), Positives = 109/254 (42%), Gaps = 20/254 (7%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQ-----------EQYPFATEVMD 52 + + +VTG G+G A + +AG V F +D Sbjct: 24 AKRVAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWLMHERDAGRDFKAYAVD 83 Query: 53 VADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQ 112 VAD + +++LA+ ++D L+N AGI R +++K DW ++ FN+ + Sbjct: 84 VADFESCERCAEKVLADFGKVDVLINNAGITRDATFMKMTKGDWDAVMRTDLDAMFNVTK 143 Query: 113 QTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVV 172 Q + +R G IV + S G + Y ++KA + ++ LE A G+ N V Sbjct: 144 QFIAGMVERRFGRIVNIGSVNGSRGAFGQANYASAKAGIHGFTKTLALETAKRGITVNTV 203 Query: 173 SPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASH 232 SPG T M + + IP+G++ RP E+A I FL SD A Sbjct: 204 SPGYLATAMVEAVPQ---------DVLEAKILPQIPVGRLGRPDEVAALIAFLCSDDAGF 254 Query: 233 ITLQDIVVDGGSTL 246 +T D+ ++GG + Sbjct: 255 VTGADLAINGGMHM 268 >5OJG-A nrPDB Length = 260 Score = 225 bits (573), Expect = 2e-59, Method: Composition-based stats. Identities = 76/254 (29%), Positives = 122/254 (48%), Gaps = 17/254 (6%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTG-------FDQAFTQEQYPFATEVMDVA 54 F GK VT A KGIG A A ++ GA V D+A + T+V +A Sbjct: 7 RFEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIA 66 Query: 55 ----DAAQVAQVCQRLLAETERLDALVNAAGILR-MGATDQLSKEDWQQTFAVNVGGAFN 109 ++ L + +++ LVN GI G ++S + W + F VNV F Sbjct: 67 GHIASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVKAGFQ 126 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 + + ++ GGAI+ AS +A+ G++AYG +K L L ++ + LA +R Sbjct: 127 MTKLVHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRV 186 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N ++PG T M + LW + E+ + E I LG++ P + A T+ +LASD Sbjct: 187 NGIAPGVIKTKMSQVLWDGGEDAEKELTDIQE-----IALGRLGVPDDCAGTVAYLASDD 241 Query: 230 ASHITLQDIVVDGG 243 +S+IT + I++ GG Sbjct: 242 SSYITGEMIIIAGG 255 >2CDH-G nrPDB Length = 244 Score = 224 bits (571), Expect = 3e-59, Method: Composition-based stats. Identities = 71/249 (28%), Positives = 109/249 (43%), Gaps = 22/249 (8%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV-----------MDVAD 55 V VTGA +GIG A AL+ +AG KV + + ++ DV+ Sbjct: 3 VVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKAAEEVSKQIEAYGGQAITFGGDVSK 62 Query: 56 AAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTM 115 A V + + + +D +VN AGI R ++ K W + +N+ G F Q Sbjct: 63 EADVEAMMKTAIDAWGTIDVVVNNAGITRDTLLIRMKKSQWDEVIDLNLTGVFLCTQAAT 122 Query: 116 NQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPG 175 ++R G I+ +AS IG + Y A+KA + + + E A + NVV PG Sbjct: 123 KIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNINVNVVCPG 182 Query: 176 STDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLA-SDLASHIT 234 +DM L ++ IPLG+ +P+ +A + FLA S AS+IT Sbjct: 183 FIASDMTAKLG----------EDMEKKILGTIPLGRTGQPENVAGLVEFLALSPAASYIT 232 Query: 235 LQDIVVDGG 243 Q +DGG Sbjct: 233 GQAFTIDGG 241 >4Z9Y-A nrPDB Length = 253 Score = 224 bits (571), Expect = 3e-59, Method: Composition-based stats. Identities = 67/252 (26%), Positives = 120/252 (47%), Gaps = 17/252 (6%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD--------QAFTQEQYPFATEVMDV 53 D GK +TG G+G A+ +AG + G + + T F + D+ Sbjct: 7 DLQGKVALITGCDTGLGQGMAIGLAQAGCDIVGVNIVEPKDTIEKVTALGRRFLSLTADM 66 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 ++ + A++ ++ +AE +D LVN AGI+R + S+++W +N+ F + Q Sbjct: 67 SNVSGHAELVEKAVAEFGHVDILVNNAGIIRREDAIEFSEKNWDDVMNLNIKSVFFMSQT 126 Query: 114 TMNQFRRQ-RGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVV 172 QF +Q +GG I+ +AS + I + +Y ASK+A+ + + E A G+ N + Sbjct: 127 VARQFIKQGKGGKIINIASMLSFQGGIRVPSYTASKSAVMGVTRLMANEWAKHGINVNAI 186 Query: 173 SPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASH 232 +PG T+ + L ++ ++ + IP G+ PQ++ +FLAS + + Sbjct: 187 APGYMATNNTQQLRADEERSKEILD--------RIPAGRWGLPQDLMGPSVFLASSASDY 238 Query: 233 ITLQDIVVDGGS 244 I I VDGG Sbjct: 239 INGYTIAVDGGW 250 >1YXM-A nrPDB Length = 303 Score = 224 bits (571), Expect = 3e-59, Method: Composition-based stats. Identities = 63/259 (24%), Positives = 109/259 (42%), Gaps = 22/259 (8%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQ---------------EQYPFA 47 G+ VTG GIG A +E G+ V + + +Q Sbjct: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 Query: 48 TEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGA 107 ++ + +V + + L +++ LVN G + + +S + W N+ G Sbjct: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 Query: 108 FNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGV 167 F + + + + ++ GG+IV + GA++A + +L S+ LE A SG+ Sbjct: 136 FYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 Query: 168 RCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLAS 227 R N V+PG + + S + F E IP +I P+E+++ + FL S Sbjct: 195 RINCVAPGVIYSQTAVENYGSWG------QSFFEGSFQKIPAKRIGVPEEVSSVVCFLLS 248 Query: 228 DLASHITLQDIVVDGGSTL 246 AS IT Q + VDGG +L Sbjct: 249 PAASFITGQSVDVDGGRSL 267 >4RZI-B nrPDB Length = 240 Score = 222 bits (567), Expect = 8e-59, Method: Composition-based stats. Identities = 64/243 (26%), Positives = 105/243 (43%), Gaps = 11/243 (4%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVA 60 + K + VTG +GIG A E GAKV D A V +V D + Sbjct: 4 LGLEDKVIVVTGGNRGIGAAIVKLLQEMGAKVAFTDLATDGGNTEALGVVANVTDLESMT 63 Query: 61 QVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRR 120 + + + +V AGI + +L+ DW VN+ G + + Sbjct: 64 AAAAEITDKLGPVYGVVANAGITKDNFFPKLTPADWDAVLNVNLKGVAYSIKPFIEGMYE 123 Query: 121 QRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTD 180 ++ G+IV ++S + +G + Y A+KA + + S+ E A GVR N V+PG DT+ Sbjct: 124 RKAGSIVAISSISGERGNVGQTNYSATKAGVIGMMKSLAREGARYGVRANAVAPGFIDTE 183 Query: 181 MQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASD-LASHITLQDIV 239 M + E+ IP + +P+EIA + FL S +S++T + + Sbjct: 184 MTLAIR----------EDIREKITKEIPFRRFGKPEEIAWAVAFLLSPVASSYVTGEVLR 233 Query: 240 VDG 242 V+G Sbjct: 234 VNG 236 >2Q2Q-A nrPDB Length = 255 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 65/251 (25%), Positives = 99/251 (39%), Gaps = 9/251 (3%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD--------QAFTQEQYPFATEVMDVA 54 GK VTG+ GIG A AGA + + D++ Sbjct: 2 LKGKTALVTGSTSGIGLGIAQVLARAGANIVLNGFGDPAPALAEIARHGVKAVHHPADLS 61 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 D AQ+ + E +D LVN AGI + +Q E W + A+N+ F+ + Sbjct: 62 DVAQIEALFALAEREFGGVDILVNNAGIQHVAPVEQFPLESWDKIIALNLSAVFHGTRLA 121 Query: 115 MNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSP 174 + R + G I+ +AS G +AY A+K + L VGLE A S V CN + P Sbjct: 122 LPGMRARNWGRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGLETATSNVTCNAICP 181 Query: 175 GSTDTDM-QRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 G T + Q+ + ++ + P P+ + +LFL S+ S + Sbjct: 182 GWVLTPLVQKQIDDRAANGGDPLQAQHDLLAEKQPSLAFVTPEHLGELVLFLCSEAGSQV 241 Query: 234 TLQDIVVDGGS 244 VDGG Sbjct: 242 RGAAWNVDGGW 252 >3V2H-A nrPDB Length = 281 Score = 220 bits (560), Expect = 7e-58, Method: Composition-based stats. Identities = 68/255 (26%), Positives = 109/255 (42%), Gaps = 16/255 (6%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVM------------DV 53 K +TG+ GIG A A +AGA + E EV D+ Sbjct: 26 KTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAGLSSGTVLHHPADM 85 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 +++A + + D LVN AG+ + + E W + AVN+ +F+ + Sbjct: 86 TKPSEIADMMAMVADRFGGADILVNNAGVQFVEKIEDFPVEQWDRIIAVNLSSSFHTIRG 145 Query: 114 TMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 + +++ G I+ +AS SAY A+K + L +V LE+A SGV N + Sbjct: 146 AIPPMKKKGWGRIINIASAHGLVASPFKSAYVAAKHGIMGLTKTVALEVAESGVTVNSIC 205 Query: 174 PGSTDTDMQRTLWVSDDAEEQRI---RGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 230 PG T + + D A + I + E G P K +++A+ L+LA D A Sbjct: 206 PGYVLTPLVEK-QIPDQARTRGITEEQVINEVMLKGQPTKKFITVEQVASLALYLAGDDA 264 Query: 231 SHITLQDIVVDGGST 245 + IT + +DGG T Sbjct: 265 AQITGTHVSMDGGWT 279 >1NFF-A nrPDB Length = 260 Score = 219 bits (559), Expect = 8e-58, Method: Composition-based stats. Identities = 71/253 (28%), Positives = 111/253 (43%), Gaps = 22/253 (8%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV-------MDVA 54 +GK V+G +G+G + A V GAKV D + + A +DV Sbjct: 4 RLTGKVALVSGGARGMGASHVRAMVAEGAKVVFGDILDEEGKAMAAELADAARYVHLDVT 63 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 AQ + L LVN AGIL +G + + +WQ+ VN+ G F + Sbjct: 64 QPAQWKAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLTGVFLGIRAV 123 Query: 115 MNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSP 174 + + G+I+ ++S + Y A+K A++ L S LEL SG+R N + P Sbjct: 124 VKPMKEAGRGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTALELGPSGIRVNSIHP 183 Query: 175 GSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHIT 234 G T M + + LG+ A P E++N +++LASD +S+ T Sbjct: 184 GLVKTPMT---------------DWVPEDIFQTALGRAAEPVEVSNLVVYLASDESSYST 228 Query: 235 LQDIVVDGGSTLG 247 + VVDGG+ G Sbjct: 229 GAEFVVDGGTVAG 241 >3W8F-A nrPDB Length = 260 Score = 218 bits (556), Expect = 2e-57, Method: Composition-based stats. Identities = 63/257 (24%), Positives = 99/257 (38%), Gaps = 14/257 (5%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV------------ 50 GK VTG+ GIG A A +AGA V ++ + + Sbjct: 2 LKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVKAYYLN 61 Query: 51 MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 D++DA + LD LVN AGI ++ + W A+N+ F+ Sbjct: 62 ADLSDAQATRDFIAKAAEALGGLDILVNNAGIQHTAPIEEFPVDKWNAIIALNLSAVFHG 121 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 + ++Q G I+ +AS + SAY A+K + L LE AG G+ CN Sbjct: 122 TAAALPIMQKQGWGRIINIASAHGLVASVNKSAYVAAKHGVVGLTKVTALENAGKGITCN 181 Query: 171 VVSPGSTDTDMQRTL--WVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASD 228 + PG T + +S E P + P+++ +FL+S Sbjct: 182 AICPGWVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQPSLQFVTPEQLGGAAVFLSSA 241 Query: 229 LASHITLQDIVVDGGST 245 A +T + +DGG T Sbjct: 242 AADQMTGTTLSLDGGWT 258 >6CI9-A nrPDB Length = 259 Score = 218 bits (556), Expect = 2e-57, Method: Composition-based stats. Identities = 69/256 (26%), Positives = 102/256 (39%), Gaps = 21/256 (8%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQE----------QYPFATEVM 51 G++ VTG KGIG A F AG V + + Sbjct: 6 SLEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVRA 65 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 DV D + ++ LD + AGI G + L+ +D +Q VN G + Sbjct: 66 DVTDPEDARRTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKGTVYIV 125 Query: 112 QQTMNQFRRQRGGAIVTVASDAA-HTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 Q + G +V +S T G S YGASKAA + +ELA + N Sbjct: 126 QAALQALTASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAMELAPKKITIN 185 Query: 171 VVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 230 V PG+ T+ + + + +Q IP G++ +I N LF A+D A Sbjct: 186 AVLPGNIMTEGLDEMG----------QDYLDQMASAIPAGRLGSVADIGNAALFFATDEA 235 Query: 231 SHITLQDIVVDGGSTL 246 +++T Q +VVDGG L Sbjct: 236 AYVTGQTLVVDGGQVL 251 >1X1T-A nrPDB Length = 260 Score = 218 bits (555), Expect = 2e-57, Method: Composition-based stats. Identities = 67/257 (26%), Positives = 101/257 (39%), Gaps = 14/257 (5%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVT--GFDQAFTQEQYPFATEV---------- 50 GK VTG+ GIG A A GA + GF A E+ Sbjct: 2 LKGKVAVVTGSTSGIGLGIATALAAQGADIVLNGFGDAAEIEKVRAGLAAQHGVKVLYDG 61 Query: 51 MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 D++ V + + + R+D LVN AGI + E W A+N+ F+ Sbjct: 62 ADLSKGEAVRGLVDNAVRQMGRIDILVNNAGIQHTALIEDFPTEKWDAILALNLSAVFHG 121 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 + ++Q G I+ +AS SAY A+K + LE AG G+ N Sbjct: 122 TAAALPHMKKQGFGRIINIASAHGLVASANKSAYVAAKHGVVGFTKVTALETAGQGITAN 181 Query: 171 VVSPGSTDTDMQRT--LWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASD 228 + PG T + +++ + E P + P+++ T +FLASD Sbjct: 182 AICPGWVRTPLVEKQISALAEKNGVDQETAARELLSEKQPSLQFVTPEQLGGTAVFLASD 241 Query: 229 LASHITLQDIVVDGGST 245 A+ IT + VDGG T Sbjct: 242 AAAQITGTTVSVDGGWT 258 >4CQL-A nrPDB Length = 261 Score = 216 bits (552), Expect = 5e-57, Method: Composition-based stats. Identities = 70/258 (27%), Positives = 114/258 (44%), Gaps = 29/258 (11%) Query: 8 VWVTGAGKGIGYATALAFVEAGAKVTG--FDQAFTQEQYPF---------------ATEV 50 VTGAG GIG A ++ GA V D+A QE A Sbjct: 14 ALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQ 73 Query: 51 MDVADAAQVAQVCQRLLAETERL-DALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 DV++A + +++ A R +V+ AGI + +S++DW + AVN+ G F Sbjct: 74 ADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFL 133 Query: 110 LFQQTMNQFRRQR-GGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVR 168 + Q G+I+ ++S +G + Y ASKA + L + EL G+R Sbjct: 134 VTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIR 193 Query: 169 CNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASD 228 CN V PG T M + + + ++ IP+G + P+++A+ + FLAS+ Sbjct: 194 CNSVLPGFIATPMTQKV----------PQKVVDKITEMIPMGHLGDPEDVADVVAFLASE 243 Query: 229 LASHITLQDIVVDGGSTL 246 + +IT + V GG + Sbjct: 244 DSGYITGTSVEVTGGLFM 261 >4CQM-B nrPDB Length = 244 Score = 216 bits (552), Expect = 6e-57, Method: Composition-based stats. Identities = 73/248 (29%), Positives = 103/248 (41%), Gaps = 22/248 (8%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATE-------VMDVADAAQ 58 K V G +GIG A A G ++ + + DVA Sbjct: 10 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHD 69 Query: 59 VAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQF 118 V + L R++ LVNAAGI R G + ED N+ G+ + M Sbjct: 70 VQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 129 Query: 119 RRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTD 178 +Q+GG+IV V S G S Y ASK L + ++ E+A +R NVV+PG Sbjct: 130 IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH 189 Query: 179 TDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDI 238 TDM + L E K IPLG+ E+A+ ++FL + +IT + Sbjct: 190 TDMTKDLK-------------EEHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVL 234 Query: 239 VVDGGSTL 246 VVDGG L Sbjct: 235 VVDGGLQL 242 >1K2W-A nrPDB Length = 256 Score = 216 bits (551), Expect = 6e-57, Method: Composition-based stats. Identities = 78/255 (30%), Positives = 121/255 (47%), Gaps = 9/255 (3%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD------QAFTQEQYPFATEV-MDV 53 M GK +TG+ +GIG A A A+V GA+V D +A E P A + +DV Sbjct: 1 MRLDGKTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAAEIGPAACAIALDV 60 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 D A + + LL +D LVN A + + ++++E + + FA+NV G + Q Sbjct: 61 TDQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGTLFMMQA 120 Query: 114 TMNQFRR-QRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVV 172 RGG I+ +AS A + Y A+KAA+ SL S GL L G+ N + Sbjct: 121 VARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNLIRHGINVNAI 180 Query: 173 SPGSTDTDMQRTLWVSDDAEEQRIRGFGE-QFKLGIPLGKIARPQEIANTILFLASDLAS 231 +PG D + + E RG + Q +P G++ R +++ +FLA+ A Sbjct: 181 APGVVDGEHWDGVDAKFADYENLPRGEKKRQVGAAVPFGRMGRAEDLTGMAIFLATPEAD 240 Query: 232 HITLQDIVVDGGSTL 246 +I Q VDGG+ + Sbjct: 241 YIVAQTYNVDGGNWM 255 >3UVE-A nrPDB Length = 286 Score = 215 bits (548), Expect = 2e-56, Method: Composition-based stats. Identities = 67/279 (24%), Positives = 104/279 (37%), Gaps = 39/279 (13%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQY------------------- 44 GK +VTGA +G G + A+ + GA + D Sbjct: 10 EGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDLAETAD 69 Query: 45 -------PFATEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMG-ATDQLSKEDW 96 T +DV D + + + RLD +V AGI G D+ S+EDW Sbjct: 70 LVKGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNGGDTLDKTSEEDW 129 Query: 97 QQTFAVNVGGAFNLFQQTMNQFRRQ-RGGAIVTVASDAAHTPRIGMSAYGASKAALKSLA 155 + +N+ G + + + RGG+I+ +S Y A+K + L Sbjct: 130 TEMIDINLAGVWKTVKAGVPHMIAGGRGGSIILTSSVGGLKAYPHTGHYVAAKHGVVGLM 189 Query: 156 LSVGLELAGSGVRCNVVSPGSTDTDMQRT-------LWVSDDAEEQRIRGFGEQFKL-GI 207 + G+EL +R N V P T M ++ + + F I Sbjct: 190 RAFGVELGQHMIRVNSVHPTHVKTPMLHNEGTFKMFRPDLENPGPDDMAPICQMFHTLPI 249 Query: 208 PLGKIARPQEIANTILFLASDLASHITLQDIVVDGGSTL 246 P P +I+N +LF ASD A +IT + +D GS L Sbjct: 250 P---WVEPIDISNAVLFFASDEARYITGVTLPIDAGSCL 285 >3WTC-A nrPDB Length = 262 Score = 213 bits (543), Expect = 5e-56, Method: Composition-based stats. Identities = 71/257 (27%), Positives = 112/257 (43%), Gaps = 12/257 (4%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD----------QAFTQEQYPFATEV 50 M SGK VTGA +GIG A AL + GA V D + Sbjct: 4 MSLSGKIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEALGRRAVALT 63 Query: 51 MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 D+++ Q LD +VN AGI ++ + + ++ F++NV G Sbjct: 64 ADISNRDQFRSTLADAAKTLGGLDIMVNNAGICQVKPILDIEPAEIEKIFSINVQGVLWG 123 Query: 111 FQQTMNQFRRQR-GGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 Q F+ + G I+ S A H + AY A+K A+++L S ELA SG+ Sbjct: 124 MQAAATLFKEKGTKGKIINACSIAGHEGYPLLGAYSATKFAVRALTQSAAKELASSGITV 183 Query: 170 NVVSPGSTDTDMQRTLWVSD-DAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASD 228 N PG TDM T+ + I +++ GI LG++ ++A + +L+S Sbjct: 184 NSYCPGIVGTDMWVTIDKRMAEITGTEIGATYKKYVEGIALGRVETADDVAGFVAYLSSS 243 Query: 229 LASHITLQDIVVDGGST 245 A ++T Q +++DGG Sbjct: 244 DADYMTGQSVLIDGGLV 260 >5T5Q-A nrPDB Length = 247 Score = 213 bits (543), Expect = 5e-56, Method: Composition-based stats. Identities = 73/255 (28%), Positives = 117/255 (45%), Gaps = 22/255 (8%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQ---------YPFATEVMD 52 +F + + +TGA GIG A A F +GA + D AT D Sbjct: 6 EFENRTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSPERIATIKAD 65 Query: 53 VADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQ 112 + A + + +D LV +AGI + ++S DW +T ++N+ G F L + Sbjct: 66 ASSADDAEKTVALAMERFGGIDFLVPSAGIYQAKPFAEMSDADWHRTISINLDGVFYLCK 125 Query: 113 QTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVV 172 + + + +IVT+AS AA+ + YGA+K A+ S+ ++ ELA R N V Sbjct: 126 RALPALKEDS--SIVTLASLAAYRGAYVNAHYGATKGAMVSMTRALSRELAPK-TRVNGV 182 Query: 173 SPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASH 232 SPG +T M L ++ ++ PL ++ +P EIA+ I FL S AS Sbjct: 183 SPGIIETPMTSEL----------LKTRMDETMTQTPLKRLGKPSEIASVIAFLCSPAASF 232 Query: 233 ITLQDIVVDGGSTLG 247 +T + I V+GG + Sbjct: 233 VTGETIQVNGGIYMA 247 >3WYE-A nrPDB Length = 256 Score = 213 bits (543), Expect = 6e-56, Method: Composition-based stats. Identities = 78/256 (30%), Positives = 121/256 (47%), Gaps = 20/256 (7%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFD----------QAFTQEQYPFATEVMDVAD 55 K VTGAG+GIG A AL V+ G V D Q +DV+D Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDVSD 62 Query: 56 AAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTM 115 QV ++ D +VN AGI ++ ++++ED +Q ++VNV F Q + Sbjct: 63 RDQVFAAVEQARKTLGGFDVIVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQAAV 122 Query: 116 NQFRR-QRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSP 174 F++ GG I+ AS AA +SAY +K A++ L + +LA G+ N P Sbjct: 123 EAFKKEGHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAARDLAPLGITVNGYCP 182 Query: 175 GSTDTDMQRTLWVSDDAEEQRIRGFG-----EQFKLGIPLGKIARPQEIANTILFLASDL 229 G T M W DAE +I G +++ I LG+ + P+++A + FLAS Sbjct: 183 GIVGTGM----WEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLASPD 238 Query: 230 ASHITLQDIVVDGGST 245 + ++T Q +++DGG Sbjct: 239 SDYMTGQSLLIDGGMV 254 >1O5I-A nrPDB Length = 249 Score = 212 bits (541), Expect = 1e-55, Method: Composition-based stats. Identities = 64/241 (26%), Positives = 114/241 (47%), Gaps = 16/241 (6%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFA-TEVMDVADAAQVAQVCQ 64 K V V A +GIG A A + GA+VT + + V D+ + Sbjct: 20 KGVLVLAASRGIGRAVADVLSQEGAEVTICARNEELLKRSGHRYVVCDLRKDLDL----- 74 Query: 65 RLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGG 124 L + + +D LV AG + G D+L+ ED+++ + + + + + G Sbjct: 75 -LFEKVKEVDILVLNAGGPKAGFFDELTNEDFKEAIDSLFLNMIKIVRNYLPAMKEKGWG 133 Query: 125 AIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQRT 184 IV + S + +P + +++ AL ++ E+A G+ N V+PG T+T+ + Sbjct: 134 RIVAITSFSVISPIENLYTSNSARMALTGFLKTLSFEVAPYGITVNCVAPGWTETERVKE 193 Query: 185 LWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDGGS 244 L + + Q + IP+ ++A+P+EIA+ + FL S+ AS++T Q IVVDGG Sbjct: 194 LLSEEKKK---------QVESQIPMRRMAKPEEIASVVAFLCSEKASYLTGQTIVVDGGL 244 Query: 245 T 245 + Sbjct: 245 S 245 >4IS3-A nrPDB Length = 268 Score = 211 bits (539), Expect = 2e-55, Method: Composition-based stats. Identities = 75/257 (29%), Positives = 116/257 (45%), Gaps = 23/257 (8%) Query: 1 MDF-SGKNVWVTGAGKGIGYATALAFVEAGAKVTGF-------DQAFTQEQYPFATEVM- 51 M+ K +TG +GIG+A A F++ GAKV+ F D A Q + + E + Sbjct: 20 MNLVQDKVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYPEEEVL 79 Query: 52 ----DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGA 107 D+ V ++ + RLD ++N AGI ++S+E+++ +NV G Sbjct: 80 GFAPDLTSRDAVMAAVGQVAQKYGRLDVMINNAGITSNNVFSRVSEEEFKHIMDINVTGV 139 Query: 108 FNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGV 167 FN + + G I+ AS + Y ASKA++ L +G E+ + Sbjct: 140 FNGAWCAYQCMKDAKKGVIINTASVTGIFGSLSGVGYPASKASVIGLTHGLGREIIRKNI 199 Query: 168 RCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLAS 227 R V+PG +TDM E + +P+ ++ P+EIAN LFLAS Sbjct: 200 RVVGVAPGVVNTDMTNG----------NPPEIMEGYLKALPMKRMLEPEEIANVYLFLAS 249 Query: 228 DLASHITLQDIVVDGGS 244 DLAS IT + VDG Sbjct: 250 DLASGITATTVSVDGAY 266 >3OIC-A nrPDB Length = 258 Score = 209 bits (533), Expect = 8e-55, Method: Composition-based stats. Identities = 64/254 (25%), Positives = 108/254 (42%), Gaps = 19/254 (7%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV-----------MD 52 K VTG+ +G+G A A+ E G + + A E+ + Sbjct: 3 QNKCALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALETAEEIEKLGVKVLVVKAN 62 Query: 53 VADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQ 112 V A++ ++ Q++ RLD VN A + +L + W T +N Q Sbjct: 63 VGQPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELEETHWDWTMNINAKALLFCAQ 122 Query: 113 QTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVV 172 + + GG IV+++S + + G SKAAL++L + +EL+ + N V Sbjct: 123 EAAKLMEKNGGGHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAVELSPKQIIVNAV 182 Query: 173 SPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASH 232 S G+ DTD + +D E + P G++ +++ +T+ FL S A Sbjct: 183 SGGAIDTDALKHFPNRED--------LLEDARQNTPAGRMVEIKDMVDTVEFLVSSKADM 234 Query: 233 ITLQDIVVDGGSTL 246 I Q I+VDGG +L Sbjct: 235 IRGQTIIVDGGRSL 248 >4DBZ-A nrPDB Length = 281 Score = 209 bits (533), Expect = 9e-55, Method: Composition-based stats. Identities = 63/251 (25%), Positives = 103/251 (41%), Gaps = 13/251 (5%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFT----------QEQYPFATEVMDVADA 56 VTGA GIG A + G +V + + DV Sbjct: 28 VALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGVEADGRTCDVRSV 87 Query: 57 AQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMN 116 ++ + ++ +D LVN AG GAT +L+ E W N+ G F + +Q + Sbjct: 88 PEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELADELWLDVVETNLTGVFRVTKQVLK 147 Query: 117 Q--FRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSP 174 + G IV +AS + + Y ASK + ++GLELA +G+ N V P Sbjct: 148 AGGMLERGTGRIVNIASTGGKQGLVHAAPYSASKHGVVGFTKALGLELARTGITVNAVCP 207 Query: 175 GSTDTDMQRTLWV-SDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 G +T M ++ D E ++ +P+G+ +P E+A + +L A+ + Sbjct: 208 GFVETPMAASVREHYSDIWEVSTEEAFDRITARVPIGRYVQPSEVAEMVAYLIGPGAAAV 267 Query: 234 TLQDIVVDGGS 244 T Q + V GG Sbjct: 268 TAQALNVCGGL 278 >4MOW-A nrPDB Length = 256 Score = 209 bits (532), Expect = 1e-54, Method: Composition-based stats. Identities = 68/255 (26%), Positives = 111/255 (43%), Gaps = 20/255 (7%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVT-----------GFDQAFTQEQYPFATEV 50 +GK VTGA KGIG A A A + GA V A T+ Sbjct: 11 KLAGKVAIVTGASKGIGAAIAKALADEGAAVVVNYASSKAGADAVVSAITEAGGRAVAVG 70 Query: 51 MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 DV+ AA ++ + RLD LVN +G+ + +++E +++ F NV G Sbjct: 71 GDVSKAADAQRIVDTAIETYGRLDVLVNNSGVYEFAPIEAITEEHYRRQFDTNVFGVLLT 130 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 Q + G +I+ ++S + Y +K A+ ++ + LEL +R N Sbjct: 131 TQAAVKHL--GEGASIINISSVVTSITPPASAVYSGTKGAVDAITGVLALELGPRKIRVN 188 Query: 171 VVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 230 ++PG T+ + + E ++ G PLG++ P +IA+ +FLASD A Sbjct: 189 AINPGMIVTEGTHSAGIIGSDLEAQVLG-------QTPLGRLGEPNDIASVAVFLASDDA 241 Query: 231 SHITLQDIVVDGGST 245 +T + +VV GG Sbjct: 242 RWMTGEHLVVSGGLN 256 >3RWB-A nrPDB Length = 247 Score = 208 bits (531), Expect = 1e-54, Method: Composition-based stats. Identities = 68/252 (26%), Positives = 108/252 (42%), Gaps = 17/252 (6%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQE-------QYPFATEVMDVA 54 +GK VTGA +GIG A A GA V D D++ Sbjct: 3 RLAGKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASIGKKARAIAADIS 62 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 D V + + A T +D LVN A I+ A D + + W++ VN+ G F + + Sbjct: 63 DPGSVKALFAEIQALTGGIDILVNNASIVPFVAWDDVDLDHWRKIIDVNLTGTFIVTRAG 122 Query: 115 MNQFR-RQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 +Q R + G ++++AS+ M+AY A+K + ++ EL + N V+ Sbjct: 123 TDQMRAAGKAGRVISIASNTFFAGTPNMAAYVAAKGGVIGFTRALATELGKYNITANAVT 182 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 PG ++D + + GF E + + +P+ IA+ + FLASD A I Sbjct: 183 PGLIESDGVKA------SPHNEAFGFVEMLQA---MKGKGQPEHIADVVSFLASDDARWI 233 Query: 234 TLQDIVVDGGST 245 T Q + VD G Sbjct: 234 TGQTLNVDAGMV 245 >4E6P-A nrPDB Length = 259 Score = 208 bits (530), Expect = 2e-54, Method: Composition-based stats. Identities = 73/254 (28%), Positives = 116/254 (45%), Gaps = 9/254 (3%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD-------QAFTQEQYPFATEVMDVA 54 GK+ +TG+ +GIG A A A+V GA V D QA + MDV Sbjct: 5 RLEGKSALITGSARGIGRAFAEAYVREGATVAIADIDIERARQAAAEIGPAAYAVQMDVT 64 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 + + LD LVN A + + ++++E +++ FA+NV G Q Sbjct: 65 RQDSIDAAIAATVEHAGGLDILVNNAALFDLAPIVEITRESYEKLFAINVAGTLFTLQAA 124 Query: 115 MNQFRRQ-RGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 Q Q RGG I+ +AS A ++ Y A+KAA+ SL S GL+L + N ++ Sbjct: 125 ARQMIAQGRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAGLDLIKHRINVNAIA 184 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFK-LGIPLGKIARPQEIANTILFLASDLASH 232 PG D + + E R RG ++ +P G++ +++ +FLAS + + Sbjct: 185 PGVVDGEHWDGVDALFARYENRPRGEKKRLVGEAVPFGRMGTAEDLTGMAIFLASAESDY 244 Query: 233 ITLQDIVVDGGSTL 246 I Q VDGG+ + Sbjct: 245 IVSQTYNVDGGNWM 258 >4IIV-A nrPDB Length = 267 Score = 208 bits (530), Expect = 2e-54, Method: Composition-based stats. Identities = 68/251 (27%), Positives = 111/251 (44%), Gaps = 23/251 (9%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTG---FDQAFTQEQYPFATE--------VMDVA 54 ++V VTGA KGIG A A G + D A QE DVA Sbjct: 27 RSVLVTGASKGIGRAIARQLAADGFNIGVHYHRDAAGAQETLNAIVANGGNGRLLSFDVA 86 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 + Q +V + +A+ +V+ AGI R A LS +DW N+ +N+ Q Sbjct: 87 NREQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPALSNDDWDAVIHTNLDSFYNVIQPC 146 Query: 115 -MNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 M ++GG I+T++S + G Y A+KA + ++ +ELA + N ++ Sbjct: 147 IMPMIGARQGGRIITLSSVSGVMGNRGQVNYSAAKAGIIGATKALAIELAKRKITVNCIA 206 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 PG DT M + ++ IP+ ++ + +E+A +L SD+A ++ Sbjct: 207 PGLIDTGMI-----------EMEESALKEAMSMIPMKRMGQAEEVAGLASYLMSDIAGYV 255 Query: 234 TLQDIVVDGGS 244 T Q I ++GG Sbjct: 256 TRQVISINGGM 266 >1AHH-A nrPDB Length = 255 Score = 208 bits (529), Expect = 2e-54, Method: Composition-based stats. Identities = 68/253 (26%), Positives = 117/253 (46%), Gaps = 20/253 (7%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQY----------PFATEV 50 + GK +TGAG GIG A+ F AGA V D + Sbjct: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 Query: 51 MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 D+ +++ + +++ ++D LVN AG D + D+++ + +NV F+L Sbjct: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFHL 125 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 Q + + GG I+T+ S AA I M++Y +SKAA L ++ +L +R N Sbjct: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 Query: 171 VVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 230 ++PG+ TD +++ + ++ P+ ++ +PQ+IAN LFL S A Sbjct: 186 GIAPGAILTDALKSVITPE---------IEQKMLQHTPIRRLGQPQDIANAALFLCSPAA 236 Query: 231 SHITLQDIVVDGG 243 S ++ Q + V GG Sbjct: 237 SWVSGQILTVSGG 249 >3V2G-A nrPDB Length = 271 Score = 207 bits (528), Expect = 3e-54, Method: Composition-based stats. Identities = 73/257 (28%), Positives = 106/257 (41%), Gaps = 25/257 (9%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV---------- 50 + +GK +VTG +GIG A A GA V + +E+ Sbjct: 27 ISLAGKTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQAGGRAVAI 86 Query: 51 -MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 D DA + Q + + LD LVN+AGI ++ + D+ + AVN F Sbjct: 87 RADNRDAEAIEQAIRETVEALGGLDILVNSAGIWHSAPLEETTVADFDEVMAVNFRAPFV 146 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAH-TPRIGMSAYGASKAALKSLALSVGLELAGSGVR 168 + GG I+T+ S+ A P G+S Y ASKAAL L + +L G+ Sbjct: 147 AIRSASRHL--GDGGRIITIGSNLAELVPWPGISLYSASKAALAGLTKGLARDLGPRGIT 204 Query: 169 CNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASD 228 N+V PGSTDTDM E + I G PQ+IA + +LA Sbjct: 205 VNIVHPGSTDTDMNPADG-----------DHAEAQRERIATGSYGEPQDIAGLVAWLAGP 253 Query: 229 LASHITLQDIVVDGGST 245 +T + +DGG+ Sbjct: 254 QGKFVTGASLTIDGGAN 270 >3T7C-A nrPDB Length = 299 Score = 207 bits (528), Expect = 3e-54, Method: Composition-based stats. Identities = 69/275 (25%), Positives = 106/275 (38%), Gaps = 35/275 (12%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD----------------------QAFTQ 41 GK ++TGA +G G + A+ GA + D + Sbjct: 27 EGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETVRQVEA 86 Query: 42 EQYPFATEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGA-TDQLSKEDWQQTF 100 +DV D + + + RLD ++ A + G +++ + W+ Sbjct: 87 LGRRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRMDPKTWRDMI 146 Query: 101 AVNVGGAFNLFQQTMNQFRRQ-RGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVG 159 VN+ GA+ + + RGG+IV +S + Y ASK L L ++ Sbjct: 147 DVNLNGAWITARVAIPHIMAGKRGGSIVFTSSIGGLRGAENIGNYIASKHGLHGLMRTMA 206 Query: 160 LELAGSGVRCNVVSPGSTDTDMQRT----LWVSDDAEEQRIRGFG----EQFKLGIPLGK 211 LEL +R N+V P S T M D E + F + L IP Sbjct: 207 LELGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFQVASRQMHVLPIP--- 263 Query: 212 IARPQEIANTILFLASDLASHITLQDIVVDGGSTL 246 P +I+N ILFL SD A +IT + VDGG+ L Sbjct: 264 YVEPADISNAILFLVSDDARYITGVSLPVDGGALL 298 >3D3W-A nrPDB Length = 244 Score = 206 bits (525), Expect = 7e-54, Method: Composition-based stats. Identities = 71/250 (28%), Positives = 107/250 (42%), Gaps = 19/250 (7%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQ------AFTQEQYPFATEVMDVADA 56 +G+ V VTGAGKGIG T A GA+V + + +E +D+ D Sbjct: 5 LAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDW 64 Query: 57 AQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMN 116 +R L +D LVN A + + +++KE + ++F VN+ + Q Sbjct: 65 EAT----ERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVAR 120 Query: 117 QFRRQR-GGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPG 175 + GAIV V+S + S Y ++K AL L + LEL +R N V+P Sbjct: 121 GLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPT 180 Query: 176 STDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITL 235 T M + W + + IPLGK A + + N ILFL SD + T Sbjct: 181 VVMTSMGQATWSDPHKAKTMLN--------RIPLGKFAEVEHVVNAILFLLSDRSGMTTG 232 Query: 236 QDIVVDGGST 245 + V+GG Sbjct: 233 STLPVEGGFW 242 >2CFC-A nrPDB Length = 250 Score = 206 bits (524), Expect = 9e-54, Method: Composition-based stats. Identities = 75/254 (29%), Positives = 109/254 (42%), Gaps = 22/254 (8%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATE-----------VMDVA 54 + VTGA G G A A F+ G +V D + + T DVA Sbjct: 3 RVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYADKVLRVRADVA 62 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGIL---RMGATDQLSKEDWQQTFAVNVGGAFNLF 111 D V + + +D LVN AGI G E + + AVNV G F Sbjct: 63 DEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVRGIFLGC 122 Query: 112 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 171 + + Q G IV +AS A+ G SAY SK A+ L SV ++ AGSG+RCN Sbjct: 123 RAVLPHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDYAGSGIRCNA 182 Query: 172 VSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLAS 231 V PG +T M + + +Q IP +I ++A+ ++FLA + A+ Sbjct: 183 VCPGMIETPMTQWRLDQPE--------LRDQVLARIPQKEIGTAAQVADAVMFLAGEDAT 234 Query: 232 HITLQDIVVDGGST 245 ++ +V+DG T Sbjct: 235 YVNGAALVMDGAYT 248 >1DOH-A nrPDB Length = 283 Score = 205 bits (523), Expect = 1e-53, Method: Composition-based stats. Identities = 57/260 (21%), Positives = 109/260 (41%), Gaps = 17/260 (6%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPF-----------ATEV 50 GK VTGAG+GIG A+ G KV T+ A Sbjct: 26 SLEGKVALVTGAGRGIGREMAMELGRRGCKVIVNYANSTESAEEVVAAIKKNGSDAACVK 85 Query: 51 MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 +V + ++ + + +LD + + +G++ G ++ E++ + F +N G F + Sbjct: 86 ANVGVVEDIVRMFEEAVKIFGKLDIVCSNSGVVSFGHVKDVTPEEFDRVFTINTRGQFFV 145 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAH-TPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 ++ + GG ++ + S + Y SK A+++ A + +++A + Sbjct: 146 AREAYKHL--EIGGRLILMGSITGQAKAVPKHAVYSGSKGAIETFARCMAIDMADKKITV 203 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGI---PLGKIARPQEIANTILFLA 226 NVV+PG TDM + + + + PL ++ P +IA + FLA Sbjct: 204 NVVAPGGIKTDMYHAVCREYIPNGENLSNEEVDEYAAVQWSPLRRVGLPIDIARVVCFLA 263 Query: 227 SDLASHITLQDIVVDGGSTL 246 S+ +T + I +DGG+ + Sbjct: 264 SNDGGWVTGKVIGIDGGACM 283 >2HSD-A nrPDB Length = 253 Score = 204 bits (520), Expect = 3e-53, Method: Composition-based stats. Identities = 74/253 (29%), Positives = 112/253 (44%), Gaps = 17/253 (6%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD-------QAFTQEQYPFATEVMDVA 54 D SGK V +TG +G+G A V AGA+V D + + +DV Sbjct: 2 DLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDVT 61 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 +V E +D LVN AGI + S E +++ +N+ G F + Sbjct: 62 IEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVEINLTGVFIGMKTV 121 Query: 115 MNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSP 174 + + GG+IV ++S A S+YGASK ++ L+ +EL +R N V P Sbjct: 122 IPAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVHP 181 Query: 175 GSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHIT 234 G T T M + GE P+G++ P EIA ++ L SD +S++T Sbjct: 182 GMTYTPMTAETGIRQ----------GEGNYPNTPMGRVGEPGEIAGAVVKLLSDTSSYVT 231 Query: 235 LQDIVVDGGSTLG 247 ++ VDGG T G Sbjct: 232 GAELAVDGGWTTG 244 >3R3S-A nrPDB Length = 294 Score = 204 bits (520), Expect = 3e-53, Method: Composition-based stats. Identities = 69/259 (26%), Positives = 112/259 (43%), Gaps = 23/259 (8%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQE------------QYPFATE 49 + VTG GIG A A+A+ GA V +E Sbjct: 46 RLKDRKALVTGGDSGIGRAAAIAYAREGADVAINYLPAEEEDAQQVKALIEECGRKAVLL 105 Query: 50 VMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGA-TDQLSKEDWQQTFAVNVGGAF 108 D++D + + + LD L AG L+ E +QQTFAVNV F Sbjct: 106 PGDLSDESFARSLVHKAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQTFAVNVFALF 165 Query: 109 NLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVR 168 + Q+ + + G +I+T +S A+ P + Y A+KAA+ + + + ++A G+R Sbjct: 166 WITQEAIPLLPK--GASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIR 223 Query: 169 CNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASD 228 N+V+PG T +Q + + D QF P+ + +P E+A ++LAS Sbjct: 224 VNIVAPGPIWTALQISGGQTQDK--------IPQFGQQTPMKRAGQPAELAPVYVYLASQ 275 Query: 229 LASHITLQDIVVDGGSTLG 247 +S++T + V GG LG Sbjct: 276 ESSYVTAEVHGVCGGEHLG 294 >3A28-C nrPDB Length = 258 Score = 204 bits (519), Expect = 4e-53, Method: Composition-based stats. Identities = 73/257 (28%), Positives = 115/257 (44%), Gaps = 22/257 (8%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV------------MDV 53 K VTG +GIG + G + D +EQ ++ +DV Sbjct: 3 KVAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQEEQAAETIKLIEAADQKAVFVGLDV 62 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 D A + D LVN AGI ++ ++++ED +Q ++VNV F Q Sbjct: 63 TDKANFDSAIDEAAEKLGGFDVLVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQA 122 Query: 114 TMNQFRRQR-GGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVV 172 +F G I+ AS AA +SAY +K A++ L + ELA G N Sbjct: 123 ASRKFDELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQELAPKGHTVNAY 182 Query: 173 SPGSTDTDMQRTLWVSDDAEEQRIRGFG-----EQFKLGIPLGKIARPQEIANTILFLAS 227 +PG T M W DAE +I G +++ I LG+ + P+++A + FLAS Sbjct: 183 APGIVGTGM----WEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLAS 238 Query: 228 DLASHITLQDIVVDGGS 244 + ++++T Q ++VDGG Sbjct: 239 ENSNYVTGQVMLVDGGM 255 >5EJ2-A nrPDB Length = 308 Score = 203 bits (516), Expect = 7e-53, Method: Composition-based stats. Identities = 63/273 (23%), Positives = 103/273 (37%), Gaps = 31/273 (11%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPF----------------- 46 +GK +++GA +G G + A+ + GA + D E + Sbjct: 36 AGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETADLVKD 95 Query: 47 -----ATEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGA-TDQLSKEDWQQTF 100 T +DV D + + + RLD +V AG+ G ++ WQ Sbjct: 96 LDRRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTDGRKLHKIRDNVWQDMI 155 Query: 101 AVNVGGAFNLFQQTMNQ-FRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVG 159 +N+ G ++ + + RGG+IV +S Y A+K + L + Sbjct: 156 DINLTGVWHTVKAGVPHVLSGGRGGSIVLTSSVGGRKAYPNTGHYIAAKHGVIGLMRAFA 215 Query: 160 LELAGSGVRCNVVSPGSTDTDMQRT----LWVSDDAEEQRIRGFGE--QFKLGIPLGKIA 213 +EL +R N V P T M D E F Q +P+ Sbjct: 216 VELGPHMIRVNAVLPTQVSTTMVMNDQTFRLFRPDLENPGPDDFAPISQMMHTLPVP-WV 274 Query: 214 RPQEIANTILFLASDLASHITLQDIVVDGGSTL 246 +I+N +LFLASD + ++T + VD GS L Sbjct: 275 DASDISNAVLFLASDESRYVTGVSLPVDAGSLL 307 >4AVY-A nrPDB Length = 242 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 71/246 (28%), Positives = 108/246 (43%), Gaps = 19/246 (7%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGF----DQAFTQEQYPFATEVMDVADAAQ 58 ++G+ V VTG GIG A A+ F E GA+V D E +D+ D+ + Sbjct: 9 YAGQQVLVTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHAPRHPRIRREELDITDSQR 68 Query: 59 VAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQF 118 + ++ + L RLD LVN AGI R ++ +++ +N+ A Q Sbjct: 69 LQRLFEALP----RLDVLVNNAGISRDR--EEYDLATFERVLRLNLSAAMLASQLARPLL 122 Query: 119 RRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTD 178 QRGG+I+ +AS + AY ASK A+ L S+ E A +R N ++PG D Sbjct: 123 -AQRGGSILNIASMYSTFGSADRPAYSASKGAIVQLTRSLACEYAAERIRVNAIAPGWID 181 Query: 179 TDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDI 238 T + L +A + PL + E+A+ FL AS +T + Sbjct: 182 TPLGAGLKADVEA--------TRRIMQRTPLARWGEAPEVASAAAFLCGPGASFVTGAVL 233 Query: 239 VVDGGS 244 VDGG Sbjct: 234 AVDGGY 239 >3UN1-A nrPDB Length = 260 Score = 202 bits (514), Expect = 1e-52, Method: Composition-based stats. Identities = 66/250 (26%), Positives = 114/250 (45%), Gaps = 18/250 (7%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYP-FATEVMDVADAAQV 59 M K V +TGA +GIG A+ + +V ++ P T D++ Sbjct: 24 MRNQQKVVVITGASQGIGAGLVRAYRDRNYRVVATSRSIKPSADPDIHTVAGDISKPETA 83 Query: 60 AQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFR 119 ++ + + R+D+LVN AG+ ++++ED+ VNV G F++ Q+ + Sbjct: 84 DRIVREGIERFGRIDSLVNNAGVFLAKPFVEMTQEDYDHNLGVNVAGFFHITQRAAAEML 143 Query: 120 RQRGGAIVTVASDAAHTPRIGMSAYGAS--KAALKSLALSVGLELAGSGVRCNVVSPGST 177 +Q G IV++ + P +GM + AS K L ++ S+ +E + SGVR N VSPG Sbjct: 144 KQGSGHIVSITTSLVDQPMVGMPSALASLTKGGLNAVTRSLAMEFSRSGVRVNAVSPGVI 203 Query: 178 DTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQD 237 T M S P+G++ +++ + +L+L + A IT + Sbjct: 204 KTPMHPAETHST-------------LAGLHPVGRMGEIRDVVDAVLYL--EHAGFITGEI 248 Query: 238 IVVDGGSTLG 247 + VDGG G Sbjct: 249 LHVDGGQNAG 258 >2AG5-A nrPDB Length = 246 Score = 202 bits (514), Expect = 1e-52, Method: Composition-based stats. Identities = 76/252 (30%), Positives = 122/252 (48%), Gaps = 14/252 (5%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQY-----PFATEVMDVADA 56 GK + +T A +GIG A ALAF GAKV D ++ Q T V+DV Sbjct: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKK 62 Query: 57 AQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMN 116 Q+ Q + ERLD L N AG + G ++DW + +NV + + + + Sbjct: 63 KQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLP 118 Query: 117 QFRRQRGGAIVTVASDA-AHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPG 175 + Q+ G I+ ++S A + + Y +KAA+ L SV + G+RCN V PG Sbjct: 119 KMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPG 178 Query: 176 STDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITL 235 + DT + + E+ F ++ K G+ A +EIA ++LASD ++++T Sbjct: 179 TVDTPSLQERIQARGNPEEARNDFLKRQKT----GRFATAEEIAMLCVYLASDESAYVTG 234 Query: 236 QDIVVDGGSTLG 247 +++DGG +LG Sbjct: 235 NPVIIDGGWSLG 246 >1CYD-A nrPDB Length = 244 Score = 202 bits (514), Expect = 1e-52, Method: Composition-based stats. Identities = 72/251 (28%), Positives = 118/251 (47%), Gaps = 19/251 (7%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQ------AFTQEQYPFATEVMDVA 54 ++FSG VTGAGKGIG T A +GAKV + + +E +D+ Sbjct: 3 LNFSGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPGIEPVCVDLG 62 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 D ++ L +D LVN A ++ M +++KE + ++F+VN+ F + Q Sbjct: 63 DWDAT----EKALGGIGPVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNLRSVFQVSQMV 118 Query: 115 MNQFRRQR-GGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 + G+IV V+S AH + Y ++K A+ L ++ +EL +R N V+ Sbjct: 119 ARDMINRGVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMELGPHKIRVNSVN 178 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 P TDM + + + F + K PL K A +++ N+ILFL SD ++ Sbjct: 179 PTVVLTDMGKKVSADPE--------FARKLKERHPLRKFAEVEDVVNSILFLLSDRSAST 230 Query: 234 TLQDIVVDGGS 244 + I+VD G Sbjct: 231 SGGGILVDAGY 241 >4HP8-A nrPDB Length = 247 Score = 201 bits (513), Expect = 2e-52, Method: Composition-based stats. Identities = 62/247 (25%), Positives = 99/247 (40%), Gaps = 12/247 (4%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADA---AQ 58 G+ VTGA G+G A A+ AGA+V + E + A A Sbjct: 6 SLEGRKALVTGANTGLGQAIAVGLAAAGAEVVCAARRAPDETLDIIAKDGGNASALLIDF 65 Query: 59 VAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMN-Q 117 + + D LVN AGI+R + + S+ DW + VN+ F Q Sbjct: 66 ADPLAAKDSFTDAGFDILVNNAGIIRRADSVEFSELDWDEVMDVNLKALFFTTQAFAKEL 125 Query: 118 FRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGST 177 + R G +V +AS + I + +Y A+K + L + E A G+ N ++PG Sbjct: 126 LAKGRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTKLLANEWAAKGINVNAIAPGYI 185 Query: 178 DTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQD 237 +T+ L + IP G+ ++IA +FL+S A ++ Sbjct: 186 ETNNTEALRADA--------ARNKAILERIPAGRWGHSEDIAGAAVFLSSAAADYVHGAI 237 Query: 238 IVVDGGS 244 + VDGG Sbjct: 238 LNVDGGW 244 >4FC7-A nrPDB Length = 277 Score = 201 bits (513), Expect = 2e-52, Method: Composition-based stats. Identities = 64/256 (25%), Positives = 110/256 (42%), Gaps = 20/256 (7%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAF-----TQEQYPFAT------EVM 51 K ++TG G GIG+ A F+ G ++ + AT M Sbjct: 25 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 84 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 DV V + L E R+D L+N A + LS ++ ++ G FN+ Sbjct: 85 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 144 Query: 112 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 171 + +F R GG IV + + + + G++KAA+ ++ + +E +R N Sbjct: 145 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 204 Query: 172 VSPGSTD-TDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 230 ++PG T+ R L + ++ PL ++ EIA+++L+LAS LA Sbjct: 205 LAPGPISGTEGLRRLGGPQASLSTKVTAS--------PLQRLGNKTEIAHSVLYLASPLA 256 Query: 231 SHITLQDIVVDGGSTL 246 S++T +V DGG+ L Sbjct: 257 SYVTGAVLVADGGAWL 272 >3UF0-A nrPDB Length = 273 Score = 200 bits (510), Expect = 4e-52, Method: Composition-based stats. Identities = 78/252 (30%), Positives = 114/252 (45%), Gaps = 18/252 (7%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQ---------AFTQEQYPFATEVMD 52 +G+ VTGAG GIG A A + AGA V + + V D Sbjct: 28 SLAGRTAVVTGAGSGIGRAIAHGYARAGAHVLAWGRTDGVKEVADEIADGGGSAEAVVAD 87 Query: 53 VADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQ 112 +AD A V + L A R+D LVN AGI+ +++S W++ VN+ A+ L + Sbjct: 88 LADLEGAANVAEELAAT-RRVDVLVNNAGIIARAPAEEVSLGRWREVLTVNLDAAWVLSR 146 Query: 113 QTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVV 172 G IVT+AS + ++AY ASK A+ L ++ E AG GV N + Sbjct: 147 SFGTAMLAHGSGRIVTIASMLSFQGGRNVAAYAASKHAVVGLTRALASEWAGRGVGVNAL 206 Query: 173 SPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASH 232 +PG T L D+ + IP G+ A P+++ +FLASD AS+ Sbjct: 207 APGYVVTANTAALRADDE--------RAAEITARIPAGRWATPEDMVGPAVFLASDAASY 258 Query: 233 ITLQDIVVDGGS 244 + Q + VDGG Sbjct: 259 VHGQVLAVDGGW 270 >3U5T-A nrPDB Length = 267 Score = 200 bits (509), Expect = 6e-52, Method: Composition-based stats. Identities = 64/251 (25%), Positives = 103/251 (41%), Gaps = 22/251 (8%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFA-----------TEVMD 52 + K VTGA +GIG A A G V A T D Sbjct: 26 TNKVAIVTGASRGIGAAIAARLASDGFTVVINYAGKAAAAEEVAGKIEAAGGKALTAQAD 85 Query: 53 VADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQ 112 V+D A V ++ +D LVN AGI+ + + + + AVN+ G FN + Sbjct: 86 VSDPAAVRRLFATAEEAFGGVDVLVNNAGIMPLTTIAETGDAVFDRVIAVNLKGTFNTLR 145 Query: 113 QTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVV 172 + + R GG I+ +++ Y A+KA ++++ + EL G + N V Sbjct: 146 EAAQRLRV--GGRIINMSTSQVGLLHPSYGIYAAAKAGVEAMTHVLSKELRGRDITVNAV 203 Query: 173 SPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASH 232 +PG T TD+ E + ++F PL ++ PQ+IA + FLA + Sbjct: 204 APGPTATDLF---------LEGKSDEVRDRFAKLAPLERLGTPQDIAGAVAFLAGPDGAW 254 Query: 233 ITLQDIVVDGG 243 + Q + +GG Sbjct: 255 VNGQVLRANGG 265 >5B1Y-A nrPDB Length = 270 Score = 198 bits (505), Expect = 1e-51, Method: Composition-based stats. Identities = 75/250 (30%), Positives = 119/250 (47%), Gaps = 22/250 (8%) Query: 8 VWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV------------MDVAD 55 VTG +GIG AT L F G V ++ A E +DV D Sbjct: 26 ALVTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAEEARRLGSPEAYTVRVDVGD 85 Query: 56 AAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTM 115 V ++ R+ L+ LVNAAG+L++G ++ S +W++T VN+ G + + + + Sbjct: 86 PDSVTEMSSRVGELIPHLNVLVNAAGVLQLGGIEETSISEWEETLRVNLTGVYLVTKLLL 145 Query: 116 NQFRRQRGGAIVTVASDAAHTPR-IGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSP 174 R+ + +IV VAS A T + AY ASKA + L + ++LAG G+R N V+P Sbjct: 146 PLLRKAKWASIVNVASIAGETGNVVAGVAYSASKAGVIGLTKRLAVQLAGYGIRVNAVAP 205 Query: 175 GSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASD-LASHI 233 +TDM R+ + + E+ PL I +P+++A ILFLA + I Sbjct: 206 SFVETDMTRSFLDTPEKR--------ERIASLHPLKIILKPEDVAEAILFLADPRRSRGI 257 Query: 234 TLQDIVVDGG 243 T + ++ G Sbjct: 258 TGHVLSINAG 267 >2B4Q-A nrPDB Length = 276 Score = 197 bits (501), Expect = 4e-51, Method: Composition-based stats. Identities = 71/259 (27%), Positives = 110/259 (42%), Gaps = 22/259 (8%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQ---------EQYPFATEVMD 52 +G+ VTG +GIG A +EAGA+V + D Sbjct: 26 SLAGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYGDCQAIPAD 85 Query: 53 VADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQ 112 ++ A ++ Q L + RLD LVN AG A + W++ +NV F+ Q Sbjct: 86 LSSEAGARRLAQALGELSARLDILVNNAGTSWGAALESYPVSGWEKVMQLNVTSVFSCIQ 145 Query: 113 QTMNQFRR----QRGGAIVTVASDAAHTPRIGMS-AYGASKAALKSLALSVGLELAGSGV 167 Q + RR + ++ + S A + + AYG SKAAL L+ + EL G + Sbjct: 146 QLLPLLRRSASAENPARVINIGSVAGISAMGEQAYAYGPSKAALHQLSRMLAKELVGEHI 205 Query: 168 RCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLAS 227 NV++PG + M R + A E IP+G+ RP+E+A + LA Sbjct: 206 NVNVIAPGRFPSRMTRHIANDPQALEAD--------SASIPMGRWGRPEEMAALAISLAG 257 Query: 228 DLASHITLQDIVVDGGSTL 246 +++T I +DGG L Sbjct: 258 TAGAYMTGNVIPIDGGFHL 276 >3U4C-A nrPDB Length = 281 Score = 195 bits (496), Expect = 2e-50, Method: Composition-based stats. Identities = 61/256 (23%), Positives = 106/256 (41%), Gaps = 15/256 (5%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFT------------QEQYPFATEV 50 S + +V GA +GIG A AL + + + + Sbjct: 21 MSKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVLA 80 Query: 51 MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 D++D A + Q++ ++ RLD L+N D + ED TF + Sbjct: 81 GDMSDQHTRAGIFQKIESQCGRLDVLINNIPGGAPDTFDNCNIEDMTATFTQKTVAYIDA 140 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 ++ + ++ G I+ + + P M AAL + + ++ ++LA + N Sbjct: 141 IKRASSLMKQNEFGRIINIVGNLWKEPGANMFTNSMMNAALINASKNISIQLAPHNITVN 200 Query: 171 VVSPGSTDTDMQRTLWVSDDAEEQRI--RGFGEQFKLGIPLGKIARPQEIANTILFLASD 228 ++PG TD +V + ++ I + EQ GIP+ ++ +E A FLAS+ Sbjct: 201 CLNPGFIATDRYHQ-FVENVMKKNSISKQKAEEQIASGIPMKRVGSAEETAALAAFLASE 259 Query: 229 LASHITLQDIVVDGGS 244 AS+IT Q I DGGS Sbjct: 260 EASYITGQQISADGGS 275 >5JS6-A nrPDB Length = 274 Score = 194 bits (493), Expect = 4e-50, Method: Composition-based stats. Identities = 62/233 (26%), Positives = 108/233 (46%), Gaps = 13/233 (5%) Query: 22 ALAFVEAGAKVTGFD------QAFTQEQYPFATEVMDVADAAQVAQVCQRLLAETERLDA 75 AFV +GA+V D +A QE + DV V + + RLD Sbjct: 28 VRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDC 87 Query: 76 LVNAAGI-LRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAA 134 +VN AG ++ S + ++Q +N+ G + L + + R+ + G ++ ++S Sbjct: 88 VVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQ-GNVINISSLVG 146 Query: 135 HTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQ 194 + Y A+K A+ ++ ++ L+ + GVR N +SPG+ T LW A Sbjct: 147 AIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTP----LWEELAALMP 202 Query: 195 RIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDGGSTLG 247 R + L PLG++ +P E+ +FLAS+ A+ T +++V GG+ LG Sbjct: 203 DPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIELLVTGGAELG 254 >3V8B-A nrPDB Length = 283 Score = 192 bits (488), Expect = 1e-49, Method: Composition-based stats. Identities = 77/253 (30%), Positives = 118/253 (46%), Gaps = 14/253 (5%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQ----------EQYPFATEVMDVADA 56 +TGAG GIG ATALA G V + T+ DV+D Sbjct: 30 VALITGAGSGIGRATALALAADGVTVGALGRTRTEVEEVADEIVGAGGQAIALEADVSDE 89 Query: 57 AQVAQVCQRLLAETERLDALVNAAGILRM-GATDQLSKEDWQQTFAVNVGGAFNLFQQTM 115 Q+ + L+ + LD +V AGI + D L +W +T AVN+ G F T+ Sbjct: 90 LQMRNAVRDLVLKFGHLDIVVANAGINGVWAPIDDLKPFEWDETIAVNLRGTFLTLHLTV 149 Query: 116 NQFRRQRGGAIVTVASDAAHTPR--IGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 +++ GGAIV V+S G +AY A+KAA ++ + LEL +R N V Sbjct: 150 PYLKQRGGGAIVVVSSINGTRTFTTPGATAYTATKAAQVAIVQQLALELGKHHIRVNAVC 209 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHI 233 PG+ +T++ + + EE I + ++ I G+ R +++A I FL S+ A H+ Sbjct: 210 PGAIETNISDNTKLRHE-EETAIPVEWPKGQVPITDGQPGRSEDVAELIRFLVSERARHV 268 Query: 234 TLQDIVVDGGSTL 246 T + +DGG L Sbjct: 269 TGSPVWIDGGQGL 281 >1H5Q-A nrPDB Length = 265 Score = 190 bits (484), Expect = 4e-49, Method: Composition-based stats. Identities = 64/265 (24%), Positives = 116/265 (43%), Gaps = 29/265 (10%) Query: 1 MDFSGKNVWVTGAGKGIGYATALA-----------FVEAGAKVTGFDQAFTQEQYPFATE 49 + F K + VTG +GIG A A + A V ++ + Sbjct: 10 ISFVNKTIIVTGGNRGIGLAFTRAVAAAGANVAVIYRSAADAVEVTEKVGKEFGVKTKAY 69 Query: 50 VMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 DV++ V + Q++ A+ + L+ AG+ + +L+ ED+ + VNV G FN Sbjct: 70 QCDVSNTDIVTKTIQQIDADLGPISGLIANAGVSVVKPATELTHEDFAFVYDVNVFGVFN 129 Query: 110 LFQQTMNQF-RRQRGGAIVTVASD-------AAHTPRIGMSAYGASKAALKSLALSVGLE 161 + + ++Q+ G+IV +S ++ + Y +SKAA +L + E Sbjct: 130 TCRAVAKLWLQKQQKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSSKAACSNLVKGLAAE 189 Query: 162 LAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANT 221 A +G+R N +SPG +TD + + + IPL + A+P+E+ Sbjct: 190 WASAGIRVNALSPGYVNTDQTAHMD----------KKIRDHQASNIPLNRFAQPEEMTGQ 239 Query: 222 ILFLASDLASHITLQDIVVDGGSTL 246 + L SD A+++T + +DGG + Sbjct: 240 AILLLSDHATYMTGGEYFIDGGQLI 264 >3ZV3-A nrPDB Length = 281 Score = 189 bits (480), Expect = 1e-48, Method: Composition-based stats. Identities = 64/257 (24%), Positives = 104/257 (40%), Gaps = 15/257 (5%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATE-------VMDV 53 M +G+ +TG G+G A FV GA+V D++ + + V DV Sbjct: 1 MKLTGEVALITGGASGLGRALVDRFVAEGARVAVLDKSAERLRELEVAHGGNAVGVVGDV 60 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKED-----WQQTFAVNVGGAF 108 + +R LA ++D L+ AGI ED + F VNV G Sbjct: 61 RSLQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDIFHVNVKGYI 120 Query: 109 NLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVR 168 + + + R G++V S+A P G Y A+K A+ L + ELA VR Sbjct: 121 HAVKACLPALVSSR-GSVVFTISNAGFYPNGGGPLYTATKHAVVGLVRQMAFELAPH-VR 178 Query: 169 CNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLAS- 227 N V+PG +TD++ + + + K +P+G++ +E +F A+ Sbjct: 179 VNGVAPGGMNTDLRGPSSLGLSEQSISSVPLADMLKSVLPIGRMPALEEYTGAYVFFATR 238 Query: 228 DLASHITLQDIVVDGGS 244 + T + DGG Sbjct: 239 GDSLPATGALLNYDGGM 255 >4EGF-A nrPDB Length = 266 Score = 189 bits (480), Expect = 1e-48, Method: Composition-based stats. Identities = 86/259 (33%), Positives = 115/259 (44%), Gaps = 20/259 (7%) Query: 1 MDFSGKNVWVTGAGKGIGYATALA-------FVEAGAKVTGFDQAFTQEQYPFATEV--- 50 + GK +TGA KGIG A A V +G V+ D A F T+V Sbjct: 16 LRLDGKRALITGATKGIGADIARAFAAAGARLVLSGRDVSELDAARRALGEQFGTDVHTV 75 Query: 51 -MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 +D+A+ A++ +R LD LVN AGI + + T AVN+ Sbjct: 76 AIDLAEPDAPAELARRAAEAFGGLDVLVNNAGISHPQPVVDTDPQLFDATIAVNLRAPAL 135 Query: 110 LFQQTMNQFRRQR-GGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVR 168 L GGAI+TVAS AA P AY SKA L + EL G+R Sbjct: 136 LASAVGKAMVAAGEGGAIITVASAAALAPLPDHYAYCTSKAGLVMATKVLARELGPHGIR 195 Query: 169 CNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASD 228 N V P T+M + +W + I IPLG+ A P E+++ +++LASD Sbjct: 196 ANSVCPTVVLTEMGQRVWGDEAKSAPMI--------ARIPLGRFAVPHEVSDAVVWLASD 247 Query: 229 LASHITLQDIVVDGGSTLG 247 AS I DI VDGG T+G Sbjct: 248 AASMINGVDIPVDGGYTMG 266 >3GDF-A nrPDB Length = 267 Score = 188 bits (479), Expect = 1e-48, Method: Composition-based stats. Identities = 61/261 (23%), Positives = 107/261 (40%), Gaps = 27/261 (10%) Query: 1 MDFSGKNVWVTGAG--KGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV-------- 50 + GK V VTGA KG+G A E GA V + Q E+ Sbjct: 16 LSLKGKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKTYGIKA 75 Query: 51 ----MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGG 106 V ++ + ++A+ ++DA + AG S E W V++ G Sbjct: 76 KAYKCQVDSYESCEKLVKDVVADFGQIDAFIANAGATADSGILDGSVEAWNHVVQVDLNG 135 Query: 107 AFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIG--MSAYGASKAALKSLALSVGLELAG 164 F+ + + F+ + G++V AS + H ++Y +KA +A S+ E Sbjct: 136 TFHCAKAVGHHFKERGTGSLVITASMSGHIANFPQEQTSYNVAKAGCIHMARSLANEW-R 194 Query: 165 SGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILF 224 R N +SPG DT + + + + + IP+G+ +E+ ++ Sbjct: 195 DFARVNSISPGYIDTGLSDFV----------PKETQQLWHSMIPMGRDGLAKELKGAYVY 244 Query: 225 LASDLASHITLQDIVVDGGST 245 ASD +++ T D+++DGG T Sbjct: 245 FASDASTYTTGADLLIDGGYT 265 >2P91-A nrPDB Length = 285 Score = 188 bits (478), Expect = 2e-48, Method: Composition-based stats. Identities = 56/259 (21%), Positives = 97/259 (37%), Gaps = 24/259 (9%) Query: 3 FSGKNVWVTGAG--KGIGYATALAFVEAGAKVTGFD---------QAFTQEQYPFATEVM 51 GK +TG + I Y A +F GA++ + + Sbjct: 19 LEGKRALITGVANERSIAYGIAKSFHREGAQLAFTYATPKLEKRVREIAKGFGSDLVVKC 78 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRM----GATDQLSKEDWQQTFAVNVGGA 107 DV+ + + + L LD +V++ G S+E ++ ++V Sbjct: 79 DVSLDEDIKNLKKFLEENWGSLDIIVHSIAYAPKEEFKGGVIDTSREGFKIAMDISVYSL 138 Query: 108 FNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGV 167 L ++ + R GAIVT++ A + G +KAAL+S + ++A G Sbjct: 139 IALTRELLPLM-EGRNGAIVTLSYYGAEKVVPHYNVMGIAKAALESTVRYLAYDIAKHGH 197 Query: 168 RCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLAS 227 R N +S G T ++ E P GK +++ +T +FL S Sbjct: 198 RINAISAGPVKTLAAYSI--------TGFHLLMEHTTKVNPFGKPITIEDVGDTAVFLCS 249 Query: 228 DLASHITLQDIVVDGGSTL 246 D A IT + + VD G + Sbjct: 250 DWARAITGEVVHVDNGYHI 268 >1BDB-A nrPDB Length = 277 Score = 187 bits (475), Expect = 4e-48, Method: Composition-based stats. Identities = 66/257 (25%), Positives = 105/257 (40%), Gaps = 15/257 (5%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATE-------VMDV 53 M G+ V +TG G+G A FV GAKV D++ + V DV Sbjct: 1 MKLKGEAVLITGGASGLGRALVDRFVAEGAKVAVLDKSAERLAELETDHGDNVLGIVGDV 60 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMG-ATDQLSKE----DWQQTFAVNVGGAF 108 Q R +A ++D L+ AGI A L +E + + F +NV G Sbjct: 61 RSLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHINVKGYI 120 Query: 109 NLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVR 168 + + + RG I T+ S+A P G Y A+K A+ L + ELA VR Sbjct: 121 HAVKACLPALVASRGNVIFTI-SNAGFYPNGGGPLYTAAKHAIVGLVRELAFELAPY-VR 178 Query: 169 CNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLAS- 227 N V G ++D++ + ++ + K +P+G++ +E +F A+ Sbjct: 179 VNGVGSGGINSDLRGPSSLGMGSKAISTVPLADMLKSVLPIGRMPEVEEYTGAYVFFATR 238 Query: 228 DLASHITLQDIVVDGGS 244 A+ T + DGG Sbjct: 239 GDAAPATGALLNYDGGL 255 >1HXH-A nrPDB Length = 253 Score = 187 bits (475), Expect = 4e-48, Method: Composition-based stats. Identities = 66/249 (26%), Positives = 100/249 (40%), Gaps = 15/249 (6%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFAT-------EVMDVA 54 GK VTG G+G + GAKV D Q A DV+ Sbjct: 3 RLQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGERSMFVRHDVS 62 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 A V + L+ LVN AGIL G + ED+ + +N F QQ Sbjct: 63 SEADWTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRLEDFSRLLKINTESVFIGCQQG 122 Query: 115 MNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSG--VRCNVV 172 + + GG+I+ +AS ++ P + Y ASKAA+ +L + L G +R N + Sbjct: 123 IAAMKET-GGSIINMASVSSWLPIEQYAGYSASKAAVSALTRAAALSCRKQGYAIRVNSI 181 Query: 173 SPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASH 232 P T M + ++E + G+ P+ IA +LFLASD +S Sbjct: 182 HPDGIYTPMMQASLPKGVSKEMVLHDPKLNRA-----GRAYMPERIAQLVLFLASDESSV 236 Query: 233 ITLQDIVVD 241 ++ ++ D Sbjct: 237 MSGSELHAD 245 >4TRR-A nrPDB Length = 269 Score = 186 bits (473), Expect = 8e-48, Method: Composition-based stats. Identities = 64/260 (24%), Positives = 101/260 (38%), Gaps = 17/260 (6%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFV------------EAGAKVTGFDQAFTQEQYPFATE 49 + +GK VTGA GIG AL + GA + Sbjct: 11 NLNGKTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANAVA--DEINKAGGKAIGV 68 Query: 50 VMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 MDV + V ++ +D LV+ AGI + + S DW++ A++V GAF Sbjct: 69 AMDVTNEEAVNTGIDKVAEAFGSVDILVSNAGIQIVNPIENYSFADWKKMQAIHVDGAFL 128 Query: 110 LFQQTMNQF-RRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVR 168 + + + RGG ++ + S +H SAY +K L LA + E A VR Sbjct: 129 TTKAALKHMYKDDRGGVVIYMGSVHSHEASPLKSAYVTAKHGLLGLARVLAKEGAKHNVR 188 Query: 169 CNVVSPGSTDTDMQRTLWVSDDAEE--QRIRGFGEQFKLGIPLGKIARPQEIANTILFLA 226 +VV PG T + E + G Q++A T+LFL+ Sbjct: 189 SHVVCPGFVRTPLVDKQIPEQAKELGISEEEVIKKVMLGNTVDGVFTTVQDVAQTVLFLS 248 Query: 227 SDLASHITLQDIVVDGGSTL 246 + ++ +T Q +V G + Sbjct: 249 AFPSAALTGQSFIVSHGWFM 268 >4RGB-A nrPDB Length = 294 Score = 183 bits (466), Expect = 5e-47, Method: Composition-based stats. Identities = 63/270 (23%), Positives = 106/270 (39%), Gaps = 28/270 (10%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFAT------------- 48 G+ V++TGA +G G + A+ E GA + G D + P+ Sbjct: 22 SLDGRVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEETARLV 81 Query: 49 ---------EVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQT 99 DV D A + +V + + +D ++ AG++ ++ + E + Sbjct: 82 EKTGQEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLTNPDERDASEALRLG 141 Query: 100 FAVNVGGAFNLFQQTMNQFRRQR-GGAIVTVASDAAHT----PRIGMSAYGASKAALKSL 154 + + G +N FQ + + + GG ++ +S A R G AY SK A+ L Sbjct: 142 LDIMLIGVWNTFQVAIPHMKERGQGGNLIATSSMIALLDLTDGRGGTDAYLTSKLAITGL 201 Query: 155 ALSVGLELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIAR 214 S L LA +R N V+P + T M E+ +P + Sbjct: 202 VRSYALMLAADRIRVNGVAPTNCSTPMITENPALFKVIEENPHLVNAM-STALPDFPMIE 260 Query: 215 PQEIANTILFLASDLASHITLQDIVVDGGS 244 P++++N ILFL SD T + VD G Sbjct: 261 PRDVSNAILFLISDAGRSFTGSVLKVDAGM 290 >2GDZ-A nrPDB Length = 267 Score = 183 bits (465), Expect = 5e-47, Method: Composition-based stats. Identities = 67/254 (26%), Positives = 108/254 (42%), Gaps = 29/254 (11%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD----------QAFTQEQYPFAT--EVM 51 +GK VTGA +GIG A A A + GAKV D A ++ P T Sbjct: 6 NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLFIQC 65 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 DVAD Q+ ++++ RLD LVN AG+ +++W++T +N+ + Sbjct: 66 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVISGT 117 Query: 112 QQTMNQFRRQRGG---AIVTVASDAAHTPRIGMSAYGASKAALKSLALS--VGLELAGSG 166 ++ +Q GG I+ ++S A P Y ASK + S + L SG Sbjct: 118 YLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSG 177 Query: 167 VRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLA 226 VR N + PG +T + ++ + + + + K I I P IAN ++ L Sbjct: 178 VRLNAICPGFVNTAILESI--EKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLI 235 Query: 227 SDLASHITLQDIVV 240 D A + + + Sbjct: 236 EDDA--LNGAIMKI 247 >4M89-A nrPDB Length = 261 Score = 181 bits (459), Expect = 3e-46, Method: Composition-based stats. Identities = 67/262 (25%), Positives = 104/262 (39%), Gaps = 25/262 (9%) Query: 3 FSGKNVWVTG--AGKGIGYATALAFVEAGAKVTGFD---------QAFTQEQYPFATEVM 51 GK + +TG + + I Y A A E GA++ + E Sbjct: 4 LQGKKILITGMISERSIAYGIAKACREQGAELAFTYVVDKLEERVRKMAAELDSELVFRC 63 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILR-----MGATDQLSKEDWQQTFAVNVGG 106 DVA ++ QV L + LD LV++ G D +S+E + ++ Sbjct: 64 DVASDDEINQVFADLGKHWDGLDGLVHSIGFAPKEALSGDFLDSISREAFNTAHEISAYS 123 Query: 107 AFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSG 166 L + R R AIV ++ A + G +KA+L++ L G Sbjct: 124 LPALAKAARP-MMRGRNSAIVALSYLGAVRAIPNYNVMGMAKASLEAGIRFTAACLGKEG 182 Query: 167 VRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLA 226 +RCN +S G T L S A+ ++ G PL + +E+ NT FL Sbjct: 183 IRCNGISAGPIKT-----LAASGIADFGKLLG---HVAAHNPLRRNVTIEEVGNTAAFLL 234 Query: 227 SDLASHITLQDIVVDGGSTLGA 248 SDL+S IT + VDGG ++ A Sbjct: 235 SDLSSGITGEITYVDGGYSINA 256 >5TF4-A nrPDB Length = 274 Score = 179 bits (454), Expect = 1e-45, Method: Composition-based stats. Identities = 59/259 (22%), Positives = 105/259 (40%), Gaps = 25/259 (9%) Query: 3 FSGKNVWVTGAG--KGIGYATALAFVEAGAKVTGFDQA---------FTQEQYPFATEVM 51 GK + G + I + A AGA++ Q +E F Sbjct: 10 LYGKRGLILGLANNRSIAWGIAKTASSAGAELAFTYQGEAMKKRVEPLAEEVKGFVCGHC 69 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILR----MGATDQLSKEDWQQTFAVNVGGA 107 DV+D+A + V + + +LD LV+A G G +S+ ++ T ++V Sbjct: 70 DVSDSASIDAVFNTIEKKWGKLDFLVHAIGFSDKEELSGRYVDISESNFMMTMNISVYSL 129 Query: 108 FNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGV 167 L ++ GG+I+T+ A + G +KAAL++ + ++L + Sbjct: 130 TALTKRAEKLM--SDGGSILTLTYYGAEKVVPNYNVMGVAKAALEASVKYLAVDLGPKHI 187 Query: 168 RCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLAS 227 R N +S G T L S + + I + E PL + +E+ ++ L+L S Sbjct: 188 RVNAISAGPIKT-----LAASGIGDFRYILKWNEY---NAPLRRTVTIEEVGDSALYLLS 239 Query: 228 DLASHITLQDIVVDGGSTL 246 DL+ +T + VD G + Sbjct: 240 DLSRSVTGEVHHVDSGYNI 258 >2BGM-A nrPDB Length = 278 Score = 178 bits (453), Expect = 1e-45, Method: Composition-based stats. Identities = 60/236 (25%), Positives = 104/236 (44%), Gaps = 17/236 (7%) Query: 22 ALAFVEAGAKVTGFDQAFTQEQYP---------FATEVMDVADAAQVAQVCQRLLAETER 72 A FV GAKV D A Q + DV V + +A+ + Sbjct: 33 AKLFVRYGAKVVIADIADDHGQKVCNNIGSPDVISFVHCDVTKDEDVRNLVDTTIAKHGK 92 Query: 73 LDALVNAAGILRMGA--TDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVA 130 LD + G+L + ED+++ +NV GAF + + + G+IV A Sbjct: 93 LDIMFGNVGVLSTTPYSILEAGNEDFKRVMDINVYGAFLVAKHAARVMIPAKKGSIVFTA 152 Query: 131 SDAAHTPRIGMSA-YGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQRTLWVSD 189 S ++ T G+S Y A+K A+ L S+ EL G+R N VSP + + ++ D Sbjct: 153 SISSFTAGEGVSHVYTATKHAVLGLTTSLCTELGEYGIRVNCVSPYIVASPLLTDVFGVD 212 Query: 190 DAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDGGST 245 + + + K G + R +++A+ + +LA D + +++ ++V+DGG T Sbjct: 213 SSRVEELAHQAANLK-----GTLLRAEDVADAVAYLAGDESKYVSGLNLVIDGGYT 263 >5CFZ-A nrPDB Length = 305 Score = 178 bits (452), Expect = 2e-45, Method: Composition-based stats. Identities = 55/262 (20%), Positives = 105/262 (40%), Gaps = 26/262 (9%) Query: 3 FSGKNVWVTGAGK--GIGYATALAFVEAGAKVT---------GFDQAFTQEQYPFATEVM 51 SGK + VTG I Y A A GA++ G + F + Sbjct: 47 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 106 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATD-----QLSKEDWQQTFAVNVGG 106 DVA+ A + + L + D V++ G D +++E ++ ++ Sbjct: 107 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 166 Query: 107 AFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSG 166 + + + G A++T++ A + G +KA+L++ + + G Sbjct: 167 FVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 224 Query: 167 VRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLA 226 VR N +S G T L S + +++ E P+ + +++ N+ FL Sbjct: 225 VRVNAISAGPIRT-----LAASGIKDFRKMLAHCEAV---TPIRRTVTIEDVGNSAAFLC 276 Query: 227 SDLASHITLQDIVVDGGSTLGA 248 SDL++ I+ + + VDGG ++ A Sbjct: 277 SDLSAGISGEVVHVDGGFSIAA 298 >5O3Z-A nrPDB Length = 263 Score = 177 bits (450), Expect = 4e-45, Method: Composition-based stats. Identities = 59/255 (23%), Positives = 96/255 (37%), Gaps = 15/255 (5%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATE------------VMDVA 54 V G G+ +G +AG V D + T +D Sbjct: 8 VAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTINSRYGAGRAYGFKVDAT 67 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 D A V + + + R D LV +AG+ + Q D+ + VN+ G F ++ Sbjct: 68 DEASVEALARAVDETFGRADLLVYSAGVAKAAPITQFRLTDFDLSLQVNLVGYFLCSREF 127 Query: 115 MNQFRRQR-GGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVS 173 R G I+ + S + S Y A+K L S+ L+LA G+ + + Sbjct: 128 SKLMIRDGIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDLAEYGITVHSLM 187 Query: 174 PGSTDTDMQRTLWVSDDAEEQRI--RGFGEQFKLGIPLGKIARPQEIANTILFLASDLAS 231 G+ + AE+ I + +PL + Q++ N +LF ASD A+ Sbjct: 188 LGNLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPLKRGCDYQDVLNVLLFYASDKAA 247 Query: 232 HITLQDIVVDGGSTL 246 + T Q I V GG + Sbjct: 248 YCTGQSINVTGGQVM 262 >4JQC-A nrPDB Length = 282 Score = 176 bits (446), Expect = 9e-45, Method: Composition-based stats. Identities = 55/262 (20%), Positives = 105/262 (40%), Gaps = 26/262 (9%) Query: 3 FSGKNVWVTGAGK--GIGYATALAFVEAGAKVT---------GFDQAFTQEQYPFATEVM 51 SGK + VTG I Y A A GA++ G + F + Sbjct: 24 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 83 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATD-----QLSKEDWQQTFAVNVGG 106 DVA+ A + + L + D V++ G D +++E ++ ++ Sbjct: 84 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 143 Query: 107 AFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSG 166 + + + G A++T++ A + G +KA+L++ + + G Sbjct: 144 FVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 201 Query: 167 VRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLA 226 VR N +S G T L S + +++ E P+ + +++ N+ FL Sbjct: 202 VRVNAISAGPIRT-----LAASGIKDFRKMLAHCEAV---TPIRRTVTIEDVGNSAAFLC 253 Query: 227 SDLASHITLQDIVVDGGSTLGA 248 SDL++ I+ + + VDGG ++ A Sbjct: 254 SDLSAGISGEVVHVDGGFSIAA 275 >3PXX-A nrPDB Length = 287 Score = 175 bits (445), Expect = 1e-44, Method: Composition-based stats. Identities = 67/282 (23%), Positives = 105/282 (37%), Gaps = 48/282 (17%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFA------------------ 47 K V VTG +G G + A+ E GA + FD E + Sbjct: 11 KVVLVTGGARGQGRSHAVKLAEEGADIILFDICHDIETNEYPLATSRDLEEAGLEVEKTG 70 Query: 48 ----TEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVN 103 T +DV D A V++ +AE +LD +V AGI +GA L + + F V+ Sbjct: 71 RKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANAGICPLGA--HLPVQAFADAFDVD 128 Query: 104 VGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSA-----------YGASKAALK 152 G N + G +I+T S A Y +K + Sbjct: 129 FVGVINTVHAALPYL--TSGASIITTGSVAGLIAAAQPPGAGGPQGPGGAGYSYAKQLVD 186 Query: 153 SLALSVGLELAGSGVRCNVVSPGSTDTDMQRTLW--------VSDDAEEQRIRGFGEQFK 204 S L + +LA +R NV+ P + +TDM + + + + F Sbjct: 187 SYTLQLAAQLAPQSIRANVIHPTNVNTDMLNSAPMYRQFRPDLEAPSRADALLAFPAMQA 246 Query: 205 LGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDGGSTL 246 + P +I+N + FLASD + ++T VD G+ L Sbjct: 247 MPTP---YVEASDISNAVCFLASDESRYVTGLQFKVDAGAML 285 >2YW9-A nrPDB Length = 261 Score = 175 bits (444), Expect = 2e-44, Method: Composition-based stats. Identities = 64/261 (24%), Positives = 100/261 (38%), Gaps = 25/261 (9%) Query: 1 MDFSGKNVWVTGAG--KGIGYATALAFVEAGAKVTGFDQA---------FTQEQYPFATE 49 +D SGK V G + +G+A A EAGA+V QA + Sbjct: 4 VDLSGKKALVMGVTNQRSLGFAIAAKLKEAGAEVALSYQAERLRPEAEKLAEALGGALLF 63 Query: 50 VMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATD----QLSKEDWQQTFAVNVG 105 DV ++ + + LD LV+A A + ++DW V+ Sbjct: 64 RADVTQDEELDALFAGVKEAFGGLDYLVHAIAFAPREAMEGRYIDTRRQDWLLALEVSAY 123 Query: 106 GAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGS 165 + ++ R GG IVT+ A+ + +KAAL++ + EL Sbjct: 124 SLVAVARRAEPLLRE--GGGIVTLTYYASEKVVPKYNVMAIAKAALEASVRYLAYELGPK 181 Query: 166 GVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFL 225 GVR N +S G T R++ ++ PL + +E+ N LFL Sbjct: 182 GVRVNAISAGPVRTVAARSIPG--------FTKMYDRVAQTAPLRRNITQEEVGNLGLFL 233 Query: 226 ASDLASHITLQDIVVDGGSTL 246 S LAS IT + + VD G + Sbjct: 234 LSPLASGITGEVVYVDAGYHI 254 >4GKB-A nrPDB Length = 258 Score = 175 bits (444), Expect = 2e-44, Method: Composition-based stats. Identities = 74/255 (29%), Positives = 108/255 (42%), Gaps = 16/255 (6%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQ---------AFTQEQYPFATEVM 51 ++ K V VTG GIG A ++ E A F + A Q Q + Sbjct: 3 LNLQDKVVIVTGGASGIGGAISMRLAEERAIPVVFARHAPDGAFLDALAQRQPRATYLPV 62 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 ++ D AQ + +A RLD LVN AG+ G ++ + + N+ + + Sbjct: 63 ELQDDAQCRDAVAQTIATFGRLDGLVNNAGV-NDGIGLDAGRDAFVASLERNLIHYYAMA 121 Query: 112 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 171 + + R GAIV ++S A T + S Y ASK A +L + L GVR N Sbjct: 122 HYCVPHLKATR-GAIVNISSKTAVTGQGNTSGYCASKGAQLALTREWAVALREHGVRVNA 180 Query: 172 VSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLG-KIARPQEIANTILFLASDLA 230 V P T + R A + + +PLG + P EIA+T +FL S A Sbjct: 181 VIPAEVMTPLYRNW----IATFEDPEAKLAEIAAKVPLGRRFTTPDEIADTAVFLLSPRA 236 Query: 231 SHITLQDIVVDGGST 245 SH T + + VDGG T Sbjct: 237 SHTTGEWLFVDGGYT 251 >4CR6-A nrPDB Length = 271 Score = 175 bits (444), Expect = 2e-44, Method: Composition-based stats. Identities = 71/256 (27%), Positives = 106/256 (41%), Gaps = 20/256 (7%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD-----QAFTQEQYPFATEVMDVADA 56 +GK VTGA GIG AT A++ GA V D A E+ D+AD Sbjct: 12 RLAGKAAIVTGAAGGIGRATVEAYLREGASVVAMDLAPRLAATRYEEPGAIPIACDLADR 71 Query: 57 AQVAQVCQRLLAETERLDALVNAAGI-LRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTM 115 A + +A LD LV + G LS DW + VN+ G F + Sbjct: 72 AAIDAAMADAVARLGGLDILVAGGALKGGTGNFLDLSDADWDRYVDVNMTGTFLTCRAGA 131 Query: 116 NQF------RRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 + R I+T+ S + +AY A+K + L ++ ++LA G+ Sbjct: 132 RAMVAAGAGKDGRSARIITIGSVNSFMAEPEAAAYVAAKGGVAMLTRAMAVDLARHGILV 191 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N+++PG D T + EQ + LG+ P+E+A +FLA D Sbjct: 192 NMIAPGPVDVTGNNTGYSEPR--------LAEQVLDEVALGRPGLPEEVATAAVFLAEDG 243 Query: 230 ASHITLQDIVVDGGST 245 +S IT I +DGG + Sbjct: 244 SSFITGSTITIDGGLS 259 >4NR0-A nrPDB Length = 273 Score = 174 bits (441), Expect = 4e-44, Method: Composition-based stats. Identities = 60/264 (22%), Positives = 100/264 (37%), Gaps = 27/264 (10%) Query: 3 FSGKNVWVTGAGK--GIGYATALAFVEAGAKVTGFDQAFTQEQY-----------PFATE 49 +GK + G I A A GA++ Q P Sbjct: 4 LTGKRALIVGVASKLSIASGIAAAMHREGAELAFTYQNDKLRGRVEEFASGWGSRPELCF 63 Query: 50 VMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQ-----LSKEDWQQTFAVNV 104 DVAD +Q+ V L + LD +V++ G D ++E ++ ++ Sbjct: 64 PCDVADDSQIEAVFAALGKHWDGLDIIVHSVGFAPGDQLDGDFTAVTTREGFRIAHDISA 123 Query: 105 GGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAG 164 L + + + R G+++T++ A + G +KA+L++ + L Sbjct: 124 YSFIALAKAG-REMMKGRNGSLLTLSYLGAERTMPNYNVMGMAKASLEAGVRYLAGSLGA 182 Query: 165 SGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILF 224 G R N VS G T L S +++ E+ PL + +E+ N F Sbjct: 183 EGTRVNAVSAGPIRT-----LAASGIKSFRKMLAANER---QTPLRRNVTIEEVGNAGAF 234 Query: 225 LASDLASHITLQDIVVDGGSTLGA 248 L SDLAS I+ + + VDGG A Sbjct: 235 LCSDLASGISGEILYVDGGFNTTA 258 >3GRK-A nrPDB Length = 293 Score = 173 bits (439), Expect = 6e-44, Method: Composition-based stats. Identities = 61/258 (23%), Positives = 102/258 (39%), Gaps = 25/258 (9%) Query: 3 FSGKNVWVTGAG--KGIGYATALAFVEAGAKVTGFDQA---------FTQEQYPFATEVM 51 GK + G + I + A A EAGA++ Q +E F Sbjct: 29 LQGKRGLILGVANNRSIAWGIAKAAREAGAELAFTYQGDALKKRVEPLAEELGAFVAGHC 88 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILR----MGATDQLSKEDWQQTFAVNVGGA 107 DVADAA + V + L + +LD LV+A G G S+ ++ T ++V Sbjct: 89 DVADAASIDAVFETLEKKWGKLDFLVHAIGFSDKDELTGRYIDTSEANFTNTMLISVYSL 148 Query: 108 FNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGV 167 + ++ GG+I+T+ A + G +KAAL++ + ++L + Sbjct: 149 TAVSRRAEKLMAD--GGSILTLTYYGAEKVMPNYNVMGVAKAALEASVKYLAVDLGPQNI 206 Query: 168 RCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLAS 227 R N +S G T L S + + I + E PL + E+ + L+ S Sbjct: 207 RVNAISAGPIKT-----LAASGIGDFRYILKWNEY---NAPLRRTVTIDEVGDVGLYFLS 258 Query: 228 DLASHITLQDIVVDGGST 245 DL+ +T + D G Sbjct: 259 DLSRSVTGEVHHADSGYH 276 >4J3F-A nrPDB Length = 280 Score = 172 bits (436), Expect = 1e-43, Method: Composition-based stats. Identities = 57/258 (22%), Positives = 101/258 (39%), Gaps = 24/258 (9%) Query: 3 FSGKNVWVTG--AGKGIGYATALAFVEAGAKVTGFD--------QAFTQEQYPFATEVMD 52 +GK + +TG + K I Y A A GA++ + E P A D Sbjct: 24 LAGKKILITGLLSNKSIAYGIAKAMHREGAELAFTYVGQFKDRVEKLCAEFNPAAVLPCD 83 Query: 53 VADAAQVAQVCQRLLAETERLDALVNAAGILR-----MGATDQLSKEDWQQTFAVNVGGA 107 V ++ + L + LDA+V++ D +++E + ++ Sbjct: 84 VISDQEIKDLFVELGKVWDGLDAIVHSIAFAPRDQLEGNFIDCVTREGFSIAHDISAYSF 143 Query: 108 FNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGV 167 L ++ + R ++V + A + G +KA+L++ L L G+ Sbjct: 144 AALAKEG-RSMMKNRNASMVALTYIGAEKAMPSYNTMGVAKASLEATVRYTALALGEDGI 202 Query: 168 RCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLAS 227 + N VS G T L S + +++ + PL K E+ NT+ FL S Sbjct: 203 KVNAVSAGPIKT-----LAASGISNFKKMLDYNAMVS---PLKKNVDIMEVGNTVAFLCS 254 Query: 228 DLASHITLQDIVVDGGST 245 D+A+ IT + + VD G Sbjct: 255 DMATGITGEVVHVDAGYH 272 >4ZJU-A nrPDB Length = 275 Score = 172 bits (436), Expect = 2e-43, Method: Composition-based stats. Identities = 51/259 (19%), Positives = 96/259 (37%), Gaps = 25/259 (9%) Query: 3 FSGKNVWVTGAGK--GIGYATALAFVEAGAKVTGFD---------QAFTQEQYPFATEVM 51 +GK + G I Y A A GA++ F ++ Sbjct: 14 LAGKRFLIAGVASKLSIAYGIAQALHREGAELAFTYPNEKLKKRVDEFAEQFGSKLVFPC 73 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILR----MGATDQLSKED-WQQTFAVNVGG 106 DVA A++ L + +D +V++ G G ++ D ++ ++ Sbjct: 74 DVAVDAEIDNAFAELAKHWDGVDGVVHSIGFAPAHTLDGDFTDVTDRDGFKIAHDISAYS 133 Query: 107 AFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSG 166 + + + ++ G ++T+ + + G +KA+L++ + L G Sbjct: 134 FVAMARAAKPLLQARQ-GCLLTLTYQGSERVMPNYNVMGMAKASLEAGVRYLASSLGVDG 192 Query: 167 VRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLA 226 +R N +S G T L S +++ E+ PL + +E+ N LFL Sbjct: 193 IRVNAISAGPIRT-----LAASGIKSFRKMLDANEKVA---PLKRNVTIEEVGNAALFLC 244 Query: 227 SDLASHITLQDIVVDGGST 245 S AS IT + + VD G Sbjct: 245 SPWASGITGEILYVDAGFN 263 >5KOI-A nrPDB Length = 293 Score = 171 bits (434), Expect = 3e-43, Method: Composition-based stats. Identities = 52/260 (20%), Positives = 102/260 (39%), Gaps = 26/260 (10%) Query: 3 FSGKNVWVTGAGK--GIGYATALAFVEAGAKVTGFDQA---------FTQEQYPFATEVM 51 GK + G + + A GA++ Q ++ Sbjct: 26 MQGKRGLIMGVANNHSLAWGIAKQLAAQGAELAFTYQGDALGKRVKPLAEQVGSDFVLPC 85 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGI-----LRMGATDQLSKEDWQQTFAVNVGG 106 DV D A V V + + + LD LV+A G L+ D ++E++ +T ++ Sbjct: 86 DVEDIATVDAVFEEIEKKWGGLDFLVHAIGFSDKTELKGRYADVTTRENFSRTMVISAYS 145 Query: 107 AFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSG 166 + Q+ + GG+I+T+ + + G +KAAL+++ + + G Sbjct: 146 FTEVAQRAEKLMKD--GGSILTLTYGGSTRTIPNYNVMGVAKAALEAMVRYLAADYGPQG 203 Query: 167 VRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLA 226 +R N +S G T L + + + I + + PL + ++ + ++L Sbjct: 204 IRVNAISAGPVRT-----LAGAGIGDARAIFSYQ---RRNSPLRRTVDIDDVGKSAVYLL 255 Query: 227 SDLASHITLQDIVVDGGSTL 246 SDL+S +T + VD G + Sbjct: 256 SDLSSGVTGEIHFVDSGYNI 275 >5I9N-A nrPDB Length = 276 Score = 169 bits (430), Expect = 6e-43, Method: Composition-based stats. Identities = 62/259 (23%), Positives = 102/259 (39%), Gaps = 26/259 (10%) Query: 3 FSGKNVWVTG--AGKGIGYATALAFVEAGAKVTGFD---------QAFTQEQYPFATEVM 51 GK + +TG + + I Y A A GA++ F E Sbjct: 4 LDGKRILLTGLLSNRSIAYGIAKACKREGAELAFTYVGDRFKDRITEFAAEFGSELVFPC 63 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILR-----MGATDQLSKEDWQQTFAVNVGG 106 DVAD AQ+ + L + LD LV++ G D L++E+++ ++ Sbjct: 64 DVADDAQIDALFASLKTHWDSLDGLVHSIGFAPREAIAGDFLDGLTRENFRIAHDISAYS 123 Query: 107 AFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSG 166 L + + +++T++ A + G +KAAL++ + + L G Sbjct: 124 FPALAKAALPMLSDD--ASLLTLSYLGAERAIPNYNTMGLAKAALEASVRYLAVSLGAKG 181 Query: 167 VRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLA 226 VR N +S G T L S +I F E PL + +++ N FL Sbjct: 182 VRVNAISAGPIKT-----LAASGIKSFGKILDFVE---SNSPLKRNVTIEQVGNAGAFLL 233 Query: 227 SDLASHITLQDIVVDGGST 245 SDLAS +T + + VD G Sbjct: 234 SDLASGVTAEVMHVDSGFN 252 >2X9N-A nrPDB Length = 288 Score = 169 bits (430), Expect = 7e-43, Method: Composition-based stats. Identities = 69/272 (25%), Positives = 101/272 (37%), Gaps = 45/272 (16%) Query: 8 VWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV------------MDVAD 55 VTGA K IG A A+ + G +V + A E+ D+ + Sbjct: 26 AVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTN 85 Query: 56 ----AAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKED----------WQQTFA 101 A ++ R D LVN A Q ED + Sbjct: 86 SNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDNSNGKTVETQVAELIG 145 Query: 102 VNVGGAFNLFQQTMNQFRRQRGG------AIVTVASDAAHTPRIGMSAYGASKAALKSLA 155 N F L + + +IV + P + S Y K AL L Sbjct: 146 TNAIAPFLLTMSFAQRQKGTNPNCTSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLT 205 Query: 156 LSVGLELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKI-AR 214 S LELA G+R N V+PG L V+ EE+ ++++ +PLG+ A Sbjct: 206 QSAALELAPYGIRVNGVAPGV------SLLPVAMGEEEK------DKWRRKVPLGRREAS 253 Query: 215 PQEIANTILFLASDLASHITLQDIVVDGGSTL 246 ++IA+ ++FL S A +IT I VDGG +L Sbjct: 254 AEQIADAVIFLVSGSAQYITGSIIKVDGGLSL 285 >3OML-A nrPDB Length = 613 Score = 169 bits (430), Expect = 8e-43, Method: Composition-based stats. Identities = 70/253 (27%), Positives = 105/253 (41%), Gaps = 40/253 (15%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMD-------- 52 + + G+ VTGAG G+G AL F E GAKV D T + D Sbjct: 15 LRYDGRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRK 74 Query: 53 -----VADAAQV---AQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNV 104 VAD V A+V + + R+D LVN AGILR + + S++DW V++ Sbjct: 75 AGGEAVADYNSVIDGAKVIETAIKAFGRVDILVNNAGILRDRSLVKTSEQDWNLVNDVHL 134 Query: 105 GGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAG 164 G+F Q ++Q G I+ +S++ G Y A+K L LA +V +E A Sbjct: 135 KGSFKCTQAAFPYMKKQNYGRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLANTVAIEGAR 194 Query: 165 SGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILF 224 + V CNV+ P + + M + E + P+ IA + + Sbjct: 195 NNVLCNVIVPTA-ASRMTEGILPDILFNELK-------------------PKLIAPVVAY 234 Query: 225 L----ASDLASHI 233 L D S+I Sbjct: 235 LCHESCEDNGSYI 247 >5IZ4-A nrPDB Length = 271 Score = 169 bits (428), Expect = 1e-42, Method: Composition-based stats. Identities = 71/262 (27%), Positives = 111/262 (42%), Gaps = 27/262 (10%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTG--FDQAFTQEQYPFATEV-----------MDV 53 +TG+ GIG ATAL F +AG V FD + DV Sbjct: 16 VCVITGSASGIGAATALRFAQAGWSVAIGNFDDSTRDAASTVEALCRDAGAQTLIFDADV 75 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAG---ILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 A + + +R+DAL+N AG ++ A DQ+ ++++ + VN+ G + + Sbjct: 76 GKDADCRHAVDMVASRWQRIDALINCAGTTRVIPHNAFDQIDDFEFERVYRVNLIGLYQM 135 Query: 111 FQQTMNQFRRQ----RGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSG 166 + + R R ++V V+S A AY ASK A+ +L LS+ LA Sbjct: 136 TRAAVPLLRESASATRSTSVVNVSSLAGLNGTGSSIAYAASKGAVNTLTLSLARNLAPH- 194 Query: 167 VRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLA 226 +R N ++PG D + + + G + PL +++RP EIA FL Sbjct: 195 IRVNALAPGMVDDGLLLRVL-----DAAAYDGVLSRMTESAPLKRVSRPAEIAELAWFL- 248 Query: 227 SDLASHITLQDIVVDGGSTLGA 248 + A IT Q I + G LG Sbjct: 249 TAHAPAITGQVIAAENGLLLGG 270 >1W73-A nrPDB Length = 302 Score = 169 bits (428), Expect = 1e-42, Method: Composition-based stats. Identities = 58/254 (22%), Positives = 100/254 (39%), Gaps = 19/254 (7%) Query: 2 DFSGKNVWVTGAG-----------KGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV 50 F GK ++TG G +G +A + +Q +Q Sbjct: 23 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 82 Query: 51 MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGA-FN 109 DV D V L+ + ++N A + T++LS W+ + + G F Sbjct: 83 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 142 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 + + Q+G A +++ + A T + ++KA +++++ S+ E G+R Sbjct: 143 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 202 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 NV+ PG T + E+ + G IP G++ +E+AN FL SD Sbjct: 203 NVIQPGPIKTKGAFSRLDPTGTFEKEMIG-------RIPCGRLGTVEELANLAAFLCSDY 255 Query: 230 ASHITLQDIVVDGG 243 AS I I DGG Sbjct: 256 ASWINGAVIKFDGG 269 >5JY1-A nrPDB Length = 274 Score = 168 bits (425), Expect = 3e-42, Method: Composition-based stats. Identities = 60/256 (23%), Positives = 96/256 (37%), Gaps = 20/256 (7%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTG----------FDQAFTQEQYPFATEVMD 52 + VTGAG GIG A +F GA V +Q + D Sbjct: 12 LEQRVALVTGAGGGIGRGVARSFGNEGAAVIIAEINESTGRQVEQEIREMGGRSLFVKTD 71 Query: 53 VADAAQVAQVCQRLLAETERLDALVNAAGI-LRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 V A + + + + LD LVN A + ++ + E +QT ++ + Sbjct: 72 VTSKASIEAAVRSAVEQFGSLDILVNNAFVPTPNVLLEEKTDEMLEQTLTTSLWATWWAM 131 Query: 112 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 171 + R +R G IV S T Y +KA + L S E + N Sbjct: 132 RAAFVPMRERRWGRIVNFYSIDTETGAWLHGDYNTAKAGIVGLTRSAASEWGRFNITVNA 191 Query: 172 VSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQ-EIANTILFLASDLA 230 ++P T M T + + F E+ PLG+ P+ +I +F AS+++ Sbjct: 192 IAP----TAMGATFFELAAKNPE----FAERSAAARPLGRSGDPEQDIGPAAVFFASEMS 243 Query: 231 SHITLQDIVVDGGSTL 246 +T + + VDGG L Sbjct: 244 RFVTGETLHVDGGLHL 259 >3OIG-A nrPDB Length = 266 Score = 164 bits (416), Expect = 3e-41, Method: Composition-based stats. Identities = 46/264 (17%), Positives = 97/264 (36%), Gaps = 27/264 (10%) Query: 2 DFSGKNVWVTGAG--KGIGYATALAFVEAGAKVT-----------GFDQAFTQEQYPFAT 48 G+N+ V G + I + A + EAGA++ + A T ++ Sbjct: 4 SLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSII 63 Query: 49 EVMDVADAAQVAQVCQRLLAETERLDALVNAAGILR----MGATDQLSKEDWQQTFAVNV 104 DV + A++ + + + + + +G +++ + ++ Sbjct: 64 LPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISS 123 Query: 105 GGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAG 164 + + GG+IVT+ + G +KA+L + + +L Sbjct: 124 YSLTAVVKAARPMMTE--GGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGK 181 Query: 165 SGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILF 224 +R N +S G T + + + + PL + P+E+ +T F Sbjct: 182 ENIRVNSISAGPIRTLSAKGI--------SDFNSILKDIEERAPLRRTTTPEEVGDTAAF 233 Query: 225 LASDLASHITLQDIVVDGGSTLGA 248 L SD++ IT +++ VD G + A Sbjct: 234 LFSDMSRGITGENLHVDSGFHITA 257 >4DA9-A nrPDB Length = 280 Score = 163 bits (412), Expect = 8e-41, Method: Composition-based stats. Identities = 60/257 (23%), Positives = 95/257 (36%), Gaps = 25/257 (9%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV-----------MDVAD 55 VTG +GIG A A +G + + P E+ D+AD Sbjct: 31 VAIVTGGRRGIGLGIARALAASGFDIAITGIGDAEGVAPVIAELSGLGARVIFLRADLAD 90 Query: 56 AAQVAQVCQRLLAETERLDALVNAAGILRM--GATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 + ++AE R+D LVN AGI + L E++ VN+ G Q Sbjct: 91 LSSHQATVDAVVAEFGRIDCLVNNAGIASIVRDDFLDLKPENFDTIVGVNLRGTVFFTQA 150 Query: 114 TMNQFRRQR---GGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 + +I+ + S +A Y SKA L + + + L LA +G+ Sbjct: 151 VLKAMLASDARASRSIINITSVSAVMTSPERLDYCMSKAGLAAFSQGLALRLAETGIAVF 210 Query: 171 VVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 230 V PG +DM + D + +P+ + P++I N + LA Sbjct: 211 EVRPGIIRSDMTAAVSGKYDGLIE---------SGLVPMRRWGEPEDIGNIVAGLAGGQF 261 Query: 231 SHITLQDIVVDGGSTLG 247 T I DGG ++G Sbjct: 262 GFATGSVIQADGGLSIG 278 >5YCX-A nrPDB Length = 266 Score = 159 bits (402), Expect = 1e-39, Method: Composition-based stats. Identities = 48/261 (18%), Positives = 93/261 (35%), Gaps = 27/261 (10%) Query: 3 FSGKNVWVTGAG--KGIGYATALAFVEAGAKVT-----------GFDQAFTQEQYPFATE 49 GK V G + I + A + AGAK+ + A T E Sbjct: 6 LQGKTFVVMGVANQRSIAWGIARSLHNAGAKLIFTYAGERLERNVRELADTLEGQESLVL 65 Query: 50 VMDVADAAQVAQVCQRLLAETERLDALVNAAGILRM----GATDQLSKEDWQQTFAVNVG 105 DV + ++ + + E + + + G S++ + ++ Sbjct: 66 PCDVTNDEELTACFETIKQEVGTIHGVAHCIAFANRDDLKGEFVDTSRDGFLLAQNISAF 125 Query: 106 GAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGS 165 + ++ GG I+T+ + G +KA+L++ + +L Sbjct: 126 SLTAVAREAKKVMTE--GGNILTLTYLGGERVVKNYNVMGVAKASLEASVKYLANDLGQH 183 Query: 166 GVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFL 225 G+R N +S G T + + + + PL + +E+ +T +FL Sbjct: 184 GIRVNAISAGPIRTLSAKGVG--------DFNSILREIEERAPLRRTTTQEEVGDTAVFL 235 Query: 226 ASDLASHITLQDIVVDGGSTL 246 SDLA +T ++I VD G + Sbjct: 236 FSDLARGVTGENIHVDSGYHI 256 >1A27-A nrPDB Length = 289 Score = 159 bits (402), Expect = 1e-39, Method: Composition-based stats. Identities = 55/242 (22%), Positives = 89/242 (36%), Gaps = 27/242 (11%) Query: 7 NVWVTGAGKGIGYATALAFVE---AGAKVTG-------------FDQAFTQEQYPFATEV 50 V +TG GIG A+ KV +A T Sbjct: 4 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 63 Query: 51 MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 +DV D+ VA +R+ R+D LV AG+ +G + L ++ VNV G + Sbjct: 64 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 121 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 Q + +R+ G ++ S Y ASK AL+ L S+ + L GV + Sbjct: 122 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLS 181 Query: 171 VVSPGSTDTDMQRTLWVSDDA--EEQRIRGFGEQFKLGIPLGKIAR-----PQEIANTIL 223 ++ G T + S + + I F ++ ++ R P+E+A Sbjct: 182 LIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV-- 239 Query: 224 FL 225 FL Sbjct: 240 FL 241 >2O23-A nrPDB Length = 265 Score = 158 bits (400), Expect = 2e-39, Method: Composition-based stats. Identities = 60/261 (22%), Positives = 97/261 (37%), Gaps = 32/261 (12%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFAT-------EVMDVA 54 G +TG G+G ATA V GA D + + DV Sbjct: 9 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVT 68 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQL------SKEDWQQTFAVNVGGAF 108 V + R+D VN AGI T L + ED+Q+ VN+ G F Sbjct: 69 SEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTF 128 Query: 109 NLFQQTMNQF------RRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLEL 162 N+ + + + + G I+ AS AA ++G +AY ASK + + L + +L Sbjct: 129 NVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 188 Query: 163 AGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLG-KIARPQEIANT 221 A G+R ++PG T + +L +P ++ P E A+ Sbjct: 189 APIGIRVMTIAPGLFGTPLLTSL----------PEKVCNFLASQVPFPSRLGDPAEYAHL 238 Query: 222 ILFLASDLASHITLQDIVVDG 242 + + + + I +DG Sbjct: 239 VQAII--ENPFLNGEVIRLDG 257 >6CGE-A nrPDB Length = 328 Score = 157 bits (398), Expect = 3e-39, Method: Composition-based stats. Identities = 55/242 (22%), Positives = 89/242 (36%), Gaps = 27/242 (11%) Query: 7 NVWVTGAGKGIGYATALAFVE---AGAKVTG-------------FDQAFTQEQYPFATEV 50 V +TG GIG A+ KV +A T Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 Query: 51 MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 +DV D+ VA +R+ R+D LV AG+ +G + L ++ VNV G + Sbjct: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 Query: 111 FQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCN 170 Q + +R+ G ++ S Y ASK AL+ L S+ + L GV + Sbjct: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLS 182 Query: 171 VVSPGSTDTDMQRTLWVSDDA--EEQRIRGFGEQFKLGIPLGKIAR-----PQEIANTIL 223 ++ G T + S + + I F ++ ++ R P+E+A Sbjct: 183 LIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV-- 240 Query: 224 FL 225 FL Sbjct: 241 FL 242 >3RKU-A nrPDB Length = 287 Score = 157 bits (397), Expect = 5e-39, Method: Composition-based stats. Identities = 61/239 (25%), Positives = 103/239 (43%), Gaps = 26/239 (10%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAG-------------AKVTGFDQAFTQE--QYPF 46 + K V +TGA GIG ATAL ++EA K+ + QE Sbjct: 30 RLAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPNAKV 89 Query: 47 ATEVMDVADAAQVAQVCQRLLAETERLDALVNAAG-ILRMGATDQLSKEDWQQTFAVNVG 105 +D+ A ++ + L E + +D LVN AG L Q++ ED Q F NV Sbjct: 90 HVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQIATEDIQDVFDTNVT 149 Query: 106 GAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGS 165 N+ Q + F+ + G IV + S A S Y ASK A+ + S+ EL + Sbjct: 150 ALINITQAVLPIFQAKNSGDIVNLGSIAGRDAYPTGSIYCASKFAVGAFTDSLRKELINT 209 Query: 166 GVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILF 224 +R +++PG +T+ + ++ + + + +K PL ++A+ I++ Sbjct: 210 KIRVILIAPGLVETEFSLVRYRGNEEQAKNV------YKDTTPL----MADDVADLIVY 258 >3K2E-A nrPDB Length = 296 Score = 155 bits (392), Expect = 2e-38, Method: Composition-based stats. Identities = 55/260 (21%), Positives = 94/260 (36%), Gaps = 25/260 (9%) Query: 1 MDFSGKNVWVTGAG--KGIGYATALAFVEAGAKVTGFDQA---------FTQEQYPFATE 49 M GK + G K + + A A GA+V + + T Sbjct: 26 MLMEGKKGVIIGVANDKSLAWGIAKAVCAQGAEVALTYLSETFKKRVDPLAESLGVKLTV 85 Query: 50 VMDVADAAQVAQVCQRLLAETERLDALVNAAGILRM----GATDQLSKEDWQQTFAVNVG 105 DV+DA V + + L E LD +V+A G S ++ + ++ Sbjct: 86 PCDVSDAESVDNMFKVLAEEWGSLDFVVHAVAFSDKNELKGRYVDTSLGNFLTSMHISCY 145 Query: 106 GAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGS 165 + + GG+I+T++ A + G KAAL++ + ++L Sbjct: 146 SFTYIASKAEPLM--TNGGSILTLSYYGAEKVVPHYNVMGVCKAALEASVKYLAVDLGKQ 203 Query: 166 GVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFL 225 +R N +S G T L S ++ I + K PL + ++ L+L Sbjct: 204 QIRVNAISAGPVRT-----LASSGISDFHYILTWN---KYNSPLRRNTTLDDVGGAALYL 255 Query: 226 ASDLASHITLQDIVVDGGST 245 SDL T + + VD G Sbjct: 256 LSDLGRGTTGETVHVDCGYH 275 >2QHX-A nrPDB Length = 328 Score = 154 bits (389), Expect = 4e-38, Method: Composition-based stats. Identities = 60/292 (20%), Positives = 95/292 (32%), Gaps = 66/292 (22%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFA------------TEVMDVA 54 VTGA K +G + A G V E + T D++ Sbjct: 48 VALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLS 107 Query: 55 DAAQ-----------------VAQVCQRLLAETERLDALVNAAGILRMGATDQLSKE--- 94 + A A++ R D LVN A + ++ Sbjct: 108 NVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHE 167 Query: 95 -----------DWQQTFAVNVGGAFNLFQQTM------NQFRRQRGGAIVTVASDAAHTP 137 F N + L + R +I+ + + P Sbjct: 168 PCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQP 227 Query: 138 RIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPG--STDTDMQRTLWVSDDAEEQR 195 +G + Y +K AL+ L S LELA +R N V PG DM +W Sbjct: 228 LLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLSVLVDDMPPAVW--------- 278 Query: 196 IRGFGEQFKLGIPL-GKIARPQEIANTILFLASDLASHITLQDIVVDGGSTL 246 E + +PL + + E+++ ++FL S A +IT + VDGG +L Sbjct: 279 -----EGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSL 325 >1E3W-A nrPDB Length = 261 Score = 153 bits (388), Expect = 5e-38, Method: Composition-based stats. Identities = 58/261 (22%), Positives = 97/261 (37%), Gaps = 32/261 (12%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFAT-------EVMDVA 54 G +TG G+G +TA V GA D ++ + +V Sbjct: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVT 66 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQL------SKEDWQQTFAVNVGGAF 108 +V + R+D VN AGI T + ED+Q+ VN+ G F Sbjct: 67 SEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTF 126 Query: 109 NLFQQTMNQF------RRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLEL 162 N+ + + + G I+ AS AA ++G +AY ASK + + L + +L Sbjct: 127 NVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL 186 Query: 163 AGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLG-KIARPQEIANT 221 A G+R ++PG T + TL +P ++ P E A+ Sbjct: 187 APIGIRVVTIAPGLFATPLLTTL----------PDTVRNFLASQVPFPSRLGDPAEYAHL 236 Query: 222 ILFLASDLASHITLQDIVVDG 242 + + + + I +DG Sbjct: 237 VQMVI--ENPFLNGEVIRLDG 255 >2BFA-A nrPDB Length = 288 Score = 153 bits (388), Expect = 6e-38, Method: Composition-based stats. Identities = 60/292 (20%), Positives = 95/292 (32%), Gaps = 66/292 (22%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFA------------TEVMDVA 54 VTGA K +G + A G V E + T D++ Sbjct: 8 VALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLS 67 Query: 55 DAAQ-----------------VAQVCQRLLAETERLDALVNAAGILRMGATDQLSKE--- 94 + A A++ R D LVN A + ++ Sbjct: 68 NVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHE 127 Query: 95 -----------DWQQTFAVNVGGAFNLFQQTM------NQFRRQRGGAIVTVASDAAHTP 137 F N + L + R +I+ + + P Sbjct: 128 PCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQP 187 Query: 138 RIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPG--STDTDMQRTLWVSDDAEEQR 195 +G + Y +K AL+ L S LELA +R N V PG DM +W Sbjct: 188 LLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLSVLVDDMPPAVW--------- 238 Query: 196 IRGFGEQFKLGIPL-GKIARPQEIANTILFLASDLASHITLQDIVVDGGSTL 246 E + +PL + + E+++ ++FL S A +IT + VDGG +L Sbjct: 239 -----EGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSL 285 >1P33-A nrPDB Length = 289 Score = 153 bits (388), Expect = 6e-38, Method: Composition-based stats. Identities = 64/290 (22%), Positives = 99/290 (34%), Gaps = 62/290 (21%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFA------------TEVMDVA 54 VTGA K +G + A A G V + A T D++ Sbjct: 9 VALVTGAAKRLGSSIAEALHAEGYTVCLHYHRSAADASTLAATLNARRPNSAITVQADLS 68 Query: 55 DAAQ-----------------VAQVCQRLLAETERLDALVNAAGILRMGATDQ------- 90 + A + + R D LVN A + Sbjct: 69 NVATASFSETDGSVPVTLFSRCSALVDACYMHWGRCDVLVNNASSFYPTPLLRKDAGEGG 128 Query: 91 ---LSKEDWQ----QTFAVNVGGAFNLFQQ----TMNQFRRQRGGA--IVTVASDAAHTP 137 KE + F N + L + + QRG + IV + P Sbjct: 129 SSVGDKESLEVAAADLFGSNAIAPYFLIKAFAQRVADTRAEQRGTSYSIVNMVDAMTSQP 188 Query: 138 RIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIR 197 +G + Y +K AL+ L S LELA +R N VSPG + + Sbjct: 189 LLGYTMYTMAKEALEGLTRSAALELASLQIRVNGVSPGLSVLP------------DDMPF 236 Query: 198 GFGEQFKLGIPL-GKIARPQEIANTILFLASDLASHITLQDIVVDGGSTL 246 E ++ +PL + + +E+++ ++FL S A +IT I VDGG +L Sbjct: 237 SVQEDYRRKVPLYQRNSSAEEVSDVVIFLCSPKAKYITGTCIKVDGGYSL 286 >4ALL-A nrPDB Length = 277 Score = 152 bits (385), Expect = 1e-37, Method: Composition-based stats. Identities = 44/262 (16%), Positives = 92/262 (35%), Gaps = 27/262 (10%) Query: 1 MDFSGKNVWVTGAG--KGIGYATALAFVEAGAKVTGFDQAFTQEQY-----------PFA 47 ++ K + G + I + A + GAK+ + + Sbjct: 23 LNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAH 82 Query: 48 TEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRM----GATDQLSKEDWQQTFAVN 103 +DV +V +++ + +D + ++ M G + S+E + ++ Sbjct: 83 LYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDIS 142 Query: 104 VGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELA 163 + + GG+IV + G +KA+L++ + L+L Sbjct: 143 SYSLTIVAHEAKKLMPE--GGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLG 200 Query: 164 GSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTIL 223 +R N +S G T + + ++ + PL + E+ T Sbjct: 201 PDNIRVNAISAGPIRTLSAKGVGG--------FNTILKEIEERAPLKRNVDQVEVGKTAA 252 Query: 224 FLASDLASHITLQDIVVDGGST 245 +L SDL+S +T ++I VD G Sbjct: 253 YLLSDLSSGVTGENIHVDSGFH 274 >2NWQ-A nrPDB Length = 272 Score = 152 bits (384), Expect = 2e-37, Method: Composition-based stats. Identities = 54/235 (22%), Positives = 96/235 (40%), Gaps = 21/235 (8%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQ---------EQYPFATEVMDVADAA 57 +++TGA G G A A F EAG + + + + +DV D A Sbjct: 23 TLFITGATSGFGEACARRFAEAGWSLVLTGRREERLQALAGELSAKTRVLPLTLDVRDRA 82 Query: 58 QVAQVCQRLLAETERLDALVNAAGILRMG-ATDQLSKEDWQQTFAVNVGGAFNLFQQTMN 116 ++ L E L L+N AG+ +DW N+ G + + Sbjct: 83 AMSAAVDNLPEEFATLRGLINNAGLALGTDPAQSCDLDDWDTMVDTNIKGLLYSTRLLLP 142 Query: 117 QFRRQRGG-AIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPG 175 + G +IV + S A P G YG +KA ++ +L++ +L G+GVR + PG Sbjct: 143 RLIAHGAGASIVNLGSVAGKWPYPGSHVYGGTKAFVEQFSLNLRCDLQGTGVRVTNLEPG 202 Query: 176 STDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 230 +++ + D A + + + P+ +P++IA TI ++ + A Sbjct: 203 LCESEFSLVRFGGDQAR------YDKTYAGAHPI----QPEDIAETIFWIMNQPA 247 >4NK4-A nrPDB Length = 301 Score = 149 bits (376), Expect = 1e-36, Method: Composition-based stats. Identities = 53/261 (20%), Positives = 101/261 (38%), Gaps = 25/261 (9%) Query: 3 FSGKNVWVTGAGK--GIGYATALAFVEAGAKVTGFD--QAFTQEQYPFATEV-------M 51 GK + G I + A AGA++ ++ + P A V Sbjct: 39 LKGKRGLIMGVANDHSIAWGIAKVLHSAGAQLAFSYQGESIGKRLKPLALTVDSDFMIPC 98 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILR----MGATDQLSKEDWQQTFAVNVGGA 107 +V D + + + +R+ E LD +V++ G S++++ QT V+ Sbjct: 99 NVEDPSSMDLLFERIKERWETLDFVVHSIAFSDKNELRGPYYNTSRDNFIQTMLVSCFSF 158 Query: 108 FNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGV 167 + ++ GGA++T+ + +A +K+AL+S + + G + Sbjct: 159 TEIVRRAAQLM--PHGGAMITLTYGGSMRVVPNYNAMAPAKSALESSTKYLACDYGGMNI 216 Query: 168 RCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLAS 227 R N +S G T ++ R K PL + ++I N+ L+L S Sbjct: 217 RINAISAGPVRTLAGASISNG--------RDIAAWSKENSPLKRTVSLEDIGNSALYLLS 268 Query: 228 DLASHITLQDIVVDGGSTLGA 248 L++ +T + VD G + A Sbjct: 269 YLSNGVTGEIHYVDCGYNIVA 289 >2PD3-A nrPDB Length = 275 Score = 141 bits (355), Expect = 3e-34, Method: Composition-based stats. Identities = 55/264 (20%), Positives = 103/264 (39%), Gaps = 28/264 (10%) Query: 3 FSGKNVWVTGAG--KGIGYATALAFVEAGAKVTG--FDQAFTQEQYPFATEV-------M 51 GK + G K I Y A + GA + +++ + P A E+ + Sbjct: 4 LKGKKGLIVGVANNKSIAYGIAQSCFNQGATLAFTYLNESLEKRVRPIAQELNSPYVYEL 63 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATD----QLSKEDWQQTFAVNVGGA 107 DV+ + + + LD +V++ A + + SK + ++V Sbjct: 64 DVSKEEHFKSLYNSVKKDLGSLDFIVHSVAFAPKEALEGSLLETSKSAFNTAMEISVYSL 123 Query: 108 FNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGV 167 L G +++T++ + + G +KAAL+S + ++L + Sbjct: 124 IELTNTLKPLL--NNGASVLTLSYLGSTKYMAHYNVMGLAKAALESAVRYLAVDLGKHHI 181 Query: 168 RCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLAS 227 R N +S G T L S A+ + I + E + PL K +E+ N ++L S Sbjct: 182 RVNALSAGPIRT-----LASSGIADFRMILKWNE---INAPLRKNVSLEEVGNAGMYLLS 233 Query: 228 DLASHITLQDIVVDGGST---LGA 248 L+S ++ + VD G +GA Sbjct: 234 SLSSGVSGEVHFVDAGYHVMGMGA 257 >5ILO-A nrPDB Length = 271 Score = 141 bits (355), Expect = 3e-34, Method: Composition-based stats. Identities = 57/214 (26%), Positives = 84/214 (39%), Gaps = 24/214 (11%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGA-KVTGFDQAFTQEQY----------PFATEV 50 F GKN VTG GIG + + AGA KV D E++ Sbjct: 12 SFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIK 71 Query: 51 MDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 MDVA+ V + + +D +VN AGI + +D Q+T VN+GG N Sbjct: 72 MDVANKKGVEATYEEIAKTFGNIDIVVNVAGI--------FNDKDVQRTLLVNLGGIINS 123 Query: 111 FQQTMNQFRRQRGGA---IVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLE--LAGS 165 + + GG +V ++S P + YGA+KA + + + E S Sbjct: 124 TLSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRS 183 Query: 166 GVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGF 199 G++ V PG+T TDM E + Sbjct: 184 GIKFVTVCPGATMTDMFTNFTEKIIFPETSDETY 217 >4DRY-A nrPDB Length = 281 Score = 139 bits (351), Expect = 1e-33, Method: Composition-based stats. Identities = 59/221 (26%), Positives = 87/221 (39%), Gaps = 25/221 (11%) Query: 21 TALAFVEAGAKVTG-------FDQAFTQEQYP----FATEVMDVADAAQVAQVCQRLLAE 69 A A G V D A + V DV D QVA + + AE Sbjct: 49 IAQALSAEGYSVVITGRRPDVLDAAAGEIGGRTGNIVRAVVCDVGDPDQVAALFAAVRAE 108 Query: 70 TERLDALVNAAGI-LRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQ--RGGAI 126 RLD LVN AG + ++++ E W A N+ GAF Q + Q RGG I Sbjct: 109 FARLDLLVNNAGSNVPPVPLEEVTFEQWNGIVAANLTGAFLCTQHAFRMMKAQTPRGGRI 168 Query: 127 VTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQRTLW 186 + S +A TPR + Y A+K A+ L S L+ + C + G+ TDM + Sbjct: 169 INNGSISAQTPRPNSAPYTATKHAITGLTKSTALDGRMHDIACGQIDIGNAATDMTARMS 228 Query: 187 VSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLAS 227 + + IP+ + IA ++++AS Sbjct: 229 TGVLQANGEVAA-----EPTIPI------EHIAEAVVYMAS 258 >2DKN-A nrPDB Length = 255 Score = 137 bits (345), Expect = 6e-33, Method: Composition-based stats. Identities = 70/265 (26%), Positives = 95/265 (35%), Gaps = 48/265 (18%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRL 66 + +TG+ GIG A AG V G D+ + D++ + Sbjct: 3 VIAITGSASGIGAALKELLARAGHTVIGIDRGQADIE-------ADLSTPGGRETAVAAV 55 Query: 67 LAETER-LDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGA 125 L LD LV AG+ A L AVN G L R + A Sbjct: 56 LDRCGGVLDGLVCCAGVGVTAANSGL-------VVAVNYFGVSALLDGLAEALSRGQQPA 108 Query: 126 IVTVASDAAHTPRIG--------------------------MSAYGASKAALKSLALSVG 159 V V S AA P AY SK A+ LA Sbjct: 109 AVIVGSIAATQPGAAELPMVEAMLAGDEARAIELAEQQGQTHLAYAGSKYAVTCLARRNV 168 Query: 160 LELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIA 219 ++ AG GVR NVV+PG+ +T + + A + R + PLG+ + P+E+A Sbjct: 169 VDWAGRGVRLNVVAPGAVETPLLQ-------ASKADPRYGESTRRFVAPLGRGSEPREVA 221 Query: 220 NTILFLASDLASHITLQDIVVDGGS 244 I FL AS I + VDGG Sbjct: 222 EAIAFLLGPQASFIHGSVLFVDGGM 246 >3E9N-A nrPDB Length = 245 Score = 136 bits (342), Expect = 1e-32, Method: Composition-based stats. Identities = 64/245 (26%), Positives = 96/245 (39%), Gaps = 23/245 (9%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVA 60 M K VTGA G+G V + E ++ ++ V Sbjct: 1 MSLKKKIAVVTGATGGMGIEIVKDLSRD-HIVYALGRNPEHLAALAEIEGVEPIESDIVK 59 Query: 61 QVCQRL----LAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMN 116 +V + L + +D LV+AA + R + S +W +NV L +Q + Sbjct: 60 EVLEEGGVDKLKNLDHVDTLVHAAAVARDTTIEAGSVAEWHAHLDLNVIVPAELSRQLLP 119 Query: 117 QFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGS 176 R G ++ + S A + P G + Y ASK AL+ LA + E A +G+R + VSPG Sbjct: 120 ALRAA-SGCVIYINSGAGNGPHPGNTIYAASKHALRGLADAFRKEEANNGIRVSTVSPGP 178 Query: 177 TDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQ 236 T+T M + L S + P+EIAN I F+ A T Q Sbjct: 179 TNTPMLQGLMDSQGTNFRPEI--------------YIEPKEIANAIRFVI--DAGETT-Q 221 Query: 237 DIVVD 241 VD Sbjct: 222 ITNVD 226 >3KZV-A nrPDB Length = 254 Score = 133 bits (334), Expect = 9e-32, Method: Composition-based stats. Identities = 48/191 (25%), Positives = 89/191 (46%), Gaps = 13/191 (6%) Query: 5 GKNVWVTGAGKGIGYATALAF--VEAGAKVTGFDQAFT-------QEQYPFATEVMDVAD 55 GK + VTG +GIG + ++ V G ++ + F V D+ + Sbjct: 2 GKVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARSEAPLKKLKEKYGDRFFYVVGDITE 61 Query: 56 AAQVAQVCQRLLAETERLDALVNAAGIL-RMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 + + Q+ + ++D+LV AG+L + +++ W++ + +N +L Sbjct: 62 DSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNEIDVNAWKKLYDINFFSIVSLVGIA 121 Query: 115 MNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSP 174 + + ++ G +V V+SDA + AYG+SKAAL A+++ E V+ V+P Sbjct: 122 LPELKKTN-GNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANE--ERQVKAIAVAP 178 Query: 175 GSTDTDMQRTL 185 G DTDMQ + Sbjct: 179 GIVDTDMQVNI 189 >2NTV-A nrPDB Length = 268 Score = 131 bits (330), Expect = 3e-31, Method: Composition-based stats. Identities = 57/264 (21%), Positives = 102/264 (38%), Gaps = 24/264 (9%) Query: 3 FSGKNVWVTG--AGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV--------MD 52 GK + V+G I + A EAGA++ + A + +D Sbjct: 4 LEGKRILVSGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLIQRIADRLPDKAPLIELD 63 Query: 53 VADAAQVAQVCQRLLAETE---RLDALVNAAGILR-----MGATDQLSKEDWQQTFAVNV 104 V + +A + +R+ AE +LD +V++ G + ED + ++ Sbjct: 64 VQNEEHLATLAERVTAEIGEGNKLDGVVHSIGFMPQTGMGTNQFFDAPYEDVSKGIHIST 123 Query: 105 GGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAG 164 +L + + GG+IV + D + +K+AL+S+ V E Sbjct: 124 YSYASLAKALL--LIMNSGGSIVGMDFD-PTRAMPAYNWMTVAKSALESVNRFVAREAGK 180 Query: 165 SGVRCNVVSPGSTDTDMQRTLWVSDDAEE--QRIRGFGEQFKLGIPLGK-IARPQEIANT 221 GVR N+V+ G T + EE +++ E + P+G + P +A T Sbjct: 181 YGVRSNLVAAGPIRTLAMSAIVGGAFGEEAGAQMQLLEEGWDQRAPIGWNMKDPTPVAKT 240 Query: 222 ILFLASDLASHITLQDIVVDGGST 245 + L S+ T I DGG++ Sbjct: 241 VCALLSEWLPATTGSIIYADGGAS 264 >3U9L-A nrPDB Length = 324 Score = 129 bits (325), Expect = 1e-30, Method: Composition-based stats. Identities = 53/247 (21%), Positives = 101/247 (40%), Gaps = 23/247 (9%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKV-------TGFDQAFTQEQYPFA------ 47 M S K + +TGA G G TA A AG +V G + + + FA Sbjct: 1 MVMSKKIILITGASSGFGRLTAEALAGAGHRVYASMRDIVGRNASNVEAIAGFARDNDVD 60 Query: 48 --TEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVG 105 T +DV V + +++ E R+D L++ AG + G + + E + + + +NV Sbjct: 61 LRTLELDVQSQVSVDRAIDQIIGEDGRIDVLIHNAGHMVFGPAEAFTPEQFAELYDINVL 120 Query: 106 GAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGM-SAYGASKAALKSLALSVGLELAG 164 + + + RRQ+ G ++ ++S ++ + Y A+KAA+ ++A+ EL+ Sbjct: 121 STQRVNRAALPHMRRQKHGLLIWISSSSSAGGTPPYLAPYFAAKAAMDAIAVQYARELSR 180 Query: 165 SGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILF 224 G+ +++ PG+ T S ++ + E +EI Sbjct: 181 WGIETSIIVPGAF-TSGTNHFAHSGVPDDHARQAEYEAGPNA------GLGEEIKKAFAA 233 Query: 225 LASDLAS 231 + A Sbjct: 234 IVPPDAD 240 >1FJH-A nrPDB Length = 257 Score = 129 bits (324), Expect = 1e-30, Method: Composition-based stats. Identities = 63/266 (23%), Positives = 99/266 (37%), Gaps = 50/266 (18%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRL 66 + ++G GIG AT AG ++ G D A + D++ A Q + Sbjct: 3 IIVISGCATGIGAATRKVLEAAGHQIVGID-------IRDAEVIADLSTAEGRKQAIADV 55 Query: 67 LAETER-LDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGA 125 LA+ + +D LV AG+ +VN GA L + ++ A Sbjct: 56 LAKCSKGMDGLVLCAGLGPQTKVLG-------NVVSVNYFGATELMDAFLPALKKGHQPA 108 Query: 126 IVTVASDAAH----------------------------TPRIGMSAYGASKAALKSLALS 157 V ++S A+ + G AY SK AL Sbjct: 109 AVVISSVASAHLAFDKNPLALALEAGEEAKARAIVEHAGEQGGNLAYAGSKNALTVAVRK 168 Query: 158 VGLELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQE 217 +GVR N ++PG+T+T + + E + P+G+ A P E Sbjct: 169 RAAAWGEAGVRLNTIAPGATETPLLQAGLQDPRYGESIAKFVP-------PMGRRAEPSE 221 Query: 218 IANTILFLASDLASHITLQDIVVDGG 243 +A+ I FL S AS++ IV+DGG Sbjct: 222 MASVIAFLMSPAASYVHGAQIVIDGG 247 >4OYR-A nrPDB Length = 289 Score = 127 bits (321), Expect = 3e-30, Method: Composition-based stats. Identities = 55/264 (20%), Positives = 100/264 (37%), Gaps = 24/264 (9%) Query: 3 FSGKNVWVTG--AGKGIGYATALAFVEAGAKVT--GFDQAFTQEQYPFATEV------MD 52 GK + V+G I + A E GA++ GFD+ ++ +D Sbjct: 25 LDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELD 84 Query: 53 VADAAQVAQVCQRLLAETE---RLDALVNAAGILR-----MGATDQLSKEDWQQTFAVNV 104 V + +A + R+ +LD +V++ G + + D + ++ Sbjct: 85 VQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISA 144 Query: 105 GGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAG 164 ++ + + GG+IV + D + + +K+AL+S+ V E Sbjct: 145 YSYASMAKALLPIM--NPGGSIVGMDFDPS-RAMPAYNWMTVAKSALESVNRFVAREAGK 201 Query: 165 SGVRCNVVSPGSTDTDMQRTLWVSDDAEE--QRIRGFGEQFKLGIPLGK-IARPQEIANT 221 GVR N+V+ G T + EE +I+ E + P+G + +A T Sbjct: 202 YGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKT 261 Query: 222 ILFLASDLASHITLQDIVVDGGST 245 + L SD T I DGG+ Sbjct: 262 VCALLSDWLPATTGDIIYADGGAH 285 >3PPI-A nrPDB Length = 281 Score = 126 bits (317), Expect = 9e-30, Method: Composition-based stats. Identities = 56/263 (21%), Positives = 101/263 (38%), Gaps = 37/263 (14%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFT-------QEQYPFATEVMDVA 54 F G + V+G G+G AT G V D A + +V Sbjct: 27 QFEGASAIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADELGNRAEFVSTNVT 86 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAG--------ILRMGATDQLSKEDWQQTFAVNVGG 106 V + + RL V A G + R G+ + + +T + + G Sbjct: 87 SEDSVLAAIEAA-NQLGRLRYAVVAHGGFGVAQRIVQRDGSPADMG--GFTKTIDLYLNG 143 Query: 107 AFNLFQ------QTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGL 160 +N+ + GA+V AS A + +IG +AY A+KA + L ++ Sbjct: 144 TYNVARLVAASIAAAEPRENGERGALVLTASIAGYEGQIGQTAYAAAKAGVIGLTIAAAR 203 Query: 161 ELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPL-GKIARPQEIA 219 +L+ +G+R N ++PG+ T + ++ +F IP ++ P E A Sbjct: 204 DLSSAGIRVNTIAPGTMKTPIMESVG----------EEALAKFAANIPFPKRLGTPDEFA 253 Query: 220 NTILFLASDLASHITLQDIVVDG 242 + FL ++ +I + + +DG Sbjct: 254 DAAAFLLTN--GYINGEVMRLDG 274 >1B15-A nrPDB Length = 254 Score = 126 bits (316), Expect = 1e-29, Method: Composition-based stats. Identities = 49/209 (23%), Positives = 82/209 (39%), Gaps = 23/209 (11%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAK-VTGFDQAFTQEQYPFATEV--------- 50 MD + KNV A GIG T+ V+ K D+ + Sbjct: 1 MDLTNKNVIFVAALGGIGLDTSRELVKRNLKNFVILDRVENPTALAELKAINPKVNITFH 60 Query: 51 -MDVADA-AQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAF 108 DV A+ ++ +++ + + +D L+N AGI L ++T A+N G Sbjct: 61 TYDVTVPVAESKKLLKKIFDQLKTVDILINGAGI--------LDDHQIERTIAINFTGLV 112 Query: 109 NLFQQTMNQFRRQRGGA---IVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGS 165 N ++ + +++GG I + S + Y ASKAA+ S S+ + Sbjct: 113 NTTTAILDFWDKRKGGPGGIIANICSVTGFNAIHQVPVYSASKAAVVSFTNSLAKLAPIT 172 Query: 166 GVRCNVVSPGSTDTDMQRTLWVSDDAEEQ 194 GV ++PG T T + T D E + Sbjct: 173 GVTAYSINPGITRTPLVHTFNSWLDVEPR 201 >4Q9N-A nrPDB Length = 298 Score = 121 bits (304), Expect = 3e-28, Method: Composition-based stats. Identities = 52/293 (17%), Positives = 94/293 (32%), Gaps = 58/293 (19%) Query: 1 MDFSGKNVWVTGAGK--GIGYATALAFVEAGAKV-------------------------- 32 +D +GK ++ G G G G+ A EAGA + Sbjct: 4 IDLTGKIAFIAGIGDDNGYGWGIAKMLAEAGATILVGTWVPIYKIFSQSLELGKFNASRE 63 Query: 33 ----------------TGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRLLAETERLDAL 76 FD Q + V++V +++ +D L Sbjct: 64 LSNGELLTFAKIYPMDASFDTPEDIPQEILENKRYKDLSGYTVSEVVEQVKKHFGHIDIL 123 Query: 77 VNAAGILR--MGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAA 134 V++ S++ + + + +L G + +++ A+ Sbjct: 124 VHSLANSPEIAKPLLDTSRKGYLAALSTSSYSFISLLSHFGPIMNA--GASTISLTYLAS 181 Query: 135 HTPRIGMSA-YGASKAALKSLALSVGLELAGS-GVRCNVVSPGSTDTDMQRTLWVSDDAE 192 G A+KAAL+S + E GVR N +S G + + + Sbjct: 182 MRAVPGYGGGMNAAKAALESDTKVLAWEAGRRWGVRVNTISAGPLASRAGKAIGF----- 236 Query: 193 EQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDGGST 245 I + ++ PL +++ FL S LAS IT + + VD G+ Sbjct: 237 ---IERMVDYYQDWAPLPSPMEAEQVGAAAAFLVSPLASAITGETLYVDHGAN 286 >2O2S-A nrPDB Length = 315 Score = 121 bits (303), Expect = 4e-28, Method: Composition-based stats. Identities = 55/293 (18%), Positives = 95/293 (32%), Gaps = 52/293 (17%) Query: 1 MDFSGKNVWVTGAGK--GIGYATALAFVEAGAKVT------------------------- 33 +D G+ +V G G G+A A AGA+V Sbjct: 5 IDLRGQTAFVAGVADSHGYGWAIAKHLASAGARVALGTWPPVLGLFQKSLQSGRLDEDRK 64 Query: 34 ---------GFDQAFTQEQYPFATEVMDVADAA--------QVAQVCQRLLAETERLDAL 76 D+ D + +V ++ + +D L Sbjct: 65 LPDGSLIEFAGVYPLDAAFDKPEDVPQDIKDNKRYAGVDGYTIKEVAVKVKQDLGNIDIL 124 Query: 77 VNAA--GILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAA 134 V++ G + S++ + + + +L Q GG+ VT++ AA Sbjct: 125 VHSLANGPEVTKPLLETSRKGYLAASSNSAYSFVSLLQHFGPIM--NEGGSAVTLSYLAA 182 Query: 135 HTPRIGMSA-YGASKAALKSLALSVGLELA-GSGVRCNVVSPGSTDTDMQRTLWVSDDAE 192 G ++KAAL+S ++ E GVR N +S G + + S E Sbjct: 183 ERVVPGYGGGMSSAKAALESDTRTLAWEAGQKYGVRVNAISAGPLKSRAASAIGKSG--E 240 Query: 193 EQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDGGST 245 + I + PL + ++ LFL S LA ++ + VD G Sbjct: 241 KSFIDYAIDYSYNNAPLRRDLHSDDVGGAALFLLSPLARAVSGVTLYVDNGLH 293 >1ENP-A nrPDB Length = 312 Score = 119 bits (298), Expect = 1e-27, Method: Composition-based stats. Identities = 55/296 (18%), Positives = 97/296 (32%), Gaps = 59/296 (19%) Query: 1 MDFSGKNVWVTGAGK--GIGYATALAFVEAGAKV-------------------------- 32 +D GK ++ G G G+A A + AGA++ Sbjct: 14 IDLRGKRAFIAGIADDNGYGWAVAKSLAAAGAEILVGTWVPALNIFETSLRRGKFDQSRV 73 Query: 33 ----------------TGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRLLAETERLDAL 76 FD + A + + V + + + + +D L Sbjct: 74 LPDGSLMEIKKVYPLDAVFDNPEDVPEDVKANKRYAGSSNWTVQEAAECVRQDFGSIDIL 133 Query: 77 VNAA--GILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAA 134 V++ G + S++ + + + +L + GGA +++ A+ Sbjct: 134 VHSLANGPEVSKPLLETSRKGYLAAISASSYSFVSLLSHFLPIM--NPGGASISLTYIAS 191 Query: 135 HTPRIGMSA-YGASKAALKSLALSVGLELAGS-GVRCNVVSPGSTDTDMQRTLWVSDDAE 192 G ++KAAL+S + E +R N +S G + + + Sbjct: 192 ERIIPGYGGGMSSAKAALESDTRVLAFEAGRKQNIRVNTISAGPLGSRAAKAIGF----- 246 Query: 193 EQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDGGS-TLG 247 I E P+ K E+ N FL S LAS IT I VD G ++G Sbjct: 247 ---IDTMIEYSYNNAPIQKTLTADEVGNAAAFLVSPLASAITGATIYVDNGLNSMG 299 >1MG5-A nrPDB Length = 255 Score = 116 bits (292), Expect = 8e-27, Method: Composition-based stats. Identities = 45/215 (20%), Positives = 78/215 (36%), Gaps = 23/215 (10%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAK-VTGFDQAFTQEQYPFATEV----------M 51 + KNV GIG T+ ++ K + D+ + Sbjct: 4 LTNKNVIFVAGLGGIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKVTVTFYPY 63 Query: 52 DVADA-AQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL 110 DV A+ ++ + + A+ + +D L+N AGI L ++T AVN G N Sbjct: 64 DVTVPIAETTKLLKTIFAQLKTVDVLINGAGI--------LDDHQIERTIAVNYTGLVNT 115 Query: 111 FQQTMNQFRRQRGGA---IVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGV 167 ++ + +++GG I + S + Y +KAA+ + S+ +GV Sbjct: 116 TTAILDFWDKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAKLAPITGV 175 Query: 168 RCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQ 202 V+PG T T + D E Q Sbjct: 176 TAYTVNPGITRTTLVHKFNSWLDVEPQVAEKLLAH 210 >4HBG-A nrPDB Length = 286 Score = 116 bits (291), Expect = 1e-26, Method: Composition-based stats. Identities = 50/282 (17%), Positives = 81/282 (28%), Gaps = 70/282 (24%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGF---DQAFTQEQYPFATEVMDVADAAQVAQVC 63 VTGA +GIG A + G ++ + ++ Q A Sbjct: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 Query: 64 QRLLAETER-----------------------------------------LDALVNAAGI 82 + ++ L+N AG+ Sbjct: 66 D--FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL 123 Query: 83 LRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRG-----------GAIVTVAS 131 + + + + Q VN + + + + IV ++S Sbjct: 124 TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 Query: 132 D--AAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTD-TDMQRTLWVS 188 + G S Y ASKAAL + E+ +RC +SPG TDM + L V Sbjct: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVE 243 Query: 189 DDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 230 E + I + P EIA + L S A Sbjct: 244 AK----------EMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 >3UCF-A nrPDB Length = 223 Score = 110 bits (275), Expect = 7e-25, Method: Composition-based stats. Identities = 51/240 (21%), Positives = 85/240 (35%), Gaps = 27/240 (11%) Query: 9 WVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRLLA 68 V G GIG A V + +D++D V + + Sbjct: 10 VVLGGTSGIGAELAKQLESEHTIVHVASRQTG----------LDISDEKSVYHYFETI-- 57 Query: 69 ETERLDALVNAAG-ILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAIV 127 D L+ AG G + + F GA + + +GG+I Sbjct: 58 --GAFDHLIVTAGSYAPAGKVVDVEVTQAKYAFDTKFWGAVLAAKHGARYLK--QGGSIT 113 Query: 128 TVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQRTLWV 187 + + A AA+++ + ELA +R N +SPG T T+ + + Sbjct: 114 LTSGMLSRKVVANTYVKAAINAAIEATTKVLAKELAP--IRVNAISPGLTKTEAYKGMNA 171 Query: 188 SDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDGGSTLG 247 D ++ + +P+GK+ +IA LF S++T I VDGG+ LG Sbjct: 172 DDR------DAMYQRTQSHLPVGKVGEASDIAMAYLFAI--QNSYMTGTVIDVDGGALLG 223 >2HRB-A nrPDB Length = 274 Score = 109 bits (272), Expect = 2e-24, Method: Composition-based stats. Identities = 43/254 (16%), Positives = 66/254 (25%), Gaps = 62/254 (24%) Query: 6 KNVWVTGAGKGIGYATALAF-----------VEAGAKVTGFDQAFTQEQYPFATEVMDVA 54 + VTGA +GIG A A A+ Q E +D+ Sbjct: 3 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDID 62 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQ--TFAVNVGGAFNLFQ 112 D + + L E L+ LVN A + D D + T N N+ Sbjct: 63 DLQSIRALRDFLRKEYGGLNVLVNNAAVAFKS--DDPMPFDIKAEMTLKTNFFATRNMCN 120 Query: 113 QTMNQFRRQRGGAIVTVASDAAHTPRIG-------------------------------- 140 + + + G +V ++S Sbjct: 121 ELLPIMKP--HGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKN 178 Query: 141 ---------MSAYGASKAALKSLALSVGLELAGS----GVRCNVVSPGSTDTDMQRTLWV 187 S YG SK + L+ + L + N PG TDM + Sbjct: 179 EVHEREGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDSI 238 Query: 188 SDDAEEQRIRGFGE 201 E + Sbjct: 239 RTVEEGAETPVYLA 252 >5PGZ-A nrPDB Length = 276 Score = 107 bits (269), Expect = 4e-24, Method: Composition-based stats. Identities = 39/191 (20%), Positives = 62/191 (32%), Gaps = 14/191 (7%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVT-----------GFDQAFTQEQYPFATEVM 51 GK V VTGA KGIG A + GA V + Sbjct: 16 LQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHYIAG 75 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 + D Q + LD L+ + ++ VN + Sbjct: 76 TMEDMTFAEQFIVKAGKLMGGLDMLILNHITQTSLSLFHDDIHSVRRVMEVNFLSYVVMS 135 Query: 112 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 171 + +Q G+I ++S A + ++ Y ASK AL ++ EL + V ++ Sbjct: 136 TAALP-MLKQSNGSIAVISSLAGKMTQPMIAPYSASKFALDGFFSTIRTELYITKVNVSI 194 Query: 172 VSP--GSTDTD 180 G DT+ Sbjct: 195 TLCVLGLIDTE 205 >3DWF-A nrPDB Length = 276 Score = 107 bits (268), Expect = 4e-24, Method: Composition-based stats. Identities = 41/191 (21%), Positives = 65/191 (34%), Gaps = 14/191 (7%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFA-----------TEVM 51 GK V VTGA KGIG A + GA V ++ Q A Sbjct: 9 LQGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASAHYIAG 68 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 + D + LD L+ + ++ +++ VN L Sbjct: 69 SMEDMTFAEEFVAEAGNLMGGLDMLILNHVLYNRLTFFHGEIDNVRKSMEVNFHSFVVLS 128 Query: 112 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 171 M + + G+I V+S A ++ Y ASK AL ++ E + V ++ Sbjct: 129 VAAMPMLMQSQ-GSIAVVSSVAGKITYPLIAPYSASKFALDGFFSTLRSEFLVNKVNVSI 187 Query: 172 VSP--GSTDTD 180 G DT+ Sbjct: 188 TLCILGLIDTE 198 >5L51-A nrPDB Length = 324 Score = 105 bits (262), Expect = 2e-23, Method: Composition-based stats. Identities = 58/299 (19%), Positives = 85/299 (28%), Gaps = 94/299 (31%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVT-----------GFDQAFTQEQYPFATEV-- 50 + + VTGA KGIG+ G V ++ + F V Sbjct: 14 TKRYAVVTGANKGIGFEICKQLASKGITVILASRDEKRGIEARERLIKELGSEFGDYVVS 73 Query: 51 --MDVADAAQVAQVCQRLLAETERLDALVNAAGI-------------------------- 82 +DVAD A VA + + + LD LVN AG+ Sbjct: 74 QQLDVADPASVAALVDFIKTKFGSLDILVNNAGLNGTYMEGDASVLNDYVEAEFKTFQSG 133 Query: 83 ------LRMGATDQL--SKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAA 134 AT +L + E ++ N G+ + + + ++ IV V+S + Sbjct: 134 AAKTEPYHPKATGRLVETVEHAKECIETNYYGSKRVTEALIPLLQQSDSPRIVNVSSTLS 193 Query: 135 HTP-------------------------------------------RIGMSAYGASKAAL 151 SAY SKAAL Sbjct: 194 SLVFQTNEWAKGVFSSEEGLTEEKLEEVLAEFLKDFIDGKQQEKQWPPHFSAYKVSKAAL 253 Query: 152 KSLALSVGLELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLG 210 + + + R N V PG T TD+ DAE G P G Sbjct: 254 NAYTRIIAKKYPSF--RINAVCPGYTKTDLSYGHGQFTDAEAAEAPVKLALLPQGGPSG 310 >2PTG-A nrPDB Length = 319 Score = 104 bits (260), Expect = 4e-23, Method: Composition-based stats. Identities = 40/191 (20%), Positives = 78/191 (40%), Gaps = 8/191 (4%) Query: 59 VAQVCQRLLAETERLDALVNAA--GILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMN 116 +++V + + A+ ++D LV++ G Q S++ + + + +L Q + Sbjct: 120 ISEVAEAVRADVGQIDILVHSLANGPEVTKPLLQTSRKGYLAAVSSSSYSFVSLLQHFLP 179 Query: 117 QFRRQRGGAIVTVASDAAHTPRIGMSA-YGASKAALKSLALSVGLELAG-SGVRCNVVSP 174 + GG+ + ++ A+ G ++KAAL+S ++ E VR N +S Sbjct: 180 LMKE--GGSALALSYIASEKVIPGYGGGMSSAKAALESDCRTLAFEAGRARAVRVNCISA 237 Query: 175 GSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHIT 234 G + + + D I + + PL K ++ LFL S LA +T Sbjct: 238 GPLKSRAASAIGKAGDKTF--IDLAIDYSEANAPLQKELESDDVGRAALFLLSPLARAVT 295 Query: 235 LQDIVVDGGST 245 + VD G Sbjct: 296 GATLYVDNGLH 306 >5WQO-A nrPDB Length = 234 Score = 103 bits (257), Expect = 9e-23, Method: Composition-based stats. Identities = 54/192 (28%), Positives = 75/192 (39%), Gaps = 17/192 (8%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQ---------AFTQEQYPFATEVMDVA 54 S NV + GA +GIG A AF++ GA+V + A + V Sbjct: 5 SMHNVLIVGASRGIGLGLADAFLQRGAQVFAVARRPQGSPGLQALAERAGERLQAVTGDL 64 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATD--QLSKEDWQQTFAVNVGGAFNLFQ 112 + A+ +L E R+D L+ AGI D ++ E Q F N L + Sbjct: 65 NQHDCAERIGEMLGE-RRIDRLIVNAGIYGPQQQDVAEIDAEQTAQLFLTNAIAPLRLAR 123 Query: 113 QTMNQFRRQRGGAIVTVASDAAHTP---RIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 R RGG + ++S A M YGASKAAL SL S E Sbjct: 124 ALSG--RVSRGGVVAFMSSQMASLALGLSATMPLYGASKAALNSLVRSWEGEFEELPFSL 181 Query: 170 NVVSPGSTDTDM 181 ++ PG T+M Sbjct: 182 LLLHPGWVRTEM 193 >3F4B-A nrPDB Length = 323 Score = 102 bits (255), Expect = 1e-22, Method: Composition-based stats. Identities = 37/207 (17%), Positives = 77/207 (37%), Gaps = 20/207 (9%) Query: 58 QVAQVCQRLLAETERLDALVNAA--GILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTM 115 + +V + + ++ LV++ G + S++ + + + +L + Sbjct: 106 SIEEVANLIYNKYGKISMLVHSLANGREVQKSLLDTSRDGYLDAISKSSYSLISLCKHFC 165 Query: 116 NQFRRQRGGAIVTVASDAAHTPRIGMSA-YGASKAALKSLALSVGLELA-GSGVRCNVVS 173 GG++V++ A+ G ++KAAL+S + L +R N +S Sbjct: 166 KFM--NSGGSVVSLTYQASQKVVPGYGGGMSSAKAALESDTRVLAYYLGRKYNIRINTIS 223 Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLG--------------IPLGKIARPQEIA 219 G + + ++ ++ + GE K PL K ++ Sbjct: 224 AGPLKSRAATAINKFNNNQKNNMNSSGETDKQNYSFIDYAIDYSEKYAPLKKKLLSTDVG 283 Query: 220 NTILFLASDLASHITLQDIVVDGGSTL 246 + FL S +S +T Q I VD G + Sbjct: 284 SVASFLLSKESSAVTGQTIYVDNGLNI 310 >1N5D-A nrPDB Length = 288 Score = 101 bits (252), Expect = 3e-22, Method: Composition-based stats. Identities = 48/234 (20%), Positives = 68/234 (29%), Gaps = 62/234 (26%) Query: 6 KNVWVTGAGKGIGYATALAF-----------VEAGAKVTGFDQAFTQEQYPFATEVMDVA 54 + VTGA KGIG+A A+ + E +D+ Sbjct: 5 RVALVTGANKGIGFAIVRDLCRQFAGDVVLTARDVARGQAAVKQLQAEGLSPRFHQLDII 64 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQ--TFAVNVGGAFNLFQ 112 D + +C L E LD LVN A I D + Q T N G N+ Sbjct: 65 DLQSIRALCDFLRKEYGGLDVLVNNAAIAF--QLDNPTPFHIQAELTMKTNFMGTRNVCT 122 Query: 113 QTMNQFRRQRGGAIVTVASDAAHTPRIGMSA----------------------------- 143 + + + Q G +V V+S S Sbjct: 123 ELLPLIKPQ--GRVVNVSSTEGVRALNECSPELQQKFKSETITEEELVGLMNKFVEDTKN 180 Query: 144 ------------YGASKAALKSLALSVGLEL----AGSGVRCNVVSPGSTDTDM 181 YG +K + L+ +L AG + N PG TDM Sbjct: 181 GVHRKEGWSDSTYGVTKIGVSVLSRIYARKLREQRAGDKILLNACCPGWVRTDM 234 >3BHI-A nrPDB Length = 276 Score = 99.1 bits (246), Expect = 1e-21, Method: Composition-based stats. Identities = 47/251 (18%), Positives = 68/251 (27%), Gaps = 58/251 (23%) Query: 7 NVWVTGAGKGIGYATALAFVE--AGAKVT---------GFDQAFTQEQYPFATEVMDVAD 55 VTG KGIG A +G V Q E +D+ D Sbjct: 6 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDD 65 Query: 56 AAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTM 115 + + L E LD LVN AGI A + T N G ++ + + Sbjct: 66 LQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCTELL 125 Query: 116 NQFRRQRGGAIVTVASDAAHTPRIG----------------------------------- 140 + Q G +V V+S + Sbjct: 126 PLIKPQ--GRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVH 183 Query: 141 ------MSAYGASKAALKSLALSVGLELAG----SGVRCNVVSPGSTDTDMQRTLWVSDD 190 SAYG +K + L+ +L+ + N PG TDM Sbjct: 184 QKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGPKATKSP 243 Query: 191 AEEQRIRGFGE 201 E + Sbjct: 244 EEGAETPVYLA 254 >1SNY-A nrPDB Length = 267 Score = 98.7 bits (245), Expect = 2e-21, Method: Composition-based stats. Identities = 38/203 (18%), Positives = 73/203 (35%), Gaps = 29/203 (14%) Query: 8 VWVTGAGKGIGYATALAFVE-----AGAKVTGFDQAFTQEQYPFA-------TEVMDVAD 55 + +TG +G+G A + T ++ +E A +D+ + Sbjct: 24 ILITGCNRGLGLGLVKALLNLPQPPQHLFTTCRNREQAKELEDLAKNHSNIHILEIDLRN 83 Query: 56 AAQVAQVCQRL--LAETERLDALVNAAGILRMGA-TDQLSKEDWQQTFAVNVGGAFNLFQ 112 ++ + + + + L+ L N AGI A + ++ T N L + Sbjct: 84 FDAYDKLVADIEGVTKDQGLNVLFNNAGIAPKSARITAVRSQELLDTLQTNTVVPIMLAK 143 Query: 113 QTMNQFRRQ-----------RGGAIVTVASDAAHTPR---IGMSAYGASKAALKSLALSV 158 + ++ AI+ ++S GM AY SK+AL + S+ Sbjct: 144 ACLPLLKKAAKANESQPMGVGRAAIINMSSILGSIQGNTDGGMYAYRTSKSALNAATKSL 203 Query: 159 GLELAGSGVRCNVVSPGSTDTDM 181 ++L + C + PG TDM Sbjct: 204 SVDLYPQRIMCVSLHPGWVKTDM 226 >3O26-A nrPDB Length = 311 Score = 95.3 bits (236), Expect = 2e-20, Method: Composition-based stats. Identities = 45/304 (14%), Positives = 75/304 (24%), Gaps = 90/304 (29%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFAT-----------EVMDVA 54 + VTG KGIG+ G V + T+ +DV Sbjct: 13 RCAVVTGGNKGIGFEICKQLSSNGIMVVLTCRDVTKGHEAVEKLKNSNHENVVFHQLDVT 72 Query: 55 DA-AQVAQVCQRLLAETERLDALVNAAGILRMG--------------------------- 86 D A ++ + + +LD LVN AG+ Sbjct: 73 DPIATMSSLADFIKTHFGKLDILVNNAGVAGFSVDADRFKAMISDIGEDSEELVKIYEKP 132 Query: 87 ---ATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAA--------- 134 + E ++ +N G ++ + + + IV V+S Sbjct: 133 EAQELMSETYELAEECLKINYNGVKSVTEVLIPLLQLSDSPRIVNVSSSTGSLKYVSNET 192 Query: 135 ---------------------------------HTPRIGM-SAYGASKAALKSLALSVGL 160 +AY SKA L + + Sbjct: 193 ALEILGDGDALTEERIDMVVNMLLKDFKENLIETNGWPSFGAAYTTSKACLNAYTRVLAN 252 Query: 161 ELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIAN 220 ++ N V PG T+M + E F P G + + Sbjct: 253 KIPKFQ--VNCVCPGLVKTEMNYGIGNYTAEEGAEHVVRIALFPDDGPSGFFY---DCSE 307 Query: 221 TILF 224 F Sbjct: 308 LSAF 311 >2O2Y-A nrPDB Length = 349 Score = 92.9 bits (230), Expect = 1e-19, Method: Composition-based stats. Identities = 43/254 (16%), Positives = 87/254 (34%), Gaps = 43/254 (16%) Query: 33 TGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRLLAETERLDALVN---AAGILRMGATD 89 FD A ++ + ++ + V + + +++ LV+ A Sbjct: 86 ASFDTANDIDEETKNNKRYNMLQNYTIEDVANLIHQKYGKINMLVHSLANA-KEVQKDLL 144 Query: 90 QLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSA-YGASK 148 S++ + + + +L + +N + Q +I+++ A+ G ++K Sbjct: 145 NTSRKGYLDALSKSSYSLISLCKYFVNIMKPQS--SIISLTYHASQKVVPGYGGGMSSAK 202 Query: 149 AALKSLALSVGLELAG-SGVRCNVVSPGSTDT--------------------------DM 181 AAL+S + L +R N +S G + D+ Sbjct: 203 AALESDTRVLAYHLGRNYNIRINTISAGPLKSRAATAINKLNNTYENNTNQNKNRNSHDV 262 Query: 182 QRTLWVSDDAEEQR---------IRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASH 232 + S + EE++ I E + PL + +I + FL S + Sbjct: 263 HNIMNNSGEKEEKKNSASQNYTFIDYAIEYSEKYAPLRQKLLSTDIGSVASFLLSRESRA 322 Query: 233 ITLQDIVVDGGSTL 246 IT Q I VD G + Sbjct: 323 ITGQTIYVDNGLNI 336 >5LCX-A nrPDB Length = 316 Score = 89.9 bits (222), Expect = 1e-18, Method: Composition-based stats. Identities = 52/299 (17%), Positives = 78/299 (26%), Gaps = 96/299 (32%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQ--------------EQYPFATEVM 51 + VTGA KGIG+ E G V + + + + Sbjct: 8 RYALVTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKELNVSENRLVFHQL 67 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLS------KEDWQQT------ 99 DV D A VA V + ++ +LD LVN AG+ + +S + D++ Sbjct: 68 DVTDLASVAAVAVFIKSKFGKLDILVNNAGVSGVEMVGDVSVFNEYIEADFKALQALEAG 127 Query: 100 -------------------------FAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAA 134 N G L Q + + IV V+S Sbjct: 128 AKEEPPFKPKANGEMIEKFEGAKDCVVTNYYGPKRLTQALIPLLQLSPSPRIVNVSSSFG 187 Query: 135 HTP-------------------------------------------RIGMSAYGASKAAL 151 +A SKAAL Sbjct: 188 SLLLLWNEWAKGVLGDEDRLTEERVDEVVEVFLKDIKEGKLEESQWPPHFAAERVSKAAL 247 Query: 152 KSLALSVGLELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLG 210 + + R N + PG TD+ AE ++ G P G Sbjct: 248 NAYTKIAAKKYPSF--RINAICPGYAKTDITFHAGPLSVAEAAQVPVKLALLPDGGPSG 304 >5TQV-A nrPDB Length = 233 Score = 85.2 bits (210), Expect = 2e-17, Method: Composition-based stats. Identities = 45/195 (23%), Positives = 67/195 (34%), Gaps = 14/195 (7%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQ----EQYPFATEVMDVADAAQVAQ 61 K V + GA +G+G + G V + +D+ Q+A Sbjct: 10 KTVLIVGASRGLGREFVRQYQRDGWNVIATARDDASLAALRALGAHAHALDITQPEQIAA 69 Query: 62 VCQRLLAETERLDALVNAAGILRMGA--TDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFR 119 + +L E RLD V +G+ + ++ +D+ NV G L + Sbjct: 70 LGWKLDGE--RLDVAVVVSGVYGPRTEGVETIASDDFDTVMHTNVRGPMQLLPILLPLVE 127 Query: 120 RQRGGAIVT---VASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGS 176 RG V + S + T G Y ASKAAL + L C + PG Sbjct: 128 DARGVLAVVSSRMGSISEATGTTGW-LYRASKAALNDVLRIAS--LQTRHAACISLHPGW 184 Query: 177 TDTDMQRTLWVSDDA 191 TDM D A Sbjct: 185 VRTDMGGAQAALDPA 199 >4Z3K-A nrPDB Length = 275 Score = 79.5 bits (195), Expect = 1e-15, Method: Composition-based stats. Identities = 48/220 (21%), Positives = 72/220 (32%), Gaps = 29/220 (13%) Query: 7 NVWVTGAGKGIGY------------ATALAFVEAGAKVT---GFDQAFTQEQYPFATEVM 51 +TGA +G G + L + + + Sbjct: 23 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 82 Query: 52 DVADAAQVAQVCQRLLA-----ETERLDALVNAAGILRM---GATDQLSKEDWQQTFAVN 103 D+ A + Q+ L +RL L+N AG L G D +A+N Sbjct: 83 DLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 141 Query: 104 VGGAFNLFQQTMNQFRRQRG--GAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLE 161 + L + F G +V ++S A P G + Y A KAA L + LE Sbjct: 142 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 201 Query: 162 LAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGE 201 VR +PG DTDM + L + +G E Sbjct: 202 --EPNVRVLNYAPGPLDTDM-QQLARETSVDPDMRKGLQE 238 >4HWK-A nrPDB Length = 288 Score = 79.5 bits (195), Expect = 1e-15, Method: Composition-based stats. Identities = 48/220 (21%), Positives = 72/220 (32%), Gaps = 29/220 (13%) Query: 7 NVWVTGAGKGIGY------------ATALAFVEAGAKVT---GFDQAFTQEQYPFATEVM 51 +TGA +G G + L + + + Sbjct: 36 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 95 Query: 52 DVADAAQVAQVCQRLLA-----ETERLDALVNAAGILRM---GATDQLSKEDWQQTFAVN 103 D+ A + Q+ L +RL L+N AG L G D +A+N Sbjct: 96 DLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 154 Query: 104 VGGAFNLFQQTMNQFRRQRG--GAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLE 161 + L + F G +V ++S A P G + Y A KAA L + LE Sbjct: 155 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 214 Query: 162 LAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGE 201 VR +PG DTDM + L + +G E Sbjct: 215 --EPNVRVLNYAPGPLDTDM-QQLARETSVDPDMRKGLQE 251 >1OAA-A nrPDB Length = 259 Score = 77.2 bits (189), Expect = 6e-15, Method: Composition-based stats. Identities = 48/214 (22%), Positives = 76/214 (35%), Gaps = 28/214 (13%) Query: 7 NVWVTGAGKGIGYATALAFVEA---GAKVTGFDQAFT------------QEQYPFATEVM 51 +TGA +G G A A G+ + ++ + Q Sbjct: 8 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAA 67 Query: 52 DVADAAQVAQVCQRLLA-----ETERLDALVNAAGILRM---GATDQLSKEDWQQTFAVN 103 D+ A V ++ + +RL L+N A L G + + +A+N Sbjct: 68 DLGTEAGVQRLLSAVRELPRPEGLQRL-LLINNAATLGDVSKGFLNVNDLAEVNNYWALN 126 Query: 104 VGGAFNLFQQTMNQFRRQRGGA--IVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLE 161 + L T+N F+ G + +V ++S A P G Y A KAA L + E Sbjct: 127 LTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAAE 186 Query: 162 LAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQR 195 VR +PG D DMQ+ + E R Sbjct: 187 --EPSVRVLSYAPGPLDNDMQQLARETSKDPELR 218 >3ORF-A nrPDB Length = 251 Score = 69.1 bits (168), Expect = 2e-12, Method: Composition-based stats. Identities = 40/183 (21%), Positives = 66/183 (36%), Gaps = 11/183 (6%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVAD--AAQVAQVC 63 KN+ V G +G F D + P A + D ++ V Sbjct: 23 KNILVLGGSGALGAEVVKFFKSKSWNTISIDF----RENPNADHSFTIKDSGEEEIKSVI 78 Query: 64 QRLLAETERLDALVNAAGILRMGATDQLS-KEDWQQTFAVNVGGAFNLFQQTMNQFRRQR 122 +++ +++ ++D V AAG G + + +N+ AF + Sbjct: 79 EKINSKSIKVDTFVCAAGGWSGGNASSDEFLKSVKGMIDMNLYSAFASAHIGAKLL--NQ 136 Query: 123 GGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELA--GSGVRCNVVSPGSTDTD 180 GG V + AA GM AYGA+KAA + + E +G + P + DT Sbjct: 137 GGLFVLTGASAALNRTSGMIAYGATKAATHHIIKDLASENGGLPAGSTSLGILPVTLDTP 196 Query: 181 MQR 183 R Sbjct: 197 TNR 199 >3SLK-A nrPDB Length = 795 Score = 64.1 bits (155), Expect = 5e-11, Method: Composition-based stats. Identities = 43/188 (22%), Positives = 64/188 (34%), Gaps = 37/188 (19%) Query: 7 NVWVTGAGKGIGYATALAF-----------------VEAGAKVTGFDQAFTQEQYPFATE 49 V VTG +G A +GA T + + Sbjct: 532 TVLVTGGTGALGAEVARHLVIERGVRNLVLVSRRGPAASGA--AELVAQLTAYGAEVSLQ 589 Query: 50 VMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 DVAD +A+V + E L A+V+AAG+L G ++ L+ E Q V GA N Sbjct: 590 ACDVADRETLAKVLASIPDEH-PLTAVVHAAGVLDDGVSESLTVERLDQVLRPKVDGARN 648 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSL----------ALSVG 159 L + A+V +S + G Y A+ + L +L S+ Sbjct: 649 LLELIDPDV------ALVLFSSVSGVLGSGGQGNYAAANSFLDALAQQRQSRGLPTRSLA 702 Query: 160 -LELAGSG 166 A G Sbjct: 703 WGPWAEHG 710 >2PK3-A nrPDB Length = 321 Score = 62.9 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 47/261 (18%), Positives = 87/261 (33%), Gaps = 47/261 (18%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRL 66 +TG +G A E +V G + + +D+ D+ +V +V + Sbjct: 14 RALITGVAGFVGKYLANHLTEQNVEVFGTSRNNEAKLPNVEMISLDIMDSQRVKKVISDI 73 Query: 67 LAETERLDALVNAAGILRMGATDQLSKEDW---QQTFAVNVGGAFNLFQQTMNQFRRQRG 123 + D + + A + + W + TF+ NV G ++ + R Sbjct: 74 -----KPDYIFHLAAKSSVK-------DSWLNKKGTFSTNVFGTLHVLDAVRDSNLDCR- 120 Query: 124 GAIVTVAS-------------DAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGV--- 167 I+T+ S + MS YG SKA++ LA + Sbjct: 121 --ILTIGSSEEYGMILPEESPVSEENQLRPMSPYGVSKASVGMLARQYVKAYGMDIIHTR 178 Query: 168 RCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANT-----I 222 N + PG Q +V+ D +Q + E+ + I +G + ++ + Sbjct: 179 TFNHIGPG------QSLGFVTQDFAKQIVDIEMEKQEPIIKVGNLEAVRDFTDVRDIVQA 232 Query: 223 LFLASDLASHITLQDIVVDGG 243 +L S T V G Sbjct: 233 YWLLSQYGK--TGDVYNVCSG 251 >1OOE-A nrPDB Length = 236 Score = 61.7 bits (149), Expect = 2e-10, Method: Composition-based stats. Identities = 37/188 (19%), Positives = 64/188 (34%), Gaps = 14/188 (7%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVC 63 SGK + V G +G A F + G V D + + + Q + Sbjct: 3 SGKVI-VYGGKGALGSAILEFFKKNGYTVLNIDLSANDQADSNILVDGNKNWTEQEQSIL 61 Query: 64 QRLLAETER--LDALVNAAGILRMGATDQLSKEDW----QQTFAVNVGGAFNLFQQTMNQ 117 ++ + + +D + AG G+ S +D+ +V + + Sbjct: 62 EQTASSLQGSQVDGVFCVAGGWAGGSA---SSKDFVKNADLMIKQSVWSSAIAAKLATTH 118 Query: 118 FRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGL--ELAGSGVRCNVVSPG 175 + GG + + AA P M YG +KAA+ L S+ + P Sbjct: 119 LKP--GGLLQLTGAAAAMGPTPSMIGYGMAKAAVHHLTSSLAAKDSGLPDNSAVLTIMPV 176 Query: 176 STDTDMQR 183 + DT M R Sbjct: 177 TLDTPMNR 184 >1DIR-A nrPDB Length = 241 Score = 60.6 bits (146), Expect = 6e-10, Method: Composition-based stats. Identities = 42/194 (21%), Positives = 61/194 (31%), Gaps = 15/194 (7%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQR 65 + V V G +G AF V D +E M + Q QV Sbjct: 8 RRVLVYGGRGALGSRCVQAFRARNWWVASIDVVENEEASASVIVKMTDSFTEQADQVTAE 67 Query: 66 LLAETE--RLDALVNAAGILRMGATDQLSKED-----WQQTFAVNVGGAFNLFQQTMNQF 118 + ++DA++ AG G S W+Q+ + Sbjct: 68 VGKLLGDQKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSIWTSTIS----SHLATKHL 123 Query: 119 RRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVG--LELAGSGVRCNVVSPGS 176 + GG + + AA GM YG +K A+ L S+ SG V P + Sbjct: 124 KE--GGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKNSGMPSGAAAIAVLPVT 181 Query: 177 TDTDMQRTLWVSDD 190 DT M R D Sbjct: 182 LDTPMNRKSMPEAD 195 >3RFT-A nrPDB Length = 267 Score = 57.1 bits (137), Expect = 7e-09, Method: Composition-based stats. Identities = 33/167 (19%), Positives = 52/167 (31%), Gaps = 32/167 (19%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV-MDVADAAQVAQ 61 + K + VTGA +G + D + P V D+ADA V Sbjct: 1 MAMKRLLVTGAAGQLGRVMRERLAPMAEILRLADLSPLDPAGPNEECVQCDLADANAVNA 60 Query: 62 VCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQ 121 + D +V+ GI ++Q N+ G +NL++ R Sbjct: 61 MVA-------GCDGIVHLGGISVEKP--------FEQILQGNIIGLYNLYEAA----RAH 101 Query: 122 RGGAIVTVASDAAHTPRIGM------------SAYGASKAALKSLAL 156 IV +S+ YG SK ++LA Sbjct: 102 GQPRIVFASSNHTIGYYPQTERLGPDVPARPDGLYGVSKCFGENLAR 148 >4LIS-A nrPDB Length = 371 Score = 56.4 bits (135), Expect = 1e-08, Method: Composition-based stats. Identities = 35/171 (20%), Positives = 58/171 (33%), Gaps = 38/171 (22%) Query: 8 VWVTGAGKGIGYATALAFVEAGAKVTGFD-----------QAFTQEQYPFATEVMDVADA 56 V VTG IG T LA +EAG KV D + +DV D Sbjct: 6 VLVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELISGKKAEFAQLDVTDE 65 Query: 57 AQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMN 116 A ++ +D++++ A + +G + + + + VNV G + Sbjct: 66 A----AFDKVFEAHPDIDSVIHFAALKAVGESGEKPLD----YYHVNVYGTI----CLLR 113 Query: 117 QFRRQRGGAIVTVASDAAHT---------------PRIGMSAYGASKAALK 152 R IV +S + P + YG +K A++ Sbjct: 114 SMVRHNVTNIVFSSSATVYGDATRFPDMIPIPEHCPLGPTNPYGNTKFAIE 164 >1VL0-A nrPDB Length = 292 Score = 52.5 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 24/163 (14%), Positives = 51/163 (31%), Gaps = 36/163 (22%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRL 66 + +TGA +G +V P + +D+ + V + Sbjct: 14 KILITGANGQLGREIQKQLKGKNVEVI-----------PTDVQDLDITNVLAVNKFFNE- 61 Query: 67 LAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAI 126 ++ + ++N A +E + + +N G NL + G I Sbjct: 62 ----KKPNVVINCAAHT----AVDKCEEQYDLAYKINAIGPKNLAAAAYSV-----GAEI 108 Query: 127 VTVASDAAHTPRI-----------GMSAYGASKAALKSLALSV 158 V +++D SAYG +K ++ ++ Sbjct: 109 VQISTDYVFDGEAKEPITEFDEVNPQSAYGKTKLEGENFVKAL 151 >2Q1W-A nrPDB Length = 333 Score = 50.6 bits (120), Expect = 7e-07, Method: Composition-based stats. Identities = 45/195 (23%), Positives = 66/195 (33%), Gaps = 36/195 (18%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV------MDVADAAQV 59 K V++TG IG A +E G KV G D T + +AD A V Sbjct: 22 KKVFITGICGQIGSHIAELLLERGDKVVGIDNFATGRREHLKDHPNLTFVEGSIADHALV 81 Query: 60 AQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFR 119 Q+ L + DA+V+ A + +DW N G N+ Q + Sbjct: 82 NQLIGDL-----QPDAVVHTAASYKD-------PDDWYNDTLTNCVGGSNVVQAA----K 125 Query: 120 RQRGGAIVT--VASDAAHTP-----------RIGMSAYGASKAALKSLALSVGLELAGSG 166 + G V A P S+Y SK+A + GL+ Sbjct: 126 KNNVGRFVYFQTALCYGVKPIQQPVRLDHPRNPANSSYAISKSANEDYLEYSGLDFVTFR 185 Query: 167 VRCNVVSPGSTDTDM 181 + NVV P + + Sbjct: 186 L-ANVVGPRNVSGPL 199 >3SC6-A nrPDB Length = 287 Score = 49.0 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 30/163 (18%), Positives = 59/163 (36%), Gaps = 36/163 (22%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRL 66 V +TGA +G + YPF +++D+ + +QV QV Q + Sbjct: 7 RVIITGANGQLGKQLQEEL-----------NPEEYDIYPFDKKLLDITNISQVQQVVQEI 55 Query: 67 LAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAI 126 R +++ A ++ ++ + +N GA N+ +Q G + Sbjct: 56 -----RPHIIIHCAAYTKVDQAEKER----DLAYVINAIGARNV--AVASQLV---GAKL 101 Query: 127 VTVASDAAHTP-----------RIGMSAYGASKAALKSLALSV 158 V +++D ++ YGASK A + + Sbjct: 102 VYISTDYVFQGDRPEGYDEFHNPAPINIYGASKYAGEQFVKEL 144 >1UDA-A nrPDB Length = 338 Score = 46.3 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 29/165 (17%), Positives = 50/165 (30%), Gaps = 36/165 (21%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFAT-----------EVMDVAD 55 V VTG IG T + ++ G V D ++ D+ + Sbjct: 2 RVLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVIERLGGKHPTFVEGDIRN 61 Query: 56 AAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTM 115 A + ++ +D +++ AG+ +G + Q E + NV G L Sbjct: 62 EALMTEIL-----HDHAIDTVIHFAGLKAVGESVQKPLEYYDN----NVNGTLRLISA-- 110 Query: 116 NQFRRQRGGAIVTVASDAAHTPRI------------GMSAYGASK 148 R + +S + S YG SK Sbjct: 111 --MRAANVKNFIFSSSATVYGDNPKIPYVESFPTGTPQSPYGKSK 153 >1Z45-A nrPDB Length = 699 Score = 45.6 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 30/175 (17%), Positives = 61/175 (34%), Gaps = 39/175 (22%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFAT-----------EVMDVA 54 K V VTG IG T + +E G D A +D+ Sbjct: 12 KIVLVTGGAGYIGSHTVVELIENGYDCVVADNLSNSTYDSVARLEVLTKHHIPFYEVDLC 71 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 D + +V + ++D++++ AG+ +G + Q+ + + N+ G L Sbjct: 72 DRKGLEKVFKEY-----KIDSVIHFAGLKAVGESTQIPL----RYYHNNILGTVVL---- 118 Query: 115 MNQFRRQRGGAIVTVASDAAHT---------------PRIGMSAYGASKAALKSL 154 + ++ V +S + P + YG +K A++++ Sbjct: 119 LELMQQYNVSKFVFSSSATVYGDATRFPNMIPIPEECPLGPTNPYGHTKYAIENI 173 >2NNL-D nrPDB Length = 337 Score = 45.2 bits (106), Expect = 3e-05, Method: Composition-based stats. Identities = 32/251 (12%), Positives = 71/251 (28%), Gaps = 29/251 (11%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRL 66 V VTGA IG + +E G V + T ++D+ A + + Sbjct: 7 TVCVTGASGFIGSWLVMRLLERGYTVRATVRDPT--NVKKVKHLLDLPKAETHLTLWKAD 64 Query: 67 LAETERLDALV-NAAGILRMGATDQLSKED-WQQTFAVNVGGAFNLFQQTMNQFRRQRGG 124 LA+ D + G+ + +D + + G + + + Sbjct: 65 LADEGSFDEAIKGCTGVFHVATPMDFESKDPENEVIKPTIEGMLGIMKSCAAAKTVR--- 121 Query: 125 AIVTVASDAAHTPRIGM-SAY----------GASK---AALKSLALSVGLELA-----GS 165 +V +S + Y +K A + ++ ++ + A + Sbjct: 122 RLVFTSSAGTVNIQEHQLPVYDESCWSDMEFCRAKKMTAWMYFVSKTLAEQAAWKYAKEN 181 Query: 166 GVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFL 225 + + P + E I G+ ++ N ++L Sbjct: 182 NIDFITIIPTLVVGPFIMSSMPPSLITALSPITGNEAHYSIIRQGQFVHLDDLCNAHIYL 241 Query: 226 ASD---LASHI 233 + +I Sbjct: 242 FENPKAEGRYI 252 >6BWL-A nrPDB Length = 328 Score = 44.8 bits (105), Expect = 4e-05, Method: Composition-based stats. Identities = 47/278 (16%), Positives = 82/278 (29%), Gaps = 71/278 (25%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQ----------AFTQEQYPFATEVMDVADA 56 + VTG IG ++ +V D F + D+ D Sbjct: 2 KILVTGGAGFIGRWVVKRLLQDKHEVWILDNLANSTTANITEFAHDLNLKQCIQGDIKDK 61 Query: 57 AQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMN 116 VAQ+ + D + A + + S +D + TF + G FNL +Q +N Sbjct: 62 KLVAQLFEN-----NSFDLCYHLAASINVQD----SIDDARATFENDTIGTFNLLEQCLN 112 Query: 117 Q----------FRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALS--VGLELAG 164 + + + P S Y SK A +++ LS +L Sbjct: 113 YDVKMVFMSTCMVYDKAT---NIQGISELDPIKPASPYAGSKIAAENMVLSYYYAYKLPV 169 Query: 165 SGVR-CNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIAR--------- 214 +R N P + E + F +PL Sbjct: 170 VVIRPFNTYGP-----------FQKTGGEGGVVAIFINNKLDNVPLNIYGDGKQTRDLLY 218 Query: 215 PQEIANTILFLASDLASHI-----------TLQDIVVD 241 ++ A+ ++ A + T QDI ++ Sbjct: 219 VEDCADFVV-----AAGYSAKANGHIINAGTGQDISIN 251 >1RKX-A nrPDB Length = 357 Score = 44.4 bits (104), Expect = 4e-05, Method: Composition-based stats. Identities = 39/203 (19%), Positives = 64/203 (31%), Gaps = 43/203 (21%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAF---------TQEQYPFATEVMDVA 54 GK V+VTG G +L GA V G+ + +E+ D+ Sbjct: 8 QGKRVFVTGHTGFKGGWLSLWLQTMGATVKGYSLTAPTVPSLFETARVADGMQSEIGDIR 67 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 D ++ + + E + + A +LS + +T++ NV G L + Sbjct: 68 DQNKLLESIREFQPE-----IVFHMAA----QPLVRLSYSEPVETYSTNVMGTVYLLEA- 117 Query: 115 MNQFRRQRGG--AIVTVASDAAH------------TPRIGMSAYGASKAALKSLALSVGL 160 R GG A+V + SD + G Y SK + + S Sbjct: 118 ----IRHVGGVKAVVNITSDKCYDNKEWIWGYRENEAMGGYDPYSNSKGCAELVTSSYRN 173 Query: 161 ------ELAGSGVRCNVVSPGST 177 G V G+ Sbjct: 174 SFFNPANYGQHGTAVATVRAGNV 196 >4G5H-A nrPDB Length = 363 Score = 44.0 bits (103), Expect = 6e-05, Method: Composition-based stats. Identities = 31/161 (19%), Positives = 66/161 (40%), Gaps = 27/161 (16%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAK-VTGFDQAFTQE--------QYPFATEVM 51 M F K + +TG G A F+++ K + F + ++ + Sbjct: 21 MGFDDKILLITGGTGSFGNAVMKRFLDSNIKEIRIFSRDEKKQDDIRKKYNNSKLKFYIG 80 Query: 52 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 DV D+ V + +D + +AA + ++ + + E + N+ G N+ Sbjct: 81 DVRDSQSVETAMRD-------VDYVFHAAALKQVPSCEFFPVEAVK----TNIIGTENVL 129 Query: 112 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALK 152 Q ++Q ++ ++ +++D A P +A G SKA ++ Sbjct: 130 QSAIHQNVKK----VICLSTDKAAYPI---NAMGISKAMME 163 >2GN9-A nrPDB Length = 344 Score = 44.0 bits (103), Expect = 6e-05, Method: Composition-based stats. Identities = 29/149 (19%), Positives = 53/149 (35%), Gaps = 14/149 (9%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVE-AGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQ 61 + + +TG G ++ AK +Q A E D + Sbjct: 19 LDNQTILITGGTGSFGKCFVRKVLDTTNAKKIIVYSRDELKQSEMAMEFNDPRMRFFIGD 78 Query: 62 V--CQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFR 119 V +RL E +D ++AA + + + E N+ GA N+ + Sbjct: 79 VRDLERLNYALEGVDICIHAAALKHVPIAEYNPLE----CIKTNIMGASNVINACLKNAI 134 Query: 120 RQRGGAIVTVASDAAHTPRIGMSAYGASK 148 Q ++ +++D A P + YGA+K Sbjct: 135 SQ----VIALSTDKAANPI---NLYGATK 156 >1WVG-A nrPDB Length = 359 Score = 42.5 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 35/169 (20%), Positives = 58/169 (34%), Gaps = 37/169 (21%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQ---------AFTQEQYPFATEVMDVA 54 GK V+VTG G +L E GA V G+ + + + D+ Sbjct: 8 QGKRVFVTGHTGFKGSWLSLWLTEMGAIVKGYALDAPTVPSLFEIVRLNDLMESHIGDIR 67 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 D ++ + + + + A +LS E +T++ NV G +L + Sbjct: 68 DFEKLRSSIAEF-----KPEIVFHMAA----QPLVRLSYEQPIKTYSTNVMGTVHLLETV 118 Query: 115 MNQFRRQRGG--AIVTVASDAAH------------TPRIGMSAYGASKA 149 +Q G A+V + SD + P G Y SK Sbjct: 119 -----KQVGNIKAVVNITSDKCYDNREWVWGYRENEPMGGYDPYSNSKG 162 >1I3M-A nrPDB Length = 348 Score = 41.7 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 33/182 (18%), Positives = 58/182 (31%), Gaps = 44/182 (24%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFD-----------------QAFTQEQYPFATE 49 V VTG IG T L +EAG D + E Sbjct: 4 KVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFE 63 Query: 50 VMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 MD+ D + ++ ++ A+++ AG+ MG + Q + + VN+ G Sbjct: 64 EMDILDQGALQRLFKKY-----SFMAVIHFAGLKAMGESVQKPLD----YYRVNLTGTIQ 114 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGM-------------SAYGASKAALKSLAL 156 L + + +V +S A + YG SK ++ + Sbjct: 115 L----LEIMKAHGVKNLVF-SSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIR 169 Query: 157 SV 158 + Sbjct: 170 DL 171 >1BXK-A nrPDB Length = 355 Score = 41.7 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 31/182 (17%), Positives = 58/182 (31%), Gaps = 38/182 (20%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAK-VTGFDQ----------AFTQEQYPFATEVMDVA 54 + + +TG IG A + + V D+ A + FA E +D+ Sbjct: 2 RKILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSLAPVAQSERFAFEKVDIC 61 Query: 55 DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 D A++A+V + D +++ A + + N+ G + L + Sbjct: 62 DRAELARVFTE-----HQPDCVMHLAAESHVDRSIDGP----AAFIETNIVGTYTLLEAA 112 Query: 115 MNQF---RRQRGGAI----VTVASDAA-----------HTPRIGMSAYGASKAALKSLAL 156 + + A ++ TP S Y ASKA+ L Sbjct: 113 RAYWNALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPYSASKASSDHLVR 172 Query: 157 SV 158 + Sbjct: 173 AW 174 >1ZZE-A nrPDB Length = 342 Score = 40.9 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 24/139 (17%), Positives = 52/139 (37%), Gaps = 6/139 (4%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVC 63 G V VTGA + +E G KV G ++ ++ + D + Sbjct: 10 EGSLVLVTGANGFVASHVVEQLLEHGYKVRGTARSASKLAN--LQKRWDAKYPGRFETAV 67 Query: 64 QRLLAETERLDALV-NAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQR 122 + + D ++ AAG+ + + S + + + +GG N + +R Sbjct: 68 VEDMLKQGAYDEVIKGAAGVAHIASVVSFSNK-YDEVVTPAIGGTLNALRAAAATPSVKR 126 Query: 123 GGAIVTVASDAAHTPRIGM 141 ++T ++ +A P+ + Sbjct: 127 F--VLTSSTVSALIPKPNV 143 >3SXP-A nrPDB Length = 362 Score = 40.6 bits (94), Expect = 7e-04, Method: Composition-based stats. Identities = 33/203 (16%), Positives = 63/203 (31%), Gaps = 47/203 (23%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAG--AKVTGFDQAFTQE----------------- 42 + + + +TG +G A F E AKV D+ + Sbjct: 7 ELENQTILITGGAGFVGSNLAFHFQENHPKAKVVVLDKFRSNTLFSNNRPSSLGHFKNLI 66 Query: 43 QYPFATEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAV 102 + D+ + + ++ ++L D L + A + +Q + Sbjct: 67 GFKGEVIAADINNPLDLRRL-EKL-----HFDYLFHQAAVSDTTMLNQ------ELVMKT 114 Query: 103 NVGGAFNLFQQTMNQFRRQRGGAIVTVAS--DAAHTPRIGM--------SAYGASKAALK 152 N NL + R + ++ +S +T + + YG SK + Sbjct: 115 NYQAFLNLLEIA-----RSKKAKVIYASSAGVYGNTKAPNVVGKNESPENVYGFSKLCMD 169 Query: 153 SLALSVGLELAGSGVR-CNVVSP 174 LS + G+R NV P Sbjct: 170 EFVLSHSNDNVQVGLRYFNVYGP 192 >5INT-A nrPDB Length = 220 Score = 40.6 bits (94), Expect = 7e-04, Method: Composition-based stats. Identities = 17/101 (16%), Positives = 31/101 (30%), Gaps = 20/101 (19%) Query: 3 FSGKNVWVTGA---------------GKG-IGYATALAFVEAGAKVTGFDQAFTQEQYPF 46 GK + +T G +GYA A V GA+V T P Sbjct: 4 LQGKRILITAGPTREKIDPVRFMTNFSSGKMGYAIAEVAVNLGAEVILVS-GPTALNPPL 62 Query: 47 ATEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGA 87 + V + + ++ + +D ++ A + Sbjct: 63 HVTTVQV---ESAQDMLEAVIQHYQNVDVVIKTAAVADYRP 100 >3ENK-A nrPDB Length = 341 Score = 39.8 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 26/76 (34%), Gaps = 12/76 (15%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFAT-----------E 49 M G + VTG IG TA+ + G V D ++ A Sbjct: 2 MSTKG-TILVTGGAGYIGSHTAVELLAHGYDVVIADNLVNSKREAIARIEKITGKTPAFH 60 Query: 50 VMDVADAAQVAQVCQR 65 DV+D +A++ Sbjct: 61 ETDVSDERALARIFDA 76 >1GY8-A nrPDB Length = 397 Score = 39.4 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 36/208 (17%), Positives = 54/208 (25%), Gaps = 60/208 (28%) Query: 7 NVWVTGAGKGIGYATALAFVEA-GAKVTGFD-------------------QAFTQEQYP- 45 V V G IG A + V D + Q P Sbjct: 4 RVLVCGGAGYIGSHFVRALLRDTNHSVVIVDSLVGTHGKSDHVETRENVARKLQQSDGPK 63 Query: 46 -------FATEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQ 98 A EV DV + + +DA+V+ L +G + + + Sbjct: 64 PPWADRYAALEVGDVRNE----DFLNGVFTRHGPIDAVVHMCAFLAVGESVRDPL----K 115 Query: 99 TFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGM----------------- 141 + NV G L Q + I+ +S AA M Sbjct: 116 YYDNNVVGILRLLQA----MLLHKCDKIIF-SSSAAIFGNPTMGSVSTNAEPIDINAKKS 170 Query: 142 --SAYGASKAALKSLALSVGLELAGSGV 167 S YG SK + + G+ Sbjct: 171 PESPYGESKLIAERMIRDCAEAYGIKGI 198 >4KTT-E nrPDB Length = 327 Score = 38.2 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 25/158 (15%), Positives = 53/158 (33%), Gaps = 28/158 (17%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVA 60 ++ + V VTGA +G A F + G + ++ E +++ D+ V Sbjct: 17 VNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKF----EQVNLLDSNAVH 72 Query: 61 QVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRR 120 + +V+ A R + + +NV + NL ++ Sbjct: 73 HIIHDFQPH-----VIVHCAAERRP----DVVENQPDAASQLNVDASGNLAKEA-----A 118 Query: 121 QRGGAIVTVASDAAHTP----------RIGMSAYGASK 148 G ++ ++SD ++ YG +K Sbjct: 119 AVGAFLIYISSDYVFDGTNPPYREEDIPAPLNLYGKTK 156 >2PZM-A nrPDB Length = 330 Score = 37.9 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 26/166 (15%), Positives = 56/166 (33%), Gaps = 35/166 (21%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQY------PFATEVMDVADAAQVA 60 + +TG +G ++ G ++ D T ++ + V DA + Sbjct: 22 RILITGGAGCLGSNLIEHWLPQGHEILVIDNFATGKREVLPPVAGLSVIEGSVTDAGLLE 81 Query: 61 QVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRR 120 + +V++A + +DW + A NV G+ N+ + + Sbjct: 82 RAFDSFKPTH-----VVHSAAAYKD-------PDDWAEDAATNVQGSINVAKAASKAGVK 129 Query: 121 Q-----------RGGAI-VTVASDAAHTPRIGMSAYGASKAALKSL 154 + R + + + S P ++YG SK A ++ Sbjct: 130 RLLNFQTALCYGRPATVPIPIDS-----PTAPFTSYGISKTAGEAF 170 >4KDR-A nrPDB Length = 223 Score = 37.5 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 24/75 (32%), Gaps = 4/75 (5%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQV 62 GK V G G GI A + GA VTG D F Q + V + Sbjct: 61 LFGKKVLDVGCGGGI---LAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQET 117 Query: 63 CQR-LLAETERLDAL 76 + + D + Sbjct: 118 VEEHAAKHAGQYDVV 132 >4KDC-A nrPDB Length = 246 Score = 37.5 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 24/75 (32%), Gaps = 4/75 (5%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQV 62 GK V G G GI A + GA VTG D F Q + V + Sbjct: 61 LFGKKVLDVGCGGGI---LAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQET 117 Query: 63 CQR-LLAETERLDAL 76 + + D + Sbjct: 118 VEEHAAKHAGQYDVV 132 >1KEU-A nrPDB Length = 361 Score = 37.5 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 27/202 (13%), Positives = 58/202 (28%), Gaps = 46/202 (22%) Query: 7 NVWVTGAGKGIGYATALAFVEAG-AKVTGFDQ----------AFTQEQYPFATEVMDVAD 55 + +TG IG A ++ V D+ + E + E D+ D Sbjct: 2 KILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISESNRYNFEHADICD 61 Query: 56 AAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTM 115 +A++ ++ ++ + DA+++ A + + N+ G + L + Sbjct: 62 SAEITRIFEQY-----QPDAVMHLAAESHVDRSITGP----AAFIETNIVGTYALLEVAR 112 Query: 116 NQFRR---QRGGAI----VTVASDAAHTPRI-------------------GMSAYGASKA 149 + + ++ P S Y ASKA Sbjct: 113 KYWSALGEDKKNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTAYAPSSPYSASKA 172 Query: 150 ALKSLALSVGLELAGSGVRCNV 171 + L + + N Sbjct: 173 SSDHLVRAWRRTYGLPTIVTNC 194 >6DEB-A nrPDB Length = 285 Score = 37.1 bits (85), Expect = 0.008, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 37/99 (37%), Gaps = 4/99 (4%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVA 60 +D GK+ + GA +G A + AGA V+ + + A V Sbjct: 156 IDLEGKDAVIIGASNIVGRPMATMLLNAGATVSVCHIKTKDLSLYTRQADLIIVAAGCVN 215 Query: 61 QVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQT 99 + ++ E +V GI R+ + + D+++ Sbjct: 216 LLRSDMVKEG----VIVVDVGINRLESGKIVGDVDFEEV 250 >3WMX-A nrPDB Length = 358 Score = 36.7 bits (84), Expect = 0.009, Method: Composition-based stats. Identities = 41/194 (21%), Positives = 64/194 (32%), Gaps = 41/194 (21%) Query: 4 SGK-NVWVTGAGKGIGYATALAFVEA-G-AKVTGFDQAFTQEQYPFATEVMDVADAAQVA 60 +GK + + GA IG ALA E G V D T E+++ D ++A Sbjct: 23 AGKPKILIVGANGQIGSELALALAERYGRTNVITSDVVPTGRHVHLTHEMLNATDRGELA 82 Query: 61 QVCQRLLAETERLDALVNAAGILRM----GATDQLSKEDWQQTFAVNVGGAFNLFQQTMN 116 V +R GI ++ A ++ Q + +N+ N+ + Sbjct: 83 TVVER--------------HGITQVYLLAAALSATGEKAPQWAWNLNMTSLLNVLELA-- 126 Query: 117 QFRRQRGGAIVTVASDAAHTP------------RIGMSAYGASKAALKSLALSVGLELAG 164 R+ + +S AA P + YG SK A + A Sbjct: 127 --RQTGLERVFWPSSIAAFGPTTPAGQTPQKTVMEPTTVYGISKQAGEGWCRWY---HAN 181 Query: 165 SGVRCNVVS-PGST 177 GV V PG Sbjct: 182 HGVDVRSVRYPGLI 195 >5B6K-A nrPDB Length = 366 Score = 36.7 bits (84), Expect = 0.010, Method: Composition-based stats. Identities = 24/143 (16%), Positives = 52/143 (36%), Gaps = 25/143 (17%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQ---------EQYPFATEVM-DVADA 56 V+V+GA I ++ KV G ++ + + F E++ D++D Sbjct: 23 TVFVSGATGFIAQHVVRQLLDQNYKVIGSVRSAEKGDHLKNVIFKGGDFNYEIVKDISDP 82 Query: 57 AQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMN 116 + + + D V +L + + D ++ + A N + + Sbjct: 83 ----TAFDHVFEKHGK-DIKV----VLHTASPFHFNTTDIEKDL---LIPAVNGTKGILE 130 Query: 117 QFRR---QRGGAIVTVASDAAHT 136 ++ Q +V +S AA+T Sbjct: 131 SIKKYAAQTVERVVVTSSFAANT 153 >4EJ0-A nrPDB Length = 342 Score = 36.3 bits (83), Expect = 0.011, Method: Composition-based stats. Identities = 26/154 (16%), Positives = 47/154 (30%), Gaps = 22/154 (14%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQR- 65 + VTGA IG A E G T+ ++ D + +R Sbjct: 14 TLIVTGAAGFIGANLVKALNERGETRIIAVDNLTRADKFKNLVDCEIDDYLDKTEFVERF 73 Query: 66 LLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGA 125 + ++ A+ + GA + D + N F + ++ Q G Sbjct: 74 ARGDFGKVRAVFH------EGACSDTMETDGRYMMDNN----FRYSRAVLDACLAQ-GAQ 122 Query: 126 IVTVASDAAHTPR----------IGMSAYGASKA 149 + +S A + ++ YG SK Sbjct: 123 FLYASSAAIYGGSSRFVEEREVEAPLNVYGYSKF 156 >4J2O-A nrPDB Length = 363 Score = 35.9 bits (82), Expect = 0.016, Method: Composition-based stats. Identities = 31/161 (19%), Positives = 59/161 (36%), Gaps = 31/161 (19%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAK-VTGFDQAFTQE--------QYPFATEVMDV 53 F K + +TG G A F+E K + F + ++ + DV Sbjct: 21 FKDKVLLITGGTGSFGNAVLKRFLETDIKEIRIFSRDEKKQDDMRKKYHSAKLKFYIGDV 80 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQ--QTFAVNVGGAFNLF 111 D + + +D + +AA A Q+ ++ + NV G N+ Sbjct: 81 RDYNSILNATR-------GVDYIYHAA------ALKQVPSCEFHPMEAVKTNVLGTENVL 127 Query: 112 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALK 152 + + + +V +++D A P +A G SKA ++ Sbjct: 128 EAAI----QNHVKRVVCLSTDKAVYPI---NAMGISKAMME 161 >2Z95-A nrPDB Length = 345 Score = 35.9 bits (82), Expect = 0.016, Method: Composition-based stats. Identities = 13/40 (32%), Positives = 19/40 (47%), Gaps = 2/40 (5%) Query: 3 FSGKNVWVTGAGKGI-GYATALAFVEAGAKVTGFDQAFTQ 41 SGK +TG +G G A +E G +V G D+ + Sbjct: 1 MSGKRALITGI-RGQDGAYLAKLLLEKGYEVYGADRRSGE 39 >3BIC-A nrPDB Length = 762 Score = 35.9 bits (82), Expect = 0.018, Method: Composition-based stats. Identities = 21/106 (19%), Positives = 34/106 (32%), Gaps = 18/106 (16%) Query: 12 GAGKGIGYATALAFVEAGAKVTG-----FDQAFTQEQYPFATEVMDVADAAQ-VAQVCQR 65 G +G A F + G V + Q+ + V+ A + Sbjct: 616 GHDRG-AKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLAAGHKTLVPE 674 Query: 66 LLAET---ERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAF 108 L+ E R D LV G+ + +D++ F V V F Sbjct: 675 LIKELNSLGRPDILVMCGGV--------IPPQDYEFLFEVGVSNVF 712 >2HUN-A nrPDB Length = 336 Score = 35.5 bits (81), Expect = 0.020, Method: Composition-based stats. Identities = 30/173 (17%), Positives = 56/173 (32%), Gaps = 35/173 (20%) Query: 9 WVTGAGKGIGYATALAFVEAG--AKVTGFDQ----------AFTQEQYPFATEVMDVADA 56 VTG IG +E +V D+ ++ + DVAD Sbjct: 7 LVTGGMGFIGSNFIRYILEKHPDWEVINIDKLGYGSNPANLKDLEDDPRYTFVKGDVADY 66 Query: 57 AQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMN 116 V ++ + ++D +V+ A + + S E + NV G + L + Sbjct: 67 ELVKELVR-------KVDGVVHLAAESHVDRSIS-SPEIF---LHSNVIGTYTLLESIRR 115 Query: 117 QFRRQRGGAI--------VTVASDAAHTPRIGMSAYGASKAA----LKSLALS 157 + R + + S + + S Y A+KAA + + Sbjct: 116 ENPEVRFVHVSTDEVYGDILKGSFTENDRLMPSSPYSATKAASDMLVLGWTRT 168 >4WPG-A nrPDB Length = 289 Score = 35.5 bits (81), Expect = 0.022, Method: Composition-based stats. Identities = 24/132 (18%), Positives = 45/132 (34%), Gaps = 26/132 (19%) Query: 8 VWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRLL 67 + +TG+ +G E G D A MD+ + +V V ++ Sbjct: 7 ILITGSNGQLGTELRYLLDERGVDYVAVDVAE-----------MDITNEDKVEAVFAQVK 55 Query: 68 AETERLDALV-NAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAI 126 LV + A + A + K + A+NV G+ N+ + G + Sbjct: 56 PT------LVYHCAAYTAVDAAEDEGKALNE---AINVTGSENIAKACGKY-----GATL 101 Query: 127 VTVASDAAHTPR 138 V +++D Sbjct: 102 VYISTDYVFDGN 113 >5K1S-A nrPDB Length = 362 Score = 35.2 bits (80), Expect = 0.026, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 30/76 (39%), Gaps = 3/76 (3%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGF--DQAFTQEQYPFATEVMDVADAAQVAQ 61 +G+ V +TGA G+G ++ GA+V +A Q + + V+ A Sbjct: 183 AGETVLITGASGGVGLSSVQLARLDGARVIAVTSSEAKVQALKEAGADEVIVSRGLDFAS 242 Query: 62 VCQRLLAETERLDALV 77 ++ +D V Sbjct: 243 DVRKRTQGAG-VDVAV 257 >5F5N-A nrPDB Length = 289 Score = 35.2 bits (80), Expect = 0.026, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 23/72 (31%), Gaps = 6/72 (8%) Query: 5 GKNVWVTGAGKGIGYATALAFVEAGAKVT------GFDQAFTQEQYPFATEVMDVADAAQ 58 + + VTGA G AT A + G V G D A + D+ D A Sbjct: 1 NRTILVTGATGTQGGATVRALLARGRPVRALVRDPGTDAARALAAAGVSLVTGDLNDQAS 60 Query: 59 VAQVCQRLLAET 70 + + Sbjct: 61 LRAAMADVHGVF 72 >1OC2-A nrPDB Length = 348 Score = 35.2 bits (80), Expect = 0.028, Method: Composition-based stats. Identities = 36/199 (18%), Positives = 53/199 (26%), Gaps = 48/199 (24%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGA---KVTGFDQ---------AFTQEQYPFATEVMDV 53 KN+ VTG IG +V VT D+ V D+ Sbjct: 5 KNIIVTGGAGFIGSNFVH-YVYNNHPDVHVTVLDKLTYAGNKANLEAILGDRVELVVGDI 63 Query: 54 ADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 ADA V ++ + DA+V+ A + S D N G + L + Sbjct: 64 ADAELVDKLAAKA-------DAIVHYAAESH----NDNSLNDPSPFIHTNFIGTYTLLEA 112 Query: 114 TMNQFRRQRGGAIVTVASDAAHTP----RIGM-----------------SAYGASKAALK 152 R V+ P G S Y ++KAA Sbjct: 113 ARKYDIRFHH---VSTDEVYGDLPLREDLPGHGEGPGEKFTAETNYNPSSPYSSTKAASD 169 Query: 153 SLALSVGLELAGSGVRCNV 171 + + N Sbjct: 170 LIVKAWVRSFGVKATISNC 188 >3OND-A nrPDB Length = 488 Score = 34.8 bits (79), Expect = 0.032, Method: Composition-based stats. Identities = 21/94 (22%), Positives = 32/94 (34%), Gaps = 10/94 (10%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVC 63 +GK V G G +G A A +AGA+V + E + V V Sbjct: 264 AGKVAVVAGYGD-VGKGCAAALKQAGARVIVT-EIDPICALQATMEGLQVLTLEDVVSEA 321 Query: 64 QRLLAETERLDALV--------NAAGILRMGATD 89 + T D ++ N A + +G D Sbjct: 322 DIFVTTTGNKDIIMLDHMKKMKNNAIVCNIGHFD 355 >3DMF-A nrPDB Length = 381 Score = 34.8 bits (79), Expect = 0.034, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 24/75 (32%), Gaps = 3/75 (4%) Query: 5 GKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQ 64 G+ V GAG G A L GA+V G + + A + Sbjct: 234 GRQVLDLGAGYG---ALTLPLARMGAEVVGVEDDLASVLSLQKGLEANALKAQALHSDVD 290 Query: 65 RLLAETERLDALVNA 79 L E R D +V Sbjct: 291 EALTEEARFDIIVTN 305 >2C20-A nrPDB Length = 330 Score = 34.8 bits (79), Expect = 0.039, Method: Composition-based stats. Identities = 30/167 (17%), Positives = 53/167 (31%), Gaps = 38/167 (22%) Query: 8 VWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV----MDVADAAQVAQVC 63 + + G IG V+ G V D T + D+ D A + V Sbjct: 4 ILICGGAGYIGSHAVKKLVDEGLSVVVVDNLQTGHEDAITEGAKFYNGDLRDKAFLRDVF 63 Query: 64 Q----RLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFR 119 + D+LV G+ Q + NV GA + M++F+ Sbjct: 64 TQENIEAVMHFAA-DSLV---GVSMEKPL---------QYYNNNVYGA-LCLLEVMDEFK 109 Query: 120 RQRGGAIVTVASDAAHTPRIGM------------SAYGASKAALKSL 154 + +S AA + + + YG +K A++ + Sbjct: 110 VDKF----IFSSTAATYGEVDVDLITEETMTNPTNTYGETKLAIEKM 152 >5LV5-A nrPDB Length = 403 Score = 34.0 bits (77), Expect = 0.054, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 32/76 (42%), Gaps = 4/76 (5%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGA-KVTGFDQAFTQEQYPFATEVMDVADAAQVAQ 61 GK V GAG GI ++ +AGA +V + + +Q + + D V Sbjct: 109 LRGKTVLDVGAGTGI---LSIFCAQAGARRVYAVEASAIWQQAREVVRLNGLEDRVHVLP 165 Query: 62 VCQRLLAETERLDALV 77 + ER+DA+V Sbjct: 166 GPVETVELPERVDAIV 181 >4J6F-A nrPDB Length = 382 Score = 34.0 bits (77), Expect = 0.054, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 21/64 (32%), Gaps = 1/64 (1%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAK-VTGFDQAFTQEQYPFATEVMDVADAAQVAQV 62 +G+ V VTGA G+G A GA + + + +A+ Sbjct: 206 AGETVLVTGASGGVGSAIIQLARARGAVPIAVAGPGKEAAMLDIGAQAVVTRGQGDLAEA 265 Query: 63 CQRL 66 + Sbjct: 266 VEAA 269 >2GGS-A nrPDB Length = 273 Score = 34.0 bits (77), Expect = 0.058, Method: Composition-based stats. Identities = 15/105 (14%), Positives = 41/105 (39%), Gaps = 14/105 (13%) Query: 9 WVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRLLA 68 +TGA +G + E + ++ + Q Y +D+ D ++ + Sbjct: 4 LITGASGQLGIELSRLLSERHEVIKVYNSSEIQGGYK-----LDLTDFPRLEDFIIK--- 55 Query: 69 ETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 +R D ++NAA + + + ++ ++ +N ++ + Sbjct: 56 --KRPDVIINAAAMTDVDKCEIEKEKAYK----INAEAVRHIVRA 94 >3DFZ-A nrPDB Length = 223 Score = 34.0 bits (77), Expect = 0.061, Method: Composition-based stats. Identities = 21/104 (20%), Positives = 36/104 (34%), Gaps = 17/104 (16%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTG--------FDQAFTQEQYPFATEVMD 52 +D G++V V G G I F++ GA +T ++ + Q + + Sbjct: 27 LDLKGRSVLVVGGGT-IATRRIKGFLQEGAAITVVAPTVSAEINEWEAKGQLRVKRKKVG 85 Query: 53 VADAAQV--------AQVCQRLLAETERLDALVNAAGILRMGAT 88 D V Q + + + + D LVN A G Sbjct: 86 EEDLLNVFFIVVATNDQAVNKFVKQHIKNDQLVNMASSFSDGNI 129 >3R0Q-C nrPDB Length = 376 Score = 33.6 bits (76), Expect = 0.074, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 33/78 (42%), Gaps = 8/78 (10%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQV 62 F GK V G G GI A+ +AGA+ +A + A + + + +V Sbjct: 62 FEGKTVLDVGTGSGI---LAIWSAQAGARKVYAVEATKMADHARALVKAN--NLDHIVEV 116 Query: 63 CQRLLAET---ERLDALV 77 + + + E++D ++ Sbjct: 117 IEGSVEDISLPEKVDVII 134 >1R66-A nrPDB Length = 337 Score = 33.6 bits (76), Expect = 0.076, Method: Composition-based stats. Identities = 36/172 (20%), Positives = 54/172 (31%), Gaps = 34/172 (19%) Query: 9 WVTGAGKGIGYATALAFVEAGA-------KVTGFDQAFTQEQYPFATEVMD----VADAA 57 VTG IG + AGA +V D + T +D + Sbjct: 4 LVTGGAGFIGSHFVRQLL-AGAYPDVPADEVIVLD-SLTYAGNRANLAPVDADPRLRFVH 61 Query: 58 QVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTF-AVNVGGAFNLFQQTMN 116 + L E +DA+V+ A + + F NV G L Q ++ Sbjct: 62 GDIRDAGLLARELRGVDAIVHFAAESHVDRSIAG-----ASVFTETNVQGTQTLLQCAVD 116 Query: 117 QFRRQRGGAIVTVA-----------SDAAHTPRIGMSAYGASKAALKSLALS 157 G +V V+ S +P S Y ASKA +A + Sbjct: 117 A----GVGRVVHVSTDEVYGSIDSGSWTESSPLEPNSPYAASKAGSDLVARA 164 >3N58-A nrPDB Length = 464 Score = 33.6 bits (76), Expect = 0.084, Method: Composition-based stats. Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 6/76 (7%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGA--KVTGFDQAFTQEQYPFATEVMDVADAAQVA 60 +GK V G G +G +A + AGA KVT D + EV+ + DAA A Sbjct: 245 MAGKVAVVCGYGD-VGKGSAQSLAGAGARVKVTEVDPICALQAAMDGFEVVTLDDAASTA 303 Query: 61 QVCQRLLAETERLDAL 76 + + T D + Sbjct: 304 DIV---VTTTGNKDVI 316 >4BKP-A nrPDB Length = 336 Score = 33.6 bits (76), Expect = 0.085, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 26/64 (40%), Gaps = 7/64 (10%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRL 66 + VTG +G A V GA + G D F +++ D+ D AQ + +++ Sbjct: 24 RILVTGGSGLVGKAI-QKVVADGAGLPGEDWVF------VSSKDADLTDTAQTRALFEKV 76 Query: 67 LAET 70 Sbjct: 77 QPTH 80 >6GCS-E nrPDB Length = 375 Score = 32.9 bits (74), Expect = 0.14, Method: Composition-based stats. Identities = 20/154 (12%), Positives = 52/154 (33%), Gaps = 15/154 (9%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVA-QV 62 +G V GA +G + G V + +++ T + V + ++ + Sbjct: 52 TGYTATVFGANGFLGSYLTAKLAKHGTTVVVPYREEMAKRHLKVTGDLGVVNFLEMDLRN 111 Query: 63 CQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQR 122 + + D +VN G + +++ + V+V GA ++ ++ Sbjct: 112 LESIDEAVRHSDIVVNLIG-------REYETKNFN-YYDVHVEGA----RRIAEAVKKHN 159 Query: 123 GGAIVTVASDAAHTPRIGMSAYGASKAALKSLAL 156 + V++ A + +K + + Sbjct: 160 IARYIHVSAFNAEIDSPSEFNH--TKGLGEQVTK 191 >4EUF-A nrPDB Length = 418 Score = 32.9 bits (74), Expect = 0.14, Method: Composition-based stats. Identities = 17/96 (17%), Positives = 29/96 (30%), Gaps = 24/96 (25%) Query: 6 KNVWVTGAGKGIGYA--TALAFVEAGAKVTG----------------------FDQAFTQ 41 K V + GA G G A ++AF A G F + + Sbjct: 61 KKVLIVGASSGFGLATRISVAFGGPEAHTIGVSYETGATDRRIGTAGWYNNIFFKEFAKK 120 Query: 42 EQYPFATEVMDVADAAQVAQVCQRLLAETERLDALV 77 + + D +V + + E ++D V Sbjct: 121 KGLVAKNFIEDAFSNETKDKVIKYIKDEFGKIDLFV 156 >2DFV-A nrPDB Length = 347 Score = 32.9 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 15/76 (19%) Query: 4 SGKNVWVTGAG--KGIGYATALA-------------FVEAGAKVTGFDQAFTQEQYPFAT 48 SGK+V +TGAG +G A A A F AK G D + Sbjct: 166 SGKSVLITGAGPLGLLGIAVAKASGAYPVIVSEPSDFRRELAKKVGADYVINPFEEDVVK 225 Query: 49 EVMDVADAAQVAQVCQ 64 EVMD+ D V + Sbjct: 226 EVMDITDGNGVDVFLE 241 >4R1U-A nrPDB Length = 349 Score = 32.5 bits (73), Expect = 0.16, Method: Composition-based stats. Identities = 21/137 (15%), Positives = 45/137 (32%), Gaps = 11/137 (8%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRL 66 V VTGAG I +E G V G + + E+ + + +V Sbjct: 29 TVCVTGAGGFIASWLVKLLLERGYTVRGTVRNPEDPKNGHLKELEGARERLTLHKV---D 85 Query: 67 LAETERLDALVN-AAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGA 125 L + + + ++V+ G+ + + ++ + A N + + + Sbjct: 86 LLDLQSIQSVVHGCHGVFHTASPVTDNPDEM-------LEPAVNGTKNVIIASAEAKVRR 138 Query: 126 IVTVASDAAHTPRIGMS 142 +V +S S Sbjct: 139 VVFTSSIGTVYMDPNTS 155 >4K28-A nrPDB Length = 269 Score = 32.5 bits (73), Expect = 0.16, Method: Composition-based stats. Identities = 16/42 (38%), Positives = 21/42 (50%), Gaps = 2/42 (4%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAG-AKVTGFDQAFTQEQY 44 +GK V G G G+G A A A EAG A +T D + + Sbjct: 124 AGKRALVIGCG-GVGSAIAYALAEAGIASITLCDPSTARMGA 164 >7REQ-A nrPDB Length = 727 Score = 32.5 bits (73), Expect = 0.17, Method: Composition-based stats. Identities = 17/93 (18%), Positives = 34/93 (36%), Gaps = 10/93 (10%) Query: 12 GAGKGIGYATALAFVEAGAKVTG-----FDQAFTQEQYPFATEVMDVADAA----QVAQV 62 G +G A A+ + G V + ++ V+ V+ A + Sbjct: 608 GHDRGQ-KVIATAYADLGFDVDVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPA 666 Query: 63 CQRLLAETERLDALVNAAGILRMGATDQLSKED 95 ++ L + R D L+ G++ D+L K+ Sbjct: 667 LRKELDKLGRPDILITVGGVIPEQDFDELRKDG 699 >6ACF-A nrPDB Length = 367 Score = 32.5 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 23/96 (23%), Positives = 30/96 (31%), Gaps = 18/96 (18%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD---QAFTQEQYPFATEVMDVADAAQ 58 GK V V G G + Y E GAK+ D +A + F + +D D Sbjct: 170 SLEGKVVAVQGVGN-VAYHLCRHLHEEGAKLIVTDINKEAVARAVEEFGAKAVDPNDIYG 228 Query: 59 VAQVCQRLLAETERLDALVNAA--GILRMGATDQLS 92 V D A GI+ QL Sbjct: 229 VE------------CDIFAPCALGGIINDQTIPQLK 252 >2C54-A nrPDB Length = 379 Score = 32.5 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 38/109 (34%), Gaps = 14/109 (12%) Query: 10 VTGAGKGIGYATALAFVEAGAKVTGFD----QAFTQEQYPFATEVMDVADAAQVAQVCQR 65 +TGAG I A G V D + T++ + ++D+ V + Sbjct: 34 ITGAGGFIASHIARRLKHEGHYVIASDWKKNEHMTEDMFCDEFHLVDLR-------VMEN 86 Query: 66 LLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT 114 L TE +D + N A + Q + N +FN+ + Sbjct: 87 CLKVTEGVDHVFNLAADMGGMGFIQSNH---SVIMYNNTMISFNMIEAA 132 >5YWN-A nrPDB Length = 334 Score = 32.1 bits (72), Expect = 0.24, Method: Composition-based stats. Identities = 19/133 (14%), Positives = 41/133 (30%), Gaps = 15/133 (11%) Query: 8 VWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMD----VADAAQVAQVC 63 V+V+GA + + G KV G ++ + D V + Sbjct: 5 VFVSGATGYLAQQIIALVLSKGYKVVGSVRSEEKGANLKKLYGDDFSYEVVKVLEQKGAF 64 Query: 64 QRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFR--RQ 121 L + + ++ A + ED ++ + A N + + + Sbjct: 65 DEALKKHPEVTIFLHTA------SPVTFEVEDTEKEI---LIPAINGTKYVLQSIKDVAP 115 Query: 122 RGGAIVTVASDAA 134 + +V +S A Sbjct: 116 QITRVVYTSSVVA 128 >2YQ5-A nrPDB Length = 343 Score = 31.7 bits (71), Expect = 0.28, Method: Composition-based stats. Identities = 15/33 (45%), Positives = 17/33 (51%) Query: 17 IGYATALAFVEAGAKVTGFDQAFTQEQYPFATE 49 IG A A F GAKV +D A+ E PF T Sbjct: 159 IGSAVAEIFSAMGAKVIAYDVAYNPEFEPFLTY 191 >6BI4-A nrPDB Length = 346 Score = 31.7 bits (71), Expect = 0.31, Method: Composition-based stats. Identities = 30/160 (18%), Positives = 51/160 (31%), Gaps = 21/160 (13%) Query: 7 NVWVTGAGKGIGYATALAFVE--AGAKVTGFDQAFTQEQYPFATEVMD------VADAAQ 58 N+ VTG IG ++ K+ FD + D V Q Sbjct: 26 NILVTGGAGFIGSNFVHYMLQSYETYKIINFDALTYSGNLNNVKSIQDHPNYYFVKGEIQ 85 Query: 59 VAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQT--MN 116 ++ + ++ E + +VN A S E+ + NV G L + Sbjct: 86 NGELLEHVIKE-RDVQVIVNFAAESH----VDRSIENPIPFYDTNVIGTVTLLELVKKYP 140 Query: 117 QFR------RQRGGAIVTVASDAAHTPRIGMSAYGASKAA 150 + + G++ TP S Y +SKA+ Sbjct: 141 HIKLVQVSTDEVYGSLGKTGRFTEETPLAPNSPYSSSKAS 180 >6GBN-A nrPDB Length = 438 Score = 31.3 bits (70), Expect = 0.35, Method: Composition-based stats. Identities = 20/91 (21%), Positives = 32/91 (35%), Gaps = 13/91 (14%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTG--FDQAFTQEQYPFATEVMDVADAAQVA 60 +GK V G G +G +A + AGA+V D + EV +ADA + A Sbjct: 217 MAGKVAVVAGYGD-VGKGSAASLRGAGARVIVTEIDPICALQAAMDGYEVKKMADAVKRA 275 Query: 61 QVCQRLL--------AETERLD--ALVNAAG 81 + + + +V G Sbjct: 276 DIVVTATGNKNIITGEHFKAMRDKVIVCNIG 306 >5EGS-A nrPDB Length = 376 Score = 31.3 bits (70), Expect = 0.37, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 31/76 (40%), Gaps = 4/76 (5%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGA-KVTGFDQAFTQEQYPFATEVMDVADAAQVAQ 61 GK V GAG GI ++ +AGA +V + + +Q + D V Sbjct: 82 LRGKTVLDVGAGTGI---LSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLP 138 Query: 62 VCQRLLAETERLDALV 77 + E++DA+V Sbjct: 139 GPVETVELPEQVDAIV 154 >1EQ2-A nrPDB Length = 310 Score = 31.3 bits (70), Expect = 0.39, Method: Composition-based stats. Identities = 38/244 (15%), Positives = 68/244 (27%), Gaps = 31/244 (12%) Query: 8 VWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRLL 67 + VTG IG A + G +++AD +++ Sbjct: 2 IIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVDLNIADYMDKEDFLIQIM 61 Query: 68 --AETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGG----AFNLFQQTMNQFRRQ 121 E ++ I GA ++ D + N ++ + Sbjct: 62 AGEEFGDVE------AIFHEGACSSTTEWDGKYMMDNNYQYSKELLHYCLEREIPFLYAS 115 Query: 122 R----GGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGS--GVR-CNVVSP 174 GG T + ++ YG SK + E G R NV P Sbjct: 116 SAATYGGR--TSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANSQIVGFRYFNVYGP 173 Query: 175 -----GSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 GS + ++ E ++ E FK ++A+ L+ + Sbjct: 174 REGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRD-----FVYVGDVADVNLWFLENG 228 Query: 230 ASHI 233 S I Sbjct: 229 VSGI 232 >2GAS-A nrPDB Length = 307 Score = 31.3 bits (70), Expect = 0.41, Method: Composition-based stats. Identities = 15/82 (18%), Positives = 30/82 (36%), Gaps = 7/82 (8%) Query: 7 NVWVTGAGKGIGYATALAFVEAG-------AKVTGFDQAFTQEQYPFATEVMDVADAAQV 59 + + G IG A ++AG K T+E+ + + V Sbjct: 4 KILILGPTGAIGRHIVWASIKAGNPTYALVRKTITAANPETKEELIDNYQSLGVILLEGD 63 Query: 60 AQVCQRLLAETERLDALVNAAG 81 + L+ +++D ++ AAG Sbjct: 64 INDHETLVKAIKQVDIVICAAG 85 >4EJ6-A nrPDB Length = 370 Score = 30.9 bits (69), Expect = 0.46, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 28/84 (33%), Gaps = 5/84 (5%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQ----EQYPFATEVMDVADAAQV 59 +G V + G G IG T AGA + AT +D + V Sbjct: 182 AGSTVAILGGGV-IGLLTVQLARLAGATTVILSTRQATKRRLAEEVGATATVDPSAGDVV 240 Query: 60 AQVCQRLLAETERLDALVNAAGIL 83 + + +D ++ AG+ Sbjct: 241 EAIAGPVGLVPGGVDVVIECAGVA 264 >5ENV-A nrPDB Length = 347 Score = 30.9 bits (69), Expect = 0.49, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 33/86 (38%), Gaps = 7/86 (8%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEA-GAKVTGFDQAFTQEQY---PFATEVMDVADAAQ 58 +G V ++GA G+G + A+ + +A G +V G D +E+ +D Sbjct: 168 MAGHWVAISGAAGGLG-SLAVQYAKAMGYRVLGIDGGEGKEELFRSIGGEVFIDFTKEKD 226 Query: 59 VAQVC--QRLLAETERLDALVNAAGI 82 + ++ V+ A I Sbjct: 227 IVGAVLKATDGGAHGVINVSVSEAAI 252 >1RPN-A nrPDB Length = 335 Score = 30.9 bits (69), Expect = 0.50, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 24/68 (35%), Gaps = 10/68 (14%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQE----------QYPFATEVMDVAD 55 ++ VTG G A +E G +V G + + + E D+AD Sbjct: 15 RSALVTGITGQDGAYLAKLLLEKGYRVHGLVARRSSDTRWRLRELGIEGDIQYEDGDMAD 74 Query: 56 AAQVAQVC 63 A V + Sbjct: 75 ACSVQRAV 82 >5N2I-A nrPDB Length = 232 Score = 30.9 bits (69), Expect = 0.53, Method: Composition-based stats. Identities = 13/47 (27%), Positives = 19/47 (40%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFAT 48 D SG ++ V G G A F AG +V ++ + Q A Sbjct: 16 DVSGLSIAVLGGTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAE 62 >5A3V-A nrPDB Length = 329 Score = 30.9 bits (69), Expect = 0.55, Method: Composition-based stats. Identities = 28/109 (25%), Positives = 42/109 (38%), Gaps = 15/109 (13%) Query: 1 MDFSGKNV--WVTGAGKGIGYATALAFVE-AGAKVTGFDQAFTQEQYP--FATEVMDVAD 55 +D +GK VT A G+G A+ + A A VT A E A EV+D Sbjct: 150 LDGTGKKANILVTAASGGVG-HYAVQLAKLANAHVTATCGARNIEFVKSLGADEVLDYKT 208 Query: 56 AAQVAQVCQRLLAETE-RLDALVNAA-GILRMGATDQLSKEDWQQTFAV 102 L + + + DA+V+ A GI LS+ + + Sbjct: 209 PEG-----AALKSPSGKKYDAVVHCANGIPFSVFEPNLSENG--KVIDI 250 >5I1W-A nrPDB Length = 500 Score = 30.9 bits (69), Expect = 0.56, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 32/84 (38%), Gaps = 14/84 (16%) Query: 149 AALKSLAL------SVGLELAGSGVRCNVVSPGSTDTDMQRTL-------WVSDDAEEQR 195 AA + L+ S +E G R N V P +T +L W D +E+ Sbjct: 358 AAYRHLSRADYHCPSAAMEYIAYGGRVNTVDPAATAVPRGASLKTFYMVAWTDPDEDEEH 417 Query: 196 IRGFGEQFKLGI-PLGKIARPQEI 218 +R E ++ G + P E+ Sbjct: 418 LRWIREIYRDIHSATGGVPTPDEV 441 >3X2F-A nrPDB Length = 411 Score = 30.9 bits (69), Expect = 0.58, Method: Composition-based stats. Identities = 27/145 (18%), Positives = 50/145 (34%), Gaps = 26/145 (17%) Query: 4 SGKNVWVTGAGKG-IGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQV 62 +GKNV V AG G G AL GA+V + + + V + ++ Sbjct: 196 AGKNVVV--AGYGWCGRGIALRAAGLGARVIVT-EVDPVKAVEAIMDGFTVMPMKEAVKI 252 Query: 63 CQRLLAETERLDAL-------------VNAAGIL----RMGATDQLSKEDWQQTFAVNVG 105 ++ + D L + AG + ++++ E ++ NV Sbjct: 253 ADFVITASGNTDVLSKEDILSLKDGAVLANAGHFNVEIPVRVLEEIAVEKFEA--RPNVT 310 Query: 106 GAFNLFQQTMNQFRRQRGGAIVTVA 130 G +T+ G +V +A Sbjct: 311 GYTLENGKTVFLLAE---GRLVNLA 332 >3NJ4-A nrPDB Length = 435 Score = 30.9 bits (69), Expect = 0.59, Method: Composition-based stats. Identities = 28/139 (20%), Positives = 47/139 (33%), Gaps = 22/139 (15%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD----QAFTQEQYPFATEVMDVADAA-- 57 +GK V G G +G A A GA+V + A + MD A Sbjct: 215 AGKVAVVAGYGD-VGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGN 273 Query: 58 ---QVAQVCQRLLA-ETERL--DALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 111 +L E++ DA+V G + + E VN Sbjct: 274 IFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNE--NAVEKVN-------I 324 Query: 112 QQTMNQFRRQRGGAIVTVA 130 + ++++R + G I+ +A Sbjct: 325 KPQVDRYRLKNGRRIILLA 343 >1O89-A nrPDB Length = 345 Score = 30.9 bits (69), Expect = 0.59, Method: Composition-based stats. Identities = 8/29 (27%), Positives = 12/29 (41%) Query: 8 VWVTGAGKGIGYATALAFVEAGAKVTGFD 36 + VTGA G+G + G +V Sbjct: 171 IVVTGASGGVGSTAVALLHKLGYQVVAVS 199 >5TC4-A nrPDB Length = 316 Score = 30.5 bits (68), Expect = 0.68, Method: Composition-based stats. Identities = 21/98 (21%), Positives = 35/98 (35%), Gaps = 16/98 (16%) Query: 5 GKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQ 64 GKNV V G K +G A+ GA + P + ++ + Sbjct: 159 GKNVVVAGRSKNVGMPIAMLLHTDGAH-----------ERPGGDATVTISHRYTPK---E 204 Query: 65 RLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAV 102 +L T D +++AAGI + D + + V Sbjct: 205 QLKKHTILADIVISAAGIPNLITADMIKEGA--AVIDV 240 >2X86-A nrPDB Length = 357 Score = 30.5 bits (68), Expect = 0.71, Method: Composition-based stats. Identities = 15/101 (14%), Positives = 29/101 (28%), Gaps = 8/101 (7%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQR 65 + + VTG IG A + G +++AD + Sbjct: 47 RMIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVDLNIADYMDKEDFLIQ 106 Query: 66 LL--AETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNV 104 ++ E ++ I GA ++ D + N Sbjct: 107 IMAGEEFGDVE------AIFHEGACSSTTEWDGKYMMDNNY 141 >4PVC-A nrPDB Length = 342 Score = 30.5 bits (68), Expect = 0.72, Method: Composition-based stats. Identities = 20/137 (14%), Positives = 47/137 (34%), Gaps = 19/137 (13%) Query: 8 VWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMD-------VADAAQVA 60 V+V+GA I ++ KV G ++ + + + V D +++ Sbjct: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62 Query: 61 QVCQRLLAETER-LDALVNAAGILRMGATDQLSKEDWQQTF-AVN-VGGAFNLFQQTMNQ 117 + + + + +++ A ++ + AVN V G + ++ Sbjct: 63 A-FDHVFQKHGKDIKIVLHTA----SPFCFDITDSERDLLIPAVNGVKGILHSIKKYAAD 117 Query: 118 FRRQRGGAIVTVASDAA 134 +V +S AA Sbjct: 118 SVE----RVVLTSSYAA 130 >2OWO-A nrPDB Length = 671 Score = 30.5 bits (68), Expect = 0.72, Method: Composition-based stats. Identities = 17/58 (29%), Positives = 24/58 (41%), Gaps = 1/58 (1%) Query: 3 FSGKNVWVTGAGKGIGYATAL-AFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQV 59 F+GK V +TG+ + A VE GAKV G T +A A ++ Sbjct: 598 FAGKTVVLTGSLSQMSRDDAKARLVELGAKVAGSVSKKTDLVIAGEAAGSKLAKAQEL 655 >5ZZ6-A nrPDB Length = 208 Score = 30.2 bits (67), Expect = 0.81, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 26/65 (40%), Gaps = 3/65 (4%) Query: 9 WVTGAGKGIGYATA--LAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRL 66 V GAG IG A A E G ++ G + + A + V+D +++ + + Sbjct: 86 VVVGAGN-IGRAVANYTVMKEKGFRIIGIFDSDPSKIGKEAAPGLTVSDVSELEKFVEEH 144 Query: 67 LAETE 71 E Sbjct: 145 GVEIG 149 >4A10-A nrPDB Length = 447 Score = 30.2 bits (67), Expect = 0.83, Method: Composition-based stats. Identities = 24/143 (16%), Positives = 47/143 (32%), Gaps = 30/143 (20%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVA--------- 54 G V + GA G+G + A+ FV+ G + + Q++ D+ Sbjct: 220 QGDIVLIWGASGGLG-SYAIQFVKNGGGIPVAVVSSAQKEAAVRALGCDLVINRAELGIT 278 Query: 55 -DAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQ 113 D A + + +L +V AG + + + Sbjct: 279 DDIADDPRRVVETGRKLAKL--VVEKAGREPDIVFEHTGRVTF----------------- 319 Query: 114 TMNQFRRQRGGAIVTVASDAAHT 136 ++ +RGG +VT S + + Sbjct: 320 GLSVIVARRGGTVVTCGSSSGYL 342 >3H9U-A nrPDB Length = 436 Score = 30.2 bits (67), Expect = 0.92, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 31/90 (34%), Gaps = 13/90 (14%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTG--FDQAFTQEQYPFATEVMDVADAAQVAQ 61 +GK V G G +G A A GA+V D + +V+ V D + A Sbjct: 210 AGKTACVCGYGD-VGKGCAAALRGFGARVVVTEVDPINALQAAMEGYQVLLVEDVVEEAH 268 Query: 62 VCQRLL--------AETERL--DALVNAAG 81 + R+ DA+V G Sbjct: 269 IFVTTTGNDDIITSEHFPRMRDDAIVCNIG 298 >1DB3-A nrPDB Length = 372 Score = 30.2 bits (67), Expect = 0.94, Method: Composition-based stats. Identities = 11/76 (14%), Positives = 25/76 (32%), Gaps = 15/76 (19%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV--------------- 50 K +TG G A +E G +V G + + + Sbjct: 2 KVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPHTCNPKFHLHY 61 Query: 51 MDVADAAQVAQVCQRL 66 D++D + + ++ + + Sbjct: 62 GDLSDTSNLTRILREV 77 >1LU9-A nrPDB Length = 287 Score = 29.8 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 11/68 (16%), Positives = 20/68 (29%), Gaps = 4/68 (5%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATE----VMDVADAA 57 GK V +G +A GA+V + + Q + ++V A Sbjct: 116 SVKGKKAVVLAGTGPVGMRSAALLAGEGAEVVLCGRKLDKAQAAADSVNKRFKVNVTAAE 175 Query: 58 QVAQVCQR 65 + Sbjct: 176 TADDASRA 183 >2VN8-A nrPDB Length = 375 Score = 29.8 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 26/78 (33%), Gaps = 3/78 (3%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVC 63 +GK V + GA G+G A VT + + DV D Sbjct: 183 TGKRVLILGASGGVGTFAIQVMKAWDAHVTAV-CSQDASELVRKLGADDVIDYKS--GSV 239 Query: 64 QRLLAETERLDALVNAAG 81 + L + D +++ G Sbjct: 240 EEQLKSLKPFDFILDNVG 257 >2Q4B-A nrPDB Length = 253 Score = 29.4 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 25/77 (32%), Gaps = 14/77 (18%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAK------VTGFDQAFTQEQYPFATEVMDVADAAQVA 60 V VTGA G ++ G+ + Q + + D+ DA + Sbjct: 6 TVLVTGASGRTGQ-IVYKKLKEGSDKFVAKGLVRSAQGKEKIGGEADVFIGDITDADSIN 64 Query: 61 QVCQRLLAETERLDALV 77 Q +DALV Sbjct: 65 PAFQ-------GIDALV 74 >1IE3-A nrPDB Length = 312 Score = 29.4 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 31/126 (24%), Positives = 48/126 (38%), Gaps = 12/126 (9%) Query: 7 NVWVTGAGKGIGYATALAFVEA---GAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVC 63 V V GA GIG A AL G++++ +D A A ++ + A ++ Sbjct: 2 KVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPV--TPGVAVDLSHIPTAVKIKGFS 59 Query: 64 -QRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQR 122 + E D ++ +AG+ R D+ F VN G NL QQ + Sbjct: 60 GEDATPALEGADVVLISAGVARKPGMDR------SDLFNVNAGIVKNLVQQVAKTCPKAC 113 Query: 123 GGAIVT 128 G I Sbjct: 114 IGIITN 119 >4N18-A nrPDB Length = 332 Score = 29.4 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 19/63 (30%), Gaps = 14/63 (22%) Query: 17 IGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRLLAET-ERLDA 75 IG A G +V+G+ ++ Q + L LD Sbjct: 167 IGGYIADQLARLGYRVSGWSRSEKQLAGVTCYRG-------------EEALDHFLGSLDG 213 Query: 76 LVN 78 L+N Sbjct: 214 LIN 216 >2HK7-A nrPDB Length = 269 Score = 29.4 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 29/65 (44%), Gaps = 2/65 (3%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVAD-AAQVAQVCQ 64 K++ V GAG G A A V+ GAKV +++ + ++V + +V Q Sbjct: 124 KSILVLGAG-GASRAVIYALVKEGAKVFLWNRTKEKAIKLAQKFPLEVVNSPEEVIDKVQ 182 Query: 65 RLLAE 69 ++ Sbjct: 183 VIVNT 187 >1YXY-A nrPDB Length = 234 Score = 29.4 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 18/57 (31%), Gaps = 7/57 (12%) Query: 116 NQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVV 172 + +GG IV + G Y + + L E G+R N V Sbjct: 9 KLMEQLKGGIIV------SCQALPGEPLYSET-GGIMPLMAKAAQEAGAVGIRANSV 58 >2ZJ1-A nrPDB Length = 495 Score = 29.4 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 25/72 (34%), Gaps = 2/72 (2%) Query: 5 GKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQ 64 GK V + G G +G A A GA+V+ + E DV + Sbjct: 275 GKKVLICGYGD-VGKGCAEAMKGQGARVSVT-EIDPINALQAMMEGFDVVTVEEAIGDAD 332 Query: 65 RLLAETERLDAL 76 ++ T D + Sbjct: 333 IVVTATGNKDII 344 >3K8Z-A nrPDB Length = 423 Score = 29.4 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 26/91 (28%), Positives = 36/91 (39%), Gaps = 15/91 (16%) Query: 1 MDFSGKNVWVTGAGKGIGYA---TALAFVEAGAKVTGFDQAFTQEQYPFA---TEVMDVA 54 +D G V V +G G A A +AGAKV G A+ P ++D Sbjct: 216 IDIKGARVVV----QGFGNAGSYLAKFMHDAGAKVVGISDAYGGLYDPEGLDIDYLLDRR 271 Query: 55 DA-AQVAQVCQRLLAETERL----DALVNAA 80 D+ V ++ + E L D LV AA Sbjct: 272 DSFGTVTKLFNDTITNQELLELDCDILVPAA 302 >5ZZM-A nrPDB Length = 426 Score = 29.0 bits (64), Expect = 1.7, Method: Composition-based stats. Identities = 21/79 (26%), Positives = 26/79 (32%), Gaps = 14/79 (17%) Query: 9 WVTGAGK--------GIGYA--TALAFVEAGAKVTGFDQAF--TQEQYPFATEVMDVADA 56 +TG+ K G G A A A GA V FD A QE+ V D Sbjct: 44 VITGSRKAPHPKYFVGEGKAVEIAEAVKATGASVVLFDHALSPAQERNLERLCECRVIDR 103 Query: 57 AQ--VAQVCQRLLAETERL 73 + QR +L Sbjct: 104 TGLILDIFAQRARTHEGKL 122 >3JTM-A nrPDB Length = 351 Score = 29.0 bits (64), Expect = 1.7, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 24/78 (30%), Gaps = 11/78 (14%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQ 61 D GK + GAG+ IG G + D+ + + A+ Sbjct: 161 DLEGKTIGTVGAGR-IGKLLLQRLKPFGCNLLYHDRLQMAPEL----------EKETGAK 209 Query: 62 VCQRLLAETERLDALVNA 79 + L + D +V Sbjct: 210 FVEDLNEMLPKCDVIVIN 227 >2A9F-A nrPDB Length = 398 Score = 29.0 bits (64), Expect = 1.7, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 27/80 (33%), Gaps = 5/80 (6%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGA-KVTGFDQ---AFTQEQYPFATEVMDVADAA 57 ++ V G G G + + AGA KVT D+ QE A +D+A Sbjct: 185 SLDEVSIVVNGGGSA-GLSITRKLLAAGATKVTVVDKFGIINEQEAAQLAPHHLDIAKVT 243 Query: 58 QVAQVCQRLLAETERLDALV 77 L E D + Sbjct: 244 NREFKSGTLEDALEGADIFI 263 >1XDW-A nrPDB Length = 331 Score = 29.0 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 21/85 (24%), Positives = 32/85 (37%), Gaps = 15/85 (17%) Query: 10 VTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVM--DVADAAQVAQVCQRLL 67 V G G+ IG A F GA V G D + + T+V +V + + + + + Sbjct: 151 VVGLGR-IGRVAAQIFHGMGATVIGEDVFEIKGIEDYCTQVSLDEVLEKSDIITIHAPYI 209 Query: 68 AETERL---D---------ALVNAA 80 E + D LVN A Sbjct: 210 KENGAVVTRDFLKKMKDGAILVNCA 234 >3VPX-A nrPDB Length = 364 Score = 28.6 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 14/47 (29%), Positives = 17/47 (36%), Gaps = 1/47 (2%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFAT 48 +GK V V G G + YA E GAK+ D Q Sbjct: 170 SLAGKTVAVQGVGN-VAYALCEYLHEEGAKLIITDINEEAVQRAVDA 215 >6ACQ-A nrPDB Length = 302 Score = 28.6 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 28/71 (39%), Gaps = 6/71 (8%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQR 65 K V V GAG +G A AF G +V D + F +D + V + Sbjct: 22 KKVCVIGAGT-MGSGIAQAFAAKGFEVVLRDI-----KDEFVDRGLDFINKNLSKLVKKG 75 Query: 66 LLAETERLDAL 76 + E +++ L Sbjct: 76 KIEEATKVEIL 86 >4UUM-A nrPDB Length = 341 Score = 28.6 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 17/133 (12%), Positives = 41/133 (30%), Gaps = 24/133 (18%) Query: 36 DQAFTQEQYPFATEVMDVAD--------AAQVAQVCQRLLAETER----LDALVNAAGIL 83 ++A+ + +V DV D + VA + Q + + +D L + + Sbjct: 160 NRAYYEVASKLGVDVKDVHDIIVWGNHGESMVADLTQATFTKEGKTQKVVDVLDHD--YV 217 Query: 84 RMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRR----QRGGAIVTVASDAAHTPRI 139 ++ W A + + + + G ++++ P Sbjct: 218 FDTFFKKIGHRAWDILEHRGFTSAASPTKAAIQHMKAWLFGTAPGEVLSMG-----IPVP 272 Query: 140 GMSAYGASKAALK 152 + YG K + Sbjct: 273 EGNPYGI-KPGVV 284 >2ZSK-A nrPDB Length = 226 Score = 28.6 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 9/48 (18%), Positives = 18/48 (37%) Query: 22 ALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRLLAE 69 A A AGA++ F + ++V + + V + +L Sbjct: 66 AKALERAGAELIAFAANTPHLVFDDVQREVNVPMVSIIDAVAEEILKR 113 >1NHQ-A nrPDB Length = 447 Score = 28.6 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 19/47 (40%), Positives = 21/47 (44%), Gaps = 1/47 (2%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDV 53 NV V G+G IG A AF +AG KVT D E DV Sbjct: 151 NVVVIGSGY-IGIEAAEAFAKAGKKVTVIDILDRPLGVYLDKEFTDV 196 >3R9I-A nrPDB Length = 260 Score = 28.6 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 21/107 (19%), Positives = 34/107 (31%), Gaps = 13/107 (12%) Query: 6 KNVWVTGAGKGIGY-----ATALAFVEAGAKVTGFDQAFTQEQYPFA-----TEVMDVAD 55 + + VT G+G A A + G K D A V D + Sbjct: 3 RIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVIDFAIGLRNLDLIMGCERRVVYDFVN 62 Query: 56 AAQVAQVCQRLLAETERLDAL-VNAAGILRMGATDQLSKEDWQQTFA 101 Q + L + +R + L + A R D L++E + Sbjct: 63 VIQGDATLNQALIKDKRTENLYILPASQTRDK--DALTREGVAKVLD 107 >5ER0-A nrPDB Length = 518 Score = 28.6 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 19/64 (29%), Positives = 23/64 (35%), Gaps = 1/64 (1%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQR 65 K + V GAG IG A A+ G VT D F + DV + Q Sbjct: 198 KRITVIGAGY-IGAELAEAYSTTGHDVTLIDAMARVMPKYFDADFTDVIEQDYRDHGVQL 256 Query: 66 LLAE 69 L E Sbjct: 257 ALGE 260 >4WOK-A nrPDB Length = 336 Score = 28.6 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 14/62 (22%), Positives = 19/62 (30%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRL 66 NV V G IG TA G +D T Q D A++ + + Sbjct: 13 NVLVVGGAGFIGSHTAKLLAGQGYAPVVYDNLSTGHQSAVRWGDFVEGDILDQARLVETM 72 Query: 67 LA 68 Sbjct: 73 EK 74 >1ZDL-A nrPDB Length = 517 Score = 28.6 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 12/28 (42%), Gaps = 1/28 (3%) Query: 9 WVTGAGKGIGYATALAFVEAGAKVTGFD 36 V G G G G A A + G KV D Sbjct: 36 LVIGGGSG-GLACAKEAAQLGKKVAVAD 62 >1MLD-A nrPDB Length = 314 Score = 28.2 bits (62), Expect = 3.0, Method: Composition-based stats. Identities = 24/116 (20%), Positives = 39/116 (33%), Gaps = 14/116 (12%) Query: 6 KNVWVTGAGKGIGYATALAFVEA--GAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVC 63 K V GA GIG +L + +++T +D A T A ++ + A V Sbjct: 2 KVA-VLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHT---PGVAADLSHIETRATVKGYL 57 Query: 64 --QRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQ 117 ++L + D +V AG+ R + F N L Sbjct: 58 GPEQLPDCLKGCDVVVIPAGVPRKPGMTR------DDLFNTNATIVATLTAACAQH 107 >1C0L-A nrPDB Length = 363 Score = 28.2 bits (62), Expect = 3.1, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 17/37 (45%), Gaps = 1/37 (2%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQE 42 K V V G+G IG ++AL G V + ++ Sbjct: 7 KRVVVLGSGV-IGLSSALILARKGYSVHILARDLPED 42 >4K22-A nrPDB Length = 365 Score = 28.2 bits (62), Expect = 3.1, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 24/71 (33%), Gaps = 6/71 (8%) Query: 7 NVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRL 66 V G +G A A +G +V +Q + A + V+ + ++L Sbjct: 6 VAIVGGGM--VGLAVACGLQGSGLRVAVLEQRVQEPLAANAPPQLRVS---AINAASEKL 60 Query: 67 LAETERL-DAL 76 L D L Sbjct: 61 LTRLGVWQDIL 71 >4E0B-A nrPDB Length = 313 Score = 28.2 bits (62), Expect = 3.2, Method: Composition-based stats. Identities = 20/101 (19%), Positives = 35/101 (34%), Gaps = 7/101 (6%) Query: 4 SGKNVWVTGAGKGIGYATALAFVE---AGAKVTGFDQAFTQEQYPFATEVMDVADAAQVA 60 + K + GA GIG A AL AG+ + +D A A ++ + + Sbjct: 3 AMKVAVI-GAAGGIGQALALLLKNRLPAGSDLALYDIAPV--TPGVAADLSHIPTHVSIK 59 Query: 61 QVCQRLLA-ETERLDALVNAAGILRMGATDQLSKEDWQQTF 100 E D ++ +AG+ R D+ + Sbjct: 60 GYAGEDPTPALEGADVVLISAGVARKPGMDRADLFNVNAGI 100 >3ZXS-A nrPDB Length = 522 Score = 28.2 bits (62), Expect = 3.2, Method: Composition-based stats. Identities = 10/71 (14%), Positives = 19/71 (26%), Gaps = 4/71 (5%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQR 65 K + A + A E G +V E++ A + Sbjct: 61 KIALILAAMR----KFARRLQERGFRVAYSRLDDPDTGPSIGAELLRRAAETGAREAVAT 116 Query: 66 LLAETERLDAL 76 + ++AL Sbjct: 117 RPGDWRLIEAL 127 >4WLE-A nrPDB Length = 340 Score = 28.2 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 24/116 (20%), Positives = 39/116 (33%), Gaps = 14/116 (12%) Query: 6 KNVWVTGAGKGIGYATALAFVEA--GAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVC 63 K V GA GIG +L + +++T +D A T A ++ + A V Sbjct: 28 KVA-VLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHT---PGVAADLSHIETKAAVKGYL 83 Query: 64 --QRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQ 117 ++L + D +V AG+ R + F N L Sbjct: 84 GPEQLPDCLKGCDVVVIPAGVPRKPGMTR------DDLFNTNATIVATLTAACAQH 133 >6C55-A nrPDB Length = 340 Score = 28.2 bits (62), Expect = 3.6, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 13/32 (40%), Gaps = 1/32 (3%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTG 34 GK + V G G G+A A + G V Sbjct: 15 LQGKKIAVVGYGS-QGHAHAQNLKDNGYDVVI 45 >4UUP-A nrPDB Length = 341 Score = 28.2 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 9/20 (45%), Positives = 11/20 (55%) Query: 8 VWVTGAGKGIGYATALAFVE 27 V +TGA IGYA A + Sbjct: 7 VLITGAAGQIGYALAFRIAK 26 >1EDZ-A nrPDB Length = 320 Score = 27.8 bits (61), Expect = 3.9, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 22/69 (31%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQ 61 GK V + +G A GA V D Q+ + ++ + + Sbjct: 174 RLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGE 233 Query: 62 VCQRLLAET 70 + LL + Sbjct: 234 YSEDLLKKC 242 >3NE8-A nrPDB Length = 234 Score = 27.8 bits (61), Expect = 3.9, Method: Composition-based stats. Identities = 11/64 (17%), Positives = 22/64 (34%), Gaps = 4/64 (6%) Query: 20 ATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVA---QVCQRLLAETERLDA- 75 A A + E+ KV D +E ++D+ A +++ + Sbjct: 106 AIAKSLAESENKVDLLDGLPKEESLELTDILLDLTRRETHAFSINFANNVVSNLSKSHIN 165 Query: 76 LVNA 79 L+N Sbjct: 166 LINN 169 >4A26-A nrPDB Length = 300 Score = 27.8 bits (61), Expect = 4.1, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 19/53 (35%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDV 53 ++ +GK V G +G A ++ A VT + E D+ Sbjct: 161 IEMAGKRAVVLGRSNIVGAPVAALLMKENATVTIVHSGTSTEDMIDYLRTADI 213 >5NHS-A nrPDB Length = 296 Score = 27.8 bits (61), Expect = 4.2, Method: Composition-based stats. Identities = 10/49 (20%), Positives = 18/49 (36%) Query: 5 GKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDV 53 G+N + G +G AL + AG V+ + + D+ Sbjct: 168 GRNATIVGVSNHVGRPMALELLIAGCTVSCCHKFTPADVLQTHVRDADI 216 >3HG7-A nrPDB Length = 324 Score = 27.8 bits (61), Expect = 4.3, Method: Composition-based stats. Identities = 10/42 (23%), Positives = 16/42 (38%), Gaps = 1/42 (2%) Query: 3 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQY 44 G+ + + G G IG A G KV G ++ + Sbjct: 138 LKGRTLLILGTGS-IGQHIAHTGKHFGMKVLGVSRSGRERAG 178 >4PRK-A nrPDB Length = 336 Score = 27.8 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 13/34 (38%), Positives = 16/34 (47%) Query: 17 IGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV 50 IG A A F GAKV +D + E P+ T Sbjct: 157 IGSAVAQIFSAMGAKVLAYDVIYNPEVEPYLTYA 190 >5GXF-A nrPDB Length = 330 Score = 27.8 bits (61), Expect = 4.8, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 20/61 (32%) Query: 8 VWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRLL 67 V VTGA G+G G +V Y + + ++ + +R L Sbjct: 153 VLVTGAAGGVGSVATAILAHLGYEVAAVTGRPETADYLTSLGATQIVARDEINETVKRPL 212 Query: 68 A 68 Sbjct: 213 E 213 >1YB5-A nrPDB Length = 351 Score = 27.8 bits (61), Expect = 4.8, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 29/76 (38%), Gaps = 3/76 (3%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVC 63 +G++V V GA G+G A G K+ G ++ +V + +V Sbjct: 170 AGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFNHREV-NYI 228 Query: 64 QRLLAETE--RLDALV 77 ++ +D ++ Sbjct: 229 DKIKKYVGEKGIDIII 244 >4OH1-A nrPDB Length = 351 Score = 27.8 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 23/68 (33%), Gaps = 1/68 (1%) Query: 5 GKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQ 64 GK+V + GAG G+G AGA ++ D A + V + Sbjct: 174 GKSVAIMGAG-GLGMMLVQLARLAGASTITVFDIVPEKLELALENGADYALNSAEEGVAE 232 Query: 65 RLLAETER 72 R + Sbjct: 233 RAIELAGG 240 >6F4U-A nrPDB Length = 341 Score = 27.5 bits (60), Expect = 5.1, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 19/52 (36%) Query: 98 QTFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKA 149 + F N Q + +++ G IV + S+ + + Y KA Sbjct: 120 KLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKA 171 >6F02-A nrPDB Length = 389 Score = 27.5 bits (60), Expect = 5.1, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 19/52 (36%) Query: 98 QTFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKA 149 + F N Q + +++ G IV + S+ + + Y KA Sbjct: 122 KLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKA 173 >6BII-A nrPDB Length = 333 Score = 27.5 bits (60), Expect = 5.2, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 17/41 (41%), Gaps = 1/41 (2%) Query: 5 GKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYP 45 GK + + G G+ IG A A G ++ ++ E Sbjct: 150 GKTIGIVGFGR-IGQAIAKRAKGFGMRILYTARSRKPEAEK 189 >4LWO-B nrPDB Length = 368 Score = 27.5 bits (60), Expect = 5.2, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 30/79 (37%), Gaps = 7/79 (8%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAK-VTGFDQAFTQEQYPFATEVMDVADAAQV- 59 GK V G+G GI ++ AGAK V + + E E D++ V Sbjct: 52 SIEGKVVVDVGSGTGI---LSMWAARAGAKHVFSIEASSLSEFQIGVVEDNDLSTKITVL 108 Query: 60 AQVCQRLLAETERLDALVN 78 + ++A + VN Sbjct: 109 GDTVENIIA--GGVANFVN 125 >2HES-X nrPDB Length = 330 Score = 27.5 bits (60), Expect = 5.2, Method: Composition-based stats. Identities = 6/17 (35%), Positives = 10/17 (58%) Query: 1 MDFSGKNVWVTGAGKGI 17 ++ +GK + TG GI Sbjct: 304 LELNGKTILATGGDDGI 320 >3K92-A nrPDB Length = 424 Score = 27.5 bits (60), Expect = 5.4, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 30/91 (32%), Gaps = 15/91 (16%) Query: 1 MDFSGKNVWVTGAGKGIGYA---TALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAA 57 + + + +G G A A +AGAKV G A P ++ + D Sbjct: 217 IKLQNARIII----QGFGNAGSFLAKFMHDAGAKVIGISDANGGLYNPDGLDIPYLLDKR 272 Query: 58 QVAQVCQRLLAET--------ERLDALVNAA 80 + L + + D LV AA Sbjct: 273 DSFGMVTNLFTDVITNEELLEKDCDILVPAA 303 >4A5O-A nrPDB Length = 286 Score = 27.5 bits (60), Expect = 5.4, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 15/36 (41%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQ 37 D G + V GA +G AL + G VT + Sbjct: 158 DLYGMDAVVVGASNIVGRPMALELLLGGCTVTVTHR 193 >1NP3-A nrPDB Length = 338 Score = 27.5 bits (60), Expect = 5.9, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 24/64 (37%), Gaps = 1/64 (1%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVC 63 GK V + G G G+A A ++G VT ++ + + VAD Sbjct: 15 QGKKVAIIGYGS-QGHAHACNLKDSGVDVTVGLRSGSATVAKAEAHGLKVADVKTAVAAA 73 Query: 64 QRLL 67 ++ Sbjct: 74 DVVM 77 >3GFB-A nrPDB Length = 350 Score = 27.5 bits (60), Expect = 6.3, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 28/76 (36%), Gaps = 15/76 (19%) Query: 4 SGKNVWVTGAG--KGIGYATALA-------------FVEAGAKVTGFDQAFTQEQYPFAT 48 +G++ +TGAG +G A A A F AK G D + Sbjct: 167 AGRSTLITGAGPLGLLGIAVAKASGAYPVIVSEPSEFRRKLAKKVGADYVVNPFEEDPVK 226 Query: 49 EVMDVADAAQVAQVCQ 64 VMD+ D A V + Sbjct: 227 FVMDITDGAGVEVFLE 242 >2CWD-A nrPDB Length = 161 Score = 27.5 bits (60), Expect = 6.4, Method: Composition-based stats. Identities = 14/101 (13%), Positives = 33/101 (32%), Gaps = 9/101 (8%) Query: 23 LAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRLLAETERLDALVNAAGI 82 E GA + T+E ++ V D + +V +R ++ ++ G Sbjct: 60 RVLEEEGAYFPHVARRLTREDVLAYDHIL-VMDRENLEEVLRRFPEARGKVRLVLEELGG 118 Query: 83 LRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRG 123 + ED+++ + + + F + G Sbjct: 119 GEVQDPYYGDLEDFREV--------YWTLEAALQAFLDRHG 151 >5UZH-A nrPDB Length = 345 Score = 27.1 bits (59), Expect = 6.8, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 11/30 (36%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGF 35 K +TG G A +E G V G Sbjct: 2 KVALITGITGQDGSYLAEFLLEKGYMVYGI 31 >2BC1-A nrPDB Length = 490 Score = 27.1 bits (59), Expect = 6.8, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 25/71 (35%), Gaps = 5/71 (7%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDV----ADAAQVAQ 61 K V V GAG IG A AF G +V D T + ++ D+ + + Sbjct: 195 KRVAVVGAGY-IGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEHGIQL 253 Query: 62 VCQRLLAETER 72 + E Sbjct: 254 AFGETVKEVAG 264 >4B4V-A nrPDB Length = 303 Score = 27.1 bits (59), Expect = 7.7, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 18/35 (51%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGF 35 ++ +GK+ V G +G A+ ++A A VT Sbjct: 175 IEIAGKHAVVVGRSAILGKPMAMMLLQANATVTIC 209 >3LED-A nrPDB Length = 392 Score = 27.1 bits (59), Expect = 7.9, Method: Composition-based stats. Identities = 11/54 (20%), Positives = 19/54 (35%) Query: 174 PGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLAS 227 PG D D+ R + +E I + + +P+E +L S Sbjct: 94 PGIVDPDVMRPIIPERSNDELSILAEMAVTAAEQAIERWGKPRERIGAVLCACS 147 >6APE-A nrPDB Length = 298 Score = 27.1 bits (59), Expect = 7.9, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 19/35 (54%) Query: 1 MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGF 35 ++ GK+V + GA IG ++ + AGA V+ Sbjct: 166 IEIKGKDVAIIGASNIIGKPLSMLMLNAGASVSVC 200 >5IS8-A nrPDB Length = 381 Score = 27.1 bits (59), Expect = 8.1, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 31/77 (40%), Gaps = 4/77 (5%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGA-KVTGFDQAFTQEQYPFATEVMDVADAAQVA 60 DF K V G G GI + +AGA K+ + + + + ++ D V Sbjct: 57 DFKDKIVLDVGCGSGI---LSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVI 113 Query: 61 QVCQRLLAETERLDALV 77 ++ E++D ++ Sbjct: 114 PGKVEEVSLPEQVDIII 130 >4IKP-A nrPDB Length = 341 Score = 27.1 bits (59), Expect = 8.1, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 31/77 (40%), Gaps = 4/77 (5%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGA-KVTGFDQAFTQEQYPFATEVMDVADAAQVA 60 DF K V G G GI + +AGA K+ + + + + ++ D V Sbjct: 43 DFKDKIVLDVGCGSGI---LSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVI 99 Query: 61 QVCQRLLAETERLDALV 77 ++ E++D ++ Sbjct: 100 PGKVEEVSLPEQVDIII 116 >3B3J-A nrPDB Length = 480 Score = 27.1 bits (59), Expect = 8.1, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 31/77 (40%), Gaps = 4/77 (5%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGA-KVTGFDQAFTQEQYPFATEVMDVADAAQVA 60 DF K V G G GI + +AGA K+ + + + + ++ D V Sbjct: 156 DFKDKIVLDVGCGSGI---LSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVI 212 Query: 61 QVCQRLLAETERLDALV 77 ++ E++D ++ Sbjct: 213 PGKVEEVSLPEQVDIII 229 >3R7T-A nrPDB Length = 419 Score = 27.1 bits (59), Expect = 8.5, Method: Composition-based stats. Identities = 12/31 (38%), Positives = 14/31 (45%), Gaps = 1/31 (3%) Query: 2 DFSGKNVWVTGAGKGIGYATALAFVEAGAKV 32 GKN T GKGIG + A G +V Sbjct: 119 KLKGKNAIGT-TGKGIGPSYADKINRTGHRV 148 >2EXX-A nrPDB Length = 306 Score = 26.7 bits (58), Expect = 8.5, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 23/66 (34%), Gaps = 6/66 (9%) Query: 4 SGKNVWVTGAGKGIGYATALAFVEAG---AKVTGFD---QAFTQEQYPFATEVMDVADAA 57 K V V G G + A +E G +V + +A + + A V D Sbjct: 10 DKKLVVVFGGTGAQGGSVARTLLEDGTFKVRVVTRNPRKKAAKELRLQGAEVVQGDQDDQ 69 Query: 58 QVAQVC 63 + ++ Sbjct: 70 VIMELA 75 >1HE4-A nrPDB Length = 206 Score = 26.7 bits (58), Expect = 8.6, Method: Composition-based stats. Identities = 17/63 (26%), Positives = 25/63 (39%), Gaps = 4/63 (6%) Query: 6 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAF----TQEQYPFATEVMDVADAAQVAQ 61 K + + GA G T V+AG +VT + ++ P V DV AA V + Sbjct: 4 KKIAIFGATGQTGLTTLAQAVQAGYEVTVLVRDSSRLPSEGPRPAHVVVGDVLQAADVDK 63 Query: 62 VCQ 64 Sbjct: 64 TVA 66 >6GNF-A nrPDB Length = 544 Score = 26.7 bits (58), Expect = 8.7, Method: Composition-based stats. Identities = 10/53 (18%), Positives = 21/53 (39%), Gaps = 6/53 (11%) Query: 122 RGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSP 174 RG ++ + + ++ Y + L + + ELA G + V+P Sbjct: 17 RGSHMLNICFVSTE-----VAPYSKT-GGLGDVTEGLPEELAKIGHKVCTVAP 63 >2X3N-A nrPDB Length = 399 Score = 26.7 bits (58), Expect = 8.7, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 17/44 (38%), Gaps = 3/44 (6%) Query: 8 VWVTGAGKGIGYAT-ALAFVEAGAKVTGFDQAFTQEQYPFATEV 50 V + G GIG A A G +V +QA + A + Sbjct: 9 VLINGC--GIGGAMLAYLLGRQGHRVVVVEQARRERAINGADLL 50 >3DQQ-A nrPDB Length = 421 Score = 26.7 bits (58), Expect = 8.9, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 26/64 (40%) Query: 126 IVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQRTL 185 I AS A + A+++L + LA G+ +V+ G T + ++L Sbjct: 313 ISATASTQALAAIQQQYGATEASHAVEALFSLLAARLAEGGITRFIVAGGETSGVVTQSL 372 Query: 186 WVSD 189 ++ Sbjct: 373 GITG 376 >3IP1-A nrPDB Length = 404 Score = 26.7 bits (58), Expect = 9.7, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 20/64 (31%), Gaps = 5/64 (7%) Query: 5 GKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQ----EQYPFATEVMDVADAAQVA 60 G NV + G G IG A AGA + + A V+D V Sbjct: 214 GDNVVILGGGP-IGLAAVAILKHAGASKVILSEPSEVRRNLAKELGADHVIDPTKENFVE 272 Query: 61 QVCQ 64 V Sbjct: 273 AVLD 276 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.316 0.160 0.476 Lambda K H 0.267 0.0492 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,292,223 Number of Sequences: 36641 Number of extensions: 483016 Number of successful extensions: 3240 Number of sequences better than 10.0: 414 Number of HSP's better than 10.0 without gapping: 414 Number of HSP's successfully gapped in prelim test: 183 Number of HSP's that attempted gapping in prelim test: 1904 Number of HSP's gapped (non-prelim): 645 length of query: 248 length of database: 10,336,785 effective HSP length: 95 effective length of query: 153 effective length of database: 6,855,890 effective search space: 1048951170 effective search space used: 1048951170 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 58 (26.7 bits)