BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P14904 (514 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5JH9-A nrPDB 1059 0.0 5JM6-A nrPDB 355 2e-98 4DYO-A nrPDB 228 6e-60 3VAT-A nrPDB 224 6e-59 4OIW-A nrPDB 201 8e-52 4EME-A nrPDB 100 1e-21 2GLF-A nrPDB 90 2e-18 1Y7E-A nrPDB 89 4e-18 2GLJ-A nrPDB 86 4e-17 4MAF-A nrPDB 34 0.15 3HJ6-A nrPDB 33 0.25 4X8I-A nrPDB 33 0.37 2WZN-A nrPDB 31 1.4 5A5G-A nrPDB 30 2.0 6C90-A nrPDB 30 3.0 >5JH9-A nrPDB Length = 516 Score = 1059 bits (2739), Expect = 0.0, Method: Compositional matrix adjust. Identities = 513/514 (99%), Positives = 513/514 (99%) Query: 1 MEEQREILEQLKKTLQMLTVEPSKNNQIANEEKEKKENENSWCILEHNYEDIAQEFIDFI 60 MEEQREILEQ KKTLQMLTVEPSKNNQIANEEKEKKENENSWCILEHNYEDIAQEFIDFI Sbjct: 3 MEEQREILEQSKKTLQMLTVEPSKNNQIANEEKEKKENENSWCILEHNYEDIAQEFIDFI 62 Query: 61 YKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNW 120 YKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNW Sbjct: 63 YKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNW 122 Query: 121 RAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLL 180 RAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLL Sbjct: 123 RAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLL 182 Query: 181 YKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPDEEGNE 240 YKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPDEEGNE Sbjct: 183 YKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPDEEGNE 242 Query: 241 PPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAP 300 PPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAP Sbjct: 243 PPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAP 302 Query: 301 RLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVER 360 RLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVER Sbjct: 303 RLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVER 362 Query: 361 SSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHM 420 SSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHM Sbjct: 363 SSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHM 422 Query: 421 ATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHS 480 ATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHS Sbjct: 423 ATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHS 482 Query: 481 IRAATGSKDVGLGVKFFNGFFKHWRSVYDEFGEL 514 IRAATGSKDVGLGVKFFNGFFKHWRSVYDEFGEL Sbjct: 483 IRAATGSKDVGLGVKFFNGFFKHWRSVYDEFGEL 516 >5JM6-A nrPDB Length = 519 Score = 355 bits (911), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 194/473 (41%), Positives = 280/473 (59%), Gaps = 18/473 (3%) Query: 50 EDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGT 109 E Q ++DF+ NPT +HVV + + L K + L + +W + GGK++T RNG+ Sbjct: 52 EHFTQPYLDFMTHNPTVFHVVDYCKQKLLKAGYVELPARDSWTGKL-VPGGKYFTTRNGS 110 Query: 110 NLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWL 169 ++ AF +G+ ++ G+ +I H+DALT +LKP S K T EGY ++ VA Y G LNE W Sbjct: 111 SIIAFTVGQAYKPGNGIAMIAGHIDALTARLKPTSVKPTKEGYVQLGVAQYAGALNETWW 170 Query: 170 DRDLGIGGRLLYK--KKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIP 227 DRDL +GGR++ K K G +K VD PV RIP+LAPHFG G ++E + +P Sbjct: 171 DRDLSVGGRVIVKDPKTGKTTVKLVKVD---WPVARIPTLAPHFGIGMTGHGNRETEMVP 227 Query: 228 VIGFPTPDEEGNEPPTDDEKKSP--LFGKHCIHLLRYVAKLAGV-EVSELIQMDLDLFDV 284 VIG D G + ++ P L++ + G+ + ++ +L+LFD Sbjct: 228 VIGIDNSDLLGEKAESEKPVGKPGSFASTQPPKLVKLILSQLGLSDPDSILNWELELFDA 287 Query: 285 QKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSL 344 Q T+GG+ K F+FA R+DD+LCS+AA +AL+ +AK T+ + V L+D+EEIGSL Sbjct: 288 QPATVGGLDKEFIFAGRIDDKLCSWAAFMALL-HAKRAPTD--GVIKLVALFDDEEIGSL 344 Query: 345 TRQGAKGGLLESVVER------SSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVY 398 RQGA+G L +ER SS++ P L +A S ++S+DV H +PNF + Sbjct: 345 LRQGARGNFLPITIERILESFCSSNSVPFGPGILGQTYARSFLVSSDVTHAAHPNFTQTN 404 Query: 399 LKNHFPVPNVGITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGP 458 L H P NVG+ L +D + HM TD V A+++ +A +G Q I+N+SRSGGT+GP Sbjct: 405 LPGHSPRLNVGVALCVDASAHMTTDSVSMAILDRIAELSGCVNQRHMIRNDSRSGGTVGP 464 Query: 459 SLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFFKHWRSVYDEF 511 L++ G + D+GI QLSMHSIRA TGS D GLGVKF+ GF W V E+ Sbjct: 465 MLSAAMGVKAADVGIPQLSMHSIRAMTGSLDPGLGVKFYKGFLDFWEEVDLEW 517 >4DYO-A nrPDB Length = 485 Score = 228 bits (580), Expect = 6e-60, Method: Compositional matrix adjust. Identities = 150/496 (30%), Positives = 244/496 (49%), Gaps = 36/496 (7%) Query: 27 QIANEEKEKKENENSWCILEHNYEDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLS 86 Q+A K +KE + A+E + F+ ++P+ +H V+ L + F L Sbjct: 12 QVAMNGKARKEA----------VQTAAKELLKFVNRSPSPFHAVAECRNRLLQAGFSELK 61 Query: 87 EKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFK 146 E W + K++ RN + + AF +G + G +IG+H D+ +++K S + Sbjct: 62 ETEKWNI---KPESKYFMTRNSSTIIAFAVGGQYVPGNGFSLIGAHTDSPCLRVKRRS-R 117 Query: 147 DTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPS 206 + G+ ++ V YGG + W DRDL + GR++ K + ++ LV P+ RIP Sbjct: 118 RSQVGFQQVGVETYGGGIWSTWFDRDLTLAGRVIVKCPTSGRLEQQLVH-VERPILRIPH 176 Query: 207 LAPHFGKPAEGPF--DKEDQTIPVIGFPTPDE--EGNEPP-----TDDEKKSPLFGKHCI 257 LA H + F + E +P++ +E +G P D+ S L C Sbjct: 177 LAIHLQRNINENFGPNTEMHLVPILATAIQEELEKGTPEPGPLNAVDERHHSVLMSLLCA 236 Query: 258 HLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALI- 316 HL G+ ++++M+L L D Q +GG F+FAPRLD+ F A+ ALI Sbjct: 237 HL--------GLSPKDIVEMELCLADTQPAVLGGAYDEFIFAPRLDNLHSCFCALQALID 288 Query: 317 -CYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVERSSSAFTKKPVDLHTV 375 C E + VTLYDNEE+GS + QGA+ LL +V R SA + P Sbjct: 289 SCAGPGSLATEPHV-RMVTLYDNEEVGSESAQGAQS-LLTELVLRRISASCQHPTAFEEA 346 Query: 376 WANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHMATDVVGTALVEELAR 435 S ++SAD+ H +PN+ + + +NH P+ + G + ++ A++ V AL+ E+A Sbjct: 347 IPKSFMISADMAHAVHPNYLDKHEENHRPLFHKGPVIKVNSKQRYASNAVSEALIREVAN 406 Query: 436 RNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVK 495 + +Q ++N++ G TIGP LAS+ G R +DLG QL+MHSIR + V + Sbjct: 407 KVKVPLQDLMVRNDTPCGTTIGPILASRLGLRVLDLGSPQLAMHSIREMACTTGVLQTLT 466 Query: 496 FFNGFFKHWRSVYDEF 511 F GFF+ + S+ + Sbjct: 467 LFKGFFELFPSLAENL 482 >3VAT-A nrPDB Length = 496 Score = 224 bits (572), Expect = 6e-59, Method: Compositional matrix adjust. Identities = 145/466 (31%), Positives = 237/466 (50%), Gaps = 26/466 (5%) Query: 53 AQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLS 112 A+E + F+ ++P+ +H V+ L + F L E +W + K++ RN + + Sbjct: 39 ARELLKFVNRSPSPFHAVAECRSRLLQAGFHELKETESWDI---KPESKYFLTRNSSTII 95 Query: 113 AFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRD 172 AF +G + G +IG+H D+ +++K S + + G+ ++ V YGG + W DRD Sbjct: 96 AFAVGGQYVPGNGFSLIGAHTDSPCLRVKRRS-RRSQVGFQQVGVETYGGGIWSTWFDRD 154 Query: 173 LGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPF--DKEDQTIPVIG 230 L + GR++ K + ++ LV P+ RIP LA H + F + E +P++ Sbjct: 155 LTLAGRVIVKCPTSGRLEQRLVH-VDRPILRIPHLAIHLQRNVNENFGPNMEMHLVPILA 213 Query: 231 FPTPDE--EGNEPP-----TDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFD 283 +E +G P TD+ S L C HL G+ ++++M+L L D Sbjct: 214 TSIQEELEKGTPEPGPLNATDERHHSVLTSLLCAHL--------GLSPEDILEMELCLAD 265 Query: 284 VQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALI--CYAKDVNTEESDLFSTVTLYDNEEI 341 Q +GG + F+FAPRLD+ F A+ ALI C A + + + LYDNEE+ Sbjct: 266 TQPAVLGGAYEEFIFAPRLDNLHSCFCALQALIDSCSAPASLAADPHV-RMIALYDNEEV 324 Query: 342 GSLTRQGAKGGLLESVVERSSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKN 401 GS + QGA+ LL +V R SA + S ++SAD+ H +PN+ + + +N Sbjct: 325 GSESAQGAQS-LLTELVLRRISASPQHLTAFEEAIPKSYMISADMAHAVHPNYLDKHEEN 383 Query: 402 HFPVPNVGITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLA 461 H P+ + G + ++ A++ V AL+ E+A G +Q ++N+S G TIGP LA Sbjct: 384 HRPLFHKGPVIKVNSKQRYASNAVSEALIREVASSVGVPLQDLMVRNDSPCGTTIGPILA 443 Query: 462 SQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFFKHWRSV 507 S+ G R +DLG QL+MHSIR + V + F GFF+ + S+ Sbjct: 444 SRLGLRVLDLGSPQLAMHSIRETACTTGVLQTITLFKGFFELFPSL 489 >4OIW-A nrPDB Length = 431 Score = 201 bits (510), Expect = 8e-52, Method: Compositional matrix adjust. Identities = 135/456 (29%), Positives = 220/456 (48%), Gaps = 41/456 (8%) Query: 51 DIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTN 110 ++ Q IDF+ +PT +H + A L+ ++ L E+ W E GG++Y RN ++ Sbjct: 6 ELNQGLIDFLKASPTPFHATASLARRLEAAGYRRLDERDAWHT---ETGGRYYVTRNDSS 62 Query: 111 LSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLD 170 L A LG+ E G ++G+ D+ +++KP + + G+ ++ V YGG L W D Sbjct: 63 LIAIRLGRRSPLESGFRLVGAATDSPCLRVKP-NPEIARNGFLQLGVEVYGGALFAPWFD 121 Query: 171 RDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPA-EG-PFDKEDQTIPV 228 RDL + GR+ ++ G +++S LVD + IP+LA H + A EG P + +++ P+ Sbjct: 122 RDLSLAGRVTFRANG--KLESRLVDFRK-AIAVIPNLAIHLNRAANEGWPINAQNELPPI 178 Query: 229 IGFPTPDEEGNEPPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGT 288 I P E + DE+ L +H G+ ++ +L +D Q Sbjct: 179 IAQLAPGEAADFRLLLDEQ---LLREH------------GITADVVLDYELSFYDTQSAA 223 Query: 289 IGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQG 348 + G+ F+ RLD+ L A + AL+ E D + D+EE+GS + G Sbjct: 224 VVGLNDEFIAGARLDNLLSCHAGLEALL-------NAEGDENCILVCTDHEEVGSCSHCG 276 Query: 349 AKGGLLESVVER---SSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPV 405 A G LE V+ R AF++ S+++SAD H +PN+ + + NH P Sbjct: 277 ADGPFLEQVLRRLLPEGDAFSR-------AIQRSLLVSADNAHGVHPNYADRHDANHGPA 329 Query: 406 PNVGITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTG 465 N G + ++ N AT+ L + + VQ F +++ G TIGP ASQ G Sbjct: 330 LNGGPVIKINSNQRYATNSETAGFFRHLCQDSEVPVQSFVTRSDMGCGSTIGPITASQVG 389 Query: 466 ARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFF 501 RT+D+G+ +MHSIR GS D+ VK F+ Sbjct: 390 VRTVDIGLPTFAMHSIRELAGSHDLAHLVKVLGAFY 425 >4EME-A nrPDB Length = 571 Score = 100 bits (250), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 76/284 (26%), Positives = 132/284 (46%), Gaps = 36/284 (12%) Query: 259 LLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAPRLDDRL---CSFAAMIAL 315 LL ++K + +++ +L L D Q+ G+ + F+ R D+ L C F I L Sbjct: 281 LLYLLSKELNCKEEDILDFELCLMDTQEPCFTGVYEEFIEGARFDNLLGSFCVFEGFIEL 340 Query: 316 ICYAKD-----------------VNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVV 358 + K+ + ++L+ ++ YD+EEIGSL+ GA+ ++ + Sbjct: 341 VNSIKNHTSNENTNHTNNITNDINDNIHNNLYISIG-YDHEEIGSLSEVGARSYCTKNFI 399 Query: 359 ERS-SSAFTK----KPVDLHTVWAN----SIILSADVNHLYNPNFPEVYLKNHFPVPNVG 409 +R SS F K K + + ++ N S IL+ D+ H +PN+PE NH + G Sbjct: 400 DRIISSVFKKEIHEKNLSVQEIYGNLVNRSFILNVDMAHCSHPNYPETVQDNHQLFFHEG 459 Query: 410 ITLSLDPNGHMATDVVGTALVEEL------ARRNGDKVQYFQIKNNSRSGGTIGPSLASQ 463 I + + N + T + +L++ + K Q F +KN++ G T+G +A+ Sbjct: 460 IAIKYNTNKNYVTSPLHASLIKRTFELYYNKYKQQIKYQNFMVKNDTPCGSTVGSMVAAN 519 Query: 464 TGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFFKHWRSV 507 ID+GI QL+MHSIR DV +K F+ ++ V Sbjct: 520 LSMPGIDIGIPQLAMHSIREIAAVHDVFFLIKGVFAFYTYYNQV 563 Score = 65.9 bits (159), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 50/183 (27%), Positives = 86/183 (46%), Gaps = 12/183 (6%) Query: 53 AQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLS 112 AQ+ + FI ++ + + E L+ + F LSE W ++ ++ G + + N+ Sbjct: 10 AQDALKFIQRSGSNFLACKNLKERLENNGFINLSEGETW--NLNKNEG-YVLCKENRNIC 66 Query: 113 AFILGKNWRAEKGVGVIG-SHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDR 171 F +GKN+ + G +I H+D+ +K+ P + + +I V YG L W DR Sbjct: 67 GFFVGKNFNIDTGSILISIGHIDSCALKISPNN-NVIKKKIHQINVECYGSGLWHTWFDR 125 Query: 172 DLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPF----DKEDQTIP 227 LG+ G++LYKK N++ L+ V +PSLA H F + E+ P Sbjct: 126 SLGLSGQVLYKK--GNKLVEKLIQINK-SVLFLPSLAIHLQNRTRYDFSVKINYENHIKP 182 Query: 228 VIG 230 +I Sbjct: 183 IIS 185 >2GLF-A nrPDB Length = 450 Score = 90.1 bits (222), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 114/460 (24%), Positives = 200/460 (43%), Gaps = 48/460 (10%) Query: 35 KKENENSWCILE-HNYEDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQD 93 K E +N W + E ++E+++F+ K T V +LD+ F L +D Sbjct: 1 KMERKNVWHHRKKEEIEAFSKEYMEFMSKAKTERMTVKEIKRILDESGFVPL------ED 54 Query: 94 SIGEDGG-KFYTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGY 152 G+ Y + G ++AF + + + +G+ ++ +H+D+ + KP + E Sbjct: 55 FAGDPMNMTVYAVNRGKAIAAFRVVDDLK--RGLNLVVAHIDSPRLDFKPNPLIED-EQI 111 Query: 153 GRIAVAPYGGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFG 212 YGG WL L I G +L+K GT EI+ + D PV IP L PH Sbjct: 112 ALFKTHYYGGIKKYHWLSIPLEIHG-VLFKNDGT-EIEIHIGDKPEDPVFTIPDLLPHL- 168 Query: 213 KPAEGPFDKEDQTIP--VIGFPTPDEEGNEPPTDDEKKSPLFGKHCIHLLRYVAKLAGVE 270 DKED I G G P + +EK++ ++L+ + ++ G+ Sbjct: 169 -------DKEDAKISEKFKGENLMLIAGTIPLSGEEKEAV-----KTNVLKILNEMYGIT 216 Query: 271 VSELIQMDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDLF 330 + + ++++ G+ + + A DDR+C++ A+ AL+ N E+S Sbjct: 217 EEDFVSGEIEVVPAFSPREVGMDRSLIGAYGQDDRICAYTALRALLS----ANPEKS--- 269 Query: 331 STVTLYDNEEIGSLTRQGAKGGL----LESVVERSSSAFTKKPVDLHTVWANSIILSADV 386 V +D EEIGS GAK L +++ + ++ +D V N+ ++S DV Sbjct: 270 IGVIFFDKEEIGSDGNTGAKARFYLKALRQILKMQGAKDSEFVLD--EVLENTSVISGDV 327 Query: 387 NHLYNPNFPEVYLKNHFPVPNVGITLS--LDPNGHMATDVVGTALVEELARRNGDKVQYF 444 NP + +V+ ++ P G+ L G +T+ V + + ++ + Sbjct: 328 CAAVNPPYKDVHDLHNAPKLGYGVALVKYTGARGKYSTNDAHAEFVARVRKVLNEQGVIW 387 Query: 445 QI----KNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHS 480 Q+ K + GGTI A + G+ ID+G A L MHS Sbjct: 388 QVATLGKVDQGGGGTIAKFFAER-GSDVIDMGPALLGMHS 426 >1Y7E-A nrPDB Length = 458 Score = 89.4 bits (220), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 124/488 (25%), Positives = 192/488 (39%), Gaps = 56/488 (11%) Query: 39 ENSWCILEHNYED----IAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQ-- 92 +N W L ++ ++ + FI K T V ++ + K F EK N Sbjct: 4 QNPWIYLNEEEKNQILNFSESYKKFISKFKTEREVTAYALDKAKKLGFINAEEKKNLMPG 63 Query: 93 DSIGEDGGKFYTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGY 152 D I FYT R + ++ I+GKN E G+ I SH D+ + KP + E Sbjct: 64 DKI------FYTCREKS-VAFAIIGKN-PIEDGMNFIVSHTDSPRLDAKPSPISEENE-L 114 Query: 153 GRIAVAPYGGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHF- 211 I YGG WL L I G + K EI + D+ PV IP + PH Sbjct: 115 TFIKTNYYGGIKKYQWLSTPLSIRGVVFLKNGEKVEIN--IGDNENDPVFVIPDILPHLD 172 Query: 212 -----GKPAEGPFDKEDQTIPVIGFPTPDEEGNEPPTDDEKKSPLFGKHCIHLLRYVAKL 266 K ++ + E+ I + P +E N K + L+ + + Sbjct: 173 RKIQRNKKSDEIVEGENLKILIGSLPIETKEKN--------------KVKLATLQLIKEK 218 Query: 267 AGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEE 326 +E + + ++++ G K + A DD++C F ++ ++ + N Sbjct: 219 YKIEEEDFVSSEIEIVPAGTAKDVGFDKALIGAYGQDDKICVFTSLESIFDLEETPNKT- 277 Query: 327 SDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVERSSSAFTKKPVD-LHT---VWANSIIL 382 + L D EEIGS G LE V K + LH +W NS + Sbjct: 278 ----AICFLVDKEEIGSTGSTGLDSRYLEYFVSDMIFKIKKSEYNNLHVQKALW-NSKSI 332 Query: 383 SADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGH----MATDVVG--TALVEELARR 436 SADV NP F V+ + + P GI + + GH MA+D + + +L + Sbjct: 333 SADVCAAINPLFSSVHDEQNAPQLGYGIPI-MKYTGHGGKSMASDADAELVSYIRQLLNK 391 Query: 437 NGDKVQYFQI-KNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVK 495 N Q + K GGT+ LA G RTID+G A +SMHS T D+ Sbjct: 392 NNIAWQVATLGKVEEGGGGTVAKFLAGY-GIRTIDMGPAVISMHSPMEITSKFDLYNAYL 450 Query: 496 FFNGFFKH 503 + F++ Sbjct: 451 AYKAFYRE 458 >2GLJ-A nrPDB Length = 461 Score = 85.9 bits (211), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 108/467 (23%), Positives = 194/467 (41%), Gaps = 53/467 (11%) Query: 36 KENENSWCILEHNYED--------IAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSE 87 KE +N+W Y+D + F +FI T V+ + +K ++ + + Sbjct: 3 KEYKNAW----DKYDDKQLKEVFALGDRFKNFISNCKTERECVTELIKTAEKSGYRNIED 58 Query: 88 KSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDA--LTVKLKPVSF 145 +++ E G K Y G L F++GK G ++G+H+D+ L +K P+ + Sbjct: 59 ILAKGETLKE-GDKVYANNRGKGLIMFLIGKE-PLYTGFKILGAHIDSPRLDLKQNPL-Y 115 Query: 146 KDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIP 205 +DT + YGG W+ L I G ++ KK GT + + + PV + Sbjct: 116 EDT--DLAMLETHYYGGIKKYQWVTLPLAIHG-VIVKKDGTI-VNVCVGEDDNDPVFGVS 171 Query: 206 SLAPHFG-----KPAEGPFDKEDQTIPVIGFPTPDEEGNEPPTDDEKKSPLFGKHCIHLL 260 + H K A + ED I + G+ P D E+K + KH +++ Sbjct: 172 DILVHLASEQLEKKASKVIEGEDLNILI---------GSIPLKDGEEKQKV--KH--NIM 218 Query: 261 RYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAK 320 + + + + + + +L++ K G + + DDR+C++ + A++ Sbjct: 219 KILNEKYDISEEDFVSAELEIVPAGKARDYGFDRSMVMGYGQDDRICAYTSFEAML---- 274 Query: 321 DVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLE-SVVERSSSAFTKKPVDLHTVWANS 379 + + L D EE+GS+ G + E +V + S + L NS Sbjct: 275 --EMKNAKKTCITILVDKEEVGSIGATGMQSKFFENTVADIMSLCGDYDELKLRKALYNS 332 Query: 380 IILSADVNHLYNPNFPEVYLKNHFPVPNVGITLS--LDPNGHMATDVVGTALVEELARRN 437 +LS+DV+ ++PN+P V K + GI + G + + EL R Sbjct: 333 EMLSSDVSAAFDPNYPNVMEKRNSAYLGKGIVFNKYTGSRGKSGCNDANPEYIAELRRIL 392 Query: 438 GDKVQYFQI----KNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHS 480 + +Q K + GGTI LA + G + ID G+A L+MH+ Sbjct: 393 SKESVNWQTAELGKVDQGGGGTIAYILA-EYGMQVIDCGVALLNMHA 438 >4MAF-A nrPDB Length = 404 Score = 34.3 bits (77), Expect = 0.15, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 5/68 (7%) Query: 427 TALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQ--LSMHSIRAA 484 T L E RRN D V FQ++N +G + L + T R +++G L +H + Sbjct: 181 TQLRAEFTRRNADAVFAFQLRNPVHNGHAL---LMTDTRKRLLEMGYKNPVLLLHPLGGY 237 Query: 485 TGSKDVGL 492 T + DV L Sbjct: 238 TKADDVPL 245 >3HJ6-A nrPDB Length = 327 Score = 33.5 bits (75), Expect = 0.25, Method: Compositional matrix adjust. Identities = 19/73 (26%), Positives = 34/73 (46%), Gaps = 15/73 (20%) Query: 351 GGLLESVVERSSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGI 410 G++E ++ R+ F K +D D HL+ P+ PE Y+K + + + Sbjct: 196 AGVVEEIISRAD--FVKPSLD-------------DARHLFGPDSPENYVKRYLELGVKAV 240 Query: 411 TLSLDPNGHMATD 423 L+L G +A+D Sbjct: 241 ILTLGEEGVIASD 253 >4X8I-A nrPDB Length = 346 Score = 32.7 bits (73), Expect = 0.37, Method: Compositional matrix adjust. Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 13/92 (14%) Query: 287 GTIG-------GIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNE 339 GTIG + +H P LDDR+C + A+I A+ + E+D++ ++ E Sbjct: 154 GTIGEFAPNFTRLSEHRFATPYLDDRICLY----AMIEAARQLGEHEADIYIVASV--QE 207 Query: 340 EIGSLTRQGAKGGLLESVVERSSSAFTKKPVD 371 EIG + A + V F K+P D Sbjct: 208 EIGLRGARVASFAIDPEVGIAMDVTFAKQPND 239 >2WZN-A nrPDB Length = 354 Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust. Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 6/80 (7%) Query: 292 IGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKG 351 + +H P LDDR+C + A+I A+ + E+D++ ++ EE+G + A Sbjct: 174 LNEHRFATPYLDDRICLY----AMIEAARQLGDHEADIYIVGSV--QEEVGLRGARVASY 227 Query: 352 GLLESVVERSSSAFTKKPVD 371 + V F K+P D Sbjct: 228 AINPEVGIAMDVTFAKQPHD 247 >5A5G-A nrPDB Length = 558 Score = 30.4 bits (67), Expect = 2.0, Method: Compositional matrix adjust. Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 6/87 (6%) Query: 279 LDLFDVQ-KGTIGGIGKHFLFAPRLDDRLCSFAA-MIALICYAKDVNTEESDLFSTVTLY 336 +D+ D Q + I G+G PR D + A+ ++A+ C A D+ + L V Y Sbjct: 165 VDINDRQLRFVIDGLGGKANGVPREDGFDITVASEVMAIFCLANDIMDLKERLAKIVVAY 224 Query: 337 DNE----EIGSLTRQGAKGGLLESVVE 359 D E G L QGA LL+ ++ Sbjct: 225 DREGKPVTAGDLKAQGAMAALLKDALK 251 >6C90-A nrPDB Length = 734 Score = 29.6 bits (65), Expect = 3.0, Method: Compositional matrix adjust. Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 8/70 (11%) Query: 390 YNPNFPEVYLKNHFPVPNVGITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNN 449 Y P + Y+ FP G+ L +D NG D TA+ ++ R GD + Q Sbjct: 244 YRPTPLQHYI---FPAGGDGLHLVVDENGDFREDNFNTAM--QVLRDAGDLAKGDQ---K 295 Query: 450 SRSGGTIGPS 459 R GGT GPS Sbjct: 296 GRKGGTKGPS 305 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5JH9-A nrPDB 735 0.0 4DYO-A nrPDB 570 e-163 3VAT-A nrPDB 556 e-159 5JM6-A nrPDB 543 e-155 4OIW-A nrPDB 483 e-137 2GLJ-A nrPDB 440 e-124 2GLF-A nrPDB 439 e-124 1Y7E-A nrPDB 434 e-122 4EME-A nrPDB 272 2e-73 Sequences not found previously or not previously below threshold: 4X8I-A nrPDB 61 1e-09 2WZN-A nrPDB 60 2e-09 4WWV-A nrPDB 46 5e-05 1VHO-A nrPDB 44 1e-04 1Y0Y-A nrPDB 42 7e-04 5DS0-A nrPDB 41 0.002 1VHE-A nrPDB 37 0.018 5NE9-A nrPDB 36 0.061 2EC6-A nrPDB 32 0.53 1ZMR-A nrPDB 32 0.87 5UM0-A nrPDB 31 1.1 4NG4-A nrPDB 30 2.1 1ZOF-A nrPDB 30 2.1 >5JH9-A nrPDB Length = 516 Score = 735 bits (1897), Expect = 0.0, Method: Composition-based stats. Identities = 513/514 (99%), Positives = 513/514 (99%) Query: 1 MEEQREILEQLKKTLQMLTVEPSKNNQIANEEKEKKENENSWCILEHNYEDIAQEFIDFI 60 MEEQREILEQ KKTLQMLTVEPSKNNQIANEEKEKKENENSWCILEHNYEDIAQEFIDFI Sbjct: 3 MEEQREILEQSKKTLQMLTVEPSKNNQIANEEKEKKENENSWCILEHNYEDIAQEFIDFI 62 Query: 61 YKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNW 120 YKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNW Sbjct: 63 YKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNW 122 Query: 121 RAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLL 180 RAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLL Sbjct: 123 RAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLL 182 Query: 181 YKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPDEEGNE 240 YKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPDEEGNE Sbjct: 183 YKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPDEEGNE 242 Query: 241 PPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAP 300 PPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAP Sbjct: 243 PPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAP 302 Query: 301 RLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVER 360 RLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVER Sbjct: 303 RLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVER 362 Query: 361 SSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHM 420 SSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHM Sbjct: 363 SSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHM 422 Query: 421 ATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHS 480 ATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHS Sbjct: 423 ATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHS 482 Query: 481 IRAATGSKDVGLGVKFFNGFFKHWRSVYDEFGEL 514 IRAATGSKDVGLGVKFFNGFFKHWRSVYDEFGEL Sbjct: 483 IRAATGSKDVGLGVKFFNGFFKHWRSVYDEFGEL 516 >4DYO-A nrPDB Length = 485 Score = 570 bits (1468), Expect = e-163, Method: Composition-based stats. Identities = 150/496 (30%), Positives = 244/496 (49%), Gaps = 36/496 (7%) Query: 27 QIANEEKEKKENENSWCILEHNYEDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLS 86 Q+A K +KE + A+E + F+ ++P+ +H V+ L + F L Sbjct: 12 QVAMNGKARKEA----------VQTAAKELLKFVNRSPSPFHAVAECRNRLLQAGFSELK 61 Query: 87 EKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFK 146 E W + K++ RN + + AF +G + G +IG+H D+ +++K S + Sbjct: 62 ETEKWNI---KPESKYFMTRNSSTIIAFAVGGQYVPGNGFSLIGAHTDSPCLRVKRRS-R 117 Query: 147 DTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPS 206 + G+ ++ V YGG + W DRDL + GR++ K + ++ LV P+ RIP Sbjct: 118 RSQVGFQQVGVETYGGGIWSTWFDRDLTLAGRVIVKCPTSGRLEQQLVH-VERPILRIPH 176 Query: 207 LAPHFGKPAEGPF--DKEDQTIPVIGFPTPDE--EGNEPP-----TDDEKKSPLFGKHCI 257 LA H + F + E +P++ +E +G P D+ S L C Sbjct: 177 LAIHLQRNINENFGPNTEMHLVPILATAIQEELEKGTPEPGPLNAVDERHHSVLMSLLCA 236 Query: 258 HLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALI- 316 HL G+ ++++M+L L D Q +GG F+FAPRLD+ F A+ ALI Sbjct: 237 HL--------GLSPKDIVEMELCLADTQPAVLGGAYDEFIFAPRLDNLHSCFCALQALID 288 Query: 317 -CYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVERSSSAFTKKPVDLHTV 375 C E + VTLYDNEE+GS + QGA+ LL +V R SA + P Sbjct: 289 SCAGPGSLATEPHV-RMVTLYDNEEVGSESAQGAQS-LLTELVLRRISASCQHPTAFEEA 346 Query: 376 WANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHMATDVVGTALVEELAR 435 S ++SAD+ H +PN+ + + +NH P+ + G + ++ A++ V AL+ E+A Sbjct: 347 IPKSFMISADMAHAVHPNYLDKHEENHRPLFHKGPVIKVNSKQRYASNAVSEALIREVAN 406 Query: 436 RNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVK 495 + +Q ++N++ G TIGP LAS+ G R +DLG QL+MHSIR + V + Sbjct: 407 KVKVPLQDLMVRNDTPCGTTIGPILASRLGLRVLDLGSPQLAMHSIREMACTTGVLQTLT 466 Query: 496 FFNGFFKHWRSVYDEF 511 F GFF+ + S+ + Sbjct: 467 LFKGFFELFPSLAENL 482 >3VAT-A nrPDB Length = 496 Score = 556 bits (1432), Expect = e-159, Method: Composition-based stats. Identities = 145/478 (30%), Positives = 239/478 (50%), Gaps = 26/478 (5%) Query: 45 LEHNYEDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYT 104 + + A+E + F+ ++P+ +H V+ L + F L E +W + K++ Sbjct: 31 RKEAVQAAARELLKFVNRSPSPFHAVAECRSRLLQAGFHELKETESWDI---KPESKYFL 87 Query: 105 IRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTL 164 RN + + AF +G + G +IG+H D+ +++K S + + G+ ++ V YGG + Sbjct: 88 TRNSSTIIAFAVGGQYVPGNGFSLIGAHTDSPCLRVKRRS-RRSQVGFQQVGVETYGGGI 146 Query: 165 NELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPF--DKE 222 W DRDL + GR++ K + ++ LV P+ RIP LA H + F + E Sbjct: 147 WSTWFDRDLTLAGRVIVKCPTSGRLEQRLVH-VDRPILRIPHLAIHLQRNVNENFGPNME 205 Query: 223 DQTIPVIGFPTPDE--EGNEPP-----TDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELI 275 +P++ +E +G P TD+ S L C HL G+ +++ Sbjct: 206 MHLVPILATSIQEELEKGTPEPGPLNATDERHHSVLTSLLCAHL--------GLSPEDIL 257 Query: 276 QMDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALI--CYAKDVNTEESDLFSTV 333 +M+L L D Q +GG + F+FAPRLD+ F A+ ALI C A + + + Sbjct: 258 EMELCLADTQPAVLGGAYEEFIFAPRLDNLHSCFCALQALIDSCSAPASLAADPHV-RMI 316 Query: 334 TLYDNEEIGSLTRQGAKGGLLESVVERSSSAFTKKPVDLHTVWANSIILSADVNHLYNPN 393 LYDNEE+GS + QGA+ LL +V R SA + S ++SAD+ H +PN Sbjct: 317 ALYDNEEVGSESAQGAQS-LLTELVLRRISASPQHLTAFEEAIPKSYMISADMAHAVHPN 375 Query: 394 FPEVYLKNHFPVPNVGITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNNSRSG 453 + + + +NH P+ + G + ++ A++ V AL+ E+A G +Q ++N+S G Sbjct: 376 YLDKHEENHRPLFHKGPVIKVNSKQRYASNAVSEALIREVASSVGVPLQDLMVRNDSPCG 435 Query: 454 GTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFFKHWRSVYDEF 511 TIGP LAS+ G R +DLG QL+MHSIR + V + F GFF+ + S+ Sbjct: 436 TTIGPILASRLGLRVLDLGSPQLAMHSIRETACTTGVLQTITLFKGFFELFPSLSRSL 493 >5JM6-A nrPDB Length = 519 Score = 543 bits (1399), Expect = e-155, Method: Composition-based stats. Identities = 192/471 (40%), Positives = 277/471 (58%), Gaps = 14/471 (2%) Query: 50 EDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGT 109 E Q ++DF+ NPT +HVV + + L K + L + +W + GGK++T RNG+ Sbjct: 52 EHFTQPYLDFMTHNPTVFHVVDYCKQKLLKAGYVELPARDSWTGKL-VPGGKYFTTRNGS 110 Query: 110 NLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWL 169 ++ AF +G+ ++ G+ +I H+DALT +LKP S K T EGY ++ VA Y G LNE W Sbjct: 111 SIIAFTVGQAYKPGNGIAMIAGHIDALTARLKPTSVKPTKEGYVQLGVAQYAGALNETWW 170 Query: 170 DRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVI 229 DRDL +GGR++ K T + LV PV RIP+LAPHFG G ++E + +PVI Sbjct: 171 DRDLSVGGRVIVKDPKTGKTTVKLV-KVDWPVARIPTLAPHFGIGMTGHGNRETEMVPVI 229 Query: 230 GFPTPDEEGNEPPTDDEKKSP--LFGKHCIHLLRYVAKLAGVE-VSELIQMDLDLFDVQK 286 G D G + ++ P L++ + G+ ++ +L+LFD Q Sbjct: 230 GIDNSDLLGEKAESEKPVGKPGSFASTQPPKLVKLILSQLGLSDPDSILNWELELFDAQP 289 Query: 287 GTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTR 346 T+GG+ K F+FA R+DD+LCS+AA +AL+ +AK T+ + V L+D+EEIGSL R Sbjct: 290 ATVGGLDKEFIFAGRIDDKLCSWAAFMALL-HAKRAPTD--GVIKLVALFDDEEIGSLLR 346 Query: 347 QGAKGGLLESVVER------SSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLK 400 QGA+G L +ER SS++ P L +A S ++S+DV H +PNF + L Sbjct: 347 QGARGNFLPITIERILESFCSSNSVPFGPGILGQTYARSFLVSSDVTHAAHPNFTQTNLP 406 Query: 401 NHFPVPNVGITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSL 460 H P NVG+ L +D + HM TD V A+++ +A +G Q I+N+SRSGGT+GP L Sbjct: 407 GHSPRLNVGVALCVDASAHMTTDSVSMAILDRIAELSGCVNQRHMIRNDSRSGGTVGPML 466 Query: 461 ASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFFKHWRSVYDEF 511 ++ G + D+GI QLSMHSIRA TGS D GLGVKF+ GF W V E+ Sbjct: 467 SAAMGVKAADVGIPQLSMHSIRAMTGSLDPGLGVKFYKGFLDFWEEVDLEW 517 >4OIW-A nrPDB Length = 431 Score = 483 bits (1244), Expect = e-137, Method: Composition-based stats. Identities = 129/453 (28%), Positives = 212/453 (46%), Gaps = 35/453 (7%) Query: 51 DIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTN 110 ++ Q IDF+ +PT +H + A L+ ++ L E+ W E GG++Y RN ++ Sbjct: 6 ELNQGLIDFLKASPTPFHATASLARRLEAAGYRRLDERDAWHT---ETGGRYYVTRNDSS 62 Query: 111 LSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLD 170 L A LG+ E G ++G+ D+ +++KP + G+ ++ V YGG L W D Sbjct: 63 LIAIRLGRRSPLESGFRLVGAATDSPCLRVKPNP-EIARNGFLQLGVEVYGGALFAPWFD 121 Query: 171 RDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEG--PFDKEDQTIPV 228 RDL + GR+ ++ G +++S LVD + IP+LA H + A P + +++ P+ Sbjct: 122 RDLSLAGRVTFRANG--KLESRLVDFRK-AIAVIPNLAIHLNRAANEGWPINAQNELPPI 178 Query: 229 IGFPTPDEEGNEPPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGT 288 I P E + DE+ + + G+ ++ +L +D Q Sbjct: 179 IAQLAPGEAADFRLLLDEQ---------------LLREHGITADVVLDYELSFYDTQSAA 223 Query: 289 IGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQG 348 + G+ F+ RLD+ L A + AL+ E D + D+EE+GS + G Sbjct: 224 VVGLNDEFIAGARLDNLLSCHAGLEALL-------NAEGDENCILVCTDHEEVGSCSHCG 276 Query: 349 AKGGLLESVVERSSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNV 408 A G LE V+ R S+++SAD H +PN+ + + NH P N Sbjct: 277 ADGPFLEQVLRRLLPEGD----AFSRAIQRSLLVSADNAHGVHPNYADRHDANHGPALNG 332 Query: 409 GITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGART 468 G + ++ N AT+ L + + VQ F +++ G TIGP ASQ G RT Sbjct: 333 GPVIKINSNQRYATNSETAGFFRHLCQDSEVPVQSFVTRSDMGCGSTIGPITASQVGVRT 392 Query: 469 IDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFF 501 +D+G+ +MHSIR GS D+ VK F+ Sbjct: 393 VDIGLPTFAMHSIRELAGSHDLAHLVKVLGAFY 425 >2GLJ-A nrPDB Length = 461 Score = 440 bits (1131), Expect = e-124, Method: Composition-based stats. Identities = 104/482 (21%), Positives = 191/482 (39%), Gaps = 41/482 (8%) Query: 36 KENENSWCILEH----NYEDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNW 91 KE +N+W + + F +FI T V+ + +K ++ + + Sbjct: 3 KEYKNAWDKYDDKQLKEVFALGDRFKNFISNCKTERECVTELIKTAEKSGYRNIEDILAK 62 Query: 92 QDSIGEDGGKFYTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEG 151 +++ E G K Y G L F++GK G ++G+H+D+ + LK + Sbjct: 63 GETLKE-GDKVYANNRGKGLIMFLIGKE-PLYTGFKILGAHIDSPRLDLKQNPLYEDT-D 119 Query: 152 YGRIAVAPYGGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHF 211 + YGG W+ L I G ++ KK GT + + + PV + + H Sbjct: 120 LAMLETHYYGGIKKYQWVTLPLAIHG-VIVKKDGTI-VNVCVGEDDNDPVFGVSDILVHL 177 Query: 212 G-----KPAEGPFDKEDQTIPVIGFPTPDEEGNEPPTDDEKKSPLFGKHCIHLLRYVAKL 266 K A + ED I + G+ P D E+K K ++++ + + Sbjct: 178 ASEQLEKKASKVIEGEDLNILI---------GSIPLKDGEEKQ----KVKHNIMKILNEK 224 Query: 267 AGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEE 326 + + + +L++ K G + + DDR+C++ + A++ + Sbjct: 225 YDISEEDFVSAELEIVPAGKARDYGFDRSMVMGYGQDDRICAYTSFEAML------EMKN 278 Query: 327 SDLFSTVTLYDNEEIGSLTRQGAKGGLLESVV-ERSSSAFTKKPVDLHTVWANSIILSAD 385 + L D EE+GS+ G + E+ V + S + L NS +LS+D Sbjct: 279 AKKTCITILVDKEEVGSIGATGMQSKFFENTVADIMSLCGDYDELKLRKALYNSEMLSSD 338 Query: 386 VNHLYNPNFPEVYLKNHFPVPNVGITLS--LDPNGHMATDVVGTALVEELARRNGDKVQY 443 V+ ++PN+P V K + GI + G + + EL R + Sbjct: 339 VSAAFDPNYPNVMEKRNSAYLGKGIVFNKYTGSRGKSGCNDANPEYIAELRRILSKESVN 398 Query: 444 FQI----KNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNG 499 +Q K + GGTI LA + G + ID G+A L+MH+ + D+ ++ Sbjct: 399 WQTAELGKVDQGGGGTIAYILA-EYGMQVIDCGVALLNMHAPWEISSKADIYETKNGYSA 457 Query: 500 FF 501 F Sbjct: 458 FL 459 >2GLF-A nrPDB Length = 450 Score = 439 bits (1130), Expect = e-124, Method: Composition-based stats. Identities = 112/482 (23%), Positives = 201/482 (41%), Gaps = 48/482 (9%) Query: 35 KKENENSWCILE-HNYEDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQD 93 K E +N W + E ++E+++F+ K T V +LD+ F L D Sbjct: 1 KMERKNVWHHRKKEEIEAFSKEYMEFMSKAKTERMTVKEIKRILDESGFVPLE------D 54 Query: 94 SIGEDGG-KFYTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGY 152 G+ Y + G ++AF + + + +G+ ++ +H+D+ + KP + E Sbjct: 55 FAGDPMNMTVYAVNRGKAIAAFRVVDDLK--RGLNLVVAHIDSPRLDFKPNPLIED-EQI 111 Query: 153 GRIAVAPYGGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFG 212 YGG WL L I G +L+K GT EI+ + D PV IP L PH Sbjct: 112 ALFKTHYYGGIKKYHWLSIPLEIHG-VLFKNDGT-EIEIHIGDKPEDPVFTIPDLLPHL- 168 Query: 213 KPAEGPFDKEDQTIP--VIGFPTPDEEGNEPPTDDEKKSPLFGKHCIHLLRYVAKLAGVE 270 DKED I G G P + +EK++ ++L+ + ++ G+ Sbjct: 169 -------DKEDAKISEKFKGENLMLIAGTIPLSGEEKEAV-----KTNVLKILNEMYGIT 216 Query: 271 VSELIQMDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDLF 330 + + ++++ G+ + + A DDR+C++ A+ AL+ + Sbjct: 217 EEDFVSGEIEVVPAFSPREVGMDRSLIGAYGQDDRICAYTALRALLS-------ANPEKS 269 Query: 331 STVTLYDNEEIGSLTRQGAKGGL----LESVVERSSSAFTKKPVDLHTVWANSIILSADV 386 V +D EEIGS GAK L +++ + ++ +D V N+ ++S DV Sbjct: 270 IGVIFFDKEEIGSDGNTGAKARFYLKALRQILKMQGAKDSEFVLD--EVLENTSVISGDV 327 Query: 387 NHLYNPNFPEVYLKNHFPVPNVGITLS--LDPNGHMATDVVGTALVEELARRNGDKVQYF 444 NP + +V+ ++ P G+ L G +T+ V + + ++ + Sbjct: 328 CAAVNPPYKDVHDLHNAPKLGYGVALVKYTGARGKYSTNDAHAEFVARVRKVLNEQGVIW 387 Query: 445 QI----KNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGF 500 Q+ K + GGTI A + G+ ID+G A L MHS + D+ + Sbjct: 388 QVATLGKVDQGGGGTIAKFFAER-GSDVIDMGPALLGMHSPFEISSKADLFETYVAYRSL 446 Query: 501 FK 502 + Sbjct: 447 ME 448 >1Y7E-A nrPDB Length = 458 Score = 434 bits (1117), Expect = e-122, Method: Composition-based stats. Identities = 117/488 (23%), Positives = 187/488 (38%), Gaps = 50/488 (10%) Query: 36 KENENSWCILEHNYED----IAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNW 91 + +N W L ++ ++ + FI K T V ++ + K F EK N Sbjct: 1 MKKQNPWIYLNEEEKNQILNFSESYKKFISKFKTEREVTAYALDKAKKLGFINAEEKKNL 60 Query: 92 QDSIGEDGGKFYTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEG 151 G K + +++ I+GKN E G+ I SH D+ + KP + E Sbjct: 61 M-----PGDKIFYTCREKSVAFAIIGKN-PIEDGMNFIVSHTDSPRLDAKPSPISEENE- 113 Query: 152 YGRIAVAPYGGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHF 211 I YGG WL L I G + K EI + D+ PV IP + PH Sbjct: 114 LTFIKTNYYGGIKKYQWLSTPLSIRGVVFLKNGEKVEIN--IGDNENDPVFVIPDILPHL 171 Query: 212 ------GKPAEGPFDKEDQTIPVIGFPTPDEEGNEPPTDDEKKSPLFGKHCIHLLRYVAK 265 K ++ + E+ I + P +E N K + L+ + + Sbjct: 172 DRKIQRNKKSDEIVEGENLKILIGSLPIETKEKN--------------KVKLATLQLIKE 217 Query: 266 LAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTE 325 +E + + ++++ G K + A DD++C F ++ ++ + N Sbjct: 218 KYKIEEEDFVSSEIEIVPAGTAKDVGFDKALIGAYGQDDKICVFTSLESIFDLEETPNKT 277 Query: 326 ESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVERSSSAFTKKPVD---LHTVWANSIIL 382 + L D EEIGS G LE V K + + NS + Sbjct: 278 -----AICFLVDKEEIGSTGSTGLDSRYLEYFVSDMIFKIKKSEYNNLHVQKALWNSKSI 332 Query: 383 SADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGH----MATDVVGT--ALVEELARR 436 SADV NP F V+ + + P GI + + GH MA+D + + +L + Sbjct: 333 SADVCAAINPLFSSVHDEQNAPQLGYGIPI-MKYTGHGGKSMASDADAELVSYIRQLLNK 391 Query: 437 NGDKVQYFQI-KNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVK 495 N Q + K GGT+ LA G RTID+G A +SMHS T D+ Sbjct: 392 NNIAWQVATLGKVEEGGGGTVAKFLAG-YGIRTIDMGPAVISMHSPMEITSKFDLYNAYL 450 Query: 496 FFNGFFKH 503 + F++ Sbjct: 451 AYKAFYRE 458 >4EME-A nrPDB Length = 571 Score = 272 bits (696), Expect = 2e-73, Method: Composition-based stats. Identities = 78/315 (24%), Positives = 136/315 (43%), Gaps = 38/315 (12%) Query: 231 FPTPDEEGNEPPTDDEKKSPLFGKHCIH----LLRYVAKLAGVEVSELIQMDLDLFDVQK 286 +EE N+ D+ + LL ++K + +++ +L L D Q+ Sbjct: 249 TNQQNEEKNKHTKDNPNSKDIVEHINTDNSYPLLYLLSKELNCKEEDILDFELCLMDTQE 308 Query: 287 GTIGGIGKHFLFAPRLDDRL---CSFAAMIALICYAKDVNTEESDLFS------------ 331 G+ + F+ R D+ L C F I L+ K+ + E+ + Sbjct: 309 PCFTGVYEEFIEGARFDNLLGSFCVFEGFIELVNSIKNHTSNENTNHTNNITNDINDNIH 368 Query: 332 ----TVTLYDNEEIGSLTRQGAKGGLLESVVERSSSAFTKKP-----VDLHTVWAN---- 378 YD+EEIGSL+ GA+ ++ ++R S+ KK + + ++ N Sbjct: 369 NNLYISIGYDHEEIGSLSEVGARSYCTKNFIDRIISSVFKKEIHEKNLSVQEIYGNLVNR 428 Query: 379 SIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHMATDVVGTALVEEL----- 433 S IL+ D+ H +PN+PE NH + GI + + N + T + +L++ Sbjct: 429 SFILNVDMAHCSHPNYPETVQDNHQLFFHEGIAIKYNTNKNYVTSPLHASLIKRTFELYY 488 Query: 434 -ARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGL 492 + K Q F +KN++ G T+G +A+ ID+GI QL+MHSIR DV Sbjct: 489 NKYKQQIKYQNFMVKNDTPCGSTVGSMVAANLSMPGIDIGIPQLAMHSIREIAAVHDVFF 548 Query: 493 GVKFFNGFFKHWRSV 507 +K F+ ++ V Sbjct: 549 LIKGVFAFYTYYNQV 563 Score = 185 bits (470), Expect = 3e-47, Method: Composition-based stats. Identities = 50/195 (25%), Positives = 89/195 (45%), Gaps = 12/195 (6%) Query: 44 ILEHNYEDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFY 103 ++ + AQ+ + FI ++ + + E L+ + F LSE W ++ ++ G + Sbjct: 1 YVDKKAREYAQDALKFIQRSGSNFLACKNLKERLENNGFINLSEGETW--NLNKNEG-YV 57 Query: 104 TIRNGTNLSAFILGKNWRAEKGVGVIG-SHVDALTVKLKPVSFKDTAEGYGRIAVAPYGG 162 + N+ F +GKN+ + G +I H+D+ +K+ P + + +I V YG Sbjct: 58 LCKENRNICGFFVGKNFNIDTGSILISIGHIDSCALKISPNN-NVIKKKIHQINVECYGS 116 Query: 163 TLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPF--- 219 L W DR LG+ G++LYKK N++ L+ V +PSLA H F Sbjct: 117 GLWHTWFDRSLGLSGQVLYKK--GNKLVEKLIQINK-SVLFLPSLAIHLQNRTRYDFSVK 173 Query: 220 -DKEDQTIPVIGFPT 233 + E+ P+I Sbjct: 174 INYENHIKPIISTTL 188 >4X8I-A nrPDB Length = 346 Score = 61.0 bits (146), Expect = 1e-09, Method: Composition-based stats. Identities = 48/271 (17%), Positives = 88/271 (32%), Gaps = 39/271 (14%) Query: 238 GNEPPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFL 297 G PP + GK + + E +E + + + +H Sbjct: 112 GVLPPHLRREAKDQGGKIDWDSIIVDVGASSREEAEEMGFRIGTIGEFAPNFTRLSEHRF 171 Query: 298 FAPRLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESV 357 P LDDR+C + A+I A+ + E+D++ ++ EEIG + A Sbjct: 172 ATPYLDDRICLY----AMIEAARQLGEHEADIYIVASV--QEEIGLRGARVA-------- 217 Query: 358 VERSSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPN 417 S A + ++ DV PN P G + + PN Sbjct: 218 ----SFAIDPEVG-----------IAMDVTFAKQPNDKGKI----VPELGKGPVMDVGPN 258 Query: 418 GHMATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLS 477 + +E+A++ +Q + +G ++ G T L I Sbjct: 259 ----INPKLRQFADEVAKKYEIPLQ--VEPSPRPTGTDANVMQINREGVATAVLSIPIRY 312 Query: 478 MHSIRAATGSKDVGLGVKFFNGFFKHWRSVY 508 MHS ++DV +K + + + Sbjct: 313 MHSQVELADARDVDNTIKLAKALLEELKPMD 343 >2WZN-A nrPDB Length = 354 Score = 60.2 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 42/239 (17%), Positives = 80/239 (33%), Gaps = 39/239 (16%) Query: 270 EVSELIQMDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDL 329 E +E + + + +H P LDDR+C + A+I A+ + E+D+ Sbjct: 152 EEAEEMGFRVGTVGEFAPNFTRLNEHRFATPYLDDRICLY----AMIEAARQLGDHEADI 207 Query: 330 FSTVTLYDNEEIGSLTRQGAKGGLLESVVERSSSAFTKKPVDLHTVWANSIILSADVNHL 389 + ++ EE+G + A + V F K+P D + Sbjct: 208 YIVGSV--QEEVGLRGARVASYAINPEVGIAMDVTFAKQPHDKGKIV------------- 252 Query: 390 YNPNFPEVYLKNHFPVPNVGITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNN 449 P G + + PN + A +E+A++ +Q + Sbjct: 253 --------------PELGKGPVMDVGPN----INPKLRAFADEVAKKYEIPLQ--VEPSP 292 Query: 450 SRSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFFKHWRSVY 508 +G ++ G T L I MHS ++DV +K + + + Sbjct: 293 RPTGTDANVMQINKEGVATAVLSIPIRYMHSQVELADARDVDNTIKLAKALLEELKPMD 351 >4WWV-A nrPDB Length = 394 Score = 45.5 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 58/398 (14%), Positives = 116/398 (29%), Gaps = 99/398 (24%) Query: 110 NLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWL 169 N+ + G G +I +H+D + + F E G + V P GG L Sbjct: 77 NVVGYRKGSK---GSGKIMIAAHMDEIGL------FISHIEDDGFLRVIPIGGVL----- 122 Query: 170 DRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVI 229 +R L + R++ + + + + PH KP +E Q +P + Sbjct: 123 ERTL-LYQRVVVRTRDGRLYRGVIGLKP-----------PHVIKP------EEAQKVPEL 164 Query: 230 GFPTPDEEGNEPPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTI 289 D + + G+ V ++ D ++ Sbjct: 165 RELFIDVGASSKEE--------------------VEKMGIRVGDIAVFDREVA------E 198 Query: 290 GGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGA 349 G + + + DDR+ + AL E+ D+ + EE+G Sbjct: 199 LGWNR--ITSKAFDDRVGVVVMLKAL------EMLEKHDVDVYLVATVQEEVG------- 243 Query: 350 KGGLLESVVERSSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVG 409 + + + A + +++DV P V F G Sbjct: 244 ----------LKGAKTSAYGISPDVALAIDVTIASDV--------PGVAKSEWFTRLGYG 285 Query: 410 ITLSLDPNGHMATDVVGT---ALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLA-SQTG 465 + + + + + +A + Q I G T ++A ++ G Sbjct: 286 PAIKIVDGRNAGGLIAHPKVGEFLVSIAEKKRIPYQLDVIS----GGTTDASTIALNKEG 341 Query: 466 ARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFFKH 503 + I +HS +D+ F + Sbjct: 342 VAAGTISIPSRYIHSPVEVVDLRDLYNASLLAKAFIEE 379 >1VHO-A nrPDB Length = 346 Score = 44.0 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 21/113 (18%), Positives = 37/113 (32%), Gaps = 12/113 (10%) Query: 385 DVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHMATDVVGTALVEELARRNGDKVQYF 444 DV P F + PV +G + + + E+A+++ +Q Sbjct: 227 DVTFASEPPFSDHIELGKGPVIGLGPVVDRNLVQK----------IIEIAKKHNVSLQEE 276 Query: 445 QIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFF 497 + RSG + G RT + I MH+ +DV + Sbjct: 277 AV--GGRSGTETDFVQLVRNGVRTSLISIPLKYMHTPVEMVDPRDVEELARLL 327 >1Y0Y-A nrPDB Length = 353 Score = 42.1 bits (97), Expect = 7e-04, Method: Composition-based stats. Identities = 50/258 (19%), Positives = 93/258 (36%), Gaps = 48/258 (18%) Query: 244 DDEKKSPLFGKHCIHL---LRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAP 300 +D KK+P + + I + + A+ GV++ +I D G + +GKH + Sbjct: 128 EDRKKAPDWDQIFIDIGAESKEEAEDMGVKIGTVITWD--------GRLERLGKHRFVSI 179 Query: 301 RLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVER 360 DDR+ + ++ AK + ++D++ T+ EE+G Sbjct: 180 AFDDRIAVYT----ILEVAKQLKDAKADVYFVATV--QEEVGLRGA-------------- 219 Query: 361 SSSAFTKKPVDLHTVWANSIILSADVNHLYN-PNFPEVYLKNHFPVPNVGITLSLDPNGH 419 +SAF +P + DV + P PE H G + + Sbjct: 220 RTSAFGIEP---------DYGFAIDVTIAADIPGTPEHKQVTH---LGKGTAIKIMDRS- 266 Query: 420 MATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMH 479 + +EELA+++ Q ++ G G ++ G T L + +H Sbjct: 267 VICHPTIVRWLEELAKKHEIPYQ---LEILLGGGTDAGAIHLTKAGVPTGALSVPARYIH 323 Query: 480 SIRAATGSKDVGLGVKFF 497 S +DV V+ Sbjct: 324 SNTEVVDERDVDATVELM 341 >5DS0-A nrPDB Length = 359 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 36/200 (18%), Positives = 59/200 (29%), Gaps = 31/200 (15%) Query: 298 FAPRLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESV 357 DDR+ +F M A I KD E + EE+G Q Sbjct: 175 MGKAFDDRIGAFVLMEA-IRRMKDQGIEHPNTVYGSATV-QEEVGLRGAQ---------- 222 Query: 358 VERSSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPN 417 T VD + ++ DV P + G L + Sbjct: 223 -------TTAHVVDPDVALVLEVDIAGDV--------PGIKPHEALTKMGKGPGLVT-YD 266 Query: 418 GHMATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLS 477 M + V +A++ +Q Q+ S G G ++ G ++ + I Sbjct: 267 RSMIPNQPLKEFVINVAKQAQIPLQLSQM---SGGGTDAGRIHMNRAGCPSVVITIPTRH 323 Query: 478 MHSIRAATGSKDVGLGVKFF 497 +HS KD ++ Sbjct: 324 IHSHVGLLSLKDTENAIRLV 343 >1VHE-A nrPDB Length = 373 Score = 37.1 bits (84), Expect = 0.018, Method: Composition-based stats. Identities = 41/269 (15%), Positives = 78/269 (28%), Gaps = 41/269 (15%) Query: 233 TPDEEGNEPPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDL----DLFDVQKGT 288 G++PP SP K + + + E ++ + + + T Sbjct: 114 ITGVIGSKPP---HILSPEARKKSVEIKDMFIDIGASSREEALEWGVLPGDMIVPHFEFT 170 Query: 289 IGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQG 348 + + FL A D+R+ A+ L NT+ ++ V EE+G Sbjct: 171 VMN-NEKFLLAKAWDNRIGCAIAIDVLRNLQ---NTDHPNIVYGVGTV-QEEVG------ 219 Query: 349 AKGGLLESVVERSSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNV 408 + + + + ++ D P + K Sbjct: 220 -----------LRGAKTAAHTIQPDIAFGVDVGIAGDT--------PGISEKEAQSKMGK 260 Query: 409 GITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGART 468 G + + + M + V A G Q+ I + G G + G Sbjct: 261 GPQIIV-YDASMVSHKGLRDAVVATAEEAGIPYQFDAI---AGGGTDSGAIHLTANGVPA 316 Query: 469 IDLGIAQLSMHSIRAATGSKDVGLGVKFF 497 + + IA +H+ A D VK Sbjct: 317 LSITIATRYIHTHAAMLHRDDYENAVKLI 345 >5NE9-A nrPDB Length = 331 Score = 35.5 bits (80), Expect = 0.061, Method: Composition-based stats. Identities = 18/122 (14%), Positives = 39/122 (31%), Gaps = 7/122 (5%) Query: 376 WANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHMATDVVGTALVEELAR 435 ++ DV + +K H + G L + +++ + L+ E+A Sbjct: 211 VPADEAIAIDVTDSADTP---KAIKRHAMRLSGGPALKVKDRASISSKRILENLI-EIAE 266 Query: 436 RNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVK 495 + K Q ++ + G ++ G + + I + S DV V Sbjct: 267 KFDIKYQ---MEVLTFGGTNAMGYQRTREGIPSATVSIPTRYVASPSEMIAPDDVEATVD 323 Query: 496 FF 497 Sbjct: 324 LL 325 >2EC6-A nrPDB Length = 838 Score = 32.4 bits (72), Expect = 0.53, Method: Composition-based stats. Identities = 22/154 (14%), Positives = 44/154 (28%), Gaps = 15/154 (9%) Query: 132 HVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLLYKKKGTNEIKS 191 H+ + KP +G+ + Y G + I G L K NE Sbjct: 557 HIGKNRMFTKPGKPTRPNQGHAHFELHHYAG-------NVPYSIAGWLDKNKDPINENVV 609 Query: 192 ALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPDEEGNEPPTDDEKKSPL 251 +L+ + P L + + P + ++ L Sbjct: 610 SLLAVSKEP------LVAELFRAPDEPAGGAGGKKKKKSSAFQTISAVHRESLNKLMKNL 663 Query: 252 FGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQ 285 + H + + ++ L+ +L L +Q Sbjct: 664 YSTHPHFVRCIIPNE--LKQPGLVDAELVLHQLQ 695 >1ZMR-A nrPDB Length = 387 Score = 31.7 bits (70), Expect = 0.87, Method: Composition-based stats. Identities = 20/116 (17%), Positives = 39/116 (33%), Gaps = 13/116 (11%) Query: 171 RDLGIGG-RLLYKKKGTNEIKSALVDSTPLPVCRIPSLAP------------HFGKPAEG 217 DL + G R+ + +K V S +P++ H G+P EG Sbjct: 7 TDLDLAGKRVFIRADLNVPVKDGKVTSDARIRASLPTIELALKQGAKVMVTSHLGRPTEG 66 Query: 218 PFDKEDQTIPVIGFPTPDEEGNEPPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSE 273 +++E +PV+ + D + + +L V G + + Sbjct: 67 EYNEEFSLLPVVNYLKDKLSNPVRLVKDYLDGVDVAEGELVVLENVRFNKGEKKDD 122 >5UM0-A nrPDB Length = 235 Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 13/87 (14%), Positives = 29/87 (33%), Gaps = 6/87 (6%) Query: 210 HFGKPAEGPFDKEDQTIPVIGFPTPDEEGNEPPTDDEKKSPLFGKHCIHLLRYVAKLAGV 269 H PA+ D E+ + + P E P K L H L + G+ Sbjct: 147 HL--PADVVPDGENLKV-TLERVLPFWEDQIAPAILSGKRVLVAAHGNSLRALAKHIEGI 203 Query: 270 EVSELIQMDLDLFDVQKGTIGGIGKHF 296 +++ +++ + + + + Sbjct: 204 SDEDIMGLEI---PTGQPLVYKLDDNL 227 >4NG4-A nrPDB Length = 404 Score = 30.1 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 31/80 (38%), Gaps = 12/80 (15%) Query: 178 RLLYKKKGTNEIKSALVDSTPLPVCRIPSL------------APHFGKPAEGPFDKEDQT 225 R++ ++ +K+ + + V +P++ H G+P EG F+KE Sbjct: 26 RVMIREDLNVPMKNGKITNDERIVRALPTIQKAIEQKARVMILSHLGRPEEGKFEKEFSL 85 Query: 226 IPVIGFPTPDEEGNEPPTDD 245 PV + P +D Sbjct: 86 APVARLLSKKLNQKVPLIND 105 >1ZOF-A nrPDB Length = 198 Score = 30.1 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 28/151 (18%), Positives = 48/151 (31%), Gaps = 15/151 (9%) Query: 81 NFKYLSEKSNWQDSIGEDG------GKFYTIRNGTNLSAFILGKNWRAEKGVGVIGSHVD 134 + E ++G++G K +T T + AF EKG VIG +D Sbjct: 17 GNNEVDEHFELSKNLGKNGVILFFWPKDFTFVCPTEIIAFDKRVKDFHEKGFNVIGVSID 76 Query: 135 ALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRD------LGIGGRLLYKKKGTNE 188 + V + G G+++ + D D + + G L K Sbjct: 77 SEQVHFAWKNTPVEKGGIGQVSFPMVADITKSISRDYDVLFEEAIALRGAFLIDKNMKVR 136 Query: 189 ---IKSALVDSTPLPVCRIPSLAPHFGKPAE 216 I + + R+ HF + E Sbjct: 137 HAVINDLPLGRNADEMLRMVDALLHFEEHGE 167 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.124 0.301 Lambda K H 0.267 0.0376 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,621,192 Number of Sequences: 36641 Number of extensions: 691444 Number of successful extensions: 2176 Number of sequences better than 10.0: 23 Number of HSP's better than 10.0 without gapping: 21 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 2049 Number of HSP's gapped (non-prelim): 50 length of query: 514 length of database: 10,336,785 effective HSP length: 101 effective length of query: 413 effective length of database: 6,636,044 effective search space: 2740686172 effective search space used: 2740686172 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 61 (28.2 bits)