BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P14740 (767 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2GBG-A nrPDB 1535 0.0 2QT9-A nrPDB 1362 0.0 2AJB-A nrPDB 1267 0.0 1Z68-A nrPDB 838 0.0 4WJL-A nrPDB 489 e-138 1XFD-A nrPDB 443 e-124 5OLJ-A nrPDB 310 1e-84 2ECF-A nrPDB 198 6e-51 5YP1-A nrPDB 190 2e-48 6EOT-A nrPDB 166 5e-41 2EEP-A nrPDB 159 4e-39 4Q1V-A nrPDB 155 6e-38 6EOR-A nrPDB 150 2e-36 4HXF-B nrPDB 65 9e-11 5L8S-A nrPDB 63 5e-10 3O4I-A nrPDB 49 7e-06 3AZQ-A nrPDB 49 9e-06 5UW6-A nrPDB 43 4e-04 6IGR-A nrPDB 41 0.002 3DYV-A nrPDB 36 0.059 2D81-A nrPDB 34 0.22 3KSR-A nrPDB 33 0.36 2BKL-A nrPDB 31 1.7 1NW1-A nrPDB 30 3.9 1LTX-R nrPDB 30 3.9 3TM5-A nrPDB 30 4.1 5T88-A nrPDB 30 4.4 4GGR-A nrPDB 30 5.8 6HIS-A nrPDB 29 6.0 4YB9-D nrPDB 29 7.2 3IVU-A nrPDB 29 7.5 4GAA-A nrPDB 29 8.0 >2GBG-A nrPDB Length = 730 Score = 1535 bits (3973), Expect = 0.0, Method: Compositional matrix adjust. Identities = 730/730 (100%), Positives = 730/730 (100%) Query: 38 RRTYTLADYLKNTFRVKSYSLRWVSDSEYLYKQENNILLFNAEHGNSSIFLENSTFEIFG 97 RRTYTLADYLKNTFRVKSYSLRWVSDSEYLYKQENNILLFNAEHGNSSIFLENSTFEIFG Sbjct: 1 RRTYTLADYLKNTFRVKSYSLRWVSDSEYLYKQENNILLFNAEHGNSSIFLENSTFEIFG 60 Query: 98 DSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQ 157 DSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQ Sbjct: 61 DSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQ 120 Query: 158 EGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSALWWSPN 217 EGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSALWWSPN Sbjct: 121 EGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSALWWSPN 180 Query: 218 GTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSST 277 GTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSST Sbjct: 181 GTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSST 240 Query: 278 TTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTTLVWNC 337 TTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTTLVWNC Sbjct: 241 TTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTTLVWNC 300 Query: 338 PTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVCTF 397 PTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVCTF Sbjct: 301 PTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVCTF 360 Query: 398 ITKGAWEVISIEALTSDYLYYISNEYKEMPGGRNLYKIQLTDHTNKKCLSCDLNPERCQY 457 ITKGAWEVISIEALTSDYLYYISNEYKEMPGGRNLYKIQLTDHTNKKCLSCDLNPERCQY Sbjct: 361 ITKGAWEVISIEALTSDYLYYISNEYKEMPGGRNLYKIQLTDHTNKKCLSCDLNPERCQY 420 Query: 458 YSVSLSKEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDF 517 YSVSLSKEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDF Sbjct: 421 YSVSLSKEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDF 480 Query: 518 IVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVA 577 IVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVA Sbjct: 481 IVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVA 540 Query: 578 SFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVT 637 SFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVT Sbjct: 541 SFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVT 600 Query: 638 SMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFK 697 SMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFK Sbjct: 601 SMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFK 660 Query: 698 QVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMS 757 QVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMS Sbjct: 661 QVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMS 720 Query: 758 HFLQQCFSLR 767 HFLQQCFSLR Sbjct: 721 HFLQQCFSLR 730 >2QT9-A nrPDB Length = 766 Score = 1362 bits (3524), Expect = 0.0, Method: Compositional matrix adjust. Identities = 650/768 (84%), Positives = 705/768 (91%), Gaps = 5/768 (0%) Query: 1 MKTPWKVLLGLLGVAALVTIITVPVVLLNK--DEAAADSRRTYTLADYLKNTFRVKSYSL 58 MKTPWKVLLGLLG AALVTIITVPVVLLNK D+A AD+R+TYTL DYLKNT+R+K YSL Sbjct: 1 MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADTRKTYTLTDYLKNTYRLKLYSL 60 Query: 59 RWVSDSEYLYKQENNILLFNAEHGNSSIFLENSTFEIFGDSISDYSVSPDRLFVLLEYNY 118 RW+SD EYLYKQENNIL+FNAE+GNSS+FLENSTF+ FG SI+DYS+SPD F+LLEYNY Sbjct: 61 RWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNY 120 Query: 119 VKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQEGHKLAYVWKNDIYVKIEPHL 178 VKQWRHSYTASY IYDLNKRQLITEE+IPNNTQW+TWS GHKLAYVW NDIYVKIEP+L Sbjct: 121 VKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNL 180 Query: 179 PSHRITSTGKENVIFNGINDWVYEEEIFGAYSALWWSPNGTFLAYAQFNDTGVPLIEYSF 238 PS+RIT TGKE++I+NGI DWVYEEE+F AYSALWWSPNGTFLAYAQFNDT VPLIEYSF Sbjct: 181 PSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSF 240 Query: 239 YSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSSTTTTIPMQITAPASVTTGDHYL 298 YSDESLQYPKTV +PYPKAGAVNPTVKFF+VNTDSLSS T +QITAPAS+ GDHYL Sbjct: 241 YSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYL 300 Query: 299 CDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTTLVWNCPTTQEHIETSATGWCGRFRPA 358 CDV W +++RISLQWLRRIQNYSVM ICDYD+++ WNC ++HIE S TGW GRFRP+ Sbjct: 301 CDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPS 360 Query: 359 EPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVCTFITKGAWEVISIEALTSDYLYY 418 EPHFT DG+SFYKI+S+++GY+HIC FQ D+K CTFITKG WEVI IEALTSDYLYY Sbjct: 361 EPHFTLDGNSFYKIISNEEGYRHICYFQIDKKD---CTFITKGTWEVIGIEALTSDYLYY 417 Query: 419 ISNEYKEMPGGRNLYKIQLTDHTNKKCLSCDLNPERCQYYSVSLSKEAKYYQLGCRGPGL 478 ISNEYK MPGGRNLYKIQL+D+T CLSC+LNPERCQYYSVS SKEAKYYQL C GPGL Sbjct: 418 ISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGL 477 Query: 479 PLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDFIVLNETRFWYQMILPPHFDKS 538 PLYTLH S + K LRVLEDNSALDKMLQ+VQMPSKKLDFI+LNET+FWYQMILPPHFDKS Sbjct: 478 PLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKS 537 Query: 539 KKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKR 598 KKYPLL+DVYAGPCSQKAD FRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAIN+R Sbjct: 538 KKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRR 597 Query: 599 LGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVS 658 LGT EVEDQIEAARQF KMGFVD+KR+AIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVS Sbjct: 598 LGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVS 657 Query: 659 RWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSA 718 RWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSA Sbjct: 658 RWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSA 717 Query: 719 QISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFLQQCFSL 766 QISKALVD GVDFQAMWYTDEDHGIASSTAHQHIY+HMSHF++QCFSL Sbjct: 718 QISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSL 765 >2AJB-A nrPDB Length = 728 Score = 1267 bits (3278), Expect = 0.0, Method: Compositional matrix adjust. Identities = 598/730 (81%), Positives = 649/730 (88%), Gaps = 3/730 (0%) Query: 37 SRRTYTLADYLKNTFRVKSYSLRWVSDSEYLYKQENNILLFNAEHGNSSIFLENSTFEIF 96 SRRTYTL DYLK+TFRVK Y+L+W+SD EYLYKQENNILLFNAE+GNSSIFLENSTF+ Sbjct: 1 SRRTYTLTDYLKSTFRVKFYTLQWISDHEYLYKQENNILLFNAEYGNSSIFLENSTFDEL 60 Query: 97 GDSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWS 156 G S +DYSVSPDR F+L EYNYVKQWRHSYTASY IYDLNKRQLITEE+IPNNTQWITWS Sbjct: 61 GYSTNDYSVSPDRQFILFEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWITWS 120 Query: 157 QEGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSALWWSP 216 GHKLAYVW NDIYVK EP+L S RIT TGKENVI+NG+ DWVYEEE+F AYSALWWSP Sbjct: 121 PVGHKLAYVWNNDIYVKNEPNLSSQRITWTGKENVIYNGVTDWVYEEEVFSAYSALWWSP 180 Query: 217 NGTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSS 276 NGTFLAYAQFNDT VPLIEYSFYSDESLQYPKTV IPYPKAGA NPTVKFF+V+T +LS Sbjct: 181 NGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRIPYPKAGAENPTVKFFVVDTRTLSP 240 Query: 277 TTTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTTLVWN 336 + QI PASV GDHYLC V WV+E+RISLQW+RR QNYS++ ICDYD++T W Sbjct: 241 NASVTSYQIVPPASVLIGDHYLCGVTWVTEERISLQWIRRAQNYSIIDICDYDESTGRWI 300 Query: 337 CPTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVCT 396 ++HIE S TGW GRFRPAEPHFTSDG+SFYKI+S+++GYKHIC FQ D+ CT Sbjct: 301 SSVARQHIEISTTGWVGRFRPAEPHFTSDGNSFYKIISNEEGYKHICHFQTDKSN---CT 357 Query: 397 FITKGAWEVISIEALTSDYLYYISNEYKEMPGGRNLYKIQLTDHTNKKCLSCDLNPERCQ 456 FITKGAWEVI IEALTSDYLYYISNE+K MPGGRNLY+IQL D+T CLSC+LNPERCQ Sbjct: 358 FITKGAWEVIGIEALTSDYLYYISNEHKGMPGGRNLYRIQLNDYTKVTCLSCELNPERCQ 417 Query: 457 YYSVSLSKEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLD 516 YYS S S +AKYYQL C GPGLPLYTLH S+ KELRVLEDNSALDKMLQDVQMPSKKLD Sbjct: 418 YYSASFSNKAKYYQLRCFGPGLPLYTLHSSSSDKELRVLEDNSALDKMLQDVQMPSKKLD 477 Query: 517 FIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIV 576 I L+ T+FWYQMILPPHFDKSKKYPLLI+VYAGPCSQK D FRL+WATYLASTENIIV Sbjct: 478 VINLHGTKFWYQMILPPHFDKSKKYPLLIEVYAGPCSQKVDTVFRLSWATYLASTENIIV 537 Query: 577 ASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYV 636 ASFDGRGSGYQGDKIMHAIN+RLGT EVEDQIEA RQF KMGFVD KR+AIWGWSYGGYV Sbjct: 538 ASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEATRQFSKMGFVDDKRIAIWGWSYGGYV 597 Query: 637 TSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENF 696 TSMVLG+GSGVFKCGIAVAPVS+WEYYDSVYTERYMGLPTPEDNLD+YRNSTVMSRAENF Sbjct: 598 TSMVLGAGSGVFKCGIAVAPVSKWEYYDSVYTERYMGLPTPEDNLDYYRNSTVMSRAENF 657 Query: 697 KQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHM 756 KQVEYLLIHGTADDNVHFQQSAQ+SKALVDAGVDFQ MWYTDEDHGIAS+ AHQHIY+HM Sbjct: 658 KQVEYLLIHGTADDNVHFQQSAQLSKALVDAGVDFQTMWYTDEDHGIASNMAHQHIYTHM 717 Query: 757 SHFLQQCFSL 766 SHFL+QCFSL Sbjct: 718 SHFLKQCFSL 727 >1Z68-A nrPDB Length = 719 Score = 838 bits (2164), Expect = 0.0, Method: Compositional matrix adjust. Identities = 394/729 (54%), Positives = 529/729 (72%), Gaps = 13/729 (1%) Query: 39 RTYTLADYLKNTFRVKSYSLRWVSDSEYLYKQ-ENNILLFNAEHGNSSIFLENSTFEIFG 97 R TL D L TF K++ W+S EYL++ +NNI+L+N E G S L N T + Sbjct: 2 RALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMK--S 59 Query: 98 DSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQ 157 + S+Y +SPDR FV LE +Y K WR+SYTA+Y IYDL+ + + ++P Q++ WS Sbjct: 60 VNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSP 119 Query: 158 EGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSALWWSPN 217 G KLAYV++N+IY+K P P +IT G+EN IFNGI DWVYEEE+ ALWWSPN Sbjct: 120 VGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPN 179 Query: 218 GTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSST 277 G FLAYA+FNDT +P+I YS+Y DE QYP+T+ IPYPKAGA NP V+ FI++T + Sbjct: 180 GKFLAYAEFNDTDIPVIAYSYYGDE--QYPRTINIPYPKAGAKNPVVRIFIIDT---TYP 234 Query: 278 TTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTTLVWNC 337 P ++ PA + + D+Y + WV+++R+ LQWL+R+QN SV++ICD+ + W+C Sbjct: 235 AYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDC 294 Query: 338 PTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVCTF 397 P TQEHIE S TGW G F + P F+ D S+YKI SDKDGYKHI + KD + Sbjct: 295 PKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHI-HYIKDTVENAIQ-- 351 Query: 398 ITKGAWEVISIEALTSDYLYYISNEYKEMPGGRNLYKIQLTDHT-NKKCLSCDLNPERCQ 456 IT G WE I+I +T D L+Y SNE++E PG RN+Y+I + + +KKC++C L ERCQ Sbjct: 352 ITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQ 411 Query: 457 YYSVSLSKEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLD 516 YY+ S S AKYY L C GPG+P+ TLH +E+++LE+N L+ L+++Q+P +++ Sbjct: 412 YYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIK 471 Query: 517 FIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIV 576 + ++E WY+MILPP FD+SKKYPLLI VY GPCSQ + F +NW +YLAS E +++ Sbjct: 472 KLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVI 531 Query: 577 ASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYV 636 A DGRG+ +QGDK+++A+ ++LG EVEDQI A R+F++MGF+D KR+AIWGWSYGGYV Sbjct: 532 ALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYV 591 Query: 637 TSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENF 696 +S+ L SG+G+FKCGIAVAPVS WEYY SVYTER+MGLPT +DNL+HY+NSTVM+RAE F Sbjct: 592 SSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYF 651 Query: 697 KQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHM 756 + V+YLLIHGTADDNVHFQ SAQI+KALV+A VDFQAMWY+D++HG+ S + H+Y+HM Sbjct: 652 RNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGL-SGLSTNHLYTHM 710 Query: 757 SHFLQQCFS 765 +HFL+QCFS Sbjct: 711 THFLKQCFS 719 >4WJL-A nrPDB Length = 719 Score = 489 bits (1258), Expect = e-138, Method: Compositional matrix adjust. Identities = 263/739 (35%), Positives = 426/739 (57%), Gaps = 33/739 (4%) Query: 37 SRRTYTLADYLKNTFRVKSYSLRWVSDSEYLYKQEN-NILLFNAEHGNSSIFLENSTFEI 95 S +L D + F + RW++D++ +YK EN +++ N E +++ LEN+TF Sbjct: 1 SETRLSLEDLFRKDFVLHDPEARWINDTDVVYKSENGHVIKLNIETNATTLLLENTTFVT 60 Query: 96 FGDSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQL--ITEEKIPNNT-QW 152 F S +SVSPD +VLL Y+ + + +SYTASY IY+++ R++ + ++ ++ Q+ Sbjct: 61 F--KASRHSVSPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTREVWELNPPEVEDSVLQY 118 Query: 153 ITWSQEGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSAL 212 W +G +L Y+++N+IY + + S R+TS+GKE +IFNGI DW+YEEE+ ++ A Sbjct: 119 AAWGVQGQQLIYIFENNIYYQPDIKSSSLRLTSSGKEEIIFNGIADWLYEEELLHSHIAH 178 Query: 213 WWSPNGTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTD 272 WWSP+G LA+ ND+ VP + ++ YPK PYPKAG +NPT+K ++VN Sbjct: 179 WWSPDGERLAFLMINDSLVPTMVIPRFT--GALYPKGKQYPYPKAGQMNPTIKLYVVNLY 236 Query: 273 SLSSTTTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTT 332 + T +P P S + ++Y+ V WVS + ++WL R QN S++ +C+ T Sbjct: 237 GPTHTLELMP-----PDSFKSREYYITMVKWVSNTKTVVRWLNRAQNISILTVCE----T 287 Query: 333 LVWNCPTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDG----YKHICQFQKD 388 C + E ++ W + + EP F+ DGS F+ V K G + HI F Sbjct: 288 TTGAC---SKKYEMTSDTWLSQ-QNEEPVFSRDGSKFFMTVPVKQGGRGEFHHIAMFLIQ 343 Query: 389 RKPEQVCT-FITKGAWEVISIEAL--TSDYLYYISNEYKEMPGGRNLYKIQLTDHTNKKC 445 K EQ+ +T G WEVI I A T+ +Y++S E P GR LY N++C Sbjct: 344 SKSEQITVRHLTSGNWEVIKILAYDETTQKIYFLSTE--SSPRGRQLYSASTEGLLNRQC 401 Query: 446 LSCDLNPERCQYYSVSLSKEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKML 505 +SC+ E+C Y+ S S +++ L C GP +P+ +LH + + + +LE NS L + + Sbjct: 402 ISCNFMKEQCTYFDASFSPMNQHFLLFCEGPRVPVVSLHSTDNPAKYFILESNSMLKEAI 461 Query: 506 QDVQMPSKKLDFIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWA 565 ++ ++ + +++ Q+ LP F +Y LL+ + P Q F ++W Sbjct: 462 LKKKIGKPEIKILHIDDYELPLQLSLPKDFMDRNQYALLLIMDEEPGGQLVTDKFHIDWD 521 Query: 566 TYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRV 625 + L +N+IVA FDGRGSG+QG KI+ I++RLG++EV+DQI A + LK+ ++DSKR+ Sbjct: 522 SVLIDMDNVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRL 581 Query: 626 AIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYR 685 +I+G YGGY+ SM+L S +FKCG VAP++ + Y S ++ERY+G+P+ E++ Y+ Sbjct: 582 SIFGKGYGGYIASMILKSDEKLFKCGSVVAPITDLKLYASAFSERYLGMPSKEEST--YQ 639 Query: 686 NSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIAS 745 ++V+ K+ L+IHGTAD VHFQ SA++ K L+ AGV++ Y DE H ++ Sbjct: 640 AASVLHNVHGLKEENILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGHNVSE 699 Query: 746 STAHQHIYSHMSHFLQQCF 764 + + H+YS + F C Sbjct: 700 KSKY-HLYSTILKFFSDCL 717 >1XFD-A nrPDB Length = 723 Score = 443 bits (1139), Expect = e-124, Method: Compositional matrix adjust. Identities = 249/747 (33%), Positives = 406/747 (54%), Gaps = 43/747 (5%) Query: 38 RRTYTLADYLKNTFRVKSYSLRWVSDSEYLYK-QENNILLFNAEHGNSSIFLENSTFEIF 96 ++ T+ D F++ +W+SD+E++Y+ Q+ + L+N E S++ +E E Sbjct: 2 KKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEGKKIESL 61 Query: 97 GDSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDL---NKRQLITEEKIPNNTQWI 153 Y +SPDR + L YN ++HSYT Y + + + + L E Q+ Sbjct: 62 --RAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAKLQYA 119 Query: 154 TWSQEGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSALW 213 W +G +L ++++N+IY + R+ STGKE VI+NG++DW+YEEEI + A W Sbjct: 120 GWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHIAHW 179 Query: 214 WSPNGTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDS 273 WSP+GT LAYA ND+ VP++E Y+ YP YPKAG+ NP++ ++ + Sbjct: 180 WSPDGTRLAYAAINDSRVPIMELPTYTGSI--YPTVKPYHYPKAGSENPSISLHVIGLNG 237 Query: 274 LSSTTTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTTL 333 T +++ P ++Y+ V W + ++++ WL R QN S++ +CD TT Sbjct: 238 -----PTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCD--ATTG 290 Query: 334 VWNCPTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDG----YKHIC--QFQK 387 V T++H E + W R + EP F+ DG F+ I + G + HI Q Sbjct: 291 V----CTKKH-EDESEAWLHR-QNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQP 344 Query: 388 DRKPEQVCTFITKGAWEVISIEAL--TSDYLYYISNEYKEMPGGRNLYKIQLTDHTNKKC 445 + + + + IT G W+V I A + +Y++S E ++P R LY + N++C Sbjct: 345 NSSNDNIQS-ITSGDWDVTKILAYDEKGNKIYFLSTE--DLPRRRQLYSANTVGNFNRQC 401 Query: 446 LSCDLNPERCQYYSVSLSKEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKML 505 LSCDL E C Y+S S S ++ L C GPG+P+ T+H +TD+K++ LE N + K + Sbjct: 402 LSCDL-VENCTYFSASFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAI 460 Query: 506 QDVQMPSKKLDFIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWA 565 D QMP + I +++ Q++ P F + YPLL+ V P SQ F ++W Sbjct: 461 NDRQMPKVEYRDIEIDDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWE 520 Query: 566 TYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRV 625 T + S+ +V DGRGSG+QG K++H + +RLG LE +DQ+EA R LK ++D RV Sbjct: 521 TVMVSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRV 580 Query: 626 AIWGWSYGGYVTSMVL---GSGSG-VFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNL 681 A++G YGGY+++ +L G G F CG A++P++ ++ Y S ++ERY+GL L Sbjct: 581 AVFGKDYGGYLSTYILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGL----HGL 636 Query: 682 DH--YRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDE 739 D+ Y + V R ++ ++L+IH TAD+ +HFQ +A++ L+ ++ Y DE Sbjct: 637 DNRAYEMTKVAHRVSALEEQQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDE 696 Query: 740 DHGIASSTAHQHIYSHMSHFLQQCFSL 766 H SS+ QH+Y + +F +CF + Sbjct: 697 SHYFTSSSLKQHLYRSIINFFVECFRI 723 >5OLJ-A nrPDB Length = 723 Score = 310 bits (795), Expect = 1e-84, Method: Compositional matrix adjust. Identities = 224/720 (31%), Positives = 347/720 (48%), Gaps = 50/720 (6%) Query: 52 RVKSYSLRWVSDSEY---LYKQENNILLFNAEHGNS--SIFLENSTFEIFGDSISDYSVS 106 R +R + D E+ + ++ I+ +N G + ++F E I +Y VS Sbjct: 39 RSAGRGIRSMPDGEHYTEMNRERTAIVRYNYASGKAVDTLFSIERARECPFKQIQNYEVS 98 Query: 107 PDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQEGHKLAYVW 166 +LL + +RHSY A+ YD+ + + + T+S +G +A+V Sbjct: 99 STGHHILLFTDMESIYRHSYRAAVYDYDVRRNLVKPLSEHVGKVMIPTFSPDGRMVAFVR 158 Query: 167 KNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSALWWSPNGTFLAYAQF 226 N+I++K ++T+ G+ N + NG DWVYEEE FG + + WS + FLA+ + Sbjct: 159 DNNIFIKKFDFDTEVQVTTDGQINSVLNGATDWVYEEE-FGVTNLMSWSADNAFLAFVRS 217 Query: 227 NDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSSTTTTIPMQIT 286 +++ VP Y D+ YP+ YPKAG N TV + N ++ + ++P+ Sbjct: 218 DESAVPEYRMPMYEDK--LYPEDYTYKYPKAGEKNSTVSLHLYNVADRNTKSVSLPID-- 273 Query: 287 APASVTTGDHYLCDVAWV-SEDRISLQWLRRIQNYSVMAICDYDKTTLVWNCPTTQEHIE 345 D Y+ +A+ + D +++ L R+QN M +LV + Sbjct: 274 -------ADGYIPRIAFTDNADELAVMTLNRLQNDFKMYYVH--PKSLVPKLILQDMNKR 324 Query: 346 TSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVCTFITKGAWEV 405 + W + FT+ G Y VS+KDG+ HI + + IT G W+V Sbjct: 325 YVDSDWIQALK-----FTAGGGFAY--VSEKDGFAHIYLYDNKGVMHRR---ITSGNWDV 374 Query: 406 ISIEAL-TSDYLYYISNEYKEMPGGRNLYKIQLTDHTNKKCLSCDLNPERCQYYSVSLSK 464 + + S ++Y S E E P R +Y I K L+ N S Sbjct: 375 TKLYGVDASGTVFYQSAE--ESPIRRAVYAIDAKGRKTKLSLNVGTN-------DALFSG 425 Query: 465 EAKYYQLGCRGPGLP-LYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDFIVLN-- 521 YY P + ++ RS KELR LEDN AL + L+ + K+ I Sbjct: 426 NYAYYINTYSSAATPTVVSVFRSKGAKELRTLEDNVALRERLKAYRYNPKEFTIIKTQSA 485 Query: 522 -ETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFD 580 E W ++ P FD S+ YP+L+ Y+GP SQ+ + +W YLAS + +VA D Sbjct: 486 LELNAW--IVKPIDFDPSRHYPVLMVQYSGPNSQQVLDRYSFDWEHYLAS-KGYVVACVD 542 Query: 581 GRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMV 640 GRG+G +G++ +LG E +DQI AA ++ +VD+ R+ IWGWSYGGY T M Sbjct: 543 GRGTGARGEEWRKCTYMQLGVFESDDQIAAATAIGQLPYVDAARIGIWGWSYGGYTTLMS 602 Query: 641 LGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVE 700 L G+G FK GIAVAPV+ W +YDSVYTER+M TP++N Y+ S+ + A Q Sbjct: 603 LCRGNGTFKAGIAVAPVADWRFYDSVYTERFM--RTPKENASGYKMSSALDVASQL-QGN 659 Query: 701 YLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFL 760 L++ G+ADDNVH Q + ++ALV A + F Y D++H I H+Y+ + FL Sbjct: 660 LLIVSGSADDNVHLQNTMLFTEALVQANIPFDMAIYMDKNHSIYGGNTRYHLYTRKAKFL 719 >2ECF-A nrPDB Length = 741 Score = 198 bits (504), Expect = 6e-51, Method: Compositional matrix adjust. Identities = 191/693 (27%), Positives = 294/693 (42%), Gaps = 90/693 (12%) Query: 99 SISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNK------RQLITEEKIPNNTQW 152 I DY SPD +L +YDL + RQL E + + Sbjct: 110 GIVDYQWSPDAQRLLFPLG----------GELYLYDLKQEGKAAVRQLTHGEGFATDAKL 159 Query: 153 ITWSQEGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSAL 212 S +G ++++ +++V ++T+ G I NGI ++V +EE+ ++ Sbjct: 160 ---SPKGGFVSFIRGRNLWVIDLASGRQMQLTADG-STTIGNGIAEFVADEEM-DRHTGY 214 Query: 213 WWSPNGTFLAYAQFNDTGVPLIE-YSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNT 271 WW+P+ + +AYA+ +++ VP+ + Y Y+D + + YP AG N VK +++ Sbjct: 215 WWAPDDSAIAYARIDESPVPVQKRYEVYADRT----DVIEQRYPAAGDANVQVKLGVIS- 269 Query: 272 DSLSSTTTTIPMQITAPASVTTG---DHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDY 328 P + + G D YL V W +S Q R Q D Sbjct: 270 ----------PAEQAQTQWIDLGKEQDIYLARVNWRDPQHLSFQRQSRDQKK-----LDL 314 Query: 329 DKTTLVWNCPTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGYKHICQFQKD 388 + TL N H ETS T W F DGS + S++ G++H+ + Sbjct: 315 VEVTLASNQQRVLAH-ETSPT-WVPLHNSL--RFLDDGSILWS--SERTGFQHLYRIDSK 368 Query: 389 RKPEQVCTFITKGAWEVISIEALTSDYLYYISNEYKEMPGGRNLYKIQLTDHTNKKCLSC 448 K +T G W V + A+ E +Y + L ++ Sbjct: 369 GK----AAALTHGNWSVDELLAVDEKAGLAYFRAGIESARESQIYAVPLQGGQPQRLSKA 424 Query: 449 DLNPERCQYYSVSLSKEAKYYQLG-CRGPGLPLYTLHRSTDQKELRVLEDNSALDK---- 503 +S S ++ A Y P L R+ +K ++E++ A K Sbjct: 425 ------PGMHSASFARNASVYVDSWSNNSTPPQIELFRANGEKIATLVENDLADPKHPYA 478 Query: 504 MLQDVQMPSKKLDFIVL----NETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQ----- 554 ++ Q P ++F L +T Y +I P FD +K+YP+ + VY GP SQ Sbjct: 479 RYREAQRP---VEFGTLTAADGKTPLNYSVIKPAGFDPAKRYPVAVYVYGGPASQTVTDS 535 Query: 555 ---KADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAA 611 + D F YLA + +V S D RG+ +G A+ + GT+EV DQ+ Sbjct: 536 WPGRGDHLFN----QYLAQ-QGYVVFSLDNRGTPRRGRDFGGALYGKQGTVEVADQLRGV 590 Query: 612 RQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERY 671 + +VD R+ + GWS GGY+T M+L S + CG+A APV+ W YDS YTERY Sbjct: 591 AWLKQQPWVDPARIGVQGWSNGGYMTLMLLAKASDSYACGVAGAPVTDWGLYDSHYTERY 650 Query: 672 MGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDF 731 M LP D YR + V++ E + LLIHG ADDNV F S + AL G F Sbjct: 651 MDLPARNDA--GYREARVLTHIEGLRS-PLLLIHGMADDNVLFTNSTSLMSALQKRGQPF 707 Query: 732 QAMWYTDEDHGIASSTAHQHIYSHMSHFLQQCF 764 + M Y HG++ + A H Y FL +C Sbjct: 708 ELMTYPGAKHGLSGADA-LHRYRVAEAFLGRCL 739 >5YP1-A nrPDB Length = 745 Score = 190 bits (482), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 178/689 (25%), Positives = 295/689 (42%), Gaps = 80/689 (11%) Query: 99 SISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWIT---W 155 I DY SPD +L YDL K K+ N + T Sbjct: 112 GIVDYQWSPDGKALLFPLG----------GELYFYDLTKSGRDAVRKLTNGGGFATDPKI 161 Query: 156 SQEGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSALWWS 215 S +G ++++ +++ ++T G + I NG+ ++V +EE+ ++ WW+ Sbjct: 162 SPKGGFVSFIRDRNLWAIDLASGKEVQLTRDGSDT-IGNGVAEFVADEEM-DRHTGYWWA 219 Query: 216 PNGTFLAYAQFNDTGVPLIE-YSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSL 274 P+ +A+A+ ++T VP+ + Y Y D + + V YP AG N V+ ++ Sbjct: 220 PDDAAIAFARIDETPVPVQKRYEVYPDRT----EVVEQRYPAAGDHNVRVQLGVI----- 270 Query: 275 SSTTTTIPMQITAPASVTTG---DHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKT 331 P P + G D YL V W R++ Q R Q + +T Sbjct: 271 ------APKTGARPRWIDLGKDPDIYLARVDWRDPQRLTFQRQSRDQKK-----IELIET 319 Query: 332 TLVWNCPTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKP 391 TL T + + ++T W + F DG + S++ G++H+ +D Sbjct: 320 TLTNG--TQRTLVTETSTTWVPLHN--DLRFLKDGRFLWS--SERSGFEHLYVASED--- 370 Query: 392 EQVCTFITKGAWEVISIEAL-TSDYLYYISNEYKEMPGGRNLYKIQLTDHTNKKCLSCDL 450 T +T+G W V S+ A+ + L Y+S ++ ++Y + L+ ++ Sbjct: 371 GSTLTALTQGEWVVDSLLAIDEAAGLAYVSGT-RDGATEAHVYAVPLSGGEPRRLTQA-- 427 Query: 451 NPERCQYYSVSLSKEAKYYQLG-CRGPGLPLYTLHRSTDQKELRVLEDNSALDKM----- 504 ++ + ++ A + LP L ++ D +L L N D Sbjct: 428 ----PGMHAATFARNASVFVDSWSSDTTLPQIELFKA-DGTKLATLLVNDVSDATHPYAK 482 Query: 505 LQDVQMPSKKLDFIVLNETR-FWYQMILPPHFDKSKKYPLLIDVYAGPCSQ--------K 555 + P+ + T Y +I P FD K+YP+++ VY GP +Q + Sbjct: 483 YRAAHQPTAYGTLTAADGTTPLHYSLIKPAGFDPKKQYPVVVFVYGGPAAQTVTRAWPGR 542 Query: 556 ADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFL 615 +D+ F YLA + +V + D RG+ +G A+ + GT+EV+DQ+ Sbjct: 543 SDSFFN----QYLAQ-QGYVVFTLDNRGTPRRGAAFGGALYGKQGTVEVDDQLRGIEWLK 597 Query: 616 KMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLP 675 FVD R+ ++GWS GGY+T M+L + CG+A APV+ W YD+ YTERYM L Sbjct: 598 SQAFVDPARIGVYGWSNGGYMTLMLLAKHDEAYACGVAGAPVTDWALYDTHYTERYMDL- 656 Query: 676 TPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMW 735 P+ N YR ++V + + + LLIHG ADDNV F S ++ L G F+ M Sbjct: 657 -PKANEAGYREASVFTHVDGIGAGKLLLIHGMADDNVLFTNSTKLMSELQKRGTPFELMT 715 Query: 736 YTDEDHGIASSTAHQHIYSHMSHFLQQCF 764 Y HG+ S H Y F +C Sbjct: 716 YPGAKHGLRGSDL-LHRYRLTEDFFARCL 743 >6EOT-A nrPDB Length = 898 Score = 166 bits (419), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 190/703 (27%), Positives = 291/703 (41%), Gaps = 115/703 (16%) Query: 147 PNNTQWITWSQEGHKLAYVWKNDIYVKIEPHLP-SHRITSTGKENVIFNGINDWVYEEEI 205 P + WI + +W ++I + E L H + +E+ G+ +V +EE Sbjct: 222 PADPDWIAFIHSND----IWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEE- 276 Query: 206 FGAYSALWW------SPNGTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGA 259 F YS WW +P+G + + + +E + L+ + YPK G Sbjct: 277 FDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGT 336 Query: 260 VNPTVKFFI--VNTDSLSSTTTTIPMQITAPASVT-TGDHYLCDVAWVSEDRIS------ 310 NP V F + + D+ I ++ P + G Y+ W E + + Sbjct: 337 ANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLD 396 Query: 311 -----------------------LQWLRRIQNY--SVMAICDYDKTTLVW---------N 336 ++ R I++ SV + Y++TT +W Sbjct: 397 RSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVF 456 Query: 337 CPTTQEHIETSATGWCGR-FRPAEPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVC 395 + +E IE C FR + S YK S G F+ K E Sbjct: 457 PQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSG--GLPAPSDFKCPIKEE--- 511 Query: 396 TFITKGAWEVI-----SIEALTSDYLYYISNEYKEMPGGRNLYKI---------QLTD-- 439 IT G WEV+ +I+ L Y K+ P +LY + +LTD Sbjct: 512 IAITSGEWEVLGRHGSNIQVDEVRRLVYFEGT-KDSPLEHHLYVVSYVNPGEVTRLTDRG 570 Query: 440 HTNKKCLSCDLNPERCQYYSVSLSKEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLED-N 498 +++ C+S + C ++ +SK + C + LY L D + E Sbjct: 571 YSHSCCIS-----QHCDFF---ISKYSNQKNPHC----VSLYKLSSPEDDPTCKTKEFWA 618 Query: 499 SALDKM--LQDVQMPSKKLDFIVLNETRF-WYQMILPPH-FDKSKKYPLLIDVYAGPCSQ 554 + LD L D P F + T F Y M+ PH KKYP ++ +Y GP Q Sbjct: 619 TILDSAGPLPDYTPPEI---FSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQ 675 Query: 555 ------KADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQI 608 K FRLN LAS ++V D RGS ++G K A ++G +E++DQ+ Sbjct: 676 LVNNRFKGVKYFRLN---TLASLGYVVVV-IDNRGSCHRGLKFEGAFKYKMGQIEIDDQV 731 Query: 609 EAARQFL--KMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSV 666 E Q+L + F+D RV I GWSYGGY++ M L S +F+ IA APV+ W +YD+ Sbjct: 732 EGL-QYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTG 790 Query: 667 YTERYMGLPTPEDNLDHYRNSTVMSRAENF--KQVEYLLIHGTADDNVHFQQSAQISKAL 724 YTERYMG P+ N Y +V +AE F + LL+HG D+NVHF ++ + L Sbjct: 791 YTERYMG--HPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFL 848 Query: 725 VDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFLQQCFSLR 767 V AG + Y E H I + +H H+ H+LQ+ R Sbjct: 849 VRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSR 891 >2EEP-A nrPDB Length = 706 Score = 159 bits (403), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 162/647 (25%), Positives = 281/647 (43%), Gaps = 69/647 (10%) Query: 133 YDLNKRQLITEEKIPNNTQWITWSQEGHKLAYVWKNDIYVKIEPHLPSHR-----ITSTG 187 +D+ R++ T + +S G ++AYV +++Y+ L +T G Sbjct: 106 FDMLARKVTYLFDTNEETASLDFSPVGDRVAYVRNHNLYIARGGKLGEGMSRAIAVTIDG 165 Query: 188 KENVIFNGINDWVYEEEIFGAYSALWWSPNGTFLAYAQFNDTGV---PLIEYSFYSDESL 244 E +++ V++ E FG +WSP G+ LA+ + + + V P+++Y ES Sbjct: 166 TETLVYG---QAVHQRE-FGIEKGTFWSPKGSCLAFYRMDQSMVKPTPIVDYHPLEAES- 220 Query: 245 QYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSSTTTTIPMQITAPASVTTGDHYLCDVAWV 304 K ++ YP AG + V I + +T T+ +Q P + +L +++W Sbjct: 221 ---KPLY--YPMAGTPSHHVTVGIYHL----ATGKTVYLQTGEPK-----EKFLTNLSWS 266 Query: 305 SEDRI-SLQWLRRIQNYSVMAICDYDKTTLVWN--CPTTQEHIETSATGWCGRFRPAEPH 361 ++ I + + R QN + D + V T + ++E P P Sbjct: 267 PDENILYVAEVNRAQNECKVNAYDAETGRFVRTLFVETDKHYVE-----------PLHPL 315 Query: 362 FTSDGSSFYKI-VSDKDGYKHICQFQKDRKPEQVCTFITKGAWEVISIEAL--TSDYLYY 418 GS+ I S +DG+ H+ + + + +TKG WEV + LY+ Sbjct: 316 TFLPGSNNQFIWQSRRDGWNHLYLYDTTGR---LIRQVTKGEWEVTNFAGFDPKGTRLYF 372 Query: 419 ISNEYKEMPGGRNLYKIQLTDHTNKKCLSCDLNPERCQYYSVSLSKEAKYYQLGCRGPGL 478 S E P R+ Y I + K DL PE + + LS + + P + Sbjct: 373 ESTEAS--PLERHFYCIDIKGGKTK-----DLTPESGMHRT-QLSPDGSAIIDIFQSPTV 424 Query: 479 PLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDFIVL--NETRFWYQMILPPHFD 536 P + + +LE + MP + I+ +T +Y++ +P HFD Sbjct: 425 PRKVTVTNIGKGSHTLLEAKNPD----TGYAMPEIRTGTIMAADGQTPLYYKLTMPLHFD 480 Query: 537 KSKKYPLLIDVYAGPCSQKADAAFRLN---WATYLASTENIIVASFDGRGSGYQGDKIMH 593 +KKYP+++ VY GP +Q +R + W Y+A + V + D RGS +G Sbjct: 481 PAKKYPVIVYVYGGPHAQLVTKTWRSSVGGWDIYMAQ-KGYAVFTVDSRGSANRGAAFEQ 539 Query: 594 AINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIA 653 I++RLG E+ DQ+ +VD+ R+ + GWSYGG++T+ ++ + VFK G+A Sbjct: 540 VIHRRLGQTEMADQMCGVDFLKSQSWVDADRIGVHGWSYGGFMTTNLMLTHGDVFKVGVA 599 Query: 654 VAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVH 713 PV W Y+ +Y ERY P++N + Y + ++ RA + K +LIHG D V Sbjct: 600 GGPVIDWNRYEIMYGERY--FDAPQENPEGYDAANLLKRAGDLKG-RLMLIHGAIDPVVV 656 Query: 714 FQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFL 760 +Q S A V A Y +H + H+Y ++ + Sbjct: 657 WQHSLLFLDACVKARTYPDYYVYPSHEHNVMGPD-RVHLYETITRYF 702 >4Q1V-A nrPDB Length = 710 Score = 155 bits (392), Expect = 6e-38, Method: Compositional matrix adjust. Identities = 158/673 (23%), Positives = 289/673 (42%), Gaps = 84/673 (12%) Query: 121 QWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQEGHKLAYVWKNDIYVKIEPHLPS 180 Q + + +Y+ Q+++ K + + +AY N++YV + Sbjct: 89 QMLFTIAGKFIVYNFKNNQVVSTFKPKDGANNEDYCAASGNVAYTIDNNLYV-------N 141 Query: 181 HRITSTGKENVIFNGINDWVYEEEIFGAYSALWWSPNGTFLAYAQFNDTGV---PLIEYS 237 + + E ++ V+ E FG +WSP G LA+ + +++ V PL+ Sbjct: 142 EKAVTNEPEGIV---CGQTVHRNE-FGINKGTFWSPKGNLLAFYRMDESMVTQYPLV--- 194 Query: 238 FYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSSTTTTIPMQITAPASVTTGDHY 297 D + + + + YP AG + VK I N +T +I + P D Y Sbjct: 195 ---DITARVGEVNNVRYPMAGMTSHQVKVGIYN----PATGKSIYLNAGDPT-----DRY 242 Query: 298 LCDVAWVSEDR-ISLQWLRRIQNYSVMAICDYD-KTTLVWNCPTTQEHIETSATGWCGRF 355 +++W +++ + L + R QN++ +C Y+ +T + H + F Sbjct: 243 FTNISWAPDEKSLYLIEVNRDQNHA--KLCQYNAETGEPMGVLYEEMHPKYVEPQNPIVF 300 Query: 356 RPAEPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVCTFITKGAWEVISIEALTSDY 415 P +P + + S +DGY H+ F+ + + T+ + Sbjct: 301 LPWDP-------TKFIYQSQRDGYNHLYLFETNAANMKGETYNSANGGS----------- 342 Query: 416 LYYISNEYKEMPGGRNLYKIQLTDHTNKK-CLSCDLNPERCQYYSVSLS----------- 463 Y+ + + K++ G L L +T +K + + R +++V++S Sbjct: 343 -YFQAGKVKQLTKGNWLVSEILGFNTKRKEVIFTAVEGLRSGHFAVNVSNGKISQPFENC 401 Query: 464 KEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKMLQ---------DVQMPSKK 514 KE+++ G L + + DQ + L D + QMPS + Sbjct: 402 KESEHSGT-LSASGTYLIDRYSTKDQPRVINLVDTKNFKETANLLTAENPYDGYQMPSIE 460 Query: 515 LDFIVLNE--TRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFR---LNWATYLA 569 I + T Y+++ P +FD +KKYP+++ VY GP +Q ++ W TY+A Sbjct: 461 TGTIKAADGTTDLHYRLMKPANFDPAKKYPVIVYVYGGPHAQCVTGGWQNGARGWDTYMA 520 Query: 570 STENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWG 629 S + I+ + D RGS +G +A +RLG E +DQ++ + +VDS+R+ + G Sbjct: 521 S-KGYIMFTIDNRGSSNRGLTFENATFRRLGIEEGKDQVKGVEFLKSLPYVDSERIGVHG 579 Query: 630 WSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTV 689 WS+GG++T+ ++ +FK G+A PV W YY+ +Y ERYM TPE N + Y+ + Sbjct: 580 WSFGGHMTTALMLRYPEIFKVGVAGGPVIDWGYYEIMYGERYMD--TPESNPEGYKECNL 637 Query: 690 MSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAH 749 + A+ K L+IH DD Q + KA VDA Y H +A Sbjct: 638 KNLADQLKG-HLLIIHDDHDDTCVPQHTLSFMKACVDARTYPDLFIYPCHKHNVAGRD-R 695 Query: 750 QHIYSHMSHFLQQ 762 H++ ++ + +Q Sbjct: 696 VHLHEKITRYFEQ 708 >6EOR-A nrPDB Length = 869 Score = 150 bits (380), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 99/264 (37%), Positives = 140/264 (53%), Gaps = 19/264 (7%) Query: 510 MPSKKLDFIVLNETRFWYQMILPPH-FDKSKKYPLLIDVYAGPCSQKADAAF------RL 562 +P + F ++ R Y MI PH KK+P ++ VY GP Q + +F RL Sbjct: 606 VPPEIFHFHTRSDVRL-YGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRL 664 Query: 563 NWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFL--KMGFV 620 N LAS +V DGRGS +G + A+ ++G +E+EDQ+E QF+ K GF+ Sbjct: 665 N---TLASLGYAVVV-IDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGL-QFVAEKYGFI 719 Query: 621 DSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDN 680 D RVAI GWSYGG+++ M L VFK IA APV+ W YD+ YTERYM + PE+N Sbjct: 720 DLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDV--PENN 777 Query: 681 LDHYRNSTVMSRAENF--KQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTD 738 Y +V E + L++HG D+NVHF + + L+ AG +Q Y + Sbjct: 778 QHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPN 837 Query: 739 EDHGIASSTAHQHIYSHMSHFLQQ 762 E H I + +H + HFLQ+ Sbjct: 838 ERHSIRCPESGEHYEVTLLHFLQE 861 Score = 29.6 bits (65), Expect = 5.3, Method: Compositional matrix adjust. Identities = 63/308 (20%), Positives = 113/308 (36%), Gaps = 38/308 (12%) Query: 31 DEAAADSRRTYTLADYLKNTFRVKSYSLRWVSDSEYLYKQENNILL--------FNA--E 80 DE+ S R Y YL + + SL + S+ ++E +LL F A Sbjct: 63 DESGPHSHRLY----YLGMPYGSRENSLLY-SEIPKKVRKEALLLLSWKQMLDHFQATPH 117 Query: 81 HG----NSSIFLENSTFEIFGDSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLN 136 HG + E +FG + D+ S LF+ N + R + + + Sbjct: 118 HGVYSREEELLRERKRLGVFGITSYDFH-SESGLFLFQASNSLFHCRDGGKNGFMVSPMK 176 Query: 137 KRQLITEEKIPNNTQWITWSQEGHKLAYVWKNDIYVKIEPHLPSHRIT--STGKENVIFN 194 ++ T+ P I + +++ +D++V R+T G NV+ + Sbjct: 177 PLEIKTQCSGPRMDPKICPADPAF-FSFINNSDLWVANIETGEERRLTFCHQGLSNVLDD 235 Query: 195 ----GINDWVYEEEIFGAYSALWWSPNGTFLAYAQFNDTGVPLIEYSFYSDESLQYP--- 247 G+ +V +EE F ++ WW P ++ + E E + P Sbjct: 236 PKSAGVATFVIQEE-FDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPA 294 Query: 248 ----KTVWIPYPKAGAVNPTV--KFFIVNTDSLSSTTTTIPMQITAP-ASVTTGDHYLCD 300 KT YP+ G+ NP + K TDS +T ++ P +S+ Y+ Sbjct: 295 LEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIAR 354 Query: 301 VAWVSEDR 308 W + + Sbjct: 355 AGWTRDGK 362 >4HXF-B nrPDB Length = 622 Score = 65.5 bits (158), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 61/243 (25%), Positives = 111/243 (45%), Gaps = 17/243 (6%) Query: 526 WYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGS- 584 WY + P + +K P+++ V+ GP K + + L +++ + + RGS Sbjct: 366 WY---IKPEIKEGEKAPVIVFVHGGP---KGMYGYYFKYEMQLMASKGYYIVYVNPRGSN 419 Query: 585 GYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMG-FVDSKRVAIWGWSYGGYVTSMVLGS 643 GY D + + +R G + +D + +FL++ D +R+ I G SYGGY+T+ L + Sbjct: 420 GYSEDFALRVL-ERTGLEDFQDILNGIEEFLRLEPQADRERIGITGISYGGYMTNWAL-T 477 Query: 644 GSGVFKCGIAVAPVSRW----EYYD-SVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQ 698 S +FK GI+ +S W + D ++ ++ + P +N ++YR + + A+N K Sbjct: 478 QSDLFKAGISENGISYWLTSYAFSDIGLWFDKEVIGDNPLEN-ENYRKLSPLFYAKNVK- 535 Query: 699 VEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMSH 758 LLIH D QS L D G + + HG + + +H Sbjct: 536 APLLLIHSLEDYRCPLDQSLMFYHVLKDLGKEVYIAIFKKGAHGHSIRGSPRHRMKRYKL 595 Query: 759 FLQ 761 F++ Sbjct: 596 FME 598 >5L8S-A nrPDB Length = 604 Score = 62.8 bits (151), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 99/485 (20%), Positives = 195/485 (40%), Gaps = 53/485 (10%) Query: 291 VTTGDHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTTLVWNCPTTQEHIETSATG 350 + G+ ++A VSE+ S +LR N ++ + T +N E + + Sbjct: 149 LNVGEVSTTELAAVSENEESFVYLRAFANTYIVGFVKMGEET--FNITPDPEKVHVAM-- 204 Query: 351 WCGRFRPAEPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVCTFITKGAWEVISIEA 410 EP FT + + ++ D D ++ +F D ++ + + S++ Sbjct: 205 --------EPVFTDNETIYFATDYDSDEM-YLAKF--DLTSKEFSKVLAFDGESIQSVKW 253 Query: 411 LTSDYLYYISNEYKEMPGGRN-LYKIQL-TDHTNKKCLSCDLNPERCQYYSVSLSKEAKY 468 + +Y+ + G + LY+ + TD + L D+ + + ++K Sbjct: 254 DKDNKAFYLIT----VKGVTDILYRYDVATDKVEECSLPVDIIEQ------IQVAKSGNL 303 Query: 469 YQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDFIVLNETRF--- 525 Y LG R +P + +++S++ E + L +N L +D+ P +++ T F Sbjct: 304 YILG-RSATVP-HNVYQSSNGVEWKQLTNNRVLGLSPEDMVEPD------IVSYTSFDGM 355 Query: 526 -WYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGS 584 ++ + Y + + GP S + FR + ++ I +F RGS Sbjct: 356 EIEALLFKAKPENDNGYTIFWP-HGGPQSAER-KMFRSMFQCFINRGYTIFAPNF--RGS 411 Query: 585 GYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSG 644 G + G D I + GF D ++ + G SYGGY+ ++ G Sbjct: 412 TGYGSAFTKLVELDWGEGPRLDCIAGIEWLFESGFTDRNKLFLVGGSYGGYMALLLHGRH 471 Query: 645 SGVFKCGIAV-APVSRWEYYDSV------YTERYMGLPTPEDNLDHYRNSTVMSRAENFK 697 S F+ + + P + + +SV ER++G PE + + + + ++ + Sbjct: 472 SDYFRAVVDIFGPSDLFTFINSVPPHWKPIMERWLG--DPERDKERFIKDSPVTYLDGMV 529 Query: 698 QVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMS 757 + L+I G D V ++S QI L + G D + + DE HG + +YS M Sbjct: 530 K-PMLVIQGAKDPRVVKEESDQIVAKLKEKGRDVEYLVLEDEGHGFSKKENEIKVYSLML 588 Query: 758 HFLQQ 762 FL++ Sbjct: 589 AFLEK 593 >3O4I-A nrPDB Length = 582 Score = 49.3 bits (116), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 54/213 (25%), Positives = 95/213 (44%), Gaps = 26/213 (12%) Query: 542 PLLIDVYAGPCSQKADAAFRLNWATYLASTE----NIIVASFDGRGSGYQGDKIMHAINK 597 P ++ V+ GP ++ +D +W T+ AS ++++ ++ G +GY + + I Sbjct: 361 PTVVLVHGGPFAEDSD-----SWDTFAASLAAAGFHVVMPNYRGS-TGYGEEWRLKIIGD 414 Query: 598 RLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPV 657 G E+ED AAR + G + + I G+SYGGY+T L G+FK G+A A V Sbjct: 415 PCGG-ELEDVSAAARWARESGL--ASELYIMGYSYGGYMTLCALTMKPGLFKAGVAGASV 471 Query: 658 SRW----EYYDSV---YTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADD 710 W E D+ + E+ G + + R+ + ++ + K+ LIH Sbjct: 472 VDWEEMYELSDAAFRNFIEQLTG-----GSREIMRSRSPINHVDRIKE-PLALIHPQNAS 525 Query: 711 NVHFQQSAQISKALVDAGVDFQAMWYTDEDHGI 743 + ++ L+ G F+A D H I Sbjct: 526 RTPLKPLLRLMGELLARGKTFEAHIIPDAGHAI 558 >3AZQ-A nrPDB Length = 662 Score = 48.9 bits (115), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 59/246 (23%), Positives = 105/246 (42%), Gaps = 20/246 (8%) Query: 511 PSKKLDFIVLNETRFWYQMILPPH-----FDKSKKYPLLIDVYAGPCSQKADAAFRLNWA 565 P ++ + R + I PPH + P ++ + GP S + A L+ A Sbjct: 389 PEPQIRTFTAPDGREIHAHIYPPHSPDFTGPADELPPYVVMAHGGPTS-RVPAVLDLDVA 447 Query: 566 TYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRV 625 + ++ I VA + GS G + R G ++VED A + G D R+ Sbjct: 448 YF--TSRGIGVADVNYGGSTGYGRAYRERLRGRWGVVDVEDCAAVATALAEEGTADRARL 505 Query: 626 AIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPV--------SRWEYYDSVYTERYMGLPTP 677 A+ G + GG+ + L S + V+ CG + PV ++S Y + +G + Sbjct: 506 AVRGGAAGGWTAASSLVS-TDVYACGTVLYPVLDLLGWADGGTHDFESRYLDFLIG--SF 562 Query: 678 EDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYT 737 E+ + YR+ ++RA+ + V +LL+ G D +Q + +A+ GV + + Sbjct: 563 EEFPERYRDRAPLTRADRVR-VPFLLLQGLEDPVCPPEQCDRFLEAVAGCGVPHAYLSFE 621 Query: 738 DEDHGI 743 E HG Sbjct: 622 GEGHGF 627 >5UW6-A nrPDB Length = 750 Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 33/148 (22%), Positives = 57/148 (38%), Gaps = 15/148 (10%) Query: 520 LNETRFWYQMILPPHFDKSKKYPLLIDVYAG-------PCSQKADAAFRLNWATYLASTE 572 + + F + + P D +K P+ I G PC F +N +++ Sbjct: 464 FDRSEFEVKQVFVPSKDGTK-IPIFIAARKGISLDGSHPCEMHGYGGFGINMMPTFSASR 522 Query: 573 NIIVASFDG-------RGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRV 625 + + G RG G G++ A + +D I AA + G+ ++RV Sbjct: 523 IVFLKHLGGVFCLANIRGGGEYGEEWHKAGFRDKKQNVFDDFISAAEYLISSGYTKARRV 582 Query: 626 AIWGWSYGGYVTSMVLGSGSGVFKCGIA 653 AI G S GG + + + +F C A Sbjct: 583 AIEGGSNGGLLVAACINQRPDLFGCAEA 610 >6IGR-A nrPDB Length = 656 Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust. Identities = 57/250 (22%), Positives = 106/250 (42%), Gaps = 24/250 (9%) Query: 508 VQMPSKKLDFIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATY 567 V+ P + L E W ++LP + +K P L++++ GP + D Sbjct: 399 VREPQRVTFETELGEGEGW--VLLP---EGEQKVPALLNIHGGPHT---DYGHGFTHEFQ 450 Query: 568 LASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLK-MGFVDSKRVA 626 L + V + RGS G + AI R GT++ +D + + L+ + +D+ + A Sbjct: 451 LMAARGYGVCYSNPRGSVGYGQAWVDAIYGRWGTVDADDLLNFFDRCLEAVPRLDAAKTA 510 Query: 627 IWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPED--NLDHY 684 + G +YGG++T+ + G + F+ I +S + +GL +D LD Sbjct: 511 VMGGAYGGFMTNWITGHTT-RFQAAITDRCISNLISFGGTSD---IGLRFWDDELGLDFS 566 Query: 685 RNSTVMSR--------AENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWY 736 R + + EN K L++H D +Q+ Q AL V + + + Sbjct: 567 RRADALKLWDLSPLQYVENVK-TPTLIVHSVLDHRCPVEQAEQWYAALHKHQVPVRFVRF 625 Query: 737 TDEDHGIASS 746 +E+H ++ S Sbjct: 626 PEENHELSRS 635 >3DYV-A nrPDB Length = 251 Score = 36.2 bits (82), Expect = 0.059, Method: Compositional matrix adjust. Identities = 39/158 (24%), Positives = 68/158 (43%), Gaps = 23/158 (14%) Query: 624 RVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYD-------SVYTERYMG--- 673 +V ++G S GG L + G+ G+ +P+ +++ + Y R G Sbjct: 94 KVFVFGLSLGGIFAMKALETLPGITAGGVFSSPILPGKHHLVPGFLKYAEYMNRLAGKSD 153 Query: 674 --------LPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALV 725 LP +D + +TV + KQ ++ G D+ V + + Q+ AL+ Sbjct: 154 ESTQILAYLPGQLAAIDQFA-TTVAADLNLVKQPTFIGQAGQ-DELVDGRLAYQLRDALI 211 Query: 726 DAG-VDFQAMWYTDEDHGIASSTAHQHIYSHMSHFLQQ 762 +A VDF WY D H I ++AH + + F+QQ Sbjct: 212 NAARVDFH--WYDDAKHVITVNSAHHALEEDVIAFMQQ 247 >2D81-A nrPDB Length = 318 Score = 34.3 bits (77), Expect = 0.22, Method: Compositional matrix adjust. Identities = 31/112 (27%), Positives = 51/112 (45%), Gaps = 10/112 (8%) Query: 620 VDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAV---AP--VSRWEYYDSVYTERYMGL 674 V+ V++ G + GGY+ + + + S VF G V P +R +YY S Y + Sbjct: 8 VNPNSVSVSGLASGGYMAAQLGVAYSDVFNVGFGVFAGGPYDCARNQYYTSCMYNGYPSI 67 Query: 675 PTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADD----NVHFQQSAQISK 722 TP N+ + + + S A N Q + + G++D NV Q AQ+ Sbjct: 68 TTPTANMKSWSGNQIASVA-NLGQRKIYMWTGSSDTTVGPNVMNQLKAQLGN 118 >3KSR-A nrPDB Length = 290 Score = 33.5 bits (75), Expect = 0.36, Method: Compositional matrix adjust. Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 6/67 (8%) Query: 575 IVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAA-RQFLKMGFVDSKRVAIWGWSYG 633 I +FD RG ++G M R L D I+AA Q + +VD+ +A+ G SYG Sbjct: 57 ICMTFDLRG--HEGYASMRQSVTRAQNL---DDIKAAYDQLASLPYVDAHSIAVVGLSYG 111 Query: 634 GYVTSMV 640 GY+++++ Sbjct: 112 GYLSALL 118 >2BKL-A nrPDB Length = 695 Score = 31.2 bits (69), Expect = 1.7, Method: Compositional matrix adjust. Identities = 38/144 (26%), Positives = 59/144 (40%), Gaps = 10/144 (6%) Query: 542 PLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGT 601 P L+ Y G + +A FR + +L + VA+ RG G G K H + Sbjct: 447 PTLLYGYGG-FNVNMEANFRSSILPWLDAGGVYAVANL--RGGGEYG-KAWHDAGRLDKK 502 Query: 602 LEVEDQIEAARQFL-KMGFVDSKRVAIWGWSYGGYVTSMVLGSGS---GVFKCGIAVAPV 657 V D AA ++L + + KR+AI+G S GG + + G C + + + Sbjct: 503 QNVFDDFHAAAEYLVQQKYTQPKRLAIYGGSNGGLLVGAAMTQRPELYGAVVCAVPLLDM 562 Query: 658 SRWEYYDSVYT--ERYMGLPTPED 679 R+ + S T Y PED Sbjct: 563 VRYHLFGSGRTWIPEYGTAEKPED 586 >1NW1-A nrPDB Length = 429 Score = 30.0 bits (66), Expect = 3.9, Method: Compositional matrix adjust. Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 9/94 (9%) Query: 70 QENNILLFNAEHGNSSIFLENSTFEIFGDSISDYSVSPDRLFVLLEYNYVK-QWRHSYTA 128 QE NILL A GN + + + G+S+S ++ + RL VL+++ Y +R A Sbjct: 257 QEGNILLPKASSGNIRMPSLSDETQALGNSLSAFNPADPRL-VLIDFEYASYNYRAFDFA 315 Query: 129 SYSI-----YDLNKRQL--ITEEKIPNNTQWITW 155 ++ I YD+++ I E P N Q + + Sbjct: 316 NHFIEWTIDYDIDEAPFYKIQTENFPENDQMLEF 349 >1LTX-R nrPDB Length = 650 Score = 30.0 bits (66), Expect = 3.9, Method: Compositional matrix adjust. Identities = 13/47 (27%), Positives = 28/47 (59%) Query: 234 IEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSSTTTT 280 +EY + DE Y T + Y K + P +++F++++ +++S TT+ Sbjct: 300 VEYEEHPDEYRAYEGTTFSEYLKTQKLTPNLQYFVLHSIAMTSETTS 346 >3TM5-A nrPDB Length = 373 Score = 30.0 bits (66), Expect = 4.1, Method: Compositional matrix adjust. Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 3/45 (6%) Query: 669 ERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVH 713 ER TP NLDH V+ RAE K V +L I T D ++H Sbjct: 148 ERLSRFGTPLVNLDH---PAVIFRAELIKDVFFLGIDTTGDSSLH 189 >5T88-A nrPDB Length = 616 Score = 30.0 bits (66), Expect = 4.4, Method: Compositional matrix adjust. Identities = 49/204 (24%), Positives = 71/204 (34%), Gaps = 11/204 (5%) Query: 567 YLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVA 626 +L I+A+ G GS Y + H R V D A + LK + +VA Sbjct: 419 FLKRGGTFIMANLRG-GSEYGEE--WHRAGMRENKQNVFDDFIAVLEKLKK---EGYKVA 472 Query: 627 IWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVS---RWE--YYDSVYTERYMGLPTPEDNL 681 WG S GG + S L V + PV R+ Y SV+ Y P+D Sbjct: 473 AWGRSNGGLLVSATLTQRPDVMDSALIGYPVIDMLRFHKLYIGSVWIPEYGNPEDPKDRE 532 Query: 682 DHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDH 741 + S + K L+ G DD VH + + L + G T H Sbjct: 533 FLLKYSPYHNVDPKKKYPPTLIYTGLHDDRVHPAHALKFFMKLKEIGAPVYLRVETKSGH 592 Query: 742 GIASSTAHQHIYSHMSHFLQQCFS 765 AS + + F+ + S Sbjct: 593 MGASPETRARELTDLLAFVLKTLS 616 >4GGR-A nrPDB Length = 115 Score = 29.6 bits (65), Expect = 5.8, Method: Compositional matrix adjust. Identities = 13/27 (48%), Positives = 18/27 (66%) Query: 252 IPYPKAGAVNPTVKFFIVNTDSLSSTT 278 IPYP AG+V+PT +F+V +S T Sbjct: 50 IPYPAAGSVSPTGLYFVVTFAQCNSFT 76 >6HIS-A nrPDB Length = 445 Score = 29.3 bits (64), Expect = 6.0, Method: Compositional matrix adjust. Identities = 15/42 (35%), Positives = 22/42 (52%), Gaps = 4/42 (9%) Query: 389 RKPEQV----CTFITKGAWEVISIEALTSDYLYYISNEYKEM 426 R PE+V FI +G WE++ + ++ ISN Y EM Sbjct: 162 RSPEEVRSDKSIFINQGEWELLEVFPQFKEFSIDISNSYAEM 203 >4YB9-D nrPDB Length = 479 Score = 29.3 bits (64), Expect = 7.2, Method: Compositional matrix adjust. Identities = 15/41 (36%), Positives = 25/41 (60%), Gaps = 8/41 (19%) Query: 5 WKVLLGLLGVAALVTIITVP--------VVLLNKDEAAADS 37 W +LLGL G+ A++ ++ +P +++ KDEAAA S Sbjct: 192 WPILLGLTGIPAVLQLLFLPFFPESPRYLLIQKKDEAAAKS 232 >3IVU-A nrPDB Length = 423 Score = 29.3 bits (64), Expect = 7.5, Method: Compositional matrix adjust. Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 2/47 (4%) Query: 687 STVMSRAENFKQVEYLLIHGTADDNVHF--QQSAQISKALVDAGVDF 731 S +SR NF +E L G N F ++ QI+KAL + GVD+ Sbjct: 31 SDFLSRVNNFSIIESTLREGEQFANAFFDTEKKIQIAKALDNFGVDY 77 >4GAA-A nrPDB Length = 609 Score = 28.9 bits (63), Expect = 8.0, Method: Compositional matrix adjust. Identities = 14/38 (36%), Positives = 23/38 (60%), Gaps = 1/38 (2%) Query: 282 PMQITAPASVTTGDHYLCDVAWVSEDRIS-LQWLRRIQ 318 P++IT P S+T G + ++ V+ + S LQWL + Q Sbjct: 82 PLEITLPFSLTRGQEVIVEIDSVTSPKSSALQWLNKEQ 119 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2QT9-A nrPDB 1062 0.0 2GBG-A nrPDB 1047 0.0 2AJB-A nrPDB 1007 0.0 1Z68-A nrPDB 872 0.0 4WJL-A nrPDB 804 0.0 1XFD-A nrPDB 784 0.0 5OLJ-A nrPDB 687 0.0 5YP1-A nrPDB 616 e-176 2ECF-A nrPDB 612 e-175 4Q1V-A nrPDB 572 e-163 2EEP-A nrPDB 562 e-160 6EOT-A nrPDB 501 e-142 6EOR-A nrPDB 396 e-110 5L8S-A nrPDB 365 e-101 4HXF-B nrPDB 215 5e-56 3AZQ-A nrPDB 208 6e-54 3O4I-A nrPDB 185 7e-47 5UW6-A nrPDB 143 2e-34 Sequences not found previously or not previously below threshold: 6IGR-A nrPDB 153 3e-37 5T88-A nrPDB 123 3e-28 4AMY-A nrPDB 121 1e-27 2BKL-A nrPDB 114 2e-25 1YR2-A nrPDB 111 1e-24 3MUN-A nrPDB 104 1e-22 4HVT-A nrPDB 93 7e-19 5N4B-A nrPDB 90 5e-18 4BP8-A nrPDB 86 7e-17 2XE4-A nrPDB 80 3e-15 3WYD-A nrPDB 78 2e-14 5TXC-A nrPDB 74 3e-13 5AOA-A nrPDB 73 5e-13 5JRK-A nrPDB 67 3e-11 4Q3K-A nrPDB 59 6e-09 1C7J-A nrPDB 58 1e-08 3KSR-A nrPDB 58 2e-08 3FCY-A nrPDB 55 1e-07 5V5V-A nrPDB 54 3e-07 2HDW-A nrPDB 51 2e-06 6AVW-A nrPDB 51 2e-06 6AAE-A nrPDB 51 2e-06 6GI5-A nrPDB 49 5e-06 3HXK-A nrPDB 49 1e-05 4V2I-A nrPDB 49 1e-05 3DYV-A nrPDB 48 1e-05 5XB6-A nrPDB 48 2e-05 2OCI-A nrPDB 47 3e-05 3HEA-A nrPDB 47 4e-05 6FKX-A nrPDB 46 5e-05 6GUD-A nrPDB 46 6e-05 2XLB-A nrPDB 46 8e-05 5HFN-A nrPDB 45 1e-04 5X6S-A nrPDB 45 1e-04 5DWD-A nrPDB 44 2e-04 1THG-A nrPDB 44 2e-04 3FCX-A nrPDB 44 2e-04 3E4D-A nrPDB 44 3e-04 2WQZ-A nrPDB 43 4e-04 3BIX-A nrPDB 43 4e-04 1C5K-A nrPDB 43 6e-04 3I6Y-A nrPDB 43 7e-04 3RAR-A nrPDB 43 7e-04 1K4Y-A nrPDB 42 8e-04 4B6G-A nrPDB 42 8e-04 3LS2-A nrPDB 42 9e-04 4BZW-A nrPDB 42 9e-04 4NOX-A nrPDB 42 0.001 3RLI-A nrPDB 41 0.001 5XKS-A nrPDB 41 0.001 2D81-A nrPDB 41 0.001 2W6C-X nrPDB 41 0.002 2X8B-A nrPDB 41 0.002 5FV4-A nrPDB 40 0.003 1MX5-A nrPDB 40 0.003 4PF1-A nrPDB 40 0.004 5FDF-A nrPDB 40 0.004 4WY5-A nrPDB 40 0.005 4R40-A nrPDB 40 0.005 4WY8-A nrPDB 39 0.006 1Q83-A nrPDB 39 0.007 2YH2-A nrPDB 39 0.008 1LLF-A nrPDB 39 0.008 2C7B-A nrPDB 39 0.009 2JBW-A nrPDB 39 0.010 4DGQ-A nrPDB 38 0.014 3WMR-A nrPDB 38 0.020 1R88-A nrPDB 37 0.026 1MPX-A nrPDB 37 0.030 5L2P-A nrPDB 37 0.040 3FNB-A nrPDB 37 0.041 5K1H-B nrPDB 36 0.052 1UFO-A nrPDB 36 0.065 1LNS-A nrPDB 36 0.070 1GZ7-A nrPDB 36 0.076 4HZN-A nrPDB 36 0.077 6EIC-C nrPDB 35 0.14 5LZ5-A nrPDB 35 0.14 3N0T-A nrPDB 35 0.15 1NX9-A nrPDB 35 0.15 3WLA-A nrPDB 34 0.17 1AZW-A nrPDB 34 0.19 4G5X-A nrPDB 34 0.24 1DIN-A nrPDB 34 0.24 6EMI-A nrPDB 34 0.24 1ODT-C nrPDB 34 0.26 5HQ3-A nrPDB 34 0.27 1BU8-A nrPDB 34 0.34 1HPL-A nrPDB 34 0.36 6AGQ-A nrPDB 33 0.38 3FM0-A nrPDB 33 0.43 2PPL-A nrPDB 33 0.49 5W8P-A nrPDB 33 0.50 1RP1-A nrPDB 33 0.55 3FOB-A nrPDB 33 0.56 5XMC-A nrPDB 33 0.60 4ZWN-A nrPDB 32 0.65 3GBG-A nrPDB 32 0.79 6QAA-A nrPDB 32 0.89 5CXX-A nrPDB 32 0.90 5THM-A nrPDB 32 1.1 3MGA-A nrPDB 31 2.2 2E3J-A nrPDB 31 2.5 2B20-A nrPDB 31 2.5 4YB9-D nrPDB 31 2.8 3NC3-A nrPDB 30 3.2 5MP7-A nrPDB 30 4.9 >2QT9-A nrPDB Length = 766 Score = 1062 bits (2747), Expect = 0.0, Method: Composition-based stats. Identities = 650/768 (84%), Positives = 705/768 (91%), Gaps = 5/768 (0%) Query: 1 MKTPWKVLLGLLGVAALVTIITVPVVLLNK--DEAAADSRRTYTLADYLKNTFRVKSYSL 58 MKTPWKVLLGLLG AALVTIITVPVVLLNK D+A AD+R+TYTL DYLKNT+R+K YSL Sbjct: 1 MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADTRKTYTLTDYLKNTYRLKLYSL 60 Query: 59 RWVSDSEYLYKQENNILLFNAEHGNSSIFLENSTFEIFGDSISDYSVSPDRLFVLLEYNY 118 RW+SD EYLYKQENNIL+FNAE+GNSS+FLENSTF+ FG SI+DYS+SPD F+LLEYNY Sbjct: 61 RWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNY 120 Query: 119 VKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQEGHKLAYVWKNDIYVKIEPHL 178 VKQWRHSYTASY IYDLNKRQLITEE+IPNNTQW+TWS GHKLAYVW NDIYVKIEP+L Sbjct: 121 VKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNL 180 Query: 179 PSHRITSTGKENVIFNGINDWVYEEEIFGAYSALWWSPNGTFLAYAQFNDTGVPLIEYSF 238 PS+RIT TGKE++I+NGI DWVYEEE+F AYSALWWSPNGTFLAYAQFNDT VPLIEYSF Sbjct: 181 PSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSF 240 Query: 239 YSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSSTTTTIPMQITAPASVTTGDHYL 298 YSDESLQYPKTV +PYPKAGAVNPTVKFF+VNTDSLSS T +QITAPAS+ GDHYL Sbjct: 241 YSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYL 300 Query: 299 CDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTTLVWNCPTTQEHIETSATGWCGRFRPA 358 CDV W +++RISLQWLRRIQNYSVM ICDYD+++ WNC ++HIE S TGW GRFRP+ Sbjct: 301 CDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPS 360 Query: 359 EPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVCTFITKGAWEVISIEALTSDYLYY 418 EPHFT DG+SFYKI+S+++GY+HIC FQ D+K CTFITKG WEVI IEALTSDYLYY Sbjct: 361 EPHFTLDGNSFYKIISNEEGYRHICYFQIDKKD---CTFITKGTWEVIGIEALTSDYLYY 417 Query: 419 ISNEYKEMPGGRNLYKIQLTDHTNKKCLSCDLNPERCQYYSVSLSKEAKYYQLGCRGPGL 478 ISNEYK MPGGRNLYKIQL+D+T CLSC+LNPERCQYYSVS SKEAKYYQL C GPGL Sbjct: 418 ISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGL 477 Query: 479 PLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDFIVLNETRFWYQMILPPHFDKS 538 PLYTLH S + K LRVLEDNSALDKMLQ+VQMPSKKLDFI+LNET+FWYQMILPPHFDKS Sbjct: 478 PLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKS 537 Query: 539 KKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKR 598 KKYPLL+DVYAGPCSQKAD FRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAIN+R Sbjct: 538 KKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRR 597 Query: 599 LGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVS 658 LGT EVEDQIEAARQF KMGFVD+KR+AIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVS Sbjct: 598 LGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVS 657 Query: 659 RWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSA 718 RWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSA Sbjct: 658 RWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSA 717 Query: 719 QISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFLQQCFSL 766 QISKALVD GVDFQAMWYTDEDHGIASSTAHQHIY+HMSHF++QCFSL Sbjct: 718 QISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSL 765 >2GBG-A nrPDB Length = 730 Score = 1047 bits (2707), Expect = 0.0, Method: Composition-based stats. Identities = 730/730 (100%), Positives = 730/730 (100%) Query: 38 RRTYTLADYLKNTFRVKSYSLRWVSDSEYLYKQENNILLFNAEHGNSSIFLENSTFEIFG 97 RRTYTLADYLKNTFRVKSYSLRWVSDSEYLYKQENNILLFNAEHGNSSIFLENSTFEIFG Sbjct: 1 RRTYTLADYLKNTFRVKSYSLRWVSDSEYLYKQENNILLFNAEHGNSSIFLENSTFEIFG 60 Query: 98 DSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQ 157 DSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQ Sbjct: 61 DSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQ 120 Query: 158 EGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSALWWSPN 217 EGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSALWWSPN Sbjct: 121 EGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSALWWSPN 180 Query: 218 GTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSST 277 GTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSST Sbjct: 181 GTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSST 240 Query: 278 TTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTTLVWNC 337 TTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTTLVWNC Sbjct: 241 TTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTTLVWNC 300 Query: 338 PTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVCTF 397 PTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVCTF Sbjct: 301 PTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVCTF 360 Query: 398 ITKGAWEVISIEALTSDYLYYISNEYKEMPGGRNLYKIQLTDHTNKKCLSCDLNPERCQY 457 ITKGAWEVISIEALTSDYLYYISNEYKEMPGGRNLYKIQLTDHTNKKCLSCDLNPERCQY Sbjct: 361 ITKGAWEVISIEALTSDYLYYISNEYKEMPGGRNLYKIQLTDHTNKKCLSCDLNPERCQY 420 Query: 458 YSVSLSKEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDF 517 YSVSLSKEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDF Sbjct: 421 YSVSLSKEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDF 480 Query: 518 IVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVA 577 IVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVA Sbjct: 481 IVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVA 540 Query: 578 SFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVT 637 SFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVT Sbjct: 541 SFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVT 600 Query: 638 SMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFK 697 SMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFK Sbjct: 601 SMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFK 660 Query: 698 QVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMS 757 QVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMS Sbjct: 661 QVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMS 720 Query: 758 HFLQQCFSLR 767 HFLQQCFSLR Sbjct: 721 HFLQQCFSLR 730 >2AJB-A nrPDB Length = 728 Score = 1007 bits (2603), Expect = 0.0, Method: Composition-based stats. Identities = 598/730 (81%), Positives = 649/730 (88%), Gaps = 3/730 (0%) Query: 37 SRRTYTLADYLKNTFRVKSYSLRWVSDSEYLYKQENNILLFNAEHGNSSIFLENSTFEIF 96 SRRTYTL DYLK+TFRVK Y+L+W+SD EYLYKQENNILLFNAE+GNSSIFLENSTF+ Sbjct: 1 SRRTYTLTDYLKSTFRVKFYTLQWISDHEYLYKQENNILLFNAEYGNSSIFLENSTFDEL 60 Query: 97 GDSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWS 156 G S +DYSVSPDR F+L EYNYVKQWRHSYTASY IYDLNKRQLITEE+IPNNTQWITWS Sbjct: 61 GYSTNDYSVSPDRQFILFEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWITWS 120 Query: 157 QEGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSALWWSP 216 GHKLAYVW NDIYVK EP+L S RIT TGKENVI+NG+ DWVYEEE+F AYSALWWSP Sbjct: 121 PVGHKLAYVWNNDIYVKNEPNLSSQRITWTGKENVIYNGVTDWVYEEEVFSAYSALWWSP 180 Query: 217 NGTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSS 276 NGTFLAYAQFNDT VPLIEYSFYSDESLQYPKTV IPYPKAGA NPTVKFF+V+T +LS Sbjct: 181 NGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRIPYPKAGAENPTVKFFVVDTRTLSP 240 Query: 277 TTTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTTLVWN 336 + QI PASV GDHYLC V WV+E+RISLQW+RR QNYS++ ICDYD++T W Sbjct: 241 NASVTSYQIVPPASVLIGDHYLCGVTWVTEERISLQWIRRAQNYSIIDICDYDESTGRWI 300 Query: 337 CPTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVCT 396 ++HIE S TGW GRFRPAEPHFTSDG+SFYKI+S+++GYKHIC FQ D+ CT Sbjct: 301 SSVARQHIEISTTGWVGRFRPAEPHFTSDGNSFYKIISNEEGYKHICHFQTDKSN---CT 357 Query: 397 FITKGAWEVISIEALTSDYLYYISNEYKEMPGGRNLYKIQLTDHTNKKCLSCDLNPERCQ 456 FITKGAWEVI IEALTSDYLYYISNE+K MPGGRNLY+IQL D+T CLSC+LNPERCQ Sbjct: 358 FITKGAWEVIGIEALTSDYLYYISNEHKGMPGGRNLYRIQLNDYTKVTCLSCELNPERCQ 417 Query: 457 YYSVSLSKEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLD 516 YYS S S +AKYYQL C GPGLPLYTLH S+ KELRVLEDNSALDKMLQDVQMPSKKLD Sbjct: 418 YYSASFSNKAKYYQLRCFGPGLPLYTLHSSSSDKELRVLEDNSALDKMLQDVQMPSKKLD 477 Query: 517 FIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIV 576 I L+ T+FWYQMILPPHFDKSKKYPLLI+VYAGPCSQK D FRL+WATYLASTENIIV Sbjct: 478 VINLHGTKFWYQMILPPHFDKSKKYPLLIEVYAGPCSQKVDTVFRLSWATYLASTENIIV 537 Query: 577 ASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYV 636 ASFDGRGSGYQGDKIMHAIN+RLGT EVEDQIEA RQF KMGFVD KR+AIWGWSYGGYV Sbjct: 538 ASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEATRQFSKMGFVDDKRIAIWGWSYGGYV 597 Query: 637 TSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENF 696 TSMVLG+GSGVFKCGIAVAPVS+WEYYDSVYTERYMGLPTPEDNLD+YRNSTVMSRAENF Sbjct: 598 TSMVLGAGSGVFKCGIAVAPVSKWEYYDSVYTERYMGLPTPEDNLDYYRNSTVMSRAENF 657 Query: 697 KQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHM 756 KQVEYLLIHGTADDNVHFQQSAQ+SKALVDAGVDFQ MWYTDEDHGIAS+ AHQHIY+HM Sbjct: 658 KQVEYLLIHGTADDNVHFQQSAQLSKALVDAGVDFQTMWYTDEDHGIASNMAHQHIYTHM 717 Query: 757 SHFLQQCFSL 766 SHFL+QCFSL Sbjct: 718 SHFLKQCFSL 727 >1Z68-A nrPDB Length = 719 Score = 872 bits (2252), Expect = 0.0, Method: Composition-based stats. Identities = 393/729 (53%), Positives = 528/729 (72%), Gaps = 13/729 (1%) Query: 39 RTYTLADYLKNTFRVKSYSLRWVSDSEYLYKQ-ENNILLFNAEHGNSSIFLENSTFEIFG 97 R TL D L TF K++ W+S EYL++ +NNI+L+N E G S L N T + Sbjct: 2 RALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKS-- 59 Query: 98 DSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQ 157 + S+Y +SPDR FV LE +Y K WR+SYTA+Y IYDL+ + + ++P Q++ WS Sbjct: 60 VNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSP 119 Query: 158 EGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSALWWSPN 217 G KLAYV++N+IY+K P P +IT G+EN IFNGI DWVYEEE+ ALWWSPN Sbjct: 120 VGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPN 179 Query: 218 GTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSST 277 G FLAYA+FNDT +P+I YS+Y DE QYP+T+ IPYPKAGA NP V+ FI++T + Sbjct: 180 GKFLAYAEFNDTDIPVIAYSYYGDE--QYPRTINIPYPKAGAKNPVVRIFIIDT---TYP 234 Query: 278 TTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTTLVWNC 337 P ++ PA + + D+Y + WV+++R+ LQWL+R+QN SV++ICD+ + W+C Sbjct: 235 AYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDC 294 Query: 338 PTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVCTF 397 P TQEHIE S TGW G F + P F+ D S+YKI SDKDGYKHI + KD + Sbjct: 295 PKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHI-HYIKDTVENAIQ-- 351 Query: 398 ITKGAWEVISIEALTSDYLYYISNEYKEMPGGRNLYKIQLTDHTN-KKCLSCDLNPERCQ 456 IT G WE I+I +T D L+Y SNE++E PG RN+Y+I + + KKC++C L ERCQ Sbjct: 352 ITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQ 411 Query: 457 YYSVSLSKEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLD 516 YY+ S S AKYY L C GPG+P+ TLH +E+++LE+N L+ L+++Q+P +++ Sbjct: 412 YYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIK 471 Query: 517 FIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIV 576 + ++E WY+MILPP FD+SKKYPLLI VY GPCSQ + F +NW +YLAS E +++ Sbjct: 472 KLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVI 531 Query: 577 ASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYV 636 A DGRG+ +QGDK+++A+ ++LG EVEDQI A R+F++MGF+D KR+AIWGWSYGGYV Sbjct: 532 ALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYV 591 Query: 637 TSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENF 696 +S+ L SG+G+FKCGIAVAPVS WEYY SVYTER+MGLPT +DNL+HY+NSTVM+RAE F Sbjct: 592 SSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYF 651 Query: 697 KQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHM 756 + V+YLLIHGTADDNVHFQ SAQI+KALV+A VDFQAMWY+D++HG++ + H+Y+HM Sbjct: 652 RNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSG-LSTNHLYTHM 710 Query: 757 SHFLQQCFS 765 +HFL+QCFS Sbjct: 711 THFLKQCFS 719 >4WJL-A nrPDB Length = 719 Score = 804 bits (2075), Expect = 0.0, Method: Composition-based stats. Identities = 262/740 (35%), Positives = 426/740 (57%), Gaps = 33/740 (4%) Query: 37 SRRTYTLADYLKNTFRVKSYSLRWVSDSEYLYKQEN-NILLFNAEHGNSSIFLENSTFEI 95 S +L D + F + RW++D++ +YK EN +++ N E +++ LEN+TF Sbjct: 1 SETRLSLEDLFRKDFVLHDPEARWINDTDVVYKSENGHVIKLNIETNATTLLLENTTFVT 60 Query: 96 FGDSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQL--ITEEKIPNNT-QW 152 F S +SVSPD +VLL Y+ + + +SYTASY IY+++ R++ + ++ ++ Q+ Sbjct: 61 F--KASRHSVSPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTREVWELNPPEVEDSVLQY 118 Query: 153 ITWSQEGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSAL 212 W +G +L Y+++N+IY + + S R+TS+GKE +IFNGI DW+YEEE+ ++ A Sbjct: 119 AAWGVQGQQLIYIFENNIYYQPDIKSSSLRLTSSGKEEIIFNGIADWLYEEELLHSHIAH 178 Query: 213 WWSPNGTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTD 272 WWSP+G LA+ ND+ VP + ++ YPK PYPKAG +NPT+K ++VN Sbjct: 179 WWSPDGERLAFLMINDSLVPTMVIPRFTG--ALYPKGKQYPYPKAGQMNPTIKLYVVNLY 236 Query: 273 SLSSTTTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTT 332 + T +++ P S + ++Y+ V WVS + ++WL R QN S++ +C+ T Sbjct: 237 GPTHT-----LELMPPDSFKSREYYITMVKWVSNTKTVVRWLNRAQNISILTVCE----T 287 Query: 333 LVWNCPTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDG----YKHICQFQKD 388 C + E ++ W + + EP F+ DGS F+ V K G + HI F Sbjct: 288 TTGAC---SKKYEMTSDTWLSQ-QNEEPVFSRDGSKFFMTVPVKQGGRGEFHHIAMFLIQ 343 Query: 389 RKPEQVC-TFITKGAWEVISIEAL--TSDYLYYISNEYKEMPGGRNLYKIQLTDHTNKKC 445 K EQ+ +T G WEVI I A T+ +Y++S E P GR LY N++C Sbjct: 344 SKSEQITVRHLTSGNWEVIKILAYDETTQKIYFLSTE--SSPRGRQLYSASTEGLLNRQC 401 Query: 446 LSCDLNPERCQYYSVSLSKEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKML 505 +SC+ E+C Y+ S S +++ L C GP +P+ +LH + + + +LE NS L + + Sbjct: 402 ISCNFMKEQCTYFDASFSPMNQHFLLFCEGPRVPVVSLHSTDNPAKYFILESNSMLKEAI 461 Query: 506 QDVQMPSKKLDFIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWA 565 ++ ++ + +++ Q+ LP F +Y LL+ + P Q F ++W Sbjct: 462 LKKKIGKPEIKILHIDDYELPLQLSLPKDFMDRNQYALLLIMDEEPGGQLVTDKFHIDWD 521 Query: 566 TYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRV 625 + L +N+IVA FDGRGSG+QG KI+ I++RLG++EV+DQI A + LK+ ++DSKR+ Sbjct: 522 SVLIDMDNVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRL 581 Query: 626 AIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYR 685 +I+G YGGY+ SM+L S +FKCG VAP++ + Y S ++ERY+G+P+ E++ Y+ Sbjct: 582 SIFGKGYGGYIASMILKSDEKLFKCGSVVAPITDLKLYASAFSERYLGMPSKEEST--YQ 639 Query: 686 NSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIAS 745 ++V+ K+ L+IHGTAD VHFQ SA++ K L+ AGV++ Y DE H ++ Sbjct: 640 AASVLHNVHGLKEENILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGHNVSE 699 Query: 746 STAHQHIYSHMSHFLQQCFS 765 + H+YS + F C Sbjct: 700 K-SKYHLYSTILKFFSDCLK 718 >1XFD-A nrPDB Length = 723 Score = 784 bits (2023), Expect = 0.0, Method: Composition-based stats. Identities = 245/745 (32%), Positives = 404/745 (54%), Gaps = 39/745 (5%) Query: 38 RRTYTLADYLKNTFRVKSYSLRWVSDSEYLYK-QENNILLFNAEHGNSSIFLENSTFEIF 96 ++ T+ D F++ +W+SD+E++Y+ Q+ + L+N E S++ +E E Sbjct: 2 KKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEGKKIESL 61 Query: 97 GDSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDL---NKRQLITEEKIPNNTQWI 153 Y +SPDR + L YN ++HSYT Y + + + + L E Q+ Sbjct: 62 --RAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAKLQYA 119 Query: 154 TWSQEGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSALW 213 W +G +L ++++N+IY + R+ STGKE VI+NG++DW+YEEEI + A W Sbjct: 120 GWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHIAHW 179 Query: 214 WSPNGTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDS 273 WSP+GT LAYA ND+ VP++E Y+ YP YPKAG+ NP++ ++ + Sbjct: 180 WSPDGTRLAYAAINDSRVPIMELPTYTGSI--YPTVKPYHYPKAGSENPSISLHVIGLNG 237 Query: 274 LSSTTTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTTL 333 T +++ P ++Y+ V W + ++++ WL R QN S++ +CD TT Sbjct: 238 P-----THDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCD--ATTG 290 Query: 334 VWNCPTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDG----YKHICQF--QK 387 V T++H E + W R + EP F+ DG F+ I + G + HI Q Sbjct: 291 V----CTKKH-EDESEAWLHR-QNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQP 344 Query: 388 DRKPEQVCTFITKGAWEVISIEAL--TSDYLYYISNEYKEMPGGRNLYKIQLTDHTNKKC 445 + + + + IT G W+V I A + +Y++S E ++P R LY + N++C Sbjct: 345 NSSNDNIQS-ITSGDWDVTKILAYDEKGNKIYFLSTE--DLPRRRQLYSANTVGNFNRQC 401 Query: 446 LSCDLNPERCQYYSVSLSKEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKML 505 LSCDL E C Y+S S S ++ L C GPG+P+ T+H +TD+K++ LE N + K + Sbjct: 402 LSCDLV-ENCTYFSASFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAI 460 Query: 506 QDVQMPSKKLDFIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWA 565 D QMP + I +++ Q++ P F + YPLL+ V P SQ F ++W Sbjct: 461 NDRQMPKVEYRDIEIDDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWE 520 Query: 566 TYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRV 625 T + S+ +V DGRGSG+QG K++H + +RLG LE +DQ+EA R LK ++D RV Sbjct: 521 TVMVSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRV 580 Query: 626 AIWGWSYGGYVTSMVLGSGSG----VFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNL 681 A++G YGGY+++ +L + F CG A++P++ ++ Y S ++ERY+GL ++ Sbjct: 581 AVFGKDYGGYLSTYILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRA 640 Query: 682 DHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDH 741 Y + V R ++ ++L+IH TAD+ +HFQ +A++ L+ ++ Y DE H Sbjct: 641 --YEMTKVAHRVSALEEQQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESH 698 Query: 742 GIASSTAHQHIYSHMSHFLQQCFSL 766 SS+ QH+Y + +F +CF + Sbjct: 699 YFTSSSLKQHLYRSIINFFVECFRI 723 >5OLJ-A nrPDB Length = 723 Score = 687 bits (1772), Expect = 0.0, Method: Composition-based stats. Identities = 231/775 (29%), Positives = 361/775 (46%), Gaps = 63/775 (8%) Query: 1 MKTPWKVLLGLLGVAALVTIITVPVVLLNKDEAAADSRRTYTLADYLKNTF--RVKSYSL 58 MK P V++ LLG+ + + A + L + F R + Sbjct: 1 MKRP--VIILLLGIVTMCAM-------------AQTGDKPVDLKEITSGMFYARSAGRGI 45 Query: 59 RWVSDSEY---LYKQENNILLFNAEHGNS--SIFLENSTFEIFGDSISDYSVSPDRLFVL 113 R + D E+ + ++ I+ +N G + ++F E I +Y VS +L Sbjct: 46 RSMPDGEHYTEMNRERTAIVRYNYASGKAVDTLFSIERARECPFKQIQNYEVSSTGHHIL 105 Query: 114 LEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQEGHKLAYVWKNDIYVK 173 L + +RHSY A+ YD+ + + + T+S +G +A+V N+I++K Sbjct: 106 LFTDMESIYRHSYRAAVYDYDVRRNLVKPLSEHVGKVMIPTFSPDGRMVAFVRDNNIFIK 165 Query: 174 IEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSALWWSPNGTFLAYAQFNDTGVPL 233 ++T+ G+ N + NG DWVYEEE FG + + WS + FLA+ + +++ VP Sbjct: 166 KFDFDTEVQVTTDGQINSVLNGATDWVYEEE-FGVTNLMSWSADNAFLAFVRSDESAVPE 224 Query: 234 IEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSSTTTTIPMQITAPASVTT 293 Y D+ YP+ YPKAG N TV + N ++ + ++P+ Sbjct: 225 YRMPMYEDK--LYPEDYTYKYPKAGEKNSTVSLHLYNVADRNTKSVSLPID--------- 273 Query: 294 GDHYLCDVAWVSE-DRISLQWLRRIQNYSVMAICDYDKTTLVWNCPTTQEHIETSATGWC 352 D Y+ +A+ D +++ L R+QN M +LV + + W Sbjct: 274 ADGYIPRIAFTDNADELAVMTLNRLQNDFKMYYVH--PKSLVPKLILQDMNKRYVDSDWI 331 Query: 353 GRFRPAEPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVCTFITKGAWEVISIEA-L 411 + FT+ G + VS+KDG+ HI + + IT G W+V + Sbjct: 332 QALK-----FTAGGG--FAYVSEKDGFAHIYLYDNKGVMHRR---ITSGNWDVTKLYGVD 381 Query: 412 TSDYLYYISNEYKEMPGGRNLYKIQLTDHTNKKCLSCDLNPERCQYYSVSLSKEAKYYQL 471 S ++Y S E E P R +Y I K L+ N S YY Sbjct: 382 ASGTVFYQSAE--ESPIRRAVYAIDAKGRKTKLSLNVGTN-------DALFSGNYAYYIN 432 Query: 472 GCRGPGLP-LYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDFIVL-NETRFWYQM 529 P + ++ RS KELR LEDN AL + L+ + K+ I + + Sbjct: 433 TYSSAATPTVVSVFRSKGAKELRTLEDNVALRERLKAYRYNPKEFTIIKTQSALELNAWI 492 Query: 530 ILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGD 589 + P FD S+ YP+L+ Y+GP SQ+ + +W YLAS + +VA DGRG+G +G+ Sbjct: 493 VKPIDFDPSRHYPVLMVQYSGPNSQQVLDRYSFDWEHYLAS-KGYVVACVDGRGTGARGE 551 Query: 590 KIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFK 649 + +LG E +DQI AA ++ +VD+ R+ IWGWSYGGY T M L G+G FK Sbjct: 552 EWRKCTYMQLGVFESDDQIAAATAIGQLPYVDAARIGIWGWSYGGYTTLMSLCRGNGTFK 611 Query: 650 CGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTAD 709 GIAVAPV+ W +YDSVYTER+M TP++N Y+ S+ + A Q L++ G+AD Sbjct: 612 AGIAVAPVADWRFYDSVYTERFM--RTPKENASGYKMSSALDVASQL-QGNLLIVSGSAD 668 Query: 710 DNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFLQQCF 764 DNVH Q + ++ALV A + F Y D++H I H+Y+ + FL Sbjct: 669 DNVHLQNTMLFTEALVQANIPFDMAIYMDKNHSIYGGNTRYHLYTRKAKFLFDNL 723 >5YP1-A nrPDB Length = 745 Score = 616 bits (1587), Expect = e-176, Method: Composition-based stats. Identities = 171/693 (24%), Positives = 288/693 (41%), Gaps = 68/693 (9%) Query: 90 NSTFEIFGDSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNN 149 I DY SPD +L YDL K K+ N Sbjct: 103 ERQRIAALSGIVDYQWSPDGKALLFPLG----------GELYFYDLTKSGRDAVRKLTNG 152 Query: 150 TQWIT---WSQEGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIF 206 + T S +G ++++ +++ ++T G + I NG+ ++V +EE+ Sbjct: 153 GGFATDPKISPKGGFVSFIRDRNLWAIDLASGKEVQLTRDGSDT-IGNGVAEFVADEEM- 210 Query: 207 GAYSALWWSPNGTFLAYAQFNDTGVPLIE-YSFYSDESLQYPKTVWIPYPKAGAVNPTVK 265 ++ WW+P+ +A+A+ ++T VP+ + Y Y D + + V YP AG N V+ Sbjct: 211 DRHTGYWWAPDDAAIAFARIDETPVPVQKRYEVYPDRT----EVVEQRYPAAGDHNVRVQ 266 Query: 266 FFIVNTDSLSSTTTTIPMQITAPASVTTG---DHYLCDVAWVSEDRISLQWLRRIQNYSV 322 ++ P P + G D YL V W R++ Q R Q Sbjct: 267 LGVI-----------APKTGARPRWIDLGKDPDIYLARVDWRDPQRLTFQRQSRDQKK-- 313 Query: 323 MAICDYDKTTLVWNCPTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGYKHI 382 + +TTL T + + ++T W + F DG + S++ G++H+ Sbjct: 314 ---IELIETTLTNG--TQRTLVTETSTTWVPLHN--DLRFLKDGRFLWS--SERSGFEHL 364 Query: 383 CQFQKDRKPEQVCTFITKGAWEVISIEALTSDYLYYISNEYKEMPGGRNLYKIQLTDHTN 442 +D T +T+G W V S+ A+ + ++ ++Y + L+ Sbjct: 365 YVASEDGS---TLTALTQGEWVVDSLLAIDEAAGLAYVSGTRDGATEAHVYAVPLSGGEP 421 Query: 443 KKCLSCDLNPERCQYYSVSLSKEAKYYQLG-CRGPGLPLYTLHRSTDQKELRVLEDNSAL 501 ++ + ++ + ++ A + LP L ++ D +L L N Sbjct: 422 RRLT------QAPGMHAATFARNASVFVDSWSSDTTLPQIELFKA-DGTKLATLLVNDVS 474 Query: 502 DKM-----LQDVQMPSKKLDFIVLNET-RFWYQMILPPHFDKSKKYPLLIDVYAGPCSQK 555 D + P+ + T Y +I P FD K+YP+++ VY GP +Q Sbjct: 475 DATHPYAKYRAAHQPTAYGTLTAADGTTPLHYSLIKPAGFDPKKQYPVVVFVYGGPAAQT 534 Query: 556 ADAAFRLNWATYLAS---TENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAAR 612 A+ ++ + +V + D RG+ +G A+ + GT+EV+DQ+ Sbjct: 535 VTRAWPGRSDSFFNQYLAQQGYVVFTLDNRGTPRRGAAFGGALYGKQGTVEVDDQLRGIE 594 Query: 613 QFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYM 672 FVD R+ ++GWS GGY+T M+L + CG+A APV+ W YD+ YTERYM Sbjct: 595 WLKSQAFVDPARIGVYGWSNGGYMTLMLLAKHDEAYACGVAGAPVTDWALYDTHYTERYM 654 Query: 673 GLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQ 732 L P+ N YR ++V + + + LLIHG ADDNV F S ++ L G F+ Sbjct: 655 DL--PKANEAGYREASVFTHVDGIGAGKLLLIHGMADDNVLFTNSTKLMSELQKRGTPFE 712 Query: 733 AMWYTDEDHGIASSTAHQHIYSHMSHFLQQCFS 765 M Y HG+ S H Y F +C Sbjct: 713 LMTYPGAKHGLRGSDL-LHRYRLTEDFFARCLK 744 >2ECF-A nrPDB Length = 741 Score = 612 bits (1579), Expect = e-175, Method: Composition-based stats. Identities = 183/697 (26%), Positives = 290/697 (41%), Gaps = 78/697 (11%) Query: 90 NSTFEIFGDSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNK------RQLITE 143 I DY SPD +L +YDL + RQL Sbjct: 101 ERQRIAAMTGIVDYQWSPDAQRLLFPLG----------GELYLYDLKQEGKAAVRQLTHG 150 Query: 144 EKIPNNTQWITWSQEGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEE 203 E + + S +G ++++ +++V ++T+ G I NGI ++V +E Sbjct: 151 EGFATDAKL---SPKGGFVSFIRGRNLWVIDLASGRQMQLTADGS-TTIGNGIAEFVADE 206 Query: 204 EIFGAYSALWWSPNGTFLAYAQFNDTGVPLIE-YSFYSDESLQYPKTVWIPYPKAGAVNP 262 E+ ++ WW+P+ + +AYA+ +++ VP+ + Y Y+D + + YP AG N Sbjct: 207 EM-DRHTGYWWAPDDSAIAYARIDESPVPVQKRYEVYADRT----DVIEQRYPAAGDANV 261 Query: 263 TVKFFIVNTDSLSSTTTTIPMQITAPASVTTG---DHYLCDVAWVSEDRISLQWLRRIQN 319 VK +++ P + + G D YL V W +S Q R Q Sbjct: 262 QVKLGVIS-----------PAEQAQTQWIDLGKEQDIYLARVNWRDPQHLSFQRQSRDQK 310 Query: 320 YSVMAICDYDKTTLVWNCPTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGY 379 D + TL N H ++ W F DGS + S++ G+ Sbjct: 311 K-----LDLVEVTLASNQQRVLAH--ETSPTWVPLHNSL--RFLDDGSILWS--SERTGF 359 Query: 380 KHICQFQKDRKPEQVCTFITKGAWEVISIEALTSDYLYYISNEYKEMPGGRNLYKIQLTD 439 +H+ + K +T G W V + A+ E +Y + L Sbjct: 360 QHLYRIDSKGK----AAALTHGNWSVDELLAVDEKAGLAYFRAGIESARESQIYAVPLQG 415 Query: 440 HTNKKCLSCDLNPERCQYYSVSLSKEAKYYQLG-CRGPGLPLYTLHRSTDQKELRVLEDN 498 ++ +S S ++ A Y P L R+ +K ++E++ Sbjct: 416 GQPQRLSKA------PGMHSASFARNASVYVDSWSNNSTPPQIELFRANGEKIATLVEND 469 Query: 499 SALDK----MLQDVQMPSKKLDFIVLNE--TRFWYQMILPPHFDKSKKYPLLIDVYAGPC 552 A K ++ Q P + + + T Y +I P FD +K+YP+ + VY GP Sbjct: 470 LADPKHPYARYREAQRP-VEFGTLTAADGKTPLNYSVIKPAGFDPAKRYPVAVYVYGGPA 528 Query: 553 SQKADAAF----RLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQI 608 SQ ++ + YLA + +V S D RG+ +G A+ + GT+EV DQ+ Sbjct: 529 SQTVTDSWPGRGDHLFNQYLAQ-QGYVVFSLDNRGTPRRGRDFGGALYGKQGTVEVADQL 587 Query: 609 EAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYT 668 + +VD R+ + GWS GGY+T M+L S + CG+A APV+ W YDS YT Sbjct: 588 RGVAWLKQQPWVDPARIGVQGWSNGGYMTLMLLAKASDSYACGVAGAPVTDWGLYDSHYT 647 Query: 669 ERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAG 728 ERYM L P N YR + V++ E + LLIHG ADDNV F S + AL G Sbjct: 648 ERYMDL--PARNDAGYREARVLTHIEGLRS-PLLLIHGMADDNVLFTNSTSLMSALQKRG 704 Query: 729 VDFQAMWYTDEDHGIASSTAHQHIYSHMSHFLQQCFS 765 F+ M Y HG++ + A H Y FL +C Sbjct: 705 QPFELMTYPGAKHGLSGADA-LHRYRVAEAFLGRCLK 740 >4Q1V-A nrPDB Length = 710 Score = 572 bits (1475), Expect = e-163, Method: Composition-based stats. Identities = 168/762 (22%), Positives = 312/762 (40%), Gaps = 92/762 (12%) Query: 39 RTYTLADYLKNT----FRVKSYSLRWVSDSEYLYKQENNILLFNAEHGNSSIFL----EN 90 + TL + + + Y L+W D E + + + + G ++ + N Sbjct: 5 KKPTLEELIPGGESYLYAENLYGLQWWGD-ECIKPGVDTLYSIQPKTGKETMVITREQIN 63 Query: 91 STFEIFGDSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNT 150 E + S V + Q + + +Y+ Q+++ K + Sbjct: 64 KVLEENKAGKLSHLYS-----VRFPWTDKAQMLFTIAGKFIVYNFKNNQVVSTFKPKDGA 118 Query: 151 QWITWSQEGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYS 210 + +AY N++YV + + + E ++ V+ E FG Sbjct: 119 NNEDYCAASGNVAYTIDNNLYV-------NEKAVTNEPEGIV---CGQTVHRNE-FGINK 167 Query: 211 ALWWSPNGTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVN 270 +WSP G LA+ + +++ V D + + + + YP AG + VK I N Sbjct: 168 GTFWSPKGNLLAFYRMDESMVTQY---PLVDITARVGEVNNVRYPMAGMTSHQVKVGIYN 224 Query: 271 TDSLSSTTTTIPMQITAPASVTTGDHYLCDVAWVSEDR-ISLQWLRRIQNYSVMAICDYD 329 +T +I + P D Y +++W +++ + L + R QN++ +C Y+ Sbjct: 225 ----PATGKSIYLNAGDPT-----DRYFTNISWAPDEKSLYLIEVNRDQNHAK--LCQYN 273 Query: 330 -KTTLVWNCPTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGYKHICQFQKD 388 +T + H + F P +P + + S +DGY H+ F+ + Sbjct: 274 AETGEPMGVLYEEMHPKYVEPQNPIVFLPWDP-------TKFIYQSQRDGYNHLYLFETN 326 Query: 389 RKPEQVCTFITKGAWEVISIEALTSDYLYYISNEYKEMPGGRNLYKIQLTDHTNKK-CLS 447 + T+ + Y+ + + K++ G L L +T +K + Sbjct: 327 AANMKGETYNSANGGS------------YFQAGKVKQLTKGNWLVSEILGFNTKRKEVIF 374 Query: 448 CDLNPERCQYYSVSLS-----------KEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLE 496 + R +++V++S KE+++ G L + + DQ + L Sbjct: 375 TAVEGLRSGHFAVNVSNGKISQPFENCKESEHSG-TLSASGTYLIDRYSTKDQPRVINLV 433 Query: 497 DNSALDKMLQ---------DVQMPSKKLDFIVLNE--TRFWYQMILPPHFDKSKKYPLLI 545 D + QMPS + I + T Y+++ P +FD +KKYP+++ Sbjct: 434 DTKNFKETANLLTAENPYDGYQMPSIETGTIKAADGTTDLHYRLMKPANFDPAKKYPVIV 493 Query: 546 DVYAGPCSQKADAAFR---LNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTL 602 VY GP +Q ++ W TY+AS + I+ + D RGS +G +A +RLG Sbjct: 494 YVYGGPHAQCVTGGWQNGARGWDTYMAS-KGYIMFTIDNRGSSNRGLTFENATFRRLGIE 552 Query: 603 EVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEY 662 E +DQ++ + +VDS+R+ + GWS+GG++T+ ++ +FK G+A PV W Y Sbjct: 553 EGKDQVKGVEFLKSLPYVDSERIGVHGWSFGGHMTTALMLRYPEIFKVGVAGGPVIDWGY 612 Query: 663 YDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISK 722 Y+ +Y ERYM TPE N + Y+ + + A+ K L+IH DD Q + K Sbjct: 613 YEIMYGERYMD--TPESNPEGYKECNLKNLADQLK-GHLLIIHDDHDDTCVPQHTLSFMK 669 Query: 723 ALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFLQQCF 764 A VDA Y H +A H++ ++ + +Q Sbjct: 670 ACVDARTYPDLFIYPCHKHNVAGRD-RVHLHEKITRYFEQNL 710 >2EEP-A nrPDB Length = 706 Score = 562 bits (1449), Expect = e-160, Method: Composition-based stats. Identities = 161/656 (24%), Positives = 279/656 (42%), Gaps = 69/656 (10%) Query: 128 ASYSIYDLNKRQLITEEKIPNNTQWITWSQEGHKLAYVWKNDIYVKIEPHLPSHR----- 182 +D+ R++ T + +S G ++AYV +++Y+ L Sbjct: 101 GGLVGFDMLARKVTYLFDTNEETASLDFSPVGDRVAYVRNHNLYIARGGKLGEGMSRAIA 160 Query: 183 ITSTGKENVIFNGINDWVYEEEIFGAYSALWWSPNGTFLAYAQFNDTGV---PLIEYSFY 239 +T G E +++ V++ E FG +WSP G+ LA+ + + + V P+++Y Sbjct: 161 VTIDGTETLVY---GQAVHQRE-FGIEKGTFWSPKGSCLAFYRMDQSMVKPTPIVDYHPL 216 Query: 240 SDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSSTTTTIPMQITAPASVTTGDHYLC 299 ES + YP AG + V I + +T T+ +Q P + +L Sbjct: 217 EAES------KPLYYPMAGTPSHHVTVGIYHL----ATGKTVYLQTGEPK-----EKFLT 261 Query: 300 DVAWVSEDRI-SLQWLRRIQNYSVMAICDYDKTTLVW--NCPTTQEHIETSATGWCGRFR 356 +++W ++ I + + R QN + D + V T + ++E Sbjct: 262 NLSWSPDENILYVAEVNRAQNECKVNAYDAETGRFVRTLFVETDKHYVE----------- 310 Query: 357 PAEPHFTSDGSSFYKI-VSDKDGYKHICQFQKDRKPEQVCTFITKGAWEVISIEAL--TS 413 P P GS+ I S +DG+ H+ + + + +TKG WEV + Sbjct: 311 PLHPLTFLPGSNNQFIWQSRRDGWNHLYLYDTTGR---LIRQVTKGEWEVTNFAGFDPKG 367 Query: 414 DYLYYISNEYKEMPGGRNLYKIQLTDHTNKKCLSCDLNPERCQYYSVSLSKEAKYYQLGC 473 LY+ S E P R+ Y I + K DL PE + + LS + Sbjct: 368 TRLYFESTEA--SPLERHFYCIDIKGGKTK-----DLTPESGMHRT-QLSPDGSAIIDIF 419 Query: 474 RGPGLPLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDFIVLNE--TRFWYQMIL 531 + P +P + + +LE + MP + I+ + T +Y++ + Sbjct: 420 QSPTVPRKVTVTNIGKGSHTLLEAKNPD----TGYAMPEIRTGTIMAADGQTPLYYKLTM 475 Query: 532 PPHFDKSKKYPLLIDVYAGPCSQKADAAFRLN---WATYLASTENIIVASFDGRGSGYQG 588 P HFD +KKYP+++ VY GP +Q +R + W Y+A + V + D RGS +G Sbjct: 476 PLHFDPAKKYPVIVYVYGGPHAQLVTKTWRSSVGGWDIYMAQ-KGYAVFTVDSRGSANRG 534 Query: 589 DKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVF 648 I++RLG E+ DQ+ +VD+ R+ + GWSYGG++T+ ++ + VF Sbjct: 535 AAFEQVIHRRLGQTEMADQMCGVDFLKSQSWVDADRIGVHGWSYGGFMTTNLMLTHGDVF 594 Query: 649 KCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTA 708 K G+A PV W Y+ +Y ERY P++N + Y + ++ RA + K +LIHG Sbjct: 595 KVGVAGGPVIDWNRYEIMYGERY--FDAPQENPEGYDAANLLKRAGDLK-GRLMLIHGAI 651 Query: 709 DDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFLQQCF 764 D V +Q S A V A Y +H + H+Y ++ + Sbjct: 652 DPVVVWQHSLLFLDACVKARTYPDYYVYPSHEHNVMGPD-RVHLYETITRYFTDHL 706 >6EOT-A nrPDB Length = 898 Score = 501 bits (1290), Expect = e-142, Method: Composition-based stats. Identities = 185/712 (25%), Positives = 286/712 (40%), Gaps = 113/712 (15%) Query: 137 KRQLITEEKIPNNTQWITWSQEGHKLAYVWKNDIYVKIEPHLP-SHRITSTGKENVIFNG 195 + + P + WI + +W ++I + E L H + +E+ G Sbjct: 212 PNIRMDPKLCPADPDWIAFIHSND----IWISNIVTREERRLTYVHNELANMEEDARSAG 267 Query: 196 INDWVYEEEIFGAYSALWW------SPNGTFLAYAQFNDTGVPLIEYSFYSDESLQYPKT 249 + +V +EE F YS WW +P+G + + + +E + L+ + Sbjct: 268 VATFVLQEE-FDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRA 326 Query: 250 VWIPYPKAGAVNPTVKFFI--VNTDSLSSTTTTIPMQITAPASVT-TGDHYLCDVAWVSE 306 YPK G NP V F + + D+ I ++ P + G Y+ W E Sbjct: 327 DSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPE 386 Query: 307 DRIS-----------------------------LQWLRRIQNY--SVMAICDYDKTTLVW 335 + + ++ R I++ SV + Y++TT +W Sbjct: 387 GKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIW 446 Query: 336 ---------NCPTTQEHIETSATGWCGR-FRPAEPHFTSDGSSFYKIVSDKDGYKHICQF 385 + +E IE C FR + S YK S G F Sbjct: 447 INIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSG--GLPAPSDF 504 Query: 386 QKDRKPEQVCTFITKGAWEVI-----SIEALTSDYLYYISNEYKEMPGGRNLYKIQLT-- 438 + K E IT G WEV+ +I+ L Y K+ P +LY + Sbjct: 505 KCPIKEE---IAITSGEWEVLGRHGSNIQVDEVRRLVYFEGT-KDSPLEHHLYVVSYVNP 560 Query: 439 ---------DHTNKKCLSCDLNPERCQYYSVSLSKEAKYYQLGCRGPGLPLYTLHRSTDQ 489 +++ C+S + C ++ +SK + C + LY L D Sbjct: 561 GEVTRLTDRGYSHSCCIS-----QHCDFF---ISKYSNQKNPHC----VSLYKLSSPEDD 608 Query: 490 KELRVLED-NSALDKM--LQDVQMPSKKLDFIVLNETRF-WYQMILPPH-FDKSKKYPLL 544 + E + LD L D P F + T F Y M+ PH KKYP + Sbjct: 609 PTCKTKEFWATILDSAGPLPDYTPPEI---FSFESTTGFTLYGMLYKPHDLQPGKKYPTV 665 Query: 545 IDVYAGPCSQ------KADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKR 598 + +Y GP Q K FRLN LAS +V D RGS ++G K A + Sbjct: 666 LFIYGGPQVQLVNNRFKGVKYFRLN---TLASL-GYVVVVIDNRGSCHRGLKFEGAFKYK 721 Query: 599 LGTLEVEDQIEAARQFL-KMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPV 657 +G +E++DQ+E + + F+D RV I GWSYGGY++ M L S +F+ IA APV Sbjct: 722 MGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPV 781 Query: 658 SRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENF--KQVEYLLIHGTADDNVHFQ 715 + W +YD+ YTERYMG P+ N Y +V +AE F + LL+HG D+NVHF Sbjct: 782 TLWIFYDTGYTERYMG--HPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFA 839 Query: 716 QSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFLQQCFSLR 767 ++ + LV AG + Y E H I + +H H+ H+LQ+ R Sbjct: 840 HTSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSR 891 >6EOR-A nrPDB Length = 869 Score = 396 bits (1018), Expect = e-110, Method: Composition-based stats. Identities = 168/752 (22%), Positives = 281/752 (37%), Gaps = 88/752 (11%) Query: 86 IFLENSTFEIFGDSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEK 145 + E +FG + D+ S LF+ N + R + + + ++ T + Sbjct: 127 LLRERKRLGVFGITSYDFH-SESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKT--Q 183 Query: 146 IPNNTQWITWSQEG-HKLAYVWKNDIYVKIEPHLPSHRIT------STGKENVIFNGIND 198 +++ +D++V R+T S ++ G+ Sbjct: 184 CSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVAT 243 Query: 199 WVYEEEIFGAYSALWWSP-------NGTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVW 251 +V +EE F ++ WW P G + + +E +L+ KT Sbjct: 244 FVIQEE-FDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDS 302 Query: 252 IPYPKAGAVNPTVKFFI--VNTDSLSSTTTTIPMQITAPAS-VTTGDHYLCDVAWVSEDR 308 YP+ G+ NP + + TDS +T ++ P S + Y+ W + + Sbjct: 303 YRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGK 362 Query: 309 ISL-QWLRRIQNYSVMAICDYDKTTLVWNCPTTQEH----------------IETSATGW 351 + +L R Q + + + + + ++ E W Sbjct: 363 YAWAMFLDRPQQW--LQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVW 420 Query: 352 CGRFRPAEPHFTSDGSS---FYKIVSDKDGYKHICQ----------------------FQ 386 P S+G F + K G+ H+ + F+ Sbjct: 421 INVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFK 480 Query: 387 KDRKPEQVCTFITKGAWEVI-----SIEALTSDYLYYISNEYKEMPGGRNLYKIQLTDHT 441 K E +T G WEV+ I L Y K+ P +LY + Sbjct: 481 CPIKEE---IALTSGEWEVLARHGSKIWVNEETKLVYFQGT-KDTPLEHHLYVVSYEAAG 536 Query: 442 NKKCLSCDLNPERCQYYSVSLSKEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSAL 501 L+ C S + +Y P + +Y L D + +++ Sbjct: 537 EIVRLTTPGFSHSCSM-SQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASM 595 Query: 502 DKM---LQDVQMPSKKLDFIVLNETRFWYQMILPPH-FDKSKKYPLLIDVYAGPCSQKAD 557 + D P F ++ R Y MI PH KK+P ++ VY GP Q + Sbjct: 596 MEAASCPPDYVPPEI-FHFHTRSDVRL-YGMIYKPHALQPGKKHPTVLFVYGGPQVQLVN 653 Query: 558 AAFRLNWATYLASTE--NIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFL 615 +F+ L + V DGRGS +G + A+ ++G +E+EDQ+E + Sbjct: 654 NSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVA 713 Query: 616 K-MGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGL 674 + GF+D RVAI GWSYGG+++ M L VFK IA APV+ W YD+ YTERYM + Sbjct: 714 EKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDV 773 Query: 675 PTPEDNLDHYRNSTVMSRAENF--KQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQ 732 PE+N Y +V E + L++HG D+NVHF + + L+ AG +Q Sbjct: 774 --PENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQ 831 Query: 733 AMWYTDEDHGIASSTAHQHIYSHMSHFLQQCF 764 Y +E H I + +H + HFLQ+ Sbjct: 832 LQIYPNERHSIRCPESGEHYEVTLLHFLQEYL 863 >5L8S-A nrPDB Length = 604 Score = 365 bits (936), Expect = e-101, Method: Composition-based stats. Identities = 96/489 (19%), Positives = 190/489 (38%), Gaps = 45/489 (9%) Query: 283 MQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTTLVWNCPTTQE 342 ++ + G+ ++A VSE+ S +LR N ++ + T +N E Sbjct: 141 LETGEDRLLNVGEVSTTELAAVSENEESFVYLRAFANTYIVGFVKMGEET--FNITPDPE 198 Query: 343 HIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVCTFITKGA 402 + + EP FT + + ++ D D + D ++ + Sbjct: 199 KVHVAM----------EPVFTDNETIYFATDYDSDEM---YLAKFDLTSKEFSKVLAFDG 245 Query: 403 WEVISIEALTSDYLYYISNEYKEMPGGRN-LYKIQL-TDHTNKKCLSCDLNPERCQYYSV 460 + S++ + +Y+ + G + LY+ + TD + L D+ + + Sbjct: 246 ESIQSVKWDKDNKAFYLIT----VKGVTDILYRYDVATDKVEECSLPVDIIEQ------I 295 Query: 461 SLSKEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDFIVL 520 ++K Y LG R +P + +++S++ E + L +N L +D+ P Sbjct: 296 QVAKSGNLYILG-RSATVP-HNVYQSSNGVEWKQLTNNRVLGLSPEDMVEPDIVSYTSF- 352 Query: 521 NETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFD 580 + ++ + Y + + GP S + FR + ++ I +F Sbjct: 353 -DGMEIEALLFKAKPENDNGYTIFWP-HGGPQSAER-KMFRSMFQCFINRGYTIFAPNF- 408 Query: 581 GRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMV 640 RGS G + G D I + GF D ++ + G SYGGY+ ++ Sbjct: 409 -RGSTGYGSAFTKLVELDWGEGPRLDCIAGIEWLFESGFTDRNKLFLVGGSYGGYMALLL 467 Query: 641 LGSGSGVFKCGIAV-APVSRWEYYDSV------YTERYMGLPTPEDNLDHYRNSTVMSRA 693 G S F+ + + P + + +SV ER++G PE + + + + ++ Sbjct: 468 HGRHSDYFRAVVDIFGPSDLFTFINSVPPHWKPIMERWLG--DPERDKERFIKDSPVTYL 525 Query: 694 ENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIY 753 + + L+I G D V ++S QI L + G D + + DE HG + +Y Sbjct: 526 DGMVK-PMLVIQGAKDPRVVKEESDQIVAKLKEKGRDVEYLVLEDEGHGFSKKENEIKVY 584 Query: 754 SHMSHFLQQ 762 S M FL++ Sbjct: 585 SLMLAFLEK 593 >4HXF-B nrPDB Length = 622 Score = 215 bits (548), Expect = 5e-56, Method: Composition-based stats. Identities = 68/280 (24%), Positives = 121/280 (43%), Gaps = 17/280 (6%) Query: 489 QKELRVLED-NSALDKMLQDVQMPSKKLDFIVLNETRFWYQMILPPHFDKSKKYPLLIDV 547 E R L D N + K L+ + + I L E WY + P + +K P+++ V Sbjct: 329 DGEERQLTDYNGLIFKKLKTFEPRHFRFKSIDL-ELDGWY---IKPEIKEGEKAPVIVFV 384 Query: 548 YAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQ 607 + GP K + + L +++ + + RGS + + +R G + +D Sbjct: 385 HGGP---KGMYGYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQDI 441 Query: 608 IEAARQFLKM-GFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRW----EY 662 + +FL++ D +R+ I G SYGGY+T+ L S +FK GI+ +S W + Sbjct: 442 LNGIEEFLRLEPQADRERIGITGISYGGYMTNWALTQ-SDLFKAGISENGISYWLTSYAF 500 Query: 663 YD-SVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQIS 721 D ++ ++ + P +N ++YR + + A+N K LLIH D QS Sbjct: 501 SDIGLWFDKEVIGDNPLEN-ENYRKLSPLFYAKNVK-APLLLIHSLEDYRCPLDQSLMFY 558 Query: 722 KALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFLQ 761 L D G + + HG + + +H F++ Sbjct: 559 HVLKDLGKEVYIAIFKKGAHGHSIRGSPRHRMKRYKLFME 598 >3AZQ-A nrPDB Length = 662 Score = 208 bits (530), Expect = 6e-54, Method: Composition-based stats. Identities = 62/270 (22%), Positives = 109/270 (40%), Gaps = 20/270 (7%) Query: 510 MPSKKLDFIVLNETRFWYQMILPPH-----FDKSKKYPLLIDVYAGPCSQKADAAFRLNW 564 P ++ + R + I PPH + P ++ + GP S + A L+ Sbjct: 388 YPEPQIRTFTAPDGREIHAHIYPPHSPDFTGPADELPPYVVMAHGGPTS-RVPAVLDLDV 446 Query: 565 ATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKR 624 A + ++ I VA + GS G + R G ++VED A + G D R Sbjct: 447 AYF--TSRGIGVADVNYGGSTGYGRAYRERLRGRWGVVDVEDCAAVATALAEEGTADRAR 504 Query: 625 VAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSR---W-----EYYDSVYTERYMGLPT 676 +A+ G + GG+ + L S + V+ CG + PV W ++S Y + +G + Sbjct: 505 LAVRGGAAGGWTAASSLVS-TDVYACGTVLYPVLDLLGWADGGTHDFESRYLDFLIG--S 561 Query: 677 PEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWY 736 E+ + YR+ ++RA+ + V +LL+ G D +Q + +A+ GV + + Sbjct: 562 FEEFPERYRDRAPLTRADRVR-VPFLLLQGLEDPVCPPEQCDRFLEAVAGCGVPHAYLSF 620 Query: 737 TDEDHGIASSTAHQHIYSHMSHFLQQCFSL 766 E HG Q F + Sbjct: 621 EGEGHGFRRKETMVRALEAELSLYAQVFGV 650 >3O4I-A nrPDB Length = 582 Score = 185 bits (469), Expect = 7e-47, Method: Composition-based stats. Identities = 59/230 (25%), Positives = 96/230 (41%), Gaps = 24/230 (10%) Query: 542 PLLIDVYAGPCSQKADAAFRLNWATYLASTE--NIIVASFDGRGSGYQGDKI-MHAINKR 598 P ++ V+ GP ++ +D +W T+ AS V + RGS G++ + I Sbjct: 361 PTVVLVHGGPFAEDSD-----SWDTFAASLAAAGFHVVMPNYRGSTGYGEEWRLKIIGDP 415 Query: 599 LGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVS 658 G E+ED AAR + G + + I G+SYGGY+T L G+FK G+A A V Sbjct: 416 CG-GELEDVSAAARWARESGL--ASELYIMGYSYGGYMTLCALTMKPGLFKAGVAGASVV 472 Query: 659 RW----EYYDSV---YTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDN 711 W E D+ + E+ G + + R+ + ++ + K+ LIH Sbjct: 473 DWEEMYELSDAAFRNFIEQLTGG-----SREIMRSRSPINHVDRIKE-PLALIHPQNASR 526 Query: 712 VHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFLQ 761 + ++ L+ G F+A D H I + I FL Sbjct: 527 TPLKPLLRLMGELLARGKTFEAHIIPDAGHAINTMEDAVKILLPAVFFLA 576 >6IGR-A nrPDB Length = 656 Score = 153 bits (385), Expect = 3e-37, Method: Composition-based stats. Identities = 112/697 (16%), Positives = 219/697 (31%), Gaps = 104/697 (14%) Query: 101 SDYSVSPDRLFVLLEYNYVKQ----------WRHSYTASYSIYDLNKRQLITEEKIPNNT 150 SD VSPD V + + R Y + + + + +T + Sbjct: 22 SDPQVSPDGKQVAFVLAQISEEDPAKPDKDFARPRYRSGLWLSEGGAARPLTHAETGRGD 81 Query: 151 QWITWSQEGHKLAYVWKND-----IYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEI 205 WS +G LA+V + + + R+T NG+ Sbjct: 82 SAPRWSPDGQNLAFVRSAGEVKAALMLLPLKGGEARRVTH------FKNGV--------- 126 Query: 206 FGAYSALWWSPNGTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVK 265 S WSP+G F+A+ DT DE + Y GA Sbjct: 127 ----SGPQWSPDGRFIAFTTTADT-------EDKRDERGEARVLTRPVYRANGAD----- 170 Query: 266 FFIVNTDSLSSTTTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQ---NYSV 322 + ++ + + ++W + R L + + Sbjct: 171 ----WLPERPAALWLYDVEADKLREWYAPEIGIGALSWWPDSRGVLIVQSEDEWQASQWR 226 Query: 323 MAICDYDKTTLVWNCPTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGYKHI 382 + D T Q+ ++ ++ P F G K + H+ Sbjct: 227 QDVYDLPLPT-ADAPAAPQKLLDWNSAAHGLAPHPDGQRFALIGRPAGK---GNTEHAHL 282 Query: 383 CQFQK------DRKPEQVCTFITKGAWEVISI----EALTSDYLYYISNEYKEMPGGRNL 432 + D + G V + L D L + S + G L Sbjct: 283 YLIENGQHRRLDTGHDHPVGDAVGGDCHVGAFPEGPRWLDGDTLLFSST----VRGSVGL 338 Query: 433 YKIQLTDHTNKKCLSCDLNPERCQYYSVSLSKEAKYYQLGCRGPGLPLYTLHRSTDQKEL 492 + + + D +P+ S + E + P L + + + Sbjct: 339 FTAHIGGGVK----AYDHDPQ--GVISAFTANEHGVALIRESATRFPEVEL----NGQRV 388 Query: 493 RVLEDNSALDKMLQDVQMPSKKLDFIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPC 552 L V+ P + L E W + + +K P L++++ GP Sbjct: 389 TDLHARFPFP-----VREPQRVTFETELGEGEGWVLL-----PEGEQKVPALLNIHGGPH 438 Query: 553 SQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAAR 612 + D L + V + RGS G + AI R GT++ +D + Sbjct: 439 T---DYGHGFTHEFQLMAARGYGVCYSNPRGSVGYGQAWVDAIYGRWGTVDADDLLNFFD 495 Query: 613 QFLKM-GFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDS------ 665 + L+ +D+ + A+ G +YGG++T+ + G + F+ I +S + Sbjct: 496 RCLEAVPRLDAAKTAVMGGAYGGFMTNWITG-HTTRFQAAITDRCISNLISFGGTSDIGL 554 Query: 666 VYTERYMGLP-TPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKAL 724 + + +GL + + + + + EN K L++H D +Q+ Q AL Sbjct: 555 RFWDDELGLDFSRRADALKLWDLSPLQYVENVK-TPTLIVHSVLDHRCPVEQAEQWYAAL 613 Query: 725 VDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFLQ 761 V + + + +E+H ++ S + ++ + Sbjct: 614 HKHQVPVRFVRFPEENHELSRSGRPDRRLTRLNEYFA 650 Score = 40.6 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 26/152 (17%), Positives = 46/152 (30%), Gaps = 21/152 (13%) Query: 92 TFEIFGDSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQ 151 T G S SPD + + + A+ + L + N Sbjct: 73 THAETGRGDSAPRWSPDGQNLAFVRSAGEV-----KAALMLLPLKGGEARRVTHFKNGVS 127 Query: 152 WITWSQEGHKLAYVWKNDIYVKIEPHLPSHRIT-----STGKENVIFNGINDWVYEEEI- 205 WS +G +A+ D K + + +T + G + + W+Y+ E Sbjct: 128 GPQWSPDGRFIAFTTTADTEDKRDERGEARVLTRPVYRANGADWLPERPAALWLYDVEAD 187 Query: 206 ---------FGAYSALWWSPNGTFLAYAQFND 228 G + WW P+ + Q D Sbjct: 188 KLREWYAPEIGIGALSWW-PDSRGVLIVQSED 218 Score = 35.6 bits (80), Expect = 0.087, Method: Composition-based stats. Identities = 21/145 (14%), Positives = 39/145 (26%), Gaps = 33/145 (22%) Query: 55 SYSLRWVSDSEYLYKQENNILLFNAEHGNSSIFL-----ENSTFEIFGDSISDYSVSPDR 109 + RW D + L + E + + L E F + +S SPD Sbjct: 81 DSAPRWSPDGQNL-----AFVRSAGEVKAALMLLPLKGGEARRVTHFKNGVSGPQWSPDG 135 Query: 110 LFVLLEYNYVKQ-----------------------WRHSYTASYSIYDLNKRQLITEEKI 146 F+ + W A+ +YD+ +L Sbjct: 136 RFIAFTTTADTEDKRDERGEARVLTRPVYRANGADWLPERPAALWLYDVEADKLREWYAP 195 Query: 147 PNNTQWITWSQEGHKLAYVWKNDIY 171 ++W + + V D + Sbjct: 196 EIGIGALSWWPDSRGVLIVQSEDEW 220 >5UW6-A nrPDB Length = 750 Score = 143 bits (361), Expect = 2e-34, Method: Composition-based stats. Identities = 41/235 (17%), Positives = 80/235 (34%), Gaps = 32/235 (13%) Query: 520 LNETRFWYQMILPPHFDKSKKYPLLIDVYAG-------PCSQKADAAFRLNWATYLASTE 572 + + F + + P D +K P+ I G PC F +N +++ Sbjct: 464 FDRSEFEVKQVFVPSKDGTK-IPIFIAARKGISLDGSHPCEMHGYGGFGINMMPTFSASR 522 Query: 573 NIIVASFDG-------RGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRV 625 + + G RG G G++ A + +D I AA + G+ ++RV Sbjct: 523 IVFLKHLGGVFCLANIRGGGEYGEEWHKAGFRDKKQNVFDDFISAAEYLISSGYTKARRV 582 Query: 626 AIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSR---WEYYDSVYTERYMGLPTPEDNLD 682 AI G S GG + + + +F C A V + + Y + G D + Sbjct: 583 AIEGGSNGGLLVAACINQRPDLFGCAEANCGVMDMLRFHKFTLGYL--WTGDYGCSDKEE 640 Query: 683 HYR---NSTVMSRAENFKQVE---------YLLIHGTADDNVHFQQSAQISKALV 725 ++ + + + +++ DD V S ++ + Sbjct: 641 EFKWLIKYSPIHNVRRPWEQPGNEETQYPATMILTADHDDRVVPLHSFKLLATMQ 695 >5T88-A nrPDB Length = 616 Score = 123 bits (308), Expect = 3e-28, Method: Composition-based stats. Identities = 62/310 (20%), Positives = 105/310 (33%), Gaps = 27/310 (8%) Query: 462 LSKEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDFIVLN 521 L K+ + L +P Y L+ D LR++E+ + + DF Sbjct: 328 LDKDEERVLLRYTSFTIP-YRLYEFKDD--LRLIEERKVEGEF-------RVEEDFATSK 377 Query: 522 ETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDG 581 + + I+ D+ + + + Y G + F +L I+A+ Sbjct: 378 DGTKVHYFIVKGERDEKRAW---VFGYGG-FNIALTPMFFPQVIPFLKRGGTFIMANL-- 431 Query: 582 RGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVL 641 RG G++ A + +D I + K G+ +VA WG S GG + S L Sbjct: 432 RGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY----KVAAWGRSNGGLLVSATL 487 Query: 642 GSGSGVFKCGIAVAPVSRWE-----YYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENF 696 V + PV Y SV+ Y P+D + + + Sbjct: 488 TQRPDVMDSALIGYPVIDMLRFHKLYIGSVWIPEYGNPEDPKD-REFLLKYSPYHNVDPK 546 Query: 697 KQVEYLLIH-GTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSH 755 K+ LI+ G DD VH + + L + G T H AS + Sbjct: 547 KKYPPTLIYTGLHDDRVHPAHALKFFMKLKEIGAPVYLRVETKSGHMGASPETRARELTD 606 Query: 756 MSHFLQQCFS 765 + F+ + S Sbjct: 607 LLAFVLKTLS 616 >4AMY-A nrPDB Length = 710 Score = 121 bits (303), Expect = 1e-27, Method: Composition-based stats. Identities = 55/313 (17%), Positives = 96/313 (30%), Gaps = 35/313 (11%) Query: 479 PLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDFIVLNETRFWYQMILPPHFDKS 538 P H ++EL K + + ++ + + T+ ++ Sbjct: 404 PGIIYHCDLTKEELEPRVFREVTVKGIDASDYQTVQIFYPSKDGTKIPMFIVHKKGIKLD 463 Query: 539 KKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDG-------RGSGYQGDKI 591 +P + Y G F ++ + + I V G RG G G+ Sbjct: 464 GSHPAFLYGYGG---------FNISITPNYSVSRLIFVRHMGGVLAVANIRGGGEYGETW 514 Query: 592 MHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCG 651 +D AA +K G+ KR+ I G S GG + + +F C Sbjct: 515 HKGGILANKQNCFDDFQCAAEYLIKEGYTSPKRLTINGGSNGGLLVATCANQRPDLFGCV 574 Query: 652 IAVAPVSR---WEYYDS--VYTERYMGLPTPEDNLDHYRNSTVMSR-----AENFKQVEY 701 IA V + Y +T Y G + + + + + A++ + Sbjct: 575 IAQVGVMDMLKFHKYTIGHAWTTDY-GCSDSKQHFEWLIKYSPLHNVKLPEADDIQYPSM 633 Query: 702 LLIHGTADDNVHFQQSAQISKALV-------DAGVDFQAMWYTDEDHGIASSTAH-QHIY 753 LL+ DD V S + L T HG TA Sbjct: 634 LLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQNNPLLIHVDTKAGHGAGKPTAKVIEEV 693 Query: 754 SHMSHFLQQCFSL 766 S M F+ +C ++ Sbjct: 694 SDMFAFIARCLNI 706 >2BKL-A nrPDB Length = 695 Score = 114 bits (284), Expect = 2e-25, Method: Composition-based stats. Identities = 49/285 (17%), Positives = 98/285 (34%), Gaps = 18/285 (6%) Query: 467 KYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDFIVLNETRFW 526 YY +Y ST + EL D + + Q+ +++ + + T+ Sbjct: 377 AYYVFTSFTTPRQIYKTSVSTGKSELWAKVD---VPMNPEQYQV--EQVFYASKDGTKVP 431 Query: 527 YQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGY 586 ++ + P L+ Y G + +A FR + +L + VA+ RG G Sbjct: 432 MFVVHRKDLKRDGNAPTLLYGYGG-FNVNMEANFRSSILPWLDAGGVYAVANL--RGGGE 488 Query: 587 QGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSG 646 G A +D AA ++ + KR+AI+G S GG + + Sbjct: 489 YGKAWHDAGRLDKKQNVFDDFHAAAEYLVQQKYTQPKRLAIYGGSNGGLLVGAAMTQRPE 548 Query: 647 VFKCGIAVAPVSR---WEYYDSV--YTERYMGLPTPEDNLDHYRNSTVMSRAE-NFKQVE 700 ++ + P+ + + S + Y PED + + + + Sbjct: 549 LYGAVVCAVPLLDMVRYHLFGSGRTWIPEYGTAEKPEDFKTLH-AYSPYHHVRPDVRYPA 607 Query: 701 YLLIHGTADDNVHFQQSAQISKALVDAGVDFQ---AMWYTDEDHG 742 L++ DD V + + A+ ++ + + HG Sbjct: 608 LLMMAADHDDRVDPMHARKFVAAVQNSPGNPATALLRIEANAGHG 652 >1YR2-A nrPDB Length = 741 Score = 111 bits (277), Expect = 1e-24, Method: Composition-based stats. Identities = 85/528 (16%), Positives = 147/528 (27%), Gaps = 67/528 (12%) Query: 276 STTTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKT-TLV 334 T + + P + +AW+ D + + +Y++T L Sbjct: 189 RTVKFVGVADGKPLADELKWVKFSGLAWLGNDALLYSRFAEPKEGQAFQALNYNQTVWLH 248 Query: 335 WNCPTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGYK-----HICQFQKDR 389 AT + +SDG + +++ +G H+ + + Sbjct: 249 RLGTPQSADQPVFATPELPKRGHGASV-SSDGR--WVVITSSEGTDPVNTVHVARV-TNG 304 Query: 390 KPEQVCTFIT--KGAWE-VISIEALTSDYLYYISNEYKEMPGGRNLYKIQLTDHTNKKCL 446 K V I K W+ V + D L+++S + + + ++ L+ T + Sbjct: 305 KIGPVTALIPDLKAQWDFVDGV----GDQLWFVSGDGAPLKK---IVRVDLSGSTPRFDT 357 Query: 447 SCDLNPER-------CQYYSVSLSKEAKYYQLGCRGPGLPLYTLH----------RSTDQ 489 + + S +AK L G P + Sbjct: 358 VVPESKDNLESVGIAGNRLFASYIHDAKSQVLAFDLDGKPAGAVSLPGIGSASGLSGRPG 417 Query: 490 KELRVLEDNS------ALDKMLQDVQMPSKKLDFIVLNETRFWYQMILPPHFDKSKKY-- 541 L +S L + + + + F + + P D +K Sbjct: 418 DRHAYLSFSSFTQPATVLALDPATAKTTPWEPVHLTFDPADFRVEQVFYPSKDGTKVPMF 477 Query: 542 -----------PLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGDK 590 P L+ Y G F + T++ S +A+ RG G GD Sbjct: 478 IVRRKDAKGPLPTLLYGYGGFNVALTP-WFSAGFMTWIDSGGAFALANL--RGGGEYGDA 534 Query: 591 IMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKC 650 A + +D I A + G +AI G S GG + V +F Sbjct: 535 WHDAGRRDKKQNVFDDFIAAGEWLIANGVTPRHGLAIEGGSNGGLLIGAVTNQRPDLFAA 594 Query: 651 GIAVAPVSRWEYYDSVYTERY----MGLPTPEDNLDHYRNSTVMSRA-ENFKQVEYLLIH 705 V +D RY G P E + R + L+ Sbjct: 595 ASPAVGVMDMLRFDQFTAGRYWVDDYGYPEKEADWRVLRRYSPYHNVRSGVDYPAILVTT 654 Query: 706 GTADDNVHFQQSAQISKALVDAG---VDFQAMWYTDEDHGIASSTAHQ 750 DD V S + + AL A T HG Q Sbjct: 655 ADTDDRVVPGHSFKYTAALQTAAIGPKPHLIRIETRAGHGSGKPIDKQ 702 >3MUN-A nrPDB Length = 693 Score = 104 bits (259), Expect = 1e-22, Method: Composition-based stats. Identities = 53/278 (19%), Positives = 93/278 (33%), Gaps = 14/278 (5%) Query: 482 TLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDFIVLNETRFWYQMILPPHFDKSKKY 541 TL+R + L SA +D S++ + + TR + Sbjct: 397 TLYRFEPKSGAISLYRASAAPFKPEDYV--SEQRFYQSKDGTRVPLIISYRKGLKLDGSN 454 Query: 542 PLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGT 601 P ++ Y G +F ++ A +L VA+ RG G G A ++ Sbjct: 455 PTILYGYGG-FDVSLTPSFSVSVANWLDLGGVYAVANL--RGGGEYGQAWHLAGTQQNKQ 511 Query: 602 LEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWE 661 +D I AA G+ + R+AI G S GG + V+ + + + V Sbjct: 512 NVFDDFIAAAEYLKAEGYTRTDRLAIRGGSNGGLLVGAVMTQRPDLMRVALPAVGVLDML 571 Query: 662 YYD-----SVYTERYMGLPTPEDNLDHYRNSTVMSRAE-NFKQVEYLLIHGTADDNVHFQ 715 Y + + Y E D+ + + + ++ DD V Sbjct: 572 RYHTFTAGTGWAYDYGTSADSEAMFDYLKGYSPLHNVRPGVSYPSTMVTTADHDDRVVPA 631 Query: 716 QSAQISKALV--DAGVDFQAM-WYTDEDHGIASSTAHQ 750 S + + L +AG Q + T+ HG + A Sbjct: 632 HSFKFAATLQADNAGPHPQLIRIETNAGHGAGTPVAKL 669 >4HVT-A nrPDB Length = 711 Score = 92.6 bits (228), Expect = 7e-19, Method: Composition-based stats. Identities = 41/264 (15%), Positives = 85/264 (32%), Gaps = 13/264 (4%) Query: 513 KKLDFIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTE 572 ++ + + + Y ++ K P L++ Y G A R+ ++ + Sbjct: 450 EQKEATSFDGVKIPYFLVYKKGIKFDGKNPTLLEAYGGFQVINAPYFSRIKNEVWVKNAG 509 Query: 573 NIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSY 632 ++A+ RG G G + + D + + +K + + I G S Sbjct: 510 VSVLANI--RGGGEFGPEWHKSAQGIKRQTAFNDFFAVSEELIKQNITSPEYLGIKGGSN 567 Query: 633 GGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDS-----VYTERYMGLPTPEDNLDHYRNS 687 GG + S+ + +F P+ Y + Y P D L H + Sbjct: 568 GGLLVSVAMTQRPELFGAVACEVPILDMIRYKEFGAGHSWVTEYGDPEIPND-LLHIKKY 626 Query: 688 TVMSRAENFKQVEYLLIHGT-ADDNVHFQQSAQISKAL-VDAGVDFQAMWYTDEDHGIAS 745 + ++ +LI + D VH L + + D HG + Sbjct: 627 APLENLSLTQKYPTVLITDSVLDQRVHPWHGRIFEYVLAQNPNTKTYFLESKDSGHG-SG 685 Query: 746 STAHQ--HIYSHMSHFLQQCFSLR 767 S + + + ++ F L+ Sbjct: 686 SDLKESANYFINLYTFFANALKLK 709 >5N4B-A nrPDB Length = 731 Score = 89.5 bits (220), Expect = 5e-18, Method: Composition-based stats. Identities = 78/527 (14%), Positives = 152/527 (28%), Gaps = 60/527 (11%) Query: 250 VWIPYPK----AGAVNPTVKFFIVNTDSLSSTTTTI-PMQITAPASVTTGD-----HYLC 299 ++ YP G + + + I P + D YL Sbjct: 216 LYQRYPARERHEGTRSDRNAMMCYHKVGTTQEEDIIVYQDNEHPEWIYGADTSEDGKYLY 275 Query: 300 DVAWVSEDRISLQWLRRIQNYSVMAICDYDKTTLVWNCPTTQEHIETSATGWCGRFRPAE 359 + + +L W+ + V + W + + + G + Sbjct: 276 LYQFKDTSKKNLLWVAELDEDGVKSGIH-------WRKVVNEYAADYNIITNHGSLVYIK 328 Query: 360 PHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVCTFITKGAWEVISIEALTSDYLYYI 419 + + I KD I F + K ++ Y++ Sbjct: 329 TNLNAPQYKVITIDLSKDE-PEIRDFIPEEKDAKLAQVNCANEE-------------YFV 374 Query: 420 SNEYKEMPGGRNLYK---IQLTDHTNKKCLSCDL-NPERCQYYSVSLSKEAKYYQLGCRG 475 + + + LY +QLT + + N ++ ++ ++LS G Sbjct: 375 AIYKRNVKDEIYLYSKAGVQLTRLAPDFVGAASIANRQKQTHFFLTLS--------GFNT 426 Query: 476 PGLPLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDFIVLNETRFWYQMILPPHF 535 PG + + + +L + D + S ++ + + T+ ++ Sbjct: 427 PGTIARYDFTAPETQRFSILRTTKVNELDPDDFE--STQVWYESKDGTKIPMFIVRHKST 484 Query: 536 DKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAI 595 + Y G + AD F T+L T I A RG G G++ Sbjct: 485 KFDGTAAAIQYGYGG-FATSADPFFSPIILTFL-QTYGAIFAVPSIRGGGEFGEEWHKGG 542 Query: 596 NKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGS-GVFKCGIAV 654 + +D I AA+ +K + +VAI G + GG + + G F + Sbjct: 543 RRETKVNTFDDFIAAAQFLVKNKYAAPGKVAINGAANGGLLVMGSIVRAPEGTFGAAVPE 602 Query: 655 APVSRWEYYD-----SVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIH-GTA 708 V+ + + Y PE+ Y + + K + LI Sbjct: 603 GGVADLLKFHKFTGGQAWISEYGNPSIPEEFDYIY-PLSPVHNVRTDKVMPATLITVNIG 661 Query: 709 DDNVHFQQSAQISKALVDA--GVDFQAMWYTDE---DHGIASSTAHQ 750 D V S + L + D+ HG+ T Sbjct: 662 DGRVVPMHSFKFIATLQHNVPQNPHPLLIKIDKSWLGHGMGKPTDKN 708 >4BP8-A nrPDB Length = 715 Score = 85.7 bits (210), Expect = 7e-17, Method: Composition-based stats. Identities = 44/258 (17%), Positives = 81/258 (31%), Gaps = 18/258 (6%) Query: 521 NETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFD 580 + T+ ++ D K P ++ Y + F + Y+ +A Sbjct: 455 DGTKVPISLVYDTSIDLKKPNPTMLYGYGS-YGICIEPEFNSRFLPYVDRGMIYAIAHV- 512 Query: 581 GRGSGYQGDKIMHAINKRL-GTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSM 639 RG G G K L D I A + G +++ G S GG + Sbjct: 513 -RGGGEMGRTWYEVGGKYLTKRNTFMDFIACAEHLISSGLTTPAQLSCEGRSAGGLLVGA 571 Query: 640 VLGSGSGVFKCGIAVAPVSRWE---------YYDSVYTERYMGLPTPEDNLDHYRNSTVM 690 VL +F +A P + E G P D+ + + + Sbjct: 572 VLNMRPDLFHVALAGVPFVDVMTTMCDPSIPLTTGEWEE--WGNPNEYKFFDYMNSYSPI 629 Query: 691 SRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDF-QAMWYTDEDHGIASSTAH 749 ++ G D V + + A+ + L + D + + D + G S++ Sbjct: 630 DNVRAQDYPHLMIQAGLHDPRVAYWEPAKWASKLRELKTDSNEVLLKMDLESGHFSASDR 689 Query: 750 QHIYSHMSHFLQQCFSLR 767 + +QQ F L+ Sbjct: 690 YKYLR--ENAIQQAFVLK 705 >2XE4-A nrPDB Length = 751 Score = 80.3 bits (196), Expect = 3e-15, Method: Composition-based stats. Identities = 41/228 (17%), Positives = 69/228 (30%), Gaps = 12/228 (5%) Query: 512 SKKLDFIVLNE-TRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLAS 570 + F + T+ ++ D S+ P ++ Y D F + Y Sbjct: 479 KVERRFATAPDQTKIPLSVVYHKDLDMSQPQPCMLYGYGS-YGLSMDPQFSIQHLPYCDR 537 Query: 571 TENIIVASFDGRGSGYQGDKIMHAINKRL-GTLEVEDQIEAARQFLKMGFVDSKRVAIWG 629 +A RG G K L D I AA + ++A G Sbjct: 538 GMIFAIAHI--RGGSELGRAWYEIGAKYLTKRNTFSDFIAAAEFLVNAKLTTPSQLACEG 595 Query: 630 WSYGGYVTSMVLGSGSGVFKCGIAVAPVSR--WEYYDSVY---TERYMGLPTPEDNL--D 682 S GG + VL +FK +A P D T + P + D Sbjct: 596 RSAGGLLMGAVLNMRPDLFKVALAGVPFVDVMTTMCDPSIPLTTGEWEEWGNPNEYKYYD 655 Query: 683 HYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVD 730 + + + M + ++ G D V + + A+ L + D Sbjct: 656 YMLSYSPMDNVRAQEYPNIMVQCGLHDPRVAYWEPAKWVSKLRECKTD 703 >3WYD-A nrPDB Length = 228 Score = 78.0 bits (190), Expect = 2e-14, Method: Composition-based stats. Identities = 45/223 (20%), Positives = 79/223 (35%), Gaps = 46/223 (20%) Query: 522 ETRFWYQMILPPHFDKSKKYPLLIDVYA-GPCSQKADAAFRLNWATYLASTENIIVASFD 580 + Y++ +P +D +K +PL+I ++ G +++ A IVA Sbjct: 18 GSHMPYRLYVPTTYDGTKAFPLVIALHGMGGDENSYFDSYQRGAFMIEAENRGYIVACPK 77 Query: 581 GR--GSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTS 638 GR S Y G D ++ + + +D R+ + G S GGY T Sbjct: 78 GRQPASMYVGPA-------------ERDVMDVIAEVRRDYKIDPDRIYMTGHSMGGYGTW 124 Query: 639 MVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQ 698 + + VF A+APV+ G P N Sbjct: 125 SIAMNHPDVFA---ALAPVA--------------GGGNPLG-------------MANIAH 154 Query: 699 VEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDH 741 + L++HG D V ++S + +A G + + + DH Sbjct: 155 IPQLVVHGDNDKTVPVERSRVMVEAAKKHGTEIKYIEIPGGDH 197 >5TXC-A nrPDB Length = 705 Score = 73.7 bits (179), Expect = 3e-13, Method: Composition-based stats. Identities = 92/657 (14%), Positives = 186/657 (28%), Gaps = 99/657 (15%) Query: 148 NNTQWITWSQEGHKLAY-VWKNDIYVKIEPHLPSHRITSTGKENVI---------FNGIN 197 T ++ S +G +A+ V + D + + T G + I F I Sbjct: 56 ETTPLLSLSPDGRYVAFQVRQADPVTNLNVFRMVVKAT-DGATDAIDVDVGGEYLFWTIP 114 Query: 198 DWVYEEEIFGAYSALW---WSPNGTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPY 254 W Y + WSP+GT LAY + + V + S Sbjct: 115 SWGYARNAPSGANLTIQPRWSPSGTHLAYLRQDQGRVRVWRASV---------------- 158 Query: 255 PKAGAVNPTVKFFIVNTDSLSSTTTTIPMQITAPASVTTGDHYLCD---VAWVSEDR--- 308 K +P ++ + + + + P + + WV ++R Sbjct: 159 -KGEGASPVIE-DAYDIEDVQWLDDNTLIYSGRP-GFVEAEAEIEREGRRGWVYDERFHP 215 Query: 309 ISLQWLRRIQNYSVMA-ICDYDKTTLVWNCPTTQEHIETSATGWCGRFRPAEPHFTSDGS 367 ++ R ++ S++ + D T PT + +P G Sbjct: 216 LTGARPRVLEPISIVYQVLDLKTGTRRAATPTEVARLREKP----------DPLRAMVGR 265 Query: 368 SFYKI-VSDKDGYKHICQFQKDRKPEQVCTFITKGAWEVISIEALTSDYLYYISNEYKEM 426 + + + +D R + + + + + + Y Sbjct: 266 TTFSVSRTDPQNINAPTTLVARRGEGEPVRCDEEACQNITRMWGDETANVLYFLRREGWA 325 Query: 427 PGGRNLYKIQLTDHTNKKCLSCDLNPERCQYYSVSLSKEAKYYQLGCRGPGLPLYTLHRS 486 LY++ + + C+ ++AK P + + Sbjct: 326 SNEMALYRMPADALKPVRIWHATGLLQGCE-------RQAKRLICAQESALQPRRLVTLN 378 Query: 487 TDQKELRVLEDNSALDKMLQDVQMPSKK-LDFIVLNETRFWYQMILPPHFDKSKKYPLLI 545 ++ L D + L ++P + L N + ++LPP + + PL+I Sbjct: 379 LTSGQMSPLYDPNPD---LSRYRLPKVERLTLRNRNGIEVFSDLVLPPDYQLGTRLPLVI 435 Query: 546 DVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAI---------N 596 Y+ + N LA+ +++ R Sbjct: 436 VQYSSRGFLRGGTG-DENPILPLATAGFAVLSFHSPRSEASYQRFTSPIAQSKAEYSNWR 494 Query: 597 KRLGTLE-VEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSG----------- 644 R L +ED I + G +D RV + G S G L + Sbjct: 495 NRWNILHTLEDLI---DDLDRRGVIDPARVGLTGLSDGATTVHFGLINSHRFAAAVTSSC 551 Query: 645 -SGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLL 703 + F + P S + Y D+ + ++ + A LL Sbjct: 552 CTDSFTASVMNGPRI------SGALKAYGIETDQADDGPFWAATSFVVNASRLDTP--LL 603 Query: 704 IHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFL 760 I ++ + + AL A + + Y +E H +Y+ + Sbjct: 604 IQSADEE---YLGALPGFTALQQARKPVELIIYPNEHHVKWQPAHRLAVYNRTIDWF 657 >5AOA-A nrPDB Length = 286 Score = 72.9 bits (177), Expect = 5e-13, Method: Composition-based stats. Identities = 38/259 (14%), Positives = 79/259 (30%), Gaps = 43/259 (16%) Query: 509 QMPSKKLDFIV-LNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATY 567 +MP ++ ++ + P + + + ++ + G + A FR + Sbjct: 11 EMPGAEVKVYKKVDNVDLKLYIYKPADWKPADRRSAIVFFFGGGWQSGSPAQFRPQCEYF 70 Query: 568 LASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGF---VDSKR 624 + ++ + D R K+ V D A R + VD ++ Sbjct: 71 --AGRGMVAMAADYRVGSRHNVKVADC---------VADAKSAIRWVRQHAAELGVDPQK 119 Query: 625 VAIWGWSYGGYVTSMVLGSGSGVFK------------CGIAVAPVSRWEYYDSVYTERYM 672 + G S GG++ + + + I PV E Sbjct: 120 IVASGGSAGGHLAACTV-MVPDLEAPEEDHTISSQANAAILFNPVLILSR------EGLK 172 Query: 673 GLPTPEDNLDHYRNS--------TVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKAL 724 +D + R + ++ HGTAD+ V F+ ++A+ Sbjct: 173 DHVPRQDWEERLRERLGTEPKAVSPYHHI-RAGLPPMIIFHGTADNTVPFETIRLFAEAM 231 Query: 725 VDAGVDFQAMWYTDEDHGI 743 AG + + + HG Sbjct: 232 KKAGNRCELVPFEGAAHGF 250 >5JRK-A nrPDB Length = 756 Score = 67.2 bits (162), Expect = 3e-11, Method: Composition-based stats. Identities = 92/591 (15%), Positives = 179/591 (30%), Gaps = 108/591 (18%) Query: 214 WSPNGTFLAYAQFN-DTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTD 272 WSP+G +L Y+Q + P + + + + + + ++ V FF+ N + Sbjct: 184 WSPDGKWLWYSQLRAKSDGPRVRFD--EEVTALLGR-------RRSTIDVEVDFFLRNPE 234 Query: 273 SLSSTTTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTT 332 ++ + P++ V W + +Q+ + ++ ++ Sbjct: 235 GDTTRI------MARPSTDRVATRGGGRVLWRGNE---VQFRIETSDGTLGGAFEFVAWN 285 Query: 333 LVWNCPTTQEHIETS-ATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGYKHIC---QFQKD 388 V T + R + + GS I + +G H F Sbjct: 286 RVNRTVRTLAKQRDLLSMSILVGPRGGQLSTSGLGSDRELIETSAEGRPHSYGRVAFDIG 345 Query: 389 RKPEQVCTFITKGAWEVISIEALTSDYLYYISNEYKEMPGGRNLYKIQLTDHTNKKCLSC 448 G VI L Y + L D T + L Sbjct: 346 DSRSAGWKRSRDGKRVVIGTRGLGDAR-----------------YGLALIDKTGVRELRA 388 Query: 449 DLNPERCQYYSVSLSKEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKMLQDV 508 D + RC + G P + ++ L S + ++ Sbjct: 389 DASLTRCG-----FDGMLRSAICVEEGMSRPPRLVRVDLGTDKITDLGPISPRHEEIE-- 441 Query: 509 QMPSKKLDFIVLNETRFWYQ--MILPPHFDKSKKYPLLIDVYAGPCSQKADAAF-----R 561 P + + ++ +W ++LP + ++P ++ + AD F + Sbjct: 442 --PLQTIARTFVSRDGYWSSGYVLLPRGHRAADRHPAVVVTHGT----DADDRFAEPANQ 495 Query: 562 LNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRL------------------GTLE 603 N+ L + +V + S Q +M A++ L G Sbjct: 496 WNYPVQLLAERGYVVLLLND-PSPGQSKDLMDAMHAWLRGKGPPDPETVQQKLWLTGVHS 554 Query: 604 VEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAV--------A 655 ED A + G +D RV I G+S G + + V + S +F+ + Sbjct: 555 FED---AVTELAAEGLIDPARVGIAGYSRGSQMVN-VTVTNSKMFRAASSGDGGFLEPAG 610 Query: 656 PVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQ 715 + YD+VY G DN++ +R A+ + + + Sbjct: 611 YATGRSSYDAVY-----GGAPLSDNIERWRRFAPSLNADKVCAAVLQQVASASPSQI--- 662 Query: 716 QSAQISKALVDAGVDFQAMWYT------DEDHGIASSTAHQHIYSHMSHFL 760 ++ +AL AGV Q +Y DE H +T + Sbjct: 663 ---ELFEALRAAGVATQISYYPGATAASDETHVFYLTTNRLRAMRENIAWF 710 >4Q3K-A nrPDB Length = 260 Score = 59.5 bits (142), Expect = 6e-09, Method: Composition-based stats. Identities = 36/209 (17%), Positives = 68/209 (32%), Gaps = 32/209 (15%) Query: 540 KYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRL 599 K P ++ G +D +YLA N V + + HA+ R Sbjct: 53 KRPAMLIFPGGGYQFCSDREAEPIALSYLAKGYNAFVLRYSVK---------EHAVFPR- 102 Query: 600 GTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSR 659 ++ ED + + ++ ++A+ G+S GG++ + + G + P Sbjct: 103 PLIDAEDALSYLKDNAHALHINPDKIAVIGFSAGGHLATTLATEGKVRPNAVVLGYPALI 162 Query: 660 WEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQ 719 E+Y PTP+ + E + H DD V Sbjct: 163 RH-------EKYWNFPTPKVDQQ---------------TPEMFVFHTFEDDLVPLSHPLY 200 Query: 720 ISKALVDAGVDFQAMWYTDEDHGIASSTA 748 I + L A + + + HG++ Sbjct: 201 IVEELSKANIPVEFHLFKSGVHGLSLGNK 229 >1C7J-A nrPDB Length = 489 Score = 58.3 bits (139), Expect = 1e-08, Method: Composition-based stats. Identities = 48/294 (16%), Positives = 94/294 (31%), Gaps = 34/294 (11%) Query: 499 SALDKMLQDVQMPSKKLDFIVLNETRFW-------YQMILPPHFDKSKKYPLLIDVYAGP 551 LD P D + L+ T Y + P S+ P+++ ++ G Sbjct: 50 DVLDATAYGPVCPQPS-DLLSLSYTELPRQSEDCLYVNVFAPD-TPSQNLPVMVWIHGGA 107 Query: 552 CSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQG---DKIMHAINKRLGTLEVEDQI 608 + L + LA+ +IV + + R + A + LG L DQ Sbjct: 108 F-YLGAGSEPLYDGSKLAAQGEVIVVTLNYRLGPFGFMHLSSFDEAYSDNLGLL---DQA 163 Query: 609 EAARQFLK--MGFV-DSKRVAIWGWSYGGYVTSMVLGSGS---GVFKCGIAVAPVSRWEY 662 A + + F D V ++G S GG ++ L + G+F+ I + SR Sbjct: 164 AALKWVRENISAFGGDPDNVTVFGESAGG-MSIAALLAMPAAKGLFQKAIMESGASRTMT 222 Query: 663 YD------SVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVE-----YLLIHGTADDN 711 + + + + + D L ++ A+ + E L D Sbjct: 223 KEQAASTAAAFLQVLGINESQLDRLHTVAAEDLLKAADQLRIAEKENIFQLFFQPALDPK 282 Query: 712 VHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFLQQCFS 765 ++ + +G+ DE + +S + + L+ Sbjct: 283 TLPEEPEKSIAEGAASGIPLLIGTTRDEGYLFFTSDSDVRSQETLDAALEYSLG 336 >3KSR-A nrPDB Length = 290 Score = 57.5 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 34/234 (14%), Positives = 70/234 (29%), Gaps = 36/234 (15%) Query: 542 PLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGT 601 P ++ V+ SQ A I +FD RG + Sbjct: 29 PGVLFVHGWGGSQH-----HSLVRAREAVGLGCICMTFDLRGHEGYASMRQSVTRAQ--- 80 Query: 602 LEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRW- 660 ++D A Q + +VD+ +A+ G SYGGY+++++ W Sbjct: 81 -NLDDIKAAYDQLASLPYVDAHSIAVVGLSYGGYLSALLTRERP------------VEWL 127 Query: 661 -----EYYDSVYTERYMGLPTPEDNLDHYRNSTV-------MSRAENFKQVEYLLIHGTA 708 Y + ++ + +L YR + ++ +K L+ Sbjct: 128 ALRSPALYKDAHWDQPKVSLNADPDLMDYRRRALAPGDNLALAACAQYKGDVLLV--EAE 185 Query: 709 DDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFLQQ 762 +D + + + DH ++ Q + +L + Sbjct: 186 NDVIVPHPVMRNYADAFTNARSLTSRVIAGADHALSVKEHQQEYTRALIDWLTE 239 >3FCY-A nrPDB Length = 346 Score = 55.2 bits (131), Expect = 1e-07, Method: Composition-based stats. Identities = 48/286 (16%), Positives = 80/286 (27%), Gaps = 53/286 (18%) Query: 491 ELRVLEDNSALDKMLQDVQMPSKKLDFIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAG 550 E+R ++ L + V + + + P + K+P LI + Sbjct: 60 EMRSVDPKIELKESSFQVSFAECYDLYFTGVRGARIHAKYIKPKTEG--KHPALIRFHG- 116 Query: 551 PCSQKADAAFRLNWATYLA-STENIIVASFDGRGSGYQGDKIMHAINKRL------GTLE 603 ++ +W L V + D RG G Q + L G + Sbjct: 117 ------YSSNSGDWNDKLNYVAAGFTVVAMDVRGQGGQSQDVGGVTGNTLNGHIIRGLDD 170 Query: 604 VED------------QIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCG 651 D Q+ + M VD RV + G S GG ++ V K Sbjct: 171 DADNMLFRHIFLDTAQLAGI--VMNMPEVDEDRVGVMGPSQGGGLSLACAALEPRVRKV- 227 Query: 652 IAVAP-------VSRWEYYDSVYTE--RYMGLPTPEDNLD-------HYRNSTVMSRAEN 695 ++ P V + + Y E Y L P + Y + V + A+ Sbjct: 228 VSEYPFLSDYKRVWDLDLAKNAYQEITDYFRLFDPRHERENEVFTKLGYID--VKNLAKR 285 Query: 696 FKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDH 741 K + + G D + Y D H Sbjct: 286 IKGDVLMCV-GLMDQVCPPSTVFAAYNNIQSKK---DIKVYPDYGH 327 >5V5V-A nrPDB Length = 582 Score = 53.7 bits (127), Expect = 3e-07, Method: Composition-based stats. Identities = 39/185 (21%), Positives = 74/185 (40%), Gaps = 20/185 (10%) Query: 486 STDQKELRVLEDNSALDKMLQDVQMPSKKLDFIVLNETRFWYQMILPPHFD--KSKKYPL 543 + + + N + D + ++ +P++ + + PP D S K P+ Sbjct: 84 TDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRD----EATLNPPDTDIRDSGKKPV 139 Query: 544 LIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGR-GSGYQGDKIMHAINKRLGTL 602 ++ ++ G + F + LA+ N+IVA+ + R G A G L Sbjct: 140 MLFLHGGSYMEGTGNMFDGS---VLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLL 196 Query: 603 EVEDQIEAARQFLKMGF---VDSKRVAIWGWSYGGYVTSMVLGSG--SGVFKCGIA--VA 655 DQI+A R + D +R+ I+G G ++++ S G+F+ IA Sbjct: 197 ---DQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGT 253 Query: 656 PVSRW 660 +S W Sbjct: 254 AISSW 258 >2HDW-A nrPDB Length = 367 Score = 51.0 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 42/325 (12%), Positives = 87/325 (26%), Gaps = 73/325 (22%) Query: 477 GLPLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDFIVLNETRFWYQMILPPHFD 536 P T +T +++ ++ +K+ F + LP + Sbjct: 33 TSPAATTSSNTGGTNMQLQLTQEWDKTFPLSAKVEHRKVTFANRYGITLAADLYLPKNRG 92 Query: 537 KSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAIN 596 + ++I GP + + L +A +A + +FD +G G + + + Sbjct: 93 GDRLPAIVI---GGPFGAVKEQSSGL-YAQTMAE-RGFVTLAFDPSYTGESGGQPRNVAS 147 Query: 597 KRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAV-- 654 + T ED A + V+ +R+ + G G + + V + Sbjct: 148 PDINT---EDFSAAVDFISLLPEVNRERIGVIGICGWGGMALNAVAVDKRVKAVVTSTMY 204 Query: 655 -----------APVSR--------------WEYYDSV-------YTE-------RYMGLP 675 V+ W+ +S Y E + Sbjct: 205 DMTRVMSKGYNDSVTLEQRTRTLEQLGQQRWKDAESGTPAYQPPYNELKGGEAQFLVDYH 264 Query: 676 TPEDNLDHYRNSTV-------------------MSRAENFKQVEYLLIHGTADDNVHFQQ 716 Y V ++ + LLIHG + +F + Sbjct: 265 DYYMTPRGYHPRAVNSGNAWTMTTPLSFMNMPILTYIKEISPRPILLIHGERAHSRYFSE 324 Query: 717 SAQISKALVDAGVDFQAMWYTDEDH 741 + A A + + H Sbjct: 325 T-----AYAAAAEPKELLIVPGASH 344 >6AVW-A nrPDB Length = 230 Score = 50.6 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 28/131 (21%), Positives = 43/131 (32%), Gaps = 24/131 (18%) Query: 620 VDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPED 679 + + V I G S GG +T + G + S W + S ++ PE+ Sbjct: 97 TNPENVFICGLSQGGALTLASVLLYPKTLGGGAVL---SGWVPFTSSIISQF-----PEE 148 Query: 680 NLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDE 739 K+ L HGT D V F+ L +AGV + Y Sbjct: 149 A----------------KKTPILWSHGTDDRMVLFEAGQAALPFLKEAGVTCEFKAYPGL 192 Query: 740 DHGIASSTAHQ 750 H I++ Sbjct: 193 GHSISNKELKY 203 >6AAE-A nrPDB Length = 317 Score = 50.6 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 48/283 (16%), Positives = 87/283 (30%), Gaps = 42/283 (14%) Query: 484 HRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDFIVLNETRFWYQMILPPHFDKSKKYPL 543 + E+R + DN A Q+ + I L+ ++ +P D ++ L Sbjct: 22 FSVANPAEIRAVFDNLAAPP-----QVARVENIAISLDGRDLDARLYVPE--DADERPAL 74 Query: 544 LIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLE 603 ++ + G LA V S R + Sbjct: 75 MVYYHGG-GWVIGTLDTHDGTCRALAQKSGCAVLSIAYRLAPEYRYPA-----------P 122 Query: 604 VEDQIEAARQFLKMGF---VDSKRVAIWGWSYGGYVTS----MVLGSGSGVFKCGIAVAP 656 ED +A + VD R+A+ G S GG + + M + + + P Sbjct: 123 AEDCYDALVWAKQNAATLGVDGDRLAVGGDSAGGNLAAAVAIMARDRNGPALRHQLLIYP 182 Query: 657 VSRWEYYDSVYTE-------------RYM-GLPTPEDNLDHYRNSTVMSRAENFKQVEYL 702 V+ ++ + Y E R+ G + ++ + V++ A+ Sbjct: 183 VTDNDFTLASYAENGGGEYYLSTDGMRWFWGHYLGDTAAENAPLAAVLNVADLSGLAPAT 242 Query: 703 LIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIAS 745 +I D + +K L AGV A HG S Sbjct: 243 VITAEYDP--LRDEGIAYAKKLDAAGVPVDAATAPGMIHGFFS 283 >6GI5-A nrPDB Length = 282 Score = 49.4 bits (116), Expect = 5e-06, Method: Composition-based stats. Identities = 46/244 (18%), Positives = 67/244 (27%), Gaps = 44/244 (18%) Query: 523 TRFWYQMILPPHFDKSKKYPLLIDVYA----GPCSQKADAAFRLNWATYLASTENIIVAS 578 R W P + YP++ + G + A L + Sbjct: 39 YRLWLG--RPLQAPPAAGYPVVWMLDGNAAVGALDESTLRRLADGDAPLLVAIGYRTPLR 96 Query: 579 FDGRG--------SGYQGDKIMHAINKRLGTLE-VEDQIE-AAR-QFLKMGFVDSKRVAI 627 D G S Q D+ G + D + R +D+ R + Sbjct: 97 IDRAGRTFDYTPASPGQADQRDPLNGLPSGGADAFLDLLRDGMRPAVAAQAPLDTARQTL 156 Query: 628 WGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNS 687 WG SYGG + L + G F A +P W D GL Sbjct: 157 WGHSYGGLLVLHALFTRPGEFARYAAASPSLWWR--DGAILGERAGLEQRLRG------- 207 Query: 688 TVMSRAENFKQVEYLLIHGTADDNVHF--------QQSAQISKALVD-AGVDFQAMWYTD 738 K+ E LL G+A+ Q A++ L AG+ Sbjct: 208 ---------KRAELLLWRGSAEPASPRGSLKAEPGQAMARLVDDLRRVAGLTLDFQPLDG 258 Query: 739 EDHG 742 HG Sbjct: 259 LGHG 262 >3HXK-A nrPDB Length = 276 Score = 48.7 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 38/223 (17%), Positives = 79/223 (35%), Gaps = 23/223 (10%) Query: 527 YQMILPPHFDKSKKYPLLIDVYAGPC--SQKADAAFRLNWATYLASTENIIVASFD--GR 582 YQ+ P + ++I G SQ+ L +LA +++ ++ + Sbjct: 30 YQLQNPRQNENYTFPAIIICPGGGYQHISQRESDPLAL---AFLAQGYQVLLLNYTVMNK 86 Query: 583 GSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLG 642 G+ Y EV+ Q K ++ ++V + G S GG++ + Sbjct: 87 GTNYN--------FLSQNLEEVQAVFSLIHQNHKEWQINPEQVFLLGCSAGGHLAAWYGN 138 Query: 643 SGSGVFKCGIAV-APVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEY 701 S G+ + PV+ + + + +N+ Y S ++ + Sbjct: 139 SEQIHRPKGVILCYPVTSFTF---GWPSDLSHFNFEIENISEYNISEKVTSS----TPPT 191 Query: 702 LLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIA 744 + H D+ V S + L V F+A ++ HG++ Sbjct: 192 FIWHTADDEGVPIYNSLKYCDRLSKHQVPFEAHFFESGPHGVS 234 >4V2I-A nrPDB Length = 323 Score = 48.7 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 50/301 (16%), Positives = 94/301 (31%), Gaps = 41/301 (13%) Query: 470 QLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDFIVLNETRFWYQ- 528 ++ + L A +L Q + + +T F Sbjct: 1 MPVLEPTTQKFINALSASGGPAIYTLTPAEA-RDVLSGAQSGEIAKPAVDITDTTFAVGP 59 Query: 529 ------MILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGR 582 I+ P + + P+++ + D L+ N + D Sbjct: 60 TGATKVRIIRPQG-NTDRLPVIVYFHGAGWVM-GDTGTHDRLVRELSVRANAALVFVDYE 117 Query: 583 GSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTS--MV 640 S + AI + + + + VD R+AI G S GG +T+ + Sbjct: 118 RSP--EARYPVAIEQDYAVTKY------VAEHSEQLNVDPTRLAIAGDSVGGNMTAVVSL 169 Query: 641 LGS---GSGVFKCGIAVAPVSRWEYYDSVYTER----YMGLPTPEDNLDHYR-------- 685 L G + + PV+ ++ + YTE ++ P + + Y Sbjct: 170 LAQERGGPDI-TAQVLFYPVTDADFDNGSYTEFANGPWLTKPAMDWFWNQYLPEGIDRTD 228 Query: 686 -NSTVMS-RAENF-KQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHG 742 T + +E Q L+I TA+++V + ++ L AGVD Y H Sbjct: 229 PKITPIHATSEQLSGQAPALVI--TAENDVLRDEGEAYARKLSQAGVDVTVTRYNGTIHD 286 Query: 743 I 743 Sbjct: 287 F 287 >3DYV-A nrPDB Length = 251 Score = 48.3 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 44/248 (17%), Positives = 80/248 (32%), Gaps = 32/248 (12%) Query: 532 PPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKI 591 P ++ + +L+ Y G + S + V F G G+ D + Sbjct: 15 PFEYEGTDTGVVLLHAYTG-----SPNDMNFMARALQRSGYGVYVPLFSGHGTVEPLDIL 69 Query: 592 MHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCG 651 + A +V ++G S GG L + G+ G Sbjct: 70 TKGNPDIW----WAESSAAVAHM----TAKYAKVFVFGLSLGGIFAMKALETLPGITAGG 121 Query: 652 IAVAP--------VSRWEYYDSVYTERYMGLPTPEDNLDHY---------RNSTVMSRAE 694 + +P V + Y Y R G + Y + +T ++ Sbjct: 122 VFSSPILPGKHHLVPGFLKYAE-YMNRLAGKSDESTQILAYLPGQLAAIDQFATTVAADL 180 Query: 695 NFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYS 754 N + + D+ V + + Q+ AL++A WY D H I ++AH + Sbjct: 181 NLVKQPTFIGQAGQDELVDGRLAYQLRDALINAAR-VDFHWYDDAKHVITVNSAHHALEE 239 Query: 755 HMSHFLQQ 762 + F+QQ Sbjct: 240 DVIAFMQQ 247 >5XB6-A nrPDB Length = 306 Score = 47.9 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 23/132 (17%), Positives = 47/132 (35%), Gaps = 8/132 (6%) Query: 511 PSKKLDFIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLAS 570 + PP FD++++Y ++ + G ++ A +A LA Sbjct: 4 NKVSFTNSNNPTISLSAVIYFPPKFDETRQYQAIVLSHPGGGVKEQTAG---TYAKKLAE 60 Query: 571 TENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGW 630 + + ++D + YQG+ + ED + +VD+ R+ G Sbjct: 61 -KGFVTIAYD---ASYQGESGGEPRQLENPYIRTEDISAVIDYLTTLSYVDNTRIGAMGI 116 Query: 631 SYG-GYVTSMVL 641 G GY + + Sbjct: 117 CAGAGYTANAAI 128 >2OCI-A nrPDB Length = 254 Score = 46.8 bits (109), Expect = 3e-05, Method: Composition-based stats. Identities = 40/219 (18%), Positives = 66/219 (30%), Gaps = 51/219 (23%) Query: 576 VASFDGRGSGYQ---GDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSY 632 V ++D RG G+ +R D +A + F K+V++ GWS Sbjct: 54 VVAWDPRGYGHSRPPDRDFPADFFER-------DAKDAVDLMKALKF---KKVSLLGWSD 103 Query: 633 GGYVTSMVLGSGSGVFKCGI---AVAPVSR--WEYYD-----SVYTERYMGLPTPEDNLD 682 GG + + A A V+ Y+ S ++ER P + L Sbjct: 104 GGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSER---TRKPLEALY 160 Query: 683 HYR--NSTVMSRAENFKQ------------------VEYLLIHGTADDNVHFQQSAQISK 722 Y T + +Q L++HG D V + I K Sbjct: 161 GYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHK 220 Query: 723 ALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFLQ 761 + + + H + A + FLQ Sbjct: 221 HVKGSR----LHLMPEGKHNLHLRFADE-FNKLAEDFLQ 254 >3HEA-A nrPDB Length = 271 Score = 46.8 bits (109), Expect = 4e-05, Method: Composition-based stats. Identities = 39/271 (14%), Positives = 79/271 (29%), Gaps = 73/271 (26%) Query: 544 LIDVYAGPCSQKADAAFRLNWATYL--ASTENIIVASFDGRGSGYQGDKIMHAINKRLGT 601 ++ + P W + S+ +FD RG G Sbjct: 22 VLFSHGWPLDAD-------MWEYQMEYLSSRGYRTIAFDRRGFGRSDQPWTG-------- 66 Query: 602 LEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIA-------- 653 + + + Q ++ +D K V + G+S GG + + G+ Sbjct: 67 NDYDTFADDIAQLIE--HLDLKEVTLVGFSMGGGDVARYIARHGSARVAGLVLLGAVTPI 124 Query: 654 ---------VAPVSRWEYYDS-VYTERYMGLPTPEDNLDHYRNSTVMSRAENFK------ 697 P+ + + + + +R + V+S+ + Sbjct: 125 FGQKPDYPQGVPLDVFARFKTELLKDRAQFISDFNAPFYGINKGQVVSQGVQTQTLQIAL 184 Query: 698 --------------------------QVEYLLIHGTADDNVHFQQSAQISKALVDAGVDF 731 V L+IHG D V F+ + +++ L+ Sbjct: 185 LASLKATVDCVTAFAETDFRPDMAKIDVPTLVIHGDGDQIVPFETTGKVAAELIKGA--- 241 Query: 732 QAMWYTDEDHGIASSTAHQHIYSHMSHFLQQ 762 + Y D HG A + A Q + + FL++ Sbjct: 242 ELKVYKDAPHGFAVTHAQQ-LNEDLLAFLKR 271 >6FKX-A nrPDB Length = 324 Score = 46.4 bits (108), Expect = 5e-05, Method: Composition-based stats. Identities = 45/256 (17%), Positives = 71/256 (27%), Gaps = 44/256 (17%) Query: 517 FIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTE-NII 575 F R +++ P + +P L+ + +W++ L Sbjct: 65 FTGTGGVRVHAKLLRPVA--PVEPHPALLQFHG-------YTGNSGDWSSRLHYVALGYT 115 Query: 576 VASFDGRGSGYQG------DKIMHAINKRLGTLE-----------VEDQIEAARQFLKMG 618 VA+ D RG + A G + D A+ L M Sbjct: 116 VAALDCRGQAGLSVGEAPVENWSMASYLLRGIDDDAADNLALRHLFLDTARLAQIVLAMD 175 Query: 619 FVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAP-VSRWEYYDSVYTER----YMG 673 VD RVA G+S GG +T + + V P + + + E+ + Sbjct: 176 DVDPDRVAATGYSQGGGLTLACAALEPRI-RLAAPVYPFLCDFRRAWEMDLEKGPYNEIT 234 Query: 674 LPTPEDNLDHYRNSTVMSRAENFKQVEY--------LLIHGTADDNVHFQQSAQISKALV 725 + H R + SR L+ AD S Q A Sbjct: 235 TYFRARDPRHLREEEIFSRLGYVDVQHLAPRVRAEVLMTVSLADKICPP--STQF-AAYN 291 Query: 726 DAGVDFQAMWYTDEDH 741 G Y D H Sbjct: 292 KLGGPKDYRLYPDFAH 307 >6GUD-A nrPDB Length = 292 Score = 46.0 bits (107), Expect = 6e-05, Method: Composition-based stats. Identities = 35/177 (19%), Positives = 64/177 (36%), Gaps = 21/177 (11%) Query: 504 MLQDVQMPSKKLDFIVLNET-RFWYQMILPPHFDKSKK----YPLLIDVYAGP-CSQKAD 557 V +P+ + ++ + + Q+ P H++ + P++ V + Sbjct: 4 RPTPVPLPNSEQFYLENDRGEPYLIQVSWPLHWEDKQTGRGPLPIIYIVDGNALFLTATE 63 Query: 558 AAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRL--------GTLEVEDQIE 609 AA+R A++ A I+ + +G Y + + G D IE Sbjct: 64 AAWRRAAASHFAGGGIIVAIGYPLKGKLYDARRRSFDLTPPTACAPVGYGGADVFLDFIE 123 Query: 610 -----AARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWE 661 A + + V R A++G SYGG + L + F C IA +P W Sbjct: 124 NSVRPAVQA--RFPQVSLAREALYGHSYGGLLALHALFTRPQSFDCYIASSPSIWWN 178 >2XLB-A nrPDB Length = 320 Score = 45.6 bits (106), Expect = 8e-05, Method: Composition-based stats. Identities = 54/298 (18%), Positives = 91/298 (30%), Gaps = 42/298 (14%) Query: 491 ELRVLEDNSALDKMLQDVQMPSKKLDFIVLNETRFWYQMI--LPPHFDKSKKYPLLIDVY 548 ELR +E + L+ P K + L F + I D++ +P L+ + Sbjct: 34 ELRQVEA----EPTLESYDYPVKGVKVYRLTYQSFGHSKIEGFYAVPDQTGPHPALVRFH 89 Query: 549 AGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLG-------- 600 S +NW + RG G D + LG Sbjct: 90 GYNASYDDGIHDIVNW-----ALHGYATFGMLVRGQGGSEDTSVTPGGHALGWMTKGILS 144 Query: 601 ------TLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAV 654 D + A VD R+ + G S GG ++ + S + K +A Sbjct: 145 KDTYYYRGVYLDAVRALEVIQSFPEVDEHRIGVIGGSQGG-ALAIAAAALSDIPKVVVAD 203 Query: 655 AP-VSRWEYYDSVYTER-YMGLPT-------PEDNLDHYRNST---VMSRAENFKQVEYL 702 P +S +E V E+ Y+ + + PE + + +++ A KQ + Sbjct: 204 YPYLSNFERAVDVALEQPYLEINSYFRRNSDPEVEEKAFETLSYFDLINLAGWVKQPTLM 263 Query: 703 LIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFL 760 I G D L D + Y H + + + H L Sbjct: 264 AI-GLIDQVTPPSTVFAAYNHLE---TDKELKVYRYFGHEFIPAFQTEKLSFLQKHLL 317 >5HFN-A nrPDB Length = 311 Score = 45.2 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 37/246 (15%), Positives = 68/246 (27%), Gaps = 33/246 (13%) Query: 530 ILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGD 589 +L P ++ K ++ + F +W + I D RG+ D Sbjct: 85 LLVPKLEEEKLPCVVQYI-----GYNGGRGFPHDW--LFWPSMGYICFVMDTRGTRGILD 137 Query: 590 KIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSM--VLGSGSGV 647 + + D + A VD +R+ I G S GG + L + Sbjct: 138 PRTYYYRR-----VFTDAVRAVEAAASFPQVDQERIVIAGGSQGGGIALAVSALSKKAKA 192 Query: 648 FKCGIA-------VAPVSRWEYYDSVYTERYMGLPTPED----NLDHYRNSTVMSRAENF 696 C + + Y T E+ L ++ +RA Sbjct: 193 LLCDVPFLCHFRRAVQLVDTHPYAE-ITNFLKTHRDKEEIVFRTLSYFDGVNFAARA--- 248 Query: 697 KQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHM 756 ++ L G D+ S + AG + Y +H S + Sbjct: 249 -KIPALFSVGLMDNICPP--STVFAAYNYYAG-PKEIRIYPYNNHEGGGSFQAVEQVKFL 304 Query: 757 SHFLQQ 762 ++ Sbjct: 305 KKLFEK 310 >5X6S-A nrPDB Length = 275 Score = 44.8 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 27/179 (15%), Positives = 59/179 (32%), Gaps = 7/179 (3%) Query: 543 LLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTL 602 +++ ++ C+ + + L+ IV SG D A G Sbjct: 33 IVVAIHY--CTGTGPGYYGDSPYATLSEQYGFIVIYPSSPYSGGCWDVSSQATLTHNGGG 90 Query: 603 EVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEY 662 + DS +V + G S G +T+++ + +F + VS + Sbjct: 91 NSNSIANMVTWTISKYGADSSKVFVTGSSSGAMMTNVMAATYPELFAAATVYSGVSAGCF 150 Query: 663 Y-DSVYTERYMGLPTPED---NLDHYRNSTVMSRAENFKQVEYLLI-HGTADDNVHFQQ 716 Y ++ + + D +H+ + + + I HG+ D ++ Q Sbjct: 151 YSNTNQVDGWNSTCAQGDVITTPEHWASIAEAMYSGYSGSRPRMQIYHGSIDTTLYPQN 209 >5DWD-A nrPDB Length = 240 Score = 44.1 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 27/119 (22%), Positives = 38/119 (31%), Gaps = 10/119 (8%) Query: 651 GIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQV-----EYLLIH 705 G+ A + Y GL PE S ++ E + LLIH Sbjct: 127 GLGPADTILVGFSQGAMMALYTGLRLPEPLKAIIAFSGLIVAPEKLEAEIASKPPVLLIH 186 Query: 706 GTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFLQQCF 764 G DD V S L+D G+D + H IA + FL++ Sbjct: 187 GDLDDVVPVIGSETALPKLIDLGIDARLHISQGSGHTIAQDGL-----DTATAFLREIL 240 >1THG-A nrPDB Length = 544 Score = 44.1 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 41/210 (19%), Positives = 73/210 (34%), Gaps = 25/210 (11%) Query: 449 DLNPERCQYYSVSLSK-EAKYYQLGCR--GPGLPLYTLHRSTDQKELRVLEDNSALDKML 505 DL + Q ++ S +A + C PG L L ++ ++ E L M Sbjct: 36 DLRFKHPQPFTGSYQGLKANDFSPACMQLDPGNSLTLLDKALGLAKVIPEEFRGPLYDMA 95 Query: 506 QDVQMPSKKLDFIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLN-- 563 + + +NE + + P K P+++ +Y G + AA+ N Sbjct: 96 KG---------TVSMNEDCLYLNVFRPAGTKPDAKLPVMVWIYGGAFVYGSSAAYPGNSY 146 Query: 564 WATYLASTENIIVASFDGRGSGY---QGDKIMHAINKRLGTLEVEDQIEAARQ----FLK 616 + + ++ S + R + GD I N G + DQ + Sbjct: 147 VKESINMGQPVVFVSINYRTGPFGFLGGDAITAEGNTNAG---LHDQRKGLEWVSDNIAN 203 Query: 617 MGFVDSKRVAIWGWSYGGYVTSMVLGSGSG 646 G D +V I+G S G + L + G Sbjct: 204 FG-GDPDKVMIFGESAGAMSVAHQLIAYGG 232 >3FCX-A nrPDB Length = 282 Score = 44.1 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 41/243 (16%), Positives = 72/243 (29%), Gaps = 36/243 (14%) Query: 527 YQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIV--ASFDGRGS 584 + + LPP + K L C+++ + AS ++V RG Sbjct: 32 FAVYLPPKAETGKCPALYWLS-GLTCTEQ--NFISKSGYHQSASEHGLVVIAPDTSPRGC 88 Query: 585 GYQGD-----------KIMHAINKRLGTLEV--EDQIEAARQFLKMGF-VDSKRVAIWGW 630 +G+ + A T E Q + F VD +R++I+G Sbjct: 89 NIKGEDESWDFGTGAGFYVDATEDPWKTNYRMYSYVTEELPQLINANFPVDPQRMSIFGH 148 Query: 631 SYGGYVTSMVLGSGSGVFKCGIAVAPVSR-----WEYYDSVYTERYMGLPTPEDNLDHYR 685 S GG+ + G +K A AP+ W Y+G ++ Sbjct: 149 SMGGHGALICALKNPGKYKSVSAFAPICNPVLCPWGKKA---FSGYLGTD-----QSKWK 200 Query: 686 NSTVMSRAENFKQVEY-LLIHGTADDNVHFQQSAQ---ISKALVDAGVDFQAMWYTDEDH 741 +++ + +LI DD A + + D DH Sbjct: 201 AYDATHLVKSYPGSQLDILIDQGKDDQFLLDGQLLPDNFIAACTEKKIPVVFRLQEDYDH 260 Query: 742 GIA 744 Sbjct: 261 SYY 263 >3E4D-A nrPDB Length = 278 Score = 43.7 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 35/192 (18%), Positives = 68/192 (35%), Gaps = 26/192 (13%) Query: 581 GRGSGYQGDKIMH--AINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTS 638 G+G+G+ D + + ++ + E+ Q + D R +I+G S GG+ Sbjct: 99 GKGAGFYLDATEEPWSEHYQMYSYVTEELPALIGQHFR---ADMSRQSIFGHSMGGHGAM 155 Query: 639 MVLGSGSGVFKCGIAVAPVS-----RWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRA 693 + FK A AP+ W E+Y+G Y +++ Sbjct: 156 TIALKNPERFKSCSAFAPIVAPSSADWSEPA---LEKYLGAD--RAAWRRYDACSLVE-- 208 Query: 694 ENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIY 753 + + E+L+ G AD + + + +A+ TD + + H Y Sbjct: 209 DGARFPEFLIDQGKADS---------FLEKGLRPWLFEEAIKGTDIGLTLRMHDRYDHSY 259 Query: 754 SHMSHFLQQCFS 765 +S F+ Sbjct: 260 YFISTFMDDHLK 271 >2WQZ-A nrPDB Length = 588 Score = 43.3 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 37/147 (25%), Positives = 57/147 (38%), Gaps = 18/147 (12%) Query: 527 YQMILPPHFDK----SKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGR 582 Y I P D + K P+++ ++ G + + LAS N+IV + + R Sbjct: 117 YLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGS---ILASYGNVIVITINYR 173 Query: 583 -GSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFV---DSKRVAIWGWSYGGYVTS 638 G A G L DQI+A R + D KRV I+G G S Sbjct: 174 LGILGFLSTGDQAAKGNYGLL---DQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVS 230 Query: 639 MVLGSG--SGVFKCGI--AVAPVSRWE 661 ++ S G+F+ I + +S W Sbjct: 231 LLTLSHYSEGLFQKAIIQSGTALSSWA 257 >3BIX-A nrPDB Length = 574 Score = 43.3 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 35/150 (23%), Positives = 58/150 (38%), Gaps = 19/150 (12%) Query: 527 YQMILPPHFDK----SKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGR 582 Y I P D P+++ ++ G + + + LAS N+IV + + R Sbjct: 113 YLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGS---VLASYGNVIVITVNYR 169 Query: 583 -GSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLK-MGFV--DSKRVAIWGWSYGGYVTS 638 G A G L D I+A R + +GF D R+ ++G GG + Sbjct: 170 LGVLGFLSTGDQAAKGNYGLL---DLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVN 226 Query: 639 MVLGSG---SGVFKCGIA--VAPVSRWEYY 663 ++ S G+F+ IA +S W Sbjct: 227 LLTLSHYSEKGLFQRAIAQSGTALSSWAVS 256 >1C5K-A nrPDB Length = 439 Score = 42.9 bits (99), Expect = 6e-04, Method: Composition-based stats. Identities = 25/128 (19%), Positives = 43/128 (33%), Gaps = 19/128 (14%) Query: 123 RHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQEGHKLAYVWKNDIYVKIEPHLPSHR 182 + Y S YD + ++ + P WS +G KLAYV + + Sbjct: 178 QFPYELRVSDYDGYNQFVVH--RSPQPLMSPAWSPDGSKLAYVT-----FESGRSALVIQ 230 Query: 183 ITSTGKENVIFNGINDWVYEEEIFGAYSAL-WWSPNGTFLAYAQFNDTGVPLIEYSFYSD 241 + G V + F ++ +SP+G+ LA+A + L S Sbjct: 231 TLANG-----------AVRQVASFPRHNGAPAFSPDGSKLAFALSKTGSLNLYVMDLASG 279 Query: 242 ESLQYPKT 249 + Q Sbjct: 280 QIRQVTDG 287 Score = 39.8 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 28/146 (19%), Positives = 44/146 (30%), Gaps = 27/146 (18%) Query: 57 SLRWVSDSEYLYKQENNILLFNAEHGNSSIFLEN------STFEIFGDSISDYSVSPDRL 110 S W D + + E G S++ ++ F + SPD Sbjct: 205 SPAWSPDG-------SKLAYVTFESGRSALVIQTLANGAVRQVASFPRHNGAPAFSPDGS 257 Query: 111 FVLLEYNYVKQWRHSYTASYSIY--DLNKRQLITEEKIPNNTQWITWSQEGHKLAYVWKN 168 + S T S ++Y DL Q+ +N TW + LA+ Sbjct: 258 KLAFAL--------SKTGSLNLYVMDLASGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQ 309 Query: 169 ----DIYVKIEPHLPSHRITSTGKEN 190 +Y RIT G +N Sbjct: 310 AGRPQVYKVNINGGAPQRITWEGSQN 335 Score = 29.0 bits (63), Expect = 8.9, Method: Composition-based stats. Identities = 18/101 (17%), Positives = 39/101 (38%), Gaps = 4/101 (3%) Query: 214 WSPNGTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPT-VKFFIVNTD 272 WSP+G+ LAY F ++G + ++ +++ + + A A +P K + Sbjct: 208 WSPDGSKLAYVTF-ESGRSALVIQTLANGAVRQVASFP-RHNGAPAFSPDGSKLAFALSK 265 Query: 273 SLSSTTTTIPMQITAPASVTTGDHYLCDVAWVSE-DRISLQ 312 + S + + VT G + W + ++ Sbjct: 266 TGSLNLYVMDLASGQIRQVTDGRSNNTEPTWFPDSQNLAFT 306 >3I6Y-A nrPDB Length = 280 Score = 42.5 bits (98), Expect = 7e-04, Method: Composition-based stats. Identities = 49/258 (18%), Positives = 95/258 (36%), Gaps = 37/258 (14%) Query: 527 YQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENI--IVASFDGRGS 584 + + LPP K P+L + CS + + A LA+ I + RG Sbjct: 33 FAIYLPPQASTGAKVPVLYWLSGLTCSDE--NFMQKAGAQRLAAELGIAIVAPDTSPRGE 90 Query: 585 G---------YQGD-KIMHAINKRLGT-LEVED-QIEAARQFLKMGFVDSKRVAIWGWSY 632 G QG ++A ++ D + + ++ F S + AI G S Sbjct: 91 GVADDEGYDLGQGAGFYVNATQAPWNRHYQMYDYVVNELPELIESMFPVSDKRAIAGHSM 150 Query: 633 GGYVTSMVLGSGSGVFKCGIAVAPVSR-----WEYYDSVYTERYMGLPTPEDNLDHYRNS 687 GG+ + ++ A +P++ W +T Y+G T + ++ Sbjct: 151 GGHGALTIALRNPERYQSVSAFSPINNPVNCPWG--QKAFTA-YLGKDT---DTWREYDA 204 Query: 688 TVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASST 747 +++ RA + V L+ G AD+ + Q ++ +A + Y E + S Sbjct: 205 SLLMRAAK-QYVPALVDQGEADNFLAEQLKPEVLEAAASSNN------YPLE---LRSHE 254 Query: 748 AHQHIYSHMSHFLQQCFS 765 + H Y ++ F++ Sbjct: 255 GYDHSYYFIASFIEDHLR 272 >3RAR-A nrPDB Length = 534 Score = 42.5 bits (98), Expect = 7e-04, Method: Composition-based stats. Identities = 34/172 (19%), Positives = 62/172 (36%), Gaps = 22/172 (12%) Query: 499 SALDKMLQDVQMPSKKLDFIV-LNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKAD 557 L K D+ M SK + + +E ++ PP P+++ ++ G Sbjct: 71 ENLPKAALDLVMQSKVFEAVSPSSEDCLTINVVRPPGTKAGANLPVMLWIFGGGFEVGGT 130 Query: 558 AAFRLNWATY--LASTENIIVASFDGRGSGYQ---GDKIMHAINKRLGTLEVEDQIEAAR 612 + F +A + II S + R S + GD+I + G ++DQ + Sbjct: 131 STFPPAQMITKSIAMGKPIIHVSVNYRVSSWGFLAGDEIKAEGSANAG---LKDQRLGMQ 187 Query: 613 QFLKMGFV---DSKRVAIWGWSYGGYVTSMVLGSGSG---------VFKCGI 652 D +V I+G S G ++ M + +F+ GI Sbjct: 188 WVADNIAAFGGDPTKVTIFGESAGS-MSVMCHILWNDGDNTYKGKPLFRAGI 238 >1K4Y-A nrPDB Length = 534 Score = 42.1 bits (97), Expect = 8e-04, Method: Composition-based stats. Identities = 35/170 (20%), Positives = 67/170 (39%), Gaps = 16/170 (9%) Query: 498 NSALDKMLQDVQMPSKKLDFIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKAD 557 ++ ML ++ K+ + +E + + P K + P+++ ++ G Sbjct: 68 DAVSGHMLSELFTNRKENIPLKFSEDCLYLNIYTPADLTKRGRLPVMVWIHGGGLMVGGA 127 Query: 558 AAFRLNWATYLASTENIIVASFDGRGS--GYQGDKIMHAINKRLGTLEVEDQIEAARQ-- 613 + + L++ EN++V + R G+ H+ G L DQ+ A R Sbjct: 128 STYD---GLALSAHENVVVVTIQYRLGIWGFFSTGDEHS-RGNWGHL---DQVAALRWVQ 180 Query: 614 --FLKMGFVDSKRVAIWGWSYGGYVTSMVLGS--GSGVFKCGIAVAPVSR 659 G D V I+G S GG S++L S +F I+ + V+ Sbjct: 181 DNIANFG-GDPGSVTIFGESAGGQSVSILLLSPLTKNLFHRAISESGVAL 229 >4B6G-A nrPDB Length = 283 Score = 42.1 bits (97), Expect = 8e-04, Method: Composition-based stats. Identities = 26/182 (14%), Positives = 63/182 (34%), Gaps = 13/182 (7%) Query: 570 STENIIVASFDGRGSGYQGDKIMHAINKRLGTL-EVEDQI-EAARQFLKMGFVDSKRVAI 627 S V + D G ++A + ++ D I + ++ F + + +I Sbjct: 90 SPRGEQVPNDDAYDLGQSAGFYLNATEQPWAANYQMYDYILNELPRLIEKHFPTNGKRSI 149 Query: 628 WGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTER----YMGLPTPEDNLDH 683 G S GG+ ++ ++ A +P+ + E+ Y+G + Sbjct: 150 MGHSMGGHGALVLALRNQERYQSVSAFSPILSPSLVP--WGEKAFTAYLGKD--REKWQQ 205 Query: 684 YRNSTVMSRAENFKQVEYLLIHGTADDNVHFQ-QSAQISKALVDAGVDFQAMWYTDEDHG 742 Y ++++ + +K + G D+ + Q ++ + A ++ DH Sbjct: 206 YDANSLIQQ--GYKVQGMRIDQGLEDEFLPTQLRTEDFIETCRAANQPVDVRFHKGYDHS 263 Query: 743 IA 744 Sbjct: 264 YY 265 >3LS2-A nrPDB Length = 280 Score = 42.1 bits (97), Expect = 9e-04, Method: Composition-based stats. Identities = 46/248 (18%), Positives = 83/248 (33%), Gaps = 29/248 (11%) Query: 527 YQMILPPHFDKSKKYPLLIDVYAGPCS----QKADAAFRLNWATYLA------STENIIV 576 + + LPP +S K P+L + C+ + AF+ +A S V Sbjct: 31 FAVFLPPGASESNKVPVLYWLSGLTCTDENFMQKAGAFKKAAELGIAIVAPDTSPRGDNV 90 Query: 577 ASFDG----RGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSY 632 + D +G+G+ + N + + ++ F + AI G S Sbjct: 91 PNEDSYDFAQGAGFYVNATQAPYNTHFNMYDY--VVNELPALIEQHFPVTSTKAISGHSM 148 Query: 633 GGYVTSMVLGSGSGVFKCGIAVAPVSR-----WEYYDSVYTERYMGLPTPEDNLDHYRNS 687 GG+ M+ + A +P+ W Y+G + Y + Sbjct: 149 GGHGALMIALKNPQDYVSASAFSPIVNPINCPWGVKA---FTGYLGAD--KTTWAQYDSC 203 Query: 688 TVMSRAENFKQVEYLLIHGTAD---DNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIA 744 +M++AE + L+ G AD D Q+ D + + D + Sbjct: 204 KLMAKAEQSNYLPMLVSQGDADNFLDEQLKPQNLVAVAKQKDYPLTLEMQTGYDHSYFFI 263 Query: 745 SSTAHQHI 752 SS QH+ Sbjct: 264 SSFIDQHL 271 >4BZW-A nrPDB Length = 282 Score = 42.1 bits (97), Expect = 9e-04, Method: Composition-based stats. Identities = 37/239 (15%), Positives = 70/239 (29%), Gaps = 37/239 (15%) Query: 523 TRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGR 582 T +W I F+ + YP++I G + + +A+ + +V + Sbjct: 18 TAYWLDQI--SDFETAVDYPIMIICPGGGFTYHSGREEAPIATRMMAAGMHTVVLN---- 71 Query: 583 GSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYV------ 636 + ++ I+ VD +R+ + G+S GG+V Sbjct: 72 ----YQLIVGDQSVYPWALQQLGATIDWITTQASAHHVDCQRIILAGFSAGGHVVATYNG 127 Query: 637 --------TSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNST 688 T L G I PV G PT + Sbjct: 128 VATQPELRTRYHLDHYQGQHAAIILGYPVIDLTA----------GFPTTSAARNQITTDA 177 Query: 689 VMSRAENFK---QVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIA 744 + A+ + D++V S + +A++ V + HG+A Sbjct: 178 RLWAAQRLVTPASKPAFVWQTATDESVPPINSLKYVQAMLQHQVATAYHLFGSGIHGLA 236 >4NOX-A nrPDB Length = 746 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 44/281 (15%), Positives = 84/281 (29%), Gaps = 52/281 (18%) Query: 91 STFEIFGDSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQL--ITEEKIPN 148 T +F S + ++ ++ + + + S + I+ + ++ + + I + Sbjct: 404 RTLNLFSVSDVKMHWQSEGTYLCVKVDRHSKSKKSQATTLEIFRVKEKGVPVEVVDTIKD 463 Query: 149 NTQWITWSQEGHKLAYVWKNDIYVKIEPHL-----PSHRITSTGKENVIFNGINDWVYEE 203 W +G + I EP P ++ E N + + + Sbjct: 464 TVINFAWEPKGDRFV------IITTPEPVGATAVPPKTSVSFFCPELKKGNQVGSFKHLR 517 Query: 204 EIFGA-YSALWWSPNGTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNP 262 + ++A++WSP G F+ A ++T +E+ Sbjct: 518 TLEKKNHNAIYWSPKGRFVVIATVHNTQSSDLEF-------------------------- 551 Query: 263 TVKFFIVNTDSLSSTTTTIPMQITAPASVTTGDHY-LCDVAWVSEDRISLQWLRRIQNYS 321 + D + TGDHY + DV W R W ++ Sbjct: 552 ------WDLDFDGEKPENEKDLAACLQLMGTGDHYGITDVEWDPSGRYVATWASAWKHTM 605 Query: 322 VMAICDYDKTTLVWNCPTTQEHIETSATGWCGRFRPAEPHF 362 YD +EHIE W R RP Sbjct: 606 ENGYHLYDFKGE----LLREEHIE-KFKQWQWRPRPPTLLT 641 >3RLI-A nrPDB Length = 270 Score = 41.4 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 35/226 (15%), Positives = 62/226 (27%), Gaps = 47/226 (20%) Query: 530 ILPPHFDKSKKYPLL-----IDVYAGPCSQKADAAF-------RLNWATYLASTENIIVA 577 ++P S++YP+L GP F R Y + + + Sbjct: 14 LVPRGSHMSEQYPVLSGAEPFYAENGPVGVLLVHGFTGTPHSMRPLAEAYAKAGYTVCLP 73 Query: 578 SFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVT 637 G G+ Y + + V E + + + G S GG +T Sbjct: 74 RLKGHGTHY--EDMERTTFHDW----VASVEEGYGWLKQRCQT----IFVTGLSMGGTLT 123 Query: 638 SMVLGSGSGVFKCGIA-VAPVSRWEYYDSVYT-----ERYM-----GLPTPEDNLDHYRN 686 + + CGI + + T RY+ L P+ Y Sbjct: 124 LYLAEHHPDI--CGIVPINAAVDIPAIAAGMTGGGELPRYLDSIGSDLKNPDVKELAYEK 181 Query: 687 ---STVMSRAENFKQV---------EYLLIHGTADDNVHFQQSAQI 720 ++++ A Q L+ D V + I Sbjct: 182 TPTASLLQLARLMAQTKAKLDRIVCPALIFVSDEDHVVPPGNADII 227 >5XKS-A nrPDB Length = 256 Score = 41.4 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 31/240 (12%), Positives = 57/240 (23%), Gaps = 49/240 (20%) Query: 549 AGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQI 608 P S + Y + + G G+ Y + + + ++ Sbjct: 31 GSPQSMRPLG------EAYHEAGYTVCGPRLKGHGTHY--EDMEKTTCQDW----IDSVE 78 Query: 609 EAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGI--------------AV 654 + + G S GG +T + + CGI A+ Sbjct: 79 AGYEWLKNRCGT----IFVTGLSMGGTLTLYMAEHHPEI--CGIAPINAAINMPALAGAL 132 Query: 655 APVSRWEYYDSVYTERYMGLPTPEDNLDHYRN------STVMSRAENFKQV------EYL 702 A V + + P Y ++ E K + Sbjct: 133 AGVGDLPRFLDAIGS---DIKKPGVKELAYEKTPAASIRQIVQLMERVKTDLHKITCPAI 189 Query: 703 LIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFLQQ 762 L D V + I + A + + D H Q I F ++ Sbjct: 190 LFCSDEDHVVPPDNAPFIYDHIASADK--KLVRLPDSYHVATLDNDRQKIIDTSLAFFKK 247 >2D81-A nrPDB Length = 318 Score = 41.4 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 30/131 (22%), Positives = 52/131 (39%), Gaps = 8/131 (6%) Query: 620 VDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCG---IAVAPVS--RWEYYDSVYTERYMGL 674 V+ V++ G + GGY+ + + + S VF G A P R +YY S Y + Sbjct: 8 VNPNSVSVSGLASGGYMAAQLGVAYSDVFNVGFGVFAGGPYDCARNQYYTSCMYNGYPSI 67 Query: 675 PTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKAL--VDAGVDFQ 732 TP N+ + + ++ N Q + + G++D V Q+ L D + Sbjct: 68 TTPTANMKSW-SGNQIASVANLGQRKIYMWTGSSDTTVGPNVMNQLKAQLGNFDNSANVS 126 Query: 733 AMWYTDEDHGI 743 + T H Sbjct: 127 YVTTTGAVHTF 137 >2W6C-X nrPDB Length = 586 Score = 41.4 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 31/142 (21%), Positives = 54/142 (38%), Gaps = 10/142 (7%) Query: 527 YQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGY 586 Y I P K +++ +Y G + + YLA TE +++ S R + Sbjct: 117 YLNIWVPSPRP-KSTTVMVWIYGG-GFYSGSSTLDVYNGKYLAYTEEVVLVSLSYRVGAF 174 Query: 587 QGDKIMHAINKRLGTLEVEDQIEAARQF---LKMGFVDSKRVAIWGWSYGGYVTSMVLGS 643 + + G + + DQ A + ++ D K V I+G S GG M + S Sbjct: 175 GFLALHGSQEAP-GNVGLLDQRMALQWVHDNIQFFGGDPKTVTIFGESAGGASVGMHILS 233 Query: 644 GS--GVFKCGI--AVAPVSRWE 661 +F+ I + +P W Sbjct: 234 PGSRDLFRRAILQSGSPNCPWA 255 >2X8B-A nrPDB Length = 583 Score = 41.0 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 27/142 (19%), Positives = 52/142 (36%), Gaps = 9/142 (6%) Query: 527 YQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGY 586 Y + P+ + P+L+ +Y G ++ + +L E ++ S + R + Sbjct: 98 YLNVWTPYPRPTSPTPVLVWIYGG-GFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAF 156 Query: 587 QGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFV---DSKRVAIWGWSYGGYVTSMVLGS 643 + + G + + DQ A + + D V ++G S G M L S Sbjct: 157 GFLALPGSREAP-GNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLS 215 Query: 644 GS--GVFKCGI--AVAPVSRWE 661 G+F + + AP W Sbjct: 216 PPSRGLFHRAVLQSGAPNGPWA 237 >5FV4-A nrPDB Length = 544 Score = 40.2 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 34/164 (20%), Positives = 64/164 (39%), Gaps = 14/164 (8%) Query: 502 DKMLQDVQMPSKKLDFIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFR 561 +M D+ K+ +E + + P K + P+++ ++ G + + Sbjct: 77 GQMTSDLFTNRKERLIPEFSEDCLYLNIYTPADLTKRGRLPVMVWIHGGGLVVGGASTYD 136 Query: 562 LNWATYLASTENIIVASFDGRGS--GYQGDKIMHAINKRLGTLEVEDQIEAARQFLK--M 617 LA+ EN++V + R G+ H+ G L DQ+ A + Sbjct: 137 ---GLALAAHENVVVVAIQYRLGIWGFFSTGDEHS-RGNWGHL---DQVAALHWVQENIA 189 Query: 618 GF-VDSKRVAIWGWSYGGYVTSMVLGS--GSGVFKCGIAVAPVS 658 F D V I+G S GG S+++ S +F I+ + V+ Sbjct: 190 NFGGDPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVA 233 >1MX5-A nrPDB Length = 548 Score = 40.2 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 32/150 (21%), Positives = 61/150 (40%), Gaps = 14/150 (9%) Query: 518 IVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVA 577 + L+E + + P K + P+++ ++ G A + + LA+ EN++V Sbjct: 92 LKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYD---GLALAAHENVVVV 148 Query: 578 SFDGRGS--GYQGDKIMHAINKRLGTLEVEDQIEAARQF---LKMGFVDSKRVAIWGWSY 632 + R G+ H+ G L DQ+ A R + + V I+G S Sbjct: 149 TIQYRLGIWGFFSTGDEHS-RGNWGHL---DQVAALRWVQDNIASFGGNPGSVTIFGESA 204 Query: 633 GGYVTSMVLGS--GSGVFKCGIAVAPVSRW 660 GG S+++ S +F I+ + V+ Sbjct: 205 GGESVSVLVLSPLAKNLFHRAISESGVALT 234 >4PF1-A nrPDB Length = 626 Score = 40.2 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 22/98 (22%), Positives = 33/98 (33%), Gaps = 3/98 (3%) Query: 565 ATYLASTENIIVASFDGRGSGYQGDKIMHAINKRL---GTLEVEDQIEAARQFLKMGFVD 621 T A+ I+ G+ G + + L GT D + +K Sbjct: 92 DTTSAARYIIVYQDVRGKYGSEGGYMMNKPLTGPLNTTGTDHSTDTYDTIDWLVKNIPES 151 Query: 622 SKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSR 659 + RVA G SY GY T M + K + A + Sbjct: 152 NGRVAAIGGSYEGYTTLMCTINPHPALKAVVPFASMVD 189 >5FDF-A nrPDB Length = 337 Score = 39.8 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 40/265 (15%), Positives = 72/265 (27%), Gaps = 45/265 (16%) Query: 530 ILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSG---- 585 +L P ++ K ++ + F +W + + V G+GSG Sbjct: 85 LLVPKLEEEKLPCVVQYI-----GYNGGRGFPHDWLFWPSMGYICFVMDTRGQGSGWLKG 139 Query: 586 -------------YQGDKIMHAINKRLGTL--EVEDQIEAARQFLKMGFVDSKRVAIWGW 630 Y G ++ R D + A VD +R+ I G Sbjct: 140 DTPDYPEGPVDPQYPGFMTRGILDPRTYYYRRVFTDAVRAVEAAASFPQVDQERIVIAGG 199 Query: 631 SYGGYVTSM--VLGSGSGVFKCGIA-------VAPVSRWEYYDSVYTERYMGLPTPED-- 679 S GG + L + C + + Y T E+ Sbjct: 200 SQGGGIALAVSALSKKAKALLCDVPFLCHFRRAVQLVDTHPYAE-ITNFLKTHRDKEEIV 258 Query: 680 --NLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYT 737 L ++ +RA ++ L G D+ S + AG + Y Sbjct: 259 FRTLSYFDGVNFAARA----KIPALFSVGLMDNICPP--STVFAAYNYYAG-PKEIRIYP 311 Query: 738 DEDHGIASSTAHQHIYSHMSHFLQQ 762 +H S + ++ Sbjct: 312 YNNHEGGGSFQAVEQVKFLKKLFEK 336 >4WY5-A nrPDB Length = 332 Score = 39.8 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 47/310 (15%), Positives = 100/310 (32%), Gaps = 58/310 (18%) Query: 465 EAKYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDFIVLNETR 524 A + P + L + E R L N L ++++ + + + Sbjct: 12 YAAAFAAMKERPPIHTLDLKVVRESSEARQLAANIKLPEVIE-------EDKVVESDGKT 64 Query: 525 FWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGS 584 ++ PP + + P+LI ++ G + L N++ D S Sbjct: 65 LKLTIVRPPG-TEDQILPVLIFLHGGGFV-FGSKYTHIKPVRDLTVKANVVTVFVDYSLS 122 Query: 585 GYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGF---VDSKRVAIWGWSYGGYV----- 636 K AI E+ A + ++++ +A+ G S G + Sbjct: 123 P--EAKFPTAI---------EEIYAAILWVRENASSLNINAEALAVAGDSAGATLSAAVS 171 Query: 637 ---------------------TSMVLGSGS--GVFKCGIAVAPVSRWEYYDSVYTERYMG 673 T++ +F G + +++ + Y Sbjct: 172 IYAKEKGLSAAIKTQVLIYPATAVSHAKYESYKLFGNGDYILSAEDLKFFSNAY------ 225 Query: 674 LPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQA 733 LP P L+ + ++ + + + L+ TA+ +V + + ++ L +AGVD A Sbjct: 226 LPAPASELNDKLATLELATKADLEGLPPALLF-TAESDVLRDEGEKYAQQLAEAGVDVAA 284 Query: 734 MWYTDEDHGI 743 + HG Sbjct: 285 VRVLGAVHGF 294 >4R40-A nrPDB Length = 411 Score = 39.8 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 23/121 (19%), Positives = 41/121 (33%), Gaps = 19/121 (15%) Query: 130 YSIYDLNKRQLITEEKIPNNTQWITWSQEGHKLAYVWKNDIYVKIEPHLPSHRITSTGKE 189 S YD + ++ + P WS +G K+AYV + + + G Sbjct: 165 VSDYDGYNQFVVH--RSPEPLMSPAWSPDGSKIAYVT-----FESGKSALVIQTLANGAI 217 Query: 190 NVIFNGINDWVYEEEIFGAYSAL-WWSPNGTFLAYAQFNDTGVPLIEYSFYSDESLQYPK 248 + + F ++ +SP+GT LA+A + L S + Q Sbjct: 218 RQVAS-----------FPRHNGAPAFSPDGTKLAFALSKSGSLNLYVMDLASGQISQVTD 266 Query: 249 T 249 Sbjct: 267 G 267 Score = 39.4 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 26/144 (18%), Positives = 43/144 (29%), Gaps = 23/144 (15%) Query: 57 SLRWVSDSEYLYKQENNILLFNAEHGNSSIFLEN------STFEIFGDSISDYSVSPDRL 110 S W D + I E G S++ ++ F + SPD Sbjct: 185 SPAWSPDG-------SKIAYVTFESGKSALVIQTLANGAIRQVASFPRHNGAPAFSPDGT 237 Query: 111 FVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQEGHKLAYVWKN-- 168 + + S + + + DL Q+ +N +W + LAY Sbjct: 238 KLAFALS------KSGSLNLYVMDLASGQISQVTDGRSNNTEPSWFPDSQNLAYTSDQGG 291 Query: 169 --DIYVKIEPHLPSHRITSTGKEN 190 +Y RIT G +N Sbjct: 292 RPQVYKVNINGGVPQRITWEGSQN 315 Score = 38.7 bits (88), Expect = 0.010, Method: Composition-based stats. Identities = 23/126 (18%), Positives = 38/126 (30%), Gaps = 35/126 (27%) Query: 105 VSPDRL---FVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQEGHK 161 SPD +V E ++ I L + P + +S +G K Sbjct: 188 WSPDGSKIAYVTFESG---------KSALVIQTLANGAIRQVASFPRHNGAPAFSPDGTK 238 Query: 162 LAYVWKN----DIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSALWWSPN 217 LA+ ++YV ++T G+ N + W P+ Sbjct: 239 LAFALSKSGSLNLYVMDLASGQISQVT-DGRSN------------------NTEPSWFPD 279 Query: 218 GTFLAY 223 LAY Sbjct: 280 SQNLAY 285 >4WY8-A nrPDB Length = 327 Score = 39.4 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 48/297 (16%), Positives = 103/297 (34%), Gaps = 48/297 (16%) Query: 501 LDKMLQDVQMPSKKLDFIVLNE---TRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKAD 557 K L+ +P L+ +N ++ + P + P++ G Sbjct: 41 DPKALEG--LPDVYLEEKTINRKNGSKIELTITRPLDTENQVLPPIVFFHGGGWVVGSKL 98 Query: 558 AAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKM 617 R + + + +I ++ S + A+ E+ ++A K Sbjct: 99 THRRTVYELTVRARAAVIFVNY----SLSPEVRFPTAL---------EECLDAVVWVAKE 145 Query: 618 GF-----VDSKRVAIWGWSYGGYVTSMVLGSGSGV----FKCGIAVAPVSRWEYYDSVY- 667 VD ++ + G S GG ++++V + K + + PV+ + Y Sbjct: 146 ENAKSINVDPTKLVVAGDSAGGNLSAVVCIRAKQLGLNIIKGQVLIYPVTDDNFETDSYK 205 Query: 668 --------TERYMG------LPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVH 713 T + M +P +D + + + ++ + + L+ D V Sbjct: 206 QFAENYYLTRKLMVWFFDHYIPDKKDRQSIF-ACPLKASIDDLRVLPRALVITAEAD-VL 263 Query: 714 FQQSAQISKALVDAGVDFQAMWYTDEDHGI----ASSTAHQHIYSHMSHFLQQCFSL 766 ++ ++ L++AG D A+ Y HGI S I H+ +LQ+ + L Sbjct: 264 REEGEAYARKLIEAGNDVTAVRYLGIIHGIFNLATLSPTGSEILDHIVAWLQKTWKL 320 >1Q83-A nrPDB Length = 580 Score = 39.0 bits (89), Expect = 0.007, Method: Composition-based stats. Identities = 27/142 (19%), Positives = 51/142 (35%), Gaps = 9/142 (6%) Query: 527 YQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGY 586 Y + P+ + P+LI +Y G A+ + +LA E ++ S + R + Sbjct: 129 YLNVWTPYPRPASPTPVLIWIYGG-GFYSGAASLDVYDGRFLAQVEGAVLVSMNYRVGTF 187 Query: 587 QGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFV---DSKRVAIWGWSYGGYVTSMVLGS 643 + + G + + DQ A + + D V ++G S G M + S Sbjct: 188 GFLALPGSREAP-GNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILS 246 Query: 644 GS--GVFKCGI--AVAPVSRWE 661 +F + + P W Sbjct: 247 LPSRSLFHRAVLQSGTPNGPWA 268 >2YH2-A nrPDB Length = 313 Score = 39.0 bits (89), Expect = 0.008, Method: Composition-based stats. Identities = 46/235 (19%), Positives = 77/235 (32%), Gaps = 44/235 (18%) Query: 535 FDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHA 594 ++ P ++ + G + + LA+ +V S D R + K A Sbjct: 70 PRDGERLPAVVYYHGGGFVLGSVET-HDHVCRRLANLSGAVVVSVDYRLAPEH--KFPAA 126 Query: 595 INKRLGTLEVEDQIEAARQFL----KMGFVDSKRVAIWGWSYGGYVTS----MVLGSGSG 646 VED +AA+ K+G VD+ ++A+ G S GG + + M G Sbjct: 127 ---------VEDAYDAAKWVADNYDKLG-VDNGKIAVAGDSAGGNLAAVTAIMARDRGES 176 Query: 647 VFKCGIAVAPVSRWEYYDSVYTERYMG------------------LPTPEDNLDHYRNST 688 K + + P +V Y G P+D L Y ++ Sbjct: 177 FVKYQVLIYPAVNLTGSPTVSRVEYSGPEYVILTADLMAWFGRQYFSKPQDALSPY--AS 234 Query: 689 VMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGI 743 + A+ L+I D + + L GV A+ Y HG Sbjct: 235 PIF-ADLSNLPPALVITAEYDP--LRDEGELYAHLLKTRGVRAVAVRYNGVIHGF 286 >1LLF-A nrPDB Length = 534 Score = 39.0 bits (89), Expect = 0.008, Method: Composition-based stats. Identities = 37/183 (20%), Positives = 58/183 (31%), Gaps = 38/183 (20%) Query: 496 EDNSALDKMLQDVQMPSKKLD-FIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAG---- 550 L K D+ M SK + +E ++ PP P+++ ++ G Sbjct: 68 TFEENLGKTALDLVMQSKVFQAVLPQSEDCLTINVVRPPGTKAGANLPVMLWIFGGGFEI 127 Query: 551 ------PCSQKADAA-------FRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINK 597 P +Q + + +AS + GSG G K ++ Sbjct: 128 GSPTIFPPAQMVTKSVLMGKPIIHVAVNYRVASWGFLAGDDIKAEGSGNAGLK-----DQ 182 Query: 598 RLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSG--------VFK 649 RLG V D I D +V I+G S G L G +F+ Sbjct: 183 RLGMQWVADNIAGFG-------GDPSKVTIFGESAGSMSVLCHLIWNDGDNTYKGKPLFR 235 Query: 650 CGI 652 GI Sbjct: 236 AGI 238 >2C7B-A nrPDB Length = 311 Score = 38.7 bits (88), Expect = 0.009, Method: Composition-based stats. Identities = 37/176 (21%), Positives = 65/176 (36%), Gaps = 28/176 (15%) Query: 493 RVLEDNSALDKMLQDVQMPSKKLDFIVLN--ETRFWYQMILPPHFDKSKKYPLLIDVYAG 550 R +E+ S L VQ P + + + ++ P K+ P ++ + G Sbjct: 28 RQVEEQSRLLTA--AVQEPIAETRDVHIPVSGGSIRARVYFP---KKAAGLPAVLYYHGG 82 Query: 551 PCSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEA 610 + + L+ + +V S D R + K A VED A Sbjct: 83 GFVFGSIET-HDHICRRLSRLSDSVVVSVDYRLAPEY--KFPTA---------VEDAYAA 130 Query: 611 ARQFL----KMGFVDSKRVAIWGWSYGGYVTS--MVLGSGSG--VFKCGIAVAPVS 658 + ++G VD R+A+ G S GG + + +L SG + K + + PV Sbjct: 131 LKWVADRADELG-VDPDRIAVAGDSAGGNLAAVVSILDRNSGEKLVKKQVLIYPVV 185 >2JBW-A nrPDB Length = 386 Score = 38.7 bits (88), Expect = 0.010, Method: Composition-based stats. Identities = 35/208 (16%), Positives = 75/208 (36%), Gaps = 23/208 (11%) Query: 511 PSKKLDFIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLAS 570 P + +V++ + +P +P +I + G S K ++ N L Sbjct: 125 PPAERHELVVDGIPMPVYVRIPEGPGP---HPAVIML-GGLESTKEESFQMEN----LVL 176 Query: 571 TENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGW 630 + A+FDG G QG+ KR+ + K+ + + + + G Sbjct: 177 DRGMATATFDGPG---QGEMFE---YKRIAGDYEKYTSAVVDLLTKLEAIRNDAIGVLGR 230 Query: 631 SYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYD-----SVYTERYMGLPTPEDNLDHYR 685 S GG + C I+ S +Y+D + + +Y+ + + Sbjct: 231 SLGGNYALKSAACEPRLAAC-ISWGGFSDLDYWDLETPLTKESWKYVSKVDTLEEARLHV 289 Query: 686 NSTVMSRAENFKQV--EYLLIHGTADDN 711 ++ + +R + Q+ ++HG D+ Sbjct: 290 HAALETR-DVLSQIACPTYILHGVHDEV 316 >4DGQ-A nrPDB Length = 280 Score = 38.3 bits (87), Expect = 0.014, Method: Composition-based stats. Identities = 15/44 (34%), Positives = 19/44 (43%), Gaps = 3/44 (6%) Query: 700 EYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGI 743 L+IHG D V + S +S LV G + Y HGI Sbjct: 222 PVLVIHGDDDQVVPYADSGVLSAKLVKNGK---LITYKGAPHGI 262 >3WMR-A nrPDB Length = 315 Score = 37.5 bits (85), Expect = 0.020, Method: Composition-based stats. Identities = 29/154 (18%), Positives = 56/154 (36%), Gaps = 15/154 (9%) Query: 506 QDVQMPSKKLDFIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWA 565 + + P + + R WY++ H S K P+++ + GP S A Sbjct: 15 RHMSKPPSAKGTVPFGQYRTWYRVTGDLH---SGKPPVVLL-HGGPGSTH-----DYLLA 65 Query: 566 TYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRV 625 + V +D G+G + ED+++ ++G + Sbjct: 66 MTSLTEAGWPVVHYDQLGNGGS-THLPEKGEDFWTVQLFEDELDNL--LNQLGI--AGDY 120 Query: 626 AIWGWSYGGYVTSMVLGSGS-GVFKCGIAVAPVS 658 ++G S+GG + S+ G+ +A AP S Sbjct: 121 VLFGQSWGGMLGSVHAARRPAGLRGLVVANAPAS 154 >1R88-A nrPDB Length = 280 Score = 37.1 bits (84), Expect = 0.026, Method: Composition-based stats. Identities = 25/136 (18%), Positives = 41/136 (30%), Gaps = 19/136 (13%) Query: 526 WYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFR-----LNWATY---LASTENIIVA 577 Y+ ++ P + P+ GP + AF NW T + + ++ Sbjct: 10 PYENLMVPSPSMGRDIPVAFLA-GGPHAVYLLDAFNAGPDVSNWVTAGNAMNTLAGKGIS 68 Query: 578 SFDGRGSGYQG-DKIMHAINKRLGTL---EVEDQIEAARQFLKMGFVDSKRVAIWGWSYG 633 G Y +K+ T E+ D + A R G A G + G Sbjct: 69 VVAPAGGAYSMYTNWEQDGSKQWDTFLSAELPDWLAANRGLAPGGH------AAVGAAQG 122 Query: 634 GYVTSMVLGSGSGVFK 649 GY + F Sbjct: 123 GYGAMALAAFHPDRFG 138 >1MPX-A nrPDB Length = 615 Score = 37.1 bits (84), Expect = 0.030, Method: Composition-based stats. Identities = 28/159 (17%), Positives = 60/159 (37%), Gaps = 14/159 (8%) Query: 512 SKKLDFIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLAST 571 +++ + + + ++LP +K P+++ S + + + L++ Sbjct: 25 KREVMIPMRDGVKLHTVIVLP---KGAKNAPIVLTRTPYDASGRTERLASPHMKDLLSAG 81 Query: 572 E------NIIVASFDGRGS-GYQGDKIM-HAINKRLGTLEVE---DQIEAARQFLKMGFV 620 + I D RG G +GD +M + L EV+ D + +K Sbjct: 82 DDVFVEGGYIRVFQDVRGKYGSEGDYVMTRPLRGPLNPSEVDHATDAWDTIDWLVKNVSE 141 Query: 621 DSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSR 659 + +V + G SY G+ M L + K + +P+ Sbjct: 142 SNGKVGMIGSSYEGFTVVMALTNPHPALKVAVPESPMID 180 >5L2P-A nrPDB Length = 306 Score = 36.7 bits (83), Expect = 0.040, Method: Composition-based stats. Identities = 35/181 (19%), Positives = 60/181 (33%), Gaps = 24/181 (13%) Query: 498 NSALDKMLQDVQMPSKKLDFIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKAD 557 N L K + + + I L + ++ P + L++ + G Sbjct: 35 NELLAKAVPKDPVGETRDMKIKLEDYELPIRIYSPIKRTNNG---LVMHFHGG-AWILGS 90 Query: 558 AAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFL-- 615 + L+++ V S D R + K A+ D A Sbjct: 91 IETEDAISRILSNSCECTVISVDYRLAPEY--KFPTAVY---------DCFNAIVWARDN 139 Query: 616 --KMGFVDSKRVAIWGWSYGG-YVTSMVLGSGSGVFKCGIAVAPVSRWEYYD--SVYTER 670 ++G +D ++A +G S GG V + L + K A PV + Y D S R Sbjct: 140 AGELG-IDKDKIATFGISAGGNLVAATSLLARDNKLKL-TAQVPVVPFVYLDLASKSMNR 197 Query: 671 Y 671 Y Sbjct: 198 Y 198 >3FNB-A nrPDB Length = 405 Score = 36.7 bits (83), Expect = 0.041, Method: Composition-based stats. Identities = 37/180 (20%), Positives = 66/180 (36%), Gaps = 29/180 (16%) Query: 487 TDQKELRVLEDNSALDK----MLQDVQMPSKKLDFIVLNETRFWYQMILPPHFDKSKKYP 542 TD K+ +E+ ++K + + ++P K ++ E Y +I + K Sbjct: 106 TDPKDSEFMENFRRMEKLFMLAVDNSKIPLKSIEVPFEGELLPGYAII-----SEDKAQD 160 Query: 543 LLIDVYAGPCSQKADAAF--RLNWATYLASTENIIVASFDGRG-SGYQGDKIMHAINKRL 599 LI V G S++ W N+++ G+G + QG Sbjct: 161 TLIVVGGGDTSREDLFYMLGYSGWEH----DYNVLMVDLPGQGKNPNQGLHFE------- 209 Query: 600 GTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSR 659 D A L ++++AI G+S GGY T+ + + K IA P+ Sbjct: 210 -----VDARAAISAILDWYQAPTEKIAIAGFSGGGYFTAQAVEKDKRI-KAWIASTPIYD 263 >5K1H-B nrPDB Length = 576 Score = 36.4 bits (82), Expect = 0.052, Method: Composition-based stats. Identities = 33/179 (18%), Positives = 62/179 (34%), Gaps = 32/179 (17%) Query: 58 LRWVSDSEYL--YKQENNILLFNAEHGNSSIFLENSTFEIFGDSISDYSVSPDRLFVLLE 115 +RW YL + Q I L+ E F + F G + D+ SP +++ Sbjct: 171 VRWSPKGTYLATFHQRG-IALWGGEK-----FKQIQRFSHQGVQLIDF--SPCERYLVTF 222 Query: 116 YNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWI--TWSQEGHKLAYVWKNDIYVK 173 + + I+D+ ++ W WS +G A + + + + Sbjct: 223 SPLMDT--QDDPQAIIIWDILTGHKKRGFHCESSAHWPIFKWSHDGKFFARMTLDTLSIY 280 Query: 174 IEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSALWWSPNGTFLAYAQFNDTGVP 232 P + K+++ +GI D+ WSP G +A+ D +P Sbjct: 281 ETPSMGLLD-----KKSLKISGIKDF-------------SWSPGGNIIAFWVPEDKDIP 321 >1UFO-A nrPDB Length = 238 Score = 36.0 bits (81), Expect = 0.065, Method: Composition-based stats. Identities = 26/150 (17%), Positives = 47/150 (31%), Gaps = 25/150 (16%) Query: 625 VAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPED-NLDH 683 + + G S G +V ++L G F+ P + S + + ED + Sbjct: 107 LFLAGGSLGAFVAHLLLAEG---FR------PRGVLAFIGSGFPMKLPQGQVVEDPGVLA 157 Query: 684 YRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQ------AMWYT 737 + +R E + V L +HG+ D V + + +AL Sbjct: 158 LYQAPPATRGEAYGGVPLLHLHGSRDHIVPLARMEKTLEAL----RPHYPEGRLARFVEE 213 Query: 738 DEDHGIASSTAHQHIYSHMSHFLQQCFSLR 767 H + A + FL+ R Sbjct: 214 GAGHTLTPLMARVGL-----AFLEHWLEAR 238 >1LNS-A nrPDB Length = 763 Score = 36.0 bits (81), Expect = 0.070, Method: Composition-based stats. Identities = 40/241 (16%), Positives = 69/241 (28%), Gaps = 68/241 (28%) Query: 555 KADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQF 614 ++ F+ + + ++ +GR Y K H I Sbjct: 293 RSSDGFQTSGDYQQIYSMTAVIDWLNGRARAYTSRKKTHEIKASWANG------------ 340 Query: 615 LKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYY----------- 663 +VA+ G SY G + +G + +A A +S W Y Sbjct: 341 ---------KVAMTGKSYLGTMAYGAATTGVEGLELILAEAGISSWYNYYRENGLVRSPG 391 Query: 664 -----------DSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEY----------- 701 Y+ G + N ++ + M+ A + K +Y Sbjct: 392 GFPGEDLDVLAALTYSRNLDGADFLKGNAEYEKRLAEMTAALDRKSGDYNQFWHDRNYLI 451 Query: 702 ---------LLIHGTADDNVHFQQSAQISKALVDAGVDFQ-----AMWYTDEDHGIASST 747 L++HG D NV +Q+ KAL + A Y + I S Sbjct: 452 NTDKVKADVLIVHGLQDWNVTPEQAYNFWKALPEGHAKHAFLHRGAHIYMNSWQSIDFSE 511 Query: 748 A 748 Sbjct: 512 T 512 >1GZ7-A nrPDB Length = 534 Score = 35.6 bits (80), Expect = 0.076, Method: Composition-based stats. Identities = 34/182 (18%), Positives = 56/182 (30%), Gaps = 38/182 (20%) Query: 497 DNSALDKMLQDVQMPSKKLDFIVLNETR-FWYQMILPPHFDKSKKYPLLIDVYAG----- 550 L K D+ + SK ++ N+ +I PP S P+++ ++ G Sbjct: 69 FEDTLPKNALDLVLQSKIFQVVLPNDEDCLTINVIRPPGTRASAGLPVMLWIFGGGFELG 128 Query: 551 -----PCSQKADA-------AFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKR 598 P Q ++ +AS + GSG G + + Sbjct: 129 GSSLFPGDQMVAKSVLMGKPVIHVSMNYRVASWGFLAGPDIQNEGSGNAGLH-DQRLAMQ 187 Query: 599 LGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSG--------VFKC 650 V D I D +V I+G S G T + L G +F+ Sbjct: 188 W----VADNIAGFG-------GDPSKVTIYGESAGSMSTFVHLVWNDGDNTYNGKPLFRA 236 Query: 651 GI 652 I Sbjct: 237 AI 238 >4HZN-A nrPDB Length = 333 Score = 35.6 bits (80), Expect = 0.077, Method: Composition-based stats. Identities = 27/159 (16%), Positives = 47/159 (29%), Gaps = 21/159 (13%) Query: 550 GPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIE 609 GP S W T A + + A+ D G+ + Sbjct: 39 GPGSLFVGQLGDWTWETVSAQCDTDVFAARDASGNPTYLAFYYFRVR------------- 85 Query: 610 AARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYD----- 664 R+ R+ + Y S++ A P+ E+Y+ Sbjct: 86 GGRELHPGSLTFGDRLTVTSGCYDQGTESVLTLHRIDRAGSDDAQRPLDLHEFYERPRDG 145 Query: 665 SVYTE---RYMGLPTPEDNLDHYRNSTVMSRAENFKQVE 700 S+Y E R++ P N D ++S R + Q+ Sbjct: 146 SLYVENFNRWVTRSAPGSNEDLVKSSPPGFRNDGLPQLP 184 >6EIC-C nrPDB Length = 279 Score = 34.8 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 37/288 (12%), Positives = 87/288 (30%), Gaps = 56/288 (19%) Query: 514 KLDFIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTEN 573 + +F + + R Y + P ++ +++ + + A R + Sbjct: 7 ERNFAGIGDVRIVYDVWTPDTAPQA----VVVLAHG-----LGEHARRYDHVAQRLGAAG 57 Query: 574 IIVASFDGRGSGYQGDKIMHAINKRLGTLEVE-DQIEAARQFLKMGFVDSKRVAIWGWSY 632 ++ + D RG G G K + + + + D + + KR+ + G S Sbjct: 58 LVTYALDHRGHGRSGGK--RVLVRDISEYTADFDTLVGIAT---REYPGCKRI-VLGHSM 111 Query: 633 GGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDS---VYTERYMGLPTP------------ 677 GG + + + AP + S + +G+ P Sbjct: 112 GGGIVFAYGVERPDNYDLMVLSAPAVAAQDLVSPVVAVAAKLLGVVVPGLPVQELDFTAI 171 Query: 678 EDNLDHYR--NSTVMSRAENFKQV---------------------EYLLIHGTADDNVHF 714 + + + N+ + L++HGT D + Sbjct: 172 SRDPEVVQAYNTDPLVHHGRVPAGIGRALLQVGETMPRRAPALTAPLLVLHGTDDRLIPI 231 Query: 715 QQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFLQQ 762 + S ++ + + A D Q Y H + + + + +L + Sbjct: 232 EGSRRLVECVGSA--DVQLKEYPGLYHEVFNEPERNQVLDDVVAWLTE 277 >5LZ5-A nrPDB Length = 388 Score = 34.8 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 14/43 (32%), Positives = 23/43 (53%), Gaps = 4/43 (9%) Query: 620 VDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEY 662 +D +++A+ G S+GG L S F+CGIA+ W + Sbjct: 217 IDREKIAVIGHSFGGATVIQTL-SEDQRFRCGIAL---DAWMF 255 >3N0T-A nrPDB Length = 469 Score = 34.8 bits (78), Expect = 0.15, Method: Composition-based stats. Identities = 23/97 (23%), Positives = 42/97 (43%), Gaps = 8/97 (8%) Query: 568 LASTENIIVASFDGRGSGYQ---GDKIMHAINKRLGTLE--VEDQIEAARQFLK-MGFVD 621 LA+ ++ + R G G + + L T+E + D E R + +G D Sbjct: 71 LAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQD 130 Query: 622 SKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAV-APV 657 + +A +G SYGG +++ + + +A APV Sbjct: 131 APAIA-FGGSYGGMLSAYLRMKYPHLVAGALAASAPV 166 >1NX9-A nrPDB Length = 652 Score = 34.8 bits (78), Expect = 0.15, Method: Composition-based stats. Identities = 40/196 (20%), Positives = 60/196 (30%), Gaps = 36/196 (18%) Query: 572 ENIIVASFDGRGS-GYQGDKIM----HAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVA 626 I D RG G QGD +M H T E D + + + RV Sbjct: 101 GGYIRVFQDIRGKYGSQGDYVMTRPPHGPLNPTKTDETTDAWDTVDWLVHNVPESNGRVG 160 Query: 627 IWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSR-----------------WEYYDSVYTE 669 + G +Y G+ M L K +P+ ++Y+ S T Sbjct: 161 MTGSAYEGFTVVMALLDPHPALKVAAPESPMVDGWMGDDWFHYGAFRQGAFDYFVSQMTA 220 Query: 670 RYMGLPTPEDNLDHYRN-------STVMSRAENFKQVEY---LLIHGTADDNVHFQQSAQ 719 R G P + D Y N + ++A Q + + H D F Q Sbjct: 221 RGGGNDIPRRDADDYTNFLKAGSAGSFATQA-GLDQYPFWQRMHAHPAYDA---FWQGQA 276 Query: 720 ISKALVDAGVDFQAMW 735 + K L +W Sbjct: 277 LDKILAQRKPTVPMLW 292 >3WLA-A nrPDB Length = 336 Score = 34.4 bits (77), Expect = 0.17, Method: Composition-based stats. Identities = 26/112 (23%), Positives = 39/112 (34%), Gaps = 15/112 (13%) Query: 580 DGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSM 639 DGR GDK + LE + + L D KR+ + G S GG +T+ Sbjct: 116 DGRAPDASGDKYKTDAGDDVRFLEAMVRCVGTKWKL-----DRKRLFLGGISAGGTMTNR 170 Query: 640 VLGSGSGVFKCGIAVAPVSR-WEYYDSVYTERYMGLPTPEDNLDHYRNSTVM 690 L S + G+ P+S W Y+ + G P + Sbjct: 171 ALLFDSEFWAGGM---PISGEW------YSTKDDGSTVPFQETRKMVAAAPA 213 >1AZW-A nrPDB Length = 313 Score = 34.4 bits (77), Expect = 0.19, Method: Composition-based stats. Identities = 36/313 (11%), Positives = 73/313 (23%), Gaps = 96/313 (30%) Query: 511 PSKKLDFIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLAS 570 P ++ V + +++ PH ++ ++ GP D R + Sbjct: 10 PYQQGSLKVDDRHTLYFEQCGNPHGKP------VVMLHGGPGGGCNDKMRRFH------D 57 Query: 571 TENIIVASFDGRGSGYQ-------------------------GDKIMHAINKRLG----- 600 + FD RGSG G G Sbjct: 58 PAKYRIVLFDQRGSGRSTPHADLVDNTTWDLVADIERLRTHLGVDRWQVFGGSWGSTLAL 117 Query: 601 -------TLEVEDQIEAA--------RQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGS 645 E + F + G + R+ W + Y+ ++ + Sbjct: 118 AYAQTHPQQVTELVLRGIFLLRRFELEWFYQEG---ASRLFPDAWEH--YLNAIPPVERA 172 Query: 646 GVFKC----------GIAVAPVSRWEYYDSVYTERYMGLP------------TPEDNLDH 683 + +A W ++ + ++ +H Sbjct: 173 DLMSAFHRRLTSDDEATRLAAAKAWSVWEGATSFLHVDEDFVTGHEDAHFALAFARIENH 232 Query: 684 Y--------RNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMW 735 Y ++ A + +++HG D Q + + KA A Q Sbjct: 233 YFVNGGFFEVEDQLLRDAHRIADIPGVIVHGRYDVVCPLQSAWDLHKAWPKA----QLQI 288 Query: 736 YTDEDHGIASSTA 748 H Sbjct: 289 SPASGHSAFEPEN 301 >4G5X-A nrPDB Length = 279 Score = 34.0 bits (76), Expect = 0.24, Method: Composition-based stats. Identities = 24/143 (16%), Positives = 46/143 (32%), Gaps = 17/143 (11%) Query: 569 ASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDS-----K 623 +S+ I +G G K G + D I+ R + G+ D+ + Sbjct: 34 SSSGAIFAPQLEG----EIGKKWRVIAPDLPGHGKSTDAIDPDRSYSMEGYADAMTEVMQ 89 Query: 624 RVAI-----WGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPE 678 ++ I +GWS GG++ ++ + I P E + G Sbjct: 90 QLGIADAVVFGWSLGGHIGIEMIARYPEMRGLMITGTPPVAREEVGQGFKS---GPDMAL 146 Query: 679 DNLDHYRNSTVMSRAENFKQVEY 701 + + V S A + + Sbjct: 147 AGQEIFSERDVESYARSTCGEPF 169 >1DIN-A nrPDB Length = 236 Score = 34.0 bits (76), Expect = 0.24, Method: Composition-based stats. Identities = 29/164 (17%), Positives = 53/164 (32%), Gaps = 37/164 (22%) Query: 586 YQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGS 645 Q K+ A + G ++E A R + + +V + G+ GG + +V G Sbjct: 82 EQAYKLWQAFDMEAGVGDLE---AAIRYARHQPYSN-GKVGLVGYCLGGALAFLVAAKG- 136 Query: 646 GVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEY-LLI 704 Y +R +G Y + + +V++ L Sbjct: 137 ---------------------YVDRAVG----------YYGVGLEKQLNKVPEVKHPALF 165 Query: 705 HGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTA 748 H D+ S Q+ A Q WY + H A +++ Sbjct: 166 HMGGQDHFVPAPSRQLITEGFGANPLLQVHWYEEAGHSFARTSS 209 >6EMI-A nrPDB Length = 532 Score = 34.0 bits (76), Expect = 0.24, Method: Composition-based stats. Identities = 34/168 (20%), Positives = 58/168 (34%), Gaps = 14/168 (8%) Query: 499 SALDKMLQDVQMPSKKLDFIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADA 558 +D L+E + + +P K K +++ +Y G Q + Sbjct: 70 QNIDTSFPGFHGSEMWNPNTDLSEDCLYLNVWIPA--PKPKNATVMVWIYGG-GFQTGTS 126 Query: 559 AFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMG 618 + + +LA E +IV S + R + G + + DQ A + Sbjct: 127 SLPVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAP-GNMGLFDQQLALKWVQDNI 185 Query: 619 FV---DSKRVAIWGWSYGGYVTSMVL---GSGS----GVFKCGIAVAP 656 D RV ++G S G S+ L GS + + G A AP Sbjct: 186 AAFGGDPNRVTLFGESAGAASVSLHLLSPGSHPLFTRAILQSGSANAP 233 >1ODT-C nrPDB Length = 318 Score = 34.0 bits (76), Expect = 0.26, Method: Composition-based stats. Identities = 45/266 (16%), Positives = 79/266 (29%), Gaps = 46/266 (17%) Query: 526 WYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSG 585 WY + DK +P ++ + S + +NW + RG Sbjct: 72 WYAV-----PDKEGPHPAIVKYHGYNASYDGEIHEMVNW-----ALHGYATFGMLVRGQQ 121 Query: 586 YQGDKI-----MHAINKRLGTLEVE---------DQIEAARQFLKMGFVDSKRVAIWGWS 631 D G L+ + D + A VD R+ + G + Sbjct: 122 SSEDTSISPHGHALGWMTKGILDKDTYYYRGVYLDAVRALEVISSFDEVDETRIGVTGGA 181 Query: 632 YGGYVTSMVLGSGSGVFKCGIAVAP-VSRWEY-YDSVYTERYMGLPTPEDNLDHYRNSTV 689 GG +T + S + K +A P +S +E D E Y+ + + RN + Sbjct: 182 QGGGLTIAA-AALSDIPKAAVADYPYLSNFERAIDVALEEPYLEINSFFR-----RNGSP 235 Query: 690 MSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAH 749 + + K + Y I AD +S L+D + +H Sbjct: 236 ETEVQAMKTLSYFDIMNLADRVKVP---VLMSIGLIDKVTPPST-VFAAYNHLETKKELK 291 Query: 750 QHIY----------SHMSHFLQQCFS 765 + Y + F +Q Sbjct: 292 VYRYFGHEYIPAFQTEKLAFFKQHLK 317 >5HQ3-A nrPDB Length = 548 Score = 34.0 bits (76), Expect = 0.27, Method: Composition-based stats. Identities = 29/143 (20%), Positives = 55/143 (38%), Gaps = 9/143 (6%) Query: 527 YQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVASFDGRGSGY 586 Y + P+ P+++ +Y G ++ + +L TE +++ S + R + Sbjct: 99 YLNVWTPYPRPKNPAPVMVWIYGG-GFYSGSSSLDVYDGRFLVRTERVVLVSMNYRVGAF 157 Query: 587 QGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFV---DSKRVAIWGWSYGGYVTSMVLGS 643 + + G + + DQ A + + D V ++G S G M L S Sbjct: 158 GFLALPGSREAP-GNVGLLDQRLALQWVQENIAAFGGDPTSVTLFGESAGAASVGMHLLS 216 Query: 644 GS--GVFKCGI--AVAPVSRWEY 662 G+F I + AP + W Y Sbjct: 217 PPSRGLFHRAILQSGAPNAPWAY 239 >1BU8-A nrPDB Length = 452 Score = 33.7 bits (75), Expect = 0.34, Method: Composition-based stats. Identities = 19/106 (17%), Positives = 38/106 (35%), Gaps = 1/106 (0%) Query: 102 DYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQEGHK 161 Y VS Y+ + + Y++ K L E + + E K Sbjct: 341 RYKVSVTLSGAKKLSGYILVALYGNNGNSKQYEIFKGSLKPEARHVRDIDVDINVGEIQK 400 Query: 162 LAYVWKNDIYVKIEPHLPSHRITS-TGKENVIFNGINDWVYEEEIF 206 + ++W N + P L + +IT +G + +N + E++ Sbjct: 401 VKFLWNNKVINLFRPTLGASQITVQSGVDGKEYNFCSSDTVREDVL 446 >1HPL-A nrPDB Length = 449 Score = 33.7 bits (75), Expect = 0.36, Method: Composition-based stats. Identities = 12/74 (16%), Positives = 31/74 (41%) Query: 133 YDLNKRQLITEEKIPNNTQWITWSQEGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVI 192 Y++ + L + N + K+ ++W N++ P + + +IT + + Sbjct: 370 YEIFQGTLKPDNTYSNEFDSDVEVGDLEKVKFIWYNNVINLTLPKVGASKITVERNDGSV 429 Query: 193 FNGINDWVYEEEIF 206 FN ++ E++ Sbjct: 430 FNFCSEETVREDVL 443 >6AGQ-A nrPDB Length = 321 Score = 33.3 bits (74), Expect = 0.38, Method: Composition-based stats. Identities = 34/176 (19%), Positives = 51/176 (28%), Gaps = 37/176 (21%) Query: 606 DQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLG--SGSGV----------FKCGI- 652 D I A VD+ R+A++G S GG + G S + F+ + Sbjct: 160 DCIRALDFVCSREEVDASRIAVYGGSQGGGLALAAAGLDSRPKLALPVFPFLCHFRRSVE 219 Query: 653 --AVAPVSRWEYYDSVYTERYMGLPTPEDNLDH--YRNSTV---MSRAENFKQVEYLLIH 705 A P + + RY PE + YR + M+ A K + I Sbjct: 220 IHASGPYVEIK----NWFRRY----DPEHRQEEQVYRTLSYFDGMNMASRIKARTLMAI- 270 Query: 706 GTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFLQ 761 D L + Y D H H M F++ Sbjct: 271 TLQDITCPPSTCFAAYNHLAG---PKEVRLYHDYGH----EGLPFH-EEAMMRFIE 318 >3FM0-A nrPDB Length = 345 Score = 33.3 bits (74), Expect = 0.43, Method: Composition-based stats. Identities = 24/129 (18%), Positives = 43/129 (33%), Gaps = 28/129 (21%) Query: 105 VSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQ---LITEEKIPNNTQWITWSQEGHK 161 SP ++ S+ A+ I+ N+ + T E N + + W+ G+ Sbjct: 69 WSPCGNYL---------ASASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNL 119 Query: 162 LAYV-WKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSALWWSPNGTF 220 LA ++V + S + N V + W P+ Sbjct: 120 LATCSRDKSVWVWEVDEEDEYECVS------VLNSHTQDV---------KHVVWHPSQEL 164 Query: 221 LAYAQFNDT 229 LA A ++DT Sbjct: 165 LASASYDDT 173 >2PPL-A nrPDB Length = 485 Score = 32.9 bits (73), Expect = 0.49, Method: Composition-based stats. Identities = 13/93 (13%), Positives = 31/93 (33%), Gaps = 1/93 (1%) Query: 115 EYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQEGHKLAYVWKNDIYVKI 174 +K + Y + + L K+ ++W N++ Sbjct: 377 ATGQIKVALFGNKGNTHQYSIFRGILKPGSTHSYEFDAKLDVGTIDKVKFLWNNNVINPT 436 Query: 175 EPHLPSHRITST-GKENVIFNGINDWVYEEEIF 206 P + + +IT G+E ++N ++ E+ Sbjct: 437 LPKVGATKITVQKGEEKTVYNFCSEDTVREDTL 469 >5W8P-A nrPDB Length = 370 Score = 32.9 bits (73), Expect = 0.50, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 27/79 (34%), Gaps = 9/79 (11%) Query: 582 RGSGYQGDKIMHAINKRLG----TLEVEDQIEA-ARQFLKMGFVDSKRVAIWGWSYGGYV 636 RG+ G + K G + V DQ+ A ++G + A+ G S GG Sbjct: 101 RGTT--GPTSLARDGKPWGSRFPEVSVRDQVNADVAALAQLGITEVA--AVVGGSMGGAR 156 Query: 637 TSMVLGSGSGVFKCGIAVA 655 + + +A Sbjct: 157 ALEWAVMHPDAVRAALVLA 175 >1RP1-A nrPDB Length = 450 Score = 32.9 bits (73), Expect = 0.55, Method: Composition-based stats. Identities = 13/93 (13%), Positives = 32/93 (34%), Gaps = 1/93 (1%) Query: 115 EYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQEGHKLAYVWKNDIYVKI 174 K + +++ K L N K+ ++W N++ Sbjct: 352 ATGQAKVALFGSKGNTHQFNIFKGILKPGSTHSNEFDAKLDVGTIEKVKFLWNNNVVNPT 411 Query: 175 EPHLPSHRITST-GKENVIFNGINDWVYEEEIF 206 P + + +IT G+E + + ++ E++ Sbjct: 412 FPKVGAAKITVQKGEEKTVHSFCSESTVREDVL 444 >3FOB-A nrPDB Length = 281 Score = 32.9 bits (73), Expect = 0.56, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 27/65 (41%), Gaps = 4/65 (6%) Query: 698 QVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMS 757 + L+IHG +D V F+ S +++ + HG+ ++ A + + Sbjct: 221 NIPTLIIHGDSDATVPFEYSGKLTHEAIPNSK---VALIKGGPHGLNATHAKE-FNEALL 276 Query: 758 HFLQQ 762 FL+ Sbjct: 277 LFLKD 281 >5XMC-A nrPDB Length = 722 Score = 32.9 bits (73), Expect = 0.60, Method: Composition-based stats. Identities = 21/134 (15%), Positives = 40/134 (29%), Gaps = 14/134 (10%) Query: 258 GAVNPTVKFFIVNTDSLSSTTTTIPMQITAPASVTTGD-----HYL----CDVAWVSEDR 308 GA + + ++ S T+ P D +Y+ W + Sbjct: 119 GATSGLIIPLTISGGSGPRPLNTVSQAPLPPGWEQRVDQHGRVYYVDHVEKRTTWDRPEP 178 Query: 309 ISLQWLRRIQNYSVMAICDYDKTTLVWNCPTTQ-----EHIETSATGWCGRFRPAEPHFT 363 + W RR+ N + D+ T W PT + E + + G + F Sbjct: 179 LPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFI 238 Query: 364 SDGSSFYKIVSDKD 377 + +K+ Sbjct: 239 YGNQDLFATSQNKE 252 >4ZWN-A nrPDB Length = 334 Score = 32.5 bits (72), Expect = 0.65, Method: Composition-based stats. Identities = 13/83 (15%), Positives = 24/83 (28%), Gaps = 2/83 (2%) Query: 666 VYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALV 725 +Y + Y+N + K +++HG D + S + + Sbjct: 229 LYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIRDCP 288 Query: 726 DAGVDFQAMWYTDEDHGIASSTA 748 A + Y H I S Sbjct: 289 SADK--ELKLYPGARHSIFSLET 309 >3GBG-A nrPDB Length = 276 Score = 32.5 bits (72), Expect = 0.79, Method: Composition-based stats. Identities = 24/142 (16%), Positives = 53/142 (37%), Gaps = 17/142 (11%) Query: 25 VVLLNKDEAAADSRRTYTLADYLKNTFRVKSYSLRWVSDS-------EYLYKQENNILLF 77 ++LL K+ S + + + + + +R + LY + ++LL+ Sbjct: 58 IILLKKNSIQRFSLTSLSDENINVSVITISDSFIRSLKSYILGDLMIRNLYSENKDLLLW 117 Query: 78 NAEHGNSSIFLENSTFEIFGDSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNK 137 N EH + ++ E + G +YS D + + + Y + + DL+ Sbjct: 118 NCEHNDIAVLSE----VVNGFREINYS---DEFLKVFFSGFFSKVEKKYNSIFITDDLDA 170 Query: 138 RQLIT---EEKIPNNTQWITWS 156 + I+ + I N +W Sbjct: 171 MEKISCLVKSDITRNWRWADIC 192 >6QAA-A nrPDB Length = 557 Score = 32.1 bits (71), Expect = 0.89, Method: Composition-based stats. Identities = 37/178 (20%), Positives = 64/178 (35%), Gaps = 14/178 (7%) Query: 499 SALDKMLQDVQMPSKKLDFIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADA 558 +D+ L+E + + +P K K +LI +Y G Q + Sbjct: 95 QNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPA--PKPKNATVLIWIYGG-GFQTGTS 151 Query: 559 AFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMG 618 + + +LA E +IV S + R + G + + DQ A + K Sbjct: 152 SLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAP-GNMGLFDQQLALQWVQKNI 210 Query: 619 FV---DSKRVAIWGWSYGGYVTSMVL---GSGS----GVFKCGIAVAPVSRWEYYDSV 666 + K V ++G S G S+ L GS S + + G AP + Y++ Sbjct: 211 AAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEAR 268 >5CXX-A nrPDB Length = 275 Score = 32.1 bits (71), Expect = 0.90, Method: Composition-based stats. Identities = 13/46 (28%), Positives = 25/46 (54%), Gaps = 2/46 (4%) Query: 506 QDVQMP--SKKLDFIVLNETRFWYQMILPPHFDKSKKYPLLIDVYA 549 + V+ P K + + ET +ILP +D++KKYP++ ++ Sbjct: 19 EGVEYPTAKKITYYSKVTETERKMNVILPVGYDENKKYPVVYYLHG 64 >5THM-A nrPDB Length = 533 Score = 31.7 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 18/112 (16%), Positives = 36/112 (32%), Gaps = 16/112 (14%) Query: 530 ILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWAT---YLASTENIIVASFDGRGSGY 586 + P K +P++ ++ G F W + I+ R Sbjct: 99 VYKPKNSKRNSFPVVAHIHGGAF------MFGAAWQNGHENVMREGKFILVKISYRLGP- 151 Query: 587 QGDKIMHAINKRL-GTLEVEDQIEAARQFLK---MGFVDSKRVAIWGWSYGG 634 + ++ L G ++DQ A + + + + V + G S GG Sbjct: 152 --LGFLSTGDRDLPGNYGLKDQRLALKWIKQNIASFGGEPQNVLLVGHSAGG 201 >3MGA-A nrPDB Length = 407 Score = 31.0 bits (68), Expect = 2.2, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 22/60 (36%), Gaps = 4/60 (6%) Query: 601 TLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRW 660 E+ Q+ A F D+ R + G S+GG + F C ++ + W Sbjct: 263 QQELLPQVRAVTPFSD----DAGRTVVAGQSFGGLSALYAGLNWPTRFGCVLSQSGSFWW 318 >2E3J-A nrPDB Length = 356 Score = 30.6 bits (67), Expect = 2.5, Method: Composition-based stats. Identities = 10/67 (14%), Positives = 22/67 (32%), Gaps = 9/67 (13%) Query: 533 PHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYL--ASTENIIVASFDGRGSGYQGDK 590 ++ PL++ ++ P S +W + + V + D RG G Sbjct: 19 ADSPPDQQGPLVVLLHGFPES-------WYSWRHQIPALAGAGYRVVAIDQRGYGRSSKY 71 Query: 591 IMHAINK 597 + + Sbjct: 72 RVQKAYR 78 >2B20-A nrPDB Length = 403 Score = 30.6 bits (67), Expect = 2.5, Method: Composition-based stats. Identities = 10/44 (22%), Positives = 15/44 (34%), Gaps = 1/44 (2%) Query: 618 GFVDSK-RVAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRW 660 F D R + G S+GG F C ++ + W Sbjct: 270 PFSDRADRTVVAGQSFGGLSALYAGLHWPERFGCVLSQSGSYWW 313 >4YB9-D nrPDB Length = 479 Score = 30.6 bits (67), Expect = 2.8, Method: Composition-based stats. Identities = 15/41 (36%), Positives = 25/41 (60%), Gaps = 8/41 (19%) Query: 5 WKVLLGLLGVAALVTIITVP--------VVLLNKDEAAADS 37 W +LLGL G+ A++ ++ +P +++ KDEAAA S Sbjct: 192 WPILLGLTGIPAVLQLLFLPFFPESPRYLLIQKKDEAAAKS 232 >3NC3-A nrPDB Length = 441 Score = 30.2 bits (66), Expect = 3.2, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 23/54 (42%), Gaps = 1/54 (1%) Query: 656 PVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLL-IHGTA 708 PV E DS + RY + + D + +++ RAE + L +HG Sbjct: 67 PVHYEESIDSYFISRYHDVRYILQHPDIFTTKSLVERAEPVMRGPVLAQMHGKE 120 >5MP7-A nrPDB Length = 326 Score = 29.8 bits (65), Expect = 4.9, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 24/70 (34%), Gaps = 5/70 (7%) Query: 659 RWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQ-QS 717 Y Y + M + +P+ R A++ V IH T D V Q +S Sbjct: 159 LTGYIGEHYADEDMVVVSPDSG----RVRVAEKWADSLGGVPLAFIHKTRDPLVPNQVKS 214 Query: 718 AQISKALVDA 727 ++ + Sbjct: 215 NRVVGDVKGK 224 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.120 0.304 Lambda K H 0.267 0.0369 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 26,791,500 Number of Sequences: 36641 Number of extensions: 1025571 Number of successful extensions: 3240 Number of sequences better than 10.0: 129 Number of HSP's better than 10.0 without gapping: 81 Number of HSP's successfully gapped in prelim test: 90 Number of HSP's that attempted gapping in prelim test: 2877 Number of HSP's gapped (non-prelim): 210 length of query: 767 length of database: 10,336,785 effective HSP length: 105 effective length of query: 662 effective length of database: 6,489,480 effective search space: 4296035760 effective search space used: 4296035760 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 63 (29.0 bits)