BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P14604 (290 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2DUB-A nrPDB 536 e-153 2HW5-A nrPDB 498 e-141 3H81-A nrPDB 276 9e-75 3MOY-A nrPDB 261 4e-70 4FZW-A nrPDB 235 2e-62 5ZAI-A nrPDB 223 5e-59 5Z7R-A nrPDB 198 3e-51 5JBW-A nrPDB 146 1e-35 2PPY-A nrPDB 137 5e-33 5WYB-B nrPDB 121 4e-28 4JWV-A nrPDB 120 5e-28 2IEX-A nrPDB 120 5e-28 5VE2-A nrPDB 120 6e-28 1EF9-A nrPDB 117 4e-27 5KJP-A nrPDB 116 1e-26 2VSU-C nrPDB 116 1e-26 3T88-A nrPDB 115 2e-26 4EML-A nrPDB 111 3e-25 6OJM-A nrPDB 111 5e-25 2UZF-A nrPDB 110 5e-25 1NZY-B nrPDB 107 5e-24 5YLO-A nrPDB 107 5e-24 4FZW-C nrPDB 102 2e-22 5ZRV-A nrPDB 102 2e-22 4JCS-A nrPDB 101 5e-22 6IUM-B nrPDB 100 7e-22 4JFC-A nrPDB 100 1e-21 4J2U-A nrPDB 99 3e-21 3HE2-A nrPDB 97 6e-21 3ZWA-A nrPDB 97 8e-21 3BPT-A nrPDB 94 8e-20 3T8B-A nrPDB 92 4e-19 3OME-A nrPDB 91 4e-19 2D3T-A nrPDB 90 1e-18 3HIN-A nrPDB 90 1e-18 2WTB-A nrPDB 89 3e-18 4ZU2-A nrPDB 86 3e-17 3I47-A nrPDB 84 7e-17 4HDT-A nrPDB 83 2e-16 4IZC-A nrPDB 81 4e-16 3LAO-A nrPDB 80 9e-16 5MRE-88 nrPDB 75 3e-14 2NP9-A nrPDB 75 4e-14 4Q1J-A nrPDB 74 9e-14 2A81-A nrPDB 73 1e-13 4JSB-A nrPDB 70 9e-13 3JU1-A nrPDB 68 4e-12 1XX4-A nrPDB 64 6e-11 4B3J-A nrPDB 64 7e-11 3HP0-A nrPDB 63 1e-10 3M6N-A nrPDB 59 3e-09 4HC8-A nrPDB 49 2e-06 4ZDC-A nrPDB 49 3e-06 5A1W-H nrPDB 28 3.3 1SJP-A nrPDB 27 7.5 5I1F-A nrPDB 27 9.5 >2DUB-A nrPDB Length = 261 Score = 536 bits (1381), Expect = e-153, Method: Compositional matrix adjust. Identities = 261/261 (100%), Positives = 261/261 (100%) Query: 30 GANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG 89 GANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG Sbjct: 1 GANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG 60 Query: 90 GEKAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMC 149 GEKAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMC Sbjct: 61 GEKAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMC 120 Query: 150 DIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLV 209 DIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLV Sbjct: 121 DIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLV 180 Query: 210 SKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFAT 269 SKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFAT Sbjct: 181 SKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFAT 240 Query: 270 DDRREGMSAFVEKRKANFKDH 290 DDRREGMSAFVEKRKANFKDH Sbjct: 241 DDRREGMSAFVEKRKANFKDH 261 >2HW5-A nrPDB Length = 286 Score = 498 bits (1281), Expect = e-141, Method: Compositional matrix adjust. Identities = 237/267 (88%), Positives = 256/267 (95%) Query: 24 FRRFASGANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVG 83 F+ ASGANF+YII EK+GKN++VGLIQLNRPKALNALC+GLI+ELNQAL+ FEEDPAVG Sbjct: 20 FQSMASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKIFEEDPAVG 79 Query: 84 AIVLTGGEKAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGC 143 AIVLTGG+KAFAAGADIKEMQN +FQDCYS KFL HWDH+T++KKPVIAAVNGYA GGGC Sbjct: 80 AIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGC 139 Query: 144 ELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDA 203 ELAMMCDIIYAGEKAQF QPEIL+GTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDA Sbjct: 140 ELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDA 199 Query: 204 KQAGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLF 263 KQAGLVSKI PVETLVEEAIQCAEKIA+NSKI+VAMAKESVNAAFEMTLTEG+KLEKKLF Sbjct: 200 KQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLF 259 Query: 264 YSTFATDDRREGMSAFVEKRKANFKDH 290 YSTFATDDR+EGM+AFVEKRKANFKD Sbjct: 260 YSTFATDDRKEGMTAFVEKRKANFKDQ 286 >3H81-A nrPDB Length = 278 Score = 276 bits (705), Expect = 9e-75, Method: Compositional matrix adjust. Identities = 129/256 (50%), Positives = 183/256 (71%), Gaps = 3/256 (1%) Query: 32 NFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGE 91 ++ I+ E+ + VG+I LNRP+ALNAL + ++ E+ A ++DP +GAI++TG Sbjct: 23 TYETILVER---DQRVGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITGSA 79 Query: 92 KAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDI 151 KAFAAGADIKEM + TF D ++ F + W + ++ P IAAV GYALGGGCELAMMCD+ Sbjct: 80 KAFAAGADIKEMADLTFADAFTADFFATWGKLAAVRTPTIAAVAGYALGGGCELAMMCDV 139 Query: 152 IYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSK 211 + A + A+FGQPEI LG +PG GG+QRLTRA+GK+ AM+++LTG + A +A+++GLVS+ Sbjct: 140 LIAADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSR 199 Query: 212 IFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDD 271 + P + L+ EA A I+ S MAKE+VN AFE +L+EG E++LF+S FAT+D Sbjct: 200 VVPADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATED 259 Query: 272 RREGMSAFVEKRKANF 287 + EGM+AF+EKR F Sbjct: 260 QSEGMAAFIEKRAPQF 275 >3MOY-A nrPDB Length = 263 Score = 261 bits (666), Expect = 4e-70, Method: Compositional matrix adjust. Identities = 128/261 (49%), Positives = 175/261 (67%) Query: 30 GANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG 89 G+ Y + VGLI+L+RP ALNAL L E+ A F+ D +GAIV+TG Sbjct: 3 GSMTTYTTIATSRPVAGVGLIRLDRPDALNALNQTLEAEVLDAARDFDADLEIGAIVVTG 62 Query: 90 GEKAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMC 149 E+AFAAGADI EM T LS WD +T+++KP++AAV GYALGGGCELAM+C Sbjct: 63 SERAFAAGADIAEMVTLTPHQARERNLLSGWDSLTQVRKPIVAAVAGYALGGGCELAMLC 122 Query: 150 DIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLV 209 D++ A + A+FGQPEI LG +PG GGTQRLTRAVGK+ AM++ LTG ++A++A++ GLV Sbjct: 123 DLVIAADTARFGQPEITLGILPGLGGTQRLTRAVGKAKAMDLCLTGRSLTAEEAERVGLV 182 Query: 210 SKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFAT 269 S+I P L++EA+ A++IA S+ K+++N AFE L+ G + E+ FY+ F T Sbjct: 183 SRIVPAADLLDEALAVAQRIARMSRPAGRAVKDAINEAFERPLSAGMRYERDAFYAMFDT 242 Query: 270 DDRREGMSAFVEKRKANFKDH 290 D+ EGM+AF+EKR F D Sbjct: 243 HDQTEGMTAFLEKRTPEFTDR 263 >4FZW-A nrPDB Length = 258 Score = 235 bits (599), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 118/246 (47%), Positives = 163/246 (66%) Query: 43 KNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKE 102 + V L+ LNRP A NAL N L+ +L LE D ++ V+TG + FAAGAD+ E Sbjct: 11 RQQRVLLLTLNRPAARNALNNALLMQLVNELEAAATDTSISVCVITGNARFFAAGADLNE 70 Query: 103 MQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQ 162 M + + W + KP+IAAVNGYALG GCELA++CD++ AGE A+FG Sbjct: 71 MAEKDLAATLNDTRPQLWARLQAFNKPLIAAVNGYALGAGCELALLCDVVVAGENARFGL 130 Query: 163 PEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEA 222 PEI LG +PGAGGTQRL R+VGKSLA +MVL+G+ I+AQ A+QAGLVS +FP + +E A Sbjct: 131 PEITLGIMPGAGGTQRLIRSVGKSLASKMVLSGESITAQQAQQAGLVSDVFPSDLTLEYA 190 Query: 223 IQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGMSAFVEK 282 +Q A K+A +S + + AK+++ + E+ L G E++LF AT+DR EG+SAF++K Sbjct: 191 LQLASKMARHSPLALQAAKQALRQSQEVALQAGLAQERQLFTLLAATEDRHEGISAFLQK 250 Query: 283 RKANFK 288 R +FK Sbjct: 251 RTPDFK 256 >5ZAI-A nrPDB Length = 259 Score = 223 bits (569), Expect = 5e-59, Method: Compositional matrix adjust. Identities = 123/258 (47%), Positives = 166/258 (64%), Gaps = 5/258 (1%) Query: 33 FQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEK 92 F+ I T+K+G ++ I LNRP LNAL L+EEL++A+ E DP + I++TG K Sbjct: 3 FETIETKKEG---NLFWITLNRPDKLNALNAKLLEELDRAVSQAESDPEIRVIIITGKGK 59 Query: 93 AFAAGADIKEMQNRTFQDCY--SGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCD 150 AF AGADI + T + + S K D I + KP IA +NGYALGGG ELA+ CD Sbjct: 60 AFCAGADITQFNQLTPAEAWKFSKKGREIMDKIEALSKPTIAMINGYALGGGLELALACD 119 Query: 151 IIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVS 210 I A E+AQ G PEI LG PG GGTQRLTR +GK A+EM++TGDRI +DA++ GLV+ Sbjct: 120 IRIAAEEAQLGLPEINLGIYPGYGGTQRLTRVIGKGRALEMMMTGDRIPGKDAEKYGLVN 179 Query: 211 KIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATD 270 ++ P+ L +E + AEKIA S I +A+ KE VN + L G LE + F+T+ Sbjct: 180 RVVPLANLEQETRKLAEKIAKKSPISLALIKEVVNRGLDSPLLSGLALESVGWGVVFSTE 239 Query: 271 DRREGMSAFVEKRKANFK 288 D++EG+SAF+EKR+ FK Sbjct: 240 DKKEGVSAFLEKREPTFK 257 >5Z7R-A nrPDB Length = 267 Score = 198 bits (503), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 106/252 (42%), Positives = 160/252 (63%), Gaps = 6/252 (2%) Query: 36 IITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG-GEKAF 94 +I EK+GK V ++ +NRPKALNAL + ++E++ + E D V A++LTG GEK+F Sbjct: 6 VILEKEGK---VAVVTINRPKALNALNSDTLKEMDYVIGEIENDSEVLAVILTGAGEKSF 62 Query: 95 AAGADIKEMQNRTFQDCYSGKFLSH--WDHITRIKKPVIAAVNGYALGGGCELAMMCDII 152 AGADI EM+ + L + + + ++KPVIAAVNG+ALGGGCE+AM CDI Sbjct: 63 VAGADISEMKEMNTIEGRKFGILGNKVFRRLELLEKPVIAAVNGFALGGGCEIAMSCDIR 122 Query: 153 YAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKI 212 A A+FGQPE+ LG PG GGTQRL+R VG +A +++ T I A +A + GLV+K+ Sbjct: 123 IASSNARFGQPEVGLGITPGFGGTQRLSRLVGMGMAKQLIFTAQNIKADEALRIGLVNKV 182 Query: 213 FPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDR 272 L+ A + A KI +N+ + V ++K+++N + + E + F F+T+D+ Sbjct: 183 VEPSELMNTAKEIANKIVSNAPVAVKLSKQAINRGMQCDIDTALAFESEAFGECFSTEDQ 242 Query: 273 REGMSAFVEKRK 284 ++ M+AF+EKRK Sbjct: 243 KDAMTAFIEKRK 254 >5JBW-A nrPDB Length = 260 Score = 146 bits (368), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 91/237 (38%), Positives = 129/237 (54%), Gaps = 11/237 (4%) Query: 59 NALCNGLIEELNQALETFEEDPAVGAIVLTG-GEKAFAAGADIKEMQN------RTFQDC 111 NA+ +++EL + + V A+V+TG G+KAF AGAD+KE R F D Sbjct: 26 NAISRAMLKELGELVTRVSSSRDVRAVVITGAGDKAFCAGADLKERATMAEDEVRAFLDG 85 Query: 112 YSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPEILLGTIP 171 F + I + IAA+NG ALGGG ELA+ CD+ A A+ G E+ LG IP Sbjct: 86 LRRTFRA----IEKSDCVFIAAINGAALGGGTELALACDLRVAAPAAELGLTEVKLGIIP 141 Query: 172 GAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAIQCAEKIAN 231 G GGTQRL R VG A +++LT RI+A +A GL +++ P L+ A AE + Sbjct: 142 GGGGTQRLARLVGPGRAKDLILTARRINAAEAFSVGLANRLAPEGHLLAVAYGLAESVVE 201 Query: 232 NSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGMSAFVEKRKANFK 288 N+ I VA AK +++ + L + LE + + T+DR EG+ AF EKR +K Sbjct: 202 NAPIAVATAKHAIDEGTGLELDDALALELRKYEEILKTEDRLEGLRAFAEKRAPVYK 258 >2PPY-A nrPDB Length = 265 Score = 137 bits (345), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 87/252 (34%), Positives = 142/252 (56%), Gaps = 9/252 (3%) Query: 43 KNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGA-IVLTGGEKAFAAGADIK 101 K + I L+ K+ N+ +E N A++ DP + IV++ K F+AGADI Sbjct: 15 KEDGIAEIHLHINKS-NSYDLEFYKEFNAAIDDIRFDPDIKVVIVMSDVPKFFSAGADIN 73 Query: 102 EMQNRTFQDCYSGKFL----SHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEK 157 + R+ + +F D I R + IA + G+ +GGG E+A+ CD+ + G++ Sbjct: 74 FL--RSADPRFKTQFCLFCNETLDKIARSPQVYIACLEGHTVGGGLEMALACDLRFMGDE 131 Query: 158 A-QFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVE 216 A + G PE+ LG + G GGTQRL R +G S A++M +TG+ I+ Q+A + GLV+++FP Sbjct: 132 AGKIGLPEVSLGVLAGTGGTQRLARLIGYSRALDMNITGETITPQEALEIGLVNRVFPQA 191 Query: 217 TLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGM 276 E + A K+AN++ V+ K ++ EM L + E +L F ++D +EG+ Sbjct: 192 ETRERTREYARKLANSATYAVSNIKLAIMNGKEMPLNVAIRYEGELQNLLFRSEDAKEGL 251 Query: 277 SAFVEKRKANFK 288 SAF+EKR+ N+K Sbjct: 252 SAFLEKRQPNWK 263 >5WYB-B nrPDB Length = 280 Score = 121 bits (303), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 83/250 (33%), Positives = 127/250 (50%), Gaps = 4/250 (1%) Query: 43 KNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG-GEKAFAAGADIK 101 K+ LI +N P A + LI L Q +E D + A+V+TG G K F+AGAD+ Sbjct: 23 KHGHTALITINHPPANTWDRDSLIG-LRQLIEHLNRDDDIYALVVTGQGPKFFSAGADLN 81 Query: 102 EMQN--RTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQ 159 + + + +F ++ + + IAA+NGYA+GGG E A+ CDI A +AQ Sbjct: 82 MFADGDKARAREMARRFGEAFEALRDFRGVSIAAINGYAMGGGLECALACDIRIAERQAQ 141 Query: 160 FGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLV 219 PE +G +P AGGTQ L VG+ A M+L +R+ A+ A + GLV ++ Sbjct: 142 MALPEAAVGLLPCAGGTQALPWLVGEGWAKRMILCNERVDAETALRIGLVEQVVDSGEAR 201 Query: 220 EEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGMSAF 279 A+ A K+A S + + K + A E E++ F F D REG++AF Sbjct: 202 GAALLLAAKVARQSPVAIRTIKPLIQGARERAPNTWLPEERERFVDLFDAQDTREGVNAF 261 Query: 280 VEKRKANFKD 289 +EKR +++ Sbjct: 262 LEKRDPKWRN 271 >4JWV-A nrPDB Length = 278 Score = 120 bits (302), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 90/263 (34%), Positives = 136/263 (51%), Gaps = 15/263 (5%) Query: 27 FASGANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIV 86 F S A+ + I V ++LNRP+ LNA+ + + L A + + A+V Sbjct: 20 FQSMADIDFRI------EGHVAHVRLNRPQGLNAITQEMDDLLLDAWTEVNANSDIWAVV 73 Query: 87 LTG-GEKAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCEL 145 L+ GEKAF GAD+ R + G + KKP++AAV G+ +GGG EL Sbjct: 74 LSAEGEKAFCIGADVSGGAERKTRMALGGGLTGIGGPLVTCKKPMVAAVQGFCVGGGFEL 133 Query: 146 AMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQ 205 AM DII A + AQFG PE +G I G R R + +A++++LTG+RI A +A+ Sbjct: 134 AMCADIIVAADTAQFGLPETKVGIIGECGVVHRAMRQLPYHIALQLILTGERIKADEARH 193 Query: 206 AGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKES----VNAAFEMTLTEGNKLEKK 261 GLV+++ P L E A++ A K+ S + V AK + + E+ L + E Sbjct: 194 YGLVNEVVPFAELEEAALRWASKLNAASPLAVQAAKAAALGRLGHPLEVALM--TRFEPI 251 Query: 262 LFYSTFATDDRREGMSAFVEKRK 284 Y+ AT+D++EG A E+RK Sbjct: 252 EEYA--ATEDKKEGERAAGERRK 272 >2IEX-A nrPDB Length = 272 Score = 120 bits (302), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 90/269 (33%), Positives = 132/269 (49%), Gaps = 26/269 (9%) Query: 32 NFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG-G 90 +++ II E + + I +NRP+ NA + E+ A +D +G I+LTG G Sbjct: 10 DYEDIIYETY---NGIAKITINRPEVHNAFRPKTVNEMIDAFTKARDDSNIGVIILTGAG 66 Query: 91 EKAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITR------------IKKPVIAAVNGYA 138 KAF +G D Q Y G+ D I R I KPVIA V GYA Sbjct: 67 GKAFCSGGD----QKVRGHGGYVGE-----DEIPRLNVLDLQRLIRVIPKPVIAMVAGYA 117 Query: 139 LGGGCELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRI 198 +GGG L ++CD+ A + A FGQ +G+ G G L R VG A E+ + Sbjct: 118 IGGGHVLHVVCDLTIAADNAIFGQTGPKVGSFDGGYGAGYLARIVGHKKAREIWYLCRQY 177 Query: 199 SAQDAKQAGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKL 258 +AQ+A + GLV+K+ P+E L EE ++ A++I S + K + NA + L +L Sbjct: 178 TAQEALEMGLVNKVVPLEQLEEETVKWAQEILEKSPTAIRFLKAAFNADSD-GLAGIQQL 236 Query: 259 EKKLFYSTFATDDRREGMSAFVEKRKANF 287 + T++ +EGM AF EKRK +F Sbjct: 237 AGDATLLFYTTEEAKEGMRAFKEKRKPDF 265 >5VE2-A nrPDB Length = 275 Score = 120 bits (302), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 73/244 (29%), Positives = 130/244 (53%), Gaps = 1/244 (0%) Query: 44 NSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEM 103 N+ V + +NRP+ NAL L L LE D + A++LT F AG D+ + Sbjct: 32 NNRVLSLTINRPELKNALNRELYAALADELERSNHDDQIRAVLLTANGDTFTAGNDLDDF 91 Query: 104 QNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQP 163 N ++ + + I+ + P++ AVNG A+G G + + CD++YA + A+F P Sbjct: 92 IN-PVEESGTPSVIRFLKAISECETPIVVAVNGPAIGVGLTMLLHCDMVYASKSARFRAP 150 Query: 164 EILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAI 223 +G +P A + L AVG++ A +++L G + A++A AGLV+++F + LV E++ Sbjct: 151 FTHVGLVPEAASSLLLPLAVGQAWANDLMLAGRILDAREALSAGLVTRVFEDDVLVAESL 210 Query: 224 QCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGMSAFVEKR 283 + AE++A+ + V +K + + + K E +F A+ + +E ++AF EKR Sbjct: 211 KIAEQVASLAPNSVKQSKRLIRGVNKEEVQAQMKREGVIFAEQLASAEFKESVAAFFEKR 270 Query: 284 KANF 287 +F Sbjct: 271 APHF 274 >1EF9-A nrPDB Length = 261 Score = 117 bits (294), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 79/264 (29%), Positives = 126/264 (47%), Gaps = 9/264 (3%) Query: 32 NFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVL--TG 89 ++QY+ K V +I+ N + LNAL I++L QAL P + I+L Sbjct: 2 SYQYVNVVTINK---VAVIEFNYGRKLNALSKVFIDDLMQALSDLNR-PEIRCIILRAPS 57 Query: 90 GEKAFAAGADIKEMQNRTFQD-CYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMM 148 G K F+AG DI E+ + Y I + KP+I+ V G GG E+ M Sbjct: 58 GSKVFSAGHDIHELPSGGRDPLSYDDPLRQITRMIQKFPKPIISMVEGSVWGGAFEMIMS 117 Query: 149 CDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGL 208 D+I A + F + LG G LTR G + E++ T I+AQ A G+ Sbjct: 118 SDLIIAASTSTFSMTPVNLGVPYNLVGIHNLTRDAGFHIVKELIFTASPITAQRALAVGI 177 Query: 209 VSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEK--KLFYST 266 ++ + VE L + +Q A I+ + + +A+ KE + E ++ E+ + + Sbjct: 178 LNHVVEVEELEDFTLQMAHHISEKAPLAIAVIKEELRVLGEAHTMNSDEFERIQGMRRAV 237 Query: 267 FATDDRREGMSAFVEKRKANFKDH 290 + ++D +EGM+AF+EKRK NF H Sbjct: 238 YDSEDYQEGMNAFLEKRKPNFVGH 261 >5KJP-A nrPDB Length = 265 Score = 116 bits (291), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 82/239 (34%), Positives = 124/239 (51%), Gaps = 3/239 (1%) Query: 49 LIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQNRTF 108 +I +NRPKA NA+ + L A++ + D + +LTGG +F AG D+K R Sbjct: 27 IITINRPKAKNAVNAAVSRGLADAMDQLDGDAGLSVAILTGGGGSFCAGMDLKAFA-RGE 85 Query: 109 QDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPEILLG 168 G+ L + KP+IAAV GYAL GG ELA+ D+I A + FG PE+ G Sbjct: 86 NVVVEGRGLGFTERPP--TKPLIAAVEGYALAGGTELALAADLIVAARDSAFGIPEVKRG 143 Query: 169 TIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAIQCAEK 228 + G GG RL + ++AME+ LTGD + A+ A + GLV+ + T ++ AI AEK Sbjct: 144 LVAGGGGLLRLPERIPYAIAMELALTGDNLPAERAHELGLVNVLAEPGTALDAAIALAEK 203 Query: 229 IANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGMSAFVEKRKANF 287 I N + V K + + + + K+ F ++D +EG AF E+R+ + Sbjct: 204 ITANGPLAVVATKRIITESRGWSPDTMFAEQMKILVPVFTSNDAKEGAIAFAERRRPRW 262 >2VSU-C nrPDB Length = 275 Score = 116 bits (290), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 76/250 (30%), Positives = 120/250 (48%), Gaps = 17/250 (6%) Query: 47 VGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQNR 106 + + LNRP+ NA+ L E+ LET E+DPA G +VLTG +A+ AG D+KE Sbjct: 19 IAFVILNRPEKRNAMSPTLNREMIDVLETLEQDPAAGVLVLTGAGEAWTAGMDLKEY--- 75 Query: 107 TFQDCYSGKFL-----------SHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAG 155 F++ +G + W + KP IA VNG+ GGG + CD+ Sbjct: 76 -FREVDAGPEILQEKIRREASQWQWKLLRMYAKPTIAMVNGWCFGGGFAPLVACDLAICA 134 Query: 156 EKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPV 215 ++A FG EI G PG ++ + VG ++ ++TG Q A + GLV++ P+ Sbjct: 135 DEATFGLSEINWGIPPGNLVSKAMADTVGHRQSLYYIMTGKTFGGQKAAEMGLVNESVPL 194 Query: 216 ETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEG-NKLEKKLFYSTFA-TDDRR 273 L E I+ A + + +++ AK E+T + + L KL S T R Sbjct: 195 AQLREVTIELARNLLEKNPVVLRAAKHGFKRCRELTWEQNEDYLYAKLDQSRLLDTGGRE 254 Query: 274 EGMSAFVEKR 283 +GM F++ + Sbjct: 255 QGMKQFLDDK 264 >3T88-A nrPDB Length = 289 Score = 115 bits (288), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 90/280 (32%), Positives = 142/280 (50%), Gaps = 17/280 (6%) Query: 15 LLSPVRCPEFRRFASGANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALE 74 L +PV E+ + G F+ I EK + I +NRP+ NA ++E+ QAL Sbjct: 13 LYAPV---EWHDCSEG--FEDIRYEKS--TDGIAKITINRPQVRNAFRPLTVKEMIQALA 65 Query: 75 TFEEDPAVGAIVLTG-GEKAFAAGADIKEMQNRT-FQDCYSGKFLSHWDHITRIK---KP 129 D +G I+LTG G+KAF +G D K + ++D L+ D +I+ KP Sbjct: 66 DARYDDNIGVIILTGAGDKAFCSGGDQKVRGDYGGYKDDSGVHHLNVLDFQRQIRTCPKP 125 Query: 130 VIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAM 189 V+A V GY++GGG L MMCD+ A + A FGQ +G+ G G + R VG+ A Sbjct: 126 VVAMVAGYSIGGGHVLHMMCDLTIAADNAIFGQTGPKVGSFDGGWGASYMARIVGQKKAR 185 Query: 190 EMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFE 249 E+ + A+ A GLV+ + P+ L +E ++ ++ NS + + K ++NA + Sbjct: 186 EIWFLCRQYDAKQALDMGLVNTVVPLADLEKETVRWCREMLQNSPMALRCLKAALNADCD 245 Query: 250 --MTLTEGNKLEKKLFYSTFATDDRREGMSAFVEKRKANF 287 L E LFY T++ +EG +AF +KR+ +F Sbjct: 246 GQAGLQELAGNATMLFY---MTEEGQEGRNAFNQKRQPDF 282 >4EML-A nrPDB Length = 275 Score = 111 bits (278), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 85/261 (32%), Positives = 128/261 (49%), Gaps = 18/261 (6%) Query: 43 KNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG------GEKAFAA 96 K + I +NRP NA + EL A ED +G ++LTG G+ AF + Sbjct: 16 KAGGIAKIVINRPHKRNAFRPQTVFELYDAFCNAREDNRIGVVLLTGAGPHSDGKYAFCS 75 Query: 97 GADIKEMQNRTFQDCYSGKFLSHWDH---ITRIKKPVIAAVNGYALGGGCELAMMCDIIY 153 G D + D L+ D I + K VIA V GYA+GGG L ++CD+ Sbjct: 76 GGDQSVRGEGGYIDDQGTPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGHVLHLVCDLTI 135 Query: 154 AGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIF 213 A + A FGQ +G+ G G+ L R VG+ A E+ + SAQ+A++ G+V+ + Sbjct: 136 AADNAIFGQTGPKVGSFDGGFGSSYLARIVGQKKAREIWYLCRQYSAQEAERMGMVNTVV 195 Query: 214 PVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFE----MTLTEGNKLEKKLFYSTFAT 269 PV+ L EE IQ A++I + S + + K + NA + + GN L Y + T Sbjct: 196 PVDRLEEEGIQWAKEILSKSPLAIRCLKAAFNADCDGQAGLQELAGN---ATLLY--YMT 250 Query: 270 DDRREGMSAFVEKRKANFKDH 290 ++ EG AF+EKR +F + Sbjct: 251 EEGSEGKQAFLEKRPPDFSQY 271 >6OJM-A nrPDB Length = 286 Score = 111 bits (277), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 84/265 (31%), Positives = 131/265 (49%), Gaps = 30/265 (11%) Query: 43 KNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG-------GEKAFA 95 K + V I NRP+ NA EL A EDP++G ++L+G G AF Sbjct: 25 KCNGVARIAFNRPEIRNAFRPKTTSELYDAFYDAYEDPSIGVVLLSGEGPSPKDGGWAFC 84 Query: 96 AGADIKEMQNRTFQDCYSGKFLSHWDHITRIK-------KPVIAAVNGYALGGGCELAMM 148 +G D K ++ Y G+ H +I ++ K VIA V G+A+GGG L ++ Sbjct: 85 SGGDQKARGHQG----YVGEDGRHRLNILEVQRLIRFMPKVVIAVVPGWAVGGGHSLHVV 140 Query: 149 CDIIYAG-EKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAG 207 CD+ A E A F Q + + + G G+ L + VG+ A E+ G SAQ+A + G Sbjct: 141 CDLTLASKEHAIFKQTDADVTSFDGGYGSAYLAKMVGQKKAREIFFLGRNYSAQEAFEMG 200 Query: 208 LVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYS-- 265 +V+K+ P L + A + A++I S + M K F M LT+ + +++F Sbjct: 201 MVNKVVPHAELEDTAYEWAQEILAKSPTSIRMLK------FAMNLTDDGMVGQQVFAGEA 254 Query: 266 ---TFATDDRREGMSAFVEKRKANF 287 + TD+ +EG +AF+EKRK +F Sbjct: 255 TRLAYMTDEAKEGRNAFLEKRKPDF 279 >2UZF-A nrPDB Length = 273 Score = 110 bits (276), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 82/252 (32%), Positives = 123/252 (48%), Gaps = 25/252 (9%) Query: 50 IQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG-GEKAFAAGADIKEMQNRTF 108 + +NRP+ NA + E+ A +D V IVLTG G+ AF +G D Q + Sbjct: 26 VTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEGDLAFCSGGD----QKKRG 81 Query: 109 QDCYSGKFLSHWDHITR------------IKKPVIAAVNGYALGGGCELAMMCDIIYAGE 156 Y G+ D I R I KPVIA V GYA+GGG L ++CD+ A + Sbjct: 82 HGGYVGE-----DQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNVVCDLTIAAD 136 Query: 157 KAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVE 216 A FGQ +G+ G+ L R VG A E+ + +AQ+A GLV+ + P+E Sbjct: 137 NAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMGLVNTVVPLE 196 Query: 217 TLVEEAIQCAEKIANNSKIIVAMAKESVNAAFE-MTLTEGNKLEKKLFYSTFATDDRREG 275 + +E +Q ++I +S + K ++NA + + + + L Y T TD+ +EG Sbjct: 197 KVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYT--TDEAKEG 254 Query: 276 MSAFVEKRKANF 287 AF EKR +F Sbjct: 255 RDAFKEKRDPDF 266 >1NZY-B nrPDB Length = 269 Score = 107 bits (268), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 72/249 (28%), Positives = 126/249 (50%), Gaps = 11/249 (4%) Query: 47 VGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQNR 106 V I + P+ NAL ++E+ AL EED +VGA+++TG E AF AG ++E+ Sbjct: 13 VAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREIPLD 72 Query: 107 T----FQDCYSGKFLSHWDH-----ITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEK 157 +D + + + W H I R+K+PV+AA+NG A GGG +++ D+ + Sbjct: 73 KGVAGVRDHF--RIAALWWHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICADS 130 Query: 158 AQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVET 217 A+F +G + L R VG AME++LT + ++AK GLVS+++P + Sbjct: 131 AKFVCAWHTIGIGNDTATSYSLARIVGMRRAMELMLTDRTLYPEEAKDWGLVSRVYPKDE 190 Query: 218 LVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGMS 277 E A + A ++A + MAKE +A + + E + E + ++ ++ Sbjct: 191 FREVAWKVARELAAAPTHLQVMAKERFHAGWMQPVEECTEFEIQNVIASVTHPHFMPCLT 250 Query: 278 AFVEKRKAN 286 F++ +A+ Sbjct: 251 RFLDGHRAD 259 >5YLO-A nrPDB Length = 271 Score = 107 bits (268), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 77/250 (30%), Positives = 117/250 (46%), Gaps = 5/250 (2%) Query: 44 NSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEM 103 + + + LNRP+ NAL +E L+ L+ E DPAV A+VL G ++F AGAD+ E Sbjct: 12 EAGIAWLVLNRPQQRNALDIPTLEALHVRLDACERDPAVRAVVLGGSGRSFCAGADLAEW 71 Query: 104 ---QNRTFQDCYSGKFLSH--WDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKA 158 + R + Y +H + + KP +AAVNG A+G G +LA+ CD A A Sbjct: 72 AAAEARGELESYGWTEAAHALMGRLHALDKPTVAAVNGSAVGAGMDLALCCDFRIAAASA 131 Query: 159 QFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETL 218 +F + P AG + L R +G A ++ + SA+ A AGLV ++ E L Sbjct: 132 RFKAGYTGMAYCPDAGASWHLPRLLGSEAAKRLLFLDEAWSAERALGAGLVGEVVADEHL 191 Query: 219 VEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGMSA 278 VE A ++A+ A K + +L E + E+ ++D E + A Sbjct: 192 VEAVGAFAARLASGPTFAFAQTKRLLRDGAGRSLAEQLRAEQAAGLLCGRSEDAAEALRA 251 Query: 279 FVEKRKANFK 288 EKR F Sbjct: 252 VAEKRSPQFS 261 >4FZW-C nrPDB Length = 274 Score = 102 bits (255), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 80/247 (32%), Positives = 127/247 (51%), Gaps = 6/247 (2%) Query: 47 VGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQ-N 105 V + LNRP+ LN+ + + +L + L+ E D + ++LTG + F AG D+ + + Sbjct: 25 VMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNVD 84 Query: 106 RTFQDCYSGKFLSHW-----DHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQF 160 T G + + + ++ KPVI AVNG A G G LA+ DI+ A A+F Sbjct: 85 PTGPAPDLGMSVERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKF 144 Query: 161 GQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVE 220 LG IP GGT L R G++ AM + L G+++SA+ A + G++ ++ ETL + Sbjct: 145 VMAFSKLGLIPDCGGTWLLPRVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLAD 204 Query: 221 EAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGMSAFV 280 A Q A +A + + K+++N+A TL LE+ + D REG+SAF+ Sbjct: 205 TAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAGRSADYREGVSAFL 264 Query: 281 EKRKANF 287 KR F Sbjct: 265 AKRSPQF 271 >5ZRV-A nrPDB Length = 763 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 64/178 (35%), Positives = 99/178 (55%), Gaps = 7/178 (3%) Query: 42 GKNSSVGLIQLNRPKA-LNALCNGLIEELNQAL-ETFEEDPAVGAIVLTGGEKAFAAGAD 99 G V ++++N P + +N L L E ++ + E + D A++++ F AGAD Sbjct: 44 GVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGAD 103 Query: 100 IKEMQN-RTFQDC--YSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCD--IIYA 154 I + +T Q+ S + + + + KP++AA+NG LGGG E+A+ C I Sbjct: 104 INMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATK 163 Query: 155 GEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKI 212 K G PE+LLG +PGAGGTQRL + VG A++M+LTG I A AK+ GLV ++ Sbjct: 164 DRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQL 221 >4JCS-A nrPDB Length = 286 Score = 101 bits (251), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 74/269 (27%), Positives = 127/269 (47%), Gaps = 21/269 (7%) Query: 33 FQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEK 92 FQ + T ++VG I++NR N L +L LE +D + +VLT Sbjct: 20 FQSMDTLDFEVVNNVGWIRMNRAAKHNPFDAELRADLMTVLERVRDDADIRVLVLTSHPG 79 Query: 93 AFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIK-------------KPVIAAVNGYAL 139 +F AG ++ +++ + SG ++W RIK +PVIAAV+G A Sbjct: 80 SFCAGGNLHVLRD----NLDSGP--AYWQQ--RIKTGLRFIHDMLNLGRPVIAAVDGPAF 131 Query: 140 GGGCELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRIS 199 G G L++ DI+ A +A+F + LG +P G L RAVG A E++ + + Sbjct: 132 GAGFALSLTADIVLASPRARFSMAYLRLGLVPDLGALYLLPRAVGLQRAKELMFSTRELD 191 Query: 200 AQDAKQAGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLE 259 A++A + GLV ++ E L + A + AE + + +A+ K ++N + + LE Sbjct: 192 AEEAHRLGLVMEVHESEALEQRAREIAESLVQAAPTALALTKAALNVSLDSDEQTMFSLE 251 Query: 260 KKLFYSTFATDDRREGMSAFVEKRKANFK 288 + F+T + R + A + K+ F+ Sbjct: 252 AASQAAAFSTKEPRAAIEALLSKQPPPFR 280 >6IUM-B nrPDB Length = 701 Score = 100 bits (249), Expect = 7e-22, Method: Compositional matrix adjust. Identities = 75/203 (36%), Positives = 109/203 (53%), Gaps = 36/203 (17%) Query: 44 NSSVGLIQLNRPKALNALCN----GLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGAD 99 V +I L+ P +N L + G++E + +AL+ D AV AIV+TG KAF+ GAD Sbjct: 8 QDGVAVITLDNP-PVNGLGHSTRLGIVEGMTRALD----DAAVKAIVITGAGKAFSGGAD 62 Query: 100 IKE------MQNRTFQDCYSGKFLSHWDHITRI----KKPVIAAVNGYALGGGCELAMMC 149 I+E MQ T + R+ KPV+AAV+ A+GGG ELA+ C Sbjct: 63 IREFNTPKAMQEPTLHS------------VIRVLEGSSKPVVAAVHSVAMGGGLELALGC 110 Query: 150 DIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLV 209 + A + AQ PE+ LG +PGAGGTQRL R +G A M+++G + ++ K AG Sbjct: 111 NYRVASKGAQIALPEVKLGLLPGAGGTQRLPRVIGLEAAANMIVSGTPVLSE--KFAG-- 166 Query: 210 SKIFPVETLVEEAIQCAEKIANN 232 +K+F E + + + A K A N Sbjct: 167 TKLFD-EIVDGDVLPAAVKFAQN 188 >4JFC-A nrPDB Length = 281 Score = 99.8 bits (247), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 78/245 (31%), Positives = 126/245 (51%), Gaps = 5/245 (2%) Query: 49 LIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQ-NRT 107 ++ L+ P+ NAL + +AL E +P + ++V+TG F AG +++ +Q NR Sbjct: 37 ILTLSNPEFRNALGPEIYAAGIEALNAAENNPEIRSVVITGEGAVFCAGGNLQRLQANRR 96 Query: 108 FQ---DCYSGKFLSHW-DHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQP 163 S + L +W D I KPVIAAV G A G G LA+ CD + A A F Sbjct: 97 EAPEVQAQSIEGLHNWIDSIRTYPKPVIAAVEGAAAGAGFSLALACDFVVAASNAVFVMS 156 Query: 164 EILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAI 223 +G P GG+ L R++ ++LA E+++ G+RISAQ GLV+K+ + EA+ Sbjct: 157 YSTVGLSPDGGGSWSLARSLPRALASELLMGGERISAQRLHDLGLVNKVASAGDALSEAL 216 Query: 224 QCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGMSAFVEKR 283 + A ++ + +A KE +N A TL++ E+ F + EG++AF+ KR Sbjct: 217 RMAGQLNARAPNALASIKELINEASSNTLSQQLACERDHFVRNLHHSNGGEGIAAFLGKR 276 Query: 284 KANFK 288 ++ Sbjct: 277 TPQYR 281 >4J2U-A nrPDB Length = 365 Score = 98.6 bits (244), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 61/180 (33%), Positives = 91/180 (50%), Gaps = 10/180 (5%) Query: 43 KNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG-GEKAFAAGADIK 101 K G I L+RP ALNAL +++E++ AL + DP V +V+ G +AF AG DI Sbjct: 30 KVRRAGRITLSRPAALNALTCAMVQEIDAALRGWIGDPEVELVVIDAEGPRAFCAGGDIA 89 Query: 102 EMQNRTF-------QDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYA 154 E+ R QD + ++ + D I KP+++ + G+ +GGG L Sbjct: 90 ELHGRGVAGDHAFGQDFWRVEYRMN-DRIAAFPKPIVSLMQGFTMGGGVGLGCHARHRIV 148 Query: 155 GEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFP 214 GE +Q PE +G +P GGT L RA G+ + + + LTG R+ DA AG + P Sbjct: 149 GETSQISMPECAIGLVPDVGGTHLLARAPGR-IGVWLGLTGARMGPGDAIFAGFADRFVP 207 >3HE2-A nrPDB Length = 264 Score = 97.4 bits (241), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 79/258 (30%), Positives = 122/258 (47%), Gaps = 18/258 (6%) Query: 39 EKKGKNSSVGL--------IQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGG 90 + +G S +G+ I+L RP+ NAL + L+EEL QA+ D + AIVLTG Sbjct: 15 QTQGPGSMIGITQAEAVLTIELQRPERRNALNSQLVEELTQAIRK-AGDGSARAIVLTGQ 73 Query: 91 EKAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCD 150 AF AGAD+ F Y + + + PV+ A+NG A+G G +LAM CD Sbjct: 74 GTAFCAGADLS---GDAFAADYPDRLIELHKAMDASPMPVVGAINGPAIGAGLQLAMQCD 130 Query: 151 IIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVS 210 + A F P G +RL+ VG A M+L+ ++++A+ A G+ + Sbjct: 131 LRVVAPDAFFQFPTSKYGLALDNWSIRRLSSLVGHGRARAMLLSAEKLTAEIALHTGMAN 190 Query: 211 KIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATD 270 +I TL + AE IA + + + AK +N + + E K+LF + + Sbjct: 191 RI---GTLADAQAWAAE-IARLAPLAIQHAKRVLND--DGAIEEAWPAHKELFDKAWGSQ 244 Query: 271 DRREGMSAFVEKRKANFK 288 D E A +EKR F+ Sbjct: 245 DVIEAQVARMEKRPPKFQ 262 >3ZWA-A nrPDB Length = 742 Score = 97.1 bits (240), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 75/187 (40%), Positives = 107/187 (57%), Gaps = 8/187 (4%) Query: 46 SVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQN 105 S+ +I+L P +NA+ +I E+ L+ D V AIV+ G F AGADI Sbjct: 30 SLAMIRLCNP-PVNAVSPTVIREVRNGLQKAGSDHTVKAIVICGANGNFCAGADI----- 83 Query: 106 RTFQDCYSGKFL-SHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPE 164 F G L S D I R +KPV+AA+ G ALGGG ELA+ C A KA+ G PE Sbjct: 84 HGFSAFTPGLALGSLVDEIQRYQKPVLAAIQGVALGGGLELALGCHYRIANAKARVGLPE 143 Query: 165 ILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAIQ 224 + LG +PGA GTQ L R VG +A++++ +G +SA +A + G++ + + VEEAI+ Sbjct: 144 VTLGILPGARGTQLLPRVVGVPVALDLITSGKYLSADEALRLGILDAVVKSDP-VEEAIK 202 Query: 225 CAEKIAN 231 A+KI + Sbjct: 203 FAQKIID 209 >3BPT-A nrPDB Length = 363 Score = 93.6 bits (231), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 62/183 (33%), Positives = 91/183 (49%), Gaps = 7/183 (3%) Query: 42 GKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG-GEKAFAAGADI 100 GK G+I LNRPK LNAL +I ++ L+ +E+DP I++ G G KAF AG DI Sbjct: 11 GKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDI 70 Query: 101 KEMQN--RTFQDCYSGKFLSHW---DHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAG 155 + + + Q F + + + +KP +A ++G +GGG L++ A Sbjct: 71 RVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVAT 130 Query: 156 EKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPV 215 EK F PE +G P GG L R GK L + LTG R+ +D +AG+ + Sbjct: 131 EKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRDVYRAGIATHFVDS 189 Query: 216 ETL 218 E L Sbjct: 190 EKL 192 >3T8B-A nrPDB Length = 334 Score = 91.7 bits (226), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 78/278 (28%), Positives = 123/278 (44%), Gaps = 34/278 (12%) Query: 37 ITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG------- 89 IT + + + + NRP+ NA ++EL + L+ P VG ++LTG Sbjct: 57 ITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKD 116 Query: 90 GEKAFAAGADIKEMQNRTFQDCYSGKFLSHWD-------HITRIK-------KPVIAAVN 135 G AF +G D + ++ R+ SG D HI ++ K VI VN Sbjct: 117 GGWAFCSGGD-QRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVN 175 Query: 136 GYALGGGCELAMMCDIIYAG-EKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLT 194 G+A GGG L ++CD+ A E A+F Q + +G+ G G+ L R VG+ A E+ Sbjct: 176 GWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFL 235 Query: 195 GDRISAQDAKQAGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTE 254 G +A+ Q G V+ + L +Q A +I S M K F L + Sbjct: 236 GRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLK------FAFNLLD 289 Query: 255 GNKLEKKLFYS-----TFATDDRREGMSAFVEKRKANF 287 + ++LF + TD+ EG AF++KR ++ Sbjct: 290 DGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDW 327 >3OME-A nrPDB Length = 282 Score = 91.3 bits (225), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 66/218 (30%), Positives = 109/218 (50%), Gaps = 13/218 (5%) Query: 42 GKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIK 101 G S+ I LNRP+A NA L++EL+ A ED V I+L K F+AG D++ Sbjct: 28 GVADSIATITLNRPEAANAQNPELLDELDAAWTRAAEDNEVKVIILRANGKHFSAGHDLR 87 Query: 102 ---EMQNRTFQDCY----SGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYA 154 E+ + + + ++L + + KP IAAV G + GG L CD+I A Sbjct: 88 GGGEVPEKISLEFIIQHEARRYLDYTLRWRNVPKPSIAAVQGRCISGGLLLCWPCDLILA 147 Query: 155 GEKAQFGQPEILLGTIPGAGGTQR--LTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKI 212 + A F P L+G GG + T +G A E++ TG ++A++A++ G+V+++ Sbjct: 148 SDDALFSDPVALMGI----GGVEYHGHTWELGPRKAKEILFTGRALTAEEAERTGMVNRV 203 Query: 213 FPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEM 250 + L + + AE+IA + AK +VN ++ Sbjct: 204 VARDELDAQTRELAEQIATMPPFALRQAKRAVNQTLDV 241 >2D3T-A nrPDB Length = 715 Score = 90.1 bits (222), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 55/182 (30%), Positives = 93/182 (51%), Gaps = 14/182 (7%) Query: 48 GLIQLN---RPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKE-M 103 G+++L + +++N + EL QA++ + D +V ++++ G+ F GADI E + Sbjct: 16 GIVELKFDLKGESVNKFNRLTLNELRQAVDAIKADASVKGVIVSSGKDVFIVGADITEFV 75 Query: 104 QNRTFQDCY-------SGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGE 156 +N D + K S ++ + P +AA+NG ALGGG E+ + D + Sbjct: 76 ENFKLPDAELIAGNLEANKIFSDFEDLNV---PTVAAINGIALGGGLEMCLAADFRVMAD 132 Query: 157 KAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVE 216 A+ G PE+ LG PG GGT RL R +G A+E + +G A+DA + V + + Sbjct: 133 SAKIGLPEVKLGIYPGFGGTVRLPRLIGVDNAVEWIASGKENRAEDALKVSAVDAVVTAD 192 Query: 217 TL 218 L Sbjct: 193 KL 194 >3HIN-A nrPDB Length = 275 Score = 89.7 bits (221), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 72/247 (29%), Positives = 116/247 (46%), Gaps = 14/247 (5%) Query: 50 IQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQNRTFQ 109 I LNRPK NAL +GL+ L L + + A+V+ G F+AG D+ E++ R Sbjct: 29 IGLNRPKKRNALNDGLMAALKDCLTDIPDQ--IRAVVIHGIGDHFSAGLDLSELRERDAT 86 Query: 110 D--CYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPEILL 167 + +S + +D I + PVIAA+ G +GGG ELA I A A + PE Sbjct: 87 EGLVHSQTWHRVFDKIQYCRVPVIAALKGAVIGGGLELACAAHIRVAEASAYYALPEGSR 146 Query: 168 GTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAIQCAE 227 G G GG+ RL R +G + +M+LTG SA + G + + ++A++ Sbjct: 147 GIFVGGGGSVRLPRLIGVARMADMMLTGRVYSAAEGVVHGFSQYLIENGSAYDKALELGN 206 Query: 228 KIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFAT-----DDRREGMSAFVEK 282 ++A N+ + +V A M + E N L S AT + + + AF++ Sbjct: 207 RVAQNAP----LTNFAVLQALPM-IAEANPQTGLLMESLMATVAQSDQEAKTRIRAFLDH 261 Query: 283 RKANFKD 289 + A ++ Sbjct: 262 KTAKVRE 268 >2WTB-A nrPDB Length = 725 Score = 88.6 bits (218), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 76/199 (38%), Positives = 106/199 (53%), Gaps = 10/199 (5%) Query: 47 VGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIK---EM 103 V +I L P +N+L ++ L E V AIV+TG + F+ G DI EM Sbjct: 18 VAVITLINP-PVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGEM 76 Query: 104 QNRTFQDCYSGKFLSHWDHITRI----KKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQ 159 Q ++ +G ++S D IT + +KP +AA++G ALGGG ELAM C + AQ Sbjct: 77 QKGNVKEPKAG-YIS-IDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQ 134 Query: 160 FGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLV 219 G PE+ LG IPG GGTQRL R VG + A+EM+LT + A++ GL+ + P LV Sbjct: 135 LGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELV 194 Query: 220 EEAIQCAEKIANNSKIIVA 238 A + A I K V+ Sbjct: 195 TTARRWALDIVGRRKPWVS 213 >4ZU2-A nrPDB Length = 272 Score = 85.5 bits (210), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 79/256 (30%), Positives = 116/256 (45%), Gaps = 37/256 (14%) Query: 50 IQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQN---- 105 I LNRP++ NA+ ++ EL L +D +V A+VL G + F AG DIK+M Sbjct: 20 ITLNRPQSRNAMSLAMVGELRAVLAAVRDDRSVRALVLRGADGHFCAGGDIKDMAGARAA 79 Query: 106 -----RTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQF 160 RT + G L ++ ++A V G LGGG LA + D+ A AQF Sbjct: 80 GAEAYRTLNRAF-GSLLEEAQAAPQL---LVALVEGAVLGGGFGLACVSDVAIAAADAQF 135 Query: 161 GQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLV----SKIFPVE 216 G PE LG +P A + R +G + A + LT R ++A + GLV + +E Sbjct: 136 GLPETSLGILP-AQIAPFVVRRIGLTQARRLALTAARFDGREALRLGLVHFCEADADALE 194 Query: 217 TLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTL--TEGNKLEKKL------FYSTFA 268 +EE ++ + A N+ NAA + L +E +L L F Sbjct: 195 QRLEETLEQLRRCAPNA-----------NAATKALLLASESGELGALLDDAARQFAEAVG 243 Query: 269 TDDRREGMSAFVEKRK 284 + EG AFV+KRK Sbjct: 244 GAEGSEGTLAFVQKRK 259 >3I47-A nrPDB Length = 268 Score = 84.0 bits (206), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 81/258 (31%), Positives = 126/258 (48%), Gaps = 25/258 (9%) Query: 47 VGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQN- 105 VGL+ +NR NA N L+ E+ L++ D V IVL K F+AGAD+ MQ+ Sbjct: 14 VGLLTMNRISKHNAFDNQLLTEMRIRLDSAINDTNVRVIVLKANGKHFSAGADLTWMQSM 73 Query: 106 ------RTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQ 159 +D L + I++ KP IA V G A GGG LA CDI A A+ Sbjct: 74 ANFTEEENLEDSLVLGNLMY--SISQSPKPTIAMVQGAAFGGGAGLAAACDIAIASTSAR 131 Query: 160 FGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLV 219 F E+ LG IP A + + RA+G+ A + ++ + A A LV P +TL+ Sbjct: 132 FCFSEVKLGLIP-AVISPYVVRAIGERAAKMLFMSAEVFDATRAYSLNLVQHCVPDDTLL 190 Query: 220 EEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGN-KLEKKLFYSTFA-------TDD 271 E ++ A +I+NN A E+V + ++ N K++++L T + +D+ Sbjct: 191 EFTLKYASQISNN-------APEAVKNSKQLAQYVANKKIDEELVRYTASLIAHKRVSDE 243 Query: 272 RREGMSAFVEKRKANFKD 289 +EG+ AF+ K N+ + Sbjct: 244 GQEGLKAFLNKEIPNWNE 261 >4HDT-A nrPDB Length = 353 Score = 82.8 bits (203), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 59/182 (32%), Positives = 92/182 (50%), Gaps = 11/182 (6%) Query: 47 VGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG-GEKAFAAGADIKEMQN 105 VGL+ LNRPKA+N+L +G++ + + L +E D +V A++LTG GE+ AG D+ + + Sbjct: 19 VGLLTLNRPKAINSLTHGMVTTMAERLAAWENDDSVRAVLLTGAGERGLCAGGDVVAIYH 78 Query: 106 RTFQDCYSGKFLSHW-------DHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKA 158 D + W HI R KP ++ ++G +GGG + ++ + Sbjct: 79 SAKADGAEARRF--WFDEYRLNAHIGRYPKPYVSIMDGIVMGGGVGVGAHGNVRVVTDTT 136 Query: 159 QFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETL 218 + PE+ +G IP GGT L+RA GK L + LTG S DA G P + + Sbjct: 137 KMAMPEVGIGFIPDVGGTYLLSRAPGK-LGLHAALTGAPFSGADAIVMGFADHYVPHDKI 195 Query: 219 VE 220 E Sbjct: 196 DE 197 >4IZC-A nrPDB Length = 275 Score = 81.3 bits (199), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 62/194 (31%), Positives = 93/194 (47%), Gaps = 6/194 (3%) Query: 43 KNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKE 102 +++ V ++ LNRP NAL IEEL T V A+VLTG F AG D+ E Sbjct: 17 RDNGVCVVTLNRPDKRNALDVATIEELVTFFSTAHR-KGVRAVVLTGAGDHFCAGLDLVE 75 Query: 103 MQ--NRTFQDCYSGKFLSH--WDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKA 158 +R+ D H ++ + P+IAA+ G +GGG LA + + Sbjct: 76 HWKADRSADDFMHVCLRWHEAFNKMEYGGVPIIAALRGAVVGGGLALASAAHLRVMDQST 135 Query: 159 QFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETL 218 F PE G G G T R++ +GK ++M+LTG Q+A GL I + Sbjct: 136 YFALPEGQRGIFTGGGATIRVSDMIGKYRMIDMILTGRVYQGQEAADLGLAQYITEGSSF 195 Query: 219 VEEAIQCAEKIANN 232 ++A++ A+KIA+N Sbjct: 196 -DKAMELADKIASN 208 >3LAO-A nrPDB Length = 258 Score = 80.5 bits (197), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 67/239 (28%), Positives = 109/239 (45%), Gaps = 11/239 (4%) Query: 49 LIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQNRTF 108 LI L+R NA + ++ +L A+ +E VL + F AG D+ E+ + Sbjct: 24 LIGLDRAGKRNAFDSAMLADLALAMGEYERSEESRCAVLFAHGEHFTAGLDLMELAPKLA 83 Query: 109 QDC--YSGKFLSHWDHI-TRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPEI 165 Y + W + R KP++ AV G G EL + DI A +F E+ Sbjct: 84 ASGFRYPDGGVDPWGVVQPRRSKPLVVAVQGTCWTAGIELMLNADIAVAARGTRFAHLEV 143 Query: 166 LLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAIQC 225 L G P G T R RA G + AM +LTGD A +A + L++++ + A++ Sbjct: 144 LRGIPPLGGSTVRFPRAAGWTDAMRYILTGDEFDADEALRMRLLTEVVEPGEELARALEY 203 Query: 226 AEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFA----TDDRREGMSAFV 280 AE+IA + + V + ++ +AF+ EG+ + A ++D REG+ A V Sbjct: 204 AERIARAAPLAV---RAALQSAFQ-GRDEGDDAALSRVNESLAALIGSEDVREGVLAMV 258 >5MRE-88 nrPDB Length = 457 Score = 75.1 bits (183), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 56/194 (28%), Positives = 87/194 (44%), Gaps = 25/194 (12%) Query: 49 LIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEK--AFAAGADI------ 100 +I LNRPK LNAL + E + + L + + ++L + +F AG D+ Sbjct: 14 VITLNRPKKLNALNAEMSESMFKTLNEYAKSDTTNLVILKSSNRPRSFCAGGDVATVAIF 73 Query: 101 ---KEMQN--RTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAG 155 KE + F D YS F I KP++ ++G +GGG L++ A Sbjct: 74 NFNKEFAKSIKFFTDEYSLNF-----QIATYLKPIVTFMDGITMGGGVGLSIHTPFRIAT 128 Query: 156 EKAQFGQPEILLGTIPGAGGTQRLTRAV-----GKSLAMEMVLTGDRISAQDAKQAGLVS 210 E ++ PE+ +G P G T L R V +A+ + LTG+ ++ DA GL S Sbjct: 129 ENTKWAMPEMDIGFFPDVGSTFALPRIVTLANSNSQMALYLCLTGEVVTGADAYMLGLAS 188 Query: 211 KIFPVETLVEEAIQ 224 E L +A+Q Sbjct: 189 HYVSSENL--DALQ 200 >2NP9-A nrPDB Length = 440 Score = 74.7 bits (182), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 65/251 (25%), Positives = 112/251 (44%), Gaps = 39/251 (15%) Query: 2 AALRALL--PRACNSLLSPVR-----CPEFRRFASGANFQYIITEKKGKNSSVGLIQLNR 54 A LR+ L P +++L P PEF R + + E++ V + + R Sbjct: 129 AVLRSPLAGPHLLDAMLRPTPRALELLPEFVRTGE-VEMEAVHLERR---DGVARLTMCR 184 Query: 55 PKALNALCNGLIEELNQALETFEEDPAVGAIVLTGG---------EKAFAAGADIKEMQ- 104 LNA ++++ A++ DP V +L GG ++ F+AG ++K + Sbjct: 185 DDRLNAEDGQQVDDMETAVDLALLDPGVRVGLLRGGVMSHPRYRGKRVFSAGINLKYLSQ 244 Query: 105 -----------------NRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAM 147 ++ + + W H RI+KP +AAV+G+A+GGG +L + Sbjct: 245 GGISLVDFLMRRELGYIHKLVRGVLTNDDRPGWWHSPRIEKPWVAAVDGFAIGGGAQLLL 304 Query: 148 MCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAG 207 + D + A A F P G IPGA RL R G ++ +++L G RI A++ + Sbjct: 305 VFDRVLASSDAYFSLPAAKEGIIPGAANL-RLGRFAGPRVSRQVILEGRRIWAKEPEARL 363 Query: 208 LVSKIFPVETL 218 LV ++ + L Sbjct: 364 LVDEVVEPDEL 374 >4Q1J-A nrPDB Length = 268 Score = 73.6 bits (179), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 49/188 (26%), Positives = 92/188 (48%), Gaps = 1/188 (0%) Query: 59 NALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQNRTFQDCYSGKFLS 118 NA L ++L QA E ++P A++LTG + FA+G +E R Q + Sbjct: 46 NAFSQELTDDLIQAFEYIRQNPKYKAVILTGYDNYFASGG-TQEGLLRIQQGLTKFTDDN 104 Query: 119 HWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQR 178 + + PVIAA+ G+ +GGG + + DI+ ++ + + G PG G T Sbjct: 105 LYSLALDCEIPVIAAMQGHGIGGGFVMGLFADIVILSRESVYTANFMKYGFTPGMGATFI 164 Query: 179 LTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAIQCAEKIANNSKIIVA 238 + + +G SLA E++L D ++ G+ K+ P +++ A++ A+++A + + Sbjct: 165 VPKKLGFSLAQEILLNAGSYRGADLEKRGVPFKVLPRAEVLDYAVELAQELAEKPRNSLV 224 Query: 239 MAKESVNA 246 K+ + A Sbjct: 225 TLKDHLVA 232 >2A81-A nrPDB Length = 250 Score = 73.2 bits (178), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 61/229 (26%), Positives = 100/229 (43%), Gaps = 5/229 (2%) Query: 47 VGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGG-EKAFAAGADIKEMQN 105 V +I L+ P N L + AL D +V A+V+ GG E++F+AG D E++ Sbjct: 10 VRVITLDHPNKHNPFSRTLETSVKDALARANADDSVRAVVVYGGAERSFSAGGDFNEVKQ 69 Query: 106 RTFQDC---YSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQ 162 + + + + + + + + KP IAAV+GYA+G G + A+M D A F Sbjct: 70 LSRSEDIEEWIDRVIDLYQAVLNVNKPTIAAVDGYAIGMGFQFALMFDQRLMASTANFVM 129 Query: 163 PEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEA 222 PE+ G I + G L G S E++ + A LV+++ L++ A Sbjct: 130 PELKHG-IGCSVGAAILGFTHGFSTMQEIIYQCQSLDAPRCVDYRLVNQVVESSALLDAA 188 Query: 223 IQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDD 271 I A +A+ K +VN F L + K + + F D Sbjct: 189 ITQAHVMASYPASAFINTKRAVNKPFIHLLEQTRDASKAVHKAAFQARD 237 >4JSB-A nrPDB Length = 296 Score = 70.1 bits (170), Expect = 9e-13, Method: Compositional matrix adjust. Identities = 57/189 (30%), Positives = 83/189 (43%), Gaps = 21/189 (11%) Query: 44 NSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEM 103 + V I L+RP NA+ + EL + T + AV +V+TG F++G D+ Sbjct: 43 DGEVARITLSRPHRRNAMTGRMWTELARIGHTLPQ--AVRIVVITGEGPTFSSGIDLDMF 100 Query: 104 Q------------------NRTFQ-DCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCE 144 Q N T D + + + R IAAV G+A+G G + Sbjct: 101 QAGKVDGEPTPFTLLARDPNSTAALDQVIASYQEGFLWLRRADIVSIAAVRGHAIGAGFQ 160 Query: 145 LAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAK 204 LA+ CDI + AQ E LG +P GTQ L VG + A+E+ LT I A +A Sbjct: 161 LALSCDIRILSDTAQLCMKEPALGLVPDLTGTQPLVELVGVNRAIELCLTARTIDAAEAA 220 Query: 205 QAGLVSKIF 213 Q L ++ Sbjct: 221 QLRLAERVV 229 >3JU1-A nrPDB Length = 407 Score = 68.2 bits (165), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 54/177 (30%), Positives = 85/177 (48%), Gaps = 21/177 (11%) Query: 47 VGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG-GEKAFAAGADIKEMQN 105 VG++ LN KALNAL ++ + L +++DP + +VL G GEKAF AG D++ + + Sbjct: 52 VGVVTLNVEKALNALDLDMVRAMTVQLNLWKKDPLIACVVLDGSGEKAFCAGGDVRALYH 111 Query: 106 RT--------------FQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDI 151 + F++ Y +L H KPV+ +G +GGG L Sbjct: 112 ASVAAKGQVTEVAKVFFEEEYRLDYLLH-----TYGKPVLVWGDGIVMGGGLGLMAGASH 166 Query: 152 IYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGL 208 E ++ PE+ +G P GG+ L R GK + + + LT ++A DA GL Sbjct: 167 KVVTETSRIAMPEVTIGLYPDVGGSYFLNRMPGK-MGLFLGLTAYHMNAADACYVGL 222 >1XX4-A nrPDB Length = 261 Score = 64.3 bits (155), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 59/262 (22%), Positives = 114/262 (43%), Gaps = 23/262 (8%) Query: 36 IITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKA-F 94 ++ EK+G+ + + +++ P +N+L + E +LE E D ++ ++LT F Sbjct: 6 VLVEKEGE-AGIAVMKFKNP-PVNSLSLEFLTEFVISLEKLENDKSIRGVILTSERPGIF 63 Query: 95 AAGADIKEMQNRTFQDCYSGKFLSHWDHITRI-------KKPVIAAVNGYALGGGCELAM 147 +AG D+ EM R + +W + + +I+A+NG + GGC +A+ Sbjct: 64 SAGLDLMEMYGRN-----PAHYAEYWKAVQELWLRLYLSNLTLISAINGASPAGGCLMAL 118 Query: 148 MCD--IIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQ 205 CD I+ K G E LLG + +G A + G +A + Sbjct: 119 TCDYRIMADNSKYTIGLNESLLGIVAPFWLKDNYVNTIGHRAAERALQLGTLFPPAEALK 178 Query: 206 AGLVSKIFPVETLVEEAIQCAEK---IANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKL 262 GLV ++ P + + +A K I ++S+ + K + A L + + + + Sbjct: 179 VGLVDEVVPEDQVHSKARSVMAKWFTIPDHSR---QLTKSMMRKATADNLIKQREADIQN 235 Query: 263 FYSTFATDDRREGMSAFVEKRK 284 F S + D ++ + ++EK K Sbjct: 236 FTSFISRDSIQKSLHVYLEKLK 257 >4B3J-A nrPDB Length = 736 Score = 63.9 bits (154), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 65/198 (32%), Positives = 94/198 (47%), Gaps = 14/198 (7%) Query: 37 ITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETF-EEDPAVGAIVLTGGEKAFA 95 I K + V L + + N + IE + +A++ E ++ +V+ +K F Sbjct: 22 IQWDKDADGIVTLTMDDPSGSTNVMNEAYIESMGKAVDRLVAEKDSITGVVVASAKKTFF 81 Query: 96 AGADIKEMQNRTFQDCYSGKFLSHWDHITR-------IKKPVIAAVNGYALGGGCELAMM 148 AG D+K M +D G + + I R + KPV+AA+NG ALGGG E+A+ Sbjct: 82 AGGDVKTMIQARPEDA--GDVFNTVETIKRQLRTLETLGKPVVAAINGAALGGGLEIALA 139 Query: 149 CDIIYAGE--KAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLT-GDRISAQDAKQ 205 C A + +Q G PE+ LG +PG GG R R G A VL G R AK+ Sbjct: 140 CHHRIAADVKGSQLGLPEVTLGLLPGGGGVTRTVRMFGIQNAFVSVLAQGTRFKPAKAKE 199 Query: 206 AGLVSKIF-PVETLVEEA 222 GLV ++ VE LV A Sbjct: 200 IGLVDELVATVEELVPAA 217 >3HP0-A nrPDB Length = 267 Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 53/174 (30%), Positives = 74/174 (42%), Gaps = 14/174 (8%) Query: 44 NSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEM 103 +SV I +RP+A N + + LIEE Q L E V +VL G + F GAD +E+ Sbjct: 14 QASVCYITFHRPEANNTINDTLIEECLQVLNQCETS-TVTVVVLEGLPEVFCFGADFQEI 72 Query: 104 QNRTFQDCYSGK--------FLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAG 155 +Q+ G+ W + I+ V G GG DI A Sbjct: 73 ----YQEMKRGRKQASSQEPLYDLWMKLQTGPYVTISHVRGKVNAGGLGFVSATDIAIAD 128 Query: 156 EKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLV 209 + A F E+L G P A L R +G+ A M L IS Q+A + GL+ Sbjct: 129 QTASFSLSELLFGLYP-ACVLPFLIRRIGRQKAHYMTLMTKPISVQEASEWGLI 181 >3M6N-A nrPDB Length = 305 Score = 58.5 bits (140), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 35/99 (35%), Positives = 50/99 (50%), Gaps = 7/99 (7%) Query: 131 IAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAME 190 IA V G ALGGG E A+ C I A E G PE+L PG G + + + LA + Sbjct: 144 IALVQGNALGGGFEAALSCHTIIAEEGVMMGLPEVLFDLFPGMGAYSFMCQRISAHLAQK 203 Query: 191 MVLTGDRISAQDAKQAGLVSKIFP-------VETLVEEA 222 ++L G+ SA+ GLV ++ P VE ++ E+ Sbjct: 204 IMLEGNLYSAEQLLGMGLVDRVVPRGQGVAAVEQVIRES 242 >4HC8-A nrPDB Length = 255 Score = 48.9 bits (115), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 55/196 (28%), Positives = 89/196 (45%), Gaps = 16/196 (8%) Query: 43 KNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKE 102 + S+ +I ++ K +NAL + + LN A++ + D VGA+V+TG + F+ G D+K Sbjct: 11 RKDSIAVISMDDGK-VNALGPAMQQALNAAIDNADRDD-VGALVITGNGRVFSGGFDLKI 68 Query: 103 MQNRTFQ---DCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQ 159 + + Q D G F + + KPV+ A G+A+ G L D A Sbjct: 69 LTSGEVQPAIDMLRGGFELAY-RLLSYPKPVVMACTGHAIAMGAFLLSCGDHRVAAHAYN 127 Query: 160 FGQPEILLG-TIPGAG---GTQRLTR-AVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFP 214 E+ +G TIP A RLTR A ++ + G + A AG + +I Sbjct: 128 IQANEVAIGMTIPYAALEIMKLRLTRSAYQQATGLAKTFFG-----ETALAAGFIDEIAL 182 Query: 215 VETLVEEAIQCAEKIA 230 E +V A + A + A Sbjct: 183 PEVVVSRAEEAAREFA 198 >4ZDC-A nrPDB Length = 300 Score = 48.9 bits (115), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 47/190 (24%), Positives = 77/190 (40%), Gaps = 14/190 (7%) Query: 49 LIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQNRTF 108 +I L P LNAL L + LE + + V ++ + F++GAD K + Sbjct: 41 IIHLINPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGADFKGIAKAQG 100 Query: 109 QDCY-----SGKFLSHW--------DHITRIKKPVIAAVNGYALGGGCELAMMCDIIYA- 154 D + K++S++ D + K +I +NG A+G L +CDI+Y+ Sbjct: 101 DDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVYSI 160 Query: 155 GEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFP 214 +K P LG I G T L G + E ++ + G +SK F Sbjct: 161 NDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISKNFN 220 Query: 215 VETLVEEAIQ 224 + + EA Sbjct: 221 MPSSNAEAFN 230 >5A1W-H nrPDB Length = 511 Score = 28.5 bits (62), Expect = 3.3, Method: Compositional matrix adjust. Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 4/90 (4%) Query: 187 LAMEMVLTGDRISAQDAKQAGLVSKIFP--VETLVEEAI--QCAEKIANNSKIIVAMAKE 242 L M ++ T + +D + L S++ P L E I C + I +I+ +E Sbjct: 64 LYMVLITTKNSNILEDLETLRLFSRVIPEYCRALEENEISEHCFDLIFAFDEIVALGYRE 123 Query: 243 SVNAAFEMTLTEGNKLEKKLFYSTFATDDR 272 +VN A T TE + E+K+F + T +R Sbjct: 124 NVNLAQIRTFTEMDSHEEKVFRAVRETQER 153 >1SJP-A nrPDB Length = 504 Score = 27.3 bits (59), Expect = 7.5, Method: Compositional matrix adjust. Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 10/83 (12%) Query: 192 VLTGDRISAQDAKQAGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMT 251 V T ++I+A A AG S + L+ EA+ +K+ N I V +ES ++ Sbjct: 95 VETKEQIAATAAISAGDQS----IGDLIAEAM---DKVGNEGVITV---EESNTFGLQLE 144 Query: 252 LTEGNKLEKKLFYSTFATDDRRE 274 LTEG + +K F TD R+ Sbjct: 145 LTEGMRFDKGYISGYFVTDPERQ 167 >5I1F-A nrPDB Length = 302 Score = 26.9 bits (58), Expect = 9.5, Method: Compositional matrix adjust. Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 4/79 (5%) Query: 166 LLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAIQC 225 L G PGAGG +LT A+ L E VL D + SK+ ++ VE A++ Sbjct: 226 LRGLKPGAGGELQLTDAIQSLLTDEQVLA----YRYDGTRFDCGSKLGYLKATVEFALRH 281 Query: 226 AEKIANNSKIIVAMAKESV 244 E A+ + ++A E + Sbjct: 282 PEVAADFERYLLARMSEQL 300 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2DUB-A nrPDB 350 3e-97 2HW5-A nrPDB 347 3e-96 5ZAI-A nrPDB 302 1e-82 3H81-A nrPDB 284 3e-77 3MOY-A nrPDB 283 6e-77 2IEX-A nrPDB 282 1e-76 3T88-A nrPDB 282 1e-76 5Z7R-A nrPDB 276 5e-75 4FZW-A nrPDB 273 6e-74 4EML-A nrPDB 265 1e-71 2UZF-A nrPDB 258 2e-69 6OJM-A nrPDB 251 3e-67 1EF9-A nrPDB 249 7e-67 5WYB-B nrPDB 247 5e-66 2PPY-A nrPDB 246 6e-66 5VE2-A nrPDB 233 6e-62 3T8B-A nrPDB 231 4e-61 5JBW-A nrPDB 229 1e-60 4JCS-A nrPDB 228 2e-60 4FZW-C nrPDB 226 7e-60 4JWV-A nrPDB 225 2e-59 2VSU-C nrPDB 222 1e-58 5YLO-A nrPDB 221 4e-58 1NZY-B nrPDB 219 1e-57 4JFC-A nrPDB 216 1e-56 3OME-A nrPDB 213 9e-56 3HE2-A nrPDB 206 7e-54 3HIN-A nrPDB 206 8e-54 2A81-A nrPDB 204 4e-53 3I47-A nrPDB 202 1e-52 5KJP-A nrPDB 202 1e-52 4IZC-A nrPDB 193 9e-50 1XX4-A nrPDB 189 1e-48 3LAO-A nrPDB 189 2e-48 4ZU2-A nrPDB 184 4e-47 3BPT-A nrPDB 180 5e-46 2NP9-A nrPDB 179 2e-45 6IUM-B nrPDB 175 1e-44 5ZRV-A nrPDB 174 5e-44 4Q1J-A nrPDB 173 9e-44 3ZWA-A nrPDB 169 2e-42 2WTB-A nrPDB 168 3e-42 4JSB-A nrPDB 163 9e-41 4J2U-A nrPDB 162 1e-40 5MRE-88 nrPDB 162 1e-40 2D3T-A nrPDB 159 1e-39 4HDT-A nrPDB 152 2e-37 3HP0-A nrPDB 151 3e-37 3JU1-A nrPDB 138 2e-33 4HC8-A nrPDB 135 2e-32 4ZDC-A nrPDB 135 3e-32 4B3J-A nrPDB 128 3e-30 3M6N-A nrPDB 110 6e-25 Sequences not found previously or not previously below threshold: 3BF0-A nrPDB 40 0.001 3SN5-A nrPDB 32 0.26 1QDB-A nrPDB 32 0.44 3U9S-B nrPDB 31 0.61 4KWB-A nrPDB 31 0.68 3RST-A nrPDB 31 0.68 1ON3-A nrPDB 30 1.9 2C8T-A nrPDB 29 2.0 1CHK-A nrPDB 29 2.1 6B5B-F nrPDB 29 2.5 4H27-A nrPDB 29 3.0 1PWH-A nrPDB 29 3.1 2NVK-X nrPDB 28 3.5 2YJN-B nrPDB 28 4.5 4Q28-A nrPDB 28 4.8 3QWD-A nrPDB 28 4.9 1SKF-A nrPDB 28 5.1 6MZL-P nrPDB 28 5.5 3BEO-A nrPDB 28 5.8 1BH8-B nrPDB 28 5.8 2OVL-A nrPDB 28 5.9 2YV2-A nrPDB 28 6.0 2WWR-A nrPDB 28 6.2 4WHX-A nrPDB 28 6.5 2GQD-A nrPDB 28 7.0 >2DUB-A nrPDB Length = 261 Score = 350 bits (899), Expect = 3e-97, Method: Composition-based stats. Identities = 261/261 (100%), Positives = 261/261 (100%) Query: 30 GANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG 89 GANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG Sbjct: 1 GANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG 60 Query: 90 GEKAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMC 149 GEKAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMC Sbjct: 61 GEKAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMC 120 Query: 150 DIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLV 209 DIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLV Sbjct: 121 DIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLV 180 Query: 210 SKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFAT 269 SKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFAT Sbjct: 181 SKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFAT 240 Query: 270 DDRREGMSAFVEKRKANFKDH 290 DDRREGMSAFVEKRKANFKDH Sbjct: 241 DDRREGMSAFVEKRKANFKDH 261 >2HW5-A nrPDB Length = 286 Score = 347 bits (890), Expect = 3e-96, Method: Composition-based stats. Identities = 237/267 (88%), Positives = 256/267 (95%) Query: 24 FRRFASGANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVG 83 F+ ASGANF+YII EK+GKN++VGLIQLNRPKALNALC+GLI+ELNQAL+ FEEDPAVG Sbjct: 20 FQSMASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKIFEEDPAVG 79 Query: 84 AIVLTGGEKAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGC 143 AIVLTGG+KAFAAGADIKEMQN +FQDCYS KFL HWDH+T++KKPVIAAVNGYA GGGC Sbjct: 80 AIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGC 139 Query: 144 ELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDA 203 ELAMMCDIIYAGEKAQF QPEIL+GTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDA Sbjct: 140 ELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDA 199 Query: 204 KQAGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLF 263 KQAGLVSKI PVETLVEEAIQCAEKIA+NSKI+VAMAKESVNAAFEMTLTEG+KLEKKLF Sbjct: 200 KQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLF 259 Query: 264 YSTFATDDRREGMSAFVEKRKANFKDH 290 YSTFATDDR+EGM+AFVEKRKANFKD Sbjct: 260 YSTFATDDRKEGMTAFVEKRKANFKDQ 286 >5ZAI-A nrPDB Length = 259 Score = 302 bits (774), Expect = 1e-82, Method: Composition-based stats. Identities = 122/261 (46%), Positives = 165/261 (63%), Gaps = 5/261 (1%) Query: 32 NFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGE 91 F+ I T+K+G ++ I LNRP LNAL L+EEL++A+ E DP + I++TG Sbjct: 2 EFETIETKKEG---NLFWITLNRPDKLNALNAKLLEELDRAVSQAESDPEIRVIIITGKG 58 Query: 92 KAFAAGADIKEMQNRTFQDCYSG--KFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMC 149 KAF AGADI + T + + K D I + KP IA +NGYALGGG ELA+ C Sbjct: 59 KAFCAGADITQFNQLTPAEAWKFSKKGREIMDKIEALSKPTIAMINGYALGGGLELALAC 118 Query: 150 DIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLV 209 DI A E+AQ G PEI LG PG GGTQRLTR +GK A+EM++TGDRI +DA++ GLV Sbjct: 119 DIRIAAEEAQLGLPEINLGIYPGYGGTQRLTRVIGKGRALEMMMTGDRIPGKDAEKYGLV 178 Query: 210 SKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFAT 269 +++ P+ L +E + AEKIA S I +A+ KE VN + L G LE + F+T Sbjct: 179 NRVVPLANLEQETRKLAEKIAKKSPISLALIKEVVNRGLDSPLLSGLALESVGWGVVFST 238 Query: 270 DDRREGMSAFVEKRKANFKDH 290 +D++EG+SAF+EKR+ FK Sbjct: 239 EDKKEGVSAFLEKREPTFKGK 259 >3H81-A nrPDB Length = 278 Score = 284 bits (727), Expect = 3e-77, Method: Composition-based stats. Identities = 129/259 (49%), Positives = 183/259 (70%), Gaps = 3/259 (1%) Query: 32 NFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGE 91 ++ I+ E ++ VG+I LNRP+ALNAL + ++ E+ A ++DP +GAI++TG Sbjct: 23 TYETILVE---RDQRVGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITGSA 79 Query: 92 KAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDI 151 KAFAAGADIKEM + TF D ++ F + W + ++ P IAAV GYALGGGCELAMMCD+ Sbjct: 80 KAFAAGADIKEMADLTFADAFTADFFATWGKLAAVRTPTIAAVAGYALGGGCELAMMCDV 139 Query: 152 IYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSK 211 + A + A+FGQPEI LG +PG GG+QRLTRA+GK+ AM+++LTG + A +A+++GLVS+ Sbjct: 140 LIAADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSR 199 Query: 212 IFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDD 271 + P + L+ EA A I+ S MAKE+VN AFE +L+EG E++LF+S FAT+D Sbjct: 200 VVPADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATED 259 Query: 272 RREGMSAFVEKRKANFKDH 290 + EGM+AF+EKR F Sbjct: 260 QSEGMAAFIEKRAPQFTHR 278 >3MOY-A nrPDB Length = 263 Score = 283 bits (724), Expect = 6e-77, Method: Composition-based stats. Identities = 128/263 (48%), Positives = 175/263 (66%) Query: 28 ASGANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVL 87 G+ Y + VGLI+L+RP ALNAL L E+ A F+ D +GAIV+ Sbjct: 1 GPGSMTTYTTIATSRPVAGVGLIRLDRPDALNALNQTLEAEVLDAARDFDADLEIGAIVV 60 Query: 88 TGGEKAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAM 147 TG E+AFAAGADI EM T LS WD +T+++KP++AAV GYALGGGCELAM Sbjct: 61 TGSERAFAAGADIAEMVTLTPHQARERNLLSGWDSLTQVRKPIVAAVAGYALGGGCELAM 120 Query: 148 MCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAG 207 +CD++ A + A+FGQPEI LG +PG GGTQRLTRAVGK+ AM++ LTG ++A++A++ G Sbjct: 121 LCDLVIAADTARFGQPEITLGILPGLGGTQRLTRAVGKAKAMDLCLTGRSLTAEEAERVG 180 Query: 208 LVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTF 267 LVS+I P L++EA+ A++IA S+ K+++N AFE L+ G + E+ FY+ F Sbjct: 181 LVSRIVPAADLLDEALAVAQRIARMSRPAGRAVKDAINEAFERPLSAGMRYERDAFYAMF 240 Query: 268 ATDDRREGMSAFVEKRKANFKDH 290 T D+ EGM+AF+EKR F D Sbjct: 241 DTHDQTEGMTAFLEKRTPEFTDR 263 >2IEX-A nrPDB Length = 272 Score = 282 bits (722), Expect = 1e-76, Method: Composition-based stats. Identities = 88/263 (33%), Positives = 132/263 (50%), Gaps = 8/263 (3%) Query: 32 NFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG-G 90 +++ II E + + I +NRP+ NA + E+ A +D +G I+LTG G Sbjct: 10 DYEDIIYETY---NGIAKITINRPEVHNAFRPKTVNEMIDAFTKARDDSNIGVIILTGAG 66 Query: 91 EKAFAAGADIKEMQNRTFQDCYSGKFLSHWDH---ITRIKKPVIAAVNGYALGGGCELAM 147 KAF +G D K + + L+ D I I KPVIA V GYA+GGG L + Sbjct: 67 GKAFCSGGDQKVRGHGGYVGEDEIPRLNVLDLQRLIRVIPKPVIAMVAGYAIGGGHVLHV 126 Query: 148 MCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAG 207 +CD+ A + A FGQ +G+ G G L R VG A E+ + +AQ+A + G Sbjct: 127 VCDLTIAADNAIFGQTGPKVGSFDGGYGAGYLARIVGHKKAREIWYLCRQYTAQEALEMG 186 Query: 208 LVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTF 267 LV+K+ P+E L EE ++ A++I S + K + NA + L +L + Sbjct: 187 LVNKVVPLEQLEEETVKWAQEILEKSPTAIRFLKAAFNADSD-GLAGIQQLAGDATLLFY 245 Query: 268 ATDDRREGMSAFVEKRKANFKDH 290 T++ +EGM AF EKRK +F Sbjct: 246 TTEEAKEGMRAFKEKRKPDFSQF 268 >3T88-A nrPDB Length = 289 Score = 282 bits (721), Expect = 1e-76, Method: Composition-based stats. Identities = 85/279 (30%), Positives = 133/279 (47%), Gaps = 13/279 (4%) Query: 15 LLSPVRCPEFRRFASGANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALE 74 L +PV E+ + G F+ I EK + I +NRP+ NA ++E+ QAL Sbjct: 13 LYAPV---EWHDCSEG--FEDIRYEKS--TDGIAKITINRPQVRNAFRPLTVKEMIQALA 65 Query: 75 TFEEDPAVGAIVLTGGE-KAFAAGADIKEMQNRTFQDCYSG----KFLSHWDHITRIKKP 129 D +G I+LTG KAF +G D K + SG L I KP Sbjct: 66 DARYDDNIGVIILTGAGDKAFCSGGDQKVRGDYGGYKDDSGVHHLNVLDFQRQIRTCPKP 125 Query: 130 VIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAM 189 V+A V GY++GGG L MMCD+ A + A FGQ +G+ G G + R VG+ A Sbjct: 126 VVAMVAGYSIGGGHVLHMMCDLTIAADNAIFGQTGPKVGSFDGGWGASYMARIVGQKKAR 185 Query: 190 EMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFE 249 E+ + A+ A GLV+ + P+ L +E ++ ++ NS + + K ++NA + Sbjct: 186 EIWFLCRQYDAKQALDMGLVNTVVPLADLEKETVRWCREMLQNSPMALRCLKAALNADCD 245 Query: 250 MTLTEGNKLEKKLFYSTFATDDRREGMSAFVEKRKANFK 288 +L + T++ +EG +AF +KR+ +F Sbjct: 246 -GQAGLQELAGNATMLFYMTEEGQEGRNAFNQKRQPDFS 283 >5Z7R-A nrPDB Length = 267 Score = 276 bits (707), Expect = 5e-75, Method: Composition-based stats. Identities = 104/256 (40%), Positives = 158/256 (61%), Gaps = 6/256 (2%) Query: 32 NFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGE 91 +I EK+GK V ++ +NRPKALNAL + ++E++ + E D V A++LTG Sbjct: 2 ELNNVILEKEGK---VAVVTINRPKALNALNSDTLKEMDYVIGEIENDSEVLAVILTGAG 58 Query: 92 -KAFAAGADIKEMQNRTFQDCYSGKFLSH--WDHITRIKKPVIAAVNGYALGGGCELAMM 148 K+F AGADI EM+ + L + + + ++KPVIAAVNG+ALGGGCE+AM Sbjct: 59 EKSFVAGADISEMKEMNTIEGRKFGILGNKVFRRLELLEKPVIAAVNGFALGGGCEIAMS 118 Query: 149 CDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGL 208 CDI A A+FGQPE+ LG PG GGTQRL+R VG +A +++ T I A +A + GL Sbjct: 119 CDIRIASSNARFGQPEVGLGITPGFGGTQRLSRLVGMGMAKQLIFTAQNIKADEALRIGL 178 Query: 209 VSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFA 268 V+K+ L+ A + A KI +N+ + V ++K+++N + + E + F F+ Sbjct: 179 VNKVVEPSELMNTAKEIANKIVSNAPVAVKLSKQAINRGMQCDIDTALAFESEAFGECFS 238 Query: 269 TDDRREGMSAFVEKRK 284 T+D+++ M+AF+EKRK Sbjct: 239 TEDQKDAMTAFIEKRK 254 >4FZW-A nrPDB Length = 258 Score = 273 bits (699), Expect = 6e-74, Method: Composition-based stats. Identities = 118/248 (47%), Positives = 163/248 (65%) Query: 43 KNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKE 102 + V L+ LNRP A NAL N L+ +L LE D ++ V+TG + FAAGAD+ E Sbjct: 11 RQQRVLLLTLNRPAARNALNNALLMQLVNELEAAATDTSISVCVITGNARFFAAGADLNE 70 Query: 103 MQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQ 162 M + + W + KP+IAAVNGYALG GCELA++CD++ AGE A+FG Sbjct: 71 MAEKDLAATLNDTRPQLWARLQAFNKPLIAAVNGYALGAGCELALLCDVVVAGENARFGL 130 Query: 163 PEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEA 222 PEI LG +PGAGGTQRL R+VGKSLA +MVL+G+ I+AQ A+QAGLVS +FP + +E A Sbjct: 131 PEITLGIMPGAGGTQRLIRSVGKSLASKMVLSGESITAQQAQQAGLVSDVFPSDLTLEYA 190 Query: 223 IQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGMSAFVEK 282 +Q A K+A +S + + AK+++ + E+ L G E++LF AT+DR EG+SAF++K Sbjct: 191 LQLASKMARHSPLALQAAKQALRQSQEVALQAGLAQERQLFTLLAATEDRHEGISAFLQK 250 Query: 283 RKANFKDH 290 R +FK Sbjct: 251 RTPDFKGR 258 >4EML-A nrPDB Length = 275 Score = 265 bits (678), Expect = 1e-71, Method: Composition-based stats. Identities = 82/267 (30%), Positives = 126/267 (47%), Gaps = 13/267 (4%) Query: 33 FQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEK 92 + I+ K G + I +NRP NA + EL A ED +G ++LTG Sbjct: 9 YDDILYYKAG---GIAKIVINRPHKRNAFRPQTVFELYDAFCNAREDNRIGVVLLTGAGP 65 Query: 93 A------FAAGADIKEMQNRTFQDCYSGKFLSHWDH---ITRIKKPVIAAVNGYALGGGC 143 F +G D + D L+ D I + K VIA V GYA+GGG Sbjct: 66 HSDGKYAFCSGGDQSVRGEGGYIDDQGTPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGH 125 Query: 144 ELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDA 203 L ++CD+ A + A FGQ +G+ G G+ L R VG+ A E+ + SAQ+A Sbjct: 126 VLHLVCDLTIAADNAIFGQTGPKVGSFDGGFGSSYLARIVGQKKAREIWYLCRQYSAQEA 185 Query: 204 KQAGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLF 263 ++ G+V+ + PV+ L EE IQ A++I + S + + K + NA + +L Sbjct: 186 ERMGMVNTVVPVDRLEEEGIQWAKEILSKSPLAIRCLKAAFNADCD-GQAGLQELAGNAT 244 Query: 264 YSTFATDDRREGMSAFVEKRKANFKDH 290 + T++ EG AF+EKR +F + Sbjct: 245 LLYYMTEEGSEGKQAFLEKRPPDFSQY 271 >2UZF-A nrPDB Length = 273 Score = 258 bits (660), Expect = 2e-69, Method: Composition-based stats. Identities = 80/273 (29%), Positives = 127/273 (46%), Gaps = 13/273 (4%) Query: 23 EFRRFASGANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAV 82 ++ +Y E + + +NRP+ NA + E+ A +D V Sbjct: 5 QWETLREYDEIKYEFYE------GIAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNV 58 Query: 83 GAIVLTGGEK-AFAAGADIKEMQNRTFQDCYSGKFLSHWDH---ITRIKKPVIAAVNGYA 138 IVLTG AF +G D K+ + + L+ D I I KPVIA V GYA Sbjct: 59 SVIVLTGEGDLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYA 118 Query: 139 LGGGCELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRI 198 +GGG L ++CD+ A + A FGQ +G+ G+ L R VG A E+ + Sbjct: 119 VGGGNVLNVVCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQY 178 Query: 199 SAQDAKQAGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFE-MTLTEGNK 257 +AQ+A GLV+ + P+E + +E +Q ++I +S + K ++NA + + + Sbjct: 179 NAQEALDMGLVNTVVPLEKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMA 238 Query: 258 LEKKLFYSTFATDDRREGMSAFVEKRKANFKDH 290 + L Y + TD+ +EG AF EKR +F Sbjct: 239 GDATLLY--YTTDEAKEGRDAFKEKRDPDFDQF 269 >6OJM-A nrPDB Length = 286 Score = 251 bits (640), Expect = 3e-67, Method: Composition-based stats. Identities = 79/269 (29%), Positives = 130/269 (48%), Gaps = 15/269 (5%) Query: 32 NFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG-- 89 ++ I + K + V I NRP+ NA EL A EDP++G ++L+G Sbjct: 17 EYEDITYK---KCNGVARIAFNRPEIRNAFRPKTTSELYDAFYDAYEDPSIGVVLLSGEG 73 Query: 90 -----GEKAFAAGADIKEMQNRTFQDCYSGKFLSHWD---HITRIKKPVIAAVNGYALGG 141 G AF +G D K ++ + L+ + I + K VIA V G+A+GG Sbjct: 74 PSPKDGGWAFCSGGDQKARGHQGYVGEDGRHRLNILEVQRLIRFMPKVVIAVVPGWAVGG 133 Query: 142 GCELAMMCDIIYAG-EKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISA 200 G L ++CD+ A E A F Q + + + G G+ L + VG+ A E+ G SA Sbjct: 134 GHSLHVVCDLTLASKEHAIFKQTDADVTSFDGGYGSAYLAKMVGQKKAREIFFLGRNYSA 193 Query: 201 QDAKQAGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEK 260 Q+A + G+V+K+ P L + A + A++I S + M K ++N + + Sbjct: 194 QEAFEMGMVNKVVPHAELEDTAYEWAQEILAKSPTSIRMLKFAMN-LTDDGMVGQQVFAG 252 Query: 261 KLFYSTFATDDRREGMSAFVEKRKANFKD 289 + + TD+ +EG +AF+EKRK +F + Sbjct: 253 EATRLAYMTDEAKEGRNAFLEKRKPDFGE 281 >1EF9-A nrPDB Length = 261 Score = 249 bits (637), Expect = 7e-67, Method: Composition-based stats. Identities = 79/264 (29%), Positives = 126/264 (47%), Gaps = 9/264 (3%) Query: 32 NFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLT--G 89 ++QY+ K V +I+ N + LNAL I++L QAL P + I+L Sbjct: 2 SYQYVNVVTINK---VAVIEFNYGRKLNALSKVFIDDLMQALSDLNR-PEIRCIILRAPS 57 Query: 90 GEKAFAAGADIKEMQNRTFQD-CYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMM 148 G K F+AG DI E+ + Y I + KP+I+ V G GG E+ M Sbjct: 58 GSKVFSAGHDIHELPSGGRDPLSYDDPLRQITRMIQKFPKPIISMVEGSVWGGAFEMIMS 117 Query: 149 CDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGL 208 D+I A + F + LG G LTR G + E++ T I+AQ A G+ Sbjct: 118 SDLIIAASTSTFSMTPVNLGVPYNLVGIHNLTRDAGFHIVKELIFTASPITAQRALAVGI 177 Query: 209 VSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEK--KLFYST 266 ++ + VE L + +Q A I+ + + +A+ KE + E ++ E+ + + Sbjct: 178 LNHVVEVEELEDFTLQMAHHISEKAPLAIAVIKEELRVLGEAHTMNSDEFERIQGMRRAV 237 Query: 267 FATDDRREGMSAFVEKRKANFKDH 290 + ++D +EGM+AF+EKRK NF H Sbjct: 238 YDSEDYQEGMNAFLEKRKPNFVGH 261 >5WYB-B nrPDB Length = 280 Score = 247 bits (630), Expect = 5e-66, Method: Composition-based stats. Identities = 83/264 (31%), Positives = 129/264 (48%), Gaps = 4/264 (1%) Query: 29 SGANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLT 88 ++F K+ LI +N P A N + L Q +E D + A+V+T Sbjct: 9 KASSFDDTHKLTVEKHGHTALITINHPPA-NTWDRDSLIGLRQLIEHLNRDDDIYALVVT 67 Query: 89 G-GEKAFAAGADIKEMQN--RTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCEL 145 G G K F+AGAD+ + + + +F ++ + + IAA+NGYA+GGG E Sbjct: 68 GQGPKFFSAGADLNMFADGDKARAREMARRFGEAFEALRDFRGVSIAAINGYAMGGGLEC 127 Query: 146 AMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQ 205 A+ CDI A +AQ PE +G +P AGGTQ L VG+ A M+L +R+ A+ A + Sbjct: 128 ALACDIRIAERQAQMALPEAAVGLLPCAGGTQALPWLVGEGWAKRMILCNERVDAETALR 187 Query: 206 AGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYS 265 GLV ++ A+ A K+A S + + K + A E E++ F Sbjct: 188 IGLVEQVVDSGEARGAALLLAAKVARQSPVAIRTIKPLIQGARERAPNTWLPEERERFVD 247 Query: 266 TFATDDRREGMSAFVEKRKANFKD 289 F D REG++AF+EKR +++ Sbjct: 248 LFDAQDTREGVNAFLEKRDPKWRN 271 >2PPY-A nrPDB Length = 265 Score = 246 bits (629), Expect = 6e-66, Method: Composition-based stats. Identities = 84/251 (33%), Positives = 140/251 (55%), Gaps = 5/251 (1%) Query: 43 KNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAI-VLTGGEKAFAAGADIK 101 K + I L+ K+ N+ +E N A++ DP + + V++ K F+AGADI Sbjct: 15 KEDGIAEIHLHINKS-NSYDLEFYKEFNAAIDDIRFDPDIKVVIVMSDVPKFFSAGADIN 73 Query: 102 EMQNRTFQDCYSGKFL--SHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKA- 158 +++ + D I R + IA + G+ +GGG E+A+ CD+ + G++A Sbjct: 74 FLRSADPRFKTQFCLFCNETLDKIARSPQVYIACLEGHTVGGGLEMALACDLRFMGDEAG 133 Query: 159 QFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETL 218 + G PE+ LG + G GGTQRL R +G S A++M +TG+ I+ Q+A + GLV+++FP Sbjct: 134 KIGLPEVSLGVLAGTGGTQRLARLIGYSRALDMNITGETITPQEALEIGLVNRVFPQAET 193 Query: 219 VEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGMSA 278 E + A K+AN++ V+ K ++ EM L + E +L F ++D +EG+SA Sbjct: 194 RERTREYARKLANSATYAVSNIKLAIMNGKEMPLNVAIRYEGELQNLLFRSEDAKEGLSA 253 Query: 279 FVEKRKANFKD 289 F+EKR+ N+K Sbjct: 254 FLEKRQPNWKG 264 >5VE2-A nrPDB Length = 275 Score = 233 bits (595), Expect = 6e-62, Method: Composition-based stats. Identities = 73/244 (29%), Positives = 130/244 (53%), Gaps = 1/244 (0%) Query: 44 NSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEM 103 N+ V + +NRP+ NAL L L LE D + A++LT F AG D+ + Sbjct: 32 NNRVLSLTINRPELKNALNRELYAALADELERSNHDDQIRAVLLTANGDTFTAGNDLDDF 91 Query: 104 QNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQP 163 N ++ + + I+ + P++ AVNG A+G G + + CD++YA + A+F P Sbjct: 92 INP-VEESGTPSVIRFLKAISECETPIVVAVNGPAIGVGLTMLLHCDMVYASKSARFRAP 150 Query: 164 EILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAI 223 +G +P A + L AVG++ A +++L G + A++A AGLV+++F + LV E++ Sbjct: 151 FTHVGLVPEAASSLLLPLAVGQAWANDLMLAGRILDAREALSAGLVTRVFEDDVLVAESL 210 Query: 224 QCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGMSAFVEKR 283 + AE++A+ + V +K + + + K E +F A+ + +E ++AF EKR Sbjct: 211 KIAEQVASLAPNSVKQSKRLIRGVNKEEVQAQMKREGVIFAEQLASAEFKESVAAFFEKR 270 Query: 284 KANF 287 +F Sbjct: 271 APHF 274 >3T8B-A nrPDB Length = 334 Score = 231 bits (588), Expect = 4e-61, Method: Composition-based stats. Identities = 74/284 (26%), Positives = 117/284 (41%), Gaps = 22/284 (7%) Query: 26 RFASGANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAI 85 R G + IT + + + + NRP+ NA ++EL + L+ P VG + Sbjct: 46 RLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVV 105 Query: 86 VLTG-------GEKAFAAGADIKEMQNRTFQ-------------DCYSGKFLSHWDHITR 125 +LTG G AF +G D + +Q L I Sbjct: 106 LLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRF 165 Query: 126 IKKPVIAAVNGYALGGGCELAMMCDIIYAGEK-AQFGQPEILLGTIPGAGGTQRLTRAVG 184 + K VI VNG+A GGG L ++CD+ A + A+F Q + +G+ G G+ L R VG Sbjct: 166 MPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVG 225 Query: 185 KSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESV 244 + A E+ G +A+ Q G V+ + L +Q A +I S M K + Sbjct: 226 QKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAF 285 Query: 245 NAAFEMTLTEGNKLEKKLFYSTFATDDRREGMSAFVEKRKANFK 288 N + L + + TD+ EG AF++KR ++ Sbjct: 286 N-LLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWS 328 >5JBW-A nrPDB Length = 260 Score = 229 bits (584), Expect = 1e-60, Method: Composition-based stats. Identities = 87/254 (34%), Positives = 130/254 (51%), Gaps = 3/254 (1%) Query: 40 KKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGE-KAFAAGA 98 K + + ++ NA+ +++EL + + V A+V+TG KAF AGA Sbjct: 7 KVDARGPIEIWTIDGESRRNAISRAMLKELGELVTRVSSSRDVRAVVITGAGDKAFCAGA 66 Query: 99 DIKEMQNRTFQD--CYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGE 156 D+KE + + + I + IAA+NG ALGGG ELA+ CD+ A Sbjct: 67 DLKERATMAEDEVRAFLDGLRRTFRAIEKSDCVFIAAINGAALGGGTELALACDLRVAAP 126 Query: 157 KAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVE 216 A+ G E+ LG IPG GGTQRL R VG A +++LT RI+A +A GL +++ P Sbjct: 127 AAELGLTEVKLGIIPGGGGTQRLARLVGPGRAKDLILTARRINAAEAFSVGLANRLAPEG 186 Query: 217 TLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGM 276 L+ A AE + N+ I VA AK +++ + L + LE + + T+DR EG+ Sbjct: 187 HLLAVAYGLAESVVENAPIAVATAKHAIDEGTGLELDDALALELRKYEEILKTEDRLEGL 246 Query: 277 SAFVEKRKANFKDH 290 AF EKR +K Sbjct: 247 RAFAEKRAPVYKGR 260 >4JCS-A nrPDB Length = 286 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 69/267 (25%), Positives = 122/267 (45%), Gaps = 5/267 (1%) Query: 29 SGANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLT 88 FQ + T ++VG I++NR N L +L LE +D + +VLT Sbjct: 16 ENLYFQSMDTLDFEVVNNVGWIRMNRAAKHNPFDAELRADLMTVLERVRDDADIRVLVLT 75 Query: 89 GGEKAFAAGADIKEMQN-----RTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGC 143 +F AG ++ +++ + L + + +PVIAAV+G A G G Sbjct: 76 SHPGSFCAGGNLHVLRDNLDSGPAYWQQRIKTGLRFIHDMLNLGRPVIAAVDGPAFGAGF 135 Query: 144 ELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDA 203 L++ DI+ A +A+F + LG +P G L RAVG A E++ + + A++A Sbjct: 136 ALSLTADIVLASPRARFSMAYLRLGLVPDLGALYLLPRAVGLQRAKELMFSTRELDAEEA 195 Query: 204 KQAGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLF 263 + GLV ++ E L + A + AE + + +A+ K ++N + + LE Sbjct: 196 HRLGLVMEVHESEALEQRAREIAESLVQAAPTALALTKAALNVSLDSDEQTMFSLEAASQ 255 Query: 264 YSTFATDDRREGMSAFVEKRKANFKDH 290 + F+T + R + A + K+ F+ Sbjct: 256 AAAFSTKEPRAAIEALLSKQPPPFRGF 282 >4FZW-C nrPDB Length = 274 Score = 226 bits (577), Expect = 7e-60, Method: Composition-based stats. Identities = 78/256 (30%), Positives = 123/256 (48%), Gaps = 6/256 (2%) Query: 41 KGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADI 100 V + LNRP+ LN+ + + +L + L+ E D + ++LTG + F AG D+ Sbjct: 19 SHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDL 78 Query: 101 KEM------QNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYA 154 + + + ++ KPVI AVNG A G G LA+ DI+ A Sbjct: 79 NDRNVDPTGPAPDLGMSVERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIA 138 Query: 155 GEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFP 214 A+F LG IP GGT L R G++ AM + L G+++SA+ A + G++ ++ Sbjct: 139 ARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVD 198 Query: 215 VETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRRE 274 ETL + A Q A +A + + K+++N+A TL LE+ + D RE Sbjct: 199 DETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAGRSADYRE 258 Query: 275 GMSAFVEKRKANFKDH 290 G+SAF+ KR F Sbjct: 259 GVSAFLAKRSPQFTGK 274 >4JWV-A nrPDB Length = 278 Score = 225 bits (573), Expect = 2e-59, Method: Composition-based stats. Identities = 87/265 (32%), Positives = 131/265 (49%), Gaps = 7/265 (2%) Query: 27 FASGANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIV 86 F S A+ + I V ++LNRP+ LNA+ + + L A + + A+V Sbjct: 20 FQSMADIDFRI------EGHVAHVRLNRPQGLNAITQEMDDLLLDAWTEVNANSDIWAVV 73 Query: 87 LTG-GEKAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCEL 145 L+ GEKAF GAD+ R + G + KKP++AAV G+ +GGG EL Sbjct: 74 LSAEGEKAFCIGADVSGGAERKTRMALGGGLTGIGGPLVTCKKPMVAAVQGFCVGGGFEL 133 Query: 146 AMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQ 205 AM DII A + AQFG PE +G I G R R + +A++++LTG+RI A +A+ Sbjct: 134 AMCADIIVAADTAQFGLPETKVGIIGECGVVHRAMRQLPYHIALQLILTGERIKADEARH 193 Query: 206 AGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYS 265 GLV+++ P L E A++ A K+ S + V AK + L + Sbjct: 194 YGLVNEVVPFAELEEAALRWASKLNAASPLAVQAAKAAALGRLGHPLEVALMTRFEPIEE 253 Query: 266 TFATDDRREGMSAFVEKRKANFKDH 290 AT+D++EG A E+RK + Sbjct: 254 YAATEDKKEGERAAGERRKPVWTGK 278 >2VSU-C nrPDB Length = 275 Score = 222 bits (567), Expect = 1e-58, Method: Composition-based stats. Identities = 73/256 (28%), Positives = 113/256 (44%), Gaps = 9/256 (3%) Query: 38 TEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAG 97 T K + + LNRP+ NA+ L E+ LET E+DPA G +VLTG +A+ AG Sbjct: 10 TVKVEIEDGIAFVILNRPEKRNAMSPTLNREMIDVLETLEQDPAAGVLVLTGAGEAWTAG 69 Query: 98 ADIKEM-------QNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCD 150 D+KE + W + KP IA VNG+ GGG + CD Sbjct: 70 MDLKEYFREVDAGPEILQEKIRREASQWQWKLLRMYAKPTIAMVNGWCFGGGFAPLVACD 129 Query: 151 IIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVS 210 + ++A FG EI G PG ++ + VG ++ ++TG Q A + GLV+ Sbjct: 130 LAICADEATFGLSEINWGIPPGNLVSKAMADTVGHRQSLYYIMTGKTFGGQKAAEMGLVN 189 Query: 211 KIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNK--LEKKLFYSTFA 268 + P+ L E I+ A + + +++ AK E+T + K Sbjct: 190 ESVPLAQLREVTIELARNLLEKNPVVLRAAKHGFKRCRELTWEQNEDYLYAKLDQSRLLD 249 Query: 269 TDDRREGMSAFVEKRK 284 T R +GM F++ + Sbjct: 250 TGGREQGMKQFLDDKS 265 >5YLO-A nrPDB Length = 271 Score = 221 bits (562), Expect = 4e-58, Method: Composition-based stats. Identities = 74/253 (29%), Positives = 115/253 (45%), Gaps = 5/253 (1%) Query: 43 KNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKE 102 + + + LNRP+ NAL +E L+ L+ E DPAV A+VL G ++F AGAD+ E Sbjct: 11 VEAGIAWLVLNRPQQRNALDIPTLEALHVRLDACERDPAVRAVVLGGSGRSFCAGADLAE 70 Query: 103 MQNRTFQD-----CYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEK 157 + ++ + + + KP +AAVNG A+G G +LA+ CD A Sbjct: 71 WAAAEARGELESYGWTEAAHALMGRLHALDKPTVAAVNGSAVGAGMDLALCCDFRIAAAS 130 Query: 158 AQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVET 217 A+F + P AG + L R +G A ++ + SA+ A AGLV ++ E Sbjct: 131 ARFKAGYTGMAYCPDAGASWHLPRLLGSEAAKRLLFLDEAWSAERALGAGLVGEVVADEH 190 Query: 218 LVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGMS 277 LVE A ++A+ A K + +L E + E+ ++D E + Sbjct: 191 LVEAVGAFAARLASGPTFAFAQTKRLLRDGAGRSLAEQLRAEQAAGLLCGRSEDAAEALR 250 Query: 278 AFVEKRKANFKDH 290 A EKR F Sbjct: 251 AVAEKRSPQFSGR 263 >1NZY-B nrPDB Length = 269 Score = 219 bits (559), Expect = 1e-57, Method: Composition-based stats. Identities = 72/251 (28%), Positives = 123/251 (49%), Gaps = 7/251 (2%) Query: 43 KNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKE 102 V I + P+ NAL ++E+ AL EED +VGA+++TG E AF AG ++E Sbjct: 9 VEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLRE 68 Query: 103 MQNRTFQDCYSGKFL--SHWDH-----ITRIKKPVIAAVNGYALGGGCELAMMCDIIYAG 155 + F + W H I R+K+PV+AA+NG A GGG +++ D+ Sbjct: 69 IPLDKGVAGVRDHFRIAALWWHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICA 128 Query: 156 EKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPV 215 + A+F +G + L R VG AME++LT + ++AK GLVS+++P Sbjct: 129 DSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMELMLTDRTLYPEEAKDWGLVSRVYPK 188 Query: 216 ETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREG 275 + E A + A ++A + MAKE +A + + E + E + ++ Sbjct: 189 DEFREVAWKVARELAAAPTHLQVMAKERFHAGWMQPVEECTEFEIQNVIASVTHPHFMPC 248 Query: 276 MSAFVEKRKAN 286 ++ F++ +A+ Sbjct: 249 LTRFLDGHRAD 259 >4JFC-A nrPDB Length = 281 Score = 216 bits (549), Expect = 1e-56, Method: Composition-based stats. Identities = 77/254 (30%), Positives = 126/254 (49%), Gaps = 5/254 (1%) Query: 40 KKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGAD 99 K ++ L+ P+ NAL + +AL E +P + ++V+TG F AG + Sbjct: 28 KSTSEGQTLILTLSNPEFRNALGPEIYAAGIEALNAAENNPEIRSVVITGEGAVFCAGGN 87 Query: 100 IKEMQNRTFQ----DCYSGKFLSHW-DHITRIKKPVIAAVNGYALGGGCELAMMCDIIYA 154 ++ +Q + S + L +W D I KPVIAAV G A G G LA+ CD + A Sbjct: 88 LQRLQANRREAPEVQAQSIEGLHNWIDSIRTYPKPVIAAVEGAAAGAGFSLALACDFVVA 147 Query: 155 GEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFP 214 A F +G P GG+ L R++ ++LA E+++ G+RISAQ GLV+K+ Sbjct: 148 ASNAVFVMSYSTVGLSPDGGGSWSLARSLPRALASELLMGGERISAQRLHDLGLVNKVAS 207 Query: 215 VETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRRE 274 + EA++ A ++ + +A KE +N A TL++ E+ F + E Sbjct: 208 AGDALSEALRMAGQLNARAPNALASIKELINEASSNTLSQQLACERDHFVRNLHHSNGGE 267 Query: 275 GMSAFVEKRKANFK 288 G++AF+ KR ++ Sbjct: 268 GIAAFLGKRTPQYR 281 >3OME-A nrPDB Length = 282 Score = 213 bits (542), Expect = 9e-56, Method: Composition-based stats. Identities = 65/223 (29%), Positives = 109/223 (48%), Gaps = 9/223 (4%) Query: 35 YIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAF 94 ++ G S+ I LNRP+A NA L++EL+ A ED V I+L K F Sbjct: 21 SMVYIDYGVADSIATITLNRPEAANAQNPELLDELDAAWTRAAEDNEVKVIILRANGKHF 80 Query: 95 AAGADIK---EMQNRTFQDCY----SGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAM 147 +AG D++ E+ + + + ++L + + KP IAAV G + GG L Sbjct: 81 SAGHDLRGGGEVPEKISLEFIIQHEARRYLDYTLRWRNVPKPSIAAVQGRCISGGLLLCW 140 Query: 148 MCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAG 207 CD+I A + A F P L+G G T +G A E++ TG ++A++A++ G Sbjct: 141 PCDLILASDDALFSDPVALMGI--GGVEYHGHTWELGPRKAKEILFTGRALTAEEAERTG 198 Query: 208 LVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEM 250 +V+++ + L + + AE+IA + AK +VN ++ Sbjct: 199 MVNRVVARDELDAQTRELAEQIATMPPFALRQAKRAVNQTLDV 241 >3HE2-A nrPDB Length = 264 Score = 206 bits (525), Expect = 7e-54, Method: Composition-based stats. Identities = 75/243 (30%), Positives = 116/243 (47%), Gaps = 10/243 (4%) Query: 47 VGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQNR 106 V I+L RP+ NAL + L+EEL QA+ D + AIVLTG AF AGAD+ Sbjct: 31 VLTIELQRPERRNALNSQLVEELTQAIRKA-GDGSARAIVLTGQGTAFCAGADLS---GD 86 Query: 107 TFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPEIL 166 F Y + + + PV+ A+NG A+G G +LAM CD+ A F P Sbjct: 87 AFAADYPDRLIELHKAMDASPMPVVGAINGPAIGAGLQLAMQCDLRVVAPDAFFQFPTSK 146 Query: 167 LGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAIQCA 226 G +RL+ VG A M+L+ ++++A+ A G+ ++I + +A A Sbjct: 147 YGLALDNWSIRRLSSLVGHGRARAMLLSAEKLTAEIALHTGMANRI----GTLADAQAWA 202 Query: 227 EKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGMSAFVEKRKAN 286 +IA + + + AK +N + + E K+LF + + D E A +EKR Sbjct: 203 AEIARLAPLAIQHAKRVLND--DGAIEEAWPAHKELFDKAWGSQDVIEAQVARMEKRPPK 260 Query: 287 FKD 289 F+ Sbjct: 261 FQG 263 >3HIN-A nrPDB Length = 275 Score = 206 bits (525), Expect = 8e-54, Method: Composition-based stats. Identities = 70/264 (26%), Positives = 116/264 (43%), Gaps = 4/264 (1%) Query: 28 ASGANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVL 87 A A T V I LNRPK NAL +GL+ L L + A+V+ Sbjct: 7 AQAATIADPSTLVVDTVGPVLTIGLNRPKKRNALNDGLMAALKDCLTDIP--DQIRAVVI 64 Query: 88 TGGEKAFAAGADIKEMQNRTFQDCY--SGKFLSHWDHITRIKKPVIAAVNGYALGGGCEL 145 G F+AG D+ E++ R + S + +D I + PVIAA+ G +GGG EL Sbjct: 65 HGIGDHFSAGLDLSELRERDATEGLVHSQTWHRVFDKIQYCRVPVIAALKGAVIGGGLEL 124 Query: 146 AMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQ 205 A I A A + PE G G GG+ RL R +G + +M+LTG SA + Sbjct: 125 ACAAHIRVAEASAYYALPEGSRGIFVGGGGSVRLPRLIGVARMADMMLTGRVYSAAEGVV 184 Query: 206 AGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYS 265 G + + ++A++ ++A N+ + +++ E G +E + Sbjct: 185 HGFSQYLIENGSAYDKALELGNRVAQNAPLTNFAVLQALPMIAEANPQTGLLMESLMATV 244 Query: 266 TFATDDRREGMSAFVEKRKANFKD 289 + + + + AF++ + A ++ Sbjct: 245 AQSDQEAKTRIRAFLDHKTAKVRE 268 >2A81-A nrPDB Length = 250 Score = 204 bits (519), Expect = 4e-53, Method: Composition-based stats. Identities = 60/237 (25%), Positives = 102/237 (43%), Gaps = 5/237 (2%) Query: 41 KGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGG-EKAFAAGAD 99 + + V +I L+ P N L + AL D +V A+V+ GG E++F+AG D Sbjct: 4 EENSDEVRVITLDHPNKHNPFSRTLETSVKDALARANADDSVRAVVVYGGAERSFSAGGD 63 Query: 100 IKEMQNRTFQDC---YSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGE 156 E++ + + + + + + + + KP IAAV+GYA+G G + A+M D Sbjct: 64 FNEVKQLSRSEDIEEWIDRVIDLYQAVLNVNKPTIAAVDGYAIGMGFQFALMFDQRLMAS 123 Query: 157 KAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVE 216 A F PE+ G + G L G S E++ + A LV+++ Sbjct: 124 TANFVMPELKHGI-GCSVGAAILGFTHGFSTMQEIIYQCQSLDAPRCVDYRLVNQVVESS 182 Query: 217 TLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRR 273 L++ AI A +A+ K +VN F L + K + + F D + Sbjct: 183 ALLDAAITQAHVMASYPASAFINTKRAVNKPFIHLLEQTRDASKAVHKAAFQARDAQ 239 >3I47-A nrPDB Length = 268 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 78/252 (30%), Positives = 120/252 (47%), Gaps = 7/252 (2%) Query: 44 NSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEM 103 VGL+ +NR NA N L+ E+ L++ D V IVL K F+AGAD+ M Sbjct: 11 QDKVGLLTMNRISKHNAFDNQLLTEMRIRLDSAINDTNVRVIVLKANGKHFSAGADLTWM 70 Query: 104 Q---NRTFQDCYSGKFL--SHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKA 158 Q N T ++ + + I++ KP IA V G A GGG LA CDI A A Sbjct: 71 QSMANFTEEENLEDSLVLGNLMYSISQSPKPTIAMVQGAAFGGGAGLAAACDIAIASTSA 130 Query: 159 QFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETL 218 +F E+ LG IP A + + RA+G+ A + ++ + A A LV P +TL Sbjct: 131 RFCFSEVKLGLIP-AVISPYVVRAIGERAAKMLFMSAEVFDATRAYSLNLVQHCVPDDTL 189 Query: 219 VEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGN-KLEKKLFYSTFATDDRREGMS 277 +E ++ A +I+NN+ V +K+ + E + L +D+ +EG+ Sbjct: 190 LEFTLKYASQISNNAPEAVKNSKQLAQYVANKKIDEELVRYTASLIAHKRVSDEGQEGLK 249 Query: 278 AFVEKRKANFKD 289 AF+ K N+ + Sbjct: 250 AFLNKEIPNWNE 261 >5KJP-A nrPDB Length = 265 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 82/245 (33%), Positives = 125/245 (51%), Gaps = 3/245 (1%) Query: 45 SSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQ 104 + +I +NRPKA NA+ + L A++ + D + +LTGG +F AG D+K Sbjct: 23 DRILIITINRPKAKNAVNAAVSRGLADAMDQLDGDAGLSVAILTGGGGSFCAGMDLKAFA 82 Query: 105 NRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPE 164 R G+ L + KP+IAAV GYAL GG ELA+ D+I A + FG PE Sbjct: 83 -RGENVVVEGRGLGFTERPPT--KPLIAAVEGYALAGGTELALAADLIVAARDSAFGIPE 139 Query: 165 ILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAIQ 224 + G + G GG RL + ++AME+ LTGD + A+ A + GLV+ + T ++ AI Sbjct: 140 VKRGLVAGGGGLLRLPERIPYAIAMELALTGDNLPAERAHELGLVNVLAEPGTALDAAIA 199 Query: 225 CAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGMSAFVEKRK 284 AEKI N + V K + + + + K+ F ++D +EG AF E+R+ Sbjct: 200 LAEKITANGPLAVVATKRIITESRGWSPDTMFAEQMKILVPVFTSNDAKEGAIAFAERRR 259 Query: 285 ANFKD 289 + Sbjct: 260 PRWTG 264 >4IZC-A nrPDB Length = 275 Score = 193 bits (490), Expect = 9e-50, Method: Composition-based stats. Identities = 69/250 (27%), Positives = 111/250 (44%), Gaps = 6/250 (2%) Query: 43 KNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKE 102 +++ V ++ LNRP NAL IEEL T V A+VLTG F AG D+ E Sbjct: 17 RDNGVCVVTLNRPDKRNALDVATIEELVTFFSTAHR-KGVRAVVLTGAGDHFCAGLDLVE 75 Query: 103 M--QNRTFQDCYSG--KFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKA 158 +R+ D ++ ++ + P+IAA+ G +GGG LA + + Sbjct: 76 HWKADRSADDFMHVCLRWHEAFNKMEYGGVPIIAALRGAVVGGGLALASAAHLRVMDQST 135 Query: 159 QFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETL 218 F PE G G G T R++ +GK ++M+LTG Q+A GL I + Sbjct: 136 YFALPEGQRGIFTGGGATIRVSDMIGKYRMIDMILTGRVYQGQEAADLGLAQYITEGSSF 195 Query: 219 VEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGMSA 278 ++A++ A+KIA+N + +++ M+ + E + RE + A Sbjct: 196 -DKAMELADKIASNLPLTNFAICSAISHMQNMSGLDAAYAEAFVGGIVNTQPAARERLEA 254 Query: 279 FVEKRKANFK 288 F K A + Sbjct: 255 FANKTAARVR 264 >1XX4-A nrPDB Length = 261 Score = 189 bits (479), Expect = 1e-48, Method: Composition-based stats. Identities = 56/254 (22%), Positives = 106/254 (41%), Gaps = 7/254 (2%) Query: 36 IITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGG-EKAF 94 ++ EK+G + + +++ P +N+L + E +LE E D ++ ++LT F Sbjct: 6 VLVEKEG-EAGIAVMKFKNP-PVNSLSLEFLTEFVISLEKLENDKSIRGVILTSERPGIF 63 Query: 95 AAGADIKEMQNRTFQ--DCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDII 152 +AG D+ EM R Y W + +I+A+NG + GGC +A+ CD Sbjct: 64 SAGLDLMEMYGRNPAHYAEYWKAVQELWLRLYLSNLTLISAINGASPAGGCLMALTCDYR 123 Query: 153 YAGEKAQ--FGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVS 210 + ++ G E LLG + +G A + G +A + GLV Sbjct: 124 IMADNSKYTIGLNESLLGIVAPFWLKDNYVNTIGHRAAERALQLGTLFPPAEALKVGLVD 183 Query: 211 KIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATD 270 ++ P + + +A K + K + A L + + + + F S + D Sbjct: 184 EVVPEDQVHSKARSVMAKWFTIPDHSRQLTKSMMRKATADNLIKQREADIQNFTSFISRD 243 Query: 271 DRREGMSAFVEKRK 284 ++ + ++EK K Sbjct: 244 SIQKSLHVYLEKLK 257 >3LAO-A nrPDB Length = 258 Score = 189 bits (479), Expect = 2e-48, Method: Composition-based stats. Identities = 64/244 (26%), Positives = 106/244 (43%), Gaps = 3/244 (1%) Query: 40 KKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGAD 99 + + + LI L+R NA + ++ +L A+ +E VL + F AG D Sbjct: 15 TREQRGHLFLIGLDRAGKRNAFDSAMLADLALAMGEYERSEESRCAVLFAHGEHFTAGLD 74 Query: 100 IKEMQNRTFQDC--YSGKFLSHWDHI-TRIKKPVIAAVNGYALGGGCELAMMCDIIYAGE 156 + E+ + Y + W + R KP++ AV G G EL + DI A Sbjct: 75 LMELAPKLAASGFRYPDGGVDPWGVVQPRRSKPLVVAVQGTCWTAGIELMLNADIAVAAR 134 Query: 157 KAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVE 216 +F E+L G P G T R RA G + AM +LTGD A +A + L++++ Sbjct: 135 GTRFAHLEVLRGIPPLGGSTVRFPRAAGWTDAMRYILTGDEFDADEALRMRLLTEVVEPG 194 Query: 217 TLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGM 276 + A++ AE+IA + + V A +S + + + ++D REG+ Sbjct: 195 EELARALEYAERIARAAPLAVRAALQSAFQGRDEGDDAALSRVNESLAALIGSEDVREGV 254 Query: 277 SAFV 280 A V Sbjct: 255 LAMV 258 >4ZU2-A nrPDB Length = 272 Score = 184 bits (467), Expect = 4e-47, Method: Composition-based stats. Identities = 72/250 (28%), Positives = 110/250 (44%), Gaps = 7/250 (2%) Query: 46 SVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQN 105 V I LNRP++ NA+ ++ EL L +D +V A+VL G + F AG DIK+M Sbjct: 16 GVLRITLNRPQSRNAMSLAMVGELRAVLAAVRDDRSVRALVLRGADGHFCAGGDIKDMAG 75 Query: 106 RTFQDCYSGK-----FLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQF 160 + + F S + + ++A V G LGGG LA + D+ A AQF Sbjct: 76 ARAAGAEAYRTLNRAFGSLLEEAQAAPQLLVALVEGAVLGGGFGLACVSDVAIAAADAQF 135 Query: 161 GQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKI-FPVETLV 219 G PE LG +P A + R +G + A + LT R ++A + GLV + L Sbjct: 136 GLPETSLGILP-AQIAPFVVRRIGLTQARRLALTAARFDGREALRLGLVHFCEADADALE 194 Query: 220 EEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGMSAF 279 + + E++ + A K + A+ L + F + EG AF Sbjct: 195 QRLEETLEQLRRCAPNANAATKALLLASESGELGALLDDAARQFAEAVGGAEGSEGTLAF 254 Query: 280 VEKRKANFKD 289 V+KRK + Sbjct: 255 VQKRKPVWAQ 264 >3BPT-A nrPDB Length = 363 Score = 180 bits (458), Expect = 5e-46, Method: Composition-based stats. Identities = 70/241 (29%), Positives = 109/241 (45%), Gaps = 10/241 (4%) Query: 42 GKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG-GEKAFAAGADI 100 GK G+I LNRPK LNAL +I ++ L+ +E+DP I++ G G KAF AG DI Sbjct: 11 GKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDI 70 Query: 101 KEM--QNRTFQDCYSGKFLSHW---DHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAG 155 + + + Q F + + + +KP +A ++G +GGG L++ A Sbjct: 71 RVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVAT 130 Query: 156 EKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPV 215 EK F PE +G P GG L R GK L + LTG R+ +D +AG+ + Sbjct: 131 EKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRDVYRAGIATHFVDS 189 Query: 216 ETL--VEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRR 273 E L +EE + A K + I + + + + + S F+ + Sbjct: 190 EKLAMLEEDL-LALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSCFSANTVE 248 Query: 274 E 274 E Sbjct: 249 E 249 Score = 42.3 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 27/71 (38%), Gaps = 2/71 (2%) Query: 220 EEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGMSAF 279 A++ + I S + + + TL E +E +L + D EG+ A Sbjct: 260 SFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAV 319 Query: 280 V--EKRKANFK 288 + + + +K Sbjct: 320 LIDKDQSPKWK 330 >2NP9-A nrPDB Length = 440 Score = 179 bits (453), Expect = 2e-45, Method: Composition-based stats. Identities = 71/284 (25%), Positives = 123/284 (43%), Gaps = 42/284 (14%) Query: 2 AALRALL--PRACNSLLSPVR-----CPEFRRFASGANFQYIITEKKGKNSSVGLIQLNR 54 A LR+ L P +++L P PEF R + + E++ V + + R Sbjct: 129 AVLRSPLAGPHLLDAMLRPTPRALELLPEFVRTGE-VEMEAVHLERR---DGVARLTMCR 184 Query: 55 PKALNALCNGLIEELNQALETFEEDPAVGAIVLTGG---------EKAFAAGADIKEMQ- 104 LNA ++++ A++ DP V +L GG ++ F+AG ++K + Sbjct: 185 DDRLNAEDGQQVDDMETAVDLALLDPGVRVGLLRGGVMSHPRYRGKRVFSAGINLKYLSQ 244 Query: 105 -----------------NRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAM 147 ++ + + W H RI+KP +AAV+G+A+GGG +L + Sbjct: 245 GGISLVDFLMRRELGYIHKLVRGVLTNDDRPGWWHSPRIEKPWVAAVDGFAIGGGAQLLL 304 Query: 148 MCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAG 207 + D + A A F P G IPGA RL R G ++ +++L G RI A++ + Sbjct: 305 VFDRVLASSDAYFSLPAAKEGIIPGAANL-RLGRFAGPRVSRQVILEGRRIWAKEPEARL 363 Query: 208 LVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMT 251 LV ++ + L + AI+ + V + +N A E Sbjct: 364 LVDEVVEPDEL-DAAIE--RSLTRLDGDAVLANRRMLNLADESP 404 >6IUM-B nrPDB Length = 701 Score = 175 bits (445), Expect = 1e-44, Method: Composition-based stats. Identities = 79/281 (28%), Positives = 124/281 (44%), Gaps = 36/281 (12%) Query: 37 ITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAA 96 +T + V +I L+ P +N L + + + + +D AV AIV+TG KAF+ Sbjct: 1 MTAQYQVQDGVAVITLDNP-PVNGLGHSTRLGIVEGMTRALDDAAVKAIVITGAGKAFSG 59 Query: 97 GADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGE 156 GADI+E T + S + KPV+AAV+ A+GGG ELA+ C+ A + Sbjct: 60 GADIREFN--TPKAMQEPTLHSVIRVLEGSSKPVVAAVHSVAMGGGLELALGCNYRVASK 117 Query: 157 KAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVE 216 AQ PE+ LG +PGAGGTQRL R +G A M+++G + ++ L +I + Sbjct: 118 GAQIALPEVKLGLLPGAGGTQRLPRVIGLEAAANMIVSGTPVLSEKFAGTKLFDEIVDGD 177 Query: 217 TLVEEAIQCAEKI--ANNSKIIVAMAK-----------------ESVNAAFEMTL----- 252 ++ A++ A+ + A V K ++ F L Sbjct: 178 -VLPAAVKFAQNVGAATGPHPKVRDLKVRHENPEGYLGFARNTVAAMAKNFPAPLKCLEA 236 Query: 253 --------TEGNKLEKKLFYSTFATDDRREGMSAFVEKRKA 285 +G K E++ F T + R AF +R A Sbjct: 237 VAGSLKPFEQGLKQEREGFLYLVTTPESRALRHAFFGERAA 277 >5ZRV-A nrPDB Length = 763 Score = 174 bits (441), Expect = 5e-44, Method: Composition-based stats. Identities = 71/228 (31%), Positives = 109/228 (47%), Gaps = 20/228 (8%) Query: 25 RRFASGANFQYIITEKKGKNSSVGLIQLNRPK-ALNALCNGLIEELNQALETFEEDPAVG 83 R F + G V ++++N P +N L L E ++ + + Sbjct: 27 RNFTGSSALLTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIR 86 Query: 84 -AIVLTGGEKAFAAGADIKEMQN-RTFQDC--YSGKFLSHWDHITRIKKPVIAAVNGYAL 139 A++++ F AGADI + +T Q+ S + + + + KP++AA+NG L Sbjct: 87 SAVLISSKPGCFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCL 146 Query: 140 GGGCELAMMCDIIYAG--EKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDR 197 GGG E+A+ C A K G PE+LLG +PGAGGTQRL + VG A++M+LTG Sbjct: 147 GGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRS 206 Query: 198 ISAQDAKQAGLVSKIFPV-------------ETLVEEAIQCAEKIANN 232 I A AK+ GLV ++ E L E AI A+ +A+ Sbjct: 207 IRADRAKKMGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADK 254 >4Q1J-A nrPDB Length = 268 Score = 173 bits (438), Expect = 9e-44, Method: Composition-based stats. Identities = 55/245 (22%), Positives = 111/245 (45%), Gaps = 1/245 (0%) Query: 33 FQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEK 92 + + E S++ +++ NA L ++L QA E ++P A++LTG + Sbjct: 20 MTHSVVELIEIESAIIQVKMQDRTHKNAFSQELTDDLIQAFEYIRQNPKYKAVILTGYDN 79 Query: 93 AFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDII 152 FA+G +E R Q + + + PVIAA+ G+ +GGG + + DI+ Sbjct: 80 YFASGG-TQEGLLRIQQGLTKFTDDNLYSLALDCEIPVIAAMQGHGIGGGFVMGLFADIV 138 Query: 153 YAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKI 212 ++ + + G PG G T + + +G SLA E++L D ++ G+ K+ Sbjct: 139 ILSRESVYTANFMKYGFTPGMGATFIVPKKLGFSLAQEILLNAGSYRGADLEKRGVPFKV 198 Query: 213 FPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDR 272 P +++ A++ A+++A + + K+ + A L + E + TF ++ Sbjct: 199 LPRAEVLDYAVELAQELAEKPRNSLVTLKDHLVAPLRDQLPRVIEQELMMAEKTFHHEEV 258 Query: 273 REGMS 277 + + Sbjct: 259 KSRIK 263 >3ZWA-A nrPDB Length = 742 Score = 169 bits (427), Expect = 2e-42, Method: Composition-based stats. Identities = 88/278 (31%), Positives = 129/278 (46%), Gaps = 41/278 (14%) Query: 46 SVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQN 105 S+ +I+L P +NA+ +I E+ L+ D V AIV+ G F AGADI Sbjct: 30 SLAMIRLCNP-PVNAVSPTVIREVRNGLQKAGSDHTVKAIVICGANGNFCAGADIHGFSA 88 Query: 106 RTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPEI 165 T S D I R +KPV+AA+ G ALGGG ELA+ C A KA+ G PE+ Sbjct: 89 FTP----GLALGSLVDEIQRYQKPVLAAIQGVALGGGLELALGCHYRIANAKARVGLPEV 144 Query: 166 LLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAIQC 225 LG +PGA GTQ L R VG +A++++ +G +SA +A + G++ + + + EEAI+ Sbjct: 145 TLGILPGARGTQLLPRVVGVPVALDLITSGKYLSADEALRLGILDAVVKSDPV-EEAIKF 203 Query: 226 AEKIANNS-------------------KIIVAMAK---------------ESVNAAFEMT 251 A+KI + A+AK S+ A+ + Sbjct: 204 AQKIIDKPIEPRRIFNKPVPSLPNMDSVFAEAIAKVRKQYPGVLAPETCVRSIQASVKHP 263 Query: 252 LTEGNKLEKKLFYSTFATDDRREGMSAFV-EKRKANFK 288 G K E+KLF A+ + AF EK + Sbjct: 264 YEVGIKEEEKLFMYLRASGQAKALQYAFFAEKSANKWS 301 >2WTB-A nrPDB Length = 725 Score = 168 bits (425), Expect = 3e-42, Method: Composition-based stats. Identities = 73/199 (36%), Positives = 101/199 (50%), Gaps = 6/199 (3%) Query: 45 SSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIK--- 101 V +I L P +N+L ++ L E V AIV+TG + F+ G DI Sbjct: 16 DGVAVITLINP-PVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFG 74 Query: 102 EMQNRTFQDCYSG--KFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQ 159 EMQ ++ +G D + +KP +AA++G ALGGG ELAM C + AQ Sbjct: 75 EMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQ 134 Query: 160 FGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLV 219 G PE+ LG IPG GGTQRL R VG + A+EM+LT + A++ GL+ + P LV Sbjct: 135 LGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELV 194 Query: 220 EEAIQCAEKIANNSKIIVA 238 A + A I K V+ Sbjct: 195 TTARRWALDIVGRRKPWVS 213 >4JSB-A nrPDB Length = 296 Score = 163 bits (412), Expect = 9e-41, Method: Composition-based stats. Identities = 62/244 (25%), Positives = 95/244 (38%), Gaps = 21/244 (8%) Query: 44 NSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEM 103 + V I L+RP NA+ + EL + T + AV +V+TG F++G D+ Sbjct: 43 DGEVARITLSRPHRRNAMTGRMWTELARIGHTLPQ--AVRIVVITGEGPTFSSGIDLDMF 100 Query: 104 QNRTFQ-------------------DCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCE 144 Q D + + + R IAAV G+A+G G + Sbjct: 101 QAGKVDGEPTPFTLLARDPNSTAALDQVIASYQEGFLWLRRADIVSIAAVRGHAIGAGFQ 160 Query: 145 LAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAK 204 LA+ CDI + AQ E LG +P GTQ L VG + A+E+ LT I A +A Sbjct: 161 LALSCDIRILSDTAQLCMKEPALGLVPDLTGTQPLVELVGVNRAIELCLTARTIDAAEAA 220 Query: 205 QAGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFY 264 Q L ++ L ++ KE + A L ++E+ Sbjct: 221 QLRLAERVVADAELDAAVDALVAQLLAVPAAAARATKELLLQAGRNDLATQARVERTAQL 280 Query: 265 STFA 268 + A Sbjct: 281 ARLA 284 >4J2U-A nrPDB Length = 365 Score = 162 bits (411), Expect = 1e-40, Method: Composition-based stats. Identities = 70/258 (27%), Positives = 103/258 (39%), Gaps = 10/258 (3%) Query: 29 SGANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLT 88 FQ + K G I L+RP ALNAL +++E++ AL + DP V +V+ Sbjct: 16 ENLYFQSMSDVLIRKVRRAGRITLSRPAALNALTCAMVQEIDAALRGWIGDPEVELVVID 75 Query: 89 G-GEKAFAAGADIKEMQNRTF-------QDCYSGKFLSHWDHITRIKKPVIAAVNGYALG 140 G +AF AG DI E+ R QD + ++ + D I KP+++ + G+ +G Sbjct: 76 AEGPRAFCAGGDIAELHGRGVAGDHAFGQDFWRVEYRMN-DRIAAFPKPIVSLMQGFTMG 134 Query: 141 GGCELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISA 200 GG L GE +Q PE +G +P GGT L RA G + + + LTG R+ Sbjct: 135 GGVGLGCHARHRIVGETSQISMPECAIGLVPDVGGTHLLARAPG-RIGVWLGLTGARMGP 193 Query: 201 QDAKQAGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEK 260 DA AG + P + + V L G E Sbjct: 194 GDAIFAGFADRFVPEADWPDLIAALEGGDLALPDHAAPEGRLPVLQDEIDRLFAGTLAEI 253 Query: 261 KLFYSTFATDDRREGMSA 278 T E + A Sbjct: 254 PARLEATDTPLAAEALKA 271 >5MRE-88 nrPDB Length = 457 Score = 162 bits (411), Expect = 1e-40, Method: Composition-based stats. Identities = 50/198 (25%), Positives = 83/198 (41%), Gaps = 13/198 (6%) Query: 43 KNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGG--EKAFAAGADI 100 + +I LNRPK LNAL + E + + L + + ++L ++F AG D+ Sbjct: 8 VQDTARVITLNRPKKLNALNAEMSESMFKTLNEYAKSDTTNLVILKSSNRPRSFCAGGDV 67 Query: 101 KEMQNRTFQDCYSGKFLSHWD------HITRIKKPVIAAVNGYALGGGCELAMMCDIIYA 154 + F ++ D I KP++ ++G +GGG L++ A Sbjct: 68 ATVAIFNFNKEFAKSIKFFTDEYSLNFQIATYLKPIVTFMDGITMGGGVGLSIHTPFRIA 127 Query: 155 GEKAQFGQPEILLGTIPGAGGTQRLTRAV-----GKSLAMEMVLTGDRISAQDAKQAGLV 209 E ++ PE+ +G P G T L R V +A+ + LTG+ ++ DA GL Sbjct: 128 TENTKWAMPEMDIGFFPDVGSTFALPRIVTLANSNSQMALYLCLTGEVVTGADAYMLGLA 187 Query: 210 SKIFPVETLVEEAIQCAE 227 S E L + E Sbjct: 188 SHYVSSENLDALQKRLGE 205 >2D3T-A nrPDB Length = 715 Score = 159 bits (403), Expect = 1e-39, Method: Composition-based stats. Identities = 61/242 (25%), Positives = 103/242 (42%), Gaps = 27/242 (11%) Query: 44 NSSVGLIQLN-RPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKE 102 S + ++ + + +++N + EL QA++ + D +V ++++ G+ F GADI E Sbjct: 14 ESGIVELKFDLKGESVNKFNRLTLNELRQAVDAIKADASVKGVIVSSGKDVFIVGADITE 73 Query: 103 MQN--RTFQDCYSGKFLS---HWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEK 157 + L + + P +AA+NG ALGGG E+ + D + Sbjct: 74 FVENFKLPDAELIAGNLEANKIFSDFEDLNVPTVAAINGIALGGGLEMCLAADFRVMADS 133 Query: 158 AQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVET 217 A+ G PE+ LG PG GGT RL R +G A+E + +G A+DA + V + + Sbjct: 134 AKIGLPEVKLGIYPGFGGTVRLPRLIGVDNAVEWIASGKENRAEDALKVSAVDAVVTADK 193 Query: 218 LVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGMS 277 L A+ K +++ + KLEK + E M Sbjct: 194 LGAAALDL--------------IKRAISGELDYKAKRQPKLEKLKLNAI-------EQMM 232 Query: 278 AF 279 AF Sbjct: 233 AF 234 >4HDT-A nrPDB Length = 353 Score = 152 bits (384), Expect = 2e-37, Method: Composition-based stats. Identities = 73/311 (23%), Positives = 126/311 (40%), Gaps = 65/311 (20%) Query: 42 GKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGE-KAFAAGADI 100 VGL+ LNRPKA+N+L +G++ + + L +E D +V A++LTG + AG D+ Sbjct: 14 NVEGGVGLLTLNRPKAINSLTHGMVTTMAERLAAWENDDSVRAVLLTGAGERGLCAGGDV 73 Query: 101 KEMQNRTFQDCYSGKFLSHWD-----HITRIKKPVIAAVNGYALGGGCELAMMCDIIYAG 155 + + D + + HI R KP ++ ++G +GGG + ++ Sbjct: 74 VAIYHSAKADGAEARRFWFDEYRLNAHIGRYPKPYVSIMDGIVMGGGVGVGAHGNVRVVT 133 Query: 156 EKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPV 215 + + PE+ +G IP GGT L+RA GK L + LTG S DA G P Sbjct: 134 DTTKMAMPEVGIGFIPDVGGTYLLSRAPGK-LGLHAALTGAPFSGADAIVMGFADHYVPH 192 Query: 216 ETLVEEAIQ---------------------CAEK-------------------------- 228 + + E AE+ Sbjct: 193 DKIDEFTRAVIADGVDAALAAHAQEPPASPLAEQRSWIDECYTGDTVADIIAALRAHDAP 252 Query: 229 --------IANNSKIIVAMAKESVNAAFEM-TLTEGNKLEKKLFYSTFATDDRREGMSAF 279 IA S I +++ ESV A ++ +L + + E ++ ++ + D EG+ A Sbjct: 253 AAGEAADLIATRSPIALSVTLESVRRAAKLQSLEDTLRQEYRVSCASLKSHDLVEGIRAQ 312 Query: 280 V--EKRKANFK 288 + + R ++ Sbjct: 313 LVDKDRNPKWR 323 >3HP0-A nrPDB Length = 267 Score = 151 bits (382), Expect = 3e-37, Method: Composition-based stats. Identities = 56/194 (28%), Positives = 76/194 (39%), Gaps = 9/194 (4%) Query: 29 SGANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLT 88 S +Q I K +SV I +RP+A N + + LIEE Q L E V +VL Sbjct: 2 SLVTYQTI---KVRFQASVCYITFHRPEANNTINDTLIEECLQVLNQCETS-TVTVVVLE 57 Query: 89 GGEKAFAAGADIKEMQN----RTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCE 144 G + F GAD +E+ Q W + I+ V G GG Sbjct: 58 GLPEVFCFGADFQEIYQEMKRGRKQASSQEPLYDLWMKLQTGPYVTISHVRGKVNAGGLG 117 Query: 145 LAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAK 204 DI A + A F E+L G P A L R +G+ A M L IS Q+A Sbjct: 118 FVSATDIAIADQTASFSLSELLFGLYP-ACVLPFLIRRIGRQKAHYMTLMTKPISVQEAS 176 Query: 205 QAGLVSKIFPVETL 218 + GL+ + Sbjct: 177 EWGLIDAFDAESDV 190 >3JU1-A nrPDB Length = 407 Score = 138 bits (349), Expect = 2e-33, Method: Composition-based stats. Identities = 51/181 (28%), Positives = 83/181 (45%), Gaps = 11/181 (6%) Query: 47 VGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG-GEKAFAAGADIKEMQN 105 VG++ LN KALNAL ++ + L +++DP + +VL G GEKAF AG D++ + + Sbjct: 52 VGVVTLNVEKALNALDLDMVRAMTVQLNLWKKDPLIACVVLDGSGEKAFCAGGDVRALYH 111 Query: 106 RTFQ------DCYSGKFLSHWDH---ITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGE 156 + + F + + KPV+ +G +GGG L E Sbjct: 112 ASVAAKGQVTEVAKVFFEEEYRLDYLLHTYGKPVLVWGDGIVMGGGLGLMAGASHKVVTE 171 Query: 157 KAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVE 216 ++ PE+ +G P GG+ L R GK + + + LT ++A DA GL + Sbjct: 172 TSRIAMPEVTIGLYPDVGGSYFLNRMPGK-MGLFLGLTAYHMNAADACYVGLADHYLNRD 230 Query: 217 T 217 Sbjct: 231 D 231 >4HC8-A nrPDB Length = 255 Score = 135 bits (339), Expect = 2e-32, Method: Composition-based stats. Identities = 48/226 (21%), Positives = 86/226 (38%), Gaps = 4/226 (1%) Query: 43 KNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKE 102 + S+ +I ++ K +NAL + + LN A++ + D VGA+V+TG + F+ G D+K Sbjct: 11 RKDSIAVISMDDGK-VNALGPAMQQALNAAIDNADRDD-VGALVITGNGRVFSGGFDLKI 68 Query: 103 MQNRTFQDC--YSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQF 160 + + Q + KPV+ A G+A+ G L D A Sbjct: 69 LTSGEVQPAIDMLRGGFELAYRLLSYPKPVVMACTGHAIAMGAFLLSCGDHRVAAHAYNI 128 Query: 161 GQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVE 220 E+ +G + + + +S + + A AG + +I E +V Sbjct: 129 QANEVAIGMTIPYAALEIMKLRLTRSAYQQATGLAKTFFGETALAAGFIDEIALPEVVVS 188 Query: 221 EAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYST 266 A + A + A ++ A K A + G F Sbjct: 189 RAEEAAREFAGLNQHAHAATKLRSRADALTAIRAGIDGIAAEFGLA 234 >4ZDC-A nrPDB Length = 300 Score = 135 bits (339), Expect = 3e-32, Method: Composition-based stats. Identities = 52/238 (21%), Positives = 88/238 (36%), Gaps = 28/238 (11%) Query: 49 LIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQNRTF 108 +I L P LNAL L + LE + + V ++ + F++GAD K + Sbjct: 41 IIHLINPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGADFKGIAKAQG 100 Query: 109 QDC-------------YSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYA- 154 D + + + D + K +I +NG A+G L +CDI+Y+ Sbjct: 101 DDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVYSI 160 Query: 155 GEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFP 214 +K P LG I G T L G + E ++ + G +SK F Sbjct: 161 NDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISKNFN 220 Query: 215 VETLVEEAI--QCAEKIANNS-----KIIVAMAK-------ESVNAAFEMTLTEGNKL 258 + + EA + E++ + M K ++ N A + + E K Sbjct: 221 MPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFNKANSVEVNESLKY 278 >4B3J-A nrPDB Length = 736 Score = 128 bits (321), Expect = 3e-30, Method: Composition-based stats. Identities = 62/211 (29%), Positives = 93/211 (44%), Gaps = 10/211 (4%) Query: 34 QYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETF-EEDPAVGAIVLTGGEK 92 I K + V L + + N + IE + +A++ E ++ +V+ +K Sbjct: 19 DNTIQWDKDADGIVTLTMDDPSGSTNVMNEAYIESMGKAVDRLVAEKDSITGVVVASAKK 78 Query: 93 AFAAGADIKEMQNRTFQDC-----YSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAM 147 F AG D+K M +D + + KPV+AA+NG ALGGG E+A+ Sbjct: 79 TFFAGGDVKTMIQARPEDAGDVFNTVETIKRQLRTLETLGKPVVAAINGAALGGGLEIAL 138 Query: 148 MCDIIYAGE--KAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVL-TGDRISAQDAK 204 C A + +Q G PE+ LG +PG GG R R G A VL G R AK Sbjct: 139 ACHHRIAADVKGSQLGLPEVTLGLLPGGGGVTRTVRMFGIQNAFVSVLAQGTRFKPAKAK 198 Query: 205 QAGLVSKIFP-VETLVEEAIQCAEKIANNSK 234 + GLV ++ VE LV A ++ + Sbjct: 199 EIGLVDELVATVEELVPAAKAWIKEELKANP 229 >3M6N-A nrPDB Length = 305 Score = 110 bits (276), Expect = 6e-25, Method: Composition-based stats. Identities = 53/253 (20%), Positives = 89/253 (35%), Gaps = 25/253 (9%) Query: 24 FRRFASGANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVG 83 F R G+ + I + V I ++ A+N L + ++ + Sbjct: 23 FIRTNIGSTLRII----EEPQRDVYWIHMHADLAINPGRACFSTRLVDDITGYQTNLGQR 78 Query: 84 A---------IVLTGGEKAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRI-------- 126 +VL F G D+ ++ + L + R Sbjct: 79 LNTAGVLAPHVVLASDSDVFNLGGDLALFCQL-IREGDRARLLDYAQRCVRGVHAFHVGL 137 Query: 127 --KKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVG 184 + IA V G ALGGG E A+ C I A E G PE+L PG G + + + Sbjct: 138 GARAHSIALVQGNALGGGFEAALSCHTIIAEEGVMMGLPEVLFDLFPGMGAYSFMCQRIS 197 Query: 185 KSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESV 244 LA +++L G+ SA+ GLV ++ P V Q + + + A ++ Sbjct: 198 AHLAQKIMLEGNLYSAEQLLGMGLVDRVVPRGQGVAAVEQVIRE-SKRTPHAWAAMQQVR 256 Query: 245 NAAFEMTLTEGNK 257 + L E + Sbjct: 257 EMTTAVPLEEMMR 269 >3BF0-A nrPDB Length = 593 Score = 40.4 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 37/203 (18%), Positives = 57/203 (28%), Gaps = 59/203 (29%) Query: 70 NQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKP 129 + DP V AIVL + + S + KP Sbjct: 328 AAQIRDARLDPKVKAIVLR--------------VNSPGGSVTASEVIRAELAAARAAGKP 373 Query: 130 VIAAVNGYALGGGCELAMMCDIIYAGEKA------QFGQPEI------LLGTIPGAGGTQ 177 V+ ++ G A GG ++ + I A FG +G T Sbjct: 374 VVVSMGGMAASGGYWISTPANYIVANPSTLTGSIGIFGVITTVENSLDSIGVHTDGVSTS 433 Query: 178 RLT-----RAVGKSLAMEMVLT----------------------------GDRISAQDAK 204 L RA+ + M L+ G + QDAK Sbjct: 434 PLADVSITRALPPEAQLMMQLSIENGYKRFITLVADARHSTPEQIDKIAQGHVWTGQDAK 493 Query: 205 QAGLVSKIFPVETLVEEAIQCAE 227 GLV + + V +A + A+ Sbjct: 494 ANGLVDSLGDFDDAVAKAAELAK 516 >3SN5-A nrPDB Length = 491 Score = 32.3 bits (72), Expect = 0.26, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 35/88 (39%), Gaps = 6/88 (6%) Query: 55 PKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFA------AGADIKEMQNRTF 108 ALN+L ++E L + + + A +T G +F AG ++ T Sbjct: 118 GHALNSLTESMMENLQRIMRPPVSSNSKTAAWVTEGMYSFCYRVMFEAGYLTIFGRDLTR 177 Query: 109 QDCYSGKFLSHWDHITRIKKPVIAAVNG 136 +D L++ D+ + K A V G Sbjct: 178 RDTQKAHILNNLDNFKQFDKVFPALVAG 205 >1QDB-A nrPDB Length = 473 Score = 31.5 bits (70), Expect = 0.44, Method: Composition-based stats. Identities = 19/126 (15%), Positives = 43/126 (34%), Gaps = 17/126 (13%) Query: 149 CDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGL 208 D+ A F PE L + A G A + + + + G+ Sbjct: 358 ADMAIAAHGNYFHAPEETLRLL-----------AAGSDDAQK----ARLLLVKILAKHGV 402 Query: 209 VSKIFPVETLVEEAIQCAE-KIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTF 267 + I P ++A + A+ IA + + K+++ ++ + +L+ Sbjct: 403 MDYIAPDFDTKDKAQKLAKVDIAALAAEKMKF-KQTLEQEWKKEAKAKGRANPELYKDVD 461 Query: 268 ATDDRR 273 +D + Sbjct: 462 TINDGK 467 >3U9S-B nrPDB Length = 555 Score = 31.1 bits (69), Expect = 0.61, Method: Composition-based stats. Identities = 24/145 (16%), Positives = 45/145 (31%), Gaps = 31/145 (21%) Query: 95 AAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYA 154 + GA++ + G+ + +++ P IA V G GG + M D Sbjct: 165 SGGANLPRQDEVFPDREHFGRIFFNQANMSARGIPQIAVVMGSCTAGGAYVPAMSDETVM 224 Query: 155 GEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQD-------AKQAG 207 + Q G L TG+ +SA++ K +G Sbjct: 225 VRE-------------------QATIFLAGPPLVKAA--TGEVVSAEELGGADVHCKVSG 263 Query: 208 LVSKIFPVETLVEEAIQCAEKIANN 232 + + + A+ A + N Sbjct: 264 VADHYAEDD---DHALAIARRCVAN 285 >4KWB-A nrPDB Length = 273 Score = 30.7 bits (68), Expect = 0.68, Method: Composition-based stats. Identities = 25/121 (20%), Positives = 44/121 (36%), Gaps = 21/121 (17%) Query: 66 IEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQ--NRTFQDCYSGKFLSHWDHI 123 + LE ++D V IVL K + G + E ++ ++ Sbjct: 36 HRTFLKNLERAKDDKTVKGIVL----KVNSPGGGVYESAEIHKKLEEIKK---------- 81 Query: 124 TRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAV 183 KKP+ ++ A GG ++ D I+A + G LG I + +L + Sbjct: 82 -ETKKPIYVSMGSMAASGGYYISTAADKIFATPETLTG----SLGVIMESVNYSKLADKL 136 Query: 184 G 184 G Sbjct: 137 G 137 >3RST-A nrPDB Length = 240 Score = 30.7 bits (68), Expect = 0.68, Method: Composition-based stats. Identities = 25/121 (20%), Positives = 44/121 (36%), Gaps = 21/121 (17%) Query: 66 IEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQ--NRTFQDCYSGKFLSHWDHI 123 + LE ++D V IVL K + G + E ++ ++ Sbjct: 31 HRTFLKNLERAKDDKTVKGIVL----KVNSPGGGVYESAEIHKKLEEIKK---------- 76 Query: 124 TRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAV 183 KKP+ ++ A GG ++ D I+A + G LG I + +L + Sbjct: 77 -ETKKPIYVSMGSMAASGGYYISTAADKIFATPETLTG----SLGVIMESVNYSKLADKL 131 Query: 184 G 184 G Sbjct: 132 G 132 >1ON3-A nrPDB Length = 523 Score = 29.6 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 31/153 (20%), Positives = 51/153 (33%), Gaps = 27/153 (17%) Query: 86 VLTGGEKAF---AAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKK-PVIAAVNGYALGG 141 +LTG F + GA I+E D SG + ++ P IA + G GG Sbjct: 127 LLTGTPFLFFYDSGGARIQE-----GIDSLSGYGKMFFANVKLSGVVPQIAIIAGPCAGG 181 Query: 142 GCELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQ 201 + D I +KA I G + + ++ T D + Sbjct: 182 ASYSPALTDFIIMTKKAHM--------FITG-------PQVIKSVTGEDV--TADELGGA 224 Query: 202 DAKQAGLVSKIFPVETLVEEAIQCAEKIANNSK 234 +A + I V + A A+K+ + Sbjct: 225 EAH-MAISGNIHFVAEDDDAAELIAKKLLSFLP 256 >2C8T-A nrPDB Length = 206 Score = 29.2 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 7/27 (25%), Positives = 11/27 (40%) Query: 196 DRISAQDAKQAGLVSKIFPVETLVEEA 222 +A +A + G V I + EA Sbjct: 174 RWFTAAEALEYGFVDHIITRAHVNGEA 200 >1CHK-A nrPDB Length = 238 Score = 29.2 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 21/76 (27%), Positives = 30/76 (39%), Gaps = 9/76 (11%) Query: 88 TGGEKAFAAG-ADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELA 146 TGG F +G D+ E+ + D G L+ + + +KK VNG A G Sbjct: 45 TGGIIGFCSGTGDMLELVQH-YTDLEPGNILAKY--LPALKK-----VNGSASHSGLGTP 96 Query: 147 MMCDIIYAGEKAQFGQ 162 D A + F Q Sbjct: 97 FTKDWATAAKDTVFQQ 112 >6B5B-F nrPDB Length = 566 Score = 28.8 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 20/113 (17%), Positives = 29/113 (25%), Gaps = 34/113 (30%) Query: 45 SSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAV----------------GAIVLT 88 + V + LN +L A+ V I +T Sbjct: 352 NGVAIYT-----NLNVATALTNSDLRDAINGVSNQTGVVASLNGGNMTLTAADGRNITVT 406 Query: 89 GGEKAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGG 141 F AG D + F G I+AV+ A+GG Sbjct: 407 ESGTGFTAGTDGLTVTGGAFDGALRGTL-------------SISAVDTIAIGG 446 >4H27-A nrPDB Length = 364 Score = 28.8 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 26/57 (45%), Gaps = 2/57 (3%) Query: 181 RAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAIQCAEKIANNSKIIV 237 R +G + + T ++ + K G K+ L++EA + A+ +A N+ V Sbjct: 113 RQLGVPATIVVPGTTPALTIERLKNEGATVKVV--GELLDEAFELAKALAKNNPGWV 167 >1PWH-A nrPDB Length = 327 Score = 28.8 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 27/63 (42%), Gaps = 2/63 (3%) Query: 175 GTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAIQCAEKIANNSK 234 T R +G + + T ++ + K G ++ +++EAIQ A+ + N+ Sbjct: 71 ATAYAARRLGLPATIVVPSTTPALTIERLKNEGATVEVV--GEMLDEAIQLAKALEKNNP 128 Query: 235 IIV 237 V Sbjct: 129 GWV 131 >2NVK-X nrPDB Length = 488 Score = 28.4 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 26/94 (27%), Positives = 36/94 (38%), Gaps = 10/94 (10%) Query: 132 AAVNG------YALGGG-CELAMMCDIIYAGEKAQ---FGQPEILLGTIPGAGGTQRLTR 181 A V G +GGG LA + + G + F +P LGT G GGT Sbjct: 2 APVQGSYDYDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGTCVNVG 61 Query: 182 AVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPV 215 + K L + L G+ + A + KI P Sbjct: 62 CIPKKLMHQASLLGEAVHEAAAYGWNVDDKIKPD 95 >2YJN-B nrPDB Length = 381 Score = 28.0 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 28/166 (16%), Positives = 47/166 (28%), Gaps = 16/166 (9%) Query: 102 EMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVN----GYALGGGCELAMMCDII----Y 153 ++ F + P + + G G G L ++ D Sbjct: 109 MRAAGAPPAEWAQPFRDVHAASWEGEVPDVGELAESFAGLLPGAGARLDLVGDFAWQVPV 168 Query: 154 AGEKAQFGQPEILLGTIPGAGGT---QRLTRAVGKSLAMEMVLTGDRISAQDAKQAGL-- 208 G A G +L G A + Q + + + A L D A A AG Sbjct: 169 QGMTAVLGAAGVLRGAAWDARVSLDAQLSPQQLAVTEAAVAALPADP--ALRALFAGAEM 226 Query: 209 -VSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLT 253 + + V AE+IA++ E + + L Sbjct: 227 TANTVVDAVLAVSAEPGLAERIADDPAAAQRTVAEVLRLHPALHLE 272 >4Q28-A nrPDB Length = 113 Score = 28.0 bits (61), Expect = 4.8, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 27/67 (40%), Gaps = 2/67 (2%) Query: 194 TGDRISAQDAKQAGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLT 253 TG +S ++A +AGL+ V L + E+I+ + + + ++ Sbjct: 22 TGRELSPEEAHRAGLIDWNMFV-KLRSQECDW-EEISVKGPNGESSVIHDRKSGKKFSIE 79 Query: 254 EGNKLEK 260 E + + Sbjct: 80 EALQSGR 86 >3QWD-A nrPDB Length = 203 Score = 28.0 bits (61), Expect = 4.9, Method: Composition-based stats. Identities = 23/125 (18%), Positives = 41/125 (32%), Gaps = 29/125 (23%) Query: 117 LSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGT 176 + +D I IK V G A G L + +F P + GG Sbjct: 75 FAIYDTIQHIKPDVQTICIGMAASMGSFLLAAG-----AKGKRFALPNAEVMIHQPLGGA 129 Query: 177 Q------------------RLTRAVGKSLAMEM------VLTGDRISAQDAKQAGLVSKI 212 Q +L R + + + + ++A++AK+ GL+ ++ Sbjct: 130 QGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEV 189 Query: 213 FPVET 217 ET Sbjct: 190 MVPET 194 >1SKF-A nrPDB Length = 262 Score = 28.0 bits (61), Expect = 5.1, Method: Composition-based stats. Identities = 11/30 (36%), Positives = 14/30 (46%), Gaps = 3/30 (10%) Query: 126 IKKPVIAAVNGYALGGGCELAM---MCDII 152 + KP IAAV GYA+ G + D Sbjct: 1 VTKPTIAAVGGYAMNNGTGTTLYTKAADTR 30 >6MZL-P nrPDB Length = 211 Score = 27.7 bits (60), Expect = 5.5, Method: Composition-based stats. Identities = 15/54 (27%), Positives = 24/54 (44%), Gaps = 1/54 (1%) Query: 193 LTGDRISAQDAKQAGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNA 246 +TG +S +SK+F V +VEEA+ EK + +E+V Sbjct: 141 ITGTSVSQNVVIAMSGISKVF-VGEVVEEALDVCEKWGEMPPLQPKHMREAVRR 193 >3BEO-A nrPDB Length = 375 Score = 27.7 bits (60), Expect = 5.8, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 18/39 (46%) Query: 98 ADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNG 136 D+ M++R + + L D + + KP I V+G Sbjct: 65 FDLNIMKDRQTLIDITTRGLEGLDKVMKEAKPDIVLVHG 103 >1BH8-B nrPDB Length = 89 Score = 27.7 bits (60), Expect = 5.8, Method: Composition-based stats. Identities = 15/54 (27%), Positives = 24/54 (44%), Gaps = 1/54 (1%) Query: 193 LTGDRISAQDAKQAGLVSKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNA 246 +TG +S +SK+F V +VEEA+ EK + +E+V Sbjct: 29 ITGTSVSQNVVIAMSGISKVF-VGEVVEEALDVCEKWGEMPPLQPKHMREAVRR 81 >2OVL-A nrPDB Length = 371 Score = 27.7 bits (60), Expect = 5.9, Method: Composition-based stats. Identities = 30/142 (21%), Positives = 48/142 (33%), Gaps = 26/142 (18%) Query: 56 KALNALCNGLIEE---LNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQNRTFQDCY 112 ++AL L + + A + D A+ A +A A D+ ++ T D Sbjct: 179 DRVSALREHLGDSFPLMVDANMKWTVDGAIRAA------RAL-APFDLHWIEEPTIPDDL 231 Query: 113 SGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPEILLGTIPG 172 G I +G+ + GG L + D A PE + I G Sbjct: 232 VGNAR-------------IVRESGHTIAGGENLHTLYDFHNAVRAGSLTLPEPDVSNI-G 277 Query: 173 AGGTQRLTRAVGKSLAMEMVLT 194 T R + + A M+LT Sbjct: 278 GYTTFR--KVAALAEANNMLLT 297 >2YV2-A nrPDB Length = 297 Score = 27.7 bits (60), Expect = 6.0, Method: Composition-based stats. Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 18/69 (26%) Query: 68 ELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIK 127 +AL+ F+EDP A+VL G G D M+ R + G+F Sbjct: 193 SFTEALKLFQEDPQTEALVLIGE-----IGGD---MEERAAEMIKKGEF----------T 234 Query: 128 KPVIAAVNG 136 KPVIA + G Sbjct: 235 KPVIAYIAG 243 >2WWR-A nrPDB Length = 330 Score = 27.7 bits (60), Expect = 6.2, Method: Composition-based stats. Identities = 9/63 (14%), Positives = 23/63 (36%), Gaps = 2/63 (3%) Query: 160 FGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLV 219 +G + +G I Q + R + + TG + ++A + ++ L Sbjct: 151 YGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAE--FQAEFVSTPELA 208 Query: 220 EEA 222 ++ Sbjct: 209 AQS 211 >4WHX-A nrPDB Length = 311 Score = 27.7 bits (60), Expect = 6.5, Method: Composition-based stats. Identities = 8/45 (17%), Positives = 19/45 (42%) Query: 179 LTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAI 223 L + G + + + + +A +A G +++ P+ L I Sbjct: 233 LAKEAGIEVIEKRITRDEVYTADEAFFTGTAAEVTPIRELDNRTI 277 >2GQD-A nrPDB Length = 437 Score = 27.7 bits (60), Expect = 7.0, Method: Composition-based stats. Identities = 29/138 (21%), Positives = 46/138 (33%), Gaps = 2/138 (1%) Query: 85 IVLTGGEKAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCE 144 IV G A G + + + + LS D I +P +G+ +G G Sbjct: 201 IVQRGDADAMITGGTEAPITHMAIAGFSASRALSTNDDIETACRPFQEGRDGFVMGEGAG 260 Query: 145 LAMMCDIIYA-GEKAQFGQPEILLGTIPGAG-GTQRLTRAVGKSLAMEMVLTGDRISAQD 202 + ++ + A A + GT A T G S AM+ + I +D Sbjct: 261 ILVIESLESAQARGANIYAEIVGYGTTGDAYHITAPAPEGEGGSRAMQAAMDDAGIEPKD 320 Query: 203 AKQAGLVSKIFPVETLVE 220 + PV L E Sbjct: 321 VQYLNAHGTSTPVGDLNE 338 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.139 0.368 Lambda K H 0.267 0.0422 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,608,758 Number of Sequences: 36641 Number of extensions: 407963 Number of successful extensions: 1706 Number of sequences better than 10.0: 95 Number of HSP's better than 10.0 without gapping: 116 Number of HSP's successfully gapped in prelim test: 42 Number of HSP's that attempted gapping in prelim test: 1402 Number of HSP's gapped (non-prelim): 163 length of query: 290 length of database: 10,336,785 effective HSP length: 96 effective length of query: 194 effective length of database: 6,819,249 effective search space: 1322934306 effective search space used: 1322934306 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.3 bits)