BLASTP 2.2.23 [Feb-03-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= P14384
         (443 letters)

Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 
           36,641 sequences; 10,336,785 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

1UWY-A nrPDB                                                          888   0.0  
1QMU-A nrPDB                                                          365   e-101
3MN8-A nrPDB                                                          323   6e-89
2NSM-A nrPDB                                                          301   5e-82
3V7Z-A nrPDB                                                           72   5e-13
4A39-A nrPDB                                                           54   2e-07
1KWM-A nrPDB                                                           49   4e-06
1ZLI-A nrPDB                                                           49   5e-06
4BD9-A nrPDB                                                           46   4e-05
2BOA-A nrPDB                                                           45   5e-05
3OSL-A nrPDB                                                           45   7e-05
4B6Z-A nrPDB                                                           45   8e-05
3D4U-A nrPDB                                                           44   1e-04
1DTD-A nrPDB                                                           44   1e-04
1JQG-A nrPDB                                                           44   2e-04
3K2K-A nrPDB                                                           44   2e-04
1AYE-A nrPDB                                                           43   2e-04
5AQ0-A nrPDB                                                           41   0.001
4UIB-A nrPDB                                                           40   0.002
3GLJ-A nrPDB                                                           39   0.005
1NSA-A nrPDB                                                           39   0.006
3KGQ-A nrPDB                                                           36   0.027
3L2N-A nrPDB                                                           36   0.032
3D68-A nrPDB                                                           35   0.068
3LMS-A nrPDB                                                           35   0.072
4UEE-A nrPDB                                                           33   0.18 
2QVP-A nrPDB                                                           33   0.21 
5MRV-A nrPDB                                                           33   0.21 
5OM9-A nrPDB                                                           33   0.29 
1PCA-A nrPDB                                                           32   0.53 
5HXD-A nrPDB                                                           32   0.60 
4GFJ-A nrPDB                                                           31   0.86 
5HM5-A nrPDB                                                           31   0.97 
3IEH-A nrPDB                                                           31   1.0  
2C1C-A nrPDB                                                           30   2.2  
6D97-A nrPDB                                                           30   2.6  
3B2Y-A nrPDB                                                           29   3.2  
3N5M-A nrPDB                                                           28   6.5  
1SEZ-A nrPDB                                                           28   8.8  
1YKN-B nrPDB                                                           28   9.4  

>1UWY-A nrPDB
          Length = 426

 Score =  888 bits (2295), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 426/426 (100%), Positives = 426/426 (100%)

Query: 18  LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77
           LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK
Sbjct: 1   LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 60

Query: 78  YVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPD 137
           YVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPD
Sbjct: 61  YVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPD 120

Query: 138 CYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVAS 197
           CYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVAS
Sbjct: 121 CYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVAS 180

Query: 198 YPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYS 257
           YPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYS
Sbjct: 181 YPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYS 240

Query: 258 WYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKG 317
           WYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKG
Sbjct: 241 WYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKG 300

Query: 318 QVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVI 377
           QVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVI
Sbjct: 301 QVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVI 360

Query: 378 IPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLPDHSAATKPSLFLFLVSL 437
           IPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLPDHSAATKPSLFLFLVSL
Sbjct: 361 IPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLPDHSAATKPSLFLFLVSL 420

Query: 438 LHIFFK 443
           LHIFFK
Sbjct: 421 LHIFFK 426


>1QMU-A nrPDB
          Length = 380

 Score =  365 bits (937), Expect = e-101,   Method: Compositional matrix adjust.
 Identities = 187/367 (50%), Positives = 247/367 (67%), Gaps = 10/367 (2%)

Query: 15  VAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIP 74
           V  +DF +H    ME FL+  A  Y S+T L+S+GKSV+ R L+V+ +   P  H  G P
Sbjct: 3   VQPVDFRHHHFSDMEIFLRRYANEYPSITRLYSVGKSVELRELYVMEISDNPGIHEAGEP 62

Query: 75  EFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVK 134
           EFKY+ NMHG+E VGRELLL+LI+YL  + G DPE+T+L+ STRIHIMPSMNPDG+E  +
Sbjct: 63  EFKYIGNMHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVQSTRIHIMPSMNPDGYEKSQ 122

Query: 135 KPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGAL 194
           + D   ++GR N N YDLNRNFPD F       QPET+AVM WLKT  FVLSANLHGG+L
Sbjct: 123 EGDRGGTVGRNNSNNYDLNRNFPDQFFQVTDPPQPETLAVMSWLKTYPFVLSANLHGGSL 182

Query: 195 VASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKN---KMNFPNG 251
           V +YPFD+  Q   A+YS+S  PDD VFQ LA +Y+  N  M +G  CK+      FP+G
Sbjct: 183 VVNYPFDDDEQGI-AIYSKS--PDDAVFQQLALSYSKENKKMYQGSPCKDLYPTEYFPHG 239

Query: 252 VTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQV 311
           +TNG  WY + GGMQD+NY+   CFE+T+EL C KYP+ E+LP +W  N+ SL+++IKQV
Sbjct: 240 ITNGAQWYNVPGGMQDWNYLNTNCFEVTIELGCVKYPKAEELPKYWEQNRRSLLQFIKQV 299

Query: 312 HLGVKGQVFDQ-NGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHD 370
           H G+ G V D  +G  + N  + V D  H  P  T K G+Y+ LL+ G+Y +  +  G+D
Sbjct: 300 HRGIWGFVLDATDGRGILNATISVADINH--PVTTYKDGDYWRLLVQGTYKVTASARGYD 357

Query: 371 PHITKVI 377
           P +TK +
Sbjct: 358 P-VTKTV 363


>3MN8-A nrPDB
          Length = 435

 Score =  323 bits (829), Expect = 6e-89,   Method: Compositional matrix adjust.
 Identities = 169/396 (42%), Positives = 246/396 (62%), Gaps = 21/396 (5%)

Query: 21  NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
           +Y  QE +E     + + Y +   +H +G+S++GRNL  L + R  +   +  P  KY+A
Sbjct: 39  HYASQEQLEDLFAGLEKAYPNQAKVHFLGRSLEGRNLLALQISRNTRSRNLLTPPVKYIA 98

Query: 81  NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
           NMHGDETVGR+LL+++  YL+ +  +  ++  L+NST I+++P+MNPDG+   ++ +C  
Sbjct: 99  NMHGDETVGRQLLVYMAQYLLGNHERISDLGQLVNSTDIYLVPTMNPDGYALSQEGNCES 158

Query: 141 ---SIGRENYNQYDLNRNFPDAFEYNNV------SRQPETVAVMKWLKTETFVLSANLHG 191
               +GR N    DLNR+FPD  E ++V      SRQPET A++ W+ ++ FVLSAN HG
Sbjct: 159 LPNYVGRGNAANIDLNRDFPDRLEQSHVHQLRAQSRQPETAALVNWIVSKPFVLSANFHG 218

Query: 192 GALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNG 251
           GA+VASYP+DN + A       SLTPDD VF+ LAHTY+  +P M+KG+ C +  +F  G
Sbjct: 219 GAVVASYPYDNSL-AHNECCEESLTPDDRVFKQLAHTYSDNHPIMRKGNNCND--SFSGG 275

Query: 252 VTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQV 311
           +TNG  WY L GGMQD+NY ++ CFE+T+ELSCCKYP    LP  W  NKASL++ ++Q 
Sbjct: 276 ITNGAHWYELSGGMQDFNYAFSNCFELTIELSCCKYPAASTLPQEWQRNKASLLQLLRQA 335

Query: 312 HLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHD- 370
           H+G+KG V D +G P+ +  V V   +   P RT+K GEY+ LL PG Y ++ +  G+  
Sbjct: 336 HIGIKGLVTDASGFPIADANVYVAGLEEK-PMRTSKRGEYWRLLTPGLYSVHASAFGYQT 394

Query: 371 --PHITKVIIPEKSQNFSALKKDI-LLPFQGQLDSI 403
             P   +V     + N  AL+ D  L P +   D I
Sbjct: 395 SAPQQVRVT----NDNQEALRLDFKLAPVETNFDGI 426


>2NSM-A nrPDB
          Length = 439

 Score =  301 bits (770), Expect = 5e-82,   Method: Compositional matrix adjust.
 Identities = 172/391 (43%), Positives = 232/391 (59%), Gaps = 38/391 (9%)

Query: 18  LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77
           L F +HR + +   L  V      +T ++SIG+SV+GR+L+VL     P  H    PE K
Sbjct: 2   LAFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVK 61

Query: 78  YVANMHGDETVGRELLLHLIDYLVTS-DGKDPEITNLINSTRIHIMPSMNPDGFE--AVK 134
           YV NMHG+E +GREL+L L ++L      ++  I  LI  TRIHI+PSMNPDG+E  A +
Sbjct: 62  YVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQ 121

Query: 135 KPDC-YYSIGRENYNQYDLNRNFPDAFEY-----------------NNVSRQ--PETVAV 174
            P+   Y +GR N N  DLNRNFPD   Y                 +N   Q  PET AV
Sbjct: 122 GPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLPDNWKSQVEPETRAV 181

Query: 175 MKWLKTETFVLSANLHGGALVASYPFD-------NGVQATGALYSRSLTPDDDVFQYLAH 227
           ++W+ +  FVLSANLHGGA+VA+YP+D        GV+ T +    + TPDD +FQ LA 
Sbjct: 182 IRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTAS----TPTPDDKLFQKLAK 237

Query: 228 TYASRNPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKY 287
            Y+  +  M +G  C +   FP+G+TNG SWY L  GMQD+NY+   CFEITLELSC K+
Sbjct: 238 VYSYAHGWMFQGWNCGDY--FPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKF 295

Query: 288 PREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNK 347
           P EE+L   W  NK +LI++++QVH G+KG V DQN N L N ++ V    H     +  
Sbjct: 296 PPEEELQREWLGNKEALIQFLEQVHQGIKGMVLDQNYNNLANAVISVSGINHDVT--SGD 353

Query: 348 YGEYYLLLLPGSYIINVTVPGHDPHITKVII 378
           +G+Y+ LLLPG Y ++ T PG+DP    V +
Sbjct: 354 HGDYFRLLLPGIYTVSATAPGYDPETVTVTV 384


>3V7Z-A nrPDB
          Length = 326

 Score = 72.0 bits (175), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 78/308 (25%), Positives = 122/308 (39%), Gaps = 65/308 (21%)

Query: 17  ALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGI--- 73
           + D  YH    M   + TVA NY ++    SIGKS +GR LW + +        +G    
Sbjct: 4   SYDSGYHNYNEMVNKINTVASNYPNIVKKFSIGKSYEGRELWAVKIS-----DNVGTDEN 58

Query: 74  -PEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEA 132
            PE  Y A  H  E +  E+ L+ +D    +   D  ITNL+N+  I+I+ ++NPDG E 
Sbjct: 59  EPEVLYTALHHAREHLTVEMALYTLDLFTQNYNLDSRITNLVNNREIYIVFNINPDGGEY 118

Query: 133 VKKPDCYYSIGR-------ENYNQYDLNRNF---------------PDAFEYNNVSRQPE 170
                 Y S  +        +Y   DLNRN+                + +   +    PE
Sbjct: 119 DISSGSYKSWRKNRQPNSGSSYVGTDLNRNYGYKWGCCGGSSGSPSSETYRGRSAFSAPE 178

Query: 171 TVAVMKWLKTETFVLSANLHGGALVASYPFDNGV-QATGALYS---RSLTPDD-DVFQYL 225
           T A+  ++ +   V+        L+  + +   +    G  Y+     +T DD +VF+ +
Sbjct: 179 TAAMRDFINSR--VVGGKQQIKTLITFHTYSELILYPYGYTYTDVPSDMTQDDFNVFKTM 236

Query: 226 AHTYASRNPNMKKGDECKNKMNFPNGVTNGYS------WYPLQGGMQDYNYIWAQCFEIT 279
           A+T A                      TNGY+       Y   G M D+ Y   + F  T
Sbjct: 237 ANTMAQ---------------------TNGYTPQQASDLYITDGDMTDWAYGQHKIFAFT 275

Query: 280 LELSCCKY 287
            E+    Y
Sbjct: 276 FEMYPTSY 283


>4A39-A nrPDB
          Length = 388

 Score = 53.5 bits (127), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 41/145 (28%), Positives = 67/145 (46%), Gaps = 18/145 (12%)

Query: 47  SIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGK 106
           ++G SV+GR++ +L V R P  H     +   +A  H  E +    +  LI+ L   D  
Sbjct: 148 AVGTSVQGRDIELLRVRRHPDSHL----KLWVIAQQHPGEHMAEWFMEGLIERLQRPD-- 201

Query: 107 DPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVS 166
           D E+  L+    ++++P+MNPDG         ++   R N    DLNR    A+   +  
Sbjct: 202 DTEMQRLLEKADLYLVPNMNPDG--------AFHGNLRTNAAGQDLNR----AWLEPSAE 249

Query: 167 RQPETVAVMKWLKTETFVLSANLHG 191
           R PE   V + +K     L  ++HG
Sbjct: 250 RSPEVWFVQQEMKRHGVDLFLDIHG 274


>1KWM-A nrPDB
          Length = 402

 Score = 49.3 bits (116), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 57/282 (20%), Positives = 107/282 (37%), Gaps = 42/282 (14%)

Query: 22  YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
           Y++ E +EA+ + VA    ++     IG + +GR +++L VG+  +      P       
Sbjct: 104 YNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNK----PAIFMDCG 159

Query: 82  MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
            H  E +        +   V + G++ ++T L+N    +++P +N DG+        ++ 
Sbjct: 160 FHAREWISPAFCQWFVREAVRTYGREIQVTELLNKLDFYVLPVLNIDGYIYTWTKSRFWR 219

Query: 142 IGRENYN-----QYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTET 182
             R  +        D NRNF   +     SR P              ET A+  +++ + 
Sbjct: 220 KTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKL 279

Query: 183 FVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD 240
             + A   +H  + +  YP+          Y+  L  ++     LA        ++    
Sbjct: 280 SSIKAYLTIHSYSQMMIYPYS---------YAYKLGENNAELNALAKATVKELASLH--- 327

Query: 241 ECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
               K  +  G T   + YP  GG  D+ Y     +  T EL
Sbjct: 328 --GTKYTYGPGAT---TIYPAAGGSDDWAYDQGIRYSFTFEL 364


>1ZLI-A nrPDB
          Length = 309

 Score = 48.5 bits (114), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 57/282 (20%), Positives = 106/282 (37%), Gaps = 42/282 (14%)

Query: 22  YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
           Y+  E +EA+ + VA    ++     IG + +GR +++L VG+  +      P       
Sbjct: 11  YNNWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNK----PAIFMDCG 66

Query: 82  MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
            H  E +        +   V + G++ ++T L+N    +++P +N DG+        ++ 
Sbjct: 67  FHAREWISPAFCQWFVREAVRTYGREIQVTELLNKLDFYVLPVLNIDGYIYTWTKSRFWR 126

Query: 142 IGRENYN-----QYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTET 182
             R  +        D NRNF   +     SR P              ET A+  +++ + 
Sbjct: 127 KTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKL 186

Query: 183 FVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD 240
             + A   +H  + +  YP+          Y+  L  ++     LA        ++    
Sbjct: 187 SSIKAYLTIHSYSQMMIYPYS---------YAYKLGENNAELNALAKATVKELASLH--- 234

Query: 241 ECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
               K  +  G T   + YP  GG  D+ Y     +  T EL
Sbjct: 235 --GTKYTYGPGAT---TIYPAAGGSDDWAYDQGIRYSFTFEL 271


>4BD9-A nrPDB
          Length = 310

 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 36/159 (22%), Positives = 67/159 (42%), Gaps = 11/159 (6%)

Query: 19  DFNYHRQEGMEAF---LKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75
           +FNY     +EA    +  +A ++  +     IG S + R ++VL   +F     +  P 
Sbjct: 6   NFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVL---KFSTGKGVRRPA 62

Query: 76  FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135
               A +H  E + +   +     +V+   +DP IT+++    I ++P  NPDG+   + 
Sbjct: 63  VWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQT 122

Query: 136 PDCYYSIGR-----ENYNQYDLNRNFPDAFEYNNVSRQP 169
            +  +   R      +    D NRN+  +F     S  P
Sbjct: 123 QNRLWRKTRSRNPGSSCIGADPNRNWNASFAGKGASDNP 161


>2BOA-A nrPDB
          Length = 404

 Score = 45.4 bits (106), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 28/115 (24%), Positives = 53/115 (46%), Gaps = 6/115 (5%)

Query: 19  DFNYHRQEGMEAF---LKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75
           +FNY     +EA    +  +A ++  +     IG S + R ++VL   +F     +  P 
Sbjct: 100 NFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVL---KFSTGKGVRRPA 156

Query: 76  FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGF 130
               A +H  E + +   +     +V+   +DP IT+++    I ++P  NPDG+
Sbjct: 157 VWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGY 211


>3OSL-A nrPDB
          Length = 401

 Score = 45.1 bits (105), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 62/284 (21%), Positives = 110/284 (38%), Gaps = 41/284 (14%)

Query: 21  NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
            YH    + ++++ + + Y  +     IG S +   L+VL V +  KE R     +    
Sbjct: 100 QYHSLNEIYSWIEVMTERYPDMVEKIHIGSSYEKYPLYVLKVSK--KEQRAKNAMW-IDC 156

Query: 81  NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
            +H  E +     L  +  +    GK+   TNL+     +IMP +N DG++   K D  +
Sbjct: 157 GIHAREWISPAFCLWFVGSVTYYYGKEKMHTNLLKHMDFYIMPVVNVDGYDYTWKKDRMW 216

Query: 141 SIGRENYNQ-----YDLNRNFP------DAFEYNNVSR---------QPETVAVMKWLKT 180
              R  + +      DLNRNF       +    ++ S          +PE  AV  +L+ 
Sbjct: 217 RKNRSLHEKNACVGTDLNRNFASKHWCGEGASSSSCSEIYCGTYPESEPEVKAVADFLRR 276

Query: 181 ETFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKK 238
               + A  ++H  +    +P+          YSRS + D +    +A        N+ +
Sbjct: 277 NIKHIKAYISMHSYSQKIVFPYS---------YSRSRSKDHEELSLVAREAVFAMENIHR 327

Query: 239 GDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
                  + + +G +   S Y   GG  D+ Y     +  T EL
Sbjct: 328 N------IRYTHG-SGSESLYLAPGGSDDWIYDLGIKYSFTFEL 364


>4B6Z-A nrPDB
          Length = 405

 Score = 44.7 bits (104), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 50/179 (27%), Positives = 77/179 (43%), Gaps = 27/179 (15%)

Query: 20  FNYHRQEGMEAFLKTVAQ-NYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKY 78
           F  + +E   AFL  V Q   +SV  L   G++V+GR + +L +G    +   G P+ K 
Sbjct: 132 FEPYSEERHAAFLGAVQQLPQASVVEL---GRTVEGRPMSLLTLGTPETD---GAPKKKV 185

Query: 79  --VANMHGDETVGRELLLHLIDYLVTSD--GKDPEITNLINSTRIHIMPSMNPDGFEAVK 134
             +A  H  E++    +  L+  L        DP    L +    HI+P+MNPDG     
Sbjct: 186 WIIARQHPGESMAEWFVEGLVKRLAGWGDWAGDPVARKLYDRVTFHIVPNMNPDG----- 240

Query: 135 KPDCYYSIGRENYNQYDLNRNF--PDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHG 191
                +   R N    +LNR +  PDA       R PE +AV   +      +  ++HG
Sbjct: 241 ---SVHGNLRTNAAGANLNREWMAPDA------ERSPEVLAVRDAIHAIGCDMFFDIHG 290


>3D4U-A nrPDB
          Length = 309

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 62/284 (21%), Positives = 110/284 (38%), Gaps = 41/284 (14%)

Query: 21  NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
            YH    + ++++ + + Y  +     IG S +   L+VL V +  KE R     +    
Sbjct: 8   QYHSLNEIYSWIEVMTERYPDMVEKIHIGSSYEKYPLYVLKVSK--KEQRAKNAMW-IDC 64

Query: 81  NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
            +H  E +     L  +  +    GK+   TNL+     +IMP +N DG++   K D  +
Sbjct: 65  GIHAREWISPAFCLWFVGSVTYYYGKEKMHTNLLKHMDFYIMPVVNVDGYDYTWKKDRMW 124

Query: 141 SIGRENYNQ-----YDLNRNFP------DAFEYNNVSR---------QPETVAVMKWLKT 180
              R  + +      DLNRNF       +    ++ S          +PE  AV  +L+ 
Sbjct: 125 RKNRSLHEKNACVGTDLNRNFASKHWCGEGASSSSCSEIYCGTYPESEPEVKAVADFLRR 184

Query: 181 ETFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKK 238
               + A  ++H  +    +P+          YSRS + D +    +A        N+ +
Sbjct: 185 NIKHIKAYISMHSYSQKIVFPYS---------YSRSRSKDHEELSLVAREAVFAMENIHR 235

Query: 239 GDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
                  + + +G +   S Y   GG  D+ Y     +  T EL
Sbjct: 236 N------IRYTHG-SGSESLYLAPGGSDDWIYDLGIKYSFTFEL 272


>1DTD-A nrPDB
          Length = 303

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 36/154 (23%), Positives = 63/154 (40%), Gaps = 11/154 (7%)

Query: 22  YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
           YH  E +   +  +   +  +    +IG S + R + VL       +     P     A 
Sbjct: 6   YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-----PAIWLDAG 60

Query: 82  MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
           +H  E V +   L   + +V+  GKDP IT+++++  I ++P  NPDG+   +  +  + 
Sbjct: 61  IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR 120

Query: 142 IGRENYNQ------YDLNRNFPDAFEYNNVSRQP 169
             R   +        D NRN+   F     S  P
Sbjct: 121 KTRSKVSAGSLCVGVDPNRNWDAGFGGPGASSNP 154


>1JQG-A nrPDB
          Length = 433

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 53/218 (24%), Positives = 85/218 (38%), Gaps = 43/218 (19%)

Query: 23  HRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN- 81
           H  E ++A+L+ +A+ + +V  +   GKS +GR++         K  RI    F+  +  
Sbjct: 122 HSYEEVDAYLQELAKEFPNVVTVVEGGKSFEGRSI---------KYLRISTTNFQDASKP 172

Query: 82  -------MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVK 134
                  +H  E V     L+ I  LV     D   ++LIN+    I+P  NPDG+    
Sbjct: 173 VVMMQSLLHCREWVTLPATLYAIHKLVI----DVTESDLINNIDWIILPVANPDGYVHTF 228

Query: 135 KPDCYYSIGRENYNQ-------YDLNRNF-------------PDAFEYNNVSRQPETVAV 174
             D Y+   R             DLNRNF              D F   +   +PE+  +
Sbjct: 229 GGDRYWRKNRATGYMAGNLCMGVDLNRNFGMNWGTASSSSVCSDTFHGRSAFSEPESSVI 288

Query: 175 MKWLKTE--TFVLSANLHGGALVASYPFDNGVQATGAL 210
              +        L  ++H    +  Y + NGV  + AL
Sbjct: 289 RDIIAEHRNRMALYLDIHSFGSMILYGYGNGVLPSNAL 326


>3K2K-A nrPDB
          Length = 403

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 48/177 (27%), Positives = 75/177 (42%), Gaps = 23/177 (12%)

Query: 20  FNYHRQEGMEAFLKTVAQN-YSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKY 78
           F  + +E    FL  V Q   +SV  L   G++V+GR + ++V+G  P E      +   
Sbjct: 130 FEPYSEERHSEFLGAVQQMPQASVVEL---GRTVEGRPMSLVVLGT-PDEAGAAKKKVWI 185

Query: 79  VANMHGDETVGRELLLHLIDYLVTSD--GKDPEITNLINSTRIHIMPSMNPDGFEAVKKP 136
           +A  H  E++    +  L+  LV       DP    L +    +I+P+MNPDG       
Sbjct: 186 IARQHPGESMAEWFIEGLVKRLVGWGDWSGDPVARKLYDHATFYIVPNMNPDG------- 238

Query: 137 DCYYSIGRENYNQYDLNRNF--PDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHG 191
              +   R N    +LNR +  PDA       R PE + V   +      L  ++HG
Sbjct: 239 -SVHGNLRTNAAGANLNREWMEPDA------ERSPEVLVVRDAIHAIGCDLFFDIHG 288


>1AYE-A nrPDB
          Length = 401

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 36/153 (23%), Positives = 63/153 (41%), Gaps = 10/153 (6%)

Query: 22  YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
           YH  E +   +  +   +  +    +IG S + R + VL       +     P     A 
Sbjct: 105 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-----PAIWLDAG 159

Query: 82  MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
           +H  E V +   L   + +V+  GKDP IT+++++  I ++P  NPDG+   +  +  + 
Sbjct: 160 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR 219

Query: 142 IGRENYN-----QYDLNRNFPDAFEYNNVSRQP 169
             R   +       D NRN+   F     S  P
Sbjct: 220 KTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNP 252


>5AQ0-A nrPDB
          Length = 82

 Score = 40.8 bits (94), Expect = 0.001,   Method: Composition-based stats.
 Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 4/69 (5%)

Query: 314 GVKGQVFDQ-NGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDP- 371
           GVKG V D   G+ L N  + V    H     T ++G++Y LL+PG+Y + V + G+ P 
Sbjct: 2   GVKGFVKDSITGSGLENATISVAGINH--NITTGRFGDFYRLLVPGTYNLTVVLTGYMPL 59

Query: 372 HITKVIIPE 380
            +T V++ E
Sbjct: 60  TVTNVVVKE 68


>4UIB-A nrPDB
          Length = 307

 Score = 40.4 bits (93), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 25/109 (22%), Positives = 49/109 (44%), Gaps = 4/109 (3%)

Query: 22  YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
           Y+  E +EA+ K V      +    +IG +  G N+++L VG+ P  ++   P       
Sbjct: 9   YNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGK-PGPNK---PAIFMDCG 64

Query: 82  MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGF 130
           +H  E +        +   V + G +  +T  +N    +++P +N DG+
Sbjct: 65  IHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGY 113


>3GLJ-A nrPDB
          Length = 401

 Score = 38.9 bits (89), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 25/109 (22%), Positives = 48/109 (44%), Gaps = 4/109 (3%)

Query: 22  YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
           Y+  E +EA+ K V      +    +IG +  G N+++L VG+ P  ++   P       
Sbjct: 104 YNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGK-PGPNK---PAIFMDCG 159

Query: 82  MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGF 130
            H  E +        +   V + G +  +T  +N    +++P +N DG+
Sbjct: 160 FHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGY 208


>1NSA-A nrPDB
          Length = 395

 Score = 38.5 bits (88), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 23/109 (21%), Positives = 50/109 (45%), Gaps = 4/109 (3%)

Query: 22  YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
           Y+  E +EA+ + V      +    +IG +  G N+++L VG+ P  ++   P       
Sbjct: 98  YNNWETIEAWTEQVTSKNPDLISRSAIGTTFDGDNIYLLKVGK-PGSNK---PAIFMDCG 153

Query: 82  MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGF 130
            H  E + +      +   V + G +  +T  +++   +++P +N DG+
Sbjct: 154 FHAREWISQAFCQWFVRDAVRTYGYEAHMTEFLDNLDFYVLPVLNIDGY 202


>3KGQ-A nrPDB
          Length = 309

 Score = 36.2 bits (82), Expect = 0.027,   Method: Compositional matrix adjust.
 Identities = 32/154 (20%), Positives = 55/154 (35%), Gaps = 9/154 (5%)

Query: 21  NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
            YH  + +  F+  +   +  +     IG+S +GR ++VL             P      
Sbjct: 11  TYHTLDEIYDFMDLLVAEHPQLVSKLQIGRSYEGRPIYVLKFSTGGSNR----PAIWIDL 66

Query: 81  NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
            +H  E + +   +          G+DP  T +++S  I +    NPDGF      +  +
Sbjct: 67  GIHSREWITQATGVWFAKKFTEDYGQDPSFTAILDSMDIFLEIVTNPDGFAFTHSQNRLW 126

Query: 141 SIGRENYNQ-----YDLNRNFPDAFEYNNVSRQP 169
              R   +       D NRN+   F     S  P
Sbjct: 127 RKTRSVTSSSLCVGVDANRNWDAGFGKAGASSSP 160


>3L2N-A nrPDB
          Length = 395

 Score = 36.2 bits (82), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 25/83 (30%), Positives = 44/83 (53%), Gaps = 8/83 (9%)

Query: 48  IGKSVKGRNLWVLVVGRF-PKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGK 106
           +G ++ GR++ ++ VG   P +  I I      A  H  ET+   L+  L++ L+ +D  
Sbjct: 154 LGLTLDGRDMTLVKVGDDDPSKKSIWI-----TARQHPGETMAEWLVEGLLNQLLDNDC- 207

Query: 107 DPEITNLINSTRIHIMPSMNPDG 129
            P    L++    +I+P+MNPDG
Sbjct: 208 -PTSKALLDKANFYIVPNMNPDG 229


>3D68-A nrPDB
          Length = 424

 Score = 35.0 bits (79), Expect = 0.068,   Method: Compositional matrix adjust.
 Identities = 34/143 (23%), Positives = 61/143 (42%), Gaps = 10/143 (6%)

Query: 21  NYHRQEGMEAFLKTVAQNY-SSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79
            YH    + ++++ + + +   +T +H IG S +   L+VL V    +  +  I      
Sbjct: 123 QYHSLNEIYSWIEFITERHPDMLTKIH-IGSSFEKYPLYVLKVSGKEQTAKNAI---WID 178

Query: 80  ANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCY 139
             +H  E +     L  I ++    G   + TNL+     ++MP +N DG++   K +  
Sbjct: 179 CGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRM 238

Query: 140 YSIGRENYNQ-----YDLNRNFP 157
           +   R  Y        DLNRNF 
Sbjct: 239 WRKNRSFYANNHCIGTDLNRNFA 261


>3LMS-A nrPDB
          Length = 309

 Score = 35.0 bits (79), Expect = 0.072,   Method: Compositional matrix adjust.
 Identities = 34/144 (23%), Positives = 61/144 (42%), Gaps = 10/144 (6%)

Query: 21  NYHRQEGMEAFLKTVAQNY-SSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79
            YH    + ++++ + + +   +T +H IG S +   L+VL V    +  +  I      
Sbjct: 8   QYHSLNEIYSWIEFITERHPDMLTKIH-IGSSFEKYPLYVLKVSGKEQAAKNAIW---ID 63

Query: 80  ANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCY 139
             +H  E +     L  I ++    G   + TNL+     ++MP +N DG++   K +  
Sbjct: 64  CGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRM 123

Query: 140 YSIGRENYNQ-----YDLNRNFPD 158
           +   R  Y        DLNRNF  
Sbjct: 124 WRKNRSFYANNHCIGTDLNRNFAS 147


>4UEE-A nrPDB
          Length = 309

 Score = 33.5 bits (75), Expect = 0.18,   Method: Compositional matrix adjust.
 Identities = 36/155 (23%), Positives = 60/155 (38%), Gaps = 11/155 (7%)

Query: 21  NYHRQEGMEAFLKT-VAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79
            YH  E +  FL   VA+N   V+ +  IG + +GR ++VL       +     P     
Sbjct: 11  TYHTLEEIYDFLDLLVAENPHLVSKIQ-IGNTYEGRPIYVLKFSTGGSKR----PAIWID 65

Query: 80  ANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCY 139
             +H  E V +   +     +    G+D   T ++++  I +    NPDGF      +  
Sbjct: 66  TGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRM 125

Query: 140 YSIGRENYN-----QYDLNRNFPDAFEYNNVSRQP 169
           +   R +         D NRN+   F  +  S  P
Sbjct: 126 WRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNP 160


>2QVP-A nrPDB
          Length = 275

 Score = 33.5 bits (75), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 19/62 (30%), Positives = 30/62 (48%), Gaps = 9/62 (14%)

Query: 69  HRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPD 128
            + G+P     A  HG+E+ G   LLH +  L      D E+   +N   + ++P +NP 
Sbjct: 61  QKAGLPNLLISAGFHGEESAGPWGLLHFLSQL------DGELFKRVN---LSVLPLVNPT 111

Query: 129 GF 130
           GF
Sbjct: 112 GF 113


>5MRV-A nrPDB
          Length = 355

 Score = 33.5 bits (75), Expect = 0.21,   Method: Compositional matrix adjust.
 Identities = 33/179 (18%), Positives = 72/179 (40%), Gaps = 22/179 (12%)

Query: 22  YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
           YH    +  +++ +++ Y  V   H +G + +   ++ L + + P  +   I        
Sbjct: 56  YHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPIYYLKISQ-PSGNPKKIIWMD--CG 112

Query: 82  MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
           +H  E +        +  ++ +   +  I  L+ +   +++P +N DG+      D  + 
Sbjct: 113 IHAREWIAPAFCQWFVKEILQNHKDNSRIRKLLRNLDFYVLPVLNIDGYIYTWTTDRLWR 172

Query: 142 IGRENYNQ-----YDLNRNFPDAFEYNNVSR--------------QPETVAVMKWLKTE 181
             R  +N       DLNRNF  ++     SR              +PET AV  +++++
Sbjct: 173 KSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVASFIESK 231


>5OM9-A nrPDB
          Length = 419

 Score = 32.7 bits (73), Expect = 0.29,   Method: Compositional matrix adjust.
 Identities = 36/155 (23%), Positives = 60/155 (38%), Gaps = 11/155 (7%)

Query: 21  NYHRQEGMEAFLKT-VAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79
            YH  E +  FL   VA+N   V+ +  IG + +GR ++VL       +     P     
Sbjct: 121 TYHTLEEIYDFLDLLVAENPHLVSKIQ-IGNTYEGRPIYVLKFSTGGSKR----PAIWID 175

Query: 80  ANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCY 139
             +H  E V +   +     +    G+D   T ++++  I +    NPDGF      +  
Sbjct: 176 TGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRM 235

Query: 140 YSIGRENYN-----QYDLNRNFPDAFEYNNVSRQP 169
           +   R +         D NRN+   F  +  S  P
Sbjct: 236 WRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNP 270


>1PCA-A nrPDB
          Length = 403

 Score = 32.0 bits (71), Expect = 0.53,   Method: Compositional matrix adjust.
 Identities = 30/154 (19%), Positives = 58/154 (37%), Gaps = 9/154 (5%)

Query: 21  NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
            YH  E +  F+  +   + ++     IG+S +GR ++VL             P     +
Sbjct: 106 TYHTLEEIYDFMDILVAEHPALVSKLQIGRSYEGRPIYVLKFSTGGSNR----PAIWIDS 161

Query: 81  NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
            +H  E + +   +     +  + G++   T +++S  I +    NP+GF      +  +
Sbjct: 162 GIHSREWITQASGVWFAKKITENYGQNSSFTAILDSMDIFLEIVTNPNGFAFTHSDNRLW 221

Query: 141 SIGRENYN-----QYDLNRNFPDAFEYNNVSRQP 169
              R   +       D NRN+   F     S  P
Sbjct: 222 RKTRSKASGSLCVGSDSNRNWDAGFGGAGASSSP 255


>5HXD-A nrPDB
          Length = 237

 Score = 32.0 bits (71), Expect = 0.60,   Method: Compositional matrix adjust.
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 17/63 (26%)

Query: 118 RIHIMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDA--------FEYNNVSRQP 169
           R H++  +NPDG        C   + R N N  DLNRNFP A        + +N+ + + 
Sbjct: 72  RHHVVLCVNPDG--------CQLGL-RANANGVDLNRNFPAANWKEGETVYRWNSAAEER 122

Query: 170 ETV 172
           + V
Sbjct: 123 DVV 125


>4GFJ-A nrPDB
          Length = 685

 Score = 31.2 bits (69), Expect = 0.86,   Method: Compositional matrix adjust.
 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 4/73 (5%)

Query: 29  EAF-LKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEH-RIGIPEFKYVANMHGDE 86
           EAF L+T A+ Y     L  IG+ +   +L  L +G  PK    I  PEFK++ N+ G  
Sbjct: 574 EAFDLETAAELYERYGSLKEIGRRLSYDDL--LELGATPKAAAEIKGPEFKFLLNIEGVG 631

Query: 87  TVGRELLLHLIDY 99
               E +L  +DY
Sbjct: 632 PKLAERILEAVDY 644


>5HM5-A nrPDB
          Length = 854

 Score = 31.2 bits (69), Expect = 0.97,   Method: Compositional matrix adjust.
 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 4/73 (5%)

Query: 29  EAF-LKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEH-RIGIPEFKYVANMHGDE 86
           EAF L+T A+ Y     L  IG+ +   +L  L +G  PK    I  PEFK++ N+ G  
Sbjct: 574 EAFDLETAAELYERYGSLKEIGRRLSYDDL--LELGATPKAAAEIKGPEFKFLLNIEGVG 631

Query: 87  TVGRELLLHLIDY 99
               E +L  +DY
Sbjct: 632 PKLAERILEAVDY 644


>3IEH-A nrPDB
          Length = 276

 Score = 31.2 bits (69), Expect = 1.0,   Method: Compositional matrix adjust.
 Identities = 29/127 (22%), Positives = 43/127 (33%), Gaps = 20/127 (15%)

Query: 70  RIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDG 129
           + G+P     A  HG+E+ G   LLH +              +L     + ++P +NP G
Sbjct: 63  KSGLPSLLISAGFHGEESAGPWGLLHFL---------SEASADLFERVNLSLLPLVNPTG 113

Query: 130 FEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANL 189
           F    +           +N+Y  N N    FE         T    K L     +L A  
Sbjct: 114 FSRGHR-----------FNKYGENPNRGFVFENGKPKANEHTSVEGKLLLDHAQLLIAAC 162

Query: 190 HGGALVA 196
             G L  
Sbjct: 163 RDGILTC 169


>2C1C-A nrPDB
          Length = 312

 Score = 30.0 bits (66), Expect = 2.2,   Method: Compositional matrix adjust.
 Identities = 38/183 (20%), Positives = 71/183 (38%), Gaps = 20/183 (10%)

Query: 21  NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVG--RFPKEHRIGIPEFKY 78
           NY   E ++ +L  + + Y  V  + +  +S +GR +  + +    F  E++   P    
Sbjct: 5   NYQELEVIDEYLDYIGEKYPDVATVVNAAESFEGRPIKYIKISTTNFEDENK---PVIFI 61

Query: 79  VANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDC 138
              +H  E +    +   I  LV    +D    +L+      ++P +NPDG++     + 
Sbjct: 62  DGGIHAREWISPPSVTWAIHKLV----EDVTENDLLEKFDWILLPVVNPDGYKYTFTNER 117

Query: 139 YYSIGRENYNQ--------YDLNRNFPDAFEYNNVSRQPET---VAVMKWLKTETFVLSA 187
           ++   R   N          D NRNF   +     S  P +        + + ET V+  
Sbjct: 118 FWRKTRSTNNNPLSQICRGADGNRNFDFVWNSIGTSNSPCSDIYAGTSAFSEVETRVVRD 177

Query: 188 NLH 190
            LH
Sbjct: 178 ILH 180


>6D97-A nrPDB
          Length = 547

 Score = 29.6 bits (65), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 36/151 (23%), Positives = 64/151 (42%), Gaps = 16/151 (10%)

Query: 255 GYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLG 314
           G+ W  L   +Q+ +Y+   C +     S  K   +  L    N + + L+E +K+  L 
Sbjct: 296 GFDWKILGPDVQEVDYVAWVCDQDAYACSGQKCSAQSVLFMHKNWSSSGLLEKMKK--LS 353

Query: 315 VKGQVFDQNGNPLPNVIVE--VQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVP----G 368
            + ++ D    P+  V  E  ++   ++   R +K      +L  G  + N ++P     
Sbjct: 354 ERRKLEDLTIGPVLTVTTEAMIEHMNNLLKIRGSK------VLFGGEPLANHSIPKIYGA 407

Query: 369 HDPHITKVIIPE--KSQNFSALKKDILLPFQ 397
             P    V + E  KS NF  + K+I  PFQ
Sbjct: 408 MKPTAVFVPLEEILKSGNFELVTKEIFGPFQ 438


>3B2Y-A nrPDB
          Length = 275

 Score = 29.3 bits (64), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 17/64 (26%), Positives = 29/64 (45%), Gaps = 9/64 (14%)

Query: 69  HRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPD 128
            R  +P     +  HG+E  G   +LH +       G  P +   +N   + ++P +NP 
Sbjct: 62  QRSDLPSLLISSGFHGEEAAGPWGMLHFLR------GLQPALFERVN---LSLLPLVNPT 112

Query: 129 GFEA 132
           GF+A
Sbjct: 113 GFKA 116


>3N5M-A nrPDB
          Length = 452

 Score = 28.5 bits (62), Expect = 6.5,   Method: Compositional matrix adjust.
 Identities = 34/135 (25%), Positives = 50/135 (37%), Gaps = 24/135 (17%)

Query: 128 DGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTET---FV 184
            GF  V  PDCY   G E  N YD             V    E   VM W  +ET   F+
Sbjct: 174 SGFLHVTPPDCYRMPGIERENIYD-------------VECVKEVDRVMTWELSETIAAFI 220

Query: 185 LSANLHGGA-LVASYPFDNGVQATGALYSRSLTPDDDV--FQYLAHTYASRNPNMKKGDE 241
           +   + GG  L+A   +   V  T   +   L  D+ +  F      +   N ++K    
Sbjct: 221 MEPIITGGGILMAPQDYMKAVHETCQKHGALLISDEVICGFGRTGKAFGFMNYDVK---- 276

Query: 242 CKNKMNFPNGVTNGY 256
             + +    G+T+ Y
Sbjct: 277 -PDIITMAKGITSAY 290


>1SEZ-A nrPDB
          Length = 504

 Score = 28.1 bits (61), Expect = 8.8,   Method: Compositional matrix adjust.
 Identities = 17/57 (29%), Positives = 27/57 (47%), Gaps = 3/57 (5%)

Query: 192 GALVASYPFDNGVQATGALYSRSLTPD---DDVFQYLAHTYASRNPNMKKGDECKNK 245
           G LV S    +G++  G L+S  + PD   ++V+ Y      SRN  + K    + K
Sbjct: 354 GVLVPSKEQQHGLKTLGTLFSSMMFPDRAPNNVYLYTTFVGGSRNRELAKASRTELK 410


>1YKN-B nrPDB
          Length = 238

 Score = 27.7 bits (60), Expect = 9.4,   Method: Compositional matrix adjust.
 Identities = 11/20 (55%), Positives = 15/20 (75%)

Query: 315 VKGQVFDQNGNPLPNVIVEV 334
           V G+V DQ G P+PN +VE+
Sbjct: 80  VAGRVVDQYGKPVPNTLVEM 99


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

1UWY-A nrPDB                                                          652   0.0  
3MN8-A nrPDB                                                          484   e-137
1QMU-A nrPDB                                                          483   e-137
2NSM-A nrPDB                                                          444   e-125
1KWM-A nrPDB                                                          283   1e-76
1ZLI-A nrPDB                                                          282   2e-76
3OSL-A nrPDB                                                          267   1e-71
3D4U-A nrPDB                                                          265   3e-71
4UIB-A nrPDB                                                          260   6e-70
2BOA-A nrPDB                                                          250   1e-66
4BD9-A nrPDB                                                          248   3e-66
3V7Z-A nrPDB                                                          242   2e-64
1AYE-A nrPDB                                                          238   3e-63
1DTD-A nrPDB                                                          237   9e-63
1JQG-A nrPDB                                                          203   2e-52
3K2K-A nrPDB                                                          175   3e-44
4B6Z-A nrPDB                                                          166   2e-41
4A39-A nrPDB                                                          152   2e-37
5AQ0-A nrPDB                                                           90   2e-18

Sequences not found previously or not previously below threshold:

3GLJ-A nrPDB                                                          267   7e-72
1NSA-A nrPDB                                                          261   4e-70
3D68-A nrPDB                                                          235   5e-62
3LMS-A nrPDB                                                          233   1e-61
3KGQ-A nrPDB                                                          223   2e-58
5OM9-A nrPDB                                                          215   5e-56
4UEE-A nrPDB                                                          212   3e-55
1PCA-A nrPDB                                                          211   4e-55
5MRV-A nrPDB                                                          197   7e-51
1CPB-B nrPDB                                                          171   7e-43
2C1C-A nrPDB                                                          165   3e-41
3L2N-A nrPDB                                                          121   6e-28
1CPB-A nrPDB                                                           93   3e-19
2QVP-A nrPDB                                                           51   1e-06
3B2Y-A nrPDB                                                           49   5e-06
5HXD-A nrPDB                                                           47   2e-05
3IEH-A nrPDB                                                           45   6e-05
4OKO-A nrPDB                                                           41   0.001
2QJ8-A nrPDB                                                           37   0.014
4RWR-A nrPDB                                                           36   0.025
4AXV-A nrPDB                                                           36   0.035
2OKL-A nrPDB                                                           34   0.20 
5OCR-A nrPDB                                                           32   0.53 
5JBE-A nrPDB                                                           31   0.79 
5VOC-B nrPDB                                                           31   1.3  
3A22-A nrPDB                                                           30   1.5  
2AZQ-A nrPDB                                                           30   2.7  
3ZHL-A nrPDB                                                           29   3.2  
4E79-A nrPDB                                                           29   5.3  
4M1U-A nrPDB                                                           29   5.5  
2HN1-A nrPDB                                                           29   6.2  
1JQP-A nrPDB                                                           28   9.4  

>1UWY-A nrPDB
          Length = 426

 Score =  652 bits (1683), Expect = 0.0,   Method: Composition-based stats.
 Identities = 426/426 (100%), Positives = 426/426 (100%)

Query: 18  LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77
           LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK
Sbjct: 1   LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 60

Query: 78  YVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPD 137
           YVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPD
Sbjct: 61  YVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPD 120

Query: 138 CYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVAS 197
           CYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVAS
Sbjct: 121 CYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVAS 180

Query: 198 YPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYS 257
           YPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYS
Sbjct: 181 YPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYS 240

Query: 258 WYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKG 317
           WYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKG
Sbjct: 241 WYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKG 300

Query: 318 QVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVI 377
           QVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVI
Sbjct: 301 QVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVI 360

Query: 378 IPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLPDHSAATKPSLFLFLVSL 437
           IPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLPDHSAATKPSLFLFLVSL
Sbjct: 361 IPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLPDHSAATKPSLFLFLVSL 420

Query: 438 LHIFFK 443
           LHIFFK
Sbjct: 421 LHIFFK 426


>3MN8-A nrPDB
          Length = 435

 Score =  484 bits (1245), Expect = e-137,   Method: Composition-based stats.
 Identities = 169/396 (42%), Positives = 246/396 (62%), Gaps = 21/396 (5%)

Query: 21  NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
           +Y  QE +E     + + Y +   +H +G+S++GRNL  L + R  +   +  P  KY+A
Sbjct: 39  HYASQEQLEDLFAGLEKAYPNQAKVHFLGRSLEGRNLLALQISRNTRSRNLLTPPVKYIA 98

Query: 81  NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
           NMHGDETVGR+LL+++  YL+ +  +  ++  L+NST I+++P+MNPDG+   ++ +C  
Sbjct: 99  NMHGDETVGRQLLVYMAQYLLGNHERISDLGQLVNSTDIYLVPTMNPDGYALSQEGNCES 158

Query: 141 ---SIGRENYNQYDLNRNFPDAFEYNNV------SRQPETVAVMKWLKTETFVLSANLHG 191
               +GR N    DLNR+FPD  E ++V      SRQPET A++ W+ ++ FVLSAN HG
Sbjct: 159 LPNYVGRGNAANIDLNRDFPDRLEQSHVHQLRAQSRQPETAALVNWIVSKPFVLSANFHG 218

Query: 192 GALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNG 251
           GA+VASYP+DN + A       SLTPDD VF+ LAHTY+  +P M+KG+ C +  +F  G
Sbjct: 219 GAVVASYPYDNSL-AHNECCEESLTPDDRVFKQLAHTYSDNHPIMRKGNNCND--SFSGG 275

Query: 252 VTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQV 311
           +TNG  WY L GGMQD+NY ++ CFE+T+ELSCCKYP    LP  W  NKASL++ ++Q 
Sbjct: 276 ITNGAHWYELSGGMQDFNYAFSNCFELTIELSCCKYPAASTLPQEWQRNKASLLQLLRQA 335

Query: 312 HLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHD- 370
           H+G+KG V D +G P+ +  V V   +   P RT+K GEY+ LL PG Y ++ +  G+  
Sbjct: 336 HIGIKGLVTDASGFPIADANVYVAGLEEK-PMRTSKRGEYWRLLTPGLYSVHASAFGYQT 394

Query: 371 --PHITKVIIPEKSQNFSALKKDI-LLPFQGQLDSI 403
             P   +V     + N  AL+ D  L P +   D I
Sbjct: 395 SAPQQVRVT----NDNQEALRLDFKLAPVETNFDGI 426


>1QMU-A nrPDB
          Length = 380

 Score =  483 bits (1244), Expect = e-137,   Method: Composition-based stats.
 Identities = 187/371 (50%), Positives = 246/371 (66%), Gaps = 9/371 (2%)

Query: 15  VAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIP 74
           V  +DF +H    ME FL+  A  Y S+T L+S+GKSV+ R L+V+ +   P  H  G P
Sbjct: 3   VQPVDFRHHHFSDMEIFLRRYANEYPSITRLYSVGKSVELRELYVMEISDNPGIHEAGEP 62

Query: 75  EFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVK 134
           EFKY+ NMHG+E VGRELLL+LI+YL  + G DPE+T+L+ STRIHIMPSMNPDG+E  +
Sbjct: 63  EFKYIGNMHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVQSTRIHIMPSMNPDGYEKSQ 122

Query: 135 KPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGAL 194
           + D   ++GR N N YDLNRNFPD F       QPET+AVM WLKT  FVLSANLHGG+L
Sbjct: 123 EGDRGGTVGRNNSNNYDLNRNFPDQFFQVTDPPQPETLAVMSWLKTYPFVLSANLHGGSL 182

Query: 195 VASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKN---KMNFPNG 251
           V +YPFD+  Q   A+YS+S  PDD VFQ LA +Y+  N  M +G  CK+      FP+G
Sbjct: 183 VVNYPFDDDEQGI-AIYSKS--PDDAVFQQLALSYSKENKKMYQGSPCKDLYPTEYFPHG 239

Query: 252 VTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQV 311
           +TNG  WY + GGMQD+NY+   CFE+T+EL C KYP+ E+LP +W  N+ SL+++IKQV
Sbjct: 240 ITNGAQWYNVPGGMQDWNYLNTNCFEVTIELGCVKYPKAEELPKYWEQNRRSLLQFIKQV 299

Query: 312 HLGVKGQVFDQ-NGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHD 370
           H G+ G V D  +G  + N  + V D  H  P  T K G+Y+ LL+ G+Y +  +  G+D
Sbjct: 300 HRGIWGFVLDATDGRGILNATISVADINH--PVTTYKDGDYWRLLVQGTYKVTASARGYD 357

Query: 371 PHITKVIIPEK 381
           P    V +  K
Sbjct: 358 PVTKTVEVDSK 368


>2NSM-A nrPDB
          Length = 439

 Score =  444 bits (1141), Expect = e-125,   Method: Composition-based stats.
 Identities = 169/387 (43%), Positives = 229/387 (59%), Gaps = 30/387 (7%)

Query: 18  LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77
           L F +HR + +   L  V      +T ++SIG+SV+GR+L+VL     P  H    PE K
Sbjct: 2   LAFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVK 61

Query: 78  YVANMHGDETVGRELLLHLIDYLVTSD-GKDPEITNLINSTRIHIMPSMNPDGFE--AVK 134
           YV NMHG+E +GREL+L L ++L      ++  I  LI  TRIHI+PSMNPDG+E  A +
Sbjct: 62  YVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQ 121

Query: 135 KPDC-YYSIGRENYNQYDLNRNFPDAFEY-----------------NNVSRQ--PETVAV 174
            P+   Y +GR N N  DLNRNFPD   Y                 +N   Q  PET AV
Sbjct: 122 GPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLPDNWKSQVEPETRAV 181

Query: 175 MKWLKTETFVLSANLHGGALVASYPFDNGVQ---ATGALYSRSLTPDDDVFQYLAHTYAS 231
           ++W+ +  FVLSANLHGGA+VA+YP+D   +         + + TPDD +FQ LA  Y+ 
Sbjct: 182 IRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLAKVYSY 241

Query: 232 RNPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREE 291
            +  M +G  C +   FP+G+TNG SWY L  GMQD+NY+   CFEITLELSC K+P EE
Sbjct: 242 AHGWMFQGWNCGDY--FPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPPEE 299

Query: 292 KLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEY 351
           +L   W  NK +LI++++QVH G+KG V DQN N L N ++ V    H     +  +G+Y
Sbjct: 300 ELQREWLGNKEALIQFLEQVHQGIKGMVLDQNYNNLANAVISVSGINHD--VTSGDHGDY 357

Query: 352 YLLLLPGSYIINVTVPGHDPHITKVII 378
           + LLLPG Y ++ T PG+DP    V +
Sbjct: 358 FRLLLPGIYTVSATAPGYDPETVTVTV 384


>1KWM-A nrPDB
          Length = 402

 Score =  283 bits (724), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 57/283 (20%), Positives = 107/283 (37%), Gaps = 42/283 (14%)

Query: 21  NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
            Y++ E +EA+ + VA    ++     IG + +GR +++L VG+  +      P      
Sbjct: 103 KYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNK----PAIFMDC 158

Query: 81  NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
             H  E +        +   V + G++ ++T L+N    +++P +N DG+        ++
Sbjct: 159 GFHAREWISPAFCQWFVREAVRTYGREIQVTELLNKLDFYVLPVLNIDGYIYTWTKSRFW 218

Query: 141 SIGRENYN-----QYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTE 181
              R  +        D NRNF   +     SR P              ET A+  +++ +
Sbjct: 219 RKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNK 278

Query: 182 TFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKG 239
              + A   +H  + +  YP+          Y+  L  ++     LA        ++   
Sbjct: 279 LSSIKAYLTIHSYSQMMIYPYS---------YAYKLGENNAELNALAKATVKELASLH-- 327

Query: 240 DECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
                K  +  G T   + YP  GG  D+ Y     +  T EL
Sbjct: 328 ---GTKYTYGPGAT---TIYPAAGGSDDWAYDQGIRYSFTFEL 364


>1ZLI-A nrPDB
          Length = 309

 Score =  282 bits (722), Expect = 2e-76,   Method: Composition-based stats.
 Identities = 57/283 (20%), Positives = 106/283 (37%), Gaps = 42/283 (14%)

Query: 21  NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
            Y+  E +EA+ + VA    ++     IG + +GR +++L VG+  +      P      
Sbjct: 10  KYNNWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNK----PAIFMDC 65

Query: 81  NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
             H  E +        +   V + G++ ++T L+N    +++P +N DG+        ++
Sbjct: 66  GFHAREWISPAFCQWFVREAVRTYGREIQVTELLNKLDFYVLPVLNIDGYIYTWTKSRFW 125

Query: 141 SIGRENYN-----QYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTE 181
              R  +        D NRNF   +     SR P              ET A+  +++ +
Sbjct: 126 RKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNK 185

Query: 182 TFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKG 239
              + A   +H  + +  YP+          Y+  L  ++     LA        ++   
Sbjct: 186 LSSIKAYLTIHSYSQMMIYPYS---------YAYKLGENNAELNALAKATVKELASLH-- 234

Query: 240 DECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
                K  +  G T   + YP  GG  D+ Y     +  T EL
Sbjct: 235 ---GTKYTYGPGAT---TIYPAAGGSDDWAYDQGIRYSFTFEL 271


>3GLJ-A nrPDB
          Length = 401

 Score =  267 bits (682), Expect = 7e-72,   Method: Composition-based stats.
 Identities = 55/283 (19%), Positives = 95/283 (33%), Gaps = 42/283 (14%)

Query: 21  NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
            Y+  E +EA+ K V      +    +IG +  G N+++L VG+         P      
Sbjct: 103 KYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKP----GPNKPAIFMDC 158

Query: 81  NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
             H  E +        +   V + G +  +T  +N    +++P +N DG+      +  +
Sbjct: 159 GFHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMW 218

Query: 141 SIGRE-----NYNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTE 181
              R           D NRNF   +     S  P              ET A+  +++  
Sbjct: 219 RKTRSTNAGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNN 278

Query: 182 TFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKG 239
              + A   +H  + +  YP+          Y   L  ++     LA         +   
Sbjct: 279 LSSIKAYLTIHSYSQMILYPYS---------YDYKLPENNAELNNLAKAAVKELATLY-- 327

Query: 240 DECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
                K  +  G T   + YP  GG  D+ Y     +  T EL
Sbjct: 328 ---GTKYTYGPGAT---TIYPAAGGSDDWAYDQGIKYSFTFEL 364


>3OSL-A nrPDB
          Length = 401

 Score =  267 bits (681), Expect = 1e-71,   Method: Composition-based stats.
 Identities = 61/289 (21%), Positives = 108/289 (37%), Gaps = 41/289 (14%)

Query: 16  AALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75
           ++    YH    + ++++ + + Y  +     IG S +   L+VL V +  KE R     
Sbjct: 95  SSYYEQYHSLNEIYSWIEVMTERYPDMVEKIHIGSSYEKYPLYVLKVSK--KEQRAKN-A 151

Query: 76  FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135
                 +H  E +     L  +  +    GK+   TNL+     +IMP +N DG++   K
Sbjct: 152 MWIDCGIHAREWISPAFCLWFVGSVTYYYGKEKMHTNLLKHMDFYIMPVVNVDGYDYTWK 211

Query: 136 PDCYYSIGRENYN-----QYDLNRNF---------------PDAFEYNNVSRQPETVAVM 175
            D  +   R  +        DLNRNF                + +       +PE  AV 
Sbjct: 212 KDRMWRKNRSLHEKNACVGTDLNRNFASKHWCGEGASSSSCSEIYCGTYPESEPEVKAVA 271

Query: 176 KWLKTETFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRN 233
            +L+     + A  ++H  +    +P+          YSRS + D +    +A       
Sbjct: 272 DFLRRNIKHIKAYISMHSYSQKIVFPYS---------YSRSRSKDHEELSLVAREAVFAM 322

Query: 234 PNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
            N+ +       + + +G +   S Y   GG  D+ Y     +  T EL
Sbjct: 323 ENIHRN------IRYTHG-SGSESLYLAPGGSDDWIYDLGIKYSFTFEL 364


>3D4U-A nrPDB
          Length = 309

 Score =  265 bits (676), Expect = 3e-71,   Method: Composition-based stats.
 Identities = 61/289 (21%), Positives = 108/289 (37%), Gaps = 41/289 (14%)

Query: 16  AALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75
           ++    YH    + ++++ + + Y  +     IG S +   L+VL V +  KE R     
Sbjct: 3   SSYYEQYHSLNEIYSWIEVMTERYPDMVEKIHIGSSYEKYPLYVLKVSK--KEQRAKN-A 59

Query: 76  FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135
                 +H  E +     L  +  +    GK+   TNL+     +IMP +N DG++   K
Sbjct: 60  MWIDCGIHAREWISPAFCLWFVGSVTYYYGKEKMHTNLLKHMDFYIMPVVNVDGYDYTWK 119

Query: 136 PDCYYSIGRENYN-----QYDLNRNF---------------PDAFEYNNVSRQPETVAVM 175
            D  +   R  +        DLNRNF                + +       +PE  AV 
Sbjct: 120 KDRMWRKNRSLHEKNACVGTDLNRNFASKHWCGEGASSSSCSEIYCGTYPESEPEVKAVA 179

Query: 176 KWLKTETFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRN 233
            +L+     + A  ++H  +    +P+          YSRS + D +    +A       
Sbjct: 180 DFLRRNIKHIKAYISMHSYSQKIVFPYS---------YSRSRSKDHEELSLVAREAVFAM 230

Query: 234 PNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
            N+ +       + + +G +   S Y   GG  D+ Y     +  T EL
Sbjct: 231 ENIHRN------IRYTHG-SGSESLYLAPGGSDDWIYDLGIKYSFTFEL 272


>1NSA-A nrPDB
          Length = 395

 Score =  261 bits (667), Expect = 4e-70,   Method: Composition-based stats.
 Identities = 53/283 (18%), Positives = 98/283 (34%), Gaps = 42/283 (14%)

Query: 21  NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
            Y+  E +EA+ + V      +    +IG +  G N+++L VG+         P      
Sbjct: 97  KYNNWETIEAWTEQVTSKNPDLISRSAIGTTFDGDNIYLLKVGKPGSNK----PAIFMDC 152

Query: 81  NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
             H  E + +      +   V + G +  +T  +++   +++P +N DG+      +  +
Sbjct: 153 GFHAREWISQAFCQWFVRDAVRTYGYEAHMTEFLDNLDFYVLPVLNIDGYIYTWTKNRMW 212

Query: 141 SIGREN-----YNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTE 181
              R           D NRNF   +     S  P              ET A+  +++  
Sbjct: 213 RKTRSTNAGSSCTGTDPNRNFNAGWCTVGASVNPCNETYCGSAAESEKETKALADFIRNN 272

Query: 182 TFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKG 239
              + A   +H  + +  YP+          Y   L  +D     LA        ++   
Sbjct: 273 LSSIKAYLTIHSYSQMILYPYS---------YDYKLPENDAELNSLAKGAVKELASLY-- 321

Query: 240 DECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
                  ++  G T   + YP  GG  D+ Y     +  T EL
Sbjct: 322 ---GTSYSYGPGST---TIYPAAGGSDDWAYNQGIKYSFTFEL 358


>4UIB-A nrPDB
          Length = 307

 Score =  260 bits (665), Expect = 6e-70,   Method: Composition-based stats.
 Identities = 54/283 (19%), Positives = 95/283 (33%), Gaps = 42/283 (14%)

Query: 21  NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
            Y+  E +EA+ K V      +    +IG +  G N+++L VG+         P      
Sbjct: 8   KYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKP----GPNKPAIFMDC 63

Query: 81  NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
            +H  E +        +   V + G +  +T  +N    +++P +N DG+      +  +
Sbjct: 64  GIHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMW 123

Query: 141 SIGRE-----NYNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTE 181
              R           D NRNF   +     S  P              ET A+  +++  
Sbjct: 124 RKTRSTNAGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNN 183

Query: 182 TFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKG 239
              + A  ++H  +    YP+          Y   L  ++     LA         +   
Sbjct: 184 LSSIKAYLSIHSYSQHIVYPYS---------YDYKLPENNAELNNLAKAAVKELATLY-- 232

Query: 240 DECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
                K  +  G T   + Y   GG  D+ Y     +  T EL
Sbjct: 233 ---GTKYTYGPGAT---TLYLAPGGGDDWAYDQGIKYSFTFEL 269


>2BOA-A nrPDB
          Length = 404

 Score =  250 bits (637), Expect = 1e-66,   Method: Composition-based stats.
 Identities = 58/287 (20%), Positives = 104/287 (36%), Gaps = 43/287 (14%)

Query: 19  DFNYHRQEGMEAF---LKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75
           +FNY     +EA    +  +A ++  +     IG S + R ++VL          +  P 
Sbjct: 100 NFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFST---GKGVRRPA 156

Query: 76  FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135
               A +H  E + +   +     +V+   +DP IT+++    I ++P  NPDG+   + 
Sbjct: 157 VWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQT 216

Query: 136 PDCYYSIGR-----ENYNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMK 176
            +  +   R      +    D NRN+  +F     S  P              E  +V+ 
Sbjct: 217 QNRLWRKTRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVD 276

Query: 177 WLKTET-FVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPN 235
           +++    F    +LH  + +  YP+          YS    PD +    +A   A    +
Sbjct: 277 FIQKHGNFKGFIDLHSYSQLLMYPYG---------YSVKKAPDAEELDKVARLAAKALAS 327

Query: 236 MKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
           +        +       T   + YP  G   D+ Y     F  T EL
Sbjct: 328 V-----SGTEYQVGPTCT---TVYPASGSSIDWAYDNGIKFAFTFEL 366


>4BD9-A nrPDB
          Length = 310

 Score =  248 bits (633), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 58/287 (20%), Positives = 104/287 (36%), Gaps = 43/287 (14%)

Query: 19  DFNYHRQEGMEAF---LKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75
           +FNY     +EA    +  +A ++  +     IG S + R ++VL          +  P 
Sbjct: 6   NFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFST---GKGVRRPA 62

Query: 76  FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135
               A +H  E + +   +     +V+   +DP IT+++    I ++P  NPDG+   + 
Sbjct: 63  VWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQT 122

Query: 136 PDCYYSIGR-----ENYNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMK 176
            +  +   R      +    D NRN+  +F     S  P              E  +V+ 
Sbjct: 123 QNRLWRKTRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVD 182

Query: 177 WLKTET-FVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPN 235
           +++    F    +LH  + +  YP+          YS    PD +    +A   A    +
Sbjct: 183 FIQKHGNFKGFIDLHSYSQLLMYPYG---------YSVKKAPDAEELDKVARLAAKALAS 233

Query: 236 MKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
           +        +       T   + YP  G   D+ Y     F  T EL
Sbjct: 234 V-----SGTEYQVGPTCT---TVYPASGSSIDWAYDNGIKFAFTFEL 272


>3V7Z-A nrPDB
          Length = 326

 Score =  242 bits (618), Expect = 2e-64,   Method: Composition-based stats.
 Identities = 78/327 (23%), Positives = 129/327 (39%), Gaps = 50/327 (15%)

Query: 17  ALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEF 76
           + D  YH    M   + TVA NY ++    SIGKS +GR LW + +           PE 
Sbjct: 4   SYDSGYHNYNEMVNKINTVASNYPNIVKKFSIGKSYEGRELWAVKISDNVGTDE-NEPEV 62

Query: 77  KYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKP 136
            Y A  H  E +  E+ L+ +D    +   D  ITNL+N+  I+I+ ++NPDG E     
Sbjct: 63  LYTALHHAREHLTVEMALYTLDLFTQNYNLDSRITNLVNNREIYIVFNINPDGGEYDISS 122

Query: 137 DCY--YSIGR-----ENYNQYDLNRNF---------------PDAFEYNNVSRQPETVAV 174
             Y  +   R      +Y   DLNRN+                + +   +    PET A+
Sbjct: 123 GSYKSWRKNRQPNSGSSYVGTDLNRNYGYKWGCCGGSSGSPSSETYRGRSAFSAPETAAM 182

Query: 175 MKWLKTETFVLSANLHGGALVASYPFDNGV-QATGALYS---RSLTPDD-DVFQYLAHTY 229
             ++ +   V+        L+  + +   +    G  Y+     +T DD +VF+ +A+T 
Sbjct: 183 RDFINSR--VVGGKQQIKTLITFHTYSELILYPYGYTYTDVPSDMTQDDFNVFKTMANTM 240

Query: 230 ASRNPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCK--- 286
           A  N    +                    Y   G M D+ Y   + F  T E+       
Sbjct: 241 AQTNGYTPQ---------------QASDLYITDGDMTDWAYGQHKIFAFTFEMYPTSYNP 285

Query: 287 --YPREEKLPSFWNNNKASLIEYIKQV 311
             YP +E +    + NK +++   ++ 
Sbjct: 286 GFYPPDEVIGRETSRNKEAVLYVAEKA 312


>1AYE-A nrPDB
          Length = 401

 Score =  238 bits (608), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 63/314 (20%), Positives = 110/314 (35%), Gaps = 51/314 (16%)

Query: 18  LDFN-YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEF 76
            +F  YH  E +   +  +   +  +    +IG S + R + VL             P  
Sbjct: 100 FNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD-----KPAI 154

Query: 77  KYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKP 136
              A +H  E V +   L   + +V+  GKDP IT+++++  I ++P  NPDG+   +  
Sbjct: 155 WLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTK 214

Query: 137 DCYYSIGREN-----YNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKW 177
           +  +   R           D NRN+   F     S  P              E  +++ +
Sbjct: 215 NRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDF 274

Query: 178 LKTETFV-LSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNM 236
           +K+   V     LH  + +  +P+          Y  +   D D    +A   A    ++
Sbjct: 275 IKSHGKVKAFIILHSYSQLLMFPYG---------YKCTKLDDFDELSEVAQKAAQSLRSL 325

Query: 237 KKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCC-KY----PREE 291
                   K       +     Y   GG  D++Y +   +    EL    +Y    P  +
Sbjct: 326 H-----GTKYKVGPICS---VIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQ 377

Query: 292 KLP---SFWNNNKA 302
            LP     W   KA
Sbjct: 378 ILPTAEETWLGLKA 391


>1DTD-A nrPDB
          Length = 303

 Score =  237 bits (604), Expect = 9e-63,   Method: Composition-based stats.
 Identities = 63/315 (20%), Positives = 109/315 (34%), Gaps = 52/315 (16%)

Query: 18  LDFN-YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEF 76
            +F  YH  E +   +  +   +  +    +IG S + R + VL             P  
Sbjct: 1   FNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD-----KPAI 55

Query: 77  KYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKP 136
              A +H  E V +   L   + +V+  GKDP IT+++++  I ++P  NPDG+   +  
Sbjct: 56  WLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTK 115

Query: 137 DCYYSIGREN------YNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMK 176
           +  +   R            D NRN+   F     S  P              E  +++ 
Sbjct: 116 NRMWRKTRSKVSAGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVD 175

Query: 177 WLKTETFV-LSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPN 235
           ++K+   V     LH  + +  +P+          Y  +   D D    +A   A     
Sbjct: 176 FIKSHGKVKAFIILHSYSQLLMFPYG---------YKCTKLDDFDELSEVAQKAAQSLSR 226

Query: 236 MKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCC-KY----PRE 290
           +        K       +     Y   GG  D++Y +   +    EL    +Y    P  
Sbjct: 227 LH-----GTKYKVGPICS---VIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPAR 278

Query: 291 EKLP---SFWNNNKA 302
           + LP     W   KA
Sbjct: 279 QILPTAEETWLGLKA 293


>3D68-A nrPDB
          Length = 424

 Score =  235 bits (598), Expect = 5e-62,   Method: Composition-based stats.
 Identities = 55/289 (19%), Positives = 104/289 (35%), Gaps = 41/289 (14%)

Query: 16  AALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75
           A+    YH    + ++++ + + +  +     IG S +   L+VL V     + +     
Sbjct: 118 ASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVS---GKEQTAKNA 174

Query: 76  FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135
                 +H  E +     L  I ++    G   + TNL+     ++MP +N DG++   K
Sbjct: 175 IWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWK 234

Query: 136 PDCYYSIGRENYN-----QYDLNRNF---------------PDAFEYNNVSRQPETVAVM 175
            +  +   R  Y        DLNRNF                + +       +PE  AV 
Sbjct: 235 KNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVA 294

Query: 176 KWLKTETFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRN 233
            +L+     + A  ++H  +    +P+          Y+RS + D +    +A       
Sbjct: 295 SFLRRNINQIKAYISMHSYSQHIVFPYS---------YTRSKSKDHEELSLVASEAVRAI 345

Query: 234 PNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
             + K       + +  G     + Y   GG  D+ Y     +  T+EL
Sbjct: 346 EKISKN------IRYTYG-QGSETLYLAPGGGDDWIYDLGIKYSFTIEL 387


>3LMS-A nrPDB
          Length = 309

 Score =  233 bits (594), Expect = 1e-61,   Method: Composition-based stats.
 Identities = 55/289 (19%), Positives = 103/289 (35%), Gaps = 41/289 (14%)

Query: 16  AALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75
           A+    YH    + ++++ + + +  +     IG S +   L+VL V     + +     
Sbjct: 3   ASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVS---GKEQAAKNA 59

Query: 76  FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135
                 +H  E +     L  I ++    G   + TNL+     ++MP +N DG++   K
Sbjct: 60  IWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWK 119

Query: 136 PDCYYSIGRENYN-----QYDLNRNF---------------PDAFEYNNVSRQPETVAVM 175
            +  +   R  Y        DLNRNF                + +       +PE  AV 
Sbjct: 120 KNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVA 179

Query: 176 KWLKTETFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRN 233
            +L+     + A  ++H  +    +P+          Y+RS + D +    +A       
Sbjct: 180 SFLRRNINQIKAYISMHSYSQHIVFPYS---------YTRSKSKDHEELSLVASEAVRAI 230

Query: 234 PNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
               K         + +G     + Y   GG  D+ Y     +  T+EL
Sbjct: 231 EKTSKNT------RYTHGH-GSETLYLAPGGGDDWIYDLGIKYSFTIEL 272


>3KGQ-A nrPDB
          Length = 309

 Score =  223 bits (567), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 51/281 (18%), Positives = 95/281 (33%), Gaps = 41/281 (14%)

Query: 22  YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
           YH  + +  F+  +   +  +     IG+S +GR ++VL             P       
Sbjct: 12  YHTLDEIYDFMDLLVAEHPQLVSKLQIGRSYEGRPIYVLKFSTGGSNR----PAIWIDLG 67

Query: 82  MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
           +H  E + +   +          G+DP  T +++S  I +    NPDGF      +  + 
Sbjct: 68  IHSREWITQATGVWFAKKFTEDYGQDPSFTAILDSMDIFLEIVTNPDGFAFTHSQNRLWR 127

Query: 142 IGR-----ENYNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTET 182
             R           D NRN+   F     S  P              E  +++ ++K   
Sbjct: 128 KTRSVTSSSLCVGVDANRNWDAGFGKAGASSSPCSETYHGKYANSEVEVKSIVDFVKDHG 187

Query: 183 -FVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDE 241
            F    ++H  + +  YP+          Y+    PD      +A +      ++     
Sbjct: 188 NFKAFLSIHSYSQLLLYPYG---------YTTQSIPDKTELNQVAKSAVEALKSLY---- 234

Query: 242 CKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
                 + + +T   + Y   GG  D++Y     +  T EL
Sbjct: 235 -GTSYKYGSIIT---TIYQASGGSIDWSYNQGIKYSFTFEL 271


>5OM9-A nrPDB
          Length = 419

 Score =  215 bits (546), Expect = 5e-56,   Method: Composition-based stats.
 Identities = 51/281 (18%), Positives = 94/281 (33%), Gaps = 41/281 (14%)

Query: 22  YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
           YH  E +  FL  +      +     IG + +GR ++VL             P       
Sbjct: 122 YHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTG----GSKRPAIWIDTG 177

Query: 82  MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
           +H  E V +   +     +    G+D   T ++++  I +    NPDGF      +  + 
Sbjct: 178 IHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWR 237

Query: 142 IGREN-----YNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTET 182
             R +         D NRN+   F  +  S  P              E  +++ ++K   
Sbjct: 238 KTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHG 297

Query: 183 FV-LSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDE 241
            +    ++H  + +  YP+          Y     PD D    L+    +   ++     
Sbjct: 298 NIKAFISIHSYSQLLMYPYG---------YKTEPVPDQDELDQLSKAAVTALASLY---- 344

Query: 242 CKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
              K N+ + +    + Y   G   D+ Y     +  T EL
Sbjct: 345 -GTKFNYGSII---KAIYQASGSTIDWTYSQGIKYSFTFEL 381


>4UEE-A nrPDB
          Length = 309

 Score =  212 bits (539), Expect = 3e-55,   Method: Composition-based stats.
 Identities = 51/281 (18%), Positives = 94/281 (33%), Gaps = 41/281 (14%)

Query: 22  YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
           YH  E +  FL  +      +     IG + +GR ++VL             P       
Sbjct: 12  YHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTG----GSKRPAIWIDTG 67

Query: 82  MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
           +H  E V +   +     +    G+D   T ++++  I +    NPDGF      +  + 
Sbjct: 68  IHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWR 127

Query: 142 IGREN-----YNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTET 182
             R +         D NRN+   F  +  S  P              E  +++ ++K   
Sbjct: 128 KTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHG 187

Query: 183 FV-LSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDE 241
            +    ++H  + +  YP+          Y     PD D    L+    +   ++     
Sbjct: 188 NIKAFISIHSYSQLLMYPYG---------YKTEPVPDQDELDQLSKAAVTALASLY---- 234

Query: 242 CKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
              K N+ + +    + Y   G   D+ Y     +  T EL
Sbjct: 235 -GTKFNYGSII---KAIYQASGSTIDWTYSQGIKYSFTFEL 271


>1PCA-A nrPDB
          Length = 403

 Score =  211 bits (538), Expect = 4e-55,   Method: Composition-based stats.
 Identities = 46/281 (16%), Positives = 96/281 (34%), Gaps = 41/281 (14%)

Query: 22  YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
           YH  E +  F+  +   + ++     IG+S +GR ++VL             P     + 
Sbjct: 107 YHTLEEIYDFMDILVAEHPALVSKLQIGRSYEGRPIYVLKFSTGGSNR----PAIWIDSG 162

Query: 82  MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
           +H  E + +   +     +  + G++   T +++S  I +    NP+GF      +  + 
Sbjct: 163 IHSREWITQASGVWFAKKITENYGQNSSFTAILDSMDIFLEIVTNPNGFAFTHSDNRLWR 222

Query: 142 IGRENYN-----QYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTET 182
             R   +       D NRN+   F     S  P              E  ++  ++K   
Sbjct: 223 KTRSKASGSLCVGSDSNRNWDAGFGGAGASSSPCAETYHGKYPNSEVEVKSITDFVKNNG 282

Query: 183 FV-LSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDE 241
            +    ++H  + +  YP+          Y      D      +A +  +   ++     
Sbjct: 283 NIKAFISIHSYSQLLLYPYG---------YKTQSPADKSELNQIAKSAVAALKSLY---- 329

Query: 242 CKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
                 + + +T     Y   GG+ D+ Y     +  + EL
Sbjct: 330 -GTSYKYGSIIT---VIYQASGGVIDWTYNQGIKYSFSFEL 366


>1JQG-A nrPDB
          Length = 433

 Score =  203 bits (515), Expect = 2e-52,   Method: Composition-based stats.
 Identities = 66/283 (23%), Positives = 103/283 (36%), Gaps = 44/283 (15%)

Query: 23  HRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANM 82
           H  E ++A+L+ +A+ + +V  +   GKS +GR++  L +           P     + +
Sbjct: 122 HSYEEVDAYLQELAKEFPNVVTVVEGGKSFEGRSIKYLRIST-TNFQDASKPVVMMQSLL 180

Query: 83  HGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSI 142
           H  E V     L+ I  LV     D   ++LIN+    I+P  NPDG+      D Y+  
Sbjct: 181 HCREWVTLPATLYAIHKLVI----DVTESDLINNIDWIILPVANPDGYVHTFGGDRYWRK 236

Query: 143 GRENYN-------QYDLNRNF-------------PDAFEYNNVSRQPETVAVMKWL--KT 180
            R             DLNRNF              D F   +   +PE+  +   +    
Sbjct: 237 NRATGYMAGNLCMGVDLNRNFGMNWGTASSSSVCSDTFHGRSAFSEPESSVIRDIIAEHR 296

Query: 181 ETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD 240
               L  ++H    +  Y + NGV  + AL              +    A     +K   
Sbjct: 297 NRMALYLDIHSFGSMILYGYGNGVLPSNAL----------QLHLIGVQMAQAIDRVKWSS 346

Query: 241 ECKNKMNFPNGVTNGYS-WYPLQGGMQDYNYIWAQCFEITLEL 282
             K+ +     V N +   Y   GG  DY    A  F  T EL
Sbjct: 347 N-KDYI-----VGNIFHVLYAASGGASDYAMQAAAPFSYTYEL 383


>5MRV-A nrPDB
          Length = 355

 Score =  197 bits (501), Expect = 7e-51,   Method: Composition-based stats.
 Identities = 43/290 (14%), Positives = 97/290 (33%), Gaps = 42/290 (14%)

Query: 15  VAALDFN-YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGI 73
           +    +N YH    +  +++ +++ Y  V   H +G + +   ++ L + +         
Sbjct: 48  LETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPIYYLKISQPSGN---PK 104

Query: 74  PEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAV 133
                   +H  E +        +  ++ +   +  I  L+ +   +++P +N DG+   
Sbjct: 105 KIIWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSRIRKLLRNLDFYVLPVLNIDGYIYT 164

Query: 134 KKPDCYYSIGRENYN-----QYDLNRNFPDAFEYNNVSRQ--------------PETVAV 174
              D  +   R  +N       DLNRNF  ++     SR               PET AV
Sbjct: 165 WTTDRLWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAV 224

Query: 175 MKWLKTETFVL--SANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASR 232
             +++++   +     +H    +   P+          Y+++ + +      +    A+ 
Sbjct: 225 ASFIESKKDDILCFLTMHSYGQLILTPYG---------YTKNKSSNHPEMIQVGQKAANA 275

Query: 233 NPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
                               ++    Y   G  +D+       F  T EL
Sbjct: 276 LKAKY-----GTNYRVG---SSADILYASSGSSRDWARDIGIPFSYTFEL 317


>3K2K-A nrPDB
          Length = 403

 Score =  175 bits (443), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 57/293 (19%), Positives = 107/293 (36%), Gaps = 42/293 (14%)

Query: 20  FNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79
           F  + +E    FL  V Q       +  +G++V+GR + ++V+G  P E      +   +
Sbjct: 130 FEPYSEERHSEFLGAVQQM--PQASVVELGRTVEGRPMSLVVLGT-PDEAGAAKKKVWII 186

Query: 80  ANMHGDETVGRELLLHLIDYLVTSD--GKDPEITNLINSTRIHIMPSMNPDGFEAVKKPD 137
           A  H  E++    +  L+  LV       DP    L +    +I+P+MNPDG        
Sbjct: 187 ARQHPGESMAEWFIEGLVKRLVGWGDWSGDPVARKLYDHATFYIVPNMNPDG-------- 238

Query: 138 CYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVAS 197
             +   R N    +LNR +       +  R PE + V   +      L  ++HG      
Sbjct: 239 SVHGNLRTNAAGANLNREW----MEPDAERSPEVLVVRDAIHAIGCDLFFDIHG------ 288

Query: 198 YPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYS 257
               +            + P     Q +  + A  +   +   + +++  +P G     +
Sbjct: 289 ----DEDLPYVFAAGSEMLPGFTEQQRVEQS-AFIDSFKRASPDFQDEHGYPPGKYREDA 343

Query: 258 WYPLQGGMQDYNYIWAQ--CFEITLELSCCKYPREEKLPSF---WNNNKASLI 305
           +           YI  +  C  +TLE+    +     LP     WN  +++ +
Sbjct: 344 FKLASK------YIGHRFGCLSLTLEM---PFKDNANLPDEHIGWNGARSASL 387


>1CPB-B nrPDB
          Length = 217

 Score =  171 bits (432), Expect = 7e-43,   Method: Composition-based stats.
 Identities = 36/197 (18%), Positives = 67/197 (34%), Gaps = 38/197 (19%)

Query: 107 DPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGREN-----YNQYDLNRNFPDAFE 161
           +  +T  ++    +++P +N DG+      +  +   R           DLNRNF   + 
Sbjct: 1   EIHMTEFLDKLDFYVLPVVNIDGYIYTWTTNRMWRKTRSTRAGSSCTGTDLNRNFDAGWC 60

Query: 162 YNNVSRQP--------------ETVAVMKWLKTETFVLSA--NLHGGALVASYPFDNGVQ 205
               S  P              E+ AV  +++     + A   +H  + +  YP+     
Sbjct: 61  SIGASNNPCSETYCGSAAESEKESKAVADFIRNHLSSIKAYLTIHSYSQMMLYPYS---- 116

Query: 206 ATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGM 265
                Y   L  ++     LA     +  ++          ++  G T   + YP  GG 
Sbjct: 117 -----YDYKLPKNNVELNTLAKGAVKKLASLH-----GTTYSYGPGAT---TIYPASGGS 163

Query: 266 QDYNYIWAQCFEITLEL 282
            D+ Y     +  T EL
Sbjct: 164 DDWAYDQGIKYSFTFEL 180


>4B6Z-A nrPDB
          Length = 405

 Score =  166 bits (420), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 42/174 (24%), Positives = 71/174 (40%), Gaps = 17/174 (9%)

Query: 20  FNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79
           F  + +E   AFL  V Q       +  +G++V+GR + +L +G  P+       +   +
Sbjct: 132 FEPYSEERHAAFLGAVQQL--PQASVVELGRTVEGRPMSLLTLGT-PETDGAPKKKVWII 188

Query: 80  ANMHGDETVGRELLLHLIDYLVTSD--GKDPEITNLINSTRIHIMPSMNPDGFEAVKKPD 137
           A  H  E++    +  L+  L        DP    L +    HI+P+MNPDG        
Sbjct: 189 ARQHPGESMAEWFVEGLVKRLAGWGDWAGDPVARKLYDRVTFHIVPNMNPDG-------- 240

Query: 138 CYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHG 191
             +   R N    +LNR +       +  R PE +AV   +      +  ++HG
Sbjct: 241 SVHGNLRTNAAGANLNREWMA----PDAERSPEVLAVRDAIHAIGCDMFFDIHG 290


>2C1C-A nrPDB
          Length = 312

 Score =  165 bits (418), Expect = 3e-41,   Method: Composition-based stats.
 Identities = 54/290 (18%), Positives = 97/290 (33%), Gaps = 43/290 (14%)

Query: 17  ALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEF 76
             D NY   E ++ +L  + + Y  V  + +  +S +GR +  + +     E     P  
Sbjct: 2   PYD-NYQELEVIDEYLDYIGEKYPDVATVVNAAESFEGRPIKYIKISTTNFEDE-NKPVI 59

Query: 77  KYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKP 136
                +H  E +    +   I  LV     D    +L+      ++P +NPDG++     
Sbjct: 60  FIDGGIHAREWISPPSVTWAIHKLVE----DVTENDLLEKFDWILLPVVNPDGYKYTFTN 115

Query: 137 DCYYSIGRENYN--------QYDLNRNFP--------------DAFEYNNVSRQPETVAV 174
           + ++   R   N          D NRNF               D +   +   + ET  V
Sbjct: 116 ERFWRKTRSTNNNPLSQICRGADGNRNFDFVWNSIGTSNSPCSDIYAGTSAFSEVETRVV 175

Query: 175 MKWLKTE--TFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASR 232
              L        L   +H    +  YP+ +     G+L   +L           HT    
Sbjct: 176 RDILHEHLARMALYLTMHSFGSMILYPWGHD----GSLSQNALG---------LHTVGVA 222

Query: 233 NPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
             ++ + +   N   +  G +     Y + G  +DY +        T EL
Sbjct: 223 MASVIQSNALPNFPPYTVGNSALVIGYYIAGSSEDYAHSIGVPLSYTYEL 272


>4A39-A nrPDB
          Length = 388

 Score =  152 bits (385), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 43/172 (25%), Positives = 73/172 (42%), Gaps = 20/172 (11%)

Query: 20  FNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79
           F  + +E     ++             ++G SV+GR++ +L V R P  H     +   +
Sbjct: 123 FEPYSRERHARLVERALGIEG--VERLAVGTSVQGRDIELLRVRRHPDSHL----KLWVI 176

Query: 80  ANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCY 139
           A  H  E +    +  LI+ L   D  D E+  L+    ++++P+MNPDG         +
Sbjct: 177 AQQHPGEHMAEWFMEGLIERLQRPD--DTEMQRLLEKADLYLVPNMNPDG--------AF 226

Query: 140 YSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHG 191
           +   R N    DLNR    A+   +  R PE   V + +K     L  ++HG
Sbjct: 227 HGNLRTNAAGQDLNR----AWLEPSAERSPEVWFVQQEMKRHGVDLFLDIHG 274


>3L2N-A nrPDB
          Length = 395

 Score =  121 bits (303), Expect = 6e-28,   Method: Composition-based stats.
 Identities = 37/177 (20%), Positives = 69/177 (38%), Gaps = 20/177 (11%)

Query: 15  VAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIP 74
           +    F  +  E     +  V   +  +     +G ++ GR++ ++ VG           
Sbjct: 123 IQIAYFTPYSYERHLDLISAVQ-LHP-LVSTEHLGLTLDGRDMTLVKVGD----DDPSKK 176

Query: 75  EFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVK 134
                A  H  ET+   L+  L++ L+ +D   P    L++    +I+P+MNPDG     
Sbjct: 177 SIWITARQHPGETMAEWLVEGLLNQLLDNDC--PTSKALLDKANFYIVPNMNPDG----- 229

Query: 135 KPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHG 191
                    R N    +LNR +    +  ++ R PE   V+  +      L  ++HG
Sbjct: 230 ---SVRGHLRTNAVGANLNREW----QTPSLERSPEVYYVVNKMHETGVDLFYDVHG 279


>1CPB-A nrPDB
          Length = 82

 Score = 92.9 bits (229), Expect = 3e-19,   Method: Composition-based stats.
 Identities = 15/79 (18%), Positives = 28/79 (35%), Gaps = 4/79 (5%)

Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
           Y+  E +EA+ + VA     +    +IG +  G  +++L VG+         P      
Sbjct: 8  KYNNWETIEAWTEQVASENPDLISRSAIGTTFLGNTIYLLKVGKPGSNK----PAVFMDC 63

Query: 81 NMHGDETVGRELLLHLIDY 99
            H  E +        +  
Sbjct: 64 GFHAREWISPAFCQWFVRE 82


>5AQ0-A nrPDB
          Length = 82

 Score = 90.2 bits (222), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 4/69 (5%)

Query: 314 GVKGQVFDQ-NGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDP- 371
           GVKG V D   G+ L N  + V    H     T ++G++Y LL+PG+Y + V + G+ P 
Sbjct: 2   GVKGFVKDSITGSGLENATISVAGINH--NITTGRFGDFYRLLVPGTYNLTVVLTGYMPL 59

Query: 372 HITKVIIPE 380
            +T V++ E
Sbjct: 60  TVTNVVVKE 68


>2QVP-A nrPDB
          Length = 275

 Score = 50.9 bits (120), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 28/143 (19%), Positives = 47/143 (32%), Gaps = 28/143 (19%)

Query: 43  THLHSIGKSVKGR----NLWVLVVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLID 98
           T    +G  + G+     L++L         + G+P     A  HG+E+ G   LLH + 
Sbjct: 35  TERLGLGSKILGQAGHHPLYLLQ----SPGQKAGLPNLLISAGFHGEESAGPWGLLHFLS 90

Query: 99  YLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNF-- 156
            L            L     + ++P +NP GF             R N    + NR F  
Sbjct: 91  QLDG---------ELFKRVNLSVLPLVNPTGFAKGH---------RFNELGENPNRGFFI 132

Query: 157 PDAFEYNNVSRQPETVAVMKWLK 179
            +           E   +++   
Sbjct: 133 ENGKAKPGADTSAEGRILLEHAH 155


>3B2Y-A nrPDB
          Length = 275

 Score = 48.6 bits (114), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 46/283 (16%), Positives = 86/283 (30%), Gaps = 37/283 (13%)

Query: 26  EGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANMHGD 85
             ++AF   +A+  + +    +   SV    + +          R  +P     +  HG+
Sbjct: 23  NDIDAFYAQLAEEVNRLGLKKNTLGSVDSFAINLYQ----SASQRSDLPSLLISSGFHGE 78

Query: 86  ETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRE 145
           E  G   +LH +  L            L     + ++P +NP GF+A  + + +      
Sbjct: 79  EAAGPWGMLHFLRGLQ---------PALFERVNLSLLPLVNPTGFKAGHRFNRF------ 123

Query: 146 NYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQ 205
                + NR F              T    K L     +L A    G L      ++ + 
Sbjct: 124 ---GENPNRGFTLENGKPT--PNEHTSLEGKLLLEHAQLLCAASRDGILTC---HEDVLM 175

Query: 206 ATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGM 265
               +YS   T     F               K  +       P  VT+G  +       
Sbjct: 176 NETYVYSFEPTQTPGRFSLGLR---DALGQYFKLAKDGFIDECP--VTDGVIFNHFDTSF 230

Query: 266 QDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYI 308
           + +              +C + P +E        N A++ ++I
Sbjct: 231 EAFLVRSGAKLA-----ACSETPGQEDFDRRVQANSAAMGQFI 268


>5HXD-A nrPDB
          Length = 237

 Score = 47.1 bits (110), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 34/166 (20%), Positives = 51/166 (30%), Gaps = 49/166 (29%)

Query: 47  SIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGK 106
             G+S+ G  L         +E  +       +A  HGDE      L   +  L  S  +
Sbjct: 19  HYGRSLLGAPLIWFPAPAASRESGL------ILAGTHGDENSSVVTLSCALRTLTPSLRR 72

Query: 107 DPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDA------- 159
                        H++  +NPDG +            R N N  DLNRNFP A       
Sbjct: 73  H------------HVVLCVNPDGCQLG---------LRANANGVDLNRNFPAANWKEGET 111

Query: 160 ---------------FEYNNVSRQPETVAVMKWLKTETFVLSANLH 190
                             +    +PET A+ + +         + H
Sbjct: 112 VYRWNSAAEERDVVLLTGDKPGSEPETQALCQLIHRIQPAWVVSFH 157


>3IEH-A nrPDB
          Length = 276

 Score = 45.1 bits (105), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 21/87 (24%), Positives = 33/87 (37%), Gaps = 18/87 (20%)

Query: 70  RIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDG 129
           + G+P     A  HG+E+ G   LLH +              +L     + ++P +NP G
Sbjct: 63  KSGLPSLLISAGFHGEESAGPWGLLHFLSEAS---------ADLFERVNLSLLPLVNPTG 113

Query: 130 FEAVKKPDCYYSIGRENYNQYDLNRNF 156
           F         +   R N    + NR F
Sbjct: 114 F------SRGH---RFNKYGENPNRGF 131


>4OKO-A nrPDB
          Length = 312

 Score = 40.9 bits (94), Expect = 0.001,   Method: Composition-based stats.
 Identities = 34/168 (20%), Positives = 60/168 (35%), Gaps = 31/168 (18%)

Query: 25  QEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANMHG 84
           Q+  E  +  +  ++  +     +   V    L+ L      K      P       +HG
Sbjct: 33  QQEAEKKILALVSDF-DIDEYGQLDYPVGSYKLYALK----TKNWDASKPYVLVTGGVHG 87

Query: 85  DETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGR 144
            ET G +  +           +D           I I+P ++P G+E         +I R
Sbjct: 88  YETSGVQGAISFAQTRALEFARD---------YNIVILPCLSPWGYE---------TINR 129

Query: 145 ENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTET--FVLSANLH 190
            N N  D NR+F   +  +      E V  MK++ +    F++  +LH
Sbjct: 130 WNPNALDPNRSF---YLESGCQ---EAVLAMKYVFSLGVEFLMHIDLH 171


>2QJ8-A nrPDB
          Length = 332

 Score = 37.0 bits (84), Expect = 0.014,   Method: Composition-based stats.
 Identities = 32/166 (19%), Positives = 48/166 (28%), Gaps = 37/166 (22%)

Query: 53  KGRNLWVLVVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITN 112
           KG +   L +  F      G P        HG+E  G      L   LV    +      
Sbjct: 26  KGADCEALSLPVFSCNRGEG-PSLLITGGNHGNELQGPI----LARRLVKWLPEAQRCG- 79

Query: 113 LINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRENYN-QYDLNRNFPDAFEYNNVSRQPET 171
                RI I+P +NP             +  R       +LNR FP   + +   R    
Sbjct: 80  -----RIIIVPEINP---------LAVQAWTRNTPIDGKNLNRVFPGRSDGSVSER---- 121

Query: 172 VAVMKWLKTET---FVLSANLHGGA-------LVASYPFDNGVQAT 207
             +   +            +LH           + S+P  +  Q T
Sbjct: 122 --IADAISRLLLPVVDTVLDLHSFGPTWDCAPSIISHPIADIDQMT 165


>4RWR-A nrPDB
          Length = 331

 Score = 36.3 bits (82), Expect = 0.025,   Method: Composition-based stats.
 Identities = 21/108 (19%), Positives = 35/108 (32%), Gaps = 6/108 (5%)

Query: 287 YPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTN 346
           Y  +E+L   W NN  + ++ I++      GQV    G P+                RT 
Sbjct: 124 YKSKEELKKQWGNNYENNLKKIEEAVSKTAGQVLTYEGKPISASFFSTS------NGRTE 177

Query: 347 KYGEYYLLLLPGSYIINVTVPGHDPHITKVIIPEKSQNFSALKKDILL 394
              +Y+    P    ++       P  T   I   +     L   +L 
Sbjct: 178 NAADYWGNDYPYLKSVDSPWDQASPKFTSEQIFTVADFQKRLGVKVLA 225


>4AXV-A nrPDB
          Length = 243

 Score = 35.9 bits (81), Expect = 0.035,   Method: Composition-based stats.
 Identities = 32/116 (27%), Positives = 37/116 (31%), Gaps = 27/116 (23%)

Query: 42  VTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLV 101
           +    S GKSV G  L             +       +A  HGDET     L   +  L 
Sbjct: 20  LITPTSYGKSVLGAPLLYFPAQVESNSRGL------ILAGTHGDETASIAGLSCALRSLP 73

Query: 102 TSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFP 157
               K   I             SMNPD  +            R N NQ DLNR FP
Sbjct: 74  AECLKHDVIL------------SMNPDANQLG---------TRANANQVDLNRAFP 108


>2OKL-A nrPDB
          Length = 185

 Score = 33.6 bits (75), Expect = 0.20,   Method: Composition-based stats.
 Identities = 15/72 (20%), Positives = 27/72 (37%), Gaps = 7/72 (9%)

Query: 319 VFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVII 378
           V D +G    + +   +   H       + GE       G   ++  VPG+ P  T++ +
Sbjct: 78  VTDADGTLYSHALFNPKIISHSVERTYLQGGE-------GCLSVDREVPGYVPRYTRITV 130

Query: 379 PEKSQNFSALKK 390
              S N   +K 
Sbjct: 131 KATSINGEEVKL 142


>5OCR-A nrPDB
          Length = 286

 Score = 32.0 bits (71), Expect = 0.53,   Method: Composition-based stats.
 Identities = 27/188 (14%), Positives = 55/188 (29%), Gaps = 29/188 (15%)

Query: 4   PCLWLGLLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGR--NLWVLV 61
           P  WL       +  D++    E + + +  V                 +G   +++ + 
Sbjct: 117 PSFWL------YSDFDYSVANGETVYSEIDVVELQQFDW---------YEGHQDDIYDMD 161

Query: 62  VGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHI 121
           +         G         M+  E + +              G +     +I     ++
Sbjct: 162 LNLHAVVKENGQ-GVWKRPKMYPQEQLNKWRAPWDPSKDFHIYGCEVNQNEII----WYV 216

Query: 122 MPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVA-VMKWLKT 180
                 DG E  +KP+ Y+           L + F   F+  N +  PET A   + L  
Sbjct: 217 ------DGVEVARKPNKYWHRPMNVTLSLGLRKPFVKFFDNKNNAINPETDAKAREKLSD 270

Query: 181 ETFVLSAN 188
               +  +
Sbjct: 271 IPTSMYVD 278


>5JBE-A nrPDB
          Length = 854

 Score = 31.3 bits (69), Expect = 0.79,   Method: Composition-based stats.
 Identities = 21/162 (12%), Positives = 48/162 (29%), Gaps = 7/162 (4%)

Query: 124 SMNPDGFEAVKKPDCYYSIGRENYNQYD---LNRNFPDAFEYNNVSRQPETVAVMKWLKT 180
           +++ D    V         G  +Y   +   +NR   +    NN    PE +       +
Sbjct: 160 TIDSDQVIFVNNNSKDPRKGNTSYADSNYRLMNRTINNQAGNNNSDNSPELLVGNDIDNS 219

Query: 181 ETFVLSANLHGGALVASY----PFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNM 236
              V + NL+    + +Y     ++      G     +   D DV   +           
Sbjct: 220 NPVVQAENLNWEYFLLNYGKLMGYNPDGNFDGFRVDAADNIDADVLDQMGQLMNDMYHTK 279

Query: 237 KKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEI 278
                  + +++  G  +G +    + G         + + +
Sbjct: 280 GNPQNANDHLSYNEGYHSGAAQMLNEKGNPQLYMDSGEFYTL 321


>5VOC-B nrPDB
          Length = 278

 Score = 30.9 bits (68), Expect = 1.3,   Method: Composition-based stats.
 Identities = 18/80 (22%), Positives = 25/80 (31%), Gaps = 16/80 (20%)

Query: 6  LWLGLLLPLV--AALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKG-------RN 56
          LW  LLLP+V  AA+       E        V      +T    +G+  +G       R 
Sbjct: 19 LWCCLLLPIVSSAAVSVAPTAAE-------KVPAECPELTRRCLLGEVFEGDKYESWLRP 71

Query: 57 LWVLVVGRFPKEHRIGIPEF 76
          L  +     P    I     
Sbjct: 72 LVNVTGRDGPLSQLIRYRPV 91


>3A22-A nrPDB
          Length = 614

 Score = 30.5 bits (67), Expect = 1.5,   Method: Composition-based stats.
 Identities = 20/123 (16%), Positives = 37/123 (30%), Gaps = 23/123 (18%)

Query: 72  GIPEFKYVAN---MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSM--- 125
           G P    + N    +       +  L      +   G  P +T+L+++    + P+    
Sbjct: 172 GRPLTLSICNWGYQNPWNWAAGQAPLWRTSTDIIYYGNQPSMTSLLSNFDQTLHPTAQHT 231

Query: 126 ----NP-------DGFEAVKKPDCYYSIGRENY---NQYDLNRNFPDAFEYNNVSRQPET 171
               +P       DGF A +                   DL     +      + + PE 
Sbjct: 232 GYYNDPDMLMVGMDGFTAAQNRTHMNLWAISGAPLLAGNDLTTMTSETA---GILKNPEV 288

Query: 172 VAV 174
           +AV
Sbjct: 289 IAV 291


>2AZQ-A nrPDB
          Length = 311

 Score = 29.7 bits (65), Expect = 2.7,   Method: Composition-based stats.
 Identities = 14/36 (38%), Positives = 17/36 (47%), Gaps = 3/36 (8%)

Query: 315 VKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGE 350
           ++GQVFD NG PL    V   D  H     T  Y +
Sbjct: 135 LQGQVFDANGKPLAGATV---DLWHANTQGTYSYFD 167


>3ZHL-A nrPDB
          Length = 127

 Score = 29.3 bits (64), Expect = 3.2,   Method: Composition-based stats.
 Identities = 9/81 (11%), Positives = 24/81 (29%), Gaps = 11/81 (13%)

Query: 230 ASRNPNMKKGDECKNKMNFPNGVTNGYSWY---------PLQGGMQDYNYIWAQ--CFEI 278
           +     +++      +       + G +WY           +   ++  Y+       E 
Sbjct: 31  SYAMGWVRQAPGKGPEWVSLISGSGGSTWYDDSVKGRFTISRDNSKNLLYLQMNSLRAED 90

Query: 279 TLELSCCKYPREEKLPSFWNN 299
           T    C ++    + P +W  
Sbjct: 91  TAVYYCARHAPSTEAPDYWGQ 111


>4E79-A nrPDB
          Length = 357

 Score = 28.6 bits (62), Expect = 5.3,   Method: Composition-based stats.
 Identities = 17/81 (20%), Positives = 31/81 (38%), Gaps = 2/81 (2%)

Query: 299 NNKASLIEYIKQVHLGVKGQVFDQNGNPLPN-VIVEVQDRKHICPYRTNKYGEYYLLLLP 357
            +K       +  HL VKG++  +      N   +E  +  H+      K+ +   +   
Sbjct: 2   GSKVQQYRLDELAHL-VKGELIGEGSLQFSNLASLENAEVNHLTFVNGEKHLDQAKVSRA 60

Query: 358 GSYIINVTVPGHDPHITKVII 378
           G+YI+   +  H P     II
Sbjct: 61  GAYIVTAALKEHLPEKDNFII 81


>4M1U-A nrPDB
          Length = 297

 Score = 28.6 bits (62), Expect = 5.5,   Method: Composition-based stats.
 Identities = 7/56 (12%), Positives = 22/56 (39%)

Query: 327 LPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVIIPEKS 382
           +    + V    +       ++ ++  + +PG   +++T       + +V   E+S
Sbjct: 71  IEQNNLYVAGFVNTATNTFYRFSDFTHISVPGVTTVSMTTDSSYTTLQRVAALERS 126


>2HN1-A nrPDB
          Length = 266

 Score = 28.6 bits (62), Expect = 6.2,   Method: Composition-based stats.
 Identities = 17/109 (15%), Positives = 36/109 (33%), Gaps = 3/109 (2%)

Query: 50  KSVKGRNLWVLVVGRFPKEHRIGIPEFKYV-ANMHGDETVGRELLLHL-IDYLVTSDGKD 107
           KSV+ + L V  +    +       +       +H DE++  ++   L I  L   D  +
Sbjct: 42  KSVEFKELEVGELESVVRSALALNKKLWIDVVGVH-DESLIAKICEFLGIHPLAAEDILN 100

Query: 108 PEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNF 156
                 I     H+   +    +    + D    + ++N       R +
Sbjct: 101 TAQRVKIEDYDDHLFLVLKILLYNETLEIDQLSLVLKKNLVATFEEREY 149


>1JQP-A nrPDB
          Length = 438

 Score = 27.8 bits (60), Expect = 9.4,   Method: Composition-based stats.
 Identities = 12/49 (24%), Positives = 20/49 (40%), Gaps = 1/49 (2%)

Query: 248 FPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSF 296
           +  G   G+ +       QD+  +   CF  T   + CK P+E  L  +
Sbjct: 269 YAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCK-PKENCLRYY 316


  Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
    Posted date:  Jan 3, 2023  9:05 PM
  Number of letters in database: 10,336,785
  Number of sequences in database:  36,641
  
Lambda     K      H
   0.311    0.127    0.346 

Lambda     K      H
   0.267   0.0393    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,579,089
Number of Sequences: 36641
Number of extensions: 702915
Number of successful extensions: 2064
Number of sequences better than 10.0: 53
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 1812
Number of HSP's gapped (non-prelim): 105
length of query: 443
length of database: 10,336,785
effective HSP length: 100
effective length of query: 343
effective length of database: 6,672,685
effective search space: 2288730955
effective search space used: 2288730955
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.4 bits)
S2: 60 (27.8 bits)