BLASTP 2.2.23 [Feb-03-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= P14384
(443 letters)
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
36,641 sequences; 10,336,785 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
1UWY-A nrPDB 888 0.0
1QMU-A nrPDB 365 e-101
3MN8-A nrPDB 323 6e-89
2NSM-A nrPDB 301 5e-82
3V7Z-A nrPDB 72 5e-13
4A39-A nrPDB 54 2e-07
1KWM-A nrPDB 49 4e-06
1ZLI-A nrPDB 49 5e-06
4BD9-A nrPDB 46 4e-05
2BOA-A nrPDB 45 5e-05
3OSL-A nrPDB 45 7e-05
4B6Z-A nrPDB 45 8e-05
3D4U-A nrPDB 44 1e-04
1DTD-A nrPDB 44 1e-04
1JQG-A nrPDB 44 2e-04
3K2K-A nrPDB 44 2e-04
1AYE-A nrPDB 43 2e-04
5AQ0-A nrPDB 41 0.001
4UIB-A nrPDB 40 0.002
3GLJ-A nrPDB 39 0.005
1NSA-A nrPDB 39 0.006
3KGQ-A nrPDB 36 0.027
3L2N-A nrPDB 36 0.032
3D68-A nrPDB 35 0.068
3LMS-A nrPDB 35 0.072
4UEE-A nrPDB 33 0.18
2QVP-A nrPDB 33 0.21
5MRV-A nrPDB 33 0.21
5OM9-A nrPDB 33 0.29
1PCA-A nrPDB 32 0.53
5HXD-A nrPDB 32 0.60
4GFJ-A nrPDB 31 0.86
5HM5-A nrPDB 31 0.97
3IEH-A nrPDB 31 1.0
2C1C-A nrPDB 30 2.2
6D97-A nrPDB 30 2.6
3B2Y-A nrPDB 29 3.2
3N5M-A nrPDB 28 6.5
1SEZ-A nrPDB 28 8.8
1YKN-B nrPDB 28 9.4
>1UWY-A nrPDB
Length = 426
Score = 888 bits (2295), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 426/426 (100%), Positives = 426/426 (100%)
Query: 18 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77
LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK
Sbjct: 1 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 60
Query: 78 YVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPD 137
YVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPD
Sbjct: 61 YVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPD 120
Query: 138 CYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVAS 197
CYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVAS
Sbjct: 121 CYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVAS 180
Query: 198 YPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYS 257
YPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYS
Sbjct: 181 YPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYS 240
Query: 258 WYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKG 317
WYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKG
Sbjct: 241 WYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKG 300
Query: 318 QVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVI 377
QVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVI
Sbjct: 301 QVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVI 360
Query: 378 IPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLPDHSAATKPSLFLFLVSL 437
IPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLPDHSAATKPSLFLFLVSL
Sbjct: 361 IPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLPDHSAATKPSLFLFLVSL 420
Query: 438 LHIFFK 443
LHIFFK
Sbjct: 421 LHIFFK 426
>1QMU-A nrPDB
Length = 380
Score = 365 bits (937), Expect = e-101, Method: Compositional matrix adjust.
Identities = 187/367 (50%), Positives = 247/367 (67%), Gaps = 10/367 (2%)
Query: 15 VAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIP 74
V +DF +H ME FL+ A Y S+T L+S+GKSV+ R L+V+ + P H G P
Sbjct: 3 VQPVDFRHHHFSDMEIFLRRYANEYPSITRLYSVGKSVELRELYVMEISDNPGIHEAGEP 62
Query: 75 EFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVK 134
EFKY+ NMHG+E VGRELLL+LI+YL + G DPE+T+L+ STRIHIMPSMNPDG+E +
Sbjct: 63 EFKYIGNMHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVQSTRIHIMPSMNPDGYEKSQ 122
Query: 135 KPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGAL 194
+ D ++GR N N YDLNRNFPD F QPET+AVM WLKT FVLSANLHGG+L
Sbjct: 123 EGDRGGTVGRNNSNNYDLNRNFPDQFFQVTDPPQPETLAVMSWLKTYPFVLSANLHGGSL 182
Query: 195 VASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKN---KMNFPNG 251
V +YPFD+ Q A+YS+S PDD VFQ LA +Y+ N M +G CK+ FP+G
Sbjct: 183 VVNYPFDDDEQGI-AIYSKS--PDDAVFQQLALSYSKENKKMYQGSPCKDLYPTEYFPHG 239
Query: 252 VTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQV 311
+TNG WY + GGMQD+NY+ CFE+T+EL C KYP+ E+LP +W N+ SL+++IKQV
Sbjct: 240 ITNGAQWYNVPGGMQDWNYLNTNCFEVTIELGCVKYPKAEELPKYWEQNRRSLLQFIKQV 299
Query: 312 HLGVKGQVFDQ-NGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHD 370
H G+ G V D +G + N + V D H P T K G+Y+ LL+ G+Y + + G+D
Sbjct: 300 HRGIWGFVLDATDGRGILNATISVADINH--PVTTYKDGDYWRLLVQGTYKVTASARGYD 357
Query: 371 PHITKVI 377
P +TK +
Sbjct: 358 P-VTKTV 363
>3MN8-A nrPDB
Length = 435
Score = 323 bits (829), Expect = 6e-89, Method: Compositional matrix adjust.
Identities = 169/396 (42%), Positives = 246/396 (62%), Gaps = 21/396 (5%)
Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
+Y QE +E + + Y + +H +G+S++GRNL L + R + + P KY+A
Sbjct: 39 HYASQEQLEDLFAGLEKAYPNQAKVHFLGRSLEGRNLLALQISRNTRSRNLLTPPVKYIA 98
Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
NMHGDETVGR+LL+++ YL+ + + ++ L+NST I+++P+MNPDG+ ++ +C
Sbjct: 99 NMHGDETVGRQLLVYMAQYLLGNHERISDLGQLVNSTDIYLVPTMNPDGYALSQEGNCES 158
Query: 141 ---SIGRENYNQYDLNRNFPDAFEYNNV------SRQPETVAVMKWLKTETFVLSANLHG 191
+GR N DLNR+FPD E ++V SRQPET A++ W+ ++ FVLSAN HG
Sbjct: 159 LPNYVGRGNAANIDLNRDFPDRLEQSHVHQLRAQSRQPETAALVNWIVSKPFVLSANFHG 218
Query: 192 GALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNG 251
GA+VASYP+DN + A SLTPDD VF+ LAHTY+ +P M+KG+ C + +F G
Sbjct: 219 GAVVASYPYDNSL-AHNECCEESLTPDDRVFKQLAHTYSDNHPIMRKGNNCND--SFSGG 275
Query: 252 VTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQV 311
+TNG WY L GGMQD+NY ++ CFE+T+ELSCCKYP LP W NKASL++ ++Q
Sbjct: 276 ITNGAHWYELSGGMQDFNYAFSNCFELTIELSCCKYPAASTLPQEWQRNKASLLQLLRQA 335
Query: 312 HLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHD- 370
H+G+KG V D +G P+ + V V + P RT+K GEY+ LL PG Y ++ + G+
Sbjct: 336 HIGIKGLVTDASGFPIADANVYVAGLEEK-PMRTSKRGEYWRLLTPGLYSVHASAFGYQT 394
Query: 371 --PHITKVIIPEKSQNFSALKKDI-LLPFQGQLDSI 403
P +V + N AL+ D L P + D I
Sbjct: 395 SAPQQVRVT----NDNQEALRLDFKLAPVETNFDGI 426
>2NSM-A nrPDB
Length = 439
Score = 301 bits (770), Expect = 5e-82, Method: Compositional matrix adjust.
Identities = 172/391 (43%), Positives = 232/391 (59%), Gaps = 38/391 (9%)
Query: 18 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77
L F +HR + + L V +T ++SIG+SV+GR+L+VL P H PE K
Sbjct: 2 LAFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVK 61
Query: 78 YVANMHGDETVGRELLLHLIDYLVTS-DGKDPEITNLINSTRIHIMPSMNPDGFE--AVK 134
YV NMHG+E +GREL+L L ++L ++ I LI TRIHI+PSMNPDG+E A +
Sbjct: 62 YVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQ 121
Query: 135 KPDC-YYSIGRENYNQYDLNRNFPDAFEY-----------------NNVSRQ--PETVAV 174
P+ Y +GR N N DLNRNFPD Y +N Q PET AV
Sbjct: 122 GPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLPDNWKSQVEPETRAV 181
Query: 175 MKWLKTETFVLSANLHGGALVASYPFD-------NGVQATGALYSRSLTPDDDVFQYLAH 227
++W+ + FVLSANLHGGA+VA+YP+D GV+ T + + TPDD +FQ LA
Sbjct: 182 IRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTAS----TPTPDDKLFQKLAK 237
Query: 228 TYASRNPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKY 287
Y+ + M +G C + FP+G+TNG SWY L GMQD+NY+ CFEITLELSC K+
Sbjct: 238 VYSYAHGWMFQGWNCGDY--FPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKF 295
Query: 288 PREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNK 347
P EE+L W NK +LI++++QVH G+KG V DQN N L N ++ V H +
Sbjct: 296 PPEEELQREWLGNKEALIQFLEQVHQGIKGMVLDQNYNNLANAVISVSGINHDVT--SGD 353
Query: 348 YGEYYLLLLPGSYIINVTVPGHDPHITKVII 378
+G+Y+ LLLPG Y ++ T PG+DP V +
Sbjct: 354 HGDYFRLLLPGIYTVSATAPGYDPETVTVTV 384
>3V7Z-A nrPDB
Length = 326
Score = 72.0 bits (175), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 78/308 (25%), Positives = 122/308 (39%), Gaps = 65/308 (21%)
Query: 17 ALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGI--- 73
+ D YH M + TVA NY ++ SIGKS +GR LW + + +G
Sbjct: 4 SYDSGYHNYNEMVNKINTVASNYPNIVKKFSIGKSYEGRELWAVKIS-----DNVGTDEN 58
Query: 74 -PEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEA 132
PE Y A H E + E+ L+ +D + D ITNL+N+ I+I+ ++NPDG E
Sbjct: 59 EPEVLYTALHHAREHLTVEMALYTLDLFTQNYNLDSRITNLVNNREIYIVFNINPDGGEY 118
Query: 133 VKKPDCYYSIGR-------ENYNQYDLNRNF---------------PDAFEYNNVSRQPE 170
Y S + +Y DLNRN+ + + + PE
Sbjct: 119 DISSGSYKSWRKNRQPNSGSSYVGTDLNRNYGYKWGCCGGSSGSPSSETYRGRSAFSAPE 178
Query: 171 TVAVMKWLKTETFVLSANLHGGALVASYPFDNGV-QATGALYS---RSLTPDD-DVFQYL 225
T A+ ++ + V+ L+ + + + G Y+ +T DD +VF+ +
Sbjct: 179 TAAMRDFINSR--VVGGKQQIKTLITFHTYSELILYPYGYTYTDVPSDMTQDDFNVFKTM 236
Query: 226 AHTYASRNPNMKKGDECKNKMNFPNGVTNGYS------WYPLQGGMQDYNYIWAQCFEIT 279
A+T A TNGY+ Y G M D+ Y + F T
Sbjct: 237 ANTMAQ---------------------TNGYTPQQASDLYITDGDMTDWAYGQHKIFAFT 275
Query: 280 LELSCCKY 287
E+ Y
Sbjct: 276 FEMYPTSY 283
>4A39-A nrPDB
Length = 388
Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 41/145 (28%), Positives = 67/145 (46%), Gaps = 18/145 (12%)
Query: 47 SIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGK 106
++G SV+GR++ +L V R P H + +A H E + + LI+ L D
Sbjct: 148 AVGTSVQGRDIELLRVRRHPDSHL----KLWVIAQQHPGEHMAEWFMEGLIERLQRPD-- 201
Query: 107 DPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVS 166
D E+ L+ ++++P+MNPDG ++ R N DLNR A+ +
Sbjct: 202 DTEMQRLLEKADLYLVPNMNPDG--------AFHGNLRTNAAGQDLNR----AWLEPSAE 249
Query: 167 RQPETVAVMKWLKTETFVLSANLHG 191
R PE V + +K L ++HG
Sbjct: 250 RSPEVWFVQQEMKRHGVDLFLDIHG 274
>1KWM-A nrPDB
Length = 402
Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 57/282 (20%), Positives = 107/282 (37%), Gaps = 42/282 (14%)
Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
Y++ E +EA+ + VA ++ IG + +GR +++L VG+ + P
Sbjct: 104 YNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNK----PAIFMDCG 159
Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
H E + + V + G++ ++T L+N +++P +N DG+ ++
Sbjct: 160 FHAREWISPAFCQWFVREAVRTYGREIQVTELLNKLDFYVLPVLNIDGYIYTWTKSRFWR 219
Query: 142 IGRENYN-----QYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTET 182
R + D NRNF + SR P ET A+ +++ +
Sbjct: 220 KTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKL 279
Query: 183 FVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD 240
+ A +H + + YP+ Y+ L ++ LA ++
Sbjct: 280 SSIKAYLTIHSYSQMMIYPYS---------YAYKLGENNAELNALAKATVKELASLH--- 327
Query: 241 ECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
K + G T + YP GG D+ Y + T EL
Sbjct: 328 --GTKYTYGPGAT---TIYPAAGGSDDWAYDQGIRYSFTFEL 364
>1ZLI-A nrPDB
Length = 309
Score = 48.5 bits (114), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 57/282 (20%), Positives = 106/282 (37%), Gaps = 42/282 (14%)
Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
Y+ E +EA+ + VA ++ IG + +GR +++L VG+ + P
Sbjct: 11 YNNWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNK----PAIFMDCG 66
Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
H E + + V + G++ ++T L+N +++P +N DG+ ++
Sbjct: 67 FHAREWISPAFCQWFVREAVRTYGREIQVTELLNKLDFYVLPVLNIDGYIYTWTKSRFWR 126
Query: 142 IGRENYN-----QYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTET 182
R + D NRNF + SR P ET A+ +++ +
Sbjct: 127 KTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKL 186
Query: 183 FVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD 240
+ A +H + + YP+ Y+ L ++ LA ++
Sbjct: 187 SSIKAYLTIHSYSQMMIYPYS---------YAYKLGENNAELNALAKATVKELASLH--- 234
Query: 241 ECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
K + G T + YP GG D+ Y + T EL
Sbjct: 235 --GTKYTYGPGAT---TIYPAAGGSDDWAYDQGIRYSFTFEL 271
>4BD9-A nrPDB
Length = 310
Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 36/159 (22%), Positives = 67/159 (42%), Gaps = 11/159 (6%)
Query: 19 DFNYHRQEGMEAF---LKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75
+FNY +EA + +A ++ + IG S + R ++VL +F + P
Sbjct: 6 NFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVL---KFSTGKGVRRPA 62
Query: 76 FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135
A +H E + + + +V+ +DP IT+++ I ++P NPDG+ +
Sbjct: 63 VWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQT 122
Query: 136 PDCYYSIGR-----ENYNQYDLNRNFPDAFEYNNVSRQP 169
+ + R + D NRN+ +F S P
Sbjct: 123 QNRLWRKTRSRNPGSSCIGADPNRNWNASFAGKGASDNP 161
>2BOA-A nrPDB
Length = 404
Score = 45.4 bits (106), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 28/115 (24%), Positives = 53/115 (46%), Gaps = 6/115 (5%)
Query: 19 DFNYHRQEGMEAF---LKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75
+FNY +EA + +A ++ + IG S + R ++VL +F + P
Sbjct: 100 NFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVL---KFSTGKGVRRPA 156
Query: 76 FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGF 130
A +H E + + + +V+ +DP IT+++ I ++P NPDG+
Sbjct: 157 VWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGY 211
>3OSL-A nrPDB
Length = 401
Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 62/284 (21%), Positives = 110/284 (38%), Gaps = 41/284 (14%)
Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
YH + ++++ + + Y + IG S + L+VL V + KE R +
Sbjct: 100 QYHSLNEIYSWIEVMTERYPDMVEKIHIGSSYEKYPLYVLKVSK--KEQRAKNAMW-IDC 156
Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
+H E + L + + GK+ TNL+ +IMP +N DG++ K D +
Sbjct: 157 GIHAREWISPAFCLWFVGSVTYYYGKEKMHTNLLKHMDFYIMPVVNVDGYDYTWKKDRMW 216
Query: 141 SIGRENYNQ-----YDLNRNFP------DAFEYNNVSR---------QPETVAVMKWLKT 180
R + + DLNRNF + ++ S +PE AV +L+
Sbjct: 217 RKNRSLHEKNACVGTDLNRNFASKHWCGEGASSSSCSEIYCGTYPESEPEVKAVADFLRR 276
Query: 181 ETFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKK 238
+ A ++H + +P+ YSRS + D + +A N+ +
Sbjct: 277 NIKHIKAYISMHSYSQKIVFPYS---------YSRSRSKDHEELSLVAREAVFAMENIHR 327
Query: 239 GDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
+ + +G + S Y GG D+ Y + T EL
Sbjct: 328 N------IRYTHG-SGSESLYLAPGGSDDWIYDLGIKYSFTFEL 364
>4B6Z-A nrPDB
Length = 405
Score = 44.7 bits (104), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 50/179 (27%), Positives = 77/179 (43%), Gaps = 27/179 (15%)
Query: 20 FNYHRQEGMEAFLKTVAQ-NYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKY 78
F + +E AFL V Q +SV L G++V+GR + +L +G + G P+ K
Sbjct: 132 FEPYSEERHAAFLGAVQQLPQASVVEL---GRTVEGRPMSLLTLGTPETD---GAPKKKV 185
Query: 79 --VANMHGDETVGRELLLHLIDYLVTSD--GKDPEITNLINSTRIHIMPSMNPDGFEAVK 134
+A H E++ + L+ L DP L + HI+P+MNPDG
Sbjct: 186 WIIARQHPGESMAEWFVEGLVKRLAGWGDWAGDPVARKLYDRVTFHIVPNMNPDG----- 240
Query: 135 KPDCYYSIGRENYNQYDLNRNF--PDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHG 191
+ R N +LNR + PDA R PE +AV + + ++HG
Sbjct: 241 ---SVHGNLRTNAAGANLNREWMAPDA------ERSPEVLAVRDAIHAIGCDMFFDIHG 290
>3D4U-A nrPDB
Length = 309
Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 62/284 (21%), Positives = 110/284 (38%), Gaps = 41/284 (14%)
Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
YH + ++++ + + Y + IG S + L+VL V + KE R +
Sbjct: 8 QYHSLNEIYSWIEVMTERYPDMVEKIHIGSSYEKYPLYVLKVSK--KEQRAKNAMW-IDC 64
Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
+H E + L + + GK+ TNL+ +IMP +N DG++ K D +
Sbjct: 65 GIHAREWISPAFCLWFVGSVTYYYGKEKMHTNLLKHMDFYIMPVVNVDGYDYTWKKDRMW 124
Query: 141 SIGRENYNQ-----YDLNRNFP------DAFEYNNVSR---------QPETVAVMKWLKT 180
R + + DLNRNF + ++ S +PE AV +L+
Sbjct: 125 RKNRSLHEKNACVGTDLNRNFASKHWCGEGASSSSCSEIYCGTYPESEPEVKAVADFLRR 184
Query: 181 ETFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKK 238
+ A ++H + +P+ YSRS + D + +A N+ +
Sbjct: 185 NIKHIKAYISMHSYSQKIVFPYS---------YSRSRSKDHEELSLVAREAVFAMENIHR 235
Query: 239 GDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
+ + +G + S Y GG D+ Y + T EL
Sbjct: 236 N------IRYTHG-SGSESLYLAPGGSDDWIYDLGIKYSFTFEL 272
>1DTD-A nrPDB
Length = 303
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 36/154 (23%), Positives = 63/154 (40%), Gaps = 11/154 (7%)
Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
YH E + + + + + +IG S + R + VL + P A
Sbjct: 6 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-----PAIWLDAG 60
Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
+H E V + L + +V+ GKDP IT+++++ I ++P NPDG+ + + +
Sbjct: 61 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR 120
Query: 142 IGRENYNQ------YDLNRNFPDAFEYNNVSRQP 169
R + D NRN+ F S P
Sbjct: 121 KTRSKVSAGSLCVGVDPNRNWDAGFGGPGASSNP 154
>1JQG-A nrPDB
Length = 433
Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 53/218 (24%), Positives = 85/218 (38%), Gaps = 43/218 (19%)
Query: 23 HRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN- 81
H E ++A+L+ +A+ + +V + GKS +GR++ K RI F+ +
Sbjct: 122 HSYEEVDAYLQELAKEFPNVVTVVEGGKSFEGRSI---------KYLRISTTNFQDASKP 172
Query: 82 -------MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVK 134
+H E V L+ I LV D ++LIN+ I+P NPDG+
Sbjct: 173 VVMMQSLLHCREWVTLPATLYAIHKLVI----DVTESDLINNIDWIILPVANPDGYVHTF 228
Query: 135 KPDCYYSIGRENYNQ-------YDLNRNF-------------PDAFEYNNVSRQPETVAV 174
D Y+ R DLNRNF D F + +PE+ +
Sbjct: 229 GGDRYWRKNRATGYMAGNLCMGVDLNRNFGMNWGTASSSSVCSDTFHGRSAFSEPESSVI 288
Query: 175 MKWLKTE--TFVLSANLHGGALVASYPFDNGVQATGAL 210
+ L ++H + Y + NGV + AL
Sbjct: 289 RDIIAEHRNRMALYLDIHSFGSMILYGYGNGVLPSNAL 326
>3K2K-A nrPDB
Length = 403
Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 48/177 (27%), Positives = 75/177 (42%), Gaps = 23/177 (12%)
Query: 20 FNYHRQEGMEAFLKTVAQN-YSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKY 78
F + +E FL V Q +SV L G++V+GR + ++V+G P E +
Sbjct: 130 FEPYSEERHSEFLGAVQQMPQASVVEL---GRTVEGRPMSLVVLGT-PDEAGAAKKKVWI 185
Query: 79 VANMHGDETVGRELLLHLIDYLVTSD--GKDPEITNLINSTRIHIMPSMNPDGFEAVKKP 136
+A H E++ + L+ LV DP L + +I+P+MNPDG
Sbjct: 186 IARQHPGESMAEWFIEGLVKRLVGWGDWSGDPVARKLYDHATFYIVPNMNPDG------- 238
Query: 137 DCYYSIGRENYNQYDLNRNF--PDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHG 191
+ R N +LNR + PDA R PE + V + L ++HG
Sbjct: 239 -SVHGNLRTNAAGANLNREWMEPDA------ERSPEVLVVRDAIHAIGCDLFFDIHG 288
>1AYE-A nrPDB
Length = 401
Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 36/153 (23%), Positives = 63/153 (41%), Gaps = 10/153 (6%)
Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
YH E + + + + + +IG S + R + VL + P A
Sbjct: 105 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-----PAIWLDAG 159
Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
+H E V + L + +V+ GKDP IT+++++ I ++P NPDG+ + + +
Sbjct: 160 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR 219
Query: 142 IGRENYN-----QYDLNRNFPDAFEYNNVSRQP 169
R + D NRN+ F S P
Sbjct: 220 KTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNP 252
>5AQ0-A nrPDB
Length = 82
Score = 40.8 bits (94), Expect = 0.001, Method: Composition-based stats.
Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 4/69 (5%)
Query: 314 GVKGQVFDQ-NGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDP- 371
GVKG V D G+ L N + V H T ++G++Y LL+PG+Y + V + G+ P
Sbjct: 2 GVKGFVKDSITGSGLENATISVAGINH--NITTGRFGDFYRLLVPGTYNLTVVLTGYMPL 59
Query: 372 HITKVIIPE 380
+T V++ E
Sbjct: 60 TVTNVVVKE 68
>4UIB-A nrPDB
Length = 307
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 25/109 (22%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
Y+ E +EA+ K V + +IG + G N+++L VG+ P ++ P
Sbjct: 9 YNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGK-PGPNK---PAIFMDCG 64
Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGF 130
+H E + + V + G + +T +N +++P +N DG+
Sbjct: 65 IHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGY 113
>3GLJ-A nrPDB
Length = 401
Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 25/109 (22%), Positives = 48/109 (44%), Gaps = 4/109 (3%)
Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
Y+ E +EA+ K V + +IG + G N+++L VG+ P ++ P
Sbjct: 104 YNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGK-PGPNK---PAIFMDCG 159
Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGF 130
H E + + V + G + +T +N +++P +N DG+
Sbjct: 160 FHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGY 208
>1NSA-A nrPDB
Length = 395
Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 23/109 (21%), Positives = 50/109 (45%), Gaps = 4/109 (3%)
Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
Y+ E +EA+ + V + +IG + G N+++L VG+ P ++ P
Sbjct: 98 YNNWETIEAWTEQVTSKNPDLISRSAIGTTFDGDNIYLLKVGK-PGSNK---PAIFMDCG 153
Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGF 130
H E + + + V + G + +T +++ +++P +N DG+
Sbjct: 154 FHAREWISQAFCQWFVRDAVRTYGYEAHMTEFLDNLDFYVLPVLNIDGY 202
>3KGQ-A nrPDB
Length = 309
Score = 36.2 bits (82), Expect = 0.027, Method: Compositional matrix adjust.
Identities = 32/154 (20%), Positives = 55/154 (35%), Gaps = 9/154 (5%)
Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
YH + + F+ + + + IG+S +GR ++VL P
Sbjct: 11 TYHTLDEIYDFMDLLVAEHPQLVSKLQIGRSYEGRPIYVLKFSTGGSNR----PAIWIDL 66
Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
+H E + + + G+DP T +++S I + NPDGF + +
Sbjct: 67 GIHSREWITQATGVWFAKKFTEDYGQDPSFTAILDSMDIFLEIVTNPDGFAFTHSQNRLW 126
Query: 141 SIGRENYNQ-----YDLNRNFPDAFEYNNVSRQP 169
R + D NRN+ F S P
Sbjct: 127 RKTRSVTSSSLCVGVDANRNWDAGFGKAGASSSP 160
>3L2N-A nrPDB
Length = 395
Score = 36.2 bits (82), Expect = 0.032, Method: Compositional matrix adjust.
Identities = 25/83 (30%), Positives = 44/83 (53%), Gaps = 8/83 (9%)
Query: 48 IGKSVKGRNLWVLVVGRF-PKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGK 106
+G ++ GR++ ++ VG P + I I A H ET+ L+ L++ L+ +D
Sbjct: 154 LGLTLDGRDMTLVKVGDDDPSKKSIWI-----TARQHPGETMAEWLVEGLLNQLLDNDC- 207
Query: 107 DPEITNLINSTRIHIMPSMNPDG 129
P L++ +I+P+MNPDG
Sbjct: 208 -PTSKALLDKANFYIVPNMNPDG 229
>3D68-A nrPDB
Length = 424
Score = 35.0 bits (79), Expect = 0.068, Method: Compositional matrix adjust.
Identities = 34/143 (23%), Positives = 61/143 (42%), Gaps = 10/143 (6%)
Query: 21 NYHRQEGMEAFLKTVAQNY-SSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79
YH + ++++ + + + +T +H IG S + L+VL V + + I
Sbjct: 123 QYHSLNEIYSWIEFITERHPDMLTKIH-IGSSFEKYPLYVLKVSGKEQTAKNAI---WID 178
Query: 80 ANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCY 139
+H E + L I ++ G + TNL+ ++MP +N DG++ K +
Sbjct: 179 CGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRM 238
Query: 140 YSIGRENYNQ-----YDLNRNFP 157
+ R Y DLNRNF
Sbjct: 239 WRKNRSFYANNHCIGTDLNRNFA 261
>3LMS-A nrPDB
Length = 309
Score = 35.0 bits (79), Expect = 0.072, Method: Compositional matrix adjust.
Identities = 34/144 (23%), Positives = 61/144 (42%), Gaps = 10/144 (6%)
Query: 21 NYHRQEGMEAFLKTVAQNY-SSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79
YH + ++++ + + + +T +H IG S + L+VL V + + I
Sbjct: 8 QYHSLNEIYSWIEFITERHPDMLTKIH-IGSSFEKYPLYVLKVSGKEQAAKNAIW---ID 63
Query: 80 ANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCY 139
+H E + L I ++ G + TNL+ ++MP +N DG++ K +
Sbjct: 64 CGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRM 123
Query: 140 YSIGRENYNQ-----YDLNRNFPD 158
+ R Y DLNRNF
Sbjct: 124 WRKNRSFYANNHCIGTDLNRNFAS 147
>4UEE-A nrPDB
Length = 309
Score = 33.5 bits (75), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 36/155 (23%), Positives = 60/155 (38%), Gaps = 11/155 (7%)
Query: 21 NYHRQEGMEAFLKT-VAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79
YH E + FL VA+N V+ + IG + +GR ++VL + P
Sbjct: 11 TYHTLEEIYDFLDLLVAENPHLVSKIQ-IGNTYEGRPIYVLKFSTGGSKR----PAIWID 65
Query: 80 ANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCY 139
+H E V + + + G+D T ++++ I + NPDGF +
Sbjct: 66 TGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRM 125
Query: 140 YSIGRENYN-----QYDLNRNFPDAFEYNNVSRQP 169
+ R + D NRN+ F + S P
Sbjct: 126 WRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNP 160
>2QVP-A nrPDB
Length = 275
Score = 33.5 bits (75), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 19/62 (30%), Positives = 30/62 (48%), Gaps = 9/62 (14%)
Query: 69 HRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPD 128
+ G+P A HG+E+ G LLH + L D E+ +N + ++P +NP
Sbjct: 61 QKAGLPNLLISAGFHGEESAGPWGLLHFLSQL------DGELFKRVN---LSVLPLVNPT 111
Query: 129 GF 130
GF
Sbjct: 112 GF 113
>5MRV-A nrPDB
Length = 355
Score = 33.5 bits (75), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 33/179 (18%), Positives = 72/179 (40%), Gaps = 22/179 (12%)
Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
YH + +++ +++ Y V H +G + + ++ L + + P + I
Sbjct: 56 YHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPIYYLKISQ-PSGNPKKIIWMD--CG 112
Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
+H E + + ++ + + I L+ + +++P +N DG+ D +
Sbjct: 113 IHAREWIAPAFCQWFVKEILQNHKDNSRIRKLLRNLDFYVLPVLNIDGYIYTWTTDRLWR 172
Query: 142 IGRENYNQ-----YDLNRNFPDAFEYNNVSR--------------QPETVAVMKWLKTE 181
R +N DLNRNF ++ SR +PET AV +++++
Sbjct: 173 KSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVASFIESK 231
>5OM9-A nrPDB
Length = 419
Score = 32.7 bits (73), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 36/155 (23%), Positives = 60/155 (38%), Gaps = 11/155 (7%)
Query: 21 NYHRQEGMEAFLKT-VAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79
YH E + FL VA+N V+ + IG + +GR ++VL + P
Sbjct: 121 TYHTLEEIYDFLDLLVAENPHLVSKIQ-IGNTYEGRPIYVLKFSTGGSKR----PAIWID 175
Query: 80 ANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCY 139
+H E V + + + G+D T ++++ I + NPDGF +
Sbjct: 176 TGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRM 235
Query: 140 YSIGRENYN-----QYDLNRNFPDAFEYNNVSRQP 169
+ R + D NRN+ F + S P
Sbjct: 236 WRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNP 270
>1PCA-A nrPDB
Length = 403
Score = 32.0 bits (71), Expect = 0.53, Method: Compositional matrix adjust.
Identities = 30/154 (19%), Positives = 58/154 (37%), Gaps = 9/154 (5%)
Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
YH E + F+ + + ++ IG+S +GR ++VL P +
Sbjct: 106 TYHTLEEIYDFMDILVAEHPALVSKLQIGRSYEGRPIYVLKFSTGGSNR----PAIWIDS 161
Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
+H E + + + + + G++ T +++S I + NP+GF + +
Sbjct: 162 GIHSREWITQASGVWFAKKITENYGQNSSFTAILDSMDIFLEIVTNPNGFAFTHSDNRLW 221
Query: 141 SIGRENYN-----QYDLNRNFPDAFEYNNVSRQP 169
R + D NRN+ F S P
Sbjct: 222 RKTRSKASGSLCVGSDSNRNWDAGFGGAGASSSP 255
>5HXD-A nrPDB
Length = 237
Score = 32.0 bits (71), Expect = 0.60, Method: Compositional matrix adjust.
Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 17/63 (26%)
Query: 118 RIHIMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDA--------FEYNNVSRQP 169
R H++ +NPDG C + R N N DLNRNFP A + +N+ + +
Sbjct: 72 RHHVVLCVNPDG--------CQLGL-RANANGVDLNRNFPAANWKEGETVYRWNSAAEER 122
Query: 170 ETV 172
+ V
Sbjct: 123 DVV 125
>4GFJ-A nrPDB
Length = 685
Score = 31.2 bits (69), Expect = 0.86, Method: Compositional matrix adjust.
Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 4/73 (5%)
Query: 29 EAF-LKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEH-RIGIPEFKYVANMHGDE 86
EAF L+T A+ Y L IG+ + +L L +G PK I PEFK++ N+ G
Sbjct: 574 EAFDLETAAELYERYGSLKEIGRRLSYDDL--LELGATPKAAAEIKGPEFKFLLNIEGVG 631
Query: 87 TVGRELLLHLIDY 99
E +L +DY
Sbjct: 632 PKLAERILEAVDY 644
>5HM5-A nrPDB
Length = 854
Score = 31.2 bits (69), Expect = 0.97, Method: Compositional matrix adjust.
Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 4/73 (5%)
Query: 29 EAF-LKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEH-RIGIPEFKYVANMHGDE 86
EAF L+T A+ Y L IG+ + +L L +G PK I PEFK++ N+ G
Sbjct: 574 EAFDLETAAELYERYGSLKEIGRRLSYDDL--LELGATPKAAAEIKGPEFKFLLNIEGVG 631
Query: 87 TVGRELLLHLIDY 99
E +L +DY
Sbjct: 632 PKLAERILEAVDY 644
>3IEH-A nrPDB
Length = 276
Score = 31.2 bits (69), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 29/127 (22%), Positives = 43/127 (33%), Gaps = 20/127 (15%)
Query: 70 RIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDG 129
+ G+P A HG+E+ G LLH + +L + ++P +NP G
Sbjct: 63 KSGLPSLLISAGFHGEESAGPWGLLHFL---------SEASADLFERVNLSLLPLVNPTG 113
Query: 130 FEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANL 189
F + +N+Y N N FE T K L +L A
Sbjct: 114 FSRGHR-----------FNKYGENPNRGFVFENGKPKANEHTSVEGKLLLDHAQLLIAAC 162
Query: 190 HGGALVA 196
G L
Sbjct: 163 RDGILTC 169
>2C1C-A nrPDB
Length = 312
Score = 30.0 bits (66), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 38/183 (20%), Positives = 71/183 (38%), Gaps = 20/183 (10%)
Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVG--RFPKEHRIGIPEFKY 78
NY E ++ +L + + Y V + + +S +GR + + + F E++ P
Sbjct: 5 NYQELEVIDEYLDYIGEKYPDVATVVNAAESFEGRPIKYIKISTTNFEDENK---PVIFI 61
Query: 79 VANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDC 138
+H E + + I LV +D +L+ ++P +NPDG++ +
Sbjct: 62 DGGIHAREWISPPSVTWAIHKLV----EDVTENDLLEKFDWILLPVVNPDGYKYTFTNER 117
Query: 139 YYSIGRENYNQ--------YDLNRNFPDAFEYNNVSRQPET---VAVMKWLKTETFVLSA 187
++ R N D NRNF + S P + + + ET V+
Sbjct: 118 FWRKTRSTNNNPLSQICRGADGNRNFDFVWNSIGTSNSPCSDIYAGTSAFSEVETRVVRD 177
Query: 188 NLH 190
LH
Sbjct: 178 ILH 180
>6D97-A nrPDB
Length = 547
Score = 29.6 bits (65), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 36/151 (23%), Positives = 64/151 (42%), Gaps = 16/151 (10%)
Query: 255 GYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLG 314
G+ W L +Q+ +Y+ C + S K + L N + + L+E +K+ L
Sbjct: 296 GFDWKILGPDVQEVDYVAWVCDQDAYACSGQKCSAQSVLFMHKNWSSSGLLEKMKK--LS 353
Query: 315 VKGQVFDQNGNPLPNVIVE--VQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVP----G 368
+ ++ D P+ V E ++ ++ R +K +L G + N ++P
Sbjct: 354 ERRKLEDLTIGPVLTVTTEAMIEHMNNLLKIRGSK------VLFGGEPLANHSIPKIYGA 407
Query: 369 HDPHITKVIIPE--KSQNFSALKKDILLPFQ 397
P V + E KS NF + K+I PFQ
Sbjct: 408 MKPTAVFVPLEEILKSGNFELVTKEIFGPFQ 438
>3B2Y-A nrPDB
Length = 275
Score = 29.3 bits (64), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 17/64 (26%), Positives = 29/64 (45%), Gaps = 9/64 (14%)
Query: 69 HRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPD 128
R +P + HG+E G +LH + G P + +N + ++P +NP
Sbjct: 62 QRSDLPSLLISSGFHGEEAAGPWGMLHFLR------GLQPALFERVN---LSLLPLVNPT 112
Query: 129 GFEA 132
GF+A
Sbjct: 113 GFKA 116
>3N5M-A nrPDB
Length = 452
Score = 28.5 bits (62), Expect = 6.5, Method: Compositional matrix adjust.
Identities = 34/135 (25%), Positives = 50/135 (37%), Gaps = 24/135 (17%)
Query: 128 DGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTET---FV 184
GF V PDCY G E N YD V E VM W +ET F+
Sbjct: 174 SGFLHVTPPDCYRMPGIERENIYD-------------VECVKEVDRVMTWELSETIAAFI 220
Query: 185 LSANLHGGA-LVASYPFDNGVQATGALYSRSLTPDDDV--FQYLAHTYASRNPNMKKGDE 241
+ + GG L+A + V T + L D+ + F + N ++K
Sbjct: 221 MEPIITGGGILMAPQDYMKAVHETCQKHGALLISDEVICGFGRTGKAFGFMNYDVK---- 276
Query: 242 CKNKMNFPNGVTNGY 256
+ + G+T+ Y
Sbjct: 277 -PDIITMAKGITSAY 290
>1SEZ-A nrPDB
Length = 504
Score = 28.1 bits (61), Expect = 8.8, Method: Compositional matrix adjust.
Identities = 17/57 (29%), Positives = 27/57 (47%), Gaps = 3/57 (5%)
Query: 192 GALVASYPFDNGVQATGALYSRSLTPD---DDVFQYLAHTYASRNPNMKKGDECKNK 245
G LV S +G++ G L+S + PD ++V+ Y SRN + K + K
Sbjct: 354 GVLVPSKEQQHGLKTLGTLFSSMMFPDRAPNNVYLYTTFVGGSRNRELAKASRTELK 410
>1YKN-B nrPDB
Length = 238
Score = 27.7 bits (60), Expect = 9.4, Method: Compositional matrix adjust.
Identities = 11/20 (55%), Positives = 15/20 (75%)
Query: 315 VKGQVFDQNGNPLPNVIVEV 334
V G+V DQ G P+PN +VE+
Sbjct: 80 VAGRVVDQYGKPVPNTLVEM 99
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
1UWY-A nrPDB 652 0.0
3MN8-A nrPDB 484 e-137
1QMU-A nrPDB 483 e-137
2NSM-A nrPDB 444 e-125
1KWM-A nrPDB 283 1e-76
1ZLI-A nrPDB 282 2e-76
3OSL-A nrPDB 267 1e-71
3D4U-A nrPDB 265 3e-71
4UIB-A nrPDB 260 6e-70
2BOA-A nrPDB 250 1e-66
4BD9-A nrPDB 248 3e-66
3V7Z-A nrPDB 242 2e-64
1AYE-A nrPDB 238 3e-63
1DTD-A nrPDB 237 9e-63
1JQG-A nrPDB 203 2e-52
3K2K-A nrPDB 175 3e-44
4B6Z-A nrPDB 166 2e-41
4A39-A nrPDB 152 2e-37
5AQ0-A nrPDB 90 2e-18
Sequences not found previously or not previously below threshold:
3GLJ-A nrPDB 267 7e-72
1NSA-A nrPDB 261 4e-70
3D68-A nrPDB 235 5e-62
3LMS-A nrPDB 233 1e-61
3KGQ-A nrPDB 223 2e-58
5OM9-A nrPDB 215 5e-56
4UEE-A nrPDB 212 3e-55
1PCA-A nrPDB 211 4e-55
5MRV-A nrPDB 197 7e-51
1CPB-B nrPDB 171 7e-43
2C1C-A nrPDB 165 3e-41
3L2N-A nrPDB 121 6e-28
1CPB-A nrPDB 93 3e-19
2QVP-A nrPDB 51 1e-06
3B2Y-A nrPDB 49 5e-06
5HXD-A nrPDB 47 2e-05
3IEH-A nrPDB 45 6e-05
4OKO-A nrPDB 41 0.001
2QJ8-A nrPDB 37 0.014
4RWR-A nrPDB 36 0.025
4AXV-A nrPDB 36 0.035
2OKL-A nrPDB 34 0.20
5OCR-A nrPDB 32 0.53
5JBE-A nrPDB 31 0.79
5VOC-B nrPDB 31 1.3
3A22-A nrPDB 30 1.5
2AZQ-A nrPDB 30 2.7
3ZHL-A nrPDB 29 3.2
4E79-A nrPDB 29 5.3
4M1U-A nrPDB 29 5.5
2HN1-A nrPDB 29 6.2
1JQP-A nrPDB 28 9.4
>1UWY-A nrPDB
Length = 426
Score = 652 bits (1683), Expect = 0.0, Method: Composition-based stats.
Identities = 426/426 (100%), Positives = 426/426 (100%)
Query: 18 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77
LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK
Sbjct: 1 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 60
Query: 78 YVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPD 137
YVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPD
Sbjct: 61 YVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPD 120
Query: 138 CYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVAS 197
CYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVAS
Sbjct: 121 CYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVAS 180
Query: 198 YPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYS 257
YPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYS
Sbjct: 181 YPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYS 240
Query: 258 WYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKG 317
WYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKG
Sbjct: 241 WYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKG 300
Query: 318 QVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVI 377
QVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVI
Sbjct: 301 QVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVI 360
Query: 378 IPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLPDHSAATKPSLFLFLVSL 437
IPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLPDHSAATKPSLFLFLVSL
Sbjct: 361 IPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLPDHSAATKPSLFLFLVSL 420
Query: 438 LHIFFK 443
LHIFFK
Sbjct: 421 LHIFFK 426
>3MN8-A nrPDB
Length = 435
Score = 484 bits (1245), Expect = e-137, Method: Composition-based stats.
Identities = 169/396 (42%), Positives = 246/396 (62%), Gaps = 21/396 (5%)
Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
+Y QE +E + + Y + +H +G+S++GRNL L + R + + P KY+A
Sbjct: 39 HYASQEQLEDLFAGLEKAYPNQAKVHFLGRSLEGRNLLALQISRNTRSRNLLTPPVKYIA 98
Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
NMHGDETVGR+LL+++ YL+ + + ++ L+NST I+++P+MNPDG+ ++ +C
Sbjct: 99 NMHGDETVGRQLLVYMAQYLLGNHERISDLGQLVNSTDIYLVPTMNPDGYALSQEGNCES 158
Query: 141 ---SIGRENYNQYDLNRNFPDAFEYNNV------SRQPETVAVMKWLKTETFVLSANLHG 191
+GR N DLNR+FPD E ++V SRQPET A++ W+ ++ FVLSAN HG
Sbjct: 159 LPNYVGRGNAANIDLNRDFPDRLEQSHVHQLRAQSRQPETAALVNWIVSKPFVLSANFHG 218
Query: 192 GALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNG 251
GA+VASYP+DN + A SLTPDD VF+ LAHTY+ +P M+KG+ C + +F G
Sbjct: 219 GAVVASYPYDNSL-AHNECCEESLTPDDRVFKQLAHTYSDNHPIMRKGNNCND--SFSGG 275
Query: 252 VTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQV 311
+TNG WY L GGMQD+NY ++ CFE+T+ELSCCKYP LP W NKASL++ ++Q
Sbjct: 276 ITNGAHWYELSGGMQDFNYAFSNCFELTIELSCCKYPAASTLPQEWQRNKASLLQLLRQA 335
Query: 312 HLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHD- 370
H+G+KG V D +G P+ + V V + P RT+K GEY+ LL PG Y ++ + G+
Sbjct: 336 HIGIKGLVTDASGFPIADANVYVAGLEEK-PMRTSKRGEYWRLLTPGLYSVHASAFGYQT 394
Query: 371 --PHITKVIIPEKSQNFSALKKDI-LLPFQGQLDSI 403
P +V + N AL+ D L P + D I
Sbjct: 395 SAPQQVRVT----NDNQEALRLDFKLAPVETNFDGI 426
>1QMU-A nrPDB
Length = 380
Score = 483 bits (1244), Expect = e-137, Method: Composition-based stats.
Identities = 187/371 (50%), Positives = 246/371 (66%), Gaps = 9/371 (2%)
Query: 15 VAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIP 74
V +DF +H ME FL+ A Y S+T L+S+GKSV+ R L+V+ + P H G P
Sbjct: 3 VQPVDFRHHHFSDMEIFLRRYANEYPSITRLYSVGKSVELRELYVMEISDNPGIHEAGEP 62
Query: 75 EFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVK 134
EFKY+ NMHG+E VGRELLL+LI+YL + G DPE+T+L+ STRIHIMPSMNPDG+E +
Sbjct: 63 EFKYIGNMHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVQSTRIHIMPSMNPDGYEKSQ 122
Query: 135 KPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGAL 194
+ D ++GR N N YDLNRNFPD F QPET+AVM WLKT FVLSANLHGG+L
Sbjct: 123 EGDRGGTVGRNNSNNYDLNRNFPDQFFQVTDPPQPETLAVMSWLKTYPFVLSANLHGGSL 182
Query: 195 VASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKN---KMNFPNG 251
V +YPFD+ Q A+YS+S PDD VFQ LA +Y+ N M +G CK+ FP+G
Sbjct: 183 VVNYPFDDDEQGI-AIYSKS--PDDAVFQQLALSYSKENKKMYQGSPCKDLYPTEYFPHG 239
Query: 252 VTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQV 311
+TNG WY + GGMQD+NY+ CFE+T+EL C KYP+ E+LP +W N+ SL+++IKQV
Sbjct: 240 ITNGAQWYNVPGGMQDWNYLNTNCFEVTIELGCVKYPKAEELPKYWEQNRRSLLQFIKQV 299
Query: 312 HLGVKGQVFDQ-NGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHD 370
H G+ G V D +G + N + V D H P T K G+Y+ LL+ G+Y + + G+D
Sbjct: 300 HRGIWGFVLDATDGRGILNATISVADINH--PVTTYKDGDYWRLLVQGTYKVTASARGYD 357
Query: 371 PHITKVIIPEK 381
P V + K
Sbjct: 358 PVTKTVEVDSK 368
>2NSM-A nrPDB
Length = 439
Score = 444 bits (1141), Expect = e-125, Method: Composition-based stats.
Identities = 169/387 (43%), Positives = 229/387 (59%), Gaps = 30/387 (7%)
Query: 18 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77
L F +HR + + L V +T ++SIG+SV+GR+L+VL P H PE K
Sbjct: 2 LAFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVK 61
Query: 78 YVANMHGDETVGRELLLHLIDYLVTSD-GKDPEITNLINSTRIHIMPSMNPDGFE--AVK 134
YV NMHG+E +GREL+L L ++L ++ I LI TRIHI+PSMNPDG+E A +
Sbjct: 62 YVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQ 121
Query: 135 KPDC-YYSIGRENYNQYDLNRNFPDAFEY-----------------NNVSRQ--PETVAV 174
P+ Y +GR N N DLNRNFPD Y +N Q PET AV
Sbjct: 122 GPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLPDNWKSQVEPETRAV 181
Query: 175 MKWLKTETFVLSANLHGGALVASYPFDNGVQ---ATGALYSRSLTPDDDVFQYLAHTYAS 231
++W+ + FVLSANLHGGA+VA+YP+D + + + TPDD +FQ LA Y+
Sbjct: 182 IRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLAKVYSY 241
Query: 232 RNPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREE 291
+ M +G C + FP+G+TNG SWY L GMQD+NY+ CFEITLELSC K+P EE
Sbjct: 242 AHGWMFQGWNCGDY--FPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPPEE 299
Query: 292 KLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEY 351
+L W NK +LI++++QVH G+KG V DQN N L N ++ V H + +G+Y
Sbjct: 300 ELQREWLGNKEALIQFLEQVHQGIKGMVLDQNYNNLANAVISVSGINHD--VTSGDHGDY 357
Query: 352 YLLLLPGSYIINVTVPGHDPHITKVII 378
+ LLLPG Y ++ T PG+DP V +
Sbjct: 358 FRLLLPGIYTVSATAPGYDPETVTVTV 384
>1KWM-A nrPDB
Length = 402
Score = 283 bits (724), Expect = 1e-76, Method: Composition-based stats.
Identities = 57/283 (20%), Positives = 107/283 (37%), Gaps = 42/283 (14%)
Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
Y++ E +EA+ + VA ++ IG + +GR +++L VG+ + P
Sbjct: 103 KYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNK----PAIFMDC 158
Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
H E + + V + G++ ++T L+N +++P +N DG+ ++
Sbjct: 159 GFHAREWISPAFCQWFVREAVRTYGREIQVTELLNKLDFYVLPVLNIDGYIYTWTKSRFW 218
Query: 141 SIGRENYN-----QYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTE 181
R + D NRNF + SR P ET A+ +++ +
Sbjct: 219 RKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNK 278
Query: 182 TFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKG 239
+ A +H + + YP+ Y+ L ++ LA ++
Sbjct: 279 LSSIKAYLTIHSYSQMMIYPYS---------YAYKLGENNAELNALAKATVKELASLH-- 327
Query: 240 DECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
K + G T + YP GG D+ Y + T EL
Sbjct: 328 ---GTKYTYGPGAT---TIYPAAGGSDDWAYDQGIRYSFTFEL 364
>1ZLI-A nrPDB
Length = 309
Score = 282 bits (722), Expect = 2e-76, Method: Composition-based stats.
Identities = 57/283 (20%), Positives = 106/283 (37%), Gaps = 42/283 (14%)
Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
Y+ E +EA+ + VA ++ IG + +GR +++L VG+ + P
Sbjct: 10 KYNNWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNK----PAIFMDC 65
Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
H E + + V + G++ ++T L+N +++P +N DG+ ++
Sbjct: 66 GFHAREWISPAFCQWFVREAVRTYGREIQVTELLNKLDFYVLPVLNIDGYIYTWTKSRFW 125
Query: 141 SIGRENYN-----QYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTE 181
R + D NRNF + SR P ET A+ +++ +
Sbjct: 126 RKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNK 185
Query: 182 TFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKG 239
+ A +H + + YP+ Y+ L ++ LA ++
Sbjct: 186 LSSIKAYLTIHSYSQMMIYPYS---------YAYKLGENNAELNALAKATVKELASLH-- 234
Query: 240 DECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
K + G T + YP GG D+ Y + T EL
Sbjct: 235 ---GTKYTYGPGAT---TIYPAAGGSDDWAYDQGIRYSFTFEL 271
>3GLJ-A nrPDB
Length = 401
Score = 267 bits (682), Expect = 7e-72, Method: Composition-based stats.
Identities = 55/283 (19%), Positives = 95/283 (33%), Gaps = 42/283 (14%)
Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
Y+ E +EA+ K V + +IG + G N+++L VG+ P
Sbjct: 103 KYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKP----GPNKPAIFMDC 158
Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
H E + + V + G + +T +N +++P +N DG+ + +
Sbjct: 159 GFHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMW 218
Query: 141 SIGRE-----NYNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTE 181
R D NRNF + S P ET A+ +++
Sbjct: 219 RKTRSTNAGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNN 278
Query: 182 TFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKG 239
+ A +H + + YP+ Y L ++ LA +
Sbjct: 279 LSSIKAYLTIHSYSQMILYPYS---------YDYKLPENNAELNNLAKAAVKELATLY-- 327
Query: 240 DECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
K + G T + YP GG D+ Y + T EL
Sbjct: 328 ---GTKYTYGPGAT---TIYPAAGGSDDWAYDQGIKYSFTFEL 364
>3OSL-A nrPDB
Length = 401
Score = 267 bits (681), Expect = 1e-71, Method: Composition-based stats.
Identities = 61/289 (21%), Positives = 108/289 (37%), Gaps = 41/289 (14%)
Query: 16 AALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75
++ YH + ++++ + + Y + IG S + L+VL V + KE R
Sbjct: 95 SSYYEQYHSLNEIYSWIEVMTERYPDMVEKIHIGSSYEKYPLYVLKVSK--KEQRAKN-A 151
Query: 76 FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135
+H E + L + + GK+ TNL+ +IMP +N DG++ K
Sbjct: 152 MWIDCGIHAREWISPAFCLWFVGSVTYYYGKEKMHTNLLKHMDFYIMPVVNVDGYDYTWK 211
Query: 136 PDCYYSIGRENYN-----QYDLNRNF---------------PDAFEYNNVSRQPETVAVM 175
D + R + DLNRNF + + +PE AV
Sbjct: 212 KDRMWRKNRSLHEKNACVGTDLNRNFASKHWCGEGASSSSCSEIYCGTYPESEPEVKAVA 271
Query: 176 KWLKTETFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRN 233
+L+ + A ++H + +P+ YSRS + D + +A
Sbjct: 272 DFLRRNIKHIKAYISMHSYSQKIVFPYS---------YSRSRSKDHEELSLVAREAVFAM 322
Query: 234 PNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
N+ + + + +G + S Y GG D+ Y + T EL
Sbjct: 323 ENIHRN------IRYTHG-SGSESLYLAPGGSDDWIYDLGIKYSFTFEL 364
>3D4U-A nrPDB
Length = 309
Score = 265 bits (676), Expect = 3e-71, Method: Composition-based stats.
Identities = 61/289 (21%), Positives = 108/289 (37%), Gaps = 41/289 (14%)
Query: 16 AALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75
++ YH + ++++ + + Y + IG S + L+VL V + KE R
Sbjct: 3 SSYYEQYHSLNEIYSWIEVMTERYPDMVEKIHIGSSYEKYPLYVLKVSK--KEQRAKN-A 59
Query: 76 FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135
+H E + L + + GK+ TNL+ +IMP +N DG++ K
Sbjct: 60 MWIDCGIHAREWISPAFCLWFVGSVTYYYGKEKMHTNLLKHMDFYIMPVVNVDGYDYTWK 119
Query: 136 PDCYYSIGRENYN-----QYDLNRNF---------------PDAFEYNNVSRQPETVAVM 175
D + R + DLNRNF + + +PE AV
Sbjct: 120 KDRMWRKNRSLHEKNACVGTDLNRNFASKHWCGEGASSSSCSEIYCGTYPESEPEVKAVA 179
Query: 176 KWLKTETFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRN 233
+L+ + A ++H + +P+ YSRS + D + +A
Sbjct: 180 DFLRRNIKHIKAYISMHSYSQKIVFPYS---------YSRSRSKDHEELSLVAREAVFAM 230
Query: 234 PNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
N+ + + + +G + S Y GG D+ Y + T EL
Sbjct: 231 ENIHRN------IRYTHG-SGSESLYLAPGGSDDWIYDLGIKYSFTFEL 272
>1NSA-A nrPDB
Length = 395
Score = 261 bits (667), Expect = 4e-70, Method: Composition-based stats.
Identities = 53/283 (18%), Positives = 98/283 (34%), Gaps = 42/283 (14%)
Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
Y+ E +EA+ + V + +IG + G N+++L VG+ P
Sbjct: 97 KYNNWETIEAWTEQVTSKNPDLISRSAIGTTFDGDNIYLLKVGKPGSNK----PAIFMDC 152
Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
H E + + + V + G + +T +++ +++P +N DG+ + +
Sbjct: 153 GFHAREWISQAFCQWFVRDAVRTYGYEAHMTEFLDNLDFYVLPVLNIDGYIYTWTKNRMW 212
Query: 141 SIGREN-----YNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTE 181
R D NRNF + S P ET A+ +++
Sbjct: 213 RKTRSTNAGSSCTGTDPNRNFNAGWCTVGASVNPCNETYCGSAAESEKETKALADFIRNN 272
Query: 182 TFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKG 239
+ A +H + + YP+ Y L +D LA ++
Sbjct: 273 LSSIKAYLTIHSYSQMILYPYS---------YDYKLPENDAELNSLAKGAVKELASLY-- 321
Query: 240 DECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
++ G T + YP GG D+ Y + T EL
Sbjct: 322 ---GTSYSYGPGST---TIYPAAGGSDDWAYNQGIKYSFTFEL 358
>4UIB-A nrPDB
Length = 307
Score = 260 bits (665), Expect = 6e-70, Method: Composition-based stats.
Identities = 54/283 (19%), Positives = 95/283 (33%), Gaps = 42/283 (14%)
Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
Y+ E +EA+ K V + +IG + G N+++L VG+ P
Sbjct: 8 KYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKP----GPNKPAIFMDC 63
Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140
+H E + + V + G + +T +N +++P +N DG+ + +
Sbjct: 64 GIHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMW 123
Query: 141 SIGRE-----NYNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTE 181
R D NRNF + S P ET A+ +++
Sbjct: 124 RKTRSTNAGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNN 183
Query: 182 TFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKG 239
+ A ++H + YP+ Y L ++ LA +
Sbjct: 184 LSSIKAYLSIHSYSQHIVYPYS---------YDYKLPENNAELNNLAKAAVKELATLY-- 232
Query: 240 DECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
K + G T + Y GG D+ Y + T EL
Sbjct: 233 ---GTKYTYGPGAT---TLYLAPGGGDDWAYDQGIKYSFTFEL 269
>2BOA-A nrPDB
Length = 404
Score = 250 bits (637), Expect = 1e-66, Method: Composition-based stats.
Identities = 58/287 (20%), Positives = 104/287 (36%), Gaps = 43/287 (14%)
Query: 19 DFNYHRQEGMEAF---LKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75
+FNY +EA + +A ++ + IG S + R ++VL + P
Sbjct: 100 NFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFST---GKGVRRPA 156
Query: 76 FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135
A +H E + + + +V+ +DP IT+++ I ++P NPDG+ +
Sbjct: 157 VWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQT 216
Query: 136 PDCYYSIGR-----ENYNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMK 176
+ + R + D NRN+ +F S P E +V+
Sbjct: 217 QNRLWRKTRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVD 276
Query: 177 WLKTET-FVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPN 235
+++ F +LH + + YP+ YS PD + +A A +
Sbjct: 277 FIQKHGNFKGFIDLHSYSQLLMYPYG---------YSVKKAPDAEELDKVARLAAKALAS 327
Query: 236 MKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
+ + T + YP G D+ Y F T EL
Sbjct: 328 V-----SGTEYQVGPTCT---TVYPASGSSIDWAYDNGIKFAFTFEL 366
>4BD9-A nrPDB
Length = 310
Score = 248 bits (633), Expect = 3e-66, Method: Composition-based stats.
Identities = 58/287 (20%), Positives = 104/287 (36%), Gaps = 43/287 (14%)
Query: 19 DFNYHRQEGMEAF---LKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75
+FNY +EA + +A ++ + IG S + R ++VL + P
Sbjct: 6 NFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFST---GKGVRRPA 62
Query: 76 FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135
A +H E + + + +V+ +DP IT+++ I ++P NPDG+ +
Sbjct: 63 VWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQT 122
Query: 136 PDCYYSIGR-----ENYNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMK 176
+ + R + D NRN+ +F S P E +V+
Sbjct: 123 QNRLWRKTRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVD 182
Query: 177 WLKTET-FVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPN 235
+++ F +LH + + YP+ YS PD + +A A +
Sbjct: 183 FIQKHGNFKGFIDLHSYSQLLMYPYG---------YSVKKAPDAEELDKVARLAAKALAS 233
Query: 236 MKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
+ + T + YP G D+ Y F T EL
Sbjct: 234 V-----SGTEYQVGPTCT---TVYPASGSSIDWAYDNGIKFAFTFEL 272
>3V7Z-A nrPDB
Length = 326
Score = 242 bits (618), Expect = 2e-64, Method: Composition-based stats.
Identities = 78/327 (23%), Positives = 129/327 (39%), Gaps = 50/327 (15%)
Query: 17 ALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEF 76
+ D YH M + TVA NY ++ SIGKS +GR LW + + PE
Sbjct: 4 SYDSGYHNYNEMVNKINTVASNYPNIVKKFSIGKSYEGRELWAVKISDNVGTDE-NEPEV 62
Query: 77 KYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKP 136
Y A H E + E+ L+ +D + D ITNL+N+ I+I+ ++NPDG E
Sbjct: 63 LYTALHHAREHLTVEMALYTLDLFTQNYNLDSRITNLVNNREIYIVFNINPDGGEYDISS 122
Query: 137 DCY--YSIGR-----ENYNQYDLNRNF---------------PDAFEYNNVSRQPETVAV 174
Y + R +Y DLNRN+ + + + PET A+
Sbjct: 123 GSYKSWRKNRQPNSGSSYVGTDLNRNYGYKWGCCGGSSGSPSSETYRGRSAFSAPETAAM 182
Query: 175 MKWLKTETFVLSANLHGGALVASYPFDNGV-QATGALYS---RSLTPDD-DVFQYLAHTY 229
++ + V+ L+ + + + G Y+ +T DD +VF+ +A+T
Sbjct: 183 RDFINSR--VVGGKQQIKTLITFHTYSELILYPYGYTYTDVPSDMTQDDFNVFKTMANTM 240
Query: 230 ASRNPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCK--- 286
A N + Y G M D+ Y + F T E+
Sbjct: 241 AQTNGYTPQ---------------QASDLYITDGDMTDWAYGQHKIFAFTFEMYPTSYNP 285
Query: 287 --YPREEKLPSFWNNNKASLIEYIKQV 311
YP +E + + NK +++ ++
Sbjct: 286 GFYPPDEVIGRETSRNKEAVLYVAEKA 312
>1AYE-A nrPDB
Length = 401
Score = 238 bits (608), Expect = 3e-63, Method: Composition-based stats.
Identities = 63/314 (20%), Positives = 110/314 (35%), Gaps = 51/314 (16%)
Query: 18 LDFN-YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEF 76
+F YH E + + + + + +IG S + R + VL P
Sbjct: 100 FNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD-----KPAI 154
Query: 77 KYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKP 136
A +H E V + L + +V+ GKDP IT+++++ I ++P NPDG+ +
Sbjct: 155 WLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTK 214
Query: 137 DCYYSIGREN-----YNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKW 177
+ + R D NRN+ F S P E +++ +
Sbjct: 215 NRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDF 274
Query: 178 LKTETFV-LSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNM 236
+K+ V LH + + +P+ Y + D D +A A ++
Sbjct: 275 IKSHGKVKAFIILHSYSQLLMFPYG---------YKCTKLDDFDELSEVAQKAAQSLRSL 325
Query: 237 KKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCC-KY----PREE 291
K + Y GG D++Y + + EL +Y P +
Sbjct: 326 H-----GTKYKVGPICS---VIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQ 377
Query: 292 KLP---SFWNNNKA 302
LP W KA
Sbjct: 378 ILPTAEETWLGLKA 391
>1DTD-A nrPDB
Length = 303
Score = 237 bits (604), Expect = 9e-63, Method: Composition-based stats.
Identities = 63/315 (20%), Positives = 109/315 (34%), Gaps = 52/315 (16%)
Query: 18 LDFN-YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEF 76
+F YH E + + + + + +IG S + R + VL P
Sbjct: 1 FNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD-----KPAI 55
Query: 77 KYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKP 136
A +H E V + L + +V+ GKDP IT+++++ I ++P NPDG+ +
Sbjct: 56 WLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTK 115
Query: 137 DCYYSIGREN------YNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMK 176
+ + R D NRN+ F S P E +++
Sbjct: 116 NRMWRKTRSKVSAGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVD 175
Query: 177 WLKTETFV-LSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPN 235
++K+ V LH + + +P+ Y + D D +A A
Sbjct: 176 FIKSHGKVKAFIILHSYSQLLMFPYG---------YKCTKLDDFDELSEVAQKAAQSLSR 226
Query: 236 MKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCC-KY----PRE 290
+ K + Y GG D++Y + + EL +Y P
Sbjct: 227 LH-----GTKYKVGPICS---VIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPAR 278
Query: 291 EKLP---SFWNNNKA 302
+ LP W KA
Sbjct: 279 QILPTAEETWLGLKA 293
>3D68-A nrPDB
Length = 424
Score = 235 bits (598), Expect = 5e-62, Method: Composition-based stats.
Identities = 55/289 (19%), Positives = 104/289 (35%), Gaps = 41/289 (14%)
Query: 16 AALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75
A+ YH + ++++ + + + + IG S + L+VL V + +
Sbjct: 118 ASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVS---GKEQTAKNA 174
Query: 76 FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135
+H E + L I ++ G + TNL+ ++MP +N DG++ K
Sbjct: 175 IWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWK 234
Query: 136 PDCYYSIGRENYN-----QYDLNRNF---------------PDAFEYNNVSRQPETVAVM 175
+ + R Y DLNRNF + + +PE AV
Sbjct: 235 KNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVA 294
Query: 176 KWLKTETFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRN 233
+L+ + A ++H + +P+ Y+RS + D + +A
Sbjct: 295 SFLRRNINQIKAYISMHSYSQHIVFPYS---------YTRSKSKDHEELSLVASEAVRAI 345
Query: 234 PNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
+ K + + G + Y GG D+ Y + T+EL
Sbjct: 346 EKISKN------IRYTYG-QGSETLYLAPGGGDDWIYDLGIKYSFTIEL 387
>3LMS-A nrPDB
Length = 309
Score = 233 bits (594), Expect = 1e-61, Method: Composition-based stats.
Identities = 55/289 (19%), Positives = 103/289 (35%), Gaps = 41/289 (14%)
Query: 16 AALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75
A+ YH + ++++ + + + + IG S + L+VL V + +
Sbjct: 3 ASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVS---GKEQAAKNA 59
Query: 76 FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135
+H E + L I ++ G + TNL+ ++MP +N DG++ K
Sbjct: 60 IWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWK 119
Query: 136 PDCYYSIGRENYN-----QYDLNRNF---------------PDAFEYNNVSRQPETVAVM 175
+ + R Y DLNRNF + + +PE AV
Sbjct: 120 KNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVA 179
Query: 176 KWLKTETFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRN 233
+L+ + A ++H + +P+ Y+RS + D + +A
Sbjct: 180 SFLRRNINQIKAYISMHSYSQHIVFPYS---------YTRSKSKDHEELSLVASEAVRAI 230
Query: 234 PNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
K + +G + Y GG D+ Y + T+EL
Sbjct: 231 EKTSKNT------RYTHGH-GSETLYLAPGGGDDWIYDLGIKYSFTIEL 272
>3KGQ-A nrPDB
Length = 309
Score = 223 bits (567), Expect = 2e-58, Method: Composition-based stats.
Identities = 51/281 (18%), Positives = 95/281 (33%), Gaps = 41/281 (14%)
Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
YH + + F+ + + + IG+S +GR ++VL P
Sbjct: 12 YHTLDEIYDFMDLLVAEHPQLVSKLQIGRSYEGRPIYVLKFSTGGSNR----PAIWIDLG 67
Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
+H E + + + G+DP T +++S I + NPDGF + +
Sbjct: 68 IHSREWITQATGVWFAKKFTEDYGQDPSFTAILDSMDIFLEIVTNPDGFAFTHSQNRLWR 127
Query: 142 IGR-----ENYNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTET 182
R D NRN+ F S P E +++ ++K
Sbjct: 128 KTRSVTSSSLCVGVDANRNWDAGFGKAGASSSPCSETYHGKYANSEVEVKSIVDFVKDHG 187
Query: 183 -FVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDE 241
F ++H + + YP+ Y+ PD +A + ++
Sbjct: 188 NFKAFLSIHSYSQLLLYPYG---------YTTQSIPDKTELNQVAKSAVEALKSLY---- 234
Query: 242 CKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
+ + +T + Y GG D++Y + T EL
Sbjct: 235 -GTSYKYGSIIT---TIYQASGGSIDWSYNQGIKYSFTFEL 271
>5OM9-A nrPDB
Length = 419
Score = 215 bits (546), Expect = 5e-56, Method: Composition-based stats.
Identities = 51/281 (18%), Positives = 94/281 (33%), Gaps = 41/281 (14%)
Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
YH E + FL + + IG + +GR ++VL P
Sbjct: 122 YHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTG----GSKRPAIWIDTG 177
Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
+H E V + + + G+D T ++++ I + NPDGF + +
Sbjct: 178 IHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWR 237
Query: 142 IGREN-----YNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTET 182
R + D NRN+ F + S P E +++ ++K
Sbjct: 238 KTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHG 297
Query: 183 FV-LSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDE 241
+ ++H + + YP+ Y PD D L+ + ++
Sbjct: 298 NIKAFISIHSYSQLLMYPYG---------YKTEPVPDQDELDQLSKAAVTALASLY---- 344
Query: 242 CKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
K N+ + + + Y G D+ Y + T EL
Sbjct: 345 -GTKFNYGSII---KAIYQASGSTIDWTYSQGIKYSFTFEL 381
>4UEE-A nrPDB
Length = 309
Score = 212 bits (539), Expect = 3e-55, Method: Composition-based stats.
Identities = 51/281 (18%), Positives = 94/281 (33%), Gaps = 41/281 (14%)
Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
YH E + FL + + IG + +GR ++VL P
Sbjct: 12 YHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTG----GSKRPAIWIDTG 67
Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
+H E V + + + G+D T ++++ I + NPDGF + +
Sbjct: 68 IHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWR 127
Query: 142 IGREN-----YNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTET 182
R + D NRN+ F + S P E +++ ++K
Sbjct: 128 KTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHG 187
Query: 183 FV-LSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDE 241
+ ++H + + YP+ Y PD D L+ + ++
Sbjct: 188 NIKAFISIHSYSQLLMYPYG---------YKTEPVPDQDELDQLSKAAVTALASLY---- 234
Query: 242 CKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
K N+ + + + Y G D+ Y + T EL
Sbjct: 235 -GTKFNYGSII---KAIYQASGSTIDWTYSQGIKYSFTFEL 271
>1PCA-A nrPDB
Length = 403
Score = 211 bits (538), Expect = 4e-55, Method: Composition-based stats.
Identities = 46/281 (16%), Positives = 96/281 (34%), Gaps = 41/281 (14%)
Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
YH E + F+ + + ++ IG+S +GR ++VL P +
Sbjct: 107 YHTLEEIYDFMDILVAEHPALVSKLQIGRSYEGRPIYVLKFSTGGSNR----PAIWIDSG 162
Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
+H E + + + + + G++ T +++S I + NP+GF + +
Sbjct: 163 IHSREWITQASGVWFAKKITENYGQNSSFTAILDSMDIFLEIVTNPNGFAFTHSDNRLWR 222
Query: 142 IGRENYN-----QYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTET 182
R + D NRN+ F S P E ++ ++K
Sbjct: 223 KTRSKASGSLCVGSDSNRNWDAGFGGAGASSSPCAETYHGKYPNSEVEVKSITDFVKNNG 282
Query: 183 FV-LSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDE 241
+ ++H + + YP+ Y D +A + + ++
Sbjct: 283 NIKAFISIHSYSQLLLYPYG---------YKTQSPADKSELNQIAKSAVAALKSLY---- 329
Query: 242 CKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
+ + +T Y GG+ D+ Y + + EL
Sbjct: 330 -GTSYKYGSIIT---VIYQASGGVIDWTYNQGIKYSFSFEL 366
>1JQG-A nrPDB
Length = 433
Score = 203 bits (515), Expect = 2e-52, Method: Composition-based stats.
Identities = 66/283 (23%), Positives = 103/283 (36%), Gaps = 44/283 (15%)
Query: 23 HRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANM 82
H E ++A+L+ +A+ + +V + GKS +GR++ L + P + +
Sbjct: 122 HSYEEVDAYLQELAKEFPNVVTVVEGGKSFEGRSIKYLRIST-TNFQDASKPVVMMQSLL 180
Query: 83 HGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSI 142
H E V L+ I LV D ++LIN+ I+P NPDG+ D Y+
Sbjct: 181 HCREWVTLPATLYAIHKLVI----DVTESDLINNIDWIILPVANPDGYVHTFGGDRYWRK 236
Query: 143 GRENYN-------QYDLNRNF-------------PDAFEYNNVSRQPETVAVMKWL--KT 180
R DLNRNF D F + +PE+ + +
Sbjct: 237 NRATGYMAGNLCMGVDLNRNFGMNWGTASSSSVCSDTFHGRSAFSEPESSVIRDIIAEHR 296
Query: 181 ETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD 240
L ++H + Y + NGV + AL + A +K
Sbjct: 297 NRMALYLDIHSFGSMILYGYGNGVLPSNAL----------QLHLIGVQMAQAIDRVKWSS 346
Query: 241 ECKNKMNFPNGVTNGYS-WYPLQGGMQDYNYIWAQCFEITLEL 282
K+ + V N + Y GG DY A F T EL
Sbjct: 347 N-KDYI-----VGNIFHVLYAASGGASDYAMQAAAPFSYTYEL 383
>5MRV-A nrPDB
Length = 355
Score = 197 bits (501), Expect = 7e-51, Method: Composition-based stats.
Identities = 43/290 (14%), Positives = 97/290 (33%), Gaps = 42/290 (14%)
Query: 15 VAALDFN-YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGI 73
+ +N YH + +++ +++ Y V H +G + + ++ L + +
Sbjct: 48 LETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPIYYLKISQPSGN---PK 104
Query: 74 PEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAV 133
+H E + + ++ + + I L+ + +++P +N DG+
Sbjct: 105 KIIWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSRIRKLLRNLDFYVLPVLNIDGYIYT 164
Query: 134 KKPDCYYSIGRENYN-----QYDLNRNFPDAFEYNNVSRQ--------------PETVAV 174
D + R +N DLNRNF ++ SR PET AV
Sbjct: 165 WTTDRLWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAV 224
Query: 175 MKWLKTETFVL--SANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASR 232
+++++ + +H + P+ Y+++ + + + A+
Sbjct: 225 ASFIESKKDDILCFLTMHSYGQLILTPYG---------YTKNKSSNHPEMIQVGQKAANA 275
Query: 233 NPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
++ Y G +D+ F T EL
Sbjct: 276 LKAKY-----GTNYRVG---SSADILYASSGSSRDWARDIGIPFSYTFEL 317
>3K2K-A nrPDB
Length = 403
Score = 175 bits (443), Expect = 3e-44, Method: Composition-based stats.
Identities = 57/293 (19%), Positives = 107/293 (36%), Gaps = 42/293 (14%)
Query: 20 FNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79
F + +E FL V Q + +G++V+GR + ++V+G P E + +
Sbjct: 130 FEPYSEERHSEFLGAVQQM--PQASVVELGRTVEGRPMSLVVLGT-PDEAGAAKKKVWII 186
Query: 80 ANMHGDETVGRELLLHLIDYLVTSD--GKDPEITNLINSTRIHIMPSMNPDGFEAVKKPD 137
A H E++ + L+ LV DP L + +I+P+MNPDG
Sbjct: 187 ARQHPGESMAEWFIEGLVKRLVGWGDWSGDPVARKLYDHATFYIVPNMNPDG-------- 238
Query: 138 CYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVAS 197
+ R N +LNR + + R PE + V + L ++HG
Sbjct: 239 SVHGNLRTNAAGANLNREW----MEPDAERSPEVLVVRDAIHAIGCDLFFDIHG------ 288
Query: 198 YPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYS 257
+ + P Q + + A + + + +++ +P G +
Sbjct: 289 ----DEDLPYVFAAGSEMLPGFTEQQRVEQS-AFIDSFKRASPDFQDEHGYPPGKYREDA 343
Query: 258 WYPLQGGMQDYNYIWAQ--CFEITLELSCCKYPREEKLPSF---WNNNKASLI 305
+ YI + C +TLE+ + LP WN +++ +
Sbjct: 344 FKLASK------YIGHRFGCLSLTLEM---PFKDNANLPDEHIGWNGARSASL 387
>1CPB-B nrPDB
Length = 217
Score = 171 bits (432), Expect = 7e-43, Method: Composition-based stats.
Identities = 36/197 (18%), Positives = 67/197 (34%), Gaps = 38/197 (19%)
Query: 107 DPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGREN-----YNQYDLNRNFPDAFE 161
+ +T ++ +++P +N DG+ + + R DLNRNF +
Sbjct: 1 EIHMTEFLDKLDFYVLPVVNIDGYIYTWTTNRMWRKTRSTRAGSSCTGTDLNRNFDAGWC 60
Query: 162 YNNVSRQP--------------ETVAVMKWLKTETFVLSA--NLHGGALVASYPFDNGVQ 205
S P E+ AV +++ + A +H + + YP+
Sbjct: 61 SIGASNNPCSETYCGSAAESEKESKAVADFIRNHLSSIKAYLTIHSYSQMMLYPYS---- 116
Query: 206 ATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGM 265
Y L ++ LA + ++ ++ G T + YP GG
Sbjct: 117 -----YDYKLPKNNVELNTLAKGAVKKLASLH-----GTTYSYGPGAT---TIYPASGGS 163
Query: 266 QDYNYIWAQCFEITLEL 282
D+ Y + T EL
Sbjct: 164 DDWAYDQGIKYSFTFEL 180
>4B6Z-A nrPDB
Length = 405
Score = 166 bits (420), Expect = 2e-41, Method: Composition-based stats.
Identities = 42/174 (24%), Positives = 71/174 (40%), Gaps = 17/174 (9%)
Query: 20 FNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79
F + +E AFL V Q + +G++V+GR + +L +G P+ + +
Sbjct: 132 FEPYSEERHAAFLGAVQQL--PQASVVELGRTVEGRPMSLLTLGT-PETDGAPKKKVWII 188
Query: 80 ANMHGDETVGRELLLHLIDYLVTSD--GKDPEITNLINSTRIHIMPSMNPDGFEAVKKPD 137
A H E++ + L+ L DP L + HI+P+MNPDG
Sbjct: 189 ARQHPGESMAEWFVEGLVKRLAGWGDWAGDPVARKLYDRVTFHIVPNMNPDG-------- 240
Query: 138 CYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHG 191
+ R N +LNR + + R PE +AV + + ++HG
Sbjct: 241 SVHGNLRTNAAGANLNREWMA----PDAERSPEVLAVRDAIHAIGCDMFFDIHG 290
>2C1C-A nrPDB
Length = 312
Score = 165 bits (418), Expect = 3e-41, Method: Composition-based stats.
Identities = 54/290 (18%), Positives = 97/290 (33%), Gaps = 43/290 (14%)
Query: 17 ALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEF 76
D NY E ++ +L + + Y V + + +S +GR + + + E P
Sbjct: 2 PYD-NYQELEVIDEYLDYIGEKYPDVATVVNAAESFEGRPIKYIKISTTNFEDE-NKPVI 59
Query: 77 KYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKP 136
+H E + + I LV D +L+ ++P +NPDG++
Sbjct: 60 FIDGGIHAREWISPPSVTWAIHKLVE----DVTENDLLEKFDWILLPVVNPDGYKYTFTN 115
Query: 137 DCYYSIGRENYN--------QYDLNRNFP--------------DAFEYNNVSRQPETVAV 174
+ ++ R N D NRNF D + + + ET V
Sbjct: 116 ERFWRKTRSTNNNPLSQICRGADGNRNFDFVWNSIGTSNSPCSDIYAGTSAFSEVETRVV 175
Query: 175 MKWLKTE--TFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASR 232
L L +H + YP+ + G+L +L HT
Sbjct: 176 RDILHEHLARMALYLTMHSFGSMILYPWGHD----GSLSQNALG---------LHTVGVA 222
Query: 233 NPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282
++ + + N + G + Y + G +DY + T EL
Sbjct: 223 MASVIQSNALPNFPPYTVGNSALVIGYYIAGSSEDYAHSIGVPLSYTYEL 272
>4A39-A nrPDB
Length = 388
Score = 152 bits (385), Expect = 2e-37, Method: Composition-based stats.
Identities = 43/172 (25%), Positives = 73/172 (42%), Gaps = 20/172 (11%)
Query: 20 FNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79
F + +E ++ ++G SV+GR++ +L V R P H + +
Sbjct: 123 FEPYSRERHARLVERALGIEG--VERLAVGTSVQGRDIELLRVRRHPDSHL----KLWVI 176
Query: 80 ANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCY 139
A H E + + LI+ L D D E+ L+ ++++P+MNPDG +
Sbjct: 177 AQQHPGEHMAEWFMEGLIERLQRPD--DTEMQRLLEKADLYLVPNMNPDG--------AF 226
Query: 140 YSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHG 191
+ R N DLNR A+ + R PE V + +K L ++HG
Sbjct: 227 HGNLRTNAAGQDLNR----AWLEPSAERSPEVWFVQQEMKRHGVDLFLDIHG 274
>3L2N-A nrPDB
Length = 395
Score = 121 bits (303), Expect = 6e-28, Method: Composition-based stats.
Identities = 37/177 (20%), Positives = 69/177 (38%), Gaps = 20/177 (11%)
Query: 15 VAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIP 74
+ F + E + V + + +G ++ GR++ ++ VG
Sbjct: 123 IQIAYFTPYSYERHLDLISAVQ-LHP-LVSTEHLGLTLDGRDMTLVKVGD----DDPSKK 176
Query: 75 EFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVK 134
A H ET+ L+ L++ L+ +D P L++ +I+P+MNPDG
Sbjct: 177 SIWITARQHPGETMAEWLVEGLLNQLLDNDC--PTSKALLDKANFYIVPNMNPDG----- 229
Query: 135 KPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHG 191
R N +LNR + + ++ R PE V+ + L ++HG
Sbjct: 230 ---SVRGHLRTNAVGANLNREW----QTPSLERSPEVYYVVNKMHETGVDLFYDVHG 279
>1CPB-A nrPDB
Length = 82
Score = 92.9 bits (229), Expect = 3e-19, Method: Composition-based stats.
Identities = 15/79 (18%), Positives = 28/79 (35%), Gaps = 4/79 (5%)
Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80
Y+ E +EA+ + VA + +IG + G +++L VG+ P
Sbjct: 8 KYNNWETIEAWTEQVASENPDLISRSAIGTTFLGNTIYLLKVGKPGSNK----PAVFMDC 63
Query: 81 NMHGDETVGRELLLHLIDY 99
H E + +
Sbjct: 64 GFHAREWISPAFCQWFVRE 82
>5AQ0-A nrPDB
Length = 82
Score = 90.2 bits (222), Expect = 2e-18, Method: Composition-based stats.
Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 4/69 (5%)
Query: 314 GVKGQVFDQ-NGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDP- 371
GVKG V D G+ L N + V H T ++G++Y LL+PG+Y + V + G+ P
Sbjct: 2 GVKGFVKDSITGSGLENATISVAGINH--NITTGRFGDFYRLLVPGTYNLTVVLTGYMPL 59
Query: 372 HITKVIIPE 380
+T V++ E
Sbjct: 60 TVTNVVVKE 68
>2QVP-A nrPDB
Length = 275
Score = 50.9 bits (120), Expect = 1e-06, Method: Composition-based stats.
Identities = 28/143 (19%), Positives = 47/143 (32%), Gaps = 28/143 (19%)
Query: 43 THLHSIGKSVKGR----NLWVLVVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLID 98
T +G + G+ L++L + G+P A HG+E+ G LLH +
Sbjct: 35 TERLGLGSKILGQAGHHPLYLLQ----SPGQKAGLPNLLISAGFHGEESAGPWGLLHFLS 90
Query: 99 YLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNF-- 156
L L + ++P +NP GF R N + NR F
Sbjct: 91 QLDG---------ELFKRVNLSVLPLVNPTGFAKGH---------RFNELGENPNRGFFI 132
Query: 157 PDAFEYNNVSRQPETVAVMKWLK 179
+ E +++
Sbjct: 133 ENGKAKPGADTSAEGRILLEHAH 155
>3B2Y-A nrPDB
Length = 275
Score = 48.6 bits (114), Expect = 5e-06, Method: Composition-based stats.
Identities = 46/283 (16%), Positives = 86/283 (30%), Gaps = 37/283 (13%)
Query: 26 EGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANMHGD 85
++AF +A+ + + + SV + + R +P + HG+
Sbjct: 23 NDIDAFYAQLAEEVNRLGLKKNTLGSVDSFAINLYQ----SASQRSDLPSLLISSGFHGE 78
Query: 86 ETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRE 145
E G +LH + L L + ++P +NP GF+A + + +
Sbjct: 79 EAAGPWGMLHFLRGLQ---------PALFERVNLSLLPLVNPTGFKAGHRFNRF------ 123
Query: 146 NYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQ 205
+ NR F T K L +L A G L ++ +
Sbjct: 124 ---GENPNRGFTLENGKPT--PNEHTSLEGKLLLEHAQLLCAASRDGILTC---HEDVLM 175
Query: 206 ATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGM 265
+YS T F K + P VT+G +
Sbjct: 176 NETYVYSFEPTQTPGRFSLGLR---DALGQYFKLAKDGFIDECP--VTDGVIFNHFDTSF 230
Query: 266 QDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYI 308
+ + +C + P +E N A++ ++I
Sbjct: 231 EAFLVRSGAKLA-----ACSETPGQEDFDRRVQANSAAMGQFI 268
>5HXD-A nrPDB
Length = 237
Score = 47.1 bits (110), Expect = 2e-05, Method: Composition-based stats.
Identities = 34/166 (20%), Positives = 51/166 (30%), Gaps = 49/166 (29%)
Query: 47 SIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGK 106
G+S+ G L +E + +A HGDE L + L S +
Sbjct: 19 HYGRSLLGAPLIWFPAPAASRESGL------ILAGTHGDENSSVVTLSCALRTLTPSLRR 72
Query: 107 DPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDA------- 159
H++ +NPDG + R N N DLNRNFP A
Sbjct: 73 H------------HVVLCVNPDGCQLG---------LRANANGVDLNRNFPAANWKEGET 111
Query: 160 ---------------FEYNNVSRQPETVAVMKWLKTETFVLSANLH 190
+ +PET A+ + + + H
Sbjct: 112 VYRWNSAAEERDVVLLTGDKPGSEPETQALCQLIHRIQPAWVVSFH 157
>3IEH-A nrPDB
Length = 276
Score = 45.1 bits (105), Expect = 6e-05, Method: Composition-based stats.
Identities = 21/87 (24%), Positives = 33/87 (37%), Gaps = 18/87 (20%)
Query: 70 RIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDG 129
+ G+P A HG+E+ G LLH + +L + ++P +NP G
Sbjct: 63 KSGLPSLLISAGFHGEESAGPWGLLHFLSEAS---------ADLFERVNLSLLPLVNPTG 113
Query: 130 FEAVKKPDCYYSIGRENYNQYDLNRNF 156
F + R N + NR F
Sbjct: 114 F------SRGH---RFNKYGENPNRGF 131
>4OKO-A nrPDB
Length = 312
Score = 40.9 bits (94), Expect = 0.001, Method: Composition-based stats.
Identities = 34/168 (20%), Positives = 60/168 (35%), Gaps = 31/168 (18%)
Query: 25 QEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANMHG 84
Q+ E + + ++ + + V L+ L K P +HG
Sbjct: 33 QQEAEKKILALVSDF-DIDEYGQLDYPVGSYKLYALK----TKNWDASKPYVLVTGGVHG 87
Query: 85 DETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGR 144
ET G + + +D I I+P ++P G+E +I R
Sbjct: 88 YETSGVQGAISFAQTRALEFARD---------YNIVILPCLSPWGYE---------TINR 129
Query: 145 ENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTET--FVLSANLH 190
N N D NR+F + + E V MK++ + F++ +LH
Sbjct: 130 WNPNALDPNRSF---YLESGCQ---EAVLAMKYVFSLGVEFLMHIDLH 171
>2QJ8-A nrPDB
Length = 332
Score = 37.0 bits (84), Expect = 0.014, Method: Composition-based stats.
Identities = 32/166 (19%), Positives = 48/166 (28%), Gaps = 37/166 (22%)
Query: 53 KGRNLWVLVVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITN 112
KG + L + F G P HG+E G L LV +
Sbjct: 26 KGADCEALSLPVFSCNRGEG-PSLLITGGNHGNELQGPI----LARRLVKWLPEAQRCG- 79
Query: 113 LINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRENYN-QYDLNRNFPDAFEYNNVSRQPET 171
RI I+P +NP + R +LNR FP + + R
Sbjct: 80 -----RIIIVPEINP---------LAVQAWTRNTPIDGKNLNRVFPGRSDGSVSER---- 121
Query: 172 VAVMKWLKTET---FVLSANLHGGA-------LVASYPFDNGVQAT 207
+ + +LH + S+P + Q T
Sbjct: 122 --IADAISRLLLPVVDTVLDLHSFGPTWDCAPSIISHPIADIDQMT 165
>4RWR-A nrPDB
Length = 331
Score = 36.3 bits (82), Expect = 0.025, Method: Composition-based stats.
Identities = 21/108 (19%), Positives = 35/108 (32%), Gaps = 6/108 (5%)
Query: 287 YPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTN 346
Y +E+L W NN + ++ I++ GQV G P+ RT
Sbjct: 124 YKSKEELKKQWGNNYENNLKKIEEAVSKTAGQVLTYEGKPISASFFSTS------NGRTE 177
Query: 347 KYGEYYLLLLPGSYIINVTVPGHDPHITKVIIPEKSQNFSALKKDILL 394
+Y+ P ++ P T I + L +L
Sbjct: 178 NAADYWGNDYPYLKSVDSPWDQASPKFTSEQIFTVADFQKRLGVKVLA 225
>4AXV-A nrPDB
Length = 243
Score = 35.9 bits (81), Expect = 0.035, Method: Composition-based stats.
Identities = 32/116 (27%), Positives = 37/116 (31%), Gaps = 27/116 (23%)
Query: 42 VTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLV 101
+ S GKSV G L + +A HGDET L + L
Sbjct: 20 LITPTSYGKSVLGAPLLYFPAQVESNSRGL------ILAGTHGDETASIAGLSCALRSLP 73
Query: 102 TSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFP 157
K I SMNPD + R N NQ DLNR FP
Sbjct: 74 AECLKHDVIL------------SMNPDANQLG---------TRANANQVDLNRAFP 108
>2OKL-A nrPDB
Length = 185
Score = 33.6 bits (75), Expect = 0.20, Method: Composition-based stats.
Identities = 15/72 (20%), Positives = 27/72 (37%), Gaps = 7/72 (9%)
Query: 319 VFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVII 378
V D +G + + + H + GE G ++ VPG+ P T++ +
Sbjct: 78 VTDADGTLYSHALFNPKIISHSVERTYLQGGE-------GCLSVDREVPGYVPRYTRITV 130
Query: 379 PEKSQNFSALKK 390
S N +K
Sbjct: 131 KATSINGEEVKL 142
>5OCR-A nrPDB
Length = 286
Score = 32.0 bits (71), Expect = 0.53, Method: Composition-based stats.
Identities = 27/188 (14%), Positives = 55/188 (29%), Gaps = 29/188 (15%)
Query: 4 PCLWLGLLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGR--NLWVLV 61
P WL + D++ E + + + V +G +++ +
Sbjct: 117 PSFWL------YSDFDYSVANGETVYSEIDVVELQQFDW---------YEGHQDDIYDMD 161
Query: 62 VGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHI 121
+ G M+ E + + G + +I ++
Sbjct: 162 LNLHAVVKENGQ-GVWKRPKMYPQEQLNKWRAPWDPSKDFHIYGCEVNQNEII----WYV 216
Query: 122 MPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVA-VMKWLKT 180
DG E +KP+ Y+ L + F F+ N + PET A + L
Sbjct: 217 ------DGVEVARKPNKYWHRPMNVTLSLGLRKPFVKFFDNKNNAINPETDAKAREKLSD 270
Query: 181 ETFVLSAN 188
+ +
Sbjct: 271 IPTSMYVD 278
>5JBE-A nrPDB
Length = 854
Score = 31.3 bits (69), Expect = 0.79, Method: Composition-based stats.
Identities = 21/162 (12%), Positives = 48/162 (29%), Gaps = 7/162 (4%)
Query: 124 SMNPDGFEAVKKPDCYYSIGRENYNQYD---LNRNFPDAFEYNNVSRQPETVAVMKWLKT 180
+++ D V G +Y + +NR + NN PE + +
Sbjct: 160 TIDSDQVIFVNNNSKDPRKGNTSYADSNYRLMNRTINNQAGNNNSDNSPELLVGNDIDNS 219
Query: 181 ETFVLSANLHGGALVASY----PFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNM 236
V + NL+ + +Y ++ G + D DV +
Sbjct: 220 NPVVQAENLNWEYFLLNYGKLMGYNPDGNFDGFRVDAADNIDADVLDQMGQLMNDMYHTK 279
Query: 237 KKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEI 278
+ +++ G +G + + G + + +
Sbjct: 280 GNPQNANDHLSYNEGYHSGAAQMLNEKGNPQLYMDSGEFYTL 321
>5VOC-B nrPDB
Length = 278
Score = 30.9 bits (68), Expect = 1.3, Method: Composition-based stats.
Identities = 18/80 (22%), Positives = 25/80 (31%), Gaps = 16/80 (20%)
Query: 6 LWLGLLLPLV--AALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKG-------RN 56
LW LLLP+V AA+ E V +T +G+ +G R
Sbjct: 19 LWCCLLLPIVSSAAVSVAPTAAE-------KVPAECPELTRRCLLGEVFEGDKYESWLRP 71
Query: 57 LWVLVVGRFPKEHRIGIPEF 76
L + P I
Sbjct: 72 LVNVTGRDGPLSQLIRYRPV 91
>3A22-A nrPDB
Length = 614
Score = 30.5 bits (67), Expect = 1.5, Method: Composition-based stats.
Identities = 20/123 (16%), Positives = 37/123 (30%), Gaps = 23/123 (18%)
Query: 72 GIPEFKYVAN---MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSM--- 125
G P + N + + L + G P +T+L+++ + P+
Sbjct: 172 GRPLTLSICNWGYQNPWNWAAGQAPLWRTSTDIIYYGNQPSMTSLLSNFDQTLHPTAQHT 231
Query: 126 ----NP-------DGFEAVKKPDCYYSIGRENY---NQYDLNRNFPDAFEYNNVSRQPET 171
+P DGF A + DL + + + PE
Sbjct: 232 GYYNDPDMLMVGMDGFTAAQNRTHMNLWAISGAPLLAGNDLTTMTSETA---GILKNPEV 288
Query: 172 VAV 174
+AV
Sbjct: 289 IAV 291
>2AZQ-A nrPDB
Length = 311
Score = 29.7 bits (65), Expect = 2.7, Method: Composition-based stats.
Identities = 14/36 (38%), Positives = 17/36 (47%), Gaps = 3/36 (8%)
Query: 315 VKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGE 350
++GQVFD NG PL V D H T Y +
Sbjct: 135 LQGQVFDANGKPLAGATV---DLWHANTQGTYSYFD 167
>3ZHL-A nrPDB
Length = 127
Score = 29.3 bits (64), Expect = 3.2, Method: Composition-based stats.
Identities = 9/81 (11%), Positives = 24/81 (29%), Gaps = 11/81 (13%)
Query: 230 ASRNPNMKKGDECKNKMNFPNGVTNGYSWY---------PLQGGMQDYNYIWAQ--CFEI 278
+ +++ + + G +WY + ++ Y+ E
Sbjct: 31 SYAMGWVRQAPGKGPEWVSLISGSGGSTWYDDSVKGRFTISRDNSKNLLYLQMNSLRAED 90
Query: 279 TLELSCCKYPREEKLPSFWNN 299
T C ++ + P +W
Sbjct: 91 TAVYYCARHAPSTEAPDYWGQ 111
>4E79-A nrPDB
Length = 357
Score = 28.6 bits (62), Expect = 5.3, Method: Composition-based stats.
Identities = 17/81 (20%), Positives = 31/81 (38%), Gaps = 2/81 (2%)
Query: 299 NNKASLIEYIKQVHLGVKGQVFDQNGNPLPN-VIVEVQDRKHICPYRTNKYGEYYLLLLP 357
+K + HL VKG++ + N +E + H+ K+ + +
Sbjct: 2 GSKVQQYRLDELAHL-VKGELIGEGSLQFSNLASLENAEVNHLTFVNGEKHLDQAKVSRA 60
Query: 358 GSYIINVTVPGHDPHITKVII 378
G+YI+ + H P II
Sbjct: 61 GAYIVTAALKEHLPEKDNFII 81
>4M1U-A nrPDB
Length = 297
Score = 28.6 bits (62), Expect = 5.5, Method: Composition-based stats.
Identities = 7/56 (12%), Positives = 22/56 (39%)
Query: 327 LPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVIIPEKS 382
+ + V + ++ ++ + +PG +++T + +V E+S
Sbjct: 71 IEQNNLYVAGFVNTATNTFYRFSDFTHISVPGVTTVSMTTDSSYTTLQRVAALERS 126
>2HN1-A nrPDB
Length = 266
Score = 28.6 bits (62), Expect = 6.2, Method: Composition-based stats.
Identities = 17/109 (15%), Positives = 36/109 (33%), Gaps = 3/109 (2%)
Query: 50 KSVKGRNLWVLVVGRFPKEHRIGIPEFKYV-ANMHGDETVGRELLLHL-IDYLVTSDGKD 107
KSV+ + L V + + + +H DE++ ++ L I L D +
Sbjct: 42 KSVEFKELEVGELESVVRSALALNKKLWIDVVGVH-DESLIAKICEFLGIHPLAAEDILN 100
Query: 108 PEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNF 156
I H+ + + + D + ++N R +
Sbjct: 101 TAQRVKIEDYDDHLFLVLKILLYNETLEIDQLSLVLKKNLVATFEEREY 149
>1JQP-A nrPDB
Length = 438
Score = 27.8 bits (60), Expect = 9.4, Method: Composition-based stats.
Identities = 12/49 (24%), Positives = 20/49 (40%), Gaps = 1/49 (2%)
Query: 248 FPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSF 296
+ G G+ + QD+ + CF T + CK P+E L +
Sbjct: 269 YAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCK-PKENCLRYY 316
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
Posted date: Jan 3, 2023 9:05 PM
Number of letters in database: 10,336,785
Number of sequences in database: 36,641
Lambda K H
0.311 0.127 0.346
Lambda K H
0.267 0.0393 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,579,089
Number of Sequences: 36641
Number of extensions: 702915
Number of successful extensions: 2064
Number of sequences better than 10.0: 53
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 1812
Number of HSP's gapped (non-prelim): 105
length of query: 443
length of database: 10,336,785
effective HSP length: 100
effective length of query: 343
effective length of database: 6,672,685
effective search space: 2288730955
effective search space used: 2288730955
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.4 bits)
S2: 60 (27.8 bits)