BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P14384 (443 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1UWY-A nrPDB 888 0.0 1QMU-A nrPDB 365 e-101 3MN8-A nrPDB 323 6e-89 2NSM-A nrPDB 301 5e-82 3V7Z-A nrPDB 72 5e-13 4A39-A nrPDB 54 2e-07 1KWM-A nrPDB 49 4e-06 1ZLI-A nrPDB 49 5e-06 4BD9-A nrPDB 46 4e-05 2BOA-A nrPDB 45 5e-05 3OSL-A nrPDB 45 7e-05 4B6Z-A nrPDB 45 8e-05 3D4U-A nrPDB 44 1e-04 1DTD-A nrPDB 44 1e-04 1JQG-A nrPDB 44 2e-04 3K2K-A nrPDB 44 2e-04 1AYE-A nrPDB 43 2e-04 5AQ0-A nrPDB 41 0.001 4UIB-A nrPDB 40 0.002 3GLJ-A nrPDB 39 0.005 1NSA-A nrPDB 39 0.006 3KGQ-A nrPDB 36 0.027 3L2N-A nrPDB 36 0.032 3D68-A nrPDB 35 0.068 3LMS-A nrPDB 35 0.072 4UEE-A nrPDB 33 0.18 2QVP-A nrPDB 33 0.21 5MRV-A nrPDB 33 0.21 5OM9-A nrPDB 33 0.29 1PCA-A nrPDB 32 0.53 5HXD-A nrPDB 32 0.60 4GFJ-A nrPDB 31 0.86 5HM5-A nrPDB 31 0.97 3IEH-A nrPDB 31 1.0 2C1C-A nrPDB 30 2.2 6D97-A nrPDB 30 2.6 3B2Y-A nrPDB 29 3.2 3N5M-A nrPDB 28 6.5 1SEZ-A nrPDB 28 8.8 1YKN-B nrPDB 28 9.4 >1UWY-A nrPDB Length = 426 Score = 888 bits (2295), Expect = 0.0, Method: Compositional matrix adjust. Identities = 426/426 (100%), Positives = 426/426 (100%) Query: 18 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK Sbjct: 1 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 60 Query: 78 YVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPD 137 YVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPD Sbjct: 61 YVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPD 120 Query: 138 CYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVAS 197 CYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVAS Sbjct: 121 CYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVAS 180 Query: 198 YPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYS 257 YPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYS Sbjct: 181 YPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYS 240 Query: 258 WYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKG 317 WYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKG Sbjct: 241 WYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKG 300 Query: 318 QVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVI 377 QVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVI Sbjct: 301 QVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVI 360 Query: 378 IPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLPDHSAATKPSLFLFLVSL 437 IPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLPDHSAATKPSLFLFLVSL Sbjct: 361 IPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLPDHSAATKPSLFLFLVSL 420 Query: 438 LHIFFK 443 LHIFFK Sbjct: 421 LHIFFK 426 >1QMU-A nrPDB Length = 380 Score = 365 bits (937), Expect = e-101, Method: Compositional matrix adjust. Identities = 187/367 (50%), Positives = 247/367 (67%), Gaps = 10/367 (2%) Query: 15 VAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIP 74 V +DF +H ME FL+ A Y S+T L+S+GKSV+ R L+V+ + P H G P Sbjct: 3 VQPVDFRHHHFSDMEIFLRRYANEYPSITRLYSVGKSVELRELYVMEISDNPGIHEAGEP 62 Query: 75 EFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVK 134 EFKY+ NMHG+E VGRELLL+LI+YL + G DPE+T+L+ STRIHIMPSMNPDG+E + Sbjct: 63 EFKYIGNMHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVQSTRIHIMPSMNPDGYEKSQ 122 Query: 135 KPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGAL 194 + D ++GR N N YDLNRNFPD F QPET+AVM WLKT FVLSANLHGG+L Sbjct: 123 EGDRGGTVGRNNSNNYDLNRNFPDQFFQVTDPPQPETLAVMSWLKTYPFVLSANLHGGSL 182 Query: 195 VASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKN---KMNFPNG 251 V +YPFD+ Q A+YS+S PDD VFQ LA +Y+ N M +G CK+ FP+G Sbjct: 183 VVNYPFDDDEQGI-AIYSKS--PDDAVFQQLALSYSKENKKMYQGSPCKDLYPTEYFPHG 239 Query: 252 VTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQV 311 +TNG WY + GGMQD+NY+ CFE+T+EL C KYP+ E+LP +W N+ SL+++IKQV Sbjct: 240 ITNGAQWYNVPGGMQDWNYLNTNCFEVTIELGCVKYPKAEELPKYWEQNRRSLLQFIKQV 299 Query: 312 HLGVKGQVFDQ-NGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHD 370 H G+ G V D +G + N + V D H P T K G+Y+ LL+ G+Y + + G+D Sbjct: 300 HRGIWGFVLDATDGRGILNATISVADINH--PVTTYKDGDYWRLLVQGTYKVTASARGYD 357 Query: 371 PHITKVI 377 P +TK + Sbjct: 358 P-VTKTV 363 >3MN8-A nrPDB Length = 435 Score = 323 bits (829), Expect = 6e-89, Method: Compositional matrix adjust. Identities = 169/396 (42%), Positives = 246/396 (62%), Gaps = 21/396 (5%) Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80 +Y QE +E + + Y + +H +G+S++GRNL L + R + + P KY+A Sbjct: 39 HYASQEQLEDLFAGLEKAYPNQAKVHFLGRSLEGRNLLALQISRNTRSRNLLTPPVKYIA 98 Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140 NMHGDETVGR+LL+++ YL+ + + ++ L+NST I+++P+MNPDG+ ++ +C Sbjct: 99 NMHGDETVGRQLLVYMAQYLLGNHERISDLGQLVNSTDIYLVPTMNPDGYALSQEGNCES 158 Query: 141 ---SIGRENYNQYDLNRNFPDAFEYNNV------SRQPETVAVMKWLKTETFVLSANLHG 191 +GR N DLNR+FPD E ++V SRQPET A++ W+ ++ FVLSAN HG Sbjct: 159 LPNYVGRGNAANIDLNRDFPDRLEQSHVHQLRAQSRQPETAALVNWIVSKPFVLSANFHG 218 Query: 192 GALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNG 251 GA+VASYP+DN + A SLTPDD VF+ LAHTY+ +P M+KG+ C + +F G Sbjct: 219 GAVVASYPYDNSL-AHNECCEESLTPDDRVFKQLAHTYSDNHPIMRKGNNCND--SFSGG 275 Query: 252 VTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQV 311 +TNG WY L GGMQD+NY ++ CFE+T+ELSCCKYP LP W NKASL++ ++Q Sbjct: 276 ITNGAHWYELSGGMQDFNYAFSNCFELTIELSCCKYPAASTLPQEWQRNKASLLQLLRQA 335 Query: 312 HLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHD- 370 H+G+KG V D +G P+ + V V + P RT+K GEY+ LL PG Y ++ + G+ Sbjct: 336 HIGIKGLVTDASGFPIADANVYVAGLEEK-PMRTSKRGEYWRLLTPGLYSVHASAFGYQT 394 Query: 371 --PHITKVIIPEKSQNFSALKKDI-LLPFQGQLDSI 403 P +V + N AL+ D L P + D I Sbjct: 395 SAPQQVRVT----NDNQEALRLDFKLAPVETNFDGI 426 >2NSM-A nrPDB Length = 439 Score = 301 bits (770), Expect = 5e-82, Method: Compositional matrix adjust. Identities = 172/391 (43%), Positives = 232/391 (59%), Gaps = 38/391 (9%) Query: 18 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77 L F +HR + + L V +T ++SIG+SV+GR+L+VL P H PE K Sbjct: 2 LAFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVK 61 Query: 78 YVANMHGDETVGRELLLHLIDYLVTS-DGKDPEITNLINSTRIHIMPSMNPDGFE--AVK 134 YV NMHG+E +GREL+L L ++L ++ I LI TRIHI+PSMNPDG+E A + Sbjct: 62 YVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQ 121 Query: 135 KPDC-YYSIGRENYNQYDLNRNFPDAFEY-----------------NNVSRQ--PETVAV 174 P+ Y +GR N N DLNRNFPD Y +N Q PET AV Sbjct: 122 GPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLPDNWKSQVEPETRAV 181 Query: 175 MKWLKTETFVLSANLHGGALVASYPFD-------NGVQATGALYSRSLTPDDDVFQYLAH 227 ++W+ + FVLSANLHGGA+VA+YP+D GV+ T + + TPDD +FQ LA Sbjct: 182 IRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTAS----TPTPDDKLFQKLAK 237 Query: 228 TYASRNPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKY 287 Y+ + M +G C + FP+G+TNG SWY L GMQD+NY+ CFEITLELSC K+ Sbjct: 238 VYSYAHGWMFQGWNCGDY--FPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKF 295 Query: 288 PREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNK 347 P EE+L W NK +LI++++QVH G+KG V DQN N L N ++ V H + Sbjct: 296 PPEEELQREWLGNKEALIQFLEQVHQGIKGMVLDQNYNNLANAVISVSGINHDVT--SGD 353 Query: 348 YGEYYLLLLPGSYIINVTVPGHDPHITKVII 378 +G+Y+ LLLPG Y ++ T PG+DP V + Sbjct: 354 HGDYFRLLLPGIYTVSATAPGYDPETVTVTV 384 >3V7Z-A nrPDB Length = 326 Score = 72.0 bits (175), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 78/308 (25%), Positives = 122/308 (39%), Gaps = 65/308 (21%) Query: 17 ALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGI--- 73 + D YH M + TVA NY ++ SIGKS +GR LW + + +G Sbjct: 4 SYDSGYHNYNEMVNKINTVASNYPNIVKKFSIGKSYEGRELWAVKIS-----DNVGTDEN 58 Query: 74 -PEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEA 132 PE Y A H E + E+ L+ +D + D ITNL+N+ I+I+ ++NPDG E Sbjct: 59 EPEVLYTALHHAREHLTVEMALYTLDLFTQNYNLDSRITNLVNNREIYIVFNINPDGGEY 118 Query: 133 VKKPDCYYSIGR-------ENYNQYDLNRNF---------------PDAFEYNNVSRQPE 170 Y S + +Y DLNRN+ + + + PE Sbjct: 119 DISSGSYKSWRKNRQPNSGSSYVGTDLNRNYGYKWGCCGGSSGSPSSETYRGRSAFSAPE 178 Query: 171 TVAVMKWLKTETFVLSANLHGGALVASYPFDNGV-QATGALYS---RSLTPDD-DVFQYL 225 T A+ ++ + V+ L+ + + + G Y+ +T DD +VF+ + Sbjct: 179 TAAMRDFINSR--VVGGKQQIKTLITFHTYSELILYPYGYTYTDVPSDMTQDDFNVFKTM 236 Query: 226 AHTYASRNPNMKKGDECKNKMNFPNGVTNGYS------WYPLQGGMQDYNYIWAQCFEIT 279 A+T A TNGY+ Y G M D+ Y + F T Sbjct: 237 ANTMAQ---------------------TNGYTPQQASDLYITDGDMTDWAYGQHKIFAFT 275 Query: 280 LELSCCKY 287 E+ Y Sbjct: 276 FEMYPTSY 283 >4A39-A nrPDB Length = 388 Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 41/145 (28%), Positives = 67/145 (46%), Gaps = 18/145 (12%) Query: 47 SIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGK 106 ++G SV+GR++ +L V R P H + +A H E + + LI+ L D Sbjct: 148 AVGTSVQGRDIELLRVRRHPDSHL----KLWVIAQQHPGEHMAEWFMEGLIERLQRPD-- 201 Query: 107 DPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVS 166 D E+ L+ ++++P+MNPDG ++ R N DLNR A+ + Sbjct: 202 DTEMQRLLEKADLYLVPNMNPDG--------AFHGNLRTNAAGQDLNR----AWLEPSAE 249 Query: 167 RQPETVAVMKWLKTETFVLSANLHG 191 R PE V + +K L ++HG Sbjct: 250 RSPEVWFVQQEMKRHGVDLFLDIHG 274 >1KWM-A nrPDB Length = 402 Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 57/282 (20%), Positives = 107/282 (37%), Gaps = 42/282 (14%) Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81 Y++ E +EA+ + VA ++ IG + +GR +++L VG+ + P Sbjct: 104 YNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNK----PAIFMDCG 159 Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141 H E + + V + G++ ++T L+N +++P +N DG+ ++ Sbjct: 160 FHAREWISPAFCQWFVREAVRTYGREIQVTELLNKLDFYVLPVLNIDGYIYTWTKSRFWR 219 Query: 142 IGRENYN-----QYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTET 182 R + D NRNF + SR P ET A+ +++ + Sbjct: 220 KTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKL 279 Query: 183 FVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD 240 + A +H + + YP+ Y+ L ++ LA ++ Sbjct: 280 SSIKAYLTIHSYSQMMIYPYS---------YAYKLGENNAELNALAKATVKELASLH--- 327 Query: 241 ECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282 K + G T + YP GG D+ Y + T EL Sbjct: 328 --GTKYTYGPGAT---TIYPAAGGSDDWAYDQGIRYSFTFEL 364 >1ZLI-A nrPDB Length = 309 Score = 48.5 bits (114), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 57/282 (20%), Positives = 106/282 (37%), Gaps = 42/282 (14%) Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81 Y+ E +EA+ + VA ++ IG + +GR +++L VG+ + P Sbjct: 11 YNNWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNK----PAIFMDCG 66 Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141 H E + + V + G++ ++T L+N +++P +N DG+ ++ Sbjct: 67 FHAREWISPAFCQWFVREAVRTYGREIQVTELLNKLDFYVLPVLNIDGYIYTWTKSRFWR 126 Query: 142 IGRENYN-----QYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTET 182 R + D NRNF + SR P ET A+ +++ + Sbjct: 127 KTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKL 186 Query: 183 FVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD 240 + A +H + + YP+ Y+ L ++ LA ++ Sbjct: 187 SSIKAYLTIHSYSQMMIYPYS---------YAYKLGENNAELNALAKATVKELASLH--- 234 Query: 241 ECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282 K + G T + YP GG D+ Y + T EL Sbjct: 235 --GTKYTYGPGAT---TIYPAAGGSDDWAYDQGIRYSFTFEL 271 >4BD9-A nrPDB Length = 310 Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 36/159 (22%), Positives = 67/159 (42%), Gaps = 11/159 (6%) Query: 19 DFNYHRQEGMEAF---LKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75 +FNY +EA + +A ++ + IG S + R ++VL +F + P Sbjct: 6 NFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVL---KFSTGKGVRRPA 62 Query: 76 FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135 A +H E + + + +V+ +DP IT+++ I ++P NPDG+ + Sbjct: 63 VWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQT 122 Query: 136 PDCYYSIGR-----ENYNQYDLNRNFPDAFEYNNVSRQP 169 + + R + D NRN+ +F S P Sbjct: 123 QNRLWRKTRSRNPGSSCIGADPNRNWNASFAGKGASDNP 161 >2BOA-A nrPDB Length = 404 Score = 45.4 bits (106), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 28/115 (24%), Positives = 53/115 (46%), Gaps = 6/115 (5%) Query: 19 DFNYHRQEGMEAF---LKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75 +FNY +EA + +A ++ + IG S + R ++VL +F + P Sbjct: 100 NFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVL---KFSTGKGVRRPA 156 Query: 76 FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGF 130 A +H E + + + +V+ +DP IT+++ I ++P NPDG+ Sbjct: 157 VWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGY 211 >3OSL-A nrPDB Length = 401 Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 62/284 (21%), Positives = 110/284 (38%), Gaps = 41/284 (14%) Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80 YH + ++++ + + Y + IG S + L+VL V + KE R + Sbjct: 100 QYHSLNEIYSWIEVMTERYPDMVEKIHIGSSYEKYPLYVLKVSK--KEQRAKNAMW-IDC 156 Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140 +H E + L + + GK+ TNL+ +IMP +N DG++ K D + Sbjct: 157 GIHAREWISPAFCLWFVGSVTYYYGKEKMHTNLLKHMDFYIMPVVNVDGYDYTWKKDRMW 216 Query: 141 SIGRENYNQ-----YDLNRNFP------DAFEYNNVSR---------QPETVAVMKWLKT 180 R + + DLNRNF + ++ S +PE AV +L+ Sbjct: 217 RKNRSLHEKNACVGTDLNRNFASKHWCGEGASSSSCSEIYCGTYPESEPEVKAVADFLRR 276 Query: 181 ETFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKK 238 + A ++H + +P+ YSRS + D + +A N+ + Sbjct: 277 NIKHIKAYISMHSYSQKIVFPYS---------YSRSRSKDHEELSLVAREAVFAMENIHR 327 Query: 239 GDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282 + + +G + S Y GG D+ Y + T EL Sbjct: 328 N------IRYTHG-SGSESLYLAPGGSDDWIYDLGIKYSFTFEL 364 >4B6Z-A nrPDB Length = 405 Score = 44.7 bits (104), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 50/179 (27%), Positives = 77/179 (43%), Gaps = 27/179 (15%) Query: 20 FNYHRQEGMEAFLKTVAQ-NYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKY 78 F + +E AFL V Q +SV L G++V+GR + +L +G + G P+ K Sbjct: 132 FEPYSEERHAAFLGAVQQLPQASVVEL---GRTVEGRPMSLLTLGTPETD---GAPKKKV 185 Query: 79 --VANMHGDETVGRELLLHLIDYLVTSD--GKDPEITNLINSTRIHIMPSMNPDGFEAVK 134 +A H E++ + L+ L DP L + HI+P+MNPDG Sbjct: 186 WIIARQHPGESMAEWFVEGLVKRLAGWGDWAGDPVARKLYDRVTFHIVPNMNPDG----- 240 Query: 135 KPDCYYSIGRENYNQYDLNRNF--PDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHG 191 + R N +LNR + PDA R PE +AV + + ++HG Sbjct: 241 ---SVHGNLRTNAAGANLNREWMAPDA------ERSPEVLAVRDAIHAIGCDMFFDIHG 290 >3D4U-A nrPDB Length = 309 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 62/284 (21%), Positives = 110/284 (38%), Gaps = 41/284 (14%) Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80 YH + ++++ + + Y + IG S + L+VL V + KE R + Sbjct: 8 QYHSLNEIYSWIEVMTERYPDMVEKIHIGSSYEKYPLYVLKVSK--KEQRAKNAMW-IDC 64 Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140 +H E + L + + GK+ TNL+ +IMP +N DG++ K D + Sbjct: 65 GIHAREWISPAFCLWFVGSVTYYYGKEKMHTNLLKHMDFYIMPVVNVDGYDYTWKKDRMW 124 Query: 141 SIGRENYNQ-----YDLNRNFP------DAFEYNNVSR---------QPETVAVMKWLKT 180 R + + DLNRNF + ++ S +PE AV +L+ Sbjct: 125 RKNRSLHEKNACVGTDLNRNFASKHWCGEGASSSSCSEIYCGTYPESEPEVKAVADFLRR 184 Query: 181 ETFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKK 238 + A ++H + +P+ YSRS + D + +A N+ + Sbjct: 185 NIKHIKAYISMHSYSQKIVFPYS---------YSRSRSKDHEELSLVAREAVFAMENIHR 235 Query: 239 GDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282 + + +G + S Y GG D+ Y + T EL Sbjct: 236 N------IRYTHG-SGSESLYLAPGGSDDWIYDLGIKYSFTFEL 272 >1DTD-A nrPDB Length = 303 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 36/154 (23%), Positives = 63/154 (40%), Gaps = 11/154 (7%) Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81 YH E + + + + + +IG S + R + VL + P A Sbjct: 6 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-----PAIWLDAG 60 Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141 +H E V + L + +V+ GKDP IT+++++ I ++P NPDG+ + + + Sbjct: 61 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR 120 Query: 142 IGRENYNQ------YDLNRNFPDAFEYNNVSRQP 169 R + D NRN+ F S P Sbjct: 121 KTRSKVSAGSLCVGVDPNRNWDAGFGGPGASSNP 154 >1JQG-A nrPDB Length = 433 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 53/218 (24%), Positives = 85/218 (38%), Gaps = 43/218 (19%) Query: 23 HRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN- 81 H E ++A+L+ +A+ + +V + GKS +GR++ K RI F+ + Sbjct: 122 HSYEEVDAYLQELAKEFPNVVTVVEGGKSFEGRSI---------KYLRISTTNFQDASKP 172 Query: 82 -------MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVK 134 +H E V L+ I LV D ++LIN+ I+P NPDG+ Sbjct: 173 VVMMQSLLHCREWVTLPATLYAIHKLVI----DVTESDLINNIDWIILPVANPDGYVHTF 228 Query: 135 KPDCYYSIGRENYNQ-------YDLNRNF-------------PDAFEYNNVSRQPETVAV 174 D Y+ R DLNRNF D F + +PE+ + Sbjct: 229 GGDRYWRKNRATGYMAGNLCMGVDLNRNFGMNWGTASSSSVCSDTFHGRSAFSEPESSVI 288 Query: 175 MKWLKTE--TFVLSANLHGGALVASYPFDNGVQATGAL 210 + L ++H + Y + NGV + AL Sbjct: 289 RDIIAEHRNRMALYLDIHSFGSMILYGYGNGVLPSNAL 326 >3K2K-A nrPDB Length = 403 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 48/177 (27%), Positives = 75/177 (42%), Gaps = 23/177 (12%) Query: 20 FNYHRQEGMEAFLKTVAQN-YSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKY 78 F + +E FL V Q +SV L G++V+GR + ++V+G P E + Sbjct: 130 FEPYSEERHSEFLGAVQQMPQASVVEL---GRTVEGRPMSLVVLGT-PDEAGAAKKKVWI 185 Query: 79 VANMHGDETVGRELLLHLIDYLVTSD--GKDPEITNLINSTRIHIMPSMNPDGFEAVKKP 136 +A H E++ + L+ LV DP L + +I+P+MNPDG Sbjct: 186 IARQHPGESMAEWFIEGLVKRLVGWGDWSGDPVARKLYDHATFYIVPNMNPDG------- 238 Query: 137 DCYYSIGRENYNQYDLNRNF--PDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHG 191 + R N +LNR + PDA R PE + V + L ++HG Sbjct: 239 -SVHGNLRTNAAGANLNREWMEPDA------ERSPEVLVVRDAIHAIGCDLFFDIHG 288 >1AYE-A nrPDB Length = 401 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 36/153 (23%), Positives = 63/153 (41%), Gaps = 10/153 (6%) Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81 YH E + + + + + +IG S + R + VL + P A Sbjct: 105 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-----PAIWLDAG 159 Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141 +H E V + L + +V+ GKDP IT+++++ I ++P NPDG+ + + + Sbjct: 160 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR 219 Query: 142 IGRENYN-----QYDLNRNFPDAFEYNNVSRQP 169 R + D NRN+ F S P Sbjct: 220 KTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNP 252 >5AQ0-A nrPDB Length = 82 Score = 40.8 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 4/69 (5%) Query: 314 GVKGQVFDQ-NGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDP- 371 GVKG V D G+ L N + V H T ++G++Y LL+PG+Y + V + G+ P Sbjct: 2 GVKGFVKDSITGSGLENATISVAGINH--NITTGRFGDFYRLLVPGTYNLTVVLTGYMPL 59 Query: 372 HITKVIIPE 380 +T V++ E Sbjct: 60 TVTNVVVKE 68 >4UIB-A nrPDB Length = 307 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 25/109 (22%), Positives = 49/109 (44%), Gaps = 4/109 (3%) Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81 Y+ E +EA+ K V + +IG + G N+++L VG+ P ++ P Sbjct: 9 YNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGK-PGPNK---PAIFMDCG 64 Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGF 130 +H E + + V + G + +T +N +++P +N DG+ Sbjct: 65 IHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGY 113 >3GLJ-A nrPDB Length = 401 Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust. Identities = 25/109 (22%), Positives = 48/109 (44%), Gaps = 4/109 (3%) Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81 Y+ E +EA+ K V + +IG + G N+++L VG+ P ++ P Sbjct: 104 YNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGK-PGPNK---PAIFMDCG 159 Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGF 130 H E + + V + G + +T +N +++P +N DG+ Sbjct: 160 FHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGY 208 >1NSA-A nrPDB Length = 395 Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust. Identities = 23/109 (21%), Positives = 50/109 (45%), Gaps = 4/109 (3%) Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81 Y+ E +EA+ + V + +IG + G N+++L VG+ P ++ P Sbjct: 98 YNNWETIEAWTEQVTSKNPDLISRSAIGTTFDGDNIYLLKVGK-PGSNK---PAIFMDCG 153 Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGF 130 H E + + + V + G + +T +++ +++P +N DG+ Sbjct: 154 FHAREWISQAFCQWFVRDAVRTYGYEAHMTEFLDNLDFYVLPVLNIDGY 202 >3KGQ-A nrPDB Length = 309 Score = 36.2 bits (82), Expect = 0.027, Method: Compositional matrix adjust. Identities = 32/154 (20%), Positives = 55/154 (35%), Gaps = 9/154 (5%) Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80 YH + + F+ + + + IG+S +GR ++VL P Sbjct: 11 TYHTLDEIYDFMDLLVAEHPQLVSKLQIGRSYEGRPIYVLKFSTGGSNR----PAIWIDL 66 Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140 +H E + + + G+DP T +++S I + NPDGF + + Sbjct: 67 GIHSREWITQATGVWFAKKFTEDYGQDPSFTAILDSMDIFLEIVTNPDGFAFTHSQNRLW 126 Query: 141 SIGRENYNQ-----YDLNRNFPDAFEYNNVSRQP 169 R + D NRN+ F S P Sbjct: 127 RKTRSVTSSSLCVGVDANRNWDAGFGKAGASSSP 160 >3L2N-A nrPDB Length = 395 Score = 36.2 bits (82), Expect = 0.032, Method: Compositional matrix adjust. Identities = 25/83 (30%), Positives = 44/83 (53%), Gaps = 8/83 (9%) Query: 48 IGKSVKGRNLWVLVVGRF-PKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGK 106 +G ++ GR++ ++ VG P + I I A H ET+ L+ L++ L+ +D Sbjct: 154 LGLTLDGRDMTLVKVGDDDPSKKSIWI-----TARQHPGETMAEWLVEGLLNQLLDNDC- 207 Query: 107 DPEITNLINSTRIHIMPSMNPDG 129 P L++ +I+P+MNPDG Sbjct: 208 -PTSKALLDKANFYIVPNMNPDG 229 >3D68-A nrPDB Length = 424 Score = 35.0 bits (79), Expect = 0.068, Method: Compositional matrix adjust. Identities = 34/143 (23%), Positives = 61/143 (42%), Gaps = 10/143 (6%) Query: 21 NYHRQEGMEAFLKTVAQNY-SSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79 YH + ++++ + + + +T +H IG S + L+VL V + + I Sbjct: 123 QYHSLNEIYSWIEFITERHPDMLTKIH-IGSSFEKYPLYVLKVSGKEQTAKNAI---WID 178 Query: 80 ANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCY 139 +H E + L I ++ G + TNL+ ++MP +N DG++ K + Sbjct: 179 CGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRM 238 Query: 140 YSIGRENYNQ-----YDLNRNFP 157 + R Y DLNRNF Sbjct: 239 WRKNRSFYANNHCIGTDLNRNFA 261 >3LMS-A nrPDB Length = 309 Score = 35.0 bits (79), Expect = 0.072, Method: Compositional matrix adjust. Identities = 34/144 (23%), Positives = 61/144 (42%), Gaps = 10/144 (6%) Query: 21 NYHRQEGMEAFLKTVAQNY-SSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79 YH + ++++ + + + +T +H IG S + L+VL V + + I Sbjct: 8 QYHSLNEIYSWIEFITERHPDMLTKIH-IGSSFEKYPLYVLKVSGKEQAAKNAIW---ID 63 Query: 80 ANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCY 139 +H E + L I ++ G + TNL+ ++MP +N DG++ K + Sbjct: 64 CGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRM 123 Query: 140 YSIGRENYNQ-----YDLNRNFPD 158 + R Y DLNRNF Sbjct: 124 WRKNRSFYANNHCIGTDLNRNFAS 147 >4UEE-A nrPDB Length = 309 Score = 33.5 bits (75), Expect = 0.18, Method: Compositional matrix adjust. Identities = 36/155 (23%), Positives = 60/155 (38%), Gaps = 11/155 (7%) Query: 21 NYHRQEGMEAFLKT-VAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79 YH E + FL VA+N V+ + IG + +GR ++VL + P Sbjct: 11 TYHTLEEIYDFLDLLVAENPHLVSKIQ-IGNTYEGRPIYVLKFSTGGSKR----PAIWID 65 Query: 80 ANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCY 139 +H E V + + + G+D T ++++ I + NPDGF + Sbjct: 66 TGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRM 125 Query: 140 YSIGRENYN-----QYDLNRNFPDAFEYNNVSRQP 169 + R + D NRN+ F + S P Sbjct: 126 WRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNP 160 >2QVP-A nrPDB Length = 275 Score = 33.5 bits (75), Expect = 0.21, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 30/62 (48%), Gaps = 9/62 (14%) Query: 69 HRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPD 128 + G+P A HG+E+ G LLH + L D E+ +N + ++P +NP Sbjct: 61 QKAGLPNLLISAGFHGEESAGPWGLLHFLSQL------DGELFKRVN---LSVLPLVNPT 111 Query: 129 GF 130 GF Sbjct: 112 GF 113 >5MRV-A nrPDB Length = 355 Score = 33.5 bits (75), Expect = 0.21, Method: Compositional matrix adjust. Identities = 33/179 (18%), Positives = 72/179 (40%), Gaps = 22/179 (12%) Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81 YH + +++ +++ Y V H +G + + ++ L + + P + I Sbjct: 56 YHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPIYYLKISQ-PSGNPKKIIWMD--CG 112 Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141 +H E + + ++ + + I L+ + +++P +N DG+ D + Sbjct: 113 IHAREWIAPAFCQWFVKEILQNHKDNSRIRKLLRNLDFYVLPVLNIDGYIYTWTTDRLWR 172 Query: 142 IGRENYNQ-----YDLNRNFPDAFEYNNVSR--------------QPETVAVMKWLKTE 181 R +N DLNRNF ++ SR +PET AV +++++ Sbjct: 173 KSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVASFIESK 231 >5OM9-A nrPDB Length = 419 Score = 32.7 bits (73), Expect = 0.29, Method: Compositional matrix adjust. Identities = 36/155 (23%), Positives = 60/155 (38%), Gaps = 11/155 (7%) Query: 21 NYHRQEGMEAFLKT-VAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79 YH E + FL VA+N V+ + IG + +GR ++VL + P Sbjct: 121 TYHTLEEIYDFLDLLVAENPHLVSKIQ-IGNTYEGRPIYVLKFSTGGSKR----PAIWID 175 Query: 80 ANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCY 139 +H E V + + + G+D T ++++ I + NPDGF + Sbjct: 176 TGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRM 235 Query: 140 YSIGRENYN-----QYDLNRNFPDAFEYNNVSRQP 169 + R + D NRN+ F + S P Sbjct: 236 WRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNP 270 >1PCA-A nrPDB Length = 403 Score = 32.0 bits (71), Expect = 0.53, Method: Compositional matrix adjust. Identities = 30/154 (19%), Positives = 58/154 (37%), Gaps = 9/154 (5%) Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80 YH E + F+ + + ++ IG+S +GR ++VL P + Sbjct: 106 TYHTLEEIYDFMDILVAEHPALVSKLQIGRSYEGRPIYVLKFSTGGSNR----PAIWIDS 161 Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140 +H E + + + + + G++ T +++S I + NP+GF + + Sbjct: 162 GIHSREWITQASGVWFAKKITENYGQNSSFTAILDSMDIFLEIVTNPNGFAFTHSDNRLW 221 Query: 141 SIGRENYN-----QYDLNRNFPDAFEYNNVSRQP 169 R + D NRN+ F S P Sbjct: 222 RKTRSKASGSLCVGSDSNRNWDAGFGGAGASSSP 255 >5HXD-A nrPDB Length = 237 Score = 32.0 bits (71), Expect = 0.60, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 17/63 (26%) Query: 118 RIHIMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDA--------FEYNNVSRQP 169 R H++ +NPDG C + R N N DLNRNFP A + +N+ + + Sbjct: 72 RHHVVLCVNPDG--------CQLGL-RANANGVDLNRNFPAANWKEGETVYRWNSAAEER 122 Query: 170 ETV 172 + V Sbjct: 123 DVV 125 >4GFJ-A nrPDB Length = 685 Score = 31.2 bits (69), Expect = 0.86, Method: Compositional matrix adjust. Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 4/73 (5%) Query: 29 EAF-LKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEH-RIGIPEFKYVANMHGDE 86 EAF L+T A+ Y L IG+ + +L L +G PK I PEFK++ N+ G Sbjct: 574 EAFDLETAAELYERYGSLKEIGRRLSYDDL--LELGATPKAAAEIKGPEFKFLLNIEGVG 631 Query: 87 TVGRELLLHLIDY 99 E +L +DY Sbjct: 632 PKLAERILEAVDY 644 >5HM5-A nrPDB Length = 854 Score = 31.2 bits (69), Expect = 0.97, Method: Compositional matrix adjust. Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 4/73 (5%) Query: 29 EAF-LKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEH-RIGIPEFKYVANMHGDE 86 EAF L+T A+ Y L IG+ + +L L +G PK I PEFK++ N+ G Sbjct: 574 EAFDLETAAELYERYGSLKEIGRRLSYDDL--LELGATPKAAAEIKGPEFKFLLNIEGVG 631 Query: 87 TVGRELLLHLIDY 99 E +L +DY Sbjct: 632 PKLAERILEAVDY 644 >3IEH-A nrPDB Length = 276 Score = 31.2 bits (69), Expect = 1.0, Method: Compositional matrix adjust. Identities = 29/127 (22%), Positives = 43/127 (33%), Gaps = 20/127 (15%) Query: 70 RIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDG 129 + G+P A HG+E+ G LLH + +L + ++P +NP G Sbjct: 63 KSGLPSLLISAGFHGEESAGPWGLLHFL---------SEASADLFERVNLSLLPLVNPTG 113 Query: 130 FEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANL 189 F + +N+Y N N FE T K L +L A Sbjct: 114 FSRGHR-----------FNKYGENPNRGFVFENGKPKANEHTSVEGKLLLDHAQLLIAAC 162 Query: 190 HGGALVA 196 G L Sbjct: 163 RDGILTC 169 >2C1C-A nrPDB Length = 312 Score = 30.0 bits (66), Expect = 2.2, Method: Compositional matrix adjust. Identities = 38/183 (20%), Positives = 71/183 (38%), Gaps = 20/183 (10%) Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVG--RFPKEHRIGIPEFKY 78 NY E ++ +L + + Y V + + +S +GR + + + F E++ P Sbjct: 5 NYQELEVIDEYLDYIGEKYPDVATVVNAAESFEGRPIKYIKISTTNFEDENK---PVIFI 61 Query: 79 VANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDC 138 +H E + + I LV +D +L+ ++P +NPDG++ + Sbjct: 62 DGGIHAREWISPPSVTWAIHKLV----EDVTENDLLEKFDWILLPVVNPDGYKYTFTNER 117 Query: 139 YYSIGRENYNQ--------YDLNRNFPDAFEYNNVSRQPET---VAVMKWLKTETFVLSA 187 ++ R N D NRNF + S P + + + ET V+ Sbjct: 118 FWRKTRSTNNNPLSQICRGADGNRNFDFVWNSIGTSNSPCSDIYAGTSAFSEVETRVVRD 177 Query: 188 NLH 190 LH Sbjct: 178 ILH 180 >6D97-A nrPDB Length = 547 Score = 29.6 bits (65), Expect = 2.6, Method: Compositional matrix adjust. Identities = 36/151 (23%), Positives = 64/151 (42%), Gaps = 16/151 (10%) Query: 255 GYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLG 314 G+ W L +Q+ +Y+ C + S K + L N + + L+E +K+ L Sbjct: 296 GFDWKILGPDVQEVDYVAWVCDQDAYACSGQKCSAQSVLFMHKNWSSSGLLEKMKK--LS 353 Query: 315 VKGQVFDQNGNPLPNVIVE--VQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVP----G 368 + ++ D P+ V E ++ ++ R +K +L G + N ++P Sbjct: 354 ERRKLEDLTIGPVLTVTTEAMIEHMNNLLKIRGSK------VLFGGEPLANHSIPKIYGA 407 Query: 369 HDPHITKVIIPE--KSQNFSALKKDILLPFQ 397 P V + E KS NF + K+I PFQ Sbjct: 408 MKPTAVFVPLEEILKSGNFELVTKEIFGPFQ 438 >3B2Y-A nrPDB Length = 275 Score = 29.3 bits (64), Expect = 3.2, Method: Compositional matrix adjust. Identities = 17/64 (26%), Positives = 29/64 (45%), Gaps = 9/64 (14%) Query: 69 HRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPD 128 R +P + HG+E G +LH + G P + +N + ++P +NP Sbjct: 62 QRSDLPSLLISSGFHGEEAAGPWGMLHFLR------GLQPALFERVN---LSLLPLVNPT 112 Query: 129 GFEA 132 GF+A Sbjct: 113 GFKA 116 >3N5M-A nrPDB Length = 452 Score = 28.5 bits (62), Expect = 6.5, Method: Compositional matrix adjust. Identities = 34/135 (25%), Positives = 50/135 (37%), Gaps = 24/135 (17%) Query: 128 DGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTET---FV 184 GF V PDCY G E N YD V E VM W +ET F+ Sbjct: 174 SGFLHVTPPDCYRMPGIERENIYD-------------VECVKEVDRVMTWELSETIAAFI 220 Query: 185 LSANLHGGA-LVASYPFDNGVQATGALYSRSLTPDDDV--FQYLAHTYASRNPNMKKGDE 241 + + GG L+A + V T + L D+ + F + N ++K Sbjct: 221 MEPIITGGGILMAPQDYMKAVHETCQKHGALLISDEVICGFGRTGKAFGFMNYDVK---- 276 Query: 242 CKNKMNFPNGVTNGY 256 + + G+T+ Y Sbjct: 277 -PDIITMAKGITSAY 290 >1SEZ-A nrPDB Length = 504 Score = 28.1 bits (61), Expect = 8.8, Method: Compositional matrix adjust. Identities = 17/57 (29%), Positives = 27/57 (47%), Gaps = 3/57 (5%) Query: 192 GALVASYPFDNGVQATGALYSRSLTPD---DDVFQYLAHTYASRNPNMKKGDECKNK 245 G LV S +G++ G L+S + PD ++V+ Y SRN + K + K Sbjct: 354 GVLVPSKEQQHGLKTLGTLFSSMMFPDRAPNNVYLYTTFVGGSRNRELAKASRTELK 410 >1YKN-B nrPDB Length = 238 Score = 27.7 bits (60), Expect = 9.4, Method: Compositional matrix adjust. Identities = 11/20 (55%), Positives = 15/20 (75%) Query: 315 VKGQVFDQNGNPLPNVIVEV 334 V G+V DQ G P+PN +VE+ Sbjct: 80 VAGRVVDQYGKPVPNTLVEM 99 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1UWY-A nrPDB 652 0.0 3MN8-A nrPDB 484 e-137 1QMU-A nrPDB 483 e-137 2NSM-A nrPDB 444 e-125 1KWM-A nrPDB 283 1e-76 1ZLI-A nrPDB 282 2e-76 3OSL-A nrPDB 267 1e-71 3D4U-A nrPDB 265 3e-71 4UIB-A nrPDB 260 6e-70 2BOA-A nrPDB 250 1e-66 4BD9-A nrPDB 248 3e-66 3V7Z-A nrPDB 242 2e-64 1AYE-A nrPDB 238 3e-63 1DTD-A nrPDB 237 9e-63 1JQG-A nrPDB 203 2e-52 3K2K-A nrPDB 175 3e-44 4B6Z-A nrPDB 166 2e-41 4A39-A nrPDB 152 2e-37 5AQ0-A nrPDB 90 2e-18 Sequences not found previously or not previously below threshold: 3GLJ-A nrPDB 267 7e-72 1NSA-A nrPDB 261 4e-70 3D68-A nrPDB 235 5e-62 3LMS-A nrPDB 233 1e-61 3KGQ-A nrPDB 223 2e-58 5OM9-A nrPDB 215 5e-56 4UEE-A nrPDB 212 3e-55 1PCA-A nrPDB 211 4e-55 5MRV-A nrPDB 197 7e-51 1CPB-B nrPDB 171 7e-43 2C1C-A nrPDB 165 3e-41 3L2N-A nrPDB 121 6e-28 1CPB-A nrPDB 93 3e-19 2QVP-A nrPDB 51 1e-06 3B2Y-A nrPDB 49 5e-06 5HXD-A nrPDB 47 2e-05 3IEH-A nrPDB 45 6e-05 4OKO-A nrPDB 41 0.001 2QJ8-A nrPDB 37 0.014 4RWR-A nrPDB 36 0.025 4AXV-A nrPDB 36 0.035 2OKL-A nrPDB 34 0.20 5OCR-A nrPDB 32 0.53 5JBE-A nrPDB 31 0.79 5VOC-B nrPDB 31 1.3 3A22-A nrPDB 30 1.5 2AZQ-A nrPDB 30 2.7 3ZHL-A nrPDB 29 3.2 4E79-A nrPDB 29 5.3 4M1U-A nrPDB 29 5.5 2HN1-A nrPDB 29 6.2 1JQP-A nrPDB 28 9.4 >1UWY-A nrPDB Length = 426 Score = 652 bits (1683), Expect = 0.0, Method: Composition-based stats. Identities = 426/426 (100%), Positives = 426/426 (100%) Query: 18 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK Sbjct: 1 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 60 Query: 78 YVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPD 137 YVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPD Sbjct: 61 YVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPD 120 Query: 138 CYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVAS 197 CYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVAS Sbjct: 121 CYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVAS 180 Query: 198 YPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYS 257 YPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYS Sbjct: 181 YPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYS 240 Query: 258 WYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKG 317 WYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKG Sbjct: 241 WYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKG 300 Query: 318 QVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVI 377 QVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVI Sbjct: 301 QVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVI 360 Query: 378 IPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLPDHSAATKPSLFLFLVSL 437 IPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLPDHSAATKPSLFLFLVSL Sbjct: 361 IPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLPDHSAATKPSLFLFLVSL 420 Query: 438 LHIFFK 443 LHIFFK Sbjct: 421 LHIFFK 426 >3MN8-A nrPDB Length = 435 Score = 484 bits (1245), Expect = e-137, Method: Composition-based stats. Identities = 169/396 (42%), Positives = 246/396 (62%), Gaps = 21/396 (5%) Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80 +Y QE +E + + Y + +H +G+S++GRNL L + R + + P KY+A Sbjct: 39 HYASQEQLEDLFAGLEKAYPNQAKVHFLGRSLEGRNLLALQISRNTRSRNLLTPPVKYIA 98 Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140 NMHGDETVGR+LL+++ YL+ + + ++ L+NST I+++P+MNPDG+ ++ +C Sbjct: 99 NMHGDETVGRQLLVYMAQYLLGNHERISDLGQLVNSTDIYLVPTMNPDGYALSQEGNCES 158 Query: 141 ---SIGRENYNQYDLNRNFPDAFEYNNV------SRQPETVAVMKWLKTETFVLSANLHG 191 +GR N DLNR+FPD E ++V SRQPET A++ W+ ++ FVLSAN HG Sbjct: 159 LPNYVGRGNAANIDLNRDFPDRLEQSHVHQLRAQSRQPETAALVNWIVSKPFVLSANFHG 218 Query: 192 GALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNG 251 GA+VASYP+DN + A SLTPDD VF+ LAHTY+ +P M+KG+ C + +F G Sbjct: 219 GAVVASYPYDNSL-AHNECCEESLTPDDRVFKQLAHTYSDNHPIMRKGNNCND--SFSGG 275 Query: 252 VTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQV 311 +TNG WY L GGMQD+NY ++ CFE+T+ELSCCKYP LP W NKASL++ ++Q Sbjct: 276 ITNGAHWYELSGGMQDFNYAFSNCFELTIELSCCKYPAASTLPQEWQRNKASLLQLLRQA 335 Query: 312 HLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHD- 370 H+G+KG V D +G P+ + V V + P RT+K GEY+ LL PG Y ++ + G+ Sbjct: 336 HIGIKGLVTDASGFPIADANVYVAGLEEK-PMRTSKRGEYWRLLTPGLYSVHASAFGYQT 394 Query: 371 --PHITKVIIPEKSQNFSALKKDI-LLPFQGQLDSI 403 P +V + N AL+ D L P + D I Sbjct: 395 SAPQQVRVT----NDNQEALRLDFKLAPVETNFDGI 426 >1QMU-A nrPDB Length = 380 Score = 483 bits (1244), Expect = e-137, Method: Composition-based stats. Identities = 187/371 (50%), Positives = 246/371 (66%), Gaps = 9/371 (2%) Query: 15 VAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIP 74 V +DF +H ME FL+ A Y S+T L+S+GKSV+ R L+V+ + P H G P Sbjct: 3 VQPVDFRHHHFSDMEIFLRRYANEYPSITRLYSVGKSVELRELYVMEISDNPGIHEAGEP 62 Query: 75 EFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVK 134 EFKY+ NMHG+E VGRELLL+LI+YL + G DPE+T+L+ STRIHIMPSMNPDG+E + Sbjct: 63 EFKYIGNMHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVQSTRIHIMPSMNPDGYEKSQ 122 Query: 135 KPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGAL 194 + D ++GR N N YDLNRNFPD F QPET+AVM WLKT FVLSANLHGG+L Sbjct: 123 EGDRGGTVGRNNSNNYDLNRNFPDQFFQVTDPPQPETLAVMSWLKTYPFVLSANLHGGSL 182 Query: 195 VASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKN---KMNFPNG 251 V +YPFD+ Q A+YS+S PDD VFQ LA +Y+ N M +G CK+ FP+G Sbjct: 183 VVNYPFDDDEQGI-AIYSKS--PDDAVFQQLALSYSKENKKMYQGSPCKDLYPTEYFPHG 239 Query: 252 VTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQV 311 +TNG WY + GGMQD+NY+ CFE+T+EL C KYP+ E+LP +W N+ SL+++IKQV Sbjct: 240 ITNGAQWYNVPGGMQDWNYLNTNCFEVTIELGCVKYPKAEELPKYWEQNRRSLLQFIKQV 299 Query: 312 HLGVKGQVFDQ-NGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHD 370 H G+ G V D +G + N + V D H P T K G+Y+ LL+ G+Y + + G+D Sbjct: 300 HRGIWGFVLDATDGRGILNATISVADINH--PVTTYKDGDYWRLLVQGTYKVTASARGYD 357 Query: 371 PHITKVIIPEK 381 P V + K Sbjct: 358 PVTKTVEVDSK 368 >2NSM-A nrPDB Length = 439 Score = 444 bits (1141), Expect = e-125, Method: Composition-based stats. Identities = 169/387 (43%), Positives = 229/387 (59%), Gaps = 30/387 (7%) Query: 18 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77 L F +HR + + L V +T ++SIG+SV+GR+L+VL P H PE K Sbjct: 2 LAFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVK 61 Query: 78 YVANMHGDETVGRELLLHLIDYLVTSD-GKDPEITNLINSTRIHIMPSMNPDGFE--AVK 134 YV NMHG+E +GREL+L L ++L ++ I LI TRIHI+PSMNPDG+E A + Sbjct: 62 YVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQ 121 Query: 135 KPDC-YYSIGRENYNQYDLNRNFPDAFEY-----------------NNVSRQ--PETVAV 174 P+ Y +GR N N DLNRNFPD Y +N Q PET AV Sbjct: 122 GPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLPDNWKSQVEPETRAV 181 Query: 175 MKWLKTETFVLSANLHGGALVASYPFDNGVQ---ATGALYSRSLTPDDDVFQYLAHTYAS 231 ++W+ + FVLSANLHGGA+VA+YP+D + + + TPDD +FQ LA Y+ Sbjct: 182 IRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLAKVYSY 241 Query: 232 RNPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREE 291 + M +G C + FP+G+TNG SWY L GMQD+NY+ CFEITLELSC K+P EE Sbjct: 242 AHGWMFQGWNCGDY--FPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPPEE 299 Query: 292 KLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEY 351 +L W NK +LI++++QVH G+KG V DQN N L N ++ V H + +G+Y Sbjct: 300 ELQREWLGNKEALIQFLEQVHQGIKGMVLDQNYNNLANAVISVSGINHD--VTSGDHGDY 357 Query: 352 YLLLLPGSYIINVTVPGHDPHITKVII 378 + LLLPG Y ++ T PG+DP V + Sbjct: 358 FRLLLPGIYTVSATAPGYDPETVTVTV 384 >1KWM-A nrPDB Length = 402 Score = 283 bits (724), Expect = 1e-76, Method: Composition-based stats. Identities = 57/283 (20%), Positives = 107/283 (37%), Gaps = 42/283 (14%) Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80 Y++ E +EA+ + VA ++ IG + +GR +++L VG+ + P Sbjct: 103 KYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNK----PAIFMDC 158 Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140 H E + + V + G++ ++T L+N +++P +N DG+ ++ Sbjct: 159 GFHAREWISPAFCQWFVREAVRTYGREIQVTELLNKLDFYVLPVLNIDGYIYTWTKSRFW 218 Query: 141 SIGRENYN-----QYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTE 181 R + D NRNF + SR P ET A+ +++ + Sbjct: 219 RKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNK 278 Query: 182 TFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKG 239 + A +H + + YP+ Y+ L ++ LA ++ Sbjct: 279 LSSIKAYLTIHSYSQMMIYPYS---------YAYKLGENNAELNALAKATVKELASLH-- 327 Query: 240 DECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282 K + G T + YP GG D+ Y + T EL Sbjct: 328 ---GTKYTYGPGAT---TIYPAAGGSDDWAYDQGIRYSFTFEL 364 >1ZLI-A nrPDB Length = 309 Score = 282 bits (722), Expect = 2e-76, Method: Composition-based stats. Identities = 57/283 (20%), Positives = 106/283 (37%), Gaps = 42/283 (14%) Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80 Y+ E +EA+ + VA ++ IG + +GR +++L VG+ + P Sbjct: 10 KYNNWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNK----PAIFMDC 65 Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140 H E + + V + G++ ++T L+N +++P +N DG+ ++ Sbjct: 66 GFHAREWISPAFCQWFVREAVRTYGREIQVTELLNKLDFYVLPVLNIDGYIYTWTKSRFW 125 Query: 141 SIGRENYN-----QYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTE 181 R + D NRNF + SR P ET A+ +++ + Sbjct: 126 RKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNK 185 Query: 182 TFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKG 239 + A +H + + YP+ Y+ L ++ LA ++ Sbjct: 186 LSSIKAYLTIHSYSQMMIYPYS---------YAYKLGENNAELNALAKATVKELASLH-- 234 Query: 240 DECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282 K + G T + YP GG D+ Y + T EL Sbjct: 235 ---GTKYTYGPGAT---TIYPAAGGSDDWAYDQGIRYSFTFEL 271 >3GLJ-A nrPDB Length = 401 Score = 267 bits (682), Expect = 7e-72, Method: Composition-based stats. Identities = 55/283 (19%), Positives = 95/283 (33%), Gaps = 42/283 (14%) Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80 Y+ E +EA+ K V + +IG + G N+++L VG+ P Sbjct: 103 KYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKP----GPNKPAIFMDC 158 Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140 H E + + V + G + +T +N +++P +N DG+ + + Sbjct: 159 GFHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMW 218 Query: 141 SIGRE-----NYNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTE 181 R D NRNF + S P ET A+ +++ Sbjct: 219 RKTRSTNAGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNN 278 Query: 182 TFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKG 239 + A +H + + YP+ Y L ++ LA + Sbjct: 279 LSSIKAYLTIHSYSQMILYPYS---------YDYKLPENNAELNNLAKAAVKELATLY-- 327 Query: 240 DECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282 K + G T + YP GG D+ Y + T EL Sbjct: 328 ---GTKYTYGPGAT---TIYPAAGGSDDWAYDQGIKYSFTFEL 364 >3OSL-A nrPDB Length = 401 Score = 267 bits (681), Expect = 1e-71, Method: Composition-based stats. Identities = 61/289 (21%), Positives = 108/289 (37%), Gaps = 41/289 (14%) Query: 16 AALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75 ++ YH + ++++ + + Y + IG S + L+VL V + KE R Sbjct: 95 SSYYEQYHSLNEIYSWIEVMTERYPDMVEKIHIGSSYEKYPLYVLKVSK--KEQRAKN-A 151 Query: 76 FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135 +H E + L + + GK+ TNL+ +IMP +N DG++ K Sbjct: 152 MWIDCGIHAREWISPAFCLWFVGSVTYYYGKEKMHTNLLKHMDFYIMPVVNVDGYDYTWK 211 Query: 136 PDCYYSIGRENYN-----QYDLNRNF---------------PDAFEYNNVSRQPETVAVM 175 D + R + DLNRNF + + +PE AV Sbjct: 212 KDRMWRKNRSLHEKNACVGTDLNRNFASKHWCGEGASSSSCSEIYCGTYPESEPEVKAVA 271 Query: 176 KWLKTETFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRN 233 +L+ + A ++H + +P+ YSRS + D + +A Sbjct: 272 DFLRRNIKHIKAYISMHSYSQKIVFPYS---------YSRSRSKDHEELSLVAREAVFAM 322 Query: 234 PNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282 N+ + + + +G + S Y GG D+ Y + T EL Sbjct: 323 ENIHRN------IRYTHG-SGSESLYLAPGGSDDWIYDLGIKYSFTFEL 364 >3D4U-A nrPDB Length = 309 Score = 265 bits (676), Expect = 3e-71, Method: Composition-based stats. Identities = 61/289 (21%), Positives = 108/289 (37%), Gaps = 41/289 (14%) Query: 16 AALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75 ++ YH + ++++ + + Y + IG S + L+VL V + KE R Sbjct: 3 SSYYEQYHSLNEIYSWIEVMTERYPDMVEKIHIGSSYEKYPLYVLKVSK--KEQRAKN-A 59 Query: 76 FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135 +H E + L + + GK+ TNL+ +IMP +N DG++ K Sbjct: 60 MWIDCGIHAREWISPAFCLWFVGSVTYYYGKEKMHTNLLKHMDFYIMPVVNVDGYDYTWK 119 Query: 136 PDCYYSIGRENYN-----QYDLNRNF---------------PDAFEYNNVSRQPETVAVM 175 D + R + DLNRNF + + +PE AV Sbjct: 120 KDRMWRKNRSLHEKNACVGTDLNRNFASKHWCGEGASSSSCSEIYCGTYPESEPEVKAVA 179 Query: 176 KWLKTETFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRN 233 +L+ + A ++H + +P+ YSRS + D + +A Sbjct: 180 DFLRRNIKHIKAYISMHSYSQKIVFPYS---------YSRSRSKDHEELSLVAREAVFAM 230 Query: 234 PNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282 N+ + + + +G + S Y GG D+ Y + T EL Sbjct: 231 ENIHRN------IRYTHG-SGSESLYLAPGGSDDWIYDLGIKYSFTFEL 272 >1NSA-A nrPDB Length = 395 Score = 261 bits (667), Expect = 4e-70, Method: Composition-based stats. Identities = 53/283 (18%), Positives = 98/283 (34%), Gaps = 42/283 (14%) Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80 Y+ E +EA+ + V + +IG + G N+++L VG+ P Sbjct: 97 KYNNWETIEAWTEQVTSKNPDLISRSAIGTTFDGDNIYLLKVGKPGSNK----PAIFMDC 152 Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140 H E + + + V + G + +T +++ +++P +N DG+ + + Sbjct: 153 GFHAREWISQAFCQWFVRDAVRTYGYEAHMTEFLDNLDFYVLPVLNIDGYIYTWTKNRMW 212 Query: 141 SIGREN-----YNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTE 181 R D NRNF + S P ET A+ +++ Sbjct: 213 RKTRSTNAGSSCTGTDPNRNFNAGWCTVGASVNPCNETYCGSAAESEKETKALADFIRNN 272 Query: 182 TFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKG 239 + A +H + + YP+ Y L +D LA ++ Sbjct: 273 LSSIKAYLTIHSYSQMILYPYS---------YDYKLPENDAELNSLAKGAVKELASLY-- 321 Query: 240 DECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282 ++ G T + YP GG D+ Y + T EL Sbjct: 322 ---GTSYSYGPGST---TIYPAAGGSDDWAYNQGIKYSFTFEL 358 >4UIB-A nrPDB Length = 307 Score = 260 bits (665), Expect = 6e-70, Method: Composition-based stats. Identities = 54/283 (19%), Positives = 95/283 (33%), Gaps = 42/283 (14%) Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80 Y+ E +EA+ K V + +IG + G N+++L VG+ P Sbjct: 8 KYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKP----GPNKPAIFMDC 63 Query: 81 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 140 +H E + + V + G + +T +N +++P +N DG+ + + Sbjct: 64 GIHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMW 123 Query: 141 SIGRE-----NYNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTE 181 R D NRNF + S P ET A+ +++ Sbjct: 124 RKTRSTNAGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNN 183 Query: 182 TFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKG 239 + A ++H + YP+ Y L ++ LA + Sbjct: 184 LSSIKAYLSIHSYSQHIVYPYS---------YDYKLPENNAELNNLAKAAVKELATLY-- 232 Query: 240 DECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282 K + G T + Y GG D+ Y + T EL Sbjct: 233 ---GTKYTYGPGAT---TLYLAPGGGDDWAYDQGIKYSFTFEL 269 >2BOA-A nrPDB Length = 404 Score = 250 bits (637), Expect = 1e-66, Method: Composition-based stats. Identities = 58/287 (20%), Positives = 104/287 (36%), Gaps = 43/287 (14%) Query: 19 DFNYHRQEGMEAF---LKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75 +FNY +EA + +A ++ + IG S + R ++VL + P Sbjct: 100 NFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFST---GKGVRRPA 156 Query: 76 FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135 A +H E + + + +V+ +DP IT+++ I ++P NPDG+ + Sbjct: 157 VWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQT 216 Query: 136 PDCYYSIGR-----ENYNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMK 176 + + R + D NRN+ +F S P E +V+ Sbjct: 217 QNRLWRKTRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVD 276 Query: 177 WLKTET-FVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPN 235 +++ F +LH + + YP+ YS PD + +A A + Sbjct: 277 FIQKHGNFKGFIDLHSYSQLLMYPYG---------YSVKKAPDAEELDKVARLAAKALAS 327 Query: 236 MKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282 + + T + YP G D+ Y F T EL Sbjct: 328 V-----SGTEYQVGPTCT---TVYPASGSSIDWAYDNGIKFAFTFEL 366 >4BD9-A nrPDB Length = 310 Score = 248 bits (633), Expect = 3e-66, Method: Composition-based stats. Identities = 58/287 (20%), Positives = 104/287 (36%), Gaps = 43/287 (14%) Query: 19 DFNYHRQEGMEAF---LKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75 +FNY +EA + +A ++ + IG S + R ++VL + P Sbjct: 6 NFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFST---GKGVRRPA 62 Query: 76 FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135 A +H E + + + +V+ +DP IT+++ I ++P NPDG+ + Sbjct: 63 VWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQT 122 Query: 136 PDCYYSIGR-----ENYNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMK 176 + + R + D NRN+ +F S P E +V+ Sbjct: 123 QNRLWRKTRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVD 182 Query: 177 WLKTET-FVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPN 235 +++ F +LH + + YP+ YS PD + +A A + Sbjct: 183 FIQKHGNFKGFIDLHSYSQLLMYPYG---------YSVKKAPDAEELDKVARLAAKALAS 233 Query: 236 MKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282 + + T + YP G D+ Y F T EL Sbjct: 234 V-----SGTEYQVGPTCT---TVYPASGSSIDWAYDNGIKFAFTFEL 272 >3V7Z-A nrPDB Length = 326 Score = 242 bits (618), Expect = 2e-64, Method: Composition-based stats. Identities = 78/327 (23%), Positives = 129/327 (39%), Gaps = 50/327 (15%) Query: 17 ALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEF 76 + D YH M + TVA NY ++ SIGKS +GR LW + + PE Sbjct: 4 SYDSGYHNYNEMVNKINTVASNYPNIVKKFSIGKSYEGRELWAVKISDNVGTDE-NEPEV 62 Query: 77 KYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKP 136 Y A H E + E+ L+ +D + D ITNL+N+ I+I+ ++NPDG E Sbjct: 63 LYTALHHAREHLTVEMALYTLDLFTQNYNLDSRITNLVNNREIYIVFNINPDGGEYDISS 122 Query: 137 DCY--YSIGR-----ENYNQYDLNRNF---------------PDAFEYNNVSRQPETVAV 174 Y + R +Y DLNRN+ + + + PET A+ Sbjct: 123 GSYKSWRKNRQPNSGSSYVGTDLNRNYGYKWGCCGGSSGSPSSETYRGRSAFSAPETAAM 182 Query: 175 MKWLKTETFVLSANLHGGALVASYPFDNGV-QATGALYS---RSLTPDD-DVFQYLAHTY 229 ++ + V+ L+ + + + G Y+ +T DD +VF+ +A+T Sbjct: 183 RDFINSR--VVGGKQQIKTLITFHTYSELILYPYGYTYTDVPSDMTQDDFNVFKTMANTM 240 Query: 230 ASRNPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCK--- 286 A N + Y G M D+ Y + F T E+ Sbjct: 241 AQTNGYTPQ---------------QASDLYITDGDMTDWAYGQHKIFAFTFEMYPTSYNP 285 Query: 287 --YPREEKLPSFWNNNKASLIEYIKQV 311 YP +E + + NK +++ ++ Sbjct: 286 GFYPPDEVIGRETSRNKEAVLYVAEKA 312 >1AYE-A nrPDB Length = 401 Score = 238 bits (608), Expect = 3e-63, Method: Composition-based stats. Identities = 63/314 (20%), Positives = 110/314 (35%), Gaps = 51/314 (16%) Query: 18 LDFN-YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEF 76 +F YH E + + + + + +IG S + R + VL P Sbjct: 100 FNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD-----KPAI 154 Query: 77 KYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKP 136 A +H E V + L + +V+ GKDP IT+++++ I ++P NPDG+ + Sbjct: 155 WLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTK 214 Query: 137 DCYYSIGREN-----YNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKW 177 + + R D NRN+ F S P E +++ + Sbjct: 215 NRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDF 274 Query: 178 LKTETFV-LSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNM 236 +K+ V LH + + +P+ Y + D D +A A ++ Sbjct: 275 IKSHGKVKAFIILHSYSQLLMFPYG---------YKCTKLDDFDELSEVAQKAAQSLRSL 325 Query: 237 KKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCC-KY----PREE 291 K + Y GG D++Y + + EL +Y P + Sbjct: 326 H-----GTKYKVGPICS---VIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQ 377 Query: 292 KLP---SFWNNNKA 302 LP W KA Sbjct: 378 ILPTAEETWLGLKA 391 >1DTD-A nrPDB Length = 303 Score = 237 bits (604), Expect = 9e-63, Method: Composition-based stats. Identities = 63/315 (20%), Positives = 109/315 (34%), Gaps = 52/315 (16%) Query: 18 LDFN-YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEF 76 +F YH E + + + + + +IG S + R + VL P Sbjct: 1 FNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD-----KPAI 55 Query: 77 KYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKP 136 A +H E V + L + +V+ GKDP IT+++++ I ++P NPDG+ + Sbjct: 56 WLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTK 115 Query: 137 DCYYSIGREN------YNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMK 176 + + R D NRN+ F S P E +++ Sbjct: 116 NRMWRKTRSKVSAGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVD 175 Query: 177 WLKTETFV-LSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPN 235 ++K+ V LH + + +P+ Y + D D +A A Sbjct: 176 FIKSHGKVKAFIILHSYSQLLMFPYG---------YKCTKLDDFDELSEVAQKAAQSLSR 226 Query: 236 MKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCC-KY----PRE 290 + K + Y GG D++Y + + EL +Y P Sbjct: 227 LH-----GTKYKVGPICS---VIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPAR 278 Query: 291 EKLP---SFWNNNKA 302 + LP W KA Sbjct: 279 QILPTAEETWLGLKA 293 >3D68-A nrPDB Length = 424 Score = 235 bits (598), Expect = 5e-62, Method: Composition-based stats. Identities = 55/289 (19%), Positives = 104/289 (35%), Gaps = 41/289 (14%) Query: 16 AALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75 A+ YH + ++++ + + + + IG S + L+VL V + + Sbjct: 118 ASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVS---GKEQTAKNA 174 Query: 76 FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135 +H E + L I ++ G + TNL+ ++MP +N DG++ K Sbjct: 175 IWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWK 234 Query: 136 PDCYYSIGRENYN-----QYDLNRNF---------------PDAFEYNNVSRQPETVAVM 175 + + R Y DLNRNF + + +PE AV Sbjct: 235 KNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVA 294 Query: 176 KWLKTETFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRN 233 +L+ + A ++H + +P+ Y+RS + D + +A Sbjct: 295 SFLRRNINQIKAYISMHSYSQHIVFPYS---------YTRSKSKDHEELSLVASEAVRAI 345 Query: 234 PNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282 + K + + G + Y GG D+ Y + T+EL Sbjct: 346 EKISKN------IRYTYG-QGSETLYLAPGGGDDWIYDLGIKYSFTIEL 387 >3LMS-A nrPDB Length = 309 Score = 233 bits (594), Expect = 1e-61, Method: Composition-based stats. Identities = 55/289 (19%), Positives = 103/289 (35%), Gaps = 41/289 (14%) Query: 16 AALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75 A+ YH + ++++ + + + + IG S + L+VL V + + Sbjct: 3 ASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVS---GKEQAAKNA 59 Query: 76 FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135 +H E + L I ++ G + TNL+ ++MP +N DG++ K Sbjct: 60 IWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWK 119 Query: 136 PDCYYSIGRENYN-----QYDLNRNF---------------PDAFEYNNVSRQPETVAVM 175 + + R Y DLNRNF + + +PE AV Sbjct: 120 KNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVA 179 Query: 176 KWLKTETFVLSA--NLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRN 233 +L+ + A ++H + +P+ Y+RS + D + +A Sbjct: 180 SFLRRNINQIKAYISMHSYSQHIVFPYS---------YTRSKSKDHEELSLVASEAVRAI 230 Query: 234 PNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282 K + +G + Y GG D+ Y + T+EL Sbjct: 231 EKTSKNT------RYTHGH-GSETLYLAPGGGDDWIYDLGIKYSFTIEL 272 >3KGQ-A nrPDB Length = 309 Score = 223 bits (567), Expect = 2e-58, Method: Composition-based stats. Identities = 51/281 (18%), Positives = 95/281 (33%), Gaps = 41/281 (14%) Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81 YH + + F+ + + + IG+S +GR ++VL P Sbjct: 12 YHTLDEIYDFMDLLVAEHPQLVSKLQIGRSYEGRPIYVLKFSTGGSNR----PAIWIDLG 67 Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141 +H E + + + G+DP T +++S I + NPDGF + + Sbjct: 68 IHSREWITQATGVWFAKKFTEDYGQDPSFTAILDSMDIFLEIVTNPDGFAFTHSQNRLWR 127 Query: 142 IGR-----ENYNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTET 182 R D NRN+ F S P E +++ ++K Sbjct: 128 KTRSVTSSSLCVGVDANRNWDAGFGKAGASSSPCSETYHGKYANSEVEVKSIVDFVKDHG 187 Query: 183 -FVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDE 241 F ++H + + YP+ Y+ PD +A + ++ Sbjct: 188 NFKAFLSIHSYSQLLLYPYG---------YTTQSIPDKTELNQVAKSAVEALKSLY---- 234 Query: 242 CKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282 + + +T + Y GG D++Y + T EL Sbjct: 235 -GTSYKYGSIIT---TIYQASGGSIDWSYNQGIKYSFTFEL 271 >5OM9-A nrPDB Length = 419 Score = 215 bits (546), Expect = 5e-56, Method: Composition-based stats. Identities = 51/281 (18%), Positives = 94/281 (33%), Gaps = 41/281 (14%) Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81 YH E + FL + + IG + +GR ++VL P Sbjct: 122 YHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTG----GSKRPAIWIDTG 177 Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141 +H E V + + + G+D T ++++ I + NPDGF + + Sbjct: 178 IHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWR 237 Query: 142 IGREN-----YNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTET 182 R + D NRN+ F + S P E +++ ++K Sbjct: 238 KTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHG 297 Query: 183 FV-LSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDE 241 + ++H + + YP+ Y PD D L+ + ++ Sbjct: 298 NIKAFISIHSYSQLLMYPYG---------YKTEPVPDQDELDQLSKAAVTALASLY---- 344 Query: 242 CKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282 K N+ + + + Y G D+ Y + T EL Sbjct: 345 -GTKFNYGSII---KAIYQASGSTIDWTYSQGIKYSFTFEL 381 >4UEE-A nrPDB Length = 309 Score = 212 bits (539), Expect = 3e-55, Method: Composition-based stats. Identities = 51/281 (18%), Positives = 94/281 (33%), Gaps = 41/281 (14%) Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81 YH E + FL + + IG + +GR ++VL P Sbjct: 12 YHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTG----GSKRPAIWIDTG 67 Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141 +H E V + + + G+D T ++++ I + NPDGF + + Sbjct: 68 IHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWR 127 Query: 142 IGREN-----YNQYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTET 182 R + D NRN+ F + S P E +++ ++K Sbjct: 128 KTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHG 187 Query: 183 FV-LSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDE 241 + ++H + + YP+ Y PD D L+ + ++ Sbjct: 188 NIKAFISIHSYSQLLMYPYG---------YKTEPVPDQDELDQLSKAAVTALASLY---- 234 Query: 242 CKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282 K N+ + + + Y G D+ Y + T EL Sbjct: 235 -GTKFNYGSII---KAIYQASGSTIDWTYSQGIKYSFTFEL 271 >1PCA-A nrPDB Length = 403 Score = 211 bits (538), Expect = 4e-55, Method: Composition-based stats. Identities = 46/281 (16%), Positives = 96/281 (34%), Gaps = 41/281 (14%) Query: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81 YH E + F+ + + ++ IG+S +GR ++VL P + Sbjct: 107 YHTLEEIYDFMDILVAEHPALVSKLQIGRSYEGRPIYVLKFSTGGSNR----PAIWIDSG 162 Query: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141 +H E + + + + + G++ T +++S I + NP+GF + + Sbjct: 163 IHSREWITQASGVWFAKKITENYGQNSSFTAILDSMDIFLEIVTNPNGFAFTHSDNRLWR 222 Query: 142 IGRENYN-----QYDLNRNFPDAFEYNNVSRQP--------------ETVAVMKWLKTET 182 R + D NRN+ F S P E ++ ++K Sbjct: 223 KTRSKASGSLCVGSDSNRNWDAGFGGAGASSSPCAETYHGKYPNSEVEVKSITDFVKNNG 282 Query: 183 FV-LSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDE 241 + ++H + + YP+ Y D +A + + ++ Sbjct: 283 NIKAFISIHSYSQLLLYPYG---------YKTQSPADKSELNQIAKSAVAALKSLY---- 329 Query: 242 CKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282 + + +T Y GG+ D+ Y + + EL Sbjct: 330 -GTSYKYGSIIT---VIYQASGGVIDWTYNQGIKYSFSFEL 366 >1JQG-A nrPDB Length = 433 Score = 203 bits (515), Expect = 2e-52, Method: Composition-based stats. Identities = 66/283 (23%), Positives = 103/283 (36%), Gaps = 44/283 (15%) Query: 23 HRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANM 82 H E ++A+L+ +A+ + +V + GKS +GR++ L + P + + Sbjct: 122 HSYEEVDAYLQELAKEFPNVVTVVEGGKSFEGRSIKYLRIST-TNFQDASKPVVMMQSLL 180 Query: 83 HGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSI 142 H E V L+ I LV D ++LIN+ I+P NPDG+ D Y+ Sbjct: 181 HCREWVTLPATLYAIHKLVI----DVTESDLINNIDWIILPVANPDGYVHTFGGDRYWRK 236 Query: 143 GRENYN-------QYDLNRNF-------------PDAFEYNNVSRQPETVAVMKWL--KT 180 R DLNRNF D F + +PE+ + + Sbjct: 237 NRATGYMAGNLCMGVDLNRNFGMNWGTASSSSVCSDTFHGRSAFSEPESSVIRDIIAEHR 296 Query: 181 ETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD 240 L ++H + Y + NGV + AL + A +K Sbjct: 297 NRMALYLDIHSFGSMILYGYGNGVLPSNAL----------QLHLIGVQMAQAIDRVKWSS 346 Query: 241 ECKNKMNFPNGVTNGYS-WYPLQGGMQDYNYIWAQCFEITLEL 282 K+ + V N + Y GG DY A F T EL Sbjct: 347 N-KDYI-----VGNIFHVLYAASGGASDYAMQAAAPFSYTYEL 383 >5MRV-A nrPDB Length = 355 Score = 197 bits (501), Expect = 7e-51, Method: Composition-based stats. Identities = 43/290 (14%), Positives = 97/290 (33%), Gaps = 42/290 (14%) Query: 15 VAALDFN-YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGI 73 + +N YH + +++ +++ Y V H +G + + ++ L + + Sbjct: 48 LETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPIYYLKISQPSGN---PK 104 Query: 74 PEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAV 133 +H E + + ++ + + I L+ + +++P +N DG+ Sbjct: 105 KIIWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSRIRKLLRNLDFYVLPVLNIDGYIYT 164 Query: 134 KKPDCYYSIGRENYN-----QYDLNRNFPDAFEYNNVSRQ--------------PETVAV 174 D + R +N DLNRNF ++ SR PET AV Sbjct: 165 WTTDRLWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAV 224 Query: 175 MKWLKTETFVL--SANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASR 232 +++++ + +H + P+ Y+++ + + + A+ Sbjct: 225 ASFIESKKDDILCFLTMHSYGQLILTPYG---------YTKNKSSNHPEMIQVGQKAANA 275 Query: 233 NPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282 ++ Y G +D+ F T EL Sbjct: 276 LKAKY-----GTNYRVG---SSADILYASSGSSRDWARDIGIPFSYTFEL 317 >3K2K-A nrPDB Length = 403 Score = 175 bits (443), Expect = 3e-44, Method: Composition-based stats. Identities = 57/293 (19%), Positives = 107/293 (36%), Gaps = 42/293 (14%) Query: 20 FNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79 F + +E FL V Q + +G++V+GR + ++V+G P E + + Sbjct: 130 FEPYSEERHSEFLGAVQQM--PQASVVELGRTVEGRPMSLVVLGT-PDEAGAAKKKVWII 186 Query: 80 ANMHGDETVGRELLLHLIDYLVTSD--GKDPEITNLINSTRIHIMPSMNPDGFEAVKKPD 137 A H E++ + L+ LV DP L + +I+P+MNPDG Sbjct: 187 ARQHPGESMAEWFIEGLVKRLVGWGDWSGDPVARKLYDHATFYIVPNMNPDG-------- 238 Query: 138 CYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVAS 197 + R N +LNR + + R PE + V + L ++HG Sbjct: 239 SVHGNLRTNAAGANLNREW----MEPDAERSPEVLVVRDAIHAIGCDLFFDIHG------ 288 Query: 198 YPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYS 257 + + P Q + + A + + + +++ +P G + Sbjct: 289 ----DEDLPYVFAAGSEMLPGFTEQQRVEQS-AFIDSFKRASPDFQDEHGYPPGKYREDA 343 Query: 258 WYPLQGGMQDYNYIWAQ--CFEITLELSCCKYPREEKLPSF---WNNNKASLI 305 + YI + C +TLE+ + LP WN +++ + Sbjct: 344 FKLASK------YIGHRFGCLSLTLEM---PFKDNANLPDEHIGWNGARSASL 387 >1CPB-B nrPDB Length = 217 Score = 171 bits (432), Expect = 7e-43, Method: Composition-based stats. Identities = 36/197 (18%), Positives = 67/197 (34%), Gaps = 38/197 (19%) Query: 107 DPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGREN-----YNQYDLNRNFPDAFE 161 + +T ++ +++P +N DG+ + + R DLNRNF + Sbjct: 1 EIHMTEFLDKLDFYVLPVVNIDGYIYTWTTNRMWRKTRSTRAGSSCTGTDLNRNFDAGWC 60 Query: 162 YNNVSRQP--------------ETVAVMKWLKTETFVLSA--NLHGGALVASYPFDNGVQ 205 S P E+ AV +++ + A +H + + YP+ Sbjct: 61 SIGASNNPCSETYCGSAAESEKESKAVADFIRNHLSSIKAYLTIHSYSQMMLYPYS---- 116 Query: 206 ATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGM 265 Y L ++ LA + ++ ++ G T + YP GG Sbjct: 117 -----YDYKLPKNNVELNTLAKGAVKKLASLH-----GTTYSYGPGAT---TIYPASGGS 163 Query: 266 QDYNYIWAQCFEITLEL 282 D+ Y + T EL Sbjct: 164 DDWAYDQGIKYSFTFEL 180 >4B6Z-A nrPDB Length = 405 Score = 166 bits (420), Expect = 2e-41, Method: Composition-based stats. Identities = 42/174 (24%), Positives = 71/174 (40%), Gaps = 17/174 (9%) Query: 20 FNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79 F + +E AFL V Q + +G++V+GR + +L +G P+ + + Sbjct: 132 FEPYSEERHAAFLGAVQQL--PQASVVELGRTVEGRPMSLLTLGT-PETDGAPKKKVWII 188 Query: 80 ANMHGDETVGRELLLHLIDYLVTSD--GKDPEITNLINSTRIHIMPSMNPDGFEAVKKPD 137 A H E++ + L+ L DP L + HI+P+MNPDG Sbjct: 189 ARQHPGESMAEWFVEGLVKRLAGWGDWAGDPVARKLYDRVTFHIVPNMNPDG-------- 240 Query: 138 CYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHG 191 + R N +LNR + + R PE +AV + + ++HG Sbjct: 241 SVHGNLRTNAAGANLNREWMA----PDAERSPEVLAVRDAIHAIGCDMFFDIHG 290 >2C1C-A nrPDB Length = 312 Score = 165 bits (418), Expect = 3e-41, Method: Composition-based stats. Identities = 54/290 (18%), Positives = 97/290 (33%), Gaps = 43/290 (14%) Query: 17 ALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEF 76 D NY E ++ +L + + Y V + + +S +GR + + + E P Sbjct: 2 PYD-NYQELEVIDEYLDYIGEKYPDVATVVNAAESFEGRPIKYIKISTTNFEDE-NKPVI 59 Query: 77 KYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKP 136 +H E + + I LV D +L+ ++P +NPDG++ Sbjct: 60 FIDGGIHAREWISPPSVTWAIHKLVE----DVTENDLLEKFDWILLPVVNPDGYKYTFTN 115 Query: 137 DCYYSIGRENYN--------QYDLNRNFP--------------DAFEYNNVSRQPETVAV 174 + ++ R N D NRNF D + + + ET V Sbjct: 116 ERFWRKTRSTNNNPLSQICRGADGNRNFDFVWNSIGTSNSPCSDIYAGTSAFSEVETRVV 175 Query: 175 MKWLKTE--TFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASR 232 L L +H + YP+ + G+L +L HT Sbjct: 176 RDILHEHLARMALYLTMHSFGSMILYPWGHD----GSLSQNALG---------LHTVGVA 222 Query: 233 NPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 282 ++ + + N + G + Y + G +DY + T EL Sbjct: 223 MASVIQSNALPNFPPYTVGNSALVIGYYIAGSSEDYAHSIGVPLSYTYEL 272 >4A39-A nrPDB Length = 388 Score = 152 bits (385), Expect = 2e-37, Method: Composition-based stats. Identities = 43/172 (25%), Positives = 73/172 (42%), Gaps = 20/172 (11%) Query: 20 FNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV 79 F + +E ++ ++G SV+GR++ +L V R P H + + Sbjct: 123 FEPYSRERHARLVERALGIEG--VERLAVGTSVQGRDIELLRVRRHPDSHL----KLWVI 176 Query: 80 ANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCY 139 A H E + + LI+ L D D E+ L+ ++++P+MNPDG + Sbjct: 177 AQQHPGEHMAEWFMEGLIERLQRPD--DTEMQRLLEKADLYLVPNMNPDG--------AF 226 Query: 140 YSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHG 191 + R N DLNR A+ + R PE V + +K L ++HG Sbjct: 227 HGNLRTNAAGQDLNR----AWLEPSAERSPEVWFVQQEMKRHGVDLFLDIHG 274 >3L2N-A nrPDB Length = 395 Score = 121 bits (303), Expect = 6e-28, Method: Composition-based stats. Identities = 37/177 (20%), Positives = 69/177 (38%), Gaps = 20/177 (11%) Query: 15 VAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIP 74 + F + E + V + + +G ++ GR++ ++ VG Sbjct: 123 IQIAYFTPYSYERHLDLISAVQ-LHP-LVSTEHLGLTLDGRDMTLVKVGD----DDPSKK 176 Query: 75 EFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVK 134 A H ET+ L+ L++ L+ +D P L++ +I+P+MNPDG Sbjct: 177 SIWITARQHPGETMAEWLVEGLLNQLLDNDC--PTSKALLDKANFYIVPNMNPDG----- 229 Query: 135 KPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHG 191 R N +LNR + + ++ R PE V+ + L ++HG Sbjct: 230 ---SVRGHLRTNAVGANLNREW----QTPSLERSPEVYYVVNKMHETGVDLFYDVHG 279 >1CPB-A nrPDB Length = 82 Score = 92.9 bits (229), Expect = 3e-19, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 28/79 (35%), Gaps = 4/79 (5%) Query: 21 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 80 Y+ E +EA+ + VA + +IG + G +++L VG+ P Sbjct: 8 KYNNWETIEAWTEQVASENPDLISRSAIGTTFLGNTIYLLKVGKPGSNK----PAVFMDC 63 Query: 81 NMHGDETVGRELLLHLIDY 99 H E + + Sbjct: 64 GFHAREWISPAFCQWFVRE 82 >5AQ0-A nrPDB Length = 82 Score = 90.2 bits (222), Expect = 2e-18, Method: Composition-based stats. Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 4/69 (5%) Query: 314 GVKGQVFDQ-NGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDP- 371 GVKG V D G+ L N + V H T ++G++Y LL+PG+Y + V + G+ P Sbjct: 2 GVKGFVKDSITGSGLENATISVAGINH--NITTGRFGDFYRLLVPGTYNLTVVLTGYMPL 59 Query: 372 HITKVIIPE 380 +T V++ E Sbjct: 60 TVTNVVVKE 68 >2QVP-A nrPDB Length = 275 Score = 50.9 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 28/143 (19%), Positives = 47/143 (32%), Gaps = 28/143 (19%) Query: 43 THLHSIGKSVKGR----NLWVLVVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLID 98 T +G + G+ L++L + G+P A HG+E+ G LLH + Sbjct: 35 TERLGLGSKILGQAGHHPLYLLQ----SPGQKAGLPNLLISAGFHGEESAGPWGLLHFLS 90 Query: 99 YLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNF-- 156 L L + ++P +NP GF R N + NR F Sbjct: 91 QLDG---------ELFKRVNLSVLPLVNPTGFAKGH---------RFNELGENPNRGFFI 132 Query: 157 PDAFEYNNVSRQPETVAVMKWLK 179 + E +++ Sbjct: 133 ENGKAKPGADTSAEGRILLEHAH 155 >3B2Y-A nrPDB Length = 275 Score = 48.6 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 46/283 (16%), Positives = 86/283 (30%), Gaps = 37/283 (13%) Query: 26 EGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANMHGD 85 ++AF +A+ + + + SV + + R +P + HG+ Sbjct: 23 NDIDAFYAQLAEEVNRLGLKKNTLGSVDSFAINLYQ----SASQRSDLPSLLISSGFHGE 78 Query: 86 ETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRE 145 E G +LH + L L + ++P +NP GF+A + + + Sbjct: 79 EAAGPWGMLHFLRGLQ---------PALFERVNLSLLPLVNPTGFKAGHRFNRF------ 123 Query: 146 NYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQ 205 + NR F T K L +L A G L ++ + Sbjct: 124 ---GENPNRGFTLENGKPT--PNEHTSLEGKLLLEHAQLLCAASRDGILTC---HEDVLM 175 Query: 206 ATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGM 265 +YS T F K + P VT+G + Sbjct: 176 NETYVYSFEPTQTPGRFSLGLR---DALGQYFKLAKDGFIDECP--VTDGVIFNHFDTSF 230 Query: 266 QDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYI 308 + + +C + P +E N A++ ++I Sbjct: 231 EAFLVRSGAKLA-----ACSETPGQEDFDRRVQANSAAMGQFI 268 >5HXD-A nrPDB Length = 237 Score = 47.1 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 34/166 (20%), Positives = 51/166 (30%), Gaps = 49/166 (29%) Query: 47 SIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGK 106 G+S+ G L +E + +A HGDE L + L S + Sbjct: 19 HYGRSLLGAPLIWFPAPAASRESGL------ILAGTHGDENSSVVTLSCALRTLTPSLRR 72 Query: 107 DPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDA------- 159 H++ +NPDG + R N N DLNRNFP A Sbjct: 73 H------------HVVLCVNPDGCQLG---------LRANANGVDLNRNFPAANWKEGET 111 Query: 160 ---------------FEYNNVSRQPETVAVMKWLKTETFVLSANLH 190 + +PET A+ + + + H Sbjct: 112 VYRWNSAAEERDVVLLTGDKPGSEPETQALCQLIHRIQPAWVVSFH 157 >3IEH-A nrPDB Length = 276 Score = 45.1 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 21/87 (24%), Positives = 33/87 (37%), Gaps = 18/87 (20%) Query: 70 RIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDG 129 + G+P A HG+E+ G LLH + +L + ++P +NP G Sbjct: 63 KSGLPSLLISAGFHGEESAGPWGLLHFLSEAS---------ADLFERVNLSLLPLVNPTG 113 Query: 130 FEAVKKPDCYYSIGRENYNQYDLNRNF 156 F + R N + NR F Sbjct: 114 F------SRGH---RFNKYGENPNRGF 131 >4OKO-A nrPDB Length = 312 Score = 40.9 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 34/168 (20%), Positives = 60/168 (35%), Gaps = 31/168 (18%) Query: 25 QEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANMHG 84 Q+ E + + ++ + + V L+ L K P +HG Sbjct: 33 QQEAEKKILALVSDF-DIDEYGQLDYPVGSYKLYALK----TKNWDASKPYVLVTGGVHG 87 Query: 85 DETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGR 144 ET G + + +D I I+P ++P G+E +I R Sbjct: 88 YETSGVQGAISFAQTRALEFARD---------YNIVILPCLSPWGYE---------TINR 129 Query: 145 ENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTET--FVLSANLH 190 N N D NR+F + + E V MK++ + F++ +LH Sbjct: 130 WNPNALDPNRSF---YLESGCQ---EAVLAMKYVFSLGVEFLMHIDLH 171 >2QJ8-A nrPDB Length = 332 Score = 37.0 bits (84), Expect = 0.014, Method: Composition-based stats. Identities = 32/166 (19%), Positives = 48/166 (28%), Gaps = 37/166 (22%) Query: 53 KGRNLWVLVVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITN 112 KG + L + F G P HG+E G L LV + Sbjct: 26 KGADCEALSLPVFSCNRGEG-PSLLITGGNHGNELQGPI----LARRLVKWLPEAQRCG- 79 Query: 113 LINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRENYN-QYDLNRNFPDAFEYNNVSRQPET 171 RI I+P +NP + R +LNR FP + + R Sbjct: 80 -----RIIIVPEINP---------LAVQAWTRNTPIDGKNLNRVFPGRSDGSVSER---- 121 Query: 172 VAVMKWLKTET---FVLSANLHGGA-------LVASYPFDNGVQAT 207 + + +LH + S+P + Q T Sbjct: 122 --IADAISRLLLPVVDTVLDLHSFGPTWDCAPSIISHPIADIDQMT 165 >4RWR-A nrPDB Length = 331 Score = 36.3 bits (82), Expect = 0.025, Method: Composition-based stats. Identities = 21/108 (19%), Positives = 35/108 (32%), Gaps = 6/108 (5%) Query: 287 YPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTN 346 Y +E+L W NN + ++ I++ GQV G P+ RT Sbjct: 124 YKSKEELKKQWGNNYENNLKKIEEAVSKTAGQVLTYEGKPISASFFSTS------NGRTE 177 Query: 347 KYGEYYLLLLPGSYIINVTVPGHDPHITKVIIPEKSQNFSALKKDILL 394 +Y+ P ++ P T I + L +L Sbjct: 178 NAADYWGNDYPYLKSVDSPWDQASPKFTSEQIFTVADFQKRLGVKVLA 225 >4AXV-A nrPDB Length = 243 Score = 35.9 bits (81), Expect = 0.035, Method: Composition-based stats. Identities = 32/116 (27%), Positives = 37/116 (31%), Gaps = 27/116 (23%) Query: 42 VTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLV 101 + S GKSV G L + +A HGDET L + L Sbjct: 20 LITPTSYGKSVLGAPLLYFPAQVESNSRGL------ILAGTHGDETASIAGLSCALRSLP 73 Query: 102 TSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFP 157 K I SMNPD + R N NQ DLNR FP Sbjct: 74 AECLKHDVIL------------SMNPDANQLG---------TRANANQVDLNRAFP 108 >2OKL-A nrPDB Length = 185 Score = 33.6 bits (75), Expect = 0.20, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 27/72 (37%), Gaps = 7/72 (9%) Query: 319 VFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVII 378 V D +G + + + H + GE G ++ VPG+ P T++ + Sbjct: 78 VTDADGTLYSHALFNPKIISHSVERTYLQGGE-------GCLSVDREVPGYVPRYTRITV 130 Query: 379 PEKSQNFSALKK 390 S N +K Sbjct: 131 KATSINGEEVKL 142 >5OCR-A nrPDB Length = 286 Score = 32.0 bits (71), Expect = 0.53, Method: Composition-based stats. Identities = 27/188 (14%), Positives = 55/188 (29%), Gaps = 29/188 (15%) Query: 4 PCLWLGLLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGR--NLWVLV 61 P WL + D++ E + + + V +G +++ + Sbjct: 117 PSFWL------YSDFDYSVANGETVYSEIDVVELQQFDW---------YEGHQDDIYDMD 161 Query: 62 VGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHI 121 + G M+ E + + G + +I ++ Sbjct: 162 LNLHAVVKENGQ-GVWKRPKMYPQEQLNKWRAPWDPSKDFHIYGCEVNQNEII----WYV 216 Query: 122 MPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVA-VMKWLKT 180 DG E +KP+ Y+ L + F F+ N + PET A + L Sbjct: 217 ------DGVEVARKPNKYWHRPMNVTLSLGLRKPFVKFFDNKNNAINPETDAKAREKLSD 270 Query: 181 ETFVLSAN 188 + + Sbjct: 271 IPTSMYVD 278 >5JBE-A nrPDB Length = 854 Score = 31.3 bits (69), Expect = 0.79, Method: Composition-based stats. Identities = 21/162 (12%), Positives = 48/162 (29%), Gaps = 7/162 (4%) Query: 124 SMNPDGFEAVKKPDCYYSIGRENYNQYD---LNRNFPDAFEYNNVSRQPETVAVMKWLKT 180 +++ D V G +Y + +NR + NN PE + + Sbjct: 160 TIDSDQVIFVNNNSKDPRKGNTSYADSNYRLMNRTINNQAGNNNSDNSPELLVGNDIDNS 219 Query: 181 ETFVLSANLHGGALVASY----PFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNM 236 V + NL+ + +Y ++ G + D DV + Sbjct: 220 NPVVQAENLNWEYFLLNYGKLMGYNPDGNFDGFRVDAADNIDADVLDQMGQLMNDMYHTK 279 Query: 237 KKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEI 278 + +++ G +G + + G + + + Sbjct: 280 GNPQNANDHLSYNEGYHSGAAQMLNEKGNPQLYMDSGEFYTL 321 >5VOC-B nrPDB Length = 278 Score = 30.9 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 25/80 (31%), Gaps = 16/80 (20%) Query: 6 LWLGLLLPLV--AALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKG-------RN 56 LW LLLP+V AA+ E V +T +G+ +G R Sbjct: 19 LWCCLLLPIVSSAAVSVAPTAAE-------KVPAECPELTRRCLLGEVFEGDKYESWLRP 71 Query: 57 LWVLVVGRFPKEHRIGIPEF 76 L + P I Sbjct: 72 LVNVTGRDGPLSQLIRYRPV 91 >3A22-A nrPDB Length = 614 Score = 30.5 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 20/123 (16%), Positives = 37/123 (30%), Gaps = 23/123 (18%) Query: 72 GIPEFKYVAN---MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSM--- 125 G P + N + + L + G P +T+L+++ + P+ Sbjct: 172 GRPLTLSICNWGYQNPWNWAAGQAPLWRTSTDIIYYGNQPSMTSLLSNFDQTLHPTAQHT 231 Query: 126 ----NP-------DGFEAVKKPDCYYSIGRENY---NQYDLNRNFPDAFEYNNVSRQPET 171 +P DGF A + DL + + + PE Sbjct: 232 GYYNDPDMLMVGMDGFTAAQNRTHMNLWAISGAPLLAGNDLTTMTSETA---GILKNPEV 288 Query: 172 VAV 174 +AV Sbjct: 289 IAV 291 >2AZQ-A nrPDB Length = 311 Score = 29.7 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 14/36 (38%), Positives = 17/36 (47%), Gaps = 3/36 (8%) Query: 315 VKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGE 350 ++GQVFD NG PL V D H T Y + Sbjct: 135 LQGQVFDANGKPLAGATV---DLWHANTQGTYSYFD 167 >3ZHL-A nrPDB Length = 127 Score = 29.3 bits (64), Expect = 3.2, Method: Composition-based stats. Identities = 9/81 (11%), Positives = 24/81 (29%), Gaps = 11/81 (13%) Query: 230 ASRNPNMKKGDECKNKMNFPNGVTNGYSWY---------PLQGGMQDYNYIWAQ--CFEI 278 + +++ + + G +WY + ++ Y+ E Sbjct: 31 SYAMGWVRQAPGKGPEWVSLISGSGGSTWYDDSVKGRFTISRDNSKNLLYLQMNSLRAED 90 Query: 279 TLELSCCKYPREEKLPSFWNN 299 T C ++ + P +W Sbjct: 91 TAVYYCARHAPSTEAPDYWGQ 111 >4E79-A nrPDB Length = 357 Score = 28.6 bits (62), Expect = 5.3, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 31/81 (38%), Gaps = 2/81 (2%) Query: 299 NNKASLIEYIKQVHLGVKGQVFDQNGNPLPN-VIVEVQDRKHICPYRTNKYGEYYLLLLP 357 +K + HL VKG++ + N +E + H+ K+ + + Sbjct: 2 GSKVQQYRLDELAHL-VKGELIGEGSLQFSNLASLENAEVNHLTFVNGEKHLDQAKVSRA 60 Query: 358 GSYIINVTVPGHDPHITKVII 378 G+YI+ + H P II Sbjct: 61 GAYIVTAALKEHLPEKDNFII 81 >4M1U-A nrPDB Length = 297 Score = 28.6 bits (62), Expect = 5.5, Method: Composition-based stats. Identities = 7/56 (12%), Positives = 22/56 (39%) Query: 327 LPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVIIPEKS 382 + + V + ++ ++ + +PG +++T + +V E+S Sbjct: 71 IEQNNLYVAGFVNTATNTFYRFSDFTHISVPGVTTVSMTTDSSYTTLQRVAALERS 126 >2HN1-A nrPDB Length = 266 Score = 28.6 bits (62), Expect = 6.2, Method: Composition-based stats. Identities = 17/109 (15%), Positives = 36/109 (33%), Gaps = 3/109 (2%) Query: 50 KSVKGRNLWVLVVGRFPKEHRIGIPEFKYV-ANMHGDETVGRELLLHL-IDYLVTSDGKD 107 KSV+ + L V + + + +H DE++ ++ L I L D + Sbjct: 42 KSVEFKELEVGELESVVRSALALNKKLWIDVVGVH-DESLIAKICEFLGIHPLAAEDILN 100 Query: 108 PEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNF 156 I H+ + + + D + ++N R + Sbjct: 101 TAQRVKIEDYDDHLFLVLKILLYNETLEIDQLSLVLKKNLVATFEEREY 149 >1JQP-A nrPDB Length = 438 Score = 27.8 bits (60), Expect = 9.4, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 20/49 (40%), Gaps = 1/49 (2%) Query: 248 FPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSF 296 + G G+ + QD+ + CF T + CK P+E L + Sbjct: 269 YAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCK-PKENCLRYY 316 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.127 0.346 Lambda K H 0.267 0.0393 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,579,089 Number of Sequences: 36641 Number of extensions: 702915 Number of successful extensions: 2064 Number of sequences better than 10.0: 53 Number of HSP's better than 10.0 without gapping: 59 Number of HSP's successfully gapped in prelim test: 40 Number of HSP's that attempted gapping in prelim test: 1812 Number of HSP's gapped (non-prelim): 105 length of query: 443 length of database: 10,336,785 effective HSP length: 100 effective length of query: 343 effective length of database: 6,672,685 effective search space: 2288730955 effective search space used: 2288730955 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 60 (27.8 bits)