BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P14091 (396 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1TZS-A nrPDB 701 0.0 2PSG-A nrPDB 402 e-112 4PEP-A nrPDB 382 e-106 1PSO-E nrPDB 375 e-104 5UX4-A nrPDB 363 e-101 4AA9-A nrPDB 356 1e-98 4CMS-A nrPDB 347 7e-96 1AM5-A nrPDB 336 9e-93 1AVF-A nrPDB 328 3e-90 5N71-A nrPDB 316 1e-86 5MKT-A nrPDB 304 5e-83 5MLG-A nrPDB 297 5e-81 1SMR-A nrPDB 294 4e-80 4AMT-A nrPDB 293 7e-80 5NFG-A nrPDB 287 6e-78 3VCM-A nrPDB 284 4e-77 1FMX-A nrPDB 280 7e-76 4OC6-B nrPDB 269 2e-72 1QDM-A nrPDB 221 5e-58 1B5F-A nrPDB 209 1e-54 2BJU-A nrPDB 176 1e-44 5BWY-A nrPDB 176 2e-44 1XDH-A nrPDB 175 4e-44 1UH8-A nrPDB 174 7e-44 2ANL-A nrPDB 165 3e-41 3QS1-A nrPDB 163 1e-40 1MIQ-A nrPDB 159 2e-39 1QS8-A nrPDB 158 4e-39 5JOD-A nrPDB 157 7e-39 5I70-B nrPDB 157 1e-38 3QVI-A nrPDB 150 6e-37 3FNT-A nrPDB 149 2e-36 3OAD-B nrPDB 147 8e-36 3O9L-A nrPDB 145 2e-35 2ASI-A nrPDB 128 4e-30 3FV3-A nrPDB 127 1e-29 3LIZ-A nrPDB 122 2e-28 1MPP-A nrPDB 120 7e-28 4Y9W-A nrPDB 115 2e-26 3PVK-A nrPDB 115 4e-26 1WKR-A nrPDB 112 2e-25 1J71-A nrPDB 108 4e-24 2QZW-A nrPDB 106 2e-23 4OD9-A nrPDB 105 4e-23 3TPL-A nrPDB 105 5e-23 2H6T-A nrPDB 105 5e-23 2QZX-A nrPDB 100 2e-21 3ZKX-A nrPDB 99 2e-21 4B1C-A nrPDB 96 4e-20 1PPK-E nrPDB 95 5e-20 5HCT-A nrPDB 94 7e-20 3PI0-A nrPDB 94 1e-19 1IBQ-A nrPDB 90 2e-18 1IZE-A nrPDB 84 1e-16 1B5F-B nrPDB 74 1e-13 3EMY-A nrPDB 70 1e-12 4ZL4-A nrPDB 59 5e-09 3CTV-A nrPDB 30 2.6 2C44-A nrPDB 29 3.6 2PQ6-A nrPDB 28 5.1 1IQC-A nrPDB 28 6.8 3FHH-A nrPDB 28 9.1 >1TZS-A nrPDB Length = 351 Score = 701 bits (1810), Expect = 0.0, Method: Compositional matrix adjust. Identities = 343/343 (100%), Positives = 343/343 (100%) Query: 54 IQFTESCSMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPA 113 IQFTESCSMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPA Sbjct: 1 IQFTESCSMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPA 60 Query: 114 CKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPG 173 CKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPG Sbjct: 61 CKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPG 120 Query: 174 QTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIF 233 QTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIF Sbjct: 121 QTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIF 180 Query: 234 GGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDK 293 GGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDK Sbjct: 181 GGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDK 240 Query: 294 IKQLQNAIGAAPVDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSS 353 IKQLQNAIGAAPVDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSS Sbjct: 241 IKQLQNAIGAAPVDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSS 300 Query: 354 GFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPAVP 396 GFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPAVP Sbjct: 301 GFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPAVP 343 >2PSG-A nrPDB Length = 370 Score = 402 bits (1033), Expect = e-112, Method: Compositional matrix adjust. Identities = 204/376 (54%), Positives = 263/376 (69%), Gaps = 11/376 (2%) Query: 21 LHRVPLRRHPSLKKKLRARSQLSEFWKSH--NLDMIQFTESCSMDQSAKEPLINYLDMEY 78 L +VPL R SL++ L +L +F K+H N F E+ ++ EPL NYLD EY Sbjct: 1 LVKVPLVRKKSLRQNLIKDGKLKDFLKTHKHNPASKYFPEAAAL--IGDEPLENYLDTEY 58 Query: 79 FGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSIQ 138 FGTI IG+P Q+FTVIFDTGSSNLWVPSVYC+S AC H++F P SST+ Q SI Sbjct: 59 FGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSLACSDHNQFNPDDSSTFEATSQELSIT 118 Query: 139 YGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVT 198 YGTGS++GI+G D V V G++ Q FG S TEPG A FDGILGL YPS++ G T Sbjct: 119 YGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISASGAT 178 Query: 199 PVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQI 258 PVFDN+ Q LV +FSVY+SSN + +GS ++ GG D S+++GSLNWVPV+ + YWQI Sbjct: 179 PVFDNLWDQGLVSQDLFSVYLSSNDD--SGSVVLLGGIDSSYYTGSLNWVPVSVEGYWQI 236 Query: 259 ALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAP-VDGEYAVECANL 317 LD+I + G + CS GCQAIVDTGTSL+TGP+ I +Q+ IGA+ DGE + C+++ Sbjct: 237 TLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASENSDGEMVISCSSI 296 Query: 318 NVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQ 377 + +PD+ FTI+GV Y LSP+AY L D C+SGF+G+D+ +G LWILGDVFIRQ Sbjct: 297 DSLPDIVFTIDGVQYPLSPSAYILQD----DDSCTSGFEGMDVPTSSGELWILGDVFIRQ 352 Query: 378 FYSVFDRGNNRVGLAP 393 +Y+VFDR NN+VGLAP Sbjct: 353 YYTVFDRANNKVGLAP 368 >4PEP-A nrPDB Length = 326 Score = 382 bits (982), Expect = e-106, Method: Compositional matrix adjust. Identities = 189/329 (57%), Positives = 239/329 (72%), Gaps = 7/329 (2%) Query: 66 AKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQS 125 EPL NYLD EYFGTI IG+P Q+FTVIFDTGSSNLWVPSVYC+S AC H++F P S Sbjct: 2 GDEPLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSLACSDHNQFNPDDS 61 Query: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185 ST+ Q SI YGTGS++GI+G D V V G++ Q FG S TEPG A FDGIL Sbjct: 62 STFEATSQELSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGIL 121 Query: 186 GLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245 GL YPS++ G TPVFDN+ Q LV +FSVY+SSN + +GS ++ GG D S+++GSL Sbjct: 122 GLAYPSISASGATPVFDNLWDQGLVSQDLFSVYLSSNDD--SGSVVLLGGIDSSYYTGSL 179 Query: 246 NWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAP 305 NWVPV+ + YWQI LD+I + G + CS GCQAIVDTGTSL+TGP+ I +Q+ IGA+ Sbjct: 180 NWVPVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASE 239 Query: 306 -VDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPA 364 DGE + C++++ +PD+ FTI+GV Y LSP+AY L D C+SGF+G+D+ + Sbjct: 240 NSDGEMVISCSSIDSLPDIVFTIDGVQYPLSPSAYILQD----DDSCTSGFEGMDVPTSS 295 Query: 365 GPLWILGDVFIRQFYSVFDRGNNRVGLAP 393 G LWILGDVFIRQ+Y+VFDR NN+VGLAP Sbjct: 296 GELWILGDVFIRQYYTVFDRANNKVGLAP 324 >1PSO-E nrPDB Length = 326 Score = 375 bits (963), Expect = e-104, Method: Compositional matrix adjust. Identities = 186/328 (56%), Positives = 240/328 (73%), Gaps = 7/328 (2%) Query: 67 KEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSS 126 ++PL NYLDMEYFGTI IG+P Q+FTV+FDTGSSNLWVPSVYC+S AC H+RF P SS Sbjct: 3 EQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNPEDSS 62 Query: 127 TYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILG 186 TY ++ SI YGTGS++GI+G D V V G++ Q FG S TEPG A FDGILG Sbjct: 63 TYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILG 122 Query: 187 LGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLN 246 L YPS++ G TPVFDN+ Q LV +FSVY+S++ + +GS +IFGG D S+++GSLN Sbjct: 123 LAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQ--SGSVVIFGGIDSSYYTGSLN 180 Query: 247 WVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAP- 305 WVPVT + YWQI +D+I + G + C+EGCQAIVDTGTSL+TGP+ I +Q+ IGA+ Sbjct: 181 WVPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASEN 240 Query: 306 VDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAG 365 DG+ V C+ ++ +PD+ FTINGV Y + P+AY L C SGFQG+++ +G Sbjct: 241 SDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYIL----QSEGSCISGFQGMNLPTESG 296 Query: 366 PLWILGDVFIRQFYSVFDRGNNRVGLAP 393 LWILGDVFIRQ+++VFDR NN+VGLAP Sbjct: 297 ELWILGDVFIRQYFTVFDRANNQVGLAP 324 >5UX4-A nrPDB Length = 420 Score = 363 bits (931), Expect = e-101, Method: Compositional matrix adjust. Identities = 182/398 (45%), Positives = 249/398 (62%), Gaps = 10/398 (2%) Query: 7 LLLVLLELGEAQGSLHRVPLRRHPSLKKKL-RARSQLSEFWKSHNLDMIQFTESCSMDQS 65 + L L + SL R+PLR+ S+++ + + + + S + Sbjct: 6 VFLFFLSVTTGVHSLIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPRTKEP 65 Query: 66 AKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCT--SPACKTHSRFQPS 123 E L NYLD +Y+G I IG+PPQ FTV+FDTGSSNLWVPS++C AC H ++ Sbjct: 66 VSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSD 125 Query: 124 QSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVE------GLTVVGQQFGESVTEPGQTFV 177 +SSTY + G SF I YG+GSLSG + D VSV G+ V Q FGE+ +PG F+ Sbjct: 126 KSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFI 185 Query: 178 DAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYD 237 A+FDGILG+GYP ++V V PVFDN+M Q LV+ +FS Y++ +P G G EL+ GG D Sbjct: 186 AAKFDGILGMGYPFISVNNVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTD 245 Query: 238 HSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQL 297 ++ G L+++ VT++AYWQ+ +D ++VG + C GC+AIVDTGTSL+ GP D++K+L Sbjct: 246 SRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKEL 305 Query: 298 QNAIGAAP-VDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQ 356 Q AIGA P + GEY + C ++ +P +TF + G Y L P Y L G C SGF Sbjct: 306 QKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFM 365 Query: 357 GLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPA 394 G+DI PP+GPLWILGDVFI +Y+VFDR NRVG A A Sbjct: 366 GMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 403 >4AA9-A nrPDB Length = 320 Score = 356 bits (913), Expect = 1e-98, Method: Compositional matrix adjust. Identities = 182/331 (54%), Positives = 223/331 (67%), Gaps = 12/331 (3%) Query: 66 AKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQS 125 A+EPL +YLD +YFG I IG+PPQ FTV+FDTGSS+LWVPS+YC S CK H RF P +S Sbjct: 1 AREPLTSYLDSQYFGKIYIGTPPQEFTVVFDTGSSDLWVPSIYCKSNVCKNHHRFDPRKS 60 Query: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185 ST+ G+ SI YGTGS+ G +G D V+V + Q G S +PG+ F +EFDGIL Sbjct: 61 STFRNLGKPLSIHYGTGSMEGFLGYDTVTVSNIVDPNQTVGLSTEQPGEVFTYSEFDGIL 120 Query: 186 GLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245 GL YPSLA PVFDNMM ++LV +FSVYM N G GS L G D S+++GSL Sbjct: 121 GLAYPSLASEYSVPVFDNMMDRHLVARDLFSVYMDRN---GQGSMLTLGAIDPSYYTGSL 177 Query: 246 NWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAP 305 +WVPVT Q YWQ +D++ + G + C GCQAI+DTGTS++ GPS I ++Q AIGA Sbjct: 178 HWVPVTLQQYWQFTVDSVTINGVAVACVGGCQAILDTGTSVLFGPSSDILKIQMAIGATE 237 Query: 306 VD-GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPA 364 GE+ V C NL MP V F ING Y LSP+AYT D FC+SGFQG + Sbjct: 238 NRYGEFDVNCGNLRSMPTVVFEINGRDYPLSPSAYTSKD----QGFCTSGFQGDN----N 289 Query: 365 GPLWILGDVFIRQFYSVFDRGNNRVGLAPAV 395 LWILGDVFIR++YSVFDR NNRVGLA A+ Sbjct: 290 SELWILGDVFIREYYSVFDRANNRVGLAKAI 320 >4CMS-A nrPDB Length = 323 Score = 347 bits (889), Expect = 7e-96, Method: Compositional matrix adjust. Identities = 178/331 (53%), Positives = 219/331 (66%), Gaps = 12/331 (3%) Query: 66 AKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQS 125 A PL NYLD +YFG I +G+PPQ FTV+FDTGSS+ WVPS+YC S ACK H RF P +S Sbjct: 4 ASVPLTNYLDSQYFGKIYLGTPPQEFTVLFDTGSSDFWVPSIYCKSNACKNHQRFDPRKS 63 Query: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185 ST+ G+ SI YGTGS+ GI+G D V+V + + Q G S EPG F AEFDGIL Sbjct: 64 STFQNLGKPLSIHYGTGSMQGILGYDTVTVSNIVDIQQTVGLSTQEPGDVFTYAEFDGIL 123 Query: 186 GLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245 G+ YPSLA PVFDNMM ++LV +FSVYM N G S L G D S+++GSL Sbjct: 124 GMAYPSLASEYSIPVFDNMMNRHLVAQDLFSVYMDRN---GQESMLTLGAIDPSYYTGSL 180 Query: 246 NWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAP 305 +WVPVT Q YWQ +D++ + G V+ C GCQAI+DTGTS + GPS I +Q AIGA Sbjct: 181 HWVPVTVQQYWQFTVDSVTISGVVVACEGGCQAILDTGTSKLVGPSSDILNIQQAIGATQ 240 Query: 306 VD-GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPA 364 GE+ ++C NL+ MP V F ING Y L+P+AYT D FC+SGFQ + Sbjct: 241 NQYGEFDIDCDNLSYMPTVVFEINGKMYPLTPSAYTSQD----QGFCTSGFQSEN----H 292 Query: 365 GPLWILGDVFIRQFYSVFDRGNNRVGLAPAV 395 WILGDVFIR++YSVFDR NN VGLA A+ Sbjct: 293 SQKWILGDVFIREYYSVFDRANNLVGLAKAI 323 >1AM5-A nrPDB Length = 324 Score = 336 bits (862), Expect = 9e-93, Method: Compositional matrix adjust. Identities = 167/329 (50%), Positives = 220/329 (66%), Gaps = 9/329 (2%) Query: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSST 127 E + N D EY+G ISIG+PP++F VIFDTGSSNLWV S +C++ AC H++F+P QSST Sbjct: 4 EQMKNEADTEYYGVISIGTPPESFKVIFDTGSSNLWVSSSHCSAQACSNHNKFKPRQSST 63 Query: 128 YSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGL 187 Y + G++ + YGTG + GI+G D VSV G + Q+ GES TEPG A FDGILGL Sbjct: 64 YVETGKTVDLTYGTGGMRGILGQDTVSVGGGSDPNQELGESQTEPGPFQAAAPFDGILGL 123 Query: 188 GYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNW 247 YPS+A G PVFDNM +Q+LV+ +FS Y+S G GSE++ GG D+SH++GS++W Sbjct: 124 AYPSIAAAGAVPVFDNMGSQSLVEKDLFSFYLSGG--GANGSEVMLGGVDNSHYTGSIHW 181 Query: 248 VPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD 307 +PVT + YWQ+ALD I V G C EGCQAIVDTGTS I P + + IGA+ Sbjct: 182 IPVTAEKYWQVALDGITVNGQTAAC-EGCQAIVDTGTSKIVAPVSALANIMKDIGASENQ 240 Query: 308 GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQ-FCSSGFQGLDIHPPAGP 366 GE CA++ +PD+TFTINGV L P+AY ++G Q FC+SG + Sbjct: 241 GEMMGNCASVQSLPDITFTINGVKQPLPPSAY-----IEGDQAFCTSGLGSSGVPSNTSE 295 Query: 367 LWILGDVFIRQFYSVFDRGNNRVGLAPAV 395 LWI GDVF+R +Y+++DR NN+VG APA Sbjct: 296 LWIFGDVFLRNYYTIYDRTNNKVGFAPAA 324 >1AVF-A nrPDB Length = 329 Score = 328 bits (840), Expect = 3e-90, Method: Compositional matrix adjust. Identities = 169/331 (51%), Positives = 227/331 (68%), Gaps = 9/331 (2%) Query: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSST 127 EP+ Y+D YFG ISIG+PPQNF V+FDTGSSNLWVPSVYC S AC +HSRF PS+SST Sbjct: 5 EPMA-YMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQSQACTSHSRFNPSESST 63 Query: 128 YSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGL 187 YS GQ+FS+QYG+GSL+G G D ++V+ + V Q+FG S EPG FV A+FDGI+GL Sbjct: 64 YSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGL 123 Query: 188 GYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNW 247 YP+L+V T M+ + + P+FSVY+ SN +G +G ++FGG D S ++G + W Sbjct: 124 AYPALSVDEATTAMQGMVQEGALTSPVFSVYL-SNQQGSSGGAVVFGGVDSSLYTGQIYW 182 Query: 248 VPVTKQAYWQIALDNIQVGGTVM-FCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPV 306 PVT++ YWQI ++ +GG +CSEGCQAIVDTGTSL+T P + L A GA Sbjct: 183 APVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGAQED 242 Query: 307 D-GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAG 365 + G++ V C ++ +P +TF INGV + L P++Y L + +G +C+ G + + G Sbjct: 243 EYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYILSN--NG--YCTVGVEPTYLSSQNG 298 Query: 366 -PLWILGDVFIRQFYSVFDRGNNRVGLAPAV 395 PLWILGDVF+R +YSV+D GNNRVG A A Sbjct: 299 QPLWILGDVFLRSYYSVYDLGNNRVGFATAA 329 >5N71-A nrPDB Length = 345 Score = 316 bits (809), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 154/332 (46%), Positives = 217/332 (65%), Gaps = 10/332 (3%) Query: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSST 127 EPL+N LD+ Y+G ISIG+PPQ+F VIFDTGS+NLW+PS CT+ C H R+ S+SST Sbjct: 8 EPLVNLLDVVYYGPISIGTPPQDFQVIFDTGSANLWLPSSKCTTKYCLHHHRYDSSKSST 67 Query: 128 YSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGL 187 Y G++F+I YG+G++ G I D + V GQ GE++ G++ ++A FDGILGL Sbjct: 68 YEADGRNFTIVYGSGNVEGFISKDVCRIGSAKVSGQPLGEALVVGGESLLEAPFDGILGL 127 Query: 188 GYPSLAVGGVTPVFDNMMAQNLV-DLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLN 246 YPS+AV GV PVFDNMM Q L+ + +FSVY++ +P G E++FGG DH H+ GS+ Sbjct: 128 AYPSIAVDGVVPVFDNMMKQGLLGEQNVFSVYLNRDPSSKEGGEVLFGGIDHDHYKGSIT 187 Query: 247 WVPVTKQAYWQIALDNIQ-----VGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAI 301 +VPVT + YWQ +D ++ + C +GC+AI +TGTSLITGP +++ L + Sbjct: 188 YVPVTAKGYWQFHVDGVKSVSASKSAPELLCKDGCEAIANTGTSLITGPPEEVDSLNQYL 247 Query: 302 GAAPVD-GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDI 360 G + G+Y ++C L +P+VTFTI+G ++L Y L G C SGF GL++ Sbjct: 248 GGTKTEGGQYLLDCDKLESLPNVTFTISGKEFSLRSKDYVLKVNQQGQTLCVSGFMGLEM 307 Query: 361 HPPAGPLWILGDVFIRQFYSVFDRGNNRVGLA 392 PLWILGDVF+ +Y++FDR +RVG A Sbjct: 308 ---PQPLWILGDVFLGPYYTIFDRDQDRVGFA 336 >5MKT-A nrPDB Length = 389 Score = 304 bits (778), Expect = 5e-83, Method: Compositional matrix adjust. Identities = 158/384 (41%), Positives = 235/384 (61%), Gaps = 17/384 (4%) Query: 19 GSLHRVPLRRHPSLKKKLRAR----SQLSEFWKSHNLDMIQFTESCSM-DQSAKEPLINY 73 + R+PL++ PS+++ L R ++LS W FT+ S+ + ++ L NY Sbjct: 6 ATFERIPLKKMPSVREILEERGVDMTRLSAEWGV-------FTKRPSLTNLTSPVVLTNY 58 Query: 74 LDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSP--ACKTHSRFQPSQSSTYSQP 131 L+ +Y+G I IG+PPQ F VIFDTGS+NLWVPS C+ AC HS ++ S SS+Y + Sbjct: 59 LNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMEN 118 Query: 132 GQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPS 191 G F+I YG+G + G + D V+V G+TV Q FGE P F+ A+FDG+LG+G+P+ Sbjct: 119 GSDFTIHYGSGRVKGFLSQDSVTVGGITVT-QTFGEVTELPLIPFMLAKFDGVLGMGFPA 177 Query: 192 LAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVT 251 AVGGVTPVFD++++Q ++ +FSVY + G E++ GG D H+ G+ ++V ++ Sbjct: 178 QAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHL-LGGEVVLGGSDPQHYQGNFHYVSIS 236 Query: 252 KQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD-GEY 310 K WQI + + VG + + C EGC +VDTG+S I+ P+ +K + A+GA EY Sbjct: 237 KTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEY 296 Query: 311 AVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWIL 370 V C+ + +PD++F + G YTLS T Y L + C+ +DI PP GP+W+L Sbjct: 297 VVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVL 356 Query: 371 GDVFIRQFYSVFDRGNNRVGLAPA 394 G FIR+FY+ FDR NNR+G A A Sbjct: 357 GATFIRKFYTEFDRHNNRIGFALA 380 >5MLG-A nrPDB Length = 389 Score = 297 bits (761), Expect = 5e-81, Method: Compositional matrix adjust. Identities = 153/383 (39%), Positives = 226/383 (59%), Gaps = 15/383 (3%) Query: 19 GSLHRVPLRRHPSLKKKLRAR----SQLSEFWKSHNLDMIQFTESCSMDQSAKEPLINYL 74 S R+ L++ PS+++ L R +++S W +S + ++ L NYL Sbjct: 6 ASFGRILLKKMPSVREILEERGVDMTRISAEWGEF------IKKSSFTNVTSPVVLTNYL 59 Query: 75 DMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQSSTYSQPG 132 D +Y+G I IG+P Q F VIFDTGS+NLWVPS C AC+ H+ + S+SS+Y + G Sbjct: 60 DTQYYGEIGIGTPSQTFKVIFDTGSANLWVPSTKCGPLYTACEIHNLYDSSESSSYMENG 119 Query: 133 QSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSL 192 F+I YG+G + G + D V+V G+ +V Q FGE P F+ A+FDG+LG+G+P+ Sbjct: 120 TEFTIHYGSGKVKGFLSQDVVTVGGI-IVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQ 178 Query: 193 AVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTK 252 AV GV PVFD++++Q ++ +FSVY S G E++ GG D H+ G+ ++V ++K Sbjct: 179 AVDGVIPVFDHILSQRVLKEEVFSVYYSRESHL-LGGEVVLGGSDPQHYQGNFHYVSISK 237 Query: 253 QAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVDGE-YA 311 WQI + + VG + C EGC A+VDTGTS I+GP+ ++ + A+G Y Sbjct: 238 AGSWQITMKGVSVGPATLLCEEGCMAVVDTGTSYISGPTSSLQLIMQALGVKEKRANNYV 297 Query: 312 VECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILG 371 V C+ + +PD++F + G YTLS Y + C QGLDI PP GP+W+LG Sbjct: 298 VNCSQVPTLPDISFYLGGRTYTLSNMDYVQKNPFRNDDLCILALQGLDIPPPTGPVWVLG 357 Query: 372 DVFIRQFYSVFDRGNNRVGLAPA 394 FIR+FY+ FDR NNR+G A A Sbjct: 358 ATFIRKFYTEFDRHNNRIGFALA 380 >1SMR-A nrPDB Length = 335 Score = 294 bits (753), Expect = 4e-80, Method: Compositional matrix adjust. Identities = 146/328 (44%), Positives = 209/328 (63%), Gaps = 5/328 (1%) Query: 70 LINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSP--ACKTHSRFQPSQSST 127 L NYL+ +Y+G I IG+PPQ F VIFDTGS+NLWVPS C+ AC HS ++ S SS+ Sbjct: 9 LTNYLNSQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSS 68 Query: 128 YSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGL 187 Y + G F+I YG+G + G + D V+V G+TV Q FGE P F+ A+FDG+LG+ Sbjct: 69 YMENGDDFTIHYGSGRVKGFLSQDSVTVGGITVT-QTFGEVTQLPLIPFMLAQFDGVLGM 127 Query: 188 GYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNW 247 G+P+ AVGGVTPVFD++++Q ++ +FSVY + P G E++ GG D H+ G ++ Sbjct: 128 GFPAQAVGGVTPVFDHILSQGVLKEKVFSVYYNRGPHL-LGGEVVLGGSDPQHYQGDFHY 186 Query: 248 VPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD 307 V ++K WQI + + VG + + C EGC+ +VDTG+S I+ P+ +K + A+GA Sbjct: 187 VSLSKTDSWQITMKGVSVGSSTLLCEEGCEVVVDTGSSFISAPTSSLKLIMQALGAKEKR 246 Query: 308 -GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGP 366 EY V C+ + +PD++F + G YTLS T Y L + C+ +DI PP GP Sbjct: 247 LHEYVVSCSQVPTLPDISFNLGGRAYTLSSTDYVLQYPNRRDKLCTVALHAMDIPPPTGP 306 Query: 367 LWILGDVFIRQFYSVFDRGNNRVGLAPA 394 +W+LG FIR+FY+ FDR NNR+G A A Sbjct: 307 VWVLGATFIRKFYTEFDRHNNRIGFALA 334 >4AMT-A nrPDB Length = 383 Score = 293 bits (751), Expect = 7e-80, Method: Compositional matrix adjust. Identities = 143/380 (37%), Positives = 223/380 (58%), Gaps = 9/380 (2%) Query: 20 SLHRVPLRRHPSLKKKLRARS-QLSEFWKSHNLDMIQFTESCSMDQSAKEPLINYLDMEY 78 + R+ L+R PS+++ L+ R ++ + M + T + ++ L NY+D +Y Sbjct: 7 TFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLTLG---NTTSSVILTNYMDTQY 63 Query: 79 FGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTS--PACKTHSRFQPSQSSTYSQPGQSFS 136 +G I IG+PPQ F V+FDTGSSN+WVPS C+ AC H F S SS+Y G + Sbjct: 64 YGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELT 123 Query: 137 IQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGG 196 ++Y TG++SG + D ++V G+TV Q FGE P F+ AEFDG++G+G+ A+G Sbjct: 124 LRYSTGTVSGFLSQDIITVGGITVT-QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGR 182 Query: 197 VTPVFDNMMAQNLVDLPMFSVYMSSNPEGGA--GSELIFGGYDHSHFSGSLNWVPVTKQA 254 VTP+FDN+++Q ++ +FS Y + + E G +++ GG D H+ G+ +++ + K Sbjct: 183 VTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTG 242 Query: 255 YWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVDGEYAVEC 314 WQI + + VG + + C +GC A+VDTG S I+G + I++L A+GA +Y V+C Sbjct: 243 VWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLFDYVVKC 302 Query: 315 ANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILGDVF 374 +PD++F + G YTL+ Y + + C+ +DI PP GP W LG F Sbjct: 303 NEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATF 362 Query: 375 IRQFYSVFDRGNNRVGLAPA 394 IR+FY+ FDR NNR+G A A Sbjct: 363 IRKFYTEFDRRNNRIGFALA 382 >5NFG-A nrPDB Length = 383 Score = 287 bits (734), Expect = 6e-78, Method: Compositional matrix adjust. Identities = 162/390 (41%), Positives = 221/390 (56%), Gaps = 20/390 (5%) Query: 17 AQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQ-------FTESCSMDQSAKEP 69 + G L RV L+ K+K+ QL ++H + M+ F + S Sbjct: 3 SNGGLLRVGLK-----KRKVDRLDQL----RAHGVHMLGNARKDFGFRRTLRDSGSGIVA 53 Query: 70 LINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC-TSPACKTHSRFQPSQSSTY 128 L N D Y+G I IG+PPQNF VIFDTGSS+LWVPS C TS AC H R+ SSTY Sbjct: 54 LTNDRDTAYYGEIGIGTPPQNFAVIFDTGSSDLWVPSTKCDTSLACVIHPRYDSGDSSTY 113 Query: 129 SQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLG 188 G + SIQYGTG++ G D V V L V Q F E+ E F+ +EFDGILGLG Sbjct: 114 KGNGTTASIQYGTGAIVGFYSQDSVEVGDLVVEHQDFIETTEEDDTVFLKSEFDGILGLG 173 Query: 189 YPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWV 248 + ++ G PV+ NM+ Q LV+ +FS +++ N + G EL+FGG D +HF G+ +V Sbjct: 174 FQEISAGKAVPVWYNMVNQGLVEEAVFSFWLNRNVDEEEGGELVFGGVDPNHFRGNHTYV 233 Query: 249 PVTKQAYWQIALDNIQVGG-TVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD 307 PVT++ YWQ + ++ +G + FC+ GC AI D+GTS GP+ I Q+ AIGA Sbjct: 234 PVTRKGYWQFEMGDVLIGDKSSGFCAGGCAAIADSGTSFFAGPTAIITQINQAIGAKGGG 293 Query: 308 G--EYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAG 365 G E V+C ++ MP++ FTI + ++P Y C SGF LDI P G Sbjct: 294 GSAESIVDCNGISSMPNIAFTIGSKLFEVTPEQYIYKVGEGEAATCISGFTALDIMSPQG 353 Query: 366 PLWILGDVFIRQFYSVFDRGNNRVGLAPAV 395 P+WILGD+F+ +++VFD G RVG A AV Sbjct: 354 PIWILGDMFMGPYHTVFDYGKLRVGFAEAV 383 >3VCM-A nrPDB Length = 335 Score = 284 bits (727), Expect = 4e-77, Method: Compositional matrix adjust. Identities = 134/327 (40%), Positives = 200/327 (61%), Gaps = 6/327 (1%) Query: 70 LINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTS--PACKTHSRFQPSQSST 127 L NY+D +Y+G I IG+PPQ F V+FDTGSSN+WVPS C+ AC H F S SS+ Sbjct: 12 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 71 Query: 128 YSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGL 187 Y G +++Y TG++SG + D ++V G+TV Q FGE P F+ AEFDG++G+ Sbjct: 72 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITVT-QMFGEVTEMPALPFMLAEFDGVVGM 130 Query: 188 GYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNW 247 G+ A+G VTP+FDN+++Q ++ +FS Y + + GG +++ GG D H+ G+ ++ Sbjct: 131 GFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSLGG---QIVLGGSDPQHYEGNFHY 187 Query: 248 VPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD 307 + + K WQI + + VG + + C +GC A+VDTG S I+G + I++L A+GA Sbjct: 188 INLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRL 247 Query: 308 GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPL 367 +Y V+C +PD++F + G YTL+ Y + + C+ +DI PP GP Sbjct: 248 FDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPT 307 Query: 368 WILGDVFIRQFYSVFDRGNNRVGLAPA 394 W LG FIR+FY+ FDR NNR+G A A Sbjct: 308 WALGATFIRKFYTEFDRRNNRIGFALA 334 >1FMX-A nrPDB Length = 329 Score = 280 bits (716), Expect = 7e-76, Method: Compositional matrix adjust. Identities = 148/329 (44%), Positives = 202/329 (61%), Gaps = 7/329 (2%) Query: 69 PLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTY 128 PL NYL+ +Y+ I++G+PPQNF VI DTGSSNLWVPS C S AC HS++ SS+Y Sbjct: 6 PLTNYLNAQYYTDITLGTPPQNFKVILDTGSSNLWVPSNECGSLACFLHSKYDHEASSSY 65 Query: 129 SQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLG 188 G F+IQYGTGSL G I D +S+ LT+ Q F E+ +EPG TF +FDGILGLG Sbjct: 66 KANGTEFAIQYGTGSLEGYISQDTLSIGDLTIPKQDFAEATSEPGLTFAFGKFDGILGLG 125 Query: 189 YPSLAVGGVTPVFDNMMAQNLVDLPMFSVYM-SSNPEGGAGSELIFGGYDHSHFSGSLNW 247 Y +++V V P F N + Q+L+D F+ Y+ ++ + G E FGG D S F G + W Sbjct: 126 YDTISVDKVVPPFYNAIQQDLLDEKRFAFYLGDTSKDTENGGEATFGGIDESKFKGDITW 185 Query: 248 VPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAP-V 306 +PV ++AYW++ + I +G E A +DTGTSLIT PS + + IGA Sbjct: 186 LPVRRKAYWEVKFEGIGLGDEYAEL-ESHGAAIDTGTSLITLPSGLAEMINAEIGAKKGW 244 Query: 307 DGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGP 366 G+Y ++C + +PD+ F NG +T+ P YTL V G C S +D P GP Sbjct: 245 TGQYTLDCNTRDNLPDLIFNFNGYNFTIGPYDYTLE--VSGS--CISAITPMDFPEPVGP 300 Query: 367 LWILGDVFIRQFYSVFDRGNNRVGLAPAV 395 L I+GD F+R++YS++D GNN VGLA A+ Sbjct: 301 LAIVGDAFLRKYYSIYDLGNNAVGLAKAI 329 >4OC6-B nrPDB Length = 243 Score = 269 bits (687), Expect = 2e-72, Method: Compositional matrix adjust. Identities = 124/239 (51%), Positives = 167/239 (69%), Gaps = 1/239 (0%) Query: 157 GLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFS 216 G+ V Q FGE+ +PG TF+ A+FDGILG+ YP ++V V PVFDN+M Q LVD +FS Sbjct: 2 GVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFS 61 Query: 217 VYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGC 276 Y+S +P+ G EL+ GG D ++ GSL+++ VT++AYWQ+ LD ++V + C EGC Sbjct: 62 FYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKEGC 121 Query: 277 QAIVDTGTSLITGPSDKIKQLQNAIGAAP-VDGEYAVECANLNVMPDVTFTINGVPYTLS 335 +AIVDTGTSL+ GP D++++LQ AIGA P + GEY + C ++ +P +T + G Y LS Sbjct: 122 EAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKLS 181 Query: 336 PTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPA 394 P YTL G C SGF G+DI PP+GPLWILGDVFI ++Y+VFDR NNRVG A A Sbjct: 182 PEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGFAEA 240 >1QDM-A nrPDB Length = 478 Score = 221 bits (563), Expect = 5e-58, Method: Compositional matrix adjust. Identities = 121/250 (48%), Positives = 166/250 (66%), Gaps = 5/250 (2%) Query: 70 LINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCT-SPACKTHSRFQPSQSSTY 128 L NY++ +YFG I +G+PPQ FTVIFDTGSSNLWVPS C S AC HSR++ SSTY Sbjct: 46 LKNYMNAQYFGEIGVGTPPQKFTVIFDTGSSNLWVPSAKCYFSIACYLHSRYKAGASSTY 105 Query: 129 SQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLG 188 + G+ +IQYGTGS++G D V+V L V Q+F E+ EPG TF+ A+FDGILGLG Sbjct: 106 KKNGKPAAIQYGTGSIAGYFSEDSVTVGDLVVKDQEFIEATKEPGITFLVAKFDGILGLG 165 Query: 189 YPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWV 248 + ++VG PV+ M+ Q LV P+FS +++ + + G G E+IFGG D H+ G +V Sbjct: 166 FKEISVGKAVPVWYKMIEQGLVSDPVFSFWLNRHVDEGEGGEIIFGGMDPKHYVGEHTYV 225 Query: 249 PVTKQAYWQIALDNIQVGG-TVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD 307 PVT++ YWQ + ++ VGG + FC+ GC AI D+GTSL+ GP+ I ++ IGAA Sbjct: 226 PVTQKGYWQFDMGDVLVGGKSTGFCAGGCAAIADSGTSLLAGPTAIITEINEKIGAA--- 282 Query: 308 GEYAVECANL 317 G + EC + Sbjct: 283 GVVSQECKTI 292 Score = 92.0 bits (227), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 48/103 (46%), Positives = 62/103 (60%), Gaps = 2/103 (1%) Query: 292 DKIKQLQNAIGAAPVDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFC 351 D + QL N + +P+ GE AV+C +L MPD+ FTI G + L P Y L C Sbjct: 377 DYVNQLCNRL-PSPM-GESAVDCGSLGSMPDIEFTIGGKKFALKPEEYILKVGEGAAAQC 434 Query: 352 SSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPA 394 SGF +DI PP GPLWILGDVF+ +++VFD G R+G A A Sbjct: 435 ISGFTAMDIPPPRGPLWILGDVFMGPYHTVFDYGKLRIGFAKA 477 >1B5F-A nrPDB Length = 239 Score = 209 bits (533), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 112/241 (46%), Positives = 150/241 (62%), Gaps = 6/241 (2%) Query: 65 SAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC-TSPACKTHSRFQPS 123 SA L N D YFG I IG+PPQ FTVIFDTGSS LWVPS C S AC+ HS ++ S Sbjct: 2 SAVVALTNDRDTSYFGEIGIGTPPQKFTVIFDTGSSVLWVPSSKCINSKACRAHSMYESS 61 Query: 124 QSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDG 183 SSTY + G +I YGTGS++G D V++ L V Q F E+ E F+ FDG Sbjct: 62 DSSTYKENGTFGAIIYGTGSITGFFSQDSVTIGDLVVKEQDFIEATDEADNVFLHRLFDG 121 Query: 184 ILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSG 243 ILGL + +++V PV+ NM+ Q LV FS +++ N + G EL+FGG D +HF G Sbjct: 122 ILGLSFQTISV----PVWYNMLNQGLVKERRFSFWLNRNVDEEEGGELVFGGLDPNHFRG 177 Query: 244 SLNWVPVTKQAYWQIALDNIQVGG-TVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIG 302 +VPVT Q YWQ + ++ +G + FC+ GCQA D+GTSL++GP+ + Q+ +AIG Sbjct: 178 DHTYVPVTYQYYWQFGIGDVLIGDKSTGFCAPGCQAFADSGTSLLSGPTAIVTQINHAIG 237 Query: 303 A 303 A Sbjct: 238 A 238 >2BJU-A nrPDB Length = 453 Score = 176 bits (447), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 117/331 (35%), Positives = 175/331 (52%), Gaps = 19/331 (5%) Query: 70 LINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYS 129 L+++ ++ ++G +G Q FT I DTGS+NLWVPSV CT+ C T + S+S TY Sbjct: 132 LVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTTAGCLTKHLYDSSKSRTYE 191 Query: 130 QPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPG--QTFVDAEFDGILGL 187 + G + Y +G++SG D V+V L+ + +F E + G T+ + FDGILGL Sbjct: 192 KDGTKVEMNYVSGTVSGFFSKDLVTVGNLS-LPYKFIEVIDTNGFEPTYTASTFDGILGL 250 Query: 188 GYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNW 247 G+ L++G V P+ + QN ++ +F+ Y+ + + L GG + + G L + Sbjct: 251 GWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGF--LTIGGIEERFYEGPLTY 308 Query: 248 VPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKI-KQLQNA-IGAAP 305 + YWQI LD VG ++ E IVD+GTS IT P+D + K LQN + P Sbjct: 309 EKLNHDLYWQITLD-AHVGNIML---EKANCIVDSGTSAITVPTDFLNKMLQNLDVIKVP 364 Query: 306 VDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVD--GMQFCSSGFQGLDIHPP 363 Y C N + +P FT YTL P Y L ++ G C GLD P Sbjct: 365 FLPFYVTLCNN-SKLPTFEFTSENGKYTLEPEYY--LQHIEDVGPGLCMLNIIGLDF--P 419 Query: 364 AGPLWILGDVFIRQFYSVFDRGNNRVGLAPA 394 P +ILGD F+R++++VFD N+ VG+A A Sbjct: 420 V-PTFILGDPFMRKYFTVFDYDNHSVGIALA 449 >5BWY-A nrPDB Length = 376 Score = 176 bits (446), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 117/331 (35%), Positives = 175/331 (52%), Gaps = 19/331 (5%) Query: 70 LINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYS 129 L+++ ++ ++G +G Q FT I DTGS+NLWVPSV CT+ C T + S+S TY Sbjct: 55 LVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTTAGCLTKHLYDSSKSRTYE 114 Query: 130 QPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPG--QTFVDAEFDGILGL 187 + G + Y +G++SG D V+V L+ + +F E + G T+ + FDGILGL Sbjct: 115 KDGTKVEMNYVSGTVSGFFSKDLVTVGNLS-LPYKFIEVIDTNGFEPTYTASTFDGILGL 173 Query: 188 GYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNW 247 G+ L++G V P+ + QN ++ +F+ Y+ + + L GG + + G L + Sbjct: 174 GWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGF--LTIGGIEERFYEGPLTY 231 Query: 248 VPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKI-KQLQNA-IGAAP 305 + YWQI LD VG ++ E IVD+GTS IT P+D + K LQN + P Sbjct: 232 EKLNHDLYWQITLD-AHVGNIML---EKANCIVDSGTSAITVPTDFLNKMLQNLDVIKVP 287 Query: 306 VDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVD--GMQFCSSGFQGLDIHPP 363 Y C N + +P FT YTL P Y L ++ G C GLD P Sbjct: 288 FLPFYVTLCNN-SKLPTFEFTSENGKYTLEPEYY--LQHIEDVGPGLCMLNIIGLDF--P 342 Query: 364 AGPLWILGDVFIRQFYSVFDRGNNRVGLAPA 394 P +ILGD F+R++++VFD N+ VG+A A Sbjct: 343 V-PTFILGDPFMRKYFTVFDYDNHSVGIALA 372 >1XDH-A nrPDB Length = 331 Score = 175 bits (443), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 116/331 (35%), Positives = 174/331 (52%), Gaps = 19/331 (5%) Query: 70 LINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYS 129 L+++ ++ ++G +G Q FT I DTGS+NLWVPSV CT+ C T + S+S TY Sbjct: 10 LVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTTAGCLTKHLYDSSKSRTYE 69 Query: 130 QPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPG--QTFVDAEFDGILGL 187 + G + Y +G++SG D V+V L+ + +F E + G T+ + FDGILGL Sbjct: 70 KDGTKVEMNYVSGTVSGFFSKDLVTVGNLS-LPYKFIEVIDTNGFEPTYTASTFDGILGL 128 Query: 188 GYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNW 247 G+ L++G V P+ + QN ++ +F+ Y+ + + L GG + + G L + Sbjct: 129 GWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGF--LTIGGIEERFYEGPLTY 186 Query: 248 VPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKI-KQLQNA-IGAAP 305 + YWQI LD VG ++ E IVD+GTS IT P+D + K LQN + P Sbjct: 187 EKLNHDLYWQITLD-AHVGNIML---EKANCIVDSGTSAITVPTDFLNKMLQNLDVIKVP 242 Query: 306 VDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVD--GMQFCSSGFQGLDIHPP 363 Y C N + +P FT YTL P Y L ++ G C GLD P Sbjct: 243 FLPFYVTLCNN-SKLPTFEFTSENGKYTLEPEYY--LQHIEDVGPGLCMLNIIGLDFPVP 299 Query: 364 AGPLWILGDVFIRQFYSVFDRGNNRVGLAPA 394 +ILGD F+R++++VFD N+ VG+A A Sbjct: 300 T---FILGDPFMRKYFTVFDYDNHSVGIALA 327 >1UH8-A nrPDB Length = 325 Score = 174 bits (440), Expect = 7e-44, Method: Compositional matrix adjust. Identities = 119/330 (36%), Positives = 183/330 (55%), Gaps = 19/330 (5%) Query: 69 PLINY-LDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSST 127 P+ +Y D+EY+G ++IG+P + F + FDTGSS+LW+ S CT+ + +++ P+QSST Sbjct: 7 PMTDYGNDIEYYGQVTIGTPGKKFNLDFDTGSSDLWIASTLCTNCGSR-QTKYDPNQSST 65 Query: 128 YSQPGQSFSIQYGTG-SLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILG 186 Y G+++SI YG G S SGI+ D V++ GL + GQ E +F DG+LG Sbjct: 66 YQADGRTWSISYGDGSSASGILAKDNVNLGGLLIKGQTI-ELAKREAASFASGPNDGLLG 124 Query: 187 LGYPSL-AVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245 LG+ ++ V GV DN+++Q L+ P+F VY+ + G G E IFGGYD + F GSL Sbjct: 125 LGFDTITTVRGVKTPMDNLISQGLISRPIFGVYL-GKAKNGGGGEYIFGGYDSTKFKGSL 183 Query: 246 NWVPV-TKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAA 304 VP+ + +W I +D VG + + S I+DTGT+L+ P++ + A GA+ Sbjct: 184 TTVPIDNSRGWWGITVDRATVGTSTVASS--FDGILDTGTTLLILPNNIAASVARAYGAS 241 Query: 305 PV-DGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPP 363 DG Y + C P + F+ING + +SP + +F G G+ D Sbjct: 242 DNGDGTYTISCDTSRFKP-LVFSINGASFQVSPDSLVFEEF-QGQCIAGFGYGNWDFA-- 297 Query: 364 AGPLWILGDVFIRQFYSVFDRGNNRVGLAP 393 I+GD F++ Y VF++G V +AP Sbjct: 298 -----IIGDTFLKNNYVVFNQGVPEVQIAP 322 >2ANL-A nrPDB Length = 327 Score = 165 bits (418), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 108/327 (33%), Positives = 162/327 (49%), Gaps = 21/327 (6%) Query: 75 DMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQS 134 ++ ++G +G Q F +IFDTGS+NLWVPS C S C T + S+S +Y + G Sbjct: 13 NLMFYGEGEVGDNHQKFMLIFDTGSANLWVPSKKCNSIGCSTKHLYDSSKSKSYEKDGTK 72 Query: 135 FSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQ---TFVDAEFDGILGLGYPS 191 I YG+G++ G D V++ G + +F E VT+ + AEFDGILGLG+ Sbjct: 73 VEITYGSGTVRGFFSKDLVTL-GYLSLPYKFIE-VTDTDDLEPLYTAAEFDGILGLGWKD 130 Query: 192 LAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVT 251 L++G + P+ + QN +D +F+ Y+ + + L GG + + G L + + Sbjct: 131 LSIGSIDPIVVELKNQNKIDQALFTFYLPVHDKHSG--YLTIGGIEEKFYEGELTYEKLN 188 Query: 252 KQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGA--APVDGE 309 +WQ+ LD + G T M E IVD+GTS IT P+ I + + P Sbjct: 189 HDLFWQVDLD-VNFGKTSM---EKANVIVDSGTSTITAPTSFINKFFKDLNVIKVPFLPF 244 Query: 310 YAVECANLNVMPDVTFTINGVPYTLSPTAYT--LLDFVDGMQFCSSGFQGLDIHPPAGPL 367 Y C N + MP + F YTL P Y LLD D + C +DI Sbjct: 245 YITTCNNKD-MPTLEFKSANNTYTLEPEYYMEPLLDIDDTL--CMLYILPVDIDKNT--- 298 Query: 368 WILGDVFIRQFYSVFDRGNNRVGLAPA 394 +ILGD F+R++++VFD +G A A Sbjct: 299 FILGDPFMRKYFTVFDYDKESIGFAVA 325 >3QS1-A nrPDB Length = 336 Score = 163 bits (412), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 104/322 (32%), Positives = 160/322 (49%), Gaps = 17/322 (5%) Query: 78 YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137 Y+G IG Q F IFDTGS+NLWVPS C + CKT + + ++S TY + G + Sbjct: 23 YYGEAQIGDNKQKFAFIFDTGSANLWVPSAQCNTIGCKTKNLYDSNKSKTYEKDGTKVEM 82 Query: 138 QYGTGSLSGIIGADQVSVEGLTVVGQQFGESVT---EPGQTFVDAEFDGILGLGYPSLAV 194 Y +G++SG D V++ L+ + + T EP T +FDGI+GLG+ L++ Sbjct: 83 NYVSGTVSGFFSKDIVTIANLSFPYKFIEVTDTNGFEPAYTL--GQFDGIVGLGWKDLSI 140 Query: 195 GGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQA 254 G V PV + QN ++ +F+ Y+ + + L GG + + G L + + Sbjct: 141 GSVDPVVVELKNQNKIEQAVFTFYLPFDDKHKG--YLTIGGIEDRFYEGQLTYEKLNHDL 198 Query: 255 YWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAA--PVDGEYAV 312 YWQ+ LD + G + E AIVD+GTS IT P++ + + + P Y Sbjct: 199 YWQVDLD-LHFGNLTV---EKATAIVDSGTSSITAPTEFLNKFFEGLDVVKIPFLPLYIT 254 Query: 313 ECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILGD 372 C N +P + F YTL P Y F G+ C +D++ +ILGD Sbjct: 255 TCNNPK-LPTLEFRSATNVYTLEPEYYLQQIFDFGISLCMVSIIPVDLNKNT---FILGD 310 Query: 373 VFIRQFYSVFDRGNNRVGLAPA 394 F+R++++VFD N+ VG A A Sbjct: 311 PFMRKYFTVFDYDNHTVGFALA 332 >1MIQ-A nrPDB Length = 375 Score = 159 bits (403), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 103/322 (31%), Positives = 161/322 (50%), Gaps = 17/322 (5%) Query: 78 YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137 ++G +G Q F +IFDTGS+NLWVPS C S C + + S+S +Y + G I Sbjct: 64 FYGEGEVGDNHQKFMLIFDTGSANLWVPSKKCNSSGCSIKNLYDSSKSKSYEKDGTKVDI 123 Query: 138 QYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQ-TFVDAEFDGILGLGYPSLAVGG 196 YG+G++ G D V++ L++ + + T+ + + EFDGILGLG+ L++G Sbjct: 124 TYGSGTVKGFFSKDLVTLGHLSMPYKFIEVTDTDDLEPIYSSVEFDGILGLGWKDLSIGS 183 Query: 197 VTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYW 256 + P+ + QN +D +F+ Y+ + + AG L GG + + G++ + + YW Sbjct: 184 IDPIVVELKNQNKIDNALFTFYLPVH-DVHAGY-LTIGGIEEKFYEGNITYEKLNHDLYW 241 Query: 257 QIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGA--APVDGEYAVEC 314 QI LD + G M E IVD+GT+ IT PS+ + + + P Y C Sbjct: 242 QIDLD-VHFGKQTM---EKANVIVDSGTTTITAPSEFLNKFFANLNVIKVPFLPFYVTTC 297 Query: 315 ANLNVMPDVTFTINGVPYTLSPTAYT--LLDFVDGMQFCSSGFQGLDIHPPAGPLWILGD 372 N MP + F YTL P Y +L+ D + C +DI +ILGD Sbjct: 298 DN-KEMPTLEFKSANNTYTLEPEYYMNPILEVDDTL--CMITMLPVDIDSNT---FILGD 351 Query: 373 VFIRQFYSVFDRGNNRVGLAPA 394 F+R++++VFD VG A A Sbjct: 352 PFMRKYFTVFDYDKESVGFAIA 373 >1QS8-A nrPDB Length = 329 Score = 158 bits (400), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 106/325 (32%), Positives = 162/325 (49%), Gaps = 23/325 (7%) Query: 78 YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137 ++G +G Q F +IFDTGS+NLWVPS C S C + + S+S +Y + G I Sbjct: 18 FYGEGEVGDNHQKFMLIFDTGSANLWVPSKKCNSSGCSIKNLYDSSKSKSYEKDGTKVDI 77 Query: 138 QYGTGSLSGIIGADQVSVEGLTVVGQQFGESVT----EPGQTFVDAEFDGILGLGYPSLA 193 YG+G++ G D V++ L+ + +F E + EP + EFDGILGLG+ L+ Sbjct: 78 TYGSGTVKGFFSKDLVTLGHLS-MPYKFIEVIDTDDLEP--IYSSVEFDGILGLGWKDLS 134 Query: 194 VGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQ 253 +G + P+ + QN +D +F+ Y+ + + AG L GG + + G++ + + Sbjct: 135 IGSIDPIVVELKNQNKIDNALFTFYLPVH-DVHAGY-LTIGGIEEKFYEGNITYEKLNHD 192 Query: 254 AYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGA--APVDGEYA 311 YWQI LD + G M E IVD+GT+ IT PS+ + + + P Y Sbjct: 193 LYWQIDLD-VHFGKQTM---EKANVIVDSGTTTITAPSEFLNKFFANLNVIKVPFLPFYV 248 Query: 312 VECANLNVMPDVTFTINGVPYTLSPTAYT--LLDFVDGMQFCSSGFQGLDIHPPAGPLWI 369 C N MP + F YTL P Y +L+ D + C +DI +I Sbjct: 249 TTCDN-KEMPTLEFKSANNTYTLEPEYYMNPILEVDDTL--CMITMLPVDIDSNT---FI 302 Query: 370 LGDVFIRQFYSVFDRGNNRVGLAPA 394 LGD F+R++++VFD VG A A Sbjct: 303 LGDPFMRKYFTVFDYDKESVGFAIA 327 >5JOD-A nrPDB Length = 375 Score = 157 bits (397), Expect = 7e-39, Method: Compositional matrix adjust. Identities = 111/328 (33%), Positives = 165/328 (50%), Gaps = 23/328 (7%) Query: 75 DMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQS 134 ++ ++G IG+ Q F IFDTGS+NLWVPSV C S C T + S S +Y + G Sbjct: 60 NLMFYGEGQIGTNKQPFMFIFDTGSANLWVPSVNCDSIGCSTKHLYDASASKSYEKDGTK 119 Query: 135 FSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQ---TFVDAEFDGILGLGYPS 191 I YG+G++ G D +S+ L+ + +F E VT+ + +EFDGILGLG+ Sbjct: 120 VEISYGSGTVRGYFSKDVISLGDLS-LPYKFIE-VTDADDLEPIYSGSEFDGILGLGWKD 177 Query: 192 LAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVT 251 L++G + PV + QN +D +F+ Y+ + + L GG + + G L + + Sbjct: 178 LSIGSIDPVVVELKKQNKIDNALFTFYLPVHDKHVG--YLTIGGIESDFYEGPLTYEKLN 235 Query: 252 KQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPS---DKIKQLQNAIGAAPVDG 308 YWQI LD I G VM + A+VD+GTS IT P+ +K + N I P Sbjct: 236 HDLYWQIDLD-IHFGKYVM---QKANAVVDSGTSTITAPTSFLNKFFRDMNVI-KVPFLP 290 Query: 309 EYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQ--FCSSGFQGLDIHPPAGP 366 Y C N + +P + F YTL P Y +D + + C +DI Sbjct: 291 LYVTTCDN-DDLPTLEFHSRNNKYTLEPEFY--MDPLSDIDPALCMLYILPVDIDDNT-- 345 Query: 367 LWILGDVFIRQFYSVFDRGNNRVGLAPA 394 +ILGD F+R++++VFD VG A A Sbjct: 346 -FILGDPFMRKYFTVFDYEKESVGFAVA 372 >5I70-B nrPDB Length = 328 Score = 157 bits (396), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 111/328 (33%), Positives = 165/328 (50%), Gaps = 23/328 (7%) Query: 75 DMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQS 134 ++ ++G IG+ Q F IFDTGS+NLWVPSV C S C T + S S +Y + G Sbjct: 13 NLMFYGEGQIGTNKQPFMFIFDTGSANLWVPSVNCDSIGCSTKHLYDASASKSYEKDGTK 72 Query: 135 FSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQ---TFVDAEFDGILGLGYPS 191 I YG+G++ G D +S+ L+ + +F E VT+ + +EFDGILGLG+ Sbjct: 73 VEISYGSGTVRGYFSKDVISLGDLS-LPYKFIE-VTDADDLEPIYSGSEFDGILGLGWKD 130 Query: 192 LAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVT 251 L++G + PV + QN +D +F+ Y+ + + L GG + + G L + + Sbjct: 131 LSIGSIDPVVVELKKQNKIDNALFTFYLPVHDKHVG--YLTIGGIESDFYEGPLTYEKLN 188 Query: 252 KQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPS---DKIKQLQNAIGAAPVDG 308 YWQI LD I G VM + A+VD+GTS IT P+ +K + N I P Sbjct: 189 HDLYWQIDLD-IHFGKYVM---QKANAVVDSGTSTITAPTSFLNKFFRDMNVI-KVPFLP 243 Query: 309 EYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQ--FCSSGFQGLDIHPPAGP 366 Y C N + +P + F YTL P Y +D + + C +DI Sbjct: 244 LYVTTCDN-DDLPTLEFHSRNNKYTLEPEFY--MDPLSDIDPALCMLYILPVDIDDNT-- 298 Query: 367 LWILGDVFIRQFYSVFDRGNNRVGLAPA 394 +ILGD F+R++++VFD VG A A Sbjct: 299 -FILGDPFMRKYFTVFDYEKESVGFAVA 325 >3QVI-A nrPDB Length = 451 Score = 150 bits (380), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 94/322 (29%), Positives = 158/322 (49%), Gaps = 19/322 (5%) Query: 79 FGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSIQ 138 FG +G Q F +F T SSN+WVPS+ CTS +C++ + + S+S TY + + Sbjct: 140 FGEAKLGDNGQKFNFLFHTASSNVWVPSIKCTSESCESKNHYDSSKSKTYEKDDTPVKLT 199 Query: 139 YGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQT--FVDAEFDGILGLGYPSLAVGG 196 G++SGI D V++ L+ V +F E G + +++ DG+ GLG+ L++G Sbjct: 200 SKAGTISGIFSKDLVTIGKLS-VPYKFIEMTEIVGFEPFYSESDVDGVFGLGWKDLSIGS 258 Query: 197 VTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYW 256 + P + QN ++ ++S+Y+ PE L GG + F G LN+ + W Sbjct: 259 IDPYIVELKTQNKIEQAVYSIYLP--PENKNKGYLTIGGIEERFFDGPLNYEKLNHDLMW 316 Query: 257 QIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQL--QNAIGAAPVDGEYAVEC 314 Q+ LD + G S+ I+D+ TS+IT P++ Q ++ P Y C Sbjct: 317 QVDLD-VHFGNV---SSKKANVILDSATSVITVPTEFFNQFVESASVFKVPFLSLYVTTC 372 Query: 315 ANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPP--AGPLWILGD 372 N +P + + YTL P Y ++ ++ S L+I P ++LGD Sbjct: 373 GNTK-LPTLEYRSPNKVYTLEPKQY-----LEPLENIFSALCMLNIVPIDLEKNTFVLGD 426 Query: 373 VFIRQFYSVFDRGNNRVGLAPA 394 F+R++++V+D N+ VG A A Sbjct: 427 PFMRKYFTVYDYDNHTVGFALA 448 >3FNT-A nrPDB Length = 332 Score = 149 bits (376), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 94/322 (29%), Positives = 158/322 (49%), Gaps = 19/322 (5%) Query: 79 FGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSIQ 138 FG +G Q F +F T SSN+WVPS+ CTS +C++ + + S+S TY + + Sbjct: 21 FGEAKLGDNGQKFNFLFHTASSNVWVPSIKCTSESCESKNHYDSSKSKTYEKDDTPVKLT 80 Query: 139 YGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQT--FVDAEFDGILGLGYPSLAVGG 196 G++SGI D V++ L+ V +F E G + +++ DG+ GLG+ L++G Sbjct: 81 SKAGTISGIFSKDLVTIGKLS-VPYKFIEMTEIVGFEPFYSESDVDGVFGLGWKDLSIGS 139 Query: 197 VTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYW 256 + P + QN ++ ++S+Y+ PE L GG + F G LN+ + W Sbjct: 140 IDPYIVELKTQNKIEQAVYSIYLP--PENKNKGYLTIGGIEERFFDGPLNYEKLNHDLMW 197 Query: 257 QIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQL--QNAIGAAPVDGEYAVEC 314 Q+ LD + G S+ I+D+ TS+IT P++ Q ++ P Y C Sbjct: 198 QVDLD-VHFGNV---SSKKANVILDSATSVITVPTEFFNQFVESASVFKVPFLSLYVTTC 253 Query: 315 ANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPP--AGPLWILGD 372 N +P + + YTL P Y ++ ++ S L+I P ++LGD Sbjct: 254 GNTK-LPTLEYRSPNKVYTLEPKQY-----LEPLENIFSALCMLNIVPIDLEKNTFVLGD 307 Query: 373 VFIRQFYSVFDRGNNRVGLAPA 394 F+R++++V+D N+ VG A A Sbjct: 308 PFMRKYFTVYDYDNHTVGFALA 329 >3OAD-B nrPDB Length = 176 Score = 147 bits (371), Expect = 8e-36, Method: Compositional matrix adjust. Identities = 63/167 (37%), Positives = 97/167 (58%) Query: 228 GSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLI 287 G +++ GG D H+ G+ +++ + K WQI + + VG + + C +GC A+VDTG S I Sbjct: 3 GGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYI 62 Query: 288 TGPSDKIKQLQNAIGAAPVDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDG 347 +G + I++L A+GA +Y V+C +PD++F + G YTL+ Y + Sbjct: 63 SGSTSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSS 122 Query: 348 MQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPA 394 + C+ +DI PP GP W LG FIR+FY+ FDR NNR+G A A Sbjct: 123 KKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALA 169 >3O9L-A nrPDB Length = 166 Score = 145 bits (367), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 70/155 (45%), Positives = 102/155 (65%), Gaps = 3/155 (1%) Query: 70 LINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTS--PACKTHSRFQPSQSST 127 L NY+D +Y+G I IG+PPQ F V+FDTGSSN+WVPS C+ AC H F S SS+ Sbjct: 12 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 71 Query: 128 YSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGL 187 Y G +++Y TG++SG + D ++V G+TV Q FGE P F+ AEFDG++G+ Sbjct: 72 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITVT-QMFGEVTEMPALPFMLAEFDGVVGM 130 Query: 188 GYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSN 222 G+ A+G VTP+FDN+++Q ++ +FS Y + + Sbjct: 131 GFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRD 165 >2ASI-A nrPDB Length = 361 Score = 128 bits (322), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 109/362 (30%), Positives = 165/362 (45%), Gaps = 37/362 (10%) Query: 60 CSMDQSAKEPLINYLDMEYFGT-ISIGSPPQNFTVIFDTGSSNLWVPSVYCT-SPACKTH 117 + D S P D+E + +SIG+P Q+F ++FDTGSS+ WVP CT S C Sbjct: 1 AAADGSVDTPGYYDFDLEEYAIPVSIGTPGQDFLLLFDTGSSDTWVPHKGCTKSEGCVGS 60 Query: 118 SRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTF- 176 F PS SST+ + +I YGTG +G+ D +++ +TV Q G T Sbjct: 61 RFFDPSASSTFKATNYNLNITYGTGGANGLYFEDSIAIGDITVTKQILAYVDNVRGPTAE 120 Query: 177 ----VDAEFDGILGLGYPS----LAVGGVT--PVFDNMMAQNLVDLPMFSVYMSSNPEGG 226 D DG+ G YP A G T V N+ Q L+ P+FSVYM++N G Sbjct: 121 QSPNADIFLDGLFGAAYPDNTAMEAEYGSTYNTVHVNLYKQGLISSPLFSVYMNTNSGTG 180 Query: 227 AGSELIFGGYDHSHFSGSLNWVPVTKQ----AYWQIALDNIQVGGTVMFCSEGCQAI-VD 281 E++FGG +++ G + + V + +W + I V G+ QA +D Sbjct: 181 ---EVVFGGVNNTLLGGDIAYTDVMSRYGGYYFWDAPVTGITVDGSAAVRFSRPQAFTID 237 Query: 282 TGTSLITGPSDKIKQLQNAI--GAAPVDGEYAVECANLN--------VMPDVTFTINGVP 331 TGT+ PS ++ A A + V CA+ VM + + + Sbjct: 238 TGTNFFIMPSSAASKIVKAALPDATETQQGWVVPCASYQNSKSTISIVMQKSGSSSDTIE 297 Query: 332 YTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGL 391 ++ P + LL + C I P G +I+G++F+R F +V+D GNNR+G Sbjct: 298 ISV-PVSKMLLPVDQSNETCM-----FIILPDGGNQYIVGNLFLRFFVNVYDFGNNRIGF 351 Query: 392 AP 393 AP Sbjct: 352 AP 353 >3FV3-A nrPDB Length = 339 Score = 127 bits (318), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 111/336 (33%), Positives = 164/336 (48%), Gaps = 42/336 (12%) Query: 77 EYFGTISIGSPPQNFTVIFDTGSSNLWV--PSVYCTSPA-CKTHSRFQPSQSSTYSQPGQ 133 Y +S+GS Q TVI DTGSS+ WV + C CK+ F PS SS+Y G Sbjct: 13 SYASKVSVGSNKQQQTVIIDTGSSDFWVVDSNAQCGKGVDCKSSGTFTPSSSSSYKNLGA 72 Query: 134 SFSIQYGTGSLS-GIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPS- 191 +F+I+YG GS S G G D V++ G+++ GQQ + + QT VD GILG+GY S Sbjct: 73 AFTIRYGDGSTSQGTWGKDTVTINGVSITGQQ----IADVTQTSVD---QGILGIGYTSN 125 Query: 192 -----LAVGGVTPVFDN----MMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFS 242 + TP +DN + Q + +S+Y++S P G+ +IFGG D++ +S Sbjct: 126 EAVYDTSGRQTTPNYDNVPVTLKKQGKIRTNAYSLYLNS-PSAETGT-IIFGGVDNAKYS 183 Query: 243 GSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIG 302 G L VT I+L ++ + G+ +G A++D+GT+L PSD QL + G Sbjct: 184 GKLVAEQVTSSQALTISLASVNLKGSSFSFGDG--ALLDSGTTLTYFPSDFAAQLADKAG 241 Query: 303 AAPVDGE-----YAVECANLNVMPDVTFTI-NGVPYTLSPTAYTLLDFVDGMQFCSSGFQ 356 A V Y ++C N + F NG T+ T Y + +G C G Q Sbjct: 242 ARLVQVARDQYLYFIDC-NTDTSGTTVFNFGNGAKITVPNTEYV---YQNGDGTCLWGIQ 297 Query: 357 GLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLA 392 D ILGD F+R Y +++ N + +A Sbjct: 298 PSDDT-------ILGDNFLRHAYLLYNLDANTISIA 326 >3LIZ-A nrPDB Length = 334 Score = 122 bits (307), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 97/336 (28%), Positives = 155/336 (46%), Gaps = 33/336 (9%) Query: 73 YLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPAC-----KTHSRFQPSQSST 127 +++ +Y G IG+ QNF +FD+ S N+ V S C AC + + + +P Sbjct: 16 FINTQYAGITKIGN--QNFLTVFDSTSCNVVVASQECVGGACVCPNLQKYEKLKPK---- 69 Query: 128 YSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGL 187 Y G + TGS G D +++ LT QQ E Q D ++G+ Sbjct: 70 YISDGNVQVKFFDTGSAVGRGIEDSLTISQLTT-SQQDIVLADELSQEVCILSADVVVGI 128 Query: 188 GYPSL--AVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245 P A+ G T V +N + +NL+ P+FS++ + +G E+IFGG D + G Sbjct: 129 AAPGCPNALKGKT-VLENFVEENLI-APVFSIHHARFQDGEHFGEIIFGGSDWKYVDGEF 186 Query: 246 NWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAA- 304 +VP+ W+ LD +++G T + G QAI+DT ++I GP + + AIG Sbjct: 187 TYVPLVGDDSWKFRLDGVKIGDTTV-APAGTQAIIDTSKAIIVGPKAYVNPINEAIGCVV 245 Query: 305 ---PVDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIH 361 ++C+ + +PDVTF ING + +S Y + C SGFQ Sbjct: 246 EKTTTRRICKLDCSKIPSLPDVTFVINGRNFNISSQYYIQQN----GNLCYSGFQ----- 296 Query: 362 PPAG--PLWILGDVFIRQFYSVFDRGNNRVGLAPAV 395 P G + +GD F+ +YS F+ N +G +V Sbjct: 297 -PCGHSDHFFIGDFFVDHYYSEFNWENKTMGFGRSV 331 >1MPP-A nrPDB Length = 361 Score = 120 bits (302), Expect = 7e-28, Method: Compositional matrix adjust. Identities = 106/376 (28%), Positives = 166/376 (44%), Gaps = 71/376 (18%) Query: 63 DQSAKEPLINYLDMEYFGT-ISIGSPPQNFTVIFDTGSSNLWVPSVYC-TSPACKTHSRF 120 D S P + D+E + +SIG+P Q+F ++FDTGSS+ WVP C S C F Sbjct: 4 DGSVDTPGLYDFDLEEYAIPVSIGTPGQDFYLLFDTGSSDTWVPHKGCDNSEGCVGKRFF 63 Query: 121 QPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFG--ESVTEP-GQTFV 177 PS SST+ + + +I YGTG +GI D ++V G TV Q ++V+ P + Sbjct: 64 DPSSSSTFKETDYNLNITYGTGGANGIYFRDSITVGGATVKQQTLAYVDNVSGPTAEQSP 123 Query: 178 DAE--FDGILGLGYPSLAV------GGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGS 229 D+E DGI G YP V N+ Q L+ P+FSVYM++N GG Sbjct: 124 DSELFLDGIFGAAYPDNTAMEAEYGDTYNTVHVNLYKQGLISSPVFSVYMNTNDGGGQVV 183 Query: 230 ELIFGGYDHSHFSGSLNWVPVTKQA----YWQIALDNIQVGGTVMFCSEGCQAI-VDTGT 284 +++ G + + V K +W + +++ G+ +G QA +DTGT Sbjct: 184 FGG---VNNTLLGGDIQYTDVLKSRGGYFFWDAPVTGVKIDGSDAVSFDGAQAFTIDTGT 240 Query: 285 SLITGPSDKIKQLQNAIGAAPVDGEYAVECANLNVMPDVT-----FTINGVPYTLSPTAY 339 + PS +++ A +PD T +T+ Y S T + Sbjct: 241 NFFIAPSSFAEKVVKA------------------ALPDATESQQGYTVPCSKYQDSKTTF 282 Query: 340 TLLDFVDGMQFCSSGFQGLDIH----------------------PPAGPLWILGDVFIRQ 377 +L+ +Q S +D+ P G +I+G++F+R Sbjct: 283 SLV-----LQKSGSSSDTIDVSVPISKMLLPVDKSGETCMFIVLPDGGNQFIVGNLFLRF 337 Query: 378 FYSVFDRGNNRVGLAP 393 F +V+D G NR+G AP Sbjct: 338 FVNVYDFGKNRIGFAP 353 >4Y9W-A nrPDB Length = 334 Score = 115 bits (289), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 102/326 (31%), Positives = 151/326 (46%), Gaps = 37/326 (11%) Query: 82 ISIGSPPQNFTVIFDTGSSNLWV--PSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSIQY 139 +S+GS Q V+ DTGSS+ WV S C CK + F P S+++ G SFSI Y Sbjct: 18 VSVGSNKQEQQVVLDTGSSDFWVVDSSASCQKGNCKQYGTFDPHSSTSFKSLGSSFSIGY 77 Query: 140 GTGSLS-GIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVT 198 G S S G G D + + G ++ Q+F + + T V+ GILG+G + Sbjct: 78 GDKSSSIGTWGQDTIYLGGTSITNQRFADVTS----TSVN---QGILGVG--RVETESAN 128 Query: 199 PVFDN----MMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQA 254 P +DN + Q + +S+Y+ N G A +IFGG D++ +SG L P+ Sbjct: 129 PPYDNVPITLKKQGKIKTNAYSLYL--NSPGAATGTIIFGGVDNAKYSGKLIEEPLVSDR 186 Query: 255 YWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGA--APV---DGE 309 Y + L ++ G + G +VD+GT++ P + L N +GA PV + Sbjct: 187 YLAVNLKSLNYNGD--NSNAGFGVVVDSGTTISYLPDSIVDDLANKVGAYLEPVGLGNEL 244 Query: 310 YAVECANLNVMPDVTFTI-NGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIH--PPAGP 366 Y ++C N N +FT NG T+ + + L + C G Q D PP Sbjct: 245 YFIDC-NANPQGSASFTFDNGAKITVPLSEFVLQSTANA---CVWGLQSSDRQNVPP--- 297 Query: 367 LWILGDVFIRQFYSVFDRGNNRVGLA 392 ILGD F+R Y VF+ V LA Sbjct: 298 --ILGDNFLRHAYVVFNLDKETVSLA 321 >3PVK-A nrPDB Length = 342 Score = 115 bits (287), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 104/344 (30%), Positives = 157/344 (45%), Gaps = 54/344 (15%) Query: 76 MEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC---------TSPACKTHSRFQPSQSS 126 + Y I++GS Q VI DTGSS+LWVP V T+ CK + PS SS Sbjct: 12 VTYAADITVGSNNQKLNVIVDTGSSDLWVPDVNVDCQVTYSDQTADFCKQKGTYDPSGSS 71 Query: 127 TYSQPGQSFSIQYGTGSLS-GIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185 F I YG GS S G + D V G+++ Q + T +D GIL Sbjct: 72 ASQDLNTPFKIGYGDGSSSQGTLYKDTVGFGGVSIKNQVLAD----VDSTSIDQ---GIL 124 Query: 186 GLGYPSLAVGGVTPVFDN----MMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHF 241 G+GY + GG +DN + Q ++ +S+Y++S P+ G ++IFGG D++ + Sbjct: 125 GVGYKTNEAGGS---YDNVPVTLKKQGVIAKNAYSLYLNS-PDAATG-QIIFGGVDNAKY 179 Query: 242 SGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAI 301 SGSL +PVT +I+L +++V G + ++ ++D+GT++ D Q+ A Sbjct: 180 SGSLIALPVTSDRELRISLGSVEVSGKTI-NTDNVDVLLDSGTTITYLQQDLADQIIKAF 238 Query: 302 -GAAPVDGE----YAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQ 356 G D Y V+C N+ DV F + P + +F +S Q Sbjct: 239 NGKLTQDSNGNSFYEVDC---NLSGDVVFNFSKNAKISVPAS----------EFAAS-LQ 284 Query: 357 GLDIHP--------PAGPLWILGDVFIRQFYSVFDRGNNRVGLA 392 G D P ILGD F+R Y V+D +N + LA Sbjct: 285 GDDGQPYDKCQLLFDVNDANILGDNFLRSAYIVYDLDDNEISLA 328 >1WKR-A nrPDB Length = 340 Score = 112 bits (281), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 105/351 (29%), Positives = 159/351 (45%), Gaps = 55/351 (15%) Query: 69 PLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTY 128 P N L ++Y + +GSP ++++ DTGSSN W+ A K++ + +ST Sbjct: 6 PATNQL-VDYVVNVGVGSPATTYSLLVDTGSSNTWLG-------ADKSYVK-----TSTS 52 Query: 129 SQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLG 188 S S+ YG+GS SG D V++ LT+ Q G + + G V DGILG+G Sbjct: 53 SATSDKVSVTYGSGSFSGTEYTDTVTLGSLTIPKQSIGVASRDSGFDGV----DGILGVG 108 Query: 189 YPSLAVGGVTP--------VFDNMMAQNLVDLPMFSV-YMSSNPEGGAGSELIFGGYDHS 239 L VG ++P V DN+ +Q + + +V + + E EL FG D S Sbjct: 109 PVDLTVGTLSPHTSTSIPTVTDNLFSQGTIPTNLLAVSFEPTTSESSTNGELTFGATDSS 168 Query: 240 HFSGSLNWVPVTK----QAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIK 295 ++GS+ + P+T AYW I +I+ G + S IVDTGT+L SD Sbjct: 169 KYTGSITYTPITSTSPASAYWGIN-QSIRYGSSTSILSS-TAGIVDTGTTLTLIASDAFA 226 Query: 296 QLQNAIGAAPVD--GEYAVECANLNVMPDVTFTINGVPYTLSPTA----YTLLDFVDGM- 348 + + A GA + G + A + + FTI G + L+ A L + G Sbjct: 227 KYKKATGAVADNNTGLLRLTTAQYANLQSLFFTIGGQTFELTANAQIWPRNLNTAIGGSA 286 Query: 349 --------QFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGL 391 S +GLD +I G F+ +FYSV+D N R+GL Sbjct: 287 SSVYLIVGDLGSDSGEGLD--------FINGLTFLERFYSVYDTTNKRLGL 329 >1J71-A nrPDB Length = 334 Score = 108 bits (270), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 96/330 (29%), Positives = 152/330 (46%), Gaps = 37/330 (11%) Query: 78 YFGTISIGSPPQNFTVIFDTGSSNLWV--PSVYC-------TSPACKTHSRFQPSQSSTY 128 Y I +GS Q TV+ DTGSS+LWV C T+ CK F PS SS+ Sbjct: 14 YAADIVVGSNQQKQTVVIDTGSSDLWVVDTDAECQVTYSGQTNNFCKQEGTFDPSSSSSA 73 Query: 129 SQPGQSFSIQYGT-GSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGL 187 Q FSI+YG S G D V G+++ QQF + T T VD GI+G+ Sbjct: 74 QNLNQDFSIEYGDLTSSQGSFYKDTVGFGGISIKNQQFADVTT----TSVDQ---GIMGI 126 Query: 188 GYPSLAVGGVTPVFDN----MMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSG 243 G+ + G ++DN + Q +++ +S+Y+ N E + ++IFGG D++ ++G Sbjct: 127 GFTADEAG--YNLYDNVPVTLKKQGIINKNAYSLYL--NSEDASTGKIIFGGVDNAKYTG 182 Query: 244 SLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGA 303 +L +PVT ++ L +I GT + S ++D+GT++ + +GA Sbjct: 183 TLTALPVTSSVELRVHLGSINFDGTSV--STNADVVLDSGTTITYFSQSTADKFARIVGA 240 Query: 304 APVDGEYAVECANLNVMPDVTFTIN-GVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHP 362 + ++ D F + GV T+ P + +L D C G D + Sbjct: 241 TWDSRNEIYRLPSCDLSGDAVFNFDQGVKITV-PLSELILKDSDS-SICYFGISRNDAN- 297 Query: 363 PAGPLWILGDVFIRQFYSVFDRGNNRVGLA 392 ILGD F+R+ Y V+D + + LA Sbjct: 298 ------ILGDNFLRRAYIVYDLDDKTISLA 321 >2QZW-A nrPDB Length = 341 Score = 106 bits (265), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 104/345 (30%), Positives = 161/345 (46%), Gaps = 47/345 (13%) Query: 71 INYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVP--SVYCTSPA-------CKTHSRFQ 121 +N + Y I+IGS Q F VI DTGSS+LWVP SV C P CK + Sbjct: 7 LNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYT 66 Query: 122 PSQSSTYSQPGQSFSIQYGTGSLS-GIIGADQVSVEGLTVVGQQFGE-SVTEPGQTFVDA 179 P S+T G F I YG GS S G + D V G ++ Q F + + T Q Sbjct: 67 PKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIPQ----- 121 Query: 180 EFDGILGLGYPSLAVGGVTPVFDN----MMAQNLVDLPMFSVYMSSNPEGGAGSELIFGG 235 GILG+GY + G +DN + Q ++ +S+Y++S P G ++IFGG Sbjct: 122 ---GILGIGYKTNEAAG---DYDNVPVTLKNQGVIAKNAYSLYLNS-PNAATG-QIIFGG 173 Query: 236 YDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIK 295 D + +SGSL VPVT +I L++++ G + + ++D+GT++ D + Sbjct: 174 VDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNI--NGNIDVLLDSGTTITYLQQDVAQ 231 Query: 296 QLQNAIGAA-PVDGE----YAVECANLNVMPDVTFTINGVPYTLSPTAYTL-LDFVDGMQ 349 + +A A DG+ Y +C + D F N ++ + +T L + +G Sbjct: 232 DIIDAFQAELKSDGQGHTFYVTDCQTSGTV-DFNFD-NNAKISVPASEFTAPLSYANGQP 289 Query: 350 F--CSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLA 392 + C D + ILGD F+R Y V+D ++++ LA Sbjct: 290 YPKCQLLLGISDAN-------ILGDNFLRSAYLVYDLDDDKISLA 327 >4OD9-A nrPDB Length = 103 Score = 105 bits (262), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 51/90 (56%), Positives = 64/90 (71%), Gaps = 2/90 (2%) Query: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCT--SPACKTHSRFQPSQS 125 E L NY+D +Y+G I IG+PPQ FTV+FDTGSSNLWVPS++C AC H ++ +S Sbjct: 10 EVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKS 69 Query: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSV 155 STY + G SF I YG+GSLSG + D VSV Sbjct: 70 STYVKNGTSFDIHYGSGSLSGYLSQDTVSV 99 >3TPL-A nrPDB Length = 433 Score = 105 bits (261), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 95/349 (27%), Positives = 159/349 (45%), Gaps = 41/349 (11%) Query: 78 YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137 Y+ +++GSPPQ ++ DTGSSN V + +P H +Q SSTY + + Sbjct: 54 YYVEMTVGSPPQTLNILVDTGSSNFAVGA----APHPFLHRYYQRQLSSTYRDLRKGVYV 109 Query: 138 QYGTGSLSGIIGADQVSV-EGLTVVGQQFGESVTEPGQTFVD-AEFDGILGLGYPSLAV- 194 Y G+ +G +G D VS+ G V + ++TE + F++ + ++GILGL Y +A Sbjct: 110 PYTQGAWAGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARP 169 Query: 195 -GGVTPVFDNMMAQ----NLVDLPMFSVYMSSNPE---GGAGSELIFGGYDHSHFSGSLN 246 + P FD+++ Q NL L + N G +I GG DHS ++GSL Sbjct: 170 DDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLW 229 Query: 247 WVPVTKQAYWQIALDNIQVGGT--VMFCSEGC--QAIVDTGTSLITGPSDKIKQLQNAIG 302 + P+ ++ Y+++ + +++ G M C E ++IVD+GT+ + P + +I Sbjct: 230 YTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIK 289 Query: 303 AAPV-----DGEYAVE--------CANLNVMPDVTFTING------VPYTLSPTAYTLLD 343 AA DG + E N+ P ++ + G T+ P Y L Sbjct: 290 AASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQY--LR 347 Query: 344 FVDGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLA 392 V+ + I + ++G V + FY VFDR R+G A Sbjct: 348 PVEDVATSQDDCYKFAISQSSTGT-VMGAVIMEGFYVVFDRARKRIGFA 395 >2H6T-A nrPDB Length = 340 Score = 105 bits (261), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 106/350 (30%), Positives = 165/350 (47%), Gaps = 45/350 (12%) Query: 64 QSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPA--------CK 115 Q+ LIN + Y I++GS Q TV+ DTGSS+LWVP + A CK Sbjct: 1 QTVPVKLINE-QVSYASDITVGSNKQKLTVVIDTGSSDLWVPDSQVSCQAGQGQDPNFCK 59 Query: 116 THSRFQPSQSSTYSQPGQSFSIQYGTGSLS-GIIGADQVSVEGLTVVGQQFGESVTEPGQ 174 + PS SS+ FSI+YG G+ S G D + G+++ QQF + + Sbjct: 60 NEGTYSPSSSSSSQNLNSPFSIEYGDGTTSQGTWYKDTIGFGGISITKQQFADVTS---- 115 Query: 175 TFVDAEFDGILGLGYPSLAVGGVTPVFDN----MMAQNLVDLPMFSVYMSSNPEGGAGSE 230 T VD GILG+GY + G +DN + Q ++ +S+Y+ N + Sbjct: 116 TSVDQ---GILGIGYKTHEAEG---NYDNVPVTLKNQGIISKNAYSLYL--NSRQATSGQ 167 Query: 231 LIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTS---LI 287 +IFGG D++ +SG+L +PVT +I L+ ++V G + + ++D+GT+ L Sbjct: 168 IIFGGVDNAKYSGTLIALPVTSDNELRIHLNTVKVAGQSI--NADVDVLLDSGTTITYLQ 225 Query: 288 TGPSDKIKQLQNAIGAAPVDGE--YAVECANLNVMPDVTFTINGVPYTLSPTAYTL-LDF 344 G +D++ N +G Y V+C NL+ D F N ++ + +T L Sbjct: 226 QGVADQVISAFNGQETYDANGNLFYLVDC-NLSGSVDFAFDKNA-KISVPASEFTAPLYT 283 Query: 345 VDGMQF--CSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLA 392 DG + C F D + ILGD F+R Y V+D +N + LA Sbjct: 284 EDGQVYDQCQLLFGTSDYN-------ILGDNFLRSAYIVYDLDDNEISLA 326 >2QZX-A nrPDB Length = 342 Score = 99.8 bits (247), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 94/343 (27%), Positives = 154/343 (44%), Gaps = 50/343 (14%) Query: 76 MEYFGTISIGSPPQNFTVIFDTGSSNLWVP--SVYC-------TSPACKTHSRFQPSQSS 126 + Y I++GS Q VI DTGSS+LW+P +V C CK+ + P+ S Sbjct: 12 ITYTADITVGSDNQKLNVIVDTGSSDLWIPDSNVICIPKWRGDKGDFCKSAGSYSPASSR 71 Query: 127 TYSQPGQSFSIQYGTGSLS-GIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185 T F I+YG GS + G + D V + G++V Q F + + GIL Sbjct: 72 TSQNLNTRFDIKYGDGSYAKGKLYKDTVGIGGVSVRDQLFANVWSTSARK-------GIL 124 Query: 186 GLGYPSLAVGGVTPV-FDN----MMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSH 240 G+G+ S G T +DN + Q ++ +S+Y++S E G ++IFGG D + Sbjct: 125 GIGFQS---GEATEFDYDNLPISLRNQGIIGKAAYSLYLNS-AEASTG-QIIFGGIDKAK 179 Query: 241 FSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNA 300 +SGSL +P+T + + L ++ V G + ++D+GT++ ++ + A Sbjct: 180 YSGSLVDLPITSEKKLTVGLRSVNVRGRNV--DANTNVLLDSGTTISYFTRSIVRNILYA 237 Query: 301 IGA-----APVDGEYAVECANLNVMPDVTFTIN---GVPYT--LSPTAYTLLDFVDGMQF 350 IGA + + Y +C + D F N VP + L T YT Sbjct: 238 IGAQMKFDSAGNKVYVADCKTSGTI-DFQFGNNLKISVPVSEFLFQTYYT---------- 286 Query: 351 CSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAP 393 F ++ ILGD F+R Y V++ + ++ +AP Sbjct: 287 SGKPFPKCEVRIRESEDNILGDNFLRSAYVVYNLDDKKISMAP 329 >3ZKX-A nrPDB Length = 386 Score = 99.4 bits (246), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 91/346 (26%), Positives = 153/346 (44%), Gaps = 39/346 (11%) Query: 78 YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137 Y+ + IG+PPQ ++ DTGSSN V +P + F +SSTY G ++ Sbjct: 18 YYLEMLIGTPPQKLQILVDTGSSNFAVAG----TPHSYIDTYFDTERSSTYRSKGFDVTV 73 Query: 138 QYGTGSLSGIIGADQVSV-EGLTVVGQQFGESVTEPGQTFVDA-EFDGILGLGYPSLAV- 194 +Y GS +G +G D V++ +G ++ E F+ +++GILGL Y +LA Sbjct: 74 KYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKP 133 Query: 195 -GGVTPVFDNMMAQ----NLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVP 249 + FD+++ Q N+ + M + G G L+ GG + S + G + + P Sbjct: 134 SSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTP 193 Query: 250 VTKQAYWQIALDNIQVGGTVMF--CSE--GCQAIVDTGTSLITGPSDKIKQLQNAIGAAP 305 + ++ Y+QI + +++GG + C E +AIVD+GT+L+ P + A+ A Sbjct: 194 IKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARAS 253 Query: 306 V-----DGEYA---VECANLNVMPDVTF-----------TINGVPYTLSPTAYTLLDFVD 346 + DG + + C + P F + T+ P Y Sbjct: 254 LIPAFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENSSRSFRITILPQLYIQPMMGA 313 Query: 347 GMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLA 392 G+ + F I P L ++G + FY +FDR RVG A Sbjct: 314 GLNYECYRF---GISPSTNAL-VIGATVMEGFYVIFDRAQKRVGFA 355 >4B1C-A nrPDB Length = 375 Score = 95.5 bits (236), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 91/342 (26%), Positives = 154/342 (45%), Gaps = 41/342 (11%) Query: 78 YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137 Y+ +++GSPPQ ++ DTGSSN V + +P H +Q SSTY + + Sbjct: 20 YYVEMTVGSPPQTLNILVDTGSSNFAVGA----APHPFLHRYYQRQLSSTYRDLRKGVYV 75 Query: 138 QYGTGSLSGIIGADQVSV-EGLTVVGQQFGESVTEPGQTFVD-AEFDGILGLGYPSLAV- 194 Y G G +G D VS+ G V + ++TE + F++ + ++GILGL Y +A Sbjct: 76 PYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARP 135 Query: 195 -GGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQ 253 + P FD+++ Q V +FS+ + G DHS ++GSL + P+ ++ Sbjct: 136 DDSLEPFFDSLVKQTHVP-NLFSLQLCGGGSMIIGGI------DHSLYTGSLWYTPIRRE 188 Query: 254 AYWQIALDNIQVGGT--VMFCSEGC--QAIVDTGTSLITGPSDKIKQLQNAIGAAPV--- 306 Y+++ + +++ G M C E ++IVD+GT+ + P + +I AA Sbjct: 189 WYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEK 248 Query: 307 --DGEYAVE--------CANLNVMPDVTFTING------VPYTLSPTAYTLLDFVDGMQF 350 DG + E N+ P ++ + G T+ P Y L V+ + Sbjct: 249 FPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQY--LRPVEDVAT 306 Query: 351 CSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLA 392 I + ++G V + FY VFDR R+G A Sbjct: 307 SQDDCYKFAISQSSTGT-VMGAVIMEGFYVVFDRARKRIGFA 347 >1PPK-E nrPDB Length = 323 Score = 95.1 bits (235), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 96/327 (29%), Positives = 146/327 (44%), Gaps = 27/327 (8%) Query: 75 DMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQS 134 D EY ++IG N FDTGS++LWV S + HS + PS + G + Sbjct: 14 DEEYITPVTIGGTTLNLN--FDTGSADLWVFSTELPASQQSGHSVYNPSATGK-ELSGYT 70 Query: 135 FSIQYGTGS-LSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLA 193 +SI YG GS SG + D V+V G+T GQ + Q D DG+LGL + S+ Sbjct: 71 WSISYGDGSSASGNVFTDSVTVGGVTAHGQAVQAAQQISAQFQQDTNNDGLLGLAFSSIN 130 Query: 194 V---GGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPV 250 T FD + + + P+F+V + G FG D S ++GSL + V Sbjct: 131 TVQPQSQTTFFDTVKSS--LAQPLFAVALKHQQPG----VYDFGFIDSSKYTGSLTYTGV 184 Query: 251 -TKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD-- 307 Q +W +D+ G +G I DTGT+L+ + Q + + A D Sbjct: 185 DNSQGFWSFNVDSYTAGSQ---SGDGFSGIADTGTTLLLLDDSVVSQYYSQVSGAQQDSN 241 Query: 308 -GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGP 366 G Y +C+ +PD + +I+G T+ + DG S+ G+ + G Sbjct: 242 AGGYVFDCS--TNLPDFSVSISGYTATVPGSLINYGPSGDG----STCLGGIQSNSGIG- 294 Query: 367 LWILGDVFIRQFYSVFDRGNNRVGLAP 393 I GD+F++ Y VFD ++G AP Sbjct: 295 FSIFGDIFLKSQYVVFDSDGPQLGFAP 321 >5HCT-A nrPDB Length = 419 Score = 94.4 bits (233), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 105/332 (31%), Positives = 156/332 (46%), Gaps = 30/332 (9%) Query: 65 SAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQ 124 SA I+ LD Y + IG+P Q + FDTGSS+LWV S T+ + + PS+ Sbjct: 93 SATTTPIDSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVDGQTIYTPSK 152 Query: 125 SSTYS-QPGQSF-SIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFV-DAEF 181 S+T G ++ S SG + D VSV GLTV GQ ES + +F D+ Sbjct: 153 STTAKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTGQAV-ESAKKVSSSFTEDSTI 211 Query: 182 DGILGLGYPSLAVGGVTPV-----FDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGY 236 DG+LGL + +L V+P FDN A +D P+F+ + + G FG Sbjct: 212 DGLLGLAFSTLNT--VSPTQQKTFFDNAKAS--LDSPVFTADLGYHAPG----TYNFGFI 263 Query: 237 DHSHFSGSLNWVPV-TKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIK 295 D + ++GS+ + V TKQ +W+ V G+ F S I DTGT+L+ P+ + Sbjct: 264 DTTAYTGSITYTAVSTKQGFWEWTSTGYAV-GSGTFKSTSIDGIADTGTTLLYLPATVVS 322 Query: 296 ----QLQNAIGAAPVDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFC 351 Q+ A ++ V G Y C+ +P TF + G + P Y +DF Sbjct: 323 AYWAQVSGAKSSSSVGG-YVFPCS--ATLPSFTFGV-GSARIVIPGDY--IDFGPISTGS 376 Query: 352 SSGFQGLDIHPPAGPLWILGDVFIRQFYSVFD 383 SS F G+ G + I GDV ++ + VF+ Sbjct: 377 SSCFGGIQSSAGIG-INIFGDVALKAAFVVFN 407 >3PI0-A nrPDB Length = 330 Score = 93.6 bits (231), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 105/332 (31%), Positives = 156/332 (46%), Gaps = 30/332 (9%) Query: 65 SAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQ 124 SA I+ LD Y + IG+P Q + FDTGSS+LWV S T+ + + PS+ Sbjct: 4 SATTTPIDSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVDGQTIYTPSK 63 Query: 125 SSTYS-QPGQSF-SIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFV-DAEF 181 S+T G ++ S SG + D VSV GLTV GQ ES + +F D+ Sbjct: 64 STTAKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTGQAV-ESAKKVSSSFTEDSTI 122 Query: 182 DGILGLGYPSLAVGGVTPV-----FDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGY 236 DG+LGL + +L V+P FDN A +D P+F+ + + G FG Sbjct: 123 DGLLGLAFSTLNT--VSPTQQKTFFDNAKAS--LDSPVFTADLGYHAPG----TYNFGFI 174 Query: 237 DHSHFSGSLNWVPV-TKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIK 295 D + ++GS+ + V TKQ +W+ V G+ F S I DTGT+L+ P+ + Sbjct: 175 DTTAYTGSITYTAVSTKQGFWEWTSTGYAV-GSGTFKSTSIDGIADTGTTLLYLPATVVS 233 Query: 296 ----QLQNAIGAAPVDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFC 351 Q+ A ++ V G Y C+ +P TF + G + P Y +DF Sbjct: 234 AYWAQVSGAKSSSSVGG-YVFPCS--ATLPSFTFGV-GSARIVIPGDY--IDFGPISTGS 287 Query: 352 SSGFQGLDIHPPAGPLWILGDVFIRQFYSVFD 383 SS F G+ G + I GDV ++ + VF+ Sbjct: 288 SSCFGGIQSSAGIG-INIFGDVALKAAFVVFN 318 >1IBQ-A nrPDB Length = 325 Score = 89.7 bits (221), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 100/327 (30%), Positives = 152/327 (46%), Gaps = 26/327 (7%) Query: 75 DMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQS 134 D EY +++G + FDTGS++LWV S S H + PS S+T G S Sbjct: 13 DEEYLTPVTVG--KSTLHLDFDTGSADLWVFSDELPSSEQTGHDLYTPSSSAT-KLSGYS 69 Query: 135 FSIQYGTG-SLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFV-DAEFDGILGLGYPSL 192 + I YG G S SG + D V+V G+T +Q E+ ++ FV D DG+LGL + S+ Sbjct: 70 WDISYGDGSSASGDVYRDTVTVGGVT-TNKQAVEAASKISSEFVQDTANDGLLGLAFSSI 128 Query: 193 AV---GGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVP 249 T FD + +Q +D P+F+V + + G FG D S ++GS+ + Sbjct: 129 NTVQPKAQTTFFDTVKSQ--LDSPLFAVQLKHDAPG----VYDFGYIDDSKYTGSITYTD 182 Query: 250 V-TKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD- 307 + Q YW + D + G S G AI DTGT+LI + + + A Sbjct: 183 ADSSQGYWGFSTDGYSI-GDGSSSSSGFSAIADTGTTLILLDDEIVSAYYEQVSGAQESY 241 Query: 308 --GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAG 365 G Y C+ +PD T I G + P Y +++ S+ + G+ + G Sbjct: 242 EAGGYVFSCS--TDLPDFTVVI-GDYKAVVPGKY--INYAPVSTGSSTCYGGIQSNSGLG 296 Query: 366 PLWILGDVFIRQFYSVFDRGNNRVGLA 392 L ILGDVF++ Y VF+ ++G A Sbjct: 297 -LSILGDVFLKSQYVVFNSEGPKLGFA 322 >1IZE-A nrPDB Length = 323 Score = 84.0 bits (206), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 95/327 (29%), Positives = 141/327 (43%), Gaps = 29/327 (8%) Query: 75 DMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQS 134 D EY +++G + FDTGS++LWV S S H + P SS G + Sbjct: 14 DEEYITQVTVGD--DTLGLDFDTGSADLWVFSSQTPSSERSGHDYYTPG-SSAQKIDGAT 70 Query: 135 FSIQYGTGS-LSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFV-DAEFDGILGLGYPSL 192 +SI YG GS SG + D+V+V G++ Q ES + F D DG+LGL + S+ Sbjct: 71 WSISYGDGSSASGDVYKDKVTVGGVSYDSQAV-ESAEKVSSEFTQDTANDGLLGLAFSSI 129 Query: 193 AVGGVTP---VFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVP 249 TP FDN+ + + P+F+V + N G FG D S ++GS+ + Sbjct: 130 NTVQPTPQKTFFDNVKSS--LSEPIFAVALKHNAPG----VYDFGYTDSSKYTGSITYTD 183 Query: 250 V-TKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD- 307 V Q +W D + S+ I DTGT+L+ + + A D Sbjct: 184 VDNSQGFWGFTADGYSI--GSDSSSDSITGIADTGTTLLLLDDSIVDAYYEQVNGASYDS 241 Query: 308 --GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAG 365 G Y + +PD + TI T+ + D +G F G+ + G Sbjct: 242 SQGGYVFPSSA--SLPDFSVTIGDYTATVPGEYISFADVGNGQTFG-----GIQSNSGIG 294 Query: 366 PLWILGDVFIRQFYSVFDRGNNRVGLA 392 I GDVF++ Y VFD R+G A Sbjct: 295 -FSIFGDVFLKSQYVVFDASGPRLGFA 320 >1B5F-B nrPDB Length = 87 Score = 73.6 bits (179), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 40/86 (46%), Positives = 51/86 (59%), Gaps = 1/86 (1%) Query: 309 EYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLW 368 E V+C L+ MP+V+FTI G + L+P Y L C SGF +D GPLW Sbjct: 2 ELQVDCNTLSSMPNVSFTIGGKKFGLTPEQYILKVGKGEATQCISGFTAMD-ATLLGPLW 60 Query: 369 ILGDVFIRQFYSVFDRGNNRVGLAPA 394 ILGDVF+R +++VFD GN VG A A Sbjct: 61 ILGDVFMRPYHTVFDYGNLLVGFAEA 86 >3EMY-A nrPDB Length = 329 Score = 70.5 bits (171), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 91/332 (27%), Positives = 140/332 (42%), Gaps = 32/332 (9%) Query: 75 DMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQP-SQSSTYSQPGQ 133 D EY ++SIG+P Q + FDTGSS+LWV S + H+ + P S++ G Sbjct: 14 DSEYITSVSIGTPAQVLPLDFDTGSSDLWVFSSETPKSSATGHAIYTPSKSSTSKKVSGA 73 Query: 134 SF-SIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFV-DAEFDGILGLGYPS 191 S+ S SG + D+V++ G +V Q ES T FV D G++GL + S Sbjct: 74 SWSISYGDGSSSSGDVYTDKVTIGGFSVNTQGV-ESATRVSTEFVQDTVISGLVGLAFDS 132 Query: 192 LAVGGVTP----VFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNW 247 V P + + A +L + P+F+ + G FG D S G + + Sbjct: 133 --GNQVRPHPQKTWFSNAASSLAE-PLFTADLRHGQNG----SYNFGYIDTSVAKGPVAY 185 Query: 248 VPV-TKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPV 306 PV Q +W+ VGG + I DTGT+L+ + + + +A Sbjct: 186 TPVDNSQGFWEFTASGYSVGGGKL-NRNSIDGIADTGTTLLLLDDNVVDAYYANVQSAQY 244 Query: 307 DGE---YAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQ---GLDI 360 D + +C +P +F + T+ L +G C G Q G+ I Sbjct: 245 DNQQEGVVFDCD--EDLPSFSFGVGSSTITIPGDLLNLTPLEEGSSTCFGGLQSSSGIGI 302 Query: 361 HPPAGPLWILGDVFIRQFYSVFDRGNNRVGLA 392 + I GDV ++ VFD GN R+G A Sbjct: 303 N-------IFGDVALKAALVVFDLGNERLGWA 327 >4ZL4-A nrPDB Length = 444 Score = 58.5 bits (140), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 80/300 (26%), Positives = 122/300 (40%), Gaps = 66/300 (22%) Query: 57 TESCSMDQSAKEPLINYLD--MEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPAC 114 TE S D K L +D YF I IG+P Q ++I DTGSS+L P C + Sbjct: 7 TEGHSKDLLYKYKLYGDIDEYAYYFLDIDIGTPEQRISLILDTGSSSLSFPCAGCKNCGV 66 Query: 115 KTHSRFQPSQSSTYS---------------QPGQSFSIQ-YGTGS-LSGIIGADQVSV-- 155 + F + S T S G+ +Q Y GS +SG +D VSV Sbjct: 67 HMENPFNLNNSKTSSILYCENEECPFKLNCVKGKCEYMQSYCEGSQISGFYFSDVVSVVS 126 Query: 156 -EGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLP- 213 V ++ F+ + G+LG+ SL+ P F N++ N L Sbjct: 127 YNNERVTFRKLMGCHMHEESLFLYQQATGVLGM---SLSKPQGIPTFVNLLFDNAPQLKQ 183 Query: 214 MFSVYMSSNPEGGAGSELIFGGYDHSHF-----------------SGSLN---------- 246 +F++ +S N G ELI GGYD ++ S SL+ Sbjct: 184 VFTICISEN-----GGELIAGGYDPAYIVRRGGSKSVSGQGSGPVSESLSESGEDPQVAL 238 Query: 247 -------WVPVTKQAYWQIALDNIQVGGT-VMFCSEGCQAIVDTGTSLITGPSDKIKQLQ 298 W VT++ Y+ I + + + GT +M S+G + +VD+G++ P D +L Sbjct: 239 REAEKVVWENVTRKYYYYIKVRGLDMFGTNMMSSSKGLEMLVDSGSTFTHIPEDLYNKLN 298 >3CTV-A nrPDB Length = 110 Score = 29.6 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 29/50 (58%), Gaps = 1/50 (2%) Query: 139 YGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLG 188 +G L+ GA+Q++ + L + +QFG+ + EP +T + + + +L G Sbjct: 57 FGPFELAKQFGAEQIA-KRLEELAKQFGKKIFEPAKTLKEGKLEELLKAG 105 >2C44-A nrPDB Length = 471 Score = 28.9 bits (63), Expect = 3.6, Method: Compositional matrix adjust. Identities = 29/90 (32%), Positives = 39/90 (43%), Gaps = 5/90 (5%) Query: 224 EGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTG 283 EGGA L G YD +L+W+ + A Q +D ++ G V + G A VD G Sbjct: 311 EGGAMERLAVGLYD----GMNLDWLAY-RIAQVQYLVDGLEEIGVVCQQAGGHAAFVDAG 365 Query: 284 TSLITGPSDKIKQLQNAIGAAPVDGEYAVE 313 L P+D+ A V G AVE Sbjct: 366 KLLPHIPADQFPAQALACELYKVAGIRAVE 395 >2PQ6-A nrPDB Length = 482 Score = 28.5 bits (62), Expect = 5.1, Method: Compositional matrix adjust. Identities = 14/43 (32%), Positives = 23/43 (53%) Query: 252 KQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKI 294 K+++ I ++ +GG+V+F SE I D G P DK+ Sbjct: 324 KKSFLWIIRPDLVIGGSVIFSSEFTNEIADRGLIASWCPQDKV 366 >1IQC-A nrPDB Length = 308 Score = 28.1 bits (61), Expect = 6.8, Method: Compositional matrix adjust. Identities = 10/30 (33%), Positives = 19/30 (63%) Query: 147 IIGADQVSVEGLTVVGQQFGESVTEPGQTF 176 + G+D+V+++ +T QF E++ PG F Sbjct: 127 VFGSDEVTIDRITTAIAQFEETLVTPGSKF 156 >3FHH-A nrPDB Length = 640 Score = 27.7 bits (60), Expect = 9.1, Method: Compositional matrix adjust. Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 8/76 (10%) Query: 136 SIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVG 195 ++ YG+G+L G+I D V + L GQ G V G T D LGLG + Sbjct: 108 ALLYGSGALGGVISYDTVDAKDLLQEGQSSGFRVFGTGGT-----GDHSLGLGASAF--- 159 Query: 196 GVTPVFDNMMAQNLVD 211 G T D ++A + D Sbjct: 160 GRTENLDGIVAWSSRD 175 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5UX4-A nrPDB 494 e-140 1TZS-A nrPDB 486 e-138 4AMT-A nrPDB 453 e-128 5MKT-A nrPDB 448 e-126 2PSG-A nrPDB 447 e-126 5MLG-A nrPDB 445 e-125 5NFG-A nrPDB 433 e-122 1SMR-A nrPDB 410 e-115 3VCM-A nrPDB 409 e-114 1PSO-E nrPDB 407 e-114 4PEP-A nrPDB 407 e-114 1AM5-A nrPDB 404 e-113 5N71-A nrPDB 403 e-113 4AA9-A nrPDB 401 e-112 4CMS-A nrPDB 393 e-110 1FMX-A nrPDB 380 e-106 1AVF-A nrPDB 373 e-104 2BJU-A nrPDB 347 4e-96 1MIQ-A nrPDB 345 2e-95 5BWY-A nrPDB 344 3e-95 3QS1-A nrPDB 343 7e-95 2ANL-A nrPDB 343 8e-95 1QS8-A nrPDB 343 9e-95 1XDH-A nrPDB 341 3e-94 5JOD-A nrPDB 332 2e-91 5I70-B nrPDB 331 3e-91 4OC6-B nrPDB 316 1e-86 1QDM-A nrPDB 312 2e-85 3QVI-A nrPDB 310 7e-85 3FNT-A nrPDB 306 1e-83 1B5F-A nrPDB 293 1e-79 2ASI-A nrPDB 276 2e-74 1UH8-A nrPDB 273 1e-73 3TPL-A nrPDB 268 2e-72 3LIZ-A nrPDB 263 1e-70 2QZW-A nrPDB 259 1e-69 1MPP-A nrPDB 258 4e-69 3ZKX-A nrPDB 256 9e-69 3PVK-A nrPDB 255 3e-68 4B1C-A nrPDB 254 4e-68 4Y9W-A nrPDB 250 8e-67 2H6T-A nrPDB 246 1e-65 2QZX-A nrPDB 245 2e-65 1J71-A nrPDB 244 5e-65 3FV3-A nrPDB 244 6e-65 1PPK-E nrPDB 243 1e-64 1IBQ-A nrPDB 240 8e-64 1IZE-A nrPDB 234 5e-62 5HCT-A nrPDB 231 3e-61 3PI0-A nrPDB 219 1e-57 3EMY-A nrPDB 215 4e-56 3OAD-B nrPDB 213 1e-55 3O9L-A nrPDB 205 4e-53 1WKR-A nrPDB 204 5e-53 4ZL4-A nrPDB 186 2e-47 4OD9-A nrPDB 140 1e-33 1B5F-B nrPDB 107 1e-23 Sequences not found previously or not previously below threshold: 3AUP-A nrPDB 55 5e-08 4PPH-A nrPDB 54 1e-07 1T6G-A nrPDB 47 2e-05 3HD8-A nrPDB 45 8e-05 3OS6-A nrPDB 32 0.40 2BKL-A nrPDB 32 0.69 3Q31-A nrPDB 31 1.0 1LPA-B nrPDB 29 3.8 3NJX-A nrPDB 29 4.1 1IGA-A nrPDB 28 5.0 3TBJ-A nrPDB 28 5.2 1FR5-A nrPDB 28 9.1 >5UX4-A nrPDB Length = 420 Score = 494 bits (1271), Expect = e-140, Method: Composition-based stats. Identities = 182/399 (45%), Positives = 249/399 (62%), Gaps = 10/399 (2%) Query: 7 LLLVLLELGEAQGSLHRVPLRRHPSLKKKL-RARSQLSEFWKSHNLDMIQFTESCSMDQS 65 + L L + SL R+PLR+ S+++ + + + + S + Sbjct: 6 VFLFFLSVTTGVHSLIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPRTKEP 65 Query: 66 AKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCT--SPACKTHSRFQPS 123 E L NYLD +Y+G I IG+PPQ FTV+FDTGSSNLWVPS++C AC H ++ Sbjct: 66 VSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSD 125 Query: 124 QSSTYSQPGQSFSIQYGTGSLSGIIGADQVSV------EGLTVVGQQFGESVTEPGQTFV 177 +SSTY + G SF I YG+GSLSG + D VSV G+ V Q FGE+ +PG F+ Sbjct: 126 KSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFI 185 Query: 178 DAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYD 237 A+FDGILG+GYP ++V V PVFDN+M Q LV+ +FS Y++ +P G G EL+ GG D Sbjct: 186 AAKFDGILGMGYPFISVNNVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTD 245 Query: 238 HSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQL 297 ++ G L+++ VT++AYWQ+ +D ++VG + C GC+AIVDTGTSL+ GP D++K+L Sbjct: 246 SRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKEL 305 Query: 298 QNAIGAAP-VDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQ 356 Q AIGA P + GEY + C ++ +P +TF + G Y L P Y L G C SGF Sbjct: 306 QKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFM 365 Query: 357 GLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPAV 395 G+DI PP+GPLWILGDVFI +Y+VFDR NRVG A A Sbjct: 366 GMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKAA 404 >1TZS-A nrPDB Length = 351 Score = 486 bits (1252), Expect = e-138, Method: Composition-based stats. Identities = 343/343 (100%), Positives = 343/343 (100%) Query: 54 IQFTESCSMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPA 113 IQFTESCSMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPA Sbjct: 1 IQFTESCSMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPA 60 Query: 114 CKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPG 173 CKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPG Sbjct: 61 CKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPG 120 Query: 174 QTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIF 233 QTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIF Sbjct: 121 QTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIF 180 Query: 234 GGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDK 293 GGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDK Sbjct: 181 GGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDK 240 Query: 294 IKQLQNAIGAAPVDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSS 353 IKQLQNAIGAAPVDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSS Sbjct: 241 IKQLQNAIGAAPVDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSS 300 Query: 354 GFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPAVP 396 GFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPAVP Sbjct: 301 GFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPAVP 343 >4AMT-A nrPDB Length = 383 Score = 453 bits (1166), Expect = e-128, Method: Composition-based stats. Identities = 144/386 (37%), Positives = 224/386 (58%), Gaps = 9/386 (2%) Query: 14 LGEAQGSLHRVPLRRHPSLKKKLRARS-QLSEFWKSHNLDMIQFTESCSMDQSAKEPLIN 72 L + R+ L+R PS+++ L+ R ++ + M + T + ++ L N Sbjct: 1 LPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLTLG---NTTSSVILTN 57 Query: 73 YLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTS--PACKTHSRFQPSQSSTYSQ 130 Y+D +Y+G I IG+PPQ F V+FDTGSSN+WVPS C+ AC H F S SS+Y Sbjct: 58 YMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKH 117 Query: 131 PGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYP 190 G +++Y TG++SG + D ++V G+TV Q FGE P F+ AEFDG++G+G+ Sbjct: 118 NGTELTLRYSTGTVSGFLSQDIITVGGITVT-QMFGEVTEMPALPFMLAEFDGVVGMGFI 176 Query: 191 SLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGA--GSELIFGGYDHSHFSGSLNWV 248 A+G VTP+FDN+++Q ++ +FS Y + + E G +++ GG D H+ G+ +++ Sbjct: 177 EQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYI 236 Query: 249 PVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVDG 308 + K WQI + + VG + + C +GC A+VDTG S I+G + I++L A+GA Sbjct: 237 NLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLF 296 Query: 309 EYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLW 368 +Y V+C +PD++F + G YTL+ Y + + C+ +DI PP GP W Sbjct: 297 DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTW 356 Query: 369 ILGDVFIRQFYSVFDRGNNRVGLAPA 394 LG FIR+FY+ FDR NNR+G A A Sbjct: 357 ALGATFIRKFYTEFDRRNNRIGFALA 382 >5MKT-A nrPDB Length = 389 Score = 448 bits (1152), Expect = e-126, Method: Composition-based stats. Identities = 156/386 (40%), Positives = 233/386 (60%), Gaps = 11/386 (2%) Query: 14 LGEAQGSLHRVPLRRHPSLKKKLRARS-QLSEFWKSHNLDMIQFTESCS-MDQSAKEPLI 71 L + R+PL++ PS+++ L R ++ + FT+ S + ++ L Sbjct: 1 LPTRTATFERIPLKKMPSVREILEERGVDMTRLSAEWGV----FTKRPSLTNLTSPVVLT 56 Query: 72 NYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSP--ACKTHSRFQPSQSSTYS 129 NYL+ +Y+G I IG+PPQ F VIFDTGS+NLWVPS C+ AC HS ++ S SS+Y Sbjct: 57 NYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYM 116 Query: 130 QPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGY 189 + G F+I YG+G + G + D V+V G+TV Q FGE P F+ A+FDG+LG+G+ Sbjct: 117 ENGSDFTIHYGSGRVKGFLSQDSVTVGGITVT-QTFGEVTELPLIPFMLAKFDGVLGMGF 175 Query: 190 PSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVP 249 P+ AVGGVTPVFD++++Q ++ +FSVY + G E++ GG D H+ G+ ++V Sbjct: 176 PAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGS-HLLGGEVVLGGSDPQHYQGNFHYVS 234 Query: 250 VTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD-G 308 ++K WQI + + VG + + C EGC +VDTG+S I+ P+ +K + A+GA Sbjct: 235 ISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIE 294 Query: 309 EYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLW 368 EY V C+ + +PD++F + G YTLS T Y L + C+ +DI PP GP+W Sbjct: 295 EYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVW 354 Query: 369 ILGDVFIRQFYSVFDRGNNRVGLAPA 394 +LG FIR+FY+ FDR NNR+G A A Sbjct: 355 VLGATFIRKFYTEFDRHNNRIGFALA 380 >2PSG-A nrPDB Length = 370 Score = 447 bits (1151), Expect = e-126, Method: Composition-based stats. Identities = 204/378 (53%), Positives = 263/378 (69%), Gaps = 11/378 (2%) Query: 21 LHRVPLRRHPSLKKKLRARSQLSEFWKSH--NLDMIQFTESCSMDQSAKEPLINYLDMEY 78 L +VPL R SL++ L +L +F K+H N F E+ ++ EPL NYLD EY Sbjct: 1 LVKVPLVRKKSLRQNLIKDGKLKDFLKTHKHNPASKYFPEAAAL--IGDEPLENYLDTEY 58 Query: 79 FGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSIQ 138 FGTI IG+P Q+FTVIFDTGSSNLWVPSVYC+S AC H++F P SST+ Q SI Sbjct: 59 FGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSLACSDHNQFNPDDSSTFEATSQELSIT 118 Query: 139 YGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVT 198 YGTGS++GI+G D V V G++ Q FG S TEPG A FDGILGL YPS++ G T Sbjct: 119 YGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISASGAT 178 Query: 199 PVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQI 258 PVFDN+ Q LV +FSVY+SSN + +GS ++ GG D S+++GSLNWVPV+ + YWQI Sbjct: 179 PVFDNLWDQGLVSQDLFSVYLSSNDD--SGSVVLLGGIDSSYYTGSLNWVPVSVEGYWQI 236 Query: 259 ALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPV-DGEYAVECANL 317 LD+I + G + CS GCQAIVDTGTSL+TGP+ I +Q+ IGA+ DGE + C+++ Sbjct: 237 TLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASENSDGEMVISCSSI 296 Query: 318 NVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQ 377 + +PD+ FTI+GV Y LSP+AY L D C+SGF+G+D+ +G LWILGDVFIRQ Sbjct: 297 DSLPDIVFTIDGVQYPLSPSAYILQD----DDSCTSGFEGMDVPTSSGELWILGDVFIRQ 352 Query: 378 FYSVFDRGNNRVGLAPAV 395 +Y+VFDR NN+VGLAP Sbjct: 353 YYTVFDRANNKVGLAPVA 370 >5MLG-A nrPDB Length = 389 Score = 445 bits (1145), Expect = e-125, Method: Composition-based stats. Identities = 154/388 (39%), Positives = 225/388 (57%), Gaps = 15/388 (3%) Query: 14 LGEAQGSLHRVPLRRHPSLKKKLRARS----QLSEFWKSHNLDMIQFTESCSMDQSAKEP 69 L S R+ L++ PS+++ L R ++S W +S + ++ Sbjct: 1 LPTDTASFGRILLKKMPSVREILEERGVDMTRISAEWGEF------IKKSSFTNVTSPVV 54 Query: 70 LINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCT--SPACKTHSRFQPSQSST 127 L NYLD +Y+G I IG+P Q F VIFDTGS+NLWVPS C AC+ H+ + S+SS+ Sbjct: 55 LTNYLDTQYYGEIGIGTPSQTFKVIFDTGSANLWVPSTKCGPLYTACEIHNLYDSSESSS 114 Query: 128 YSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGL 187 Y + G F+I YG+G + G + D V+V G+ V Q FGE P F+ A+FDG+LG+ Sbjct: 115 YMENGTEFTIHYGSGKVKGFLSQDVVTVGGIIVT-QTFGEVTELPLIPFMLAKFDGVLGM 173 Query: 188 GYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNW 247 G+P+ AV GV PVFD++++Q ++ +FSVY S G E++ GG D H+ G+ ++ Sbjct: 174 GFPAQAVDGVIPVFDHILSQRVLKEEVFSVYYSRES-HLLGGEVVLGGSDPQHYQGNFHY 232 Query: 248 VPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD 307 V ++K WQI + + VG + C EGC A+VDTGTS I+GP+ ++ + A+G Sbjct: 233 VSISKAGSWQITMKGVSVGPATLLCEEGCMAVVDTGTSYISGPTSSLQLIMQALGVKEKR 292 Query: 308 -GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGP 366 Y V C+ + +PD++F + G YTLS Y + C QGLDI PP GP Sbjct: 293 ANNYVVNCSQVPTLPDISFYLGGRTYTLSNMDYVQKNPFRNDDLCILALQGLDIPPPTGP 352 Query: 367 LWILGDVFIRQFYSVFDRGNNRVGLAPA 394 +W+LG FIR+FY+ FDR NNR+G A A Sbjct: 353 VWVLGATFIRKFYTEFDRHNNRIGFALA 380 >5NFG-A nrPDB Length = 383 Score = 433 bits (1113), Expect = e-122, Method: Composition-based stats. Identities = 161/390 (41%), Positives = 221/390 (56%), Gaps = 20/390 (5%) Query: 17 AQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQ-------FTESCSMDQSAKEP 69 + G L RV L++ +K+ QL ++H + M+ F + S Sbjct: 3 SNGGLLRVGLKK-----RKVDRLDQL----RAHGVHMLGNARKDFGFRRTLRDSGSGIVA 53 Query: 70 LINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC-TSPACKTHSRFQPSQSSTY 128 L N D Y+G I IG+PPQNF VIFDTGSS+LWVPS C TS AC H R+ SSTY Sbjct: 54 LTNDRDTAYYGEIGIGTPPQNFAVIFDTGSSDLWVPSTKCDTSLACVIHPRYDSGDSSTY 113 Query: 129 SQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLG 188 G + SIQYGTG++ G D V V L V Q F E+ E F+ +EFDGILGLG Sbjct: 114 KGNGTTASIQYGTGAIVGFYSQDSVEVGDLVVEHQDFIETTEEDDTVFLKSEFDGILGLG 173 Query: 189 YPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWV 248 + ++ G PV+ NM+ Q LV+ +FS +++ N + G EL+FGG D +HF G+ +V Sbjct: 174 FQEISAGKAVPVWYNMVNQGLVEEAVFSFWLNRNVDEEEGGELVFGGVDPNHFRGNHTYV 233 Query: 249 PVTKQAYWQIALDNIQVGG-TVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD 307 PVT++ YWQ + ++ +G + FC+ GC AI D+GTS GP+ I Q+ AIGA Sbjct: 234 PVTRKGYWQFEMGDVLIGDKSSGFCAGGCAAIADSGTSFFAGPTAIITQINQAIGAKGGG 293 Query: 308 G--EYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAG 365 G E V+C ++ MP++ FTI + ++P Y C SGF LDI P G Sbjct: 294 GSAESIVDCNGISSMPNIAFTIGSKLFEVTPEQYIYKVGEGEAATCISGFTALDIMSPQG 353 Query: 366 PLWILGDVFIRQFYSVFDRGNNRVGLAPAV 395 P+WILGD+F+ +++VFD G RVG A AV Sbjct: 354 PIWILGDMFMGPYHTVFDYGKLRVGFAEAV 383 >1SMR-A nrPDB Length = 335 Score = 410 bits (1055), Expect = e-115, Method: Composition-based stats. Identities = 147/336 (43%), Positives = 211/336 (62%), Gaps = 5/336 (1%) Query: 62 MDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSP--ACKTHSR 119 D + L NYL+ +Y+G I IG+PPQ F VIFDTGS+NLWVPS C+ AC HS Sbjct: 1 TDLISPVVLTNYLNSQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSL 60 Query: 120 FQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDA 179 ++ S SS+Y + G F+I YG+G + G + D V+V G+TV Q FGE P F+ A Sbjct: 61 YESSDSSSYMENGDDFTIHYGSGRVKGFLSQDSVTVGGITVT-QTFGEVTQLPLIPFMLA 119 Query: 180 EFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHS 239 +FDG+LG+G+P+ AVGGVTPVFD++++Q ++ +FSVY + P G E++ GG D Sbjct: 120 QFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEKVFSVYYNRGP-HLLGGEVVLGGSDPQ 178 Query: 240 HFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQN 299 H+ G ++V ++K WQI + + VG + + C EGC+ +VDTG+S I+ P+ +K + Sbjct: 179 HYQGDFHYVSLSKTDSWQITMKGVSVGSSTLLCEEGCEVVVDTGSSFISAPTSSLKLIMQ 238 Query: 300 AIGAAPVD-GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGL 358 A+GA EY V C+ + +PD++F + G YTLS T Y L + C+ + Sbjct: 239 ALGAKEKRLHEYVVSCSQVPTLPDISFNLGGRAYTLSSTDYVLQYPNRRDKLCTVALHAM 298 Query: 359 DIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPA 394 DI PP GP+W+LG FIR+FY+ FDR NNR+G A A Sbjct: 299 DIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALA 334 >3VCM-A nrPDB Length = 335 Score = 409 bits (1051), Expect = e-114, Method: Composition-based stats. Identities = 133/334 (39%), Positives = 202/334 (60%), Gaps = 6/334 (1%) Query: 63 DQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTS--PACKTHSRF 120 + ++ L NY+D +Y+G I IG+PPQ F V+FDTGSSN+WVPS C+ AC H F Sbjct: 5 NTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLF 64 Query: 121 QPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAE 180 S SS+Y G +++Y TG++SG + D ++V G+TV Q FGE P F+ AE Sbjct: 65 DASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVT-QMFGEVTEMPALPFMLAE 123 Query: 181 FDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSH 240 FDG++G+G+ A+G VTP+FDN+++Q ++ +FS Y + + G +++ GG D H Sbjct: 124 FDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDS---LGGQIVLGGSDPQH 180 Query: 241 FSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNA 300 + G+ +++ + K WQI + + VG + + C +GC A+VDTG S I+G + I++L A Sbjct: 181 YEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEA 240 Query: 301 IGAAPVDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDI 360 +GA +Y V+C +PD++F + G YTL+ Y + + C+ +DI Sbjct: 241 LGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDI 300 Query: 361 HPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPA 394 PP GP W LG FIR+FY+ FDR NNR+G A A Sbjct: 301 PPPTGPTWALGATFIRKFYTEFDRRNNRIGFALA 334 >1PSO-E nrPDB Length = 326 Score = 407 bits (1047), Expect = e-114, Method: Composition-based stats. Identities = 186/330 (56%), Positives = 240/330 (72%), Gaps = 7/330 (2%) Query: 67 KEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSS 126 ++PL NYLDMEYFGTI IG+P Q+FTV+FDTGSSNLWVPSVYC+S AC H+RF P SS Sbjct: 3 EQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNPEDSS 62 Query: 127 TYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILG 186 TY ++ SI YGTGS++GI+G D V V G++ Q FG S TEPG A FDGILG Sbjct: 63 TYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILG 122 Query: 187 LGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLN 246 L YPS++ G TPVFDN+ Q LV +FSVY+S++ + +GS +IFGG D S+++GSLN Sbjct: 123 LAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQ--SGSVVIFGGIDSSYYTGSLN 180 Query: 247 WVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPV 306 WVPVT + YWQI +D+I + G + C+EGCQAIVDTGTSL+TGP+ I +Q+ IGA+ Sbjct: 181 WVPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASEN 240 Query: 307 -DGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAG 365 DG+ V C+ ++ +PD+ FTINGV Y + P+AY L C SGFQG+++ +G Sbjct: 241 SDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQ----SEGSCISGFQGMNLPTESG 296 Query: 366 PLWILGDVFIRQFYSVFDRGNNRVGLAPAV 395 LWILGDVFIRQ+++VFDR NN+VGLAP Sbjct: 297 ELWILGDVFIRQYFTVFDRANNQVGLAPVA 326 >4PEP-A nrPDB Length = 326 Score = 407 bits (1046), Expect = e-114, Method: Composition-based stats. Identities = 189/331 (57%), Positives = 239/331 (72%), Gaps = 7/331 (2%) Query: 66 AKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQS 125 EPL NYLD EYFGTI IG+P Q+FTVIFDTGSSNLWVPSVYC+S AC H++F P S Sbjct: 2 GDEPLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSLACSDHNQFNPDDS 61 Query: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185 ST+ Q SI YGTGS++GI+G D V V G++ Q FG S TEPG A FDGIL Sbjct: 62 STFEATSQELSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGIL 121 Query: 186 GLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245 GL YPS++ G TPVFDN+ Q LV +FSVY+SSN + +GS ++ GG D S+++GSL Sbjct: 122 GLAYPSISASGATPVFDNLWDQGLVSQDLFSVYLSSNDD--SGSVVLLGGIDSSYYTGSL 179 Query: 246 NWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAP 305 NWVPV+ + YWQI LD+I + G + CS GCQAIVDTGTSL+TGP+ I +Q+ IGA+ Sbjct: 180 NWVPVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASE 239 Query: 306 V-DGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPA 364 DGE + C++++ +PD+ FTI+GV Y LSP+AY L D C+SGF+G+D+ + Sbjct: 240 NSDGEMVISCSSIDSLPDIVFTIDGVQYPLSPSAYILQD----DDSCTSGFEGMDVPTSS 295 Query: 365 GPLWILGDVFIRQFYSVFDRGNNRVGLAPAV 395 G LWILGDVFIRQ+Y+VFDR NN+VGLAP Sbjct: 296 GELWILGDVFIRQYYTVFDRANNKVGLAPVA 326 >1AM5-A nrPDB Length = 324 Score = 404 bits (1037), Expect = e-113, Method: Composition-based stats. Identities = 165/330 (50%), Positives = 216/330 (65%), Gaps = 7/330 (2%) Query: 66 AKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQS 125 E + N D EY+G ISIG+PP++F VIFDTGSSNLWV S +C++ AC H++F+P QS Sbjct: 2 VTEQMKNEADTEYYGVISIGTPPESFKVIFDTGSSNLWVSSSHCSAQACSNHNKFKPRQS 61 Query: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185 STY + G++ + YGTG + GI+G D VSV G + Q+ GES TEPG A FDGIL Sbjct: 62 STYVETGKTVDLTYGTGGMRGILGQDTVSVGGGSDPNQELGESQTEPGPFQAAAPFDGIL 121 Query: 186 GLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245 GL YPS+A G PVFDNM +Q+LV+ +FS Y+S G GSE++ GG D+SH++GS+ Sbjct: 122 GLAYPSIAAAGAVPVFDNMGSQSLVEKDLFSFYLSGG--GANGSEVMLGGVDNSHYTGSI 179 Query: 246 NWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAP 305 +W+PVT + YWQ+ALD I V G C EGCQAIVDTGTS I P + + IGA+ Sbjct: 180 HWIPVTAEKYWQVALDGITVNGQTAAC-EGCQAIVDTGTSKIVAPVSALANIMKDIGASE 238 Query: 306 VDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAG 365 GE CA++ +PD+TFTINGV L P+AY FC+SG + Sbjct: 239 NQGEMMGNCASVQSLPDITFTINGVKQPLPPSAYI----EGDQAFCTSGLGSSGVPSNTS 294 Query: 366 PLWILGDVFIRQFYSVFDRGNNRVGLAPAV 395 LWI GDVF+R +Y+++DR NN+VG APA Sbjct: 295 ELWIFGDVFLRNYYTIYDRTNNKVGFAPAA 324 >5N71-A nrPDB Length = 345 Score = 403 bits (1035), Expect = e-113, Method: Composition-based stats. Identities = 154/340 (45%), Positives = 218/340 (64%), Gaps = 10/340 (2%) Query: 63 DQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQP 122 + EPL+N LD+ Y+G ISIG+PPQ+F VIFDTGS+NLW+PS CT+ C H R+ Sbjct: 3 EGPYPEPLVNLLDVVYYGPISIGTPPQDFQVIFDTGSANLWLPSSKCTTKYCLHHHRYDS 62 Query: 123 SQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFD 182 S+SSTY G++F+I YG+G++ G I D + V GQ GE++ G++ ++A FD Sbjct: 63 SKSSTYEADGRNFTIVYGSGNVEGFISKDVCRIGSAKVSGQPLGEALVVGGESLLEAPFD 122 Query: 183 GILGLGYPSLAVGGVTPVFDNMMAQNLV-DLPMFSVYMSSNPEGGAGSELIFGGYDHSHF 241 GILGL YPS+AV GV PVFDNMM Q L+ + +FSVY++ +P G E++FGG DH H+ Sbjct: 123 GILGLAYPSIAVDGVVPVFDNMMKQGLLGEQNVFSVYLNRDPSSKEGGEVLFGGIDHDHY 182 Query: 242 SGSLNWVPVTKQAYWQIALDNIQVGGTV-----MFCSEGCQAIVDTGTSLITGPSDKIKQ 296 GS+ +VPVT + YWQ +D ++ + C +GC+AI +TGTSLITGP +++ Sbjct: 183 KGSITYVPVTAKGYWQFHVDGVKSVSASKSAPELLCKDGCEAIANTGTSLITGPPEEVDS 242 Query: 297 LQNAIGAAPVD-GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGF 355 L +G + G+Y ++C L +P+VTFTI+G ++L Y L G C SGF Sbjct: 243 LNQYLGGTKTEGGQYLLDCDKLESLPNVTFTISGKEFSLRSKDYVLKVNQQGQTLCVSGF 302 Query: 356 QGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPAV 395 GL++ PLWILGDVF+ +Y++FDR +RVG A Sbjct: 303 MGLEMPQ---PLWILGDVFLGPYYTIFDRDQDRVGFAEVA 339 >4AA9-A nrPDB Length = 320 Score = 401 bits (1031), Expect = e-112, Method: Composition-based stats. Identities = 182/331 (54%), Positives = 223/331 (67%), Gaps = 12/331 (3%) Query: 66 AKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQS 125 A+EPL +YLD +YFG I IG+PPQ FTV+FDTGSS+LWVPS+YC S CK H RF P +S Sbjct: 1 AREPLTSYLDSQYFGKIYIGTPPQEFTVVFDTGSSDLWVPSIYCKSNVCKNHHRFDPRKS 60 Query: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185 ST+ G+ SI YGTGS+ G +G D V+V + Q G S +PG+ F +EFDGIL Sbjct: 61 STFRNLGKPLSIHYGTGSMEGFLGYDTVTVSNIVDPNQTVGLSTEQPGEVFTYSEFDGIL 120 Query: 186 GLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245 GL YPSLA PVFDNMM ++LV +FSVYM N G GS L G D S+++GSL Sbjct: 121 GLAYPSLASEYSVPVFDNMMDRHLVARDLFSVYMDRN---GQGSMLTLGAIDPSYYTGSL 177 Query: 246 NWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAP 305 +WVPVT Q YWQ +D++ + G + C GCQAI+DTGTS++ GPS I ++Q AIGA Sbjct: 178 HWVPVTLQQYWQFTVDSVTINGVAVACVGGCQAILDTGTSVLFGPSSDILKIQMAIGATE 237 Query: 306 VD-GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPA 364 GE+ V C NL MP V F ING Y LSP+AYT D FC+SGFQG + Sbjct: 238 NRYGEFDVNCGNLRSMPTVVFEINGRDYPLSPSAYTSKD----QGFCTSGFQGDN----N 289 Query: 365 GPLWILGDVFIRQFYSVFDRGNNRVGLAPAV 395 LWILGDVFIR++YSVFDR NNRVGLA A+ Sbjct: 290 SELWILGDVFIREYYSVFDRANNRVGLAKAI 320 >4CMS-A nrPDB Length = 323 Score = 393 bits (1011), Expect = e-110, Method: Composition-based stats. Identities = 178/331 (53%), Positives = 218/331 (65%), Gaps = 12/331 (3%) Query: 66 AKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQS 125 A PL NYLD +YFG I +G+PPQ FTV+FDTGSS+ WVPS+YC S ACK H RF P +S Sbjct: 4 ASVPLTNYLDSQYFGKIYLGTPPQEFTVLFDTGSSDFWVPSIYCKSNACKNHQRFDPRKS 63 Query: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185 ST+ G+ SI YGTGS+ GI+G D V+V + + Q G S EPG F AEFDGIL Sbjct: 64 STFQNLGKPLSIHYGTGSMQGILGYDTVTVSNIVDIQQTVGLSTQEPGDVFTYAEFDGIL 123 Query: 186 GLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245 G+ YPSLA PVFDNMM ++LV +FSVYM N G S L G D S+++GSL Sbjct: 124 GMAYPSLASEYSIPVFDNMMNRHLVAQDLFSVYMDRN---GQESMLTLGAIDPSYYTGSL 180 Query: 246 NWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAP 305 +WVPVT Q YWQ +D++ + G V+ C GCQAI+DTGTS + GPS I +Q AIGA Sbjct: 181 HWVPVTVQQYWQFTVDSVTISGVVVACEGGCQAILDTGTSKLVGPSSDILNIQQAIGATQ 240 Query: 306 VD-GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPA 364 GE+ ++C NL+ MP V F ING Y L+P+AYT D FC+SGFQ Sbjct: 241 NQYGEFDIDCDNLSYMPTVVFEINGKMYPLTPSAYTSQD----QGFCTSGFQ----SENH 292 Query: 365 GPLWILGDVFIRQFYSVFDRGNNRVGLAPAV 395 WILGDVFIR++YSVFDR NN VGLA A+ Sbjct: 293 SQKWILGDVFIREYYSVFDRANNLVGLAKAI 323 >1FMX-A nrPDB Length = 329 Score = 380 bits (975), Expect = e-106, Method: Composition-based stats. Identities = 146/331 (44%), Positives = 200/331 (60%), Gaps = 7/331 (2%) Query: 67 KEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSS 126 PL NYL+ +Y+ I++G+PPQNF VI DTGSSNLWVPS C S AC HS++ SS Sbjct: 4 DVPLTNYLNAQYYTDITLGTPPQNFKVILDTGSSNLWVPSNECGSLACFLHSKYDHEASS 63 Query: 127 TYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILG 186 +Y G F+IQYGTGSL G I D +S+ LT+ Q F E+ +EPG TF +FDGILG Sbjct: 64 SYKANGTEFAIQYGTGSLEGYISQDTLSIGDLTIPKQDFAEATSEPGLTFAFGKFDGILG 123 Query: 187 LGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYM-SSNPEGGAGSELIFGGYDHSHFSGSL 245 LGY +++V V P F N + Q+L+D F+ Y+ ++ + G E FGG D S F G + Sbjct: 124 LGYDTISVDKVVPPFYNAIQQDLLDEKRFAFYLGDTSKDTENGGEATFGGIDESKFKGDI 183 Query: 246 NWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAP 305 W+PV ++AYW++ + I +G E A +DTGTSLIT PS + + IGA Sbjct: 184 TWLPVRRKAYWEVKFEGIGLGDEYAEL-ESHGAAIDTGTSLITLPSGLAEMINAEIGAKK 242 Query: 306 -VDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPA 364 G+Y ++C + +PD+ F NG +T+ P YTL C S +D P Sbjct: 243 GWTGQYTLDCNTRDNLPDLIFNFNGYNFTIGPYDYTLEVSGS----CISAITPMDFPEPV 298 Query: 365 GPLWILGDVFIRQFYSVFDRGNNRVGLAPAV 395 GPL I+GD F+R++YS++D GNN VGLA A+ Sbjct: 299 GPLAIVGDAFLRKYYSIYDLGNNAVGLAKAI 329 >1AVF-A nrPDB Length = 329 Score = 373 bits (959), Expect = e-104, Method: Composition-based stats. Identities = 167/334 (50%), Positives = 224/334 (67%), Gaps = 8/334 (2%) Query: 65 SAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQ 124 S + Y+D YFG ISIG+PPQNF V+FDTGSSNLWVPSVYC S AC +HSRF PS+ Sbjct: 1 SVTYEPMAYMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQSQACTSHSRFNPSE 60 Query: 125 SSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGI 184 SSTYS GQ+FS+QYG+GSL+G G D ++V+ + V Q+FG S EPG FV A+FDGI Sbjct: 61 SSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGI 120 Query: 185 LGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGS 244 +GL YP+L+V T M+ + + P+FSVY+S N +G +G ++FGG D S ++G Sbjct: 121 MGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLS-NQQGSSGGAVVFGGVDSSLYTGQ 179 Query: 245 LNWVPVTKQAYWQIALDNIQVGGT-VMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGA 303 + W PVT++ YWQI ++ +GG +CSEGCQAIVDTGTSL+T P + L A GA Sbjct: 180 IYWAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGA 239 Query: 304 APVD-GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHP 362 + G++ V C ++ +P +TF INGV + L P++Y L + +C+ G + + Sbjct: 240 QEDEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYILSN----NGYCTVGVEPTYLSS 295 Query: 363 PAG-PLWILGDVFIRQFYSVFDRGNNRVGLAPAV 395 G PLWILGDVF+R +YSV+D GNNRVG A A Sbjct: 296 QNGQPLWILGDVFLRSYYSVYDLGNNRVGFATAA 329 >2BJU-A nrPDB Length = 453 Score = 347 bits (891), Expect = 4e-96, Method: Composition-based stats. Identities = 111/329 (33%), Positives = 169/329 (51%), Gaps = 15/329 (4%) Query: 70 LINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYS 129 L+++ ++ ++G +G Q FT I DTGS+NLWVPSV CT+ C T + S+S TY Sbjct: 132 LVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTTAGCLTKHLYDSSKSRTYE 191 Query: 130 QPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPG--QTFVDAEFDGILGL 187 + G + Y +G++SG D V+V L++ +F E + G T+ + FDGILGL Sbjct: 192 KDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLP-YKFIEVIDTNGFEPTYTASTFDGILGL 250 Query: 188 GYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNW 247 G+ L++G V P+ + QN ++ +F+ Y+ + + L GG + + G L + Sbjct: 251 GWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHT--GFLTIGGIEERFYEGPLTY 308 Query: 248 VPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIG--AAP 305 + YWQI LD VG ++ E IVD+GTS IT P+D + ++ + P Sbjct: 309 EKLNHDLYWQITLDA-HVGNIML---EKANCIVDSGTSAITVPTDFLNKMLQNLDVIKVP 364 Query: 306 VDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAG 365 Y C N + +P FT YTL P Y G C GLD P Sbjct: 365 FLPFYVTLCNN-SKLPTFEFTSENGKYTLEPEYYLQHIEDVGPGLCMLNIIGLDFPVPT- 422 Query: 366 PLWILGDVFIRQFYSVFDRGNNRVGLAPA 394 +ILGD F+R++++VFD N+ VG+A A Sbjct: 423 --FILGDPFMRKYFTVFDYDNHSVGIALA 449 >1MIQ-A nrPDB Length = 375 Score = 345 bits (884), Expect = 2e-95, Method: Composition-based stats. Identities = 101/329 (30%), Positives = 156/329 (47%), Gaps = 15/329 (4%) Query: 70 LINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYS 129 L + ++ ++G +G Q F +IFDTGS+NLWVPS C S C + + S+S +Y Sbjct: 56 LDDVANIMFYGEGEVGDNHQKFMLIFDTGSANLWVPSKKCNSSGCSIKNLYDSSKSKSYE 115 Query: 130 QPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDA--EFDGILGL 187 + G I YG+G++ G D V++ L++ +F E + + EFDGILGL Sbjct: 116 KDGTKVDITYGSGTVKGFFSKDLVTLGHLSMP-YKFIEVTDTDDLEPIYSSVEFDGILGL 174 Query: 188 GYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNW 247 G+ L++G + P+ + QN +D +F+ Y+ + L GG + + G++ + Sbjct: 175 GWKDLSIGSIDPIVVELKNQNKIDNALFTFYLPVHDVHA--GYLTIGGIEEKFYEGNITY 232 Query: 248 VPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIG--AAP 305 + YWQI LD + G M E IVD+GT+ IT PS+ + + + P Sbjct: 233 EKLNHDLYWQIDLD-VHFGKQTM---EKANVIVDSGTTTITAPSEFLNKFFANLNVIKVP 288 Query: 306 VDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAG 365 Y C N MP + F YTL P Y C +DI Sbjct: 289 FLPFYVTTCDN-KEMPTLEFKSANNTYTLEPEYYMNPILEVDDTLCMITMLPVDIDSNT- 346 Query: 366 PLWILGDVFIRQFYSVFDRGNNRVGLAPA 394 +ILGD F+R++++VFD VG A A Sbjct: 347 --FILGDPFMRKYFTVFDYDKESVGFAIA 373 >5BWY-A nrPDB Length = 376 Score = 344 bits (883), Expect = 3e-95, Method: Composition-based stats. Identities = 111/329 (33%), Positives = 169/329 (51%), Gaps = 15/329 (4%) Query: 70 LINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYS 129 L+++ ++ ++G +G Q FT I DTGS+NLWVPSV CT+ C T + S+S TY Sbjct: 55 LVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTTAGCLTKHLYDSSKSRTYE 114 Query: 130 QPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPG--QTFVDAEFDGILGL 187 + G + Y +G++SG D V+V L++ +F E + G T+ + FDGILGL Sbjct: 115 KDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLP-YKFIEVIDTNGFEPTYTASTFDGILGL 173 Query: 188 GYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNW 247 G+ L++G V P+ + QN ++ +F+ Y+ + + L GG + + G L + Sbjct: 174 GWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHT--GFLTIGGIEERFYEGPLTY 231 Query: 248 VPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIG--AAP 305 + YWQI LD VG ++ E IVD+GTS IT P+D + ++ + P Sbjct: 232 EKLNHDLYWQITLDA-HVGNIML---EKANCIVDSGTSAITVPTDFLNKMLQNLDVIKVP 287 Query: 306 VDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAG 365 Y C N + +P FT YTL P Y G C GLD P Sbjct: 288 FLPFYVTLCNN-SKLPTFEFTSENGKYTLEPEYYLQHIEDVGPGLCMLNIIGLDFPVPT- 345 Query: 366 PLWILGDVFIRQFYSVFDRGNNRVGLAPA 394 +ILGD F+R++++VFD N+ VG+A A Sbjct: 346 --FILGDPFMRKYFTVFDYDNHSVGIALA 372 >3QS1-A nrPDB Length = 336 Score = 343 bits (880), Expect = 7e-95, Method: Composition-based stats. Identities = 104/342 (30%), Positives = 165/342 (48%), Gaps = 15/342 (4%) Query: 57 TESCSMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKT 116 + + L + ++ Y+G IG Q F IFDTGS+NLWVPS C + CKT Sbjct: 2 QKPHLGNAGDSVTLNDVANVMYYGEAQIGDNKQKFAFIFDTGSANLWVPSAQCNTIGCKT 61 Query: 117 HSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQT- 175 + + ++S TY + G + Y +G++SG D V++ L+ +F E G Sbjct: 62 KNLYDSNKSKTYEKDGTKVEMNYVSGTVSGFFSKDIVTIANLSFP-YKFIEVTDTNGFEP 120 Query: 176 -FVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFG 234 + +FDGI+GLG+ L++G V PV + QN ++ +F+ Y+ + + L G Sbjct: 121 AYTLGQFDGIVGLGWKDLSIGSVDPVVVELKNQNKIEQAVFTFYLPFDDKHK--GYLTIG 178 Query: 235 GYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKI 294 G + + G L + + YWQ+ LD + G + E AIVD+GTS IT P++ + Sbjct: 179 GIEDRFYEGQLTYEKLNHDLYWQVDLD-LHFGNLTV---EKATAIVDSGTSSITAPTEFL 234 Query: 295 KQLQNAIGAA--PVDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCS 352 + + P Y C N +P + F YTL P Y F G+ C Sbjct: 235 NKFFEGLDVVKIPFLPLYITTCNN-PKLPTLEFRSATNVYTLEPEYYLQQIFDFGISLCM 293 Query: 353 SGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPA 394 +D++ +ILGD F+R++++VFD N+ VG A A Sbjct: 294 VSIIPVDLNKNT---FILGDPFMRKYFTVFDYDNHTVGFALA 332 >2ANL-A nrPDB Length = 327 Score = 343 bits (880), Expect = 8e-95, Method: Composition-based stats. Identities = 101/328 (30%), Positives = 156/328 (47%), Gaps = 13/328 (3%) Query: 70 LINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYS 129 L + ++ ++G +G Q F +IFDTGS+NLWVPS C S C T + S+S +Y Sbjct: 8 LDDVANLMFYGEGEVGDNHQKFMLIFDTGSANLWVPSKKCNSIGCSTKHLYDSSKSKSYE 67 Query: 130 QPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGES-VTEPGQTFVDAEFDGILGLG 188 + G I YG+G++ G D V++ L++ + + + + AEFDGILGLG Sbjct: 68 KDGTKVEITYGSGTVRGFFSKDLVTLGYLSLPYKFIEVTDTDDLEPLYTAAEFDGILGLG 127 Query: 189 YPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWV 248 + L++G + P+ + QN +D +F+ Y+ + + L GG + + G L + Sbjct: 128 WKDLSIGSIDPIVVELKNQNKIDQALFTFYLPVHDKHS--GYLTIGGIEEKFYEGELTYE 185 Query: 249 PVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIG--AAPV 306 + +WQ+ LD + G T M E IVD+GTS IT P+ I + + P Sbjct: 186 KLNHDLFWQVDLD-VNFGKTSM---EKANVIVDSGTSTITAPTSFINKFFKDLNVIKVPF 241 Query: 307 DGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGP 366 Y C N MP + F YTL P Y C +DI Sbjct: 242 LPFYITTCNN-KDMPTLEFKSANNTYTLEPEYYMEPLLDIDDTLCMLYILPVDIDKNT-- 298 Query: 367 LWILGDVFIRQFYSVFDRGNNRVGLAPA 394 +ILGD F+R++++VFD +G A A Sbjct: 299 -FILGDPFMRKYFTVFDYDKESIGFAVA 325 >1QS8-A nrPDB Length = 329 Score = 343 bits (879), Expect = 9e-95, Method: Composition-based stats. Identities = 101/329 (30%), Positives = 156/329 (47%), Gaps = 15/329 (4%) Query: 70 LINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYS 129 L + ++ ++G +G Q F +IFDTGS+NLWVPS C S C + + S+S +Y Sbjct: 10 LDDVANIMFYGEGEVGDNHQKFMLIFDTGSANLWVPSKKCNSSGCSIKNLYDSSKSKSYE 69 Query: 130 QPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGES--VTEPGQTFVDAEFDGILGL 187 + G I YG+G++ G D V++ L++ +F E + + EFDGILGL Sbjct: 70 KDGTKVDITYGSGTVKGFFSKDLVTLGHLSMP-YKFIEVIDTDDLEPIYSSVEFDGILGL 128 Query: 188 GYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNW 247 G+ L++G + P+ + QN +D +F+ Y+ + L GG + + G++ + Sbjct: 129 GWKDLSIGSIDPIVVELKNQNKIDNALFTFYLPVHDVHA--GYLTIGGIEEKFYEGNITY 186 Query: 248 VPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIG--AAP 305 + YWQI LD + G M E IVD+GT+ IT PS+ + + + P Sbjct: 187 EKLNHDLYWQIDLD-VHFGKQTM---EKANVIVDSGTTTITAPSEFLNKFFANLNVIKVP 242 Query: 306 VDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAG 365 Y C N MP + F YTL P Y C +DI Sbjct: 243 FLPFYVTTCDN-KEMPTLEFKSANNTYTLEPEYYMNPILEVDDTLCMITMLPVDIDSNT- 300 Query: 366 PLWILGDVFIRQFYSVFDRGNNRVGLAPA 394 +ILGD F+R++++VFD VG A A Sbjct: 301 --FILGDPFMRKYFTVFDYDKESVGFAIA 327 >1XDH-A nrPDB Length = 331 Score = 341 bits (875), Expect = 3e-94, Method: Composition-based stats. Identities = 111/329 (33%), Positives = 169/329 (51%), Gaps = 15/329 (4%) Query: 70 LINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYS 129 L+++ ++ ++G +G Q FT I DTGS+NLWVPSV CT+ C T + S+S TY Sbjct: 10 LVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTTAGCLTKHLYDSSKSRTYE 69 Query: 130 QPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPG--QTFVDAEFDGILGL 187 + G + Y +G++SG D V+V L++ +F E + G T+ + FDGILGL Sbjct: 70 KDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLP-YKFIEVIDTNGFEPTYTASTFDGILGL 128 Query: 188 GYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNW 247 G+ L++G V P+ + QN ++ +F+ Y+ + + L GG + + G L + Sbjct: 129 GWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHT--GFLTIGGIEERFYEGPLTY 186 Query: 248 VPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIG--AAP 305 + YWQI LD VG ++ E IVD+GTS IT P+D + ++ + P Sbjct: 187 EKLNHDLYWQITLDA-HVGNIML---EKANCIVDSGTSAITVPTDFLNKMLQNLDVIKVP 242 Query: 306 VDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAG 365 Y C N + +P FT YTL P Y G C GLD P Sbjct: 243 FLPFYVTLCNN-SKLPTFEFTSENGKYTLEPEYYLQHIEDVGPGLCMLNIIGLDFPVPT- 300 Query: 366 PLWILGDVFIRQFYSVFDRGNNRVGLAPA 394 +ILGD F+R++++VFD N+ VG+A A Sbjct: 301 --FILGDPFMRKYFTVFDYDNHSVGIALA 327 >5JOD-A nrPDB Length = 375 Score = 332 bits (851), Expect = 2e-91, Method: Composition-based stats. Identities = 106/344 (30%), Positives = 162/344 (47%), Gaps = 15/344 (4%) Query: 55 QFTESCSMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPAC 114 + ++ L + ++ ++G IG+ Q F IFDTGS+NLWVPSV C S C Sbjct: 40 YAQKGYLGSENDSIELDDVANLMFYGEGQIGTNKQPFMFIFDTGSANLWVPSVNCDSIGC 99 Query: 115 KTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESV--TEP 172 T + S S +Y + G I YG+G++ G D +S+ L++ +F E + Sbjct: 100 STKHLYDASASKSYEKDGTKVEISYGSGTVRGYFSKDVISLGDLSLP-YKFIEVTDADDL 158 Query: 173 GQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELI 232 + +EFDGILGLG+ L++G + PV + QN +D +F+ Y+ + + L Sbjct: 159 EPIYSGSEFDGILGLGWKDLSIGSIDPVVVELKKQNKIDNALFTFYLPVHDKHV--GYLT 216 Query: 233 FGGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSD 292 GG + + G L + + YWQI LD I G VM + A+VD+GTS IT P+ Sbjct: 217 IGGIESDFYEGPLTYEKLNHDLYWQIDLD-IHFGKYVM---QKANAVVDSGTSTITAPTS 272 Query: 293 KIKQLQNAIG--AAPVDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQF 350 + + + P Y C N + +P + F YTL P Y Sbjct: 273 FLNKFFRDMNVIKVPFLPLYVTTCDN-DDLPTLEFHSRNNKYTLEPEFYMDPLSDIDPAL 331 Query: 351 CSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPA 394 C +DI +ILGD F+R++++VFD VG A A Sbjct: 332 CMLYILPVDIDDNT---FILGDPFMRKYFTVFDYEKESVGFAVA 372 >5I70-B nrPDB Length = 328 Score = 331 bits (849), Expect = 3e-91, Method: Composition-based stats. Identities = 106/329 (32%), Positives = 159/329 (48%), Gaps = 15/329 (4%) Query: 70 LINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYS 129 L + ++ ++G IG+ Q F IFDTGS+NLWVPSV C S C T + S S +Y Sbjct: 8 LDDVANLMFYGEGQIGTNKQPFMFIFDTGSANLWVPSVNCDSIGCSTKHLYDASASKSYE 67 Query: 130 QPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESV--TEPGQTFVDAEFDGILGL 187 + G I YG+G++ G D +S+ L++ +F E + + +EFDGILGL Sbjct: 68 KDGTKVEISYGSGTVRGYFSKDVISLGDLSLP-YKFIEVTDADDLEPIYSGSEFDGILGL 126 Query: 188 GYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNW 247 G+ L++G + PV + QN +D +F+ Y+ + + L GG + + G L + Sbjct: 127 GWKDLSIGSIDPVVVELKKQNKIDNALFTFYLPVHDKHV--GYLTIGGIESDFYEGPLTY 184 Query: 248 VPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIG--AAP 305 + YWQI LD I G VM + A+VD+GTS IT P+ + + + P Sbjct: 185 EKLNHDLYWQIDLD-IHFGKYVM---QKANAVVDSGTSTITAPTSFLNKFFRDMNVIKVP 240 Query: 306 VDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAG 365 Y C N + +P + F YTL P Y C +DI Sbjct: 241 FLPLYVTTCDN-DDLPTLEFHSRNNKYTLEPEFYMDPLSDIDPALCMLYILPVDIDDNT- 298 Query: 366 PLWILGDVFIRQFYSVFDRGNNRVGLAPA 394 +ILGD F+R++++VFD VG A A Sbjct: 299 --FILGDPFMRKYFTVFDYEKESVGFAVA 325 >4OC6-B nrPDB Length = 243 Score = 316 bits (809), Expect = 1e-86, Method: Composition-based stats. Identities = 124/241 (51%), Positives = 167/241 (69%), Gaps = 1/241 (0%) Query: 156 EGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMF 215 G+ V Q FGE+ +PG TF+ A+FDGILG+ YP ++V V PVFDN+M Q LVD +F Sbjct: 1 GGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIF 60 Query: 216 SVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEG 275 S Y+S +P+ G EL+ GG D ++ GSL+++ VT++AYWQ+ LD ++V + C EG Sbjct: 61 SFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKEG 120 Query: 276 CQAIVDTGTSLITGPSDKIKQLQNAIGAAP-VDGEYAVECANLNVMPDVTFTINGVPYTL 334 C+AIVDTGTSL+ GP D++++LQ AIGA P + GEY + C ++ +P +T + G Y L Sbjct: 121 CEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKL 180 Query: 335 SPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPA 394 SP YTL G C SGF G+DI PP+GPLWILGDVFI ++Y+VFDR NNRVG A A Sbjct: 181 SPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGFAEA 240 Query: 395 V 395 Sbjct: 241 A 241 >1QDM-A nrPDB Length = 478 Score = 312 bits (800), Expect = 2e-85, Method: Composition-based stats. Identities = 128/298 (42%), Positives = 182/298 (61%), Gaps = 8/298 (2%) Query: 22 HRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAKEPLINYLDMEYFGT 81 R+ L++ P + + R + LS + S ++ L NY++ +YFG Sbjct: 1 VRIALKKRP-IDRNSRVATGLS--GGEEQPLLSGANPLRSEEEGDIVALKNYMNAQYFGE 57 Query: 82 ISIGSPPQNFTVIFDTGSSNLWVPSVYCT-SPACKTHSRFQPSQSSTYSQPGQSFSIQYG 140 I +G+PPQ FTVIFDTGSSNLWVPS C S AC HSR++ SSTY + G+ +IQYG Sbjct: 58 IGVGTPPQKFTVIFDTGSSNLWVPSAKCYFSIACYLHSRYKAGASSTYKKNGKPAAIQYG 117 Query: 141 TGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPV 200 TGS++G D V+V L V Q+F E+ EPG TF+ A+FDGILGLG+ ++VG PV Sbjct: 118 TGSIAGYFSEDSVTVGDLVVKDQEFIEATKEPGITFLVAKFDGILGLGFKEISVGKAVPV 177 Query: 201 FDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIAL 260 + M+ Q LV P+FS +++ + + G G E+IFGG D H+ G +VPVT++ YWQ + Sbjct: 178 WYKMIEQGLVSDPVFSFWLNRHVDEGEGGEIIFGGMDPKHYVGEHTYVPVTQKGYWQFDM 237 Query: 261 DNIQVGG-TVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVDGEYAVECANL 317 ++ VGG + FC+ GC AI D+GTSL+ GP+ I ++ IGAA G + EC + Sbjct: 238 GDVLVGGKSTGFCAGGCAAIADSGTSLLAGPTAIITEINEKIGAA---GVVSQECKTI 292 Score = 121 bits (303), Expect = 6e-28, Method: Composition-based stats. Identities = 43/88 (48%), Positives = 53/88 (60%) Query: 308 GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPL 367 GE AV+C +L MPD+ FTI G + L P Y L C SGF +DI PP GPL Sbjct: 391 GESAVDCGSLGSMPDIEFTIGGKKFALKPEEYILKVGEGAAAQCISGFTAMDIPPPRGPL 450 Query: 368 WILGDVFIRQFYSVFDRGNNRVGLAPAV 395 WILGDVF+ +++VFD G R+G A A Sbjct: 451 WILGDVFMGPYHTVFDYGKLRIGFAKAA 478 >3QVI-A nrPDB Length = 451 Score = 310 bits (794), Expect = 7e-85, Method: Composition-based stats. Identities = 93/331 (28%), Positives = 157/331 (47%), Gaps = 15/331 (4%) Query: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSST 127 L + ++ FG +G Q F +F T SSN+WVPS+ CTS +C++ + + S+S T Sbjct: 129 VELKDLANVLSFGEAKLGDNGQKFNFLFHTASSNVWVPSIKCTSESCESKNHYDSSKSKT 188 Query: 128 YSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPG--QTFVDAEFDGIL 185 Y + + G++SGI D V++ L+V +F E G + +++ DG+ Sbjct: 189 YEKDDTPVKLTSKAGTISGIFSKDLVTIGKLSVP-YKFIEMTEIVGFEPFYSESDVDGVF 247 Query: 186 GLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245 GLG+ L++G + P + QN ++ ++S+Y+ PE L GG + F G L Sbjct: 248 GLGWKDLSIGSIDPYIVELKTQNKIEQAVYSIYLP--PENKNKGYLTIGGIEERFFDGPL 305 Query: 246 NWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQN--AIGA 303 N+ + WQ+ LD + G S+ I+D+ TS+IT P++ Q ++ Sbjct: 306 NYEKLNHDLMWQVDLD-VHFGN---VSSKKANVILDSATSVITVPTEFFNQFVESASVFK 361 Query: 304 APVDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPP 363 P Y C N +P + + YTL P Y C +D+ Sbjct: 362 VPFLSLYVTTCGNTK-LPTLEYRSPNKVYTLEPKQYLEPLENIFSALCMLNIVPIDL--- 417 Query: 364 AGPLWILGDVFIRQFYSVFDRGNNRVGLAPA 394 ++LGD F+R++++V+D N+ VG A A Sbjct: 418 EKNTFVLGDPFMRKYFTVYDYDNHTVGFALA 448 >3FNT-A nrPDB Length = 332 Score = 306 bits (783), Expect = 1e-83, Method: Composition-based stats. Identities = 93/331 (28%), Positives = 157/331 (47%), Gaps = 15/331 (4%) Query: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSST 127 L + ++ FG +G Q F +F T SSN+WVPS+ CTS +C++ + + S+S T Sbjct: 10 VELKDLANVLSFGEAKLGDNGQKFNFLFHTASSNVWVPSIKCTSESCESKNHYDSSKSKT 69 Query: 128 YSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPG--QTFVDAEFDGIL 185 Y + + G++SGI D V++ L+V +F E G + +++ DG+ Sbjct: 70 YEKDDTPVKLTSKAGTISGIFSKDLVTIGKLSVP-YKFIEMTEIVGFEPFYSESDVDGVF 128 Query: 186 GLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245 GLG+ L++G + P + QN ++ ++S+Y+ PE L GG + F G L Sbjct: 129 GLGWKDLSIGSIDPYIVELKTQNKIEQAVYSIYLP--PENKNKGYLTIGGIEERFFDGPL 186 Query: 246 NWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQN--AIGA 303 N+ + WQ+ LD + G S+ I+D+ TS+IT P++ Q ++ Sbjct: 187 NYEKLNHDLMWQVDLD-VHFGN---VSSKKANVILDSATSVITVPTEFFNQFVESASVFK 242 Query: 304 APVDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPP 363 P Y C N +P + + YTL P Y C +D+ Sbjct: 243 VPFLSLYVTTCGNTK-LPTLEYRSPNKVYTLEPKQYLEPLENIFSALCMLNIVPIDL--- 298 Query: 364 AGPLWILGDVFIRQFYSVFDRGNNRVGLAPA 394 ++LGD F+R++++V+D N+ VG A A Sbjct: 299 EKNTFVLGDPFMRKYFTVYDYDNHTVGFALA 329 >1B5F-A nrPDB Length = 239 Score = 293 bits (749), Expect = 1e-79, Method: Composition-based stats. Identities = 112/242 (46%), Positives = 150/242 (61%), Gaps = 6/242 (2%) Query: 64 QSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC-TSPACKTHSRFQP 122 SA L N D YFG I IG+PPQ FTVIFDTGSS LWVPS C S AC+ HS ++ Sbjct: 1 GSAVVALTNDRDTSYFGEIGIGTPPQKFTVIFDTGSSVLWVPSSKCINSKACRAHSMYES 60 Query: 123 SQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFD 182 S SSTY + G +I YGTGS++G D V++ L V Q F E+ E F+ FD Sbjct: 61 SDSSTYKENGTFGAIIYGTGSITGFFSQDSVTIGDLVVKEQDFIEATDEADNVFLHRLFD 120 Query: 183 GILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFS 242 GILGL + +++V PV+ NM+ Q LV FS +++ N + G EL+FGG D +HF Sbjct: 121 GILGLSFQTISV----PVWYNMLNQGLVKERRFSFWLNRNVDEEEGGELVFGGLDPNHFR 176 Query: 243 GSLNWVPVTKQAYWQIALDNIQVGG-TVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAI 301 G +VPVT Q YWQ + ++ +G + FC+ GCQA D+GTSL++GP+ + Q+ +AI Sbjct: 177 GDHTYVPVTYQYYWQFGIGDVLIGDKSTGFCAPGCQAFADSGTSLLSGPTAIVTQINHAI 236 Query: 302 GA 303 GA Sbjct: 237 GA 238 >2ASI-A nrPDB Length = 361 Score = 276 bits (705), Expect = 2e-74, Method: Composition-based stats. Identities = 105/362 (29%), Positives = 159/362 (43%), Gaps = 37/362 (10%) Query: 60 CSMDQSAKEPLINYLD-MEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCT-SPACKTH 117 + D S P D EY +SIG+P Q+F ++FDTGSS+ WVP CT S C Sbjct: 1 AAADGSVDTPGYYDFDLEEYAIPVSIGTPGQDFLLLFDTGSSDTWVPHKGCTKSEGCVGS 60 Query: 118 SRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTF- 176 F PS SST+ + +I YGTG +G+ D +++ +TV Q G T Sbjct: 61 RFFDPSASSTFKATNYNLNITYGTGGANGLYFEDSIAIGDITVTKQILAYVDNVRGPTAE 120 Query: 177 ----VDAEFDGILGLGYPSLAV------GGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGG 226 D DG+ G YP V N+ Q L+ P+FSVYM++N Sbjct: 121 QSPNADIFLDGLFGAAYPDNTAMEAEYGSTYNTVHVNLYKQGLISSPLFSVYMNTNS--- 177 Query: 227 AGSELIFGGYDHSHFSGSLNWVPVTKQ----AYWQIALDNIQVGGTVMFCSEGCQAI-VD 281 E++FGG +++ G + + V + +W + I V G+ QA +D Sbjct: 178 GTGEVVFGGVNNTLLGGDIAYTDVMSRYGGYYFWDAPVTGITVDGSAAVRFSRPQAFTID 237 Query: 282 TGTSLITGPSDKIKQLQNAI--GAAPVDGEYAVECANLNV--------MPDVTFTINGVP 331 TGT+ PS ++ A A + V CA+ M + + + Sbjct: 238 TGTNFFIMPSSAASKIVKAALPDATETQQGWVVPCASYQNSKSTISIVMQKSGSSSDTIE 297 Query: 332 YTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGL 391 ++ P + LL + C I P G +I+G++F+R F +V+D GNNR+G Sbjct: 298 ISV-PVSKMLLPVDQSNETCM-----FIILPDGGNQYIVGNLFLRFFVNVYDFGNNRIGF 351 Query: 392 AP 393 AP Sbjct: 352 AP 353 >1UH8-A nrPDB Length = 325 Score = 273 bits (697), Expect = 1e-73, Method: Composition-based stats. Identities = 119/337 (35%), Positives = 183/337 (54%), Gaps = 19/337 (5%) Query: 64 QSAKEPLINY-LDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQP 122 P+ +Y D+EY+G ++IG+P + F + FDTGSS+LW+ S CT+ + +++ P Sbjct: 2 GVGTVPMTDYGNDIEYYGQVTIGTPGKKFNLDFDTGSSDLWIASTLCTNCGSR-QTKYDP 60 Query: 123 SQSSTYSQPGQSFSIQYGTG-SLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEF 181 +QSSTY G+++SI YG G S SGI+ D V++ GL + GQ E +F Sbjct: 61 NQSSTYQADGRTWSISYGDGSSASGILAKDNVNLGGLLIKGQT-IELAKREAASFASGPN 119 Query: 182 DGILGLGYPSL-AVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSH 240 DG+LGLG+ ++ V GV DN+++Q L+ P+F VY+ + G G E IFGGYD + Sbjct: 120 DGLLGLGFDTITTVRGVKTPMDNLISQGLISRPIFGVYL-GKAKNGGGGEYIFGGYDSTK 178 Query: 241 FSGSLNWVPV-TKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQN 299 F GSL VP+ + +W I +D VG + + S I+DTGT+L+ P++ + Sbjct: 179 FKGSLTTVPIDNSRGWWGITVDRATVGTSTVASS--FDGILDTGTTLLILPNNIAASVAR 236 Query: 300 AIGAAPV-DGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGL 358 A GA+ DG Y + C P + F+ING + +SP + +F G G+ Sbjct: 237 AYGASDNGDGTYTISCDTSRFKP-LVFSINGASFQVSPDSLVFEEF-QGQCIAGFGYGNW 294 Query: 359 DIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPAV 395 D I+GD F++ Y VF++G V +AP Sbjct: 295 DFA-------IIGDTFLKNNYVVFNQGVPEVQIAPVA 324 >3TPL-A nrPDB Length = 433 Score = 268 bits (686), Expect = 2e-72, Method: Composition-based stats. Identities = 96/352 (27%), Positives = 157/352 (44%), Gaps = 41/352 (11%) Query: 78 YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137 Y+ +++GSPPQ ++ DTGSSN V + +P H +Q SSTY + + Sbjct: 54 YYVEMTVGSPPQTLNILVDTGSSNFAVGA----APHPFLHRYYQRQLSSTYRDLRKGVYV 109 Query: 138 QYGTGSLSGIIGADQVSV-EGLTVVGQQFGESVTEPGQTFVD-AEFDGILGLGYPSLAV- 194 Y G+ +G +G D VS+ G V + ++TE + F++ + ++GILGL Y +A Sbjct: 110 PYTQGAWAGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARP 169 Query: 195 -GGVTPVFDNMMAQ----NLVDLPMFSVYMSSNPE---GGAGSELIFGGYDHSHFSGSLN 246 + P FD+++ Q NL L + N G +I GG DHS ++GSL Sbjct: 170 DDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLW 229 Query: 247 WVPVTKQAYWQIALDNIQVGGT--VMFCSEGC--QAIVDTGTSLITGPSDKIKQLQNAIG 302 + P+ ++ Y+++ + +++ G M C E ++IVD+GT+ + P + +I Sbjct: 230 YTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIK 289 Query: 303 AAPV-----DGEYAVE---CANLNVMPDVTF-----------TINGVPYTLSPTAYTLLD 343 AA DG + E C P F T T+ P Y L Sbjct: 290 AASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQY--LR 347 Query: 344 FVDGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPAV 395 V+ + I + ++G V + FY VFDR R+G A + Sbjct: 348 PVEDVATSQDDCYKFAISQSSTGT-VMGAVIMEGFYVVFDRARKRIGFAVSA 398 >3LIZ-A nrPDB Length = 334 Score = 263 bits (672), Expect = 1e-70, Method: Composition-based stats. Identities = 92/333 (27%), Positives = 149/333 (44%), Gaps = 27/333 (8%) Query: 73 YLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPAC-----KTHSRFQPSQSST 127 +++ +Y G IG+ QNF +FD+ S N+ V S C AC + + + +P Sbjct: 16 FINTQYAGITKIGN--QNFLTVFDSTSCNVVVASQECVGGACVCPNLQKYEKLKPK---- 69 Query: 128 YSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGL 187 Y G + TGS G D +++ LT QQ E Q D ++G+ Sbjct: 70 YISDGNVQVKFFDTGSAVGRGIEDSLTISQLT-TSQQDIVLADELSQEVCILSADVVVGI 128 Query: 188 GYPSL-AVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLN 246 P V +N + +NL+ P+FS++ + +G E+IFGG D + G Sbjct: 129 AAPGCPNALKGKTVLENFVEENLIA-PVFSIHHARFQDGEHFGEIIFGGSDWKYVDGEFT 187 Query: 247 WVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAA-- 304 +VP+ W+ LD +++G T + G QAI+DT ++I GP + + AIG Sbjct: 188 YVPLVGDDSWKFRLDGVKIGDTTVA-PAGTQAIIDTSKAIIVGPKAYVNPINEAIGCVVE 246 Query: 305 --PVDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHP 362 ++C+ + +PDVTF ING + +S Y + C SGFQ Sbjct: 247 KTTTRRICKLDCSKIPSLPDVTFVINGRNFNISSQYYIQQNG----NLCYSGFQPC---- 298 Query: 363 PAGPLWILGDVFIRQFYSVFDRGNNRVGLAPAV 395 + +GD F+ +YS F+ N +G +V Sbjct: 299 GHSDHFFIGDFFVDHYYSEFNWENKTMGFGRSV 331 >2QZW-A nrPDB Length = 341 Score = 259 bits (663), Expect = 1e-69, Method: Composition-based stats. Identities = 97/338 (28%), Positives = 150/338 (44%), Gaps = 33/338 (9%) Query: 71 INYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVP--SVYC-------TSPACKTHSRFQ 121 +N + Y I+IGS Q F VI DTGSS+LWVP SV C ++ CK + Sbjct: 7 LNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYT 66 Query: 122 PSQSSTYSQPGQSFSIQYGTGSLS-GIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAE 180 P S+T G F I YG GS S G + D V G ++ Q F + Sbjct: 67 PKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP------ 120 Query: 181 FDGILGLGYPSL-AVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHS 239 GILG+GY + A G V + Q ++ +S+Y+ N A ++IFGG D + Sbjct: 121 -QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYL--NSPNAATGQIIFGGVDKA 177 Query: 240 HFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQN 299 +SGSL VPVT +I L++++ G + + ++D+GT++ D + + + Sbjct: 178 KYSGSLIAVPVTSDRELRITLNSLKAVGKNI--NGNIDVLLDSGTTITYLQQDVAQDIID 235 Query: 300 AIGAA-PVDG----EYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSG 354 A A DG Y +C + D F N ++ + +T Q Sbjct: 236 AFQAELKSDGQGHTFYVTDCQTSGTV-DFNFD-NNAKISVPASEFTAPLSYANGQ----P 289 Query: 355 FQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLA 392 + + ILGD F+R Y V+D ++++ LA Sbjct: 290 YPKCQLLLGISDANILGDNFLRSAYLVYDLDDDKISLA 327 >1MPP-A nrPDB Length = 361 Score = 258 bits (658), Expect = 4e-69, Method: Composition-based stats. Identities = 105/359 (29%), Positives = 158/359 (44%), Gaps = 37/359 (10%) Query: 63 DQSAKEPLINYLD-MEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC-TSPACKTHSRF 120 D S P + D EY +SIG+P Q+F ++FDTGSS+ WVP C S C F Sbjct: 4 DGSVDTPGLYDFDLEEYAIPVSIGTPGQDFYLLFDTGSSDTWVPHKGCDNSEGCVGKRFF 63 Query: 121 QPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAE 180 PS SST+ + + +I YGTG +GI D ++V G TV Q G T + Sbjct: 64 DPSSSSTFKETDYNLNITYGTGGANGIYFRDSITVGGATVKQQTLAYVDNVSGPTAEQSP 123 Query: 181 -----FDGILGLGYPSLAV------GGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGS 229 DGI G YP V N+ Q L+ P+FSVYM++N GG Sbjct: 124 DSELFLDGIFGAAYPDNTAMEAEYGDTYNTVHVNLYKQGLISSPVFSVYMNTNDGGGQVV 183 Query: 230 ELIFGGYDHSHFSGSLNWVPVTKQA----YWQIALDNIQVGGTVMFCSEGCQAI-VDTGT 284 +++ G + + V K +W + +++ G+ +G QA +DTGT Sbjct: 184 FGG---VNNTLLGGDIQYTDVLKSRGGYFFWDAPVTGVKIDGSDAVSFDGAQAFTIDTGT 240 Query: 285 SLITGPSDKIKQLQNAI--GAAPVDGEYAVECANLNVMPDVTFTI-------NGVPYTLS 335 + PS +++ A A Y V C+ TF++ + +S Sbjct: 241 NFFIAPSSFAEKVVKAALPDATESQQGYTVPCSKYQDSKT-TFSLVLQKSGSSSDTIDVS 299 Query: 336 -PTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAP 393 P + LL + C + P G +I+G++F+R F +V+D G NR+G AP Sbjct: 300 VPISKMLLPVDKSGETCM-----FIVLPDGGNQFIVGNLFLRFFVNVYDFGKNRIGFAP 353 >3ZKX-A nrPDB Length = 386 Score = 256 bits (655), Expect = 9e-69, Method: Composition-based stats. Identities = 91/346 (26%), Positives = 151/346 (43%), Gaps = 39/346 (11%) Query: 78 YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137 Y+ + IG+PPQ ++ DTGSSN V P + F +SSTY G ++ Sbjct: 18 YYLEMLIGTPPQKLQILVDTGSSNFAVAGT----PHSYIDTYFDTERSSTYRSKGFDVTV 73 Query: 138 QYGTGSLSGIIGADQVSV-EGLTVVGQQFGESVTEPGQTFVDA-EFDGILGLGYPSLAVG 195 +Y GS +G +G D V++ +G ++ E F+ +++GILGL Y +LA Sbjct: 74 KYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKP 133 Query: 196 G--VTPVFDNMMAQ----NLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVP 249 + FD+++ Q N+ + M + G G L+ GG + S + G + + P Sbjct: 134 SSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTP 193 Query: 250 VTKQAYWQIALDNIQVGGTV--MFCSEGC--QAIVDTGTSLITGPSDKIKQLQNAIGAAP 305 + ++ Y+QI + +++GG + C E +AIVD+GT+L+ P + A+ A Sbjct: 194 IKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARAS 253 Query: 306 -----VDGEYA---VECANLNVMPDVTF-----------TINGVPYTLSPTAYTLLDFVD 346 DG + + C + P F + T+ P Y Sbjct: 254 LIPAFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENSSRSFRITILPQLYIQPMMGA 313 Query: 347 GMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLA 392 G+ + F I P L ++G + FY +FDR RVG A Sbjct: 314 GLNYECYRFG---ISPSTNAL-VIGATVMEGFYVIFDRAQKRVGFA 355 >3PVK-A nrPDB Length = 342 Score = 255 bits (651), Expect = 3e-68, Method: Composition-based stats. Identities = 95/346 (27%), Positives = 150/346 (43%), Gaps = 35/346 (10%) Query: 64 QSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC---------TSPAC 114 Q+ L N + Y I++GS Q VI DTGSS+LWVP V T+ C Sbjct: 1 QAVPVTLHNE-QVTYAADITVGSNNQKLNVIVDTGSSDLWVPDVNVDCQVTYSDQTADFC 59 Query: 115 KTHSRFQPSQSSTYSQPGQSFSIQYGTGSLS-GIIGADQVSVEGLTVVGQQFGESVTEPG 173 K + PS SS F I YG GS S G + D V G+++ Q + + Sbjct: 60 KQKGTYDPSGSSASQDLNTPFKIGYGDGSSSQGTLYKDTVGFGGVSIKNQVLADVDSTSI 119 Query: 174 QTFVDAEFDGILGLGYPSLAVGGV-TPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELI 232 GILG+GY + GG V + Q ++ +S+Y+ N A ++I Sbjct: 120 D-------QGILGVGYKTNEAGGSYDNVPVTLKKQGVIAKNAYSLYL--NSPDAATGQII 170 Query: 233 FGGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSD 292 FGG D++ +SGSL +PVT +I+L +++V G + ++ ++D+GT++ D Sbjct: 171 FGGVDNAKYSGSLIALPVTSDRELRISLGSVEVSGKTIN-TDNVDVLLDSGTTITYLQQD 229 Query: 293 KIKQLQNAIGAAPV-----DGEYAVECANLNVMPDVTFTIN-GVPYTLSPTAYTLLDFVD 346 Q+ A + Y V+C + DV F + ++ + + D Sbjct: 230 LADQIIKAFNGKLTQDSNGNSFYEVDCN---LSGDVVFNFSKNAKISVPASEFAASLQGD 286 Query: 347 GMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLA 392 Q + + ILGD F+R Y V+D +N + LA Sbjct: 287 DGQ----PYDKCQLLFDVNDANILGDNFLRSAYIVYDLDDNEISLA 328 >4B1C-A nrPDB Length = 375 Score = 254 bits (649), Expect = 4e-68, Method: Composition-based stats. Identities = 92/345 (26%), Positives = 152/345 (44%), Gaps = 41/345 (11%) Query: 78 YFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSI 137 Y+ +++GSPPQ ++ DTGSSN V + +P H +Q SSTY + + Sbjct: 20 YYVEMTVGSPPQTLNILVDTGSSNFAVGA----APHPFLHRYYQRQLSSTYRDLRKGVYV 75 Query: 138 QYGTGSLSGIIGADQVSV-EGLTVVGQQFGESVTEPGQTFVD-AEFDGILGLGYPSLAV- 194 Y G G +G D VS+ G V + ++TE + F++ + ++GILGL Y +A Sbjct: 76 PYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARP 135 Query: 195 -GGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQ 253 + P FD+++ Q V +FS+ + G DHS ++GSL + P+ ++ Sbjct: 136 DDSLEPFFDSLVKQTHVP-NLFSLQLCGGGSMIIGGI------DHSLYTGSLWYTPIRRE 188 Query: 254 AYWQIALDNIQVGGT--VMFCSEGC--QAIVDTGTSLITGPSDKIKQLQNAIGAAPV--- 306 Y+++ + +++ G M C E ++IVD+GT+ + P + +I AA Sbjct: 189 WYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEK 248 Query: 307 --DGEYAVE---CANLNVMPDVTF-----------TINGVPYTLSPTAYTLLDFVDGMQF 350 DG + E C P F T T+ P Y L V+ + Sbjct: 249 FPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQY--LRPVEDVAT 306 Query: 351 CSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPAV 395 I + ++G V + FY VFDR R+G A + Sbjct: 307 SQDDCYKFAISQSSTGT-VMGAVIMEGFYVVFDRARKRIGFAVSA 350 >4Y9W-A nrPDB Length = 334 Score = 250 bits (638), Expect = 8e-67, Method: Composition-based stats. Identities = 96/341 (28%), Positives = 148/341 (43%), Gaps = 33/341 (9%) Query: 65 SAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWV--PSVYCTSPACKTHSRFQP 122 S+ + + Y +S+GS Q V+ DTGSS+ WV S C CK + F P Sbjct: 1 SSPSSPLYFEGPSYGIRVSVGSNKQEQQVVLDTGSSDFWVVDSSASCQKGNCKQYGTFDP 60 Query: 123 SQSSTYSQPGQSFSIQYGTGSLS-GIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEF 181 S+++ G SFSI YG S S G G D + + G ++ Q+F + + + Sbjct: 61 HSSTSFKSLGSSFSIGYGDKSSSIGTWGQDTIYLGGTSITNQRFADVTST-------SVN 113 Query: 182 DGILGLGYPSLAVGGVTPVFDN----MMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYD 237 GILG+G + P +DN + Q + +S+Y+ N G A +IFGG D Sbjct: 114 QGILGVG--RVETESANPPYDNVPITLKKQGKIKTNAYSLYL--NSPGAATGTIIFGGVD 169 Query: 238 HSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQL 297 ++ +SG L P+ Y + L ++ G + G +VD+GT++ P + L Sbjct: 170 NAKYSGKLIEEPLVSDRYLAVNLKSLNYNGDN--SNAGFGVVVDSGTTISYLPDSIVDDL 227 Query: 298 QNAIGAA-----PVDGEYAVECANLNVMPDVTFTI-NGVPYTLSPTAYTLLDFVDGMQFC 351 N +GA + Y ++C +FT NG T+ + + L + C Sbjct: 228 ANKVGAYLEPVGLGNELYFIDCNANPQ-GSASFTFDNGAKITVPLSEFVLQSTANA---C 283 Query: 352 SSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLA 392 G Q D ILGD F+R Y VF+ V LA Sbjct: 284 VWGLQSSD---RQNVPPILGDNFLRHAYVVFNLDKETVSLA 321 >2H6T-A nrPDB Length = 340 Score = 246 bits (629), Expect = 1e-65, Method: Composition-based stats. Identities = 96/347 (27%), Positives = 156/347 (44%), Gaps = 39/347 (11%) Query: 64 QSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPA--------CK 115 Q+ LIN + Y I++GS Q TV+ DTGSS+LWVP + A CK Sbjct: 1 QTVPVKLINE-QVSYASDITVGSNKQKLTVVIDTGSSDLWVPDSQVSCQAGQGQDPNFCK 59 Query: 116 THSRFQPSQSSTYSQPGQSFSIQYGTGSLS-GIIGADQVSVEGLTVVGQQFGESVTEPGQ 174 + PS SS+ FSI+YG G+ S G D + G+++ QQF + + Sbjct: 60 NEGTYSPSSSSSSQNLNSPFSIEYGDGTTSQGTWYKDTIGFGGISITKQQFADVTSTSVD 119 Query: 175 TFVDAEFDGILGLGYPSLAVGG-VTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIF 233 GILG+GY + G V + Q ++ +S+Y++S ++IF Sbjct: 120 -------QGILGIGYKTHEAEGNYDNVPVTLKNQGIISKNAYSLYLNSRQ--ATSGQIIF 170 Query: 234 GGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDK 293 GG D++ +SG+L +PVT +I L+ ++V G + + ++D+GT++ Sbjct: 171 GGVDNAKYSGTLIALPVTSDNELRIHLNTVKVAGQSI--NADVDVLLDSGTTITYLQQGV 228 Query: 294 IKQLQNAIGAAPV-----DGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGM 348 Q+ +A + Y V+C NL+ D F N ++ + +T + + Sbjct: 229 ADQVISAFNGQETYDANGNLFYLVDC-NLSGSVDFAFDKN-AKISVPASEFTAPLYTEDG 286 Query: 349 ---QFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLA 392 C F D + ILGD F+R Y V+D +N + LA Sbjct: 287 QVYDQCQLLFGTSDYN-------ILGDNFLRSAYIVYDLDDNEISLA 326 >2QZX-A nrPDB Length = 342 Score = 245 bits (626), Expect = 2e-65, Method: Composition-based stats. Identities = 84/349 (24%), Positives = 147/349 (42%), Gaps = 39/349 (11%) Query: 64 QSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC---------TSPAC 114 L N + Y I++GS Q VI DTGSS+LW+P C Sbjct: 1 GPVAVTLHNEA-ITYTADITVGSDNQKLNVIVDTGSSDLWIPDSNVICIPKWRGDKGDFC 59 Query: 115 KTHSRFQPSQSSTYSQPGQSFSIQYGTGS-LSGIIGADQVSVEGLTVVGQQFGESVTEPG 173 K+ + P+ S T F I+YG GS G + D V + G++V Q F + Sbjct: 60 KSAGSYSPASSRTSQNLNTRFDIKYGDGSYAKGKLYKDTVGIGGVSVRDQLFANVWSTSA 119 Query: 174 QTFVDAEFDGILGLGYPSLAVGGVTPVFDN----MMAQNLVDLPMFSVYMSSNPEGGAGS 229 + GILG+G+ S +DN + Q ++ +S+Y+ N + Sbjct: 120 RK-------GILGIGFQSGEATEFD--YDNLPISLRNQGIIGKAAYSLYL--NSAEASTG 168 Query: 230 ELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITG 289 ++IFGG D + +SGSL +P+T + + L ++ V G + ++D+GT++ Sbjct: 169 QIIFGGIDKAKYSGSLVDLPITSEKKLTVGLRSVNVRGRNVD--ANTNVLLDSGTTISYF 226 Query: 290 PSDKIKQLQNAIGA-----APVDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDF 344 ++ + AIGA + + Y +C + D F N + ++ + + + Sbjct: 227 TRSIVRNILYAIGAQMKFDSAGNKVYVADCKTSGTI-DFQFG-NNLKISVPVSEFLFQTY 284 Query: 345 VDGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAP 393 F ++ ILGD F+R Y V++ + ++ +AP Sbjct: 285 Y----TSGKPFPKCEVRIRESEDNILGDNFLRSAYVVYNLDDKKISMAP 329 >1J71-A nrPDB Length = 334 Score = 244 bits (623), Expect = 5e-65, Method: Composition-based stats. Identities = 94/340 (27%), Positives = 147/340 (43%), Gaps = 34/340 (10%) Query: 66 AKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWV--PSVYC-------TSPACKT 116 LIN Y I +GS Q TV+ DTGSS+LWV C T+ CK Sbjct: 3 VPTTLINE-GPSYAADIVVGSNQQKQTVVIDTGSSDLWVVDTDAECQVTYSGQTNNFCKQ 61 Query: 117 HSRFQPSQSSTYSQPGQSFSIQYGT-GSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQT 175 F PS SS+ Q FSI+YG S G D V G+++ QQF + T Sbjct: 62 EGTFDPSSSSSAQNLNQDFSIEYGDLTSSQGSFYKDTVGFGGISIKNQQFADVTTTSVD- 120 Query: 176 FVDAEFDGILGLGYPSLAVGG--VTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIF 233 GI+G+G+ + G V + Q +++ +S+Y+ N E + ++IF Sbjct: 121 ------QGIMGIGFTADEAGYNLYDNVPVTLKKQGIINKNAYSLYL--NSEDASTGKIIF 172 Query: 234 GGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDK 293 GG D++ ++G+L +PVT ++ L +I GT + S ++D+GT++ Sbjct: 173 GGVDNAKYTGTLTALPVTSSVELRVHLGSINFDGTSV--STNADVVLDSGTTITYFSQST 230 Query: 294 IKQLQNAIGAAPVDGEYAVECANLNVMPDVTFTIN-GVPYTLSPTAYTLLDFVDGMQFCS 352 + +GA + ++ D F + GV T+ + L D C Sbjct: 231 ADKFARIVGATWDSRNEIYRLPSCDLSGDAVFNFDQGVKITVPLSELILKDSDSS--ICY 288 Query: 353 SGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLA 392 G D + ILGD F+R+ Y V+D + + LA Sbjct: 289 FGISRNDAN-------ILGDNFLRRAYIVYDLDDKTISLA 321 >3FV3-A nrPDB Length = 339 Score = 244 bits (622), Expect = 6e-65, Method: Composition-based stats. Identities = 104/336 (30%), Positives = 153/336 (45%), Gaps = 42/336 (12%) Query: 77 EYFGTISIGSPPQNFTVIFDTGSSNLWV--PSVYCTSPA-CKTHSRFQPSQSSTYSQPGQ 133 Y +S+GS Q TVI DTGSS+ WV + C CK+ F PS SS+Y G Sbjct: 13 SYASKVSVGSNKQQQTVIIDTGSSDFWVVDSNAQCGKGVDCKSSGTFTPSSSSSYKNLGA 72 Query: 134 SFSIQYGTGSLS-GIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSL 192 +F+I+YG GS S G G D V++ G+++ GQQ + GILG+GY S Sbjct: 73 AFTIRYGDGSTSQGTWGKDTVTINGVSITGQQIADVTQTSVD-------QGILGIGYTSN 125 Query: 193 ------AVGGVTPVFDN----MMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFS 242 + TP +DN + Q + +S+Y+ N +IFGG D++ +S Sbjct: 126 EAVYDTSGRQTTPNYDNVPVTLKKQGKIRTNAYSLYL--NSPSAETGTIIFGGVDNAKYS 183 Query: 243 GSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIG 302 G L VT I+L ++ + G+ +G A++D+GT+L PSD QL + G Sbjct: 184 GKLVAEQVTSSQALTISLASVNLKGSSFSFGDG--ALLDSGTTLTYFPSDFAAQLADKAG 241 Query: 303 A-----APVDGEYAVECANLNVMPDVTFTI-NGVPYTLSPTAYTLLDFVDGMQFCSSGFQ 356 A A Y ++C + F NG T+ T Y +G C G Q Sbjct: 242 ARLVQVARDQYLYFIDCNT-DTSGTTVFNFGNGAKITVPNTEYVYQ---NGDGTCLWGIQ 297 Query: 357 GLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLA 392 D ILGD F+R Y +++ N + +A Sbjct: 298 PSDDT-------ILGDNFLRHAYLLYNLDANTISIA 326 >1PPK-E nrPDB Length = 323 Score = 243 bits (620), Expect = 1e-64, Method: Composition-based stats. Identities = 93/327 (28%), Positives = 143/327 (43%), Gaps = 27/327 (8%) Query: 75 DMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQS 134 D EY ++IG + FDTGS++LWV S + HS + PS + G + Sbjct: 14 DEEYITPVTIG--GTTLNLNFDTGSADLWVFSTELPASQQSGHSVYNPSATGK-ELSGYT 70 Query: 135 FSIQYGTG-SLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLA 193 +SI YG G S SG + D V+V G+T GQ + Q D DG+LGL + S+ Sbjct: 71 WSISYGDGSSASGNVFTDSVTVGGVTAHGQAVQAAQQISAQFQQDTNNDGLLGLAFSSIN 130 Query: 194 V---GGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPV 250 T FD + + + P+F+V + FG D S ++GSL + V Sbjct: 131 TVQPQSQTTFFDTVKSS--LAQPLFAVALKHQQP----GVYDFGFIDSSKYTGSLTYTGV 184 Query: 251 -TKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD-- 307 Q +W +D+ G +G I DTGT+L+ + Q + + A D Sbjct: 185 DNSQGFWSFNVDSYTAGSQ---SGDGFSGIADTGTTLLLLDDSVVSQYYSQVSGAQQDSN 241 Query: 308 -GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGP 366 G Y +C+ +PD + +I+G T+ + DG G+ + G Sbjct: 242 AGGYVFDCST--NLPDFSVSISGYTATVPGSLINYGPSGDGST----CLGGIQSNSGIG- 294 Query: 367 LWILGDVFIRQFYSVFDRGNNRVGLAP 393 I GD+F++ Y VFD ++G AP Sbjct: 295 FSIFGDIFLKSQYVVFDSDGPQLGFAP 321 >1IBQ-A nrPDB Length = 325 Score = 240 bits (612), Expect = 8e-64, Method: Composition-based stats. Identities = 97/338 (28%), Positives = 139/338 (41%), Gaps = 25/338 (7%) Query: 63 DQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQP 122 SA N D EY +++G + FDTGS++LWV S S H + P Sbjct: 2 KGSAVTTPQNN-DEEYLTPVTVG--KSTLHLDFDTGSADLWVFSDELPSSEQTGHDLYTP 58 Query: 123 SQSSTYSQPGQSFSIQYGTG-SLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEF 181 S S+T G S+ I YG G S SG + D V+V G+T Q + + D Sbjct: 59 SSSAT-KLSGYSWDISYGDGSSASGDVYRDTVTVGGVTTNKQAVEAASKISSEFVQDTAN 117 Query: 182 DGILGLGYPSLAV---GGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDH 238 DG+LGL + S+ T FD + +Q +D P+F+V + + FG D Sbjct: 118 DGLLGLAFSSINTVQPKAQTTFFDTVKSQ--LDSPLFAVQLKHDAP----GVYDFGYIDD 171 Query: 239 SHFSGSLNWVPV-TKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQL 297 S ++GS+ + + Q YW + D G S G AI DTGT+LI + + Sbjct: 172 SKYTGSITYTDADSSQGYWGFSTDG-YSIGDGSSSSSGFSAIADTGTTLILLDDEIVSAY 230 Query: 298 QNAIGAAPVD---GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSG 354 + A G Y C+ +PD T I + G C G Sbjct: 231 YEQVSGAQESYEAGGYVFSCST--DLPDFTVVIGDYKAVVPGKYINYAPVSTGSSTCYGG 288 Query: 355 FQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLA 392 Q L ILGDVF++ Y VF+ ++G A Sbjct: 289 IQ----SNSGLGLSILGDVFLKSQYVVFNSEGPKLGFA 322 >1IZE-A nrPDB Length = 323 Score = 234 bits (597), Expect = 5e-62, Method: Composition-based stats. Identities = 92/340 (27%), Positives = 140/340 (41%), Gaps = 28/340 (8%) Query: 61 SMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRF 120 + S + D EY +++G + FDTGS++LWV S S H + Sbjct: 1 AATGSVTTNPTSN-DEEYITQVTVGDD--TLGLDFDTGSADLWVFSSQTPSSERSGHDYY 57 Query: 121 QPSQSSTYSQPGQSFSIQYGTG-SLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDA 179 P SS G ++SI YG G S SG + D+V+V G++ Q + + D Sbjct: 58 TPG-SSAQKIDGATWSISYGDGSSASGDVYKDKVTVGGVSYDSQAVESAEKVSSEFTQDT 116 Query: 180 EFDGILGLGYPSLAVGGVTP---VFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGY 236 DG+LGL + S+ TP FDN+ + + P+F+V + N FG Sbjct: 117 ANDGLLGLAFSSINTVQPTPQKTFFDNVKSS--LSEPIFAVALKHNAP----GVYDFGYT 170 Query: 237 DHSHFSGSLNWVPV-TKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIK 295 D S ++GS+ + V Q +W D S+ I DTGT+L+ + Sbjct: 171 DSSKYTGSITYTDVDNSQGFWGFTADGYS--IGSDSSSDSITGIADTGTTLLLLDDSIVD 228 Query: 296 QLQNAIGAAPVD---GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCS 352 + A D G Y + +PD + TI T+ + D +G Sbjct: 229 AYYEQVNGASYDSSQGGYVFP--SSASLPDFSVTIGDYTATVPGEYISFADVGNGQT--- 283 Query: 353 SGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLA 392 F G+ + G I GDVF++ Y VFD R+G A Sbjct: 284 --FGGIQSNSGIG-FSIFGDVFLKSQYVVFDASGPRLGFA 320 >5HCT-A nrPDB Length = 419 Score = 231 bits (590), Expect = 3e-61, Method: Composition-based stats. Identities = 103/372 (27%), Positives = 152/372 (40%), Gaps = 23/372 (6%) Query: 31 SLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAKEPLINYLDMEYFGTISIGSPPQN 90 S+KK W + + SA I+ LD Y + IG+P Q Sbjct: 59 SVKKTYLKYGVPIPAWLEDAVQNSTSGLAERSTGSATTTPIDSLDDAYITPVQIGTPAQT 118 Query: 91 FTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQP-GQSF-SIQYGTGSLSGII 148 + FDTGSS+LWV S T+ + + PS+S+T G ++ S SG + Sbjct: 119 LNLDFDTGSSDLWVFSSETTASEVDGQTIYTPSKSTTAKLLSGATWSISYGDGSSSSGDV 178 Query: 149 GADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVT---PVFDNMM 205 D VSV GLTV GQ + D+ DG+LGL + +L T FDN Sbjct: 179 YTDTVSVGGLTVTGQAVESAKKVSSSFTEDSTIDGLLGLAFSTLNTVSPTQQKTFFDNAK 238 Query: 206 AQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPV-TKQAYWQIALDNIQ 264 A +D P+F+ + + FG D + ++GS+ + V TKQ +W+ Sbjct: 239 AS--LDSPVFTADLGYHAP----GTYNFGFIDTTAYTGSITYTAVSTKQGFWEWTSTGYA 292 Query: 265 VGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD---GEYAVECANLNVMP 321 VG F S I DTGT+L+ P+ + + A G Y C+ +P Sbjct: 293 VGSGT-FKSTSIDGIADTGTTLLYLPATVVSAYWAQVSGAKSSSSVGGYVFPCS--ATLP 349 Query: 322 DVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSV 381 TF + + P Y DF SS F G+ G + I GDV ++ + V Sbjct: 350 SFTFGVGSARI-VIPGDYI--DFGPISTGSSSCFGGIQSSAGIG-INIFGDVALKAAFVV 405 Query: 382 FD-RGNNRVGLA 392 F+ +G A Sbjct: 406 FNGATTPTLGFA 417 >3PI0-A nrPDB Length = 330 Score = 219 bits (559), Expect = 1e-57, Method: Composition-based stats. Identities = 99/339 (29%), Positives = 145/339 (42%), Gaps = 23/339 (6%) Query: 64 QSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPS 123 SA I+ LD Y + IG+P Q + FDTGSS+LWV S T+ + + PS Sbjct: 3 GSATTTPIDSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVDGQTIYTPS 62 Query: 124 QSSTYSQP-GQSF-SIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEF 181 +S+T G ++ S SG + D VSV GLTV GQ + D+ Sbjct: 63 KSTTAKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTGQAVESAKKVSSSFTEDSTI 122 Query: 182 DGILGLGYPSLAVGGVT---PVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDH 238 DG+LGL + +L T FDN A +D P+F+ + + FG D Sbjct: 123 DGLLGLAFSTLNTVSPTQQKTFFDNAKAS--LDSPVFTADLGYHAP----GTYNFGFIDT 176 Query: 239 SHFSGSLNWVPV-TKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQL 297 + ++GS+ + V TKQ +W+ VG F S I DTGT+L+ P+ + Sbjct: 177 TAYTGSITYTAVSTKQGFWEWTSTGYAVGSGT-FKSTSIDGIADTGTTLLYLPATVVSAY 235 Query: 298 QNAIGAAPVD---GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSG 354 + A G Y C+ +P TF + + P Y DF SS Sbjct: 236 WAQVSGAKSSSSVGGYVFPCS--ATLPSFTFGVGSARI-VIPGDYI--DFGPISTGSSSC 290 Query: 355 FQGLDIHPPAGPLWILGDVFIRQFYSVFD-RGNNRVGLA 392 F G+ G + I GDV ++ + VF+ +G A Sbjct: 291 FGGIQSSAGIG-INIFGDVALKAAFVVFNGATTPTLGFA 328 >3EMY-A nrPDB Length = 329 Score = 215 bits (547), Expect = 4e-56, Method: Composition-based stats. Identities = 86/337 (25%), Positives = 136/337 (40%), Gaps = 20/337 (5%) Query: 64 QSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQP- 122 SA + D EY ++SIG+P Q + FDTGSS+LWV S + H+ + P Sbjct: 3 GSAPNHPSDSADSEYITSVSIGTPAQVLPLDFDTGSSDLWVFSSETPKSSATGHAIYTPS 62 Query: 123 SQSSTYSQPGQSF-SIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEF 181 S++ G S+ S SG + D+V++ G +V Q + + D Sbjct: 63 KSSTSKKVSGASWSISYGDGSSSSGDVYTDKVTIGGFSVNTQGVESATRVSTEFVQDTVI 122 Query: 182 DGILGLGYPSLAVGGVTP--VFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHS 239 G++GL + S P + + A +L P+F+ + FG D S Sbjct: 123 SGLVGLAFDSGNQVRPHPQKTWFSNAASSL-AEPLFTADLRHGQN----GSYNFGYIDTS 177 Query: 240 HFSGSLNWVPV-TKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQ 298 G + + PV Q +W+ VGG + I DTGT+L+ + + Sbjct: 178 VAKGPVAYTPVDNSQGFWEFTASGYSVGGGKLN-RNSIDGIADTGTTLLLLDDNVVDAYY 236 Query: 299 NAIGAAPVDGE---YAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGF 355 + +A D + +C +P +F + T+ L +G C F Sbjct: 237 ANVQSAQYDNQQEGVVFDCD--EDLPSFSFGVGSSTITIPGDLLNLTPLEEGSSTC---F 291 Query: 356 QGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLA 392 GL G + I GDV ++ VFD GN R+G A Sbjct: 292 GGLQSSSGIG-INIFGDVALKAALVVFDLGNERLGWA 327 >3OAD-B nrPDB Length = 176 Score = 213 bits (542), Expect = 1e-55, Method: Composition-based stats. Identities = 63/169 (37%), Positives = 97/169 (57%) Query: 226 GAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTS 285 G +++ GG D H+ G+ +++ + K WQI + + VG + + C +GC A+VDTG S Sbjct: 1 SLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGAS 60 Query: 286 LITGPSDKIKQLQNAIGAAPVDGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFV 345 I+G + I++L A+GA +Y V+C +PD++F + G YTL+ Y + Sbjct: 61 YISGSTSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESY 120 Query: 346 DGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPA 394 + C+ +DI PP GP W LG FIR+FY+ FDR NNR+G A A Sbjct: 121 SSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALA 169 >3O9L-A nrPDB Length = 166 Score = 205 bits (521), Expect = 4e-53, Method: Composition-based stats. Identities = 70/163 (42%), Positives = 105/163 (64%), Gaps = 3/163 (1%) Query: 63 DQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTS--PACKTHSRF 120 + ++ L NY+D +Y+G I IG+PPQ F V+FDTGSSN+WVPS C+ AC H F Sbjct: 5 NTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLF 64 Query: 121 QPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAE 180 S SS+Y G +++Y TG++SG + D ++V G+TV Q FGE P F+ AE Sbjct: 65 DASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVT-QMFGEVTEMPALPFMLAE 123 Query: 181 FDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNP 223 FDG++G+G+ A+G VTP+FDN+++Q ++ +FS Y + + Sbjct: 124 FDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDS 166 >1WKR-A nrPDB Length = 340 Score = 204 bits (520), Expect = 5e-53, Method: Composition-based stats. Identities = 102/346 (29%), Positives = 154/346 (44%), Gaps = 39/346 (11%) Query: 66 AKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQS 125 P N L ++Y + +GSP ++++ DTGSSN W+ + ++ Sbjct: 3 GSVPATNQL-VDYVVNVGVGSPATTYSLLVDTGSSNTWLGADKSYV------------KT 49 Query: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGIL 185 ST S S+ YG+GS SG D V++ LT+ Q G + + G V DGIL Sbjct: 50 STSSATSDKVSVTYGSGSFSGTEYTDTVTLGSLTIPKQSIGVASRDSGFDGV----DGIL 105 Query: 186 GLGYPSLAVGGVTP--------VFDNMMAQNLVDLPMFSV-YMSSNPEGGAGSELIFGGY 236 G+G L VG ++P V DN+ +Q + + +V + + E EL FG Sbjct: 106 GVGPVDLTVGTLSPHTSTSIPTVTDNLFSQGTIPTNLLAVSFEPTTSESSTNGELTFGAT 165 Query: 237 DHSHFSGSLNWVPVTK----QAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSD 292 D S ++GS+ + P+T AYW I +I+ G + S IVDTGT+L SD Sbjct: 166 DSSKYTGSITYTPITSTSPASAYWGIN-QSIRYGSSTSILS-STAGIVDTGTTLTLIASD 223 Query: 293 KIKQLQNAIGAAPVD--GEYAVECANLNVMPDVTFTINGVPYTLSPTA----YTLLDFVD 346 + + A GA + G + A + + FTI G + L+ A L + Sbjct: 224 AFAKYKKATGAVADNNTGLLRLTTAQYANLQSLFFTIGGQTFELTANAQIWPRNLNTAIG 283 Query: 347 GMQFCSSGFQG-LDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGL 391 G G L G +I G F+ +FYSV+D N R+GL Sbjct: 284 GSASSVYLIVGDLGSDSGEGLDFINGLTFLERFYSVYDTTNKRLGL 329 >4ZL4-A nrPDB Length = 444 Score = 186 bits (472), Expect = 2e-47, Method: Composition-based stats. Identities = 100/443 (22%), Positives = 152/443 (34%), Gaps = 122/443 (27%) Query: 57 TESCSMDQSAKEPLINYLD--MEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPAC 114 TE S D K L +D YF I IG+P Q ++I DTGSS+L P C + Sbjct: 7 TEGHSKDLLYKYKLYGDIDEYAYYFLDIDIGTPEQRISLILDTGSSSLSFPCAGCKNCGV 66 Query: 115 KTHSRFQPSQSSTYSQP---------------GQSFSIQ-YGTGS-LSGIIGADQVSV-- 155 + F + S T S G+ +Q Y GS +SG +D VSV Sbjct: 67 HMENPFNLNNSKTSSILYCENEECPFKLNCVKGKCEYMQSYCEGSQISGFYFSDVVSVVS 126 Query: 156 -EGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVD-LP 213 V ++ F+ + G+LG+ SL+ P F N++ N Sbjct: 127 YNNERVTFRKLMGCHMHEESLFLYQQATGVLGM---SLSKPQGIPTFVNLLFDNAPQLKQ 183 Query: 214 MFSVYMSSNPEGGAGSELIFGGYDHSHF-------------SGSLN-------------- 246 +F++ +S N G ELI GGYD ++ SG ++ Sbjct: 184 VFTICISEN-----GGELIAGGYDPAYIVRRGGSKSVSGQGSGPVSESLSESGEDPQVAL 238 Query: 247 -------WVPVTKQAYWQIALDNIQVGGT-VMFCSEGCQAIVDTGTSLITGPSDKIKQLQ 298 W VT++ Y+ I + + + GT +M S+G + +VD+G++ P D +L Sbjct: 239 REAEKVVWENVTRKYYYYIKVRGLDMFGTNMMSSSKGLEMLVDSGSTFTHIPEDLYNKLN 298 Query: 299 ------------------------------------------NAIGAAPVDGEYAVE--- 313 +I A V+ Sbjct: 299 YFFDILCIQDMNNAYDVNKRLKMTNESFNNPLVQFDDFRKSLKSIIAKENMCVKIVDGVQ 358 Query: 314 CANL-NVMPDVTFTI-NGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILG 371 C +PD+ T+ N P +Y F I ILG Sbjct: 359 CWKYLEGLPDLFVTLSNNYKMKWQPHSYLYKKE---------SFWCKGIEKQVNNKPILG 409 Query: 372 DVFIRQFYSVFDRGNNRVGLAPA 394 F + +FD NR+G A Sbjct: 410 LTFFKNRQVIFDIQKNRIGFVDA 432 >4OD9-A nrPDB Length = 103 Score = 140 bits (352), Expect = 1e-33, Method: Composition-based stats. Identities = 51/98 (52%), Positives = 65/98 (66%), Gaps = 2/98 (2%) Query: 60 CSMDQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCT--SPACKTH 117 + E L NY+D +Y+G I IG+PPQ FTV+FDTGSSNLWVPS++C AC H Sbjct: 2 AVTEGPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIH 61 Query: 118 SRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSV 155 ++ +SSTY + G SF I YG+GSLSG + D VSV Sbjct: 62 HKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSV 99 >1B5F-B nrPDB Length = 87 Score = 107 bits (266), Expect = 1e-23, Method: Composition-based stats. Identities = 39/84 (46%), Positives = 50/84 (59%), Gaps = 1/84 (1%) Query: 312 VECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILG 371 V+C L+ MP+V+FTI G + L+P Y L C SGF +D GPLWILG Sbjct: 5 VDCNTLSSMPNVSFTIGGKKFGLTPEQYILKVGKGEATQCISGFTAMD-ATLLGPLWILG 63 Query: 372 DVFIRQFYSVFDRGNNRVGLAPAV 395 DVF+R +++VFD GN VG A A Sbjct: 64 DVFMRPYHTVFDYGNLLVGFAEAA 87 >3AUP-A nrPDB Length = 403 Score = 55.4 bits (132), Expect = 5e-08, Method: Composition-based stats. Identities = 61/367 (16%), Positives = 112/367 (30%), Gaps = 76/367 (20%) Query: 86 SPPQNFTVIFDTGSSNLWVPSVY-----------CTSPACKTHSRFQ----PSQSSTYSQ 130 +P V+ D ++LWV C S C + Q P+ S Sbjct: 31 TPLMQVPVLVDLNGNHLWVNCEQQYSSKTYQAPFCHSTQCSRANTHQCLSCPAASRPGCH 90 Query: 131 PGQSFSIQ---YGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTF----------- 176 + + G +G D +++ QQ G VT P F Sbjct: 91 KNTCGLMSTNPITQQTGLGELGEDVLAIHATQGSTQQLGPLVTVPQFLFSCAPSFLVQKG 150 Query: 177 VDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGG- 235 + G+ GLG+ +++ + Q F+ +S P + +IFG Sbjct: 151 LPRNTQGVAGLGHAPISLPNQLASHFGLQRQ-------FTTCLSRYP--TSKGAIIFGDA 201 Query: 236 ------YDHSHFSGSLNWVP--VTKQAYWQIALDNIQVG----------GTVMFCSEGCQ 277 + + L + P +T Q + + +++I++ + + S Sbjct: 202 PNNMRQFQNQDIFHDLAFTPLTITLQGEYNVRVNSIRINQHSVFPLNKISSTIVGSTSGG 261 Query: 278 AIVDTGTSLITGPSDKIKQL----------QNAIGAAPVDGEYAVECANLNVMPDVTFTI 327 ++ T T + + Q + + G +N P V + Sbjct: 262 TMISTSTPHMVLQQSVYQAFTQVFAQQLPKQAQVKSVAPFGLC-FNSNKINAYPSVDLVM 320 Query: 328 ---NGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDR 384 NG + +S + C G + P A LG + + VFD Sbjct: 321 DKPNGPVWRISGEDLMVQ--AQPGVTC-LGVMNGGMQPRAEIT--LGARQLEENLVVFDL 375 Query: 385 GNNRVGL 391 +RVG Sbjct: 376 ARSRVGF 382 >4PPH-A nrPDB Length = 417 Score = 54.3 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 60/375 (16%), Positives = 110/375 (29%), Gaps = 83/375 (22%) Query: 86 SPPQNFTVIFDTGSSNLWVPSVY-----------CTSPACK---THSRFQPSQSSTYS-- 129 +P ++ D +LWV C S C TH F + S+T Sbjct: 36 TPLMQVPLLLDLNGKHLWVTCSQHYSSSTYQAPFCHSTQCSRANTHQCFTCTDSTTTRPG 95 Query: 130 -QPGQSFSIQY---GTGSLSGIIGADQVSVEG---------LTVVGQQFGESVTEPGQTF 176 + S G + D +++ + V F + + Q Sbjct: 96 CHNNTCGLLSSNPVTQESGLGELAQDVLAIHSTHGSKLGPMVKVPQFLFSCAPSFLAQKG 155 Query: 177 VDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGY 236 + G LGLG +++ + Q FSV +S + ++FG Sbjct: 156 LPNNVQGALGLGQAPISLQNQLFSHFGLKRQ-------FSVCLSRYS--TSNGAILFGDI 206 Query: 237 D----HSHFSGSL------NWVPVT--KQAYWQIALDNIQVGGTVMFCSEGC-------- 276 + +++ SL + P+T KQ + I ++ I+V ++ ++ Sbjct: 207 NDPNNNNYIHNSLDVLHDLVYTPLTISKQGEYFIQVNAIRVNKHLVIPTKNPFISPSSTS 266 Query: 277 --------QAIVDTGTSLITGPSDKIKQL----------QNAIGAAPVDGEYAVECANLN 318 A++ T + Q + A G Sbjct: 267 YHGSGEIGGALITTTHPYTVLSHSIFEVFTQVFANNMPKQAQVKAVGPFGLCYDSRKISG 326 Query: 319 VMP--DVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILGDVFIR 376 P D+ N + +S + + S +D A LG + Sbjct: 327 GAPSVDLILDKNDAVWRISSENFMVQAQDG-----VSCLGFVDGGVHARAGIALGAHHLE 381 Query: 377 QFYSVFDRGNNRVGL 391 + VFD +RVG Sbjct: 382 ENLVVFDLERSRVGF 396 >1T6G-A nrPDB Length = 381 Score = 46.9 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 56/324 (17%), Positives = 96/324 (29%), Gaps = 53/324 (16%) Query: 105 PSVYCTSPACKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQ 164 P+ C +P+C + +P + Y S GSLS + V Sbjct: 62 PAPGCPAPSCGSDKHDKPCTAYPY----NPVSGACAAGSLSHTRFVANTTDGSKPVSKVN 117 Query: 165 FGESVTEPGQTFVDAE---FDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSS 221 G + + G+ GL LA+ AQ + F + + + Sbjct: 118 VGVLAACAPSKLLASLPRGSTGVAGLANSGLALPAQV-----ASAQKV--ANRFLLCLPT 170 Query: 222 NPEGGAGSELIFGG--YDHSHFSGSLNWVPVTKQA---YWQIALDNIQVGGTVMFCSEGC 276 IFGG F+ S+ + P+ + I+ +I VG T + EG Sbjct: 171 GGP----GVAIFGGGPVPWPQFTQSMPYTPLVTKGGSPAHYISARSIVVGDTRVPVPEGA 226 Query: 277 QA----------------------IVDTGTSLITGPSDKIKQLQNAIGAAPVDGEYAVEC 314 A ++D T + + A+ A G + Sbjct: 227 LATGGVMLSTRLPYVLLRPDVYRPLMDAFTKALAAQHANGAPVARAVEAVAPFGVC-YDT 285 Query: 315 ANLNV------MPDVTFTI-NGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPL 367 L +P+V + G +T++ + +G+ P Sbjct: 286 KTLGNNLGGYAVPNVQLGLDGGSDWTMTGKNSMVDVKQGTACVAFVEMKGVAAGDGRAPA 345 Query: 368 WILGDVFIRQFYSVFDRGNNRVGL 391 ILG + F FD R+G Sbjct: 346 VILGGAQMEDFVLDFDMEKKRLGF 369 >3HD8-A nrPDB Length = 389 Score = 44.6 bits (104), Expect = 8e-05, Method: Composition-based stats. Identities = 60/333 (18%), Positives = 106/333 (31%), Gaps = 71/333 (21%) Query: 105 PSVYCTSPACKTHSR------FQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGL 158 P+ C +P+C + + + + G F ++ + G +V+V Sbjct: 64 PAPGCPAPSCGSDRHDKPCTAYPSNPVTGACAAGSLFHTRFAANTTDGNKPVSEVNV--- 120 Query: 159 TVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVY 218 + + G+ GL LA+ AQ + + F + Sbjct: 121 ----RVLAACAPSKLLASLPRGSTGVAGLAGSGLALPSQV-----ASAQKVPNK--FLLC 169 Query: 219 MSSNPEGGAGSELIFGG--YDHSHFSGSLNWVPVTKQA---YWQIALDNIQVGGTVMFCS 273 + + IFGG F+ S+++ P+ + I+ +I+V T + S Sbjct: 170 LPTGGP----GVAIFGGGPLPWPQFTQSMDYTPLVAKGGSPAHYISARSIKVENTRVPIS 225 Query: 274 EGCQAIVDTGTSLIT--GP---------SDKIKQLQNAIGAAPVDGEYAVECANLNVMPD 322 E A TG +++ P + A+ A P +G V P Sbjct: 226 ERALA---TGGVMLSTRLPYVLLRRDVYRPLVDAFTKALAAQPANGAPV----ARAVKPV 278 Query: 323 VTFTINGVPYTLS--PTAY----TLLDFVDGMQFCSSG------------------FQGL 358 F + TL P Y LL+ G + +G +G+ Sbjct: 279 APFELCYDTKTLGNNPGGYWVPNVLLELDGGSDWAMTGKNSMVDVKPGTACVAFVEMKGV 338 Query: 359 DIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGL 391 D + P ILG + F FD R+G Sbjct: 339 DAGDGSAPAVILGGAQMEDFVLDFDMEKKRLGF 371 >3OS6-A nrPDB Length = 399 Score = 32.3 bits (72), Expect = 0.40, Method: Composition-based stats. Identities = 8/46 (17%), Positives = 17/46 (36%) Query: 237 DHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDT 282 D F+G L W + W + + +V + G + ++ Sbjct: 324 DREFFTGMLGWSDLNGDGEWIVTIRCAEVQENTLRLYAGAGVVAES 369 >2BKL-A nrPDB Length = 695 Score = 31.5 bits (70), Expect = 0.69, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 14/31 (45%) Query: 73 YLDMEYFGTISIGSPPQNFTVIFDTGSSNLW 103 LD Y+ S +P Q + TG S LW Sbjct: 373 DLDDAYYVFTSFTTPRQIYKTSVSTGKSELW 403 >3Q31-A nrPDB Length = 244 Score = 30.8 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 19/89 (21%), Positives = 33/89 (37%), Gaps = 15/89 (16%) Query: 175 TFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFG 234 A+ ++G + VG P+FD++ A +D + +L FG Sbjct: 119 FQTAAKETAVVGFFFQLSEVGDSVPLFDSVFA--PIDN------IPDAGTSTTTGQLDFG 170 Query: 235 GYDHSH-------FSGSLNWVPVTKQAYW 256 G ++GSL P T++ W Sbjct: 171 GLLDHFNRHGVYQYTGSLTTPPCTEEVMW 199 >1LPA-B nrPDB Length = 449 Score = 28.8 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 22/78 (28%), Gaps = 1/78 (1%) Query: 109 CTSPACKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGII-GADQVSVEGLTVVGQQFGE 167 C S C + + GQ F + G S V++ G V G Sbjct: 300 CPSGGCPQMGHYADRYPGKTNDVGQKFYLDTGDASNFARWRYKVSVTLSGKKVTGHILVS 359 Query: 168 SVTEPGQTFVDAEFDGIL 185 G + F G L Sbjct: 360 LFGNKGNSKQYEIFKGTL 377 >3NJX-A nrPDB Length = 508 Score = 28.8 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 28/138 (20%), Positives = 48/138 (34%), Gaps = 7/138 (5%) Query: 47 KSHNLDMIQFTESCSMDQSAKEPLINYLDME-YFGTISIGSPPQNFTVIFDTGSSNLWVP 105 H + F+ S + S LD++ Y G + SS WV Sbjct: 219 GLHGPYSMYFSRSGTPSTSIDTSFFADLDIKGYVAASGRGKVAGTAS---GADSSMDWVV 275 Query: 106 SVYCTSPACKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQF 165 Y + T++ S +S +PG +++ Y G + + V+V + + Sbjct: 276 HWYNDAAQYWTYTSSSGSFTSPAMKPGT-YTMVYYQGEYA--VATSSVTVSAGSTTTKNI 332 Query: 166 GESVTEPGQTFVDAEFDG 183 SV F E+DG Sbjct: 333 SGSVKTGTTIFKIGEWDG 350 >1IGA-A nrPDB Length = 475 Score = 28.4 bits (62), Expect = 5.0, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 18/44 (40%), Gaps = 3/44 (6%) Query: 87 PPQNFTVIFDTGSSNLWVPSVYC---TSPACKTHSRFQPSQSST 127 P Q+ + T SS L +P+ C S C PSQ T Sbjct: 177 PSQDASGDLYTTSSQLTLPATQCLAGKSVTCHVKHYTNPSQDVT 220 >3TBJ-A nrPDB Length = 237 Score = 28.4 bits (62), Expect = 5.2, Method: Composition-based stats. Identities = 16/96 (16%), Positives = 31/96 (32%), Gaps = 3/96 (3%) Query: 76 MEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYSQPGQSF 135 +Y+ +G Q +F T S + T T+ + G Sbjct: 128 TDYYAQEEVGDFFQQVVDLFKTLDSYTALSDAGITPSEDATYKLSDIEDALAAIHDGYPP 187 Query: 136 SIQYGTGSLSGIIGADQV---SVEGLTVVGQQFGES 168 + G+LS + V ++ G V ++ +S Sbjct: 188 YVGCEDGALSQLYYYFNVKGSAIGGTYVASERLEDS 223 >1FR5-A nrPDB Length = 125 Score = 27.7 bits (60), Expect = 9.1, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 21/59 (35%), Gaps = 8/59 (13%) Query: 278 AIVDTGTS--LITGPSDKIKQLQNAIGAAPVDGEYAVECANLNVMPDVTFTINGVPYTL 334 +VD G + + PS+ + I + Y V C+ + N YT+ Sbjct: 8 VLVDNGGTGDVKVAPSNFANGVAEWISSNSRSQAYKVTCSVRQS------SANNRKYTV 60 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.138 0.391 Lambda K H 0.267 0.0422 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,251,147 Number of Sequences: 36641 Number of extensions: 687479 Number of successful extensions: 2390 Number of sequences better than 10.0: 80 Number of HSP's better than 10.0 without gapping: 128 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 1740 Number of HSP's gapped (non-prelim): 172 length of query: 396 length of database: 10,336,785 effective HSP length: 99 effective length of query: 297 effective length of database: 6,709,326 effective search space: 1992669822 effective search space used: 1992669822 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.7 bits)