BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P14061 (328 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6CGE-A nrPDB 660 0.0 1A27-A nrPDB 584 e-167 3RKU-A nrPDB 84 9e-17 5OVL-A nrPDB 80 1e-15 1GEG-A nrPDB 80 1e-15 3U9L-A nrPDB 80 2e-15 5OVJ-A nrPDB 80 2e-15 1UZM-A nrPDB 79 4e-15 4NBV-A nrPDB 76 2e-14 2ZAT-A nrPDB 76 2e-14 3OEC-A nrPDB 73 1e-13 3WYE-A nrPDB 73 1e-13 4JRO-A nrPDB 73 2e-13 3O4R-A nrPDB 71 8e-13 2NM0-A nrPDB 70 1e-12 3UVE-A nrPDB 70 1e-12 4DBZ-A nrPDB 69 4e-12 6CI9-A nrPDB 68 5e-12 5EJ2-A nrPDB 67 8e-12 3V2H-A nrPDB 67 1e-11 5B1Y-A nrPDB 65 3e-11 5ITV-A nrPDB 64 6e-11 3LYL-A nrPDB 64 7e-11 3WOH-A nrPDB 64 9e-11 3RSH-A nrPDB 64 1e-10 1NFF-A nrPDB 64 1e-10 3WTC-A nrPDB 62 3e-10 1Q7C-A nrPDB 62 3e-10 3A28-C nrPDB 62 3e-10 3OSU-A nrPDB 62 4e-10 1K2W-A nrPDB 61 7e-10 2CFC-A nrPDB 60 1e-09 3GRP-A nrPDB 60 1e-09 4DMM-A nrPDB 60 1e-09 2EW8-A nrPDB 60 2e-09 3U5T-A nrPDB 60 2e-09 5CDY-A nrPDB 60 2e-09 4K6F-A nrPDB 59 3e-09 3W8F-A nrPDB 59 3e-09 3EMK-A nrPDB 58 4e-09 4RGB-A nrPDB 58 5e-09 3T7C-A nrPDB 58 5e-09 2GDZ-A nrPDB 58 7e-09 4BO1-A nrPDB 57 7e-09 4E6P-A nrPDB 57 8e-09 2HSD-A nrPDB 57 1e-08 1X1T-A nrPDB 57 1e-08 3EZL-A nrPDB 57 1e-08 4FC7-A nrPDB 57 1e-08 5YSS-A nrPDB 57 1e-08 4M8S-A nrPDB 56 2e-08 5VT6-A nrPDB 56 2e-08 3OIC-A nrPDB 56 2e-08 3AUT-A nrPDB 56 2e-08 4NBT-A nrPDB 56 3e-08 5O3Z-A nrPDB 55 4e-08 3VZS-A nrPDB 55 4e-08 3OML-A nrPDB 55 5e-08 2NWQ-A nrPDB 55 5e-08 3V8B-A nrPDB 55 6e-08 3E9N-A nrPDB 55 6e-08 3UF0-A nrPDB 54 7e-08 1AE1-A nrPDB 54 8e-08 2UVD-A nrPDB 54 1e-07 4IS3-A nrPDB 54 1e-07 3UN1-A nrPDB 54 1e-07 3V2G-A nrPDB 54 1e-07 4MOW-A nrPDB 53 2e-07 1GEE-A nrPDB 53 2e-07 4RZH-A nrPDB 53 2e-07 3F9I-A nrPDB 53 2e-07 3FTP-A nrPDB 52 3e-07 4IIV-A nrPDB 52 3e-07 3RWB-A nrPDB 52 3e-07 2PH3-A nrPDB 52 3e-07 5U9P-A nrPDB 52 3e-07 3PXX-A nrPDB 52 3e-07 1O5I-A nrPDB 52 5e-07 4TRR-A nrPDB 51 7e-07 2Q2Q-A nrPDB 51 8e-07 2HQ1-A nrPDB 50 9e-07 4RZI-B nrPDB 50 1e-06 2PNF-A nrPDB 50 1e-06 3D3W-A nrPDB 50 2e-06 2AG5-A nrPDB 50 2e-06 2CDH-G nrPDB 49 2e-06 6NRP-A nrPDB 49 3e-06 1CYD-A nrPDB 48 5e-06 4CQM-B nrPDB 48 6e-06 1SNY-A nrPDB 48 8e-06 2AE2-A nrPDB 47 1e-05 2O23-A nrPDB 47 1e-05 4HP8-A nrPDB 46 2e-05 5PGZ-A nrPDB 46 2e-05 2B4Q-A nrPDB 46 2e-05 4CQL-A nrPDB 46 3e-05 3DWF-A nrPDB 45 3e-05 2C07-A nrPDB 45 4e-05 1YXM-A nrPDB 45 5e-05 2FWM-X nrPDB 44 8e-05 3ZV3-A nrPDB 44 8e-05 5IZ4-A nrPDB 44 1e-04 1H5Q-A nrPDB 43 2e-04 1BDB-A nrPDB 43 2e-04 4KMS-A nrPDB 43 2e-04 4Z9Y-A nrPDB 42 3e-04 4DRY-A nrPDB 42 4e-04 2HRB-A nrPDB 41 6e-04 1E3W-A nrPDB 40 0.002 1W73-A nrPDB 39 0.002 5OJG-A nrPDB 39 0.003 3R3S-A nrPDB 39 0.003 5JY1-A nrPDB 37 0.010 3KZV-A nrPDB 37 0.012 5L51-A nrPDB 37 0.015 4OYR-A nrPDB 36 0.020 1DOH-A nrPDB 36 0.020 5WQO-A nrPDB 35 0.031 4AVY-A nrPDB 35 0.033 1FJH-A nrPDB 35 0.034 2P91-A nrPDB 35 0.047 5LCX-A nrPDB 35 0.048 4GKB-A nrPDB 35 0.053 3GRK-A nrPDB 33 0.16 4DA9-A nrPDB 33 0.19 2NTV-A nrPDB 33 0.19 1AHH-A nrPDB 33 0.19 1HXH-A nrPDB 33 0.22 5TF4-A nrPDB 33 0.22 5KOI-A nrPDB 33 0.22 1MG5-A nrPDB 33 0.22 4HBG-A nrPDB 32 0.28 1B15-A nrPDB 32 0.41 3O26-A nrPDB 31 0.57 2YW9-A nrPDB 30 1.1 3NUT-A nrPDB 30 1.6 2DKN-A nrPDB 30 1.7 4IIN-A nrPDB 30 2.1 4MWA-D nrPDB 29 2.6 1NL7-A nrPDB 29 2.6 2PD3-A nrPDB 29 3.1 5ORE-A nrPDB 28 4.2 4TLZ-A nrPDB 28 6.1 2YNM-C nrPDB 27 9.7 >6CGE-A nrPDB Length = 328 Score = 660 bits (1702), Expect = 0.0, Method: Compositional matrix adjust. Identities = 328/328 (100%), Positives = 328/328 (100%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL Sbjct: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 Query: 61 ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV Sbjct: 61 ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 Query: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH Sbjct: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180 Query: 181 LSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV 240 LSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV Sbjct: 181 LSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV 240 Query: 241 FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFGDVPAKAEAGAEAGG 300 FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFGDVPAKAEAGAEAGG Sbjct: 241 FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFGDVPAKAEAGAEAGG 300 Query: 301 GAGPGAEDEAGRGAVGDPELGDPPAAPQ 328 GAGPGAEDEAGRGAVGDPELGDPPAAPQ Sbjct: 301 GAGPGAEDEAGRGAVGDPELGDPPAAPQ 328 >1A27-A nrPDB Length = 289 Score = 584 bits (1506), Expect = e-167, Method: Compositional matrix adjust. Identities = 289/289 (100%), Positives = 289/289 (100%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE Sbjct: 1 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 60 Query: 62 TLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 TLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR Sbjct: 61 TLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 120 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL Sbjct: 121 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 180 Query: 182 SLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVF 241 SLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVF Sbjct: 181 SLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVF 240 Query: 242 LTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFGDVPA 290 LTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFGDVPA Sbjct: 241 LTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFGDVPA 289 >3RKU-A nrPDB Length = 287 Score = 84.0 bits (206), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 62/205 (30%), Positives = 95/205 (46%), Gaps = 22/205 (10%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARAL--ACPPG 58 +A+ VLITG S+GIG A+ + K+ R L+ +L E + + P Sbjct: 31 LAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLE---KLEELKKTIDQEFPNA 87 Query: 59 SLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVAS------ 110 + QLD+ ++ + E + + +D+LV NAG +ALG D V Sbjct: 88 KVHVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAG-------KALGSDRVGQIATEDI 140 Query: 111 --VLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCE 168 V D NV + + QA LP + + SG ++ GS+ G P +YCASKFA+ + Sbjct: 141 QDVFDTNVTALINITQAVLPIFQAKNSGDIVNLGSIAGRDAYPTGSIYCASKFAVGAFTD 200 Query: 169 SLAVLLLPFGVHLSLIECGPVHTAF 193 SL L+ + + LI G V T F Sbjct: 201 SLRKELINTKIRVILIAPGLVETEF 225 >5OVL-A nrPDB Length = 300 Score = 80.1 bits (196), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 63/188 (33%), Positives = 92/188 (48%), Gaps = 19/188 (10%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 VL+TG + GIGL +A RLA+D KV T R + P L +Q Sbjct: 71 VLVTGGNRGIGLAIARRLAAD---GHKVAVTHRG--------------SGAPDDLFGVQC 113 Query: 66 DVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRML 123 DV DS +V A + V E G V+VLV NAG+ L + E+ V++ N+ G R Sbjct: 114 DVTDSAAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCA 173 Query: 124 QAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSL 183 Q M+R+ GR++ GSV G+ G+ Y A+K L G+ S++ L GV ++ Sbjct: 174 QRASRTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANV 233 Query: 184 IECGPVHT 191 + G + T Sbjct: 234 VAPGYIDT 241 >1GEG-A nrPDB Length = 256 Score = 80.1 bits (196), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 65/199 (32%), Positives = 99/199 (49%), Gaps = 11/199 (5%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKV-YATLRDLKTQGRLWEAARALACPPGSLE 61 + V L+TG GIG +A+RL D F V A D + E +A G Sbjct: 2 KKVALVTGAGQGIGKAIALRLVKD---GFAVAIADYNDATAKAVASEINQA----GGHAV 54 Query: 62 TLQLDVRDSKSVAAARE--RVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGT 119 +++DV D V AA E R T G DV+V NAG+ P+E++ + V V ++NV G Sbjct: 55 AVKVDVSDRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGV 114 Query: 120 VRMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 + +QA + K+ G G+++ S G +G P VY +SKFA+ GL ++ A L P G Sbjct: 115 IWGIQAAVEAFKKEGHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLG 174 Query: 179 VHLSLIECGPVHTAFMEKV 197 + ++ G V T ++ Sbjct: 175 ITVNGYCPGIVKTPMWAEI 193 >3U9L-A nrPDB Length = 324 Score = 79.7 bits (195), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 54/145 (37%), Positives = 82/145 (56%), Gaps = 11/145 (7%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALAC----P 56 M++ ++LITG SSG G A LA +VYA++RD+ GR A+A Sbjct: 3 MSKKIILITGASSGFGRLTAEALAG---AGHRVYASMRDIV--GRNASNVEAIAGFARDN 57 Query: 57 PGSLETLQLDVRDSKSVAAARERVT--EGRVDVLVCNAGLGLLGPLEALGEDAVASVLDV 114 L TL+LDV+ SV A +++ +GR+DVL+ NAG + GP EA + A + D+ Sbjct: 58 DVDLRTLELDVQSQVSVDRAIDQIIGEDGRIDVLIHNAGHMVFGPAEAFTPEQFAELYDI 117 Query: 115 NVVGTVRMLQAFLPDMKRRGSGRVL 139 NV+ T R+ +A LP M+R+ G ++ Sbjct: 118 NVLSTQRVNRAALPHMRRQKHGLLI 142 >5OVJ-A nrPDB Length = 256 Score = 79.7 bits (195), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 63/188 (33%), Positives = 92/188 (48%), Gaps = 19/188 (10%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 VL+TG + GIGL +A RLA+D KV T R + P L +Q Sbjct: 27 VLVTGGNRGIGLAIARRLAAD---GHKVAVTHRG--------------SGAPDDLFGVQC 69 Query: 66 DVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRML 123 DV DS +V A + V E G V+VLV NAG+ L + E+ V++ N+ G R Sbjct: 70 DVTDSAAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCA 129 Query: 124 QAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSL 183 Q M+R+ GR++ GSV G+ G+ Y A+K L G+ S++ L GV ++ Sbjct: 130 QRASRTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANV 189 Query: 184 IECGPVHT 191 + G + T Sbjct: 190 VAPGYIDT 197 >1UZM-A nrPDB Length = 247 Score = 78.6 bits (192), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 64/188 (34%), Positives = 91/188 (48%), Gaps = 19/188 (10%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 VL+TG + GIGL +A RLA+D KV T R + P L +++ Sbjct: 18 VLVTGGNRGIGLAIAQRLAAD---GHKVAVTHRG--------------SGAPKGLFGVEV 60 Query: 66 DVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRML 123 DV DS +V A V E G V+VLV NAGL L + E+ V++ N+ G R+ Sbjct: 61 DVTDSDAVDRAFTAVEEHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVA 120 Query: 124 QAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSL 183 Q M+R GR++ GSV GL G+ Y ASK + G+ S+A L V ++ Sbjct: 121 QRASRSMQRNKFGRMIFIGSVSGLWGIGNQANYAASKAGVIGMARSIARELSKANVTANV 180 Query: 184 IECGPVHT 191 + G + T Sbjct: 181 VAPGYIDT 188 >4NBV-A nrPDB Length = 246 Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 69/204 (33%), Positives = 100/204 (49%), Gaps = 11/204 (5%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 V +ITG ++GIG A R A D + L D++ + R+ EAA LA ++ + Sbjct: 7 VAIITGAAAGIGFATAQRFAEDGA-----IVVLCDVQ-EARVREAAARLAATGATVSAYR 60 Query: 65 LDV--RDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 +DV RD A RVD+LV NAG+ L + E +V+DVN+ G Sbjct: 61 VDVTRRDEVDAMVAAVLAAHQRVDILVNNAGITKDARLAKMTEAQFDAVIDVNLKGVFNC 120 Query: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLS 182 QA M +G G +L SV GL G Y ASKF + G ++ A L P GV ++ Sbjct: 121 AQAVAGLMTEQGKGVILNASSVVGLYGNFGQTNYAASKFGVIGFTKTWARELGPKGVRVN 180 Query: 183 LIECGPVHTAFMEKVLGSPEEVLD 206 + G V+T ++ V P++VLD Sbjct: 181 AVCPGFVNTEILQTV---PDKVLD 201 >2ZAT-A nrPDB Length = 260 Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 65/203 (32%), Positives = 95/203 (46%), Gaps = 19/203 (9%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSF-------KVYATLRDLKTQGRLWEAARAL 53 + V L+T + GIGL +A RLA D + V T+ L+ +G + Sbjct: 12 LENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGL---SVTGT 68 Query: 54 ACPPGSLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLG-LLGPLEALGEDAVASVL 112 C G E + + VA A G VD+LV NA + G + E+ +L Sbjct: 69 VCHVGKAEDRE------RLVAMAVN--LHGGVDILVSNAAVNPFFGNIIDATEEVWDKIL 120 Query: 113 DVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAV 172 VNV TV M +A +P+M++RG G VL+ SVG P Y SK AL GL ++LAV Sbjct: 121 HVNVKATVLMTKAVVPEMEKRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAV 180 Query: 173 LLLPFGVHLSLIECGPVHTAFME 195 L P + ++ + G + T F + Sbjct: 181 ELAPRNIRVNCLAPGLIKTNFSQ 203 >3OEC-A nrPDB Length = 317 Score = 73.2 bits (178), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 70/218 (32%), Positives = 100/218 (45%), Gaps = 37/218 (16%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKV----------YA---------TLRDLKTQGR 45 V ITG + G G AVRLA D + + YA T+R ++ QGR Sbjct: 48 VAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKETVRLVEEQGR 107 Query: 46 LWEAARALACPPGSLETLQLDVRDSKSV-AAARERVTE-GRVDVLVCNAGLGLLGPLEAL 103 R +A Q DVRD S+ A E + E G +D+LV N G+ G + +L Sbjct: 108 -----RIIA--------RQADVRDLASLQAVVDEALAEFGHIDILVSNVGISNQGEVVSL 154 Query: 104 GEDAVASVLDVNVVGTVRMLQAFLPDMKRRGS-GRVLVTGSVGGLMGLPFNDVYCASKFA 162 + + +L N++G +A LP M RG G V+ S GL G P Y ASK Sbjct: 155 TDQQWSDILQTNLIGAWHACRAVLPSMIERGQGGSVIFVSSTVGLRGAPGQSHYAASKHG 214 Query: 163 LEGLCESLAVLLLPFGVHLSLIECGPVHT--AFMEKVL 198 ++GL SLA + + ++ + G V+T A EK+L Sbjct: 215 VQGLMLSLANEVGRHNIRVNSVNPGAVNTEMALNEKLL 252 >3WYE-A nrPDB Length = 256 Score = 73.2 bits (178), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 62/199 (31%), Positives = 95/199 (47%), Gaps = 11/199 (5%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKV-YATLRDLKTQGRLWEAARALACPPGSLE 61 + V L+TG GIG +A+RL D F V A D + E +A G Sbjct: 2 KKVALVTGAGQGIGKAIALRLVKD---GFAVAIADYNDATAKAVASEINQA----GGHAV 54 Query: 62 TLQLDVRDSKSVAAARE--RVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGT 119 +++DV D V AA E R T G DV+V NAG+ + PL + E+ + + VNV Sbjct: 55 AVKVDVSDRDQVFAAVEQARKTLGGFDVIVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSV 114 Query: 120 VRMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 +QA + K+ G G+++ S+ + G P Y +KFA+ GL ++ A L P G Sbjct: 115 FFGIQAAVEAFKKEGHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAARDLAPLG 174 Query: 179 VHLSLIECGPVHTAFMEKV 197 + ++ G V T E++ Sbjct: 175 ITVNGYCPGIVGTGMWEQI 193 >4JRO-A nrPDB Length = 271 Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 58/203 (28%), Positives = 103/203 (50%), Gaps = 7/203 (3%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 V ++TG S GIG +A+ LA + + F Y + E A+ +A +E ++ Sbjct: 31 VAVVTGGSRGIGRDIAINLAKEGANIFFNYNGSPEAAE-----ETAKLVAEHGVEVEAMK 85 Query: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 +V ++ V A ++ E GRVD+LV NAG+ L + ED V+++N+ GT Sbjct: 86 ANVAIAEDVDAFFKQAIERFGRVDILVNNAGITRDNLLMRMKEDEWDDVININLKGTFLC 145 Query: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLS 182 +A M ++ +G+++ SV GL+G Y ASK + GL ++ A L P G++++ Sbjct: 146 TKAVSRTMMKQRAGKIINMASVVGLIGNAGQANYVASKAGVIGLTKTTARELAPRGINVN 205 Query: 183 LIECGPVHTAFMEKVLGSPEEVL 205 + G + T +K+ +E + Sbjct: 206 AVAPGFITTDMTDKLDEKTKEAM 228 >3O4R-A nrPDB Length = 261 Score = 70.9 bits (172), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 56/201 (27%), Positives = 93/201 (46%), Gaps = 19/201 (9%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASD-------PSQSFKVYATLRDLKTQGRLWEAARAL 53 +A V L+T + GIG +A RLA D + V + L+ +G + Sbjct: 13 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGL---SVTGT 69 Query: 54 ACPPGSLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLG-LLGPLEALGEDAVASVL 112 C G E D + + A ++ G +D+LV NA + G + + E+ L Sbjct: 70 VCHVGKAE-------DRERLVATAVKL-HGGIDILVSNAAVNPFFGSIMDVTEEVWDKTL 121 Query: 113 DVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAV 172 D+NV M +A +P+M++RG G V++ S+ P Y SK AL GL ++LA+ Sbjct: 122 DINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAI 181 Query: 173 LLLPFGVHLSLIECGPVHTAF 193 L P + ++ + G + T+F Sbjct: 182 ELAPRNIRVNCLAPGLIKTSF 202 >2NM0-A nrPDB Length = 253 Score = 70.1 bits (170), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 66/200 (33%), Positives = 97/200 (48%), Gaps = 21/200 (10%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 M+R+V L+TG + GIGL +A R +D KV T R PP Sbjct: 20 MSRSV-LVTGGNRGIGLAIA-RAFADAGD--KVAITYRS--------------GEPPEGF 61 Query: 61 ETLQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 ++ D+ D++ V A + + T G V+VL+ NAG+ L + E+ SV++ N+ G Sbjct: 62 LAVKCDITDTEQVEQAYKEIEETHGPVEVLIANAGVTKDQLLMRMSEEDFTSVVETNLTG 121 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 T R+++ M R GRV++ SV GL+G Y ASK L G SLA L Sbjct: 122 TFRVVKRANRAMLRAKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARSLARELGSRN 181 Query: 179 VHLSLIECGPVHTAFMEKVL 198 + +++ G V T M KVL Sbjct: 182 ITFNVVAPGFVDTD-MTKVL 200 >3UVE-A nrPDB Length = 286 Score = 70.1 bits (170), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 62/200 (31%), Positives = 94/200 (47%), Gaps = 19/200 (9%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKV----------YATLRDLKTQGRLWEAARALA 54 V +TG + G G AVRLA + + V T T L E A + Sbjct: 13 VAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDLAETADLVK 72 Query: 55 CPPGSLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLG-PLEALGEDAVASV 111 + T ++DVRD ++ AA + E GR+D++V NAG+G G L+ E+ + Sbjct: 73 GHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNGGDTLDKTSEEDWTEM 132 Query: 112 LDVNVVGTVRMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170 +D+N+ G + ++A +P M G G +++T SVGGL P Y A+K + GL + Sbjct: 133 IDINLAGVWKTVKAGVPHMIAGGRGGSIILTSSVGGLKAYPHTGHYVAAKHGVVGLMRAF 192 Query: 171 AVLLLPFGVHLSLIECGPVH 190 V L G H +I VH Sbjct: 193 GVEL---GQH--MIRVNSVH 207 >4DBZ-A nrPDB Length = 281 Score = 68.6 bits (166), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 71/247 (28%), Positives = 106/247 (42%), Gaps = 30/247 (12%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSF-------KVYATLRDLKTQGRLWEAARALACPP 57 V L+TG +SGIGL +A RL + + F + TL++L+ G A C Sbjct: 28 VALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGV---EADGRTC-- 82 Query: 58 GSLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVN 115 DVR + A V E G VDVLV NAG G L ++ V++ N Sbjct: 83 --------DVRSVPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELADELWLDVVETN 134 Query: 116 VVGTVRMLQAFLP--DMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVL 173 + G R+ + L M RG+GR++ S GG GL Y ASK + G ++L + Sbjct: 135 LTGVFRVTKQVLKAGGMLERGTGRIVNIASTGGKQGLVHAAPYSASKHGVVGFTKALGLE 194 Query: 174 LLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQN 233 L G+ ++ + G V T V ++ + + F R + + V Sbjct: 195 LARTGITVNAVCPGFVETPMAASVREHYSDIWEVSTEEAFDRITARVPIGRYV------Q 248 Query: 234 PEEVAEV 240 P EVAE+ Sbjct: 249 PSEVAEM 255 >6CI9-A nrPDB Length = 259 Score = 68.2 bits (165), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 63/197 (31%), Positives = 95/197 (48%), Gaps = 15/197 (7%) Query: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLD 66 ++TG S GIG +A A+ V T R+ Q L L+ G + ++ D Sbjct: 13 IVTGGSKGIGRGIAETFAN---AGVDVVITGRN---QDDLDRTVADLSGTRGKVTAVRAD 66 Query: 67 VRDSKSVAAARERVTE-----GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 V D + AR V E G +D++ NAG+ G LE L D + VL VN GTV Sbjct: 67 VTDPED---ARRTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKGTVY 123 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGG-LMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180 ++QA L + G GRV+VT S+ G + G P Y ASK A G + A+ L P + Sbjct: 124 IVQAALQALTASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAMELAPKKIT 183 Query: 181 LSLIECGPVHTAFMEKV 197 ++ + G + T ++++ Sbjct: 184 INAVLPGNIMTEGLDEM 200 >5EJ2-A nrPDB Length = 308 Score = 67.4 bits (163), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 58/204 (28%), Positives = 101/204 (49%), Gaps = 10/204 (4%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQ--SFKVYATLRDL----KTQGRLWEAARALA 54 +A V I+G + G G AVRLA + + + + + +L T L E A + Sbjct: 35 VAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETADLVK 94 Query: 55 CPPGSLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLG-PLEALGEDAVASV 111 + T Q+DVRD +++ +A + E GR+D++V NAG+G G L + ++ + Sbjct: 95 DLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTDGRKLHKIRDNVWQDM 154 Query: 112 LDVNVVGTVRMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170 +D+N+ G ++A +P + G G +++T SVGG P Y A+K + GL + Sbjct: 155 IDINLTGVWHTVKAGVPHVLSGGRGGSIVLTSSVGGRKAYPNTGHYIAAKHGVIGLMRAF 214 Query: 171 AVLLLPFGVHLSLIECGPVHTAFM 194 AV L P + ++ + V T + Sbjct: 215 AVELGPHMIRVNAVLPTQVSTTMV 238 >3V2H-A nrPDB Length = 281 Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 57/200 (28%), Positives = 96/200 (48%), Gaps = 11/200 (5%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQ----SFKVYATLRDLKTQGRLWEAARALACP 56 M +T V ITG +SGIGL +A LA + F +R + + + L P Sbjct: 24 MTKTAV-ITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAGLSSGTVLHHP 82 Query: 57 PGSLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNV 116 T ++ D ++ A R G D+LV NAG+ + +E + ++ VN+ Sbjct: 83 ADM--TKPSEIADMMAMVADRF----GGADILVNNAGVQFVEKIEDFPVEQWDRIIAVNL 136 Query: 117 VGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLP 176 + ++ +P MK++G GR++ S GL+ PF Y A+K + GL +++A+ + Sbjct: 137 SSSFHTIRGAIPPMKKKGWGRIINIASAHGLVASPFKSAYVAAKHGIMGLTKTVALEVAE 196 Query: 177 FGVHLSLIECGPVHTAFMEK 196 GV ++ I G V T +EK Sbjct: 197 SGVTVNSICPGYVLTPLVEK 216 >5B1Y-A nrPDB Length = 270 Score = 65.5 bits (158), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 72/245 (29%), Positives = 104/245 (42%), Gaps = 22/245 (8%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 M T L+TG S GIG +R A + Y + DL + E AR L P Sbjct: 21 METTYALVTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTA--EEARRLGSPEAY- 77 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 T+++DV D SV RV E ++VLV AG+ LG +E L VN+ G Sbjct: 78 -TVRVDVGDPDSVTEMSSRVGELIPHLNVLVNAAGVLQLGGIEETSISEWEETLRVNLTG 136 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDV-YCASKFALEGLCESLAVLLLPF 177 + + LP +++ ++ S+ G G V Y ASK + GL + LAV L + Sbjct: 137 VYLVTKLLLPLLRKAKWASIVNVASIAGETGNVVAGVAYSASKAGVIGLTKRLAVQLAGY 196 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV 237 G+ ++ + V T L +PE+ R I + H L PE+V Sbjct: 197 GIRVNAVAPSFVETDMTRSFLDTPEK---RERIASLHPLKIIL------------KPEDV 241 Query: 238 AEVFL 242 AE L Sbjct: 242 AEAIL 246 >5ITV-A nrPDB Length = 255 Score = 64.3 bits (155), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 69/245 (28%), Positives = 112/245 (45%), Gaps = 31/245 (12%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 VLITG +SGIG + AV+ A Q+ V A + + + + + + L +Q Sbjct: 10 VLITGGASGIG-YAAVQ-AFLGQQANVVVADIDEAQGEAMVRKENN------DRLHFVQT 61 Query: 66 DVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRML 123 D+ D + A E T G +DVL+ NAG+ ++ P+ + VL VN+ G M Sbjct: 62 DITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMS 121 Query: 124 QAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSL 183 + L M G G ++ T SVGGL+ P Y ASK + L +S+AV + ++ Sbjct: 122 KHALKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIRVNC 181 Query: 184 IECGPVHT-----AFMEKVLGSPEEV-LDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV 237 + G + T +F+E G+ EE+ ++ ++ R + PEE+ Sbjct: 182 VCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRLGK---------------PEEI 226 Query: 238 AEVFL 242 A V L Sbjct: 227 ANVML 231 >3LYL-A nrPDB Length = 247 Score = 64.3 bits (155), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 54/200 (27%), Positives = 91/200 (45%), Gaps = 18/200 (9%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATL-------RDLKTQGRLWEAARALACPP 57 V L+TG S GIG +A LAS + + +K +G AR L Sbjct: 7 VALVTGASRGIGFEVAHALASKGATVVGTATSQASAEKFENSMKEKGF---KARGLVLNI 63 Query: 58 GSLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVV 117 +E++Q + K+ A +D+LV NAG+ + + ED SV++ N+ Sbjct: 64 SDIESIQNFFAEIKAENLA--------IDILVNNAGITRDNLMMRMSEDEWQSVINTNLS 115 Query: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 RM + + M ++ GR++ GSV G G P YCA+K + G +SLA + Sbjct: 116 SIFRMSKECVRGMMKKRWGRIISIGSVVGSAGNPGQTNYCAAKAGVIGFSKSLAYEVASR 175 Query: 178 GVHLSLIECGPVHTAFMEKV 197 + ++++ G + T +K+ Sbjct: 176 NITVNVVAPGFIATDMTDKL 195 >3WOH-A nrPDB Length = 251 Score = 63.9 bits (154), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 63/218 (28%), Positives = 102/218 (46%), Gaps = 18/218 (8%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRD--LKTQG---RLWEAARALACPPGS 59 V L+TG S G+G +A+RLA D + VY + +TQG RL AR+ C Sbjct: 13 VALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLGGTARSYRC---- 68 Query: 60 LETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVV 117 DV D++ V + VT G VD+LV NAG+ G ++ ++ +V++ N+ Sbjct: 69 ------DVSDAEQVTRCVKAVTADLGPVDILVNNAGIIRDGLAASIKDEDYDAVMNTNLK 122 Query: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 G ++A R+ SG ++ SV G+ G Y ++K L GL +S+A L Sbjct: 123 GAFLFIKACYFGFIRKRSGSIINISSVSGVFGSAGQANYASAKAGLIGLTKSIAKELAER 182 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHR 215 V + + G + T + ++ + LD + F R Sbjct: 183 NVRCNAVAPGLIATDMTQDLVDDSKR-LDPVPMRRFGR 219 >3RSH-A nrPDB Length = 251 Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 55/190 (28%), Positives = 95/190 (50%), Gaps = 13/190 (6%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPG-SLETL 63 V L+TG S GIG +A LA + KV T A+A++ G + + + Sbjct: 14 VALVTGASRGIGKAIAELLAE---RGAKVIGTATS-------ESGAQAISDYLGDNGKGM 63 Query: 64 QLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 L+V + +S+ A + +T+ G VD+LV NAG+ L + E+ + +++ N+ R Sbjct: 64 ALNVTNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFR 123 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 + +A L M ++ GR++ GSV G MG Y A+K + G +S+A + GV + Sbjct: 124 LSKAVLRGMMKKRQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVASRGVTV 183 Query: 182 SLIECGPVHT 191 + + G + T Sbjct: 184 NTVAPGFIET 193 >1NFF-A nrPDB Length = 260 Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 47/145 (32%), Positives = 71/145 (48%), Gaps = 5/145 (3%) Query: 63 LQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 + LDV AA + G + VLV NAG+ +G +E +LDVN+ G Sbjct: 58 VHLDVTQPAQWKAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLTGVF 117 Query: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180 ++A + MK G G ++ S+ GL G Y A+KFA+ GL +S A+ L P G+ Sbjct: 118 LGIRAVVKPMKEAGRGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTALELGPSGIR 177 Query: 181 LSLIECGPVHTAFMEKVLGSPEEVL 205 ++ I G V T + V PE++ Sbjct: 178 VNSIHPGLVKTPMTDWV---PEDIF 199 >3WTC-A nrPDB Length = 262 Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 58/220 (26%), Positives = 99/220 (45%), Gaps = 9/220 (4%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 + +TG + GIG +A+RLA D + L D+K Q L E A+ + L Sbjct: 10 IAAVTGAAQGIGKAIALRLAKDGADVI-----LLDVK-QDTLAETAKEVEALGRRAVALT 63 Query: 65 LDV--RDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 D+ RD A T G +D++V NAG+ + P+ + + + +NV G + Sbjct: 64 ADISNRDQFRSTLADAAKTLGGLDIMVNNAGICQVKPILDIEPAEIEKIFSINVQGVLWG 123 Query: 123 LQAFLPDMKRRGS-GRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 +QA K +G+ G+++ S+ G G P Y A+KFA+ L +S A L G+ + Sbjct: 124 MQAAATLFKEKGTKGKIINACSIAGHEGYPLLGAYSATKFAVRALTQSAAKELASSGITV 183 Query: 182 SLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLA 221 + G V T + E+ T+ ++ + +A Sbjct: 184 NSYCPGIVGTDMWVTIDKRMAEITGTEIGATYKKYVEGIA 223 >1Q7C-A nrPDB Length = 244 Score = 62.0 bits (149), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 53/190 (27%), Positives = 94/190 (49%), Gaps = 13/190 (6%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL-ETL 63 + L+TG S GIG +A LA+ + KV T A+A++ G+ + L Sbjct: 7 IALVTGASRGIGRAIAETLAA---RGAKVIGTATS-------ENGAQAISDYLGANGKGL 56 Query: 64 QLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 L+V D S+ + E++ G VD+LV NAG+ L + ++ +++ N+ R Sbjct: 57 MLNVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFR 116 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 + +A + M ++ GR++ GSV G MG + A+K L G +SLA + G+ + Sbjct: 117 LSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANFAAAKAGLIGFSKSLAREVASRGITV 176 Query: 182 SLIECGPVHT 191 +++ G + T Sbjct: 177 NVVAPGFIET 186 >3A28-C nrPDB Length = 258 Score = 62.0 bits (149), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 59/205 (28%), Positives = 92/205 (44%), Gaps = 25/205 (12%) Query: 5 VVLITGCSSGIGLHLAVRLASD---------PSQSFKVYATLRDLKTQGRLWEAARALAC 55 V ++TG + GIG ++ +LA+D P Q + T++ L EAA A Sbjct: 4 VAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQEEQAAETIK-------LIEAADQKAV 56 Query: 56 PPGSLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLD 113 G LDV D + +A + E G DVLV NAG+ + PL + E+ + + Sbjct: 57 FVG------LDVTDKANFDSAIDEAAEKLGGFDVLVNNAGIAQIKPLLEVTEEDLKQIYS 110 Query: 114 VNVVGTVRMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAV 172 VNV +QA G G+++ S+ + G P Y +KFA+ GL ++ A Sbjct: 111 VNVFSVFFGIQAASRKFDELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQ 170 Query: 173 LLLPFGVHLSLIECGPVHTAFMEKV 197 L P G ++ G V T E++ Sbjct: 171 ELAPKGHTVNAYAPGIVGTGMWEQI 195 >3OSU-A nrPDB Length = 246 Score = 61.6 bits (148), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 57/183 (31%), Positives = 91/183 (49%), Gaps = 7/183 (3%) Query: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLD 66 L+TG S GIG +A++LA + YA ++ K + + E +A ++ Q + Sbjct: 8 LVTGASRGIGRSIALQLAEEGYNVAVNYAGSKE-KAEA-VVEEIKAKGVDSFAI---QAN 62 Query: 67 VRDSKSVAAA-RERVTE-GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQ 124 V D+ V A +E V++ G +DVLV NAG+ L + E V+D N+ G +Q Sbjct: 63 VADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQ 122 Query: 125 AFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLI 184 P M R+ SG ++ SV G +G P Y A+K + GL +S A L G+ ++ + Sbjct: 123 KATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAV 182 Query: 185 ECG 187 G Sbjct: 183 APG 185 >1K2W-A nrPDB Length = 256 Score = 60.8 bits (146), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 56/187 (29%), Positives = 89/187 (47%), Gaps = 14/187 (7%) Query: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPG-SLETLQL 65 LITG + GIG A + ++ + D+ EAARA A G + + L Sbjct: 9 LITGSARGIGRAFAEAYVREGAR-----VAIADINL-----EAARATAAEIGPAACAIAL 58 Query: 66 DVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRML 123 DV D S+ + + G +D+LV NA L L P+ + ++ + +NV GT+ M+ Sbjct: 59 DVTDQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGTLFMM 118 Query: 124 QAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLS 182 QA M G G+++ S G G VYCA+K A+ L +S + L+ G++++ Sbjct: 119 QAVARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNLIRHGINVN 178 Query: 183 LIECGPV 189 I G V Sbjct: 179 AIAPGVV 185 >2CFC-A nrPDB Length = 250 Score = 60.1 bits (144), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 65/216 (30%), Positives = 96/216 (44%), Gaps = 16/216 (7%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRL-WEAARALACPPGS 59 M+R V ++TG SSG GL +A R + + + + L+ R W A Sbjct: 1 MSR-VAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHA------YADK 53 Query: 60 LETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGL---GLLGPLEALGEDAVASVLDV 114 + ++ DV D V AA E G +DVLV NAG+ G L + V+ V Sbjct: 54 VLRVRADVADEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAV 113 Query: 115 NVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLL 174 NV G +A LP M +G+G ++ SV L+ P Y SK A+ L +S+AV Sbjct: 114 NVRGIFLGCRAVLPHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDY 173 Query: 175 LPFGVHLSLIECGPVHTAFMEKVLGSPE---EVLDR 207 G+ + + G + T + L PE +VL R Sbjct: 174 AGSGIRCNAVCPGMIETPMTQWRLDQPELRDQVLAR 209 >3GRP-A nrPDB Length = 266 Score = 60.1 bits (144), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 54/199 (27%), Positives = 89/199 (44%), Gaps = 7/199 (3%) Query: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLD 66 L+TG + GIG +A R ++ T D +L E A L D Sbjct: 31 LVTGATGGIGEAIA-RCFHAQGAIVGLHGTRED-----KLKEIAADLGKDVFVFSANLSD 84 Query: 67 VRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAF 126 + K +A ER EG +D+LV NAG+ G + + VL VN+ + + Sbjct: 85 RKSIKQLAEVAEREMEG-IDILVNNAGITRDGLFVRMQDQDWDDVLAVNLTAASTLTREL 143 Query: 127 LPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIEC 186 + M RR GR++ S+ G++G P YCA+K L G ++LA + + ++ I Sbjct: 144 IHSMMRRRYGRIINITSIVGVVGNPGQTNYCAAKAGLIGFSKALAQEIASRNITVNCIAP 203 Query: 187 GPVHTAFMEKVLGSPEEVL 205 G + +A +K+ +E + Sbjct: 204 GFIKSAMTDKLNEKQKEAI 222 >4DMM-A nrPDB Length = 269 Score = 60.1 bits (144), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 61/189 (32%), Positives = 93/189 (49%), Gaps = 7/189 (3%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 + L+TG S GIG +A+ LA+ ++ YA+ + G E A+A G ++ Sbjct: 30 IALVTGASRGIGRAIALELAAAGAKVAVNYAS-----SAGAADEVVAAIAAAGGEAFAVK 84 Query: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 DV V A V E GR+DVLV NAG+ L + D SVLD+N+ G Sbjct: 85 ADVSQESEVEALFAAVIERWGRLDVLVNNAGITRDTLLLRMKRDDWQSVLDLNLGGVFLC 144 Query: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLS 182 +A M ++ SGR++ SV G MG P Y A+K + GL +++A L G+ ++ Sbjct: 145 SRAAAKIMLKQRSGRIINIASVVGEMGNPGQANYSAAKAGVIGLTKTVAKELASRGITVN 204 Query: 183 LIECGPVHT 191 + G + T Sbjct: 205 AVAPGFIAT 213 >2EW8-A nrPDB Length = 249 Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 58/191 (30%), Positives = 88/191 (46%), Gaps = 10/191 (5%) Query: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLD 66 +ITG ++GIG +A R A + + + DL A R L + T++ D Sbjct: 11 VITGGANGIGRAIAERFAVEGAD-----IAIADLVPAPEAEAAIRNLG---RRVLTVKCD 62 Query: 67 VRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQ 124 V V A ++V T GR D+LV NAG+ L P + L + ++NV M + Sbjct: 63 VSQPGDVEAFGKQVISTFGRCDILVNNAGIYPLIPFDELTFEQWKKTFEINVDSGFLMAK 122 Query: 125 AFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLI 184 AF+P MKR G GR++ S + + Y ++K A G +LA L G+ ++ I Sbjct: 123 AFVPGMKRNGWGRIINLTSTTYWLKIEAYTHYISTKAANIGFTRALASDLGKDGITVNAI 182 Query: 185 ECGPVHTAFME 195 V TA E Sbjct: 183 APSLVRTATTE 193 >3U5T-A nrPDB Length = 267 Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 66/208 (31%), Positives = 91/208 (43%), Gaps = 17/208 (8%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 V ++TG S GIG +A RLASD YA E A + G T Q Sbjct: 29 VAIVTGASRGIGAAIAARLASDGFTVVINYA-----GKAAAAEEVAGKIEAAGGKALTAQ 83 Query: 65 LDVRDSKSV----AAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 DV D +V A A E G VDVLV NAG+ L + G+ V+ VN+ GT Sbjct: 84 ADVSDPAAVRRLFATAEEAF--GGVDVLVNNAGIMPLTTIAETGDAVFDRVIAVNLKGTF 141 Query: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180 L+ ++ G + T VG L P +Y A+K +E + L+ L + Sbjct: 142 NTLREAAQRLRVGGRIINMSTSQVGLLH--PSYGIYAAAKAGVEAMTHVLSKELRGRDIT 199 Query: 181 LSLIECGPVHT-AFMEKVLGSPEEVLDR 207 ++ + GP T F+E G +EV DR Sbjct: 200 VNAVAPGPTATDLFLE---GKSDEVRDR 224 >5CDY-A nrPDB Length = 244 Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 55/189 (29%), Positives = 87/189 (46%), Gaps = 11/189 (5%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 + L+TG S GIG +A L A + T + EA A G + L Sbjct: 7 IALVTGASRGIGRAIAELLVERG-------ACVIGTATSEKGAEAISAYLGENG--KGLM 57 Query: 65 LDVRDSKSVAA--ARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 L+V D S+ A R G VD+LV NAG+ L + +D ++D N+ R+ Sbjct: 58 LNVVDPTSIDTVLATIRAEFGEVDILVNNAGITRDNLLMRMKDDEWQDIIDTNLTSVFRL 117 Query: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLS 182 +A + M ++ GR++ GSV G MG Y A+K + G +SLA + G+ ++ Sbjct: 118 SKAVMRAMMKKRFGRIITIGSVVGTMGNAGQVNYAAAKAGVIGFSKSLAREVASRGITVN 177 Query: 183 LIECGPVHT 191 ++ G + T Sbjct: 178 VVAPGFIET 186 >4K6F-A nrPDB Length = 255 Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 55/213 (25%), Positives = 90/213 (42%), Gaps = 20/213 (9%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLW-----EAARALAC 55 M + + ++TG G+G +++RL +V T T W A R Sbjct: 9 MTKRIAVVTGGMGGLGEAVSIRL---NDAGHRVVVTYSPNNTGADRWLTEMHAAGREFHA 65 Query: 56 PPGSLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLD 113 P +DV D S E++ G VD+LV NAG+ L L + +V+ Sbjct: 66 YP-------VDVADHDSCQQCIEKIVRDVGPVDILVNNAGITRDMTLRKLDKVNWDAVIR 118 Query: 114 VNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVL 173 N+ M + M RG GR++ SV G G Y A+K + G +SLA+ Sbjct: 119 TNLDSVFNMTKPVCDGMVERGWGRIVNISSVNGSKGSVGQTNYAAAKAGMHGFTKSLALE 178 Query: 174 LLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLD 206 + GV ++ + G + T + + P+++LD Sbjct: 179 IARKGVTVNTVSPGYLATKMVTAI---PQDILD 208 >3W8F-A nrPDB Length = 260 Score = 58.5 bits (140), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 52/195 (26%), Positives = 91/195 (46%), Gaps = 12/195 (6%) Query: 7 LITGCSSGIGLHLAVRLASDPSQS-FKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 ++TG +SGIGL +A LA + + D++ + E+ + L Sbjct: 8 VVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVKA-----YYLNA 62 Query: 66 DVRDSKS----VAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 D+ D+++ +A A E + G +D+LV NAG+ P+E D +++ +N+ Sbjct: 63 DLSDAQATRDFIAKAAEAL--GGLDILVNNAGIQHTAPIEEFPVDKWNAIIALNLSAVFH 120 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 A LP M+++G GR++ S GL+ Y A+K + GL + A+ G+ Sbjct: 121 GTAAALPIMQKQGWGRIINIASAHGLVASVNKSAYVAAKHGVVGLTKVTALENAGKGITC 180 Query: 182 SLIECGPVHTAFMEK 196 + I G V T +EK Sbjct: 181 NAICPGWVRTPLVEK 195 >3EMK-A nrPDB Length = 246 Score = 58.2 bits (139), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 41/134 (30%), Positives = 68/134 (50%), Gaps = 2/134 (1%) Query: 66 DVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRML 123 ++ D ++V A ++ E G VD+LV NAG+ G + ++ +VL VN+ + Sbjct: 61 NLSDREAVKALGQKAEEEMGGVDILVNNAGITRDGLFVRMSDEDWDAVLTVNLTSVFNLT 120 Query: 124 QAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSL 183 + M RR +GR++ S+ G+ G P YCASK L G +SLA + V ++ Sbjct: 121 RELTHPMMRRRNGRIINITSIVGVTGNPGQANYCASKAGLIGFSKSLAQEIASRNVTVNC 180 Query: 184 IECGPVHTAFMEKV 197 I G + +A K+ Sbjct: 181 IAPGFIESAMTGKL 194 >4RGB-A nrPDB Length = 294 Score = 58.2 bits (139), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 54/183 (29%), Positives = 79/183 (43%), Gaps = 13/183 (7%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSF------KVYATLRDLKTQGRLWEAARALACPPG 58 VV ITG + G G AV A + + L T L E AR + Sbjct: 27 VVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEETARLVEKTGQ 86 Query: 59 SLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNV 116 + + DVRD + + E G +D ++ NAG+ L P E +A+ LD+ + Sbjct: 87 EMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLTNPDERDASEALRLGLDIML 146 Query: 117 VGTVRMLQAFLPDMKRRGS-GRVLVTGSVGGLMGLPF----NDVYCASKFALEGLCESLA 171 +G Q +P MK RG G ++ T S+ L+ L D Y SK A+ GL S A Sbjct: 147 IGVWNTFQVAIPHMKERGQGGNLIATSSMIALLDLTDGRGGTDAYLTSKLAITGLVRSYA 206 Query: 172 VLL 174 ++L Sbjct: 207 LML 209 >3T7C-A nrPDB Length = 299 Score = 58.2 bits (139), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 62/218 (28%), Positives = 100/218 (45%), Gaps = 13/218 (5%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQ--SFKVYATLRDLK----TQGRLWEAARALACPPG 58 V ITG + G G A+ LA + + + V L +K T L E R + Sbjct: 30 VAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETVRQVEALGR 89 Query: 59 SLETLQLDVRDSKSV-AAARERVTE-GRVDVLVCNAGLGLLGP-LEALGEDAVASVLDVN 115 + Q+DVRD ++ AA + VT+ GR+D+++ NA L G L + ++DVN Sbjct: 90 RIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRMDPKTWRDMIDVN 149 Query: 116 VVGTVRMLQAFLPD-MKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLL 174 + G + +P M + G ++ T S+GGL G Y ASK L GL ++A+ L Sbjct: 150 LNGAWITARVAIPHIMAGKRGGSIVFTSSIGGLRGAENIGNYIASKHGLHGLMRTMALEL 209 Query: 175 LPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHT 212 P + ++++ V T + L P + R D+ Sbjct: 210 GPRNIRVNIVCPSSVATPML---LNEPTYRMFRPDLEN 244 >2GDZ-A nrPDB Length = 267 Score = 57.8 bits (138), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 64/231 (27%), Positives = 97/231 (41%), Gaps = 29/231 (12%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 V L+TG + GIG A L ++ V L G +AA P +Q Sbjct: 9 VALVTGAAQGIGRAFAEALLLKGAKVALVDWNLE----AGVQCKAALHEQFEPQKTLFIQ 64 Query: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 DV D + + +V + GR+D+LV NAG+ E L +N+V + Sbjct: 65 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVISG 116 Query: 123 LQAFLPDMKRRGSGR---VLVTGSVGGLMGLPFNDVYCASKFALEGLCES--LAVLLLPF 177 L M ++ G ++ S+ GLM + VYCASK + G S LA L+ Sbjct: 117 TYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNS 176 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFR 228 GV L+ I G V+TA +E + EE ++ +Y H K + + Sbjct: 177 GVRLNAICPGFVNTAILESI--EKEE--------NMGQYIEYKDHIKDMIK 217 >4BO1-A nrPDB Length = 269 Score = 57.4 bits (137), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 54/179 (30%), Positives = 81/179 (45%), Gaps = 28/179 (15%) Query: 5 VVLITGCSSGIGLHLAVRL----------ASDPSQSFKVYATLRDLKTQGRLWEAARALA 54 V L+TG S GIG +A+ L A+ S + K+ TL+ +G Sbjct: 29 VALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEG---------- 78 Query: 55 CPPGSLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVL 112 L LDV +SVAA E + + G+ ++V NAG+ L + +D V+ Sbjct: 79 ------AGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEWFDVV 132 Query: 113 DVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLA 171 + N+ R+ +A L M + GR++ GSV G MG Y A+K LEG +LA Sbjct: 133 NTNLNSLYRLSKAVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALA 191 >4E6P-A nrPDB Length = 259 Score = 57.4 bits (137), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 54/187 (28%), Positives = 86/187 (45%), Gaps = 14/187 (7%) Query: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPG-SLETLQL 65 LITG + GIG A + + + D+ E AR A G + +Q+ Sbjct: 12 LITGSARGIGRAFAEAYVREGAT-----VAIADIDI-----ERARQAAAEIGPAAYAVQM 61 Query: 66 DVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRML 123 DV S+ AA E G +D+LV NA L L P+ + ++ + +NV GT+ L Sbjct: 62 DVTRQDSIDAAIAATVEHAGGLDILVNNAALFDLAPIVEITRESYEKLFAINVAGTLFTL 121 Query: 124 QAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLS 182 QA M +G G+++ S G G +YCA+K A+ L +S + L+ ++++ Sbjct: 122 QAAARQMIAQGRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAGLDLIKHRINVN 181 Query: 183 LIECGPV 189 I G V Sbjct: 182 AIAPGVV 188 >2HSD-A nrPDB Length = 253 Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 40/121 (33%), Positives = 60/121 (49%), Gaps = 2/121 (1%) Query: 71 KSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDM 130 + VA ARE G VD LV NAG+ LE + V+++N+ G ++ +P M Sbjct: 68 RVVAYAREEF--GSVDGLVNNAGISTGMFLETESVERFRKVVEINLTGVFIGMKTVIPAM 125 Query: 131 KRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVH 190 K G G ++ S GLMGL Y ASK+ + GL + AV L + ++ + G + Sbjct: 126 KDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVHPGMTY 185 Query: 191 T 191 T Sbjct: 186 T 186 >1X1T-A nrPDB Length = 260 Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 55/204 (26%), Positives = 87/204 (42%), Gaps = 12/204 (5%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 V ++TG +SGIGL +A LA+ + L + + LA G + Sbjct: 6 VAVVTGSTSGIGLGIATALAAQGAD-----IVLNGFGDAAEIEKVRAGLAAQHGV--KVL 58 Query: 65 LDVRDSKSVAAARERVTE-----GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGT 119 D D A R V GR+D+LV NAG+ +E + ++L +N+ Sbjct: 59 YDGADLSKGEAVRGLVDNAVRQMGRIDILVNNAGIQHTALIEDFPTEKWDAILALNLSAV 118 Query: 120 VRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGV 179 A LP MK++G GR++ S GL+ Y A+K + G + A+ G+ Sbjct: 119 FHGTAAALPHMKKQGFGRIINIASAHGLVASANKSAYVAAKHGVVGFTKVTALETAGQGI 178 Query: 180 HLSLIECGPVHTAFMEKVLGSPEE 203 + I G V T +EK + + E Sbjct: 179 TANAICPGWVRTPLVEKQISALAE 202 >3EZL-A nrPDB Length = 256 Score = 56.6 bits (135), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 59/223 (26%), Positives = 94/223 (42%), Gaps = 25/223 (11%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLW-EAARALACPPGS 59 M++ + +TG GIG + RL D F+V A + W E +AL + Sbjct: 11 MSQRIAYVTGGMGGIGTSICQRLHKD---GFRVVAGCGPNSPRRVKWLEDQKALGFDFYA 67 Query: 60 LETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVV 117 E +V D S A ++V G +DVLV NAG+ + + +V+D N+ Sbjct: 68 SEG---NVGDWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTREDWQAVIDTNLT 124 Query: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 + + + M RG GR++ SV G G Y +K + G SLA + Sbjct: 125 SLFNVTKQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVATK 184 Query: 178 GVHLSLIECGPVHTAF--------MEKV--------LGSPEEV 204 GV ++ + G + T +EK+ LGSP+E+ Sbjct: 185 GVTVNTVSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGSPDEI 227 >4FC7-A nrPDB Length = 277 Score = 56.6 bits (135), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 52/204 (25%), Positives = 86/204 (42%), Gaps = 7/204 (3%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 V ITG SGIG +A + +L + T R A C P L Sbjct: 29 VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLP-----LS 83 Query: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 +DVR +V AA ++ + GR+D+L+ A L P AL +A +V+D++ GT + Sbjct: 84 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNV 143 Query: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLS 182 + R G ++ + G G ++K A++ + LAV P + ++ Sbjct: 144 SRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 203 Query: 183 LIECGPVHTAFMEKVLGSPEEVLD 206 + GP+ + LG P+ L Sbjct: 204 SLAPGPISGTEGLRRLGGPQASLS 227 >5YSS-A nrPDB Length = 256 Score = 56.6 bits (135), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 51/168 (30%), Positives = 82/168 (48%), Gaps = 10/168 (5%) Query: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLD 66 L+TG +SGIGL +A LA + ATL L G + A A+A + D Sbjct: 9 LVTGSTSGIGLGIAQVLA-------QAGATLI-LNGFGDVDAAKDAVAQYGKTPGYHGAD 60 Query: 67 VRDSKSVA-AARERVTE-GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQ 124 + D +A R +E G VD+L+ NAG+ + P+E D +++ +N+ + Sbjct: 61 LSDEAQIADMMRYAESEFGGVDILINNAGIQHVSPIETFPVDKWNAIIAINLSSVFHTTR 120 Query: 125 AFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAV 172 LP M+ R GR++ SV GL+ Y A+K + GL +++A+ Sbjct: 121 LALPGMRARNWGRIINIASVHGLVASKEKSAYVAAKHGVVGLTKTIAL 168 >4M8S-A nrPDB Length = 248 Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 56/209 (26%), Positives = 95/209 (45%), Gaps = 29/209 (13%) Query: 5 VVLITGCSSGIGLHLA----------VRLASDPSQSFKVYATLRDLKTQGRLWEAARALA 54 + L+TG S GIG +A + A+ S + + L +GR+ +A Sbjct: 10 IALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGGEGRVLNSA---- 65 Query: 55 CPPGSLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDV 114 P ++E L D+ T G++D+LV NAG+ L + E+ ++ V Sbjct: 66 -EPETVENLIADIEK-----------TFGKLDILVNNAGITRDNLLMRMKEEEWDDIMQV 113 Query: 115 NVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLL 174 N+ R +A L M ++ +GR++ SV G+MG Y A+K L G +S+A + Sbjct: 114 NLKSVFRASKAVLRGMMKQRAGRIINITSVVGVMGNAGQTNYAAAKAGLIGFSKSMAREV 173 Query: 175 LPFGVHLSLIECGPVHTAFMEKVLGSPEE 203 G+ ++ + G + T M + L PEE Sbjct: 174 GSRGITVNCVAPGFIDTD-MTRAL--PEE 199 >5VT6-A nrPDB Length = 269 Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 53/210 (25%), Positives = 95/210 (45%), Gaps = 16/210 (7%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLW---EAARALACPPG 58 A+ V +TG G+G ++ RL D + V + R+ L +A R Sbjct: 24 AKRVAFVTGGMGGLGAAISRRL-HDAGMAVAVSHSERNDHVSTWLMHERDAGR------- 75 Query: 59 SLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNV 116 + +DV D +S E+V G+VDVL+ NAG+ + + +V+ ++ Sbjct: 76 DFKAYAVDVADFESCERCAEKVLADFGKVDVLINNAGITRDATFMKMTKGDWDAVMRTDL 135 Query: 117 VGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLP 176 + + F+ M R GR++ GSV G G Y ++K + G ++LA+ Sbjct: 136 DAMFNVTKQFIAGMVERRFGRIVNIGSVNGSRGAFGQANYASAKAGIHGFTKTLALETAK 195 Query: 177 FGVHLSLIECGPVHTAFMEKVLGSPEEVLD 206 G+ ++ + G + TA +E V P++VL+ Sbjct: 196 RGITVNTVSPGYLATAMVEAV---PQDVLE 222 >3OIC-A nrPDB Length = 258 Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 49/187 (26%), Positives = 83/187 (44%), Gaps = 7/187 (3%) Query: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLD 66 L+TG S G+G A+RLA + YA +++ E A + + ++ + Sbjct: 8 LVTGSSRGVGKAAAIRLAENGYNIVINYA-----RSKKAALETAEEIEKLGVKVLVVKAN 62 Query: 67 VRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQ 124 V + +++ E GR+DV V NA G+L P+ L E +++N + Q Sbjct: 63 VGQPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELEETHWDWTMNINAKALLFCAQ 122 Query: 125 AFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLI 184 M++ G G ++ S+G + L SK ALE L LAV L P + ++ + Sbjct: 123 EAAKLMEKNGGGHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAVELSPKQIIVNAV 182 Query: 185 ECGPVHT 191 G + T Sbjct: 183 SGGAIDT 189 >3AUT-A nrPDB Length = 269 Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 54/216 (25%), Positives = 98/216 (45%), Gaps = 19/216 (8%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 VV+ITG S+G+G +AVR + ++ Y + +A + + G +Q Sbjct: 17 VVVITGGSTGLGRAMAVRFGQEEAKVVINY-----YNNEEEALDAKKEVEEAGGQAIIVQ 71 Query: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNV----VG 118 DV + V + + G +DV++ NAG+ P L D V+D N+ +G Sbjct: 72 GDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGAFLG 131 Query: 119 TVRMLQAFLP-DMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 + ++ F+ D+K G V+ SV ++ P Y ASK ++ + E+LA+ P Sbjct: 132 SREAIKYFVENDIK----GNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPK 187 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTF 213 G+ ++ I G ++T + P + R D+ + Sbjct: 188 GIRVNNIGPGAMNTPINAEKFADP---VQRADVESM 220 >4NBT-A nrPDB Length = 240 Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 62/243 (25%), Positives = 108/243 (44%), Gaps = 38/243 (15%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 V +ITG + G+G +A+ A + ++ + L DL + P ++E + Sbjct: 8 VAVITGGAKGLGQAIALAYAEEGAKV--IAGDLGDL-----------TYSHP--NVEGMY 52 Query: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 L+V D V + V + G++D+LV NAG+ + E +V+DVN+ G + Sbjct: 53 LNVTDVTGVEKFYQSVIDKYGKIDILVNNAGITKDAMTRKMTEAQWDAVIDVNLKGVFNL 112 Query: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLA--VLLLPFGVH 180 + P M+ G G ++ SV G+ G Y A+K + GL + A L V Sbjct: 113 TRLVGPQMQTNGYGSIINISSVVGVFGNIGQANYAATKAGVIGLTMTWAKEFALKGANVR 172 Query: 181 LSLIECGPVHTAFMEKVLGSPEEVLDR-TDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE 239 ++ I G + T ++ V P+++LD+ + +R Q PEE+A+ Sbjct: 173 VNAIAPGYIMTDILKTV---PQDLLDKFAALTMLNRLGQ---------------PEEIAK 214 Query: 240 VFL 242 V L Sbjct: 215 VAL 217 >5O3Z-A nrPDB Length = 263 Score = 55.1 bits (131), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 46/142 (32%), Positives = 65/142 (45%), Gaps = 11/142 (7%) Query: 63 LQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 ++D D SV A V E GR D+LV +AG+ P+ L VN+VG Sbjct: 62 FKVDATDEASVEALARAVDETFGRADLLVYSAGVAKAAPITQFRLTDFDLSLQVNLVGYF 121 Query: 121 RMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGV 179 + F M R G GR++ S G +G N Y A+KF GL +SLA+ L +G+ Sbjct: 122 LCSREFSKLMIRDGIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDLAEYGI 181 Query: 180 HLSLIECGPVHTAFMEKVLGSP 201 VH+ + +L SP Sbjct: 182 --------TVHSLMLGNLLKSP 195 >3VZS-A nrPDB Length = 257 Score = 55.1 bits (131), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 55/206 (26%), Positives = 89/206 (43%), Gaps = 12/206 (5%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLW-EAARALACPPGSLETL 63 + +TG GIG + RLA D F+V A + W E +AL + E Sbjct: 16 IAYVTGGMGGIGTAICQRLAKD---GFRVVAGCGPNSPRREKWLEQQKALGFDFIASEG- 71 Query: 64 QLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 +V D S A ++V G VDVL+ NAG+ + +V+D N+ Sbjct: 72 --NVADWDSTKTAFDKVKSEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFN 129 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 + + + M RG GR++ SV G G Y +K L G +LA + GV + Sbjct: 130 VTKQVIDGMADRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTV 189 Query: 182 SLIECGPVHTAFMEKVLGSPEEVLDR 207 + + G + T ++ + ++VLD+ Sbjct: 190 NTVSPGYIATDMVKAI---RQDVLDK 212 >3OML-A nrPDB Length = 613 Score = 55.1 bits (131), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 35/91 (38%), Positives = 51/91 (56%), Gaps = 2/91 (2%) Query: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142 GRVD+LV NAG+ L E V DV++ G+ + QA P MK++ GR+++T Sbjct: 101 GRVDILVNNAGILRDRSLVKTSEQDWNLVNDVHLKGSFKCTQAAFPYMKKQNYGRIIMTS 160 Query: 143 SVGGLMGLPFNDV-YCASKFALEGLCESLAV 172 S G+ G F V Y A+K L GL ++A+ Sbjct: 161 SNSGIYG-NFGQVNYTAAKMGLIGLANTVAI 190 >2NWQ-A nrPDB Length = 272 Score = 54.7 bits (130), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 70/255 (27%), Positives = 105/255 (41%), Gaps = 40/255 (15%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET- 62 + + ITG +SG G A R A L GR E +ALA G L Sbjct: 22 STLFITGATSGFGEACARRFAEAG----------WSLVLTGRREERLQALA---GELSAK 68 Query: 63 -----LQLDVRDSKSVAAARERVTEGRVDV--LVCNAGLGL-LGPLEALGEDAVASVLDV 114 L LDVRD +++AA + + E + L+ NAGL L P ++ D +++D Sbjct: 69 TRVLPLTLDVRDRAAMSAAVDNLPEEFATLRGLINNAGLALGTDPAQSCDLDDWDTMVDT 128 Query: 115 NVVGTVRMLQAFLPDMKRRGSGRVLVT-GSVGGLMGLPFNDVYCASKFALEGLCESLAVL 173 N+ G + + LP + G+G +V GSV G P + VY +K +E +L Sbjct: 129 NIKGLLYSTRLLLPRLIAHGAGASIVNLGSVAGKWPYPGSHVYGGTKAFVEQFSLNLRCD 188 Query: 174 LLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQN 233 L GV ++ +E G + F G + D+T AH Q Sbjct: 189 LQGTGVRVTNLEPGLCESEFSLVRFGGDQARYDKTYAG---------AHPIQ-------- 231 Query: 234 PEEVAEVFLTALRAP 248 PE++AE + P Sbjct: 232 PEDIAETIFWIMNQP 246 >3V8B-A nrPDB Length = 283 Score = 54.7 bits (130), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 49/145 (33%), Positives = 73/145 (50%), Gaps = 9/145 (6%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 V LITG SGIG A+ LA+D V A R T+ + E A + G L+ Sbjct: 30 VALITGAGSGIGRATALALAAD---GVTVGALGR---TRTEVEEVADEIVGAGGQAIALE 83 Query: 65 LDVRDSKSV-AAARERVTE-GRVDVLVCNAGL-GLLGPLEALGEDAVASVLDVNVVGTVR 121 DV D + A R+ V + G +D++V NAG+ G+ P++ L + VN+ GT Sbjct: 84 ADVSDELQMRNAVRDLVLKFGHLDIVVANAGINGVWAPIDDLKPFEWDETIAVNLRGTFL 143 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGG 146 L +P +K+RG G ++V S+ G Sbjct: 144 TLHLTVPYLKQRGGGAIVVVSSING 168 >3E9N-A nrPDB Length = 245 Score = 54.7 bits (130), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 62/241 (25%), Positives = 103/241 (42%), Gaps = 36/241 (14%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + + + ++TG + G+G + + D S+ VYA GR E ALA G + Sbjct: 3 LKKKIAVVTGATGGMG----IEIVKDLSRDHIVYAL-------GRNPEHLAALAEIEG-V 50 Query: 61 ETLQLDVRDSKSVAAARERVTEG---------RVDVLVCNAGLGLLGPLEALGEDAVASV 111 E ++ D+ +E + EG VD LV A + +EA + Sbjct: 51 EPIESDI--------VKEVLEEGGVDKLKNLDHVDTLVHAAAVARDTTIEAGSVAEWHAH 102 Query: 112 LDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLA 171 LD+NV+ + + LP + R SG V+ S G P N +Y ASK AL GL ++ Sbjct: 103 LDLNVIVPAELSRQLLPAL-RAASGCVIYINSGAGNGPHPGNTIYAASKHALRGLADAFR 161 Query: 172 VLLLPFGVHLSLIECGPVHTAFMEKVLGS------PEEVLDRTDIHTFHRFYQYLAHSKQ 225 G+ +S + GP +T ++ ++ S PE ++ +I RF + Q Sbjct: 162 KEEANNGIRVSTVSPGPTNTPMLQGLMDSQGTNFRPEIYIEPKEIANAIRFVIDAGETTQ 221 Query: 226 V 226 + Sbjct: 222 I 222 >3UF0-A nrPDB Length = 273 Score = 54.3 bits (129), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 63/191 (32%), Positives = 86/191 (45%), Gaps = 9/191 (4%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 62 RT V +TG SGIG +A A + L +T G + E A +A GS E Sbjct: 32 RTAV-VTGAGSGIGRAIAHGYARAGAH------VLAWGRTDG-VKEVADEIADGGGSAEA 83 Query: 63 LQLDVRDSKSVA-AARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 + D+ D + A A E RVDVLV NAG+ P E + VL VN+ Sbjct: 84 VVADLADLEGAANVAEELAATRRVDVLVNNAGIIARAPAEEVSLGRWREVLTVNLDAAWV 143 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 + ++F M GSGR++ S+ G Y ASK A+ GL +LA GV + Sbjct: 144 LSRSFGTAMLAHGSGRIVTIASMLSFQGGRNVAAYAASKHAVVGLTRALASEWAGRGVGV 203 Query: 182 SLIECGPVHTA 192 + + G V TA Sbjct: 204 NALAPGYVVTA 214 >1AE1-A nrPDB Length = 273 Score = 54.3 bits (129), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 46/195 (23%), Positives = 82/195 (42%), Gaps = 3/195 (1%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETL 63 T L+TG S GIG + LA ++ + ++L +W + L + L Sbjct: 22 TTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWRE-KGLNVEGSVCDLL 80 Query: 64 QLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRML 123 RD A V +G++++LV NAG+ + + E ++ N + Sbjct: 81 SRTERDKLMQTVAH--VFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFEAAYHLS 138 Query: 124 QAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSL 183 Q P +K +G V+ S+ G LP +Y ASK A+ + +SLA + ++ Sbjct: 139 QIAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLACEWAKDNIRVNS 198 Query: 184 IECGPVHTAFMEKVL 198 + G + T +E + Sbjct: 199 VAPGVILTPLVETAI 213 >2UVD-A nrPDB Length = 246 Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 50/189 (26%), Positives = 87/189 (46%), Gaps = 7/189 (3%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 V L+TG S GIG +A+ LA + YA + + E + ++ Sbjct: 6 VALVTGASRGIGRAIAIDLAKQGANVVVNYA-----GNEQKANEVVDEIKKLGSDAIAVR 60 Query: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 DV +++ V ++ + G+VD+LV NAG+ L + E+ +V++ N+ G Sbjct: 61 ADVANAEDVTNMVKQTVDVFGQVDILVNNAGVTKDNLLMRMKEEEWDTVINTNLKGVFLC 120 Query: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLS 182 +A M R+ GR++ SV G+ G P Y A+K + GL ++ A L + ++ Sbjct: 121 TKAVSRFMMRQRHGRIVNIASVVGVTGNPGQANYVAAKAGVIGLTKTSAKELASRNITVN 180 Query: 183 LIECGPVHT 191 I G + T Sbjct: 181 AIAPGFIAT 189 >4IS3-A nrPDB Length = 268 Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 57/243 (23%), Positives = 97/243 (39%), Gaps = 29/243 (11%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRD-----LKTQGRLWEAARALACPPGS 59 V +ITG + GIG A ++ D ++ ++ L L+ L P Sbjct: 27 VTIITGGTRGIGFA-AAKIFIDNGAKVSIFGETQEEVDTALAQLKELYPEEEVLGFAP-- 83 Query: 60 LETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGT 119 L RD+ A + GR+DV++ NAG+ + E+ ++D+NV G Sbjct: 84 ----DLTSRDAVMAAVGQVAQKYGRLDVMINNAGITSNNVFSRVSEEEFKHIMDINVTGV 139 Query: 120 VRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGV 179 MK G ++ T SV G+ G Y ASK ++ GL L ++ + Sbjct: 140 FNGAWCAYQCMKDAKKGVIINTASVTGIFGSLSGVGYPASKASVIGLTHGLGREIIRKNI 199 Query: 180 HLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE 239 + + G V+T G+P E+++ + K + + PEE+A Sbjct: 200 RVVGVAPGVVNTDMTN---GNPPEIME--------------GYLKALPMKRMLEPEEIAN 242 Query: 240 VFL 242 V+L Sbjct: 243 VYL 245 >3UN1-A nrPDB Length = 260 Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 59/194 (30%), Positives = 95/194 (48%), Gaps = 21/194 (10%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGR--LWEAARALACPPGSL 60 + VV+ITG S GIG L VR D ++++V AT R +K + A ++ P Sbjct: 28 QKVVVITGASQGIGAGL-VRAYRD--RNYRVVATSRSIKPSADPDIHTVAGDISKP---- 80 Query: 61 ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 ET VR+ ER GR+D LV NAG+ L P + ++ L VNV G Sbjct: 81 ETADRIVREGI------ERF--GRIDSLVNNAGVFLAKPFVEMTQEDYDHNLGVNVAGFF 132 Query: 121 RMLQAFLPDMKRRGSGRVL-VTGSVGG--LMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 + Q +M ++GSG ++ +T S+ ++G+P + + +K L + SLA+ Sbjct: 133 HITQRAAAEMLKQGSGHIVSITTSLVDQPMVGMP-SALASLTKGGLNAVTRSLAMEFSRS 191 Query: 178 GVHLSLIECGPVHT 191 GV ++ + G + T Sbjct: 192 GVRVNAVSPGVIKT 205 >3V2G-A nrPDB Length = 271 Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 58/195 (29%), Positives = 90/195 (46%), Gaps = 12/195 (6%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 +A +TG S GIG +A RLA + + Y + + Q + E +A G Sbjct: 29 LAGKTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAE-RAQAVVSEIEQA----GGRA 83 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 ++ D RD++++ A E G +D+LV +AG+ PLE E VA +V V Sbjct: 84 VAIRADNRDAEAIEQAIRETVEALGGLDILVNSAGIWHSAPLE---ETTVADFDEVMAVN 140 Query: 119 TVRMLQAFLPDMKRRGS-GRVLVTGS-VGGLMGLPFNDVYCASKFALEGLCESLAVLLLP 176 A + G GR++ GS + L+ P +Y ASK AL GL + LA L P Sbjct: 141 FRAPFVAIRSASRHLGDGGRIITIGSNLAELVPWPGISLYSASKAALAGLTKGLARDLGP 200 Query: 177 FGVHLSLIECGPVHT 191 G+ ++++ G T Sbjct: 201 RGITVNIVHPGSTDT 215 >4MOW-A nrPDB Length = 256 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 58/201 (28%), Positives = 90/201 (44%), Gaps = 25/201 (12%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLR---DLKTQGRLWEAARALACPP 57 +A V ++TG S GIG +A LA + + YA+ + D RA+A Sbjct: 12 LAGKVAIVTGASKGIGAAIAKALADEGAAVVVNYASSKAGADAVVSAITEAGGRAVA--- 68 Query: 58 GSLETLQLDVRDSKSVAAARERV------TEGRVDVLVCNAGLGLLGPLEALGEDAVASV 111 V S AA +R+ T GR+DVLV N+G+ P+EA+ E+ Sbjct: 69 ---------VGGDVSKAADAQRIVDTAIETYGRLDVLVNNSGVYEFAPIEAITEEHYRRQ 119 Query: 112 LDVNVVGTVRMLQAFLPDMKRRGSGRVLVT-GSVGGLMGLPFNDVYCASKFALEGLCESL 170 D NV G + QA + K G G ++ SV + P + VY +K A++ + L Sbjct: 120 FDTNVFGVLLTTQAAV---KHLGEGASIINISSVVTSITPPASAVYSGTKGAVDAITGVL 176 Query: 171 AVLLLPFGVHLSLIECGPVHT 191 A+ L P + ++ I G + T Sbjct: 177 ALELGPRKIRVNAINPGMIVT 197 >1GEE-A nrPDB Length = 261 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 55/216 (25%), Positives = 102/216 (47%), Gaps = 19/216 (8%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 VV+ITG S+G+G +A+R A++ ++ Y + D + L E + G ++ Sbjct: 9 VVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKED-EANSVLEEIKKV----GGEAIAVK 63 Query: 65 LDVR-DSKSVAAARERVTE-GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNV----VG 118 DV +S + + + E G++DV++ NAGL + V+D N+ +G Sbjct: 64 GDVTVESDVINLVQSAIKEFGKLDVMINNAGLENPVSSHEMSLSDWNKVIDTNLTGAFLG 123 Query: 119 TVRMLQAFLP-DMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 + ++ F+ D+K G V+ SV + P Y ASK ++ + E+LA+ P Sbjct: 124 SREAIKYFVENDIK----GTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALEYAPK 179 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTF 213 G+ ++ I G ++T + PE+ R D+ + Sbjct: 180 GIRVNNIGPGAINTPINAEKFADPEQ---RADVESM 212 >4RZH-A nrPDB Length = 247 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 36/118 (30%), Positives = 60/118 (50%) Query: 84 RVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGS 143 R+DVLV NAG+ L + + +V+D+N+ G +A M ++ SGR++ S Sbjct: 84 RIDVLVNNAGITRDTLLLRMKLEDWQAVIDLNLTGVFLCTKAVSKLMLKQKSGRIINITS 143 Query: 144 VGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSP 201 V G+MG P Y A+K + G +++A L GV ++ + G + T E + P Sbjct: 144 VAGMMGNPGQANYSAAKAGVIGFTKTVAKELASRGVTVNAVAPGFIATDMTENLNAEP 201 >3F9I-A nrPDB Length = 249 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 47/191 (24%), Positives = 87/191 (45%), Gaps = 11/191 (5%) Query: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLD 66 LITG SSGIG +A L S+ + LK+ G + ++E L Sbjct: 18 LITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALK-------DNYTIEVCNLA 70 Query: 67 VRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAF 126 ++ S ++ +D+LVCNAG+ + + V+D+N+ + + Sbjct: 71 NKEECSNLISKT----SNLDILVCNAGITSDTLAIRMKDQDFDKVIDINLKANFILNREA 126 Query: 127 LPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIEC 186 + M ++ GR++ S+ G+ G P YCASK L G+ +SL+ + G+ ++ + Sbjct: 127 IKKMIQKRYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYEVATRGITVNAVAP 186 Query: 187 GPVHTAFMEKV 197 G + + +K+ Sbjct: 187 GFIKSDMTDKL 197 >3FTP-A nrPDB Length = 270 Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 62/223 (27%), Positives = 101/223 (45%), Gaps = 30/223 (13%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 62 + V ++TG S GIG +A+ LA + T + G ++ A LE Sbjct: 28 KQVAIVTGASRGIGRAIALELARRGAMVIGTATTEAGAEGIGAAFKQA--------GLEG 79 Query: 63 --LQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 L+V D+ +V A E + G ++VLV NAG+ + +D +V+D N+ Sbjct: 80 RGAVLNVNDATAVDALVESTLKEFGALNVLVNNAGITQDQLAMRMKDDEWDAVIDTNLKA 139 Query: 119 TVRMLQAFL-PDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 R+ +A L P MK RG GR++ SV G G P Y A+K + G+ +LA + Sbjct: 140 VFRLSRAVLRPMMKARG-GRIVNITSVVGSAGNPGQVNYAAAKAGVAGMTRALAREIGSR 198 Query: 178 GVHLSLIECGPV------------HTAFMEKV----LGSPEEV 204 G+ ++ + G + TA ++ LGSPE++ Sbjct: 199 GITVNCVAPGFIDTDMTKGLPQEQQTALKTQIPLGRLGSPEDI 241 >4IIV-A nrPDB Length = 267 Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 54/198 (27%), Positives = 87/198 (43%), Gaps = 9/198 (4%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 M+R+V L+TG S GIG +A +LA+D F + + E A+ G+ Sbjct: 25 MSRSV-LVTGASKGIGRAIARQLAAD---GFNIGVHYH--RDAAGAQETLNAIVANGGNG 78 Query: 61 ETLQLDV--RDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 L DV R+ E G +V NAG+ AL D +V+ N+ Sbjct: 79 RLLSFDVANREQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPALSNDDWDAVIHTNLDS 138 Query: 119 TVRMLQ-AFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 ++Q +P + R GR++ SV G+MG Y A+K + G ++LA+ L Sbjct: 139 FYNVIQPCIMPMIGARQGGRIITLSSVSGVMGNRGQVNYSAAKAGIIGATKALAIELAKR 198 Query: 178 GVHLSLIECGPVHTAFME 195 + ++ I G + T +E Sbjct: 199 KITVNCIAPGLIDTGMIE 216 >3RWB-A nrPDB Length = 247 Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 55/212 (25%), Positives = 91/212 (42%), Gaps = 27/212 (12%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLK------TQGRLWEAARALA 54 +A L+TG + GIG +A RLA+D + + D+ + + ARA+A Sbjct: 4 LAGKTALVTGAAQGIGKAIAARLAADGATVI-----VSDINAEGAKAAAASIGKKARAIA 58 Query: 55 CPPGSLETLQLDVRDSKSVAA--ARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVL 112 D+ D SV A A + G +D+LV NA + + + D ++ Sbjct: 59 A----------DISDPGSVKALFAEIQALTGGIDILVNNASIVPFVAWDDVDLDHWRKII 108 Query: 113 DVNVVGTVRMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLA 171 DVN+ GT + +A M+ G +GRV+ S G P Y A+K + G +LA Sbjct: 109 DVNLTGTFIVTRAGTDQMRAAGKAGRVISIASNTFFAGTPNMAAYVAAKGGVIGFTRALA 168 Query: 172 VLLLPFGVHLSLIECGPVHTAFMEKVLGSPEE 203 L + + + + G + + + V SP Sbjct: 169 TELGKYNITANAVTPGLIES---DGVKASPHN 197 >2PH3-A nrPDB Length = 245 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 67/247 (27%), Positives = 108/247 (43%), Gaps = 29/247 (11%) Query: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGS--LETLQ 64 LITG S GIG +A+RLA D +A E A GS + L Sbjct: 5 LITGASRGIGRAIALRLAEDG------FALAIHYGQNREKAEEVAEEARRRGSPLVAVLG 58 Query: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 ++ ++++ A + E G +D LV NAG+ L + ++ +VL+ N+ R Sbjct: 59 ANLLEAEAATALVHQAAEVLGGLDTLVNNAGITRDTLLVRMKDEDWEAVLEANLSAVFRT 118 Query: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLS 182 + + M + GR++ SV G++G P Y ASK L G ++A G+ ++ Sbjct: 119 TREAVKLMMKARFGRIVNITSVVGILGNPGQANYVASKAGLIGFTRAVAKEYAQRGITVN 178 Query: 183 LIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE--V 240 + G + T E++ P+EV + A+ KQ+ PEEVAE Sbjct: 179 AVAPGFIETEMTERL---PQEVKE--------------AYLKQIPAGRFGRPEEVAEAVA 221 Query: 241 FLTALRA 247 FL + +A Sbjct: 222 FLVSEKA 228 >5U9P-A nrPDB Length = 265 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 51/187 (27%), Positives = 82/187 (43%), Gaps = 8/187 (4%) Query: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLD 66 LITG GIGL LA LA + A + + + + + AR + + D Sbjct: 24 LITGSGRGIGLTLARGLAEAGA------AIVINDRNEEKAATLARRFRDEGFAADHAVFD 77 Query: 67 VRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQ 124 V + V AA + G +D+LV NAG+ PL+A D +++ VN+ G + Q Sbjct: 78 VAEHAQVRAAIDEFEARVGAIDILVNNAGIQRRAPLDAFEPDDWHALMRVNLDGVFNVAQ 137 Query: 125 AFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLI 184 A M RG G+++ SV + P Y A+K A+ L + + +G+ + + Sbjct: 138 AVARHMIARGHGKIINICSVQSELARPTIAPYAATKGAVRMLTKGMCADWARYGIQANGL 197 Query: 185 ECGPVHT 191 G T Sbjct: 198 APGYFET 204 >3PXX-A nrPDB Length = 287 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 49/156 (31%), Positives = 77/156 (49%), Gaps = 20/156 (12%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE--- 61 VVL+TG + G G AV+LA + + ++ D++T +R L +E Sbjct: 12 VVLVTGGARGQGRSHAVKLAEEGAD-IILFDICHDIETNEYPLATSRDLEEAGLEVEKTG 70 Query: 62 ----TLQLDVRDSKSVA--AARERVTEGRVDVLVCNAGLGLLG---PLEALGEDAVASVL 112 T ++DVRD +V+ A G++DV+V NAG+ LG P++A A Sbjct: 71 RKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANAGICPLGAHLPVQAF-----ADAF 125 Query: 113 DVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLM 148 DV+ VG + + A LP + S ++ TGSV GL+ Sbjct: 126 DVDFVGVINTVHAALPYLTSGAS--IITTGSVAGLI 159 >1O5I-A nrPDB Length = 249 Score = 51.6 bits (122), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 32/128 (25%), Positives = 68/128 (53%), Gaps = 6/128 (4%) Query: 78 ERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGR 137 E+V E VD+LV NAG G + L + +D + +++++ +LP MK +G GR Sbjct: 77 EKVKE--VDILVLNAGGPKAGFFDELTNEDFKEAIDSLFLNMIKIVRNYLPAMKEKGWGR 134 Query: 138 VLVTGSVGGLMGLPFNDVYCAS--KFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFME 195 ++ S + P ++Y ++ + AL G ++L+ + P+G+ ++ + G T ++ Sbjct: 135 IVAITSFSVIS--PIENLYTSNSARMALTGFLKTLSFEVAPYGITVNCVAPGWTETERVK 192 Query: 196 KVLGSPEE 203 ++L ++ Sbjct: 193 ELLSEEKK 200 >4TRR-A nrPDB Length = 269 Score = 50.8 bits (120), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 56/201 (27%), Positives = 89/201 (44%), Gaps = 13/201 (6%) Query: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLD 66 ++TG +SGIG +A+ LA + + DL G A + G + +D Sbjct: 18 VVTGAASGIGKEIALELAKAGAAV-----AIADLNQDGAN-AVADEINKAGGKAIGVAMD 71 Query: 67 VRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQ 124 V + ++V ++V E G VD+LV NAG+ ++ P+E + ++V G + Sbjct: 72 VTNEEAVNTGIDKVAEAFGSVDILVSNAGIQIVNPIENYSFADWKKMQAIHVDGAFLTTK 131 Query: 125 AFLPDMKR--RGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLS 182 A L M + RG G V+ GSV P Y +K L GL LA V Sbjct: 132 AALKHMYKDDRG-GVVIYMGSVHSHEASPLKSAYVTAKHGLLGLARVLAKEGAKHNVRSH 190 Query: 183 LIECGPVHTAFMEKVLGSPEE 203 ++ G V T ++K + PE+ Sbjct: 191 VVCPGFVRTPLVDKQI--PEQ 209 >2Q2Q-A nrPDB Length = 255 Score = 50.8 bits (120), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 54/201 (26%), Positives = 91/201 (45%), Gaps = 28/201 (13%) Query: 7 LITGCSSGIGLHLAVRLA-----------SDPSQSFKVYATLRDLKTQGRLWEAARALAC 55 L+TG +SGIGL +A LA DP+ + L ++ G +A+ Sbjct: 8 LVTGSTSGIGLGIAQVLARAGANIVLNGFGDPAPA------LAEIARHG-----VKAVHH 56 Query: 56 PPGSLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVN 115 P + Q++ ++ A ER G VD+LV NAG+ + P+E ++ ++ +N Sbjct: 57 PADLSDVAQIE-----ALFALAER-EFGGVDILVNNAGIQHVAPVEQFPLESWDKIIALN 110 Query: 116 VVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLL 175 + + LP M+ R GR++ SV GL+G Y A+K + GL + + + Sbjct: 111 LSAVFHGTRLALPGMRARNWGRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGLETA 170 Query: 176 PFGVHLSLIECGPVHTAFMEK 196 V + I G V T ++K Sbjct: 171 TSNVTCNAICPGWVLTPLVQK 191 >2HQ1-A nrPDB Length = 247 Score = 50.4 bits (119), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 52/222 (23%), Positives = 90/222 (40%), Gaps = 35/222 (15%) Query: 7 LITGCSSGIGLHLAVRLASDPSQ--------SFKVYATLRDLKTQGRLWEAARALACPPG 58 ++TG S G+G +A +L + + S + AT + K G A+ P Sbjct: 9 IVTGSSRGLGKAIAWKLGNMGANIVLNGSPASTSLDATAEEFKAAGINVVVAKGDVKNPE 68 Query: 59 SLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 +E + D+ GR+D+LV NAG+ + + E VL+ N+ Sbjct: 69 DVENMVKTAMDA-----------FGRIDILVNNAGITRDTLMLKMSEKDWDDVLNTNLKS 117 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 +A M ++ SG+++ S+ G++G Y ASK L G +S+A G Sbjct: 118 AYLCTKAVSKIMLKQKSGKIINITSIAGIIGNAGQANYAASKAGLIGFTKSIAKEFAAKG 177 Query: 179 VHLSLIECGPVHTAFME----------------KVLGSPEEV 204 ++ + + G + T + K G+PEEV Sbjct: 178 IYCNAVAPGIIKTDMTDVLPDKVKEMYLNNIPLKRFGTPEEV 219 >4RZI-B nrPDB Length = 240 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 58/215 (26%), Positives = 93/215 (43%), Gaps = 22/215 (10%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 V+++TG + GIG + L Q DL T G EA +A Sbjct: 10 VIVVTGGNRGIGAAIVKLL-----QEMGAKVAFTDLATDGGNTEALGVVA---------- 54 Query: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 +V D +S+ AA +T+ G V +V NAG+ L +VL+VN+ G Sbjct: 55 -NVTDLESMTAAAAEITDKLGPVYGVVANAGITKDNFFPKLTPADWDAVLNVNLKGVAYS 113 Query: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLS 182 ++ F+ M R +G ++ S+ G G Y A+K + G+ +SLA +GV + Sbjct: 114 IKPFIEGMYERKAGSIVAISSISGERGNVGQTNYSATKAGVIGMMKSLAREGARYGVRAN 173 Query: 183 LIECGPVHTAFMEKVLGSPEEVLDR-TDIHTFHRF 216 + G + T E L E++ ++ T F RF Sbjct: 174 AVAPGFIDT---EMTLAIREDIREKITKEIPFRRF 205 >2PNF-A nrPDB Length = 248 Score = 50.1 bits (118), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 65/226 (28%), Positives = 101/226 (44%), Gaps = 35/226 (15%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQG-RLWEAARALACPPG-SLET 62 V L+TG + GIG +A +LAS S T+ T G R A +A G Sbjct: 9 VSLVTGSTRGIGRAIAEKLASAGS-------TVIITGTSGERAKAVAEEIANKYGVKAHG 61 Query: 63 LQLDVRDSKSVAAARERV---TEGRVDVLVCNAGL---GLLGPLEALGEDAVASVLDVNV 116 +++++ +S+ A E + +G +D+LV NAG+ L + L + VL VN+ Sbjct: 62 VEMNLLSEESINKAFEEIYNLVDG-IDILVNNAGITRDKLFLRMSLLDWE---EVLKVNL 117 Query: 117 VGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLP 176 GT + Q L M ++ GR++ SV G G Y +K L G +SLA L P Sbjct: 118 TGTFLVTQNSLRKMIKQRWGRIVNISSVVGFTGNVGQVNYSTTKAGLIGFTKSLAKELAP 177 Query: 177 FGVHLSLIECGPVHT------------AFMEKV----LGSPEEVLD 206 V ++ + G + T + E++ GSPEEV + Sbjct: 178 RNVLVNAVAPGFIETDMTAVLSEEIKQKYKEQIPLGRFGSPEEVAN 223 >3D3W-A nrPDB Length = 244 Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 54/212 (25%), Positives = 96/212 (45%), Gaps = 16/212 (7%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 VL+TG GIG L + ++ V T DL + R CP +E + + Sbjct: 10 VLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVR--------ECP--GIEPVCV 59 Query: 66 DVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQA 125 D+ D + A R + G VD+LV NA + LL P + ++A +VN+ +++ Q Sbjct: 60 DLGDWE--ATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQI 117 Query: 126 FLPDMKRRGS-GRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLI 184 + RG G ++ S + + VYC++K AL+ L + +A+ L P + ++ + Sbjct: 118 VARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAV 177 Query: 185 ECGPVHTAFMEKVLGSPEE---VLDRTDIHTF 213 V T+ + P + +L+R + F Sbjct: 178 NPTVVMTSMGQATWSDPHKAKTMLNRIPLGKF 209 >2AG5-A nrPDB Length = 246 Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 45/151 (29%), Positives = 73/151 (48%), Gaps = 7/151 (4%) Query: 57 PGSLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNV 116 PG ++T LDV K + V R+DVL AG G + E +++NV Sbjct: 50 PG-IQTRVLDVTKKKQIDQFANEVE--RLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNV 106 Query: 117 VGTVRMLQAFLPDMKRRGSGRVLVTGSVG-GLMGLPFNDVYCASKFALEGLCESLAVLLL 175 M++AFLP M + SG ++ SV + G+ VY +K A+ GL +S+A + Sbjct: 107 RSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFI 166 Query: 176 PFGVHLSLIECGPVHTAFMEKVL---GSPEE 203 G+ + + G V T +++ + G+PEE Sbjct: 167 QQGIRCNCVCPGTVDTPSLQERIQARGNPEE 197 >2CDH-G nrPDB Length = 244 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 48/169 (28%), Positives = 75/169 (44%), Gaps = 7/169 (4%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 VV++TG S GIG +A+ L + YA R K E ++ + G T Sbjct: 3 VVVVTGASRGIGKAIALSLGKAGCKVLVNYA--RSAKAAE---EVSKQIEAYGGQAITFG 57 Query: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 DV V A + + G +DV+V NAG+ L + + V+D+N+ G Sbjct: 58 GDVSKEADVEAMMKTAIDAWGTIDVVVNNAGITRDTLLIRMKKSQWDEVIDLNLTGVFLC 117 Query: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLA 171 QA M ++ GR++ SV GL+G Y A+K + G ++ A Sbjct: 118 TQAATKIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAA 166 >6NRP-A nrPDB Length = 263 Score = 48.9 bits (115), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 51/189 (26%), Positives = 86/189 (45%), Gaps = 8/189 (4%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 +L+TG S GIG +A++LA F V T+ Q + + + + L Sbjct: 27 ILVTGSSRGIGKAIALQLAK---AGFDV--TVHARSRQAEAEQVVQEIQALGQNSHYLMF 81 Query: 66 DVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRML 123 DV + ++V E+ E G +V NAGL G AL + V+ ++ G +L Sbjct: 82 DVNERQTVQQILEQDVEQHGGFYGVVLNAGLTHDGAFPALTDQDWDEVISTSLDGFYNVL 141 Query: 124 Q-AFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLS 182 + +P + R GR++ SV G+MG Y A+K L G ++LA+ L + ++ Sbjct: 142 KPLIMPMIHLRKGGRIVTLSSVSGIMGNRGQVNYSAAKAGLIGATKALALELAKRKITVN 201 Query: 183 LIECGPVHT 191 + G + T Sbjct: 202 CVAPGLIET 210 >1CYD-A nrPDB Length = 244 Score = 48.1 bits (113), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 53/213 (24%), Positives = 92/213 (43%), Gaps = 13/213 (6%) Query: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLD 66 L+TG GIG L + ++ V T DL + A CP +E + +D Sbjct: 11 LVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDL--------VSLAKECP--GIEPVCVD 60 Query: 67 VRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAF 126 + D + A + G VD+LV NA L ++ P + ++A VN+ ++ Q Sbjct: 61 LGDWDATEKALGGI--GPVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNLRSVFQVSQMV 118 Query: 127 LPDMKRRGS-GRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIE 185 DM RG G ++ S+ + P Y ++K A+ L +++A+ L P + ++ + Sbjct: 119 ARDMINRGVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMELGPHKIRVNSVN 178 Query: 186 CGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQ 218 V T +KV PE + H +F + Sbjct: 179 PTVVLTDMGKKVSADPEFARKLKERHPLRKFAE 211 >4CQM-B nrPDB Length = 244 Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 53/190 (27%), Positives = 86/190 (45%), Gaps = 13/190 (6%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE-TL 63 V + G S GIG +A +A + +++ R+L E A+A A G Sbjct: 11 VCAVFGGSRGIGRAVAQLMAR---KGYRLAVIARNL-------EGAKAAAGDLGGDHLAF 60 Query: 64 QLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 DV V E + + GRV+ LV AG+ G L + + S L N++G++ Sbjct: 61 SCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSML 120 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 +A + M ++ G ++ GS+ GL G VY ASK L G +LA + + + Sbjct: 121 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 180 Query: 182 SLIECGPVHT 191 +++ G VHT Sbjct: 181 NVVAPGFVHT 190 >1SNY-A nrPDB Length = 267 Score = 47.8 bits (112), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 56/220 (25%), Positives = 100/220 (45%), Gaps = 28/220 (12%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 +LITGC+ G+GL L L + P ++ T R+ + L + A+ + ++ L++ Sbjct: 24 ILITGCNRGLGLGLVKALLNLPQPPQHLFTTCRNREQAKELEDLAKNHS----NIHILEI 79 Query: 66 DVRD---SKSVAAARERVTEGR-VDVLVCNAGLGLLGP-LEALGEDAVASVLDVNVVGTV 120 D+R+ + A E VT+ + ++VL NAG+ + A+ + L N V + Sbjct: 80 DLRNFDAYDKLVADIEGVTKDQGLNVLFNNAGIAPKSARITAVRSQELLDTLQTNTVVPI 139 Query: 121 RMLQAFLPDMKR---------RGSGR---VLVTGSVGGLMGLPFNDVYC--ASKFALEGL 166 + +A LP +K+ G GR + ++ +G + G +Y SK AL Sbjct: 140 MLAKACLPLLKKAAKANESQPMGVGRAAIINMSSILGSIQGNTDGGMYAYRTSKSALNAA 199 Query: 167 CESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLD 206 +SL+V L P I C +H +++ +G LD Sbjct: 200 TKSLSVDLYP-----QRIMCVSLHPGWVKTDMGGSSAPLD 234 >2AE2-A nrPDB Length = 260 Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 44/203 (21%), Positives = 86/203 (42%), Gaps = 15/203 (7%) Query: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLD 66 L+TG S GIG + LAS + + ++L W + ++ Sbjct: 13 LVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGF---------KVEAS 63 Query: 67 VRDSKSVAAARERVT------EGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 V D S + +E + G++++LV NAG+ + + + + ++ +N Sbjct: 64 VCDLSSRSERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINFEAAY 123 Query: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180 + P +K G V+ SV G + +P+ VY A+K A++ L LA + Sbjct: 124 HLSVLAHPFLKASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAFEWAKDNIR 183 Query: 181 LSLIECGPVHTAFMEKVLGSPEE 203 ++ + G + T+ +E + PE+ Sbjct: 184 VNGVGPGVIATSLVEMTIQDPEQ 206 >2O23-A nrPDB Length = 265 Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 60/212 (28%), Positives = 93/212 (43%), Gaps = 29/212 (13%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAAR---ALACPPGSLE 61 V +ITG +SG+GL A RL + A L DL G +A + P + Sbjct: 14 VAVITGGASGLGLATAERLVGQGAS-----AVLLDLPNSGGEAQAKKLGNNCVFAPADV- 67 Query: 62 TLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVAS------VLDVN 115 T + DV+ + ++A + GRVDV V AG+ + L + + VLDVN Sbjct: 68 TSEKDVQTALALAKGKF----GRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 123 Query: 116 VVGTVRMLQAFLPDMKRR------GSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCES 169 ++GT +++ +M + G ++ T SV G Y ASK + G+ Sbjct: 124 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 183 Query: 170 LAVLLLPFGVHLSLIECG----PVHTAFMEKV 197 +A L P G+ + I G P+ T+ EKV Sbjct: 184 IARDLAPIGIRVMTIAPGLFGTPLLTSLPEKV 215 >4HP8-A nrPDB Length = 247 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 51/190 (26%), Positives = 83/190 (43%), Gaps = 12/190 (6%) Query: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLD 66 L+TG ++G+G +AV LA+ ++ D E +A G+ L +D Sbjct: 13 LVTGANTGLGQAIAVGLAAAGAEVVCAARRAPD--------ETLDIIAKDGGNASALLID 64 Query: 67 VRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAF 126 D AA++ T+ D+LV NAG+ E V+DVN+ QAF Sbjct: 65 FADP---LAAKDSFTDAGFDILVNNAGIIRRADSVEFSELDWDEVMDVNLKALFFTTQAF 121 Query: 127 LPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIE 185 ++ +G SG+V+ S+ G Y A+K + GL + LA G++++ I Sbjct: 122 AKELLAKGRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTKLLANEWAAKGINVNAIA 181 Query: 186 CGPVHTAFME 195 G + T E Sbjct: 182 PGYIETNNTE 191 >5PGZ-A nrPDB Length = 276 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 56/192 (29%), Positives = 85/192 (44%), Gaps = 26/192 (13%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRD----LKTQGRLWEAARALA-CPPGSL 60 V++TG S GIG +A L+ + V T R K R E A A G++ Sbjct: 21 VIVTGASKGIGREMAYHLSKMGAH---VVLTARSEEGLQKVVSRCLELGAASAHYIAGTM 77 Query: 61 ETL----QLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGED--AVASVLDV 114 E + Q V+ K + G +D+L+ N L +D +V V++V Sbjct: 78 EDMTFAEQFIVKAGKLM---------GGLDMLILNHITQ--TSLSLFHDDIHSVRRVMEV 126 Query: 115 NVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLL 174 N + V M A LP M ++ +G + V S+ G M P Y ASKFAL+G ++ L Sbjct: 127 NFLSYVVMSTAALP-MLKQSNGSIAVISSLAGKMTQPMIAPYSASKFALDGFFSTIRTEL 185 Query: 175 LPFGVHLSLIEC 186 V++S+ C Sbjct: 186 YITKVNVSITLC 197 >2B4Q-A nrPDB Length = 276 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 57/212 (26%), Positives = 85/212 (40%), Gaps = 20/212 (9%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 +A + L+TG S GIG +A L + +V+ RD EA A + Sbjct: 27 LAGRIALVTGGSRGIGQMIAQGLLEAGA---RVFICARDA-------EACADTATRLSAY 76 Query: 61 ETLQLDVRDSKSVAAARERVT-----EGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVN 115 Q D S A AR R+D+LV NAG LE+ V+ +N Sbjct: 77 GDCQAIPADLSSEAGARRLAQALGELSARLDILVNNAGTSWGAALESYPVSGWEKVMQLN 136 Query: 116 VVGTVRMLQAFLPDMKRRGS----GRVLVTGSVGGLMGLPFND-VYCASKFALEGLCESL 170 V +Q LP ++R S RV+ GSV G+ + Y SK AL L L Sbjct: 137 VTSVFSCIQQLLPLLRRSASAENPARVINIGSVAGISAMGEQAYAYGPSKAALHQLSRML 196 Query: 171 AVLLLPFGVHLSLIECGPVHTAFMEKVLGSPE 202 A L+ +++++I G + + P+ Sbjct: 197 AKELVGEHINVNVIAPGRFPSRMTRHIANDPQ 228 >4CQL-A nrPDB Length = 261 Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 56/206 (27%), Positives = 92/206 (44%), Gaps = 8/206 (3%) Query: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPP-GSLETLQL 65 L+TG SGIG ++VRLA + + + RL + PP G+ Q Sbjct: 15 LVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQA 74 Query: 66 DVRDSKSVAAARERVTEGRV---DVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 DV ++++ E+V V+V AG+ L + ED V+ VN+ GT + Sbjct: 75 DVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLV 134 Query: 123 LQAFLPDMKRRGS-GRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 QA + G G ++ S+ G +G Y ASK + GL ++ A L G+ Sbjct: 135 TQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRC 194 Query: 182 SLIECGPVHTAFMEKVLGSPEEVLDR 207 + + G + T +KV P++V+D+ Sbjct: 195 NSVLPGFIATPMTQKV---PQKVVDK 217 >3DWF-A nrPDB Length = 276 Score = 45.4 bits (106), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 57/188 (30%), Positives = 82/188 (43%), Gaps = 18/188 (9%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 V++TG S GIG +A LA + V T R + ++ AR L S + Sbjct: 14 VIVTGASKGIGREIAYHLAKMGAH---VVVTARSKEALQKV--VARCLELGAASAHYIAG 68 Query: 66 DVRDSKSVAAARERVTE-----GRVDVLVCNAGLGLLGPLEAL-GE-DAVASVLDVNVVG 118 + D + A E V E G +D+L+ N L L GE D V ++VN Sbjct: 69 SMED---MTFAEEFVAEAGNLMGGLDMLILNHVL--YNRLTFFHGEIDNVRKSMEVNFHS 123 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 V + A +P M + G + V SV G + P Y ASKFAL+G +L L Sbjct: 124 FVVLSVAAMP-MLMQSQGSIAVVSSVAGKITYPLIAPYSASKFALDGFFSTLRSEFLVNK 182 Query: 179 VHLSLIEC 186 V++S+ C Sbjct: 183 VNVSITLC 190 >2C07-A nrPDB Length = 285 Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 53/220 (24%), Positives = 87/220 (39%), Gaps = 24/220 (10%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 V L+TG GIG +A LA S V R K+ + + ++ Sbjct: 46 VALVTGAGRGIGREIAKMLAKSVSH---VICISRTQKSCDSVVDEIKSFGYESSGYAG-- 100 Query: 65 LDVRDSKSVAAARERV-TEGR-VDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 DV + ++ ++ TE + VD+LV NAG+ + D VL N+ + Sbjct: 101 -DVSKKEEISEVINKILTEHKNVDILVNNAGITRDNLFLRMKNDEWEDVLRTNLNSLFYI 159 Query: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLS 182 Q M GR++ S+ GL G Y +SK + G +SLA L + ++ Sbjct: 160 TQPISKRMINNRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKELASRNITVN 219 Query: 183 LIECGPVHTAFMEKV----------------LGSPEEVLD 206 I G + + +K+ +G+PEEV + Sbjct: 220 AIAPGFISSDMTDKISEQIKKNIISNIPAGRMGTPEEVAN 259 >1YXM-A nrPDB Length = 303 Score = 45.1 bits (105), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 54/227 (23%), Positives = 91/227 (40%), Gaps = 34/227 (14%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKT-----QGRLWEAARALACPPGS 59 V ++TG ++GIG + L S L LK+ Q L +A P Sbjct: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIP--- 76 Query: 60 LETLQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVV 117 +Q ++R+ + V + T G+++ LV N G L P E + +VL+ N+ Sbjct: 77 ---IQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133 Query: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 GT M +A + G + V V G P A++ + L +SLA+ Sbjct: 134 GTFYMCKAVYSSWMKEHGGSI-VNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACS 192 Query: 178 GVHLSLIECGPVHT------------AFME--------KVLGSPEEV 204 G+ ++ + G +++ +F E K +G PEEV Sbjct: 193 GIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEV 239 >2FWM-X nrPDB Length = 250 Score = 44.3 bits (103), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 39/137 (28%), Positives = 63/137 (45%), Gaps = 5/137 (3%) Query: 65 LDVRDSKSVAAARERV---TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 +DV D+ VA +R+ TE R+D LV AG+ +G + L ++ VNV G Sbjct: 53 MDVADAAQVAQVCQRLLAETE-RLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 111 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 + Q + +R+ G ++ S Y ASK AL+ L S+ + L GV Sbjct: 112 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 171 Query: 182 SLIECGPVHTAFMEKVL 198 +++ G T M++ L Sbjct: 172 NVVSPGSTDTD-MQRTL 187 >3ZV3-A nrPDB Length = 281 Score = 44.3 bits (103), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 56/180 (31%), Positives = 81/180 (45%), Gaps = 19/180 (10%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 V LITG +SG+G L R ++ ++ A L + R E A G+ + Sbjct: 7 VALITGGASGLGRALVDRFVAEGAR----VAVLDKSAERLRELEVAHG-----GNAVGVV 57 Query: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLG-PLEALGEDAVASVLD----VNVV 117 DVR + A ER G++D L+ NAG+ L L ED + + D VNV Sbjct: 58 GDVRSLQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDIFHVNVK 117 Query: 118 GTVRMLQAFLPDM-KRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLP 176 G + ++A LP + RGS V+ T S G +Y A+K A+ GL +A L P Sbjct: 118 GYIHAVKACLPALVSSRGS--VVFTISNAGFYPNGGGPLYTATKHAVVGLVRQMAFELAP 175 >5IZ4-A nrPDB Length = 271 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 75/281 (26%), Positives = 114/281 (40%), Gaps = 50/281 (17%) Query: 5 VVLITGCSSGIGLHLAVRLA-------------SDPSQSFKVYATLRDLKTQGRLWEAAR 51 V +ITG +SGIG A+R A S + V A RD Q +++A Sbjct: 16 VCVITGSASGIGAATALRFAQAGWSVAIGNFDDSTRDAASTVEALCRDAGAQTLIFDA-- 73 Query: 52 ALACPPGSLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEA---LGEDAV 108 G D R + + A+R + R+D L+ AG + P A + + Sbjct: 74 ----DVGK----DADCRHAVDMVASRWQ----RIDALINCAGTTRVIPHNAFDQIDDFEF 121 Query: 109 ASVLDVNVVGTVRMLQAFLPDMKRRGSG----RVLVTGSVGGLMGLPFNDVYCASKFALE 164 V VN++G +M +A +P ++ S V+ S+ GL G + Y ASK A+ Sbjct: 122 ERVYRVNLIGLYQMTRAAVPLLRESASATRSTSVVNVSSLAGLNGTGSSIAYAASKGAVN 181 Query: 165 GLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSK 224 L SLA L P + ++ + G V + +VL D + + S Sbjct: 182 TLTLSLARNLAPH-IRVNALAPGMVDDGLLLRVL----------DAAAYDGVLSRMTESA 230 Query: 225 QVFREAAQNPEEVAEV--FLTALRAPKPTLRYFTTERFLPL 263 + R P E+AE+ FLTA AP T + E L L Sbjct: 231 PLKR--VSRPAEIAELAWFLTA-HAPAITGQVIAAENGLLL 268 >1H5Q-A nrPDB Length = 265 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 50/205 (24%), Positives = 88/205 (42%), Gaps = 20/205 (9%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPG-SLETLQ 64 +++TG + GIGL +A+ + +Y + D E + G + Q Sbjct: 17 IIVTGGNRGIGLAFTRAVAAAGANVAVIYRSAADAV------EVTEKVGKEFGVKTKAYQ 70 Query: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 DV ++ V +++ G + L+ NAG+ ++ P L + A V DVNV G Sbjct: 71 CDVSNTDIVTKTIQQIDADLGPISGLIANAGVSVVKPATELTHEDFAFVYDVNVFGVFNT 130 Query: 123 LQAFLP-DMKRRGSGRVLVTGSV-------GGLMGLPFNDVYCASKFALEGLCESLAVLL 174 +A ++++ G ++VT S+ L G Y +SK A L + LA Sbjct: 131 CRAVAKLWLQKQQKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSSKAACSNLVKGLAAEW 190 Query: 175 LPFGVHLSLIECGPVH---TAFMEK 196 G+ ++ + G V+ TA M+K Sbjct: 191 ASAGIRVNALSPGYVNTDQTAHMDK 215 >1BDB-A nrPDB Length = 277 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 58/195 (29%), Positives = 93/195 (47%), Gaps = 22/195 (11%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPG-SLETLQ 64 VLITG +SG+G L R ++ ++ A L K+ RL E L G ++ + Sbjct: 8 VLITGGASGLGRALVDRFVAEGAK----VAVLD--KSAERLAE----LETDHGDNVLGIV 57 Query: 65 LDVR--DSKSVAAARERVTEGRVDVLVCNAGLGLLG------PLEALGEDAVASVLDVNV 116 DVR + + AA+R G++D L+ NAG+ P E+L + A V +NV Sbjct: 58 GDVRSLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESL-DAAFDEVFHINV 116 Query: 117 VGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLP 176 G + ++A LP + G V+ T S G +Y A+K A+ GL LA L P Sbjct: 117 KGYIHAVKACLPALVAS-RGNVIFTISNAGFYPNGGGPLYTAAKHAIVGLVRELAFELAP 175 Query: 177 FGVHLSLIECGPVHT 191 + V ++ + G +++ Sbjct: 176 Y-VRVNGVGSGGINS 189 >4KMS-A nrPDB Length = 249 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 48/206 (23%), Positives = 88/206 (42%), Gaps = 16/206 (7%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 + ++TG + GIG A+ L ++ V A ++AA+ + G ++T Sbjct: 12 IAIVTGGTRGIGKATALEL---KNKGLTVVANFFSN------YDAAKEMEEKYG-IKTKC 61 Query: 65 LDVRDSKSVAAARERVTE---GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 +V D + A + + E V +LV NAG+ L + V++VN+ Sbjct: 62 WNVADFEECRQAVKEIEEEFKKPVSILVNNAGITKDKMLHRMSHQDWNDVINVNLNSCFN 121 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 M + + M+ + GR++ S+ G Y A+K + G ++LA + + Sbjct: 122 MSSSVMEQMRNQDYGRIVNISSINAQAGQVGQTNYSAAKAGIIGFTKALARETASKNITV 181 Query: 182 SLIECGPVHTAFMEKVLGSPEEVLDR 207 + I G + T E V PE+VL + Sbjct: 182 NCIAPGYIAT---EMVGAVPEDVLAK 204 >4Z9Y-A nrPDB Length = 253 Score = 42.0 bits (97), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 54/213 (25%), Positives = 91/213 (42%), Gaps = 22/213 (10%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYA-----TLRDLKTQGRLWEAARA-LACPPG 58 V LITGC +G+G +A+ LA V T+ + GR + + A ++ G Sbjct: 12 VALITGCDTGLGQGMAIGLAQAGCDIVGVNIVEPKDTIEKVTALGRRFLSLTADMSNVSG 71 Query: 59 SLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 E ++ K+VA G VD+LV NAG+ E V+++N+ Sbjct: 72 HAELVE------KAVAEF------GHVDILVNNAGIIRREDAIEFSEKNWDDVMNLNIKS 119 Query: 119 TVRMLQAFLPDMKRRGS-GRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 M Q ++G G+++ S+ G Y ASK A+ G+ +A Sbjct: 120 VFFMSQTVARQFIKQGKGGKIINIASMLSFQGGIRVPSYTASKSAVMGVTRLMANEWAKH 179 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPE---EVLDR 207 G++++ I G + T +++ E E+LDR Sbjct: 180 GINVNAIAPGYMATNNTQQLRADEERSKEILDR 212 >4DRY-A nrPDB Length = 281 Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 44/139 (31%), Positives = 63/139 (45%), Gaps = 25/139 (17%) Query: 44 GRLWEAARALACPPGSLETLQLDVRDSKSVAA--ARERVTEGRVDVLVCNAGLGLLG-PL 100 GR RA+ C DV D VAA A R R+D+LV NAG + PL Sbjct: 79 GRTGNIVRAVVC----------DVGDPDQVAALFAAVRAEFARLDLLVNNAGSNVPPVPL 128 Query: 101 EALGEDAVASVLDVNVVGTV-------RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFN 153 E + + ++ N+ G RM++A P RG GR++ GS+ P + Sbjct: 129 EEVTFEQWNGIVAANLTGAFLCTQHAFRMMKAQTP----RG-GRIINNGSISAQTPRPNS 183 Query: 154 DVYCASKFALEGLCESLAV 172 Y A+K A+ GL +S A+ Sbjct: 184 APYTATKHAITGLTKSTAL 202 >2HRB-A nrPDB Length = 274 Score = 41.2 bits (95), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 52/173 (30%), Positives = 69/173 (39%), Gaps = 9/173 (5%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 V L+TG + GIGL +A L S V T RD+ R A + L S Q Sbjct: 4 VALVTGANRGIGLAIARELCRQFSGD--VVLTARDV---ARGQAAVQQLQAEGLSPRFHQ 58 Query: 65 LDVRDSKSVAAARE--RVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 LD+ D +S+ A R+ R G ++VLV NA + + L N T M Sbjct: 59 LDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNM 118 Query: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLL 175 LP MK GRV+ S+ L +F E L E V L+ Sbjct: 119 CNELLPIMK--PHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLM 169 >1E3W-A nrPDB Length = 261 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 55/198 (27%), Positives = 85/198 (42%), Gaps = 25/198 (12%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 V +ITG +SG+GL A RL + A L D+ EA + G+ Sbjct: 12 VAVITGGASGLGLSTAKRLVGQGAT-----AVLLDVPNSEGETEAKKL----GGNCIFAP 62 Query: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVAS------VLDVNV 116 +V K V AA E GR+DV V AG+ + ++ V + V++VN+ Sbjct: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 Query: 117 VGT---VRMLQAFL----PDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCES 169 +GT +R++ + PD + G ++ T SV G Y ASK + G+ Sbjct: 123 IGTFNVIRLVAGVMGQNEPDQGGQ-RGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 181 Query: 170 LAVLLLPFGVHLSLIECG 187 +A L P G+ + I G Sbjct: 182 IARDLAPIGIRVVTIAPG 199 >1W73-A nrPDB Length = 302 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 31/135 (22%), Positives = 62/135 (45%), Gaps = 3/135 (2%) Query: 60 LETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVV 117 + +Q DVRD V + + G ++++ NA + P E L +A ++ D+ + Sbjct: 78 VHAIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLN 137 Query: 118 GTVRM-LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLP 176 GT + L+ +K + L ++ G F ++K +E + +SLA Sbjct: 138 GTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGK 197 Query: 177 FGVHLSLIECGPVHT 191 +G+ ++I+ GP+ T Sbjct: 198 YGMRFNVIQPGPIKT 212 >5OJG-A nrPDB Length = 260 Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust. Identities = 50/217 (23%), Positives = 86/217 (39%), Gaps = 21/217 (9%) Query: 5 VVLITGCSSGIGLHLAVRLASDPS-------QSFKVYATLRDLKTQGRLWEAARALACPP 57 V ++T + GIGL +A RL + + V + LK +G A A Sbjct: 12 VAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIAGHIAS 71 Query: 58 GSLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLG-LLGPLEALGEDAVASVLDVNV 116 + +D K G++++LV N G+ G + + + + +VNV Sbjct: 72 TDDQKKLVDFTLQKF----------GKINILVNNHGINPAFGHILEVSDQVWDKLFEVNV 121 Query: 117 VGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLP 176 +M + P + + G G ++ S P Y +K L GL +LA+ L Sbjct: 122 KAGFQMTKLVHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAK 181 Query: 177 FGVHLSLIECGPVHTAFMEKVL--GSPEEVLDRTDIH 211 + ++ I G + T M +VL G + + TDI Sbjct: 182 DNIRVNGIAPGVIKTK-MSQVLWDGGEDAEKELTDIQ 217 >3R3S-A nrPDB Length = 294 Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust. Identities = 49/193 (25%), Positives = 79/193 (40%), Gaps = 13/193 (6%) Query: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQ---GRLWEAARALACPPGSLETL 63 L+TG SGIG A+ A + + Y + Q + E R PG L Sbjct: 53 LVTGGDSGIGRAAAIAYAREGADVAINYLPAEEEDAQQVKALIEECGRKAVLLPGDLS-- 110 Query: 64 QLDVRDSKS-VAAARERVTEGRVDVLVCNAGLGLLGP-LEALGEDAVASVLDVNVVGTVR 121 D ++S V ARE + G +D+L AG P ++ L + VNV Sbjct: 111 --DESFARSLVHKAREAL--GGLDILALVAGKQTAIPEIKDLTSEQFQQTFAVNVFALFW 166 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 + Q +P + + S ++ T S+ P Y A+K A+ LA + G+ + Sbjct: 167 ITQEAIPLLPKGAS--IITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRV 224 Query: 182 SLIECGPVHTAFM 194 +++ GP+ TA Sbjct: 225 NIVAPGPIWTALQ 237 >5JY1-A nrPDB Length = 274 Score = 37.4 bits (85), Expect = 0.010, Method: Compositional matrix adjust. Identities = 36/145 (24%), Positives = 62/145 (42%), Gaps = 7/145 (4%) Query: 63 LQLDVRDSKSVAAARERVTE--GRVDVLVCNAGL---GLLGPLEALGEDAVASVLDVNVV 117 ++ DV S+ AA E G +D+LV NA + +L LE ++ + L ++ Sbjct: 68 VKTDVTSKASIEAAVRSAVEQFGSLDILVNNAFVPTPNVL--LEEKTDEMLEQTLTTSLW 125 Query: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 T ++A M+ R GR++ S+ G + Y +K + GL S A F Sbjct: 126 ATWWAMRAAFVPMRERRWGRIVNFYSIDTETGAWLHGDYNTAKAGIVGLTRSAASEWGRF 185 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPE 202 + ++ I + F E +PE Sbjct: 186 NITVNAIAPTAMGATFFELAAKNPE 210 >3KZV-A nrPDB Length = 254 Score = 37.0 bits (84), Expect = 0.012, Method: Compositional matrix adjust. Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 6/93 (6%) Query: 82 EGRVDVLVCNAGLGLLGPLEALGE---DAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRV 138 G++D LV NAG+ L P++ + E +A + D+N V ++ LP++K+ +G V Sbjct: 76 HGKIDSLVANAGV--LEPVQNVNEIDVNAWKKLYDINFFSIVSLVGIALPELKKT-NGNV 132 Query: 139 LVTGSVGGLMGLPFNDVYCASKFALEGLCESLA 171 + S M Y +SK AL +LA Sbjct: 133 VFVSSDACNMYFSSWGAYGSSKAALNHFAMTLA 165 >5L51-A nrPDB Length = 324 Score = 36.6 bits (83), Expect = 0.015, Method: Compositional matrix adjust. Identities = 35/100 (35%), Positives = 48/100 (48%), Gaps = 13/100 (13%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGS--- 59 + ++TG + GIG + +LA S+ V RD K R EA L GS Sbjct: 15 KRYAVVTGANKGIGFEICKQLA---SKGITVILASRDEK---RGIEARERLIKELGSEFG 68 Query: 60 --LETLQLDVRDSKSVAAARE--RVTEGRVDVLVCNAGLG 95 + + QLDV D SVAA + + G +D+LV NAGL Sbjct: 69 DYVVSQQLDVADPASVAALVDFIKTKFGSLDILVNNAGLN 108 >4OYR-A nrPDB Length = 289 Score = 36.2 bits (82), Expect = 0.020, Method: Compositional matrix adjust. Identities = 39/154 (25%), Positives = 69/154 (44%), Gaps = 15/154 (9%) Query: 57 PGSLETLQLDVRDSKSVAAARERVTE-----GRVDVLVCN------AGLGLLGPLEALGE 105 P L+LDV++ + +A+ RVTE ++D +V + G+G+ +A Sbjct: 75 PAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYA 134 Query: 106 DAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEG 165 D V+ + ++ M +A LP M GS +V +P + +K ALE Sbjct: 135 D-VSKGIHISAYSYASMAKALLPIMNPGGS---IVGMDFDPSRAMPAYNWMTVAKSALES 190 Query: 166 LCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLG 199 + +A +GV +L+ GP+ T M ++G Sbjct: 191 VNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVG 224 >1DOH-A nrPDB Length = 283 Score = 36.2 bits (82), Expect = 0.020, Method: Compositional matrix adjust. Identities = 39/196 (19%), Positives = 83/196 (42%), Gaps = 10/196 (5%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQ--GRLWEAARALACPPGSLET 62 V L+TG GIG +A+ L + YA + + + + AC ++ Sbjct: 31 VALVTGAGRGIGREMAMELGRRGCKVIVNYANSTESAEEVVAAIKKNGSDAACVKANVGV 90 Query: 63 LQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 ++ VR + G++D++ N+G+ G ++ + + V +N G + Sbjct: 91 VEDIVRMFEEAVK-----IFGKLDIVCSNSGVVSFGHVKDVTPEEFDRVFTINTRGQFFV 145 Query: 123 LQAFLPDMKRRGSGRVLVTGSVGG-LMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 + ++ GR+++ GS+ G +P + VY SK A+E +A+ + + + Sbjct: 146 AREAYKHLEI--GGRLILMGSITGQAKAVPKHAVYSGSKGAIETFARCMAIDMADKKITV 203 Query: 182 SLIECGPVHTAFMEKV 197 +++ G + T V Sbjct: 204 NVVAPGGIKTDMYHAV 219 >5WQO-A nrPDB Length = 234 Score = 35.4 bits (80), Expect = 0.031, Method: Compositional matrix adjust. Identities = 56/194 (28%), Positives = 80/194 (41%), Gaps = 19/194 (9%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGS-LETLQ 64 VLI G S GIGL LA +Q F V + QG +ALA G L+ + Sbjct: 9 VLIVGASRGIGLGLADAFLQRGAQVFAVAR-----RPQGS--PGLQALAERAGERLQAVT 61 Query: 65 LDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEA----LGEDAVASVLDVNVVGTV 120 D+ E + E R+D L+ NA G+ GP + + + A + N + + Sbjct: 62 GDLNQHDCAERIGEMLGERRIDRLIVNA--GIYGPQQQDVAEIDAEQTAQLFLTNAIAPL 119 Query: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFN-DVYCASKFALEGLCESLAVLL--LPF 177 R+ +A + R G + + +GL +Y ASK AL L S LPF Sbjct: 120 RLARALSGRVSRGGVVAFMSSQMASLALGLSATMPLYGASKAALNSLVRSWEGEFEELPF 179 Query: 178 GVHLSLIECGPVHT 191 L L+ G V T Sbjct: 180 --SLLLLHPGWVRT 191 >4AVY-A nrPDB Length = 242 Score = 35.4 bits (80), Expect = 0.033, Method: Compositional matrix adjust. Identities = 52/188 (27%), Positives = 81/188 (43%), Gaps = 21/188 (11%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 VL+TG SSGIG +A++ A ++ + G + A P + +L Sbjct: 14 VLVTGGSSGIGAAIAMQFAELGAEVVAL----------GLDADGVHAPRHP--RIRREEL 61 Query: 66 DVRDSKSVAAARERVTEG--RVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRML 123 D+ DS+ + +R+ E R+DVLV NAG+ E VL +N+ + Sbjct: 62 DITDSQRL----QRLFEALPRLDVLVNNAGISR--DREEYDLATFERVLRLNLSAAMLAS 115 Query: 124 QAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSL 183 Q P + +RG G +L S+ G Y ASK A+ L SLA + ++ Sbjct: 116 QLARPLLAQRG-GSILNIASMYSTFGSADRPAYSASKGAIVQLTRSLACEYAAERIRVNA 174 Query: 184 IECGPVHT 191 I G + T Sbjct: 175 IAPGWIDT 182 >1FJH-A nrPDB Length = 257 Score = 35.4 bits (80), Expect = 0.034, Method: Compositional matrix adjust. Identities = 35/146 (23%), Positives = 63/146 (43%), Gaps = 37/146 (25%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETL 63 ++++I+GC++GIG AT + L+ G + + Sbjct: 2 SIIVISGCATGIG-----------------AATRKVLEAAGH---------------QIV 29 Query: 64 QLDVRDSKSVA--AARERVTEGRVDVLV-CNAGLGLLGPLEALG--EDAVASVLDVNVVG 118 +D+RD++ +A + E + DVL C+ G+ L LG + +V+ VN G Sbjct: 30 GIDIRDAEVIADLSTAEGRKQAIADVLAKCSKGMDGLVLCAGLGPQTKVLGNVVSVNYFG 89 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSV 144 ++ AFLP +K+ +V SV Sbjct: 90 ATELMDAFLPALKKGHQPAAVVISSV 115 >2P91-A nrPDB Length = 285 Score = 35.0 bits (79), Expect = 0.047, Method: Compositional matrix adjust. Identities = 45/193 (23%), Positives = 82/193 (42%), Gaps = 16/193 (8%) Query: 7 LITGCSS--GIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 LITG ++ I +A + +Q YAT K + R+ E A+ GS ++ Sbjct: 25 LITGVANERSIAYGIAKSFHREGAQLAFTYATP---KLEKRVREIAKGF----GSDLVVK 77 Query: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLG----LLGPLEALGEDAVASVLDVNVVG 118 DV + + ++ + E G +D++V + G + + +D++V Sbjct: 78 CDVSLDEDIKNLKKFLEENWGSLDIIVHSIAYAPKEEFKGGVIDTSREGFKIAMDISVYS 137 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 + + + LP M+ R +G ++ G +P +V +K ALE LA + G Sbjct: 138 LIALTRELLPLMEGR-NGAIVTLSYYGAEKVVPHYNVMGIAKAALESTVRYLAYDIAKHG 196 Query: 179 VHLSLIECGPVHT 191 ++ I GPV T Sbjct: 197 HRINAISAGPVKT 209 >5LCX-A nrPDB Length = 316 Score = 35.0 bits (79), Expect = 0.048, Method: Compositional matrix adjust. Identities = 41/145 (28%), Positives = 66/145 (45%), Gaps = 24/145 (16%) Query: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRD----LKTQGRLWEAARALACPPGSLET 62 L+TG + GIG + +LA + V T R+ L+ + +L + L L Sbjct: 11 LVTGANKGIGFEICRQLA---EKGIIVILTSRNEKRGLEARQKL---LKELNVSENRLVF 64 Query: 63 LQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 QLDV D SVAA + G++D+LV NAG + +E +G+ SV + + Sbjct: 65 HQLDVTDLASVAAVAVFIKSKFGKLDILVNNAG---VSGVEMVGD---VSVFNEYIEADF 118 Query: 121 RMLQAF------LPDMKRRGSGRVL 139 + LQA P K + +G ++ Sbjct: 119 KALQALEAGAKEEPPFKPKANGEMI 143 >4GKB-A nrPDB Length = 258 Score = 34.7 bits (78), Expect = 0.053, Method: Compositional matrix adjust. Identities = 56/201 (27%), Positives = 89/201 (44%), Gaps = 11/201 (5%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 VV++TG +SGIG +++RLA + + + G + ALA L Sbjct: 9 VVIVTGGASGIGGAISMRLAEERA----IPVVFARHAPDGAFLD---ALAQRQPRATYLP 61 Query: 65 LDVRDSKSV--AAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 ++++D A A+ T GR+D LV NAG+ L+A G DA + L+ N++ M Sbjct: 62 VELQDDAQCRDAVAQTIATFGRLDGLVNNAGVNDGIGLDA-GRDAFVASLERNLIHYYAM 120 Query: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLS 182 +P +K G ++ S + G YCASK A L AV L GV ++ Sbjct: 121 AHYCVPHLK-ATRGAIVNISSKTAVTGQGNTSGYCASKGAQLALTREWAVALREHGVRVN 179 Query: 183 LIECGPVHTAFMEKVLGSPEE 203 + V T + + E+ Sbjct: 180 AVIPAEVMTPLYRNWIATFED 200 >3GRK-A nrPDB Length = 293 Score = 33.1 bits (74), Expect = 0.16, Method: Compositional matrix adjust. Identities = 39/147 (26%), Positives = 59/147 (40%), Gaps = 12/147 (8%) Query: 53 LACPPGSLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVAS 110 LA G+ DV D+ S+ A E + + G++D LV G L D Sbjct: 76 LAEELGAFVAGHCDVADAASIDAVFETLEKKWGKLDFLVHAIGFSDKDELTGRYIDTS-- 133 Query: 111 VLDVNVVGTVRMLQAFLPDMKRRGS------GRVLVTGSVGGLMGLPFNDVYCASKFALE 164 + N T+ + L + RR G +L G +P +V +K ALE Sbjct: 134 --EANFTNTMLISVYSLTAVSRRAEKLMADGGSILTLTYYGAEKVMPNYNVMGVAKAALE 191 Query: 165 GLCESLAVLLLPFGVHLSLIECGPVHT 191 + LAV L P + ++ I GP+ T Sbjct: 192 ASVKYLAVDLGPQNIRVNAISAGPIKT 218 >4DA9-A nrPDB Length = 280 Score = 33.1 bits (74), Expect = 0.19, Method: Compositional matrix adjust. Identities = 56/223 (25%), Positives = 87/223 (39%), Gaps = 34/223 (15%) Query: 2 ARTVVLITGCS-----------SGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAA 50 AR V ++TG + G +A+ D V A L L A Sbjct: 28 ARPVAIVTGGRRGIGLGIARALAASGFDIAITGIGDAEGVAPVIAELSGL--------GA 79 Query: 51 RALACPPGSLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLL--GPLEALGED 106 R + L+ D+ D S A + V GR+D LV NAG+ + L + Sbjct: 80 RVI--------FLRADLADLSSHQATVDAVVAEFGRIDCLVNNAGIASIVRDDFLDLKPE 131 Query: 107 AVASVLDVNVVGTVRMLQAFLPDM---KRRGSGRVLVTGSVGGLMGLPFNDVYCASKFAL 163 +++ VN+ GTV QA L M R S ++ SV +M P YC SK L Sbjct: 132 NFDTIVGVNLRGTVFFTQAVLKAMLASDARASRSIINITSVSAVMTSPERLDYCMSKAGL 191 Query: 164 EGLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLD 206 + LA+ L G+ + + G + + V G + +++ Sbjct: 192 AAFSQGLALRLAETGIAVFEVRPGIIRSDMTAAVSGKYDGLIE 234 >2NTV-A nrPDB Length = 268 Score = 33.1 bits (74), Expect = 0.19, Method: Compositional matrix adjust. Identities = 38/148 (25%), Positives = 68/148 (45%), Gaps = 15/148 (10%) Query: 63 LQLDVRDSKSVAAARERVT----EG-RVDVLVCN------AGLGLLGPLEALGEDAVASV 111 ++LDV++ + +A ERVT EG ++D +V + G+G +A ED V+ Sbjct: 60 IELDVQNEEHLATLAERVTAEIGEGNKLDGVVHSIGFMPQTGMGTNQFFDAPYED-VSKG 118 Query: 112 LDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLA 171 + ++ + +A L M GS +V +P + +K ALE + +A Sbjct: 119 IHISTYSYASLAKALLLIMNSGGS---IVGMDFDPTRAMPAYNWMTVAKSALESVNRFVA 175 Query: 172 VLLLPFGVHLSLIECGPVHTAFMEKVLG 199 +GV +L+ GP+ T M ++G Sbjct: 176 REAGKYGVRSNLVAAGPIRTLAMSAIVG 203 >1AHH-A nrPDB Length = 255 Score = 32.7 bits (73), Expect = 0.19, Method: Compositional matrix adjust. Identities = 36/150 (24%), Positives = 62/150 (41%), Gaps = 29/150 (19%) Query: 7 LITGCSSGIGLHLAVRLAS----------DPSQSFKVYATLRDLKTQGRLWEAARALACP 56 +ITG +GIG +A+ A+ + + V ++ L Q A AC Sbjct: 15 IITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQ--------AFAC- 65 Query: 57 PGSLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDV 114 + D+ + ++A + G+VD+LV NAG G P + D ++ Sbjct: 66 -------RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD-FRRAYEL 117 Query: 115 NVVGTVRMLQAFLPDMKRRGSGRVLVTGSV 144 NV + Q P+M++ G G +L S+ Sbjct: 118 NVFSFFHLSQLVAPEMEKNGGGVILTITSM 147 >1HXH-A nrPDB Length = 253 Score = 32.7 bits (73), Expect = 0.22, Method: Compositional matrix adjust. Identities = 58/222 (26%), Positives = 93/222 (41%), Gaps = 21/222 (9%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET-L 63 V L+TG +SG+GL + L + ++ D+ A + LA G + Sbjct: 8 VALVTGGASGVGLEVVKLLLGEGAK-----VAFSDINE-----AAGQQLAAELGERSMFV 57 Query: 64 QLDVR---DSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 + DV D V AA +R G ++VLV NAG+ L G +E + + +L +N Sbjct: 58 RHDVSSEADWTLVMAAVQRRL-GTLNVLVNNAGILLPGDMETGRLEDFSRLLKINTESVF 116 Query: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180 Q + MK G G ++ SV + + Y ASK A+ L + A+ G Sbjct: 117 IGCQQGIAAMKETG-GSIINMASVSSWLPIEQYAGYSASKAAVSALTRAAALSCRKQGYA 175 Query: 181 LSLIECGP--VHTAFMEKVL---GSPEEVLDRTDIHTFHRFY 217 + + P ++T M+ L S E VL ++ R Y Sbjct: 176 IRVNSIHPDGIYTPMMQASLPKGVSKEMVLHDPKLNRAGRAY 217 >5TF4-A nrPDB Length = 274 Score = 32.7 bits (73), Expect = 0.22, Method: Compositional matrix adjust. Identities = 35/132 (26%), Positives = 56/132 (42%), Gaps = 8/132 (6%) Query: 66 DVRDSKSVAAARERVTE--GRVDVLVCNAGLG----LLGPLEALGEDAVASVLDVNVVGT 119 DV DS S+ A + + G++D LV G L G + E ++++V Sbjct: 70 DVSDSASIDAVFNTIEKKWGKLDFLVHAIGFSDKEELSGRYVDISESNFMMTMNISVYSL 129 Query: 120 VRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGV 179 + + M GS +L G +P +V +K ALE + LAV L P + Sbjct: 130 TALTKRAEKLMSDGGS--ILTLTYYGAEKVVPNYNVMGVAKAALEASVKYLAVDLGPKHI 187 Query: 180 HLSLIECGPVHT 191 ++ I GP+ T Sbjct: 188 RVNAISAGPIKT 199 >5KOI-A nrPDB Length = 293 Score = 32.7 bits (73), Expect = 0.22, Method: Compositional matrix adjust. Identities = 41/148 (27%), Positives = 59/148 (39%), Gaps = 9/148 (6%) Query: 51 RALACPPGSLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAV 108 + LA GS L DV D +V A E + + G +D LV G L+ D Sbjct: 71 KPLAEQVGSDFVLPCDVEDIATVDAVFEEIEKKWGGLDFLVHAIGFSDKTELKGRYADVT 130 Query: 109 -----ASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFAL 163 + + ++ + Q MK GS L G G +P +V +K AL Sbjct: 131 TRENFSRTMVISAYSFTEVAQRAEKLMKDGGSILTLTYG--GSTRTIPNYNVMGVAKAAL 188 Query: 164 EGLCESLAVLLLPFGVHLSLIECGPVHT 191 E + LA P G+ ++ I GPV T Sbjct: 189 EAMVRYLAADYGPQGIRVNAISAGPVRT 216 >1MG5-A nrPDB Length = 255 Score = 32.7 bits (73), Expect = 0.22, Method: Compositional matrix adjust. Identities = 33/115 (28%), Positives = 47/115 (40%), Gaps = 11/115 (9%) Query: 85 VDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLP--DMKRRGSGRVLVT- 141 VDVL+ AG+ L + + + VN G V A L D ++ G G ++ Sbjct: 86 VDVLINGAGI--------LDDHQIERTIAVNYTGLVNTTTAILDFWDKRKGGPGGIICNI 137 Query: 142 GSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEK 196 GSV G + VY +K A+ SLA L GV + G T + K Sbjct: 138 GSVTGFNAIYQVPVYSGTKAAVVNFTSSLAKLAPITGVTAYTVNPGITRTTLVHK 192 >4HBG-A nrPDB Length = 286 Score = 32.3 bits (72), Expect = 0.28, Method: Compositional matrix adjust. Identities = 41/142 (28%), Positives = 64/142 (45%), Gaps = 22/142 (15%) Query: 85 VDVLVCNAGLGLLGPLEALGEDAVAS----VLDVNVVGTVRMLQAFLPDM---KRRG--- 134 V++L+ AGL E+L AS +++VN + V M + M +RR Sbjct: 114 VNLLINCAGLTQ----ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPEL 169 Query: 135 SGR-----VLVTGSV--GGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECG 187 SG+ ++ S+ G M +P VY ASK AL E LA + P + I G Sbjct: 170 SGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPG 229 Query: 188 PVH-TAFMEKVLGSPEEVLDRT 208 V T ++ + +E+L+RT Sbjct: 230 LVKGTDMIQNLPVEAKEMLERT 251 >1B15-A nrPDB Length = 254 Score = 32.0 bits (71), Expect = 0.41, Method: Compositional matrix adjust. Identities = 44/176 (25%), Positives = 64/176 (36%), Gaps = 42/176 (23%) Query: 85 VDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLP--DMKRRGSGRVLVT- 141 VD+L+ AG+ L + + + +N G V A L D ++ G G ++ Sbjct: 85 VDILINGAGI--------LDDHQIERTIAINFTGLVNTTTAILDFWDKRKGGPGGIIANI 136 Query: 142 GSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSP 201 SV G + VY ASK A+ SLA L GV I G T Sbjct: 137 CSVTGFNAIHQVPVYSASKAAVVSFTNSLAKLAPITGVTAYSINPGITRTPL-------- 188 Query: 202 EEVLDRTDIHTFHRFYQ--------YLAHSKQVFREAAQNPEEVAEVFLTALRAPK 249 +HTF+ + L+H Q + QN F+ A+ A K Sbjct: 189 --------VHTFNSWLDVEPRVAELLLSHPTQTSEQCGQN-------FVKAIEANK 229 >3O26-A nrPDB Length = 311 Score = 31.2 bits (69), Expect = 0.57, Method: Compositional matrix adjust. Identities = 50/201 (24%), Positives = 82/201 (40%), Gaps = 52/201 (25%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 62 R ++TG + GIG + +L+S+ V T RD+ T+G EA L + E Sbjct: 12 RRCAVVTGGNKGIGFEICKQLSSN---GIMVVLTCRDV-TKGH--EAVEKL--KNSNHEN 63 Query: 63 L---QLDVRD---SKSVAAARERVTEGRVDVLVCNAGLG--------LLGPLEALGEDA- 107 + QLDV D + S A + G++D+LV NAG+ + +GED+ Sbjct: 64 VVFHQLDVTDPIATMSSLADFIKTHFGKLDILVNNAGVAGFSVDADRFKAMISDIGEDSE 123 Query: 108 ---------------------VASVLDVNVVGTVRMLQAFLPDMKRRGSGRVL-VTGSVG 145 L +N G + + +P ++ S R++ V+ S G Sbjct: 124 ELVKIYEKPEAQELMSETYELAEECLKINYNGVKSVTEVLIPLLQLSDSPRIVNVSSSTG 183 Query: 146 GLMGLPFNDVYCASKFALEGL 166 L Y +++ ALE L Sbjct: 184 SLK-------YVSNETALEIL 197 >2YW9-A nrPDB Length = 261 Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust. Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 15/93 (16%) Query: 150 LPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTD 209 +P +V +K ALE LA L P GV ++ I GPV T + G Sbjct: 154 VPKYNVMAIAKAALEASVRYLAYELGPKGVRVNAISAGPVRTVAARSIPG---------- 203 Query: 210 IHTFHRFYQYLAHSKQVFREAAQNPEEVAEVFL 242 F + Y +A + + R Q EEV + L Sbjct: 204 ---FTKMYDRVAQTAPLRRNITQ--EEVGNLGL 231 >3NUT-A nrPDB Length = 251 Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust. Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 8/78 (10%) Query: 22 RLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAARERVT 81 R S P Q +V LR+ GRL ARA+ P ++ ++L RD A + Sbjct: 172 RSKSRPHQFTRVLEILREECEPGRLILFARAVTTPEQAISVVEL--RD------ATPEMA 223 Query: 82 EGRVDVLVCNAGLGLLGP 99 + R VLV NA +GP Sbjct: 224 DMRTVVLVGNAATRRVGP 241 >2DKN-A nrPDB Length = 255 Score = 29.6 bits (65), Expect = 1.7, Method: Compositional matrix adjust. Identities = 53/224 (23%), Positives = 78/224 (34%), Gaps = 53/224 (23%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETL 63 +V+ ITG +SGIG L LA + D++ PG ET Sbjct: 2 SVIAITGSASGIGAALKELLARAGHTVIGIDRGQADIEAD----------LSTPGGRET- 50 Query: 64 QLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRML 123 +VAA +R G +D LVC AG+G+ L V+ VN G +L Sbjct: 51 --------AVAAVLDRCG-GVLDGLVCCAGVGVTAANSGL-------VVAVNYFGVSALL 94 Query: 124 QAFLPDMKRRGSGRVLVTGSVG----GLMGLPFND----------------------VYC 157 + R ++ GS+ G LP + Y Sbjct: 95 DGLAEALSRGQQPAAVIVGSIAATQPGAAELPMVEAMLAGDEARAIELAEQQGQTHLAYA 154 Query: 158 ASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSP 201 SK+A+ L V GV L+++ G V T ++ P Sbjct: 155 GSKYAVTCLARRNVVDWAGRGVRLNVVAPGAVETPLLQASKADP 198 >4IIN-A nrPDB Length = 271 Score = 29.6 bits (65), Expect = 2.1, Method: Compositional matrix adjust. Identities = 42/169 (24%), Positives = 67/169 (39%), Gaps = 9/169 (5%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPG-SLETLQ 64 VLITG S GIG +A LA S KV+ R + + +A + G ++ Sbjct: 32 VLITGASKGIGAEIAKTLA---SMGLKVWINYR---SNAEVADALKNELEEKGYKAAVIK 85 Query: 65 LDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 D A + + ++G + LV NAG+ + + V+D N+ Sbjct: 86 FDAASESDFIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLTSAFIG 145 Query: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLA 171 + L M + G V+ S+ G G Y ASK + + +S A Sbjct: 146 CREALKVMSKSRFGSVVNVASIIGERGNMGQTNYSASKGGMIAMSKSFA 194 >4MWA-D nrPDB Length = 276 Score = 29.3 bits (64), Expect = 2.6, Method: Compositional matrix adjust. Identities = 17/45 (37%), Positives = 25/45 (55%), Gaps = 2/45 (4%) Query: 12 SSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACP 56 + GIG L + L++DP + KV L LK+ G AA ++CP Sbjct: 230 NKGIGNTLRISLSADPVEEVKVAREL--LKSFGLASNAATLISCP 272 >1NL7-A nrPDB Length = 392 Score = 29.3 bits (64), Expect = 2.6, Method: Compositional matrix adjust. Identities = 14/32 (43%), Positives = 20/32 (62%) Query: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPF 152 R+L L +MKRRG+ + L T +GG MG+ Sbjct: 356 RILNTLLFEMKRRGARKGLATLCIGGGMGVAM 387 >2PD3-A nrPDB Length = 275 Score = 28.9 bits (63), Expect = 3.1, Method: Compositional matrix adjust. Identities = 37/167 (22%), Positives = 64/167 (38%), Gaps = 8/167 (4%) Query: 31 FKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAARERVTE--GRVDVL 88 F ATL L + R +A S +LDV + + V + G +D + Sbjct: 29 FNQGATLAFTYLNESLEKRVRPIAQELNSPYVYELDVSKEEHFKSLYNSVKKDLGSLDFI 88 Query: 89 VCNAGLG----LLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSV 144 V + L G L + A + ++++V + + P + S VL + Sbjct: 89 VHSVAFAPKEALEGSLLETSKSAFNTAMEISVYSLIELTNTLKPLLNNGAS--VLTLSYL 146 Query: 145 GGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHT 191 G + +V +K ALE LAV L + ++ + GP+ T Sbjct: 147 GSTKYMAHYNVMGLAKAALESAVRYLAVDLGKHHIRVNALSAGPIRT 193 >5ORE-A nrPDB Length = 263 Score = 28.5 bits (62), Expect = 4.2, Method: Compositional matrix adjust. Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 13/60 (21%) Query: 65 LDVRDSKSVAAARERVTEGRVDVLVCNA-------------GLGLLGPLEALGEDAVASV 111 +D+++ KSV +T GR+D ++ NA G L+GPL + GE V +V Sbjct: 157 VDIKEYKSVEEHNLDLTSGRLDAVLANATVLAAAIEKPEMKGAKLVGPLFSGGEFGVVAV 216 >4TLZ-A nrPDB Length = 443 Score = 28.1 bits (61), Expect = 6.1, Method: Compositional matrix adjust. Identities = 17/38 (44%), Positives = 20/38 (52%) Query: 76 ARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLD 113 ARE + VDVLVC G + P + LGE A V D Sbjct: 347 AREESYDLDVDVLVCATGYDPMDPGDLLGELAEHCVQD 384 >2YNM-C nrPDB Length = 426 Score = 27.3 bits (59), Expect = 9.7, Method: Compositional matrix adjust. Identities = 16/45 (35%), Positives = 24/45 (53%), Gaps = 2/45 (4%) Query: 67 VRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASV 111 + + + V +RV E D++VC G+GL PLEA G S+ Sbjct: 346 IVEGQHVEKQLDRVREHHPDLVVC--GMGLANPLEAEGISTKWSI 388 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6CGE-A nrPDB 454 e-128 1A27-A nrPDB 385 e-107 4JRO-A nrPDB 247 4e-66 2C07-A nrPDB 245 2e-65 2PNF-A nrPDB 244 4e-65 2UVD-A nrPDB 243 8e-65 3OSU-A nrPDB 241 3e-64 2HQ1-A nrPDB 233 6e-62 3WOH-A nrPDB 232 1e-61 3RSH-A nrPDB 227 4e-60 2PH3-A nrPDB 226 9e-60 4RZH-A nrPDB 225 3e-59 3LYL-A nrPDB 224 3e-59 3FTP-A nrPDB 221 4e-58 4DMM-A nrPDB 221 5e-58 2CDH-G nrPDB 221 5e-58 4K6F-A nrPDB 220 6e-58 5CDY-A nrPDB 220 8e-58 1Q7C-A nrPDB 219 1e-57 4KMS-A nrPDB 219 2e-57 3F9I-A nrPDB 218 2e-57 5ITV-A nrPDB 218 2e-57 4NBV-A nrPDB 217 6e-57 3VZS-A nrPDB 216 2e-56 4NBT-A nrPDB 215 2e-56 3EZL-A nrPDB 214 4e-56 3OEC-A nrPDB 212 2e-55 3EMK-A nrPDB 212 2e-55 4M8S-A nrPDB 211 3e-55 4BO1-A nrPDB 211 4e-55 4DBZ-A nrPDB 210 6e-55 1AE1-A nrPDB 210 9e-55 4CQL-A nrPDB 209 1e-54 3GRP-A nrPDB 209 1e-54 6NRP-A nrPDB 209 1e-54 2Q2Q-A nrPDB 208 2e-54 2NM0-A nrPDB 207 7e-54 5VT6-A nrPDB 206 9e-54 3AUT-A nrPDB 206 1e-53 3W8F-A nrPDB 205 2e-53 5YSS-A nrPDB 205 3e-53 3T7C-A nrPDB 205 3e-53 1GEG-A nrPDB 204 4e-53 1GEE-A nrPDB 204 6e-53 3V2H-A nrPDB 202 1e-52 2GDZ-A nrPDB 202 1e-52 4CQM-B nrPDB 202 2e-52 3O4R-A nrPDB 202 2e-52 2AE2-A nrPDB 202 2e-52 3WTC-A nrPDB 201 4e-52 4IIV-A nrPDB 199 1e-51 5B1Y-A nrPDB 197 4e-51 1X1T-A nrPDB 197 4e-51 3UVE-A nrPDB 197 7e-51 2EW8-A nrPDB 195 2e-50 2CFC-A nrPDB 195 2e-50 3V2G-A nrPDB 195 3e-50 5OVL-A nrPDB 194 3e-50 3WYE-A nrPDB 194 3e-50 1YXM-A nrPDB 194 4e-50 2ZAT-A nrPDB 193 1e-49 4IS3-A nrPDB 192 1e-49 1NFF-A nrPDB 192 2e-49 5OVJ-A nrPDB 190 4e-49 5EJ2-A nrPDB 190 5e-49 4RZI-B nrPDB 190 6e-49 5U9P-A nrPDB 189 2e-48 3A28-C nrPDB 189 2e-48 1UZM-A nrPDB 188 3e-48 4Z9Y-A nrPDB 187 5e-48 1CYD-A nrPDB 186 1e-47 3U5T-A nrPDB 182 1e-46 4TRR-A nrPDB 182 2e-46 3D3W-A nrPDB 181 3e-46 4HP8-A nrPDB 181 3e-46 3RWB-A nrPDB 181 4e-46 3UF0-A nrPDB 180 5e-46 3OIC-A nrPDB 180 1e-45 3OML-A nrPDB 179 2e-45 6CI9-A nrPDB 179 2e-45 4FC7-A nrPDB 177 6e-45 5IZ4-A nrPDB 177 7e-45 4MOW-A nrPDB 175 2e-44 3RKU-A nrPDB 175 2e-44 1K2W-A nrPDB 175 2e-44 3V8B-A nrPDB 175 3e-44 2NWQ-A nrPDB 173 1e-43 4E6P-A nrPDB 173 1e-43 1O5I-A nrPDB 170 8e-43 2FWM-X nrPDB 167 6e-42 4RGB-A nrPDB 167 6e-42 2B4Q-A nrPDB 167 7e-42 2AG5-A nrPDB 166 1e-41 3ZV3-A nrPDB 164 7e-41 2O23-A nrPDB 163 8e-41 1E3W-A nrPDB 160 5e-40 1H5Q-A nrPDB 160 9e-40 2HSD-A nrPDB 159 2e-39 3UN1-A nrPDB 152 2e-37 5O3Z-A nrPDB 152 2e-37 1BDB-A nrPDB 148 2e-36 3PXX-A nrPDB 148 4e-36 3E9N-A nrPDB 147 6e-36 3DWF-A nrPDB 142 2e-34 5PGZ-A nrPDB 141 5e-34 2HRB-A nrPDB 138 3e-33 4DRY-A nrPDB 127 7e-30 1SNY-A nrPDB 127 7e-30 3U9L-A nrPDB 124 6e-29 Sequences not found previously or not previously below threshold: 4IIN-A nrPDB 189 1e-48 5OJG-A nrPDB 170 7e-43 5T5Q-A nrPDB 163 9e-41 4AVY-A nrPDB 158 3e-39 1DOH-A nrPDB 157 5e-39 1AHH-A nrPDB 153 9e-38 3R3S-A nrPDB 152 2e-37 1HXH-A nrPDB 147 8e-36 3GDF-A nrPDB 142 3e-34 5JS6-A nrPDB 140 7e-34 4CR6-A nrPDB 137 5e-33 5ILO-A nrPDB 137 8e-33 4EGF-A nrPDB 135 3e-32 2BGM-A nrPDB 133 9e-32 4HBG-A nrPDB 132 3e-31 5JY1-A nrPDB 130 7e-31 4DA9-A nrPDB 130 7e-31 3U4C-A nrPDB 128 4e-30 3BHI-A nrPDB 126 1e-29 1N5D-A nrPDB 126 1e-29 3KZV-A nrPDB 122 2e-28 2X9N-A nrPDB 115 2e-26 4GKB-A nrPDB 114 5e-26 1W73-A nrPDB 109 1e-24 3PPI-A nrPDB 109 2e-24 2BFA-A nrPDB 105 4e-23 2QHX-A nrPDB 104 4e-23 5L51-A nrPDB 104 5e-23 1B15-A nrPDB 104 6e-23 3O26-A nrPDB 102 2e-22 2P91-A nrPDB 101 3e-22 1P33-A nrPDB 99 3e-21 2YW9-A nrPDB 99 4e-21 1MG5-A nrPDB 95 5e-20 4HWK-A nrPDB 92 2e-19 4Z3K-A nrPDB 92 2e-19 1OAA-A nrPDB 92 3e-19 5KOI-A nrPDB 89 4e-18 5LCX-A nrPDB 87 1e-17 5TF4-A nrPDB 86 2e-17 5WQO-A nrPDB 84 1e-16 5TQV-A nrPDB 83 2e-16 3GRK-A nrPDB 82 5e-16 3OIG-A nrPDB 82 5e-16 2DKN-A nrPDB 81 8e-16 3UCF-A nrPDB 79 2e-15 4ALL-A nrPDB 77 7e-15 5I9N-A nrPDB 77 8e-15 5YCX-A nrPDB 76 3e-14 4M89-A nrPDB 76 3e-14 3SLK-A nrPDB 75 3e-14 3K2E-A nrPDB 75 3e-14 4ZJU-A nrPDB 74 7e-14 4NR0-A nrPDB 74 1e-13 2PD3-A nrPDB 72 3e-13 5CFZ-A nrPDB 70 9e-13 4JQC-A nrPDB 70 1e-12 4NK4-A nrPDB 69 3e-12 1FJH-A nrPDB 68 4e-12 4J3F-A nrPDB 68 6e-12 4Q9N-A nrPDB 65 4e-11 1ENP-A nrPDB 63 2e-10 2O2S-A nrPDB 63 2e-10 2NTV-A nrPDB 62 4e-10 4OYR-A nrPDB 61 6e-10 1I3M-A nrPDB 59 3e-09 4LIS-A nrPDB 56 2e-08 3F4B-A nrPDB 52 3e-07 3RFT-A nrPDB 52 3e-07 1UDA-A nrPDB 50 2e-06 2GN9-A nrPDB 50 2e-06 2PTG-A nrPDB 49 2e-06 1OOE-A nrPDB 48 4e-06 4R1T-A nrPDB 48 4e-06 3ORF-A nrPDB 47 9e-06 2O2Y-A nrPDB 46 2e-05 1GY8-A nrPDB 45 4e-05 1R66-A nrPDB 44 1e-04 1Z45-A nrPDB 43 2e-04 3ENK-A nrPDB 43 2e-04 1DIR-A nrPDB 42 4e-04 4G5H-A nrPDB 41 7e-04 2NNL-D nrPDB 40 0.001 5GUP-L nrPDB 40 0.001 1VL0-A nrPDB 40 0.002 4J2O-A nrPDB 39 0.002 6G2J-P nrPDB 39 0.003 2Q1W-A nrPDB 39 0.003 6BWL-A nrPDB 39 0.003 1ZZE-A nrPDB 39 0.003 1KEU-A nrPDB 38 0.005 6GCS-E nrPDB 38 0.006 3SXP-A nrPDB 38 0.007 4QUK-A nrPDB 38 0.008 5K1S-A nrPDB 37 0.011 4J6F-A nrPDB 37 0.015 1OC2-A nrPDB 36 0.021 2PZM-A nrPDB 36 0.021 2PK3-A nrPDB 36 0.024 4R1U-A nrPDB 35 0.034 1BXK-A nrPDB 35 0.038 2P4H-X nrPDB 33 0.13 1RPN-A nrPDB 33 0.14 2HUN-A nrPDB 33 0.14 6DEB-A nrPDB 33 0.16 5F5N-A nrPDB 33 0.17 2EXX-A nrPDB 33 0.19 2GGS-A nrPDB 33 0.20 5UZH-A nrPDB 32 0.28 1N7G-A nrPDB 32 0.32 5B6K-A nrPDB 32 0.34 3CT4-A nrPDB 32 0.35 4UUP-A nrPDB 32 0.43 3SC6-A nrPDB 32 0.48 6I3M-E nrPDB 32 0.51 6GPK-A nrPDB 32 0.54 1DB3-A nrPDB 31 0.76 3PVZ-A nrPDB 31 0.87 4E0B-A nrPDB 31 0.93 5ENV-A nrPDB 30 1.1 1O89-A nrPDB 30 1.2 1IQP-A nrPDB 30 1.4 4EJ6-A nrPDB 30 1.8 2X86-A nrPDB 30 2.0 1YXY-A nrPDB 30 2.2 4K28-A nrPDB 29 2.4 3N58-A nrPDB 29 2.4 5JJC-A nrPDB 29 2.7 4A10-A nrPDB 29 2.8 1IXR-A nrPDB 29 2.9 4EUF-A nrPDB 29 3.0 1QQV-A nrPDB 29 3.1 4AY7-A nrPDB 29 3.2 4A5O-A nrPDB 28 3.9 6NBY-D nrPDB 28 4.5 2Z95-A nrPDB 28 5.0 4H05-A nrPDB 28 5.1 1YFM-A nrPDB 28 5.4 4EJ0-A nrPDB 28 5.8 1Z1W-A nrPDB 28 5.8 4UUM-A nrPDB 28 6.2 5NUE-A nrPDB 28 6.8 4WOK-A nrPDB 28 8.1 1IIT-A nrPDB 28 8.1 5VEG-A nrPDB 28 8.2 5OHX-A nrPDB 28 8.2 5N2I-A nrPDB 28 8.4 5GXF-A nrPDB 27 9.0 1IE3-A nrPDB 27 9.0 1JAY-A nrPDB 27 9.2 >6CGE-A nrPDB Length = 328 Score = 454 bits (1167), Expect = e-128, Method: Composition-based stats. Identities = 328/328 (100%), Positives = 328/328 (100%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL Sbjct: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 Query: 61 ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV Sbjct: 61 ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 Query: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH Sbjct: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180 Query: 181 LSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV 240 LSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV Sbjct: 181 LSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV 240 Query: 241 FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFGDVPAKAEAGAEAGG 300 FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFGDVPAKAEAGAEAGG Sbjct: 241 FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFGDVPAKAEAGAEAGG 300 Query: 301 GAGPGAEDEAGRGAVGDPELGDPPAAPQ 328 GAGPGAEDEAGRGAVGDPELGDPPAAPQ Sbjct: 301 GAGPGAEDEAGRGAVGDPELGDPPAAPQ 328 >1A27-A nrPDB Length = 289 Score = 385 bits (990), Expect = e-107, Method: Composition-based stats. Identities = 289/289 (100%), Positives = 289/289 (100%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE Sbjct: 1 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 60 Query: 62 TLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 TLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR Sbjct: 61 TLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 120 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL Sbjct: 121 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 180 Query: 182 SLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVF 241 SLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVF Sbjct: 181 SLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVF 240 Query: 242 LTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFGDVPA 290 LTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFGDVPA Sbjct: 241 LTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFGDVPA 289 >4JRO-A nrPDB Length = 271 Score = 247 bits (632), Expect = 4e-66, Method: Composition-based stats. Identities = 65/267 (24%), Positives = 121/267 (45%), Gaps = 26/267 (9%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + V ++TG S GIG +A+ LA + + F Y + E A+ +A + Sbjct: 27 LQGKVAVVTGGSRGIGRDIAINLAKEGANIFFNY-----NGSPEAAEETAKLVAEHGVEV 81 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 E ++ +V ++ V A ++ E GRVD+LV NAG+ L + ED V+++N+ G Sbjct: 82 EAMKANVAIAEDVDAFFKQAIERFGRVDILVNNAGITRDNLLMRMKEDEWDDVININLKG 141 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 T +A M ++ +G+++ SV GL+G Y ASK + GL ++ A L P G Sbjct: 142 TFLCTKAVSRTMMKQRAGKIINMASVVGLIGNAGQANYVASKAGVIGLTKTTARELAPRG 201 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 ++++ + G + T +K+ +E + Q+ A E++A Sbjct: 202 INVNAVAPGFITTDMTDKLDEKTKEAM-----------------LAQIPLGAYGTTEDIA 244 Query: 239 EV--FLTALRAPKPTLRYFTTERFLPL 263 FL + + T + + + + + Sbjct: 245 NAVLFLASDASKYITGQTLSVDGGMVM 271 >2C07-A nrPDB Length = 285 Score = 245 bits (626), Expect = 2e-65, Method: Composition-based stats. Identities = 54/264 (20%), Positives = 89/264 (33%), Gaps = 27/264 (10%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 V L+TG GIG +A LA S + T + + Sbjct: 43 ENKVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKS------CDSVVDEIKSFGYESS 96 Query: 62 TLQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGT 119 DV + ++ ++ VD+LV NAG+ + D VL N+ Sbjct: 97 GYAGDVSKKEEISEVINKILTEHKNVDILVNNAGITRDNLFLRMKNDEWEDVLRTNLNSL 156 Query: 120 VRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGV 179 + Q M GR++ S+ GL G Y +SK + G +SLA L + Sbjct: 157 FYITQPISKRMINNRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKELASRNI 216 Query: 180 HLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE 239 ++ I G + + +K+ + PEEVA Sbjct: 217 TVNAIAPGFISSDMTDKISEQ-----------------IKKNIISNIPAGRMGTPEEVAN 259 Query: 240 V--FLTALRAPKPTLRYFTTERFL 261 + FL++ ++ R F + L Sbjct: 260 LACFLSSDKSGYINGRVFVIDGGL 283 >2PNF-A nrPDB Length = 248 Score = 244 bits (623), Expect = 4e-65, Method: Composition-based stats. Identities = 62/265 (23%), Positives = 101/265 (38%), Gaps = 26/265 (9%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + V L+TG + GIG +A +LAS S + K Sbjct: 5 LQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIA-----NKYGVKA 59 Query: 61 ETLQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 +++++ +S+ A E + +D+LV NAG+ + VL VN+ G Sbjct: 60 HGVEMNLLSEESINKAFEEIYNLVDGIDILVNNAGITRDKLFLRMSLLDWEEVLKVNLTG 119 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 T + Q L M ++ GR++ SV G G Y +K L G +SLA L P Sbjct: 120 TFLVTQNSLRKMIKQRWGRIVNISSVVGFTGNVGQVNYSTTKAGLIGFTKSLAKELAPRN 179 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 V ++ + G + T + EE+ + + +Q+ +PEEVA Sbjct: 180 VLVNAVAPGFIETDMTAVL---SEEIKQK--------------YKEQIPLGRFGSPEEVA 222 Query: 239 EV--FLTALRAPKPTLRYFTTERFL 261 V FL + A T + Sbjct: 223 NVVLFLCSELASYITGEVIHVNGGM 247 >2UVD-A nrPDB Length = 246 Score = 243 bits (620), Expect = 8e-65, Method: Composition-based stats. Identities = 56/267 (20%), Positives = 107/267 (40%), Gaps = 26/267 (9%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + V L+TG S GIG +A+ LA + YA + + E + Sbjct: 2 LKGKVALVTGASRGIGRAIAIDLAKQGANVVVNYA-----GNEQKANEVVDEIKKLGSDA 56 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 ++ DV +++ V ++ + G+VD+LV NAG+ L + E+ +V++ N+ G Sbjct: 57 IAVRADVANAEDVTNMVKQTVDVFGQVDILVNNAGVTKDNLLMRMKEEEWDTVINTNLKG 116 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 +A M R+ GR++ SV G+ G P Y A+K + GL ++ A L Sbjct: 117 VFLCTKAVSRFMMRQRHGRIVNIASVVGVTGNPGQANYVAAKAGVIGLTKTSAKELASRN 176 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 + ++ I G + T +VLD + + +++A Sbjct: 177 ITVNAIAPGFIATDMT--------DVLDENIKAEMLKL---------IPAAQFGEAQDIA 219 Query: 239 EV--FLTALRAPKPTLRYFTTERFLPL 263 F + ++ T + + + + Sbjct: 220 NAVTFFASDQSKYITGQTLNVDGGMVM 246 >3OSU-A nrPDB Length = 246 Score = 241 bits (616), Expect = 3e-64, Method: Composition-based stats. Identities = 60/264 (22%), Positives = 104/264 (39%), Gaps = 26/264 (9%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETL 63 L+TG S GIG +A++LA + YA ++ + + + Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYA-----GSKEKAEAVVEEIKAKGVDSFAI 59 Query: 64 QLDVRDSKSVAAARERVT--EGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 Q +V D+ V A + V G +DVLV NAG+ L + E V+D N+ G Sbjct: 60 QANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFN 119 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 +Q P M R+ SG ++ SV G +G P Y A+K + GL +S A L G+ + Sbjct: 120 CIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITV 179 Query: 182 SLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE-- 239 + + G + + + + +E + Q+ ++A Sbjct: 180 NAVAPGFIVSDMTDALSDELKEQM-----------------LTQIPLARFGQDTDIANTV 222 Query: 240 VFLTALRAPKPTLRYFTTERFLPL 263 FL + +A T + + + Sbjct: 223 AFLASDKAKYITGQTIHVNGGMYM 246 >2HQ1-A nrPDB Length = 247 Score = 233 bits (595), Expect = 6e-62, Method: Composition-based stats. Identities = 55/267 (20%), Positives = 106/267 (39%), Gaps = 26/267 (9%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + ++TG S G+G +A +L + + L L A ++ Sbjct: 3 LKGKTAIVTGSSRGLGKAIAWKLGNMGANIV-----LNGSPASTSLDATAEEFKAAGINV 57 Query: 61 ETLQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 + DV++ + V + GR+D+LV NAG+ + + E VL+ N+ Sbjct: 58 VVAKGDVKNPEDVENMVKTAMDAFGRIDILVNNAGITRDTLMLKMSEKDWDDVLNTNLKS 117 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 +A M ++ SG+++ S+ G++G Y ASK L G +S+A G Sbjct: 118 AYLCTKAVSKIMLKQKSGKIINITSIAGIIGNAGQANYAASKAGLIGFTKSIAKEFAAKG 177 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 ++ + + G + T + + P++V + + + + PEEVA Sbjct: 178 IYCNAVAPGIIKTDMTDVL---PDKVKE--------------MYLNNIPLKRFGTPEEVA 220 Query: 239 EV--FLTALRAPKPTLRYFTTERFLPL 263 V FL + + T + + L + Sbjct: 221 NVVGFLASDDSNYITGQVINIDGGLVM 247 >3WOH-A nrPDB Length = 251 Score = 232 bits (593), Expect = 1e-61, Method: Composition-based stats. Identities = 61/267 (22%), Positives = 109/267 (40%), Gaps = 28/267 (10%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 ++ V L+TG S G+G +A+RLA D + VY + E + G+ Sbjct: 9 LSGKVALVTGGSRGLGRAMALRLARDGAAVAIVYVS-----DDSSAKETQGEIERLGGTA 63 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 + + DV D++ V + VT G VD+LV NAG+ G ++ ++ +V++ N+ G Sbjct: 64 RSYRCDVSDAEQVTRCVKAVTADLGPVDILVNNAGIIRDGLAASIKDEDYDAVMNTNLKG 123 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 ++A R+ SG ++ SV G+ G Y ++K L GL +S+A L Sbjct: 124 AFLFIKACYFGFIRKRSGSIINISSVSGVFGSAGQANYASAKAGLIGLTKSIAKELAERN 183 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 V + + G + T + ++ + V P+EVA Sbjct: 184 VRCNAVAPGLIATDMTQDLVDDSKR-------------------LDPVPMRRFGRPDEVA 224 Query: 239 E--VFLTALRAPKPTLRYFTTERFLPL 263 FL + T + + + + Sbjct: 225 GLVAFLAGDESSYITGQVVCVDGGMAM 251 >3RSH-A nrPDB Length = 251 Score = 227 bits (580), Expect = 4e-60, Method: Composition-based stats. Identities = 60/268 (22%), Positives = 109/268 (40%), Gaps = 30/268 (11%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + V L+TG S GIG +A LA ++ + + + Sbjct: 10 LEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISD---------YLGDNG 60 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 + + L+V + +S+ A + +T+ G VD+LV NAG+ L + E+ + +++ N+ Sbjct: 61 KGMALNVTNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTS 120 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 R+ +A L M ++ GR++ GSV G MG Y A+K + G +S+A + G Sbjct: 121 IFRLSKAVLRGMMKKRQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVASRG 180 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 V ++ + G + T + + Q A QV +P E+A Sbjct: 181 VTVNTVAPGFIETDMTKALNDE-----------------QRTATLAQVPAGRLGDPREIA 223 Query: 239 E--VFLTALRAPKPTLRYFTTERFLPLL 264 FL + A T + ++ Sbjct: 224 SAVAFLASPEAAYITGETLHVNGGMYMI 251 >2PH3-A nrPDB Length = 245 Score = 226 bits (577), Expect = 9e-60, Method: Composition-based stats. Identities = 67/260 (25%), Positives = 110/260 (42%), Gaps = 25/260 (9%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 LITG S GIG +A+RLA D Y + A A + L Sbjct: 4 ALITGASRGIGRAIALRLAEDGFALAIHYG----QNREKAEEVAEEARRRGSPLVAVLGA 59 Query: 66 DVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRML 123 ++ ++++ A + E G +D LV NAG+ L + ++ +VL+ N+ R Sbjct: 60 NLLEAEAATALVHQAAEVLGGLDTLVNNAGITRDTLLVRMKDEDWEAVLEANLSAVFRTT 119 Query: 124 QAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSL 183 + + M + GR++ SV G++G P Y ASK L G ++A G+ ++ Sbjct: 120 REAVKLMMKARFGRIVNITSVVGILGNPGQANYVASKAGLIGFTRAVAKEYAQRGITVNA 179 Query: 184 IECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE--VF 241 + G + T E++ P+EV + A+ KQ+ PEEVAE F Sbjct: 180 VAPGFIETEMTERL---PQEVKE--------------AYLKQIPAGRFGRPEEVAEAVAF 222 Query: 242 LTALRAPKPTLRYFTTERFL 261 L + +A T + + L Sbjct: 223 LVSEKAGYITGQTLCVDGGL 242 >4RZH-A nrPDB Length = 247 Score = 225 bits (573), Expect = 3e-59, Method: Composition-based stats. Identities = 61/269 (22%), Positives = 105/269 (39%), Gaps = 30/269 (11%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + V L+TG S GIG A+ LA+ + YA ++ + G Sbjct: 4 LTAQVALVTGASRGIGKATALALAATGMKVVVNYA-----QSSTAADAVVAEIIANGGEA 58 Query: 61 ETLQLDVRDSKSVAAARERVTEG--RVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 +Q +V ++ V + + R+DVLV NAG+ L + + +V+D+N+ G Sbjct: 59 IAVQANVANADEVDQLIKTTLDKFSRIDVLVNNAGITRDTLLLRMKLEDWQAVIDLNLTG 118 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 +A M ++ SGR++ SV G+MG P Y A+K + G +++A L G Sbjct: 119 VFLCTKAVSKLMLKQKSGRIINITSVAGMMGNPGQANYSAAKAGVIGFTKTVAKELASRG 178 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 V ++ + G + T E + P + + PEEVA Sbjct: 179 VTVNAVAPGFIATDMTENLNAEP--------------------ILQFIPLARYGQPEEVA 218 Query: 239 EVFLTALRAPK---PTLRYFTTERFLPLL 264 P T + F + + + Sbjct: 219 GTIRFLATDPAAAYITGQTFNVDGGMVMF 247 >3LYL-A nrPDB Length = 247 Score = 224 bits (572), Expect = 3e-59, Method: Composition-based stats. Identities = 56/267 (20%), Positives = 104/267 (38%), Gaps = 27/267 (10%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + V L+TG S GIG +A LAS + + + + Sbjct: 3 LNEKVALVTGASRGIGFEVAHALASKGATVVGTATSQASAEKFENSMKEK------GFKA 56 Query: 61 ETLQLDVRDSKSVAAARERVTEG--RVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 L L++ D +S+ + +D+LV NAG+ + + ED SV++ N+ Sbjct: 57 RGLVLNISDIESIQNFFAEIKAENLAIDILVNNAGITRDNLMMRMSEDEWQSVINTNLSS 116 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 RM + + M ++ GR++ GSV G G P YCA+K + G +SLA + Sbjct: 117 IFRMSKECVRGMMKKRWGRIISIGSVVGSAGNPGQTNYCAAKAGVIGFSKSLAYEVASRN 176 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 + ++++ G + T +K+ Q + ++ P+++A Sbjct: 177 ITVNVVAPGFIATDMTDKLTDE-----------------QKSFIATKIPSGQIGEPKDIA 219 Query: 239 E--VFLTALRAPKPTLRYFTTERFLPL 263 FL + A T + + + Sbjct: 220 AAVAFLASEEAKYITGQTLHVNGGMYM 246 >3FTP-A nrPDB Length = 270 Score = 221 bits (563), Expect = 4e-58, Method: Composition-based stats. Identities = 63/267 (23%), Positives = 109/267 (40%), Gaps = 27/267 (10%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + + V ++TG S GIG +A+ LA + T + G ++ A Sbjct: 26 LDKQVAIVTGASRGIGRAIALELARRGAMVIGTATTEAGAEGIGAAFKQA------GLEG 79 Query: 61 ETLQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 L+V D+ +V A E G ++VLV NAG+ + +D +V+D N+ Sbjct: 80 RGAVLNVNDATAVDALVESTLKEFGALNVLVNNAGITQDQLAMRMKDDEWDAVIDTNLKA 139 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 R+ +A L M + GR++ SV G G P Y A+K + G+ +LA + G Sbjct: 140 VFRLSRAVLRPMMKARGGRIVNITSVVGSAGNPGQVNYAAAKAGVAGMTRALAREIGSRG 199 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 + ++ + G + T + G P+E Q A Q+ +PE++A Sbjct: 200 ITVNCVAPGFIDTDMTK---GLPQE--------------QQTALKTQIPLGRLGSPEDIA 242 Query: 239 E--VFLTALRAPKPTLRYFTTERFLPL 263 FL + +A T + + Sbjct: 243 HAVAFLASPQAGYITGTTLHVNGGMFM 269 >4DMM-A nrPDB Length = 269 Score = 221 bits (562), Expect = 5e-58, Method: Composition-based stats. Identities = 67/265 (25%), Positives = 114/265 (43%), Gaps = 24/265 (9%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + + L+TG S GIG +A+ LA+ ++ YA+ + G E A+A G Sbjct: 26 LTDRIALVTGASRGIGRAIALELAAAGAKVAVNYAS-----SAGAADEVVAAIAAAGGEA 80 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 ++ DV V A V E GR+DVLV NAG+ L + D SVLD+N+ G Sbjct: 81 FAVKADVSQESEVEALFAAVIERWGRLDVLVNNAGITRDTLLLRMKRDDWQSVLDLNLGG 140 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 +A M ++ SGR++ SV G MG P Y A+K + GL +++A L G Sbjct: 141 VFLCSRAAAKIMLKQRSGRIINIASVVGEMGNPGQANYSAAKAGVIGLTKTVAKELASRG 200 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 + ++ + G + T ++ E++L+ + + + + + + A Sbjct: 201 ITVNAVAPGFIATDMTSELAA--EKLLEVIPLGRYGEAAEVAGVVRFLAADPA------- 251 Query: 239 EVFLTALRAPKPTLRYFTTERFLPL 263 A T + + L + Sbjct: 252 --------AAYITGQVINIDGGLVM 268 >2CDH-G nrPDB Length = 244 Score = 221 bits (562), Expect = 5e-58, Method: Composition-based stats. Identities = 57/264 (21%), Positives = 104/264 (39%), Gaps = 27/264 (10%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 VV++TG S GIG +A+ L + YA ++ E ++ + G T Sbjct: 3 VVVVTGASRGIGKAIALSLGKAGCKVLVNYA-----RSAKAAEEVSKQIEAYGGQAITFG 57 Query: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 DV V A + + G +DV+V NAG+ L + + V+D+N+ G Sbjct: 58 GDVSKEADVEAMMKTAIDAWGTIDVVVNNAGITRDTLLIRMKKSQWDEVIDLNLTGVFLC 117 Query: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLS 182 QA M ++ GR++ SV GL+G Y A+K + G ++ A ++++ Sbjct: 118 TQAATKIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNINVN 177 Query: 183 LIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVFL 242 ++ G + + K+ E+ + + PE VA + Sbjct: 178 VVCPGFIASDMTAKLGEDMEKKI-----------------LGTIPLGRTGQPENVAGLVE 220 Query: 243 TALRAPK---PTLRYFTTERFLPL 263 +P T + FT + + + Sbjct: 221 FLALSPAASYITGQAFTIDGGIAI 244 >4K6F-A nrPDB Length = 255 Score = 220 bits (561), Expect = 6e-58, Method: Composition-based stats. Identities = 61/264 (23%), Positives = 100/264 (37%), Gaps = 25/264 (9%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 M + + ++TG G+G +++RL +V T T W + Sbjct: 9 MTKRIAVVTGGMGGLGEAVSIRLNDAG---HRVVVTYSPNNTGADRW--LTEMHAAGREF 63 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 +DV D S E++ G VD+LV NAG+ L L + +V+ N+ Sbjct: 64 HAYPVDVADHDSCQQCIEKIVRDVGPVDILVNNAGITRDMTLRKLDKVNWDAVIRTNLDS 123 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 M + M RG GR++ SV G G Y A+K + G +SLA+ + G Sbjct: 124 VFNMTKPVCDGMVERGWGRIVNISSVNGSKGSVGQTNYAAAKAGMHGFTKSLALEIARKG 183 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 V ++ + G + T + + P+++LD Q+ PEEVA Sbjct: 184 VTVNTVSPGYLATKMVTAI---PQDILDTK-------------ILPQIPAGRLGKPEEVA 227 Query: 239 E--VFLTALRAPKPTLRYFTTERF 260 +L + A T Sbjct: 228 ALVAYLCSEEAGFVTGSNIAINGG 251 >5CDY-A nrPDB Length = 244 Score = 220 bits (560), Expect = 8e-58, Method: Composition-based stats. Identities = 57/267 (21%), Positives = 101/267 (37%), Gaps = 30/267 (11%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 + L+TG S GIG +A L + + + + A + + Sbjct: 4 EGKIALVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAIS---------AYLGENGK 54 Query: 62 TLQLDVRDSKSVAAARE--RVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGT 119 L L+V D S+ R G VD+LV NAG+ L + +D ++D N+ Sbjct: 55 GLMLNVVDPTSIDTVLATIRAEFGEVDILVNNAGITRDNLLMRMKDDEWQDIIDTNLTSV 114 Query: 120 VRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGV 179 R+ +A + M ++ GR++ GSV G MG Y A+K + G +SLA + G+ Sbjct: 115 FRLSKAVMRAMMKKRFGRIITIGSVVGTMGNAGQVNYAAAKAGVIGFSKSLAREVASRGI 174 Query: 180 HLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE 239 ++++ G + T + Q QV + +E+A Sbjct: 175 TVNVVAPGFIETDMTRTLTDD-----------------QRAGILAQVPANRLGDAKEIAS 217 Query: 240 --VFLTALRAPKPTLRYFTTERFLPLL 264 FL + A + + ++ Sbjct: 218 AVAFLASDEASYISGETLHVNGGMYMI 244 >1Q7C-A nrPDB Length = 244 Score = 219 bits (558), Expect = 1e-57, Method: Composition-based stats. Identities = 57/267 (21%), Positives = 103/267 (38%), Gaps = 30/267 (11%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 + L+TG S GIG +A LA+ ++ + + + + Sbjct: 4 EGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISD---------YLGANGK 54 Query: 62 TLQLDVRDSKSVAAARE--RVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGT 119 L L+V D S+ + E R G VD+LV NAG+ L + ++ +++ N+ Sbjct: 55 GLMLNVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSV 114 Query: 120 VRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGV 179 R+ +A + M ++ GR++ GSV G MG + A+K L G +SLA + G+ Sbjct: 115 FRLSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANFAAAKAGLIGFSKSLAREVASRGI 174 Query: 180 HLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE 239 ++++ G + T + Q QV +E+A Sbjct: 175 TVNVVAPGFIETDMTRALSDD-----------------QRAGILAQVPAGRLGGAQEIAN 217 Query: 240 --VFLTALRAPKPTLRYFTTERFLPLL 264 FL + A T + ++ Sbjct: 218 AVAFLASDEAAYITGETLHVNGGMYMV 244 >4KMS-A nrPDB Length = 249 Score = 219 bits (557), Expect = 2e-57, Method: Composition-based stats. Identities = 53/261 (20%), Positives = 100/261 (38%), Gaps = 32/261 (12%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 + ++TG + GIG A+ L + + + ++AA+ + G ++T Sbjct: 12 IAIVTGGTRGIGKATALELKNKGLTVVANFFS---------NYDAAKEMEEKYG-IKTKC 61 Query: 65 LDVRDSKSVAAARERVTE---GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 +V D + A + + E V +LV NAG+ L + V++VN+ Sbjct: 62 WNVADFEECRQAVKEIEEEFKKPVSILVNNAGITKDKMLHRMSHQDWNDVINVNLNSCFN 121 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 M + + M+ + GR++ S+ G Y A+K + G ++LA + + Sbjct: 122 MSSSVMEQMRNQDYGRIVNISSINAQAGQVGQTNYSAAKAGIIGFTKALARETASKNITV 181 Query: 182 SLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE-- 239 + I G + T + V PE+VL + + ++ PEE+A Sbjct: 182 NCIAPGYIATEMVGAV---PEDVLAK--------------IINSIPKKRLGQPEEIARAV 224 Query: 240 VFLTALRAPKPTLRYFTTERF 260 FL A T + Sbjct: 225 AFLVDENAGFITGETISINGG 245 >3F9I-A nrPDB Length = 249 Score = 218 bits (556), Expect = 2e-57, Method: Composition-based stats. Identities = 54/266 (20%), Positives = 106/266 (39%), Gaps = 30/266 (11%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + LITG SSGIG +A L S+ + LK+ G + + Sbjct: 12 LTGKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYTIE------ 65 Query: 61 ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 ++ + + + + + +D+LVCNAG+ + + V+D+N+ Sbjct: 66 ---VCNLANKEECSNLISKTSN--LDILVCNAGITSDTLAIRMKDQDFDKVIDINLKANF 120 Query: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180 + + + M ++ GR++ S+ G+ G P YCASK L G+ +SL+ + G+ Sbjct: 121 ILNREAIKKMIQKRYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYEVATRGIT 180 Query: 181 LSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE- 239 ++ + G + + +K+ Q A +++ PE+VA Sbjct: 181 VNAVAPGFIKSDMTDKLNEK-----------------QREAIVQKIPLGTYGIPEDVAYA 223 Query: 240 -VFLTALRAPKPTLRYFTTERFLPLL 264 FL + A T + + ++ Sbjct: 224 VAFLASNNASYITGQTLHVNGGMLMV 249 >5ITV-A nrPDB Length = 255 Score = 218 bits (556), Expect = 2e-57, Method: Composition-based stats. Identities = 67/270 (24%), Positives = 104/270 (38%), Gaps = 33/270 (12%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + VLITG +SGIG + + R L Sbjct: 5 LTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRKE--------NNDRL 56 Query: 61 ETLQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 +Q D+ D + A E T G +DVL+ NAG+ ++ P+ + VL VN+ G Sbjct: 57 HFVQTDITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTG 116 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 M + L M G G ++ T SVGGL+ P Y ASK + L +S+AV Sbjct: 117 MFLMSKHALKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQ 176 Query: 179 VHLSLIECGPVHTAFMEKVL-----GSPEEV-LDRTDIHTFHRFYQYLAHSKQVFREAAQ 232 + ++ + G + T EK G+ EE+ ++ ++ R Sbjct: 177 IRVNCVCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRLG--------------- 221 Query: 233 NPEEVAEV--FLTALRAPKPTLRYFTTERF 260 PEE+A V FL + + T T + Sbjct: 222 KPEEIANVMLFLASDLSSYMTGSAITADGG 251 >4NBV-A nrPDB Length = 246 Score = 217 bits (552), Expect = 6e-57, Method: Composition-based stats. Identities = 74/267 (27%), Positives = 109/267 (40%), Gaps = 27/267 (10%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + V +ITG ++GIG A R A D + + R+ EAA LA ++ Sbjct: 3 LQGRVAIITGAAAGIGFATAQRFAEDGAIVVLCDV------QEARVREAAARLAATGATV 56 Query: 61 ETLQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 ++DV V A V RVD+LV NAG+ L + E +V+DVN+ G Sbjct: 57 SAYRVDVTRRDEVDAMVAAVLAAHQRVDILVNNAGITKDARLAKMTEAQFDAVIDVNLKG 116 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 QA M +G G +L SV GL G Y ASKF + G ++ A L P G Sbjct: 117 VFNCAQAVAGLMTEQGKGVILNASSVVGLYGNFGQTNYAASKFGVIGFTKTWARELGPKG 176 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 V ++ + G V+T ++ V P++VLD + + P E+A Sbjct: 177 VRVNAVCPGFVNTEILQTV---PDKVLD--------------GMTSSCWLRRLAEPAEIA 219 Query: 239 E--VFLTALRAPKPTLRYFTTERFLPL 263 FL + A + L Sbjct: 220 SIYAFLASDDASYVNGVAIEASGGMSL 246 >3VZS-A nrPDB Length = 257 Score = 216 bits (549), Expect = 2e-56, Method: Composition-based stats. Identities = 56/264 (21%), Positives = 98/264 (37%), Gaps = 26/264 (9%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 + + +TG GIG + RLA D + R + Sbjct: 13 TQRIAYVTGGMGGIGTAICQRLAKDGFRVVAGCG-----PNSPRREKWLEQQKALGFDFI 67 Query: 62 TLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGT 119 + +V D S A ++V G VDVL+ NAG+ + +V+D N+ Sbjct: 68 ASEGNVADWDSTKTAFDKVKSEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSL 127 Query: 120 VRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGV 179 + + + M RG GR++ SV G G Y +K L G +LA + GV Sbjct: 128 FNVTKQVIDGMADRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGV 187 Query: 180 HLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE 239 ++ + G + T ++ + ++VLD+ + + PEE+A Sbjct: 188 TVNTVSPGYIATDMVKAIR---QDVLDK--------------IVATIPVKRLGLPEEIAS 230 Query: 240 --VFLTALRAPKPTLRYFTTERFL 261 +L++ + T F+ L Sbjct: 231 ICAWLSSEESGFSTGADFSLNGGL 254 >4NBT-A nrPDB Length = 240 Score = 215 bits (547), Expect = 2e-56, Method: Composition-based stats. Identities = 61/269 (22%), Positives = 107/269 (39%), Gaps = 38/269 (14%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + V +ITG + G+G +A+ A + ++ L ++ Sbjct: 4 LEGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDL---------------GDLTYSHPNV 48 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 E + L+V D V + V + G++D+LV NAG+ + E +V+DVN+ G Sbjct: 49 EGMYLNVTDVTGVEKFYQSVIDKYGKIDILVNNAGITKDAMTRKMTEAQWDAVIDVNLKG 108 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLL--P 176 + + P M+ G G ++ SV G+ G Y A+K + GL + A Sbjct: 109 VFNLTRLVGPQMQTNGYGSIINISSVVGVFGNIGQANYAATKAGVIGLTMTWAKEFALKG 168 Query: 177 FGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEE 236 V ++ I G + T ++ V P+++LD+ T PEE Sbjct: 169 ANVRVNAIAPGYIMTDILKTV---PQDLLDKFAALTM--------------LNRLGQPEE 211 Query: 237 VAEV--FLTALRAPKPTLRYFTTERFLPL 263 +A+V FL + A T + + L Sbjct: 212 IAKVALFLASDDASYVTGQTINVNGGMRL 240 >3EZL-A nrPDB Length = 256 Score = 214 bits (545), Expect = 4e-56, Method: Composition-based stats. Identities = 55/265 (20%), Positives = 99/265 (37%), Gaps = 26/265 (9%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 M++ + +TG GIG + RL D F+V A + W Sbjct: 11 MSQRIAYVTGGMGGIGTSICQRLHKDG---FRVVAGCGPNSPRRVKW--LEDQKALGFDF 65 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 + +V D S A ++V G +DVLV NAG+ + + +V+D N+ Sbjct: 66 YASEGNVGDWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTREDWQAVIDTNLTS 125 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 + + + M RG GR++ SV G G Y +K + G SLA + G Sbjct: 126 LFNVTKQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVATKG 185 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 V ++ + G + T ++ + +VL++ + +P+E+ Sbjct: 186 VTVNTVSPGYIGTDMVKAIR---PDVLEK--------------IVATIPVRRLGSPDEIG 228 Query: 239 EVFLT--ALRAPKPTLRYFTTERFL 261 + + + T F+ L Sbjct: 229 SIVAWLASEESGFSTGADFSLNGGL 253 >3OEC-A nrPDB Length = 317 Score = 212 bits (539), Expect = 2e-55, Method: Composition-based stats. Identities = 65/254 (25%), Positives = 102/254 (40%), Gaps = 15/254 (5%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRD------LKTQGRLWEAARALA 54 + V ITG + G G AVRLA D + + + + L E R + Sbjct: 44 LQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKETVRLVE 103 Query: 55 CPPGSLETLQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVL 112 + Q DVRD S+ A + G +D+LV N G+ G + +L + + +L Sbjct: 104 EQGRRIIARQADVRDLASLQAVVDEALAEFGHIDILVSNVGISNQGEVVSLTDQQWSDIL 163 Query: 113 DVNVVGTVRMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLA 171 N++G +A LP M RG G V+ S GL G P Y ASK ++GL SLA Sbjct: 164 QTNLIGAWHACRAVLPSMIERGQGGSVIFVSSTVGLRGAPGQSHYAASKHGVQGLMLSLA 223 Query: 172 VLLLPFGVHLSLIECGPVHTAF--MEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFRE 229 + + ++ + G V+T EK+L ++ + L + Sbjct: 224 NEVGRHNIRVNSVNPGAVNTEMALNEKLL----KMFLPHLENPTREDAAELFSQLTLLPI 279 Query: 230 AAQNPEEVAEVFLT 243 PE+V+ Sbjct: 280 PWVEPEDVSNAVAW 293 >3EMK-A nrPDB Length = 246 Score = 212 bits (539), Expect = 2e-55, Method: Composition-based stats. Identities = 59/269 (21%), Positives = 107/269 (39%), Gaps = 32/269 (11%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + L+TG + G+G +A L + + G E + LA G Sbjct: 5 LTGRKALVTGATGGLGEAIARALHAQGAIV----------GLHGTREEKLKELAAELGER 54 Query: 61 ETL-QLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVV 117 + ++ D ++V A ++ E G VD+LV NAG+ G + ++ +VL VN+ Sbjct: 55 IFVFPANLSDREAVKALGQKAEEEMGGVDILVNNAGITRDGLFVRMSDEDWDAVLTVNLT 114 Query: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 + + M RR +GR++ S+ G+ G P YCASK L G +SLA + Sbjct: 115 SVFNLTRELTHPMMRRRNGRIINITSIVGVTGNPGQANYCASKAGLIGFSKSLAQEIASR 174 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV 237 V ++ I G + +A K+ ++ A + + ++ Sbjct: 175 NVTVNCIAPGFIESAMTGKLNEKQKD-----------------AIMGNIPMKRMGVGADI 217 Query: 238 AE--VFLTALRAPKPTLRYFTTERFLPLL 264 A V+L + A T + + ++ Sbjct: 218 AAAVVYLASDEAAYVTGQTLHVNGGMAMI 246 >4M8S-A nrPDB Length = 248 Score = 211 bits (538), Expect = 3e-55, Method: Composition-based stats. Identities = 58/267 (21%), Positives = 110/267 (41%), Gaps = 29/267 (10%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 ++ + L+TG S GIG +A LA+ ++ + + + LA G Sbjct: 6 LSGKIALVTGASRGIGAAIADTLAAAGAKVIGTATS------ESGAAAISERLAQWGG-- 57 Query: 61 ETLQLDVRDSKSVAAARE--RVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 E L+ + ++V T G++D+LV NAG+ L + E+ ++ VN+ Sbjct: 58 EGRVLNSAEPETVENLIADIEKTFGKLDILVNNAGITRDNLLMRMKEEEWDDIMQVNLKS 117 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 R +A L M ++ +GR++ SV G+MG Y A+K L G +S+A + G Sbjct: 118 VFRASKAVLRGMMKQRAGRIINITSVVGVMGNAGQTNYAAAKAGLIGFSKSMAREVGSRG 177 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 + ++ + G + T + PEE + Q + +++A Sbjct: 178 ITVNCVAPGFIDTDMTRAL---PEE--------------TRQTFTAQTALGRFGDAQDIA 220 Query: 239 EV--FLTALRAPKPTLRYFTTERFLPL 263 + FL + +A T + + + Sbjct: 221 DAVLFLASDQAKYITGQTLHVNGGMLM 247 >4BO1-A nrPDB Length = 269 Score = 211 bits (537), Expect = 4e-55, Method: Composition-based stats. Identities = 67/267 (25%), Positives = 108/267 (40%), Gaps = 27/267 (10%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + V L+TG S GIG +A+ L + V T ++ E +A Sbjct: 25 LQGKVALVTGASRGIGQAIALELGRLGA---VVIGTATSASGAEKIAETLKANGVEGA-- 79 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 L LDV +SVAA E + + G+ ++V NAG+ L + +D V++ N+ Sbjct: 80 -GLVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEWFDVVNTNLNS 138 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 R+ +A L M + GR++ GSV G MG Y A+K LEG +LA + Sbjct: 139 LYRLSKAVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSRA 198 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 + ++ + G + T ++ PE Q A Q+ EE+A Sbjct: 199 ITVNAVAPGFIDTDMTREL---PEA--------------QREALLGQIPLGRLGQAEEIA 241 Query: 239 EV--FLTALRAPKPTLRYFTTERFLPL 263 +V FL + A T + + Sbjct: 242 KVVGFLASDGAAYVTGATVPVNGGMYM 268 >4DBZ-A nrPDB Length = 281 Score = 210 bits (535), Expect = 6e-55, Method: Composition-based stats. Identities = 72/263 (27%), Positives = 108/263 (41%), Gaps = 18/263 (6%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 V L+TG +SGIGL +A RL + + F L+T + L + Sbjct: 28 VALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRT------TLKELREAGVEADGRT 81 Query: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 DVR + A V E G VDVLV NAG G L ++ V++ N+ G R+ Sbjct: 82 CDVRSVPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELADELWLDVVETNLTGVFRV 141 Query: 123 LQAFLPD--MKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180 + L M RG+GR++ S GG GL Y ASK + G ++L + L G+ Sbjct: 142 TKQVLKAGGMLERGTGRIVNIASTGGKQGLVHAAPYSASKHGVVGFTKALGLELARTGIT 201 Query: 181 LSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV 240 ++ + G V T V ++ + + F R + + V P EVAE+ Sbjct: 202 VNAVCPGFVETPMAASVREHYSDIWEVSTEEAFDRITARVPIGRYV------QPSEVAEM 255 Query: 241 --FLTALRAPKPTLRYFTTERFL 261 +L A T + L Sbjct: 256 VAYLIGPGAAAVTAQALNVCGGL 278 >1AE1-A nrPDB Length = 273 Score = 210 bits (534), Expect = 9e-55, Method: Composition-based stats. Identities = 53/266 (19%), Positives = 101/266 (37%), Gaps = 22/266 (8%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + T L+TG S GIG + LA ++ + ++L +W ++ Sbjct: 19 LKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREK------GLNV 72 Query: 61 ETLQLDV---RDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVV 117 E D+ + + V +G++++LV NAG+ + + E ++ N Sbjct: 73 EGSVCDLLSRTERDKLMQTVAHVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFE 132 Query: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 + Q P +K +G V+ S+ G LP +Y ASK A+ + +SLA Sbjct: 133 AAYHLSQIAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLACEWAKD 192 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV 237 + ++ + G + T +E + + + +I F + A P+EV Sbjct: 193 NIRVNSVAPGVILTPLVETAIK--KNPHQKEEIDNF---------IVKTPMGRAGKPQEV 241 Query: 238 AE--VFLTALRAPKPTLRYFTTERFL 261 + FL A T + + Sbjct: 242 SALIAFLCFPAASYITGQIIWADGGF 267 >4CQL-A nrPDB Length = 261 Score = 209 bits (533), Expect = 1e-54, Method: Composition-based stats. Identities = 65/265 (24%), Positives = 110/265 (41%), Gaps = 24/265 (9%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPP-GSLETLQ 64 L+TG SGIG ++VRLA + + + RL + PP G+ Q Sbjct: 14 ALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQ 73 Query: 65 LDVRDSKSVAAARERVTEG---RVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 DV ++++ E+V V+V AG+ L + ED V+ VN+ GT Sbjct: 74 ADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFL 133 Query: 122 MLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180 + QA + G G ++ S+ G +G Y ASK + GL ++ A L G+ Sbjct: 134 VTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIR 193 Query: 181 LSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV 240 + + G + T +KV P++V+D+ ++ + +PE+VA+V Sbjct: 194 CNSVLPGFIATPMTQKV---PQKVVDK--------------ITEMIPMGHLGDPEDVADV 236 Query: 241 --FLTALRAPKPTLRYFTTERFLPL 263 FL + + T L + Sbjct: 237 VAFLASEDSGYITGTSVEVTGGLFM 261 >3GRP-A nrPDB Length = 266 Score = 209 bits (533), Expect = 1e-54, Method: Composition-based stats. Identities = 61/266 (22%), Positives = 107/266 (40%), Gaps = 26/266 (9%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + L+TG + GIG +A + + ++ T D +L E A L Sbjct: 25 LTGRKALVTGATGGIGEAIARCFHAQGA-IVGLHGTRED-----KLKEIAADLGKDVFVF 78 Query: 61 ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 D + K +A ER EG +D+LV NAG+ G + + VL VN+ Sbjct: 79 SANLSDRKSIKQLAEVAEREMEG-IDILVNNAGITRDGLFVRMQDQDWDDVLAVNLTAAS 137 Query: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180 + + + M RR GR++ S+ G++G P YCA+K L G ++LA + + Sbjct: 138 TLTRELIHSMMRRRYGRIINITSIVGVVGNPGQTNYCAAKAGLIGFSKALAQEIASRNIT 197 Query: 181 LSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV--A 238 ++ I G + +A +K+ +E A + + EE+ A Sbjct: 198 VNCIAPGFIKSAMTDKLNEKQKE-----------------AIMAMIPMKRMGIGEEIAFA 240 Query: 239 EVFLTALRAPKPTLRYFTTERFLPLL 264 V+L + A T + + ++ Sbjct: 241 TVYLASDEAAYLTGQTLHINGGMAMI 266 >6NRP-A nrPDB Length = 263 Score = 209 bits (532), Expect = 1e-54, Method: Composition-based stats. Identities = 64/267 (23%), Positives = 104/267 (38%), Gaps = 31/267 (11%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 M R + L+TG S GIG +A++LA T+ Q + + + + Sbjct: 23 MTRRI-LVTGSSRGIGKAIALQLAKAGFDV-----TVHARSRQAEAEQVVQEIQALGQNS 76 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 L DV + ++V E+ E G +V NAGL G AL + V+ ++ G Sbjct: 77 HYLMFDVNERQTVQQILEQDVEQHGGFYGVVLNAGLTHDGAFPALTDQDWDEVISTSLDG 136 Query: 119 TVRMLQAFLPDMKR-RGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 +L+ + M R GR++ SV G+MG Y A+K L G ++LA+ L Sbjct: 137 FYNVLKPLIMPMIHLRKGGRIVTLSSVSGIMGNRGQVNYSAAKAGLIGATKALALELAKR 196 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV 237 + ++ + G + T V D H K + + +EV Sbjct: 197 KITVNCVAPGLIETEM----------VTDEVKEHAL----------KMIPLQRMGQVDEV 236 Query: 238 AEV--FLTALRAPKPTLRYFTTERFLP 262 A V FL + A T + + L Sbjct: 237 ASVVKFLCSDEASYVTRQVISVNGGLI 263 >2Q2Q-A nrPDB Length = 255 Score = 208 bits (530), Expect = 2e-54, Method: Composition-based stats. Identities = 59/244 (24%), Positives = 97/244 (39%), Gaps = 16/244 (6%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + L+TG +SGIGL +A LA + L G A +A Sbjct: 2 LKGKTALVTGSTSGIGLGIAQVLARAGANIV--------LNGFGDPAPALAEIARHGVKA 53 Query: 61 ETLQLDVRDSKSVAAARERVT--EGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 D+ D + A G VD+LV NAG+ + P+E ++ ++ +N+ Sbjct: 54 VHHPADLSDVAQIEALFALAEREFGGVDILVNNAGIQHVAPVEQFPLESWDKIIALNLSA 113 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 + LP M+ R GR++ SV GL+G Y A+K + GL + + + Sbjct: 114 VFHGTRLALPGMRARNWGRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGLETATSN 173 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 V + I G V T ++K + DR Q+ +++ A PE + Sbjct: 174 VTCNAICPGWVLTPLVQKQID------DRAANGGDPLQAQHDLLAEKQPSLAFVTPEHLG 227 Query: 239 EVFL 242 E+ L Sbjct: 228 ELVL 231 >2NM0-A nrPDB Length = 253 Score = 207 bits (526), Expect = 7e-54, Method: Composition-based stats. Identities = 70/265 (26%), Positives = 107/265 (40%), Gaps = 39/265 (14%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 M+R+V L+TG + GIGL +A A + Y + PP Sbjct: 20 MSRSV-LVTGGNRGIGLAIARAFADAGDKVAITYRS-----------------GEPPEGF 61 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 ++ D+ D++ V A + + E G V+VL+ NAG+ L + E+ SV++ N+ G Sbjct: 62 LAVKCDITDTEQVEQAYKEIEETHGPVEVLIANAGVTKDQLLMRMSEEDFTSVVETNLTG 121 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 T R+++ M R GRV++ SV GL+G Y ASK L G SLA L Sbjct: 122 TFRVVKRANRAMLRAKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARSLARELGSRN 181 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 + +++ G V T + + Q QV PEE+A Sbjct: 182 ITFNVVAPGFVDTDMTKVLTDE-----------------QRANIVSQVPLGRYARPEEIA 224 Query: 239 EV--FLTALRAPKPTLRYFTTERFL 261 FL + A T + L Sbjct: 225 ATVRFLASDDASYITGAVIPVDGGL 249 >5VT6-A nrPDB Length = 269 Score = 206 bits (525), Expect = 9e-54, Method: Composition-based stats. Identities = 58/264 (21%), Positives = 104/264 (39%), Gaps = 25/264 (9%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 A+ V +TG G+G ++ RL ++ D + + E + Sbjct: 24 AKRVAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWLMHE-----RDAGRDFK 78 Query: 62 TLQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGT 119 +DV D +S E+V G+VDVL+ NAG+ + + +V+ ++ Sbjct: 79 AYAVDVADFESCERCAEKVLADFGKVDVLINNAGITRDATFMKMTKGDWDAVMRTDLDAM 138 Query: 120 VRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGV 179 + + F+ M R GR++ GSV G G Y ++K + G ++LA+ G+ Sbjct: 139 FNVTKQFIAGMVERRFGRIVNIGSVNGSRGAFGQANYASAKAGIHGFTKTLALETAKRGI 198 Query: 180 HLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE 239 ++ + G + TA +E V P++VL+ Q+ P+EVA Sbjct: 199 TVNTVSPGYLATAMVEAV---PQDVLEAK-------------ILPQIPVGRLGRPDEVAA 242 Query: 240 --VFLTALRAPKPTLRYFTTERFL 261 FL + A T + Sbjct: 243 LIAFLCSDDAGFVTGADLAINGGM 266 >3AUT-A nrPDB Length = 269 Score = 206 bits (524), Expect = 1e-53, Method: Composition-based stats. Identities = 61/266 (22%), Positives = 106/266 (39%), Gaps = 25/266 (9%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + VV+ITG S+G+G +AVR + ++ Y + +A + + G Sbjct: 13 LKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINY-----YNNEEEALDAKKEVEEAGGQA 67 Query: 61 ETLQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 +Q DV + V + G +DV++ NAG+ P L D V+D N+ G Sbjct: 68 IIVQGDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTG 127 Query: 119 TVRMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 + + G V+ SV ++ P Y ASK ++ + E+LA+ P Sbjct: 128 AFLGSREAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPK 187 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV 237 G+ ++ I G ++T + P + R D+ + + PEEV Sbjct: 188 GIRVNNIGPGAMNTPINAEKFADP---VQRADVESM------------IPMGYIGKPEEV 232 Query: 238 AEV--FLTALRAPKPTLRYFTTERFL 261 A V FL + +A T + + Sbjct: 233 AAVAAFLASSQASYVTGITLFADGGM 258 >3W8F-A nrPDB Length = 260 Score = 205 bits (523), Expect = 2e-53, Method: Composition-based stats. Identities = 58/265 (21%), Positives = 106/265 (40%), Gaps = 15/265 (5%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKV-YATLRDLKTQGRLWEAARALACPPGS 59 + ++TG +SGIGL +A LA + + D++ + E+ Sbjct: 2 LKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESK-----FGVK 56 Query: 60 LETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVV 117 L D+ D+++ + E G +D+LV NAG+ P+E D +++ +N+ Sbjct: 57 AYYLNADLSDAQATRDFIAKAAEALGGLDILVNNAGIQHTAPIEEFPVDKWNAIIALNLS 116 Query: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 A LP M+++G GR++ S GL+ Y A+K + GL + A+ Sbjct: 117 AVFHGTAAALPIMQKQGWGRIINIASAHGLVASVNKSAYVAAKHGVVGLTKVTALENAGK 176 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV 237 G+ + I G V T +EK + + + PE++ Sbjct: 177 GITCNAICPGWVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQ-----PSLQFVTPEQL 231 Query: 238 --AEVFLTALRAPKPTLRYFTTERF 260 A VFL++ A + T + + Sbjct: 232 GGAAVFLSSAAADQMTGTTLSLDGG 256 >5YSS-A nrPDB Length = 256 Score = 205 bits (521), Expect = 3e-53, Method: Composition-based stats. Identities = 53/244 (21%), Positives = 99/244 (40%), Gaps = 16/244 (6%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + L+TG +SGIGL +A LA + L G + A A+A + Sbjct: 3 LTGKTALVTGSTSGIGLGIAQVLAQAGATLI--------LNGFGDVDAAKDAVAQYGKTP 54 Query: 61 ETLQLDVRDSKSVAAARE--RVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 D+ D +A G VD+L+ NAG+ + P+E D +++ +N+ Sbjct: 55 GYHGADLSDEAQIADMMRYAESEFGGVDILINNAGIQHVSPIETFPVDKWNAIIAINLSS 114 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 + LP M+ R GR++ SV GL+ Y A+K + GL +++A+ Sbjct: 115 VFHTTRLALPGMRARNWGRIINIASVHGLVASKEKSAYVAAKHGVVGLTKTIALETAQTE 174 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 + + + G V T ++ +++ R + +++ PE++ Sbjct: 175 ITCNALCPGWVLTPLVQ------QQIDKRIAEGAEPEAARDALLAEKQPSREFVTPEQLG 228 Query: 239 EVFL 242 + L Sbjct: 229 NLAL 232 >3T7C-A nrPDB Length = 299 Score = 205 bits (521), Expect = 3e-53, Method: Composition-based stats. Identities = 64/279 (22%), Positives = 110/279 (39%), Gaps = 22/279 (7%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLR------DLKTQGRLWEAARALA 54 + V ITG + G G A+ LA + + + + + T L E R + Sbjct: 26 VEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETVRQVE 85 Query: 55 CPPGSLETLQLDVRDSKSVAAARE--RVTEGRVDVLVCNAGLGLLGP-LEALGEDAVASV 111 + Q+DVRD ++ AA + GR+D+++ NA L G L + + Sbjct: 86 ALGRRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRMDPKTWRDM 145 Query: 112 LDVNVVGTVRMLQAFLPD-MKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170 +DVN+ G + +P M + G ++ T S+GGL G Y ASK L GL ++ Sbjct: 146 IDVNLNGAWITARVAIPHIMAGKRGGSIVFTSSIGGLRGAENIGNYIASKHGLHGLMRTM 205 Query: 171 AVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFH----RFYQYLAHSKQV 226 A+ L P + ++++ V T +L P + R D+ + H + Sbjct: 206 ALELGPRNIRVNIVCPSSVATPM---LLNEPTYRMFRPDLENPTVEDFQVASRQMHVLPI 262 Query: 227 FREAAQNPEEVAEV--FLTALRAPKPTLRYFTTERFLPL 263 P +++ FL + A T + L Sbjct: 263 P---YVEPADISNAILFLVSDDARYITGVSLPVDGGALL 298 >1GEG-A nrPDB Length = 256 Score = 204 bits (519), Expect = 4e-53, Method: Composition-based stats. Identities = 67/266 (25%), Positives = 112/266 (42%), Gaps = 17/266 (6%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 62 + V L+TG GIG +A+RL D A + G Sbjct: 2 KKVALVTGAGQGIGKAIALRLVKDGFAVAIADYN------DATAKAVASEINQAGGHAVA 55 Query: 63 LQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 +++DV D V AA E+ T G DV+V NAG+ P+E++ + V V ++NV G + Sbjct: 56 VKVDVSDRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVI 115 Query: 121 RMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGV 179 +QA + K+ G G+++ S G +G P VY +SKFA+ GL ++ A L P G+ Sbjct: 116 WGIQAAVEAFKKEGHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGI 175 Query: 180 HLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE 239 ++ G V T ++ E + + F + + PE+VA Sbjct: 176 TVNGYCPGIVKTPMWAEIDRQVSEAAGKPLGYGTAEFAKRIT------LGRLSEPEDVAA 229 Query: 240 --VFLTALRAPKPTLRYFTTERFLPL 263 +L + + T + + + Sbjct: 230 CVSYLASPDSDYMTGQSLLIDGGMVF 255 >1GEE-A nrPDB Length = 261 Score = 204 bits (518), Expect = 6e-53, Method: Composition-based stats. Identities = 57/268 (21%), Positives = 102/268 (38%), Gaps = 25/268 (9%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + VV+ITG S+G+G +A+R A++ ++ Y + D + G Sbjct: 5 LEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKED-----EANSVLEEIKKVGGEA 59 Query: 61 ETLQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 ++ DV V + G++DV++ NAGL + V+D N+ G Sbjct: 60 IAVKGDVTVESDVINLVQSAIKEFGKLDVMINNAGLENPVSSHEMSLSDWNKVIDTNLTG 119 Query: 119 TVRMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 + + G V+ SV + P Y ASK ++ + E+LA+ P Sbjct: 120 AFLGSREAIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALEYAPK 179 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV 237 G+ ++ I G ++T + PE+ R D+ + + PEE+ Sbjct: 180 GIRVNNIGPGAINTPINAEKFADPEQ---RADVESM------------IPMGYIGEPEEI 224 Query: 238 AEVFLT--ALRAPKPTLRYFTTERFLPL 263 A V + A T + + L Sbjct: 225 AAVAAWLASSEASYVTGITLFADGGMTL 252 >3V2H-A nrPDB Length = 281 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 62/264 (23%), Positives = 111/264 (42%), Gaps = 13/264 (4%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 M +ITG +SGIGL +A LA + D + + E A G++ Sbjct: 23 MMTKTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPD-EIRTVTDEVA---GLSSGTV 78 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 D+ +A V + G D+LV NAG+ + +E + ++ VN+ Sbjct: 79 LHHPADMTKPSEIADMMAMVADRFGGADILVNNAGVQFVEKIEDFPVEQWDRIIAVNLSS 138 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 + ++ +P MK++G GR++ S GL+ PF Y A+K + GL +++A+ + G Sbjct: 139 SFHTIRGAIPPMKKKGWGRIINIASAHGLVASPFKSAYVAAKHGIMGLTKTVALEVAESG 198 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 V ++ I G V T +EK + T+ + K + E+VA Sbjct: 199 VTVNSICPGYVLTPLVEKQIPDQARTRGITEEQVINEVM-----LKGQPTKKFITVEQVA 253 Query: 239 E--VFLTALRAPKPTLRYFTTERF 260 ++L A + T + + + Sbjct: 254 SLALYLAGDDAAQITGTHVSMDGG 277 >2GDZ-A nrPDB Length = 267 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 67/269 (24%), Positives = 106/269 (39%), Gaps = 32/269 (11%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 62 V L+TG + GIG A L ++ V L G +AA P Sbjct: 7 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLE----AGVQCKAALHEQFEPQKTLF 62 Query: 63 LQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 +Q DV D + + +V + GR+D+LV NAG+ E L +N+V + Sbjct: 63 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNN--------EKNWEKTLQINLVSVI 114 Query: 121 RMLQAFLPDMKRRGSGR---VLVTGSVGGLMGLPFNDVYCASKFALEGLCES--LAVLLL 175 L M ++ G ++ S+ GLM + VYCASK + G S LA L+ Sbjct: 115 SGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLM 174 Query: 176 PFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFR-EAAQNP 234 GV L+ I G V+TA +E + ++ +Y H K + + +P Sbjct: 175 NSGVRLNAICPGFVNTAILESI----------EKEENMGQYIEYKDHIKDMIKYYGILDP 224 Query: 235 EEVAEVFLTALRAPKPTLRY--FTTERFL 261 +A +T + TT + + Sbjct: 225 PLIANGLITLIEDDALNGAIMKITTSKGI 253 >4CQM-B nrPDB Length = 244 Score = 202 bits (514), Expect = 2e-52, Method: Composition-based stats. Identities = 60/263 (22%), Positives = 97/263 (36%), Gaps = 31/263 (11%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETL 63 V + G S GIG +A +A + + L K G Sbjct: 10 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAA---------GDLGGDHLAF 60 Query: 64 QLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 DV V E + + GRV+ LV AG+ G L + + S L N++G++ Sbjct: 61 SCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSML 120 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 +A + M ++ G ++ GS+ GL G VY ASK L G +LA + + + Sbjct: 121 TCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRV 180 Query: 182 SLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVF 241 +++ G VHT + + EE L + + EVA Sbjct: 181 NVVAPGFVHTDMTKDL---KEEHLKK-----------------NIPLGRFGETIEVAHAV 220 Query: 242 LTALRAPKPTLRYFTTERFLPLL 264 + L +P T + L L+ Sbjct: 221 VFLLESPYITGHVLVVDGGLQLI 243 >3O4R-A nrPDB Length = 261 Score = 202 bits (513), Expect = 2e-52, Method: Composition-based stats. Identities = 62/267 (23%), Positives = 106/267 (39%), Gaps = 26/267 (9%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 +A V L+T + GIG +A RLA D + + Q + +A L S+ Sbjct: 13 LANKVALVTASTDGIGFAIARRLAQDGAHVVV------SSRKQQNVDQAVATLQGEGLSV 66 Query: 61 ETLQLDVRDSKSVAAARERVT--EGRVDVLVCNAGLGLL-GPLEALGEDAVASVLDVNVV 117 V ++ G +D+LV NA + G + + E+ LD+NV Sbjct: 67 TGTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVK 126 Query: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 M +A +P+M++RG G V++ S+ P Y SK AL GL ++LA+ L P Sbjct: 127 APALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPR 186 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV 237 + ++ + G + T+F + +D+ + + + PE+ Sbjct: 187 NIRVNCLAPGLIKTSFSRMLW------MDKEKEESMK---------ETLRIRRLGEPEDC 231 Query: 238 AEV--FLTALRAPKPTLRYFTTERFLP 262 A + FL + A T P Sbjct: 232 AGIVSFLCSEDASYITGETVVVGGGTP 258 >2AE2-A nrPDB Length = 260 Score = 202 bits (513), Expect = 2e-52, Method: Composition-based stats. Identities = 52/267 (19%), Positives = 99/267 (37%), Gaps = 23/267 (8%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + L+TG S GIG + LAS + + ++L W + + Sbjct: 7 LEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSK------GFKV 60 Query: 61 ETLQLDVRDSKSVAAARERVT---EGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVV 117 E D+ V G++++LV NAG+ + + + + ++ +N Sbjct: 61 EASVCDLSSRSERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINFE 120 Query: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 + P +K G V+ SV G + +P+ VY A+K A++ L LA Sbjct: 121 AAYHLSVLAHPFLKASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAFEWAKD 180 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV 237 + ++ + G + T+ +E + PE+ ++ A P+E+ Sbjct: 181 NIRVNGVGPGVIATSLVEMTIQDPEQ------KENLNKLIDRCA------LRRMGEPKEL 228 Query: 238 AEV--FLTALRAPKPTLRYFTTERFLP 262 A + FL A T + + L Sbjct: 229 AAMVAFLCFPAASYVTGQIIYVDGGLM 255 >3WTC-A nrPDB Length = 262 Score = 201 bits (511), Expect = 4e-52, Method: Composition-based stats. Identities = 59/268 (22%), Positives = 111/268 (41%), Gaps = 17/268 (6%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 ++ + +TG + GIG +A+RLA D + + Q L E A+ + Sbjct: 6 LSGKIAAVTGAAQGIGKAIALRLAKDGADVILLDV------KQDTLAETAKEVEALGRRA 59 Query: 61 ETLQLDVRDSKSVAA--ARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 L D+ + + A T G +D++V NAG+ + P+ + + + +NV G Sbjct: 60 VALTADISNRDQFRSTLADAAKTLGGLDIMVNNAGICQVKPILDIEPAEIEKIFSINVQG 119 Query: 119 TVRMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 + +QA K +G G+++ S+ G G P Y A+KFA+ L +S A L Sbjct: 120 VLWGMQAAATLFKEKGTKGKIINACSIAGHEGYPLLGAYSATKFAVRALTQSAAKELASS 179 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV 237 G+ ++ G V T + E+ T+ ++ + +A + ++V Sbjct: 180 GITVNSYCPGIVGTDMWVTIDKRMAEITGTEIGATYKKYVEGIA------LGRVETADDV 233 Query: 238 AE--VFLTALRAPKPTLRYFTTERFLPL 263 A +L++ A T + + L Sbjct: 234 AGFVAYLSSSDADYMTGQSVLIDGGLVF 261 >4IIV-A nrPDB Length = 267 Score = 199 bits (507), Expect = 1e-51, Method: Composition-based stats. Identities = 61/267 (22%), Positives = 105/267 (39%), Gaps = 29/267 (10%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 M+R+V L+TG S GIG +A +LA+D Y + E A+ G+ Sbjct: 25 MSRSV-LVTGASKGIGRAIARQLAADGFNIGVHYH-----RDAAGAQETLNAIVANGGNG 78 Query: 61 ETLQLDVRDSKSVAAARER--VTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 L DV + + E G +V NAG+ AL D +V+ N+ Sbjct: 79 RLLSFDVANREQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPALSNDDWDAVIHTNLDS 138 Query: 119 TVRMLQAF-LPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 ++Q +P + R GR++ SV G+MG Y A+K + G ++LA+ L Sbjct: 139 FYNVIQPCIMPMIGARQGGRIITLSSVSGVMGNRGQVNYSAAKAGIIGATKALAIELAKR 198 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV 237 + ++ I G + T +E + +E + + + EEV Sbjct: 199 KITVNCIAPGLIDTGMIEMEESALKEAMS------------------MIPMKRMGQAEEV 240 Query: 238 AEV--FLTALRAPKPTLRYFTTERFLP 262 A + +L + A T + + + Sbjct: 241 AGLASYLMSDIAGYVTRQVISINGGML 267 >5B1Y-A nrPDB Length = 270 Score = 197 bits (502), Expect = 4e-51, Method: Composition-based stats. Identities = 73/266 (27%), Positives = 107/266 (40%), Gaps = 25/266 (9%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 M T L+TG S GIG +R A + Y + DL + E AR L P Sbjct: 21 METTYALVTGGSRGIGRATVLRFAREGWSVVIAYKSRADL--AEKTAEEARRLGSP--EA 76 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 T+++DV D SV RV E ++VLV AG+ LG +E L VN+ G Sbjct: 77 YTVRVDVGDPDSVTEMSSRVGELIPHLNVLVNAAGVLQLGGIEETSISEWEETLRVNLTG 136 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLP-FNDVYCASKFALEGLCESLAVLLLPF 177 + + LP +++ ++ S+ G G Y ASK + GL + LAV L + Sbjct: 137 VYLVTKLLLPLLRKAKWASIVNVASIAGETGNVVAGVAYSASKAGVIGLTKRLAVQLAGY 196 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV 237 G+ ++ + V T L +PE+ R I + H L PE+V Sbjct: 197 GIRVNAVAPSFVETDMTRSFLDTPEK---RERIASLHPLKIIL------------KPEDV 241 Query: 238 AEVFLTAL---RAPKPTLRYFTTERF 260 AE L R+ T + Sbjct: 242 AEAILFLADPRRSRGITGHVLSINAG 267 >1X1T-A nrPDB Length = 260 Score = 197 bits (502), Expect = 4e-51, Method: Composition-based stats. Identities = 60/265 (22%), Positives = 105/265 (39%), Gaps = 15/265 (5%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPG-S 59 + V ++TG +SGIGL +A LA+ + L + + LA G Sbjct: 2 LKGKVAVVTGSTSGIGLGIATALAAQGADIV-----LNGFGDAAEIEKVRAGLAAQHGVK 56 Query: 60 LETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVV 117 + D+ ++V + GR+D+LV NAG+ +E + ++L +N+ Sbjct: 57 VLYDGADLSKGEAVRGLVDNAVRQMGRIDILVNNAGIQHTALIEDFPTEKWDAILALNLS 116 Query: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 A LP MK++G GR++ S GL+ Y A+K + G + A+ Sbjct: 117 AVFHGTAAALPHMKKQGFGRIINIASAHGLVASANKSAYVAAKHGVVGFTKVTALETAGQ 176 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV 237 G+ + I G V T +EK + + E S++ PE++ Sbjct: 177 GITANAICPGWVRTPLVEKQISALAEKNGVDQETAARELL-----SEKQPSLQFVTPEQL 231 Query: 238 A--EVFLTALRAPKPTLRYFTTERF 260 VFL + A + T + + Sbjct: 232 GGTAVFLASDAAAQITGTTVSVDGG 256 >3UVE-A nrPDB Length = 286 Score = 197 bits (500), Expect = 7e-51, Method: Composition-based stats. Identities = 59/208 (28%), Positives = 96/208 (46%), Gaps = 14/208 (6%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYA----------TLRDLKTQGRLWEAA 50 + V +TG + G G AVRLA + + V T T L E A Sbjct: 9 VEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDLAETA 68 Query: 51 RALACPPGSLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLG-PLEALGEDA 107 + + T ++DVRD ++ AA + E GR+D++V NAG+G G L+ E+ Sbjct: 69 DLVKGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNGGDTLDKTSEED 128 Query: 108 VASVLDVNVVGTVRMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGL 166 ++D+N+ G + ++A +P M G G +++T SVGGL P Y A+K + GL Sbjct: 129 WTEMIDINLAGVWKTVKAGVPHMIAGGRGGSIILTSSVGGLKAYPHTGHYVAAKHGVVGL 188 Query: 167 CESLAVLLLPFGVHLSLIECGPVHTAFM 194 + V L + ++ + V T + Sbjct: 189 MRAFGVELGQHMIRVNSVHPTHVKTPML 216 >2EW8-A nrPDB Length = 249 Score = 195 bits (496), Expect = 2e-50, Method: Composition-based stats. Identities = 63/263 (23%), Positives = 103/263 (39%), Gaps = 23/263 (8%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + + +ITG ++GIG +A R A + + EA A+ + Sbjct: 5 LKDKLAVITGGANGIGRAIAERFAVEGADIAIADLVPAP--------EAEAAIRNLGRRV 56 Query: 61 ETLQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 T++ DV V A ++V T GR D+LV NAG+ L P + L + ++NV Sbjct: 57 LTVKCDVSQPGDVEAFGKQVISTFGRCDILVNNAGIYPLIPFDELTFEQWKKTFEINVDS 116 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 M +AF+P MKR G GR++ S + + Y ++K A G +LA L G Sbjct: 117 GFLMAKAFVPGMKRNGWGRIINLTSTTYWLKIEAYTHYISTKAANIGFTRALASDLGKDG 176 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 + ++ I V TA E + + D + L + A Sbjct: 177 ITVNAIAPSLVRTATTEA--SALSAMFDVLP--NMLQAIPRLQVPLDLTG---------A 223 Query: 239 EVFLTALRAPKPTLRYFTTERFL 261 FL + A T + + + Sbjct: 224 AAFLASDDASFITGQTLAVDGGM 246 >2CFC-A nrPDB Length = 250 Score = 195 bits (496), Expect = 2e-50, Method: Composition-based stats. Identities = 58/204 (28%), Positives = 87/204 (42%), Gaps = 10/204 (4%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETL 63 V ++TG SSG GL +A R + + + + L+ R + + Sbjct: 3 RVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTH-----WHAYADKVLRV 57 Query: 64 QLDVRDSKSVAAARERVTE--GRVDVLVCNAGLG---LLGPLEALGEDAVASVLDVNVVG 118 + DV D V AA E G +DVLV NAG+ G L + V+ VNV G Sbjct: 58 RADVADEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVRG 117 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 +A LP M +G+G ++ SV L+ P Y SK A+ L +S+AV G Sbjct: 118 IFLGCRAVLPHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDYAGSG 177 Query: 179 VHLSLIECGPVHTAFMEKVLGSPE 202 + + + G + T + L PE Sbjct: 178 IRCNAVCPGMIETPMTQWRLDQPE 201 >3V2G-A nrPDB Length = 271 Score = 195 bits (495), Expect = 3e-50, Method: Composition-based stats. Identities = 54/217 (24%), Positives = 90/217 (41%), Gaps = 10/217 (4%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 +A +TG S GIG +A RLA + + Y + R + G Sbjct: 29 LAGKTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAE-----RAQAVVSEIEQAGGRA 83 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 ++ D RD++++ A E G +D+LV +AG+ PLE V+ VN Sbjct: 84 VAIRADNRDAEAIEQAIRETVEALGGLDILVNSAGIWHSAPLEETTVADFDEVMAVNFRA 143 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGS-VGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 +++ + GR++ GS + L+ P +Y ASK AL GL + LA L P Sbjct: 144 PFVAIRSASRHLGD--GGRIITIGSNLAELVPWPGISLYSASKAALAGLTKGLARDLGPR 201 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFH 214 G+ ++++ G T E +R ++ Sbjct: 202 GITVNIVHPGSTDTDMNPADGDHAEAQRERIATGSYG 238 >5OVL-A nrPDB Length = 300 Score = 194 bits (494), Expect = 3e-50, Method: Composition-based stats. Identities = 66/260 (25%), Positives = 103/260 (39%), Gaps = 38/260 (14%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 VL+TG + GIGL +A RLA+D + + + P L +Q Sbjct: 71 VLVTGGNRGIGLAIARRLAADGHKVAVTHRG-----------------SGAPDDLFGVQC 113 Query: 66 DVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRML 123 DV DS +V A + V E G V+VLV NAG+ L + E+ V++ N+ G R Sbjct: 114 DVTDSAAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCA 173 Query: 124 QAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSL 183 Q M+R+ GR++ GSV G+ G+ Y A+K L G+ S++ L GV ++ Sbjct: 174 QRASRTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANV 233 Query: 184 IECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV--F 241 + G + T + + + EEVA F Sbjct: 234 VAPGYIDTEMTRALDER-----------------IQAGALDFIPAKRVGTAEEVAGAVSF 276 Query: 242 LTALRAPKPTLRYFTTERFL 261 L + A + + Sbjct: 277 LASEDASYIAGAVIPVDGGM 296 >3WYE-A nrPDB Length = 256 Score = 194 bits (494), Expect = 3e-50, Method: Composition-based stats. Identities = 65/266 (24%), Positives = 111/266 (41%), Gaps = 17/266 (6%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 62 + V L+TG GIG +A+RL D A + G Sbjct: 2 KKVALVTGAGQGIGKAIALRLVKDGFAVAIADYN------DATAKAVASEINQAGGHAVA 55 Query: 63 LQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 +++DV D V AA E+ T G DV+V NAG+ + PL + E+ + + VNV Sbjct: 56 VKVDVSDRDQVFAAVEQARKTLGGFDVIVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVF 115 Query: 121 RMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGV 179 +QA + K+ G G+++ S+ + G P Y +KFA+ GL ++ A L P G+ Sbjct: 116 FGIQAAVEAFKKEGHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAARDLAPLGI 175 Query: 180 HLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE 239 ++ G V T E++ ++ + F + +A + PE+VA Sbjct: 176 TVNGYCPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRP------SVPEDVAG 229 Query: 240 V--FLTALRAPKPTLRYFTTERFLPL 263 + FL + + T + + + Sbjct: 230 LVSFLASPDSDYMTGQSLLIDGGMVF 255 >1YXM-A nrPDB Length = 303 Score = 194 bits (493), Expect = 4e-50, Method: Composition-based stats. Identities = 56/282 (19%), Positives = 109/282 (38%), Gaps = 23/282 (8%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + V ++TG ++GIG + L S L LK+ + A + Sbjct: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQ-ANLPPTKQARV 74 Query: 61 ETLQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 +Q ++R+ + V + T G+++ LV N G L P E + +VL+ N+ G Sbjct: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 T M +A + G ++ V G P A++ + L +SLA+ G Sbjct: 135 TFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQ--YLAHSKQVFREAAQNPEE 236 + ++ + G +++ +T + + + Q + +++ + PEE Sbjct: 194 IRINCVAPGVIYS---------------QTAVENYGSWGQSFFEGSFQKIPAKRIGVPEE 238 Query: 237 VAEV--FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNY 276 V+ V FL + A T + + L + P N+ Sbjct: 239 VSSVVCFLLSPAASFITGQSVDVDGGRSLYTHSYEVPDHDNW 280 >2ZAT-A nrPDB Length = 260 Score = 193 bits (490), Expect = 1e-49, Method: Composition-based stats. Identities = 68/265 (25%), Positives = 105/265 (39%), Gaps = 26/265 (9%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + V L+T + GIGL +A RLA D + + Q + L S+ Sbjct: 12 LENKVALVTASTDGIGLAIARRLAQDGAHVVV------SSRKQENVDRTVATLQGEGLSV 65 Query: 61 ETLQLDVRDSKSVAAARERVT--EGRVDVLVCNAGLGLL-GPLEALGEDAVASVLDVNVV 117 V ++ G VD+LV NA + G + E+ +L VNV Sbjct: 66 TGTVCHVGKAEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVK 125 Query: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 TV M +A +P+M++RG G VL+ SVG P Y SK AL GL ++LAV L P Sbjct: 126 ATVLMTKAVVPEMEKRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAPR 185 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV 237 + ++ + G + T F + + +D+ + + NPE+ Sbjct: 186 NIRVNCLAPGLIKTNFSQVLW------MDKARKEYMK---------ESLRIRRLGNPEDC 230 Query: 238 AEV--FLTALRAPKPTLRYFTTERF 260 A + FL + A T Sbjct: 231 AGIVSFLCSEDASYITGETVVVGGG 255 >4IS3-A nrPDB Length = 268 Score = 192 bits (489), Expect = 1e-49, Method: Composition-based stats. Identities = 56/241 (23%), Positives = 97/241 (40%), Gaps = 23/241 (9%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETL 63 V +ITG + GIG A + ++ T ++ T + P + Sbjct: 26 KVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKEL----YPEEEVLGF 81 Query: 64 QLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 D+ +V AA +V GR+DV++ NAG+ + E+ ++D+NV G Sbjct: 82 APDLTSRDAVMAAVGQVAQKYGRLDVMINNAGITSNNVFSRVSEEEFKHIMDINVTGVFN 141 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 MK G ++ T SV G+ G Y ASK ++ GL L ++ + + Sbjct: 142 GAWCAYQCMKDAKKGVIINTASVTGIFGSLSGVGYPASKASVIGLTHGLGREIIRKNIRV 201 Query: 182 SLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVF 241 + G V+T G+P E+++ + K + + PEE+A V+ Sbjct: 202 VGVAPGVVNTDMTN---GNPPEIME--------------GYLKALPMKRMLEPEEIANVY 244 Query: 242 L 242 L Sbjct: 245 L 245 >1NFF-A nrPDB Length = 260 Score = 192 bits (488), Expect = 2e-49, Method: Composition-based stats. Identities = 63/264 (23%), Positives = 103/264 (39%), Gaps = 35/264 (13%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + V L++G + G+G + ++ ++ E A + Sbjct: 5 LTGKVALVSGGARGMGASHVRAMVAEGAKVVFGDIL---------DEEGKAMAAELADAA 55 Query: 61 ETLQLDVRDSKSVAAARERVT--EGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 + LDV AA + G + VLV NAG+ +G +E +LDVN+ G Sbjct: 56 RYVHLDVTQPAQWKAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLTG 115 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 ++A + MK G G ++ S+ GL G Y A+KFA+ GL +S A+ L P G Sbjct: 116 VFLGIRAVVKPMKEAGRGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTALELGPSG 175 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 + ++ I G V T + V PE++ Q A P EV+ Sbjct: 176 IRVNSIHPGLVKTPMTDWV---PEDIF-------------------QTALGRAAEPVEVS 213 Query: 239 E--VFLTALRAPKPTLRYFTTERF 260 V+L + + T F + Sbjct: 214 NLVVYLASDESSYSTGAEFVVDGG 237 >5OVJ-A nrPDB Length = 256 Score = 190 bits (484), Expect = 4e-49, Method: Composition-based stats. Identities = 66/260 (25%), Positives = 103/260 (39%), Gaps = 38/260 (14%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 VL+TG + GIGL +A RLA+D + + + P L +Q Sbjct: 27 VLVTGGNRGIGLAIARRLAADGHKVAVTHRG-----------------SGAPDDLFGVQC 69 Query: 66 DVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRML 123 DV DS +V A + V E G V+VLV NAG+ L + E+ V++ N+ G R Sbjct: 70 DVTDSAAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCA 129 Query: 124 QAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSL 183 Q M+R+ GR++ GSV G+ G+ Y A+K L G+ S++ L GV ++ Sbjct: 130 QRASRTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANV 189 Query: 184 IECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV--F 241 + G + T + + + EEVA F Sbjct: 190 VAPGYIDTEMTRALDER-----------------IQAGALDFIPAKRVGTAEEVAGAVSF 232 Query: 242 LTALRAPKPTLRYFTTERFL 261 L + A + + Sbjct: 233 LASEDASYIAGAVIPVDGGM 252 >5EJ2-A nrPDB Length = 308 Score = 190 bits (484), Expect = 5e-49, Method: Composition-based stats. Identities = 69/277 (24%), Positives = 117/277 (42%), Gaps = 18/277 (6%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYAT------LRDLKTQGRLWEAARALA 54 +A V I+G + G G AVRLA + + + T L E A + Sbjct: 35 VAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETADLVK 94 Query: 55 CPPGSLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGP-LEALGEDAVASV 111 + T Q+DVRD +++ +A + E GR+D++V NAG+G G L + ++ + Sbjct: 95 DLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTDGRKLHKIRDNVWQDM 154 Query: 112 LDVNVVGTVRMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170 +D+N+ G ++A +P + G G +++T SVGG P Y A+K + GL + Sbjct: 155 IDINLTGVWHTVKAGVPHVLSGGRGGSIVLTSSVGGRKAYPNTGHYIAAKHGVIGLMRAF 214 Query: 171 AVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHR----FYQYLAHSKQV 226 AV L P + ++ + V T V+ L R D+ + H+ V Sbjct: 215 AVELGPHMIRVNAVLPTQVSTTM---VMNDQTFRLFRPDLENPGPDDFAPISQMMHTLPV 271 Query: 227 FREAAQNPEEVAEVFLTALRAPKPTLRYFTTERFLPL 263 A + A +FL + + T + L Sbjct: 272 PWVDASDISN-AVLFLASDESRYVTGVSLPVDAGSLL 307 >4RZI-B nrPDB Length = 240 Score = 190 bits (484), Expect = 6e-49, Method: Composition-based stats. Identities = 55/240 (22%), Positives = 97/240 (40%), Gaps = 35/240 (14%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + V+++TG + GIG + L ++ DL T G E Sbjct: 6 LEDKVIVVTGGNRGIGAAIVKLLQEMGAKVAFT-----DLATDGGNTE-----------A 49 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 + +V D +S+ AA +T+ G V +V NAG+ L +VL+VN+ G Sbjct: 50 LGVVANVTDLESMTAAAAEITDKLGPVYGVVANAGITKDNFFPKLTPADWDAVLNVNLKG 109 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 ++ F+ M R +G ++ S+ G G Y A+K + G+ +SLA +G Sbjct: 110 VAYSIKPFIEGMYERKAGSIVAISSISGERGNVGQTNYSATKAGVIGMMKSLAREGARYG 169 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 V + + G + T L E++ ++ +K++ PEE+A Sbjct: 170 VRANAVAPGFIDTEMT---LAIREDIREK--------------ITKEIPFRRFGKPEEIA 212 >4IIN-A nrPDB Length = 271 Score = 189 bits (481), Expect = 1e-48, Method: Composition-based stats. Identities = 50/266 (18%), Positives = 85/266 (31%), Gaps = 26/266 (9%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 VLITG S GIG +A LAS + + Y + L Sbjct: 28 TGKNVLITGASKGIGAEIAKTLASMGLKVWINYRS-----NAEVADALKNELEEKGYKAA 82 Query: 62 TLQLDVRDSKSVAAARERVT--EGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGT 119 ++ D A + + +G + LV NAG+ + + V+D N+ Sbjct: 83 VIKFDAASESDFIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLTSA 142 Query: 120 VRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGV 179 + L M + G V+ S+ G G Y ASK + + +S A + Sbjct: 143 FIGCREALKVMSKSRFGSVVNVASIIGERGNMGQTNYSASKGGMIAMSKSFAYEGALRNI 202 Query: 180 HLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE 239 + + G + T + + + K + + +EVAE Sbjct: 203 RFNSVTPGFIETDMNANLKDELKA-----------------DYVKNIPLNRLGSAKEVAE 245 Query: 240 --VFLTALRAPKPTLRYFTTERFLPL 263 FL + + T L + Sbjct: 246 AVAFLLSDHSSYITGETLKVNGGLYM 271 >5U9P-A nrPDB Length = 265 Score = 189 bits (480), Expect = 2e-48, Method: Composition-based stats. Identities = 50/202 (24%), Positives = 81/202 (40%), Gaps = 8/202 (3%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + LITG GIGL LA LA + + + AR + Sbjct: 18 LDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRN------EEKAATLARRFRDEGFAA 71 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 + DV + V AA + G +D+LV NAG+ PL+A D +++ VN+ G Sbjct: 72 DHAVFDVAEHAQVRAAIDEFEARVGAIDILVNNAGIQRRAPLDAFEPDDWHALMRVNLDG 131 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 + QA M RG G+++ SV + P Y A+K A+ L + + +G Sbjct: 132 VFNVAQAVARHMIARGHGKIINICSVQSELARPTIAPYAATKGAVRMLTKGMCADWARYG 191 Query: 179 VHLSLIECGPVHTAFMEKVLGS 200 + + + G T ++ Sbjct: 192 IQANGLAPGYFETELNRALVDD 213 >3A28-C nrPDB Length = 258 Score = 189 bits (479), Expect = 2e-48, Method: Composition-based stats. Identities = 60/264 (22%), Positives = 109/264 (41%), Gaps = 15/264 (5%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETL 63 V ++TG + GIG ++ +LA+D + + + E + + + Sbjct: 3 KVAMVTGGAQGIGRGISEKLAADGFDIAVADLP----QQEEQAAETIKLIEAADQKAVFV 58 Query: 64 QLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 LDV D + +A + E G DVLV NAG+ + PL + E+ + + VNV Sbjct: 59 GLDVTDKANFDSAIDEAAEKLGGFDVLVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFF 118 Query: 122 MLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180 +QA G G+++ S+ + G P Y +KFA+ GL ++ A L P G Sbjct: 119 GIQAASRKFDELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQELAPKGHT 178 Query: 181 LSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV 240 ++ G V T E++ ++ + F + +A + PE+VA + Sbjct: 179 VNAYAPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRP------SVPEDVAGL 232 Query: 241 --FLTALRAPKPTLRYFTTERFLP 262 FL + + T + + + Sbjct: 233 VSFLASENSNYVTGQVMLVDGGML 256 >1UZM-A nrPDB Length = 247 Score = 188 bits (477), Expect = 3e-48, Method: Composition-based stats. Identities = 68/260 (26%), Positives = 107/260 (41%), Gaps = 38/260 (14%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 VL+TG + GIGL +A RLA+D + + + P L +++ Sbjct: 18 VLVTGGNRGIGLAIAQRLAADGHKVAVTHRG-----------------SGAPKGLFGVEV 60 Query: 66 DVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRML 123 DV DS +V A V E G V+VLV NAGL L + E+ V++ N+ G R+ Sbjct: 61 DVTDSDAVDRAFTAVEEHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVA 120 Query: 124 QAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSL 183 Q M+R GR++ GSV GL G+ Y ASK + G+ S+A L V ++ Sbjct: 121 QRASRSMQRNKFGRMIFIGSVSGLWGIGNQANYAASKAGVIGMARSIARELSKANVTANV 180 Query: 184 IECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV--F 241 + G + T + ++ + + + P EVA V F Sbjct: 181 VAPGYIDTDMTRALDERIQQ-----------------GALQFIPAKRVGTPAEVAGVVSF 223 Query: 242 LTALRAPKPTLRYFTTERFL 261 L + A + + + Sbjct: 224 LASEDASYISGAVIPVDGGM 243 >4Z9Y-A nrPDB Length = 253 Score = 187 bits (476), Expect = 5e-48, Method: Composition-based stats. Identities = 47/220 (21%), Positives = 83/220 (37%), Gaps = 11/220 (5%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + V LITGC +G+G +A+ LA V + + Sbjct: 8 LQGKVALITGCDTGLGQGMAIGLAQAGCDIVGVNIV--------EPKDTIEKVTALGRRF 59 Query: 61 ETLQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 +L D+ + A E+ G VD+LV NAG+ E V+++N+ Sbjct: 60 LSLTADMSNVSGHAELVEKAVAEFGHVDILVNNAGIIRREDAIEFSEKNWDDVMNLNIKS 119 Query: 119 TVRMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 M Q ++G G+++ S+ G Y ASK A+ G+ +A Sbjct: 120 VFFMSQTVARQFIKQGKGGKIINIASMLSFQGGIRVPSYTASKSAVMGVTRLMANEWAKH 179 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFY 217 G++++ I G + T +++ E + D R+ Sbjct: 180 GINVNAIAPGYMATNNTQQLRADEERSKEILDRIPAGRWG 219 >1CYD-A nrPDB Length = 244 Score = 186 bits (472), Expect = 1e-47, Method: Composition-based stats. Identities = 52/214 (24%), Positives = 92/214 (42%), Gaps = 13/214 (6%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 L+TG GIG L + ++ V T DL + + CP +E + + Sbjct: 10 ALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAK--------ECPG--IEPVCV 59 Query: 66 DVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQA 125 D+ D + A + G VD+LV NA L ++ P + ++A VN+ ++ Q Sbjct: 60 DLGDWDATEKALGGI--GPVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNLRSVFQVSQM 117 Query: 126 FLPDMKRRGS-GRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLI 184 DM RG G ++ S+ + P Y ++K A+ L +++A+ L P + ++ + Sbjct: 118 VARDMINRGVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMELGPHKIRVNSV 177 Query: 185 ECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQ 218 V T +KV PE + H +F + Sbjct: 178 NPTVVLTDMGKKVSADPEFARKLKERHPLRKFAE 211 >3U5T-A nrPDB Length = 267 Score = 182 bits (463), Expect = 1e-46, Method: Composition-based stats. Identities = 68/266 (25%), Positives = 101/266 (37%), Gaps = 29/266 (10%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 V ++TG S GIG +A RLASD YA E A + G Sbjct: 26 TNKVAIVTGASRGIGAAIAARLASDGFTVVINYA-----GKAAAAEEVAGKIEAAGGKAL 80 Query: 62 TLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGT 119 T Q DV D +V E G VDVLV NAG+ L + G+ V+ VN+ GT Sbjct: 81 TAQADVSDPAAVRRLFATAEEAFGGVDVLVNNAGIMPLTTIAETGDAVFDRVIAVNLKGT 140 Query: 120 VRMLQAFLPDMKRRGSGRVLVTG-SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 L+ ++ GR++ S GL+ P +Y A+K +E + L+ L Sbjct: 141 FNTLREAAQRLRV--GGRIINMSTSQVGLL-HPSYGIYAAAKAGVEAMTHVLSKELRGRD 197 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 + ++ + GP T + G +EV DR +K E P+++A Sbjct: 198 ITVNAVAPGPTATDLFLE--GKSDEVRDR--------------FAKLAPLERLGTPQDIA 241 Query: 239 E--VFLTALRAPKPTLRYFTTERFLP 262 FL + + Sbjct: 242 GAVAFLAGPDGAWVNGQVLRANGGII 267 >4TRR-A nrPDB Length = 269 Score = 182 bits (462), Expect = 2e-46, Method: Composition-based stats. Identities = 57/265 (21%), Positives = 100/265 (37%), Gaps = 16/265 (6%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + ++TG +SGIG +A+ LA + A + G Sbjct: 12 LNGKTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANA------VADEINKAGGKA 65 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 + +DV + ++V ++V E G VD+LV NAG+ ++ P+E + ++V G Sbjct: 66 IGVAMDVTNEEAVNTGIDKVAEAFGSVDILVSNAGIQIVNPIENYSFADWKKMQAIHVDG 125 Query: 119 TVRMLQAFLPDMKRR-GSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 +A L M + G V+ GSV P Y +K L GL LA Sbjct: 126 AFLTTKAALKHMYKDDRGGVVIYMGSVHSHEASPLKSAYVTAKHGLLGLARVLAKEGAKH 185 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV 237 V ++ G V T ++K + + L ++ + ++V Sbjct: 186 NVRSHVVCPGFVRTPLVDKQIPEQAKELGISEEEVIKKVMLGNT-----VDGVFTTVQDV 240 Query: 238 AE--VFLTALRAPKPTLRYFTTERF 260 A+ +FL+A + T + F Sbjct: 241 AQTVLFLSAFPSAALTGQSFIVSHG 265 >3D3W-A nrPDB Length = 244 Score = 181 bits (460), Expect = 3e-46, Method: Composition-based stats. Identities = 53/219 (24%), Positives = 96/219 (43%), Gaps = 13/219 (5%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 +A VL+TG GIG L + ++ V T DL + R CP + Sbjct: 5 LAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVR--------ECPG--I 54 Query: 61 ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 E + +D+ D ++ A V G VD+LV NA + LL P + ++A +VN+ + Sbjct: 55 EPVCVDLGDWEATERALGSV--GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVI 112 Query: 121 RMLQAFLPDMKRRGS-GRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGV 179 ++ Q + RG G ++ S + + VYC++K AL+ L + +A+ L P + Sbjct: 113 QVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKI 172 Query: 180 HLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQ 218 ++ + V T+ + P + + +F + Sbjct: 173 RVNAVNPTVVMTSMGQATWSDPHKAKTMLNRIPLGKFAE 211 >4HP8-A nrPDB Length = 247 Score = 181 bits (460), Expect = 3e-46, Method: Composition-based stats. Identities = 58/265 (21%), Positives = 102/265 (38%), Gaps = 29/265 (10%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + L+TG ++G+G +AV LA+ ++ D E +A G+ Sbjct: 7 LEGRKALVTGANTGLGQAIAVGLAAAGAEVVCAARRAPD--------ETLDIIAKDGGNA 58 Query: 61 ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 L +D D AA++ T+ D+LV NAG+ E V+DVN+ Sbjct: 59 SALLIDFADPL---AAKDSFTDAGFDILVNNAGIIRRADSVEFSELDWDEVMDVNLKALF 115 Query: 121 RMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGV 179 QAF ++ +G SG+V+ S+ G Y A+K + GL + LA G+ Sbjct: 116 FTTQAFAKELLAKGRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTKLLANEWAAKGI 175 Query: 180 HLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV-- 237 +++ I G + T E + + A +++ + E++ Sbjct: 176 NVNAIAPGYIETNNTEALRAD---------------AARNKAILERIPAGRWGHSEDIAG 220 Query: 238 AEVFLTALRAPKPTLRYFTTERFLP 262 A VFL++ A + Sbjct: 221 AAVFLSSAAADYVHGAILNVDGGWL 245 >3RWB-A nrPDB Length = 247 Score = 181 bits (460), Expect = 4e-46, Method: Composition-based stats. Identities = 58/266 (21%), Positives = 100/266 (37%), Gaps = 30/266 (11%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 +A L+TG + GIG +A RLA+D + K A Sbjct: 4 LAGKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAA---------ASIGKKA 54 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 + D+ D SV A + G +D+LV NA + + + D ++DVN+ G Sbjct: 55 RAIAADISDPGSVKALFAEIQALTGGIDILVNNASIVPFVAWDDVDLDHWRKIIDVNLTG 114 Query: 119 TVRMLQAFLPDMKRRGS-GRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 T + +A M+ G GRV+ S G P Y A+K + G +LA L + Sbjct: 115 TFIVTRAGTDQMRAAGKAGRVISIASNTFFAGTPNMAAYVAAKGGVIGFTRALATELGKY 174 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV 237 + + + G + + ++ + + F + L + PE + Sbjct: 175 NITANAVTPGLIESDGVKA-----------SPHNEAFGFVEMLQ-----AMKGKGQPEHI 218 Query: 238 AEV--FLTALRAPKPTLRYFTTERFL 261 A+V FL + A T + + + Sbjct: 219 ADVVSFLASDDARWITGQTLNVDAGM 244 >3UF0-A nrPDB Length = 273 Score = 180 bits (458), Expect = 5e-46, Method: Composition-based stats. Identities = 65/265 (24%), Positives = 100/265 (37%), Gaps = 25/265 (9%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 +A ++TG SGIG +A A + T + E A +A GS Sbjct: 29 LAGRTAVVTGAGSGIGRAIAHGYARAGAHVLAWGRT-------DGVKEVADEIADGGGSA 81 Query: 61 ETLQLDVRDSK-SVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGT 119 E + D+ D + + A E RVDVLV NAG+ P E + VL VN+ Sbjct: 82 EAVVADLADLEGAANVAEELAATRRVDVLVNNAGIIARAPAEEVSLGRWREVLTVNLDAA 141 Query: 120 VRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGV 179 + ++F M GSGR++ S+ G Y ASK A+ GL +LA GV Sbjct: 142 WVLSRSFGTAMLAHGSGRIVTIASMLSFQGGRNVAAYAASKHAVVGLTRALASEWAGRGV 201 Query: 180 HLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA- 238 ++ + G V TA + E + + ++ PE++ Sbjct: 202 GVNALAPGYVVTANTAALRADDERAAE---------------ITARIPAGRWATPEDMVG 246 Query: 239 -EVFLTALRAPKPTLRYFTTERFLP 262 VFL + A + + Sbjct: 247 PAVFLASDAASYVHGQVLAVDGGWL 271 >3OIC-A nrPDB Length = 258 Score = 180 bits (456), Expect = 1e-45, Method: Composition-based stats. Identities = 57/264 (21%), Positives = 100/264 (37%), Gaps = 20/264 (7%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 62 L+TG S G+G A+RLA + YA +++ E A + + Sbjct: 4 NKCALVTGSSRGVGKAAAIRLAENGYNIVINYA-----RSKKAALETAEEIEKLGVKVLV 58 Query: 63 LQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 ++ +V + +++ E GR+DV V NA G+L P+ L E +++N + Sbjct: 59 VKANVGQPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELEETHWDWTMNINAKALL 118 Query: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180 Q M++ G G ++ S+G + L SK ALE L LAV L P + Sbjct: 119 FCAQEAAKLMEKNGGGHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAVELSPKQII 178 Query: 181 LSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV 240 ++ + G + T ++ + + D R + V Sbjct: 179 VNAVSGGAIDTDALKHFPNREDLLEDARQNTPAGRMVEIKDMVDTVE------------- 225 Query: 241 FLTALRAPKPTLRYFTTERFLPLL 264 FL + +A + + LL Sbjct: 226 FLVSSKADMIRGQTIIVDGGRSLL 249 >3OML-A nrPDB Length = 613 Score = 179 bits (454), Expect = 2e-45, Method: Composition-based stats. Identities = 73/306 (23%), Positives = 115/306 (37%), Gaps = 28/306 (9%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVY---ATLRDLKTQGRLWEAARALACPPGS 59 V ++TG +G+G A+ A ++ D +Q + G Sbjct: 19 GRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRKAGGE 78 Query: 60 LETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGT 119 V D V + GRVD+LV NAG+ L E V DV++ G+ Sbjct: 79 AVADYNSVIDGAKVIETAIKA-FGRVDILVNNAGILRDRSLVKTSEQDWNLVNDVHLKGS 137 Query: 120 VRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGV 179 + QA P MK++ GR+++T S G+ G Y A+K L GL ++A+ V Sbjct: 138 FKCTQAAFPYMKKQNYGRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLANTVAIEGARNNV 197 Query: 180 HLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE 239 ++I + E +L P+ + + YL H + E A Sbjct: 198 LCNVIVPTA-ASRMTEGIL--PDILFNELKPKLIAPVVAYLCHESCEDNGSYI---ESAA 251 Query: 240 VFLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFGDVPAKAEAG---- 295 + T L + LR LDDP YV ++V+ +V ++A Sbjct: 252 GWATKLHMVRGKGAV---------LRPSLDDPVTIEYV----KDVWSNVTDMSKAKHLGA 298 Query: 296 -AEAGG 300 AEA G Sbjct: 299 IAEASG 304 >6CI9-A nrPDB Length = 259 Score = 179 bits (454), Expect = 2e-45, Method: Composition-based stats. Identities = 62/266 (23%), Positives = 99/266 (37%), Gaps = 24/266 (9%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + ++TG S GIG +A A+ DL L+ G + Sbjct: 7 LEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLD------RTVADLSGTRGKV 60 Query: 61 ETLQLDVRDSKSVAAARERVT--EGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 ++ DV D + G +D++ NAG+ G LE L D + VL VN G Sbjct: 61 TAVRADVTDPEDARRTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKG 120 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGG-LMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 TV ++QA L + G GRV+VT S+ G + G P Y ASK A G + A+ L P Sbjct: 121 TVYIVQAALQALTASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAMELAPK 180 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV 237 + ++ + G + T ++++ + + R Sbjct: 181 KITINAVLPGNIMTEGLDEMGQDYLDQM--ASAIPAGRLGSVADIGN------------- 225 Query: 238 AEVFLTALRAPKPTLRYFTTERFLPL 263 A +F A T + + L Sbjct: 226 AALFFATDEAAYVTGQTLVVDGGQVL 251 >4FC7-A nrPDB Length = 277 Score = 177 bits (449), Expect = 6e-45, Method: Composition-based stats. Identities = 58/264 (21%), Positives = 99/264 (37%), Gaps = 23/264 (8%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + V ITG SGIG +A + +L + T R A C P Sbjct: 25 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLP--- 81 Query: 61 ETLQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 L +DVR +V AA ++ GR+D+L+ A L P AL +A +V+D++ G Sbjct: 82 --LSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG 139 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 T + + R G ++ + G G ++K A++ + LAV P Sbjct: 140 TFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN 199 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 + ++ + GP+ + LG P+ L + + N E+A Sbjct: 200 IRVNSLAPGPISGTEGLRRLGGPQASLSTKVTAS--------------PLQRLGNKTEIA 245 Query: 239 E--VFLTALRAPKPTLRYFTTERF 260 ++L + A T + Sbjct: 246 HSVLYLASPLASYVTGAVLVADGG 269 >5IZ4-A nrPDB Length = 271 Score = 177 bits (448), Expect = 7e-45, Method: Composition-based stats. Identities = 68/273 (24%), Positives = 104/273 (38%), Gaps = 28/273 (10%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 + V +ITG +SGIG A+R A V D T+ Sbjct: 13 STPVCVITGSASGIGAATALRFAQAGWS---VAIGNFDDSTRDAASTVEALCRDAGAQTL 69 Query: 62 TLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGP---LEALGEDAVASVLDVNV 116 DV A + V R+D L+ AG + P + + + V VN+ Sbjct: 70 IFDADVGKDADCRHAVDMVASRWQRIDALINCAGTTRVIPHNAFDQIDDFEFERVYRVNL 129 Query: 117 VGTVRMLQAFLPDMKRRGSG----RVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAV 172 +G +M +A +P ++ S V+ S+ GL G + Y ASK A+ L SLA Sbjct: 130 IGLYQMTRAAVPLLRESASATRSTSVVNVSSLAGLNGTGSSIAYAASKGAVNTLTLSLAR 189 Query: 173 LLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQ 232 L P + ++ + G V + +VL D + + S + + Sbjct: 190 NLAPH-IRVNALAPGMVDDGLLLRVL----------DAAAYDGVLSRMTESAPL--KRVS 236 Query: 233 NPEEVAEV--FLTALRAPKPTLRYFTTERFLPL 263 P E+AE+ FLTA AP T + E L L Sbjct: 237 RPAEIAELAWFLTA-HAPAITGQVIAAENGLLL 268 >4MOW-A nrPDB Length = 256 Score = 175 bits (445), Expect = 2e-44, Method: Composition-based stats. Identities = 60/265 (22%), Positives = 100/265 (37%), Gaps = 25/265 (9%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 +A V ++TG S GIG +A LA + + YA+ ++ A+ G Sbjct: 12 LAGKVAIVTGASKGIGAAIAKALADEGAAVVVNYAS-----SKAGADAVVSAITEAGGRA 66 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 + DV + + E GR+DVLV N+G+ P+EA+ E+ D NV G Sbjct: 67 VAVGGDVSKAADAQRIVDTAIETYGRLDVLVNNSGVYEFAPIEAITEEHYRRQFDTNVFG 126 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 + QA + + ++ SV + P + VY +K A++ + LA+ L P Sbjct: 127 VLLTTQAAVKHLGE--GASIINISSVVTSITPPASAVYSGTKGAVDAITGVLALELGPRK 184 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 + ++ I G + T + T Q P ++A Sbjct: 185 IRVNAINPGMIVT--------------EGTHSAGIIGSDLEAQVLGQTPLGRLGEPNDIA 230 Query: 239 E--VFLTALRAPKPTLRYFTTERFL 261 VFL + A T + L Sbjct: 231 SVAVFLASDDARWMTGEHLVVSGGL 255 >3RKU-A nrPDB Length = 287 Score = 175 bits (445), Expect = 2e-44, Method: Composition-based stats. Identities = 65/253 (25%), Positives = 102/253 (40%), Gaps = 5/253 (1%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 +A+ VLITG S+GIG A+ + K+ R L+ L + P + Sbjct: 31 LAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQ-EFPNAKV 89 Query: 61 ETLQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLG-PLEALGEDAVASVLDVNVV 117 QLD+ ++ + E + +D+LV NAG L + + + + V D NV Sbjct: 90 HVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQIATEDIQDVFDTNVT 149 Query: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 + + QA LP + + SG ++ GS+ G P +YCASKFA+ +SL L+ Sbjct: 150 ALINITQAVLPIFQAKNSGDIVNLGSIAGRDAYPTGSIYCASKFAVGAFTDSLRKELINT 209 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV 237 + + LI G V T F EE T +A QN + Sbjct: 210 KIRVILIAPGLVETEFSLVRYRGNEEQAKNVYKDTTPLMADDVADLIVYATSRKQN-TVI 268 Query: 238 AEVFLTALRAPKP 250 A+ + P Sbjct: 269 ADTLIFPTNQASP 281 >1K2W-A nrPDB Length = 256 Score = 175 bits (444), Expect = 2e-44, Method: Composition-based stats. Identities = 64/266 (24%), Positives = 104/266 (39%), Gaps = 22/266 (8%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPG-S 59 + LITG + GIG A + ++ L EAARA A G + Sbjct: 3 LDGKTALITGSARGIGRAFAEAYVREGARVAIADINL----------EAARATAAEIGPA 52 Query: 60 LETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVV 117 + LDV D S+ + + G +D+LV NA L L P+ + ++ + +NV Sbjct: 53 ACAIALDVTDQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVS 112 Query: 118 GTVRMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLP 176 GT+ M+QA M G G+++ S G G VYCA+K A+ L +S + L+ Sbjct: 113 GTLFMMQAVARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNLIR 172 Query: 177 FGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEE 236 G++++ I G V + V D R + V E+ Sbjct: 173 HGINVNAIAPGVVDGEHWDGVDAK------FADYENLPRGEKKRQVGAAVPFGRMGRAED 226 Query: 237 VAEV--FLTALRAPKPTLRYFTTERF 260 + + FL A + + + Sbjct: 227 LTGMAIFLATPEADYIVAQTYNVDGG 252 >3V8B-A nrPDB Length = 283 Score = 175 bits (443), Expect = 3e-44, Method: Composition-based stats. Identities = 67/268 (25%), Positives = 107/268 (39%), Gaps = 21/268 (7%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 V LITG SGIG A+ LA+D + T + + E A + G L+ Sbjct: 30 VALITGAGSGIGRATALALAADGVTVGALGRT------RTEVEEVADEIVGAGGQAIALE 83 Query: 65 LDVRDSKSVAAARE--RVTEGRVDVLVCNAGLG-LLGPLEALGEDAVASVLDVNVVGTVR 121 DV D + A + G +D++V NAG+ + P++ L + VN+ GT Sbjct: 84 ADVSDELQMRNAVRDLVLKFGHLDIVVANAGINGVWAPIDDLKPFEWDETIAVNLRGTFL 143 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGL--PFNDVYCASKFALEGLCESLAVLLLPFGV 179 L +P +K+RG G ++V S+ G P Y A+K A + + LA+ L + Sbjct: 144 TLHLTVPYLKQRGGGAIVVVSSINGTRTFTTPGATAYTATKAAQVAIVQQLALELGKHHI 203 Query: 180 HLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE 239 ++ + G + T + EE + + E+VAE Sbjct: 204 RVNAVCPGAIETNISDNTKLRHEEETAIPVEWPKGQV--------PITDGQPGRSEDVAE 255 Query: 240 V--FLTALRAPKPTLRYFTTERFLPLLR 265 + FL + RA T + LLR Sbjct: 256 LIRFLVSERARHVTGSPVWIDGGQGLLR 283 >2NWQ-A nrPDB Length = 272 Score = 173 bits (439), Expect = 1e-43, Method: Composition-based stats. Identities = 62/250 (24%), Positives = 99/250 (39%), Gaps = 28/250 (11%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETL 63 + + ITG +SG G A R A L+ A + L Sbjct: 22 STLFITGATSGFGEACARRFAEAGWSLVLTGRREERLQALAGELSAKT-------RVLPL 74 Query: 64 QLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLG-PLEALGEDAVASVLDVNVVGTV 120 LDVRD +++AA + + E + L+ NAGL L P ++ D +++D N+ G + Sbjct: 75 TLDVRDRAAMSAAVDNLPEEFATLRGLINNAGLALGTDPAQSCDLDDWDTMVDTNIKGLL 134 Query: 121 RMLQAFLPDMKRRGSG-RVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGV 179 + LP + G+G ++ GSV G P + VY +K +E +L L GV Sbjct: 135 YSTRLLLPRLIAHGAGASIVNLGSVAGKWPYPGSHVYGGTKAFVEQFSLNLRCDLQGTGV 194 Query: 180 HLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE 239 ++ +E G + F G + D+T AH Q PE++AE Sbjct: 195 RVTNLEPGLCESEFSLVRFGGDQARYDKTYAG---------AHPIQ--------PEDIAE 237 Query: 240 VFLTALRAPK 249 + P Sbjct: 238 TIFWIMNQPA 247 >4E6P-A nrPDB Length = 259 Score = 173 bits (438), Expect = 1e-43, Method: Composition-based stats. Identities = 51/227 (22%), Positives = 89/227 (39%), Gaps = 12/227 (5%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + LITG + GIG A + + + + A + Sbjct: 6 LEGKSALITGSARGIGRAFAEAYVREGATVAIADIDIERARQAA---------AEIGPAA 56 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 +Q+DV S+ AA E G +D+LV NA L L P+ + ++ + +NV G Sbjct: 57 YAVQMDVTRQDSIDAAIAATVEHAGGLDILVNNAALFDLAPIVEITRESYEKLFAINVAG 116 Query: 119 TVRMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 T+ LQA M +G G+++ S G G +YCA+K A+ L +S + L+ Sbjct: 117 TLFTLQAAARQMIAQGRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAGLDLIKH 176 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSK 224 ++++ I G V + V +R + + + Sbjct: 177 RINVNAIAPGVVDGEHWDGVDALFARYENRPRGEKKRLVGEAVPFGR 223 >5OJG-A nrPDB Length = 260 Score = 170 bits (431), Expect = 7e-43, Method: Composition-based stats. Identities = 42/263 (15%), Positives = 90/263 (34%), Gaps = 18/263 (6%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 V ++T + GIGL +A RL + + +++ + + Sbjct: 9 EGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIAGH 68 Query: 62 TLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGL-LGPLEALGEDAVASVLDVNVVGTV 120 D + G++++LV N G+ G + + + + +VNV Sbjct: 69 IAS---TDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVKAGF 125 Query: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180 +M + P + + G G ++ S P Y +K L GL +LA+ L + Sbjct: 126 QMTKLVHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIR 185 Query: 181 LSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE- 239 ++ I G + T + + E+ + L +++ P++ A Sbjct: 186 VNGIAPGVIKTKMSQVLWDGGEDA------------EKELTDIQEIALGRLGVPDDCAGT 233 Query: 240 -VFLTALRAPKPTLRYFTTERFL 261 +L + + T + Sbjct: 234 VAYLASDDSSYITGEMIIIAGGV 256 >1O5I-A nrPDB Length = 249 Score = 170 bits (431), Expect = 8e-43, Method: Composition-based stats. Identities = 55/258 (21%), Positives = 105/258 (40%), Gaps = 37/258 (14%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 VL+ S GIG +A L+ + ++ LK G + Sbjct: 22 VLVLAASRGIGRAVADVLSQEGAEVTICARNEELLKRSG---------------HRYVVC 66 Query: 66 DVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQA 125 D+R K + E+V E VD+LV NAG G + L + +D + +++++ Sbjct: 67 DLR--KDLDLLFEKVKE--VDILVLNAGGPKAGFFDELTNEDFKEAIDSLFLNMIKIVRN 122 Query: 126 FLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIE 185 +LP MK +G GR++ S + + +++ AL G ++L+ + P+G+ ++ + Sbjct: 123 YLPAMKEKGWGRIVAITSFSVISPIENLYTSNSARMALTGFLKTLSFEVAPYGITVNCVA 182 Query: 186 CGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV--FLT 243 G T ++++L ++ Q+ PEE+A V FL Sbjct: 183 PGWTETERVKELLSEEKK----------------KQVESQIPMRRMAKPEEIASVVAFLC 226 Query: 244 ALRAPKPTLRYFTTERFL 261 + +A T + + L Sbjct: 227 SEKASYLTGQTIVVDGGL 244 >2FWM-X nrPDB Length = 250 Score = 167 bits (423), Expect = 6e-42, Method: Composition-based stats. Identities = 56/266 (21%), Positives = 93/266 (34%), Gaps = 27/266 (10%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 + V +TG GIG A+ ++ +A Sbjct: 6 SGKNVWVTGAGKGIGYATALAFVEAGAKVTGFD----------------QAFTQEQYPFA 49 Query: 62 TLQLDVRDSKSVAAARER--VTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGT 119 T +DV D+ VA +R R+D LV AG+ +G + L ++ VNV G Sbjct: 50 TEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGA 109 Query: 120 VRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGV 179 + Q + +R+ G ++ S Y ASK AL+ L S+ + L GV Sbjct: 110 FNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGV 169 Query: 180 HLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE 239 +++ G T + V D + F + + P+E+A Sbjct: 170 RCNVVSPGSTDTDMQRTLW-----VSDDAEEQRIRGFGEQFKLG--IPLGKIARPQEIAN 222 Query: 240 --VFLTALRAPKPTLRYFTTERFLPL 263 +FL + A TL+ + L Sbjct: 223 TILFLASDLASHITLQDIVVDGGSTL 248 >4RGB-A nrPDB Length = 294 Score = 167 bits (423), Expect = 6e-42, Method: Composition-based stats. Identities = 64/280 (22%), Positives = 106/280 (37%), Gaps = 23/280 (8%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLR------DLKTQGRLWEAARALA 54 + VV ITG + G G AV A + V L T L E AR + Sbjct: 23 LDGRVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEETARLVE 82 Query: 55 CPPGSLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVL 112 + + DVRD + + E G +D ++ NAG+ L P E +A+ L Sbjct: 83 KTGQEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLTNPDERDASEALRLGL 142 Query: 113 DVNVVGTVRMLQAFLPDMKRRG-SGRVLVTGSVGGLM----GLPFNDVYCASKFALEGLC 167 D+ ++G Q +P MK RG G ++ T S+ L+ G D Y SK A+ GL Sbjct: 143 DIMLIGVWNTFQVAIPHMKERGQGGNLIATSSMIALLDLTDGRGGTDAYLTSKLAITGLV 202 Query: 168 ESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVF 227 S A++L + ++ + T + + + + + + A S + Sbjct: 203 RSYALMLAADRIRVNGVAPTNCSTPMITENPALFKVIEENPHLVN--------AMSTALP 254 Query: 228 REAAQNPEEVAEV--FLTALRAPKPTLRYFTTERFLPLLR 265 P +V+ FL + T + + + R Sbjct: 255 DFPMIEPRDVSNAILFLISDAGRSFTGSVLKVDAGMDVKR 294 >2B4Q-A nrPDB Length = 276 Score = 167 bits (422), Expect = 7e-42, Method: Composition-based stats. Identities = 59/272 (21%), Positives = 95/272 (34%), Gaps = 31/272 (11%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 +A + L+TG S GIG +A L ++ F A G Sbjct: 27 LAGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSA-------YGDC 79 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 + + D+ + + E R+D+LV NAG LE+ V+ +NV Sbjct: 80 QAIPADLSSEAGARRLAQALGELSARLDILVNNAGTSWGAALESYPVSGWEKVMQLNVTS 139 Query: 119 TVRMLQAFLPDMKRRGS----GRVLVTGSVGGLMGLPFND-VYCASKFALEGLCESLAVL 173 +Q LP ++R S RV+ GSV G+ + Y SK AL L LA Sbjct: 140 VFSCIQQLLPLLRRSASAENPARVINIGSVAGISAMGEQAYAYGPSKAALHQLSRMLAKE 199 Query: 174 LLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQN 233 L+ +++++I G + + P+ + A S + Sbjct: 200 LVGEHINVNVIAPGRFPSRMTRHIANDPQAL---------------EADSASIPMGRWGR 244 Query: 234 PEEVAEVF--LTALRAPKPTLRYFTTERFLPL 263 PEE+A + L T + L Sbjct: 245 PEEMAALAISLAGTAGAYMTGNVIPIDGGFHL 276 >2AG5-A nrPDB Length = 246 Score = 166 bits (421), Expect = 1e-41, Method: Composition-based stats. Identities = 56/249 (22%), Positives = 96/249 (38%), Gaps = 33/249 (13%) Query: 21 VRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAARERV 80 + A + ++ L + L PG ++T LDV K + V Sbjct: 24 LAFAREGAKVIATDINESKL----------QELEKYPG-IQTRVLDVTKKKQIDQFANEV 72 Query: 81 TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLV 140 R+DVL AG G + E +++NV M++AFLP M + SG ++ Sbjct: 73 E--RLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIIN 130 Query: 141 TGSVG-GLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVL- 198 SV + G+ VY +K A+ GL +S+A + G+ + + G V T +++ + Sbjct: 131 MSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQ 190 Query: 199 --GSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE--VFLTALRAPKPTLRY 254 G+PEE + K+ EE+A V+L + + T Sbjct: 191 ARGNPEEARN--------------DFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNP 236 Query: 255 FTTERFLPL 263 + L Sbjct: 237 VIIDGGWSL 245 >3ZV3-A nrPDB Length = 281 Score = 164 bits (414), Expect = 7e-41, Method: Composition-based stats. Identities = 52/234 (22%), Positives = 91/234 (38%), Gaps = 19/234 (8%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + V LITG +SG+G L R ++ ++ + + L+ G+ Sbjct: 3 LTGEVALITGGASGLGRALVDRFVAEGARVAVLDKSAERLRELE---------VAHGGNA 53 Query: 61 ETLQLDVRDSKSVAAARER--VTEGRVDVLVCNAGLGLLGPLEALGEDA-----VASVLD 113 + DVR + A ER G++D L+ NAG+ A + + Sbjct: 54 VGVVGDVRSLQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDIFH 113 Query: 114 VNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVL 173 VNV G + ++A LP + G V+ T S G +Y A+K A+ GL +A Sbjct: 114 VNVKGYIHAVKACLPALVSSR-GSVVFTISNAGFYPNGGGPLYTATKHAVVGLVRQMAFE 172 Query: 174 LLPFGVHLSLIECGPVHTAF-MEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQV 226 L P V ++ + G ++T LG E+ + + + + + Sbjct: 173 LAPH-VRVNGVAPGGMNTDLRGPSSLGLSEQSISSVPLADMLKSVLPIGRMPAL 225 >2O23-A nrPDB Length = 265 Score = 163 bits (413), Expect = 8e-41, Method: Composition-based stats. Identities = 63/269 (23%), Positives = 98/269 (36%), Gaps = 39/269 (14%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + V +ITG +SG+GL A RL + + + DL G +A + + Sbjct: 10 VKGLVAVITGGASGLGLATAERLVGQGASAVLL-----DLPNSGGEAQAKK----LGNNC 60 Query: 61 ETLQLDVRDSKSVAAARERVT--EGRVDVLVCNAGLGLLGPLEAL------GEDAVASVL 112 DV K V A GRVDV V AG+ + L + VL Sbjct: 61 VFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVL 120 Query: 113 DVNVVGTVRMLQAFLPDMKRR------GSGRVLVTGSVGGLMGLPFNDVYCASKFALEGL 166 DVN++GT +++ +M + G ++ T SV G Y ASK + G+ Sbjct: 121 DVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 180 Query: 167 CESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQV 226 +A L P G+ + I G T + + PE+V + S+ Sbjct: 181 TLPIARDLAPIGIRVMTIAPGLFGTPLLTSL---PEKVCN-------------FLASQVP 224 Query: 227 FREAAQNPEEVAEVFLTALRAPKPTLRYF 255 F +P E A + + P Sbjct: 225 FPSRLGDPAEYAHLVQAIIENPFLNGEVI 253 >5T5Q-A nrPDB Length = 247 Score = 163 bits (413), Expect = 9e-41, Method: Composition-based stats. Identities = 47/266 (17%), Positives = 90/266 (33%), Gaps = 31/266 (11%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 +++TG + GIG +A + + L P + Sbjct: 8 ENRTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASL-------GSPERIA 60 Query: 62 TLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGT 119 T++ D + E G +D LV +AG+ P + + + +N+ G Sbjct: 61 TIKADASSADDAEKTVALAMERFGGIDFLVPSAGIYQAKPFAEMSDADWHRTISINLDGV 120 Query: 120 VRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGV 179 + + LP +K ++ S+ G N Y A+K A+ + +L+ L P Sbjct: 121 FYLCKRALPALKEDS--SIVTLASLAAYRGAYVNAHYGATKGAMVSMTRALSRELAPKT- 177 Query: 180 HLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE 239 ++ + G + T ++L + +D T Q + P E+A Sbjct: 178 RVNGVSPGIIETPMTSELLKT---RMDET--------------MTQTPLKRLGKPSEIAS 220 Query: 240 V--FLTALRAPKPTLRYFTTERFLPL 263 V FL + A T + + Sbjct: 221 VIAFLCSPAASFVTGETIQVNGGIYM 246 >1E3W-A nrPDB Length = 261 Score = 160 bits (406), Expect = 5e-40, Method: Composition-based stats. Identities = 57/269 (21%), Positives = 97/269 (36%), Gaps = 39/269 (14%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + V +ITG +SG+GL A RL + + + + +T+ + G+ Sbjct: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAK---------KLGGNC 58 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEAL------GEDAVASVL 112 +V K V AA E GR+DV V AG+ + + V+ Sbjct: 59 IFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVI 118 Query: 113 DVNVVGTVRMLQAFLPDMKRR------GSGRVLVTGSVGGLMGLPFNDVYCASKFALEGL 166 +VN++GT +++ M + G ++ T SV G Y ASK + G+ Sbjct: 119 NVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 Query: 167 CESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQV 226 +A L P G+ + I G T + + P+ V + S+ Sbjct: 179 TLPIARDLAPIGIRVVTIAPGLFATPLLTTL---PDTVRN-------------FLASQVP 222 Query: 227 FREAAQNPEEVAEVFLTALRAPKPTLRYF 255 F +P E A + + P Sbjct: 223 FPSRLGDPAEYAHLVQMVIENPFLNGEVI 251 >1H5Q-A nrPDB Length = 265 Score = 160 bits (404), Expect = 9e-40, Method: Composition-based stats. Identities = 51/262 (19%), Positives = 95/262 (36%), Gaps = 34/262 (12%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 62 +++TG + GIGL +A+ + +Y + D + + + Sbjct: 14 NKTIIVTGGNRGIGLAFTRAVAAAGANVAVIYRSAADA-----VEVTEKVGKEFGVKTKA 68 Query: 63 LQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 Q DV ++ V +++ G + L+ NAG+ ++ P L + A V DVNV G Sbjct: 69 YQCDVSNTDIVTKTIQQIDADLGPISGLIANAGVSVVKPATELTHEDFAFVYDVNVFGVF 128 Query: 121 RMLQAFLPD-MKRRGSGRVLVTGSV-------GGLMGLPFNDVYCASKFALEGLCESLAV 172 +A ++++ G ++VT S+ L G Y +SK A L + LA Sbjct: 129 NTCRAVAKLWLQKQQKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSSKAACSNLVKGLAA 188 Query: 173 LLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQ 232 G+ ++ + G V+T + + + Sbjct: 189 EWASAGIRVNALSPGYVNTDQTAHMDKK-----------------IRDHQASNIPLNRFA 231 Query: 233 NPEEVA--EVFLTALRAPKPTL 252 PEE+ + L + A T Sbjct: 232 QPEEMTGQAILLLSDHATYMTG 253 >2HSD-A nrPDB Length = 253 Score = 159 bits (401), Expect = 2e-39, Method: Composition-based stats. Identities = 55/264 (20%), Positives = 91/264 (34%), Gaps = 30/264 (11%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 ++ V+ITG + G+G A + + ++ E A + Sbjct: 3 LSGKTVIITGGARGLGAEAARQAVAAGARVVLADVL---------DEEGAATARELGDAA 53 Query: 61 ETLQLDVRDSKSVAA--ARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 LDV + A R G VD LV NAG+ LE + V+++N+ G Sbjct: 54 RYQHLDVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVEINLTG 113 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 ++ +P MK G G ++ S GLMGL Y ASK+ + GL + AV L Sbjct: 114 VFIGMKTVIPAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDR 173 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 + ++ + G +T + Q + P E+A Sbjct: 174 IRVNSVHPGMTYTPMTAET-----------------GIRQGEGNYPNTPMGRVGEPGEIA 216 Query: 239 EVF--LTALRAPKPTLRYFTTERF 260 L + + T + Sbjct: 217 GAVVKLLSDTSSYVTGAELAVDGG 240 >4AVY-A nrPDB Length = 242 Score = 158 bits (400), Expect = 3e-39, Method: Composition-based stats. Identities = 55/261 (21%), Positives = 90/261 (34%), Gaps = 30/261 (11%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 A VL+TG SSGIG +A++ A ++ + + + Sbjct: 10 AGQQVLVTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHAPR------------HPRIR 57 Query: 62 TLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 +LD+ DS+ + E + R+DVLV NAG+ E VL +N+ + Sbjct: 58 REELDITDSQRLQRLFEALP--RLDVLVNNAGISRDR--EEYDLATFERVLRLNLSAAML 113 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 Q P + + G +L S+ G Y ASK A+ L SLA + + Sbjct: 114 ASQLARP-LLAQRGGSILNIASMYSTFGSADRPAYSASKGAIVQLTRSLACEYAAERIRV 172 Query: 182 SLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVF 241 + I G + T + + D+ R Q ++ + A F Sbjct: 173 NAIAPGWIDTPLGAGL---------KADVEATRRIMQRTPLARWGEAPEVAS----AAAF 219 Query: 242 LTALRAPKPTLRYFTTERFLP 262 L A T + Sbjct: 220 LCGPGASFVTGAVLAVDGGYL 240 >1DOH-A nrPDB Length = 283 Score = 157 bits (398), Expect = 5e-39, Method: Composition-based stats. Identities = 47/265 (17%), Positives = 100/265 (37%), Gaps = 16/265 (6%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + V L+TG GIG +A+ L + YA + E A+ Sbjct: 27 LEGKVALVTGAGRGIGREMAMELGRRGCKVIVNYAN-----STESAEEVVAAIKKNGSDA 81 Query: 61 ETLQLDVRDSKSVAAARERVT--EGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 ++ +V + + E G++D++ N+G+ G ++ + + V +N G Sbjct: 82 ACVKANVGVVEDIVRMFEEAVKIFGKLDIVCSNSGVVSFGHVKDVTPEEFDRVFTINTRG 141 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGL-MGLPFNDVYCASKFALEGLCESLAVLLLPF 177 + + ++ GR+++ GS+ G +P + VY SK A+E +A+ + Sbjct: 142 QFFVAREAYKHLEI--GGRLILMGSITGQAKAVPKHAVYSGSKGAIETFARCMAIDMADK 199 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV 237 + ++++ G + T V E + + ++ A + P ++ Sbjct: 200 KITVNVVAPGGIKTDMYHAVC--REYIPNGENLSN--EEVDEYAAVQWSPLRRVGLPIDI 255 Query: 238 AEV--FLTALRAPKPTLRYFTTERF 260 A V FL + T + + Sbjct: 256 ARVVCFLASNDGGWVTGKVIGIDGG 280 >1AHH-A nrPDB Length = 255 Score = 153 bits (387), Expect = 9e-38, Method: Composition-based stats. Identities = 49/264 (18%), Positives = 92/264 (34%), Gaps = 27/264 (10%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + +ITG +GIG +A+ A+ + + G Sbjct: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAAN------HVVDEIQQLGGQA 62 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 + D+ + ++A + G+VD+LV NAG G P + ++NV Sbjct: 63 FACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFS 121 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 + Q P+M++ G G +L S+ Y +SK A L ++A L Sbjct: 122 FFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKN 181 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 + ++ I G + T ++ V+ +PE + P+++A Sbjct: 182 IRVNGIAPGAILTDALKSVI-TPE---------------IEQKMLQHTPIRRLGQPQDIA 225 Query: 239 EV--FLTALRAPKPTLRYFTTERF 260 FL + A + + T Sbjct: 226 NAALFLCSPAASWVSGQILTVSGG 249 >3UN1-A nrPDB Length = 260 Score = 152 bits (385), Expect = 2e-37, Method: Composition-based stats. Identities = 54/262 (20%), Positives = 90/262 (34%), Gaps = 39/262 (14%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 62 + VV+ITG S GIG L ++++V AT R +K + T Sbjct: 28 QKVVVITGASQGIGAGLVRAY---RDRNYRVVATSRSIKPSADP------------DIHT 72 Query: 63 LQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 + D+ ++ E GR+D LV NAG+ L P + ++ L VNV G Sbjct: 73 VAGDISKPETADRIVREGIERFGRIDSLVNNAGVFLAKPFVEMTQEDYDHNLGVNVAGFF 132 Query: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCAS--KFALEGLCESLAVLLLPFG 178 + Q +M ++GSG ++ + + AS K L + SLA+ G Sbjct: 133 HITQRAAAEMLKQGSGHIVSITTSLVDQPMVGMPSALASLTKGGLNAVTRSLAMEFSRSG 192 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 V ++ + G + T H + + +V Sbjct: 193 VRVNAVSPGVIKTPM--------------------HPAETHSTLAGLHPVGRMGEIRDVV 232 Query: 239 EVFLTALRAPKPTLRYFTTERF 260 + L A T + Sbjct: 233 DAVLYLEHAGFITGEILHVDGG 254 >5O3Z-A nrPDB Length = 263 Score = 152 bits (384), Expect = 2e-37, Method: Composition-based stats. Identities = 59/263 (22%), Positives = 95/263 (36%), Gaps = 16/263 (6%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETL 63 V ++ G +G L LA + + G Sbjct: 7 QVAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTINS----RYGAGRAYGF 62 Query: 64 QLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 ++D D SV A V E GR D+LV +AG+ P+ L VN+VG Sbjct: 63 KVDATDEASVEALARAVDETFGRADLLVYSAGVAKAAPITQFRLTDFDLSLQVNLVGYFL 122 Query: 122 MLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180 + F M R G GR++ S G +G N Y A+KF GL +SLA+ L +G+ Sbjct: 123 CSREFSKLMIRDGIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDLAEYGIT 182 Query: 181 LSLIECG-PVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE 239 + + G + + + +L E L T + +V + + ++V Sbjct: 183 VHSLMLGNLLKSPMFQSLLPQYAEKLGITPEE------VEPYYVDKVPLKRGCDYQDVLN 236 Query: 240 VFL--TALRAPKPTLRYFTTERF 260 V L + +A T + Sbjct: 237 VLLFYASDKAAYCTGQSINVTGG 259 >3R3S-A nrPDB Length = 294 Score = 152 bits (384), Expect = 2e-37, Method: Composition-based stats. Identities = 51/261 (19%), Positives = 90/261 (34%), Gaps = 27/261 (10%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + L+TG SGIG A+ A + + Y + + + Sbjct: 47 LKDRKALVTGGDSGIGRAAAIAYAREGADVAINYLPAEE----EDAQQVKALIEECGRKA 102 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGP-LEALGEDAVASVLDVNVV 117 L D+ D + + E G +D+L AG P ++ L + VNV Sbjct: 103 VLLPGDLSDESFARSLVHKAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQTFAVNVF 162 Query: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 + Q +P + + ++ T S+ P Y A+K A+ LA + Sbjct: 163 ALFWITQEAIPLLPK--GASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEK 220 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV 237 G+ ++++ GP+ TA ++ +F Q Q + A P E+ Sbjct: 221 GIRVNIVAPGPIWTAL---------QISGGQTQDKIPQFGQ------QTPMKRAGQPAEL 265 Query: 238 AEVFLTALRAPKPTLRYFTTE 258 A V++ Y T E Sbjct: 266 APVYVYLASQES---SYVTAE 283 >1BDB-A nrPDB Length = 277 Score = 148 bits (375), Expect = 2e-36, Method: Composition-based stats. Identities = 49/200 (24%), Positives = 84/200 (42%), Gaps = 18/200 (9%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + VLITG +SG+G L R ++ ++ + + L ++ Sbjct: 3 LKGEAVLITGGASGLGRALVDRFVAEGAKVAVLDKSAERLAELET---------DHGDNV 53 Query: 61 ETLQLDVRDSKSVAAARER--VTEGRVDVLVCNAGLGLLGP-LEALGEDA----VASVLD 113 + DVR + A R G++D L+ NAG+ L L E++ V Sbjct: 54 LGIVGDVRSLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFH 113 Query: 114 VNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVL 173 +NV G + ++A LP + G V+ T S G +Y A+K A+ GL LA Sbjct: 114 INVKGYIHAVKACLPALVASR-GNVIFTISNAGFYPNGGGPLYTAAKHAIVGLVRELAFE 172 Query: 174 LLPFGVHLSLIECGPVHTAF 193 L P+ V ++ + G +++ Sbjct: 173 LAPY-VRVNGVGSGGINSDL 191 >3PXX-A nrPDB Length = 287 Score = 148 bits (373), Expect = 4e-36, Method: Composition-based stats. Identities = 70/282 (24%), Positives = 108/282 (38%), Gaps = 29/282 (10%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQS------FKVYATLRDLKTQGRLWEAARALACPP 57 VVL+TG + G G AV+LA + + + L T L EA + Sbjct: 11 KVVLVTGGARGQGRSHAVKLAEEGADIILFDICHDIETNEYPLATSRDLEEAGLEVEKTG 70 Query: 58 GSLETLQLDVRDSKSVAA--ARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVN 115 T ++DVRD +V+ A G++DV+V NAG+ LG L A A DV+ Sbjct: 71 RKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANAGICPLGA--HLPVQAFADAFDVD 128 Query: 116 VVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLM-----------GLPFNDVYCASKFALE 164 VG + + A LP + ++ TGSV GL+ P Y +K ++ Sbjct: 129 FVGVINTVHAALPYLTS--GASIITTGSVAGLIAAAQPPGAGGPQGPGGAGYSYAKQLVD 186 Query: 165 GLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSK 224 LA L P + ++I V+T + +P R D+ R LA Sbjct: 187 SYTLQLAAQLAPQSIRANVIHPTNVNTDMLN---SAPMYRQFRPDLEAPSRADALLAFPA 243 Query: 225 -QVFREAAQNPEEVAEV--FLTALRAPKPTLRYFTTERFLPL 263 Q +++ FL + + T F + L Sbjct: 244 MQAMPTPYVEASDISNAVCFLASDESRYVTGLQFKVDAGAML 285 >3E9N-A nrPDB Length = 245 Score = 147 bits (372), Expect = 6e-36, Method: Composition-based stats. Identities = 56/246 (22%), Positives = 104/246 (42%), Gaps = 20/246 (8%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + + + ++TG + G+G+ + L+ D VYA R+ + L E + Sbjct: 3 LKKKIAVVTGATGGMGIEIVKDLSRD----HIVYALGRNPEHLAALAEIE--------GV 50 Query: 61 ETLQLDVRDSKSVAAARERVTE-GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGT 119 E ++ D+ +++ VD LV A + +EA + LD+NV+ Sbjct: 51 EPIESDIVKEVLEEGGVDKLKNLDHVDTLVHAAAVARDTTIEAGSVAEWHAHLDLNVIVP 110 Query: 120 VRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGV 179 + + LP ++ SG V+ S G P N +Y ASK AL GL ++ G+ Sbjct: 111 AELSRQLLPALRAA-SGCVIYINSGAGNGPHPGNTIYAASKHALRGLADAFRKEEANNGI 169 Query: 180 HLSLIECGPVHTAFMEKVLGS------PEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQN 233 +S + GP +T ++ ++ S PE ++ +I RF + Q+ + Sbjct: 170 RVSTVSPGPTNTPMLQGLMDSQGTNFRPEIYIEPKEIANAIRFVIDAGETTQITNVDVRP 229 Query: 234 PEEVAE 239 E+A+ Sbjct: 230 RIELAD 235 >1HXH-A nrPDB Length = 253 Score = 147 bits (370), Expect = 8e-36, Method: Composition-based stats. Identities = 54/268 (20%), Positives = 97/268 (36%), Gaps = 28/268 (10%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + V L+TG +SG+GL + L + ++ + A Sbjct: 4 LQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLA---------AELGERS 54 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 ++ DV V G ++VLV NAG+ L G +E + + +L +N Sbjct: 55 MFVRHDVSSEADWTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRLEDFSRLLKINTES 114 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 Q + MK G G ++ SV + + Y ASK A+ L + A+ G Sbjct: 115 VFIGCQQGIAAMKETG-GSIINMASVSSWLPIEQYAGYSASKAAVSALTRAAALSCRKQG 173 Query: 179 --VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEE 236 + ++ I ++T M+ L P+ V +H K A PE Sbjct: 174 YAIRVNSIHPDGIYTPMMQASL--PKGVSKEMVLH----------DPKLNRAGRAYMPER 221 Query: 237 VAE--VFLTALRAPKPTLRYFTTERFLP 262 +A+ +FL + + + + + Sbjct: 222 IAQLVLFLASDESSVMSGSELHADNSIL 249 >3DWF-A nrPDB Length = 276 Score = 142 bits (358), Expect = 2e-34, Method: Composition-based stats. Identities = 54/199 (27%), Positives = 80/199 (40%), Gaps = 16/199 (8%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + V++TG S GIG +A LA + + L+ AR L S Sbjct: 9 LQGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKV-----VARCLELGAASA 63 Query: 61 ETLQLDVRDSKSVAAARERVTE-----GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVN 115 + + D + A E V E G +D+L+ N L D V ++VN Sbjct: 64 HYIAGSMED---MTFAEEFVAEAGNLMGGLDMLILNHVLYNRLTFFHGEIDNVRKSMEVN 120 Query: 116 VVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLL 175 V + A +P M + G + V SV G + P Y ASKFAL+G +L L Sbjct: 121 FHSFVVLSVAAMP-MLMQSQGSIAVVSSVAGKITYPLIAPYSASKFALDGFFSTLRSEFL 179 Query: 176 PFGVHLSLIEC--GPVHTA 192 V++S+ C G + T Sbjct: 180 VNKVNVSITLCILGLIDTE 198 >3GDF-A nrPDB Length = 267 Score = 142 bits (357), Expect = 3e-34, Method: Composition-based stats. Identities = 43/211 (20%), Positives = 79/211 (37%), Gaps = 11/211 (5%) Query: 1 MARTVVLITGCS--SGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPG 58 + VV++TG S G+G+ A A + YA+ + QG Sbjct: 18 LKGKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYAS----RAQGAEENVKELEKTYGI 73 Query: 59 SLETLQLDVRDSKSVAAARERVT--EGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNV 116 + + V +S + V G++D + NAG + +A V+ V++ Sbjct: 74 KAKAYKCQVDSYESCEKLVKDVVADFGQIDAFIANAGATADSGILDGSVEAWNHVVQVDL 133 Query: 117 VGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLP--FNDVYCASKFALEGLCESLAVLL 174 GT +A K RG+G +++T S+ G + Y +K + SLA Sbjct: 134 NGTFHCAKAVGHHFKERGTGSLVITASMSGHIANFPQEQTSYNVAKAGCIHMARSLANEW 193 Query: 175 LPFGVHLSLIECGPVHTAFMEKVLGSPEEVL 205 ++ I G + T + V +++ Sbjct: 194 -RDFARVNSISPGYIDTGLSDFVPKETQQLW 223 >5PGZ-A nrPDB Length = 276 Score = 141 bits (355), Expect = 5e-34, Method: Composition-based stats. Identities = 49/196 (25%), Positives = 81/196 (41%), Gaps = 10/196 (5%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + V++TG S GIG +A L+ + + L+ +R L S Sbjct: 16 LQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKV-----VSRCLELGAASA 70 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 + + D + + G +D+L+ N L +V V++VN + Sbjct: 71 HYIAGTMEDMTFAEQFIVKAGKLMGGLDMLILNHITQTSLSLFHDDIHSVRRVMEVNFLS 130 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 V M A LP M ++ +G + V S+ G M P Y ASKFAL+G ++ L Sbjct: 131 YVVMSTAALP-MLKQSNGSIAVISSLAGKMTQPMIAPYSASKFALDGFFSTIRTELYITK 189 Query: 179 VHLSLIEC--GPVHTA 192 V++S+ C G + T Sbjct: 190 VNVSITLCVLGLIDTE 205 >5JS6-A nrPDB Length = 274 Score = 140 bits (354), Expect = 7e-34, Method: Composition-based stats. Identities = 45/231 (19%), Positives = 79/231 (34%), Gaps = 27/231 (11%) Query: 20 AVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAARER 79 + ++ RAL + DV V Sbjct: 28 VRAFVNSGARVVICDKD----------ESGGRALEQELPGAVFILCDVTQEDDVKTLVSE 77 Query: 80 VT--EGRVDVLVCNAGL-GLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSG 136 GR+D +V NAG E +L++N++GT + + LP +++ G Sbjct: 78 TIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQ-G 136 Query: 137 RVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEK 196 V+ S+ G +G Y A+K A+ + ++LA+ P+GV ++ I G + T E+ Sbjct: 137 NVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEE 196 Query: 197 VLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV--AEVFLTAL 245 + + + P EV A VFL + Sbjct: 197 LAALMPDPRATIREGMLAQ-----------PLGRMGQPAEVGAAAVFLASE 236 >2HRB-A nrPDB Length = 274 Score = 138 bits (348), Expect = 3e-33, Method: Composition-based stats. Identities = 57/237 (24%), Positives = 76/237 (32%), Gaps = 54/237 (22%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETL 63 V L+TG + GIGL +A L S V T RD+ R A + L S Sbjct: 3 RVALVTGANRGIGLAIARELCRQFSG--DVVLTARDV---ARGQAAVQQLQAEGLSPRFH 57 Query: 64 QLDVRDSKSVAAARE--RVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 QLD+ D +S+ A R+ R G ++VLV NA + + L N T Sbjct: 58 QLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRN 117 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFN---------------------------- 153 M LP MK GRV+ S+ L Sbjct: 118 MCNELLPIMK--PHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVED 175 Query: 154 -------------DVYCASKFALEGLCESLAVLLLPF----GVHLSLIECGPVHTAF 193 Y SK + L LA L + ++ GPV T Sbjct: 176 TKNEVHEREGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDM 232 >4CR6-A nrPDB Length = 271 Score = 137 bits (346), Expect = 5e-33, Method: Composition-based stats. Identities = 67/275 (24%), Positives = 96/275 (34%), Gaps = 43/275 (15%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 +A ++TG + GIG + + + R AA P Sbjct: 13 LAGKAAIVTGAAGGIGRATVEAYLREGASVVAMDLAPR---------LAATRYEEPGAIP 63 Query: 61 ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGL---LGPLEALGEDAVASVLDVNVV 117 L R + A A G +D+LV AG L G L + +DVN+ Sbjct: 64 IACDLADRAAIDAAMADAVARLGGLDILV--AGGALKGGTGNFLDLSDADWDRYVDVNMT 121 Query: 118 GTVRMLQAFLPDMKRRGSG------RVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLA 171 GT +A M G+G R++ GSV M P Y A+K + L ++A Sbjct: 122 GTFLTCRAGARAMVAAGAGKDGRSARIITIGSVNSFMAEPEAAAYVAAKGGVAMLTRAMA 181 Query: 172 VLLLPFGVHLSLIECGPVHTAFMEKVLGSP---EEVLDRTDIHTFHRFYQYLAHSKQVFR 228 V L G+ +++I GPV P E+VLD +V Sbjct: 182 VDLARHGILVNMIAPGPVDVTGNNTGYSEPRLAEQVLD------------------EVAL 223 Query: 229 EAAQNPEEVAE--VFLTALRAPKPTLRYFTTERFL 261 PEEVA VFL + T T + L Sbjct: 224 GRPGLPEEVATAAVFLAEDGSSFITGSTITIDGGL 258 >5ILO-A nrPDB Length = 271 Score = 137 bits (344), Expect = 8e-33, Method: Composition-based stats. Identities = 47/198 (23%), Positives = 81/198 (40%), Gaps = 20/198 (10%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 62 ++TG + GIGL ++ +L + + + +L+ +L A P S+ Sbjct: 15 GKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRA-----AHPTQSVMI 69 Query: 63 LQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 +++DV + K V A E + T G +D++V AG+ + V L VN+ G + Sbjct: 70 IKMDVANKKGVEATYEEIAKTFGNIDIVVNVAGI--------FNDKDVQRTLLVNLGGII 121 Query: 121 RMLQAFLPDMKRRGSGR---VLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVL--LL 175 + LP M + G+ V+ SV GL + VY A+K + LA Sbjct: 122 NSTLSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQ 181 Query: 176 PFGVHLSLIECGPVHTAF 193 G+ + G T Sbjct: 182 RSGIKFVTVCPGATMTDM 199 >4EGF-A nrPDB Length = 266 Score = 135 bits (340), Expect = 3e-32, Method: Composition-based stats. Identities = 51/246 (20%), Positives = 87/246 (35%), Gaps = 23/246 (9%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + LITG + GIG +A A+ ++ + +L R + Sbjct: 18 LDGKRALITGATKGIGADIARAFAAAGARLVLSGRDVSELDAARRALG-----EQFGTDV 72 Query: 61 ETLQLDVRDSKS--VAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 T+ +D+ + + A R G +DVLV NAG+ P+ + + VN+ Sbjct: 73 HTVAIDLAEPDAPAELARRAAEAFGGLDVLVNNAGISHPQPVVDTDPQLFDATIAVNLRA 132 Query: 119 TVRMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 + A M G G ++ S L LP + YC SK L + LA L P Sbjct: 133 PALLASAVGKAMVAAGEGGAIITVASAAALAPLPDHYAYCTSKAGLVMATKVLARELGPH 192 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV 237 G+ + + V T ++V G + ++ P EV Sbjct: 193 GIRANSVCPTVVLTEMGQRVWGDE---------------AKSAPMIARIPLGRFAVPHEV 237 Query: 238 AEVFLT 243 ++ + Sbjct: 238 SDAVVW 243 >2BGM-A nrPDB Length = 278 Score = 133 bits (335), Expect = 9e-32, Method: Composition-based stats. Identities = 43/227 (18%), Positives = 77/227 (33%), Gaps = 24/227 (10%) Query: 20 AVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAARER 79 A ++ V A + D Q P + + DV + V + Sbjct: 33 AKLFVRYGAKV--VIADIADDHGQKVCNNI-----GSPDVISFVHCDVTKDEDVRNLVDT 85 Query: 80 --VTEGRVDVLVCNAGLGLLGP--LEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGS 135 G++D++ N G+ P + G + V+D+NV G + + M Sbjct: 86 TIAKHGKLDIMFGNVGVLSTTPYSILEAGNEDFKRVMDINVYGAFLVAKHAARVMIPAKK 145 Query: 136 GRVLVTGSVGGLMGLPFNDV-YCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFM 194 G ++ T S+ Y A+K A+ GL SL L +G+ ++ + V + + Sbjct: 146 GSIVFTASISSFTAGEGVSHVYTATKHAVLGLTTSLCTELGEYGIRVNCVSPYIVASPLL 205 Query: 195 EKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVF 241 V G + LAH + E+VA+ Sbjct: 206 TDVFGVDSSR------------VEELAHQAANLKGTLLRAEDVADAV 240 >4HBG-A nrPDB Length = 286 Score = 132 bits (331), Expect = 3e-31, Method: Composition-based stats. Identities = 51/277 (18%), Positives = 91/277 (32%), Gaps = 59/277 (21%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQG-RLWEAARALACPPGSLETL 63 V ++TG + GIG + +L + +T ++ + L+ + Sbjct: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 Query: 64 Q-------LDVRDSKSVAAARERVTEGR--------------------VDVLVCNAGLGL 96 LD + ++R + V++L+ AGL Sbjct: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 Query: 97 LGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRG------SG-----RVLVTGSV- 144 + +++VN + V M + M + SG ++ S+ Sbjct: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 Query: 145 -GGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVH-TAFMEKVLGSPE 202 G M +P VY ASK AL E LA + P + I G V T ++ + + Sbjct: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 Query: 203 EVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE 239 E+L+RT + P E+AE Sbjct: 246 EMLERTIGAS-----------------GTSAPAEIAE 265 >5JY1-A nrPDB Length = 274 Score = 130 bits (328), Expect = 7e-31, Method: Composition-based stats. Identities = 51/266 (19%), Positives = 90/266 (33%), Gaps = 21/266 (7%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + + V L+TG GIG +A ++ + + + + + G Sbjct: 12 LEQRVALVTGAGGGIGRGVARSFGNEGAAVIIAEIN------ESTGRQVEQEIREMGGRS 65 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGL-GLLGPLEALGEDAVASVLDVNVV 117 ++ DV S+ AA E G +D+LV NA + LE ++ + L ++ Sbjct: 66 LFVKTDVTSKASIEAAVRSAVEQFGSLDILVNNAFVPTPNVLLEEKTDEMLEQTLTTSLW 125 Query: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177 T ++A M+ R GR++ S+ G + Y +K + GL S A F Sbjct: 126 ATWWAMRAAFVPMRERRWGRIVNFYSIDTETGAWLHGDYNTAKAGIVGLTRSAASEWGRF 185 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV 237 + ++ I + F E +PE R Sbjct: 186 NITVNAIAPTAMGATFFELAAKNPEFAERSAAARPLGRSGDPEQDIGP------------ 233 Query: 238 AEVFLTALRAPKPTLRYFTTERFLPL 263 A VF + + T + L L Sbjct: 234 AAVFFASEMSRFVTGETLHVDGGLHL 259 >4DA9-A nrPDB Length = 280 Score = 130 bits (327), Expect = 7e-31, Method: Composition-based stats. Identities = 65/274 (23%), Positives = 101/274 (36%), Gaps = 30/274 (10%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 AR V ++TG GIGL +A LA+ + + L+ + Sbjct: 28 ARPVAIVTGGRRGIGLGIARALAASGFDIAIT-----GIGDAEGVAPVIAELSGLGARVI 82 Query: 62 TLQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGP--LEALGEDAVASVLDVNVV 117 L+ D+ D S A + V GR+D LV NAG+ + L + +++ VN+ Sbjct: 83 FLRADLADLSSHQATVDAVVAEFGRIDCLVNNAGIASIVRDDFLDLKPENFDTIVGVNLR 142 Query: 118 GTVRMLQAFLPDMKR---RGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLL 174 GTV QA L M R S ++ SV +M P YC SK L + LA+ L Sbjct: 143 GTVFFTQAVLKAMLASDARASRSIINITSVSAVMTSPERLDYCMSKAGLAAFSQGLALRL 202 Query: 175 LPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNP 234 G+ + + G + + V G Y L S V P Sbjct: 203 AETGIAVFEVRPGIIRSDMTAAVSGK----------------YDGLIESGLVPMRRWGEP 246 Query: 235 EEVAEVF--LTALRAPKPTLRYFTTERFLPLLRM 266 E++ + L + T + L + R+ Sbjct: 247 EDIGNIVAGLAGGQFGFATGSVIQADGGLSIGRL 280 >3U4C-A nrPDB Length = 281 Score = 128 bits (321), Expect = 4e-30, Method: Composition-based stats. Identities = 49/266 (18%), Positives = 105/266 (39%), Gaps = 18/266 (6%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 M++ + G S GIG +A++LA L ++++ A P S+ Sbjct: 21 MSKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAK----HPEASV 76 Query: 61 ETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 L D+ D + A +++ GR+DVL+ N G + + + + V Sbjct: 77 IVLAGDMSDQHTRAGIFQKIESQCGRLDVLINNIPGGAPDTFDNCNIEDMTATFTQKTVA 136 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCAS--KFALEGLCESLAVLLLP 176 + ++ MK+ GR++ VG L P +++ S AL +++++ L P Sbjct: 137 YIDAIKRASSLMKQNEFGRIINI--VGNLWKEPGANMFTNSMMNAALINASKNISIQLAP 194 Query: 177 FGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEE 236 + ++ + G + T + + E V+ + ++ + + + + + EE Sbjct: 195 HNITVNCLNPGFIATDRYHQFV---ENVMKK---NSISKQKAEEQIASGIPMKRVGSAEE 248 Query: 237 VA--EVFLTALRAPKPTLRYFTTERF 260 A FL + A T + + + Sbjct: 249 TAALAAFLASEEASYITGQQISADGG 274 >4DRY-A nrPDB Length = 281 Score = 127 bits (319), Expect = 7e-30, Method: Composition-based stats. Identities = 45/185 (24%), Positives = 73/185 (39%), Gaps = 12/185 (6%) Query: 19 LAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE-TLQLDVRDSKSVAA-- 75 +A L+++ L AA + G++ + DV D VAA Sbjct: 49 IAQALSAEGYSVVITGR------RPDVLDAAAGEIGGRTGNIVRAVVCDVGDPDQVAALF 102 Query: 76 ARERVTEGRVDVLVCNAGLG-LLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRR- 133 A R R+D+LV NAG PLE + + ++ N+ G Q MK + Sbjct: 103 AAVRAEFARLDLLVNNAGSNVPPVPLEEVTFEQWNGIVAANLTGAFLCTQHAFRMMKAQT 162 Query: 134 -GSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTA 192 GR++ GS+ P + Y A+K A+ GL +S A+ + I+ G T Sbjct: 163 PRGGRIINNGSISAQTPRPNSAPYTATKHAITGLTKSTALDGRMHDIACGQIDIGNAATD 222 Query: 193 FMEKV 197 ++ Sbjct: 223 MTARM 227 >1SNY-A nrPDB Length = 267 Score = 127 bits (319), Expect = 7e-30, Method: Composition-based stats. Identities = 50/207 (24%), Positives = 90/207 (43%), Gaps = 23/207 (11%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 +LITGC+ G+GL L L + P ++ T R+ + L + A+ + ++ L++ Sbjct: 24 ILITGCNRGLGLGLVKALLNLPQPPQHLFTTCRNREQAKELEDLAKNHS----NIHILEI 79 Query: 66 DVRDSKSVAAARERVT----EGRVDVLVCNAGLGL-LGPLEALGEDAVASVLDVNVVGTV 120 D+R+ + + + ++VL NAG+ + A+ + L N V + Sbjct: 80 DLRNFDAYDKLVADIEGVTKDQGLNVLFNNAGIAPKSARITAVRSQELLDTLQTNTVVPI 139 Query: 121 RMLQAFLPDMKRR---------GSGR--VLVTGSVGG-LMGLPFNDVYC--ASKFALEGL 166 + +A LP +K+ G GR ++ S+ G + G +Y SK AL Sbjct: 140 MLAKACLPLLKKAAKANESQPMGVGRAAIINMSSILGSIQGNTDGGMYAYRTSKSALNAA 199 Query: 167 CESLAVLLLPFGVHLSLIECGPVHTAF 193 +SL+V L P + + G V T Sbjct: 200 TKSLSVDLYPQRIMCVSLHPGWVKTDM 226 >3BHI-A nrPDB Length = 276 Score = 126 bits (317), Expect = 1e-29, Method: Composition-based stats. Identities = 65/278 (23%), Positives = 91/278 (32%), Gaps = 57/278 (20%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 V L+TG + GIGL + L S V T RD+ R A + L S Q Sbjct: 6 VALVTGGNKGIGLAIVRDLCRLFSG--DVVLTARDVT---RGQAAVQQLQAEGLSPRFHQ 60 Query: 65 LDVRDSKSVAAARE--RVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 LD+ D +S+ A R+ R G +DVLV NAG+ + N GT + Sbjct: 61 LDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDV 120 Query: 123 LQAFLPDMKRRGSGRVLVTGSV---------------------------GGLM------- 148 LP +K + GRV+ S+ GLM Sbjct: 121 CTELLPLIKPQ--GRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDT 178 Query: 149 --------GLPFNDVYCASKFALEGLCESLAVLLL----PFGVHLSLIECGPVHTAFME- 195 G P + Y +K + L A L + L+ G V T Sbjct: 179 KKGVHQKEGWP-SSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGP 237 Query: 196 KVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQN 233 K SPEE + H + V + + Sbjct: 238 KATKSPEEGAETPVYLALLPPDAEGPHGQFVSEKRVEQ 275 >1N5D-A nrPDB Length = 288 Score = 126 bits (317), Expect = 1e-29, Method: Composition-based stats. Identities = 56/283 (19%), Positives = 84/283 (29%), Gaps = 59/283 (20%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETL 63 V L+TG + GIG + L + V T RD+ R A + L S Sbjct: 5 RVALVTGANKGIGFAIVRDLCRQFAG--DVVLTARDV---ARGQAAVKQLQAEGLSPRFH 59 Query: 64 QLDVRDSKSVAAARE--RVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 QLD+ D +S+ A + R G +DVLV NA + + N +GT Sbjct: 60 QLDIIDLQSIRALCDFLRKEYGGLDVLVNNAAIAFQLDNPTPFHIQAELTMKTNFMGTRN 119 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDV-------------------------- 155 + LP +K + GRV+ S G+ L Sbjct: 120 VCTELLPLIKPQ--GRVVNVSSTEGVRALNECSPELQQKFKSETITEEELVGLMNKFVED 177 Query: 156 ---------------YCASKFALEGLCESLAVLL----LPFGVHLSLIECGPVHTAFMEK 196 Y +K + L A L + L+ G V T Sbjct: 178 TKNGVHRKEGWSDSTYGVTKIGVSVLSRIYARKLREQRAGDKILLNACCPGWVRTDM--- 234 Query: 197 VLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE 239 G P+ + L + ++V E Sbjct: 235 --GGPKAPKSPEVGAETPVYLALLPSDAEGPHGQFVTDKKVVE 275 >3U9L-A nrPDB Length = 324 Score = 124 bits (311), Expect = 6e-29, Method: Composition-based stats. Identities = 64/197 (32%), Positives = 102/197 (51%), Gaps = 8/197 (4%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDL--KTQGRLWEAARALACPPG 58 M++ ++LITG SSG G A LA +VYA++RD+ + + A Sbjct: 3 MSKKIILITGASSGFGRLTAEALAGAG---HRVYASMRDIVGRNASNVEAIAGFARDNDV 59 Query: 59 SLETLQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNV 116 L TL+LDV+ SV A +++ +GR+DVL+ NAG + GP EA + A + D+NV Sbjct: 60 DLRTLELDVQSQVSVDRAIDQIIGEDGRIDVLIHNAGHMVFGPAEAFTPEQFAELYDINV 119 Query: 117 VGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGL-PFNDVYCASKFALEGLCESLAVLLL 175 + T R+ +A LP M+R+ G ++ S G P+ Y A+K A++ + A L Sbjct: 120 LSTQRVNRAALPHMRRQKHGLLIWISSSSSAGGTPPYLAPYFAAKAAMDAIAVQYARELS 179 Query: 176 PFGVHLSLIECGPVHTA 192 +G+ S+I G + Sbjct: 180 RWGIETSIIVPGAFTSG 196 >3KZV-A nrPDB Length = 254 Score = 122 bits (307), Expect = 2e-28, Method: Composition-based stats. Identities = 45/194 (23%), Positives = 72/194 (37%), Gaps = 13/194 (6%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 62 V+L+TG S GIG + L S + VY R +L E Sbjct: 2 GKVILVTGVSRGIGKSIVDVLFSL-DKDTVVYGVARSEAPLKKLKE------KYGDRFFY 54 Query: 63 LQLDVRDSKSVAAARERVT--EGRVDVLVCNAGL-GLLGPLEALGEDAVASVLDVNVVGT 119 + D+ + + G++D LV NAG+ + + + +A + D+N Sbjct: 55 VVGDITEDSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNEIDVNAWKKLYDINFFSI 114 Query: 120 VRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGV 179 V ++ LP++K+ G V+ S M Y +SK AL +LA V Sbjct: 115 VSLVGIALPELKKTN-GNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANE--ERQV 171 Query: 180 HLSLIECGPVHTAF 193 + G V T Sbjct: 172 KAIAVAPGIVDTDM 185 >2X9N-A nrPDB Length = 288 Score = 115 bits (289), Expect = 2e-26, Method: Composition-based stats. Identities = 55/287 (19%), Positives = 98/287 (34%), Gaps = 44/287 (15%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGS- 59 M ++TG + IG +AV+L + Y + A L + Sbjct: 21 MEAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVS-----LADELNKERSNT 75 Query: 60 LETLQLDVRDSKSVAAARERV------TEGRVDVLVCNAGLGLLGPLEALGEDA------ 107 Q D+ +S + A+ E + GR DVLV NA PL + Sbjct: 76 AVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDNSNGKT 135 Query: 108 ----VASVLDVNVVGTVRMLQAFLPDMKR------RGSGRVLVTGSVGGLMGLPFNDVYC 157 VA ++ N + + +F K + ++ +Y Sbjct: 136 VETQVAELIGTNAIAPFLLTMSFAQRQKGTNPNCTSSNLSIVNLCDAMVDQPCMAFSLYN 195 Query: 158 ASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFY 217 K AL GL +S A+ L P+G+ ++ + G + + +G E+ R + Sbjct: 196 MGKHALVGLTQSAALELAPYGIRVNGVAPGV---SLLPVAMGEEEKDKWRRKV----PLG 248 Query: 218 QYLAHSKQVFREAAQNPEEVAEVFLTALRAPKPTLRYFTTERFLPLL 264 + A ++Q+ A +FL + A T + L L+ Sbjct: 249 RREASAEQIAD---------AVIFLVSGSAQYITGSIIKVDGGLSLV 286 >4GKB-A nrPDB Length = 258 Score = 114 bits (286), Expect = 5e-26, Method: Composition-based stats. Identities = 64/264 (24%), Positives = 103/264 (39%), Gaps = 23/264 (8%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + VV++TG +SGIG +++RLA + + D ALA Sbjct: 5 LQDKVVIVTGGASGIGGAISMRLAEERAIPVVFARHAPD-------GAFLDALAQRQPRA 57 Query: 61 ETLQLDVRDSKSVAAARER--VTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 L ++++D A + T GR+D LV NAG+ G G DA + L+ N++ Sbjct: 58 TYLPVELQDDAQCRDAVAQTIATFGRLDGLVNNAGVN-DGIGLDAGRDAFVASLERNLIH 116 Query: 119 TVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFG 178 M +P +K G ++ S + G YCASK A L AV L G Sbjct: 117 YYAMAHYCVPHLKATR-GAIVNISSKTAVTGQGNTSGYCASKGAQLALTREWAVALREHG 175 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 238 V ++ + V T + + E+ + +K P+E+A Sbjct: 176 VRVNAVIPAEVMTPLYRNWIATFEDPEAKLAEIA----------AKVPLGRRFTTPDEIA 225 Query: 239 E--VFLTALRAPKPTLRYFTTERF 260 + VFL + RA T + + Sbjct: 226 DTAVFLLSPRASHTTGEWLFVDGG 249 >1W73-A nrPDB Length = 302 Score = 109 bits (273), Expect = 1e-24, Method: Composition-based stats. Identities = 44/243 (18%), Positives = 85/243 (34%), Gaps = 24/243 (9%) Query: 23 LASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAARERVTE 82 L+S +Q + LK + + + +Q DVRD V + + Sbjct: 46 LSSLGAQCVIASRKMDVLKATAE-----QISSQTGNKVHAIQCDVRDPDMVQNTVSELIK 100 Query: 83 --GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGR-VL 139 G ++++ NA + P E L +A ++ D+ + GT + + + G L Sbjct: 101 VAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFL 160 Query: 140 VTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLG 199 ++ G F ++K +E + +SLA +G+ ++I+ GP+ T L Sbjct: 161 SITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRL- 219 Query: 200 SPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE--VFLTALRAPKPTLRYFTT 257 P ++ I + EE+A FL + A Sbjct: 220 DPTGTFEKEMIGR-------------IPCGRLGTVEELANLAAFLCSDYASWINGAVIKF 266 Query: 258 ERF 260 + Sbjct: 267 DGG 269 >3PPI-A nrPDB Length = 281 Score = 109 bits (272), Expect = 2e-24, Method: Composition-based stats. Identities = 52/275 (18%), Positives = 86/275 (31%), Gaps = 45/275 (16%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 +++G + G+G RL +D K E + Sbjct: 33 AIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADEL---------GNRAEFVST 83 Query: 66 DVRDSKSVAAARERVTE-GRVDVLVCNAG--------LGLLGPLEALGEDAVASVLDVNV 116 +V SV AA E + GR+ V G + G +G +D+ + Sbjct: 84 NVTSEDSVLAAIEAANQLGRLRYAVVAHGGFGVAQRIVQRDGSPADMG--GFTKTIDLYL 141 Query: 117 VGTVRMLQ------AFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170 GT + + A + G +++T S+ G G Y A+K + GL + Sbjct: 142 NGTYNVARLVAASIAAAEPRENGERGALVLTASIAGYEGQIGQTAYAAAKAGVIGLTIAA 201 Query: 171 AVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREA 230 A L G+ ++ I G + T ME V +F + K Sbjct: 202 ARDLSSAGIRVNTIAPGTMKTPIMESV-----------GEEALAKFAANIPFPK-----R 245 Query: 231 AQNPEEVAEVFLTALRAPKPTLRYF---TTERFLP 262 P+E A+ L +RF P Sbjct: 246 LGTPDEFADAAAFLLTNGYINGEVMRLDGAQRFTP 280 >2BFA-A nrPDB Length = 288 Score = 105 bits (261), Expect = 4e-23, Method: Composition-based stats. Identities = 60/299 (20%), Positives = 97/299 (32%), Gaps = 57/299 (19%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVY------ATLRDLKTQGRLWEAARALACPPG 58 V L+TG + +G +A L ++ Y A R +A + Sbjct: 8 VALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLS 67 Query: 59 SLETLQLDVRDSKSVAAARERVTE---------GRVDVLVCNAGLGLLGPLEALGED--- 106 ++ T + D + R E GR DVLV NA PL ED Sbjct: 68 NVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHE 127 Query: 107 -----------AVASVLDVNVVGTVRMLQAFLPDMK---RRGSG---RVLVTGSVGGLMG 149 A A + N + +++AF + + G ++ Sbjct: 128 PCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQP 187 Query: 150 LPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTD 209 L +Y +K ALEGL S A+ L P + ++ + G V P V + Sbjct: 188 LLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPG-----LSVLVDDMPPAVWE--- 239 Query: 210 IHTFHRFYQYLAHSKQVFR-EAAQNPEEVAEV--FLTALRAPKPTLRYFTTERFLPLLR 265 H +V + + EV++V FL + +A T + L R Sbjct: 240 -----------GHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLTR 287 >2QHX-A nrPDB Length = 328 Score = 104 bits (260), Expect = 4e-23, Method: Composition-based stats. Identities = 60/299 (20%), Positives = 97/299 (32%), Gaps = 57/299 (19%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVY------ATLRDLKTQGRLWEAARALACPPG 58 V L+TG + +G +A L ++ Y A R +A + Sbjct: 48 VALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLS 107 Query: 59 SLETLQLDVRDSKSVAAARERVTE---------GRVDVLVCNAGLGLLGPLEALGED--- 106 ++ T + D + R E GR DVLV NA PL ED Sbjct: 108 NVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHE 167 Query: 107 -----------AVASVLDVNVVGTVRMLQAFLPDMK---RRGSG---RVLVTGSVGGLMG 149 A A + N + +++AF + + G ++ Sbjct: 168 PCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQP 227 Query: 150 LPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTD 209 L +Y +K ALEGL S A+ L P + ++ + G V P V + Sbjct: 228 LLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPG-----LSVLVDDMPPAVWE--- 279 Query: 210 IHTFHRFYQYLAHSKQVFR-EAAQNPEEVAEV--FLTALRAPKPTLRYFTTERFLPLLR 265 H +V + + EV++V FL + +A T + L R Sbjct: 280 -----------GHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLTR 327 >5L51-A nrPDB Length = 324 Score = 104 bits (260), Expect = 5e-23, Method: Composition-based stats. Identities = 46/271 (16%), Positives = 77/271 (28%), Gaps = 82/271 (30%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 + ++TG + GIG + +LAS + R + + Sbjct: 14 TKRYAVVTGANKGIGFEICKQLASKGITVILASRD-EKRGIEARERLIKELGSEFGDYVV 72 Query: 62 TLQLDVRDSKSVAAARE--RVTEGRVDVLVCNAGLG------LLGPLEALGEDAVASV-- 111 + QLDV D SVAA + + G +D+LV NAGL L E + Sbjct: 73 SQQLDVADPASVAALVDFIKTKFGSLDILVNNAGLNGTYMEGDASVLNDYVEAEFKTFQS 132 Query: 112 --------------------------LDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVG 145 ++ N G+ R+ +A +P +++ S R++ S Sbjct: 133 GAAKTEPYHPKATGRLVETVEHAKECIETNYYGSKRVTEALIPLLQQSDSPRIVNVSSTL 192 Query: 146 GLMGL-------------------------------------------PFNDVYCASKFA 162 + P Y SK A Sbjct: 193 SSLVFQTNEWAKGVFSSEEGLTEEKLEEVLAEFLKDFIDGKQQEKQWPPHFSAYKVSKAA 252 Query: 163 LEGLCESLAVLLLPFGVHLSLIECGPVHTAF 193 L +A F ++ + G T Sbjct: 253 LNAYTRIIAKKYPSF--RINAVCPGYTKTDL 281 >1B15-A nrPDB Length = 254 Score = 104 bits (259), Expect = 6e-23, Method: Composition-based stats. Identities = 45/197 (22%), Positives = 73/197 (37%), Gaps = 18/197 (9%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 62 + V+ + GIGL + L ++ K + L ++ L E + T Sbjct: 6 KNVIFV-AALGGIGLDTSRELVK---RNLKNFVILDRVENPTALAELKAINPKVNITFHT 61 Query: 63 LQLDVRDSKSVAAARERVTE-GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 + V ++S ++ + VD+L+ AG+ L + + + +N G V Sbjct: 62 YDVTVPVAESKKLLKKIFDQLKTVDILINGAGI--------LDDHQIERTIAINFTGLVN 113 Query: 122 MLQAFLPDMKRRGSG---RVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLP-F 177 A L +R G + SV G + VY ASK A+ SLA L P Sbjct: 114 TTTAILDFWDKRKGGPGGIIANICSVTGFNAIHQVPVYSASKAAVVSFTNSLAK-LAPIT 172 Query: 178 GVHLSLIECGPVHTAFM 194 GV I G T + Sbjct: 173 GVTAYSINPGITRTPLV 189 >3O26-A nrPDB Length = 311 Score = 102 bits (254), Expect = 2e-22, Method: Composition-based stats. Identities = 50/268 (18%), Positives = 83/268 (30%), Gaps = 83/268 (30%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 R ++TG + GIG + +L+S+ V T RD+ E + ++ Sbjct: 11 KRRCAVVTGGNKGIGFEICKQLSSNG---IMVVLTCRDVTKGHEAVEKLKNSNHE--NVV 65 Query: 62 TLQLDVRDSKSVA---AARERVTEGRVDVLVCNAGLG--------LLGPLEALGEDAVAS 110 QLDV D + A + G++D+LV NAG+ + +GED+ Sbjct: 66 FHQLDVTDPIATMSSLADFIKTHFGKLDILVNNAGVAGFSVDADRFKAMISDIGEDSEEL 125 Query: 111 V----------------------LDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLM 148 V L +N G + + +P ++ S R++ S G + Sbjct: 126 VKIYEKPEAQELMSETYELAEECLKINYNGVKSVTEVLIPLLQLSDSPRIVNVSSSTGSL 185 Query: 149 ------------------------------------------GLPF-NDVYCASKFALEG 165 G P Y SK L Sbjct: 186 KYVSNETALEILGDGDALTEERIDMVVNMLLKDFKENLIETNGWPSFGAAYTTSKACLNA 245 Query: 166 LCESLAVLLLPFGVHLSLIECGPVHTAF 193 LA + F ++ + G V T Sbjct: 246 YTRVLANKIPKFQ--VNCVCPGLVKTEM 271 >2P91-A nrPDB Length = 285 Score = 101 bits (253), Expect = 3e-22, Method: Composition-based stats. Identities = 51/268 (19%), Positives = 92/268 (34%), Gaps = 29/268 (10%) Query: 1 MARTVVLITGCS--SGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPG 58 + LITG + I +A + +Q YAT + L + R +A G Sbjct: 19 LEGKRALITGVANERSIAYGIAKSFHREGAQLAFTYATPK-------LEKRVREIAKGFG 71 Query: 59 SLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLE----ALGEDAVASVL 112 S ++ DV + + ++ + E G +D++V + + + + Sbjct: 72 SDLVVKCDVSLDEDIKNLKKFLEENWGSLDIIVHSIAYAPKEEFKGGVIDTSREGFKIAM 131 Query: 113 DVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAV 172 D++V + + + LP M +G ++ G +P +V +K ALE LA Sbjct: 132 DISVYSLIALTRELLPLM-EGRNGAIVTLSYYGAEKVVPHYNVMGIAKAALESTVRYLAY 190 Query: 173 LLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQ 232 + G ++ I GPV T L I FH ++ + Sbjct: 191 DIAKHGHRINAISAGPVKT-------------LAAYSITGFHLLMEHTTKVNPFGKPITI 237 Query: 233 NPEEVAEVFLTALRAPKPTLRYFTTERF 260 VFL + A T + Sbjct: 238 EDVGDTAVFLCSDWARAITGEVVHVDNG 265 >1P33-A nrPDB Length = 289 Score = 98.5 bits (244), Expect = 3e-21, Method: Composition-based stats. Identities = 55/299 (18%), Positives = 97/299 (32%), Gaps = 57/299 (19%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQS------FKVYATLRDLKTQGRLWEAARALACPPG 58 V L+TG + +G +A L ++ A+ R +A + Sbjct: 9 VALVTGAAKRLGSSIAEALHAEGYTVCLHYHRSAADASTLAATLNARRPNSAITVQADLS 68 Query: 59 SLETLQLDVRDSKSVAAARERVTE---------GRVDVLVCNAGLGLLGPLEALG----- 104 ++ T D R + GR DVLV NA PL Sbjct: 69 NVATASFSETDGSVPVTLFSRCSALVDACYMHWGRCDVLVNNASSFYPTPLLRKDAGEGG 128 Query: 105 ---------EDAVASVLDVNVVGTVRMLQAFLPDM---KRRGSG---RVLVTGSVGGLMG 149 E A A + N + +++AF + + G ++ Sbjct: 129 SSVGDKESLEVAAADLFGSNAIAPYFLIKAFAQRVADTRAEQRGTSYSIVNMVDAMTSQP 188 Query: 150 LPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTD 209 L +Y +K ALEGL S A+ L + ++ + G + P+++ Sbjct: 189 LLGYTMYTMAKEALEGLTRSAALELASLQIRVNGVSPG---------LSVLPDDM----- 234 Query: 210 IHTFHRFYQYLAHSKQVFR-EAAQNPEEVAEV--FLTALRAPKPTLRYFTTERFLPLLR 265 F + ++V + + EEV++V FL + +A T + L R Sbjct: 235 -----PFSVQEDYRRKVPLYQRNSSAEEVSDVVIFLCSPKAKYITGTCIKVDGGYSLTR 288 >2YW9-A nrPDB Length = 261 Score = 98.5 bits (244), Expect = 4e-21, Method: Composition-based stats. Identities = 59/279 (21%), Positives = 97/279 (34%), Gaps = 34/279 (12%) Query: 1 MARTVVLITGCS--SGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPG 58 ++ L+ G + +G +A +L ++ Y RL A LA G Sbjct: 6 LSGKKALVMGVTNQRSLGFAIAAKLKEAGAEVALSY-------QAERLRPEAEKLAEALG 58 Query: 59 SLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLE----ALGEDAVASVL 112 + DV + + A V E G +D LV +E L Sbjct: 59 GALLFRADVTQDEELDALFAGVKEAFGGLDYLVHAIAFAPREAMEGRYIDTRRQDWLLAL 118 Query: 113 DVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAV 172 +V+ V + + P ++ G ++ +P +V +K ALE LA Sbjct: 119 EVSAYSLVAVARRAEPLLREGGG--IVTLTYYASEKVVPKYNVMAIAKAALEASVRYLAY 176 Query: 173 LLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQ 232 L P GV ++ I GPV T + G F + Y +A + + R Q Sbjct: 177 ELGPKGVRVNAISAGPVRTVAARSIPG-------------FTKMYDRVAQTAPLRRNITQ 223 Query: 233 NPEEVAE--VFLTALRAPKPTLRYFTTERFLPLLRMRLD 269 EEV +FL + A T + ++ M L+ Sbjct: 224 --EEVGNLGLFLLSPLASGITGEVVYVDAGYHIMGMELE 260 >1MG5-A nrPDB Length = 255 Score = 94.7 bits (234), Expect = 5e-20, Method: Composition-based stats. Identities = 48/220 (21%), Positives = 77/220 (35%), Gaps = 25/220 (11%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 62 + V+ + G GIGL + L + K L ++ + E P ++ Sbjct: 7 KNVIFVAGLG-GIGLDTSKELLK---RDLKNLVILDRIENPAAIAELKAI--NPKVTVTF 60 Query: 63 LQLDVRDSKSVAAARERVTEGRV---DVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGT 119 DV + + ++ DVL+ AG+ L + + + VN G Sbjct: 61 YPYDVTVPIAETTKLLKTIFAQLKTVDVLINGAGI--------LDDHQIERTIAVNYTGL 112 Query: 120 VRMLQAFLPDMKRRGSG---RVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLP 176 V A L +R G + GSV G + VY +K A+ SLA L P Sbjct: 113 VNTTTAILDFWDKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAK-LAP 171 Query: 177 -FGVHLSLIECGPVHTAFMEKV---LGSPEEVLDRTDIHT 212 GV + G T + K L +V ++ H Sbjct: 172 ITGVTAYTVNPGITRTTLVHKFNSWLDVEPQVAEKLLAHP 211 >4HWK-A nrPDB Length = 288 Score = 92.4 bits (228), Expect = 2e-19, Method: Composition-based stats. Identities = 44/207 (21%), Positives = 74/207 (35%), Gaps = 16/207 (7%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + R V L+TG S G G LA LAS S + + R+ R EA + Sbjct: 32 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARN-DEALRQLEAELGAERSGLRV 90 Query: 61 ETLQLDVRDSKSVAAARERVTE-------GRVDVLVCNAGLGLL---GPLEALGEDAVAS 110 + D+ + + E R+ +L+ NAG G ++ V + Sbjct: 91 VRVPADLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNN 149 Query: 111 VLDVNVVGTVRMLQAFLPDMKRRGSGR--VLVTGSVGGLMGLPFNDVYCASKFALEGLCE 168 +N+ + + + L V+ S+ L +YCA K A + L + Sbjct: 150 YWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQ 209 Query: 169 SLAVLLLPFGVHLSLIECGPVHTAFME 195 LA+ V + GP+ T + Sbjct: 210 VLALE--EPNVRVLNYAPGPLDTDMQQ 234 >4Z3K-A nrPDB Length = 275 Score = 92.4 bits (228), Expect = 2e-19, Method: Composition-based stats. Identities = 44/207 (21%), Positives = 74/207 (35%), Gaps = 16/207 (7%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + R V L+TG S G G LA LAS S + + R+ R EA + Sbjct: 19 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARN-DEALRQLEAELGAERSGLRV 77 Query: 61 ETLQLDVRDSKSVAAARERVTE-------GRVDVLVCNAGLGLL---GPLEALGEDAVAS 110 + D+ + + E R+ +L+ NAG G ++ V + Sbjct: 78 VRVPADLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNN 136 Query: 111 VLDVNVVGTVRMLQAFLPDMKRRGSGR--VLVTGSVGGLMGLPFNDVYCASKFALEGLCE 168 +N+ + + + L V+ S+ L +YCA K A + L + Sbjct: 137 YWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQ 196 Query: 169 SLAVLLLPFGVHLSLIECGPVHTAFME 195 LA+ V + GP+ T + Sbjct: 197 VLALE--EPNVRVLNYAPGPLDTDMQQ 221 >1OAA-A nrPDB Length = 259 Score = 92.0 bits (227), Expect = 3e-19, Method: Composition-based stats. Identities = 44/222 (19%), Positives = 76/222 (34%), Gaps = 16/222 (7%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 V ++TG S G G LA +LA S + + R +L E A P + Sbjct: 8 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGA-QQPDLKVVLAA 66 Query: 65 LDVRDSKSVAAARERVTE-------GRVDVLVCNAGLGLLGPLEALGEDAVASVLD---V 114 D+ V V E R+ +L+ NA L + +A V + + Sbjct: 67 ADLGTEAGVQRLLSAVRELPRPEGLQRL-LLINNAATLGDVSKGFLNVNDLAEVNNYWAL 125 Query: 115 NVVGTVRMLQAFLPDMKRRGSGR--VLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAV 172 N+ + + L + V+ S+ L +YCA K A + L + LA Sbjct: 126 NLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAA 185 Query: 173 LLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFH 214 V + GP+ + + ++ R+ + Sbjct: 186 EEPS--VRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLK 225 >5KOI-A nrPDB Length = 293 Score = 88.5 bits (218), Expect = 4e-18, Method: Composition-based stats. Identities = 43/181 (23%), Positives = 69/181 (38%), Gaps = 16/181 (8%) Query: 18 HLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAAR 77 +A +LA+ ++ Y L + + LA GS L DV D +V A Sbjct: 45 GIAKQLAAQGAELAFTY-------QGDALGKRVKPLAEQVGSDFVLPCDVEDIATVDAVF 97 Query: 78 ERVTE--GRVDVLVCNAGLGLLGPL-----EALGEDAVASVLDVNVVGTVRMLQAFLPDM 130 E + + G +D LV G L + + + + ++ + Q M Sbjct: 98 EEIEKKWGGLDFLVHAIGFSDKTELKGRYADVTTRENFSRTMVISAYSFTEVAQRAEKLM 157 Query: 131 KRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVH 190 K G +L G +P +V +K ALE + LA P G+ ++ I GPV Sbjct: 158 KD--GGSILTLTYGGSTRTIPNYNVMGVAKAALEAMVRYLAADYGPQGIRVNAISAGPVR 215 Query: 191 T 191 T Sbjct: 216 T 216 >5LCX-A nrPDB Length = 316 Score = 86.6 bits (213), Expect = 1e-17, Method: Composition-based stats. Identities = 48/274 (17%), Positives = 79/274 (28%), Gaps = 86/274 (31%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 62 + L+TG + GIG + +LA + + + + + + L L Sbjct: 7 QRYALVTGANKGIGFEICRQLAEKG--IIVILTSRNEKRGLEARQKLLKELNVSENRLVF 64 Query: 63 LQLDVRDSKSVAAARERV--TEGRVDVLVCNAGLG------LLGPLEALGEDAVA----- 109 QLDV D SVAA + G++D+LV NAG+ + E Sbjct: 65 HQLDVTDLASVAAVAVFIKSKFGKLDILVNNAGVSGVEMVGDVSVFNEYIEADFKALQAL 124 Query: 110 ----------------SVLD----------VNVVGTVRMLQAFLPDMKRRGSGRVLVTGS 143 +++ N G R+ QA +P ++ S R++ S Sbjct: 125 EAGAKEEPPFKPKANGEMIEKFEGAKDCVVTNYYGPKRLTQALIPLLQLSPSPRIVNVSS 184 Query: 144 VG------------GLMG-------------------------------LPFNDVYCASK 160 G++G P SK Sbjct: 185 SFGSLLLLWNEWAKGVLGDEDRLTEERVDEVVEVFLKDIKEGKLEESQWPPHFAAERVSK 244 Query: 161 FALEGLCESLAVLLLPFGVHLSLIECGPVHTAFM 194 AL + A F ++ I G T Sbjct: 245 AALNAYTKIAAKKYPSF--RINAICPGYAKTDIT 276 >5TF4-A nrPDB Length = 274 Score = 86.2 bits (212), Expect = 2e-17, Method: Composition-based stats. Identities = 50/265 (18%), Positives = 92/265 (34%), Gaps = 28/265 (10%) Query: 12 SSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSK 71 + I +A +S ++ Y K L E + C DV DS Sbjct: 23 NRSIAWGIAKTASSAGAELAFTYQGEAMKKRVEPLAEEVKGFVCGH-------CDVSDSA 75 Query: 72 SVAAARERVTE--GRVDVLVCNAGLG----LLGPLEALGEDAVASVLDVNVVGTVRMLQA 125 S+ A + + G++D LV G L G + E ++++V + + Sbjct: 76 SIDAVFNTIEKKWGKLDFLVHAIGFSDKEELSGRYVDISESNFMMTMNISVYSLTALTKR 135 Query: 126 FLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIE 185 M G +L G +P +V +K ALE + LAV L P + ++ I Sbjct: 136 AEKLM--SDGGSILTLTYYGAEKVVPNYNVMGVAKAALEASVKYLAVDLGPKHIRVNAIS 193 Query: 186 CGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVFLTAL 245 GP+ T L + I F ++ ++ + R + ++L + Sbjct: 194 AGPIKT-------------LAASGIGDFRYILKWNEYNAPLRRTVTIEEVGDSALYLLSD 240 Query: 246 RAPKPTLRYFTTERFLPLLRMRLDD 270 + T + ++ M+ D Sbjct: 241 LSRSVTGEVHHVDSGYNIIGMKAVD 265 >5WQO-A nrPDB Length = 234 Score = 83.5 bits (205), Expect = 1e-16, Method: Composition-based stats. Identities = 48/193 (24%), Positives = 70/193 (36%), Gaps = 13/193 (6%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 VLI G S GIGL LA +Q F V + L E A L+ + Sbjct: 9 VLIVGASRGIGLGLADAFLQRGAQVFAVARRPQGSPGLQALAERA------GERLQAVTG 62 Query: 66 DVRDSKSVAAARERVTEGRVDVLVCNAGLG--LLGPLEALGEDAVASVLDVNVVGTVRML 123 D+ E + E R+D L+ NAG+ + + + A + N + +R+ Sbjct: 63 DLNQHDCAERIGEMLGERRIDRLIVNAGIYGPQQQDVAEIDAEQTAQLFLTNAIAPLRLA 122 Query: 124 QAFLPDMKRRGSGRVLVTGSVGGLMGLPFND---VYCASKFALEGLCESLAVLLLPFGVH 180 +A + G V S + L + +Y ASK AL L S Sbjct: 123 RALSG--RVSRGGVVAFMSSQMASLALGLSATMPLYGASKAALNSLVRSWEGEFEELPFS 180 Query: 181 LSLIECGPVHTAF 193 L L+ G V T Sbjct: 181 LLLLHPGWVRTEM 193 >5TQV-A nrPDB Length = 233 Score = 82.7 bits (203), Expect = 2e-16, Method: Composition-based stats. Identities = 46/236 (19%), Positives = 72/236 (30%), Gaps = 26/236 (11%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETL 63 VLI G S G+G + D L L Sbjct: 10 KTVLIVGASRGLGREFVRQYQRDGWNVIATARDDASLAALRAL------------GAHAH 57 Query: 64 QLDVRDSKSVAAARERVTEGRVDVLVCNAGLG--LLGPLEALGEDAVASVLDVNVVGTVR 121 LD+ + +AA ++ R+DV V +G+ +E + D +V+ NV G ++ Sbjct: 58 ALDITQPEQIAALGWKLDGERLDVAVVVSGVYGPRTEGVETIASDDFDTVMHTNVRGPMQ 117 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFND---VYCASKFALEGLCESLAVLLLPFG 178 +L LP + G + V S G + +Y ASK AL + + L Sbjct: 118 LLPILLP-LVEDARGVLAVVSSRMGSISEATGTTGWLYRASKAALNDVLRIAS--LQTRH 174 Query: 179 VHLSLIECGPVHTAFMEKVLGSPEEVLDRTD-IHTFHRFYQYLAHSKQVFREAAQN 233 + G V T G + LD + R Sbjct: 175 AACISLHPGWVRTDM-----GGAQAALDPATSVTGMRRVIAEAGADVSQSNGRFFQ 225 >3GRK-A nrPDB Length = 293 Score = 81.6 bits (200), Expect = 5e-16, Method: Composition-based stats. Identities = 47/265 (17%), Positives = 89/265 (33%), Gaps = 28/265 (10%) Query: 12 SSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSK 71 + I +A ++ Y L + LA G+ DV D+ Sbjct: 42 NRSIAWGIAKAAREAGAELAFTY-------QGDALKKRVEPLAEELGAFVAGHCDVADAA 94 Query: 72 SVAAARERVTE--GRVDVLVCNAGLGLLGPLE----ALGEDAVASVLDVNVVGTVRMLQA 125 S+ A E + + G++D LV G L E + + ++V + + Sbjct: 95 SIDAVFETLEKKWGKLDFLVHAIGFSDKDELTGRYIDTSEANFTNTMLISVYSLTAVSRR 154 Query: 126 FLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIE 185 M G +L G +P +V +K ALE + LAV L P + ++ I Sbjct: 155 AEKLM--ADGGSILTLTYYGAEKVMPNYNVMGVAKAALEASVKYLAVDLGPQNIRVNAIS 212 Query: 186 CGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVFLTAL 245 GP+ T L + I F ++ ++ + R + ++ + Sbjct: 213 AGPIKT-------------LAASGIGDFRYILKWNEYNAPLRRTVTIDEVGDVGLYFLSD 259 Query: 246 RAPKPTLRYFTTERFLPLLRMRLDD 270 + T + ++ M+ D Sbjct: 260 LSRSVTGEVHHADSGYHVIGMKAVD 284 >3OIG-A nrPDB Length = 266 Score = 81.6 bits (200), Expect = 5e-16, Method: Composition-based stats. Identities = 47/276 (17%), Positives = 90/276 (32%), Gaps = 42/276 (15%) Query: 1 MARTVVLITGCS--SGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPG 58 + +++ G + I +A L ++ YA R K+ L Sbjct: 5 LEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDR-----N 59 Query: 59 SLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 L DV + + + E +V V+ G+ E+ V L+ N G Sbjct: 60 DSIILPCDVTNDAEIETCFASIKE-QVGVI---HGIAHCIAFAN-KEELVGEYLNTNRDG 114 Query: 119 TVR-----------MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLC 167 + +++A P M G ++ +GG + +P +V +K +L+ Sbjct: 115 FLLAHNISSYSLTAVVKAARPMMTE--GGSIVTLTYLGGELVMPNYNVMGVAKASLDASV 172 Query: 168 ESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVF 227 + LA L + ++ I GP+ T + + + D + R Sbjct: 173 KYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRR------------ 220 Query: 228 REAAQNPEEVAE--VFLTALRAPKPTLRYFTTERFL 261 PEEV + FL + + T + Sbjct: 221 ---TTTPEEVGDTAAFLFSDMSRGITGENLHVDSGF 253 >2DKN-A nrPDB Length = 255 Score = 80.8 bits (198), Expect = 8e-16, Method: Composition-based stats. Identities = 60/289 (20%), Positives = 89/289 (30%), Gaps = 69/289 (23%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETL 63 +V+ ITG +SGIG L LA + D++ L+ P G Sbjct: 2 SVIAITGSASGIGAALKELLARAGHTVIGIDRGQADIEA---------DLSTPGGR---- 48 Query: 64 QLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRML 123 +VAA +R G +D LVC AG+G+ L V+ VN G +L Sbjct: 49 ------ETAVAAVLDRCG-GVLDGLVCCAGVGVTAANSGL-------VVAVNYFGVSALL 94 Query: 124 QAFLPDMKRRGSGRVLVTGSVGGLMGLP------------------------FNDV--YC 157 + R ++ GS+ Y Sbjct: 95 DGLAEALSRGQQPAAVIVGSIAATQPGAAELPMVEAMLAGDEARAIELAEQQGQTHLAYA 154 Query: 158 ASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFY 217 SK+A+ L V GV L+++ G V T ++ P + RF Sbjct: 155 GSKYAVTCLARRNVVDWAGRGVRLNVVAPGAVETPLLQASKADP------RYGESTRRFV 208 Query: 218 QYLAHSKQVFREAAQNPEEVAE--VFLTALRAPKPTLRYFTTERFLPLL 264 P EVAE FL +A + + L Sbjct: 209 A--------PLGRGSEPREVAEAIAFLLGPQASFIHGSVLFVDGGMDAL 249 >3UCF-A nrPDB Length = 223 Score = 79.3 bits (194), Expect = 2e-15, Method: Composition-based stats. Identities = 48/262 (18%), Positives = 81/262 (30%), Gaps = 46/262 (17%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 62 +TV ++ G +SGIG LA +L S+ + Sbjct: 6 KTVYVVLGGTSGIGAELAKQLESEHTIVHVASRQTG------------------------ 41 Query: 63 LQLDVRDSKSVAAARERVTEGRVDVLVCNAGL-GLLGPLEALGEDAVASVLDVNVVGTVR 121 LD+ D KSV E + G D L+ AG G + + D G V Sbjct: 42 --LDISDEKSVYHYFETI--GAFDHLIVTAGSYAPAGKVVDVEVTQAKYAFDTKFWGAVL 97 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHL 181 + +K+ G + +T + + V A A+E + LA L P + + Sbjct: 98 AAKHGARYLKQ--GGSITLTSGMLSRKVVANTYVKAAINAAIEATTKVLAKELAP--IRV 153 Query: 182 SLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVF 241 + I G T + + R Y + ++A + Sbjct: 154 NAISPGLTKTEAYKGMNAD-------------DRDAMYQRTQSHLPVGKVGEASDIAMAY 200 Query: 242 LTALRAPKPTLRYFTTERFLPL 263 L A++ T + L Sbjct: 201 LFAIQNSYMTGTVIDVDGGALL 222 >4ALL-A nrPDB Length = 277 Score = 77.3 bits (189), Expect = 7e-15, Method: Composition-based stats. Identities = 40/232 (17%), Positives = 79/232 (34%), Gaps = 15/232 (6%) Query: 1 MARTVVLITGCS--SGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPG 58 + +I G + I +A L ++ Y R K +L E Sbjct: 25 LENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPE---- 80 Query: 59 SLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLL----GPLEALGEDAVASVL 112 Q+DV+ + V E++ + G +D + + + G + Sbjct: 81 -AHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQ 139 Query: 113 DVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAV 172 D++ + M G ++ T +GG + +V +K +LE + LA+ Sbjct: 140 DISSYSLTIVAHEAKKLMPE--GGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLAL 197 Query: 173 LLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSK 224 L P + ++ I GP+ T + V G + + + R + K Sbjct: 198 DLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGK 249 >5I9N-A nrPDB Length = 276 Score = 77.3 bits (189), Expect = 8e-15, Method: Composition-based stats. Identities = 50/270 (18%), Positives = 87/270 (32%), Gaps = 31/270 (11%) Query: 1 MARTVVLITG--CSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPG 58 + +L+TG + I +A + ++ Y R + A G Sbjct: 4 LDGKRILLTGLLSNRSIAYGIAKACKREGAELAFTYVG-------DRFKDRITEFAAEFG 56 Query: 59 SLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLG-----PLEALGEDAVASV 111 S DV D + A + +D LV + G L+ L + Sbjct: 57 SELVFPCDVADDAQIDALFASLKTHWDSLDGLVHSIGFAPREAIAGDFLDGLTRENFRIA 116 Query: 112 LDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLA 171 D++ + +A LP + +L +G +P + +K ALE LA Sbjct: 117 HDISAYSFPALAKAALPMLSDDA--SLLTLSYLGAERAIPNYNTMGLAKAALEASVRYLA 174 Query: 172 VLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAA 231 V L GV ++ I GP+ T L + I +F + ++ + + R Sbjct: 175 VSLGAKGVRVNAISAGPIKT-------------LAASGIKSFGKILDFVESNSPLKRNVT 221 Query: 232 QNPEEVAEVFLTALRAPKPTLRYFTTERFL 261 A FL + A T + Sbjct: 222 IEQVGNAGAFLLSDLASGVTAEVMHVDSGF 251 >5YCX-A nrPDB Length = 266 Score = 75.8 bits (185), Expect = 3e-14, Method: Composition-based stats. Identities = 44/274 (16%), Positives = 85/274 (31%), Gaps = 32/274 (11%) Query: 1 MARTVVLITGCS--SGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPG 58 + ++ G + I +A L + ++ YA R + L + Sbjct: 6 LQGKTFVVMGVANQRSIAWGIARSLHNAGAKLIFTYAGERLERNVRELADTL-----EGQ 60 Query: 59 SLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGL----LGPLEALGEDAVASVL 112 L DV + + + A E + + G + + G D Sbjct: 61 ESLVLPCDVTNDEELTACFETIKQEVGTIHGVAHCIAFANRDDLKGEFVDTSRDGFLLAQ 120 Query: 113 DVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAV 172 +++ + + M G +L +GG + +V +K +LE + LA Sbjct: 121 NISAFSLTAVAREAKKVMTE--GGNILTLTYLGGERVVKNYNVMGVAKASLEASVKYLAN 178 Query: 173 LLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQ 232 L G+ ++ I GP+ T + V + + + R Sbjct: 179 DLGQHGIRVNAISAGPIRTLSAKGVGDFNSILREIEERAPLRRTTTQ------------- 225 Query: 233 NPEEVAE--VFLTALRAPKPTLRYFTTERFLPLL 264 EEV + VFL + A T + +L Sbjct: 226 --EEVGDTAVFLFSDLARGVTGENIHVDSGYHIL 257 >4M89-A nrPDB Length = 261 Score = 75.8 bits (185), Expect = 3e-14, Method: Composition-based stats. Identities = 49/271 (18%), Positives = 92/271 (33%), Gaps = 34/271 (12%) Query: 1 MARTVVLITG--CSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPG 58 + +LITG I +A ++ Y +L E R +A Sbjct: 4 LQGKKILITGMISERSIAYGIAKACREQGAELAFTYVV-------DKLEERVRKMAAELD 56 Query: 59 SLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLG-----PLEALGEDAVASV 111 S + DV + + + +D LV + G L+++ +A + Sbjct: 57 SELVFRCDVASDDEINQVFADLGKHWDGLDGLVHSIGFAPKEALSGDFLDSISREAFNTA 116 Query: 112 LDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLA 171 +++ + +A P M+ R S ++ +G + +P +V +K +LE A Sbjct: 117 HEISAYSLPALAKAARPMMRGRNS-AIVALSYLGAVRAIPNYNVMGMAKASLEAGIRFTA 175 Query: 172 VLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAA 231 L G+ + I GP+ T L + I F + ++A + R Sbjct: 176 ACLGKEGIRCNGISAGPIKT-------------LAASGIADFGKLLGHVAAHNPLRRNVT 222 Query: 232 QNPEEVAE--VFLTALRAPKPTLRYFTTERF 260 EEV FL + + T + Sbjct: 223 I--EEVGNTAAFLLSDLSSGITGEITYVDGG 251 >3SLK-A nrPDB Length = 795 Score = 75.4 bits (184), Expect = 3e-14, Method: Composition-based stats. Identities = 39/178 (21%), Positives = 66/178 (37%), Gaps = 18/178 (10%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 VL+TG + +G +A L + + R E L + Sbjct: 532 TVLVTGGTGALGAEVARHLVIE-RGVRNLVLVSRRGPAASGAAELVAQLTAYGAEVSLQA 590 Query: 65 LDVRDSKSVAAARERV-TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRML 123 DV D +++A + E + +V AG+ G E+L + + VL V G +L Sbjct: 591 CDVADRETLAKVLASIPDEHPLTAVVHAAGVLDDGVSESLTVERLDQVLRPKVDGARNLL 650 Query: 124 QAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGL----------CESLA 171 + PD+ +++ SV G++G Y A+ L+ L SLA Sbjct: 651 ELIDPDV------ALVLFSSVSGVLGSGGQGNYAAANSFLDALAQQRQSRGLPTRSLA 702 >3K2E-A nrPDB Length = 296 Score = 75.4 bits (184), Expect = 3e-14, Method: Composition-based stats. Identities = 36/180 (20%), Positives = 62/180 (34%), Gaps = 15/180 (8%) Query: 18 HLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAAR 77 +A + + ++ Y + + LA G T+ DV D++SV Sbjct: 47 GIAKAVCAQGAEVALTYLS-------ETFKKRVDPLAESLGVKLTVPCDVSDAESVDNMF 99 Query: 78 ERVTE--GRVDVLVCNAGLGLLGPL----EALGEDAVASVLDVNVVGTVRMLQAFLPDMK 131 + + E G +D +V L + + ++ + P M Sbjct: 100 KVLAEEWGSLDFVVHAVAFSDKNELKGRYVDTSLGNFLTSMHISCYSFTYIASKAEPLMT 159 Query: 132 RRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHT 191 G +L G +P +V K ALE + LAV L + ++ I GPV T Sbjct: 160 --NGGSILTLSYYGAEKVVPHYNVMGVCKAALEASVKYLAVDLGKQQIRVNAISAGPVRT 217 >4ZJU-A nrPDB Length = 275 Score = 74.3 bits (181), Expect = 7e-14, Method: Composition-based stats. Identities = 53/275 (19%), Positives = 90/275 (32%), Gaps = 30/275 (10%) Query: 1 MARTVVLITGCSS--GIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPG 58 +A LI G +S I +A L + ++ Y +L + A G Sbjct: 14 LAGKRFLIAGVASKLSIAYGIAQALHREGAELAFTY-------PNEKLKKRVDEFAEQFG 66 Query: 59 SLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGL----LGPLEALGEDA-VASV 111 S DV + A + + VD +V + G G + + Sbjct: 67 SKLVFPCDVAVDAEIDNAFAELAKHWDGVDGVVHSIGFAPAHTLDGDFTDVTDRDGFKIA 126 Query: 112 LDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLA 171 D++ V M +A P ++ R G +L G +P +V +K +LE LA Sbjct: 127 HDISAYSFVAMARAAKPLLQARQ-GCLLTLTYQGSERVMPNYNVMGMAKASLEAGVRYLA 185 Query: 172 VLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAA 231 L G+ ++ I GP+ T L + I +F + + R Sbjct: 186 SSLGVDGIRVNAISAGPIRT-------------LAASGIKSFRKMLDANEKVAPLKRNVT 232 Query: 232 QNPEEVAEVFLTALRAPKPTLRYFTTERFLPLLRM 266 A +FL + A T + + M Sbjct: 233 IEEVGNAALFLCSPWASGITGEILYVDAGFNTVGM 267 >4NR0-A nrPDB Length = 273 Score = 73.9 bits (180), Expect = 1e-13, Method: Composition-based stats. Identities = 56/282 (19%), Positives = 103/282 (36%), Gaps = 33/282 (11%) Query: 1 MARTVVLITGCSS--GIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPG 58 + LI G +S I +A + + ++ + T ++ K +GR+ E A P Sbjct: 4 LTGKRALIVGVASKLSIASGIAAAMHREGAE---LAFTYQNDKLRGRVEEFASGWGSRPE 60 Query: 59 SLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGL----LGPLEALG-EDAVASV 111 DV D + A + + +D++V + G G A+ + Sbjct: 61 LC--FPCDVADDSQIEAVFAALGKHWDGLDIIVHSVGFAPGDQLDGDFTAVTTREGFRIA 118 Query: 112 LDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLA 171 D++ + + +A +M + +G +L +G +P +V +K +LE LA Sbjct: 119 HDISAYSFIALAKAG-REMMKGRNGSLLTLSYLGAERTMPNYNVMGMAKASLEAGVRYLA 177 Query: 172 VLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAA 231 L G ++ + GP+ T L + I +F + A+ +Q Sbjct: 178 GSLGAEGTRVNAVSAGPIRT-------------LAASGIKSFRKML--AANERQTPLRRN 222 Query: 232 QNPEEV--AEVFLTALRAPKPTLRYFTTERFLPLLRM-RLDD 270 EEV A FL + A + + M LDD Sbjct: 223 VTIEEVGNAGAFLCSDLASGISGEILYVDGGFNTTAMGPLDD 264 >2PD3-A nrPDB Length = 275 Score = 72.3 bits (176), Expect = 3e-13, Method: Composition-based stats. Identities = 37/199 (18%), Positives = 69/199 (34%), Gaps = 17/199 (8%) Query: 1 MARTVVLITGCS--SGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPG 58 + LI G + I +A + + Y L + R +A Sbjct: 4 LKGKKGLIVGVANNKSIAYGIAQSCFNQGATLAFTYLN-------ESLEKRVRPIAQELN 56 Query: 59 SLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLE----ALGEDAVASVL 112 S +LDV + + V + G +D +V + LE + A + + Sbjct: 57 SPYVYELDVSKEEHFKSLYNSVKKDLGSLDFIVHSVAFAPKEALEGSLLETSKSAFNTAM 116 Query: 113 DVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAV 172 +++V + + P + VL +G + +V +K ALE LAV Sbjct: 117 EISVYSLIELTNTLKPLL--NNGASVLTLSYLGSTKYMAHYNVMGLAKAALESAVRYLAV 174 Query: 173 LLLPFGVHLSLIECGPVHT 191 L + ++ + GP+ T Sbjct: 175 DLGKHHIRVNALSAGPIRT 193 >5CFZ-A nrPDB Length = 305 Score = 70.4 bits (171), Expect = 9e-13, Method: Composition-based stats. Identities = 54/275 (19%), Positives = 102/275 (37%), Gaps = 31/275 (11%) Query: 1 MARTVVLITGCSS--GIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPG 58 ++ +L+TG +S I +A + + ++ + T ++ K +GR+ E A L G Sbjct: 47 LSGKRILVTGVASKLSIAYGIAQAMHREGAE---LAFTYQNDKLKGRVEEFAAQL----G 99 Query: 59 SLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLE-----ALGEDAVASV 111 S LQ DV + S+ + + + D V + G L+ A+ + Sbjct: 100 SDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIA 159 Query: 112 LDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLA 171 D++ V M +A M GS +L +G +P +V +K +LE +A Sbjct: 160 HDISSYSFVAMAKAC-RSMLNPGS-ALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMA 217 Query: 172 VLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAA 231 + P GV ++ I GP+ T L + I F + + + R Sbjct: 218 NAMGPEGVRVNAISAGPIRT-------------LAASGIKDFRKMLAHCEAVTPIRRTVT 264 Query: 232 QNPEEVAEVFLTALRAPKPTLRYFTTERFLPLLRM 266 + FL + + + + + M Sbjct: 265 IEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAM 299 >4JQC-A nrPDB Length = 282 Score = 70.0 bits (170), Expect = 1e-12, Method: Composition-based stats. Identities = 54/275 (19%), Positives = 102/275 (37%), Gaps = 31/275 (11%) Query: 1 MARTVVLITGCSS--GIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPG 58 ++ +L+TG +S I +A + + ++ + T ++ K +GR+ E A L G Sbjct: 24 LSGKRILVTGVASKLSIAYGIAQAMHREGAE---LAFTYQNDKLKGRVEEFAAQL----G 76 Query: 59 SLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLE-----ALGEDAVASV 111 S LQ DV + S+ + + + D V + G L+ A+ + Sbjct: 77 SDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIA 136 Query: 112 LDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLA 171 D++ V M +A M GS +L +G +P +V +K +LE +A Sbjct: 137 HDISSYSFVAMAKAC-RSMLNPGS-ALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMA 194 Query: 172 VLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAA 231 + P GV ++ I GP+ T L + I F + + + R Sbjct: 195 NAMGPEGVRVNAISAGPIRT-------------LAASGIKDFRKMLAHCEAVTPIRRTVT 241 Query: 232 QNPEEVAEVFLTALRAPKPTLRYFTTERFLPLLRM 266 + FL + + + + + M Sbjct: 242 IEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAM 276 >4NK4-A nrPDB Length = 301 Score = 68.9 bits (167), Expect = 3e-12, Method: Composition-based stats. Identities = 36/207 (17%), Positives = 66/207 (31%), Gaps = 15/207 (7%) Query: 18 HLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAAR 77 +A L S +Q Y + + + LA S + +V D S+ Sbjct: 58 GIAKVLHSAGAQLAFSY-------QGESIGKRLKPLALTVDSDFMIPCNVEDPSSMDLLF 110 Query: 78 ERVTE--GRVDVLVCNAGLGLL----GPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMK 131 ER+ E +D +V + GP D + V+ +++ M Sbjct: 111 ERIKERWETLDFVVHSIAFSDKNELRGPYYNTSRDNFIQTMLVSCFSFTEIVRRAAQLMP 170 Query: 132 RRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHT 191 G ++ G + +P + +K ALE + LA + ++ I GPV T Sbjct: 171 H--GGAMITLTYGGSMRVVPNYNAMAPAKSALESSTKYLACDYGGMNIRINAISAGPVRT 228 Query: 192 AFMEKVLGSPEEVLDRTDIHTFHRFYQ 218 + + + R Sbjct: 229 LAGASISNGRDIAAWSKENSPLKRTVS 255 >1FJH-A nrPDB Length = 257 Score = 68.5 bits (166), Expect = 4e-12, Method: Composition-based stats. Identities = 55/266 (20%), Positives = 83/266 (31%), Gaps = 69/266 (25%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETL 63 ++++I+GC++GIG L + Q + R E L+ G + + Sbjct: 2 SIIVISGCATGIGAATRKVLEAAGHQIVGIDI---------RDAEVIADLSTAEGRKQAI 52 Query: 64 QLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRML 123 DV S +D LV AGLG + +V+ VN G ++ Sbjct: 53 -ADVLAKCS----------KGMDGLVLCAGLGPQTKVL-------GNVVSVNYFGATELM 94 Query: 124 QAFLPDMKRRGSGRVLVTGSVGGLM----------------------------GLPFNDV 155 AFLP +K+ +V SV N Sbjct: 95 DAFLPALKKGHQPAAVVISSVASAHLAFDKNPLALALEAGEEAKARAIVEHAGEQGGNLA 154 Query: 156 YCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHR 215 Y SK AL A GV L+ I G T ++ L P R Sbjct: 155 YAGSKNALTVAVRKRAAAWGEAGVRLNTIAPGATETPLLQAGLQDP-------------R 201 Query: 216 FYQYLAHSKQVFREAAQNPEEVAEVF 241 + + +A P E+A V Sbjct: 202 YGESIAKFVP-PMGRRAEPSEMASVI 226 >4J3F-A nrPDB Length = 280 Score = 68.1 bits (165), Expect = 6e-12, Method: Composition-based stats. Identities = 38/275 (13%), Positives = 86/275 (31%), Gaps = 31/275 (11%) Query: 1 MARTVVLITG--CSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPG 58 +A +LITG + I +A + + ++ Y G+ + L Sbjct: 24 LAGKKILITGLLSNKSIAYGIAKAMHREGAELAFTYV--------GQFKDRVEKLCAEFN 75 Query: 59 SLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLL-----GPLEALGEDAVASV 111 L DV + + + + +D +V + ++ + + + Sbjct: 76 PAAVLPCDVISDQEIKDLFVELGKVWDGLDAIVHSIAFAPRDQLEGNFIDCVTREGFSIA 135 Query: 112 LDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLA 171 D++ + + M + + ++ +G +P + +K +LE A Sbjct: 136 HDISAYSFAALAKEG-RSMMKNRNASMVALTYIGAEKAMPSYNTMGVAKASLEATVRYTA 194 Query: 172 VLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAA 231 + L G+ ++ + GP+ T L + I F + Y A + + Sbjct: 195 LALGEDGIKVNAVSAGPIKT-------------LAASGISNFKKMLDYNAMVSPLKKNVD 241 Query: 232 QNPEEVAEVFLTALRAPKPTLRYFTTERFLPLLRM 266 FL + A T + + M Sbjct: 242 IMEVGNTVAFLCSDMATGITGEVVHVDAGYHCVSM 276 >4Q9N-A nrPDB Length = 298 Score = 65.0 bits (157), Expect = 4e-11, Method: Composition-based stats. Identities = 45/294 (15%), Positives = 80/294 (27%), Gaps = 49/294 (16%) Query: 1 MARTVVLITGCSS--GIGLHLAVRLASDPSQ--------SFKVYATLRDLKTQGRLWEAA 50 + + I G G G +A LA + +K+++ +L E + Sbjct: 6 LTGKIAFIAGIGDDNGYGWGIAKMLAEAGATILVGTWVPIYKIFSQSLELGKFNASRELS 65 Query: 51 RALACPPGSLETLQLDVRDSKS------------------VAAARERVT--EGRVDVLVC 90 + + + V+ E+V G +D+LV Sbjct: 66 NGELLTFAKIYPMDASFDTPEDIPQEILENKRYKDLSGYTVSEVVEQVKKHFGHIDILVH 125 Query: 91 NAGLGL--LGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLM 148 + PL + L + + +L F P M + + + Sbjct: 126 SLANSPEIAKPLLDTSRKGYLAALSTSSYSFISLLSHFGPIM--NAGASTISLTYLASMR 183 Query: 149 GLPFN-DVYCASKFALEGLCESLAVLLLPF-GVHLSLIECGPVHTAFMEKVLGSPEEVLD 206 +P A+K ALE + LA GV ++ I GP+ + Sbjct: 184 AVPGYGGGMNAAKAALESDTKVLAWEAGRRWGVRVNTISAGPLAS-------------RA 230 Query: 207 RTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVFLTALRAPKPTLRYFTTERF 260 I R Y + A FL + A T + Sbjct: 231 GKAIGFIERMVDYYQDWAPLPSPMEAEQVGAAAAFLVSPLASAITGETLYVDHG 284 >1ENP-A nrPDB Length = 312 Score = 63.1 bits (152), Expect = 2e-10, Method: Composition-based stats. Identities = 55/306 (17%), Positives = 94/306 (30%), Gaps = 51/306 (16%) Query: 1 MARTVVLITGCSS--GIGLHLAVRLASDPSQSFKVYATLR----------------DLKT 42 + I G + G G +A LA+ ++ + Sbjct: 16 LRGKRAFIAGIADDNGYGWAVAKSLAAAGAEILVGTWVPALNIFETSLRRGKFDQSRVLP 75 Query: 43 QGRLWEAARA--LACPPGSLETLQLDVRDSKS--------VAAARE--RVTEGRVDVLVC 90 G L E + L + E + DV+ +K V A E R G +D+LV Sbjct: 76 DGSLMEIKKVYPLDAVFDNPEDVPEDVKANKRYAGSSNWTVQEAAECVRQDFGSIDILVH 135 Query: 91 ---NAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGL 147 N G + PL + + + V +L FLP M G + + Sbjct: 136 SLAN-GPEVSKPLLETSRKGYLAAISASSYSFVSLLSHFLPIM--NPGGASISLTYIASE 192 Query: 148 MGLPFNDV-YCASKFALEGLCESLAVLLLPF-GVHLSLIECGPVHTAFMEKVLGSPEEVL 205 +P ++K ALE LA + ++ I GP+ + Sbjct: 193 RIIPGYGGGMSSAKAALESDTRVLAFEAGRKQNIRVNTISAGPLGS-------------R 239 Query: 206 DRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVFLTALRAPKPTLRYFTTERFLPLLR 265 I +Y ++ + + + A FL + A T + L + Sbjct: 240 AAKAIGFIDTMIEYSYNNAPIQKTLTADEVGNAAAFLVSPLASAITGATIYVDNGLNSMG 299 Query: 266 MRLDDP 271 + LD P Sbjct: 300 VALDSP 305 >2O2S-A nrPDB Length = 315 Score = 62.7 bits (151), Expect = 2e-10, Method: Composition-based stats. Identities = 55/309 (17%), Positives = 103/309 (33%), Gaps = 49/309 (15%) Query: 1 MARTVVLITGCSS--GIGLHLAVRLASDPSQSFK-----VYATLRDLKTQGRLWEAARA- 52 + + G + G G +A LAS ++ V + GRL E + Sbjct: 7 LRGQTAFVAGVADSHGYGWAIAKHLASAGARVALGTWPPVLGLFQKSLQSGRLDEDRKLP 66 Query: 53 ------------LACPPGSLETLQLDVRDSKSVA----------AARERVTEGRVDVLVC 90 L E + D++D+K A A + + G +D+LV Sbjct: 67 DGSLIEFAGVYPLDAAFDKPEDVPQDIKDNKRYAGVDGYTIKEVAVKVKQDLGNIDILVH 126 Query: 91 ---NAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGL 147 N G + PL + + V +LQ F P M G + + Sbjct: 127 SLAN-GPEVTKPLLETSRKGYLAASSNSAYSFVSLLQHFGPIMNE--GGSAVTLSYLAAE 183 Query: 148 MGLPFN-DVYCASKFALEGLCESLAVLLL-PFGVHLSLIECGPVHTAFMEKVLGSPEEVL 205 +P ++K ALE +LA +GV ++ I GP+ + + Sbjct: 184 RVVPGYGGGMSSAKAALESDTRTLAWEAGQKYGVRVNAISAGPLKS--------RAASAI 235 Query: 206 DRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV--AEVFLTALRAPKPTLRYFTTERFLPL 263 ++ +F + +++ + ++V A +FL + A + + L Sbjct: 236 GKSGEKSFIDYAIDYSYNNA-PLRRDLHSDDVGGAALFLLSPLARAVSGVTLYVDNGLHA 294 Query: 264 LRMRLDDPS 272 + +D S Sbjct: 295 MGQAVDSRS 303 >2NTV-A nrPDB Length = 268 Score = 61.5 bits (148), Expect = 4e-10, Method: Composition-based stats. Identities = 50/277 (18%), Positives = 93/277 (33%), Gaps = 35/277 (12%) Query: 1 MARTVVLITG--CSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPG 58 + +L++G S I H+A +Q L RL R P Sbjct: 4 LEGKRILVSGIITDSSIAFHIAKVAQEAGAQLV--------LTGFDRLRLIQRIADRLPD 55 Query: 59 SLETLQLDVRDSKSVAAARERVT----EG-RVDVLVCNAGLGL-----LGPLEALGEDAV 108 ++LDV++ + +A ERVT EG ++D +V + G + V Sbjct: 56 KAPLIELDVQNEEHLATLAERVTAEIGEGNKLDGVVHSIGFMPQTGMGTNQFFDAPYEDV 115 Query: 109 ASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVY---CASKFALEG 165 + + ++ + +A L M G ++ Y +K ALE Sbjct: 116 SKGIHISTYSYASLAKALLLIM--NSGGSIVGM----DFDPTRAMPAYNWMTVAKSALES 169 Query: 166 LCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQ 225 + +A +GV +L+ GP+ T M ++G + + + + Sbjct: 170 VNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGG----AFGEEAGAQMQLLEEGWDQRA 225 Query: 226 VFREAAQNPEEVAEVF--LTALRAPKPTLRYFTTERF 260 ++P VA+ L + P T + Sbjct: 226 PIGWNMKDPTPVAKTVCALLSEWLPATTGSIIYADGG 262 >4OYR-A nrPDB Length = 289 Score = 61.2 bits (147), Expect = 6e-10, Method: Composition-based stats. Identities = 51/269 (18%), Positives = 90/269 (33%), Gaps = 35/269 (13%) Query: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLD 66 +IT S I H+A +Q L RL R P L+LD Sbjct: 35 IITDSS--IAFHIARVAQEQGAQLV--------LTGFDRLRLIQRITDRLPAKAPLLELD 84 Query: 67 VRDSKSVAAARERVTEG-----RVDVLVCNAGLGL-----LGPLEALGEDAVASVLDVNV 116 V++ + +A+ RVTE ++D +V + G + P V+ + ++ Sbjct: 85 VQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISA 144 Query: 117 VGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVY---CASKFALEGLCESLAVL 173 M +A LP M G ++ Y +K ALE + +A Sbjct: 145 YSYASMAKALLPIM--NPGGSIVGM----DFDPSRAMPAYNWMTVAKSALESVNRFVARE 198 Query: 174 LLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQN 233 +GV +L+ GP+ T M ++G + + + + ++ Sbjct: 199 AGKYGVRSNLVAAGPIRTLAMSAIVGG----ALGEEAGAQIQLLEEGWDQRAPIGWNMKD 254 Query: 234 PEEVAEVF--LTALRAPKPTLRYFTTERF 260 VA+ L + P T + Sbjct: 255 ATPVAKTVCALLSDWLPATTGDIIYADGG 283 >1I3M-A nrPDB Length = 348 Score = 58.9 bits (141), Expect = 3e-09, Method: Composition-based stats. Identities = 41/184 (22%), Positives = 68/184 (36%), Gaps = 27/184 (14%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARAL-ACPPGS 59 MA V L+TG + IG H + L + + G L E+ R + S Sbjct: 1 MAEKV-LVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRS 59 Query: 60 LETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGT 119 +E ++D+ D ++ ++ + V + AGL +G D VN+ GT Sbjct: 60 VEFEEMDILDQGALQRLFKKYSFMAV---IHFAGLKAMGESVQKPLDYYR----VNLTGT 112 Query: 120 VRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFN-------------DVYCASKFALEGL 166 + L MK G ++ + S + G P + Y SKF +E + Sbjct: 113 I----QLLEIMKAHGVKNLVFSSS-ATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEM 167 Query: 167 CESL 170 L Sbjct: 168 IRDL 171 >4LIS-A nrPDB Length = 371 Score = 55.8 bits (133), Expect = 2e-08, Method: Composition-based stats. Identities = 35/174 (20%), Positives = 53/174 (30%), Gaps = 30/174 (17%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 VL+TG + IG + L + E E QL Sbjct: 6 VLVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELI-----SGKKAEFAQL 60 Query: 66 DVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQA 125 DV D + E + +D ++ A L +G D VNV GT+ Sbjct: 61 DVTDEAAFDKVFEAHPD--IDSVIHFAALKAVGESGEKPLDYYH----VNVYGTI----C 110 Query: 126 FLPDMKRRGSGRVLVTGS---------------VGGLMGLPFNDVYCASKFALE 164 L M R ++ + S + L + Y +KFA+E Sbjct: 111 LLRSMVRHNVTNIVFSSSATVYGDATRFPDMIPIPEHCPLGPTNPYGNTKFAIE 164 >3F4B-A nrPDB Length = 323 Score = 51.9 bits (123), Expect = 3e-07, Method: Composition-based stats. Identities = 32/198 (16%), Positives = 64/198 (32%), Gaps = 17/198 (8%) Query: 81 TEGRVDVLVC---NAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGR 137 G++ +LV N G + L D + + + + + F M G Sbjct: 117 KYGKISMLVHSLAN-GREVQKSLLDTSRDGYLDAISKSSYSLISLCKHFCKFM--NSGGS 173 Query: 138 VLVTGSVGGLMGLPFNDV-YCASKFALEGLCESLAVLLL-PFGVHLSLIECGPVHTAFME 195 V+ +P ++K ALE LA L + + ++ I GP+ + Sbjct: 174 VVSLTYQASQKVVPGYGGGMSSAKAALESDTRVLAYYLGRKYNIRINTISAGPLKSRAAT 233 Query: 196 KVLGSPEEVLD------RTDIHTFHRFYQYLAHS-KQVFREAAQNPEEVAEV--FLTALR 246 + + TD + + +S K + +V V FL + Sbjct: 234 AINKFNNNQKNNMNSSGETDKQNYSFIDYAIDYSEKYAPLKKKLLSTDVGSVASFLLSKE 293 Query: 247 APKPTLRYFTTERFLPLL 264 + T + + L ++ Sbjct: 294 SSAVTGQTIYVDNGLNIM 311 >3RFT-A nrPDB Length = 267 Score = 51.9 bits (123), Expect = 3e-07, Method: Composition-based stats. Identities = 35/180 (19%), Positives = 58/180 (32%), Gaps = 36/180 (20%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 MA +L+TG + +G + RLA A L L G E Sbjct: 1 MAMKRLLVTGAAGQLGRVMRERLAPM--AEILRLADLSPLDPAGPNEE------------ 46 Query: 61 ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 +Q D+ D+ +V A D +V G+ + P +L N++G Sbjct: 47 -CVQCDLADANAVNAMVA-----GCDGIVHLGGISVEKP--------FEQILQGNIIGLY 92 Query: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLP----FNDVYCASKFALEGLCESLAVLLLP 176 + +A + G R++ S + P A L G+ + L Sbjct: 93 NLYEAA----RAHGQPRIVFASSNHTIGYYPQTERLGPDVPARPDGLYGVSKCFGENLAR 148 >1UDA-A nrPDB Length = 338 Score = 49.6 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 31/167 (18%), Positives = 57/167 (34%), Gaps = 28/167 (16%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 VL+TG S IG H V+L + + ++ + E ++ Sbjct: 3 VLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVIERLG-----GKHPTFVEG 57 Query: 66 DVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQA 125 D+R+ + E + + +D ++ AGL +G + + NV GT+R++ A Sbjct: 58 DIRNEALMT---EILHDHAIDTVIHFAGLKAVGESVQKPLEYYDN----NVNGTLRLISA 110 Query: 126 FLPDMKRRGSGRVLVTGSVGGLMGLPF------------NDVYCASK 160 M+ + + S P Y SK Sbjct: 111 ----MRAANVKNFIFSSSATVYGDNPKIPYVESFPTGTPQSPYGKSK 153 >2GN9-A nrPDB Length = 344 Score = 49.6 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 30/161 (18%), Positives = 60/161 (37%), Gaps = 24/161 (14%) Query: 1 MARTVVLITGCSSGIGLHLAVR-LASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGS 59 + +LITG + G + L + ++ VY ++ L ++ A+ Sbjct: 19 LDNQTILITGGTGSFGKCFVRKVLDTTNAKKIIVY-------SRDELKQSEMAMEFNDPR 71 Query: 60 LETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGT 119 + DVRD + + A E VD+ + A L + P+ + N++G Sbjct: 72 MRFFIGDVRDLERLNYALE-----GVDICIHAAALKHV-PIAEYNP---LECIKTNIMGA 122 Query: 120 VRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASK 160 ++ A L + + V+ P ++Y A+K Sbjct: 123 SNVINACLKNAISQ----VIALS--TDKAANP-INLYGATK 156 >2PTG-A nrPDB Length = 319 Score = 49.2 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 58/322 (18%), Positives = 94/322 (29%), Gaps = 62/322 (19%) Query: 1 MARTVVLITGC--SSGIGLHLAVRLASDPSQSFK-----------------------VYA 35 + + G S+G G + L + ++ YA Sbjct: 7 LRGKTAFVAGVADSNGYGWAICKLLRAAGARVLVGTWPPVYSIFKKGLESSRFEQDSFYA 66 Query: 36 TLRDLKTQGRLWEAARALACPPGSLETLQLD--------VRDSK----------SVAAAR 77 K E L D V +K S A Sbjct: 67 QEPSSKVAAEAAEKPVDLVFDKIYPLDAVFDTPQDVPPEVSSNKRYAGVGGFTISEVAEA 126 Query: 78 ERVTEGRVDVLVC---NAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRG 134 R G++D+LV N G + PL + + + V +LQ FLP MK Sbjct: 127 VRADVGQIDILVHSLAN-GPEVTKPLLQTSRKGYLAAVSSSSYSFVSLLQHFLPLMKE-- 183 Query: 135 SGRVLVTGSVGGLMGLPFNDV-YCASKFALEGLCESLAVLLLP-FGVHLSLIECGPVHTA 192 G L + +P ++K ALE C +LA V ++ I GP+ + Sbjct: 184 GGSALALSYIASEKVIPGYGGGMSSAKAALESDCRTLAFEAGRARAVRVNCISAGPLKS- 242 Query: 193 FMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV--AEVFLTALRAPKP 250 + + TF + + + ++V A +FL + A Sbjct: 243 -------RAASAIGKAGDKTFIDLAIDYSEANA-PLQKELESDDVGRAALFLLSPLARAV 294 Query: 251 TLRYFTTERFLPLLRMRLDDPS 272 T + L + LD S Sbjct: 295 TGATLYVDNGLHAMGQALDSKS 316 >1OOE-A nrPDB Length = 236 Score = 48.5 bits (114), Expect = 4e-06, Method: Composition-based stats. Identities = 36/249 (14%), Positives = 74/249 (29%), Gaps = 24/249 (9%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 M+ V++ G +G + + + + D L + + S+ Sbjct: 1 MSSGKVIVYGGKGALGSAILEFFKKNGYTVLNIDLSANDQADSNILVDGNKNWTEQEQSI 60 Query: 61 ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGE-DAVASVLDVNVVGT 119 + + +VD + C AG G + ++ +V + Sbjct: 61 ------------LEQTASSLQGSQVDGVFCVAGGWAGGSASSKDFVKNADLMIKQSVWSS 108 Query: 120 VRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL-AVLLL-PF 177 + +K G + +TG+ + P Y +K A+ L SL A P Sbjct: 109 AIAAKLATTHLK--PGGLLQLTGAAAAMGPTPSMIGYGMAKAAVHHLTSSLAAKDSGLPD 166 Query: 178 GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEV 237 + I + T K + + D ++ H + E + P Sbjct: 167 NSAVLTIMPVTLDTPMNRKWMPN-------ADHSSWTPLSFISEHLLKWTTETSSRPSSG 219 Query: 238 AEVFLTALR 246 A + +T Sbjct: 220 ALLKITTEN 228 >4R1T-A nrPDB Length = 337 Score = 48.5 bits (114), Expect = 4e-06, Method: Composition-based stats. Identities = 50/283 (17%), Positives = 82/283 (28%), Gaps = 57/283 (20%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 ++ VV +TG I L L D K R L L Sbjct: 8 VSGQVVCVTGAGGFIASWLVKILLEKGYTVRGTVRNPDDPKNG-----HLRELEGAKERL 62 Query: 61 ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 + D+ D +S+ A D + A P + + V+GT Sbjct: 63 TLCKADLLDYQSLREAIN-----GCDGVFHTASPVTDDPEQMVEPA---------VIGTK 108 Query: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDV---------------------YCAS 159 ++ A R RV+ T S+G + P D YC Sbjct: 109 NVINAAAEANVR----RVVFTSSIGAVYMDPNRDPETVVDETCWSDPDFCKNTKNWYCYG 164 Query: 160 KFALEGLCESLAVLLLP-FGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQ 218 K + E A GV L +I V ++ + + ++ Sbjct: 165 KM----VAEQAAWEEAKEKGVDLVVINPVLVQGPLLQTTVN--------ASVLHILKYLT 212 Query: 219 YLAHSKQVFREAAQNPEEVAEVFLTALRAPKPTLRYFTTERFL 261 A + +A + ++VA + P+ + RY E L Sbjct: 213 GSAKTYANSVQAYVDVKDVALAHILLYETPEASGRYLCAESVL 255 >3ORF-A nrPDB Length = 251 Score = 47.3 bits (111), Expect = 9e-06, Method: Composition-based stats. Identities = 34/205 (16%), Positives = 62/205 (30%), Gaps = 26/205 (12%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 M++ + L+ G S +G + S + + P Sbjct: 21 MSKNI-LVLGGSGALGAEVVKFFKSKSWNTISI-----------------DFRENPNADH 62 Query: 61 ETLQLDVRDSKSVAAARERVTEG--RVDVLVCNAGLGLLG-PLEALGEDAVASVLDVNVV 117 D + + + E++ +VD VC AG G +V ++D+N+ Sbjct: 63 SFTIKD-SGEEEIKSVIEKINSKSIKVDTFVCAAGGWSGGNASSDEFLKSVKGMIDMNLY 121 Query: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLL-- 175 + G ++TG+ L Y A+K A + + LA Sbjct: 122 SAFASAHIGAKLL--NQGGLFVLTGASAALNRTSGMIAYGATKAATHHIIKDLASENGGL 179 Query: 176 PFGVHLSLIECGPVHTAFMEKVLGS 200 P G I + T K + Sbjct: 180 PAGSTSLGILPVTLDTPTNRKYMSD 204 >2O2Y-A nrPDB Length = 349 Score = 45.8 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 33/229 (14%), Positives = 74/229 (32%), Gaps = 39/229 (17%) Query: 71 KSVAAARERVTEGRVDVLVC---NAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFL 127 + VA + G++++LV NA + L L + + + + F+ Sbjct: 113 EDVANLIHQ-KYGKINMLVHSLANA-KEVQKDLLNTSRKGYLDALSKSSYSLISLCKYFV 170 Query: 128 PDMKRRGSGRVLVTGSVGGLMGLPFNDV-YCASKFALEGLCESLAVLLLP-FGVHLSLIE 185 MK + ++ +P ++K ALE LA L + + ++ I Sbjct: 171 NIMKPQS--SIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLGRNYNIRINTIS 228 Query: 186 CGPVH----TAFME---------------------KVLGSPEEVLDRTDIHTFHRFYQYL 220 GP+ TA + ++ + E ++ + + + + Sbjct: 229 AGPLKSRAATAINKLNNTYENNTNQNKNRNSHDVHNIMNNSGEKEEKKNSASQNYTFIDY 288 Query: 221 AH---SKQVFREAAQNPEEVAEV--FLTALRAPKPTLRYFTTERFLPLL 264 A K ++ V FL + + T + + L ++ Sbjct: 289 AIEYSEKYAPLRQKLLSTDIGSVASFLLSRESRAITGQTIYVDNGLNIM 337 >1GY8-A nrPDB Length = 397 Score = 45.4 bits (106), Expect = 4e-05, Method: Composition-based stats. Identities = 35/167 (20%), Positives = 57/167 (34%), Gaps = 27/167 (16%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ- 64 VL+ G + IG H L D + S + +L + E +A + + Sbjct: 5 VLVCGGAGYIGSHFVRALLRDTNHSVVIVDSLVGTHGKSDHVETRENVARKLQQSDGPKP 64 Query: 65 -----------LDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVA--SV 111 DVR+ + R G +D +V + A+GE Sbjct: 65 PWADRYAALEVGDVRNEDFLNGVFTR--HGPIDAVV------HMCAFLAVGESVRDPLKY 116 Query: 112 LDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCA 158 D NVVG +R+LQA M +++ + S + G P Sbjct: 117 YDNNVVGILRLLQA----MLLHKCDKIIFSSS-AAIFGNPTMGSVST 158 >1R66-A nrPDB Length = 337 Score = 43.8 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 37/181 (20%), Positives = 55/181 (30%), Gaps = 38/181 (20%) Query: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLD 66 L+TG + IG H +L + + A A L + D Sbjct: 4 LVTGGAGFIGSHFVRQLLAGAYPDVPADEVIVLDSLTYAGNRANLAPVDADPRLRFVHGD 63 Query: 67 VRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVL-------DVNVVGT 119 +RD+ +A VD +V A E V + + NV GT Sbjct: 64 IRDAGLLARELR-----GVDAIVHFAA-----------ESHVDRSIAGASVFTETNVQGT 107 Query: 120 VRMLQAFLPDMKRRGSGRVLVTG-----------SVGGLMGLPFNDVYCASKFALEGLCE 168 +LQ + G GRV+ S L N Y ASK + + Sbjct: 108 QTLLQCAVDA----GVGRVVHVSTDEVYGSIDSGSWTESSPLEPNSPYAASKAGSDLVAR 163 Query: 169 S 169 + Sbjct: 164 A 164 >1Z45-A nrPDB Length = 699 Score = 43.1 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 26/142 (18%), Positives = 50/142 (35%), Gaps = 16/142 (11%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 +VL+TG + IG H V L + E P Sbjct: 10 TSKIVLVTGGAGYIGSHTVVELIENGYDCVVADNLSNSTYDSVARLEVLTKHHIP----- 64 Query: 62 TLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 ++D+ D K + + ++D ++ AGL +G + + N++GTV Sbjct: 65 FYEVDLCDRKGLEKVFKEY---KIDSVIHFAGLKAVGESTQIPLRYYHN----NILGTVV 117 Query: 122 MLQAFLPDMKRRGSGRVLVTGS 143 + L M++ + + + S Sbjct: 118 L----LELMQQYNVSKFVFSSS 135 >3ENK-A nrPDB Length = 341 Score = 42.7 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 28/154 (18%), Positives = 54/154 (35%), Gaps = 17/154 (11%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 + +L+TG + IG H AV L + + D + AR + Sbjct: 4 TKGTILVTGGAGYIGSHTAVELLAHGYDVV-----IADNLVNSKREAIARIEKITGKTPA 58 Query: 62 TLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 + DV D +++A + + + A L +G A + + + Sbjct: 59 FHETDVSDERALARIFDA---HPITAAIHFAALKAVGESVAKPIEYYRN--------NLD 107 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDV 155 L + L M+ R R++ + S + G+P Sbjct: 108 SLLSLLRVMRERAVKRIVFSSS-ATVYGVPERSP 140 >1DIR-A nrPDB Length = 241 Score = 41.9 bits (97), Expect = 4e-04, Method: Composition-based stats. Identities = 36/204 (17%), Positives = 66/204 (32%), Gaps = 26/204 (12%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 AR V L+ G +G + + EA+ ++ Sbjct: 7 ARRV-LVYGGRGALGSRCVQAFRARNWWVASIDVV--------ENEEASASVIVKMTDSF 57 Query: 62 TLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDA-----VASVLDVNV 116 T Q D + A + + + +VD ++C AG G ++ + + Sbjct: 58 TEQAD----QVTAEVGKLLGDQKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSIWTST 113 Query: 117 VGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLA--VLL 174 + +K G + + G+ L G P Y +K A+ LC+SLA Sbjct: 114 IS----SHLATKHLKE--GGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKNSG 167 Query: 175 LPFGVHLSLIECGPVHTAFMEKVL 198 +P G + + T K + Sbjct: 168 MPSGAAAIAVLPVTLDTPMNRKSM 191 >4G5H-A nrPDB Length = 363 Score = 41.1 bits (95), Expect = 7e-04, Method: Composition-based stats. Identities = 31/124 (25%), Positives = 51/124 (41%), Gaps = 16/124 (12%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETL 63 ++LITG + G + R + +++ RD K Q + + L+ Sbjct: 26 KILLITGGTGSFGNAVMKRFLDSNIKEIRIF--SRDEKKQDDIRK-----KYNNSKLKFY 78 Query: 64 QLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRML 123 DVRDS+SV A VD + A L + E +AV N++GT +L Sbjct: 79 IGDVRDSQSVETAMRD-----VDYVFHAAALKQVPSCEFFPVEAVK----TNIIGTENVL 129 Query: 124 QAFL 127 Q+ + Sbjct: 130 QSAI 133 >2NNL-D nrPDB Length = 337 Score = 40.4 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 43/282 (15%), Positives = 83/282 (29%), Gaps = 45/282 (15%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 V +TG S IG L +RL ++K L + +A L + Sbjct: 7 TVCVTGASGFIGSWLVMRLLERGYTVRATVRDPTNVKKVKHLLDLPKAETH----LTLWK 62 Query: 65 LDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDA-VASVLDVNVVGTVRML 123 D+ D S A + T G+ + V+ + G + ++ Sbjct: 63 ADLADEGSFDEAIKGCT-----------GVFHVATPMDFESKDPENEVIKPTIEGMLGIM 111 Query: 124 QAFLPDMKRRGSGRVLVTGSVGGLMGLPFN-DVY----------CASK---FALEGLCES 169 ++ R R++ T S G + VY C +K + + ++ Sbjct: 112 KSCAAAKTVR---RLVFTSSAGTVNIQEHQLPVYDESCWSDMEFCRAKKMTAWMYFVSKT 168 Query: 170 LAVLLL-----PFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSK 224 LA + I V F+ + + I AH Sbjct: 169 LAEQAAWKYAKENNIDFITIIPTLVVGPFIMS-------SMPPSLITALSPITGNEAHYS 221 Query: 225 QVFREAAQNPEEVAEVFLTALRAPKPTLRYFTTERFLPLLRM 266 + + + +++ + PK RY + +L + Sbjct: 222 IIRQGQFVHLDDLCNAHIYLFENPKAEGRYICSSHDCIILDL 263 >5GUP-L nrPDB Length = 377 Score = 40.0 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 38/264 (14%), Positives = 75/264 (28%), Gaps = 58/264 (21%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 ++ V + G + +G ++ L SQ Y R G + Sbjct: 51 VSGIVATVFGATGFLGRYVVNHLGRMGSQVIVPYRCEPYDTMHLRPM-------GDLGQI 103 Query: 61 ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 ++ + +D S+ E N + L+G V V Sbjct: 104 IFMEWNGKDKDSIRKVVEH----------SNVVINLVGREWETKNFDFEDVF-------V 146 Query: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180 ++ A K G +++ + + P Y SK + V Sbjct: 147 KIPHAIAQVSKEAGVEKLIHISHLNADIKSP--SRYLRSKA------------VGEKEVR 192 Query: 181 LSLIECGPVHTAFMEKVLGSPEEVLDRTDI-----HTFHRFYQYLAHSKQVFREAAQNP- 234 AF E + P ++ R D + F + +E + P Sbjct: 193 A----------AFPEATIIKPSDIFGREDRFLNYFASMRWFGGVP--LISLGKETVKQPV 240 Query: 235 --EEVAEVFLTALRAPKPTLRYFT 256 +V++ + A++ P + F Sbjct: 241 YIVDVSKGIINAIKDPDAKGKTFA 264 >1VL0-A nrPDB Length = 292 Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 24/178 (13%), Positives = 49/178 (27%), Gaps = 54/178 (30%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 +LITG + +G + +L ++E + Sbjct: 15 ILITGANGQLGREIQKQL--------------------------------KGKNVEVIPT 42 Query: 66 DVRDSK--SVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRML 123 DV+D +V A + E + +V++ A E+ +N +G + Sbjct: 43 DVQDLDITNVLAVNKFFNEKKPNVVINCAAHT----AVDKCEEQYDLAYKINAIGPKNLA 98 Query: 124 QAFLPDMKRRGSGRVLVTGSVGGLMGLPF-----------NDVYCASKFALEGLCESL 170 A ++ + G Y +K E ++L Sbjct: 99 AAAYSV-----GAEIVQISTDYVFDGEAKEPITEFDEVNPQSAYGKTKLEGENFVKAL 151 >4J2O-A nrPDB Length = 363 Score = 39.2 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 25/132 (18%), Positives = 46/132 (34%), Gaps = 20/132 (15%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETL 63 V+LITG + G + R + ++++ + R + L G Sbjct: 24 KVLLITGGTGSFGNAVLKRFLETDIKEIRIFSRDEKKQDDMRKKYHSAKLKFYIG----- 78 Query: 64 QLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVA--SVLDVNVVGTVR 121 DVRD S+ A V + L+ + + NV+GT Sbjct: 79 --DVRDYNSILNATRGVDY-----------IYHAAALKQVPSCEFHPMEAVKTNVLGTEN 125 Query: 122 MLQAFLPDMKRR 133 +L+A + + +R Sbjct: 126 VLEAAIQNHVKR 137 >6G2J-P nrPDB Length = 377 Score = 39.2 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 26/142 (18%), Positives = 41/142 (28%), Gaps = 24/142 (16%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 ++ V + G + +G ++ L SQ Y RL G L Sbjct: 51 VSGVVATVFGATGFLGRYVVNHLGRMGSQVIIPYRCDVYDIMHLRLM-------GDLGQL 103 Query: 61 ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120 L+ D RD S+ A + N + L+G V V Sbjct: 104 TFLEWDARDKDSIRKAVQH----------SNVVINLIGREWETRNFDFEDVF-------V 146 Query: 121 RMLQAFLPDMKRRGSGRVLVTG 142 + +A K G R + Sbjct: 147 NIPRAIAQASKEAGVERFIHVS 168 >2Q1W-A nrPDB Length = 333 Score = 39.2 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 41/197 (20%), Positives = 59/197 (29%), Gaps = 48/197 (24%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 V ITG IG H+A L + + D GR R +L ++ Sbjct: 24 VFITGICGQIGSHIAELLLERGDKVVGI-----DNFATGR-----REHLKDHPNLTFVEG 73 Query: 66 DVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAV-ASVLDVNVVGTVRMLQ 124 + D V + D +V A D L N VG ++Q Sbjct: 74 SIADHALVNQLIGDLQP---DAVVHTAASYKD-------PDDWYNDTL-TNCVGGSNVVQ 122 Query: 125 AFLPDMKRRGSGRVLV--TGSVGGLMG-----------LPFNDVYCASK---------FA 162 A K+ GR + T G+ P N Y SK Sbjct: 123 AA----KKNNVGRFVYFQTALCYGVKPIQQPVRLDHPRNPANSSYAISKSANEDYLEYSG 178 Query: 163 LEGLCESLAVLLLPFGV 179 L+ + LA ++ P V Sbjct: 179 LDFVTFRLANVVGPRNV 195 >6BWL-A nrPDB Length = 328 Score = 38.8 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 31/174 (17%), Positives = 56/174 (32%), Gaps = 26/174 (14%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 +L+TG + IG + RL D + + + A + +Q Sbjct: 3 ILVTGGAGFIGRWVVKRLLQDKHEVWILDNLANSTTAN------ITEFAHDLNLKQCIQG 56 Query: 66 DVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQA 125 D++D K VA E + L A + + + D + + + +GT +L+ Sbjct: 57 DIKDKKLVAQLFENNSFDLCYHL--AASINVQDSI-----DDARATFENDTIGTFNLLEQ 109 Query: 126 FLPD----------MKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCES 169 L M + + L + Y SK A E + S Sbjct: 110 CLNYDVKMVFMSTCMVYDKA---TNIQGISELDPIKPASPYAGSKIAAENMVLS 160 >1ZZE-A nrPDB Length = 342 Score = 38.8 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 34/163 (20%), Positives = 61/163 (37%), Gaps = 25/163 (15%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 ++VL+TG + + H+ +L + + L + W+ A PG E Sbjct: 10 EGSLVLVTGANGFVASHVVEQLLEHGYKVRGTARSASKLANLQKRWD-----AKYPGRFE 64 Query: 62 TLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 T V + A + V +G AG+ + + + V+ + GT+ Sbjct: 65 TA---VVEDMLKQGAYDEVIKG-------AAGVAHIASVVSFSNK-YDEVVTPAIGGTLN 113 Query: 122 MLQAFL--PDMKRRGSGRVLVTGS-VGGLMGLPF-NDVYCASK 160 L+A P +K R ++T S V L+ P +Y K Sbjct: 114 ALRAAAATPSVK-----RFVLTSSTVSALIPKPNVEGIYLDEK 151 >1KEU-A nrPDB Length = 361 Score = 38.0 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 31/211 (14%), Positives = 57/211 (27%), Gaps = 52/211 (24%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 +LITG + IG + + + + L G L + + E Sbjct: 3 ILITGGAGFIGSAVVRHIIK---NTQDTVVNIDKLTYAGNLESLSDISESNRYNFE--HA 57 Query: 66 DVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASV-------LDVNVVG 118 D+ DS + E+ + E V ++ N+VG Sbjct: 58 DICDSAEITRIFEQY--------------QPDAVMHLAAESHVDRSITGPAAFIETNIVG 103 Query: 119 TVRMLQAFLPDMKRRGSGRV-------LVTGSVGGLMGLPF------------------- 152 T +L+ G + + T V G + P Sbjct: 104 TYALLEVARKYWSALGEDKKNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTAYAP 163 Query: 153 NDVYCASKFALEGLCESLAVLLLPFGVHLSL 183 + Y ASK + + L + + + Sbjct: 164 SSPYSASKASSDHLVRAWRRTYGLPTIVTNC 194 >6GCS-E nrPDB Length = 375 Score = 37.7 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 27/167 (16%), Positives = 57/167 (34%), Gaps = 27/167 (16%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 + G + +G +L +LA + Y + + + G + Sbjct: 52 TGYTATVFGANGFLGSYLTAKLAKHGTTVVVPYR--------EEMAKRHLKVTGDLGVVN 103 Query: 62 TLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVR 121 L++D+R+ +S+ A D++V L+G DV+V G R Sbjct: 104 FLEMDLRNLESIDEAVR-----HSDIVVN-----LIGREYETKNFNY---YDVHVEGARR 150 Query: 122 MLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCE 168 + +A K+ R + + + P + +K E + + Sbjct: 151 IAEAV----KKHNIARYIHVSAFNAEIDSPSEFNH--TKGLGEQVTK 191 >3SXP-A nrPDB Length = 362 Score = 37.7 bits (86), Expect = 0.007, Method: Composition-based stats. Identities = 29/201 (14%), Positives = 58/201 (28%), Gaps = 31/201 (15%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYAT---LRDLKTQGRLWEAARALACPP 57 + +LITG + +G +LA + ++ V L + R Sbjct: 8 LENQTILITGGAGFVGSNLAFHFQENHPKAKVVVLDKFRSNTLFSNNRPSSLGHFKNLIG 67 Query: 58 GSLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVV 117 E + D+ + + + D L A + L V+ N Sbjct: 68 FKGEVIAADINNPLDLRRLEKL----HFDYLFHQAAVSDTTMLNQ------ELVMKTNYQ 117 Query: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDV-----------YCASKFALEGL 166 + +L+ R +V+ S G+ G Y SK ++ Sbjct: 118 AFLNLLEIA-----RSKKAKVIYASS-AGVYGNTKAPNVVGKNESPENVYGFSKLCMDEF 171 Query: 167 CESLAVLLLPFGVH-LSLIEC 186 S + + G+ ++ Sbjct: 172 VLSHSNDNVQVGLRYFNVYGP 192 >4QUK-A nrPDB Length = 319 Score = 37.7 bits (86), Expect = 0.008, Method: Composition-based stats. Identities = 54/273 (19%), Positives = 94/273 (34%), Gaps = 43/273 (15%) Query: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 VV +TG S I L L + V AT+RD ++ ++ Sbjct: 2 VVCVTGASGYIASWLVRLLLHRG---YTVKATVRDPNDPKKVD-------------HLVK 45 Query: 65 LDVRDSKSVAAARERVTEGRVDVLVC-NAGLGLLG-PLEALGEDAVASVLDVNVVGTVRM 122 LD + + EG D +V G+ P +D A ++D + GT+ + Sbjct: 46 LDGAKERLQLFKANLLEEGAFDSVVQGCHGVFHTASPFYHDVKDPQAELIDPALKGTLNV 105 Query: 123 LQAFL--PDMKRRGSGRVLVTGSVGGLMGL-----PFNDVYCA--------SKFAL-EGL 166 L + P +K RV++T S+ + P V +K L + Sbjct: 106 LNSCAKSPSLK-----RVVLTSSIAAVAYNGKPRTPDVVVDETWFTDADFCAKSNLWYVV 160 Query: 167 CESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQV 226 +LA V + I+ ++ A + L P VL+ + + A + Sbjct: 161 SATLAEEAAWKFVKENNIDMVTINPAMVIGPLLQP--VLNTSAAAILN--LINGAQTFPN 216 Query: 227 FREAAQNPEEVAEVFLTALRAPKPTLRYFTTER 259 N ++VA + A + R+ ER Sbjct: 217 ASFGWVNVKDVANAHILAYENASASGRHCLVER 249 >5K1S-A nrPDB Length = 362 Score = 36.9 bits (84), Expect = 0.011, Method: Composition-based stats. Identities = 22/88 (25%), Positives = 30/88 (34%), Gaps = 7/88 (7%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 A VLITG S G+GL D ++ V ++ ++ + A A Sbjct: 183 AGETVLITGASGGVGLSSVQLARLDGARVIAVTSSEAKVQ----ALKEAGADEVIVSRGL 238 Query: 62 TLQLDVRDSKS---VAAARERVTEGRVD 86 DVR V A E V D Sbjct: 239 DFASDVRKRTQGAGVDVAVEIVGSATFD 266 >4J6F-A nrPDB Length = 382 Score = 36.5 bits (83), Expect = 0.015, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 21/64 (32%), Gaps = 1/64 (1%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 A VL+TG S G+G + ++LA A + A E Sbjct: 206 AGETVLVTGASGGVGSAI-IQLARARGAVPIAVAGPGKEAAMLDIGAQAVVTRGQGDLAE 264 Query: 62 TLQL 65 ++ Sbjct: 265 AVEA 268 >1OC2-A nrPDB Length = 348 Score = 36.1 bits (82), Expect = 0.021, Method: Composition-based stats. Identities = 28/200 (14%), Positives = 57/200 (28%), Gaps = 40/200 (20%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 +++TG + IG + + ++ EA +E + Sbjct: 7 IIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNKANLEAI-----LGDRVELVVG 61 Query: 66 DVRDSKSVAAARERVTEGRVDVLVCNAGLGL-LGPLEALGEDAVASVLDVNVVGTVRMLQ 124 D+ D++ V + D +V A L + N +GT +L+ Sbjct: 62 DIADAELVDKLAAKA-----DAIVHYAAESHNDNSLNDPSP-----FIHTNFIGTYTLLE 111 Query: 125 AFLPDMKRRGSGRVLVTGSVGGLMG----LPF-----------------NDVYCASKFAL 163 A R + T V G + LP + Y ++K A Sbjct: 112 AARKYDIRFHH---VSTDEVYGDLPLREDLPGHGEGPGEKFTAETNYNPSSPYSSTKAAS 168 Query: 164 EGLCESLAVLLLPFGVHLSL 183 + + ++ + Sbjct: 169 DLIVKAWVRSFGVKATISNC 188 >2PZM-A nrPDB Length = 330 Score = 36.1 bits (82), Expect = 0.021, Method: Composition-based stats. Identities = 22/128 (17%), Positives = 40/128 (31%), Gaps = 20/128 (15%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 +LITG + +G +L + + R + P L ++ Sbjct: 23 ILITGGAGCLGSNLIEHWLPQGHEILVID----------NFATGKREVLPPVAGLSVIEG 72 Query: 66 DVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQA 125 V D+ + A + V V +A D A NV G++ + +A Sbjct: 73 SVTDAGLLERAFDSFKPTHV---VHSAAAYKD-------PDDWAEDAATNVQGSINVAKA 122 Query: 126 FLPDMKRR 133 +R Sbjct: 123 ASKAGVKR 130 >2PK3-A nrPDB Length = 321 Score = 36.1 bits (82), Expect = 0.024, Method: Composition-based stats. Identities = 38/224 (16%), Positives = 66/224 (29%), Gaps = 50/224 (22%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 LITG + +G +LA L + F +R ++E + L Sbjct: 15 ALITGVAGFVGKYLANHLTEQNVEVFG----------------TSRNNEAKLPNVEMISL 58 Query: 66 DVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVAS--VLDVNVVGTVRML 123 D+ DS+ V + + L ++ + + NV GT+ +L Sbjct: 59 DIMDSQRVKKVISDIKPDY---------IFHLAAKSSVKDSWLNKKGTFSTNVFGTLHVL 109 Query: 124 QAFLPDMKRRGSGRVLVTGS-------------VGGLMGLPFNDVYCASKFALEGLCESL 170 A R+L GS V L Y SK ++ L Sbjct: 110 DAVRDSNLDC---RILTIGSSEEYGMILPEESPVSEENQLRPMSPYGVSKASVGMLARQY 166 Query: 171 AVLLLPFGV---HLSLIEC----GPVHTAFMEKVLGSPEEVLDR 207 + + I G V F ++++ E + Sbjct: 167 VKAYGMDIIHTRTFNHIGPGQSLGFVTQDFAKQIVDIEMEKQEP 210 >4R1U-A nrPDB Length = 349 Score = 35.4 bits (80), Expect = 0.034, Method: Composition-based stats. Identities = 24/152 (15%), Positives = 42/152 (27%), Gaps = 25/152 (16%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETL 63 V +TG I L L D K + L L Sbjct: 28 QTVCVTGAGGFIASWLVKLLLERGYTVRGTVRNPEDPKNG-----HLKELEGARERLTLH 82 Query: 64 QLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLG-PLEALGEDAVASVLDVNVVGTVRM 122 ++D+ D +S+ + V G G+ P+ ++ + V Sbjct: 83 KVDLLDLQSI----QSVVHG-------CHGVFHTASPVTDNPDE--------MLEPAVNG 123 Query: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFND 154 + + RV+ T S+G + P Sbjct: 124 TKNVIIASAEAKVRRVVFTSSIGTVYMDPNTS 155 >1BXK-A nrPDB Length = 355 Score = 35.4 bits (80), Expect = 0.038, Method: Composition-based stats. Identities = 36/197 (18%), Positives = 64/197 (32%), Gaps = 32/197 (16%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 +LITG + IG L + ++ S + V L L A++ + Sbjct: 4 ILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSLAPVAQSERFAFEKV----- 58 Query: 66 DVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQA 125 D+ D +A TE + D ++ A + A+ ++ N+VGT +L+A Sbjct: 59 DICDRAELARVF---TEHQPDCVMHLAAESHVDRSIDGP----AAFIETNIVGTYTLLEA 111 Query: 126 FLPDM-------KRRGSGRVLVTGSVGG-----------LMGLPFNDVYCASKFALEGLC 167 K + T V G + Y ASK + + L Sbjct: 112 ARAYWNALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPYSASKASSDHLV 171 Query: 168 ESLAVLLL-PFGVHLSL 183 + P + + Sbjct: 172 RAWLRTYGLPTLIT-NC 187 >2P4H-X nrPDB Length = 322 Score = 33.4 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 46/288 (15%), Positives = 79/288 (27%), Gaps = 52/288 (18%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 V +TG + +G + L + + V T+R + R L L Sbjct: 1 KGRVC-VTGGTGFLGSWIIKSLLENG---YSVNTTIRADPERKRDVSFLTNLPGASEKLH 56 Query: 62 TLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVL-DVNVVGTV 120 D+ + S AAA E G+ ++ V G + Sbjct: 57 FFNADLSNPDSFAAAIEGCV-----------GIFHTASPIDFAVSEPEEIVTKRTVDGAL 105 Query: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGL----------------------PFNDVYCA 158 +L+A + + + T S + PF Y Sbjct: 106 GILKACVNSKTVKRF---IYTSSGSAVSFNGKDKDVLDESDWSDVDLLRSVKPFGWNYAV 162 Query: 159 SKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQ 218 SK L E + + I+ V T + ++G I Sbjct: 163 SK----TLAEKAVLEFGEQ----NGID---VVTLILPFIVGRFVCPKLPDSIEKALVLVL 211 Query: 219 YLAHSKQVFREAAQNPEEVAEVFLTALRAPKPTLRYFTTERFLPLLRM 266 V R + ++VA + L P RY + +P+ M Sbjct: 212 GKKEQIGVTRFHMVHVDDVARAHIYLLENSVPGGRYNCSPFIVPIEEM 259 >1RPN-A nrPDB Length = 335 Score = 33.4 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 21/81 (25%), Positives = 33/81 (40%), Gaps = 7/81 (8%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 M R+ L+TG + G +LA L + + A R T+ RL E G + Sbjct: 13 MTRS-ALVTGITGQDGAYLAKLLLEKGYRVHGLVA-RRSSDTRWRLREL-----GIEGDI 65 Query: 61 ETLQLDVRDSKSVAAARERVT 81 + D+ D+ SV A + Sbjct: 66 QYEDGDMADACSVQRAVIKAQ 86 >2HUN-A nrPDB Length = 336 Score = 33.4 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 34/176 (19%), Positives = 57/176 (32%), Gaps = 27/176 (15%) Query: 7 LITGCSSGIGLH-LAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 L+TG IG + + L P D G + L P ++ Sbjct: 7 LVTGGMGFIGSNFIRYILEKHPDWEVINI----DKLGYGSNPANLKDLEDDP-RYTFVKG 61 Query: 66 DVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQA 125 DV D + V +VD +V A + + + L NV+GT +L++ Sbjct: 62 DVADYELVKELVR-----KVDGVVHLAAESHVDRSIS-SPEIF---LHSNVIGTYTLLES 112 Query: 126 FLPDMKRRGSGRV--------LVTGSVGGLMGLPFNDVYCASKFA----LEGLCES 169 + V ++ GS L + Y A+K A + G + Sbjct: 113 IRRENPEVRFVHVSTDEVYGDILKGSFTENDRLMPSSPYSATKAASDMLVLGWTRT 168 >6DEB-A nrPDB Length = 285 Score = 33.0 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 22/111 (19%), Positives = 41/111 (36%), Gaps = 18/111 (16%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 + +I G S+ +G +A L + + + +DL R A + G + Sbjct: 158 LEGKDAVIIGASNIVGRPMATMLLNAGATVSVCHIKTKDLSLYTRQ---ADLIIVAAGCV 214 Query: 61 ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASV 111 L+ D+ V EG V+V + G+ L + +G+ V Sbjct: 215 NLLRSDM------------VKEG---VIVVDVGINRLESGKIVGDVDFEEV 250 >5F5N-A nrPDB Length = 289 Score = 33.0 bits (74), Expect = 0.17, Method: Composition-based stats. Identities = 10/83 (12%), Positives = 24/83 (28%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 62 +L+TG + G L + + + + + Sbjct: 1 NRTILVTGATGTQGGATVRALLARGRPVRALVRDPGTDAARALAAAGVSLVTGDLNDQAS 60 Query: 63 LQLDVRDSKSVAAARERVTEGRV 85 L+ + D V + + +T G + Sbjct: 61 LRAAMADVHGVFSVQTFMTPGGL 83 >2EXX-A nrPDB Length = 306 Score = 33.0 bits (74), Expect = 0.19, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 24/78 (30%), Gaps = 9/78 (11%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 62 + +V++ G + G +A L D + +V R A E Sbjct: 11 KKLVVVFGGTGAQGGSVARTLLEDGTFKVRVVT---------RNPRKKAAKELRLQGAEV 61 Query: 63 LQLDVRDSKSVAAARERV 80 +Q D D + A Sbjct: 62 VQGDQDDQVIMELALNGA 79 >2GGS-A nrPDB Length = 273 Score = 33.0 bits (74), Expect = 0.20, Method: Composition-based stats. Identities = 25/119 (21%), Positives = 45/119 (37%), Gaps = 28/119 (23%) Query: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLD 66 LITG S +G+ L+ RL S+ + KVY + +LD Sbjct: 4 LITGASGQLGIELS-RLLSERHEVIKVYNSSEIQG--------------------GYKLD 42 Query: 67 VRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQA 125 + D + + + + R DV++ A + + E E A +N +++A Sbjct: 43 LTDFPRLE---DFIIKKRPDVIINAAAMTDVDKCEIEKEKAYK----INAEAVRHIVRA 94 >5UZH-A nrPDB Length = 345 Score = 32.3 bits (72), Expect = 0.28, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 24/66 (36%), Gaps = 1/66 (1%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETL 63 V LITG + G +LA L + + T GR+ + + + L Sbjct: 2 KVALITGITGQDGSYLAEFLLEKGYMVYGIIRRSSSFNT-GRVEHLYKDIHITKAKFKLL 60 Query: 64 QLDVRD 69 D+ D Sbjct: 61 YGDLTD 66 >1N7G-A nrPDB Length = 381 Score = 32.3 bits (72), Expect = 0.32, Method: Composition-based stats. Identities = 42/277 (15%), Positives = 70/277 (25%), Gaps = 39/277 (14%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 62 R + LITG + G +L L + + + TQ ++ Sbjct: 28 RKIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKL 87 Query: 63 LQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 D+ D+ S+ + + + D + A + + DV G +R+ Sbjct: 88 HYADLTDASSLRRWIDVI---KPDEVYNLAAQSHVAVSFEIP----DYTADVVATGALRL 140 Query: 123 LQAFLPDMKRRGS-------GRVLVTGSV----GGLMGLPFNDVYCASKFALEGLCESLA 171 L+A G G + GS Y ASK A + Sbjct: 141 LEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNY- 199 Query: 172 VL----LLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVF 227 G+ + E + R R L + Sbjct: 200 REAYGLFACNGILFNHESP------------RRGENFVTRKITRALGRIKVGLQTKLFLG 247 Query: 228 REAAQN----PEEVAEVFLTALRAPKPTLRYFTTERF 260 A + E L+ KP TE Sbjct: 248 NLQASRDWGFAGDYVEAMWLMLQQEKPDDYVVATEEG 284 >5B6K-A nrPDB Length = 366 Score = 32.3 bits (72), Expect = 0.34, Method: Composition-based stats. Identities = 22/147 (14%), Positives = 47/147 (31%), Gaps = 21/147 (14%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET- 62 T V ++G + I H+ +L + + + + + G Sbjct: 22 TTVFVSGATGFIAQHVVRQLLDQNYKVIGSVRS-------AEKGDHLKNVIFKGGDFNYE 74 Query: 63 LQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 + D+ D + E+ G+ D+ V + + L ++ V Sbjct: 75 IVKDISDPTAFDHVFEK--HGK-DIKV----VLHTASPFHFNTTDIEKDL---LIPAVNG 124 Query: 123 LQAFLPDMKR---RGSGRVLVTGSVGG 146 + L +K+ + RV+VT S Sbjct: 125 TKGILESIKKYAAQTVERVVVTSSFAA 151 >3CT4-A nrPDB Length = 332 Score = 31.9 bits (71), Expect = 0.35, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 30/80 (37%), Gaps = 4/80 (5%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 + V L++G SG A + S V + T +++EA ++ G L Sbjct: 45 SGKVALVSGGGSGHEPAHA-GFVGEGMLSAAVCGAIFTSPTPDQIYEAIKSADEGAGVLL 103 Query: 62 TLQ---LDVRDSKSVAAARE 78 ++ DV + + E Sbjct: 104 IIKNYLGDVMNFEMAREMAE 123 >4UUP-A nrPDB Length = 341 Score = 31.9 bits (71), Expect = 0.43, Method: Composition-based stats. Identities = 28/103 (27%), Positives = 40/103 (38%), Gaps = 12/103 (11%) Query: 6 VLITGCSSGIGLHLAVRLAS-DPSQSFKVYATLRDLKTQGRLWEAA----RALACPPGSL 60 VLITG + IG LA R+A D KV L ++ + E + A P + Sbjct: 7 VLITGAAGQIGYALAFRIAKGDLFGDRKVVLHLLEIPPAMKALEGVCMELQDCAFPTLAG 66 Query: 61 ETLQLDVRDS-KSVAAARERVTE------GRVDVLVCNAGLGL 96 D ++ K V A + R D+L NAG+ Sbjct: 67 VVATDDPEEAFKDVDVAFLVGSFPRKPGMERADLLEKNAGIFK 109 >3SC6-A nrPDB Length = 287 Score = 31.5 bits (70), Expect = 0.48, Method: Composition-based stats. Identities = 22/154 (14%), Positives = 47/154 (30%), Gaps = 23/154 (14%) Query: 28 SQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAARERVTEGRVDV 87 + +V T + + +L E + LD+ + V + + R + Sbjct: 3 AMKERVIITGANGQLGKQLQEELNPEEYDIYPFDKKLLDITNISQVQQVVQEI---RPHI 59 Query: 88 LVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGL 147 ++ A E +N +G + A + +++ + Sbjct: 60 IIHCAAYTK----VDQAEKERDLAYVINAIGARNV--AVASQLV---GAKLVYISTDYVF 110 Query: 148 MG----------LPF-NDVYCASKFALEGLCESL 170 G P ++Y ASK+A E + L Sbjct: 111 QGDRPEGYDEFHNPAPINIYGASKYAGEQFVKEL 144 >6I3M-E nrPDB Length = 381 Score = 31.5 bits (70), Expect = 0.51, Method: Composition-based stats. Identities = 19/117 (16%), Positives = 38/117 (32%), Gaps = 5/117 (4%) Query: 4 TVVLITGC--SSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 V + G SS G+ A + A L L ++ + + Sbjct: 263 KAVFVNGGTISSNSGVSSVCECAREFRTPVFAVAGLYKLSPL-YPFDVEKFVEFGGSQRI 321 Query: 62 TLQLDVRDS-KSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVV 117 ++D R +V + V +D+ + N G + + D +DV++ Sbjct: 322 LPRMDPRKRLDTVNQITDYVPPENIDIYITNVGGFNPSFIYRIAWDNYKQ-IDVHLD 377 >6GPK-A nrPDB Length = 373 Score = 31.5 bits (70), Expect = 0.54, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 26/79 (32%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 62 R V LITG + G +LA L + + T A G+++ Sbjct: 24 RNVALITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSFNTGRIEHLYKNPQAHIEGNMKL 83 Query: 63 LQLDVRDSKSVAAARERVT 81 D+ DS + V Sbjct: 84 HYGDLTDSTCLVKIINEVK 102 >1DB3-A nrPDB Length = 372 Score = 31.1 bits (69), Expect = 0.76, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 25/78 (32%), Gaps = 1/78 (1%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETL 63 V LITG + G +LA L + + T+ R+ + Sbjct: 2 KVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTE-RVDHIYQDPHTCNPKFHLH 60 Query: 64 QLDVRDSKSVAAARERVT 81 D+ D+ ++ V Sbjct: 61 YGDLSDTSNLTRILREVQ 78 >3PVZ-A nrPDB Length = 399 Score = 30.7 bits (68), Expect = 0.87, Method: Composition-based stats. Identities = 20/123 (16%), Positives = 44/123 (35%), Gaps = 6/123 (4%) Query: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLD 66 L+ G + IG + + Q V + + + + + G +T LD Sbjct: 39 LVLGGAGSIGQAVTKEIFKRNPQKLHVV-DISENNMVELVRDIRSSFGYINGDFQTFALD 97 Query: 67 VRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAF 126 + S+ +G+ D ++ + L + + ++DVNV T + +Q Sbjct: 98 IG---SIEYDAFIKADGQYDYVLNLSALKHVR--SEKDPFTLMRMIDVNVFNTDKTIQQS 152 Query: 127 LPD 129 + Sbjct: 153 IDA 155 >4E0B-A nrPDB Length = 313 Score = 30.7 bits (68), Expect = 0.93, Method: Composition-based stats. Identities = 25/116 (21%), Positives = 37/116 (31%), Gaps = 24/116 (20%) Query: 2 ARTVVLITGCSSGIGLHLAVRL----------------------ASDPSQS-FKVYATLR 38 A V +I G + GIG LA+ L A+D S V Sbjct: 3 AMKVAVI-GAAGGIGQALALLLKNRLPAGSDLALYDIAPVTPGVAADLSHIPTHVSIKGY 61 Query: 39 DLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGL 94 + E A + G +D D +V A + R+ V+ NA + Sbjct: 62 AGEDPTPALEGADVVLISAGVARKPGMDRADLFNVNAGIVKSLAERIAVVCPNACI 117 >5ENV-A nrPDB Length = 347 Score = 30.3 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 21/95 (22%), Positives = 36/95 (37%), Gaps = 11/95 (11%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASD-PSQSFKVYATLRDLKTQGRLWEAARALACPPGS 59 MA V I+G + G+G LAV+ A + + E R++ Sbjct: 168 MAGHWVAISGAAGGLG-SLAVQYAKAMGYRVLGIDGG-------EGKEELFRSIGGEVFI 219 Query: 60 LETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGL 94 T + D+ +V A + G ++V V A + Sbjct: 220 DFTKEKDI--VGAVLKATDGGAHGVINVSVSEAAI 252 >1O89-A nrPDB Length = 345 Score = 30.3 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 8/30 (26%), Positives = 12/30 (40%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYA 35 +++TG S G+G L Q V Sbjct: 171 IVVTGASGGVGSTAVALLHKLGYQVVAVSG 200 >1IQP-A nrPDB Length = 327 Score = 30.0 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 17/55 (30%), Positives = 26/55 (47%), Gaps = 10/55 (18%) Query: 233 NPEEVAEVFLTALRAPKPTLRYFTTERFL--PLLRMRLDDPSGSNYVTAMHREVF 285 PE++ E+ L AL+ + L LL+ L SG + + MH+EVF Sbjct: 235 RPEDIREMMLLALK-----GNFLKAREKLREILLKQGL---SGEDVLVQMHKEVF 281 >4EJ6-A nrPDB Length = 370 Score = 29.6 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 30/94 (31%), Gaps = 11/94 (11%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61 A + V I G IGL + + + R LA G+ Sbjct: 182 AGSTVAILGGGV-IGLLTVQLARLAGATTVILST----------RQATKRRLAEEVGATA 230 Query: 62 TLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLG 95 T+ D A + G VDV++ AG+ Sbjct: 231 TVDPSAGDVVEAIAGPVGLVPGGVDVVIECAGVA 264 >2X86-A nrPDB Length = 357 Score = 29.6 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 8/36 (22%), Positives = 16/36 (44%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRD 39 ++++TG + IG ++ L V L+D Sbjct: 47 RMIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKD 82 >1YXY-A nrPDB Length = 234 Score = 29.6 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 8/57 (14%), Positives = 18/57 (31%), Gaps = 7/57 (12%) Query: 128 PDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLI 184 M++ G ++ LP +Y + + L A G+ + + Sbjct: 9 KLMEQLKGGIIV------SCQALPGEPLYSET-GGIMPLMAKAAQEAGAVGIRANSV 58 >4K28-A nrPDB Length = 269 Score = 29.2 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 14/33 (42%), Gaps = 1/33 (3%) Query: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVY 34 A L+ GC G+G +A LA S + Sbjct: 124 AGKRALVIGCG-GVGSAIAYALAEAGIASITLC 155 >3N58-A nrPDB Length = 464 Score = 29.2 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 8/30 (26%), Positives = 13/30 (43%), Gaps = 1/30 (3%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQS 30 MA V ++ G +G A LA ++ Sbjct: 245 MAGKVAVVCGYGD-VGKGSAQSLAGAGARV 273 >5JJC-A nrPDB Length = 342 Score = 29.2 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 16/34 (47%) Query: 10 GCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQ 43 G SSGI + A+RLA D + L D + Sbjct: 275 GGSSGINIAGAIRLAKDLGPGHTIVTVLCDYGNR 308 >4A10-A nrPDB Length = 447 Score = 29.2 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 24/144 (16%), Positives = 41/144 (28%), Gaps = 24/144 (16%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 62 +VLI G S G+G A++ + + + R + + Sbjct: 221 GDIVLIWGASGGLG-SYAIQFVKNGGGIPVAVVSSAQKEAAVRALGCDLVINRAELGITD 279 Query: 63 LQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 D D + V ++ + ++V AG E G Sbjct: 280 DIAD--DPRRVVETGRKLAK----LVVEKAGREPDIVFEHTGRVTF-------------- 319 Query: 123 LQAFLPDMKRRGSGRVLVTGSVGG 146 L + R G V+ GS G Sbjct: 320 ---GLSVIVARRGGTVVTCGSSSG 340 >1IXR-A nrPDB Length = 191 Score = 29.2 bits (64), Expect = 2.9, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 28/75 (37%), Gaps = 3/75 (4%) Query: 11 CSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGS---LETLQLDV 67 +SG+G LA R+A + + + EA ALA + LD+ Sbjct: 111 SASGVGRRLAERIALELKGKVPPHLLAGEKVESEAAEEAVMALAALGFKEAQARAVVLDL 170 Query: 68 RDSKSVAAARERVTE 82 A A++ + E Sbjct: 171 LAQNPKARAQDLIKE 185 >4EUF-A nrPDB Length = 418 Score = 28.8 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 22/48 (45%), Gaps = 1/48 (2%) Query: 3 RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAA 50 + V+++ G SSG GL + +A ++ + + T R+ A Sbjct: 61 KKVLIV-GASSGFGLATRISVAFGGPEAHTIGVSYETGATDRRIGTAG 107 >1QQV-A nrPDB Length = 67 Score = 28.8 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 21/57 (36%), Gaps = 11/57 (19%) Query: 84 RVDVLVCNA------GLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRG 134 +DVLV A G+ L ++ +V G R A LP K++ Sbjct: 8 PLDVLVNTAAEDLPRGVDPSRKENHLSDEDFKAVF-----GMTRSAFANLPLWKQQN 59 >4AY7-A nrPDB Length = 348 Score = 28.8 bits (63), Expect = 3.2, Method: Composition-based stats. Identities = 13/75 (17%), Positives = 25/75 (33%), Gaps = 9/75 (12%) Query: 38 RDLKTQGRLWEAARALACPPGSLETLQLDVRDS--------KSVAAARERVTEGRVDVLV 89 L + ++ A + + +V + A + EG +DVL Sbjct: 264 EGLSVEEKIGSAKKGKEVIGTRARLV-GNVSSPFTLLPGPVDKIKAEAKEALEGGIDVLA 322 Query: 90 CNAGLGLLGPLEALG 104 G+ + PLE + Sbjct: 323 PGCGIAPMTPLENVK 337 >4A5O-A nrPDB Length = 286 Score = 28.4 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 14/80 (17%), Positives = 29/80 (36%), Gaps = 1/80 (1%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQL 65 ++ G S+ +G +A+ L + RDL + A PG ++ + Sbjct: 164 AVVVGASNIVGRPMALELLLGGCTVTVTHRFTRDLADHVSRADLVVVAAGKPGLVKG-EW 222 Query: 66 DVRDSKSVAAARERVTEGRV 85 + + R +GR+ Sbjct: 223 IKEGAIVIDVGINRQADGRL 242 >6NBY-D nrPDB Length = 529 Score = 28.4 bits (62), Expect = 4.5, Method: Composition-based stats. Identities = 24/141 (17%), Positives = 42/141 (29%), Gaps = 16/141 (11%) Query: 142 GSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTA-----FMEK 196 S+ L LP + A G S A L + + L G + T + + Sbjct: 382 CSLASL-ALPGMSGFVAELMVFIGFATSDAYSLPFRVIVVFLAAVGVILTPIYLLSMLRE 440 Query: 197 VLGSPEE---VLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVFLTALRAPKPTLR 253 + PE V + R +A P+ + +++ T + Sbjct: 441 IFYGPENKELVEHEALVDAEPREVFIIACLLVPIIGIGLYPKLLTQIY------DATTGQ 494 Query: 254 YFT-TERFLPLLRMRLDDPSG 273 LP L + + P G Sbjct: 495 VIARAREVLPTLAQQTEQPLG 515 >2Z95-A nrPDB Length = 345 Score = 28.0 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 10/36 (27%), Positives = 14/36 (38%), Gaps = 2/36 (5%) Query: 1 MARTVVLITGCSSGI-GLHLAVRLASDPSQSFKVYA 35 M+ LITG G G +LA L + + Sbjct: 1 MSGKRALITG-IRGQDGAYLAKLLLEKGYEVYGADR 35 >4H05-A nrPDB Length = 273 Score = 28.0 bits (61), Expect = 5.1, Method: Composition-based stats. Identities = 22/103 (21%), Positives = 33/103 (32%), Gaps = 3/103 (2%) Query: 13 SGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKS 72 G G L V++A+ + + R + R + G E + V ++ Sbjct: 39 RGGGRELFVKVAALGAGVGLLGEAERLVWLAEVGIPVPRVVE--GGGDERVAWLVTEAVP 96 Query: 73 VAAARERVT-EGRVDVLVCNAGLGLLGPLEALGEDAVASVLDV 114 A R E R+DV V AGL L V Sbjct: 97 GRPASARWPREQRLDVAVALAGLARSLHALDWERCPFDRSLAV 139 >1YFM-A nrPDB Length = 488 Score = 28.0 bits (61), Expect = 5.4, Method: Composition-based stats. Identities = 20/136 (14%), Positives = 48/136 (35%), Gaps = 22/136 (16%) Query: 55 CPPGSLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDV 114 P S+ +++ ++++ +V NA + G + V+ Sbjct: 340 EPGSSIMPGKVNPTQNEALTQVCVQVMG-------NNAAITFAGSQGQFELNVFKPVMIA 392 Query: 115 NVVGTVRMLQAFLPDMK-------RRGSGRV--LVTGSVGGLMG-LPFNDVYCASK---- 160 N++ ++R++ + + R+ L+T S+ + P ASK Sbjct: 393 NLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAASKVAKN 452 Query: 161 FALEGLC-ESLAVLLL 175 +G+ + A+ L Sbjct: 453 AHKKGITLKESALELG 468 >4EJ0-A nrPDB Length = 342 Score = 28.0 bits (61), Expect = 5.8, Method: Composition-based stats. Identities = 20/128 (15%), Positives = 33/128 (25%), Gaps = 23/128 (17%) Query: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLD 66 ++TG + IG +L L L L + + Sbjct: 16 IVTGAAGFIGANLVKALNERGETRIIAVDNLTRADKFKNL----------------VDCE 59 Query: 67 VRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAF 126 + D ER G + + G E ++D N R +A Sbjct: 60 IDDYLDKTEFVERFARGDFGKV---RAVFHEGACSDTMETDGRYMMDNN----FRYSRAV 112 Query: 127 LPDMKRRG 134 L +G Sbjct: 113 LDACLAQG 120 >1Z1W-A nrPDB Length = 780 Score = 28.0 bits (61), Expect = 5.8, Method: Composition-based stats. Identities = 5/26 (19%), Positives = 15/26 (57%) Query: 59 SLETLQLDVRDSKSVAAARERVTEGR 84 + +++DVRD ++ + ++ G+ Sbjct: 328 NTHPIEVDVRDPDEISQIFDEISYGK 353 >4UUM-A nrPDB Length = 341 Score = 28.0 bits (61), Expect = 6.2, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 21/66 (31%), Gaps = 2/66 (3%) Query: 67 VRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAF 126 V D +E T+ VDVL + + +G A + +A Sbjct: 191 VADLTQATFTKEGKTQKVVDVL--DHDYVFDTFFKKIGHRAWDILEHRGFTSAASPTKAA 248 Query: 127 LPDMKR 132 + MK Sbjct: 249 IQHMKA 254 >5NUE-A nrPDB Length = 332 Score = 27.6 bits (60), Expect = 6.8, Method: Composition-based stats. Identities = 23/124 (18%), Positives = 38/124 (30%), Gaps = 17/124 (13%) Query: 6 VLITGCSSGIGLHLAVRLAS--DPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETL 63 VL+TG + IG L +A V + D+ + + + L Sbjct: 8 VLVTGAAGQIGYALVPMIARGIMLGADQPVILHMLDIPPAAEALNGVK-MELIDAAFPLL 66 Query: 64 QLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRML 123 + V + +V V+V V G +E V+ NV + Sbjct: 67 KGVVATTDAVEGCT------GVNVAVMVGGFPRKEGMER------KDVMSKNVS--IYKS 112 Query: 124 QAFL 127 QA Sbjct: 113 QAAA 116 >4WOK-A nrPDB Length = 336 Score = 27.6 bits (60), Expect = 8.1, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 26/79 (32%), Gaps = 13/79 (16%) Query: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 M+ VL+ G + IG H A LA VY L W Sbjct: 9 MSANNVLVVGGAGFIGSHTAKLLAGQGYAPV-VYDNLSTGHQSAVRW------------G 55 Query: 61 ETLQLDVRDSKSVAAARER 79 + ++ D+ D + E+ Sbjct: 56 DFVEGDILDQARLVETMEK 74 >1IIT-A nrPDB Length = 232 Score = 27.6 bits (60), Expect = 8.1, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 34/75 (45%), Gaps = 6/75 (8%) Query: 16 GLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPG-SLETLQLDVRDSKSVA 74 G +A+++ + F Y ++ G + RA+A + E ++ + S++ Sbjct: 1 GSAMALKVGVVGNPPFVFYGEGKNAAFTGISLDVWRAVAESQKWNSEYVRQN-----SIS 55 Query: 75 AARERVTEGRVDVLV 89 A V EG +D+L+ Sbjct: 56 AGITAVAEGELDILI 70 >5VEG-A nrPDB Length = 178 Score = 27.6 bits (60), Expect = 8.2, Method: Composition-based stats. Identities = 15/91 (16%), Positives = 27/91 (29%), Gaps = 12/91 (13%) Query: 28 SQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAARERVTEGRVDV 87 + T + + + ++ L E Q DV D + D+ Sbjct: 33 AHVVYATMTGNNEEVANIVCDSLTNLNVKVTESEISQTDVADFM------------KADI 80 Query: 88 LVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118 LV A G + G D + ++ G Sbjct: 81 LVVCAYTYDEGAMPEEGLDFYDDLQSTDLTG 111 >5OHX-A nrPDB Length = 504 Score = 27.6 bits (60), Expect = 8.2, Method: Composition-based stats. Identities = 18/110 (16%), Positives = 33/110 (30%), Gaps = 26/110 (23%) Query: 9 TGCSSGIGLHLAVR---------------------LASDPSQSFKVYATLRDLKTQGRLW 47 T ++GIGL +A L + ++ + + + Sbjct: 105 TSGNTGIGLAMAAAVRGYKCIIVMPEKMSDEKISTLYALGAKIIRTPTEASWHSPEAHIS 164 Query: 48 EAARALACPPGSLETLQLD-----VRDSKSVAAARERVTEGRVDVLVCNA 92 A + P S+ Q + A + EG++D LV A Sbjct: 165 VAQKLQKEIPNSIILDQYTNPGNPLAHYDQTAIEIWKQCEGKIDYLVAGA 214 >5N2I-A nrPDB Length = 232 Score = 27.6 bits (60), Expect = 8.4, Method: Composition-based stats. Identities = 8/60 (13%), Positives = 15/60 (25%) Query: 8 ITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDV 67 + G + G LA R A + + + + + DV Sbjct: 24 VLGGTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAELGEGLPVRGMDNAGAAEAGDV 83 >5GXF-A nrPDB Length = 330 Score = 27.3 bits (59), Expect = 9.0, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 13/28 (46%) Query: 6 VLITGCSSGIGLHLAVRLASDPSQSFKV 33 VL+TG + G+G LA + V Sbjct: 153 VLVTGAAGGVGSVATAILAHLGYEVAAV 180 >1IE3-A nrPDB Length = 312 Score = 27.3 bits (59), Expect = 9.0, Method: Composition-based stats. Identities = 23/137 (16%), Positives = 45/137 (32%), Gaps = 19/137 (13%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETL 63 V + G + GIG LA+ L T ++ L++ A L + Sbjct: 2 KVA-VLGAAGGIGQALALLL-----------KTQLPSGSELSLYDIAPVTPGVAVDLSHI 49 Query: 64 QLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRML 123 V+ EG DV++ +AG+ ++ + + +VN ++ Sbjct: 50 PTAVKIKGFSGEDATPALEGA-DVVLISAGVARKPGMDR------SDLFNVNAGIVKNLV 102 Query: 124 QAFLPDMKRRGSGRVLV 140 Q + G + Sbjct: 103 QQVAKTCPKACIGIITN 119 >1JAY-A nrPDB Length = 212 Score = 27.3 bits (59), Expect = 9.2, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 26/71 (36%), Gaps = 4/71 (5%) Query: 4 TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETL 63 V L+ G + +G LA+RLA+ ++ R + R +A Sbjct: 2 RVALL-GGTGNLGKGLALRLATLG---HEIVVGSRREEKAEAKAAEYRRIAGDASITGMK 57 Query: 64 QLDVRDSKSVA 74 D ++ +A Sbjct: 58 NEDAAEACDIA 68 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.141 0.407 Lambda K H 0.267 0.0430 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,383,675 Number of Sequences: 36641 Number of extensions: 650563 Number of successful extensions: 3152 Number of sequences better than 10.0: 296 Number of HSP's better than 10.0 without gapping: 316 Number of HSP's successfully gapped in prelim test: 136 Number of HSP's that attempted gapping in prelim test: 2315 Number of HSP's gapped (non-prelim): 487 length of query: 328 length of database: 10,336,785 effective HSP length: 97 effective length of query: 231 effective length of database: 6,782,608 effective search space: 1566782448 effective search space used: 1566782448 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 59 (27.3 bits)