BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P13188 (809 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4H3S-A nrPDB 1679 0.0 4R3Z-C nrPDB 533 e-151 2RD2-A nrPDB 402 e-112 5BNZ-A nrPDB 379 e-105 3TL4-X nrPDB 378 e-105 4P2B-A nrPDB 365 e-101 5ZDO-A nrPDB 358 6e-99 2HZ7-A nrPDB 337 2e-92 3AII-A nrPDB 223 2e-58 2CFO-A nrPDB 86 8e-17 2O5R-A nrPDB 71 2e-12 4GRI-A nrPDB 69 7e-12 3AL0-C nrPDB 69 1e-11 6B1P-A nrPDB 68 2e-11 6BRL-A nrPDB 64 2e-10 4G6Z-A nrPDB 64 4e-10 5H4V-A nrPDB 62 7e-10 5TGT-A nrPDB 61 2e-09 3AKZ-B nrPDB 60 4e-09 2JA2-A nrPDB 60 5e-09 4A91-A nrPDB 53 4e-07 2CV2-A nrPDB 50 3e-06 3DFY-A nrPDB 33 0.42 6CE1-A nrPDB 30 2.9 5AEG-A nrPDB 30 4.9 3CEI-A nrPDB 29 6.3 2QUB-A nrPDB 29 6.6 >4H3S-A nrPDB Length = 817 Score = 1679 bits (4349), Expect = 0.0, Method: Compositional matrix adjust. Identities = 809/809 (100%), Positives = 809/809 (100%) Query: 1 MSSVEELTQLFSQVGFEDKKVKEIVKNKKVSDSLYKLIKETPSDYQWNKSTRALVHNLAS 60 MSSVEELTQLFSQVGFEDKKVKEIVKNKKVSDSLYKLIKETPSDYQWNKSTRALVHNLAS Sbjct: 1 MSSVEELTQLFSQVGFEDKKVKEIVKNKKVSDSLYKLIKETPSDYQWNKSTRALVHNLAS 60 Query: 61 FVKGTDLPKSELIVNGIINGDLKTSLQVDAAFKYVKANGEASTKMGMNENSGVGIEITED 120 FVKGTDLPKSELIVNGIINGDLKTSLQVDAAFKYVKANGEASTKMGMNENSGVGIEITED Sbjct: 61 FVKGTDLPKSELIVNGIINGDLKTSLQVDAAFKYVKANGEASTKMGMNENSGVGIEITED 120 Query: 121 QVRNYVMQYIQENKERILTERYKLVPGIFADVKNLKELKWADPRSFKPIIDQEVLKLLGP 180 QVRNYVMQYIQENKERILTERYKLVPGIFADVKNLKELKWADPRSFKPIIDQEVLKLLGP Sbjct: 121 QVRNYVMQYIQENKERILTERYKLVPGIFADVKNLKELKWADPRSFKPIIDQEVLKLLGP 180 Query: 181 KDERDLIKKKTKNNEKKKTNSAKKSSDNSASSGPKRTMFNEGFLGDLHKVGENPQAYPEL 240 KDERDLIKKKTKNNEKKKTNSAKKSSDNSASSGPKRTMFNEGFLGDLHKVGENPQAYPEL Sbjct: 181 KDERDLIKKKTKNNEKKKTNSAKKSSDNSASSGPKRTMFNEGFLGDLHKVGENPQAYPEL 240 Query: 241 MKEHLEVTGGKVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAP 300 MKEHLEVTGGKVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAP Sbjct: 241 MKEHLEVTGGKVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAP 300 Query: 301 EYFESIKRMVSWLGFKPWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIK 360 EYFESIKRMVSWLGFKPWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIK Sbjct: 301 EYFESIKRMVSWLGFKPWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIK 360 Query: 361 EDGTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAY 420 EDGTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAY Sbjct: 361 EDGTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAY 420 Query: 421 RVLNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHVFR 480 RVLNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHVFR Sbjct: 421 RVLNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHVFR 480 Query: 481 PAQREYGRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINT 540 PAQREYGRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINT Sbjct: 481 PAQREYGRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINT 540 Query: 541 LGVTTSTTNIQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDNLSDDYEELATIPYRPGT 600 LGVTTSTTNIQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDNLSDDYEELATIPYRPGT Sbjct: 541 LGVTTSTTNIQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDNLSDDYEELATIPYRPGT 600 Query: 601 PEFGERTVPFTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIKVSHTVSFKSLEKDEAGK 660 PEFGERTVPFTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIKVSHTVSFKSLEKDEAGK Sbjct: 601 PEFGERTVPFTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIKVSHTVSFKSLEKDEAGK 660 Query: 661 IIRIHVNYDNKVEEGSKPKKPKTYIQWVPISSKYNSPLRVTETRVYNQLFKSENPSSHPE 720 IIRIHVNYDNKVEEGSKPKKPKTYIQWVPISSKYNSPLRVTETRVYNQLFKSENPSSHPE Sbjct: 661 IIRIHVNYDNKVEEGSKPKKPKTYIQWVPISSKYNSPLRVTETRVYNQLFKSENPSSHPE 720 Query: 721 GFLKDINPESEVVYKESVMEHNFGDVVKNSPWVVDSVKNSEFYVEEDKDSKEVCRFQAMR 780 GFLKDINPESEVVYKESVMEHNFGDVVKNSPWVVDSVKNSEFYVEEDKDSKEVCRFQAMR Sbjct: 721 GFLKDINPESEVVYKESVMEHNFGDVVKNSPWVVDSVKNSEFYVEEDKDSKEVCRFQAMR 780 Query: 781 VGYFTLDKESTTSKVILNRIVSLKDATSK 809 VGYFTLDKESTTSKVILNRIVSLKDATSK Sbjct: 781 VGYFTLDKESTTSKVILNRIVSLKDATSK 809 >4R3Z-C nrPDB Length = 799 Score = 533 bits (1373), Expect = e-151, Method: Compositional matrix adjust. Identities = 320/829 (38%), Positives = 453/829 (54%), Gaps = 75/829 (9%) Query: 1 MSSVEELTQLFSQVGFEDKKVKEIVKNKKVSDSLYKLIKETPSDY--QWNKSTRALVHNL 58 M++++ L+ LF+ +G ++K +E +KN +S L + + +K+T L++ L Sbjct: 25 MAALDSLS-LFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGL 83 Query: 59 ASFVKGTDLPKSELIVNGIINGDLKTSLQVDAAFKYVKANG-EASTKMGMNENSGVGIEI 117 AS ++ D + +V+ I + + T Q+ AA +YV+++ + + GVG+ + Sbjct: 84 ASRLR--DTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIV 141 Query: 118 TEDQVRNYVMQYIQENKERILTERYKLVPGIFADVKNLKELKWADPRSFKPIIDQEVLKL 177 T +Q+ V I ++ ++L ERY G+ + LKWAD + K +D +VL L Sbjct: 142 TPEQIEEAVEAAINRHRPQLLVERYHFNMGLLMG-EARAVLKWADGKMIKNEVDMQVLHL 200 Query: 178 LGPKDERDLIKK---KTKNNEKKKTNSAKKSSDNSASSGPKRTMFNE--GFLGDLHKVGE 232 LGPK E DL KK E+ +AK +N ++ ++ + G HK GE Sbjct: 201 LGPKLEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGE 260 Query: 233 N---------PQAYPELMKEHLEVTGGKVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHN 283 N P L+K+HLE+TGG+VRTRFPPEPNG LHIGH+KAI NFGYAK +N Sbjct: 261 NYKTPGYVVTPHTM-NLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANN 319 Query: 284 GTCYLRFDDTNPEKEAPEYFESIKRMVSWLGFKPWKITYSSDYFDELYRLAEVLIKNGKA 343 G C+LRFDDTNPEKE ++F +I MV+WLG+ P+K+TY+SDYFD+LY A LI+ G A Sbjct: 320 GICFLRFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLA 379 Query: 344 YVCHCTAEEIKRGRGIKEDGTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRM 403 YVCH EE+K G RD+ +E++L F MR GK+ GEA LRM Sbjct: 380 YVCHQRGEELK-----------GHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRM 428 Query: 404 KQDLNSPSPQMWDLIAYRVLNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFY 463 K + D +AYRV PH RTG KW IYPTYD+THCL DS+E+ITHSLCT EF Sbjct: 429 KLVMEDGK---MDPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQ 485 Query: 464 LSRESYEWLCDQVHVFRPAQREYGRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEA 523 R SY WLC+ + V+ P Q EYGRLN+ V+SKRKI QLV VR WDDPRLFTL A Sbjct: 486 ARRSSYFWLCNALDVYCPVQWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTA 545 Query: 524 IRRRGVPPGAILSFINTLGVTTSTTNIQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDN 583 +RRRG PP AI +F +GVT + T ++ E+ VR L DT PR M VL+ + V++ N Sbjct: 546 LRRRGFPPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITN 605 Query: 584 LSDDYEELATIPYRPGTPEFGERTVPFTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIK 643 +P P G VPF +IER+DF E + F RL QPVGL Sbjct: 606 FPAAKSLDIQVPNFPADETKGFHQVPFAPIVFIERTDFKEE-PEPGFKRLAWGQPVGLRH 664 Query: 644 VSHTVSFKSLEKDEAGKIIRIHVNYDNKVEEGSKPKKPKTYIQWVPISSKYNSPLRVTET 703 + + + + K +G + + V +KPK +I WV + PL + E Sbjct: 665 TGYVIELQHVVKGPSGCVESLEVT----CRRADAGEKPKAFIHWV------SQPL-MCEV 713 Query: 704 RVYNQLFKSEN---PSSHPEGFLKDINPESEVVYKESVMEHNFGDVVKNSPWVVDSVKNS 760 R+Y +LF+ +N P+ P GFL D+N S V ++++ + Sbjct: 714 RLYERLFQHKNPEDPTEVPGGFLSDLNLASLHVVDAALVDCSVA---------------- 757 Query: 761 EFYVEEDKDSKEVCRFQAMRVGYFTLDKESTTSKVILNRIVSLKDATSK 809 +K +FQ R+GYF++D +S K++ NR V+LK+ K Sbjct: 758 --------LAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGK 798 >2RD2-A nrPDB Length = 556 Score = 402 bits (1034), Expect = e-112, Method: Compositional matrix adjust. Identities = 236/560 (42%), Positives = 321/560 (57%), Gaps = 46/560 (8%) Query: 252 VRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVS 311 V TRFPPEPNGYLHIGH+K+I +NFG A+ + G C LRFDDTNP KE EY ESIK V Sbjct: 28 VHTRFPPEPNGYLHIGHAKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVESIKNDVE 87 Query: 312 WLGFKPWK--ITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKEDGTPGGER 369 WLGF W + YSSDYFD+L+ A LI G AYV T E+I+ RG PG Sbjct: 88 WLGFH-WSGNVRYSSDYFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQ--PGKN- 143 Query: 370 YACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAYRVLNAPHPR 429 +RD+S+E+NL F MR G ++ G+A LR K D+ SP M D + YR+ A H + Sbjct: 144 --SPYRDRSVEENLALFEKMRAGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQ 201 Query: 430 TGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHV-FRPAQREYGR 488 TG KW IYP YDFTHC+ D++E ITHSL T EF +R Y+W+ D + + P Q E+ R Sbjct: 202 TGNKWCIYPMYDFTHCISDALEGITHSLRTLEFQDNRRLYDWVLDNITIPVHPRQYEFSR 261 Query: 489 LNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINTLGVTTSTT 548 LN+ TV+SKRK+ LV +K V GWDDPR+ T+ +RRRG +I F +GVT Sbjct: 262 LNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDN 321 Query: 549 NIQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDNLSDDYEELATIPYRPGTPEFGERTV 608 I++ ES +R+ L + PR M V+DPV++V++N + E+ T+P P PE G R V Sbjct: 322 TIEMASLESCIREDLNENAPRAMAVIDPVKLVIENYQGE-GEMVTMPNHPNKPEMGSRQV 380 Query: 609 PFTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIKVSHTVSFKSLEKDEAGKIIRIHVNY 668 PF+ + +I+R+DF E +K++ RL + V L + ++ + + +EKD G I I Y Sbjct: 381 PFSGEIWIDRADFREEA-NKQYKRLVLGKEVRL-RNAYVIKAERVEKDAEGNITTIFCTY 438 Query: 669 DNKV--EEGSKPKKPKTYIQWVPISSKYNSPLRVTETRVYNQLFKSENPSSHPEGFLKDI 726 D ++ + +K K I WV S+ + P+ E R+Y++LF NP + + FL I Sbjct: 439 DADTLSKDPADGRKVKGVIHWV--SAAHALPV---EIRLYDRLFSVPNPGA-ADDFLSVI 492 Query: 727 NPESEVVYKESVMEHNFGDVVKNSPWVVDSVKNSEFYVEEDKDSKEVCRFQAMRVGYFTL 786 NPES V+ K+ E + D V FQ R GYF L Sbjct: 493 NPESLVI-KQGFAEPSLKDAVAGKA------------------------FQFEREGYFCL 527 Query: 787 D-KESTTSKVILNRIVSLKD 805 D + ST K + NR V L+D Sbjct: 528 DSRHSTAEKPVFNRTVGLRD 547 >5BNZ-A nrPDB Length = 564 Score = 379 bits (974), Expect = e-105, Method: Compositional matrix adjust. Identities = 227/564 (40%), Positives = 318/564 (56%), Gaps = 45/564 (7%) Query: 250 GKVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRM 309 K+ TRFPPEPNGYLHIGH+K+I +NFG A+ G C+LRFDDTNP KE EY ++I+ Sbjct: 35 AKIVTRFPPEPNGYLHIGHAKSICLNFGLAQEFAGDCHLRFDDTNPAKEDQEYIDAIEAD 94 Query: 310 VSWLGFKPW--KITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKEDGTPGG 367 + WLGF+ W ++ Y+S+YFD+L+ A LIK GKA+VC EE++ RG + PG Sbjct: 95 IKWLGFQ-WSGEVCYASNYFDQLHAWAVELIKAGKAFVCDLGPEEMREYRGTLTE--PGR 151 Query: 368 ERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAYRVLNAPH 427 +RD+S+E+NL F M+ G++ G LR K D+ SP+ + D I YR+ +A H Sbjct: 152 N---SPYRDRSVEENLDLFARMKAGEFPDGARSLRAKIDMGSPNMNLRDPILYRIRHAHH 208 Query: 428 PRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHV-FRPAQREY 486 +TG KW IYP+YDFTH D++E ITHS+CT EF R YEW + V +P Q E+ Sbjct: 209 HQTGDKWCIYPSYDFTHGQSDAIEGITHSICTLEFEDHRPLYEWFLANLPVPAQPRQYEF 268 Query: 487 GRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINTLGVTTS 546 RLN+ TV SKRK+ QLVDE V GWDDPR+ TL RRRG P +I +F +GV + Sbjct: 269 SRLNLNYTVTSKRKLKQLVDEGHVSGWDDPRMSTLSGYRRRGYTPESIRNFCEMIGVNRA 328 Query: 547 TTNIQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDNLSDDYEELATIPYRPGTPEFGER 606 + + + E ++R +L+ T PR M VL P++VV+ N + E +P P + G R Sbjct: 329 SGVVDIGMLEFSIRDHLDATAPRAMCVLKPLKVVITNYPEGQVENLELPRHP-KEDMGVR 387 Query: 607 TVPFTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIKVSHTVSFKSLEKDEAGKIIRIHV 666 +PF + +I+ DF E V + RL P V L + S+ + KD G I+ + Sbjct: 388 VLPFGRELFIDAGDFEE-VPPAGYKRLIPGGEVRL-RGSYVIRADEAIKDADGNIVELRC 445 Query: 667 NYD-NKVEEGSKPKKPKTYIQWVPISSKYNSPLRVTETRVYNQLFKSENPSSHPEG--FL 723 +YD + + + + +K K I WVP E R+Y++LF+S NP EG FL Sbjct: 446 SYDPDTLGKNPEGRKVKGVIHWVPAEGSVE-----CEVRLYDRLFRSANPEKAEEGGSFL 500 Query: 724 KDINPESEVVYKESVMEHNFGDVVKNSPWVVDSVKNSEFYVEEDKDSKEVCRFQAMRVGY 783 +IN +S V E + G + +P ED RFQ R GY Sbjct: 501 DNINADSLQVLAGCRAEPSLG---QANP--------------ED-------RFQFEREGY 536 Query: 784 FTLD-KESTTSKVILNRIVSLKDA 806 F D K+S K + NR V+L+D+ Sbjct: 537 FVADLKDSRPGKPVFNRTVTLRDS 560 >3TL4-X nrPDB Length = 187 Score = 378 bits (970), Expect = e-105, Method: Compositional matrix adjust. Identities = 187/187 (100%), Positives = 187/187 (100%) Query: 1 MSSVEELTQLFSQVGFEDKKVKEIVKNKKVSDSLYKLIKETPSDYQWNKSTRALVHNLAS 60 MSSVEELTQLFSQVGFEDKKVKEIVKNKKVSDSLYKLIKETPSDYQWNKSTRALVHNLAS Sbjct: 1 MSSVEELTQLFSQVGFEDKKVKEIVKNKKVSDSLYKLIKETPSDYQWNKSTRALVHNLAS 60 Query: 61 FVKGTDLPKSELIVNGIINGDLKTSLQVDAAFKYVKANGEASTKMGMNENSGVGIEITED 120 FVKGTDLPKSELIVNGIINGDLKTSLQVDAAFKYVKANGEASTKMGMNENSGVGIEITED Sbjct: 61 FVKGTDLPKSELIVNGIINGDLKTSLQVDAAFKYVKANGEASTKMGMNENSGVGIEITED 120 Query: 121 QVRNYVMQYIQENKERILTERYKLVPGIFADVKNLKELKWADPRSFKPIIDQEVLKLLGP 180 QVRNYVMQYIQENKERILTERYKLVPGIFADVKNLKELKWADPRSFKPIIDQEVLKLLGP Sbjct: 121 QVRNYVMQYIQENKERILTERYKLVPGIFADVKNLKELKWADPRSFKPIIDQEVLKLLGP 180 Query: 181 KDERDLI 187 KDERDLI Sbjct: 181 KDERDLI 187 >4P2B-A nrPDB Length = 576 Score = 365 bits (937), Expect = e-101, Method: Compositional matrix adjust. Identities = 211/494 (42%), Positives = 283/494 (57%), Gaps = 24/494 (4%) Query: 252 VRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVS 311 V TRFPPEPNG+LH+GH+K++ +NFG AK G C+LRFDDTNP KE Y ESI+R V Sbjct: 41 VITRFPPEPNGFLHLGHAKSVCLNFGLAKAFGGRCHLRFDDTNPMKEETRYIESIQRDVR 100 Query: 312 WLGFKPW--KITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKEDGTPGGER 369 WLG W + Y+SDYF +LY AE+LIK G A+V + EEI+R RG PG Sbjct: 101 WLG-GDWGNHLYYASDYFQQLYDWAELLIKKGLAFVDDDSLEEIRRKRG--SISQPGEN- 156 Query: 370 YACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAYRVLNAPHPR 429 R++SIE+NL FR MR G+++ G +LR K D+ + M D + YR+L HPR Sbjct: 157 --SPFRERSIEENLDLFRRMRAGEFEEGSRVLRAKIDMTHSNMNMRDPVLYRILKKEHPR 214 Query: 430 TGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHVFRPAQREYGRL 489 TG +W IYP YD+ H DS+ENITHS+CT EF L R Y+W +++ + R Q E+ RL Sbjct: 215 TGNQWVIYPMYDYAHGQSDSIENITHSICTLEFDLHRILYDWFQEKLEITRTRQIEFARL 274 Query: 490 NITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINTLGVTTSTTN 549 N+T TV+SKRK+ LV EK+V GWDDPRL TL +RRRGVPP A+ F + +GV + Sbjct: 275 NVTYTVMSKRKLLALVTEKWVDGWDDPRLPTLSGLRRRGVPPSALRDFCDKVGVARREST 334 Query: 550 IQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDNLSDDYEELATIPYRPGTPEFGERTVP 609 I+V E +R L R + DP+ V + N D E + T P FG R + Sbjct: 335 IKVEVLEKCIRDALHVVAHRRFAIQDPIAVTITNYGDKVETI-TAANHPEDESFGTRELH 393 Query: 610 FTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIKVSHTVSFKSLEKDEAGKIIRIHVNYD 669 F+ K YI+R DF EN + RL P V L K ++ + + KD +G + + YD Sbjct: 394 FSKKLYIDRDDFMEN-PPAGYRRLAPGAEVRL-KHAYWIKCVDVVKDASGLVTELLCTYD 451 Query: 670 NKVEEGS---KPKKPKTYIQWVPISSKYNSPLRVTETRVYNQLFKSENPSSHPE-----G 721 + + S +K K I W +S K P E R++ +LF NP E Sbjct: 452 PQTKNCSVAPDGRKVKGAIHW--LSEKDAVP---AEIRIFGRLFTKPNPEEEDESNPNAS 506 Query: 722 FLKDINPESEVVYK 735 + ++IN ES VYK Sbjct: 507 WRENINKESLKVYK 520 >5ZDO-A nrPDB Length = 548 Score = 358 bits (918), Expect = 6e-99, Method: Compositional matrix adjust. Identities = 223/569 (39%), Positives = 328/569 (57%), Gaps = 58/569 (10%) Query: 250 GKVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRM 309 K+ TRFPPEPNGYLHIGH+++I++NFG A+ + G C LRFDDTNPE E EY +I+ Sbjct: 23 AKLVTRFPPEPNGYLHIGHARSIVLNFGLAQDYGGECNLRFDDTNPETEKEEYARAIEED 82 Query: 310 VSWLGFKPWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKEDGTPGGER 369 V WLGF+P ++ Y+SDYF+ +Y+ A VLI+ GKAYV EE+ ++ G P Sbjct: 83 VRWLGFRPTRVLYASDYFETMYQCALVLIQEGKAYVDDLPEEEMSE---LRAQGKP---- 135 Query: 370 YACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAYRVLNAPHPR 429 +R++S+E+NL+ F MR G++ G +LR K D P+ ++ D + YR+++APH Sbjct: 136 --SPYRERSVEENLELFERMRRGEFPTGSRVLRAKIDPAHPNFKLRDPVLYRIVHAPHYH 193 Query: 430 TGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWL-------CDQVHVFRPA 482 G +W IYP YDF H L D +E +THSLCT EF +R Y+W+ C RP Sbjct: 194 VGDRWVIYPMYDFAHPLEDFIEGVTHSLCTLEFENNRTVYDWVIENLKGKCGLPTSPRPH 253 Query: 483 QREYGRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINTLG 542 Q E+ RL+++ TVLSKRK+ +LV+ +V GWDDPRL TL +RRRGV P AI+ F+ G Sbjct: 254 QYEFARLDLSHTVLSKRKLIKLVEGGYVSGWDDPRLPTLRGLRRRGVRPEAIVEFVRKTG 313 Query: 543 VTTSTTNIQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDNLSDDYEELATIPYRP-GTP 601 ++ + I++ FE VR L PR++ V+DP++VV+ N EE PY P P Sbjct: 314 ISRNEAQIEMDLFEEVVRDDLNPIAPRVLGVVDPLKVVLTNYEG--EEWIEAPYWPRDIP 371 Query: 602 EFGERTVPFTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIKVSHTVSFKSLEKDEAGKI 661 + G R +PF+ + YIER+DFS N K + RL P Q +++ H + + E G Sbjct: 372 KEGTRPLPFSPELYIERTDFSLN-PPKGWKRLAPGQ---RVRLRHAYVIELEDVVEEGGE 427 Query: 662 IRIHVNYDNKVEEGSKPK---KPKTYIQWVPISSKYNSPLRVTETRVYNQLFKSENPSSH 718 +R+ G+ P+ +PK I WV S+++ P+ E R+Y +LF++++P Sbjct: 428 VRLLKARIVPGTLGANPEDGVRPKGVIHWV--SARHALPV---EFRLYGRLFRTKDPEEG 482 Query: 719 PEGFLKDINPESEVVYKESVMEHNFGDVVKNSPWVVDSVKNSEFYVEEDKDSKEVCRFQA 778 + FL+++NPE+ VV K +E + V P E R+Q Sbjct: 483 GD-FLQNLNPEALVV-KRGFIEPS----VAQDP--------------------EDTRYQL 516 Query: 779 MRVGYFTLDK-ESTTSKVILNRIVSLKDA 806 R+GYF D +S +++NRIV LK+ Sbjct: 517 ERLGYFWRDPVDSRPEALVMNRIVPLKEG 545 >2HZ7-A nrPDB Length = 851 Score = 337 bits (863), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 220/597 (36%), Positives = 309/597 (51%), Gaps = 67/597 (11%) Query: 251 KVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMV 310 +V TRFPP+P+GY H+GH A +++F A+ + G LR DDTNPE EY +SI + Sbjct: 66 RVVTRFPPDPSGYAHLGHVFASLLDFNTARQYGGQFNLRMDDTNPELARQEYVDSIADDL 125 Query: 311 SWLGFKPW--KITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRG-IKEDGTPGG 367 WLG W Y+SDYFD Y AE LI+ G AYV + EE+ R RG GTP Sbjct: 126 KWLGLD-WGEHFYYASDYFDRYYAYAEQLIRQGDAYVESVSPEELSRLRGNATTPGTP-- 182 Query: 368 ERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAYRVLNAPH 427 +RD+S+E+NL R M+ G++ GE +LR K DL +P+ ++ D + YR++N PH Sbjct: 183 ----SPYRDRSVEENLDLLRRMKAGEFADGEHVLRAKIDLTAPNMKLRDPVLYRIVNKPH 238 Query: 428 PRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHV-FRPAQREY 486 RT +W IYP YDF H L D++E +THS+C+ EF +R Y+WL ++++ RP Q E+ Sbjct: 239 FRTSDEWHIYPAYDFEHPLQDAIEGVTHSMCSLEFVDNRAIYDWLMEKLNFDPRPHQYEF 298 Query: 487 GRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINTLGVTTS 546 GR + T+ SKRK+ +LV V GWDDPR+ TL A RR GV P A+ +F +GV+ + Sbjct: 299 GRRGLEYTITSKRKLRELVQAGRVSGWDDPRMPTLRAQRRLGVTPEAVRAFAAQIGVSRT 358 Query: 547 TTNIQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDNLSDDYEELATIPYRP-------- 598 + + +E+AVR L PR+M VLDPV+V + NL D E+ ++PY P Sbjct: 359 NRTVDIAVYENAVRDDLNHRAPRVMAVLDPVKVTLTNL--DGEKTLSLPYWPHDVVRDSP 416 Query: 599 ----GTPEFGE-------RTVPFTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIKVSHT 647 G P G R VP T + YIER DFS K F RLTP V L + + Sbjct: 417 DGLVGMPGGGRVAPEEAVRDVPLTRELYIERDDFSP-APPKGFKRLTPGGTVRL-RGAGI 474 Query: 648 VSFKSLEKDEAGKIIRIHVNYDNKVEEGSKPKKPKTYIQWVPISSKYNSPLRVTETRVYN 707 + DEAG++ I + K I WV S++ P E R+Y+ Sbjct: 475 IRADDFGTDEAGQVTHIRATLLG------EDAKAAGVIHWV--SAERALP---AEFRLYD 523 Query: 708 QLFKSENPSSHPEGFLKDINPESEVVYKESVMEHNFGDVVKNSP--------WVVDSVKN 759 +LF+ HPEG D+ +S + E G + +P DS++ Sbjct: 524 RLFR----VPHPEGENADVEDDSA---GPAEHEAEPGAGQETAPVSQGFMRYLTPDSLRV 576 Query: 760 SEFYVEEDKDSKEV-CRFQAMRVGYFTLDK------ESTTSKVILNRIVSLKDATSK 809 YVE R+Q R GYF D +S ++ RI++LKD K Sbjct: 577 LRGYVEPSVAGDPADTRYQFERQGYFWRDPVELERVDSREDALVFGRIITLKDTWGK 633 >3AII-A nrPDB Length = 553 Score = 223 bits (569), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 129/375 (34%), Positives = 190/375 (50%), Gaps = 13/375 (3%) Query: 250 GKVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRM 309 G+V RF P P+G LHIGH++A ++N YA+ ++G LR +DT+P + PE ++ I Sbjct: 95 GEVVLRFAPNPSGPLHIGHARAAILNHEYARKYDGRLILRIEDTDPRRVDPEAYDMIPAD 154 Query: 310 VSWLGFKPWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKEDGTPGGER 369 + WLG + + SD + Y E LI+ G AYVC C EE R +K G Sbjct: 155 LEWLGVEWDETVIQSDRMETYYEYTEKLIERGGAYVCTCRPEEF---RELKNRGE----- 206 Query: 370 YACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAYRVLNAPHPR 429 AC R +NLQ +R+M + K G A++R+K DLN P+P + D ++ R++ A HPR Sbjct: 207 -ACHCRSLGFRENLQRWREMFE--MKEGSAVVRVKTDLNHPNPAIRDWVSMRIVEAEHPR 263 Query: 430 TGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHVFRPAQREYGRL 489 TGT++R+YP +F+ + D + +TH L + +RE E+L + P YGRL Sbjct: 264 TGTRYRVYPMMNFSVAVDDHLLGVTHVLRGKDHLANREKQEYLYRHLGWEPPEFIHYGRL 323 Query: 490 NITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINTLGVTTSTTN 549 + LS + + GWDDPRL TL AI RRG+ P AI + +GV + + Sbjct: 324 KMDDVALSTSGAREGILRGEYSGWDDPRLGTLRAIARRGIRPEAIRKLMVEIGVKIADST 383 Query: 550 IQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDNLSDDYEELATIPYRPGTPEFGERTVP 609 + + R LE+ R F DPV++ V L P P PE G R + Sbjct: 384 MSWKKIYGLNRSILEEEARRYFFAADPVKLEVVGLPGPVR--VERPLHPDHPEIGNRVLE 441 Query: 610 FTNKFYIERSDFSEN 624 + Y+ D E Sbjct: 442 LRGEVYLPGDDLGEG 456 >2CFO-A nrPDB Length = 492 Score = 85.5 bits (210), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 50/134 (37%), Positives = 72/134 (53%), Gaps = 6/134 (4%) Query: 252 VRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVS 311 VR R P P G LHIG ++ + N+ YA++ G LR +DT+ E+ PEY E+I + Sbjct: 2 VRVRLAPSPTGNLHIGTARTAVFNWLYARHRGGKFILRIEDTDRERSRPEYTENILEGLQ 61 Query: 312 WLGFKPWKIT--YSSDYFDELYRLA-EVLIKNGKAYVCHCTAEEIKRGRGIKEDGTPGGE 368 WLG W + SD D LYR A + L+ G AY C+CT EE++ R ++ Sbjct: 62 WLGLT-WDEGPYFQSDRLD-LYRQAIQTLLDKGLAYYCYCTPEELEALRA-EQKAKGQAP 118 Query: 369 RYACKHRDQSIEQN 382 RY +HR + E+ Sbjct: 119 RYDNRHRHLTPEEQ 132 >2O5R-A nrPDB Length = 481 Score = 70.9 bits (172), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 42/116 (36%), Positives = 58/116 (50%), Gaps = 11/116 (9%) Query: 252 VRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVS 311 VR RF P P G+LH+G ++ + NF +A+ G LR +DT+ E+ EY E + + Sbjct: 14 VRVRFAPSPTGFLHVGGARTALFNFLFARKEKGKFILRIEDTDLERSEREYEEKLMESLR 73 Query: 312 WLGFKPW---------KITYSSDYFDELYR-LAEVLIKNGKAYVCHCTAEEIKRGR 357 WLG W Y E+YR AE L+K GKAY + EEI+ R Sbjct: 74 WLGLL-WDEGPDVGGDHGPYRQSERVEIYREHAERLVKEGKAYYVYAYPEEIEEMR 128 >4GRI-A nrPDB Length = 512 Score = 69.3 bits (168), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 60/229 (26%), Positives = 101/229 (44%), Gaps = 34/229 (14%) Query: 253 RTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVSW 312 R R+ P P G HIG + + N+ +AK G LR +DT+ + +PE + + W Sbjct: 26 RVRYAPSPTGLQHIGGIRTALFNYFFAKSCGGKFLLRIEDTDQSRYSPEAENDLYSSLKW 85 Query: 313 LG------------FKPWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIK 360 LG + P+ + S + + A+ LI++G AY C+C+ E ++R + I+ Sbjct: 86 LGISFDEGPVVGGDYAPYVQSQRSAIYKQ---YAKYLIESGHAYYCYCSPERLERIKKIQ 142 Query: 361 EDGT--PGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLI 418 PG +R+ ++ +E L + K KP ++R K L + D++ Sbjct: 143 NINKMPPGYDRHCRNLSNEEVENALIK-------KIKP---VVRFKIPLEGDT-SFDDIL 191 Query: 419 AYRVLNA-----PHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEF 462 R+ A P P K PTY + + D + ITH L E+ Sbjct: 192 LGRITWANKDISPDPVI-LKSDGLPTYHLANVVDDYLMKITHVLRAQEW 239 >3AL0-C nrPDB Length = 592 Score = 68.6 bits (166), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 67/246 (27%), Positives = 113/246 (45%), Gaps = 49/246 (19%) Query: 115 IEITEDQVRNYVMQYIQENKERILTERYKLVPGI---FADVKNLKELKWADPRSFKPIID 171 +E++EDQ R +M+ QE + + V G+ + V++ +L+ DPR F Sbjct: 19 LELSEDQ-RESLMKDFQEILDYVELLNEVDVEGVEPMYTPVEDSAKLRKGDPRFF----- 72 Query: 172 QEVLKLLGPKDERDLIKKKTKNNEKKKTNSAKKSSDNSASSGPKRTMFNEGFLGDLHKVG 231 + RDLIKK N ++K K + S +MF G D+ +VG Sbjct: 73 ----------EMRDLIKK---NFPEEKDGHIKVPGIHRGSGSGSGSMFITGAFFDILEVG 119 Query: 232 ENPQAYPELMKEHLEVTGGKVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFD 291 P+ ++ E+ VR RF P P G+LH+G ++ + N+ +A+ G LR + Sbjct: 120 ------PKKIRRCFEL----VRVRFAPSPTGHLHVGGARTALFNWMFARKEGGKFILRIE 169 Query: 292 DTNPEKEAPEYFESIKRMVSWLG------------FKPWKITYSSDYFDELYR-LAEVLI 338 DT+ E+ + EY + I + W G F P++ + E+YR AE L+ Sbjct: 170 DTDTERSSREYEQQILESLRWCGLDWDEGPDIGGDFGPYRQSERL----EIYREYAEKLV 225 Query: 339 KNGKAY 344 ++ +AY Sbjct: 226 EDKRAY 231 >6B1P-A nrPDB Length = 471 Score = 67.8 bits (164), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 38/128 (29%), Positives = 66/128 (51%), Gaps = 6/128 (4%) Query: 252 VRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVS 311 + TRF P P GYLHIG + + N+ +A+ + G +LR +DT+ + + E +I Sbjct: 12 IVTRFAPSPTGYLHIGGLRTAIFNYLFARANQGKFFLRIEDTDLSRNSIEAANAIIEAFK 71 Query: 312 WLGFK-PWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKEDGTPGGE-- 368 W+G + +I Y S F+ + L+ KAY C+ + +E+ ++E+ E Sbjct: 72 WVGLEYDGEILYQSKRFEIYKEYIQKLLDEDKAYYCYMSKDELD---ALREEQKARKETP 128 Query: 369 RYACKHRD 376 RY ++RD Sbjct: 129 RYDNRYRD 136 >6BRL-A nrPDB Length = 511 Score = 64.3 bits (155), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 74/335 (22%), Positives = 142/335 (42%), Gaps = 34/335 (10%) Query: 251 KVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMV 310 KVR RF P P G LH+G + + ++ +AK++ G LR +DT+ ++ P E I + Sbjct: 11 KVRVRFAPSPTGPLHLGGVRTALYDYLFAKHNGGDFILRIEDTDTQRYVPGSEEYIMEAL 70 Query: 311 SWLG------------FKPWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRG 358 W+G + P++ + D +D R E ++K AY+ T EE+ + Sbjct: 71 EWIGMVPDESPKHGGPYAPYRQSERRDIYD---RYTEQILKTDYAYLAFDTPEELDQ--- 124 Query: 359 IKEDGTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEA--ILRMKQDLNSPSPQMWD 416 I+ + G+ +A + ++ +N + K + ++R K L+ + D Sbjct: 125 IRAEFEARGDVFAYNYETRNRLRNSISLPEEEVKKLLEEKTPYVIRFKMPLDR-IINLND 183 Query: 417 LIAYRV---LNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLC 473 +I + N + K PTY F + + D ITH + E+ S + L Sbjct: 184 IIRGKFSVNTNTLDDKVLVKNDGMPTYHFANIIDDHEMKITHVIRGEEWLPSMALHVLLY 243 Query: 474 DQVHVFRPAQREYGRLNITGTVLSKRKIAQLVDEKF------VRGWDDPRLFTLEAIRRR 527 + + P E+ L++ K K+++ +KF + D T R Sbjct: 244 EAMGWDAP---EFAHLSLILKPEGKGKLSKRDGDKFGFPVFPLNFTDSATGNTSAGYREE 300 Query: 528 GVPPGAILSFINTLGVTTSTTNIQVVRFESAVRKY 562 G P A ++ + LG + + N ++V + ++++ Sbjct: 301 GYLPEAFINMVAMLGWSPA-DNKEIVSMDEMIKEF 334 >4G6Z-A nrPDB Length = 490 Score = 63.5 bits (153), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 34/122 (27%), Positives = 62/122 (50%), Gaps = 10/122 (8%) Query: 252 VRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVS 311 VRTRF P P G++H+G+ ++ + + +A+ GT LR +DT+ E+ + E ++I ++ Sbjct: 26 VRTRFAPSPTGFIHLGNIRSALYPWAFARKMKGTFVLRIEDTDVERSSQEAVDAILEGMA 85 Query: 312 WLGFK----PWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKEDGTPGG 367 WLG P+ Y D + + + G Y C+ + EE+ ++E G Sbjct: 86 WLGLDYDEGPY---YQMQRMDRYREVLAQMQEKGLVYPCYMSTEELD---ALRERQRAAG 139 Query: 368 ER 369 E+ Sbjct: 140 EK 141 >5H4V-A nrPDB Length = 488 Score = 62.4 bits (150), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 35/109 (32%), Positives = 52/109 (47%), Gaps = 7/109 (6%) Query: 253 RTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVSW 312 RTRF P P GYLHIG ++ + + A+ G LR +DT+ ++ ++I + W Sbjct: 25 RTRFAPSPTGYLHIGGARTALYCWLEARRRGGQFVLRIEDTDRQRSTQAAIDAILEAMQW 84 Query: 313 LGF----KPWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGR 357 LG P Y + +AE L+ GKAY + T EE+ R Sbjct: 85 LGLGYDEGP---IYQTQRVARYQEVAEQLLAQGKAYYAYETREELDAMR 130 >5TGT-A nrPDB Length = 502 Score = 60.8 bits (146), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 73/310 (23%), Positives = 116/310 (37%), Gaps = 50/310 (16%) Query: 252 VRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVS 311 VRTR P P G H+G + + N +A+ H G LR +DT+ + E + I + Sbjct: 12 VRTRIAPSPTGDPHVGTAYIALFNLCFARQHGGQFILRIEDTDQLRSTRESEQQIYDALR 71 Query: 312 WLGFKPW---------KITYSSDYFDELY-RLAEVLIKNGKAYVCHCTAEEIK--RGRGI 359 WLG + W Y +Y + ++ L++ G A+ C CT E + R + Sbjct: 72 WLGIE-WDEGPDVGGPHGPYRQSERGHIYKKYSDELVEKGHAFTCFCTPERLDAVRAEQM 130 Query: 360 KEDGTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIA 419 TP + + +++ L P E + + L WD + Sbjct: 131 ARKETPRYDGHCMHLPKDEVQRRLAAGESHVTRMKVPTEGVCVVPDMLRGDVEIPWDRMD 190 Query: 420 YRVLNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSR-------ESYEWL 472 +VL K PTY + + D + ITH L E+ S E + W Sbjct: 191 MQVL--------MKADGLPTYFLANVVDDHLMGITHVLRGEEWLPSAPKLIKLYEYFGWE 242 Query: 473 CDQVHVFRPAQREYGRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPG 532 Q+ + P R N + LSKRK +P T R G P Sbjct: 243 QPQL-CYMPLLR-----NPDKSKLSKRK--------------NPTSITF--YERMGYLPQ 280 Query: 533 AILSFINTLG 542 A+L+++ +G Sbjct: 281 ALLNYLGRMG 290 >3AKZ-B nrPDB Length = 487 Score = 60.1 bits (144), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 41/140 (29%), Positives = 69/140 (49%), Gaps = 27/140 (19%) Query: 218 MFNEGFLGDLHKVGENPQAYPELMKEHLEVTGGKVRTRFPPEPNGYLHIGHSKAIMVNFG 277 MF G D+ +VG P+ ++ E+ VR RF P P G+LH+G ++ + N+ Sbjct: 1 MFITGAFFDILEVG------PKKIRRCFEL----VRVRFAPSPTGHLHVGGARTALFNWM 50 Query: 278 YAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVSWLG------------FKPWKITYSSD 325 +A+ G LR +DT+ E+ + EY + I + W G F P++ + Sbjct: 51 FARKEGGKFILRIEDTDTERSSREYEQQILESLRWCGLDWDEGPDIGGDFGPYRQSERL- 109 Query: 326 YFDELYR-LAEVLIKNGKAY 344 E+YR AE L+++ +AY Sbjct: 110 ---EIYREYAEKLVEDKRAY 126 >2JA2-A nrPDB Length = 498 Score = 59.7 bits (143), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 33/116 (28%), Positives = 59/116 (50%), Gaps = 17/116 (14%) Query: 252 VRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVS 311 VR RF P P G H+G + + N+ YA++ GT R +DT+ ++++ E + ++ + Sbjct: 7 VRVRFCPSPTGTPHVGLVRTALFNWAYARHTGGTFVFRIEDTDAQRDSEESYLALLDALR 66 Query: 312 WLG------------FKPWKITYSSD-YFDELYRLAEVLIKNGKAYVCHCTAEEIK 354 WLG + P++ + ++ Y D L R L+ G+AY T EE++ Sbjct: 67 WLGLDWDEGPEVGGPYGPYRQSQRAEIYRDVLAR----LLAAGEAYHAFSTPEEVE 118 >4A91-A nrPDB Length = 298 Score = 53.1 bits (126), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 32/107 (29%), Positives = 48/107 (44%), Gaps = 3/107 (2%) Query: 255 RFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVSWLG 314 RF P P+G LH G A + ++ A+ G +R +D +P +E P E+I R + G Sbjct: 9 RFAPSPSGELHFGSLIAALGSYLQARARQGRWLVRIEDIDPPREVPGAAETILRQLEHYG 68 Query: 315 FKPW--KITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGI 359 W + + S D L + G +Y C CT I+ GI Sbjct: 69 LH-WDGDVLWQSQRHDAYREALAWLHEQGLSYYCTCTRARIQSIGGI 114 >2CV2-A nrPDB Length = 468 Score = 50.4 bits (119), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 36/121 (29%), Positives = 54/121 (44%), Gaps = 11/121 (9%) Query: 252 VRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVS 311 V TR P P G H+G + + N+ +A+ + G +R +DT+ + P E I + Sbjct: 2 VVTRIAPSPTGDPHVGTAYIALFNYAWARRNGGRFIVRIEDTDRARYVPGAEERILAALK 61 Query: 312 WLGFK---------PWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKED 362 WLG P S+ + AE L+K G AY T EE+++ R KE Sbjct: 62 WLGLSYDEGPDVGGPHGPYRQSERLPLYQKYAEELLKRGWAYRAFETPEELEQIR--KEK 119 Query: 363 G 363 G Sbjct: 120 G 120 >3DFY-A nrPDB Length = 345 Score = 33.5 bits (75), Expect = 0.42, Method: Compositional matrix adjust. Identities = 51/193 (26%), Positives = 79/193 (40%), Gaps = 29/193 (15%) Query: 95 VKANGEASTKMGMNENSGVGIEITEDQVRNYVMQYIQENKERI--LTERYKLVPGIFADV 152 VK GEAS +N + E+ VR + N RI +T+R P + A V Sbjct: 43 VKGYGEASPSFRVNGERVEALLAIENAVREMITGIDVRNYARIFEITDRLFGFPSLKAAV 102 Query: 153 KNLKELKWADPRSFKPIIDQEVLKLLGPK-DERDLIKKKTKNNEKKKTNSAKKSSDNSAS 211 + +A + + +V LLG K DE + K + + + AKK Sbjct: 103 Q------FATLDALSQELGTQVCYLLGGKRDEIETDKTVGIDTVENRVKEAKK------- 149 Query: 212 SGPKRTMFNEGFLGDLHKVGENPQAYPELMKEHLEVTGGKVRTRFPPEPNGYLHIGHSKA 271 +F EGF KVGEN + E ++E +VT G ++ + N +G+++ Sbjct: 150 ------IFEEGFRVIKIKVGENLKEDIEAVEEIAKVTRG---AKYIVDAN----MGYTQK 196 Query: 272 IMVNFGYAKYHNG 284 V F A Y G Sbjct: 197 EAVEFARAVYQKG 209 >6CE1-A nrPDB Length = 686 Score = 30.4 bits (67), Expect = 2.9, Method: Compositional matrix adjust. Identities = 29/110 (26%), Positives = 46/110 (41%), Gaps = 3/110 (2%) Query: 322 YSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKEDGTPGGERYACKHRDQSIEQ 381 Y F L R+ V +++ + VC E + G +GT E Y D I Sbjct: 17 YKKAGFMSLQRIVRVSLEHPTSAVCVAGVETLVDIYGSVPEGTEMFEVYGTPGVDIYISP 76 Query: 382 NLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWD---LIAYRVLNAPHP 428 N++ R+ D + +A L + +NSPS + D I+Y + P P Sbjct: 77 NMERGRERADTRRWRFDATLEIIVVMNSPSNDLNDSHVQISYHSSHEPLP 126 >5AEG-A nrPDB Length = 686 Score = 29.6 bits (65), Expect = 4.9, Method: Compositional matrix adjust. Identities = 35/145 (24%), Positives = 58/145 (40%), Gaps = 26/145 (17%) Query: 230 VGENPQAYPELMKEHLEVTGGKVRTRFPPEPNG------YLHIGHSKAIMVNFGYAKYHN 283 VG N Q Y + E GG F P+P Y H+ +S + +F +YH Sbjct: 155 VGRNKQTYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHE 214 Query: 284 GTCY-----LRFDDTNPEKEAPEYFESIKRMVSWLGFKPWKITYSSDYFDELYRLAEVLI 338 + LRF+ A Y ++++ + LG +P + D +Y + I Sbjct: 215 LALWEDKATLRFE------CADTYISLLEKLTALLGRQP-------ELPDWIYDGVTLGI 261 Query: 339 KNGKAYVCHCTAEEIKRGRGIKEDG 363 + G VC + + R G+K +G Sbjct: 262 QGGTE-VCQKKLDTM-RNAGVKVNG 284 >3CEI-A nrPDB Length = 213 Score = 29.3 bits (64), Expect = 6.3, Method: Compositional matrix adjust. Identities = 14/43 (32%), Positives = 21/43 (48%) Query: 32 DSLYKLIKETPSDYQWNKSTRALVHNLASFVKGTDLPKSELIV 74 DS+ + D+ K + V+NL + +KGTD KS L Sbjct: 12 DSMGDFLSPVAFDFHHGKHHQTYVNNLNNLIKGTDFEKSSLFA 54 >2QUB-A nrPDB Length = 615 Score = 29.3 bits (64), Expect = 6.6, Method: Compositional matrix adjust. Identities = 31/140 (22%), Positives = 62/140 (44%), Gaps = 19/140 (13%) Query: 640 GLIKVSHTVSFKSLEKDEAGKIIRIHVNYDN----KVEEGSKPKKPKTYIQWVPISSKYN 695 G S+ V+F S + EAG + I++ Y+N + +G+ P + P +S N Sbjct: 228 GFYAQSNYVAFASPTQYEAGGKV-INIGYENDPVFRALDGTSLTLPSLGVHDAPHTSATN 286 Query: 696 SPLRVTE---TRVYNQL---------FKSENPSSHPEGFLKDINPE--SEVVYKESVMEH 741 + + + + +N L + S P + +G ++ +N E S +++ Sbjct: 287 NIVNFNDHYASDAWNLLPFSILNIPTWLSHLPFFYQDGLMRVLNSEFYSLTDKDSTIIVS 346 Query: 742 NFGDVVKNSPWVVDSVKNSE 761 N +V + + WV D +N+E Sbjct: 347 NLSNVTRGNTWVEDLNRNAE 366 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4H3S-A nrPDB 1171 0.0 4R3Z-C nrPDB 1019 0.0 5BNZ-A nrPDB 712 0.0 2RD2-A nrPDB 694 0.0 2HZ7-A nrPDB 657 0.0 4P2B-A nrPDB 641 0.0 5ZDO-A nrPDB 627 e-180 3AII-A nrPDB 458 e-129 6BRL-A nrPDB 332 5e-91 3AL0-C nrPDB 316 2e-86 5TGT-A nrPDB 300 2e-81 3TL4-X nrPDB 299 5e-81 4GRI-A nrPDB 271 7e-73 2CFO-A nrPDB 248 7e-66 2CV2-A nrPDB 247 1e-65 6B1P-A nrPDB 236 4e-62 5H4V-A nrPDB 235 7e-62 3AKZ-B nrPDB 233 2e-61 2O5R-A nrPDB 233 2e-61 4G6Z-A nrPDB 227 2e-59 2JA2-A nrPDB 210 2e-54 4A91-A nrPDB 174 1e-43 Sequences not found previously or not previously below threshold: 2G36-A nrPDB 37 0.022 3FNR-A nrPDB 37 0.045 1IQ0-A nrPDB 36 0.057 4ARC-A nrPDB 35 0.13 5AH5-A nrPDB 34 0.18 3GWQ-A nrPDB 33 0.40 3JXE-A nrPDB 33 0.49 2ZUE-A nrPDB 32 0.92 3L9X-A nrPDB 32 1.5 5JVL-A nrPDB 31 1.9 3DFY-A nrPDB 31 2.6 1CT9-A nrPDB 31 3.1 4QRE-A nrPDB 30 3.8 CONVERGED! >4H3S-A nrPDB Length = 817 Score = 1171 bits (3028), Expect = 0.0, Method: Composition-based stats. Identities = 809/809 (100%), Positives = 809/809 (100%) Query: 1 MSSVEELTQLFSQVGFEDKKVKEIVKNKKVSDSLYKLIKETPSDYQWNKSTRALVHNLAS 60 MSSVEELTQLFSQVGFEDKKVKEIVKNKKVSDSLYKLIKETPSDYQWNKSTRALVHNLAS Sbjct: 1 MSSVEELTQLFSQVGFEDKKVKEIVKNKKVSDSLYKLIKETPSDYQWNKSTRALVHNLAS 60 Query: 61 FVKGTDLPKSELIVNGIINGDLKTSLQVDAAFKYVKANGEASTKMGMNENSGVGIEITED 120 FVKGTDLPKSELIVNGIINGDLKTSLQVDAAFKYVKANGEASTKMGMNENSGVGIEITED Sbjct: 61 FVKGTDLPKSELIVNGIINGDLKTSLQVDAAFKYVKANGEASTKMGMNENSGVGIEITED 120 Query: 121 QVRNYVMQYIQENKERILTERYKLVPGIFADVKNLKELKWADPRSFKPIIDQEVLKLLGP 180 QVRNYVMQYIQENKERILTERYKLVPGIFADVKNLKELKWADPRSFKPIIDQEVLKLLGP Sbjct: 121 QVRNYVMQYIQENKERILTERYKLVPGIFADVKNLKELKWADPRSFKPIIDQEVLKLLGP 180 Query: 181 KDERDLIKKKTKNNEKKKTNSAKKSSDNSASSGPKRTMFNEGFLGDLHKVGENPQAYPEL 240 KDERDLIKKKTKNNEKKKTNSAKKSSDNSASSGPKRTMFNEGFLGDLHKVGENPQAYPEL Sbjct: 181 KDERDLIKKKTKNNEKKKTNSAKKSSDNSASSGPKRTMFNEGFLGDLHKVGENPQAYPEL 240 Query: 241 MKEHLEVTGGKVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAP 300 MKEHLEVTGGKVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAP Sbjct: 241 MKEHLEVTGGKVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAP 300 Query: 301 EYFESIKRMVSWLGFKPWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIK 360 EYFESIKRMVSWLGFKPWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIK Sbjct: 301 EYFESIKRMVSWLGFKPWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIK 360 Query: 361 EDGTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAY 420 EDGTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAY Sbjct: 361 EDGTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAY 420 Query: 421 RVLNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHVFR 480 RVLNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHVFR Sbjct: 421 RVLNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHVFR 480 Query: 481 PAQREYGRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINT 540 PAQREYGRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINT Sbjct: 481 PAQREYGRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINT 540 Query: 541 LGVTTSTTNIQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDNLSDDYEELATIPYRPGT 600 LGVTTSTTNIQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDNLSDDYEELATIPYRPGT Sbjct: 541 LGVTTSTTNIQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDNLSDDYEELATIPYRPGT 600 Query: 601 PEFGERTVPFTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIKVSHTVSFKSLEKDEAGK 660 PEFGERTVPFTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIKVSHTVSFKSLEKDEAGK Sbjct: 601 PEFGERTVPFTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIKVSHTVSFKSLEKDEAGK 660 Query: 661 IIRIHVNYDNKVEEGSKPKKPKTYIQWVPISSKYNSPLRVTETRVYNQLFKSENPSSHPE 720 IIRIHVNYDNKVEEGSKPKKPKTYIQWVPISSKYNSPLRVTETRVYNQLFKSENPSSHPE Sbjct: 661 IIRIHVNYDNKVEEGSKPKKPKTYIQWVPISSKYNSPLRVTETRVYNQLFKSENPSSHPE 720 Query: 721 GFLKDINPESEVVYKESVMEHNFGDVVKNSPWVVDSVKNSEFYVEEDKDSKEVCRFQAMR 780 GFLKDINPESEVVYKESVMEHNFGDVVKNSPWVVDSVKNSEFYVEEDKDSKEVCRFQAMR Sbjct: 721 GFLKDINPESEVVYKESVMEHNFGDVVKNSPWVVDSVKNSEFYVEEDKDSKEVCRFQAMR 780 Query: 781 VGYFTLDKESTTSKVILNRIVSLKDATSK 809 VGYFTLDKESTTSKVILNRIVSLKDATSK Sbjct: 781 VGYFTLDKESTTSKVILNRIVSLKDATSK 809 >4R3Z-C nrPDB Length = 799 Score = 1019 bits (2635), Expect = 0.0, Method: Composition-based stats. Identities = 320/829 (38%), Positives = 452/829 (54%), Gaps = 75/829 (9%) Query: 1 MSSVEELTQLFSQVGFEDKKVKEIVKNKKVSDSLYKLIKETPSDY--QWNKSTRALVHNL 58 M++++ L+ LF+ +G ++K +E +KN +S L + + +K+T L++ L Sbjct: 25 MAALDSLS-LFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGL 83 Query: 59 ASFVKGTDLPKSELIVNGIINGDLKTSLQVDAAFKYVKANG-EASTKMGMNENSGVGIEI 117 AS ++ D + +V+ I + + T Q+ AA +YV+++ + + GVG+ + Sbjct: 84 ASRLR--DTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIV 141 Query: 118 TEDQVRNYVMQYIQENKERILTERYKLVPGIFADVKNLKELKWADPRSFKPIIDQEVLKL 177 T +Q+ V I ++ ++L ERY G+ + LKWAD + K +D +VL L Sbjct: 142 TPEQIEEAVEAAINRHRPQLLVERYHFNMGLLMG-EARAVLKWADGKMIKNEVDMQVLHL 200 Query: 178 LGPKDERDLIKK---KTKNNEKKKTNSAKKSSDNSASSGPKRTMFNE--GFLGDLHKVGE 232 LGPK E DL KK E+ +AK +N ++ ++ + G HK GE Sbjct: 201 LGPKLEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGE 260 Query: 233 N---------PQAYPELMKEHLEVTGGKVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHN 283 N P L+K+HLE+TGG+VRTRFPPEPNG LHIGH+KAI NFGYAK +N Sbjct: 261 NYKTPGYVVTPHTM-NLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANN 319 Query: 284 GTCYLRFDDTNPEKEAPEYFESIKRMVSWLGFKPWKITYSSDYFDELYRLAEVLIKNGKA 343 G C+LRFDDTNPEKE ++F +I MV+WLG+ P+K+TY+SDYFD+LY A LI+ G A Sbjct: 320 GICFLRFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLA 379 Query: 344 YVCHCTAEEIKRGRGIKEDGTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRM 403 YVCH EE+K G RD+ +E++L F MR GK+ GEA LRM Sbjct: 380 YVCHQRGEELK-----------GHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRM 428 Query: 404 KQDLNSPSPQMWDLIAYRVLNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFY 463 K + D +AYRV PH RTG KW IYPTYD+THCL DS+E+ITHSLCT EF Sbjct: 429 KLVMEDGKM---DPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQ 485 Query: 464 LSRESYEWLCDQVHVFRPAQREYGRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEA 523 R SY WLC+ + V+ P Q EYGRLN+ V+SKRKI QLV VR WDDPRLFTL A Sbjct: 486 ARRSSYFWLCNALDVYCPVQWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTA 545 Query: 524 IRRRGVPPGAILSFINTLGVTTSTTNIQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDN 583 +RRRG PP AI +F +GVT + T ++ E+ VR L DT PR M VL+ + V++ N Sbjct: 546 LRRRGFPPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITN 605 Query: 584 LSDDYEELATIPYRPGTPEFGERTVPFTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIK 643 +P P G VPF +IER+DF E + F RL QPVGL Sbjct: 606 FPAAKSLDIQVPNFPADETKGFHQVPFAPIVFIERTDFKEE-PEPGFKRLAWGQPVGLRH 664 Query: 644 VSHTVSFKSLEKDEAGKIIRIHVNYDNKVEEGSKPKKPKTYIQWVPISSKYNSPLRVTET 703 + + + + K +G + + V +KPK +I WV + PL + E Sbjct: 665 TGYVIELQHVVKGPSGCVESLEVT----CRRADAGEKPKAFIHWV------SQPL-MCEV 713 Query: 704 RVYNQLFKSENPS---SHPEGFLKDINPESEVVYKESVMEHNFGDVVKNSPWVVDSVKNS 760 R+Y +LF+ +NP P GFL D+N S V ++++ + Sbjct: 714 RLYERLFQHKNPEDPTEVPGGFLSDLNLASLHVVDAALVDCSVA---------------- 757 Query: 761 EFYVEEDKDSKEVCRFQAMRVGYFTLDKESTTSKVILNRIVSLKDATSK 809 +K +FQ R+GYF++D +S K++ NR V+LK+ K Sbjct: 758 --------LAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGK 798 >5BNZ-A nrPDB Length = 564 Score = 712 bits (1837), Expect = 0.0, Method: Composition-based stats. Identities = 225/585 (38%), Positives = 319/585 (54%), Gaps = 48/585 (8%) Query: 236 AYPELMKEHLEV-----TGGKVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRF 290 A P +++ ++ K+ TRFPPEPNGYLHIGH+K+I +NFG A+ G C+LRF Sbjct: 16 AAPNFLRQIVQADLDAGKHAKIVTRFPPEPNGYLHIGHAKSICLNFGLAQEFAGDCHLRF 75 Query: 291 DDTNPEKEAPEYFESIKRMVSWLGFKP-WKITYSSDYFDELYRLAEVLIKNGKAYVCHCT 349 DDTNP KE EY ++I+ + WLGF+ ++ Y+S+YFD+L+ A LIK GKA+VC Sbjct: 76 DDTNPAKEDQEYIDAIEADIKWLGFQWSGEVCYASNYFDQLHAWAVELIKAGKAFVCDLG 135 Query: 350 AEEIKRGRGIKEDGTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNS 409 EE++ RG + PG +RD+S+E+NL F M+ G++ G LR K D+ S Sbjct: 136 PEEMREYRGTLTE--PGRN---SPYRDRSVEENLDLFARMKAGEFPDGARSLRAKIDMGS 190 Query: 410 PSPQMWDLIAYRVLNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESY 469 P+ + D I YR+ +A H +TG KW IYP+YDFTH D++E ITHS+CT EF R Y Sbjct: 191 PNMNLRDPILYRIRHAHHHQTGDKWCIYPSYDFTHGQSDAIEGITHSICTLEFEDHRPLY 250 Query: 470 EWLCDQVHVF-RPAQREYGRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRG 528 EW + V +P Q E+ RLN+ TV SKRK+ QLVDE V GWDDPR+ TL RRRG Sbjct: 251 EWFLANLPVPAQPRQYEFSRLNLNYTVTSKRKLKQLVDEGHVSGWDDPRMSTLSGYRRRG 310 Query: 529 VPPGAILSFINTLGVTTSTTNIQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDNLSDDY 588 P +I +F +GV ++ + + E ++R +L+ T PR M VL P++VV+ N + Sbjct: 311 YTPESIRNFCEMIGVNRASGVVDIGMLEFSIRDHLDATAPRAMCVLKPLKVVITNYPEGQ 370 Query: 589 EELATIPYRPGTPEFGERTVPFTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIKVSHTV 648 E +P P + G R +PF + +I+ DF E V + RL P V L + S+ + Sbjct: 371 VENLELPRHP-KEDMGVRVLPFGRELFIDAGDF-EEVPPAGYKRLIPGGEVRL-RGSYVI 427 Query: 649 SFKSLEKDEAGKIIRIHVNYDNKV-EEGSKPKKPKTYIQWVPISSKYNSPLRVTETRVYN 707 KD G I+ + +YD + + +K K I WVP E R+Y+ Sbjct: 428 RADEAIKDADGNIVELRCSYDPDTLGKNPEGRKVKGVIHWVPAEGSVE-----CEVRLYD 482 Query: 708 QLFKSENPSSHPEG--FLKDINPESEVVYKESVMEHNFGDVVKNSPWVVDSVKNSEFYVE 765 +LF+S NP EG FL +IN +S V E + G Sbjct: 483 RLFRSANPEKAEEGGSFLDNINADSLQVLAGCRAEPSLGQ-------------------- 522 Query: 766 EDKDSKEVCRFQAMRVGYFTLD-KESTTSKVILNRIVSLKDATSK 809 + RFQ R GYF D K+S K + NR V+L+D+ + Sbjct: 523 ----ANPEDRFQFEREGYFVADLKDSRPGKPVFNRTVTLRDSWGQ 563 >2RD2-A nrPDB Length = 556 Score = 694 bits (1791), Expect = 0.0, Method: Composition-based stats. Identities = 235/560 (41%), Positives = 320/560 (57%), Gaps = 44/560 (7%) Query: 252 VRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVS 311 V TRFPPEPNGYLHIGH+K+I +NFG A+ + G C LRFDDTNP KE EY ESIK V Sbjct: 28 VHTRFPPEPNGYLHIGHAKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVESIKNDVE 87 Query: 312 WLGFKP-WKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKEDGTPGGERY 370 WLGF + YSSDYFD+L+ A LI G AYV T E+I+ RG PG Sbjct: 88 WLGFHWSGNVRYSSDYFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQ--PGKN-- 143 Query: 371 ACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAYRVLNAPHPRT 430 +RD+S+E+NL F MR G ++ G+A LR K D+ SP M D + YR+ A H +T Sbjct: 144 -SPYRDRSVEENLALFEKMRAGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQT 202 Query: 431 GTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHVF-RPAQREYGRL 489 G KW IYP YDFTHC+ D++E ITHSL T EF +R Y+W+ D + + P Q E+ RL Sbjct: 203 GNKWCIYPMYDFTHCISDALEGITHSLRTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRL 262 Query: 490 NITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINTLGVTTSTTN 549 N+ TV+SKRK+ LV +K V GWDDPR+ T+ +RRRG +I F +GVT Sbjct: 263 NLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNT 322 Query: 550 IQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDNLSDDYEELATIPYRPGTPEFGERTVP 609 I++ ES +R+ L + PR M V+DPV++V++N + E + T+P P PE G R VP Sbjct: 323 IEMASLESCIREDLNENAPRAMAVIDPVKLVIENYQGEGE-MVTMPNHPNKPEMGSRQVP 381 Query: 610 FTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIKVSHTVSFKSLEKDEAGKIIRIHVNYD 669 F+ + +I+R+DF E +K++ RL + V L + ++ + + +EKD G I I YD Sbjct: 382 FSGEIWIDRADFREEA-NKQYKRLVLGKEVRL-RNAYVIKAERVEKDAEGNITTIFCTYD 439 Query: 670 NKV--EEGSKPKKPKTYIQWVPISSKYNSPLRVTETRVYNQLFKSENPSSHPEGFLKDIN 727 ++ + +K K I WV S+ + P+ E R+Y++LF NP + + FL IN Sbjct: 440 ADTLSKDPADGRKVKGVIHWV--SAAHALPV---EIRLYDRLFSVPNPGAADD-FLSVIN 493 Query: 728 PESEVVYKESVMEHNFGDVVKNSPWVVDSVKNSEFYVEEDKDSKEVCRFQAMRVGYFTLD 787 PES V+ K+ E + D V FQ R GYF LD Sbjct: 494 PESLVI-KQGFAEPSLKDAVAGKA------------------------FQFEREGYFCLD 528 Query: 788 -KESTTSKVILNRIVSLKDA 806 + ST K + NR V L+D Sbjct: 529 SRHSTAEKPVFNRTVGLRDT 548 >2HZ7-A nrPDB Length = 851 Score = 657 bits (1695), Expect = 0.0, Method: Composition-based stats. Identities = 218/608 (35%), Positives = 310/608 (50%), Gaps = 64/608 (10%) Query: 239 ELMKEHLEVTG-GKVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEK 297 E+++ LE +V TRFPP+P+GY H+GH A +++F A+ + G LR DDTNPE Sbjct: 53 EIIERDLEAGKYPRVVTRFPPDPSGYAHLGHVFASLLDFNTARQYGGQFNLRMDDTNPEL 112 Query: 298 EAPEYFESIKRMVSWLGFKPW-KITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRG 356 EY +SI + WLG Y+SDYFD Y AE LI+ G AYV + EE+ R Sbjct: 113 ARQEYVDSIADDLKWLGLDWGEHFYYASDYFDRYYAYAEQLIRQGDAYVESVSPEELSRL 172 Query: 357 RGIKEDGTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWD 416 RG +RD+S+E+NL R M+ G++ GE +LR K DL +P+ ++ D Sbjct: 173 RG-----NATTPGTPSPYRDRSVEENLDLLRRMKAGEFADGEHVLRAKIDLTAPNMKLRD 227 Query: 417 LIAYRVLNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQV 476 + YR++N PH RT +W IYP YDF H L D++E +THS+C+ EF +R Y+WL +++ Sbjct: 228 PVLYRIVNKPHFRTSDEWHIYPAYDFEHPLQDAIEGVTHSMCSLEFVDNRAIYDWLMEKL 287 Query: 477 HV-FRPAQREYGRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAIL 535 + RP Q E+GR + T+ SKRK+ +LV V GWDDPR+ TL A RR GV P A+ Sbjct: 288 NFDPRPHQYEFGRRGLEYTITSKRKLRELVQAGRVSGWDDPRMPTLRAQRRLGVTPEAVR 347 Query: 536 SFINTLGVTTSTTNIQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDNLSDDYEELATIP 595 +F +GV+ + + + +E+AVR L PR+M VLDPV+V + NL D E+ ++P Sbjct: 348 AFAAQIGVSRTNRTVDIAVYENAVRDDLNHRAPRVMAVLDPVKVTLTNL--DGEKTLSLP 405 Query: 596 YRPGT-------------------PEFGERTVPFTNKFYIERSDFSENVDDKEFFRLTPN 636 Y P PE R VP T + YIER DFS K F RLTP Sbjct: 406 YWPHDVVRDSPDGLVGMPGGGRVAPEEAVRDVPLTRELYIERDDFSP-APPKGFKRLTPG 464 Query: 637 QPVGLIKVSHTVSFKSLEKDEAGKIIRIHVNYDNKVEEGSKPKKPKTYIQWVPISSKYNS 696 V L + + + DEAG++ I + K I WV S++ Sbjct: 465 GTVRL-RGAGIIRADDFGTDEAGQVTHIRATLLG------EDAKAAGVIHWV--SAERAL 515 Query: 697 PLRVTETRVYNQLFKSENPSSHPEGFLKDINPESEVVYKESVMEHNFGDVVKNSP----- 751 P E R+Y++LF+ HPEG D+ +S + E G + +P Sbjct: 516 P---AEFRLYDRLFRVP----HPEGENADVEDDSA---GPAEHEAEPGAGQETAPVSQGF 565 Query: 752 ---WVVDSVKNSEFYVEEDKDSKE-VCRFQAMRVGYFTLDK------ESTTSKVILNRIV 801 DS++ YVE R+Q R GYF D +S ++ RI+ Sbjct: 566 MRYLTPDSLRVLRGYVEPSVAGDPADTRYQFERQGYFWRDPVELERVDSREDALVFGRII 625 Query: 802 SLKDATSK 809 +LKD K Sbjct: 626 TLKDTWGK 633 >4P2B-A nrPDB Length = 576 Score = 641 bits (1653), Expect = 0.0, Method: Composition-based stats. Identities = 222/572 (38%), Positives = 302/572 (52%), Gaps = 55/572 (9%) Query: 252 VRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVS 311 V TRFPPEPNG+LH+GH+K++ +NFG AK G C+LRFDDTNP KE Y ESI+R V Sbjct: 41 VITRFPPEPNGFLHLGHAKSVCLNFGLAKAFGGRCHLRFDDTNPMKEETRYIESIQRDVR 100 Query: 312 WLGFKPW--KITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKEDGTPGGER 369 WLG W + Y+SDYF +LY AE+LIK G A+V + EEI+R RG PG Sbjct: 101 WLG-GDWGNHLYYASDYFQQLYDWAELLIKKGLAFVDDDSLEEIRRKRG--SISQPGEN- 156 Query: 370 YACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAYRVLNAPHPR 429 R++SIE+NL FR MR G+++ G +LR K D+ + M D + YR+L HPR Sbjct: 157 --SPFRERSIEENLDLFRRMRAGEFEEGSRVLRAKIDMTHSNMNMRDPVLYRILKKEHPR 214 Query: 430 TGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHVFRPAQREYGRL 489 TG +W IYP YD+ H DS+ENITHS+CT EF L R Y+W +++ + R Q E+ RL Sbjct: 215 TGNQWVIYPMYDYAHGQSDSIENITHSICTLEFDLHRILYDWFQEKLEITRTRQIEFARL 274 Query: 490 NITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINTLGVTTSTTN 549 N+T TV+SKRK+ LV EK+V GWDDPRL TL +RRRGVPP A+ F + +GV + Sbjct: 275 NVTYTVMSKRKLLALVTEKWVDGWDDPRLPTLSGLRRRGVPPSALRDFCDKVGVARREST 334 Query: 550 IQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDNLSDDYEELATIPYRPGTPEFGERTVP 609 I+V E +R L R + DP+ V + N D E T P FG R + Sbjct: 335 IKVEVLEKCIRDALHVVAHRRFAIQDPIAVTITNY-GDKVETITAANHPEDESFGTRELH 393 Query: 610 FTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIKVSHTVSFKSLEKDEAGKIIRIHVNYD 669 F+ K YI+R DF EN + RL P V L K ++ + + KD +G + + YD Sbjct: 394 FSKKLYIDRDDFMEN-PPAGYRRLAPGAEVRL-KHAYWIKCVDVVKDASGLVTELLCTYD 451 Query: 670 NKVEEG---SKPKKPKTYIQWVPISSKYNSPLRVTETRVYNQLFKSENPSSHPE-----G 721 + + +K K I W +S K P E R++ +LF NP E Sbjct: 452 PQTKNCSVAPDGRKVKGAIHW--LSEKDAVP---AEIRIFGRLFTKPNPEEEDESNPNAS 506 Query: 722 FLKDINPESEVVYKESVMEHNFGDVVKNSPWVVDSVKNSEFYVEEDKDSKEVCRFQAMRV 781 + ++IN ES VYK +E + D P Q R+ Sbjct: 507 WRENINKESLKVYK-GFVERSAADSAAFPPQSS---------------------LQFERL 544 Query: 782 GYFTLDKESTTSK---------VILNRIVSLK 804 G+FT D + + + N V+L+ Sbjct: 545 GFFTPDGSTLPEEADNTKTRTLPVFNLTVALQ 576 >5ZDO-A nrPDB Length = 548 Score = 627 bits (1617), Expect = e-180, Method: Composition-based stats. Identities = 224/570 (39%), Positives = 330/570 (57%), Gaps = 58/570 (10%) Query: 250 GKVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRM 309 K+ TRFPPEPNGYLHIGH+++I++NFG A+ + G C LRFDDTNPE E EY +I+ Sbjct: 23 AKLVTRFPPEPNGYLHIGHARSIVLNFGLAQDYGGECNLRFDDTNPETEKEEYARAIEED 82 Query: 310 VSWLGFKPWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKEDGTPGGER 369 V WLGF+P ++ Y+SDYF+ +Y+ A VLI+ GKAYV EE+ R G P Sbjct: 83 VRWLGFRPTRVLYASDYFETMYQCALVLIQEGKAYVDDLPEEEMSELRA---QGKP---- 135 Query: 370 YACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAYRVLNAPHPR 429 +R++S+E+NL+ F MR G++ G +LR K D P+ ++ D + YR+++APH Sbjct: 136 --SPYRERSVEENLELFERMRRGEFPTGSRVLRAKIDPAHPNFKLRDPVLYRIVHAPHYH 193 Query: 430 TGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQV-------HVFRPA 482 G +W IYP YDF H L D +E +THSLCT EF +R Y+W+ + + RP Sbjct: 194 VGDRWVIYPMYDFAHPLEDFIEGVTHSLCTLEFENNRTVYDWVIENLKGKCGLPTSPRPH 253 Query: 483 QREYGRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINTLG 542 Q E+ RL+++ TVLSKRK+ +LV+ +V GWDDPRL TL +RRRGV P AI+ F+ G Sbjct: 254 QYEFARLDLSHTVLSKRKLIKLVEGGYVSGWDDPRLPTLRGLRRRGVRPEAIVEFVRKTG 313 Query: 543 VTTSTTNIQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDNLSDDYEELATIPYRP-GTP 601 ++ + I++ FE VR L PR++ V+DP++VV+ N EE PY P P Sbjct: 314 ISRNEAQIEMDLFEEVVRDDLNPIAPRVLGVVDPLKVVLTNYEG--EEWIEAPYWPRDIP 371 Query: 602 EFGERTVPFTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIKVSHTVSFKSLEKDEAGKI 661 + G R +PF+ + YIER+DFS N K + RL P Q V L + ++ + + + E G Sbjct: 372 KEGTRPLPFSPELYIERTDFSLN-PPKGWKRLAPGQRVRL-RHAYVIELEDVV--EEGGE 427 Query: 662 IRIHVNYDNKVEEGSKPK---KPKTYIQWVPISSKYNSPLRVTETRVYNQLFKSENPSSH 718 +R+ G+ P+ +PK I WV S+++ P+ E R+Y +LF++++P Sbjct: 428 VRLLKARIVPGTLGANPEDGVRPKGVIHWV--SARHALPV---EFRLYGRLFRTKDPEEG 482 Query: 719 PEGFLKDINPESEVVYKESVMEHNFGDVVKNSPWVVDSVKNSEFYVEEDKDSKEVCRFQA 778 + FL+++NPE+ VV K +E + V P E R+Q Sbjct: 483 GD-FLQNLNPEALVV-KRGFIEPS----VAQDP--------------------EDTRYQL 516 Query: 779 MRVGYFTLDK-ESTTSKVILNRIVSLKDAT 807 R+GYF D +S +++NRIV LK+ Sbjct: 517 ERLGYFWRDPVDSRPEALVMNRIVPLKEGY 546 >3AII-A nrPDB Length = 553 Score = 458 bits (1178), Expect = e-129, Method: Composition-based stats. Identities = 144/475 (30%), Positives = 221/475 (46%), Gaps = 40/475 (8%) Query: 228 HKVGENPQAYPELMKEHLEVTGGKVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCY 287 ++ E Q + ++E L G+V RF P P+G LHIGH++A ++N YA+ ++G Sbjct: 74 LEITERKQKKRKGLRE-LAGVKGEVVLRFAPNPSGPLHIGHARAAILNHEYARKYDGRLI 132 Query: 288 LRFDDTNPEKEAPEYFESIKRMVSWLGFKPWKITYSSDYFDELYRLAEVLIKNGKAYVCH 347 LR +DT+P + PE ++ I + WLG + + SD + Y E LI+ G AYVC Sbjct: 133 LRIEDTDPRRVDPEAYDMIPADLEWLGVEWDETVIQSDRMETYYEYTEKLIERGGAYVCT 192 Query: 348 CTAEEIKRGRGIKEDGTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDL 407 C EE R +K G C R +NLQ +R+M + K G A++R+K DL Sbjct: 193 CRPEEF---RELKNRGEA------CHCRSLGFRENLQRWREMF--EMKEGSAVVRVKTDL 241 Query: 408 NSPSPQMWDLIAYRVLNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRE 467 N P+P + D ++ R++ A HPRTGT++R+YP +F+ + D + +TH L + +RE Sbjct: 242 NHPNPAIRDWVSMRIVEAEHPRTGTRYRVYPMMNFSVAVDDHLLGVTHVLRGKDHLANRE 301 Query: 468 SYEWLCDQVHVFRPAQREYGRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRR 527 E+L + P YGRL + LS + + GWDDPRL TL AI RR Sbjct: 302 KQEYLYRHLGWEPPEFIHYGRLKMDDVALSTSGAREGILRGEYSGWDDPRLGTLRAIARR 361 Query: 528 GVPPGAILSFINTLGVTTSTTNIQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDNLSDD 587 G+ P AI + +GV + + + + R LE+ R F DPV++ V L Sbjct: 362 GIRPEAIRKLMVEIGVKIADSTMSWKKIYGLNRSILEEEARRYFFAADPVKLEVVGLPGP 421 Query: 588 YEELATIPYRPGTPEFGERTVPFTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIKVSHT 647 P P PE G R + + Y+ D E P+ LI + Sbjct: 422 VR--VERPLHPDHPEIGNRVLELRGEVYLPGDDLGE-------------GPLRLIDAVNV 466 Query: 648 VSFKSLEKDEAGKIIRIHVNYDNKVEEGSKPKKPKTYIQWVPISSKYNSPLRVTE 702 + +G +R H + E + I WVP S + + + + Sbjct: 467 IY--------SGGELRYHSEGIEEARELG-----ASMIHWVPAESALEAEVIMPD 508 >6BRL-A nrPDB Length = 511 Score = 332 bits (850), Expect = 5e-91, Method: Composition-based stats. Identities = 74/332 (22%), Positives = 138/332 (41%), Gaps = 28/332 (8%) Query: 251 KVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMV 310 KVR RF P P G LH+G + + ++ +AK++ G LR +DT+ ++ P E I + Sbjct: 11 KVRVRFAPSPTGPLHLGGVRTALYDYLFAKHNGGDFILRIEDTDTQRYVPGSEEYIMEAL 70 Query: 311 SWLGF---------KPWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKE 361 W+G P+ S+ D R E ++K AY+ T EE+ + R Sbjct: 71 EWIGMVPDESPKHGGPYAPYRQSERRDIYDRYTEQILKTDYAYLAFDTPEELDQIRA--- 127 Query: 362 DGTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEA--ILRMKQDLNSPSPQMWDLIA 419 + G+ +A + ++ +N + K + ++R K L+ + D+I Sbjct: 128 EFEARGDVFAYNYETRNRLRNSISLPEEEVKKLLEEKTPYVIRFKMPLDR-IINLNDIIR 186 Query: 420 YRV---LNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQV 476 + N + K PTY F + + D ITH + E+ S + L + + Sbjct: 187 GKFSVNTNTLDDKVLVKNDGMPTYHFANIIDDHEMKITHVIRGEEWLPSMALHVLLYEAM 246 Query: 477 HVFRPAQREYGRLNITGTVLSKRKIAQLVDEKF------VRGWDDPRLFTLEAIRRRGVP 530 P E+ L++ K K+++ +KF + D T R G Sbjct: 247 GWDAP---EFAHLSLILKPEGKGKLSKRDGDKFGFPVFPLNFTDSATGNTSAGYREEGYL 303 Query: 531 PGAILSFINTLGVTTSTTNIQVVRFESAVRKY 562 P A ++ + LG + + N ++V + ++++ Sbjct: 304 PEAFINMVAMLGWSPAD-NKEIVSMDEMIKEF 334 >3AL0-C nrPDB Length = 592 Score = 316 bits (809), Expect = 2e-86, Method: Composition-based stats. Identities = 105/528 (19%), Positives = 183/528 (34%), Gaps = 96/528 (18%) Query: 115 IEITEDQVRNYVMQYIQENKERILTERYKLVPGI---FADVKNLKELKWADPRSFKPIID 171 +E++EDQ R +M+ QE + + V G+ + V++ +L+ DPR F Sbjct: 19 LELSEDQ-RESLMKDFQEILDYVELLNEVDVEGVEPMYTPVEDSAKLRKGDPRFF----- 72 Query: 172 QEVLKLLGPKDERDLIKKKTKNNEKKKTNSAKKSSDNSASSGPKRTMFNEGFLGDLHKVG 231 + RDLIKK N ++K K + S +MF G D+ +VG Sbjct: 73 ----------EMRDLIKK---NFPEEKDGHIKVPGIHRGSGSGSGSMFITGAFFDILEVG 119 Query: 232 ENPQAYPELMKEHLEVTGGKVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFD 291 P+ ++ E+ VR RF P P G+LH+G ++ + N+ +A+ G LR + Sbjct: 120 ------PKKIRRCFEL----VRVRFAPSPTGHLHVGGARTALFNWMFARKEGGKFILRIE 169 Query: 292 DTNPEKEAPEYFESIKRMVSWLGFKPWK---------ITYSSDYFDELYRLAEVLIKNGK 342 DT+ E+ + EY + I + W G + S+ + AE L+++ + Sbjct: 170 DTDTERSSREYEQQILESLRWCGLDWDEGPDIGGDFGPYRQSERLEIYREYAEKLVEDKR 229 Query: 343 AYVCHCTAEEIKRGRGIKEDGTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILR 402 AY E+ Y H + + K PG+ Sbjct: 230 AYYVVYDKED---------PSKELFTTYEYPHEYKE-----KGHPVTIKFKVLPGKTSFE 275 Query: 403 --MKQDLNSPSPQMWDLIAYRVLNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTT 460 +K + + + D I K +PTY+F + D + I+H Sbjct: 276 DLLKGYMEFDNSTLEDFIIM------------KSNGFPTYNFAVVVDDHLMRISHVFRGE 323 Query: 461 EFYLSRESYEWLCDQVHVFRPAQREYGR-LNITGTVLSKRKIAQLVDEKFVRGWDDPRLF 519 + + + + P L T LSKR A V+ Sbjct: 324 DHLSNTPKQLMIYEAFGWEAPVFMHIPLILGSDRTPLSKRHGATSVEH------------ 371 Query: 520 TLEAIRRRGVPPGAILSFINTLGVTTSTTNIQVVRFESAVRKYLEDTTPRLMFVLDPVEV 579 RR G+ A+++++ LG ++ E ++ + + D ++ Sbjct: 372 ----FRREGILSRALMNYLALLGWRVEGD--EIFTIEEKLQSFDPKDISNKGVIFDYQKL 425 Query: 580 VVDN--------LSDDYEELATIPYRPGTPEFGERTVPFTNKFYIERS 619 N L D E G F+ I R Sbjct: 426 EWVNGKHMRRIDLEDLKREFIEWAKYAGKEIPSVDERYFSETLRICRE 473 >5TGT-A nrPDB Length = 502 Score = 300 bits (767), Expect = 2e-81, Method: Composition-based stats. Identities = 73/323 (22%), Positives = 117/323 (36%), Gaps = 48/323 (14%) Query: 252 VRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVS 311 VRTR P P G H+G + + N +A+ H G LR +DT+ + E + I + Sbjct: 12 VRTRIAPSPTGDPHVGTAYIALFNLCFARQHGGQFILRIEDTDQLRSTRESEQQIYDALR 71 Query: 312 WLGF---------KPWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRG--IK 360 WLG P S+ + ++ L++ G A+ C CT E + R + Sbjct: 72 WLGIEWDEGPDVGGPHGPYRQSERGHIYKKYSDELVEKGHAFTCFCTPERLDAVRAEQMA 131 Query: 361 EDGTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAY 420 TP + + +++ L P E + + L WD + Sbjct: 132 RKETPRYDGHCMHLPKDEVQRRLAAGESHVTRMKVPTEGVCVVPDMLRGDVEIPWDRMDM 191 Query: 421 RVLNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSR-------ESYEWLC 473 +VL K PTY + + D + ITH L E+ S E + W Sbjct: 192 QVL--------MKADGLPTYFLANVVDDHLMGITHVLRGEEWLPSAPKLIKLYEYFGWEQ 243 Query: 474 DQVHVFRPAQREYGRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGA 533 Q+ + P R N + LSKRK +P T R G P A Sbjct: 244 PQL-CYMPLLR-----NPDKSKLSKRK--------------NPTSITF--YERMGYLPQA 281 Query: 534 ILSFINTLGVTTSTTNIQVVRFE 556 +L+++ +G + + E Sbjct: 282 LLNYLGRMGWSMPDEREKFTLAE 304 >3TL4-X nrPDB Length = 187 Score = 299 bits (764), Expect = 5e-81, Method: Composition-based stats. Identities = 187/187 (100%), Positives = 187/187 (100%) Query: 1 MSSVEELTQLFSQVGFEDKKVKEIVKNKKVSDSLYKLIKETPSDYQWNKSTRALVHNLAS 60 MSSVEELTQLFSQVGFEDKKVKEIVKNKKVSDSLYKLIKETPSDYQWNKSTRALVHNLAS Sbjct: 1 MSSVEELTQLFSQVGFEDKKVKEIVKNKKVSDSLYKLIKETPSDYQWNKSTRALVHNLAS 60 Query: 61 FVKGTDLPKSELIVNGIINGDLKTSLQVDAAFKYVKANGEASTKMGMNENSGVGIEITED 120 FVKGTDLPKSELIVNGIINGDLKTSLQVDAAFKYVKANGEASTKMGMNENSGVGIEITED Sbjct: 61 FVKGTDLPKSELIVNGIINGDLKTSLQVDAAFKYVKANGEASTKMGMNENSGVGIEITED 120 Query: 121 QVRNYVMQYIQENKERILTERYKLVPGIFADVKNLKELKWADPRSFKPIIDQEVLKLLGP 180 QVRNYVMQYIQENKERILTERYKLVPGIFADVKNLKELKWADPRSFKPIIDQEVLKLLGP Sbjct: 121 QVRNYVMQYIQENKERILTERYKLVPGIFADVKNLKELKWADPRSFKPIIDQEVLKLLGP 180 Query: 181 KDERDLI 187 KDERDLI Sbjct: 181 KDERDLI 187 >4GRI-A nrPDB Length = 512 Score = 271 bits (693), Expect = 7e-73, Method: Composition-based stats. Identities = 74/309 (23%), Positives = 119/309 (38%), Gaps = 45/309 (14%) Query: 253 RTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVSW 312 R R+ P P G HIG + + N+ +AK G LR +DT+ + +PE + + W Sbjct: 26 RVRYAPSPTGLQHIGGIRTALFNYFFAKSCGGKFLLRIEDTDQSRYSPEAENDLYSSLKW 85 Query: 313 LGF---------KPWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKEDG 363 LG + S + A+ LI++G AY C+C+ E ++R + I+ Sbjct: 86 LGISFDEGPVVGGDYAPYVQSQRSAIYKQYAKYLIESGHAYYCYCSPERLERIKKIQNIN 145 Query: 364 T--PGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAYR 421 PG +R+ ++ +E L K KP ++R K L + D++ R Sbjct: 146 KMPPGYDRHCRNLSNEEVENALI-------KKIKP---VVRFKIPLEGDT-SFDDILLGR 194 Query: 422 VLNA-----PHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQV 476 + A P P K PTY + + D + ITH L E+ S + L Sbjct: 195 ITWANKDISPDPVI-LKSDGLPTYHLANVVDDYLMKITHVLRAQEWVSSGPLHVLLYKAF 253 Query: 477 HVFRPAQREYGR-LNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAIL 535 P + G LSKR + L G P AI+ Sbjct: 254 KWKPPIYCHLPMVMGNDGQKLSKRHGST----------------ALRQFIEDGYLPEAII 297 Query: 536 SFINTLGVT 544 +++ LG + Sbjct: 298 NYVTLLGWS 306 >2CFO-A nrPDB Length = 492 Score = 248 bits (633), Expect = 7e-66, Method: Composition-based stats. Identities = 70/334 (20%), Positives = 127/334 (38%), Gaps = 34/334 (10%) Query: 252 VRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVS 311 VR R P P G LHIG ++ + N+ YA++ G LR +DT+ E+ PEY E+I + Sbjct: 2 VRVRLAPSPTGNLHIGTARTAVFNWLYARHRGGKFILRIEDTDRERSRPEYTENILEGLQ 61 Query: 312 WLGFKPWKITY-SSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKEDGTPGGERY 370 WLG + Y SD D + + L+ G AY C+CT EE++ R ++ RY Sbjct: 62 WLGLTWDEGPYFQSDRLDLYRQAIQTLLDKGLAYYCYCTPEELEALRA-EQKAKGQAPRY 120 Query: 371 ACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAYRVLNAPHPRT 430 +HR + E+ R ++R K + + + DL+ RV Sbjct: 121 DNRHRHLTPEEQAAFEAAGRT-------PVIRFKIE-DDRQIEWQDLVRGRVSWQGADLG 172 Query: 431 GTK---------WRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHVFRP 481 G YP Y+ + D IT + + + L + + P Sbjct: 173 GDMVIARAAPRGEIGYPLYNLVVVVDDIAMGITDVIRGEDHIGNTPKQILLYEALGATPP 232 Query: 482 AQREYGRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINTL 541 + + + K+++ + ++ R G A+ +++ L Sbjct: 233 ---NFAHTPLILNSTGQ-KLSKRDG-----------VTSISDFRAMGYLAPALANYMTLL 277 Query: 542 GVTTSTTNIQVVRFESAVRKYLEDTTPRLMFVLD 575 G + ++ + A + + + + D Sbjct: 278 GWSPPEGVGELFTLDLAAKHFSFERINKAGARFD 311 >2CV2-A nrPDB Length = 468 Score = 247 bits (631), Expect = 1e-65, Method: Composition-based stats. Identities = 74/372 (19%), Positives = 130/372 (34%), Gaps = 46/372 (12%) Query: 252 VRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVS 311 V TR P P G H+G + + N+ +A+ + G +R +DT+ + P E I + Sbjct: 2 VVTRIAPSPTGDPHVGTAYIALFNYAWARRNGGRFIVRIEDTDRARYVPGAEERILAALK 61 Query: 312 WLGF---------KPWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKED 362 WLG P S+ + AE L+K G AY T EE+++ R Sbjct: 62 WLGLSYDEGPDVGGPHGPYRQSERLPLYQKYAEELLKRGWAYRAFETPEELEQIR----K 117 Query: 363 GTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAYRV 422 G + A + E+ + P +K +L ++ Y Sbjct: 118 EKGGYDGRARNIPPEEAEERARRGEPHVIRLKVPRPGTTEVKDELRG-------VVVYDN 170 Query: 423 LNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHVFRPA 482 P K YPTY + + D + +T + E+ +S + L P Sbjct: 171 QEIPD-VVLLKSDGYPTYHLANVVDDHLMGVTDVIRAEEWLVSTPIHVLLYRAFGWEAPR 229 Query: 483 QREYGRL-NITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINTL 541 L N T +SKRK +L+ + G P A+ +++ + Sbjct: 230 FYHMPLLRNPDKTKISKRKSHT----------------SLDWYKAEGFLPEALRNYLCLM 273 Query: 542 GVTTSTTNIQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDNLSDDYEELATIPYRPGTP 601 G + ++ E ++ + + V D ++ N E+ ++ Sbjct: 274 GFSMPDG-REIFTLEEFIQAFTWERVSLGGPVFDLEKLRWMN-GKYIREVLSL------E 325 Query: 602 EFGERTVPFTNK 613 E ER PF + Sbjct: 326 EVAERVKPFLRE 337 >6B1P-A nrPDB Length = 471 Score = 236 bits (601), Expect = 4e-62, Method: Composition-based stats. Identities = 69/314 (21%), Positives = 121/314 (38%), Gaps = 39/314 (12%) Query: 252 VRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVS 311 + TRF P P GYLHIG + + N+ +A+ + G +LR +DT+ + + E +I Sbjct: 12 IVTRFAPSPTGYLHIGGLRTAIFNYLFARANQGKFFLRIEDTDLSRNSIEAANAIIEAFK 71 Query: 312 WLGFK-PWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKEDGTPGGERY 370 W+G + +I Y S F+ + L+ KAY C+ + +E+ R ++ RY Sbjct: 72 WVGLEYDGEILYQSKRFEIYKEYIQKLLDEDKAYYCYMSKDELDALRE-EQKARKETPRY 130 Query: 371 ACKHRDQSIEQNLQEFRDMRDGKYKPG-EAILRMKQDLNSPSPQMWDLIAYRV---LNAP 426 ++RD G G E ++R+K N D + V N Sbjct: 131 DNRYRD-------------FKGTPPKGIEPVVRIKVPQN-EVIGFNDGVKGEVKVNTNEL 176 Query: 427 HPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHVFRPAQREY 486 + PTY+F + D++ IT + + + L ++ P Sbjct: 177 DDFIIARSDGTPTYNFVVIVDDALMGITDVIRGDDHLSNTPKQIVLYKALNFKIPNFFHV 236 Query: 487 GR-LNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINTLGVTT 545 LN G LSKR A V + + G A+++F+ LG + Sbjct: 237 PMILNEEGQKLSKRHGATNVMD----------------YQEMGYLKEALVNFLVRLGWSY 280 Query: 546 STTNIQVVRFESAV 559 ++ + + Sbjct: 281 QD--KEIFSMQELL 292 >5H4V-A nrPDB Length = 488 Score = 235 bits (598), Expect = 7e-62, Method: Composition-based stats. Identities = 70/331 (21%), Positives = 117/331 (35%), Gaps = 49/331 (14%) Query: 253 RTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVSW 312 RTRF P P GYLHIG ++ + + A+ G LR +DT+ ++ ++I + W Sbjct: 25 RTRFAPSPTGYLHIGGARTALYCWLEARRRGGQFVLRIEDTDRQRSTQAAIDAILEAMQW 84 Query: 313 LGFKPWKIT-YSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGR--GIKEDGTPGGER 369 LG + Y + +AE L+ GKAY + T EE+ R + + P + Sbjct: 85 LGLGYDEGPIYQTQRVARYQEVAEQLLAQGKAYYAYETREELDAMREAAMAKQEKPRYDG 144 Query: 370 YAC----KHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAYRVLNA 425 A +RD ++R K + + DLI R+ A Sbjct: 145 AAREQNLPYRDDP-------------------NRVIRFKNPI-GGTVVFDDLIKGRIEIA 184 Query: 426 ---PHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHVFRPA 482 + PTY+F + D IT + + + + + P Sbjct: 185 NSELDDMVIFRPDGLPTYNFAVVVDDWDMGITEVIRGDDHINNTPRQINIYAALGAPVPK 244 Query: 483 QREYGR-LNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINTL 541 L+ GT LSKR A V + + G P A+++++ L Sbjct: 245 FAHMPMILDEQGTKLSKRTGAADVMQ----------------YKDAGYLPHALINYLARL 288 Query: 542 GVTTSTTNI--QVVRFESAVRKYLEDTTPRL 570 G + + + K + RL Sbjct: 289 GWSHGDQELFTPQELLDLFDVKDVNSKAARL 319 >3AKZ-B nrPDB Length = 487 Score = 233 bits (595), Expect = 2e-61, Method: Composition-based stats. Identities = 79/422 (18%), Positives = 139/422 (32%), Gaps = 74/422 (17%) Query: 218 MFNEGFLGDLHKVGENPQAYPELMKEHLEVTGGKVRTRFPPEPNGYLHIGHSKAIMVNFG 277 MF G D+ +VG P+ ++ E+ VR RF P P G+LH+G ++ + N+ Sbjct: 1 MFITGAFFDILEVG------PKKIRRCFEL----VRVRFAPSPTGHLHVGGARTALFNWM 50 Query: 278 YAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVSWLGFKPWK---------ITYSSDYFD 328 +A+ G LR +DT+ E+ + EY + I + W G + S+ + Sbjct: 51 FARKEGGKFILRIEDTDTERSSREYEQQILESLRWCGLDWDEGPDIGGDFGPYRQSERLE 110 Query: 329 ELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKEDGTPGGERYACKHRDQSIEQNLQEFRD 388 AE L+++ +AY E+ Y H + + Sbjct: 111 IYREYAEKLVEDKRAYYVVYDKED---------PSKELFTTYEYPHEYKE-----KGHPV 156 Query: 389 MRDGKYKPGEAILR--MKQDLNSPSPQMWDLIAYRVLNAPHPRTGTKWRIYPTYDFTHCL 446 K PG+ +K + + + D I K +PTY+F + Sbjct: 157 TIKFKVLPGKTSFEDLLKGYMEFDNSTLEDFIIM------------KSNGFPTYNFAVVV 204 Query: 447 VDSMENITHSLCTTEFYLSRESYEWLCDQVHVFRPAQREYGR-LNITGTVLSKRKIAQLV 505 D + I+H + + + + P L T LSKR A V Sbjct: 205 DDHLMRISHVFRGEDHLSNTPKQLMIYEAFGWEAPVFMHIPLILGSDRTPLSKRHGATSV 264 Query: 506 DEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINTLGVTTSTTNIQVVRFESAVRKYLED 565 + RR G+ A+++++ LG ++ E ++ + Sbjct: 265 EH----------------FRREGILSRALMNYLALLGWRVEGD--EIFTIEEKLQSFDPK 306 Query: 566 TTPRLMFVLDPVEVVVDN--------LSDDYEELATIPYRPGTPEFGERTVPFTNKFYIE 617 + D ++ N L D E G F+ I Sbjct: 307 DISNKGVIFDYQKLEWVNGKHMRRIDLEDLKREFIEWAKYAGKEIPSVDERYFSETLRIC 366 Query: 618 RS 619 R Sbjct: 367 RE 368 >2O5R-A nrPDB Length = 481 Score = 233 bits (594), Expect = 2e-61, Method: Composition-based stats. Identities = 83/400 (20%), Positives = 144/400 (36%), Gaps = 52/400 (13%) Query: 252 VRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVS 311 VR RF P P G+LH+G ++ + NF +A+ G LR +DT+ E+ EY E + + Sbjct: 14 VRVRFAPSPTGFLHVGGARTALFNFLFARKEKGKFILRIEDTDLERSEREYEEKLMESLR 73 Query: 312 WLGF---------KPWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGR-GIKE 361 WLG S+ + AE L+K GKAY + EEI+ R + Sbjct: 74 WLGLLWDEGPDVGGDHGPYRQSERVEIYREHAERLVKEGKAYYVYAYPEEIEEMREKLLS 133 Query: 362 DGTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAYR 421 +G H Q + + R+ + K + K + D++ Sbjct: 134 EGKA-------PHYSQEMFEKFDTPERRREYEEKGLRPAVFFKMP--RKDYVLNDVVKGE 184 Query: 422 VLN---APHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHV 478 V+ A + PTY+F + D + ITH + + + L + Sbjct: 185 VVFKTGAIGDFVIMRSNGLPTYNFACVVDDMLMEITHVIRGDDHLSNTLRQLALYEAFEK 244 Query: 479 FRPAQREYGR-LNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSF 537 P L G LSKR A V+ A R G P A++++ Sbjct: 245 APPVFAHVSTILGPDGKKLSKRHGATSVE----------------AFRDMGYLPEALVNY 288 Query: 538 INTLGVTTSTTNIQVVRFESAVRKYLEDTTPRLMFVLDPVEVV------VDNLSDDYEEL 591 + LG + +++ E + + D + DP ++ + N+ + Sbjct: 289 LALLGWSHPEG-KELLTLEELISSFSLDRLSPNPAIFDPQKLKWMNGYYLRNMPIEKLAE 347 Query: 592 ATIPYRPG------TPEFGERTVPFTNKFYIERSDFSENV 625 P+ E+ ++ + T + S+F E Sbjct: 348 LAKPFFEKAGIKIIDEEYFKKVLEITKERVEVLSEFPEES 387 >4G6Z-A nrPDB Length = 490 Score = 227 bits (578), Expect = 2e-59, Method: Composition-based stats. Identities = 65/304 (21%), Positives = 113/304 (37%), Gaps = 31/304 (10%) Query: 252 VRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVS 311 VRTRF P P G++H+G+ ++ + + +A+ GT LR +DT+ E+ + E ++I ++ Sbjct: 26 VRTRFAPSPTGFIHLGNIRSALYPWAFARKMKGTFVLRIEDTDVERSSQEAVDAILEGMA 85 Query: 312 WLGFKPWK-ITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKEDGTPGGERY 370 WLG + Y D + + + G Y C+ + EE+ R ++ RY Sbjct: 86 WLGLDYDEGPYYQMQRMDRYREVLAQMQEKGLVYPCYMSTEELDALRE-RQRAAGEKPRY 144 Query: 371 ACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAYRVL---NAPH 427 R + + + G +LR + L + D + RV Sbjct: 145 DGTWRPEPGK----VLPEPPAGVAP----VLRFRNPLTG-TVAWDDAVKGRVEISNEELD 195 Query: 428 PRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHVFRPAQREYG 487 + P Y+F + D ITH + + + + + P Sbjct: 196 DLVVARPDGTPMYNFCVVVDDLDMGITHVIRGDDHVNNTPRQINILRALGGEVPVYAHLP 255 Query: 488 R-LNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFINTLGVTTS 546 LN G +SKR A V R G P A+L+++ LG + Sbjct: 256 TVLNEQGEKMSKRHGAMSVM----------------GYRDAGYLPEAVLNYLARLGWSHG 299 Query: 547 TTNI 550 I Sbjct: 300 DAEI 303 >2JA2-A nrPDB Length = 498 Score = 210 bits (535), Expect = 2e-54, Method: Composition-based stats. Identities = 71/354 (20%), Positives = 124/354 (35%), Gaps = 51/354 (14%) Query: 252 VRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVS 311 VR RF P P G H+G + + N+ YA++ GT R +DT+ ++++ E + ++ + Sbjct: 7 VRVRFCPSPTGTPHVGLVRTALFNWAYARHTGGTFVFRIEDTDAQRDSEESYLALLDALR 66 Query: 312 WLGF---------KPWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKED 362 WLG P+ S + + L+ G+AY T EE++ Sbjct: 67 WLGLDWDEGPEVGGPYGPYRQSQRAEIYRDVLARLLAAGEAYHAFSTPEEVEARHVAAGR 126 Query: 363 G-TPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAYR 421 G + + D L E R LRM D + + + + + Sbjct: 127 NPKLGYDNFDRHLTDAQRAAYLAEGRQPVVR--------LRMPDDDLAWNDLVRGPVTFA 178 Query: 422 VLNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQV--HVF 479 + P T+ P Y + D++ ITH L + S L + Sbjct: 179 AGSVPDF-ALTRASGDPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQLALHQALIRIGV 237 Query: 480 RPAQREYGRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGAILSFIN 539 ++ L T +K+++ DP+ L A R RG P +L+++ Sbjct: 238 AERIPKFAHL-PTVLGEGTKKLSKR----------DPQSN-LFAHRDRGFIPEGLLNYLA 285 Query: 540 TLGVTTSTT------------------NIQVVRFESAVRKYLEDTTPRLMFVLD 575 LG + + N RF+ L R++ V D Sbjct: 286 LLGWSIADDHDLFGLDEMVAAFDVADVNSSPARFDQKKADALNAEHIRMLDVGD 339 >4A91-A nrPDB Length = 298 Score = 174 bits (441), Expect = 1e-43, Method: Composition-based stats. Identities = 58/293 (19%), Positives = 96/293 (32%), Gaps = 39/293 (13%) Query: 247 VTGGKVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESI 306 +T + RF P P+G LH G A + ++ A+ G +R +D +P +E P E+I Sbjct: 1 MTDTQYIGRFAPSPSGELHFGSLIAALGSYLQARARQGRWLVRIEDIDPPREVPGAAETI 60 Query: 307 KRMVSWLGFKPW-KITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKEDGTP 365 R + G + + S D L + G +Y C CT I+ GI Sbjct: 61 LRQLEHYGLHWDGDVLWQSQRHDAYREALAWLHEQGLSYYCTCTRARIQSIGGI------ 114 Query: 366 GGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRMKQDLNSPSPQMWDLIAYRV--- 422 + + P A +R++Q P Q D + + Sbjct: 115 -YDGHCRVLHH------------------GPDNAAVRIRQ--QHPVTQFTDQLRGIIHAD 153 Query: 423 -LNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFYLSRESYEWLCDQVHVFRP 481 A + Y+ + D + +T + + L P Sbjct: 154 EKLAREDFIIHRRDGLFAYNLAVVVDDHFQGVTEIVRGADLIEPTVRQISLYQLFGWKVP 213 Query: 482 AQREYG-RLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEAIRRRGVPPGA 533 LN G LSK+ A + + DPR + A++ G A Sbjct: 214 DYIHLPLALNPQGAKLSKQNHAPALPKG------DPRPVLIAALQFLGQQAEA 260 >2G36-A nrPDB Length = 340 Score = 37.5 bits (85), Expect = 0.022, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 22/65 (33%), Gaps = 7/65 (10%) Query: 260 PNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDD-------TNPEKEAPEYFESIKRMVSW 312 P G LHIGH + N+ + C+ D + + EY + R Sbjct: 21 PTGKLHIGHLVGALENWVKLQEEGNECFYFVADWHALTTHYDDVSKLKEYTRDLVRGFLA 80 Query: 313 LGFKP 317 G P Sbjct: 81 CGIDP 85 >3FNR-A nrPDB Length = 464 Score = 36.7 bits (83), Expect = 0.045, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 27/93 (29%), Gaps = 22/93 (23%) Query: 259 EPNGYLHIGHSKAIMVN---FGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVSWLGF 315 P G LHIGH++ + A++ N E + I LG Sbjct: 40 NPTGPLHIGHARGAVFGDTLTRLARHLGYKF-------NTEYYVNDAGNQIY----LLGL 88 Query: 316 KPWKITYSS------DYFDELY--RLAEVLIKN 340 S +Y ++ Y L K Sbjct: 89 SILLSVKESILHENVEYPEQYYKGEYIVDLAKE 121 >1IQ0-A nrPDB Length = 592 Score = 36.3 bits (82), Expect = 0.057, Method: Composition-based stats. Identities = 25/109 (22%), Positives = 39/109 (35%), Gaps = 24/109 (22%) Query: 259 EPNGYLHIGHSKAIMVNFGYAK--YHNGTCYL---RFDDTNPEKEAPEYFESIKRMVSWL 313 PN LH+GH + I + A+ + G L DDT + E++ + Sbjct: 113 NPNKELHVGHLRNIALGDAIARILAYAGREVLVLNYIDDTGRQ-----AAETLF-ALRHY 166 Query: 314 GFKPWKITYSSDYFDELYRLAEVLIKNGKAYVCHCTAEEIKRGRGIKED 362 G W D+F G+AYV E +R + E+ Sbjct: 167 GLT-WDGKEKYDHF------------AGRAYVRLHQDPEYERLQPAIEE 202 >4ARC-A nrPDB Length = 880 Score = 35.2 bits (79), Expect = 0.13, Method: Composition-based stats. Identities = 28/130 (21%), Positives = 45/130 (34%), Gaps = 27/130 (20%) Query: 242 KEHLEVTGGKVRTRF-----PPEPNGYLHIGHSKAIMVNFGYAKYHN--GTCYLR----- 289 K EVT + + ++ P P+G LH+GH + + A+Y G L+ Sbjct: 41 KRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWD 100 Query: 290 -----------FDDTNPEKEAPEYFESIKRMVSWLGFKPWKITYSSDYFDELYRLAE--- 335 ++T P + +K + LGF + E YR + Sbjct: 101 AFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFF 160 Query: 336 -VLIKNGKAY 344 L K G Y Sbjct: 161 TELYKKGLVY 170 >5AH5-A nrPDB Length = 822 Score = 34.4 bits (77), Expect = 0.18, Method: Composition-based stats. Identities = 28/133 (21%), Positives = 45/133 (33%), Gaps = 49/133 (36%) Query: 258 PEPNGYLHIGHSK-----------------AIMVNFGY----------AKYHNGTCYLRF 290 P +G+LHIGH + +++ G+ A+ Sbjct: 40 PYTSGHLHIGHVRNYSMGDTLARMQIARGYSVLHPMGWDSFGLPAENAARKFG------- 92 Query: 291 DDTNPEKEAPEYFESIKRMVSWLGFK-----------PWKITYSSDYFDELYRLAEVLIK 339 T+P K + +S+KR + LGF P + F +LYR + LI Sbjct: 93 --THPAKFTQDAIDSMKRSMMQLGFGYSWANELATCSPTYVLAQQKLFLDLYR--KGLIY 148 Query: 340 NGKAYVCHCTAEE 352 YV E+ Sbjct: 149 RDDTYVYWDPVEQ 161 >3GWQ-A nrPDB Length = 426 Score = 33.2 bits (74), Expect = 0.40, Method: Composition-based stats. Identities = 20/99 (20%), Positives = 40/99 (40%), Gaps = 4/99 (4%) Query: 55 VHNLASFVKGTDLPKSELIVNGIINGD--LKTSLQVDAAFKYVKANGEASTKMGMNENSG 112 V L F K + L+ G+ G ++ + Q +A + + + G+ G Sbjct: 153 VEQLGEFFKSVNKQLQVLLELGVPGGRTGVRDAAQRNAVLEAITRYPDTLKLAGVELYEG 212 Query: 113 VGIEITEDQVRNYVMQYIQENKERILTERYKLVPGIFAD 151 V E E +VR ++ + +E + ER+ P + + Sbjct: 213 VLKE--EHEVREFLQSAVAVTRELVEQERFARAPAVLSG 249 >3JXE-A nrPDB Length = 392 Score = 33.2 bits (74), Expect = 0.49, Method: Composition-based stats. Identities = 21/95 (22%), Positives = 40/95 (42%), Gaps = 19/95 (20%) Query: 260 PNGYLHIGHSKAIMVNFGYAKYHNGTC--YLRFDDTNPEK-----------EAPEYFESI 306 P+G +HIGH ++ F K+ L T+ EK +++I Sbjct: 82 PSGPMHIGH----IIPFFATKWLQEKFGVNLYIQITDDEKFLFKENLTFDDTKRWAYDNI 137 Query: 307 KRMVSWLGFKPWK-ITYSSDYFDELYRLAEVLIKN 340 +++ +GF P K + + F ++Y +A + K Sbjct: 138 LDIIA-VGFDPDKTFIFQNSEFTKIYEMAIPIAKK 171 >2ZUE-A nrPDB Length = 629 Score = 32.1 bits (71), Expect = 0.92, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 32/85 (37%), Gaps = 16/85 (18%) Query: 259 EPNGYLHIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKRMVSWLGFKPW 318 P LH+GH++ ++ A+ LRF Y ++ + LG + Sbjct: 129 NPTKPLHMGHARNAILGDVMAR------ILRF---------LGYEVEVQNYIDDLGIQFA 173 Query: 319 KITYSSDYF-DELYRLAEVLIKNGK 342 ++ + +E R+ L + G Sbjct: 174 QVYWGYLRLKEEFERIMNELRERGL 198 >3L9X-A nrPDB Length = 413 Score = 31.7 bits (70), Expect = 1.5, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 33/92 (35%), Gaps = 14/92 (15%) Query: 265 HIGHSKAIMVNFGYAKYHNGTCYLRFDDTNPEKEAPEYFESIKR----MVSWLGFKPWKI 320 H H + I A+ + Y+R EK E FE + + LG P++ Sbjct: 92 HFPHLQII------ARARDVDHYIRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEA 145 Query: 321 TYSSDYFDELYRLAEVLIKNGKAYVCHCTAEE 352 +D F R +++ A V + T Sbjct: 146 RERADVF---RRFNIQMVEE-MAMVENDTKAR 173 >5JVL-A nrPDB Length = 874 Score = 31.3 bits (69), Expect = 1.9, Method: Composition-based stats. Identities = 28/153 (18%), Positives = 58/153 (37%), Gaps = 12/153 (7%) Query: 17 EDKKVKEIVKN-KKVSDSLYKLIKETPSDYQWNKSTRAL--VHNLASFVKGTDLPKSELI 73 D+++K + K V+ K+ + YQ + + L ++ D P E + Sbjct: 570 SDERIKAVRKMIMAVTPEQRKVALDLLLPYQRSDFEGIFRAMDGLPVTIRLLDPPLHEFL 629 Query: 74 VNG----IING-DLKTSLQVDAAFKYVKANGEASTKMGMNENSGVGI---EITEDQVRNY 125 G I+N + T + D + ++ E + +G +GI E+TE QVR Sbjct: 630 PEGDLEHIVNELAVDTGMSADEIYSKIENLSEVNPMLGF-RGCRLGISYPELTEMQVRAI 688 Query: 126 VMQYIQENKERILTERYKLVPGIFADVKNLKEL 158 + + + +VP + + ++ Sbjct: 689 FQAAVSMTNQGVTVIPEIMVPLVGTPQELRHQI 721 >3DFY-A nrPDB Length = 345 Score = 30.5 bits (67), Expect = 2.6, Method: Composition-based stats. Identities = 39/156 (25%), Positives = 61/156 (39%), Gaps = 16/156 (10%) Query: 95 VKANGEASTKMGMNENSGVGIEITEDQVRNYVMQYIQENKERILTERYKLVPGIFADVKN 154 VK GEAS +N + E+ VR + N RI +++ +F Sbjct: 43 VKGYGEASPSFRVNGERVEALLAIENAVREMITGIDVRNYARI----FEITDRLFGFPSL 98 Query: 155 LKELKWADPRSFKPIIDQEVLKLLGPKDERDLIKKKTKNNEKKKTNSAKKSSDNSASSGP 214 +++A + + +V LLG K RD I + + +N Sbjct: 99 KAAVQFATLDALSQELGTQVCYLLGGK--RDEI--------ETDKTVGIDTVENRVKEAK 148 Query: 215 KRTMFNEGFLGDLHKVGENPQAYPELMKEHLEVTGG 250 K +F EGF KVGEN + E ++E +VT G Sbjct: 149 K--IFEEGFRVIKIKVGENLKEDIEAVEEIAKVTRG 182 >1CT9-A nrPDB Length = 553 Score = 30.5 bits (67), Expect = 3.1, Method: Composition-based stats. Identities = 11/62 (17%), Positives = 22/62 (35%), Gaps = 3/62 (4%) Query: 609 PFTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIKVSHTVSFKSLEK---DEAGKIIRIH 665 P + + Y+ R F E P P + + + K D +G+ + +H Sbjct: 489 PTSKEAYLYREIFEELFPLPSAAECVPGGPSVACSSAKAIEWDEAFKKMDDPSGRAVGVH 548 Query: 666 VN 667 + Sbjct: 549 QS 550 >4QRE-A nrPDB Length = 547 Score = 30.2 bits (66), Expect = 3.8, Method: Composition-based stats. Identities = 20/105 (19%), Positives = 34/105 (32%), Gaps = 20/105 (19%) Query: 260 PNGYLHIGHSKAIMVNFGYAK--YHNGTCYLRFDDTNPE------------KEAPEYFES 305 P+G LHIGH+ + + A+ G T+ K EY + Sbjct: 42 PSGNLHIGHAYSTVAGDVIARYKRMQGYDVRYLTGTDEHGQKIQEKAQKAGKTEIEYLDE 101 Query: 306 IKRMVS--WLGFK---PWKITYSSDYFDELYRLA-EVLIKNGKAY 344 + + W + I + + + E L+K G Y Sbjct: 102 MIAGIKQLWAKLEISNDDFIRTTEERHKHVVEQVFERLLKQGDIY 146 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.306 0.123 0.314 Lambda K H 0.267 0.0375 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,319,400 Number of Sequences: 36641 Number of extensions: 1151626 Number of successful extensions: 3731 Number of sequences better than 10.0: 36 Number of HSP's better than 10.0 without gapping: 53 Number of HSP's successfully gapped in prelim test: 24 Number of HSP's that attempted gapping in prelim test: 3497 Number of HSP's gapped (non-prelim): 90 length of query: 809 length of database: 10,336,785 effective HSP length: 105 effective length of query: 704 effective length of database: 6,489,480 effective search space: 4568593920 effective search space used: 4568593920 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 63 (29.0 bits)