BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P13035 (501 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2R46-A nrPDB 1035 0.0 3DA1-A nrPDB 174 8e-44 2RGH-A nrPDB 163 2e-40 2RGO-A nrPDB 142 3e-34 5EZ7-A nrPDB 42 6e-04 2BXR-A nrPDB 35 0.072 3HDH-A nrPDB 33 0.19 1F14-A nrPDB 33 0.21 1O5W-A nrPDB 32 0.65 4USR-A nrPDB 31 1.0 4N9X-A nrPDB 31 1.0 4K22-A nrPDB 31 1.1 3SM8-A nrPDB 30 1.6 3ATQ-A nrPDB 30 1.7 2VVL-G nrPDB 30 1.8 5LNK-k nrPDB 30 2.1 2EQ6-A nrPDB 30 2.2 4EMJ-A nrPDB 30 2.7 6NEQ-o nrPDB 30 3.2 6MEL-B nrPDB 29 3.7 3ABT-A nrPDB 29 3.8 5AJ4-Ao nrPDB 29 4.7 3KYB-A nrPDB 29 4.9 5L3D-A nrPDB 29 5.2 1MIW-A nrPDB 29 5.3 3LOV-A nrPDB 28 6.5 6CR0-A nrPDB 28 6.5 5AJ3-o nrPDB 28 6.6 2R9Z-A nrPDB 28 6.6 3RHA-A nrPDB 28 6.7 3KVE-A nrPDB 28 7.3 4PZE-A nrPDB 28 8.7 4B1B-A nrPDB 28 9.5 >2R46-A nrPDB Length = 501 Score = 1035 bits (2677), Expect = 0.0, Method: Compositional matrix adjust. Identities = 501/501 (100%), Positives = 501/501 (100%) Query: 1 METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYE 60 METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYE Sbjct: 1 METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYE 60 Query: 61 FRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKRTSLPGS 120 FRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKRTSLPGS Sbjct: 61 FRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKRTSLPGS 120 Query: 121 TGLRFGANSVLKPEIKRGFEYSDCWVDDARLVLANAQMVVRKGGEVLTRTRATSARRENG 180 TGLRFGANSVLKPEIKRGFEYSDCWVDDARLVLANAQMVVRKGGEVLTRTRATSARRENG Sbjct: 121 TGLRFGANSVLKPEIKRGFEYSDCWVDDARLVLANAQMVVRKGGEVLTRTRATSARRENG 180 Query: 181 LWIVEAEDIDTGKKYSWQARGLVNATGPWVKQFFDDGMHLPSPYGIRLIKGSHIVVPRVH 240 LWIVEAEDIDTGKKYSWQARGLVNATGPWVKQFFDDGMHLPSPYGIRLIKGSHIVVPRVH Sbjct: 181 LWIVEAEDIDTGKKYSWQARGLVNATGPWVKQFFDDGMHLPSPYGIRLIKGSHIVVPRVH 240 Query: 241 TQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYKGDPKAVKIEESEINYLLNVYNTHF 300 TQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYKGDPKAVKIEESEINYLLNVYNTHF Sbjct: 241 TQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYKGDPKAVKIEESEINYLLNVYNTHF 300 Query: 301 KKQLSRDDIVWTYSGVRPLCDDESDSPQAITRDYTLDIHDENGKAPLLSVFGGKLTTYRK 360 KKQLSRDDIVWTYSGVRPLCDDESDSPQAITRDYTLDIHDENGKAPLLSVFGGKLTTYRK Sbjct: 301 KKQLSRDDIVWTYSGVRPLCDDESDSPQAITRDYTLDIHDENGKAPLLSVFGGKLTTYRK 360 Query: 361 LAEHALEKLTPYYQGIGPAWTKESVLPGGAIEGDRDDYAARLRRRYPFLTESLARHYART 420 LAEHALEKLTPYYQGIGPAWTKESVLPGGAIEGDRDDYAARLRRRYPFLTESLARHYART Sbjct: 361 LAEHALEKLTPYYQGIGPAWTKESVLPGGAIEGDRDDYAARLRRRYPFLTESLARHYART 420 Query: 421 YGSNSELLLGNAGTVSDLGEDFGHEFYEAELKYLVDHEWVRRADDALWRRTKQGMWLNAD 480 YGSNSELLLGNAGTVSDLGEDFGHEFYEAELKYLVDHEWVRRADDALWRRTKQGMWLNAD Sbjct: 421 YGSNSELLLGNAGTVSDLGEDFGHEFYEAELKYLVDHEWVRRADDALWRRTKQGMWLNAD 480 Query: 481 QQSRVSQWLVEYTQQRLSLAS 501 QQSRVSQWLVEYTQQRLSLAS Sbjct: 481 QQSRVSQWLVEYTQQRLSLAS 501 >3DA1-A nrPDB Length = 561 Score = 174 bits (441), Expect = 8e-44, Method: Compositional matrix adjust. Identities = 164/502 (32%), Positives = 246/502 (49%), Gaps = 31/502 (6%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYEFRLV 64 DL+VIGGGI GAGIA DA RG+ ++E D A TSS S+KL+HGGLRYL+ +E +LV Sbjct: 20 DLLVIGGGITGAGIALDAQVRGIQTGLVEMNDFASGTSSRSTKLVHGGLRYLKQFEIKLV 79 Query: 65 SEALAEREVLLKMAPHIAFPMRFRLP-HRPHLRPAWMIRIGLFMYDHLG------KRTSL 117 +E ER ++ + APH+ P LP + + +GL +YD+L +R L Sbjct: 80 AEVGKERAIVYENAPHVTTPEWMLLPIFKDGTFGKFSTSLGLKVYDYLADVRKDERRYML 139 Query: 118 PGSTGLRFGANSVLKPE-IKRGFEYSDCWVDDARLVLANAQMVVRKGGEVLTRTRATSAR 176 L +L+ E +K G Y + DDARL L + V +G L + S Sbjct: 140 NEKQTLE--KEPLLRKENLKGGGIYVEYRTDDARLTLEIMKEAVARGAVALNYMKVESFI 197 Query: 177 RENGLWI-VEAEDIDTGKKYSWQARGLVNATGPWVKQFFDDGMHLPSPYGIRLIKGSHIV 235 + G + V A+D T ++ A+ +VNA GPWV + Y ++L KG H+V Sbjct: 198 YDQGKVVGVVAKDRLTDTTHTIYAKKVVNAAGPWVDTLREKDRSKHGKY-LKLSKGVHLV 256 Query: 236 V--PRVHTQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYKGDPKAVKIEESEINYLL 293 V R ++ Y D R++F IP + + IGTTD Y D + ++ + +Y+L Sbjct: 257 VDQSRFPLRQAVYFDTESDGRMIFAIPREGK-TYIGTTDTFYDKDIASPRMTVEDRDYIL 315 Query: 294 NVYNTHFKK-QLSRDDIVWTYSGVRPLCDDESDSPQAITRDYTLDIHDENGKAPLLSVFG 352 N F +L+ DD+ +++G+RPL +E I+R + D + L+S+ G Sbjct: 316 AAANYMFPSLRLTADDVESSWAGLRPLIHEEGKKASEISRKDEIFFSD----SGLISIAG 371 Query: 353 GKLTTYRKLAEHALEKLTPYYQGIGPAWTKESVLPGGAIEGDRD-----DYAARLRRRYP 407 GKLT YRK+AE ++ + P T L GG EG + D A+R + Sbjct: 372 GKLTGYRKMAERTVDAVAQGLNVNEPCTTAAIRLSGGLAEGAQGFPRFLDEASRKGAKLG 431 Query: 408 FLTESLARHYARTYGSNSELLLGNAGTVSDLGEDFG-HEFYEAELKYLVDHEWVRRADDA 466 F + + R A+ YGSN + +L A + E +G +L+Y V+ E V D Sbjct: 432 FDADEV-RRLAKLYGSNVDHVLNYAYEGKEEAEHYGLPALLLGQLQYGVEQEMVATPLDF 490 Query: 467 LWRRTKQGMWLNADQQSRVSQW 488 RRT ++ N S V QW Sbjct: 491 FVRRTG-ALFFNI---SLVHQW 508 >2RGH-A nrPDB Length = 571 Score = 163 bits (412), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 142/497 (28%), Positives = 245/497 (49%), Gaps = 47/497 (9%) Query: 26 GLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPHIAFPM 85 G+ ++E QD A TSS S+KL+HGG+RYL+ ++ +V++ + ER V+ +APHI P Sbjct: 55 GIKTGLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQGIAPHIPKPD 114 Query: 86 RFRLP----HRPHLRPAWMIRIGLFMYDHLGKRTSLPGSTGLRFGANSVLKPE------- 134 LP + +++ + +YD L TG ++ N L PE Sbjct: 115 PMLLPIYEDEGATTFNMFSVKVAMDLYDKLA------NVTGTKY-ENYTLTPEEVLEREP 167 Query: 135 --IKRGFEYSDCWVD----DARLVLANAQMVVRKGGEVLTRTRATSARRENGLWI-VEAE 187 K G + + ++D DARLV+ N + G ++++ +A E + V+A Sbjct: 168 FLKKEGLKGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYEGDQIVGVKAR 227 Query: 188 DIDTGKKYSWQARGLVNATGPWVKQFFDDGMHLPSPYGIRLIKGSHIVV--PRVHTQKQA 245 D+ T + +A+ ++N +GPWV + + P +R KG H+VV ++ + Sbjct: 228 DLLTDEVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPT 287 Query: 246 YI-LQNEDKRIVFVIPWMDEFSIIGTTDVEYKGDPKAVKIEESEINYLLNVYNTHF-KKQ 303 Y +D R+VF IP ++ + GTTD +Y+GD K+ + +++YLL+V N + + Sbjct: 288 YFDTGKQDGRMVFAIPRENK-TYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEAN 346 Query: 304 LSRDDIVWTYSGVRPLCDDESDSPQAITRDYTLDIHDENGKAPLLSVFGGKLTTYRKLAE 363 ++ DI +++G+RPL S SP I+R +L+ + +G LL++ GGK+T YRK+AE Sbjct: 347 ITLADIEASWAGLRPLLIGNSGSPSTISRGSSLE-REPDG---LLTLSGGKITDYRKMAE 402 Query: 364 HAL---EKLTPYYQGIGPAW--TKESVLPGGAIEGDR-DDYAARLRRR--YPFLTESLAR 415 AL +L GI +K+ + GG + + ++ L + L E A Sbjct: 403 GALRLIRQLLKEEYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDAT 462 Query: 416 HYARTYGSNSELLLGNAGTVSDLGEDFGHEFYE-AELKYLVDHEWVRRADDALWRRTKQG 474 + A YG+N+ + A ++ G E A L+Y ++ E V D L RRT Sbjct: 463 YIADFYGTNARRIFELA---KEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNH- 518 Query: 475 MWLNADQQSRVSQWLVE 491 + DQ + Q +++ Sbjct: 519 LLFERDQLDEIKQPVID 535 >2RGO-A nrPDB Length = 607 Score = 142 bits (358), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 146/543 (26%), Positives = 248/543 (45%), Gaps = 89/543 (16%) Query: 26 GLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPHIAFPM 85 G+ ++E QD A TSS S+KL+HGG+RYL+ ++ +V++ + ER V+ +APHI P Sbjct: 41 GIKTGLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQGIAPHIPKPD 100 Query: 86 RFRLP----HRPHLRPAWMIRIGLFMYDHLGKRTSLPGSTGLRFGANSVLKPE------- 134 LP + +++ + +YD L TG ++ N L PE Sbjct: 101 PMLLPIYEDEGATTFNMFSVKVAMDLYDKLA------NVTGTKY-ENYTLTPEEVLEREP 153 Query: 135 --IKRGFEYSDCWVD----DARLVLANAQMVVRKGGEVLTRTRATSARRENGLWI-VEAE 187 K G + + ++D DARLV+ N + G ++++ +A E + V+A Sbjct: 154 FLKKEGLKGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYEGDQIVGVKAR 213 Query: 188 DIDTGKKYSWQARGLVNATGPWVKQFFDDGMHLPSPYGIRLIKGSHIVVPRVH---TQKQ 244 D+ T + +A+ ++N +GPWV + + P +R KG H+VV Q Sbjct: 214 DLLTDEVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPT 273 Query: 245 AYILQNEDKRIVFVIPWMDEFSIIGTTDVEYKGDPKAVKIEESEINYLLNVYNTHF-KKQ 303 + +D R+VF IP ++ + GTTD +Y+GD K+ + +++YLL+V N + + Sbjct: 274 YFDTGKQDGRMVFAIPRENK-TYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEAN 332 Query: 304 LSRDDIVWTYSGVRPLC-----------DDESDSPQA---------------ITRDYTLD 337 ++ DI +++G+RPL D+ S S ++ ++R D Sbjct: 333 ITLADIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED 392 Query: 338 I--HDENG---KAP---------------LLSVFGGKLTTYRKLAEHAL---EKLTPYYQ 374 + H EN KAP LL++ GGK+T YRK+AE AL +L Sbjct: 393 VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKEEY 452 Query: 375 GIGPAW--TKESVLPGGAIEGDR-DDYAARLRRR--YPFLTESLARHYARTYGSNSELLL 429 GI +K+ + GG + + ++ L + L E A + A YG+N+ + Sbjct: 453 GIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNARRIF 512 Query: 430 GNAGTVSDLGEDFGHEFYE-AELKYLVDHEWVRRADDALWRRTKQGMWLNADQQSRVSQW 488 A ++ G E A L+Y ++ E V D L RRT + DQ + Q Sbjct: 513 ELA---KEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNH-LLFERDQLDEIKQP 568 Query: 489 LVE 491 +++ Sbjct: 569 VID 571 >5EZ7-A nrPDB Length = 392 Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 37/68 (54%) Query: 3 TKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYEFR 62 + D++++GGGI G + A G + +++E+ L S S +IHGG +Y H Sbjct: 7 STDILIVGGGIAGLWLNARLRRAGYATVLVESASLGGGQSVKSQGIIHGGAKYALHGALT 66 Query: 63 LVSEALAE 70 SEA+A+ Sbjct: 67 GASEAIAD 74 >2BXR-A nrPDB Length = 527 Score = 35.0 bits (79), Expect = 0.072, Method: Compositional matrix adjust. Identities = 17/32 (53%), Positives = 23/32 (71%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQD 36 D++VIGGGI+G A G+SVL+LEA+D Sbjct: 15 DVVVIGGGISGLSAAKLLTEYGVSVLVLEARD 46 >3HDH-A nrPDB Length = 302 Score = 33.5 bits (75), Expect = 0.19, Method: Compositional matrix adjust. Identities = 22/58 (37%), Positives = 32/58 (55%), Gaps = 3/58 (5%) Query: 4 KDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYEF 61 K + VIGGG+ GAGIA AA G +V++++ + A S K I LR + +F Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILA---KSKKGIEESLRKVAKKKF 70 >1F14-A nrPDB Length = 310 Score = 33.5 bits (75), Expect = 0.21, Method: Compositional matrix adjust. Identities = 22/58 (37%), Positives = 32/58 (55%), Gaps = 3/58 (5%) Query: 4 KDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYEF 61 K + VIGGG+ GAGIA AA G +V++++ + A S K I LR + +F Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILA---KSKKGIEESLRKVAKKKF 70 >1O5W-A nrPDB Length = 534 Score = 32.0 bits (71), Expect = 0.65, Method: Compositional matrix adjust. Identities = 15/32 (46%), Positives = 23/32 (71%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQD 36 D++VIGGGI+G A + ++VL+LEA+D Sbjct: 23 DVVVIGGGISGLAAAKLLSEYKINVLVLEARD 54 >4USR-A nrPDB Length = 361 Score = 31.2 bits (69), Expect = 1.0, Method: Compositional matrix adjust. Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 12/64 (18%) Query: 171 RATSARRENGLWIVEAEDIDTGKKYSWQARGLVNATGPWVKQFFDDGMHLPSPYGIRLIK 230 R + R + LW V+A D W AR +++ATG W K F +P G L + Sbjct: 103 RVDTVTRLDDLWRVQAGD------QQWLARAVISATGTWSKPF------IPPYEGRELFQ 150 Query: 231 GSHI 234 G+ I Sbjct: 151 GAQI 154 >4N9X-A nrPDB Length = 411 Score = 31.2 bits (69), Expect = 1.0, Method: Compositional matrix adjust. Identities = 13/35 (37%), Positives = 22/35 (62%) Query: 1 METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQ 35 M++ D+++ GGG+ G +A G GL + +LE Q Sbjct: 1 MQSFDVVIAGGGMVGLALACGLQGSGLRIAVLEKQ 35 >4K22-A nrPDB Length = 365 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 13/33 (39%), Positives = 21/33 (63%) Query: 1 METKDLIVIGGGINGAGIAADAAGRGLSVLMLE 33 M++ D+ ++GGG+ G +A G GL V +LE Sbjct: 1 MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLE 33 >3SM8-A nrPDB Length = 381 Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust. Identities = 20/52 (38%), Positives = 25/52 (48%), Gaps = 6/52 (11%) Query: 159 VVRKGGEVLTRTRATSARRENGLWIVEAEDIDTGKKYSWQARGLVNATGPWV 210 + R G+VL A RR +G W V D G S++A LVNA G W Sbjct: 164 IRRNQGQVLCNHEALEIRRVDGAWEVR---CDAG---SYRAAVLVNAAGAWC 209 >3ATQ-A nrPDB Length = 453 Score = 30.4 bits (67), Expect = 1.7, Method: Compositional matrix adjust. Identities = 15/57 (26%), Positives = 30/57 (52%), Gaps = 6/57 (10%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQ------DLACATSSASSKLIHGGLRY 55 D+++IGGG G+ A + RGL +L+++++ D C + + + G+ Y Sbjct: 8 DVLIIGGGFAGSSAAYQLSRRGLKILLVDSKPWNRIGDKPCGDAVSKAHFDKLGMPY 64 >2VVL-G nrPDB Length = 495 Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust. Identities = 15/32 (46%), Positives = 18/32 (56%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQD 36 D+IVIGGG G D G L+LEA+D Sbjct: 41 DVIVIGGGYCGLTATRDLTVAGFKTLLLEARD 72 >5LNK-k nrPDB Length = 320 Score = 30.4 bits (67), Expect = 2.1, Method: Compositional matrix adjust. Identities = 34/123 (27%), Positives = 52/123 (42%), Gaps = 14/123 (11%) Query: 273 VEYKGDPKAVKIEESEINYLLNVYNTHFKKQLSRDDIVWTYSGVRPLCDDESDSPQAITR 332 ++ KG+P +KI + + + NVY F ++S V YS E++ + + Sbjct: 183 IQKKGNPHEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAW------EAEDAEKVVE 236 Query: 333 DYTLDIHDENGKAPLLSVFGGKLTTYRKLAEHALEKLTPYYQGIGPAWTKESVLPGGAIE 392 D +D K P L KL R L + LE L Y I P + E + GA + Sbjct: 237 DIQYLKYD---KGPWLDQDDRKLHNLRMLVQDKLEVLN--YTSI-PVFLPEVTI--GAHQ 288 Query: 393 GDR 395 DR Sbjct: 289 SDR 291 >2EQ6-A nrPDB Length = 464 Score = 30.0 bits (66), Expect = 2.2, Method: Compositional matrix adjust. Identities = 19/38 (50%), Positives = 23/38 (60%) Query: 1 METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLA 38 M+T DLIVIG G G A AA GL VL +EA ++ Sbjct: 4 MKTYDLIVIGTGPGGYHAAIRAAQLGLKVLAVEAGEVG 41 >4EMJ-A nrPDB Length = 410 Score = 30.0 bits (66), Expect = 2.7, Method: Compositional matrix adjust. Identities = 15/31 (48%), Positives = 21/31 (67%) Query: 6 LIVIGGGINGAGIAADAAGRGLSVLMLEAQD 36 L+++GGG+ G +A A GLSV +LEA D Sbjct: 146 LLIVGGGLIGCEVATTARKLGLSVTILEAGD 176 >6NEQ-o nrPDB Length = 575 Score = 29.6 bits (65), Expect = 3.2, Method: Compositional matrix adjust. Identities = 23/103 (22%), Positives = 45/103 (43%), Gaps = 5/103 (4%) Query: 212 QFFDDGMHLPSPYGIRLIKGSHIVVPRVHTQKQAYILQ---NEDKRIVFVIPW--MDEFS 266 +F+ +P G + +V+P+ T + +LQ + R P+ D+ Sbjct: 35 RFYSGSAAVPKDEGADIAGTEEVVIPKKKTWDKVAVLQALASTVHRDTTAAPYAFQDDPY 94 Query: 267 IIGTTDVEYKGDPKAVKIEESEINYLLNVYNTHFKKQLSRDDI 309 +I T+ VE A K E+ +++N Y +F+K ++ I Sbjct: 95 LIPTSSVESHSFLLAKKSGENAAKFIINSYPKYFQKDIAEPHI 137 >6MEL-B nrPDB Length = 387 Score = 29.3 bits (64), Expect = 3.7, Method: Compositional matrix adjust. Identities = 13/47 (27%), Positives = 25/47 (53%), Gaps = 3/47 (6%) Query: 310 VWTYSGVRP---LCDDESDSPQAITRDYTLDIHDENGKAPLLSVFGG 353 + YSG +P L SP+ + + + + + D+N K +++FGG Sbjct: 275 IINYSGAKPANFLDVGGGASPETVAKAFEIILRDKNVKVIFINIFGG 321 >3ABT-A nrPDB Length = 662 Score = 29.3 bits (64), Expect = 3.8, Method: Compositional matrix adjust. Identities = 13/35 (37%), Positives = 21/35 (60%) Query: 2 ETKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQD 36 +T +I+IG G++G A G+ V +LEA+D Sbjct: 106 KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARD 140 >5AJ4-Ao nrPDB Length = 530 Score = 29.3 bits (64), Expect = 4.7, Method: Compositional matrix adjust. Identities = 24/103 (23%), Positives = 45/103 (43%), Gaps = 5/103 (4%) Query: 212 QFFDDGMHLPSPYGIRLIKGSHIVVPRVHTQKQAYILQ---NEDKRIVFVIPWM--DEFS 266 +F+ P G + +V+P+ T + ILQ + R P++ D+ Sbjct: 35 RFYSGSAAHPEVEGANVTGIEEVVIPKKKTWDKVAILQALASTVHRDSTAAPYVFQDDPY 94 Query: 267 IIGTTDVEYKGDPKAVKIEESEINYLLNVYNTHFKKQLSRDDI 309 +I T+ VE A K E+ +++N Y +F+K ++ I Sbjct: 95 LIPTSSVESHSFLLAKKSGENAAKFIINSYPKYFQKDIAEPHI 137 >3KYB-A nrPDB Length = 390 Score = 28.9 bits (63), Expect = 4.9, Method: Compositional matrix adjust. Identities = 11/36 (30%), Positives = 23/36 (63%) Query: 1 METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQD 36 M++K ++++G G +GA I A +G V +++ +D Sbjct: 1 MKSKKILIVGAGFSGAVIGRQLAEKGHQVHIIDQRD 36 >5L3D-A nrPDB Length = 852 Score = 28.9 bits (63), Expect = 5.2, Method: Compositional matrix adjust. Identities = 13/35 (37%), Positives = 21/35 (60%) Query: 2 ETKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQD 36 +T +I+IG G++G A G+ V +LEA+D Sbjct: 277 KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARD 311 >1MIW-A nrPDB Length = 404 Score = 28.9 bits (63), Expect = 5.3, Method: Compositional matrix adjust. Identities = 14/38 (36%), Positives = 21/38 (55%), Gaps = 2/38 (5%) Query: 459 WVRRADDALWRRTKQGMWLNADQQSRVSQWLVEYTQQR 496 WV+ A DA+WR G N ++ R+ WL+E + R Sbjct: 365 WVKEALDAIWRAVVNGEVEN--EKERIYAWLMERNRTR 400 >3LOV-A nrPDB Length = 475 Score = 28.5 bits (62), Expect = 6.5, Method: Compositional matrix adjust. Identities = 15/36 (41%), Positives = 23/36 (63%), Gaps = 2/36 (5%) Query: 1 METKDLIVIGGGINGAGIA--ADAAGRGLSVLMLEA 34 M +K L+++GGGI G A A+ A L++ +LEA Sbjct: 2 MSSKRLVIVGGGITGLAAAYYAERAFPDLNITLLEA 37 >6CR0-A nrPDB Length = 440 Score = 28.5 bits (62), Expect = 6.5, Method: Compositional matrix adjust. Identities = 13/31 (41%), Positives = 21/31 (67%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQ 35 D IV+G G +G A + + +G SVL++EA+ Sbjct: 10 DAIVVGAGFSGLVAARELSAQGRSVLIIEAR 40 >5AJ3-o nrPDB Length = 692 Score = 28.5 bits (62), Expect = 6.6, Method: Compositional matrix adjust. Identities = 24/103 (23%), Positives = 45/103 (43%), Gaps = 5/103 (4%) Query: 212 QFFDDGMHLPSPYGIRLIKGSHIVVPRVHTQKQAYILQ---NEDKRIVFVIPWM--DEFS 266 +F+ P G + +V+P+ T + ILQ + R P++ D+ Sbjct: 35 RFYSGSAAHPEVEGANVTGIEEVVIPKKKTWDKVAILQALASTVHRDSTAAPYVFQDDPY 94 Query: 267 IIGTTDVEYKGDPKAVKIEESEINYLLNVYNTHFKKQLSRDDI 309 +I T+ VE A K E+ +++N Y +F+K ++ I Sbjct: 95 LIPTSSVESHSFLLAKKSGENAAKFIINSYPKYFQKDIAEPHI 137 >2R9Z-A nrPDB Length = 463 Score = 28.5 bits (62), Expect = 6.6, Method: Compositional matrix adjust. Identities = 15/33 (45%), Positives = 20/33 (60%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQDL 37 DLI IGGG G +A AA G V ++E++ L Sbjct: 6 DLIAIGGGSGGLAVAEKAAAFGKRVALIESKAL 38 >3RHA-A nrPDB Length = 482 Score = 28.5 bits (62), Expect = 6.7, Method: Compositional matrix adjust. Identities = 13/33 (39%), Positives = 22/33 (66%) Query: 4 KDLIVIGGGINGAGIAADAAGRGLSVLMLEAQD 36 +D++++G G +G A + GLSV +LEA+D Sbjct: 8 RDVVIVGAGPSGLTAARELKKAGLSVAVLEARD 40 >3KVE-A nrPDB Length = 486 Score = 28.5 bits (62), Expect = 7.3, Method: Compositional matrix adjust. Identities = 14/35 (40%), Positives = 21/35 (60%) Query: 4 KDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLA 38 K ++V+G G++G A AG G V +LEA + A Sbjct: 34 KHVVVVGAGMSGLSAAYVLAGAGHKVTVLEASERA 68 >4PZE-A nrPDB Length = 284 Score = 28.1 bits (61), Expect = 8.7, Method: Compositional matrix adjust. Identities = 14/38 (36%), Positives = 22/38 (57%) Query: 1 METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLA 38 M + + ++G G G GIA A GL+V+M++ D A Sbjct: 1 MSIRTVGIVGAGTMGNGIAQACAVVGLNVVMVDISDAA 38 >4B1B-A nrPDB Length = 542 Score = 28.1 bits (61), Expect = 9.5, Method: Compositional matrix adjust. Identities = 13/29 (44%), Positives = 17/29 (58%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLE 33 D +VIGGG G A +AA G VL+ + Sbjct: 44 DYVVIGGGPGGMASAKEAAAHGARVLLFD 72 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2R46-A nrPDB 769 0.0 2RGH-A nrPDB 600 e-172 3DA1-A nrPDB 585 e-167 2RGO-A nrPDB 576 e-165 5EZ7-A nrPDB 99 5e-21 Sequences not found previously or not previously below threshold: 5L46-A nrPDB 42 6e-04 3BHF-A nrPDB 40 0.002 2VVL-G nrPDB 40 0.003 4YSH-A nrPDB 40 0.003 4P9S-A nrPDB 39 0.003 2BS2-A nrPDB 39 0.004 5XMJ-A nrPDB 39 0.005 1ZOV-A nrPDB 38 0.008 2UZZ-A nrPDB 37 0.015 3SM8-A nrPDB 37 0.019 1QO8-A nrPDB 37 0.026 3ATQ-A nrPDB 36 0.045 6MEL-B nrPDB 35 0.053 4K22-A nrPDB 35 0.054 2YVG-A nrPDB 35 0.091 2BXR-A nrPDB 35 0.099 4DGK-A nrPDB 34 0.17 1KQY-A nrPDB 34 0.23 6CMZ-A nrPDB 33 0.29 1NG3-A nrPDB 33 0.34 3NK2-X nrPDB 33 0.35 2R9Z-A nrPDB 33 0.37 6BRD-A nrPDB 33 0.38 3URH-A nrPDB 33 0.41 2IVE-A nrPDB 32 0.42 4ZN0-A nrPDB 32 0.45 4EIQ-A nrPDB 32 0.47 5KOX-A nrPDB 32 0.49 5A3F-A nrPDB 32 0.49 2EQ6-A nrPDB 32 0.56 1PS9-A nrPDB 32 0.59 2YQU-A nrPDB 32 0.65 4EMJ-A nrPDB 32 0.65 1O5W-A nrPDB 32 0.69 3ABT-A nrPDB 32 0.77 6N7F-A nrPDB 31 1.00 5L3D-A nrPDB 31 1.0 3KVE-A nrPDB 31 1.2 3R9U-A nrPDB 31 1.3 1SEZ-A nrPDB 30 1.7 1V59-A nrPDB 30 1.7 3L8K-A nrPDB 30 1.8 2JB2-A nrPDB 30 1.8 4EHJ-A nrPDB 30 1.9 1EVY-A nrPDB 30 1.9 1REO-A nrPDB 30 2.0 3L43-A nrPDB 30 2.0 2NVK-X nrPDB 30 2.0 1F14-A nrPDB 30 2.0 3HDH-A nrPDB 30 2.2 4C3X-A nrPDB 30 2.2 1NEP-A nrPDB 30 2.3 3ICS-A nrPDB 30 2.4 5G3Y-A nrPDB 30 2.6 2BHU-A nrPDB 30 3.0 2CVJ-A nrPDB 30 3.1 6DLV-b nrPDB 30 3.2 1F8S-A nrPDB 30 3.5 4UUD-B nrPDB 30 3.5 3IHG-A nrPDB 29 4.1 4AP1-A nrPDB 29 4.4 5MOG-A nrPDB 29 4.4 3NIX-A nrPDB 29 4.6 1D4E-A nrPDB 29 5.1 2A87-A nrPDB 29 5.5 2AKA-B nrPDB 29 5.7 5F13-A nrPDB 29 5.8 2X2E-A nrPDB 29 6.4 4OVI-A nrPDB 28 8.1 5TWC-A nrPDB 28 8.3 >2R46-A nrPDB Length = 501 Score = 769 bits (1985), Expect = 0.0, Method: Composition-based stats. Identities = 501/501 (100%), Positives = 501/501 (100%) Query: 1 METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYE 60 METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYE Sbjct: 1 METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYE 60 Query: 61 FRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKRTSLPGS 120 FRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKRTSLPGS Sbjct: 61 FRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKRTSLPGS 120 Query: 121 TGLRFGANSVLKPEIKRGFEYSDCWVDDARLVLANAQMVVRKGGEVLTRTRATSARRENG 180 TGLRFGANSVLKPEIKRGFEYSDCWVDDARLVLANAQMVVRKGGEVLTRTRATSARRENG Sbjct: 121 TGLRFGANSVLKPEIKRGFEYSDCWVDDARLVLANAQMVVRKGGEVLTRTRATSARRENG 180 Query: 181 LWIVEAEDIDTGKKYSWQARGLVNATGPWVKQFFDDGMHLPSPYGIRLIKGSHIVVPRVH 240 LWIVEAEDIDTGKKYSWQARGLVNATGPWVKQFFDDGMHLPSPYGIRLIKGSHIVVPRVH Sbjct: 181 LWIVEAEDIDTGKKYSWQARGLVNATGPWVKQFFDDGMHLPSPYGIRLIKGSHIVVPRVH 240 Query: 241 TQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYKGDPKAVKIEESEINYLLNVYNTHF 300 TQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYKGDPKAVKIEESEINYLLNVYNTHF Sbjct: 241 TQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYKGDPKAVKIEESEINYLLNVYNTHF 300 Query: 301 KKQLSRDDIVWTYSGVRPLCDDESDSPQAITRDYTLDIHDENGKAPLLSVFGGKLTTYRK 360 KKQLSRDDIVWTYSGVRPLCDDESDSPQAITRDYTLDIHDENGKAPLLSVFGGKLTTYRK Sbjct: 301 KKQLSRDDIVWTYSGVRPLCDDESDSPQAITRDYTLDIHDENGKAPLLSVFGGKLTTYRK 360 Query: 361 LAEHALEKLTPYYQGIGPAWTKESVLPGGAIEGDRDDYAARLRRRYPFLTESLARHYART 420 LAEHALEKLTPYYQGIGPAWTKESVLPGGAIEGDRDDYAARLRRRYPFLTESLARHYART Sbjct: 361 LAEHALEKLTPYYQGIGPAWTKESVLPGGAIEGDRDDYAARLRRRYPFLTESLARHYART 420 Query: 421 YGSNSELLLGNAGTVSDLGEDFGHEFYEAELKYLVDHEWVRRADDALWRRTKQGMWLNAD 480 YGSNSELLLGNAGTVSDLGEDFGHEFYEAELKYLVDHEWVRRADDALWRRTKQGMWLNAD Sbjct: 421 YGSNSELLLGNAGTVSDLGEDFGHEFYEAELKYLVDHEWVRRADDALWRRTKQGMWLNAD 480 Query: 481 QQSRVSQWLVEYTQQRLSLAS 501 QQSRVSQWLVEYTQQRLSLAS Sbjct: 481 QQSRVSQWLVEYTQQRLSLAS 501 >2RGH-A nrPDB Length = 571 Score = 600 bits (1546), Expect = e-172, Method: Composition-based stats. Identities = 142/498 (28%), Positives = 242/498 (48%), Gaps = 47/498 (9%) Query: 25 RGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPHIAFP 84 G+ ++E QD A TSS S+KL+HGG+RYL+ ++ +V++ + ER V+ +APHI P Sbjct: 54 SGIKTGLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQGIAPHIPKP 113 Query: 85 MRFRLP----HRPHLRPAWMIRIGLFMYDHLGKRTSLPGSTGLRFGANSVLKPE------ 134 LP + +++ + +YD L TG ++ N L PE Sbjct: 114 DPMLLPIYEDEGATTFNMFSVKVAMDLYDKLA------NVTGTKY-ENYTLTPEEVLERE 166 Query: 135 ---IKRGFEYSDCWVD----DARLVLANAQMVVRKGGEVLTRTRATSARRENGLWI-VEA 186 K G + + ++D DARLV+ N + G ++++ +A E + V+A Sbjct: 167 PFLKKEGLKGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYEGDQIVGVKA 226 Query: 187 EDIDTGKKYSWQARGLVNATGPWVKQFFDDGMHLPSPYGIRLIKGSHIVVPRVH---TQK 243 D+ T + +A+ ++N +GPWV + + P +R KG H+VV Q Sbjct: 227 RDLLTDEVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQP 286 Query: 244 QAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYKGDPKAVKIEESEINYLLNVYNTHFK-K 302 + +D R+VF IP ++ + GTTD +Y+GD K+ + +++YLL+V N + Sbjct: 287 TYFDTGKQDGRMVFAIPRENK-TYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEA 345 Query: 303 QLSRDDIVWTYSGVRPLCDDESDSPQAITRDYTLDIHDENGKAPLLSVFGGKLTTYRKLA 362 ++ DI +++G+RPL S SP I+R +L+ + +G LL++ GGK+T YRK+A Sbjct: 346 NITLADIEASWAGLRPLLIGNSGSPSTISRGSSLE-REPDG---LLTLSGGKITDYRKMA 401 Query: 363 EHAL---EKLTPYYQGIGPAW--TKESVLPGGAIEGDR-DDYAARLRRR--YPFLTESLA 414 E AL +L GI +K+ + GG + + ++ L + L E A Sbjct: 402 EGALRLIRQLLKEEYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDA 461 Query: 415 RHYARTYGSNSELLLGNAGTVSDLGEDFGHEFYE-AELKYLVDHEWVRRADDALWRRTKQ 473 + A YG+N+ + A ++ G E A L+Y ++ E V D L RRT Sbjct: 462 TYIADFYGTNARRIFELA---KEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNH 518 Query: 474 GMWLNADQQSRVSQWLVE 491 + DQ + Q +++ Sbjct: 519 -LLFERDQLDEIKQPVID 535 >3DA1-A nrPDB Length = 561 Score = 585 bits (1507), Expect = e-167, Method: Composition-based stats. Identities = 164/502 (32%), Positives = 246/502 (49%), Gaps = 31/502 (6%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYEFRLV 64 DL+VIGGGI GAGIA DA RG+ ++E D A TSS S+KL+HGGLRYL+ +E +LV Sbjct: 20 DLLVIGGGITGAGIALDAQVRGIQTGLVEMNDFASGTSSRSTKLVHGGLRYLKQFEIKLV 79 Query: 65 SEALAEREVLLKMAPHIAFPMRFRLP-HRPHLRPAWMIRIGLFMYDHLG------KRTSL 117 +E ER ++ + APH+ P LP + + +GL +YD+L +R L Sbjct: 80 AEVGKERAIVYENAPHVTTPEWMLLPIFKDGTFGKFSTSLGLKVYDYLADVRKDERRYML 139 Query: 118 PGSTGLRFGANSVLKPE-IKRGFEYSDCWVDDARLVLANAQMVVRKGGEVLTRTRATSAR 176 L +L+ E +K G Y + DDARL L + V +G L + S Sbjct: 140 NEKQTLE--KEPLLRKENLKGGGIYVEYRTDDARLTLEIMKEAVARGAVALNYMKVESFI 197 Query: 177 RENGLWI-VEAEDIDTGKKYSWQARGLVNATGPWVKQFFDDGMHLPSPYGIRLIKGSHIV 235 + G + V A+D T ++ A+ +VNA GPWV + Y ++L KG H+V Sbjct: 198 YDQGKVVGVVAKDRLTDTTHTIYAKKVVNAAGPWVDTLREKDRSKHGKY-LKLSKGVHLV 256 Query: 236 VP--RVHTQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYKGDPKAVKIEESEINYLL 293 V R ++ Y D R++F IP + + IGTTD Y D + ++ + +Y+L Sbjct: 257 VDQSRFPLRQAVYFDTESDGRMIFAIPREGK-TYIGTTDTFYDKDIASPRMTVEDRDYIL 315 Query: 294 NVYNTHFKK-QLSRDDIVWTYSGVRPLCDDESDSPQAITRDYTLDIHDENGKAPLLSVFG 352 N F +L+ DD+ +++G+RPL +E I+R + D + L+S+ G Sbjct: 316 AAANYMFPSLRLTADDVESSWAGLRPLIHEEGKKASEISRKDEIFFSD----SGLISIAG 371 Query: 353 GKLTTYRKLAEHALEKLTPYYQGIGPAWTKESVLPGGAIEGDRD-----DYAARLRRRYP 407 GKLT YRK+AE ++ + P T L GG EG + D A+R + Sbjct: 372 GKLTGYRKMAERTVDAVAQGLNVNEPCTTAAIRLSGGLAEGAQGFPRFLDEASRKGAKLG 431 Query: 408 FLTESLARHYARTYGSNSELLLGNAGTVSDLGEDFG-HEFYEAELKYLVDHEWVRRADDA 466 F + + R A+ YGSN + +L A + E +G +L+Y V+ E V D Sbjct: 432 FDADEV-RRLAKLYGSNVDHVLNYAYEGKEEAEHYGLPALLLGQLQYGVEQEMVATPLDF 490 Query: 467 LWRRTKQGMWLNADQQSRVSQW 488 RRT ++ N S V QW Sbjct: 491 FVRRTG-ALFFNI---SLVHQW 508 >2RGO-A nrPDB Length = 607 Score = 576 bits (1485), Expect = e-165, Method: Composition-based stats. Identities = 142/544 (26%), Positives = 241/544 (44%), Gaps = 89/544 (16%) Query: 25 RGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPHIAFP 84 G+ ++E QD A TSS S+KL+HGG+RYL+ ++ +V++ + ER V+ +APHI P Sbjct: 40 SGIKTGLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQGIAPHIPKP 99 Query: 85 MRFRLP----HRPHLRPAWMIRIGLFMYDHLGKRTSLPGSTGLRFGANSVLKPE------ 134 LP + +++ + +YD L TG ++ N L PE Sbjct: 100 DPMLLPIYEDEGATTFNMFSVKVAMDLYDKLA------NVTGTKY-ENYTLTPEEVLERE 152 Query: 135 ---IKRGFEYSDCWVD----DARLVLANAQMVVRKGGEVLTRTRATSARRENGLWI-VEA 186 K G + + ++D DARLV+ N + G ++++ +A E + V+A Sbjct: 153 PFLKKEGLKGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYEGDQIVGVKA 212 Query: 187 EDIDTGKKYSWQARGLVNATGPWVKQFFDDGMHLPSPYGIRLIKGSHIVVPRVH---TQK 243 D+ T + +A+ ++N +GPWV + + P +R KG H+VV Q Sbjct: 213 RDLLTDEVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQP 272 Query: 244 QAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYKGDPKAVKIEESEINYLLNVYNTHFK-K 302 + +D R+VF IP ++ + GTTD +Y+GD K+ + +++YLL+V N + Sbjct: 273 TYFDTGKQDGRMVFAIPRENK-TYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEA 331 Query: 303 QLSRDDIVWTYSGVRPLCDDESDSP--------------------------QAITRDYTL 336 ++ DI +++G+RPL S S ++R Sbjct: 332 NITLADIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVE 391 Query: 337 DI--HDENGK------------------APLLSVFGGKLTTYRKLAEHAL---EKLTPYY 373 D+ H EN + LL++ GGK+T YRK+AE AL +L Sbjct: 392 DVLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKEE 451 Query: 374 QGIGPAW--TKESVLPGGAIEGDR-DDYAARLRRR--YPFLTESLARHYARTYGSNSELL 428 GI +K+ + GG + + ++ L + L E A + A YG+N+ + Sbjct: 452 YGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNARRI 511 Query: 429 LGNAGTVSDLGEDFGHEFYE-AELKYLVDHEWVRRADDALWRRTKQGMWLNADQQSRVSQ 487 A ++ G E A L+Y ++ E V D L RRT + DQ + Q Sbjct: 512 FELA---KEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNH-LLFERDQLDEIKQ 567 Query: 488 WLVE 491 +++ Sbjct: 568 PVID 571 >5EZ7-A nrPDB Length = 392 Score = 98.6 bits (244), Expect = 5e-21, Method: Composition-based stats. Identities = 22/68 (32%), Positives = 37/68 (54%) Query: 3 TKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYEFR 62 + D++++GGGI G + A G + +++E+ L S S +IHGG +Y H Sbjct: 7 STDILIVGGGIAGLWLNARLRRAGYATVLVESASLGGGQSVKSQGIIHGGAKYALHGALT 66 Query: 63 LVSEALAE 70 SEA+A+ Sbjct: 67 GASEAIAD 74 >5L46-A nrPDB Length = 841 Score = 42.0 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 54/273 (19%), Positives = 99/273 (36%), Gaps = 35/273 (12%) Query: 2 ETKDLIVIGGGINGAGIAADAAGRGLS-VLMLEAQDLACATSSASSKLI---HGGLRYLE 57 + + ++IGGG G +A A G+ V++LE +L ++ ++ L H G+ + Sbjct: 21 DRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKK 80 Query: 58 -HYEFRLVSEALAEREVLLKMAPHIAFPMRF-RLPHRPHLRPAWMIRIGLFMYDHLGKRT 115 HY+ + E L E E + H +R P R M R G H ++ Sbjct: 81 IHYDSIKLYEKL-EEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGW----HATEQY 135 Query: 116 SLPGSTGLRFGANSVLKPEIKRGFEYSDCWVDDARLVLANAQMVVRKGGEVLTRTRATSA 175 + + + + D +D L +A A + G + TS Sbjct: 136 LIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSL 195 Query: 176 R-RENGLWIVEAEDIDTGKKYSWQARGLVNATGPWVKQFFDDGMHLPSPYGIRLIKGSHI 234 + R +G W VE + S +A +VNA G W + G + + + ++ ++ Sbjct: 196 KARSDGTWDVET------PQGSMRANRIVNAAGFWA---REVGKMIGLEHPLIPVQHQYV 246 Query: 235 VVPRVH--------------TQKQAYILQNEDK 253 V + + Y+ Q D Sbjct: 247 VTSTIPEVKALKRELPVLRDLEGSYYLRQERDG 279 >3BHF-A nrPDB Length = 390 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 46/238 (19%), Positives = 81/238 (34%), Gaps = 40/238 (16%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYEFRL- 63 D+IV+G G G A +G+ L+++A D ++ HG + + H Sbjct: 6 DVIVVGAGSMGMAAGYQLAKQGVKTLLVDAFD-----PPHTNGSHHGDTKIIRHAYGEGR 60 Query: 64 --VSEALAEREVLLKMAP---HIAFPMRFRLPHRPHLRPAW-----------MIRIGLFM 107 V AL +E+ ++ H F L P A+ + + L Sbjct: 61 EYVPLALRSQELWYELEKETHHKIFTKTGVLVFGPKGESAFVAETMEAAKEHSLTVDLLE 120 Query: 108 YDHLGKRTSLPGSTGLRFGANSVLKPEIKRGFEYSDCWVDDARLVLANAQMVVRKGGEVL 167 D + KR G+ N E G +S+ + R ++ +G +VL Sbjct: 121 GDEINKRWP-----GITVPENYNAIFEPNSGVLFSENCIRAYR------ELAEARGAKVL 169 Query: 168 TRTRATSARRENGLWIVEAEDIDTGKKYSWQARGLVNATGPWVKQFFDD-GMHLPSPY 224 T TR +E + S+ A L+ + G W + + +P Sbjct: 170 THTRVEDFDISPDSVKIETAN------GSYTADKLIVSMGAWNSKLLSKLNLDIPLQP 221 >2VVL-G nrPDB Length = 495 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 17/42 (40%), Positives = 22/42 (52%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASS 46 D+IVIGGG G D G L+LEA+D S +S+ Sbjct: 41 DVIVIGGGYCGLTATRDLTVAGFKTLLLEARDRIGGRSWSSN 82 >4YSH-A nrPDB Length = 376 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 24/129 (18%), Positives = 51/129 (39%), Gaps = 12/129 (9%) Query: 196 SWQARGLVNATGPWVKQFFDDGMHLPSPYGIRLIKGSHIVVPR-VHTQKQAYILQNEDKR 254 ++ A +V A+G W + G + + +KG ++V V + +N Sbjct: 197 TFAAEAVVIASGAWAARL---GARVGLSLSVYPVKGECVMVRAPVPLLQTTVFAKNG--- 250 Query: 255 IVFVIPWMDEFSIIGTTDVEYKGDPKAVKIEESEINYLLNVYNTHFKKQLSRDDIVWTYS 314 +++P +IG T G ++ + LL+ + + + V ++S Sbjct: 251 -CYIVPKSGNRLLIGATST--PGTF-DRRVSAGGVMNLLHRAAHLVP-DIEQAEWVASWS 305 Query: 315 GVRPLCDDE 323 G+RP +D Sbjct: 306 GIRPQTEDG 314 >4P9S-A nrPDB Length = 848 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 54/274 (19%), Positives = 100/274 (36%), Gaps = 37/274 (13%) Query: 2 ETKDLIVIGGGINGAGIAADAAGRGLS-VLMLEAQDLACATSSASSKLI---HGGLRYLE 57 + + ++IGGG G +A A G+ V++LE +L ++ ++ L H G+ + Sbjct: 22 DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKK 81 Query: 58 -HYEFRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKRTS 116 HY+ + E L E E + H P RL P + ++ + + Sbjct: 82 IHYDSIKLYERL-EEETGQVVGFH--QPGSIRLATTPERVDEFKYQMTRTNWHATEQYII 138 Query: 117 LPGSTGLRFGANSVLKPEIKRGFEY--SDCWVDDARLVLANAQMVVRKGGEVLTRTRATS 174 P F +L + Y D +D L +A A + G + TS Sbjct: 139 EPEKIHELF---PLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGALLKYPAPVTS 195 Query: 175 AR-RENGLWIVEAEDIDTGKKYSWQARGLVNATGPWVKQFFDDGMHLPSPYGIRLIKGSH 233 + R +G W VE + S +A +VNA G W + G + + + ++ + Sbjct: 196 LKPRPDGTWDVET------PQGSVRANRIVNAAGFWA---REVGKMIGLDHPLIPVQHQY 246 Query: 234 IVVPRVH--------------TQKQAYILQNEDK 253 ++ + + Y+ Q D Sbjct: 247 VITSTIPEVKALKRELPVLRDLEGSYYLRQERDG 280 >2BS2-A nrPDB Length = 660 Score = 39.3 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 41/230 (17%), Positives = 84/230 (36%), Gaps = 30/230 (13%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLE------- 57 D +VIGGG+ G A +GLS ++L + + S+A+ + L + Sbjct: 7 DSLVIGGGLAGLRAAVATQQKGLSTIVLSLIPVKRSHSAAAQGGMQASLGNSKMSDGDNE 66 Query: 58 --HY-EFRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKR 114 H+ + S+ +++V +R RI H G R Sbjct: 67 DLHFMDTVKGSDWGCDQKVARMFVNTAPKAIREL-----AAWGVPWTRI------HKGDR 115 Query: 115 TSLPGSTGLRFGANS-----VLKPEIKRGFEYSDCWVDDAR---LVLANAQMVVRKGGEV 166 ++ + + + ++ C+ DA ++ A A ++ G + Sbjct: 116 MAIINAQKTTITEEDFRHGLIHSRDFGGTKKWRTCYTADATGHTMLFAVANECLKLGVSI 175 Query: 167 LTRTRATSARRENGLWI-VEAEDIDTGKKYSWQARGLVNATGPWVKQFFD 215 R A + ++G D+ TG ++ A+G + ATG + + + + Sbjct: 176 QDRKEAIALIHQDGKCYGAVVRDLVTGDIIAYVAKGTLIATGGYGRIYKN 225 >5XMJ-A nrPDB Length = 627 Score = 38.9 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 43/221 (19%), Positives = 76/221 (34%), Gaps = 26/221 (11%) Query: 4 KDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYEFRL 63 D++ IGG + G +A +A+ GL +ML + SSA+ GG++ Sbjct: 6 TDVLCIGGALAGERVAVEASMAGLKTIMLSLVPPRRSHSSAAQ----GGMQAALGNAIMG 61 Query: 64 VSEA----------LAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIRI-GLFMYDHLG 112 ++ ++ ++A A + H W + G Y G Sbjct: 62 DGDSPDVHFADTVKGSDWGCDQEVARIFADTAPIVMREVAHWGVPWNRVVPGKHTYYKGG 121 Query: 113 KRTSLPGSTGLRFGANSVLKPEIKRGFEYS--DCWVDD--ARLVLANAQ-MVVRKGGEVL 167 K + L G + C+ D R VL ++ G V Sbjct: 122 KPFEAEEK-----AEKAGLIHARAFGGTAAWRTCYTADGTGRSVLNTLDTKCLQYGVTVH 176 Query: 168 TRTRATSARRENGLWI-VEAEDIDTGKKYSWQARGLVNATG 207 R +A + + G + A + TG+ ++ A + ATG Sbjct: 177 DRMQAEALIHDGGNCLGCIARCLRTGELVAYLATSTLIATG 217 >1ZOV-A nrPDB Length = 386 Score = 38.2 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 45/233 (19%), Positives = 77/233 (33%), Gaps = 30/233 (12%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYEFRL- 63 D+IV+G G G A +G+ L++++ D ++ HG R + H Sbjct: 5 DVIVVGAGSMGMAAGYYLAKQGVKTLLVDSFD-----PPHTNGSHHGDTRIIRHAYGEGR 59 Query: 64 --VSEALAEREVLLKMAP---HIAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKRTSLP 118 V AL +E+ ++ H F L + P A++ H + Sbjct: 60 EYVPFALRAQELWYELEKETHHKIFTQTGVLVYGPKGGSAFVSETMEAANIHSLEHELFE 119 Query: 119 GST------GLRFGANSVLKPEIKRGFEYSDCWVDDARLVLANAQMVVRKGGEVLTRTRA 172 G G+ N E G +S+ + R ++ G VLT T Sbjct: 120 GKQLTDRWAGVEVPDNYEAIFEPNSGVLFSENCIQAYR------ELAEAHGATVLTYTPV 173 Query: 173 TSARRENGLWIVEAEDIDTGKKYSWQARGLVNATGPWVKQFFDD-GMHLPSPY 224 L ++ K S+ A LV + G W + + +P Sbjct: 174 EDFEVTEDLVTIKT------AKGSYTANKLVVSMGAWNSKLLSKLDVEIPLQP 220 >2UZZ-A nrPDB Length = 372 Score = 37.4 bits (85), Expect = 0.015, Method: Composition-based stats. Identities = 51/287 (17%), Positives = 92/287 (32%), Gaps = 51/287 (17%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLE--AQDLACATSSASSKLI-HGGLRYLEHYEF 61 DLI+IG G GA A GL+VLM + + ++LI H ++ Sbjct: 4 DLIIIGSGSVGAAAGYYATRAGLNVLMTDAHMPPHQHGSHHGDTRLIRHAYGEGEKYVPL 63 Query: 62 RLVSEALAE-------------REVLLKMAPHIAFPMRFRLPHRPHLRPAWMIRIGLFMY 108 L ++ L + R ++ + P L + H W + + Sbjct: 64 VLRAQMLWDELSRHNEDDPIFVRSGVINLGP----ADSTFLANVAHSAEQWQLNV----- 114 Query: 109 DHLGKRTSLPGSTGLRFGANSVLKPEIKRGFEYSDCWVDDARLVLANAQMVVRKGGEVLT 168 + L + + +R N + E GF S+ + Q+ G L Sbjct: 115 EKLDAQGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTW------IQLAKEAGCAQLF 168 Query: 169 RTRATSARRENGLWIVEAEDIDTGKKYSWQARGLVNATGPWVKQFFDDGMHLPSPYGIRL 228 T+ R ++ +E D +QA+ + G WVK + LP ++ Sbjct: 169 NCPVTAIRHDDDGVTIETAD------GEYQAKKAIVCAGTWVKDLLPE---LPVQPVRKV 219 Query: 229 -----IKGSHIVVPRVHTQKQAYILQN-EDKRIVFVIPWMDEFSIIG 269 G + V + + + P ++ IG Sbjct: 220 FAWYQADGRYSVKNKFPA-----FTGELPNGDQYYGFPAENDALKIG 261 >3SM8-A nrPDB Length = 381 Score = 37.0 bits (84), Expect = 0.019, Method: Composition-based stats. Identities = 62/337 (18%), Positives = 106/337 (31%), Gaps = 48/337 (14%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYEFRLV 64 D +VIG GI GA + G V++ ++ S+ H + Y ++ Sbjct: 11 DYLVIGAGIAGASTGYWLSAHGRVVVLEREAQPGYHSTGRSAA--HYTVAY---GTPQVR 65 Query: 65 SEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKRTSLPGSTGLR 124 + A R P F L RP + + + + +P L Sbjct: 66 ALTAASRAFFDN--PPAGFCEHPLLSPRPEMVVDFSDDPEELRRQYESGKALVPQMRLLD 123 Query: 125 FGAN----SVLKPEIKRGFEY--SDCWVDDARLVLANAQMVVRKGGEVLTRTRATSARRE 178 VL+ + G Y + +D L + + R G+VL A RR Sbjct: 124 AEQACSIVPVLRRDKVFGATYDPTGADIDTDALHQGYLRGIRRNQGQVLCNHEALEIRRV 183 Query: 179 NGLWIVEAEDIDTGKKYSWQARGLVNATGPWVKQFFDDGMHLPSPYGIRLIKGSHIVVPR 238 +G W V S++A LVNA G W P G++ + S + Sbjct: 184 DGAWEVRC------DAGSYRAAVLVNAAGAWCDAIAGLAGVRPL--GLQPKRRSAFIFAP 235 Query: 239 VH------------TQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYKGDPKAVKIEE 286 + Y+ D ++ P D D + +++ Sbjct: 236 PPGIDCHDWPMLVSLDESFYL--KPDAGMLLGSP--------ANADPVEAHDVQPEQLDI 285 Query: 287 SEINYLLNVYNTHFKKQLSRDDIVWTYSGVRPLCDDE 323 + YL+ T L+ T++G+R D Sbjct: 286 ATGMYLIEEATT-----LTIRRPEHTWAGLRSFVADG 317 >1QO8-A nrPDB Length = 566 Score = 36.6 bits (83), Expect = 0.026, Method: Composition-based stats. Identities = 11/46 (23%), Positives = 22/46 (47%) Query: 2 ETKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSK 47 ET ++V+G G G + A G +V++++ + S S+ Sbjct: 120 ETTQVLVVGAGSAGFNASLAAKKAGANVILVDKAPFSGGNSMISAG 165 >3ATQ-A nrPDB Length = 453 Score = 35.9 bits (81), Expect = 0.045, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 32/64 (50%), Gaps = 6/64 (9%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQ------DLACATSSASSKLIHGGLRYLEH 58 D+++IGGG G+ A + RGL +L+++++ D C + + + G+ Y + Sbjct: 8 DVLIIGGGFAGSSAAYQLSRRGLKILLVDSKPWNRIGDKPCGDAVSKAHFDKLGMPYPKG 67 Query: 59 YEFR 62 E Sbjct: 68 EELE 71 >6MEL-B nrPDB Length = 387 Score = 35.5 bits (80), Expect = 0.053, Method: Composition-based stats. Identities = 39/231 (16%), Positives = 79/231 (34%), Gaps = 44/231 (19%) Query: 155 NAQMVVRKGGEVLTRTRA---TSARRENGLWIVEAEDIDTGKKYSWQARGLVNATGPWVK 211 + + V ++ E + + + +GL + +D + + L++ K Sbjct: 132 DIEKVAKESPEKIAKVGIDPQIGFKMFHGLEVARVLGLDKDE-----GKKLISMIAKLYK 186 Query: 212 QFFDDGMH-LPSPYGIRLIKGSHIVVPRV----------HTQKQAYILQNEDKRIVFVIP 260 + D M+ L I+ +G + H + E+ P Sbjct: 187 LYMDKDMNMLEINPLIKTAEGDFYALDAKCSFDDSALYRHPEIAELRDTTEEN------P 240 Query: 261 WMDEFSIIGTTDVEYKGDPKAVKIEESEINYLLNVYNTHFKKQLSRDDIVWTYSGVRP-- 318 E + G + V+ GD + N + D I YSG +P Sbjct: 241 AEREAAEFGLSYVKLDGDVAC-------------MVNGAGLAMATMDII--NYSGAKPAN 285 Query: 319 -LCDDESDSPQAITRDYTLDIHDENGKAPLLSVFGGKLTTYRKLAEHALEK 368 L SP+ + + + + + D+N K +++FGG + ++A LE Sbjct: 286 FLDVGGGASPETVAKAFEIILRDKNVKVIFINIFGG-IVRCDRIANGILEA 335 >4K22-A nrPDB Length = 365 Score = 35.5 bits (80), Expect = 0.054, Method: Composition-based stats. Identities = 13/33 (39%), Positives = 21/33 (63%) Query: 1 METKDLIVIGGGINGAGIAADAAGRGLSVLMLE 33 M++ D+ ++GGG+ G +A G GL V +LE Sbjct: 1 MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLE 33 >2YVG-A nrPDB Length = 408 Score = 34.7 bits (78), Expect = 0.091, Method: Composition-based stats. Identities = 12/30 (40%), Positives = 20/30 (66%) Query: 6 LIVIGGGINGAGIAADAAGRGLSVLMLEAQ 35 L+++GGG+ G +AA A G+ V ++E Q Sbjct: 148 LLIVGGGVIGLELAATARTAGVHVSLVETQ 177 >2BXR-A nrPDB Length = 527 Score = 34.7 bits (78), Expect = 0.099, Method: Composition-based stats. Identities = 17/38 (44%), Positives = 24/38 (63%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATS 42 D++VIGGGI+G A G+SVL+LEA+D + Sbjct: 15 DVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRT 52 >4DGK-A nrPDB Length = 501 Score = 33.9 bits (76), Expect = 0.17, Method: Composition-based stats. Identities = 12/35 (34%), Positives = 17/35 (48%) Query: 8 VIGGGINGAGIAADAAGRGLSVLMLEAQDLACATS 42 VIG G G +A G+ VL+LE +D + Sbjct: 6 VIGAGFGGLALAIRLQAAGIPVLLLEQRDKPGGRA 40 >1KQY-A nrPDB Length = 273 Score = 33.5 bits (75), Expect = 0.23, Method: Composition-based stats. Identities = 20/93 (21%), Positives = 37/93 (39%), Gaps = 11/93 (11%) Query: 6 LIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSK----------LIHGGLRY 55 ++ +GGGI +A+ A + ++ + L +SS + HG Y Sbjct: 75 MLSLGGGIGSYTLASQADAKNVADYLWN-NFLGGKSSSRPLGDAVLDGIDFAIAHGSTLY 133 Query: 56 LEHYEFRLVSEALAEREVLLKMAPHIAFPMRFR 88 + L + + ++V L AP FP R+ Sbjct: 134 WDDLARYLSAYSKQGKKVYLTAAPQCPFPDRYL 166 >6CMZ-A nrPDB Length = 466 Score = 33.2 bits (74), Expect = 0.29, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 18/38 (47%) Query: 2 ETKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLAC 39 E L+VIGGG G A A G+ +++E L Sbjct: 7 EHTTLLVIGGGPGGYVAAIRAGQLGIPTVLVERDRLGG 44 >1NG3-A nrPDB Length = 390 Score = 32.8 bits (73), Expect = 0.34, Method: Composition-based stats. Identities = 46/308 (14%), Positives = 88/308 (28%), Gaps = 52/308 (16%) Query: 29 VLMLEAQDLACATSSASSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPHIAFPMRFR 88 + E+ + T+SA++ ++ ER+ A H + Sbjct: 51 TALFESGTMGGRTTSAAAGML-------------GAHAECEERDAFFDFAMHSQRLYKGL 97 Query: 89 LPH---------RPHLRPAWMIRIGLFMYDHLGKRTSLPGSTGLRFGANSVLKPE--IKR 137 R H + ++ D L R + + VL+ E Sbjct: 98 GEELYALSGVDIRQHNGGMF--KLAFSEEDVLQLRQMDDLDSVSWYSKEEVLEKEPYASG 155 Query: 138 GFEYSDCWVDDAR-----LVLANAQMVVRKGGEVLTRTRATSARRENGLWIVEAEDIDTG 192 + DD + A + G E+ T R+ ++ D Sbjct: 156 DIFGASFIQDDVHVEPYFVCKAYVKAAKMLGAEIFEHTPVLHVERDGEALFIKTPSGD-- 213 Query: 193 KKYSWQARGLVNATGPWVKQFFDDGMHLPSPYGIRLIKGSHIVV--PRVHTQKQAYILQN 250 A +V A+G W FF L +KG + V + K Y Sbjct: 214 ----VWANHVVVASGVWSGMFFK---QLGLNNAFLPVKGECLSVWNDDIPLTKTLYHDH- 265 Query: 251 EDKRIVFVIPWMDEFSIIGTTDVEYKGDPKAVKIEESEINYLLNVYNTHFKKQLSRDDIV 310 +++P ++G T GD + + ++ T + + Sbjct: 266 -----CYIVPRKSGRLVVGAT--MKPGDWSETP-DLGGLESVMKKAKTMLPP-IQNMKVD 316 Query: 311 WTYSGVRP 318 ++G+RP Sbjct: 317 RFWAGLRP 324 >3NK2-X nrPDB Length = 431 Score = 32.8 bits (73), Expect = 0.35, Method: Composition-based stats. Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 1/48 (2%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQD-LACATSSASSKLIHG 51 D IV+GGG +G A D G VL+LE + L S S+ + G Sbjct: 3 DAIVVGGGFSGLKAARDLTNAGKKVLLLEGGERLGGRAYSRESRNVPG 50 >2R9Z-A nrPDB Length = 463 Score = 32.8 bits (73), Expect = 0.37, Method: Composition-based stats. Identities = 15/35 (42%), Positives = 20/35 (57%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLAC 39 DLI IGGG G +A AA G V ++E++ L Sbjct: 6 DLIAIGGGSGGLAVAEKAAAFGKRVALIESKALGG 40 >6BRD-A nrPDB Length = 476 Score = 32.8 bits (73), Expect = 0.38, Method: Composition-based stats. Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 4/67 (5%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYEFRLV 64 D+IV+GGG G +A + G+ VL+LE + S + L +R +E R + Sbjct: 3 DVIVVGGGPTGLMLAGELRLHGVRVLVLEKETEPTRQS-RAQGL---HVRSIEVMAQRGL 58 Query: 65 SEALAER 71 E ER Sbjct: 59 LERFLER 65 >3URH-A nrPDB Length = 491 Score = 32.8 bits (73), Expect = 0.41, Method: Composition-based stats. Identities = 26/87 (29%), Positives = 34/87 (39%), Gaps = 7/87 (8%) Query: 1 METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACAT-----SSASSKLIHGGLRY 55 M DLIVIG G G A AA G+ V ++E + T S L+H + Sbjct: 23 MMAYDLIVIGSGPGGYVCAIKAAQLGMKVAVVEKRSTYGGTCLNVGCIPSKALLHASEMF 82 Query: 56 --LEHYEFRLVSEALAEREVLLKMAPH 80 +H L E + L KM H Sbjct: 83 HQAQHGLEALGVEVANPKLNLQKMMAH 109 >2IVE-A nrPDB Length = 478 Score = 32.4 bits (72), Expect = 0.42, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 19/36 (52%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACA 40 ++ V+GGGI+G +A RG ++LE+ Sbjct: 18 NVAVVGGGISGLAVAHHLRSRGTDAVLLESSARLGG 53 >4ZN0-A nrPDB Length = 311 Score = 32.4 bits (72), Expect = 0.45, Method: Composition-based stats. Identities = 16/40 (40%), Positives = 21/40 (52%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSA 44 DLI+IGGG G A GL L+LE +++ S A Sbjct: 9 DLIIIGGGPAGLTAGIYAVRYGLDTLILERNEISGQISMA 48 >4EIQ-A nrPDB Length = 549 Score = 32.4 bits (72), Expect = 0.47, Method: Composition-based stats. Identities = 49/236 (20%), Positives = 81/236 (34%), Gaps = 37/236 (15%) Query: 4 KDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYEFRL 63 D++++GGG G +A D A R + L+++A D T S + G R +E + Sbjct: 27 TDVLILGGGPVGMALALDLAHRQVGHLVVDAGD-GTITHPKVSTI---GPRSMELFR--- 79 Query: 64 VSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKRTSLPGSTGL 123 +A I P L AW+ R+G H R L G+ Sbjct: 80 ----------RWGVAKQIRTAGW---PGDHPLDAAWVTRVG----GHEVYRIPL-GTADT 121 Query: 124 RFGANSVLKPEIKRGFEYSDCWVDDARLVLANAQMVVRKGGEVLTRTRATSARRENGLWI 183 R +P+ + A + V G + TR+R S + + Sbjct: 122 RATPEHTPEPDA----------ICPAHWLAPLLAEAV--GERLRTRSRLDSFEQRDDHVR 169 Query: 184 VEAEDIDTGKKYSWQARGLVNATGPWVKQFFDDGMHLPSPYGIRLIKGSHIVVPRV 239 D+ TG + AR LV G G+ P + ++ + P + Sbjct: 170 ATITDLRTGATRAVHARYLVACDGASSPTRKALGIDAPPRHRTQVFRNILFRAPEL 225 >5KOX-A nrPDB Length = 476 Score = 32.4 bits (72), Expect = 0.49, Method: Composition-based stats. Identities = 13/44 (29%), Positives = 21/44 (47%), Gaps = 1/44 (2%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKL 48 D+I+ GGG G +A + G+ ++LE + S S L Sbjct: 6 DVIIAGGGPTGLMLAGELRLHGVRTVVLEKEP-TPNQHSRSRGL 48 >5A3F-A nrPDB Length = 754 Score = 32.4 bits (72), Expect = 0.49, Method: Composition-based stats. Identities = 34/147 (23%), Positives = 62/147 (42%), Gaps = 24/147 (16%) Query: 356 TTYRKLAEHALEKLTPYYQGIGPAWTKESVLPGGAIEGDRDDYAARLRRRYPFLTESLAR 415 T R + E+ L L Y G+ K+ I+G +D AA L R FL+ R Sbjct: 214 TDARDVLENKLLPLRRGYVGVVNRSQKD-------IDGKKDIKAAMLAERKFFLSHPAYR 266 Query: 416 HYARTYGS-NSELLLG--NAGTVSDLGEDFGHEFYEAELKYLVDHEWVR----RADDALW 468 H A G+ + + +L + D +F ++ + +L ++HE + +D Sbjct: 267 HIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKL-QGQL-LSIEHEVEAYKNFKPEDP-T 323 Query: 469 RRTKQGMWLNADQQSRVSQWLVEYTQQ 495 R+TK + V Q+ V++ ++ Sbjct: 324 RKTKALL-------QMVQQFAVDFEKR 343 >2EQ6-A nrPDB Length = 464 Score = 32.0 bits (71), Expect = 0.56, Method: Composition-based stats. Identities = 19/39 (48%), Positives = 23/39 (58%) Query: 1 METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLAC 39 M+T DLIVIG G G A AA GL VL +EA ++ Sbjct: 4 MKTYDLIVIGTGPGGYHAAIRAAQLGLKVLAVEAGEVGG 42 >1PS9-A nrPDB Length = 671 Score = 32.0 bits (71), Expect = 0.59, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 20/41 (48%) Query: 1 METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACAT 41 ++ K+L V+G G G A +AA RG V + +A Sbjct: 371 VQKKNLAVVGAGPAGLAFAINAAARGHQVTLFDAHSEIGGQ 411 >2YQU-A nrPDB Length = 455 Score = 32.0 bits (71), Expect = 0.65, Method: Composition-based stats. Identities = 14/40 (35%), Positives = 19/40 (47%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSA 44 DL+VIG G G A AA G+ V ++E + T Sbjct: 3 DLLVIGAGPGGYVAAIRAAQLGMKVGVVEKEKALGGTCLR 42 >4EMJ-A nrPDB Length = 410 Score = 32.0 bits (71), Expect = 0.65, Method: Composition-based stats. Identities = 15/34 (44%), Positives = 21/34 (61%) Query: 3 TKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQD 36 L+++GGG+ G +A A GLSV +LEA D Sbjct: 143 ATRLLIVGGGLIGCEVATTARKLGLSVTILEAGD 176 >1O5W-A nrPDB Length = 534 Score = 32.0 bits (71), Expect = 0.69, Method: Composition-based stats. Identities = 15/38 (39%), Positives = 24/38 (63%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATS 42 D++VIGGGI+G A + ++VL+LEA+D + Sbjct: 23 DVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRT 60 >3ABT-A nrPDB Length = 662 Score = 31.6 bits (70), Expect = 0.77, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 21/39 (53%) Query: 2 ETKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACA 40 +T +I+IG G++G A G+ V +LEA+D Sbjct: 106 KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 144 >6N7F-A nrPDB Length = 453 Score = 31.2 bits (69), Expect = 1.00, Method: Composition-based stats. Identities = 15/35 (42%), Positives = 19/35 (54%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLAC 39 D IVIGGG G A AA G VL+ E +++ Sbjct: 9 DYIVIGGGSAGIASANRAAMHGAKVLLAEGKEIGG 43 >5L3D-A nrPDB Length = 852 Score = 31.2 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 21/39 (53%) Query: 2 ETKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACA 40 +T +I+IG G++G A G+ V +LEA+D Sbjct: 277 KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 >3KVE-A nrPDB Length = 486 Score = 31.2 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 14/37 (37%), Positives = 21/37 (56%) Query: 4 KDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACA 40 K ++V+G G++G A AG G V +LEA + A Sbjct: 34 KHVVVVGAGMSGLSAAYVLAGAGHKVTVLEASERAGG 70 >3R9U-A nrPDB Length = 315 Score = 30.9 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 11/44 (25%), Positives = 22/44 (50%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKL 48 D+ +IGGG G A GL +++ + + ++SS++ Sbjct: 6 DVAIIGGGPAGLSAGLYATRGGLKNVVMFEKGMPGGQITSSSEI 49 >1SEZ-A nrPDB Length = 504 Score = 30.5 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 10/101 (9%) Query: 3 TKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACAT--SSASSKLI-HGGLRYL--E 57 K + VIG G++G A GL+V + EA+ A S + LI G + Sbjct: 13 AKRVAVIGAGVSGLAAAYKLKIHGLNVTVFEAEGKAGGKLRSVSQDGLIWDEGANTMTES 72 Query: 58 HYEFRLVSEALAEREV----LLKMAPHIAFP-MRFRLPHRP 93 + + ++L RE L + +IA LP P Sbjct: 73 EGDVTFLIDSLGLREKQQFPLSQNKRYIARNGTPVLLPSNP 113 >1V59-A nrPDB Length = 478 Score = 30.5 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 20/40 (50%) Query: 2 ETKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACAT 41 ++ D+++IGGG G A AA G + +E + T Sbjct: 4 KSHDVVIIGGGPAGYVAAIKAAQLGFNTACVEKRGKLGGT 43 >3L8K-A nrPDB Length = 466 Score = 30.5 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 19/35 (54%) Query: 4 KDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLA 38 +D+++IG G G IA+ G+ ++E D A Sbjct: 173 QDMVIIGAGYIGLEIASIFRLMGVQTHIIEMLDRA 207 >2JB2-A nrPDB Length = 489 Score = 30.5 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 11/38 (28%), Positives = 18/38 (47%) Query: 3 TKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACA 40 + ++V+GGG G A + G V +LEA+ Sbjct: 11 SHSVVVLGGGPAGLCSAFELQKAGYKVTVLEARTRPGG 48 >4EHJ-A nrPDB Length = 392 Score = 30.5 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 25/128 (19%), Positives = 53/128 (41%), Gaps = 18/128 (14%) Query: 1 METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHG-------GL 53 ++ +++++GGGI I A G + + E +A AT + G + Sbjct: 205 LDKVEILIVGGGIANTFI--KAEGFDVGNSLYEQDLVAEATEILAKAKALGVNIPVPVDV 262 Query: 54 RYLEHYE------FRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIRIGLFM 107 R + + + VS+ +A+ E++L + P + L + W +G+F Sbjct: 263 RVAKEFSENAQAIIKKVSDVVAD-EMILDIGPESQKIIAELLKSANTI--LWNGPVGVFE 319 Query: 108 YDHLGKRT 115 +D+ + T Sbjct: 320 FDNFAEGT 327 >1EVY-A nrPDB Length = 366 Score = 30.5 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 22/38 (57%), Gaps = 1/38 (2%) Query: 4 KDLIVIGGGI-NGAGIAADAAGRGLSVLMLEAQDLACA 40 K+++ IG G+ NG G+ +A + +LE +DL A Sbjct: 210 KNVLAIGSGVANGLGMGLNARAALIMRGLLEIRDLTAA 247 >1REO-A nrPDB Length = 486 Score = 30.5 bits (67), Expect = 2.0, Method: Composition-based stats. Identities = 13/37 (35%), Positives = 21/37 (56%) Query: 4 KDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACA 40 K ++V+G G++G A +G G V +LEA + A Sbjct: 34 KHVVVVGAGMSGLSAAYVLSGAGHQVTVLEASERAGG 70 >3L43-A nrPDB Length = 319 Score = 30.5 bits (67), Expect = 2.0, Method: Composition-based stats. Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 7/68 (10%) Query: 356 TTYRKLAEHALEKLTPYYQGIGPAWTKESVLPGGAIEGDRDDYAARLRRRYPFLTESLAR 415 T R + E+ L L Y G+ K+ I+G +D AA L R FL+ R Sbjct: 227 TDARDVLENKLLPLRRGYVGVVNRSQKD-------IDGKKDIKAAMLAERKFFLSHPAYR 279 Query: 416 HYARTYGS 423 H A G+ Sbjct: 280 HIADRMGT 287 >2NVK-X nrPDB Length = 488 Score = 30.5 bits (67), Expect = 2.0, Method: Composition-based stats. Identities = 27/93 (29%), Positives = 35/93 (37%), Gaps = 12/93 (12%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGL--------RYL 56 DLIVIGGG G A +A G V L D T + +K GG + L Sbjct: 11 DLIVIGGGSAGLACAKEAVLNGARVACL---DFVKPTPTLGTKWGVGGTCVNVGCIPKKL 67 Query: 57 EHYEFRLVSEALAEREVLLKMAPHIAFPMRFRL 89 H + L+ EA+ E P +L Sbjct: 68 MH-QASLLGEAVHEAAAYGWNVDDKIKPDWHKL 99 >1F14-A nrPDB Length = 310 Score = 30.5 bits (67), Expect = 2.0, Method: Composition-based stats. Identities = 21/51 (41%), Positives = 28/51 (54%), Gaps = 3/51 (5%) Query: 4 KDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLR 54 K + VIGGG+ GAGIA AA G +V+++ D + S K I LR Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATGHTVVLV---DQTEDILAKSKKGIEESLR 63 >3HDH-A nrPDB Length = 302 Score = 30.1 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 21/51 (41%), Positives = 28/51 (54%), Gaps = 3/51 (5%) Query: 4 KDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLR 54 K + VIGGG+ GAGIA AA G +V+++ D + S K I LR Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATGHTVVLV---DQTEDILAKSKKGIEESLR 63 >4C3X-A nrPDB Length = 530 Score = 30.1 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 15/41 (36%), Positives = 23/41 (56%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSAS 45 D++V+G G A AA +GL+ ++LE D TS+ S Sbjct: 29 DVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYS 69 >1NEP-A nrPDB Length = 130 Score = 30.1 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 13/92 (14%), Positives = 31/92 (33%), Gaps = 3/92 (3%) Query: 49 IHGGLRYLEHYEFRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIRIGLF-M 107 +H G Y + F +++ + + V+ + I P +P + I Sbjct: 30 LHRGQSYSVNVTFTSNTQSQSSKAVVHGIVMGIPVPFP--IPESDGCKSGIRCPIEKDKT 87 Query: 108 YDHLGKRTSLPGSTGLRFGANSVLKPEIKRGF 139 Y+++ K ++ L + + F Sbjct: 88 YNYVNKLPVKNEYPSIKVVVEWELTDDKNQRF 119 >3ICS-A nrPDB Length = 588 Score = 30.1 bits (66), Expect = 2.4, Method: Composition-based stats. Identities = 10/29 (34%), Positives = 16/29 (55%) Query: 8 VIGGGINGAGIAADAAGRGLSVLMLEAQD 36 VIGGG G + + RG+ V ++E + Sbjct: 192 VIGGGFIGVEMVENLRERGIEVTLVEMAN 220 >5G3Y-A nrPDB Length = 226 Score = 30.1 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 29/71 (40%), Gaps = 6/71 (8%) Query: 69 AEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKRTSLPGSTGLRFGAN 128 AE+ V PHI+ FR + +GL +++ K +P + Sbjct: 17 AEKIVEEYGIPHISTGDMFRAAIKEGT------ELGLKAKEYMDKGELVPDEVTIGLVKE 70 Query: 129 SVLKPEIKRGF 139 + +P+ K+GF Sbjct: 71 RLSQPDCKKGF 81 >2BHU-A nrPDB Length = 602 Score = 29.7 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 21/86 (24%), Positives = 28/86 (32%), Gaps = 8/86 (9%) Query: 111 LGKRTSLPGSTGLRFGANSVLKPEIKRGFEYSDCWVDD----ARLVLANAQMVV----RK 162 L + G T L + P++ W DD R+ L Q R Sbjct: 292 LAQEIHELGGTHLLLAEDHRNLPDLVTVNHLDGIWTDDFHHETRVTLTGEQEGYYAGYRG 351 Query: 163 GGEVLTRTRATSARRENGLWIVEAED 188 G E L T R E W V+ E+ Sbjct: 352 GAEALAYTIRRGWRYEGQFWAVKGEE 377 >2CVJ-A nrPDB Length = 180 Score = 29.7 bits (65), Expect = 3.1, Method: Composition-based stats. Identities = 14/29 (48%), Positives = 19/29 (65%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLE 33 D+IV+GGG +G A A GL VL+L+ Sbjct: 3 DVIVVGGGPSGLSAALFLARAGLKVLVLD 31 >6DLV-b nrPDB Length = 748 Score = 29.7 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 34/145 (23%), Positives = 56/145 (38%), Gaps = 20/145 (13%) Query: 356 TTYRKLAEHALEKLTPYYQGIGPAWTKESVLPGGAIEGDRDDYAARLRRRYPFLTESLAR 415 T R + E+ L L Y G+ K+ I+G +D AA R FL+ R Sbjct: 214 TDARDVLENKLLPLRRGYIGVVNRSQKD-------IDGKKDITAALAAERKFFLSHPSYR 266 Query: 416 HYARTYGSN-SELLLGNAGTVSDLGEDFGH-EFYEAEL---KYLVDHEWVRRADDALWRR 470 H A G+ + +L T G +++L + V+ R DD R+ Sbjct: 267 HLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKLQSQLLSIEKEVEEYKNFRPDDP-ARK 325 Query: 471 TKQGMWLNADQQSRVSQWLVEYTQQ 495 TK + V Q+ V++ ++ Sbjct: 326 TKALL-------QMVQQFAVDFEKR 343 >1F8S-A nrPDB Length = 498 Score = 29.7 bits (65), Expect = 3.5, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 19/37 (51%) Query: 4 KDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACA 40 K ++++G G+ G A AG G V +LEA + Sbjct: 34 KHVVIVGAGMAGLSAAYVLAGAGHQVTVLEASERPGG 70 >4UUD-B nrPDB Length = 864 Score = 29.7 bits (65), Expect = 3.5, Method: Composition-based stats. Identities = 34/145 (23%), Positives = 56/145 (38%), Gaps = 20/145 (13%) Query: 356 TTYRKLAEHALEKLTPYYQGIGPAWTKESVLPGGAIEGDRDDYAARLRRRYPFLTESLAR 415 T R + E+ L L Y G+ K+ I+G +D AA R FL+ R Sbjct: 214 TDARDVLENKLLPLRRGYIGVVNRSQKD-------IDGKKDITAALAAERKFFLSHPSYR 266 Query: 416 HYARTYGSN-SELLLGNAGTVSDLGEDFGH-EFYEAEL---KYLVDHEWVRRADDALWRR 470 H A G+ + +L T G +++L + V+ R DD R+ Sbjct: 267 HLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKLQSQLLSIEKEVEEYKNFRPDDP-ARK 325 Query: 471 TKQGMWLNADQQSRVSQWLVEYTQQ 495 TK + V Q+ V++ ++ Sbjct: 326 TKALL-------QMVQQFAVDFEKR 343 >3IHG-A nrPDB Length = 535 Score = 29.3 bits (64), Expect = 4.1, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 19/29 (65%) Query: 5 DLIVIGGGINGAGIAADAAGRGLSVLMLE 33 D++V+G G+ G A A +G+ VL++E Sbjct: 7 DVLVVGAGLGGLSTAMFLARQGVRVLVVE 35 >4AP1-A nrPDB Length = 549 Score = 29.3 bits (64), Expect = 4.4, Method: Composition-based stats. Identities = 11/38 (28%), Positives = 17/38 (44%) Query: 3 TKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACA 40 + D++V+G GI G +GL+V EA Sbjct: 21 SYDVVVVGAGIAGLYAIHRFRSQGLTVRAFEAASGVGG 58 >5MOG-A nrPDB Length = 497 Score = 29.3 bits (64), Expect = 4.4, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 18/35 (51%) Query: 6 LIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACA 40 +++ G G+ G A A G ++LEA+D+ Sbjct: 20 VVIAGAGLAGLSTAKYLADAGHKPILLEARDVLGG 54 >3NIX-A nrPDB Length = 421 Score = 29.3 bits (64), Expect = 4.6, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 17/36 (47%) Query: 2 ETKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDL 37 E D++VIG G G A+ G V ++E Q Sbjct: 4 EKVDVLVIGAGPAGTVAASLVNKSGFKVKIVEKQKF 39 >1D4E-A nrPDB Length = 572 Score = 28.9 bits (63), Expect = 5.1, Method: Composition-based stats. Identities = 50/238 (21%), Positives = 90/238 (37%), Gaps = 31/238 (13%) Query: 2 ETKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHY-E 60 ET D+++IG G G A A G V++LE + + ++KL GG+ E + Sbjct: 125 ETTDVVIIGSGGAGLAAAVSARDAGAKVILLEKEPIPGG----NTKLAAGGMNAAETKPQ 180 Query: 61 FRLVSEALAEREV--LLKMAPHIAFPMRF-RLPHRPHLRPAWMIRIGLFMYDHLGKRTSL 117 +L E + + +K +I P L + W+ +G M D Sbjct: 181 AKLGIEDKKQIMIDDTMKGGRNINDPELVKVLANNSSDSIDWLTSMGADMTD-------- 232 Query: 118 PGSTGLRFGANSVLKPEIKRGFEYSDCWVDDARLVLANAQMVVRKGGEVLTRTRATSARR 177 R G SV + G V A+++ N V++G ++ +R Sbjct: 233 ----VGRMGGASVNRSHRPTGGAGVGAHV--AQVLWDN---AVKRGTDIRLNSRVVRILE 283 Query: 178 E-NGLWI-VEAEDIDTGKKYSWQARGLVNATGPWVKQFFDDGMHLPSPYGIRLIKGSH 233 + +G V + TG Y +A +V A G + K ++ ++ K ++ Sbjct: 284 DASGKVTGVLVKGEYTG-YYVIKADAVVIAAGGFAK---NNERVSKYDPKLKGFKATN 337 >2A87-A nrPDB Length = 335 Score = 28.9 bits (63), Expect = 5.5, Method: Composition-based stats. Identities = 14/37 (37%), Positives = 18/37 (48%) Query: 4 KDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACA 40 +D+IVIG G G A AA L+ L+ E A Sbjct: 15 RDVIVIGSGPAGYTAALYAARAQLAPLVFEGTSFGGA 51 >2AKA-B nrPDB Length = 299 Score = 28.9 bits (63), Expect = 5.7, Method: Composition-based stats. Identities = 20/68 (29%), Positives = 28/68 (41%), Gaps = 7/68 (10%) Query: 356 TTYRKLAEHALEKLTPYYQGIGPAWTKESVLPGGAIEGDRDDYAARLRRRYPFLTESLAR 415 T R + E+ L L Y G+ K+ I+G +D AA R FL+ R Sbjct: 209 TDARDVLENKLLPLRRGYIGVVNRSQKD-------IDGKKDITAALAAERKFFLSHPSYR 261 Query: 416 HYARTYGS 423 H A G+ Sbjct: 262 HLADRMGT 269 >5F13-A nrPDB Length = 471 Score = 28.9 bits (63), Expect = 5.8, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 21/63 (33%), Gaps = 6/63 (9%) Query: 80 HIAFPMRFRLPHRPHLRPAWMIR-----IGLFMYDHLGKRTSLPGSTGLRFGANSVLKPE 134 H+ P RF + + I D L K S G +F V+K E Sbjct: 1 HMTIPGRFMTIDK-GTFGEYTASTRWPIIIQNAIDDLSKHQETEKSNGTKFEQGEVIKKE 59 Query: 135 IKR 137 +K Sbjct: 60 LKE 62 >2X2E-A nrPDB Length = 353 Score = 28.5 bits (62), Expect = 6.4, Method: Composition-based stats. Identities = 20/68 (29%), Positives = 28/68 (41%), Gaps = 7/68 (10%) Query: 356 TTYRKLAEHALEKLTPYYQGIGPAWTKESVLPGGAIEGDRDDYAARLRRRYPFLTESLAR 415 T R + E+ L L Y G+ K+ I+G +D AA R FL+ R Sbjct: 214 TDARDVLENKLLPLRRGYIGVVNRSQKD-------IDGKKDITAALAAERKFFLSHPSYR 266 Query: 416 HYARTYGS 423 H A G+ Sbjct: 267 HLADRMGT 274 >4OVI-A nrPDB Length = 542 Score = 28.2 bits (61), Expect = 8.1, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 16/39 (41%) Query: 2 ETKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACA 40 E D++V+G G +G G SV ++E Sbjct: 15 EEVDVLVVGAGFSGLYALYRLRELGRSVHVIETAGDVGG 53 >5TWC-A nrPDB Length = 344 Score = 28.2 bits (61), Expect = 8.3, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 20/37 (54%) Query: 4 KDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACA 40 KD+ +IGGG +G + A R +SV +++ Q Sbjct: 2 KDVTIIGGGPSGLYASFYAGLRDMSVRLIDVQSELGG 38 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.130 0.325 Lambda K H 0.267 0.0393 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,753,978 Number of Sequences: 36641 Number of extensions: 689142 Number of successful extensions: 2334 Number of sequences better than 10.0: 100 Number of HSP's better than 10.0 without gapping: 126 Number of HSP's successfully gapped in prelim test: 43 Number of HSP's that attempted gapping in prelim test: 2132 Number of HSP's gapped (non-prelim): 192 length of query: 501 length of database: 10,336,785 effective HSP length: 101 effective length of query: 400 effective length of database: 6,636,044 effective search space: 2654417600 effective search space used: 2654417600 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 61 (28.2 bits)