BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P12904 (322 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3TE5-C nrPDB 651 0.0 2OOY-G nrPDB 330 3e-91 6B2E-C nrPDB 191 4e-49 2UV7-A nrPDB 100 8e-22 4FXS-A nrPDB 37 0.015 1VRD-A nrPDB 31 0.61 2CU0-A nrPDB 30 1.3 1ZFJ-A nrPDB 30 1.4 4HG0-A nrPDB 29 2.1 5MIA-A nrPDB 29 2.8 3TSB-A nrPDB 29 2.9 6GIQ-f nrPDB 29 3.0 6HU9-f nrPDB 29 3.1 2RGH-A nrPDB 28 3.8 2RGO-A nrPDB 28 4.0 2YVX-A nrPDB 28 5.3 2YVZ-A nrPDB 28 6.0 >3TE5-C nrPDB Length = 323 Score = 651 bits (1679), Expect = 0.0, Method: Compositional matrix adjust. Identities = 321/321 (100%), Positives = 321/321 (100%) Query: 2 KPTQDSQEKVSIEQQLAVESIRKFLNSKTSYDVLPVSYRLIVLDTSLLVKKSLNVLLQNS 61 KPTQDSQEKVSIEQQLAVESIRKFLNSKTSYDVLPVSYRLIVLDTSLLVKKSLNVLLQNS Sbjct: 3 KPTQDSQEKVSIEQQLAVESIRKFLNSKTSYDVLPVSYRLIVLDTSLLVKKSLNVLLQNS 62 Query: 62 IVSAPLWDSKTSRFAGLLTTTDFINVIQYYFSNPDKFELVDKLQLDGLKDIERALGVDQL 121 IVSAPLWDSKTSRFAGLLTTTDFINVIQYYFSNPDKFELVDKLQLDGLKDIERALGVDQL Sbjct: 63 IVSAPLWDSKTSRFAGLLTTTDFINVIQYYFSNPDKFELVDKLQLDGLKDIERALGVDQL 122 Query: 122 DTASIHPSRPLFEACLKMLESRSGRIPLIDQDEETHREIVVSVLTQYRILKFVALNCRET 181 DTASIHPSRPLFEACLKMLESRSGRIPLIDQDEETHREIVVSVLTQYRILKFVALNCRET Sbjct: 123 DTASIHPSRPLFEACLKMLESRSGRIPLIDQDEETHREIVVSVLTQYRILKFVALNCRET 182 Query: 182 HFLKIPIGDLNIITQDNMKSCQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDV 241 HFLKIPIGDLNIITQDNMKSCQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDV Sbjct: 183 HFLKIPIGDLNIITQDNMKSCQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDV 242 Query: 242 LGLIKGGIYNDLSLSVGEALMRRSDDFEGVYTCTKNDKLSTIMDNIRKARVHRFFVVDDV 301 LGLIKGGIYNDLSLSVGEALMRRSDDFEGVYTCTKNDKLSTIMDNIRKARVHRFFVVDDV Sbjct: 243 LGLIKGGIYNDLSLSVGEALMRRSDDFEGVYTCTKNDKLSTIMDNIRKARVHRFFVVDDV 302 Query: 302 GRLVGVLTLSDILKYILLGSN 322 GRLVGVLTLSDILKYILLGSN Sbjct: 303 GRLVGVLTLSDILKYILLGSN 323 >2OOY-G nrPDB Length = 333 Score = 330 bits (847), Expect = 3e-91, Method: Compositional matrix adjust. Identities = 158/307 (51%), Positives = 225/307 (73%), Gaps = 3/307 (0%) Query: 15 QQLAVESIRKFLNSKTSYDVLPVSYRLIVLDTSLLVKKSLNVLLQNSIVSAPLWDSKTSR 74 Q+ A++ I+ F+ S+TSYDVLP S+RLIV D +L VK SL++L N+IVSAPLWDS+ ++ Sbjct: 7 QKGALKEIQAFIRSRTSYDVLPTSFRLIVFDVTLFVKTSLSLLTLNNIVSAPLWDSEANK 66 Query: 75 FAGLLTTTDFINVIQYYF---SNPDKFELVDKLQLDGLKDIERALGVDQLDTASIHPSRP 131 FAGLLT DF+NVI+YY+ S P+ +DK +L GL+++ER +G +T +HP Sbjct: 67 FAGLLTMADFVNVIKYYYQSSSFPEAIAEIDKFRLLGLREVERKIGAIPPETIYVHPMHS 126 Query: 132 LFEACLKMLESRSGRIPLIDQDEETHREIVVSVLTQYRILKFVALNCRETHFLKIPIGDL 191 L +ACL M +SR+ RIPLID D ET E++VSVLTQYRILKF+++NC+ET L++P+ + Sbjct: 127 LMDACLAMSKSRARRIPLIDVDGETGSEMIVSVLTQYRILKFISMNCKETAMLRVPLNQM 186 Query: 192 NIITQDNMKSCQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDVLGLIKGGIYN 251 I T N+ + M T V DVI+ML + +S+VPI++ G L+NVYE+ DV+ LI+ G Y+ Sbjct: 187 TIGTWSNLATASMETKVYDVIKMLAEKNISAVPIVNSEGTLLNVYESVDVMHLIQDGDYS 246 Query: 252 DLSLSVGEALMRRSDDFEGVYTCTKNDKLSTIMDNIRKARVHRFFVVDDVGRLVGVLTLS 311 +L LSVGEAL++R +F+GV+TC D+L I D I+ +RVHR FVVD+ +L G+L+L+ Sbjct: 247 NLDLSVGEALLKRPANFDGVHTCRATDRLDGIFDAIKHSRVHRLFVVDENLKLEGILSLA 306 Query: 312 DILKYIL 318 DIL YI+ Sbjct: 307 DILNYII 313 >6B2E-C nrPDB Length = 336 Score = 191 bits (485), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 113/302 (37%), Positives = 175/302 (57%), Gaps = 16/302 (5%) Query: 25 FLNSKTSYDVLPVSYRLIVLDTSLLVKKSLNVLLQNSIVSAPLWDSKTSRFAGLLTTTDF 84 F+ S YD++P S +L+V DTSL VKK+ L+ N + +APLWDSK F G+LT TDF Sbjct: 37 FMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDF 96 Query: 85 INVIQYYFSNPDKFELVDKLQLDGLKDIERALGVDQLDT----ASIHPSRPLFEACLKML 140 IN++ Y+ K LV +L+ K IE V D+ I P+ LF+A ++ Sbjct: 97 INILHRYY----KSALVQIYELEEHK-IETWREVYLQDSFKPLVCISPNASLFDAVSSLI 151 Query: 141 ESRSGRIPLIDQDEETHREIVVSVLTQYRILKFVALNCRE---THFLKIPIGDLNIITQD 197 ++ R+P+ID + + +LT RILKF+ L E F+ + +L I T Sbjct: 152 RNKIHRLPVIDPESGN----TLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYA 207 Query: 198 NMKSCQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDVLGLIKGGIYNDLSLSV 257 N+ + TTPV + + Q RVS++P++DE G ++++Y +DV+ L YN+L +SV Sbjct: 208 NIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSV 267 Query: 258 GEALMRRSDDFEGVYTCTKNDKLSTIMDNIRKARVHRFFVVDDVGRLVGVLTLSDILKYI 317 +AL RS FEGV C ++ L TI++ + +A VHR VVD+ + G+++LSDIL+ + Sbjct: 268 TKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQAL 327 Query: 318 LL 319 +L Sbjct: 328 VL 329 >2UV7-A nrPDB Length = 152 Score = 100 bits (249), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 51/137 (37%), Positives = 85/137 (62%) Query: 183 FLKIPIGDLNIITQDNMKSCQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDVL 242 F+ + +L I T N+ + TTPV + + Q RVS++P++DE G ++++Y +DV+ Sbjct: 15 FMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVI 74 Query: 243 GLIKGGIYNDLSLSVGEALMRRSDDFEGVYTCTKNDKLSTIMDNIRKARVHRFFVVDDVG 302 L YN+L +SV +AL RS FEGV C ++ L TI++ + +A VH VVD+ Sbjct: 75 NLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHGLVVVDEND 134 Query: 303 RLVGVLTLSDILKYILL 319 + G+++LSDIL+ ++L Sbjct: 135 VVKGIVSLSDILQALVL 151 >4FXS-A nrPDB Length = 496 Score = 36.6 bits (83), Expect = 0.015, Method: Compositional matrix adjust. Identities = 37/174 (21%), Positives = 75/174 (43%), Gaps = 17/174 (9%) Query: 147 IPLIDQDEETHREIVVSV-LTQYRILKFVALNC----RETHFLKIPIGDLNIITQDNMKS 201 IP++ +T E +++ L Q + F+ N + ++ I + ++T Sbjct: 44 IPMVSASMDTVTEARLAIALAQEGGIGFIHKNMSIEQQAAQVHQVKIFEAGVVTHPVTVR 103 Query: 202 CQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDVLGLIKGGIYNDLSLSVGEAL 261 + T + DV+++ + P++ EN L+ + DV DL+ SV + Sbjct: 104 PEQT--IADVMELTHYHGFAGFPVVTENNELVGIITGRDVR------FVTDLTKSVAAVM 155 Query: 262 MRRSDDFEGVYTCTKNDKLSTIMDNIRKARVHRFFVVDDVGRLVGVLTLSDILK 315 + E + T + + + + + KARV + VV+D +L G++T D K Sbjct: 156 TPK----ERLATVKEGATGAEVQEKMHKARVEKILVVNDEFQLKGMITAKDFHK 205 >1VRD-A nrPDB Length = 494 Score = 31.2 bits (69), Expect = 0.61, Method: Compositional matrix adjust. Identities = 23/110 (20%), Positives = 51/110 (46%), Gaps = 10/110 (9%) Query: 208 VIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDVLGLIKGGIYNDLSLSVGEALMRRSDD 267 V + I ++ + ++ +P++DE G L+ + DV +LS + + + R Sbjct: 114 VKEAIDLMAEYKIGGLPVVDEEGRLVGLLTNRDVR------FEKNLSKKIKDLMTPR--- 164 Query: 268 FEGVYTCTKNDKLSTIMDNIRKARVHRFFVVDDVGRLVGVLTLSDILKYI 317 E + + L + + + R+ + +V +LVG++T+ DI+ I Sbjct: 165 -EKLIVAPPDISLEKAKEILHQHRIEKLPLVSKDNKLVGLITIKDIMSVI 213 >2CU0-A nrPDB Length = 486 Score = 30.0 bits (66), Expect = 1.3, Method: Compositional matrix adjust. Identities = 12/24 (50%), Positives = 20/24 (83%) Query: 291 RVHRFFVVDDVGRLVGVLTLSDIL 314 R+ R VVD+ G+LVG++T+SD++ Sbjct: 180 RIDRLPVVDERGKLVGLITMSDLV 203 >1ZFJ-A nrPDB Length = 491 Score = 30.0 bits (66), Expect = 1.4, Method: Compositional matrix adjust. Identities = 26/107 (24%), Positives = 50/107 (46%), Gaps = 13/107 (12%) Query: 213 QMLTQGRVSSVPIID--ENGYLINVYEAYDVLGLIKGGIYNDLSLSVGEALMRRSDDFEG 270 +++ + R+S VPI++ N L+ + D+ +D + + E + E Sbjct: 114 ELMQRYRISGVPIVETLANRKLVGIITNRDMR------FISDYNAPISEHMTS-----EH 162 Query: 271 VYTCTKNDKLSTIMDNIRKARVHRFFVVDDVGRLVGVLTLSDILKYI 317 + T L T + + R+ + +VD+ GRL G++T+ DI K I Sbjct: 163 LVTAAVGTDLETAERILHEHRIEKLPLVDNSGRLSGLITIKDIEKVI 209 >4HG0-A nrPDB Length = 292 Score = 29.3 bits (64), Expect = 2.1, Method: Compositional matrix adjust. Identities = 26/121 (21%), Positives = 57/121 (47%), Gaps = 14/121 (11%) Query: 199 MKSCQMTTPVIDVIQMLTQGRVSSVPIIDEN-GYLINVYEAYDVLGLIKGGIYNDLSLSV 257 +K Q +DVI + S P+I E+ ++ + A D+L ++ +D Sbjct: 82 LKRNQTLDECLDVI---IESAHSRFPVISEDKDHIEGILMAKDLLPFMR----SDAEAFS 134 Query: 258 GEALMRRSDDFEGVYTCTKNDKLSTIMDNIRKARVHRFFVVDDVGRLVGVLTLSDILKYI 317 + ++R++ ++ ++ ++ R R H V+D+ G + G++T+ DIL+ I Sbjct: 135 MDKVLRQA------VVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELI 188 Query: 318 L 318 + Sbjct: 189 V 189 >5MIA-A nrPDB Length = 546 Score = 28.9 bits (63), Expect = 2.8, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 4/64 (6%) Query: 160 IVVSVLTQYRILKFVALNCRETHFLKIPIGDLNIITQDNMKSCQMTTPVIDVIQMLTQGR 219 I V +YR ++ V+++C + I D+ II D + S Q+T +D IQ+ R Sbjct: 210 ITVQSGKRYR-MRLVSISCDPNYLFSIDGHDMTIIEVDGVNSQQLT---VDQIQIFAAQR 265 Query: 220 VSSV 223 S V Sbjct: 266 YSFV 269 >3TSB-A nrPDB Length = 511 Score = 28.9 bits (63), Expect = 2.9, Method: Compositional matrix adjust. Identities = 45/212 (21%), Positives = 99/212 (46%), Gaps = 24/212 (11%) Query: 24 KFLNSKTSYD-VLPVSYRLIVLDTSLLVKKSLNVLLQNSI--VSAPLWDSKTSRFAGLLT 80 KF+ ++D VL V + VL + VK L+ LQ +I +SA + + A + Sbjct: 29 KFVKEGLTFDDVLLVPAKSDVLPREVSVKTVLSESLQLNIPLISAGMDTVTEADMAIAMA 88 Query: 81 TTDFINVIQYYFSNPDKFELVDKLQLDGLKDIERALGVDQLDTASIHPSRPLFEACLKML 140 + +I S + E VDK ++R+ D + P +++A M Sbjct: 89 RQGGLGIIHKNMSIEQQAEQVDK--------VKRSESGVISDPFFLTPEHQVYDAEHLMG 140 Query: 141 ESRSGRIPLIDQDEETHREIVVSVLTQYRILKFVALNCRETHFLKIPIGDLNIITQDNMK 200 + R +P+++ +E +V ++T R ++F+ + + +KI +++T++ + Sbjct: 141 KYRISGVPVVNNLDERK---LVGIITN-RDMRFI-----QDYSIKIS----DVMTKEQLI 187 Query: 201 SCQMTTPVIDVIQMLTQGRVSSVPIIDENGYL 232 + + T + + ++L + ++ +P++D NG L Sbjct: 188 TAPVGTTLSEAEKILQKYKIEKLPLVDNNGVL 219 >6GIQ-f nrPDB Length = 148 Score = 28.9 bits (63), Expect = 3.0, Method: Compositional matrix adjust. Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 8/73 (10%) Query: 50 VKKSLNVLLQNSIVSAPLWDSKTSRFA----GLLTTTDFINVIQYYFSNPDKFELVDKLQ 105 V++ LN +V AP K R A L T ++Y N D++ K Sbjct: 69 VQRVLNNCFSYDLVPAPAVIEKALRAARRVNDLPTAIRVFEALKYKVENEDQY----KAY 124 Query: 106 LDGLKDIERALGV 118 LD LKD+ + LGV Sbjct: 125 LDELKDVRQELGV 137 >6HU9-f nrPDB Length = 108 Score = 28.9 bits (63), Expect = 3.1, Method: Compositional matrix adjust. Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 8/73 (10%) Query: 50 VKKSLNVLLQNSIVSAPLWDSKTSRFA----GLLTTTDFINVIQYYFSNPDKFELVDKLQ 105 V++ LN +V AP K R A L T ++Y N D++ K Sbjct: 29 VQRVLNNCFSYDLVPAPAVIEKALRAARRVNDLPTAIRVFEALKYKVENEDQY----KAY 84 Query: 106 LDGLKDIERALGV 118 LD LKD+ + LGV Sbjct: 85 LDELKDVRQELGV 97 >2RGH-A nrPDB Length = 571 Score = 28.5 bits (62), Expect = 3.8, Method: Compositional matrix adjust. Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 7/80 (8%) Query: 239 YDVLGLIKGGIYNDLSLSVGEALMR----RSDDFEG--VYTCTKNDKLSTIMDNIRKARV 292 YD L + G Y + +L+ E L R + + +G VY +N+ ++DNI+KA Sbjct: 141 YDKLANVTGTKYENYTLTPEEVLEREPFLKKEGLKGAGVYLDFRNNDARLVIDNIKKAAE 200 Query: 293 HRFFVVDDVGRLVGVLTLSD 312 ++V + + VG L D Sbjct: 201 DGAYLVSKM-KAVGFLYEGD 219 >2RGO-A nrPDB Length = 607 Score = 28.5 bits (62), Expect = 4.0, Method: Compositional matrix adjust. Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 7/80 (8%) Query: 239 YDVLGLIKGGIYNDLSLSVGEALMR----RSDDFEG--VYTCTKNDKLSTIMDNIRKARV 292 YD L + G Y + +L+ E L R + + +G VY +N+ ++DNI+KA Sbjct: 127 YDKLANVTGTKYENYTLTPEEVLEREPFLKKEGLKGAGVYLDFRNNDARLVIDNIKKAAE 186 Query: 293 HRFFVVDDVGRLVGVLTLSD 312 ++V + + VG L D Sbjct: 187 DGAYLVSKM-KAVGFLYEGD 205 >2YVX-A nrPDB Length = 473 Score = 28.1 bits (61), Expect = 5.3, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 11/67 (16%) Query: 259 EALMRRSDDFEG-----VYTCTKND-KLSTIMDNIRKAR-----VHRFFVVDDVGRLVGV 307 EAL R +D G Y + + ++ +R+A ++ +VVD+ GRL GV Sbjct: 147 EALARYEEDEAGGLMTPEYVAVREGMTVEEVLRFLRRAAPDAETIYYIYVVDEKGRLKGV 206 Query: 308 LTLSDIL 314 L+L D++ Sbjct: 207 LSLRDLI 213 >2YVZ-A nrPDB Length = 278 Score = 28.1 bits (61), Expect = 6.0, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 11/67 (16%) Query: 259 EALMRRSDDFEG-----VYTCTKND-KLSTIMDNIRKAR-----VHRFFVVDDVGRLVGV 307 EAL R +D G Y + + ++ +R+A ++ +VVD+ GRL GV Sbjct: 127 EALARYEEDEAGGLMTPEYVAVREGMTVEEVLRFLRRAAPDAETIYYIYVVDEKGRLKGV 186 Query: 308 LTLSDIL 314 L+L D++ Sbjct: 187 LSLRDLI 193 Score = 27.7 bits (60), Expect = 7.5, Method: Compositional matrix adjust. Identities = 11/18 (61%), Positives = 16/18 (88%) Query: 297 VVDDVGRLVGVLTLSDIL 314 VVD+ GRLVG++T+ D+L Sbjct: 235 VVDEEGRLVGIVTVDDVL 252 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3TE5-C nrPDB 481 e-136 2OOY-G nrPDB 449 e-127 6B2E-C nrPDB 404 e-113 2UV7-A nrPDB 206 9e-54 Sequences not found previously or not previously below threshold: 1ZFJ-A nrPDB 53 2e-07 2CU0-A nrPDB 48 7e-06 3TSB-A nrPDB 46 2e-05 4FXS-A nrPDB 46 3e-05 1VRD-A nrPDB 43 2e-04 4AF0-B nrPDB 40 0.002 2YVX-A nrPDB 32 0.31 2YVZ-A nrPDB 32 0.43 4HG0-A nrPDB 32 0.54 5KQV-E nrPDB 32 0.55 4ZXB-E nrPDB 32 0.55 2HR7-A nrPDB 32 0.55 2C9K-A nrPDB 31 0.64 3PC3-A nrPDB 30 1.1 4DQW-A nrPDB 30 1.7 5OHX-A nrPDB 29 2.6 1JCN-A nrPDB 29 3.5 3L5A-A nrPDB 28 3.8 4FZC-A nrPDB 28 7.1 3F9R-A nrPDB 28 7.5 1AK5-A nrPDB 27 9.4 1ZI7-A nrPDB 27 9.5 1VR9-A nrPDB 27 9.5 >3TE5-C nrPDB Length = 323 Score = 481 bits (1239), Expect = e-136, Method: Composition-based stats. Identities = 321/321 (100%), Positives = 321/321 (100%) Query: 2 KPTQDSQEKVSIEQQLAVESIRKFLNSKTSYDVLPVSYRLIVLDTSLLVKKSLNVLLQNS 61 KPTQDSQEKVSIEQQLAVESIRKFLNSKTSYDVLPVSYRLIVLDTSLLVKKSLNVLLQNS Sbjct: 3 KPTQDSQEKVSIEQQLAVESIRKFLNSKTSYDVLPVSYRLIVLDTSLLVKKSLNVLLQNS 62 Query: 62 IVSAPLWDSKTSRFAGLLTTTDFINVIQYYFSNPDKFELVDKLQLDGLKDIERALGVDQL 121 IVSAPLWDSKTSRFAGLLTTTDFINVIQYYFSNPDKFELVDKLQLDGLKDIERALGVDQL Sbjct: 63 IVSAPLWDSKTSRFAGLLTTTDFINVIQYYFSNPDKFELVDKLQLDGLKDIERALGVDQL 122 Query: 122 DTASIHPSRPLFEACLKMLESRSGRIPLIDQDEETHREIVVSVLTQYRILKFVALNCRET 181 DTASIHPSRPLFEACLKMLESRSGRIPLIDQDEETHREIVVSVLTQYRILKFVALNCRET Sbjct: 123 DTASIHPSRPLFEACLKMLESRSGRIPLIDQDEETHREIVVSVLTQYRILKFVALNCRET 182 Query: 182 HFLKIPIGDLNIITQDNMKSCQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDV 241 HFLKIPIGDLNIITQDNMKSCQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDV Sbjct: 183 HFLKIPIGDLNIITQDNMKSCQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDV 242 Query: 242 LGLIKGGIYNDLSLSVGEALMRRSDDFEGVYTCTKNDKLSTIMDNIRKARVHRFFVVDDV 301 LGLIKGGIYNDLSLSVGEALMRRSDDFEGVYTCTKNDKLSTIMDNIRKARVHRFFVVDDV Sbjct: 243 LGLIKGGIYNDLSLSVGEALMRRSDDFEGVYTCTKNDKLSTIMDNIRKARVHRFFVVDDV 302 Query: 302 GRLVGVLTLSDILKYILLGSN 322 GRLVGVLTLSDILKYILLGSN Sbjct: 303 GRLVGVLTLSDILKYILLGSN 323 >2OOY-G nrPDB Length = 333 Score = 449 bits (1154), Expect = e-127, Method: Composition-based stats. Identities = 158/307 (51%), Positives = 225/307 (73%), Gaps = 3/307 (0%) Query: 15 QQLAVESIRKFLNSKTSYDVLPVSYRLIVLDTSLLVKKSLNVLLQNSIVSAPLWDSKTSR 74 Q+ A++ I+ F+ S+TSYDVLP S+RLIV D +L VK SL++L N+IVSAPLWDS+ ++ Sbjct: 7 QKGALKEIQAFIRSRTSYDVLPTSFRLIVFDVTLFVKTSLSLLTLNNIVSAPLWDSEANK 66 Query: 75 FAGLLTTTDFINVIQYYF---SNPDKFELVDKLQLDGLKDIERALGVDQLDTASIHPSRP 131 FAGLLT DF+NVI+YY+ S P+ +DK +L GL+++ER +G +T +HP Sbjct: 67 FAGLLTMADFVNVIKYYYQSSSFPEAIAEIDKFRLLGLREVERKIGAIPPETIYVHPMHS 126 Query: 132 LFEACLKMLESRSGRIPLIDQDEETHREIVVSVLTQYRILKFVALNCRETHFLKIPIGDL 191 L +ACL M +SR+ RIPLID D ET E++VSVLTQYRILKF+++NC+ET L++P+ + Sbjct: 127 LMDACLAMSKSRARRIPLIDVDGETGSEMIVSVLTQYRILKFISMNCKETAMLRVPLNQM 186 Query: 192 NIITQDNMKSCQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDVLGLIKGGIYN 251 I T N+ + M T V DVI+ML + +S+VPI++ G L+NVYE+ DV+ LI+ G Y+ Sbjct: 187 TIGTWSNLATASMETKVYDVIKMLAEKNISAVPIVNSEGTLLNVYESVDVMHLIQDGDYS 246 Query: 252 DLSLSVGEALMRRSDDFEGVYTCTKNDKLSTIMDNIRKARVHRFFVVDDVGRLVGVLTLS 311 +L LSVGEAL++R +F+GV+TC D+L I D I+ +RVHR FVVD+ +L G+L+L+ Sbjct: 247 NLDLSVGEALLKRPANFDGVHTCRATDRLDGIFDAIKHSRVHRLFVVDENLKLEGILSLA 306 Query: 312 DILKYIL 318 DIL YI+ Sbjct: 307 DILNYII 313 >6B2E-C nrPDB Length = 336 Score = 404 bits (1039), Expect = e-113, Method: Composition-based stats. Identities = 113/303 (37%), Positives = 175/303 (57%), Gaps = 16/303 (5%) Query: 24 KFLNSKTSYDVLPVSYRLIVLDTSLLVKKSLNVLLQNSIVSAPLWDSKTSRFAGLLTTTD 83 F+ S YD++P S +L+V DTSL VKK+ L+ N + +APLWDSK F G+LT TD Sbjct: 36 SFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITD 95 Query: 84 FINVIQYYFSNPDKFELVDKLQLDGLKDIERALGVDQLDT----ASIHPSRPLFEACLKM 139 FIN++ Y+ K LV +L+ K IE V D+ I P+ LF+A + Sbjct: 96 FINILHRYY----KSALVQIYELEEHK-IETWREVYLQDSFKPLVCISPNASLFDAVSSL 150 Query: 140 LESRSGRIPLIDQDEETHREIVVSVLTQYRILKFVALNCRE---THFLKIPIGDLNIITQ 196 + ++ R+P+ID + + +LT RILKF+ L E F+ + +L I T Sbjct: 151 IRNKIHRLPVIDPESGN----TLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTY 206 Query: 197 DNMKSCQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDVLGLIKGGIYNDLSLS 256 N+ + TTPV + + Q RVS++P++DE G ++++Y +DV+ L YN+L +S Sbjct: 207 ANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVS 266 Query: 257 VGEALMRRSDDFEGVYTCTKNDKLSTIMDNIRKARVHRFFVVDDVGRLVGVLTLSDILKY 316 V +AL RS FEGV C ++ L TI++ + +A VHR VVD+ + G+++LSDIL+ Sbjct: 267 VTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQA 326 Query: 317 ILL 319 ++L Sbjct: 327 LVL 329 >2UV7-A nrPDB Length = 152 Score = 206 bits (525), Expect = 9e-54, Method: Composition-based stats. Identities = 51/140 (36%), Positives = 86/140 (61%) Query: 180 ETHFLKIPIGDLNIITQDNMKSCQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAY 239 + F+ + +L I T N+ + TTPV + + Q RVS++P++DE G ++++Y + Sbjct: 12 KPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKF 71 Query: 240 DVLGLIKGGIYNDLSLSVGEALMRRSDDFEGVYTCTKNDKLSTIMDNIRKARVHRFFVVD 299 DV+ L YN+L +SV +AL RS FEGV C ++ L TI++ + +A VH VVD Sbjct: 72 DVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHGLVVVD 131 Query: 300 DVGRLVGVLTLSDILKYILL 319 + + G+++LSDIL+ ++L Sbjct: 132 ENDVVKGIVSLSDILQALVL 151 >1ZFJ-A nrPDB Length = 491 Score = 53.1 bits (126), Expect = 2e-07, Method: Composition-based stats. Identities = 54/309 (17%), Positives = 122/309 (39%), Gaps = 41/309 (13%) Query: 24 KFLNSKTSYD---VLPVSYRLIVLDTSLLVKKSLNVLLQNSIVSAPLWDSKTSRFAGLLT 80 KFL ++D ++P ++ + L K + N+ L I++A + S+ A + Sbjct: 6 KFLKKGYTFDDVLLIPAESHVLPNEVDLKTKLADNLTLNIPIITAAMDTVTGSKMAIAIA 65 Query: 81 TTDFINVIQYYFSNPDKFELVDKLQLDGLKDIERALGVDQLDTASIHPSRPLFEACLKML 140 + VI S ++ E V + ++R+ +D + P + EA M Sbjct: 66 RAGGLGVIHKNMSITEQAEEV--------RKVKRSENGVIIDPFFLTPEHKVSEAEELMQ 117 Query: 141 ESRSGRIPLIDQDEETHREIVVSVLTQYRILKFVALNCRETHFLKIPIGDLNIITQDNMK 200 R +P++ E +V ++T R ++F++ PI + T +++ Sbjct: 118 RYRISGVPIV---ETLANRKLVGIITN-RDMRFISDY-------NAPISEHM--TSEHLV 164 Query: 201 SCQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDVLGLIK---------GGIYN 251 + + T + ++L + R+ +P++D +G L + D+ +I+ G + Sbjct: 165 TAAVGTDLETAERILHEHRIEKLPLVDNSGRLSGLITIKDIEKVIEFPHAAKDEFGRLLV 224 Query: 252 DLSLSVGEALMRRSDDF-----EGVYTCTKNDKLSTIMDNIRKARVH---RFFVVDDVGR 303 ++ V R++ + + T + + ++ I + R H R + ++ Sbjct: 225 AAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPNRTLIAGNIAT 284 Query: 304 LVGVLTLSD 312 G L D Sbjct: 285 AEGARALYD 293 Score = 34.6 bits (78), Expect = 0.065, Method: Composition-based stats. Identities = 27/115 (23%), Positives = 52/115 (45%), Gaps = 13/115 (11%) Query: 205 TTPVIDVIQMLTQGRVSSVPIIDE--NGYLINVYEAYDVLGLIKGGIYNDLSLSVGEALM 262 V + +++ + R+S VPI++ N L+ + D+ +D + + E + Sbjct: 106 EHKVSEAEELMQRYRISGVPIVETLANRKLVGIITNRDM------RFISDYNAPISEHMT 159 Query: 263 RRSDDFEGVYTCTKNDKLSTIMDNIRKARVHRFFVVDDVGRLVGVLTLSDILKYI 317 E + T L T + + R+ + +VD+ GRL G++T+ DI K I Sbjct: 160 S-----EHLVTAAVGTDLETAERILHEHRIEKLPLVDNSGRLSGLITIKDIEKVI 209 >2CU0-A nrPDB Length = 486 Score = 47.7 bits (112), Expect = 7e-06, Method: Composition-based stats. Identities = 48/236 (20%), Positives = 92/236 (38%), Gaps = 32/236 (13%) Query: 19 VESIRKFLNSKTSYDVL--PVSYRLIVLDTSLLVKKSLNVLLQNSIVSAPLWDSKTSRFA 76 VE + K + T DVL P + + D + + + NV L I+SA + A Sbjct: 5 VEKLEKAIKGYTFDDVLLIPQATEVEPKDVDVSTRITPNVKLNIPILSAAMDTVTEWEMA 64 Query: 77 GLLTTTDFINVIQYYFSNPDKFELVDKLQLDGLKDIERALGVDQLDTASIHPSRPLFEAC 136 + + VI ++ E V K ++RA + D +I P + A Sbjct: 65 VAMAREGGLGVIHRNMGIEEQVEQV--------KRVKRAERLIVEDVITIAPDETVDFAL 116 Query: 137 LKMLESRSGRIPLIDQDEETHREIVVSVLTQYRILKFVALNCRETHFLKIPIGDLNIITQ 196 M + +P+++ E VV ++T+ I RE +K + I Sbjct: 117 FLMEKHGIDGLPVVE------DEKVVGIITKKDIA------AREGKLVKELMTKEVI--- 161 Query: 197 DNMKSCQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDVLGLIKGGIYND 252 + + V + ++++ + R+ +P++DE G L+ + D L+ Y + Sbjct: 162 ----TVPESIEVEEALKIMIENRIDRLPVVDERGKLVGLITMSD---LVARKKYKN 210 Score = 37.3 bits (85), Expect = 0.009, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 50/104 (48%), Gaps = 15/104 (14%) Query: 211 VIQMLTQGRVSSVPIIDENGYLINVYEAYDVLGLIKGGIYNDLSLSVGEALMRRSDDFEG 270 + ++ + + +P++++ V+G+I + + LM + Sbjct: 115 ALFLMEKHGIDGLPVVEDE----------KVVGIITKKDIAAREGKLVKELMTKE----- 159 Query: 271 VYTCTKNDKLSTIMDNIRKARVHRFFVVDDVGRLVGVLTLSDIL 314 V T ++ ++ + + + R+ R VVD+ G+LVG++T+SD++ Sbjct: 160 VITVPESIEVEEALKIMIENRIDRLPVVDERGKLVGLITMSDLV 203 Score = 31.9 bits (71), Expect = 0.38, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 42/80 (52%), Gaps = 1/80 (1%) Query: 40 RLIVLDTSLLVKKSLNVLLQNSIVSAPLWDSKTSRFAGLLTTTDFINVIQYYFSNPDKFE 99 +I + S+ V+++L ++++N I P+ D + + GL+T +D + +Y + D+ Sbjct: 159 EVITVPESIEVEEALKIMIENRIDRLPVVD-ERGKLVGLITMSDLVARKKYKNAVRDENG 217 Query: 100 LVDKLQLDGLKDIERALGVD 119 + DI+RA+ +D Sbjct: 218 ELLVAAAVSPFDIKRAIELD 237 >3TSB-A nrPDB Length = 511 Score = 46.2 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 53/285 (18%), Positives = 119/285 (41%), Gaps = 38/285 (13%) Query: 24 KFLNSKTSYD-VLPVSYRLIVLDTSLLVKKSLNVLLQNSI--VSAPLWDSKTSRFAGLLT 80 KF+ ++D VL V + VL + VK L+ LQ +I +SA + + A + Sbjct: 29 KFVKEGLTFDDVLLVPAKSDVLPREVSVKTVLSESLQLNIPLISAGMDTVTEADMAIAMA 88 Query: 81 TTDFINVIQYYFSNPDKFELVDKLQLDGLKDIERALGVDQLDTASIHPSRPLFEACLKML 140 + +I S + E VDK ++R+ D + P +++A M Sbjct: 89 RQGGLGIIHKNMSIEQQAEQVDK--------VKRSESGVISDPFFLTPEHQVYDAEHLMG 140 Query: 141 ESRSGRIPLIDQDEETHREIVVSVLTQYRILKFVALNCRETHFLKIPIGDLNIITQDNMK 200 + R +P+++ +E +V ++T R ++F+ I +++T++ + Sbjct: 141 KYRISGVPVVNNLDE---RKLVGIITN-RDMRFIQ---------DYSIKISDVMTKEQLI 187 Query: 201 SCQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDVLGLI---------KGGIYN 251 + + T + + ++L + ++ +P++D NG L + D+ +I +G + Sbjct: 188 TAPVGTTLSEAEKILQKYKIEKLPLVDNNGVLQGLITIKDIEKVIEFPNSAKDKQGRLLV 247 Query: 252 DLSLSVGEALMRR-----SDDFEGVYTCTKNDKLSTIMDNIRKAR 291 ++ V M R + + T + ++D +++ R Sbjct: 248 GAAVGVTADAMTRIDALVKASVDAIVLDTAHGHSQGVIDKVKEVR 292 Score = 40.8 bits (94), Expect = 9e-04, Method: Composition-based stats. Identities = 24/115 (20%), Positives = 48/115 (41%), Gaps = 13/115 (11%) Query: 205 TTPVIDVIQMLTQGRVSSVPIID--ENGYLINVYEAYDVLGLIKGGIYNDLSLSVGEALM 262 V D ++ + R+S VP+++ + L+ + D + I+ + E L+ Sbjct: 129 EHQVYDAEHLMGKYRISGVPVVNNLDERKLVGIITNRD-MRFIQDYSIKISDVMTKEQLI 187 Query: 263 RRSDDFEGVYTCTKNDKLSTIMDNIRKARVHRFFVVDDVGRLVGVLTLSDILKYI 317 LS ++K ++ + +VD+ G L G++T+ DI K I Sbjct: 188 TAP----------VGTTLSEAEKILQKYKIEKLPLVDNNGVLQGLITIKDIEKVI 232 >4FXS-A nrPDB Length = 496 Score = 45.8 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 36/210 (17%), Positives = 82/210 (39%), Gaps = 18/210 (8%) Query: 115 ALGVDQLDTASIHPSRPLF-----EACLKMLESRSGRIPLIDQDEETHREIVVSV-LTQY 168 A D + P+ + ++ ++ + IP++ +T E +++ L Q Sbjct: 7 AKEALTFDDVLLVPAHSTVLPNTADLRTRLTKNIALNIPMVSASMDTVTEARLAIALAQE 66 Query: 169 RILKFV--ALNCRETHFLKIPIGDLNIITQDNMKSCQMTTPVIDVIQMLTQGRVSSVPII 226 + F+ ++ + + + + + + DV+++ + P++ Sbjct: 67 GGIGFIHKNMSIEQQAAQVHQVKIFEAGVVTHPVTVRPEQTIADVMELTHYHGFAGFPVV 126 Query: 227 DENGYLINVYEAYDVLGLIKGGIYNDLSLSVGEALMRRSDDFEGVYTCTKNDKLSTIMDN 286 EN L+ + DV DL+ SV + + E + T + + + + Sbjct: 127 TENNELVGIITGRDV------RFVTDLTKSVAAVMTPK----ERLATVKEGATGAEVQEK 176 Query: 287 IRKARVHRFFVVDDVGRLVGVLTLSDILKY 316 + KARV + VV+D +L G++T D K Sbjct: 177 MHKARVEKILVVNDEFQLKGMITAKDFHKA 206 >1VRD-A nrPDB Length = 494 Score = 43.1 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 23/117 (19%), Positives = 52/117 (44%), Gaps = 10/117 (8%) Query: 201 SCQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDVLGLIKGGIYNDLSLSVGEA 260 + V + I ++ + ++ +P++DE G L+ + DV +LS + + Sbjct: 107 TVTPDMTVKEAIDLMAEYKIGGLPVVDEEGRLVGLLTNRDV------RFEKNLSKKIKDL 160 Query: 261 LMRRSDDFEGVYTCTKNDKLSTIMDNIRKARVHRFFVVDDVGRLVGVLTLSDILKYI 317 + R E + + L + + + R+ + +V +LVG++T+ DI+ I Sbjct: 161 MTPR----EKLIVAPPDISLEKAKEILHQHRIEKLPLVSKDNKLVGLITIKDIMSVI 213 Score = 42.3 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 35/213 (16%), Positives = 85/213 (39%), Gaps = 22/213 (10%) Query: 34 VLPVSYRLIVLDTSLLVKKSLNVLLQNSIVSAPLWDSKTSRFAGLLTTTDFINVIQYYFS 93 ++P ++ D + + + + + +VSA + + A L I +I + Sbjct: 24 LVPQYSEVLPKDVKIDTRLTRQIRINIPLVSAAMDTVTEAALAKALAREGGIGIIHKNLT 83 Query: 94 NPDKFELVDKLQLDGLKDIERALGVDQLDTASIHPSRPLFEACLKMLESRSGRIPLIDQD 153 ++ V +++ D ++ P + EA M E + G +P++D++ Sbjct: 84 PDEQARQVSI--------VKKTENGIIYDPITVTPDMTVKEAIDLMAEYKIGGLPVVDEE 135 Query: 154 EETHREIVVSVLTQYRILKFVALNCRETHFLKIPIGDLNIITQDNMKSCQMTTPVIDVIQ 213 +V +LT R ++F ++ L P L + D + + Sbjct: 136 GR-----LVGLLTN-RDVRFEKNLSKKIKDLMTPREKLIVAPPD--------ISLEKAKE 181 Query: 214 MLTQGRVSSVPIIDENGYLINVYEAYDVLGLIK 246 +L Q R+ +P++ ++ L+ + D++ +I+ Sbjct: 182 ILHQHRIEKLPLVSKDNKLVGLITIKDIMSVIE 214 >4AF0-B nrPDB Length = 556 Score = 39.6 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 35/229 (15%), Positives = 86/229 (37%), Gaps = 29/229 (12%) Query: 21 SIRKFLNSKTS-------YDVLPVSYRLIVLDTSLLVKKSLNVLLQNSIVSAPLWDSKTS 73 S+++ ++S+ + + VLP D SL K + N++L +S+P+ Sbjct: 47 SLQELMDSRKNGGLTYNDFLVLPGHINFPASDVSLQSKATKNIVLNTPFLSSPMDTVTED 106 Query: 74 RFAGLLTTTDFINVIQYYFSNPDKFELVDKLQLDGLKDIERALGVDQLDTASIHPSRPLF 133 R A L + +I + S ++ +V + +++ D + P + Sbjct: 107 RMAIALALHGGLGIIHHNCSAEEQAAMV--------RRVKKYENGFITDPLCLGPDATVG 158 Query: 134 EACLKMLESRSGRIPLIDQDEETHREIVVSVLTQYRILKFVALNCRETHFLKIPIGDLNI 193 + ++++ G + + ++ ++T V ET + ++ Sbjct: 159 DVLE--IKAKFGFCGVPITETGEPDSKLLGIVTGRD----VQFQDAETPIKSVMTTEVVT 212 Query: 194 ITQDNMKSCQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDVL 242 + +L + + +PI+D NG+L+++ D+L Sbjct: 213 G--------SSPITLEKANSLLRETKKGKLPIVDSNGHLVSLVARSDLL 253 >2YVX-A nrPDB Length = 473 Score = 32.3 bits (72), Expect = 0.31, Method: Composition-based stats. Identities = 11/52 (21%), Positives = 26/52 (50%) Query: 202 CQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDVLGLIKGGIYNDL 253 + T +V +++ + +P++DE G L+ + DVL +++ D+ Sbjct: 232 VRTDTDQEEVARLMADYDFTVLPVVDEEGRLVGIVTVDDVLDVLEAEATEDI 283 Score = 28.8 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 11/23 (47%), Positives = 18/23 (78%) Query: 292 VHRFFVVDDVGRLVGVLTLSDIL 314 ++ +VVD+ GRL GVL+L D++ Sbjct: 191 IYYIYVVDEKGRLKGVLSLRDLI 213 >2YVZ-A nrPDB Length = 278 Score = 31.5 bits (70), Expect = 0.43, Method: Composition-based stats. Identities = 11/52 (21%), Positives = 26/52 (50%) Query: 202 CQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDVLGLIKGGIYNDL 253 + T +V +++ + +P++DE G L+ + DVL +++ D+ Sbjct: 212 VRTDTDQEEVARLMADYDFTVLPVVDEEGRLVGIVTVDDVLDVLEAEATEDI 263 Score = 28.5 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 11/23 (47%), Positives = 18/23 (78%) Query: 292 VHRFFVVDDVGRLVGVLTLSDIL 314 ++ +VVD+ GRL GVL+L D++ Sbjct: 171 IYYIYVVDEKGRLKGVLSLRDLI 193 >4HG0-A nrPDB Length = 292 Score = 31.5 bits (70), Expect = 0.54, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 25/42 (59%) Query: 277 NDKLSTIMDNIRKARVHRFFVVDDVGRLVGVLTLSDILKYIL 318 + ++ ++ R R H V+D+ G + G++T+ DIL+ I+ Sbjct: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189 >5KQV-E nrPDB Length = 609 Score = 31.5 bits (70), Expect = 0.55, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 38/96 (39%), Gaps = 14/96 (14%) Query: 17 LAVESIRKFLNSKTSYDVLPVSY----RLIVLDTSLLVKKSLNVLLQNSIVSAPLWDSKT 72 +E I +L + SY ++ +S+ RLI +T + S L ++ LWD Sbjct: 359 GLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQ--LWDWSK 416 Query: 73 SRFAGLLTTTDFINVIQYYFSNPDKFELVDKLQLDG 108 LT T + +F K L + +++ Sbjct: 417 HN----LTITQG----KLFFHYNPKLCLSEIHKMEE 444 >4ZXB-E nrPDB Length = 894 Score = 31.5 bits (70), Expect = 0.55, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 38/96 (39%), Gaps = 14/96 (14%) Query: 17 LAVESIRKFLNSKTSYDVLPVSY----RLIVLDTSLLVKKSLNVLLQNSIVSAPLWDSKT 72 +E I +L + SY ++ +S+ RLI +T + S L ++ LWD Sbjct: 359 GLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQ--LWDWSK 416 Query: 73 SRFAGLLTTTDFINVIQYYFSNPDKFELVDKLQLDG 108 LT T + +F K L + +++ Sbjct: 417 HN----LTITQG----KLFFHYNPKLCLSEIHKMEE 444 >2HR7-A nrPDB Length = 486 Score = 31.5 bits (70), Expect = 0.55, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 38/96 (39%), Gaps = 14/96 (14%) Query: 17 LAVESIRKFLNSKTSYDVLPVSY----RLIVLDTSLLVKKSLNVLLQNSIVSAPLWDSKT 72 +E I +L + SY ++ +S+ RLI +T + S L ++ LWD Sbjct: 359 GLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQ--LWDWSK 416 Query: 73 SRFAGLLTTTDFINVIQYYFSNPDKFELVDKLQLDG 108 LT T + +F K L + +++ Sbjct: 417 HN----LTITQG----KLFFHYNPKLCLSEIHKMEE 444 >2C9K-A nrPDB Length = 612 Score = 31.2 bits (69), Expect = 0.64, Method: Composition-based stats. Identities = 31/139 (22%), Positives = 55/139 (39%), Gaps = 10/139 (7%) Query: 189 GDLNIITQDNMKSCQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDVLGLIKGG 248 G++N T N +MTT V+D++ + V PI ++ +Y+ VL + Sbjct: 218 GNINWNTY-NTYRTKMTTAVLDLVALFPNYDVGKYPIGVQSELTREIYQ---VLNF-EES 272 Query: 249 IYNDLSLSVGE-ALMRRSDDFEGVYTCTKNDKLSTIMDNIRKARVHRFFVVDDVGRLVGV 307 Y E +L RR F + + +K T +N + + F D Sbjct: 273 PYKYYDFQYQEDSLTRRPHLFTWLDSLNFYEKAQTTPNNFFTSHYNMFHYTLDNISQKSS 332 Query: 308 L----TLSDILKYILLGSN 322 + ++D LK + L +N Sbjct: 333 VFGNHNVTDKLKSLGLATN 351 >3PC3-A nrPDB Length = 527 Score = 30.4 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 20/105 (19%), Positives = 43/105 (40%), Gaps = 14/105 (13%) Query: 172 KFVALNCRETHFLKIPIGDLNIITQDNMKSCQMTTP-----------VIDVIQMLTQGRV 220 KFV+ N E K P+ + + ++ P V + I ++ + RV Sbjct: 358 KFVSDNWMEARNFKEPVNEHGHWWWS-LAIAELELPAPPVILKSDATVGEAIALMKKHRV 416 Query: 221 SSVPIIDE-NGYLINVYEAYDVLGLIKGGIYNDLSLSVGEALMRR 264 +P++D+ +G ++ V ++ I ++ +AL +R Sbjct: 417 DQLPVVDQDDGSVLGVVGQETLITQIVSMNRQQSDPAI-KALNKR 460 >4DQW-A nrPDB Length = 509 Score = 29.6 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 40/209 (19%), Positives = 83/209 (39%), Gaps = 25/209 (11%) Query: 34 VLPVSYRLIVLDTSLLVKKSLNVLLQNSIVSAPLWDSKTSRFAGLLTTTDFINVIQYYFS 93 ++P ++ D SL + + + L +VSA + +R A + I +I Sbjct: 36 LIPGYSEVLPKDVSLKTRLTRGIELNIPLVSAAMDTVTEARLAIAMAQEGGIGIIHKNMG 95 Query: 94 NPDKFELVDKLQLDGLKDIERALGVDQLDTASIHPSRPLFEACLKMLESRSGRIPLIDQD 153 + V + +++ D ++ PS + E E P+++Q Sbjct: 96 IEQQAAEV--------RKVKKHETAIVRDPVTVTPSTKIIELLQMAREYGFSGFPVVEQG 147 Query: 154 EETHREIVVSVLTQYRILKFVALNCRET-HFLKIPIGDLNIITQDNMKSCQMTTPVIDVI 212 E +V ++T R L+ V N +T + P +D + + + TP+ ++ Sbjct: 148 E------LVGIVTG-RDLR-VKPNAGDTVAAIMTP--------KDKLVTAREGTPLEEMK 191 Query: 213 QMLTQGRVSSVPIIDENGYLINVYEAYDV 241 L + R+ + ++DEN YL + D+ Sbjct: 192 AKLYENRIEKMLVVDENFYLRGLVTFRDI 220 >5OHX-A nrPDB Length = 504 Score = 29.2 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 9/37 (24%), Positives = 19/37 (51%) Query: 284 MDNIRKARVHRFFVVDDVGRLVGVLTLSDILKYILLG 320 M ++ A + DD + GV++L+ + Y++ G Sbjct: 394 MHMLKNADSQLLVISDDNIHIKGVISLNKLTSYVISG 430 >1JCN-A nrPDB Length = 514 Score = 28.8 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 22/147 (14%), Positives = 56/147 (38%), Gaps = 12/147 (8%) Query: 104 LQLDGLKDIERALGVDQLDTASIHPSRPLFEACLKMLESRSGRIPLIDQDEETHREIVVS 163 Q + ++ ++ D + PS + + + IP+ + T +V Sbjct: 99 FQANEVRKVKNFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPI--TETGTMGSKLVG 156 Query: 164 VLTQYRILKFVALNCRETHFLKIPIGDLNIITQDNMKSCQMTTPVIDVIQMLTQGRVSSV 223 ++T R + F+A T ++ + ++ + +T + ++L + + + Sbjct: 157 IVTS-RDIDFLAEKDHTTLLSEVMTPRIELV----VAPAGVTLK--EANEILQRSKKGKL 209 Query: 224 PIIDENGYLINVYEAYDVLGLIKGGIY 250 PI+++ L+ + D L K Y Sbjct: 210 PIVNDCDELVAIIARTD---LKKNRDY 233 >3L5A-A nrPDB Length = 419 Score = 28.5 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 17/50 (34%) Query: 141 ESRSGRIPLIDQDEETHREIVVSVLTQYRILKFVALNCRETHFLKIPIGD 190 E +GRIPLI E + L ++ + E F+ Sbjct: 313 EHLAGRIPLIASGGINSPESALDALQHADMVGMSSPFVTEPDFVHKLAEQ 362 >4FZC-A nrPDB Length = 250 Score = 27.7 bits (60), Expect = 7.1, Method: Composition-based stats. Identities = 23/90 (25%), Positives = 32/90 (35%), Gaps = 10/90 (11%) Query: 52 KSLNVLLQNSIV-------SAPLWDSKTSRFAGLLTTTDFINVIQYYFSNPDKFELVDKL 104 SL + N +V S+PL S+T LLT D V Y PD LVDK Sbjct: 33 TSLGIKATNGVVIATEKKSSSPLAMSETLSKVSLLT-PDIGAV--YSGMGPDYRVLVDKS 89 Query: 105 QLDGLKDIERALGVDQLDTASIHPSRPLFE 134 + +R G + + + Sbjct: 90 RKVAHTSYKRIYGEYPPTKLLVSEVAKIMQ 119 >3F9R-A nrPDB Length = 246 Score = 27.7 bits (60), Expect = 7.5, Method: Composition-based stats. Identities = 28/138 (20%), Positives = 47/138 (34%), Gaps = 34/138 (24%) Query: 155 ETHREIVVSVLTQYRILKFVALNCRETHFLKIPIGDLNIITQDN------------MKSC 202 E HR+ +++ L RI+KFV R L IP+ + N ++ Sbjct: 80 EIHRQSLLNALGNDRIVKFVKKTLRLIADLDIPVQRGTFVEYRNGMINVSPIGRNCSQAE 139 Query: 203 QMTTPVIDVIQMLTQGRVSSVPIIDENGYLINV---YE-----AYDVLGLIKGGIYNDLS 254 + V D + RV + I + + Y ++DV + Y Sbjct: 140 RDEFEVYD-----NEHRVRASLIAELENSFPDFGLKYSIGGQISFDVFPVGWDKTY---- 190 Query: 255 LSVGEALMRRSDDFEGVY 272 L DDFE ++ Sbjct: 191 -----CLQFVEDDFEEIH 203 >1AK5-A nrPDB Length = 503 Score = 27.3 bits (59), Expect = 9.4, Method: Composition-based stats. Identities = 14/107 (13%), Positives = 49/107 (45%), Gaps = 10/107 (9%) Query: 126 IHPSRPLFEACLKMLESRSGRIPLIDQDEETHREIVVSVLTQYRILKFVALNCRETHFLK 185 + P + + L + + + + D+ T +++ ++TQ ++ +T Sbjct: 110 VKPDQTFAD-VLAISQRTTHNTVAV-TDDGTPHGVLLGLVTQRD----YPIDLTQTE--- 160 Query: 186 IPIGDLNIITQDNMKSCQMTTPVIDVIQMLTQGRVSSVPIIDENGYL 232 + D+ + + + T + + +++ + +++++PIID++ +L Sbjct: 161 TKVSDM-MTPFSKLVTAHQDTKLSEANKIIWEKKLNALPIIDDDQHL 206 >1ZI7-A nrPDB Length = 406 Score = 27.3 bits (59), Expect = 9.5, Method: Composition-based stats. Identities = 22/121 (18%), Positives = 45/121 (37%), Gaps = 20/121 (16%) Query: 149 LIDQDEETHREIVVSVLTQYRILKFVALNCRETHFL---KIPIG----DLNIITQDNMKS 201 LID + E+ + +T++ I + C L K P+ +L + +N + Sbjct: 44 LIDPEVESPELARMLAVTKWFISTLKSQYCSRNESLGSEKKPLNPFLGELFVGKWENKEH 103 Query: 202 CQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDVLGLIKGGIYNDLSLSVGEAL 261 + V+ Q+ V++ I ++ +K YN + S ++L Sbjct: 104 PEFGETVLLSEQVSHHPPVTAFSIFNDK-------------NKVKLQGYNQIKASFTKSL 150 Query: 262 M 262 M Sbjct: 151 M 151 >1VR9-A nrPDB Length = 213 Score = 27.3 bits (59), Expect = 9.5, Method: Composition-based stats. Identities = 9/24 (37%), Positives = 15/24 (62%) Query: 295 FFVVDDVGRLVGVLTLSDILKYIL 318 VVD+ RL G ++L D L+ ++ Sbjct: 106 LPVVDEEMRLKGAVSLHDFLEALI 129 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.318 0.136 0.353 Lambda K H 0.267 0.0420 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,501,903 Number of Sequences: 36641 Number of extensions: 440162 Number of successful extensions: 1300 Number of sequences better than 10.0: 33 Number of HSP's better than 10.0 without gapping: 28 Number of HSP's successfully gapped in prelim test: 30 Number of HSP's that attempted gapping in prelim test: 1212 Number of HSP's gapped (non-prelim): 82 length of query: 322 length of database: 10,336,785 effective HSP length: 97 effective length of query: 225 effective length of database: 6,782,608 effective search space: 1526086800 effective search space used: 1526086800 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 59 (27.3 bits)