BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P12544 (262 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1ORF-A nrPDB 484 e-137 1MZD-A nrPDB 211 3e-55 1FDP-A nrPDB 178 2e-45 1EUF-A nrPDB 167 4e-42 5FCR-A nrPDB 166 8e-42 1FI8-A nrPDB 164 3e-41 1IAU-A nrPDB 163 6e-41 1NN6-A nrPDB 160 4e-40 3TK9-A nrPDB 160 5e-40 3G01-A nrPDB 159 8e-40 3RP2-A nrPDB 156 9e-39 1UTJ-A nrPDB 150 5e-37 2RDL-A nrPDB 149 8e-37 5MS3-A nrPDB 147 3e-36 1KYN-A nrPDB 142 2e-34 2ZKS-A nrPDB 141 2e-34 1A0J-A nrPDB 141 3e-34 3QUM-P nrPDB 140 6e-34 2EEK-A nrPDB 140 8e-34 1TON-A nrPDB 137 4e-33 1AO5-A nrPDB 137 6e-33 4Q7Y-A nrPDB 136 7e-33 4AN7-A nrPDB 136 7e-33 5FXL-A nrPDB 136 1e-32 4NFE-A nrPDB 136 1e-32 1SGF-G nrPDB 134 6e-32 3E0N-B nrPDB 134 6e-32 3DFJ-A nrPDB 133 6e-32 1SPJ-A nrPDB 132 1e-31 1EKB-B nrPDB 132 1e-31 1NPM-A nrPDB 132 2e-31 1F7Z-A nrPDB 130 5e-31 4WWY-A nrPDB 130 5e-31 5UGG-A nrPDB 129 1e-30 4DGJ-A nrPDB 129 1e-30 1PPF-E nrPDB 127 4e-30 4DUR-A nrPDB 127 6e-30 1SGF-A nrPDB 127 7e-30 1AE5-A nrPDB 127 7e-30 6QHB-A nrPDB 126 9e-30 1FUJ-A nrPDB 124 5e-29 3W94-A nrPDB 123 8e-29 5ZFH-A nrPDB 123 9e-29 5C67-A nrPDB 121 4e-28 3BSQ-A nrPDB 121 4e-28 1BQY-A nrPDB 120 5e-28 1ELT-A nrPDB 120 6e-28 3T2N-A nrPDB 120 8e-28 1YC0-A nrPDB 119 9e-28 5TJX-A nrPDB 119 1e-27 2R0L-A nrPDB 119 1e-27 4E7N-A nrPDB 119 1e-27 1P57-B nrPDB 118 2e-27 2TLD-E nrPDB 117 4e-27 4XDE-A nrPDB 117 4e-27 3S9B-A nrPDB 117 5e-27 2V35-A nrPDB 117 6e-27 2BDH-A nrPDB 117 6e-27 1BRU-P nrPDB 116 8e-27 6I44-A nrPDB 116 1e-26 4GSO-A nrPDB 116 1e-26 2PSX-A nrPDB 114 3e-26 1X7A-C nrPDB 114 4e-26 2AIQ-A nrPDB 112 2e-25 1AZZ-A nrPDB 112 2e-25 4IGD-A nrPDB 112 2e-25 4DJZ-B nrPDB 111 3e-25 2CGA-A nrPDB 111 3e-25 3LC3-A nrPDB 111 3e-25 5GVT-A nrPDB 110 5e-25 1GVZ-A nrPDB 109 1e-24 4MPW-A nrPDB 108 3e-24 2OQ5-A nrPDB 107 6e-24 5XRF-A nrPDB 107 8e-24 1FON-A nrPDB 106 1e-23 1FXY-A nrPDB 105 2e-23 4H4F-A nrPDB 104 5e-23 1PYT-D nrPDB 104 5e-23 1FIZ-A nrPDB 103 5e-23 1OP0-A nrPDB 103 6e-23 3S69-A nrPDB 103 7e-23 1LTO-A nrPDB 103 1e-22 1FIW-A nrPDB 102 1e-22 5LPF-A nrPDB 102 2e-22 2F91-A nrPDB 100 9e-22 3P8G-A nrPDB 99 1e-21 1A5I-A nrPDB 98 4e-21 6AOD-C nrPDB 97 5e-21 2F83-A nrPDB 96 1e-20 5KWM-A nrPDB 94 8e-20 2PKA-B nrPDB 93 1e-19 2XXL-A nrPDB 92 2e-19 1PQ7-A nrPDB 92 3e-19 3F6U-H nrPDB 91 4e-19 1SI5-H nrPDB 91 5e-19 2JET-B nrPDB 90 1e-18 1KIG-H nrPDB 89 3e-18 1BDA-A nrPDB 88 4e-18 2OLG-A nrPDB 85 3e-17 5XW8-A nrPDB 84 7e-17 1SC8-U nrPDB 83 1e-16 4KKD-A nrPDB 83 1e-16 1C5M-D nrPDB 83 1e-16 1Q3X-A nrPDB 83 1e-16 3VGC-B nrPDB 83 2e-16 1ZJK-A nrPDB 82 2e-16 4IW4-E nrPDB 82 3e-16 4FXG-H nrPDB 82 3e-16 1YM0-A nrPDB 81 5e-16 5LHN-A nrPDB 80 6e-16 1EQ9-A nrPDB 80 7e-16 3H7T-A nrPDB 80 1e-15 4Z6A-H nrPDB 80 1e-15 5O32-I nrPDB 78 4e-15 3NXP-A nrPDB 78 4e-15 6BQM-A nrPDB 77 6e-15 3K65-B nrPDB 77 6e-15 2B9L-A nrPDB 77 6e-15 2XRC-A nrPDB 77 7e-15 4NZQ-A nrPDB 77 8e-15 1MKW-K nrPDB 76 2e-14 3I77-A nrPDB 75 2e-14 2OCV-B nrPDB 75 2e-14 1ETT-H nrPDB 75 3e-14 5TO3-B nrPDB 74 9e-14 1ELV-A nrPDB 73 1e-13 1VR1-H nrPDB 73 1e-13 5UBM-A nrPDB 73 2e-13 2FMJ-A nrPDB 72 2e-13 4LK4-A nrPDB 72 2e-13 4J1Y-A nrPDB 71 5e-13 2ASU-B nrPDB 70 1e-12 4X0L-C nrPDB 69 3e-12 3BEU-A nrPDB 68 3e-12 4WJG-C nrPDB 68 5e-12 4F4O-C nrPDB 66 1e-11 1AKS-B nrPDB 64 9e-11 1M9U-A nrPDB 64 9e-11 4BXW-A nrPDB 63 2e-10 2HLC-A nrPDB 62 4e-10 2KAI-A nrPDB 61 5e-10 1GPZ-A nrPDB 61 6e-10 3H7O-A nrPDB 60 7e-10 1MD7-A nrPDB 60 1e-09 2QY0-B nrPDB 60 1e-09 1BBR-H nrPDB 51 5e-07 1RIW-B nrPDB 50 8e-07 1EPT-B nrPDB 48 5e-06 2I6S-A nrPDB 45 4e-05 1DLE-A nrPDB 40 8e-04 2WIN-I nrPDB 40 9e-04 2OK5-A nrPDB 40 0.001 3H5C-B nrPDB 38 0.005 2JET-C nrPDB 38 0.005 3RU4-E nrPDB 38 0.005 3F1S-B nrPDB 38 0.005 2HNT-F nrPDB 37 0.007 2HNT-C nrPDB 35 0.030 1BBR-E nrPDB 33 0.12 4IM4-A nrPDB 30 1.6 4NES-A nrPDB 28 3.4 4HWF-A nrPDB 28 5.8 >1ORF-A nrPDB Length = 234 Score = 484 bits (1245), Expect = e-137, Method: Compositional matrix adjust. Identities = 232/234 (99%), Positives = 232/234 (99%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 60 Query: 89 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMC 148 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQL EKAKINKYVTILHLPKKGDDVKPGTMC Sbjct: 61 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDVKPGTMC 120 Query: 149 QVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSC 208 QVAGWGRTHNSASWSDTLREV ITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSC Sbjct: 121 QVAGWGRTHNSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSC 180 Query: 209 NGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKGAV 262 NGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKGAV Sbjct: 181 NGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKGAV 234 >1MZD-A nrPDB Length = 240 Score = 211 bits (536), Expect = 3e-55, Method: Compositional matrix adjust. Identities = 104/232 (44%), Positives = 148/232 (63%), Gaps = 8/232 (3%) Query: 28 KIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNL----NKRSQVILGAH 83 +IIGG EV+PHSRP+M + +C G LI WVLTAAHC + V+LGAH Sbjct: 2 EIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAH 61 Query: 84 SITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVK 143 S+++ E +KQ + +KK P+ + D+ L++L AK+NK+V +LH+ K ++ Sbjct: 62 SLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSK-TSLR 120 Query: 144 PGTMCQVAGWGRTH-NSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 202 GT C+V GWG T +S SDTLREV +T++ RK+CN +++YN +P I +MVCAG + Sbjct: 121 SGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAK 180 Query: 203 GGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 G +DSC GD+G PL+C+GVF + S G E CG PG+Y LL+KK+ WI Sbjct: 181 GQKDSCKGDAGGPLICKGVFHAIVSGGHE--CGVATKPGIYTLLTKKYQTWI 230 >1FDP-A nrPDB Length = 235 Score = 178 bits (452), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 95/230 (41%), Positives = 139/230 (60%), Gaps = 9/230 (3%) Query: 28 KIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHC---NLNKRSQVILGAHS 84 +I+GG E H+RPYM + L+ +C G L+A+ WVL+AAHC + + QV+LGAHS Sbjct: 7 RILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHS 66 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKP 144 +++ EP+K++ V + P+P P T + DL LLQL EKA + V L + DV P Sbjct: 67 LSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAP 126 Query: 145 GTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 204 GT+C VAGWG +++ D+L+ V + ++DR CN R H++ I ++CA S R Sbjct: 127 GTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDG--AITERLMCAESNR-- 182 Query: 205 RDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 RDSC GDSG PL+C GV GV + G CG+ + PG+Y ++ + WI Sbjct: 183 RDSCKGDSGGPLVCGGVLEGVVTSG-SRVCGNRKKPGIYTRVA-SYAAWI 230 >1EUF-A nrPDB Length = 227 Score = 167 bits (423), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 95/234 (40%), Positives = 134/234 (57%), Gaps = 13/234 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLD---RKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSI 85 IIGG+E PHSRPYM L + IC G L+ +D+VLTAAHC L V LGAH+I Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHC-LGSSINVTLGAHNI 59 Query: 86 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 E T+Q++ V++ P+P Y+ T D+ LL+L KA I V+ ++LP+ +VKPG Sbjct: 60 MERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAEVKPG 119 Query: 146 TMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 205 MC VAGWGR + +D L+EV++ + + C R F I +CAG + Sbjct: 120 MMCSVAGWGRLGVNMPSTDKLQEVDLEVQSEEKCIAR----FKNYIPFTQICAGDPSKRK 175 Query: 206 DSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 +S +GDSG PL+C GV +G+ S+G D P VY +S L+WI T++ Sbjct: 176 NSFSGDSGGPLVCNGVAQGIVSYGRN----DGTTPDVYTRIS-SFLSWIHSTMR 224 >5FCR-A nrPDB Length = 234 Score = 166 bits (420), Expect = 8e-42, Method: Compositional matrix adjust. Identities = 89/230 (38%), Positives = 136/230 (59%), Gaps = 10/230 (4%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHC----NLNKRSQVILGAHS 84 I+GG E H+RPYM + ++ +C G L+ + WVL+AAHC + QV+LGAHS Sbjct: 1 ILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHS 60 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKP 144 ++ EP K+ V+ P+P P + E DL L +L + A + +V L L + +V+P Sbjct: 61 LSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDKEVEP 120 Query: 145 GTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 204 GT+C VAGWG ++ D L ++ ++I++R CN R +++ V+ +NM+CA S R Sbjct: 121 GTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDG--VVTINMMCAESNR-- 176 Query: 205 RDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 RD+C GDSGSPL+C GV ++G CG+ + PGVY +S + WI Sbjct: 177 RDTCRGDSGSPLVCGDAVEGVVTWG-SRVCGNGKKPGVYTRVSSYRM-WI 224 >1FI8-A nrPDB Length = 228 Score = 164 bits (416), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 99/235 (42%), Positives = 136/235 (57%), Gaps = 13/235 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSL----DRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHS 84 IIGG+E PHSRPYM L + C G LI +D+VLTAAHC+ +K QV LGAH+ Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSK-IQVTLGAHN 59 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKP 144 I +E +QI+ V K P+P Y+ T D+ LL+L KAK + V L+LP++ VKP Sbjct: 60 IKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 119 Query: 145 GTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 204 G +C VAGWG+ +SDTL+EV +T+ + + C Y N N +CAG + Sbjct: 120 GDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCES---YLKNYFDKANEICAGDPKIK 176 Query: 205 RDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 R S GDSG PL+C+ V G+ S+G +N PR + +S L+WI T+K Sbjct: 177 RASFRGDSGGPLVCKKVAAGIVSYG-QNDGSTPR---AFTKVS-TFLSWIKKTMK 226 >1IAU-A nrPDB Length = 227 Score = 163 bits (413), Expect = 6e-41, Method: Compositional matrix adjust. Identities = 94/208 (45%), Positives = 122/208 (58%), Gaps = 9/208 (4%) Query: 29 IIGGNEVTPHSRPYMVLLSL-DRKTI--CAGALIAKDWVLTAAHCNLNKRSQVILGAHSI 85 IIGG+E PHSRPYM L + D+K++ C G LI D+VLTAAHC V LGAH+I Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-WGSSINVTLGAHNI 59 Query: 86 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 +EPT+Q + VK+ P+P Y+P D+ LLQL KAK + V L LP VKPG Sbjct: 60 KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 119 Query: 146 TMCQVAGWGRTHNSASWSDTLREVNITII-DRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 204 C VAGWG+T S TL+EV +T+ DRK +D HY ++ I + C G Sbjct: 120 QTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHY-YDSTIEL---CVGDPEIK 175 Query: 205 RDSCNGDSGSPLLCEGVFRGVTSFGLEN 232 + S GDSG PL+C V +G+ S+G N Sbjct: 176 KTSFKGDSGGPLVCNKVAQGIVSYGRNN 203 >1NN6-A nrPDB Length = 228 Score = 160 bits (406), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 94/231 (40%), Positives = 131/231 (56%), Gaps = 15/231 (6%) Query: 28 KIIGGNEVTPHSRPYMVLLSL----DRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAH 83 +IIGG E PHSRPYM L + C G LI +++VLTAAHC + V LGAH Sbjct: 2 EIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC-AGRSITVTLGAH 60 Query: 84 SITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVK 143 +IT EE T Q + V K+F +P Y+ +T D+ LL+L EKA + V L P + + V Sbjct: 61 NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVP 120 Query: 144 PGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRG 203 PG MC+VAGWGRT SDTL+EV + ++D + C+ ++ N +C G+ R Sbjct: 121 PGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHN-----LQLCVGNPRK 175 Query: 204 GRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 + + GDSG PLLC GV +G+ S+G D + P V+ +S + WI Sbjct: 176 TKSAFKGDSGGPLLCAGVAQGIVSYGRS----DAKPPAVFTRIS-HYRPWI 221 >3TK9-A nrPDB Length = 226 Score = 160 bits (405), Expect = 5e-40, Method: Compositional matrix adjust. Identities = 97/234 (41%), Positives = 129/234 (55%), Gaps = 13/234 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSL---DRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSI 85 IIGG+E PHSRPYM + + C G L+ KD+VLTAAHC V LGAH+I Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQ-GSSINVTLGAHNI 59 Query: 86 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 +E T+Q + VK+ P+P Y+P ++ LLQL KAK V L LP VKPG Sbjct: 60 KEQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQVKPG 119 Query: 146 TMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 205 +C VAGWG S + + TL+EV +T+ C H N++ +C G + + Sbjct: 120 QLCSVAGWGYVSMS-TLATTLQEVLLTVQKDCQCERLFHGNYSRA---TEICVGDPKKTQ 175 Query: 206 DSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 GDSG PL+C+ V +G+ S+G NK G P PGVYI +S L WI T+K Sbjct: 176 TGFKGDSGGPLVCKDVAQGILSYG--NKKGTP--PGVYIKVS-HFLPWIKRTMK 224 >3G01-A nrPDB Length = 227 Score = 159 bits (403), Expect = 8e-40, Method: Compositional matrix adjust. Identities = 92/236 (38%), Positives = 130/236 (55%), Gaps = 15/236 (6%) Query: 29 IIGGNEVTPHSRPYMVLLSL----DRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHS 84 IIGGNE++PHSRPYM +K C G L+ +VLTAAHC + V LGAH+ Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHCK-GRSMTVTLGAHN 59 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKP 144 I +E T+QI+ V K P+P Y+P R D+ LL+L+ AK + V L+LP++ VKP Sbjct: 60 IKAKEETQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNAHVKP 119 Query: 145 GTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 204 G C VAGWG+ + TL EV +T+ +VC + ++N N +C G + Sbjct: 120 GDECYVAGWGKVTPDGEFPKTLHEVKLTVQKDQVCESQFQSSYNRA---NEICVGDSKIK 176 Query: 205 RDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYI-LLSKKHLNWIIMTIK 259 S GDSG PL+C+ G+ S+G D P V+ +LS ++WI T+K Sbjct: 177 GASFRGDSGGPLVCKRAAAGIVSYGQT----DGSAPQVFTRVLS--FVSWIKKTMK 226 >3RP2-A nrPDB Length = 224 Score = 156 bits (394), Expect = 9e-39, Method: Compositional matrix adjust. Identities = 90/230 (39%), Positives = 126/230 (54%), Gaps = 15/230 (6%) Query: 29 IIGGNEVTPHSRPYMVLLSL----DRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHS 84 IIGG E PHSRPYM L + + IC G LI++ +VLTAAHC + VILGAH Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCK-GREITVILGAHD 59 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKP 144 + + E T+Q + V+K+ + Y+ D+ LL+L +K ++ V ++ LP D + P Sbjct: 60 VRKRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDFIHP 119 Query: 145 GTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 204 G MC AGWG+T S TLREV + I+D K C D +Y + VC GS Sbjct: 120 GAMCWAAGWGKTGVRDPTSYTLREVELRIMDEKACVDYRYYEYK-----FQVCVGSPTTL 174 Query: 205 RDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 R + GDSG PLLC GV G+ S+G D + P ++ +S ++ WI Sbjct: 175 RAAFMGDSGGPLLCAGVAHGIVSYGHP----DAKPPAIFTRVS-TYVPWI 219 >1UTJ-A nrPDB Length = 242 Score = 150 bits (379), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 85/230 (36%), Positives = 131/230 (56%), Gaps = 12/230 (5%) Query: 14 VVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLN 73 +++ ED +KI+GG E P+S+P+ V L+ C G+L+ ++WV++AAHC Sbjct: 8 LLIGAAFATED--DKIVGGYECKPYSQPHQVSLNSGYH-FCGGSLVNENWVVSAAHC-YK 63 Query: 74 KRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTIL 133 R +V LG H+I E ++Q + + +P Y + D+ L++L + A +N YV + Sbjct: 64 SRVEVRLGEHNIKVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPATLNTYVQPV 123 Query: 134 HLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGM 193 LP GTMC V+GWG T +S + S+ L+ +NI I+ CN+ ++ +I Sbjct: 124 ALPTSC--APAGTMCTVSGWGNTMSSTADSNKLQCLNIPILSYSDCNN----SYPGMITN 177 Query: 194 NMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVY 243 M CAG L GG+DSC GDSG P++C G +GV S+G C +P PGVY Sbjct: 178 AMFCAGYLEGGKDSCQGDSGGPVVCNGELQGVVSWGY--GCAEPGNPGVY 225 >2RDL-A nrPDB Length = 226 Score = 149 bits (377), Expect = 8e-37, Method: Compositional matrix adjust. Identities = 86/230 (37%), Positives = 131/230 (56%), Gaps = 15/230 (6%) Query: 29 IIGGNEVTPHSRPYMVLLSL----DRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHS 84 IIGG E PH+RPYM L + + + C+G LI +++V+TAAHC + V+LGAH+ Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHC-AGRSITVLLGAHN 59 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKP 144 +E T Q + V+K+FP+P YD D+ LL+L EKA + V L + K + + P Sbjct: 60 KKVKEDTWQKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPISAKSNSIPP 119 Query: 145 GTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 204 G +C+ GWGRT+ + SDTL+EV + I+D + C ++ P +C G+ + Sbjct: 120 GRVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQACKHFEDFHQEP-----QLCVGNPKKI 174 Query: 205 RDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 R+ GDSG PLLC G+ +G+ S+ L N + P V+ +S + WI Sbjct: 175 RNVYKGDSGGPLLCAGIAQGIASYVLRNA----KPPSVFTRIS-HYRPWI 219 >5MS3-A nrPDB Length = 228 Score = 147 bits (372), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 88/234 (37%), Positives = 131/234 (55%), Gaps = 14/234 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 ++GG+E PHS+P+ L ++ +C G L+ +WVLTAAHC K + V LG HS+ + Sbjct: 1 VLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYT-VRLGDHSLQNK 59 Query: 89 EPTKQIMLVKKEFPYPCYDPATREG---DLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 + +Q + V + P+PCY+ + E DL LLQL ++A + V + L +PG Sbjct: 60 DGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHC--TQPG 117 Query: 146 TMCQVAGWGR-THNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 204 C V+GWG T ++ DTL + I +K C D + I MVCAGS +G Sbjct: 118 QKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDA----YPGQITDGMVCAGSSKGA 173 Query: 205 RDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 D+C GDSG PL+C+G +G+TS+G + CG PGVY + ++L+WI I Sbjct: 174 -DTCQGDSGGPLVCDGALQGITSWG-SDPCGRSDKPGVYTNIC-RYLDWIKKII 224 >1KYN-A nrPDB Length = 235 Score = 142 bits (357), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 91/237 (38%), Positives = 133/237 (56%), Gaps = 20/237 (8%) Query: 29 IIGGNEVTPHSRPYMVLLSLDR---KTICAGALIAKDWVLTAAHC---NLNKRSQVILGA 82 IIGG E PHSRPYM L + ++ C G L+ +D+VLTAAHC N+N V LGA Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNIN----VTLGA 56 Query: 83 HSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDV 142 H+I R E T+Q + ++ +P Y+ T + D+ LLQL + + N+ V + LP+ + + Sbjct: 57 HNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGL 116 Query: 143 KPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 202 +PGT+C VAGWGR + +DTLREV + + + C R +++P +C G R Sbjct: 117 RPGTLCTVAGWGRV-SMRRGTDTLREVQLRVQRDRQC-LRIFGSYDP---RRQICVGDRR 171 Query: 203 GGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 + + GDSG PLLC V G+ S+G G P P V+ +S L WI T++ Sbjct: 172 ERKAAFKGDSGGPLLCNNVAHGIVSYG--KSSGVP--PEVFTRVS-SFLPWIRTTMR 223 >2ZKS-A nrPDB Length = 240 Score = 141 bits (356), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 88/231 (38%), Positives = 122/231 (52%), Gaps = 12/231 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQV--ILGAHSIT 86 IIGG EV PHSRPYM L + +C G L+ WVLTAAHC + +Q+ +LG H++ Sbjct: 1 IIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLGLHTLD 60 Query: 87 REEPTKQIMLVKKEFPYPCYDPA-TREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 T I K +P Y P E DL LLQL K K ++ + L LP K V G Sbjct: 61 SPGLTFHI---KAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQVVAAG 117 Query: 146 TMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 205 T C +AGWG TH S LRE+++ ++D ++CN+ +N + + +MVC + + Sbjct: 118 TRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGS--LSPSMVCLAADSKDQ 175 Query: 206 DSCNGDSGSPLLCEG--VFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 C GDSG PL+C V GV SF C D P V ++ +++WI Sbjct: 176 APCKGDSGGPLVCGKGRVLAGVLSFS-SRVCTDIFKPPVATAVA-PYVSWI 224 >1A0J-A nrPDB Length = 223 Score = 141 bits (355), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 85/232 (36%), Positives = 122/232 (52%), Gaps = 12/232 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 I+GG E +S Y L C G+LI+ WV++AAHC R QV LG H+I Sbjct: 1 IVGGYECRKNSASYQASLQSGYH-FCGGSLISSTWVVSAAHC-YKSRIQVRLGEHNIAVN 58 Query: 89 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMC 148 E T+Q + K +P Y+ + D+ L++L + A +N YV+ + LP GT C Sbjct: 59 EGTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALPSS--CASSGTRC 116 Query: 149 QVAGWGRTHNSAS-WSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDS 207 V+GWG S+S + DTLR +++ I+ CN + I NM CAG + GG+DS Sbjct: 117 LVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSA----YPGQITSNMFCAGFMEGGKDS 172 Query: 208 CNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 C GDSG P++C G +GV S+G C PGVY + + +WI T+ Sbjct: 173 CQGDSGGPVVCNGQLQGVVSWGY--GCAQRNKPGVYTKVC-NYRSWISSTMS 221 >3QUM-P nrPDB Length = 237 Score = 140 bits (353), Expect = 6e-34, Method: Compositional matrix adjust. Identities = 88/242 (36%), Positives = 128/242 (52%), Gaps = 21/242 (8%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 I+GG E HS+P+ VL++ + +C G L+ WVLTAAHC NK S ++LG HS+ Sbjct: 1 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNK-SVILLGRHSLFHP 59 Query: 89 EPTKQIMLVKKEFPYPCYDPAT------REGD-----LKLLQLMEKAKINKYVTILHLPK 137 E T Q+ V FP+P YD + R GD L LL+L E A++ V ++ LP Sbjct: 60 EDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPT 119 Query: 138 KGDDVKPGTMCQVAGWGRTHNSASWS-DTLREVNITIIDRKVCNDRNHYNFNPVIGMNMV 196 + + GT C +GWG + L+ V++ +I VC + + M+ Sbjct: 120 QEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK----VTKFML 173 Query: 197 CAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIM 256 CAG GG+ +C+GDSG PL+C GV +G+TS+G E C P P +Y + + WI Sbjct: 174 CAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSE-PCALPERPSLYTKVV-HYRKWIKD 231 Query: 257 TI 258 TI Sbjct: 232 TI 233 >2EEK-A nrPDB Length = 220 Score = 140 bits (352), Expect = 8e-34, Method: Compositional matrix adjust. Identities = 80/215 (37%), Positives = 120/215 (55%), Gaps = 10/215 (4%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 I+GG E T HS+ + V L+ C G+L++KDWV++AAHC +V LG H I Sbjct: 1 IVGGYECTKHSQAHQVSLNSGYH-FCGGSLVSKDWVVSAAHC-YKSVLRVRLGEHHIRVN 58 Query: 89 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMC 148 E T+Q + +P Y D+ L++L + A +N+YV + LP + TMC Sbjct: 59 EGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPT--ECAADATMC 116 Query: 149 QVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSC 208 V+GWG T +S + D L+ +++ I+ C + ++ +I +M CAG L GG+DSC Sbjct: 117 TVSGWGNTMSSVADGDKLQCLSLPILSHADCAN----SYPGMITQSMFCAGYLEGGKDSC 172 Query: 209 NGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVY 243 GDSG P++C GV +GV S+G C + PGVY Sbjct: 173 QGDSGGPVVCNGVLQGVVSWGY--GCAERDHPGVY 205 >1TON-A nrPDB Length = 235 Score = 137 bits (346), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 89/243 (36%), Positives = 131/243 (53%), Gaps = 23/243 (9%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 I+GG + +S+P+ V ++ + +C G LI WV+TAAHC N QV+LG +++ ++ Sbjct: 1 IVGGYKCEKNSQPWQV--AVINEYLCGGVLIDPSWVITAAHCYSNNY-QVLLGRNNLFKD 57 Query: 89 EPTKQIMLVKKEFPYPCYDP-----------ATREGDLKLLQLMEKAKINKYVTILHLPK 137 EP Q LV++ F +P Y P DL LL L E A I V ++ LP Sbjct: 58 EPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVIDLPT 117 Query: 138 KGDDVKPGTMCQVAGWGRTHNSASW-SDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMV 196 K + K G+ C +GWG T+ S S L+ VNI ++ + C + N V M+ Sbjct: 118 K--EPKVGSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTDV----ML 171 Query: 197 CAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIM 256 CAG + GG+D+C GDSG PL+C+GV +G+TS G C P+ P +Y L K +WI Sbjct: 172 CAGEMEGGKDTCAGDSGGPLICDGVLQGITSGG-ATPCAKPKTPAIYAKLI-KFTSWIKK 229 Query: 257 TIK 259 +K Sbjct: 230 VMK 232 >1AO5-A nrPDB Length = 237 Score = 137 bits (344), Expect = 6e-33, Method: Compositional matrix adjust. Identities = 86/242 (35%), Positives = 131/242 (54%), Gaps = 21/242 (8%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 ++GG +S+P+ V + ++ IC G L+ ++WVLTAAHC +++ +V LG + + +E Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQY-EVWLGKNKLFQE 59 Query: 89 EPTKQIMLVKKEFPYPCYD-----------PATREGDLKLLQLMEKAKINKYVTILHLPK 137 EP+ Q LV K FP+P ++ A DL LL+L + A I V + LP Sbjct: 60 EPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPIALPT 119 Query: 138 KGDDVKPGTMCQVAGWGR-THNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMV 196 K + KPG+ C +GWG T D L+ V IT++ + C V M+ Sbjct: 120 K--EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDV----ML 173 Query: 197 CAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIM 256 CAG + GG+D+C DSG PL+C+G+ +G TS+G CG P P +Y L K + +WI Sbjct: 174 CAGEMGGGKDTCRDDSGGPLICDGILQGTTSYG-PVPCGKPGVPAIYTNLIKFN-SWIKD 231 Query: 257 TI 258 T+ Sbjct: 232 TM 233 >4Q7Y-A nrPDB Length = 250 Score = 136 bits (343), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 85/237 (35%), Positives = 125/237 (52%), Gaps = 13/237 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQ---VILGAHSI 85 IIGG+EVTPHSRPYM + + C G L+ WV++AAHC ++ + V+LGAH + Sbjct: 1 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 60 Query: 86 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLP-KKGDDVKP 144 + EPT+Q+ + +P Y P T D+ LL+L A + V +L LP ++ Sbjct: 61 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRARPPTA 120 Query: 145 GTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 204 GT C+VAGWG + L E + ++D VCN ++ + + M+C S Sbjct: 121 GTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNS----SWKGHLTLTMLCTRSGDSH 176 Query: 205 RDS-CNGDSGSPLLCEGVFRGVTSF-GLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 R C+ DSG PL+C G+ SF GL CGDP+ P VY +S + WI ++ Sbjct: 177 RRGFCSADSGGPLVCRNRAHGLVSFSGLW--CGDPKTPDVYTQVS-AFVAWIWDVVR 230 >4AN7-A nrPDB Length = 231 Score = 136 bits (343), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 83/239 (34%), Positives = 124/239 (51%), Gaps = 12/239 (5%) Query: 21 IPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVIL 80 P D +KI+GG +S PY V L+ C G+LI WV++AAHC R QV L Sbjct: 1 FPTDDDDKIVGGYTCAANSIPYQVSLN-SGSHFCGGSLINSQWVVSAAHC-YKSRIQVRL 58 Query: 81 GAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGD 140 G H+I E +Q + K +P ++ T + D+ L++L A +N V + LP+ Sbjct: 59 GEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSC- 117 Query: 141 DVKPGTMCQVAGWGRTHNS-ASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAG 199 GT C ++GWG T +S +S+ L+ + ++ C ++ I NM+C G Sbjct: 118 -AAAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKS----SYPGQITGNMICVG 172 Query: 200 SLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 L GG+DSC GDSG P++C G +G+ S+G C PGVY + ++NWI TI Sbjct: 173 FLEGGKDSCQGDSGGPVVCNGQLQGIVSWGY--GCAQKNKPGVYTKVC-NYVNWIQQTI 228 >5FXL-A nrPDB Length = 246 Score = 136 bits (342), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 84/248 (33%), Positives = 126/248 (50%), Gaps = 12/248 (4%) Query: 12 LSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCN 71 L+++ + + P D +KI+GG ++ PY V L+ C G+LI WV++AAHC Sbjct: 7 LALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYH-FCGGSLINSQWVVSAAHC- 64 Query: 72 LNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVT 131 QV LG +I E +Q + K +P Y+ T D+ L++L A +N V Sbjct: 65 YKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVA 124 Query: 132 ILHLPKKGDDVKPGTMCQVAGWGRTHNSA-SWSDTLREVNITIIDRKVCNDRNHYNFNPV 190 + LP GT C ++GWG T +S S+ D L+ + I+ C + Sbjct: 125 SISLPTSC--ASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSA----YPGQ 178 Query: 191 IGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKH 250 I NM CAG L GG+DSC GDSG P++C G +G+ S+G + C PGVY + + Sbjct: 179 ITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWG--SGCAQKNKPGVYTKVC-NY 235 Query: 251 LNWIIMTI 258 ++WI TI Sbjct: 236 VSWIKQTI 243 >4NFE-A nrPDB Length = 237 Score = 136 bits (342), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 89/242 (36%), Positives = 122/242 (50%), Gaps = 21/242 (8%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 I+GG E HS+P+ V + C G L+ WVLTAAHC L K SQV LG H++ Sbjct: 1 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHC-LKKNSQVWLGRHNLFEP 59 Query: 89 EPTKQIMLVKKEFPYPCYDPA-----------TREGDLKLLQLMEKAKINKYVTILHLPK 137 E T Q + V FP+P Y+ + DL LL+L E AKI V +L LP Sbjct: 60 EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 119 Query: 138 KGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIID-RKVCNDRNHYNFNPVIGMNMV 196 + + GT C +GWG + LR ++ + + ND ++ + M+ Sbjct: 120 QEPAL--GTTCYASGWGSIEPE----EFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFML 173 Query: 197 CAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIM 256 CAG GG+D+C GDSG PL+C GV +G+TS+G E C P P VY + + WI Sbjct: 174 CAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPE-PCALPEKPAVYTKVV-HYRKWIKD 231 Query: 257 TI 258 TI Sbjct: 232 TI 233 >1SGF-G nrPDB Length = 237 Score = 134 bits (336), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 83/242 (34%), Positives = 133/242 (54%), Gaps = 21/242 (8%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 I+GG + +S+P+ V + + +C G L+ +WVLTAAHC + +V LG +++ ++ Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQYLCGGVLLDPNWVLTAAHC-YDDNYKVWLGKNNLFKD 59 Query: 89 EPTKQIMLVKKEFPYPCYDPA-----------TREGDLKLLQLMEKAKINKYVTILHLPK 137 EP+ Q V K P+P ++ + DL LL+L + A I V + LP Sbjct: 60 EPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPITLPT 119 Query: 138 KGDDVKPGTMCQVAGWGR-THNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMV 196 ++ K G+ C +GWG T ++D L VN+ ++ + C + H + M+ Sbjct: 120 --EEPKLGSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCA-KAHIE---KVTDAML 173 Query: 197 CAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIM 256 CAG + GG+D+C GDSG PL+C+GV +G+TS+G CG+P PGVY L+ K +WI Sbjct: 174 CAGEMDGGKDTCKGDSGGPLICDGVLQGITSWG-HTPCGEPDMPGVYTKLN-KFTSWIKD 231 Query: 257 TI 258 T+ Sbjct: 232 TM 233 >3E0N-B nrPDB Length = 271 Score = 134 bits (336), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 78/240 (32%), Positives = 123/240 (51%), Gaps = 17/240 (7%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHC----NLNKRSQVILGAHS 84 I GG+ P+ V ++ + +C G+L+++ WVL+AAHC + + +V LGAH Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKP 144 + ++ +K P+P Y +GD+ LLQL ++Y+ + LP Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQASFPN 120 Query: 145 GTMCQVAGWGRTHNSASW--SDTLREVNITIIDRKVCNDRNHYNFNP----VIGMNMVCA 198 G C V GWG S S L+++ + +I R+ CN + + P + +MVCA Sbjct: 121 GLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQEDMVCA 180 Query: 199 GSLRGGRDSCNGDSGSPLLC--EGVF--RGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 G + GG+D+C GDSG PL C EG++ G+ S+G + CG PGVY L S + +WI Sbjct: 181 GYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWG--DACGARNRPGVYTLAS-SYASWI 237 >3DFJ-A nrPDB Length = 263 Score = 133 bits (335), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 78/240 (32%), Positives = 123/240 (51%), Gaps = 17/240 (7%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHC----NLNKRSQVILGAHS 84 I GG+ P+ V ++ + +C G+L+++ WVL+AAHC + + +V LGAH Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKP 144 + ++ +K P+P Y +GD+ LLQL ++Y+ + LP Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAANASFPN 120 Query: 145 GTMCQVAGWGRTHNSASW--SDTLREVNITIIDRKVCNDRNHYNFNP----VIGMNMVCA 198 G C V GWG S S L+++ + +I R+ CN + + P + +MVCA Sbjct: 121 GLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFVQEDMVCA 180 Query: 199 GSLRGGRDSCNGDSGSPLLC--EGVF--RGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 G + GG+D+C GDSG PL C EG++ G+ S+G + CG PGVY L S + +WI Sbjct: 181 GYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWG--DACGARNRPGVYTLAS-SYASWI 237 >1SPJ-A nrPDB Length = 238 Score = 132 bits (333), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 86/243 (35%), Positives = 129/243 (53%), Gaps = 22/243 (9%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 I+GG E HS+P+ L C G L+ + WVLTAAHC ++ Q+ LG H++ + Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHC-ISDNYQLWLGRHNLFDD 59 Query: 89 EPTKQIMLVKKEFPYPCYDPA-----TREGD------LKLLQLMEKAK-INKYVTILHLP 136 E T Q + V + FP+P ++ + TR+ D L LL+L E A I V ++ LP Sbjct: 60 ENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVELP 119 Query: 137 KKGDDVKPGTMCQVAGWGRTH-NSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNM 195 + +V G+ C +GWG + S+ D L+ V++ I+ C + M Sbjct: 120 TEEPEV--GSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDF----M 173 Query: 196 VCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWII 255 +C G L GG+D+C GDSG PL+C+GV +GVTS+G CG P P V + + ++ WI Sbjct: 174 LCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYV-PCGTPNKPSVAVRV-LSYVKWIE 231 Query: 256 MTI 258 TI Sbjct: 232 DTI 234 >1EKB-B nrPDB Length = 235 Score = 132 bits (332), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 75/237 (31%), Positives = 123/237 (51%), Gaps = 18/237 (7%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNK-----RSQVILGAH 83 I+GG++ + P++V L D + +C +L+++DW+++AAHC + + + +LG H Sbjct: 1 IVGGSDSREGAWPWVVALYFDDQQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVLGLH 60 Query: 84 SITR-EEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDV 142 + P + L+ + P Y+ + D+ ++ L K Y+ + LP++ Sbjct: 61 MASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLPEENQVF 120 Query: 143 KPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDR-NHYNFNPVIGMNMVCAGSL 201 PG +C +AGWG S +D L+E ++ ++ + C + YN I NMVCAG Sbjct: 121 PPGRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQQMPEYN----ITENMVCAGYE 176 Query: 202 RGGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 GG DSC GDSG PL+C+ + GVTSFG + C P PGVY + + WI Sbjct: 177 AGGVDSCQGDSGGPLMCQENNRWLLAGVTSFGYQ--CALPNRPGVYARV-PRFTEWI 230 >1NPM-A nrPDB Length = 225 Score = 132 bits (332), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 82/234 (35%), Positives = 119/234 (50%), Gaps = 14/234 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 I+ G E PHS+P+ L + IC G L+ WVLTAAHC K S V LG HS+ Sbjct: 1 ILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAAHCKKQKYS-VRLGDHSLQSR 59 Query: 89 EPTKQIMLVKKEFPYPCY---DPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 + +Q + V + +PCY +P D+ L++L A + V + L V G Sbjct: 60 DQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQLANLCPKV--G 117 Query: 146 TMCQVAGWGR-THNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 204 C ++GWG T ++ +TL + I + C + I MVCAGS G Sbjct: 118 QKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKC----ERAYPGKITEGMVCAGSSNGA 173 Query: 205 RDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 D+C GDSG PL+C+G+ +G+TS+G + CG P PGVY + ++ WI T+ Sbjct: 174 -DTCQGDSGGPLVCDGMLQGITSWG-SDPCGKPEKPGVYTKIC-RYTTWIKKTM 224 >1F7Z-A nrPDB Length = 233 Score = 130 bits (328), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 84/239 (35%), Positives = 123/239 (51%), Gaps = 12/239 (5%) Query: 21 IPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVIL 80 P D + I+GG +S PY V L+ C G+LI WV++AAHC R QV L Sbjct: 3 FPVDDDDAIVGGYTCQENSVPYQVSLNSGYH-FCGGSLINDQWVVSAAHC-YKSRIQVRL 60 Query: 81 GAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGD 140 G H+I E +Q + K +P +D T D+ L++L K+N V + LP Sbjct: 61 GEHNINVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVALPSSC- 119 Query: 141 DVKPGTMCQVAGWGRTHNSA-SWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAG 199 GT C ++GWG T +S + D L+ ++ ++ + C ++ I NMVC G Sbjct: 120 -APAGTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADC----EASYPGKITDNMVCVG 174 Query: 200 SLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 L GG+DSC GDSG P++C G +G+ S+G C P PGVY + +++WI TI Sbjct: 175 FLEGGKDSCQGDSGGPVVCNGELQGIVSWGY--GCALPDNPGVYTKVC-NYVDWIQDTI 230 >4WWY-A nrPDB Length = 224 Score = 130 bits (327), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 82/231 (35%), Positives = 121/231 (52%), Gaps = 12/231 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 I+GG +S PY V L+ C G+LI + WV++A HC R QV LG H+I Sbjct: 1 IVGGYNCEENSVPYQVSLNSGYH-FCGGSLINEQWVVSAGHC-YKSRIQVRLGEHNIEVL 58 Query: 89 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMC 148 E +Q + K +P YD T D+ L++L +A IN +V+ + LP GT C Sbjct: 59 EGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLPTA--PPATGTKC 116 Query: 149 QVAGWGRTHNS-ASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDS 207 ++GWG T +S A + D L+ ++ ++ + C ++ I NM C G L GG+DS Sbjct: 117 LISGWGNTASSGADYPDELQCLDAPVLSQAKC----EASYPGKITSNMFCVGFLEGGKDS 172 Query: 208 CNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 C DSG P++C G +GV S+G + C PGVY + ++ WI TI Sbjct: 173 CQRDSGGPVVCNGQLQGVVSWG--DGCAQKNKPGVYTKV-YNYVKWIKNTI 220 >5UGG-A nrPDB Length = 251 Score = 129 bits (325), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 94/244 (38%), Positives = 125/244 (51%), Gaps = 25/244 (10%) Query: 22 PEDVCEKIIGGNEVTPHSRPYMVLLSLDRKT-ICAGALIAKDWVLTAAHCNLNKRS---- 76 P+ +++GG PHS P+ V L C G LI+ +WVLTAAHC L K Sbjct: 15 PKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHC-LEKSPRPSS 73 Query: 77 -QVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHL 135 +VILGAH EP Q + V + F P TR+ D+ LL+L A I V L Sbjct: 74 YKVILGAHQEVNLEPHVQEIEVSRLFLEP-----TRK-DIALLKLSSPAVITDKVIPACL 127 Query: 136 PKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNF-NPVIGMN 194 P V T C + GWG T + + L+E + +I+ KVCN Y F N + Sbjct: 128 PSPNYVVADRTECFITGWGETQGTFG-AGLLKEAQLPVIENKVCN---RYEFLNGRVQST 183 Query: 195 MVCAGSLRGGRDSCNGDSGSPLLC----EGVFRGVTSFGLENKCGDPRGPGVYILLSKKH 250 +CAG L GG DSC GDSG PL+C + + +GVTS+GL C P PGVY+ +S + Sbjct: 184 ELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGL--GCARPNKPGVYVRVS-RF 240 Query: 251 LNWI 254 + WI Sbjct: 241 VTWI 244 >4DGJ-A nrPDB Length = 235 Score = 129 bits (324), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 79/237 (33%), Positives = 122/237 (51%), Gaps = 18/237 (7%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHC----NLN-KRSQVILGAH 83 I+GG++ + P++V L D + +C +L++ DW+++AAHC NL + ILG H Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLH 60 Query: 84 SITR-EEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDV 142 + P L+ + P Y+ ++ D+ ++ L K Y+ + LP++ Sbjct: 61 MKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPEENQVF 120 Query: 143 KPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDR-NHYNFNPVIGMNMVCAGSL 201 PG C +AGWG + +D L+E ++ ++ + C + YN I NM+CAG Sbjct: 121 PPGRNCSIAGWGTVVYQGTTADILQEADVPLLSNERCQQQMPEYN----ITENMICAGYE 176 Query: 202 RGGRDSCNGDSGSPLLCEGVFR----GVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 GG DSC GDSG PL+C+ R GVTSFG E C P PGVY +S + WI Sbjct: 177 EGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYE--CALPNRPGVYARVS-RFTEWI 230 >1PPF-E nrPDB Length = 218 Score = 127 bits (320), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 80/236 (33%), Positives = 121/236 (51%), Gaps = 23/236 (9%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVI---LGAHSI 85 I+GG PH+ P+MV L L C LIA ++V++AAHC N + + LGAH++ Sbjct: 1 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 60 Query: 86 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 +R EPT+Q+ V++ F YDP D+ +LQL A IN V + LP +G + G Sbjct: 61 SRREPTRQVFAVQRIFENG-YDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 119 Query: 146 TMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 205 C GWG + + L+E+N+T++ +C N VC +L GR Sbjct: 120 VQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRSN------------VC--TLVRGR 164 Query: 206 DS--CNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 + C GDSGSPL+C G+ G+ SF + C P + ++ + +NWI I+ Sbjct: 165 QAGVCFGDSGSPLVCNGLIHGIASF-VRGGCASGLYPDAFAPVA-QFVNWIDSIIQ 218 >4DUR-A nrPDB Length = 791 Score = 127 bits (318), Expect = 6e-30, Method: Compositional matrix adjust. Identities = 93/238 (39%), Positives = 123/238 (51%), Gaps = 25/238 (10%) Query: 28 KIIGGNEVTPHSRPYMVLLSLDRKT-ICAGALIAKDWVLTAAHCNLNKRS-----QVILG 81 +++GG PHS P+ V L C G LI+ +WVLTAAHC L K +VILG Sbjct: 561 RVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHC-LEKSPRPSSYKVILG 619 Query: 82 AHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDD 141 AH EP Q + V + F P TR+ D+ LL+L A I V LP Sbjct: 620 AHQEVNLEPHVQEIEVSRLFLEP-----TRK-DIALLKLSSPAVITDKVIPACLPSPNYV 673 Query: 142 VKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNF-NPVIGMNMVCAGS 200 V T C + GWG T + + L+E + +I+ KVCN Y F N + +CAG Sbjct: 674 VADRTECFITGWGETQGTFG-AGLLKEAQLPVIENKVCN---RYEFLNGRVQSTELCAGH 729 Query: 201 LRGGRDSCNGDSGSPLLC----EGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 L GG DSC GDSG PL+C + + +GVTS+GL C P PGVY+ +S + + WI Sbjct: 730 LAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGL--GCARPNKPGVYVRVS-RFVTWI 784 >1SGF-A nrPDB Length = 240 Score = 127 bits (318), Expect = 7e-30, Method: Compositional matrix adjust. Identities = 81/233 (34%), Positives = 125/233 (53%), Gaps = 21/233 (9%) Query: 38 HSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLV 97 +S+P+ V + K C G L+ ++WVLTAAHC N + QV LG ++ +EP+ Q LV Sbjct: 13 NSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHC-YNDKYQVWLGKNNFLEDEPSDQHRLV 71 Query: 98 KKEFPYPCYD--------PATRE---GDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGT 146 K P+P ++ P + DL LL+L + A I V + LP ++ K G+ Sbjct: 72 SKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPT--EEPKLGS 129 Query: 147 MCQVAGWGRTHN-SASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 205 C +GWG T + D L+ VN+ ++ + C+ + + M+CAG + GG Sbjct: 130 TCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMK----VTDAMLCAGEMDGGS 185 Query: 206 DSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 +C DSG PL+C+G+ +G+TS+G E CG+P P VY L K +WI T+ Sbjct: 186 YTCEHDSGGPLICDGILQGITSWGPE-PCGEPTEPSVYTKLI-KFSSWIRETM 236 >1AE5-A nrPDB Length = 225 Score = 127 bits (318), Expect = 7e-30, Method: Compositional matrix adjust. Identities = 84/231 (36%), Positives = 112/231 (48%), Gaps = 23/231 (9%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKR---SQVILGAHSI 85 I+GG + P P++ + + C GALI +V+TAA C ++ S V+LGA+ + Sbjct: 1 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 60 Query: 86 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 R E + YDP DL LLQL +A + VTIL LP + V+ G Sbjct: 61 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 120 Query: 146 TMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSL--RG 203 T CQVAGWG + S R VN+T+ C N VC G L RG Sbjct: 121 TRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNN------------VCTGVLTRRG 168 Query: 204 GRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 G CNGD G+PL+CEG+ GV SF L CG RGP + ++ +WI Sbjct: 169 G--ICNGDGGTPLVCEGLAHGVASFSL-GPCG--RGPDFFTRVA-LFRDWI 213 >6QHB-A nrPDB Length = 223 Score = 126 bits (316), Expect = 9e-30, Method: Compositional matrix adjust. Identities = 80/231 (34%), Positives = 122/231 (52%), Gaps = 10/231 (4%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 ++ G S PY L +C G LI WVLTAAHC QV LG H++ ++ Sbjct: 1 LVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCK-KPNLQVFLGKHNLGQQ 59 Query: 89 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMC 148 E +++ V + +P YD A+ + D+ LL+L AK+++ + L P + D T C Sbjct: 60 ESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPL--PLERDCSAQTTSC 117 Query: 149 QVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSC 208 + GWG+T + + DT++ I ++ R+ C + + I NM+CAG + G+DSC Sbjct: 118 HILGWGKTAD-GDFPDTIQCAYIHLVSREECE----HAYPGQITQNMLCAGDEKYGKDSC 172 Query: 209 NGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 GDSG PL+C RG+ S+G CG PGVY + ++ NWI TI+ Sbjct: 173 QGDSGGPLVCGDHLRGLVSWG-NIPCGSKEKPGVYTNVC-RYTNWIQKTIQ 221 >1FUJ-A nrPDB Length = 221 Score = 124 bits (310), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 79/237 (33%), Positives = 120/237 (50%), Gaps = 22/237 (9%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKT---ICAGALIAKDWVLTAAHC--NLNKR-SQVILGA 82 I+GG+E PHSRPYM L + C G LI +VLTAAHC ++ +R V+LGA Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 60 Query: 83 HSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDV 142 H++ +EPT+Q V + F YD + D+ L+QL A ++ V + LP++ V Sbjct: 61 HNVRTQEPTQQHFSVAQVF-LNNYDAENKLNDILLIQLSSPANLSASVATVQLPQQDQPV 119 Query: 143 KPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 202 GT C GWGR + L+E+N+T++ C N F P R Sbjct: 120 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT-FFCRPHNICTFVP------------R 166 Query: 203 GGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 C GDSG PL+C+G+ +G+ SF + C P + ++ +++WI T++ Sbjct: 167 RKAGICFGDSGGPLICDGIIQGIDSFVIWG-CATRLFPDFFTRVA-LYVDWIRSTLR 221 >3W94-A nrPDB Length = 235 Score = 123 bits (309), Expect = 8e-29, Method: Compositional matrix adjust. Identities = 79/240 (32%), Positives = 116/240 (48%), Gaps = 18/240 (7%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQV-----ILGAH 83 ++GG + P+MV L + C +LI +DW+LTAAHC K + + +LG H Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRGRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVLGLH 60 Query: 84 SITREEPTK-QIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDV 142 + + + QI V + Y+ T+E D+ ++ L + ++V + L + Sbjct: 61 AQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLASEDQHF 120 Query: 143 KPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCND-RNHYNFNPVIGMNMVCAGSL 201 G C +AGWGR S D L+E + ++D+ C Y F +M+CAG Sbjct: 121 PAGRRCFIAGWGRDAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTS----SMLCAGYP 176 Query: 202 RGGRDSCNGDSGSPLLCEGVFR----GVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMT 257 GG DSC GDSG PL+C R GVTSFG+ CG P PG Y +S +WI T Sbjct: 177 EGGVDSCQGDSGGPLMCLEDARWTLIGVTSFGV--GCGRPERPGAYARVS-AFTSWIAET 233 >5ZFH-A nrPDB Length = 224 Score = 123 bits (308), Expect = 9e-29, Method: Compositional matrix adjust. Identities = 78/232 (33%), Positives = 120/232 (51%), Gaps = 12/232 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 II G + S P+ V L + C G L+ K WVLTAAHC + + QV LG+ I + Sbjct: 1 IIDGYKCKEGSHPWQVALLKGNQLHCGGVLVDKYWVLTAAHCKMGQY-QVQLGSDKIGDQ 59 Query: 89 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMC 148 + Q + K F +P Y T D+ L++L E K++ V + LP+ + PGT C Sbjct: 60 --SAQKIKATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLPEHCE--PPGTSC 115 Query: 149 QVAGWGRTHN-SASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDS 207 V+GWG T + ++ L ++ +I + C + ++G M+CAG ++ Sbjct: 116 TVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKV----YKDLLGKTMLCAGIPDSKTNT 171 Query: 208 CNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 CNGDSG PL+C +G+ S+G CG P PGVY + K+ W++ T+K Sbjct: 172 CNGDSGGPLVCNDTLQGLVSWGT-YPCGQPNDPGVYTQVC-KYKRWVMETMK 221 >5C67-A nrPDB Length = 224 Score = 121 bits (303), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 79/231 (34%), Positives = 122/231 (52%), Gaps = 12/231 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 I+GG +S PY V L+ C G+LI++ WV++AAHC R QV LG H+I Sbjct: 1 IVGGYTCEENSLPYQVSLN-SGSHFCGGSLISEQWVVSAAHC-YKTRIQVRLGEHNIKVL 58 Query: 89 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMC 148 E +Q + K +P Y+ T + D+ L++L A IN V+ + LP GT C Sbjct: 59 EGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTA--PPAAGTEC 116 Query: 149 QVAGWGRTHN-SASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDS 207 ++GWG T + A + D L+ ++ ++ + C ++ I +M C G L GG+DS Sbjct: 117 LISGWGNTLSFGADYPDELKCLDAPVLTQAECKA----SYPGKITNSMFCVGFLEGGKDS 172 Query: 208 CNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 C D+G P++C G +GV S+G + C PGVY + +++WI TI Sbjct: 173 CQRDAGGPVVCNGQLQGVVSWG--HGCAWKNRPGVYTKV-YNYVDWIKDTI 220 >3BSQ-A nrPDB Length = 227 Score = 121 bits (303), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 78/232 (33%), Positives = 121/232 (52%), Gaps = 12/232 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 II G S P+ V L + C G L+ + WVLTAAHC +N+ + V LG+ ++ Sbjct: 1 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYT-VHLGSDTLGDR 59 Query: 89 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMC 148 Q + K F +P Y T DL L++L +A+++ V + LP + + PGT C Sbjct: 60 R--AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPGTTC 115 Query: 149 QVAGWGRTHN-SASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDS 207 V+GWG T + ++ L V++ +I + C + ++ +M+CAG +++ Sbjct: 116 TVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKV----YKDLLENSMLCAGIPDSKKNA 171 Query: 208 CNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 CNGDSG PL+C G +G+ S+G CG P PGVY + K WI T+K Sbjct: 172 CNGDSGGPLVCRGTLQGLVSWG-TFPCGQPNDPGVYTQVC-KFTKWINDTMK 221 >1BQY-A nrPDB Length = 234 Score = 120 bits (302), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 81/234 (34%), Positives = 126/234 (53%), Gaps = 10/234 (4%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 + GG+E + +V+L +C G LI +DWV+TAAHC+ N Q++ G HS Sbjct: 1 VFGGDECNINEHRSLVVLFNSNGFLCGGTLINQDWVVTAAHCDSNNF-QLLFGVHSKKIL 59 Query: 89 EPTKQIMLVKKEFPYPCYDPATR-EGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTM 147 +Q K++F P + D+ L++L ++++ L LP V G++ Sbjct: 60 NEDEQTRDPKEKFFCPNRKKDDEVDKDIMLIKLDSSVSNSEHIAPLSLPSSPPSV--GSV 117 Query: 148 CQVAGWGRTHNSAS-WSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRD 206 C++ GWG+T + + D NI I+D VC R Y++ V + CAG L+GGRD Sbjct: 118 CRIMGWGKTIPTKEIYPDVPHCANINILDHAVC--RTAYSWRQVANTTL-CAGILQGGRD 174 Query: 207 SCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 +C+ DSG PL+C G+F+G+ S+G + CG P PGVY + +L+WI I G Sbjct: 175 TCHFDSGGPLICNGIFQGIVSWG-GHPCGQPGEPGVYTKVF-DYLDWIKSIIAG 226 >1ELT-A nrPDB Length = 236 Score = 120 bits (301), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 74/237 (31%), Positives = 119/237 (50%), Gaps = 16/237 (6%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKT----ICAGALIAKDWVLTAAHCNLNKRS-QVILGAH 83 ++GG P+S P+ + L + C G+LI + WV+TAAHC + R+ +V+LG H Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSARTWRVVLGEH 60 Query: 84 SITREEPTKQIMLVKKEFPYPCYDPATREG--DLKLLQLMEKAKINKYVTILHLPKKGDD 141 ++ E +QIM V F + ++ G D+ LL+L +A +N V + LP Sbjct: 61 NLNTNEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPSNQI 120 Query: 142 VKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSL 201 + C + GWG+T SD+L++ + +D C+ + + MVCAG Sbjct: 121 LPNNNPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSSSGWW--GSTVKTTMVCAGG- 177 Query: 202 RGGRDSCNGDSGSPLLCE--GVF--RGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 G CNGDSG PL C+ G + GVTSF + C + P V+ +S +++W+ Sbjct: 178 -GANSGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVS-AYISWM 232 >3T2N-A nrPDB Length = 372 Score = 120 bits (300), Expect = 8e-28, Method: Compositional matrix adjust. Identities = 79/251 (31%), Positives = 119/251 (47%), Gaps = 24/251 (9%) Query: 27 EKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVI----LGA 82 ++I+GG + + P+ V L D +C G+L++ DWVLTAAHC +R++V+ + A Sbjct: 116 DRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHC-FPERNRVLSRWRVFA 174 Query: 83 HSITREEPTKQIMLVKKEFPY----PCYDPATREG--DLKLLQLMEKAKINKYVTILHLP 136 ++ + P + V+ + P DP + E D+ L+ L + +Y+ + LP Sbjct: 175 GAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLP 234 Query: 137 KKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMV 196 G + G +C V GWG T + L+E + II VCN + Y I M Sbjct: 235 AAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQ--IKPKMF 292 Query: 197 CAGSLRGGRDSCNGDSGSPLLCEGVFR--------GVTSFGLENKCGDPRGPGVYILLSK 248 CAG GG D+C GDSG P +CE G+ S+G C + PGVY +S Sbjct: 293 CAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWG--TGCALAQKPGVYTKVSD 350 Query: 249 KHLNWIIMTIK 259 WI IK Sbjct: 351 FR-EWIFQAIK 360 >1YC0-A nrPDB Length = 283 Score = 119 bits (299), Expect = 9e-28, Method: Compositional matrix adjust. Identities = 79/243 (32%), Positives = 125/243 (51%), Gaps = 24/243 (9%) Query: 28 KIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQ----VILGAH 83 +IIGG+ P S P++ + + + CAG+L+ WV++AAHC + + V+LG H Sbjct: 35 RIIGGSSSLPGSHPWLAAIYIG-DSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQH 93 Query: 84 SITREEPTKQIMLVKKEFPYPCY---DPATREGDLKLLQLMEK----AKINKYVTILHLP 136 R Q ++K PY Y +P+ + DL L++L +K A +++V + LP Sbjct: 94 FFNRTTDVTQTFGIEKYIPYTLYSVFNPS--DHDLVLIRLKKKGDRCATRSQFVQPICLP 151 Query: 137 KKGDDVKPGTMCQVAGWGR-THNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNM 195 + G G CQ+AGWG N + +S +LRE + ++ C+ Y + I NM Sbjct: 152 EPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGAD--ISPNM 209 Query: 196 VCAGSLRGGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHL 251 +CAG D+C GDSG PL CE G+ S+G + CG PGVY ++ ++ Sbjct: 210 LCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWG--DGCGRLHKPGVYTRVA-NYV 266 Query: 252 NWI 254 +WI Sbjct: 267 DWI 269 >5TJX-A nrPDB Length = 263 Score = 119 bits (299), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 78/242 (32%), Positives = 125/242 (51%), Gaps = 23/242 (9%) Query: 28 KIIGGNEVTPHSRPYMVLLSLD---RKTICAGALIAKDWVLTAAHC-------NLNKRSQ 77 +I+GG E + P+ V L + ++ +C G+LI WVLTAAHC ++ + Sbjct: 15 RIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 74 Query: 78 VILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPK 137 IL IT++ P QI K+ + Y + D+ L++L + ++ + LP Sbjct: 75 GILELSDITKDTPFSQI---KEIIIHQNYKVSEGNHDIALIKLQAPLEYTEFQKPISLPS 131 Query: 138 KGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVC 197 KGD T C V GWG + + L++VNI ++ + C R + I MVC Sbjct: 132 KGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQ---DYKITQRMVC 188 Query: 198 AGSLRGGRDSCNGDSGSPLLCE--GVFR--GVTSFGLENKCGDPRGPGVYILLSKKHLNW 253 AG GG+D+C GDSG PL+C+ G++R G+TS+G C PGVY ++ ++++W Sbjct: 189 AGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG--EGCARREQPGVYTKVA-EYMDW 245 Query: 254 II 255 I+ Sbjct: 246 IL 247 >2R0L-A nrPDB Length = 248 Score = 119 bits (298), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 78/240 (32%), Positives = 121/240 (50%), Gaps = 20/240 (8%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQ----VILGAHS 84 IIGG+ P S P++ + + + CAG+L+ WV++AAHC + + V+LG H Sbjct: 1 IIGGSSSLPGSHPWLAAIYIG-DSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHF 59 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPAT-REGDLKLLQLMEK----AKINKYVTILHLPKKG 139 R Q ++K PY Y + DL L++L +K A +++V + LP+ G Sbjct: 60 FNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPG 119 Query: 140 DDVKPGTMCQVAGWGR-THNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCA 198 G CQ+AGWG N + +S +LRE + ++ C+ Y + I NM+CA Sbjct: 120 STFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGAD--ISPNMLCA 177 Query: 199 GSLRGGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 G D+C GDSG PL CE G+ S+G + CG PGVY ++ +++WI Sbjct: 178 GYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWG--DGCGRLHKPGVYTRVA-NYVDWI 234 >4E7N-A nrPDB Length = 238 Score = 119 bits (298), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 83/242 (34%), Positives = 126/242 (52%), Gaps = 22/242 (9%) Query: 29 IIGGNEVTPHSRPYMVLL--SLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSIT 86 IIGG+E + ++V L S R C G LI ++WVLTAAHC+ K ++ LG HS Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRTLFCGGTLINQEWVLTAAHCD-RKNFRIKLGMHSKK 59 Query: 87 REEPTKQIMLVKKEF------PYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGD 140 +Q + K++F Y +D D+ L++L K +K++ LP Sbjct: 60 VPNEDEQTRVPKEKFFCLSSKNYTLWD-----KDIMLIRLDSPVKNSKHIAPFSLPSSPP 114 Query: 141 DVKPGTMCQVAGWGR-THNSASWSDTLREVNITIIDRKVCNDRNHY-NFNPVIGMNMVCA 198 V G++C++ GWGR + ++ D VNI +++ ++C R Y F +CA Sbjct: 115 SV--GSVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMC--RAPYPEFELPATSRTLCA 170 Query: 199 GSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 G L GG+D+C GDSG PL+C G F+G+ S+G ++ C P P Y + HL+WI I Sbjct: 171 GILEGGKDTCKGDSGGPLICNGQFQGIASWG-DDPCAQPHKPAAYTKVF-DHLDWIENII 228 Query: 259 KG 260 G Sbjct: 229 AG 230 >1P57-B nrPDB Length = 255 Score = 118 bits (296), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 79/249 (31%), Positives = 117/249 (46%), Gaps = 24/249 (9%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVI----LGAHS 84 I+GG + + P+ V L D +C G+L++ DWVLTAAHC +R++V+ + A + Sbjct: 1 IVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHC-FPERNRVLSRWRVFAGA 59 Query: 85 ITREEPTKQIMLVKKEFPY----PCYDPATREG--DLKLLQLMEKAKINKYVTILHLPKK 138 + + P + V+ + P DP + E D+ L+ L + +Y+ + LP Sbjct: 60 VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAA 119 Query: 139 GDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCA 198 G + G +C V GWG T + L+E + II VCN + Y I M CA Sbjct: 120 GQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQ--IKPKMFCA 177 Query: 199 GSLRGGRDSCNGDSGSPLLCEGVFR--------GVTSFGLENKCGDPRGPGVYILLSKKH 250 G GG D+C GDSG P +CE G+ S+G C + PGVY +S Sbjct: 178 GYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWG--TGCALAQKPGVYTKVSDFR 235 Query: 251 LNWIIMTIK 259 WI IK Sbjct: 236 -EWIFQAIK 243 >2TLD-E nrPDB Length = 220 Score = 117 bits (294), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 80/231 (34%), Positives = 116/231 (50%), Gaps = 15/231 (6%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 I+GG ++ PY V L+ C G+LI WV++AAHC QV LG +I Sbjct: 1 IVGGYTCGANTVPYQVSLNSGYH-FCGGSLINSQWVVSAAHC-YKSGIQVRLGEDNINVV 58 Query: 89 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMC 148 E +Q + K +P Y+ T D+ L++L A +N V + LP GT C Sbjct: 59 EGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPT--SCASAGTQC 116 Query: 149 QVAGWGRTHNSA-SWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDS 207 ++GWG T +S S+ D L+ + I+ C + I NM CAG L GG DS Sbjct: 117 LISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSA----YPGQITSNMFCAG-LEGG-DS 170 Query: 208 CNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 C GDSG P++C G +G+ S+G + C + PGVY + +++WI TI Sbjct: 171 CQGDSGGPVVCSGKLQGIVSWG--SGCAKNK-PGVYTKVC-NYVSWIKQTI 217 >4XDE-A nrPDB Length = 257 Score = 117 bits (294), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 79/244 (32%), Positives = 121/244 (49%), Gaps = 23/244 (9%) Query: 28 KIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRS----QVILGAH 83 ++GG + PY+ L + CAG+LIA WVLTAAHC ++ + V+LG Sbjct: 2 SVVGGLVALRGAHPYIAALYWGH-SFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQE 60 Query: 84 SITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAK-----INKYVTILHLPKK 138 Q + V+ + + P + + DL LL+L E A ++ YV + LP Sbjct: 61 RRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSLPSG 120 Query: 139 GDDVKPGTMCQVAGWGRTHNSAS-WSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVC 197 T+CQVAGWG A ++ L+E + + + C+ + + + + GM +C Sbjct: 121 AARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGM--LC 178 Query: 198 AGSLRGGRDSCNGDSGSPLLCEG-------VFRGVTSFGLENKCGDPRGPGVYILLSKKH 250 AG L GG D+C GDSG PL+CE +G+ S+G + CGD PGVY ++ + Sbjct: 179 AGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWG--SGCGDRNKPGVYTDVA-YY 235 Query: 251 LNWI 254 L WI Sbjct: 236 LAWI 239 >3S9B-A nrPDB Length = 234 Score = 117 bits (293), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 79/235 (33%), Positives = 122/235 (51%), Gaps = 12/235 (5%) Query: 29 IIGGNEVTPHSRPYMVLL--SLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSIT 86 ++GG+E + P++V L S CAGALI ++WVLTAAHC+ + ++ LG HS Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIHCAGALINREWVLTAAHCD-RRNIRIKLGMHSKN 59 Query: 87 REEPTKQIMLVK-KEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 +QI + + K F P + D+ L++L + ++ + LP + V G Sbjct: 60 IRNEDEQIRVPRGKYFCLNTKFPNGLDKDIMLIRLRRPVTYSTHIAPVSLPSRSRGV--G 117 Query: 146 TMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 205 + C++ GWG+ ++ ++ D NI I+ K C Y + P + CAG L+GGR Sbjct: 118 SRCRIMGWGKI-STTTYPDVPHCTNIFIVKHKWCEPL--YPWVPADSRTL-CAGILKGGR 173 Query: 206 DSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 D+C+GDSG PL+C G G+ + G E CG P VY + + NWI I G Sbjct: 174 DTCHGDSGGPLICNGEMHGIVAGGSE-PCGQHLKPAVYTKVFDYN-NWIQSIIAG 226 >2V35-A nrPDB Length = 240 Score = 117 bits (293), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 73/237 (30%), Positives = 120/237 (50%), Gaps = 15/237 (6%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKT----ICAGALIAKDWVLTAAHC-NLNKRSQVILGAH 83 ++GG E +S P + L + C G LI ++WV+TAAHC + +V++G H Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEH 60 Query: 84 SITREEPTKQIMLVKK--EFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDD 141 ++ + + T+Q + V+K PY D D+ LL+L + +N YV + LP+ G Sbjct: 61 NLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRAGTI 120 Query: 142 VKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSL 201 + + C + GWG T + + TL++ + +D +C+ +++ + +MVCAG Sbjct: 121 LANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYW--GSTVKNSMVCAGG- 177 Query: 202 RGGRDSCNGDSGSPLLC----EGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 G R C GDSG PL C + GVTSF C R P V+ +S +++WI Sbjct: 178 DGVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVS-AYISWI 233 >2BDH-A nrPDB Length = 223 Score = 117 bits (292), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 79/232 (34%), Positives = 123/232 (53%), Gaps = 11/232 (4%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSI-TR 87 II G + +PHS+P+ L ++ + C+G L+ WVL+AAHC N + + LG HS+ Sbjct: 1 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYT-IGLGLHSLEAD 59 Query: 88 EEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTM 147 +EP Q++ +P Y+ DL L++L E +++ TI + G Sbjct: 60 QEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDES--VSESDTIRSISIASQCPTAGNS 117 Query: 148 CQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDS 207 C V+GWG N L+ VN++++ +VC+ ++P+ +M CAG + +DS Sbjct: 118 CLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCSKL----YDPLYHPSMFCAGGGQDQKDS 172 Query: 208 CNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 CNGDSG PL+C G +G+ SFG + CG PGVY L K WI T++ Sbjct: 173 CNGDSGGPLICNGYLQGLVSFG-KAPCGQVGVPGVYTNLC-KFTEWIEKTVQ 222 >1BRU-P nrPDB Length = 241 Score = 116 bits (291), Expect = 8e-27, Method: Compositional matrix adjust. Identities = 73/238 (30%), Positives = 117/238 (49%), Gaps = 16/238 (6%) Query: 29 IIGGNEVTPHSRPYMVLLSLDR----KTICAGALIAKDWVLTAAHCNLNKRS-QVILGAH 83 ++GG + P+S P+ V L D + C G L+ + WVLTAAHC + R+ +V+LG H Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRH 60 Query: 84 SITREEPTKQIMLVKKEFPYPCYDPA--TREGDLKLLQLMEKAKINKYVTILHLPKKGDD 141 S++ EP + V K + ++ + D+ LL+L + + + LP G Sbjct: 61 SLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAGTI 120 Query: 142 VKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSL 201 + +C V GWGR + + D L++ + ++D C+ + + NM+CAG Sbjct: 121 LPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWW--GSTVKTNMICAGG- 177 Query: 202 RGGRDSCNGDSGSPLLCEGV-----FRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 G SCNGDSG PL C+G G+ SFG C P V+ +S +++WI Sbjct: 178 DGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVS-NYIDWI 234 >6I44-A nrPDB Length = 627 Score = 116 bits (290), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 76/242 (31%), Positives = 126/242 (52%), Gaps = 23/242 (9%) Query: 28 KIIGGNEVTPHSRPYMVLLSLD---RKTICAGALIAKDWVLTAAHC-------NLNKRSQ 77 +I+GG + + P+ V L + ++ +C G+LI WVLTAAHC ++ + Sbjct: 379 RIVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 438 Query: 78 VILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPK 137 IL IT++ P QI K+ + Y + D+ L++L + ++ + LP Sbjct: 439 GILQLSDITKDTPFSQI---KEIIIHQNYKVSEGNHDIALIKLQAPLQYTEFQKPICLPS 495 Query: 138 KGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVC 197 KGD T C V GWG + + + L++VNI ++ + C R + I MVC Sbjct: 496 KGDTSTIYTNCWVTGWGFSAEAGEIQNILQKVNIPLVTNEECQKRYQ---DYKITQRMVC 552 Query: 198 AGSLRGGRDSCNGDSGSPLLCE--GVFR--GVTSFGLENKCGDPRGPGVYILLSKKHLNW 253 AG GG+D+C GD+G PL+C+ G++R G+TS+G C PGVY ++ ++++W Sbjct: 553 AGYKEGGKDACKGDAGGPLVCKHNGMWRLVGITSWG--EGCARREQPGVYTKVA-EYMDW 609 Query: 254 II 255 I+ Sbjct: 610 IL 611 >4GSO-A nrPDB Length = 232 Score = 116 bits (290), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 74/234 (31%), Positives = 122/234 (52%), Gaps = 12/234 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 ++GG+E + P++ L C LI ++WV+TAAHC+ + Q+ LG HS Sbjct: 1 VLGGDECDINEHPFLAFL-YSHGYFCGLTLINQEWVVTAAHCD-STNFQMQLGVHSKKVL 58 Query: 89 EPTKQIMLVKKEFPYPCYD-PATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTM 147 +Q K++F P + + D+ L++L + +K++ L LP V G++ Sbjct: 59 NEDEQTRNPKEKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPSNPPSV--GSV 116 Query: 148 CQVAGWGR-THNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRD 206 C++ GWG T + ++ D NI ++D +VC +N + +CAG L GG+D Sbjct: 117 CRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGA----YNGLPAKTTLCAGVLEGGKD 172 Query: 207 SCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 +C GDSG PL+C G F+G+ S+G + CG PG+Y + + +WI I G Sbjct: 173 TCVGDSGGPLICNGQFQGIVSYG-AHSCGQGPKPGIYTNVF-DYTDWIQRNIAG 224 >2PSX-A nrPDB Length = 227 Score = 114 bits (286), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 79/235 (33%), Positives = 119/235 (50%), Gaps = 13/235 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSL-DRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITR 87 II G++ H++P+ L L + C L+ W+LTAAHC K +V LG +S++ Sbjct: 1 IINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCR-KKVFRVRLGHYSLSP 59 Query: 88 -EEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGT 146 E +Q+ K P+P Y DL L++L + + K V +++ GT Sbjct: 60 VYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSA--GT 117 Query: 147 MCQVAGWGRTHN-SASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 205 C V+GWG T + + L+ +NI+++ +K C D + I M CAG + GR Sbjct: 118 KCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDA----YPRQIDDTMFCAGD-KAGR 172 Query: 206 DSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 DSC GDSG P++C G +G+ S+G + C P PGVY L K WI TI+ Sbjct: 173 DSCQGDSGGPVVCNGSLQGLVSWG-DYPCARPNRPGVYTNLC-KFTKWIQETIQA 225 >1X7A-C nrPDB Length = 235 Score = 114 bits (285), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 77/236 (32%), Positives = 117/236 (49%), Gaps = 18/236 (7%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHC-NLNKRSQVILGAHSITR 87 I+GG P P+ VLL+ C G++I + WV+TAAHC + V+ G ++ Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVAGEYNTEE 60 Query: 88 EEPTKQIMLVKKEFPYPCYDPATRE--GDLKLLQLMEKAKINKYVTILHLPKKGDD---V 142 EPT+Q V + P+ Y+ + D+ LL+L E +N YVT + + K + Sbjct: 61 TEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEYTNIFL 120 Query: 143 KPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 202 K G+ V+GWGR N + L+ + + ++DR C + I NM CAG Sbjct: 121 KFGSG-YVSGWGRVFNRGRSATILQYLKVPLVDRATCLRSTKF----TIYSNMFCAGFHE 175 Query: 203 GGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 GG+DSC GDSG P + E G+ S+G E C G+Y +S +++NWI Sbjct: 176 GGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEE--CAVKGKYGIYTKVS-RYVNWI 228 >2AIQ-A nrPDB Length = 231 Score = 112 bits (280), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 73/234 (31%), Positives = 119/234 (50%), Gaps = 13/234 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSI-TR 87 +IGG+E + ++ L+ + ++C G LI ++WVLTA HC+ ++ LG H++ Sbjct: 1 VIGGDECNINEHRFLALVYAN-GSLCGGTLINQEWVLTARHCDRGNM-RIYLGMHNLKVL 58 Query: 88 EEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTM 147 + + +K F + + D+ L++L + + ++ L LP V G++ Sbjct: 59 NKDALRRFPKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPSNPPSV--GSV 116 Query: 148 CQVAGWGR-THNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRD 206 C++ GWG T +A+ D NI I+D VC + +CAG L GG+D Sbjct: 117 CRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAYKG-----LAATTLCAGILEGGKD 171 Query: 207 SCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 +C GDSG PL+C G F+G+ S G N C PR PG+Y + + +WI I G Sbjct: 172 TCKGDSGGPLICNGQFQGILSVG-GNPCAQPRKPGIYTKVF-DYTDWIQSIISG 223 >1AZZ-A nrPDB Length = 226 Score = 112 bits (279), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 70/209 (33%), Positives = 108/209 (51%), Gaps = 12/209 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHC-NLNKRSQVILGAHSITR 87 I+GG E P+S P+ L +D C G+LI+ +W+LTAAHC + V+LGAH+I R Sbjct: 1 IVGGVEAVPNSWPHQAALFIDDMYFCGGSLISPEWILTAAHCMDGAGFVDVVLGAHNI-R 59 Query: 88 EEPTKQIMLVKKEFP-YPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGT 146 E+ Q+ + +F + Y+ D+ +++L + + + LP DV GT Sbjct: 60 EDEATQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPST--DVGVGT 117 Query: 147 MCQVAGWGRTHNSA-SWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 205 + GWG +SA SD LR+V++ I+ C+ ++ +C S GG+ Sbjct: 118 VVTPTGWGLPSDSALGISDVLRQVDVPIMSNADCD-----AVYGIVTDGNICIDS-TGGK 171 Query: 206 DSCNGDSGSPLLCEGVFRGVTSFGLENKC 234 +CNGDSG PL G+ G+TSFG C Sbjct: 172 GTCNGDSGGPLNYNGLTYGITSFGAAAGC 200 >4IGD-A nrPDB Length = 406 Score = 112 bits (279), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 78/274 (28%), Positives = 131/274 (47%), Gaps = 30/274 (10%) Query: 6 RFLASSLSVVVSLLLIPE---DVCEKIIGGNEVTPHSRPYMVLLS-LDRKTICAGALIAK 61 + L SL + + +P+ + +I G + P++ +LS L+ + C G+L+ Sbjct: 130 KVLGRSLPTCLPVCGLPKFSRKLMAQIFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGS 189 Query: 62 DWVLTAAHC---NLNKRS--------------QVILGAHSITREEPTKQIMLVKKEFPYP 104 W++TAAHC +L+ ++ILG H R + +Q + VK +P Sbjct: 190 SWIVTAAHCLHQSLDPEDPTLRDSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHP 249 Query: 105 CYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSD 164 YDP T E D+ L++L+E +N +V + LP+ + G M V+GWG+ + + Sbjct: 250 QYDPNTFENDVALVELLESPVLNAFVMPICLPEGPQ--QEGAMVIVSGWGKQF-LQRFPE 306 Query: 165 TLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRG 224 TL E+ I I+D C + + + +M+CAG GG+D+C GDSG P++ RG Sbjct: 307 TLMEIEIPIVDHSTCQ-KAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERG 365 Query: 225 ----VTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 V + + CG GVY + +WI Sbjct: 366 QWYLVGTVSWGDDCGKKDRYGVYSYIHHNK-DWI 398 >4DJZ-B nrPDB Length = 251 Score = 111 bits (277), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 74/248 (29%), Positives = 121/248 (48%), Gaps = 27/248 (10%) Query: 29 IIGGNEVTPHSRPYMVLLS-LDRKTICAGALIAKDWVLTAAHC---NLNKRS-------- 76 I G + P++ +LS L+ + C G+L+ W++TAAHC +L+ + Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDSDL 60 Query: 77 ------QVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYV 130 ++ILG H R + +Q + VK +P YDP T E D+ L++L+E +N +V Sbjct: 61 LSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLNAFV 120 Query: 131 TILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPV 190 + LP+ + G M V+GWG+ + +TL E+ I I+D C + + Sbjct: 121 MPICLPEGPQ--QEGAMVIVSGWGKQF-LQRFPETLMEIEIPIVDHSTCQ-KAYAPLKKK 176 Query: 191 IGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRG----VTSFGLENKCGDPRGPGVYILL 246 + +M+CAG GG+D+C GDSG P++ RG V + + CG GVY + Sbjct: 177 VTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKKDRYGVYSYI 236 Query: 247 SKKHLNWI 254 +WI Sbjct: 237 HHNK-DWI 243 >2CGA-A nrPDB Length = 245 Score = 111 bits (277), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 77/240 (32%), Positives = 118/240 (49%), Gaps = 19/240 (7%) Query: 27 EKIIGGNEVTPHSRPYMVLLSLDRKT---ICAGALIAKDWVLTAAHCNLNKRSQVILGAH 83 +I+ G E P S P+ V SL KT C G+LI ++WV+TAAHC + V+ G Sbjct: 14 SRIVNGEEAVPGSWPWQV--SLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEF 71 Query: 84 SITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVK 143 Q + + K F Y+ T D+ LL+L A ++ V+ + LP DD Sbjct: 72 DQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFA 131 Query: 144 PGTMCQVAGWGRT-HNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 202 GT C GWG T + +A+ D L++ ++ ++ C + I M+CAG+ Sbjct: 132 AGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKY----WGTKIKDAMICAGA-- 185 Query: 203 GGRDSCNGDSGSPLLCE--GVFR--GVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 G SC GDSG PL+C+ G + G+ S+G + C PGVY ++ +NW+ T+ Sbjct: 186 SGVSSCMGDSGGPLVCKKNGAWTLVGIVSWG-SSTCSTST-PGVYARVT-ALVNWVQQTL 242 >3LC3-A nrPDB Length = 235 Score = 111 bits (277), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 75/236 (31%), Positives = 119/236 (50%), Gaps = 18/236 (7%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHC-NLNKRSQVILGAHSITR 87 ++GG + P P+ V+L+ C G+++ + W++TAAHC + V+ G H+I Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEE 60 Query: 88 EEPTKQIMLVKKEFPYPCYDPATRE--GDLKLLQLMEKAKINKYVTILHLPKKGDD---V 142 E T+Q V + P+ Y+ A + D+ LL+L E +N YVT + + K + Sbjct: 61 TEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFL 120 Query: 143 KPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 202 K G+ V+GWGR + + L+ + + ++DR C + I NM CAG Sbjct: 121 KFGSG-YVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKF----TIYNNMFCAGFHE 175 Query: 203 GGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 GGRDSC GDSG P + E G+ S+G E C G+Y +S +++NWI Sbjct: 176 GGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEE--CAMKGKYGIYTKVS-RYVNWI 228 >5GVT-A nrPDB Length = 250 Score = 110 bits (276), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 74/245 (30%), Positives = 120/245 (48%), Gaps = 31/245 (12%) Query: 29 IIGGNEVTPHSRPYMVLLSL---DRKTICAGALIAKDWVLTAAHC-------NLNKRSQV 78 I+GG + P+ V L + + +C G++I + WVLTAAHC ++ + Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 79 ILGAHSITREEPTKQI--MLVKKEFPYPCYDPATREG--DLKLLQLMEKAKINKYVTILH 134 IL IT+E P+ +I +++ +E+ EG D+ L++L ++ + Sbjct: 61 ILSLSEITKETPSSRIKELIIHQEY-------KVSEGNYDIALIKLQTPLNYTEFQKPIS 113 Query: 135 LPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMN 194 LP K D T C V GWG T + L++ I ++ + C + + VI Sbjct: 114 LPSKADTNTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYR---DYVINKQ 170 Query: 195 MVCAGSLRGGRDSCNGDSGSPLLCEGVFR----GVTSFGLENKCGDPRGPGVYILLSKKH 250 M+CAG GG D+C GDSG PL+C+ R G+TS+G C PGVY +S ++ Sbjct: 171 MICAGYKEGGTDACKGDSGGPLVCKHSGRWQLVGITSWG--EGCARKDQPGVYTKVS-EY 227 Query: 251 LNWII 255 ++WI+ Sbjct: 228 MDWIL 232 >1GVZ-A nrPDB Length = 237 Score = 109 bits (272), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 79/243 (32%), Positives = 120/243 (49%), Gaps = 21/243 (8%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 IIGG E HS+P+ V + C G L+ WVLTAAHC ++ Q+ LG H+++++ Sbjct: 1 IIGGWECEKHSKPWQVAVYHQGHFQCGGVLVHPQWVLTAAHC-MSDDYQIWLGRHNLSKD 59 Query: 89 EPTKQIMLVKKEFPYPCYDPATREG-----------DLKLLQLMEKAKINKYVTILHLPK 137 E T Q V F P +D + + DL LL+L + A+I V IL LP Sbjct: 60 EDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVKILDLPT 119 Query: 138 KGDDVKPGTMCQVAGWGRTHN-SASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMV 196 + + K G+ C +GWG + S TL+ V + R N++ + + ++ Sbjct: 120 Q--EPKLGSTCYTSGWGLISTFTNRGSGTLQCVEL----RLQSNEKCARAYPEKMTEFVL 173 Query: 197 CAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIM 256 CA C GDSG L+C+GVF+G+TS+G ++C D V+ + H WI Sbjct: 174 CATHRDDSGSICLGDSGGALICDGVFQGITSWGY-SECADFNDNFVFTKV-MPHKKWIKE 231 Query: 257 TIK 259 TI+ Sbjct: 232 TIE 234 >4MPW-A nrPDB Length = 245 Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 78/243 (32%), Positives = 120/243 (49%), Gaps = 23/243 (9%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKT---ICAGALIAKDWVLTAAHCNLNKRSQVILGAHSI 85 I+GG E P+ V L + C G+LI WVLTAAHC + + + Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHC-VGPDVKDLAALRVQ 59 Query: 86 TREEP---TKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDV 142 RE+ Q++ V + +P + A D+ LL+L E K++ +V + LP + Sbjct: 60 LREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASETF 119 Query: 143 KPGTMCQVAGWGRTHNSASWSD--TLREVNITIIDRKVCNDRNH---YNFNPV--IGMNM 195 PG C V GWG N L++V + I++ +C+ + H Y + V + +M Sbjct: 120 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 179 Query: 196 VCAGSLRGGRDSCNGDSGSPLLCE--GVF--RGVTSFGLENKCGDPRGPGVYILLSKKHL 251 +CAG+ R RDSC GDSG PL+C+ G + GV S+G C P PG+Y ++ +L Sbjct: 180 LCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWG--EGCAQPNRPGIYTRVT-YYL 234 Query: 252 NWI 254 +WI Sbjct: 235 DWI 237 >2OQ5-A nrPDB Length = 232 Score = 107 bits (266), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 68/231 (29%), Positives = 105/231 (45%), Gaps = 10/231 (4%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 I+GG EV P+ L D C LI W+++AAHC ++ A Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGVTI 60 Query: 89 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMC 148 +P+K +++ + Y + + D+ L +L V + LP + +PG + Sbjct: 61 KPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVM 120 Query: 149 QVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSC 208 V G+G N + LR+ +T+ID CN+ Y N I M+CAGSL G D+C Sbjct: 121 FVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAY--NDAITPRMLCAGSLEGKTDAC 178 Query: 209 NGDSGSPLLCEGV-----FRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 GDSG PL+ G+ S+G ++C P PGVY ++ +WI Sbjct: 179 QGDSGGPLVSSDARDIWYLAGIVSWG--DECAKPNKPGVYTRVTALR-DWI 226 >5XRF-A nrPDB Length = 242 Score = 107 bits (266), Expect = 8e-24, Method: Compositional matrix adjust. Identities = 81/241 (33%), Positives = 123/241 (51%), Gaps = 18/241 (7%) Query: 27 EKIIGGNEVTPHSRPYMVLLSLDRKTI--CAGALIAKDWVLTAAHCNLNKRSQVILGAHS 84 E +IGGNE + ++ R CAG LI ++WVL AAHC + + LG H+ Sbjct: 5 ELVIGGNECDTNEHRFLAAFFTSRPWTFQCAGTLIHEEWVLAAAHC-YKRGLNIYLGMHN 63 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPATR-EGDLKLLQLMEKAKINKYVTILHLPKKGDDVK 143 + + +Q +E Y C + T+ E D+ LL+L + + ++ L LP + Sbjct: 64 QSIQFDDEQRRYAIEEHYYRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPLSLPSSPPSI- 122 Query: 144 PGTMCQVAGWGRTHNSASWSDTLREV----NITIIDRKVCNDRNHYNFNPVIGMNMVCAG 199 G++C+V GWG +S D L +V NI +++ C HY P ++CAG Sbjct: 123 -GSVCRVMGWGIM---SSTKDILPDVPHCANINLLNYMEC--VAHYPDVPET-TRLLCAG 175 Query: 200 SLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 L GG D+CN DSG PL+C+G F+G+ FG + C P PG+Y +S + +WI I Sbjct: 176 VLEGGIDTCNQDSGGPLICDGQFQGIVFFG-KYPCAQPNKPGLYTRVSNYN-DWIQNIIA 233 Query: 260 G 260 G Sbjct: 234 G 234 >1FON-A nrPDB Length = 240 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 73/241 (30%), Positives = 120/241 (49%), Gaps = 19/241 (7%) Query: 32 GNEVTPHSRPYMVLLSLDRKT----ICAGALIAKDWVLTAAHCNLNKRS-QVILGAHSIT 86 G + P+S + V L ++ C G+LIA DWV+TA HC R+ QV+LG + + Sbjct: 2 GEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSRTYQVVLGEYDRS 61 Query: 87 REEPTKQIMLVKKE--FPYPCYDP--ATREGDLKLLQLMEKAKINKYVTILHLPKKGDDV 142 E ++Q++ + F +P ++ D+ L++L A++ V + +LP GD + Sbjct: 62 VLEGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPAGDIL 121 Query: 143 KPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 202 C ++GWGR + D L++ + +D + C+ + + + MVCAG Sbjct: 122 PNEAPCYISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQWDWWGI--TVKKTMVCAGGDT 179 Query: 203 GGRDSCNGDSGSPLLC---EGVFR--GVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMT 257 R CNGDSG PL C +G ++ GVTSF C + P V+ +S ++WI T Sbjct: 180 --RSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVS-AFIDWIDET 236 Query: 258 I 258 I Sbjct: 237 I 237 >1FXY-A nrPDB Length = 228 Score = 105 bits (262), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 71/233 (30%), Positives = 116/233 (49%), Gaps = 12/233 (5%) Query: 29 IIGGNEVTPHSRPYMVLL-SLDRKTICAGALIAKDWVLTAAHCNLN-KRSQVILGAHSIT 86 I+GG P+ LL + + + C G ++++ ++LTAAHC KR +V +G + Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTE 60 Query: 87 REEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGT 146 +EE + + V+ + + T + D+ +L+L V LP GT Sbjct: 61 QEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLPTA--PPATGT 118 Query: 147 MCQVAGWGRTHNS-ASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 205 C ++GWG T +S A + D L+ ++ ++ + C ++ I NM C G L GG+ Sbjct: 119 KCLISGWGNTASSGADYPDELQCLDAPVLSQAKC----EASYPGKITSNMFCVGFLEGGK 174 Query: 206 DSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 DSC GDSG P++C G +GV S+G + C PGVY + ++ WI TI Sbjct: 175 DSCQGDSGGPVVCNGQLQGVVSWG--DGCAQKNKPGVYTKVY-NYVKWIKNTI 224 >4H4F-A nrPDB Length = 249 Score = 104 bits (259), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 71/238 (29%), Positives = 120/238 (50%), Gaps = 17/238 (7%) Query: 29 IIGGNEVTPHSRPYMVLLSLDR----KTICAGALIAKDWVLTAAHCNLNKRS-QVILGAH 83 ++GG + PHS P+ + L + + C G LIA ++VLTAAHC N R+ +V +G + Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 60 Query: 84 SITREEPTKQIML-VKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDV 142 ++ E+ + + V + ++ D+ L++L E +++ + + LP+K + Sbjct: 61 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 120 Query: 143 KPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 202 C V GWGR + +D L++ ++D C+ + + F + MVCAG Sbjct: 121 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFR--VKKTMVCAGG-D 177 Query: 203 GGRDSCNGDSGSPLLCE------GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 G +CNGDSG PL C+ VF G+ SFG C + P VY +S +++WI Sbjct: 178 GVISACNGDSGGPLNCQLENGSWEVF-GIVSFGSRRGCNTRKKPVVYTRVS-AYIDWI 233 >1PYT-D nrPDB Length = 251 Score = 104 bits (259), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 69/245 (28%), Positives = 120/245 (48%), Gaps = 14/245 (5%) Query: 20 LIPEDVCEKIIGGNEVTPHSRPYMVLLSLDR----KTICAGALIAKDWVLTAAHCNLNKR 75 + ++ +++GG + PHS P+ + L R + C G LI + VLTAAHC N Sbjct: 5 IFQPNLSARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCISNTL 64 Query: 76 S-QVILGAHSITREEPTKQIML-VKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTIL 133 + +V LG +++ E+ + + V F + ++ D+ L++L E ++ + + Sbjct: 65 TYRVALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELGDTIQVA 124 Query: 134 HLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGM 193 LP +G + C V GWGR + + + L++ ++D C+ R+ + + Sbjct: 125 CLPSEGSLLPQDYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQRDWW--GTTVKE 182 Query: 194 NMVCAGSLRGGRDSCNGDSGSPLLCEG----VFRGVTSFGLENKCGDPRGPGVYILLSKK 249 MVCAG G +CNGDSG PL C+ RG+ SFG C + P V+ +S Sbjct: 183 TMVCAGG-DGVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPTVFTRVS-A 240 Query: 250 HLNWI 254 +++WI Sbjct: 241 YIDWI 245 >1FIZ-A nrPDB Length = 263 Score = 103 bits (258), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 82/254 (32%), Positives = 116/254 (45%), Gaps = 30/254 (11%) Query: 29 IIGGNEVTPHSRPYMVLLSL------DRKTICAGALIAKDWVLTAAHCNLNKRS----QV 78 ++GG P + P+MV L + R C G L+ WVLTAAHC NK+ ++ Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 79 ILGAHSITRE-----EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTIL 133 I GA+ + +P Q V++ + Y D+ L+++ ++ Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGPG 120 Query: 134 HLP--KKGDDVKPGTMCQVAGWGR-THNSASWSDTLREVNITIIDRKVCNDRNHYNFNPV 190 LP K G P T C V GWG S TL+E + +ID ++CN YN Sbjct: 121 CLPQFKAGPPRAPQT-CWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGR-- 177 Query: 191 IGMNMVCAGSLRGGRDSCNGDSGSPLLCEG------VFRGVTSFGLENKCGDPRGPGVYI 244 I VCAG RG D+C GDSG PL+C V G+TS+G+ C + PGVY Sbjct: 178 IRSTNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGV--GCARAKRPGVYT 235 Query: 245 LLSKKHLNWIIMTI 258 + +LNWI I Sbjct: 236 -STWPYLNWIASKI 248 >1OP0-A nrPDB Length = 234 Score = 103 bits (258), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 74/235 (31%), Positives = 120/235 (51%), Gaps = 12/235 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 +IGGNE + ++V C G LI +WV+TAAHC+ + Q+ LG HS Sbjct: 1 VIGGNECDINEHRFLVAFFNTTGFFCGGTLINPEWVVTAAHCD-STDFQMQLGVHSKKVL 59 Query: 89 EPTKQIMLVKKEFPYPCYDP-ATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTM 147 +Q K++F P + + D+ L++L + +K++ L LP V G++ Sbjct: 60 NEDEQTRNPKEKFICPNKNNNEVLDKDIMLIKLDKPISNSKHIAPLSLPSSPPSV--GSV 117 Query: 148 CQVAGWGR-THNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIG-MNMVCAGSLRGGR 205 C++ GWG T ++ D NI ++D VC + ++ +CAG ++GG+ Sbjct: 118 CRIMGWGSITPVKETFPDVPYCANINLLDHAVC----QAGYPELLAEYRTLCAGIVQGGK 173 Query: 206 DSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 D+C GDSG PL+C G F+G+ S+G + CG PG+Y + + +WI I G Sbjct: 174 DTCGGDSGGPLICNGQFQGIVSYG-AHPCGQGPKPGIYTNVF-DYTDWIQRNIAG 226 >3S69-A nrPDB Length = 234 Score = 103 bits (257), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 76/234 (32%), Positives = 116/234 (49%), Gaps = 10/234 (4%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 +IGG+E + +V C+G LI ++WVLTAAHC+ N Q+ LG HS Sbjct: 1 VIGGDECNINEHRSLVAFFNSTGFFCSGTLINEEWVLTAAHCD-NTNFQMKLGVHSKKVL 59 Query: 89 EPTKQIMLVKKEFPYPCY-DPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTM 147 +Q K++F P + + D+ L++L + ++++ L LP V G++ Sbjct: 60 NEDEQTRNPKEKFICPNKKNDEVLDKDIMLIKLDSRVSNSEHIVPLSLPSSPPSV--GSV 117 Query: 148 CQVAGWGR-THNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRD 206 C + GWG T ++ D I ++D VC + +CAG L GG+D Sbjct: 118 CHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYP---ELLTEYRTLCAGILEGGKD 174 Query: 207 SCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 +C GDSG PL+C G F+G+ SFG + CG PGVY + + +WI I G Sbjct: 175 TCGGDSGGPLICNGQFQGIVSFG-AHPCGQGLKPGVYTKVFDYN-HWIQSIIAG 226 >1LTO-A nrPDB Length = 245 Score = 103 bits (256), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 76/241 (31%), Positives = 116/241 (48%), Gaps = 19/241 (7%) Query: 29 IIGGNEVTPHSRPYMVLLSL-DRKTI--CAGALIAKDWVLTAAHCNLNKRSQVILGAHSI 85 I+GG E P+ V L + DR + C G+LI WVLTAAHC L + + Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHC-LGPDVKDLATLRVQ 59 Query: 86 TREEP---TKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDV 142 RE+ Q++ V + +P + D+ LL+L E I+ V + LP + Sbjct: 60 LREQHLYYQDQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPASETF 119 Query: 143 KPGTMCQVAGWGRTHNSASWSD--TLREVNITIIDRKVCNDRNH---YNFNPV--IGMNM 195 PG C V GWG N L++V + I++ +C+ + H Y + V I +M Sbjct: 120 PPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIIRDDM 179 Query: 196 VCAGSLRGGRDSCNGDSGSPLLCE--GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNW 253 +CAG+ + RDSC GDSG PL+C+ G + + C P PG+Y ++ +L+W Sbjct: 180 LCAGNSQ--RDSCKGDSGGPLVCKVNGTWLQAGVVSWDEGCAQPNRPGIYTRVT-YYLDW 236 Query: 254 I 254 I Sbjct: 237 I 237 >1FIW-A nrPDB Length = 290 Score = 102 bits (255), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 81/254 (31%), Positives = 119/254 (46%), Gaps = 30/254 (11%) Query: 29 IIGGNEVTPHSRPYMVLLSL------DRKTICAGALIAKDWVLTAAHCNLNKRS----QV 78 IIGG + + P+MV L + R +C G+L+ W+LTAAHC K+ ++ Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 79 ILGAHSITRE-----EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTIL 133 I GA + +P Q V+K + Y ++ D+ L+++ ++ Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGPG 120 Query: 134 HLP--KKGDDVKPGTMCQVAGWGR-THNSASWSDTLREVNITIIDRKVCNDRNHYNFNPV 190 LP + G P T C VAGWG N+ S L+E + +ID +CN YN Sbjct: 121 CLPQFRAGPPRVPQT-CWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGR-- 177 Query: 191 IGMNMVCAGSLRGGRDSCNGDSGSPLLCEG------VFRGVTSFGLENKCGDPRGPGVYI 244 I VCAG G D+C GDSG PL+C+ V G+TS+G+ C + PGVY Sbjct: 178 IRSTNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGV--GCARAKRPGVYT 235 Query: 245 LLSKKHLNWIIMTI 258 + +LNWI I Sbjct: 236 -STWSYLNWIASKI 248 >5LPF-A nrPDB Length = 234 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 80/238 (33%), Positives = 115/238 (48%), Gaps = 22/238 (9%) Query: 32 GNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITREEPT 91 G+ S+P+ V L CAG L+ + WVLTAAHC NK +G + + Sbjct: 7 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCG-NKPLWARVGDDHLLLLQ-G 64 Query: 92 KQIMLVKKEFPYPCYDPA--------TREGDLKLLQLMEKAKINKYVTILHLPKKGDDVK 143 +Q+ + +P Y T E DL LL+L + V L LP + + Sbjct: 65 EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRC--AQ 122 Query: 144 PGTMCQVAGWGRTH-NSASWSDTLREVNITIIDRKVCNDRNHYNFNP-VIGMNMVCAGSL 201 PG CQVAGWG T ++ L +ITI+ K C F P V+ NM+CAG L Sbjct: 123 PGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECE-----VFYPGVVTNNMICAG-L 176 Query: 202 RGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 G+D C DSG PL+C+ +G+ S+G+ CG + P VY + K+++WI I+ Sbjct: 177 DRGQDPCQSDSGGPLVCDETLQGILSWGVY-PCGSAQHPAVYTQIC-KYMSWINKVIR 232 >2F91-A nrPDB Length = 237 Score = 100 bits (248), Expect = 9e-22, Method: Compositional matrix adjust. Identities = 70/242 (28%), Positives = 112/242 (46%), Gaps = 26/242 (10%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTI------CAGALIAKDWVLTAAHCNLNKRS------ 76 I+GG + T PY LS I C ++ +++ +TA HC Sbjct: 1 IVGGTDATLGEFPYQ--LSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGL 58 Query: 77 QVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLP 136 Q++ G ++ E ++QI+ V K + +D + D+ LL+L N V + LP Sbjct: 59 QIVAGELDMSVNEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALP 118 Query: 137 KKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMV 196 ++G + V GWG T + D L++V + ++ + C R Y + ++ +M+ Sbjct: 119 EQGHTATGDVI--VTGWGTTSEGGNTPDVLQKVTVPLVSDEDC--RADYGADEILD-SMI 173 Query: 197 CAGSLRGGRDSCNGDSGSPLLCEGV----FRGVTSFGLENKCGDPRGPGVYILLSKKHLN 252 CAG GG+DSC GDSG PL G+ S+G C P PGVY +S H++ Sbjct: 174 CAGVPEGGKDSCQGDSGGPLAASDTGSTYLAGIVSWGY--GCARPGYPGVYTEVS-YHVD 230 Query: 253 WI 254 WI Sbjct: 231 WI 232 >3P8G-A nrPDB Length = 241 Score = 99.4 bits (246), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 71/234 (30%), Positives = 111/234 (47%), Gaps = 22/234 (9%) Query: 29 IIGGNEVTPHSRPYMVLL-SLDRKTICAGALIAKDWVLTAAHCNLNKRS---------QV 78 ++GG + P+ V L +L + IC +LI+ +W+++AAHC ++ R Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTA 60 Query: 79 ILGAHSIT-REEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPK 137 LG H + R P Q +K+ +P ++ T + D+ LL+L + A+ + V + LP Sbjct: 61 FLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICLPD 120 Query: 138 KGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVC 197 G V GWG T + + L++ I +I + C + P M+C Sbjct: 121 ASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVIQQTTCENLLPQQITP----RMMC 176 Query: 198 AGSLRGGRDSCNGDSGSPLL---CEG-VFR-GVTSFGLENKCGDPRGPGVYILL 246 G L GG DSC GDSG PL +G +F+ GV S+G + C PGVY L Sbjct: 177 VGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWG--DGCAQRNKPGVYTRL 228 >1A5I-A nrPDB Length = 265 Score = 97.8 bits (242), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 73/228 (32%), Positives = 114/228 (50%), Gaps = 26/228 (11%) Query: 47 SLDRKTICAGALIAKDWVLTAAHC----NLNKRSQVILGAHSITREEPTKQIMLVKKEFP 102 S + +C G LI+ WVLTAAHC L + +V+LG + +Q VKK Sbjct: 38 SSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVVLGRTYRVKPGEEEQTFKVKKYIV 97 Query: 103 YPCYDPATREGDLKLLQLMEK----AKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHN 158 + +D T D+ LLQL A+ + V + LP+ + T C+++G+G+ H Sbjct: 98 HKEFDDDTYNNDIALLQLKSDSPQCAQESDSVRAICLPEANLQLPDWTECELSGYGK-HK 156 Query: 159 SAS--WSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR------DSCNG 210 S+S +S+ L+E ++ + C + + FN + NM+CAG R G D+C G Sbjct: 157 SSSPFYSEQLKEGHVRLYPSSRCAPK--FLFNKTVTNNMLCAGDTRSGEIYPNVHDACQG 214 Query: 211 DSGSPLLCEG----VFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 DSG PL+C G+ S+G+ CG+ PGVY ++ +L WI Sbjct: 215 DSGGPLVCMNDNHMTLLGIISWGV--GCGEKDVPGVYTKVT-NYLGWI 259 >6AOD-C nrPDB Length = 245 Score = 97.4 bits (241), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 72/238 (30%), Positives = 110/238 (46%), Gaps = 17/238 (7%) Query: 29 IIGGNEVTPHSRPYMVLL---SLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHS- 84 I+GG P+ V L S ++ +C G++I W+LTAAHC S IL +S Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 85 ITREEPTKQ---IMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDD 141 I ++ K+ V++ + Y A D+ LL+L + + LP KGD Sbjct: 61 ILQQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKGDR 120 Query: 142 VKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSL 201 T C V GWG +TL++ I ++ + C R I M+CAG Sbjct: 121 NVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYR---GHKITHKMICAGYR 177 Query: 202 RGGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWII 255 GG+D+C GD+G PL C+ G+TS+G C PGVY + ++++WI+ Sbjct: 178 EGGKDACKGDAGGPLSCKHNEVWHLVGITSWG--EGCAQRERPGVYTNVV-EYVDWIL 232 >2F83-A nrPDB Length = 625 Score = 95.9 bits (237), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 73/239 (30%), Positives = 109/239 (45%), Gaps = 17/239 (7%) Query: 28 KIIGGNEVTPHSRPYMVLL---SLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHS 84 +I+GG P+ V L S ++ +C G++I W+LTAAHC S IL +S Sbjct: 387 RIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYS 446 Query: 85 -ITREEPTKQ---IMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGD 140 I + K+ V++ + Y A D+ LL+L + LP KGD Sbjct: 447 GILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGD 506 Query: 141 DVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGS 200 T C V GWG +TL++ I ++ + C R I M+CAG Sbjct: 507 RNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYR---GHKITHKMICAGY 563 Query: 201 LRGGRDSCNGDSGSPLLCEG----VFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWII 255 GG+D+C GDSG PL C+ G+TS+G C PGVY + ++++WI+ Sbjct: 564 REGGKDACKGDSGGPLSCKHNEVWHLVGITSWG--EGCAQRERPGVYTNVV-EYVDWIL 619 >5KWM-A nrPDB Length = 230 Score = 93.6 bits (231), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 68/221 (30%), Positives = 103/221 (46%), Gaps = 19/221 (8%) Query: 29 IIGGNEVTPHSRPYMV-LLSLDRKTICAGALIAKDWVLTAAHCNLNKRS---QVILGAHS 84 I+GG + P+ V L++ D + C G L A + V+TAAHC + + V+ G Sbjct: 1 IVGGEDANVQDHPFTVALVTPDGQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSGRTV 60 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDV-- 142 ++ E T + V + +P Y A + D+ +L L +A + + L K DD Sbjct: 61 MSSNEGT--VSKVTNVWVHPEYQDAAKGFDVSVLTL--EAPVKEAPIEL---AKADDAGY 113 Query: 143 KPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 202 P T + GWG T +D L++ + + C + + + P MVCAG Sbjct: 114 APDTAATILGWGNTSEGGQQADHLQKATVPVNSDDTCK-QAYGEYTPDA---MVCAGVPE 169 Query: 203 GGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVY 243 GG D+C GDSG P++ GVTS+G C P PGVY Sbjct: 170 GGVDTCQGDSGGPMVVNNKLIGVTSWG--EGCARPGKPGVY 208 >2PKA-B nrPDB Length = 152 Score = 92.8 bits (229), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 53/148 (35%), Positives = 83/148 (56%), Gaps = 11/148 (7%) Query: 114 DLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTH---NSASWSDTLREVN 170 DL LL+L AKI V +L LP + ++ G+ C+ +GWG + + D ++ V Sbjct: 9 DLMLLRLQSPAKITDAVKVLELPTQEPEL--GSTCEASGWGSIEPGPDDFEFPDEIQCVQ 66 Query: 171 ITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGL 230 +T++ C D + + +M+CAG L GG+D+C GDSG PL+C G+++G+TS+G Sbjct: 67 LTLLQNTFCADAHPDK----VTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQGITSWG- 121 Query: 231 ENKCGDPRGPGVYILLSKKHLNWIIMTI 258 CG P +Y L +L+WI TI Sbjct: 122 HTPCGSANKPSIYTKL-IFYLDWIDDTI 148 >2XXL-A nrPDB Length = 408 Score = 92.0 bits (227), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 78/266 (29%), Positives = 125/266 (46%), Gaps = 44/266 (16%) Query: 27 EKIIGGNEVTPHSRPYMVLLSLDR----KTICAGALIAKDWVLTAAHCN---LNKRSQVI 79 +++ G EV SRP+M LL + + +C GA+I++ ++LTAAHC N ++ Sbjct: 117 QRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDLYEIR 176 Query: 80 LGAHSITREEPTKQIMLVKKEFP------------YPCYDPATREGDLKLLQLMEKAKIN 127 LG H I+ EE +Q KK P + YD D+ LL+L Sbjct: 177 LGEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNRSVPFQ 236 Query: 128 KYVTILHLPKKGDDVKPG----TMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRN 183 K++ + LP D++K + V GWG T N +S SD L + N+ + R C+ Sbjct: 237 KHIKPICLPIT-DELKEKAEQISTYFVTGWGTTENGSS-SDVLLQANVPLQPRSACSQ-- 292 Query: 184 HYNFNPVIGMNMVCAGSLRGG--RDSCNGDSGSPLLCEGVFRG-----VTSFGLENK--- 233 + + ++ +C G GG +DSC GDSG PL + G + FG+ ++ Sbjct: 293 --AYRRAVPLSQLCVG---GGDLQDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVV 347 Query: 234 -CGDPRGPGVYILLSKKHLNWIIMTI 258 CG PG+Y + +++ WI T+ Sbjct: 348 TCGQISLPGLYTNVG-EYVQWITDTM 372 >1PQ7-A nrPDB Length = 224 Score = 91.7 bits (226), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 69/220 (31%), Positives = 98/220 (44%), Gaps = 15/220 (6%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHC---NLNKRSQVILGAHSI 85 I+GG + P++V +S + C G+L+ + VLTAAHC Q+ G+ S Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQIRAGSLSR 60 Query: 86 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 T T + V+ +P Y + DL +L+L + L G D G Sbjct: 61 TSGGITSSLSSVRV---HPSY--SGNNNDLAILKLSTSIPSGGNIGYARLAASGSDPVAG 115 Query: 146 TMCQVAGWGRTHNSASWSD-TLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 204 + VAGWG T S + L +V + I+ R C R Y + + M CAG GG Sbjct: 116 SSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATC--RAQYGTSAIT-NQMFCAGVSSGG 172 Query: 205 RDSCNGDSGSPLL-CEGVFRGVTSFGLENKCGDPRGPGVY 243 +DSC GDSG P++ G S+G N C P GVY Sbjct: 173 KDSCQGDSGGPIVDSSNTLIGAVSWG--NGCARPNYSGVY 210 >3F6U-H nrPDB Length = 240 Score = 91.3 bits (225), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 71/243 (29%), Positives = 119/243 (48%), Gaps = 26/243 (10%) Query: 29 IIGGNEVTPHSRPY-MVLLSLDRKTICAGALIAKDWVLTAAHC-NLNKRSQVILGAHSIT 86 +I G P+ +VLL +K C LI WVLTAAHC + +K+ V LG + + Sbjct: 1 LIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLR 60 Query: 87 REEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKG----DDV 142 R E + + +K+ F +P Y +T + D+ LL L + A +++ + + LP G + Sbjct: 61 RWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERELN 120 Query: 143 KPGTMCQVAGWGRTHNSASWSDTLRE-------VNITIIDRKVCNDRNHYNFNPVIGMNM 195 + G V GWG ++S+ + R + I ++ C++ + ++ NM Sbjct: 121 QAGQETLVTGWG--YHSSREKEAKRNRTFVLNFIKIPVVPHNECSEV----MSNMVSENM 174 Query: 196 VCAGSLRGGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHL 251 +CAG L +D+C GDSG P++ G+ S+G CG GVY +S ++L Sbjct: 175 LCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWG--EGCGLLHNYGVYTKVS-RYL 231 Query: 252 NWI 254 +WI Sbjct: 232 DWI 234 >1SI5-H nrPDB Length = 240 Score = 90.9 bits (224), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 72/230 (31%), Positives = 113/230 (49%), Gaps = 24/230 (10%) Query: 42 YMVLLSLDRKTICAGALIAKDWVLTAAHCNLN---KRSQVILGAHSI--TREEPTKQIML 96 +MV L K IC G+LI + WVLTA C + K + LG H + +E KQ++ Sbjct: 13 WMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHDVHGRGDEKCKQVLN 72 Query: 97 VKKEFPYPCYDPATREG-DLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGR 155 V + Y P EG DL L++L A ++ +V+ + LP G + T C V GWG Sbjct: 73 VSQLV----YGP---EGSDLVLMKLARPAVLDDFVSTIDLPNYGSTIPEKTSCSVYGWGY 125 Query: 156 THNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSP 215 T ++ LR ++ I+ + C+ H+ + + +CAG+ + G C GD G P Sbjct: 126 T-GLINYDGLLRVAHLYIMGNEKCS--QHHRGKVTLNESEICAGAEKIGSGPCEGDYGGP 182 Query: 216 LLCEG----VFRGVTSFGLENKCGDPRGPGVYILLS--KKHLNWIIMTIK 259 L+CE + GV G C P PG+++ ++ K ++ II+T K Sbjct: 183 LVCEQHKMRMVLGVIVPG--RGCAIPNRPGIFVRVAYYAKWIHKIILTYK 230 >2JET-B nrPDB Length = 128 Score = 89.7 bits (221), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 46/128 (35%), Positives = 70/128 (54%), Gaps = 5/128 (3%) Query: 32 GNEVTPHSRPYMVLLSLDRKT---ICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 G + P S P+ V SL KT C G+LI++DWV+TAAHC + V+ G + Sbjct: 1 GEDAIPGSWPWQV--SLQDKTGFHFCGGSLISEDWVVTAAHCGVKTSDVVVAGEFDQGSD 58 Query: 89 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMC 148 E Q++ + + F P ++ T D+ LL+L A+ ++ V+ + LP DD PGT+C Sbjct: 59 EENIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDFPPGTVC 118 Query: 149 QVAGWGRT 156 GWG+T Sbjct: 119 ATTGWGKT 126 >1KIG-H nrPDB Length = 241 Score = 88.6 bits (218), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 70/241 (29%), Positives = 110/241 (45%), Gaps = 18/241 (7%) Query: 29 IIGGNEVTPHSRPYMVLL-SLDRKTICAGALIAKDWVLTAAHC-NLNKRSQVILGAHSIT 86 I+GG + P+ LL + + + C G ++ + +VLTAAHC + KR V +G + Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAKRFTVRVGDRNTE 60 Query: 87 REEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGT 146 +EE + V+ + + T + D+ +L+L + + V LP+K D + Sbjct: 61 QEEGNEMAHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEK-DWAEATL 119 Query: 147 MCQ----VAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 202 M Q V+G+GRTH S TL+ + + +DR C + + P NM CAG Sbjct: 120 MTQKTGIVSGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITP----NMFCAGYDT 175 Query: 203 GGRDSCNGDSGSPLLCEG----VFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 D+C GDSG P + G+ S+G C GVY +S L WI + Sbjct: 176 QPEDACQGDSGGPHVTRFKDTYFVTGIVSWG--EGCARKGKFGVYTKVS-NFLKWIDKIM 232 Query: 259 K 259 K Sbjct: 233 K 233 >1BDA-A nrPDB Length = 265 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 74/252 (29%), Positives = 116/252 (46%), Gaps = 30/252 (11%) Query: 28 KIIGGNEVTPHSRPYMVLL------SLDRKTICAGALIAKDWVLTAAHCNLNK----RSQ 77 +I GG S P+ + S + +C G LI+ W+L+AAHC + Sbjct: 13 RIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLT 72 Query: 78 VILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEK----AKINKYVTIL 133 VILG +Q V+K + +D T + D+ LLQL A+ + V + Sbjct: 73 VILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTV 132 Query: 134 HLPKKGDDVKPGTMCQVAGWGRTHN-SASWSDTLREVNITIIDRKVCNDRNHYNFNPVIG 192 LP + T C+++G+G+ S +S+ L+E ++ + C + + N + Sbjct: 133 CLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCT--SQHLLNRTVT 190 Query: 193 MNMVCAGSLRGG------RDSCNGDSGSPLLCEGVFR----GVTSFGLENKCGDPRGPGV 242 NM+CAG R G D+C GDSG PL+C R G+ S+GL CG PGV Sbjct: 191 DNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGL--GCGQKDVPGV 248 Query: 243 YILLSKKHLNWI 254 Y ++ +L+WI Sbjct: 249 YTKVT-NYLDWI 259 >2OLG-A nrPDB Length = 278 Score = 85.1 bits (209), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 69/275 (25%), Positives = 124/275 (45%), Gaps = 41/275 (14%) Query: 20 LIPEDV-----CEKIIGGNEVTPHSRPYMVLLSLDRKT-----ICAGALIAKDWVLTAAH 69 L+P D +KI+ G++ P P+ ++ + C G+LI +++TAAH Sbjct: 9 LLPNDCGYQVEADKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAH 68 Query: 70 CNLNKRSQVILGAHSITREE-----------------PTKQIML-VKKEFPYPCYDPAT- 110 C + +V+ + + E P K I L +++ +P Y + Sbjct: 69 CVAGRVLRVVGALNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVDGSK 128 Query: 111 -REGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREV 169 R D+ L++L + + Y+ + LP+ ++V+ G V GWGRT + +S +++ Sbjct: 129 DRYHDIALIRLNRQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRTE-TGQYSTIKQKL 187 Query: 170 NITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGV-----FRG 224 + ++ + C + + + +CAG + +DSC GDSG PLL E G Sbjct: 188 AVPVVHAEQCA-KTFGAAGVRVRSSQLCAGGEK-AKDSCGGDSGGPLLAERANQQFFLEG 245 Query: 225 VTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 + SFG CG PG+Y + K+ +WI I+ Sbjct: 246 LVSFGA--TCGTEGWPGIYTKVG-KYRDWIEGNIR 277 >5XW8-A nrPDB Length = 133 Score = 84.0 bits (206), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 48/136 (35%), Positives = 70/136 (51%), Gaps = 4/136 (2%) Query: 21 IPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVIL 80 P D +KI+GG +S PY V L+ C G+LI WV++AAHC R QV L Sbjct: 1 FPTDDDDKIVGGYTCAANSIPYQVSLN-SGSHFCGGSLINSQWVVSAAHC-YKSRIQVRL 58 Query: 81 GAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGD 140 G H+I E +Q + K +P ++ T + D+ L++L A +N V + LP+ Sbjct: 59 GEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSC- 117 Query: 141 DVKPGTMCQVAGWGRT 156 GT C ++GWG T Sbjct: 118 -AAAGTECLISGWGNT 132 >1SC8-U nrPDB Length = 262 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 65/247 (26%), Positives = 114/247 (46%), Gaps = 25/247 (10%) Query: 28 KIIGGNEVTPHSRPYMVLLSLDRK-----TICAGALIAKDWVLTAAHCNLNKRSQ----V 78 KIIGG T ++P+ + + +C G+LI+ WV++A HC ++ + V Sbjct: 15 KIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIV 74 Query: 79 ILGAHSITREEPTKQIMLVKKEFPYPCY--DPATREGDLKLLQLMEK----AKINKYVTI 132 LG + + V+ + Y D D+ LL++ K A+ ++ + Sbjct: 75 YLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQT 134 Query: 133 LHLPKKGDDVKPGTMCQVAGWGRTHNSAS-WSDTLREVNITIIDRKVCNDRNHYNFNPVI 191 + LP +D + GT C++ G+G+ +++ + + L+ + +I + C ++Y + Sbjct: 135 ISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSE--V 192 Query: 192 GMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFR----GVTSFGLENKCGDPRGPGVYILLS 247 M+CA + DSC GDSG PL+C R G+ S+G C PGVY +S Sbjct: 193 TTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWG--RGCALKDKPGVYTRVS 250 Query: 248 KKHLNWI 254 L WI Sbjct: 251 -HFLPWI 256 >4KKD-A nrPDB Length = 433 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 68/266 (25%), Positives = 119/266 (44%), Gaps = 40/266 (15%) Query: 27 EKIIGGNEVTPHSRPYMVLLSLDR-------KTICAGALIAKDWVLTAAHCNLNKRSQ-- 77 ++IIGG P P+ L+ ++ K +GAL++ W+LTAAH ++R Sbjct: 153 QRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTT 212 Query: 78 ----------VILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKIN 127 V LG H + R++ + +P ++ D+ L+QL E + Sbjct: 213 VIPVSKEHVTVYLGLHDV-RDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLG 271 Query: 128 KYVTILHLPK-KGDDVKPGTMCQVAGWGRTH-----------NSASWSDTLREVNITIID 175 +V + LP+ + + P + VAGWG ++ + + SD L+ V + ++ Sbjct: 272 PHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVP 331 Query: 176 RKVC-NDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLC------EGVFRGVTSF 228 C + N + NM CAG GG+D+C GDSG + V +G+ S+ Sbjct: 332 HAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGEAFVIFDDLSQRWVVQGLVSW 391 Query: 229 GLENKCGDPRGPGVYILLSKKHLNWI 254 G +CG + GVY +S +++W+ Sbjct: 392 GGPEECGSKQVYGVYTKVS-NYVDWV 416 >1C5M-D nrPDB Length = 255 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 66/241 (27%), Positives = 111/241 (46%), Gaps = 18/241 (7%) Query: 29 IIGGNEVTPHSRPYMVLL-SLDRKTICAGALIAKDWVLTAAHCNLN-KRSQVILGAHSIT 86 I+GG E P+ LL + + + C G ++++ ++LTAAHC KR +V +G + Sbjct: 1 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTE 60 Query: 87 REEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGT 146 +EE + + V+ + + T + D+ +L+L V LP++ D + Sbjct: 61 QEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPER-DWAESTL 119 Query: 147 MCQ----VAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 202 M Q V+G+GRTH S L+ + + +DR C + + +I NM CAG Sbjct: 120 MTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSF----IITQNMFCAGYDT 175 Query: 203 GGRDSCNGDSGSPLLCEG----VFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 D+C GDSG P + G+ S+G C G+Y ++ L WI ++ Sbjct: 176 KQEDACQGDSGGPHVTRFKDTYFVTGIVSWG--EGCARKGKYGIYTKVT-AFLKWIDRSM 232 Query: 259 K 259 K Sbjct: 233 K 233 >1Q3X-A nrPDB Length = 328 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 74/241 (30%), Positives = 114/241 (47%), Gaps = 19/241 (7%) Query: 28 KIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKR---SQVILGAHS 84 +I GG + P P+ VL+ T AGAL+ +WVLTAAH ++ S + + + Sbjct: 86 RIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGT 143 Query: 85 ITREEPTKQIMLVKKEFPYPCYD-PATREGDLKLLQLMEKAKINKYVTILHLPKKGDD-- 141 + R P + F + Y A + D+ L++L K IN +T + LP+K + Sbjct: 144 LKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAESF 203 Query: 142 VKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNP--VIGMNMVCAG 199 ++ + +GWG T + L V+I I+D + C P + NM+CAG Sbjct: 204 MRTDDIGTASGWGLTQR-GFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANMLCAG 262 Query: 200 SLRGGRDSCNGDSGSPLL-----CEGVF-RGVTSFGLENKCGDPRGPGVYILLSKKHLNW 253 GG+DSC GDSG L+ E F G+ S+G N CG+ GVY + ++ W Sbjct: 263 LESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMN-CGEAGQYGVYTKV-INYIPW 320 Query: 254 I 254 I Sbjct: 321 I 321 >3VGC-B nrPDB Length = 131 Score = 82.8 bits (203), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 46/131 (35%), Positives = 63/131 (48%), Gaps = 5/131 (3%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKT---ICAGALIAKDWVLTAAHCNLNKRSQVILGAHSI 85 I+ G E P S P+ V SL KT C G+LI ++WV+TAAHC + V+ G Sbjct: 1 IVNGEEAVPGSWPWQV--SLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQ 58 Query: 86 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 Q + + K F Y+ T D+ LL+L A ++ V+ + LP DD G Sbjct: 59 GSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAAG 118 Query: 146 TMCQVAGWGRT 156 T C GWG T Sbjct: 119 TTCVTTGWGLT 129 >1ZJK-A nrPDB Length = 403 Score = 82.0 bits (201), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 74/241 (30%), Positives = 114/241 (47%), Gaps = 19/241 (7%) Query: 28 KIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKR---SQVILGAHS 84 +I GG + P P+ VL+ T AGAL+ +WVLTAAH ++ S + + + Sbjct: 161 QIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGT 218 Query: 85 ITREEPTKQIMLVKKEFPYPCY-DPATREGDLKLLQLMEKAKINKYVTILHLPKKGDD-- 141 + R P + F + Y A + D+ L++L K IN +T + LP+K + Sbjct: 219 LKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAESF 278 Query: 142 VKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNP--VIGMNMVCAG 199 ++ + +GWG T + L V+I I+D + C P + NM+CAG Sbjct: 279 MRTDDIGTASGWGLTQR-GFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANMLCAG 337 Query: 200 SLRGGRDSCNGDSGSPLL-----CEGVF-RGVTSFGLENKCGDPRGPGVYILLSKKHLNW 253 GG+DSC GDSG L+ E F G+ S+G N CG+ GVY + ++ W Sbjct: 338 LESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMN-CGEAGQYGVYTKV-INYIPW 395 Query: 254 I 254 I Sbjct: 396 I 396 >4IW4-E nrPDB Length = 279 Score = 82.0 bits (201), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 68/264 (25%), Positives = 117/264 (44%), Gaps = 40/264 (15%) Query: 29 IIGGNEVTPHSRPYMVLLSLDR-------KTICAGALIAKDWVLTAAHCNLNKRSQ---- 77 IIGG P P+ L+ ++ K +GAL++ W+LTAAH ++R Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 78 --------VILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKY 129 V LG H + R++ + +P ++ D+ L+QL E + + Sbjct: 61 PVSKEHVTVYLGLHDV-RDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPH 119 Query: 130 VTILHLPK-KGDDVKPGTMCQVAGWGRTH-----------NSASWSDTLREVNITIIDRK 177 V + LP+ + + P + VAGWG ++ + + SD L+ V + ++ Sbjct: 120 VMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHA 179 Query: 178 VC-NDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLC------EGVFRGVTSFGL 230 C + N + NM CAG GG+D+C GDSG + V +G+ S+G Sbjct: 180 ECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWGG 239 Query: 231 ENKCGDPRGPGVYILLSKKHLNWI 254 +CG + GVY +S +++W+ Sbjct: 240 PEECGSKQVYGVYTKVS-NYVDWV 262 >4FXG-H nrPDB Length = 242 Score = 81.6 bits (200), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 71/229 (31%), Positives = 108/229 (47%), Gaps = 18/229 (7%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKR---SQVILGAHSI 85 I GG + P P+ VL+ T AGAL+ +WVLTAAH ++ S + + ++ Sbjct: 1 IYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGTL 58 Query: 86 TREEPTKQIMLVKKEFPYPCY-DPATREGDLKLLQLMEKAKINKYVTILHLPKKGDD--V 142 R P + F + Y A + D+ L++L K IN +T + LP+K + + Sbjct: 59 KRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAESFM 118 Query: 143 KPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNP--VIGMNMVCAGS 200 + + +GWG T + L V+I I+D + C P + NM+CAG Sbjct: 119 RTDDIGTASGWGLTQRGFL-ARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANMLCAGL 177 Query: 201 LRGGRDSCNGDSGSPLL-----CEGVF-RGVTSFGLENKCGDPRGPGVY 243 GG+DSC GD+G L+ E F G+ S+G N CG+ GVY Sbjct: 178 ESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMN-CGEAGQYGVY 225 >1YM0-A nrPDB Length = 238 Score = 80.9 bits (198), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 73/245 (29%), Positives = 108/245 (44%), Gaps = 25/245 (10%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKT----ICAGALIAKDWVLTAAHCNLNKRS---QVILG 81 I+GG E P+ P+ V S+ RK+ C G++I WV+ AAHC + +++G Sbjct: 1 IVGGIEARPYEFPWQV--SVRRKSSDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVG 58 Query: 82 AHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDD 141 H + +Q V F YDPAT E D+ +++ + V + P +D Sbjct: 59 EHDSSAASTVRQTHDVDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICAPDPAND 118 Query: 142 VKPGTMCQVAGWGRTHNSA-SWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGS 200 Q +GWG ++ LR V + I C + + I +M+CA Sbjct: 119 YVY-RKSQCSGWGTINSGGVCCPAVLRYVTLNITTNAFC---DAVYTSDTIYDDMICATD 174 Query: 201 LRG--GRDSCNGDSGSPLLCE---GVFR--GVTSFGLENKCGDPRGPGVYILLSKKHLNW 253 G RDSC GDSG PL + G+F G+ S+G+ G PGVY + H W Sbjct: 175 NTGMTDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWGIGCASG---YPGVYSRVG-FHAGW 230 Query: 254 IIMTI 258 I TI Sbjct: 231 ITDTI 235 >5LHN-A nrPDB Length = 247 Score = 80.5 bits (197), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 67/247 (27%), Positives = 110/247 (44%), Gaps = 26/247 (10%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRK------TICAGALIAKDWVLTAAHC--NLNKRSQ--V 78 I+GG ++P+ + K C G+LI+ WV +AAHC L K+ V Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 79 ILGAHSITREEPTKQIMLVKKEFPYPCY--DPATREGDLKLLQLMEK----AKINKYVTI 132 LG + P + V++ + Y D D+ LL++ A+ ++ + Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQT 120 Query: 133 LHLPKKGDDVKPGTMCQVAGWGRTHNSAS-WSDTLREVNITIIDRKVCNDRNHYNFNPVI 191 + LP + D G+ C++ G+G+ S + L+ + ++ + C ++Y I Sbjct: 121 IALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQPHYYGSE--I 178 Query: 192 GMNMVCAGSLRGGRDSCNGDSGSPLLC--EG--VFRGVTSFGLENKCGDPRGPGVYILLS 247 M+CA DSC GDSG PL+C EG G+ S+G C + PGVY +S Sbjct: 179 NYKMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWG--RGCAEKNKPGVYTRVS 236 Query: 248 KKHLNWI 254 L+WI Sbjct: 237 -HFLDWI 242 >1EQ9-A nrPDB Length = 222 Score = 80.5 bits (197), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 66/236 (27%), Positives = 110/236 (46%), Gaps = 20/236 (8%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHC-----NLNKRSQVILGAH 83 I+GG + PY V L L C +++ + VLTAAHC NLN R +V +G + Sbjct: 1 IVGGKDAPVGKYPYQVSLRLSGSHRCGASILDNNNVLTAAHCVDGLSNLN-RLKVHVGTN 59 Query: 84 SITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVK 143 ++ + + V+ YD D+ L+ L K N V + L +D++ Sbjct: 60 YLSE---SGDVYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTNDEDLE 116 Query: 144 PGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRG 203 C + GWG T + + L+E+ + + +K C +R+ + + + +C + RG Sbjct: 117 SNP-CTLTGWGSTRLGGNTPNALQEIELIVHPQKQC-ERDQWR----VIDSHICTLTKRG 170 Query: 204 GRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 +C+GDSG PL+ G G+ SFG G+P VY +S ++WI +K Sbjct: 171 -EGACHGDSGGPLVANGAQIGIVSFGSPCALGEPD---VYTRVS-SFVSWINANLK 221 >3H7T-A nrPDB Length = 235 Score = 80.1 bits (196), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 58/204 (28%), Positives = 96/204 (47%), Gaps = 6/204 (2%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHC-NLNKRSQVILGAHSITR 87 IIGG + P+ V + +D K C G+++ ++V+TAA C + K S + + H + Sbjct: 1 IIGGKKSDITKEPWAVGVLVDEKPFCGGSILTANFVITAAQCVDGTKPSDISI--HYGSS 58 Query: 88 EEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVT-ILHLPKKGDDVKPGT 146 TK ++ K+ Y P T + + +++ K++ T + LP D +P T Sbjct: 59 YRTTKGTSVMAKKIYIVRYHPLTMQNNYAVIETEMPIKLDDKTTKKIELPSLLYDPEPDT 118 Query: 147 MCQVAGWGRTH-NSASWSDTLREVNITIIDRKVCNDR-NHYNFNPVIGMNMVCAGSLRGG 204 V+GWG T+ S +S L E N T++DRK C ++ + I + CAG Sbjct: 119 SVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGVFCAGGEYDE 178 Query: 205 RDSCNGDSGSPLLCEGVFRGVTSF 228 GD+G P + G GV S+ Sbjct: 179 TYIGYGDAGDPAVQNGTLVGVASY 202 >4Z6A-H nrPDB Length = 249 Score = 79.7 bits (195), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 65/237 (27%), Positives = 108/237 (45%), Gaps = 18/237 (7%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCN---LNKRSQV-ILGAHS 84 I+GG P+ VLL ++ +C G LI WV++AAHC N R+ + +LG H Sbjct: 1 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHD 60 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKP 144 ++ + +Q V + Y P T D+ LL+L + + +V L LP++ + Sbjct: 61 LSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERT 120 Query: 145 GTMCQ---VAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSL 201 + V+GWG+ + + + L +N+ + + C ++ I M CAG Sbjct: 121 LAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEA----SYPGKITEYMFCAGYS 176 Query: 202 RGGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 G +DSC GDSG P G+ S+G C GVY +S +++ W+ Sbjct: 177 DGSKDSCKGDSGGPHATHYRGTWYLTGIVSWG--QGCATVGHFGVYTRVS-QYIEWL 230 >5O32-I nrPDB Length = 244 Score = 77.8 bits (190), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 69/241 (28%), Positives = 107/241 (44%), Gaps = 26/241 (10%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHC-NLNKRSQVILGAHSITR 87 I+GG P+ V + C G I W+LTAAHC +K + + + Sbjct: 1 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 60 Query: 88 EEPT-KQIML--VKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILH------LPKK 138 P K+I++ V + + Y+ T + D+ L+++ K NK L +P Sbjct: 61 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEM--KKDGNKKDCELPRSIPACVPWS 118 Query: 139 GDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCA 198 +P C V+GWGR D R ++ + K+ ++ + + N M CA Sbjct: 119 PYLFQPNDTCIVSGWGRE------KDNERVFSLQWGEVKLISNCSKFYGNRFYEKEMECA 172 Query: 199 GSLRGGRDSCNGDSGSPLLCEGV-----FRGVTSFGLENKCGDPRGPGVYILLSKKHLNW 253 G+ G D+C GDSG PL+C GV S+G EN CG P PGVY ++ + +W Sbjct: 173 GTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-EN-CGKPEFPGVYTKVA-NYFDW 229 Query: 254 I 254 I Sbjct: 230 I 230 >3NXP-A nrPDB Length = 424 Score = 77.8 bits (190), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 70/256 (27%), Positives = 118/256 (46%), Gaps = 39/256 (15%) Query: 7 FLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLL--SLDRKTICAGALIAKDWV 64 F SL L+ + +I+ G++ P+ V+L ++ +C +LI+ WV Sbjct: 144 FEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWV 203 Query: 65 LTAAHC--------NLNKRSQVI-LGAHSITR-EEPTKQIMLVKKEFPYPCYD-PATREG 113 LTAAHC N + ++ +G HS TR E ++I +++K + +P Y+ + Sbjct: 204 LTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDR 263 Query: 114 DLKLLQLMEKAKINKYVTILHLPKK---GDDVKPGTMCQVAGWGRTHNSASWS------- 163 D+ L++L + + Y+ + LP + ++ G +V GWG +W+ Sbjct: 264 DIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKE--TWTANVGKGQ 321 Query: 164 -DTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSL--RGGR-DSCNGDSGSPLLCE 219 L+ VN+ I++R VC D I NM CAG G R D+C GDSG P + + Sbjct: 322 PSVLQVVNLPIVERPVCKDSTRIR----ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMK 377 Query: 220 GVFR------GVTSFG 229 F G+ S+G Sbjct: 378 SPFNNRWYQMGIVSWG 393 >6BQM-A nrPDB Length = 506 Score = 77.4 bits (189), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 68/240 (28%), Positives = 108/240 (45%), Gaps = 23/240 (9%) Query: 25 VCEKIIGGNEVTPHSRPYMVLLSLDRKT--ICAGALIAKDWVLTAAHCNLNK----RSQV 78 V +IIGG + T PYMV L+ + C G+ + +VLTAAHC ++K + V Sbjct: 7 VSSRIIGGEQATAGEWPYMVALTARNSSHVFCGGSYLGGRYVLTAAHC-VDKEDPAKGDV 65 Query: 79 ILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKK 138 +LGA + ++I V++ + + Y A+ D+ +L+L + V I Sbjct: 66 LLGAFDMNDVNTAERIH-VRQIYVHNSYITASMGNDIAVLELERDPLPRRSVQISDSSDF 124 Query: 139 GDDVKPGTMCQVAGWGRTHNSASWSD---TLREVNITIIDRKVC----NDRNHYNFNPVI 191 + K M + R SD L +V + + C +D++ N + Sbjct: 125 NELTKDSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGSDQDAKNNYSQL 184 Query: 192 GMNMVCAGSLRGGRDSCNGDSGSPLLCEG----VFRGVTSFGLENKCGDPRGPGVYILLS 247 N CAGS G+D+C+GD+G P+ + GV S+G + CG PGVY LS Sbjct: 185 TNNAFCAGSF--GKDACSGDAGGPIFFDSNNGRKQMGVVSWG--DGCGRANSPGVYTNLS 240 >3K65-B nrPDB Length = 308 Score = 77.4 bits (189), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 69/256 (26%), Positives = 118/256 (46%), Gaps = 39/256 (15%) Query: 7 FLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLL--SLDRKTICAGALIAKDWV 64 F SL L+ + +I+ G++ P+ V+L ++ +C +LI+ WV Sbjct: 28 FEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWV 87 Query: 65 LTAAHC--------NLNKRSQVI-LGAHSITR-EEPTKQIMLVKKEFPYPCYD-PATREG 113 LTAAHC N + ++ +G HS TR E ++I +++K + +P Y+ + Sbjct: 88 LTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDR 147 Query: 114 DLKLLQLMEKAKINKYVTILHLPKK---GDDVKPGTMCQVAGWGRTHNSASWS------- 163 D+ L++L + + Y+ + LP + ++ G +V GWG +W+ Sbjct: 148 DIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKE--TWTANVGKGQ 205 Query: 164 -DTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSL--RGGR-DSCNGDSGSPLLCE 219 L+ VN+ I++R VC D I NM CAG G R D+C GD+G P + + Sbjct: 206 PSVLQVVNLPIVERPVCKDSTRIR----ITDNMFCAGYKPDEGKRGDACEGDAGGPFVMK 261 Query: 220 GVFR------GVTSFG 229 F G+ S+G Sbjct: 262 SPFNNRWYQMGIVSWG 277 >2B9L-A nrPDB Length = 394 Score = 77.4 bits (189), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 70/251 (27%), Positives = 113/251 (45%), Gaps = 36/251 (14%) Query: 33 NEVTPHSRPYMVLL--------SLDRKTICAGALIAKDWVLTAAHCNLNKRSQV----IL 80 NE P+MV + S + + +C G+LIA VLT AHC + +S + I Sbjct: 135 NEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHCVNSYQSNLDAIKIR 194 Query: 81 GAHSITREEPTK---QIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPK 137 T E + Q +++ + ++P T D+ LL L + + LP+ Sbjct: 195 AGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLLDRPLVQADNIGTICLPQ 254 Query: 138 KGDDVKPGTMCQVAGWGRTHNSAS--WSDTLREVNITIIDRKVC-----NDRNHYNFNPV 190 + + T C +GWG+ + +S+ L+++ + +DR C N R F V Sbjct: 255 Q-SQIFDSTECFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQADLRNTRLGLKF--V 311 Query: 191 IGMNMVCAGSLRGGRDSCNGDSGSPLLCEG-------VFRGVTSFGLENKCGDPRGPGVY 243 + VCAG +G +D+C GD GSPL C + G+ ++G+ CGD PGVY Sbjct: 312 LDQTFVCAGGEQG-KDTCTGDGGSPLFCPDPRNPSRYMQMGIVAWGI--GCGDENVPGVY 368 Query: 244 ILLSKKHLNWI 254 ++ NWI Sbjct: 369 ANVA-HFRNWI 378 >2XRC-A nrPDB Length = 565 Score = 77.0 bits (188), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 69/243 (28%), Positives = 109/243 (44%), Gaps = 26/243 (10%) Query: 27 EKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHC-NLNKRSQVILGAHSI 85 ++I+GG P+ V + C G I W+LTAAHC +K + + + Sbjct: 320 KRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVV 379 Query: 86 TREEPT-KQIML--VKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILH------LP 136 P K+I++ V + + Y+ T + D+ L+++ K NK L +P Sbjct: 380 DWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEM--KKDGNKKDCELPRSIPACVP 437 Query: 137 KKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMV 196 +P C V+GWGR D R ++ + K+ ++ + + N M Sbjct: 438 WSPYLFQPNDTCIVSGWGRE------KDNERVFSLQWGEVKLISNCSKFYGNRFYEKEME 491 Query: 197 CAGSLRGGRDSCNGDSGSPLLCEGV-----FRGVTSFGLENKCGDPRGPGVYILLSKKHL 251 CAG+ G D+C GDSG PL+C GV S+G EN CG P PGVY ++ + Sbjct: 492 CAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-EN-CGKPEFPGVYTKVA-NYF 548 Query: 252 NWI 254 +WI Sbjct: 549 DWI 551 >4NZQ-A nrPDB Length = 557 Score = 77.0 bits (188), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 70/256 (27%), Positives = 118/256 (46%), Gaps = 39/256 (15%) Query: 7 FLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLL--SLDRKTICAGALIAKDWV 64 F SL L+ + +I+ G++ P+ V+L ++ +C +LI+ WV Sbjct: 277 FEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWV 336 Query: 65 LTAAHC--------NLNKRSQVI-LGAHSITR-EEPTKQIMLVKKEFPYPCYD-PATREG 113 LTAAHC N + ++ +G HS TR E ++I +++K + +P Y+ + Sbjct: 337 LTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDR 396 Query: 114 DLKLLQLMEKAKINKYVTILHLPKK---GDDVKPGTMCQVAGWGRTHNSASWS------- 163 D+ L++L + + Y+ + LP + ++ G +V GWG +W+ Sbjct: 397 DIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKE--TWTANVGKGQ 454 Query: 164 -DTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSL--RGGR-DSCNGDSGSPLLCE 219 L+ VN+ I++R VC D I NM CAG G R D+C GDSG P + + Sbjct: 455 PSVLQVVNLPIVERPVCKDSTRIR----ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMK 510 Query: 220 GVFR------GVTSFG 229 F G+ S+G Sbjct: 511 SPFNNRWYQMGIVSWG 526 >1MKW-K nrPDB Length = 308 Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 67/235 (28%), Positives = 110/235 (46%), Gaps = 39/235 (16%) Query: 28 KIIGGNEVTPHSRPYMVLL--SLDRKTICAGALIAKDWVLTAAHCNLNKRSQ-------- 77 +I+ G + P+ V+L ++ +C +LI+ WVLTAAHC L Sbjct: 49 RIVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDL 108 Query: 78 -VILGAHSITR-EEPTKQIMLVKKEFPYPCYD-PATREGDLKLLQLMEKAKINKYVTILH 134 V +G HS TR E ++I ++ K + +P Y+ + D+ LL+L +++ Y+ + Sbjct: 109 LVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVC 168 Query: 135 LPKKGDDVK---PGTMCQVAGWGRTHNSASWSDTLRE--------VNITIIDRKVCNDRN 183 LP K K G +V GWG + +W+ ++ E VN+ +++R VC Sbjct: 169 LPDKQTAAKLLHAGFKGRVTGWG--NRRETWTTSVAEVQPSVLQVVNLPLVERPVCKAST 226 Query: 184 HYNFNPVIGMNMVCAGSLRG-GR--DSCNGDSGSPLLCEGVFR------GVTSFG 229 I NM CAG G G+ D+C GDSG P + + + G+ S+G Sbjct: 227 RIR----ITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWG 277 >3I77-A nrPDB Length = 230 Score = 75.5 bits (184), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 64/228 (28%), Positives = 98/228 (42%), Gaps = 20/228 (8%) Query: 29 IIGGNEVTPHSRPYMV-LLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITR 87 ++GG P+MV L++ + + C GAL A+D VLTAAHC + + A Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEGFCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVV 60 Query: 88 EEPTKQIMLVK--KEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 + + + V+ K P + T D L++L + IN+ + G Sbjct: 61 DLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQ--PINQPTLKIATTTA---YNQG 115 Query: 146 TMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSL-RGG 204 T VAGWG S L + N+ + C + + ++ M+CAG GG Sbjct: 116 TFT-VAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSF---ILVANEMICAGYPDTGG 171 Query: 205 RDSCNGDSGSPLL-----CEGVFRGVTSFGLENKCGDPRGPGVYILLS 247 D+C GDSG P+ E + G+ S+G C P PGVY +S Sbjct: 172 VDTCQGDSGGPMFRKDNADEWIQVGIVSWGY--GCARPGYPGVYTEVS 217 >2OCV-B nrPDB Length = 259 Score = 75.5 bits (184), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 67/236 (28%), Positives = 110/236 (46%), Gaps = 43/236 (18%) Query: 29 IIGGNEVTPHSRPYMVLL--SLDRKTICAGALIAKDWVLTAAHC--------NLNKRSQV 78 I+ G + P+ V+L ++ +C +LI+ WVLTAAHC N + + Sbjct: 1 IVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLL 60 Query: 79 I-LGAHSITR-EEPTKQIMLVKKEFPYPCYD-PATREGDLKLLQLMEKAKINKYVTILHL 135 + +G HS TR E ++I +++K + +P Y+ + D+ LL+L + + Y+ + L Sbjct: 61 VRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCL 120 Query: 136 PKKG---DDVKPGTMCQVAGWGRTHNSASWSDTLRE--------VNITIIDRKVCNDRNH 184 P K ++ G +V GWG +W+ + E VN+ I++R VC Sbjct: 121 PDKQTVTSLLRAGYKGRVTGWGNLRE--TWTTNINEIQPSVLQVVNLPIVERPVCKASTR 178 Query: 185 YNFNPVIGMNMVCAG-----SLRGGRDSCNGDSGSPLLCEGVFR------GVTSFG 229 I NM CAG + RG D+C GDSG P + + F G+ S+G Sbjct: 179 IR----ITDNMFCAGFKVNDTKRG--DACEGDSGGPFVMKSPFNNRWYQMGIVSWG 228 >1ETT-H nrPDB Length = 259 Score = 75.1 bits (183), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 67/234 (28%), Positives = 109/234 (46%), Gaps = 39/234 (16%) Query: 29 IIGGNEVTPHSRPYMVLL--SLDRKTICAGALIAKDWVLTAAHCNLNKRSQ--------- 77 I+ G + P+ V+L ++ +C +LI+ WVLTAAHC L Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 78 VILGAHSITR-EEPTKQIMLVKKEFPYPCYD-PATREGDLKLLQLMEKAKINKYVTILHL 135 V +G HS TR E ++I ++ K + +P Y+ + D+ LL+L +++ Y+ + L Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCL 120 Query: 136 PKKGDDVK---PGTMCQVAGWGRTHNSASWSDTLRE--------VNITIIDRKVCNDRNH 184 P K K G +V GWG + +W+ ++ E VN+ +++R VC Sbjct: 121 PDKQTAAKLLHAGFKGRVTGWG--NRRETWTTSVAEVQPSVLQVVNLPLVERPVCKASTR 178 Query: 185 YNFNPVIGMNMVCAGSLRG-GR--DSCNGDSGSPLLCEGVFR------GVTSFG 229 I NM CAG G G+ D+C GDSG P + + + G+ S+G Sbjct: 179 IR----ITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWG 228 >5TO3-B nrPDB Length = 409 Score = 73.6 bits (179), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 63/221 (28%), Positives = 106/221 (47%), Gaps = 33/221 (14%) Query: 29 IIGGNEVTPHSRPYMVLL--SLDRKTICAGALIAKDWVLTAAHC--------NLNKRSQV 78 I+ G++ P+ V+L ++ +C +LI+ WVLTAAHC N + + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 79 I-LGAHSITR-EEPTKQIMLVKKEFPYPCYD-PATREGDLKLLQLMEKAKINKYVTILHL 135 + +G HS TR E ++I +++K + +P Y+ + D+ L++L + + Y+ + L Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL 120 Query: 136 PKK---GDDVKPGTMCQVAGWGRTHNSASWS--------DTLREVNITIIDRKVCNDRNH 184 P + ++ G +V GWG +W+ L+ VN+ I++R VC D Sbjct: 121 PDRETAASLLQAGYKGRVTGWGNLKE--TWTANVGKGQPSVLQVVNLPIVERPVCKDSTR 178 Query: 185 YNFNPVIGMNMVCAGSL--RGGR-DSCNGDSGSPLLCEGVF 222 I NM CAG G R D+C GDSG P + + F Sbjct: 179 IR----ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPF 215 >1ELV-A nrPDB Length = 333 Score = 73.2 bits (178), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 76/282 (26%), Positives = 124/282 (43%), Gaps = 45/282 (15%) Query: 8 LASSLSVVVSLLLIPEDVCE---KIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWV 64 L L V + +P + E +IIGG++ + P+ V GALI + WV Sbjct: 59 LGPELPKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFD---NPWAGGALINEYWV 115 Query: 65 LTAAH-CNLNKRSQVILGAHSITREEPTKQIMLVKKE-FPYPCYD----PATR---EGDL 115 LTAAH N+ + +G+ S+ K ML + F +P + P R + D+ Sbjct: 116 LTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLAVPEGRTNFDNDI 175 Query: 116 KLLQLMEKAKINKYVTILHLPKKGDD--VKPGTMCQVAGWGRTHNSASWSDTLREVNITI 173 L++L + K+ V+ + LP D + G + ++GWGRT + L+ + + Sbjct: 176 ALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPV 234 Query: 174 IDRKVCN---------DRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEG---- 220 + C D Y F P NM+CAG + G DSC GDSG + Sbjct: 235 APLRKCKEVKVEKPTADAEAYVFTP----NMICAGGEK-GMDSCKGDSGGAFAVQDPNDK 289 Query: 221 ---VFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 G+ S+G + CG G+Y + K +++WI+ T++ Sbjct: 290 TKFYAAGLVSWGPQ--CGT---YGLYTRV-KNYVDWIMKTMQ 325 >1VR1-H nrPDB Length = 261 Score = 73.2 bits (178), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 66/238 (27%), Positives = 110/238 (46%), Gaps = 43/238 (18%) Query: 29 IIGGNEVTPHSRPYMVLL------SLDRKTICAGALIAKDWVLTAAHC--------NLNK 74 I+ G++ P+ V+L S + +C +LI+ WVLTAAHC N + Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 75 RSQVI-LGAHSITR-EEPTKQIMLVKKEFPYPCYD-PATREGDLKLLQLMEKAKINKYVT 131 ++ +G HS TR E ++I +++K + +P Y+ + D+ L++L + + Y+ Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 120 Query: 132 ILHLPKK---GDDVKPGTMCQVAGWGRTHNSASWS--------DTLREVNITIIDRKVCN 180 + LP + ++ G +V GWG +W+ L+ VN+ I++R VC Sbjct: 121 PVCLPDRETAASLLQAGYKGRVTGWGNL--KETWTANVGKGQPSVLQVVNLPIVERPVCK 178 Query: 181 DRNHYNFNPVIGMNMVCA--GSLRGGR-DSCNGDSGSPLLCEGVFR------GVTSFG 229 D I NM CA G R D+C GDSG P + + F G+ S+G Sbjct: 179 DSTRIR----ITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG 232 >5UBM-A nrPDB Length = 252 Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 71/259 (27%), Positives = 116/259 (44%), Gaps = 42/259 (16%) Query: 28 KIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAH-CNLNKRSQVILGAHSIT 86 +IIGG++ + P+ V GALI + WVLTAAH N+ + +G+ S+ Sbjct: 1 RIIGGSDADIKNFPWQVFFD---NPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQ 57 Query: 87 REEPTKQIMLVKKE-FPYPCYD----PATR---EGDLKLLQLMEKAKINKYVTILHLPKK 138 K ML + F +P + P R + D+ L++L + K+ V+ + LP Sbjct: 58 TSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGT 117 Query: 139 GDD--VKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCN---------DRNHYNF 187 D + G + ++GWGRT + L+ + + + C D Y F Sbjct: 118 SSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPVAPLRKCKEVKVEKPTADAEAYVF 176 Query: 188 NPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEG-------VFRGVTSFGLENKCGDPRGP 240 P NM+CAG + G DSC GDSG + G+ S+G + CG Sbjct: 177 TP----NMICAGGEK-GMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQ--CGT---Y 226 Query: 241 GVYILLSKKHLNWIIMTIK 259 G+Y + K +++WI+ T++ Sbjct: 227 GLYTRV-KNYVDWIMKTMQ 244 >2FMJ-A nrPDB Length = 222 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 56/192 (29%), Positives = 83/192 (43%), Gaps = 19/192 (9%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 ++GG P+MV LS+ C GAL A+D VLTAAHC + + A + Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG----CGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 89 EPTKQIMLVK--KEFPYPCYDPATREGDL-KLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 + + V+ K P Y+ ++ L KL Q + + + T + G Sbjct: 57 LQSSSAVKVRSTKVLQAPGYNGTGKDWALIKLAQPINQPTLKIATTTAY--------NQG 108 Query: 146 TMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 205 T VAGWG S L + N+ + C R+ Y N ++ +CAG GG Sbjct: 109 TFT-VAGWGANREGGSQQRYLLKANVPFVSDAAC--RSAYG-NELVANEEICAGYDTGGV 164 Query: 206 DSCNGDSGSPLL 217 D+C GDSG P+ Sbjct: 165 DTCQGDSGGPMF 176 >4LK4-A nrPDB Length = 357 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 63/244 (25%), Positives = 110/244 (45%), Gaps = 21/244 (8%) Query: 24 DVCEKIIGGNEVTPHSRPYMVLL-----SLDRKTICAGALIAKDWVLTAAHCNLNKRS-- 76 D+ +II G+ P +V L + C G+ + +VLTAAHC + RS Sbjct: 6 DISSRIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHC-FDSRSAA 64 Query: 77 --QVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILH 134 VI+GA+ + ++I +K + + Y P+ D+ +++L + + + L Sbjct: 65 SVDVIIGAYDLNNSSQGERIA-AQKIYRHLSYSPSNLLNDIAIVELAQTSSLP--AITLA 121 Query: 135 LPKKGDDVKPGTMCQVAGWGRTHNSA--SWSDTLREVNITIIDRKVCNDRNHYNFNPVIG 192 P + T VAGWG T S ++ L+EV++ ++ + +C + + Sbjct: 122 GPATRTSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQHGISSDPN 181 Query: 193 MNMVCAGSLRGGRDSCNGDSGSPLLCEGVFR--GVTSFGLENKCGDPRGPGVYILLSKKH 250 CA L +DSC GD+G P++ + G+ S+G E +C GVY +S Sbjct: 182 STNFCAARLT--KDSCQGDAGGPIVVKTGREQLGIVSWGDE-QCAKTGTYGVYTNVS-YF 237 Query: 251 LNWI 254 +WI Sbjct: 238 RDWI 241 >4J1Y-A nrPDB Length = 397 Score = 71.2 bits (173), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 75/282 (26%), Positives = 123/282 (43%), Gaps = 45/282 (15%) Query: 8 LASSLSVVVSLLLIPEDVCE---KIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWV 64 L L V + +P + E + IGG++ + P+ V GALI + WV Sbjct: 123 LGPELPKCVPVCGVPREPFEEKARAIGGSDADIKNFPWQVFFD---NPWAGGALINEYWV 179 Query: 65 LTAAH-CNLNKRSQVILGAHSITREEPTKQIMLVKKE-FPYPCYD----PATR---EGDL 115 LTAAH N+ + +G+ S+ K ML + F +P + P R + D+ Sbjct: 180 LTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDI 239 Query: 116 KLLQLMEKAKINKYVTILHLPKKGDD--VKPGTMCQVAGWGRTHNSASWSDTLREVNITI 173 L++L + K+ V+ + LP D + G + ++GWGRT + L+ + + Sbjct: 240 ALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPV 298 Query: 174 IDRKVCN---------DRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEG---- 220 + C D Y F P NM+CAG + G DSC GDSG + Sbjct: 299 APLRKCKEVKVEKPTADAEAYVFTP----NMICAGGEK-GMDSCKGDSGGAFAVQDPNDK 353 Query: 221 ---VFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 G+ S+G + CG G+Y + K +++WI+ T++ Sbjct: 354 TKFYAAGLVSWGPQ--CGT---YGLYTRV-KNYVDWIMKTMQ 389 >2ASU-B nrPDB Length = 234 Score = 69.7 bits (169), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 66/240 (27%), Positives = 109/240 (45%), Gaps = 33/240 (13%) Query: 29 IIGGNEVTPHSRPYMV-LLSLDRKTICAGALIAKDWVLTAAHCNLN-----KRSQVILGA 82 ++GG+ P + P+ V L + + C G+L+ + W+LTA C + +V LG Sbjct: 1 VVGGH---PGNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWLGT 57 Query: 83 --HSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGD 140 + EP+ Q + V K P L LL+L +N+ V ++ LP + Sbjct: 58 LFQNPQHGEPSLQRVPVAKMVCGP------SGSQLVLLKLERSVTLNQRVALICLPPEWY 111 Query: 141 DVKPGTMCQVAGWGRTHNSASWSDTLREVN-ITIIDRKVCNDRNHYNFNPVIGMNMVCAG 199 V PGT C++AGWG T + +DT+ V + +I + CN ++ + + +C Sbjct: 112 VVPPGTKCEIAGWGETKGTG--NDTVLNVALLNVISNQECNIKHRGR----VRESEMCTE 165 Query: 200 SLRGGRDSCNGDSGSPLLC----EGVFRGVTSFGLENK-CGDPRGPGVYILLSKKHLNWI 254 L +C GD G PL C V G+ + N+ C R P V+ +S ++WI Sbjct: 166 GLLAPVGACEGDYGGPLACFTHNSWVLEGII---IPNRVCARSRWPAVFTRVS-VFVDWI 221 >4X0L-C nrPDB Length = 259 Score = 68.6 bits (166), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 63/259 (24%), Positives = 112/259 (43%), Gaps = 32/259 (12%) Query: 22 PEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAA---HCNLNKRSQV 78 P + ++I+GG+ S P+ + LI + W+LT A N ++ + Sbjct: 8 PANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATA 67 Query: 79 ILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKK 138 A ++T KQ++ ++K +P Y + D+ L++L +K +N+ V + LP K Sbjct: 68 KDIAPTLTLYVGKKQLVEIEKVVLHPNYS----QVDIGLIKLKQKVSVNERVMPICLPSK 123 Query: 139 GDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYN------------ 186 D + G + V+GWGR N ++D L+ V + + D+ C HY Sbjct: 124 -DYAEVGRVGYVSGWGRNAN-FKFTDHLKYVMLPVADQDQC--IRHYEGSTVPEKKTPKS 179 Query: 187 ---FNPVIGMNMVCAGSLRGGRDSCNGDSGSPL----LCEGVFRGVTSFGLENKCGDPRG 239 P++ + CAG + D+C GD+GS L E + + C Sbjct: 180 PVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAEY 239 Query: 240 PGVYILLSKKHLNWIIMTI 258 GVY+ ++ +W+ TI Sbjct: 240 -GVYVKVTSIQ-DWVQKTI 256 >3BEU-A nrPDB Length = 224 Score = 68.2 bits (165), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 62/226 (27%), Positives = 92/226 (40%), Gaps = 22/226 (9%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 ++GG P+MV LS+ C GAL A+D VLTAAHC + + A + Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG----CGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 89 EPTKQIMLVK--KEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGT 146 + + V+ K P + T D L++L + IN+ + GT Sbjct: 57 LQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQ--PINQPTLKIATTTA---YNQGT 111 Query: 147 MCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRD 206 VAGWG S L + N+ + C + + ++ M+CAG D Sbjct: 112 FT-VAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSF---ILVANEMICAGYDTKQED 167 Query: 207 SCNGDSGSPLL-----CEGVFRGVTSFGLENKCGDPRGPGVYILLS 247 +C GDSG P+ E V G+ S+G C GVY +S Sbjct: 168 TCQGDSGGPMFRKDNADEWVQVGIVSWG--EGCARKGKYGVYTEVS 211 >4WJG-C nrPDB Length = 315 Score = 67.8 bits (164), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 63/259 (24%), Positives = 112/259 (43%), Gaps = 32/259 (12%) Query: 22 PEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAA---HCNLNKRSQV 78 P + ++I+GG+ S P+ + LI + W+LT A N ++ + Sbjct: 64 PANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATA 123 Query: 79 ILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKK 138 A ++T KQ++ ++K +P Y + D+ L++L +K +N+ V + LP K Sbjct: 124 KDIAPTLTLYVGKKQLVEIEKVVLHPNYS----QVDIGLIKLKQKVSVNERVMPICLPSK 179 Query: 139 GDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYN------------ 186 D + G + V+GWGR N ++D L+ V + + D+ C HY Sbjct: 180 -DYAEVGRVGYVSGWGRNAN-FKFTDHLKYVMLPVADQDQC--IRHYEGSTVPEKKTPKS 235 Query: 187 ---FNPVIGMNMVCAGSLRGGRDSCNGDSGSPL----LCEGVFRGVTSFGLENKCGDPRG 239 P++ + CAG + D+C GD+GS L E + + C Sbjct: 236 PVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAEY 295 Query: 240 PGVYILLSKKHLNWIIMTI 258 GVY+ ++ +W+ TI Sbjct: 296 -GVYVKVTSIQ-DWVQKTI 312 >4F4O-C nrPDB Length = 347 Score = 66.2 bits (160), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 67/262 (25%), Positives = 115/262 (43%), Gaps = 38/262 (14%) Query: 22 PEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILG 81 P D ++I+GG+ S P+ + LI + W+LT A NL LG Sbjct: 96 PVDQVQRIMGGSLDAKGSFPWQAKMISHHNLTSGATLINEQWLLTTAK-NLR------LG 148 Query: 82 AHSITREE---PTKQIMLVKK---EFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHL 135 + T+ + PT ++ + KK E + P D+ L++L +K +N+ V + L Sbjct: 149 HKNDTKAKDIAPTLRLYVGKKQEVEIEKVIFHPDNSTVDIGLIKLKQKVPVNERVMPICL 208 Query: 136 PKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVC-------------NDR 182 P K D V G + V+GWGR N ++++ L+ V + + D++ C + Sbjct: 209 PSK-DYVNVGLVGYVSGWGRNAN-LNFTEHLKYVMLPVADQEKCVQYYEGSTVPEKKTPK 266 Query: 183 NHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEG------VFRGVTSFGLENKCGD 236 + P++ + CAG + D+C GD+GS G+ SF + + Sbjct: 267 SPVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKDDDTWYAAGILSFDKSCRTAE 326 Query: 237 PRGPGVYILLSKKHLNWIIMTI 258 GVY+ ++ L+WI TI Sbjct: 327 ---YGVYVRVTSI-LDWIQTTI 344 >1AKS-B nrPDB Length = 98 Score = 63.5 bits (153), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 30/65 (46%), Positives = 41/65 (63%), Gaps = 3/65 (4%) Query: 194 NMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNW 253 NM+C G L+GG+DSC GDSG P++C G +G+ S+G C PGVY + ++NW Sbjct: 34 NMICVGFLQGGKDSCQGDSGGPVVCNGQLQGIVSWGY--GCAQKNKPGVYTKVC-NYVNW 90 Query: 254 IIMTI 258 I TI Sbjct: 91 IQQTI 95 >1M9U-A nrPDB Length = 241 Score = 63.5 bits (153), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 69/241 (28%), Positives = 104/241 (43%), Gaps = 19/241 (7%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKT-----ICAGALIAKDWVLTAAHCN---LNKRSQVIL 80 +IGG +P P+ LS R++ C +L++ L+A+HC L +VI Sbjct: 1 VIGGTNASPGEFPWQ--LSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIA 58 Query: 81 G--AHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKK 138 G S T T + Y A+ D+ +L L + + LP Sbjct: 59 GLWQQSDTSGTQTANVDSYTMHENYGA-GTASYSNDIAILHLATSISLGGNIQAAVLPAN 117 Query: 139 GDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCA 198 ++ GT C ++GWGRT + + D L++ +I +I C I N +C Sbjct: 118 NNNDYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVGGANIWDNHICV 177 Query: 199 GSLRGGRDSCNGDSGSPLLC-EGVFR--GVTSFGLENKCGD--PRGPGVYILLSKKHLNW 253 G +CNGDSG PL C +G R GVTS+ + + G P P VY +S +L W Sbjct: 178 QDPAGNTGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGACLPDYPSVYTRVS-AYLGW 236 Query: 254 I 254 I Sbjct: 237 I 237 >4BXW-A nrPDB Length = 423 Score = 62.8 bits (151), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 56/202 (27%), Positives = 92/202 (45%), Gaps = 19/202 (9%) Query: 28 KIIGGNEVTPHSRPYMVLLSLDRKTI-CAGALIAKDWVLTAAHC-NLNKRSQVILGAHSI 85 +I+ G + P+ L +++ + C G +++ +VLTAAHC N + V++G Sbjct: 169 RIVNGMDCKLGECPWQAALVDEKEGVFCGGTILSPIYVLTAAHCINETETISVVVGEIDK 228 Query: 86 TREEP----TKQIMLVKKEFPYPC----YDPATREGDLKLLQLMEKAKINKYVTILHLPK 137 +R E + + V K+F P +D A + D+ ++Q+ + ++ V LP Sbjct: 229 SRIETGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQFSENVVPACLPT 288 Query: 138 KGDDVKPGTMCQ----VAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGM 193 D M Q V+G+GR S TL+ + + +DR C + P Sbjct: 289 -ADFANQVLMKQDFGIVSGFGRIVEKGPKSKTLKVLKVPYVDRHTCMVSSETPITP---- 343 Query: 194 NMVCAGSLRGGRDSCNGDSGSP 215 NM CAG RD+C GDSG P Sbjct: 344 NMFCAGYDTLPRDACQGDSGGP 365 >2HLC-A nrPDB Length = 230 Score = 61.6 bits (148), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 59/224 (26%), Positives = 99/224 (44%), Gaps = 26/224 (11%) Query: 29 IIGGNEVTPHSRPYM----VLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHS 84 II G E PY + L R+ C G+LI W+LTAAHC + S V+ + Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHDAVSVVVYLGSA 60 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVK- 143 + E + ++ ++ + ++P T D+ L+++ + + + LP G+++ Sbjct: 61 VQYE--GEAVVNSERIISHSMFNPDTYLNDVALIKI-PHVEYTDNIQPIRLP-SGEELNN 116 Query: 144 --PGTMCQVAGWGRTHNSASWSDT--LREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAG 199 V+GWG+++ +DT L+ +ID NDR + P I + G Sbjct: 117 KFENIWATVSGWGQSN-----TDTVILQYTYNLVID----NDRCAQEYPPGIIVESTICG 167 Query: 200 SLRGGRDSCNGDSGSPLLC--EGVFRGVTSF--GLENKCGDPRG 239 G+ C GDSG P + + + GV SF G + G P G Sbjct: 168 DTSDGKSPCFGDSGGPFVLSDKNLLIGVVSFVSGAGCESGKPVG 211 >2KAI-A nrPDB Length = 80 Score = 61.2 bits (147), Expect = 5e-10, Method: Composition-based stats. Identities = 31/79 (39%), Positives = 42/79 (53%), Gaps = 1/79 (1%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 IIGG E +S P+ V + C G L+ WVLTAAHC N +V LG H++ Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQCGGVLVNPKWVLTAAHCK-NDNYEVWLGRHNLFEN 59 Query: 89 EPTKQIMLVKKEFPYPCYD 107 E T Q V +FP+P ++ Sbjct: 60 ENTAQFFGVTADFPHPGFN 78 >1GPZ-A nrPDB Length = 399 Score = 60.8 bits (146), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 67/251 (26%), Positives = 106/251 (42%), Gaps = 28/251 (11%) Query: 22 PEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQ---- 77 P + ++IIGG + + P+ V ++ + GAL+ W+LTAAH K + Sbjct: 151 PVEQRQQIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSN 208 Query: 78 ----VILGAHSITREEPTKQIMLVKKEFPYPCY---DPATREGDLKLLQLMEKAKINKYV 130 V LG H+ E +++ +P Y + EGD+ LL+L + + Sbjct: 209 ASLDVFLG-HTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNL 267 Query: 131 TILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVC-NDRNHYNFNP 189 + LP G M V+G+G + LR V + + + + C N N Sbjct: 268 LPICLPDNDTFYDLGLMGYVSGFGVMEEKIA--HDLRFVRLPVANPQACENWLRGKNRMD 325 Query: 190 VIGMNMVCAGSLRGGRDSCNGDSG------SPLLCEGVFRGVTSFGLENKCGDPRGPGVY 243 V NM CAG +D+C GDSG P V G+ S+G+ G RG G Y Sbjct: 326 VFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGI----GCSRGYGFY 381 Query: 244 ILLSKKHLNWI 254 + +++WI Sbjct: 382 TKVL-NYVDWI 391 >3H7O-A nrPDB Length = 228 Score = 60.5 bits (145), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 59/242 (24%), Positives = 105/242 (43%), Gaps = 30/242 (12%) Query: 31 GGNEVTPHSRPYMVLLSL---DRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITR 87 GG + P+ V + + C GA++++ +VLTAAHC +++ + I+ + T Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTN 61 Query: 88 --EEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLME-------KAKINKYVTILHLPKK 138 E+P K V + Y T E D+ +L+L K+K K I PK Sbjct: 62 LWEDPGKSDPYVSHVY-LSFYRQETMENDIAILELSRPLKLDGLKSKPAKLPDIEFRPKT 120 Query: 139 GDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPV-IGMNMVC 197 G DV V+G+G L+ +T++D C + + P+ + + + C Sbjct: 121 GSDV------LVSGYGDGQTMDPKDHDLKSAQLTVVDLDECRTK----YGPIFLSLQVFC 170 Query: 198 AGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMT 257 A + G +GD+G P + + GV ++ + G P V+ + +++WI Sbjct: 171 AQKV--GVSLESGDAGDPTVQQDTLVGVAAYFPKRPEG---APEVFTKVG-SYVSWIQDI 224 Query: 258 IK 259 IK Sbjct: 225 IK 226 >1MD7-A nrPDB Length = 328 Score = 60.1 bits (144), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 66/251 (26%), Positives = 105/251 (41%), Gaps = 28/251 (11%) Query: 22 PEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAH--------CNLN 73 P + ++IIGG + + P+ V ++ + GAL+ W+LTAAH N Sbjct: 83 PVEQRQRIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSN 140 Query: 74 KRSQVILGAHSITREEPTKQIMLVKKEFPYPCY---DPATREGDLKLLQLMEKAKINKYV 130 V LG H+ E +++ +P Y + EGD+ LL+L + + Sbjct: 141 ASLDVFLG-HTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNL 199 Query: 131 TILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVC-NDRNHYNFNP 189 + LP G M V+G+G + LR V + + + + C N N Sbjct: 200 LPICLPDNDTFYDLGLMGYVSGFGVMEEKIA--HDLRFVRLPVANPQACENWLRGKNRMD 257 Query: 190 VIGMNMVCAGSLRGGRDSCNGDSG------SPLLCEGVFRGVTSFGLENKCGDPRGPGVY 243 V NM CAG +D+C GD+G P V G+ S+G+ G RG G Y Sbjct: 258 VFSQNMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVSWGI----GCSRGYGFY 313 Query: 244 ILLSKKHLNWI 254 + +++WI Sbjct: 314 TKVL-NYVDWI 323 >2QY0-B nrPDB Length = 242 Score = 60.1 bits (144), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 66/244 (27%), Positives = 101/244 (41%), Gaps = 28/244 (11%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAH--------CNLNKRSQVIL 80 IIGG + + P+ V ++ + GAL+ W+LTAAH N V L Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSNASLDVFL 58 Query: 81 GAHSITREEPTKQIMLVKKEFPYPCY---DPATREGDLKLLQLMEKAKINKYVTILHLPK 137 G H+ E +++ +P Y + EGD+ LL+L + + + LP Sbjct: 59 G-HTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICLPD 117 Query: 138 KGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVC-NDRNHYNFNPVIGMNMV 196 G M V+G+G + LR V + + + + C N N V NM Sbjct: 118 NDTFYDLGLMGYVSGFGVMEEKIA--HDLRFVRLPVANPQACENWLRGKNRMDVFSQNMF 175 Query: 197 CAGSLRGGRDSCNGDSG------SPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKH 250 CAG +D+C GDSG P V G+ S+G+ G RG G Y + + Sbjct: 176 CAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGI----GCSRGYGFYTKV-LNY 230 Query: 251 LNWI 254 ++WI Sbjct: 231 VDWI 234 >1BBR-H nrPDB Length = 150 Score = 51.2 bits (121), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 42/142 (29%), Positives = 68/142 (47%), Gaps = 16/142 (11%) Query: 29 IIGGNEVTPHSRPYMVLL--SLDRKTICAGALIAKDWVLTAAHCNLNKRSQ--------- 77 I+ G + P+ V+L ++ +C +LI+ WVLTAAHC L Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 78 VILGAHSITR-EEPTKQIMLVKKEFPYPCYD-PATREGDLKLLQLMEKAKINKYVTILHL 135 V +G HS TR E ++I ++ K + +P Y+ + D+ LL+L +++ Y+ + L Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCL 120 Query: 136 PKKGDDVK---PGTMCQVAGWG 154 P K K G +V GWG Sbjct: 121 PDKQTAAKLLHAGFKGRVTGWG 142 >1RIW-B nrPDB Length = 147 Score = 50.4 bits (119), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 38/142 (26%), Positives = 72/142 (50%), Gaps = 16/142 (11%) Query: 29 IIGGNEVTPHSRPYMVLL--SLDRKTICAGALIAKDWVLTAAHC--------NLNKRSQV 78 I+ G++ P+ V+L ++ +C +LI+ WVLTAAHC N + + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 79 I-LGAHSITR-EEPTKQIMLVKKEFPYPCYD-PATREGDLKLLQLMEKAKINKYVTILHL 135 + +G HS TR E ++I +++K + +P Y+ + D+ L++L + + Y+ + L Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL 120 Query: 136 PKK---GDDVKPGTMCQVAGWG 154 P + ++ G +V GWG Sbjct: 121 PDRETAASLLQAGYKGRVTGWG 142 >1EPT-B nrPDB Length = 82 Score = 47.8 bits (112), Expect = 5e-06, Method: Composition-based stats. Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 2/82 (2%) Query: 75 RSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILH 134 R QV LG H+I E +Q + K +P ++ T + D+ L++L A +N V + Sbjct: 2 RIQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVS 61 Query: 135 LPKKGDDVKPGTMCQVAGWGRT 156 LP+ GT C ++GWG T Sbjct: 62 LPRSC--AAAGTECLISGWGNT 81 >2I6S-A nrPDB Length = 517 Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 53/239 (22%), Positives = 95/239 (39%), Gaps = 35/239 (14%) Query: 30 IGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITREE 89 + N P+ V + + C GALI+ WVLTAAHC + + + + Sbjct: 233 MSANASDQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKS 292 Query: 90 PTKQIMLVKKEFPYPCYDPATREG---------DLKLLQLMEKAKINKYVTILHLPKKGD 140 + L++K P +D ++ D+ LL+L +K K++ + + LP + Sbjct: 293 QWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTME 352 Query: 141 D----VKP-GTMCQ-----------VAGWGRTHNSASWSDTLRE-VNITIIDRKVCNDRN 183 +P G+ C+ V N + + L+ V T V ++ Sbjct: 353 ANLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKT 412 Query: 184 HY----NFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFR----GVTSFGLENKC 234 + + V+ +C+G+ + C G+SG + E FR G+ S+GL N C Sbjct: 413 MFPNLTDVREVVTDQFLCSGT-QEDESPCKGESGGAVFLERRFRFFQVGLVSWGLYNPC 470 >1DLE-A nrPDB Length = 298 Score = 40.4 bits (93), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 56/244 (22%), Positives = 103/244 (42%), Gaps = 48/244 (19%) Query: 38 HSRPYMVLLSLDRKT----ICAGALIAKDWVLTAAHC-NLNKRSQVILGAHSITREEPTK 92 H +P+ +S+ R + C GA++++ +VLTAAHC ++ + I + + + Sbjct: 25 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGGEKRDLEI 84 Query: 93 QIMLVKKEFPYPCYD---------PATREGDLKLLQLMEKAKINKYVTILHLP-----KK 138 +++L +P Y+ P + D+ L++L K K + + + LP + Sbjct: 85 EVVLF-----HPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTR 139 Query: 139 GDDVKPGTMCQVAGW----GRTHNSASWSD-----TLREVNITIIDRK-VCNDRNHY--- 185 + P T CQ + + S+ T +EV I D+K C Y Sbjct: 140 ALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYAPG 199 Query: 186 -----NFNPVIGMNMVCAGSLRGGRD--SCNGDSGSPLLCEGVFR----GVTSFGLENKC 234 + + V+ +C G + D +C GDSG PL+ R GV S+G+ + C Sbjct: 200 YDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWGVVDVC 259 Query: 235 GDPR 238 + + Sbjct: 260 KNQK 263 >2WIN-I nrPDB Length = 507 Score = 40.4 bits (93), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 59/244 (24%), Positives = 104/244 (42%), Gaps = 48/244 (19%) Query: 38 HSRPYMVLLSLDRKT----ICAGALIAKDWVLTAAHC-NLNKRSQVILGAHSITREEPTK 92 H +P+ +S+ R + C GA++++ +VLTAAHC ++ + I S+ E+ Sbjct: 232 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSI--KVSVGGEKRDL 289 Query: 93 QIMLVKKEFPYPCYD---------PATREGDLKLLQLMEKAKINKYVTILHLP-----KK 138 +I +V +P Y+ P + D+ L++L K K + + + LP + Sbjct: 290 EIEVV---LFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTR 346 Query: 139 GDDVKPGTMCQVAGW----GRTHNSASWSD-----TLREVNITIIDRK-VCNDRNHY--- 185 + P T CQ + + S+ T +EV I D+K C Y Sbjct: 347 ALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYAPG 406 Query: 186 -----NFNPVIGMNMVCAGSLRGGRD--SCNGDSGSPLLCEGVFR----GVTSFGLENKC 234 + + V+ +C G + D +C GDSG PL+ R GV S+G+ + C Sbjct: 407 YDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWGVVDVC 466 Query: 235 GDPR 238 + + Sbjct: 467 KNQK 470 >2OK5-A nrPDB Length = 752 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 59/240 (24%), Positives = 102/240 (42%), Gaps = 48/240 (20%) Query: 38 HSRPYMVLLSLDRKT----ICAGALIAKDWVLTAAHC-NLNKRSQVILGAHSITREEPTK 92 H +P+ +S+ R + C GA++++ +VLTAAHC ++ + I S+ E+ Sbjct: 476 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSI--KVSVGGEKRDL 533 Query: 93 QIMLVKKEFPYPCYD---------PATREGDLKLLQLMEKAKINKYVTILHLP-----KK 138 +I +V +P Y+ P + D+ L++L K K + + + LP + Sbjct: 534 EIEVV---LFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTR 590 Query: 139 GDDVKPGTMCQVAGW----GRTHNSASWSD-----TLREVNITIIDRK-VCNDRNHY--- 185 + P T CQ + + S+ T +EV I D+K C Y Sbjct: 591 ALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYAPG 650 Query: 186 -----NFNPVIGMNMVCAGSLRGGRD--SCNGDSGSPLLCEGVFR----GVTSFGLENKC 234 + + V+ +C G + D +C GDSG PL+ R GV S+G+ + C Sbjct: 651 YDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWGVVDVC 710 >3H5C-B nrPDB Length = 317 Score = 37.7 bits (86), Expect = 0.005, Method: Compositional matrix adjust. Identities = 39/166 (23%), Positives = 74/166 (44%), Gaps = 11/166 (6%) Query: 21 IPEDVCE-KIIGGNEVTP--HSRPYMV-LLSLDRKTICAGALIAKDWVLTAAHCNLNKRS 76 +P D C ++ + P P+ V L + + K C G +I +++VLT A C+L R+ Sbjct: 83 VPHDQCACGVLTSEKRAPDLQDLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRN 142 Query: 77 QVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLP 136 + + T ++P ++ + + YD E DL LL+L + + P Sbjct: 143 ITVKTYFNRTSQDPL--MIKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTP 200 Query: 137 KKGDD---VKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVC 179 +K + P T ++GW R N ++L +T+++ + C Sbjct: 201 EKDFAEHLLIPRTRGLLSGWAR--NGTDLGNSLTTRPVTLVEGEEC 244 >2JET-C nrPDB Length = 99 Score = 37.7 bits (86), Expect = 0.005, Method: Compositional matrix adjust. Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 12/84 (14%) Query: 164 DTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCE--GV 221 + L++ + I+ C V M CAG+ G DSC GDSG PL+C+ GV Sbjct: 7 EKLQQAALPIVSEADCKKSWGSKITDV----MTCAGA--SGVDSCMGDSGGPLVCQKDGV 60 Query: 222 FR--GVTSFGLENKCGDPRGPGVY 243 + G+ S+G C PGVY Sbjct: 61 WTLAGIVSWG-SGVCSTST-PGVY 82 >3RU4-E nrPDB Length = 96 Score = 37.7 bits (86), Expect = 0.005, Method: Compositional matrix adjust. Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 13/99 (13%) Query: 164 DTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCE--GV 221 D L++ ++ ++ C + I M+CAG+ G SC GDSG PL+C+ G Sbjct: 4 DRLQQASLPLLSNTNCKKY----WGTKIKDAMICAGA--SGVSSCMGDSGGPLVCKKNGA 57 Query: 222 FR--GVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 + G+ S+G + C PGVY ++ +NW+ T+ Sbjct: 58 WTLVGIVSWG-SSTCSTST-PGVYARVT-ALVNWVQQTL 93 >3F1S-B nrPDB Length = 283 Score = 37.7 bits (86), Expect = 0.005, Method: Compositional matrix adjust. Identities = 39/166 (23%), Positives = 74/166 (44%), Gaps = 11/166 (6%) Query: 21 IPEDVCE-KIIGGNEVTP--HSRPYMV-LLSLDRKTICAGALIAKDWVLTAAHCNLNKRS 76 +P D C ++ + P P+ V L + + K C G +I +++VLT A C+L R+ Sbjct: 42 VPHDQCACGVLTSEKRAPDLQDLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRN 101 Query: 77 QVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLP 136 + + T ++P ++ + + YD E DL LL+L + + P Sbjct: 102 ITVKTYFNRTSQDPL--MIKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTP 159 Query: 137 KKGDD---VKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVC 179 +K + P T ++GW R N ++L +T+++ + C Sbjct: 160 EKDFAEHLLIPRTRGLLSGWAR--NGTDLGNSLTTRPVTLVEGEEC 203 >2HNT-F nrPDB Length = 105 Score = 37.4 bits (85), Expect = 0.007, Method: Compositional matrix adjust. Identities = 27/74 (36%), Positives = 36/74 (48%), Gaps = 13/74 (17%) Query: 165 TLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSL--RGGR-DSCNGDSGSPLLCEGV 221 L+ VN+ I++R VC D I NM CAG G R D+C GDSG P + + Sbjct: 5 VLQVVNLPIVERPVCKDSTRIR----ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSP 60 Query: 222 FR------GVTSFG 229 F G+ S+G Sbjct: 61 FNNRWYQMGIVSWG 74 >2HNT-C nrPDB Length = 70 Score = 35.0 bits (79), Expect = 0.030, Method: Compositional matrix adjust. Identities = 22/70 (31%), Positives = 36/70 (51%), Gaps = 11/70 (15%) Query: 29 IIGGNEVTPHSRPYMVLL--SLDRKTICAGALIAKDWVLTAAHC--------NLNKRSQV 78 I+ G++ P+ V+L ++ +C +LI+ WVLTAAHC N + + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 79 I-LGAHSITR 87 + +G HS TR Sbjct: 61 VRIGKHSRTR 70 >1BBR-E nrPDB Length = 109 Score = 33.1 bits (74), Expect = 0.12, Method: Compositional matrix adjust. Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 13/74 (17%) Query: 165 TLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRG-GR--DSCNGDSGSPLLCEGV 221 L+ VN+ +++R VC I NM CAG G G+ D+C GDSG P + + Sbjct: 9 VLQVVNLPLVERPVCKASTRIR----ITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSP 64 Query: 222 FR------GVTSFG 229 + G+ S+G Sbjct: 65 YNNRWYQMGIVSWG 78 >4IM4-A nrPDB Length = 336 Score = 29.6 bits (65), Expect = 1.6, Method: Compositional matrix adjust. Identities = 15/44 (34%), Positives = 22/44 (50%) Query: 219 EGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKGAV 262 E V RG+ F +N +P Y LL++K L+W I A+ Sbjct: 288 EAVSRGIAVFWWDNGYYNPGDAETYALLNRKTLSWYYPEIVQAL 331 >4NES-A nrPDB Length = 374 Score = 28.5 bits (62), Expect = 3.4, Method: Compositional matrix adjust. Identities = 16/54 (29%), Positives = 26/54 (48%) Query: 23 EDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRS 76 E + +I +V +P +V++ D T+ AGAL+A + AH RS Sbjct: 69 EQTGKMLIEIEKVLLKEKPDVVVVQGDTNTVLAGALVASKLKIDVAHVEAGLRS 122 >4HWF-A nrPDB Length = 88 Score = 27.7 bits (60), Expect = 5.8, Method: Compositional matrix adjust. Identities = 12/31 (38%), Positives = 19/31 (61%) Query: 107 DPATREGDLKLLQLMEKAKINKYVTILHLPK 137 D +GD+KL++ M+ ++ KYV L L K Sbjct: 54 DAIIADGDVKLMRKMQVQRVQKYVEALDLLK 84 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1ORF-A nrPDB 339 9e-94 1F7Z-A nrPDB 315 1e-86 4AN7-A nrPDB 313 4e-86 5FXL-A nrPDB 312 1e-85 1UTJ-A nrPDB 308 2e-84 5C67-A nrPDB 301 2e-82 4WWY-A nrPDB 301 2e-82 1A0J-A nrPDB 298 2e-81 1SGF-G nrPDB 291 2e-79 1FXY-A nrPDB 287 3e-78 4NFE-A nrPDB 287 4e-78 1FI8-A nrPDB 285 1e-77 1EUF-A nrPDB 285 1e-77 1MZD-A nrPDB 281 2e-76 1SPJ-A nrPDB 278 1e-75 3W94-A nrPDB 277 2e-75 3QUM-P nrPDB 277 3e-75 2EEK-A nrPDB 277 3e-75 3T2N-A nrPDB 277 3e-75 5MS3-A nrPDB 276 6e-75 5TJX-A nrPDB 275 1e-74 6I44-A nrPDB 275 1e-74 1IAU-A nrPDB 275 1e-74 2TLD-E nrPDB 275 1e-74 1NPM-A nrPDB 275 1e-74 1NN6-A nrPDB 273 4e-74 3G01-A nrPDB 273 7e-74 4DGJ-A nrPDB 272 9e-74 1EKB-B nrPDB 272 1e-73 2F83-A nrPDB 272 2e-73 3BSQ-A nrPDB 271 2e-73 1FDP-A nrPDB 270 3e-73 1AO5-A nrPDB 270 4e-73 1BRU-P nrPDB 270 4e-73 5UGG-A nrPDB 270 5e-73 6QHB-A nrPDB 270 5e-73 1X7A-C nrPDB 269 7e-73 3LC3-A nrPDB 269 1e-72 5GVT-A nrPDB 269 1e-72 3DFJ-A nrPDB 269 1e-72 4DUR-A nrPDB 269 1e-72 3E0N-B nrPDB 268 1e-72 1P57-B nrPDB 267 5e-72 1SGF-A nrPDB 266 8e-72 5ZFH-A nrPDB 265 1e-71 3K65-B nrPDB 265 2e-71 1PYT-D nrPDB 264 2e-71 1TON-A nrPDB 264 3e-71 3TK9-A nrPDB 264 3e-71 4H4F-A nrPDB 264 3e-71 3NXP-A nrPDB 264 4e-71 4IGD-A nrPDB 264 4e-71 1KIG-H nrPDB 264 4e-71 2PSX-A nrPDB 263 5e-71 2OQ5-A nrPDB 262 8e-71 4NZQ-A nrPDB 262 1e-70 4GSO-A nrPDB 261 2e-70 4KKD-A nrPDB 260 4e-70 6AOD-C nrPDB 260 5e-70 5FCR-A nrPDB 260 6e-70 1C5M-D nrPDB 260 6e-70 4MPW-A nrPDB 259 9e-70 3P8G-A nrPDB 258 2e-69 2CGA-A nrPDB 258 2e-69 1MKW-K nrPDB 255 1e-68 3RP2-A nrPDB 255 1e-68 2V35-A nrPDB 255 2e-68 1GVZ-A nrPDB 254 2e-68 2F91-A nrPDB 254 3e-68 1LTO-A nrPDB 253 6e-68 1ELT-A nrPDB 253 8e-68 1FUJ-A nrPDB 252 8e-68 1BDA-A nrPDB 252 9e-68 2AIQ-A nrPDB 252 1e-67 4E7N-A nrPDB 251 2e-67 1YC0-A nrPDB 250 4e-67 2BDH-A nrPDB 250 6e-67 1KYN-A nrPDB 250 6e-67 2RDL-A nrPDB 250 6e-67 1A5I-A nrPDB 250 6e-67 1BQY-A nrPDB 248 2e-66 4Z6A-H nrPDB 248 2e-66 1Q3X-A nrPDB 248 2e-66 1OP0-A nrPDB 246 6e-66 2R0L-A nrPDB 246 7e-66 4Q7Y-A nrPDB 245 1e-65 1FON-A nrPDB 245 1e-65 4XDE-A nrPDB 245 2e-65 1FIZ-A nrPDB 245 2e-65 1ZJK-A nrPDB 245 2e-65 3S9B-A nrPDB 244 2e-65 3F6U-H nrPDB 244 3e-65 3S69-A nrPDB 243 4e-65 2ZKS-A nrPDB 242 9e-65 4IW4-E nrPDB 242 1e-64 2OCV-B nrPDB 242 1e-64 5LHN-A nrPDB 241 3e-64 1FIW-A nrPDB 241 3e-64 1VR1-H nrPDB 241 3e-64 1ELV-A nrPDB 240 3e-64 4DJZ-B nrPDB 240 4e-64 1SC8-U nrPDB 240 6e-64 1ETT-H nrPDB 239 8e-64 4FXG-H nrPDB 237 4e-63 1AZZ-A nrPDB 235 2e-62 4J1Y-A nrPDB 234 3e-62 5TO3-B nrPDB 230 6e-61 1MD7-A nrPDB 229 7e-61 1GPZ-A nrPDB 229 8e-61 5LPF-A nrPDB 229 9e-61 1AE5-A nrPDB 225 2e-59 1PPF-E nrPDB 222 1e-58 5UBM-A nrPDB 221 2e-58 2XXL-A nrPDB 221 3e-58 1EQ9-A nrPDB 219 8e-58 5XRF-A nrPDB 219 9e-58 4BXW-A nrPDB 219 9e-58 5KWM-A nrPDB 218 2e-57 2QY0-B nrPDB 217 3e-57 2XRC-A nrPDB 217 3e-57 2OLG-A nrPDB 217 4e-57 1YM0-A nrPDB 216 8e-57 4WJG-C nrPDB 214 3e-56 6BQM-A nrPDB 214 3e-56 5O32-I nrPDB 213 4e-56 4LK4-A nrPDB 213 7e-56 4F4O-C nrPDB 212 2e-55 2B9L-A nrPDB 210 5e-55 4X0L-C nrPDB 209 1e-54 3I77-A nrPDB 208 2e-54 1PQ7-A nrPDB 207 3e-54 3BEU-A nrPDB 203 4e-53 2ASU-B nrPDB 198 2e-51 2FMJ-A nrPDB 196 7e-51 2HLC-A nrPDB 196 1e-50 1SI5-H nrPDB 194 4e-50 3H7T-A nrPDB 191 3e-49 5XW8-A nrPDB 188 2e-48 1M9U-A nrPDB 183 7e-47 3H7O-A nrPDB 183 7e-47 2PKA-B nrPDB 175 1e-44 3VGC-B nrPDB 171 4e-43 2JET-B nrPDB 168 3e-42 2I6S-A nrPDB 161 4e-40 1RIW-B nrPDB 157 5e-39 2WIN-I nrPDB 156 8e-39 1DLE-A nrPDB 154 5e-38 1BBR-H nrPDB 153 8e-38 2OK5-A nrPDB 152 1e-37 1AKS-B nrPDB 134 4e-32 2KAI-A nrPDB 119 9e-28 1EPT-B nrPDB 110 5e-25 Sequences not found previously or not previously below threshold: 2HNT-F nrPDB 99 2e-21 1BBR-E nrPDB 97 6e-21 3RU4-E nrPDB 94 8e-20 3F1S-B nrPDB 93 2e-19 2JET-C nrPDB 91 3e-19 3H5C-B nrPDB 91 6e-19 2HNT-E nrPDB 81 3e-16 2HNT-C nrPDB 81 4e-16 1P3E-A nrPDB 43 1e-04 3LT3-A nrPDB 36 0.025 1DUE-A nrPDB 35 0.043 2HRV-A nrPDB 33 0.18 4GE0-A nrPDB 31 0.45 3H7V-A nrPDB 31 0.53 5UBM-B nrPDB 31 0.53 5ILB-A nrPDB 31 0.55 4FLN-A nrPDB 31 0.55 2PFE-A nrPDB 31 0.65 2EA3-A nrPDB 30 0.86 5JYK-A nrPDB 30 0.95 2OUA-A nrPDB 30 0.95 5OJX-A nrPDB 30 1.0 2SFA-A nrPDB 30 1.2 2M5T-A nrPDB 30 1.3 5ILA-A nrPDB 29 1.8 4V1Y-A nrPDB 29 2.6 4NSY-A nrPDB 28 3.4 3JUS-A nrPDB 28 3.4 4NCX-A nrPDB 28 3.5 1SMP-I nrPDB 28 3.5 3RIM-A nrPDB 28 4.3 3W95-A nrPDB 28 4.7 4FVB-A nrPDB 28 4.7 5X88-A nrPDB 28 5.4 6F74-A nrPDB 27 7.4 >1ORF-A nrPDB Length = 234 Score = 339 bits (869), Expect = 9e-94, Method: Composition-based stats. Identities = 232/234 (99%), Positives = 232/234 (99%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 60 Query: 89 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMC 148 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQL EKAKINKYVTILHLPKKGDDVKPGTMC Sbjct: 61 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDVKPGTMC 120 Query: 149 QVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSC 208 QVAGWGRTHNSASWSDTLREV ITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSC Sbjct: 121 QVAGWGRTHNSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSC 180 Query: 209 NGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKGAV 262 NGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKGAV Sbjct: 181 NGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKGAV 234 >1F7Z-A nrPDB Length = 233 Score = 315 bits (807), Expect = 1e-86, Method: Composition-based stats. Identities = 84/243 (34%), Positives = 122/243 (50%), Gaps = 12/243 (4%) Query: 19 LLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQV 78 P D + I+GG +S PY V L+ C G+LI WV++AAHC R QV Sbjct: 1 EAFPVDDDDAIVGGYTCQENSVPYQVSLNS-GYHFCGGSLINDQWVVSAAHC-YKSRIQV 58 Query: 79 ILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKK 138 LG H+I E +Q + K +P +D T D+ L++L K+N V + LP Sbjct: 59 RLGEHNINVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVALPSS 118 Query: 139 GDDVKPGTMCQVAGWGRTHNSA-SWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVC 197 GT C ++GWG T +S + D L+ ++ ++ + C + I NMVC Sbjct: 119 C--APAGTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEAS----YPGKITDNMVC 172 Query: 198 AGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMT 257 G L GG+DSC GDSG P++C G +G+ S+G C P PGVY + +++WI T Sbjct: 173 VGFLEGGKDSCQGDSGGPVVCNGELQGIVSWGY--GCALPDNPGVYTKVC-NYVDWIQDT 229 Query: 258 IKG 260 I Sbjct: 230 IAA 232 >4AN7-A nrPDB Length = 231 Score = 313 bits (803), Expect = 4e-86, Method: Composition-based stats. Identities = 83/241 (34%), Positives = 122/241 (50%), Gaps = 12/241 (4%) Query: 21 IPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVIL 80 P D +KI+GG +S PY V L+ C G+LI WV++AAHC R QV L Sbjct: 1 FPTDDDDKIVGGYTCAANSIPYQVSLNS-GSHFCGGSLINSQWVVSAAHC-YKSRIQVRL 58 Query: 81 GAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGD 140 G H+I E +Q + K +P ++ T + D+ L++L A +N V + LP+ Sbjct: 59 GEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSC- 117 Query: 141 DVKPGTMCQVAGWGRTHNSA-SWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAG 199 GT C ++GWG T +S S+ L+ + ++ C + I NM+C G Sbjct: 118 -AAAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSS----YPGQITGNMICVG 172 Query: 200 SLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 L GG+DSC GDSG P++C G +G+ S+G C PGVY + ++NWI TI Sbjct: 173 FLEGGKDSCQGDSGGPVVCNGQLQGIVSWGY--GCAQKNKPGVYTKVC-NYVNWIQQTIA 229 Query: 260 G 260 Sbjct: 230 A 230 >5FXL-A nrPDB Length = 246 Score = 312 bits (800), Expect = 1e-85, Method: Composition-based stats. Identities = 83/249 (33%), Positives = 126/249 (50%), Gaps = 12/249 (4%) Query: 12 LSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCN 71 L+++ + + P D +KI+GG ++ PY V L+ C G+LI WV++AAHC Sbjct: 7 LALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNS-GYHFCGGSLINSQWVVSAAHC- 64 Query: 72 LNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVT 131 QV LG +I E +Q + K +P Y+ T D+ L++L A +N V Sbjct: 65 YKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVA 124 Query: 132 ILHLPKKGDDVKPGTMCQVAGWGRTHNSAS-WSDTLREVNITIIDRKVCNDRNHYNFNPV 190 + LP GT C ++GWG T +S + + D L+ + I+ C + Sbjct: 125 SISLPTSCAS--AGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSA----YPGQ 178 Query: 191 IGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKH 250 I NM CAG L GG+DSC GDSG P++C G +G+ S+G + C PGVY + + Sbjct: 179 ITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWG--SGCAQKNKPGVYTKVC-NY 235 Query: 251 LNWIIMTIK 259 ++WI TI Sbjct: 236 VSWIKQTIA 244 >1UTJ-A nrPDB Length = 242 Score = 308 bits (789), Expect = 2e-84, Method: Composition-based stats. Identities = 87/246 (35%), Positives = 136/246 (55%), Gaps = 13/246 (5%) Query: 14 VVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLN 73 +++ ED +KI+GG E P+S+P+ V L+ C G+L+ ++WV++AAHC Sbjct: 8 LLIGAAFATED--DKIVGGYECKPYSQPHQVSLNS-GYHFCGGSLVNENWVVSAAHC-YK 63 Query: 74 KRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTIL 133 R +V LG H+I E ++Q + + +P Y + D+ L++L + A +N YV + Sbjct: 64 SRVEVRLGEHNIKVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPATLNTYVQPV 123 Query: 134 HLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGM 193 LP GTMC V+GWG T +S + S+ L+ +NI I+ CN+ + +I Sbjct: 124 ALPTSC--APAGTMCTVSGWGNTMSSTADSNKLQCLNIPILSYSDCNNS----YPGMITN 177 Query: 194 NMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNW 253 M CAG L GG+DSC GDSG P++C G +GV S+G C +P PGVY + +W Sbjct: 178 AMFCAGYLEGGKDSCQGDSGGPVVCNGELQGVVSWGY--GCAEPGNPGVYAKVCI-FNDW 234 Query: 254 IIMTIK 259 + T+ Sbjct: 235 LTSTMA 240 >5C67-A nrPDB Length = 224 Score = 301 bits (771), Expect = 2e-82, Method: Composition-based stats. Identities = 79/233 (33%), Positives = 121/233 (51%), Gaps = 12/233 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 I+GG +S PY V L+ C G+LI++ WV++AAHC R QV LG H+I Sbjct: 1 IVGGYTCEENSLPYQVSLNS-GSHFCGGSLISEQWVVSAAHC-YKTRIQVRLGEHNIKVL 58 Query: 89 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMC 148 E +Q + K +P Y+ T + D+ L++L A IN V+ + LP GT C Sbjct: 59 EGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAP--PAAGTEC 116 Query: 149 QVAGWGRTHN-SASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDS 207 ++GWG T + A + D L+ ++ ++ + C + I +M C G L GG+DS Sbjct: 117 LISGWGNTLSFGADYPDELKCLDAPVLTQAECKAS----YPGKITNSMFCVGFLEGGKDS 172 Query: 208 CNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 C D+G P++C G +GV S+G + C PGVY + +++WI TI Sbjct: 173 CQRDAGGPVVCNGQLQGVVSWG--HGCAWKNRPGVYTKV-YNYVDWIKDTIAA 222 >4WWY-A nrPDB Length = 224 Score = 301 bits (771), Expect = 2e-82, Method: Composition-based stats. Identities = 81/233 (34%), Positives = 120/233 (51%), Gaps = 12/233 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 I+GG +S PY V L+ C G+LI + WV++A HC R QV LG H+I Sbjct: 1 IVGGYNCEENSVPYQVSLNS-GYHFCGGSLINEQWVVSAGHC-YKSRIQVRLGEHNIEVL 58 Query: 89 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMC 148 E +Q + K +P YD T D+ L++L +A IN +V+ + LP GT C Sbjct: 59 EGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLPTAP--PATGTKC 116 Query: 149 QVAGWGRTHNSAS-WSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDS 207 ++GWG T +S + + D L+ ++ ++ + C + I NM C G L GG+DS Sbjct: 117 LISGWGNTASSGADYPDELQCLDAPVLSQAKCEAS----YPGKITSNMFCVGFLEGGKDS 172 Query: 208 CNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 C DSG P++C G +GV S+G + C PGVY + ++ WI TI Sbjct: 173 CQRDSGGPVVCNGQLQGVVSWG--DGCAQKNKPGVYTKV-YNYVKWIKNTIAA 222 >1A0J-A nrPDB Length = 223 Score = 298 bits (763), Expect = 2e-81, Method: Composition-based stats. Identities = 84/231 (36%), Positives = 123/231 (53%), Gaps = 12/231 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 I+GG E +S Y L C G+LI+ WV++AAHC R QV LG H+I Sbjct: 1 IVGGYECRKNSASYQASLQS-GYHFCGGSLISSTWVVSAAHC-YKSRIQVRLGEHNIAVN 58 Query: 89 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMC 148 E T+Q + K +P Y+ + D+ L++L + A +N YV+ + LP GT C Sbjct: 59 EGTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALPSSCAS--SGTRC 116 Query: 149 QVAGWGRTH-NSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDS 207 V+GWG +S+++ DTLR +++ I+ CN + I NM CAG + GG+DS Sbjct: 117 LVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSA----YPGQITSNMFCAGFMEGGKDS 172 Query: 208 CNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 C GDSG P++C G +GV S+G C PGVY + + +WI T+ Sbjct: 173 CQGDSGGPVVCNGQLQGVVSWGY--GCAQRNKPGVYTKVC-NYRSWISSTM 220 >1SGF-G nrPDB Length = 237 Score = 291 bits (745), Expect = 2e-79, Method: Composition-based stats. Identities = 82/243 (33%), Positives = 131/243 (53%), Gaps = 21/243 (8%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 I+GG + +S+P+ V + + +C G L+ +WVLTAAHC + +V LG +++ ++ Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQYLCGGVLLDPNWVLTAAHC-YDDNYKVWLGKNNLFKD 59 Query: 89 EPTKQIMLVKKEFPYPCYDPA-----------TREGDLKLLQLMEKAKINKYVTILHLPK 137 EP+ Q V K P+P ++ + DL LL+L + A I V + LP Sbjct: 60 EPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPITLPT 119 Query: 138 KGDDVKPGTMCQVAGWGR-THNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMV 196 ++ K G+ C +GWG T ++D L VN+ ++ + C + + M+ Sbjct: 120 --EEPKLGSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHI----EKVTDAML 173 Query: 197 CAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIM 256 CAG + GG+D+C GDSG PL+C+GV +G+TS+G CG+P PGVY L K +WI Sbjct: 174 CAGEMDGGKDTCKGDSGGPLICDGVLQGITSWGH-TPCGEPDMPGVYTKL-NKFTSWIKD 231 Query: 257 TIK 259 T+ Sbjct: 232 TMA 234 >1FXY-A nrPDB Length = 228 Score = 287 bits (735), Expect = 3e-78, Method: Composition-based stats. Identities = 70/235 (29%), Positives = 115/235 (48%), Gaps = 12/235 (5%) Query: 29 IIGGNEVTPHSRPYMVLL-SLDRKTICAGALIAKDWVLTAAHCNLN-KRSQVILGAHSIT 86 I+GG P+ LL + + + C G ++++ ++LTAAHC KR +V +G + Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTE 60 Query: 87 REEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGT 146 +EE + + V+ + + T + D+ +L+L V LP GT Sbjct: 61 QEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLPTAP--PATGT 118 Query: 147 MCQVAGWGRTHNSAS-WSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 205 C ++GWG T +S + + D L+ ++ ++ + C + I NM C G L GG+ Sbjct: 119 KCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEAS----YPGKITSNMFCVGFLEGGK 174 Query: 206 DSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 DSC GDSG P++C G +GV S+G + C PGVY + ++ WI TI Sbjct: 175 DSCQGDSGGPVVCNGQLQGVVSWG--DGCAQKNKPGVYTKV-YNYVKWIKNTIAA 226 >4NFE-A nrPDB Length = 237 Score = 287 bits (734), Expect = 4e-78, Method: Composition-based stats. Identities = 87/244 (35%), Positives = 121/244 (49%), Gaps = 21/244 (8%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 I+GG E HS+P+ V + C G L+ WVLTAAHC L K SQV LG H++ Sbjct: 1 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHC-LKKNSQVWLGRHNLFEP 59 Query: 89 EPTKQIMLVKKEFPYPCYD-----------PATREGDLKLLQLMEKAKINKYVTILHLPK 137 E T Q + V FP+P Y+ DL LL+L E AKI V +L LP Sbjct: 60 EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 119 Query: 138 KGDDVKPGTMCQVAGWGRTHNSASW-SDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMV 196 + + GT C +GWG +L+ V++ ++ +C ++ + M+ Sbjct: 120 QEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARA----YSEKVTEFML 173 Query: 197 CAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIM 256 CAG GG+D+C GDSG PL+C GV +G+TS+G C P P VY + + WI Sbjct: 174 CAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWG-PEPCALPEKPAVYTKV-VHYRKWIKD 231 Query: 257 TIKG 260 TI Sbjct: 232 TIAA 235 >1FI8-A nrPDB Length = 228 Score = 285 bits (731), Expect = 1e-77, Method: Composition-based stats. Identities = 96/235 (40%), Positives = 131/235 (55%), Gaps = 13/235 (5%) Query: 29 IIGGNEVTPHSRPYMVLLS----LDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHS 84 IIGG+E PHSRPYM L C G LI +D+VLTAAHC + QV LGAH+ Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC-SGSKIQVTLGAHN 59 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKP 144 I +E +QI+ V K P+P Y+ T D+ LL+L KAK + V L+LP++ VKP Sbjct: 60 IKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 119 Query: 145 GTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 204 G +C VAGWG+ +SDTL+EV +T+ + + C Y N N +CAG + Sbjct: 120 GDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCES---YLKNYFDKANEICAGDPKIK 176 Query: 205 RDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 R S GDSG PL+C+ V G+ S+G + P + +S L+WI T+K Sbjct: 177 RASFRGDSGGPLVCKKVAAGIVSYGQNDG----STPRAFTKVST-FLSWIKKTMK 226 >1EUF-A nrPDB Length = 227 Score = 285 bits (730), Expect = 1e-77, Method: Composition-based stats. Identities = 94/234 (40%), Positives = 135/234 (57%), Gaps = 13/234 (5%) Query: 29 IIGGNEVTPHSRPYMVLL---SLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSI 85 IIGG+E PHSRPYM L + + IC G L+ +D+VLTAAHC L V LGAH+I Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHC-LGSSINVTLGAHNI 59 Query: 86 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 E T+Q++ V++ P+P Y+ T D+ LL+L KA I V+ ++LP+ +VKPG Sbjct: 60 MERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAEVKPG 119 Query: 146 TMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 205 MC VAGWGR + +D L+EV++ + + C R F I +CAG + Sbjct: 120 MMCSVAGWGRLGVNMPSTDKLQEVDLEVQSEEKCIAR----FKNYIPFTQICAGDPSKRK 175 Query: 206 DSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 +S +GDSG PL+C GV +G+ S+G + P VY +S L+WI T++ Sbjct: 176 NSFSGDSGGPLVCNGVAQGIVSYGRNDG----TTPDVYTRIS-SFLSWIHSTMR 224 >1MZD-A nrPDB Length = 240 Score = 281 bits (719), Expect = 2e-76, Method: Composition-based stats. Identities = 103/236 (43%), Positives = 148/236 (62%), Gaps = 8/236 (3%) Query: 28 KIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNL----NKRSQVILGAH 83 +IIGG EV+PHSRP+M + +C G LI WVLTAAHC + V+LGAH Sbjct: 2 EIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAH 61 Query: 84 SITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVK 143 S+++ E +KQ + +KK P+ + D+ L++L AK+NK+V +LH+ K ++ Sbjct: 62 SLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSK-TSLR 120 Query: 144 PGTMCQVAGWGRTHNSA-SWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 202 GT C+V GWG T + SDTLREV +T++ RK+CN +++YN +P I +MVCAG + Sbjct: 121 SGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAK 180 Query: 203 GGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 G +DSC GD+G PL+C+GVF + S G E CG PG+Y LL+KK+ WI + Sbjct: 181 GQKDSCKGDAGGPLICKGVFHAIVSGGHE--CGVATKPGIYTLLTKKYQTWIKSNL 234 >1SPJ-A nrPDB Length = 238 Score = 278 bits (712), Expect = 1e-75, Method: Composition-based stats. Identities = 84/244 (34%), Positives = 125/244 (51%), Gaps = 22/244 (9%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 I+GG E HS+P+ L C G L+ + WVLTAAHC + Q+ LG H++ + Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCI-SDNYQLWLGRHNLFDD 59 Query: 89 EPTKQIMLVKKEFPYPCYD-----------PATREGDLKLLQLMEKA-KINKYVTILHLP 136 E T Q + V + FP+P ++ DL LL+L E A I V ++ LP Sbjct: 60 ENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVELP 119 Query: 137 KKGDDVKPGTMCQVAGWGRTH-NSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNM 195 + +V G+ C +GWG + S+ D L+ V++ I+ C + + M Sbjct: 120 TEEPEV--GSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQ----KVTDFM 173 Query: 196 VCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWII 255 +C G L GG+D+C GDSG PL+C+GV +GVTS+G CG P P V + + ++ WI Sbjct: 174 LCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYV-PCGTPNKPSVAVRV-LSYVKWIE 231 Query: 256 MTIK 259 TI Sbjct: 232 DTIA 235 >3W94-A nrPDB Length = 235 Score = 277 bits (710), Expect = 2e-75, Method: Composition-based stats. Identities = 76/239 (31%), Positives = 113/239 (47%), Gaps = 16/239 (6%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQV-----ILGAH 83 ++GG + P+MV L + C +LI +DW+LTAAHC K + + +LG H Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRGRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVLGLH 60 Query: 84 SITREEPTK-QIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDV 142 + + + QI V + Y+ T+E D+ ++ L + ++V + L + Sbjct: 61 AQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLASEDQHF 120 Query: 143 KPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 202 G C +AGWGR S D L+E + ++D+ C +M+CAG Sbjct: 121 PAGRRCFIAGWGRDAEGGSLPDILQEAEVPLVDQDECQRLLP---EYTFTSSMLCAGYPE 177 Query: 203 GGRDSCNGDSGSPLLC----EGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMT 257 GG DSC GDSG PL+C GVTSFG+ CG P PG Y +S +WI T Sbjct: 178 GGVDSCQGDSGGPLMCLEDARWTLIGVTSFGV--GCGRPERPGAYARVSA-FTSWIAET 233 >3QUM-P nrPDB Length = 237 Score = 277 bits (710), Expect = 3e-75, Method: Composition-based stats. Identities = 84/242 (34%), Positives = 124/242 (51%), Gaps = 21/242 (8%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 I+GG E HS+P+ VL++ + +C G L+ WVLTAAHC NK ++LG HS+ Sbjct: 1 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSV-ILLGRHSLFHP 59 Query: 89 EPTKQIMLVKKEFPYPCYDPATREG-----------DLKLLQLMEKAKINKYVTILHLPK 137 E T Q+ V FP+P YD + + DL LL+L E A++ V ++ LP Sbjct: 60 EDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPT 119 Query: 138 KGDDVKPGTMCQVAGWGRTHNSASW-SDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMV 196 + + GT C +GWG L+ V++ +I VC + + M+ Sbjct: 120 QEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH----PQKVTKFML 173 Query: 197 CAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIM 256 CAG GG+ +C+GDSG PL+C GV +G+TS+G C P P +Y + + WI Sbjct: 174 CAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWG-SEPCALPERPSLYTKV-VHYRKWIKD 231 Query: 257 TI 258 TI Sbjct: 232 TI 233 >2EEK-A nrPDB Length = 220 Score = 277 bits (710), Expect = 3e-75, Method: Composition-based stats. Identities = 82/231 (35%), Positives = 124/231 (53%), Gaps = 11/231 (4%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 I+GG E T HS+ + V L+ C G+L++KDWV++AAHC +V LG H I Sbjct: 1 IVGGYECTKHSQAHQVSLNS-GYHFCGGSLVSKDWVVSAAHC-YKSVLRVRLGEHHIRVN 58 Query: 89 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMC 148 E T+Q + +P Y D+ L++L + A +N+YV + LP + TMC Sbjct: 59 EGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPT--ECAADATMC 116 Query: 149 QVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSC 208 V+GWG T +S + D L+ +++ I+ C + + +I +M CAG L GG+DSC Sbjct: 117 TVSGWGNTMSSVADGDKLQCLSLPILSHADCANS----YPGMITQSMFCAGYLEGGKDSC 172 Query: 209 NGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 GDSG P++C GV +GV S+G C + PGVY + W+ T+ Sbjct: 173 QGDSGGPVVCNGVLQGVVSWGY--GCAERDHPGVYAKVCVL-SGWVRDTMA 220 >3T2N-A nrPDB Length = 372 Score = 277 bits (709), Expect = 3e-75, Method: Composition-based stats. Identities = 77/270 (28%), Positives = 116/270 (42%), Gaps = 26/270 (9%) Query: 9 ASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAA 68 L+ + + ++I+GG + + P+ V L D +C G+L++ DWVLTAA Sbjct: 98 GRFLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAA 157 Query: 69 HCNLNKR-----SQVILGAHSITREEPTKQIMLVKKEFPYPCY------DPATREGDLKL 117 HC + +V GA + + P + V+ + Y + D+ L Sbjct: 158 HCFPERNRVLSRWRVFAGA--VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIAL 215 Query: 118 LQLMEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRK 177 + L + +Y+ + LP G + G +C V GWG T + L+E + II Sbjct: 216 VHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISND 275 Query: 178 VCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCE--------GVFRGVTSFG 229 VCN + Y I M CAG GG D+C GDSG P +CE G+ S+G Sbjct: 276 VCNGADFYG--NQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWG 333 Query: 230 LENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 C + PGVY +S WI IK Sbjct: 334 --TGCALAQKPGVYTKVSD-FREWIFQAIK 360 >5MS3-A nrPDB Length = 228 Score = 276 bits (707), Expect = 6e-75, Method: Composition-based stats. Identities = 86/234 (36%), Positives = 128/234 (54%), Gaps = 14/234 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 ++GG+E PHS+P+ L ++ +C G L+ +WVLTAAHC + V LG HS+ + Sbjct: 1 VLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCK-KPKYTVRLGDHSLQNK 59 Query: 89 EPTKQIMLVKKEFPYPCYDP---ATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 + +Q + V + P+PCY+ DL LLQL ++A + V + L +PG Sbjct: 60 DGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCT--QPG 117 Query: 146 TMCQVAGWGR-THNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 204 C V+GWG T ++ DTL + I +K C D + I MVCAGS + G Sbjct: 118 QKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDA----YPGQITDGMVCAGSSK-G 172 Query: 205 RDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 D+C GDSG PL+C+G +G+TS+G + CG PGVY + ++L+WI I Sbjct: 173 ADTCQGDSGGPLVCDGALQGITSWG-SDPCGRSDKPGVYTNIC-RYLDWIKKII 224 >5TJX-A nrPDB Length = 263 Score = 275 bits (705), Expect = 1e-74, Method: Composition-based stats. Identities = 71/250 (28%), Positives = 118/250 (47%), Gaps = 17/250 (6%) Query: 23 EDVCEKIIGGNEVTPHSRPYMVLLSLD---RKTICAGALIAKDWVLTAAHCN----LNKR 75 +I+GG E + P+ V L + ++ +C G+LI WVLTAAHC L Sbjct: 10 TKTSTRIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDV 69 Query: 76 SQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHL 135 ++ G ++ +K+ + Y + D+ L++L + ++ + L Sbjct: 70 WRIYSGILELSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLEYTEFQKPISL 129 Query: 136 PKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNM 195 P KGD T C V GWG + + L++VNI ++ + C R + I M Sbjct: 130 PSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQ---DYKITQRM 186 Query: 196 VCAGSLRGGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHL 251 VCAG GG+D+C GDSG PL+C+ G+TS+G C PGVY +++ ++ Sbjct: 187 VCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG--EGCARREQPGVYTKVAE-YM 243 Query: 252 NWIIMTIKGA 261 +WI+ + + Sbjct: 244 DWILEKTQSS 253 >6I44-A nrPDB Length = 627 Score = 275 bits (704), Expect = 1e-74, Method: Composition-based stats. Identities = 69/250 (27%), Positives = 119/250 (47%), Gaps = 17/250 (6%) Query: 23 EDVCEKIIGGNEVTPHSRPYMVLLSLD---RKTICAGALIAKDWVLTAAHCN----LNKR 75 +I+GG + + P+ V L + ++ +C G+LI WVLTAAHC L Sbjct: 374 TKTSTRIVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDV 433 Query: 76 SQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHL 135 ++ G ++ +K+ + Y + D+ L++L + ++ + L Sbjct: 434 WRIYSGILQLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLQYTEFQKPICL 493 Query: 136 PKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNM 195 P KGD T C V GWG + + + L++VNI ++ + C R + I M Sbjct: 494 PSKGDTSTIYTNCWVTGWGFSAEAGEIQNILQKVNIPLVTNEECQKRYQ---DYKITQRM 550 Query: 196 VCAGSLRGGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHL 251 VCAG GG+D+C GD+G PL+C+ G+TS+G C PGVY +++ ++ Sbjct: 551 VCAGYKEGGKDACKGDAGGPLVCKHNGMWRLVGITSWG--EGCARREQPGVYTKVAE-YM 607 Query: 252 NWIIMTIKGA 261 +WI+ + + Sbjct: 608 DWILEKTQSS 617 >1IAU-A nrPDB Length = 227 Score = 275 bits (704), Expect = 1e-74, Method: Composition-based stats. Identities = 95/234 (40%), Positives = 128/234 (54%), Gaps = 12/234 (5%) Query: 29 IIGGNEVTPHSRPYMVLL-SLDRKTI--CAGALIAKDWVLTAAHCNLNKRSQVILGAHSI 85 IIGG+E PHSRPYM L D+K++ C G LI D+VLTAAHC V LGAH+I Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-WGSSINVTLGAHNI 59 Query: 86 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 +EPT+Q + VK+ P+P Y+P D+ LLQL KAK + V L LP VKPG Sbjct: 60 KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 119 Query: 146 TMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 205 C VAGWG+T S TL+EV +T+ + + C + ++ I +C G + Sbjct: 120 QTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTI---ELCVGDPEIKK 176 Query: 206 DSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 S GDSG PL+C V +G+ S+G N P +S ++WI T+K Sbjct: 177 TSFKGDSGGPLVCNKVAQGIVSYGRNNG----MPPRACTKVS-SFVHWIKKTMK 225 >2TLD-E nrPDB Length = 220 Score = 275 bits (704), Expect = 1e-74, Method: Composition-based stats. Identities = 77/232 (33%), Positives = 113/232 (48%), Gaps = 15/232 (6%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 I+GG ++ PY V L+ C G+LI WV++AAHC QV LG +I Sbjct: 1 IVGGYTCGANTVPYQVSLNS-GYHFCGGSLINSQWVVSAAHC-YKSGIQVRLGEDNINVV 58 Query: 89 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMC 148 E +Q + K +P Y+ T D+ L++L A +N V + LP GT C Sbjct: 59 EGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCAS--AGTQC 116 Query: 149 QVAGWGRTHNSAS-WSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDS 207 ++GWG T +S + + D L+ + I+ C + I NM CAG G DS Sbjct: 117 LISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSA----YPGQITSNMFCAGLE--GGDS 170 Query: 208 CNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 C GDSG P++C G +G+ S+G + C PGVY + +++WI TI Sbjct: 171 CQGDSGGPVVCSGKLQGIVSWG--SGCA-KNKPGVYTKVC-NYVSWIKQTIA 218 >1NPM-A nrPDB Length = 225 Score = 275 bits (704), Expect = 1e-74, Method: Composition-based stats. Identities = 80/234 (34%), Positives = 119/234 (50%), Gaps = 14/234 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 I+ G E PHS+P+ L + IC G L+ WVLTAAHC ++ V LG HS+ Sbjct: 1 ILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAAHCK-KQKYSVRLGDHSLQSR 59 Query: 89 EPTKQIMLVKKEFPYPCY---DPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 + +Q + V + +PCY +P D+ L++L A + V + L K G Sbjct: 60 DQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQL--ANLCPKVG 117 Query: 146 TMCQVAGWGR-THNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 204 C ++GWG T ++ +TL + I + C + I MVCAGS G Sbjct: 118 QKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERA----YPGKITEGMVCAGS-SNG 172 Query: 205 RDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 D+C GDSG PL+C+G+ +G+TS+G + CG P PGVY + ++ WI T+ Sbjct: 173 ADTCQGDSGGPLVCDGMLQGITSWG-SDPCGKPEKPGVYTKIC-RYTTWIKKTM 224 >1NN6-A nrPDB Length = 228 Score = 273 bits (699), Expect = 4e-74, Method: Composition-based stats. Identities = 95/238 (39%), Positives = 133/238 (55%), Gaps = 15/238 (6%) Query: 27 EKIIGGNEVTPHSRPYMVLL----SLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGA 82 +IIGG E PHSRPYM L S C G LI +++VLTAAHC + V LGA Sbjct: 1 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC-AGRSITVTLGA 59 Query: 83 HSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDV 142 H+IT EE T Q + V K+F +P Y+ +T D+ LL+L EKA + V L P + + V Sbjct: 60 HNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFV 119 Query: 143 KPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 202 PG MC+VAGWGRT SDTL+EV + ++D + C+ ++ N +C G+ R Sbjct: 120 PPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNL-----QLCVGNPR 174 Query: 203 GGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 + + GDSG PLLC GV +G+ S+G D + P V+ +S + WI ++ Sbjct: 175 KTKSAFKGDSGGPLLCAGVAQGIVSYGRS----DAKPPAVFTRIS-HYRPWINQILQA 227 >3G01-A nrPDB Length = 227 Score = 273 bits (698), Expect = 7e-74, Method: Composition-based stats. Identities = 90/235 (38%), Positives = 129/235 (54%), Gaps = 13/235 (5%) Query: 29 IIGGNEVTPHSRPYMV---LLSLDRK-TICAGALIAKDWVLTAAHCNLNKRSQVILGAHS 84 IIGGNE++PHSRPYM L + K C G L+ +VLTAAHC + V LGAH+ Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHCK-GRSMTVTLGAHN 59 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKP 144 I +E T+QI+ V K P+P Y+P R D+ LL+L+ AK + V L+LP++ VKP Sbjct: 60 IKAKEETQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNAHVKP 119 Query: 145 GTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 204 G C VAGWG+ + TL EV +T+ +VC + ++N N +C G + Sbjct: 120 GDECYVAGWGKVTPDGEFPKTLHEVKLTVQKDQVCESQFQSSYNRA---NEICVGDSKIK 176 Query: 205 RDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 S GDSG PL+C+ G+ S+G + P V+ + ++WI T+K Sbjct: 177 GASFRGDSGGPLVCKRAAAGIVSYGQTDGSA----PQVFTRV-LSFVSWIKKTMK 226 >4DGJ-A nrPDB Length = 235 Score = 272 bits (697), Expect = 9e-74, Method: Composition-based stats. Identities = 74/238 (31%), Positives = 117/238 (49%), Gaps = 16/238 (6%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKR-----SQVILGAH 83 I+GG++ + P++V L D + +C +L++ DW+++AAHC + ILG H Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLH 60 Query: 84 SITR-EEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDV 142 + P L+ + P Y+ ++ D+ ++ L K Y+ + LP++ Sbjct: 61 MKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPEENQVF 120 Query: 143 KPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 202 PG C +AGWG + +D L+E ++ ++ + C + I NM+CAG Sbjct: 121 PPGRNCSIAGWGTVVYQGTTADILQEADVPLLSNERCQQQMP---EYNITENMICAGYEE 177 Query: 203 GGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIM 256 GG DSC GDSG PL+C+ GVTSFG E C P PGVY +S + WI Sbjct: 178 GGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYE--CALPNRPGVYARVS-RFTEWIQS 232 >1EKB-B nrPDB Length = 235 Score = 272 bits (695), Expect = 1e-73, Method: Composition-based stats. Identities = 73/238 (30%), Positives = 120/238 (50%), Gaps = 16/238 (6%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKR-----SQVILGAH 83 I+GG++ + P++V L D + +C +L+++DW+++AAHC + + +LG H Sbjct: 1 IVGGSDSREGAWPWVVALYFDDQQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVLGLH 60 Query: 84 SITR-EEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDV 142 + P + L+ + P Y+ + D+ ++ L K Y+ + LP++ Sbjct: 61 MASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLPEENQVF 120 Query: 143 KPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 202 PG +C +AGWG S +D L+E ++ ++ + C + I NMVCAG Sbjct: 121 PPGRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQQMP---EYNITENMVCAGYEA 177 Query: 203 GGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIM 256 GG DSC GDSG PL+C+ + GVTSFG + C P PGVY + + WI Sbjct: 178 GGVDSCQGDSGGPLMCQENNRWLLAGVTSFGYQ--CALPNRPGVYARV-PRFTEWIQS 232 >2F83-A nrPDB Length = 625 Score = 272 bits (695), Expect = 2e-73, Method: Composition-based stats. Identities = 70/249 (28%), Positives = 110/249 (44%), Gaps = 17/249 (6%) Query: 23 EDVCEKIIGGNEVTPHSRPYMVLL---SLDRKTICAGALIAKDWVLTAAHCNLN----KR 75 + +I+GG P+ V L S ++ +C G++I W+LTAAHC K Sbjct: 382 TKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKI 441 Query: 76 SQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHL 135 +V G + + + V++ + Y A D+ LL+L + L Sbjct: 442 LRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICL 501 Query: 136 PKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNM 195 P KGD T C V GWG +TL++ I ++ + C R + I M Sbjct: 502 PSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGH---KITHKM 558 Query: 196 VCAGSLRGGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHL 251 +CAG GG+D+C GDSG PL C+ G+TS+G C PGVY + +++ Sbjct: 559 ICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWG--EGCAQRERPGVYTNV-VEYV 615 Query: 252 NWIIMTIKG 260 +WI+ + Sbjct: 616 DWILEKTQA 624 >3BSQ-A nrPDB Length = 227 Score = 271 bits (694), Expect = 2e-73, Method: Composition-based stats. Identities = 78/232 (33%), Positives = 119/232 (51%), Gaps = 12/232 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 II G S P+ V L + C G L+ + WVLTAAHC +N+ V LG+ ++ Sbjct: 1 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNE-YTVHLGSDTLGDR 59 Query: 89 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMC 148 Q + K F +P Y T DL L++L +A+++ V + LP + + PGT C Sbjct: 60 R--AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPGTTC 115 Query: 149 QVAGWG-RTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDS 207 V+GWG T ++ L V++ +I + C + ++ +M+CAG +++ Sbjct: 116 TVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKV----YKDLLENSMLCAGIPDSKKNA 171 Query: 208 CNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 CNGDSG PL+C G +G+ S+G CG P PGVY + K WI T+K Sbjct: 172 CNGDSGGPLVCRGTLQGLVSWG-TFPCGQPNDPGVYTQVC-KFTKWINDTMK 221 >1FDP-A nrPDB Length = 235 Score = 270 bits (692), Expect = 3e-73, Method: Composition-based stats. Identities = 95/238 (39%), Positives = 140/238 (58%), Gaps = 9/238 (3%) Query: 25 VCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCN---LNKRSQVILG 81 +I+GG E H+RPYM + L+ +C G L+A+ WVL+AAHC + + QV+LG Sbjct: 4 PRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLG 63 Query: 82 AHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDD 141 AHS+++ EP+K++ V + P+P P T + DL LLQL EKA + V L + D Sbjct: 64 AHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRD 123 Query: 142 VKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSL 201 V PGT+C VAGWG +++ D+L+ V + ++DR CN R H++ I ++CA S Sbjct: 124 VAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDG--AITERLMCAESN 181 Query: 202 RGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 R RDSC GDSG PL+C GV GV + G CG+ + PG+Y ++ + WI + Sbjct: 182 R--RDSCKGDSGGPLVCGGVLEGVVTSG-SRVCGNRKKPGIYTRVA-SYAAWIDSVLA 235 >1AO5-A nrPDB Length = 237 Score = 270 bits (691), Expect = 4e-73, Method: Composition-based stats. Identities = 85/242 (35%), Positives = 131/242 (54%), Gaps = 21/242 (8%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 ++GG +S+P+ V + ++ IC G L+ ++WVLTAAHC +++ +V LG + + +E Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQ-YEVWLGKNKLFQE 59 Query: 89 EPTKQIMLVKKEFPYPCYDP-----------ATREGDLKLLQLMEKAKINKYVTILHLPK 137 EP+ Q LV K FP+P ++ A DL LL+L + A I V + LP Sbjct: 60 EPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPIALPT 119 Query: 138 KGDDVKPGTMCQVAGWGR-THNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMV 196 K + KPG+ C +GWG T D L+ V IT++ + C + + M+ Sbjct: 120 K--EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKV----YLQKVTDVML 173 Query: 197 CAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIM 256 CAG + GG+D+C DSG PL+C+G+ +G TS+G CG P P +Y L K +WI Sbjct: 174 CAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPV-PCGKPGVPAIYTNL-IKFNSWIKD 231 Query: 257 TI 258 T+ Sbjct: 232 TM 233 >1BRU-P nrPDB Length = 241 Score = 270 bits (691), Expect = 4e-73, Method: Composition-based stats. Identities = 73/243 (30%), Positives = 116/243 (47%), Gaps = 16/243 (6%) Query: 29 IIGGNEVTPHSRPYMVLLSLDR----KTICAGALIAKDWVLTAAHCNLNKR-SQVILGAH 83 ++GG + P+S P+ V L D + C G L+ + WVLTAAHC + R +V+LG H Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRH 60 Query: 84 SITREEPTKQIMLVKKEFPYPCYDPA--TREGDLKLLQLMEKAKINKYVTILHLPKKGDD 141 S++ EP + V K + ++ + D+ LL+L + + + LP G Sbjct: 61 SLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAGTI 120 Query: 142 VKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSL 201 + +C V GWGR + + D L++ + ++D C+ + + NM+CAG Sbjct: 121 LPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWG--STVKTNMICAGG- 177 Query: 202 RGGRDSCNGDSGSPLLC-----EGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIM 256 G SCNGDSG PL C + G+ SFG C P V+ +S +++WI Sbjct: 178 DGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVS-NYIDWINS 236 Query: 257 TIK 259 I Sbjct: 237 VIA 239 >5UGG-A nrPDB Length = 251 Score = 270 bits (690), Expect = 5e-73, Method: Composition-based stats. Identities = 88/255 (34%), Positives = 120/255 (47%), Gaps = 21/255 (8%) Query: 14 VVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLD-RKTICAGALIAKDWVLTAAHCN- 71 + P+ +++GG PHS P+ V L C G LI+ +WVLTAAHC Sbjct: 7 DCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLE 66 Query: 72 ---LNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINK 128 +VILGAH EP Q + V + F P D+ LL+L A I Sbjct: 67 KSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPT------RKDIALLKLSSPAVITD 120 Query: 129 YVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFN 188 V LP V T C + GWG T + L+E + +I+ KVCN N Sbjct: 121 KVIPACLPSPNYVVADRTECFITGWGETQ-GTFGAGLLKEAQLPVIENKVCNRYEFLNGR 179 Query: 189 PVIGMNMVCAGSLRGGRDSCNGDSGSPLLC----EGVFRGVTSFGLENKCGDPRGPGVYI 244 + +CAG L GG DSC GDSG PL+C + + +GVTS+GL C P PGVY+ Sbjct: 180 --VQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGL--GCARPNKPGVYV 235 Query: 245 LLSKKHLNWIIMTIK 259 +S + + WI ++ Sbjct: 236 RVS-RFVTWIEGVMR 249 >6QHB-A nrPDB Length = 223 Score = 270 bits (690), Expect = 5e-73, Method: Composition-based stats. Identities = 80/231 (34%), Positives = 121/231 (52%), Gaps = 10/231 (4%) Query: 30 IGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITREE 89 + G S PY L +C G LI WVLTAAHC QV LG H++ ++E Sbjct: 2 VHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCK-KPNLQVFLGKHNLGQQE 60 Query: 90 PTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMCQ 149 +++ V + +P YD A+ + D+ LL+L AK+++ + LP + D T C Sbjct: 61 SSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQP--LPLERDCSAQTTSCH 118 Query: 150 VAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCN 209 + GWG+T + + DT++ I ++ R+ C + + I NM+CAG + G+DSC Sbjct: 119 ILGWGKTADGD-FPDTIQCAYIHLVSREECE----HAYPGQITQNMLCAGDEKYGKDSCQ 173 Query: 210 GDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 GDSG PL+C RG+ S+G CG PGVY + ++ NWI TI+ Sbjct: 174 GDSGGPLVCGDHLRGLVSWG-NIPCGSKEKPGVYTNVC-RYTNWIQKTIQA 222 >1X7A-C nrPDB Length = 235 Score = 269 bits (689), Expect = 7e-73, Method: Composition-based stats. Identities = 77/241 (31%), Positives = 117/241 (48%), Gaps = 18/241 (7%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNL-NKRSQVILGAHSITR 87 I+GG P P+ VLL+ C G++I + WV+TAAHC + V+ G ++ Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVAGEYNTEE 60 Query: 88 EEPTKQIMLVKKEFPYPCYDPAT--REGDLKLLQLMEKAKINKYVTILHLPKKGDD---V 142 EPT+Q V + P+ Y+ D+ LL+L E +N YVT + + K + Sbjct: 61 TEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEYTNIFL 120 Query: 143 KPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 202 K G+ V+GWGR N + L+ + + ++DR C + I NM CAG Sbjct: 121 KFGS-GYVSGWGRVFNRGRSATILQYLKVPLVDRATCLRSTKF----TIYSNMFCAGFHE 175 Query: 203 GGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 GG+DSC GDSG P + E G+ S+G +C G+Y +S +++NWI Sbjct: 176 GGKDSCQGDSGGPHVTEVEGTSFLTGIISWG--EECAVKGKYGIYTKVS-RYVNWIKEKT 232 Query: 259 K 259 K Sbjct: 233 K 233 >3LC3-A nrPDB Length = 235 Score = 269 bits (687), Expect = 1e-72, Method: Composition-based stats. Identities = 75/241 (31%), Positives = 119/241 (49%), Gaps = 18/241 (7%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCN-LNKRSQVILGAHSITR 87 ++GG + P P+ V+L+ C G+++ + W++TAAHC + V+ G H+I Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEE 60 Query: 88 EEPTKQIMLVKKEFPYPCYDPAT--REGDLKLLQLMEKAKINKYVTILHLPKKGDD---V 142 E T+Q V + P+ Y+ A D+ LL+L E +N YVT + + K + Sbjct: 61 TEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFL 120 Query: 143 KPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 202 K G+ V+GWGR + + L+ + + ++DR C + I NM CAG Sbjct: 121 KFGS-GYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKF----TIYNNMFCAGFHE 175 Query: 203 GGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 GGRDSC GDSG P + E G+ S+G +C G+Y +S +++NWI Sbjct: 176 GGRDSCQGDSGGPHVTEVEGTSFLTGIISWG--EECAMKGKYGIYTKVS-RYVNWIKEKT 232 Query: 259 K 259 K Sbjct: 233 K 233 >5GVT-A nrPDB Length = 250 Score = 269 bits (687), Expect = 1e-72, Method: Composition-based stats. Identities = 67/244 (27%), Positives = 112/244 (45%), Gaps = 17/244 (6%) Query: 29 IIGGNEVTPHSRPYMVLLSLD---RKTICAGALIAKDWVLTAAHCN----LNKRSQVILG 81 I+GG + P+ V L + + +C G++I + WVLTAAHC ++ G Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 82 AHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDD 141 S++ +K+ + Y + D+ L++L ++ + LP K D Sbjct: 61 ILSLSEITKETPSSRIKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSKADT 120 Query: 142 VKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSL 201 T C V GWG T + L++ I ++ + C + + VI M+CAG Sbjct: 121 NTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYR---DYVINKQMICAGYK 177 Query: 202 RGGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMT 257 GG D+C GDSG PL+C+ G+TS+G C PGVY +S+ +++WI+ Sbjct: 178 EGGTDACKGDSGGPLVCKHSGRWQLVGITSWG--EGCARKDQPGVYTKVSE-YMDWILEK 234 Query: 258 IKGA 261 + + Sbjct: 235 TQSS 238 >3DFJ-A nrPDB Length = 263 Score = 269 bits (687), Expect = 1e-72, Method: Composition-based stats. Identities = 75/242 (30%), Positives = 118/242 (48%), Gaps = 17/242 (7%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCN----LNKRSQVILGAHS 84 I GG+ P+ V ++ + +C G+L+++ WVL+AAHC + +V LGAH Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKP 144 + ++ +K P+P Y +GD+ LLQL ++Y+ + LP Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAANASFPN 120 Query: 145 GTMCQVAGWGRTHNSASW--SDTLREVNITIIDRKVCNDRNHYNFNP----VIGMNMVCA 198 G C V GWG S S L+++ + +I R+ CN + + P + +MVCA Sbjct: 121 GLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFVQEDMVCA 180 Query: 199 GSLRGGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 G + GG+D+C GDSG PL C G+ S+G + CG PGVY L+ + +WI Sbjct: 181 GYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWG--DACGARNRPGVYT-LASSYASWI 237 Query: 255 IM 256 Sbjct: 238 QS 239 >4DUR-A nrPDB Length = 791 Score = 269 bits (687), Expect = 1e-72, Method: Composition-based stats. Identities = 88/255 (34%), Positives = 120/255 (47%), Gaps = 21/255 (8%) Query: 14 VVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLD-RKTICAGALIAKDWVLTAAHCN- 71 + P+ +++GG PHS P+ V L C G LI+ +WVLTAAHC Sbjct: 547 DCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLE 606 Query: 72 ---LNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINK 128 +VILGAH EP Q + V + F P D+ LL+L A I Sbjct: 607 KSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPT------RKDIALLKLSSPAVITD 660 Query: 129 YVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFN 188 V LP V T C + GWG T + L+E + +I+ KVCN N Sbjct: 661 KVIPACLPSPNYVVADRTECFITGWGETQ-GTFGAGLLKEAQLPVIENKVCNRYEFLNGR 719 Query: 189 PVIGMNMVCAGSLRGGRDSCNGDSGSPLLC----EGVFRGVTSFGLENKCGDPRGPGVYI 244 + +CAG L GG DSC GDSG PL+C + + +GVTS+GL C P PGVY+ Sbjct: 720 --VQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGL--GCARPNKPGVYV 775 Query: 245 LLSKKHLNWIIMTIK 259 +S + + WI ++ Sbjct: 776 RVS-RFVTWIEGVMR 789 >3E0N-B nrPDB Length = 271 Score = 268 bits (686), Expect = 1e-72, Method: Composition-based stats. Identities = 75/242 (30%), Positives = 118/242 (48%), Gaps = 17/242 (7%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCN----LNKRSQVILGAHS 84 I GG+ P+ V ++ + +C G+L+++ WVL+AAHC + +V LGAH Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKP 144 + ++ +K P+P Y +GD+ LLQL ++Y+ + LP Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQASFPN 120 Query: 145 GTMCQVAGWGRTHNSASW--SDTLREVNITIIDRKVCNDRNHYNFNP----VIGMNMVCA 198 G C V GWG S S L+++ + +I R+ CN + + P + +MVCA Sbjct: 121 GLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQEDMVCA 180 Query: 199 GSLRGGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 G + GG+D+C GDSG PL C G+ S+G + CG PGVY L+ + +WI Sbjct: 181 GYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWG--DACGARNRPGVYT-LASSYASWI 237 Query: 255 IM 256 Sbjct: 238 QS 239 >1P57-B nrPDB Length = 255 Score = 267 bits (682), Expect = 5e-72, Method: Composition-based stats. Identities = 76/250 (30%), Positives = 110/250 (44%), Gaps = 26/250 (10%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKR-----SQVILGAH 83 I+GG + + P+ V L D +C G+L++ DWVLTAAHC + +V GA Sbjct: 1 IVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGA- 59 Query: 84 SITREEPTKQIMLVKKEFPYPCY------DPATREGDLKLLQLMEKAKINKYVTILHLPK 137 + + P + V+ + Y + D+ L+ L + +Y+ + LP Sbjct: 60 -VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPA 118 Query: 138 KGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVC 197 G + G +C V GWG T + L+E + II VCN + Y I M C Sbjct: 119 AGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYG--NQIKPKMFC 176 Query: 198 AGSLRGGRDSCNGDSGSPLLCE--------GVFRGVTSFGLENKCGDPRGPGVYILLSKK 249 AG GG D+C GDSG P +CE G+ S+G C + PGVY +S Sbjct: 177 AGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWG--TGCALAQKPGVYTKVSD- 233 Query: 250 HLNWIIMTIK 259 WI IK Sbjct: 234 FREWIFQAIK 243 >1SGF-A nrPDB Length = 240 Score = 266 bits (680), Expect = 8e-72, Method: Composition-based stats. Identities = 79/238 (33%), Positives = 123/238 (51%), Gaps = 22/238 (9%) Query: 34 EVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITREEPTKQ 93 + +S+P+ V + K C G L+ ++WVLTAAHC N + QV LG ++ +EP+ Q Sbjct: 10 DCE-NSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHC-YNDKYQVWLGKNNFLEDEPSDQ 67 Query: 94 IMLVKKEFPYPCYDP-----------ATREGDLKLLQLMEKAKINKYVTILHLPKKGDDV 142 LV K P+P ++ DL LL+L + A I V + LP ++ Sbjct: 68 HRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPT--EEP 125 Query: 143 KPGTMCQVAGWGRTHN-SASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSL 201 K G+ C +GWG T + D L+ VN+ ++ + C+ + + M+CAG + Sbjct: 126 KLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEM----KVTDAMLCAGEM 181 Query: 202 RGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 GG +C DSG PL+C+G+ +G+TS+G CG+P P VY L K +WI T+ Sbjct: 182 DGGSYTCEHDSGGPLICDGILQGITSWG-PEPCGEPTEPSVYTKL-IKFSSWIRETMA 237 >5ZFH-A nrPDB Length = 224 Score = 265 bits (678), Expect = 1e-71, Method: Composition-based stats. Identities = 78/232 (33%), Positives = 118/232 (50%), Gaps = 12/232 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 II G + S P+ V L + C G L+ K WVLTAAHC + + QV LG S Sbjct: 1 IIDGYKCKEGSHPWQVALLKGNQLHCGGVLVDKYWVLTAAHCKMGQ-YQVQLG--SDKIG 57 Query: 89 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMC 148 + + Q + K F +P Y T D+ L++L E K++ V + LP+ + PGT C Sbjct: 58 DQSAQKIKATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLPEHCE--PPGTSC 115 Query: 149 QVAGWG-RTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDS 207 V+GWG T ++ L ++ +I + C + ++G M+CAG ++ Sbjct: 116 TVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKV----YKDLLGKTMLCAGIPDSKTNT 171 Query: 208 CNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 CNGDSG PL+C +G+ S+G CG P PGVY + K+ W++ T+K Sbjct: 172 CNGDSGGPLVCNDTLQGLVSWGTY-PCGQPNDPGVYTQVC-KYKRWVMETMK 221 >3K65-B nrPDB Length = 308 Score = 265 bits (677), Expect = 2e-71, Method: Composition-based stats. Identities = 73/283 (25%), Positives = 122/283 (43%), Gaps = 38/283 (13%) Query: 7 FLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLD--RKTICAGALIAKDWV 64 F SL L+ + +I+ G++ P+ V+L ++ +C +LI+ WV Sbjct: 28 FEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWV 87 Query: 65 LTAAHCNLNKRSQ---------VILGAHSITREEPT-KQIMLVKKEFPYPCYD-PATREG 113 LTAAHC L V +G HS TR E ++I +++K + +P Y+ + Sbjct: 88 LTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDR 147 Query: 114 DLKLLQLMEKAKINKYVTILHLPKK---GDDVKPGTMCQVAGWGRTHNSAS------WSD 164 D+ L++L + + Y+ + LP + ++ G +V GWG + + Sbjct: 148 DIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPS 207 Query: 165 TLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGS-LRGGR--DSCNGDSGSPLLCE-- 219 L+ VN+ I++R VC D I NM CAG G+ D+C GD+G P + + Sbjct: 208 VLQVVNLPIVERPVCKDSTRIR----ITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSP 263 Query: 220 ----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 G+ S+G C G Y + + WI I Sbjct: 264 FNNRWYQMGIVSWG--EGCDRDGKYGFYTHVFRL-KKWIQKVI 303 >1PYT-D nrPDB Length = 251 Score = 264 bits (676), Expect = 2e-71, Method: Composition-based stats. Identities = 69/253 (27%), Positives = 121/253 (47%), Gaps = 14/253 (5%) Query: 17 SLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDR----KTICAGALIAKDWVLTAAHCNL 72 + ++ +++GG + PHS P+ + L R + C G LI + VLTAAHC Sbjct: 2 GAPIFQPNLSARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCIS 61 Query: 73 NK-RSQVILGAHSITREEPTKQI-MLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYV 130 N +V LG +++ E+ + + V F + ++ D+ L++L E ++ + Sbjct: 62 NTLTYRVALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELGDTI 121 Query: 131 TILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPV 190 + LP +G + C V GWGR + + + L++ ++D C+ R+ + Sbjct: 122 QVACLPSEGSLLPQDYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQRDWWGT--T 179 Query: 191 IGMNMVCAGSLRGGRDSCNGDSGSPLLC----EGVFRGVTSFGLENKCGDPRGPGVYILL 246 + MVCAG G +CNGDSG PL C + RG+ SFG C + P V+ + Sbjct: 180 VKETMVCAGG-DGVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPTVFTRV 238 Query: 247 SKKHLNWIIMTIK 259 S +++WI ++ Sbjct: 239 SA-YIDWINQKLQ 250 >1TON-A nrPDB Length = 235 Score = 264 bits (676), Expect = 3e-71, Method: Composition-based stats. Identities = 86/243 (35%), Positives = 130/243 (53%), Gaps = 23/243 (9%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 I+GG + +S+P+ V + + +C G LI WV+TAAHC + QV+LG +++ ++ Sbjct: 1 IVGGYKCEKNSQPWQVAVI--NEYLCGGVLIDPSWVITAAHC-YSNNYQVLLGRNNLFKD 57 Query: 89 EPTKQIMLVKKEFPYPCYDPA-----------TREGDLKLLQLMEKAKINKYVTILHLPK 137 EP Q LV++ F +P Y P DL LL L E A I V ++ LP Sbjct: 58 EPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVIDLPT 117 Query: 138 KGDDVKPGTMCQVAGWGRTHNSASW-SDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMV 196 K + K G+ C +GWG T+ S S L+ VNI ++ + C + + + M+ Sbjct: 118 K--EPKVGSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIE----TYKDNVTDVML 171 Query: 197 CAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIM 256 CAG + GG+D+C GDSG PL+C+GV +G+TS G C P+ P +Y L K +WI Sbjct: 172 CAGEMEGGKDTCAGDSGGPLICDGVLQGITS-GGATPCAKPKTPAIYAKL-IKFTSWIKK 229 Query: 257 TIK 259 +K Sbjct: 230 VMK 232 >3TK9-A nrPDB Length = 226 Score = 264 bits (675), Expect = 3e-71, Method: Composition-based stats. Identities = 93/234 (39%), Positives = 127/234 (54%), Gaps = 13/234 (5%) Query: 29 IIGGNEVTPHSRPYMVL---LSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSI 85 IIGG+E PHSRPYM L + C G L+ KD+VLTAAHC V LGAH+I Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHC-QGSSINVTLGAHNI 59 Query: 86 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 +E T+Q + VK+ P+P Y+P ++ LLQL KAK V L LP VKPG Sbjct: 60 KEQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQVKPG 119 Query: 146 TMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 205 +C VAGWG + ++ + TL+EV +T+ C H N++ +C G + + Sbjct: 120 QLCSVAGWGYV-SMSTLATTLQEVLLTVQKDCQCERLFHGNYSRA---TEICVGDPKKTQ 175 Query: 206 DSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 GDSG PL+C+ V +G+ S+G + PGVYI +S L WI T+K Sbjct: 176 TGFKGDSGGPLVCKDVAQGILSYGNKKG----TPPGVYIKVS-HFLPWIKRTMK 224 >4H4F-A nrPDB Length = 249 Score = 264 bits (675), Expect = 3e-71, Method: Composition-based stats. Identities = 70/242 (28%), Positives = 118/242 (48%), Gaps = 15/242 (6%) Query: 29 IIGGNEVTPHSRPYMVLLSLDR----KTICAGALIAKDWVLTAAHCNLNKR-SQVILGAH 83 ++GG + PHS P+ + L + + C G LIA ++VLTAAHC N R +V +G + Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 60 Query: 84 SITRE-EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDV 142 ++ E E + V + ++ D+ L++L E +++ + + LP+K + Sbjct: 61 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 120 Query: 143 KPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 202 C V GWGR + +D L++ ++D C+ + + F + MVCAG Sbjct: 121 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFR--VKKTMVCAGG-D 177 Query: 203 GGRDSCNGDSGSPLLCE-----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMT 257 G +CNGDSG PL C+ G+ SFG C + P VY +S +++WI Sbjct: 178 GVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSA-YIDWINEK 236 Query: 258 IK 259 ++ Sbjct: 237 MQ 238 >3NXP-A nrPDB Length = 424 Score = 264 bits (674), Expect = 4e-71, Method: Composition-based stats. Identities = 74/283 (26%), Positives = 122/283 (43%), Gaps = 38/283 (13%) Query: 7 FLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLD--RKTICAGALIAKDWV 64 F SL L+ + +I+ G++ P+ V+L ++ +C +LI+ WV Sbjct: 144 FEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWV 203 Query: 65 LTAAHCNLNKRSQ---------VILGAHSITREEPT-KQIMLVKKEFPYPCYD-PATREG 113 LTAAHC L V +G HS TR E ++I +++K + +P Y+ + Sbjct: 204 LTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDR 263 Query: 114 DLKLLQLMEKAKINKYVTILHLPKK---GDDVKPGTMCQVAGWGRTHNSAS------WSD 164 D+ L++L + + Y+ + LP + ++ G +V GWG + + Sbjct: 264 DIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPS 323 Query: 165 TLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGS-LRGGR--DSCNGDSGSPLLCE-- 219 L+ VN+ I++R VC D I NM CAG G+ D+C GDSG P + + Sbjct: 324 VLQVVNLPIVERPVCKDSTRIR----ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSP 379 Query: 220 ----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 G+ S+G C G Y + + WI I Sbjct: 380 FNNRWYQMGIVSWG--EGCDRDGKYGFYTHVFRL-KKWIQKVI 419 >4IGD-A nrPDB Length = 406 Score = 264 bits (674), Expect = 4e-71, Method: Composition-based stats. Identities = 77/279 (27%), Positives = 127/279 (45%), Gaps = 34/279 (12%) Query: 6 RFLASSLSVVVSLLLIPE---DVCEKIIGGNEVTPHSRPYMVLLS-LDRKTICAGALIAK 61 + L SL + + +P+ + +I G + P++ +LS L+ + C G+L+ Sbjct: 130 KVLGRSLPTCLPVCGLPKFSRKLMAQIFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGS 189 Query: 62 DWVLTAAHCNL-----------------NKRSQVILGAHSITREEPTKQIMLVKKEFPYP 104 W++TAAHC ++ILG H R + +Q + VK +P Sbjct: 190 SWIVTAAHCLHQSLDPEDPTLRDSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHP 249 Query: 105 CYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSD 164 YDP T E D+ L++L+E +N +V + LP+ + G M V+GWG+ + + Sbjct: 250 QYDPNTFENDVALVELLESPVLNAFVMPICLPEGPQ--QEGAMVIVSGWGKQFLQ-RFPE 306 Query: 165 TLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLC------ 218 TL E+ I I+D C + +M+CAG GG+D+C GDSG P++ Sbjct: 307 TLMEIEIPIVDHSTCQKAYA-PLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERG 365 Query: 219 EGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMT 257 + G S+G + CG GVY + +WI Sbjct: 366 QWYLVGTVSWG--DDCGKKDRYGVYSYIHHN-KDWIQRV 401 >1KIG-H nrPDB Length = 241 Score = 264 bits (674), Expect = 4e-71, Method: Composition-based stats. Identities = 67/241 (27%), Positives = 106/241 (43%), Gaps = 16/241 (6%) Query: 29 IIGGNEVTPHSRPYMVLL-SLDRKTICAGALIAKDWVLTAAHCNLN-KRSQVILGAHSIT 86 I+GG + P+ LL + + + C G ++ + +VLTAAHC KR V +G + Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAKRFTVRVGDRNTE 60 Query: 87 REEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKG---DDVK 143 +EE + V+ + + T + D+ +L+L + + V LP+K + Sbjct: 61 QEEGNEMAHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAEATLM 120 Query: 144 PGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRG 203 V+G+GRTH S TL+ + + +DR C + + I NM CAG Sbjct: 121 TQKTGIVSGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSF----TITPNMFCAGYDTQ 176 Query: 204 GRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 D+C GDSG P + G+ S+G C GVY +S L WI +K Sbjct: 177 PEDACQGDSGGPHVTRFKDTYFVTGIVSWG--EGCARKGKFGVYTKVS-NFLKWIDKIMK 233 Query: 260 G 260 Sbjct: 234 A 234 >2PSX-A nrPDB Length = 227 Score = 263 bits (673), Expect = 5e-71, Method: Composition-based stats. Identities = 79/235 (33%), Positives = 118/235 (50%), Gaps = 13/235 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLD-RKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSIT- 86 II G++ H++P+ L L + C L+ W+LTAAHC K +V LG +S++ Sbjct: 1 IINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC-RKKVFRVRLGHYSLSP 59 Query: 87 REEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGT 146 E +Q+ K P+P Y DL L++L + + K V +++ GT Sbjct: 60 VYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS--AGT 117 Query: 147 MCQVAGWGRT-HNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 205 C V+GWG T + L+ +NI+++ +K C D + I M CAG + GR Sbjct: 118 KCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDA----YPRQIDDTMFCAGD-KAGR 172 Query: 206 DSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 DSC GDSG P++C G +G+ S+G + C P PGVY L K WI TI+ Sbjct: 173 DSCQGDSGGPVVCNGSLQGLVSWG-DYPCARPNRPGVYTNLC-KFTKWIQETIQA 225 >2OQ5-A nrPDB Length = 232 Score = 262 bits (671), Expect = 8e-71, Method: Composition-based stats. Identities = 68/233 (29%), Positives = 105/233 (45%), Gaps = 10/233 (4%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 I+GG EV P+ L D C LI W+++AAHC ++ A Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGVTI 60 Query: 89 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMC 148 +P+K +++ + Y + + D+ L +L V + LP + +PG + Sbjct: 61 KPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVM 120 Query: 149 QVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSC 208 V G+G N + LR+ +T+ID CN+ Y N I M+CAGSL G D+C Sbjct: 121 FVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAY--NDAITPRMLCAGSLEGKTDAC 178 Query: 209 NGDSGSPLLCE-----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIM 256 GDSG PL+ G+ S+G ++C P PGVY ++ +WI Sbjct: 179 QGDSGGPLVSSDARDIWYLAGIVSWG--DECAKPNKPGVYTRVTAL-RDWITS 228 >4NZQ-A nrPDB Length = 557 Score = 262 bits (669), Expect = 1e-70, Method: Composition-based stats. Identities = 74/283 (26%), Positives = 122/283 (43%), Gaps = 38/283 (13%) Query: 7 FLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLD--RKTICAGALIAKDWV 64 F SL L+ + +I+ G++ P+ V+L ++ +C +LI+ WV Sbjct: 277 FEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWV 336 Query: 65 LTAAHCNLNKRSQ---------VILGAHSITREEPT-KQIMLVKKEFPYPCYD-PATREG 113 LTAAHC L V +G HS TR E ++I +++K + +P Y+ + Sbjct: 337 LTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDR 396 Query: 114 DLKLLQLMEKAKINKYVTILHLPKK---GDDVKPGTMCQVAGWGRTHNSAS------WSD 164 D+ L++L + + Y+ + LP + ++ G +V GWG + + Sbjct: 397 DIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPS 456 Query: 165 TLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGS-LRGGR--DSCNGDSGSPLLCE-- 219 L+ VN+ I++R VC D I NM CAG G+ D+C GDSG P + + Sbjct: 457 VLQVVNLPIVERPVCKDSTRIR----ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSP 512 Query: 220 ----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 G+ S+G C G Y + + WI I Sbjct: 513 FNNRWYQMGIVSWG--EGCDRDGKYGFYTHVFRL-KKWIQKVI 552 >4GSO-A nrPDB Length = 232 Score = 261 bits (668), Expect = 2e-70, Method: Composition-based stats. Identities = 74/234 (31%), Positives = 122/234 (52%), Gaps = 12/234 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 ++GG+E + P++ L C LI ++WV+TAAHC+ + Q+ LG HS Sbjct: 1 VLGGDECDINEHPFLAFLYSHG-YFCGLTLINQEWVVTAAHCD-STNFQMQLGVHSKKVL 58 Query: 89 EPTKQIMLVKKEFPYPCYD-PATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTM 147 +Q K++F P + + D+ L++L + +K++ L LP V G++ Sbjct: 59 NEDEQTRNPKEKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPSNPPSV--GSV 116 Query: 148 CQVAGWGR-THNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRD 206 C++ GWG T + ++ D NI ++D +VC +N + +CAG L GG+D Sbjct: 117 CRIMGWGSITIPNETYPDVPYCANINLVDYEVCQ----GAYNGLPAKTTLCAGVLEGGKD 172 Query: 207 SCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 +C GDSG PL+C G F+G+ S+G + CG PG+Y + + +WI I G Sbjct: 173 TCVGDSGGPLICNGQFQGIVSYGA-HSCGQGPKPGIYTNVFD-YTDWIQRNIAG 224 >4KKD-A nrPDB Length = 433 Score = 260 bits (665), Expect = 4e-70, Method: Composition-based stats. Identities = 72/295 (24%), Positives = 127/295 (43%), Gaps = 44/295 (14%) Query: 6 RFLASSLSVVVSLLLIP----EDVCEKIIGGNEVTPHSRPYMVLLSLDR-------KTIC 54 + L SL + P + ++IIGG P P+ L+ ++ K Sbjct: 128 KVLGRSLPTCLPECGQPSRSLPSLVQRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFG 187 Query: 55 AGALIAKDWVLTAAHCNLNKR------------SQVILGAHSITREEPTKQIMLVKKEFP 102 +GAL++ W+LTAAH ++R V LG H + R++ + Sbjct: 188 SGALLSASWILTAAHVLRSQRRDTTVIPVSKEHVTVYLGLHDV-RDKSGAVNSSAARVVL 246 Query: 103 YPCYDPATREGDLKLLQLMEKAKINKYVTILHLPK-KGDDVKPGTMCQVAGWGRTHNS-- 159 +P ++ D+ L+QL E + +V + LP+ + + P + VAGWG ++ + Sbjct: 247 HPDFNIQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVT 306 Query: 160 ---------ASWSDTLREVNITIIDRKVCNDRNH-YNFNPVIGMNMVCAGSLRGGRDSCN 209 + SD L+ V + ++ C + N + NM CAG GG+D+C Sbjct: 307 VDEIISSGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCL 366 Query: 210 GDSGSPLL------CEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 GDSG + V +G+ S+G +CG + GVY +S +++W+ + Sbjct: 367 GDSGEAFVIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVS-NYVDWVWEQM 420 >6AOD-C nrPDB Length = 245 Score = 260 bits (665), Expect = 5e-70, Method: Composition-based stats. Identities = 69/243 (28%), Positives = 108/243 (44%), Gaps = 17/243 (6%) Query: 29 IIGGNEVTPHSRPYMVLL---SLDRKTICAGALIAKDWVLTAAHCNLN----KRSQVILG 81 I+GG P+ V L S ++ +C G++I W+LTAAHC K +V G Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 82 AHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDD 141 + + V++ + Y A D+ LL+L + + LP KGD Sbjct: 61 ILQQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKGDR 120 Query: 142 VKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSL 201 T C V GWG +TL++ I ++ + C R + I M+CAG Sbjct: 121 NVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGH---KITHKMICAGYR 177 Query: 202 RGGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMT 257 GG+D+C GD+G PL C+ G+TS+G C PGVY + ++++WI+ Sbjct: 178 EGGKDACKGDAGGPLSCKHNEVWHLVGITSWG--EGCAQRERPGVYTNV-VEYVDWILEK 234 Query: 258 IKG 260 + Sbjct: 235 TQA 237 >5FCR-A nrPDB Length = 234 Score = 260 bits (664), Expect = 6e-70, Method: Composition-based stats. Identities = 90/236 (38%), Positives = 137/236 (58%), Gaps = 10/236 (4%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHC----NLNKRSQVILGAHS 84 I+GG E H+RPYM + ++ +C G L+ + WVL+AAHC + QV+LGAHS Sbjct: 1 ILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHS 60 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKP 144 ++ EP K+ V+ P+P P + E DL L +L + A + +V L L + +V+P Sbjct: 61 LSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDKEVEP 120 Query: 145 GTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 204 GT+C VAGWG ++ D L ++ ++I++R CN R +++ V+ +NM+CA S R Sbjct: 121 GTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDG--VVTINMMCAESNR-- 176 Query: 205 RDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 RD+C GDSGSPL+C GV ++G CG+ + PGVY +S + WI G Sbjct: 177 RDTCRGDSGSPLVCGDAVEGVVTWG-SRVCGNGKKPGVYTRVS-SYRMWIENITNG 230 >1C5M-D nrPDB Length = 255 Score = 260 bits (664), Expect = 6e-70, Method: Composition-based stats. Identities = 63/240 (26%), Positives = 108/240 (45%), Gaps = 16/240 (6%) Query: 29 IIGGNEVTPHSRPYMVLL-SLDRKTICAGALIAKDWVLTAAHCNLN-KRSQVILGAHSIT 86 I+GG E P+ LL + + + C G ++++ ++LTAAHC KR +V +G + Sbjct: 1 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTE 60 Query: 87 REEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKG---DDVK 143 +EE + + V+ + + T + D+ +L+L V LP++ + Sbjct: 61 QEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLM 120 Query: 144 PGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRG 203 V+G+GRTH S L+ + + +DR C + + +I NM CAG Sbjct: 121 TQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSF----IITQNMFCAGYDTK 176 Query: 204 GRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 D+C GDSG P + G+ S+G C G+Y ++ L WI ++K Sbjct: 177 QEDACQGDSGGPHVTRFKDTYFVTGIVSWG--EGCARKGKYGIYTKVTA-FLKWIDRSMK 233 >4MPW-A nrPDB Length = 245 Score = 259 bits (662), Expect = 9e-70, Method: Composition-based stats. Identities = 75/245 (30%), Positives = 117/245 (47%), Gaps = 27/245 (11%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRK---TICAGALIAKDWVLTAAHCNLNKR-----SQVIL 80 I+GG E P+ V L + C G+LI WVLTAAHC +V L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 60 Query: 81 GAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGD 140 + ++ Q++ V + +P + A D+ LL+L E K++ +V + LP + Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASE 117 Query: 141 DVKPGTMCQVAGWGRTHNSASWSD--TLREVNITIIDRKVCNDRNHYNFN-----PVIGM 193 PG C V GWG N L++V + I++ +C+ + H ++ Sbjct: 118 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 177 Query: 194 NMVCAGSLRGGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKK 249 +M+CAG+ R RDSC GDSG PL+C+ + GV S+G C P PG+Y ++ Sbjct: 178 DMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWG--EGCAQPNRPGIYTRVT-Y 232 Query: 250 HLNWI 254 +L+WI Sbjct: 233 YLDWI 237 >3P8G-A nrPDB Length = 241 Score = 258 bits (660), Expect = 2e-69, Method: Composition-based stats. Identities = 71/245 (28%), Positives = 111/245 (45%), Gaps = 23/245 (9%) Query: 29 IIGGNEVTPHSRPYMVLLS-LDRKTICAGALIAKDWVLTAAHCNLNKR---------SQV 78 ++GG + P+ V L L + IC +LI+ +W+++AAHC ++ R Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTA 60 Query: 79 ILGAHSITREE-PTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPK 137 LG H ++ P Q +K+ +P ++ T + D+ LL+L + A+ + V + LP Sbjct: 61 FLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICLPD 120 Query: 138 KGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVC 197 G V GWG T + + L++ I +I + C + I M+C Sbjct: 121 ASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVIQQTTCENL----LPQQITPRMMC 176 Query: 198 AGSLRGGRDSCNGDSGSPL----LCEGVFR-GVTSFGLENKCGDPRGPGVYILLSKKHLN 252 G L GG DSC GDSG PL +F+ GV S+G + C PGVY L + Sbjct: 177 VGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWG--DGCAQRNKPGVYTRL-PLFRD 233 Query: 253 WIIMT 257 WI Sbjct: 234 WIKEN 238 >2CGA-A nrPDB Length = 245 Score = 258 bits (660), Expect = 2e-69, Method: Composition-based stats. Identities = 74/253 (29%), Positives = 113/253 (44%), Gaps = 20/253 (7%) Query: 19 LLIPEDVC-----EKIIGGNEVTPHSRPYMVLLSLDRK-TICAGALIAKDWVLTAAHCNL 72 +P +I+ G E P S P+ V L C G+LI ++WV+TAAHC + Sbjct: 1 CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGV 60 Query: 73 NKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTI 132 V+ G Q + + K F Y+ T D+ LL+L A ++ V+ Sbjct: 61 TTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSA 120 Query: 133 LHLPKKGDDVKPGTMCQVAGWGRTH-NSASWSDTLREVNITIIDRKVCNDRNHYNFNPVI 191 + LP DD GT C GWG T +A+ D L++ ++ ++ C + I Sbjct: 121 VCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKK----YWGTKI 176 Query: 192 GMNMVCAGSLRGGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLS 247 M+CAG+ G SC GDSG PL+C+ G+ S+G C PGVY ++ Sbjct: 177 KDAMICAGAS--GVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSST-CSTS-TPGVYARVT 232 Query: 248 KKHLNWIIMTIKG 260 +NW+ T+ Sbjct: 233 AL-VNWVQQTLAA 244 >1MKW-K nrPDB Length = 308 Score = 255 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 74/283 (26%), Positives = 116/283 (40%), Gaps = 38/283 (13%) Query: 7 FLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLD--RKTICAGALIAKDWV 64 F + L + +I+ G + P+ V+L ++ +C +LI+ WV Sbjct: 28 FEKKQVQDQTEKELFESYIEGRIVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWV 87 Query: 65 LTAAHCNLNKRSQ---------VILGAHSITREEPT-KQIMLVKKEFPYPCYD-PATREG 113 LTAAHC L V +G HS TR E ++I ++ K + +P Y+ + Sbjct: 88 LTAAHCLLYPPWDKNFTVDDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDR 147 Query: 114 DLKLLQLMEKAKINKYVTILHLPKKGDDVK---PGTMCQVAGWGR------THNSASWSD 164 D+ LL+L +++ Y+ + LP K K G +V GWG T + Sbjct: 148 DIALLKLKRPIELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPS 207 Query: 165 TLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG---RDSCNGDSGSPLLCE-- 219 L+ VN+ +++R VC I NM CAG G D+C GDSG P + + Sbjct: 208 VLQVVNLPLVERPVCKASTRIR----ITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSP 263 Query: 220 ----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 G+ S+G C G Y + + WI I Sbjct: 264 YNNRWYQMGIVSWG--EGCDRDGKYGFYTHVFRL-KKWIQKVI 303 >3RP2-A nrPDB Length = 224 Score = 255 bits (652), Expect = 1e-68, Method: Composition-based stats. Identities = 91/234 (38%), Positives = 127/234 (54%), Gaps = 15/234 (6%) Query: 29 IIGGNEVTPHSRPYMVLLSL----DRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHS 84 IIGG E PHSRPYM L + + IC G LI++ +VLTAAHC + VILGAH Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCK-GREITVILGAHD 59 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKP 144 + + E T+Q + V+K+ + Y+ D+ LL+L +K ++ V ++ LP D + P Sbjct: 60 VRKRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDFIHP 119 Query: 145 GTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 204 G MC AGWG+T S TLREV + I+D K C D +Y + VC GS Sbjct: 120 GAMCWAAGWGKTGVRDPTSYTLREVELRIMDEKACVDYRYYEYK-----FQVCVGSPTTL 174 Query: 205 RDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 R + GDSG PLLC GV G+ S+G D + P ++ +S ++ WI I Sbjct: 175 RAAFMGDSGGPLLCAGVAHGIVSYGHP----DAKPPAIFTRVST-YVPWINAVI 223 >2V35-A nrPDB Length = 240 Score = 255 bits (651), Expect = 2e-68, Method: Composition-based stats. Identities = 72/242 (29%), Positives = 121/242 (50%), Gaps = 15/242 (6%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRK----TICAGALIAKDWVLTAAHCNLNK-RSQVILGAH 83 ++GG E +S P + L C G LI ++WV+TAAHC + +V++G H Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEH 60 Query: 84 SITREEPTKQIMLVKKEFPYPCYDPATR--EGDLKLLQLMEKAKINKYVTILHLPKKGDD 141 ++ + + T+Q + V+K +P ++ D+ LL+L + +N YV + LP+ G Sbjct: 61 NLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRAGTI 120 Query: 142 VKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSL 201 + + C + GWG T + + TL++ + +D +C+ +++ + +MVCAG Sbjct: 121 LANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWG--STVKNSMVCAGG- 177 Query: 202 RGGRDSCNGDSGSPLLC----EGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMT 257 G R C GDSG PL C + GVTSF C R P V+ +S +++WI Sbjct: 178 DGVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSA-YISWINNV 236 Query: 258 IK 259 I Sbjct: 237 IA 238 >1GVZ-A nrPDB Length = 237 Score = 254 bits (650), Expect = 2e-68, Method: Composition-based stats. Identities = 78/243 (32%), Positives = 113/243 (46%), Gaps = 21/243 (8%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 IIGG E HS+P+ V + C G L+ WVLTAAHC + Q+ LG H+++++ Sbjct: 1 IIGGWECEKHSKPWQVAVYHQGHFQCGGVLVHPQWVLTAAHCMSDD-YQIWLGRHNLSKD 59 Query: 89 EPTKQIMLVKKEFPYPCYD-----------PATREGDLKLLQLMEKAKINKYVTILHLPK 137 E T Q V F P +D DL LL+L + A+I V IL LP Sbjct: 60 EDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVKILDLPT 119 Query: 138 KGDDVKPGTMCQVAGWGRTHN-SASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMV 196 + K G+ C +GWG + S TL+ V + + + C + + ++ Sbjct: 120 --QEPKLGSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARA----YPEKMTEFVL 173 Query: 197 CAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIM 256 CA C GDSG L+C+GVF+G+TS+G C D V+ + H WI Sbjct: 174 CATHRDDSGSICLGDSGGALICDGVFQGITSWGYSE-CADFNDNFVFTKV-MPHKKWIKE 231 Query: 257 TIK 259 TI+ Sbjct: 232 TIE 234 >2F91-A nrPDB Length = 237 Score = 254 bits (649), Expect = 3e-68, Method: Composition-based stats. Identities = 66/243 (27%), Positives = 105/243 (43%), Gaps = 22/243 (9%) Query: 29 IIGGNEVTPHSRPYMVLLSLD----RKTICAGALIAKDWVLTAAHCNLNKRS------QV 78 I+GG + T PY + C ++ +++ +TA HC Q+ Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 79 ILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKK 138 + G ++ E ++QI+ V K + +D + D+ LL+L N V + LP++ Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALPEQ 120 Query: 139 GDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCA 198 G V GWG T + D L++V + ++ + C I +M+CA Sbjct: 121 GHTATGD--VIVTGWGTTSEGGNTPDVLQKVTVPLVSDEDCRADY---GADEILDSMICA 175 Query: 199 GSLRGGRDSCNGDSGSPLLCEGV----FRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 G GG+DSC GDSG PL G+ S+G C P PGVY +S H++WI Sbjct: 176 GVPEGGKDSCQGDSGGPLAASDTGSTYLAGIVSWGY--GCARPGYPGVYTEVS-YHVDWI 232 Query: 255 IMT 257 Sbjct: 233 KAN 235 >1LTO-A nrPDB Length = 245 Score = 253 bits (647), Expect = 6e-68, Method: Composition-based stats. Identities = 73/245 (29%), Positives = 115/245 (46%), Gaps = 27/245 (11%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRK---TICAGALIAKDWVLTAAHCNLNK-----RSQVIL 80 I+GG E P+ V L + + C G+LI WVLTAAHC +V L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQL 60 Query: 81 GAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGD 140 + ++ Q++ V + +P + D+ LL+L E I+ V + LP + Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPASE 117 Query: 141 DVKPGTMCQVAGWGRTHNSASWSD--TLREVNITIIDRKVCNDRNHYNFN-----PVIGM 193 PG C V GWG N L++V + I++ +C+ + H +I Sbjct: 118 TFPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIIRD 177 Query: 194 NMVCAGSLRGGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKK 249 +M+CAG+ + RDSC GDSG PL+C+ + GV S+ + C P PG+Y ++ Sbjct: 178 DMLCAGNSQ--RDSCKGDSGGPLVCKVNGTWLQAGVVSW--DEGCAQPNRPGIYTRVT-Y 232 Query: 250 HLNWI 254 +L+WI Sbjct: 233 YLDWI 237 >1ELT-A nrPDB Length = 236 Score = 253 bits (646), Expect = 8e-68, Method: Composition-based stats. Identities = 71/241 (29%), Positives = 115/241 (47%), Gaps = 16/241 (6%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRK----TICAGALIAKDWVLTAAHCNLN-KRSQVILGAH 83 ++GG P+S P+ + L C G+LI + WV+TAAHC + + +V+LG H Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSARTWRVVLGEH 60 Query: 84 SITREEPTKQIMLVKKEFPYPCYDPATR--EGDLKLLQLMEKAKINKYVTILHLPKKGDD 141 ++ E +QIM V F + ++ D+ LL+L +A +N V + LP Sbjct: 61 NLNTNEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPSNQI 120 Query: 142 VKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSL 201 + C + GWG+T SD+L++ + +D C+ + + MVCAG Sbjct: 121 LPNNNPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSSSGWWG--STVKTTMVCAGG- 177 Query: 202 RGGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMT 257 G CNGDSG PL C+ GVTSF + C + P V+ +S +++W+ Sbjct: 178 -GANSGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSA-YISWMNGI 235 Query: 258 I 258 + Sbjct: 236 M 236 >1FUJ-A nrPDB Length = 221 Score = 252 bits (645), Expect = 8e-68, Method: Composition-based stats. Identities = 76/237 (32%), Positives = 118/237 (49%), Gaps = 22/237 (9%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRK---TICAGALIAKDWVLTAAHCNLN---KRSQVILGA 82 I+GG+E PHSRPYM L + C G LI +VLTAAHC + + V+LGA Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 60 Query: 83 HSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDV 142 H++ +EPT+Q V + F YD + D+ L+QL A ++ V + LP++ V Sbjct: 61 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDILLIQLSSPANLSASVATVQLPQQDQPV 119 Query: 143 KPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 202 GT C GWGR + L+E+N+T++ C + +C R Sbjct: 120 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT-FFCR------------PHNICTFVPR 166 Query: 203 GGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 C GDSG PL+C+G+ +G+ SF + C P + ++ +++WI T++ Sbjct: 167 RKAGICFGDSGGPLICDGIIQGIDSFVIW-GCATRLFPDFFTRVAL-YVDWIRSTLR 221 >1BDA-A nrPDB Length = 265 Score = 252 bits (645), Expect = 9e-68, Method: Composition-based stats. Identities = 71/257 (27%), Positives = 115/257 (44%), Gaps = 30/257 (11%) Query: 28 KIIGGNEVTPHSRPYMVLLSLDRK------TICAGALIAKDWVLTAAHCNLNKRS----Q 77 +I GG S P+ + + +C G LI+ W+L+AAHC + Sbjct: 13 RIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLT 72 Query: 78 VILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEK----AKINKYVTIL 133 VILG +Q V+K + +D T + D+ LLQL A+ + V + Sbjct: 73 VILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTV 132 Query: 134 HLPKKGDDVKPGTMCQVAGWGRTHNSAS-WSDTLREVNITIIDRKVCNDRNHYNFNPVIG 192 LP + T C+++G+G+ + +S+ L+E ++ + C + N + Sbjct: 133 CLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTS--QHLLNRTVT 190 Query: 193 MNMVCAGSLRGG------RDSCNGDSGSPLLCEG----VFRGVTSFGLENKCGDPRGPGV 242 NM+CAG R G D+C GDSG PL+C G+ S+GL CG PGV Sbjct: 191 DNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGL--GCGQKDVPGV 248 Query: 243 YILLSKKHLNWIIMTIK 259 Y ++ +L+WI ++ Sbjct: 249 YTKVT-NYLDWIRDNMR 264 >2AIQ-A nrPDB Length = 231 Score = 252 bits (645), Expect = 1e-67, Method: Composition-based stats. Identities = 73/234 (31%), Positives = 117/234 (50%), Gaps = 13/234 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITR- 87 +IGG+E + ++ L ++C G LI ++WVLTA HC+ ++ LG H++ Sbjct: 1 VIGGDECNINEHRFLA-LVYANGSLCGGTLINQEWVLTARHCDRG-NMRIYLGMHNLKVL 58 Query: 88 EEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTM 147 + + +K F + + D+ L++L + + ++ L LP V G++ Sbjct: 59 NKDALRRFPKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPSNPPSV--GSV 116 Query: 148 CQVAGWGR-THNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRD 206 C++ GWG T +A+ D NI I+D VC + +CAG L GG+D Sbjct: 117 CRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAYKG-----LAATTLCAGILEGGKD 171 Query: 207 SCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 +C GDSG PL+C G F+G+ S G N C PR PG+Y + + +WI I G Sbjct: 172 TCKGDSGGPLICNGQFQGILSVG-GNPCAQPRKPGIYTKVFD-YTDWIQSIISG 223 >4E7N-A nrPDB Length = 238 Score = 251 bits (642), Expect = 2e-67, Method: Composition-based stats. Identities = 75/236 (31%), Positives = 119/236 (50%), Gaps = 10/236 (4%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRK--TICAGALIAKDWVLTAAHCNLNKRSQVILGAHSIT 86 IIGG+E + ++V L R C G LI ++WVLTAAHC+ K ++ LG HS Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRTLFCGGTLINQEWVLTAAHCDR-KNFRIKLGMHSKK 59 Query: 87 REEPTKQIMLVKKEFPY-PCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 +Q + K++F + + D+ L++L K +K++ G Sbjct: 60 VPNEDEQTRVPKEKFFCLSSKNYTLWDKDIMLIRLDSPVKNSKHIAPFS--LPSSPPSVG 117 Query: 146 TMCQVAGWGRTHNS-ASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 204 ++C++ GWGR + ++ D VNI +++ ++C F +CAG L GG Sbjct: 118 SVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYP-EFELPATSRTLCAGILEGG 176 Query: 205 RDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 +D+C GDSG PL+C G F+G+ S+G ++ C P P Y + HL+WI I G Sbjct: 177 KDTCKGDSGGPLICNGQFQGIASWG-DDPCAQPHKPAAYTKVFD-HLDWIENIIAG 230 >1YC0-A nrPDB Length = 283 Score = 250 bits (640), Expect = 4e-67, Method: Composition-based stats. Identities = 79/246 (32%), Positives = 124/246 (50%), Gaps = 20/246 (8%) Query: 28 KIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQ----VILGAH 83 +IIGG+ P S P++ + + + CAG+L+ WV++AAHC + + V+LG H Sbjct: 35 RIIGGSSSLPGSHPWLAAIYI-GDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQH 93 Query: 84 SITREEPTKQIMLVKKEFPYPCYDPAT-REGDLKLLQLMEK----AKINKYVTILHLPKK 138 R Q ++K PY Y + DL L++L +K A +++V + LP+ Sbjct: 94 FFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEP 153 Query: 139 GDDVKPGTMCQVAGWGRTHNSAS-WSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVC 197 G G CQ+AGWG + S +S +LRE + ++ C+ Y + I NM+C Sbjct: 154 GSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGAD--ISPNMLC 211 Query: 198 AGSLRGGRDSCNGDSGSPLLCEG----VFRGVTSFGLENKCGDPRGPGVYILLSKKHLNW 253 AG D+C GDSG PL CE G+ S+G + CG PGVY ++ +++W Sbjct: 212 AGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWG--DGCGRLHKPGVYTRVA-NYVDW 268 Query: 254 IIMTIK 259 I I+ Sbjct: 269 INDRIR 274 >2BDH-A nrPDB Length = 223 Score = 250 bits (638), Expect = 6e-67, Method: Composition-based stats. Identities = 77/233 (33%), Positives = 121/233 (51%), Gaps = 11/233 (4%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSIT-R 87 II G + +PHS+P+ L ++ + C+G L+ WVL+AAHC N + LG HS+ Sbjct: 1 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNS-YTIGLGLHSLEAD 59 Query: 88 EEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTM 147 +EP Q++ +P Y+ DL L++L E + + + + + G Sbjct: 60 QEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT--AGNS 117 Query: 148 CQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDS 207 C V+GWG N L+ VN++++ +VC+ ++P+ +M CAG + +DS Sbjct: 118 CLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCSKL----YDPLYHPSMFCAGGGQDQKDS 172 Query: 208 CNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 CNGDSG PL+C G +G+ SFG + CG PGVY L K WI T++ Sbjct: 173 CNGDSGGPLICNGYLQGLVSFG-KAPCGQVGVPGVYTNLC-KFTEWIEKTVQA 223 >1KYN-A nrPDB Length = 235 Score = 250 bits (638), Expect = 6e-67, Method: Composition-based stats. Identities = 87/234 (37%), Positives = 129/234 (55%), Gaps = 14/234 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLD---RKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSI 85 IIGG E PHSRPYM L + ++ C G L+ +D+VLTAAHC V LGAH+I Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHC-WGSNINVTLGAHNI 59 Query: 86 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 R E T+Q + ++ +P Y+ T + D+ LLQL + + N+ V + LP+ + ++PG Sbjct: 60 QRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPG 119 Query: 146 TMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 205 T+C VAGWGR + +DTLREV + + + C R +++P +C G R + Sbjct: 120 TLCTVAGWGRV-SMRRGTDTLREVQLRVQRDRQC-LRIFGSYDP---RRQICVGDRRERK 174 Query: 206 DSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 + GDSG PLLC V G+ S+G + P V+ +S L WI T++ Sbjct: 175 AAFKGDSGGPLLCNNVAHGIVSYGKSSG----VPPEVFTRVS-SFLPWIRTTMR 223 >2RDL-A nrPDB Length = 226 Score = 250 bits (638), Expect = 6e-67, Method: Composition-based stats. Identities = 86/235 (36%), Positives = 133/235 (56%), Gaps = 15/235 (6%) Query: 29 IIGGNEVTPHSRPYMVLLSL----DRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHS 84 IIGG E PH+RPYM L + + + C+G LI +++V+TAAHC + V+LGAH+ Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHC-AGRSITVLLGAHN 59 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKP 144 +E T Q + V+K+FP+P YD D+ LL+L EKA + V L + K + + P Sbjct: 60 KKVKEDTWQKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPISAKSNSIPP 119 Query: 145 GTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 204 G +C+ GWGRT+ + SDTL+EV + I+D + C ++ P +C G+ + Sbjct: 120 GRVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQACKHFEDFHQEP-----QLCVGNPKKI 174 Query: 205 RDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 R+ GDSG PLLC G+ +G+ S+ L N + P V+ +S + WI ++ Sbjct: 175 RNVYKGDSGGPLLCAGIAQGIASYVLRN----AKPPSVFTRIS-HYRPWINKILR 224 >1A5I-A nrPDB Length = 265 Score = 250 bits (638), Expect = 6e-67, Method: Composition-based stats. Identities = 74/253 (29%), Positives = 119/253 (47%), Gaps = 30/253 (11%) Query: 31 GGNEVTPHSRPYMVLL------SLDRKTICAGALIAKDWVLTAAHCNL----NKRSQVIL 80 GG S P+ + S + +C G LI+ WVLTAAHC + +V+L Sbjct: 16 GGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVVL 75 Query: 81 GAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEK----AKINKYVTILHLP 136 G + +Q VKK + +D T D+ LLQL A+ + V + LP Sbjct: 76 GRTYRVKPGEEEQTFKVKKYIVHKEFDDDTYNNDIALLQLKSDSPQCAQESDSVRAICLP 135 Query: 137 KKGDDVKPGTMCQVAGWGRTHNSAS-WSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNM 195 + + T C+++G+G+ +S+ +S+ L+E ++ + C + + FN + NM Sbjct: 136 EANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCAPK--FLFNKTVTNNM 193 Query: 196 VCAGSLRGGR------DSCNGDSGSPLLCEG----VFRGVTSFGLENKCGDPRGPGVYIL 245 +CAG R G D+C GDSG PL+C G+ S+G+ CG+ PGVY Sbjct: 194 LCAGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWGV--GCGEKDVPGVYTK 251 Query: 246 LSKKHLNWIIMTI 258 ++ +L WI + Sbjct: 252 VT-NYLGWIRDNM 263 >1BQY-A nrPDB Length = 234 Score = 248 bits (634), Expect = 2e-66, Method: Composition-based stats. Identities = 75/234 (32%), Positives = 120/234 (51%), Gaps = 10/234 (4%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 + GG+E + +V+L +C G LI +DWV+TAAHC+ N Q++ G HS Sbjct: 1 VFGGDECNINEHRSLVVLFNSNGFLCGGTLINQDWVVTAAHCDSN-NFQLLFGVHSKKIL 59 Query: 89 EPTKQIMLVKKEFPYPCYDPAT-REGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTM 147 +Q K++F P + D+ L++L ++++ L G++ Sbjct: 60 NEDEQTRDPKEKFFCPNRKKDDEVDKDIMLIKLDSSVSNSEHIAPLS--LPSSPPSVGSV 117 Query: 148 CQVAGWGRTHNSAS-WSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRD 206 C++ GWG+T + + D NI I+D VC + + +CAG L+GGRD Sbjct: 118 CRIMGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSW---RQVANTTLCAGILQGGRD 174 Query: 207 SCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 +C+ DSG PL+C G+F+G+ S+G + CG P PGVY + +L+WI I G Sbjct: 175 TCHFDSGGPLICNGIFQGIVSWG-GHPCGQPGEPGVYTKVFD-YLDWIKSIIAG 226 >4Z6A-H nrPDB Length = 249 Score = 248 bits (633), Expect = 2e-66, Method: Composition-based stats. Identities = 63/242 (26%), Positives = 105/242 (43%), Gaps = 18/242 (7%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCN----LNKRSQVILGAHS 84 I+GG P+ VLL ++ +C G LI WV++AAHC + +LG H Sbjct: 1 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHD 60 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKK---GDD 141 ++ + +Q V + Y P T D+ LL+L + + +V L LP++ Sbjct: 61 LSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERT 120 Query: 142 VKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSL 201 + V+GWG+ + + + L +N+ + + C + I M CAG Sbjct: 121 LAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEAS----YPGKITEYMFCAGYS 176 Query: 202 RGGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMT 257 G +DSC GDSG P G+ S+G C GVY +S +++ W+ Sbjct: 177 DGSKDSCKGDSGGPHATHYRGTWYLTGIVSWG--QGCATVGHFGVYTRVS-QYIEWLQKL 233 Query: 258 IK 259 ++ Sbjct: 234 MR 235 >1Q3X-A nrPDB Length = 328 Score = 248 bits (633), Expect = 2e-66, Method: Composition-based stats. Identities = 75/264 (28%), Positives = 116/264 (43%), Gaps = 20/264 (7%) Query: 10 SSLSVVVSLLLIPEDVCE-KIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAA 68 SL V + + +I GG + P P+ VL+ T AGAL+ +WVLTAA Sbjct: 67 KSLPVCEPVCGLSARTTGGRIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAA 124 Query: 69 HCNLNKRSQVI---LGAHSITREEPTKQIMLVKKEFPYPCY-DPATREGDLKLLQLMEKA 124 H ++ + ++ R P + F + Y A + D+ L++L K Sbjct: 125 HAVYEQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKV 184 Query: 125 KINKYVTILHLPKKGDD--VKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDR 182 IN +T + LP+K + ++ + +GWG T + L V+I I+D + C Sbjct: 185 VINSNITPICLPRKEAESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQKCTAA 243 Query: 183 NHYNFNP--VIGMNMVCAGSLRGGRDSCNGDSGSPLLC------EGVFRGVTSFGLENKC 234 P + NM+CAG GG+DSC GDSG L+ G+ S+G N C Sbjct: 244 YEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMN-C 302 Query: 235 GDPRGPGVYILLSKKHLNWIIMTI 258 G+ GVY + ++ WI I Sbjct: 303 GEAGQYGVYTKV-INYIPWIENII 325 >1OP0-A nrPDB Length = 234 Score = 246 bits (629), Expect = 6e-66, Method: Composition-based stats. Identities = 71/235 (30%), Positives = 117/235 (49%), Gaps = 12/235 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 +IGGNE + ++V C G LI +WV+TAAHC+ + Q+ LG HS Sbjct: 1 VIGGNECDINEHRFLVAFFNTTGFFCGGTLINPEWVVTAAHCD-STDFQMQLGVHSKKVL 59 Query: 89 EPTKQIMLVKKEFPYPCY-DPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTM 147 +Q K++F P + + D+ L++L + +K++ L G++ Sbjct: 60 NEDEQTRNPKEKFICPNKNNNEVLDKDIMLIKLDKPISNSKHIAPLS--LPSSPPSVGSV 117 Query: 148 CQVAGWGR-THNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGM-NMVCAGSLRGGR 205 C++ GWG T ++ D NI ++D VC + ++ +CAG ++GG+ Sbjct: 118 CRIMGWGSITPVKETFPDVPYCANINLLDHAVCQA----GYPELLAEYRTLCAGIVQGGK 173 Query: 206 DSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 D+C GDSG PL+C G F+G+ S+G + CG PG+Y + + +WI I G Sbjct: 174 DTCGGDSGGPLICNGQFQGIVSYGA-HPCGQGPKPGIYTNVFD-YTDWIQRNIAG 226 >2R0L-A nrPDB Length = 248 Score = 246 bits (628), Expect = 7e-66, Method: Composition-based stats. Identities = 79/245 (32%), Positives = 123/245 (50%), Gaps = 20/245 (8%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQ----VILGAHS 84 IIGG+ P S P++ + + + CAG+L+ WV++AAHC + + V+LG H Sbjct: 1 IIGGSSSLPGSHPWLAAIYI-GDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHF 59 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPAT-REGDLKLLQLMEK----AKINKYVTILHLPKKG 139 R Q ++K PY Y + DL L++L +K A +++V + LP+ G Sbjct: 60 FNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPG 119 Query: 140 DDVKPGTMCQVAGWGRTHNSAS-WSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCA 198 G CQ+AGWG + S +S +LRE + ++ C+ Y + I NM+CA Sbjct: 120 STFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGAD--ISPNMLCA 177 Query: 199 GSLRGGRDSCNGDSGSPLLCEG----VFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 G D+C GDSG PL CE G+ S+G + CG PGVY ++ +++WI Sbjct: 178 GYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWG--DGCGRLHKPGVYTRVA-NYVDWI 234 Query: 255 IMTIK 259 I+ Sbjct: 235 NDRIR 239 >4Q7Y-A nrPDB Length = 250 Score = 245 bits (627), Expect = 1e-65, Method: Composition-based stats. Identities = 83/236 (35%), Positives = 121/236 (51%), Gaps = 11/236 (4%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQ---VILGAHSI 85 IIGG+EVTPHSRPYM + + C G L+ WV++AAHC ++ + V+LGAH + Sbjct: 1 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 60 Query: 86 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVK-P 144 + EPT+Q+ + +P Y P T D+ LL+L A + V +L LP + Sbjct: 61 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRARPPTA 120 Query: 145 GTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 204 GT C+VAGWG + L E + ++D VCN + + + M+C S Sbjct: 121 GTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSS----WKGHLTLTMLCTRSGDSH 176 Query: 205 RDS-CNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 R C+ DSG PL+C G+ SF CGDP+ P VY +S + WI ++ Sbjct: 177 RRGFCSADSGGPLVCRNRAHGLVSFS-GLWCGDPKTPDVYTQVSA-FVAWIWDVVR 230 >1FON-A nrPDB Length = 240 Score = 245 bits (626), Expect = 1e-65, Method: Composition-based stats. Identities = 72/243 (29%), Positives = 115/243 (47%), Gaps = 19/243 (7%) Query: 31 GGNEVTPHSRPYMVLLSLDR----KTICAGALIAKDWVLTAAHCNLNKR-SQVILGAHSI 85 G + P+S + V L ++ C G+LIA DWV+TA HC R QV+LG + Sbjct: 1 NGEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSRTYQVVLGEYDR 60 Query: 86 TREEPTKQIMLVKK--EFPYPCYDPA--TREGDLKLLQLMEKAKINKYVTILHLPKKGDD 141 + E ++Q++ + F +P ++ D+ L++L A++ V + +LP GD Sbjct: 61 SVLEGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPAGDI 120 Query: 142 VKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSL 201 + C ++GWGR + D L++ + +D + C+ + + + MVCAG Sbjct: 121 LPNEAPCYISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQWDWWGI--TVKKTMVCAGGD 178 Query: 202 RGGRDSCNGDSGSPLLC-----EGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIM 256 R CNGDSG PL C GVTSF C + P V+ +S ++WI Sbjct: 179 T--RSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSA-FIDWIDE 235 Query: 257 TIK 259 TI Sbjct: 236 TIA 238 >4XDE-A nrPDB Length = 257 Score = 245 bits (625), Expect = 2e-65, Method: Composition-based stats. Identities = 78/245 (31%), Positives = 117/245 (47%), Gaps = 23/245 (9%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKR----SQVILGAHS 84 ++GG + PY+ L + CAG+LIA WVLTAAHC ++ V+LG Sbjct: 3 VVGGLVALRGAHPYIAALYWGH-SFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQER 61 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAK-----INKYVTILHLPKKG 139 Q + V+ + + P + + DL LL+L E A ++ YV + LP Sbjct: 62 RNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSLPSGA 121 Query: 140 DDVKPGTMCQVAGWGRTHNS-ASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCA 198 T+CQVAGWG ++ L+E + + + C+ + + I M+CA Sbjct: 122 ARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHG--SSILPGMLCA 179 Query: 199 GSLRGGRDSCNGDSGSPLLCEG-------VFRGVTSFGLENKCGDPRGPGVYILLSKKHL 251 G L GG D+C GDSG PL+CE +G+ S+G + CGD PGVY ++ +L Sbjct: 180 GFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWG--SGCGDRNKPGVYTDVA-YYL 236 Query: 252 NWIIM 256 WI Sbjct: 237 AWIRE 241 >1FIZ-A nrPDB Length = 263 Score = 245 bits (625), Expect = 2e-65, Method: Composition-based stats. Identities = 79/253 (31%), Positives = 114/253 (45%), Gaps = 28/253 (11%) Query: 29 IIGGNEVTPHSRPYMVLLSL------DRKTICAGALIAKDWVLTAAHCNLNKR----SQV 78 ++GG P + P+MV L + R C G L+ WVLTAAHC NK+ ++ Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 79 ILGAHSITREE-----PTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTIL 133 I GA+ + P Q V++ + Y D+ L+++ ++ Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGPG 120 Query: 134 HLPK-KGDDVKPGTMCQVAGWGRTHNSA-SWSDTLREVNITIIDRKVCNDRNHYNFNPVI 191 LP+ K + C V GWG S TL+E + +ID ++CN YN I Sbjct: 121 CLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGR--I 178 Query: 192 GMNMVCAGSLRGGRDSCNGDSGSPLLCEG------VFRGVTSFGLENKCGDPRGPGVYIL 245 VCAG RG D+C GDSG PL+C V G+TS+G+ C + PGVY Sbjct: 179 RSTNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGV--GCARAKRPGVYTS 236 Query: 246 LSKKHLNWIIMTI 258 + +LNWI I Sbjct: 237 -TWPYLNWIASKI 248 >1ZJK-A nrPDB Length = 403 Score = 245 bits (625), Expect = 2e-65, Method: Composition-based stats. Identities = 75/264 (28%), Positives = 116/264 (43%), Gaps = 20/264 (7%) Query: 10 SSLSVVVSLLLIPEDVCE-KIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAA 68 SL V + + +I GG + P P+ VL+ T AGAL+ +WVLTAA Sbjct: 142 KSLPVCEPVCGLSARTTGGQIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAA 199 Query: 69 HCNLNKRSQVI---LGAHSITREEPTKQIMLVKKEFPYPCY-DPATREGDLKLLQLMEKA 124 H ++ + ++ R P + F + Y A + D+ L++L K Sbjct: 200 HAVYEQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKV 259 Query: 125 KINKYVTILHLPKKGDD--VKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDR 182 IN +T + LP+K + ++ + +GWG T + L V+I I+D + C Sbjct: 260 VINSNITPICLPRKEAESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQKCTAA 318 Query: 183 NHYNFNP--VIGMNMVCAGSLRGGRDSCNGDSGSPLLC------EGVFRGVTSFGLENKC 234 P + NM+CAG GG+DSC GDSG L+ G+ S+G N C Sbjct: 319 YEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMN-C 377 Query: 235 GDPRGPGVYILLSKKHLNWIIMTI 258 G+ GVY + ++ WI I Sbjct: 378 GEAGQYGVYTKV-INYIPWIENII 400 >3S9B-A nrPDB Length = 234 Score = 244 bits (624), Expect = 2e-65, Method: Composition-based stats. Identities = 75/235 (31%), Positives = 118/235 (50%), Gaps = 12/235 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTI--CAGALIAKDWVLTAAHCNLNKRSQVILGAHSIT 86 ++GG+E + P++V L + CAGALI ++WVLTAAHC+ + ++ LG HS Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIHCAGALINREWVLTAAHCDR-RNIRIKLGMHSKN 59 Query: 87 REEPTKQIMLVK-KEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 +QI + + K F P + D+ L++L + ++ + LP + V G Sbjct: 60 IRNEDEQIRVPRGKYFCLNTKFPNGLDKDIMLIRLRRPVTYSTHIAPVSLPSRSRGV--G 117 Query: 146 TMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 205 + C++ GWG+ + ++ D NI I+ K C + +CAG L+GGR Sbjct: 118 SRCRIMGWGKISTT-TYPDVPHCTNIFIVKHKWCEPLYPWVPAD---SRTLCAGILKGGR 173 Query: 206 DSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 D+C+GDSG PL+C G G+ + G CG P VY + + NWI I G Sbjct: 174 DTCHGDSGGPLICNGEMHGIVA-GGSEPCGQHLKPAVYTKVFD-YNNWIQSIIAG 226 >3F6U-H nrPDB Length = 240 Score = 244 bits (624), Expect = 3e-65, Method: Composition-based stats. Identities = 71/245 (28%), Positives = 116/245 (47%), Gaps = 22/245 (8%) Query: 30 IGGNEVTPHSRPYMV-LLSLDRKTICAGALIAKDWVLTAAHC-NLNKRSQVILGAHSITR 87 I G P+ V LL +K C LI WVLTAAHC + +K+ V LG + + R Sbjct: 2 IDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLRR 61 Query: 88 EEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKG----DDVK 143 E + + +K+ F +P Y +T + D+ LL L + A +++ + + LP G + + Sbjct: 62 WEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQ 121 Query: 144 PGTMCQVAGWGRTHNSASWSD-----TLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCA 198 G V GWG + + L + I ++ C++ + ++ NM+CA Sbjct: 122 AGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVM----SNMVSENMLCA 177 Query: 199 GSLRGGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 G L +D+C GDSG P++ G+ S+G CG GVY +S ++L+WI Sbjct: 178 GILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWG--EGCGLLHNYGVYTKVS-RYLDWI 234 Query: 255 IMTIK 259 I+ Sbjct: 235 HGHIR 239 >3S69-A nrPDB Length = 234 Score = 243 bits (622), Expect = 4e-65, Method: Composition-based stats. Identities = 73/235 (31%), Positives = 116/235 (49%), Gaps = 12/235 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 +IGG+E + +V C+G LI ++WVLTAAHC+ N Q+ LG HS Sbjct: 1 VIGGDECNINEHRSLVAFFNSTGFFCSGTLINEEWVLTAAHCD-NTNFQMKLGVHSKKVL 59 Query: 89 EPTKQIMLVKKEFPYPC-YDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTM 147 +Q K++F P + + D+ L++L + ++++ + L G++ Sbjct: 60 NEDEQTRNPKEKFICPNKKNDEVLDKDIMLIKLDSRVSNSEHI--VPLSLPSSPPSVGSV 117 Query: 148 CQVAGWGR-THNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGM-NMVCAGSLRGGR 205 C + GWG T ++ D I ++D VC + ++ +CAG L GG+ Sbjct: 118 CHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQA----GYPELLTEYRTLCAGILEGGK 173 Query: 206 DSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 D+C GDSG PL+C G F+G+ SFG + CG PGVY + + +WI I G Sbjct: 174 DTCGGDSGGPLICNGQFQGIVSFGA-HPCGQGLKPGVYTKVFD-YNHWIQSIIAG 226 >2ZKS-A nrPDB Length = 240 Score = 242 bits (619), Expect = 9e-65, Method: Composition-based stats. Identities = 86/234 (36%), Positives = 122/234 (52%), Gaps = 12/234 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNK--RSQVILGAHSIT 86 IIGG EV PHSRPYM L + +C G L+ WVLTAAHC + + +++LG H++ Sbjct: 1 IIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLGLHTLD 60 Query: 87 REEPTKQIMLVKKEFPYPCYDP-ATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 T +K +P Y P E DL LLQL K K ++ + L LP K V G Sbjct: 61 SPGLT---FHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQVVAAG 117 Query: 146 TMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 205 T C +AGWG TH S LRE+++ ++D ++CN+ +N + + +MVC + + Sbjct: 118 TRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGS--LSPSMVCLAADSKDQ 175 Query: 206 DSCNGDSGSPLLC--EGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMT 257 C GDSG PL+C V GV SF C D P V ++ +++WI Sbjct: 176 APCKGDSGGPLVCGKGRVLAGVLSFS-SRVCTDIFKPPVATAVAP-YVSWIRKV 227 >4IW4-E nrPDB Length = 279 Score = 242 bits (619), Expect = 1e-64, Method: Composition-based stats. Identities = 68/268 (25%), Positives = 118/268 (44%), Gaps = 40/268 (14%) Query: 29 IIGGNEVTPHSRPYMVLLSLDR-------KTICAGALIAKDWVLTAAHCNLNKR------ 75 IIGG P P+ L+ ++ K +GAL++ W+LTAAH ++R Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 76 ------SQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKY 129 V LG H + R++ + +P ++ D+ L+QL E + + Sbjct: 61 PVSKEHVTVYLGLHDV-RDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPH 119 Query: 130 VTILHLPK-KGDDVKPGTMCQVAGWGRTHNS-----------ASWSDTLREVNITIIDRK 177 V + LP+ + + P + VAGWG ++ + + SD L+ V + ++ Sbjct: 120 VMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHA 179 Query: 178 VCNDRNH-YNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLL------CEGVFRGVTSFGL 230 C + N + NM CAG GG+D+C GDSG + V +G+ S+G Sbjct: 180 ECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWGG 239 Query: 231 ENKCGDPRGPGVYILLSKKHLNWIIMTI 258 +CG + GVY +S +++W+ + Sbjct: 240 PEECGSKQVYGVYTKVS-NYVDWVWEQM 266 >2OCV-B nrPDB Length = 259 Score = 242 bits (618), Expect = 1e-64, Method: Composition-based stats. Identities = 70/261 (26%), Positives = 112/261 (42%), Gaps = 38/261 (14%) Query: 29 IIGGNEVTPHSRPYMVLLSLD--RKTICAGALIAKDWVLTAAHCNLNKRSQ--------- 77 I+ G + P+ V+L ++ +C +LI+ WVLTAAHC L Sbjct: 1 IVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLL 60 Query: 78 VILGAHSITREEPT-KQIMLVKKEFPYPCYD-PATREGDLKLLQLMEKAKINKYVTILHL 135 V +G HS TR E ++I +++K + +P Y+ + D+ LL+L + + Y+ + L Sbjct: 61 VRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCL 120 Query: 136 PKKG---DDVKPGTMCQVAGWGRTHNSASW------SDTLREVNITIIDRKVCNDRNHYN 186 P K ++ G +V GWG + + L+ VN+ I++R VC Sbjct: 121 PDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRIR 180 Query: 187 FNPVIGMNMVCAG---SLRGGRDSCNGDSGSPLLCE------GVFRGVTSFGLENKCGDP 237 I NM CAG + D+C GDSG P + + G+ S+G C Sbjct: 181 ----ITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG--EGCDRK 234 Query: 238 RGPGVYILLSKKHLNWIIMTI 258 G Y + + WI I Sbjct: 235 GKYGFYTHVFRL-KAWIQKVI 254 >5LHN-A nrPDB Length = 247 Score = 241 bits (615), Expect = 3e-64, Method: Composition-based stats. Identities = 64/251 (25%), Positives = 108/251 (43%), Gaps = 26/251 (10%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRK------TICAGALIAKDWVLTAAHCNL----NKRSQV 78 I+GG ++P+ + K C G+LI+ WV +AAHC + + V Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 79 ILGAHSITREEPTKQIMLVKKEFPYPCY--DPATREGDLKLLQLMEK----AKINKYVTI 132 LG + P + V++ + Y D D+ LL++ A+ ++ + Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQT 120 Query: 133 LHLPKKGDDVKPGTMCQVAGWGRTHNSAS-WSDTLREVNITIIDRKVCNDRNHYNFNPVI 191 + LP + D G+ C++ G+G+ S + L+ + ++ + C ++Y I Sbjct: 121 IALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQPHYYG--SEI 178 Query: 192 GMNMVCAGSLRGGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLS 247 M+CA DSC GDSG PL+C G+ S+G C + PGVY +S Sbjct: 179 NYKMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWG--RGCAEKNKPGVYTRVS 236 Query: 248 KKHLNWIIMTI 258 L+WI I Sbjct: 237 -HFLDWIQSHI 246 >1FIW-A nrPDB Length = 290 Score = 241 bits (615), Expect = 3e-64, Method: Composition-based stats. Identities = 78/253 (30%), Positives = 118/253 (46%), Gaps = 28/253 (11%) Query: 29 IIGGNEVTPHSRPYMVLLSL------DRKTICAGALIAKDWVLTAAHCNLNKR----SQV 78 IIGG + + P+MV L + R +C G+L+ W+LTAAHC K+ ++ Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 79 ILGAHSITRE-----EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTIL 133 I GA + +P Q V+K + Y ++ D+ L+++ ++ Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGPG 120 Query: 134 HLPK-KGDDVKPGTMCQVAGWGRTHNSA-SWSDTLREVNITIIDRKVCNDRNHYNFNPVI 191 LP+ + + C VAGWG +A S L+E + +ID +CN YN I Sbjct: 121 CLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGR--I 178 Query: 192 GMNMVCAGSLRGGRDSCNGDSGSPLLCEG------VFRGVTSFGLENKCGDPRGPGVYIL 245 VCAG G D+C GDSG PL+C+ V G+TS+G+ C + PGVY Sbjct: 179 RSTNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGV--GCARAKRPGVYTS 236 Query: 246 LSKKHLNWIIMTI 258 + +LNWI I Sbjct: 237 -TWSYLNWIASKI 248 >1VR1-H nrPDB Length = 261 Score = 241 bits (615), Expect = 3e-64, Method: Composition-based stats. Identities = 69/265 (26%), Positives = 113/265 (42%), Gaps = 42/265 (15%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRK------TICAGALIAKDWVLTAAHCNLNKRSQ----- 77 I+ G++ P+ V+L + +C +LI+ WVLTAAHC L Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 78 ----VILGAHSITREEPT-KQIMLVKKEFPYPCYD-PATREGDLKLLQLMEKAKINKYVT 131 V +G HS TR E ++I +++K + +P Y+ + D+ L++L + + Y+ Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 120 Query: 132 ILHLPKK---GDDVKPGTMCQVAGWGRTHNSAS------WSDTLREVNITIIDRKVCNDR 182 + LP + ++ G +V GWG + + L+ VN+ I++R VC D Sbjct: 121 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDS 180 Query: 183 NHYNFNPVIGMNMVCAGS-LRGGR--DSCNGDSGSPLLCE------GVFRGVTSFGLENK 233 I NM CA G+ D+C GDSG P + + G+ S+G Sbjct: 181 TRIR----ITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG--EG 234 Query: 234 CGDPRGPGVYILLSKKHLNWIIMTI 258 C G Y + + WI I Sbjct: 235 CDRDGKYGFYTHVFRL-KKWIQKVI 258 >1ELV-A nrPDB Length = 333 Score = 240 bits (614), Expect = 3e-64, Method: Composition-based stats. Identities = 69/280 (24%), Positives = 119/280 (42%), Gaps = 37/280 (13%) Query: 6 RFLASSLSVVVSLLLIPEDVC---EKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKD 62 L L V + +P + ++IIGG++ + P+ V GALI + Sbjct: 57 EVLGPELPKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFF---DNPWAGGALINEY 113 Query: 63 WVLTAAHCN-LNKRSQVILGAHSITREEPTKQIML-VKKEFPYPCYD-------PATREG 113 WVLTAAH N+ + +G+ S+ K ML + F +P + + Sbjct: 114 WVLTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLAVPEGRTNFDN 173 Query: 114 DLKLLQLMEKAKINKYVTILHLP--KKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNI 171 D+ L++L + K+ V+ + LP ++ G + ++GWGRT + L+ + Sbjct: 174 DIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARL 232 Query: 172 TIIDRKVCND-----RNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEG------ 220 + + C + V NM+CAG G DSC GDSG + Sbjct: 233 PVAPLRKCKEVKVEKPTADAEAYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTK 291 Query: 221 -VFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 G+ S+G + CG G+Y + K +++WI+ T++ Sbjct: 292 FYAAGLVSWGPQ--CGT---YGLYTRV-KNYVDWIMKTMQ 325 >4DJZ-B nrPDB Length = 251 Score = 240 bits (614), Expect = 4e-64, Method: Composition-based stats. Identities = 73/253 (28%), Positives = 116/253 (45%), Gaps = 31/253 (12%) Query: 29 IIGGNEVTPHSRPYMVLLS-LDRKTICAGALIAKDWVLTAAHCNL--------------- 72 I G + P++ +LS L+ + C G+L+ W++TAAHC Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDSDL 60 Query: 73 --NKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYV 130 ++ILG H R + +Q + VK +P YDP T E D+ L++L+E +N +V Sbjct: 61 LSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLNAFV 120 Query: 131 TILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPV 190 + LP+ + G M V+GWG+ + +TL E+ I I+D C Sbjct: 121 MPICLPEGPQ--QEGAMVIVSGWGKQFLQ-RFPETLMEIEIPIVDHSTCQKAYA-PLKKK 176 Query: 191 IGMNMVCAGSLRGGRDSCNGDSGSPLLC------EGVFRGVTSFGLENKCGDPRGPGVYI 244 + +M+CAG GG+D+C GDSG P++ + G S+G + CG GVY Sbjct: 177 VTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWG--DDCGKKDRYGVYS 234 Query: 245 LLSKKHLNWIIMT 257 + +WI Sbjct: 235 YIHHN-KDWIQRV 246 >1SC8-U nrPDB Length = 262 Score = 240 bits (612), Expect = 6e-64, Method: Composition-based stats. Identities = 64/249 (25%), Positives = 113/249 (45%), Gaps = 25/249 (10%) Query: 28 KIIGGNEVTPHSRPYMVLLSLDRK-----TICAGALIAKDWVLTAAHCNLNKRSQ----V 78 KIIGG T ++P+ + + +C G+LI+ WV++A HC ++ + V Sbjct: 15 KIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIV 74 Query: 79 ILGAHSITREEPTKQIMLVKKEFPYPCYDPAT--REGDLKLLQLMEK----AKINKYVTI 132 LG + + V+ + Y T D+ LL++ K A+ ++ + Sbjct: 75 YLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQT 134 Query: 133 LHLPKKGDDVKPGTMCQVAGWGRTHNSAS-WSDTLREVNITIIDRKVCNDRNHYNFNPVI 191 + LP +D + GT C++ G+G+ +++ + + L+ + +I + C ++Y + Sbjct: 135 ISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYG--SEV 192 Query: 192 GMNMVCAGSLRGGRDSCNGDSGSPLLC----EGVFRGVTSFGLENKCGDPRGPGVYILLS 247 M+CA + DSC GDSG PL+C G+ S+G C PGVY +S Sbjct: 193 TTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWG--RGCALKDKPGVYTRVS 250 Query: 248 KKHLNWIIM 256 L WI Sbjct: 251 -HFLPWIRS 258 >1ETT-H nrPDB Length = 259 Score = 239 bits (611), Expect = 8e-64, Method: Composition-based stats. Identities = 72/261 (27%), Positives = 111/261 (42%), Gaps = 38/261 (14%) Query: 29 IIGGNEVTPHSRPYMVLLSLD--RKTICAGALIAKDWVLTAAHCNLNKRSQ--------- 77 I+ G + P+ V+L ++ +C +LI+ WVLTAAHC L Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 78 VILGAHSITREEPT-KQIMLVKKEFPYPCYD-PATREGDLKLLQLMEKAKINKYVTILHL 135 V +G HS TR E ++I ++ K + +P Y+ + D+ LL+L +++ Y+ + L Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCL 120 Query: 136 PKKGDDVK---PGTMCQVAGWGR------THNSASWSDTLREVNITIIDRKVCNDRNHYN 186 P K K G +V GWG T + L+ VN+ +++R VC Sbjct: 121 PDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKASTRIR 180 Query: 187 FNPVIGMNMVCAGSLRGG---RDSCNGDSGSPLLCE------GVFRGVTSFGLENKCGDP 237 I NM CAG G D+C GDSG P + + G+ S+G C Sbjct: 181 ----ITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWG--EGCDRD 234 Query: 238 RGPGVYILLSKKHLNWIIMTI 258 G Y + + WI I Sbjct: 235 GKYGFYTHVFRL-KKWIQKVI 254 >4FXG-H nrPDB Length = 242 Score = 237 bits (605), Expect = 4e-63, Method: Composition-based stats. Identities = 71/244 (29%), Positives = 110/244 (45%), Gaps = 19/244 (7%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVI---LGAHSI 85 I GG + P P+ VL+ T AGAL+ +WVLTAAH ++ + ++ Sbjct: 1 IYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGTL 58 Query: 86 TREEPTKQIMLVKKEFPYPCY-DPATREGDLKLLQLMEKAKINKYVTILHLPKKGDD--V 142 R P + F + Y A + D+ L++L K IN +T + LP+K + + Sbjct: 59 KRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAESFM 118 Query: 143 KPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNP--VIGMNMVCAGS 200 + + +GWG T + L V+I I+D + C P + NM+CAG Sbjct: 119 RTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANMLCAGL 177 Query: 201 LRGGRDSCNGDSGSPLLC------EGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 GG+DSC GD+G L+ G+ S+G N CG+ GVY + ++ WI Sbjct: 178 ESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMN-CGEAGQYGVYTKV-INYIPWI 235 Query: 255 IMTI 258 I Sbjct: 236 ENII 239 >1AZZ-A nrPDB Length = 226 Score = 235 bits (599), Expect = 2e-62, Method: Composition-based stats. Identities = 71/230 (30%), Positives = 112/230 (48%), Gaps = 12/230 (5%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRS-QVILGAHSITR 87 I+GG E P+S P+ L +D C G+LI+ +W+LTAAHC V+LGAH+I Sbjct: 1 IVGGVEAVPNSWPHQAALFIDDMYFCGGSLISPEWILTAAHCMDGAGFVDVVLGAHNIRE 60 Query: 88 EEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTM 147 +E T+ + + Y+ D+ +++L + + + LP DV GT+ Sbjct: 61 DEATQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPST--DVGVGTV 118 Query: 148 CQVAGWGRTHNSA-SWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRD 206 GWG +SA SD LR+V++ I+ C+ ++ +C GG+ Sbjct: 119 VTPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVY-----GIVTDGNICI-DSTGGKG 172 Query: 207 SCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIM 256 +CNGDSG PL G+ G+TSFG C + P + ++ L+WI Sbjct: 173 TCNGDSGGPLNYNGLTYGITSFGAAAGC-EAGYPDAFTRVT-YFLDWIQT 220 >4J1Y-A nrPDB Length = 397 Score = 234 bits (597), Expect = 3e-62, Method: Composition-based stats. Identities = 69/280 (24%), Positives = 118/280 (42%), Gaps = 37/280 (13%) Query: 6 RFLASSLSVVVSLLLIPEDVCE---KIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKD 62 L L V + +P + E + IGG++ + P+ V GALI + Sbjct: 121 EVLGPELPKCVPVCGVPREPFEEKARAIGGSDADIKNFPWQVFF---DNPWAGGALINEY 177 Query: 63 WVLTAAHCN-LNKRSQVILGAHSITREEPTKQIML-VKKEFPYPCYD-------PATREG 113 WVLTAAH N+ + +G+ S+ K ML + F +P + + Sbjct: 178 WVLTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDN 237 Query: 114 DLKLLQLMEKAKINKYVTILHLP--KKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNI 171 D+ L++L + K+ V+ + LP ++ G + ++GWGRT + L+ + Sbjct: 238 DIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARL 296 Query: 172 TIIDRKVCND-----RNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEG------ 220 + + C + V NM+CAG G DSC GDSG + Sbjct: 297 PVAPLRKCKEVKVEKPTADAEAYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTK 355 Query: 221 -VFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 G+ S+G + CG G+Y + K +++WI+ T++ Sbjct: 356 FYAAGLVSWGPQ--CGT---YGLYTRV-KNYVDWIMKTMQ 389 >5TO3-B nrPDB Length = 409 Score = 230 bits (586), Expect = 6e-61, Method: Composition-based stats. Identities = 70/261 (26%), Positives = 114/261 (43%), Gaps = 38/261 (14%) Query: 29 IIGGNEVTPHSRPYMVLLSLD--RKTICAGALIAKDWVLTAAHCNLNKRSQ--------- 77 I+ G++ P+ V+L ++ +C +LI+ WVLTAAHC L Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 78 VILGAHSITREEPT-KQIMLVKKEFPYPCYD-PATREGDLKLLQLMEKAKINKYVTILHL 135 V +G HS TR E ++I +++K + +P Y+ + D+ L++L + + Y+ + L Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL 120 Query: 136 PKK---GDDVKPGTMCQVAGWGRTHNSAS------WSDTLREVNITIIDRKVCNDRNHYN 186 P + ++ G +V GWG + + L+ VN+ I++R VC D Sbjct: 121 PDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIR 180 Query: 187 FNPVIGMNMVCAGS-LRGGR--DSCNGDSGSPLLCE------GVFRGVTSFGLENKCGDP 237 I NM CAG G+ D+C GDSG P + + G+ S G C Sbjct: 181 ----ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAGA--GCDRD 234 Query: 238 RGPGVYILLSKKHLNWIIMTI 258 G Y + + WI I Sbjct: 235 GKYGFYTHVFRL-KKWIQKVI 254 >1MD7-A nrPDB Length = 328 Score = 229 bits (585), Expect = 7e-61, Method: Composition-based stats. Identities = 66/272 (24%), Positives = 110/272 (40%), Gaps = 31/272 (11%) Query: 9 ASSLSVVVSLLLIPEDVC---EKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVL 65 + + + P + ++IIGG + + P+ V ++ + GAL+ W+L Sbjct: 67 GEKIPRCLPVCGKPVNPVEQRQRIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWIL 124 Query: 66 TAAHCNLNKRSQ--------VILGAHSITREEPTKQIMLVKKEFPYPCYDPA---TREGD 114 TAAH K + V LG H+ E +++ +P Y EGD Sbjct: 125 TAAHTLYPKEHEAQSNASLDVFLG-HTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGD 183 Query: 115 LKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITII 174 + LL+L + + + LP G M V+G+G + LR V + + Sbjct: 184 IALLELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEE--KIAHDLRFVRLPVA 241 Query: 175 DRKVC-NDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGS------PLLCEGVFRGVTS 227 + + C N N V NM CAG +D+C GD+G P V G+ S Sbjct: 242 NPQACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVS 301 Query: 228 FGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 +G+ G RG G Y + +++WI ++ Sbjct: 302 WGI----GCSRGYGFYTKV-LNYVDWIKKEME 328 >1GPZ-A nrPDB Length = 399 Score = 229 bits (585), Expect = 8e-61, Method: Composition-based stats. Identities = 67/272 (24%), Positives = 110/272 (40%), Gaps = 31/272 (11%) Query: 9 ASSLSVVVSLLLIPEDVC---EKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVL 65 + + + P + ++IIGG + + P+ V ++ + GAL+ W+L Sbjct: 135 GEKIPRCLPVCGKPVNPVEQRQQIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWIL 192 Query: 66 TAAHCNLNKRSQ--------VILGAHSITREEPTKQIMLVKKEFPYPCYDPA---TREGD 114 TAAH K + V LG H+ E +++ +P Y EGD Sbjct: 193 TAAHTLYPKEHEAQSNASLDVFLG-HTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGD 251 Query: 115 LKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITII 174 + LL+L + + + LP G M V+G+G + LR V + + Sbjct: 252 IALLELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEE--KIAHDLRFVRLPVA 309 Query: 175 DRKVC-NDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGS------PLLCEGVFRGVTS 227 + + C N N V NM CAG +D+C GDSG P V G+ S Sbjct: 310 NPQACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVS 369 Query: 228 FGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 +G+ G RG G Y + +++WI ++ Sbjct: 370 WGI----GCSRGYGFYTKV-LNYVDWIKKEME 396 >5LPF-A nrPDB Length = 234 Score = 229 bits (585), Expect = 9e-61, Method: Composition-based stats. Identities = 78/237 (32%), Positives = 113/237 (47%), Gaps = 20/237 (8%) Query: 32 GNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITREEPT 91 G+ S+P+ V L CAG L+ + WVLTAAHC NK +G + Sbjct: 7 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHC-GNKPLWARVGDDHLLLL-QG 64 Query: 92 KQIMLVKKEFPYPCYD--------PATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVK 143 +Q+ + +P Y T E DL LL+L + V L LP + + Sbjct: 65 EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRC--AQ 122 Query: 144 PGTMCQVAGWGRT-HNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 202 PG CQVAGWG T ++ L +ITI+ K C + V+ NM+CAG L Sbjct: 123 PGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVF----YPGVVTNNMICAG-LD 177 Query: 203 GGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 G+D C DSG PL+C+ +G+ S+G+ CG + P VY + K+++WI I+ Sbjct: 178 RGQDPCQSDSGGPLVCDETLQGILSWGVY-PCGSAQHPAVYTQIC-KYMSWINKVIR 232 >1AE5-A nrPDB Length = 225 Score = 225 bits (574), Expect = 2e-59, Method: Composition-based stats. Identities = 79/233 (33%), Positives = 108/233 (46%), Gaps = 19/233 (8%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRS---QVILGAHSI 85 I+GG + P P++ + + C GALI +V+TAA C ++ V+LGA+ + Sbjct: 1 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 60 Query: 86 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 R E + YDP DL LLQL +A + VTIL LP + V+ G Sbjct: 61 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 120 Query: 146 TMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 205 T CQVAGWG + S R VN+T+ C N VC G L Sbjct: 121 TRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR------------PNNVCTGVLTRRG 168 Query: 206 DSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 CNGD G+PL+CEG+ GV SF L CG GP + ++ +WI + Sbjct: 169 GICNGDGGTPLVCEGLAHGVASFSLG-PCGR--GPDFFTRVAL-FRDWIDGVL 217 >1PPF-E nrPDB Length = 218 Score = 222 bits (567), Expect = 1e-58, Method: Composition-based stats. Identities = 77/234 (32%), Positives = 117/234 (50%), Gaps = 19/234 (8%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHC---NLNKRSQVILGAHSI 85 I+GG PH+ P+MV L L C LIA ++V++AAHC + +V+LGAH++ Sbjct: 1 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 60 Query: 86 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 +R EPT+Q+ V++ F YDP D+ +LQL A IN V + LP +G + G Sbjct: 61 SRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 119 Query: 146 TMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 205 C GWG + + L+E+N+T++ +C N VC Sbjct: 120 VQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRSN------------VCTLVRGRQA 166 Query: 206 DSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 C GDSGSPL+C G+ G+ SF + C P + ++ + +NWI I+ Sbjct: 167 GVCFGDSGSPLVCNGLIHGIASF-VRGGCASGLYPDAFAPVA-QFVNWIDSIIQ 218 >5UBM-A nrPDB Length = 252 Score = 221 bits (564), Expect = 2e-58, Method: Composition-based stats. Identities = 65/255 (25%), Positives = 111/255 (43%), Gaps = 34/255 (13%) Query: 28 KIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCN-LNKRSQVILGAHSIT 86 +IIGG++ + P+ V GALI + WVLTAAH N+ + +G+ S+ Sbjct: 1 RIIGGSDADIKNFPWQVFF---DNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQ 57 Query: 87 REEPTKQIML-VKKEFPYPCYD-------PATREGDLKLLQLMEKAKINKYVTILHLP-- 136 K ML + F +P + + D+ L++L + K+ V+ + LP Sbjct: 58 TSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGT 117 Query: 137 KKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCND-----RNHYNFNPVI 191 ++ G + ++GWGRT + L+ + + + C + V Sbjct: 118 SSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPVAPLRKCKEVKVEKPTADAEAYVF 176 Query: 192 GMNMVCAGSLRGGRDSCNGDSGSPLLCEG-------VFRGVTSFGLENKCGDPRGPGVYI 244 NM+CAG G DSC GDSG + G+ S+G + CG G+Y Sbjct: 177 TPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQ--CGT---YGLYT 230 Query: 245 LLSKKHLNWIIMTIK 259 + K +++WI+ T++ Sbjct: 231 RV-KNYVDWIMKTMQ 244 >2XXL-A nrPDB Length = 408 Score = 221 bits (563), Expect = 3e-58, Method: Composition-based stats. Identities = 72/267 (26%), Positives = 120/267 (44%), Gaps = 40/267 (14%) Query: 25 VCEKIIGGNEVTPHSRPYMVLLSLDR----KTICAGALIAKDWVLTAAHCNL---NKRSQ 77 + +++ G EV SRP+M LL + + +C GA+I++ ++LTAAHC N + Sbjct: 115 LSQRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDLYE 174 Query: 78 VILGAHSITREEPTKQI------------MLVKKEFPYPCYDPATREGDLKLLQLMEKAK 125 + LG H I+ EE +Q + ++K + YD D+ LL+L Sbjct: 175 IRLGEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNRSVP 234 Query: 126 INKYVTILHLPKKGDD---VKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDR 182 K++ + LP + + + V GWG T N S SD L + N+ + R C+ Sbjct: 235 FQKHIKPICLPITDELKEKAEQISTYFVTGWGTTEN-GSSSDVLLQANVPLQPRSACSQA 293 Query: 183 NHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFR----------GVTSFGLEN 232 + + ++ +C G +DSC GDSG PL + G+ S G+ Sbjct: 294 ----YRRAVPLSQLCVGGGDL-QDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVVT 348 Query: 233 KCGDPRGPGVYILLSKKHLNWIIMTIK 259 CG PG+Y + + ++ WI T+ Sbjct: 349 -CGQISLPGLYTNVGE-YVQWITDTMA 373 >1EQ9-A nrPDB Length = 222 Score = 219 bits (559), Expect = 8e-58, Method: Composition-based stats. Identities = 61/235 (25%), Positives = 102/235 (43%), Gaps = 18/235 (7%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLN----KRSQVILGAHS 84 I+GG + PY V L L C +++ + VLTAAHC R +V +G + Sbjct: 1 IVGGKDAPVGKYPYQVSLRLSGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVGTNY 60 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKP 144 ++ + + V+ YD D+ L+ L K N V + L +D++ Sbjct: 61 LS---ESGDVYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTNDEDLES 117 Query: 145 GTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 204 C + GWG T + + L+E+ + + +K C + + +C + G Sbjct: 118 N-PCTLTGWGSTRLGGNTPNALQEIELIVHPQKQCERDQWR-----VIDSHICT-LTKRG 170 Query: 205 RDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 +C+GDSG PL+ G G+ SFG + C P VY +S ++WI +K Sbjct: 171 EGACHGDSGGPLVANGAQIGIVSFG--SPCALGE-PDVYTRVS-SFVSWINANLK 221 >5XRF-A nrPDB Length = 242 Score = 219 bits (559), Expect = 9e-58, Method: Composition-based stats. Identities = 76/241 (31%), Positives = 117/241 (48%), Gaps = 12/241 (4%) Query: 24 DVCEKIIGGNEVTPHSRPYMVLLSLDRKTI--CAGALIAKDWVLTAAHCNLNKRSQVILG 81 E +IGGNE + ++ R CAG LI ++WVL AAHC + + LG Sbjct: 2 KSSELVIGGNECDTNEHRFLAAFFTSRPWTFQCAGTLIHEEWVLAAAHC-YKRGLNIYLG 60 Query: 82 AHSITREEPTKQIMLVKKEFPYPCYDPATR-EGDLKLLQLMEKAKINKYVTILHLPKKGD 140 H+ + + +Q +E Y C + T+ E D+ LL+L + + ++ L Sbjct: 61 MHNQSIQFDDEQRRYAIEEHYYRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPLS--LPSS 118 Query: 141 DVKPGTMCQVAGWGRTHNSAS-WSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAG 199 G++C+V GWG ++ D NI +++ C HY P ++CAG Sbjct: 119 PPSIGSVCRVMGWGIMSSTKDILPDVPHCANINLLNYMEC--VAHYPDVPE-TTRLLCAG 175 Query: 200 SLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 L GG D+CN DSG PL+C+G F+G+ FG + C P PG+Y +S + +WI I Sbjct: 176 VLEGGIDTCNQDSGGPLICDGQFQGIVFFG-KYPCAQPNKPGLYTRVS-NYNDWIQNIIA 233 Query: 260 G 260 G Sbjct: 234 G 234 >4BXW-A nrPDB Length = 423 Score = 219 bits (559), Expect = 9e-58, Method: Composition-based stats. Identities = 63/255 (24%), Positives = 105/255 (41%), Gaps = 26/255 (10%) Query: 23 EDVCEKIIGGNEVTPHSRPYMVLLSLDRKT-ICAGALIAKDWVLTAAHC-NLNKRSQVIL 80 +I+ G + P+ L +++ C G +++ +VLTAAHC N + V++ Sbjct: 164 PSPDIRIVNGMDCKLGECPWQAALVDEKEGVFCGGTILSPIYVLTAAHCINETETISVVV 223 Query: 81 GAHSITREEPTKQIMLVKKEFPYPCYDP---------ATREGDLKLLQLMEKAKINKYVT 131 G +R E T ++ V K + + + P A + D+ ++Q+ + ++ V Sbjct: 224 GEIDKSRIE-TGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQFSENVV 282 Query: 132 ILHLPK---KGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFN 188 LP + V+G+GR S TL+ + + +DR C + Sbjct: 283 PACLPTADFANQVLMKQDFGIVSGFGRIVEKGPKSKTLKVLKVPYVDRHTCMVSSETP-- 340 Query: 189 PVIGMNMVCAGSLRGGRDSCNGDSGSPL--LCEGV--FRGVTSFGLENKCGDPRGPGVYI 244 I NM CAG RD+C GDSG P + G+ S G C G Y Sbjct: 341 --ITPNMFCAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSG--EGCARNGKYGNYT 396 Query: 245 LLSKKHLNWIIMTIK 259 LS K + WI ++ Sbjct: 397 KLS-KFIPWIKRIMR 410 >5KWM-A nrPDB Length = 230 Score = 218 bits (555), Expect = 2e-57, Method: Composition-based stats. Identities = 69/239 (28%), Positives = 102/239 (42%), Gaps = 17/239 (7%) Query: 29 IIGGNEVTPHSRPYMVLL-SLDRKTICAGALIAKDWVLTAAHCNLNKRS---QVILGAHS 84 I+GG + P+ V L + D + C G L A + V+TAAHC + + V+ G Sbjct: 1 IVGGEDANVQDHPFTVALVTPDGQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSGRTV 60 Query: 85 ITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDD-VK 143 ++ E T + V + +P Y A + D+ +L L K + L K D Sbjct: 61 MSSNEGT--VSKVTNVWVHPEYQDAAKGFDVSVLTLEAPVKE----APIELAKADDAGYA 114 Query: 144 PGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRG 203 P T + GWG T +D L++ + + C + MVCAG G Sbjct: 115 PDTAATILGWGNTSEGGQQADHLQKATVPVNSDDTCKQA----YGEYTPDAMVCAGVPEG 170 Query: 204 GRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKGAV 262 G D+C GDSG P++ GVTS+G C P PGVY + + + GAV Sbjct: 171 GVDTCQGDSGGPMVVNNKLIGVTSWG--EGCARPGKPGVYARVGAYYDVLMEQINAGAV 227 >2QY0-B nrPDB Length = 242 Score = 217 bits (554), Expect = 3e-57, Method: Composition-based stats. Identities = 66/249 (26%), Positives = 103/249 (41%), Gaps = 28/249 (11%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQ--------VIL 80 IIGG + + P+ V ++ + GAL+ W+LTAAH K + V L Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSNASLDVFL 58 Query: 81 GAHSITREEPTKQIMLVKKEFPYPCYDPA---TREGDLKLLQLMEKAKINKYVTILHLPK 137 G H+ E +++ +P Y EGD+ LL+L + + + LP Sbjct: 59 G-HTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICLPD 117 Query: 138 KGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVC-NDRNHYNFNPVIGMNMV 196 G M V+G+G + LR V + + + + C N N V NM Sbjct: 118 NDTFYDLGLMGYVSGFGVMEE--KIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQNMF 175 Query: 197 CAGSLRGGRDSCNGDSGS------PLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKH 250 CAG +D+C GDSG P V G+ S+G+ G RG G Y + + Sbjct: 176 CAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGI----GCSRGYGFYTKV-LNY 230 Query: 251 LNWIIMTIK 259 ++WI ++ Sbjct: 231 VDWIKKEME 239 >2XRC-A nrPDB Length = 565 Score = 217 bits (554), Expect = 3e-57, Method: Composition-based stats. Identities = 61/240 (25%), Positives = 99/240 (41%), Gaps = 22/240 (9%) Query: 28 KIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNL-NKRSQVILGAHSIT 86 +I+GG P+ V + C G I W+LTAAHC +K + + + Sbjct: 321 RIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 380 Query: 87 REEPTKQIM---LVKKEFPYPCYDPATREGDLKLLQLMEKAKINK----YVTILHLPKKG 139 P + + V + + Y+ T + D+ L+++ + +P Sbjct: 381 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 440 Query: 140 DDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAG 199 +P C V+GWGR ++ L+ + +I C+ + N M CAG Sbjct: 441 YLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISN--CSK---FYGNRFYEKEMECAG 494 Query: 200 SLRGGRDSCNGDSGSPLLCEG-----VFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 + G D+C GDSG PL+C GV S+G CG P PGVY ++ + +WI Sbjct: 495 TYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG--ENCGKPEFPGVYTKVA-NYFDWI 551 >2OLG-A nrPDB Length = 278 Score = 217 bits (553), Expect = 4e-57, Method: Composition-based stats. Identities = 67/276 (24%), Positives = 124/276 (44%), Gaps = 41/276 (14%) Query: 19 LLIPEDV-----CEKIIGGNEVTPHSRPYMVLLSLDR-----KTICAGALIAKDWVLTAA 68 L+P D +KI+ G++ P P+ ++ + C G+LI +++TAA Sbjct: 8 ELLPNDCGYQVEADKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAA 67 Query: 69 HCNLNKRSQVILGAHSITREE-----------------PTKQI-MLVKKEFPYPCYDPAT 110 HC + +V+ + + E P K I + +++ +P Y + Sbjct: 68 HCVAGRVLRVVGALNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVDGS 127 Query: 111 RE--GDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLRE 168 ++ D+ L++L + + Y+ + LP+ ++V+ G V GWGRT + +S ++ Sbjct: 128 KDRYHDIALIRLNRQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRT-ETGQYSTIKQK 186 Query: 169 VNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGV-----FR 223 + + ++ + C + + + +CAG +DSC GDSG PLL E Sbjct: 187 LAVPVVHAEQC-AKTFGAAGVRVRSSQLCAGG-EKAKDSCGGDSGGPLLAERANQQFFLE 244 Query: 224 GVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 G+ SFG CG PG+Y + K+ +WI I+ Sbjct: 245 GLVSFGAT--CGTEGWPGIYTKVG-KYRDWIEGNIR 277 >1YM0-A nrPDB Length = 238 Score = 216 bits (551), Expect = 8e-57, Method: Composition-based stats. Identities = 68/243 (27%), Positives = 101/243 (41%), Gaps = 21/243 (8%) Query: 29 IIGGNEVTPHSRPYMVLLS--LDRKTICAGALIAKDWVLTAAHCNLNKRS---QVILGAH 83 I+GG E P+ P+ V + C G++I WV+ AAHC + +++G H Sbjct: 1 IVGGIEARPYEFPWQVSVRRKSSDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVGEH 60 Query: 84 SITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVK 143 + +Q V F YDPAT E D+ +++ + V + P +D Sbjct: 61 DSSAASTVRQTHDVDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICAPDPANDYV 120 Query: 144 PGTMCQVAGWGRTHNSA-SWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR 202 Q +GWG ++ LR V + I C+ + I +M+CA Sbjct: 121 Y-RKSQCSGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVY---TSDTIYDDMICATDNT 176 Query: 203 G--GRDSCNGDSGSPLLCEG-----VFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWII 255 G RDSC GDSG PL + G+ S+G+ C PGVY + H WI Sbjct: 177 GMTDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWGI--GCAS-GYPGVYSRVG-FHAGWIT 232 Query: 256 MTI 258 TI Sbjct: 233 DTI 235 >4WJG-C nrPDB Length = 315 Score = 214 bits (546), Expect = 3e-56, Method: Composition-based stats. Identities = 62/279 (22%), Positives = 117/279 (41%), Gaps = 35/279 (12%) Query: 6 RFLASSLSVVVSLLLIPEDV---CEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKD 62 + + L ++ P++ ++I+GG+ S P+ + LI + Sbjct: 45 KAVGDKLPECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQ 104 Query: 63 WVLTAA---HCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQ 119 W+LT A N ++ + A ++T KQ++ ++K +P Y D+ L++ Sbjct: 105 WLLTTAKNLFLNHSENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQV----DIGLIK 160 Query: 120 LMEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVC 179 L +K +N+ V + LP K + G + V+GWGR N ++D L+ V + + D+ C Sbjct: 161 LKQKVSVNERVMPICLPSKDY-AEVGRVGYVSGWGRNAN-FKFTDHLKYVMLPVADQDQC 218 Query: 180 -------------NDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCE------G 220 ++ P++ + CAG + D+C GD+GS Sbjct: 219 IRHYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTW 278 Query: 221 VFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 G+ SF + C GVY+ ++ +W+ TI Sbjct: 279 YATGILSF--DKSCAVAE-YGVYVKVTSIQ-DWVQKTIA 313 >6BQM-A nrPDB Length = 506 Score = 214 bits (545), Expect = 3e-56, Method: Composition-based stats. Identities = 68/248 (27%), Positives = 108/248 (43%), Gaps = 22/248 (8%) Query: 25 VCEKIIGGNEVTPHSRPYMVLLSLDRKT--ICAGALIAKDWVLTAAHCNLNKRS---QVI 79 V +IIGG + T PYMV L+ + C G+ + +VLTAAHC + V+ Sbjct: 7 VSSRIIGGEQATAGEWPYMVALTARNSSHVFCGGSYLGGRYVLTAAHCVDKEDPAKGDVL 66 Query: 80 LGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKG 139 LGA + ++I V++ + + Y A+ D+ +L+L + V I Sbjct: 67 LGAFDMNDVNTAERIH-VRQIYVHNSYITASMGNDIAVLELERDPLPRRSVQISDSSDFN 125 Query: 140 DDVKPGTMCQVAGWGRTHNSASWSD---TLREVNITIIDRKVC----NDRNHYNFNPVIG 192 + K M + R SD L +V + + C +D++ N + Sbjct: 126 ELTKDSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGSDQDAKNNYSQLT 185 Query: 193 MNMVCAGSLRGGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSK 248 N CAGS G+D+C+GD+G P+ + GV S+G + CG PGVY LS Sbjct: 186 NNAFCAGSF--GKDACSGDAGGPIFFDSNNGRKQMGVVSWG--DGCGRANSPGVYTNLSV 241 Query: 249 KHLNWIIM 256 +W+ Sbjct: 242 -FNDWLDD 248 >5O32-I nrPDB Length = 244 Score = 213 bits (544), Expect = 4e-56, Method: Composition-based stats. Identities = 61/239 (25%), Positives = 98/239 (41%), Gaps = 22/239 (9%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNL-NKRSQVILGAHSITR 87 I+GG P+ V + C G I W+LTAAHC +K + + + Sbjct: 1 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 60 Query: 88 EEPTKQIM---LVKKEFPYPCYDPATREGDLKLLQLMEKAKINK----YVTILHLPKKGD 140 P + + V + + Y+ T + D+ L+++ + +P Sbjct: 61 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 120 Query: 141 DVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGS 200 +P C V+GWGR ++ L+ + +I C+ + N M CAG+ Sbjct: 121 LFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISN--CSK---FYGNRFYEKEMECAGT 174 Query: 201 LRGGRDSCNGDSGSPLLCEG-----VFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWI 254 G D+C GDSG PL+C GV S+G CG P PGVY ++ + +WI Sbjct: 175 YDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG--ENCGKPEFPGVYTKVA-NYFDWI 230 >4LK4-A nrPDB Length = 357 Score = 213 bits (543), Expect = 7e-56, Method: Composition-based stats. Identities = 60/246 (24%), Positives = 108/246 (43%), Gaps = 19/246 (7%) Query: 23 EDVCEKIIGGNEVTPHSRPYMVLLSLDR-----KTICAGALIAKDWVLTAAHCNLNK--- 74 D+ +II G+ P +V L C G+ + +VLTAAHC ++ Sbjct: 5 ADISSRIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRSAA 64 Query: 75 RSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILH 134 VI+GA+ + ++I +K + + Y P+ D+ +++L + + + L Sbjct: 65 SVDVIIGAYDLNNSSQGERI-AAQKIYRHLSYSPSNLLNDIAIVELAQTSSL--PAITLA 121 Query: 135 LPKKGDDVKPGTMCQVAGWGRTHNSAS--WSDTLREVNITIIDRKVCNDRNHYNFNPVIG 192 P + T VAGWG T S ++ L+EV++ ++ + +C + + Sbjct: 122 GPATRTSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQHGISSDPN 181 Query: 193 MNMVCAGSLRGGRDSCNGDSGSPLLCE--GVFRGVTSFGLENKCGDPRGPGVYILLSKKH 250 CA L +DSC GD+G P++ + G+ S+G + +C GVY +S Sbjct: 182 STNFCAARLT--KDSCQGDAGGPIVVKTGREQLGIVSWG-DEQCAKTGTYGVYTNVS-YF 237 Query: 251 LNWIIM 256 +WI Sbjct: 238 RDWITK 243 >4F4O-C nrPDB Length = 347 Score = 212 bits (539), Expect = 2e-55, Method: Composition-based stats. Identities = 63/286 (22%), Positives = 116/286 (40%), Gaps = 49/286 (17%) Query: 6 RFLASSLSVVVSLLLIPE---DVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKD 62 + L ++ P+ D ++I+GG+ S P+ + LI + Sbjct: 77 KVTGEKLPECEAVCGKPKNPVDQVQRIMGGSLDAKGSFPWQAKMISHHNLTSGATLINEQ 136 Query: 63 WVLTAAHCNLNKRSQVILGAHSITREE----------PTKQIMLVKKEFPYPCYDPATRE 112 W+LT A + LG + T+ + KQ + ++K +P Sbjct: 137 WLLTTA-------KNLRLGHKNDTKAKDIAPTLRLYVGKKQEVEIEKVIFHP----DNST 185 Query: 113 GDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNIT 172 D+ L++L +K +N+ V + LP K V G + V+GWGR N ++++ L+ V + Sbjct: 186 VDIGLIKLKQKVPVNERVMPICLPSKDY-VNVGLVGYVSGWGRNAN-LNFTEHLKYVMLP 243 Query: 173 IIDRKVC-------------NDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCE 219 + D++ C ++ P++ + CAG + D+C GD+GS Sbjct: 244 VADQEKCVQYYEGSTVPEKKTPKSPVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFAVH 303 Query: 220 ------GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 G+ SF + + GVY+ ++ L+WI TI Sbjct: 304 DKDDDTWYAAGILSFDKSCRTAE---YGVYVRVTSI-LDWIQTTIA 345 >2B9L-A nrPDB Length = 394 Score = 210 bits (535), Expect = 5e-55, Method: Composition-based stats. Identities = 66/255 (25%), Positives = 110/255 (43%), Gaps = 32/255 (12%) Query: 33 NEVTPHSRPYMVLL--------SLDRKTICAGALIAKDWVLTAAHCNLNKRSQ-----VI 79 NE P+MV + S + + +C G+LIA VLT AHC + +S + Sbjct: 135 NEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHCVNSYQSNLDAIKIR 194 Query: 80 LGAHSITREEP--TKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPK 137 G E+ Q +++ + ++P T D+ LL L + + LP+ Sbjct: 195 AGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLLDRPLVQADNIGTICLPQ 254 Query: 138 KGDDVKPGTMCQVAGWGRTHNSA--SWSDTLREVNITIIDRKVCN---DRNHYNFNPVIG 192 + T C +GWG+ + +S+ L+++ + +DR C V+ Sbjct: 255 QSQIF-DSTECFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQADLRNTRLGLKFVLD 313 Query: 193 MNMVCAGSLRGGRDSCNGDSGSPLLCEG-------VFRGVTSFGLENKCGDPRGPGVYIL 245 VCAG + G+D+C GD GSPL C + G+ ++G+ CGD PGVY Sbjct: 314 QTFVCAGGEQ-GKDTCTGDGGSPLFCPDPRNPSRYMQMGIVAWGI--GCGDENVPGVYAN 370 Query: 246 LSKKHLNWIIMTIKG 260 ++ NWI ++ Sbjct: 371 VA-HFRNWIDQEMQA 384 >4X0L-C nrPDB Length = 259 Score = 209 bits (532), Expect = 1e-54, Method: Composition-based stats. Identities = 61/260 (23%), Positives = 111/260 (42%), Gaps = 32/260 (12%) Query: 22 PEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAA---HCNLNKRSQV 78 P + ++I+GG+ S P+ + LI + W+LT A N ++ + Sbjct: 8 PANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATA 67 Query: 79 ILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKK 138 A ++T KQ++ ++K +P Y D+ L++L +K +N+ V + LP K Sbjct: 68 KDIAPTLTLYVGKKQLVEIEKVVLHPNYSQV----DIGLIKLKQKVSVNERVMPICLPSK 123 Query: 139 GDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVC-------------NDRNHY 185 + G + V+GWGR N ++D L+ V + + D+ C ++ Sbjct: 124 DY-AEVGRVGYVSGWGRNAN-FKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPV 181 Query: 186 NFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCE------GVFRGVTSFGLENKCGDPRG 239 P++ + CAG + D+C GD+GS G+ SF + C Sbjct: 182 GVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSF--DKSCAVAE- 238 Query: 240 PGVYILLSKKHLNWIIMTIK 259 GVY+ ++ +W+ TI Sbjct: 239 YGVYVKVTSIQ-DWVQKTIA 257 >3I77-A nrPDB Length = 230 Score = 208 bits (530), Expect = 2e-54, Method: Composition-based stats. Identities = 63/228 (27%), Positives = 97/228 (42%), Gaps = 20/228 (8%) Query: 29 IIGGNEVTPHSRPYMV-LLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITR 87 ++GG P+MV L++ + + C GAL A+D VLTAAHC + + A Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEGFCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVV 60 Query: 88 EEPTKQIMLVK--KEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 + + + V+ K P + T D L++L + N+ + G Sbjct: 61 DLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPI--NQPTLKIATTTA---YNQG 115 Query: 146 TMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLR-GG 204 T VAGWG S L + N+ + C + + ++ M+CAG GG Sbjct: 116 TF-TVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSF---ILVANEMICAGYPDTGG 171 Query: 205 RDSCNGDSGSPLL-----CEGVFRGVTSFGLENKCGDPRGPGVYILLS 247 D+C GDSG P+ E + G+ S+G C P PGVY +S Sbjct: 172 VDTCQGDSGGPMFRKDNADEWIQVGIVSWGY--GCARPGYPGVYTEVS 217 >1PQ7-A nrPDB Length = 224 Score = 207 bits (528), Expect = 3e-54, Method: Composition-based stats. Identities = 68/225 (30%), Positives = 96/225 (42%), Gaps = 15/225 (6%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLN---KRSQVILGAHSI 85 I+GG + P++V +S + C G+L+ + VLTAAHC Q+ G+ S Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQIRAGSLSR 60 Query: 86 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPG 145 T T + V+ +P Y + DL +L+L + L G D G Sbjct: 61 TSGGITSSLSSVR---VHPSY--SGNNNDLAILKLSTSIPSGGNIGYARLAASGSDPVAG 115 Query: 146 TMCQVAGWGRTHNSA-SWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 204 + VAGWG T S L +V + I+ R C + I M CAG GG Sbjct: 116 SSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQY---GTSAITNQMFCAGVSSGG 172 Query: 205 RDSCNGDSGSPLLC-EGVFRGVTSFGLENKCGDPRGPGVYILLSK 248 +DSC GDSG P++ G S+G N C P GVY + Sbjct: 173 KDSCQGDSGGPIVDSSNTLIGAVSWG--NGCARPNYSGVYASVGA 215 >3BEU-A nrPDB Length = 224 Score = 203 bits (518), Expect = 4e-53, Method: Composition-based stats. Identities = 61/226 (26%), Positives = 91/226 (40%), Gaps = 22/226 (9%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 ++GG P+MV LS+ C GAL A+D VLTAAHC + + A + Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG----CGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 89 EPTKQIMLVK--KEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGT 146 + + V+ K P + T D L++L + N+ + GT Sbjct: 57 LQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPI--NQPTLKIATTTA---YNQGT 111 Query: 147 MCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRD 206 VAGWG S L + N+ + C + + ++ M+CAG D Sbjct: 112 FT-VAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSF---ILVANEMICAGYDTKQED 167 Query: 207 SCNGDSGSPLL-----CEGVFRGVTSFGLENKCGDPRGPGVYILLS 247 +C GDSG P+ E V G+ S+G C GVY +S Sbjct: 168 TCQGDSGGPMFRKDNADEWVQVGIVSWG--EGCARKGKYGVYTEVS 211 >2ASU-B nrPDB Length = 234 Score = 198 bits (503), Expect = 2e-51, Method: Composition-based stats. Identities = 63/243 (25%), Positives = 106/243 (43%), Gaps = 29/243 (11%) Query: 29 IIGGNEVTPHSRPYMVLL-SLDRKTICAGALIAKDWVLTAAHCNLN-----KRSQVILGA 82 ++GG+ P + P+ V L + + C G+L+ + W+LTA C + +V LG Sbjct: 1 VVGGH---PGNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWLGT 57 Query: 83 --HSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGD 140 + EP+ Q + V K P L LL+L +N+ V ++ LP + Sbjct: 58 LFQNPQHGEPSLQRVPVAKMVCGPS------GSQLVLLKLERSVTLNQRVALICLPPEWY 111 Query: 141 DVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGS 200 V PGT C++AGWG T + + + L + +I + CN ++ + + +C Sbjct: 112 VVPPGTKCEIAGWGETKGTGNDT-VLNVALLNVISNQECNIKH----RGRVRESEMCTEG 166 Query: 201 LRGGRDSCNGDSGSPLLC----EGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIM 256 L +C GD G PL C V G+ C R P V+ +S ++WI Sbjct: 167 LLAPVGACEGDYGGPLACFTHNSWVLEGIII--PNRVCARSRWPAVFTRVSV-FVDWIHK 223 Query: 257 TIK 259 ++ Sbjct: 224 VMR 226 >2FMJ-A nrPDB Length = 222 Score = 196 bits (499), Expect = 7e-51, Method: Composition-based stats. Identities = 62/226 (27%), Positives = 91/226 (40%), Gaps = 24/226 (10%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 ++GG P+MV LS+ C GAL A+D VLTAAHC + + A + Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG----CGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 89 EPTKQIMLVK--KEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGT 146 + + V+ K P Y+ D L++L + N+ + GT Sbjct: 57 LQSSSAVKVRSTKVLQAPGYN--GTGKDWALIKLAQPI--NQPTLKIATTTA---YNQGT 109 Query: 147 MCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRD 206 VAGWG S L + N+ + C N ++ +CAG GG D Sbjct: 110 FT-VAGWGANREGGSQQRYLLKANVPFVSDAACRSAY---GNELVANEEICAGYDTGGVD 165 Query: 207 SCNGDSGSPLL-----CEGVFRGVTSFGLENKCGDPRGPGVYILLS 247 +C GDSG P+ E + G+ S+G C GVY +S Sbjct: 166 TCQGDSGGPMFRKDNADEWIQVGIVSWG--EGCARKGKYGVYTEVS 209 >2HLC-A nrPDB Length = 230 Score = 196 bits (498), Expect = 1e-50, Method: Composition-based stats. Identities = 55/238 (23%), Positives = 98/238 (41%), Gaps = 22/238 (9%) Query: 29 IIGGNEVTPHSRPYMV----LLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVI-LGAH 83 II G E PY L R+ C G+LI W+LTAAHC + S V+ LG+ Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHDAVSVVVYLGS- 59 Query: 84 SITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVK 143 + + ++ ++ + ++P T D+ L+++ + + + LP + Sbjct: 60 --AVQYEGEAVVNSERIISHSMFNPDTYLNDVALIKI-PHVEYTDNIQPIRLPSGEELNN 116 Query: 144 --PGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSL 201 V+GWG+++ + L+ +ID C + P I + G Sbjct: 117 KFENIWATVSGWGQSNTD---TVILQYTYNLVIDNDRC----AQEYPPGIIVESTICGDT 169 Query: 202 RGGRDSCNGDSGSPLLC--EGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMT 257 G+ C GDSG P + + + GV SF C + P + ++ +++WI Sbjct: 170 SDGKSPCFGDSGGPFVLSDKNLLIGVVSFVSGAGC-ESGKPVGFSRVT-SYMDWIQQN 225 >1SI5-H nrPDB Length = 240 Score = 194 bits (493), Expect = 4e-50, Method: Composition-based stats. Identities = 68/241 (28%), Positives = 109/241 (45%), Gaps = 26/241 (10%) Query: 29 IIGG--NEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLN---KRSQVILGAH 83 ++ G +MV L K IC G+LI + WVLTA C + K + LG H Sbjct: 1 VVNGIPTRTNIG---WMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIH 57 Query: 84 SI--TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDD 141 + +E KQ++ V + P DL L++L A ++ +V+ + LP G Sbjct: 58 DVHGRGDEKCKQVLNVSQLVYGPE------GSDLVLMKLARPAVLDDFVSTIDLPNYGST 111 Query: 142 VKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSL 201 + T C V GWG T ++ LR ++ I+ + C+ H+ + + +CAG+ Sbjct: 112 IPEKTSCSVYGWGYTG-LINYDGLLRVAHLYIMGNEKCSQ--HHRGKVTLNESEICAGAE 168 Query: 202 RGGRDSCNGDSGSPLLCE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMT 257 + G C GD G PL+CE + GV G C P PG+++ ++ + WI Sbjct: 169 KIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPG--RGCAIPNRPGIFVRVA-YYAKWIHKI 225 Query: 258 I 258 I Sbjct: 226 I 226 >3H7T-A nrPDB Length = 235 Score = 191 bits (485), Expect = 3e-49, Method: Composition-based stats. Identities = 63/237 (26%), Positives = 103/237 (43%), Gaps = 8/237 (3%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 IIGG + P+ V + +D K C G+++ ++V+TAA C + I H + Sbjct: 1 IIGGKKSDITKEPWAVGVLVDEKPFCGGSILTANFVITAAQCVDGTKPSDI-SIHYGSSY 59 Query: 89 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINK-YVTILHLPKKGDDVKPGTM 147 TK ++ K+ Y P T + + +++ K++ + LP D +P T Sbjct: 60 RTTKGTSVMAKKIYIVRYHPLTMQNNYAVIETEMPIKLDDKTTKKIELPSLLYDPEPDTS 119 Query: 148 CQVAGWGRTH-NSASWSDTLREVNITIIDRKVCNDRN-HYNFNPVIGMNMVCAGSLRGGR 205 V+GWG T+ S +S L E N T++DRK C ++ + I + CAG Sbjct: 120 VLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGVFCAGGEYDET 179 Query: 206 DSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKGAV 262 GD+G P + G GV S+ P V++ + L+ I I G V Sbjct: 180 YIGYGDAGDPAVQNGTLVGVASYISSMP---SEFPSVFLRVGYYVLD-IKDIISGKV 232 >5XW8-A nrPDB Length = 133 Score = 188 bits (477), Expect = 2e-48, Method: Composition-based stats. Identities = 48/137 (35%), Positives = 70/137 (51%), Gaps = 4/137 (2%) Query: 21 IPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVIL 80 P D +KI+GG +S PY V L+ C G+LI WV++AAHC R QV L Sbjct: 1 FPTDDDDKIVGGYTCAANSIPYQVSLNS-GSHFCGGSLINSQWVVSAAHC-YKSRIQVRL 58 Query: 81 GAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGD 140 G H+I E +Q + K +P ++ T + D+ L++L A +N V + LP+ Sbjct: 59 GEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSC- 117 Query: 141 DVKPGTMCQVAGWGRTH 157 GT C ++GWG T Sbjct: 118 -AAAGTECLISGWGNTK 133 >1M9U-A nrPDB Length = 241 Score = 183 bits (465), Expect = 7e-47, Method: Composition-based stats. Identities = 63/242 (26%), Positives = 96/242 (39%), Gaps = 15/242 (6%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRK---TICAGALIAKDWVLTAAHCN---LNKRSQVILGA 82 +IGG +P P+ + C +L++ L+A+HC L +VI G Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAGL 60 Query: 83 HSITREEPTKQIMLVKKEFPYPCYDPAT--REGDLKLLQLMEKAKINKYVTILHLPKKGD 140 + Q V + Y T D+ +L L + + LP + Sbjct: 61 -WQQSDTSGTQTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANNN 119 Query: 141 DVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGS 200 + GT C ++GWGRT + + D L++ +I +I C I N +C Sbjct: 120 NDYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVGGANIWDNHICVQD 179 Query: 201 LRGGRDSCNGDSGSPLLCEG---VFRGVTSFGLENKCGD--PRGPGVYILLSKKHLNWII 255 G +CNGDSG PL C GVTS+ + + G P P VY +S +L WI Sbjct: 180 PAGNTGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGACLPDYPSVYTRVSA-YLGWIG 238 Query: 256 MT 257 Sbjct: 239 DN 240 >3H7O-A nrPDB Length = 228 Score = 183 bits (465), Expect = 7e-47, Method: Composition-based stats. Identities = 54/235 (22%), Positives = 99/235 (42%), Gaps = 16/235 (6%) Query: 31 GGNEVTPHSRPYMVLLSL---DRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSIT- 86 GG + P+ V + + C GA++++ +VLTAAHC +++ + I+ + T Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTN 61 Query: 87 -REEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKI-NKYVTILHLPKKGDDVKP 144 E+P K V + Y T E D+ +L+L K+ LP K Sbjct: 62 LWEDPGKSDPYVSHVYL-SFYRQETMENDIAILELSRPLKLDGLKSKPAKLPDIEFRPKT 120 Query: 145 GTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 204 G+ V+G+G L+ +T++D C + + + + CA + G Sbjct: 121 GSDVLVSGYGDGQTMDPKDHDLKSAQLTVVDLDECRTKY---GPIFLSLQVFCAQKV--G 175 Query: 205 RDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 259 +GD+G P + + GV ++ + G P V+ + +++WI IK Sbjct: 176 VSLESGDAGDPTVQQDTLVGVAAYFPKRPEG---APEVFTKVG-SYVSWIQDIIK 226 >2PKA-B nrPDB Length = 152 Score = 175 bits (445), Expect = 1e-44, Method: Composition-based stats. Identities = 54/155 (34%), Positives = 83/155 (53%), Gaps = 11/155 (7%) Query: 107 DPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNS---ASWS 163 D DL LL+L AKI V +L LP + ++ G+ C+ +GWG + Sbjct: 2 DGKDYSHDLMLLRLQSPAKITDAVKVLELPTQEPEL--GSTCEASGWGSIEPGPDDFEFP 59 Query: 164 DTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFR 223 D ++ V +T++ C D + + +M+CAG L GG+D+C GDSG PL+C G+++ Sbjct: 60 DEIQCVQLTLLQNTFCADAH----PDKVTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQ 115 Query: 224 GVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 G+TS+G CG P +Y L +L+WI TI Sbjct: 116 GITSWGH-TPCGSANKPSIYTKL-IFYLDWIDDTI 148 >3VGC-B nrPDB Length = 131 Score = 171 bits (433), Expect = 4e-43, Method: Composition-based stats. Identities = 43/130 (33%), Positives = 60/130 (46%), Gaps = 1/130 (0%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRK-TICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITR 87 I+ G E P S P+ V L C G+LI ++WV+TAAHC + V+ G Sbjct: 1 IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQGS 60 Query: 88 EEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTM 147 Q + + K F Y+ T D+ LL+L A ++ V+ + LP DD GT Sbjct: 61 SSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAAGTT 120 Query: 148 CQVAGWGRTH 157 C GWG T Sbjct: 121 CVTTGWGLTR 130 >2JET-B nrPDB Length = 128 Score = 168 bits (425), Expect = 3e-42, Method: Composition-based stats. Identities = 43/127 (33%), Positives = 67/127 (52%), Gaps = 1/127 (0%) Query: 32 GNEVTPHSRPYMVLLSLDRK-TICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITREEP 90 G + P S P+ V L C G+LI++DWV+TAAHC + V+ G +E Sbjct: 1 GEDAIPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHCGVKTSDVVVAGEFDQGSDEE 60 Query: 91 TKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMCQV 150 Q++ + + F P ++ T D+ LL+L A+ ++ V+ + LP DD PGT+C Sbjct: 61 NIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDFPPGTVCAT 120 Query: 151 AGWGRTH 157 GWG+T Sbjct: 121 TGWGKTK 127 >2I6S-A nrPDB Length = 517 Score = 161 bits (407), Expect = 4e-40, Method: Composition-based stats. Identities = 51/228 (22%), Positives = 90/228 (39%), Gaps = 35/228 (15%) Query: 41 PYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKE 100 P+ V + + C GALI+ WVLTAAHC + + + + + L++K Sbjct: 244 PWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEFLIEKA 303 Query: 101 FPYPCYDPATREG---------DLKLLQLMEKAKINKYVTILHLPKKGD-----DVKPGT 146 P +D ++ D+ LL+L +K K++ + + LP + G+ Sbjct: 304 VISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQGS 363 Query: 147 MCQ-----------VAGWGRTHNSASWSDTLRE-VNITIIDRKVCNDRNHY----NFNPV 190 C+ V N + + L+ V T V ++ + + V Sbjct: 364 TCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPNLTDVREV 423 Query: 191 IGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFR----GVTSFGLENKC 234 + +C+G+ C G+SG + E FR G+ S+GL N C Sbjct: 424 VTDQFLCSGTQED-ESPCKGESGGAVFLERRFRFFQVGLVSWGLYNPC 470 >1RIW-B nrPDB Length = 147 Score = 157 bits (397), Expect = 5e-39, Method: Composition-based stats. Identities = 39/147 (26%), Positives = 71/147 (48%), Gaps = 16/147 (10%) Query: 29 IIGGNEVTPHSRPYMVLLSLD--RKTICAGALIAKDWVLTAAHCNLNKRSQ--------- 77 I+ G++ P+ V+L ++ +C +LI+ WVLTAAHC L Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 78 VILGAHSITREEPT-KQIMLVKKEFPYPCYD-PATREGDLKLLQLMEKAKINKYVTILHL 135 V +G HS TR E ++I +++K + +P Y+ + D+ L++L + + Y+ + L Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL 120 Query: 136 PKK---GDDVKPGTMCQVAGWGRTHNS 159 P + ++ G +V GWG + Sbjct: 121 PDRETAASLLQAGYKGRVTGWGNLKET 147 >2WIN-I nrPDB Length = 507 Score = 156 bits (395), Expect = 8e-39, Method: Composition-based stats. Identities = 56/252 (22%), Positives = 97/252 (38%), Gaps = 56/252 (22%) Query: 35 VTPHSRPYMVLLSL----DRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITREEP 90 H +P+ +S+ C GA++++ +VLTAAHC V HSI Sbjct: 229 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF-----TVDDKEHSIKVSVG 283 Query: 91 TKQI-MLVKKEFPYPCYD---------PATREGDLKLLQLMEKAKINKYVTILHLP---- 136 ++ + ++ +P Y+ P + D+ L++L K K + + + LP Sbjct: 284 GEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEG 343 Query: 137 -KKGDDVKPGTMCQVAGWGRTHNSASWSD-------------TLREVNITIIDRK-VCND 181 + + P T CQ + D T +EV I D+K C Sbjct: 344 TTRALRLPPTTTCQQ----QKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCER 399 Query: 182 RNHY--------NFNPVIGMNMVCAGSLRGGRD--SCNGDSGSPLLCEG----VFRGVTS 227 Y + + V+ +C G + D +C GDSG PL+ + GV S Sbjct: 400 DAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVIS 459 Query: 228 FGLENKCGDPRG 239 +G+ + C + + Sbjct: 460 WGVVDVCKNQKR 471 >1DLE-A nrPDB Length = 298 Score = 154 bits (389), Expect = 5e-38, Method: Composition-based stats. Identities = 56/252 (22%), Positives = 97/252 (38%), Gaps = 56/252 (22%) Query: 35 VTPHSRPYMVLLSL----DRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITREEP 90 H +P+ +S+ C GA++++ +VLTAAHC V HSI Sbjct: 22 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF-----TVDDKEHSIKVSVG 76 Query: 91 TKQI-MLVKKEFPYPCYD---------PATREGDLKLLQLMEKAKINKYVTILHLP---- 136 ++ + ++ +P Y+ P + D+ L++L K K + + + LP Sbjct: 77 GEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEG 136 Query: 137 -KKGDDVKPGTMCQVAGWGRTHNSASWSD-------------TLREVNITIIDRK-VCND 181 + + P T CQ + D T +EV I D+K C Sbjct: 137 TTRALRLPPTTTCQQ----QKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCER 192 Query: 182 RNHY--------NFNPVIGMNMVCAGSLRGGRD--SCNGDSGSPLLCEG----VFRGVTS 227 Y + + V+ +C G + D +C GDSG PL+ + GV S Sbjct: 193 DAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVIS 252 Query: 228 FGLENKCGDPRG 239 +G+ + C + + Sbjct: 253 WGVVDVCKNQKR 264 >1BBR-H nrPDB Length = 150 Score = 153 bits (386), Expect = 8e-38, Method: Composition-based stats. Identities = 42/150 (28%), Positives = 70/150 (46%), Gaps = 16/150 (10%) Query: 29 IIGGNEVTPHSRPYMVLLSLD--RKTICAGALIAKDWVLTAAHCNLNKRSQ--------- 77 I+ G + P+ V+L ++ +C +LI+ WVLTAAHC L Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 78 VILGAHSITREEPT-KQIMLVKKEFPYPCYD-PATREGDLKLLQLMEKAKINKYVTILHL 135 V +G HS TR E ++I ++ K + +P Y+ + D+ LL+L +++ Y+ + L Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCL 120 Query: 136 PKKGDDVK---PGTMCQVAGWGRTHNSASW 162 P K K G +V GWG + + Sbjct: 121 PDKQTAAKLLHAGFKGRVTGWGNRRETWTT 150 >2OK5-A nrPDB Length = 752 Score = 152 bits (385), Expect = 1e-37, Method: Composition-based stats. Identities = 56/252 (22%), Positives = 97/252 (38%), Gaps = 56/252 (22%) Query: 35 VTPHSRPYMVLLSL----DRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITREEP 90 H +P+ +S+ C GA++++ +VLTAAHC V HSI Sbjct: 473 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF-----TVDDKEHSIKVSVG 527 Query: 91 TKQI-MLVKKEFPYPCYD---------PATREGDLKLLQLMEKAKINKYVTILHLP---- 136 ++ + ++ +P Y+ P + D+ L++L K K + + + LP Sbjct: 528 GEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEG 587 Query: 137 -KKGDDVKPGTMCQVAGWGRTHNSASWSD-------------TLREVNITIIDRK-VCND 181 + + P T CQ + D T +EV I D+K C Sbjct: 588 TTRALRLPPTTTCQQ----QKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCER 643 Query: 182 RNHY--------NFNPVIGMNMVCAGSLRGGRD--SCNGDSGSPLLCEG----VFRGVTS 227 Y + + V+ +C G + D +C GDSG PL+ + GV S Sbjct: 644 DAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVIS 703 Query: 228 FGLENKCGDPRG 239 +G+ + C + + Sbjct: 704 WGVVDVCKNQKR 715 >1AKS-B nrPDB Length = 98 Score = 134 bits (337), Expect = 4e-32, Method: Composition-based stats. Identities = 34/104 (32%), Positives = 53/104 (50%), Gaps = 7/104 (6%) Query: 157 HNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPL 216 + +S+ L+ + ++ C + I NM+C G L+GG+DSC GDSG P+ Sbjct: 1 SSGSSYPSLLQCLKAPVLSNSSCKSS----YPGQITGNMICVGFLQGGKDSCQGDSGGPV 56 Query: 217 LCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 +C G +G+ S+G C PGVY + ++NWI TI Sbjct: 57 VCNGQLQGIVSWGY--GCAQKNKPGVYTKVC-NYVNWIQQTIAA 97 >2KAI-A nrPDB Length = 80 Score = 119 bits (300), Expect = 9e-28, Method: Composition-based stats. Identities = 31/79 (39%), Positives = 42/79 (53%), Gaps = 1/79 (1%) Query: 29 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 88 IIGG E +S P+ V + C G L+ WVLTAAHC N +V LG H++ Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQCGGVLVNPKWVLTAAHCK-NDNYEVWLGRHNLFEN 59 Query: 89 EPTKQIMLVKKEFPYPCYD 107 E T Q V +FP+P ++ Sbjct: 60 ENTAQFFGVTADFPHPGFN 78 >1EPT-B nrPDB Length = 82 Score = 110 bits (276), Expect = 5e-25, Method: Composition-based stats. Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 2/84 (2%) Query: 74 KRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTIL 133 R QV LG H+I E +Q + K +P ++ T + D+ L++L A +N V + Sbjct: 1 SRIQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATV 60 Query: 134 HLPKKGDDVKPGTMCQVAGWGRTH 157 LP+ GT C ++GWG T Sbjct: 61 SLPRSC--AAAGTECLISGWGNTK 82 >2HNT-F nrPDB Length = 105 Score = 99.1 bits (246), Expect = 2e-21, Method: Composition-based stats. Identities = 31/106 (29%), Positives = 43/106 (40%), Gaps = 16/106 (15%) Query: 162 WSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGS-LRGGR--DSCNGDSGSPLLC 218 L+ VN+ I++R VC D I NM CAG G+ D+C GDSG P + Sbjct: 2 QPSVLQVVNLPIVERPVCKDSTRIR----ITDNMFCAGYKPDEGKRGDACEGDSGGPFVM 57 Query: 219 E------GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 + G+ S+G C G Y + + WI I Sbjct: 58 KSPFNNRWYQMGIVSWG--EGCDRDGKYGFYTHVFRL-KKWIQKVI 100 >1BBR-E nrPDB Length = 109 Score = 97.2 bits (241), Expect = 6e-21, Method: Composition-based stats. Identities = 29/106 (27%), Positives = 41/106 (38%), Gaps = 16/106 (15%) Query: 162 WSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR---DSCNGDSGSPLLC 218 L+ VN+ +++R VC I NM CAG G D+C GDSG P + Sbjct: 6 QPSVLQVVNLPLVERPVCKASTRIR----ITDNMFCAGYKPGEGKRGDACEGDSGGPFVM 61 Query: 219 E------GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTI 258 + G+ S+G C G Y + + WI I Sbjct: 62 KSPYNNRWYQMGIVSWG--EGCDRDGKYGFYTHVFRL-KKWIQKVI 104 >3RU4-E nrPDB Length = 96 Score = 93.8 bits (232), Expect = 8e-20, Method: Composition-based stats. Identities = 29/104 (27%), Positives = 48/104 (46%), Gaps = 13/104 (12%) Query: 161 SWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCE- 219 + D L++ ++ ++ C + I M+CAG+ G SC GDSG PL+C+ Sbjct: 1 NTPDRLQQASLPLLSNTNCKK----YWGTKIKDAMICAGAS--GVSSCMGDSGGPLVCKK 54 Query: 220 ---GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 G+ S+G C PGVY ++ +NW+ T+ Sbjct: 55 NGAWTLVGIVSWGSST-CSTS-TPGVYARVTAL-VNWVQQTLAA 95 >3F1S-B nrPDB Length = 283 Score = 92.6 bits (229), Expect = 2e-19, Method: Composition-based stats. Identities = 36/160 (22%), Positives = 62/160 (38%), Gaps = 20/160 (12%) Query: 41 PYMVLL-SLDRKTICAGALIAKDWVLTAAHC-NLNKRSQVILGAHSITREEPTKQIMLVK 98 P+ V L + + K C G +I +++VLT A C L++ V R ++ + Sbjct: 65 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITV---KTYFNRTSQDPLMIKIT 121 Query: 99 KEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKG---DDVKPGTMCQVAGWGR 155 + YD E DL LL+L + + P+K + P T ++GW R Sbjct: 122 HVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWAR 181 Query: 156 THNSA-----SWSDTL-------REVNITIIDRKVCNDRN 183 + TL + +N+T+ R C + Sbjct: 182 NGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSS 221 >2JET-C nrPDB Length = 99 Score = 91.4 bits (226), Expect = 3e-19, Method: Composition-based stats. Identities = 29/107 (27%), Positives = 47/107 (43%), Gaps = 13/107 (12%) Query: 158 NSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLL 217 N+ + L++ + I+ C + I M CAG+ G DSC GDSG PL+ Sbjct: 1 NALKTPEKLQQAALPIVSEADCKKS----WGSKITDVMTCAGAS--GVDSCMGDSGGPLV 54 Query: 218 CE----GVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 260 C+ G+ S+G C PGVY ++ + W+ ++ Sbjct: 55 CQKDGVWTLAGIVSWG-SGVCSTS-TPGVYSRVTAL-MPWVQQILEA 98 >3H5C-B nrPDB Length = 317 Score = 90.7 bits (224), Expect = 6e-19, Method: Composition-based stats. Identities = 36/160 (22%), Positives = 62/160 (38%), Gaps = 20/160 (12%) Query: 41 PYMVLL-SLDRKTICAGALIAKDWVLTAAHC-NLNKRSQVILGAHSITREEPTKQIMLVK 98 P+ V L + + K C G +I +++VLT A C L++ V R ++ + Sbjct: 106 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITV---KTYFNRTSQDPLMIKIT 162 Query: 99 KEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKG---DDVKPGTMCQVAGWGR 155 + YD E DL LL+L + + P+K + P T ++GW R Sbjct: 163 HVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWAR 222 Query: 156 THNSA-----SWSDTL-------REVNITIIDRKVCNDRN 183 + TL + +N+T+ R C + Sbjct: 223 NGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSS 262 >2HNT-E nrPDB Length = 81 Score = 81.4 bits (200), Expect = 3e-16, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 36/72 (50%), Gaps = 4/72 (5%) Query: 92 KQIMLVKKEFPYPCYD-PATREGDLKLLQLMEKAKINKYVTILHLPKK---GDDVKPGTM 147 ++I +++K + +P Y+ + D+ L++L + + Y+ + LP + ++ G Sbjct: 3 EKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYK 62 Query: 148 CQVAGWGRTHNS 159 +V GWG + Sbjct: 63 GRVTGWGNLKET 74 >2HNT-C nrPDB Length = 70 Score = 81.4 bits (200), Expect = 4e-16, Method: Composition-based stats. Identities = 23/70 (32%), Positives = 34/70 (48%), Gaps = 11/70 (15%) Query: 29 IIGGNEVTPHSRPYMVLLSLD--RKTICAGALIAKDWVLTAAHCNLNKRSQ--------- 77 I+ G++ P+ V+L ++ +C +LI+ WVLTAAHC L Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 78 VILGAHSITR 87 V +G HS TR Sbjct: 61 VRIGKHSRTR 70 >1P3E-A nrPDB Length = 215 Score = 42.9 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 30/83 (36%), Gaps = 11/83 (13%) Query: 50 RKTICAGALIAKDWVLTAAHCNLNKRSQ-------VILGAHSITREEPTKQIMLVKKEFP 102 + C G LIA + +LT HC N S+ V G + T + + + + Sbjct: 28 GGSSCTGTLIAPNKILTNGHCVYNTASRSYSAKGSVYPGMNDSTAVNGSA---NMTEFYV 84 Query: 103 YPCY-DPATREGDLKLLQLMEKA 124 Y + + D +++ Sbjct: 85 PSGYINTGASQYDFAVIKTDTNI 107 >3LT3-A nrPDB Length = 217 Score = 35.6 bits (81), Expect = 0.025, Method: Composition-based stats. Identities = 34/172 (19%), Positives = 59/172 (34%), Gaps = 36/172 (20%) Query: 56 GALIAKDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDL 115 G +I+ D V+T AH V+ G++++T K + YDP+ D+ Sbjct: 42 GFVISPDRVMTNAH--------VVAGSNNVTVYAGDK---PFEATVV--SYDPSV---DV 85 Query: 116 KLLQLMEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIID 175 +L + + K G V G+ N + +RE I + Sbjct: 86 AILAVPHLPPPPLV-------FAAEPAKTGADVVVLGYPGGGNFTATPARIREA-IRL-- 135 Query: 176 RKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLL-CEGVFRGVT 226 + + Y + ++ D GD+G PL+ G GV Sbjct: 136 ----SGPDIYGDPEPVTRDV-----YTIRADVEQGDAGGPLIDLNGQVLGVV 178 >1DUE-A nrPDB Length = 242 Score = 34.8 bits (79), Expect = 0.043, Method: Composition-based stats. Identities = 28/145 (19%), Positives = 52/145 (35%), Gaps = 20/145 (13%) Query: 21 IPEDVCEKIIGGNEVTPHSRPY--MVLLSLDRKTICAGALIAKDWVLTAAHCNL---NKR 75 +P+++ K+ +E PY + + + +T G LI K+ VLT H Sbjct: 25 LPKELFSKV---DEKDRQKYPYNTIGNVFVKGQTSATGVLIGKNTVLTNRHIAKFANGDP 81 Query: 76 SQVILG----AHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEK---AKINK 128 S+V E VK+ P DL L++L + Sbjct: 82 SKVSFRPSINTDDNGNTETPYGEYEVKEILQEP----FGAGVDLALIRLKPDQNGVSLGD 137 Query: 129 YVTILHLPKKGDDVKPGTMCQVAGW 153 ++ + +D+K G ++ G+ Sbjct: 138 KISPAKI-GTSNDLKDGDKLELIGY 161 >2HRV-A nrPDB Length = 142 Score = 32.5 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 25/67 (37%), Gaps = 7/67 (10%) Query: 167 REVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCN-GDSGSPLLCEGVFRGV 225 R IT+ + + I N++ G C GD G LLC+ G+ Sbjct: 66 RYFPITVTSHDWYEIQESEYYPKHIQYNLLI------GEGPCEPGDCGGKLLCKHGVIGI 119 Query: 226 TSFGLEN 232 + G +N Sbjct: 120 VTAGGDN 126 >4GE0-A nrPDB Length = 194 Score = 31.4 bits (70), Expect = 0.45, Method: Composition-based stats. Identities = 14/90 (15%), Positives = 31/90 (34%), Gaps = 12/90 (13%) Query: 117 LLQLMEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDR 176 L+++ ++ + +P D K + + G G + S + +++V Sbjct: 46 LVKMSRDVEMYANRSYKEIPSADDFAKQYDIAIIPGGGLGAKTLSTTPFVQQV------- 98 Query: 177 KVCNDRNHYNFNPVIGMNMVCAGSLRGGRD 206 + P + M+CAG L Sbjct: 99 -----VKEFYKKPNKWIGMICAGPLTAKTS 123 >3H7V-A nrPDB Length = 330 Score = 31.0 bits (69), Expect = 0.53, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 29/89 (32%), Gaps = 11/89 (12%) Query: 65 LTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKA 124 LT A RS + L R E + + + P P + T D+ L Q Sbjct: 16 LTTAQGVWRSRSGIYL------RLEDEQGQVGYGEIAPLPGWGSETLNADIALCQ----- 64 Query: 125 KINKYVTILHLPKKGDDVKPGTMCQVAGW 153 ++ ++T + + + W Sbjct: 65 QLPGHLTPEIMATIPEALPAAQFGFATAW 93 >5UBM-B nrPDB Length = 152 Score = 31.0 bits (69), Expect = 0.53, Method: Composition-based stats. Identities = 5/23 (21%), Positives = 9/23 (39%) Query: 6 RFLASSLSVVVSLLLIPEDVCEK 28 L L V + +P + E+ Sbjct: 128 EVLGPELPKCVPVCGVPREPFEE 150 >5ILB-A nrPDB Length = 474 Score = 31.0 bits (69), Expect = 0.55, Method: Composition-based stats. Identities = 15/88 (17%), Positives = 27/88 (30%), Gaps = 20/88 (22%) Query: 33 NEVTPHSRPYMVLLSLDRKTICAGA--LIAKDWVLTAAHCNLNKRSQVILGAHSITREEP 90 + +S P+ R+ G+ +I +LT AHC + + + Sbjct: 17 HTAPDYSLPWQ----KQRQFTSTGSAFMIGDGKLLTNAHCVEHD--------TQVKVKRR 64 Query: 91 TKQIMLVKKEFPYPCYDPATREGDLKLL 118 V K + D+ LL Sbjct: 65 GDDRKYVAKVLV------RGVDCDIALL 86 >4FLN-A nrPDB Length = 539 Score = 31.0 bits (69), Expect = 0.55, Method: Composition-based stats. Identities = 15/88 (17%), Positives = 27/88 (30%), Gaps = 20/88 (22%) Query: 33 NEVTPHSRPYMVLLSLDRKTICAGA--LIAKDWVLTAAHCNLNKRSQVILGAHSITREEP 90 + +S P+ R+ G+ +I +LT AHC + + + Sbjct: 57 HTAPDYSLPWQ----KQRQFTSTGSAFMIGDGKLLTNAHCVEHD--------TQVKVKRR 104 Query: 91 TKQIMLVKKEFPYPCYDPATREGDLKLL 118 V K + D+ LL Sbjct: 105 GDDRKYVAKVLV------RGVDCDIALL 126 >2PFE-A nrPDB Length = 186 Score = 30.6 bits (68), Expect = 0.65, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 16/42 (38%), Gaps = 9/42 (21%) Query: 191 IGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLEN 232 + CA GDSG P L +GVTS G + Sbjct: 128 LTRTTACAEG---------GDSGGPWLTGSQAQGVTSGGTGD 160 >2EA3-A nrPDB Length = 189 Score = 30.2 bits (67), Expect = 0.86, Method: Composition-based stats. Identities = 12/23 (52%), Positives = 13/23 (56%) Query: 210 GDSGSPLLCEGVFRGVTSFGLEN 232 GDSG LL +GVTS G N Sbjct: 135 GDSGGSLLAGNQAQGVTSGGSGN 157 >5JYK-A nrPDB Length = 566 Score = 30.2 bits (67), Expect = 0.95, Method: Composition-based stats. Identities = 39/217 (17%), Positives = 72/217 (33%), Gaps = 43/217 (19%) Query: 39 SRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVK 98 S P+ + G +I VLT AH ++ +QV L R TK + V Sbjct: 115 SLPWQRKRQYSSGSS--GFIIGGRRVLTNAH-SVEHHTQVKL----KKRGSDTKYLATVL 167 Query: 99 KEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMCQVAGW---GR 155 E D+ LL + + + + V+ + + GD V G+ G Sbjct: 168 AI---------GTECDIALLTVTDD-EFWEGVSPV---EFGDLPALQDAVTVVGYPIGGD 214 Query: 156 THNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSP 215 T + S ++ R H + + L+ +G+SG P Sbjct: 215 TISVTSG----------VVSRMEILSYVHGSTELL---------GLQIDAAINSGNSGGP 255 Query: 216 -LLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHL 251 +G G+ L+++ + G + + + Sbjct: 256 AFNDKGKCVGIAFQSLKHEDAENIGYVIPTPVIVHFI 292 >2OUA-A nrPDB Length = 188 Score = 30.2 bits (67), Expect = 0.95, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 23/72 (31%), Gaps = 11/72 (15%) Query: 182 RNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPG 241 + VCA GDSG + +GVTS G N C G Sbjct: 122 SYPQGTVHSLTRTSVCAEP---------GDSGGSFISGTQAQGVTSGGSGN-C-RTGGTT 170 Query: 242 VYILLSKKHLNW 253 Y ++ +W Sbjct: 171 FYQEVNPMLNSW 182 >5OJX-A nrPDB Length = 254 Score = 30.2 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 10/40 (25%), Positives = 14/40 (35%) Query: 123 KAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASW 162 A + YV G G C V+G G+ + S Sbjct: 208 PASLADYVKRSASSSTGQRFHDGLECMVSGMGQMRSQDSL 247 >2SFA-A nrPDB Length = 191 Score = 29.8 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 28/79 (35%), Gaps = 11/79 (13%) Query: 154 GRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSG 213 G+T + + L +T ++ V + + + VCA GDSG Sbjct: 100 GQTVQRSGSTTGLHSGRVTGLNATV--NYGGGDIVSGLIQTNVCAEP---------GDSG 148 Query: 214 SPLLCEGVFRGVTSFGLEN 232 L G+TS G N Sbjct: 149 GALFAGSTALGLTSGGSGN 167 >2M5T-A nrPDB Length = 142 Score = 29.8 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 18/53 (33%), Gaps = 1/53 (1%) Query: 178 VCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCN-GDSGSPLLCEGVFRGVTSFG 229 C + Y +L G C GD+G LLC G+ + G Sbjct: 70 ECEAHDWYPVEETQYYPKHIQYNLLIGEGPCVPGDAGGKLLCRHGVIGIITAG 122 >5ILA-A nrPDB Length = 301 Score = 29.4 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 37/214 (17%), Positives = 72/214 (33%), Gaps = 37/214 (17%) Query: 39 SRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVK 98 S P+ + G +I VLT AH ++ +QV L R TK + V Sbjct: 115 SLPWQRKRQYSSGSS--GFIIGGRRVLTNAH-SVEHHTQVKL----KKRGSDTKYLATVL 167 Query: 99 KEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHN 158 E D+ LL + + + + V+ + + GD V G+ + Sbjct: 168 AI---------GTECDIALLTVTDD-EFWEGVSPV---EFGDLPALQDAVTVVGYPIGGD 214 Query: 159 SASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSP-LL 217 + S + ++ R H + + L+ +G+SG P Sbjct: 215 TISVTSG-------VVSRMEILSYVHGSTELL---------GLQIDAAINSGNSGGPAFN 258 Query: 218 CEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHL 251 +G G+ L+++ + G + + + Sbjct: 259 DKGKCVGIAFQSLKHEDAENIGYVIPTPVIVHFI 292 >4V1Y-A nrPDB Length = 494 Score = 28.7 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 11/60 (18%), Positives = 23/60 (38%), Gaps = 7/60 (11%) Query: 59 IAKDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCY-DPATREGDLKL 117 + WV H + V LG H+ + P +++ + + P + + T + L Sbjct: 41 LGDSWV----HVQDGRI--VALGVHAESVPPPADRVIDARGKVVLPGFINAHTHVNQILL 94 >4NSY-A nrPDB Length = 275 Score = 28.3 bits (62), Expect = 3.4, Method: Composition-based stats. Identities = 9/33 (27%), Positives = 12/33 (36%), Gaps = 6/33 (18%) Query: 44 VLLSLDRKTICAGALIAKD------WVLTAAHC 70 S C G+L+ + LTA HC Sbjct: 26 AAYSKQGTMWCTGSLVNNSANDKKMYFLTANHC 58 >3JUS-A nrPDB Length = 461 Score = 28.3 bits (62), Expect = 3.4, Method: Composition-based stats. Identities = 7/22 (31%), Positives = 13/22 (59%) Query: 59 IAKDWVLTAAHCNLNKRSQVIL 80 +++ +LTA+HC K + L Sbjct: 150 LSELIILTASHCLHGKEIRSQL 171 >4NCX-A nrPDB Length = 506 Score = 28.3 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 8/38 (21%), Positives = 15/38 (39%) Query: 115 LKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMCQVAG 152 L L Q + ++ + L +P + P C +G Sbjct: 456 LSLNQTNSETTLSGAMKPLCIPLDQPPMPPNMKCFWSG 493 >1SMP-I nrPDB Length = 101 Score = 28.3 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 8/29 (27%), Positives = 15/29 (51%), Gaps = 2/29 (6%) Query: 59 IAKDWVLTAA--HCNLNKRSQVILGAHSI 85 ++ WVL+ A HC++ + V+ G Sbjct: 11 LSGQWVLSGAEQHCDIRLNTDVLDGTTWK 39 >3RIM-A nrPDB Length = 700 Score = 27.9 bits (61), Expect = 4.3, Method: Composition-based stats. Identities = 10/47 (21%), Positives = 18/47 (38%) Query: 60 AKDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCY 106 +VL+A H +L Q+ LG + + K +P + Sbjct: 76 RDRFVLSAGHSSLTLYIQLYLGGFGLELSDIESLRTWGSKTPGHPEF 122 >3W95-A nrPDB Length = 171 Score = 27.9 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 8/20 (40%), Positives = 11/20 (55%) Query: 210 GDSGSPLLCEGVFRGVTSFG 229 GD+G L C+ G+ S G Sbjct: 129 GDAGGILRCQHGVVGIVSTG 148 >4FVB-A nrPDB Length = 152 Score = 27.9 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 8/20 (40%), Positives = 11/20 (55%) Query: 210 GDSGSPLLCEGVFRGVTSFG 229 GD+G L C+ G+ S G Sbjct: 110 GDAGGILRCQHGVVGIVSTG 129 >5X88-A nrPDB Length = 199 Score = 27.5 bits (60), Expect = 5.4, Method: Composition-based stats. Identities = 10/28 (35%), Positives = 12/28 (42%), Gaps = 5/28 (17%) Query: 50 RKTICAGALIAKDWVLTAAHCNLNKRSQ 77 +C G LI LTAAH R + Sbjct: 166 GDLVCDGTLI-----LTAAHFTYGTRVR 188 >6F74-A nrPDB Length = 598 Score = 27.1 bits (59), Expect = 7.4, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 35/103 (33%), Gaps = 15/103 (14%) Query: 64 VLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLL---QL 120 ++TA HC + + I G P I+L + +P T L + + Sbjct: 272 IVTANHCENSDLFRAIRG------GGPGYGIVLSQHIKVHPNVKAVT-AHRLAIAPRNET 324 Query: 121 MEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWS 163 E + + +LH + + VAG+G S Sbjct: 325 AENKDLLDAIAVLH-----QQLPALSNNGVAGYGFWFRSFPGP 362 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.156 0.555 Lambda K H 0.267 0.0480 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,245,063 Number of Sequences: 36641 Number of extensions: 546884 Number of successful extensions: 2699 Number of sequences better than 10.0: 190 Number of HSP's better than 10.0 without gapping: 329 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 1068 Number of HSP's gapped (non-prelim): 363 length of query: 262 length of database: 10,336,785 effective HSP length: 95 effective length of query: 167 effective length of database: 6,855,890 effective search space: 1144933630 effective search space used: 1144933630 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 59 (27.1 bits)