BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P12532 (417 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1QK1-A nrPDB 787 0.0 4Z9M-A nrPDB 678 0.0 1CRK-A nrPDB 676 0.0 4Q2R-A nrPDB 530 e-151 1U6R-A nrPDB 519 e-148 1QH4-A nrPDB 519 e-148 1VRP-A nrPDB 508 e-144 3JU6-A nrPDB 449 e-126 3L2D-A nrPDB 437 e-123 3JPZ-A nrPDB 425 e-119 4RF9-A nrPDB 298 3e-81 4BG4-B nrPDB 262 2e-70 2J1Q-A nrPDB 260 8e-70 5ZHQ-A nrPDB 259 1e-69 5U8E-A nrPDB 258 3e-69 4GVZ-A nrPDB 252 2e-67 4WO8-A nrPDB 236 2e-62 6FH2-A nrPDB 102 3e-22 2I6E-A nrPDB 31 0.99 1GS5-A nrPDB 31 1.00 2PFR-A nrPDB 30 1.5 3T7B-A nrPDB 30 2.9 2FGC-A nrPDB 29 2.9 3HJE-A nrPDB 28 9.8 >1QK1-A nrPDB Length = 379 Score = 787 bits (2033), Expect = 0.0, Method: Compositional matrix adjust. Identities = 379/379 (100%), Positives = 379/379 (100%) Query: 39 AASERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPG 98 AASERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPG Sbjct: 1 AASERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPG 60 Query: 99 HPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDERY 158 HPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDERY Sbjct: 61 HPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDERY 120 Query: 159 VLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQ 218 VLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQ Sbjct: 121 VLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQ 180 Query: 219 QLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGN 278 QLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGN Sbjct: 181 QLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGN 240 Query: 279 MKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKD 338 MKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKD Sbjct: 241 MKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKD 300 Query: 339 SRFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCER 398 SRFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCER Sbjct: 301 SRFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCER 360 Query: 399 RLERGQDIRIPTPVIHTKH 417 RLERGQDIRIPTPVIHTKH Sbjct: 361 RLERGQDIRIPTPVIHTKH 379 >4Z9M-A nrPDB Length = 392 Score = 678 bits (1749), Expect = 0.0, Method: Compositional matrix adjust. Identities = 320/387 (82%), Positives = 352/387 (90%), Gaps = 1/387 (0%) Query: 27 AAGFLLRPEPVRA-ASERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWT 85 G+LL + V A E+ RL+PPSA+YPDLRKHNNCMA LTPA+YA+L +K TP G+T Sbjct: 3 TTGYLLNRQKVCAEVREQPRLFPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYT 62 Query: 86 LDQCIQTGVDNPGHPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLD 145 LDQCIQTGVDNPGHPFIKTVGMVAGDEE+YEVFADLFDPVI+ RHNGYDPR MKHTTDLD Sbjct: 63 LDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLD 122 Query: 146 ASKIRSGYFDERYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGR 205 ASKI G FDE YVLSSRVRTGRSIRGLSLPPACTRAERREVE V + AL GLKGDLAGR Sbjct: 123 ASKITQGQFDEHYVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGR 182 Query: 206 YYRLSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEE 265 YY+LSEMTE +QQ+LIDDHFLFDKPVSPLLT AGMARDWPDARGIWHN +K+FLIW+NEE Sbjct: 183 YYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEE 242 Query: 266 DHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLR 325 DHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLR Sbjct: 243 DHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLR 302 Query: 326 AGVHIKLPLLSKDSRFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQL 385 AGVH+++P LSKD RF KILENLRLQKRGTGGVDTAA V+DISN+DR+G+SEVELVQ+ Sbjct: 303 AGVHVRIPKLSKDPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQI 362 Query: 386 VIDGVNYLIDCERRLERGQDIRIPTPV 412 VIDGVNYL+DCE++LERGQDI++P P+ Sbjct: 363 VIDGVNYLVDCEKKLERGQDIKVPPPL 389 >1CRK-A nrPDB Length = 380 Score = 676 bits (1745), Expect = 0.0, Method: Compositional matrix adjust. Identities = 312/371 (84%), Positives = 349/371 (94%) Query: 42 ERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPF 101 E+R+L+PPSA+YPDLRKHNNCMA LTPA+YA+L DK TP G++LDQCIQTGVDNPGHPF Sbjct: 4 EKRKLFPPSADYPDLRKHNNCMAECLTPAIYAKLRDKLTPNGYSLDQCIQTGVDNPGHPF 63 Query: 102 IKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDERYVLS 161 IKTVGMVAGDEE+YEVFA++FDPVI+ RHNGYDPRTMKH TDLDASKI G FDERYVLS Sbjct: 64 IKTVGMVAGDEESYEVFAEIFDPVIKARHNGYDPRTMKHHTDLDASKITHGQFDERYVLS 123 Query: 162 SRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLI 221 SRVRTGRSIRGLSLPPAC+RAERREVE VVV AL+GLKGDL+G+YY L+ M+E +QQQLI Sbjct: 124 SRVRTGRSIRGLSLPPACSRAERREVENVVVTALAGLKGDLSGKYYSLTNMSERDQQQLI 183 Query: 222 DDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKR 281 DDHFLFDKPVSPLLT AGMARDWPDARGIWHNN+K+FL+W+NEEDHTRVISMEKGGNMKR Sbjct: 184 DDHFLFDKPVSPLLTCAGMARDWPDARGIWHNNDKTFLVWINEEDHTRVISMEKGGNMKR 243 Query: 282 VFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDSRF 341 VFERFCRGLKEVERLI+ERGWEFMWNERLGY+LTCPSNLGTGLRAGVH+KLP LSKD RF Sbjct: 244 VFERFCRGLKEVERLIKERGWEFMWNERLGYVLTCPSNLGTGLRAGVHVKLPRLSKDPRF 303 Query: 342 PKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLE 401 PKILENLRLQKRGTGGVDTAA V+DISNLDR+G+SEVELVQ+VIDGVNYL+DCE++LE Sbjct: 304 PKILENLRLQKRGTGGVDTAAVADVYDISNLDRMGRSEVELVQIVIDGVNYLVDCEKKLE 363 Query: 402 RGQDIRIPTPV 412 +GQDI++P P+ Sbjct: 364 KGQDIKVPPPL 374 >4Q2R-A nrPDB Length = 381 Score = 530 bits (1365), Expect = e-151, Method: Compositional matrix adjust. Identities = 250/361 (69%), Positives = 294/361 (81%), Gaps = 2/361 (0%) Query: 47 YPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKTVG 106 +P E+PDL HNN MA LTP +YA L K+TP+G+T+D IQTGVDNPGHP+I TVG Sbjct: 14 FPAEDEFPDLSGHNNHMAKVLTPELYAELRAKSTPSGFTVDDVIQTGVDNPGHPYIMTVG 73 Query: 107 MVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGY-FDERYVLSSRVR 165 VAGDEE+Y+VF +LFDP+I++RH GY P T +H TDL+ ++ G D YVLSSRVR Sbjct: 74 CVAGDEESYDVFKELFDPIIEDRHGGYKP-TDEHKTDLNPDNLQGGDDLDPNYVLSSRVR 132 Query: 166 TGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHF 225 TGRSIRG LPP C+R ERR +E++ V+ALS L GDLAGRYY L MTEAEQQQLIDDHF Sbjct: 133 TGRSIRGFCLPPHCSRGERRAIEKLAVEALSSLDGDLAGRYYALKSMTEAEQQQLIDDHF 192 Query: 226 LFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFER 285 LFDKPVSPLL A+GMARDWPDARGIWHN+ K+FL+W+NEEDH RVISM+KGGNMK VF R Sbjct: 193 LFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTR 252 Query: 286 FCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDSRFPKIL 345 FC GL ++E L + + +EFMWN LGYILTCPSNLGTGLRAGVHIKLP L K +FP++L Sbjct: 253 FCNGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPHLGKHEKFPEVL 312 Query: 346 ENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLERGQD 405 + LRLQKRGTGGVDTAA GGVFD+SN DRLG SEVELVQ+V+DGV LI+ E+RLE+GQ Sbjct: 313 KRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEQRLEQGQA 372 Query: 406 I 406 I Sbjct: 373 I 373 >1U6R-A nrPDB Length = 380 Score = 519 bits (1337), Expect = e-148, Method: Compositional matrix adjust. Identities = 246/361 (68%), Positives = 287/361 (79%), Gaps = 2/361 (0%) Query: 47 YPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKTVG 106 Y EYPDL KHNN MA LTP +Y +L DK TP+G+TLD IQTGVDNPGHPFI TVG Sbjct: 13 YKSEEEYPDLSKHNNHMAKVLTPDLYKKLRDKETPSGFTLDDVIQTGVDNPGHPFIMTVG 72 Query: 107 MVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGY-FDERYVLSSRVR 165 VAGDEE+Y VF DLFDP+IQ+RH G+ P T KH TDL+ ++ G D YVLSSRVR Sbjct: 73 CVAGDEESYTVFKDLFDPIIQDRHGGFKP-TDKHKTDLNHENLKGGDDLDPHYVLSSRVR 131 Query: 166 TGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHF 225 TG+SI+G +LPP C+R ERR VE++ V+AL+ L G+ G+YY L MTE EQQQLIDDHF Sbjct: 132 TGKSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTEQEQQQLIDDHF 191 Query: 226 LFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFER 285 LFDKPVSPLL A+GMARDWPDARGIWHN+ KSFL+WVNEEDH RVISMEKGGNMK VF R Sbjct: 192 LFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRR 251 Query: 286 FCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDSRFPKIL 345 FC GL+++E + ++ G FMWNE LGY+LTCPSNLGTGLR GVH+KL LSK +F +IL Sbjct: 252 FCVGLQKIEEIFKKAGHPFMWNEHLGYVLTCPSNLGTGLRGGVHVKLAHLSKHPKFEEIL 311 Query: 346 ENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLERGQD 405 LRLQKRGTGGVDTAA G VFDISN DRLG SEVE VQLV+DGV +++ E++LE+GQ Sbjct: 312 TRLRLQKRGTGGVDTAAVGSVFDISNADRLGSSEVEQVQLVVDGVKLMVEMEKKLEKGQS 371 Query: 406 I 406 I Sbjct: 372 I 372 >1QH4-A nrPDB Length = 380 Score = 519 bits (1337), Expect = e-148, Method: Compositional matrix adjust. Identities = 248/361 (68%), Positives = 289/361 (80%), Gaps = 2/361 (0%) Query: 47 YPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKTVG 106 Y EYPDL HNN MA LT +Y +L D+ T +G+TLD IQTGVDNPGHPFI TVG Sbjct: 13 YSVDDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVG 72 Query: 107 MVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGY-FDERYVLSSRVR 165 VAGDEE+YEVF +LFDPVI++RH GY P T +H TDL+A ++ G D YVLSSRVR Sbjct: 73 CVAGDEESYEVFKELFDPVIEDRHGGYKP-TDEHKTDLNADNLQGGDDLDPNYVLSSRVR 131 Query: 166 TGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHF 225 TGRSIRG LPP C+R ERR +E++ V+AL L GDL G+YY L MT+AEQQQLIDDHF Sbjct: 132 TGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHF 191 Query: 226 LFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFER 285 LFDKPVSPLL A+GMARDWPDARGIWHN+ K+FL+W+NEEDH RVISM+KGGNMK VF R Sbjct: 192 LFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTR 251 Query: 286 FCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDSRFPKIL 345 FC GL ++E L + + +EFMWN LGYILTCPSNLGTGLRAGVHIKLP L K +F ++L Sbjct: 252 FCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEKFGEVL 311 Query: 346 ENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLERGQD 405 + LRLQKRGTGGVDTAA GGVFD+SN DRLG SEVELVQ+V+DGV LI+ E+RLE+GQ Sbjct: 312 KRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKRLEKGQS 371 Query: 406 I 406 I Sbjct: 372 I 372 >1VRP-A nrPDB Length = 381 Score = 508 bits (1307), Expect = e-144, Method: Compositional matrix adjust. Identities = 238/361 (65%), Positives = 287/361 (79%), Gaps = 2/361 (0%) Query: 47 YPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKTVG 106 Y + E+PDL KHNN MA LT +Y +L DK TP+G+TLD IQTGVDNPGHPFI TVG Sbjct: 14 YSAAEEFPDLSKHNNHMAKALTLDIYKKLRDKETPSGFTLDDIIQTGVDNPGHPFIMTVG 73 Query: 107 MVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGY-FDERYVLSSRVR 165 VAGDEE YEVF DLFDPVI++RH GY P T KH TDL+ ++ G D YVLSSRVR Sbjct: 74 CVAGDEECYEVFKDLFDPVIEDRHGGYKP-TDKHKTDLNQENLKGGDDLDPNYVLSSRVR 132 Query: 166 TGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHF 225 TGRSI+G++LPP C+R ERR VE++ +D L+ L G+ G+YY LS M++AEQQQLIDDHF Sbjct: 133 TGRSIKGIALPPHCSRGERRLVEKLCIDGLATLTGEFQGKYYPLSSMSDAEQQQLIDDHF 192 Query: 226 LFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFER 285 LFDKP+SPLL A+GMARDWPD RGIWHNN+K+FL+WVNEEDH RVISM+KGGNMK VF R Sbjct: 193 LFDKPISPLLLASGMARDWPDGRGIWHNNDKTFLVWVNEEDHLRVISMQKGGNMKEVFRR 252 Query: 286 FCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDSRFPKIL 345 FC GLK++E + + G FMWNE LGY+LTCPSNLGTGLR GVH+K+P L K +F ++L Sbjct: 253 FCVGLKKIEDIFVKAGRGFMWNEHLGYVLTCPSNLGTGLRGGVHVKIPHLCKHEKFSEVL 312 Query: 346 ENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLERGQD 405 + RLQKRGTGGVDTAA G ++DISN DRLG SEVE VQ+V+DGV +++ E+RLE G+ Sbjct: 313 KRTRLQKRGTGGVDTAAVGSIYDISNADRLGFSEVEQVQMVVDGVKLMVEMEKRLENGKS 372 Query: 406 I 406 I Sbjct: 373 I 373 >3JU6-A nrPDB Length = 370 Score = 449 bits (1154), Expect = e-126, Method: Compositional matrix adjust. Identities = 215/373 (57%), Positives = 277/373 (74%), Gaps = 6/373 (1%) Query: 40 ASERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGH 99 A+ ++ YP ++P+ H + ++ +LT +YA+L D TP+G+TLD+ IQ GVDNP Sbjct: 2 ANLNQKKYPAKDDFPNFEGHKSLLSKYLTADMYAKLRDVATPSGYTLDRAIQNGVDNPDF 61 Query: 100 PFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDERYV 159 +G++AGDEETY VFADLFDPVI+E HNG+ +T H TDLDASKI D YV Sbjct: 62 H----LGLLAGDEETYTVFADLFDPVIEEYHNGF-KKTDNHKTDLDASKILDDVLDPAYV 116 Query: 160 LSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQ 219 +SSRVRTGR+IRG++L P R+ERR +E++V +AL+ L DL G+YY L +M E QQQ Sbjct: 117 ISSRVRTGRNIRGMALSPHVCRSERRAIEKMVSEALNSLAADLKGKYYSLMKMDEKTQQQ 176 Query: 220 LIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNM 279 LIDDHFLFD+PVS T+ GMARD+PD RGIWHN++K+FL+W+NEEDHTR+ISM+ GGNM Sbjct: 177 LIDDHFLFDRPVSRHFTSGGMARDFPDGRGIWHNDKKNFLVWINEEDHTRIISMQMGGNM 236 Query: 280 KRVFERFCRGLKEVERLIQER-GWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKD 338 K VFERF RGL EVE+ I+++ G EFM N+ LG++LTCPSNLGTG+R VH KLP ++KD Sbjct: 237 KEVFERFTRGLTEVEKHIKDKTGKEFMKNDHLGFVLTCPSNLGTGVRCSVHAKLPHMAKD 296 Query: 339 SRFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCER 398 RF +I +RLQKRGT G T + GGV+DISNLDRLG SEVE V VI GV LI+ E+ Sbjct: 297 KRFEEICTKMRLQKRGTSGEFTESVGGVYDISNLDRLGSSEVEQVNCVIKGVKVLIEMEK 356 Query: 399 RLERGQDIRIPTP 411 +LE+G+ I P Sbjct: 357 KLEKGESIDDLVP 369 >3L2D-A nrPDB Length = 390 Score = 437 bits (1123), Expect = e-123, Method: Compositional matrix adjust. Identities = 211/366 (57%), Positives = 266/366 (72%), Gaps = 2/366 (0%) Query: 47 YPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFI-KTV 105 + + +PDL KHNN MAS LT +Y + DK TP G T D+CIQTGVDNPG+ F K Sbjct: 25 FKAADNFPDLSKHNNVMASQLTKELYEKYWDKVTPNGVTFDKCIQTGVDNPGNKFYGKKT 84 Query: 106 GMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDERYVLSSRVR 165 G V GDE +YE + + FD I+E H+ + P DLD +K+ G F+++YV S R+R Sbjct: 85 GCVFGDEYSYECYKEFFDKCIEEIHH-FKPSDKHPAPDLDHNKLVGGVFEDKYVKSCRIR 143 Query: 166 TGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHF 225 GRS++G+ LPPA +RAERR VE+VV DAL GLKGDLAG+YY L+ M E +Q+QLI+DHF Sbjct: 144 CGRSVKGVCLPPAMSRAERRLVEKVVSDALGGLKGDLAGKYYPLTTMNEKDQEQLIEDHF 203 Query: 226 LFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFER 285 LF+KP LLT +G ARDWPD RGIWHNNEK+FL+W+NEEDH RVISM+KGG++K VF R Sbjct: 204 LFEKPTGALLTTSGCARDWPDGRGIWHNNEKNFLVWINEEDHIRVISMQKGGDLKAVFSR 263 Query: 286 FCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDSRFPKIL 345 F RGL EVERL++E G M N+RLGYI TCP+N+GT +RA VH++L L K RF ++L Sbjct: 264 FARGLLEVERLMKECGHGLMHNDRLGYICTCPTNMGTVVRASVHLRLAFLEKHPRFDEML 323 Query: 346 ENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLERGQD 405 LRL KRGTGG + AT +DISN RLGKSE ELVQ+++DGVN LI C+++LE GQ Sbjct: 324 GKLRLGKRGTGGESSLATDSTYDISNWARLGKSERELVQVLVDGVNLLIACDKKLEAGQS 383 Query: 406 IRIPTP 411 I P Sbjct: 384 IDDMIP 389 >3JPZ-A nrPDB Length = 366 Score = 425 bits (1093), Expect = e-119, Method: Compositional matrix adjust. Identities = 207/356 (58%), Positives = 252/356 (70%), Gaps = 4/356 (1%) Query: 51 AEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKTVGMVAG 110 A +PD H + HL +Y RL K T G T+D+ IQ VDN F +G++AG Sbjct: 9 ANFPDYANHGCVVGRHLNFEMYQRLFGKKTAHGVTVDKVIQPSVDN----FGNCIGLIAG 64 Query: 111 DEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDERYVLSSRVRTGRSI 170 DEE+YEVF +LFD VI E+H G+ P + DLDASK+ G FDE+YV S R+RTGR I Sbjct: 65 DEESYEVFKELFDAVINEKHKGFGPNDSQPAPDLDASKLVGGQFDEKYVKSCRIRTGRGI 124 Query: 171 RGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKP 230 RGL PP+CTR ERREVERV+ AL+GL GDL+G YY LS+MT ++ QLI DHFLF KP Sbjct: 125 RGLCYPPSCTRGERREVERVITTALAGLSGDLSGTYYPLSKMTPEQENQLIADHFLFQKP 184 Query: 231 VSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFERFCRGL 290 L+ + RDWPDARGIWHNNEK+FLIW+NEEDH RVISM+KGGN+K VFERF RGL Sbjct: 185 TGHLMVNSASVRDWPDARGIWHNNEKTFLIWINEEDHMRVISMQKGGNVKAVFERFGRGL 244 Query: 291 KEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDSRFPKILENLRL 350 + +++ G E+MWN+RLGY+ CPSNLGTGLRA VH++L LSK +F I+ L+L Sbjct: 245 NAIAEQMKKNGREYMWNQRLGYLCACPSNLGTGLRASVHVQLHQLSKHPKFEDIVVALQL 304 Query: 351 QKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLERGQDI 406 QKRGTGG TAA V+DISN RL KSE E VQL+IDGV LID E+ LE G+ I Sbjct: 305 QKRGTGGEHTAAVDDVYDISNAARLKKSEREFVQLLIDGVKKLIDMEQALEAGKSI 360 >4RF9-A nrPDB Length = 718 Score = 298 bits (763), Expect = 3e-81, Method: Compositional matrix adjust. Identities = 159/373 (42%), Positives = 226/373 (60%), Gaps = 21/373 (5%) Query: 36 PVRAASERRRLYPPSAEYPDLRKHNNC-----MASHLTPAVYARLCDKTTPTGWTLDQCI 90 P A E + +PD C + +LTP V+ L +K T G TL CI Sbjct: 2 PHMADPETAAKFKSKNAFPDPLNDPKCNPKSLVKKYLTPKVFESLKNKKTKLGITLWDCI 61 Query: 91 QTGVDNPGHPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIR 150 +GV N VG+ AGDEE+Y +F LFD +I++ H+ Y T H +D++ + ++ Sbjct: 62 NSGVVN----LDSGVGVYAGDEESYTLFGPLFDAIIEDYHSPYKLAT-GHNSDMNPAHVK 116 Query: 151 SGYFD--ERYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYR 208 + D RY+ S+R+R RS++G L P T+A R E+E+ VV L+ L GDLAG+YY Sbjct: 117 APDLDPANRYIRSTRIRVARSLKGYGLAPGVTKAHRLEIEKKVVGVLTSLTGDLAGKYYP 176 Query: 209 LSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHT 268 LS M E +QQL+DDHFLF K L AAG+ ++WP+ RGI+HNN+K+FL+W+NEEDH Sbjct: 177 LSGMDEKTRQQLVDDHFLFKKG-DRFLEAAGINKEWPEGRGIYHNNDKTFLVWLNEEDHL 235 Query: 269 RVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGV 328 R+ISMEKG ++ VF R CR + E+++ + F ++ GY+ +CPSNLGTG+RA V Sbjct: 236 RIISMEKGSDIGSVFSRLCRAVNEIDKKLG-----FQHTKKHGYLTSCPSNLGTGMRASV 290 Query: 329 HIKLPLLSKDSRFPKILENLRLQKRGTGGVDTAATG---GVFDISNLDRLGKSEVELVQL 385 H+K+P + F IL +Q RG G + +TG GV+DISN RLG SEV+ VQ Sbjct: 291 HVKIPHAKEHPDFENILTKYHIQARGIHGEHSESTGEDAGVYDISNRRRLGLSEVQCVQD 350 Query: 386 VIDGVNYLIDCER 398 + DGV L++ E+ Sbjct: 351 MYDGVKALMELEK 363 Score = 296 bits (759), Expect = 9e-81, Method: Compositional matrix adjust. Identities = 154/365 (42%), Positives = 231/365 (63%), Gaps = 19/365 (5%) Query: 39 AASERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPG 98 A +++R ++P + P+++ + + +LTP ++ L DK T G +L CI +GV+N Sbjct: 365 AIAKKRSVFPEVLKNPEVK---SLLRKYLTPELFDSLKDKKTAKGISLYDCINSGVEN-- 419 Query: 99 HPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDER- 157 + G+ AGDEE Y +FA LFD ++++ H+ Y KHT+D++ K+ + D Sbjct: 420 --LDSSCGVYAGDEECYTLFAPLFDKIVEDYHSPY-KLANKHTSDMNPEKVDAPNLDPEG 476 Query: 158 -YVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAE 216 Y+ S+R+R R+++G +L P TR ER ++ER VV LS L GDLAG+YY L+ M EA Sbjct: 477 TYIRSTRIRVARNVKGYALTPGLTRNERLDIERKVVGVLSSLTGDLAGQYYPLTGMDEAT 536 Query: 217 QQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKG 276 +Q+L++DHFLF K L AAG+ + WP+ RGI+HNN+K+FL+W+NEED R+ISMEKG Sbjct: 537 RQKLVNDHFLFKKG-DRFLEAAGVNKLWPEGRGIFHNNDKTFLVWINEEDQLRIISMEKG 595 Query: 277 GNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLS 336 ++ VF R CR + E+++ + F + GY+ CP+NLGTG+RA VH+K+P S Sbjct: 596 SDIGSVFGRLCRAVNEIDKQLG-----FQHTDAHGYLSGCPTNLGTGMRASVHVKIPKAS 650 Query: 337 KDSRFPKILENLRLQKRGTGGVDTAATG---GVFDISNLDRLGKSEVELVQLVIDGVNYL 393 F KI + +Q RG G + +TG GVFDISN RLG SEV+ VQ + +GV L Sbjct: 651 AHPDFQKICDEFHIQARGIHGEHSVSTGEDAGVFDISNRRRLGLSEVQCVQDMYNGVKKL 710 Query: 394 IDCER 398 ++ E+ Sbjct: 711 LEIEK 715 >4BG4-B nrPDB Length = 356 Score = 262 bits (669), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 148/356 (41%), Positives = 215/356 (60%), Gaps = 17/356 (4%) Query: 51 AEYPDLRKHNNC---MASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKTVGM 107 A + L +C + +LT V+ +L DK T G TL IQ+GV+N VG+ Sbjct: 12 AGFKKLEAATDCRSLLKKYLTKDVFDKLKDKKTSLGATLLDVIQSGVEN----LDSGVGI 67 Query: 108 VAGDEETYEVFADLFDPVIQERHNGYDPRTMKH-TTDL-DASKIRSGYFDERYVLSSRVR 165 A D E Y +FA LFDP+I++ H G+ +T KH D D + + + ++V+S+RVR Sbjct: 68 YAPDAEAYTLFAPLFDPIIEDYHVGF-KQTDKHPNKDFGDVNSFVNVDPEGKFVISTRVR 126 Query: 166 TGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHF 225 GRS++G P T ++ +E+E V LS L+G+L G YY L+ M++ QQ+LIDDHF Sbjct: 127 CGRSMQGYPFNPCLTESQYKEMEAKVSSTLSSLEGELKGTYYPLTGMSKEVQQKLIDDHF 186 Query: 226 LFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFER 285 LF K L AA R WP RGI+HN+ K+FL+WVNEEDH R+ISM+ GG++ +VF R Sbjct: 187 LF-KEGDRFLQAANACRYWPAGRGIYHNDNKTFLVWVNEEDHLRIISMQMGGDLGQVFRR 245 Query: 286 FCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKD-SRFPKI 344 + E+E+ I F ++RLG++ CP+NLGT +RA VHIKLP L+ + + ++ Sbjct: 246 LTSAVNEIEKRIP-----FSHHDRLGFLTFCPTNLGTTVRASVHIKLPKLAANREKLEEV 300 Query: 345 LENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRL 400 LQ RGT G T A GG++DISN R+G +E + V+ + DG+ LI E+ + Sbjct: 301 AGKYNLQVRGTRGEHTEAEGGIYDISNKRRMGLTEFQAVKEMQDGILELIKIEKEM 356 >2J1Q-A nrPDB Length = 357 Score = 260 bits (664), Expect = 8e-70, Method: Compositional matrix adjust. Identities = 145/352 (41%), Positives = 206/352 (58%), Gaps = 15/352 (4%) Query: 51 AEYPDLRKHNNC---MASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKTVGM 107 A + L+ ++C + +LT V+ +L K T G TL IQ+GV+N +G+ Sbjct: 12 AAFAKLQNASDCHSLLKKYLTKEVFDQLKGKQTKMGATLMDVIQSGVEN----LDSGIGV 67 Query: 108 VAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDL-DASKIRSGYFDERYVLSSRVRT 166 A D E+Y +FA L DP+I++ H G+ P + D D + D++YV+S+RVR Sbjct: 68 YAPDAESYTLFAALLDPIIEDYHKGFKPSDKQPPKDSGDLNTFIDVDPDKKYVISTRVRC 127 Query: 167 GRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHFL 226 GRS+ G P + + E+E V L + G+L G+YY L+ MT+ Q+QLIDDHFL Sbjct: 128 GRSLEGYPFNPCLKKQQYEEMESRVKGQLESMSGELRGKYYPLTGMTKETQKQLIDDHFL 187 Query: 227 FDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFERF 286 F K L AA + WP RGI+HN+ K+FL+WVNEEDH R+ISM+KGGN+K VF R Sbjct: 188 F-KEGDRFLQAAHACKFWPTGRGIYHNDAKTFLVWVNEEDHLRIISMQKGGNLKEVFGRL 246 Query: 287 CRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKD-SRFPKIL 345 + +E ++ F ++RLG++ CP+NLGT +RA VHIKLP L D + ++ Sbjct: 247 VTAVGVIEEKVK-----FSRDDRLGFLTFCPTNLGTTIRASVHIKLPKLGADRKKLEEVA 301 Query: 346 ENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCE 397 LQ RGT G + + GV+DISN RLG SE E V+ + DG+ LI E Sbjct: 302 AKYNLQVRGTAGEHSDSPDGVYDISNKRRLGLSEYEAVKEMQDGILELIKAE 353 >5ZHQ-A nrPDB Length = 357 Score = 259 bits (663), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 146/355 (41%), Positives = 214/355 (60%), Gaps = 17/355 (4%) Query: 53 YPDLRKHNNC---MASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKTVGMVA 109 + L +C + +LT +V+ +L K T G TL IQ+GV+N VG+ A Sbjct: 14 FKKLEAATDCKSLLKKYLTKSVFDQLKGKKTSLGATLLDVIQSGVEN----LDSGVGVYA 69 Query: 110 GDEETYEVFADLFDPVIQERHNGYDPRTMKH-TTDL-DASKIRSGYFDERYVLSSRVRTG 167 D E Y +FA LFDP+I++ H G+ +T KH D D ++ + D ++V+S+RVR G Sbjct: 70 PDAEAYTLFAPLFDPIIEDYHKGF-KQTDKHPNKDFGDVNQFVNVDPDGKFVISTRVRCG 128 Query: 168 RSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLF 227 RS+ G P T A+ +E+E V LS L+G+L G YY L+ MT+ QQ+LIDDHFLF Sbjct: 129 RSMEGYPFNPCLTEAQYKEMESKVSSTLSNLEGELKGTYYPLTGMTKDVQQKLIDDHFLF 188 Query: 228 DKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFERFC 287 K L AA R WP RGI+HN+ K+FL+W +EEDH R+ISM+ GG++ +V+ R Sbjct: 189 -KEGDRFLQAANACRYWPTGRGIYHNDNKTFLVWCDEEDHLRIISMQMGGDLGQVYRRLV 247 Query: 288 RGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKD-SRFPKILE 346 + E+E+ + F ++RLG++ CP+NLGT +RA VHIKLP L+ + + ++ Sbjct: 248 SAVNEIEKRV-----PFSHHDRLGFLTFCPTNLGTTVRASVHIKLPKLAANREKLEEVAG 302 Query: 347 NLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLE 401 LQ RGT G T A GGV+DISN R+G +E + V+ + DG+ LI E+ ++ Sbjct: 303 KYSLQVRGTRGEHTEAEGGVYDISNKRRMGLTEFQAVKEMQDGILELIKIEKEMQ 357 >5U8E-A nrPDB Length = 384 Score = 258 bits (659), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 143/352 (40%), Positives = 204/352 (57%), Gaps = 15/352 (4%) Query: 51 AEYPDLRKHNNC---MASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKTVGM 107 A + L+ +C + +L V+ + T G TL CIQ+GV+N VG+ Sbjct: 39 AGFKKLQDATDCKSLLKKYLNREVFDQCKSLKTALGATLLDCIQSGVEN----LDSGVGI 94 Query: 108 VAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDL-DASKIRSGYFDERYVLSSRVRT 166 A D E Y +FA +F+P+I++ H G+ P TD D + I + +YV+S+ VR Sbjct: 95 YAPDAEAYTLFAPIFNPIIEDYHEGFKPTDKHPPTDFGDINTIVNVDPSGKYVVSTHVRC 154 Query: 167 GRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHFL 226 GRS++G P T A +E+E V +G+L G+YY L+ M +A QQQLIDDHFL Sbjct: 155 GRSLKGYPFNPCLTEANYKEMEDKVSAIFGTFEGELKGKYYPLTGMDKATQQQLIDDHFL 214 Query: 227 FDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFERF 286 F K L AA R WP RGI+HN+ K+FL+WVNEEDH R+ISM+KGG++K +F+R Sbjct: 215 F-KEGDRFLQAANACRYWPTGRGIYHNDAKTFLVWVNEEDHLRIISMQKGGDLKTIFQRL 273 Query: 287 CRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDSR-FPKIL 345 + +E + F ++RLG++ CP+NLGT +RA VHI LP L+KD + I Sbjct: 274 VNAVNTIESKL-----PFSRDDRLGFLTFCPTNLGTTIRASVHIALPKLAKDKKQLEAIA 328 Query: 346 ENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCE 397 LQ RGT G T + GGV+DISN R+G +E + V+ + DG+ +I E Sbjct: 329 AKFNLQVRGTRGEHTESEGGVYDISNKRRMGLTEYQAVKEMQDGILEMIKME 380 >4GVZ-A nrPDB Length = 357 Score = 252 bits (644), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 143/354 (40%), Positives = 208/354 (58%), Gaps = 17/354 (4%) Query: 51 AEYPDLRKHNNC---MASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKTVGM 107 A + L++ ++C + HLT V+ + +K T G TL IQ+GV+N VG+ Sbjct: 12 AGFKKLQEASDCKSLLKKHLTKDVFDSIKNKKTGMGATLLDVIQSGVEN----LDSGVGI 67 Query: 108 VAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDL--DASKIRSGYFDERYVLSSRVR 165 A D E+Y F LFDP+I + H G+ T KH D + + ++++S+RVR Sbjct: 68 YAPDAESYRTFGPLFDPIIDDYHGGF-KLTDKHPPKQWGDINTLVGLDPAGQFIISTRVR 126 Query: 166 TGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHF 225 GRS++G P T + +E+E V LS ++ +L G YY L+ M++A QQQLIDDHF Sbjct: 127 CGRSLQGYPFNPCLTAEQYKEMEEKVSSTLSSMEDELKGTYYPLTGMSKATQQQLIDDHF 186 Query: 226 LFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFER 285 LF K L A R WP RGI+HN+ K+FL+WVNEEDH R+ISM+KGG++K V++R Sbjct: 187 LF-KEGDRFLQTANACRYWPTGRGIFHNDAKTFLVWVNEEDHLRIISMQKGGDLKTVYKR 245 Query: 286 FCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDSR-FPKI 344 + +E + F ++R G++ CP+NLGT +RA VHI+LP L+KD + I Sbjct: 246 LVTAVDNIESKL-----PFSHDDRFGFLTFCPTNLGTTMRASVHIQLPKLAKDRKVLEDI 300 Query: 345 LENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCER 398 LQ RGT G T + GGV+DISN RLG +E + V+ + DG+ +I E+ Sbjct: 301 ASKFNLQVRGTRGEHTESEGGVYDISNKRRLGLTEYQAVREMQDGILEMIKMEK 354 >4WO8-A nrPDB Length = 716 Score = 236 bits (601), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 133/340 (39%), Positives = 198/340 (58%), Gaps = 17/340 (5%) Query: 66 HLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKTVGMVAGDEETYEVFADLFDPV 125 +LTP + + K T G TL I+ G N +++ G+ E Y F D DP+ Sbjct: 389 YLTPEIIKKYDGKRTTHGATLAHMIRNGAYNN-----RSICPRTGEAECYSTFIDYLDPL 443 Query: 126 IQERHNGYDPRTMKHT--TDLDASKIRSGYFDE--RYVLSSRVRTGRSIRGLSLPPACTR 181 I + H G KH T D SK+ G D ++++S+RVR GRS+ G P ++ Sbjct: 444 ICDYH-GVKDSAFKHPAPTFGDLSKLPFGDLDPTGKFIVSTRVRVGRSVEGFLFPTIMSK 502 Query: 182 AERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMA 241 +R ++E+V+ AL GL G+ AG YY L++M E +++QL++DHFLF K P+L AG Sbjct: 503 TDRIKLEQVISGALKGLTGEHAGTYYPLTDMKEEDRKQLVEDHFLF-KNDDPVLRDAGGY 561 Query: 242 RDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERG 301 RDWP RGI+HNN K+FL+WV EEDH R+ISM++GGN+ V++R G+ + + ++ Sbjct: 562 RDWPVGRGIFHNNSKTFLVWVCEEDHMRIISMQQGGNLAAVYKRLIEGINAIGKSMK--- 618 Query: 302 WEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKD-SRFPKILENLRLQKRGTGGVDT 360 F +++ GYI CPSNLGT +RA V +K+P LS + +I LQ RG G T Sbjct: 619 --FAHSDKYGYITCCPSNLGTSMRASVLLKIPKLSSQPKKLDEICAKYMLQARGLYGEHT 676 Query: 361 AATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRL 400 + G +DISN RLG +E++ + +GV +I+ E+ L Sbjct: 677 ESPDGTYDISNKRRLGLTELQAAHEMAEGVAKMIEIEKGL 716 Score = 233 bits (594), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 133/350 (38%), Positives = 194/350 (55%), Gaps = 15/350 (4%) Query: 55 DLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKTVGMVAGDEET 114 D R H+ +LT + + T G TL QC+ T NPG ++ D Sbjct: 16 DERNHS-LTKKYLTDDIVKKYQATKTSLGGTLAQCVNTNAYNPGALLPRSC-----DLNA 69 Query: 115 YEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDERY---VLSSRVRTGRSIR 171 YE F D FD VI + H D + ++ K S Y V+S+RVR GR++ Sbjct: 70 YETFRDFFDAVIADYHKVPDGKIQHPKSNFGDLKSLSFTDLNTYGNLVVSTRVRLGRTVE 129 Query: 172 GLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPV 231 G P T+ R E+E + AL L G+ G YY L+ M+E ++ +L++DHFLF Sbjct: 130 GFGFGPTLTKETRIELENKISTALHNLSGEYEGTYYPLTGMSEEDRIKLVNDHFLFRNDD 189 Query: 232 SPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFERFCRGLK 291 + L A G DWP RGI+ N +K+FL+W+NEEDH RVISM+KGG + V++R ++ Sbjct: 190 NVLRDAGGYI-DWPTGRGIFINKQKNFLVWINEEDHIRVISMQKGGGLTAVYKRLADAIQ 248 Query: 292 EVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDSRFPKILENLRLQ 351 E+ + ++ F +N+RLG+I CPSNLGT LRA VH K+P+L+ F +I E +Q Sbjct: 249 ELSKSLK-----FAFNDRLGFITFCPSNLGTTLRASVHAKIPMLASLPNFKEICEKHGIQ 303 Query: 352 KRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLE 401 RGT G T + GG++D+SN RLG +E++ V + GV L++ E L+ Sbjct: 304 PRGTHGEHTESVGGIYDLSNKRRLGLTELDAVTEMHSGVRALLELEVMLQ 353 >6FH2-A nrPDB Length = 366 Score = 102 bits (254), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 81/245 (33%), Positives = 121/245 (49%), Gaps = 21/245 (8%) Query: 159 VLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRY--YRLSEMTEAE 216 VLSSR+R R+I P + E +++ + A AGR+ ++SE+ E Sbjct: 28 VLSSRIRLARNIVDFRFPTLFSSEEAKQIVALFERAFVHRPYGEAGRFELLKMSELQPIE 87 Query: 217 QQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKG 276 ++ L++ H +SP L A D P + NE+ I +NEEDH R+ + G Sbjct: 88 KRVLVEKHL-----ISPHL-----AEDSPFGACLLSENEE-ISIMINEEDHIRIQCLFPG 136 Query: 277 GNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLS 336 + E E++ I E + ++ERLGY+ +CP+N+GTGLRA V + LP L Sbjct: 137 LQLAEALE----AASELDDWI-EGHVNYAFDERLGYLTSCPTNVGTGLRASVMMHLPALV 191 Query: 337 KDSRFPKI---LENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYL 393 + +I + L L RGT G + A G +F ISN LGKSE ++V + V L Sbjct: 192 LTQQINRIIPAINQLGLVVRGTYGEGSEALGNIFQISNQITLGKSEEDIVADLHTIVEQL 251 Query: 394 IDCER 398 I ER Sbjct: 252 IAQER 256 >2I6E-A nrPDB Length = 301 Score = 31.2 bits (69), Expect = 0.99, Method: Compositional matrix adjust. Identities = 23/96 (23%), Positives = 42/96 (43%), Gaps = 19/96 (19%) Query: 235 LTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKG---------GNMKRVFER 285 +T +A++W D G + +F +W +D+ ++ + G++ V +R Sbjct: 185 ITVTDLAQEWFDLTG----HPFTFAVWAYRKDNPPPAALLQAMREARRRGIGHLAEVSQR 240 Query: 286 FCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLG 321 L ER++Q ++WN R Y L P LG Sbjct: 241 HAEKLGLPERVVQH----YLWNFR--YHLEAPDRLG 270 >1GS5-A nrPDB Length = 258 Score = 30.8 bits (68), Expect = 1.00, Method: Compositional matrix adjust. Identities = 17/48 (35%), Positives = 27/48 (56%) Query: 195 LSGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMAR 242 LS + G L G+ R++EMT A+ +QLI+ + D + + A AR Sbjct: 179 LSDVSGILDGKGQRIAEMTAAKAEQLIEQGIITDGMIVKVNAALDAAR 226 >2PFR-A nrPDB Length = 294 Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust. Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 1/42 (2%) Query: 355 TGGVDTAATGGVFDISNLDRLGKSEVELV-QLVIDGVNYLID 395 T G T GG F I +++ V L+ Q+ IDG NY++D Sbjct: 85 TIGFQTTMLGGYFYIPPVNKYSTGMVHLLLQVTIDGRNYIVD 126 >3T7B-A nrPDB Length = 260 Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 2/64 (3%) Query: 195 LSGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDW--PDARGIWH 252 LS + G L G+ R++EMT + +QLI + D V + A AR P W Sbjct: 181 LSDVSGILDGKGQRIAEMTAQKAEQLIAQGIITDGMVVKVNAALDAARSLGRPVDIASWR 240 Query: 253 NNEK 256 ++E+ Sbjct: 241 HSEQ 244 >2FGC-A nrPDB Length = 193 Score = 29.3 bits (64), Expect = 2.9, Method: Compositional matrix adjust. Identities = 19/74 (25%), Positives = 30/74 (40%), Gaps = 2/74 (2%) Query: 43 RRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFI 102 R LY +R+H M H P V ++ + G+ + + PG Sbjct: 14 RENLYFQGHMTDQIREHLVSMLVHNKPGVMRKVANLFARRGFNISSITVGESETPG--LS 71 Query: 103 KTVGMVAGDEETYE 116 + V MV GD++T E Sbjct: 72 RLVIMVKGDDKTIE 85 >3HJE-A nrPDB Length = 704 Score = 27.7 bits (60), Expect = 9.8, Method: Compositional matrix adjust. Identities = 14/40 (35%), Positives = 22/40 (55%), Gaps = 4/40 (10%) Query: 242 RDWPDARGIWHNNE----KSFLIWVNEEDHTRVISMEKGG 277 RD+P R + NE + L WV E+ H++++S E G Sbjct: 179 RDYPSYRRFFAVNELIAVRQELEWVFEDSHSKILSFEVDG 218 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1QK1-A nrPDB 638 0.0 4Z9M-A nrPDB 637 0.0 1CRK-A nrPDB 622 e-179 4Q2R-A nrPDB 604 e-173 1U6R-A nrPDB 600 e-172 1QH4-A nrPDB 600 e-172 1VRP-A nrPDB 596 e-171 3L2D-A nrPDB 564 e-161 3JU6-A nrPDB 553 e-158 3JPZ-A nrPDB 549 e-157 4BG4-B nrPDB 518 e-147 5ZHQ-A nrPDB 515 e-146 5U8E-A nrPDB 510 e-145 4GVZ-A nrPDB 504 e-143 2J1Q-A nrPDB 501 e-142 4RF9-A nrPDB 500 e-142 4WO8-A nrPDB 442 e-124 6FH2-A nrPDB 262 2e-70 Sequences not found previously or not previously below threshold: 6D1P-A nrPDB 33 0.26 1NYT-A nrPDB 31 1.1 5B6K-A nrPDB 31 1.3 3SL2-A nrPDB 30 2.1 3U1H-A nrPDB 30 2.2 5OGQ-A nrPDB 30 2.5 4I05-A nrPDB 30 2.5 4I04-A nrPDB 30 2.5 3IO3-A nrPDB 30 3.0 5LOL-A nrPDB 29 3.6 1GZU-A nrPDB 29 4.0 1A8Y-A nrPDB 29 5.1 2PSB-A nrPDB 28 8.6 CONVERGED! >1QK1-A nrPDB Length = 379 Score = 638 bits (1646), Expect = 0.0, Method: Composition-based stats. Identities = 379/379 (100%), Positives = 379/379 (100%) Query: 39 AASERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPG 98 AASERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPG Sbjct: 1 AASERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPG 60 Query: 99 HPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDERY 158 HPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDERY Sbjct: 61 HPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDERY 120 Query: 159 VLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQ 218 VLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQ Sbjct: 121 VLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQ 180 Query: 219 QLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGN 278 QLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGN Sbjct: 181 QLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGN 240 Query: 279 MKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKD 338 MKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKD Sbjct: 241 MKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKD 300 Query: 339 SRFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCER 398 SRFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCER Sbjct: 301 SRFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCER 360 Query: 399 RLERGQDIRIPTPVIHTKH 417 RLERGQDIRIPTPVIHTKH Sbjct: 361 RLERGQDIRIPTPVIHTKH 379 >4Z9M-A nrPDB Length = 392 Score = 637 bits (1644), Expect = 0.0, Method: Composition-based stats. Identities = 320/387 (82%), Positives = 352/387 (90%), Gaps = 1/387 (0%) Query: 27 AAGFLLRPEPVRA-ASERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWT 85 G+LL + V A E+ RL+PPSA+YPDLRKHNNCMA LTPA+YA+L +K TP G+T Sbjct: 3 TTGYLLNRQKVCAEVREQPRLFPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYT 62 Query: 86 LDQCIQTGVDNPGHPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLD 145 LDQCIQTGVDNPGHPFIKTVGMVAGDEE+YEVFADLFDPVI+ RHNGYDPR MKHTTDLD Sbjct: 63 LDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLD 122 Query: 146 ASKIRSGYFDERYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGR 205 ASKI G FDE YVLSSRVRTGRSIRGLSLPPACTRAERREVE V + AL GLKGDLAGR Sbjct: 123 ASKITQGQFDEHYVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGR 182 Query: 206 YYRLSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEE 265 YY+LSEMTE +QQ+LIDDHFLFDKPVSPLLT AGMARDWPDARGIWHN +K+FLIW+NEE Sbjct: 183 YYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEE 242 Query: 266 DHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLR 325 DHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLR Sbjct: 243 DHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLR 302 Query: 326 AGVHIKLPLLSKDSRFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQL 385 AGVH+++P LSKD RF KILENLRLQKRGTGGVDTAA V+DISN+DR+G+SEVELVQ+ Sbjct: 303 AGVHVRIPKLSKDPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQI 362 Query: 386 VIDGVNYLIDCERRLERGQDIRIPTPV 412 VIDGVNYL+DCE++LERGQDI++P P+ Sbjct: 363 VIDGVNYLVDCEKKLERGQDIKVPPPL 389 >1CRK-A nrPDB Length = 380 Score = 622 bits (1605), Expect = e-179, Method: Composition-based stats. Identities = 312/373 (83%), Positives = 349/373 (93%) Query: 40 ASERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGH 99 E+R+L+PPSA+YPDLRKHNNCMA LTPA+YA+L DK TP G++LDQCIQTGVDNPGH Sbjct: 2 VHEKRKLFPPSADYPDLRKHNNCMAECLTPAIYAKLRDKLTPNGYSLDQCIQTGVDNPGH 61 Query: 100 PFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDERYV 159 PFIKTVGMVAGDEE+YEVFA++FDPVI+ RHNGYDPRTMKH TDLDASKI G FDERYV Sbjct: 62 PFIKTVGMVAGDEESYEVFAEIFDPVIKARHNGYDPRTMKHHTDLDASKITHGQFDERYV 121 Query: 160 LSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQ 219 LSSRVRTGRSIRGLSLPPAC+RAERREVE VVV AL+GLKGDL+G+YY L+ M+E +QQQ Sbjct: 122 LSSRVRTGRSIRGLSLPPACSRAERREVENVVVTALAGLKGDLSGKYYSLTNMSERDQQQ 181 Query: 220 LIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNM 279 LIDDHFLFDKPVSPLLT AGMARDWPDARGIWHNN+K+FL+W+NEEDHTRVISMEKGGNM Sbjct: 182 LIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNNDKTFLVWINEEDHTRVISMEKGGNM 241 Query: 280 KRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDS 339 KRVFERFCRGLKEVERLI+ERGWEFMWNERLGY+LTCPSNLGTGLRAGVH+KLP LSKD Sbjct: 242 KRVFERFCRGLKEVERLIKERGWEFMWNERLGYVLTCPSNLGTGLRAGVHVKLPRLSKDP 301 Query: 340 RFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERR 399 RFPKILENLRLQKRGTGGVDTAA V+DISNLDR+G+SEVELVQ+VIDGVNYL+DCE++ Sbjct: 302 RFPKILENLRLQKRGTGGVDTAAVADVYDISNLDRMGRSEVELVQIVIDGVNYLVDCEKK 361 Query: 400 LERGQDIRIPTPV 412 LE+GQDI++P P+ Sbjct: 362 LEKGQDIKVPPPL 374 >4Q2R-A nrPDB Length = 381 Score = 604 bits (1557), Expect = e-173, Method: Composition-based stats. Identities = 251/367 (68%), Positives = 295/367 (80%), Gaps = 2/367 (0%) Query: 46 LYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKTV 105 +P E+PDL HNN MA LTP +YA L K+TP+G+T+D IQTGVDNPGHP+I TV Sbjct: 13 RFPAEDEFPDLSGHNNHMAKVLTPELYAELRAKSTPSGFTVDDVIQTGVDNPGHPYIMTV 72 Query: 106 GMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGY-FDERYVLSSRV 164 G VAGDEE+Y+VF +LFDP+I++RH GY P T +H TDL+ ++ G D YVLSSRV Sbjct: 73 GCVAGDEESYDVFKELFDPIIEDRHGGYKP-TDEHKTDLNPDNLQGGDDLDPNYVLSSRV 131 Query: 165 RTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDH 224 RTGRSIRG LPP C+R ERR +E++ V+ALS L GDLAGRYY L MTEAEQQQLIDDH Sbjct: 132 RTGRSIRGFCLPPHCSRGERRAIEKLAVEALSSLDGDLAGRYYALKSMTEAEQQQLIDDH 191 Query: 225 FLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFE 284 FLFDKPVSPLL A+GMARDWPDARGIWHN+ K+FL+W+NEEDH RVISM+KGGNMK VF Sbjct: 192 FLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFT 251 Query: 285 RFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDSRFPKI 344 RFC GL ++E L + + +EFMWN LGYILTCPSNLGTGLRAGVHIKLP L K +FP++ Sbjct: 252 RFCNGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPHLGKHEKFPEV 311 Query: 345 LENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLERGQ 404 L+ LRLQKRGTGGVDTAA GGVFD+SN DRLG SEVELVQ+V+DGV LI+ E+RLE+GQ Sbjct: 312 LKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEQRLEQGQ 371 Query: 405 DIRIPTP 411 I P Sbjct: 372 AIDDLMP 378 >1U6R-A nrPDB Length = 380 Score = 600 bits (1548), Expect = e-172, Method: Composition-based stats. Identities = 247/366 (67%), Positives = 288/366 (78%), Gaps = 2/366 (0%) Query: 47 YPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKTVG 106 Y EYPDL KHNN MA LTP +Y +L DK TP+G+TLD IQTGVDNPGHPFI TVG Sbjct: 13 YKSEEEYPDLSKHNNHMAKVLTPDLYKKLRDKETPSGFTLDDVIQTGVDNPGHPFIMTVG 72 Query: 107 MVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGY-FDERYVLSSRVR 165 VAGDEE+Y VF DLFDP+IQ+RH G+ P T KH TDL+ ++ G D YVLSSRVR Sbjct: 73 CVAGDEESYTVFKDLFDPIIQDRHGGFKP-TDKHKTDLNHENLKGGDDLDPHYVLSSRVR 131 Query: 166 TGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHF 225 TG+SI+G +LPP C+R ERR VE++ V+AL+ L G+ G+YY L MTE EQQQLIDDHF Sbjct: 132 TGKSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTEQEQQQLIDDHF 191 Query: 226 LFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFER 285 LFDKPVSPLL A+GMARDWPDARGIWHN+ KSFL+WVNEEDH RVISMEKGGNMK VF R Sbjct: 192 LFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRR 251 Query: 286 FCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDSRFPKIL 345 FC GL+++E + ++ G FMWNE LGY+LTCPSNLGTGLR GVH+KL LSK +F +IL Sbjct: 252 FCVGLQKIEEIFKKAGHPFMWNEHLGYVLTCPSNLGTGLRGGVHVKLAHLSKHPKFEEIL 311 Query: 346 ENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLERGQD 405 LRLQKRGTGGVDTAA G VFDISN DRLG SEVE VQLV+DGV +++ E++LE+GQ Sbjct: 312 TRLRLQKRGTGGVDTAAVGSVFDISNADRLGSSEVEQVQLVVDGVKLMVEMEKKLEKGQS 371 Query: 406 IRIPTP 411 I P Sbjct: 372 IDDMIP 377 >1QH4-A nrPDB Length = 380 Score = 600 bits (1546), Expect = e-172, Method: Composition-based stats. Identities = 249/372 (66%), Positives = 292/372 (78%), Gaps = 2/372 (0%) Query: 41 SERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHP 100 + + Y EYPDL HNN MA LT +Y +L D+ T +G+TLD IQTGVDNPGHP Sbjct: 7 NLLKMKYSVDDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHP 66 Query: 101 FIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGY-FDERYV 159 FI TVG VAGDEE+YEVF +LFDPVI++RH GY P T +H TDL+A ++ G D YV Sbjct: 67 FIMTVGCVAGDEESYEVFKELFDPVIEDRHGGYKP-TDEHKTDLNADNLQGGDDLDPNYV 125 Query: 160 LSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQ 219 LSSRVRTGRSIRG LPP C+R ERR +E++ V+AL L GDL G+YY L MT+AEQQQ Sbjct: 126 LSSRVRTGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQ 185 Query: 220 LIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNM 279 LIDDHFLFDKPVSPLL A+GMARDWPDARGIWHN+ K+FL+W+NEEDH RVISM+KGGNM Sbjct: 186 LIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNM 245 Query: 280 KRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDS 339 K VF RFC GL ++E L + + +EFMWN LGYILTCPSNLGTGLRAGVHIKLP L K Sbjct: 246 KEVFTRFCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHE 305 Query: 340 RFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERR 399 +F ++L+ LRLQKRGTGGVDTAA GGVFD+SN DRLG SEVELVQ+V+DGV LI+ E+R Sbjct: 306 KFGEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKR 365 Query: 400 LERGQDIRIPTP 411 LE+GQ I P Sbjct: 366 LEKGQSIDDLMP 377 >1VRP-A nrPDB Length = 381 Score = 596 bits (1538), Expect = e-171, Method: Composition-based stats. Identities = 239/366 (65%), Positives = 288/366 (78%), Gaps = 2/366 (0%) Query: 47 YPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKTVG 106 Y + E+PDL KHNN MA LT +Y +L DK TP+G+TLD IQTGVDNPGHPFI TVG Sbjct: 14 YSAAEEFPDLSKHNNHMAKALTLDIYKKLRDKETPSGFTLDDIIQTGVDNPGHPFIMTVG 73 Query: 107 MVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGY-FDERYVLSSRVR 165 VAGDEE YEVF DLFDPVI++RH GY P T KH TDL+ ++ G D YVLSSRVR Sbjct: 74 CVAGDEECYEVFKDLFDPVIEDRHGGYKP-TDKHKTDLNQENLKGGDDLDPNYVLSSRVR 132 Query: 166 TGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHF 225 TGRSI+G++LPP C+R ERR VE++ +D L+ L G+ G+YY LS M++AEQQQLIDDHF Sbjct: 133 TGRSIKGIALPPHCSRGERRLVEKLCIDGLATLTGEFQGKYYPLSSMSDAEQQQLIDDHF 192 Query: 226 LFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFER 285 LFDKP+SPLL A+GMARDWPD RGIWHNN+K+FL+WVNEEDH RVISM+KGGNMK VF R Sbjct: 193 LFDKPISPLLLASGMARDWPDGRGIWHNNDKTFLVWVNEEDHLRVISMQKGGNMKEVFRR 252 Query: 286 FCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDSRFPKIL 345 FC GLK++E + + G FMWNE LGY+LTCPSNLGTGLR GVH+K+P L K +F ++L Sbjct: 253 FCVGLKKIEDIFVKAGRGFMWNEHLGYVLTCPSNLGTGLRGGVHVKIPHLCKHEKFSEVL 312 Query: 346 ENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLERGQD 405 + RLQKRGTGGVDTAA G ++DISN DRLG SEVE VQ+V+DGV +++ E+RLE G+ Sbjct: 313 KRTRLQKRGTGGVDTAAVGSIYDISNADRLGFSEVEQVQMVVDGVKLMVEMEKRLENGKS 372 Query: 406 IRIPTP 411 I P Sbjct: 373 IDDLMP 378 >3L2D-A nrPDB Length = 390 Score = 564 bits (1453), Expect = e-161, Method: Composition-based stats. Identities = 213/389 (54%), Positives = 272/389 (69%), Gaps = 2/389 (0%) Query: 24 GSLAAGFLLRPEPVRAASERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTG 83 GS + ++ + + + +PDL KHNN MAS LT +Y + DK TP G Sbjct: 2 GSAIQDYFVKNRVGHSKPWESGKFKAADNFPDLSKHNNVMASQLTKELYEKYWDKVTPNG 61 Query: 84 WTLDQCIQTGVDNPGHPFI-KTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTT 142 T D+CIQTGVDNPG+ F K G V GDE +YE + + FD I+E H+ + P Sbjct: 62 VTFDKCIQTGVDNPGNKFYGKKTGCVFGDEYSYECYKEFFDKCIEEIHH-FKPSDKHPAP 120 Query: 143 DLDASKIRSGYFDERYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDL 202 DLD +K+ G F+++YV S R+R GRS++G+ LPPA +RAERR VE+VV DAL GLKGDL Sbjct: 121 DLDHNKLVGGVFEDKYVKSCRIRCGRSVKGVCLPPAMSRAERRLVEKVVSDALGGLKGDL 180 Query: 203 AGRYYRLSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWV 262 AG+YY L+ M E +Q+QLI+DHFLF+KP LLT +G ARDWPD RGIWHNNEK+FL+W+ Sbjct: 181 AGKYYPLTTMNEKDQEQLIEDHFLFEKPTGALLTTSGCARDWPDGRGIWHNNEKNFLVWI 240 Query: 263 NEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGT 322 NEEDH RVISM+KGG++K VF RF RGL EVERL++E G M N+RLGYI TCP+N+GT Sbjct: 241 NEEDHIRVISMQKGGDLKAVFSRFARGLLEVERLMKECGHGLMHNDRLGYICTCPTNMGT 300 Query: 323 GLRAGVHIKLPLLSKDSRFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVEL 382 +RA VH++L L K RF ++L LRL KRGTGG + AT +DISN RLGKSE EL Sbjct: 301 VVRASVHLRLAFLEKHPRFDEMLGKLRLGKRGTGGESSLATDSTYDISNWARLGKSEREL 360 Query: 383 VQLVIDGVNYLIDCERRLERGQDIRIPTP 411 VQ+++DGVN LI C+++LE GQ I P Sbjct: 361 VQVLVDGVNLLIACDKKLEAGQSIDDMIP 389 >3JU6-A nrPDB Length = 370 Score = 553 bits (1425), Expect = e-158, Method: Composition-based stats. Identities = 215/373 (57%), Positives = 275/373 (73%), Gaps = 6/373 (1%) Query: 40 ASERRRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGH 99 A+ ++ YP ++P+ H + ++ +LT +YA+L D TP+G+TLD+ IQ GVDNP Sbjct: 2 ANLNQKKYPAKDDFPNFEGHKSLLSKYLTADMYAKLRDVATPSGYTLDRAIQNGVDNPDF 61 Query: 100 PFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDERYV 159 G++AGDEETY VFADLFDPVI+E HNG+ T H TDLDASKI D YV Sbjct: 62 HL----GLLAGDEETYTVFADLFDPVIEEYHNGFKK-TDNHKTDLDASKILDDVLDPAYV 116 Query: 160 LSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQ 219 +SSRVRTGR+IRG++L P R+ERR +E++V +AL+ L DL G+YY L +M E QQQ Sbjct: 117 ISSRVRTGRNIRGMALSPHVCRSERRAIEKMVSEALNSLAADLKGKYYSLMKMDEKTQQQ 176 Query: 220 LIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNM 279 LIDDHFLFD+PVS T+ GMARD+PD RGIWHN++K+FL+W+NEEDHTR+ISM+ GGNM Sbjct: 177 LIDDHFLFDRPVSRHFTSGGMARDFPDGRGIWHNDKKNFLVWINEEDHTRIISMQMGGNM 236 Query: 280 KRVFERFCRGLKEVERLIQER-GWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKD 338 K VFERF RGL EVE+ I+++ G EFM N+ LG++LTCPSNLGTG+R VH KLP ++KD Sbjct: 237 KEVFERFTRGLTEVEKHIKDKTGKEFMKNDHLGFVLTCPSNLGTGVRCSVHAKLPHMAKD 296 Query: 339 SRFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCER 398 RF +I +RLQKRGT G T + GGV+DISNLDRLG SEVE V VI GV LI+ E+ Sbjct: 297 KRFEEICTKMRLQKRGTSGEFTESVGGVYDISNLDRLGSSEVEQVNCVIKGVKVLIEMEK 356 Query: 399 RLERGQDIRIPTP 411 +LE+G+ I P Sbjct: 357 KLEKGESIDDLVP 369 >3JPZ-A nrPDB Length = 366 Score = 549 bits (1416), Expect = e-157, Method: Composition-based stats. Identities = 208/363 (57%), Positives = 253/363 (69%), Gaps = 4/363 (1%) Query: 49 PSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKTVGMV 108 A +PD H + HL +Y RL K T G T+D+ IQ VDN F +G++ Sbjct: 7 AKANFPDYANHGCVVGRHLNFEMYQRLFGKKTAHGVTVDKVIQPSVDN----FGNCIGLI 62 Query: 109 AGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDERYVLSSRVRTGR 168 AGDEE+YEVF +LFD VI E+H G+ P + DLDASK+ G FDE+YV S R+RTGR Sbjct: 63 AGDEESYEVFKELFDAVINEKHKGFGPNDSQPAPDLDASKLVGGQFDEKYVKSCRIRTGR 122 Query: 169 SIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFD 228 IRGL PP+CTR ERREVERV+ AL+GL GDL+G YY LS+MT ++ QLI DHFLF Sbjct: 123 GIRGLCYPPSCTRGERREVERVITTALAGLSGDLSGTYYPLSKMTPEQENQLIADHFLFQ 182 Query: 229 KPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFERFCR 288 KP L+ + RDWPDARGIWHNNEK+FLIW+NEEDH RVISM+KGGN+K VFERF R Sbjct: 183 KPTGHLMVNSASVRDWPDARGIWHNNEKTFLIWINEEDHMRVISMQKGGNVKAVFERFGR 242 Query: 289 GLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDSRFPKILENL 348 GL + +++ G E+MWN+RLGY+ CPSNLGTGLRA VH++L LSK +F I+ L Sbjct: 243 GLNAIAEQMKKNGREYMWNQRLGYLCACPSNLGTGLRASVHVQLHQLSKHPKFEDIVVAL 302 Query: 349 RLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLERGQDIRI 408 +LQKRGTGG TAA V+DISN RL KSE E VQL+IDGV LID E+ LE G+ I Sbjct: 303 QLQKRGTGGEHTAAVDDVYDISNAARLKKSEREFVQLLIDGVKKLIDMEQALEAGKSIDD 362 Query: 409 PTP 411 P Sbjct: 363 LIP 365 >4BG4-B nrPDB Length = 356 Score = 518 bits (1335), Expect = e-147, Method: Composition-based stats. Identities = 145/358 (40%), Positives = 211/358 (58%), Gaps = 15/358 (4%) Query: 48 PPSAEYPDLRKHNNC---MASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKT 104 A + L +C + +LT V+ +L DK T G TL IQ+GV+N Sbjct: 9 KLEAGFKKLEAATDCRSLLKKYLTKDVFDKLKDKKTSLGATLLDVIQSGVEN----LDSG 64 Query: 105 VGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDL-DASKIRSGYFDERYVLSSR 163 VG+ A D E Y +FA LFDP+I++ H G+ D D + + + ++V+S+R Sbjct: 65 VGIYAPDAEAYTLFAPLFDPIIEDYHVGFKQTDKHPNKDFGDVNSFVNVDPEGKFVISTR 124 Query: 164 VRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDD 223 VR GRS++G P T ++ +E+E V LS L+G+L G YY L+ M++ QQ+LIDD Sbjct: 125 VRCGRSMQGYPFNPCLTESQYKEMEAKVSSTLSSLEGELKGTYYPLTGMSKEVQQKLIDD 184 Query: 224 HFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVF 283 HFLF K L AA R WP RGI+HN+ K+FL+WVNEEDH R+ISM+ GG++ +VF Sbjct: 185 HFLF-KEGDRFLQAANACRYWPAGRGIYHNDNKTFLVWVNEEDHLRIISMQMGGDLGQVF 243 Query: 284 ERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKD-SRFP 342 R + E+E+ I F ++RLG++ CP+NLGT +RA VHIKLP L+ + + Sbjct: 244 RRLTSAVNEIEKRI-----PFSHHDRLGFLTFCPTNLGTTVRASVHIKLPKLAANREKLE 298 Query: 343 KILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRL 400 ++ LQ RGT G T A GG++DISN R+G +E + V+ + DG+ LI E+ + Sbjct: 299 EVAGKYNLQVRGTRGEHTEAEGGIYDISNKRRMGLTEFQAVKEMQDGILELIKIEKEM 356 >5ZHQ-A nrPDB Length = 357 Score = 515 bits (1326), Expect = e-146, Method: Composition-based stats. Identities = 143/359 (39%), Positives = 210/359 (58%), Gaps = 15/359 (4%) Query: 48 PPSAEYPDLRKHNNC---MASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKT 104 + L +C + +LT +V+ +L K T G TL IQ+GV+N Sbjct: 9 KLEEGFKKLEAATDCKSLLKKYLTKSVFDQLKGKKTSLGATLLDVIQSGVEN----LDSG 64 Query: 105 VGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDL-DASKIRSGYFDERYVLSSR 163 VG+ A D E Y +FA LFDP+I++ H G+ D D ++ + D ++V+S+R Sbjct: 65 VGVYAPDAEAYTLFAPLFDPIIEDYHKGFKQTDKHPNKDFGDVNQFVNVDPDGKFVISTR 124 Query: 164 VRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDD 223 VR GRS+ G P T A+ +E+E V LS L+G+L G YY L+ MT+ QQ+LIDD Sbjct: 125 VRCGRSMEGYPFNPCLTEAQYKEMESKVSSTLSNLEGELKGTYYPLTGMTKDVQQKLIDD 184 Query: 224 HFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVF 283 HFLF K L AA R WP RGI+HN+ K+FL+W +EEDH R+ISM+ GG++ +V+ Sbjct: 185 HFLF-KEGDRFLQAANACRYWPTGRGIYHNDNKTFLVWCDEEDHLRIISMQMGGDLGQVY 243 Query: 284 ERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKD-SRFP 342 R + E+E+ + F ++RLG++ CP+NLGT +RA VHIKLP L+ + + Sbjct: 244 RRLVSAVNEIEKRV-----PFSHHDRLGFLTFCPTNLGTTVRASVHIKLPKLAANREKLE 298 Query: 343 KILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLE 401 ++ LQ RGT G T A GGV+DISN R+G +E + V+ + DG+ LI E+ ++ Sbjct: 299 EVAGKYSLQVRGTRGEHTEAEGGVYDISNKRRMGLTEFQAVKEMQDGILELIKIEKEMQ 357 >5U8E-A nrPDB Length = 384 Score = 510 bits (1313), Expect = e-145, Method: Composition-based stats. Identities = 144/363 (39%), Positives = 207/363 (57%), Gaps = 15/363 (4%) Query: 42 ERRRLYPPSAEYPDLRKHNNC---MASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPG 98 ++ L A + L+ +C + +L V+ + T G TL CIQ+GV+N Sbjct: 30 DQATLDKLEAGFKKLQDATDCKSLLKKYLNREVFDQCKSLKTALGATLLDCIQSGVEN-- 87 Query: 99 HPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDL-DASKIRSGYFDER 157 VG+ A D E Y +FA +F+P+I++ H G+ P TD D + I + + Sbjct: 88 --LDSGVGIYAPDAEAYTLFAPIFNPIIEDYHEGFKPTDKHPPTDFGDINTIVNVDPSGK 145 Query: 158 YVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQ 217 YV+S+ VR GRS++G P T A +E+E V +G+L G+YY L+ M +A Q Sbjct: 146 YVVSTHVRCGRSLKGYPFNPCLTEANYKEMEDKVSAIFGTFEGELKGKYYPLTGMDKATQ 205 Query: 218 QQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGG 277 QQLIDDHFLF K L AA R WP RGI+HN+ K+FL+WVNEEDH R+ISM+KGG Sbjct: 206 QQLIDDHFLF-KEGDRFLQAANACRYWPTGRGIYHNDAKTFLVWVNEEDHLRIISMQKGG 264 Query: 278 NMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSK 337 ++K +F+R + +E + F ++RLG++ CP+NLGT +RA VHI LP L+K Sbjct: 265 DLKTIFQRLVNAVNTIESKL-----PFSRDDRLGFLTFCPTNLGTTIRASVHIALPKLAK 319 Query: 338 DSR-FPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDC 396 D + I LQ RGT G T + GGV+DISN R+G +E + V+ + DG+ +I Sbjct: 320 DKKQLEAIAAKFNLQVRGTRGEHTESEGGVYDISNKRRMGLTEYQAVKEMQDGILEMIKM 379 Query: 397 ERR 399 E Sbjct: 380 EEA 382 >4GVZ-A nrPDB Length = 357 Score = 504 bits (1297), Expect = e-143, Method: Composition-based stats. Identities = 141/363 (38%), Positives = 208/363 (57%), Gaps = 15/363 (4%) Query: 42 ERRRLYPPSAEYPDLRKHNNC---MASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPG 98 ++ L A + L++ ++C + HLT V+ + +K T G TL IQ+GV+N Sbjct: 3 DQATLDKLEAGFKKLQEASDCKSLLKKHLTKDVFDSIKNKKTGMGATLLDVIQSGVEN-- 60 Query: 99 HPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTD-LDASKIRSGYFDER 157 VG+ A D E+Y F LFDP+I + H G+ D + + + Sbjct: 61 --LDSGVGIYAPDAESYRTFGPLFDPIIDDYHGGFKLTDKHPPKQWGDINTLVGLDPAGQ 118 Query: 158 YVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQ 217 +++S+RVR GRS++G P T + +E+E V LS ++ +L G YY L+ M++A Q Sbjct: 119 FIISTRVRCGRSLQGYPFNPCLTAEQYKEMEEKVSSTLSSMEDELKGTYYPLTGMSKATQ 178 Query: 218 QQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGG 277 QQLIDDHFLF K L A R WP RGI+HN+ K+FL+WVNEEDH R+ISM+KGG Sbjct: 179 QQLIDDHFLF-KEGDRFLQTANACRYWPTGRGIFHNDAKTFLVWVNEEDHLRIISMQKGG 237 Query: 278 NMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSK 337 ++K V++R + +E + F ++R G++ CP+NLGT +RA VHI+LP L+K Sbjct: 238 DLKTVYKRLVTAVDNIESKL-----PFSHDDRFGFLTFCPTNLGTTMRASVHIQLPKLAK 292 Query: 338 DSR-FPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDC 396 D + I LQ RGT G T + GGV+DISN RLG +E + V+ + DG+ +I Sbjct: 293 DRKVLEDIASKFNLQVRGTRGEHTESEGGVYDISNKRRLGLTEYQAVREMQDGILEMIKM 352 Query: 397 ERR 399 E+ Sbjct: 353 EKA 355 >2J1Q-A nrPDB Length = 357 Score = 501 bits (1290), Expect = e-142, Method: Composition-based stats. Identities = 145/356 (40%), Positives = 206/356 (57%), Gaps = 15/356 (4%) Query: 48 PPSAEYPDLRKHNNC---MASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKT 104 A + L+ ++C + +LT V+ +L K T G TL IQ+GV+N Sbjct: 9 KLEAAFAKLQNASDCHSLLKKYLTKEVFDQLKGKQTKMGATLMDVIQSGVEN----LDSG 64 Query: 105 VGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTD-LDASKIRSGYFDERYVLSSR 163 +G+ A D E+Y +FA L DP+I++ H G+ P + D D + D++YV+S+R Sbjct: 65 IGVYAPDAESYTLFAALLDPIIEDYHKGFKPSDKQPPKDSGDLNTFIDVDPDKKYVISTR 124 Query: 164 VRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDD 223 VR GRS+ G P + + E+E V L + G+L G+YY L+ MT+ Q+QLIDD Sbjct: 125 VRCGRSLEGYPFNPCLKKQQYEEMESRVKGQLESMSGELRGKYYPLTGMTKETQKQLIDD 184 Query: 224 HFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVF 283 HFLF K L AA + WP RGI+HN+ K+FL+WVNEEDH R+ISM+KGGN+K VF Sbjct: 185 HFLF-KEGDRFLQAAHACKFWPTGRGIYHNDAKTFLVWVNEEDHLRIISMQKGGNLKEVF 243 Query: 284 ERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKD-SRFP 342 R + +E ++ F ++RLG++ CP+NLGT +RA VHIKLP L D + Sbjct: 244 GRLVTAVGVIEEKVK-----FSRDDRLGFLTFCPTNLGTTIRASVHIKLPKLGADRKKLE 298 Query: 343 KILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCER 398 ++ LQ RGT G + + GV+DISN RLG SE E V+ + DG+ LI E Sbjct: 299 EVAAKYNLQVRGTAGEHSDSPDGVYDISNKRRLGLSEYEAVKEMQDGILELIKAEE 354 >4RF9-A nrPDB Length = 718 Score = 500 bits (1288), Expect = e-142, Method: Composition-based stats. Identities = 159/374 (42%), Positives = 226/374 (60%), Gaps = 21/374 (5%) Query: 36 PVRAASERRRLYPPSAEYPDLRKHNNC-----MASHLTPAVYARLCDKTTPTGWTLDQCI 90 P A E + +PD C + +LTP V+ L +K T G TL CI Sbjct: 2 PHMADPETAAKFKSKNAFPDPLNDPKCNPKSLVKKYLTPKVFESLKNKKTKLGITLWDCI 61 Query: 91 QTGVDNPGHPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIR 150 +GV N VG+ AGDEE+Y +F LFD +I++ H+ Y T H +D++ + ++ Sbjct: 62 NSGVVN----LDSGVGVYAGDEESYTLFGPLFDAIIEDYHSPYKLAT-GHNSDMNPAHVK 116 Query: 151 SGYFDE--RYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYR 208 + D RY+ S+R+R RS++G L P T+A R E+E+ VV L+ L GDLAG+YY Sbjct: 117 APDLDPANRYIRSTRIRVARSLKGYGLAPGVTKAHRLEIEKKVVGVLTSLTGDLAGKYYP 176 Query: 209 LSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHT 268 LS M E +QQL+DDHFLF K L AAG+ ++WP+ RGI+HNN+K+FL+W+NEEDH Sbjct: 177 LSGMDEKTRQQLVDDHFLFKK-GDRFLEAAGINKEWPEGRGIYHNNDKTFLVWLNEEDHL 235 Query: 269 RVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGV 328 R+ISMEKG ++ VF R CR + E+++ + F ++ GY+ +CPSNLGTG+RA V Sbjct: 236 RIISMEKGSDIGSVFSRLCRAVNEIDKKL-----GFQHTKKHGYLTSCPSNLGTGMRASV 290 Query: 329 HIKLPLLSKDSRFPKILENLRLQKRGTGGVDTAATG---GVFDISNLDRLGKSEVELVQL 385 H+K+P + F IL +Q RG G + +TG GV+DISN RLG SEV+ VQ Sbjct: 291 HVKIPHAKEHPDFENILTKYHIQARGIHGEHSESTGEDAGVYDISNRRRLGLSEVQCVQD 350 Query: 386 VIDGVNYLIDCERR 399 + DGV L++ E+ Sbjct: 351 MYDGVKALMELEKE 364 Score = 443 bits (1139), Expect = e-125, Method: Composition-based stats. Identities = 152/365 (41%), Positives = 228/365 (62%), Gaps = 19/365 (5%) Query: 42 ERRRLYPPSAEYPDLRKHN---NCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPG 98 E+ + + +P++ K+ + + +LTP ++ L DK T G +L CI +GV+N Sbjct: 362 EKEAIAKKRSVFPEVLKNPEVKSLLRKYLTPELFDSLKDKKTAKGISLYDCINSGVEN-- 419 Query: 99 HPFIKTVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKI--RSGYFDE 156 + G+ AGDEE Y +FA LFD ++++ H+ Y KHT+D++ K+ + + Sbjct: 420 --LDSSCGVYAGDEECYTLFAPLFDKIVEDYHSPYK-LANKHTSDMNPEKVDAPNLDPEG 476 Query: 157 RYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAE 216 Y+ S+R+R R+++G +L P TR ER ++ER VV LS L GDLAG+YY L+ M EA Sbjct: 477 TYIRSTRIRVARNVKGYALTPGLTRNERLDIERKVVGVLSSLTGDLAGQYYPLTGMDEAT 536 Query: 217 QQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKG 276 +Q+L++DHFLF K L AAG+ + WP+ RGI+HNN+K+FL+W+NEED R+ISMEKG Sbjct: 537 RQKLVNDHFLFKK-GDRFLEAAGVNKLWPEGRGIFHNNDKTFLVWINEEDQLRIISMEKG 595 Query: 277 GNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLS 336 ++ VF R CR + E+++ + F + GY+ CP+NLGTG+RA VH+K+P S Sbjct: 596 SDIGSVFGRLCRAVNEIDKQL-----GFQHTDAHGYLSGCPTNLGTGMRASVHVKIPKAS 650 Query: 337 KDSRFPKILENLRLQKRGTGGVDTAATG---GVFDISNLDRLGKSEVELVQLVIDGVNYL 393 F KI + +Q RG G + +TG GVFDISN RLG SEV+ VQ + +GV L Sbjct: 651 AHPDFQKICDEFHIQARGIHGEHSVSTGEDAGVFDISNRRRLGLSEVQCVQDMYNGVKKL 710 Query: 394 IDCER 398 ++ E+ Sbjct: 711 LEIEK 715 >4WO8-A nrPDB Length = 716 Score = 442 bits (1137), Expect = e-124, Method: Composition-based stats. Identities = 133/346 (38%), Positives = 198/346 (57%), Gaps = 17/346 (4%) Query: 60 NNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKTVGMVAGDEETYEVFA 119 +LTP + + K T G TL I+ G N +++ G+ E Y F Sbjct: 383 KCYTRKYLTPEIIKKYDGKRTTHGATLAHMIRNGAYNN-----RSICPRTGEAECYSTFI 437 Query: 120 DLFDPVIQERHNGYDPRTMKHT--TDLDASKIRSGYFDE--RYVLSSRVRTGRSIRGLSL 175 D DP+I + H G KH T D SK+ G D ++++S+RVR GRS+ G Sbjct: 438 DYLDPLICDYH-GVKDSAFKHPAPTFGDLSKLPFGDLDPTGKFIVSTRVRVGRSVEGFLF 496 Query: 176 PPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPVSPLL 235 P ++ +R ++E+V+ AL GL G+ AG YY L++M E +++QL++DHFLF K P+L Sbjct: 497 PTIMSKTDRIKLEQVISGALKGLTGEHAGTYYPLTDMKEEDRKQLVEDHFLF-KNDDPVL 555 Query: 236 TAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFERFCRGLKEVER 295 AG RDWP RGI+HNN K+FL+WV EEDH R+ISM++GGN+ V++R G+ + + Sbjct: 556 RDAGGYRDWPVGRGIFHNNSKTFLVWVCEEDHMRIISMQQGGNLAAVYKRLIEGINAIGK 615 Query: 296 LIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDS-RFPKILENLRLQKRG 354 ++ F +++ GYI CPSNLGT +RA V +K+P LS + +I LQ RG Sbjct: 616 SMK-----FAHSDKYGYITCCPSNLGTSMRASVLLKIPKLSSQPKKLDEICAKYMLQARG 670 Query: 355 TGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRL 400 G T + G +DISN RLG +E++ + +GV +I+ E+ L Sbjct: 671 LYGEHTESPDGTYDISNKRRLGLTELQAAHEMAEGVAKMIEIEKGL 716 Score = 378 bits (971), Expect = e-105, Method: Composition-based stats. Identities = 131/351 (37%), Positives = 195/351 (55%), Gaps = 15/351 (4%) Query: 55 DLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKTVGMVAGDEET 114 D R H+ +LT + + T G TL QC+ T NPG ++ D Sbjct: 16 DERNHS-LTKKYLTDDIVKKYQATKTSLGGTLAQCVNTNAYNPGALLPRSC-----DLNA 69 Query: 115 YEVFADLFDPVIQERHNGYDPRTMKHTTDL-DASKIRSGYFD--ERYVLSSRVRTGRSIR 171 YE F D FD VI + H D + ++ D + + V+S+RVR GR++ Sbjct: 70 YETFRDFFDAVIADYHKVPDGKIQHPKSNFGDLKSLSFTDLNTYGNLVVSTRVRLGRTVE 129 Query: 172 GLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPV 231 G P T+ R E+E + AL L G+ G YY L+ M+E ++ +L++DHFLF + Sbjct: 130 GFGFGPTLTKETRIELENKISTALHNLSGEYEGTYYPLTGMSEEDRIKLVNDHFLF-RND 188 Query: 232 SPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFERFCRGLK 291 +L AG DWP RGI+ N +K+FL+W+NEEDH RVISM+KGG + V++R ++ Sbjct: 189 DNVLRDAGGYIDWPTGRGIFINKQKNFLVWINEEDHIRVISMQKGGGLTAVYKRLADAIQ 248 Query: 292 EVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDSRFPKILENLRLQ 351 E+ + ++ F +N+RLG+I CPSNLGT LRA VH K+P+L+ F +I E +Q Sbjct: 249 ELSKSLK-----FAFNDRLGFITFCPSNLGTTLRASVHAKIPMLASLPNFKEICEKHGIQ 303 Query: 352 KRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLER 402 RGT G T + GG++D+SN RLG +E++ V + GV L++ E L+ Sbjct: 304 PRGTHGEHTESVGGIYDLSNKRRLGLTELDAVTEMHSGVRALLELEVMLQE 354 >6FH2-A nrPDB Length = 366 Score = 262 bits (670), Expect = 2e-70, Method: Composition-based stats. Identities = 81/251 (32%), Positives = 122/251 (48%), Gaps = 21/251 (8%) Query: 154 FDERYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRY--YRLSE 211 + VLSSR+R R+I P + E +++ + A AGR+ ++SE Sbjct: 23 PNSDIVLSSRIRLARNIVDFRFPTLFSSEEAKQIVALFERAFVHRPYGEAGRFELLKMSE 82 Query: 212 MTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVI 271 + E++ L++ H +SP L A D P + NE+ I +NEEDH R+ Sbjct: 83 LQPIEKRVLVEKHL-----ISPHL-----AEDSPFGACLLSENEE-ISIMINEEDHIRIQ 131 Query: 272 SMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIK 331 + G + E E++ I E + ++ERLGY+ +CP+N+GTGLRA V + Sbjct: 132 CLFPGLQLAEALE----AASELDDWI-EGHVNYAFDERLGYLTSCPTNVGTGLRASVMMH 186 Query: 332 LPLLSKDSRFPKI---LENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVID 388 LP L + +I + L L RGT G + A G +F ISN LGKSE ++V + Sbjct: 187 LPALVLTQQINRIIPAINQLGLVVRGTYGEGSEALGNIFQISNQITLGKSEEDIVADLHT 246 Query: 389 GVNYLIDCERR 399 V LI ER Sbjct: 247 IVEQLIAQERA 257 >6D1P-A nrPDB Length = 814 Score = 33.0 bits (74), Expect = 0.26, Method: Composition-based stats. Identities = 21/101 (20%), Positives = 37/101 (36%), Gaps = 8/101 (7%) Query: 290 LKEVERLIQERGWEFMWNERLGYILTCPSNL---GTGLRAGVHIKLPLLSKDSRFPKILE 346 L E+ +W+ + TC + L G LR H + + P L Sbjct: 260 LTEISSYQISLKRPQLWSPHSPALYTCVAELIDNGDTLRTTQHFGFRHFRFEEKGPFYLN 319 Query: 347 NLRLQKRGTG-GVDTAATGGVFDISNLDRLGKSEVELVQLV 386 RL RGT D A G + + ++E++ ++ + Sbjct: 320 GERLLLRGTHRHEDHAGVGAAL----TEEMMRTEMQQIKEM 356 >1NYT-A nrPDB Length = 271 Score = 30.7 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 20/57 (35%), Positives = 25/57 (43%), Gaps = 2/57 (3%) Query: 5 FSRLLSARPGLRLLALAGAGSLAAGFLLRPEPV-RAASERRRLYPPSAEYPDLRKHN 60 RL RPGLR+L L GAG + G LL + A + R + E L H Sbjct: 110 LERLSFIRPGLRIL-LIGAGGASRGVLLPLLSLDCAVTITNRTVSRAEELAKLFAHT 165 >5B6K-A nrPDB Length = 366 Score = 30.7 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 30/61 (49%), Gaps = 1/61 (1%) Query: 338 DSRFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCE 397 + +FP++ + K GTG D A V + LG ++L + + D ++ +++ E Sbjct: 304 NEQFPELKGKIPAGKPGTGNPD-DALTPVDNSKTKKLLGFEFIDLKKDLYDTISQILEAE 362 Query: 398 R 398 + Sbjct: 363 K 363 >3SL2-A nrPDB Length = 177 Score = 30.0 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 32/74 (43%), Gaps = 12/74 (16%) Query: 238 AGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGG------NMKRVFERFCRGLK 291 + + P+ + +F I VNEE+ IS++ G ++++VF+RF R K Sbjct: 53 SNALKYSPEGGHV------TFSIDVNEEEELLYISVKDEGIGIPKKDVEKVFDRFYRVDK 106 Query: 292 EVERLIQERGWEFM 305 R + G Sbjct: 107 ARTRKLGGTGLGLA 120 >3U1H-A nrPDB Length = 390 Score = 30.0 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 12/48 (25%), Positives = 23/48 (47%), Gaps = 5/48 (10%) Query: 181 RAERREVERVVVDAL--SGLKGDLA---GRYYRLSEMTEAEQQQLIDD 223 E + +E+ V L D+A G+Y +EMT+ + ++D+ Sbjct: 332 EEEAKAIEKAVEKVLAEGYRTADIAKPGGKYVSTTEMTDEVKAAVVDE 379 >5OGQ-A nrPDB Length = 254 Score = 29.6 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 27/92 (29%), Gaps = 14/92 (15%) Query: 34 PEPVRAASERRRLYPP--SAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQ 91 P P + YPP S Y R C + TP + K++ Sbjct: 105 PFPKC-EHHTKGKYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYN--------- 154 Query: 92 TGVDNPGHPFIKTVGMVAGDEETYEVFADLFD 123 V N K + E + V+ D + Sbjct: 155 --VKNDEKAIQKEIMKYGPVEAGFTVYEDFLN 184 >4I05-A nrPDB Length = 285 Score = 29.6 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 27/92 (29%), Gaps = 14/92 (15%) Query: 34 PEPVRAASERRRLYPP--SAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQ 91 P P + YPP S Y R C + TP + K++ Sbjct: 136 PFPKC-EHHTKGKYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYN--------- 185 Query: 92 TGVDNPGHPFIKTVGMVAGDEETYEVFADLFD 123 V N K + E + V+ D + Sbjct: 186 --VKNDEKAIQKEIMKYGPVEAGFTVYEDFLN 215 >4I04-A nrPDB Length = 323 Score = 29.6 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 27/92 (29%), Gaps = 14/92 (15%) Query: 34 PEPVRAASERRRLYPP--SAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQ 91 P P + YPP S Y R C + TP + K++ Sbjct: 174 PFPKC-EHHTKGKYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYN--------- 223 Query: 92 TGVDNPGHPFIKTVGMVAGDEETYEVFADLFD 123 V N K + E + V+ D + Sbjct: 224 --VKNDEKAIQKEIMKYGPVEAGFTVYEDFLN 253 >3IO3-A nrPDB Length = 348 Score = 29.6 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 25/49 (51%), Gaps = 4/49 (8%) Query: 270 VISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPS 318 ++SM GG + +FE+ L EV++ + E +F E +I C S Sbjct: 196 MLSMMGGGQQQDIFEK----LNEVQKNVSEVNEQFTNPELTTFICVCIS 240 >5LOL-A nrPDB Length = 215 Score = 29.2 bits (64), Expect = 3.6, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 30/90 (33%), Gaps = 11/90 (12%) Query: 137 TMKHTTDLDAS---KIRSGYFDERYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVD 193 + K LD S K+ D ++V S V G P T E V + Sbjct: 47 SDKPQWFLDISPEGKVPVVKLDGKWVADSDVIVGLLEEKYPEPSLKTPPEFASVGSKIFG 106 Query: 194 ALSGLKGDLAGRYYRLSEMTEAEQQQLIDD 223 A + + + + ++ L+D+ Sbjct: 107 AFV--------TFLKSKDANDGSEKALVDE 128 >1GZU-A nrPDB Length = 290 Score = 28.8 bits (63), Expect = 4.0, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 31/80 (38%), Gaps = 3/80 (3%) Query: 332 LPLLSKDSRFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVN 391 +P L K +I+ N L G D +++ S++ +S + +V I Sbjct: 176 VPNLWKSEDITQIVANYGLICVTRAGNDAQKF--IYE-SDVLWKHRSNIHVVNEWIANDI 232 Query: 392 YLIDCERRLERGQDIRIPTP 411 R L RGQ IR P Sbjct: 233 SSTKIRRALRRGQSIRYLVP 252 >1A8Y-A nrPDB Length = 367 Score = 28.8 bits (63), Expect = 5.1, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 34/98 (34%), Gaps = 24/98 (24%) Query: 340 RFPKILENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVE------------------ 381 +++ L Q GV D + +LG +E + Sbjct: 52 EMEELILELAAQVLEDKGVGFGLVDSEKDAAVAKKLGLTEEDSIYVFKEDEVIEYDGEFS 111 Query: 382 ---LVQLVIDGVN---YLIDCERRLERGQDIRIPTPVI 413 LV+ ++D + LI+ ER L+ ++I +I Sbjct: 112 ADTLVEFLLDVLEDPVELIEGERELQAFENIEDEIKLI 149 >2PSB-A nrPDB Length = 320 Score = 28.0 bits (61), Expect = 8.6, Method: Composition-based stats. Identities = 21/114 (18%), Positives = 38/114 (33%), Gaps = 11/114 (9%) Query: 104 TVGMVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDERYVLSSR 163 TVG V E + ++ FD + H+G+ P K A + FD + Sbjct: 78 TVGPVRSAREYFVTLSNGFDSIF--VHHGWSPGAKKQLESGAADYMNGLDFDGSLFWRA- 134 Query: 164 VRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQ 217 S PP + +++ LK + ++ S+ A + Sbjct: 135 --------DFSKPPHNSYTSYDYIKKAAEQKGYKLKQETNPLLFQTSDAKPANE 180 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.314 0.141 0.391 Lambda K H 0.267 0.0431 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,269,667 Number of Sequences: 36641 Number of extensions: 748185 Number of successful extensions: 1974 Number of sequences better than 10.0: 32 Number of HSP's better than 10.0 without gapping: 39 Number of HSP's successfully gapped in prelim test: 23 Number of HSP's that attempted gapping in prelim test: 1809 Number of HSP's gapped (non-prelim): 68 length of query: 417 length of database: 10,336,785 effective HSP length: 100 effective length of query: 317 effective length of database: 6,672,685 effective search space: 2115241145 effective search space used: 2115241145 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 61 (28.0 bits)