BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P12385 (437 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4CRN-X nrPDB 887 0.0 5LZU-ii nrPDB 619 e-177 3E20-C nrPDB 579 e-165 4CRM-X nrPDB 573 e-164 2HST-A nrPDB 223 2e-58 2LLX-A nrPDB 218 3e-57 4AF1-A nrPDB 190 8e-49 2KTV-A nrPDB 184 6e-47 3AGK-A nrPDB 145 3e-35 3IR9-A nrPDB 59 4e-09 3MCA-B nrPDB 47 1e-05 3J15-A nrPDB 45 8e-05 3WXM-B nrPDB 43 3e-04 2QI2-A nrPDB 40 0.002 3OBW-A nrPDB 33 0.31 2VGN-A nrPDB 32 0.37 3IEB-A nrPDB 32 0.41 5OLJ-A nrPDB 31 0.83 5DCV-A nrPDB 31 1.3 5EVI-D nrPDB 30 1.4 4V6W-Cc nrPDB 29 3.4 3JS5-A nrPDB 28 7.2 >4CRN-X nrPDB Length = 437 Score = 887 bits (2291), Expect = 0.0, Method: Compositional matrix adjust. Identities = 435/437 (99%), Positives = 436/437 (99%) Query: 1 MDNEVEKNIEIWKVKKLVQSLEKARGNGTSMISLVIPPKGQIPLYQKMLTDEYGTASNIK 60 MDNEVEKNIEIWKVKKLVQSLEKARGNGTSMISLVIPPKG IPLYQKMLTDEYGTASNIK Sbjct: 1 MDNEVEKNIEIWKVKKLVQSLEKARGNGTSMISLVIPPKGLIPLYQKMLTDEYGTASNIK 60 Query: 61 SRVNRLSVLSAITSTQQKLKLYNTLPKNGLVLYCGDIITEDGKEKKVTFDIEPYKPINTS 120 SRVNRLSVLSAITSTQQKLKLYNTLPKNGLVLYCGDIITEDGKEKKVTFDIEPYKPINTS Sbjct: 61 SRVNRLSVLSAITSTQQKLKLYNTLPKNGLVLYCGDIITEDGKEKKVTFDIEPYKPINTS 120 Query: 121 LYLCDNKFHTEVLSELLQADDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRG 180 LYLCDNKFHTEVLSELLQADDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRG Sbjct: 121 LYLCDNKFHTEVLSELLQADDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRG 180 Query: 181 GQSALRFARLREEKRHNYVRKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFD 240 GQSALRFARLREEKRHNYVRKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFD Sbjct: 181 GQSALRFARLREEKRHNYVRKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFD 240 Query: 241 PRLACKVISIVDVSYGGENGFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFCY 300 PRLACKVISIVDVSYGGENGFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFC+ Sbjct: 241 PRLACKVISIVDVSYGGENGFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFCF 300 Query: 301 GIDDTLKALDLGAVEKLIVFENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQE 360 GIDDTLKALDLGAVEKLIVFENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQE Sbjct: 301 GIDDTLKALDLGAVEKLIVFENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQE 360 Query: 361 MDVVSEEPLIEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVNFEQLVDE 420 MDVVSEEPLIEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVNFEQLVDE Sbjct: 361 MDVVSEEPLIEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVNFEQLVDE 420 Query: 421 SEDEYYDEDEGSDYDFI 437 SEDEYYDEDEGSDYDFI Sbjct: 421 SEDEYYDEDEGSDYDFI 437 >5LZU-ii nrPDB Length = 459 Score = 619 bits (1595), Expect = e-177, Method: Compositional matrix adjust. Identities = 292/428 (68%), Positives = 354/428 (82%), Gaps = 3/428 (0%) Query: 6 EKNIEIWKVKKLVQSLEKARGNGTSMISLVIPPKGQIPLYQKMLTDEYGTASNIKSRVNR 65 ++N+EIWK+KKL++SLE ARGNGTSMISL+IPPK QI KML DE+GTASNIKSRVNR Sbjct: 31 DRNVEIWKIKKLIKSLEAARGNGTSMISLIIPPKDQISRVAKMLADEFGTASNIKSRVNR 90 Query: 66 LSVLSAITSTQQKLKLYNTLPKNGLVLYCGDIITEDGKEKKVTFDIEPYKPINTSLYLCD 125 LSVL AITS QQ+LKLYN +P NGLV+YCG I+TE+GKEKKV D EP+KPINTSLYLCD Sbjct: 91 LSVLGAITSVQQRLKLYNKVPPNGLVVYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCD 150 Query: 126 NKFHTEVLSELLQADDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRGGQSAL 185 NKFHTE L+ LL D KFGFIV+DG G LFG++ GNTR VLHKFTVDLPKKHGRGGQSAL Sbjct: 151 NKFHTEALTALLSDDSKFGFIVIDGSGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSAL 210 Query: 186 RFARLREEKRHNYVRKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFDPRLAC 245 RFARLR EKRHNYVRKVAE AVQ FI+ DKVNV GL+LAGSADFKT+L++S++FD RL Sbjct: 211 RFARLRMEKRHNYVRKVAETAVQLFISGDKVNVAGLVLAGSADFKTELSQSDMFDQRLQS 270 Query: 246 KVISIVDVSYGGENGFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDT 305 KV+ +VD+SYGGENGFNQAIELS E L+NVK++QEKKL+ YFDEISQDTGK+C+G++DT Sbjct: 271 KVLKLVDISYGGENGFNQAIELSTEVLSNVKFIQEKKLIGRYFDEISQDTGKYCFGVEDT 330 Query: 306 LKALDLGAVEKLIVFENLETIRYTF--KDAEDNEVIKFAEPEAKDKSFAIDKATGQEMDV 363 LKAL++GAVE LIV+ENL+ +RY + E+ +++ + KDKS DK TGQE ++ Sbjct: 331 LKALEMGAVEILIVYENLDIMRYVLHCQGTEEEKILYLTPEQEKDKSHFTDKETGQEHEL 390 Query: 364 VSEEPLIEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVNFEQL-VDESE 422 + PL+EW A NYK FGATLE +TDKS EG+QFV GFGGIG +LRY+V+F+ + + Sbjct: 391 IESMPLLEWFANNYKKFGATLEIVTDKSQEGSQFVKGFGGIGGILRYRVDFQGMEYQGGD 450 Query: 423 DEYYDEDE 430 DE++D D+ Sbjct: 451 DEFFDLDD 458 >3E20-C nrPDB Length = 441 Score = 579 bits (1492), Expect = e-165, Method: Compositional matrix adjust. Identities = 274/428 (64%), Positives = 344/428 (80%), Gaps = 4/428 (0%) Query: 6 EKNIEIWKVKKLVQSLEKARGNGTSMISLVIPPKGQIPLYQKMLTDEYGTASNIKSRVNR 65 EK IEIWK+++LV+ L GNGTSMI+L+IPP QI Y ML +EYGTASNIKSRVNR Sbjct: 14 EKAIEIWKIRRLVKQLINCHGNGTSMITLIIPPGEQISRYSNMLAEEYGTASNIKSRVNR 73 Query: 66 LSVLSAITSTQQKLKLYNTLPKNGLVLYCGDIITEDGKEKKVTFDIEPYKPINTSLYLCD 125 LSVLSAITST+++LKLYN +P NGLV+YCG++I E K +K+ D EP+KPINTS YLCD Sbjct: 74 LSVLSAITSTRERLKLYNKVPDNGLVIYCGEVIMEGNKTRKLNIDFEPFKPINTSQYLCD 133 Query: 126 NKFHTEVLSELLQADDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRGGQSAL 185 NKFHTE L+ELL++D +FGFIVMDG TL+G VSG+ R VL +FTVDLPKKHGRGGQSAL Sbjct: 134 NKFHTEALAELLESDQRFGFIVMDGHQTLYGVVSGSAREVLQRFTVDLPKKHGRGGQSAL 193 Query: 186 RFARLREEKRHNYVRKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFDPRLAC 245 RFARLR+EKRHNYVRKVAE AVQ+FIT+DK NV G++LAGSADFKT+L +S+LFD RL Sbjct: 194 RFARLRDEKRHNYVRKVAEGAVQHFITDDKPNVAGIVLAGSADFKTELGQSDLFDQRLQS 253 Query: 246 KVISIVDVSYGGENGFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDT 305 ++I VDVSYGG+ GFNQAIEL+A+ L+NVKYVQEKKL++ +FDEIS D+GK+C+G+ DT Sbjct: 254 RIIKTVDVSYGGDAGFNQAIELAADTLSNVKYVQEKKLIQRFFDEISLDSGKYCFGVVDT 313 Query: 306 LKALDLGAVEKLIVFENLETIRYTFKDAEDNEVIKFAEPEAKDK----SFAIDKATGQEM 361 + AL GAVE L+ F +L+ IRY FK++E N VI + E ++K SF +DK TG EM Sbjct: 314 MNALQEGAVETLLCFADLDMIRYEFKNSEGNPVITYMTKEQEEKDSTNSFLLDKDTGAEM 373 Query: 362 DVVSEEPLIEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVNFEQLVDES 421 ++VS L EWLA +YK++GA LEF++D+S EG QFV GFGGIGA++RY+++ L ES Sbjct: 374 ELVSSMLLSEWLAEHYKDYGANLEFVSDRSQEGMQFVKGFGGIGAVMRYQLDLSMLDPES 433 Query: 422 EDEYYDED 429 ++ Y D D Sbjct: 434 DEFYSDSD 441 >4CRM-X nrPDB Length = 282 Score = 573 bits (1477), Expect = e-164, Method: Compositional matrix adjust. Identities = 282/282 (100%), Positives = 282/282 (100%) Query: 140 DDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRGGQSALRFARLREEKRHNYV 199 DDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRGGQSALRFARLREEKRHNYV Sbjct: 1 DDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRGGQSALRFARLREEKRHNYV 60 Query: 200 RKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFDPRLACKVISIVDVSYGGEN 259 RKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFDPRLACKVISIVDVSYGGEN Sbjct: 61 RKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFDPRLACKVISIVDVSYGGEN 120 Query: 260 GFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTLKALDLGAVEKLIV 319 GFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTLKALDLGAVEKLIV Sbjct: 121 GFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTLKALDLGAVEKLIV 180 Query: 320 FENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQEMDVVSEEPLIEWLAANYKN 379 FENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQEMDVVSEEPLIEWLAANYKN Sbjct: 181 FENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQEMDVVSEEPLIEWLAANYKN 240 Query: 380 FGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVNFEQLVDES 421 FGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVNFEQLVDES Sbjct: 241 FGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVNFEQLVDES 282 >2HST-A nrPDB Length = 143 Score = 223 bits (567), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 105/136 (77%), Positives = 118/136 (86%) Query: 137 LQADDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRGGQSALRFARLREEKRH 196 L D KFGFIV+DG G LFG++ GNTR VLHKFTVDLPKKHGRGGQSALRFARLR EKRH Sbjct: 1 LSDDSKFGFIVIDGSGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRH 60 Query: 197 NYVRKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFDPRLACKVISIVDVSYG 256 NYVRKVAE AVQ FI+ DKVNV GL+LAGSADFKT+L++S++FD RL KV+ +VD+SYG Sbjct: 61 NYVRKVAETAVQLFISGDKVNVAGLVLAGSADFKTELSQSDMFDQRLQSKVLKLVDISYG 120 Query: 257 GENGFNQAIELSAEAL 272 GENGFNQAIELS E L Sbjct: 121 GENGFNQAIELSTEVL 136 >2LLX-A nrPDB Length = 150 Score = 218 bits (556), Expect = 3e-57, Method: Compositional matrix adjust. Identities = 100/133 (75%), Positives = 115/133 (86%) Query: 6 EKNIEIWKVKKLVQSLEKARGNGTSMISLVIPPKGQIPLYQKMLTDEYGTASNIKSRVNR 65 ++N+EIWK+KKL++SLE ARGNGTSMISL+IPPK QI KML DE+GTASNIKSRVNR Sbjct: 9 DRNVEIWKIKKLIKSLEAARGNGTSMISLIIPPKDQISRVAKMLADEFGTASNIKSRVNR 68 Query: 66 LSVLSAITSTQQKLKLYNTLPKNGLVLYCGDIITEDGKEKKVTFDIEPYKPINTSLYLCD 125 LSVL AITS QQ+LKLYN +P NGLV+YCG I+TE+GKEKKV D EP+KPINTSLYLCD Sbjct: 69 LSVLGAITSVQQRLKLYNKVPPNGLVVYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCD 128 Query: 126 NKFHTEVLSELLQ 138 NKFHTE L+ LL Sbjct: 129 NKFHTEALTALLS 141 >4AF1-A nrPDB Length = 416 Score = 190 bits (483), Expect = 8e-49, Method: Compositional matrix adjust. Identities = 127/406 (31%), Positives = 213/406 (52%), Gaps = 15/406 (3%) Query: 12 WKVKKLVQSLEKARGNGTSMISLVIPPKGQIPLYQKMLTDEYGTASNIKSRVNRLSVLSA 71 ++ +K+++ L+ G+GT ++++ IPP QI +T E+ ASNIKS+ R +V A Sbjct: 15 YEFRKVIEELKDYEGSGTQLVTIYIPPDKQISDVVAHVTQEHSEASNIKSKQTRTNVQDA 74 Query: 72 ITSTQQKLKLYNTLPK-NGLVLYCGDIITEDGKEKKVTFDIE-PYKPINTSLYLCDNKFH 129 +TS + +L+ Y+T P NG+V++ G + + G+ VT +E P +PI + Y CD+ F Sbjct: 75 LTSIKDRLRYYDTFPPDNGMVVFSGAVDSGGGRTDMVTEVLESPPQPIESFRYHCDSAFL 134 Query: 130 TEVLSELLQADDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRGGQSALRFAR 189 TE L+E+L +G IV+D + + G + G + +P K +GGQSA RFAR Sbjct: 135 TEPLAEMLGDKGLYGLIVLDRRESNVGWLKGKRVQPVKSAESLVPGKQRKGGQSAQRFAR 194 Query: 190 LREEKRHNYVRKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFDPRLACKVIS 249 LR E N+ ++VA +A F+ + + G+++ G + K + + L KV+ Sbjct: 195 LRLEAIDNFYQEVAGMADDLFVPK-RHEIDGILVGGPSPTKDEFLDGDYLHHELQDKVLG 253 Query: 250 IVDVSYGGENGFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFC-YGIDDTLKA 308 DVSY E+G + ++ ALA + +K +E +F+E+ + GK YG + T + Sbjct: 254 KFDVSYTDESGLSDLVDAGQAALAEADLMDDKSDMEEFFEEL--NGGKLATYGFEQTRRN 311 Query: 309 LDLGAVEKLIVFENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAIDKAT----GQEMDVV 364 L +G+V++L+V E+L ++ D+E E E D+ + T G+E V Sbjct: 312 LIMGSVDRLLVSEDLREDVVIYECPNDHE-----EYETIDRRNTSPEHTCSDCGEEATEV 366 Query: 365 SEEPLIEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRY 410 E I+ L + G FI+ +G Q +T FGG +LRY Sbjct: 367 DREDAIDHLMSIADQRGTETHFISTDFEKGEQLLTAFGGYAGILRY 412 >2KTV-A nrPDB Length = 170 Score = 184 bits (467), Expect = 6e-47, Method: Compositional matrix adjust. Identities = 88/161 (54%), Positives = 122/161 (75%), Gaps = 3/161 (1%) Query: 273 ANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTLKALDLGAVEKLIVFENLETIRYTF-- 330 +NVK++QEKKL+ YFDEISQDTGK+C+G++DTLKAL++GAVE LIV+ENL+ +RY Sbjct: 1 SNVKFIQEKKLIGRYFDEISQDTGKYCFGVEDTLKALEMGAVEILIVYENLDIMRYVLHC 60 Query: 331 KDAEDNEVIKFAEPEAKDKSFAIDKATGQEMDVVSEEPLIEWLAANYKNFGATLEFITDK 390 + E+ +++ + KDKS DK TGQE +++ PL+EW A NYK FGATLE +TDK Sbjct: 61 QGTEEEKILYLTPEQEKDKSHFTDKETGQEHELIESMPLLEWFANNYKKFGATLEIVTDK 120 Query: 391 SSEGAQFVTGFGGIGAMLRYKVNFEQL-VDESEDEYYDEDE 430 S EG+QFV GFGGIG +LRY+V+F+ + +DE++D D+ Sbjct: 121 SQEGSQFVKGFGGIGGILRYRVDFQGMEYQGGDDEFFDLDD 161 >3AGK-A nrPDB Length = 373 Score = 145 bits (366), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 104/404 (25%), Positives = 187/404 (46%), Gaps = 51/404 (12%) Query: 13 KVKKLVQSLEKARGNGTSMISLVIPPKGQIPLYQKMLTDEYGTASNIKSRVNRLSVLSAI 72 ++ +L++ L+K T ++SL IPP + +L EY NIK + R +V A+ Sbjct: 16 ELARLLKELKKWSAPATVLLSLYIPPGRPLSDVMTLLRQEYSITDNIKLKRTRQAVKRAL 75 Query: 73 TSTQQKLKLYNTLPKNGLVLYCGDIITEDGKEKKVTFDIEPYKPINTSLYLCDNKFHTEV 132 ++ +L++ + P NGLVL+CG+ ++ E F P +PI Y D +F T+ Sbjct: 76 SAAMDRLQMLTSTPPNGLVLFCGEDMSTGKFE---CFMFSPPEPIRVFYYRTDKRFITDF 132 Query: 133 LSELLQADDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRGGQSALRFARLRE 192 L ++++ ++ G I+++ G + G VL + +P KH GGQS R+ R+ E Sbjct: 133 LEDMVEDNNAIGIIIVERDQATIGLLKGARLEVLKELEGFVPGKHKMGGQSQRRYERIIE 192 Query: 193 EKRHNYVRKVAEVAVQNFIT-NDKVNVKGLILAGSADFKTDLAKSELFDPRLACKVIS-- 249 + + +KV E A + +K +KG+I+AG K + + D RL K+++ Sbjct: 193 QMVDEFFKKVGEEASNLLVPLAEKGVLKGVIVAGPGLAKQEFVEGNYLDYRLK-KILAPE 251 Query: 250 IVDVSYGGENGFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTLKAL 309 +VDV+Y G G +A+ + + + Y +E + +++ TG YG D AL Sbjct: 252 LVDVAYQGLQGLKEAVMKAEKVVEAQMYRDAVNAMEEFKLHLAKGTGMIVYGEKDVEAAL 311 Query: 310 DLGAVEKLIVFENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQEMDVVSEEPL 369 ++GAV+ L++ E S E L Sbjct: 312 EMGAVKTLLIHE-------------------------------------------SREDL 328 Query: 370 IEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVN 413 EW+ K+ GA + + + +E F+ FGG+ +LR++++ Sbjct: 329 EEWV-EKAKSSGAQVIVVPESLAEAEWFLKTFGGLAGILRFRIS 371 >3IR9-A nrPDB Length = 166 Score = 58.9 bits (141), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 38/160 (23%), Positives = 78/160 (48%), Gaps = 3/160 (1%) Query: 254 SYGGENGFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTLKALDLGA 313 +Y E+G ++ + + E L +++ + +K + +F E+ D+GK YG L++ + Sbjct: 3 AYTDESGLSELVNAAGEKLQDLELMGQKNAVRDFFKELIADSGKVAYGESQVRANLEINS 62 Query: 314 VEKLIVFENLETIRYTFKDA---EDNEVIKFAEPEAKDKSFAIDKATGQEMDVVSEEPLI 370 V+ L++ E+L R T K + +N+ + +P + G ++V ++ Sbjct: 63 VDVLLLSEDLRAERVTTKCSVCGYENKWTRRWKPGEPAPAAGNCPKCGSSLEVTDVTDIV 122 Query: 371 EWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRY 410 + + A + F++ EG+Q + FGGI A+LRY Sbjct: 123 DEFSELADKSNAKVVFVSTDFDEGSQLMNAFGGIAAILRY 162 >3MCA-B nrPDB Length = 390 Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 26/76 (34%), Positives = 47/76 (61%), Gaps = 2/76 (2%) Query: 250 IVDVSYGGENGFNQAIELSA--EALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTLK 307 I+ S G + N+ ++ A LA+ KYVQE ++L ++D +++D K YG + LK Sbjct: 242 ILHSSTGHIHSLNEILKDPAVESKLADTKYVQEIRVLNKFYDVMNEDDRKAWYGPNHVLK 301 Query: 308 ALDLGAVEKLIVFENL 323 A +LGA+ +L++ ++L Sbjct: 302 AFELGAIGELLISDSL 317 >3J15-A nrPDB Length = 357 Score = 44.7 bits (104), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 43/152 (28%), Positives = 72/152 (47%), Gaps = 12/152 (7%) Query: 176 KHGRGGQSALRFARLREEKRHNYVRKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAK 235 +H GG+ R+ RE + + VA+ + + NV+ I+AG K D K Sbjct: 163 RHNLGGK---RYNTDRESEEMKFFHDVAKTMEE---VMKRENVEKAIVAGPGFVKEDFYK 216 Query: 236 --SELFDPRLACKVISIVDVSYGGENGFNQAIELSA--EALANVKYVQEKKLLEAYFDEI 291 E + P LA KV+ I D S G G + I+ + +E +L+E + I Sbjct: 217 FLKEKY-PELAKKVV-IEDTSVTGRTGIYEVIKRGVVDRVYQENRVAKEVQLVEKVLENI 274 Query: 292 SQDTGKFCYGIDDTLKALDLGAVEKLIVFENL 323 +++ G YG+ + +A++ GAVE L+V + L Sbjct: 275 ARNNGLVAYGLKEVEEAVNYGAVETLLVLDEL 306 >3WXM-B nrPDB Length = 376 Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 52/228 (22%), Positives = 94/228 (41%), Gaps = 45/228 (19%) Query: 191 REEKRHNYVRKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLA-KSELFDPRLACKVIS 249 RE++ YV + A+ V+ + ++AG KT +A K + P L ++ Sbjct: 187 REQEVEKYVDRAAKRIVEEAARHRSPIA---VIAGPGQLKTSVAEKVQRAMPSLK---VA 240 Query: 250 IVDVSYGGENGFNQAI--ELSAEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTLK 307 VD S GG G +A+ E L + V+ + +LE + I++ Y + L Sbjct: 241 TVDTSMGGVAGVREALRRESVTRILRELSIVEAEGVLEEFLRRIAKSRDTVAYTPGEVLA 300 Query: 308 ALDLGAVEKLIVFENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQEMDVVSEE 367 +GAV+ +++ ++T+ ++ DA EA D++ + Sbjct: 301 VARMGAVDTVLL---VDTLLHSPDDAVR---------EAVDEALRL-------------- 334 Query: 368 PLIEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVNFE 415 ++ G + I S G + V+ FGG+ A+LRY V E Sbjct: 335 ---------VESMGGRVIIIPGDSPAGERLVS-FGGVIALLRYPVPQE 372 >2QI2-A nrPDB Length = 347 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 35/147 (23%), Positives = 62/147 (42%), Gaps = 44/147 (29%) Query: 269 AEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTLKALDLGAVEKLIVFENLETIRY 328 A+ L+N + ++K++++ + + +D G YG D T AL +GA+ LI+ + + Sbjct: 239 AKLLSNERIARDKEIVDEFLVAVKKDMG--VYGRDQTESALQMGALSDLIITDEM----- 291 Query: 329 TFKDAEDNEVIKFAEPEAKDKSFAIDKATGQEMDVVSEEPLIEWLAANYKNFGATLEFIT 388 F+ ED +S +I + G + +VS Sbjct: 292 -FR-TEDGR-----------RSLSIAQTVGTRIHIVS----------------------- 315 Query: 389 DKSSEGAQFVTGFGGIGAMLRYKVNFE 415 S++ Q V FGG +LRY+V E Sbjct: 316 -VSNDPGQIVKKFGGFAGILRYRVQLE 341 >3OBW-A nrPDB Length = 364 Score = 32.7 bits (73), Expect = 0.31, Method: Compositional matrix adjust. Identities = 25/106 (23%), Positives = 53/106 (50%), Gaps = 4/106 (3%) Query: 220 GLILAGSADFKTDLAKSELFDPRLACKVISIVDVSYGGENGFNQAI--ELSAEALANVKY 277 ++LAG FK +++K + L K I I VS G ++ + ++ + + + + Sbjct: 208 AILLAGPGFFKEEVSKK--VNAILKNKKIYIDSVSSATRAGLHEVLKRDIIDKIMTDYEI 265 Query: 278 VQEKKLLEAYFDEISQDTGKFCYGIDDTLKALDLGAVEKLIVFENL 323 K +E + +++ YG++ A+++GAVE ++V E+L Sbjct: 266 AIGAKKMEKAMELLAKQPELVTYGLEQVKNAIEMGAVETVLVIEDL 311 >2VGN-A nrPDB Length = 386 Score = 32.3 bits (72), Expect = 0.37, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 38/72 (52%), Gaps = 2/72 (2%) Query: 250 IVDVSYGGENGFNQAIE--LSAEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTLK 307 I S G G N+ ++ L A L + KY +E +++ + +++D K YG + +K Sbjct: 248 IAHCSTGYLQGINEVLKNPLYASKLQDTKYSKEIMVMDEFLLHLNKDDDKAWYGEKEVVK 307 Query: 308 ALDLGAVEKLIV 319 A + GA+ L++ Sbjct: 308 AAEYGAISYLLL 319 >3IEB-A nrPDB Length = 218 Score = 32.3 bits (72), Expect = 0.41, Method: Compositional matrix adjust. Identities = 25/67 (37%), Positives = 34/67 (50%), Gaps = 4/67 (5%) Query: 38 PKGQIPLYQKMLTDEYGTASNIKSRVNRLSVLSAITSTQQKLKLYNTLPKN--GLVLYCG 95 P QI L Q LTD ASN+ S V+ + V I + + +K +TL N +L C Sbjct: 7 PMIQIALDQTNLTDAVAVASNVASYVDVIEV-GTILAFAEGMKAVSTLRHNHPNHILVC- 64 Query: 96 DIITEDG 102 D+ T DG Sbjct: 65 DMKTTDG 71 >5OLJ-A nrPDB Length = 723 Score = 31.2 bits (69), Expect = 0.83, Method: Compositional matrix adjust. Identities = 25/119 (21%), Positives = 44/119 (36%), Gaps = 1/119 (0%) Query: 12 WKVKKLVQSLEKARGNGTSMISLVIPPKGQIPLYQKMLTDEY-GTASNIKSRVNRLSVLS 70 W + RGNGT + + P Y + T+ + T S S L Sbjct: 592 WSYGGYTTLMSLCRGNGTFKAGIAVAPVADWRFYDSVYTERFMRTPKENASGYKMSSALD 651 Query: 71 AITSTQQKLKLYNTLPKNGLVLYCGDIITEDGKEKKVTFDIEPYKPINTSLYLCDNKFH 129 + Q L + + + + L + TE + + FD+ Y N S+Y + ++H Sbjct: 652 VASQLQGNLLIVSGSADDNVHLQNTMLFTEALVQANIPFDMAIYMDKNHSIYGGNTRYH 710 >5DCV-A nrPDB Length = 132 Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust. Identities = 18/51 (35%), Positives = 31/51 (60%), Gaps = 2/51 (3%) Query: 275 VKYVQEKKLLEAYFD--EISQDTGKFCYGIDDTLKALDLGAVEKLIVFENL 323 VK+ K+L E EI++DTGK G ++T KA++ G + +I+ E++ Sbjct: 8 VKFEVPKELAEKALQAVEIARDTGKIRKGTNETTKAVERGQAKLVIIAEDV 58 >5EVI-D nrPDB Length = 366 Score = 30.4 bits (67), Expect = 1.4, Method: Compositional matrix adjust. Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 7/73 (9%) Query: 221 LILAGSADFKTDLAKSELFDPRLACKVISIVDVSYGGENGFNQAIELSAEA------LAN 274 ++LAG+A + K++ +P LA + + V+ + G NGF + A+ LAN Sbjct: 286 VLLAGNASAMLNTQKADAIEPPLAAQPTAWVNKT-GSTNGFGGYVAFIAQKQLGIVILAN 344 Query: 275 VKYVQEKKLLEAY 287 Y E+++ AY Sbjct: 345 KNYPNEERVKLAY 357 >4V6W-Cc nrPDB Length = 111 Score = 29.3 bits (64), Expect = 3.4, Method: Compositional matrix adjust. Identities = 15/51 (29%), Positives = 27/51 (52%), Gaps = 2/51 (3%) Query: 279 QEKKLLEAYFDEIS--QDTGKFCYGIDDTLKALDLGAVEKLIVFENLETIR 327 ++KK LE+ ++ +GK+C G TLK L G + +++ N +R Sbjct: 6 KQKKALESTNARLALVMKSGKYCLGYKQTLKTLRQGKAKLVLIASNTPALR 56 >3JS5-A nrPDB Length = 178 Score = 28.1 bits (61), Expect = 7.2, Method: Compositional matrix adjust. Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 13/58 (22%) Query: 228 DFKTDLAKSELFDPRLACKVISIVDVSYGGENGFNQAIELSAEALAN-VKYVQEKKLL 284 DF T + +E+ DP YGGE GF++ I++ +A N + ++E KL+ Sbjct: 132 DFCTTIKTTEVPDPY------------YGGEKGFHRVIDILEDACENLIIKLEEGKLI 177 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4CRN-X nrPDB 642 0.0 5LZU-ii nrPDB 615 e-176 3E20-C nrPDB 586 e-168 4AF1-A nrPDB 461 e-130 3AGK-A nrPDB 421 e-118 4CRM-X nrPDB 386 e-108 2LLX-A nrPDB 231 5e-61 2HST-A nrPDB 199 1e-51 2KTV-A nrPDB 196 2e-50 3IR9-A nrPDB 173 1e-43 3WXM-B nrPDB 157 8e-39 3J15-A nrPDB 151 6e-37 3MCA-B nrPDB 101 6e-22 2QI2-A nrPDB 96 2e-20 Sequences not found previously or not previously below threshold: 2VGN-A nrPDB 84 1e-16 5LZY-ii nrPDB 80 2e-15 3OBW-A nrPDB 71 1e-12 3OBY-A nrPDB 65 5e-11 1X52-A nrPDB 51 1e-06 5EO3-A nrPDB 50 2e-06 3OAM-A nrPDB 37 0.023 5JTL-E nrPDB 33 0.21 4V6W-Cc nrPDB 31 1.3 3ZQJ-A nrPDB 30 2.1 4O29-A nrPDB 29 3.1 3T7V-A nrPDB 29 3.3 4QHP-A nrPDB 28 7.4 4U1E-I nrPDB 28 9.3 >4CRN-X nrPDB Length = 437 Score = 642 bits (1657), Expect = 0.0, Method: Composition-based stats. Identities = 435/437 (99%), Positives = 436/437 (99%) Query: 1 MDNEVEKNIEIWKVKKLVQSLEKARGNGTSMISLVIPPKGQIPLYQKMLTDEYGTASNIK 60 MDNEVEKNIEIWKVKKLVQSLEKARGNGTSMISLVIPPKG IPLYQKMLTDEYGTASNIK Sbjct: 1 MDNEVEKNIEIWKVKKLVQSLEKARGNGTSMISLVIPPKGLIPLYQKMLTDEYGTASNIK 60 Query: 61 SRVNRLSVLSAITSTQQKLKLYNTLPKNGLVLYCGDIITEDGKEKKVTFDIEPYKPINTS 120 SRVNRLSVLSAITSTQQKLKLYNTLPKNGLVLYCGDIITEDGKEKKVTFDIEPYKPINTS Sbjct: 61 SRVNRLSVLSAITSTQQKLKLYNTLPKNGLVLYCGDIITEDGKEKKVTFDIEPYKPINTS 120 Query: 121 LYLCDNKFHTEVLSELLQADDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRG 180 LYLCDNKFHTEVLSELLQADDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRG Sbjct: 121 LYLCDNKFHTEVLSELLQADDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRG 180 Query: 181 GQSALRFARLREEKRHNYVRKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFD 240 GQSALRFARLREEKRHNYVRKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFD Sbjct: 181 GQSALRFARLREEKRHNYVRKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFD 240 Query: 241 PRLACKVISIVDVSYGGENGFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFCY 300 PRLACKVISIVDVSYGGENGFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFC+ Sbjct: 241 PRLACKVISIVDVSYGGENGFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFCF 300 Query: 301 GIDDTLKALDLGAVEKLIVFENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQE 360 GIDDTLKALDLGAVEKLIVFENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQE Sbjct: 301 GIDDTLKALDLGAVEKLIVFENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQE 360 Query: 361 MDVVSEEPLIEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVNFEQLVDE 420 MDVVSEEPLIEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVNFEQLVDE Sbjct: 361 MDVVSEEPLIEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVNFEQLVDE 420 Query: 421 SEDEYYDEDEGSDYDFI 437 SEDEYYDEDEGSDYDFI Sbjct: 421 SEDEYYDEDEGSDYDFI 437 >5LZU-ii nrPDB Length = 459 Score = 615 bits (1585), Expect = e-176, Method: Composition-based stats. Identities = 292/428 (68%), Positives = 353/428 (82%), Gaps = 3/428 (0%) Query: 6 EKNIEIWKVKKLVQSLEKARGNGTSMISLVIPPKGQIPLYQKMLTDEYGTASNIKSRVNR 65 ++N+EIWK+KKL++SLE ARGNGTSMISL+IPPK QI KML DE+GTASNIKSRVNR Sbjct: 31 DRNVEIWKIKKLIKSLEAARGNGTSMISLIIPPKDQISRVAKMLADEFGTASNIKSRVNR 90 Query: 66 LSVLSAITSTQQKLKLYNTLPKNGLVLYCGDIITEDGKEKKVTFDIEPYKPINTSLYLCD 125 LSVL AITS QQ+LKLYN +P NGLV+YCG I+TE+GKEKKV D EP+KPINTSLYLCD Sbjct: 91 LSVLGAITSVQQRLKLYNKVPPNGLVVYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCD 150 Query: 126 NKFHTEVLSELLQADDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRGGQSAL 185 NKFHTE L+ LL D KFGFIV+DG G LFG++ GNTR VLHKFTVDLPKKHGRGGQSAL Sbjct: 151 NKFHTEALTALLSDDSKFGFIVIDGSGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSAL 210 Query: 186 RFARLREEKRHNYVRKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFDPRLAC 245 RFARLR EKRHNYVRKVAE AVQ FI+ DKVNV GL+LAGSADFKT+L++S++FD RL Sbjct: 211 RFARLRMEKRHNYVRKVAETAVQLFISGDKVNVAGLVLAGSADFKTELSQSDMFDQRLQS 270 Query: 246 KVISIVDVSYGGENGFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDT 305 KV+ +VD+SYGGENGFNQAIELS E L+NVK++QEKKL+ YFDEISQDTGK+C+G++DT Sbjct: 271 KVLKLVDISYGGENGFNQAIELSTEVLSNVKFIQEKKLIGRYFDEISQDTGKYCFGVEDT 330 Query: 306 LKALDLGAVEKLIVFENLETIRYTFKD--AEDNEVIKFAEPEAKDKSFAIDKATGQEMDV 363 LKAL++GAVE LIV+ENL+ +RY E+ +++ + KDKS DK TGQE ++ Sbjct: 331 LKALEMGAVEILIVYENLDIMRYVLHCQGTEEEKILYLTPEQEKDKSHFTDKETGQEHEL 390 Query: 364 VSEEPLIEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVNFEQL-VDESE 422 + PL+EW A NYK FGATLE +TDKS EG+QFV GFGGIG +LRY+V+F+ + + Sbjct: 391 IESMPLLEWFANNYKKFGATLEIVTDKSQEGSQFVKGFGGIGGILRYRVDFQGMEYQGGD 450 Query: 423 DEYYDEDE 430 DE++D D+ Sbjct: 451 DEFFDLDD 458 >3E20-C nrPDB Length = 441 Score = 586 bits (1511), Expect = e-168, Method: Composition-based stats. Identities = 274/428 (64%), Positives = 344/428 (80%), Gaps = 4/428 (0%) Query: 6 EKNIEIWKVKKLVQSLEKARGNGTSMISLVIPPKGQIPLYQKMLTDEYGTASNIKSRVNR 65 EK IEIWK+++LV+ L GNGTSMI+L+IPP QI Y ML +EYGTASNIKSRVNR Sbjct: 14 EKAIEIWKIRRLVKQLINCHGNGTSMITLIIPPGEQISRYSNMLAEEYGTASNIKSRVNR 73 Query: 66 LSVLSAITSTQQKLKLYNTLPKNGLVLYCGDIITEDGKEKKVTFDIEPYKPINTSLYLCD 125 LSVLSAITST+++LKLYN +P NGLV+YCG++I E K +K+ D EP+KPINTS YLCD Sbjct: 74 LSVLSAITSTRERLKLYNKVPDNGLVIYCGEVIMEGNKTRKLNIDFEPFKPINTSQYLCD 133 Query: 126 NKFHTEVLSELLQADDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRGGQSAL 185 NKFHTE L+ELL++D +FGFIVMDG TL+G VSG+ R VL +FTVDLPKKHGRGGQSAL Sbjct: 134 NKFHTEALAELLESDQRFGFIVMDGHQTLYGVVSGSAREVLQRFTVDLPKKHGRGGQSAL 193 Query: 186 RFARLREEKRHNYVRKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFDPRLAC 245 RFARLR+EKRHNYVRKVAE AVQ+FIT+DK NV G++LAGSADFKT+L +S+LFD RL Sbjct: 194 RFARLRDEKRHNYVRKVAEGAVQHFITDDKPNVAGIVLAGSADFKTELGQSDLFDQRLQS 253 Query: 246 KVISIVDVSYGGENGFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDT 305 ++I VDVSYGG+ GFNQAIEL+A+ L+NVKYVQEKKL++ +FDEIS D+GK+C+G+ DT Sbjct: 254 RIIKTVDVSYGGDAGFNQAIELAADTLSNVKYVQEKKLIQRFFDEISLDSGKYCFGVVDT 313 Query: 306 LKALDLGAVEKLIVFENLETIRYTFKDAEDNEVIKFAEPEAKDK----SFAIDKATGQEM 361 + AL GAVE L+ F +L+ IRY FK++E N VI + E ++K SF +DK TG EM Sbjct: 314 MNALQEGAVETLLCFADLDMIRYEFKNSEGNPVITYMTKEQEEKDSTNSFLLDKDTGAEM 373 Query: 362 DVVSEEPLIEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVNFEQLVDES 421 ++VS L EWLA +YK++GA LEF++D+S EG QFV GFGGIGA++RY+++ L ES Sbjct: 374 ELVSSMLLSEWLAEHYKDYGANLEFVSDRSQEGMQFVKGFGGIGAVMRYQLDLSMLDPES 433 Query: 422 EDEYYDED 429 ++ Y D D Sbjct: 434 DEFYSDSD 441 >4AF1-A nrPDB Length = 416 Score = 461 bits (1186), Expect = e-130, Method: Composition-based stats. Identities = 126/406 (31%), Positives = 212/406 (52%), Gaps = 15/406 (3%) Query: 12 WKVKKLVQSLEKARGNGTSMISLVIPPKGQIPLYQKMLTDEYGTASNIKSRVNRLSVLSA 71 ++ +K+++ L+ G+GT ++++ IPP QI +T E+ ASNIKS+ R +V A Sbjct: 15 YEFRKVIEELKDYEGSGTQLVTIYIPPDKQISDVVAHVTQEHSEASNIKSKQTRTNVQDA 74 Query: 72 ITSTQQKLKLYNTLPK-NGLVLYCGDIITEDGKEKKVTFDIE-PYKPINTSLYLCDNKFH 129 +TS + +L+ Y+T P NG+V++ G + + G+ VT +E P +PI + Y CD+ F Sbjct: 75 LTSIKDRLRYYDTFPPDNGMVVFSGAVDSGGGRTDMVTEVLESPPQPIESFRYHCDSAFL 134 Query: 130 TEVLSELLQADDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRGGQSALRFAR 189 TE L+E+L +G IV+D + + G + G + +P K +GGQSA RFAR Sbjct: 135 TEPLAEMLGDKGLYGLIVLDRRESNVGWLKGKRVQPVKSAESLVPGKQRKGGQSAQRFAR 194 Query: 190 LREEKRHNYVRKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFDPRLACKVIS 249 LR E N+ ++VA +A F+ + + G+++ G + K + + L KV+ Sbjct: 195 LRLEAIDNFYQEVAGMADDLFVP-KRHEIDGILVGGPSPTKDEFLDGDYLHHELQDKVLG 253 Query: 250 IVDVSYGGENGFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFC-YGIDDTLKA 308 DVSY E+G + ++ ALA + +K +E +F+E+ + GK YG + T + Sbjct: 254 KFDVSYTDESGLSDLVDAGQAALAEADLMDDKSDMEEFFEEL--NGGKLATYGFEQTRRN 311 Query: 309 LDLGAVEKLIVFENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAIDKA----TGQEMDVV 364 L +G+V++L+V E+L ++ D+E E E D+ + G+E V Sbjct: 312 LIMGSVDRLLVSEDLREDVVIYECPNDHE-----EYETIDRRNTSPEHTCSDCGEEATEV 366 Query: 365 SEEPLIEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRY 410 E I+ L + G FI+ +G Q +T FGG +LRY Sbjct: 367 DREDAIDHLMSIADQRGTETHFISTDFEKGEQLLTAFGGYAGILRY 412 >3AGK-A nrPDB Length = 373 Score = 421 bits (1081), Expect = e-118, Method: Composition-based stats. Identities = 104/404 (25%), Positives = 187/404 (46%), Gaps = 51/404 (12%) Query: 13 KVKKLVQSLEKARGNGTSMISLVIPPKGQIPLYQKMLTDEYGTASNIKSRVNRLSVLSAI 72 ++ +L++ L+K T ++SL IPP + +L EY NIK + R +V A+ Sbjct: 16 ELARLLKELKKWSAPATVLLSLYIPPGRPLSDVMTLLRQEYSITDNIKLKRTRQAVKRAL 75 Query: 73 TSTQQKLKLYNTLPKNGLVLYCGDIITEDGKEKKVTFDIEPYKPINTSLYLCDNKFHTEV 132 ++ +L++ + P NGLVL+CG+ ++ E F P +PI Y D +F T+ Sbjct: 76 SAAMDRLQMLTSTPPNGLVLFCGEDMSTGKFE---CFMFSPPEPIRVFYYRTDKRFITDF 132 Query: 133 LSELLQADDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRGGQSALRFARLRE 192 L ++++ ++ G I+++ G + G VL + +P KH GGQS R+ R+ E Sbjct: 133 LEDMVEDNNAIGIIIVERDQATIGLLKGARLEVLKELEGFVPGKHKMGGQSQRRYERIIE 192 Query: 193 EKRHNYVRKVAEVAVQNFIT-NDKVNVKGLILAGSADFKTDLAKSELFDPRLACKVIS-- 249 + + +KV E A + +K +KG+I+AG K + + D RL K+++ Sbjct: 193 QMVDEFFKKVGEEASNLLVPLAEKGVLKGVIVAGPGLAKQEFVEGNYLDYRLK-KILAPE 251 Query: 250 IVDVSYGGENGFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTLKAL 309 +VDV+Y G G +A+ + + + Y +E + +++ TG YG D AL Sbjct: 252 LVDVAYQGLQGLKEAVMKAEKVVEAQMYRDAVNAMEEFKLHLAKGTGMIVYGEKDVEAAL 311 Query: 310 DLGAVEKLIVFENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQEMDVVSEEPL 369 ++GAV+ L++ E S E L Sbjct: 312 EMGAVKTLLIHE-------------------------------------------SREDL 328 Query: 370 IEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVN 413 EW+ K+ GA + + + +E F+ FGG+ +LR++++ Sbjct: 329 EEWV-EKAKSSGAQVIVVPESLAEAEWFLKTFGGLAGILRFRIS 371 >4CRM-X nrPDB Length = 282 Score = 386 bits (992), Expect = e-108, Method: Composition-based stats. Identities = 282/282 (100%), Positives = 282/282 (100%) Query: 140 DDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRGGQSALRFARLREEKRHNYV 199 DDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRGGQSALRFARLREEKRHNYV Sbjct: 1 DDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRGGQSALRFARLREEKRHNYV 60 Query: 200 RKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFDPRLACKVISIVDVSYGGEN 259 RKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFDPRLACKVISIVDVSYGGEN Sbjct: 61 RKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFDPRLACKVISIVDVSYGGEN 120 Query: 260 GFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTLKALDLGAVEKLIV 319 GFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTLKALDLGAVEKLIV Sbjct: 121 GFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTLKALDLGAVEKLIV 180 Query: 320 FENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQEMDVVSEEPLIEWLAANYKN 379 FENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQEMDVVSEEPLIEWLAANYKN Sbjct: 181 FENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQEMDVVSEEPLIEWLAANYKN 240 Query: 380 FGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVNFEQLVDES 421 FGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVNFEQLVDES Sbjct: 241 FGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVNFEQLVDES 282 >2LLX-A nrPDB Length = 150 Score = 231 bits (589), Expect = 5e-61, Method: Composition-based stats. Identities = 100/134 (74%), Positives = 115/134 (85%) Query: 6 EKNIEIWKVKKLVQSLEKARGNGTSMISLVIPPKGQIPLYQKMLTDEYGTASNIKSRVNR 65 ++N+EIWK+KKL++SLE ARGNGTSMISL+IPPK QI KML DE+GTASNIKSRVNR Sbjct: 9 DRNVEIWKIKKLIKSLEAARGNGTSMISLIIPPKDQISRVAKMLADEFGTASNIKSRVNR 68 Query: 66 LSVLSAITSTQQKLKLYNTLPKNGLVLYCGDIITEDGKEKKVTFDIEPYKPINTSLYLCD 125 LSVL AITS QQ+LKLYN +P NGLV+YCG I+TE+GKEKKV D EP+KPINTSLYLCD Sbjct: 69 LSVLGAITSVQQRLKLYNKVPPNGLVVYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCD 128 Query: 126 NKFHTEVLSELLQA 139 NKFHTE L+ LL Sbjct: 129 NKFHTEALTALLSD 142 >2HST-A nrPDB Length = 143 Score = 199 bits (507), Expect = 1e-51, Method: Composition-based stats. Identities = 105/137 (76%), Positives = 118/137 (86%) Query: 137 LQADDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRGGQSALRFARLREEKRH 196 L D KFGFIV+DG G LFG++ GNTR VLHKFTVDLPKKHGRGGQSALRFARLR EKRH Sbjct: 1 LSDDSKFGFIVIDGSGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRH 60 Query: 197 NYVRKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFDPRLACKVISIVDVSYG 256 NYVRKVAE AVQ FI+ DKVNV GL+LAGSADFKT+L++S++FD RL KV+ +VD+SYG Sbjct: 61 NYVRKVAETAVQLFISGDKVNVAGLVLAGSADFKTELSQSDMFDQRLQSKVLKLVDISYG 120 Query: 257 GENGFNQAIELSAEALA 273 GENGFNQAIELS E L Sbjct: 121 GENGFNQAIELSTEVLE 137 >2KTV-A nrPDB Length = 170 Score = 196 bits (498), Expect = 2e-50, Method: Composition-based stats. Identities = 88/161 (54%), Positives = 121/161 (75%), Gaps = 3/161 (1%) Query: 273 ANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTLKALDLGAVEKLIVFENLETIRYTFKD 332 +NVK++QEKKL+ YFDEISQDTGK+C+G++DTLKAL++GAVE LIV+ENL+ +RY Sbjct: 1 SNVKFIQEKKLIGRYFDEISQDTGKYCFGVEDTLKALEMGAVEILIVYENLDIMRYVLHC 60 Query: 333 --AEDNEVIKFAEPEAKDKSFAIDKATGQEMDVVSEEPLIEWLAANYKNFGATLEFITDK 390 E+ +++ + KDKS DK TGQE +++ PL+EW A NYK FGATLE +TDK Sbjct: 61 QGTEEEKILYLTPEQEKDKSHFTDKETGQEHELIESMPLLEWFANNYKKFGATLEIVTDK 120 Query: 391 SSEGAQFVTGFGGIGAMLRYKVNFEQL-VDESEDEYYDEDE 430 S EG+QFV GFGGIG +LRY+V+F+ + +DE++D D+ Sbjct: 121 SQEGSQFVKGFGGIGGILRYRVDFQGMEYQGGDDEFFDLDD 161 >3IR9-A nrPDB Length = 166 Score = 173 bits (438), Expect = 1e-43, Method: Composition-based stats. Identities = 38/160 (23%), Positives = 78/160 (48%), Gaps = 3/160 (1%) Query: 254 SYGGENGFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTLKALDLGA 313 +Y E+G ++ + + E L +++ + +K + +F E+ D+GK YG L++ + Sbjct: 3 AYTDESGLSELVNAAGEKLQDLELMGQKNAVRDFFKELIADSGKVAYGESQVRANLEINS 62 Query: 314 VEKLIVFENLETIRYTFKDA---EDNEVIKFAEPEAKDKSFAIDKATGQEMDVVSEEPLI 370 V+ L++ E+L R T K + +N+ + +P + G ++V ++ Sbjct: 63 VDVLLLSEDLRAERVTTKCSVCGYENKWTRRWKPGEPAPAAGNCPKCGSSLEVTDVTDIV 122 Query: 371 EWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRY 410 + + A + F++ EG+Q + FGGI A+LRY Sbjct: 123 DEFSELADKSNAKVVFVSTDFDEGSQLMNAFGGIAAILRY 162 >3WXM-B nrPDB Length = 376 Score = 157 bits (397), Expect = 8e-39, Method: Composition-based stats. Identities = 61/296 (20%), Positives = 114/296 (38%), Gaps = 57/296 (19%) Query: 125 DNKFHTEVLSELLQADDKFGFIV--MDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRGGQ 182 D + + L L + ++ +D ++G+ +L + LP K Sbjct: 129 DKGWSEQELERLASGRARGTAVIAAVDYDEFALAVLAGHGMKILEDTSARLPGKDDPS-- 186 Query: 183 SALRFARLREEKRHNYVRKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLA-KSELFDP 241 RE++ YV + A+ V+ + ++AG KT +A K + P Sbjct: 187 --------REQEVEKYVDRAAKRIVEEAARHRSPIA---VIAGPGQLKTSVAEKVQRAMP 235 Query: 242 RLACKVISIVDVSYGGENGFNQAI--ELSAEALANVKYVQEKKLLEAYFDEISQDTGKFC 299 L ++ VD S GG G +A+ E L + V+ + +LE + I++ Sbjct: 236 SLK---VATVDTSMGGVAGVREALRRESVTRILRELSIVEAEGVLEEFLRRIAKSRDTVA 292 Query: 300 YGIDDTLKALDLGAVEKLIVFENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQ 359 Y + L +GAV+ +++ ++T+ ++ DA EA D++ + Sbjct: 293 YTPGEVLAVARMGAVDTVLL---VDTLLHSPDDAVR---------EAVDEALRL------ 334 Query: 360 EMDVVSEEPLIEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVNFE 415 ++ G + I S G + V+ FGG+ A+LRY V E Sbjct: 335 -----------------VESMGGRVIIIPGDSPAGERLVS-FGGVIALLRYPVPQE 372 >3J15-A nrPDB Length = 357 Score = 151 bits (381), Expect = 6e-37, Method: Composition-based stats. Identities = 79/386 (20%), Positives = 145/386 (37%), Gaps = 66/386 (17%) Query: 35 VIPPKGQIPLYQKMLTDEYGTASNIKS-RVNRLSVLSAITSTQQKL-KLYNTLPKNGLVL 92 +I P + Y K L + A ++++ +V + V + + + K N + G ++ Sbjct: 29 IIDPGDIV--YAKTLRKQAQRADSLRAEKVEVIPVFLGVQAEKINFHKFANQVRVTGPIV 86 Query: 93 YCGDIITEDGKEKKVTFDIEPYKPINTSLYLCDNKFHTEVLSELLQADDK--FGFIVMDG 150 Y GK + + I + + H E L E + A + +V+D Sbjct: 87 YASREDVPLGKYHTIAIEQGTVVTIQKPRW---KEHHIERLKEAVAASKRARVMIVVIDD 143 Query: 151 QGTLFGSVSGNTRTVLHKFTVDLPKKHGRGGQSALRFARLREEKRHNYVRKVAEVAVQNF 210 V +L+ +H GG+ R+ RE + + VA+ + Sbjct: 144 GEADMALVREYGVEILNSI------RHNLGGK---RYNTDRESEEMKFFHDVAKTMEE-- 192 Query: 211 ITNDKVNVKGLILAGSADFKTDLAK--SELFDPRLACKVISIVDVSYGGENGFNQAIELS 268 + NV+ I+AG K D K E + P LA KV+ I D S G G + I+ Sbjct: 193 -VMKRENVEKAIVAGPGFVKEDFYKFLKEKY-PELAKKVV-IEDTSVTGRTGIYEVIKRG 249 Query: 269 A--EALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTLKALDLGAVEKLIVFENLETI 326 + +E +L+E + I+++ G YG+ + +A++ GAVE L+V + L Sbjct: 250 VVDRVYQENRVAKEVQLVEKVLENIARNNGLVAYGLKEVEEAVNYGAVETLLVLDEL--- 306 Query: 327 RYTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQEMDVVSEEPLIEWLAANYKNFGATLEF 386 K +V E L + + Sbjct: 307 ---LKGELREKV--------------------------------EELMDAVRYSRGEVVV 331 Query: 387 ITDKSSEGAQFVTGFGGIGAMLRYKV 412 ++ + EG + + GG+ A+LR++V Sbjct: 332 VSSE-HEGGEKLKALGGLAALLRFRV 356 >3MCA-B nrPDB Length = 390 Score = 101 bits (252), Expect = 6e-22, Method: Composition-based stats. Identities = 56/286 (19%), Positives = 102/286 (35%), Gaps = 62/286 (21%) Query: 140 DDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRGGQSALRFARLREEKRHNYV 199 + + G +V+D ++ + + +P+K RG SA ++ + Sbjct: 134 NAEIGAVVLDEGLANICLITDYMTILRQRIDQVIPRK-RRGDSSAY------QKGLDKFY 186 Query: 200 RKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFDPRLACKV-----------I 248 V + F D +K +ILA L + +A K+ Sbjct: 187 DSVFQSINSEF---DFDKLKVVILASPGFVARGLYD---YIFSMAVKLDLKQIVKSKNKF 240 Query: 249 SIVDVSYGGENGFNQAIELSA--EALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTL 306 I+ S G + N+ ++ A LA+ KYVQE ++L ++D +++D K YG + L Sbjct: 241 VILHSSTGHIHSLNEILKDPAVESKLADTKYVQEIRVLNKFYDVMNEDDRKAWYGPNHVL 300 Query: 307 KALDLGAVEKLIVFENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQEMDVVSE 366 KA +LGA+ +L++ ++L + A + + Sbjct: 301 KAFELGAIGELLISDSL---FRSSDIATRKKWVS-------------------------- 331 Query: 367 EPLIEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRYKV 412 L K + + G Q GI A+L Y V Sbjct: 332 ------LVEGVKEINCPVYIFSSLHESGKQL-DLLSGIAAILTYPV 370 >2QI2-A nrPDB Length = 347 Score = 96.4 bits (238), Expect = 2e-20, Method: Composition-based stats. Identities = 40/210 (19%), Positives = 74/210 (35%), Gaps = 49/210 (23%) Query: 208 QNFITNDKVNVKGLILAGSADFKTDLAKSELFDPRLACKVISIVDVSYGGENGFNQAIE- 266 + K +I+ G + A + + VI + + I Sbjct: 179 DQIVNALKNYSNSIIILGPGFARDRFA---RYCAQRGVNVIGSFPANRTDSGAVYEFITS 235 Query: 267 -LSAEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTLKALDLGAVEKLIVFENLET 325 A+ L+N + ++K++++ + + +D G YG D T AL +GA+ LI+ + + Sbjct: 236 ADGAKLLSNERIARDKEIVDEFLVAVKKDMG--VYGRDQTESALQMGALSDLIITDEM-- 291 Query: 326 IRYTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQEMDVVSEEPLIEWLAANYKNFGATLE 385 E +S +I + G + +VS Sbjct: 292 ----------------FRTEDGRRSLSIAQTVGTRIHIVSV------------------- 316 Query: 386 FITDKSSEGAQFVTGFGGIGAMLRYKVNFE 415 S++ Q V FGG +LRY+V E Sbjct: 317 -----SNDPGQIVKKFGGFAGILRYRVQLE 341 >2VGN-A nrPDB Length = 386 Score = 84.1 bits (206), Expect = 1e-16, Method: Composition-based stats. Identities = 52/309 (16%), Positives = 112/309 (36%), Gaps = 57/309 (18%) Query: 126 NKFHTEVLSEL--LQADDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRGGQS 183 NKF ++L+E ++ +V+ V+ ++ + K +PKK Sbjct: 123 NKFMQKLLNEACNIEYKSDTAAVVLQEGIAHVCLVTSSSTILKQKIEYSMPKKKRT--TD 180 Query: 184 ALRFARLREEKRHNYVRKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKS--ELFDP 241 L+F +EK + + + ++ + +K +IL + L + + Sbjct: 181 VLKF----DEKTEKFYKAIYSAMKKDLNFDK---LKTIILCSPGFYAKILMDKIFQYAEE 233 Query: 242 RLACKVIS------IVDVSYGGENGFNQAIELS--AEALANVKYVQEKKLLEAYFDEISQ 293 K++ I S G G N+ ++ A L + KY +E +++ + +++ Sbjct: 234 EHNKKILDNKGMFFIAHCSTGYLQGINEVLKNPLYASKLQDTKYSKEIMVMDEFLLHLNK 293 Query: 294 DTGKFCYGIDDTLKALDLGAVEKLIVFENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAI 353 D K YG + +KA + GA+ L++ + + ++ A+ E +K Sbjct: 294 DDDKAWYGEKEVVKAAEYGAISYLLLTDKV---LHSDNIAQREEYLK------------- 337 Query: 354 DKATGQEMDVVSEEPLIEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVN 413 L + ++ G ++ S G + GI +L+Y + Sbjct: 338 -------------------LMDSVESNGGKALVLSTLHSLGEEL-DQLTGIACILKYPLP 377 Query: 414 FEQLVDESE 422 D E Sbjct: 378 DLDEDDGEE 386 >5LZY-ii nrPDB Length = 403 Score = 79.8 bits (195), Expect = 2e-15, Method: Composition-based stats. Identities = 48/277 (17%), Positives = 92/277 (33%), Gaps = 61/277 (22%) Query: 168 KFTVDLPKKHGRGGQSALRFARLREEKRHNYVRKVAEVAVQNFITNDKVNVKGLILAGSA 227 K V++P+K +G S + + +V + A+Q I D VK +++A Sbjct: 162 KVEVNIPRK-RKGNCSQH------DRALERFYEQVVQ-AIQRHIHFD--VVKCILVASPG 211 Query: 228 DFKTDLAK---------SELFDPRLACKVISIVDVSYGGENGFNQAIELS--AEALANVK 276 + K + V S G + +A+ A L++ K Sbjct: 212 FVREQFCDYMFQQAVKTDNKLLLENRSKFLQ-VHASSGHKYSLKEALCDPTVASRLSDTK 270 Query: 277 YVQEKKLLEAYFDEISQDTGKFCYGIDDTLKALDLGAVEKLIVFENLETIRYTFKDAEDN 336 E K L+ ++ + + + YG+ KA + A++ L++ + L Sbjct: 271 AAGEVKALDDFYKMLQHEPDRAFYGLKQVEKANEAMAIDTLLISDEL------------- 317 Query: 337 EVIKFAEPEAKDKSFAIDKATGQEMDVVSEEPLIEWLAANYKNFGATLEFITDKSSEGAQ 396 V+ L + K T+ + G Q Sbjct: 318 ----------------------FRHQDVATRSRYVRLVDSVKENAGTVRIFSSLHVSGEQ 355 Query: 397 FVTGFGGIGAMLRYKVNFEQLVDESEDEYYDEDEGSD 433 + G+ A+LR+ V E E + E++GS+ Sbjct: 356 L-SQLTGVAAILRFPVP-ELSDQEGDS--SSEEDGSE 388 >3OBW-A nrPDB Length = 364 Score = 71.0 bits (172), Expect = 1e-12, Method: Composition-based stats. Identities = 39/216 (18%), Positives = 84/216 (38%), Gaps = 41/216 (18%) Query: 200 RKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFDPRLACKVISIVDVSYGGEN 259 + E+A + + + ++LAG FK +++K + L K I I VS Sbjct: 188 QNALEIATELAEYVKQYDPDAILLAGPGFFKEEVSK--KVNAILKNKKIYIDSVSSATRA 245 Query: 260 GFNQAIEL--SAEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTLKALDLGAVEKL 317 G ++ ++ + + + + K +E + +++ YG++ A+++GAVE + Sbjct: 246 GLHEVLKRDIIDKIMTDYEIAIGAKKMEKAMELLAKQPELVTYGLEQVKNAIEMGAVETV 305 Query: 318 IVFENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQEMDVVSEEPLIEWLAANY 377 +V E+L + D+ E IE + + Sbjct: 306 LVIEDL---------------------------LSSDEQ---------ERLTIERMLEDI 329 Query: 378 KNFGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVN 413 +N + + +S + GI A+LR+++N Sbjct: 330 ENKRGEVILVPKESPIYFEL-KNLTGILAILRFRIN 364 >3OBY-A nrPDB Length = 352 Score = 65.2 bits (157), Expect = 5e-11, Method: Composition-based stats. Identities = 42/226 (18%), Positives = 85/226 (37%), Gaps = 45/226 (19%) Query: 193 EKRHNYVRKVAEVAVQNF----ITNDKVNVKGLILAGSADFKTDLAKSELFDPRLACKVI 248 E+R Y + + + + F + + K LI+AG K D K Sbjct: 156 EERMGYGKGMGDSRKEFFGEVAAKLESFDFKYLIVAGPGFAKNDFLDFLKERYPEMAKNA 215 Query: 249 SIVDVSYGGENGFNQAIEL--SAEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTL 306 +VDVS G GF + ++ + + V+ +E + ++ + I++ + YG+D+ Sbjct: 216 VVVDVSSVGSRGFIEILKRRVVDKIVGEVRLAEEAEYIDRLLEGIAKGE-RVAYGLDEVR 274 Query: 307 KALDLGAVEKLIVFENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQEMDVVSE 366 +A + A+E L+V + F E + Sbjct: 275 EAHNYRAIEVLLVADE-------FLLEEREKWD--------------------------- 300 Query: 367 EPLIEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRYKV 412 ++ L + G + ++ + G + ++ GGI A+LR+ V Sbjct: 301 ---VDGLLREVEESGGKVVIMSTEFEPGKRLMS-LGGIAALLRFNV 342 >1X52-A nrPDB Length = 124 Score = 50.9 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 24/146 (16%), Positives = 47/146 (32%), Gaps = 36/146 (24%) Query: 268 SAEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTLKALDLGAVEKLIVFENLETIR 327 A L++ K E K L+ ++ + + + YG+ KA + A++ L++ + L Sbjct: 9 VASRLSDTKAAGEVKALDDFYKMLQHEPDRAFYGLKQVEKANEAMAIDTLLISDEL---- 64 Query: 328 YTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQEMDVVSEEPLIEWLAANYKNFGATLEFI 387 V+ L + K T+ Sbjct: 65 -------------------------------FRHQDVATRSRYVRLVDSVKENAGTVRIF 93 Query: 388 TDKSSEGAQFVTGFGGIGAMLRYKVN 413 + G Q + G+ A+LR+ V Sbjct: 94 SSLHVSGEQL-SQLTGVAAILRFPVP 118 >5EO3-A nrPDB Length = 121 Score = 50.2 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 25/151 (16%), Positives = 49/151 (32%), Gaps = 37/151 (24%) Query: 272 LANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTLKALDLGAVEKLIVFENLETIRYTFK 331 L++ K E K L+ ++ + + + YG+ KA + A++ L++ + L Sbjct: 2 LSDTKAAGEVKALDDFYKMLQHEPDRAFYGLKQVEKANEAMAIDTLLISDEL-------- 53 Query: 332 DAEDNEVIKFAEPEAKDKSFAIDKATGQEMDVVSEEPLIEWLAANYKNFGATLEFITDKS 391 V+ L + K T+ + Sbjct: 54 ---------------------------FRHQDVATRSRYVRLVDSVKENAGTVRIFSSLH 86 Query: 392 SEGAQFVTGFGGIGAMLRYKVNFEQLVDESE 422 G Q + G+ A+LR+ V E E + Sbjct: 87 VSGEQL-SQLTGVAAILRFPVP-ELSDQEGD 115 >3OAM-A nrPDB Length = 252 Score = 36.7 bits (83), Expect = 0.023, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 21/50 (42%) Query: 358 GQEMDVVSEEPLIEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAM 407 G+ + + +P+I+W+ GA I Q V FGG+ M Sbjct: 18 GKPLADIGGKPMIQWVYEQAMQAGADRVIIATDDERVEQAVQAFGGVVCM 67 >5JTL-E nrPDB Length = 471 Score = 33.2 bits (74), Expect = 0.21, Method: Composition-based stats. Identities = 25/147 (17%), Positives = 45/147 (30%), Gaps = 13/147 (8%) Query: 262 NQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDT-LKALDLGAV------ 314 Q + +A + + Q+K LL + D + G T +D AV Sbjct: 256 YQLVSDAASLNSVTEANQQKPLLGLFAD---GNMPVRWLGPKATYHGNIDKPAVTCTPNP 312 Query: 315 ---EKLIVFENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQEMDVVSEEPLIE 371 + + + + E + DK GQ + V + ++ Sbjct: 313 QRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQ 372 Query: 372 WLAANYKNFGATLEFITDKSSEGAQFV 398 K G TL +T + +Q V Sbjct: 373 RALEFAKKEGNTLVIVTADHAHASQIV 399 >4V6W-Cc nrPDB Length = 111 Score = 30.9 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 16/55 (29%), Positives = 28/55 (50%), Gaps = 2/55 (3%) Query: 275 VKYVQEKKLLEAYFDEISQ--DTGKFCYGIDDTLKALDLGAVEKLIVFENLETIR 327 V ++KK LE+ ++ +GK+C G TLK L G + +++ N +R Sbjct: 2 VAVKKQKKALESTNARLALVMKSGKYCLGYKQTLKTLRQGKAKLVLIASNTPALR 56 >3ZQJ-A nrPDB Length = 993 Score = 30.1 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 27/70 (38%), Gaps = 7/70 (10%) Query: 157 SVSGNTRTVLHKFTVDLPKKH-------GRGGQSALRFARLREEKRHNYVRKVAEVAVQN 209 V G L +DLP+ G+S+L F + E + YV ++ A Q Sbjct: 27 IVKGAREHNLRSVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSAYARQF 86 Query: 210 FITNDKVNVK 219 DK +V Sbjct: 87 LGQMDKPDVD 96 >4O29-A nrPDB Length = 208 Score = 29.4 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 21/119 (17%), Positives = 44/119 (36%), Gaps = 7/119 (5%) Query: 42 IPLYQKMLTDEYGTASNIKSRVNRLSVLSA----ITSTQQKLKLYNTLPKNGLVLYCGDI 97 + L K L +E +KS + ++L+ + ++ Y P L L+ G Sbjct: 1 MALMAKRLVEELERDGIVKSERVKRALLTVPREEFVLPEYRMMAYEDRP---LPLFAGAT 57 Query: 98 ITEDGKEKKVTFDIEPYKPINTSLYLCDNKFHTEVLSELLQADDKFGFIVMDGQGTLFG 156 I+ + IEP + + +H V +E ++ + I + + +F Sbjct: 58 ISAPHMVAMMCELIEPRPGMKILEVGTGSGYHAAVCAEAIEKKGRIYTIEIVKELAVFA 116 >3T7V-A nrPDB Length = 350 Score = 29.4 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 21/43 (48%) Query: 28 GTSMISLVIPPKGQIPLYQKMLTDEYGTASNIKSRVNRLSVLS 70 G ++++ ++PP Q+ D +IKS V RL ++ Sbjct: 293 GANIVTSILPPDSQLEGVANYDRDLEERDRDIKSVVRRLEIMG 335 >4QHP-A nrPDB Length = 870 Score = 28.2 bits (61), Expect = 7.4, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 28/68 (41%), Gaps = 7/68 (10%) Query: 161 NTRTVLHKFTVDLPKKHGRGGQSALRFARLREEKRHNYVRKVAEVAVQNF------ITND 214 R+++ F+ ++P H G S RF + + + +VA VQ F + Sbjct: 782 KARSLIGSFSRNVPHFHAEDG-SGYRFIADKVIEIDRFNPQVAARLVQAFNLCNKLEPHR 840 Query: 215 KVNVKGLI 222 K VK + Sbjct: 841 KNLVKQAL 848 >4U1E-I nrPDB Length = 347 Score = 27.8 bits (60), Expect = 9.3, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 30/80 (37%), Gaps = 5/80 (6%) Query: 95 GDIITEDGKEKKVTFDIEPYKPINTSLYLCDNKFHTEVLSELLQADDKFGFIVMDGQGTL 154 G I K+ K+ Y N Y+ H + +S++ + D FI Sbjct: 165 GKYIIAGHKDGKI----SKYDVSNNYEYVDSIDLHEKSISDMQFSPDLTYFITSSRDTNS 220 Query: 155 FGSVSGNTRTVLHKFTVDLP 174 F V +T VL K+ D P Sbjct: 221 F-LVDVSTLQVLKKYETDCP 239 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.125 0.299 Lambda K H 0.267 0.0384 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,080,404 Number of Sequences: 36641 Number of extensions: 521316 Number of successful extensions: 1725 Number of sequences better than 10.0: 28 Number of HSP's better than 10.0 without gapping: 42 Number of HSP's successfully gapped in prelim test: 21 Number of HSP's that attempted gapping in prelim test: 1634 Number of HSP's gapped (non-prelim): 74 length of query: 437 length of database: 10,336,785 effective HSP length: 100 effective length of query: 337 effective length of database: 6,672,685 effective search space: 2248694845 effective search space used: 2248694845 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 60 (27.8 bits)