BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P12268 (514 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6I0M-A nrPDB 1055 0.0 1JCN-A nrPDB 903 0.0 4Z87-A nrPDB 655 0.0 4AF0-B nrPDB 613 e-176 4XTI-A nrPDB 417 e-117 1VRD-A nrPDB 361 e-100 3TSB-A nrPDB 355 3e-98 4FXS-A nrPDB 335 3e-92 1ZFJ-A nrPDB 323 1e-88 4DQW-A nrPDB 310 1e-84 2CU0-A nrPDB 263 1e-70 5UQG-A nrPDB 224 7e-59 4MJM-A nrPDB 213 1e-55 1AK5-A nrPDB 199 3e-51 4FEZ-A nrPDB 198 6e-51 3FFS-A nrPDB 192 4e-49 4QJ1-A nrPDB 186 2e-47 1EEP-A nrPDB 181 5e-46 5AHL-A nrPDB 175 4e-44 5UPU-A nrPDB 165 5e-41 2C6Q-A nrPDB 121 9e-28 2BWG-A nrPDB 120 1e-27 3R2G-A nrPDB 114 1e-25 1YPF-A nrPDB 110 1e-24 6BFG-A nrPDB 42 5e-04 4N6F-A nrPDB 42 5e-04 2A85-A nrPDB 42 6e-04 2GJN-A nrPDB 39 0.006 5ZBN-A nrPDB 34 0.12 1AL8-A nrPDB 34 0.17 2GGG-A nrPDB 33 0.32 1P0K-A nrPDB 33 0.33 2J6X-A nrPDB 33 0.35 2CDH-0 nrPDB 33 0.40 1KA9-F nrPDB 33 0.44 4Q4K-A nrPDB 32 0.54 4S2R-P nrPDB 31 1.4 5ZKN-A nrPDB 31 1.5 3EOD-A nrPDB 31 1.5 6QVC-B nrPDB 30 2.1 4B5T-A nrPDB 30 2.4 2V5J-A nrPDB 30 2.5 6OD1-A nrPDB 30 2.6 6DVI-A nrPDB 30 3.2 2RDU-A nrPDB 30 3.4 4UTT-A nrPDB 30 3.7 2Z6J-A nrPDB 30 3.7 5LSM-A nrPDB 29 3.8 4MDT-A nrPDB 29 5.0 5GVH-A nrPDB 29 5.2 3SGZ-A nrPDB 29 6.1 3NZK-A nrPDB 28 7.5 >6I0M-A nrPDB Length = 517 Score = 1055 bits (2727), Expect = 0.0, Method: Compositional matrix adjust. Identities = 514/514 (100%), Positives = 514/514 (100%) Query: 1 MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKIT 60 MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKIT Sbjct: 4 MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKIT 63 Query: 61 LKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVV 120 LKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVV Sbjct: 64 LKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVV 123 Query: 121 LSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMT 180 LSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMT Sbjct: 124 LSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMT 183 Query: 181 KREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDA 240 KREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDA Sbjct: 184 KREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDA 243 Query: 241 KKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVI 300 KKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVI Sbjct: 244 KKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVI 303 Query: 301 GGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVP 360 GGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVP Sbjct: 304 GGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVP 363 Query: 361 VIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM 420 VIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM Sbjct: 364 VIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM 423 Query: 421 DKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVR 480 DKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVR Sbjct: 424 DKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVR 483 Query: 481 AMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF 514 AMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF Sbjct: 484 AMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF 517 >1JCN-A nrPDB Length = 514 Score = 903 bits (2333), Expect = 0.0, Method: Compositional matrix adjust. Identities = 430/514 (83%), Positives = 470/514 (91%) Query: 1 MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKIT 60 MADYLISGGT YVP+DGLTAQQLF D LTYNDFLILPG+IDF AD+VDLTSALT+KIT Sbjct: 1 MADYLISGGTGYVPEDGLTAQQLFASADDLTYNDFLILPGFIDFIADEVDLTSALTRKIT 60 Query: 61 LKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVV 120 LKTPL+SSPMDTVTEA MAIAMAL GGIGFIHHNCTPEFQANEVRKVK +EQGFITDPVV Sbjct: 61 LKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKNFEQGFITDPVV 120 Query: 121 LSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMT 180 LSP V DV EAK RHGF GIPIT+TG MGS+LVGI++SRDIDFL E++H L E+MT Sbjct: 121 LSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMT 180 Query: 181 KREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDA 240 R +LVVAPAG+TLKEANEILQRSKKGKLPIVN+ DELVAIIARTDLKKNRDYPLASKD+ Sbjct: 181 PRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDS 240 Query: 241 KKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVI 300 +KQLLCGAA+GT EDDKYRLDLL QAGVDV+VLDSSQGNS++QI M+ YIK KYP+LQVI Sbjct: 241 QKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVI 300 Query: 301 GGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVP 360 GGNVVTAAQAKNLIDAGVD LRVGMG GSICITQEV+ACGRPQ TAVYKV+EYARRFGVP Sbjct: 301 GGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVP 360 Query: 361 VIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM 420 +IADGGIQ VGH+ KALALGASTVMMGSLLAATTEAPGEYFFSDG+RLKKYRGMGSLDAM Sbjct: 361 IIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAM 420 Query: 421 DKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVR 480 +K SSQ RYFSE DK+K+AQGVSG++QDKGSI KFVPYLIAGIQH CQDIGA+SL+ +R Sbjct: 421 EKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLR 480 Query: 481 AMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF 514 +MMYSGELKFEKRT SAQ+EGGVH LHSYEKRL+ Sbjct: 481 SMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY 514 >4Z87-A nrPDB Length = 525 Score = 655 bits (1689), Expect = 0.0, Method: Compositional matrix adjust. Identities = 326/511 (63%), Positives = 396/511 (77%), Gaps = 11/511 (2%) Query: 11 SYVPDDGLTAQQLFNCGD--GLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSS 68 +Y DGL+ +QL + GLTYNDFL+LPG IDF + +V L+S LTKKITL P VSS Sbjct: 18 TYAEKDGLSVEQLMDSKTRGGLTYNDFLVLPGKIDFPSSEVVLSSRLTKKITLNAPFVSS 77 Query: 69 PMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVR 128 PMDTVTEA MAI MAL GGIG IHHNCT E QA VR+VKKYE GFI PVV+ P V Sbjct: 78 PMDTVTEADMAIHMALLGGIGIIHHNCTAEEQAEMVRRVKKYENGFINAPVVVGPDATVA 137 Query: 129 DVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVA 188 DV K GF G P+TD G+ +L GII+SRDI F+++E + EIMTK D++ Sbjct: 138 DVRRMKNEFGFAGFPVTDDGKPTGKLQGIITSRDIQFVEDET--LLVSEIMTK--DVITG 193 Query: 189 PAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDA-KKQLLCG 247 GI L+EAN+IL+ +KKGKLPIV+E LV++++RTDL KN+ YPLASK A KQLLCG Sbjct: 194 KQGINLEEANQILKNTKKGKLPIVDEAGCLVSMLSRTDLMKNQSYPLASKSADTKQLLCG 253 Query: 248 AAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTA 307 AAIGT + D+ RL +L +AG+DVVVLDSSQGNS+FQINMIK+IK+ +P+LQVI GNVVT Sbjct: 254 AAIGTIDADRQRLAMLVEAGLDVVVLDSSQGNSVFQINMIKWIKETFPDLQVIAGNVVTR 313 Query: 308 AQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGI 367 QA +LI AG D LR+GMGSGSICITQEV+ACGRPQ TAVY V+++A +FGVP IADGG+ Sbjct: 314 EQAASLIHAGADGLRIGMGSGSICITQEVMACGRPQGTAVYNVTQFANQFGVPCIADGGV 373 Query: 368 QNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKH---- 423 QN+GHI KA+ALGASTVMMG +LA TTE+PGEYFF DG RLK YRGMGS+DAM K Sbjct: 374 QNIGHITKAIALGASTVMMGGMLAGTTESPGEYFFRDGKRLKTYRGMGSIDAMQKTDVKG 433 Query: 424 LSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMM 483 ++ +RYFSE+DK+ VAQGV+G+V DKGSI K++PYL G+QHSCQDIG +SL + R + Sbjct: 434 NAATSRYFSESDKVLVAQGVTGSVIDKGSIKKYIPYLYNGLQHSCQDIGVRSLVEFREKV 493 Query: 484 YSGELKFEKRTSSAQVEGGVHSLHSYEKRLF 514 SG ++FE RT SAQ+EGGVH+LHSYEKRLF Sbjct: 494 DSGSVRFEFRTPSAQLEGGVHNLHSYEKRLF 524 >4AF0-B nrPDB Length = 556 Score = 613 bits (1581), Expect = e-176, Method: Compositional matrix adjust. Identities = 309/521 (59%), Positives = 384/521 (73%), Gaps = 23/521 (4%) Query: 12 YVPDDGLTAQQLFNC--GDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSP 69 Y DGL+ Q+L + GLTYNDFL+LPG+I+F A V L S TK I L TP +SSP Sbjct: 40 YPRGDGLSLQELMDSRKNGGLTYNDFLVLPGHINFPASDVSLQSKATKNIVLNTPFLSSP 99 Query: 70 MDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRD 129 MDTVTE MAIA+AL GG+G IHHNC+ E QA VR+VKKYE GFITDP+ L P V D Sbjct: 100 MDTVTEDRMAIALALHGGLGIIHHNCSAEEQAAMVRRVKKYENGFITDPLCLGPDATVGD 159 Query: 130 VFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAP 189 V E KA+ GFCG+PIT+TG S+L+GI++ RD+ F ++ + ++ +MT ++V Sbjct: 160 VLEIKAKFGFCGVPITETGEPDSKLLGIVTGRDVQF---QDAETPIKSVMTT--EVVTGS 214 Query: 190 AGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASK-DAKKQLLCGA 248 + ITL++AN +L+ +KKGKLPIV+ + LV+++AR+DL KN++YP ASK KQL CGA Sbjct: 215 SPITLEKANSLLRETKKGKLPIVDSNGHLVSLVARSDLLKNQNYPYASKVPESKQLYCGA 274 Query: 249 AIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAA 308 AIGT DK RL LLA+AG+DVVVLDSSQGNS++QI IK+IK YP + VI GNVVT Sbjct: 275 AIGTRPGDKDRLKLLAEAGLDVVVLDSSQGNSVYQIEFIKWIKQTYPKIDVIAGNVVTRE 334 Query: 309 QAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQ 368 QA LI AG D LR+GMGSGSICITQEV+A GRPQ TAVY V+E+A RFG+P IADGGI Sbjct: 335 QAAQLIAAGADGLRIGMGSGSICITQEVMAVGRPQGTAVYAVAEFASRFGIPCIADGGIG 394 Query: 369 NVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHL---- 424 N+GHIAKALALGAS VMMG LLA TTE+PGEYF+ +G R+K YRGMGS++AM+ Sbjct: 395 NIGHIAKALALGASAVMMGGLLAGTTESPGEYFYHEGKRVKVYRGMGSIEAMEHTQRGSA 454 Query: 425 -----------SSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGA 473 ++ RYFSEAD +KVAQGVSG V DKGSI+KFVPYL G+QHS QD G Sbjct: 455 SGKRSILGLDNAATARYFSEADAVKVAQGVSGDVADKGSINKFVPYLFTGLQHSLQDAGI 514 Query: 474 KSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF 514 KS++++ + SG L+FE RT+SAQ+EGGVH L+SY KRLF Sbjct: 515 KSVSELHSCARSGSLRFELRTASAQLEGGVHGLNSYTKRLF 555 >4XTI-A nrPDB Length = 413 Score = 417 bits (1071), Expect = e-117, Method: Compositional matrix adjust. Identities = 216/365 (59%), Positives = 272/365 (74%), Gaps = 16/365 (4%) Query: 163 IDFLKEEEHDCFLEEIMTKREDL---VVAPAGITLKEANEILQRSKKGKLPIVNED---D 216 IDF E L +TK+ L V+ T+ EA+ + + G + I++ + + Sbjct: 51 IDFPSSE---VVLSSRLTKKITLNAPFVSSPMDTVTEADMAIHMALLGGIGIIHHNCTAE 107 Query: 217 ELVAIIARTDLKKN--RDYPLASKDA-KKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVL 273 E ++ R +N +D PLASK A KQLLCGAAIGT + D+ RL +L +AG+DVVVL Sbjct: 108 EQAEMVRRVKKYENGSQDGPLASKSADTKQLLCGAAIGTIDADRQRLAMLVEAGLDVVVL 167 Query: 274 DSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICIT 333 DSSQGNS+FQINMIK+IK+ +P+LQVI GNVVT QA +LI AG D LR+GMGSGSICIT Sbjct: 168 DSSQGNSVFQINMIKWIKETFPDLQVIAGNVVTREQAASLIHAGADGLRIGMGSGSICIT 227 Query: 334 QEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAAT 393 QEV+ACGRPQ TAVY V+++A +FGVP IADGG+QN+GHI KA+ALGASTVMMG +LA T Sbjct: 228 QEVMACGRPQGTAVYNVTQFANQFGVPCIADGGVQNIGHITKAIALGASTVMMGGMLAGT 287 Query: 394 TEAPGEYFFSDGIRLKKYRGMGSLDAMDKH----LSSQNRYFSEADKIKVAQGVSGAVQD 449 TE+PGEYFF DG RLK YRGMGS+DAM K ++ +RYFSE+DK+ VAQGV+G+V D Sbjct: 288 TESPGEYFFRDGKRLKTYRGMGSIDAMQKTDVKGNAATSRYFSESDKVLVAQGVTGSVID 347 Query: 450 KGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSY 509 KGSI K++PYL G+QHSCQDIG +SL + R + SG ++FE RT SAQ+EGGVH+LHSY Sbjct: 348 KGSIKKYIPYLYNGLQHSCQDIGVRSLVEFREKVDSGSVRFEFRTPSAQLEGGVHNLHSY 407 Query: 510 EKRLF 514 EKRLF Sbjct: 408 EKRLF 412 Score = 139 bits (351), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 71/117 (60%), Positives = 81/117 (69%), Gaps = 2/117 (1%) Query: 11 SYVPDDGLTAQQLFNCGD--GLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSS 68 +Y DGL+ +QL + GLTYNDFL+LPG IDF + +V L+S LTKKITL P VSS Sbjct: 18 TYAEKDGLSVEQLMDSKTRGGLTYNDFLVLPGKIDFPSSEVVLSSRLTKKITLNAPFVSS 77 Query: 69 PMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKD 125 PMDTVTEA MAI MAL GGIG IHHNCT E QA VR+VKKYE G P+ D Sbjct: 78 PMDTVTEADMAIHMALLGGIGIIHHNCTAEEQAEMVRRVKKYENGSQDGPLASKSAD 134 >1VRD-A nrPDB Length = 494 Score = 361 bits (926), Expect = e-100, Method: Compositional matrix adjust. Identities = 193/453 (42%), Positives = 289/453 (63%), Gaps = 7/453 (1%) Query: 28 DGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGG 87 + LT++D L++P Y + V + + LT++I + PLVS+ MDTVTEA +A A+A GG Sbjct: 15 EALTFDDVLLVPQYSEVLPKDVKIDTRLTRQIRINIPLVSAAMDTVTEAALAKALAREGG 74 Query: 88 IGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDT 147 IG IH N TP+ QA +V VKK E G I DP+ ++P V++ + A + G+P+ D Sbjct: 75 IGIIHKNLTPDEQARQVSIVKKTENGIIYDPITVTPDMTVKEAIDLMAEYKIGGLPVVDE 134 Query: 148 GRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKG 207 RLVG++++RD+ F E+ ++++MT RE L+VAP I+L++A EIL + + Sbjct: 135 E---GRLVGLLTNRDVRF--EKNLSKKIKDLMTPREKLIVAPPDISLEKAKEILHQHRIE 189 Query: 208 KLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAG 267 KLP+V++D++LV +I D+ ++P A++D K +LL GAA+GT + R++ L +AG Sbjct: 190 KLPLVSKDNKLVGLITIKDIMSVIEHPNAARDEKGRLLVGAAVGTSPETMERVEKLVKAG 249 Query: 268 VDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGS 327 VDV+V+D++ G+S I ++ IK YP+L V+ GNV T + LI AG DA++VG+G Sbjct: 250 VDVIVIDTAHGHSRRVIETLEMIKADYPDLPVVAGNVATPEGTEALIKAGADAVKVGVGP 309 Query: 328 GSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMG 387 GSIC T+ V G PQ TAV + SE AR++ VP+IADGGI+ G I KALA GA +VM+G Sbjct: 310 GSICTTRVVAGVGVPQLTAVMECSEVARKYDVPIIADGGIRYSGDIVKALAAGAESVMVG 369 Query: 388 SLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAV 447 S+ A T EAPGE G + K YRGMGSL AM S +RY E + V +G+ G V Sbjct: 370 SIFAGTEEAPGETILYQGRKYKAYRGMGSLGAMRS--GSADRYGQEGENKFVPEGIEGMV 427 Query: 448 QDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVR 480 KG++ V L+ G++ IGA+++ +++ Sbjct: 428 PYKGTVKDVVHQLVGGLRSGMGYIGARTIKELQ 460 >3TSB-A nrPDB Length = 511 Score = 355 bits (911), Expect = 3e-98, Method: Compositional matrix adjust. Identities = 194/454 (42%), Positives = 287/454 (63%), Gaps = 8/454 (1%) Query: 28 DGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGG 87 +GLT++D L++P D +V + + L++ + L PL+S+ MDTVTEA MAIAMA GG Sbjct: 33 EGLTFDDVLLVPAKSDVLPREVSVKTVLSESLQLNIPLISAGMDTVTEADMAIAMARQGG 92 Query: 88 IGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDT 147 +G IH N + E QA +V KVK+ E G I+DP L+P+ +V D ++ G+P+ + Sbjct: 93 LGIIHKNMSIEQQAEQVDKVKRSESGVISDPFFLTPEHQVYDAEHLMGKYRISGVPVVNN 152 Query: 148 GRMGSR-LVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKK 206 + R LVGII++RD+ F+ +++ + ++MTK E L+ AP G TL EA +ILQ+ K Sbjct: 153 --LDERKLVGIITNRDMRFI--QDYSIKISDVMTK-EQLITAPVGTTLSEAEKILQKYKI 207 Query: 207 GKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQA 266 KLP+V+ + L +I D++K ++P ++KD + +LL GAA+G D R+D L +A Sbjct: 208 EKLPLVDNNGVLQGLITIKDIEKVIEFPNSAKDKQGRLLVGAAVGVTADAMTRIDALVKA 267 Query: 267 GVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMG 326 VD +VLD++ G+S I+ +K ++ KYP+L +I GNV TA K LI+AG + ++VG+G Sbjct: 268 SVDAIVLDTAHGHSQGVIDKVKEVRAKYPSLNIIAGNVATAEATKALIEAGANVVKVGIG 327 Query: 327 SGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMM 386 GSIC T+ V G PQ TAVY + AR+ G+PVIADGGI+ G + KALA GA VM+ Sbjct: 328 PGSICTTRVVAGVGVPQLTAVYDCATEARKHGIPVIADGGIKYSGDMVKALAAGAHVVML 387 Query: 387 GSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGA 446 GS+ A E+PGE G + K YRGMGS+ AM+K S++RYF E +K V +G+ G Sbjct: 388 GSMFAGVAESPGETEIYQGRQFKVYRGMGSVGAMEK--GSKDRYFQEGNKKLVPEGIEGR 445 Query: 447 VQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVR 480 V KG + V L+ G++ GA+ L +R Sbjct: 446 VPYKGPLADTVHQLVGGLRAGMGYCGAQDLEFLR 479 >4FXS-A nrPDB Length = 496 Score = 335 bits (858), Expect = 3e-92, Method: Compositional matrix adjust. Identities = 188/457 (41%), Positives = 276/457 (60%), Gaps = 13/457 (2%) Query: 28 DGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGG 87 + LT++D L++P + + DL + LTK I L P+VS+ MDTVTEA +AIA+A GG Sbjct: 9 EALTFDDVLLVPAHSTVLPNTADLRTRLTKNIALNIPMVSASMDTVTEARLAIALAQEGG 68 Query: 88 IGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDT 147 IGFIH N + E QA +V +VK +E G +T PV + P+ + DV E HGF G P+ Sbjct: 69 IGFIHKNMSIEQQAAQVHQVKIFEAGVVTHPVTVRPEQTIADVMELTHYHGFAGFPVVTE 128 Query: 148 GRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKG 207 + LVGII+ RD+ F+ + + +MT +E L G T E E + +++ Sbjct: 129 N---NELVGIITGRDVRFVTDLTKS--VAAVMTPKERLATVKEGATGAEVQEKMHKARVE 183 Query: 208 KLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAG 267 K+ +VN++ +L +I D K P A KD + +L GAA+G ++ R+ L +AG Sbjct: 184 KILVVNDEFQLKGMITAKDFHKAESKPNACKDEQGRLRVGAAVGAAPGNEERVKALVEAG 243 Query: 268 VDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGS 327 VDV+++DSS G+S + I+ + YP+L++IGGNV TA A+ LI+AGV A++VG+G Sbjct: 244 VDVLLIDSSHGHSEGVLQRIRETRAAYPHLEIIGGNVATAEGARALIEAGVSAVKVGIGP 303 Query: 328 GSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMG 387 GSIC T+ V G PQ TA+ + A +G+PVIADGGI+ G I+KA+A GAS VM+G Sbjct: 304 GSICTTRIVTGVGVPQITAIADAAGVANEYGIPVIADGGIRFSGDISKAIAAGASCVMVG 363 Query: 388 SLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYF---SEADKIKVAQGVS 444 S+ A T EAPGE G K YRGMGSL AM K S +RYF + ADK+ V +G+ Sbjct: 364 SMFAGTEEAPGEVILYQGRSYKAYRGMGSLGAMSK--GSSDRYFQTDNAADKL-VPEGIE 420 Query: 445 GAVQDKGSIHKFVPYLIAGIQHSCQDI-GAKSLTQVR 480 G + KG + + + + G++ SC + G+ ++ +R Sbjct: 421 GRIAYKGHLKEIIHQQMGGLR-SCMGLTGSATVEDLR 456 >1ZFJ-A nrPDB Length = 491 Score = 323 bits (828), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 184/455 (40%), Positives = 270/455 (59%), Gaps = 11/455 (2%) Query: 29 GLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGI 88 G T++D L++P ++VDL + L +TL P++++ MDTVT + MAIA+A GG+ Sbjct: 11 GYTFDDVLLIPAESHVLPNEVDLKTKLADNLTLNIPIITAAMDTVTGSKMAIAIARAGGL 70 Query: 89 GFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTG 148 G IH N + QA EVRKVK+ E G I DP L+P+ +V + E R+ G+PI +T Sbjct: 71 GVIHKNMSITEQAEEVRKVKRSENGVIIDPFFLTPEHKVSEAEELMQRYRISGVPIVET- 129 Query: 149 RMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGK 208 +LVGII++RD+ F+ + ++ + E MT E LV A G L+ A IL + K Sbjct: 130 LANRKLVGIITNRDMRFISD--YNAPISEHMTS-EHLVTAAVGTDLETAERILHEHRIEK 186 Query: 209 LPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGV 268 LP+V+ L +I D++K ++P A+KD +LL AA+G D R + L +AG Sbjct: 187 LPLVDNSGRLSGLITIKDIEKVIEFPHAAKDEFGRLLVAAAVGVTSDTFERAEALFEAGA 246 Query: 269 DVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSG 328 D +V+D++ G+S + I I+ +PN +I GN+ TA A+ L DAGVD ++VG+G G Sbjct: 247 DAIVIDTAHGHSAGVLRKIAEIRAHFPNRTLIAGNIATAEGARALYDAGVDVVKVGIGPG 306 Query: 329 SICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGS 388 SIC T+ V G PQ TA+Y + AR +G +IADGGI+ G I KALA G + VM+GS Sbjct: 307 SICTTRVVAGVGVPQVTAIYDAAAVAREYGKTIIADGGIKYSGDIVKALAAGGNAVMLGS 366 Query: 389 LLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYF----SEADKIKVAQGVS 444 + A T EAPGE G + K YRGMGS+ AM K S +RYF +EA+K+ V +G+ Sbjct: 367 MFAGTDEAPGETEIYQGRKYKTYRGMGSIAAMKK--GSSDRYFQGSVNEANKL-VPEGIE 423 Query: 445 GAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQV 479 G V KG+ V ++ GI+ +GA + ++ Sbjct: 424 GRVAYKGAASDIVFQMLGGIRSGMGYVGAGDIQEL 458 >4DQW-A nrPDB Length = 509 Score = 310 bits (794), Expect = 1e-84, Method: Compositional matrix adjust. Identities = 199/484 (41%), Positives = 289/484 (59%), Gaps = 16/484 (3%) Query: 28 DGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGG 87 + LT++D L++PGY + V L + LT+ I L PLVS+ MDTVTEA +AIAMA GG Sbjct: 27 EALTFDDVLLIPGYSEVLPKDVSLKTRLTRGIELNIPLVSAAMDTVTEARLAIAMAQEGG 86 Query: 88 IGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDT 147 IG IH N E QA EVRKVKK+E + DPV ++P ++ ++ + +GF G P+ + Sbjct: 87 IGIIHKNMGIEQQAAEVRKVKKHETAIVRDPVTVTPSTKIIELLQMAREYGFSGFPVVEQ 146 Query: 148 GRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKG 207 G LVGI++ RD+ +K D + IMT ++ LV A G L+E L ++ Sbjct: 147 GE----LVGIVTGRDLR-VKPNAGDT-VAAIMTPKDKLVTAREGTPLEEMKAKLYENRIE 200 Query: 208 KLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAG 267 K+ +V+E+ L ++ D++K + YPLASKD + +L GAA+GT D R+ L AG Sbjct: 201 KMLVVDENFYLRGLVTFRDIEKAKTYPLASKDEQGRLRVGAAVGTGADTGERVAALVAAG 260 Query: 268 VDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGS 327 VDVVV+D++ G+S I ++++K +P++QVIGGN+ TA AK L +AG DA++VG+G Sbjct: 261 VDVVVVDTAHGHSKGVIERVRWVKQTFPDVQVIGGNIATAEAAKALAEAGADAVKVGIGP 320 Query: 328 GSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMG 387 GSIC T+ V G PQ +A+ V+ GVP+IADGGI+ G +AKA+ GA VMMG Sbjct: 321 GSICTTRIVAGVGVPQISAIANVAAALEGTGVPLIADGGIRFSGDLAKAMVAGAYCVMMG 380 Query: 388 SLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSE----ADKIKVAQGV 443 S+ A T EAPGE G K YRGMGSL AM S +RYF + A+K+ V +G+ Sbjct: 381 SMFAGTEEAPGEIELFQGRSYKSYRGMGSLGAMSGSQGSSDRYFQDASAGAEKL-VPEGI 439 Query: 444 SGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGV 503 G V KG++ V L+ G++ + G+ + Q+R + +F + T + E V Sbjct: 440 EGRVPYKGALSAIVHQLMGGLRAAMGYTGSADIQQMRT-----QPQFVRITGAGMAESHV 494 Query: 504 HSLH 507 H + Sbjct: 495 HDVQ 498 >2CU0-A nrPDB Length = 486 Score = 263 bits (672), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 161/467 (34%), Positives = 267/467 (57%), Gaps = 20/467 (4%) Query: 17 GLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEA 76 G ++L G T++D L++P + VD+++ +T + L P++S+ MDTVTE Sbjct: 2 GKFVEKLEKAIKGYTFDDVLLIPQATEVEPKDVDVSTRITPNVKLNIPILSAAMDTVTEW 61 Query: 77 GMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKAR 136 MA+AMA GG+G IH N E Q +V++VK+ E+ + D + ++P + V + Sbjct: 62 EMAVAMAREGGLGVIHRNMGIEEQVEQVKRVKRAERLIVEDVITIAPDETVDFALFLMEK 121 Query: 137 HGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKE 196 HG G+P+ + ++VGII+ +DI ++E+MTK +++ P I ++E Sbjct: 122 HGIDGLPVVED----EKVVGIITKKDI----AAREGKLVKELMTK--EVITVPESIEVEE 171 Query: 197 ANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDD 256 A +I+ ++ +LP+V+E +LV +I +DL + Y A +D +LL AA+ D Sbjct: 172 ALKIMIENRIDRLPVVDERGKLVGLITMSDLVARKKYKNAVRDENGELLVAAAVSPF--D 229 Query: 257 KYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDA 316 R L +AGVDV+V+D++ +++ I +K ++ K + I GN+ +L A Sbjct: 230 IKRAIELDKAGVDVIVVDTAHAHNLKAIKSMKEMRQKV-DADFIVGNIANPKAVDDLTFA 288 Query: 317 GVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKA 376 DA++VG+G GSIC T+ V G PQ TAV V++ A+ +G+ VIADGGI+ G I KA Sbjct: 289 --DAVKVGIGPGSICTTRIVAGVGVPQITAVAMVADRAQEYGLYVIADGGIRYSGDIVKA 346 Query: 377 LALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEA-- 434 +A GA VM+G+LLA T EAPG+ +G + K+YRGMGSL AM K RY+ Sbjct: 347 IAAGADAVMLGNLLAGTKEAPGKEVIINGRKYKQYRGMGSLGAMMK--GGAERYYQGGYM 404 Query: 435 -DKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVR 480 + V +GV G V +G++ + + L+ G++ +GA+++ +++ Sbjct: 405 KTRKFVPEGVEGVVPYRGTVSEVLYQLVGGLKAGMGYVGARNIRELK 451 >5UQG-A nrPDB Length = 406 Score = 224 bits (571), Expect = 7e-59, Method: Compositional matrix adjust. Identities = 140/284 (49%), Positives = 184/284 (64%), Gaps = 13/284 (4%) Query: 226 DLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQIN 285 DLKK ++YP A+KD +L GAAIG + D R+D L +AGVDVVVLDS+ G+S I+ Sbjct: 119 DLKKRKEYPDANKDNFGRLRVGAAIGVGQMD--RVDALVEAGVDVVVLDSAHGHSKGIID 176 Query: 286 MIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQAT 345 +K IK KYPNL +I GN+ TAA AK L +AGVDA++VG+G GSIC T+ V G PQ + Sbjct: 177 TVKAIKAKYPNLDLIAGNIATAAAAKALCEAGVDAVKVGIGPGSICTTRIVSGVGVPQIS 236 Query: 346 AVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDG 405 A+ + E A +FGVPVIADGGI+ G IAKALA+GAS+VM+GSLLA T E+PGE F G Sbjct: 237 AIDECVEEANKFGVPVIADGGIKYSGDIAKALAVGASSVMIGSLLAGTDESPGELFTYQG 296 Query: 406 IRLKKYRGMGSLDAMDKHLSSQNRYFSEA---DKIKVAQGVSGAVQDKGSIHKFVPYLIA 462 + K YRGMGSL AM K S +RYF + DK+ V +G+ G V GSI V L+ Sbjct: 297 RQYKSYRGMGSLGAMQK--GSSDRYFQQGTAQDKL-VPEGIEGRVPYVGSIRSVVHQLLG 353 Query: 463 GIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSL 506 G++ S +GAK + + +F + T++ E VH + Sbjct: 354 GLRSSMGYVGAKDIED-----FQKRAEFVEITTAGLKESHVHDV 392 Score = 84.3 bits (207), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 43/88 (48%), Positives = 54/88 (61%) Query: 30 LTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIG 89 LT+ D L+ PGY + +V + + LTK ITL PL+S+ MDTVTE AI MA GG+G Sbjct: 32 LTFEDVLLRPGYSEVLPKEVKIHTKLTKNITLNMPLISAAMDTVTEHRAAIMMARLGGLG 91 Query: 90 FIHHNCTPEFQANEVRKVKKYEQGFITD 117 IH N Q EV++VKK E G I D Sbjct: 92 VIHKNMDIASQVREVKRVKKSESGGIKD 119 >4MJM-A nrPDB Length = 385 Score = 213 bits (543), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 122/300 (40%), Positives = 183/300 (61%), Gaps = 14/300 (4%) Query: 193 TLKEANEILQRSKKGKLPIVNED------DELVAIIART------DLKKNRDYPLASKDA 240 T+ EA+ + +++G L I++++ E V + R+ D++K ++P ++KD Sbjct: 56 TVTEADMAIAMARQGGLGIIHKNMSIEQQAEQVDKVKRSESGGIKDIEKVIEFPNSAKDK 115 Query: 241 KKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVI 300 + +LL GAA+G D R+D L +A VD +VLD++ G+S I+ +K ++ KYP+L +I Sbjct: 116 QGRLLVGAAVGVTADAMTRIDALVKASVDAIVLDTAHGHSQGVIDKVKEVRAKYPSLNII 175 Query: 301 GGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVP 360 GNV TA K LI+AG + ++VG+G GSIC T+ V G PQ TAVY + AR+ G+P Sbjct: 176 AGNVATAEATKALIEAGANVVKVGIGPGSICTTRVVAGVGVPQLTAVYDCATEARKHGIP 235 Query: 361 VIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM 420 VIADGGI+ G + KALA GA VM+GS+ A E+PGE G + K YRGMGS+ AM Sbjct: 236 VIADGGIKYSGDMVKALAAGAHVVMLGSMFAGVAESPGETEIYQGRQFKVYRGMGSVGAM 295 Query: 421 DKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVR 480 +K S++RYF E +K V +G+ G V KG + V L+ G++ GA+ L +R Sbjct: 296 EK--GSKDRYFQEGNKKLVPEGIEGRVPYKGPLADTVHQLVGGLRAGMGYCGAQDLEFLR 353 Score = 87.8 bits (216), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 43/90 (47%), Positives = 60/90 (66%) Query: 28 DGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGG 87 +GLT++D L++P D +V + + L++ + L PL+S+ MDTVTEA MAIAMA GG Sbjct: 12 EGLTFDDVLLVPAKSDVLPREVSVKTVLSESLQLNIPLISAGMDTVTEADMAIAMARQGG 71 Query: 88 IGFIHHNCTPEFQANEVRKVKKYEQGFITD 117 +G IH N + E QA +V KVK+ E G I D Sbjct: 72 LGIIHKNMSIEQQAEQVDKVKRSESGGIKD 101 >1AK5-A nrPDB Length = 503 Score = 199 bits (505), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 164/495 (33%), Positives = 255/495 (51%), Gaps = 33/495 (6%) Query: 31 TYNDFLILPGY--IDFTADQVDLTSALTK-------KITLKTPLVSSPMDTVTEAGMAIA 81 T+N++L++PG +D V+L++ L K +I LK PLVS+ M +V+ MAIA Sbjct: 11 TFNEYLLIPGLSTVDCIPSNVNLSTPLVKFQKGQQSEINLKIPLVSAIMQSVSGEKMAIA 70 Query: 82 MALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCG 141 +A GGI FI + + E QA V VK ++ GF+ + P DV R Sbjct: 71 LAREGGISFIFGSQSIESQAAMVHAVKNFKAGFVVSDSNVKPDQTFADVLAISQRTTHNT 130 Query: 142 IPITDTGRMGSRLVGIISSRD--IDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANE 199 + +TD G L+G+++ RD ID + E + ++MT LV A L EAN+ Sbjct: 131 VAVTDDGTPHGVLLGLVTQRDYPIDLTQTETK---VSDMMTPFSKLVTAHQDTKLSEANK 187 Query: 200 ILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYR 259 I+ K LPI+++D L I+ R D +++ D++K+ L GA I T D + R Sbjct: 188 IIWEKKLNALPIIDDDQHLRYIVFRKDYDRSQVCHNELVDSQKRYLVGAGINTR-DFRER 246 Query: 260 LDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPN-LQVIGGNVVTAAQAKNLIDAGV 318 + L +AG DV+ +DSS G S +Q I +I++KY + ++V GN+V + L DAG Sbjct: 247 VPALVEAGADVLCIDSSDGFSEWQKITIGWIREKYGDKVKVGAGNIVDGEGFRYLADAGA 306 Query: 319 DALRVGMGSGSICITQEVLACGRPQATAVYKV----SEYARRFG--VPVIADGGIQNVGH 372 D +++G+G GSICIT+E GR QATAV V ++Y G +PV +DGGI H Sbjct: 307 DFIKIGIGGGSICITREQKGIGRGQATAVIDVVAERNKYFEETGIYIPVCSDGGIVYDYH 366 Query: 373 IAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRY-F 431 + ALA+GA +M+G A E+P +G +K+Y G GS A + RY Sbjct: 367 MTLALAMGADFIMLGRYFARFEESPTRKVTINGSVMKEYWGEGSSRARN-----WQRYDL 421 Query: 432 SEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFE 491 K+ +GV V G + V + ++ + + GA ++ Q+++ + K Sbjct: 422 GGKQKLSFEEGVDSYVPYAGKLKDNVEASLNKVKSTMCNCGALTIPQLQS-----KAKIT 476 Query: 492 KRTSSAQVEGGVHSL 506 +S + VEGG H + Sbjct: 477 LVSSVSIVEGGAHDV 491 >4FEZ-A nrPDB Length = 388 Score = 198 bits (503), Expect = 6e-51, Method: Compositional matrix adjust. Identities = 111/258 (43%), Positives = 159/258 (61%), Gaps = 6/258 (2%) Query: 226 DLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQIN 285 D K P A KD + +L GAA+G ++ R+ L +AGVDV+++DSS G+S + Sbjct: 101 DFHKAESKPNACKDEQGRLRVGAAVGAAPGNEERVKALVEAGVDVLLIDSSHGHSEGVLQ 160 Query: 286 MIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQAT 345 I+ + YP+L++IGGNV TA A+ LI+AGV A++VG+G GSIC T+ V G PQ T Sbjct: 161 RIRETRAAYPHLEIIGGNVATAEGARALIEAGVSAVKVGIGPGSICTTRIVTGVGVPQIT 220 Query: 346 AVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDG 405 A+ + A +G+PVIADGGI+ G I+KA+A GAS VM+GS+ A T EAPGE G Sbjct: 221 AIADAAGVANEYGIPVIADGGIRFSGDISKAIAAGASCVMVGSMFAGTEEAPGEVILYQG 280 Query: 406 IRLKKYRGMGSLDAMDKHLSSQNRYF---SEADKIKVAQGVSGAVQDKGSIHKFVPYLIA 462 K YRGMGSL AM K S +RYF + ADK+ V +G+ G + KG + + + + Sbjct: 281 RSYKAYRGMGSLGAMSK--GSSDRYFQTDNAADKL-VPEGIEGRIAYKGHLKEIIHQQMG 337 Query: 463 GIQHSCQDIGAKSLTQVR 480 G++ G+ ++ +R Sbjct: 338 GLRSCMGLTGSATVEDLR 355 Score = 87.8 bits (216), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 43/90 (47%), Positives = 59/90 (65%) Query: 28 DGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGG 87 + LT++D L++P + + DL + LTK I L P+VS+ MDTVTEA +AIA+A GG Sbjct: 12 EALTFDDVLLVPAHSTVLPNTADLRTRLTKNIALNIPMVSASMDTVTEARLAIALAQEGG 71 Query: 88 IGFIHHNCTPEFQANEVRKVKKYEQGFITD 117 IGFIH N + E QA +V +VK +E G D Sbjct: 72 IGFIHKNMSIEQQAAQVHQVKIFESGGAKD 101 >3FFS-A nrPDB Length = 400 Score = 192 bits (487), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 125/291 (42%), Positives = 167/291 (57%), Gaps = 13/291 (4%) Query: 194 LKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRD---YPLASKDAKKQLLCGAAI 250 LK N I K P N D E D K N + Y + D K +L GAAI Sbjct: 85 LKVKNWISNLEKNESTPDQNLDKESTD---GKDTKSNNNIDAYSNENLDNKGRLRVGAAI 141 Query: 251 GTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQA 310 G +E + R LL +AGVDV+VLDS+ G+S+ I +K IK K N+ VI GNVVT Sbjct: 142 GVNEIE--RAKLLVEAGVDVIVLDSAHGHSLNIIRTLKEIKSKM-NIDVIVGNVVTEEAT 198 Query: 311 KNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNV 370 K LI+ G D ++VG+G GSIC T+ V G PQ TA+ K S A +FG+P+IADGGI+ Sbjct: 199 KELIENGADGIKVGIGPGSICTTRIVAGVGVPQITAIEKCSSVASKFGIPIIADGGIRYS 258 Query: 371 GHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRY 430 G I KALA+GAS+VM+GS+LA T E+PGE K YRGMGS+ AM S +RY Sbjct: 259 GDIGKALAVGASSVMIGSILAGTEESPGEKELIGDTVYKYYRGMGSVGAMKS--GSGDRY 316 Query: 431 FSE--ADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQV 479 F E + V +G+ G V+ KG + V L+ G++ +G+ S+ ++ Sbjct: 317 FQEKRPENKMVPEGIEGRVKYKGEMEGVVYQLVGGLRSCMGYLGSASIEEL 367 Score = 94.4 bits (233), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 45/86 (52%), Positives = 56/86 (65%) Query: 25 NCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMAL 84 N G GLT+ D L++P Y + +V L + LTK ++LK PL+SS MDTVTE MA+ MA Sbjct: 5 NIGKGLTFEDILLVPNYSEVLPREVSLETKLTKNVSLKIPLISSAMDTVTEHLMAVGMAR 64 Query: 85 TGGIGFIHHNCTPEFQANEVRKVKKY 110 GGIG IH N E Q NEV KVK + Sbjct: 65 LGGIGIIHKNMDMESQVNEVLKVKNW 90 >4QJ1-A nrPDB Length = 361 Score = 186 bits (472), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 110/238 (46%), Positives = 149/238 (62%), Gaps = 7/238 (2%) Query: 244 LLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGN 303 L GAAIG +E + R LL +AGVDV+VLDS+ G+S+ I +K IK K N+ VI GN Sbjct: 96 LRVGAAIGVNEIE--RAKLLVEAGVDVIVLDSAHGHSLNIIRTLKEIKSKM-NIDVIVGN 152 Query: 304 VVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIA 363 VVT K LI+ G D ++VG+G GSIC T+ V G PQ TA+ K S A +FG+P+IA Sbjct: 153 VVTEEATKELIENGADGIKVGIGPGSICTTRIVAGVGVPQITAIEKCSSVASKFGIPIIA 212 Query: 364 DGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKH 423 DGGI+ G I KALA+GAS+VM+GS+LA T E+PGE K YRGMGS+ AM Sbjct: 213 DGGIRYSGDIGKALAVGASSVMIGSILAGTEESPGEKELIGDTVYKYYRGMGSVGAMKS- 271 Query: 424 LSSQNRYFSE--ADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQV 479 S +RYF E + V +G+ G V+ KG + V L+ G++ +G+ S+ ++ Sbjct: 272 -GSGDRYFQEKRPENKMVPEGIEGRVKYKGEMEGVVYQLVGGLRSCMGYLGSASIEEL 328 Score = 92.8 bits (229), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 45/84 (53%), Positives = 55/84 (65%) Query: 25 NCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMAL 84 N G GLT+ D L++P Y + +V L + LTK ++LK PL+SS MDTVTE MA+ MA Sbjct: 8 NIGKGLTFEDILLVPNYSEVLPREVSLETKLTKNVSLKIPLISSAMDTVTEHLMAVGMAR 67 Query: 85 TGGIGFIHHNCTPEFQANEVRKVK 108 GGIG IH N E Q NEV KVK Sbjct: 68 LGGIGIIHKNMDMESQVNEVLKVK 91 >1EEP-A nrPDB Length = 404 Score = 181 bits (460), Expect = 5e-46, Method: Compositional matrix adjust. Identities = 112/295 (37%), Positives = 165/295 (55%), Gaps = 16/295 (5%) Query: 222 IARTDLKKN----RDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQ 277 + ++D KN D+P A KD +L GAA+ D R++ L +A VD++V+DS+ Sbjct: 116 LEKSDAYKNAEHKEDFPNACKDLNNKLRVGAAVSIDIDTIERVEELVKAHVDILVIDSAH 175 Query: 278 GNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVL 337 G+S I +IK IK KYPNL +I GN+VT A +LI G D L+VG+G GSIC T+ V Sbjct: 176 GHSTRIIELIKKIKTKYPNLDLIAGNIVTKEAALDLISVGADCLKVGIGPGSICTTRIVA 235 Query: 338 ACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAP 397 G PQ TA+ V E + +IADGGI+ G + KA+A GA +VM+G+L A T E+P Sbjct: 236 GVGVPQITAICDVYEACNNTNICIIADGGIRFSGDVVKAIAAGADSVMIGNLFAGTKESP 295 Query: 398 GEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYF----SEADKIKVAQGVSGAVQDKGSI 453 E +G + K Y GMGS+ AM + S++RYF +E K+ V +G+ G V G + Sbjct: 296 SEEIIYNGKKFKSYVGMGSISAMKR--GSKSRYFQLENNEPKKL-VPEGIEGMVPYSGKL 352 Query: 454 HKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHS 508 + L G+ +GA +++ ++ KF K + S+ E H + S Sbjct: 353 KDILTQLKGGLMSGMGYLGAATISDLKI-----NSKFVKISHSSLKESHPHDVFS 402 Score = 78.2 bits (191), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 39/84 (46%), Positives = 53/84 (63%) Query: 28 DGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGG 87 + LT++D ++P +V L + LTK I+L P +SS MDTVTE+ MAIA+A GG Sbjct: 8 EALTFDDVSLIPRKSSVLPSEVSLKTQLTKNISLNIPFLSSAMDTVTESQMAIAIAKEGG 67 Query: 88 IGFIHHNCTPEFQANEVRKVKKYE 111 IG IH N + E Q E+ KVK Y+ Sbjct: 68 IGIIHKNMSIEAQRKEIEKVKTYK 91 >5AHL-A nrPDB Length = 400 Score = 175 bits (444), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 132/349 (37%), Positives = 202/349 (57%), Gaps = 19/349 (5%) Query: 172 DCFLEEIMTKREDL---VVAPAGITLKEANEILQRSKKGKLPIVNEDDEL------VAII 222 D L+ +T+ +L +V+ A T+ EA + +++G + I++++ + V + Sbjct: 47 DVSLKTRLTRGIELNIPLVSAAMDTVTEARLAIAMAQEGGIGIIHKNMGIEQQAAEVRKV 106 Query: 223 ARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIF 282 + + K + YPLASKD + +L GAA+GT D R+ L AGVDVVV+D++ G+S Sbjct: 107 KKHETAKAKTYPLASKDEQGRLRVGAAVGTGADTGERVAALVAAGVDVVVVDTAHGHSKG 166 Query: 283 QINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRP 342 I ++++K +P++QVIGGN+ TA AK L +AG DA++VG+G GSIC T+ V G P Sbjct: 167 VIERVRWVKQTFPDVQVIGGNIATAEAAKALAEAGADAVKVGIGPGSICTTRIVAGVGVP 226 Query: 343 QATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFF 402 Q +A+ V+ GVP+IADGGI+ G +AKA+ GA VMMGS+ A T EAPGE Sbjct: 227 QISAIANVAAALEGTGVPLIADGGIRFSGDLAKAMVAGAYCVMMGSMFAGTEEAPGEIEL 286 Query: 403 SDGIRLKKYRGMGSLDAMDKHLSSQNRYFSE----ADKIKVAQGVSGAVQDKGSIHKFVP 458 G K YRGMGSL AM S +RYF + A+K+ V +G+ G V KG++ V Sbjct: 287 FQGRSYKSYRGMGSLGAMSGSQGSSDRYFQDASAGAEKL-VPEGIEGRVPYKGALSAIVH 345 Query: 459 YLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLH 507 L+ G++ + G+ + Q+R + +F + T + E VH + Sbjct: 346 QLMGGLRAAMGYTGSADIQQMRT-----QPQFVRITGAGMAESHVHDVQ 389 Score = 93.6 bits (231), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 47/84 (55%), Positives = 58/84 (69%) Query: 28 DGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGG 87 + LT++D L++PGY + V L + LT+ I L PLVS+ MDTVTEA +AIAMA GG Sbjct: 27 EALTFDDVLLIPGYSEVLPKDVSLKTRLTRGIELNIPLVSAAMDTVTEARLAIAMAQEGG 86 Query: 88 IGFIHHNCTPEFQANEVRKVKKYE 111 IG IH N E QA EVRKVKK+E Sbjct: 87 IGIIHKNMGIEQQAAEVRKVKKHE 110 >5UPU-A nrPDB Length = 407 Score = 165 bits (417), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 108/263 (41%), Positives = 159/263 (60%), Gaps = 17/263 (6%) Query: 230 NRDYPLASKDAKKQ-------LLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIF 282 +R+ P+A + + + LL GAA+G D R +L AGVDV+V+D++ ++ Sbjct: 110 HRNLPVAEQAGQVEMVKRSGGLLVGAAVGVGGDAWVRAMMLVDAGVDVLVVDTAHAHNRL 169 Query: 283 QINMIKYIKDKYPN-LQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGR 341 ++M+ +K + + ++V+GGNV T + A L+DAG DA++VG+G GSIC T+ V G Sbjct: 170 VLDMVGKLKSEVGDRVEVVGGNVATRSAAAALVDAGADAVKVGVGPGSICTTRVVAGVGA 229 Query: 342 PQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYF 401 PQ TA+ + R GVPVIADGG+Q G IAKALA GAST M+GSLLA T EAPGE Sbjct: 230 PQITAILEAVAACRPAGVPVIADGGLQYSGDIAKALAAGASTAMLGSLLAGTAEAPGELI 289 Query: 402 FSDGIRLKKYRGMGSLDAMDKHLS----SQNRYFSE----ADKIKVAQGVSGAVQDKGSI 453 F +G + K YRGMGSL AM S++RYF++ DK+ V +G+ G V +G + Sbjct: 290 FVNGKQYKSYRGMGSLGAMRGRGGATSYSKDRYFADDALSEDKL-VPEGIEGRVPFRGPL 348 Query: 454 HKFVPYLIAGIQHSCQDIGAKSL 476 + L G++ + G+ ++ Sbjct: 349 SSVIHQLTGGLRAAMGYTGSPTI 371 Score = 89.0 bits (219), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 51/108 (47%), Positives = 62/108 (57%), Gaps = 8/108 (7%) Query: 10 TSYVPDDGLTAQQLFNCGD--------GLTYNDFLILPGYIDFTADQVDLTSALTKKITL 61 + YV GLT + GD GLT++D L+LP D D +S LTKKI L Sbjct: 20 SPYVRMGGLTTDPVPTGGDDPHKVAMLGLTFDDVLLLPAASDVVPATADTSSQLTKKIRL 79 Query: 62 KTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKK 109 K PLVSS MDTVTE+ MAIAMA GG+G +H N QA +V VK+ Sbjct: 80 KVPLVSSAMDTVTESRMAIAMARAGGMGVLHRNLPVAEQAGQVEMVKR 127 >2C6Q-A nrPDB Length = 351 Score = 121 bits (303), Expect = 9e-28, Method: Compositional matrix adjust. Identities = 74/262 (28%), Positives = 131/262 (50%), Gaps = 7/262 (2%) Query: 218 LVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQ 277 A+ L + +++ + D + L + G+ + ++ L A V + LD + Sbjct: 83 FTAVHKHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICLDVAN 142 Query: 278 GNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVL 337 G S + +K ++ ++P ++ GNVVT + LI +G D ++VG+G GS+C T++ Sbjct: 143 GYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKT 202 Query: 338 ACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAP 397 G PQ +AV + ++ A +I+DGG G +AKA GA VM+G +LA +E+ Sbjct: 203 GVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESG 262 Query: 398 GEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFV 457 GE DG + K + GM S AM K+ Y + ++G + V KG + + Sbjct: 263 GELIERDGKKYKLFYGMSSEMAMKKYAGGVAEY-------RASEGKTVEVPFKGDVEHTI 315 Query: 458 PYLIAGIQHSCQDIGAKSLTQV 479 ++ GI+ +C +GA L ++ Sbjct: 316 RDILGGIRSTCTYVGAAKLKEL 337 >2BWG-A nrPDB Length = 367 Score = 120 bits (302), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 74/269 (27%), Positives = 131/269 (48%), Gaps = 7/269 (2%) Query: 211 IVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDV 270 ++++ AI L + + + + + + G ++ +K L A V Sbjct: 88 VMSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKF 147 Query: 271 VVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSI 330 + LD + G S + +K ++ K+P ++ GNVVT + LI +G D ++VG+G GS+ Sbjct: 148 ICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSV 207 Query: 331 CITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLL 390 C T+ G PQ +AV + ++ A +I+DGG G +AKA GA VM+G + Sbjct: 208 CTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMF 267 Query: 391 AATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDK 450 + TE GE +G +LK + GM S AM+KH Y + ++G + V K Sbjct: 268 SGHTECAGEVIERNGRKLKLFYGMSSDTAMNKHAGGVAEY-------RASEGKTVEVPYK 320 Query: 451 GSIHKFVPYLIAGIQHSCQDIGAKSLTQV 479 G + + ++ G++ +C +GA L ++ Sbjct: 321 GDVENTILDILGGLRSTCTYVGAAKLKEL 349 >3R2G-A nrPDB Length = 361 Score = 114 bits (285), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 78/267 (29%), Positives = 132/267 (49%), Gaps = 17/267 (6%) Query: 249 AIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAA 308 ++G E++ R + L AG D +D + ++ + +K ++ + ++ GNV T A Sbjct: 94 SVGCTENELQRAEALRDAGADFFCVDVAHAHAKYVGKTLKSLRQLLGSRCIMAGNVATYA 153 Query: 309 QAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQ 368 A L G D ++ G+G GS+C T+ G P T + S R ++ADGGI+ Sbjct: 154 GADYLASCGADIIKAGIGGGSVCSTRIKTGFGVPMLTCIQDCSRADR----SIVADGGIK 209 Query: 369 NVGHIAKALALGASTVMMGSLLAATTEAPGEYFFS-DGIRLKKYRGMGSLDAMDKHLSSQ 427 G I KALA GA VM+G +LA + PGE F DG ++K+YRGM S +A + L Sbjct: 210 TSGDIVKALAFGADFVMIGGMLAGSAPTPGEVFQKDDGSKVKRYRGMASREAQEAFLGQM 269 Query: 428 NRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGE 487 + + K A+GV+ V K + + +I G++ GA S+++++ + Sbjct: 270 HEW-------KTAEGVATEVPFKENPDGIIADIIGGLRSGLTYAGADSISELQR-----K 317 Query: 488 LKFEKRTSSAQVEGGVHSLHSYEKRLF 514 L + T + ++E H L + L+ Sbjct: 318 LNYVIVTQAGRIESLPHKLLEGAENLY 344 Score = 52.0 bits (123), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 28/81 (34%), Positives = 47/81 (58%), Gaps = 2/81 (2%) Query: 30 LTYNDFLILPGYIDFTADQVDLTSALTK--KITLKTPLVSSPMDTVTEAGMAIAMALTGG 87 +T++D L++P Y + +V T++ + K+TL P++S+ MDT+TE+ MA M G Sbjct: 8 ITFDDVLLVPSYNHHESRRVVETTSTDRLGKLTLNLPVISANMDTITESNMANFMHSKGA 67 Query: 88 IGFIHHNCTPEFQANEVRKVK 108 +G +H T E E +K K Sbjct: 68 MGALHRFMTIEENIQEFKKCK 88 >1YPF-A nrPDB Length = 336 Score = 110 bits (275), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 80/245 (32%), Positives = 122/245 (49%), Gaps = 21/245 (8%) Query: 244 LLCGAAIGTHEDDKYRLDLLAQAGV--DVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIG 301 L+ ++G ED+ + LA + + + +D + G+S INMI++IK P VI Sbjct: 95 LIASISVGVKEDEYEFVQQLAAEHLTPEYITIDIAHGHSNAVINMIQHIKKHLPESFVIA 154 Query: 302 GNVVTAAQAKNLIDAGVDALRVGMGSGSICIT--QEVLACGRPQATAVYKVSEYARRFGV 359 GNV T + L +AG DA +VG+G G +CIT + G Q A+ ++ A + Sbjct: 155 GNVGTPEAVRELENAGADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAASK--- 211 Query: 360 PVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDA 419 P+IADGGI+ G +AK++ GA+ VM+GSL A E+PGE DG K+Y G S Sbjct: 212 PIIADGGIRTNGDVAKSIRFGATMVMIGSLFAGHEESPGETIEKDGKLYKEYFGSAS--- 268 Query: 420 MDKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQV 479 F + +K K +G V+ KGS+ + + +Q S G L + Sbjct: 269 ----------EFQKGEK-KNVEGKKMFVEHKGSLEDTLIEMEQDLQSSISYAGGTKLDSI 317 Query: 480 RAMMY 484 R + Y Sbjct: 318 RTVDY 322 >6BFG-A nrPDB Length = 399 Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 10/127 (7%) Query: 273 LDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICI 332 L S Q ++ F +++++D +P+ ++ G +++A A I G D + + G Sbjct: 222 LMSRQMDASFNWEALRWLRDLWPHKLLVKG-LLSAEDADRCIAEGADGVILSNHGG---- 276 Query: 333 TQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAA 392 L C + + +++ + G PV+ D G + I KALALGA V++G Sbjct: 277 --RQLDCA---ISPMEVLAQSVAKTGKPVLIDSGFRRGSDIVKALALGAEAVLLGRATLY 331 Query: 393 TTEAPGE 399 A GE Sbjct: 332 GLAARGE 338 >4N6F-A nrPDB Length = 256 Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 30/83 (36%), Positives = 45/83 (54%), Gaps = 10/83 (12%) Query: 308 AQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGI 367 A A+ L +AG ALRV M S +A GR A + E + G+PV+ +GGI Sbjct: 148 ATARALEEAGCAALRV-MASP--------VASGRGIANPA-AIRELIEQIGIPVVVEGGI 197 Query: 368 QNVGHIAKALALGASTVMMGSLL 390 + H+A+A+ LGAS ++ + L Sbjct: 198 GSARHVAEAMELGASATLVNTAL 220 >2A85-A nrPDB Length = 380 Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 10/127 (7%) Query: 273 LDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICI 332 L S Q ++ F +++++D +P+ ++ G +++A A I G D + + G Sbjct: 203 LMSRQMDASFNWEALRWLRDLWPHKLLVKG-LLSAEDADRCIAEGADGVILSNHGG---- 257 Query: 333 TQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAA 392 L C + + +++ + G PV+ D G + I KALALGA V++G Sbjct: 258 --RQLDCA---ISPMEVLAQSVAKTGKPVLIDSGFRRGSDIVKALALGAEAVLLGRATLY 312 Query: 393 TTEAPGE 399 A GE Sbjct: 313 GLAARGE 319 >2GJN-A nrPDB Length = 328 Score = 38.9 bits (89), Expect = 0.006, Method: Compositional matrix adjust. Identities = 28/81 (34%), Positives = 36/81 (44%), Gaps = 3/81 (3%) Query: 354 ARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRG 413 A R VP+IA GG + + ALALGA + MG+ AT E P IR R Sbjct: 168 ANRLRVPIIASGGFADGRGLVAALALGADAINMGTRFLATRECPIHPAVKAAIRAADER- 226 Query: 414 MGSLDAMDKHLSSQNRYFSEA 434 S D + + L + R A Sbjct: 227 --STDLIMRSLRNTARVARNA 245 >5ZBN-A nrPDB Length = 371 Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust. Identities = 17/41 (41%), Positives = 25/41 (60%) Query: 359 VPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGE 399 +PV DGG++ + KALALGAS + +G + + A GE Sbjct: 281 IPVFLDGGVRRGTDVFKALALGASGIFIGRPVVFSLAAEGE 321 >1AL8-A nrPDB Length = 359 Score = 33.9 bits (76), Expect = 0.17, Method: Compositional matrix adjust. Identities = 17/41 (41%), Positives = 25/41 (60%) Query: 359 VPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGE 399 +PV DGG++ + KALALGA+ V +G + + A GE Sbjct: 280 IPVFLDGGVRRGTDVFKALALGAAGVFIGRPVVFSLAAEGE 320 >2GGG-A nrPDB Length = 375 Score = 33.1 bits (74), Expect = 0.32, Method: Compositional matrix adjust. Identities = 36/148 (24%), Positives = 67/148 (45%), Gaps = 18/148 (12%) Query: 241 KKQLLCGAAIGTHEDDKYRLDLL---AQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNL 297 K+Q+ G ++G D++ +DL+ + G + L G + + ++ ++ +P++ Sbjct: 134 KEQVEVGVSLGIQADEQATVDLVRRHVEQGYRRIKLKIKPG---WDVQPVRATREAFPDI 190 Query: 298 QVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRF 357 ++ V A A L DAG LR + + ++ LA + +E ARR Sbjct: 191 RL----TVDANSAYTLADAG--RLR-QLDEYDLTYIEQPLAW-----DDLVDHAELARRI 238 Query: 358 GVPVIADGGIQNVGHIAKALALGASTVM 385 P+ D + + KALALGA V+ Sbjct: 239 RTPLCLDESVASASDARKALALGAGGVI 266 >1P0K-A nrPDB Length = 349 Score = 33.1 bits (74), Expect = 0.33, Method: Compositional matrix adjust. Identities = 23/49 (46%), Positives = 32/49 (65%), Gaps = 2/49 (4%) Query: 361 VIADGGIQNVGHIAKALALGAS-TVMMGSLLAATTEAPGEYFFSDGIRL 408 +IA GG+Q+ +AKA+ALGAS T M G L A T++ GE + I+L Sbjct: 254 MIASGGLQDALDVAKAIALGASCTGMAGHFLKALTDS-GEEGLLEEIQL 301 >2J6X-A nrPDB Length = 374 Score = 32.7 bits (73), Expect = 0.35, Method: Compositional matrix adjust. Identities = 14/29 (48%), Positives = 20/29 (68%) Query: 359 VPVIADGGIQNVGHIAKALALGASTVMMG 387 VP++ D G++ H+AKALA GA V +G Sbjct: 291 VPIVFDSGVRRGEHVAKALASGADVVALG 319 >2CDH-0 nrPDB Length = 226 Score = 32.7 bits (73), Expect = 0.40, Method: Compositional matrix adjust. Identities = 17/41 (41%), Positives = 25/41 (60%) Query: 359 VPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGE 399 +PV DGG++ + KALALGA+ V +G + + A GE Sbjct: 164 IPVFLDGGVRRGTDVFKALALGAAGVFIGRPVVFSLAAEGE 204 >1KA9-F nrPDB Length = 252 Score = 32.7 bits (73), Expect = 0.44, Method: Compositional matrix adjust. Identities = 36/141 (25%), Positives = 57/141 (40%), Gaps = 14/141 (9%) Query: 238 KDAKKQLLCGA-AIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPN 296 +DA+K LL GA + + R +L+ + L G + + + +P Sbjct: 88 EDARKLLLSGADKVSVNSAAVRRPELIRE-------LADHFGAQAVVLAIDARWRGDFPE 140 Query: 297 LQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARR 356 + V GG V T A GV+ +G+G I +T + G + + A Sbjct: 141 VHVAGGRVPTGLHAVEWAVKGVE-----LGAGEILLTS-MDRDGTKEGYDLRLTRMVAEA 194 Query: 357 FGVPVIADGGIQNVGHIAKAL 377 GVPVIA GG + H +A Sbjct: 195 VGVPVIASGGAGRMEHFLEAF 215 Score = 29.6 bits (65), Expect = 3.3, Method: Compositional matrix adjust. Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 3/97 (3%) Query: 295 PNLQVIGGNVVTAAQAKNLIDAG--VDALRVGMGSGS-ICITQEVLACGRPQATAVYKVS 351 P L V G VV NL DAG V+A R +G+ + ++ A +A + V+ Sbjct: 9 PCLDVHAGRVVKGVNFVNLRDAGDPVEAARAYDEAGADELVFLDISATHEERAILLDVVA 68 Query: 352 EYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGS 388 A R +P+ GG++++ K L GA V + S Sbjct: 69 RVAERVFIPLTVGGGVRSLEDARKLLLSGADKVSVNS 105 >4Q4K-A nrPDB Length = 357 Score = 32.3 bits (72), Expect = 0.54, Method: Compositional matrix adjust. Identities = 20/58 (34%), Positives = 29/58 (50%) Query: 350 VSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIR 407 V A R +PV+A GGI + I AL LGAS V MG+ E+ + + ++ Sbjct: 202 VRLLAARGSLPVVAAGGIMDGRGIRAALELGASAVQMGTAFVLCPESSANAAYREALK 259 Score = 28.5 bits (62), Expect = 7.4, Method: Compositional matrix adjust. Identities = 12/41 (29%), Positives = 25/41 (60%) Query: 51 LTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFI 91 +T T+ + ++ P++ +PM V+ +A A++ GG+G I Sbjct: 1 MTDRFTRLLGIQQPIIQAPMLGVSTPALAAAVSNAGGLGSI 41 >4S2R-P nrPDB Length = 639 Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust. Identities = 33/138 (23%), Positives = 57/138 (41%), Gaps = 30/138 (21%) Query: 367 IQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM------ 420 ++++ H + LAL +S M+ LL +T EY R+K G +A Sbjct: 33 LRSLFHSERVLALTSSKPMVAYLLPSTDAHHSEYLADYDFRVKFLSGFSGSNAYVVVTDR 92 Query: 421 DKHLSSQNRYFSEA-----------------DKIKVAQGVSGAVQDKGSIHKFVPYLIAG 463 + L + RYF++A D I V + ++ +GS+ F P L Sbjct: 93 EALLWTDGRYFTQAGNQLDSNSWKLMKQGQPDSITVVDWLVRELE-RGSVIGFDPTL--- 148 Query: 464 IQHSCQDIGAKSLTQVRA 481 S D G+K+ +++A Sbjct: 149 ---STFDAGSKTFKRLKA 163 >5ZKN-A nrPDB Length = 241 Score = 30.8 bits (68), Expect = 1.5, Method: Compositional matrix adjust. Identities = 34/132 (25%), Positives = 57/132 (43%), Gaps = 21/132 (15%) Query: 263 LAQAGVDVVVLDSSQGNSIFQI---NMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVD 319 L GV ++ +D+++ + N I IK+KYPN Q+ ++ + +D + Sbjct: 106 LINEGVQIIAIDATKRERPDRKDLKNFIAEIKEKYPN-QLFMADISS-------VDEALY 157 Query: 320 ALRVGMGSGSICITQEVLACGRPQATAVYKVSE----YARRFGVPVIADGGIQNVGHIAK 375 A ++G + G T YK E + +PVIA+G I K Sbjct: 158 AEKIGFDIVGTTL------VGYTDYTKNYKALEELKKVVKVVKIPVIAEGNIDTPLKAKK 211 Query: 376 ALALGASTVMMG 387 AL +GA V++G Sbjct: 212 ALEIGAFAVVVG 223 >3EOD-A nrPDB Length = 130 Score = 30.8 bits (68), Expect = 1.5, Method: Compositional matrix adjust. Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 17/91 (18%) Query: 300 IGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLAC--GRPQATAVYKVSEYARRF 357 +G V AA GVDAL + G T +++ C P+ + K+ E+ R Sbjct: 30 LGATTVLAAD-------GVDALELLGG-----FTPDLMICDIAMPRMNGL-KLLEHIRNR 76 Query: 358 G--VPVIADGGIQNVGHIAKALALGASTVMM 386 G PV+ +N+ IAKAL LG V++ Sbjct: 77 GDQTPVLVISATENMADIAKALRLGVEDVLL 107 >6QVC-B nrPDB Length = 988 Score = 30.4 bits (67), Expect = 2.1, Method: Compositional matrix adjust. Identities = 17/69 (24%), Positives = 37/69 (53%), Gaps = 4/69 (5%) Query: 162 DIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAI 221 D+ + + ++ F+E+IM + D+ A T E +LQ + LP+V+ D ++ + Sbjct: 592 DLGWNQLSKYTIFVEDIMVR--DVKFVSASYTYGELRTLLQTTTVKTLPLVDSKDSMILL 649 Query: 222 --IARTDLK 228 + R++L+ Sbjct: 650 GSVERSELQ 658 >4B5T-A nrPDB Length = 251 Score = 30.0 bits (66), Expect = 2.4, Method: Compositional matrix adjust. Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 9/106 (8%) Query: 258 YRLDLLAQAGVDVVVLDSSQGNSIFQ--INMIKYIKDKYPNLQVIGGNVVTAAQAKNLID 315 Y +LLA AG D +++D + Q + ++ I YP+ V+ + Q K L+D Sbjct: 26 YSAELLAGAGFDWLLIDGEHAPNNVQTVLTQLQAIA-PYPSQPVVRPSWNDPVQIKQLLD 84 Query: 316 AGVDALRVGMGSGSICITQEVLACGRPQA------TAVYKVSEYAR 355 G L V M + + V A P A +A+ + S + R Sbjct: 85 VGTQTLLVPMVQNADEAREAVRATRYPPAGIRGVGSALARASRWNR 130 >2V5J-A nrPDB Length = 287 Score = 30.0 bits (66), Expect = 2.5, Method: Compositional matrix adjust. Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 9/106 (8%) Query: 258 YRLDLLAQAGVDVVVLDSSQGNSIFQ--INMIKYIKDKYPNLQVIGGNVVTAAQAKNLID 315 Y +LLA AG D +++D + Q + ++ I YP+ V+ + Q K L+D Sbjct: 51 YSAELLAGAGFDWLLIDGEHAPNNVQTVLTQLQAIA-PYPSQPVVRPSWNDPVQIKQLLD 109 Query: 316 AGVDALRVGMGSGSICITQEVLACGRPQA------TAVYKVSEYAR 355 G L V M + + V A P A +A+ + S + R Sbjct: 110 VGTQTLLVPMVQNADEAREAVRATRYPPAGIRGVGSALARASRWNR 155 >6OD1-A nrPDB Length = 337 Score = 30.0 bits (66), Expect = 2.6, Method: Compositional matrix adjust. Identities = 24/74 (32%), Positives = 37/74 (50%), Gaps = 10/74 (13%) Query: 317 GVDALRVGMGSGSICITQEVLAC--GRPQATAVYKVSEYARRFG--VPVIADGGIQNVGH 372 GVDAL + G T +++ C P+ + K+ E+ R G PV+ +N+ Sbjct: 40 GVDALELLGG-----FTPDLMICPIAMPRMNGL-KLLEHIRNRGDQTPVLVISATENMAD 93 Query: 373 IAKALALGASTVMM 386 IAKAL LG V++ Sbjct: 94 IAKALRLGVEDVLL 107 >6DVI-A nrPDB Length = 394 Score = 29.6 bits (65), Expect = 3.2, Method: Compositional matrix adjust. Identities = 14/29 (48%), Positives = 19/29 (65%) Query: 359 VPVIADGGIQNVGHIAKALALGASTVMMG 387 PV+ D GI+ + KALA+GAS V +G Sbjct: 316 TPVLFDSGIRTGADVVKALAMGASAVGIG 344 >2RDU-A nrPDB Length = 387 Score = 29.6 bits (65), Expect = 3.4, Method: Compositional matrix adjust. Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 8/78 (10%) Query: 359 VPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKK--YR---- 412 V V DGG++ + KALALGA V +G + GE D + + K +R Sbjct: 303 VEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMA 362 Query: 413 --GMGSLDAMDKHLSSQN 428 G ++ +DK L +N Sbjct: 363 LSGCQNVKVIDKTLVRKN 380 >4UTT-A nrPDB Length = 229 Score = 29.6 bits (65), Expect = 3.7, Method: Compositional matrix adjust. Identities = 25/105 (23%), Positives = 48/105 (45%), Gaps = 9/105 (8%) Query: 291 KDKYPNLQVIGGNVVTAAQAK--------NLIDAGVDALRVGMGSGSICITQEVLACGRP 342 K K PN + + ++V A AK + ++ G++A ++G S ++ + Sbjct: 109 KRKRPNGENVK-DLVDAIHAKGRLAMADISTLEEGIEAEKLGFDCVSTTLSGYTPYSKQS 167 Query: 343 QATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMG 387 + + E + +PVI +G I + KAL LGA + ++G Sbjct: 168 NSVDFELLEELVKTVKIPVICEGRINTPEELKKALDLGAYSAVVG 212 >2Z6J-A nrPDB Length = 332 Score = 29.6 bits (65), Expect = 3.7, Method: Compositional matrix adjust. Identities = 37/138 (26%), Positives = 57/138 (41%), Gaps = 19/138 (13%) Query: 260 LDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVD 319 +DL+ + GV VV + N KY++ + ++ V + A AK + G D Sbjct: 81 VDLVIEEGVKVVTTGAG--------NPSKYMERFHEAGIIVIPVVPSVALAKRMEKIGAD 132 Query: 320 A-LRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALA 378 A + GM +G + R ATA+ +PVIA GGI + A Sbjct: 133 AVIAEGMEAGGHIGKLTTMTLVRQVATAI----------SIPVIAAGGIADGEGAAAGFM 182 Query: 379 LGASTVMMGSLLAATTEA 396 LGA V +G+ E+ Sbjct: 183 LGAEAVQVGTRFVVAKES 200 >5LSM-A nrPDB Length = 359 Score = 29.3 bits (64), Expect = 3.8, Method: Compositional matrix adjust. Identities = 13/30 (43%), Positives = 20/30 (66%) Query: 359 VPVIADGGIQNVGHIAKALALGASTVMMGS 388 +PVIA GGI + + A+ +GAS V +G+ Sbjct: 210 IPVIAAGGIVDATTVRAAMTMGASAVQVGT 239 Score = 28.9 bits (63), Expect = 6.3, Method: Compositional matrix adjust. Identities = 12/35 (34%), Positives = 23/35 (65%) Query: 55 LTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIG 89 LT+ ++ P++ +PM V + +AIA++ GG+G Sbjct: 5 LTRLFGIEFPIIQAPMAGVQGSALAIAVSEAGGLG 39 >4MDT-A nrPDB Length = 305 Score = 28.9 bits (63), Expect = 5.0, Method: Compositional matrix adjust. Identities = 25/105 (23%), Positives = 44/105 (41%), Gaps = 23/105 (21%) Query: 221 IIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQA----GVDVVVLDSS 276 I RTDL D+P +K + +LC + H+ ++ L A G+D +V++ + Sbjct: 38 IYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVN 97 Query: 277 QGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDAL 321 P + ++ G+ A L+DAG+D L Sbjct: 98 A-----------------PEIPIMDGS--AAPFVYLLLDAGIDEL 123 >5GVH-A nrPDB Length = 314 Score = 28.9 bits (63), Expect = 5.2, Method: Compositional matrix adjust. Identities = 36/113 (31%), Positives = 54/113 (47%), Gaps = 11/113 (9%) Query: 285 NMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRV-GMGSGSICITQEVLACGRPQ 343 N KYI++ N + V + + A+ + AG DA+ GM SG + Sbjct: 100 NPTKYIRELKENGTKVIPVVASDSLARMVERAGADAVIAEGMESGGHI----------GE 149 Query: 344 ATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEA 396 T V++ +R +PVIA GGI + +A A ALGA V MG+ A+ E+ Sbjct: 150 VTTFVLVNKVSRSVNIPVIAAGGIADGRGMAAAFALGAEAVQMGTRFVASVES 202 >3SGZ-A nrPDB Length = 352 Score = 28.9 bits (63), Expect = 6.1, Method: Compositional matrix adjust. Identities = 16/49 (32%), Positives = 25/49 (51%), Gaps = 4/49 (8%) Query: 359 VPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIR 407 + V DGG++ + KALALGA + +G + GE DG++ Sbjct: 273 IEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGE----DGVK 317 >3NZK-A nrPDB Length = 311 Score = 28.5 bits (62), Expect = 7.5, Method: Compositional matrix adjust. Identities = 11/34 (32%), Positives = 17/34 (50%) Query: 221 IIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHE 254 I RTDL D+P +K + +LC + H+ Sbjct: 43 IYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHD 76 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6I0M-A nrPDB 708 0.0 1JCN-A nrPDB 701 0.0 4Z87-A nrPDB 649 0.0 4AF0-B nrPDB 629 e-180 3TSB-A nrPDB 618 e-177 1VRD-A nrPDB 605 e-173 4FXS-A nrPDB 593 e-170 1ZFJ-A nrPDB 590 e-169 4DQW-A nrPDB 554 e-158 2CU0-A nrPDB 532 e-151 1AK5-A nrPDB 481 e-136 4XTI-A nrPDB 401 e-112 4MJM-A nrPDB 386 e-107 4FEZ-A nrPDB 369 e-102 5UQG-A nrPDB 368 e-102 1EEP-A nrPDB 352 2e-97 3FFS-A nrPDB 343 1e-94 5AHL-A nrPDB 342 3e-94 4QJ1-A nrPDB 329 2e-90 2BWG-A nrPDB 304 7e-83 5UPU-A nrPDB 304 8e-83 2C6Q-A nrPDB 299 2e-81 3R2G-A nrPDB 288 4e-78 1YPF-A nrPDB 245 3e-65 6BFG-A nrPDB 123 2e-28 2A85-A nrPDB 122 3e-28 4N6F-A nrPDB 71 1e-12 Sequences not found previously or not previously below threshold: 6DVI-A nrPDB 68 1e-11 5ZBN-A nrPDB 66 3e-11 1AL8-A nrPDB 63 4e-10 2CDH-0 nrPDB 61 1e-09 2RDU-A nrPDB 56 4e-08 3SGZ-A nrPDB 54 2e-07 2J6X-A nrPDB 50 2e-06 2YVX-A nrPDB 50 3e-06 1TYG-A nrPDB 49 5e-06 1WV2-A nrPDB 49 6e-06 2YVZ-A nrPDB 49 7e-06 5ZKN-A nrPDB 48 1e-05 3BW4-A nrPDB 47 2e-05 1SZG-A nrPDB 47 3e-05 1QCW-A nrPDB 46 3e-05 4Q4K-A nrPDB 46 4e-05 2GJN-A nrPDB 45 8e-05 1P0K-A nrPDB 44 2e-04 6B2E-C nrPDB 44 2e-04 5Z9Y-A nrPDB 42 4e-04 2Z6J-A nrPDB 41 0.001 1VHN-A nrPDB 40 0.002 3TE5-C nrPDB 40 0.004 4JEJ-A nrPDB 39 0.005 1EP3-A nrPDB 39 0.008 5UE9-A nrPDB 38 0.009 5LSM-A nrPDB 38 0.010 4HG0-A nrPDB 38 0.010 1RPX-A nrPDB 38 0.012 3PC3-A nrPDB 37 0.018 5GVH-A nrPDB 37 0.019 2HTM-A nrPDB 37 0.022 1MXS-A nrPDB 37 0.023 1KA9-F nrPDB 36 0.034 2UV7-A nrPDB 35 0.052 2GGG-A nrPDB 35 0.059 1VHC-A nrPDB 35 0.066 4EVZ-A nrPDB 35 0.068 2ZRW-A nrPDB 35 0.092 3IGS-A nrPDB 35 0.098 4MM1-A nrPDB 35 0.10 3SR7-A nrPDB 35 0.11 2L6D-A nrPDB 34 0.18 1XI3-A nrPDB 34 0.20 4XBS-A nrPDB 34 0.22 4X2R-A nrPDB 34 0.24 4WD0-A nrPDB 34 0.24 2ZBT-A nrPDB 33 0.34 3O07-A nrPDB 33 0.38 4COO-A nrPDB 33 0.39 5CSS-A nrPDB 33 0.40 1N7K-A nrPDB 33 0.40 4IQL-A nrPDB 33 0.43 6DU6-A nrPDB 32 0.46 6CTY-A nrPDB 32 0.47 1QAP-A nrPDB 32 0.49 5DO8-B nrPDB 32 0.71 4UTT-A nrPDB 32 0.72 6NKE-A nrPDB 32 0.74 1IBJ-A nrPDB 32 0.95 2A1T-A nrPDB 31 1.0 3OIX-A nrPDB 31 1.2 4AXK-A nrPDB 31 1.2 2ISS-A nrPDB 31 1.3 2B7N-A nrPDB 31 1.4 3M6M-D nrPDB 31 1.5 3ZUY-A nrPDB 31 1.6 4HDR-A nrPDB 30 1.7 4KCV-B nrPDB 30 1.7 4MWA-D nrPDB 30 1.8 4KRZ-A nrPDB 30 1.8 4ADT-A nrPDB 30 2.0 1TQJ-A nrPDB 30 2.0 2CTZ-A nrPDB 30 2.1 4IP7-A nrPDB 30 2.1 5LNS-A nrPDB 30 2.1 2NV2-A nrPDB 30 2.5 1MZH-A nrPDB 30 2.5 5LNT-A nrPDB 30 2.6 3Q58-A nrPDB 30 2.7 1EYE-A nrPDB 30 2.7 2P8U-A nrPDB 30 3.0 6HYE-A nrPDB 30 3.0 5VIS-A nrPDB 30 3.1 4NU7-A nrPDB 30 3.5 3NWR-A nrPDB 30 3.5 2VEP-A nrPDB 30 3.5 1VR9-A nrPDB 29 4.2 1TJR-A nrPDB 29 4.4 5G1T-A nrPDB 29 4.5 4WY0-A nrPDB 29 4.7 2W6R-A nrPDB 29 5.0 3OA3-A nrPDB 29 5.3 3OVQ-A nrPDB 29 5.4 6OMZ-A nrPDB 29 5.5 3MDE-A nrPDB 29 6.2 3DM5-A nrPDB 29 7.0 1A3W-A nrPDB 29 7.4 4FIQ-A nrPDB 28 8.5 2YZR-A nrPDB 28 8.7 4J9J-A nrPDB 28 9.2 2B2H-A nrPDB 28 9.2 >6I0M-A nrPDB Length = 517 Score = 708 bits (1828), Expect = 0.0, Method: Composition-based stats. Identities = 514/514 (100%), Positives = 514/514 (100%) Query: 1 MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKIT 60 MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKIT Sbjct: 4 MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKIT 63 Query: 61 LKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVV 120 LKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVV Sbjct: 64 LKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVV 123 Query: 121 LSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMT 180 LSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMT Sbjct: 124 LSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMT 183 Query: 181 KREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDA 240 KREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDA Sbjct: 184 KREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDA 243 Query: 241 KKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVI 300 KKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVI Sbjct: 244 KKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVI 303 Query: 301 GGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVP 360 GGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVP Sbjct: 304 GGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVP 363 Query: 361 VIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM 420 VIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM Sbjct: 364 VIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM 423 Query: 421 DKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVR 480 DKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVR Sbjct: 424 DKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVR 483 Query: 481 AMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF 514 AMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF Sbjct: 484 AMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF 517 >1JCN-A nrPDB Length = 514 Score = 701 bits (1810), Expect = 0.0, Method: Composition-based stats. Identities = 430/514 (83%), Positives = 470/514 (91%) Query: 1 MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKIT 60 MADYLISGGT YVP+DGLTAQQLF D LTYNDFLILPG+IDF AD+VDLTSALT+KIT Sbjct: 1 MADYLISGGTGYVPEDGLTAQQLFASADDLTYNDFLILPGFIDFIADEVDLTSALTRKIT 60 Query: 61 LKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVV 120 LKTPL+SSPMDTVTEA MAIAMAL GGIGFIHHNCTPEFQANEVRKVK +EQGFITDPVV Sbjct: 61 LKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKNFEQGFITDPVV 120 Query: 121 LSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMT 180 LSP V DV EAK RHGF GIPIT+TG MGS+LVGI++SRDIDFL E++H L E+MT Sbjct: 121 LSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMT 180 Query: 181 KREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDA 240 R +LVVAPAG+TLKEANEILQRSKKGKLPIVN+ DELVAIIARTDLKKNRDYPLASKD+ Sbjct: 181 PRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDS 240 Query: 241 KKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVI 300 +KQLLCGAA+GT EDDKYRLDLL QAGVDV+VLDSSQGNS++QI M+ YIK KYP+LQVI Sbjct: 241 QKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVI 300 Query: 301 GGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVP 360 GGNVVTAAQAKNLIDAGVD LRVGMG GSICITQEV+ACGRPQ TAVYKV+EYARRFGVP Sbjct: 301 GGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVP 360 Query: 361 VIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM 420 +IADGGIQ VGH+ KALALGASTVMMGSLLAATTEAPGEYFFSDG+RLKKYRGMGSLDAM Sbjct: 361 IIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAM 420 Query: 421 DKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVR 480 +K SSQ RYFSE DK+K+AQGVSG++QDKGSI KFVPYLIAGIQH CQDIGA+SL+ +R Sbjct: 421 EKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLR 480 Query: 481 AMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF 514 +MMYSGELKFEKRT SAQ+EGGVH LHSYEKRL+ Sbjct: 481 SMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY 514 >4Z87-A nrPDB Length = 525 Score = 649 bits (1674), Expect = 0.0, Method: Composition-based stats. Identities = 326/512 (63%), Positives = 396/512 (77%), Gaps = 11/512 (2%) Query: 10 TSYVPDDGLTAQQLFNCGD--GLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVS 67 +Y DGL+ +QL + GLTYNDFL+LPG IDF + +V L+S LTKKITL P VS Sbjct: 17 ATYAEKDGLSVEQLMDSKTRGGLTYNDFLVLPGKIDFPSSEVVLSSRLTKKITLNAPFVS 76 Query: 68 SPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRV 127 SPMDTVTEA MAI MAL GGIG IHHNCT E QA VR+VKKYE GFI PVV+ P V Sbjct: 77 SPMDTVTEADMAIHMALLGGIGIIHHNCTAEEQAEMVRRVKKYENGFINAPVVVGPDATV 136 Query: 128 RDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVV 187 DV K GF G P+TD G+ +L GII+SRDI F+++E + EIMTK D++ Sbjct: 137 ADVRRMKNEFGFAGFPVTDDGKPTGKLQGIITSRDIQFVEDET--LLVSEIMTK--DVIT 192 Query: 188 APAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDA-KKQLLC 246 GI L+EAN+IL+ +KKGKLPIV+E LV++++RTDL KN+ YPLASK A KQLLC Sbjct: 193 GKQGINLEEANQILKNTKKGKLPIVDEAGCLVSMLSRTDLMKNQSYPLASKSADTKQLLC 252 Query: 247 GAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVT 306 GAAIGT + D+ RL +L +AG+DVVVLDSSQGNS+FQINMIK+IK+ +P+LQVI GNVVT Sbjct: 253 GAAIGTIDADRQRLAMLVEAGLDVVVLDSSQGNSVFQINMIKWIKETFPDLQVIAGNVVT 312 Query: 307 AAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGG 366 QA +LI AG D LR+GMGSGSICITQEV+ACGRPQ TAVY V+++A +FGVP IADGG Sbjct: 313 REQAASLIHAGADGLRIGMGSGSICITQEVMACGRPQGTAVYNVTQFANQFGVPCIADGG 372 Query: 367 IQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKH--- 423 +QN+GHI KA+ALGASTVMMG +LA TTE+PGEYFF DG RLK YRGMGS+DAM K Sbjct: 373 VQNIGHITKAIALGASTVMMGGMLAGTTESPGEYFFRDGKRLKTYRGMGSIDAMQKTDVK 432 Query: 424 -LSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAM 482 ++ +RYFSE+DK+ VAQGV+G+V DKGSI K++PYL G+QHSCQDIG +SL + R Sbjct: 433 GNAATSRYFSESDKVLVAQGVTGSVIDKGSIKKYIPYLYNGLQHSCQDIGVRSLVEFREK 492 Query: 483 MYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF 514 + SG ++FE RT SAQ+EGGVH+LHSYEKRLF Sbjct: 493 VDSGSVRFEFRTPSAQLEGGVHNLHSYEKRLF 524 >4AF0-B nrPDB Length = 556 Score = 629 bits (1621), Expect = e-180, Method: Composition-based stats. Identities = 309/521 (59%), Positives = 384/521 (73%), Gaps = 23/521 (4%) Query: 12 YVPDDGLTAQQLFNC--GDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSP 69 Y DGL+ Q+L + GLTYNDFL+LPG+I+F A V L S TK I L TP +SSP Sbjct: 40 YPRGDGLSLQELMDSRKNGGLTYNDFLVLPGHINFPASDVSLQSKATKNIVLNTPFLSSP 99 Query: 70 MDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRD 129 MDTVTE MAIA+AL GG+G IHHNC+ E QA VR+VKKYE GFITDP+ L P V D Sbjct: 100 MDTVTEDRMAIALALHGGLGIIHHNCSAEEQAAMVRRVKKYENGFITDPLCLGPDATVGD 159 Query: 130 VFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAP 189 V E KA+ GFCG+PIT+TG S+L+GI++ RD+ F ++ + ++ +MT ++V Sbjct: 160 VLEIKAKFGFCGVPITETGEPDSKLLGIVTGRDVQF---QDAETPIKSVMTT--EVVTGS 214 Query: 190 AGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASK-DAKKQLLCGA 248 + ITL++AN +L+ +KKGKLPIV+ + LV+++AR+DL KN++YP ASK KQL CGA Sbjct: 215 SPITLEKANSLLRETKKGKLPIVDSNGHLVSLVARSDLLKNQNYPYASKVPESKQLYCGA 274 Query: 249 AIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAA 308 AIGT DK RL LLA+AG+DVVVLDSSQGNS++QI IK+IK YP + VI GNVVT Sbjct: 275 AIGTRPGDKDRLKLLAEAGLDVVVLDSSQGNSVYQIEFIKWIKQTYPKIDVIAGNVVTRE 334 Query: 309 QAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQ 368 QA LI AG D LR+GMGSGSICITQEV+A GRPQ TAVY V+E+A RFG+P IADGGI Sbjct: 335 QAAQLIAAGADGLRIGMGSGSICITQEVMAVGRPQGTAVYAVAEFASRFGIPCIADGGIG 394 Query: 369 NVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHL---- 424 N+GHIAKALALGAS VMMG LLA TTE+PGEYF+ +G R+K YRGMGS++AM+ Sbjct: 395 NIGHIAKALALGASAVMMGGLLAGTTESPGEYFYHEGKRVKVYRGMGSIEAMEHTQRGSA 454 Query: 425 -----------SSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGA 473 ++ RYFSEAD +KVAQGVSG V DKGSI+KFVPYL G+QHS QD G Sbjct: 455 SGKRSILGLDNAATARYFSEADAVKVAQGVSGDVADKGSINKFVPYLFTGLQHSLQDAGI 514 Query: 474 KSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF 514 KS++++ + SG L+FE RT+SAQ+EGGVH L+SY KRLF Sbjct: 515 KSVSELHSCARSGSLRFELRTASAQLEGGVHGLNSYTKRLF 555 >3TSB-A nrPDB Length = 511 Score = 618 bits (1593), Expect = e-177, Method: Composition-based stats. Identities = 196/481 (40%), Positives = 295/481 (61%), Gaps = 11/481 (2%) Query: 27 GDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTG 86 +GLT++D L++P D +V + + L++ + L PL+S+ MDTVTEA MAIAMA G Sbjct: 32 KEGLTFDDVLLVPAKSDVLPREVSVKTVLSESLQLNIPLISAGMDTVTEADMAIAMARQG 91 Query: 87 GIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITD 146 G+G IH N + E QA +V KVK+ E G I+DP L+P+ +V D ++ G+P+ + Sbjct: 92 GLGIIHKNMSIEQQAEQVDKVKRSESGVISDPFFLTPEHQVYDAEHLMGKYRISGVPVVN 151 Query: 147 TGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKK 206 +LVGII++RD+ F+ +++ + ++MTK E L+ AP G TL EA +ILQ+ K Sbjct: 152 N-LDERKLVGIITNRDMRFI--QDYSIKISDVMTK-EQLITAPVGTTLSEAEKILQKYKI 207 Query: 207 GKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQA 266 KLP+V+ + L +I D++K ++P ++KD + +LL GAA+G D R+D L +A Sbjct: 208 EKLPLVDNNGVLQGLITIKDIEKVIEFPNSAKDKQGRLLVGAAVGVTADAMTRIDALVKA 267 Query: 267 GVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMG 326 VD +VLD++ G+S I+ +K ++ KYP+L +I GNV TA K LI+AG + ++VG+G Sbjct: 268 SVDAIVLDTAHGHSQGVIDKVKEVRAKYPSLNIIAGNVATAEATKALIEAGANVVKVGIG 327 Query: 327 SGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMM 386 GSIC T+ V G PQ TAVY + AR+ G+PVIADGGI+ G + KALA GA VM+ Sbjct: 328 PGSICTTRVVAGVGVPQLTAVYDCATEARKHGIPVIADGGIKYSGDMVKALAAGAHVVML 387 Query: 387 GSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGA 446 GS+ A E+PGE G + K YRGMGS+ AM+K S++RYF E +K V +G+ G Sbjct: 388 GSMFAGVAESPGETEIYQGRQFKVYRGMGSVGAMEK--GSKDRYFQEGNKKLVPEGIEGR 445 Query: 447 VQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSL 506 V KG + V L+ G++ GA+ L +R +F + + + +E H + Sbjct: 446 VPYKGPLADTVHQLVGGLRAGMGYCGAQDLEFLRE-----NAQFIRMSGAGLLESHPHHV 500 Query: 507 H 507 Sbjct: 501 Q 501 >1VRD-A nrPDB Length = 494 Score = 605 bits (1561), Expect = e-173, Method: Composition-based stats. Identities = 198/480 (41%), Positives = 297/480 (61%), Gaps = 12/480 (2%) Query: 27 GDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTG 86 + LT++D L++P Y + V + + LT++I + PLVS+ MDTVTEA +A A+A G Sbjct: 14 KEALTFDDVLLVPQYSEVLPKDVKIDTRLTRQIRINIPLVSAAMDTVTEAALAKALAREG 73 Query: 87 GIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITD 146 GIG IH N TP+ QA +V VKK E G I DP+ ++P V++ + A + G+P+ D Sbjct: 74 GIGIIHKNLTPDEQARQVSIVKKTENGIIYDPITVTPDMTVKEAIDLMAEYKIGGLPVVD 133 Query: 147 TGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKK 206 RLVG++++RD+ F E+ ++++MT RE L+VAP I+L++A EIL + + Sbjct: 134 EE---GRLVGLLTNRDVRF--EKNLSKKIKDLMTPREKLIVAPPDISLEKAKEILHQHRI 188 Query: 207 GKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQA 266 KLP+V++D++LV +I D+ ++P A++D K +LL GAA+GT + R++ L +A Sbjct: 189 EKLPLVSKDNKLVGLITIKDIMSVIEHPNAARDEKGRLLVGAAVGTSPETMERVEKLVKA 248 Query: 267 GVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMG 326 GVDV+V+D++ G+S I ++ IK YP+L V+ GNV T + LI AG DA++VG+G Sbjct: 249 GVDVIVIDTAHGHSRRVIETLEMIKADYPDLPVVAGNVATPEGTEALIKAGADAVKVGVG 308 Query: 327 SGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMM 386 GSIC T+ V G PQ TAV + SE AR++ VP+IADGGI+ G I KALA GA +VM+ Sbjct: 309 PGSICTTRVVAGVGVPQLTAVMECSEVARKYDVPIIADGGIRYSGDIVKALAAGAESVMV 368 Query: 387 GSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGA 446 GS+ A T EAPGE G + K YRGMGSL AM S +RY E + V +G+ G Sbjct: 369 GSIFAGTEEAPGETILYQGRKYKAYRGMGSLGAMRS--GSADRYGQEGENKFVPEGIEGM 426 Query: 447 VQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSL 506 V KG++ V L+ G++ IGA+++ +++ + F K T + E H + Sbjct: 427 VPYKGTVKDVVHQLVGGLRSGMGYIGARTIKELQE-----KAVFVKITPAGVKESHPHDI 481 >4FXS-A nrPDB Length = 496 Score = 593 bits (1530), Expect = e-170, Method: Composition-based stats. Identities = 188/484 (38%), Positives = 279/484 (57%), Gaps = 14/484 (2%) Query: 26 CGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALT 85 + LT++D L++P + + DL + LTK I L P+VS+ MDTVTEA +AIA+A Sbjct: 7 AKEALTFDDVLLVPAHSTVLPNTADLRTRLTKNIALNIPMVSASMDTVTEARLAIALAQE 66 Query: 86 GGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPIT 145 GGIGFIH N + E QA +V +VK +E G +T PV + P+ + DV E HGF G P+ Sbjct: 67 GGIGFIHKNMSIEQQAAQVHQVKIFEAGVVTHPVTVRPEQTIADVMELTHYHGFAGFPVV 126 Query: 146 DTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSK 205 + LVGII+ RD+ F+ + + +MT +E L G T E E + +++ Sbjct: 127 TE---NNELVGIITGRDVRFVTDLTKS--VAAVMTPKERLATVKEGATGAEVQEKMHKAR 181 Query: 206 KGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQ 265 K+ +VN++ +L +I D K P A KD + +L GAA+G ++ R+ L + Sbjct: 182 VEKILVVNDEFQLKGMITAKDFHKAESKPNACKDEQGRLRVGAAVGAAPGNEERVKALVE 241 Query: 266 AGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGM 325 AGVDV+++DSS G+S + I+ + YP+L++IGGNV TA A+ LI+AGV A++VG+ Sbjct: 242 AGVDVLLIDSSHGHSEGVLQRIRETRAAYPHLEIIGGNVATAEGARALIEAGVSAVKVGI 301 Query: 326 GSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVM 385 G GSIC T+ V G PQ TA+ + A +G+PVIADGGI+ G I+KA+A GAS VM Sbjct: 302 GPGSICTTRIVTGVGVPQITAIADAAGVANEYGIPVIADGGIRFSGDISKAIAAGASCVM 361 Query: 386 MGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFS--EADKIKVAQGV 443 +GS+ A T EAPGE G K YRGMGSL AM K S +RYF A V +G+ Sbjct: 362 VGSMFAGTEEAPGEVILYQGRSYKAYRGMGSLGAMSK--GSSDRYFQTDNAADKLVPEGI 419 Query: 444 SGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGV 503 G + KG + + + + G++ G+ ++ +R + +F + + + E V Sbjct: 420 EGRIAYKGHLKEIIHQQMGGLRSCMGLTGSATVEDLRT-----KAQFVRISGAGMKESHV 474 Query: 504 HSLH 507 H + Sbjct: 475 HDVQ 478 >1ZFJ-A nrPDB Length = 491 Score = 590 bits (1522), Expect = e-169, Method: Composition-based stats. Identities = 184/484 (38%), Positives = 274/484 (56%), Gaps = 14/484 (2%) Query: 27 GDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTG 86 G T++D L++P ++VDL + L +TL P++++ MDTVT + MAIA+A G Sbjct: 9 KKGYTFDDVLLIPAESHVLPNEVDLKTKLADNLTLNIPIITAAMDTVTGSKMAIAIARAG 68 Query: 87 GIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITD 146 G+G IH N + QA EVRKVK+ E G I DP L+P+ +V + E R+ G+PI + Sbjct: 69 GLGVIHKNMSITEQAEEVRKVKRSENGVIIDPFFLTPEHKVSEAEELMQRYRISGVPIVE 128 Query: 147 TGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKK 206 T +LVGII++RD+ F+ + ++ + E MT E LV A G L+ A IL + Sbjct: 129 T-LANRKLVGIITNRDMRFISD--YNAPISEHMTS-EHLVTAAVGTDLETAERILHEHRI 184 Query: 207 GKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQA 266 KLP+V+ L +I D++K ++P A+KD +LL AA+G D R + L +A Sbjct: 185 EKLPLVDNSGRLSGLITIKDIEKVIEFPHAAKDEFGRLLVAAAVGVTSDTFERAEALFEA 244 Query: 267 GVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMG 326 G D +V+D++ G+S + I I+ +PN +I GN+ TA A+ L DAGVD ++VG+G Sbjct: 245 GADAIVIDTAHGHSAGVLRKIAEIRAHFPNRTLIAGNIATAEGARALYDAGVDVVKVGIG 304 Query: 327 SGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMM 386 GSIC T+ V G PQ TA+Y + AR +G +IADGGI+ G I KALA G + VM+ Sbjct: 305 PGSICTTRVVAGVGVPQVTAIYDAAAVAREYGKTIIADGGIKYSGDIVKALAAGGNAVML 364 Query: 387 GSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEA---DKIKVAQGV 443 GS+ A T EAPGE G + K YRGMGS+ AM K S +RYF + V +G+ Sbjct: 365 GSMFAGTDEAPGETEIYQGRKYKTYRGMGSIAAMKK--GSSDRYFQGSVNEANKLVPEGI 422 Query: 444 SGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGV 503 G V KG+ V ++ GI+ +GA + ++ +F + + + +E Sbjct: 423 EGRVAYKGAASDIVFQMLGGIRSGMGYVGAGDIQELHE-----NAQFVEMSGAGLIESHP 477 Query: 504 HSLH 507 H + Sbjct: 478 HDVQ 481 >4DQW-A nrPDB Length = 509 Score = 554 bits (1427), Expect = e-158, Method: Composition-based stats. Identities = 197/485 (40%), Positives = 286/485 (58%), Gaps = 14/485 (2%) Query: 26 CGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALT 85 + LT++D L++PGY + V L + LT+ I L PLVS+ MDTVTEA +AIAMA Sbjct: 25 SQEALTFDDVLLIPGYSEVLPKDVSLKTRLTRGIELNIPLVSAAMDTVTEARLAIAMAQE 84 Query: 86 GGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPIT 145 GGIG IH N E QA EVRKVKK+E + DPV ++P ++ ++ + +GF G P+ Sbjct: 85 GGIGIIHKNMGIEQQAAEVRKVKKHETAIVRDPVTVTPSTKIIELLQMAREYGFSGFPVV 144 Query: 146 DTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSK 205 + G LVGI++ RD+ +K D + IMT ++ LV A G L+E L ++ Sbjct: 145 EQGE----LVGIVTGRDLR-VKPNAGDT-VAAIMTPKDKLVTAREGTPLEEMKAKLYENR 198 Query: 206 KGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQ 265 K+ +V+E+ L ++ D++K + YPLASKD + +L GAA+GT D R+ L Sbjct: 199 IEKMLVVDENFYLRGLVTFRDIEKAKTYPLASKDEQGRLRVGAAVGTGADTGERVAALVA 258 Query: 266 AGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGM 325 AGVDVVV+D++ G+S I ++++K +P++QVIGGN+ TA AK L +AG DA++VG+ Sbjct: 259 AGVDVVVVDTAHGHSKGVIERVRWVKQTFPDVQVIGGNIATAEAAKALAEAGADAVKVGI 318 Query: 326 GSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVM 385 G GSIC T+ V G PQ +A+ V+ GVP+IADGGI+ G +AKA+ GA VM Sbjct: 319 GPGSICTTRIVAGVGVPQISAIANVAAALEGTGVPLIADGGIRFSGDLAKAMVAGAYCVM 378 Query: 386 MGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSE---ADKIKVAQG 442 MGS+ A T EAPGE G K YRGMGSL AM S +RYF + + V +G Sbjct: 379 MGSMFAGTEEAPGEIELFQGRSYKSYRGMGSLGAMSGSQGSSDRYFQDASAGAEKLVPEG 438 Query: 443 VSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGG 502 + G V KG++ V L+ G++ + G+ + Q+R + +F + T + E Sbjct: 439 IEGRVPYKGALSAIVHQLMGGLRAAMGYTGSADIQQMRT-----QPQFVRITGAGMAESH 493 Query: 503 VHSLH 507 VH + Sbjct: 494 VHDVQ 498 >2CU0-A nrPDB Length = 486 Score = 532 bits (1370), Expect = e-151, Method: Composition-based stats. Identities = 164/493 (33%), Positives = 274/493 (55%), Gaps = 25/493 (5%) Query: 17 GLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEA 76 G ++L G T++D L++P + VD+++ +T + L P++S+ MDTVTE Sbjct: 2 GKFVEKLEKAIKGYTFDDVLLIPQATEVEPKDVDVSTRITPNVKLNIPILSAAMDTVTEW 61 Query: 77 GMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKAR 136 MA+AMA GG+G IH N E Q +V++VK+ E+ + D + ++P + V + Sbjct: 62 EMAVAMAREGGLGVIHRNMGIEEQVEQVKRVKRAERLIVEDVITIAPDETVDFALFLMEK 121 Query: 137 HGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKE 196 HG G+P+ + ++VGII+ +DI ++E+MTK +++ P I ++E Sbjct: 122 HGIDGLPVVED----EKVVGIITKKDI----AAREGKLVKELMTK--EVITVPESIEVEE 171 Query: 197 ANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDD 256 A +I+ ++ +LP+V+E +LV +I +DL + Y A +D +LL AA+ D Sbjct: 172 ALKIMIENRIDRLPVVDERGKLVGLITMSDLVARKKYKNAVRDENGELLVAAAV--SPFD 229 Query: 257 KYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDA 316 R L +AGVDV+V+D++ +++ I +K ++ K + I GN+ +L Sbjct: 230 IKRAIELDKAGVDVIVVDTAHAHNLKAIKSMKEMRQKV-DADFIVGNIANPKAVDDLTF- 287 Query: 317 GVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKA 376 DA++VG+G GSIC T+ V G PQ TAV V++ A+ +G+ VIADGGI+ G I KA Sbjct: 288 -ADAVKVGIGPGSICTTRIVAGVGVPQITAVAMVADRAQEYGLYVIADGGIRYSGDIVKA 346 Query: 377 LALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEA-- 434 +A GA VM+G+LLA T EAPG+ +G + K+YRGMGSL AM K RY+ Sbjct: 347 IAAGADAVMLGNLLAGTKEAPGKEVIINGRKYKQYRGMGSLGAMMK--GGAERYYQGGYM 404 Query: 435 -DKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKR 493 + V +GV G V +G++ + + L+ G++ +GA+++ +++ + +F Sbjct: 405 KTRKFVPEGVEGVVPYRGTVSEVLYQLVGGLKAGMGYVGARNIRELKE-----KGEFVII 459 Query: 494 TSSAQVEGGVHSL 506 T + E H + Sbjct: 460 THAGIKESHPHDI 472 >1AK5-A nrPDB Length = 503 Score = 481 bits (1239), Expect = e-136, Method: Composition-based stats. Identities = 164/495 (33%), Positives = 254/495 (51%), Gaps = 33/495 (6%) Query: 31 TYNDFLILPGYI--DFTADQVDLTSALTK-------KITLKTPLVSSPMDTVTEAGMAIA 81 T+N++L++PG D V+L++ L K +I LK PLVS+ M +V+ MAIA Sbjct: 11 TFNEYLLIPGLSTVDCIPSNVNLSTPLVKFQKGQQSEINLKIPLVSAIMQSVSGEKMAIA 70 Query: 82 MALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCG 141 +A GGI FI + + E QA V VK ++ GF+ + P DV R Sbjct: 71 LAREGGISFIFGSQSIESQAAMVHAVKNFKAGFVVSDSNVKPDQTFADVLAISQRTTHNT 130 Query: 142 IPITDTGRMGSRLVGIISSRD--IDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANE 199 + +TD G L+G+++ RD ID + E + ++MT LV A L EAN+ Sbjct: 131 VAVTDDGTPHGVLLGLVTQRDYPIDLTQTETK---VSDMMTPFSKLVTAHQDTKLSEANK 187 Query: 200 ILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYR 259 I+ K LPI+++D L I+ R D +++ D++K+ L GA I T D + R Sbjct: 188 IIWEKKLNALPIIDDDQHLRYIVFRKDYDRSQVCHNELVDSQKRYLVGAGINTR-DFRER 246 Query: 260 LDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPN-LQVIGGNVVTAAQAKNLIDAGV 318 + L +AG DV+ +DSS G S +Q I +I++KY + ++V GN+V + L DAG Sbjct: 247 VPALVEAGADVLCIDSSDGFSEWQKITIGWIREKYGDKVKVGAGNIVDGEGFRYLADAGA 306 Query: 319 DALRVGMGSGSICITQEVLACGRPQATAVYKV----SEYARRFG--VPVIADGGIQNVGH 372 D +++G+G GSICIT+E GR QATAV V ++Y G +PV +DGGI H Sbjct: 307 DFIKIGIGGGSICITREQKGIGRGQATAVIDVVAERNKYFEETGIYIPVCSDGGIVYDYH 366 Query: 373 IAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRY-F 431 + ALA+GA +M+G A E+P +G +K+Y G GS A + RY Sbjct: 367 MTLALAMGADFIMLGRYFARFEESPTRKVTINGSVMKEYWGEGSSRARN-----WQRYDL 421 Query: 432 SEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFE 491 K+ +GV V G + V + ++ + + GA ++ Q+++ + K Sbjct: 422 GGKQKLSFEEGVDSYVPYAGKLKDNVEASLNKVKSTMCNCGALTIPQLQS-----KAKIT 476 Query: 492 KRTSSAQVEGGVHSL 506 +S + VEGG H + Sbjct: 477 LVSSVSIVEGGAHDV 491 >4XTI-A nrPDB Length = 413 Score = 401 bits (1030), Expect = e-112, Method: Composition-based stats. Identities = 221/405 (54%), Positives = 283/405 (69%), Gaps = 25/405 (6%) Query: 130 VFEAKARHGFCGIPITDTGRMGSRLVGIISSRD-------IDFLKEEEHDCFLEEIMTKR 182 + G+ + M S+ G ++ D IDF E L +TK+ Sbjct: 13 LEHLATYAEKDGLSV--EQLMDSKTRGGLTYNDFLVLPGKIDFPSSE---VVLSSRLTKK 67 Query: 183 EDL---VVAPAGITLKEANEILQRSKKGKLPIVNED---DELVAIIARTDLKKN--RDYP 234 L V+ T+ EA+ + + G + I++ + +E ++ R +N +D P Sbjct: 68 ITLNAPFVSSPMDTVTEADMAIHMALLGGIGIIHHNCTAEEQAEMVRRVKKYENGSQDGP 127 Query: 235 LASKDA-KKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDK 293 LASK A KQLLCGAAIGT + D+ RL +L +AG+DVVVLDSSQGNS+FQINMIK+IK+ Sbjct: 128 LASKSADTKQLLCGAAIGTIDADRQRLAMLVEAGLDVVVLDSSQGNSVFQINMIKWIKET 187 Query: 294 YPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEY 353 +P+LQVI GNVVT QA +LI AG D LR+GMGSGSICITQEV+ACGRPQ TAVY V+++ Sbjct: 188 FPDLQVIAGNVVTREQAASLIHAGADGLRIGMGSGSICITQEVMACGRPQGTAVYNVTQF 247 Query: 354 ARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRG 413 A +FGVP IADGG+QN+GHI KA+ALGASTVMMG +LA TTE+PGEYFF DG RLK YRG Sbjct: 248 ANQFGVPCIADGGVQNIGHITKAIALGASTVMMGGMLAGTTESPGEYFFRDGKRLKTYRG 307 Query: 414 MGSLDAMDKH----LSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQ 469 MGS+DAM K ++ +RYFSE+DK+ VAQGV+G+V DKGSI K++PYL G+QHSCQ Sbjct: 308 MGSIDAMQKTDVKGNAATSRYFSESDKVLVAQGVTGSVIDKGSIKKYIPYLYNGLQHSCQ 367 Query: 470 DIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF 514 DIG +SL + R + SG ++FE RT SAQ+EGGVH+LHSYEKRLF Sbjct: 368 DIGVRSLVEFREKVDSGSVRFEFRTPSAQLEGGVHNLHSYEKRLF 412 Score = 161 bits (406), Expect = 1e-39, Method: Composition-based stats. Identities = 71/119 (59%), Positives = 81/119 (68%), Gaps = 2/119 (1%) Query: 10 TSYVPDDGLTAQQLFNCGD--GLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVS 67 +Y DGL+ +QL + GLTYNDFL+LPG IDF + +V L+S LTKKITL P VS Sbjct: 17 ATYAEKDGLSVEQLMDSKTRGGLTYNDFLVLPGKIDFPSSEVVLSSRLTKKITLNAPFVS 76 Query: 68 SPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDR 126 SPMDTVTEA MAI MAL GGIG IHHNCT E QA VR+VKKYE G P+ D Sbjct: 77 SPMDTVTEADMAIHMALLGGIGIIHHNCTAEEQAEMVRRVKKYENGSQDGPLASKSADT 135 >4MJM-A nrPDB Length = 385 Score = 386 bits (991), Expect = e-107, Method: Composition-based stats. Identities = 132/375 (35%), Positives = 206/375 (54%), Gaps = 21/375 (5%) Query: 145 TDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRS 204 G ++ + + D+ +E L E + L+ A T+ EA+ + + Sbjct: 10 VKEGLTFDDVLLVPAKSDV-LPREVSVKTVLSESLQLNIPLISAG-MDTVTEADMAIAMA 67 Query: 205 KKGKLPIVNED------DELVAIIAR------TDLKKNRDYPLASKDAKKQLLCGAAIGT 252 ++G L I++++ E V + R D++K ++P ++KD + +LL GAA+G Sbjct: 68 RQGGLGIIHKNMSIEQQAEQVDKVKRSESGGIKDIEKVIEFPNSAKDKQGRLLVGAAVGV 127 Query: 253 HEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKN 312 D R+D L +A VD +VLD++ G+S I+ +K ++ KYP+L +I GNV TA K Sbjct: 128 TADAMTRIDALVKASVDAIVLDTAHGHSQGVIDKVKEVRAKYPSLNIIAGNVATAEATKA 187 Query: 313 LIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGH 372 LI+AG + ++VG+G GSIC T+ V G PQ TAVY + AR+ G+PVIADGGI+ G Sbjct: 188 LIEAGANVVKVGIGPGSICTTRVVAGVGVPQLTAVYDCATEARKHGIPVIADGGIKYSGD 247 Query: 373 IAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFS 432 + KALA GA VM+GS+ A E+PGE G + K YRGMGS+ AM+K S++RYF Sbjct: 248 MVKALAAGAHVVMLGSMFAGVAESPGETEIYQGRQFKVYRGMGSVGAMEK--GSKDRYFQ 305 Query: 433 EADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEK 492 E +K V +G+ G V KG + V L+ G++ GA+ L +R +F + Sbjct: 306 EGNKKLVPEGIEGRVPYKGPLADTVHQLVGGLRAGMGYCGAQDLEFLRE-----NAQFIR 360 Query: 493 RTSSAQVEGGVHSLH 507 + + +E H + Sbjct: 361 MSGAGLLESHPHHVQ 375 Score = 140 bits (352), Expect = 2e-33, Method: Composition-based stats. Identities = 43/91 (47%), Positives = 60/91 (65%) Query: 27 GDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTG 86 +GLT++D L++P D +V + + L++ + L PL+S+ MDTVTEA MAIAMA G Sbjct: 11 KEGLTFDDVLLVPAKSDVLPREVSVKTVLSESLQLNIPLISAGMDTVTEADMAIAMARQG 70 Query: 87 GIGFIHHNCTPEFQANEVRKVKKYEQGFITD 117 G+G IH N + E QA +V KVK+ E G I D Sbjct: 71 GLGIIHKNMSIEQQAEQVDKVKRSESGGIKD 101 >4FEZ-A nrPDB Length = 388 Score = 369 bits (948), Expect = e-102, Method: Composition-based stats. Identities = 123/350 (35%), Positives = 191/350 (54%), Gaps = 24/350 (6%) Query: 175 LEEIMTKREDL---VVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIAR------- 224 L +TK L +V+ + T+ EA + +++G + ++++ + A+ Sbjct: 35 LRTRLTKNIALNIPMVSASMDTVTEARLAIALAQEGGIGFIHKNMSIEQQAAQVHQVKIF 94 Query: 225 -----TDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGN 279 D K P A KD + +L GAA+G ++ R+ L +AGVDV+++DSS G+ Sbjct: 95 ESGGAKDFHKAESKPNACKDEQGRLRVGAAVGAAPGNEERVKALVEAGVDVLLIDSSHGH 154 Query: 280 SIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLAC 339 S + I+ + YP+L++IGGNV TA A+ LI+AGV A++VG+G GSIC T+ V Sbjct: 155 SEGVLQRIRETRAAYPHLEIIGGNVATAEGARALIEAGVSAVKVGIGPGSICTTRIVTGV 214 Query: 340 GRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGE 399 G PQ TA+ + A +G+PVIADGGI+ G I+KA+A GAS VM+GS+ A T EAPGE Sbjct: 215 GVPQITAIADAAGVANEYGIPVIADGGIRFSGDISKAIAAGASCVMVGSMFAGTEEAPGE 274 Query: 400 YFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFS--EADKIKVAQGVSGAVQDKGSIHKFV 457 G K YRGMGSL AM K S +RYF A V +G+ G + KG + + + Sbjct: 275 VILYQGRSYKAYRGMGSLGAMSK--GSSDRYFQTDNAADKLVPEGIEGRIAYKGHLKEII 332 Query: 458 PYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLH 507 + G++ G+ ++ +R + +F + + + E VH + Sbjct: 333 HQQMGGLRSCMGLTGSATVEDLRT-----KAQFVRISGAGMKESHVHDVQ 377 Score = 137 bits (346), Expect = 8e-33, Method: Composition-based stats. Identities = 43/92 (46%), Positives = 59/92 (64%) Query: 26 CGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALT 85 + LT++D L++P + + DL + LTK I L P+VS+ MDTVTEA +AIA+A Sbjct: 10 AKEALTFDDVLLVPAHSTVLPNTADLRTRLTKNIALNIPMVSASMDTVTEARLAIALAQE 69 Query: 86 GGIGFIHHNCTPEFQANEVRKVKKYEQGFITD 117 GGIGFIH N + E QA +V +VK +E G D Sbjct: 70 GGIGFIHKNMSIEQQAAQVHQVKIFESGGAKD 101 >5UQG-A nrPDB Length = 406 Score = 368 bits (944), Expect = e-102, Method: Composition-based stats. Identities = 146/353 (41%), Positives = 208/353 (58%), Gaps = 26/353 (7%) Query: 171 HDCFLEEIMTKREDL---VVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIA---- 223 + + +TK L +++ A T+ E + ++ G L +++++ ++ + + Sbjct: 49 KEVKIHTKLTKNITLNMPLISAAMDTVTEHRAAIMMARLGGLGVIHKNMDIASQVREVKR 108 Query: 224 --------RTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDS 275 DLKK ++YP A+KD +L GAAIG + D R+D L +AGVDVVVLDS Sbjct: 109 VKKSESGGIKDLKKRKEYPDANKDNFGRLRVGAAIGVGQMD--RVDALVEAGVDVVVLDS 166 Query: 276 SQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQE 335 + G+S I+ +K IK KYPNL +I GN+ TAA AK L +AGVDA++VG+G GSIC T+ Sbjct: 167 AHGHSKGIIDTVKAIKAKYPNLDLIAGNIATAAAAKALCEAGVDAVKVGIGPGSICTTRI 226 Query: 336 VLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTE 395 V G PQ +A+ + E A +FGVPVIADGGI+ G IAKALA+GAS+VM+GSLLA T E Sbjct: 227 VSGVGVPQISAIDECVEEANKFGVPVIADGGIKYSGDIAKALAVGASSVMIGSLLAGTDE 286 Query: 396 APGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEA--DKIKVAQGVSGAVQDKGSI 453 +PGE F G + K YRGMGSL AM K S +RYF + V +G+ G V GSI Sbjct: 287 SPGELFTYQGRQYKSYRGMGSLGAMQK--GSSDRYFQQGTAQDKLVPEGIEGRVPYVGSI 344 Query: 454 HKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSL 506 V L+ G++ S +GAK + + +F + T++ E VH + Sbjct: 345 RSVVHQLLGGLRSSMGYVGAKDIEDFQ-----KRAEFVEITTAGLKESHVHDV 392 Score = 134 bits (338), Expect = 8e-32, Method: Composition-based stats. Identities = 43/91 (47%), Positives = 54/91 (59%) Query: 27 GDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTG 86 LT+ D L+ PGY + +V + + LTK ITL PL+S+ MDTVTE AI MA G Sbjct: 29 KRALTFEDVLLRPGYSEVLPKEVKIHTKLTKNITLNMPLISAAMDTVTEHRAAIMMARLG 88 Query: 87 GIGFIHHNCTPEFQANEVRKVKKYEQGFITD 117 G+G IH N Q EV++VKK E G I D Sbjct: 89 GLGVIHKNMDIASQVREVKRVKKSESGGIKD 119 >1EEP-A nrPDB Length = 404 Score = 352 bits (904), Expect = 2e-97, Method: Composition-based stats. Identities = 122/382 (31%), Positives = 190/382 (49%), Gaps = 52/382 (13%) Query: 172 DCFLEEIMTKREDL---VVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAI------- 221 + L+ +TK L ++ A T+ E+ + +K+G + I++++ + A Sbjct: 28 EVSLKTQLTKNISLNIPFLSSAMDTVTESQMAIAIAKEGGIGIIHKNMSIEAQRKEIEKV 87 Query: 222 ----------------------------IARTDLKKN----RDYPLASKDAKKQLLCGAA 249 + ++D KN D+P A KD +L GAA Sbjct: 88 KTYKFQKTINTNGDTNEQKPEIFTAKQHLEKSDAYKNAEHKEDFPNACKDLNNKLRVGAA 147 Query: 250 IGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQ 309 + D R++ L +A VD++V+DS+ G+S I +IK IK KYPNL +I GN+VT Sbjct: 148 VSIDIDTIERVEELVKAHVDILVIDSAHGHSTRIIELIKKIKTKYPNLDLIAGNIVTKEA 207 Query: 310 AKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQN 369 A +LI G D L+VG+G GSIC T+ V G PQ TA+ V E + +IADGGI+ Sbjct: 208 ALDLISVGADCLKVGIGPGSICTTRIVAGVGVPQITAICDVYEACNNTNICIIADGGIRF 267 Query: 370 VGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNR 429 G + KA+A GA +VM+G+L A T E+P E +G + K Y GMGS+ AM + S++R Sbjct: 268 SGDVVKAIAAGADSVMIGNLFAGTKESPSEEIIYNGKKFKSYVGMGSISAMKR--GSKSR 325 Query: 430 YFSEAD---KIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSG 486 YF + K V +G+ G V G + + L G+ +GA +++ ++ Sbjct: 326 YFQLENNEPKKLVPEGIEGMVPYSGKLKDILTQLKGGLMSGMGYLGAATISDLKI----- 380 Query: 487 ELKFEKRTSSAQVEGGVHSLHS 508 KF K + S+ E H + S Sbjct: 381 NSKFVKISHSSLKESHPHDVFS 402 Score = 131 bits (329), Expect = 7e-31, Method: Composition-based stats. Identities = 39/86 (45%), Positives = 53/86 (61%) Query: 26 CGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALT 85 + LT++D ++P +V L + LTK I+L P +SS MDTVTE+ MAIA+A Sbjct: 6 TKEALTFDDVSLIPRKSSVLPSEVSLKTQLTKNISLNIPFLSSAMDTVTESQMAIAIAKE 65 Query: 86 GGIGFIHHNCTPEFQANEVRKVKKYE 111 GGIG IH N + E Q E+ KVK Y+ Sbjct: 66 GGIGIIHKNMSIEAQRKEIEKVKTYK 91 >3FFS-A nrPDB Length = 400 Score = 343 bits (879), Expect = 1e-94, Method: Composition-based stats. Identities = 126/315 (40%), Positives = 172/315 (54%), Gaps = 12/315 (3%) Query: 194 LKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTH 253 LK N I K P N D E Y + D K +L GAAIG + Sbjct: 85 LKVKNWISNLEKNESTPDQNLDKESTDGKDTKSNNNIDAYSNENLDNKGRLRVGAAIGVN 144 Query: 254 EDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNL 313 + R LL +AGVDV+VLDS+ G+S+ I +K IK K N+ VI GNVVT K L Sbjct: 145 --EIERAKLLVEAGVDVIVLDSAHGHSLNIIRTLKEIKSKM-NIDVIVGNVVTEEATKEL 201 Query: 314 IDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHI 373 I+ G D ++VG+G GSIC T+ V G PQ TA+ K S A +FG+P+IADGGI+ G I Sbjct: 202 IENGADGIKVGIGPGSICTTRIVAGVGVPQITAIEKCSSVASKFGIPIIADGGIRYSGDI 261 Query: 374 AKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSE 433 KALA+GAS+VM+GS+LA T E+PGE K YRGMGS+ AM S +RYF E Sbjct: 262 GKALAVGASSVMIGSILAGTEESPGEKELIGDTVYKYYRGMGSVGAMKS--GSGDRYFQE 319 Query: 434 --ADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFE 491 + V +G+ G V+ KG + V L+ G++ +G+ S+ ++ + + Sbjct: 320 KRPENKMVPEGIEGRVKYKGEMEGVVYQLVGGLRSCMGYLGSASIEEL-----WKKSSYV 374 Query: 492 KRTSSAQVEGGVHSL 506 + T+S E VH + Sbjct: 375 EITTSGLRESHVHDV 389 Score = 129 bits (325), Expect = 2e-30, Method: Composition-based stats. Identities = 46/104 (44%), Positives = 59/104 (56%), Gaps = 2/104 (1%) Query: 25 NCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMAL 84 N G GLT+ D L++P Y + +V L + LTK ++LK PL+SS MDTVTE MA+ MA Sbjct: 5 NIGKGLTFEDILLVPNYSEVLPREVSLETKLTKNVSLKIPLISSAMDTVTEHLMAVGMAR 64 Query: 85 TGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVR 128 GGIG IH N E Q NEV KVK + + P + Sbjct: 65 LGGIGIIHKNMDMESQVNEVLKVKNWISNLEKNEST--PDQNLD 106 >5AHL-A nrPDB Length = 400 Score = 342 bits (876), Expect = 3e-94, Method: Composition-based stats. Identities = 130/349 (37%), Positives = 199/349 (57%), Gaps = 17/349 (4%) Query: 171 HDCFLEEIMTKREDL---VVAPAGITLKEANEILQRSKKGKLPIVNEDDEL------VAI 221 D L+ +T+ +L +V+ A T+ EA + +++G + I++++ + V Sbjct: 46 KDVSLKTRLTRGIELNIPLVSAAMDTVTEARLAIAMAQEGGIGIIHKNMGIEQQAAEVRK 105 Query: 222 IARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSI 281 + + + K + YPLASKD + +L GAA+GT D R+ L AGVDVVV+D++ G+S Sbjct: 106 VKKHETAKAKTYPLASKDEQGRLRVGAAVGTGADTGERVAALVAAGVDVVVVDTAHGHSK 165 Query: 282 FQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGR 341 I ++++K +P++QVIGGN+ TA AK L +AG DA++VG+G GSIC T+ V G Sbjct: 166 GVIERVRWVKQTFPDVQVIGGNIATAEAAKALAEAGADAVKVGIGPGSICTTRIVAGVGV 225 Query: 342 PQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYF 401 PQ +A+ V+ GVP+IADGGI+ G +AKA+ GA VMMGS+ A T EAPGE Sbjct: 226 PQISAIANVAAALEGTGVPLIADGGIRFSGDLAKAMVAGAYCVMMGSMFAGTEEAPGEIE 285 Query: 402 FSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSE---ADKIKVAQGVSGAVQDKGSIHKFVP 458 G K YRGMGSL AM S +RYF + + V +G+ G V KG++ V Sbjct: 286 LFQGRSYKSYRGMGSLGAMSGSQGSSDRYFQDASAGAEKLVPEGIEGRVPYKGALSAIVH 345 Query: 459 YLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLH 507 L+ G++ + G+ + Q+R + +F + T + E VH + Sbjct: 346 QLMGGLRAAMGYTGSADIQQMRT-----QPQFVRITGAGMAESHVHDVQ 389 Score = 137 bits (344), Expect = 1e-32, Method: Composition-based stats. Identities = 47/88 (53%), Positives = 58/88 (65%) Query: 26 CGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALT 85 + LT++D L++PGY + V L + LT+ I L PLVS+ MDTVTEA +AIAMA Sbjct: 25 SQEALTFDDVLLIPGYSEVLPKDVSLKTRLTRGIELNIPLVSAAMDTVTEARLAIAMAQE 84 Query: 86 GGIGFIHHNCTPEFQANEVRKVKKYEQG 113 GGIG IH N E QA EVRKVKK+E Sbjct: 85 GGIGIIHKNMGIEQQAAEVRKVKKHETA 112 >4QJ1-A nrPDB Length = 361 Score = 329 bits (843), Expect = 2e-90, Method: Composition-based stats. Identities = 126/341 (36%), Positives = 188/341 (55%), Gaps = 25/341 (7%) Query: 171 HDCFLEEIMTKREDL---VVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDL 227 + LE +TK L +++ A T+ E + ++ G + I++++ ++ + + Sbjct: 30 REVSLETKLTKNVSLKIPLISSAMDTVTEHLMAVGMARLGGIGIIHKNMDMESQVNEVLK 89 Query: 228 KKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMI 287 KN L GAAIG + + R LL +AGVDV+VLDS+ G+S+ I + Sbjct: 90 VKN----------SGGLRVGAAIGVN--EIERAKLLVEAGVDVIVLDSAHGHSLNIIRTL 137 Query: 288 KYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAV 347 K IK K N+ VI GNVVT K LI+ G D ++VG+G GSIC T+ V G PQ TA+ Sbjct: 138 KEIKSKM-NIDVIVGNVVTEEATKELIENGADGIKVGIGPGSICTTRIVAGVGVPQITAI 196 Query: 348 YKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIR 407 K S A +FG+P+IADGGI+ G I KALA+GAS+VM+GS+LA T E+PGE Sbjct: 197 EKCSSVASKFGIPIIADGGIRYSGDIGKALAVGASSVMIGSILAGTEESPGEKELIGDTV 256 Query: 408 LKKYRGMGSLDAMDKHLSSQNRYFSE--ADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQ 465 K YRGMGS+ AM S +RYF E + V +G+ G V+ KG + V L+ G++ Sbjct: 257 YKYYRGMGSVGAMKS--GSGDRYFQEKRPENKMVPEGIEGRVKYKGEMEGVVYQLVGGLR 314 Query: 466 HSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSL 506 +G+ S+ ++ + + + T+S E VH + Sbjct: 315 SCMGYLGSASIEEL-----WKKSSYVEITTSGLRESHVHDV 350 Score = 126 bits (316), Expect = 3e-29, Method: Composition-based stats. Identities = 45/86 (52%), Positives = 55/86 (63%) Query: 25 NCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMAL 84 N G GLT+ D L++P Y + +V L + LTK ++LK PL+SS MDTVTE MA+ MA Sbjct: 8 NIGKGLTFEDILLVPNYSEVLPREVSLETKLTKNVSLKIPLISSAMDTVTEHLMAVGMAR 67 Query: 85 TGGIGFIHHNCTPEFQANEVRKVKKY 110 GGIG IH N E Q NEV KVK Sbjct: 68 LGGIGIIHKNMDMESQVNEVLKVKNS 93 >2BWG-A nrPDB Length = 367 Score = 304 bits (778), Expect = 7e-83, Method: Composition-based stats. Identities = 77/285 (27%), Positives = 135/285 (47%), Gaps = 12/285 (4%) Query: 211 IVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDV 270 ++++ AI L + + + + + + G ++ +K L A V Sbjct: 88 VMSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKF 147 Query: 271 VVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSI 330 + LD + G S + +K ++ K+P ++ GNVVT + LI +G D ++VG+G GS+ Sbjct: 148 ICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSV 207 Query: 331 CITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLL 390 C T+ G PQ +AV + ++ A +I+DGG G +AKA GA VM+G + Sbjct: 208 CTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMF 267 Query: 391 AATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDK 450 + TE GE +G +LK + GM S AM+KH Y + ++G + V K Sbjct: 268 SGHTECAGEVIERNGRKLKLFYGMSSDTAMNKHAGGVAEY-------RASEGKTVEVPYK 320 Query: 451 GSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTS 495 G + + ++ G++ +C +GA L ++ S F + T Sbjct: 321 GDVENTILDILGGLRSTCTYVGAAKLKEL-----SRRATFIRVTQ 360 Score = 45.1 bits (105), Expect = 8e-05, Method: Composition-based stats. Identities = 19/75 (25%), Positives = 31/75 (41%), Gaps = 5/75 (6%) Query: 30 LTYNDFLILPGYIDFTAD-QVDLTSALT----KKITLKTPLVSSPMDTVTEAGMAIAMAL 84 L + D L+ P + +VDL T K+ P++ + MDTV MA M+ Sbjct: 32 LDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQ 91 Query: 85 TGGIGFIHHNCTPEF 99 IH + + + Sbjct: 92 HSMFTAIHKHYSLDD 106 >5UPU-A nrPDB Length = 407 Score = 304 bits (778), Expect = 8e-83, Method: Composition-based stats. Identities = 116/342 (33%), Positives = 187/342 (54%), Gaps = 27/342 (7%) Query: 176 EEIMTKREDL---VVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRD 232 +TK+ L +V+ A T+ E+ + ++ G + +++ + + + ++ K Sbjct: 70 SSQLTKKIRLKVPLVSSAMDTVTESRMAIAMARAGGMGVLHRNLPVAEQAGQVEMVKR-- 127 Query: 233 YPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKD 292 LL GAA+G D R +L AGVDV+V+D++ ++ ++M+ +K Sbjct: 128 --------SGGLLVGAAVGVGGDAWVRAMMLVDAGVDVLVVDTAHAHNRLVLDMVGKLKS 179 Query: 293 KYPN-LQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVS 351 + + ++V+GGNV T + A L+DAG DA++VG+G GSIC T+ V G PQ TA+ + Sbjct: 180 EVGDRVEVVGGNVATRSAAAALVDAGADAVKVGVGPGSICTTRVVAGVGAPQITAILEAV 239 Query: 352 EYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKY 411 R GVPVIADGG+Q G IAKALA GAST M+GSLLA T EAPGE F +G + K Y Sbjct: 240 AACRPAGVPVIADGGLQYSGDIAKALAAGASTAMLGSLLAGTAEAPGELIFVNGKQYKSY 299 Query: 412 RGMGSLDAMDKHLS----SQNRYFSE---ADKIKVAQGVSGAVQDKGSIHKFVPYLIAGI 464 RGMGSL AM S++RYF++ ++ V +G+ G V +G + + L G+ Sbjct: 300 RGMGSLGAMRGRGGATSYSKDRYFADDALSEDKLVPEGIEGRVPFRGPLSSVIHQLTGGL 359 Query: 465 QHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSL 506 + + G+ ++ ++ + +F + T + E H + Sbjct: 360 RAAMGYTGSPTIEVLQ------QAQFVRITPAGLKESHPHDV 395 Score = 137 bits (344), Expect = 1e-32, Method: Composition-based stats. Identities = 61/154 (39%), Positives = 78/154 (50%), Gaps = 11/154 (7%) Query: 10 TSYVPDDGLTAQQLFNCGD--------GLTYNDFLILPGYIDFTADQVDLTSALTKKITL 61 + YV GLT + GD GLT++D L+LP D D +S LTKKI L Sbjct: 20 SPYVRMGGLTTDPVPTGGDDPHKVAMLGLTFDDVLLLPAASDVVPATADTSSQLTKKIRL 79 Query: 62 KTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVL 121 K PLVSS MDTVTE+ MAIAMA GG+G +H N QA +V VK+ + V + Sbjct: 80 KVPLVSSAMDTVTESRMAIAMARAGGMGVLHRNLPVAEQAGQVEMVKRSGGLLVGAAVGV 139 Query: 122 SPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLV 155 VR + A G + + DT +RLV Sbjct: 140 GGDAWVRAMMLVDA--GVD-VLVVDTAHAHNRLV 170 >2C6Q-A nrPDB Length = 351 Score = 299 bits (766), Expect = 2e-81, Method: Composition-based stats. Identities = 77/278 (27%), Positives = 135/278 (48%), Gaps = 12/278 (4%) Query: 218 LVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQ 277 A+ L + +++ + D + L + G+ + ++ L A V + LD + Sbjct: 83 FTAVHKHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICLDVAN 142 Query: 278 GNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVL 337 G S + +K ++ ++P ++ GNVVT + LI +G D ++VG+G GS+C T++ Sbjct: 143 GYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKT 202 Query: 338 ACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAP 397 G PQ +AV + ++ A +I+DGG G +AKA GA VM+G +LA +E+ Sbjct: 203 GVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESG 262 Query: 398 GEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFV 457 GE DG + K + GM S AM K+ Y + ++G + V KG + + Sbjct: 263 GELIERDGKKYKLFYGMSSEMAMKKYAGGVAEY-------RASEGKTVEVPFKGDVEHTI 315 Query: 458 PYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTS 495 ++ GI+ +C +GA L ++ S F + T Sbjct: 316 RDILGGIRSTCTYVGAAKLKEL-----SRRTTFIRVTQ 348 Score = 39.3 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 32/76 (42%), Gaps = 5/76 (6%) Query: 29 GLTYNDFLILPGYIDFTAD-QVDLTSALT----KKITLKTPLVSSPMDTVTEAGMAIAMA 83 L + D L+ P + +VDLT + + K+ P++++ MDTV MA + Sbjct: 19 SLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLC 78 Query: 84 LTGGIGFIHHNCTPEF 99 +H + + Sbjct: 79 KFSLFTAVHKHYSLVQ 94 >3R2G-A nrPDB Length = 361 Score = 288 bits (737), Expect = 4e-78, Method: Composition-based stats. Identities = 88/330 (26%), Positives = 151/330 (45%), Gaps = 31/330 (9%) Query: 186 VVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLL 245 V++ T+ E+N KG + A+ +++N K K + Sbjct: 45 VISANMDTITESNMANFMHSKGAMG---------ALHRFMTIEENIQ---EFKKCKGPVF 92 Query: 246 CGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVV 305 +G E++ R + L AG D +D + ++ + +K ++ + ++ GNV Sbjct: 93 VS--VGCTENELQRAEALRDAGADFFCVDVAHAHAKYVGKTLKSLRQLLGSRCIMAGNVA 150 Query: 306 TAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADG 365 T A A L G D ++ G+G GS+C T+ G P T + S R ++ADG Sbjct: 151 TYAGADYLASCGADIIKAGIGGGSVCSTRIKTGFGVPMLTCIQDCSRADR----SIVADG 206 Query: 366 GIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFS-DGIRLKKYRGMGSLDAMDKHL 424 GI+ G I KALA GA VM+G +LA + PGE F DG ++K+YRGM S +A + L Sbjct: 207 GIKTSGDIVKALAFGADFVMIGGMLAGSAPTPGEVFQKDDGSKVKRYRGMASREAQEAFL 266 Query: 425 SSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMY 484 + + K A+GV+ V K + + +I G++ GA S+++++ Sbjct: 267 GQMHEW-------KTAEGVATEVPFKENPDGIIADIIGGLRSGLTYAGADSISELQR--- 316 Query: 485 SGELKFEKRTSSAQVEGGVHSLHSYEKRLF 514 +L + T + ++E H L + L+ Sbjct: 317 --KLNYVIVTQAGRIESLPHKLLEGAENLY 344 Score = 107 bits (267), Expect = 1e-23, Method: Composition-based stats. Identities = 28/83 (33%), Positives = 47/83 (56%), Gaps = 2/83 (2%) Query: 28 DGLTYNDFLILPGYIDFTADQVDLTSALTK--KITLKTPLVSSPMDTVTEAGMAIAMALT 85 +T++D L++P Y + +V T++ + K+TL P++S+ MDT+TE+ MA M Sbjct: 6 QAITFDDVLLVPSYNHHESRRVVETTSTDRLGKLTLNLPVISANMDTITESNMANFMHSK 65 Query: 86 GGIGFIHHNCTPEFQANEVRKVK 108 G +G +H T E E +K K Sbjct: 66 GAMGALHRFMTIEENIQEFKKCK 88 >1YPF-A nrPDB Length = 336 Score = 245 bits (626), Expect = 3e-65, Method: Composition-based stats. Identities = 81/252 (32%), Positives = 126/252 (50%), Gaps = 22/252 (8%) Query: 238 KDAKKQ-LLCGAAIGTHEDDKYRLDLLAQAGV--DVVVLDSSQGNSIFQINMIKYIKDKY 294 +D + + L+ ++G ED+ + LA + + + +D + G+S INMI++IK Sbjct: 88 RDMQSRGLIASISVGVKEDEYEFVQQLAAEHLTPEYITIDIAHGHSNAVINMIQHIKKHL 147 Query: 295 PNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVL--ACGRPQATAVYKVSE 352 P VI GNV T + L +AG DA +VG+G G +CIT+ G Q A+ ++ Sbjct: 148 PESFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAK 207 Query: 353 YARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYR 412 A + P+IADGGI+ G +AK++ GA+ VM+GSL A E+PGE DG K+Y Sbjct: 208 AASK---PIIADGGIRTNGDVAKSIRFGATMVMIGSLFAGHEESPGETIEKDGKLYKEYF 264 Query: 413 GMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIG 472 G S F + +K V +G V+ KGS+ + + +Q S G Sbjct: 265 GSAS-------------EFQKGEKKNV-EGKKMFVEHKGSLEDTLIEMEQDLQSSISYAG 310 Query: 473 AKSLTQVRAMMY 484 L +R + Y Sbjct: 311 GTKLDSIRTVDY 322 Score = 44.7 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 25/121 (20%), Positives = 47/121 (38%), Gaps = 3/121 (2%) Query: 17 GLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEA 76 G + + G+ Y D ++P + T+ K K P+V + M T+ + Sbjct: 1 GSSHHHHHHMGNVFDYEDIQLIPAKCIVNSRSECDTTVTLGKHKFKLPVVPANMQTIIDE 60 Query: 77 GMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKAR 136 +A +A +H PE + + +R ++ +G I V +D V + A Sbjct: 61 RIATYLAENNYFYIMHRFQ-PEKRISFIRDMQS--RGLIASISVGVKEDEYEFVQQLAAE 117 Query: 137 H 137 H Sbjct: 118 H 118 >6BFG-A nrPDB Length = 399 Score = 123 bits (308), Expect = 2e-28, Method: Composition-based stats. Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 10/128 (7%) Query: 273 LDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICI 332 L S Q ++ F +++++D +P+ ++ G +++A A I G D + + G Sbjct: 222 LMSRQMDASFNWEALRWLRDLWPHKLLVKG-LLSAEDADRCIAEGADGVILSNHGG---- 276 Query: 333 TQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAA 392 L C + + +++ + G PV+ D G + I KALALGA V++G Sbjct: 277 --RQLDCA---ISPMEVLAQSVAKTGKPVLIDSGFRRGSDIVKALALGAEAVLLGRATLY 331 Query: 393 TTEAPGEY 400 A GE Sbjct: 332 GLAARGET 339 >2A85-A nrPDB Length = 380 Score = 122 bits (306), Expect = 3e-28, Method: Composition-based stats. Identities = 37/150 (24%), Positives = 65/150 (43%), Gaps = 15/150 (10%) Query: 251 GTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQA 310 G + +L QA L S Q ++ F +++++D +P+ ++ G +++A A Sbjct: 186 GIDLGKMDKANLEMQAA-----LMSRQMDASFNWEALRWLRDLWPHKLLVKG-LLSAEDA 239 Query: 311 KNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNV 370 I G D + + G L C + + +++ + G PV+ D G + Sbjct: 240 DRCIAEGADGVILSNHGG------RQLDCA---ISPMEVLAQSVAKTGKPVLIDSGFRRG 290 Query: 371 GHIAKALALGASTVMMGSLLAATTEAPGEY 400 I KALALGA V++G A GE Sbjct: 291 SDIVKALALGAEAVLLGRATLYGLAARGET 320 >4N6F-A nrPDB Length = 256 Score = 70.9 bits (172), Expect = 1e-12, Method: Composition-based stats. Identities = 38/159 (23%), Positives = 72/159 (45%), Gaps = 24/159 (15%) Query: 250 IGTHEDDKYRLDLLAQA-------GVDVVVLDSSQGNSI----FQINMIKYIKDKYPNLQ 298 IGT + + L A G++++ LD ++ + + ++ + ++ Sbjct: 81 IGTTSFARTKESALRSARILRDSLGIEILKLDVRGDDNTPDNAGTVEAARELRAE--GME 138 Query: 299 VIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFG 358 ++ + A A+ L +AG ALRV +A GR A + E + G Sbjct: 139 LLPFILPDLATARALEEAGCAALRVMASP---------VASGRGIANPA-AIRELIEQIG 188 Query: 359 VPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAP 397 +PV+ +GGI + H+A+A+ LGAS ++ + L E+P Sbjct: 189 IPVVVEGGIGSARHVAEAMELGASATLVNTALVR-AESP 226 >6DVI-A nrPDB Length = 394 Score = 67.8 bits (164), Expect = 1e-11, Method: Composition-based stats. Identities = 30/123 (24%), Positives = 50/123 (40%), Gaps = 10/123 (8%) Query: 278 GNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVL 337 G+S+ I +++ + VI + A+ +D+GVD + G Sbjct: 245 GHSV-TWEDIDWVRS-ITKMPVILKGIQHPDDARRAVDSGVDGIYCSNHGG------RQA 296 Query: 338 ACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAP 397 G P + +V + + PV+ D GI+ + KALA+GAS V +G A Sbjct: 297 NGGLPALDCLPEVVKASGDT--PVLFDSGIRTGADVVKALAMGASAVGIGRPYAWGAALG 354 Query: 398 GEY 400 G Sbjct: 355 GSK 357 >5ZBN-A nrPDB Length = 371 Score = 66.3 bits (160), Expect = 3e-11, Method: Composition-based stats. Identities = 29/116 (25%), Positives = 52/116 (44%), Gaps = 8/116 (6%) Query: 284 INMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQ 343 ++++ +L ++ V+TA A+ + AG + V L Sbjct: 214 WKDVQWL-QTITSLPILVKGVLTAEDARLAVQAGAAGIIVSNHGA------RQLDYVPST 266 Query: 344 ATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGE 399 A+ +V + A+ +PV DGG++ + KALALGAS + +G + + A GE Sbjct: 267 IMALEEVVKAAQG-RIPVFLDGGVRRGTDVFKALALGASGIFIGRPVVFSLAAEGE 321 >1AL8-A nrPDB Length = 359 Score = 62.8 bits (151), Expect = 4e-10, Method: Composition-based stats. Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 8/123 (6%) Query: 277 QGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEV 336 Q + + ++ +L ++ V+TA A+ + G + V Sbjct: 206 QIDRSLSWKDVAWL-QTITSLPILVKGVITAEDARLAVQHGAAGIIVSNHGA------RQ 258 Query: 337 LACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEA 396 L A+ +V + A+ +PV DGG++ + KALALGA+ V +G + + A Sbjct: 259 LDYVPATIMALEEVVKAAQG-RIPVFLDGGVRRGTDVFKALALGAAGVFIGRPVVFSLAA 317 Query: 397 PGE 399 GE Sbjct: 318 EGE 320 >2CDH-0 nrPDB Length = 226 Score = 61.2 bits (147), Expect = 1e-09, Method: Composition-based stats. Identities = 28/120 (23%), Positives = 52/120 (43%), Gaps = 8/120 (6%) Query: 280 SIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLAC 339 ++ + ++ +L ++ V+TA A+ + G + V L Sbjct: 93 ALTVWKDVAWL-QTITSLPILVKGVITAEDARLAVQHGAAGIIVSNHGA------RQLDY 145 Query: 340 GRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGE 399 A+ +V + A+ +PV DGG++ + KALALGA+ V +G + + A GE Sbjct: 146 VPATIMALEEVVKAAQG-RIPVFLDGGVRRGTDVFKALALGAAGVFIGRPVVFSLAAEGE 204 >2RDU-A nrPDB Length = 387 Score = 55.9 bits (133), Expect = 4e-08, Method: Composition-based stats. Identities = 26/118 (22%), Positives = 48/118 (40%), Gaps = 10/118 (8%) Query: 284 INMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRP- 342 IK+++ + +L ++ ++ A+ + G++ + V L G P Sbjct: 236 WEDIKWLR-RLTSLPIVAKGILRGDDAREAVKHGLNGILVSNHGA------RQLD-GVPA 287 Query: 343 QATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEY 400 + ++ E V V DGG++ + KALALGA V +G + GE Sbjct: 288 TIDVLPEIVEAVEG-KVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEK 344 >3SGZ-A nrPDB Length = 352 Score = 53.5 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 26/120 (21%), Positives = 45/120 (37%), Gaps = 8/120 (6%) Query: 280 SIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLAC 339 + F N + + L +I ++T A+ + V + V G L Sbjct: 202 ASFCWNDLSLL-QSITRLPIILKGILTKEDAELAMKHNVQGIVVSNHGG------RQLDE 254 Query: 340 GRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGE 399 A+ +V + + V DGG++ + KALALGA + +G + GE Sbjct: 255 VSASIDALREVVAAVKG-KIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGE 313 >2J6X-A nrPDB Length = 374 Score = 50.5 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 25/112 (22%), Positives = 40/112 (35%), Gaps = 8/112 (7%) Query: 287 IKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATA 346 I+ I + G + A I AG + V L Sbjct: 227 IEEIAAHSGLPVFVKG-IQHPEDADMAIKAGASGIWVSNHGA------RQLYEAPGSFDT 279 Query: 347 VYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPG 398 + ++E + VP++ D G++ H+AKALA GA V +G + G Sbjct: 280 LPAIAERVNK-RVPIVFDSGVRRGEHVAKALASGADVVALGRPVLFGLALGG 330 >2YVX-A nrPDB Length = 473 Score = 49.7 bits (117), Expect = 3e-06, Method: Composition-based stats. Identities = 31/141 (21%), Positives = 51/141 (36%), Gaps = 18/141 (12%) Query: 102 NEVRKVKKYE---QGFITDP--VVLSPKDRVRDVFEAKAR-----HGFCGIPITDTGRMG 151 EV + +YE G + P V + V +V R I + D Sbjct: 144 AEVEALARYEEDEAGGLMTPEYVAVREGMTVEEVLRFLRRAAPDAETIYYIYVVDE---K 200 Query: 152 SRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPI 211 RL G++S RD+ + EIM +V +E ++ LP+ Sbjct: 201 GRLKGVLSLRDLIVADPRTR---VAEIMNP--KVVYVRTDTDQEEVARLMADYDFTVLPV 255 Query: 212 VNEDDELVAIIARTDLKKNRD 232 V+E+ LV I+ D+ + Sbjct: 256 VDEEGRLVGIVTVDDVLDVLE 276 >1TYG-A nrPDB Length = 253 Score = 48.9 bits (115), Expect = 5e-06, Method: Composition-based stats. Identities = 21/86 (24%), Positives = 37/86 (43%), Gaps = 10/86 (11%) Query: 310 AKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQN 369 A+ L + GV A+ G + G+ + +S + VPVI D GI + Sbjct: 138 ARKLEELGVHAIMPGASP---------IGSGQGILNPL-NLSFIIEQAKVPVIVDAGIGS 187 Query: 370 VGHIAKALALGASTVMMGSLLAATTE 395 A A+ LGA V++ + ++ + Sbjct: 188 PKDAAYAMELGADGVLLNTAVSGADD 213 >1WV2-A nrPDB Length = 265 Score = 48.5 bits (114), Expect = 6e-06, Method: Composition-based stats. Identities = 25/127 (19%), Positives = 49/127 (38%), Gaps = 19/127 (14%) Query: 277 QGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALR------------VG 324 G+++ ++ ++ K +PN+ V T A+ L+ G D + Sbjct: 101 DGHNLVKLEVLADQKTLFPNV------VETLKAAEQLVKDGFDVMVYTSDDPIIARQLAE 154 Query: 325 MGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTV 384 +G ++ ++ G Y + VPV+ D G+ A A+ LG V Sbjct: 155 IGCIAVMPLAGLIGSGLGICNP-YNLRIILEEAKVPVLVDAGVGTASDAAIAMELGCEAV 213 Query: 385 MMGSLLA 391 +M + +A Sbjct: 214 LMNTAIA 220 >2YVZ-A nrPDB Length = 278 Score = 48.5 bits (114), Expect = 7e-06, Method: Composition-based stats. Identities = 31/141 (21%), Positives = 51/141 (36%), Gaps = 18/141 (12%) Query: 102 NEVRKVKKYE---QGFITDP--VVLSPKDRVRDVFEAKAR-----HGFCGIPITDTGRMG 151 EV + +YE G + P V + V +V R I + D Sbjct: 124 AEVEALARYEEDEAGGLMTPEYVAVREGMTVEEVLRFLRRAAPDAETIYYIYVVDE---K 180 Query: 152 SRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPI 211 RL G++S RD+ + EIM +V +E ++ LP+ Sbjct: 181 GRLKGVLSLRDLIVADPRTR---VAEIMNP--KVVYVRTDTDQEEVARLMADYDFTVLPV 235 Query: 212 VNEDDELVAIIARTDLKKNRD 232 V+E+ LV I+ D+ + Sbjct: 236 VDEEGRLVGIVTVDDVLDVLE 256 >5ZKN-A nrPDB Length = 241 Score = 47.8 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 30/138 (21%), Positives = 57/138 (41%), Gaps = 13/138 (9%) Query: 256 DKYRLDLLAQAGVDVVVLDSSQ---GNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKN 312 ++ L GV ++ +D+++ + N I IK+KYPN + ++ + +A Sbjct: 99 TIKEVEDLINEGVQIIAIDATKRERPDRKDLKNFIAEIKEKYPNQLFMA-DISSVDEALY 157 Query: 313 LIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGH 372 G D + T A+ ++ + + +PVIA+G I Sbjct: 158 AEKIGFDIV---------GTTLVGYTDYTKNYKALEELKKVVKVVKIPVIAEGNIDTPLK 208 Query: 373 IAKALALGASTVMMGSLL 390 KAL +GA V++G + Sbjct: 209 AKKALEIGAFAVVVGGAI 226 >3BW4-A nrPDB Length = 369 Score = 47.0 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 29/96 (30%), Positives = 43/96 (44%), Gaps = 8/96 (8%) Query: 306 TAAQAKNLIDAGVDALRV-----GMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVP 360 T +A+ + AG DA+ G G+ + E G + + +V E +P Sbjct: 154 TPEEARAVEAAGADAVIAQGVEAGGHQGTHRDSSEDDGAGIGLLSLLAQVREAVD---IP 210 Query: 361 VIADGGIQNVGHIAKALALGASTVMMGSLLAATTEA 396 V+A GGI G IA LA GA +G+ AT E+ Sbjct: 211 VVAAGGIMRGGQIAAVLAAGADAAQLGTAFLATDES 246 >1SZG-A nrPDB Length = 511 Score = 46.6 bits (109), Expect = 3e-05, Method: Composition-based stats. Identities = 25/120 (20%), Positives = 38/120 (31%), Gaps = 11/120 (9%) Query: 284 INMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQ 343 I+ +K K VI G V + GV + + G L R Sbjct: 332 WKDIEELKKKTKLPIVIKG-VQRTEDVIKAAEIGVSGVVLSNHGG------RQLDFSRAP 384 Query: 344 ATAVYKVSEYARRFGVP----VIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGE 399 + + + + V DGG++ + KAL LGA V +G G Sbjct: 385 IEVLAETMPILEQRNLKDKLEVFVDGGVRRGTDVLKALCLGAKGVGLGRPFLYANSCYGR 444 >1QCW-A nrPDB Length = 410 Score = 46.2 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 25/120 (20%), Positives = 38/120 (31%), Gaps = 11/120 (9%) Query: 284 INMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQ 343 I+ +K K VI G V + GV + + G L R Sbjct: 231 WKDIEELKKKTKLPIVIKG-VQRTEDVIKAAEIGVSGVVLSNHGG------RQLDFSRAP 283 Query: 344 ATAVYKVSEYARRFGVP----VIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGE 399 + + + + V DGG++ + KAL LGA V +G G Sbjct: 284 IEVLAETMPILEQRNLKDKLEVFVDGGVRRGTDVLKALCLGAKGVGLGRPFLYANSCYGR 343 >4Q4K-A nrPDB Length = 357 Score = 45.8 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 30/96 (31%), Positives = 40/96 (41%), Gaps = 10/96 (10%) Query: 306 TAAQAKNLIDAGVDAL-----RVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVP 360 T +A + AG DA+ G G + A G + V A R +P Sbjct: 158 TPEEAALVEAAGADAVVAQGIEAGGHRGVFEPERGDAAIGT-----LALVRLLAARGSLP 212 Query: 361 VIADGGIQNVGHIAKALALGASTVMMGSLLAATTEA 396 V+A GGI + I AL LGAS V MG+ E+ Sbjct: 213 VVAAGGIMDGRGIRAALELGASAVQMGTAFVLCPES 248 Score = 32.7 bits (73), Expect = 0.42, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 35/72 (48%), Gaps = 5/72 (6%) Query: 51 LTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQ-ANEVRKVKK 109 +T T+ + ++ P++ +PM V+ +A A++ GG+G I + + +R+V+ Sbjct: 1 MTDRFTRLLGIQQPIIQAPMLGVSTPALAAAVSNAGGLGSIAITGSAAEKGRALIREVR- 59 Query: 110 YEQGFITDPVVL 121 G P + Sbjct: 60 ---GLTDKPFNV 68 >2GJN-A nrPDB Length = 328 Score = 45.1 bits (105), Expect = 8e-05, Method: Composition-based stats. Identities = 21/58 (36%), Positives = 28/58 (48%) Query: 340 GRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAP 397 G + + A R VP+IA GG + + ALALGA + MG+ AT E P Sbjct: 154 GEDDIPGLVLLPAAANRLRVPIIASGGFADGRGLVAALALGADAINMGTRFLATRECP 211 >1P0K-A nrPDB Length = 349 Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 30/130 (23%), Positives = 52/130 (40%), Gaps = 10/130 (7%) Query: 281 IFQINMIKYI--KDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGS-------IC 331 + I+ I + P + G ++ A A L +AG A+ +G G+ + Sbjct: 164 SGALKRIEQICSRVSVPVIVKEVGFGMSKASAGKLYEAGAAAVDIGGYGGTNFSKIENLR 223 Query: 332 ITQEVLACGRPQATAVYKVSEYARRF-GVPVIADGGIQNVGHIAKALALGASTVMMGSLL 390 +++ + ++E F +IA GG+Q+ +AKA+ALGAS M Sbjct: 224 RQRQISFFNSWGISTAASLAEIRSEFPASTMIASGGLQDALDVAKAIALGASCTGMAGHF 283 Query: 391 AATTEAPGEY 400 GE Sbjct: 284 LKALTDSGEE 293 >6B2E-C nrPDB Length = 336 Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 30/157 (19%), Positives = 64/157 (40%), Gaps = 19/157 (12%) Query: 88 IGFIHHN-CTPEFQANEV--RKVKKYEQGFITDP----VVLSPKDRVRDVFEAKARHGFC 140 I +H + Q E+ K++ + + ++ D V +SP + D + R+ Sbjct: 97 INILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIH 156 Query: 141 GIPITDTGRMGSRLVGIISSRDI---------DFLKEEEHDCFLEEI-MTKREDLVVAPA 190 +P+ D + I++ + I +F K E LEE+ + ++ + Sbjct: 157 RLPVIDPES--GNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRT 214 Query: 191 GITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDL 227 + A I + + LP+V+E +V I ++ D+ Sbjct: 215 TTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDV 251 Score = 37.0 bits (84), Expect = 0.021, Method: Composition-based stats. Identities = 31/149 (20%), Positives = 60/149 (40%), Gaps = 14/149 (9%) Query: 90 FIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGR 149 FI PEF + + +++ I +P V +H +P+ D Sbjct: 184 FITEFPKPEFMSKSLEELQIGTYANIAMVRTTTP---VYVALGIFVQHRVSALPVVDE-- 238 Query: 150 MGSRLVGIISSRDIDFLKEEEHDCFLEEIMTK--------REDLVVAPAGITLKEANEIL 201 R+V I S D+ L E+ L+ +TK E ++ TL+ L Sbjct: 239 -KGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRL 297 Query: 202 QRSKKGKLPIVNEDDELVAIIARTDLKKN 230 ++ +L +V+E+D + I++ +D+ + Sbjct: 298 VEAEVHRLVVVDENDVVKGIVSLSDILQA 326 >5Z9Y-A nrPDB Length = 252 Score = 42.4 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 26/123 (21%), Positives = 41/123 (33%), Gaps = 22/123 (17%) Query: 310 AKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQN 369 A+ L D G A+ + +GS + G A + + VPV+ D GI Sbjct: 140 ARRLEDTGCAAV-MPLGSP--------IGTGLGIANP-HNIEMIVAGARVPVVLDAGIGT 189 Query: 370 VGHIAKALALGASTVMMGSLLAATTE------------APGEYFFSDGIRLKKYRGMGSL 417 A A+ LG V++ S + + G G K++ S Sbjct: 190 ASDAALAMELGCDAVLLASAVTRAADPPAMAAAMAAAVTAGYLARCAGRIPKRFWAQASS 249 Query: 418 DAM 420 A Sbjct: 250 PAR 252 >2Z6J-A nrPDB Length = 332 Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 33/137 (24%), Positives = 52/137 (37%), Gaps = 17/137 (12%) Query: 260 LDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVD 319 +DL+ + GV VV + GN + ++ V + A AK + G D Sbjct: 81 VDLVIEEGVKVVT--TGAGNPSKYMERFHEAG------IIVIPVVPSVALAKRMEKIGAD 132 Query: 320 ALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALAL 379 A+ + G + T + V + A +PVIA GGI + A L Sbjct: 133 AV---IAEG------MEAGGHIGKLTTMTLVRQVATAISIPVIAAGGIADGEGAAAGFML 183 Query: 380 GASTVMMGSLLAATTEA 396 GA V +G+ E+ Sbjct: 184 GAEAVQVGTRFVVAKES 200 >1VHN-A nrPDB Length = 318 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 29/153 (18%), Positives = 52/153 (33%), Gaps = 14/153 (9%) Query: 186 VVAPAGITLKEANEILQRSKK-----GKLPIVNEDDELVAIIARTDLKKNRDYPLAS-KD 239 + L EA IL K P+ E DL+ R K Sbjct: 65 IFGSEPNELSEAARILSEKYKWIDLNAGCPVRKVVKEGAGGALLKDLRHFRYIVRELRKS 124 Query: 240 AKKQLLCGAAIGTHEDDKYRL-DLLAQAGVDVVVLDSSQGNSIFQ----INMIKYIKDKY 294 + +G +++ + +L + GVD V + + F + ++ + Sbjct: 125 VSGKFSVKTRLGWEKNEVEEIYRILVEEGVDEVFIHTRTVVQSFTGRAEWKALSVLEKRI 184 Query: 295 PNLQVIGGNVVTAAQA-KNLIDAGVDALRVGMG 326 P + G++ T A + L ++G D L V G Sbjct: 185 P--TFVSGDIFTPEDAKRALEESGCDGLLVARG 215 >3TE5-C nrPDB Length = 323 Score = 39.7 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 31/209 (14%), Positives = 78/209 (37%), Gaps = 24/209 (11%) Query: 43 DFTA---DQVDLTSALTKKITLKT----PLVSSPMDTVTEAGMAIAMALTGGIGFIHHNC 95 D + L ++L K +L +VS+P+ + A + T I I + Sbjct: 34 DVLPVSYRLIVLDTSLLVKKSLNVLLQNSIVSAPLWDSKTSRFAGLLTTTDFINVIQYYF 93 Query: 96 TPEFQANEVRKV-----KKYEQGFITDPV---VLSPKDRVRDVFEAKARHGFCGIPITDT 147 + + V K+ K E+ D + + P + + IP+ D Sbjct: 94 SNPDKFELVDKLQLDGLKDIERALGVDQLDTASIHPSRPLFEACLKMLESRSGRIPLIDQ 153 Query: 148 GRMGSR--LVGIISS-RDIDFLKEEEHDC-----FLEEI-MTKREDLVVAPAGITLKEAN 198 R +V +++ R + F+ + + ++ + ++++ + + Sbjct: 154 DEETHREIVVSVLTQYRILKFVALNCRETHFLKIPIGDLNIITQDNMKSCQMTTPVIDVI 213 Query: 199 EILQRSKKGKLPIVNEDDELVAIIARTDL 227 ++L + + +PI++E+ L+ + D+ Sbjct: 214 QMLTQGRVSSVPIIDENGYLINVYEAYDV 242 >4JEJ-A nrPDB Length = 244 Score = 38.9 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 26/54 (48%) Query: 337 LACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLL 390 G + + +S ++ +P+I GGI ++ I KA GA V++G+ Sbjct: 181 AGSGAKKPVPLEMISVISQNVEIPIIVGGGIVDLHGIKKAYNAGADLVVIGTAF 234 >1EP3-A nrPDB Length = 311 Score = 38.5 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 34/91 (37%), Gaps = 11/91 (12%) Query: 310 AKNLIDAGVDA---------LRVGMGSGSICITQEVLACGRPQATAVYK--VSEYARRFG 358 AK + AG D +R + + + P V + + A+ Sbjct: 182 AKAVEAAGADGLTMINTLMGVRFDLKTRQPILANITGGLSGPAIKPVALKLIHQVAQDVD 241 Query: 359 VPVIADGGIQNVGHIAKALALGASTVMMGSL 389 +P+I GG+ N + + GAS V +G+ Sbjct: 242 IPIIGMGGVANAQDVLEMYMAGASAVAVGTA 272 >5UE9-A nrPDB Length = 306 Score = 38.1 bits (87), Expect = 0.009, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 35/91 (38%), Gaps = 11/91 (12%) Query: 310 AKNLIDAGVDA---------LRVGMGSGSICITQEVLACGRPQATAVYK--VSEYARRFG 358 AK + AG D +R + + + P V + + A+ Sbjct: 178 AKAVEAAGADGLTMINTLMGVRFDLKTRKPVLANITGGLSGPAIKPVALKLIHQVAQVVD 237 Query: 359 VPVIADGGIQNVGHIAKALALGASTVMMGSL 389 +P+I GG+++ + + GAS V +G+ Sbjct: 238 IPIIGMGGVESAQDVLEMYMAGASAVAVGTA 268 >5LSM-A nrPDB Length = 359 Score = 38.1 bits (87), Expect = 0.010, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 34/104 (32%), Gaps = 10/104 (9%) Query: 306 TAAQAKNLIDAGVDALRV-----GMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVP 360 T +A L G DA+ G G G + +P Sbjct: 157 TVEEALWLEARGADAIIAQGLEAGGHRGHFLSEDLTEQLGTFSLLP-----QIIAAVEIP 211 Query: 361 VIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSD 404 VIA GGI + + A+ +GAS V +G+ E + Sbjct: 212 VIAAGGIVDATTVRAAMTMGASAVQVGTAYLLCPECNTSAIHRE 255 Score = 36.6 bits (83), Expect = 0.029, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 24/38 (63%) Query: 54 ALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFI 91 LT+ ++ P++ +PM V + +AIA++ GG+G + Sbjct: 4 RLTRLFGIEFPIIQAPMAGVQGSALAIAVSEAGGLGSL 41 >4HG0-A nrPDB Length = 292 Score = 38.1 bits (87), Expect = 0.010, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 1/68 (1%) Query: 161 RDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNED-DELV 219 RD+ + D + +IM R ++ TL E +++ S + P+++ED D + Sbjct: 55 RDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIE 114 Query: 220 AIIARTDL 227 I+ DL Sbjct: 115 GILMAKDL 122 >1RPX-A nrPDB Length = 230 Score = 37.7 bits (86), Expect = 0.012, Method: Composition-based stats. Identities = 28/138 (20%), Positives = 51/138 (36%), Gaps = 10/138 (7%) Query: 258 YRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAG 317 R+ +AG D+V + Q ++I I IK V+ N T A + Sbjct: 82 QRVPDFIKAGADIVSVHCEQSSTIHLHRTINQIKSLGAKAGVVL-NPGTPLTAIEYVLDA 140 Query: 318 VD-ALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVP--VIADGGIQNVGHIA 374 VD L + + G + Q + + + G+ + DGG+ + Sbjct: 141 VDLVLIMSVNPGFGGQSFIES-----QVKKISDLRKICAERGLNPWIEVDGGVG-PKNAY 194 Query: 375 KALALGASTVMMGSLLAA 392 K + GA+ ++ GS + Sbjct: 195 KVIEAGANALVAGSAVFG 212 >3PC3-A nrPDB Length = 527 Score = 37.0 bits (84), Expect = 0.018, Method: Composition-based stats. Identities = 8/41 (19%), Positives = 17/41 (41%), Gaps = 2/41 (4%) Query: 118 PVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGII 158 PV+L V + +H +P+ D ++G++ Sbjct: 395 PVILKSDATVGEAIALMKKHRVDQLPVVDQD--DGSVLGVV 433 Score = 29.7 bits (65), Expect = 3.7, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 22/34 (64%) Query: 186 VVAPAGITLKEANEILQRSKKGKLPIVNEDDELV 219 V+ + T+ EA ++++ + +LP+V++DD V Sbjct: 396 VILKSDATVGEAIALMKKHRVDQLPVVDQDDGSV 429 >5GVH-A nrPDB Length = 314 Score = 37.0 bits (84), Expect = 0.019, Method: Composition-based stats. Identities = 35/110 (31%), Positives = 53/110 (48%), Gaps = 11/110 (10%) Query: 288 KYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRV-GMGSGSICITQEVLACGRPQATA 346 KYI++ N + V + + A+ + AG DA+ GM SG + T Sbjct: 103 KYIRELKENGTKVIPVVASDSLARMVERAGADAVIAEGMESGGH----------IGEVTT 152 Query: 347 VYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEA 396 V++ +R +PVIA GGI + +A A ALGA V MG+ A+ E+ Sbjct: 153 FVLVNKVSRSVNIPVIAAGGIADGRGMAAAFALGAEAVQMGTRFVASVES 202 >2HTM-A nrPDB Length = 268 Score = 37.0 bits (84), Expect = 0.022, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 48/110 (43%), Gaps = 11/110 (10%) Query: 288 KYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAV 347 + I++ + L +G ++V A + L A V L +GSG T+ A+ Sbjct: 119 RLIEEDFLVLPYMGPDLVLAKRLAALGTATVMPLAAPIGSGWGVRTR-----------AL 167 Query: 348 YKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAP 397 ++ + PV+ D G+ H A+ + LG V++ + +A + P Sbjct: 168 LELFAREKASLPPVVVDAGLGLPSHAAEVMELGLDAVLVNTAIAEAQDPP 217 >1MXS-A nrPDB Length = 225 Score = 37.0 bits (84), Expect = 0.023, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 33/82 (40%), Gaps = 3/82 (3%) Query: 240 AKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQV 299 K ++L I ED D LA G+ + + S + I+ ++++ P L V Sbjct: 24 EKARILPVITIAREEDILPLADALAAGGIRTLEVTLR---SQHGLKAIQVLREQRPELCV 80 Query: 300 IGGNVVTAAQAKNLIDAGVDAL 321 G V+ + + AG + Sbjct: 81 GAGTVLDRSMFAAVEAAGAQFV 102 >1KA9-F nrPDB Length = 252 Score = 36.2 bits (82), Expect = 0.034, Method: Composition-based stats. Identities = 32/151 (21%), Positives = 54/151 (35%), Gaps = 22/151 (14%) Query: 242 KQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSS-------------QGNSIFQINMI- 287 +++ +G L +G D V ++S+ + + I Sbjct: 72 ERVFIPLTVGGGVRSLEDARKLLLSGADKVSVNSAAVRRPELIRELADHFGAQAVVLAID 131 Query: 288 -KYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATA 346 ++ + +P + V GG V T A G V +G+G I +T G + Sbjct: 132 ARW-RGDFPEVHVAGGRVPTGLHAVEWAVKG-----VELGAGEILLTSMDRD-GTKEGYD 184 Query: 347 VYKVSEYARRFGVPVIADGGIQNVGHIAKAL 377 + A GVPVIA GG + H +A Sbjct: 185 LRLTRMVAEAVGVPVIASGGAGRMEHFLEAF 215 Score = 33.1 bits (74), Expect = 0.27, Method: Composition-based stats. Identities = 26/112 (23%), Positives = 41/112 (36%), Gaps = 23/112 (20%) Query: 291 KDKYPNLQVIGGNVVTA-------------AQAKNLIDAGVDALRVGMGSGSICITQEVL 337 K P L V G VV A+ +AG D L + ++ Sbjct: 5 KRIVPCLDVHAGRVVKGVNFVNLRDAGDPVEAARAYDEAGADEL----------VFLDIS 54 Query: 338 ACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSL 389 A +A + V+ A R +P+ GG++++ K L GA V + S Sbjct: 55 ATHEERAILLDVVARVAERVFIPLTVGGGVRSLEDARKLLLSGADKVSVNSA 106 >2UV7-A nrPDB Length = 152 Score = 35.4 bits (80), Expect = 0.052, Method: Composition-based stats. Identities = 25/136 (18%), Positives = 55/136 (40%), Gaps = 11/136 (8%) Query: 103 EVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRD 162 + +++ + G + ++ V +H +P+ D R+V I S D Sbjct: 16 MSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDE---KGRVVDIYSKFD 72 Query: 163 IDFLKEEEHDCFLEEIMTK--------REDLVVAPAGITLKEANEILQRSKKGKLPIVNE 214 + L E+ L+ +TK E ++ TL+ L ++ L +V+E Sbjct: 73 VINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHGLVVVDE 132 Query: 215 DDELVAIIARTDLKKN 230 +D + I++ +D+ + Sbjct: 133 NDVVKGIVSLSDILQA 148 Score = 31.2 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 30/65 (46%), Gaps = 1/65 (1%) Query: 164 DFLKEEEHDCFLEEI-MTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAII 222 +F K E LEE+ + ++ + + A I + + LP+V+E +V I Sbjct: 9 EFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIY 68 Query: 223 ARTDL 227 ++ D+ Sbjct: 69 SKFDV 73 >2GGG-A nrPDB Length = 375 Score = 35.4 bits (80), Expect = 0.059, Method: Composition-based stats. Identities = 35/151 (23%), Positives = 63/151 (41%), Gaps = 24/151 (15%) Query: 241 KKQLLCGAAIGTHEDDKYRLDLL---AQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNL 297 K+Q+ G ++G D++ +DL+ + G + L G + + ++ ++ +P++ Sbjct: 134 KEQVEVGVSLGIQADEQATVDLVRRHVEQGYRRIKLKIKPG---WDVQPVRATREAFPDI 190 Query: 298 QVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKV---SEYA 354 ++ V A A L DAG + E Q A + +E A Sbjct: 191 RL----TVDANSAYTLADAG-----------RLRQLDEYDLTYIEQPLAWDDLVDHAELA 235 Query: 355 RRFGVPVIADGGIQNVGHIAKALALGASTVM 385 RR P+ D + + KALALGA V+ Sbjct: 236 RRIRTPLCLDESVASASDARKALALGAGGVI 266 >1VHC-A nrPDB Length = 224 Score = 35.4 bits (80), Expect = 0.066, Method: Composition-based stats. Identities = 28/136 (20%), Positives = 50/136 (36%), Gaps = 13/136 (9%) Query: 248 AAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTA 307 A+ +D D LA+ G+ V + S + I+ ++ P+ + G V+TA Sbjct: 23 IALDNADDILPLADTLAKNGLSVAEITFR---SEAAADAIRLLRANRPDFLIAAGTVLTA 79 Query: 308 AQAKNLIDAGVDALRV-GMGSGSICITQ-----EVLACGRPQATAVYKVSEYARRFGVPV 361 Q +G D + G+ + + Q P A + + P Sbjct: 80 EQVVLAKSSGADFVVTPGLNPKIVKLCQDLNFPITPGVNNPMAIEIALEMGISAVKFFPA 139 Query: 362 IADGGIQNVGHIAKAL 377 A GG++ + KAL Sbjct: 140 EASGGVK----MIKAL 151 >4EVZ-A nrPDB Length = 258 Score = 35.1 bits (79), Expect = 0.068, Method: Composition-based stats. Identities = 30/120 (25%), Positives = 46/120 (38%), Gaps = 3/120 (2%) Query: 291 KDKYPNLQVIGGNVVTAAQAKNLIDAGVD---ALRVGMGSGSICITQEVLACGRPQATAV 347 K P L V G VV +NL DAG A R + ++ A + T + Sbjct: 4 KRIIPCLDVKDGRVVKGVNFENLRDAGDPVELAARYDEEGADELVFLDITASHEGRETML 63 Query: 348 YKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIR 407 V A + +P+ GGI++V ++ L GA V + + E E G + Sbjct: 64 EVVERTAEQVFIPLTVGGGIRSVEDASRLLRAGADKVSINTAAVKNPELITEAAEEFGSQ 123 Score = 33.1 bits (74), Expect = 0.31, Method: Composition-based stats. Identities = 35/185 (18%), Positives = 65/185 (35%), Gaps = 22/185 (11%) Query: 242 KQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIG 301 +Q+ +G L +AG D V ++++ ++ +I +++ + V+ Sbjct: 71 EQVFIPLTVGGGIRSVEDASRLLRAGADKVSINTA---AVKNPELITEAAEEFGSQAVVV 127 Query: 302 GNVVTAAQAKNLIDA-------GVDALR-----VGMGSGSICITQEVLACGRPQATAVYK 349 + G+DA+ V +G+G I +T G + Sbjct: 128 AIDAKRVGGGWEVFTHGGRKPTGLDAVEWARKVVELGAGEILLTSMDRD-GTKAGYDLEL 186 Query: 350 VSEYARRFGVPVIADGGIQNVGHIAKALAL-GASTVMMGSLLAATTEAPGEYFFSDGIRL 408 + VPVIA GG + H A+ L GA + S+ GE + Sbjct: 187 TRAVSEAVSVPVIASGGAGELEHFAEVFELEGADAALAASIFHF-----GEITIREVKAY 241 Query: 409 KKYRG 413 + RG Sbjct: 242 LRERG 246 >2ZRW-A nrPDB Length = 368 Score = 34.7 bits (78), Expect = 0.092, Method: Composition-based stats. Identities = 38/163 (23%), Positives = 62/163 (38%), Gaps = 36/163 (22%) Query: 251 GTHEDDKYRLDLLAQAGVDVVVLDSSQ------GNSIFQINMIKYIKDKYPNLQVI---- 300 G + + +A V L+ +Q G +QI ++ ++D L V Sbjct: 134 GYGLKEFQDAIQMIEADAIAVHLNPAQEVFQPEGEPEYQIYALEKLRDISKELSVPIIVK 193 Query: 301 -GGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEV-----------------LACGRP 342 GN ++ AK L G+ G+ I E+ L G P Sbjct: 194 ESGNGISMETAKLLYSYGIKNFDTSGQGGTNWIAIEMIRDIRRGNWKAESAKNFLDWGVP 253 Query: 343 QATAVYKVSEYARRFGVP---VIADGGIQNVGHIAKALALGAS 382 A ++ +V R+ VP ++ GGI++ AKA+ALGA Sbjct: 254 TAASIMEV-----RYSVPDSFLVGSGGIRSGLDAAKAIALGAD 291 >3IGS-A nrPDB Length = 232 Score = 34.7 bits (78), Expect = 0.098, Method: Composition-based stats. Identities = 24/135 (17%), Positives = 47/135 (34%), Gaps = 11/135 (8%) Query: 260 LDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVD 319 +D LAQAG ++ +D + + + + + + + + + G D Sbjct: 94 VDALAQAGAAIIAVDGTARQRPVAVEAL--LARIHHHHLLTMADCSSVDDGLACQRLGAD 151 Query: 320 ALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALAL 379 + M + T E + + G VIA+G + A+A+ Sbjct: 152 IIGTTMSGYTTPDTPEE---------PDLPLVKALHDAGCRVIAEGRYNSPALAAEAIRY 202 Query: 380 GASTVMMGSLLAATT 394 GA V +GS + Sbjct: 203 GAWAVTVGSAITRLE 217 >4MM1-A nrPDB Length = 250 Score = 34.7 bits (78), Expect = 0.10, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 31/81 (38%), Gaps = 7/81 (8%) Query: 337 LACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEA 396 G P+ ++ R +I GGI++ A+ GA V+ G+++ + Sbjct: 175 AGSGAPEHVPEEMIALVKRCTDQILIVGGGIRSGEDAARVAGAGADVVVTGTVVENSDN- 233 Query: 397 PGEYFFSDGIRLKKYRGMGSL 417 + + GMGS+ Sbjct: 234 ------VEDKIREIVEGMGSV 248 Score = 29.7 bits (65), Expect = 2.9, Method: Composition-based stats. Identities = 10/40 (25%), Positives = 18/40 (45%) Query: 285 NMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVG 324 MI +K + ++GG + + A + AG D + G Sbjct: 186 EMIALVKRCTDQILIVGGGIRSGEDAARVAGAGADVVVTG 225 >3SR7-A nrPDB Length = 365 Score = 34.7 bits (78), Expect = 0.11, Method: Composition-based stats. Identities = 16/50 (32%), Positives = 24/50 (48%) Query: 342 PQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLA 391 Q TA ++ V ++A GGI++ I KAL LGA V + + Sbjct: 262 GQTTAQVLLNAQPLMDKVEILASGGIRHPLDIIKALVLGAKAVGLSRTML 311 >2L6D-A nrPDB Length = 110 Score = 33.9 bits (76), Expect = 0.18, Method: Composition-based stats. Identities = 26/102 (25%), Positives = 39/102 (38%), Gaps = 7/102 (6%) Query: 66 VSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKD 125 +S+ D TEAGMA L+ I F H N P + E K ++ P V Sbjct: 1 MSAIRDITTEAGMAHFEGLSDAIVFFHKNLCPHCKNME----KVLDKFGARAPQVAISSV 56 Query: 126 RVRDVFEAKARHGFCGIPI---TDTGRMGSRLVGIISSRDID 164 E GF +P G++ GI++ R++ Sbjct: 57 DSEARPELMKELGFERVPTLVFIRDGKVAKVFSGIMNPRELQ 98 >1XI3-A nrPDB Length = 215 Score = 33.5 bits (75), Expect = 0.20, Method: Composition-based stats. Identities = 25/139 (17%), Positives = 50/139 (35%), Gaps = 8/139 (5%) Query: 264 AQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRV 323 VDV + + G + +M + + +IG +V + +A G D L Sbjct: 75 VDDRVDVALAVDADGVQLGPEDMPIEVAKEIAPNLIIGASVYSLEEALEAEKKGADYL-- 132 Query: 324 GMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGAST 383 G+GS+ T+ + + + + +PV+A GGI + + L G Sbjct: 133 --GAGSVFPTKTKEDA---RVIGLEGLRKIVESVKIPVVAIGGINKD-NAREVLKTGVDG 186 Query: 384 VMMGSLLAATTEAPGEYFF 402 + + S + + Sbjct: 187 IAVISAVMGAEDVRKATEE 205 >4XBS-A nrPDB Length = 265 Score = 33.5 bits (75), Expect = 0.22, Method: Composition-based stats. Identities = 30/166 (18%), Positives = 58/166 (34%), Gaps = 5/166 (3%) Query: 163 IDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAII 222 I F+ E+ + I L + EA + + + + +V EL Sbjct: 84 IPFVTEQLKGTDVNPIAVVGFPLGAMATESKIFEATTAIDQGAEE-IDMVLNVGELKGGN 142 Query: 223 ARTDLKKNRDYPLASKDAKKQLLCGAAIGT-HEDDKYRLDLLAQ-AGVDVVVLDSSQGNS 280 L + A K L +D+ R L++ AG D V + S Sbjct: 143 DEKVLADIQGLADAVHAKGKILKVILENALLTKDEIVRACQLSEKAGADFVKTSTGFSTS 202 Query: 281 IFQINMIKYIKDKYPNLQVIG--GNVVTAAQAKNLIDAGVDALRVG 324 ++ +K +++ + + G + + +A +IDAG + V Sbjct: 203 GAKVEDVKLMRETVGDRLGVKASGGIHSREEALAMIDAGASRMGVS 248 >4X2R-A nrPDB Length = 250 Score = 33.5 bits (75), Expect = 0.24, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 34/82 (41%), Gaps = 11/82 (13%) Query: 308 AQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGI 367 A++ ++AG + + + A GR + + G+ V GGI Sbjct: 37 EAARDWVEAGAEWIHL---------VDLDAAFGRGSNAPLLE--RIVGEVGIKVELSGGI 85 Query: 368 QNVGHIAKALALGASTVMMGSL 389 ++ + +AL GA+ V +G+ Sbjct: 86 RDDASLTRALKAGAARVNLGTA 107 >4WD0-A nrPDB Length = 250 Score = 33.5 bits (75), Expect = 0.24, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 31/83 (37%), Gaps = 6/83 (7%) Query: 331 CITQEVLAC---GRPQATAVYKVSEYARRFGVPVIADGGIQNVGH---IAKALALGASTV 384 C V G Q V + + + G PV+A GGI ++ + + + LG Sbjct: 168 CARYVVTDVTKDGTLQGPNVELLRQMVEKTGKPVVASGGISSLEDLRVLRELVPLGVEGA 227 Query: 385 MMGSLLAATTEAPGEYFFSDGIR 407 ++G L A E G R Sbjct: 228 IVGKALYAGAFTLPEALDVAGRR 250 >2ZBT-A nrPDB Length = 297 Score = 32.7 bits (73), Expect = 0.34, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 33/83 (39%), Gaps = 5/83 (6%) Query: 285 NMIKYIKDK--YPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMG---SGSICITQEVLAC 339 ++K++ D P + G + T A A ++ G+D + VG G SG + Sbjct: 197 ELVKWVHDHGRLPVVNFAAGGIATPADAALMMHLGMDGVFVGSGIFKSGDPRKRARAIVR 256 Query: 340 GRPQATAVYKVSEYARRFGVPVI 362 ++E + G P++ Sbjct: 257 AVAHYNDPEVLAEVSEDLGEPMV 279 >3O07-A nrPDB Length = 291 Score = 32.7 bits (73), Expect = 0.38, Method: Composition-based stats. Identities = 14/36 (38%), Positives = 17/36 (47%) Query: 291 KDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMG 326 K K P + G V T A A L+ G D + VG G Sbjct: 196 KGKLPVVNFAAGGVATPADAALLMQLGCDGVFVGSG 231 >4COO-A nrPDB Length = 563 Score = 32.7 bits (73), Expect = 0.39, Method: Composition-based stats. Identities = 8/51 (15%), Positives = 21/51 (41%), Gaps = 3/51 (5%) Query: 109 KYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIIS 159 + ++ ++ P+ + P E GF P+ D ++G+++ Sbjct: 435 RVQELGLSAPLTVLPTITCGHTIEILREKGFDQAPVVDEA---GVILGMVT 482 >5CSS-A nrPDB Length = 226 Score = 32.7 bits (73), Expect = 0.40, Method: Composition-based stats. Identities = 14/85 (16%), Positives = 34/85 (40%), Gaps = 4/85 (4%) Query: 304 VVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIA 363 V A +AK + D + + ++ +P+ + + + G V+ Sbjct: 119 VENAEEAKYFREYEPDFI--AYEPRDLIGGDVSVSTAKPEI--IEDIVKIYEGTGTSVLV 174 Query: 364 DGGIQNVGHIAKALALGASTVMMGS 388 GI+ + +++ LGA +++ S Sbjct: 175 GAGIKTGEDVRRSIGLGARGILVAS 199 >1N7K-A nrPDB Length = 234 Score = 32.7 bits (73), Expect = 0.40, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 30/69 (43%), Gaps = 10/69 (14%) Query: 316 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 375 AG D ++ G V G T V++++ A+ G+ V A GGI++ Sbjct: 160 AGADIVKTSTG---------VYTKGGDPVT-VFRLASLAKPLGMGVKASGGIRSGIDAVL 209 Query: 376 ALALGASTV 384 A+ GA + Sbjct: 210 AVGAGADII 218 >4IQL-A nrPDB Length = 333 Score = 32.7 bits (73), Expect = 0.43, Method: Composition-based stats. Identities = 39/132 (29%), Positives = 62/132 (46%), Gaps = 10/132 (7%) Query: 304 VVTAAQAKNLIDAGVDALRV-GMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVI 362 V +A A+ AGVDA+ G +G GR + T + + E +PV+ Sbjct: 136 VSSATFARKSEAAGVDAIVAEGFEAGGHN--------GREETTTLCLIPEVVDAVNIPVV 187 Query: 363 ADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPG-EYFFSDGIRLKKYRGMGSLDAMD 421 A GGI + +A ALALGA V +G+ A + E+ E F + R + M SL A+ Sbjct: 188 AAGGIASGRAVAAALALGADAVQVGTRFALSEESSAHEDFKAHCRRSVEGDTMLSLKAVS 247 Query: 422 KHLSSQNRYFSE 433 +N+++ + Sbjct: 248 PTRLLKNKFYQD 259 Score = 29.7 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 17/104 (16%), Positives = 45/104 (43%), Gaps = 9/104 (8%) Query: 54 ALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFI-HHNCTPEFQANEVRKVKKY-- 110 + + + ++ P++S M + +A A++ GG+G I + P+ + +R K Sbjct: 23 RICELLGIEHPIISGGMVWCSGWKLASAVSNCGGLGLIGAGSMHPDNLEHHIRSCKAATD 82 Query: 111 EQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRL 154 + + P++ D++ ++ H +P+ T ++ Sbjct: 83 KPFGVNVPLLYPEMDKIMEI--IMREH----VPVVVTSAGSPKV 120 >6DU6-A nrPDB Length = 565 Score = 32.4 bits (72), Expect = 0.46, Method: Composition-based stats. Identities = 40/176 (22%), Positives = 59/176 (33%), Gaps = 29/176 (16%) Query: 252 THEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNL---QVIGGNVVTAA 308 E DK L + GVDV+ + I +K I+ I + Sbjct: 237 VSEKDKSDLQFGVEQGVDVIF-----ASFIRNAAALKEIRTILGEKGKNIKIISKIENQQ 291 Query: 309 QAKNL--IDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIA--- 363 +NL I A D + V G I I E + Q + + + R G PVI Sbjct: 292 GMQNLDAIIAASDGIMVARGDLGIEIPAEKVFLA--QKSMIARC----NRAGKPVICATQ 345 Query: 364 --DGGIQNVG-------HIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKK 410 + I+ +A A+ GA VM+ A E P E + K+ Sbjct: 346 MLESMIKKPRPTRAEISDVANAIIDGADCVMLSGETAKG-EYPLECVLTMAKTCKE 400 >6CTY-A nrPDB Length = 372 Score = 32.4 bits (72), Expect = 0.47, Method: Composition-based stats. Identities = 23/140 (16%), Positives = 47/140 (33%), Gaps = 22/140 (15%) Query: 260 LDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVD 319 + LL V +D + F +++ I+ K+P L+++ ++ T A + AG Sbjct: 159 MPLLIHGEVTDAAVDIFDREARFIDQILEPIRQKFPELKIVFEHITTKDAADY-VLAGNR 217 Query: 320 ALRVGMGSGSICITQEVLACG--RPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKAL 377 L + + + + G RP + + + + A+ Sbjct: 218 FLGATVTPQHLMFNRNHMLVGGIRPHLFCLPILKRSTHQQA--------------LRAAV 263 Query: 378 ALGASTVMMGSLLAATTEAP 397 A G+ T AP Sbjct: 264 ASGSD-----RFFLGTDSAP 278 >1QAP-A nrPDB Length = 296 Score = 32.4 bits (72), Expect = 0.49, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 36/77 (46%), Gaps = 9/77 (11%) Query: 250 IGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKY-IKDKYPNLQV-IGGNVVTA 307 + ++ LD +AG D+++LD F + ++ +K ++ + GNV TA Sbjct: 211 VEVEVENLDELDDALKAGADIIMLD------NFNTDQMREAVKRVNGQARLEVSGNV-TA 263 Query: 308 AQAKNLIDAGVDALRVG 324 + + GVD + VG Sbjct: 264 ETLREFAETGVDFISVG 280 >5DO8-B nrPDB Length = 555 Score = 32.0 bits (71), Expect = 0.71, Method: Composition-based stats. Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 9/71 (12%) Query: 231 RDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVV----VLDSSQGNSIFQINM 286 + YP + D+ G +G + +LD L + GVDV+ V DS Q ++ + I Sbjct: 14 QIYPKSFNDSN-----GDGVGDIQGIIEKLDYLKELGVDVIWLSPVYDSPQDDNGYDIRD 68 Query: 287 IKYIKDKYPNL 297 + I ++Y ++ Sbjct: 69 YQKIYEEYGDM 79 >4UTT-A nrPDB Length = 229 Score = 32.0 bits (71), Expect = 0.72, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 21/39 (53%) Query: 352 EYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLL 390 E + +PVI +G I + KAL LGA + ++G + Sbjct: 177 ELVKTVKIPVICEGRINTPEELKKALDLGAYSAVVGGAI 215 >6NKE-A nrPDB Length = 252 Score = 32.0 bits (71), Expect = 0.74, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 24/53 (45%) Query: 337 LACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSL 389 G P+ + +S + +P+I GGI++ + GA ++ GS+ Sbjct: 173 AGSGAPRPVSEDTISYVKSKINIPLIVGGGIRDPETAMRIALAGADMIVTGSI 225 Score = 29.3 bits (64), Expect = 4.5, Method: Composition-based stats. Identities = 11/40 (27%), Positives = 18/40 (45%) Query: 285 NMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVG 324 + I Y+K K ++GG + A + AG D + G Sbjct: 184 DTISYVKSKINIPLIVGGGIRDPETAMRIALAGADMIVTG 223 >1IBJ-A nrPDB Length = 464 Score = 31.6 bits (70), Expect = 0.95, Method: Composition-based stats. Identities = 32/148 (21%), Positives = 55/148 (37%), Gaps = 18/148 (12%) Query: 263 LAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALR 322 L + G ++V D G S + + P V+ V T +D + Sbjct: 167 LIKNGEEIVAGDDVYGGSD------RLLSQVVPRSGVVVKRVNTTK---------LDEVA 211 Query: 323 VGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGAS 382 +G + + E R Q + + K+SE A G V+ D I + +++ L LGA Sbjct: 212 AAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPV-LSRPLELGAD 270 Query: 383 TVM--MGSLLAATTEAPGEYFFSDGIRL 408 VM +A ++ G +L Sbjct: 271 IVMHSATKFIAGHSDVMAGVLAVKGEKL 298 >2A1T-A nrPDB Length = 421 Score = 31.2 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 15/62 (24%), Positives = 23/62 (37%), Gaps = 2/62 (3%) Query: 369 NVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQN 428 G IA LA A ++ G+ TE P E D + Y G + + + Sbjct: 360 FAGDIANQLATDAVQILGGNGF--NTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHID 417 Query: 429 RY 430 +Y Sbjct: 418 KY 419 >3OIX-A nrPDB Length = 345 Score = 31.2 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 30/68 (44%), Gaps = 5/68 (7%) Query: 345 TAVYKVSEYARRFG--VPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFF 402 TA+ V + +R + +I GG++ + + GAS V +G+ L E P + F Sbjct: 260 TALANVHAFYKRLNPSIQIIGTGGVKTGRDAFEHILCGASMVQIGTAL--HQEGP-QIFK 316 Query: 403 SDGIRLKK 410 LK Sbjct: 317 RITKELKA 324 >4AXK-A nrPDB Length = 250 Score = 31.2 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 27/57 (47%) Query: 351 SEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIR 407 +E R+ + V GGI++ + +ALA GA+ V +G+ E + G + Sbjct: 67 AEITRQLDIKVELTGGIRDDASLERALATGATRVNIGTAALEKPEWIADVIRRHGEK 123 Score = 28.1 bits (61), Expect = 8.8, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 25/66 (37%), Gaps = 6/66 (9%) Query: 331 CITQEVLAC---GRPQATAVYKVSEYARRFGVPVIADGGIQNVGHI---AKALALGASTV 384 C V G V + + A P++A GGI + + AK G +V Sbjct: 163 CSRFVVTDVSKDGTLTGPNVDLLRDVAAATDAPIVASGGISTLEDVLGLAKYQDEGIDSV 222 Query: 385 MMGSLL 390 ++G L Sbjct: 223 IIGKAL 228 >2ISS-A nrPDB Length = 313 Score = 30.8 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 22/45 (48%), Gaps = 2/45 (4%) Query: 284 INMIKYIKD--KYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMG 326 + +++ +K + P + G V T A A ++ G D + VG G Sbjct: 214 VELLREVKRLGRLPVVNFAAGGVATPADAALMMMLGADGVFVGSG 258 Score = 30.4 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 2/57 (3%) Query: 334 QEVLACGRPQATAVYKVSEYARRFGVPVI--ADGGIQNVGHIAKALALGASTVMMGS 388 +E++A G+ V + E R +PV+ A GG+ A + LGA V +GS Sbjct: 201 EELVAYGKEIGAPVELLREVKRLGRLPVVNFAAGGVATPADAALMMMLGADGVFVGS 257 >2B7N-A nrPDB Length = 273 Score = 30.8 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 22/104 (21%), Positives = 39/104 (37%), Gaps = 2/104 (1%) Query: 221 IIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNS 280 ++ T L+ +D A+K L A I + AG D+V+ D+ Sbjct: 156 MLKDTHLRHVKDLKSFLTHARKNLPFTAKIEIECESFEEAKNAMNAGADIVMCDNLSVLE 215 Query: 281 IFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVG 324 +I + YP + + ++ +GVDA+ VG Sbjct: 216 TKEIAAYRD--AHYPFVLLEASGNISLESINAYAKSGVDAISVG 257 >3M6M-D nrPDB Length = 143 Score = 30.8 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 40/95 (42%), Gaps = 10/95 (10%) Query: 234 PLASKDAKKQLL--CGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIK 291 A++ ++LL G + + LD +A+ D V++D + ++M+K ++ Sbjct: 23 HEANRMVLQRLLEKAGHKVLCVNGAEQVLDAMAEEDYDAVIVDL-HMPGMNGLDMLKQLR 81 Query: 292 ------DKYPNLQVIGGNVVTAAQAKNLIDAGVDA 320 +Y + V+ +V T + AG A Sbjct: 82 VMQASGMRYTPVVVLSADV-TPEAIRACEQAGARA 115 >3ZUY-A nrPDB Length = 323 Score = 30.8 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 28/109 (25%), Positives = 46/109 (42%), Gaps = 7/109 (6%) Query: 172 DCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNR 231 + ++T L++A + ++ A ++ K LPIV +V + + +K Sbjct: 135 STLISPLLTPAIFLMLAGEMLEIQAAGMLMSIVKMVLLPIV--LGLIVHKVLGSKTEKLT 192 Query: 232 D-YPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGN 279 D PL S A L+ GA +G + LL A VVVL + G Sbjct: 193 DALPLVSVAAIV-LIIGAVVGASKGKIMESGLLIFA---VVVLHNGIGY 237 >4HDR-A nrPDB Length = 348 Score = 30.4 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 33/80 (41%) Query: 267 GVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMG 326 G D+VV+D + + + + K Y G +T QA ++ G+D + + Sbjct: 109 GADMVVVDMGVAGDLSYVPGLWHRKIAYGTQDFTEGPAMTREQAIQAVETGIDIVNDRVK 168 Query: 327 SGSICITQEVLACGRPQATA 346 G+ C + G ++A Sbjct: 169 HGNRCFCLGEMGIGNTTSSA 188 >4KCV-B nrPDB Length = 499 Score = 30.4 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 38/225 (16%), Positives = 73/225 (32%), Gaps = 35/225 (15%) Query: 205 KKGKLPIVNEDDELVAIIARTD---LKKNRDYPLASKDAKKQLLCGAAI---GTHEDDKY 258 + G V++ + ++++ D LK + + D + L G + E D+ Sbjct: 137 RPGGSIYVDDGVMTLRVVSKEDDRTLKCHVNNHHRLTDRRGINLPGCEVDLPAVSEKDRK 196 Query: 259 RLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNL---QVIGGNVVTAAQAKNL-- 313 L+ GVD++ + I ++ ++ +I + +N+ Sbjct: 197 DLEFGVAQGVDMIF-----ASFIRTAEQVREVRAALGEKGKDILIISKIENHQGVQNIDS 251 Query: 314 IDAGVDALRVGMGS------------GSICITQEVLACGRPQATAVYKVSEYARRFGVPV 361 I + + V G +CI + G+P A + E P Sbjct: 252 IIEASNGIMVARGDLGVEIPAEKVCVAQMCIISKCNVVGKPVICATQML-ESMTSNPRPT 310 Query: 362 IADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGI 406 A+ V +A A+ GA VM+ A P E Sbjct: 311 RAE-----VSDVANAVLNGADCVMLSGETAKGK-YPNEVVQYMAR 349 >4MWA-D nrPDB Length = 276 Score = 30.4 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 33/84 (39%), Gaps = 19/84 (22%) Query: 305 VTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIAD 364 T A+ K L +AG +RV P A +++ ++ +P++AD Sbjct: 44 ATVAEIKRLEEAGCQVVRV----------------AVPDERAANAIADIKKQINIPLVAD 87 Query: 365 GGIQNVGHIA-KALALGASTVMMG 387 I +A KA+ G V + Sbjct: 88 --IHFDYRLALKAIEGGIDKVRIN 109 >4KRZ-A nrPDB Length = 519 Score = 30.4 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 36/225 (16%), Positives = 72/225 (32%), Gaps = 35/225 (15%) Query: 205 KKGKLPIVNEDDELVAIIARTDLKKNRDYPLAS---KDAKKQLLCGAAI---GTHEDDKY 258 + G +++ + ++++ D + Y + D K L G + E D+ Sbjct: 157 RPGGFIYIDDGVLSLKVLSKEDEYTLKCYVNNAHFLTDRKGCNLPGCEVDLPAVSEKDRE 216 Query: 259 RLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNL---QVIGGNVVTAAQAKNL-- 313 L + G+D+V + I ++ +++ +I + +N+ Sbjct: 217 DLKFGVEQGIDMVF-----ASFIRTAEQVQEVREALGEKGKDILIISKIENHQGVQNIDG 271 Query: 314 IDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNV--- 370 I D + V G + I E + + + V+ G PVI + Sbjct: 272 IIEASDGIMVARGDLGVEIPAEKVVVAQMILISKCNVA------GKPVICATQMLESMTT 325 Query: 371 ---------GHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGI 406 +A A+ GA VM+ A P E Sbjct: 326 NPRPTRAEVSDVANAVFNGADCVMLSGETAKGK-YPNEVVQYMAR 369 >4ADT-A nrPDB Length = 297 Score = 30.4 bits (67), Expect = 2.0, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 16/35 (45%) Query: 292 DKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMG 326 + P + G + T A A + G+D + VG G Sbjct: 206 KRLPVVNFAAGGIATPADAAMCMQLGMDGVFVGSG 240 >1TQJ-A nrPDB Length = 230 Score = 30.4 bits (67), Expect = 2.0, Method: Composition-based stats. Identities = 23/134 (17%), Positives = 48/134 (35%), Gaps = 12/134 (8%) Query: 260 LDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVD 319 ++ A+AG D++ + S + I++ N T + D Sbjct: 78 VEDFAKAGADIISVHVEHNASPHLHRTLCQIRE-LGKKAGAVLNPSTPLDFLEYVLPVCD 136 Query: 320 -ALRVGMGSGSICITQEVLACGRPQATA-VYKVSEYARRFGV-PVI-ADGGIQNVGHIAK 375 L + + G + P+ + + + G+ P I DGG++ + + Sbjct: 137 LILIMSVNPGFGGQSFI------PEVLPKIRALRQMCDERGLDPWIEVDGGLK-PNNTWQ 189 Query: 376 ALALGASTVMMGSL 389 L GA+ ++ GS Sbjct: 190 VLEAGANAIVAGSA 203 >2CTZ-A nrPDB Length = 421 Score = 30.4 bits (67), Expect = 2.1, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 25/51 (49%), Gaps = 2/51 (3%) Query: 336 VLACGRPQATA--VYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTV 384 V + G P + +++ AR GV +I D G++ + LA GA+ V Sbjct: 150 VESIGNPALNIPDLEALAQAAREKGVALIVDNTFGMGGYLLRPLAWGAALV 200 >4IP7-A nrPDB Length = 543 Score = 30.4 bits (67), Expect = 2.1, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 35/81 (43%), Gaps = 3/81 (3%) Query: 248 AAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTA 307 A IG RL + +AG+++ L+ S G+ + I +++ ++ G+ ++ Sbjct: 61 ATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREA---VESFAGSPLSY 117 Query: 308 AQAKNLIDAGVDALRVGMGSG 328 +D +R G+ G Sbjct: 118 RPVAIALDTKGPEIRTGILQG 138 >5LNS-A nrPDB Length = 316 Score = 30.4 bits (67), Expect = 2.1, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 17/34 (50%) Query: 293 KYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMG 326 + P +Q G V T A A ++ G D + VG G Sbjct: 220 RLPVVQFAAGGVATPADAALMMQLGCDGVFVGSG 253 >2NV2-A nrPDB Length = 294 Score = 30.0 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 16/34 (47%) Query: 293 KYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMG 326 K P + G V T A A ++ G D + VG G Sbjct: 204 KLPVVNFAAGGVATPADAALMMQLGADGVFVGSG 237 >1MZH-A nrPDB Length = 225 Score = 30.0 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 19/112 (16%), Positives = 42/112 (37%), Gaps = 22/112 (19%) Query: 282 FQINMIKYIKDKYP---NLQVIGGNVVTAA----QAKNLIDAGVDALRVGMGSGSICITQ 334 F + +K I + P + ++ + + I+AG D ++ G Sbjct: 103 FVVEELKEIFRETPSAVHKVIVETPYLNEEEIKKAVEICIEAGADFIKTSTG-------- 154 Query: 335 EVLACGRPQATAVYKVS--EYARRFGVPVIADGGIQNVGHIAKALALGASTV 384 P+ T + +V + + + + V A GGI+++ + GA + Sbjct: 155 -----FAPRGTTLEEVRLIKSSAKGRIKVKASGGIRDLETAISMIEAGADRI 201 Score = 29.7 bits (65), Expect = 3.6, Method: Composition-based stats. Identities = 25/142 (17%), Positives = 56/142 (39%), Gaps = 5/142 (3%) Query: 189 PAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGA 248 + +KEA E ++ + L IV + +++ ++ + A +++ Sbjct: 68 KTSVKVKEAVEAVRDGAQE-LDIVWNLSAFKSEKYDFVVEELKEIFRETPSAVHKVIVET 126 Query: 249 AIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIG--GNVVT 306 E+ K +++ +AG D + + + ++ IK + G + Sbjct: 127 PYLNEEEIKKAVEICIEAGADFIKTSTGFAPRGTTLEEVRLIKSSAKGRIKVKASGGIRD 186 Query: 307 AAQAKNLIDAGVDALRVGMGSG 328 A ++I+AG D R+G SG Sbjct: 187 LETAISMIEAGAD--RIGTSSG 206 >5LNT-A nrPDB Length = 316 Score = 30.0 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 17/34 (50%) Query: 293 KYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMG 326 + P +Q G V T A A ++ G D + VG G Sbjct: 221 RLPVVQFAAGGVATPADAALMMQLGCDGVFVGSG 254 >3Q58-A nrPDB Length = 229 Score = 30.0 bits (66), Expect = 2.7, Method: Composition-based stats. Identities = 33/153 (21%), Positives = 60/153 (39%), Gaps = 12/153 (7%) Query: 242 KQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIG 301 K+ L G+ + +D LAQAG D++ D+S + I+ + + + L + Sbjct: 77 KRDLTGSPVRITP-YLQDVDALAQAGADIIAFDASFRSRPVDIDSL-LTRIRLHGLLAMA 134 Query: 302 GNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPV 361 + T + + G++ + + + IT P V ++S G V Sbjct: 135 -DCSTVNEGISCHQKGIEFIGTTLSGYTGPITPVE-----PDLAMVTQLSHA----GCRV 184 Query: 362 IADGGIQNVGHIAKALALGASTVMMGSLLAATT 394 IA+G A A+ GA V +GS + Sbjct: 185 IAEGRYNTPALAANAIEHGAWAVTVGSAITRIE 217 >1EYE-A nrPDB Length = 280 Score = 30.0 bits (66), Expect = 2.7, Method: Composition-based stats. Identities = 24/116 (20%), Positives = 43/116 (37%), Gaps = 15/116 (12%) Query: 276 SQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQE 335 ++ + + + + + P++ V GNVV A +L+ + DA+ G+ + Sbjct: 121 AEADVPWVLMHWRAVSADTPHVPVRYGNVV-AEVRADLLASVADAVAAGVDP-----ARL 174 Query: 336 VLACGRPQAT------AVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVM 385 VL G A A+ G+PV+ + AL G VM Sbjct: 175 VLDPGLGFAKTAQHNWAILHALPELVATGIPVLVGASRKR---FLGALLAGPDGVM 227 >2P8U-A nrPDB Length = 478 Score = 29.7 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 38/103 (36%), Gaps = 10/103 (9%) Query: 235 LASKDAKKQLLCGAA--IGTHEDDKYRLDLLAQAG--VDVVVLDSSQ---GNSIFQINMI 287 S D +L G I + K L L + D+ +D++ G + N + Sbjct: 89 NLSYDCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAV 148 Query: 288 KYIKDKYPN---LQVIGGNVVTAAQAKNLIDAGVDALRVGMGS 327 +I+ + V+ G++ A GV A+ + +G Sbjct: 149 NWIESSSWDGRYALVVAGDIAVYATGNARPTGGVGAVALLIGP 191 >6HYE-A nrPDB Length = 314 Score = 29.7 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 16/49 (32%), Positives = 24/49 (48%), Gaps = 3/49 (6%) Query: 343 QATAVYKVSEYARRFG-VPVI--ADGGIQNVGHIAKALALGASTVMMGS 388 + +A Y + ++ G VPV+ A GGI A + LG V +GS Sbjct: 209 KISAPYDLVAQTKQMGRVPVVQFASGGITTPADAALMMQLGCDGVFVGS 257 >5VIS-A nrPDB Length = 275 Score = 29.7 bits (65), Expect = 3.1, Method: Composition-based stats. Identities = 26/88 (29%), Positives = 35/88 (39%), Gaps = 15/88 (17%) Query: 310 AKNLIDAGVDALRVG---MGSGSICIT-QEVLACGRPQATAVYKVSEYARRFGVPVIADG 365 A+ L+ G D + +G G GS IT E LA P A+ A + D Sbjct: 36 ARELLSQGADIIEIGGESTGPGSNTITADEELARIVPVIRAIRSSLPDAN-----IAVD- 89 Query: 366 GIQNVGHIA-KALALGASTVMMGSLLAA 392 +A KAL LGA M+ + A Sbjct: 90 --TYKAEVARKALELGA--TMINDVSAG 113 >4NU7-A nrPDB Length = 246 Score = 29.7 bits (65), Expect = 3.5, Method: Composition-based stats. Identities = 15/87 (17%), Positives = 34/87 (39%), Gaps = 6/87 (6%) Query: 244 LLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQ---GNSIFQINMIKYIK---DKYPNL 297 + G AI + + LA D++++ + + G F +M++ ++ +P L Sbjct: 118 IKAGLAIKPATKFEDLGEALAGDNFDMLLVMTVEPGFGGQKFMADMLQKVRTARSLFPKL 177 Query: 298 QVIGGNVVTAAQAKNLIDAGVDALRVG 324 + + K AG + + G Sbjct: 178 NIQVDGGLDGETVKPAASAGANVIVAG 204 >3NWR-A nrPDB Length = 432 Score = 29.7 bits (65), Expect = 3.5, Method: Composition-based stats. Identities = 26/117 (22%), Positives = 42/117 (35%), Gaps = 14/117 (11%) Query: 279 NSIFQINMIKYIKDKYPNLQVIGGNVV-----TAAQAKNLIDAGVDALRVGMGSGSICIT 333 + + + +KD+ +I NV TAA + L +AGVD ++ +C Sbjct: 147 HGVAGTRALTDVKDRPMIGTIIKPNVGLSAAETAALVRELCEAGVDFIK----DDEVCAN 202 Query: 334 QEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALA-----LGASTVM 385 + +V Y R G PV+ I + + A G S VM Sbjct: 203 PAHAPLAERVRAVMSEVRRYRERSGRPVMVAFNITDDLDAMRRHAELVEREGGSCVM 259 >2VEP-A nrPDB Length = 244 Score = 29.7 bits (65), Expect = 3.5, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 28/58 (48%) Query: 350 VSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIR 407 ++E A+ + V GGI++ +A ALA G + V +G+ T E + G + Sbjct: 67 IAEVAQAMDIKVELSGGIRDDDTLAAALATGCTRVNLGTAALETPEWVAKVIAEHGDK 124 >1VR9-A nrPDB Length = 213 Score = 29.3 bits (64), Expect = 4.2, Method: Composition-based stats. Identities = 17/125 (13%), Positives = 43/125 (34%), Gaps = 11/125 (8%) Query: 106 KVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDF 165 KVKK+ D ++ VR+ ++ + D G++ +++ Sbjct: 14 KVKKW---VTQDFPMVEESATVRECLHRMRQYQTNECIVKDRE---GHFRGVV-NKEDLL 66 Query: 166 LKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIART 225 + + F + + + A + ++ LP+V+E+ L ++ Sbjct: 67 DLDLDSSVFNKVSLPDFF----VHEEDNITHALLLFLEHQEPYLPVVDEEMRLKGAVSLH 122 Query: 226 DLKKN 230 D + Sbjct: 123 DFLEA 127 >1TJR-A nrPDB Length = 261 Score = 29.3 bits (64), Expect = 4.4, Method: Composition-based stats. Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 14/88 (15%) Query: 336 VLACGRPQATAVYKVSEYARR----FGVPVIADGGIQNVGHIAKALALGASTVMMGSLL- 390 V P+A +V + PV GI H+ + GA V++GS + Sbjct: 174 VNGVTGPRANVNPRVESLIQEVKKVTNKPVAVGFGISKPEHVKQIAQWGADGVIIGSAMV 233 Query: 391 --AATTEAPGEYFFSDG-IRLKKY-RGM 414 +P G RL++Y RGM Sbjct: 234 RQLGEAASP-----KQGLRRLEEYARGM 256 >5G1T-A nrPDB Length = 256 Score = 29.3 bits (64), Expect = 4.5, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 20/52 (38%) Query: 337 LACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGS 388 P + + VPV GG++ +A L G + V++GS Sbjct: 55 TGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRTEEDVAALLKAGVARVVIGS 106 >4WY0-A nrPDB Length = 305 Score = 29.3 bits (64), Expect = 4.7, Method: Composition-based stats. Identities = 21/89 (23%), Positives = 35/89 (39%), Gaps = 9/89 (10%) Query: 302 GNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPV 361 GN+V +++ +V E++A + V + E R +PV Sbjct: 165 GNIV--EAVRHMRKVNAQIRKVVN-----MSEDELVAEAKQLGAPVEVLREIKRLGRLPV 217 Query: 362 I--ADGGIQNVGHIAKALALGASTVMMGS 388 + A GG+ A + LGA V +GS Sbjct: 218 VNFAAGGVTTPADAALMMHLGADGVFVGS 246 >2W6R-A nrPDB Length = 266 Score = 28.9 bits (63), Expect = 5.0, Method: Composition-based stats. Identities = 19/83 (22%), Positives = 29/83 (34%), Gaps = 16/83 (19%) Query: 357 FGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGS 416 +P+IA GG + H +A GA + S+ + D LK+Y Sbjct: 73 TTLPIIASGGAGKMEHFLEAFLAGADKALAASVF--------HFREIDMRELKEY----- 119 Query: 417 LDAMDKHLSSQNRYFSEADKIKV 439 + KH S D +V Sbjct: 120 ---LKKHGGSGQAVVVAIDAKRV 139 >3OA3-A nrPDB Length = 288 Score = 28.9 bits (63), Expect = 5.3, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 32/88 (36%), Gaps = 21/88 (23%) Query: 298 QVIGGNVVTAAQAKNLIDAGVDALRVG---MGSGSICITQEVLACGRPQATAVYKVSEYA 354 ++I G V+++ AG D ++ G G+ +AV + Sbjct: 189 EIIAGCVLSS-------LAGADYVKTSTGFNGPGASIEN-------VSLMSAVCDSLQSE 234 Query: 355 RRFGVPVIADGGIQNVGHIAKALALGAS 382 R V A GGI+ + K + GA Sbjct: 235 TR----VKASGGIRTIEDCVKMVRAGAE 258 >3OVQ-A nrPDB Length = 228 Score = 28.9 bits (63), Expect = 5.4, Method: Composition-based stats. Identities = 6/39 (15%), Positives = 17/39 (43%) Query: 286 MIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVG 324 + +++ ++P+L + V +AG + + G Sbjct: 159 KVHWLRTQFPSLDIEVDGGVGPDTVHKCAEAGANMIVSG 197 >6OMZ-A nrPDB Length = 293 Score = 28.9 bits (63), Expect = 5.5, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 34/92 (36%), Gaps = 10/92 (10%) Query: 308 AQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGI 367 L+ AG + VG S T+ + T V + E A + G+ + D Sbjct: 49 EHGLALVAAGAQIIDVGGESTRPGATRIDPGVEAARVTPV--IRELAAQ-GITISID--- 102 Query: 368 QNVGHIAK-ALALGASTVMMGSLLAATTEAPG 398 +A+ AL GA V + ++ PG Sbjct: 103 TMHADVARAALEAGAHIV---NDVSGGRADPG 131 >3MDE-A nrPDB Length = 385 Score = 28.9 bits (63), Expect = 6.2, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 20/62 (32%), Gaps = 2/62 (3%) Query: 369 NVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQN 428 IA LA A V G+ TE P E D + Y G + + Sbjct: 325 YAADIANQLATDAVQVFGGNGF--NTEYPVEKLMRDAKIYQIYEGTAQIQRIIIAREHIG 382 Query: 429 RY 430 RY Sbjct: 383 RY 384 >3DM5-A nrPDB Length = 443 Score = 28.5 bits (62), Expect = 7.0, Method: Composition-based stats. Identities = 58/312 (18%), Positives = 104/312 (33%), Gaps = 36/312 (11%) Query: 152 SRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKG-KLP 210 ++ I+ FL E ++E T + + +G T A K+G K+ Sbjct: 73 EHIIKIVYEELTKFLGTEAKPIEIKEKPTILLMVGIQGSGKTTTVAKLARYFQKRGYKVG 132 Query: 211 IVNED----DELVAIIARTDLKKNRDYPL-ASKDAKKQLLCGAAIGTHEDDKYRLDLLAQ 265 +V D + D + KDA K K +D Sbjct: 133 VVCSDTWRPGAYHQLRQLLDRYHIEVFGNPQEKDAIK------------LAKEGVDYFKS 180 Query: 266 AGVDVVVLDSS--QGNSIFQINMIKYIKDKY-PN--LQVIGGNVVTAAQAKNLIDAGVDA 320 GVD++++D++ I +K I + P+ + VI G + A + L Sbjct: 181 KGVDIIIVDTAGRHKEDKALIEEMKQISNVIHPHEVILVIDGTIGQQAYNQALAFKEATP 240 Query: 321 LRVGMGSGSICITQE-VLACGRPQATAVYKVSEYARRFGVPVIADG--GIQNVGHIAKAL 377 + GSI +T+ A G +AV + G D +++ L Sbjct: 241 I------GSIIVTKLDGSAKGGGALSAVAATGAPIKFIGTGEKIDDIEPFDPPRFVSRLL 294 Query: 378 ALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKI 437 LG + LL E E + + RG +L M L + + + Sbjct: 295 GLGD----IQGLLEKFKELEKEVEIKEEDIERFLRGKFTLKDMYAQLEAMRKMGPLKQIL 350 Query: 438 KVAQGVSGAVQD 449 ++ G+ ++ D Sbjct: 351 RMIPGLGYSLPD 362 >1A3W-A nrPDB Length = 500 Score = 28.5 bits (62), Expect = 7.4, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 25/53 (47%), Gaps = 3/53 (5%) Query: 250 IGTHEDDKYRLDLLAQAGVDVVVLDSSQG---NSIFQINMIKYIKDKYPNLQV 299 IG ++ L L +AG+++V ++ S G I+ + ++ YP + Sbjct: 27 IGPKTNNPETLVALRKAGLNIVRMNFSHGSYEYHKSVIDNARKSEELYPGRPL 79 >4FIQ-A nrPDB Length = 335 Score = 28.1 bits (61), Expect = 8.5, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 17/34 (50%) Query: 293 KYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMG 326 + P + G V T A A ++ G+D + VG G Sbjct: 247 RLPVVNFAAGGVATPADAALMMAMGMDGVFVGSG 280 >2YZR-A nrPDB Length = 330 Score = 28.1 bits (61), Expect = 8.7, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 16/34 (47%) Query: 293 KYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMG 326 + P + G V T A A ++ G D + VG G Sbjct: 240 RLPVVNFAAGGVATPADAALMMQLGSDGVFVGSG 273 >4J9J-A nrPDB Length = 246 Score = 28.1 bits (61), Expect = 9.2, Method: Composition-based stats. Identities = 23/130 (17%), Positives = 45/130 (34%), Gaps = 16/130 (12%) Query: 266 AGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGM 325 AG D V ++++ ++ ++I I + + V+ V + ++ G+ Sbjct: 121 AGADKVSINTA---AVENPSLITQIAQTFGSQAVVVAIVAKRVDGEFMVFTYSGKKNTGI 177 Query: 326 ------------GSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHI 373 G+G I +T G + +P+IA GG + H Sbjct: 178 LLRDWVVEVEKRGAGEILLTSIDR-VGTKSGYDTEMIRFVRPLTTLPIIASGGAGKMEHF 236 Query: 374 AKALALGAST 383 +A GA Sbjct: 237 LEAFLAGADA 246 >2B2H-A nrPDB Length = 399 Score = 28.1 bits (61), Expect = 9.2, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 32/65 (49%), Gaps = 4/65 (6%) Query: 270 VVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQ---AKNLIDAGVDALRVGMG 326 VVV ++S + F +I +IK K +L ++ G + A A +D + +G+ Sbjct: 220 VVVTNTSAAVAGFVWMVIGWIKGKPGSLGIVSGAIAGLAAITPAAGFVDVKGAIV-IGLV 278 Query: 327 SGSIC 331 +G +C Sbjct: 279 AGIVC 283 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.133 0.338 Lambda K H 0.267 0.0406 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,215,262 Number of Sequences: 36641 Number of extensions: 703256 Number of successful extensions: 3002 Number of sequences better than 10.0: 149 Number of HSP's better than 10.0 without gapping: 159 Number of HSP's successfully gapped in prelim test: 74 Number of HSP's that attempted gapping in prelim test: 2592 Number of HSP's gapped (non-prelim): 323 length of query: 514 length of database: 10,336,785 effective HSP length: 101 effective length of query: 413 effective length of database: 6,636,044 effective search space: 2740686172 effective search space used: 2740686172 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 61 (28.1 bits)