BLASTP 2.2.23 [Feb-03-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= P12081
(509 letters)
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
36,641 sequences; 10,336,785 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
4X5O-A nrPDB 1025 0.0
5W6M-A nrPDB 911 0.0
3NET-A nrPDB 222 2e-58
2LW7-A nrPDB 209 2e-54
6NHI-A nrPDB 209 3e-54
4YRG-A nrPDB 158 4e-39
3HRI-A nrPDB 155 5e-38
1WU7-A nrPDB 125 5e-29
1X59-A nrPDB 114 8e-26
5E3I-A nrPDB 93 3e-19
1ADJ-A nrPDB 89 3e-18
1QE0-A nrPDB 88 9e-18
3RAC-A nrPDB 87 2e-17
2EL9-A nrPDB 86 3e-17
3OD1-A nrPDB 80 2e-15
4E51-A nrPDB 76 4e-14
1Z7M-A nrPDB 49 6e-06
6FUA-A nrPDB 39 0.005
1F8S-A nrPDB 36 0.046
3KVE-A nrPDB 35 0.064
2DJV-A nrPDB 33 0.25
1REO-A nrPDB 32 0.88
5XIL-A nrPDB 30 2.5
5Z50-A nrPDB 30 2.9
1SGM-A nrPDB 29 4.8
5Z5E-A nrPDB 29 5.9
3A31-A nrPDB 28 6.9
>4X5O-A nrPDB
Length = 509
Score = 1025 bits (2651), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 509/509 (100%), Positives = 509/509 (100%)
Query: 1 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK 60
MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK
Sbjct: 1 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK 60
Query: 61 GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQ 120
GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQ
Sbjct: 61 GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQ 120
Query: 121 GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAG 180
GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAG
Sbjct: 121 GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAG 180
Query: 181 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK 240
NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK
Sbjct: 181 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK 240
Query: 241 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG 300
LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG
Sbjct: 241 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG 300
Query: 301 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG 360
DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG
Sbjct: 301 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG 360
Query: 361 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL 420
GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL
Sbjct: 361 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL 420
Query: 421 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS 480
LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS
Sbjct: 421 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS 480
Query: 481 VTSREEVDVRREDLVEEIKRRTGQPLCIC 509
VTSREEVDVRREDLVEEIKRRTGQPLCIC
Sbjct: 481 VTSREEVDVRREDLVEEIKRRTGQPLCIC 509
>5W6M-A nrPDB
Length = 450
Score = 911 bits (2354), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 449/450 (99%), Positives = 450/450 (100%)
Query: 54 FVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKL 113
FVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKL
Sbjct: 1 FVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKL 60
Query: 114 IYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQ 173
IYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQ
Sbjct: 61 IYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQ 120
Query: 174 CDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRT 233
C+FDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRT
Sbjct: 121 CEFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRT 180
Query: 234 ICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNK 293
ICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNK
Sbjct: 181 ICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNK 240
Query: 294 QALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLG 353
QALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLG
Sbjct: 241 QALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLG 300
Query: 354 VGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLV 413
VGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLV
Sbjct: 301 VGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLV 360
Query: 414 ASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKD 473
ASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKD
Sbjct: 361 ASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKD 420
Query: 474 GVIKLRSVTSREEVDVRREDLVEEIKRRTG 503
GVIKLRSVTSREEVDVRREDLVEEIKRRTG
Sbjct: 421 GVIKLRSVTSREEVDVRREDLVEEIKRRTG 450
>3NET-A nrPDB
Length = 465
Score = 222 bits (566), Expect = 2e-58, Method: Compositional matrix adjust.
Identities = 158/473 (33%), Positives = 249/473 (52%), Gaps = 42/473 (8%)
Query: 53 KFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSK 112
K TP G ++ P + + + D I R ++ +G I+TP E E L K +
Sbjct: 9 KINFSTPSGFPEFLPSEKRLELYLLDTIRRVYESYGFTPIETPAVERLEVLQAKGNQGDN 68
Query: 113 LIYDLK---------------DQGGELLSLRYDLTVPFARYLA--MNKLT-NIKRYHIAK 154
+IY L+ D G E +L++D TVP A Y+A +N LT RY +
Sbjct: 69 IIYGLEPILPPNRQAEKDKSGDTGSEARALKFDQTVPLAAYIARHLNDLTFPFARYQMDV 128
Query: 155 VYRRDNPAMTRGRYREFYQCDFDIAGNFD-PMIPDAECLKIMCEILSSLQIGDFLVKVND 213
V+R + GR+R+F QCD D+ G ++ DA+ I+ EI ++ IGDF++++N+
Sbjct: 129 VFRGER--AKDGRFRQFRQCDIDVVGREKLSLLYDAQMPAIITEIFEAVNIGDFVIRINN 186
Query: 214 RRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQ 273
R++L G F +S+++ ++ S +D L+K+ +VK E+ E G+ PE +I D+V+
Sbjct: 187 RKVLTGFFQSLNISETQIKSCISIIDNLEKIGEAKVKLELEKE-GINPEQTQKIIDFVKI 245
Query: 274 HGGVSLVEQLLQ--DPKLSQNKQALEGLGDLKLLFEYLTLFGIDDK-ISFDLSLARGLDY 330
G V V L+ L +++Q G+ +L+ + + G+ DK DL++ARGL+Y
Sbjct: 246 DGSVDDVLDKLKHLSQTLPESEQFNLGVSELETVITGVRNLGVPDKRFCIDLAIARGLNY 305
Query: 331 YTGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIF 390
YTG +YE L+ G E L GS+ +GGRY+ LVG F G K+P VG+SIG+ R+
Sbjct: 306 YTGTVYETTLI------GHEAL--GSICSGGRYEELVGTF--IGEKMPGVGISIGLTRLI 355
Query: 391 SIVEQRL--EALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKL 448
S RL + + T QV+V + Q +L+ LK+ +L AG+ ++K +L
Sbjct: 356 S----RLLKAGILNTLPPTPAQVVVVNMQDELMPTYLKVSQQLRQAGLNVITNFEKR-QL 410
Query: 449 LNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRR 501
Q Q ++ GI IIG E L+ + S E+V+V DL EEIKRR
Sbjct: 411 GKQFQAADKQGIRFCVIIGADEAAAQKSSLKDLQSGEQVEVALADLAEEIKRR 463
>2LW7-A nrPDB
Length = 170
Score = 209 bits (532), Expect = 2e-54, Method: Compositional matrix adjust.
Identities = 108/111 (97%), Positives = 108/111 (97%)
Query: 399 ALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEA 458
ALEEKIRTTETQVLVASAQKKLLEERLKLVSEL DAGIKAELLYKKNPKLLNQLQYCEEA
Sbjct: 60 ALEEKIRTTETQVLVASAQKKLLEERLKLVSELQDAGIKAELLYKKNPKLLNQLQYCEEA 119
Query: 459 GIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQPLCIC 509
GIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQPL I
Sbjct: 120 GIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQPLSIS 170
Score = 112 bits (279), Expect = 5e-25, Method: Compositional matrix adjust.
Identities = 59/60 (98%), Positives = 59/60 (98%)
Query: 2 AERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPKG 61
AERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK
Sbjct: 1 AERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPKA 60
>6NHI-A nrPDB
Length = 457
Score = 209 bits (531), Expect = 3e-54, Method: Compositional matrix adjust.
Identities = 143/465 (30%), Positives = 265/465 (56%), Gaps = 50/465 (10%)
Query: 60 KGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDS-KLIYDLK 118
KGTRD++ ++++ R+ + + + + F+ G + ++TP FE TL GKYGE+ +LI+ +
Sbjct: 15 KGTRDFTAQEVSRRKYIINTLQKNFELFGFQPLETPSFENLSTLTGKYGEEGDRLIFKIL 74
Query: 119 DQGG----------------ELLS------LRYDLTVPFARYLAMN--KLT-NIKRYHIA 153
+ G +L S LRYDLTVPFAR++AMN +LT KRY I
Sbjct: 75 NSGNYTDKVNENDWQNKDAKKLTSQISDKALRYDLTVPFARFVAMNHGQLTFPFKRYQIQ 134
Query: 154 KVYRRDNPAMTRGRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVND 213
V+R D P +GR+REFYQCD D+ G+ + + + E +++ + L + +++N+
Sbjct: 135 PVWRADRPQ--KGRFREFYQCDADVVGS-ESLWQEVELVQLYFKAFKELGV-PVAIQMNN 190
Query: 214 RRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQ 273
R+IL G+ G+++ + ++DKLDK+ + V EM EKG++ E +++ D++
Sbjct: 191 RKILSGLAEYAGITE-QLIDFTVALDKLDKIGKDGVIKEM-QEKGISNEAIEKL-DFL-F 246
Query: 274 HGGVSLVEQLLQ-DPKLSQNKQALEGLGDLKLLFEYLTLFGIDDK-ISFDLSLARGLDYY 331
H ++ +E L + + + ++G+ +L+ + GID++ + F+++LARGLDYY
Sbjct: 247 HQKINALENLQELKTRFEGVEVGIQGVTELEFVLSKAMELGIDNQDLVFNITLARGLDYY 306
Query: 332 TGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFS 391
TG I+E A+ E +GS+ GGRY+ L +F K +P +G+S G++R +
Sbjct: 307 TGAIFEV-----KAKGVE----MGSIGGGGRYNNLTEVFGVK--NIPGIGISFGLDRTYL 355
Query: 392 IVEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQ 451
++E+ L + T + + L A+ ++ E +KL+++L + GI AE LY + KL Q
Sbjct: 356 VMEEL--GLFPENATVKVEYLFANYGEEEAIEAMKLIAQLREKGISAE-LYPEAAKLKKQ 412
Query: 452 LQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVE 496
Y E+ IP + +G+ E+++ + ++++T+ E+ + + + ++
Sbjct: 413 FTYAEKKEIPNLVFLGKDEIENANVTIKNLTTGEQETITQSEFLK 457
>4YRG-A nrPDB
Length = 456
Score = 158 bits (400), Expect = 4e-39, Method: Compositional matrix adjust.
Identities = 131/462 (28%), Positives = 224/462 (48%), Gaps = 38/462 (8%)
Query: 41 LKAQL-GPDESKQKFVLKTP-KGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFE 98
L+AQ GP ++ V P +G RD+ P M R +FDV K G E D PV E
Sbjct: 12 LEAQTQGPGSMQKNMVETEPVQGCRDFPPEAMRCRRHLFDVFHATAKTFGFEEYDAPVLE 71
Query: 99 LKETLMGKYGED-SKLIYDLKDQGGELLSLRYDLTVPFARYL---AMNKLTNIKRYHIAK 154
+E + K GE+ ++ +++ +GG ++LR ++T AR L + L K Y I +
Sbjct: 72 SEELYIRKAGEEITEQMFNFITKGGHRVALRPEMTPSLARLLLGKGRSLLLPAKWYSIPQ 131
Query: 155 VYRRDNPAMTRGRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIG--DFLVKVN 212
+R + A+TRGR RE YQ + DI G + + E + C + SL + D +KVN
Sbjct: 132 CWRYE--AITRGRRREHYQWNMDIVG-VKSVSAEVELVCAACWAMRSLGLSSKDVGIKVN 188
Query: 213 DRRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQ 272
R++L + GV+ KF +C VDK++K+ EEV+ ++ GL P V D I +
Sbjct: 189 SRKVLQTVVEQAGVTSDKFAPVCVIVDKMEKIPREEVEAQL-AVLGLEPTVVDAITTTLS 247
Query: 273 QHGGVSLVEQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYT 332
+ ++++ Q ++ + +A++ +L+ FE + +G D + FD S+ RGL YYT
Sbjct: 248 ----LKSIDEIAQ--RVGEEHEAVK---ELRQFFEQVEAYGYGDWVLFDASVVRGLAYYT 298
Query: 333 GVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSI 392
G+++E + +A + GGRYD L+ + +PC G G I +
Sbjct: 299 GIVFEGFDREGKFRA---------LCGGGRYDNLLTTYGSP-TPIPCAGFGFGDCVIVEL 348
Query: 393 VEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQL 452
++++ L I V++ + + L ++ L DAG A+++ K K++
Sbjct: 349 LQEK--RLLPDIPHVVDDVVI-PFDESMRPHALAVLRRLRDAGRSADIILDKK-KVVQAF 404
Query: 453 QYCEEAGIPLVAIIGEQELKDGVIK---LRSVTSREEVDVRR 491
Y + G ++ +E + G ++ LR T +EE R
Sbjct: 405 NYADRVGAVRAVLVAPEEWERGEVQVKMLREGTGKEEGGAER 446
>3HRI-A nrPDB
Length = 456
Score = 155 bits (391), Expect = 5e-38, Method: Compositional matrix adjust.
Identities = 132/457 (28%), Positives = 218/457 (47%), Gaps = 38/457 (8%)
Query: 41 LKAQL-GPDESKQKFVLKTP-KGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFE 98
L+AQ GP + V P +G RD+ P M +R+ +FDV ++ G E D+PV E
Sbjct: 12 LEAQTQGPGSMQMNMVETEPVQGCRDFPPETMRLRKYLFDVFHSTARKFGFEEYDSPVLE 71
Query: 99 LKETLMGKYGED-SKLIYDLKDQGGELLSLRYDLTVPFARYL---AMNKLTNIKRYHIAK 154
+E + K GE+ ++ +++ +GG ++LR ++T AR L + L K Y I +
Sbjct: 72 SEELYIRKAGEEITEQMFNFITKGGHRVALRPEMTPSLARQLLAKGRSLLLPAKWYSIPQ 131
Query: 155 VYRRDNPAMTRGRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIG--DFLVKVN 212
+R + A+TRGR RE YQ + DI G + + E + C + SL + D VK+N
Sbjct: 132 CWRYE--AITRGRRREHYQWNMDIIG-VKSVSSEVELVCAACTAMQSLGLSSKDVGVKIN 188
Query: 213 DRRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQ 272
R+IL + GVS KF +C VDK++K+ EEV ++ GL V D I +
Sbjct: 189 SRKILQTVVEQAGVSADKFAPVCVIVDKMEKLPREEVVAQLAA-IGLESNVVDAITSTLS 247
Query: 273 QHGGVSLVEQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYT 332
+ ++++ Q ++ + +A+ L D E +G D + FD S+ RGL YYT
Sbjct: 248 ----LKTIDEIAQ--RIGEEHEAVRELRDFITQIE---AYGFGDWVIFDASVVRGLAYYT 298
Query: 333 GVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSI 392
G+++E + ++ GGRYD L+ + VPCVG G I +
Sbjct: 299 GIVFEGF---------DRDGNFRALCGGGRYDNLLTTYGSP-TAVPCVGFGFGDCVIVEL 348
Query: 393 VEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQL 452
+ ++ + L E + LV + + L ++ L DAG A++++ K K++
Sbjct: 349 LNEK-KLLPELHHVVDD--LVIPFDETMRPHALSILRRLRDAGRSADIVFDKK-KVVQAF 404
Query: 453 QYCEEAGIPLVAIIGEQELKDGVIK---LRSVTSREE 486
Y + G ++ E G ++ LR REE
Sbjct: 405 NYADRIGALRAVLVAPDEWARGEVRVKMLREGAGREE 441
>1WU7-A nrPDB
Length = 434
Score = 125 bits (314), Expect = 5e-29, Method: Compositional matrix adjust.
Identities = 119/455 (26%), Positives = 212/455 (46%), Gaps = 59/455 (12%)
Query: 60 KGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDS-KLIYDLK 118
+G RD+ P M V + +F + G ID P E + K GE+ + Y
Sbjct: 10 RGFRDFYPEDMDVEKFIFKTAEEAAEAFGFRRIDFPSLEYLDLYRIKSGEELLQQTYSFV 69
Query: 119 DQGGELLSLRYDLTVPFARYLAMNKLTN--IKRYHIAKVYRRDNPAMTRGRYREFYQCDF 176
D+GG ++L + T R + K ++ Y KV+R + P GRYRE YQ +
Sbjct: 70 DKGGREVTLIPEATPSTVRMVTSRKDLQRPLRWYSFPKVWRYEEPQA--GRYREHYQFNA 127
Query: 177 DIAGNFDPMIPDAECLKIMCEILSSLQIGD-FLVKVNDRRILDGMFAICGVSDSKFRTIC 235
DI G+ P DAE + + IL L + D + +++N R+I++ + I G++ S ++
Sbjct: 128 DIFGSDSPE-ADAEVIALASSILDRLGLQDIYEIRINSRKIMEEI--IGGMTSSDPFSVF 184
Query: 236 SSVDKLDKVSWEEVKNEM----VGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQ 291
S +D+ K+S EE +++ +GE G++ I D G+ + ++ K S+
Sbjct: 185 SIIDRYHKISREEFVDQLRSAGIGEDGVS-----MIADLCSGTRGIDEMARIT--GKSSE 237
Query: 292 NKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEP 351
+ + DL L +G+ + + +D S+ RGL YYTG+++EA +A
Sbjct: 238 EIARMAAVEDL------LASYGVKN-VRYDFSIVRGLSYYTGIVFEAYDRSGQFRA---- 286
Query: 352 LGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQR--LEALEEKIRTTET 409
+ GGRYD L + G VP VG +G + + S++ +R ++ EK
Sbjct: 287 -----ILGGGRYDNLASLM--SGESVPAVGFGMG-DAVISLLLKRENVQIPREKKSVYIC 338
Query: 410 QV------LVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLV 463
+V ++ +KL E + + E+ + G+ A QL+Y G
Sbjct: 339 RVGKINSSIMNEYSRKLRERGMNVTVEIMERGLSA------------QLKYASAIGADFA 386
Query: 464 AIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEI 498
I GE++L+ GV+ +R++ + + +V + +VE +
Sbjct: 387 VIFGERDLERGVVTIRNMYTGSQENVGLDSVVEHL 421
>1X59-A nrPDB
Length = 73
Score = 114 bits (286), Expect = 8e-26, Method: Compositional matrix adjust.
Identities = 60/60 (100%), Positives = 60/60 (100%)
Query: 1 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK 60
MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK
Sbjct: 8 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK 67
>5E3I-A nrPDB
Length = 438
Score = 92.8 bits (229), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 112/450 (24%), Positives = 198/450 (44%), Gaps = 50/450 (11%)
Query: 60 KGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLI----Y 115
KG D P Q A ++ + +G + I P+ E G+ + ++ Y
Sbjct: 16 KGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATDIVEKEMY 75
Query: 116 DLKDQGG--ELLSLRYDLTVPFARYLAMNKL---TNIKRYHIAKVYRRDNPAMTRGRYRE 170
D+G E L+LR + T R L + L + +++ ++R + P +GRYR+
Sbjct: 76 TFFDKGNPPESLTLRPEGTAGCVRALVEHNLLRGATPRVWYMGPMFRYEKP--QKGRYRQ 133
Query: 171 FYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSD-- 228
F+Q + G P I DAE + + + + + D +V++ G +D
Sbjct: 134 FHQFGVETFGVATPDI-DAELIMLTARLWKRMGV-DHMVQLE--------LNTLGETDER 183
Query: 229 SKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQD-P 287
+++R + K + +E + L RI D + +++L++ P
Sbjct: 184 TEYRNALVAFLNEHKDALDEDSQRRLTTNPL------RILD-----SKIESTQKILENAP 232
Query: 288 KLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQA 347
KL + + L + L +YLT GI K + L RGLDYY ++E +Q
Sbjct: 233 KLHDFLKE-DSLSHFQQLQDYLTAAGI--KFVINQKLVRGLDYYNKTVFEWTTTALGSQ- 288
Query: 348 GEEPLGVGSVAAGGRYDGLVGMFDPKG-RKVPCVGLSIGVERIFSIVEQRLEALEEKIRT 406
G+V AGGRYDGLVG K + VP VG ++G+ER+ ++EQ +A E +R
Sbjct: 289 -------GTVCAGGRYDGLVGQLKGKADQSVPAVGFAMGMERLLLLLEQVEQA--EIVRD 339
Query: 407 TETQVLVASA-QKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAI 465
E ++ A Q K L +L +L A + + +Q++ ++AG I
Sbjct: 340 CEAFLVAEPAYQSKALVLAEQLRDQLEAANSNIRIKTGSQGSMKSQMKKADQAGAVYAII 399
Query: 466 IGEQELKDGVIKLRSVTSREEVDVRREDLV 495
+GE+E + + ++ + + E+ V +LV
Sbjct: 400 LGEREWEAQQLAVKELATAEQSQVALAELV 429
>1ADJ-A nrPDB
Length = 421
Score = 89.4 bits (220), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 111/467 (23%), Positives = 199/467 (42%), Gaps = 93/467 (19%)
Query: 60 KGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLI----Y 115
+GT+D +++ + +++ + + GA + TP+FE + G + ++ +
Sbjct: 7 RGTKDLFGKELRMHQRIVATARKVLEAAGALELVTPIFEETQVFEKGVGAATDIVRKEMF 66
Query: 116 DLKDQGGELLSLRYDLTVPFARYLAMNKL----TNIKRYHIAKVYRRDNPAMTRGRYREF 171
+D+GG L+LR + T R + + ++ + ++R + P +GRYR+F
Sbjct: 67 TFQDRGGRSLTLRPEGTAAMVRAYLEHGMKVWPQPVRLWMAGPMFRAERP--QKGRYRQF 124
Query: 172 YQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVND--------------RRIL 217
+Q +++ G+ +P++ DAE + ++ E L L + VK++ R +L
Sbjct: 125 HQVNYEALGSENPIL-DAEAVVLLYECLKELGLRRLKVKLSSVGDPEDRARYNAYLREVL 183
Query: 218 DGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGV 277
DSK R + + LD S E ++ E G+ P + D +G+ + H
Sbjct: 184 SPHREALS-EDSKERLEENPMRILDSKS--ERDQALLKELGVRP-MLDFLGEEARAH--- 236
Query: 278 SLVEQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDL--SLARGLDYYTGVI 335
L + ++ LE L + ++L +L RGLDYY
Sbjct: 237 -----------LKEVERHLERL-----------------SVPYELEPALVRGLDYYVRTA 268
Query: 336 YEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQ 395
+E + AQ+ ++ GGRYDGL + G +VP VG + GVER+ +E
Sbjct: 269 FEVHHEEIGAQS--------ALGGGGRYDGLSELLG--GPRVPGVGFAFGVERVALALEA 318
Query: 396 RLEALEEK-------IRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNP-K 447
L E+ I TE V A + L RL+ AE Y P K
Sbjct: 319 EGFGLPEEKGPDLYLIPLTEEAVAEAFYLAEALRPRLR-----------AE--YALAPRK 365
Query: 448 LLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDL 494
L+ + G +GE EL+ G + L+ + + E+V + RE++
Sbjct: 366 PAKGLEEALKRGAAFAGFLGEDELRAGEVTLKRLATGEQVRLSREEV 412
>1QE0-A nrPDB
Length = 420
Score = 87.8 bits (216), Expect = 9e-18, Method: Compositional matrix adjust.
Identities = 105/462 (22%), Positives = 193/462 (41%), Gaps = 58/462 (12%)
Query: 55 VLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLI 114
++K P+GT+D P + + + + + I TP+FE + G+ + ++
Sbjct: 1 MIKIPRGTQDILPEDSKKWRYIENQLDELMTFYNYKEIRTPIFESTDLFARGVGDSTDVV 60
Query: 115 ----YDLKDQGGELLSLRYDLTVPFARYLAMNKLTN-----IKRYHIAKVYRRDNPAMTR 165
Y KD+G ++LR + T R +K+ IK Y+ ++R + +
Sbjct: 61 QKEMYTFKDKGDRSITLRPEGTAAVVRSYIEHKMQGNPNQPIKLYYNGPMFRYERKQ--K 118
Query: 166 GRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVND-------RRILD 218
GRYR+F Q + G +P + DAE L ++ I S + + +N + +
Sbjct: 119 GRYRQFNQFGVEAIGAENPSV-DAEVLAMVMHIYQSFGLKHLKLVINSVGDMASRKEYNE 177
Query: 219 GMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVS 278
+ +F + C S D + + K V A + A RI D++ + +
Sbjct: 178 ALVKHFEPVIHEFCSDCQSRLHTDPMRILDCK---VDRDKEAIKTAPRITDFLNEESK-A 233
Query: 279 LVEQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEA 338
EQ+ YL GI + D +L RGLDYYT +E
Sbjct: 234 YYEQVKA----------------------YLDDLGI--PYTEDPNLVRGLDYYTHTAFE- 268
Query: 339 VLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLE 398
+++ P G + ++ GGRY+GL+ + D LSI + E
Sbjct: 269 LMMDNPNYDG----AITTLCGGGRYNGLLELLDGPSETGIGFALSIERLLLALEEEGIEL 324
Query: 399 ALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEA 458
+EE + + + + + +KL++ L GIKA+ Y + K+ Q++ +
Sbjct: 325 DIEENL-----DLFIVTMGDQADRYAVKLLNHLRHNGIKADKDYLQR-KIKGQMKQADRL 378
Query: 459 GIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKR 500
G +IG+QEL++ I ++++T+ E + + LVE K+
Sbjct: 379 GAKFTIVIGDQELENNKIDVKNMTTGESETIELDALVEYFKK 420
>3RAC-A nrPDB
Length = 373
Score = 86.7 bits (213), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 98/372 (26%), Positives = 173/372 (46%), Gaps = 42/372 (11%)
Query: 49 ESKQKFVLKTP---KGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLM- 104
E+ + F + P G D++ R+ AV ++ + + G E + + +FE +TL+
Sbjct: 17 EAVRGFADRPPGMQDGYPDFAKRRRAVETRLLSFV----EDAGYEPVTSGLFEYVDTLLR 72
Query: 105 GKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLA---MNKLTNIKRYHIAKVYRR-DN 160
+ E S+ L D GG+ ++LR ++T AR A T I+ + +VYRR D+
Sbjct: 73 ARSPESSRDWIRLFDGGGDAVALRPEMTPSIARMAAPRVAAGRTPIRWCYCERVYRRTDD 132
Query: 161 PA---MTRGRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRIL 217
PA G+ E Q + G + D + L+++ E ++ + + V+ R++
Sbjct: 133 PASLSWASGKAAESTQVGIERIGEEASVDVDMDVLRLLHEASAAAGVRHHRIVVSHARLV 192
Query: 218 DGMFAICGVSDSKFRTICSSVDKLDKVSWEEV------KNEMVGEKGLAPEVADRIGDYV 271
+ G+S S R + + + V + E+ K+ + L A+R
Sbjct: 193 PRLLDALGISASLSRAFLACLTSGNYVQFRELWQLHAAKDVDLLANLLTWSPAERDAAKR 252
Query: 272 QQHGGVSLVEQLLQD---PKLSQNKQALEGLGDLKLLFEYLTLFGI-DDKISFDLSLARG 327
+ +E LL+D P+ + + + + L L E L G+ D ++FDL+L R
Sbjct: 253 SREASDRELEALLRDAVDPRAAADVR--DAWRYLCRLAEALHDSGLASDVVTFDLALHRE 310
Query: 328 LDYYTGVIYEAVLLQTPAQAGEEPLGVGS-VAAGGRYDGLVGMFDPKGRKVPCVGLSIGV 386
LDYYTG+++E + P GVG+ +A GGRYD L+ F G P VG + V
Sbjct: 311 LDYYTGLVFE---MFAP--------GVGAPIAQGGRYDELLAQF---GAGAPAVGFAFEV 356
Query: 387 ERIFSIVEQRLE 398
ER+ +++E + E
Sbjct: 357 ERVMAVLEAQEE 368
>2EL9-A nrPDB
Length = 431
Score = 86.3 bits (212), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 112/470 (23%), Positives = 200/470 (42%), Gaps = 80/470 (17%)
Query: 60 KGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLI----Y 115
+G DY P + A+ +++ + +G I P+ E GE + ++ Y
Sbjct: 16 RGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFKRAIGEVTDVVEKEMY 75
Query: 116 DLKDQGGELLSLRYDLTVPFARY-LAMNKLTNIKR--YHIAKVYRRDNPAMTRGRYREFY 172
+D+ G+ L+LR + T R + L N ++ ++I ++R + P +GRYR+F+
Sbjct: 76 TFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRHERP--QKGRYRQFH 133
Query: 173 QCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFL-VKVNDRRILDGMFAICGVSDSKF 231
Q ++ G P I DAE + + +L I + + +++N + + A D+
Sbjct: 134 QLGCEVFGLQGPDI-DAELIMLTARWWRALGISEHVTLELNS---IGSLEARANYRDALV 189
Query: 232 RTICSSVDKLDKVSWEEVKNEMVGEK-----GLAPEV------ADRIGDYVQQHGGVSLV 280
+ +KLD E+ K M PEV A +GDY+ +
Sbjct: 190 AFLEQHKEKLD----EDCKRRMYTNPLRVLDSKNPEVQALLNDAPALGDYLDE------- 238
Query: 281 EQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVL 340
++++ GL KLL + ++ + L RGLDYY ++E V
Sbjct: 239 ----------ESREHFAGL--CKLLESAGIAYTVNQR------LVRGLDYYNRTVFEWVT 280
Query: 341 LQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEAL 400
+Q G+V AGGRYDGLV GR P VG ++G+ER+ +V +A+
Sbjct: 281 NSLGSQ--------GTVCAGGRYDGLVEQLG--GRATPAVGFAMGLERLVLLV----QAV 326
Query: 401 EEKIRTTETQ--VLVAS-----AQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQ 453
+ + LVAS + L ERL+ EL G+K + Q
Sbjct: 327 NPEFKADPVVDIYLVASGADTQSAAMALAERLR--DEL--PGVKL-MTNHGGGNFKKQFA 381
Query: 454 YCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTG 503
++ G + ++GE E+ +G ++ + S E+ V ++ + ++ G
Sbjct: 382 RADKWGARVAVVLGESEVANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG 431
>3OD1-A nrPDB
Length = 400
Score = 80.1 bits (196), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 82/342 (23%), Positives = 146/342 (42%), Gaps = 36/342 (10%)
Query: 54 FVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKL 113
F+ + P G RD P ++ + D + G ++I+TP E ET+ +
Sbjct: 8 FMFEKPFGMRDTLPEWYKTKKNICDQMTEEINLWGYDMIETPTLEYYETVGVVSAILDQQ 67
Query: 114 IYDLKDQGGELLSLRYDLTVPFARYLAM---NKLTNIKRYHIAKVYRRDNPAMTRGRYRE 170
++ L DQ G L LR D+T P AR +A ++ ++ + + VYR G+ E
Sbjct: 68 LFKLLDQQGNTLVLRPDMTAPIARLVASSLKDRAYPLRLAYQSNVYRAQQN--EGGKPAE 125
Query: 171 FYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSK 230
F Q ++ G+ D E + +M L + +F V + ++ + ++ +
Sbjct: 126 FEQLGVELIGD-GTASADGEVIALMIAALKRAGLSEFKVAIGHVGYVNALLMDVVGNEQR 184
Query: 231 FRTICSSVDKLDKVSWEEVKN-----EMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQ 285
D+L + +E KN E V L+ R+ + + GG + +E+
Sbjct: 185 -------ADRLRRFLYE--KNYVGYREHVKSLNLSTIDKSRLMNLLSLRGGRAAIEEA-- 233
Query: 286 DPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPA 345
L Q ++ L ++ L+E L +G + + FDL+L + YYTGV++E
Sbjct: 234 -RGLIQTEKGKTALAEMTKLYEVLESYGASEYVKFDLTLVLHMSYYTGVVFEGY------ 286
Query: 346 QAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVE 387
LGV + +GGRYD L+ F R G + ++
Sbjct: 287 ---GNRLGV-PLCSGGRYDELLSKFH---RPAQATGFGVRID 321
>4E51-A nrPDB
Length = 467
Score = 75.9 bits (185), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 102/443 (23%), Positives = 189/443 (42%), Gaps = 69/443 (15%)
Query: 60 KGTRDYSPRQMAVREKVFDVIIRCFKR-HGAEVIDTPVFELKETLMGKYGEDSKLI---- 114
KG D P+ + E F+ ++ R +G + I TP+ E GE + ++
Sbjct: 36 KGMNDILPQDAGLWE-FFEATVKSLLRAYGYQNIRTPIVEHTPLFTRGIGEVTDIVEKEM 94
Query: 115 YDLKDQ-GGELLSLRYDLTVPFARY-LAMNKLTNIKR--YHIAKVYRRDNPAMTRGRYRE 170
Y D GE L+LR + T R + N L + + ++I ++R + P RGRYR+
Sbjct: 95 YSFVDALNGENLTLRPENTAAVVRAAIEHNMLYDGPKRLWYIGPMFRHERP--QRGRYRQ 152
Query: 171 FYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSK 230
F+Q + G P DAE + + + L + +++N G+++ +
Sbjct: 153 FHQVGVEALGFAGP-DADAEIVMMCQRLWEDLGLTGIKLEINS----------LGLAEER 201
Query: 231 FRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQL-LQDPKL 289
+ +++ + + E + AD++ D Q+ + + L ++P L
Sbjct: 202 ------AAHRVELIKYLE-------------QHADKLDDDAQRRLYTNPLRVLDTKNPAL 242
Query: 290 SQ----NKQALEGLGDL-KLLFEYLTLFGIDDKISFDLS--LARGLDYYTGVIYEAVLLQ 342
+ + ++ LGD+ + FE L + + F ++ L RGLDYY ++E V +
Sbjct: 243 QEIVRNAPKLIDFLGDVSRAHFEGLQRLLKANNVPFTINPRLVRGLDYYNLTVFEWVTDK 302
Query: 343 TPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIV-EQRLEALE 401
AQ G+VAAGGRYD L+ G+ G ++G+ERI ++ E+ L +
Sbjct: 303 LGAQ--------GTVAAGGRYDPLIEQL--GGKPTAACGWAMGIERILELLKEEHLVPEQ 352
Query: 402 EKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKN---PKLLNQLQYCEEA 458
E + V V E+ + L D G+ L + +Q++ + +
Sbjct: 353 EGV-----DVYVVHQGDAAREQAFIVAERLRDTGLDVILHCSADGAGASFKSQMKRADAS 407
Query: 459 GIPLVAIIGEQELKDGVIKLRSV 481
G I GE E+ +G ++ +
Sbjct: 408 GAAFAVIFGEDEVTNGTASVKPL 430
>1Z7M-A nrPDB
Length = 344
Score = 48.9 bits (115), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 61/270 (22%), Positives = 116/270 (42%), Gaps = 35/270 (12%)
Query: 105 GKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRY-HIAKVYRRDNPAM 163
GK K+ +K +G + ++LRYD T+P R + K + RY + K++R++
Sbjct: 76 GKTFNQEKMFQFIKHEG-QSITLRYDFTLPLVRLYSQIKDSTSARYSYFGKIFRKEKRH- 133
Query: 164 TRGRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAI 223
+GR E YQ ++ G + E L + +++ L + + ++ + +
Sbjct: 134 -KGRSTENYQIGIELFGE-SADKSELEILSLALQVIEQLGLNKTVFEIGSAKFFQ---RL 188
Query: 224 CGVSDSKFRTICSSVDKLDKVSWEEV--KNEMVGE-KGLAPEVADRIGDYVQQHGGVSLV 280
C ++D + + K D KN E +GL E+ ++ +S +
Sbjct: 189 CQLADGSTELLTELLLKKDLSGLNAFIEKNNFSKELRGLLKEI------FITNE--LSRL 240
Query: 281 EQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVL 340
E L+ + K + + LK E L++ I DL + +DYYT ++++A
Sbjct: 241 ENLVTNTK---DDVLISSFDQLKEFSEKLSMI---KPIIIDLGMVPKMDYYTDLMFKAY- 293
Query: 341 LQTPAQAGEEPLGVGSVAAGGRYDGLVGMF 370
+ A +P + +GGRYD L+ F
Sbjct: 294 ----SSAANQP-----ILSGGRYDQLLSNF 314
>6FUA-A nrPDB
Length = 388
Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 73/345 (21%), Positives = 144/345 (41%), Gaps = 43/345 (12%)
Query: 59 PKGTRDY----SPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSK-L 113
P G D + +Q +R ++ +I HG +++ P+ E E+L+ ED K
Sbjct: 4 PDGVADVLFEDAHKQEVLRHQLTQQLIT----HGYQLVSPPMIEFTESLLSGASEDLKRQ 59
Query: 114 IYDLKDQ-GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFY 172
+ + DQ G L+ +R D+T R A + I RY A P+ G R
Sbjct: 60 TFKIIDQLTGRLMGIRADITPQILRIDAHHGGDGIARYCYAGDVIHTLPSGLFGS-RTPL 118
Query: 173 QCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFL-VKVNDRRILDGMFAICGVSDSKF 231
Q +I G + + D E + ++ +++SL + L V + I + + +S
Sbjct: 119 QLGAEIFG-CESIAADIELIDVLFSMINSLDMSAVLHVDLGHVTIFKRLAELAALS---- 173
Query: 232 RTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVAD-----RIGDYVQQHGGVSLVEQLLQD 286
S ++L ++ + E+ + P +D R G H +L+ +L ++
Sbjct: 174 ---ASDTEQLMQLYANKNLPELKQVCQVLPMGSDFYTLARFG-----HDIANLLGRLSEN 225
Query: 287 PKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQ 346
+ Q+ + + + +L+ L +L + +S D++ G Y+TG+++ +
Sbjct: 226 AQ--QDTKIVTAIDELQRLKAHLQV-QWQCAVSIDVTELSGYHYHTGIVFNGYI-----N 277
Query: 347 AGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFS 391
+ +PL GGR+DG+ + G S+ V R+ +
Sbjct: 278 SETQPL-----VRGGRFDGMKSNQLATNQPRQATGFSMDVSRLLA 317
>1F8S-A nrPDB
Length = 498
Score = 35.8 bits (81), Expect = 0.046, Method: Compositional matrix adjust.
Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 13/121 (10%)
Query: 232 RTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGG--VSLVEQLLQDPKL 289
RT CS + L+K K ++ E L+P D IGD + + G VS +E L D
Sbjct: 170 RTNCSYI--LNKYDTYSTKEYLIKEGDLSPGAVDMIGDLLNEDSGYYVSFIESLKHDDIF 227
Query: 290 SQNK---QALEGLGDLKLLFEYLTLFGIDDKISFDLSLAR--GLDYYTGVIYEAVLLQTP 344
+ K + ++G+ L I DK+ F+ + + D V+YE + +TP
Sbjct: 228 AYEKRFDEIVDGMDKLPTAM----YRDIQDKVHFNAQVIKIQQNDQKVTVVYETLSKETP 283
Query: 345 A 345
+
Sbjct: 284 S 284
>3KVE-A nrPDB
Length = 486
Score = 35.4 bits (80), Expect = 0.064, Method: Compositional matrix adjust.
Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 8/115 (6%)
Query: 232 RTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGG--VSLVEQLLQDPKL 289
RT CS + L+K K ++ E L+P D IGD + + G VS +E L D
Sbjct: 170 RTNCSYI--LNKYDTYSTKEYLIKEGNLSPGAVDMIGDLLNEDSGYYVSFIESLKHDDIF 227
Query: 290 SQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTP 344
+ K+ E +G + L + I++K+ F+ AR + V QTP
Sbjct: 228 AYEKRFDEIVGGMDQLPTSMYR-AIEEKVKFN---ARVIKIQQNANQVTVTYQTP 278
>2DJV-A nrPDB
Length = 79
Score = 33.5 bits (75), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 24/48 (50%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
Query: 4 RAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESK 51
+A ++E+ K QG VR LK QKA + EVAKLL LK QL E K
Sbjct: 16 QALMDEVTK-QGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGK 62
>1REO-A nrPDB
Length = 486
Score = 31.6 bits (70), Expect = 0.88, Method: Compositional matrix adjust.
Identities = 24/76 (31%), Positives = 35/76 (46%), Gaps = 4/76 (5%)
Query: 232 RTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGG--VSLVEQLLQDPKL 289
RT CS + L+K K ++ E L+P D IGD + + G VS E L D
Sbjct: 170 RTNCSYI--LNKYDTYSTKEYLLKEGNLSPGAVDMIGDLMNEDSGYYVSFPESLRHDDIF 227
Query: 290 SQNKQALEGLGDLKLL 305
+ K+ E +G + L
Sbjct: 228 AYEKRFDEIVGGMDKL 243
>5XIL-A nrPDB
Length = 512
Score = 30.0 bits (66), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 29/119 (24%), Positives = 51/119 (42%), Gaps = 12/119 (10%)
Query: 381 GLSIGVERIFSIVEQRLEALEEKIRTTETQVLVAS----------AQKKLLEERLKLVSE 430
GLS V + +V + R TQV++ A+++LL +L SE
Sbjct: 263 GLSTRVIGVMIMVHGDNRGMVMPPRVASTQVIIIPVGITKDTTEEARQELLASCWRLESE 322
Query: 431 LWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDG--VIKLRSVTSREEV 487
L + G++A + N + + E G+PL +G +EL + + +R +R V
Sbjct: 323 LCEGGVRARCDLRDNYSPGWRFNHWEVKGVPLRVELGPRELAERSLAVAVRHSGARHSV 381
>5Z50-A nrPDB
Length = 237
Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 10/63 (15%)
Query: 251 NEMVGEKGLAPEV------ADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLGDLKL 304
+E ++GL P+V AD I YV+ GV +V + DPKL + L D
Sbjct: 121 DEAFSQRGLVPKVVFTAADADVIKTYVRLGLGVGIVAHMAVDPKLDNDLVIL----DASH 176
Query: 305 LFE 307
LFE
Sbjct: 177 LFE 179
>1SGM-A nrPDB
Length = 191
Score = 29.3 bits (64), Expect = 4.8, Method: Compositional matrix adjust.
Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 6/51 (11%)
Query: 231 FRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQ--HGGVSL 279
RT+C V K SWE V + E G A E A+++G + GG+ L
Sbjct: 120 LRTVCMKVFK----SWEAVFARKLMENGFAEEEANQLGTLINSMIEGGIML 166
>5Z5E-A nrPDB
Length = 534
Score = 28.9 bits (63), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 13/44 (29%), Positives = 24/44 (54%)
Query: 455 CEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEI 498
+E G+P I Q L+D + +R + ++V V+ EDL ++
Sbjct: 486 VDEIGVPYAITIDYQTLEDNTVTIRDRDTMKQVRVKIEDLPNQL 529
>3A31-A nrPDB
Length = 471
Score = 28.5 bits (62), Expect = 6.9, Method: Compositional matrix adjust.
Identities = 48/246 (19%), Positives = 99/246 (40%), Gaps = 41/246 (16%)
Query: 51 KQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETL----MGK 106
++F T G +S +R + +V+ + R G V++TP+ E +
Sbjct: 30 NREFATFTGAGVPLFSLGGGPIRYALAEVLAKFHARRGYYVVETPIIASTELFKVSGHIE 89
Query: 107 YGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLTN--------IKRYHIAKVYRR 158
+ ++ ++D++ G +++ + P+ L +N++ K + +V+R
Sbjct: 90 FYRNNMYLFDIE---GHEFAVK-PMNCPYHILLFLNEVAKHRSKLPLPFKVFEFGRVHRY 145
Query: 159 DNPAMTRG--RYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRI 216
+ G R R F Q D I ++P + ++ ++ +++ +
Sbjct: 146 EPSGSIYGLLRVRGFTQDDAHI------IVPGGRVIDVVYDVFEEMKL-----------V 188
Query: 217 LDGMFAICGVSDSKFRTICSSVDK-LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHG 275
L+ +F + GVS F+ S DK L + K E G + E A RI +
Sbjct: 189 LERLFKL-GVSSETFKVRLSMSDKSLIGKEFMGSKEEWEGAEEALREAASRI----NEKY 243
Query: 276 GVSLVE 281
G+ +VE
Sbjct: 244 GIDIVE 249
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
4X5O-A nrPDB 650 0.0
5W6M-A nrPDB 550 e-157
4YRG-A nrPDB 415 e-116
3HRI-A nrPDB 414 e-116
3NET-A nrPDB 396 e-110
1QE0-A nrPDB 374 e-104
6NHI-A nrPDB 359 2e-99
1WU7-A nrPDB 356 2e-98
2EL9-A nrPDB 354 6e-98
5E3I-A nrPDB 352 2e-97
4E51-A nrPDB 342 2e-94
1ADJ-A nrPDB 281 6e-76
3OD1-A nrPDB 275 2e-74
3RAC-A nrPDB 271 6e-73
1Z7M-A nrPDB 188 5e-48
2LW7-A nrPDB 119 4e-27
1X59-A nrPDB 98 7e-21
Sequences not found previously or not previously below threshold:
6FUA-A nrPDB 116 2e-26
2I4O-A nrPDB 68 1e-11
1NYR-A nrPDB 66 4e-11
1USY-C nrPDB 54 1e-07
1NJ8-A nrPDB 47 2e-05
6JP2-A nrPDB 47 2e-05
3A31-A nrPDB 47 2e-05
6NAB-A nrPDB 44 2e-04
5Z5E-A nrPDB 43 2e-04
4K87-A nrPDB 43 2e-04
6MN8-A nrPDB 42 8e-04
1B76-A nrPDB 41 0.001
1NJ2-A nrPDB 41 0.001
5W25-A nrPDB 41 0.002
1ATI-A nrPDB 41 0.002
4P3N-A nrPDB 40 0.002
3WRZ-A nrPDB 40 0.003
3VQX-A nrPDB 39 0.005
1IL2-A nrPDB 38 0.010
5XIL-A nrPDB 38 0.012
4WJ3-M nrPDB 37 0.022
4RMF-A nrPDB 37 0.025
2ZNJ-A nrPDB 36 0.029
1WLE-A nrPDB 36 0.031
2DU7-A nrPDB 36 0.060
5XIP-A nrPDB 35 0.090
2DJV-A nrPDB 35 0.10
5XIG-A nrPDB 34 0.12
2ODR-C nrPDB 33 0.37
6M7Z-A nrPDB 32 0.41
1CRU-A nrPDB 32 0.49
4NCX-A nrPDB 32 0.53
5IJN-G nrPDB 31 1.1
3A74-A nrPDB 31 1.9
5ZG8-A nrPDB 30 2.2
6OTE-A nrPDB 30 2.4
3MMP-A nrPDB 29 6.1
5OQL-Y nrPDB 28 7.7
>4X5O-A nrPDB
Length = 509
Score = 650 bits (1677), Expect = 0.0, Method: Composition-based stats.
Identities = 509/509 (100%), Positives = 509/509 (100%)
Query: 1 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK 60
MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK
Sbjct: 1 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK 60
Query: 61 GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQ 120
GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQ
Sbjct: 61 GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQ 120
Query: 121 GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAG 180
GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAG
Sbjct: 121 GGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAG 180
Query: 181 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK 240
NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK
Sbjct: 181 NFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDK 240
Query: 241 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG 300
LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG
Sbjct: 241 LDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLG 300
Query: 301 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG 360
DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG
Sbjct: 301 DLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAG 360
Query: 361 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL 420
GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL
Sbjct: 361 GRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKL 420
Query: 421 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS 480
LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS
Sbjct: 421 LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRS 480
Query: 481 VTSREEVDVRREDLVEEIKRRTGQPLCIC 509
VTSREEVDVRREDLVEEIKRRTGQPLCIC
Sbjct: 481 VTSREEVDVRREDLVEEIKRRTGQPLCIC 509
>5W6M-A nrPDB
Length = 450
Score = 550 bits (1417), Expect = e-157, Method: Composition-based stats.
Identities = 449/450 (99%), Positives = 450/450 (100%)
Query: 54 FVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKL 113
FVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKL
Sbjct: 1 FVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKL 60
Query: 114 IYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQ 173
IYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQ
Sbjct: 61 IYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQ 120
Query: 174 CDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRT 233
C+FDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRT
Sbjct: 121 CEFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRT 180
Query: 234 ICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNK 293
ICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNK
Sbjct: 181 ICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNK 240
Query: 294 QALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLG 353
QALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLG
Sbjct: 241 QALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLG 300
Query: 354 VGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLV 413
VGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLV
Sbjct: 301 VGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLV 360
Query: 414 ASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKD 473
ASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKD
Sbjct: 361 ASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKD 420
Query: 474 GVIKLRSVTSREEVDVRREDLVEEIKRRTG 503
GVIKLRSVTSREEVDVRREDLVEEIKRRTG
Sbjct: 421 GVIKLRSVTSREEVDVRREDLVEEIKRRTG 450
>4YRG-A nrPDB
Length = 456
Score = 415 bits (1067), Expect = e-116, Method: Composition-based stats.
Identities = 128/462 (27%), Positives = 222/462 (48%), Gaps = 38/462 (8%)
Query: 41 LKAQL-GPDESKQKFVLKTP-KGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFE 98
L+AQ GP ++ V P +G RD+ P M R +FDV K G E D PV E
Sbjct: 12 LEAQTQGPGSMQKNMVETEPVQGCRDFPPEAMRCRRHLFDVFHATAKTFGFEEYDAPVLE 71
Query: 99 LKETLMGKYGED-SKLIYDLKDQGGELLSLRYDLTVPFARYL---AMNKLTNIKRYHIAK 154
+E + K GE+ ++ +++ +GG ++LR ++T AR L + L K Y I +
Sbjct: 72 SEELYIRKAGEEITEQMFNFITKGGHRVALRPEMTPSLARLLLGKGRSLLLPAKWYSIPQ 131
Query: 155 VYRRDNPAMTRGRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIG--DFLVKVN 212
+R + A+TRGR RE YQ + DI G + + E + C + SL + D +KVN
Sbjct: 132 CWRYE--AITRGRRREHYQWNMDIVG-VKSVSAEVELVCAACWAMRSLGLSSKDVGIKVN 188
Query: 213 DRRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQ 272
R++L + GV+ KF +C VDK++K+ EEV+ ++ GL P V D I +
Sbjct: 189 SRKVLQTVVEQAGVTSDKFAPVCVIVDKMEKIPREEVEAQL-AVLGLEPTVVDAITTTLS 247
Query: 273 QHGGVSLVEQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYT 332
+ ++++ Q ++ + + + +L+ FE + +G D + FD S+ RGL YYT
Sbjct: 248 ----LKSIDEIAQ--RVGEEHE---AVKELRQFFEQVEAYGYGDWVLFDASVVRGLAYYT 298
Query: 333 GVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSI 392
G+++E + +A + GGRYD L+ + +PC G G I +
Sbjct: 299 GIVFEGFDREGKFRA---------LCGGGRYDNLLTTYGSP-TPIPCAGFGFGDCVIVEL 348
Query: 393 VEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQL 452
++++ L I V++ + + L ++ L DAG A+++ K K++
Sbjct: 349 LQEK--RLLPDIPHVVDDVVI-PFDESMRPHALAVLRRLRDAGRSADIILDKK-KVVQAF 404
Query: 453 QYCEEAGIPLVAIIGEQELKDGVIKLR---SVTSREEVDVRR 491
Y + G ++ +E + G ++++ T +EE R
Sbjct: 405 NYADRVGAVRAVLVAPEEWERGEVQVKMLREGTGKEEGGAER 446
>3HRI-A nrPDB
Length = 456
Score = 414 bits (1064), Expect = e-116, Method: Composition-based stats.
Identities = 128/462 (27%), Positives = 218/462 (47%), Gaps = 38/462 (8%)
Query: 41 LKAQL-GPDESKQKFVLKTP-KGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFE 98
L+AQ GP + V P +G RD+ P M +R+ +FDV ++ G E D+PV E
Sbjct: 12 LEAQTQGPGSMQMNMVETEPVQGCRDFPPETMRLRKYLFDVFHSTARKFGFEEYDSPVLE 71
Query: 99 LKETLMGKYGED-SKLIYDLKDQGGELLSLRYDLTVPFARYL---AMNKLTNIKRYHIAK 154
+E + K GE+ ++ +++ +GG ++LR ++T AR L + L K Y I +
Sbjct: 72 SEELYIRKAGEEITEQMFNFITKGGHRVALRPEMTPSLARQLLAKGRSLLLPAKWYSIPQ 131
Query: 155 VYRRDNPAMTRGRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIG--DFLVKVN 212
+R + A+TRGR RE YQ + DI G + + E + C + SL + D VK+N
Sbjct: 132 CWRYE--AITRGRRREHYQWNMDIIG-VKSVSSEVELVCAACTAMQSLGLSSKDVGVKIN 188
Query: 213 DRRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQ 272
R+IL + GVS KF +C VDK++K+ EEV ++ GL V D I +
Sbjct: 189 SRKILQTVVEQAGVSADKFAPVCVIVDKMEKLPREEVVAQL-AAIGLESNVVDAITSTLS 247
Query: 273 QHGGVSLVEQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYT 332
+ ++++ Q ++ + + + +L+ + +G D + FD S+ RGL YYT
Sbjct: 248 ----LKTIDEIAQ--RIGEEHE---AVRELRDFITQIEAYGFGDWVIFDASVVRGLAYYT 298
Query: 333 GVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSI 392
G+++E +A + GGRYD L+ + VPCVG G I +
Sbjct: 299 GIVFEGFDRDGNFRA---------LCGGGRYDNLLTTYGSP-TAVPCVGFGFGDCVIVEL 348
Query: 393 VEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQL 452
+ ++ L ++ LV + + L ++ L DAG A++++ K K++
Sbjct: 349 LNEKK--LLPELHHVVDD-LVIPFDETMRPHALSILRRLRDAGRSADIVFDKK-KVVQAF 404
Query: 453 QYCEEAGIPLVAIIGEQELKDGVIKLR---SVTSREEVDVRR 491
Y + G ++ E G ++++ REE R
Sbjct: 405 NYADRIGALRAVLVAPDEWARGEVRVKMLREGAGREEGANER 446
>3NET-A nrPDB
Length = 465
Score = 396 bits (1016), Expect = e-110, Method: Composition-based stats.
Identities = 151/472 (31%), Positives = 245/472 (51%), Gaps = 38/472 (8%)
Query: 53 KFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSK 112
K TP G ++ P + + + D I R ++ +G I+TP E E L K +
Sbjct: 9 KINFSTPSGFPEFLPSEKRLELYLLDTIRRVYESYGFTPIETPAVERLEVLQAKGNQGDN 68
Query: 113 LIYDLK---------------DQGGELLSLRYDLTVPFARYLAMN---KLTNIKRYHIAK 154
+IY L+ D G E +L++D TVP A Y+A + RY +
Sbjct: 69 IIYGLEPILPPNRQAEKDKSGDTGSEARALKFDQTVPLAAYIARHLNDLTFPFARYQMDV 128
Query: 155 VYRRDNPAMTRGRYREFYQCDFDIAGNFD-PMIPDAECLKIMCEILSSLQIGDFLVKVND 213
V+R + GR+R+F QCD D+ G ++ DA+ I+ EI ++ IGDF++++N+
Sbjct: 129 VFRGER--AKDGRFRQFRQCDIDVVGREKLSLLYDAQMPAIITEIFEAVNIGDFVIRINN 186
Query: 214 RRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQ 273
R++L G F +S+++ ++ S +D L+K+ +VK E+ E G+ PE +I D+V+
Sbjct: 187 RKVLTGFFQSLNISETQIKSCISIIDNLEKIGEAKVKLELEKE-GINPEQTQKIIDFVKI 245
Query: 274 HGGVSLVEQLLQ--DPKLSQNKQALEGLGDLKLLFEYLTLFGIDDK-ISFDLSLARGLDY 330
G V V L+ L +++Q G+ +L+ + + G+ DK DL++ARGL+Y
Sbjct: 246 DGSVDDVLDKLKHLSQTLPESEQFNLGVSELETVITGVRNLGVPDKRFCIDLAIARGLNY 305
Query: 331 YTGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIF 390
YTG +YE L+ A +GS+ +GGRY+ LVG F G K+P VG+SIG+ R+
Sbjct: 306 YTGTVYETTLIGHEA--------LGSICSGGRYEELVGTF--IGEKMPGVGISIGLTRLI 355
Query: 391 SIVEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLN 450
S + + + + T QV+V + Q +L+ LK+ +L AG+ ++K +L
Sbjct: 356 SRLLK--AGILNTLPPTPAQVVVVNMQDELMPTYLKVSQQLRQAGLNVITNFEKR-QLGK 412
Query: 451 QLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRT 502
Q Q ++ GI IIG E L+ + S E+V+V DL EEIKRR
Sbjct: 413 QFQAADKQGIRFCVIIGADEAAAQKSSLKDLQSGEQVEVALADLAEEIKRRL 464
>1QE0-A nrPDB
Length = 420
Score = 374 bits (961), Expect = e-104, Method: Composition-based stats.
Identities = 103/462 (22%), Positives = 190/462 (41%), Gaps = 58/462 (12%)
Query: 55 VLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLI 114
++K P+GT+D P + + + + + I TP+FE + G+ + ++
Sbjct: 1 MIKIPRGTQDILPEDSKKWRYIENQLDELMTFYNYKEIRTPIFESTDLFARGVGDSTDVV 60
Query: 115 ----YDLKDQGGELLSLRYDLTVPFARYLAMNKL-----TNIKRYHIAKVYRRDNPAMTR 165
Y KD+G ++LR + T R +K+ IK Y+ ++R + +
Sbjct: 61 QKEMYTFKDKGDRSITLRPEGTAAVVRSYIEHKMQGNPNQPIKLYYNGPMFRYERK--QK 118
Query: 166 GRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVND-------RRILD 218
GRYR+F Q + G +P DAE L ++ I S + + +N + +
Sbjct: 119 GRYRQFNQFGVEAIGAENP-SVDAEVLAMVMHIYQSFGLKHLKLVINSVGDMASRKEYNE 177
Query: 219 GMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVS 278
+ +F + C S D + + K V A + A RI D++ +
Sbjct: 178 ALVKHFEPVIHEFCSDCQSRLHTDPMRILDCK---VDRDKEAIKTAPRITDFLNEESK-- 232
Query: 279 LVEQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEA 338
+ + YL GI + D +L RGLDYYT +E
Sbjct: 233 ---------------------AYYEQVKAYLDDLGI--PYTEDPNLVRGLDYYTHTAFE- 268
Query: 339 VLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLE 398
+++ P G + ++ GGRY+GL+ + D LSI + E
Sbjct: 269 LMMDNPNYDG----AITTLCGGGRYNGLLELLDGPSETGIGFALSIERLLLALEEEGIEL 324
Query: 399 ALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEA 458
+EE + + + + + +KL++ L GIKA+ Y + K+ Q++ +
Sbjct: 325 DIEENL-----DLFIVTMGDQADRYAVKLLNHLRHNGIKADKDYLQR-KIKGQMKQADRL 378
Query: 459 GIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKR 500
G +IG+QEL++ I ++++T+ E + + LVE K+
Sbjct: 379 GAKFTIVIGDQELENNKIDVKNMTTGESETIELDALVEYFKK 420
>6NHI-A nrPDB
Length = 457
Score = 359 bits (920), Expect = 2e-99, Method: Composition-based stats.
Identities = 137/465 (29%), Positives = 258/465 (55%), Gaps = 50/465 (10%)
Query: 60 KGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGED-SKLIYDLK 118
KGTRD++ ++++ R+ + + + + F+ G + ++TP FE TL GKYGE+ +LI+ +
Sbjct: 15 KGTRDFTAQEVSRRKYIINTLQKNFELFGFQPLETPSFENLSTLTGKYGEEGDRLIFKIL 74
Query: 119 DQGGEL----------------------LSLRYDLTVPFARYLAMN---KLTNIKRYHIA 153
+ G +LRYDLTVPFAR++AMN KRY I
Sbjct: 75 NSGNYTDKVNENDWQNKDAKKLTSQISDKALRYDLTVPFARFVAMNHGQLTFPFKRYQIQ 134
Query: 154 KVYRRDNPAMTRGRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVND 213
V+R D P +GR+REFYQCD D+ G+ + + E +++ + L + +++N+
Sbjct: 135 PVWRADRP--QKGRFREFYQCDADVVGSE-SLWQEVELVQLYFKAFKELGV-PVAIQMNN 190
Query: 214 RRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQ 273
R+IL G+ G+++ + ++DKLDK+ + V EM EKG++ E +++ D++
Sbjct: 191 RKILSGLAEYAGITE-QLIDFTVALDKLDKIGKDGVIKEM-QEKGISNEAIEKL-DFL-F 246
Query: 274 HGGVSLVEQLLQ-DPKLSQNKQALEGLGDLKLLFEYLTLFGIDDK-ISFDLSLARGLDYY 331
H ++ +E L + + + ++G+ +L+ + GID++ + F+++LARGLDYY
Sbjct: 247 HQKINALENLQELKTRFEGVEVGIQGVTELEFVLSKAMELGIDNQDLVFNITLARGLDYY 306
Query: 332 TGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFS 391
TG I+E + + +GS+ GGRY+ L +F K +P +G+S G++R +
Sbjct: 307 TGAIFEV---------KAKGVEMGSIGGGGRYNNLTEVFGVK--NIPGIGISFGLDRTYL 355
Query: 392 IVEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQ 451
++E+ L + T + + L A+ ++ E +KL+++L + GI AEL Y + KL Q
Sbjct: 356 VMEE--LGLFPENATVKVEYLFANYGEEEAIEAMKLIAQLREKGISAEL-YPEAAKLKKQ 412
Query: 452 LQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVE 496
Y E+ IP + +G+ E+++ + ++++T+ E+ + + + ++
Sbjct: 413 FTYAEKKEIPNLVFLGKDEIENANVTIKNLTTGEQETITQSEFLK 457
>1WU7-A nrPDB
Length = 434
Score = 356 bits (912), Expect = 2e-98, Method: Composition-based stats.
Identities = 116/457 (25%), Positives = 210/457 (45%), Gaps = 49/457 (10%)
Query: 53 KFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDS- 111
+ ++ +G RD+ P M V + +F + G ID P E + K GE+
Sbjct: 3 RLQIEKIRGFRDFYPEDMDVEKFIFKTAEEAAEAFGFRRIDFPSLEYLDLYRIKSGEELL 62
Query: 112 KLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLT--NIKRYHIAKVYRRDNPAMTRGRYR 169
+ Y D+GG ++L + T R + K ++ Y KV+R + P GRYR
Sbjct: 63 QQTYSFVDKGGREVTLIPEATPSTVRMVTSRKDLQRPLRWYSFPKVWRYEEPQA--GRYR 120
Query: 170 EFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGD-FLVKVNDRRILDGMFAICGVSD 228
E YQ + DI G+ P DAE + + IL L + D + +++N R+I++ + I G++
Sbjct: 121 EHYQFNADIFGSDSPE-ADAEVIALASSILDRLGLQDIYEIRINSRKIMEEI--IGGMTS 177
Query: 229 SKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPK 288
S ++ S +D+ K+S EE +++ G+ + I D G+ + ++ K
Sbjct: 178 SDPFSVFSIIDRYHKISREEFVDQL-RSAGIGEDGVSMIADLCSGTRGIDEMARIT--GK 234
Query: 289 LSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAG 348
S+ + + DL L +G+ + + +D S+ RGL YYTG+++EA +A
Sbjct: 235 SSEEIARMAAVEDL------LASYGVKN-VRYDFSIVRGLSYYTGIVFEAYDRSGQFRA- 286
Query: 349 EEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVE-QRLEALEEKIRTT 407
+ GGRYD L + G VP VG +G I +++ + ++ EK
Sbjct: 287 --------ILGGGRYDNLASLM--SGESVPAVGFGMGDAVISLLLKRENVQIPREKKSVY 336
Query: 408 ETQV------LVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIP 461
+V ++ +KL E + + E+ + G+ A QL+Y G
Sbjct: 337 ICRVGKINSSIMNEYSRKLRERGMNVTVEIMERGLSA------------QLKYASAIGAD 384
Query: 462 LVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEI 498
I GE++L+ GV+ +R++ + + +V + +VE +
Sbjct: 385 FAVIFGERDLERGVVTIRNMYTGSQENVGLDSVVEHL 421
>2EL9-A nrPDB
Length = 431
Score = 354 bits (908), Expect = 6e-98, Method: Composition-based stats.
Identities = 103/470 (21%), Positives = 190/470 (40%), Gaps = 51/470 (10%)
Query: 46 GPD-ESKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLM 104
GP + ++ +G DY P + A+ +++ + +G I P+ E
Sbjct: 1 GPGYQDPMAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFK 60
Query: 105 GKYGEDSKLI----YDLKDQGGELLSLRYDLTVPFARYLAMNKL---TNIKRYHIAKVYR 157
GE + ++ Y +D+ G+ L+LR + T R + L + ++I ++R
Sbjct: 61 RAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFR 120
Query: 158 RDNPAMTRGRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFL-VKVNDRRI 216
+ P +GRYR+F+Q ++ G P I DAE + + +L I + + +++N
Sbjct: 121 HERP--QKGRYRQFHQLGCEVFGLQGPDI-DAELIMLTARWWRALGISEHVTLELNS--- 174
Query: 217 LDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGG 276
+ + A D+ + +KLD E+ K M
Sbjct: 175 IGSLEARANYRDALVAFLEQHKEKLD----EDCKRRMYTNP------------LRVLDSK 218
Query: 277 VSLVEQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIY 336
V+ LL D + E L + L GI + + L RGLDYY ++
Sbjct: 219 NPEVQALLNDAPALGDYLDEESREHFAGLCKLLESAGIA--YTVNQRLVRGLDYYNRTVF 276
Query: 337 EAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQR 396
E V +Q G+V AGGRYDGLV GR P VG ++G+ER+ +V
Sbjct: 277 EWVTNSLGSQ--------GTVCAGGRYDGLVEQLG--GRATPAVGFAMGLERLVLLV--- 323
Query: 397 LEALEEKIRTTET-QVLVASAQKKLLEERLKLVSELWD--AGIKAELLYKKNPKLLNQLQ 453
+A+ + + + + ++ + L L D G+K + Q
Sbjct: 324 -QAVNPEFKADPVVDIYLVASGADTQSAAMALAERLRDELPGVKL-MTNHGGGNFKKQFA 381
Query: 454 YCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTG 503
++ G + ++GE E+ +G ++ + S E+ V ++ + ++ G
Sbjct: 382 RADKWGARVAVVLGESEVANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG 431
>5E3I-A nrPDB
Length = 438
Score = 352 bits (902), Expect = 2e-97, Method: Composition-based stats.
Identities = 111/453 (24%), Positives = 198/453 (43%), Gaps = 50/453 (11%)
Query: 60 KGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLI----Y 115
KG D P Q A ++ + +G + I P+ E G+ + ++ Y
Sbjct: 16 KGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATDIVEKEMY 75
Query: 116 DLKDQGG--ELLSLRYDLTVPFARYLAMNKLT---NIKRYHIAKVYRRDNPAMTRGRYRE 170
D+G E L+LR + T R L + L + +++ ++R + P +GRYR+
Sbjct: 76 TFFDKGNPPESLTLRPEGTAGCVRALVEHNLLRGATPRVWYMGPMFRYEKP--QKGRYRQ 133
Query: 171 FYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSD-- 228
F+Q + G P I DAE + + + + + D +V++ G +D
Sbjct: 134 FHQFGVETFGVATPDI-DAELIMLTARLWKRMGV-DHMVQLE--------LNTLGETDER 183
Query: 229 SKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQD-P 287
+++R + K + +E + L RI D + +++L++ P
Sbjct: 184 TEYRNALVAFLNEHKDALDEDSQRRLTTNPL------RILD-----SKIESTQKILENAP 232
Query: 288 KLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQA 347
KL + + L + L +YLT GI K + L RGLDYY ++E +Q
Sbjct: 233 KLHDFLKE-DSLSHFQQLQDYLTAAGI--KFVINQKLVRGLDYYNKTVFEWTTTALGSQ- 288
Query: 348 GEEPLGVGSVAAGGRYDGLVGMFDPKG-RKVPCVGLSIGVERIFSIVEQRLEALEEKIRT 406
G+V AGGRYDGLVG K + VP VG ++G+ER+ ++EQ +A E +R
Sbjct: 289 -------GTVCAGGRYDGLVGQLKGKADQSVPAVGFAMGMERLLLLLEQVEQA--EIVRD 339
Query: 407 TETQVLVAS-AQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAI 465
E ++ Q K L +L +L A + + +Q++ ++AG I
Sbjct: 340 CEAFLVAEPAYQSKALVLAEQLRDQLEAANSNIRIKTGSQGSMKSQMKKADQAGAVYAII 399
Query: 466 IGEQELKDGVIKLRSVTSREEVDVRREDLVEEI 498
+GE+E + + ++ + + E+ V +LV +
Sbjct: 400 LGEREWEAQQLAVKELATAEQSQVALAELVPFL 432
>4E51-A nrPDB
Length = 467
Score = 342 bits (878), Expect = 2e-94, Method: Composition-based stats.
Identities = 109/489 (22%), Positives = 200/489 (40%), Gaps = 77/489 (15%)
Query: 41 LKAQL-GPDES---KQKF-VLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTP 95
L+AQ GP K+K L KG D P+ + E + + +G + I TP
Sbjct: 12 LEAQTQGPGSMTEQKRKLEKLTGVKGMNDILPQDAGLWEFFEATVKSLLRAYGYQNIRTP 71
Query: 96 VFELKETLMGKYGEDSKLI----YDLKDQ-GGELLSLRYDLTVPFARYLAMNKLT---NI 147
+ E GE + ++ Y D GE L+LR + T R + +
Sbjct: 72 IVEHTPLFTRGIGEVTDIVEKEMYSFVDALNGENLTLRPENTAAVVRAAIEHNMLYDGPK 131
Query: 148 KRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDF 207
+ ++I ++R + P RGRYR+F+Q + G P DAE + + + L +
Sbjct: 132 RLWYIGPMFRHERP--QRGRYRQFHQVGVEALGFAGPD-ADAEIVMMCQRLWEDLGLTGI 188
Query: 208 LVKVNDRRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRI 267
+++N G+++ + + +++ + + E + AD++
Sbjct: 189 KLEINS----------LGLAEER------AAHRVELIKYLE-------------QHADKL 219
Query: 268 GDYVQQHGGVSLVEQL-LQDPKLSQ----NKQALEGLGDL-KLLFEYLTLFGIDDKISFD 321
D Q+ + + L ++P L + + ++ LGD+ + FE L + + F
Sbjct: 220 DDDAQRRLYTNPLRVLDTKNPALQEIVRNAPKLIDFLGDVSRAHFEGLQRLLKANNVPFT 279
Query: 322 LS--LARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPC 379
++ L RGLDYY ++E V + AQ G+VAAGGRYD L+ G+
Sbjct: 280 INPRLVRGLDYYNLTVFEWVTDKLGAQ--------GTVAAGGRYDPLIEQLG--GKPTAA 329
Query: 380 VGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAE 439
G ++G+ERI ++++ E++ V V E+ + L D G+
Sbjct: 330 CGWAMGIERILELLKEEHLVPEQE----GVDVYVVHQGDAAREQAFIVAERLRDTGLDVI 385
Query: 440 LLYKKNP---KLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTS----RE---EVDV 489
L + +Q++ + +G I GE E+ +G ++ + E + V
Sbjct: 386 LHCSADGAGASFKSQMKRADASGAAFAVIFGEDEVTNGTASVKPLRGTGDDGEKSVQQSV 445
Query: 490 RREDLVEEI 498
E L E +
Sbjct: 446 PVESLTEFL 454
>1ADJ-A nrPDB
Length = 421
Score = 281 bits (718), Expect = 6e-76, Method: Composition-based stats.
Identities = 104/466 (22%), Positives = 197/466 (42%), Gaps = 73/466 (15%)
Query: 60 KGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLI----Y 115
+GT+D +++ + +++ + + GA + TP+FE + G + ++ +
Sbjct: 7 RGTKDLFGKELRMHQRIVATARKVLEAAGALELVTPIFEETQVFEKGVGAATDIVRKEMF 66
Query: 116 DLKDQGGELLSLRYDLTVPFARYLAMNKL----TNIKRYHIAKVYRRDNPAMTRGRYREF 171
+D+GG L+LR + T R + + ++ + ++R + P +GRYR+F
Sbjct: 67 TFQDRGGRSLTLRPEGTAAMVRAYLEHGMKVWPQPVRLWMAGPMFRAERP--QKGRYRQF 124
Query: 172 YQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVND--------------RRIL 217
+Q +++ G+ +P++ DAE + ++ E L L + VK++ R +L
Sbjct: 125 HQVNYEALGSENPIL-DAEAVVLLYECLKELGLRRLKVKLSSVGDPEDRARYNAYLREVL 183
Query: 218 DGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGV 277
DSK R + + LD S E ++ E G+ P + D +G+ + H
Sbjct: 184 SPHREALS-EDSKERLEENPMRILD--SKSERDQALLKELGVRP-MLDFLGEEARAH--- 236
Query: 278 SLVEQLLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYE 337
L + ++ LE L + +L RGLDYY +E
Sbjct: 237 -----------LKEVERHLERLSV---------------PYELEPALVRGLDYYVRTAFE 270
Query: 338 AVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRL 397
+ AQ+ ++ GGRYDGL + G +VP VG + GVER+ +E
Sbjct: 271 VHHEEIGAQS--------ALGGGGRYDGLSELLG--GPRVPGVGFAFGVERVALALEAEG 320
Query: 398 EALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEE 457
L E+ + + ++ + E L L ++AE K L+ +
Sbjct: 321 FGLPEEKGP---DLYLIPLTEEAVAEAFYLAEALRPR-LRAEYALAPR-KPAKGLEEALK 375
Query: 458 AGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTG 503
G +GE EL+ G + L+ + + E+V + RE++ + + G
Sbjct: 376 RGAAFAGFLGEDELRAGEVTLKRLATGEQVRLSREEVPGYLLQALG 421
>3OD1-A nrPDB
Length = 400
Score = 275 bits (704), Expect = 2e-74, Method: Composition-based stats.
Identities = 82/396 (20%), Positives = 158/396 (39%), Gaps = 33/396 (8%)
Query: 48 DESKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKY 107
+ + F+ + P G RD P ++ + D + G ++I+TP E ET+
Sbjct: 2 NAMSKPFMFEKPFGMRDTLPEWYKTKKNICDQMTEEINLWGYDMIETPTLEYYETVGVVS 61
Query: 108 GEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAM---NKLTNIKRYHIAKVYRRDNPAMT 164
+ ++ L DQ G L LR D+T P AR +A ++ ++ + + VYR
Sbjct: 62 AILDQQLFKLLDQQGNTLVLRPDMTAPIARLVASSLKDRAYPLRLAYQSNVYRAQQN--E 119
Query: 165 RGRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAIC 224
G+ EF Q ++ G+ D E + +M L + +F V + ++ +
Sbjct: 120 GGKPAEFEQLGVELIGD-GTASADGEVIALMIAALKRAGLSEFKVAIGHVGYVNALLMDV 178
Query: 225 GVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLL 284
++ + + + + + V + E V L+ R+ + + GG + +E+
Sbjct: 179 VGNEQRADRLRRFLYEKNYVGYRE----HVKSLNLSTIDKSRLMNLLSLRGGRAAIEEA- 233
Query: 285 QDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTP 344
L Q ++ L ++ L+E L +G + + FDL+L + YYTGV++E +
Sbjct: 234 --RGLIQTEKGKTALAEMTKLYEVLESYGASEYVKFDLTLVLHMSYYTGVVFEGYGNRLG 291
Query: 345 AQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKI 404
+ +GGRYD L+ F R G + ++ + + E I
Sbjct: 292 V----------PLCSGGRYDELLSKFH---RPAQATGFGVRIDLLVEALNG------EII 332
Query: 405 RTTETQVLVASAQKKLLEERLKLVSELWDAGIKAEL 440
Q + + E ++L + G L
Sbjct: 333 SNGHEQTCIL-FSNERRFEAIELARKKRANGEAVVL 367
>3RAC-A nrPDB
Length = 373
Score = 271 bits (692), Expect = 6e-73, Method: Composition-based stats.
Identities = 96/375 (25%), Positives = 169/375 (45%), Gaps = 40/375 (10%)
Query: 49 ESKQKFVLKTP---KGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMG 105
E+ + F + P G D++ R+ AV ++ + + G E + + +FE +TL+
Sbjct: 17 EAVRGFADRPPGMQDGYPDFAKRRRAVETRLLSFV----EDAGYEPVTSGLFEYVDTLLR 72
Query: 106 -KYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLA---MNKLTNIKRYHIAKVYRR-DN 160
+ E S+ L D GG+ ++LR ++T AR A T I+ + +VYRR D+
Sbjct: 73 ARSPESSRDWIRLFDGGGDAVALRPEMTPSIARMAAPRVAAGRTPIRWCYCERVYRRTDD 132
Query: 161 PA---MTRGRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRIL 217
PA G+ E Q + G + D + L+++ E ++ + + V+ R++
Sbjct: 133 PASLSWASGKAAESTQVGIERIGEEASVDVDMDVLRLLHEASAAAGVRHHRIVVSHARLV 192
Query: 218 DGMFAICGVSDSKFRTICSSVDKLDKVSWEEV------KNEMVGEKGLAPEVADRIGDYV 271
+ G+S S R + + + V + E+ K+ + L A+R
Sbjct: 193 PRLLDALGISASLSRAFLACLTSGNYVQFRELWQLHAAKDVDLLANLLTWSPAERDAAKR 252
Query: 272 QQHGGVSLVEQLLQ---DPKLSQNKQALEGLGDLKLLFEYLTLFGI-DDKISFDLSLARG 327
+ +E LL+ DP+ + + + + L L E L G+ D ++FDL+L R
Sbjct: 253 SREASDRELEALLRDAVDPRAAADVR--DAWRYLCRLAEALHDSGLASDVVTFDLALHRE 310
Query: 328 LDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVE 387
LDYYTG+++E A +A GGRYD L+ F G P VG + VE
Sbjct: 311 LDYYTGLVFEMFAPGVGA----------PIAQGGRYDELLAQF---GAGAPAVGFAFEVE 357
Query: 388 RIFSIVEQRLEALEE 402
R+ +++E + E E
Sbjct: 358 RVMAVLEAQEEGEGE 372
>1Z7M-A nrPDB
Length = 344
Score = 188 bits (477), Expect = 5e-48, Method: Composition-based stats.
Identities = 71/361 (19%), Positives = 147/361 (40%), Gaps = 43/361 (11%)
Query: 52 QKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLM-----GK 106
+K P+ + + + Q+ ++ + + F + + P FE + GK
Sbjct: 18 EKINYLLPEESAEMTLNQVKSLRQIEGRLRKLFSLKNYQEVMPPSFEYTQLYTALESNGK 77
Query: 107 YGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRY-HIAKVYRRDNPAMTR 165
K+ +K +G + ++LRYD T+P R + K + RY + K++R++ +
Sbjct: 78 TFNQEKMFQFIKHEG-QSITLRYDFTLPLVRLYSQIKDSTSARYSYFGKIFRKEKRH--K 134
Query: 166 GRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICG 225
GR E YQ ++ G + E L + +++ L + + ++ + + C
Sbjct: 135 GRSTENYQIGIELFG-ESADKSELEILSLALQVIEQLGLNKTVFEIGSAKFFQRL---CQ 190
Query: 226 VSDSKFRTICSSVDKLDKVSWEEV--KNEMVGE-KGLAPEVADRIGDYVQQHGGVSLVEQ 282
++D + + K D KN E +GL E+ ++ +S +E
Sbjct: 191 LADGSTELLTELLLKKDLSGLNAFIEKNNFSKELRGLLKEI------FITNE--LSRLEN 242
Query: 283 LLQDPKLSQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQ 342
L+ + K + + LK E L++ I DL + +DYYT ++++A
Sbjct: 243 LVTNTK---DDVLISSFDQLKEFSEKLSMI---KPIIIDLGMVPKMDYYTDLMFKAY--- 293
Query: 343 TPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEE 402
+ A +P + +GGRYD L+ F + +G ++ I +E++ +
Sbjct: 294 --SSAANQP-----ILSGGRYDQLLSNFQ---EEAFAIGFCCHMDTILKALERQELEEDN 343
Query: 403 K 403
Sbjct: 344 D 344
>2LW7-A nrPDB
Length = 170
Score = 119 bits (297), Expect = 4e-27, Method: Composition-based stats.
Identities = 108/112 (96%), Positives = 109/112 (97%)
Query: 398 EALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEE 457
+ALEEKIRTTETQVLVASAQKKLLEERLKLVSEL DAGIKAELLYKKNPKLLNQLQYCEE
Sbjct: 59 KALEEKIRTTETQVLVASAQKKLLEERLKLVSELQDAGIKAELLYKKNPKLLNQLQYCEE 118
Query: 458 AGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQPLCIC 509
AGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQPL I
Sbjct: 119 AGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQPLSIS 170
Score = 94.9 bits (234), Expect = 7e-20, Method: Composition-based stats.
Identities = 59/63 (93%), Positives = 60/63 (95%)
Query: 2 AERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPKG 61
AERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK
Sbjct: 1 AERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPKA 60
Query: 62 TRD 64
+
Sbjct: 61 LEE 63
>6FUA-A nrPDB
Length = 388
Score = 116 bits (290), Expect = 2e-26, Method: Composition-based stats.
Identities = 74/388 (19%), Positives = 144/388 (37%), Gaps = 36/388 (9%)
Query: 59 PKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKE-TLMGKYGEDSKLIYDL 117
P G D +E + + + HG +++ P+ E E L G + + + +
Sbjct: 4 PDGVADVLFEDAHKQEVLRHQLTQQLITHGYQLVSPPMIEFTESLLSGASEDLKRQTFKI 63
Query: 118 KDQ-GGELLSLRYDLTVPFARYLAMNKLTNIKRY-HIAKVYRRDNPAMTRGRYREFYQCD 175
DQ G L+ +R D+T R A + I RY + V P+ G R Q
Sbjct: 64 IDQLTGRLMGIRADITPQILRIDAHHGGDGIARYCYAGDVI-HTLPSGLFG-SRTPLQLG 121
Query: 176 FDIAGNFDPMIPDAECLKIMCEILSSLQIGDFL-VKVNDRRILDGMFAICGVSDSKFRTI 234
+I G + D E + ++ +++SL + L V + I + + +S S +
Sbjct: 122 AEIFGCE-SIAADIELIDVLFSMINSLDMSAVLHVDLGHVTIFKRLAELAALSASDTEQL 180
Query: 235 CSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQ--DPKLSQN 292
+ + E +V D+ + LL Q+
Sbjct: 181 MQLYANKN-----------LPELKQVCQVLPMGSDFYTLARFGHDIANLLGRLSENAQQD 229
Query: 293 KQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPL 352
+ + + +L+ L +L +S D++ G Y+TG+++ +
Sbjct: 230 TKIVTAIDELQRLKAHLQ-VQWQCAVSIDVTELSGYHYHTGIVFNGYINS---------- 278
Query: 353 GVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVL 412
+ GGR+DG+ + G S+ V R+ + +L+A + +
Sbjct: 279 ETQPLVRGGRFDGMKSNQLATNQPRQATGFSMDVSRLLA--HTQLDAPFIVLIDYDAFNN 336
Query: 413 VASAQKKLLEERLKLVSELWDAGIKAEL 440
+ SAQ++LL L+ V+ L G + +
Sbjct: 337 LDSAQRQLL---LQQVASLRQQGYRVTM 361
>1X59-A nrPDB
Length = 73
Score = 98.3 bits (243), Expect = 7e-21, Method: Composition-based stats.
Identities = 60/60 (100%), Positives = 60/60 (100%)
Query: 1 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK 60
MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK
Sbjct: 8 MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK 67
>2I4O-A nrPDB
Length = 458
Score = 67.5 bits (163), Expect = 1e-11, Method: Composition-based stats.
Identities = 71/492 (14%), Positives = 139/492 (28%), Gaps = 79/492 (16%)
Query: 21 LKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPKGTRDYSPRQMAVREKVFDVI 80
LK+ AE++ L L+A + + G + P V +K+ ++
Sbjct: 31 LKENPKEAEIVSHR----LMLRA---------GMLRQEAAGIYAWLPLGHRVLKKIEQIV 77
Query: 81 IRCFKRHGAEVIDTPVFELKETLM--GKYGEDSKLIYDLKDQGGELLSLRY---DLTVPF 135
R GA + P +L + G+Y + + D+ L ++
Sbjct: 78 REEQNRAGAIELLMPTLQLADLWRESGRYDAYGPEMLRIADRHKRELLYGPTNEEMITEI 137
Query: 136 ARYLAMN-KLTNIKRYHIAKVYRRD-NPAMTRGRYREF-----YQCDFDIAGNFDPMIPD 188
R + K + YHI +R + P R REF Y D D AG
Sbjct: 138 FRAYIKSYKSLPLNLYHIQWKFRDEQRPRFGVMRGREFLMKDAYSFDVDEAGARKSYN-- 195
Query: 189 AECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEE 248
+ + + + + + + + + +
Sbjct: 196 -KMFVAYLRTFARMGL----------KAIPMRAETGPIGGDLSHEFIVLAETGESGVY-- 242
Query: 249 VKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLGDLKLLFEY 308
+ V + E D GD + V +D + + + + + L
Sbjct: 243 -IDRDVLNLPVPDENVDYDGDLTPIIKQWTSVYAATED--VHEPARYESEVPEANRLNTR 299
Query: 309 LTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVG 368
G +Y G A + GG Y
Sbjct: 300 GIEVGQI--------------FYFGT---KYSDSMKANVTGPDGTDAPI-HGGSY----- 336
Query: 369 MFDPKGRKVPCVGLSIGVERIFSIVEQRLEAL-EEKIRTTETQVLVASAQKKLLEERL-K 426
VG+S + I + E + +L + +
Sbjct: 337 ----------GVGVSRLLGAIIEACHDDNGIIWPEAVAPFRVTILNLKQGDAATDAACDQ 386
Query: 427 LVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREE 486
L EL G+ L + + + + GIP +G + L +G ++L+ +
Sbjct: 387 LYRELSAKGVDV-LYDDTDQRAGAKFATADLIGIPWQIHVGPRGLAEGKVELKRRSDGAR 445
Query: 487 VDVRREDLVEEI 498
++ D+V +
Sbjct: 446 ENLALADVVARL 457
>1NYR-A nrPDB
Length = 645
Score = 65.6 bits (158), Expect = 4e-11, Method: Composition-based stats.
Identities = 63/445 (14%), Positives = 144/445 (32%), Gaps = 84/445 (18%)
Query: 61 GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKY---GEDSKLIYDL 117
G + P +R ++ I+ G + + TPV + + +
Sbjct: 262 GLPLWLPNGATIRREIERYIVDKEVSMGYDHVYTPVLANVDLYKTSGHWDHYQEDMFPPM 321
Query: 118 KDQGGELLSLRYDLTVPFARYLA----MNKLTNIKRYHIAKVYRRDNPAMTRG--RYREF 171
+ E + LR A + I+ + ++R + G R R
Sbjct: 322 QLDETESMVLRPMNCPHHMMIYANKPHSYRELPIRIAELGTMHRYEASGAVSGLQRVRGM 381
Query: 172 YQCDFDIAGNFDPMIPDAE-CLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSK 230
D I D + + + + ++ ++ D+ +++ R
Sbjct: 382 TLNDSHIFVRPDQIKEEFKRVVNMIIDVYKDFGFEDYSFRLSYR---------------- 425
Query: 231 FRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLS 290
D DK + + + + + E AD +G + + E PKL
Sbjct: 426 --------DPEDKEKYFDDDDMWNKAENMLKEAADELG--LSYEEAIG--EAAFYGPKL- 472
Query: 291 QNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEE 350
+ Q +G + L F + ++ FDL+ Y G Q GE
Sbjct: 473 -DVQVKTAMGKEETLSTAQLDFLLPER--FDLT-------YIG------------QDGEH 510
Query: 351 PLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQ 410
V V G+ +ER + + + + +
Sbjct: 511 HRPV----------------------VIHRGVVSTMERFVAFLTEETKGAFPTWLAPKQV 548
Query: 411 VLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQE 470
++ + +L EL G++ + +N K+ +++ + IP ++G++E
Sbjct: 549 QIIPVNVDLHYDYARQLQDELKSQGVRVSID-DRNEKMGYKIREAQMQKIPYQIVVGDKE 607
Query: 471 LKDGVIKLRSVTSREEVDVRREDLV 495
+++ + +R S+++ V +++ +
Sbjct: 608 VENNQVNVRQYGSQDQETVEKDEFI 632
>1USY-C nrPDB
Length = 275
Score = 54.4 bits (129), Expect = 1e-07, Method: Composition-based stats.
Identities = 57/294 (19%), Positives = 98/294 (33%), Gaps = 48/294 (16%)
Query: 74 EKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQGGELLSLRYDLTV 133
EKVF + K+ G P E E G D+ G L S+R D T
Sbjct: 7 EKVFSFYSKATKK-GFSPFFVPALEKAEEPAGN---------FFLDRKGNLFSIREDFTK 56
Query: 134 PFARYLAMNKLT----NIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGNFDPMIPDA 189
L K IK ++ VYR + YQ + + +
Sbjct: 57 TV---LNHRKRYSPESQIKVWYADFVYRYSGSDLVA-----EYQLGLEKV-PRNSLDDSL 107
Query: 190 ECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEV 249
E L+I+ E S G +V++ + + + + + + +D + E
Sbjct: 108 EVLEIIVESASEFFEGPVIVEIGHTGLYEDLLK--EIPKDLHEKVLNLIDTKNLAEIE-- 163
Query: 250 KNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLGDLKLLFEYL 309
+ K + ++I + ++ + D LS + L L+ F +
Sbjct: 164 --FLSHMKKIDLSRVEKIIEDSIYRRSPEHLKTM--DLPLSVREDLLSASSFLQEKFPTV 219
Query: 310 TLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRY 363
+ + DL+LAR ++ Y G+I+ VAAGG Y
Sbjct: 220 S-------VEIDLTLARTIEEYCGLIFTIYDTS----------SSRLVAAGGEY 256
>1NJ8-A nrPDB
Length = 459
Score = 47.1 bits (110), Expect = 2e-05, Method: Composition-based stats.
Identities = 31/164 (18%), Positives = 56/164 (34%), Gaps = 23/164 (14%)
Query: 60 KGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKD 119
KG Y P +R F++I G + P+ ++ L +++ I +D
Sbjct: 28 KGCGVYLPYGFKIRRYTFEIIRNLLDESGHDEALFPMLIPEDLLAK----EAEHIKGFED 83
Query: 120 Q------GGEL-----LSLRYDLTVPFARY----LAMNKLTNIKRYHIAKVYRRDNPAMT 164
+ GG+ L+LR P + ++ IK Y I +R +
Sbjct: 84 EVYWVTHGGKTQLDVKLALRPTSETPIYYMMKLWVKVHTDLPIKIYQIVNTFRYETKHTR 143
Query: 165 RG-RYRE---FYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQI 204
R RE F + + + E + I + +L I
Sbjct: 144 PLIRLREIMTFKEAHTAHSTKEEAENQVKEAISIYKKFFDTLGI 187
>6JP2-A nrPDB
Length = 278
Score = 46.7 bits (109), Expect = 2e-05, Method: Composition-based stats.
Identities = 37/237 (15%), Positives = 79/237 (33%), Gaps = 23/237 (9%)
Query: 14 QGERVR----GLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPKGTRDYSPRQ 69
Q +R+R G +QK +L + A ++ +E K K ++ P
Sbjct: 12 QIQRLREYGNGTYEQKVFEDLASRDAAFSKEMSVASTDNEKKIKGMIANPS--------- 62
Query: 70 MAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQGGELLSLRY 129
++ + I G + TP+F K+ L + K ++ E +LR
Sbjct: 63 RHGLTQLMNDIADALVAEGFIEVRTPIFISKDALARMTITEDKPLFKQVFWIDEKRALRP 122
Query: 130 DLTV---PFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGNFDPMI 186
L R L + +K + + +R+++ + EF + G
Sbjct: 123 MLAPNLYSVMRDLRDHTDGPVKIFEMGSCFRKESHSGMH--LEEFTMLNLVDMGPRGDAT 180
Query: 187 PDAECLKIMCE-ILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKLD 242
E LK ++ + + D+ + + + ++ + + LD
Sbjct: 181 ---EVLKNYISVVMKAAGLPDYDLVQEESDVYKETID-VEINGQEVCSAAVGPHYLD 233
>3A31-A nrPDB
Length = 471
Score = 46.7 bits (109), Expect = 2e-05, Method: Composition-based stats.
Identities = 61/360 (16%), Positives = 114/360 (31%), Gaps = 38/360 (10%)
Query: 40 KLKAQLGPDESK----QKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTP 95
+L + PD ++F T G +S +R + +V+ + R G V++TP
Sbjct: 15 ELDITVKPDSRVPVFNREFATFTGAGVPLFSLGGGPIRYALAEVLAKFHARRGYYVVETP 74
Query: 96 VFELKETLMGKYGED--SKLIYDLKDQGGELLSLRYDLTVP----FARYLAMNKL---TN 146
+ E + +Y L D G +++ F +A ++
Sbjct: 75 IIASTELFKVSGHIEFYRNNMY-LFDIEGHEFAVKPMNCPYHILLFLNEVAKHRSKLPLP 133
Query: 147 IKRYHIAKVYRRDNPAMTRG--RYREFYQCDFDIA---GNFDPMIPDA-ECLKIMCEILS 200
K + +V+R + G R R F Q D I G ++ D E +K++ E L
Sbjct: 134 FKVFEFGRVHRYEPSGSIYGLLRVRGFTQDDAHIIVPGGRVIDVVYDVFEEMKLVLERLF 193
Query: 201 SLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLA 260
L + KV +SD K + EE E
Sbjct: 194 KLGVSSETFKV-----------RLSMSDKSLIGKEFMGSKEEWEGAEEALREAASRINEK 242
Query: 261 --PEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGL-----GDLKLLFEYLTLFG 313
++ + G+ + + + + + + +L FG
Sbjct: 243 YGIDIVELEGEAAFYGPKLDFIMMVEESGVSKEWQMGTIQFDFNLPRRFRLYDVVREEFG 302
Query: 314 IDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPK 373
I++ +L ++ + GV E + P V +V GG D +
Sbjct: 303 IEEVYIIHRALLGSIERFLGVYLEHRRGRMPFTLAPIQFAVIAVKTGGEVDREIEDLASS 362
>6NAB-A nrPDB
Length = 513
Score = 44.0 bits (102), Expect = 2e-04, Method: Composition-based stats.
Identities = 24/161 (14%), Positives = 49/161 (30%), Gaps = 22/161 (13%)
Query: 60 KGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDL-- 117
G + P V E V K+ G + + P+F + +
Sbjct: 42 SGCYIFRPNCWFVWESVQKFFDAEIKKLGVQNVMFPLF----VTKRALETEKDHVEGFSP 97
Query: 118 ----KDQGGEL-----LSLRYD----LTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMT 164
+ G ++LR + +A+++ ++ +K V R +
Sbjct: 98 EVAWVTKSGNSDLQEPIALRPTSETIMYPSYAKWIQSHRDLPLKLNQWTNVVRWEFKHAV 157
Query: 165 RG-RYREFY-QCDFDIAGNFDPMIPDA-ECLKIMCEILSSL 202
R REFY Q + + + L++ + L
Sbjct: 158 PFIRSREFYWQEGHSAFKSKEEADEEVFTILELYKRVYEEL 198
Score = 40.6 bits (93), Expect = 0.002, Method: Composition-based stats.
Identities = 26/120 (21%), Positives = 49/120 (40%), Gaps = 6/120 (5%)
Query: 381 GLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASA------QKKLLEERLKLVSELWDA 434
GLS + +V + + R QV+V L+E+ ++ +EL A
Sbjct: 270 GLSTRTLGVMIMVHGDDKGMVLPPRVAFCQVVVIPLIFKDKDNATLVEKTKEIYNELEKA 329
Query: 435 GIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDL 494
GI+ +L + + Y E G+PL +G ++L+ I L + E+ + +
Sbjct: 330 GIRVKLDDRLERTPGWKYNYWELRGVPLRIEVGPKDLEKQQIMLCRRDTGEKWTMPLSEF 389
>5Z5E-A nrPDB
Length = 534
Score = 43.3 bits (100), Expect = 2e-04, Method: Composition-based stats.
Identities = 27/136 (19%), Positives = 57/136 (41%), Gaps = 19/136 (13%)
Query: 382 LSIGVER-----IFSIVEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGI 436
LS GV+R I + + +E + + + +V K L ++ + L +
Sbjct: 394 LSFGVDRNVLALIDLFLTEEEYEIERDNQKVKEKRVVLKIPKHLAPIKVAVFPLLKKPEL 453
Query: 437 --KAE------------LLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVT 482
KA+ ++Y + + + + +E G+P I Q L+D + +R
Sbjct: 454 IEKAKEVYNMLKNYFYPIIYDEQGSIGRRYRRVDEIGVPYAITIDYQTLEDNTVTIRDRD 513
Query: 483 SREEVDVRREDLVEEI 498
+ ++V V+ EDL ++
Sbjct: 514 TMKQVRVKIEDLPNQL 529
>4K87-A nrPDB
Length = 535
Score = 43.3 bits (100), Expect = 2e-04, Method: Composition-based stats.
Identities = 27/157 (17%), Positives = 54/157 (34%), Gaps = 14/157 (8%)
Query: 60 KGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGK-------YGEDSK 112
G P A+ E + D K+ G E P+F + L + E +
Sbjct: 67 SGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAW 126
Query: 113 LIYDLKDQGGELLSLRYD----LTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRG-R 167
+ K + E +++R + +A+++ ++ IK V R + R
Sbjct: 127 VTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLR 186
Query: 168 YREF-YQCDFDIAGNFDPMIPDA-ECLKIMCEILSSL 202
REF +Q + + + L + ++ L
Sbjct: 187 TREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEEL 223
>6MN8-A nrPDB
Length = 505
Score = 41.7 bits (96), Expect = 8e-04, Method: Composition-based stats.
Identities = 19/88 (21%), Positives = 41/88 (46%)
Query: 415 SAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDG 474
+ L+E+ ++ ++L DA I+AEL + + + + E G+P+ IG ++L +
Sbjct: 310 EQKTALIEKAKEINNKLMDASIRAELDIRDHISPGWKFNHWELKGVPVRIEIGPKDLANN 369
Query: 475 VIKLRSVTSREEVDVRREDLVEEIKRRT 502
+ S E+ + + L + K
Sbjct: 370 QVTCVIRYSGEKRTIPIDGLASKCKDML 397
Score = 38.6 bits (88), Expect = 0.007, Method: Composition-based stats.
Identities = 27/157 (17%), Positives = 54/157 (34%), Gaps = 14/157 (8%)
Query: 60 KGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLI--YDL 117
G P A+ E + + K+ G + P+F + L + S
Sbjct: 37 SGCYVLRPWSYAIWEFIQEWFDEEIKKLGVKNCYFPLFVSQSALEKEKTHISDFAPEVAW 96
Query: 118 KDQGGEL-----LSLRYD----LTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRG-R 167
+ G+ +++R + +A+++ ++ IK V R + T R
Sbjct: 97 ITRAGQSDLAEAIAIRPTSETVMYPSYAKWVQSHRDLPIKLNQWCNVVRWEFKHPTPFLR 156
Query: 168 YREF-YQCDFDIAGNFDPMIPDA-ECLKIMCEILSSL 202
REF +Q + D + + L + +I L
Sbjct: 157 TREFLWQEGHTAFQSKDEAEDEVFKILDLYAQIYIDL 193
>1B76-A nrPDB
Length = 442
Score = 41.0 bits (94), Expect = 0.001, Method: Composition-based stats.
Identities = 20/130 (15%), Positives = 54/130 (41%), Gaps = 11/130 (8%)
Query: 383 SIGVERIFSIVEQRLEALEEKIRTTETQVL-VASAQKKLLEERLKLVSELWDAGIKAELL 441
+ E + + E+ + L+ ++ + V+ + + ++ E +L + L G+ +L
Sbjct: 312 AFTREELPNGEERIVLKLKPQLAPIKVAVIPLVKNRPEITEYAKRLKARLLALGLG-RVL 370
Query: 442 YKKNPKLLNQLQYCEEAGIPLVAIIGEQEL---KDGV------IKLRSVTSREEVDVRRE 492
Y+ + + +E G P + + KDG + +R + E++ + +
Sbjct: 371 YEDTGNIGKAYRRHDEVGTPFAVTVDYDTIGQSKDGTTRLKDTVTVRDRDTMEQIRLHVD 430
Query: 493 DLVEEIKRRT 502
+L ++ R
Sbjct: 431 ELEGFLRERL 440
>1NJ2-A nrPDB
Length = 501
Score = 41.0 bits (94), Expect = 0.001, Method: Composition-based stats.
Identities = 25/129 (19%), Positives = 50/129 (38%), Gaps = 6/129 (4%)
Query: 379 CVGLSIGVERIFSIVEQRLEAL--EEKIR---TTETQVLVASAQKKLLEERLKLVSELWD 433
C GLS V + L + ++ A ++++E +L S L
Sbjct: 285 CYGLSDRVIASVIAIHGDESGLCLPPDVAAHQVVIVPIIFKKAAEEVMEACRELRSRLEA 344
Query: 434 AGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRRED 493
AG + L ++ + + E G+PL IG ++L+ G + + E+V +
Sbjct: 345 AGFRVHLD-DRDIRAGRKYYEWEMRGVPLRVEIGPRDLEKGAAVISRRDTGEKVTADLQG 403
Query: 494 LVEEIKRRT 502
+ E ++
Sbjct: 404 IEETLRELM 412
>5W25-A nrPDB
Length = 616
Score = 40.6 bits (93), Expect = 0.002, Method: Composition-based stats.
Identities = 39/242 (16%), Positives = 69/242 (28%), Gaps = 42/242 (17%)
Query: 63 RDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIY---DLKD 119
RD + +R +V RH I+TP T+ E ++ L
Sbjct: 155 RDDPAAAIRLRSRVNAAARAVLARHDFVEIETP------TITRSTPEGARDFLVPARLHP 208
Query: 120 QGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIA 179
L L M + I R + + +R D EF Q D ++
Sbjct: 209 GSFYALPQSPQLFKQLLMVAGMERYYQIARCYRDEDFRADRQP-------EFTQLDMEM- 260
Query: 180 GNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVD 239
DAE + + +L ++A+ G +
Sbjct: 261 -----SFVDAEDIIAI-----------------SEEVLTELWALIGYRIPTPIPRIGYAE 298
Query: 240 KLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGL 299
+ + ++ E E D D + V ++ SQ ++ L+G
Sbjct: 299 AMRRFGTDKPDLRFGLEL---VECTDFFSDTTFRVFQAPYVGAVVMPGGASQPRRTLDGW 355
Query: 300 GD 301
D
Sbjct: 356 QD 357
>1ATI-A nrPDB
Length = 505
Score = 40.6 bits (93), Expect = 0.002, Method: Composition-based stats.
Identities = 20/130 (15%), Positives = 54/130 (41%), Gaps = 11/130 (8%)
Query: 383 SIGVERIFSIVEQRLEALEEKIRTTETQVL-VASAQKKLLEERLKLVSELWDAGIKAELL 441
+ E + + E+ + L+ ++ + V+ + + ++ E +L + L G+ +L
Sbjct: 375 AFTREELPNGEERIVLKLKPQLAPIKVAVIPLVKNRPEITEYAKRLKARLLALGLG-RVL 433
Query: 442 YKKNPKLLNQLQYCEEAGIPLVAIIGEQEL---KDGV------IKLRSVTSREEVDVRRE 492
Y+ + + +E G P + + KDG + +R + E++ + +
Sbjct: 434 YEDTGNIGKAYRRHDEVGTPFAVTVDYDTIGQSKDGTTRLKDTVTVRDRDTMEQIRLHVD 493
Query: 493 DLVEEIKRRT 502
+L ++ R
Sbjct: 494 ELEGFLRERL 503
>4P3N-A nrPDB
Length = 415
Score = 40.2 bits (92), Expect = 0.002, Method: Composition-based stats.
Identities = 36/236 (15%), Positives = 83/236 (35%), Gaps = 14/236 (5%)
Query: 44 QLGPDESKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETL 103
++G D+ F +P + P+ + + + I +++ G + + TP
Sbjct: 17 KIGRDQELYFFHELSPGSCF-FLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRLW 75
Query: 104 M--GKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMN----KLTNIKRYHIAKVYR 157
M G + S+ ++ + + EL +L+ + ++ ++R
Sbjct: 76 MTSGHWQHYSENMFSFEVE-KELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHR 134
Query: 158 RDNPAMTRG--RYREFYQCDFDIAGNFDPMIPDAE-CLKIMCEILSSLQIGDFLVKVNDR 214
+ G R R F Q D I + + + + CL + + S F K+N
Sbjct: 135 NELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFG---FSFKLNLS 191
Query: 215 RILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDY 270
+ V D + + +S+++ + + + ++ D IG Y
Sbjct: 192 TRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRY 247
>3WRZ-A nrPDB
Length = 367
Score = 39.8 bits (91), Expect = 0.003, Method: Composition-based stats.
Identities = 51/304 (16%), Positives = 92/304 (30%), Gaps = 47/304 (15%)
Query: 25 KASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPKGT-----------------RDYSP 67
+ + E+++ VA L+ +AQ P L P+GT D
Sbjct: 7 RQTREVLDPIVASLM--EAQQIPG---MAIALVRPEGTTISHYGAADRETGTPVDDDTLF 61
Query: 68 RQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQGGELLSL 127
++ + + + + G D PV L G +D + GG L
Sbjct: 62 EIGSLSKTLTATLASLAEVEGKLDFDAPVSRYLPELEGSAFDDISGLNLGTHTGGGLPLF 121
Query: 128 RYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGNFDPMIP 187
D ++ + + Y R P G R + + G
Sbjct: 122 VPDE--------VTDRASLMAWY------REWQPTEPIGESRTYSNLGIGLLGLETAASL 167
Query: 188 DAE-CLKIMCEILSSLQIGDFLVKVNDRRIL----------DGMFAICGVSDSKFRTICS 236
D E + ++L+ L + D V + R+ GV D + I +
Sbjct: 168 DGEFVPTMRAKVLAPLGMQDTWYDVPEARMADYAMGEDKDGQPTRVSPGVLDDEAYGIKT 227
Query: 237 SVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQAL 296
+ L K+ + V + A R G Y +L+ + P + +A
Sbjct: 228 TAADLAKLVRANLHLADVDAELQQAIDATRQGHYRVGDMTQALIWEQYSLPVAPETLRAG 287
Query: 297 EGLG 300
+G
Sbjct: 288 QGYD 291
>3VQX-A nrPDB
Length = 291
Score = 39.0 bits (89), Expect = 0.005, Method: Composition-based stats.
Identities = 24/137 (17%), Positives = 46/137 (33%), Gaps = 6/137 (4%)
Query: 49 ESKQKFVLKTPKGTRDYSPRQMAVRE-KVFDVIIRCFKRHGAEVIDTPVFELKETLMGKY 107
E + + + + K + + K+ I R F G I +P+ E +
Sbjct: 55 ELESELLSRRKKDLQQIYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMG 114
Query: 108 GEDSKLIYDLKDQGGELLSLRYDLTVPF---ARYLAMNKLTNIKRYHIAKVYRRDNPAMT 164
++ + + + LR L R L IK + I YR++ +
Sbjct: 115 IDNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPDPIKIFEIGPCYRKE--SDG 172
Query: 165 RGRYREFYQCDFDIAGN 181
+ EF +F G+
Sbjct: 173 KEHLEEFTMLNFCQMGS 189
>1IL2-A nrPDB
Length = 590
Score = 37.9 bits (86), Expect = 0.010, Method: Composition-based stats.
Identities = 30/147 (20%), Positives = 57/147 (38%), Gaps = 14/147 (9%)
Query: 66 SPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQGGELL 125
+++ R K+ ++ R HG I+TP+ T G L+ +G +
Sbjct: 134 MAQRLKTRAKITSLVRRFMDDHGFLDIETPML----TKATPEGARDYLVPSRVHKG-KFY 188
Query: 126 SLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGNFDPM 185
+L F + L M+ + Y I K +R ++ R EF Q D + + P
Sbjct: 189 AL-PQSPQLFKQLLMMSGFD--RYYQIVKCFRDEDLRAD--RQPEFTQIDVETSFMTAPQ 243
Query: 186 IPDAECLKIMCEIL---SSLQIGDFLV 209
+ + ++ + + +GDF V
Sbjct: 244 VREV-MEALVRHLWLEVKGVDLGDFPV 269
>5XIL-A nrPDB
Length = 512
Score = 37.9 bits (86), Expect = 0.012, Method: Composition-based stats.
Identities = 27/123 (21%), Positives = 49/123 (39%), Gaps = 10/123 (8%)
Query: 381 GLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQ------KKLLEERL----KLVSE 430
GLS V + +V + R TQV++ ++ +E L +L SE
Sbjct: 263 GLSTRVIGVMIMVHGDNRGMVMPPRVASTQVIIIPVGITKDTTEEARQELLASCWRLESE 322
Query: 431 LWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVR 490
L + G++A + N + + E G+PL +G +EL + + + S V
Sbjct: 323 LCEGGVRARCDLRDNYSPGWRFNHWEVKGVPLRVELGPRELAERSLAVAVRHSGARHSVA 382
Query: 491 RED 493
+
Sbjct: 383 WDA 385
>4WJ3-M nrPDB
Length = 599
Score = 36.7 bits (83), Expect = 0.022, Method: Composition-based stats.
Identities = 46/249 (18%), Positives = 89/249 (35%), Gaps = 25/249 (10%)
Query: 11 VKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPKGTR--DYSPR 68
V+L+ E R S E++ E+ L + + P + +T R D
Sbjct: 84 VRLRPEGARNPNMASGSIEVLGYELEVLNQAETPPFPLDEYSDVGEETRLRYRFIDLRRP 143
Query: 69 QMA----VREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKL-IYDLKDQGGE 123
+MA +R ++ I R +G ++TP+ L E ++ + + G
Sbjct: 144 EMAAKLKLRARITSSIRRYLDDNGFLDVETPI------LGRPTPEGARDYLVPSRTYPGH 197
Query: 124 LLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGNFD 183
+L + + L M + + Y IAK +R ++ R EF Q D +
Sbjct: 198 FFAL--PQSPQLFKQLLMVAGFD-RYYQIAKCFRDEDLRAD--RQPEFTQIDIE-----T 247
Query: 184 PMIPDAECLKIMCEILSSL--QIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKL 241
+ +++ + I +++ L ++ D + G R VD
Sbjct: 248 SFLDESDIIGITEKMVRQLFKEVLDVEFDEFPHMPFEEAMRRYGSDKPDLRIPLELVDVA 307
Query: 242 DKVSWEEVK 250
D++ E K
Sbjct: 308 DQLKEVEFK 316
>4RMF-A nrPDB
Length = 609
Score = 36.7 bits (83), Expect = 0.025, Method: Composition-based stats.
Identities = 25/143 (17%), Positives = 45/143 (31%), Gaps = 21/143 (14%)
Query: 63 RDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIY---DLKD 119
R+ + +R KV H I+TP TL E ++ L+
Sbjct: 130 REGPGNALRLRSKVNAAARSVLAEHDFVEIETP------TLTRSTPEGARDFLVPARLQP 183
Query: 120 QGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIA 179
L L M + I R + + +R D EF Q D ++
Sbjct: 184 GSFYALPQSPQLFKQLLMVAGMERYYQIARCYRDEDFRADRQP-------EFTQLDMEM- 235
Query: 180 GNFDPMIPDAECLKIMCEILSSL 202
+ + + I ++L ++
Sbjct: 236 ----SFVEADDVIAISEQVLKAV 254
>2ZNJ-A nrPDB
Length = 308
Score = 36.3 bits (82), Expect = 0.029, Method: Composition-based stats.
Identities = 22/142 (15%), Positives = 45/142 (31%), Gaps = 8/142 (5%)
Query: 76 VFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQGGELLSLRYDLTVPF 135
+ + + + + G + TP K L + ++ LR L
Sbjct: 96 LEEKLAKALHQQGFVQVVTPTIITKSALAKMTIGEDHPLFSQVFWLDGKKCLRPMLAPNL 155
Query: 136 A---RYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGNFDPMIPDAECL 192
R L I+ + I YR+++ EF + G P+ + L
Sbjct: 156 YTLWRELERLWDKPIRIFEIGTCYRKESQGAQH--LNEFTMLNLTELG--TPLEERHQRL 211
Query: 193 K-IMCEILSSLQIGDFLVKVND 213
+ + +L + I +F +
Sbjct: 212 EDMARWVLEAAGIREFELVTES 233
>1WLE-A nrPDB
Length = 501
Score = 36.3 bits (82), Expect = 0.031, Method: Composition-based stats.
Identities = 27/148 (18%), Positives = 48/148 (32%), Gaps = 24/148 (16%)
Query: 76 VFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGED--------SKLIYDLKDQGGELLSL 127
+ + + G + P + L G E IY++ E L+L
Sbjct: 225 LVNFTLNKLIHRGFTPMTVP-----DLLRGVVFEGCGMTPNAKPSQIYNIDPSRFEDLNL 279
Query: 128 RYDLTVPFARYLAMN----KLTNIKRYHIAKVYRRDNPAMTR--GRYREFYQCDFDIAGN 181
V A Y + + I+ + YR + G YR + ++ G
Sbjct: 280 AGTAEVGLAGYFMDHSVAFRDLPIRMVCSSTCYRAETDTGKEPWGLYRVHHFTKVEMFGV 339
Query: 182 FDPMIPDA-----ECLKIMCEILSSLQI 204
P + + E L + EIL+ L +
Sbjct: 340 TGPGLEQSSELLEEFLSLQMEILTELGL 367
>2DU7-A nrPDB
Length = 549
Score = 35.6 bits (80), Expect = 0.060, Method: Composition-based stats.
Identities = 32/228 (14%), Positives = 74/228 (32%), Gaps = 47/228 (20%)
Query: 31 IEEEVAKLLKLKAQLGPDESKQKFVLKTPKGTRDYSPRQMAVREKVF------------- 77
+ E + +L + ++G +E ++ + + + P MAV ++ F
Sbjct: 59 VMETIERLRQAYLRMGFEEMINPVIVDEMEIYKQFGPEAMAVLDRCFYLAGLPRPDVGLG 118
Query: 78 DVIIRCFKRHGA---EVIDTPVFELKETLMGKYGEDSKLIYD------------------ 116
+ + K G E + E+ + L+++
Sbjct: 119 NEKVEIIKNLGIDIDEEKKERLREVLHLYKKGAIDGDDLVFEIAKALNVSNEMGLKVLET 178
Query: 117 ----LKDQGGEL--LSLRYDLTVP---FARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGR 167
KD E L+LR +T L + +K + I + +RR+ R
Sbjct: 179 AFPEFKDLKPESTTLTLRSHMTSGWFITLSSLIKKRKLPLKLFSIDRCFRREQRE-DRSH 237
Query: 168 YREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRR 215
++ + G + D + + +L+ F K ++++
Sbjct: 238 LMSYHSASCVVVGEDVSVD-DGKVVA--EGLLAQFGFTKFKFKPDEKK 282
>5XIP-A nrPDB
Length = 498
Score = 34.8 bits (78), Expect = 0.090, Method: Composition-based stats.
Identities = 28/160 (17%), Positives = 50/160 (31%), Gaps = 22/160 (13%)
Query: 60 KGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLK- 118
G P + E V KR G E P+F K ++ + K
Sbjct: 33 SGCYIIRPWAYRIWEAVQKFFDDGIKRLGVENCYFPMF----VSQAKLEKEKDHVEGFKP 88
Query: 119 ------DQGG----ELLSLRYD----LTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMT 164
G E +++R + +A+++ ++ +K V R + T
Sbjct: 89 EVAWVTHYGDSELPEKVAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWNNVVRWEFKQPT 148
Query: 165 RG-RYREF-YQCDFDI-AGNFDPMIPDAECLKIMCEILSS 201
R REF +Q A + E L++ +
Sbjct: 149 PFLRTREFLWQEGHTAHATEEEAYTLVLEILELYRQWYED 188
>2DJV-A nrPDB
Length = 79
Score = 34.8 bits (78), Expect = 0.10, Method: Composition-based stats.
Identities = 24/46 (52%), Positives = 26/46 (56%)
Query: 6 ALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESK 51
AL + V QG VR LK QKA + EVAKLL LK QL E K
Sbjct: 17 ALMDEVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAVAEGK 62
>5XIG-A nrPDB
Length = 500
Score = 34.4 bits (77), Expect = 0.12, Method: Composition-based stats.
Identities = 17/109 (15%), Positives = 45/109 (41%), Gaps = 4/109 (3%)
Query: 394 EQRLEALEEKIRTTETQVLVASAQKKLLEERL----KLVSELWDAGIKAELLYKKNPKLL 449
+ + + ++ + + ++ + + E L +L + L A I+ + + N
Sbjct: 275 DDKGLVIPPRVASVQVVIIPILFKDENTGEILGKCRELKTMLEKADIRVRIDDRSNYTPG 334
Query: 450 NQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEI 498
+ + E G+PL +G ++L G ++ + E + DL ++
Sbjct: 335 WKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKL 383
>2ODR-C nrPDB
Length = 701
Score = 32.9 bits (73), Expect = 0.37, Method: Composition-based stats.
Identities = 21/110 (19%), Positives = 39/110 (35%), Gaps = 9/110 (8%)
Query: 111 SKLIYDLKD--QGGELLSLRYDLTVP---FARYLAMNKLTNIKRYHIAKVYRRDNPAMTR 165
+ + KD L+LR +T L K K + I + +RR+ +
Sbjct: 184 EDVFPEFKDLTAVSSKLTLRSHMTSGWFLTVSDLMNKKPLPFKLFSIDRCFRREQKE-DK 242
Query: 166 GRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRR 215
++ IAG I D + I +LS +F ++++
Sbjct: 243 SHLMTYHSASCAIAG-EGVDINDGK--AIAEGLLSQFGFTNFKFIPDEKK 289
>6M7Z-A nrPDB
Length = 319
Score = 32.5 bits (72), Expect = 0.41, Method: Composition-based stats.
Identities = 37/244 (15%), Positives = 72/244 (29%), Gaps = 30/244 (12%)
Query: 90 EVIDTPVFELK--ETLMGKYGEDSKLIYDLKDQGGELLSLRYD----LTVPFARYLAMNK 143
+ P+ + + + + G + + + LLSL + R + N
Sbjct: 28 DESRNPILKRLLSGSFLRRDGSTTVNVRVPARELVRLLSLTPEQQREGVSAKVRLI--NL 85
Query: 144 LTNIKRYHIAKVYRRDNPAMTR------GRYRE------FYQCDFDIAG---NFDPMIPD 188
L + +YR P + G YR F+ + G PD
Sbjct: 86 LDPKYSVYEPYLYREILPKRSPLLLPSLGEYRGAFLTYIFHPLSKGLVGDMLETGRSHPD 145
Query: 189 AECLKI----MCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKLDKV 244
+ L + L +L + +++N +L + G D+ + +
Sbjct: 146 VQVLAANMVAALKSLHNLGLLHRSIELNSFSVLPDGTVVLGGLDTAAPIGTETRLWVGFF 205
Query: 245 SWE---EVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLGD 301
E E+ + + L D + QLL + L +
Sbjct: 206 GQETAPEIDRNFLADLALTQGRHTVKSDVYSLGVAFRNLVQLLGNGNLGPEDRGAVRQDH 265
Query: 302 LKLL 305
L+LL
Sbjct: 266 LELL 269
>1CRU-A nrPDB
Length = 454
Score = 32.5 bits (72), Expect = 0.49, Method: Composition-based stats.
Identities = 25/108 (23%), Positives = 42/108 (38%), Gaps = 12/108 (11%)
Query: 56 LKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVID----TPVFELKETLMGKYGEDS 111
K PK T P Q +R ++ + + +D P + ++ G D
Sbjct: 100 FKNPKSTDKELPNQTIIRRYTYNKSTDTLE----KPVDLLAGLPSSKDHQSGRLVIGPDQ 155
Query: 112 KLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRY--HIAKVYR 157
K+ Y + DQG L+ Y A++ + N K Y ++ KV R
Sbjct: 156 KIYYTIGDQGRNQLA--YLFLPNQAQHTPTQQELNGKDYHTYMGKVLR 201
>4NCX-A nrPDB
Length = 506
Score = 32.1 bits (71), Expect = 0.53, Method: Composition-based stats.
Identities = 20/128 (15%), Positives = 53/128 (41%), Gaps = 5/128 (3%)
Query: 379 CVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASA---QKKLLEERLKLVSE-LWDA 434
C SIG+ I + + + L + + ++ + + K + + L +A
Sbjct: 271 CTTRSIGI-MIMTHGDDKGLVLPPNVSKYKVVIVPIFYKTTDENAIHSYCKDIEKILKNA 329
Query: 435 GIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDL 494
I + + + + E GIP+ +G ++L++ + + E+ +V++E +
Sbjct: 330 QINCVYDDRASYSPGYKFNHWELRGIPIRIEVGPKDLQNNSCVIVRRDNNEKCNVKKESV 389
Query: 495 VEEIKRRT 502
+ E ++
Sbjct: 390 LLETQQML 397
>5IJN-G nrPDB
Length = 599
Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats.
Identities = 17/45 (37%), Positives = 20/45 (44%)
Query: 341 LQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIG 385
+ T G LG +VAAGG G V F P VGL+ G
Sbjct: 1 MSTGFSFGSGTLGSTTVAAGGTSTGGVFSFGTGASSNPSVGLNFG 45
>3A74-A nrPDB
Length = 493
Score = 30.6 bits (67), Expect = 1.9, Method: Composition-based stats.
Identities = 15/88 (17%), Positives = 30/88 (34%), Gaps = 8/88 (9%)
Query: 72 VREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQGGELLSLRYDL 131
R + + R HG ++TP+ G ++ + L +R +
Sbjct: 176 TRSLIIQSMRRYLDSHGYLEVETPMMH-----AVAGGAAARPFITHHNALDMTLYMRIAI 230
Query: 132 TVPFARYLAMNKLTNIKRYHIAKVYRRD 159
+ R + K Y I +V+R +
Sbjct: 231 ELHLKRLIVGGLE---KVYEIGRVFRNE 255
>5ZG8-A nrPDB
Length = 438
Score = 30.2 bits (66), Expect = 2.2, Method: Composition-based stats.
Identities = 18/96 (18%), Positives = 32/96 (33%), Gaps = 10/96 (10%)
Query: 70 MAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQGGELLSLRY 129
M +R+++ I F G D P+ L E + +++++ GE L
Sbjct: 131 MRIRDELERAIHEFFGERGFLRFDAPI------LTPSAVEGTTELFEVELFDGEKAYLSQ 184
Query: 130 DLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTR 165
+ Y L K Y +R + R
Sbjct: 185 SGQL----YAEAGALAFAKVYTFGPTFRAERSKTRR 216
>6OTE-A nrPDB
Length = 572
Score = 30.2 bits (66), Expect = 2.4, Method: Composition-based stats.
Identities = 30/152 (19%), Positives = 50/152 (32%), Gaps = 22/152 (14%)
Query: 88 GAEVIDTPVFELKETLMGKYGEDSKLIYDLKD------QG---GELLSLRYDLTVPFARY 138
G I P F ++ MGK E L +G L L P A
Sbjct: 318 GYLAIQPPYFMKRDL-MGKAAELQDFEETLYHIPSDNSKGEVDSNSLFLIATSEQPIAAM 376
Query: 139 ----LAMNKLTNIKRYHIAKVYRRDNPAMTR---GRYREFYQCD-FDIAGNFDPMIPDA- 189
+K IK I+ +R++ A + G +R +Q + + P
Sbjct: 377 HHNVTLEDKDLPIKYAGISTCFRKEAGAHGKDTWGIFR-IHQFEKVEQFCVTLPEDSQKI 435
Query: 190 --ECLKIMCEILSSLQIGDFLVKVNDRRILDG 219
E + I E SL++ ++ + + D
Sbjct: 436 HEEMISISEEFYQSLELPYRVISIVSGALNDA 467
>3MMP-A nrPDB
Length = 678
Score = 28.6 bits (62), Expect = 6.1, Method: Composition-based stats.
Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 1 MAERAALEELVK-----LQGERVRGLKQQKASAELIEEEVAKLLKLKAQLG-PDESKQKF 54
+A + A EELVK + + +K + SAE++E+E L + Q G P E +K
Sbjct: 156 VAAKGADEELVKHIAMHVAASKPEFIKPEDVSAEVVEKEYQVQLDIAMQSGKPKEIAEKM 215
Query: 55 VL 56
V
Sbjct: 216 VE 217
>5OQL-Y nrPDB
Length = 411
Score = 28.2 bits (61), Expect = 7.7, Method: Composition-based stats.
Identities = 18/106 (16%), Positives = 38/106 (35%)
Query: 325 ARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSI 384
RG+ Y TGV A G V V +YD + + + G+
Sbjct: 218 IRGVAYCTGVAASHNNRMITAARGVLNQLVSDVHIAAQYDPAPLVAEKGTTQKKKTGIGF 277
Query: 385 GVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSE 430
G+ + + + +++ E V+ +K + L ++++
Sbjct: 278 GLSLVAETSAEGVIYAADEVAPPEGGVVPEDIGEKCAYQLLDVIAQ 323
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
Posted date: Jan 3, 2023 9:05 PM
Number of letters in database: 10,336,785
Number of sequences in database: 36,641
Lambda K H
0.308 0.122 0.292
Lambda K H
0.267 0.0373 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,055,812
Number of Sequences: 36641
Number of extensions: 619348
Number of successful extensions: 2401
Number of sequences better than 10.0: 60
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 55
Number of HSP's that attempted gapping in prelim test: 2176
Number of HSP's gapped (non-prelim): 127
length of query: 509
length of database: 10,336,785
effective HSP length: 101
effective length of query: 408
effective length of database: 6,636,044
effective search space: 2707505952
effective search space used: 2707505952
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.3 bits)
S2: 61 (28.2 bits)