BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P11914 (482 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1HR7-A nrPDB 969 0.0 1HR8-B nrPDB 163 1e-40 1BCC-A nrPDB 152 3e-37 6HAW-A nrPDB 150 1e-36 3HDI-A nrPDB 150 1e-36 5XTH-AL nrPDB 140 9e-34 3L73-B nrPDB 137 1e-32 6HAW-B nrPDB 137 1e-32 5XTH-AK nrPDB 134 8e-32 5GUP-v nrPDB 132 4e-31 3L72-A nrPDB 124 7e-29 2BCC-B nrPDB 124 9e-29 3EOQ-A nrPDB 93 2e-19 6GIQ-A nrPDB 77 2e-14 5EUF-A nrPDB 67 2e-11 3CX5-B nrPDB 59 4e-09 4NNZ-A nrPDB 42 4e-04 4LIV-A nrPDB 33 0.19 2OHJ-A nrPDB 32 0.85 1Q2L-A nrPDB 31 1.0 3WV8-A nrPDB 30 2.3 1YJS-A nrPDB 29 4.0 2HQN-A nrPDB 29 5.8 3TPL-A nrPDB 28 7.2 2HQR-A nrPDB 28 7.9 >1HR7-A nrPDB Length = 475 Score = 969 bits (2505), Expect = 0.0, Method: Compositional matrix adjust. Identities = 467/469 (99%), Positives = 467/469 (99%) Query: 14 ARTDNFKLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTE 73 ARTDNFKLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTE Sbjct: 1 ARTDNFKLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTE 60 Query: 74 HVEGRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQ 133 HVEGRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQ Sbjct: 61 HVEGRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQ 120 Query: 134 EQKLSAEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNK 193 EQKLSAEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPR LIPSISKYYLLDYRNK Sbjct: 121 EQKLSAEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRGLIPSISKYYLLDYRNK 180 Query: 194 FYTPENTVAAFVGVPHEKALELTEKYLGDWQSTHPPITKKVAQYTGGESCIPPAPVFGNL 253 FYTPENTVAAFVGVPHEKALELT KYLGDWQSTHPPITKKVAQYTGGESCIPPAPVFGNL Sbjct: 181 FYTPENTVAAFVGVPHEKALELTGKYLGDWQSTHPPITKKVAQYTGGESCIPPAPVFGNL 240 Query: 254 PELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFV 313 PELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFV Sbjct: 241 PELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFV 300 Query: 314 ENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRAKNQ 373 ENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRAKNQ Sbjct: 301 ENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRAKNQ 360 Query: 374 LKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFTGNVN 433 LKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFTGNVN Sbjct: 361 LKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFTGNVN 420 Query: 434 NAGNGKGRATVVMQGDRGSFGDVENVLKAYGLGNSSSSKNDSPKKKGWF 482 NAGNGKGRATVVMQGDRGSFGDVENVLKAYGLGNSSSSKNDSPKKKGWF Sbjct: 421 NAGNGKGRATVVMQGDRGSFGDVENVLKAYGLGNSSSSKNDSPKKKGWF 469 >1HR8-B nrPDB Length = 443 Score = 163 bits (413), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 121/419 (28%), Positives = 203/419 (48%), Gaps = 37/419 (8%) Query: 20 KLSSLANGLKVATSNTPGHFSA-LGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEGR 78 + S L NGL +AT P SA +G+++DAGSR E G H L LAFK T++ + Sbjct: 8 RTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLQHLAFKGTQNRPQQ 67 Query: 79 AMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKLS 138 + +E +G + +SREN +Y A +D+ K + ++S+ + + ++ ++ Sbjct: 68 GIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERDV 127 Query: 139 AEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNKFYTPE 198 E +EV + V+ + LH Y + LG ++ P + I SI++ L DY K Y + Sbjct: 128 IIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKNYKGD 187 Query: 199 NTVAAFVG-VPHEKALELTEKYLGDWQSTHPPITKKVAQYTGGESCIP------PAPVF- 250 V A G V HEK ++ +KY G H P ES +P P PVF Sbjct: 188 RMVLAGAGAVDHEKLVQYAQKYFG-----HVP---------KSESPVPLGSPRGPLPVFC 233 Query: 251 --------GNLPELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRL 302 LP HI I EG+ PD + Q ++G A G G S L Sbjct: 234 RGERFIKENTLPTT-HIAIALEGVSWSAPDYFVALATQAIVGNWD--RAIGTGTNSPSPL 290 Query: 303 YTHVLNQYYFVENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFAN-KDLR 361 + ++F+ SY+DSG++G+ + + + V +I ++ + K + Sbjct: 291 AVAASQNGSLANSYMSFSTSYADSGLWGMYI--VTDSNEHNVRLIVNEILKEWKRIKSGK 348 Query: 362 LTEDEVSRAKNQLKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDI 420 +++ EV+RAK QLK++LL++L+ +ED+GRQV+ G+++ E+ +++ + DDI Sbjct: 349 ISDAEVNRAKAQLKAALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDI 407 >1BCC-A nrPDB Length = 446 Score = 152 bits (384), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 115/421 (27%), Positives = 205/421 (48%), Gaps = 40/421 (9%) Query: 20 KLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEGRA 79 ++S L NG++VA+ + +G++IDAGSR+E G + L+ LAFK T++ A Sbjct: 15 QVSQLDNGVRVASEQSSQPTCTVGVWIDAGSRYESEKNNGAGYFLEHLAFKGTKNRPQNA 74 Query: 80 MAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKLSA 139 + + +E +G + SSRE+ Y ++DV K ++L+++ V+ + + ++++++ Sbjct: 75 LEKEVESMGAHLNAYSSREHTAYYIKALSKDVPKAVELLADIVQNCSLEDSQIEKERDVI 134 Query: 140 EYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNKFYT-PE 198 E+ E V+ LH A+ G L + P E I +S+ L +Y + YT P Sbjct: 135 VRELQENDTSMREVVFNYLHATAFQGTGLAQSVEGPSENIRKLSRADLTEYLSTHYTAPR 194 Query: 199 NTVAAFVGVPHEKALELTEKYLGDWQSTH-----PPITKKVAQYTGG-----ESCIPPAP 248 +AA GV H++ LEL +K+ G T+ P ++K ++TG E +P Sbjct: 195 MVLAAAGGVEHQQLLELAQKHFGGVPFTYDDDAVPTLSK--CRFTGSQIRHREDGLP--- 249 Query: 249 VFGNLPELFHIQIGFEGLPIDHPDIYALATLQTLLGG-----GGSFSAGGPGKGMYSRLY 303 L H+ I EG HPD+ AL ++G GG + P + S Sbjct: 250 -------LAHVAIAVEGPGWAHPDLVALQVANAIIGHYDRTYGGGLHSSSP---LASIAV 299 Query: 304 THVLNQYYFVENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLT 363 T+ L Q + F+ YS++G+FG C + + V+ Q + ++ Sbjct: 300 TNKLCQSF-----QTFSICYSETGLFGFYFVCDRMSIDDMMFVLQGQWMRLCTS----IS 350 Query: 364 EDEVSRAKNQLKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRV 423 E EV R KN L+++L+ +L+ ED+GR++L +GR+IP+ E ++ ++ + V Sbjct: 351 ESEVLRGKNFLRNALVSHLDGTTPVCEDIGRELLTYGRRIPLEEWEERLAEVDARMVREV 410 Query: 424 A 424 Sbjct: 411 C 411 >6HAW-A nrPDB Length = 438 Score = 150 bits (379), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 111/412 (26%), Positives = 198/412 (48%), Gaps = 20/412 (4%) Query: 20 KLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEGRA 79 ++S L NGL+VA+ + +G++IDAGSR+E G + ++ LAFK T++ G A Sbjct: 14 QVSQLDNGLRVASEQSSQPTCTVGVWIDAGSRYESEKNNGAGYFVEHLAFKGTKNRPGNA 73 Query: 80 MAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKLSA 139 + + +E +G + S+RE+ Y ++D+ K ++L+++ V+ + + ++++++ Sbjct: 74 LEKEVESMGAHLNAYSTREHTAYYIKALSKDLPKAVELLADIVQNCSLEDSQIEKERDVI 133 Query: 140 EYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNKFY-TPE 198 E+ E V+ LH A+ G L + P E + +S+ L +Y ++ Y P Sbjct: 134 LQELQENDTSMRDVVFNYLHATAFQGTPLAQSVEGPSENVRKLSRADLTEYLSRHYKAPR 193 Query: 199 NTVAAFVGVPHEKALELTEKYLGDWQSTHPPITKKVAQYTGGESCIPPAPVFGNLPELFH 258 +AA G+ H + L+L +K+ P ++ ++TG + C LP L H Sbjct: 194 MVLAAAGGLEHRQLLDLAQKHFSGLSGV-PTLSP--CRFTGSQICHRE----DGLP-LAH 245 Query: 259 IQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGP--GKGMYSRLYTHVLNQYYFVENC 316 + I EG HPD AL ++G GG + S T+ L Q + Sbjct: 246 VAIAVEGPGWAHPDNVALQVANAIIGHYDCTYGGGAHLSSPLASIAATNKLCQSF----- 300 Query: 317 VAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRAKNQLKS 376 FN Y+D+G+ G C + + V+ Q + TE EV R KN L++ Sbjct: 301 QTFNICYADTGLLGAHFVCDHMSIDDMMFVLQGQWMRLCTSA----TESEVLRGKNLLRN 356 Query: 377 SLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIF 428 +L+ +L+ ED+GR +L +GR+IP+ E S+I ++ + V F Sbjct: 357 ALVSHLDGTTPVCEDIGRSLLTYGRRIPLAEWESRIAEVDARVVREVCSKYF 408 >3HDI-A nrPDB Length = 421 Score = 150 bits (379), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 110/411 (26%), Positives = 197/411 (47%), Gaps = 23/411 (5%) Query: 23 SLANGLKVATSNTPGHFS-ALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEGRAMA 81 +L NG+++ T S ++G+++ GSR+E G +H L+ + FK T + +A Sbjct: 6 TLDNGVRIITEKMSTVRSVSIGIWVGTGSRYESAEENGISHFLEHMFFKGTNTRSAQEIA 65 Query: 82 ETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKLSAEY 141 E + +GG +S+E Y A V + G+ + +S+ ++EL++++ Sbjct: 66 EFFDSIGGQVNAFTSKEYTCYYAKVLDDHAGQAIDTLSDMFFHSTFQKEELEKERKVVFE 125 Query: 142 EIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNKFYTPENTV 201 EI V P+ ++ +LL +A Y +LG P++ E + S ++ L Y ++FYT + V Sbjct: 126 EIKMVDDTPDDIVHDLLSSATYGKHSLGYPILGTVETLNSFNEGMLRHYMDRFYTGDYVV 185 Query: 202 AAFVGVPHEKALELTEKYLGDWQSTHPPITKKVAQYTGGESC-IPPAPVFGNLPELFHIQ 260 + G H+ EL +K + T + Y G + +P V E H+ Sbjct: 186 ISVAGNVHD---ELIDK----IKETFSQVKPTTYNYQGEKPMFLPNRIVRKKETEQAHLC 238 Query: 261 IGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFVENCVAFN 320 +G+ GLPI D+YAL L +LGG M SRL+ + + + +++ Sbjct: 239 LGYPGLPIGDKDVYALVLLNNVLGG-----------SMSSRLFQDIREKRGLCYSVFSYH 287 Query: 321 HSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRAKNQLKSSLLM 380 S+ DSG+ I V I Q+ + A K LTE E+ K QLK SL++ Sbjct: 288 SSFRDSGMLTIYAGTGHDQLDDLVYSI-QETTSALAEKG--LTEKELENGKEQLKGSLML 344 Query: 381 NLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFTGN 431 +LES + G+ L+ + ++EMI +I ++ D+SR+A+++ + + Sbjct: 345 SLESTNSRMSRNGKNELLLKKHRSLDEMIEQINAVQKQDVSRLAKILLSAS 395 >5XTH-AL nrPDB Length = 446 Score = 140 bits (354), Expect = 9e-34, Method: Compositional matrix adjust. Identities = 114/422 (27%), Positives = 199/422 (47%), Gaps = 41/422 (9%) Query: 20 KLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEGRA 79 ++S L NGL+VA+ + +G++ID GSRFE G + L+ LAFK T++ G A Sbjct: 15 QVSLLDNGLRVASEQSSQPTCTVGVWIDVGSRFETEKNNGAGYFLEHLAFKGTKNRPGSA 74 Query: 80 MAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKLSA 139 + + +E +G + S+RE+ Y ++D+ K ++L+ + V+ + + ++++++ Sbjct: 75 LEKEVESMGAHLNAYSTREHTAYYIKALSKDLPKAVELLGDIVQNCSLEDSQIEKERDVI 134 Query: 140 EYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNKFY-TPE 198 E+ E V+ LH A+ G L + P E + +S+ L +Y + Y P Sbjct: 135 LREMQENDASMRDVVFNYLHATAFQGTPLAQAVEGPSENVRKLSRADLTEYLSTHYKAPR 194 Query: 199 NTVAAFVGVPHEKALELTEKYLGD--WQSTHPPI-TKKVAQYTGGE-----SCIPPAPVF 250 +AA GV H++ L+L +K+LG W + T ++TG E +P A Sbjct: 195 MVLAAAGGVEHQQLLDLAQKHLGGIPWTYAEDAVPTLTPCRFTGSEIRHRDDALPFA--- 251 Query: 251 GNLPELFHIQIGFEGLPIDHPDIYALATLQTLLG------GGGSFSAGGPGKGMYSRLYT 304 H+ I EG PD AL ++G GGG + G Sbjct: 252 -------HVAIAVEGPGWASPDNVALQVANAIIGHYDCTYGGGVHLSSPLASGA------ 298 Query: 305 HVLNQYYFVENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTE 364 V N+ ++ F+ Y+++G+ G C + V+ Q + TE Sbjct: 299 -VANK--LCQSFQTFSICYAETGLLGAHFVCDRMKIDDMMFVLQGQWMRLCTSA----TE 351 Query: 365 DEVSRAKNQLKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVA 424 EV+R KN L+++L+ +L+ ED+GR +L +GR+IP+ E S+I ++ D S V Sbjct: 352 SEVARGKNILRNALVSHLDGTTPVCEDIGRSLLTYGRRIPLAEWESRIAEV---DASVVR 408 Query: 425 EM 426 E+ Sbjct: 409 EI 410 >3L73-B nrPDB Length = 441 Score = 137 bits (344), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 115/424 (27%), Positives = 193/424 (45%), Gaps = 19/424 (4%) Query: 17 DNFKLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVE 76 ++ +++ L NGL +A+ S +G++I AGSR+E G H+L + +T+ Sbjct: 24 EDLEITKLPNGLIIASLENFSPASRIGVFIKAGSRYETTANLGTAHLLRLASPLTTKGAS 83 Query: 77 GRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQK 136 + +E +GG+ S+RE + Y V +++ + P+ E+ + Sbjct: 84 SFRITRGIEAVGGSLSVYSTREKMTYCVECLRDHVDTVMEYLLNVTTAPEFRPWEVTD-- 141 Query: 137 LSAEYEIDE--VWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNKF 194 L + ++D+ + P++ + E LH AAY L +PL CP I I+ L + Sbjct: 142 LQPQLKVDKAVAFQSPQVGVLENLHAAAYK-TALANPLYCPDYRIGKITSEQLHHFVQNN 200 Query: 195 YTPENTVAAFVGVPHEKALELTEKYLGDWQSTHPPITKKVAQYTGGESCIPPAPVFGNLP 254 +T +GV H ++ E++L K A Y GGE N Sbjct: 201 FTSARMALVGIGVKHSDLKQVAEQFLNIRSGAGTSSAK--ATYWGGEIREQ------NGH 252 Query: 255 ELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFVE 314 L H + EG + + A + LQ +LG G G + S+LY V Sbjct: 253 SLVHAAVVTEGAAVGSAEANAFSVLQHVLGAGPLIK---RGSSVTSKLYQGVAKATTQPF 309 Query: 315 NCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRAKNQL 374 + AFN +YSDSG+FG I QAA A EVI M A +TE++V++AKNQL Sbjct: 310 DASAFNVNYSDSGLFG--FYTISQAA-HAGEVIRAAMNQLKAAAQGGVTEEDVTKAKNQL 366 Query: 375 KSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFTGNVNN 434 K++ LM++E+ L ++G + L+ G + + KI+ + D+ A+ +G + Sbjct: 367 KATYLMSVETAQGLLNEIGSEALLSGTHTAPSVVAQKIDSVTSADVVNAAKKFVSGKKSM 426 Query: 435 AGNG 438 A +G Sbjct: 427 AASG 430 >6HAW-B nrPDB Length = 413 Score = 137 bits (344), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 122/426 (28%), Positives = 190/426 (44%), Gaps = 30/426 (7%) Query: 18 NFKLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEG 77 + + + L NGL +A+ S +GL+I AGSR+E N G +H+L + +T+ Sbjct: 2 DLEFTRLPNGLVIASLENYAPASRIGLFIKAGSRYENSNNLGTSHLLRLASSLTTKGASS 61 Query: 78 RAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKL 137 + +E +GG TS+REN+ Y DV +++ + P+ E+ L Sbjct: 62 FKITRGIEAVGGKLSVTSTRENMAYTVECLRDDVDILMEFLLNVTTAPEFRRWEV--AAL 119 Query: 138 SAEYEIDE--VWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNKFY 195 + ID+ P+ + E LH AAY L + L CP I ++ L DY + Sbjct: 120 QPQLRIDKAVALQNPQAHVIENLHAAAYR-NALANSLYCPDYRIGKVTPVELHDYVQNHF 178 Query: 196 TPENTVAAFVGVPHEKALELTEKYLGDWQSTHPPITKKVAQYTGGESCIPPAPVFGNLPE 255 T +GV H ++ E++L A+Y GGE N Sbjct: 179 TSARMALIGLGVSHPVLKQVAEQFLNIRGGAK-------AKYHGGEIREQ------NGDS 225 Query: 256 LFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFVEN 315 L H + E I + A + LQ +LG G G S LY V + + Sbjct: 226 LVHAALVAESAAIGSAEANAFSVLQHVLGAGPHVK---RGSNATSSLYQAVAKGVHQPFD 282 Query: 316 CVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYN---TFANKDLRLTEDEVSRAKN 372 AFN SYSDSG+FG I QAA A +VI + YN T A + L+ +V AKN Sbjct: 283 VSAFNASYSDSGLFG--FYTISQAA-SAGDVI-KAAYNQVKTIAQGN--LSNPDVQAAKN 336 Query: 373 QLKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFTGNV 432 +LK+ LM++ES L+++G Q L G P + ++ +I+ + D+ A+ +G Sbjct: 337 KLKAGYLMSVESSEGFLDEVGSQALAAGSYTPPSTVLQQIDAVADADVINAAKKFVSGRK 396 Query: 433 NNAGNG 438 + A +G Sbjct: 397 SMAASG 402 >5XTH-AK nrPDB Length = 419 Score = 134 bits (337), Expect = 8e-32, Method: Compositional matrix adjust. Identities = 115/423 (27%), Positives = 188/423 (44%), Gaps = 19/423 (4%) Query: 18 NFKLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEG 77 + + + L NGL +A+ S +GL+I AGSR+E + G TH+L + +T+ Sbjct: 3 DLEFTKLPNGLVIASLENYSPVSRIGLFIKAGSRYEDFSNLGTTHLLRLTSSLTTKGASS 62 Query: 78 RAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKL 137 + +E +GG T++REN+ Y DV +++ + P+ E+ + L Sbjct: 63 FKITRGIEAVGGKLSVTATRENMAYTVECLRGDVDILMEFLLNVTTAPEFRRWEVAD--L 120 Query: 138 SAEYEIDE--VWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNKFY 195 + +ID+ + P+ + E LH AAY L +PL CP I ++ L + + Sbjct: 121 QPQLKIDKAVAFQNPQTHVIENLHAAAYR-NALANPLYCPDYRIGKVTSEELHYFVQNHF 179 Query: 196 TPENTVAAFVGVPHEKALELTEKYLGDWQSTHPPITKKVAQYTGGESCIPPAPVFGNLPE 255 T +GV H ++ E++L ++ A Y GGE N Sbjct: 180 TSARMALIGLGVSHPVLKQVAEQFLNMRGGL--GLSGAKANYRGGEIREQ------NGDS 231 Query: 256 LFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFVEN 315 L H E + A + LQ +LG G G + Q + V Sbjct: 232 LVHAAFVAESAVAGSAEANAFSVLQHVLGAGPHVKRGSNTTSHLHQAVAKATQQPFDVS- 290 Query: 316 CVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRAKNQLK 375 AFN SYSDSG+FGI AA ++ Q+ T A +L T +V AKN+LK Sbjct: 291 --AFNASYSDSGLFGIYTISQATAAGDVIKAAYNQV-KTIAQGNLSNT--DVQAAKNKLK 345 Query: 376 SSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFTGNVNNA 435 + LM++ES LE++G Q L+ G +P + ++ +I+ + DI A+ +G + A Sbjct: 346 AGYLMSVESSECFLEEVGSQALVAGSYMPPSTVLQQIDSVANADIINAAKKFVSGQKSMA 405 Query: 436 GNG 438 +G Sbjct: 406 ASG 408 >5GUP-v nrPDB Length = 453 Score = 132 bits (332), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 115/423 (27%), Positives = 189/423 (44%), Gaps = 19/423 (4%) Query: 18 NFKLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEG 77 + + + L NGL +A+ S +GL+I AGSR+E N G +H+L + +T+ Sbjct: 37 DLEFTRLPNGLVIASLENYAPASRIGLFIKAGSRYEDSNNLGTSHLLRLASSLTTKGASS 96 Query: 78 RAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKL 137 + +E +GG TS+RE++ Y D+ +++ + P+ E+ L Sbjct: 97 FKITRGIEAVGGKLSVTSTRESMAYTVECLRDDIEILMEFLLNVTAAPEFRRWEV--AAL 154 Query: 138 SAEYEIDE--VWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNKFY 195 ++ ID+ + P+ + E LH AAY L + L CP I ++ L Y + Sbjct: 155 QSQLRIDKAVAFQNPQAQVLENLHAAAYR-NALANSLYCPDYRIGKVTPDQLHYYVQNHF 213 Query: 196 TPENTVAAFVGVPHEKALELTEKYLGDWQSTHPPITKKVAQYTGGESCIPPAPVFGNLPE 255 T +GV H ++ E++L ++ A+Y GGE N Sbjct: 214 TSARMALIGLGVSHPVLKQVAERFLN--MRGGLGLSGAKAKYRGGEIRDQ------NGDS 265 Query: 256 LFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFVEN 315 L H + E + A + LQ +LG G G S LY V + + Sbjct: 266 LVHAALVAESAATGSAEANAFSVLQHVLGAGPHVK---RGSNATSSLYQAVAKGVHQPFD 322 Query: 316 CVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRAKNQLK 375 AFN SYSDSG+FGI I QAA A +VI A L+ +V AKN+LK Sbjct: 323 VSAFNASYSDSGLFGI--YTISQAA-SAGDVIKSAYDQVKAIAQGNLSNTDVQAAKNKLK 379 Query: 376 SSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFTGNVNNA 435 + LM++ES L+++G Q L+ G + + ++ +I+ + D+ A+ +G + A Sbjct: 380 AGYLMSVESSEGFLDEVGSQALVAGSYMQPSTVLQQIDSVADADVINAAKKFVSGRKSMA 439 Query: 436 GNG 438 +G Sbjct: 440 ASG 442 >3L72-A nrPDB Length = 446 Score = 124 bits (312), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 105/412 (25%), Positives = 192/412 (46%), Gaps = 33/412 (8%) Query: 12 NIARTDNFKLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKS 71 NI T+ +++L NGL+VA+ + +G++I AGSR+E G + ++ LAFK Sbjct: 10 NIPETN---VTTLDNGLRVASEESSQPTCTVGVWIGAGSRYENEKNNGAGYFVEHLAFKG 66 Query: 72 TEHVEGRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQE 131 T+ A + +E +G ++ +SRE + ++D+ K+++L+++ V+ + E + Sbjct: 67 TKKRPCAAFEKEVESMGAHFNGYTSREQTAFYIKALSKDMPKVVELLADVVQNCALEESQ 126 Query: 132 LQEQKLSAEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYR 191 +++++ E+ E+ V + LH A+ G L + E I +++ L Y Sbjct: 127 IEKERGVILQELKEMDNDMTNVTFDYLHATAFQGTALARTVEGTTENIKHLTRADLASYI 186 Query: 192 N-KFYTPENTVAAFVGVPHEKALELTEKYLGDWQSTHP----PITKKVAQYTGGE----- 241 + F P +AA G+ H++ ++ ++ T+ PI + ++TG E Sbjct: 187 DTHFKAPRMVLAAAGGISHKELVDAARQHFSGVSFTYKEDAVPILPR-CRFTGSEIRARD 245 Query: 242 SCIPPAPVFGNLPELFHIQIGFEGLPIDHPDIYALATLQTLLGG-GGSFSAGGPGKGMYS 300 +P A H+ + EG PD L ++G +F G GK + S Sbjct: 246 DALPVA----------HVALAVEGPGWADPDNVVLHVANAIIGRYDRTF---GGGKHLSS 292 Query: 301 RLYTHVLNQYYFVENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDL 360 RL + ++ + FN SYSD+G+FG P + + AQ + Sbjct: 293 RLAALAV-EHKLCHSFQTFNTSYSDTGLFGFHFVADPLSIDDMM-FCAQGEWMRLCTS-- 348 Query: 361 RLTEDEVSRAKNQLKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKI 412 TE EV RAKN L+S+++ L+ E +G +L +GR+I + E S+I Sbjct: 349 -TTESEVKRAKNHLRSAMVAQLDGTTPVCETIGSHLLNYGRRISLEEWDSRI 399 >2BCC-B nrPDB Length = 422 Score = 124 bits (311), Expect = 9e-29, Method: Compositional matrix adjust. Identities = 118/427 (27%), Positives = 193/427 (45%), Gaps = 27/427 (6%) Query: 18 NFKLSSLANGLKVAT--SNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHV 75 + +++ L NGL +A+ + +PG S +G++I AGSR+E + G +H+L + +T+ Sbjct: 6 DLEITKLPNGLVIASLENYSPG--STIGVFIKAGSRYENSSNLGTSHLLRLASSLTTKGA 63 Query: 76 EGRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQ 135 + +E +GG S+REN+ Y DV +++ + P+ E+ + Sbjct: 64 SSFKITRGIEAVGGKLSVESTRENMAYTVECLRDDVEILMEFLLNVTTAPEFRPWEVAD- 122 Query: 136 KLSAEYEIDE--VWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNK 193 L + +ID+ + P+ + E LH AAY L L CP I ++ L D+ Sbjct: 123 -LQPQLKIDKAVAFQNPQTHVIENLHAAAYR-NALADSLYCPDYRIGKVTSVELHDFVQN 180 Query: 194 FYTPENTVAAFVGVPHEKALELTEKYLGDWQSTHPPITKKVAQYTGGESCIPPAPVFGNL 253 +T +GV H + E+ L ++ A+Y GGE N Sbjct: 181 HFTSARMALVGLGVSHPVLKNVAEQLLNIRGGL--GLSGAKAKYRGGEIREQ------NG 232 Query: 254 PELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFV 313 L H I E I + A + LQ +LG G S LY V + Sbjct: 233 DSLVHAAIVAESAAIGGAEANAFSVLQHVLGANPHVKR---GLNATSSLYQAVAKGVHQP 289 Query: 314 ENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVI--AQQMYNTFANKDLRLTEDEVSRAK 371 + AFN SYSDSG+FG I QAA A +VI A T A + ++ + V AK Sbjct: 290 FDVSAFNASYSDSGLFG--FYTISQAA-YAGQVIKAAYNQVKTIAQGN--VSNENVQAAK 344 Query: 372 NQLKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFTGN 431 N+LK+ LM++ES LE++G Q L G P + ++ +I+ + D+ + A+ + Sbjct: 345 NKLKAKYLMSVESSEGFLEEVGSQALAAGSYNPPSTVLQQIDAVADADVIKAAKKFVSRQ 404 Query: 432 VNNAGNG 438 + A +G Sbjct: 405 KSMAASG 411 >3EOQ-A nrPDB Length = 406 Score = 93.2 bits (230), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 96/424 (22%), Positives = 181/424 (42%), Gaps = 47/424 (11%) Query: 19 FKLSSLANGLKVATSNTPGHFS-ALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEG 77 F+ + L NGL+V PG S ALG ++ G+R E + G +H L+ + FK E ++ Sbjct: 2 FREAELRNGLRVIAEVVPGARSVALGYFVKTGARDETKEESGVSHFLEHMVFKGPEDMDA 61 Query: 78 RAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKL 137 A+ + +G Y +S E +Y +V + +L L ++ +R P + E++ Q +KL Sbjct: 62 LAVNRAFDRMGAQYNAFTSEEATVYYGAVLPEFAYDLLGLFAKLLR-PALREEDFQTEKL 120 Query: 138 SAEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNKFYTP 197 EI +P + E + G LG+ ++ RE I ++++ + Y + Y P Sbjct: 121 VILEEIARYQDRPGFMAYEWARARFFQGHPLGNSVLGTRESITALTREGMAAYHRRRYLP 180 Query: 198 ENTVAAFVG-VPHEKALELTEKYLGDW-----QSTHPPITKKVAQYTGGESCIPPAPVFG 251 +N V A G V ++ L E+ W + +PP+T P FG Sbjct: 181 KNMVLAATGRVDFDRLLAEAERLTEAWPEGEAERAYPPLT----------------PAFG 224 Query: 252 ------NLPELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTH 305 ++ F G+ + L LLG GS RL+ Sbjct: 225 VEERPYEKARALYLVALFPGVAYQEEARFPGQVLAHLLGEEGS-----------GRLHFA 273 Query: 306 VLNQYYFVENCVAFNHSYSD-SGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTE 364 ++++ + +F +D +G F + P + + V+ +++ E Sbjct: 274 LVDK--GLAEVASFGLEEADRAGTFHAYVQADPARKGEVLAVLQEELDRLGREGV---GE 328 Query: 365 DEVSRAKNQLKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVA 424 +EV RAK L + L+ E+ + L +G + L GR + + E+ ++++ + +++ + Sbjct: 329 EEVERAKTPLATGLVFAGETPMQRLFHLGMEYLYTGRYLSLEEVKARVQRVTSREVNALL 388 Query: 425 EMIF 428 E F Sbjct: 389 ERGF 392 >6GIQ-A nrPDB Length = 457 Score = 76.6 bits (187), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 105/451 (23%), Positives = 193/451 (42%), Gaps = 35/451 (7%) Query: 2 LRNGVQRLYSNIARTDNFKLSSLANGLKVATSNTP-GHFSALGLYIDAGSRFEGRNLKGC 60 + N +R + T +++ L+NG+ VAT + P H +++G+ +G+ E G Sbjct: 10 VSNQFKRSLATAVATPKAEVTQLSNGIVVATEHNPSAHTASVGVVFGSGAANENPYNNGV 69 Query: 61 THILDRLAFKSTEHVEGRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSE 120 +++ + F S E+ A E L L SR+ Y S K L +++ Sbjct: 70 SNLWKNI-FLSKEN-SAVAAKEGLAL-----SSNISRDFQSYIVSSLPGSTDKSLDFLNQ 122 Query: 121 TVRFPK---ITEQELQEQKLSAEYEIDEVWMK--PELVLPELLHTAAYSGETLGSPLICP 175 + K ++ + K S ++ + P VL E LH+ A+ L P Sbjct: 123 SFIQQKANLLSSSNFEATKKSVLKQVQDFEENDHPNRVL-EHLHSTAFQNTPLSLPTRGT 181 Query: 176 RELIPSISKYYLLDYRNKFYTPENTVAAFVG-VPHEKALELTEKYLGDWQSTHPPITKKV 234 E + ++ L + N + N V G + HE + E Q+ P+ KK Sbjct: 182 LESLENLVVADLESFANNHFLNSNAVVVGTGNIKHEDLVNSIESKNLSLQTGTKPVLKKK 241 Query: 235 AQYTGGESCIPPAPVFGNLPELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGP 294 A + G E + LP+ + I + EG P++ P+ + + G +F Sbjct: 242 AAFLGSEVRLRD----DTLPKAW-ISLAVEGEPVNSPNYFVAKLAAQIFGSYNAFEPASR 296 Query: 295 GKGMYSRLYTHVLNQYYFVENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNT 354 +G+ +L ++ +Y +N F+ SY DSG++G S A + V +I ++ T Sbjct: 297 LQGI--KLLDNI-QEYQLCDNFNHFSLSYKDSGLWGFS------TATRNVTMIDDLIHFT 347 Query: 355 FANKD---LRLTEDEVSRAKNQLKSSLLMNLES--KLVELEDMGRQVLMHGRKIPVNEMI 409 + + +T+ EV RAK+ LK L ES + + +G +VL+ G K+ + E Sbjct: 348 LKQWNRLTISVTDTEVERAKSLLKLQLGQLYESGNPVNDANLLGAEVLIKGSKLSLGEAF 407 Query: 410 SKIEDLKPDDISRVA-EMIFTGNVNNAGNGK 439 KI+ + D+ A + ++ ++ AG G+ Sbjct: 408 KKIDAITVKDVKAWAGKRLWDQDIAIAGTGQ 438 >5EUF-A nrPDB Length = 419 Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 97/420 (23%), Positives = 173/420 (41%), Gaps = 38/420 (9%) Query: 23 SLANGLKVAT---SNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEGRA 79 +L NGL+V + N G LY GSR E G H+L+ L FKST++++ Sbjct: 12 TLKNGLQVVSVPLENKTGVIEVDVLY-KVGSRNEVMGKSGIAHMLEHLNFKSTKNLKAGE 70 Query: 80 MAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQE-LQEQKLS 138 + ++ GG ++S + Y ++ K L+L +ET+ + E E L E+++ Sbjct: 71 FDKIVKRFGGVSNASTSFDITRYFIKTSEANLDKSLELFAETMGSLNLKEDEFLPERQVV 130 Query: 139 AEYEIDEVWMKPELVLPELLHTAAYSGETLGSPL-ICPRELIPSISKYYLLD---YRNKF 194 AE + W + +L+ ++ + P P + I + L D + + + Sbjct: 131 AE---ERRWRTDNSPIG-MLYFRFFNTAYVYHPYHWTPIGFMDDIQNWTLKDIKKFHSLY 186 Query: 195 YTPENTVAAFVG-VPHEKALELTEKYLG-----DWQSTHPPITKKVAQYTGGESCIPPAP 248 Y P+N + VG V +K ELT+K+ D ++ P K+ Q G + + Sbjct: 187 YQPKNAIVLVVGDVNSQKVFELTKKHFESLKNLDEKAIPTPYMKEPKQ-DGARTAV---- 241 Query: 249 VFGNLPELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLN 308 V + L + +G++ H D AL L LLG G S S L + +++ Sbjct: 242 VHKDGVHLEWVALGYKVPAFKHKDQVALDALSKLLGEGKS-----------SWLQSELVD 290 Query: 309 QYYFVENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVS 368 + + N D +F P +A++ + K +T+ E+ Sbjct: 291 KKRLASQAFSHNMQLQDESVFLFIAGGNPNIKAEALQKEIVALLEKL--KKGEITQAELD 348 Query: 369 RAKNQLKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIF 428 + K K+ + NLES ++ + L+ + + + DLK D+ RVA F Sbjct: 349 KIKINQKADFISNLESS-SDVAGLFADYLVQNDLQGLTDYQQQFLDLKVSDLVRVANEYF 407 >3CX5-B nrPDB Length = 352 Score = 58.9 bits (141), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 43/173 (24%), Positives = 80/173 (46%), Gaps = 6/173 (3%) Query: 28 LKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEGRAMAETLELL 87 L V+ + P S L + + GSR+ ++ G H+L+R F++T + ELL Sbjct: 1 LTVSARDAPTKISTLAVKVHGGSRYATKD--GVAHLLNRFNFQNTNTRSALKLVRESELL 58 Query: 88 GGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKL-SAEYEIDEV 146 GG ++ T RE + +A+ D+ + +++ + EL E L +A Y+ Sbjct: 59 GGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVA 118 Query: 147 WMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNKFYTPEN 199 P + L+ + + LG+PL+ + + +S + D+ +K YT EN Sbjct: 119 EQCPVKSAEDQLYAITFR-KGLGNPLLY--DGVERVSLQDIKDFADKVYTKEN 168 >4NNZ-A nrPDB Length = 439 Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 95/431 (22%), Positives = 170/431 (39%), Gaps = 54/431 (12%) Query: 23 SLANGLKVATS---NTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEGRA 79 SL NGLKV P S L I GS +E L G +H L+ + FK + + Sbjct: 11 SLDNGLKVIVREDHRAPVVVSQLWYRI--GSSYETPGLTGLSHALEHMMFKGSRKLGPGE 68 Query: 80 MAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKLSA 139 + L LG ++ + Y + + L++ ++ ++ L + + Sbjct: 69 ASRVLRDLGAEENAFTTDDYTAYYQVLARDRLPVALEMEAD-----RMAHLSLPVDQFKS 123 Query: 140 EYEI--DEVWMK----PELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNK 193 E E+ +E ++ P + E AAY +P I + ++ L + Sbjct: 124 EIEVIKEERRLRTDDNPNALAFERFKAAAYPASGYHTPTIGWMADLQRMTIDDLRHWYES 183 Query: 194 FYTPENTVAAFVG-VPHEKALELTEKYLGD--WQSTHPPITKKVAQYTGGESCIPPAPVF 250 +Y P N VG V ++ L ++Y G+ W+ PP K + GE + V Sbjct: 184 WYAPNNATLVVVGDVTADEVKTLAKRYFGEIPWRQL-PPARKPLELAEPGERRL-KLYVR 241 Query: 251 GNLPELFHIQIGFE----GLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHV 306 LP L +GF G + ++ AL + LL GG +SA + SRL Sbjct: 242 TQLPNLI---MGFNVPSLGSSENPREVNALRLIGALLDGG--YSA-----RLASRLERG- 290 Query: 307 LNQYYFVENCVAFNHSYSDSGIFGISLSCIPQAAP-----QAVEVIAQQMYNTFANKDLR 361 E VA +Y D+ G SL + A P + +E + ++ DL+ Sbjct: 291 -------EELVAGASTYYDAFNRGDSLFVL-SATPNVQKGKTLEQVEAGLWKQL--DDLK 340 Query: 362 L---TEDEVSRAKNQLKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPD 418 + E+ R + Q+ + ++ +S + +G+ + +++ + ++ + PD Sbjct: 341 QNPPSAAEIERVRAQMIAGMVYEKDSIAAQASSIGQLESVGLSWKLIDQDLEALKAVTPD 400 Query: 419 DISRVAEMIFT 429 DI + A FT Sbjct: 401 DIQKAARTYFT 411 >4LIV-A nrPDB Length = 407 Score = 33.5 bits (75), Expect = 0.19, Method: Compositional matrix adjust. Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 2/126 (1%) Query: 44 LYIDAGSRFEGRNLKGC-THILDRLAFKSTEHVEGRAMAETLELLGGNYQCTSSRENLMY 102 LYI G EG L+ + + A + E + G A LGGNY + Sbjct: 213 LYIPPGFPHEGYALENAMNYSVGFRAPNTRELISGFADYVLQRELGGNYYSDPDVPPRAH 272 Query: 103 QASVFNQDVGKMLQLMSETVRFPKITEQELQEQKLSAEYEIDEVWMKPELVLPELLHTAA 162 A V Q++ K+ ++M E + P+ +Q E + +E+D +P P+ ++ A Sbjct: 273 PADVLPQEMDKLREMMLELINQPEHFKQWFGEFISQSRHELDIAPPEPPYQ-PDEIYDAL 331 Query: 163 YSGETL 168 GE L Sbjct: 332 KQGEVL 337 >2OHJ-A nrPDB Length = 404 Score = 31.6 bits (70), Expect = 0.85, Method: Compositional matrix adjust. Identities = 13/33 (39%), Positives = 18/33 (54%) Query: 163 YSGETLGSPLICPRELIPSISKYYLLDYRNKFY 195 +S + G L CP+ L I +Y L+D KFY Sbjct: 167 FSNDAFGQHLCCPQRLDREIPEYILMDAARKFY 199 >1Q2L-A nrPDB Length = 939 Score = 31.2 bits (69), Expect = 1.0, Method: Compositional matrix adjust. Identities = 26/145 (17%), Positives = 67/145 (46%), Gaps = 6/145 (4%) Query: 5 GVQRLYSNIARTD----NFKLSSLANGLKVATSNTPGHFSAL-GLYIDAGSRFEGRNLKG 59 G Q + I ++D ++ L NG+ V + P +L L + GS + +G Sbjct: 3 GWQPIQETIRKSDKDNRQYQAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQG 62 Query: 60 CTHILDRLAFK-STEHVEGRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLM 118 H L+ ++ S ++ + ++AE L++ GG++ +++ + V N + + + Sbjct: 63 LAHYLEHMSLMGSKKYPQADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRL 122 Query: 119 SETVRFPKITEQELQEQKLSAEYEI 143 ++ + P + ++ + ++ + E+ Sbjct: 123 ADAIAEPLLDKKYAERERNAVNAEL 147 >3WV8-A nrPDB Length = 218 Score = 30.0 bits (66), Expect = 2.3, Method: Compositional matrix adjust. Identities = 15/47 (31%), Positives = 24/47 (51%), Gaps = 2/47 (4%) Query: 197 PENTVAAFVGVP--HEKALELTEKYLGDWQSTHPPITKKVAQYTGGE 241 PEN +AA++ HE L T K + DW+ P + +V++ E Sbjct: 156 PENPIAAYLQAEGIHEHVLVGTGKLIRDWEPVTPHVLDRVSEVMTAE 202 >1YJS-A nrPDB Length = 419 Score = 29.3 bits (64), Expect = 4.0, Method: Compositional matrix adjust. Identities = 16/49 (32%), Positives = 25/49 (51%) Query: 333 LSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRAKNQLKSSLLMN 381 + +PQ PQ I Q+ A +L +E+ VSRA + + S+L N Sbjct: 1 MKYLPQQDPQVFAAIEQERKRQHAKIELIASENFVSRAVMEAQGSVLTN 49 >2HQN-A nrPDB Length = 109 Score = 28.9 bits (63), Expect = 5.8, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 34/73 (46%), Gaps = 9/73 (12%) Query: 89 GNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKLSAEYEIDEVWM 148 G+ + E ++Y+ GK ++++ R ++Q +S E +D +W Sbjct: 10 GDLTISPDEEKIIYKGREVEVK-GKPFEVLTHLARH--------RDQIVSKEQLLDAIWE 60 Query: 149 KPELVLPELLHTA 161 +PE+V P ++ A Sbjct: 61 EPEMVTPNVIEVA 73 >3TPL-A nrPDB Length = 433 Score = 28.5 bits (62), Expect = 7.2, Method: Compositional matrix adjust. Identities = 17/63 (26%), Positives = 30/63 (47%), Gaps = 10/63 (15%) Query: 252 NLPELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMY--SRLYTHVLNQ 309 ++P LF +Q+ G P++ ++ A GGS GG +Y S YT + + Sbjct: 185 HVPNLFSLQLCGAGFPLNQSEVLASV--------GGSMIIGGIDHSLYTGSLWYTPIRRE 236 Query: 310 YYF 312 +Y+ Sbjct: 237 WYY 239 >2HQR-A nrPDB Length = 223 Score = 28.1 bits (61), Expect = 7.9, Method: Compositional matrix adjust. Identities = 16/73 (21%), Positives = 34/73 (46%), Gaps = 9/73 (12%) Query: 89 GNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKLSAEYEIDEVWM 148 G+ + E ++Y+ GK ++++ R ++Q +S E +D +W Sbjct: 124 GDLTISPDEEKIIYKGREVEVK-GKPFEVLTHLARH--------RDQIVSKEQLLDAIWE 174 Query: 149 KPELVLPELLHTA 161 +PE+V P ++ A Sbjct: 175 EPEMVTPNVIEVA 187 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1HR7-A nrPDB 638 0.0 6HAW-A nrPDB 467 e-132 1BCC-A nrPDB 466 e-132 5XTH-AL nrPDB 454 e-128 3L72-A nrPDB 447 e-126 5XTH-AK nrPDB 434 e-122 6HAW-B nrPDB 434 e-122 5GUP-v nrPDB 430 e-121 2BCC-B nrPDB 429 e-120 3L73-B nrPDB 424 e-119 1HR8-B nrPDB 411 e-115 3HDI-A nrPDB 391 e-109 6GIQ-A nrPDB 355 3e-98 3EOQ-A nrPDB 322 2e-88 5EUF-A nrPDB 321 5e-88 4NNZ-A nrPDB 314 5e-86 3CX5-B nrPDB 170 9e-43 Sequences not found previously or not previously below threshold: 5CIO-A nrPDB 87 2e-17 1Q2L-A nrPDB 83 2e-16 3GO9-A nrPDB 71 9e-13 2FGE-A nrPDB 62 5e-10 1MX5-A nrPDB 37 0.016 5JY4-B nrPDB 34 0.19 3PDI-A nrPDB 32 0.39 3LVY-A nrPDB 32 0.70 1YXA-A nrPDB 32 0.79 5DYK-A nrPDB 31 1.2 5FET-A nrPDB 29 5.5 >1HR7-A nrPDB Length = 475 Score = 638 bits (1644), Expect = 0.0, Method: Composition-based stats. Identities = 467/469 (99%), Positives = 467/469 (99%) Query: 14 ARTDNFKLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTE 73 ARTDNFKLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTE Sbjct: 1 ARTDNFKLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTE 60 Query: 74 HVEGRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQ 133 HVEGRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQ Sbjct: 61 HVEGRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQ 120 Query: 134 EQKLSAEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNK 193 EQKLSAEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPR LIPSISKYYLLDYRNK Sbjct: 121 EQKLSAEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRGLIPSISKYYLLDYRNK 180 Query: 194 FYTPENTVAAFVGVPHEKALELTEKYLGDWQSTHPPITKKVAQYTGGESCIPPAPVFGNL 253 FYTPENTVAAFVGVPHEKALELT KYLGDWQSTHPPITKKVAQYTGGESCIPPAPVFGNL Sbjct: 181 FYTPENTVAAFVGVPHEKALELTGKYLGDWQSTHPPITKKVAQYTGGESCIPPAPVFGNL 240 Query: 254 PELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFV 313 PELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFV Sbjct: 241 PELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFV 300 Query: 314 ENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRAKNQ 373 ENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRAKNQ Sbjct: 301 ENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRAKNQ 360 Query: 374 LKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFTGNVN 433 LKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFTGNVN Sbjct: 361 LKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFTGNVN 420 Query: 434 NAGNGKGRATVVMQGDRGSFGDVENVLKAYGLGNSSSSKNDSPKKKGWF 482 NAGNGKGRATVVMQGDRGSFGDVENVLKAYGLGNSSSSKNDSPKKKGWF Sbjct: 421 NAGNGKGRATVVMQGDRGSFGDVENVLKAYGLGNSSSSKNDSPKKKGWF 469 >6HAW-A nrPDB Length = 438 Score = 467 bits (1202), Expect = e-132, Method: Composition-based stats. Identities = 111/435 (25%), Positives = 202/435 (46%), Gaps = 20/435 (4%) Query: 6 VQRLYSNIARTDNFKLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILD 65 + ++ T ++S L NGL+VA+ + +G++IDAGSR+E G + ++ Sbjct: 3 YAQALQSVPET---QVSQLDNGLRVASEQSSQPTCTVGVWIDAGSRYESEKNNGAGYFVE 59 Query: 66 RLAFKSTEHVEGRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFP 125 LAFK T++ G A+ + +E +G + S+RE+ Y ++D+ K ++L+++ V+ Sbjct: 60 HLAFKGTKNRPGNALEKEVESMGAHLNAYSTREHTAYYIKALSKDLPKAVELLADIVQNC 119 Query: 126 KITEQELQEQKLSAEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKY 185 + + ++++++ E+ E V+ LH A+ G L + P E + +S+ Sbjct: 120 SLEDSQIEKERDVILQELQENDTSMRDVVFNYLHATAFQGTPLAQSVEGPSENVRKLSRA 179 Query: 186 YLLDYRNKFY-TPENTVAAFVGVPHEKALELTEKYLGDWQSTHPPITKKVAQYTGGESCI 244 L +Y ++ Y P +AA G+ H + L+L +K+ T ++TG + C Sbjct: 180 DLTEYLSRHYKAPRMVLAAAGGLEHRQLLDLAQKHFSGLSGVP---TLSPCRFTGSQICH 236 Query: 245 PPAPVFGNLPELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYT 304 + L H+ I EG HPD AL ++G G G + S L + Sbjct: 237 RE-----DGLPLAHVAIAVEGPGWAHPDNVALQVANAIIGHYDCTY--GGGAHLSSPLAS 289 Query: 305 HVLNQYYFVENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTE 364 + ++ FN Y+D+G+ G C + + V+ Q + TE Sbjct: 290 -IAATNKLCQSFQTFNICYADTGLLGAHFVCDHMSIDDMMFVLQGQWMRLCTSA----TE 344 Query: 365 DEVSRAKNQLKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVA 424 EV R KN L+++L+ +L+ ED+GR +L +GR+IP+ E S+I ++ + V Sbjct: 345 SEVLRGKNLLRNALVSHLDGTTPVCEDIGRSLLTYGRRIPLAEWESRIAEVDARVVREVC 404 Query: 425 EMIF-TGNVNNAGNG 438 F AG G Sbjct: 405 SKYFYDQCPAVAGFG 419 >1BCC-A nrPDB Length = 446 Score = 466 bits (1200), Expect = e-132, Method: Composition-based stats. Identities = 114/440 (25%), Positives = 209/440 (47%), Gaps = 24/440 (5%) Query: 6 VQRLYSNIARTDNFKLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILD 65 + ++ T ++S L NG++VA+ + +G++IDAGSR+E G + L+ Sbjct: 4 YAQALQSVPET---QVSQLDNGVRVASEQSSQPTCTVGVWIDAGSRYESEKNNGAGYFLE 60 Query: 66 RLAFKSTEHVEGRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFP 125 LAFK T++ A+ + +E +G + SSRE+ Y ++DV K ++L+++ V+ Sbjct: 61 HLAFKGTKNRPQNALEKEVESMGAHLNAYSSREHTAYYIKALSKDVPKAVELLADIVQNC 120 Query: 126 KITEQELQEQKLSAEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKY 185 + + ++++++ E+ E V+ LH A+ G L + P E I +S+ Sbjct: 121 SLEDSQIEKERDVIVRELQENDTSMREVVFNYLHATAFQGTGLAQSVEGPSENIRKLSRA 180 Query: 186 YLLDYRNKFYT-PENTVAAFVGVPHEKALELTEKYLGDWQSTH-----PPITKKVAQYTG 239 L +Y + YT P +AA GV H++ LEL +K+ G T+ P ++K ++TG Sbjct: 181 DLTEYLSTHYTAPRMVLAAAGGVEHQQLLELAQKHFGGVPFTYDDDAVPTLSK--CRFTG 238 Query: 240 GESCIPPAPVFGNLPELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMY 299 + + L H+ I EG HPD+ AL ++G G G Sbjct: 239 SQIRHRE-----DGLPLAHVAIAVEGPGWAHPDLVALQVANAIIGHYD--RTYGGGLHSS 291 Query: 300 SRLYTHVLNQYYFVENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKD 359 S L + + ++ F+ YS++G+FG C + + V+ Q + Sbjct: 292 SPLASIAVTNK-LCQSFQTFSICYSETGLFGFYFVCDRMSIDDMMFVLQGQWMRLCTS-- 348 Query: 360 LRLTEDEVSRAKNQLKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDD 419 ++E EV R KN L+++L+ +L+ ED+GR++L +GR+IP+ E ++ ++ Sbjct: 349 --ISESEVLRGKNFLRNALVSHLDGTTPVCEDIGRELLTYGRRIPLEEWEERLAEVDARM 406 Query: 420 ISRVAEMI-FTGNVNNAGNG 438 + V + AG G Sbjct: 407 VREVCSKYIYDQCPAVAGPG 426 >5XTH-AL nrPDB Length = 446 Score = 454 bits (1168), Expect = e-128, Method: Composition-based stats. Identities = 110/438 (25%), Positives = 200/438 (45%), Gaps = 20/438 (4%) Query: 6 VQRLYSNIARTDNFKLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILD 65 + + T ++S L NGL+VA+ + +G++ID GSRFE G + L+ Sbjct: 4 FAQALQFVPET---QVSLLDNGLRVASEQSSQPTCTVGVWIDVGSRFETEKNNGAGYFLE 60 Query: 66 RLAFKSTEHVEGRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFP 125 LAFK T++ G A+ + +E +G + S+RE+ Y ++D+ K ++L+ + V+ Sbjct: 61 HLAFKGTKNRPGSALEKEVESMGAHLNAYSTREHTAYYIKALSKDLPKAVELLGDIVQNC 120 Query: 126 KITEQELQEQKLSAEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKY 185 + + ++++++ E+ E V+ LH A+ G L + P E + +S+ Sbjct: 121 SLEDSQIEKERDVILREMQENDASMRDVVFNYLHATAFQGTPLAQAVEGPSENVRKLSRA 180 Query: 186 YLLDYRNKFY-TPENTVAAFVGVPHEKALELTEKYLGD--WQSTHPPI-TKKVAQYTGGE 241 L +Y + Y P +AA GV H++ L+L +K+LG W + T ++TG E Sbjct: 181 DLTEYLSTHYKAPRMVLAAAGGVEHQQLLDLAQKHLGGIPWTYAEDAVPTLTPCRFTGSE 240 Query: 242 SCIPPAPVFGNLPELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSR 301 + H+ I EG PD AL ++G G G + S Sbjct: 241 IRH-----RDDALPFAHVAIAVEGPGWASPDNVALQVANAIIGHYDCTY--GGGVHLSSP 293 Query: 302 LYTHVLNQYYFVENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLR 361 L + + ++ F+ Y+++G+ G C + V+ Q + Sbjct: 294 LASGAVANK-LCQSFQTFSICYAETGLLGAHFVCDRMKIDDMMFVLQGQWMRLCTSA--- 349 Query: 362 LTEDEVSRAKNQLKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDIS 421 TE EV+R KN L+++L+ +L+ ED+GR +L +GR+IP+ E S+I ++ + Sbjct: 350 -TESEVARGKNILRNALVSHLDGTTPVCEDIGRSLLTYGRRIPLAEWESRIAEVDASVVR 408 Query: 422 RVAEMI-FTGNVNNAGNG 438 + + AG G Sbjct: 409 EICSKYIYDQCPAVAGYG 426 >3L72-A nrPDB Length = 446 Score = 447 bits (1150), Expect = e-126, Method: Composition-based stats. Identities = 102/439 (23%), Positives = 195/439 (44%), Gaps = 22/439 (5%) Query: 6 VQRLYSNIARTDNFKLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILD 65 + NI T+ +++L NGL+VA+ + +G++I AGSR+E G + ++ Sbjct: 4 YAQTLQNIPETN---VTTLDNGLRVASEESSQPTCTVGVWIGAGSRYENEKNNGAGYFVE 60 Query: 66 RLAFKSTEHVEGRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFP 125 LAFK T+ A + +E +G ++ +SRE + ++D+ K+++L+++ V+ Sbjct: 61 HLAFKGTKKRPCAAFEKEVESMGAHFNGYTSREQTAFYIKALSKDMPKVVELLADVVQNC 120 Query: 126 KITEQELQEQKLSAEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKY 185 + E ++++++ E+ E+ V + LH A+ G L + E I +++ Sbjct: 121 ALEESQIEKERGVILQELKEMDNDMTNVTFDYLHATAFQGTALARTVEGTTENIKHLTRA 180 Query: 186 YLLDYRNKFY-TPENTVAAFVGVPHEKALELTEKYLGDWQSTHP----PITKKVAQYTGG 240 L Y + + P +AA G+ H++ ++ ++ T+ PI + ++TG Sbjct: 181 DLASYIDTHFKAPRMVLAAAGGISHKELVDAARQHFSGVSFTYKEDAVPILPR-CRFTGS 239 Query: 241 ESCIPPAPVFGNLPELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYS 300 E + + H+ + EG PD L ++G G GK + S Sbjct: 240 EIR-----ARDDALPVAHVALAVEGPGWADPDNVVLHVANAIIGRYD--RTFGGGKHLSS 292 Query: 301 RLYTHVLNQYYFVENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDL 360 RL + ++ + FN SYSD+G+FG P + + + + Sbjct: 293 RLA-ALAVEHKLCHSFQTFNTSYSDTGLFGFHFVADPLSIDDMMFCAQGEWMRLCTS--- 348 Query: 361 RLTEDEVSRAKNQLKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDI 420 TE EV RAKN L+S+++ L+ E +G +L +GR+I + E S+I + + Sbjct: 349 -TTESEVKRAKNHLRSAMVAQLDGTTPVCETIGSHLLNYGRRISLEEWDSRISAVDARMV 407 Query: 421 SRVAEMI-FTGNVNNAGNG 438 V + A G Sbjct: 408 RDVCSKYIYDKCPALAAVG 426 >5XTH-AK nrPDB Length = 419 Score = 434 bits (1116), Expect = e-122, Method: Composition-based stats. Identities = 111/422 (26%), Positives = 181/422 (42%), Gaps = 15/422 (3%) Query: 17 DNFKLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVE 76 + + + L NGL +A+ S +GL+I AGSR+E + G TH+L + +T+ Sbjct: 2 QDLEFTKLPNGLVIASLENYSPVSRIGLFIKAGSRYEDFSNLGTTHLLRLTSSLTTKGAS 61 Query: 77 GRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQK 136 + +E +GG T++REN+ Y DV +++ + P+ E+ + + Sbjct: 62 SFKITRGIEAVGGKLSVTATRENMAYTVECLRGDVDILMEFLLNVTTAPEFRRWEVADLQ 121 Query: 137 LSAEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNKFYT 196 + + + P+ + E LH AAY L +PL CP I ++ L + +T Sbjct: 122 PQLKIDKAVAFQNPQTHVIENLHAAAYR-NALANPLYCPDYRIGKVTSEELHYFVQNHFT 180 Query: 197 PENTVAAFVGVPHEKALELTEKYLGDWQSTHPPITKKVAQYTGGESCIPPAPVFGNLPEL 256 +GV H ++ E++L ++ A Y GGE N L Sbjct: 181 SARMALIGLGVSHPVLKQVAEQFLNMRGGL--GLSGAKANYRGGEIREQ------NGDSL 232 Query: 257 FHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFVENC 316 H E + A + LQ +LG G G S L+ V + Sbjct: 233 VHAAFVAESAVAGSAEANAFSVLQHVLGAGPHVK---RGSNTTSHLHQAVAKATQQPFDV 289 Query: 317 VAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRAKNQLKS 376 AFN SYSDSG+FGI AA VI L+ +V AKN+LK+ Sbjct: 290 SAFNASYSDSGLFGIYTISQATAAGD---VIKAAYNQVKTIAQGNLSNTDVQAAKNKLKA 346 Query: 377 SLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFTGNVNNAG 436 LM++ES LE++G Q L+ G +P + ++ +I+ + DI A+ +G + A Sbjct: 347 GYLMSVESSECFLEEVGSQALVAGSYMPPSTVLQQIDSVANADIINAAKKFVSGQKSMAA 406 Query: 437 NG 438 +G Sbjct: 407 SG 408 >6HAW-B nrPDB Length = 413 Score = 434 bits (1115), Expect = e-122, Method: Composition-based stats. Identities = 111/422 (26%), Positives = 177/422 (41%), Gaps = 20/422 (4%) Query: 17 DNFKLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVE 76 + + + L NGL +A+ S +GL+I AGSR+E N G +H+L + +T+ Sbjct: 1 QDLEFTRLPNGLVIASLENYAPASRIGLFIKAGSRYENSNNLGTSHLLRLASSLTTKGAS 60 Query: 77 GRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQK 136 + +E +GG TS+REN+ Y DV +++ + P+ E+ + Sbjct: 61 SFKITRGIEAVGGKLSVTSTRENMAYTVECLRDDVDILMEFLLNVTTAPEFRRWEVAALQ 120 Query: 137 LSAEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNKFYT 196 + P+ + E LH AAY L + L CP I ++ L DY +T Sbjct: 121 PQLRIDKAVALQNPQAHVIENLHAAAYR-NALANSLYCPDYRIGKVTPVELHDYVQNHFT 179 Query: 197 PENTVAAFVGVPHEKALELTEKYLGDWQSTHPPITKKVAQYTGGESCIPPAPVFGNLPEL 256 +GV H ++ E++L A+Y GGE N L Sbjct: 180 SARMALIGLGVSHPVLKQVAEQFLNIRGGA-------KAKYHGGEIREQ------NGDSL 226 Query: 257 FHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFVENC 316 H + E I + A + LQ +LG G G S LY V + + Sbjct: 227 VHAALVAESAAIGSAEANAFSVLQHVLGAGPHVK---RGSNATSSLYQAVAKGVHQPFDV 283 Query: 317 VAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRAKNQLKS 376 AFN SYSDSG+FG +A VI L+ +V AKN+LK+ Sbjct: 284 SAFNASYSDSGLFGFYTISQAASAGD---VIKAAYNQVKTIAQGNLSNPDVQAAKNKLKA 340 Query: 377 SLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFTGNVNNAG 436 LM++ES L+++G Q L G P + ++ +I+ + D+ A+ +G + A Sbjct: 341 GYLMSVESSEGFLDEVGSQALAAGSYTPPSTVLQQIDAVADADVINAAKKFVSGRKSMAA 400 Query: 437 NG 438 +G Sbjct: 401 SG 402 >5GUP-v nrPDB Length = 453 Score = 430 bits (1104), Expect = e-121, Method: Composition-based stats. Identities = 108/422 (25%), Positives = 181/422 (42%), Gaps = 15/422 (3%) Query: 17 DNFKLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVE 76 + + + L NGL +A+ S +GL+I AGSR+E N G +H+L + +T+ Sbjct: 36 QDLEFTRLPNGLVIASLENYAPASRIGLFIKAGSRYEDSNNLGTSHLLRLASSLTTKGAS 95 Query: 77 GRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQK 136 + +E +GG TS+RE++ Y D+ +++ + P+ E+ + Sbjct: 96 SFKITRGIEAVGGKLSVTSTRESMAYTVECLRDDIEILMEFLLNVTAAPEFRRWEVAALQ 155 Query: 137 LSAEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNKFYT 196 + + P+ + E LH AAY L + L CP I ++ L Y +T Sbjct: 156 SQLRIDKAVAFQNPQAQVLENLHAAAYR-NALANSLYCPDYRIGKVTPDQLHYYVQNHFT 214 Query: 197 PENTVAAFVGVPHEKALELTEKYLGDWQSTHPPITKKVAQYTGGESCIPPAPVFGNLPEL 256 +GV H ++ E++L ++ A+Y GGE N L Sbjct: 215 SARMALIGLGVSHPVLKQVAERFLNMRGGL--GLSGAKAKYRGGEIRDQ------NGDSL 266 Query: 257 FHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFVENC 316 H + E + A + LQ +LG G G S LY V + + Sbjct: 267 VHAALVAESAATGSAEANAFSVLQHVLGAGPHVK---RGSNATSSLYQAVAKGVHQPFDV 323 Query: 317 VAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRAKNQLKS 376 AFN SYSDSG+FGI +A VI A L+ +V AKN+LK+ Sbjct: 324 SAFNASYSDSGLFGIYTISQAASAGD---VIKSAYDQVKAIAQGNLSNTDVQAAKNKLKA 380 Query: 377 SLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFTGNVNNAG 436 LM++ES L+++G Q L+ G + + ++ +I+ + D+ A+ +G + A Sbjct: 381 GYLMSVESSEGFLDEVGSQALVAGSYMQPSTVLQQIDSVADADVINAAKKFVSGRKSMAA 440 Query: 437 NG 438 +G Sbjct: 441 SG 442 >2BCC-B nrPDB Length = 422 Score = 429 bits (1102), Expect = e-120, Method: Composition-based stats. Identities = 107/425 (25%), Positives = 179/425 (42%), Gaps = 15/425 (3%) Query: 14 ARTDNFKLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTE 73 + +++ L NGL +A+ S +G++I AGSR+E + G +H+L + +T+ Sbjct: 2 PHPQDLEITKLPNGLVIASLENYSPGSTIGVFIKAGSRYENSSNLGTSHLLRLASSLTTK 61 Query: 74 HVEGRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQ 133 + +E +GG S+REN+ Y DV +++ + P+ E+ Sbjct: 62 GASSFKITRGIEAVGGKLSVESTRENMAYTVECLRDDVEILMEFLLNVTTAPEFRPWEVA 121 Query: 134 EQKLSAEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNK 193 + + + + + P+ + E LH AAY L L CP I ++ L D+ Sbjct: 122 DLQPQLKIDKAVAFQNPQTHVIENLHAAAYR-NALADSLYCPDYRIGKVTSVELHDFVQN 180 Query: 194 FYTPENTVAAFVGVPHEKALELTEKYLGDWQSTHPPITKKVAQYTGGESCIPPAPVFGNL 253 +T +GV H + E+ L ++ A+Y GGE N Sbjct: 181 HFTSARMALVGLGVSHPVLKNVAEQLLNIRGGL--GLSGAKAKYRGGEIREQ------NG 232 Query: 254 PELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFV 313 L H I E I + A + LQ +LG G S LY V + Sbjct: 233 DSLVHAAIVAESAAIGGAEANAFSVLQHVLGANPHVK---RGLNATSSLYQAVAKGVHQP 289 Query: 314 ENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRAKNQ 373 + AFN SYSDSG+FG A A +VI ++ + V AKN+ Sbjct: 290 FDVSAFNASYSDSGLFGFYTI---SQAAYAGQVIKAAYNQVKTIAQGNVSNENVQAAKNK 346 Query: 374 LKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFTGNVN 433 LK+ LM++ES LE++G Q L G P + ++ +I+ + D+ + A+ + + Sbjct: 347 LKAKYLMSVESSEGFLEEVGSQALAAGSYNPPSTVLQQIDAVADADVIKAAKKFVSRQKS 406 Query: 434 NAGNG 438 A +G Sbjct: 407 MAASG 411 >3L73-B nrPDB Length = 441 Score = 424 bits (1090), Expect = e-119, Method: Composition-based stats. Identities = 109/425 (25%), Positives = 187/425 (44%), Gaps = 15/425 (3%) Query: 14 ARTDNFKLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTE 73 ++ +++ L NGL +A+ S +G++I AGSR+E G H+L + +T+ Sbjct: 21 PGAEDLEITKLPNGLIIASLENFSPASRIGVFIKAGSRYETTANLGTAHLLRLASPLTTK 80 Query: 74 HVEGRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQ 133 + +E +GG+ S+RE + Y V +++ + P+ E+ Sbjct: 81 GASSFRITRGIEAVGGSLSVYSTREKMTYCVECLRDHVDTVMEYLLNVTTAPEFRPWEVT 140 Query: 134 EQKLSAEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNK 193 + + + + + P++ + E LH AAY L +PL CP I I+ L + Sbjct: 141 DLQPQLKVDKAVAFQSPQVGVLENLHAAAYK-TALANPLYCPDYRIGKITSEQLHHFVQN 199 Query: 194 FYTPENTVAAFVGVPHEKALELTEKYLGDWQSTHPPITKKVAQYTGGESCIPPAPVFGNL 253 +T +GV H ++ E++L + A Y GGE N Sbjct: 200 NFTSARMALVGIGVKHSDLKQVAEQFLNIRSGAGT--SSAKATYWGGEIREQ------NG 251 Query: 254 PELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFV 313 L H + EG + + A + LQ +LG G G + S+LY V Sbjct: 252 HSLVHAAVVTEGAAVGSAEANAFSVLQHVLGAGPLIK---RGSSVTSKLYQGVAKATTQP 308 Query: 314 ENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRAKNQ 373 + AFN +YSDSG+FG A A EVI M A +TE++V++AKNQ Sbjct: 309 FDASAFNVNYSDSGLFGFYTI---SQAAHAGEVIRAAMNQLKAAAQGGVTEEDVTKAKNQ 365 Query: 374 LKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFTGNVN 433 LK++ LM++E+ L ++G + L+ G + + KI+ + D+ A+ +G + Sbjct: 366 LKATYLMSVETAQGLLNEIGSEALLSGTHTAPSVVAQKIDSVTSADVVNAAKKFVSGKKS 425 Query: 434 NAGNG 438 A +G Sbjct: 426 MAASG 430 >1HR8-B nrPDB Length = 443 Score = 411 bits (1055), Expect = e-115, Method: Composition-based stats. Identities = 115/430 (26%), Positives = 202/430 (46%), Gaps = 8/430 (1%) Query: 13 IARTDNFKLSSLANGLKVATSNTPGHFS-ALGLYIDAGSRFEGRNLKGCTHILDRLAFKS 71 ++ + S L NGL +AT P S +G+++DAGSR E G H L LAFK Sbjct: 1 ASQIPGTRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLQHLAFKG 60 Query: 72 TEHVEGRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQE 131 T++ + + +E +G + +SREN +Y A +D+ K + ++S+ + + Sbjct: 61 TQNRPQQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSA 120 Query: 132 LQEQKLSAEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYR 191 ++ ++ E +EV + V+ + LH Y + LG ++ P + I SI++ L DY Sbjct: 121 IERERDVIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYI 180 Query: 192 NKFYTPENTVAAFVG-VPHEKALELTEKYLGDWQSTHPPITKKVAQYTGGESCIPPAPVF 250 K Y + V A G V HEK ++ +KY G + P+ + C + Sbjct: 181 TKNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIK 240 Query: 251 GNLPELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQY 310 N HI I EG+ PD + Q ++G A G G S L Sbjct: 241 ENTLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWD--RAIGTGTNSPSPLAVAASQNG 298 Query: 311 YFVENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFAN-KDLRLTEDEVSR 369 + ++F+ SY+DSG++G+ + V +I ++ + K ++++ EV+R Sbjct: 299 SLANSYMSFSTSYADSGLWGMYIVTDSN--EHNVRLIVNEILKEWKRIKSGKISDAEVNR 356 Query: 370 AKNQLKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAE-MIF 428 AK QLK++LL++L+ +ED+GRQV+ G+++ E+ +++ + DDI A + Sbjct: 357 AKAQLKAALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQ 416 Query: 429 TGNVNNAGNG 438 V+ G Sbjct: 417 NKPVSMVALG 426 >3HDI-A nrPDB Length = 421 Score = 391 bits (1003), Expect = e-109, Method: Composition-based stats. Identities = 109/422 (25%), Positives = 201/422 (47%), Gaps = 26/422 (6%) Query: 23 SLANGLKVATSNTPGHFS-ALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEGRAMA 81 +L NG+++ T S ++G+++ GSR+E G +H L+ + FK T + +A Sbjct: 6 TLDNGVRIITEKMSTVRSVSIGIWVGTGSRYESAEENGISHFLEHMFFKGTNTRSAQEIA 65 Query: 82 ETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKLSAEY 141 E + +GG +S+E Y A V + G+ + +S+ ++EL++++ Sbjct: 66 EFFDSIGGQVNAFTSKEYTCYYAKVLDDHAGQAIDTLSDMFFHSTFQKEELEKERKVVFE 125 Query: 142 EIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNKFYTPENTV 201 EI V P+ ++ +LL +A Y +LG P++ E + S ++ L Y ++FYT + V Sbjct: 126 EIKMVDDTPDDIVHDLLSSATYGKHSLGYPILGTVETLNSFNEGMLRHYMDRFYTGDYVV 185 Query: 202 AAFVGVPHEKALELTEKYLGDWQSTHPPITKKVAQYTGGESC-IPPAPVFGNLPELFHIQ 260 + G H++ ++ + T + Y G + +P V E H+ Sbjct: 186 ISVAGNVHDELIDKIK-------ETFSQVKPTTYNYQGEKPMFLPNRIVRKKETEQAHLC 238 Query: 261 IGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFVENCVAFN 320 +G+ GLPI D+YAL L +LGG M SRL+ + + + +++ Sbjct: 239 LGYPGLPIGDKDVYALVLLNNVLGG-----------SMSSRLFQDIREKRGLCYSVFSYH 287 Query: 321 HSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRAKNQLKSSLLM 380 S+ DSG+ I V I Q+ + A K LTE E+ K QLK SL++ Sbjct: 288 SSFRDSGMLTIYAGTGHDQLDDLVYSI-QETTSALAEKG--LTEKELENGKEQLKGSLML 344 Query: 381 NLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFTGNVNNA---GN 437 +LES + G+ L+ + ++EMI +I ++ D+SR+A+++ + + + + N Sbjct: 345 SLESTNSRMSRNGKNELLLKKHRSLDEMIEQINAVQKQDVSRLAKILLSASPSISLINAN 404 Query: 438 GK 439 G+ Sbjct: 405 GE 406 >6GIQ-A nrPDB Length = 457 Score = 355 bits (910), Expect = 3e-98, Method: Composition-based stats. Identities = 104/451 (23%), Positives = 191/451 (42%), Gaps = 35/451 (7%) Query: 2 LRNGVQRLYSNIARTDNFKLSSLANGLKVATSNTP-GHFSALGLYIDAGSRFEGRNLKGC 60 + N +R + T +++ L+NG+ VAT + P H +++G+ +G+ E G Sbjct: 10 VSNQFKRSLATAVATPKAEVTQLSNGIVVATEHNPSAHTASVGVVFGSGAANENPYNNGV 69 Query: 61 THILDRLAFKSTEHVEGRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSE 120 +++ + F S E+ A E L SR+ Y S K L +++ Sbjct: 70 SNLWKNI-FLSKEN-SAVAAKEGLA-----LSSNISRDFQSYIVSSLPGSTDKSLDFLNQ 122 Query: 121 TVRFPK---ITEQELQEQKLSAEYEIDEVWMK--PELVLPELLHTAAYSGETLGSPLICP 175 + K ++ + K S ++ + P VL E LH+ A+ L P Sbjct: 123 SFIQQKANLLSSSNFEATKKSVLKQVQDFEENDHPNRVL-EHLHSTAFQNTPLSLPTRGT 181 Query: 176 RELIPSISKYYLLDYRNKFYTPENTVAAFVG-VPHEKALELTEKYLGDWQSTHPPITKKV 234 E + ++ L + N + N V G + HE + E Q+ P+ KK Sbjct: 182 LESLENLVVADLESFANNHFLNSNAVVVGTGNIKHEDLVNSIESKNLSLQTGTKPVLKKK 241 Query: 235 AQYTGGESCIPPAPVFGNLPELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGP 294 A + G E + LP+ I + EG P++ P+ + + G +F Sbjct: 242 AAFLGSEVRLRD----DTLPKA-WISLAVEGEPVNSPNYFVAKLAAQIFGSYNAFEPASR 296 Query: 295 GKGMYSRLYTHVLNQYYFVENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNT 354 +G+ +L ++ +Y +N F+ SY DSG++G S A + V +I ++ T Sbjct: 297 LQGI--KLLDNI-QEYQLCDNFNHFSLSYKDSGLWGFS------TATRNVTMIDDLIHFT 347 Query: 355 FANKD---LRLTEDEVSRAKNQLKSSLLMNLES--KLVELEDMGRQVLMHGRKIPVNEMI 409 + + +T+ EV RAK+ LK L ES + + +G +VL+ G K+ + E Sbjct: 348 LKQWNRLTISVTDTEVERAKSLLKLQLGQLYESGNPVNDANLLGAEVLIKGSKLSLGEAF 407 Query: 410 SKIEDLKPDDISRVA-EMIFTGNVNNAGNGK 439 KI+ + D+ A + ++ ++ AG G+ Sbjct: 408 KKIDAITVKDVKAWAGKRLWDQDIAIAGTGQ 438 >3EOQ-A nrPDB Length = 406 Score = 322 bits (825), Expect = 2e-88, Method: Composition-based stats. Identities = 92/418 (22%), Positives = 177/418 (42%), Gaps = 35/418 (8%) Query: 19 FKLSSLANGLKVATSNTPGHFS-ALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEG 77 F+ + L NGL+V PG S ALG ++ G+R E + G +H L+ + FK E ++ Sbjct: 2 FREAELRNGLRVIAEVVPGARSVALGYFVKTGARDETKEESGVSHFLEHMVFKGPEDMDA 61 Query: 78 RAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKL 137 A+ + +G Y +S E +Y +V + +L L ++ +R P + E++ Q +KL Sbjct: 62 LAVNRAFDRMGAQYNAFTSEEATVYYGAVLPEFAYDLLGLFAKLLR-PALREEDFQTEKL 120 Query: 138 SAEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNKFYTP 197 EI +P + E + G LG+ ++ RE I ++++ + Y + Y P Sbjct: 121 VILEEIARYQDRPGFMAYEWARARFFQGHPLGNSVLGTRESITALTREGMAAYHRRRYLP 180 Query: 198 ENTVAAFVG-VPHEKALELTEKYLGDW-----QSTHPPITKKVAQYTGGESCIPPAPVFG 251 +N V A G V ++ L E+ W + +PP+T G E Sbjct: 181 KNMVLAATGRVDFDRLLAEAERLTEAWPEGEAERAYPPLTPAF----GVEER------PY 230 Query: 252 NLPELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYY 311 ++ F G+ + L LLG GS RL+ ++++ Sbjct: 231 EKARALYLVALFPGVAYQEEARFPGQVLAHLLGEEGS-----------GRLHFALVDK-- 277 Query: 312 FVENCVAFNHSYSD-SGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRA 370 + +F +D +G F + P + + V+ +++ + RA Sbjct: 278 GLAEVASFGLEEADRAGTFHAYVQADPARKGEVLAVLQEELDRLGREGVGEEEVE---RA 334 Query: 371 KNQLKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIF 428 K L + L+ E+ + L +G + L GR + + E+ ++++ + +++ + E F Sbjct: 335 KTPLATGLVFAGETPMQRLFHLGMEYLYTGRYLSLEEVKARVQRVTSREVNALLERGF 392 >5EUF-A nrPDB Length = 419 Score = 321 bits (822), Expect = 5e-88, Method: Composition-based stats. Identities = 90/425 (21%), Positives = 164/425 (38%), Gaps = 26/425 (6%) Query: 17 DNFKLSSLANGLKVAT---SNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTE 73 + +L NGL+V + N G LY GSR E G H+L+ L FKST+ Sbjct: 6 PKHESVTLKNGLQVVSVPLENKTGVIEVDVLY-KVGSRNEVMGKSGIAHMLEHLNFKSTK 64 Query: 74 HVEGRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQ 133 +++ + ++ GG ++S + Y ++ K L+L +ET+ + E E Sbjct: 65 NLKAGEFDKIVKRFGGVSNASTSFDITRYFIKTSEANLDKSLELFAETMGSLNLKEDEFL 124 Query: 134 EQKLSAEYEIDEVWMKPELVLPELLHTAAYSGETLGSPL-ICPRELIPSISKYYLLD--- 189 ++ E W + +L+ ++ + P P + I + L D Sbjct: 125 PERQVVAEE--RRWRTDNSPIG-MLYFRFFNTAYVYHPYHWTPIGFMDDIQNWTLKDIKK 181 Query: 190 YRNKFYTPENTVAAFVG-VPHEKALELTEKYLGDWQSTHPPITKKVAQYTGGESCIPPAP 248 + + +Y P+N + VG V +K ELT+K+ ++ + A Sbjct: 182 FHSLYYQPKNAIVLVVGDVNSQKVFELTKKHFESLKNLDEKAIPTPYMKEPKQDGARTAV 241 Query: 249 VFGNLPELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLN 308 V + L + +G++ H D AL L LLG G S S L + +++ Sbjct: 242 VHKDGVHLEWVALGYKVPAFKHKDQVALDALSKLLGEGKS-----------SWLQSELVD 290 Query: 309 QYYFVENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVS 368 + + N D +F P +A++ + K +T+ E+ Sbjct: 291 KKRLASQAFSHNMQLQDESVFLFIAGGNPNIKAEALQKEIVALLEKL--KKGEITQAELD 348 Query: 369 RAKNQLKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIF 428 + K K+ + NLES ++ + L+ + + + DLK D+ RVA F Sbjct: 349 KIKINQKADFISNLESS-SDVAGLFADYLVQNDLQGLTDYQQQFLDLKVSDLVRVANEYF 407 Query: 429 TGNVN 433 + Sbjct: 408 KDTQS 412 >4NNZ-A nrPDB Length = 439 Score = 314 bits (804), Expect = 5e-86, Method: Composition-based stats. Identities = 90/436 (20%), Positives = 164/436 (37%), Gaps = 38/436 (8%) Query: 13 IARTDNFKLSSLANGLKVATSN---TPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAF 69 +A T SL NGLKV P S L I GS +E L G +H L+ + F Sbjct: 1 MAETQPTHEFSLDNGLKVIVREDHRAPVVVSQLWYRI--GSSYETPGLTGLSHALEHMMF 58 Query: 70 KSTEHVEGRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITE 129 K + + + L LG ++ + Y + + L++ ++ + + Sbjct: 59 KGSRKLGPGEASRVLRDLGAEENAFTTDDYTAYYQVLARDRLPVALEMEADRMAHLSLPV 118 Query: 130 QELQEQKLSAEYEID-EVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLL 188 + + + + E P + E AAY +P I + ++ L Sbjct: 119 DQFKSEIEVIKEERRLRTDDNPNALAFERFKAAAYPASGYHTPTIGWMADLQRMTIDDLR 178 Query: 189 DYRNKFYTPENTVAAFVG-VPHEKALELTEKYLGD--WQSTHPPITKKVAQYTGGESCIP 245 + +Y P N VG V ++ L ++Y G+ W+ PP K + GE + Sbjct: 179 HWYESWYAPNNATLVVVGDVTADEVKTLAKRYFGEIPWRQL-PPARKPLELAEPGERRL- 236 Query: 246 PAPVFGNLPELFHIQIGFE----GLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSR 301 V LP L +GF G + ++ AL + LL GG S + SR Sbjct: 237 KLYVRTQLPNLI---MGFNVPSLGSSENPREVNALRLIGALLDGGYS-------ARLASR 286 Query: 302 LYTHVLNQYYFVENCVAFNHSYSDSGIFGISLSCIPQA----APQAVEVIAQQMYNTFAN 357 L E VA +Y D+ G SL + + +E + ++ + Sbjct: 287 LERG--------EELVAGASTYYDAFNRGDSLFVLSATPNVQKGKTLEQVEAGLWKQLDD 338 Query: 358 -KDLRLTEDEVSRAKNQLKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLK 416 K + E+ R + Q+ + ++ +S + +G+ + +++ + ++ + Sbjct: 339 LKQNPPSAAEIERVRAQMIAGMVYEKDSIAAQASSIGQLESVGLSWKLIDQDLEALKAVT 398 Query: 417 PDDISRVAEMIFTGNV 432 PDDI + A FT + Sbjct: 399 PDDIQKAARTYFTPSR 414 >3CX5-B nrPDB Length = 352 Score = 170 bits (431), Expect = 9e-43, Method: Composition-based stats. Identities = 53/258 (20%), Positives = 102/258 (39%), Gaps = 13/258 (5%) Query: 28 LKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEGRAMAETLELL 87 L V+ + P S L + + GSR+ ++ G H+L+R F++T + ELL Sbjct: 1 LTVSARDAPTKISTLAVKVHGGSRYATKD--GVAHLLNRFNFQNTNTRSALKLVRESELL 58 Query: 88 GGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKL-SAEYEIDEV 146 GG ++ T RE + +A+ D+ + +++ + EL E L +A Y+ Sbjct: 59 GGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVA 118 Query: 147 WMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNKFYTPENTVAAFVG 206 P + L+ + + LG+PL+ + + +S + D+ +K YT EN + Sbjct: 119 EQCPVKSAEDQLYAITFR-KGLGNPLLY--DGVERVSLQDIKDFADKVYTKENLEVSGEN 175 Query: 207 VPHEKALELT-EKYLGDWQSTHPPITK-KVAQYTGGESCIPPAPVFGNLPELFHIQIGFE 264 V E L + ++K + + G E+ + + I I Sbjct: 176 VVEADLKRFVDESLLSTLPAGKSLVSKSEPKFFLGEENRVRFI-----GDSVAAIGIPVN 230 Query: 265 GLPIDHPDIYALATLQTL 282 + ++ A L Sbjct: 231 KASLAQYEVLANYLTSAL 248 >5CIO-A nrPDB Length = 793 Score = 87.2 bits (214), Expect = 2e-17, Method: Composition-based stats. Identities = 46/246 (18%), Positives = 87/246 (35%), Gaps = 11/246 (4%) Query: 23 SLANGLKVATSNTPGHFSALG-LYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEGRAMA 81 L NGL V +TPG +A + I+AGS G H+L+ + F+ + + + Sbjct: 31 QLDNGLAVRAISTPGAEAAAALVRIEAGSFQAPAAWPGLAHLLEHMLFRGSANFSAQDGL 90 Query: 82 ET-LELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKLSAE 140 + GG T+ + V + + L +S+ + P++ + + ++ + Sbjct: 91 MGWTQAAGGRLNATTQATQTAFFFEVGADPLAEGLARLSDMLAAPQLAAEAIAQEIEVID 150 Query: 141 YEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRE----LIPSISKYYLLDYRNKFYT 196 E + E + L I R I ++ + L + + +Y Sbjct: 151 AEYRLLRADGETRCEAAQRQMFSGFDALHRFHIGSRAAFGSDISALQQA-LRQFHHHYYR 209 Query: 197 PENTVAAFVGVPH-EKALELTEKYLGDW---QSTHPPITKKVAQYTGGESCIPPAPVFGN 252 N G E+ L ++Y G +T P +A +P AP Sbjct: 210 APNMTLWLQGPQSLEQLHALAQRYGGGLPSGSATPPETLPPLAAGQDYTLSLPGAPQLRL 269 Query: 253 LPELFH 258 + L H Sbjct: 270 VFTLPH 275 >1Q2L-A nrPDB Length = 939 Score = 83.3 bits (204), Expect = 2e-16, Method: Composition-based stats. Identities = 43/270 (15%), Positives = 102/270 (37%), Gaps = 12/270 (4%) Query: 5 GVQRLYSNIARTDN----FKLSSLANGLKVATSNTPGHFSAL-GLYIDAGSRFEGRNLKG 59 G Q + I ++D ++ L NG+ V + P +L L + GS + +G Sbjct: 3 GWQPIQETIRKSDKDNRQYQAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQG 62 Query: 60 CTHILDRLAFKSTEHVE-GRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLM 118 H L+ ++ ++ ++AE L++ GG++ +++ + V N + + + Sbjct: 63 LAHYLEHMSLMGSKKYPQADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRL 122 Query: 119 SETVRFPKITEQELQEQKLSAEYEIDEVW----MKPELVLPELLHTAAYSGETLGSPLIC 174 ++ + P + ++ + ++ + E+ M+ V E ++ A + G L Sbjct: 123 ADAIAEPLLDKKYAERERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLET 182 Query: 175 PRELIPSISKYYLLDYRNKFYTPENTVAAFVGVPHEKALELTEKYLGDWQSTHPPITKKV 234 + + + L D+ K+Y+ A ++ EL + + +KK Sbjct: 183 LSDKPGNPVQQALKDFHEKYYSANLMKAVI--YSNKPLPELAKMAADTFGRVPNKESKKP 240 Query: 235 AQYTGGESCIPPAPVFGNLPELFHIQIGFE 264 + + +P L + E Sbjct: 241 EITVPVVTDAQKGIIIHYVPALPRKVLRVE 270 >3GO9-A nrPDB Length = 492 Score = 71.0 bits (172), Expect = 9e-13, Method: Composition-based stats. Identities = 45/256 (17%), Positives = 81/256 (31%), Gaps = 20/256 (7%) Query: 17 DNFKLSSLANGLK---VATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTE 73 ++ L NG +AT P L L ++ GS E G H+L RLA S+ Sbjct: 24 PAWQQGKLDNGFSWQLLATPQRPSDRIELRLIVNTGSLSENTQEVGFAHLLPRLALMSSA 83 Query: 74 HVEGRAM----AETLELLGGNYQCTSSRENLMYQASV---FNQDVGKMLQLMSETVRFPK 126 + + ++ +S + +Y S+ + L +S+T Sbjct: 84 SFTPAQLQSLWQQGIDNERPLPPAITSYDFTLYSLSLPNNRPDLLKDALAWLSDTAGNLA 143 Query: 127 ITEQELQEQKLSAEYEIDEVWMKPELVLPEL-LHTAAYSGETLGSPLICPRELIPSISKY 185 ++EQ + +A I + L ++ G G P+ P + Sbjct: 144 VSEQTVNAALNTATDPIATFPQNIQEPWWRYRLKGSSLIGHDPGQPVTQPVD------VE 197 Query: 186 YLLDYRNKFYTPENTVAAFVG-VPHEKALELTEKYLGDWQS--THPPITKKVAQYTGGES 242 L + ++YTP+ VG V K + + T P +A Sbjct: 198 KLKQFYQQWYTPDAMTLYVVGNVDSRSIAAQISKAFSELKGKRTAPAAVATLAPLPPEPV 257 Query: 243 CIPPAPVFGNLPELFH 258 + + L Sbjct: 258 SLMNEQAAQDTLSLMW 273 >2FGE-A nrPDB Length = 995 Score = 62.2 bits (149), Expect = 5e-10, Method: Composition-based stats. Identities = 79/461 (17%), Positives = 148/461 (32%), Gaps = 60/461 (13%) Query: 27 GLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEGRAMAETLEL 86 G +V + + G+ R ++ G HIL + + +EL Sbjct: 46 GCEVMSVSNEDENKVFGVVF----RTPPKDSTGIPHILQHSVLCGSRKYPVKE--PFVEL 99 Query: 87 LGGNY----QCTSSRENLMYQASVFN-QDVGKMLQLMSETVRFPKI-------------- 127 L G+ + + Y + N +D ++ + + V FPK Sbjct: 100 LKGSLHTFLNAFTYPDRTCYPVASTNTKDFYNLVDVYLDAVFFPKCVDDAHTFQQEGWHY 159 Query: 128 ---TEQELQEQKLSAEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISK 184 E K E+ V+ +P+ +L + A T G + IP+++ Sbjct: 160 ELNDPSEDISYKGVVFNEMKGVYSQPDNILGRIAQQALSPENTYGVDSGGDPKDIPNLTF 219 Query: 185 YYLLDYRNKFYTPENTVAAFVGVPHEK-ALELTEKYLGDWQSTHPPIT---KKVAQYTGG 240 ++ ++Y P N F G L + +YL ++++ P + K ++ Sbjct: 220 EEFKEFHRQYYHPSNARIWFYGDDDPVHRLRVLSEYLDMFEASPSPNSSKIKFQKLFSEP 279 Query: 241 ESCIPPAPVFGNLP----ELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGK 296 + P + + + P+D AL L L+ G Sbjct: 280 VRLVEKYPAGRDGDLKKKHMLCVNWLLSEKPLDLQTQLALGFLDHLMLGTP--------- 330 Query: 297 GMYSRLYTHVLNQYYFVENCVAFNHSYSDSGI---FGISLSCIPQAAPQAVEVIAQQMYN 353 S L +L + E V+ S D + FGI L + + Q VE + Sbjct: 331 --ASPL-RKILLESGLGEALVSSGLS--DELLQPQFGIGLKGVSEENVQKVEELIMDTLK 385 Query: 354 TFANKDLRLTEDEVSRAKNQLKSSLLMNLESKLVELEDMGRQVLMHGRK----IPVNEMI 409 A + D V + N ++ SL N + Q + + Sbjct: 386 KLAEEGFD--NDAVEASMNTIEFSLRENNTGSFPRGLSLMLQSISKWIYDMDPFEPLKYT 443 Query: 410 SKIEDLKPDDISRVAEMIFTGNV-NNAGNGKGRATVVMQGD 449 ++ LK ++ +F+ + N R T+ MQ D Sbjct: 444 EPLKALKTRIAEEGSKAVFSPLIEKLILNNSHRVTIEMQPD 484 >1MX5-A nrPDB Length = 548 Score = 37.1 bits (84), Expect = 0.016, Method: Composition-based stats. Identities = 33/220 (15%), Positives = 62/220 (28%), Gaps = 18/220 (8%) Query: 161 AAYSGETLGSPLICPRELIPSISKYYLLDYRNK--FYTPENTVAAFVGVPHEKALELTEK 218 A + G P + P P + Y P + KA +L + Sbjct: 30 AIFLGIPFAKPPLGPLRFTPP-QPAEPWSFVKNATSYPP-------MCTQDPKAGQLLSE 81 Query: 219 YLGDWQSTHPPITKKVAQYTG--------GESCIPPAPVFGNLPELFHIQIGFEGLPIDH 270 + + P + Y ++ +P + ++GL + Sbjct: 82 LFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAA 141 Query: 271 PDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFVENCVAFNHSYSDSGIFG 330 + + T+Q LG G FS G V + +N +F + IFG Sbjct: 142 HENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFG 201 Query: 331 ISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRA 370 S + + + + + LT V + Sbjct: 202 ESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKG 241 >5JY4-B nrPDB Length = 391 Score = 33.7 bits (75), Expect = 0.19, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 23/67 (34%) Query: 215 LTEKYLGDWQSTHPPITKKVAQYTGGESCIPPAPVFGNLPELFHIQIGFEGLPIDHPDIY 274 L + K+V + E +P +P P L+H+ FEG + Sbjct: 233 LASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENAL 292 Query: 275 ALATLQT 281 LA L Sbjct: 293 TLACLLH 299 >3PDI-A nrPDB Length = 483 Score = 32.5 bits (72), Expect = 0.39, Method: Composition-based stats. Identities = 20/87 (22%), Positives = 34/87 (39%), Gaps = 16/87 (18%) Query: 384 SKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRV----------------AEMI 427 S + L+D+G +V+ G K E ++I +L DD+ + A+++ Sbjct: 346 SVVSALQDLGMKVVATGTKKSTEEDKARIRELMGDDVKMLDEGNARVLLKTVDEYQADIL 405 Query: 428 FTGNVNNAGNGKGRATVVMQGDRGSFG 454 G N KGR + FG Sbjct: 406 IAGGRNMYTALKGRVPFLDINQEREFG 432 >3LVY-A nrPDB Length = 207 Score = 31.7 bits (70), Expect = 0.70, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 22/74 (29%), Gaps = 6/74 (8%) Query: 167 TLGSPLICPRELIPSISKYYLLDYRNKFYTPENTVAAFVGVPHEKALELTEKYLGDWQST 226 TL I + D+ YTPEN + +GV Sbjct: 139 TLAKFTIAVINTKGRVGDEAFADFLEVGYTPENALDVVLGVSLASLCNYANNM------A 192 Query: 227 HPPITKKVAQYTGG 240 PI ++ QY G Sbjct: 193 DTPINPELQQYVKG 206 >1YXA-A nrPDB Length = 398 Score = 31.7 bits (70), Expect = 0.79, Method: Composition-based stats. Identities = 32/158 (20%), Positives = 54/158 (34%), Gaps = 14/158 (8%) Query: 43 GLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEGRAMAETLELLGGNYQCTSSRENLMY 102 GL + E +G H+L RL + A +E + +Y Sbjct: 80 GLKFNLTETSEADIHQGFGHLLQRLNQPKDQVQISTGSALFIEKRQQILTEFQEKAKTLY 139 Query: 103 QASVFNQDVG---KMLQLMSETVRFPK---ITE--QELQEQKLSAEYEI---DEVWMKPE 151 QA F D + +L+++ VR I E +L ++ L W P Sbjct: 140 QAEAFTADFQQPRQAKKLINDYVRKQTQGMIKELVSDLDKRTLMVLVNYIYFKAKWKVPF 199 Query: 152 LVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLD 189 L + + Y G+ P+I P + ++ Y D Sbjct: 200 DPL-DTFKSEFYCGK--RRPVIVPMMSMEDLTTPYFRD 234 >5DYK-A nrPDB Length = 853 Score = 31.0 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 25/104 (24%), Positives = 40/104 (38%), Gaps = 7/104 (6%) Query: 372 NQLKSSLLMNLESKL-VELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFTG 430 Q ++++ + L R L NE + I+ + D+ A+ Sbjct: 130 TQRSATIIAETDGTLWGVQRSTFRATLKQLSNRNFNENRTFIDSVSVFDMLTEAQKNMIT 189 Query: 431 NVNNAGNGKGRATVVMQGDRGSFGDVENVLKAYGLGNSSSSKND 474 N N K T+V QGD +GDV +LK G ++ ND Sbjct: 190 NACVIQNFKSGETIVKQGD---YGDVLYILKE---GKATVYIND 227 >5FET-A nrPDB Length = 847 Score = 28.6 bits (62), Expect = 5.5, Method: Composition-based stats. Identities = 22/91 (24%), Positives = 34/91 (37%), Gaps = 4/91 (4%) Query: 372 NQLKSSLLMNLESKL-VELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFTG 430 Q ++++ + L R L NE S I+ + D+ A+ Sbjct: 124 TQRSATIMAETDGTLWGVQRSTFRATLKQLSNRNFNENRSFIDSVSVFDMLTEAQKNMIT 183 Query: 431 NVNNAGNGKGRATVVMQGDRGSFGDVENVLK 461 N K T+V QGD +GDV +LK Sbjct: 184 NACVIQMFKPGETIVKQGD---YGDVLFILK 211 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.304 0.121 0.278 Lambda K H 0.267 0.0373 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,840,546 Number of Sequences: 36641 Number of extensions: 556464 Number of successful extensions: 1665 Number of sequences better than 10.0: 29 Number of HSP's better than 10.0 without gapping: 47 Number of HSP's successfully gapped in prelim test: 13 Number of HSP's that attempted gapping in prelim test: 1502 Number of HSP's gapped (non-prelim): 61 length of query: 482 length of database: 10,336,785 effective HSP length: 101 effective length of query: 381 effective length of database: 6,636,044 effective search space: 2528332764 effective search space used: 2528332764 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.0 bits) S2: 61 (28.2 bits)