BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P11880 (452 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1GG4-A nrPDB 915 0.0 4CVK-A nrPDB 328 3e-90 4QDI-A nrPDB 295 3e-80 3ZM5-A nrPDB 164 9e-41 3ZL8-A nrPDB 157 9e-39 4BUB-A nrPDB 94 1e-19 4C12-A nrPDB 89 3e-18 3LK7-A nrPDB 57 1e-08 5VVW-A nrPDB 57 2e-08 1GQY-A nrPDB 56 4e-08 6CAU-A nrPDB 55 4e-08 4BUC-A nrPDB 54 1e-07 2WTZ-A nrPDB 48 9e-06 3EAG-A nrPDB 44 2e-04 2JFH-A nrPDB 40 0.002 2VOR-A nrPDB 39 0.005 3HN7-A nrPDB 37 0.015 4HV4-A nrPDB 37 0.018 2F00-A nrPDB 35 0.079 1E8C-A nrPDB 34 0.12 1J6U-A nrPDB 34 0.13 6FQB-A nrPDB 33 0.17 6H5E-B nrPDB 32 0.71 2DY0-A nrPDB 28 5.8 4TSK-A nrPDB 28 6.4 5NEJ-1 nrPDB 28 6.9 1Y3F-E nrPDB 28 8.1 >1GG4-A nrPDB Length = 452 Score = 915 bits (2366), Expect = 0.0, Method: Compositional matrix adjust. Identities = 452/452 (100%), Positives = 452/452 (100%) Query: 1 MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAG 60 MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAG Sbjct: 1 MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAG 60 Query: 61 GAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA 120 GAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA Sbjct: 61 GAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA 120 Query: 121 ILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAAL 180 ILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAAL Sbjct: 121 ILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAAL 180 Query: 181 VNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFS 240 VNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFS Sbjct: 181 VNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFS 240 Query: 241 PNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATL 300 PNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATL Sbjct: 241 PNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATL 300 Query: 301 DAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGD 360 DAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGD Sbjct: 301 DAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGD 360 Query: 361 MAELGAESEACHVQVGEAAKAAGIDRVLSVGKQSHAISTASGVGEHFADKTALITRLKLL 420 MAELGAESEACHVQVGEAAKAAGIDRVLSVGKQSHAISTASGVGEHFADKTALITRLKLL Sbjct: 361 MAELGAESEACHVQVGEAAKAAGIDRVLSVGKQSHAISTASGVGEHFADKTALITRLKLL 420 Query: 421 IAEQQVITILVKGSRSAAMEEVVRALQENGTC 452 IAEQQVITILVKGSRSAAMEEVVRALQENGTC Sbjct: 421 IAEQQVITILVKGSRSAAMEEVVRALQENGTC 452 >4CVK-A nrPDB Length = 475 Score = 328 bits (841), Expect = 3e-90, Method: Compositional matrix adjust. Identities = 211/449 (46%), Positives = 278/449 (61%), Gaps = 13/449 (2%) Query: 6 LSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAGGAGAL 65 LSQLT L+ L G D AV+TD+R + PG LF+AL G RFD HD+ + A GA A Sbjct: 7 LSQLTVALDARLIGEDAVFSAVSTDSRAIGPGELFIALSGPRFDGHDYLAEVAAKGAVAA 66 Query: 66 LVSRPL-DIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAAIL-S 123 LV R + D LPQL+V+DTR A G L A R++ + A+TGSSGKT+VKEM A+IL + Sbjct: 67 LVEREVADAPLPQLLVRDTRAALGRLGALNRRKFTGPLAAMTGSSGKTTVKEMLASILRT 126 Query: 124 QCGN---TLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAAL 180 Q G+ L T GNLNND+GVP+TLL+L P++ AVIELGA+ GEIA+TV LTRP A+ Sbjct: 127 QAGDAESVLATRGNLNNDLGVPLTLLQLAPQHRSAVIELGASRIGEIAYTVELTRPHVAI 186 Query: 181 VNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFS 240 + N AH+ FG + +AKGEI GL +G A++N D+ + W++ R + FS Sbjct: 187 ITNAGTAHVGEFGGPEKIVEAKGEILEGLAADGTAVLNLDDKAFDTWKARASGRPLLTFS 246 Query: 241 PNAANSDFTATNIHVTSHGTE-FTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGAT 299 + +DF A ++ + G F LQ G V L L GRHN+ANALAAAA + ++G Sbjct: 247 LDRPQADFRAADLQRDARGCMGFRLQGVAGEAQVQLNLLGRHNVANALAAAAAAHALGVP 306 Query: 300 LDAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVG 359 LD I AGL L+ V GR A ++DDSYNAN SM AA+ +L+ G VLV+G Sbjct: 307 LDGIVAGLQALQPVKGRAVAQLTASGLRVIDDSYNANPASMLAAIDILSGFSGRTVLVLG 366 Query: 360 DMAELGAESEACHVQVGEAAKAAG-IDRVLSVGK-QSHAISTASGVGEHFADKTALITRL 417 DM ELG+ +E H +VG A AAG + + +VG +HA+ G HFAD+ +LI L Sbjct: 367 DMGELGSWAEQAHREVG--AYAAGKVSALYAVGPLMAHAVQAFGATGRHFADQASLIGAL 424 Query: 418 KLLIAEQQVITILVKGSRSAAMEEVVRAL 446 E TIL+KGSRSAAM++VV AL Sbjct: 425 A---TEDPTTTILIKGSRSAAMDKVVAAL 450 >4QDI-A nrPDB Length = 472 Score = 295 bits (755), Expect = 3e-80, Method: Compositional matrix adjust. Identities = 180/432 (41%), Positives = 246/432 (56%), Gaps = 15/432 (3%) Query: 27 VTTDTRKLTPGCLFVALKGERFDAHDFADQAKAGGAGALLVSRPLDIDLPQLIVKDTRLA 86 + TD+R G F+ALKGERFDAH+F Q A G +V RP+D ++ QL+V DTRLA Sbjct: 46 ILTDSRHAESGDAFLALKGERFDAHNFVAQVVANGCQVAIVERPIDAEIAQLVVADTRLA 105 Query: 87 FGELAAWVRQQ-VPARVVALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIGVPMTL 145 G+L A+ R+Q +V+ALTGSSGKT+ KEM +ILS+ TL T GNLNND+GVPM L Sbjct: 106 LGQLGAYRREQNAQLKVIALTGSSGKTTTKEMLGSILSRLAPTLITRGNLNNDLGVPMML 165 Query: 146 LRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEI 205 L L E+ YAV+ELGANHQGEI +T + +P A + N+ AHL FG G+ +AK EI Sbjct: 166 LELRKEHQYAVMELGANHQGEIDYTSKIVQPHVAGILNIGTAHLGEFGGRDGICRAKSEI 225 Query: 206 FSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQ 265 + + G+AI+ ++ + S ++ F D AT I + F L Sbjct: 226 YRHILPQGVAIVPQQDDFTAEIREAAKSHQIMSF---GEGGDVFATEIELLPQSANFQLH 282 Query: 266 TPTGSVDVLLPLPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPIQLAEN 325 TP GS V LP G HN+ NA AA A ++++G +L+ I GL + GRL IQ A + Sbjct: 283 TPQGSSFVRLPFAGEHNVQNATAAVAFALALGVSLEDIVKGLEQAQGAKGRLNFIQKAPH 342 Query: 326 QLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGDMAELGAESEACHVQVGEAAKAAGID 385 L +DD+YNAN SM AA QVL + G +V+V+GD+ ELG S H +G +D Sbjct: 343 -LFIDDTYNANPTSMRAAAQVLLQQNGIKVMVMGDIGELGDSSWQEHHDLGRDLAELPLD 401 Query: 386 RVLSVGKQSHAISTASGVGEHFADKTALITR---LKLLI-----AEQQVITILVKGSRSA 437 +++VG+ A + G G H A T+ L LI + Q ++ L KGSR Sbjct: 402 HIVAVGQ--FASAALEGAGLHSTKLKAFQTQAEALPFLINLIQTHQPQSMSFLFKGSRFT 459 Query: 438 AMEEVVRALQEN 449 ME ++ L E Sbjct: 460 HMETLMADLMEK 471 >3ZM5-A nrPDB Length = 465 Score = 164 bits (414), Expect = 9e-41, Method: Compositional matrix adjust. Identities = 129/443 (29%), Positives = 216/443 (48%), Gaps = 28/443 (6%) Query: 21 DITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAGGAGALLVSRPLDIDLPQLIV 80 D L+ D+R + G LFV LKG R D HDF + A GA L + + + P ++V Sbjct: 23 DTQLEKAEFDSRLIGTGDLFVPLKGAR-DGHDFIETAFENGAAVTLSEKEVS-NHPYILV 80 Query: 81 KDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIG 140 D AF LA++ ++ V A+TGS+GKT+ K+M A +LS T T GN NN+IG Sbjct: 81 DDVLTAFQSLASYYLEKTTVDVFAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIG 140 Query: 141 VPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAK 200 +P T+L + + V+E+G +H G+I L RP+ A+V + AHL F + +AK Sbjct: 141 LPYTVLHMPEGTEKLVLEMGQDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAK 200 Query: 201 AKGEIFSGLPENGIAIMNADN--NDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSH 258 K +I G+ + + AD D+L +KV RF A + T++ Sbjct: 201 GKMQIADGMASGSLLLAPADPIVEDYLPI-----DKKVVRFGQGA---ELEITDLVERKD 252 Query: 259 GTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLF 318 F ++D LP+ G++N NA+ A+ +++ G + + I+ +L+ R Sbjct: 253 SLTFKANFLEQALD--LPVTGKYNATNAMIASYVALQEGVSEEQIRLAFQHLELTRNRTE 310 Query: 319 PIQLAENQLLLDDSYNANVGSMTAAVQVLAEMP----GYRVLVVGDMAELGAESEACHVQ 374 + A +L D YNAN +M ++ + +P G ++ V+ DM ELG +S H Q Sbjct: 311 WKKAANGADILSDVYNANPTAMKLILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQ 370 Query: 375 VGEAAKAAGIDRVLSVGKQ----SHAISTASGVGE-HFADKTALITRLKLLIAEQQVI-- 427 + + +D V+ G+ + S +G ++ KT + + L+ + + Sbjct: 371 MILSLSPDVLDIVIFYGEDIAQLAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLG 430 Query: 428 ---TILVKGSRSAAMEEVVRALQ 447 IL+KGS S + ++V +L+ Sbjct: 431 AHDQILLKGSNSMNLAKLVESLE 453 >3ZL8-A nrPDB Length = 437 Score = 157 bits (397), Expect = 9e-39, Method: Compositional matrix adjust. Identities = 129/438 (29%), Positives = 209/438 (47%), Gaps = 29/438 (6%) Query: 21 DITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAGGAGALLVSRPLDIDLPQLIV 80 D+ +++++ G +FVA+KG+RFD HDF D+A GA A++ R +V Sbjct: 3 DLLTRRFVLNSKEVREGDVFVAVKGKRFDGHDFIDEALRNGAYAIIAERKTVNSDRIFLV 62 Query: 81 KDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIG 140 + + +LA VV +TGSSGKT+ KE+ +L + T GN+N + G Sbjct: 63 ESSVDTLAKLAREKLGNFSGTVVGVTGSSGKTTTKEILYNLLKNKRSVFKTPGNMNTEYG 122 Query: 141 VPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAK 200 +P+++L + V+E+ A+ G+IA + P+ A++ N+ +AHLE FG+ + + Sbjct: 123 LPLSILNDYKGEEILVLEMAASRPGDIAHLCKIAPPDVAVLLNVGSAHLEFFGTRERIME 182 Query: 201 AKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGT 260 K EI EN IA+ D+ D + V R F +S + S Sbjct: 183 TKMEIIKHSKENAIAVTLFDDPDLR--KEVPRYRNTLFFGKEGGDSVLKDWWYYEGSTIA 240 Query: 261 EFTLQTPTGSVDVLL--PLPGRHN---IANALAAAALSMSVGATLDAIKAGLANLKAVPG 315 EF + D L L G N + N A+ + ++G T+D LA+LK VPG Sbjct: 241 EFE------AFDSLFTVKLSGYWNGGQLLNIAASLCVMRTLGETVDIF--DLASLKTVPG 292 Query: 316 RLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGDMAELGAESEACHVQV 375 R F ++ + L++DD+YNA+ + +++ L PG + VVG M ELG S+ H ++ Sbjct: 293 R-FNVREKKGVLIVDDTYNASPEAFQTSIEALLRFPGKKFAVVGAMKELGERSKEFHEEL 351 Query: 376 GEAAKAA-GIDRVLSVGK----QSHAISTASGVGEHFADKTALITRLKLLIAEQQVITIL 430 GE G+ LS + +S I S E A A TR+K + +L Sbjct: 352 GERLNVLDGVYVFLSEPEAEWIKSKKIILKSDDPEKIAKDLA--TRVK------KGDVVL 403 Query: 431 VKGSRSAAMEEVVRALQE 448 K SR+ +E V+ ++ Sbjct: 404 FKASRAVRIERVLEMFEK 421 >4BUB-A nrPDB Length = 498 Score = 94.4 bits (233), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 86/338 (25%), Positives = 147/338 (43%), Gaps = 34/338 (10%) Query: 2 ISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAGG 61 IS +S L D++ D+ + V+ + K+ G LF+ +GE+FD+H+ + G Sbjct: 3 ISTIVSNLKDLILEVRAPYDLEITGVSNHSSKVKKGDLFICRRGEKFDSHEIIPEVMEKG 62 Query: 62 AGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGK---------- 111 A A++V R +D+D P + V D+R ++A+ + V+ + Sbjct: 63 AVAVVVEREIDLDFPYIQVFDSRYFEAKVASLFFEDPWKDVLTFGVTGTNGKTTTTMMIY 122 Query: 112 ---TSVKE----MTAAILSQCGNTLYTAGNLNNDIGVP-----MTLLRLTPEYDYAVIEL 159 TS+ E +T A+ GN+ Y +DI P ++ ++ E L Sbjct: 123 HMLTSLGERGSVLTTAVKRILGNSYY------DDITTPDAITILSAMKENREGGGKFFAL 176 Query: 160 GANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNA 219 + + V R + + N++ HL+ G+ KAK +F L ++G+A++N Sbjct: 177 EVSSHALVQQRVEGVRFDVGIFTNISRDHLDFHGTFENYLKAKLHLFDLLKDDGVAVLNE 236 Query: 220 DNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPG 279 D N + SRK+ + N+D+ NI V+ GT+F L+TP G + V G Sbjct: 237 SLADAFNRK----SRKIT--FGTSKNADYRLGNIEVSWEGTQFVLETPDGLLKVFTRAIG 290 Query: 280 RHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRL 317 N NA AA A +G + + L V GR Sbjct: 291 DFNAYNAAAAIAALHQLGYDPKDLASSLETFTGVEGRF 328 >4C12-A nrPDB Length = 501 Score = 89.4 bits (220), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 86/318 (27%), Positives = 142/318 (44%), Gaps = 28/318 (8%) Query: 24 LDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAGGAGALLVSRP--LDIDLPQLIVK 81 +D +TTD+R G +FVA G D+H F G ++V++ L ++ Q++V Sbjct: 23 IDDITTDSRTAREGSIFVASVGYTVDSHKFCQNVADQGCKLVVVNKEQSLPANVTQVVVP 82 Query: 82 DTRLAFGELAAWVRQQVPAR---VVALTGSSGKTSVKEMTAAI---LSQCGNTLYTAGNL 135 DT L + A P+ +TG++GKTS+ M I L + L T G Sbjct: 83 DT-LRVASILAHTLYDYPSHQLVTFGVTGTNGKTSIATMIHLIQRKLQKNSAYLGTNGFQ 141 Query: 136 NNDIGV------PMTLLRLTPEYDYAV------IELGANHQGEIAWTVSLTRPEAALVNN 183 N+ P T+ LT + AV + L + G + + + A+ +N Sbjct: 142 INETKTKGANTTPETV-SLTKKIKEAVDAGAESMTLEVSSHGLVLGRLRGVEFDVAIFSN 200 Query: 184 LAAAHLEGFGSLAGVAKAKGEIFSGLPEN----GIAIMNADNNDWLNWQSVIGSRKVWRF 239 L HL+ G++ AK +FS L E+ ++N D++ + + + +V+ + Sbjct: 201 LTQDHLDFHGTMEAYGHAKSLLFSQLGEDLSKEKYVVLNNDDS-FSEYLRTVTPYEVFSY 259 Query: 240 SPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGAT 299 + + F A NI + G F TP G+ V P G+ NI+N +AA S G + Sbjct: 260 GIDE-EAQFMAKNIQESLQGVSFDFVTPFGTYPVKSPYVGKFNISNIMAAMIAVWSKGTS 318 Query: 300 LDAIKAGLANLKAVPGRL 317 L+ I + NL+ V GRL Sbjct: 319 LETIIKAVENLEPVEGRL 336 >3LK7-A nrPDB Length = 451 Score = 57.4 bits (137), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 66/253 (26%), Positives = 109/253 (43%), Gaps = 26/253 (10%) Query: 89 ELAAWVRQQVPARVVALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIGVPMT-LLR 147 ELA V + ++++ +TGS+GKT+ M A +L+ G AGN IG P + +++ Sbjct: 104 ELAYLVSE---SQLIGITGSNGKTTTTTMIAEVLNAGGQRGLLAGN----IGFPASEVVQ 156 Query: 148 LTPEYDYAVIELGANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFS 207 + D V+EL + V RP A++ NL HL+ GS AK I + Sbjct: 157 AANDKDTLVMELSSFQ----LMGVKEFRPHIAVITNLMPTHLDYHGSFEDYVAAKWNIQN 212 Query: 208 GLPENGIAIMNADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTE---FTL 264 + + ++N + G K + A F+ T ++ + F Sbjct: 213 QMSSSDFLVLNFNQ----------GISKELAKTTKATIVPFSTTEKVDGAYVQDKQLFYK 262 Query: 265 QTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPIQLAE 324 SVD + +PG HN+ NALA A++ G + I+ L+N V RL + Sbjct: 263 GENIMSVDD-IGVPGSHNVENALATIAVAKLAGISNQVIRETLSNFGGVKHRLQSLGKVH 321 Query: 325 NQLLLDDSYNANV 337 +DS + N+ Sbjct: 322 GISFYNDSKSTNI 334 >5VVW-A nrPDB Length = 315 Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 78/313 (24%), Positives = 129/313 (41%), Gaps = 42/313 (13%) Query: 13 LNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAGGAGALLVSRPLD 72 L E+ G+D+ AVT K +F+ + E D GA L+VS ++ Sbjct: 31 LGYEVSGSDLKASAVTERLEKFG-AQIFIGHQAENAD-----------GADVLVVSSAIN 78 Query: 73 IDLPQLIVK-DTRLAFGELAAWVRQQVPARV-VALTGSSGKTSVKEMTAAILSQCG--NT 128 P++ + R+ A + + + R +A+ G+ GKT+ + A++ + G T Sbjct: 79 RANPEVASALERRIPVVPRAEMLAELMRYRHGIAVAGTHGKTTTTSLIASVFAAGGLDPT 138 Query: 129 LYTAGNLNN-----DIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAALVNN 183 G LN +G L+ E D + + L +P A+V N Sbjct: 139 FVIGGRLNAAGTNAQLGASRYLVAEADESDASFLHL---------------QPMVAVVTN 183 Query: 184 LAAAHLEGFG-SLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKV-WRFSP 241 + A H+ +G + K E LP G+A+M D+ I V + S Sbjct: 184 IDADHMATYGGDFNKLKKTFVEFLHNLPFYGLAVMCVDDPVVREILPQIARPTVTYGLSE 243 Query: 242 NAANSDFTATNIHVTSHGTEFTLQTPTGS-VDVLLPLPGRHNIANALAAAALSMSVGATL 300 +A D A NI T FT+ P +DV + +PG HN+ N+LA ++ G + Sbjct: 244 DA---DVRAINIRQEGMRTWFTVLRPEREPLDVSVNMPGLHNVLNSLATIVIATDEGISD 300 Query: 301 DAIKAGLANLKAV 313 +AI GL+ + V Sbjct: 301 EAIVQGLSGFQGV 313 >1GQY-A nrPDB Length = 475 Score = 55.8 bits (133), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 71/277 (25%), Positives = 123/277 (44%), Gaps = 34/277 (12%) Query: 61 GAGALLVSRPLDIDLPQLIV-KDTRLAFGELAAWVRQQVPARV-VALTGSSGKTSVKEMT 118 GA ++VS + D P+L+ K R+ + A + + + R +A+ G+ GKT+ M Sbjct: 77 GASVVVVSSAIKDDNPELVTSKQKRIPVIQRAQMLAEIMRFRHGIAVAGTHGKTTTTAMI 136 Query: 119 AAILSQC--------GNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWT 170 + I +Q G + +AG N +G L+ E D + + L Sbjct: 137 SMIYTQAKLDPTFVNGGLVKSAGK-NAHLGASRYLIAEADESDASFLHL----------- 184 Query: 171 VSLTRPEAALVNNLAAAHLEGF-GSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQS 229 +P ++V N+ H++ + G + + LP G+A+M AD+ + Sbjct: 185 ----QPMVSVVTNMEPDHMDTYEGDFEKMKATYVKFLHNLPFYGLAVMCADDPVLMELVP 240 Query: 230 VIGSRKV-WRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGS-VDVLLPLPGRHNIANAL 287 +G + + + FS A D+ + T +T+ P ++VLL +PG+HN NA Sbjct: 241 KVGRQVITYGFSEQA---DYRIEDYEQTGFQGHYTVICPNNERINVLLNVPGKHNALNAT 297 Query: 288 AAAALSMSVGATLDAIKAGLANLKAVPGRLFPIQLAE 324 AA A++ G +AI LA+ + GR F QL E Sbjct: 298 AALAVAKEEGIANEAILEALADFQGA-GRRFD-QLGE 332 >6CAU-A nrPDB Length = 472 Score = 55.5 bits (132), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 51/190 (26%), Positives = 86/190 (45%), Gaps = 9/190 (4%) Query: 175 RPEAALVNNLAAAHLEGF-GSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGS 233 +P AA+V N+ A H++ + GS + + LP G+A++ D+ + +G Sbjct: 179 QPMAAIVTNIDADHMDTYEGSFDKLKDTFVQFLHNLPFYGLAVVCGDDANIREILPRVG- 237 Query: 234 RKVWRFSPNAANSDFTATNIHVTSHGTEFT-LQTPTGSVDVLLPLPGRHNIANALAAAAL 292 R V + N N D A ++ + FT L+ + + + PG HN+ NALAA + Sbjct: 238 RPVITYGFNEDN-DIRAIDVEQDGMRSHFTVLRKGREPLRLTINQPGLHNVLNALAAIGV 296 Query: 293 SMSVGATLDAIKAGLANLKAVPGRLFPIQ----LAENQLLLDDSYNANVGSMTAAVQVLA 348 + G + +AI L V GR F +Q L E + L D Y + + A ++ Sbjct: 297 ATDEGVSDEAISRALKGFSGV-GRRFQVQGEFELGEGNVKLVDDYGHHPKEVEATIKAAR 355 Query: 349 EMPGYRVLVV 358 + R LV+ Sbjct: 356 QSHPDRRLVM 365 >4BUC-A nrPDB Length = 450 Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 63/246 (25%), Positives = 106/246 (43%), Gaps = 29/246 (11%) Query: 89 ELAAWVRQQVPARVVALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIGVPMTLLRL 148 EL ++ P +VV +TG+ GK++ + +LS G + GN G P + L Sbjct: 111 ELQFFLDNVDPKKVVGITGTDGKSTATALMYHVLSGRGFKTFLGGNF----GTP-AVEAL 165 Query: 149 TPEYDYAVIELGANHQGEIAWTVSLTRPEAA--LVNNLAAAHLEGFGSLAGVAKAKGEIF 206 EYDY V+E+ + ++ W+ RP + LV N++ HL+ S +K + Sbjct: 166 EGEYDYYVLEMSSF---QLFWS---ERPYLSNFLVLNISEDHLDWHSSFKEYVDSKLKPA 219 Query: 207 SGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQT 266 E + + N N + V SRK+ P + +F AT + G ++TL Sbjct: 220 FLQTEGDLFVYNKHIERLRNLEGV-RSRKI----PFWTDENF-ATEKELIVRGKKYTL-- 271 Query: 267 PTGSVDVLLPLPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPIQLAENQ 326 P P R NI LA + L M + L++ L + K +P R+ + + + Sbjct: 272 PGN-----YPYQMRENI---LAVSVLYMEMFNELESFLELLRDFKPLPHRMEYLGQIDGR 323 Query: 327 LLLDDS 332 +DS Sbjct: 324 HFYNDS 329 >2WTZ-A nrPDB Length = 535 Score = 47.8 bits (112), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 109/397 (27%), Positives = 166/397 (41%), Gaps = 49/397 (12%) Query: 1 MISVTLSQLTD-----ILNGELQGA---DITLDAVTTDTRKLTPGCLFVALKGERFDAHD 52 ++ V L+ L D + G Q A D T+ VT + ++PG LF AL G Sbjct: 31 VVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALTGSTTHGAR 90 Query: 53 FADQAKAGGAGALLVSRPLDID-------LPQLIVKDTRLAFGELAAWVRQQVPAR--VV 103 A A GA A+L P + +P L+ R G LAA V R V+ Sbjct: 91 HVGDAIARGAVAVLTD-PAGVAEIAGRAAVPVLVHPAPRGVLGGLAATVYGHPSERLTVI 149 Query: 104 ALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIG---VPMTLLRLTPE--------- 151 +TG+SGKT+ + A L G G + +G +P L TPE Sbjct: 150 GITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALT--TPEAPTLQAMLA 207 Query: 152 ------YDYAVIELGANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEI 205 D V+E+ ++H + V TR NL+ HL+ S+A +AK + Sbjct: 208 AMVERGVDTVVMEV-SSHALALGR-VDGTRFAVGAFTNLSRDHLDFHPSMADYFEAKASL 265 Query: 206 FSGLPENGIAIMNADN--NDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVT-SHGTEF 262 F P++ + A +D + S + + AT++ T + G +F Sbjct: 266 FD--PDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQQF 323 Query: 263 TLQTPTG-SVDVLLPLPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPIQ 321 T P G + + LPGR+N+AN L A A+ +VG + + GL ++ VPGRL I Sbjct: 324 TAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIR-VPGRLEQID 382 Query: 322 LAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVV 358 + L L D Y ++ + + LA P R+ VV Sbjct: 383 RGQGFLALVD-YAHKPEALRSVLTTLAH-PDRRLAVV 417 >3EAG-A nrPDB Length = 326 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 58/231 (25%), Positives = 82/231 (35%), Gaps = 35/231 (15%) Query: 102 VVALTGSSGKTSVKEMTAAILSQCG-NTLYTAGNLNNDIGVPMTLLRLTPEYD------Y 154 V+ + G+ GKT+ M A +L G + G + + GV L + TP D + Sbjct: 110 VLGVAGTHGKTTTASMLAWVLEYAGLAPGFLIGGVPENFGVSARLPQ-TPRQDPNSQSPF 168 Query: 155 AVIELGANHQGEIAWTVSLT--RPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPEN 212 VIE RP A++NNL H + F L + + +P Sbjct: 169 FVIEADEYDTAFFDKRSKFVHYRPRTAVLNNLEFDHADIFADLGAIQTQFHYLVRTVPSE 228 Query: 213 GIAIMNADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVD 272 G+ + N + Q + + W T T HG + GS D Sbjct: 229 GLIVCNGRQQ---SLQDTL-DKGCW-----------TPVEKFGTEHGWQAGEANADGSFD 273 Query: 273 VLL----------PLPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAV 313 VLL L GRHN NALA A + VG + L K V Sbjct: 274 VLLDGKTAGRVKWDLMGRHNRMNALAVIAAARHVGVDIQTACEALGAFKNV 324 >2JFH-A nrPDB Length = 445 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 79/279 (28%), Positives = 125/279 (44%), Gaps = 31/279 (11%) Query: 88 GELAAWVRQ-QVPARVVALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIGVPMTLL 146 G++ + R+ Q P +VA+TGS+GK++V + + G + GN IG+P +L Sbjct: 94 GDIELFCREAQAP--IVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGN----IGLPALML 147 Query: 147 RLTPEYDYAVIELGANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFG-SLAGVAKAKGEI 205 L E + V+EL ++ Q E T S + AA + N+ H++ + L AK I Sbjct: 148 -LDDECELYVLEL-SSFQLE---TTSSLQAVAATILNVTEDHMDRYPFGLQQYRAAKLRI 202 Query: 206 FSGLPENG-IAIMNADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTL 264 + EN + ++NAD D L + F N + H+ E L Sbjct: 203 Y----ENAKVCVVNAD--DALTMPIRGADERCVSFGVNMGD-------YHLNHQQGETWL 249 Query: 265 QTPTGSVDVL--LPLPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPIQL 322 + V + + L G+HN NALAA AL+ + G + L +P R F + L Sbjct: 250 RVKGEKVLNVKEMKLSGQHNYTNALAALALADAAGLPRASSLKALTTFTGLPHR-FEVVL 308 Query: 323 AENQL-LLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGD 360 N + ++DS NVGS AA+ L +L+ GD Sbjct: 309 EHNGVRWINDSKATNVGSTEAALNGLHVDGTLHLLLGGD 347 >2VOR-A nrPDB Length = 487 Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust. Identities = 59/221 (26%), Positives = 99/221 (44%), Gaps = 29/221 (13%) Query: 153 DYAVIELGANHQGEIAWTVS-LTRPEAALVNNLAAAHLEGFGS-LAGVAKAKGEIFSGLP 210 D AV+E+G + W + + A++ ++ H++ G+ +AG+A K I + P Sbjct: 169 DVAVVEVGMGGR----WDATNVINAPVAVITPISIDHVDYLGADIAGIAGEKAGIITRAP 224 Query: 211 E---NGIAIMNADNN---DWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTL 264 + + +A++ + L +SV V R +S+F + G L Sbjct: 225 DGSPDTVAVIGRQVPKVMEVLLAESVRADASVAR-----EDSEFAVLRRQIAVGGQVLQL 279 Query: 265 QTPTGSV-DVLLPLPGRHNIANA-LAAAALSMSVGATL------DAIKAGLANLKAVPGR 316 Q G D+ LPL G H NA LA A++ GA DA++AG A + + PGR Sbjct: 280 QGLGGVYSDIYLPLHGEHQAHNAVLALASVEAFFGAGAQRQLDGDAVRAGFAAVTS-PGR 338 Query: 317 LFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLV 357 L ++ A + +D ++N +A Q LA +R LV Sbjct: 339 LERMRSAPT-VFIDAAHNP--AGASALAQTLAHEFDFRFLV 376 >3HN7-A nrPDB Length = 524 Score = 37.4 bits (85), Expect = 0.015, Method: Compositional matrix adjust. Identities = 43/182 (23%), Positives = 73/182 (40%), Gaps = 30/182 (16%) Query: 175 RPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGS- 233 RP A++NNL H + F L + + +P G IM A ++ + + Sbjct: 216 RPRTAILNNLEFDHADIFADLDAIQTQFHHMVRMIPSTGKIIMPAAT---ISLEDTLAKG 272 Query: 234 --RKVWRFS------------------PNAANS-DFTATNIHVTSHGTEFTL---QTPTG 269 +WR S A NS D+ A I ++ G++FT+ Sbjct: 273 VWTPIWRTSVIDSTISSVRREDSPLENSQAENSSDWQAELI--SADGSQFTVSFNDNKEA 330 Query: 270 SVDVLLPLPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPIQLAENQLLL 329 + V + G HN+ NAL A A + ++G ++ A L+ + R+ I + L+ Sbjct: 331 TALVNWSMSGLHNVNNALVAIAAAYNIGVSVKTACAALSAFAGIKRRMELIGDVNDILVF 390 Query: 330 DD 331 DD Sbjct: 391 DD 392 >4HV4-A nrPDB Length = 494 Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust. Identities = 72/324 (22%), Positives = 131/324 (40%), Gaps = 51/324 (15%) Query: 62 AGALLVSRPLDIDLPQLIV-KDTRLAFGELAAWVRQQVPARV-VALTGSSGKTSVKEMTA 119 A ++VS + D P+++ ++ R+ A + + + R +A+ G+ GKT+ M + Sbjct: 82 ASVVVVSTAISADNPEIVAAREARIPVIRRAEMLAELMRYRHGIAVAGTHGKTTTTAMLS 141 Query: 120 AILSQCG-------NTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVS 172 +I ++ G L A + +G L+ E D + + L Sbjct: 142 SIYAEAGLDPTFVNGGLVKAAGTHARLGSSRYLIAEADESDASFLHL------------- 188 Query: 173 LTRPEAALVNNLAAAHLEGF-GSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVI 231 +P A+V N+ A H++ + G + + LP G A+M D+ + Sbjct: 189 --QPMVAIVTNIEADHMDTYQGDFENLKQTFINFLHNLPFYGRAVMCIDDPVVRELLPRV 246 Query: 232 GSR-KVWRFSPNAANSDFTATNIHVTSHGTE-----FTLQTPTGS-VDVLLPLPGRHNIA 284 G + FS +A ++ + S+ E FTL+ ++V L PGRHN Sbjct: 247 GRHITTYGFSDDA--------DVQIASYRQEGPQGHFTLRRQDKPLIEVTLNAPGRHNAL 298 Query: 285 NALAAAALSMSVGATLDAIKAGLANLKAVPGRLF---------PIQLAENQLLLDDSYNA 335 NA AA A++ G + I L + GR F P+ E +L D Y Sbjct: 299 NAAAAVAVATEEGIEDEDILRALVGFQGT-GRRFDFLGNFPLAPVNGKEGSAMLVDDYGH 357 Query: 336 NVGSMTAAVQ-VLAEMPGYRVLVV 358 + + A ++ A P R++++ Sbjct: 358 HPTEVDATIKAARAGWPDKRIVML 381 >2F00-A nrPDB Length = 491 Score = 34.7 bits (78), Expect = 0.079, Method: Compositional matrix adjust. Identities = 55/226 (24%), Positives = 91/226 (40%), Gaps = 29/226 (12%) Query: 103 VALTGSSGKTSVKEMTAAILSQCG-------NTLYTAGNLNNDIGVPMTLLRLTPEYDYA 155 +A+ G+ GKT+ M ++I ++ G L A ++ +G L+ E D + Sbjct: 122 IAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAGVHARLGHGRYLIAEADESDAS 181 Query: 156 VIELGANHQGEIAWTVSLTRPEAALVNNLAAAHLEGF-GSLAGVAKAKGEIFSGLPENGI 214 + L +P A+V N+ A H++ + G + + LP G Sbjct: 182 FLHL---------------QPMVAIVTNIEADHMDTYQGDFENLKQTFINFLHNLPFYGR 226 Query: 215 AIMNADNNDWLNWQSVIGSRKV-WRFSPNAANSDFTATNIHVTSHGTEFTL-QTPTGSVD 272 A+M D+ +G + + FS +A D + FTL + + Sbjct: 227 AVMCVDDPVIRELLPRVGRQTTTYGFSEDA---DVRVEDYQQIGPQGHFTLLRQDKEPMR 283 Query: 273 VLLPLPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLF 318 V L PGRHN NA AA A++ G +AI L + + GR F Sbjct: 284 VTLNAPGRHNALNAAAAVAVATEEGIDDEAILRALESFQGT-GRRF 328 >1E8C-A nrPDB Length = 498 Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust. Identities = 76/327 (23%), Positives = 133/327 (40%), Gaps = 38/327 (11%) Query: 24 LDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAGGAGALLVS----------RPLDI 73 L +T D+R G LFVA+ G + D + QA A G A++ R + Sbjct: 21 LREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREMH- 79 Query: 74 DLPQLIVKDTRLAFGELAAWVRQQVPA---RVVALTGSSGKTSVKEMTA----------A 120 +P + + LA + P+ R+V +TG++GKT+ ++ A A Sbjct: 80 GVPVIYLSQLNERLSALAGRFYHE-PSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGEISA 138 Query: 121 ILSQCGNTLY-----TAGNLNNDIGVPMTLLRLTPE-YDYAVIELGANHQGEIAWTVSLT 174 ++ GN L T + + V L L + + +E+ ++ G + V+ Sbjct: 139 VMGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCAMEVSSH--GLVQHRVAAL 196 Query: 175 RPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNW----QSV 230 + A++ NL+ HL+ G + AK ++S G AI+NAD+ W Sbjct: 197 KFAASVFTNLSRDHLDYHGDMEHYEAAKWLLYSE-HHCGQAIINADDEVGRRWLAKLPDA 255 Query: 231 IGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAA 290 + +PN AT ++ G + G ++ L G N++N L A Sbjct: 256 VAVSMEDHINPNCHGRWLKATEVNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLLLAL 315 Query: 291 ALSMSVGATLDAIKAGLANLKAVPGRL 317 A +++G L + A L+ V GR+ Sbjct: 316 ATLLALGYPLADLLKTAARLQPVCGRM 342 >1J6U-A nrPDB Length = 469 Score = 33.9 bits (76), Expect = 0.13, Method: Compositional matrix adjust. Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 4/64 (6%) Query: 271 VDVLLPLPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPIQLAE---NQL 327 +++ L +PG HN+ NALA AL S+G L + L + V R F I + N Sbjct: 267 LELKLKVPGFHNVLNALAVIALFDSLGYDLAPVLEALEEFRGV-HRRFSIAFHDPETNIY 325 Query: 328 LLDD 331 ++DD Sbjct: 326 VIDD 329 >6FQB-A nrPDB Length = 465 Score = 33.5 bits (75), Expect = 0.17, Method: Compositional matrix adjust. Identities = 19/51 (37%), Positives = 27/51 (52%) Query: 279 GRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPIQLAENQLLL 329 G +NI NALAA A++ +GA IK G +AV GR + + + L Sbjct: 285 GLYNIYNALAAVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTL 335 >6H5E-B nrPDB Length = 437 Score = 31.6 bits (70), Expect = 0.71, Method: Compositional matrix adjust. Identities = 58/298 (19%), Positives = 110/298 (36%), Gaps = 50/298 (16%) Query: 102 VVALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIGVPMT---LLRLTPEYDYAVIE 158 +V ++G++GKT+ + L + N N ++ +T +++ TP+ AVIE Sbjct: 50 IVFISGTNGKTTTSNLIGHTL-KANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIE 108 Query: 159 LGANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIM- 217 + +G I + P + N ++ FG + + E S GI ++ Sbjct: 109 ID---EGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISN---KGIKLLL 162 Query: 218 NADN---------NDWLNWQSVIGSRKVW--------RFSPNAA---NSDFTATN----I 253 NAD+ +D + + + + R+ PN D+ N Sbjct: 163 NADDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHY 222 Query: 254 HVTSHGTEFTLQTPTGSVDVL-------------LPLPGRHNIANALAAAALSMSVGATL 300 H + S DV + + G N NALAA + +G Sbjct: 223 HCQCGFKREQAKYEISSFDVAPFLYLNINDEKYDMKIAGDFNAYNALAAYTVLRELGLNE 282 Query: 301 DAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVV 358 IK G + GR+ + + +++ + N M A++ V ++ G +V V+ Sbjct: 283 QTIKNGFETYTSDNGRMQYFKKERKEAMINLA--KNPAGMNASLSVGEQLEGEKVYVI 338 >2DY0-A nrPDB Length = 190 Score = 28.5 bits (62), Expect = 5.8, Method: Compositional matrix adjust. Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 4/71 (5%) Query: 329 LDDSYNANVGSMTAAVQVLAEMPGYRVLVVGDMAELGAESEACHVQV----GEAAKAAGI 384 + ++Y+ G+ + V A PG +VLVV D+ G EA + GE A AA I Sbjct: 103 ISETYDLEYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFI 162 Query: 385 DRVLSVGKQSH 395 + +G + Sbjct: 163 INLFDLGGEQR 173 >4TSK-A nrPDB Length = 350 Score = 28.5 bits (62), Expect = 6.4, Method: Compositional matrix adjust. Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 10/90 (11%) Query: 323 AENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGDMAELGAESEACHVQVGEAAKAA 382 A Q L D ++ +G + AE G+RV+ VG+ E ES+ + + + + A Sbjct: 31 AHAQNLRDSGFDVVIGLRPGSSWAKAEADGFRVMAVGEAVE---ESDVIMILLPDERQPA 87 Query: 383 GIDR----VLSVGKQSHAISTASGVGEHFA 408 +R L+ GK A++ A G HF+ Sbjct: 88 VYEREIRPYLTAGK---ALAFAHGFNIHFS 114 >5NEJ-1 nrPDB Length = 211 Score = 28.5 bits (62), Expect = 6.9, Method: Compositional matrix adjust. Identities = 22/54 (40%), Positives = 27/54 (50%), Gaps = 4/54 (7%) Query: 145 LLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAALVN--NLAAAHLEGFGSLA 196 LLR T Y +A +E+ H+G + W V PEAAL N N A H LA Sbjct: 65 LLR-TATYYFADLEVAVKHEGNLTW-VPNGAPEAALDNTTNPTAYHKAPLTRLA 116 >1Y3F-E nrPDB Length = 281 Score = 28.1 bits (61), Expect = 8.1, Method: Compositional matrix adjust. Identities = 20/51 (39%), Positives = 28/51 (54%), Gaps = 7/51 (13%) Query: 135 LNNDIGVPMTLLRLTPEYD-YAVIELGANHQGEIAWTVSLTRPEAALVNNL 184 LNN IGV L + P YAV LGA+ G+ +W ++ E A+ NN+ Sbjct: 75 LNNSIGV----LGVAPSASLYAVKVLGADGSGQYSWIINGI--EWAIANNM 119 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1GG4-A nrPDB 560 e-160 4QDI-A nrPDB 456 e-129 4CVK-A nrPDB 415 e-116 3ZL8-A nrPDB 407 e-114 3ZM5-A nrPDB 404 e-113 4BUB-A nrPDB 280 7e-76 4C12-A nrPDB 270 8e-73 2WTZ-A nrPDB 238 5e-63 5VVW-A nrPDB 232 2e-61 1GQY-A nrPDB 229 2e-60 6CAU-A nrPDB 225 2e-59 3LK7-A nrPDB 220 7e-58 4BUC-A nrPDB 205 5e-53 3EAG-A nrPDB 174 8e-44 Sequences not found previously or not previously below threshold: 4HV4-A nrPDB 201 4e-52 2F00-A nrPDB 189 2e-48 3HN7-A nrPDB 139 2e-33 1E8C-A nrPDB 134 1e-31 2JFH-A nrPDB 121 5e-28 6H5E-B nrPDB 97 2e-20 1J6U-A nrPDB 91 9e-19 6FQB-A nrPDB 78 1e-14 3PYZ-A nrPDB 66 3e-11 2VOR-A nrPDB 61 1e-09 1FGS-A nrPDB 52 6e-07 1O5Z-A nrPDB 52 6e-07 1W78-A nrPDB 47 2e-05 1QZX-A nrPDB 38 0.011 2IY3-A nrPDB 36 0.036 1H0O-A nrPDB 36 0.042 3SVL-A nrPDB 35 0.086 3E70-C nrPDB 34 0.17 4W8I-A nrPDB 33 0.24 3OLJ-A nrPDB 33 0.26 2UW2-A nrPDB 33 0.26 3A3J-A nrPDB 33 0.31 1XRS-B nrPDB 33 0.34 2FFH-A nrPDB 32 0.62 4ZIR-B nrPDB 31 0.84 1RJ9-B nrPDB 31 0.86 3ERR-A nrPDB 30 2.4 3W4Q-A nrPDB 30 2.6 1J8M-F nrPDB 29 5.5 5MS0-M nrPDB 29 5.7 4M60-A nrPDB 29 5.9 >1GG4-A nrPDB Length = 452 Score = 560 bits (1444), Expect = e-160, Method: Composition-based stats. Identities = 452/452 (100%), Positives = 452/452 (100%) Query: 1 MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAG 60 MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAG Sbjct: 1 MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAG 60 Query: 61 GAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA 120 GAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA Sbjct: 61 GAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA 120 Query: 121 ILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAAL 180 ILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAAL Sbjct: 121 ILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAAL 180 Query: 181 VNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFS 240 VNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFS Sbjct: 181 VNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFS 240 Query: 241 PNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATL 300 PNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATL Sbjct: 241 PNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATL 300 Query: 301 DAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGD 360 DAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGD Sbjct: 301 DAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGD 360 Query: 361 MAELGAESEACHVQVGEAAKAAGIDRVLSVGKQSHAISTASGVGEHFADKTALITRLKLL 420 MAELGAESEACHVQVGEAAKAAGIDRVLSVGKQSHAISTASGVGEHFADKTALITRLKLL Sbjct: 361 MAELGAESEACHVQVGEAAKAAGIDRVLSVGKQSHAISTASGVGEHFADKTALITRLKLL 420 Query: 421 IAEQQVITILVKGSRSAAMEEVVRALQENGTC 452 IAEQQVITILVKGSRSAAMEEVVRALQENGTC Sbjct: 421 IAEQQVITILVKGSRSAAMEEVVRALQENGTC 452 >4QDI-A nrPDB Length = 472 Score = 456 bits (1173), Expect = e-129, Method: Composition-based stats. Identities = 180/437 (41%), Positives = 247/437 (56%), Gaps = 15/437 (3%) Query: 22 ITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAGGAGALLVSRPLDIDLPQLIVK 81 + + TD+R G F+ALKGERFDAH+F Q A G +V RP+D ++ QL+V Sbjct: 41 TEIKRILTDSRHAESGDAFLALKGERFDAHNFVAQVVANGCQVAIVERPIDAEIAQLVVA 100 Query: 82 DTRLAFGELAAWVRQQ-VPARVVALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIG 140 DTRLA G+L A+ R+Q +V+ALTGSSGKT+ KEM +ILS+ TL T GNLNND+G Sbjct: 101 DTRLALGQLGAYRREQNAQLKVIALTGSSGKTTTKEMLGSILSRLAPTLITRGNLNNDLG 160 Query: 141 VPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAK 200 VPM LL L E+ YAV+ELGANHQGEI +T + +P A + N+ AHL FG G+ + Sbjct: 161 VPMMLLELRKEHQYAVMELGANHQGEIDYTSKIVQPHVAGILNIGTAHLGEFGGRDGICR 220 Query: 201 AKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGT 260 AK EI+ + G+AI+ ++ + S ++ F D AT I + Sbjct: 221 AKSEIYRHILPQGVAIVPQQDDFTAEIREAAKSHQIMSFGEGG---DVFATEIELLPQSA 277 Query: 261 EFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPI 320 F L TP GS V LP G HN+ NA AA A ++++G +L+ I GL + GRL I Sbjct: 278 NFQLHTPQGSSFVRLPFAGEHNVQNATAAVAFALALGVSLEDIVKGLEQAQGAKGRLNFI 337 Query: 321 QLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGDMAELGAESEACHVQVGEAAK 380 Q A + L +DD+YNAN SM AA QVL + G +V+V+GD+ ELG S H +G Sbjct: 338 QKAPH-LFIDDTYNANPTSMRAAAQVLLQQNGIKVMVMGDIGELGDSSWQEHHDLGRDLA 396 Query: 381 AAGIDRVLSVGKQSHAISTASGVGEHFADKTALITR---LKLLI-----AEQQVITILVK 432 +D +++VG+ A + G G H A T+ L LI + Q ++ L K Sbjct: 397 ELPLDHIVAVGQ--FASAALEGAGLHSTKLKAFQTQAEALPFLINLIQTHQPQSMSFLFK 454 Query: 433 GSRSAAMEEVVRALQEN 449 GSR ME ++ L E Sbjct: 455 GSRFTHMETLMADLMEK 471 >4CVK-A nrPDB Length = 475 Score = 415 bits (1067), Expect = e-116, Method: Composition-based stats. Identities = 207/450 (46%), Positives = 274/450 (60%), Gaps = 11/450 (2%) Query: 4 VTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAGGAG 63 + LSQLT L+ L G D AV+TD+R + PG LF+AL G RFD HD+ + A GA Sbjct: 5 LRLSQLTVALDARLIGEDAVFSAVSTDSRAIGPGELFIALSGPRFDGHDYLAEVAAKGAV 64 Query: 64 ALLVSRPL-DIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAAIL 122 A LV R + D LPQL+V+DTR A G L A R++ + A+TGSSGKT+VKEM A+IL Sbjct: 65 AALVEREVADAPLPQLLVRDTRAALGRLGALNRRKFTGPLAAMTGSSGKTTVKEMLASIL 124 Query: 123 SQ----CGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEA 178 + L T GNLNND+GVP+TLL+L P++ AVIELGA+ GEIA+TV LTRP Sbjct: 125 RTQAGDAESVLATRGNLNNDLGVPLTLLQLAPQHRSAVIELGASRIGEIAYTVELTRPHV 184 Query: 179 ALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWR 238 A++ N AH+ FG + +AKGEI GL +G A++N D+ + W++ R + Sbjct: 185 AIITNAGTAHVGEFGGPEKIVEAKGEILEGLAADGTAVLNLDDKAFDTWKARASGRPLLT 244 Query: 239 FSPNAANSDFTATNIHVTSHGTE-FTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVG 297 FS + +DF A ++ + G F LQ G V L L GRHN+ANALAAAA + ++G Sbjct: 245 FSLDRPQADFRAADLQRDARGCMGFRLQGVAGEAQVQLNLLGRHNVANALAAAAAAHALG 304 Query: 298 ATLDAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLV 357 LD I AGL L+ V GR A ++DDSYNAN SM AA+ +L+ G VLV Sbjct: 305 VPLDGIVAGLQALQPVKGRAVAQLTASGLRVIDDSYNANPASMLAAIDILSGFSGRTVLV 364 Query: 358 VGDMAELGAESEACHVQVGEAAKAAGIDRVLSVGK-QSHAISTASGVGEHFADKTALITR 416 +GDM ELG+ +E H +VG A A + + +VG +HA+ G HFAD+ +LI Sbjct: 365 LGDMGELGSWAEQAHREVG-AYAAGKVSALYAVGPLMAHAVQAFGATGRHFADQASLIGA 423 Query: 417 LKLLIAEQQVITILVKGSRSAAMEEVVRAL 446 L E TIL+KGSRSAAM++VV AL Sbjct: 424 LA---TEDPTTTILIKGSRSAAMDKVVAAL 450 >3ZL8-A nrPDB Length = 437 Score = 407 bits (1045), Expect = e-114, Method: Composition-based stats. Identities = 127/437 (29%), Positives = 207/437 (47%), Gaps = 25/437 (5%) Query: 21 DITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAGGAGALLVSRPLDIDLPQLIV 80 D+ +++++ G +FVA+KG+RFD HDF D+A GA A++ R +V Sbjct: 3 DLLTRRFVLNSKEVREGDVFVAVKGKRFDGHDFIDEALRNGAYAIIAERKTVNSDRIFLV 62 Query: 81 KDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIG 140 + + +LA VV +TGSSGKT+ KE+ +L + T GN+N + G Sbjct: 63 ESSVDTLAKLAREKLGNFSGTVVGVTGSSGKTTTKEILYNLLKNKRSVFKTPGNMNTEYG 122 Query: 141 VPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAK 200 +P+++L + V+E+ A+ G+IA + P+ A++ N+ +AHLE FG+ + + Sbjct: 123 LPLSILNDYKGEEILVLEMAASRPGDIAHLCKIAPPDVAVLLNVGSAHLEFFGTRERIME 182 Query: 201 AKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGT 260 K EI EN IA+ D+ D + V R F +S + S Sbjct: 183 TKMEIIKHSKENAIAVTLFDDPDLR--KEVPRYRNTLFFGKEGGDSVLKDWWYYEGSTIA 240 Query: 261 EFTLQTPTGSVDVLLPLPGRHN---IANALAAAALSMSVGATLDAIKAGLANLKAVPGRL 317 EF + L G N + N A+ + ++G T+D LA+LK VPGR Sbjct: 241 EFEAFDSL----FTVKLSGYWNGGQLLNIAASLCVMRTLGETVDIF--DLASLKTVPGR- 293 Query: 318 FPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGDMAELGAESEACHVQVGE 377 F ++ + L++DD+YNA+ + +++ L PG + VVG M ELG S+ H ++GE Sbjct: 294 FNVREKKGVLIVDDTYNASPEAFQTSIEALLRFPGKKFAVVGAMKELGERSKEFHEELGE 353 Query: 378 AAKA-AGIDRVLSVGK----QSHAISTASGVGEHFADKTALITRLKLLIAEQQVITILVK 432 G+ LS + +S I S E A A TR+K + +L K Sbjct: 354 RLNVLDGVYVFLSEPEAEWIKSKKIILKSDDPEKIAKDLA--TRVK------KGDVVLFK 405 Query: 433 GSRSAAMEEVVRALQEN 449 SR+ +E V+ ++ Sbjct: 406 ASRAVRIERVLEMFEKE 422 >3ZM5-A nrPDB Length = 465 Score = 404 bits (1038), Expect = e-113, Method: Composition-based stats. Identities = 131/458 (28%), Positives = 221/458 (48%), Gaps = 28/458 (6%) Query: 6 LSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAGGAGAL 65 ++Q+ N D L+ D+R + G LFV LKG R D HDF + A GA Sbjct: 8 IAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVPLKGAR-DGHDFIETAFENGAAVT 66 Query: 66 LVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAAILSQC 125 L + + + P ++V D AF LA++ ++ V A+TGS+GKT+ K+M A +LS Sbjct: 67 LSEKEVS-NHPYILVDDVLTAFQSLASYYLEKTTVDVFAVTGSNGKTTTKDMLAHLLSTR 125 Query: 126 GNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAALVNNLA 185 T T GN NN+IG+P T+L + + V+E+G +H G+I L RP+ A+V + Sbjct: 126 YKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMGQDHLGDIHLLSELARPKTAIVTLVG 185 Query: 186 AAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADN--NDWLNWQSVIGSRKVWRFSPNA 243 AHL F + +AK K +I G+ + + AD D+L +KV RF A Sbjct: 186 EAHLAFFKDRSEIAKGKMQIADGMASGSLLLAPADPIVEDYLPI-----DKKVVRFGQGA 240 Query: 244 ANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATLDAI 303 + T++ F ++D LP+ G++N NA+ A+ +++ G + + I Sbjct: 241 ---ELEITDLVERKDSLTFKANFLEQALD--LPVTGKYNATNAMIASYVALQEGVSEEQI 295 Query: 304 KAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMP----GYRVLVVG 359 + +L+ R + A +L D YNAN +M ++ + +P G ++ V+ Sbjct: 296 RLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKLILETFSAIPANEGGKKIAVLA 355 Query: 360 DMAELGAESEACHVQVGEAAKAAGIDRVLSVGKQ----SHAISTASGVGE-HFADKTALI 414 DM ELG +S H Q+ + +D V+ G+ + S +G ++ KT Sbjct: 356 DMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQLAQLASQMFPIGHVYYFKKTEDQ 415 Query: 415 TRLKLLIAEQQV-----ITILVKGSRSAAMEEVVRALQ 447 + + L+ + + IL+KGS S + ++V +L+ Sbjct: 416 DQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVESLE 453 >4BUB-A nrPDB Length = 498 Score = 280 bits (717), Expect = 7e-76, Method: Composition-based stats. Identities = 87/375 (23%), Positives = 162/375 (43%), Gaps = 25/375 (6%) Query: 2 ISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAGG 61 IS +S L D++ D+ + V+ + K+ G LF+ +GE+FD+H+ + G Sbjct: 3 ISTIVSNLKDLILEVRAPYDLEITGVSNHSSKVKKGDLFICRRGEKFDSHEIIPEVMEKG 62 Query: 62 AGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKE--MTA 119 A A++V R +D+D P + V D+R ++A+ + V+ + M Sbjct: 63 AVAVVVEREIDLDFPYIQVFDSRYFEAKVASLFFEDPWKDVLTFGVTGTNGKTTTTMMIY 122 Query: 120 AILSQCGNTL---------YTAGNLNNDIGVP-----MTLLRLTPEYDYAVIELGANHQG 165 +L+ G + +DI P ++ ++ E L + Sbjct: 123 HMLTSLGERGSVLTTAVKRILGNSYYDDITTPDAITILSAMKENREGGGKFFALEVSSHA 182 Query: 166 EIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWL 225 + V R + + N++ HL+ G+ KAK +F L ++G+A++N D Sbjct: 183 LVQQRVEGVRFDVGIFTNISRDHLDFHGTFENYLKAKLHLFDLLKDDGVAVLNESLADAF 242 Query: 226 NWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIAN 285 N + SRK+ + N+D+ NI V+ GT+F L+TP G + V G N N Sbjct: 243 NRK----SRKITF--GTSKNADYRLGNIEVSWEGTQFVLETPDGLLKVFTRAIGDFNAYN 296 Query: 286 ALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPIQLAE--NQLLLDDSYNANVGSMTAA 343 A AA A +G + + L V GR ++ A+ ++ D + + ++ Sbjct: 297 AAAAIAALHQLGYDPKDLASSLETFTGVEGRFEVVRGAKKIGLNVVVD-FAHSPDALEKL 355 Query: 344 VQVLAEMPGYRVLVV 358 ++ + ++ RV+VV Sbjct: 356 LKNVRKISQGRVIVV 370 >4C12-A nrPDB Length = 501 Score = 270 bits (690), Expect = 8e-73, Method: Composition-based stats. Identities = 107/447 (23%), Positives = 181/447 (40%), Gaps = 43/447 (9%) Query: 23 TLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAGGAGALLVSRP--LDIDLPQLIV 80 +D +TTD+R G +FVA G D+H F G ++V++ L ++ Q++V Sbjct: 22 QIDDITTDSRTAREGSIFVASVGYTVDSHKFCQNVADQGCKLVVVNKEQSLPANVTQVVV 81 Query: 81 KDTRLAFGELAAWVRQQVPAR---VVALTGSSGKTSVKEMTAAI---LSQCGNTLYTAGN 134 DT L + A P+ +TG++GKTS+ M I L + L T G Sbjct: 82 PDT-LRVASILAHTLYDYPSHQLVTFGVTGTNGKTSIATMIHLIQRKLQKNSAYLGTNGF 140 Query: 135 LNNDI------GVPMTLLRLTPEYDYAV------IELGANHQGEIAWTVSLTRPEAALVN 182 N+ P T+ LT + AV + L + G + + + A+ + Sbjct: 141 QINETKTKGANTTPETV-SLTKKIKEAVDAGAESMTLEVSSHGLVLGRLRGVEFDVAIFS 199 Query: 183 NLAAAHLEGFGSLAGVAKAKGEIFSGLPEN----GIAIMNADNNDWLNWQSVIGSRKVWR 238 NL HL+ G++ AK +FS L E+ ++N D++ + + + +V+ Sbjct: 200 NLTQDHLDFHGTMEAYGHAKSLLFSQLGEDLSKEKYVVLNNDDS-FSEYLRTVTPYEVFS 258 Query: 239 FSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGA 298 + + + F A NI + G F TP G+ V P G+ NI+N +AA S G Sbjct: 259 YGIDE-EAQFMAKNIQESLQGVSFDFVTPFGTYPVKSPYVGKFNISNIMAAMIAVWSKGT 317 Query: 299 TLDAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVV 358 +L+ I + NL+ V GRL + + L+ D Y M + + +++ + Sbjct: 318 SLETIIKAVENLEPVEGRLEVLDPSLPIDLIID-YAHTADGMNKLIDAVQPFVKQKLIFL 376 Query: 359 GDMAELGAESEACHVQVGEAAKAAGIDRVLSV--------GKQSHAISTASGVGEHF--A 408 MA G ++G A A D V+ K A +++ Sbjct: 377 VGMA--GERDLTKTPEMGRVACRA--DYVIFTPDNPANDDPKMLTAELAKGATHQNYIEF 432 Query: 409 DKTALITRLKLLIAEQQVITILVKGSR 435 D A + + IAE +L R Sbjct: 433 DDRAEGIKHAIDIAEPGDTVVLASKGR 459 >2WTZ-A nrPDB Length = 535 Score = 238 bits (606), Expect = 5e-63, Method: Composition-based stats. Identities = 107/418 (25%), Positives = 163/418 (38%), Gaps = 45/418 (10%) Query: 1 MISVTLSQLTD-----ILNGELQGA---DITLDAVTTDTRKLTPGCLFVALKGERFDAHD 52 ++ V L+ L D + G Q A D T+ VT + ++PG LF AL G Sbjct: 31 VVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALTGSTTHGAR 90 Query: 53 FADQAKAGGAGALLVSRPLDI------DLPQLIVKDTRLAFGELAAWVRQQVPAR--VVA 104 A A GA A+L +P L+ R G LAA V R V+ Sbjct: 91 HVGDAIARGAVAVLTDPAGVAEIAGRAAVPVLVHPAPRGVLGGLAATVYGHPSERLTVIG 150 Query: 105 LTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIG---VPMTLLR-------------L 148 +TG+SGKT+ + A L G G + +G +P L + Sbjct: 151 ITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPTLQAMLAAMV 210 Query: 149 TPEYDYAVIELGANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSG 208 D V+E+ + V TR NL+ HL+ S+A +AK +F Sbjct: 211 ERGVDTVVMEV--SSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEAKASLFD- 267 Query: 209 LPENGIAIMNAD--NNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVT-SHGTEFTLQ 265 P++ + A +D + S + + AT++ T + G +FT Sbjct: 268 -PDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQQFTAI 326 Query: 266 TPTG-SVDVLLPLPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPIQLAE 324 P G + + LPGR+N+AN L A A+ +VG + + GL ++ VPGRL I + Sbjct: 327 DPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIR-VPGRLEQIDRGQ 385 Query: 325 NQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGDMAELGAESEACHVQVGEAAKAA 382 L L D Y ++ + + LA P R+ VV G +G A Sbjct: 386 GFLALVD-YAHKPEALRSVLTTLAH-PDRRLAVV--FGAGGDRDPGKRAPMGRIAAQL 439 >5VVW-A nrPDB Length = 315 Score = 232 bits (592), Expect = 2e-61, Method: Composition-based stats. Identities = 78/315 (24%), Positives = 132/315 (41%), Gaps = 41/315 (13%) Query: 13 LNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAGGAGALLVSRPLD 72 L E+ G+D+ AVT K +F+ + E D GA L+VS ++ Sbjct: 31 LGYEVSGSDLKASAVTERLEKFG-AQIFIGHQAENAD-----------GADVLVVSSAIN 78 Query: 73 IDLPQLIVK-DTRLAFGELAAWVRQQVPARV-VALTGSSGKTSVKEMTAAILSQCG--NT 128 P++ + R+ A + + + R +A+ G+ GKT+ + A++ + G T Sbjct: 79 RANPEVASALERRIPVVPRAEMLAELMRYRHGIAVAGTHGKTTTTSLIASVFAAGGLDPT 138 Query: 129 LYTAGNLNN-----DIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAALVNN 183 G LN +G L+ E D + + L +P A+V N Sbjct: 139 FVIGGRLNAAGTNAQLGASRYLVAEADESDASFLHL---------------QPMVAVVTN 183 Query: 184 LAAAHLEGFG-SLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFSPN 242 + A H+ +G + K E LP G+A+M D+ I +R + Sbjct: 184 IDADHMATYGGDFNKLKKTFVEFLHNLPFYGLAVMCVDDPVVREILPQI-ARPTVTYGL- 241 Query: 243 AANSDFTATNIHVTSHGTEFTLQTPTGS-VDVLLPLPGRHNIANALAAAALSMSVGATLD 301 + ++D A NI T FT+ P +DV + +PG HN+ N+LA ++ G + + Sbjct: 242 SEDADVRAINIRQEGMRTWFTVLRPEREPLDVSVNMPGLHNVLNSLATIVIATDEGISDE 301 Query: 302 AIKAGLANLKAVPGR 316 AI GL+ + V GR Sbjct: 302 AIVQGLSGFQGV-GR 315 >1GQY-A nrPDB Length = 475 Score = 229 bits (583), Expect = 2e-60, Method: Composition-based stats. Identities = 80/374 (21%), Positives = 154/374 (41%), Gaps = 48/374 (12%) Query: 3 SVTLSQLTDIL---NGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKA 59 +S + +IL ++ G+DI VT + +++ E + Sbjct: 28 GAGMSGIAEILLNEGYQISGSDIADGVVTQRLAQAG-AKIYIGHAEEHIE---------- 76 Query: 60 GGAGALLVSRPLDIDLPQLIV-KDTRLAFGELAAWVRQQVPARV-VALTGSSGKTSVKEM 117 GA ++VS + D P+L+ K R+ + A + + + R +A+ G+ GKT+ M Sbjct: 77 -GASVVVVSSAIKDDNPELVTSKQKRIPVIQRAQMLAEIMRFRHGIAVAGTHGKTTTTAM 135 Query: 118 TAAILSQC--------GNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAW 169 + I +Q G + +AG N +G L+ E D + + L Sbjct: 136 ISMIYTQAKLDPTFVNGGLVKSAGK-NAHLGASRYLIAEADESDASFLHL---------- 184 Query: 170 TVSLTRPEAALVNNLAAAHLEGF-GSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQ 228 +P ++V N+ H++ + G + + LP G+A+M AD+ + Sbjct: 185 -----QPMVSVVTNMEPDHMDTYEGDFEKMKATYVKFLHNLPFYGLAVMCADDPVLMELV 239 Query: 229 SVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGS-VDVLLPLPGRHNIANAL 287 +G R+V + + +D+ + T +T+ P ++VLL +PG+HN NA Sbjct: 240 PKVG-RQVITYG-FSEQADYRIEDYEQTGFQGHYTVICPNNERINVLLNVPGKHNALNAT 297 Query: 288 AAAALSMSVGATLDAIKAGLANLKAVPGRLFPIQ---LAENQLLLDDSYNANVGSMTAAV 344 AA A++ G +AI LA+ + R + ++ L D Y + + + Sbjct: 298 AALAVAKEEGIANEAILEALADFQGAGRRFDQLGEFIRPNGKVRLVDDYGHHPTEVGVTI 357 Query: 345 QVLAEMPGYRVLVV 358 + E G + +V+ Sbjct: 358 KAAREGWGDKRIVM 371 >6CAU-A nrPDB Length = 472 Score = 225 bits (574), Expect = 2e-59, Method: Composition-based stats. Identities = 84/426 (19%), Positives = 158/426 (37%), Gaps = 46/426 (10%) Query: 14 NGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAGGAGALLVSRPLDI 73 ++ G+DI T + +++ + E A L+VS +D Sbjct: 36 GYKISGSDIKASKTTQQLEENGI-KVYIGHEAENI-----------KNANVLVVSTAIDP 83 Query: 74 DLPQLIVK-DTRLAFGELAAWVRQQVPARV-VALTGSSGKTSVKEMTAAIL--SQCGNTL 129 + P++ + R+ A + + + R +A+ G+ GKT+ + +L T Sbjct: 84 ENPEVKAAIEQRIPIVRRAEMLGELMRYRHGIAVAGTHGKTTTTSLLTTMLAEENLDPTY 143 Query: 130 YTAG-----NLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAALVNNL 184 G +N +G ++ E D + + L +P AA+V N+ Sbjct: 144 VIGGLLNSTGVNAALGESRFIVAEADESDASFLYL---------------QPMAAIVTNI 188 Query: 185 AAAHLEGF-GSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFSPNA 243 A H++ + GS + + LP G+A++ D+ + +G R V + N Sbjct: 189 DADHMDTYEGSFDKLKDTFVQFLHNLPFYGLAVVCGDDANIREILPRVG-RPVITYGFNE 247 Query: 244 ANSDFTATNIHVTSHGTEFT-LQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATLDA 302 N D A ++ + FT L+ + + + PG HN+ NALAA ++ G + +A Sbjct: 248 DN-DIRAIDVEQDGMRSHFTVLRKGREPLRLTINQPGLHNVLNALAAIGVATDEGVSDEA 306 Query: 303 IKAGLANLKAVPGRLFPIQ----LAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVV 358 I L V GR F +Q L E + L D Y + + A ++ + R LV+ Sbjct: 307 ISRALKGFSGV-GRRFQVQGEFELGEGNVKLVDDYGHHPKEVEATIKAARQSHPDRRLVM 365 Query: 359 GDMAELGAESEACHVQVGEAAKAAGIDRVLSVGKQSHAISTASGVGEHFADKTALITRLK 418 + + C E +L V A L +++ Sbjct: 366 LFQPHRYSRTRDCFDDFIEVLSQVDQLLLLEVYPAGEKPI-VGADSRTLARSIRLRGQVE 424 Query: 419 LLIAEQ 424 ++ + Sbjct: 425 PILIDP 430 >3LK7-A nrPDB Length = 451 Score = 220 bits (561), Expect = 7e-58, Method: Composition-based stats. Identities = 91/430 (21%), Positives = 165/430 (38%), Gaps = 57/430 (13%) Query: 34 LTPGCLFVALKGERFDAHDFADQAKAGGAGALLVSRP----------------LDIDLPQ 77 G + G+ FD + A G + S P + + P Sbjct: 29 AKLGAIVTVNDGKPFDENPTAQSLLEEGIKVVCGSHPLELLDEDFCYMIKNPGIPYNNPM 88 Query: 78 LIVK----DTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAAILSQCGNTLYTAG 133 + L ELA V + ++++ +TGS+GKT+ M A +L+ G AG Sbjct: 89 VKKALEKQIPVLTEVELAYLVSE---SQLIGITGSNGKTTTTTMIAEVLNAGGQRGLLAG 145 Query: 134 NLNNDIGVPMT-LLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAALVNNLAAAHLEGF 192 N IG P + +++ + D V+EL + V RP A++ NL HL+ Sbjct: 146 N----IGFPASEVVQAANDKDTLVMELSSFQ----LMGVKEFRPHIAVITNLMPTHLDYH 197 Query: 193 GSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATN 252 GS AK I + + + ++N + G K + A F+ T Sbjct: 198 GSFEDYVAAKWNIQNQMSSSDFLVLNFNQ----------GISKELAKTTKATIVPFSTTE 247 Query: 253 IHVTSHGTE---FTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATLDAIKAGLAN 309 ++ + F SVD + +PG HN+ NALA A++ G + I+ L+N Sbjct: 248 KVDGAYVQDKQLFYKGENIMSVDD-IGVPGSHNVENALATIAVAKLAGISNQVIRETLSN 306 Query: 310 LKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGDMAELGAESE 369 V RL + +DS + N + A + L+ +V+++ + G E + Sbjct: 307 FGGVKHRLQSLGKVHGISFYNDSKSTN---ILATQKALSGFDNTKVILIAGGLDRGNEFD 363 Query: 370 ACHVQVGEAAKAAGIDRVLSVGKQSHAIS-TASGVGEHFADKTALITRL-KLLIAEQQVI 427 + G+ ++ +G+ + + A G ++D + + K QQ Sbjct: 364 ELIPDI------TGLKHMVVLGESASRVKRAAQKAGVTYSDALDVRDAVHKAYEVAQQGD 417 Query: 428 TILVKGSRSA 437 IL+ + ++ Sbjct: 418 VILLSPANAS 427 >4BUC-A nrPDB Length = 450 Score = 205 bits (520), Expect = 5e-53, Method: Composition-based stats. Identities = 78/383 (20%), Positives = 150/383 (39%), Gaps = 42/383 (10%) Query: 62 AGALLVSRPLDIDLPQLIVKDTRLA--FGELAAWVRQQVPARVVALTGSSGKTSVKEMTA 119 + VS + D + + +R EL ++ P +VV +TG+ GK++ + Sbjct: 82 CDVVYVSPGIKPDTSMIELLSSRGVKLSTELQFFLDNVDPKKVVGITGTDGKSTATALMY 141 Query: 120 AILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAA 179 +LS G + GN G P + L EYDY V+E+ + + W+ RP + Sbjct: 142 HVLSGRGFKTFLGGNF----GTP-AVEALEGEYDYYVLEMSSFQ---LFWS---ERPYLS 190 Query: 180 --LVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVW 237 LV N++ HL+ S +K + E + + N N + + SRK+ Sbjct: 191 NFLVLNISEDHLDWHSSFKEYVDSKLKPAFLQTEGDLFVYNKHIERLRNLEG-VRSRKI- 248 Query: 238 RFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVG 297 P + +F AT + G ++TL P R NI LA + L M + Sbjct: 249 ---PFWTDENF-ATEKELIVRGKKYTLPGN-------YPYQMRENI---LAVSVLYMEMF 294 Query: 298 ATLDAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLV 357 L++ L + K +P R+ + + + +DS + ++ A+ VL+ Sbjct: 295 NELESFLELLRDFKPLPHRMEYLGQIDGRHFYNDSKATSTHAVLGALSNF----DKVVLI 350 Query: 358 VGDMAELGAESEACHVQVGEAAKAAGIDRVLSVGKQSHAISTASG-VGEHFADKTALITR 416 + + + + + E A + ++ G+ S ++ G + + Sbjct: 351 MCGIGK-----KENYSLFVEKASPK-LKHLIMFGEISKELAPFVGKIPHSIVENMEEAFE 404 Query: 417 LKLLIAEQQVITILVKGSRSAAM 439 + ++E+ + +L G S M Sbjct: 405 KAMEVSEKGDVILLSPGGASFDM 427 >4HV4-A nrPDB Length = 494 Score = 201 bits (512), Expect = 4e-52, Method: Composition-based stats. Identities = 70/364 (19%), Positives = 135/364 (37%), Gaps = 48/364 (13%) Query: 14 NGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAGGAGALLVSRPLDI 73 ++ G+D+ ++VT L F H + A ++VS + Sbjct: 46 GYQISGSDLAPNSVTQHLTALGAQIYF----------HHRPENVLD--ASVVVVSTAISA 93 Query: 74 DLPQLIV-KDTRLAFGELAAWVRQQVPARV-VALTGSSGKTSVKEMTAAILSQCG-NTLY 130 D P+++ ++ R+ A + + + R +A+ G+ GKT+ M ++I ++ G + + Sbjct: 94 DNPEIVAAREARIPVIRRAEMLAELMRYRHGIAVAGTHGKTTTTAMLSSIYAEAGLDPTF 153 Query: 131 TAGNL------NNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAALVNNL 184 G L + +G L+ E D + + L +P A+V N+ Sbjct: 154 VNGGLVKAAGTHARLGSSRYLIAEADESDASFLHL---------------QPMVAIVTNI 198 Query: 185 AAAHLEGF-GSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFSPNA 243 A H++ + G + + LP G A+M D+ +G + Sbjct: 199 EADHMDTYQGDFENLKQTFINFLHNLPFYGRAVMCIDDPVVRELLPRVGRH--ITTYGFS 256 Query: 244 ANSDFTATNIHVTSHGTEFTLQTPTGSV-DVLLPLPGRHNIANALAAAALSMSVGATLDA 302 ++D + FTL+ + +V L PGRHN NA AA A++ G + Sbjct: 257 DDADVQIASYRQEGPQGHFTLRRQDKPLIEVTLNAPGRHNALNAAAAVAVATEEGIEDED 316 Query: 303 IKAGLANLKAVPGRLFPIQL--------AENQLLLDDSYNANVGSMTAAVQVLAEMPGYR 354 I L + R + E +L D Y + + A ++ + Sbjct: 317 ILRALVGFQGTGRRFDFLGNFPLAPVNGKEGSAMLVDDYGHHPTEVDATIKAARAGWPDK 376 Query: 355 VLVV 358 +V+ Sbjct: 377 RIVM 380 >2F00-A nrPDB Length = 491 Score = 189 bits (480), Expect = 2e-48, Method: Composition-based stats. Identities = 62/304 (20%), Positives = 115/304 (37%), Gaps = 36/304 (11%) Query: 74 DLPQLIVK-DTRLAFGELAAWVRQQVPARV-VALTGSSGKTSVKEMTAAILSQCG--NTL 129 D P+++ + R+ A + + + R +A+ G+ GKT+ M ++I ++ G T Sbjct: 91 DNPEIVAAHEARIPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTF 150 Query: 130 YTAG-----NLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAALVNNL 184 G ++ +G L+ E D + + L +P A+V N+ Sbjct: 151 VNGGLVKAAGVHARLGHGRYLIAEADESDASFLHL---------------QPMVAIVTNI 195 Query: 185 AAAHLEGF-GSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFSPNA 243 A H++ + G + + LP G A+M D+ +G R+ + + Sbjct: 196 EADHMDTYQGDFENLKQTFINFLHNLPFYGRAVMCVDDPVIRELLPRVG-RQTTTYG-FS 253 Query: 244 ANSDFTATNIHVTSHGTEFTLQTPT-GSVDVLLPLPGRHNIANALAAAALSMSVGATLDA 302 ++D + FTL + V L PGRHN NA AA A++ G +A Sbjct: 254 EDADVRVEDYQQIGPQGHFTLLRQDKEPMRVTLNAPGRHNALNAAAAVAVATEEGIDDEA 313 Query: 303 IKAGLANLKAVPGRLFPIQL--------AENQLLLDDSYNANVGSMTAAVQVLAEMPGYR 354 I L + + R + +L D Y + + A ++ + Sbjct: 314 ILRALESFQGTGRRFDFLGEFPLEPVNGKSGTAMLVDDYGHHPTEVDATIKAARAGWPDK 373 Query: 355 VLVV 358 LV+ Sbjct: 374 NLVM 377 >3EAG-A nrPDB Length = 326 Score = 174 bits (440), Expect = 8e-44, Method: Composition-based stats. Identities = 70/333 (21%), Positives = 107/333 (32%), Gaps = 51/333 (15%) Query: 6 LSQLTDILNGELQGADITL-DAVTTDTRKLTPGCLFVALKGERFDAHD----FADQAKAG 60 L+ + E+ G D + ++T L ++ + D Sbjct: 20 LAAIAKEAGFEVSGCDAKMYPPMSTQLEALGI-DVYEGFDAAQLDEFKADVYVIGNVAKR 78 Query: 61 GAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA 120 G +V L++ LP + L+ V V+ + G+ GKT+ M A Sbjct: 79 GMD--VVEAILNLGLPYISGPQW------LSENVLHHHW--VLGVAGTHGKTTTASMLAW 128 Query: 121 ILSQCG-NTLYTAGNLNNDIGVPMTLLRLTPEYD------YAVIELGANHQGEIAWTVSL 173 +L G + G + + GV L + TP D + VIE Sbjct: 129 VLEYAGLAPGFLIGGVPENFGVSARLPQ-TPRQDPNSQSPFFVIEADEYDTAFFDKRSKF 187 Query: 174 T--RPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVI 231 RP A++NNL H + F L + + +P G+ + N + Sbjct: 188 VHYRPRTAVLNNLEFDHADIFADLGAIQTQFHYLVRTVPSEGLIVCNGRQQSLQDTLDK- 246 Query: 232 GSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLL----------PLPGRH 281 +T T HG + GS DVLL L GRH Sbjct: 247 --------------GCWTPVEKFGTEHGWQAGEANADGSFDVLLDGKTAGRVKWDLMGRH 292 Query: 282 NIANALAAAALSMSVGATLDAIKAGLANLKAVP 314 N NALA A + VG + L K V Sbjct: 293 NRMNALAVIAAARHVGVDIQTACEALGAFKNVK 325 >3HN7-A nrPDB Length = 524 Score = 139 bits (350), Expect = 2e-33, Method: Composition-based stats. Identities = 69/318 (21%), Positives = 115/318 (36%), Gaps = 46/318 (14%) Query: 82 DTRLAFGELAAWVRQQV--PARVVALTGSSGKTSVKEMTAAILSQCG-NTLYTAG----- 133 DT L + ++ +QV V+A+ G+ GKT+ M A IL G + + G Sbjct: 102 DTGLRYTSGPQFLSEQVLQSRHVIAVAGTHGKTTTTTMLAWILHYAGIDAGFLIGGVPLV 161 Query: 134 -----NLNNDIGVPMTLLRLTPEYD------YAVIELGANHQGEIAWTVSLT--RPEAAL 180 NL L + D Y VIE RP A+ Sbjct: 162 NTTDTNLQQVFAHSSYLGTEKDDSDNSVNTGYFVIEADEYDSAFFDKRSKFVHYRPRTAI 221 Query: 181 VNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFS 240 +NNL H + F L + + +P G IM A + + +WR S Sbjct: 222 LNNLEFDHADIFADLDAIQTQFHHMVRMIPSTGKIIMPAATISLEDTLAKGVWTPIWRTS 281 Query: 241 -------------------PNAANSDFTATNIHVTSHGTEFTLQTPTG---SVDVLLPLP 278 +SD+ A I ++ G++FT+ + V + Sbjct: 282 VIDSTISSVRREDSPLENSQAENSSDWQAELI--SADGSQFTVSFNDNKEATALVNWSMS 339 Query: 279 GRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVG 338 G HN+ NAL A A + ++G ++ A L+ + R+ I + L+ DD + + Sbjct: 340 GLHNVNNALVAIAAAYNIGVSVKTACAALSAFAGIKRRMELIGDVNDILVFDD-FAHHPT 398 Query: 339 SMTAAVQVLAEMPGYRVL 356 ++T + + R L Sbjct: 399 AITTTLDGAKKKLADRRL 416 >1E8C-A nrPDB Length = 498 Score = 134 bits (336), Expect = 1e-31, Method: Composition-based stats. Identities = 82/383 (21%), Positives = 145/383 (37%), Gaps = 33/383 (8%) Query: 8 QLTDILNGELQGA-DITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAGGAGALL 66 L D+L + A L +T D+R G LFVA+ G + D + QA A G A++ Sbjct: 4 NLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVAAII 63 Query: 67 VSRPLDID---------LPQLIVKDTRLAFGELAAWVRQQVP--ARVVALTGSSGKTSVK 115 + +P + + LA + R+V +TG++GKT+ Sbjct: 64 AEAKDEATDGEIREMHGVPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKTTTT 123 Query: 116 EMTAA---ILSQCGNTLYTAGN--------LNNDIGVPMTLLRLTP---EYDYAVIELGA 161 ++ A +L + + T GN N G + + + + Sbjct: 124 QLLAQWSQLLGEISAVMGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCAMEV 183 Query: 162 NHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADN 221 + G + V+ + A++ NL+ HL+ G + AK ++S G AI+NAD+ Sbjct: 184 SSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDMEHYEAAKWLLYSEH-HCGQAIINADD 242 Query: 222 NDWLNWQSVIGSRKVWR----FSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPL 277 W + + +PN AT ++ G + G ++ L Sbjct: 243 EVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKATEVNYHDSGATIRFSSSWGDGEIESHL 302 Query: 278 PGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANV 337 G N++N L A A +++G L + A L+ V GR+ + A + + Y Sbjct: 303 MGAFNVSNLLLALATLLALGYPLADLLKTAARLQPVCGRME-VFTAPGKPTVVVDYAHTP 361 Query: 338 GSMTAAVQVLA-EMPGYRVLVVG 359 ++ A+Q G V G Sbjct: 362 DALEKALQAARLHCAGKLWCVFG 384 >2JFH-A nrPDB Length = 445 Score = 121 bits (304), Expect = 5e-28, Method: Composition-based stats. Identities = 77/372 (20%), Positives = 138/372 (37%), Gaps = 30/372 (8%) Query: 62 AGALLVSRPLDIDLPQL-IVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA 120 A ++ S + + P L D + ++ A +VA+TGS+GK++V + Sbjct: 66 ADLIVASPGIALAHPSLSAAADAGIEIVGDIELFCREAQAPIVAITGSNGKSTVTTLVGE 125 Query: 121 ILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAAL 180 + G + GN IG+P L+ L E + V+EL + T S + AA Sbjct: 126 MAKAAGVNVGVGGN----IGLP-ALMLLDDECELYVLELSSFQ----LETTSSLQAVAAT 176 Query: 181 VNNLAAAHLEGFG-SLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRF 239 + N+ H++ + L AK I+ + ++NAD+ + + + F Sbjct: 177 ILNVTEDHMDRYPFGLQQYRAAKLRIYENAK---VCVVNADDALTMPIRGA--DERCVSF 231 Query: 240 SPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVL-LPLPGRHNIANALAAAALSMSVGA 298 N + G + ++V + L G+HN NALAA AL+ + G Sbjct: 232 GVNMGDYHLN------HQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAALALADAAGL 285 Query: 299 TLDAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVV 358 + L +P R + ++DS NVGS AA+ L + G L++ Sbjct: 286 PRASSLKALTTFTGLPHRFEVVLEHNGVRWINDSKATNVGSTEAALNGL-HVDGTLHLLL 344 Query: 359 GDMAELGAESEACHVQVGEAAKAAGIDRVLSVGKQSHAISTASGVGEHFADKTALITRLK 418 G G A + + R+ G+ ++ + RL Sbjct: 345 G-----GDGKSADFSPLARYLNGDNV-RLYCFGRDGAQLAALRPEVAEQTETMEQAMRLL 398 Query: 419 LLIAEQQVITIL 430 + + +L Sbjct: 399 APRVQPGDMVLL 410 >6H5E-B nrPDB Length = 437 Score = 96.8 bits (239), Expect = 2e-20, Method: Composition-based stats. Identities = 69/387 (17%), Positives = 131/387 (33%), Gaps = 62/387 (16%) Query: 58 KAGGAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEM 117 A A + R D+ Q+ K +LA V +V ++G++GKT+ + Sbjct: 12 LARKASRAVGKRGTDLP-GQIARKVDTDVLRKLAEQVD-----DIVFISGTNGKTTTSNL 65 Query: 118 TAAILSQCGNTLYTAGNLNNDIG---VPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLT 174 L N N ++ +++ TP+ AVIE+ G I + Sbjct: 66 IGHTLKAN-NIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDE---GSIPRVLKEV 121 Query: 175 RPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGI-AIMNADNNDWLNWQSVIGS 233 P + N ++ FG + + I + GI ++NAD+ + I S Sbjct: 122 TPSMMVFTNFFRDQMDRFGEIDIMVN---NIAETISNKGIKLLLNADDPFVSRLK--IAS 176 Query: 234 RKVWRFSPNAANSDFTAT-----------------NIHVTSHGTEFTLQTPT-------- 268 + + A +F + + + + Q Sbjct: 177 DTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYE 236 Query: 269 -GSVDVL-------------LPLPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVP 314 S DV + + G N NALAA + +G IK G + Sbjct: 237 ISSFDVAPFLYLNINDEKYDMKIAGDFNAYNALAAYTVLRELGLNEQTIKNGFETYTSDN 296 Query: 315 GRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLV--VGDMAELGAESEACH 372 GR+ + + +++ N M A++ V ++ G +V V + D A G ++ + Sbjct: 297 GRMQYFKKERKEAMIN--LAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIY 354 Query: 373 VQVGEAAKAAGIDRVLSVGKQSHAIST 399 E I+ ++ G ++ + Sbjct: 355 DADFEKLSKQQIEAIIVTGTRAEELQL 381 >1J6U-A nrPDB Length = 469 Score = 91.0 bits (224), Expect = 9e-19, Method: Composition-based stats. Identities = 69/368 (18%), Positives = 135/368 (36%), Gaps = 45/368 (12%) Query: 2 ISVTLSQLTDILNG-ELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAG 60 I ++ L + NG ++ G++I T RKL +FV + + D Sbjct: 23 IGMSAVALHEFSNGNDVYGSNIEETERTAYLRKLGI-PIFVPHSADNWYDPD-------- 73 Query: 61 GAGALLVSRPLDIDLPQLI-VKDTRLAFGELAAWVRQQVP---ARVVALTGSSGKTSVKE 116 ++ + + D P+++ + R+ + R + A+TG+ GKT+ Sbjct: 74 ---LVIKTPAVRDDNPEIVRARMERVPIENRLHYFRDTLKREKKEEFAVTGTDGKTTTTA 130 Query: 117 MTAAILS--QCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLT 174 M A +L + T++ G ++ + V EL + + ++ Sbjct: 131 MVAHVLKHLRKSPTVFLGGIMD-----SLEHGNYEKGNGPVVYELDESEEFFSEFS---- 181 Query: 175 RPEAALVNNLAAAHLEGFG-SLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGS 233 P ++ N HLE +G SL A +I + + A++ + V Sbjct: 182 -PNYLIITNARGDHLENYGNSLTRYRSAFEKISRNT---DLVVTFAEDELTSHLGDVTFG 237 Query: 234 RKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALS 293 K ++ ++ + + +++ L +PG HN+ NALA AL Sbjct: 238 VKKGTYTLEMRSAS--------RAEQKAMVEKNGKRYLELKLKVPGFHNVLNALAVIALF 289 Query: 294 MSVGATLDAIKAGLANLKAVPGRLFPI--QLAENQLLLDDSYNANVGSMTAAVQVLAE-M 350 S+G L + L + V R F I E + + D Y + +Q E Sbjct: 290 DSLGYDLAPVLEALEEFRGV-HRRFSIAFHDPETNIYVIDDYAHTPDEIRNLLQTAKEVF 348 Query: 351 PGYRVLVV 358 +++V+ Sbjct: 349 ENEKIVVI 356 >6FQB-A nrPDB Length = 465 Score = 77.6 bits (189), Expect = 1e-14, Method: Composition-based stats. Identities = 56/301 (18%), Positives = 102/301 (33%), Gaps = 60/301 (19%) Query: 100 ARVVALTGSSGKTSVKEMTAAILSQC-GNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIE 158 +V +TG++GKT +T IL + G L N G+ T L I Sbjct: 66 YEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKTGKNIA 125 Query: 159 LGANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLP--ENGIAI 216 + + ++ +P ++ N+ ++ FG + I + + Sbjct: 126 VLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFG---EIYTTYNMILDAIRKVPTATVL 182 Query: 217 MNADNNDWL-------------------------------------------NWQSVIGS 233 +N D+ + N + +G+ Sbjct: 183 LNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNTYANLGA 242 Query: 234 RKVWRFSPNAANSDFTATN-IHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAAL 292 + D+ T + +T++ + F + + + G +NI NALAA A+ Sbjct: 243 YICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIG----GLYNIYNALAAVAI 298 Query: 293 SMSVGATLDAIKAGLANLKAVPGR--LFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEM 350 + +GA IK G +AV GR F I E L+L N T A++++ Sbjct: 299 ARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLI----KNPVGATQAIEMIKLA 354 Query: 351 P 351 P Sbjct: 355 P 355 >3PYZ-A nrPDB Length = 437 Score = 66.0 bits (159), Expect = 3e-11, Method: Composition-based stats. Identities = 58/322 (18%), Positives = 108/322 (33%), Gaps = 69/322 (21%) Query: 97 QVPARVVALTGSSGKTSVKEMTAAILSQCGNTLYT------------------------- 131 + ++ + G++GK + AIL G + Sbjct: 49 KPAPKIFTVAGTNGKGTTCCTLEAILLAAGLRVGVYSSPHLLRYTERVRIQGQELSEAEH 108 Query: 132 ----------AGNLNN---DIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEA 178 G+++ + G ++ L+L + V+ L G + T ++ + Sbjct: 109 SHSFAQIEAGRGDISLTYFEFGT-LSALQLFKQAKLDVVILEVGLGGRLDAT-NIVDSDV 166 Query: 179 ALVNNLAAAHLEGFG-SLAGVAKAKGEIFSGLPEN--GIAIMNADNNDWLNWQSVIGSRK 235 A + ++A H + G + + K +F G G M D R+ Sbjct: 167 AAITSIALDHTDWLGYDRESIGREKAGVFRGGKPAVVGEPDMPQSIADVAAELGAQLYRR 226 Query: 236 --VWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNI--ANALAAAA 291 W+FS + + + + TG LP+P N+ ANA A A Sbjct: 227 DVAWKFSQQEPFDQQEPVDQQINGWHWQCGERQLTG-----LPVP---NVPLANAATALA 278 Query: 292 LSM--SVGATLDAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAE 349 + + + +AI+ GL +PGR + LL+ D N + V LA+ Sbjct: 279 VLHYSELPLSDEAIRQGLQAAS-LPGRFQVVSEQP--LLILDV-AHNPHAARYLVNRLAQ 334 Query: 350 M--------PGYRVLVVGDMAE 363 + G VVG +++ Sbjct: 335 VINPVNASKQGKVRAVVGMLSD 356 >2VOR-A nrPDB Length = 487 Score = 61.0 bits (146), Expect = 1e-09, Method: Composition-based stats. Identities = 70/368 (19%), Positives = 120/368 (32%), Gaps = 69/368 (18%) Query: 62 AGALLVSRPLDIDLPQLIVKDTRLAFGELAAWV-RQQVPARVVALTGSSGKTSVKEMTAA 120 A L V LD P+ + + L + Q + + G++GKTSV M A Sbjct: 25 ASLLQVEHLLDQRWPETRIDPSLTRISALMDLLGSPQRSYPSIHIAGTNGKTSVARMVDA 84 Query: 121 ILSQCGNTLYTAGNLNNDIGV-----------PMTLLRLTPEYDYAVIELGANHQGEIAW 169 +++ + + V P + E + V + Q Sbjct: 85 LVTALHRRTGRTTSPHLQSPVERISIDGKPISPAQYVATYREIEPLVALIDQQSQASAGK 144 Query: 170 T--------------------------------------VSLTRPEAALVNNLAAAHLEG 191 ++ A++ ++ H++ Sbjct: 145 GGPAMSKFEVLTAMAFAAFADAPVDVAVVEVGMGGRWDATNVINAPVAVITPISIDHVDY 204 Query: 192 FG-SLAGVAKAKGEIFSGLPENG---IAIMNADNNDWLNWQSVIGSRKVWRFSPNAANSD 247 G +AG+A K I + P+ +A++ + R S +S+ Sbjct: 205 LGADIAGIAGEKAGIITRAPDGSPDTVAVIGRQVPKVMEVLLAESVRA--DASVAREDSE 262 Query: 248 FTATNIHVTSHGTEFTLQTPTGSV-DVLLPLPGRHNIANALAAAALSMSVG-------AT 299 F + G LQ G D+ LPL G H NA+ A A + Sbjct: 263 FAVLRRQIAVGGQVLQLQGLGGVYSDIYLPLHGEHQAHNAVLALASVEAFFGAGAQRQLD 322 Query: 300 LDAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVG 359 DA++AG A + + PGRL ++ A + N +A Q LA +R LV G Sbjct: 323 GDAVRAGFAAVTS-PGRLERMRSAPTVFI---DAAHNPAGASALAQTLAHEFDFRFLV-G 377 Query: 360 DMAELGAE 367 ++ LG + Sbjct: 378 VLSVLGDK 385 >1FGS-A nrPDB Length = 428 Score = 51.8 bits (122), Expect = 6e-07, Method: Composition-based stats. Identities = 76/413 (18%), Positives = 132/413 (31%), Gaps = 81/413 (19%) Query: 82 DTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAAILSQCGNTLYT-----AGNLN 136 D R L A Q R + +TG++GK S A +L G T+ N Sbjct: 21 DHRRILTLLHALGNPQQQGRYIHVTGTNGKGSAANAIAHVLEASGLTVGLYTSPFIMRFN 80 Query: 137 NDI-----GVPMTLLRLT------------------------------------PEYDYA 155 I +P L + D A Sbjct: 81 ERIMIDHEPIPDAALVNAVAFVRAALERLQQQQADFNVTEFEFITALAYWYFRQRQVDVA 140 Query: 156 VIELGANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFG-SLAGVAKAKGEIFSGLPENGI 214 VIE+G G + ++ P +++ +A H + G ++ +AK K I GI Sbjct: 141 VIEVG---IGGDTDSTNVITPVVSVLTEVALDHQKLLGHTITAIAKHKAGIIKR----GI 193 Query: 215 AIMNA----DNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGS 270 ++ D + + + RF + DF+ + G FT + G Sbjct: 194 PVVTGNLVPDAAAVVAAKVATTGSQWLRF-----DRDFSVPKAKLHGWGQRFTYEDQDGR 248 Query: 271 V-DVLLPLPGRHNIANALAAAALSM------SVGATLDAIKAGLANLKAVPGRLFPIQLA 323 + D+ +PL G + N A + T I+ GLA P RL I Sbjct: 249 ISDLEVPLVGDYQQRNMAIAIQTAKVYAKQTEWPLTPQNIRQGLAA-SHWPARLEKISDT 307 Query: 324 ENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGDMAELGAESEACHVQVGEAAKAAG 383 L++ D N + + L ++ + V+ G ++ + + + AA Sbjct: 308 P--LIVIDG-AHNPDGINGLITALKQLFSQPITVIA-----GILADKDYAAMADRLTAAF 359 Query: 384 IDR-VLSVGKQSHAISTASGVGEHFADKT-ALITRLKLLIAEQQVITILVKGS 434 ++ V A+ A H + L + + I++ GS Sbjct: 360 STVYLVPVPGTPRALPEAGYEALHEGRLKDSWQEALAASLNDVPDQPIVITGS 412 >1O5Z-A nrPDB Length = 442 Score = 51.8 bits (122), Expect = 6e-07, Method: Composition-based stats. Identities = 57/313 (18%), Positives = 102/313 (32%), Gaps = 61/313 (19%) Query: 97 QVPARVVALTGSSGKTSVKEMTAAILSQCG-----------NTLYTAGNLNNDIGVPMTL 145 + + + + G++GK SV M + IL G +T LN + + Sbjct: 49 HLEYKTIHIGGTNGKGSVANMVSNILVSQGYRVGSYYSPHLSTFRERIRLNEEYISEEDV 108 Query: 146 LRLT----------------------------------PEYDYAVIELGANHQGEIAWTV 171 +++ D AV+E+G G Sbjct: 109 VKIYETMEPILNELDKEEIFSPSFFEVVTAMAFLYFAEKNVDIAVLEVG---LGGRLDAT 165 Query: 172 SLTRPEAALVNNLAAAHLEGFG-SLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSV 230 ++ P + + + H + G ++ +A K I + + L Sbjct: 166 NVVFPLCSTIVTVDRDHEKTLGYTIEQIAWEKSGIIKERVP---LVTGERKREALKVMED 222 Query: 231 IGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAA 290 + +K R + DF+ + H F D++L + G H I NA A Sbjct: 223 VARKKSSRMYV--IDKDFSVKVKSLKLHENRFDYCGENTFEDLVLTMNGPHQIENAGVAL 280 Query: 291 ALSMSVG--ATLDAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVL- 347 + G + AI+ GL N K + GR I ++ + D N + V+ L Sbjct: 281 KTLEATGLPLSEKAIREGLKNAKNL-GRFE-ILEKNGKMYILDG-AHNPHGAESLVRSLK 337 Query: 348 AEMPGYRV-LVVG 359 G + LV+G Sbjct: 338 LYFNGEPLSLVIG 350 >1W78-A nrPDB Length = 422 Score = 47.1 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 52/299 (17%), Positives = 106/299 (35%), Gaps = 59/299 (19%) Query: 102 VVALTGSSGKTSVKEMTAAILSQCGNTLYT------------------------------ 131 V + G++GK + +IL G + Sbjct: 51 VFTVAGTNGKGTTCRTLESILMAAGYKVGVYSSPHLVRYTERVRVQGQELPESAHTASFA 110 Query: 132 -----AGNLNN---DIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAALVNN 183 G+++ + G ++ L L + V+ L G + T ++ + A+V + Sbjct: 111 EIESARGDISLTYFEYGT-LSALWLFKQAQLDVVILEVGLGGRLDAT-NIVDADVAVVTS 168 Query: 184 LAAAHLEGFG-SLAGVAKAKGEIFSGLPEN--GIAIMNADNNDWLNWQSVIGSRKVWRFS 240 +A H + G + + K IF G M + D + + R+ ++ Sbjct: 169 IALDHTDWLGPDRESIGREKAGIFRSEKPAIVGEPEMPSTIADVAQEKGALLQRRGVEWN 228 Query: 241 PNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATL 300 + + D+ ++ H T ++ LPL + N A ALAA S + Sbjct: 229 YSVTDHDWAFSDAHGTLE-------------NLPLPLVPQPNAATALAALRASGLE-VSE 274 Query: 301 DAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVG 359 +AI+ G+A+ +PGR + + +++ D ++N + G + V+G Sbjct: 275 NAIRDGIASA-ILPGRFQIVSESP-RVIFDVAHNPHAAEYLTGRMKALPKNGRVLAVIG 331 >1QZX-A nrPDB Length = 440 Score = 37.5 bits (85), Expect = 0.011, Method: Composition-based stats. Identities = 42/269 (15%), Positives = 84/269 (31%), Gaps = 23/269 (8%) Query: 102 VVALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGA 161 +V + GS GKT+ A + G + LL+L + V Sbjct: 109 LVGVQGS-GKTTTAGKLAYFYKKRGYKVGLVAADVYRPAAYDQLLQLGNQIGVQVYG-EP 166 Query: 162 NHQGEIAWTVSLTRPEAA-----LVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAI 216 N+Q I ++ + A H G+G + + E++ L + + + Sbjct: 167 NNQNPIEIAKKGVDIFVKNKMDIIIVDTAGRH--GYGEETKLLEEMKEMYDVLKPDDVIL 224 Query: 217 MNADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLP 276 + RF + T + T+ G + Sbjct: 225 V------IDASIGQKAYDLASRFHQASPIGSVIITKMDGTAKGGGALSAVVATGATIKFI 278 Query: 277 LPGRH--NIANALAAAALSMSVGA-TLDAIKA---GLANLKAVPGRLFPIQLAENQLLLD 330 G + A +S +G +++I GL + ++ + + +L L Sbjct: 279 GTGEKIDELETFNAKRFVSRILGMGDIESILEKVKGLEEYDKIQKKMEDVMEGKGKLTLR 338 Query: 331 DSYNANVG--SMTAAVQVLAEMPGYRVLV 357 D Y + M +VL +PG +++ Sbjct: 339 DVYAQIIALRKMGPLSKVLQHIPGLGIML 367 >2IY3-A nrPDB Length = 432 Score = 36.0 bits (81), Expect = 0.036, Method: Composition-based stats. Identities = 56/365 (15%), Positives = 111/365 (30%), Gaps = 26/365 (7%) Query: 7 SQLTDILNGELQGADITLDAVTTDTRKLTPG--CLFVALKGERFDAHDFADQAKAGGAGA 64 ++L + + IT + + R++ V L+ R ++A Sbjct: 7 ARLQEAIGRLRGRGRITEEDLKATLREIRRALMDADVNLEVARDFVERVREEALGKQVLE 66 Query: 65 LLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAAILSQ 124 L + + +K+ L + + +V L GS GKT+ A Sbjct: 67 SLTPAEVILATVYEALKEALGGEARLPVLKDRNLWF-LVGLQGS-GKTTTAAKLALYYKG 124 Query: 125 CGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIE-LGANHQGEIAWTVS----LTRPEAA 179 G L L + V+E + I V L + Sbjct: 125 KGRRPLLVAADTQRPAAREQLRLLGEKVGVPVLEVMDGESPESIRRRVEEKARLEARDLI 184 Query: 180 LVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKV--- 236 LV+ ++ + +A+ K + P+ + +++A + KV Sbjct: 185 LVDTAGRLQIDE-PLMGELARLKEVLG---PDEVLLVLDAMTGQEALSVARAFDEKVGVT 240 Query: 237 -WRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLP-LPGRHNIANALAAAALSM 294 + ++ A G + + L P P R LA L M Sbjct: 241 GLVLTKLDGDARGGAALSARHVTGKPIYFAGVSEKPEGLEPFYPER------LAGRILGM 294 Query: 295 SVGATLDAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVG--SMTAAVQVLAEMPG 352 ++ GL + ++ + + +L L D Y + M +VL +PG Sbjct: 295 GDIESILEKVKGLEEYDKIQKKMEDVMEGKGKLTLRDVYAQIIALRKMGPLSKVLQHIPG 354 Query: 353 YRVLV 357 +++ Sbjct: 355 LGIML 359 >1H0O-A nrPDB Length = 390 Score = 35.6 bits (80), Expect = 0.042, Method: Composition-based stats. Identities = 29/162 (17%), Positives = 50/162 (30%), Gaps = 20/162 (12%) Query: 231 IGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAA 290 I +W+ A S +TA + ++ + P RH I++ LA Sbjct: 86 IEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEALKPDE----------RHFISHVLAFF 135 Query: 291 ALSMSVGATLDAIKAGL-ANLKAVPGRLFPIQLA-------ENQLLLDDSYNANVGSMTA 342 A S G + + ++ R F E LL D+Y + Sbjct: 136 AASD--GIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREY 193 Query: 343 AVQVLAEMPGYRVLVVGDMAELGAESEACHVQVGEAAKAAGI 384 + MP + + +G + +V A GI Sbjct: 194 LFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGI 235 >3SVL-A nrPDB Length = 193 Score = 34.8 bits (78), Expect = 0.086, Method: Composition-based stats. Identities = 20/112 (17%), Positives = 40/112 (35%), Gaps = 13/112 (11%) Query: 268 TGSVDVLLPLPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPIQLAENQL 327 ++ + P N ++A L + + A + L I+ A+ + Sbjct: 24 ARTLPKIAPASMEVNALPSIADIPLYDADVQQEEGFPATVEAL------AEQIRQADGVV 77 Query: 328 LLDDSYNAN-VGSMTAAVQVLAEMP-----GYRVLV-VGDMAELGAESEACH 372 ++ YN + G + A+ L+ +P G VL+ M +G H Sbjct: 78 IVTPEYNYSVPGGLKNAIDWLSRLPDQPLAGKPVLIQTSSMGVIGGARCQYH 129 >3E70-C nrPDB Length = 328 Score = 33.7 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 16/92 (17%), Positives = 29/92 (31%), Gaps = 1/92 (1%) Query: 66 LVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAAILSQC 125 ++ + + +++ R+ E + V GS GKT+ A L Sbjct: 98 IIEEAVKEAVSEILETSRRIDLIEEIRKAEKPYVIMFVGFNGS-GKTTTIAKLANWLKNH 156 Query: 126 GNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVI 157 G ++ A + G L VI Sbjct: 157 GFSVVIAASDTFRAGAIEQLEEHAKRIGVKVI 188 >4W8I-A nrPDB Length = 551 Score = 33.3 bits (74), Expect = 0.24, Method: Composition-based stats. Identities = 28/155 (18%), Positives = 54/155 (34%), Gaps = 6/155 (3%) Query: 38 CLFVALK-GERFDAHDFADQAKAGGAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQ 96 LF K G H A ++ +R ID P+++V +T A + AA + Sbjct: 150 NLFHGSKEGYGLLTHGGTTSIIEAMAAYVIRARAKGIDYPEIVVPETAHAAFKKAAELTG 209 Query: 97 QVPARVVALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAV 156 + V + +G + M++ I + +A + N I P++ L + Sbjct: 210 AILITV-PVDKKTGAVNPNVMSSYITRNTAVMVGSAPSFMNGIHDPISELGQLAKKKNVP 268 Query: 157 IE----LGANHQGEIAWTVSLTRPEAALVNNLAAA 187 LG + + V +++A Sbjct: 269 FHVDACLGGFLTAFLDTSSEPMDFRVPGVTSISAD 303 >3OLJ-A nrPDB Length = 286 Score = 33.3 bits (74), Expect = 0.26, Method: Composition-based stats. Identities = 28/162 (17%), Positives = 50/162 (30%), Gaps = 20/162 (12%) Query: 231 IGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAA 290 I +W+ A S +TA + ++ + P R+ I++ LA Sbjct: 21 IEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEE----------RYFISHVLAFF 70 Query: 291 ALSMSVGATLDAIKAGL-ANLKAVPGRLFPIQLA-------ENQLLLDDSYNANVGSMTA 342 A S G + + ++ R F E LL D+Y + Sbjct: 71 AASD--GIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREF 128 Query: 343 AVQVLAEMPGYRVLVVGDMAELGAESEACHVQVGEAAKAAGI 384 + MP + + +G + +V A GI Sbjct: 129 LFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGI 170 >2UW2-A nrPDB Length = 332 Score = 33.3 bits (74), Expect = 0.26, Method: Composition-based stats. Identities = 28/162 (17%), Positives = 50/162 (30%), Gaps = 20/162 (12%) Query: 231 IGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAA 290 I +W+ A S +TA + ++ + P R+ I++ LA Sbjct: 28 IEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEE----------RYFISHVLAFF 77 Query: 291 ALSMSVGATLDAIKAGL-ANLKAVPGRLFPIQLA-------ENQLLLDDSYNANVGSMTA 342 A S G + + ++ R F E LL D+Y + Sbjct: 78 AASD--GIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREF 135 Query: 343 AVQVLAEMPGYRVLVVGDMAELGAESEACHVQVGEAAKAAGI 384 + MP + + +G + +V A GI Sbjct: 136 LFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGI 177 >3A3J-A nrPDB Length = 344 Score = 32.9 bits (73), Expect = 0.31, Method: Composition-based stats. Identities = 44/307 (14%), Positives = 96/307 (31%), Gaps = 35/307 (11%) Query: 79 IVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNND 138 + D R L + + VV + GK +M S G + + D Sbjct: 26 LNPDQRQYPASLTKM----MTSYVVGVALKQGKIHNTDMVTIGESAWGRNFPDSSKMFLD 81 Query: 139 IGVPMTLLRLTPE-----YDYAVIELGANHQGEIAWTVSLTRPEAALV----NNLAAAH- 188 + +++ L + A + L + G + V N H Sbjct: 82 LNTQVSVADLNRGVIVVSGNDATVALAEHISGNVPNFVETMNKYVQQFGLKNTNFTTPHG 141 Query: 189 LEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFSP-NAANSD 247 L+ + A+ +AI+ A L + I S K + F+ N + Sbjct: 142 LD---DPNQYSSAR----------DMAIIGAHIIRDLPEEYKIYSEKDFTFNKIKQPNRN 188 Query: 248 FTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATLDA---IK 304 + + G + T T +++ +N+ + G +++ ++ Sbjct: 189 GLLWDKTINVDGMK-TGHTSQAGYNLVASATTSNNMRLISVVMGVPTYKGREVESKKLLQ 247 Query: 305 AGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGDMAEL 364 G AN + +++E ++ D + +G+ + +P + V EL Sbjct: 248 WGFANFETFKTLEAGKEISEQRVYYGDKNSVKLGAF---MDHFITIPKGKQSEVKARYEL 304 Query: 365 GAESEAC 371 ++ Sbjct: 305 ADKNLQA 311 >1XRS-B nrPDB Length = 262 Score = 32.9 bits (73), Expect = 0.34, Method: Composition-based stats. Identities = 39/213 (18%), Positives = 76/213 (35%), Gaps = 36/213 (16%) Query: 255 VTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATLDAIK--AGLAN--- 309 + G V + LP ++N +A AA +++ +G ++ L Sbjct: 18 DLERVKPYGDTMNDGKVQLSFTLPLKNNERSAEAAKQIALKMGLEEPSVVMQQSLDEEFT 77 Query: 310 LKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGDMAELGAESE 369 V G +Q + ++ N+ + SM + + E G +++VVG Sbjct: 78 FFVVYG--NFVQSVNYNEIHVEAVNSEILSMEETDEYIKENIGRKIVVVGA--------- 126 Query: 370 ACHVQVGEAAKAAGIDRVLS-------VGKQSHAISTASGVG-----EHFADKTALITRL 417 G A GID +++ G + + + A +G E F K + Sbjct: 127 ----STGTDAHTVGIDAIMNMKGYAGHYGLERYEMIDAYNLGSQVANEDFIKKAVELEAD 182 Query: 418 KLLIAEQQVITILVKGSRSAAMEEVVRALQENG 450 LL+++ T+ K M ++ L+ G Sbjct: 183 VLLVSQ----TVTQKNVHIQNMTHLIELLEAEG 211 >2FFH-A nrPDB Length = 425 Score = 31.7 bits (70), Expect = 0.62, Method: Composition-based stats. Identities = 26/169 (15%), Positives = 48/169 (28%), Gaps = 5/169 (2%) Query: 7 SQLTDILNGELQGADITLDAVTTDTRKLTPG--CLFVALKGERFDAHDFADQAKAGGAGA 64 ++L + + IT + + R++ V L+ R ++A Sbjct: 7 ARLQEAIGRLRGRGRITEEDLKATLREIRRALMDADVNLEVTRDFVERVREEALGKQVLE 66 Query: 65 LLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAAILSQ 124 L + + +K+ L + + +V L GS GKT+ A Sbjct: 67 SLTPAEVILATVYEALKEALGGEARLPVLKDRNLWF-LVGLQGS-GKTTTAAKLALYYKG 124 Query: 125 CGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIE-LGANHQGEIAWTVS 172 G L L + V+E + I V Sbjct: 125 KGRRPLLVAADTQRPAAREQLRLLGEKVGVPVLEVMDGESPESIRRRVE 173 >4ZIR-B nrPDB Length = 268 Score = 31.3 bits (69), Expect = 0.84, Method: Composition-based stats. Identities = 36/182 (19%), Positives = 62/182 (34%), Gaps = 16/182 (8%) Query: 102 VVALTGSSGKTSVKEMTAAILSQCG---------NTLYTAGNLNNDIGVPMT-LLRLTPE 151 VV GS GKT++ ++ A +L+ G + N+ P + ++ T E Sbjct: 42 VVGKNGS-GKTTLLKILAGLLAAAGEIFLDGSPADPFLLRKNVGYVFQNPSSQIIGATVE 100 Query: 152 YDYAV-IELGANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLP 210 D A +E+ + E+ + L AA L G K + I S L Sbjct: 101 EDVAFSLEIMGLDESEMRKRIKKVLELVGLSGLAAADPLNLSGG----QKQRLAIASMLA 156 Query: 211 ENGIAIMNADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGS 270 + + + L+ S +V N T+ +F L G+ Sbjct: 157 RDTRFLALDEPVSMLDPPSQREIFQVLESLKNEGKGIILVTHELEYLDDMDFILHISNGT 216 Query: 271 VD 272 +D Sbjct: 217 ID 218 >1RJ9-B nrPDB Length = 300 Score = 31.3 bits (69), Expect = 0.86, Method: Composition-based stats. Identities = 26/169 (15%), Positives = 48/169 (28%), Gaps = 5/169 (2%) Query: 7 SQLTDILNGELQGADITLDAVTTDTRKLTPG--CLFVALKGERFDAHDFADQAKAGGAGA 64 ++L + + IT + + R++ V L+ R ++A Sbjct: 7 ARLQEAIGRLRGRGRITEEDLKATLREIRRALMDADVNLEVTRDFVERVREEALGKQVLE 66 Query: 65 LLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAAILSQ 124 L + + +K+ L + + +V L GS GKT+ A Sbjct: 67 SLTPAEVILATVYEALKEALGGEARLPVLKDRNLWF-LVGLQGS-GKTTTAAKLALYYKG 124 Query: 125 CGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIE-LGANHQGEIAWTVS 172 G L L + V+E + I V Sbjct: 125 KGRRPLLVAADTQRPAAREQLRLLGEKVGVPVLEVMDGESPESIRRRVE 173 >3ERR-A nrPDB Length = 536 Score = 29.8 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 29/75 (38%), Gaps = 2/75 (2%) Query: 358 VGDMAELGAESEACHVQVGEAAKAAGIDRVLSVGKQSHAISTASGVGEHFADKTALITRL 417 + D+ L E E H + E A ++ +L+V +Q H + + ++ Sbjct: 1 MVDLKRLRQEPEVFHRAIREKGVALDLEALLAVDEQLHKQQEVIADKQMSVK--EDLDKV 58 Query: 418 KLLIAEQQVITILVK 432 + + E Q +K Sbjct: 59 EPAVIEAQNAVKSIK 73 >3W4Q-A nrPDB Length = 258 Score = 29.8 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 12/81 (14%), Positives = 26/81 (32%) Query: 153 DYAVIELGANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPEN 212 AV+ H G + V+ R + + + H++ ++A + A + N Sbjct: 46 GAAVLAQSVAHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAAN 105 Query: 213 GIAIMNADNNDWLNWQSVIGS 233 + + IG Sbjct: 106 ELMKRIGGPAAVTAYARSIGD 126 >1J8M-F nrPDB Length = 297 Score = 28.6 bits (62), Expect = 5.5, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 14/32 (43%), Gaps = 1/32 (3%) Query: 102 VVALTGSSGKTSVKEMTAAILSQCGNTLYTAG 133 +V + G+ GKT+ A + G + G Sbjct: 103 LVGVQGT-GKTTTAGKLAYFYKKKGFKVGLVG 133 >5MS0-M nrPDB Length = 497 Score = 28.6 bits (62), Expect = 5.7, Method: Composition-based stats. Identities = 23/135 (17%), Positives = 38/135 (28%), Gaps = 7/135 (5%) Query: 203 GEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEF 262 + S L + +M D+ + + + + + DF + E Sbjct: 327 VRLASQLSGWELNVMTVDDLQAKHQAEAHAAIDTFTKYLD-IDEDFATVLVEEGFSTLEE 385 Query: 263 TLQTP------TGSVDVLLPLPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGR 316 P +D R NALA A + + L NL+ V Sbjct: 386 LAYVPMKELLEIEGLDEPTVEALRERAKNALATIAQAQQESLGDNKPADDLLNLEGVDRD 445 Query: 317 LFPIQLAENQLLLDD 331 L A L+D Sbjct: 446 LAFKLAARGVCTLED 460 >4M60-A nrPDB Length = 418 Score = 28.6 bits (62), Expect = 5.9, Method: Composition-based stats. Identities = 33/224 (14%), Positives = 58/224 (25%), Gaps = 39/224 (17%) Query: 182 NNLAAAHLEGFG-SLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFS 240 AH+ F + G E+ L G + A + + + G+R V S Sbjct: 6 TQTTPAHIAMFSIAAHGHVNPSLEVIRELVARGHRVTYAIPPVFADKVAATGARPVLYHS 65 Query: 241 P-NAANSDFTAT------NIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALS 293 ++D A N+ + L + +P H+I + A L+ Sbjct: 66 TLPGPDADPEAWGSTLLDNVEPFLNDAIQALPQLADAYADDIPDLVLHDIT-SYPARVLA 124 Query: 294 MSVGATLDAIKAGLANLKAVP---------------------GRLFPIQLAENQLLLDDS 332 G ++ L K R D+ Sbjct: 125 RRWGVPAVSLSPNLVAWKGYEEEVAEPMWREPRQTERGRAYYARFEAWLKENGITEHPDT 184 Query: 333 YNANVGSMTAAVQVLAEMPGYRV---------LVVGDMAELGAE 367 + ++ + + RV GD AE G Sbjct: 185 FASHPPRSLVLIPKALQPHADRVDEDVYTFVGACQGDRAEEGGW 228 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.120 0.275 Lambda K H 0.267 0.0372 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,842,559 Number of Sequences: 36641 Number of extensions: 444253 Number of successful extensions: 1680 Number of sequences better than 10.0: 53 Number of HSP's better than 10.0 without gapping: 51 Number of HSP's successfully gapped in prelim test: 38 Number of HSP's that attempted gapping in prelim test: 1517 Number of HSP's gapped (non-prelim): 104 length of query: 452 length of database: 10,336,785 effective HSP length: 100 effective length of query: 352 effective length of database: 6,672,685 effective search space: 2348785120 effective search space used: 2348785120 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.9 bits)