BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P11859 (477 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2WXX-A nrPDB 916 0.0 2WXZ-C nrPDB 803 0.0 5M3Y-A nrPDB 540 e-154 6EE5-A nrPDB 103 2e-22 5INW-A nrPDB 96 3e-20 5HGC-A nrPDB 81 1e-15 2OL2-A nrPDB 80 3e-15 4AJT-A nrPDB 77 1e-14 2VDY-A nrPDB 76 3e-14 3DY0-A nrPDB 74 2e-13 4Y40-A nrPDB 72 8e-13 3NE4-A nrPDB 70 2e-12 3ZHA-A nrPDB 70 3e-12 1JMJ-A nrPDB 69 3e-12 2V95-A nrPDB 68 9e-12 6HGE-B nrPDB 67 2e-11 4ZK0-A nrPDB 66 3e-11 4AJU-A nrPDB 62 7e-10 1C8O-A nrPDB 61 1e-09 1IMV-A nrPDB 60 2e-09 1M93-B nrPDB 60 2e-09 4KDS-A nrPDB 60 3e-09 1UHG-A nrPDB 58 1e-08 1YXA-A nrPDB 57 1e-08 4EB1-I nrPDB 53 3e-07 1QMB-A nrPDB 53 4e-07 1BY7-A nrPDB 52 5e-07 4DTE-A nrPDB 52 5e-07 1ATT-A nrPDB 52 7e-07 2R9Y-A nrPDB 51 1e-06 2OAY-A nrPDB 48 1e-05 3F02-A nrPDB 46 3e-05 2XN5-A nrPDB 45 6e-05 1JJO-C nrPDB 45 9e-05 3NDA-A nrPDB 44 1e-04 6F4U-A nrPDB 43 2e-04 6F02-A nrPDB 43 3e-04 6CJ7-A nrPDB 43 3e-04 4DY0-A nrPDB 42 7e-04 4P0F-A nrPDB 40 0.002 4GA7-A nrPDB 40 0.003 5NCS-A nrPDB 39 0.006 1C5G-A nrPDB 38 0.012 1HLE-A nrPDB 36 0.042 1SNG-A nrPDB 32 0.48 3LW2-A nrPDB 32 0.87 2PEF-A nrPDB 31 0.99 3LE2-A nrPDB 30 1.7 1MTP-A nrPDB 30 2.0 3ICO-A nrPDB 30 2.2 3PZF-A nrPDB 30 2.5 1V9D-A nrPDB 28 8.2 3OBV-E nrPDB 28 9.2 >2WXX-A nrPDB Length = 453 Score = 916 bits (2367), Expect = 0.0, Method: Compositional matrix adjust. Identities = 448/453 (98%), Positives = 451/453 (99%) Query: 25 DRVYIHPFHLLYHNKSTCAQLENPSVETLPESTFEPVPIQAKTSPVNEKTLHDQLVLAAE 84 DRVYIHPFHLLYHNKSTCAQLENPSVETLPESTFEPVPIQAKTSPVNEKTLHDQLVLAAE Sbjct: 1 DRVYIHPFHLLYHNKSTCAQLENPSVETLPESTFEPVPIQAKTSPVNEKTLHDQLVLAAE 60 Query: 85 KLEDEDRKRAAQVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPT 144 KLEDEDRKRAAQVAMI NFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPT Sbjct: 61 KLEDEDRKRAAQVAMITNFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPT 120 Query: 145 ASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTA 204 ASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSI+VGLFTA Sbjct: 121 ASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIVVGLFTA 180 Query: 205 PGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTD 264 PGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTD Sbjct: 181 PGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTD 240 Query: 265 STLLFNTYVHFQGTMRGFSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTC 324 STLLFNTYVHFQGTMRGFSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTC Sbjct: 241 STLLFNTYVHFQGTMRGFSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTC 300 Query: 325 VPLGERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQ 384 VPLGERATLLLIQPHC SDLDRVEALIF+NDLLTWIENPPPRAIRLTLPQLEIRGSYNLQ Sbjct: 301 VPLGERATLLLIQPHCISDLDRVEALIFQNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQ 360 Query: 385 DLLAEDKLPTLLGAEANLSNIGDTNPRVGEVLNSILLELKAGEEEQPTTSVQQPGSPEAL 444 DLLAEDKLPTLLGAEANL+NIGDTNPRVGEVLNSILLELKAGEEEQPTTSVQQPGSPEAL Sbjct: 361 DLLAEDKLPTLLGAEANLNNIGDTNPRVGEVLNSILLELKAGEEEQPTTSVQQPGSPEAL 420 Query: 445 DVTLSSPFLFAIYEQDSGTLHFLGRVNNPQSVV 477 DVTLSSPFLFAIYEQDSGTLHFLGRVNNPQSVV Sbjct: 421 DVTLSSPFLFAIYEQDSGTLHFLGRVNNPQSVV 453 >2WXZ-C nrPDB Length = 453 Score = 803 bits (2074), Expect = 0.0, Method: Compositional matrix adjust. Identities = 390/453 (86%), Positives = 417/453 (92%) Query: 25 DRVYIHPFHLLYHNKSTCAQLENPSVETLPESTFEPVPIQAKTSPVNEKTLHDQLVLAAE 84 DRVYIHPFHLLY++KSTCAQLENPSVETLPE TFEPVPIQAKTSPV+EKTL D+LVLA E Sbjct: 1 DRVYIHPFHLLYYSKSTCAQLENPSVETLPEPTFEPVPIQAKTSPVDEKTLRDKLVLATE 60 Query: 85 KLEDEDRKRAAQVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPT 144 KLE EDR+RAAQVAMIANF+GFRMYKML+EA ASGA+LSPPALFGTLVSFYLGSLDPT Sbjct: 61 KLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPT 120 Query: 145 ASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTA 204 ASQLQ LL VPVKEGDCTSRLDGHKVL AL+AVQGLLVTQGGSSSQTPLLQS +VGLFTA Sbjct: 121 ASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTA 180 Query: 205 PGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTD 264 PG RLK FV+SL FTPA+FPRSLDLSTDPVLA +KINRF++AVTGWKMNLPLEGVSTD Sbjct: 181 PGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTD 240 Query: 265 STLLFNTYVHFQGTMRGFSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTC 324 STL FNTYVHFQG MRGFSQL G+HEFWVDNS SVSVPM+SGTGNFQHWSDAQNNFSVT Sbjct: 241 STLFFNTYVHFQGKMRGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTR 300 Query: 325 VPLGERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQ 384 VPLGE TLLLIQP C SDLDRVE L+F++D LTWI+NPPPRAIRLTLPQLEIRGSYNLQ Sbjct: 301 VPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQ 360 Query: 385 DLLAEDKLPTLLGAEANLSNIGDTNPRVGEVLNSILLELKAGEEEQPTTSVQQPGSPEAL 444 DLLA+ KL TLLGAEANL +GDTNPRVGEVLNSILLEL+AGEEEQPT S QQPGSPE L Sbjct: 361 DLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQPGSPEVL 420 Query: 445 DVTLSSPFLFAIYEQDSGTLHFLGRVNNPQSVV 477 DVTLSSPFLFAIYE+DSG LHFLGRV+NPQ+VV Sbjct: 421 DVTLSSPFLFAIYERDSGALHFLGRVDNPQNVV 453 >5M3Y-A nrPDB Length = 458 Score = 540 bits (1390), Expect = e-154, Method: Compositional matrix adjust. Identities = 274/452 (60%), Positives = 327/452 (72%), Gaps = 3/452 (0%) Query: 25 DRVYIHPFHLLYHNKSTCAQLENPSVETLPESTFEPVPIQAKTSPVNEKTLHDQLVLAAE 84 DRVYIHPFHL+ HN+STC QL + + TF P PIQAKTSPV+EK L DQLVL A Sbjct: 1 DRVYIHPFHLVIHNESTCEQLAKANAGKPKDPTFIPAPIQAKTSPVDEKALQDQLVLVAA 60 Query: 85 KLEDEDRKRAAQVAMIANFVGFRMYKMLNEAGSGASGA-ILSPPALFGTLVSFYLGSLDP 143 KL+ ED+ RAA V M+ANF+GFR+Y M +E GA +LSP A+FGTL S YLG+LD Sbjct: 61 KLDTEDKLRAAMVGMLANFLGFRIYGMHSELWGVVHGATVLSPTAVFGTLASLYLGALDH 120 Query: 144 TASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFT 203 TA +LQ +L VP K+ CTSRLD HKVL+AL+AVQGLLV QG + SQ LL S +VG+FT Sbjct: 121 TADRLQAILGVPWKDKQCTSRLDAHKVLSALQAVQGLLVAQGRADSQAQLLLSTVVGVFT 180 Query: 204 APGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVST 263 APG LK FVQ LAL+TP + PRSLD T+ +A EKI+RF++AVTGWK L G S Sbjct: 181 APGLHLKQPFVQGLALYTPVVLPRSLDF-TELDVAAEKIDRFMQAVTGWKTGSSLMGASV 239 Query: 264 DSTLLFNTYVHFQGTMRGFSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVT 323 DSTL FNTYVHFQG M+GFS L EFWVD S SVSVPM+SG G FQHWSD Q+ FSVT Sbjct: 240 DSTLAFNTYVHFQGKMKGFSLLAEPQEFWVDQSTSVSVPMLSGMGTFQHWSDIQDQFSVT 299 Query: 324 CVPLGERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNL 383 VP E A+LLLIQPH SDLD+VE L F+ + L W++ PR I LT+PQL ++GSY+L Sbjct: 300 QVPFTESASLLLIQPHYASDLDKVEGLTFQQNSLNWMKKLSPRTIHLTMPQLVLQGSYDL 359 Query: 384 QDLLAEDKLPTLLGAEANLSNIGDTNPRVGEVLNSILLELKAGEEEQPTTSVQQPGSPEA 443 QDLLA+ +LP +L E NL + + RVGEVLNSI EL+A E E PT S QQ PE Sbjct: 360 QDLLAQAELPAILHTELNLQKLSNDRIRVGEVLNSIFFELEADERE-PTESTQQLNKPEV 418 Query: 444 LDVTLSSPFLFAIYEQDSGTLHFLGRVNNPQS 475 L+VTL+ PFLFA+Y+Q + LHFLGRV NP S Sbjct: 419 LEVTLNRPFLFAVYDQSATALHFLGRVANPLS 450 >6EE5-A nrPDB Length = 379 Score = 103 bits (256), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 77/278 (27%), Positives = 139/278 (50%), Gaps = 9/278 (3%) Query: 200 GLFTAPGFRLKHSFVQ-SLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPL 258 GLF +L SF++ S L+ F S+D DP A ++IN +++ T K+ L Sbjct: 107 GLFVDKSLKLLDSFLEDSKKLYQAEAF--SVDF--DPEEAKKQINDWVEKQTNGKIKDLL 162 Query: 259 EGVSTDSTLLFNTYVHFQGTMRGFSQLPGVHE--FWVDNSISVSVPMISGTGNFQHWSDA 316 + + +D+ L+ ++F+G + E F VD +V VPM+S G F ++ D Sbjct: 163 KDLDSDTVLVLVNAIYFKGKWKKPFDPENTKEEDFHVDEKTTVKVPMMSQKGKFYYYHDD 222 Query: 317 QNNFSVTCVPLGERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLE 376 + + V +P A++L+I P L +E + L W+++ R++ L LP+ + Sbjct: 223 ELSCKVLELPYKGNASMLIILPD-EGGLQHLEQSLTPETLSKWLKSLTRRSVELYLPKFK 281 Query: 377 IRGSYNLQDLLAEDKLPTLLGAEANLSNIGDTNPRVGEVLNSILLEL-KAGEEEQPTTSV 435 I G+Y+L+++L+ + L A+LS I + V + ++ +LE+ + G E T + Sbjct: 282 IEGTYDLKEVLSNLGITDLFSPGADLSGITEEKLYVSKAVHKAVLEVNEEGTEAAAATFL 341 Query: 436 QQPGSPEALDVTLSSPFLFAIYEQDSGTLHFLGRVNNP 473 + + PFLF I E +G++ F+G+V NP Sbjct: 342 EAIPMSIPPEFKADRPFLFLIRENKTGSILFMGKVVNP 379 >5INW-A nrPDB Length = 421 Score = 95.9 bits (237), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 102/398 (25%), Positives = 172/398 (43%), Gaps = 32/398 (8%) Query: 24 GDRVYIHPFHLLYHNKSTCAQLENPSVETLPESTFEPVPIQAKTSPVNEKTLHDQLVLAA 83 G+R Y+ PFHL+ + S A E P E+ P P+ SP Sbjct: 1 GERPYMQPFHLIPPSLSVQAT-EQPLASN--EAWDYPEPLAPGQSPAASSEEGSSEEKGD 57 Query: 84 EKLEDEDRKRAA----------QVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTL 133 E+ D + ++A N +GFR+YK + A SP ++ L Sbjct: 58 EREPHGDEGKRGRKDKKKSKTQRIASAVNGLGFRLYKQVLGGAGPADNIFFSPLSIASAL 117 Query: 134 VSFYLGSLDPTASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPL 193 G+ T ++L T L L G K +++ L S+ L Sbjct: 118 GVVTAGANGSTRAELDTALG-------FKEFLHGKKKAKSMKYFARLNGALYKRSAGFEL 170 Query: 194 LQSIMVGLFTAPGFRLKHSFVQSLA-LFTPALFPRSLDLSTDPVLATEKINRFIKAVTGW 252 + +V F+ G L F +++A LF + RS+D D A E +N +I+ VT Sbjct: 171 MGKNVV--FSKKGLWLYRQFTRTVAHLFKSNV--RSVDFG-DSKNAVELMNAYIEKVTSK 225 Query: 253 KMNLPLEGVSTDSTLLFNTYVHFQGTMRGFSQLPGVHE---FWVDNSISVSVPMISGTGN 309 K + V TD++L+ ++F+G+ G P + + FWV++S S+ VP + Sbjct: 226 KFPDVISDVDTDTSLVIVNVIYFKGSW-GNKFEPDLTKNVRFWVNSSYSMMVPTMHQRAK 284 Query: 310 FQHWSDAQNNFSVTCVPLGERATLLLIQPHCTSDLDRVEALIFRNDLLTWIE--NPPPRA 367 + D + +V +P A++L+I PH T DL +VE + + L W+ P Sbjct: 285 LSYTQDRKLRSTVVKLPYEGGASMLVIVPHRTEDLPKVEESVSQEQLEEWLSLLGPSNHY 344 Query: 368 IRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNI 405 ++L+LP+ +I SY+L+ L+ + ++ A+LS I Sbjct: 345 VQLSLPKFKISVSYDLKAYLSAMGMSSMFSYGADLSRI 382 >5HGC-A nrPDB Length = 380 Score = 80.9 bits (198), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 66/283 (23%), Positives = 135/283 (47%), Gaps = 9/283 (3%) Query: 196 SIMVGLFTAPGFRLKHSFVQ-SLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKM 254 ++M +F L F+ + AL+ F + P A ++IN +I+ T K+ Sbjct: 98 NMMNAIFVTAALALLRKFLDDAKALYQLEAFTTDFN---KPTEAEKQINDYIERKTHGKI 154 Query: 255 NLPLEGVSTDSTLLFNTYVHFQGTMRG--FSQLPGVHEFWVDNSISVSVPMISGTGNFQH 312 ++ + + +L ++V+F+G+ ++ EF+VD +V VPM+ G F Sbjct: 155 TNLVKDMDPQTVMLLASFVYFKGSWEKPFEAEHTEEREFFVDAETTVKVPMMYQMGRFDF 214 Query: 313 WSDAQNNFSVTCVPLGERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTL 372 + D + + +V + AT L+ P + ++E + + + W ++ R + L Sbjct: 215 YFDEELSCTVVRLHYNGSATAFLVLP-AKGKMKQLEQTLDKETIQKWSDHLFQRFMNLYF 273 Query: 373 PQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNI-GDTNPRVGEVLNSILLEL-KAGEEEQ 430 P+ I GSY + + L + + + +A+LS I G + +V +V++ L++ + G E Sbjct: 274 PKFSISGSYEISNTLRKMGIVDVFTNQADLSGITGSPDLKVSKVVHKASLDVDEKGTEAA 333 Query: 431 PTTSVQQPGSPEALDVTLSSPFLFAIYEQDSGTLHFLGRVNNP 473 T+V+ + S PFL I+++D+ + F+G++ NP Sbjct: 334 AATAVEIMPISFPPTIEFSHPFLMLIFDRDTNSTLFIGKIVNP 376 >2OL2-A nrPDB Length = 395 Score = 79.7 bits (195), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 71/286 (24%), Positives = 129/286 (45%), Gaps = 23/286 (8%) Query: 200 GLFTAPGFRLKHSFVQSLA-LFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPL 258 LFT L+ +FV ++ L+ FP + D A ++IN ++ T K+ L Sbjct: 121 ALFTDLVVDLQDTFVSAMKTLYLADTFPTNF---RDSAGAMKQINDYVAKQTKGKIVDLL 177 Query: 259 EGVSTDSTLLFNTYVHFQGTMRGFSQLPGVHE--FWVDNSISVSVPMISGTGNFQHWSDA 316 + + +++ ++ Y+ F+ G E F+V + V VPM+S + + D Sbjct: 178 KNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSREDQYHYLLDR 237 Query: 317 QNNFSVTCVPLGERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLE 376 + V VP AT L I P + +VE + L W++ R + L LP+ Sbjct: 238 NLSCRVVGVPYQGNATALFILP-SEGKMQQVENGLSEKTLRKWLKMFKKRQLELYLPKFS 296 Query: 377 IRGSYNLQDLLAEDKLPTLLGAEANLSNIGD-TNPRVGEVLNSILLELKAGEEEQPTTSV 435 I GSY L+ +L + + + A+LS I + +N +V E+++ ++E+ +E T + Sbjct: 297 IEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEV----DESGTRAA 352 Query: 436 QQPGSP--------EALDVTLSSPFLFAIYEQDSGTLHFLGRVNNP 473 G+ + + + PFL I + + + FLG+VN P Sbjct: 353 AATGTIFTFRSARLNSQRLVFNRPFLMFIVDNN---ILFLGKVNRP 395 >4AJT-A nrPDB Length = 427 Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 64/242 (26%), Positives = 111/242 (45%), Gaps = 15/242 (6%) Query: 242 INRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMR-----GFSQLPGVHEFWVDNS 296 IN I T K+ + ++ ++ L+ YV F+G F++ H +D Sbjct: 188 INHCIVKETEGKIPKLFDEINPETKLILVDYVLFKGKWLTPFDPSFTEADTFH---LDKY 244 Query: 297 ISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATLLLIQPHCTSDLDRVEALIFRNDL 356 ++ VPM+ GNF D + + +P AT+L++ T D +E + + + Sbjct: 245 RAIKVPMMYREGNFTSTFDKKFRCHILKLPYQGNATMLVVLMEKTGDYLALEDYLTVDLV 304 Query: 357 LTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNIGDT--NPRVGE 414 TW++N R + + P+ ++ Y + +LL + + L A+LS + N +V Sbjct: 305 ETWLQNMKTRKMEVFFPKFKLNQRYEMHELLKQMGIRRLFSTSADLSELSAMARNLQVSR 364 Query: 415 VLNSILLELKAGEEEQPTTSVQQ---PGSPEALDVTLSSPFLFAIYEQDSGTLHFLGRVN 471 VL +LE+ E + ++ + P A+ V + PF F IYE+ S L FLGRV Sbjct: 365 VLQQSVLEVDERGTEAVSGTLSEIIAYSMPPAIKV--NRPFHFIIYEEMSRMLLFLGRVV 422 Query: 472 NP 473 NP Sbjct: 423 NP 424 >2VDY-A nrPDB Length = 373 Score = 75.9 bits (185), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 90/375 (24%), Positives = 156/375 (41%), Gaps = 23/375 (6%) Query: 105 GFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTSR 164 F +YK L A S +SP ++ L LG+ T +QL L + E T Sbjct: 15 AFSLYKHL-VALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETEI 73 Query: 165 LDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLALF--TP 222 G + L L A S T L ++ LF L SF + + + Sbjct: 74 HQGFQHLHQLFA-----------KSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESE 122 Query: 223 ALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMRGF 282 L D +T A+ +IN ++K T K+ G+ + + L+ Y+ F+GT Sbjct: 123 VLAMNFQDWAT----ASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQP 178 Query: 283 SQLPGVHE--FWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATLLLIQPHC 340 L E F+VD + V VPM+ + + D++ + + T+ I P Sbjct: 179 FDLASTREENFYVDETTVVKVPMMLQSSTISYLHDSELPCQLVQMNYVGNGTVFFILPD- 237 Query: 341 TSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEA 400 ++ V A + R+ + W + L +P++ I G Y+L D+L E + L +A Sbjct: 238 KGKMNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTTQA 297 Query: 401 NLSNIG-DTNPRVGEVLNSILLEL-KAGEEEQPTTSVQQPGSPEALDVTLSSPFLFAIYE 458 N S I D + +V++ +L+L + G E ++ + + + + PF+ I++ Sbjct: 298 NFSRITQDAQLKSSKVVHKAVLQLNEEGTEAAGAMFLEAIPRSKPIILRFNQPFIIMIFD 357 Query: 459 QDSGTLHFLGRVNNP 473 + + FL RV NP Sbjct: 358 HFTWSSLFLARVMNP 372 >3DY0-A nrPDB Length = 336 Score = 73.6 bits (179), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 58/228 (25%), Positives = 106/228 (46%), Gaps = 8/228 (3%) Query: 200 GLFTAPGFRLKHSFVQSL-ALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPL 258 LFT L+ +FV ++ L+ FP + D A ++IN ++ T K+ L Sbjct: 96 ALFTDLVVDLQDTFVSAMKTLYLADTFPTNF---RDSAGAMKQINDYVAKQTKGKIVDLL 152 Query: 259 EGVSTDSTLLFNTYVHFQGTMRGFSQLPGVHE--FWVDNSISVSVPMISGTGNFQHWSDA 316 + + +++ ++ Y+ F+ G E F+V + V VPM+S + + D Sbjct: 153 KNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSREDQYHYLLDR 212 Query: 317 QNNFSVTCVPLGERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLE 376 + V VP AT L I P + +VE + L W++ R + L LP+ Sbjct: 213 NLSCRVVGVPYQGNATALFILP-SEGKMQQVENGLSEKTLRKWLKMFKKRQLELYLPKFS 271 Query: 377 IRGSYNLQDLLAEDKLPTLLGAEANLSNIGD-TNPRVGEVLNSILLEL 423 I GSY L+ +L + + + A+LS I + +N +V E+++ ++E+ Sbjct: 272 IEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEV 319 >4Y40-A nrPDB Length = 414 Score = 71.6 bits (174), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 57/242 (23%), Positives = 115/242 (47%), Gaps = 7/242 (2%) Query: 237 LATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMRGFSQLPGV---HEFWV 293 +A ++IN FI T K+N +E + + +L Y+ F+ + P V +F++ Sbjct: 172 MAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFD-PNVTKEEDFFL 230 Query: 294 DNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATLLLIQPHCTSDLDRVEALIFR 353 + + SV VPM+ +G +Q D + + ++ +P + T + I P L +E + Sbjct: 231 EKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPD-EGKLKHLEKGLQV 289 Query: 354 NDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNIG-DTNPRV 412 + W R + +++P+L + G+++L+ L+ + + +L+ I + +V Sbjct: 290 DTFSRWKTLLSRRVVCVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKV 349 Query: 413 GEVLNSILLEL-KAGEEEQPTTSVQQPGSPEALDVTLSSPFLFAIYEQDSGTLHFLGRVN 471 GE ++ L++ + G E T Q L V + P+L IY + ++ FLG++ Sbjct: 350 GEAVHKAELKMDERGTEGAAGTGAQTLPMETPLCVKIDKPYLLLIYSEKIPSVLFLGKIV 409 Query: 472 NP 473 NP Sbjct: 410 NP 411 >3NE4-A nrPDB Length = 424 Score = 70.1 bits (170), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 67/281 (23%), Positives = 132/281 (46%), Gaps = 13/281 (4%) Query: 200 GLFTAPGFRLKHSFVQSLA-LFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPL 258 GLF + G +L F++ + L+ F + D A ++IN +++ T K+ + Sbjct: 147 GLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFG---DTEEAKKQINDYVEKGTQGKIVDLV 203 Query: 259 EGVSTDSTLLFNTYVHFQGTMRGFSQLPGVHE--FWVDNSISVSVPMISGTG--NFQHWS 314 + + D+ Y+ F+G ++ E F VD +V VPM+ G N QH Sbjct: 204 KELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCK 263 Query: 315 DAQNNFSVTCVPLGERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQ 374 +++ + LG AT + P L +E + + + ++EN R+ L LP+ Sbjct: 264 KL-SSWVLLMKYLG-NATAIFFLPD-EGKLQHLENELTHDIITKFLENEDRRSASLHLPK 320 Query: 375 LEIRGSYNLQDLLAEDKLPTLLGAEANLSNIGDTNP-RVGEVLNSILLEL-KAGEEEQPT 432 L I G+Y+L+ +L + + + A+LS + + P ++ + ++ +L + + G E Sbjct: 321 LSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGA 380 Query: 433 TSVQQPGSPEALDVTLSSPFLFAIYEQDSGTLHFLGRVNNP 473 ++ +V + PF+F + EQ++ + F+G+V NP Sbjct: 381 MFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 421 >3ZHA-A nrPDB Length = 392 Score = 69.7 bits (169), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 47/189 (24%), Positives = 95/189 (50%), Gaps = 7/189 (3%) Query: 291 FWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGER-ATLLLIQPHCTSDLDRVEA 349 F V S +V V M+ TG + ++ D + + +PL + ++L+++ PH L+R+E Sbjct: 190 FMVTRSYTVGVTMMHRTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEK 249 Query: 350 LIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGA-EANLSNI-GD 407 L+ + L W+ +A+ ++LP+ + +++LQ LA L + +A+LS + G Sbjct: 250 LLTKEQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGK 309 Query: 408 TNPRVGEVLNSILLEL--KAGEEEQPTTSVQQPGSPEALDVTLSSPFLFAIYEQDSGTLH 465 + + V ++ E + +Q ++ SP+ PF+F + + SG+L Sbjct: 310 KDLYLASVFHATAFEWDTEGNPFDQDIYGREELRSPKLF--YADHPFIFLVRDTQSGSLL 367 Query: 466 FLGRVNNPQ 474 F+GR+ P+ Sbjct: 368 FIGRLVRPK 376 >1JMJ-A nrPDB Length = 480 Score = 69.3 bits (168), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 61/246 (24%), Positives = 111/246 (45%), Gaps = 8/246 (3%) Query: 233 TDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGT-MRGF-SQLPGVHE 290 +DP ++ N +K G + LE + + ++ ++F+G+ + F ++ H Sbjct: 235 SDPAFISKTNNHIMKLTKGL-IKDALENIDPATQMMILNCIYFKGSWVNKFPVEMTHNHN 293 Query: 291 FWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATLLLIQPHCTSDLDRVEAL 350 F ++ V V M+ GNF +D + + + + ++L++ PH S + +EA Sbjct: 294 FRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHKMSGMKTLEAQ 353 Query: 351 IFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNIGDTNP 410 + + W ++ R + LP+ ++ +YNL + L + L N++ I D Sbjct: 354 LTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNGNMAGISD--Q 411 Query: 411 RVGEVLNSILLELKAGEEEQPTTSVQQPG-SPEALDV--TLSSPFLFAIYEQDSGTLHFL 467 R+ L + EE T+V G P + V T+ PFLF IYE + L F+ Sbjct: 412 RIAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIYEHRTSCLLFM 471 Query: 468 GRVNNP 473 GRV NP Sbjct: 472 GRVANP 477 >2V95-A nrPDB Length = 371 Score = 68.2 bits (165), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 65/298 (21%), Positives = 139/298 (46%), Gaps = 26/298 (8%) Query: 189 SQTPLLQSIMVGLFTAPGFRLKHSFVQSLALF--TPALFPRSLDLSTDPVLATEKINRFI 246 S T L ++ +F +LK SF+ + + + AL ++D D A+++IN+ + Sbjct: 86 SDTGLEMNMGNAMFLLQKLKLKDSFLADVKQYYESEAL---AIDFE-DWTKASQQINQHV 141 Query: 247 KAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMRGFSQLP------GVHEFWVDNSISVS 300 K T K+ + + ++ + Y+ +RG +LP +F+V+ + +V Sbjct: 142 KDKTQGKIEHVFSDLDSPASFILVNYIF----LRGIWELPFSPENTREEDFYVNETSTVK 197 Query: 301 VPMISGTGNFQHWSDAQNNFSVTCVPLGERATLLLIQPHCTSDLDRVEALIFRNDLLTWI 360 VPM+ +G+ ++ D+ + + T I P +D V A + R+ + W Sbjct: 198 VPMMVQSGSIGYFRDSVFPCQLIQMDYVGNGTAFFILPD-QGQMDTVIAALSRDTIDRWG 256 Query: 361 ENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNIGDTNPRVGEVLNSIL 420 + PR + L +P+ + +Y+L+D+L + + LL +++ S P +++ + Sbjct: 257 KLMTPRQVNLYIPKFSMSDTYDLKDVLEDLNIKDLLTNQSDFSGNTKDVPLTLTMVHKAM 316 Query: 421 LELKAGEEEQPTTSVQQPGSP-----EALDVTLSSPFLFAIYEQDSGTLHFLGRVNNP 473 L+L G +T+ G+P E LD+ + PF+ ++++ + + + +V NP Sbjct: 317 LQLDEGNVLPNSTN----GAPLHLRSEPLDIKFNKPFILLLFDKFTWSSLMMSQVVNP 370 >6HGE-B nrPDB Length = 409 Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 98/409 (23%), Positives = 174/409 (42%), Gaps = 31/409 (7%) Query: 81 LAAEKLEDEDRKRAAQVAM---IANF-VGFRMYKMLNEAGSGASGAILSPPALFGTLVSF 136 L E L E++ R V AN F +YK L + I SP ++ L Sbjct: 15 LDEENLTQENQDRGTHVDRGLASANVDFAFSLYKQL-VLKAPDKNVIFSPLSISTALAFL 73 Query: 137 YLGSLDPTASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQS 196 LG+ + T +++ L + E TS + H+ + Q LL T SS + L S Sbjct: 74 SLGAHNTTLTEILKGLKFNLTE---TSEAEIHQ------SFQHLLRTLNQSSDELQL--S 122 Query: 197 IMVGLFTAPGFRLKHSFVQSLA-LFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMN 255 + +F L F + L+ F D A + IN ++K T K+ Sbjct: 123 MGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQ---DSAAAKKLINDYVKNGTRGKIT 179 Query: 256 LPLEGVSTDSTLLFNTYVHFQGTMRGFSQLPGVHE--FWVDNSISVSVPMISGTG-NFQH 312 ++ + + + ++ Y+ F+ H+ F++ V VPM+S + Sbjct: 180 DLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMSLHHLTIPY 239 Query: 313 WSDAQNNFSVTCVPLGERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAI-RLT 371 + D + + +V + A+ L I P ++ VEA++ R L W ++ R I L Sbjct: 240 FRDEELSCTVVQLNYTGNASALFILPD-QDKMEEVEAMLSRETLNRWGDSLEFREIGELY 298 Query: 372 LPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNI-GDTNPRVGEVLNSILLEL-KAGEEE 429 LP+ I YNL D+L + + ++A+LS I G N V +V++ +L++ + G E Sbjct: 299 LPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGTEA 358 Query: 430 QPTTSVQQPGSPEALD----VTLSSPFLFAIYEQDSGTLHFLGRVNNPQ 474 T+V+ ++ V + PFL I + + ++ F+ +V NP+ Sbjct: 359 SAATAVKITLLSALVETRTIVRFNRPFLMIIVDHFTWSIFFMSKVTNPK 407 >4ZK0-A nrPDB Length = 390 Score = 66.2 bits (160), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 85/375 (22%), Positives = 165/375 (44%), Gaps = 24/375 (6%) Query: 117 SGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTSRLDGHKVLAA--- 173 S + SP ++ L LG+ D TA Q++ +L + T + + V + Sbjct: 22 SKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQVTENTTGKAATYHVDRSGNV 81 Query: 174 LRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLALFTPALFPRSLDLST 233 Q LL S+ L I LF + ++ ++ F S+D + Sbjct: 82 HHQFQKLLTEFNKSTDAYEL--KIANKLFGEKTYLFLQEYLDAIKKFYQTSV-ESVDFAN 138 Query: 234 DPVLATEKINRFIKAVTGWKM-NLPLEG-VSTDSTLLFNTYVHFQGTM-RGFSQLPGVHE 290 P + +KIN ++++ T K+ NL EG + +++TL+ ++F+G + F++ E Sbjct: 139 APEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYFKGQWEKKFNKEDTKEE 198 Query: 291 -FWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPL-GERATLLLIQPHCTSDLDRVE 348 FW + + S+ M+ +F S V +P G+ +++++ P+ L ++E Sbjct: 199 KFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQKLE 258 Query: 349 ALIFRNDLLTW--IENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNIG 406 + L+ W ++N + L LP+ ++ SY+L+D L + + +A+LS G Sbjct: 259 EKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLRTMGMVDIFNGDADLS--G 316 Query: 407 DTNPRVGEVLNSILLELKAGEEEQPTTSVQQP------GSPEALDVTL--SSPFLFAIYE 458 T R G VL+ +L + E+ + SP + + + PFLF I + Sbjct: 317 MTGSR-GLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTSTNEEFHCNHPFLFFIRQ 375 Query: 459 QDSGTLHFLGRVNNP 473 + ++ F GR ++P Sbjct: 376 NKTNSILFYGRFSSP 390 >4AJU-A nrPDB Length = 387 Score = 61.6 bits (148), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 74/337 (21%), Positives = 138/337 (40%), Gaps = 29/337 (8%) Query: 96 QVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDV- 154 Q+A + GF + + ++ G + SP + + LG+ PT +Q++ L + Sbjct: 53 QLAKETSNFGFSLLRKISMRHDG--NMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQ 110 Query: 155 ---PVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKH 211 P K G S G + + GL TQG + F F +K Sbjct: 111 ALKPTKPGLLPSLFKGLRETLSRNLELGL--TQGSFA-------------FIHKDFDVKE 155 Query: 212 SFVQ-SLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFN 270 +F S F P + ++ A +N +I T K+ + ++ ++ L+ Sbjct: 156 TFFNLSKRYFDTECVPMNFRNASQ---AKRLMNHYINKETRGKIPKLFDEINPETKLILV 212 Query: 271 TYVHFQGT-MRGFSQL-PGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLG 328 Y+ F+G + F + V F +D ++ VPM+ G G F D V +P Sbjct: 213 DYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQ 272 Query: 329 ERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLA 388 AT+L++ D +E + + + TW+ N R + + P+ ++ Y + +LL Sbjct: 273 GNATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLR 332 Query: 389 EDKLPTLLGAEANLSNIGDT--NPRVGEVLNSILLEL 423 + + + A+LS + T N +V VL ++E+ Sbjct: 333 QMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEV 369 >1C8O-A nrPDB Length = 300 Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 74/324 (22%), Positives = 133/324 (41%), Gaps = 51/324 (15%) Query: 111 MLNEAGSGASG--AILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPV-KEGDCTSRLDG 167 + E S G +SPP++ L Y G+ TA QL ++ K D S Sbjct: 3 IFREIASSMKGENVFISPPSISSVLTILYYGANGSTAEQLSKYVEKEADKNKDDISFKSM 62 Query: 168 HKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLAL-FTPALFP 226 +KV AV K SF++ + F F Sbjct: 63 NKVYGRYSAV-------------------------------FKDSFLRKIGDNFQTVDFT 91 Query: 227 RSLDLSTDPVLATEKINRFIKAVTGWKMNLPL--EGVSTDSTLLFNTYVHFQGT--MRGF 282 S + IN+ + T K+N PL E +S D++LL + V+F+ M Sbjct: 92 DSR--------TVDAINKSVDIFTEGKIN-PLLDEPLSPDTSLLAISAVYFKAKWLMPFE 142 Query: 283 SQLPGVHEFWVDNSISVSVPMISGTGN-FQHWS--DAQNNFSVTCVPLGERATLLLIQPH 339 + + F+V + V V M+S G F H S ++ NFS+ +P ++++I P Sbjct: 143 KEFTSDYPFYVSPTEMVDVSMMSMYGEAFNHASVKESFGNFSIIELPYVGDTSMVVILPD 202 Query: 340 CTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAE 399 L+ +E + + W ++ I + +P+ ++ GSYNL D L + L + G+ Sbjct: 203 NIDGLESIEQNLTDTNFKKWSDSMDAMFIDVHIPKFKVTGSYNLVDALVKLGLTEVFGST 262 Query: 400 ANLSNIGDTNPRVGEVLNSILLEL 423 + SN+ +++ V +++ +++ Sbjct: 263 GDYSNMSNSDVSVDAMIHKTYIDV 286 >1IMV-A nrPDB Length = 398 Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 92/391 (23%), Positives = 176/391 (45%), Gaps = 44/391 (11%) Query: 98 AMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVK 157 A ++NF G+ +Y++ + S + +LSP ++ L + LG+ + T S + L Sbjct: 36 AAVSNF-GYDLYRV-RSSMSPTTNVLLSPLSVATALSALSLGADERTESIIHRALYY--- 90 Query: 158 EGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSL 217 D S D H L + + Q L+S +F R+K SFV L Sbjct: 91 --DLISSPDIHGTYKEL--LDTVTAPQKN-------LKSASRIVFEK-KLRIKSSFVAPL 138 Query: 218 ALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQG 277 + R L+ +P L ++IN +++A K+ + + + ++L HF+G Sbjct: 139 E---KSYGTRPRVLTGNPRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKG 195 Query: 278 --TMRGFSQLPGVHEFWVDNSISVSVPMISG-TGNFQHWSDAQNNFSVTCVPLGERATLL 334 + S+ + +F++D +V VPM+S ++ D+ + + +PL +++ Sbjct: 196 QWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSII 255 Query: 335 LIQP-HCTSDLDRVEALI---FRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAED 390 P T +L +E + F +D+ ++ +A+ LT+P+L++ + L E Sbjct: 256 FFLPLKVTQNLTLIEESLTSEFIHDIDRELKTV--QAV-LTVPKLKLSYEGEVTKSLQEM 312 Query: 391 KLPTLLGAEANLSNIGDTNPRVGEVLNSILLELKAGEE--EQPTTSVQQPGSPEA----- 443 KL +L + + S I G+ + +E +AG E E + PG A Sbjct: 313 KLQSLFDS-PDFSKI------TGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFP 365 Query: 444 LDVTLSSPFLFAIYEQDSGTLHFLGRVNNPQ 474 LD L+ PF+F + + D+G L F+G++ +P+ Sbjct: 366 LDYHLNQPFIFVLRDTDTGALLFIGKILDPR 396 >1M93-B nrPDB Length = 245 Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 48/191 (25%), Positives = 96/191 (50%), Gaps = 8/191 (4%) Query: 240 EKINRFIKAVTGWKMNLPL--EGVSTDSTLLFNTYVHFQGT--MRGFSQLPGVHEFWVDN 295 + IN+ + T K+N PL E +S D++LL + V+F+ M + + F+V Sbjct: 42 DAINKSVDIFTEGKIN-PLLDEPLSPDTSLLAISAVYFKAKWLMPFEKEFTSDYPFYVSP 100 Query: 296 SISVSVPMISGTGN-FQHWS--DAQNNFSVTCVPLGERATLLLIQPHCTSDLDRVEALIF 352 + V V M+S G F H S ++ NFS+ +P ++++I P L+ +E + Sbjct: 101 TEMVDVSMMSMYGEAFNHASVKESFGNFSIIELPYVGDTSMVVILPDNIDGLESIEQNLT 160 Query: 353 RNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNIGDTNPRV 412 + W ++ I + +P+ ++ GSYNL D L + L + G+ + SN+ +++ V Sbjct: 161 DTNFKKWSDSMDAMFIDVHIPKFKVTGSYNLVDALVKLGLTEVFGSTGDYSNMSNSDVSV 220 Query: 413 GEVLNSILLEL 423 +++ +++ Sbjct: 221 DAMIHKTYIDV 231 >4KDS-A nrPDB Length = 386 Score = 59.7 bits (143), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 85/332 (25%), Positives = 142/332 (42%), Gaps = 29/332 (8%) Query: 167 GHKVLAALRAVQGLLVTQGGSSSQTPLLQ---------SIMVGLFTAPGFRLKHSFVQSL 217 G L L A G + + G + Q LLQ + G+ L+ F + L Sbjct: 58 GGNTLKTLNAKLGFSLQERGMARQQRLLQRDISSEEGVELASGVMVERKMALEKGFRRGL 117 Query: 218 ALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKM-NLPLEGVSTDST--LLFNTYVH 274 A P LD S P A + IN ++ T + + G TD T +L N +H Sbjct: 118 GKAFQA-SPHQLDFSR-PDQALDIINAWVSDHTAGTIPSFLSSGALTDETRMVLLNA-LH 174 Query: 275 FQGTMR-GFSQLPGVHE---FWVDNSISVSVPMISGTGNFQHWSDAQ---NNFSVTCVPL 327 FQG + F P + E F N SV VPM+ T F++ ++ V VP Sbjct: 175 FQGLWKVPFD--PKMTEERLFHCANGSSVPVPMMRLTHRFKYGEFVTPDGVDYDVIEVPY 232 Query: 328 -GERATLLLIQP-HCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQD 385 GE ++LL+ P + + + + + L W + +L LP+ + L+ Sbjct: 233 EGESLSMLLVSPFEPETPVSSLSSELTTQRLQQWRQEMRSVKRQLVLPRFTLDSEVELKS 292 Query: 386 LLAEDKLPTLLG-AEANLSNIGDTNPR-VGEVLNSILLEL-KAGEEEQPTTSVQQPGSPE 442 +L + L + A+A+ + I P V +VL + +E+ + G + T+ Sbjct: 293 ILIQMGLGDMFNLAKADFTRITTEQPLCVSKVLQKVKIEVNEEGTKASAATAAILFSRMA 352 Query: 443 ALDVTLSSPFLFAIYEQDSGTLHFLGRVNNPQ 474 ++T++ PFLF I+ + +G + F+G+VN PQ Sbjct: 353 VEEITMNRPFLFLIHHKSTGAVLFMGQVNQPQ 384 >1UHG-A nrPDB Length = 385 Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 81/366 (22%), Positives = 153/366 (41%), Gaps = 29/366 (7%) Query: 126 PPALFGTLVSFYLGSLDPTASQLQTLLDVP-------VKEGDCTSRLDGHKVLAALRAVQ 178 P A+ L YLG+ D T +Q+ ++ E C + ++ H ++LR + Sbjct: 31 PIAIMSALAMVYLGAKDSTRTQINKVVRFDKLPGFGDSIEAQCGTSVNVH---SSLRDIL 87 Query: 179 GLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLA-LFTPALFPRSLDLSTDPVL 237 + S S+ L+ + + ++Q + L+ L P + + D Sbjct: 88 NQITKPNDVYSF-----SLASRLYAEERYPILPEYLQCVKELYRGGLEPINFQTAADQ-- 140 Query: 238 ATEKINRFIKAVTGWKMNLPLEGVSTDS---TLLFNTYVHFQGTM-RGFS-QLPGVHEFW 292 A E IN ++++ T + L+ S DS +L N V F+G + F + F Sbjct: 141 ARELINSWVESQTNGIIRNVLQPSSVDSQTAMVLVNAIV-FKGLWEKAFKDEDTQAMPFR 199 Query: 293 VDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGE-RATLLLIQPHCTSDLDRVEALI 351 V S V M+ G F+ S A + +P ++L++ P S L+++E++I Sbjct: 200 VTEQESKPVQMMYQIGLFRVASMASEKMKILELPFASGTMSMLVLLPDEVSGLEQLESII 259 Query: 352 FRNDLLTWIENP--PPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNIGDTN 409 L W + R I++ LP++++ YNL +L + + + ANLS I Sbjct: 260 NFEKLTEWTSSNVMEERKIKVYLPRMKMEEKYNLTSVLMAMGITDVFSSSANLSGISSAE 319 Query: 410 P-RVGEVLNSILLEL-KAGEEEQPTTSVQQPGSPEALDVTLSSPFLFAIYEQDSGTLHFL 467 ++ + +++ E+ +AG E + + + + PFLF I + + F Sbjct: 320 SLKISQAVHAAHAEINEAGREVVGSAEAGVDAASVSEEFRADHPFLFCIKHIATNAVLFF 379 Query: 468 GRVNNP 473 GR +P Sbjct: 380 GRCVSP 385 >1YXA-A nrPDB Length = 398 Score = 57.4 bits (137), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 59/249 (23%), Positives = 115/249 (46%), Gaps = 10/249 (4%) Query: 235 PVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMR-GFSQLPGVH-EFW 292 P A + IN +++ T + + + + ++ Y++F+ + F L EF+ Sbjct: 151 PRQAKKLINDYVRKQTQGMIKELVSDLDKRTLMVLVNYIYFKAKWKVPFDPLDTFKSEFY 210 Query: 293 VDNSISVSVPMISGTG-NFQHWSDAQNNFSVTCVPLGERATLLLIQPHCTSDLDRVEALI 351 V VPM+S ++ D + + +V + A+ L I P + +VEA + Sbjct: 211 CGKRRPVIVPMMSMEDLTTPYFRDEELSCTVVELKYTGNASALFILPD-QGRMQQVEASL 269 Query: 352 FRNDLLTWIENPPPRAI-RLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNI-GDTN 409 L W + PR I L LP+ I Y+L+D+L++ + + +A+LS I G + Sbjct: 270 QPETLRKWKNSLKPRMIDELHLPKFSISTDYSLEDVLSKLGIREVFSTQADLSAITGTKD 329 Query: 410 PRVGEVLNSILLELKAGEEEQPTTSVQQ--PGSPEA--LDVTLSSPFLFAIYEQDSGTLH 465 RV +V++ +L++ E + + P S + L V + PFL I++ ++ Sbjct: 330 LRVSQVVHKAVLDVAETGTEAAAATGVKFVPMSAKLYPLTVYFNRPFLIMIFDTETEIAP 389 Query: 466 FLGRVNNPQ 474 F+ ++ NP+ Sbjct: 390 FIAKIANPK 398 >4EB1-I nrPDB Length = 440 Score = 52.8 bits (125), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 62/265 (23%), Positives = 114/265 (43%), Gaps = 20/265 (7%) Query: 229 LDLSTDPVLATEKINRFIKAVTGWKMN--LPLEGVS--------TDSTLLFNTYVHFQGT 278 LD + + IN+++ T ++ +P E ++ T + L+ ++F+G Sbjct: 173 LDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINVLVLVNTRTSTVLVLVNTIYFKGL 232 Query: 279 MRG-FSQLPGVHE-FWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATLLLI 336 + FS E F+ + S S M+ G F++ A+ + G+ T++LI Sbjct: 233 WKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAEGTQVLELPFKGDDITMVLI 292 Query: 337 QPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLL 396 P L +VE + L W++ + + +P+ I ++L++ L + L L Sbjct: 293 LPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLF 352 Query: 397 GAE-ANLSNI---GDTNPRVGEVLNSILLEL-KAGEEEQPTTSVQQPG---SPEALDVTL 448 E + L I G + V + + LE+ + G E +T+V G +P + Sbjct: 353 SPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKA 412 Query: 449 SSPFLFAIYEQDSGTLHFLGRVNNP 473 + PFL I E T+ F+GRV NP Sbjct: 413 NRPFLVFIREVPLNTIIFMGRVANP 437 >1QMB-A nrPDB Length = 326 Score = 52.8 bits (125), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 53/216 (24%), Positives = 99/216 (45%), Gaps = 12/216 (5%) Query: 200 GLFTAPGFRLKHSFVQSLA-LFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPL 258 GLF + G +L F++ + L+ F + D A ++IN +++ T K+ + Sbjct: 92 GLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFG---DTEEAKKQINDYVEKGTQGKIVDLV 148 Query: 259 EGVSTDSTLLFNTYVHFQGTMRGFSQLPGVHE--FWVDNSISVSVPMISGTG--NFQHWS 314 + + D+ Y+ F+G ++ E F VD +V VPM+ G N QH Sbjct: 149 KELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCK 208 Query: 315 DAQNNFSVTCVPLGERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQ 374 +++ + LG AT + P L +E + + + ++EN R+ L LP+ Sbjct: 209 KL-SSWVLLMKYLG-NATAIFFLPD-EGKLQHLENELTHDIITKFLENDR-RSASLHLPK 264 Query: 375 LEIRGSYNLQDLLAEDKLPTLLGAEANLSNIGDTNP 410 L I G+Y+L+ +L + + + A+LS + + P Sbjct: 265 LSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAP 300 >1BY7-A nrPDB Length = 382 Score = 52.4 bits (124), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 84/395 (21%), Positives = 167/395 (42%), Gaps = 39/395 (9%) Query: 100 IAN-FVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKE 158 +AN ++K L +A S LSP ++ T+ Y+GS T Q+ +L Sbjct: 6 VANTLFALNLFKHLAKA-SPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF---- 60 Query: 159 GDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLA 218 + + D K+ ++ R++ + +S+ LL+S+ LF + +++ Sbjct: 61 NEVGAAAD--KIHSSFRSLSSAI----NASTGNYLLESVN-KLFGEKSASFREEYIRLCQ 113 Query: 219 LFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKM-NLPLEG-VSTDSTLLFNTYVHFQ 276 + + P+++D A +KIN ++K T K+ NL EG V D+ ++ V+F+ Sbjct: 114 KYYSSE-PQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSVDGDTRMVLVNAVYFK 172 Query: 277 GTMRG--FSQLPGVHEFWVDNSISVSVPM--ISGTGNFQHWSDAQNNFSVTCVPLGERAT 332 G + +L G++ F V+++ V M + N + D + + +P + Sbjct: 173 GKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLKAQ--ILELPYAGDVS 230 Query: 333 LLLIQPHCTSD----LDRVEALIFRNDLLTWI--ENPPPRAIRLTLPQLEIRGSYNLQDL 386 + L+ P +D L+ +E+ I + L W + + + +PQ ++ Y L+ + Sbjct: 231 MFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEVYIPQFKLEEHYELRSI 290 Query: 387 LAEDKLPTLLG-AEANLSNIGDTNPR-VGEVLNSILLELKAGEEEQPT------TSVQQP 438 L + AN S + + N + EV + ++++ E T Sbjct: 291 LRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEGTEAAAGTGGVMTGRTGH 350 Query: 439 GSPEALDVTLSSPFLFAIYEQDSGTLHFLGRVNNP 473 G P+ PFLF I + + + F GR ++P Sbjct: 351 GGPQ---FVADHPFLFLIMHKITNCILFFGRFSSP 382 >4DTE-A nrPDB Length = 374 Score = 52.0 bits (123), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 64/261 (24%), Positives = 114/261 (43%), Gaps = 13/261 (4%) Query: 226 PRSLDLSTDPVLATEKINRFIKAVTGWKMN--LPLEGVSTDSTLLFNTYVHFQGTMRGFS 283 P +D S P +A + IN + T ++ LP +S + L+F +HF G + Sbjct: 113 PHQIDFS-QPEMARQVINSWTSDHTDGMISEFLPSGVLSELTRLVFLNALHFHGVWKTPF 171 Query: 284 QLPGVHE--FWVDNSISVSVPMISGTGNFQHW---SDAQNNFSVTCVPL-GERATLLLIQ 337 E F N +VSVPM++ T F + S ++ V +P GE ++LL+ Sbjct: 172 DPRNTREQLFHTVNGSAVSVPMMTTTQKFNYGEFVSKDGVDYDVIEMPYEGESISMLLVT 231 Query: 338 PHCTS-DLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLL 396 P L + + + + W + + +L++P+ + +L+ L+ L + Sbjct: 232 PFEKDVPLSALNKELSSSRIHQWRQEMRKISKQLSIPRFSMDTEIDLKSTLSRMGLGDIF 291 Query: 397 G-AEANLSNIGDTNPR-VGEVLNSILLEL-KAGEEEQPTTSVQQPGSPEALDVTLSSPFL 453 + A+ S I P V +VL + LE+ + G + T+ ++TL PF Sbjct: 292 SQSRADFSRITTEEPLCVSKVLQRVKLEVNEEGTKGSSATAAVIYSRMAVEEITLDRPFF 351 Query: 454 FAIYEQDSGTLHFLGRVNNPQ 474 F I + +G L F G++ PQ Sbjct: 352 FLIQHKPTGALLFSGQLTQPQ 372 >1ATT-A nrPDB Length = 429 Score = 51.6 bits (122), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 80/379 (21%), Positives = 157/379 (41%), Gaps = 24/379 (6%) Query: 108 MYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTSRLDG 167 Y+ L ++ + LSP ++ LG+ + T +QL + V + D S Sbjct: 59 FYQHLADSKNNNDNIFLSPLSISTAFAMTKLGACNNTLTQL-----MEVFKFDTISEKTS 113 Query: 168 HKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQ-SLALFTPALFP 226 ++ + L + SS+ LF ++ S ++ L P Sbjct: 114 DQIHFFFAKLNCRLYRKANKSSELVSANR----LFGDKSITFNETYQDISEVVYGAKLQP 169 Query: 227 RSLDLSTDPVLATEKINRFIKAVTGWKMN--LPLEGVSTDSTLLFNTYVHFQGTMRG-FS 283 LD + + IN++I T ++ +P + ++ + L+ ++F+G + FS Sbjct: 170 --LDFKGNAEQSRLTINQWISNKTEGRITDVIPPQAINEFTVLVLVNTIYFKGLWKSKFS 227 Query: 284 QLPGVHE-FWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATLLLIQPHCTS 342 E F+ + S SV M+ F++ A++ + G+ T++LI P Sbjct: 228 PENTRKELFYKADGESCSVLMMYQESKFRYRRVAESTQVLELPFKGDDITMVLILPKLEK 287 Query: 343 DLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAE-AN 401 L +VE + + L W++ + + +P+ I S+++++ L + L L E + Sbjct: 288 TLAKVEQELTPDMLQEWLDELTETLLVVHMPRFRIEDSFSVKEQLQDMGLEDLFSPEKSR 347 Query: 402 LSNI---GDTNPRVGEVLNSILLEL-KAGEEEQPTTSVQQPG---SPEALDVTLSSPFLF 454 L I G ++ V + + LE+ + G E +T + G + + + + PFL Sbjct: 348 LPGIVAEGRSDLYVSDAFHKAFLEVNEEGSEAAASTVISIAGRSLNSDRVTFKANRPFLV 407 Query: 455 AIYEQDSGTLHFLGRVNNP 473 I E T+ F+GRV NP Sbjct: 408 LIREVALNTIIFMGRVANP 426 >2R9Y-A nrPDB Length = 430 Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 101/395 (25%), Positives = 153/395 (38%), Gaps = 45/395 (11%) Query: 89 EDRKRAAQVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQL 148 E+ +R AQ M F + S +S +LSP ++ L LG+ + T L Sbjct: 16 EETRRLAQAMMAFTTDLFSLVAQ----TSTSSNLVLSPLSVALALSHLALGAQNQTLHSL 71 Query: 149 QTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFR 208 +L + G C L H Q L P + ++ GF Sbjct: 72 HRVLHM--NTGSCLPHLLSH-------FYQNL----------GPGTIRLAARIYLQKGFP 112 Query: 209 LKHSFV-QSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTL 267 +K F+ QS LF P L + LA IN+++K T K+ L + + L Sbjct: 113 IKDDFLEQSERLFGAK--PVKLTGKQEEDLAN--INQWVKEATEGKIEDFLSELPDSTVL 168 Query: 268 LFNTYVHFQGTMR-GFS-QLPGVHEFWVDNSISVSVPMISGTGNFQHWSD-AQNNFSVTC 324 L +HF G R F L F +D +VSV M+ W Q V Sbjct: 169 LLLNAIHFHGFWRTKFDPSLTQKDFFHLDERFTVSVDMMHAVSYPLRWFLLEQPEIQVAH 228 Query: 325 VPLGERATLLLIQP-HCTSDLDRVEALIFRNDLLTW--IENPP--PRAIRLTLPQLEIRG 379 P + +++ P + ++ V A LTW + +P R ++ LP+L ++ Sbjct: 229 FPFKNNMSFVVVMPTYFEWNVSEVLAN------LTWDTLYHPSLQERPTKVWLPKLHLQQ 282 Query: 380 SYNLQDLLAEDKLPTLLGAEANLSNIGDTNPRVGEVLNSILLEL-KAGEEEQPTTSVQQP 438 +L L++ L L +L I + N V V + +EL +AG E TSV Sbjct: 283 QLDLVATLSQLGLQELFQG-PDLRGISEQNLVVSSVQHQSTMELSEAGVEAAAATSVAM- 340 Query: 439 GSPEALDVTLSSPFLFAIYEQDSGTLHFLGRVNNP 473 T++ PFLF I E G F+G V NP Sbjct: 341 NRMSLSSFTVNRPFLFFIMEDTIGVPLFVGSVRNP 375 >2OAY-A nrPDB Length = 390 Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 82/383 (21%), Positives = 167/383 (43%), Gaps = 44/383 (11%) Query: 105 GFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTSR 164 ++Y + + SP ++ L LG+ + T + L+++L P K+ C + Sbjct: 40 SLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYP-KDFTCVHQ 98 Query: 165 LDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQ-SLALFTPA 223 A++G S SQ +F +P ++ +FV S L++ + Sbjct: 99 -----------ALKGFTTKGVTSVSQ----------IFHSPDLAIRDTFVNASRTLYSSS 137 Query: 224 LFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMRG-F 282 PR L ++D L E IN ++ T K++ L+ + +D+ L+ ++ + F Sbjct: 138 --PRVLSNNSDANL--ELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTF 193 Query: 283 S-QLPGVHEFWVDNSISVSVPMISGTGN-FQHWSDAQNNFSVTCVPLGERATLLLIQP-- 338 + + F NS+ + VPM++ H+ D V + L +L+++ P Sbjct: 194 DPKKTRMEPFHFKNSV-IKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQN 252 Query: 339 --HCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLA-EDKLPTL 395 H D+++ + ++ +E + LTLP++++ S QD+L+ +KL Sbjct: 253 LKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTS---QDMLSIMEKLEFF 309 Query: 396 -LGAEANLSNIG-DTNPRVGEVLNSILLEL-KAGEEEQPTTSVQQPGSPEALDVTLSSPF 452 + NL + D + +V + + +LEL + G E +++ + +V PF Sbjct: 310 DFSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEV--QQPF 367 Query: 453 LFAIYEQDSGTLHFLGRVNNPQS 475 LF +++Q F+GRV +P++ Sbjct: 368 LFMLWDQQHKFPVFMGRVYDPRA 390 >3F02-A nrPDB Length = 359 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 51/238 (21%), Positives = 101/238 (42%), Gaps = 23/238 (9%) Query: 187 SSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKINRFI 246 ++ ++ + I LF GF + F+Q + + A +D S + +A IN+++ Sbjct: 95 TAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNH-VDFSQNVAVAN-YINKWV 152 Query: 247 KAVTGWKMNLPLEGVS-----TDSTLLFNTYVHFQGTMRGFSQL----PGVHEFWVDNSI 297 + T NL + VS + L V+F+G + SQ F D+ Sbjct: 153 ENNTN---NLVKDLVSPRDFDAATYLALINAVYFKGNWK--SQFRPENTRTFSFTKDDES 207 Query: 298 SVSVPMISGTGNFQH--WSDAQNN----FSVTCVPL-GERATLLLIQPHCTSDLDRVEAL 350 V +PM+ G F + +SD N + V +P G+ +++L+ L +E L Sbjct: 208 EVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEPL 267 Query: 351 IFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNIGDT 408 + + W + + + + LP+ + +L+D+L + + +ANL+ + D Sbjct: 268 VKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLTGLSDN 325 >2XN5-A nrPDB Length = 350 Score = 45.1 bits (105), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 37/175 (21%), Positives = 75/175 (42%), Gaps = 4/175 (2%) Query: 238 ATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMRG-F--SQLPGVHEFWVD 294 A ++IN ++ T K+ ++ + ++ ++ Y+HF+ F S+ F +D Sbjct: 138 AKQEINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLID 197 Query: 295 NSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATLLLIQPHCTSDLDRVEALIFRN 354 + +V VPM+ + H D + N +V + + A L + P ++ VEA + Sbjct: 198 KTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDYSKNALALFVLPK-EGQMESVEAAMSSK 256 Query: 355 DLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNIGDTN 409 L W + L +P+ I +Y+L L + + A+ S + + N Sbjct: 257 TLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDN 311 >1JJO-C nrPDB Length = 261 Score = 44.7 bits (104), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 49/220 (22%), Positives = 93/220 (42%), Gaps = 17/220 (7%) Query: 201 LFTAPGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTG--WKMNLPL 258 LF GF + F+Q L ++ A +D S + +A IN++++ T K + Sbjct: 12 LFVQNGFHVNEEFLQMLKMYFNAEVNH-VDFSQNVAVAN-SINKWVENYTNSLLKDLVSP 69 Query: 259 EGVSTDSTLLFNTYVHFQGTMRGFSQL----PGVHEFWVDNSISVSVPMISGTGNFQH-- 312 E + L V+F+G + SQ F D+ V +PM+ G F + Sbjct: 70 EDFDGVTNLALINAVYFKGNWK--SQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGE 127 Query: 313 WSDAQNN----FSVTCVPL-GERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRA 367 +SD N + V +P G+ +++L L +E L+ + W + + Sbjct: 128 FSDGSNEAGGIYQVLEIPYEGDEISMMLALSRQEVPLATLEPLLKAQLIEEWANSVKKQK 187 Query: 368 IRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNIGD 407 + + LP+ + +L+D+L + + +ANL+ + D Sbjct: 188 VEVYLPRFTVEQEIDLKDILKALGVTEIFIKDANLTAMSD 227 >3NDA-A nrPDB Length = 377 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 53/260 (20%), Positives = 112/260 (43%), Gaps = 24/260 (9%) Query: 228 SLDLSTDPVLATEKINRFIKAVTGWKM-NLPLEGVSTDSTLLFNTYVHFQGTMR-GFSQL 285 +D + +P A + +N ++K T K+ L E + D+ L+ ++F+G F + Sbjct: 124 KVDFAGEPQAAVDFVNNWVKRKTHDKIEKLFNEPLDPDTLLVLLNAIYFKGEWNTAFVKE 183 Query: 286 PGVHEFWVDNSIS---VSVPMISGTGNFQHWSDAQNNFSVTCVPLGERA---TLLLIQPH 339 + + ++ V + ++ + D Q V V L R T+ ++ P Sbjct: 184 HTEKRQFFNGGVTPVEVDTMRLEARIKYRFFDDLQ----VEVVELPYRGLDYTMAILLPK 239 Query: 340 CTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAE 399 + ++ ++ + + ++ + R I + LP+ ++ Y+L+ L + + + Sbjct: 240 ENTGVEGLKQNLTIDRFQNYLSDLRERKITVLLPKFKLETKYSLKAPLQSLGIKQIFESG 299 Query: 400 ANLSNIGDTNPRVGEVLNSILLELKAGEEEQPTTSVQQPG--------SPEALDVTLSSP 451 A+LS I D + RV V + ++E+ E+ T + G PE + + P Sbjct: 300 ADLSGINDGSLRVSAVEHKAVVEVN----EEGTVAAATTGVVIVPYSLGPEPVVFRVDHP 355 Query: 452 FLFAIYEQDSGTLHFLGRVN 471 FLF I + + F+G+VN Sbjct: 356 FLFFIRNTRTDDIFFVGQVN 375 >6F4U-A nrPDB Length = 341 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 75/316 (23%), Positives = 122/316 (38%), Gaps = 31/316 (9%) Query: 101 ANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGD 160 A+F FR Y ++ G + SP ++ LG+ + SQ+ L + E Sbjct: 10 ADF-AFRFYYLIASETPGKN-IFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTE-- 65 Query: 161 CTSRLDGHKVLAALRAVQGLLVTQG--GSSSQTPLLQSIMVGLFTAPGFRLKHSFVQ-SL 217 S D H R Q LL T G +T + LF + + F+ ++ Sbjct: 66 -LSESDVH------RGFQHLLHTLNLPGHGLET----RVGSALFLSHNLKFLAKFLNDTM 114 Query: 218 ALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQG 277 A++ LF + D V + IN +K T K+ + + D ++ Y++F+ Sbjct: 115 AVYEAKLFHTNF---YDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKA 171 Query: 278 TMRG--FSQLPGVHEFWVDNSISVSVPMISGTGNFQHW--SDAQNNFSVTCVPLGERATL 333 S +F+VD + +V VPM+ HW D SV + AT+ Sbjct: 172 LWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQE-HHWYLHDRYLPCSVLRMDYKGDATV 230 Query: 334 LLIQPHCTSDLDRVEALIFRNDLLTWIENPPPR----AIRLTLPQLEIRGSYNLQDLLAE 389 I P+ + +E ++ L+ W R + L LP+ I GSY L +L Sbjct: 231 FFILPN-QGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPR 289 Query: 390 DKLPTLLGAEANLSNI 405 L A+LS I Sbjct: 290 LGFTDLFSKWADLSGI 305 >6F02-A nrPDB Length = 389 Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 88/390 (22%), Positives = 147/390 (37%), Gaps = 45/390 (11%) Query: 105 GFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTSR 164 FR Y ++ G + SP ++ LG+ + SQ+ L + E S Sbjct: 15 AFRFYYLIASETPGKN-IFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTE---LSE 70 Query: 165 LDGHKVLAALRAVQGLLVTQG--GSSSQTPLLQSIMVGLFTAPGFRLKHSFVQ-SLALFT 221 D H R Q LL T G +T + LF + + F+ ++A++ Sbjct: 71 SDVH------RGFQHLLHTLNLPGHGLET----RVGSALFLSHNLKFLAKFLNDTMAVYE 120 Query: 222 PALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMRG 281 LF + D V + IN +K T K+ + + D ++ Y++F+ Sbjct: 121 AKLFHTNF---YDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEK 177 Query: 282 --FSQLPGVHEFWVDNSISVSVPMISGTGNFQHW--SDAQNNFSVTCVPLGERATLLLIQ 337 S +F+VD + +V VPM+ HW D SV + AT+ I Sbjct: 178 PFISSRTTPKDFYVDENTTVRVPMMLQDQE-HHWYLHDRYLPCSVLRMDYKGDATVFFIL 236 Query: 338 PHCTSDLDRVEALIFRNDLLTWIENPPPR----AIRLTLPQLEIRGSYNLQDLLAEDKLP 393 P+ + +E ++ L+ W R + L LP+ I GSY L +L Sbjct: 237 PN-QGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFT 295 Query: 394 TLLGAEANLSNIGDTNPRVGEVLNSILLELKAGEEEQPTTSVQQPGSPEALD-------- 445 L A+LS I T + E S KA + + + A+ Sbjct: 296 DLFSKWADLSGI--TKQQKLEASKSF---HKATLDVDEAGTEAAAATSFAIKFFSAQTNR 350 Query: 446 --VTLSSPFLFAIYEQDSGTLHFLGRVNNP 473 + + PFL I+ + ++ FLG+V +P Sbjct: 351 HILRFNRPFLVVIFSTSTQSVLFLGKVVDP 380 >6CJ7-A nrPDB Length = 390 Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 51/251 (20%), Positives = 115/251 (45%), Gaps = 13/251 (5%) Query: 235 PVLATEKINRFIKAVTGWKMN--LPLEGVSTDSTLLFNTYVHFQG--TMRGFSQLPGVHE 290 P LA + IN +I + T K++ + + +S ++ ++ V+F+G + Q Sbjct: 131 PALAAQNINSWIASKTNDKIDKLVSPDDLSGNTQMVMVNAVYFKGLWEIPFREQATQKRN 190 Query: 291 FWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLG-ERATLLLIQPHCTSDLDRVEA 349 F ++ + F+ + V +P +L+++ P +S++D + + Sbjct: 191 FTLNGGEKKVASFMQTRRYFKAGTHKPAMAKVVVLPFEYNEYSLIVVLPLKSSNVDALLS 250 Query: 350 LIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNI---G 406 + D+ ++++ PP+ + L LP+ I+ NL+ +L + + ++ +A L N+ G Sbjct: 251 SLSMEDVASFLD-LPPKDVALELPKFSIKADINLEPVLNKMGVSSIFTQQAELYNLGSHG 309 Query: 407 DTNPRVGEVLNSILLEL--KAGEEEQPTTSVQQPGSPE--ALDVTLSSPFLFAIYEQDSG 462 +P+V L+S +L + + G T+ S + +L + PFL +++ S Sbjct: 310 SLSPQVSSALHSAVLTIDERGGSAAAATSFAAVALSYDEPSLYFRANKPFLAILWDNRSS 369 Query: 463 TLHFLGRVNNP 473 F+ R+ +P Sbjct: 370 IPLFMARIMDP 380 >4DY0-A nrPDB Length = 379 Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 58/256 (22%), Positives = 109/256 (42%), Gaps = 18/256 (7%) Query: 234 DPVLATEKINRFIKAVTGWKMNLPL-----EGVSTDSTLLFNTYVHFQGTMRGFSQLPGV 288 DP A + IN ++K T ++ L +GV T L+ V+F+G + Q Sbjct: 126 DPASACDSINAWVKNETRDMIDNLLSPDLIDGVLT--RLVLVNAVYFKGLWKSRFQPENT 183 Query: 289 HE--FWVDNSISVSVPMISGTGNFQHWS-DAQNNFSVTCVPL---GERATLLLIQP-HCT 341 + F + S VPM++ F+ S A N+ + L GE ++L+ P + Sbjct: 184 KKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESS 243 Query: 342 SDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLL-GAEA 400 + L + I + +W+ P+ +++ LP+ +L++ L + + ++A Sbjct: 244 TPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKA 303 Query: 401 NLSNI--GDTNPRVGEVLNSILLEL-KAGEEEQPTTSVQQPGSPEALDVTLSSPFLFAIY 457 N + I G N V +L +E+ + G + T+ + PFLF I Sbjct: 304 NFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFLFFIR 363 Query: 458 EQDSGTLHFLGRVNNP 473 +G + F+G++N P Sbjct: 364 HNPTGAVLFMGQINKP 379 >4P0F-A nrPDB Length = 393 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 49/195 (25%), Positives = 90/195 (46%), Gaps = 24/195 (12%) Query: 123 ILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLV 182 + SP ++ LG+ + TA+QL L + + + + H+VLAA + Q L + Sbjct: 35 VFSPFSIQTCAAMARLGAENETATQLDQGLGLASSDPEQIAH-SFHQVLAAYQDSQILRI 93 Query: 183 TQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLAL-FTPALFPRSLDLSTDPVLATEK 241 +F G++L+ F Q L+ F A +S+D S + V A Sbjct: 94 ANK---------------IFVMDGYQLRQEFDQLLSKQFLSA--AQSVDFSKN-VQAAAT 135 Query: 242 INRFIKAVTGWKMN--LPLEGVSTDSTLLFNTYVHFQGT-MRGFSQ-LPGVHEFWVDNSI 297 IN +++ T + +P + ++++S L+ +HF+GT F++ L F +D Sbjct: 136 INNWVEQRTNHLIKDLVPADVLNSESRLVLVNAIHFKGTWQHQFAKHLTRPDTFHLDGER 195 Query: 298 SVSVPMISGTGNFQH 312 +V VPM+S F++ Sbjct: 196 TVQVPMMSLKERFRY 210 >4GA7-A nrPDB Length = 389 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 59/263 (22%), Positives = 112/263 (42%), Gaps = 18/263 (6%) Query: 228 SLDLSTDPVLATEKINRFIKAVTGWKM-NLPLEGVSTDST-LLFNTYVHFQGTMRG--FS 283 S+D A + IN+++K T K+ L G+ + T L+ ++F+G + Sbjct: 128 SVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMK 187 Query: 284 QLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPL-GERATLLLIQPHCTS 342 + F ++ +V M+ F + V +P GE +++++ P Sbjct: 188 EATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIE 247 Query: 343 D----LDRVEALIFRNDLLTWI--ENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLL 396 D L ++E + L W EN + ++LP+ ++ SY L LA + L Sbjct: 248 DESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLF 307 Query: 397 GA-EANLSNI-GDTNPRVGEVLNSILLELKAGEEEQPTTSVQQP----GSPEALDVTLSS 450 + +A+LS + G + + ++++ +E+ E + PE + T Sbjct: 308 NSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMDDPEE-NFTADH 366 Query: 451 PFLFAIYEQDSGTLHFLGRVNNP 473 PFLF I SG++ FLGR ++P Sbjct: 367 PFLFFIRHNSSGSILFLGRFSSP 389 >5NCS-A nrPDB Length = 375 Score = 38.9 bits (89), Expect = 0.006, Method: Compositional matrix adjust. Identities = 27/117 (23%), Positives = 56/117 (47%), Gaps = 6/117 (5%) Query: 360 IENPPPRAIRLTLPQLEIRGSYNLQD-LLAEDKLPTLLGAEANLSNIGDTNPRVGEVLNS 418 I+ P + L +P+ + Y L+ +L E + A+ I D + V++ Sbjct: 254 IKGIRPTQVSLRMPRFKTECKYGLEKKILPEMGMNVPFTETADFPGITDAAIFISRVIHK 313 Query: 419 ILLEL-KAGEEEQPTTSVQ--QPGSPEA--LDVTLSSPFLFAIYEQDSGTLHFLGRV 470 +++ + G E T+V+ + SP ++ ++ PF+FAI E+ +G + F+G + Sbjct: 314 TFVQVDEEGTEAAAVTAVEMVKTSSPSTTPINFHINKPFVFAIREKSTGVILFIGEI 370 >1C5G-A nrPDB Length = 402 Score = 37.7 bits (86), Expect = 0.012, Method: Compositional matrix adjust. Identities = 80/390 (20%), Positives = 161/390 (41%), Gaps = 31/390 (7%) Query: 97 VAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPV 156 VA +A+ G R+++ + +A S + SP + L L + T Q+Q + Sbjct: 31 VAHLASDFGVRVFQQVAQA-SKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGF-- 87 Query: 157 KEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFV-Q 215 ++D + ALR + L+ G ++ + S +F +L F+ Sbjct: 88 -------KIDDKGMAPALRHLYKELM---GPWNKDEI--STTDAIFVQRDLKLVQGFMPH 135 Query: 216 SLALFTPALFPRSLDLSTDPVLATEKINRFIKAVT-GWKMNLPLEG-VSTDSTLLFNTYV 273 LF + + +D S + A IN ++K T G NL +G V + L+ + Sbjct: 136 FFRLFRSTV--KQVDFS-EVERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNAL 192 Query: 274 HFQGTMRGFSQLPGVHE--FWVDNSISVSVPMISGTGNFQHW---SDAQNNFSVTCVPL- 327 +F G + H F + +VSVPM++ T F + + + + + +P Sbjct: 193 YFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYH 252 Query: 328 GERATLLLIQPHCTS-DLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDL 386 G+ ++ + P+ L + ++ + W N L LP+ + +L+ Sbjct: 253 GDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKP 312 Query: 387 LAEDKLPTLLGA-EANLSNIGDTNP-RVGEVLNSILLEL-KAGEEEQPTTSVQQPGSPEA 443 L + + +A+ +++ D P V + L + +E+ ++G +T+V Sbjct: 313 LENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAP 372 Query: 444 LDVTLSSPFLFAIYEQDSGTLHFLGRVNNP 473 ++ + PFLF + +GT+ F+G+V P Sbjct: 373 EEIIMDRPFLFVVRHNPTGTVLFMGQVMEP 402 >1HLE-A nrPDB Length = 345 Score = 35.8 bits (81), Expect = 0.042, Method: Compositional matrix adjust. Identities = 70/330 (21%), Positives = 141/330 (42%), Gaps = 32/330 (9%) Query: 108 MYKMLNEAGSGASGAI-LSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTSRLD 166 +++ LNE S +G I +SP ++ L +LG+ TA+Q+ L E D Sbjct: 16 LFRALNE--SDPTGNIFISPLSISSALAMIFLGTRGNTAAQVSKALYFDTVE-------D 66 Query: 167 GHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLALFTPALFP 226 H +L A + + G+ P + + L+ + F+ S A Sbjct: 67 IHSRFQSLNAD----INKPGA----PYILKLANRLYGEKTYNFLADFLASTQKMYGAELA 118 Query: 227 RSLDLSTDPVLATEKINRFIKAVTGWKM-NLPLEGVSTDST-LLFNTYVHFQGTMRGFSQ 284 S+D P A ++IN ++K T K+ L ++G+ + T L+ ++F+G + Sbjct: 119 -SVDFQQAPEDARKEINEWVKGQTEGKIPELLVKGMVDNMTKLVLVNAIYFKGNWQQKFM 177 Query: 285 LPGVHE--FWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPL-GERATLLLIQPHCT 341 + F ++ + +V M+ F + V +P G+ +++++ P Sbjct: 178 KEATRDAPFRLNKKDTKTVKMMYQKKKFPYNYIEDLKCRVLELPYQGKELSMIILLPDDI 237 Query: 342 SD----LDRVEALIFRNDLLTWI--ENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTL 395 D L+++E + + L W EN + + LP+ ++ SY+L LA + L Sbjct: 238 EDESTGLEKIEKQLTLDKLREWTKPENLYLAEVNVHLPRFKLEESYDLTSHLARLGVQDL 297 Query: 396 LG-AEANLSNI-GDTNPRVGEVLNSILLEL 423 +A+LS + G + V ++++ ++L Sbjct: 298 FNRGKADLSGMSGARDLFVSKIIHKSFVDL 327 >1SNG-A nrPDB Length = 370 Score = 32.3 bits (72), Expect = 0.48, Method: Compositional matrix adjust. Identities = 30/112 (26%), Positives = 48/112 (42%), Gaps = 4/112 (3%) Query: 367 AIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNIGDTNPRVGEVLNSILL---EL 423 ++ L LP+ E+ + L ++LAE + TL A A+LS I V V++ L E Sbjct: 253 SVELALPRFELTQPHQLVEVLAEAGVRTLFTASADLSGISTVPLYVDTVIHQARLRVDER 312 Query: 424 KAGEEEQPTTSVQQPGS-PEALDVTLSSPFLFAIYEQDSGTLHFLGRVNNPQ 474 A + G+ P + S F I + G + FLG + +P Sbjct: 313 GAEGAAATAAMMLLAGAMPPRRTIRFSVDRPFHIVVRRRGAILFLGSIADPH 364 >3LW2-A nrPDB Length = 379 Score = 31.6 bits (70), Expect = 0.87, Method: Compositional matrix adjust. Identities = 37/188 (19%), Positives = 82/188 (43%), Gaps = 16/188 (8%) Query: 298 SVSVPMISGTGNFQHWSDAQNN---FSVTCVPL-GERATLLLIQP-----HCTSDLDRVE 348 +VSVPM++ + F + + + V +P G+ ++ + P H ++ + ++ Sbjct: 196 TVSVPMMAQSNKFNYTEFTTPDGLEYDVVELPYQGDTLSMFIAAPFEKDVHLSALTNILD 255 Query: 349 ALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAE-ANLSNIGD 407 A + R W N L LP+ + +L+ L + +P + A A+ +++ D Sbjct: 256 AELIRQ----WKGNMTRLPRLLILPKFSLETEVDLRGPLEKLGMPDMFSATLADFTSLSD 311 Query: 408 TNP-RVGEVLNSILLEL-KAGEEEQPTTSVQQPGSPEALDVTLSSPFLFAIYEQDSGTLH 465 V + L + +E+ ++G +T+ ++ + FLF + + T+ Sbjct: 312 QEQLSVAQALQKVRIEVNESGTVASSSTAFVISARMAPTEMVIDRSFLFVVRHNPTETIL 371 Query: 466 FLGRVNNP 473 F+G+V P Sbjct: 372 FMGQVMEP 379 >2PEF-A nrPDB Length = 373 Score = 31.2 bits (69), Expect = 0.99, Method: Compositional matrix adjust. Identities = 61/293 (20%), Positives = 110/293 (37%), Gaps = 44/293 (15%) Query: 202 FTAPGFRLKHSFVQSLALFTPA-LFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEG 260 F F F+Q +A + A +F + D ST IN ++K+ T ++ L Sbjct: 97 FKENDFMPSKDFLQIIADYYKADIFKAAFDSST-----VSDINNWVKSKTNGMIDKILNK 151 Query: 261 VSTDSTLLFNTYVHFQGTMRGFSQLPGVHEFWVDNSISVSVPMISGTGNFQ--HWSDAQN 318 + + + V F + VHE I V GN Q + +++ Sbjct: 152 IDPEDVMYLINAVAFDAEWETVYEKASVHE-----DIFTDV-----YGNRQKVEFMNSEE 201 Query: 319 NFSVTCVPLGERATLLLIQPHCTSDLDRVEALIFRN-------------DLLTWIENPPP 365 N + E + ++P+ + V L N + I+N Sbjct: 202 NLYIE-----EENAVGFVKPYAKNHYSFVAILPDENISVNEYIKTLTGQKFIDLIKNAKI 256 Query: 366 RAIRLTLPQLEIRGSYNLQDLLAEDKL-PTLLGAEANLSNIGDT---NPRVGEVLNSILL 421 +R +LP+ + + + + L + L +A+ S +G + N + EVL+ + Sbjct: 257 TLVRASLPKFKYEYTIKMNETLESLGMTDAFLPDKADFSKLGKSDIGNLYISEVLHKTFI 316 Query: 422 EL-KAGEEEQPTTSVQ--QPGSPEALD-VTLSSPFLFAIYEQDSGTLHFLGRV 470 + + G + TSV G P V L+ PF+FAI + + F+G V Sbjct: 317 SVDELGTKAGAVTSVDITAAGIPVNFKTVKLNRPFIFAIIDNSTNLPIFIGTV 369 >3LE2-A nrPDB Length = 393 Score = 30.4 bits (67), Expect = 1.7, Method: Compositional matrix adjust. Identities = 81/400 (20%), Positives = 158/400 (39%), Gaps = 45/400 (11%) Query: 100 IANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEG 159 + N V + K + S S I SP ++ L GS T Q+ + L Sbjct: 11 LQNQVSMNLAKHVITTVSQNSNVIFSPASINVVLSIIAAGSAGATKDQILSFLKFS---- 66 Query: 160 DCTSRLDG--HKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSL 217 T +L+ ++++A+ A GS++ P L S+ G + K SF Q L Sbjct: 67 -STDQLNSFSSEIVSAVLA--------DGSANGGPKL-SVANGAWIDKSLSFKPSFKQLL 116 Query: 218 ALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDS--TLLFNTYVHF 275 A ++ D + V ++N + + T + L S DS L+F ++F Sbjct: 117 EDSYKAASNQA-DFQSKAVEVIAEVNSWAEKETNGLITEVLPEGSADSMTKLIFANALYF 175 Query: 276 QGTM-RGFSQ-LPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPL-----G 328 +GT F + L EF + + V+ P + T + + A + F V +P Sbjct: 176 KGTWNEKFDESLTQEGEFHLLDGNKVTAPFM--TSKKKQYVSAYDGFKVLGLPYLQGQDK 233 Query: 329 ERATLLLIQPHCTSDL-DRVEALIFRNDLLTWIENPPPRAIRL---TLPQLEIRGSYNLQ 384 + ++ P + L D ++ ++ L + P R +++ +P+ + ++ Sbjct: 234 RQFSMYFYLPDANNGLSDLLDKIVSTPGFLD--NHIPRRQVKVREFKIPKFKFSFGFDAS 291 Query: 385 DLLAEDKLPTLLGAEANLSNIGDT-----NPRVGEVLNSILLELKAGEEEQPTTS---VQ 436 ++L L + E L+ + ++ N V + + +E+ E S ++ Sbjct: 292 NVLKGLGLTSPFSGEEGLTEMVESPEMGKNLCVSNIFHKACIEVNEEGTEAAAASAGVIK 351 Query: 437 QPG---SPEALDVTLSSPFLFAIYEQDSGTLHFLGRVNNP 473 G + +D PFL + E +G + F+G+V +P Sbjct: 352 LRGLLMEEDEIDFVADHPFLLVVTENITGVVLFIGQVVDP 391 >1MTP-A nrPDB Length = 323 Score = 30.4 bits (67), Expect = 2.0, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 30/57 (52%) Query: 367 AIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNIGDTNPRVGEVLNSILLEL 423 ++ L LP+ E+ + L ++LAE + TL A A+LS I V V++ L + Sbjct: 249 SVELALPRFELTQPHQLVEVLAEAGVRTLFTASADLSGISTVPLYVDTVIHQARLRV 305 >3ICO-A nrPDB Length = 268 Score = 30.0 bits (66), Expect = 2.2, Method: Compositional matrix adjust. Identities = 18/62 (29%), Positives = 29/62 (46%), Gaps = 4/62 (6%) Query: 315 DAQNNFSVTCVPLGERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQ 374 D NF V + +G + + PH + L+ ++ +D PPPR I LTLP Sbjct: 156 DPAPNFDVHLLGMGPEGHINSLFPHSPAVLESTRMVVAVDD----SPKPPPRRITLTLPA 211 Query: 375 LE 376 ++ Sbjct: 212 IQ 213 >3PZF-A nrPDB Length = 397 Score = 30.0 bits (66), Expect = 2.5, Method: Compositional matrix adjust. Identities = 35/159 (22%), Positives = 61/159 (38%), Gaps = 17/159 (10%) Query: 328 GERATLLLIQPH----CTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNL 383 G + + I P+ LDR+ + L EN + +TLP+ + S L Sbjct: 241 GNKLAMYFILPNPDNTVNQVLDRINSASLHQALWYMEEN----EVNVTLPKFKFDFSEQL 296 Query: 384 QDLLAEDKLPTLLGAEANLSNIGDTNPRVGEVLNSILLELKA------GEEEQPTTSVQ- 436 + L + + + A+L + EV S + + G E T +Q Sbjct: 297 NEPLQQVGIREIFSQNASLPLLARGRGARDEVRVSRIFQKAGITINELGSEAYAATEIQL 356 Query: 437 --QPGSPEALDVTLSSPFLFAIYEQDSGTLHFLGRVNNP 473 + G + PF+F I ++ GT+ F G++ NP Sbjct: 357 VNKFGGDGVQIFNANRPFIFFIEDETLGTMLFAGKIENP 395 >1V9D-A nrPDB Length = 340 Score = 28.1 bits (61), Expect = 8.2, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 6/64 (9%) Query: 346 RVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNI 405 R+ A++F+ +EN P + +T E+R S N LL +L L+G N N Sbjct: 96 RLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSENFSSLL---ELTLLVG---NYMNA 149 Query: 406 GDTN 409 G N Sbjct: 150 GSRN 153 >3OBV-E nrPDB Length = 457 Score = 28.1 bits (61), Expect = 9.2, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 6/64 (9%) Query: 346 RVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNI 405 R+ A++F+ +EN P + +T E+R S N LL +L L+G N N Sbjct: 167 RLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSENFSSLL---ELTLLVG---NYMNA 220 Query: 406 GDTN 409 G N Sbjct: 221 GSRN 224 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2WXX-A nrPDB 582 e-166 2WXZ-C nrPDB 566 e-162 5M3Y-A nrPDB 491 e-139 6EE5-A nrPDB 445 e-125 6HGE-B nrPDB 392 e-109 5INW-A nrPDB 387 e-108 2VDY-A nrPDB 382 e-106 3NE4-A nrPDB 367 e-102 2OL2-A nrPDB 360 1e-99 1ATT-A nrPDB 356 1e-98 4EB1-I nrPDB 354 7e-98 5HGC-A nrPDB 352 3e-97 4ZK0-A nrPDB 347 7e-96 1BY7-A nrPDB 347 8e-96 1YXA-A nrPDB 347 8e-96 6F02-A nrPDB 340 6e-94 1UHG-A nrPDB 339 2e-93 4Y40-A nrPDB 332 2e-91 2V95-A nrPDB 332 2e-91 4AJT-A nrPDB 328 3e-90 3DY0-A nrPDB 328 3e-90 1JMJ-A nrPDB 325 2e-89 3NDA-A nrPDB 323 7e-89 6F4U-A nrPDB 312 3e-85 1QMB-A nrPDB 308 4e-84 4AJU-A nrPDB 307 8e-84 2R9Y-A nrPDB 303 1e-82 2XN5-A nrPDB 298 3e-81 4KDS-A nrPDB 297 7e-81 4DY0-A nrPDB 290 1e-78 1IMV-A nrPDB 283 8e-77 4DTE-A nrPDB 282 2e-76 3F02-A nrPDB 276 1e-74 4P0F-A nrPDB 276 1e-74 2OAY-A nrPDB 261 4e-70 3ZHA-A nrPDB 261 5e-70 1C8O-A nrPDB 255 3e-68 6CJ7-A nrPDB 253 1e-67 1JJO-C nrPDB 238 4e-63 1M93-B nrPDB 219 3e-57 Sequences not found previously or not previously below threshold: 4GA7-A nrPDB 294 5e-80 2H4P-A nrPDB 269 2e-72 2H4Q-A nrPDB 269 2e-72 1HLE-A nrPDB 268 3e-72 1C5G-A nrPDB 267 7e-72 3LW2-A nrPDB 258 3e-69 5NCS-A nrPDB 232 3e-61 1XQJ-A nrPDB 223 1e-58 1SEK-A nrPDB 206 1e-53 1K9O-I nrPDB 205 3e-53 3LE2-A nrPDB 202 3e-52 3OZQ-A nrPDB 201 5e-52 3PZF-A nrPDB 199 2e-51 5NCU-A nrPDB 198 3e-51 3STO-A nrPDB 194 6e-50 2PEF-A nrPDB 192 2e-49 6BJ5-B nrPDB 156 3e-38 1SNG-A nrPDB 146 2e-35 1MTP-A nrPDB 123 1e-28 5C98-A nrPDB 101 6e-22 4R9I-A nrPDB 74 2e-13 2P6F-A nrPDB 34 0.16 4GWP-B nrPDB 32 0.66 6GCS-K nrPDB 30 1.7 4X04-A nrPDB 30 2.7 3RG1-A nrPDB 29 3.9 5LN3-Z nrPDB 29 3.9 6BWI-A nrPDB 29 5.5 4PSX-A nrPDB 28 7.6 >2WXX-A nrPDB Length = 453 Score = 582 bits (1499), Expect = e-166, Method: Composition-based stats. Identities = 448/453 (98%), Positives = 451/453 (99%) Query: 25 DRVYIHPFHLLYHNKSTCAQLENPSVETLPESTFEPVPIQAKTSPVNEKTLHDQLVLAAE 84 DRVYIHPFHLLYHNKSTCAQLENPSVETLPESTFEPVPIQAKTSPVNEKTLHDQLVLAAE Sbjct: 1 DRVYIHPFHLLYHNKSTCAQLENPSVETLPESTFEPVPIQAKTSPVNEKTLHDQLVLAAE 60 Query: 85 KLEDEDRKRAAQVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPT 144 KLEDEDRKRAAQVAMI NFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPT Sbjct: 61 KLEDEDRKRAAQVAMITNFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPT 120 Query: 145 ASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTA 204 ASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSI+VGLFTA Sbjct: 121 ASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIVVGLFTA 180 Query: 205 PGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTD 264 PGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTD Sbjct: 181 PGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTD 240 Query: 265 STLLFNTYVHFQGTMRGFSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTC 324 STLLFNTYVHFQGTMRGFSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTC Sbjct: 241 STLLFNTYVHFQGTMRGFSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTC 300 Query: 325 VPLGERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQ 384 VPLGERATLLLIQPHC SDLDRVEALIF+NDLLTWIENPPPRAIRLTLPQLEIRGSYNLQ Sbjct: 301 VPLGERATLLLIQPHCISDLDRVEALIFQNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQ 360 Query: 385 DLLAEDKLPTLLGAEANLSNIGDTNPRVGEVLNSILLELKAGEEEQPTTSVQQPGSPEAL 444 DLLAEDKLPTLLGAEANL+NIGDTNPRVGEVLNSILLELKAGEEEQPTTSVQQPGSPEAL Sbjct: 361 DLLAEDKLPTLLGAEANLNNIGDTNPRVGEVLNSILLELKAGEEEQPTTSVQQPGSPEAL 420 Query: 445 DVTLSSPFLFAIYEQDSGTLHFLGRVNNPQSVV 477 DVTLSSPFLFAIYEQDSGTLHFLGRVNNPQSVV Sbjct: 421 DVTLSSPFLFAIYEQDSGTLHFLGRVNNPQSVV 453 >2WXZ-C nrPDB Length = 453 Score = 566 bits (1458), Expect = e-162, Method: Composition-based stats. Identities = 390/453 (86%), Positives = 417/453 (92%) Query: 25 DRVYIHPFHLLYHNKSTCAQLENPSVETLPESTFEPVPIQAKTSPVNEKTLHDQLVLAAE 84 DRVYIHPFHLLY++KSTCAQLENPSVETLPE TFEPVPIQAKTSPV+EKTL D+LVLA E Sbjct: 1 DRVYIHPFHLLYYSKSTCAQLENPSVETLPEPTFEPVPIQAKTSPVDEKTLRDKLVLATE 60 Query: 85 KLEDEDRKRAAQVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPT 144 KLE EDR+RAAQVAMIANF+GFRMYKML+EA ASGA+LSPPALFGTLVSFYLGSLDPT Sbjct: 61 KLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPT 120 Query: 145 ASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTA 204 ASQLQ LL VPVKEGDCTSRLDGHKVL AL+AVQGLLVTQGGSSSQTPLLQS +VGLFTA Sbjct: 121 ASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTA 180 Query: 205 PGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTD 264 PG RLK FV+SL FTPA+FPRSLDLSTDPVLA +KINRF++AVTGWKMNLPLEGVSTD Sbjct: 181 PGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTD 240 Query: 265 STLLFNTYVHFQGTMRGFSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTC 324 STL FNTYVHFQG MRGFSQL G+HEFWVDNS SVSVPM+SGTGNFQHWSDAQNNFSVT Sbjct: 241 STLFFNTYVHFQGKMRGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTR 300 Query: 325 VPLGERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQ 384 VPLGE TLLLIQP C SDLDRVE L+F++D LTWI+NPPPRAIRLTLPQLEIRGSYNLQ Sbjct: 301 VPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQ 360 Query: 385 DLLAEDKLPTLLGAEANLSNIGDTNPRVGEVLNSILLELKAGEEEQPTTSVQQPGSPEAL 444 DLLA+ KL TLLGAEANL +GDTNPRVGEVLNSILLEL+AGEEEQPT S QQPGSPE L Sbjct: 361 DLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQPGSPEVL 420 Query: 445 DVTLSSPFLFAIYEQDSGTLHFLGRVNNPQSVV 477 DVTLSSPFLFAIYE+DSG LHFLGRV+NPQ+VV Sbjct: 421 DVTLSSPFLFAIYERDSGALHFLGRVDNPQNVV 453 >5M3Y-A nrPDB Length = 458 Score = 491 bits (1263), Expect = e-139, Method: Composition-based stats. Identities = 274/452 (60%), Positives = 327/452 (72%), Gaps = 3/452 (0%) Query: 25 DRVYIHPFHLLYHNKSTCAQLENPSVETLPESTFEPVPIQAKTSPVNEKTLHDQLVLAAE 84 DRVYIHPFHL+ HN+STC QL + + TF P PIQAKTSPV+EK L DQLVL A Sbjct: 1 DRVYIHPFHLVIHNESTCEQLAKANAGKPKDPTFIPAPIQAKTSPVDEKALQDQLVLVAA 60 Query: 85 KLEDEDRKRAAQVAMIANFVGFRMYKMLNEAGSGASGA-ILSPPALFGTLVSFYLGSLDP 143 KL+ ED+ RAA V M+ANF+GFR+Y M +E GA +LSP A+FGTL S YLG+LD Sbjct: 61 KLDTEDKLRAAMVGMLANFLGFRIYGMHSELWGVVHGATVLSPTAVFGTLASLYLGALDH 120 Query: 144 TASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFT 203 TA +LQ +L VP K+ CTSRLD HKVL+AL+AVQGLLV QG + SQ LL S +VG+FT Sbjct: 121 TADRLQAILGVPWKDKQCTSRLDAHKVLSALQAVQGLLVAQGRADSQAQLLLSTVVGVFT 180 Query: 204 APGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVST 263 APG LK FVQ LAL+TP + PRSLD T+ +A EKI+RF++AVTGWK L G S Sbjct: 181 APGLHLKQPFVQGLALYTPVVLPRSLDF-TELDVAAEKIDRFMQAVTGWKTGSSLMGASV 239 Query: 264 DSTLLFNTYVHFQGTMRGFSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVT 323 DSTL FNTYVHFQG M+GFS L EFWVD S SVSVPM+SG G FQHWSD Q+ FSVT Sbjct: 240 DSTLAFNTYVHFQGKMKGFSLLAEPQEFWVDQSTSVSVPMLSGMGTFQHWSDIQDQFSVT 299 Query: 324 CVPLGERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNL 383 VP E A+LLLIQPH SDLD+VE L F+ + L W++ PR I LT+PQL ++GSY+L Sbjct: 300 QVPFTESASLLLIQPHYASDLDKVEGLTFQQNSLNWMKKLSPRTIHLTMPQLVLQGSYDL 359 Query: 384 QDLLAEDKLPTLLGAEANLSNIGDTNPRVGEVLNSILLELKAGEEEQPTTSVQQPGSPEA 443 QDLLA+ +LP +L E NL + + RVGEVLNSI EL+A E E PT S QQ PE Sbjct: 360 QDLLAQAELPAILHTELNLQKLSNDRIRVGEVLNSIFFELEADERE-PTESTQQLNKPEV 418 Query: 444 LDVTLSSPFLFAIYEQDSGTLHFLGRVNNPQS 475 L+VTL+ PFLFA+Y+Q + LHFLGRV NP S Sbjct: 419 LEVTLNRPFLFAVYDQSATALHFLGRVANPLS 450 >6EE5-A nrPDB Length = 379 Score = 445 bits (1145), Expect = e-125, Method: Composition-based stats. Identities = 100/394 (25%), Positives = 175/394 (44%), Gaps = 26/394 (6%) Query: 84 EKLEDEDRKRAAQVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDP 143 E L + + ++A F +Y+ L ++ S SP ++ L LG+ Sbjct: 8 ENLYFQGAASSHKLAEANTDFAFSLYRELAKS-SPDKNIFFSPVSISSALAMLSLGAKGD 66 Query: 144 TASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFT 203 T +Q+ L S D H+ Q LL T L GLF Sbjct: 67 THTQILEGLGFN-------SEADIHQ------GFQHLLQTLNRPK---GLQLKTANGLFV 110 Query: 204 APGFRLKHSFV-QSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVS 262 +L SF+ S L+ F S+D DP A ++IN +++ T K+ L+ + Sbjct: 111 DKSLKLLDSFLEDSKKLYQAEAF--SVDF--DPEEAKKQINDWVEKQTNGKIKDLLKDLD 166 Query: 263 TDSTLLFNTYVHFQGTMRGFSQLPGVHE--FWVDNSISVSVPMISGTGNFQHWSDAQNNF 320 +D+ L+ ++F+G + E F VD +V VPM+S G F ++ D + + Sbjct: 167 SDTVLVLVNAIYFKGKWKKPFDPENTKEEDFHVDEKTTVKVPMMSQKGKFYYYHDDELSC 226 Query: 321 SVTCVPLGERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGS 380 V +P A++L+I P L +E + L W+++ R++ L LP+ +I G+ Sbjct: 227 KVLELPYKGNASMLIILPD-EGGLQHLEQSLTPETLSKWLKSLTRRSVELYLPKFKIEGT 285 Query: 381 YNLQDLLAEDKLPTLLGAEANLSNIGDTNPRVGEVLNSILLEL-KAGEEEQPTTSVQQPG 439 Y+L+++L+ + L A+LS I + V + ++ +LE+ + G E T ++ Sbjct: 286 YDLKEVLSNLGITDLFSPGADLSGITEEKLYVSKAVHKAVLEVNEEGTEAAAATFLEAIP 345 Query: 440 SPEALDVTLSSPFLFAIYEQDSGTLHFLGRVNNP 473 + PFLF I E +G++ F+G+V NP Sbjct: 346 MSIPPEFKADRPFLFLIRENKTGSILFMGKVVNP 379 >6HGE-B nrPDB Length = 409 Score = 392 bits (1007), Expect = e-109, Method: Composition-based stats. Identities = 98/409 (23%), Positives = 174/409 (42%), Gaps = 31/409 (7%) Query: 81 LAAEKLEDEDRKRAAQVAM---IANF-VGFRMYKMLNEAGSGASGAILSPPALFGTLVSF 136 L E L E++ R V AN F +YK L + I SP ++ L Sbjct: 15 LDEENLTQENQDRGTHVDRGLASANVDFAFSLYKQL-VLKAPDKNVIFSPLSISTALAFL 73 Query: 137 YLGSLDPTASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQS 196 LG+ + T +++ L + E TS + H+ + Q LL T SS + L S Sbjct: 74 SLGAHNTTLTEILKGLKFNLTE---TSEAEIHQ------SFQHLLRTLNQSSDELQL--S 122 Query: 197 IMVGLFTAPGFRLKHSFVQSLA-LFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMN 255 + +F L F + L+ F D A + IN ++K T K+ Sbjct: 123 MGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDF---QDSAAAKKLINDYVKNGTRGKIT 179 Query: 256 LPLEGVSTDSTLLFNTYVHFQGTMRGFSQLPGVHE--FWVDNSISVSVPMISGTG-NFQH 312 ++ + + + ++ Y+ F+ H+ F++ V VPM+S + Sbjct: 180 DLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMSLHHLTIPY 239 Query: 313 WSDAQNNFSVTCVPLGERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAI-RLT 371 + D + + +V + A+ L I P ++ VEA++ R L W ++ R I L Sbjct: 240 FRDEELSCTVVQLNYTGNASALFILPD-QDKMEEVEAMLSRETLNRWGDSLEFREIGELY 298 Query: 372 LPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNI-GDTNPRVGEVLNSILLEL-KAGEEE 429 LP+ I YNL D+L + + ++A+LS I G N V +V++ +L++ + G E Sbjct: 299 LPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGTEA 358 Query: 430 QPTTSVQQPGSPEALD----VTLSSPFLFAIYEQDSGTLHFLGRVNNPQ 474 T+V+ ++ V + PFL I + + ++ F+ +V NP+ Sbjct: 359 SAATAVKITLLSALVETRTIVRFNRPFLMIIVDHFTWSIFFMSKVTNPK 407 >5INW-A nrPDB Length = 421 Score = 387 bits (994), Expect = e-108, Method: Composition-based stats. Identities = 105/434 (24%), Positives = 182/434 (41%), Gaps = 30/434 (6%) Query: 24 GDRVYIHPFHLLYHNKSTCAQLENPSVETLPESTFEPVPIQAKTSPVNEKTLHDQLVLAA 83 G+R Y+ PFHL+ + S A E P E+ P P+ SP Sbjct: 1 GERPYMQPFHLIPPSLSVQAT-EQPLASN--EAWDYPEPLAPGQSPAASSEEGSSEEKGD 57 Query: 84 EKLEDEDRKRAA----------QVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTL 133 E+ D + ++A N +GFR+YK + A SP ++ L Sbjct: 58 EREPHGDEGKRGRKDKKKSKTQRIASAVNGLGFRLYKQVLGGAGPADNIFFSPLSIASAL 117 Query: 134 VSFYLGSLDPTASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPL 193 G+ T ++L T L L G K +++ L S+ L Sbjct: 118 GVVTAGANGSTRAELDTALGF-------KEFLHGKKKAKSMKYFARLNGALYKRSAGFEL 170 Query: 194 LQSIMVGLFTAPGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWK 253 + +F+ G L F +++A + RS+D D A E +N +I+ VT K Sbjct: 171 MGK--NVVFSKKGLWLYRQFTRTVAHLFKSNV-RSVDF-GDSKNAVELMNAYIEKVTSKK 226 Query: 254 MNLPLEGVSTDSTLLFNTYVHFQGTM--RGFSQLPGVHEFWVDNSISVSVPMISGTGNFQ 311 + V TD++L+ ++F+G+ + L FWV++S S+ VP + Sbjct: 227 FPDVISDVDTDTSLVIVNVIYFKGSWGNKFEPDLTKNVRFWVNSSYSMMVPTMHQRAKLS 286 Query: 312 HWSDAQNNFSVTCVPLGERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENP--PPRAIR 369 + D + +V +P A++L+I PH T DL +VE + + L W+ ++ Sbjct: 287 YTQDRKLRSTVVKLPYEGGASMLVIVPHRTEDLPKVEESVSQEQLEEWLSLLGPSNHYVQ 346 Query: 370 LTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNI-GDTNPRVGEVLNSILLEL-KAGE 427 L+LP+ +I SY+L+ L+ + ++ A+LS I G V ++ + +L + + G Sbjct: 347 LSLPKFKISVSYDLKAYLSAMGMSSMFSYGADLSRITGMQKLHVDKITHKSVLHVNEEGT 406 Query: 428 EEQPTTSVQQPGSP 441 E + T V +P Sbjct: 407 EAKAETVVGIMAAP 420 >2VDY-A nrPDB Length = 373 Score = 382 bits (980), Expect = e-106, Method: Composition-based stats. Identities = 88/382 (23%), Positives = 155/382 (40%), Gaps = 21/382 (5%) Query: 97 VAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPV 156 +A F +YK L A S +SP ++ L LG+ T +QL L + Sbjct: 7 LASANVDFAFSLYKHL-VALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNL 65 Query: 157 KEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQS 216 E T G + L L A S T L ++ LF L SF Sbjct: 66 TERSETEIHQGFQHLHQLFA-----------KSDTSLEMTMGNALFLDGSLELLESFSAD 114 Query: 217 LALFT-PALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHF 275 + + + + D A+ +IN ++K T K+ G+ + + L+ Y+ F Sbjct: 115 IKHYYESEVLAMNF---QDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFF 171 Query: 276 QGTMRGFSQL--PGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATL 333 +GT L F+VD + V VPM+ + + D++ + + T+ Sbjct: 172 KGTWTQPFDLASTREENFYVDETTVVKVPMMLQSSTISYLHDSELPCQLVQMNYVGNGTV 231 Query: 334 LLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLP 393 I P ++ V A + R+ + W + L +P++ I G Y+L D+L E + Sbjct: 232 FFILPDK-GKMNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIA 290 Query: 394 TLLGAEANLSNIG-DTNPRVGEVLNSILLEL-KAGEEEQPTTSVQQPGSPEALDVTLSSP 451 L +AN S I D + +V++ +L+L + G E ++ + + + + P Sbjct: 291 DLFTTQANFSRITQDAQLKSSKVVHKAVLQLNEEGTEAAGAMFLEAIPRSKPIILRFNQP 350 Query: 452 FLFAIYEQDSGTLHFLGRVNNP 473 F+ I++ + + FL RV NP Sbjct: 351 FIIMIFDHFTWSSLFLARVMNP 372 >3NE4-A nrPDB Length = 424 Score = 367 bits (942), Expect = e-102, Method: Composition-based stats. Identities = 86/409 (21%), Positives = 168/409 (41%), Gaps = 21/409 (5%) Query: 70 VNEKTLHDQLVLAAEKLEDEDRKRAAQVAMIANFVGFRMYKMLNEAGSGASGAILSPPAL 129 + E D D+D ++ F +Y+ L S ++ SP ++ Sbjct: 29 LAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAH-QSNSTNIFFSPVSI 87 Query: 130 FGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSS 189 LG+ T ++ L+ + E H+ Q LL T S Sbjct: 88 ATAFAMLSLGTKADTHDEILEGLNFNLTE---IPEAQIHE------GFQELLRTLNQPDS 138 Query: 190 QTPLLQSIMVGLFTAPGFRLKHSFVQSLA-LFTPALFPRSLDLSTDPVLATEKINRFIKA 248 Q L + GLF + G +L F++ + L+ F + D A ++IN +++ Sbjct: 139 QLQL--TTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNF---GDTEEAKKQINDYVEK 193 Query: 249 VTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMRGFSQL--PGVHEFWVDNSISVSVPMISG 306 T K+ ++ + D+ Y+ F+G ++ +F VD +V VPM+ Sbjct: 194 GTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKR 253 Query: 307 TGNFQHWSDAQNNFSVTCVPLGERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPR 366 G F + + V + AT + P L +E + + + ++EN R Sbjct: 254 LGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPD-EGKLQHLENELTHDIITKFLENEDRR 312 Query: 367 AIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNIGDTNP-RVGEVLNSILLEL-K 424 + L LP+L I G+Y+L+ +L + + + A+LS + + P ++ + ++ +L + + Sbjct: 313 SASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDE 372 Query: 425 AGEEEQPTTSVQQPGSPEALDVTLSSPFLFAIYEQDSGTLHFLGRVNNP 473 G E ++ +V + PF+F + EQ++ + F+G+V NP Sbjct: 373 KGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 421 >2OL2-A nrPDB Length = 395 Score = 360 bits (923), Expect = 1e-99, Method: Composition-based stats. Identities = 89/378 (23%), Positives = 159/378 (42%), Gaps = 27/378 (7%) Query: 104 VGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTS 163 F +Y+ L A + SP ++ +L LG+ T Q+ L + +++ S Sbjct: 37 FTFDLYRALASAA-PSQNIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKS---S 92 Query: 164 RLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLA-LFTP 222 + H R Q LL L S+ LFT L+ +FV ++ L+ Sbjct: 93 EKELH------RGFQQLLQELNQPRDGFQL--SLGNALFTDLVVDLQDTFVSAMKTLYLA 144 Query: 223 ALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMRGF 282 FP + D A ++IN ++ T K+ L+ + +++ ++ Y+ F+ Sbjct: 145 DTFPTNF---RDSAGAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETS 201 Query: 283 SQL--PGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATLLLIQPHC 340 +F+V + V VPM+S + + D + V VP AT L I P Sbjct: 202 FNHKGTQEQDFYVTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILP-S 260 Query: 341 TSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEA 400 + +VE + L W++ R + L LP+ I GSY L+ +L + + + A Sbjct: 261 EGKMQQVENGLSEKTLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHA 320 Query: 401 NLSNIGD-TNPRVGEVLNSILLELKA-GEEEQPTTSVQQPGSPEALD---VTLSSPFLFA 455 +LS I + +N +V E+++ ++E+ G T L+ + + PFL Sbjct: 321 DLSGISNHSNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMF 380 Query: 456 IYEQDSGTLHFLGRVNNP 473 I + + + FLG+VN P Sbjct: 381 IVDNN---ILFLGKVNRP 395 >1ATT-A nrPDB Length = 429 Score = 356 bits (914), Expect = 1e-98, Method: Composition-based stats. Identities = 89/434 (20%), Positives = 175/434 (40%), Gaps = 30/434 (6%) Query: 55 ESTFEPV-PIQAKTSPVNEKTLHDQLVLAAEKLEDEDRKRAAQVAMIANFVGFRMYKMLN 113 + PV P+ S + T + +K+ +R +++ + Y+ L Sbjct: 8 KPRDIPVNPMCIYRSSEKKATEGQG---SEQKIPGATNRRVWELSKANSHFATAFYQHLA 64 Query: 114 EAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTSRLDGHKVLAA 173 ++ + LSP ++ LG+ + T +QL + V + D S ++ Sbjct: 65 DSKNNNDNIFLSPLSISTAFAMTKLGACNNTLTQL-----MEVFKFDTISEKTSDQIHFF 119 Query: 174 LRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQ-SLALFTPALFPRSLDLS 232 + L + SS+ LF ++ S ++ L P LD Sbjct: 120 FAKLNCRLYRKANKSSELVS----ANRLFGDKSITFNETYQDISEVVYGAKLQP--LDFK 173 Query: 233 TDPVLATEKINRFIKAVTGWKMNL--PLEGVSTDSTLLFNTYVHFQGTMR-GFSQLPGVH 289 + + IN++I T ++ P + ++ + L+ ++F+G + FS Sbjct: 174 GNAEQSRLTINQWISNKTEGRITDVIPPQAINEFTVLVLVNTIYFKGLWKSKFSPENTRK 233 Query: 290 E-FWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPL-GERATLLLIQPHCTSDLDRV 347 E F+ + S SV M+ F++ A++ V +P G+ T++LI P L +V Sbjct: 234 ELFYKADGESCSVLMMYQESKFRYRRVAEST-QVLELPFKGDDITMVLILPKLEKTLAKV 292 Query: 348 EALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAE-ANLSNI- 405 E + + L W++ + + +P+ I S+++++ L + L L E + L I Sbjct: 293 EQELTPDMLQEWLDELTETLLVVHMPRFRIEDSFSVKEQLQDMGLEDLFSPEKSRLPGIV 352 Query: 406 --GDTNPRVGEVLNSILLEL-KAGEEEQPTTSVQQPGS---PEALDVTLSSPFLFAIYEQ 459 G ++ V + + LE+ + G E +T + G + + + PFL I E Sbjct: 353 AEGRSDLYVSDAFHKAFLEVNEEGSEAAASTVISIAGRSLNSDRVTFKANRPFLVLIREV 412 Query: 460 DSGTLHFLGRVNNP 473 T+ F+GRV NP Sbjct: 413 ALNTIIFMGRVANP 426 >4EB1-I nrPDB Length = 440 Score = 354 bits (907), Expect = 7e-98, Method: Composition-based stats. Identities = 91/442 (20%), Positives = 175/442 (39%), Gaps = 38/442 (8%) Query: 55 ESTFEPV-PIQAKTSPVNEKTLHDQLVLAAEKLEDEDRKRAAQVAMIANFVGFRMYKMLN 113 + P+ P+ SP + T + + +K+ + +R +++ + Y+ L Sbjct: 11 KPRDIPMNPMCIYRSPEKKATEDEG---SEQKIPEATNRRVWELSKANSRFATTFYQHLA 67 Query: 114 EAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTSRLDGHKVLAA 173 ++ + LSP ++ LG+ + T QL + V + D S ++ Sbjct: 68 DSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQL-----MEVFKFDTISEKTSDQIHFF 122 Query: 174 LRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQ-SLALFTPALFPRSLDLS 232 + L + +S+ LF ++ S ++ L P LD Sbjct: 123 FAKLNCRLYRKANKASKLVS----ANRLFGDKSLTFNETYQDISELVYGAKLQP--LDFK 176 Query: 233 TDPVLATEKINRFIKAVTGWKMNL--PLEGVS--------TDSTLLFNTYVHFQGTMR-G 281 + + IN+++ T ++ P E ++ T + L+ ++F+G + Sbjct: 177 ENAEQSRAAINKWVSNKTEGRITDVIPSEAINVLVLVNTRTSTVLVLVNTIYFKGLWKSK 236 Query: 282 FSQLPGVHE-FWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPL-GERATLLLIQPH 339 FS E F+ + S S M+ G F++ A+ V +P G+ T++LI P Sbjct: 237 FSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAEGT-QVLELPFKGDDITMVLILPK 295 Query: 340 CTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAE 399 L +VE + L W++ + + +P+ I ++L++ L + L L E Sbjct: 296 PEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPE 355 Query: 400 -ANLSNI---GDTNPRVGEVLNSILLEL-KAGEEEQPTTSVQQPGS---PEALDVTLSSP 451 + L I G + V + + LE+ + G E +T+V G P + + P Sbjct: 356 KSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRP 415 Query: 452 FLFAIYEQDSGTLHFLGRVNNP 473 FL I E T+ F+GRV NP Sbjct: 416 FLVFIREVPLNTIIFMGRVANP 437 >5HGC-A nrPDB Length = 380 Score = 352 bits (902), Expect = 3e-97, Method: Composition-based stats. Identities = 78/375 (20%), Positives = 157/375 (41%), Gaps = 21/375 (5%) Query: 104 VGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTS 163 F+ ++ + + SP ++ LG+ T SQ+ L + E Sbjct: 18 FAFQFFREVTQEA-PNKNIFYSPVSISTAFAMLALGARSATQSQILEGLAFNLTEIQEKE 76 Query: 164 RLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLA-LFTP 222 +G L+ L ++M +F L F+ L+ Sbjct: 77 IHEG---------FHNLIHMLNHPEGGVQL--NMMNAIFVTAALALLRKFLDDAKALYQL 125 Query: 223 ALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMRGF 282 F + P A ++IN +I+ T K+ ++ + + +L ++V+F+G+ Sbjct: 126 EAFTTDFN---KPTEAEKQINDYIERKTHGKITNLVKDMDPQTVMLLASFVYFKGSWEKP 182 Query: 283 SQ--LPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATLLLIQPHC 340 + EF+VD +V VPM+ G F + D + + +V + AT L+ P Sbjct: 183 FEAEHTEEREFFVDAETTVKVPMMYQMGRFDFYFDEELSCTVVRLHYNGSATAFLVLP-A 241 Query: 341 TSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEA 400 + ++E + + + W ++ R + L P+ I GSY + + L + + + +A Sbjct: 242 KGKMKQLEQTLDKETIQKWSDHLFQRFMNLYFPKFSISGSYEISNTLRKMGIVDVFTNQA 301 Query: 401 NLSNI-GDTNPRVGEVLNSILLEL-KAGEEEQPTTSVQQPGSPEALDVTLSSPFLFAIYE 458 +LS I G + +V +V++ L++ + G E T+V+ + S PFL I++ Sbjct: 302 DLSGITGSPDLKVSKVVHKASLDVDEKGTEAAAATAVEIMPISFPPTIEFSHPFLMLIFD 361 Query: 459 QDSGTLHFLGRVNNP 473 +D+ + F+G++ NP Sbjct: 362 RDTNSTLFIGKIVNP 376 >4ZK0-A nrPDB Length = 390 Score = 347 bits (890), Expect = 7e-96, Method: Composition-based stats. Identities = 74/385 (19%), Positives = 158/385 (41%), Gaps = 20/385 (5%) Query: 104 VGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTS 163 F +++ S + SP ++ L LG+ D TA Q++ +L + T Sbjct: 11 FMFDLFQQFR--KSKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQVTENTTG 68 Query: 164 RLDGHKVLAA---LRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLALF 220 + + V + Q LL S+ L I LF + ++ ++ F Sbjct: 69 KAATYHVDRSGNVHHQFQKLLTEFNKSTDAYEL--KIANKLFGEKTYLFLQEYLDAIKKF 126 Query: 221 TPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPL--EGVSTDSTLLFNTYVHFQGT 278 S+D + P + +KIN ++++ T K+ + + +++TL+ ++F+G Sbjct: 127 YQTSV-ESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYFKGQ 185 Query: 279 M--RGFSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGE-RATLLL 335 + + +FW + + S+ M+ +F S V +P ++++ Sbjct: 186 WEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGKDLSMIV 245 Query: 336 IQPHCTSDLDRVEALIFRNDLLTW--IENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLP 393 + P+ L ++E + L+ W ++N + L LP+ ++ SY+L+D L + Sbjct: 246 LLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLRTMGMV 305 Query: 394 TLLGAEANLSNI-GDTNPRVGEVLNSILLELKAGEEEQPTTSVQQP----GSPEALDVTL 448 + +A+LS + G + VL+ +E+ E + + + Sbjct: 306 DIFNGDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTSTNEEFHC 365 Query: 449 SSPFLFAIYEQDSGTLHFLGRVNNP 473 + PFLF I + + ++ F GR ++P Sbjct: 366 NHPFLFFIRQNKTNSILFYGRFSSP 390 >1BY7-A nrPDB Length = 382 Score = 347 bits (889), Expect = 8e-96, Method: Composition-based stats. Identities = 76/389 (19%), Positives = 154/389 (39%), Gaps = 28/389 (7%) Query: 100 IANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEG 159 ++K L +A S LSP ++ T+ Y+GS T Q+ +L Sbjct: 7 ANTLFALNLFKHLAKA-SPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVG- 64 Query: 160 DCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLAL 219 K+ ++ R++ + +S+ LL+S+ LF + +++ Sbjct: 65 -----AAADKIHSSFRSLSSAI----NASTGNYLLESV-NKLFGEKSASFREEYIRLCQK 114 Query: 220 FTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEG--VSTDSTLLFNTYVHFQG 277 + + P+++D A +KIN ++K T K+ L V D+ ++ V+F+G Sbjct: 115 YYSSE-PQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSVDGDTRMVLVNAVYFKG 173 Query: 278 TMRGFSQ--LPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATLLL 335 + + L G++ F V+++ V M+ + +P ++ L Sbjct: 174 KWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLKAQILELPYAGDVSMFL 233 Query: 336 IQPHCTSD----LDRVEALIFRNDLLTWI--ENPPPRAIRLTLPQLEIRGSYNLQDLLAE 389 + P +D L+ +E+ I + L W + + + +PQ ++ Y L+ +L Sbjct: 234 LLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEVYIPQFKLEEHYELRSILRS 293 Query: 390 DKLPTLLGAE-ANLSNIGDTN-PRVGEVLNSILLEL-KAGEEEQPTTSVQQPGSP--EAL 444 + AN S + + N + EV + ++++ + G E T G Sbjct: 294 MGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEGTEAAAGTGGVMTGRTGHGGP 353 Query: 445 DVTLSSPFLFAIYEQDSGTLHFLGRVNNP 473 PFLF I + + + F GR ++P Sbjct: 354 QFVADHPFLFLIMHKITNCILFFGRFSSP 382 >1YXA-A nrPDB Length = 398 Score = 347 bits (889), Expect = 8e-96, Method: Composition-based stats. Identities = 89/409 (21%), Positives = 160/409 (39%), Gaps = 31/409 (7%) Query: 81 LAAEKLEDEDRKRAAQV-----AMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVS 135 L + ED Q+ A I F +YK L + + + SP ++ L Sbjct: 6 LGMDAAVQEDHDNGTQLDSLTLASINTDFAFSLYKEL-VLKNPDTNIVFSPLSISAALAL 64 Query: 136 FYLGSLDPTASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQ 195 LG+ T ++ L + E TS D H+ LL Q + Sbjct: 65 VSLGAKGNTLEEILEGLKFNLTE---TSEADIHQ------GFGHLLQRLNQPKDQVQI-- 113 Query: 196 SIMVGLFTAPGFRLKHSFVQSLA-LFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKM 254 S LF ++ F + L+ F P A + IN +++ T + Sbjct: 114 STGSALFIEKRQQILTEFQEKAKTLYQAEAFTADF---QQPRQAKKLINDYVRKQTQGMI 170 Query: 255 NLPLEGVSTDSTLLFNTYVHFQGTMR-GFSQLPGVH-EFWVDNSISVSVPMISGTG-NFQ 311 + + + ++ Y++F+ + F L EF+ V VPM+S Sbjct: 171 KELVSDLDKRTLMVLVNYIYFKAKWKVPFDPLDTFKSEFYCGKRRPVIVPMMSMEDLTTP 230 Query: 312 HWSDAQNNFSVTCVPLGERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAI-RL 370 ++ D + + +V + A+ L I P + +VEA + L W + PR I L Sbjct: 231 YFRDEELSCTVVELKYTGNASALFILPD-QGRMQQVEASLQPETLRKWKNSLKPRMIDEL 289 Query: 371 TLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNI-GDTNPRVGEVLNSILLELKAGEEE 429 LP+ I Y+L+D+L++ + + +A+LS I G + RV +V++ +L++ E Sbjct: 290 HLPKFSISTDYSLEDVLSKLGIREVFSTQADLSAITGTKDLRVSQVVHKAVLDVAETGTE 349 Query: 430 QPTT----SVQQPGSPEALDVTLSSPFLFAIYEQDSGTLHFLGRVNNPQ 474 V L V + PFL I++ ++ F+ ++ NP+ Sbjct: 350 AAAATGVKFVPMSAKLYPLTVYFNRPFLIMIFDTETEIAPFIAKIANPK 398 >6F02-A nrPDB Length = 389 Score = 340 bits (873), Expect = 6e-94, Method: Composition-based stats. Identities = 82/391 (20%), Positives = 141/391 (36%), Gaps = 29/391 (7%) Query: 96 QVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVP 155 ++A FR Y ++ G SP ++ LG+ + SQ+ L Sbjct: 6 KIAPANADFAFRFYYLIASETPG-KNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFN 64 Query: 156 VKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQ 215 + E S D H R Q LL T L + LF + + F+ Sbjct: 65 LTE---LSESDVH------RGFQHLLHTLN--LPGHGLETRVGSALFLSHNLKFLAKFLN 113 Query: 216 S-LALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVH 274 +A++ LF + D V + IN +K T K+ + + D ++ Y++ Sbjct: 114 DTMAVYEAKLFHTNF---YDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIY 170 Query: 275 FQGTMRGFS--QLPGVHEFWVDNSISVSVPMISGTGNFQ-HWSDAQNNFSVTCVPLGERA 331 F+ +F+VD + +V VPM+ + D SV + A Sbjct: 171 FKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDA 230 Query: 332 TLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPR----AIRLTLPQLEIRGSYNLQDLL 387 T+ I P+ + +E ++ L+ W R + L LP+ I GSY L +L Sbjct: 231 TVFFILPN-QGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQIL 289 Query: 388 AEDKLPTLLGAEANLSNIGDTN-PRVGEVLNSILLELKAGEEEQPTTSVQQPGSPEALD- 445 L A+LS I + + L++ E + A Sbjct: 290 PRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTN 349 Query: 446 ---VTLSSPFLFAIYEQDSGTLHFLGRVNNP 473 + + PFL I+ + ++ FLG+V +P Sbjct: 350 RHILRFNRPFLVVIFSTSTQSVLFLGKVVDP 380 >1UHG-A nrPDB Length = 385 Score = 339 bits (869), Expect = 2e-93, Method: Composition-based stats. Identities = 78/396 (19%), Positives = 159/396 (40%), Gaps = 28/396 (7%) Query: 95 AQVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDV 154 + + F ++K L + P A+ L YLG+ D T +Q+ ++ Sbjct: 1 GSIGAASMEFCFDVFKELKVHHANE-NIFYCPIAIMSALAMVYLGAKDSTRTQINKVVRF 59 Query: 155 P-------VKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGF 207 E C + ++ H ++LR + + S S+ L+ + Sbjct: 60 DKLPGFGDSIEAQCGTSVNVH---SSLRDILNQITKPNDVYSF-----SLASRLYAEERY 111 Query: 208 RLKHSFVQSLA-LFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEG--VSTD 264 + ++Q + L+ L P + + D A E IN ++++ T + L+ V + Sbjct: 112 PILPEYLQCVKELYRGGLEPINFQTAAD--QARELINSWVESQTNGIIRNVLQPSSVDSQ 169 Query: 265 STLLFNTYVHFQGTMRGFS--QLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSV 322 + ++ + F+G + F V S V M+ G F+ S A + Sbjct: 170 TAMVLVNAIVFKGLWEKAFKDEDTQAMPFRVTEQESKPVQMMYQIGLFRVASMASEKMKI 229 Query: 323 TCVPLG-ERATLLLIQPHCTSDLDRVEALIFRNDLLTWIEN--PPPRAIRLTLPQLEIRG 379 +P ++L++ P S L+++E++I L W + R I++ LP++++ Sbjct: 230 LELPFASGTMSMLVLLPDEVSGLEQLESIINFEKLTEWTSSNVMEERKIKVYLPRMKMEE 289 Query: 380 SYNLQDLLAEDKLPTLLGAEANLSNIGD-TNPRVGEVLNSILLEL-KAGEEEQPTTSVQQ 437 YNL +L + + + ANLS I + ++ + +++ E+ +AG E + Sbjct: 290 KYNLTSVLMAMGITDVFSSSANLSGISSAESLKISQAVHAAHAEINEAGREVVGSAEAGV 349 Query: 438 PGSPEALDVTLSSPFLFAIYEQDSGTLHFLGRVNNP 473 + + + PFLF I + + F GR +P Sbjct: 350 DAASVSEEFRADHPFLFCIKHIATNAVLFFGRCVSP 385 >4Y40-A nrPDB Length = 414 Score = 332 bits (852), Expect = 2e-91, Method: Composition-based stats. Identities = 86/415 (20%), Positives = 168/415 (40%), Gaps = 28/415 (6%) Query: 63 IQAKTSPVNEKTLHDQLVLAAEKLEDEDRKRAAQVAMIANFVGFRMYKMLNEAGSGASGA 122 ++ SP N K L +E + R A ++A +GF++ K L + Sbjct: 21 MKPSFSPRNYKAL-------SEVQGWKQRMAAKELARQNMDLGFKLLKKLA-FYNPGRNI 72 Query: 123 ILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLV 182 LSP ++ LG+ D T +++ + H ++ L Sbjct: 73 FLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFRKMPEKDLHE-GFHYIIHEL-------- 123 Query: 183 TQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKI 242 + L SI LF + + F++ F A L + +A ++I Sbjct: 124 ----TQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAE--TILTNFQNLEMAQKQI 177 Query: 243 NRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMRGFSQL--PGVHEFWVDNSISVS 300 N FI T K+N +E + + +L Y+ F+ + +F+++ + SV Sbjct: 178 NDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLEKNSSVK 237 Query: 301 VPMISGTGNFQHWSDAQNNFSVTCVPLGERATLLLIQPHCTSDLDRVEALIFRNDLLTWI 360 VPM+ +G +Q D + + ++ +P + T + I P L +E + + W Sbjct: 238 VPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPD-EGKLKHLEKGLQVDTFSRWK 296 Query: 361 ENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNIG-DTNPRVGEVLNSI 419 R + +++P+L + G+++L+ L+ + + +L+ I + +VGE ++ Sbjct: 297 TLLSRRVVCVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGEAVHKA 356 Query: 420 LLELKA-GEEEQPTTSVQQPGSPEALDVTLSSPFLFAIYEQDSGTLHFLGRVNNP 473 L++ G E T Q L V + P+L IY + ++ FLG++ NP Sbjct: 357 ELKMDERGTEGAAGTGAQTLPMETPLCVKIDKPYLLLIYSEKIPSVLFLGKIVNP 411 >2V95-A nrPDB Length = 371 Score = 332 bits (851), Expect = 2e-91, Method: Composition-based stats. Identities = 74/373 (19%), Positives = 157/373 (42%), Gaps = 21/373 (5%) Query: 104 VGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTS 163 F +Y+ L A + ++SP ++ L LG +Q L + E TS Sbjct: 16 FAFNLYQRL-VALNPDKNTLISPVSISMALAMVSLG---SAQTQSLQSLGFNLTE---TS 68 Query: 164 RLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLALFTPA 223 + H+ L + S T L ++ +F +LK SF+ + + + Sbjct: 69 EAEIHQSFQYLNYLLKQ--------SDTGLEMNMGNAMFLLQKLKLKDSFLADVKQYYES 120 Query: 224 LFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMRGFS 283 ++D D A+++IN+ +K T K+ + + ++ + Y+ +G Sbjct: 121 E-ALAIDF-EDWTKASQQINQHVKDKTQGKIEHVFSDLDSPASFILVNYIFLRGIWELPF 178 Query: 284 QL--PGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATLLLIQPHCT 341 +F+V+ + +V VPM+ +G+ ++ D+ + + T I P Sbjct: 179 SPENTREEDFYVNETSTVKVPMMVQSGSIGYFRDSVFPCQLIQMDYVGNGTAFFILPD-Q 237 Query: 342 SDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEAN 401 +D V A + R+ + W + PR + L +P+ + +Y+L+D+L + + LL +++ Sbjct: 238 GQMDTVIAALSRDTIDRWGKLMTPRQVNLYIPKFSMSDTYDLKDVLEDLNIKDLLTNQSD 297 Query: 402 LSNIGDTNPRVGEVLNSILLELKAGEEEQPTT-SVQQPGSPEALDVTLSSPFLFAIYEQD 460 S P +++ +L+L G +T E LD+ + PF+ ++++ Sbjct: 298 FSGNTKDVPLTLTMVHKAMLQLDEGNVLPNSTNGAPLHLRSEPLDIKFNKPFILLLFDKF 357 Query: 461 SGTLHFLGRVNNP 473 + + + +V NP Sbjct: 358 TWSSLMMSQVVNP 370 >4AJT-A nrPDB Length = 427 Score = 328 bits (841), Expect = 3e-90, Method: Composition-based stats. Identities = 88/383 (22%), Positives = 157/383 (40%), Gaps = 20/383 (5%) Query: 96 QVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVP 155 Q++ + GF + + ++ G I SP L +V+ LG+ T Q++ L++ Sbjct: 57 QLSNETSSFGFNLLRKISMRHDG--NVIFSPFGLSVAMVNLMLGTKGETKVQIENGLNL- 113 Query: 156 VKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQ 215 S+ + A + V+ SS L S F F +K ++ Sbjct: 114 ----QALSQAGPLILPALFKKVK------ETFSSNRDLGLSQGSFAFIHKDFDIKETYFN 163 Query: 216 SLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHF 275 + + S++ + A IN I T K+ + ++ ++ L+ YV F Sbjct: 164 LSKKYFDIEY-VSINF-QNSSQARGLINHCIVKETEGKIPKLFDEINPETKLILVDYVLF 221 Query: 276 QGTMRGFSQL--PGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATL 333 +G F +D ++ VPM+ GNF D + + +P AT+ Sbjct: 222 KGKWLTPFDPSFTEADTFHLDKYRAIKVPMMYREGNFTSTFDKKFRCHILKLPYQGNATM 281 Query: 334 LLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLP 393 L++ T D +E + + + TW++N R + + P+ ++ Y + +LL + + Sbjct: 282 LVVLMEKTGDYLALEDYLTVDLVETWLQNMKTRKMEVFFPKFKLNQRYEMHELLKQMGIR 341 Query: 394 TLLGAEANLSNIG--DTNPRVGEVLNSILLELKA-GEEEQPTTSVQQPGSPEALDVTLSS 450 L A+LS + N +V VL +LE+ G E T + + ++ Sbjct: 342 RLFSTSADLSELSAMARNLQVSRVLQQSVLEVDERGTEAVSGTLSEIIAYSMPPAIKVNR 401 Query: 451 PFLFAIYEQDSGTLHFLGRVNNP 473 PF F IYE+ S L FLGRV NP Sbjct: 402 PFHFIIYEEMSRMLLFLGRVVNP 424 >3DY0-A nrPDB Length = 336 Score = 328 bits (841), Expect = 3e-90, Method: Composition-based stats. Identities = 78/337 (23%), Positives = 141/337 (41%), Gaps = 21/337 (6%) Query: 104 VGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTS 163 F +Y+ L A + SP ++ +L LG+ T Q+ L + +++ S Sbjct: 12 FTFDLYRALASAA-PSQNIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKS---S 67 Query: 164 RLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLA-LFTP 222 + H R Q LL L S+ LFT L+ +FV ++ L+ Sbjct: 68 EKELH------RGFQQLLQELNQPRDGFQL--SLGNALFTDLVVDLQDTFVSAMKTLYLA 119 Query: 223 ALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMRGF 282 FP + D A ++IN ++ T K+ L+ + +++ ++ Y+ F+ Sbjct: 120 DTFPTNF---RDSAGAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETS 176 Query: 283 SQL--PGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATLLLIQPHC 340 +F+V + V VPM+S + + D + V VP AT L I P Sbjct: 177 FNHKGTQEQDFYVTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILP-S 235 Query: 341 TSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEA 400 + +VE + L W++ R + L LP+ I GSY L+ +L + + + A Sbjct: 236 EGKMQQVENGLSEKTLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHA 295 Query: 401 NLSNIGD-TNPRVGEVLNSILLELKA-GEEEQPTTSV 435 +LS I + +N +V E+++ ++E+ G T Sbjct: 296 DLSGISNHSNIQVSEMVHKAVVEVDESGTRAAAATGT 332 >1JMJ-A nrPDB Length = 480 Score = 325 bits (834), Expect = 2e-89, Method: Composition-based stats. Identities = 72/386 (18%), Positives = 153/386 (39%), Gaps = 12/386 (3%) Query: 91 RKRAAQVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQT 150 + R ++ ++ F +Y++L + + ++P + + LG T Q+ + Sbjct: 101 KSRIQRLNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHS 160 Query: 151 LLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLK 210 +L D + +++ + L + L+ F + Sbjct: 161 ILHF----KDFVNASSKYEITTIHNLFRKLTHRL--FRRNFGYTLRSVNDLYIQKQFPIL 214 Query: 211 HSFVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFN 270 F + + A + D S DP ++ N I +T + LE + + ++ Sbjct: 215 LDFKTKVREYYFAEAQIA-DFS-DPAFISKT-NNHIMKLTKGLIKDALENIDPATQMMIL 271 Query: 271 TYVHFQGTM--RGFSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLG 328 ++F+G+ + ++ H F ++ V V M+ GNF +D + + + + Sbjct: 272 NCIYFKGSWVNKFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYV 331 Query: 329 ERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLA 388 ++L++ PH S + +EA + + W ++ R + LP+ ++ +YNL + L Sbjct: 332 GGISMLIVVPHKMSGMKTLEAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLK 391 Query: 389 EDKLPTLLGAEANLSNIGDTNPRVGEVLNSILLEL-KAGEEEQPTTSVQQPGSPEALDVT 447 + L N++ I D + + + + + G + T+V + T Sbjct: 392 LMGIRMLFDKNGNMAGISDQRIAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFT 451 Query: 448 LSSPFLFAIYEQDSGTLHFLGRVNNP 473 + PFLF IYE + L F+GRV NP Sbjct: 452 VDRPFLFLIYEHRTSCLLFMGRVANP 477 >3NDA-A nrPDB Length = 377 Score = 323 bits (829), Expect = 7e-89, Method: Composition-based stats. Identities = 69/386 (17%), Positives = 146/386 (37%), Gaps = 22/386 (5%) Query: 95 AQVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDV 154 A++ N G R+ + L SP ++ + + G+ T +L L Sbjct: 5 AKLTKANNRFGLRLLRALPS--GPEKNVFFSPYSVSTAMGMAFAGARGQTQQELSQGLGF 62 Query: 155 PVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFV 214 + LD + T+ S+ + + L +S+ Sbjct: 63 SDVDLTDAGVLDAYTHH-----------TERLKSTPSNSTLDVANAAAIQRTLALLNSYE 111 Query: 215 QSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPL-EGVSTDSTLLFNTYV 273 +L A +D + +P A + +N ++K T K+ E + D+ L+ + Sbjct: 112 SALQSSFGAEL-HKVDFAGEPQAAVDFVNNWVKRKTHDKIEKLFNEPLDPDTLLVLLNAI 170 Query: 274 HFQGTMRG-FSQLPGVHEFWVDNSIS-VSVPMISGTGNFQHWSDAQNNFSVTCVPLGE-R 330 +F+G F + + + ++ V V + ++ V +P Sbjct: 171 YFKGEWNTAFVKEHTEKRQFFNGGVTPVEVDTMRLEARIKYRFFDDLQVEVVELPYRGLD 230 Query: 331 ATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAED 390 T+ ++ P + ++ ++ + + ++ + R I + LP+ ++ Y+L+ L Sbjct: 231 YTMAILLPKENTGVEGLKQNLTIDRFQNYLSDLRERKITVLLPKFKLETKYSLKAPLQSL 290 Query: 391 KLPTLLGAEANLSNIGDTNPRVGEVLNSILLEL-KAGEEEQPTTSVQQPG---SPEALDV 446 + + + A+LS I D + RV V + ++E+ + G TT V PE + Sbjct: 291 GIKQIFESGADLSGINDGSLRVSAVEHKAVVEVNEEGTVAAATTGVVIVPYSLGPEPVVF 350 Query: 447 TLSSPFLFAIYEQDSGTLHFLGRVNN 472 + PFLF I + + F+G+VN Sbjct: 351 RVDHPFLFFIRNTRTDDIFFVGQVNK 376 >6F4U-A nrPDB Length = 341 Score = 312 bits (798), Expect = 3e-85, Method: Composition-based stats. Identities = 71/338 (21%), Positives = 121/338 (35%), Gaps = 25/338 (7%) Query: 96 QVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVP 155 ++A FR Y ++ G SP ++ LG+ + SQ+ L Sbjct: 4 KIAPANADFAFRFYYLIASETPG-KNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFN 62 Query: 156 VKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQ 215 + E S D H R Q LL T L + LF + + F+ Sbjct: 63 LTE---LSESDVH------RGFQHLLHTLN--LPGHGLETRVGSALFLSHNLKFLAKFLN 111 Query: 216 S-LALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVH 274 +A++ LF + D V + IN +K T K+ + + D ++ Y++ Sbjct: 112 DTMAVYEAKLFHTNF---YDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIY 168 Query: 275 FQGTMRGFS--QLPGVHEFWVDNSISVSVPMISGTGNFQ-HWSDAQNNFSVTCVPLGERA 331 F+ +F+VD + +V VPM+ + D SV + A Sbjct: 169 FKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDA 228 Query: 332 TLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPR----AIRLTLPQLEIRGSYNLQDLL 387 T+ I P+ + +E ++ L+ W R + L LP+ I GSY L +L Sbjct: 229 TVFFILPN-QGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQIL 287 Query: 388 AEDKLPTLLGAEANLSNIGDTN-PRVGEVLNSILLELK 424 L A+LS I + + L++ Sbjct: 288 PRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVD 325 >1QMB-A nrPDB Length = 326 Score = 308 bits (788), Expect = 4e-84, Method: Composition-based stats. Identities = 70/336 (20%), Positives = 137/336 (40%), Gaps = 23/336 (6%) Query: 104 VGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTS 163 F +Y+ L ++ SP ++ LG+ T ++ L+ + E Sbjct: 9 FAFSLYRQLA--HQSSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTE---IP 63 Query: 164 RLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSL-ALFTP 222 H+ Q LL T SQ L + GLF + G +L F++ + L+ Sbjct: 64 EAAIHE------GFQELLRTLNQPDSQLQL--TTGNGLFLSEGLKLVDKFLEDVKKLYHS 115 Query: 223 ALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMRGF 282 F + D A ++IN +++ T K+ ++ + D+ Y+ F+G Sbjct: 116 EAFTVNF---GDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERP 172 Query: 283 SQL--PGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATLLLIQPHC 340 ++ +F VD +V VPM+ G F + + V + AT + P Sbjct: 173 FEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPD- 231 Query: 341 TSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEA 400 L +E + + + ++EN R+ L LP+L I G+Y+L+ +L + + + A Sbjct: 232 EGKLQHLENELTHDIITKFLEN-DRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGA 290 Query: 401 NLSNIGDTNP-RVGEVLNSILLEL-KAGEEEQPTTS 434 +LS + + P ++ + ++ +L + + G E Sbjct: 291 DLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMF 326 >4AJU-A nrPDB Length = 387 Score = 307 bits (786), Expect = 8e-84, Method: Composition-based stats. Identities = 71/354 (20%), Positives = 133/354 (37%), Gaps = 29/354 (8%) Query: 94 AAQVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLD 153 Q+A + GF + + ++ G + SP + + LG+ PT +Q++ L Sbjct: 51 RQQLAKETSNFGFSLLRKISMRHDG--NMVFSPFGMSLAMTGLMLGATGPTETQIKRGLH 108 Query: 154 V----PVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRL 209 + P K G S G + + GL F F + Sbjct: 109 LQALKPTKPGLLPSLFKGLRETLSRNLELGLTQ---------------GSFAFIHKDFDV 153 Query: 210 KHSFVQ-SLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLL 268 K +F S F P + + A +N +I T K+ + ++ ++ L+ Sbjct: 154 KETFFNLSKRYFDTECVPMNF---RNASQAKRLMNHYINKETRGKIPKLFDEINPETKLI 210 Query: 269 FNTYVHFQGTMRGFSQL--PGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVP 326 Y+ F+G V F +D ++ VPM+ G G F D V +P Sbjct: 211 LVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLP 270 Query: 327 LGERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDL 386 AT+L++ D +E + + + TW+ N R + + P+ ++ Y + +L Sbjct: 271 YQGNATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHEL 330 Query: 387 LAEDKLPTLLGAEANLSNIGDT--NPRVGEVLNSILLELKAGEEEQPTTSVQQP 438 L + + + A+LS + T N +V VL ++E+ E + + Sbjct: 331 LRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEI 384 >2R9Y-A nrPDB Length = 430 Score = 303 bits (776), Expect = 1e-82, Method: Composition-based stats. Identities = 91/392 (23%), Positives = 145/392 (36%), Gaps = 35/392 (8%) Query: 87 EDEDRKRAAQVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTAS 146 E+ +R AQ M F + S +S +LSP ++ L LG+ + T Sbjct: 14 TAEETRRLAQAMMAFTTDLFSLVAQ----TSTSSNLVLSPLSVALALSHLALGAQNQTLH 69 Query: 147 QLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPG 206 L +L + G C L H Q L P + ++ G Sbjct: 70 SLHRVLHMN--TGSCLPHLLSH-------FYQNL----------GPGTIRLAARIYLQKG 110 Query: 207 FRLKHSFV-QSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDS 265 F +K F+ QS LF P L + LA IN+++K T K+ L + + Sbjct: 111 FPIKDDFLEQSERLFGAK--PVKLTGKQEEDLAN--INQWVKEATEGKIEDFLSELPDST 166 Query: 266 TLLFNTYVHFQGTMRGFSQL--PGVHEFWVDNSISVSVPMISGTGNFQHWSD-AQNNFSV 322 LL +HF G R F +D +VSV M+ W Q V Sbjct: 167 VLLLLNAIHFHGFWRTKFDPSLTQKDFFHLDERFTVSVDMMHAVSYPLRWFLLEQPEIQV 226 Query: 323 TCVPLGERATLLLIQP-HCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSY 381 P + +++ P + ++ V A + + L + + R ++ LP+L ++ Sbjct: 227 AHFPFKNNMSFVVVMPTYFEWNVSEVLANLTWDTL--YHPSLQERPTKVWLPKLHLQQQL 284 Query: 382 NLQDLLAEDKLPTLLGAEANLSNIGDTNPRVGEVLNSILLELKAGEEEQPTTSVQQPGSP 441 +L L++ L L +L I + N V V + +EL E + Sbjct: 285 DLVATLSQLGLQELF-QGPDLRGISEQNLVVSSVQHQSTMELSEAGVEAAAATSVAMNRM 343 Query: 442 EALDVTLSSPFLFAIYEQDSGTLHFLGRVNNP 473 T++ PFLF I E G F+G V NP Sbjct: 344 SLSSFTVNRPFLFFIMEDTIGVPLFVGSVRNP 375 >2XN5-A nrPDB Length = 350 Score = 298 bits (763), Expect = 3e-81, Method: Composition-based stats. Identities = 57/349 (16%), Positives = 123/349 (35%), Gaps = 22/349 (6%) Query: 104 VGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTS 163 F +Y+ SP ++ LV G+ T +++ L + + Sbjct: 18 FAFNLYRRFTVET-PDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVE 76 Query: 164 RLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLA-LFTP 222 G Q L+ + + L I LF + F+ + L+ Sbjct: 77 IQHG---------FQHLICSLNFPKKELEL--QIGNALFIGKHLKPLAKFLNDVKTLYET 125 Query: 223 ALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMRGF 282 +F ++ A ++IN ++ T K+ ++ + ++ ++ Y+HF+ Sbjct: 126 EVFSTDF---SNISAAKQEINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANP 182 Query: 283 SQLPGVHE---FWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATLLLIQPH 339 + F +D + +V VPM+ + H D + N +V + + A L + P Sbjct: 183 FDPSKTEDSSSFLIDKTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDYSKNALALFVLPK 242 Query: 340 CTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAE 399 ++ VEA + L W + L +P+ I +Y+L L + + Sbjct: 243 -EGQMESVEAAMSSKTLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSEN 301 Query: 400 ANLSNIGDTN-PRVGEVLNSILLEL-KAGEEEQPTTSVQQPGSPEALDV 446 A+ S + + N ++ + +L + + G E ++ Sbjct: 302 ADFSGLTEDNGLKLSNAAHKAVLHIGEKGTEAAGAMFLEAIPRSIPNTF 350 >4KDS-A nrPDB Length = 386 Score = 297 bits (760), Expect = 7e-81, Method: Composition-based stats. Identities = 86/383 (22%), Positives = 151/383 (39%), Gaps = 32/383 (8%) Query: 104 VGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTS 163 G R++ + + G S SP + L LG+ T L L ++E Sbjct: 22 FGMRVFSQVAQNSKG-SNLAFSPYGVATILAMAQLGAGGNTLKTLNAKLGFSLQE----- 75 Query: 164 RLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLALFTPA 223 + Q LL S L G+ L+ F + L A Sbjct: 76 --------RGMARQQRLLQRDISSEEGVEL----ASGVMVERKMALEKGFRRGLGKAFQA 123 Query: 224 LFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEG--VSTDSTLLFNTYVHFQGTMRG 281 P LD S P A + IN ++ T + L ++ ++ ++ +HFQG + Sbjct: 124 S-PHQLDFSR-PDQALDIINAWVSDHTAGTIPSFLSSGALTDETRMVLLNALHFQGLWKV 181 Query: 282 FSQLPGVHE--FWVDNSISVSVPMISGTGNFQHWSDAQ---NNFSVTCVPL-GERATLLL 335 E F N SV VPM+ T F++ ++ V VP GE ++LL Sbjct: 182 PFDPKMTEERLFHCANGSSVPVPMMRLTHRFKYGEFVTPDGVDYDVIEVPYEGESLSMLL 241 Query: 336 IQP-HCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPT 394 + P + + + + + L W + +L LP+ + L+ +L + L Sbjct: 242 VSPFEPETPVSSLSSELTTQRLQQWRQEMRSVKRQLVLPRFTLDSEVELKSILIQMGLGD 301 Query: 395 LLG-AEANLSNIGDTNPR-VGEVLNSILLEL-KAGEEEQPTTSVQQPGSPEALDVTLSSP 451 + A+A+ + I P V +VL + +E+ + G + T+ ++T++ P Sbjct: 302 MFNLAKADFTRITTEQPLCVSKVLQKVKIEVNEEGTKASAATAAILFSRMAVEEITMNRP 361 Query: 452 FLFAIYEQDSGTLHFLGRVNNPQ 474 FLF I+ + +G + F+G+VN PQ Sbjct: 362 FLFLIHHKSTGAVLFMGQVNQPQ 384 >4GA7-A nrPDB Length = 389 Score = 294 bits (753), Expect = 5e-80, Method: Composition-based stats. Identities = 72/394 (18%), Positives = 146/394 (37%), Gaps = 33/394 (8%) Query: 96 QVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVP 155 Q++ ++ L+E + A +SP ++ + +LG+ TA+QL Sbjct: 13 QLSSANTRFALDLFLALSE-NNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFN 71 Query: 156 VKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQ 215 E Q L + L + L+ + F+ Sbjct: 72 TVEE-------------VHSRFQSLNADINKRGASYIL--KLANRLYGEKTYNFLPEFLV 116 Query: 216 SLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEG--VSTDSTLLFNTYV 273 S A S+D A + IN+++K T K+ L V + L+ + Sbjct: 117 STQKTYGADLA-SVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAI 175 Query: 274 HFQGTMR--GFSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGE-R 330 +F+G + + F ++ +V M+ F + V +P Sbjct: 176 YFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEE 235 Query: 331 ATLLLIQP----HCTSDLDRVEALIFRNDLLTWIE--NPPPRAIRLTLPQLEIRGSYNLQ 384 +++++ P ++ L ++E + L W + N + ++LP+ ++ SY L Sbjct: 236 LSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLN 295 Query: 385 DLLAEDKLPTLL-GAEANLSNI-GDTNPRVGEVLNSILLELKAGEEEQPTTSVQQPG--S 440 LA + L ++A+LS + G + + ++++ +E+ E + Sbjct: 296 SDLARLGVQDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCM 355 Query: 441 PEALD-VTLSSPFLFAIYEQDSGTLHFLGRVNNP 473 + + T PFLF I SG++ FLGR ++P Sbjct: 356 DDPEENFTADHPFLFFIRHNSSGSILFLGRFSSP 389 >4DY0-A nrPDB Length = 379 Score = 290 bits (742), Expect = 1e-78, Method: Composition-based stats. Identities = 72/387 (18%), Positives = 155/387 (40%), Gaps = 35/387 (9%) Query: 102 NFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDC 161 + G +++ + ++ ++SP + L LG+ T QL ++ V Sbjct: 13 SNTGIQVFNQIVKSR-PHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGV----- 66 Query: 162 TSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFV-QSLALF 220 + V L+ + +V++ + ++ +F ++ FV ++ +F Sbjct: 67 ------NGVGKILKKINKAIVSKKNKD-----IVTVANAVFVKNASEIEVPFVTRNKDVF 115 Query: 221 TPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTD---STLLFNTYVHFQG 277 + + DP A + IN ++K T ++ L D + L+ V+F+G Sbjct: 116 QCEVRNVNF---EDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKG 172 Query: 278 TMRGFSQLPGVHE--FWVDNSISVSVPMISGTGNFQHWSDAQNN---FSVTCVPL-GERA 331 + Q + F + S VPM++ F+ S + N ++ +P GE Sbjct: 173 LWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESI 232 Query: 332 TLLLIQP-HCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAED 390 ++L+ P ++ L + I + +W+ P+ +++ LP+ +L++ L Sbjct: 233 SMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVL 292 Query: 391 KLPTLL-GAEANLSNI--GDTNPRVGEVLNSILLEL-KAGEEEQPTTSVQQPGSPEALDV 446 + + ++AN + I G N V +L +E+ + G + T+ Sbjct: 293 GITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWF 352 Query: 447 TLSSPFLFAIYEQDSGTLHFLGRVNNP 473 + PFLF I +G + F+G++N P Sbjct: 353 IVDRPFLFFIRHNPTGAVLFMGQINKP 379 >1IMV-A nrPDB Length = 398 Score = 283 bits (725), Expect = 8e-77, Method: Composition-based stats. Identities = 83/415 (20%), Positives = 167/415 (40%), Gaps = 25/415 (6%) Query: 65 AKTSPVNEKTLHDQLVLAAEKLEDEDRKRAAQVAMIANFVGFRMYKMLNEAGSGASGAIL 124 + P D E+ + + ++A + G+ +Y+ + + S + +L Sbjct: 2 PASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSNFGYDLYR-VRSSMSPTTNVLL 60 Query: 125 SPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQ 184 SP ++ L + LG+ + T S + L D S D H L + + Q Sbjct: 61 SPLSVATALSALSLGADERTESIIHRALYY-----DLISSPDIHGTYKEL--LDTVTAPQ 113 Query: 185 GGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKINR 244 S + R+K SFV L + R L+ +P L ++IN Sbjct: 114 KNLKS--------ASRIVFEKKLRIKSSFVAPLEK---SYGTRPRVLTGNPRLDLQEINN 162 Query: 245 FIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTM--RGFSQLPGVHEFWVDNSISVSVP 302 +++A K+ + + + ++L HF+G + S+ + +F++D +V VP Sbjct: 163 WVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVP 222 Query: 303 MISG-TGNFQHWSDAQNNFSVTCVPLGERATLLLIQP-HCTSDLDRVEALIFRNDLLTWI 360 M+S ++ D+ + + +PL +++ P T +L +E + + Sbjct: 223 MMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHDID 282 Query: 361 ENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNIGDTNPRVGEVLNSIL 420 LT+P+L++ + L E KL +L + + S I ++ +V + Sbjct: 283 RELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDS-PDFSKITGKPIKLTQVEHRAG 341 Query: 421 LELKAGEEE-QPTTSVQQPGSPEALDVTLSSPFLFAIYEQDSGTLHFLGRVNNPQ 474 E P+ +Q LD L+ PF+F + + D+G L F+G++ +P+ Sbjct: 342 FEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDPR 396 >4DTE-A nrPDB Length = 374 Score = 282 bits (722), Expect = 2e-76, Method: Composition-based stats. Identities = 82/383 (21%), Positives = 151/383 (39%), Gaps = 32/383 (8%) Query: 104 VGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTS 163 G +++ + LSP + L +G+ T L + + ++E Sbjct: 10 FGLQVFAE-AVQSAPDRNLALSPYGIASVLGMAQMGAYGATLKLLASKMGYSLQE----- 63 Query: 164 RLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLALFTPA 223 + +Q LL S + G+ L+ F +SL+ + Sbjct: 64 --------RGMPKLQRLLQRDLASEDGVE----VASGVMVDRKIILEKVFRRSLSKAFQS 111 Query: 224 LFPRSLDLSTDPVLATEKINRFIKAVTGWKMN--LPLEGVSTDSTLLFNTYVHFQGTMRG 281 P +D S P +A + IN + T ++ LP +S + L+F +HF G + Sbjct: 112 -VPHQIDFSQ-PEMARQVINSWTSDHTDGMISEFLPSGVLSELTRLVFLNALHFHGVWKT 169 Query: 282 FSQLPGVHE--FWVDNSISVSVPMISGTGNFQHW---SDAQNNFSVTCVPL-GERATLLL 335 E F N +VSVPM++ T F + S ++ V +P GE ++LL Sbjct: 170 PFDPRNTREQLFHTVNGSAVSVPMMTTTQKFNYGEFVSKDGVDYDVIEMPYEGESISMLL 229 Query: 336 IQPHCTS-DLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPT 394 + P L + + + + W + + +L++P+ + +L+ L+ L Sbjct: 230 VTPFEKDVPLSALNKELSSSRIHQWRQEMRKISKQLSIPRFSMDTEIDLKSTLSRMGLGD 289 Query: 395 LLG-AEANLSNIGDTNPR-VGEVLNSILLEL-KAGEEEQPTTSVQQPGSPEALDVTLSSP 451 + + A+ S I P V +VL + LE+ + G + T+ ++TL P Sbjct: 290 IFSQSRADFSRITTEEPLCVSKVLQRVKLEVNEEGTKGSSATAAVIYSRMAVEEITLDRP 349 Query: 452 FLFAIYEQDSGTLHFLGRVNNPQ 474 F F I + +G L F G++ PQ Sbjct: 350 FFFLIQHKPTGALLFSGQLTQPQ 372 >3F02-A nrPDB Length = 359 Score = 276 bits (707), Expect = 1e-74, Method: Composition-based stats. Identities = 56/350 (16%), Positives = 130/350 (37%), Gaps = 29/350 (8%) Query: 104 VGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTS 163 + MY L A + SP ++ + LG+ T +++ + Sbjct: 26 LSVNMYNRLR-ATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDS------- 77 Query: 164 RLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLALFTPA 223 L + + L+ ++ + ++ + I LF GF + F+Q + + A Sbjct: 78 -LKNGEEFSFLKEFSNMVT-----AKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNA 131 Query: 224 LFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLE--GVSTDSTLLFNTYVHFQGTMRG 281 +D S + +A IN++++ T + + + L V+F+G + Sbjct: 132 AVNH-VDFSQNVAVAN-YINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKS 189 Query: 282 FSQL--PGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNN------FSVTCVPLGER-AT 332 + F D+ V +PM+ G F + + + + V +P + Sbjct: 190 QFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEIS 249 Query: 333 LLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKL 392 ++L+ L +E L+ + W + + + + LP+ + +L+D+L + Sbjct: 250 MMLVLSRQEVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGI 309 Query: 393 PTLLGAEANLSNIGD-TNPRVGEVLNSILLEL-KAGEEEQPTTSVQQPGS 440 + +ANL+ + D + + ++ LE+ + G E + + Sbjct: 310 TEIFIKDANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISR 359 >4P0F-A nrPDB Length = 393 Score = 276 bits (707), Expect = 1e-74, Method: Composition-based stats. Identities = 73/391 (18%), Positives = 150/391 (38%), Gaps = 34/391 (8%) Query: 96 QVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVP 155 + A +Y L+ G + SP ++ LG+ + TA+QL L + Sbjct: 9 EFARRLALFSINVYGKLSGQKPGE-NIVFSPFSIQTCAAMARLGAENETATQLDQGLGLA 67 Query: 156 VKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQ 215 + + + H+VLAA + Q L I +F G++L+ F Q Sbjct: 68 SSDPEQIAH-SFHQVLAAYQDSQIL---------------RIANKIFVMDGYQLRQEFDQ 111 Query: 216 SLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPL--EGVSTDSTLLFNTYV 273 L+ + +S+D S + V A IN +++ T + + + ++++S L+ + Sbjct: 112 LLSKQFLSA-AQSVDFSKN-VQAAATINNWVEQRTNHLIKDLVPADVLNSESRLVLVNAI 169 Query: 274 HFQGTMRGFS--QLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGE-R 330 HF+GT + L F +D +V VPM+S F++ + +P + Sbjct: 170 HFKGTWQHQFAKHLTRPDTFHLDGERTVQVPMMSLKERFRYADLPALDAMALELPYKDSD 229 Query: 331 ATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAED 390 ++L++ P+ + L +E + L ++ + L LP+ + L ++ + Sbjct: 230 LSMLIVLPNTKTGLPALEEKLRLTTLSQITQSLYETKVALKLPRFKAEFQVELSEVFQKL 289 Query: 391 KLPTLLGAEANLSNI--GDTNPRVGEVLNSILLEL-KAGEEEQPTTS------VQQPGSP 441 + + +A + +V +++ +E+ + G E T Sbjct: 290 GMSRMFSDQAEFGKMLQSPEPLKVSAIIHKAFIEVNEEGTEAAAATGMAVRRKRAIMSPE 349 Query: 442 EALDVTLSSPFLFAIYEQDSGTLHFLGRVNN 472 E ++ PF + + Q F G V Sbjct: 350 EPIEFFADHPFTYVLVHQK-DLPLFWGSVVR 379 >2H4P-A nrPDB Length = 394 Score = 269 bits (688), Expect = 2e-72, Method: Composition-based stats. Identities = 58/382 (15%), Positives = 135/382 (35%), Gaps = 38/382 (9%) Query: 87 EDEDRKRAAQVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTAS 146 E QV+ ++ LNE + SP ++ L YL + TA Sbjct: 19 SHELEISMEQVSASIGNFTVDLFNKLNE-TNRDKNIFFSPWSISSALALTYLAAKGSTAR 77 Query: 147 QLQTLLDV------------------PVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSS 188 ++ +L P + + + + + + Sbjct: 78 EMAEVLHFTEAVRAESSSVARPSRGRPKRRRMDPEHEQAENIHSGFKELLTAFNKPRNNY 137 Query: 189 SQTPLLQSIMVGLFTAPGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKA 248 S ++ + L +++Q + A P+ ++ T P + ++IN +++ Sbjct: 138 S-----LRSANRIYVEKTYALLPTYLQLSKKYYKAE-PQKVNFKTAPEQSRKEINTWVEK 191 Query: 249 VTGWKMNLPL--EGVSTDSTLLFNTYVHFQGTM--RGFSQLPGVHEFWVDNSISVSVPMI 304 T K+ L + V + L+ ++F+ + ++ + F + + S V M+ Sbjct: 192 QTESKIKNLLSSDDVKATTRLILVNAIYFKAEWEVKFQAEKTSIQPFRLSKNKSKPVKMM 251 Query: 305 SGTGNFQHWSDAQNNFSVTCVPLGE-RATLLLIQPHCTSD----LDRVEALIFRNDLLTW 359 F + NF + +P + ++ ++ P D L+++E + L W Sbjct: 252 YMRDTFPVLIMEKMNFKMIELPYVKRELSMFILLPDDIKDGTTGLEQLERELTYERLSEW 311 Query: 360 IEN--PPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNIGD-TNPRVGEVL 416 ++ + L LP+ + +L+D L + T A+ + D + + +V+ Sbjct: 312 ADSKMMTETLVDLHLPKFSLEDRIDLRDTLRNMGMTTAFTTNADFRGMTDKKDLAISKVI 371 Query: 417 NSILLEL-KAGEEEQPTTSVQQ 437 + + + + G E T+V Sbjct: 372 HQSFVAVDEKGTEAAAATAVII 393 >2H4Q-A nrPDB Length = 382 Score = 269 bits (687), Expect = 2e-72, Method: Composition-based stats. Identities = 59/355 (16%), Positives = 132/355 (37%), Gaps = 30/355 (8%) Query: 96 QVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVP 155 QV+ ++ LNE + SP ++ L YL + TA ++ +L Sbjct: 44 QVSASIGNFTVDLFNKLNE-TNRDKNIFFSPWSISSALALTYLAAKGSTAREMAEVLHFE 102 Query: 156 VKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQ 215 E + LL + L ++ + L +++Q Sbjct: 103 QAEN-------------IHSGFKELLTAFNKPRNNYSL--RSANRIYVEKTYALLPTYLQ 147 Query: 216 SLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPL--EGVSTDSTLLFNTYV 273 + A P+ ++ T P + ++IN +++ T K+ L + V + L+ + Sbjct: 148 LSKKYYKAE-PQKVNFKTAPEQSRKEINTWVEKQTESKIKNLLSSDDVKATTRLILVNAI 206 Query: 274 HFQGTM--RGFSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGE-R 330 +F+ + ++ + F + + S V M+ F + NF + +P + Sbjct: 207 YFKAEWEVKFQAEKTSIQPFRLSKNKSKPVKMMYMRDTFPVLIMEKMNFKMIELPYVKRE 266 Query: 331 ATLLLIQPHCTSD----LDRVEALIFRNDLLTWIEN--PPPRAIRLTLPQLEIRGSYNLQ 384 ++ ++ P D L+++E + L W ++ + L LP+ + +L+ Sbjct: 267 LSMFILLPDDIKDGTTGLEQLERELTYERLSEWADSKMMTETLVDLHLPKFSLEDRIDLR 326 Query: 385 DLLAEDKLPTLLGAEANLSNIGD-TNPRVGEVLNSILLEL-KAGEEEQPTTSVQQ 437 D L + T A+ + D + + +V++ + + + G E T+V Sbjct: 327 DTLRNMGMTTAFTTNADFRGMTDKKDLAISKVIHQSFVAVDEKGTEAVAATAVII 381 >1HLE-A nrPDB Length = 345 Score = 268 bits (685), Expect = 3e-72, Method: Composition-based stats. Identities = 63/343 (18%), Positives = 134/343 (39%), Gaps = 32/343 (9%) Query: 96 QVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVP 155 Q++ +++ LNE+ +SP ++ L +LG+ TA+Q+ L Sbjct: 4 QLSTANTHFAVDLFRALNES-DPTGNIFISPLSISSALAMIFLGTRGNTAAQVSKALYFD 62 Query: 156 VKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQ 215 E D H +L A P + + L+ + F+ Sbjct: 63 TVE-------DIHSRFQSLNADIN--------KPGAPYILKLANRLYGEKTYNFLADFLA 107 Query: 216 SL-ALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPL--EGVSTDSTLLFNTY 272 S ++ L S+D P A ++IN ++K T K+ L V + L+ Sbjct: 108 STQKMYGAELA--SVDFQQAPEDARKEINEWVKGQTEGKIPELLVKGMVDNMTKLVLVNA 165 Query: 273 VHFQGTM--RGFSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGE- 329 ++F+G + + F ++ + +V M+ F + V +P Sbjct: 166 IYFKGNWQQKFMKEATRDAPFRLNKKDTKTVKMMYQKKKFPYNYIEDLKCRVLELPYQGK 225 Query: 330 RATLLLIQP----HCTSDLDRVEALIFRNDLLTWIE--NPPPRAIRLTLPQLEIRGSYNL 383 +++++ P ++ L+++E + + L W + N + + LP+ ++ SY+L Sbjct: 226 ELSMIILLPDDIEDESTGLEKIEKQLTLDKLREWTKPENLYLAEVNVHLPRFKLEESYDL 285 Query: 384 QDLLAEDKLPTLLG-AEANLSNI-GDTNPRVGEVLNSILLELK 424 LA + L +A+LS + G + V ++++ ++L Sbjct: 286 TSHLARLGVQDLFNRGKADLSGMSGARDLFVSKIIHKSFVDLN 328 >1C5G-A nrPDB Length = 402 Score = 267 bits (683), Expect = 7e-72, Method: Composition-based stats. Identities = 72/390 (18%), Positives = 145/390 (37%), Gaps = 31/390 (7%) Query: 97 VAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPV 156 VA +A+ G R+++ + +A S + SP + L L + T Q+Q + + Sbjct: 31 VAHLASDFGVRVFQQVAQA-SKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKI 89 Query: 157 KEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFV-Q 215 + L + L+ S +F +L F+ Sbjct: 90 DDKGMAPAL--------RHLYKELMGPWNKD------EISTTDAIFVQRDLKLVQGFMPH 135 Query: 216 SLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLE--GVSTDSTLLFNTYV 273 LF + + +D S + A IN ++K T ++ L V + L+ + Sbjct: 136 FFRLFRSTV--KQVDFS-EVERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNAL 192 Query: 274 HFQGTMRGFSQLPGVHE--FWVDNSISVSVPMISGTGNFQHWSDAQNN---FSVTCVPLG 328 +F G + H F + +VSVPM++ T F + + + + +P Sbjct: 193 YFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYH 252 Query: 329 ER-ATLLLIQP-HCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDL 386 ++ + P L + ++ + W N L LP+ + +L+ Sbjct: 253 GDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKP 312 Query: 387 LAEDKLPTLLGA-EANLSNIGDTNP-RVGEVLNSILLELKA-GEEEQPTTSVQQPGSPEA 443 L + + +A+ +++ D P V + L + +E+ G +T+V Sbjct: 313 LENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAP 372 Query: 444 LDVTLSSPFLFAIYEQDSGTLHFLGRVNNP 473 ++ + PFLF + +GT+ F+G+V P Sbjct: 373 EEIIMDRPFLFVVRHNPTGTVLFMGQVMEP 402 >2OAY-A nrPDB Length = 390 Score = 261 bits (667), Expect = 4e-70, Method: Composition-based stats. Identities = 74/381 (19%), Positives = 156/381 (40%), Gaps = 38/381 (9%) Query: 104 VGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTS 163 ++Y + + SP ++ L LG+ + T + L+++L P K+ C Sbjct: 39 FSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYP-KDFTCVH 97 Query: 164 RLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQ-SLALFTP 222 +A++G S SQ +F +P ++ +FV S L++ Sbjct: 98 -----------QALKGFTTKGVTSVSQ----------IFHSPDLAIRDTFVNASRTLYSS 136 Query: 223 ALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMRGF 282 + PR L ++D L E IN ++ T K++ L+ + +D+ L+ ++ + Sbjct: 137 S--PRVLSNNSDANL--ELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTT 192 Query: 283 SQL--PGVHEFWVDNSISVSVPMISGTGN-FQHWSDAQNNFSVTCVPLGERATLLLIQP- 338 + F + + VPM++ H+ D V + L +L+++ P Sbjct: 193 FDPKKTRMEPFHF-KNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQ 251 Query: 339 ---HCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTL 395 H D+++ + ++ +E + LTLP++++ S ++ ++ + + Sbjct: 252 NLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFD- 310 Query: 396 LGAEANLSNIG-DTNPRVGEVLNSILLELKAGEEEQPTTSVQQPGSPEALDVTLSSPFLF 454 + NL + D + +V + + +LEL E S L + PFLF Sbjct: 311 FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVAR-TLLVFEVQQPFLF 369 Query: 455 AIYEQDSGTLHFLGRVNNPQS 475 +++Q F+GRV +P++ Sbjct: 370 MLWDQQHKFPVFMGRVYDPRA 390 >3ZHA-A nrPDB Length = 392 Score = 261 bits (667), Expect = 5e-70, Method: Composition-based stats. Identities = 80/389 (20%), Positives = 160/389 (41%), Gaps = 24/389 (6%) Query: 93 RAAQVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLL 152 +AA +A + + F +Y+ + + + +LSP + +L LG TASQ + +L Sbjct: 5 KAATLAERSAGLAFSLYQAMAKDQAVE-NILLSPVVVASSLGLVSLGGKATTASQAKAVL 63 Query: 153 DVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHS 212 + A G L+ +S+ + + L+ Sbjct: 64 SAEQLRDEEV------------HAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFAED 111 Query: 213 FVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTY 272 FV+S ++ D A + IN + T K+ + V L Sbjct: 112 FVRSSKQHYN-CEHSKINF-RDKRSALQSINEWAAQTTDGKLPEVTKDVERTDGALLVNA 169 Query: 273 VHFQGTM--RGFSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGER 330 + F+ + ++ F V S +V V M+ TG + ++ D + + +PL + Sbjct: 170 MFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVTMMHRTGLYNYYDDEKEKLQIVEMPLAHK 229 Query: 331 AT-LLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAE 389 + L+++ PH L+R+E L+ + L W+ +A+ ++LP+ + +++LQ LA Sbjct: 230 LSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAG 289 Query: 390 DKLPTLLGA-EANLSNI-GDTNPRVGEVLNSILLEL--KAGEEEQPTTSVQQPGSPEALD 445 L + +A+LS + G + + V ++ E + +Q ++ SP+ Sbjct: 290 LGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFEWDTEGNPFDQDIYGREELRSPKL-- 347 Query: 446 VTLSSPFLFAIYEQDSGTLHFLGRVNNPQ 474 PF+F + + SG+L F+GR+ P+ Sbjct: 348 FYADHPFIFLVRDTQSGSLLFIGRLVRPK 376 >3LW2-A nrPDB Length = 379 Score = 258 bits (660), Expect = 3e-69, Method: Composition-based stats. Identities = 70/393 (17%), Positives = 142/393 (36%), Gaps = 29/393 (7%) Query: 93 RAAQVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLL 152 R + A A G ++++ + +A S + SP + L + + T Q+Q + Sbjct: 4 RESHTAHQATDFGVKVFQQVVQA-SKDRNVVFSPYGVSSVLAMLQMTTAGKTRRQIQDAM 62 Query: 153 DVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHS 212 V E ALR + L+ + S +F L Sbjct: 63 GFKVNEK---------GTAHALRQLSKELMGPWNKN-----EISTADAIFVQRDLELVQG 108 Query: 213 FVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPL--EGVSTDSTLLFN 270 F+ + + +D S + A IN +++ T +N L V + L+ Sbjct: 109 FMPHFFKLFQTMV-KQVDFS-EVERARFIINDWVERHTKGMINDLLAKGAVDELTRLVLV 166 Query: 271 TYVHFQGTMRGFSQLPGVHE--FWVDNSISVSVPMISGTGNFQHWSDAQ---NNFSVTCV 325 ++F G + H+ F + +VSVPM++ + F + + V + Sbjct: 167 NALYFSGQWKTPFLEASTHQRLFHKSDGSTVSVPMMAQSNKFNYTEFTTPDGLEYDVVEL 226 Query: 326 PLGER-ATLLLIQPHCTS-DLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNL 383 P ++ + P L + ++ + W N L LP+ + +L Sbjct: 227 PYQGDTLSMFIAAPFEKDVHLSALTNILDAELIRQWKGNMTRLPRLLILPKFSLETEVDL 286 Query: 384 QDLLAEDKLPTLLGAE-ANLSNIGD-TNPRVGEVLNSILLELKA-GEEEQPTTSVQQPGS 440 + L + +P + A A+ +++ D V + L + +E+ G +T+ Sbjct: 287 RGPLEKLGMPDMFSATLADFTSLSDQEQLSVAQALQKVRIEVNESGTVASSSTAFVISAR 346 Query: 441 PEALDVTLSSPFLFAIYEQDSGTLHFLGRVNNP 473 ++ + FLF + + T+ F+G+V P Sbjct: 347 MAPTEMVIDRSFLFVVRHNPTETILFMGQVMEP 379 >1C8O-A nrPDB Length = 300 Score = 255 bits (652), Expect = 3e-68, Method: Composition-based stats. Identities = 71/339 (20%), Positives = 135/339 (39%), Gaps = 48/339 (14%) Query: 107 RMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPV-KEGDCTSRL 165 +++ + + G +SPP++ L Y G+ TA QL ++ K D S Sbjct: 2 DIFREIASSMKGE-NVFISPPSISSVLTILYYGANGSTAEQLSKYVEKEADKNKDDISFK 60 Query: 166 DGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLAL-FTPAL 224 +KV AV K SF++ + F Sbjct: 61 SMNKVYGRYSAV-------------------------------FKDSFLRKIGDNFQTVD 89 Query: 225 FPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPL-EGVSTDSTLLFNTYVHFQGTM--RG 281 F S + IN+ + T K+N L E +S D++LL + V+F+ Sbjct: 90 FTDSR--------TVDAINKSVDIFTEGKINPLLDEPLSPDTSLLAISAVYFKAKWLMPF 141 Query: 282 FSQLPGVHEFWVDNSISVSVPMISGTGN-FQHWSDAQN--NFSVTCVPLGERATLLLIQP 338 + + F+V + V V M+S G F H S ++ NFS+ +P ++++I P Sbjct: 142 EKEFTSDYPFYVSPTEMVDVSMMSMYGEAFNHASVKESFGNFSIIELPYVGDTSMVVILP 201 Query: 339 HCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGA 398 L+ +E + + W ++ I + +P+ ++ GSYNL D L + L + G+ Sbjct: 202 DNIDGLESIEQNLTDTNFKKWSDSMDAMFIDVHIPKFKVTGSYNLVDALVKLGLTEVFGS 261 Query: 399 EANLSNIGDTNPRVGEVLNSILLELKAGEEEQPTTSVQQ 437 + SN+ +++ V +++ +++ E + Sbjct: 262 TGDYSNMSNSDVSVDAMIHKTYIDVNEEYTEAAAATSAL 300 >6CJ7-A nrPDB Length = 390 Score = 253 bits (646), Expect = 1e-67, Method: Composition-based stats. Identities = 68/393 (17%), Positives = 150/393 (38%), Gaps = 35/393 (8%) Query: 94 AAQVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLD 153 A + G ++K + SG SP ++ L G+ T ++ L Sbjct: 10 AIHSGPASTSFGVNVFKQMATEQSG--NLAASPFSITILLAMLQQGAAGNTLDEITRALQ 67 Query: 154 VPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSF 213 + ++ + + +S+ L +F + F L F Sbjct: 68 MTPEKSAEI--------------FKKVNEEIQKRNSRNIL--KTANNVFLSENFNLNPQF 111 Query: 214 VQ-SLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLP--LEGVSTDSTLLFN 270 + ++ F L P P LA + IN +I + T K++ + +S ++ ++ Sbjct: 112 KRIAVNNFDSDLTPTYF---GKPALAAQNINSWIASKTNDKIDKLVSPDDLSGNTQMVMV 168 Query: 271 TYVHFQGTMRGFS--QLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLG 328 V+F+G Q F ++ + F+ + V +P Sbjct: 169 NAVYFKGLWEIPFREQATQKRNFTLNGGEKKVASFMQTRRYFKAGTHKPAMAKVVVLPFE 228 Query: 329 ER-ATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLL 387 +L+++ P +S++D + + + D+ ++++ PP+ + L LP+ I+ NL+ +L Sbjct: 229 YNEYSLIVVLPLKSSNVDALLSSLSMEDVASFLD-LPPKDVALELPKFSIKADINLEPVL 287 Query: 388 AEDKLPTLLGAEANLSNIGDT---NPRVGEVLNSILLELKAGEEEQPTTSVQQPGS---- 440 + + ++ +A L N+G +P+V L+S +L + + + Sbjct: 288 NKMGVSSIFTQQAELYNLGSHGSLSPQVSSALHSAVLTIDERGGSAAAATSFAAVALSYD 347 Query: 441 PEALDVTLSSPFLFAIYEQDSGTLHFLGRVNNP 473 +L + PFL +++ S F+ R+ +P Sbjct: 348 EPSLYFRANKPFLAILWDNRSSIPLFMARIMDP 380 >1JJO-C nrPDB Length = 261 Score = 238 bits (607), Expect = 4e-63, Method: Composition-based stats. Identities = 45/263 (17%), Positives = 102/263 (38%), Gaps = 15/263 (5%) Query: 190 QTPLLQSIMVGLFTAPGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKAV 249 + + + LF GF + F+Q L ++ A +D S + +A IN++++ Sbjct: 1 ENQYVMKLANSLFVQNGFHVNEEFLQMLKMYFNAEVNH-VDFSQNVAVAN-SINKWVENY 58 Query: 250 TGWKMNLP--LEGVSTDSTLLFNTYVHFQGTMRGFSQL--PGVHEFWVDNSISVSVPMIS 305 T + E + L V+F+G + + F D+ V +PM+ Sbjct: 59 TNSLLKDLVSPEDFDGVTNLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMY 118 Query: 306 GTGNFQHWSDAQNN------FSVTCVPLGER-ATLLLIQPHCTSDLDRVEALIFRNDLLT 358 G F + + + + V +P +++L L +E L+ + Sbjct: 119 QQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLALSRQEVPLATLEPLLKAQLIEE 178 Query: 359 WIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNIGD-TNPRVGEVLN 417 W + + + + LP+ + +L+D+L + + +ANL+ + D + + ++ Sbjct: 179 WANSVKKQKVEVYLPRFTVEQEIDLKDILKALGVTEIFIKDANLTAMSDKKELFLSKAVH 238 Query: 418 SILLEL-KAGEEEQPTTSVQQPG 439 +E+ + G E + + Sbjct: 239 KSCIEVNEEGSEAAAASGMIAIS 261 >5NCS-A nrPDB Length = 375 Score = 232 bits (591), Expect = 3e-61, Method: Composition-based stats. Identities = 63/379 (16%), Positives = 142/379 (37%), Gaps = 30/379 (7%) Query: 102 NFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDC 161 N F + + + + +SP ++ L G+ TA +++T L + Sbjct: 12 NAFAFDLLQTTRK-HVTEANVFISPLSVSMALNMTLNGAAGVTADEMKTALRETGYTMED 70 Query: 162 TSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSF-VQSLALF 220 + H + AL V + ++ G +K F + + + Sbjct: 71 INEYS-HSLREALLKV------------DPSTTIGMANSIWYKQGELVKEPFILANRTHY 117 Query: 221 TPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMR 280 + +++D S+ L IN + T K+ L+ + ++ + V+F+G Sbjct: 118 DAEV--KAVDFSSPATLPA--INGWCAQKTNDKITKILDYIPGNAFMYLINAVYFKGIWV 173 Query: 281 GFSQLPGVH--EFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERA-TLLLIQ 337 + F + + V M++ F + +D + G +A +++++ Sbjct: 174 TQFKKSDTKRAPFRKADGTTQEVNMMAQKSTFGYTTDE--CCQYLEMDYGNKAFSMIVML 231 Query: 338 PHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNL-QDLLAEDKLPTLL 396 P+ V + I+ P + L +P+ + Y L + +L E + Sbjct: 232 PNEGQTTRDVIEQLDNKHWSMIIKGIRPTQVSLRMPRFKTECKYGLEKKILPEMGMNVPF 291 Query: 397 GAEANLSNIGDTNPRVGEVLNSILLEL-KAGEEEQPTTSVQQP----GSPEALDVTLSSP 451 A+ I D + V++ +++ + G E T+V+ S ++ ++ P Sbjct: 292 TETADFPGITDAAIFISRVIHKTFVQVDEEGTEAAAVTAVEMVKTSSPSTTPINFHINKP 351 Query: 452 FLFAIYEQDSGTLHFLGRV 470 F+FAI E+ +G + F+G + Sbjct: 352 FVFAIREKSTGVILFIGEI 370 >1XQJ-A nrPDB Length = 389 Score = 223 bits (569), Expect = 1e-58, Method: Composition-based stats. Identities = 71/406 (17%), Positives = 149/406 (36%), Gaps = 39/406 (9%) Query: 84 EKLEDEDRKRAAQVAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDP 143 E L + A Q+A A ++K L+E + SP AL +L +G+ Sbjct: 7 ENLYFQGSMDALQLANSA--FAVDLFKQLSE-KEPLGNVLFSPIALSTSLSLAQVGAKGD 63 Query: 144 TASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFT 203 TA+++ +L V Q + SS L ++ L+ Sbjct: 64 TANEIGQVLHFE-------------NVKDVPFGFQTVTSDVNKLSSFYSL--KLIKRLYV 108 Query: 204 APGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEG--V 261 L F+ S +D +IN IK +T L V Sbjct: 109 DKSLNLSTEFISSTKRPYAKELET-VDFKDKLEETKGQINNSIKDLTDGHFENILADNSV 167 Query: 262 STDSTLLFNTYVHFQGTM-RGFSQ-LPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNN 319 + + +L +F G + FS+ F V+ + + V M++ F + N Sbjct: 168 NDQTKILVVNAAYFVGKWMKKFSESETKESPFRVNKTDTKPVQMMNMEATFSMGNIDSIN 227 Query: 320 FSVTCVPLGER-ATLLLIQP----HCTSDLDRVEALIFRNDLLTWIE--NPPPRAIRLTL 372 + +P + ++ ++ P ++ L+++E + L W ++L++ Sbjct: 228 SKIIELPFQNKHLSMFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSI 287 Query: 373 PQLEIRGSYNLQDLLAEDKLPTLLGAE-ANLSNIGDTN-PRVGEVLNSILLELKAGEEEQ 430 P+ ++ + + L L + + ++ S + +T + V++ + LE+ E Sbjct: 288 PKFKVEKMIDPKASLENLGLKHIFSEDTSDFSGMSETKGVALSNVIHKVSLEI----TED 343 Query: 431 PTTSVQQPGSPEAL---DVTLSSPFLFAIYEQDSGTLHFLGRVNNP 473 S++ PG+ ++ PF++ I + + F G+ ++P Sbjct: 344 GGDSIEVPGARILQHKDELNADHPFIYIIRHNKTRNIIFFGKFSSP 389 >1M93-B nrPDB Length = 245 Score = 219 bits (557), Expect = 3e-57, Method: Composition-based stats. Identities = 54/249 (21%), Positives = 108/249 (43%), Gaps = 15/249 (6%) Query: 196 SIMVGLFTAPGFRLKHSFVQSLAL-FTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKM 254 M ++ K SF++ + F F S + IN+ + T K+ Sbjct: 5 KSMNKVYGRYSAVFKDSFLRKIGDNFQTVDFTDSR--------TVDAINKSVDIFTEGKI 56 Query: 255 NLPL-EGVSTDSTLLFNTYVHFQGTM--RGFSQLPGVHEFWVDNSISVSVPMISGTGN-F 310 N L E +S D++LL + V+F+ + + F+V + V V M+S G F Sbjct: 57 NPLLDEPLSPDTSLLAISAVYFKAKWLMPFEKEFTSDYPFYVSPTEMVDVSMMSMYGEAF 116 Query: 311 QHWSDAQN--NFSVTCVPLGERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAI 368 H S ++ NFS+ +P ++++I P L+ +E + + W ++ I Sbjct: 117 NHASVKESFGNFSIIELPYVGDTSMVVILPDNIDGLESIEQNLTDTNFKKWSDSMDAMFI 176 Query: 369 RLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNIGDTNPRVGEVLNSILLELKAGEE 428 + +P+ ++ GSYNL D L + L + G+ + SN+ +++ V +++ +++ Sbjct: 177 DVHIPKFKVTGSYNLVDALVKLGLTEVFGSTGDYSNMSNSDVSVDAMIHKTYIDVNEEYT 236 Query: 429 EQPTTSVQQ 437 E + Sbjct: 237 EAAAATSAL 245 >1SEK-A nrPDB Length = 378 Score = 206 bits (525), Expect = 1e-53, Method: Composition-based stats. Identities = 54/371 (14%), Positives = 132/371 (35%), Gaps = 34/371 (9%) Query: 116 GSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTSRLDGHKVLAALR 175 + +LS ++ L L S+ + +L L +P D ++ + A++ Sbjct: 29 ANPGQNVVLSAFSVLPPLGQLALASVGESHDELLRALALPNDNVTKDVFADLNRGVRAVK 88 Query: 176 AVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQ-SLALFTPALFPRSLDLSTD 234 V + ++ A G L F S +F + S + Sbjct: 89 GVD----------------LKMASKIYVAKGLELNDDFAAVSRDVFGSEVQNVDFVKSVE 132 Query: 235 PVLATEKINRFIKAVTGWKMNLPLEG--VSTDSTLLFNTYVHFQGTMR--GFSQLPGVHE 290 A IN++++ T ++ ++ + + + ++F+G+ + + + Sbjct: 133 AAGA---INKWVEDQTNNRIKNLVDPDALDETTRSVLVNAIYFKGSWKDKFNKERTMDRD 189 Query: 291 FWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGER-ATLLLIQPHCTSDLDRVEA 349 F V ++ VP + G + ++ + + + + A++++I P+ + +E Sbjct: 190 FHVSKDKTIKVPTMIGKKDVRYADVPELDAKMIEMSYEGDQASMIIILPNQVDGITALEQ 249 Query: 350 LIF-RNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAE-ANLSNI-- 405 + L E + + LP+ +I + +L+++L+ + L A L N+ Sbjct: 250 KLKDPKALSRAEERLYNTEVEIYLPKFKIETTTDLKEVLSNMNIKKLFTPGAARLENLLK 309 Query: 406 GDTNPRVGEVLNSILLELKAGEEEQPTTS---VQQPGSPEALDVTLSSPFLFAIYEQDSG 462 + V + +E+ E + + V ++ PF F++ + Sbjct: 310 TKESLYVDAAIQKAFIEVNEEGAEAAAANAFKITTYSFHFVPKVEINKPFFFSLKYNRNS 369 Query: 463 TLHFLGRVNNP 473 F G P Sbjct: 370 M--FSGVCVQP 378 >1K9O-I nrPDB Length = 378 Score = 205 bits (522), Expect = 3e-53, Method: Composition-based stats. Identities = 57/371 (15%), Positives = 134/371 (36%), Gaps = 34/371 (9%) Query: 116 GSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTSRLDGHKVLAALR 175 + +LS ++ L L S+ + +L L +P D ++ + A++ Sbjct: 29 ANPGQNVVLSAFSVLPPLGQLALASVGESHDELLRALALPNDNVTKDVFADLNRGVRAVK 88 Query: 176 AVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQ-SLALFTPALFPRSLDLSTD 234 V + ++ A G L F S +F + S + Sbjct: 89 GVD----------------LKMASKIYVAKGLELNDDFAAVSRDVFGSEVQNVDFVKSVE 132 Query: 235 PVLATEKINRFIKAVTGWKMNLPLEG--VSTDSTLLFNTYVHFQGTMR--GFSQLPGVHE 290 A IN++++ T ++ ++ + + + ++F+G+ + + + Sbjct: 133 AAGA---INKWVEDQTNNRIKNLVDPDALDETTRSVLVNAIYFKGSWKDKFVKERTMDRD 189 Query: 291 FWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGER-ATLLLIQPHCTSDLDRVEA 349 F V ++ VP + G + ++ + + + + A++++I P+ + +E Sbjct: 190 FHVSKDKTIKVPTMIGKKDVRYADVPELDAKMIEMSYEGDQASMIIILPNQVDGITALEQ 249 Query: 350 LIF-RNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAE-ANLSNI-- 405 + L E + +TLP+ +I + +L+++L+ + L A L N+ Sbjct: 250 KLKDPKALSRAEERLYNTEVEITLPKFKIETTTDLKEVLSNMNIKKLFTPGAARLENLLK 309 Query: 406 GDTNPRVGEVLNSILLELKAGEEEQPTT---SVQQPGSPEALDVTLSSPFLFAIYEQDSG 462 + V + +E+ E + +V + PF F + + G Sbjct: 310 TKESLTVDAAIQKAFIEVNEEGAEAAAANAFGIVPKSLILYPEVHIDRPFYFEL--KIDG 367 Query: 463 TLHFLGRVNNP 473 F G+V P Sbjct: 368 IPMFNGKVIEP 378 >3LE2-A nrPDB Length = 393 Score = 202 bits (514), Expect = 3e-52, Method: Composition-based stats. Identities = 68/397 (17%), Positives = 140/397 (35%), Gaps = 43/397 (10%) Query: 102 NFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDC 161 N V + K + S S I SP ++ L GS T Q+ + L + Sbjct: 13 NQVSMNLAKHVITTVSQNSNVIFSPASINVVLSIIAAGSAGATKDQILSFLKFSSTDQ-- 70 Query: 162 TSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLALFT 221 + + + S+ S+ G + K SF Q L Sbjct: 71 ----------LNSFSSEIVSAVLADGSANGGPKLSVANGAWIDKSLSFKPSFKQLLEDSY 120 Query: 222 PALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEG--VSTDSTLLFNTYVHFQGTM 279 A ++ D + V ++N + + T + L + + L+F ++F+GT Sbjct: 121 KAASNQA-DFQSKAVEVIAEVNSWAEKETNGLITEVLPEGSADSMTKLIFANALYFKGTW 179 Query: 280 --RGFSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPL-----GERAT 332 + L EF + + V+ P ++ + A + F V +P + + Sbjct: 180 NEKFDESLTQEGEFHLLDGNKVTAPFMTSKKK--QYVSAYDGFKVLGLPYLQGQDKRQFS 237 Query: 333 LLLIQPHCTSDLDRVEALI--FRNDLLTWIENPPPRAIRL---TLPQLEIRGSYNLQDLL 387 + P + L + I L + P R +++ +P+ + ++ ++L Sbjct: 238 MYFYLPDANNGLSDLLDKIVSTPGFLD---NHIPRRQVKVREFKIPKFKFSFGFDASNVL 294 Query: 388 AEDKLPTLLGAEANLSNIGDT-----NPRVGEVLNSILLEL-KAGEEEQPTTSVQQPGS- 440 L + E L+ + ++ N V + + +E+ + G E ++ Sbjct: 295 KGLGLTSPFSGEEGLTEMVESPEMGKNLCVSNIFHKACIEVNEEGTEAAAASAGVIKLRG 354 Query: 441 ----PEALDVTLSSPFLFAIYEQDSGTLHFLGRVNNP 473 + +D PFL + E +G + F+G+V +P Sbjct: 355 LLMEEDEIDFVADHPFLLVVTENITGVVLFIGQVVDP 391 >3OZQ-A nrPDB Length = 376 Score = 201 bits (511), Expect = 5e-52, Method: Composition-based stats. Identities = 58/386 (15%), Positives = 136/386 (35%), Gaps = 40/386 (10%) Query: 100 IANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEG 159 N +YK + + + ++SP + L G TA +++ +L Sbjct: 14 AVNSFTPSVYKEV--LKTEKANFLVSPFSAATLLALAQSGCRGDTAEEIRQVLHF----- 66 Query: 160 DCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQ-SLA 218 A AV+ +L ++ F ++ F + ++ Sbjct: 67 -------VGDREKAEGAVKEVLSKLTNE----EYTLHTANKIYVKTNFSVREEFQKIAVE 115 Query: 219 LFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEG--VSTDSTLLFNTYVHFQ 276 ++ D A + +N +++ T K+ ++ ++ + ++ ++F Sbjct: 116 VYGAQSENVDFSEKND---AAKLMNAWVEEQTQHKIQNLVDPEILNNLTRVVLINALYFN 172 Query: 277 GTMRGFSQL--PGVHEFWVDNSISVSVPMISG-TGNFQHWSDAQNNFSVTCVPLGERATL 333 +F V V + F ++ + + +P A+L Sbjct: 173 AKWLVPFPPFHTRKSDFHKSAKEVVQVDTMYLDEQYFNYYECHHLDAKLLELPFKGGASL 232 Query: 334 LLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLP 393 ++ + L +E+ I R+ L N + + + LP+ +I + + + +L + + Sbjct: 233 TIVLSNQIEGLVSLESKIKRSFLP---HNLTKQLVNVALPKFKIESTVDFKKVLKKLGVK 289 Query: 394 TLLGAEANLSNIG--DTNPRVGEVLNSILLEL-KAGEEEQPTTSVQQP----GSPEALD- 445 G EA+LS I + + ++ +++ + G E T + P++ Sbjct: 290 KAFGDEADLSGIAGEKGDLVISNIVQKSFIDVSEEGVEAAAATYIPVILPEMALPDSPKQ 349 Query: 446 VTLSSPFLFAIYEQDSGTLHFLGRVN 471 + PF+F I + G + F GRV Sbjct: 350 FIVDHPFIFYI--KVKGMILFAGRVT 373 >3PZF-A nrPDB Length = 397 Score = 199 bits (506), Expect = 2e-51, Method: Composition-based stats. Identities = 62/382 (16%), Positives = 129/382 (33%), Gaps = 25/382 (6%) Query: 106 FRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTSRL 165 F + + + S +LSP ++ L Y AS V + + +S + Sbjct: 25 FDLMFVKEIFKNHNSNVVLSPFSVKILLTLIY------EASDTSFGNAVSNTKRELSSVI 78 Query: 166 DGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQ-SLALFTPAL 224 + + LL + + L +I F + + + Q + + L Sbjct: 79 QNDNIDHTRSYYKQLLESAQQDNKDYDL--NIATNFFVDDFIEVINKYQQIANTHYHAML 136 Query: 225 FPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVS-TDSTLLFNTYVHFQGTMRGFS 283 S ++P IN ++ T ++ + S + + ++F+G Sbjct: 137 EKVSY---SNPTQTAATINNWVSEHTNGRLREIVTPDSLEGAVITLVNVIYFKGLWTYPF 193 Query: 284 QL--PGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGER-ATLLLIQPHC 340 V F+ + + G F + + A + +P + I P+ Sbjct: 194 PEVANNVKPFYGTRGKPTNAQYMEQNGQFYYDNSADLGAQILRLPYRGNKLAMYFILPNP 253 Query: 341 TSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEA 400 + +++V I L + + +TLP+ + S L + L + + + A Sbjct: 254 DNTVNQVLDRINSASLHQALWYMEENEVNVTLPKFKFDFSEQLNEPLQQVGIREIFSQNA 313 Query: 401 NLSNI-----GDTNPRVGEVLNSILLELKA-GEEEQPTTSVQQP---GSPEALDVTLSSP 451 +L + RV + + + G E T +Q G + P Sbjct: 314 SLPLLARGRGARDEVRVSRIFQKAGITINELGSEAYAATEIQLVNKFGGDGVQIFNANRP 373 Query: 452 FLFAIYEQDSGTLHFLGRVNNP 473 F+F I ++ GT+ F G++ NP Sbjct: 374 FIFFIEDETLGTMLFAGKIENP 395 >5NCU-A nrPDB Length = 336 Score = 198 bits (504), Expect = 3e-51, Method: Composition-based stats. Identities = 53/343 (15%), Positives = 122/343 (35%), Gaps = 26/343 (7%) Query: 102 NFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDC 161 N F + + + + +SP ++ L G+ TA +++T L + Sbjct: 12 NAFAFDLLQTTRK-HVTEANVFISPLSVSMALNMTLNGAAGVTADEMKTALRETGYTMED 70 Query: 162 TSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSF-VQSLALF 220 + H + AL V + ++ G +K F + + + Sbjct: 71 INEYS-HSLREALLKV------------DPSTTIGMANSIWYKQGELVKEPFILANRTHY 117 Query: 221 TPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMR 280 + +++D S+ L IN + T K+ L+ + ++ + V+F+G Sbjct: 118 DAEV--KAVDFSSPATLPA--INGWCAQKTNDKITKILDYIPGNAFMYLINAVYFKGIWV 173 Query: 281 GFSQLPGVH--EFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERA-TLLLIQ 337 + F + + V M++ F + +D + G +A +++++ Sbjct: 174 TQFKKSDTKRAPFRKADGTTQEVNMMAQKSTFGYTTDE--CCQYLEMDYGNKAFSMIVML 231 Query: 338 PHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNL-QDLLAEDKLPTLL 396 P+ V + I+ P + L +P+ + Y L + +L E + Sbjct: 232 PNEGQTTRDVIEQLDNKHWSMIIKGIRPTQVSLRMPRFKTECKYGLEKKILPEMGMNVPF 291 Query: 397 GAEANLSNIGDTNPRVGEVLNSILLEL-KAGEEEQPTTSVQQP 438 A+ I D + V++ +++ + G E T+V+ Sbjct: 292 TETADFPGITDAAIFISRVIHKTFVQVDEEGTEAAAVTAVEMV 334 >3STO-A nrPDB Length = 406 Score = 194 bits (494), Expect = 6e-50, Method: Composition-based stats. Identities = 60/370 (16%), Positives = 138/370 (37%), Gaps = 16/370 (4%) Query: 118 GASGAILSPPALFGTLVSF--YLGSLDPTASQLQTLLDVPVKEGDCTSRLDGHKVLAALR 175 G + P + TL G+ T Q+ + + S ++ + + Sbjct: 35 GGDNFLTCPLGILFTLGILLGSGGAQGRTGYQIGKTMRLKSTSSSWNSSEAQQEMKSLYQ 94 Query: 176 AVQGLLVTQGGSSSQTPL-LQSIMVGLFTAPGFRLKHSFVQSLALFTPALFPRSLDLSTD 234 + L ++ ++ + I G+F + ++ F +S+A + +D S Sbjct: 95 ELNNSLTSEKTFLNEKEENVVRISTGIFVEKTYEVERRFNESIAN-DSEGELKQVDFSNR 153 Query: 235 PVLATEKINRFIKAVTGWKMNLPL-EGVSTDSTLLFNTYVHFQGTMRGFSQL--PGVHEF 291 + IN ++ + + + + D+ ++ +F+ + + +F Sbjct: 154 TSATVD-INDWVDQQSNGLLEKFFTDDIPDDTAMILVNVFYFRDFWQSPFEPHYTRKEDF 212 Query: 292 WVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGE-RATLLLIQPHCTSDLDRVEAL 350 ++ ++V M++ G ++ F + PL R T +++ P L+ L Sbjct: 213 YISPDRQITVDMMTQEGVMKYGKFEDEGFEIVSKPLNNTRFTFVIVLPLEKWSLNGATEL 272 Query: 351 IF-RNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGA-EANLSNIG-D 407 + L +++N + L LP+ ++ + +L L + L +++LS I + Sbjct: 273 LNGNKVLSEYVKNLKETTVSLRLPKFTLKNTLDLVPTLKSIGVVDLFDPVKSDLSGITPN 332 Query: 408 TNPRVGEVLNSILLELKAGEEEQPTTSVQQP----GSPEALDVTLSSPFLFAIYEQDSGT 463 N V E + + +L+L E T + +D ++ PF+ IY+Q Sbjct: 333 PNLYVNEFIQTNVLKLNESGIEATTVTSPIFVPFSAIIPEVDFHVTHPFICFIYDQQLTM 392 Query: 464 LHFLGRVNNP 473 +V NP Sbjct: 393 PIMAAKVMNP 402 >2PEF-A nrPDB Length = 373 Score = 192 bits (488), Expect = 2e-49, Method: Composition-based stats. Identities = 68/386 (17%), Positives = 137/386 (35%), Gaps = 37/386 (9%) Query: 100 IANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEG 159 I N F + ++ + +++SP + L G+ + T +Q++ L Sbjct: 10 IYNTADFSI-ELFKNSIDDKENSLISPLSAMLALAMTANGADNETLAQMEKALGKD---- 64 Query: 160 DCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGL-FTAPGFRLKHSFVQSLA 218 S D +K L ++ +I + F F F+Q +A Sbjct: 65 --ISIEDLNKYLYTY---------MKKLPNEEKSKLTIANSIWFKENDFMPSKDFLQIIA 113 Query: 219 LFTPA-LFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQG 277 + A +F + D ST IN ++K+ T ++ L + + + V F Sbjct: 114 DYYKADIFKAAFDSSTVSD-----INNWVKSKTNGMIDKILNKIDPEDVMYLINAVAFDA 168 Query: 278 TMRGFSQLPGVHE--FWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGER-ATLL 334 + VHE F V ++ N + N P + + + Sbjct: 169 EWETVYEKASVHEDIFTDVYGNRQKVEFMNSEENLYI---EEENAVGFVKPYAKNHYSFV 225 Query: 335 LIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPT 394 I P ++ + + I+N +R +LP+ + + + + L + Sbjct: 226 AILPDENISVNEYIKTLTGQKFIDLIKNAKITLVRASLPKFKYEYTIKMNETLESLGMTD 285 Query: 395 LLGAE-ANLSNIGDT---NPRVGEVLNSILLELKA-GEEEQPTTSVQQPGSPEALDV--- 446 + A+ S +G + N + EVL+ + + G + TSV + ++ Sbjct: 286 AFLPDKADFSKLGKSDIGNLYISEVLHKTFISVDELGTKAGAVTSVDITAAGIPVNFKTV 345 Query: 447 TLSSPFLFAIYEQDSGTLHFLGRVNN 472 L+ PF+FAI + + F+G V + Sbjct: 346 KLNRPFIFAIIDNSTNLPIFIGTVLS 371 >6BJ5-B nrPDB Length = 315 Score = 156 bits (393), Expect = 3e-38, Method: Composition-based stats. Identities = 49/334 (14%), Positives = 105/334 (31%), Gaps = 49/334 (14%) Query: 112 LNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTSRLDGHKVL 171 + + + SP L L + + T ++ D L Sbjct: 23 FRYVYNESDNVVFSPYGLTSALSVLRIAAGGNTKREID-------VPESVVEDSDAFLAL 75 Query: 172 AALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLALFTPALFPRSLDL 231 LF L+ F A F+ + Sbjct: 76 RE---------------------------LFVDASVPLRPEFT---AEFSSRFNTSVQRV 105 Query: 232 STDPVLATEKINRFIKAVTGWKMNLPLE-GVSTDSTLLFNTYVHFQGTMRGFSQL--PGV 288 + + + IN ++K TG + L+ + D+ +L + V + + R Sbjct: 106 TFNSENVKDVINSYVKDKTGGDVPRVLDASLDRDTKMLLLSSVRMKTSWRHVFDPSFTTD 165 Query: 289 HEFWVDNSISVSVPMISGTGNFQH--WSDAQNNFSVTCVPLGERAT-LLLIQPHCTSDLD 345 F+ +++ V M++ + ++ +SVT +P R T +LL+ P DL Sbjct: 166 QPFY-SGNVTYKVRMMNKIDTLKTETFTLRNVGYSVTELPYKRRQTAMLLVVPD---DLG 221 Query: 346 RVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLG-AEANLSN 404 + + + + WI N ++ +P+ + +L+D L + + A+ Sbjct: 222 EIVRALDLSLVRFWIRNMRKDVCQVVMPKFSVESVLDLRDALQRLGVRDAFDPSRADFGQ 281 Query: 405 IG-DTNPRVGEVLNSILLELKAGEEEQPTTSVQQ 437 + V +VL + +E + + Sbjct: 282 ASPSNDLYVTKVLQTSKIEADERGTTASSDTAIT 315 >1SNG-A nrPDB Length = 370 Score = 146 bits (368), Expect = 2e-35, Method: Composition-based stats. Identities = 62/380 (16%), Positives = 119/380 (31%), Gaps = 43/380 (11%) Query: 104 VGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTS 163 +++ L EA I SP ++ L G+ + Sbjct: 17 FALHLHRRLAEAV-PDGEVIWSPYSVACALGVLAAGAR---------------------A 54 Query: 164 RLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLALFTPA 223 LL + + +P L S V L+ + ++ SF ++ P Sbjct: 55 TTRTELTTLLGTDPAPLLAALDRAVTDSPDLASRTV-LWVSADVPVRSSFRATMHD-RPD 112 Query: 224 LFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPL--EGVSTDSTLLFNTYVHFQGTMRG 281 R+ D T+P +N I T + L V+ D + + + Sbjct: 113 SDVRTADFRTNPEGVRATVNADIADATRGMIRELLPQGAVTPDLRAILTNALWAKARWTT 172 Query: 282 FSQ--LPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATLLLIQPH 339 + L F VP + T + + + + + + + ++ P Sbjct: 173 PFEAHLTRAGTFRTPRG-PKRVPFMHRTKTMPYATARG--WRMVTLHAHDELAVDVLLP- 228 Query: 340 CTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAE 399 A+ L ++ L LP+ E+ + L ++LAE + TL A Sbjct: 229 ---PGTNAAAVPTAPLLTALHRRSASTSVELALPRFELTQPHQLVEVLAEAGVRTLFTAS 285 Query: 400 ANLSNIGDTNPRVGEVLNSILLELKAG---EEEQPTTSVQQPGSPEA---LDVTLSSPFL 453 A+LS I V V++ L + + G+ + ++ PF Sbjct: 286 ADLSGISTVPLYVDTVIHQARLRVDERGAEGAAATAAMMLLAGAMPPRRTIRFSVDRPFH 345 Query: 454 FAIYEQDSGTLHFLGRVNNP 473 + G + FLG + +P Sbjct: 346 IVVR--RRGAILFLGSIADP 363 >1MTP-A nrPDB Length = 323 Score = 123 bits (309), Expect = 1e-28, Method: Composition-based stats. Identities = 54/326 (16%), Positives = 102/326 (31%), Gaps = 35/326 (10%) Query: 104 VGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTS 163 +++ L EA I SP ++ L G+ + Sbjct: 13 FALHLHRRLAEAV-PDGEVIWSPYSVACALGVLAAGAR---------------------A 50 Query: 164 RLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLALFTPA 223 LL + + +P L S V L+ + ++ SF ++ P Sbjct: 51 TTRTELTTLLGTDPAPLLAALDRAVTDSPDLASRTV-LWVSADVPVRSSFRATMHD-RPD 108 Query: 224 LFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPL--EGVSTDSTLLFNTYVHFQGTMRG 281 R+ D T+P +N I T + L V+ D + + + Sbjct: 109 SDVRTADFRTNPEGVRATVNADIADATRGMIRELLPQGAVTPDLRAILTNALWAKARWTT 168 Query: 282 FSQ--LPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATLLLIQPH 339 + L F VP + T + + + + + + + ++ P Sbjct: 169 PFEAHLTREGTFRTPRG-PKRVPFMHRTKTMPYATARG--WRMVTLHAHDELAVDVLLP- 224 Query: 340 CTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAE 399 A+ L ++ L LP+ E+ + L ++LAE + TL A Sbjct: 225 ---PGTNAAAVPTAPLLTALHRRSASTSVELALPRFELTQPHQLVEVLAEAGVRTLFTAS 281 Query: 400 ANLSNIGDTNPRVGEVLNSILLELKA 425 A+LS I V V++ L + Sbjct: 282 ADLSGISTVPLYVDTVIHQARLRVDE 307 >5C98-A nrPDB Length = 382 Score = 101 bits (252), Expect = 6e-22, Method: Composition-based stats. Identities = 58/396 (14%), Positives = 116/396 (29%), Gaps = 58/396 (14%) Query: 97 VAMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPV 156 + N +K + +SP + L FY + Q +P Sbjct: 17 IVAANNKFTLEYFKACYDEKC---NCAVSPYHVRLALSMFYPLAGAAVQEDFQVAFGLPE 73 Query: 157 KEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQS 216 + ++ L Q L + + RL F + Sbjct: 74 DVHAAIEQQQ--RLAQQLHDGQHL---------------KALSFVLVEETLRLDSEFERL 116 Query: 217 L-ALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEG-----VSTDSTLLFN 270 F + P +DL+ D A + + +A T + + + L+ Sbjct: 117 FHRTFQTTVEP--VDLTDDIPSALAVNSFYQRANTE--IEDFIGEGDVFSLPPCHKLML- 171 Query: 271 TYVHFQGT-------MRGFSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVT 323 F G +R + F N+ + V + T + + V Sbjct: 172 ----FSGVSVLTPLAIRFNPADTALELFQFINAPTQRVSTMHTTAFVRRCLHNELRCKVV 227 Query: 324 CVPL--GERATLLLIQPHCTSDLDRVEALIFRNDLLTWIENPPPRAIRLTLPQLEIRGSY 381 +P ++L++ P+ ++L ++ I L E L LP+ +R Sbjct: 228 DMPFDAASGLSMLVLLPYDGTELRQIVNSITPAHLAQIDERLQSCWTDLKLPKFFVREKT 287 Query: 382 NLQDLLAEDKLPTLLGAEANL-----SNIGDTNPRVGEVLNSILLELKAGEEEQPTTSVQ 436 + + L + + + +L S N G + + L E + Sbjct: 288 DPKQTLGKLGYGGVFEID-DLHVFHDSGRTRLN---GFIQHCYLA-----VSESGSGIPA 338 Query: 437 QPGSPEALDVTLSSPFLFAIYEQDSGTLHFLGRVNN 472 P +P + + PF+F I G + +G + Sbjct: 339 PPDTPSEFEFHANRPFMFLIRRTMDGNVLQVGNFSK 374 >4R9I-A nrPDB Length = 378 Score = 73.6 bits (179), Expect = 2e-13, Method: Composition-based stats. Identities = 62/372 (16%), Positives = 129/372 (34%), Gaps = 47/372 (12%) Query: 118 GASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAV 177 + L L L S + T ++L L++ ++ V+ +AV Sbjct: 37 PERNQFSTAFPLLFMLSELSLNSKEDTTAELYKNLNLRSEDE----------VVNVNQAV 86 Query: 178 QGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQSLALFTPALFPRSLDLSTDPVL 237 L T+ T +L + +T +F+Q+ A +++D S D Sbjct: 87 NTNLNTKNEVYQSTLILNA-----YTDIDSPFSETFIQNFAKVFNGTV-KNIDYSND--- 137 Query: 238 ATEKINRFIKAVTGWKMNLPLEG--VSTDSTLLFNTY--VHFQGTMRGFSQLPGVHE--- 290 A I +++ +G + + L+ ++ D+ ++ Y ++F S ++ Sbjct: 138 AVATIRDSLQSDSGNDIEIALKDGDINKDTGIILTAYTNIYF--PWGEASDSYRPYKQID 195 Query: 291 --FWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATLLLIQP-HCTSDLDRV 347 F + + G ++ V L T++L + +DL Sbjct: 196 ISFTALDGTQSNKQAWYSEGAGKYAEIENLGIKVFQFSLKPGLTVVLGTSLNDNNDLSGA 255 Query: 348 EALI-FRNDLLTWIENPPPRAIRLTLP-QLEIRGSYNLQDLLAEDKL-PTLLGAEANLSN 404 + L + + ++L +P +L +R S + + L L N Sbjct: 256 FNKLRDPATLAYILTQTESKYLKLAVPIELTMRDSRDYIPEVKRAGLLTELFEK--NFDG 313 Query: 405 IG----DTNPRVGEVLNSILLELKAGEEEQPTTSVQQPGSPEALDVTLSSPFLFAIYEQD 460 + + + +L+ LE + EEQ + V +P D P+ F + +Q Sbjct: 314 FDTVYDNKSGYISYMLSHTRLEFEQPTEEQAASVVAEP------DFIFDKPYFFLVLDQF 367 Query: 461 SGTLHFLGRVNN 472 T F+G + N Sbjct: 368 -NTPAFIGLITN 378 >2P6F-A nrPDB Length = 455 Score = 33.9 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 17/104 (16%), Positives = 35/104 (33%), Gaps = 4/104 (3%) Query: 156 VKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGFRLKHSFVQ 215 + E D T DGH + + L + ++ L + + +F F+ S + Sbjct: 229 LYEVDFTGLPDGHTEEDMIA--ENALPAKTKTAGLRKLKKEDIDQVF--ELFKRYQSRFE 284 Query: 216 SLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLE 259 + +FT F + L + I ++ K+ Sbjct: 285 LIQIFTKEEFEHNFIGEESLPLDKQVIFSYVVEQPDGKITDFFS 328 >4GWP-B nrPDB Length = 687 Score = 32.0 bits (71), Expect = 0.66, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 25/56 (44%) Query: 35 LYHNKSTCAQLENPSVETLPESTFEPVPIQAKTSPVNEKTLHDQLVLAAEKLEDED 90 L N T A NP+ ++ EPVP A + + + D+L +K D++ Sbjct: 21 LDPNLITLALSSNPNSSLHSPTSDEPVPESAGKADTSIRLEGDELENKTKKDNDKN 76 >6GCS-K nrPDB Length = 210 Score = 30.4 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 21/50 (42%) Query: 26 RVYIHPFHLLYHNKSTCAQLENPSVETLPESTFEPVPIQAKTSPVNEKTL 75 R + P ++ ++ A P V + T P+P Q K + + TL Sbjct: 12 RPTLVPATVIPQTRAYSAPAGTPRVSSSSMPTDFPLPSQQKPNSAVDYTL 61 >4X04-A nrPDB Length = 323 Score = 29.7 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 25/109 (22%), Positives = 40/109 (36%), Gaps = 16/109 (14%) Query: 360 IENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLSNIGDTNPRVGEVLNSI 419 +NP + L ++ ++GS D L + AN +G V EV + + Sbjct: 153 TKNPVEKPEDLHGMKIRVQGSPVALDTLKDMG--------ANSVAMG-----VSEVFSGM 199 Query: 420 LLELKAGEEEQPTTSVQQPGSPEALDVTLSSPFL---FAIYEQDSGTLH 465 + G E P T V P A + TLS F+ +Y + Sbjct: 200 QTGVIDGAENNPPTFVAHNYMPVAKNYTLSGHFITPEMLLYSKVKWDKL 248 >3RG1-A nrPDB Length = 612 Score = 29.3 bits (64), Expect = 3.9, Method: Composition-based stats. Identities = 22/118 (18%), Positives = 38/118 (32%), Gaps = 12/118 (10%) Query: 98 AMIANFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSL--------DPTASQLQ 149 + G + K L +G S P L S +LGS + +Q Sbjct: 95 MAETSLTGPKFLKHLFLTQTGISNLEFIPVHNLENLESLHLGSNHISSINLPENFPTQNL 154 Query: 150 TLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIMVGLFTAPGF 207 +LD SR D + +L L + G+ + + + +F + F Sbjct: 155 KVLDFQNNAIHYISRKDTN----SLEQATNLSLNFNGNDIKGIEPGAFISKIFQSLKF 208 >5LN3-Z nrPDB Length = 908 Score = 29.3 bits (64), Expect = 3.9, Method: Composition-based stats. Identities = 7/38 (18%), Positives = 17/38 (44%) Query: 61 VPIQAKTSPVNEKTLHDQLVLAAEKLEDEDRKRAAQVA 98 P+Q + SP D+ E+ + D+ + +++ Sbjct: 9 APVQPQQSPAAAPGGTDEKPSGKERRDAGDKDKEQELS 46 >6BWI-A nrPDB Length = 977 Score = 28.9 bits (63), Expect = 5.5, Method: Composition-based stats. Identities = 10/42 (23%), Positives = 16/42 (38%) Query: 26 RVYIHPFHLLYHNKSTCAQLENPSVETLPESTFEPVPIQAKT 67 R Y+ F + A +E+ + + P P QA T Sbjct: 770 RPYLQIFGQIPQEDMDVALMEHSNCSSEPGFWAHPPGAQAGT 811 >4PSX-A nrPDB Length = 320 Score = 28.1 bits (61), Expect = 7.6, Method: Composition-based stats. Identities = 11/113 (9%), Positives = 37/113 (32%), Gaps = 5/113 (4%) Query: 293 VDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATLLLIQPHCTSDLDRVEALIF 352 ++ + ++ + + + + + + LI P + + ++ Sbjct: 180 LNKKTKELIGFVTTYKYWHYLGAKSFDEDIDK-KFRAKISQFLIFPPYQNKGHG--SCLY 236 Query: 353 RNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDL--LAEDKLPTLLGAEANLS 403 + +W+E+ I + P + D+ L + + ++LS Sbjct: 237 EAIIQSWLEDKSITEITVEDPNEAFDDLRDRNDIQRLRKLGYDAVFQKHSDLS 289 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.131 0.347 Lambda K H 0.267 0.0405 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,685,863 Number of Sequences: 36641 Number of extensions: 616424 Number of successful extensions: 2251 Number of sequences better than 10.0: 71 Number of HSP's better than 10.0 without gapping: 100 Number of HSP's successfully gapped in prelim test: 26 Number of HSP's that attempted gapping in prelim test: 1750 Number of HSP's gapped (non-prelim): 141 length of query: 477 length of database: 10,336,785 effective HSP length: 101 effective length of query: 376 effective length of database: 6,636,044 effective search space: 2495152544 effective search space used: 2495152544 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (28.1 bits)