BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P11310 (421 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2A1T-A nrPDB 874 0.0 3MDE-A nrPDB 731 0.0 1UKW-A nrPDB 374 e-104 3PFD-A nrPDB 290 1e-78 1JQI-A nrPDB 279 1e-75 4L1F-A nrPDB 275 2e-74 5LNX-A nrPDB 275 4e-74 5OL2-C nrPDB 273 7e-74 2VIG-A nrPDB 269 1e-72 4U83-A nrPDB 266 2e-71 4N5F-A nrPDB 259 1e-69 1BUC-A nrPDB 255 3e-68 6FAH-C nrPDB 251 4e-67 4KTO-A nrPDB 249 1e-66 2DVL-A nrPDB 249 2e-66 2JIF-A nrPDB 247 8e-66 2Z1Q-A nrPDB 246 1e-65 4M9A-A nrPDB 243 8e-65 1RX0-A nrPDB 240 1e-63 3NF4-A nrPDB 239 2e-63 4O5M-A nrPDB 238 5e-63 4IV6-A nrPDB 236 2e-62 1IVH-A nrPDB 231 3e-61 2CX9-A nrPDB 230 7e-61 3MPI-A nrPDB 229 2e-60 3OWA-A nrPDB 217 8e-57 6ES9-A nrPDB 215 3e-56 5IDU-A nrPDB 211 4e-55 2PG0-A nrPDB 210 9e-55 3R7K-A nrPDB 206 2e-53 5AHS-A nrPDB 202 2e-52 5JSC-A nrPDB 195 2e-50 4IRN-A nrPDB 192 2e-49 3P4T-A nrPDB 187 1e-47 3B96-A nrPDB 179 1e-45 2EBA-A nrPDB 179 2e-45 3GNC-A nrPDB 155 3e-38 3SF6-A nrPDB 152 3e-37 6CY8-B nrPDB 150 7e-37 4W9U-A nrPDB 150 1e-36 4HR3-A nrPDB 141 6e-34 2IX5-A nrPDB 141 6e-34 1SIR-A nrPDB 140 8e-34 5ZW7-A nrPDB 140 1e-33 3SWO-A nrPDB 129 3e-30 1R2J-A nrPDB 129 3e-30 2WBI-A nrPDB 124 1e-28 3MKH-A nrPDB 123 2e-28 4X28-A nrPDB 104 8e-23 4RM7-A nrPDB 104 8e-23 2C12-A nrPDB 100 2e-21 5GJ7-A nrPDB 75 6e-14 5EZ3-A nrPDB 74 1e-13 3U33-A nrPDB 70 1e-12 3M9V-A nrPDB 69 5e-12 4XVX-A nrPDB 65 4e-11 4Y9J-A nrPDB 59 3e-09 4X28-D nrPDB 58 6e-09 3MXL-A nrPDB 58 9e-09 1W07-A nrPDB 56 3e-08 2FON-A nrPDB 54 1e-07 4ZYJ-A nrPDB 54 1e-07 5YS9-A nrPDB 53 2e-07 5K3G-A nrPDB 47 2e-05 5Y9D-A nrPDB 44 9e-05 5XDD-A nrPDB 39 0.004 1IS2-A nrPDB 37 0.022 4D1J-A nrPDB 33 0.24 2R60-A nrPDB 32 0.45 6NCL-d0 nrPDB 32 0.67 5K3J-A nrPDB 32 0.69 2RFQ-A nrPDB 30 2.3 4ZNZ-A nrPDB 29 3.2 5W5B-A nrPDB 29 4.6 4E20-A nrPDB 28 6.5 >2A1T-A nrPDB Length = 421 Score = 874 bits (2259), Expect = 0.0, Method: Compositional matrix adjust. Identities = 421/421 (100%), Positives = 421/421 (100%) Query: 1 MAAGFGRCCRVLRSISRFHWRSQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEI 60 MAAGFGRCCRVLRSISRFHWRSQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEI Sbjct: 1 MAAGFGRCCRVLRSISRFHWRSQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEI 60 Query: 61 IPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQ 120 IPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQ Sbjct: 61 IPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQ 120 Query: 121 TAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKG 180 TAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKG Sbjct: 121 TAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKG 180 Query: 181 DEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNM 240 DEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNM Sbjct: 181 DEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNM 240 Query: 241 GQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEAT 300 GQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEAT Sbjct: 241 GQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEAT 300 Query: 301 KYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAF 360 KYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAF Sbjct: 301 KYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAF 360 Query: 361 AGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDKYK 420 AGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDKYK Sbjct: 361 AGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDKYK 420 Query: 421 N 421 N Sbjct: 421 N 421 >3MDE-A nrPDB Length = 385 Score = 731 bits (1887), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/385 (89%), Positives = 370/385 (96%) Query: 36 GFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENC 95 GFSFE TEQQKEFQATARKFAREEIIPVAAEYD+TGEYPVPL++RAWELGLMNTHIPE+ Sbjct: 1 GFSFELTEQQKEFQATARKFAREEIIPVAAEYDRTGEYPVPLLKRAWELGLMNTHIPESF 60 Query: 96 GGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLM 155 GGLGLG D+CLI+EELAYGCTGVQTAIE N+LGQ+P+II GN QQ+KKYLGRMTEEPLM Sbjct: 61 GGLGLGIIDSCLITEELAYGCTGVQTAIEANTLGQVPLIIGGNYQQQKKYLGRMTEEPLM 120 Query: 156 CAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA 215 CAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA Sbjct: 121 CAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA 180 Query: 216 NKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMG 275 +KAFTGFIVEADTPG+QIGRKE+NMGQRCSDTRGIVFEDV+VPKENVL G+GAGFK+AMG Sbjct: 181 SKAFTGFIVEADTPGVQIGRKEINMGQRCSDTRGIVFEDVRVPKENVLTGEGAGFKIAMG 240 Query: 276 AFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARM 335 FDKTRP VAAGAVGLAQRALDEATKYALERKTFGKLL EHQ ISF+LA+MAMKVELAR+ Sbjct: 241 TFDKTRPPVAAGAVGLAQRALDEATKYALERKTFGKLLAEHQGISFLLADMAMKVELARL 300 Query: 336 SYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAK 395 SYQRAAWE+DSGRRNTYYASIAKA+A DIANQLATDAVQ+ GGNGFNTEYPVEKLMRDAK Sbjct: 301 SYQRAAWEIDSGRRNTYYASIAKAYAADIANQLATDAVQVFGGNGFNTEYPVEKLMRDAK 360 Query: 396 IYQIYEGTSQIQRLIVAREHIDKYK 420 IYQIYEGT+QIQR+I+AREHI +YK Sbjct: 361 IYQIYEGTAQIQRIIIAREHIGRYK 385 >1UKW-A nrPDB Length = 379 Score = 374 bits (960), Expect = e-104, Method: Compositional matrix adjust. Identities = 185/380 (48%), Positives = 259/380 (68%), Gaps = 4/380 (1%) Query: 37 FSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCG 96 F TE+Q++ QA AR+FA+E I+PVA EYD+ E P P+I + E+GL+N IPE G Sbjct: 1 IDFSLTEEQRQLQALARRFAKEVILPVAQEYDEKEEVPWPVIEKLHEVGLLNAIIPEEYG 60 Query: 97 GLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMC 156 G+GL D ++ EELAY C G+ T + LG P+++AG ++QK+++L +TE+P + Sbjct: 61 GMGLKMLDEVIVGEELAYACMGIYTIPMASDLGITPVLLAGTEEQKERFLRPLTEKPALA 120 Query: 157 AYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPAN 216 A+ ++EPG GSD A +KT+A ++GD Y++NG KMWI+NGG+A W + A +P+ + + Sbjct: 121 AFALSEPGNGSDAAALKTRAIRQGDHYVLNGTKMWISNGGEAEWVVVFATVNPELR---H 177 Query: 217 KAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGA 276 K +VE TPG + + MGQR S T +VFEDVKVP EN L +G GFK+AM Sbjct: 178 KGVVALVVERGTPGFKAIKIHGKMGQRASGTYELVFEDVKVPVENRLGEEGEGFKIAMQT 237 Query: 277 FDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMS 336 +KTR VAAG+VG+A+RALDEA KYA ER+ FG+ + QAI F L +M + +E ARM Sbjct: 238 LNKTRIPVAAGSVGVARRALDEARKYAKEREAFGEPIANFQAIQFKLVDMLIGIETARMY 297 Query: 337 YQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKI 396 AAW D G + + ++IAKA+A +IA + A A+QI GG G+ E+PVEKL+RD K+ Sbjct: 298 TYYAAWLADQGLPHAHASAIAKAYASEIAFEAANQAIQIHGGYGYVREFPVEKLLRDVKL 357 Query: 397 YQIYEGTSQIQRLIVAREHI 416 QIYEGT++IQRLI+AR HI Sbjct: 358 NQIYEGTNEIQRLIIAR-HI 376 >3PFD-A nrPDB Length = 393 Score = 290 bits (741), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 150/376 (39%), Positives = 222/376 (59%), Gaps = 4/376 (1%) Query: 39 FEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGL 98 F+ E+ + R A +EI P AAE D+ +P + G H+PE GG Sbjct: 17 FQLPEEHIALREAIRALAEKEIAPYAAEVDEKARFPEEALAALNSSGFSAIHVPEEYGGQ 76 Query: 99 GLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAY 158 G + C++ EE+A N LG M +I+ G+++ KK+ L + M +Y Sbjct: 77 GADSVATCIVIEEVARVDCSASLIPAVNKLGTMGLILRGSEELKKQVLPAVASGEAMASY 136 Query: 159 CVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKA 218 ++E AGSD A ++T+A GD++I+NG K WITNGGK+ WY ++A +DPD A Sbjct: 137 ALSEREAGSDAASMRTRAVADGDDWILNGSKCWITNGGKSTWYTVMAVTDPDKGA---NG 193 Query: 219 FTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFD 278 + F+V D G +G KE +G + S T + FE+ ++P + ++ G GFK A+ D Sbjct: 194 ISAFMVHKDDEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRIIGEPGTGFKTALATLD 253 Query: 279 KTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQ 338 TRP + A AVG+AQ ALD A Y ERK FG+ + ++Q + FMLA+MAMK+E AR+ Sbjct: 254 HTRPTIGAQAVGIAQGALDAAIAYTKERKQFGRPVSDNQGVQFMLADMAMKIEAARLMVY 313 Query: 339 RAAWEVDSGRRNTYYASIA-KAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIY 397 AA + G + + S A K FA D+A ++ TDAVQ+ GG G+ ++PVE++MRDAKI Sbjct: 314 SAAARAERGEGDLGFISAASKCFASDVAMEVTTDAVQLFGGYGYTQDFPVERMMRDAKIT 373 Query: 398 QIYEGTSQIQRLIVAR 413 QIYEGT+QIQR++++R Sbjct: 374 QIYEGTNQIQRVVMSR 389 >1JQI-A nrPDB Length = 388 Score = 279 bits (714), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 151/386 (39%), Positives = 231/386 (59%), Gaps = 6/386 (1%) Query: 38 SFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGG 97 S E E + + T R FA +E++P+AA+ DK +P +++ ELGL+ +PE G Sbjct: 7 SVELPETHQMLRQTCRDFAEKELVPIAAQLDKEHLFPTSQVKKMGELGLLAMDVPEELSG 66 Query: 98 LGLGTFDACLISEELAYGC--TGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLM 155 GL + EE++ GC TGV ++ NSL PI+ G+ QQK++++ T + Sbjct: 67 AGLDYLAYSIALEEISRGCASTGVIMSVN-NSLYLGPILKFGSSQQKQQWITPFTNGDKI 125 Query: 156 CAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA 215 + ++EPG GSD T A ++GD +++NG K WITN +A+ + A +D ++ Sbjct: 126 GCFALSEPGNGSDAGAASTTAREEGDSWVLNGTKAWITNSWEASATVVFASTD---RSRQ 182 Query: 216 NKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMG 275 NK + F+V TPG+ +G+KE +G R S T ++FED ++PKEN+L G GFK+AM Sbjct: 183 NKGISAFLVPMPTPGLTLGKKEDKLGIRASSTANLIFEDCRIPKENLLGEPGMGFKIAMQ 242 Query: 276 AFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARM 335 D R +A+ A+G+AQ +LD A KYA R FG L + Q I F LA+MA+ +E AR+ Sbjct: 243 TLDMGRIGIASQALGIAQASLDCAVKYAENRHAFGAPLTKLQNIQFKLADMALALESARL 302 Query: 336 SYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAK 395 RAA D+ + T +++AK A + A ++ A+QILGG G+ TE P E+ RDA+ Sbjct: 303 LTWRAAMLKDNKKPFTKESAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERYYRDAR 362 Query: 396 IYQIYEGTSQIQRLIVAREHIDKYKN 421 I +IYEGTS+IQRL++A + Y++ Sbjct: 363 ITEIYEGTSEIQRLVIAGHLLRSYRS 388 >4L1F-A nrPDB Length = 383 Score = 275 bits (703), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 154/376 (40%), Positives = 223/376 (59%), Gaps = 4/376 (1%) Query: 39 FEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGL 98 F TE Q+ + A +FA + + P E DK + LI + E G PE GG+ Sbjct: 3 FNLTEDQQMIKDMAAEFAEKFLAPTVEERDKAHIWDRKLIDKMGEAGFCGICFPEEYGGM 62 Query: 99 GLGTFDACLISEELAYGCTGVQTAIEGN-SLGQMPIIIAGNDQQKKKYLGRMTEEPLMCA 157 GL L EEL+ G + N SL PI + G ++QK+KYL + E + A Sbjct: 63 GLDVLSYILAVEELSKVDDGTGITLSANVSLCATPIYMFGTEEQKQKYLAPIAEGTHVGA 122 Query: 158 YCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANK 217 + +TEP AG+D + +T A KGD+YI+NG K++ITNG +A+ Y + A +D K+ Sbjct: 123 FGLTEPSAGTDASAQQTTAVLKGDKYILNGSKIFITNGKEADTYVVFAMTD---KSQGVH 179 Query: 218 AFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAF 277 + FI+E PG + G+ E MG S T ++FED +VPKEN+L +G GFK+AM Sbjct: 180 GISAFILEKGMPGFRFGKIEDKMGGHTSITAELIFEDCEVPKENLLGKEGEGFKIAMETL 239 Query: 278 DKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSY 337 D R VAA A+G+A+ AL A KY+ ER+ FG+ + + QA+ FM+A+MA K+E AR Sbjct: 240 DGGRIGVAAQALGIAEGALAAAVKYSKEREQFGRSISKFQALQFMMADMATKIEAARYLV 299 Query: 338 QRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIY 397 AA + G+ + A++AK FA D+A ++ TDAVQI GG G+ +YP E+ MR+AKI Sbjct: 300 YHAAMLKNEGKPYSEAAAMAKCFASDVAMEVTTDAVQIFGGYGYTVDYPAERYMRNAKIT 359 Query: 398 QIYEGTSQIQRLIVAR 413 QIYEGT+Q+ R++ +R Sbjct: 360 QIYEGTNQVMRIVTSR 375 >5LNX-A nrPDB Length = 379 Score = 275 bits (702), Expect = 4e-74, Method: Compositional matrix adjust. Identities = 151/377 (40%), Positives = 224/377 (59%), Gaps = 6/377 (1%) Query: 39 FEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGL 98 T++Q + R FAR+EI P A +KT E+P LI++ + GLM +PE GG Sbjct: 1 MHVTQEQVMMRKMVRDFARKEIAPAAEIMEKTDEFPFQLIKKMGKHGLMGIPVPEQYGGA 60 Query: 99 GLGTFDACLISEELA--YGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMC 156 G L E++ GV ++ S+G PI+ GN++QK KY+ + + Sbjct: 61 GADVVSYILAIHEISRISAAVGVILSVH-TSVGTNPILYFGNEEQKMKYIPNLASGDHLG 119 Query: 157 AYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPAN 216 A+ +TEP +GSD ++T A KK +Y++NG K++ITNGG A+ Y A + PD Sbjct: 120 AFALTEPHSGSDAGSLRTTAIKKNGKYLLNGSKIFITNGGAADIYITFALTAPDQ---GR 176 Query: 217 KAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGA 276 + FIVE +TPG +G+KE +G S+T ++F++ +VP+ N+L +G GF +AM Sbjct: 177 HGISAFIVEKNTPGFTVGKKERKLGLYGSNTTELIFDNAEVPEANLLGKEGDGFHIAMAN 236 Query: 277 FDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMS 336 + R +AA A+G+A+ AL+ A YA +R FG+ + +Q ISF LA+MA + E AR Sbjct: 237 LNVGRIGIAAQALGIAEAALEHAVDYAKQRVQFGRPIAANQGISFKLADMATRAEAARHL 296 Query: 337 YQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKI 396 AA + G AS+AK FA D A + A DAVQI GG G+ +YPVE+L+RDAK+ Sbjct: 297 VYHAADLHNRGLNCGKEASMAKQFASDAAVKAALDAVQIYGGYGYMKDYPVERLLRDAKV 356 Query: 397 YQIYEGTSQIQRLIVAR 413 QIYEGT++IQRLI+++ Sbjct: 357 TQIYEGTNEIQRLIISK 373 >5OL2-C nrPDB Length = 378 Score = 273 bits (699), Expect = 7e-74, Method: Compositional matrix adjust. Identities = 153/360 (42%), Positives = 218/360 (60%), Gaps = 6/360 (1%) Query: 55 FAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAY 114 FA E+ P+A E D+ +P + + + G+M P+ GG G T + EEL+ Sbjct: 18 FAENEVKPLATELDEEERFPYETVEKMAKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSR 77 Query: 115 GC--TGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGI 172 C TGV + SLG PI GN++QK+K+L + + A+ +TEP AG+D +G Sbjct: 78 VCGTTGVILSAH-TSLGSWPIYQYGNEEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQ 136 Query: 173 KTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQ 232 +T A GDEYI+NG K++ITN + Y ++A +D K+ NK + FIVE TPG Sbjct: 137 QTTAVLDGDEYILNGSKIFITNAIAGDIYVVMAMTD---KSKGNKGISAFIVEKGTPGFS 193 Query: 233 IGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLA 292 G KE MG R S T ++FED ++PKEN+L +G GFK+AM D R +AA A+GLA Sbjct: 194 FGVKEKKMGIRGSATSELIFEDCRIPKENLLGKEGQGFKIAMSTLDGGRIGIAAQALGLA 253 Query: 293 QRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTY 352 Q ALDE KY ER FG+ L + Q F LA+M +KV+ AR +AA D G+ Sbjct: 254 QGALDETVKYVKERVQFGRPLSKFQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGV 313 Query: 353 YASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVA 412 A++AK FA + A ++ T AVQ+ GG G+ +YPVE++MRDAKI +IYEGTS++QR++++ Sbjct: 314 EAAMAKLFAAETAMEVTTKAVQLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVIS 373 >2VIG-A nrPDB Length = 391 Score = 269 bits (688), Expect = 1e-72, Method: Compositional matrix adjust. Identities = 149/386 (38%), Positives = 226/386 (58%), Gaps = 6/386 (1%) Query: 38 SFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGG 97 S E E + T R FA +E+ P+AA+ DK +P +++ LGL+ +PE GG Sbjct: 3 SVELPETHQMLLQTCRDFAEKELFPIAAQVDKEHLFPAAQVKKMGGLGLLAMDVPEELGG 62 Query: 98 LGLGTFDACLISEELAYGC--TGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLM 155 GL + EE++ GC TGV ++ NSL PI+ G+ +QK+ ++ T + Sbjct: 63 AGLDYLAYAIAMEEISRGCASTGVIMSVN-NSLYLGPILKFGSKEQKQAWVTPFTSGDKI 121 Query: 156 CAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA 215 + ++EPG GSD T A +GD +++NG K WITN +A+ + A +D +A Sbjct: 122 GCFALSEPGNGSDAGAASTTARAEGDSWVLNGTKAWITNAWEASAAVVFASTD---RALQ 178 Query: 216 NKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMG 275 NK+ + F+V TPG+ +G+KE +G R S T ++FED ++PK+++L G GFK+AM Sbjct: 179 NKSISAFLVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILGEPGMGFKIAMQ 238 Query: 276 AFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARM 335 D R +A+ A+G+AQ ALD A YA R FG L + Q I F LA+MA+ +E AR+ Sbjct: 239 TLDMGRIGIASQALGIAQTALDCAVNYAENRMAFGAPLTKLQVIQFKLADMALALESARL 298 Query: 336 SYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAK 395 RAA D+ + A++AK A + A ++ A+QILGG G+ TE P E+ RDA+ Sbjct: 299 LTWRAAMLKDNKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERHYRDAR 358 Query: 396 IYQIYEGTSQIQRLIVAREHIDKYKN 421 I +IYEGTS+IQRL++A + Y++ Sbjct: 359 ITEIYEGTSEIQRLVIAGHLLRSYRS 384 >4U83-A nrPDB Length = 382 Score = 266 bits (679), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 146/374 (39%), Positives = 220/374 (58%), Gaps = 4/374 (1%) Query: 41 FTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGL 100 T+ Q++ + AR FA+E + P AA D+ +P + LG + PE GG L Sbjct: 10 LTDTQEQIREAARDFAQERLAPGAAARDREHAFPRAELTEMGALGFLGMLAPEEWGGSDL 69 Query: 101 GTFDACLISEELAYGCTGVQTAIE-GNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYC 159 L EE+A G T + +S+G MPI+ G + QK+++L +M + + Sbjct: 70 DMVAYALALEEIAAGDGACSTIVSVHSSVGCMPILRFGTEDQKRRFLPKMACGEWIGGFA 129 Query: 160 VTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAF 219 +TEP AGSD + +KT+A GD Y+I+G K +IT+G N + A +DP A K Sbjct: 130 LTEPQAGSDASALKTRARLDGDHYVIDGSKQFITSGKNGNVVIVFAVTDP---AAGKKGI 186 Query: 220 TGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDK 279 + FIV DTPG ++ E +GQ SDT + F +++VP EN L +G G+K+A+ + Sbjct: 187 SAFIVPTDTPGYEVMSVEHKLGQHSSDTCALGFTNMRVPVENRLGAEGEGYKIALANLEG 246 Query: 280 TRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQR 339 R +AA AVG+A+ A + A YA ER TFGK ++EHQA++F LA+MA ++E AR Sbjct: 247 GRIGIAAQAVGMARAAFEAARDYARERITFGKPIIEHQAVAFRLADMATRIETARQMVLH 306 Query: 340 AAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQI 399 AA ++G+ AS+AK A ++A Q+ + A+QI GG G+ +YPVE++ RD ++ QI Sbjct: 307 AAALREAGKPCLTEASMAKLVASEMAEQVCSAAIQIHGGYGYLADYPVERIYRDVRVCQI 366 Query: 400 YEGTSQIQRLIVAR 413 YEGTS +QRL++AR Sbjct: 367 YEGTSDVQRLVIAR 380 >4N5F-A nrPDB Length = 385 Score = 259 bits (663), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 143/375 (38%), Positives = 222/375 (59%), Gaps = 4/375 (1%) Query: 41 FTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGL 100 +TE Q+ + AR FA E + P AA++D P ++ + ELGL+ +P+ GG Sbjct: 13 YTEDQRMIRDAARAFATEMLAPNAAQWDHDAHLPDAIVAQLGELGLLGMIVPQELGGSYT 72 Query: 101 GTFDACLISEELAYGCTGVQTAIE-GNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYC 159 L EE+A G T + NS+G PI+ G QK ++L M ++ A+C Sbjct: 73 DYVAYALAMEEVAAGDAACATMMSVHNSVGCGPILGFGTPAQKDRWLADMAAGRVIGAFC 132 Query: 160 VTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAF 219 +TEP AGS+ ++T+AE + ++++NG K ++TNG +A + A +DP+ + Sbjct: 133 LTEPHAGSEANNLRTRAELRDGQWVLNGAKQFVTNGQRAGVAIVFAMTDPEA---GKRGI 189 Query: 220 TGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDK 279 + F+V DTPG +G+ E MG R SDT I FE+ +P++N+L G G K+A+ + Sbjct: 190 SAFLVPTDTPGFIVGKPEKKMGIRASDTCPITFENCAIPEDNLLGNRGEGLKIALSNLEG 249 Query: 280 TRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQR 339 R +AA A+G+A+ A D+A +YA ER FGK + EHQAI LA+MA+++ AR+ Sbjct: 250 GRIGIAAQALGIARAAFDKARRYAGERVQFGKPIAEHQAIQQKLADMAVQINAARLLVHH 309 Query: 340 AAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQI 399 AA +G AS AK FA ++A ++ +DA+QI GG G+ +Y VE+ RDA+I QI Sbjct: 310 AAKLRTAGLPCLSEASQAKLFASEMAERVCSDAIQIHGGYGYLVDYEVERHYRDARITQI 369 Query: 400 YEGTSQIQRLIVARE 414 YEGTS++QR+++AR+ Sbjct: 370 YEGTSEVQRMVIARQ 384 >1BUC-A nrPDB Length = 383 Score = 255 bits (651), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 156/377 (41%), Positives = 217/377 (57%), Gaps = 8/377 (2%) Query: 39 FEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPEN---C 95 F T+ Q++F A F +++ P E D G Y LI LG+ + E Sbjct: 3 FNLTDIQQDFLKLAHDFGEKKLAPTVTERDHKGIYDKELIDELLSLGITGAYFEEKYGGS 62 Query: 96 GGLGLGTFDACLISEELAYGCTGVQTAIEGN-SLGQMPIIIAGNDQQKKKYLGRMTEEPL 154 G G L EELA GV + SL PI G + QK+K+L + E Sbjct: 63 GDDGGDVLSYILAVEELAKYDAGVAITLSATVSLCANPIWQFGTEAQKEKFLVPLVEGTK 122 Query: 155 MCAYCVTEPGAGSDVAGIKTKAEKKGD-EYIINGQKMWITNGGKANWYFLLARSDPDPKA 213 + A+ +TEP AG+D +G +T A K D Y +NG K++ITNGG A+ Y + A +D K+ Sbjct: 123 LGAFGLTEPNAGTDASGQQTIATKNDDGTYTLNGSKIFITNGGAADIYIVFAMTD---KS 179 Query: 214 PANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVA 273 N T FI+E TPG G+KE MG S T +VF+DVKVP EN+L +G GFK+A Sbjct: 180 KGNHGITAFILEDGTPGFTYGKKEDKMGIHTSQTMELVFQDVKVPAENMLGEEGKGFKIA 239 Query: 274 MGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELA 333 M D R VAA A+G+A+ AL +A +Y+ +R FGK L + Q+ISF LA+M M++E A Sbjct: 240 MMTLDGGRIGVAAQALGIAEAALADAVEYSKQRVQFGKPLCKFQSISFKLADMKMQIEAA 299 Query: 334 RMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRD 393 R +AA + G+ T A+IAK A D+A ++ T+AVQI GG G++ EYPV + MRD Sbjct: 300 RNLVYKAACKKQEGKPFTVDAAIAKRVASDVAMRVTTEAVQIFGGYGYSEEYPVARHMRD 359 Query: 394 AKIYQIYEGTSQIQRLI 410 AKI QIYEGT+++Q ++ Sbjct: 360 AKITQIYEGTNEVQLMV 376 >6FAH-C nrPDB Length = 379 Score = 251 bits (641), Expect = 4e-67, Method: Compositional matrix adjust. Identities = 143/375 (38%), Positives = 221/375 (58%), Gaps = 7/375 (1%) Query: 41 FTEQQKEFQATARKFAREEIIP-VAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLG 99 F+EQ K + AR FA +E+ + E +++GE+P ++ + + G IP++ GG G Sbjct: 3 FSEQNKMIRKLARDFAEKELTTEILDEVEESGEFPQEILDKMAKFGFFGIKIPKSLGGSG 62 Query: 100 LGTFDACLISEELAYGCTGVQTAI--EGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCA 157 + EE A +GV + NSL P++++G ++Q +KYL + A Sbjct: 63 GDHMSYVICMEEFAR-VSGVASVYLSSPNSLAGGPLLLSGTEEQIEKYLKPIITGKKKLA 121 Query: 158 YCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANK 217 + +TEPGAGSD G+ T A GD Y++NG+K +IT + + A++D + + Sbjct: 122 FALTEPGAGSDAGGMSTTAVDMGDYYLLNGRKTFITMAPLCDDAVIYAKTD---MSKGTR 178 Query: 218 AFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAF 277 + FIV+ + G+ +G+ E MG T I+ EDVKVPKEN L GF AM Sbjct: 179 GISAFIVDLKSEGVSMGKNEHKMGLIGCATSDIIMEDVKVPKENRLGEVNKGFSNAMKTL 238 Query: 278 DKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSY 337 D R VA+ ++G+AQ ALDEA KYA ERK FGK + + QAI+FM+A+MA K+E A++ Sbjct: 239 DVGRLGVASQSIGVAQGALDEAIKYAKERKQFGKRIADFQAIAFMIADMATKLEAAKLLV 298 Query: 338 QRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIY 397 AA +D+ + T AS+AK +A +I N++ AVQI GG G+ EY VE++ RD +++ Sbjct: 299 YNAASLMDNKKNATKEASMAKFYASEICNEICAKAVQIHGGYGYIKEYKVERMYRDCRVF 358 Query: 398 QIYEGTSQIQRLIVA 412 IYEGTSQ+Q+++++ Sbjct: 359 TIYEGTSQVQQMVIS 373 >4KTO-A nrPDB Length = 410 Score = 249 bits (637), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 144/380 (37%), Positives = 212/380 (55%), Gaps = 4/380 (1%) Query: 36 GFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENC 95 G +F E+ +A+ R+FA E I P+A + D++ +P+ L R ELGL+ E Sbjct: 28 GLNFALGEEIDALRASVRRFASERIAPLADDADRSNAFPMSLWREMGELGLLGITADEAH 87 Query: 96 GGLGLGTFDACLISEELAYGCTGVQTAIEGNS-LGQMPIIIAGNDQQKKKYLGRMTEEPL 154 GG GLG C+ EE++ V + +S L I G QK +YL ++ Sbjct: 88 GGAGLGYLAHCVAMEEISRASASVGLSYGAHSNLCVNQINRNGKPAQKSRYLPKLISGEH 147 Query: 155 MCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAP 214 + A ++EPGAGSDV +K KA+K+GD Y++NG KMWITNG A+ + A++DP A Sbjct: 148 VGALAMSEPGAGSDVVSMKLKADKRGDRYVLNGSKMWITNGPDADVLVVYAKTDP---AA 204 Query: 215 ANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAM 274 + T F+VE PG G+K +G R S+T ++F D +VP+ENVL G G G KV M Sbjct: 205 GPRGITAFLVEKAFPGFSAGQKLDKLGMRGSNTSELIFTDCEVPEENVLGGVGEGVKVLM 264 Query: 275 GAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELAR 334 D R V++AG +G+ LD Y ERK FG+ + E Q + LA+M + + AR Sbjct: 265 SGLDYERVVLSAGPLGIMAACLDVVVPYLHERKQFGQPIGEFQLMQGKLADMYVTMNAAR 324 Query: 335 MSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDA 394 A D G A+ +A + A +A +A+Q LGGNG+ +YP +L+RDA Sbjct: 325 AYVYAVAAACDRGETARKDAAGCILYAAEKATAMALEAIQALGGNGYTNDYPAGRLLRDA 384 Query: 395 KIYQIYEGTSQIQRLIVARE 414 K+Y+I GTS+I+R+++ RE Sbjct: 385 KLYEIGAGTSEIRRMLIGRE 404 >2DVL-A nrPDB Length = 372 Score = 249 bits (635), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 153/375 (40%), Positives = 222/375 (59%), Gaps = 9/375 (2%) Query: 41 FTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGL 100 T++Q+ R+ ARE + P+A EYD+ EYP P ++ ELGL+ PE GG+GL Sbjct: 3 LTQEQRLVLDAVRRVAREVLYPLAPEYDRKAEYPWPQLKALAELGLLGMTTPEEWGGVGL 62 Query: 101 GTFDACLISEELAYGCTGVQTAIEGNS-LGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYC 159 + L EELA V + S L Q ++ G++ QK++YL + + A+C Sbjct: 63 DSVTWALALEELAAADPSVAVIVSVTSGLPQYMLLRFGSEAQKRRYLVPLARGEWIGAFC 122 Query: 160 VTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAF 219 +TEP AGSD ++ +A + +++NG K WIT+ G A+ Y ++AR++ K Sbjct: 123 LTEPQAGSDAKSLRAEARRVKGGFVLNGVKSWITSAGHAHLYVVMARTE--------KGI 174 Query: 220 TGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDK 279 + F+VE TPG+ GR E MG + T + E+V VP+EN+L +G G A+ D Sbjct: 175 SAFLVEKGTPGLSFGRPEEKMGLHAAHTAEVRLEEVFVPEENLLGEEGRGLAYALAGLDS 234 Query: 280 TRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQR 339 R VAA AVG+A+ A + A YA ER+ FGK L EHQAI+F +A+M +K+ AR Sbjct: 235 GRVGVAAQAVGIARGAFEIAKAYAEEREQFGKKLKEHQAIAFKIADMHVKIAAARALVLE 294 Query: 340 AAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQI 399 AA + D G R T AS AK FA A ++ +AVQ+LGG G++ +Y VE+ RDAK+ +I Sbjct: 295 AARKKDRGERFTLEASAAKLFASAAAVEVTREAVQVLGGYGYHRDYRVERYYRDAKVTEI 354 Query: 400 YEGTSQIQRLIVARE 414 YEGTS+IQRL++ARE Sbjct: 355 YEGTSEIQRLVIARE 369 >2JIF-A nrPDB Length = 404 Score = 247 bits (630), Expect = 8e-66, Method: Compositional matrix adjust. Identities = 141/378 (37%), Positives = 219/378 (57%), Gaps = 6/378 (1%) Query: 41 FTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGL 100 FT+++ +++ +KFA+E+I P+ + D+ + +I+ ++ GLM + GG G Sbjct: 29 FTDEEMMIKSSVKKFAQEQIAPLVSTMDENSKMEKSVIQGLFQQGLMGIEVDPEYGGTGA 88 Query: 101 GTFDACLISEELAYGCTGVQTAIE-GNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYC 159 L+ EELA V E N+L I G ++QK YL ++T E + ++C Sbjct: 89 SFLSTVLVIEELAKVDASVAVFCEIQNTLINTLIRKHGTEEQKATYLPQLTTEKV-GSFC 147 Query: 160 VTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAF 219 ++E GAGSD +KT+A+K+GD Y++NG KMWI++ A + ++A DP K Sbjct: 148 LSEAGAGSDSFALKTRADKEGDYYVLNGSKMWISSAEHAGLFLVMANVDP---TIGYKGI 204 Query: 220 TGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDK 279 T F+V+ DTPG+ IG+ E +G R S T + FE+VKVP+ N+L G G+K A+G+ ++ Sbjct: 205 TSFLVDRDTPGLHIGKPENKLGLRASSTCPLTFENVKVPEANILGQIGHGYKYAIGSLNE 264 Query: 280 TRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQR 339 R +AA +GLAQ D Y ER FGK L + Q + +A +A ++E AR+ Sbjct: 265 GRIGIAAQMLGLAQGCFDYTIPYIKERIQFGKRLFDFQGLQHQVAHVATQLEAARLLTYN 324 Query: 340 AAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQI 399 AA +++G+ AS+AK +A +IA Q + ++ +GG G+ +YPVEK RDAKI I Sbjct: 325 AARLLEAGKPFIKEASMAKYYASEIAGQTTSKCIEWMGGVGYTKDYPVEKYFRDAKIGTI 384 Query: 400 YEGTSQIQRLIVAREHID 417 YEG S IQ +A+ HID Sbjct: 385 YEGASNIQLNTIAK-HID 401 >2Z1Q-A nrPDB Length = 577 Score = 246 bits (629), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 144/390 (36%), Positives = 218/390 (55%), Gaps = 26/390 (6%) Query: 40 EFTEQQKEFQATARKFAREEIIPVAAEYDKTG-EYPVPLIRRAWELGLMNTHIPENCGGL 98 +F E KE T R F E++P+ + E VPL+R+A ELGL+ +PE GGL Sbjct: 27 DFDESVKEIARTTRTFVEREVLPLLERMEHGELELNVPLMRKAGELGLLAIDVPEEYGGL 86 Query: 99 GLGTFDACLISEELAYGCTGVQTAIEGN-SLGQMPIIIAGNDQQKKKYLGRMTEEPLMCA 157 L + +++EEL+ G G + S+G +P++ G ++QK+KYL ++ + A Sbjct: 87 DLPKVISTVVAEELS-GSGGFSVTYGAHTSIGTLPLVYFGTEEQKRKYLPKLASGEWIAA 145 Query: 158 YCVTEPGAGSDVAGIKTKA--EKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA 215 YC+TEPG+GSD KT+A + G YI+NG K WI+N G A+ + + A+ D Sbjct: 146 YCLTEPGSGSDALAAKTRATLSEDGKHYILNGVKQWISNAGFAHLFTVFAKVD------- 198 Query: 216 NKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMG 275 + FT F+VE DTPG+ G +E MG + S TR ++ EDVKVP ENVL G G K+A Sbjct: 199 GEHFTAFLVERDTPGLSFGPEEKKMGIKASSTRQVILEDVKVPVENVLGEIGKGHKIAFN 258 Query: 276 AFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARM 335 + R + AGAVG A+RAL+ + +YA +R FG+ + I L EMA ++ A Sbjct: 259 VLNVGRYKLGAGAVGGAKRALELSAQYATQRVQFGRPIGRFGLIQQKLGEMASRIYAAES 318 Query: 336 SYQRAAWEVDS---GRRN-----------TYYASIAKAFAGDIANQLATDAVQILGGNGF 381 + R +D G++ ASI K ++ + + + VQI GG G+ Sbjct: 319 AVYRTVGLIDEALLGKKGPEAVMAGIEEYAVEASIIKVLGSEVLDYVVDEGVQIHGGYGY 378 Query: 382 NTEYPVEKLMRDAKIYQIYEGTSQIQRLIV 411 + EYP+E+ RDA+I +I+EGT++I RL++ Sbjct: 379 SQEYPIERAYRDARINRIFEGTNEINRLLI 408 >4M9A-A nrPDB Length = 385 Score = 243 bits (621), Expect = 8e-65, Method: Compositional matrix adjust. Identities = 142/375 (37%), Positives = 216/375 (57%), Gaps = 4/375 (1%) Query: 41 FTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGL 100 +TE Q+ AR F E + P AA++D+ P ++ + ELG + +P + GG Sbjct: 13 YTEDQRMILDAARAFCAEVLAPNAAQWDRESHLPDEVVAQMGELGFLGMIVPADWGGSYT 72 Query: 101 GTFDACLISEELAYGCTGVQTAIE-GNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYC 159 L EE+A GC T + NS+G P++ G +QK+++L + + A+ Sbjct: 73 DYVAYALALEEIAAGCASCATLVSVHNSVGCGPVLNYGTTEQKERWLRDLASGKTVGAFS 132 Query: 160 VTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAF 219 +TEP AGS+ ++T+AE + ++I+NG K ++TNG +A + A +DPD + Sbjct: 133 LTEPHAGSEAHNLRTRAELRDGKWILNGSKQFVTNGARAGLAIVFAMTDPDE---GKRGL 189 Query: 220 TGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDK 279 + F+V DTPG +G+ E MG R SDT I E+ +P+EN+L G G K+A+ + Sbjct: 190 SAFVVPTDTPGFIVGKPEKKMGIRASDTCPITLENCAIPQENLLGKRGEGLKIALSNLEG 249 Query: 280 TRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQR 339 R +AA A G+A+ A D A +YA ER FGK + EHQAI+ LA MA ++ AR+ Sbjct: 250 GRIGIAAQATGIARAAFDRARRYARERVQFGKPIAEHQAIAEKLANMATQINAARLLTHH 309 Query: 340 AAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQI 399 AA +G AS AK FA ++A + +DA+QI GG GF +Y VE+ RDA+I QI Sbjct: 310 AARLRTAGLPCLSEASQAKLFASEMAEAVCSDAIQIHGGYGFLVDYEVERHYRDARITQI 369 Query: 400 YEGTSQIQRLIVARE 414 YEGTS++QR+++AR+ Sbjct: 370 YEGTSEVQRMVIARQ 384 >1RX0-A nrPDB Length = 393 Score = 240 bits (612), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 130/391 (33%), Positives = 219/391 (56%), Gaps = 9/391 (2%) Query: 24 HTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWE 83 H +P +G + E+QKEFQ A FA E+ P AE+D+ +PV ++R+A + Sbjct: 6 HRSLTSCIDPSMGLN----EEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQ 61 Query: 84 LGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKK 143 LG +I + GG GL D +I E LA GCT I +++ I GN++Q+ Sbjct: 62 LGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRH 121 Query: 144 KYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFL 203 K+ + +YC+TEPG+GSD A + T A+K+GD YI+NG K +I+ G+++ Y + Sbjct: 122 KFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVV 181 Query: 204 LARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVL 263 + R+ P K + +VE TPG+ G+KE +G TR ++FED VP N + Sbjct: 182 MCRTG----GPGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRI 237 Query: 264 IGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFML 323 +G GF +A+ + R +A+ ++G A ++ + RK FG+ L +Q + F L Sbjct: 238 GSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTL 297 Query: 324 AEMAMKVELARMSYQRAAWEVDSGRRNTY-YASIAKAFAGDIANQLATDAVQILGGNGFN 382 A+MA ++ AR+ + AA + R++ S+AK FA D + A+Q+ GG G+ Sbjct: 298 ADMATRLVAARLMVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYL 357 Query: 383 TEYPVEKLMRDAKIYQIYEGTSQIQRLIVAR 413 +Y V++ +RD++++QI EG++++ R++++R Sbjct: 358 KDYAVQQYVRDSRVHQILEGSNEVMRILISR 388 >3NF4-A nrPDB Length = 387 Score = 239 bits (610), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 141/372 (37%), Positives = 212/372 (56%), Gaps = 5/372 (1%) Query: 42 TEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLG 101 +++ E R+ A + + P+ ++K YP + + GL++ PE GG G Sbjct: 17 SQEAAELIELTREIADKVLDPIVDRHEKDETYPEGVFEQLGAAGLLSLPQPEEWGGGGQP 76 Query: 102 TFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVT 161 + EE+A V A+ +SL P+++ G ++QKK++L M + AY ++ Sbjct: 77 YEVYLQVLEEIAARWASVAVAVSVHSLSSHPLLVFGTEEQKKRWLPGMLSGEQIGAYSLS 136 Query: 162 EPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTG 221 EP AGSD A ++ A Y+ING K WIT+GGKA++Y L AR+ ++ + Sbjct: 137 EPQAGSDAAALRCAATPTDGGYVINGSKSWITHGGKADFYTLFART-----GEGSRGVSC 191 Query: 222 FIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTR 281 F+V AD PG+ G+ E MG T +++ ++ + + +G G ++A A D R Sbjct: 192 FLVPADQPGLSFGKPEEKMGLHAVPTTSAFYDNARIDADRRIGEEGQGLQIAFSALDSGR 251 Query: 282 PVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAA 341 +AA A GLAQ ALDEA YA ER FG+ +++HQ + F+LA+MA V AR +Y AA Sbjct: 252 LGIAAVATGLAQAALDEAVAYANERTAFGRKIIDHQGLGFLLADMAAAVATARATYLDAA 311 Query: 342 WEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYE 401 D GR + ASIAK A D A ++ TDAVQ+ GG G+ +Y VE+ MR+AKI QI+E Sbjct: 312 RRRDQGRPYSQQASIAKLTATDAAMKVTTDAVQVFGGVGYTRDYRVERYMREAKIMQIFE 371 Query: 402 GTSQIQRLIVAR 413 GT+QIQRL++AR Sbjct: 372 GTNQIQRLVIAR 383 >4O5M-A nrPDB Length = 390 Score = 238 bits (606), Expect = 5e-63, Method: Compositional matrix adjust. Identities = 134/379 (35%), Positives = 207/379 (54%), Gaps = 4/379 (1%) Query: 37 FSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCG 96 +F E+ + + T R+FA I P+AAE D+ ++P+ L R ELG++ PE+ G Sbjct: 9 MNFGLGEEIEALRDTVRRFAESRIAPLAAETDRNNQFPMHLWREFGELGVLGITAPEDYG 68 Query: 97 GLGLGTFDACLISEELAYGCTGVQTAIEGNS-LGQMPIIIAGNDQQKKKYLGRMTEEPLM 155 G G+G C+ EE++ + + +S L I G+ +Q+ KYL ++ + Sbjct: 69 GAGMGYLAHCIAMEEISRASASIGLSYGAHSNLCVNQITRNGSPEQRAKYLPKLISGEHV 128 Query: 156 CAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA 215 A ++EPGAGSDV +K AEK+GD Y++NG KMWITNG A+ + A++D + Sbjct: 129 GALAMSEPGAGSDVVSMKLAAEKRGDRYVLNGNKMWITNGPDADVLVVYAKTD---LSAG 185 Query: 216 NKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMG 275 + + FI+E G +K +G R S+T +VFED +VP EN+L +G G V M Sbjct: 186 PRGISAFIIEKGFKGFSTAQKLDKLGMRGSNTCELVFEDCEVPAENLLGTEGKGVNVLMS 245 Query: 276 AFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARM 335 D R V+A G +G+ LD Y ERK F + + E Q + LA+M + +R Sbjct: 246 GLDYERVVLAGGPLGIMAACLDVVVPYVHERKQFDQPIGEFQLMQCKLADMYVTFNASRA 305 Query: 336 SYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAK 395 A D G A+ ++ + A Q+A A+Q LGGNG+ +YP +L+RDAK Sbjct: 306 YVYAVAAACDRGETTRKDAAGCILYSAENATQMALQAIQSLGGNGYINDYPTGRLLRDAK 365 Query: 396 IYQIYEGTSQIQRLIVARE 414 +Y+I GTS+I+R+++ RE Sbjct: 366 LYEIGAGTSEIRRMLIGRE 384 >4IV6-A nrPDB Length = 388 Score = 236 bits (601), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 133/380 (35%), Positives = 218/380 (57%), Gaps = 3/380 (0%) Query: 38 SFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGG 97 S T +++ T F +++ PV E + YP LI E+G+ IPE G Sbjct: 4 SMALTAEEETIVKTVHDFVEKQVKPVVRELEHANTYPEELIETMKEIGIFGLAIPEPYGF 63 Query: 98 LGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCA 157 + ++EELA G + A+ G+++ +++ G ++QK+KYL RM L Sbjct: 64 GAVSMPCYVQVAEELARGWMSLAGAMGGHTVVSKLLLLFGTEEQKQKYLPRMATGELRAT 123 Query: 158 YCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANK 217 +TEPG GSD+ ++T A + GD+Y+ING K WI+N +++ L+ ++DPD + PA+K Sbjct: 124 MALTEPGGGSDLQAMRTVARRDGDDYVINGSKTWISNARRSDLVALMCKTDPDAQ-PAHK 182 Query: 218 AFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGD-GAGFKVAMGA 276 + +VE PG + R +G + ++ + F D +VP ++L D G GF M Sbjct: 183 GVSILLVE-KVPGFDVSRDLPKLGYKGVESCELNFTDARVPVSSLLGDDEGRGFAQMMKG 241 Query: 277 FDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMS 336 + R VAA A G+A+ A ++A +Y+ ER++FGK + +HQ++ MLA+M K+ AR Sbjct: 242 LEVGRLQVAARATGVARAAFEDALRYSQERESFGKPIWQHQSVGNMLADMGTKLYAARSL 301 Query: 337 YQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKI 396 AA + D+G+R A +AK FA + A Q+A DAV++ GG G++TEY VE+ RDA + Sbjct: 302 LLSAAEKFDAGQRCDMEAGMAKLFASETAMQIALDAVRVHGGYGYSTEYDVERYFRDAPL 361 Query: 397 YQIYEGTSQIQRLIVAREHI 416 + EGT++IQR ++A++ + Sbjct: 362 MIVGEGTNEIQRNVIAKQLV 381 >1IVH-A nrPDB Length = 394 Score = 231 bits (590), Expect = 3e-61, Method: Compositional matrix adjust. Identities = 131/379 (34%), Positives = 204/379 (53%), Gaps = 10/379 (2%) Query: 41 FTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWE----LGLMNTHIPENCG 96 +E+Q++ + T KF +E + P A E D++ E+ +R W+ LG++ P G Sbjct: 13 LSEEQRQLRQTMAKFLQEHLAPKAQEIDRSNEFKN--LREFWKQLGNLGVLGITAPVQYG 70 Query: 97 GLGLGTFDACLISEEL--AYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPL 154 G GLG + L+ EE+ A G G+ N L ++ GN+ QK+KYL ++ Sbjct: 71 GSGLGYLEHVLVMEEISRASGAVGLSYGAHSN-LCINQLVRNGNEAQKEKYLPKLISGEY 129 Query: 155 MCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAP 214 + A ++EP AGSDV +K KAEKKG+ YI+NG K WITNG A+ + A++D P Sbjct: 130 IGALAMSEPNAGSDVVSMKLKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDL-AAVP 188 Query: 215 ANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAM 274 A++ T FIVE PG +K +G R S+T ++FED K+P N+L + G V M Sbjct: 189 ASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLM 248 Query: 275 GAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELAR 334 D R V+A G +GL Q LD Y R+ FG+ + Q + +A+M ++ R Sbjct: 249 SGLDLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACR 308 Query: 335 MSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDA 394 A D G + ++ + A Q+A D +Q GGNG+ ++P+ + +RDA Sbjct: 309 QYVYNVAKACDEGHCTAKDCAGVILYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDA 368 Query: 395 KIYQIYEGTSQIQRLIVAR 413 K+Y+I GTS+++RL++ R Sbjct: 369 KLYEIGAGTSEVRRLVIGR 387 >2CX9-A nrPDB Length = 387 Score = 230 bits (587), Expect = 7e-61, Method: Compositional matrix adjust. Identities = 152/387 (39%), Positives = 228/387 (58%), Gaps = 6/387 (1%) Query: 35 LGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPEN 94 +G FE ++++ R+F + E+ P AAE D+TG +P L+R+ E G+ +PE Sbjct: 1 MGLWFEEGAEERQVLGPFREFLKAEVAPGAAERDRTGAFPWDLVRKLAEFGVFGALVPEA 60 Query: 95 CGGLGLGTFDACLISEELAY--GCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEE 152 GG GL T + E +AY G + A NSL I++AG++ QK+ +L ++ Sbjct: 61 YGGAGLSTRLFARMVEAIAYYDGALALTVASH-NSLATGHILLAGSEAQKEAFLPKLASG 119 Query: 153 PLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPK 212 + A+ +TEPG+GSD A +KTKAEK + +NG K +IT G A Y ++AR+DP P Sbjct: 120 EALGAWGLTEPGSGSDAAALKTKAEKVEGGWRLNGTKQFITQGSVAGVYVVMARTDP-PP 178 Query: 213 APANK--AFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGF 270 +P K + F G+++GRKE +G SDT ++ ED+ VP+E +L G GF Sbjct: 179 SPERKHQGISAFAFFRPERGLKVGRKEEKLGLTASDTAQLILEDLFVPEEALLGERGKGF 238 Query: 271 KVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKV 330 + D R +AA AVGL Q ALD A YA R+ FG+ + E + +SF LAE A ++ Sbjct: 239 YDVLRVLDGGRIGIAAMAVGLGQAALDYALAYAKGREAFGRPIAEFEGVSFKLAEAATEL 298 Query: 331 ELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKL 390 E AR+ Y +AA D+GR T A+ AK FA + A + +A+QILGG G+ +YPVE+ Sbjct: 299 EAARLLYLKAAELKDAGRPFTLEAAQAKLFASEAAVKACDEAIQILGGYGYVKDYPVERY 358 Query: 391 MRDAKIYQIYEGTSQIQRLIVAREHID 417 RDA++ +I EGTS+I +L++AR ++ Sbjct: 359 WRDARLTRIGEGTSEILKLVIARRLLE 385 >3MPI-A nrPDB Length = 397 Score = 229 bits (584), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 137/386 (35%), Positives = 219/386 (56%), Gaps = 10/386 (2%) Query: 37 FSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVP-LIRRAWELGLMNTHIPENC 95 F +++ + Q R F ++I+P A ++D +P +R ELG T IPE Sbjct: 1 MDFNLSKELQMLQKEVRNFVNKKIVPFADQWDNENHFPYEEAVRPMGELGFFGTVIPEEY 60 Query: 96 GGLGL--GTFDACLISEELAYGCTGVQTAIEGNSLG-QMPIIIAGNDQQKKKYLGRMTEE 152 GG G+ G A +++EE+A G + ++ + LG I+ G++ KKKY+ +++ Sbjct: 61 GGEGMDQGWLAAMIVTEEIARGSSALRVQLNMEVLGCAYTILTYGSEALKKKYVPKLSSA 120 Query: 153 PLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPK 212 + + +TEP AGSDV + + AE KGD +++NG K WI+N +A+ A +D K Sbjct: 121 EFLGGFGITEPDAGSDVMAMSSTAEDKGDHWLLNGSKTWISNAAQADVLIYYAYTD---K 177 Query: 213 APANKAFTGFIVEA-DTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFK 271 A ++ + F++E + PGI+ E +G S T + ++VKVPKEN+L G G + Sbjct: 178 AAGSRGLSAFVIEPRNFPGIKTSNLE-KLGSHASPTGELFLDNVKVPKENILGKPGDGAR 236 Query: 272 VAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVE 331 + G+ + TR AAG VGLAQ LD A KY ER+ FGK + + Q M+A+MA++VE Sbjct: 237 IVFGSLNHTRLSAAAGGVGLAQACLDAAIKYCNERRQFGKPIGDFQMNQDMIAQMAVEVE 296 Query: 332 LARMSYQRAAWEVDSGRRNT-YYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKL 390 AR+ +AA D GR N ++AK AG+ ++ A A++ILG G++TEYPV + Sbjct: 297 AARLLAYKAAAAKDEGRLNNGLDVAMAKYAAGEAVSKCANYAMRILGAYGYSTEYPVARF 356 Query: 391 MRDAKIYQIYEGTSQIQRLIVAREHI 416 RDA Y + EG++ I ++I+A + + Sbjct: 357 YRDAPTYYMVEGSANICKMIIALDQL 382 >3OWA-A nrPDB Length = 597 Score = 217 bits (552), Expect = 8e-57, Method: Compositional matrix adjust. Identities = 137/396 (34%), Positives = 207/396 (52%), Gaps = 33/396 (8%) Query: 40 EFTEQQKEFQATARKFAREEIIPVAAEYDKTGEY--PVPLIRRAWELGLMNTHIPENCGG 97 +F+ + K T F E++P EY + E+ V L++ A ELGL+ +PE GG Sbjct: 32 DFSSEHKMIAKTTEDFIVNEVLP-ELEYLEQHEFDRSVRLLKEAGELGLLGADVPEEYGG 90 Query: 98 LGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCA 157 +GL + LI+E+ + T +G +PI++ GN++QKKKYL + + A Sbjct: 91 IGLDKVSSALIAEKFSRAGGFAITHGAHVGIGSLPIVLFGNEEQKKKYLPLLATGEKLAA 150 Query: 158 YCVTEPGAGSDVAGIKTKA--EKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA 215 Y +TEPG+GSD G KT A +G Y++NG+K WITN A+ + + A+ D Sbjct: 151 YALTEPGSGSDALGAKTTARLNAEGTHYVLNGEKQWITNSAFADVFIVYAKID------- 203 Query: 216 NKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMG 275 + F+ FIVE D G+ +E MG +CS TR ++ ED VPKEN+L G G +A Sbjct: 204 GEHFSAFIVEKDYAGVSTSPEEKKMGIKCSSTRTLILEDALVPKENLLGEIGKGHIIAFN 263 Query: 276 AFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARM 335 + R + G VG A+RA++ + +YA +R+ F + + I LA MA K A Sbjct: 264 ILNIGRYKLGVGTVGSAKRAVEISAQYANQRQQFKQPIARFPLIQEKLANMAAKTYAAES 323 Query: 336 SYQRAAWEVDSGRRNTY-----------------YA---SIAKAFAGDIANQLATDAVQI 375 S R +S R +T YA S+ K F ++ + + VQI Sbjct: 324 SVYRTVGLFES-RMSTLSEEEVKDGKAVAASIAEYAIECSLNKVFGSEVLDYTVDEGVQI 382 Query: 376 LGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIV 411 GG GF EY +E++ RD++I +I+EGT++I RLIV Sbjct: 383 HGGYGFMAEYEIERMYRDSRINRIFEGTNEINRLIV 418 >6ES9-A nrPDB Length = 551 Score = 215 bits (548), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 130/376 (34%), Positives = 207/376 (55%), Gaps = 14/376 (3%) Query: 53 RKFAREEIIPVAAEYD-KTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEE 111 R++A E +IP A E+ K P+ +I ELG+ IPE GGLGL +++EE Sbjct: 179 RRYAEERVIPNAHEWHLKDQLIPMEIIEELAELGVFGLTIPEEFGGLGLSKASMVVVTEE 238 Query: 112 LAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAG 171 L+ G GV + + + I+ G + QK K+L + ++ TEP GSD+ Sbjct: 239 LSRGYIGVGSLGTRSEIAAELILCGGTEAQKAKWLPGLASGEILSTAVFTEPNTGSDLGS 298 Query: 172 IKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEAD---- 227 ++T+A + G+++++ G K WIT+ + + LLAR+DP+ + + F+ E + Sbjct: 299 LRTRAVRDGEDWVVTGNKTWITHAQRTHVMTLLARTDPE--TTDWRGLSMFLAEKEPGTD 356 Query: 228 -----TPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGD-GAGFKVAMGAFDKTR 281 TPG+ G E+ +G R + F+ ++ EN+L G+ G GFK M F+ R Sbjct: 357 DDPFPTPGMTGGEIEV-LGYRGMKEYELGFDGFRIKGENLLGGEPGRGFKQLMETFESAR 415 Query: 282 PVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAA 341 AA AVG+AQ A + +YA++RK FGK L+E ++ LA MA+++ +AR +A Sbjct: 416 IQTAARAVGVAQSAAEIGMRYAVDRKQFGKSLIEFPRVADKLAMMAVEIMIARQLTYFSA 475 Query: 342 WEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYE 401 WE D GRR A +AK +A A +A+QI GGNGF EY + +++ DA+I I+E Sbjct: 476 WEKDHGRRCDLEAGMAKLLGARVAWAAADNALQIHGGNGFALEYAISRVLCDARILNIFE 535 Query: 402 GTSQIQRLIVAREHID 417 G ++IQ ++AR +D Sbjct: 536 GAAEIQAQVIARRLLD 551 >5IDU-A nrPDB Length = 410 Score = 211 bits (538), Expect = 4e-55, Method: Compositional matrix adjust. Identities = 133/382 (34%), Positives = 209/382 (54%), Gaps = 10/382 (2%) Query: 41 FTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIP-ENCGGLG 99 F + +E A +A + + V ++D T L+R E G + + GG G Sbjct: 26 FEARHRELAAGIEAWATQHLACV--QHDDTDTTCRKLVRALGEAGWLKYGVGGAQYGGHG 83 Query: 100 --LGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCA 157 + T CL+ E LA A+ LG I +AG +QK +YL R+++ + A Sbjct: 84 DTIDTRAVCLLRETLANHDGLADFALAMQGLGSGAITLAGTHEQKIRYLPRVSKGEAIAA 143 Query: 158 YCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANK 217 + ++EP AGSDVA + +A +GD Y+I+G K WI+NGG A++Y + AR+ +AP + Sbjct: 144 FALSEPDAGSDVAAMSLQARAEGDCYVIDGDKTWISNGGIADFYVVFARTG---EAPGAR 200 Query: 218 AFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAF 277 + FIV+ADTPG+QI + +++ R + F+ +VP+ +L G GFK+AM Sbjct: 201 GISAFIVDADTPGLQIAER-IDVIAPHPLAR-LHFDSARVPRSQMLGAPGEGFKIAMRTL 258 Query: 278 DKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSY 337 D R VAA ++G A+RAL E A RK FG+ L + Q LA+MA+ ++ + + Sbjct: 259 DVFRTSVAAASLGFARRALQEGLARAASRKMFGQTLGDFQLTQTKLAQMALTIDSSALLV 318 Query: 338 QRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIY 397 RAAW D G T A++AK A + A Q+ AVQ+ GG G + VE+L R+ + Sbjct: 319 YRAAWLRDQGENVTREAAMAKWHASEGAQQVIDAAVQLWGGMGVQSGTTVERLYREIRAL 378 Query: 398 QIYEGTSQIQRLIVAREHIDKY 419 +IYEG +++Q+LIV R+ + + Sbjct: 379 RIYEGATEVQQLIVGRDLLKAH 400 >2PG0-A nrPDB Length = 385 Score = 210 bits (534), Expect = 9e-55, Method: Compositional matrix adjust. Identities = 130/374 (34%), Positives = 200/374 (53%), Gaps = 5/374 (1%) Query: 43 EQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGT 102 E+ F+A RKF +E P +++K G P + E G + + E GGL Sbjct: 12 EEHHMFRAAFRKFLEKEAYPHYNDWEKRGIIPRSFWAKMGENGFLCPWVDEKYGGLNADF 71 Query: 103 FDACLISEEL-AYGCTGVQTAIEGNSLGQMPIIIA-GNDQQKKKYLGRMTEEPLMCAYCV 160 + +I+EEL G + V + + + P I + G ++QK+K+L + L+ A + Sbjct: 72 AYSVVINEELEKVGSSLVGIGLHNDIV--TPYIASYGTEEQKQKWLPKCVTGELITAIAM 129 Query: 161 TEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFT 220 TEPGAGSD+A I T A K GD YI+NGQK +ITNG A+ + ++DP K P ++ + Sbjct: 130 TEPGAGSDLANISTTAVKDGDYYIVNGQKTFITNGIHADLIVVACKTDPQAKPP-HRGIS 188 Query: 221 GFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKT 280 +VE DTPG GRK +G DT + F+D KVP N+L +G GF M + Sbjct: 189 LLVVERDTPGFTRGRKLEKVGLHAQDTAELFFQDAKVPAYNLLGEEGKGFYYLMEKLQQE 248 Query: 281 RPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRA 340 R VVA A A+ +Y +R FGK + E Q + F LAEMA ++ L R R Sbjct: 249 RLVVAIAAQTAAEVMFSLTKQYVKQRTAFGKRVSEFQTVQFRLAEMATEIALGRTFVDRV 308 Query: 341 AWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIY 400 E +G++ S+AK + ++A ++A +A+Q+ GG G+ EY + + RD + IY Sbjct: 309 IEEHMAGKQIVTEVSMAKWWITEMAKRVAAEAMQLHGGYGYMEEYEIARRYRDIPVSAIY 368 Query: 401 EGTSQIQRLIVARE 414 GT+++ + I+AR+ Sbjct: 369 AGTNEMMKTIIARQ 382 >3R7K-A nrPDB Length = 403 Score = 206 bits (524), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 130/375 (34%), Positives = 203/375 (54%), Gaps = 8/375 (2%) Query: 42 TEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLG 101 T +++ AR F EI P AE++ GE P L A E+GL+ PE GG G Sbjct: 30 TPERRALSQMARSFVEREIAPKLAEWEHVGEIPRDLHLNAAEVGLLGIGFPEEVGGSGGN 89 Query: 102 TFDACLISEEL--AYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYC 159 D+ L++E + A G TGV A+ + + I G+D ++Y+ ++ + Sbjct: 90 AIDSALVTEAILAAGGSTGVCAALFTHGIALPHIAANGSDALIERYVRPTLAGKMIGSLG 149 Query: 160 VTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAF 219 VTEPGAGSDVA ++T+A ++GD Y++NG K +IT+G +A++ R+ P Sbjct: 150 VTEPGAGSDVANLRTRAVREGDTYVVNGAKTFITSGVRADFVTTAVRTG----GPGYGGV 205 Query: 220 TGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDK 279 + +++ ++PG ++ R+ MG RCSDT + F DV+VP +N++ + +GF M F Sbjct: 206 SLLVIDKNSPGFEVSRRLDKMGWRCSDTAELSFVDVRVPADNLVGAENSGFLQIMQQFQA 265 Query: 280 TRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQR 339 R +A A A RALD A +A ER+TFG+ L Q I LAEMA +V++A +Y R Sbjct: 266 ERLGIAVQAYATAGRALDLAKSWARERETFGRPLTGRQIIRHKLAEMARQVDVA-CTYTR 324 Query: 340 AAWEV-DSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQ 398 A + +G S+AK A + + +AVQI GG G+ E +E+ RD +I Sbjct: 325 AVMQRWLAGEDVVAEVSMAKNTAVYACDYVVNEAVQIFGGMGYMRESEIERHYRDCRILG 384 Query: 399 IYEGTSQIQRLIVAR 413 I GT++I ++A+ Sbjct: 385 IGGGTNEIMNEVIAK 399 >5AHS-A nrPDB Length = 401 Score = 202 bits (515), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 120/382 (31%), Positives = 201/382 (52%), Gaps = 4/382 (1%) Query: 39 FEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGL 98 +E T +Q+ Q AR+ A+ A + D T +YP + + + G M +P + GG Sbjct: 2 YELTPEQRTLQTQARELAQSVFASTAVQTDLTEQYPWDNVAQLRDAGFMGMMLPTSVGGR 61 Query: 99 GLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAY 158 GL T D ++ EE+A C + ++LG + I +++ K + A Sbjct: 62 GLSTLDTVIVIEEMAKACATMGRITVDSNLGAIGAITKYGSEEQIKLAADLVLAGDKPAI 121 Query: 159 CVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKA 218 C++EP AGS + + T+A+K GD YI+NG+K WIT GG + + + AR D A Sbjct: 122 CISEPNAGSAASEMTTRADKNGDHYILNGEKYWITGGGVSKLHLIFARVFDDGVEQGIGA 181 Query: 219 FTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLI---GDGAGFKVAMG 275 F + + G+++GR+ MG R + F D+K+ K ++ G GF M Sbjct: 182 FITVLDDHGPEGLKVGRRLYAMGVRGIPETHLEFHDLKIHKSMMITFPDGLKRGFAALMS 241 Query: 276 AFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARM 335 A++ R A A+G+AQ A +E Y R+ FG+ L E Q + +M+A+M++++E AR+ Sbjct: 242 AYNAQRVGAGAVALGIAQCAFEEGVAYLKRREQFGRPLAEFQGLQWMVADMSVQLEAARL 301 Query: 336 SYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAK 395 + AA ++ + A+ AK FA + AN++ DA+Q G +G+ P+E+ +RDA+ Sbjct: 302 MLRSAAVSGET-FPDINKAAQAKIFAAETANKVTNDALQFFGSSGYGRHNPMERHVRDAR 360 Query: 396 IYQIYEGTSQIQRLIVAREHID 417 ++ I GT+QI R VA + +D Sbjct: 361 MFTIAGGTAQILRTQVASKILD 382 >5JSC-A nrPDB Length = 410 Score = 195 bits (496), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 112/309 (36%), Positives = 174/309 (56%), Gaps = 5/309 (1%) Query: 106 CLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGA 165 CL+ E LA A+ LG I + G +QK +YL R+ + A+ ++EP A Sbjct: 92 CLLRETLAKHSGLADFALAMQGLGSGAISLGGTHEQKTRYLPRVANGTAIAAFALSEPEA 151 Query: 166 GSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVE 225 GSDVA + A + GD Y+++G K WI+NGG A++Y + AR+ +AP + + F+V+ Sbjct: 152 GSDVAAMTLSAREDGDAYVLDGDKTWISNGGIADFYVVFARTG---EAPGARGISAFVVD 208 Query: 226 ADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVA 285 ADTPG++I + +++ R + F +VP+ +L G GFK+AM D R VA Sbjct: 209 ADTPGLEIAER-IDVIAPHPLAR-LHFAGARVPRSQMLGAPGEGFKLAMRTLDIFRTSVA 266 Query: 286 AGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVD 345 A ++G A+ A+ E A RK FG+ L + Q LA+MA+ ++ + + RAAW D Sbjct: 267 AASLGFARHAMAEGVARAASRKMFGQTLGDFQLTQAKLAQMALTIDSSALLVYRAAWLRD 326 Query: 346 SGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQ 405 G T A++AK A + A Q+ AVQ+ GG G + VE L R+ + +IYEG ++ Sbjct: 327 QGENVTREAAMAKWHASEGAQQVIDAAVQLYGGMGVQSGTAVEMLYREIRALRIYEGATE 386 Query: 406 IQRLIVARE 414 +Q+LIV R+ Sbjct: 387 VQQLIVGRD 395 >4IRN-A nrPDB Length = 416 Score = 192 bits (489), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 115/388 (29%), Positives = 203/388 (52%), Gaps = 6/388 (1%) Query: 29 RQREPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMN 88 +Q G F F + QQ +F+ +FA++ +I + DK + ++ E G+ Sbjct: 28 QQMGRGSEFDFAWNSQQIQFRKKVIQFAQQSLISDLIKNDKEEIFNRDAWQKCSEFGVHG 87 Query: 89 THIPENCGGLGLGTFDACLISEELAYGC--TGVQTAIEGNSLG-QMPIIIAGNDQQKKKY 145 IP GG L + L YGC G+ A+ + +MP++ G ++QK+KY Sbjct: 88 WPIPARYGGQELDILTTAYALQGLGYGCKDNGLIFAMNAHIWACEMPLLTFGTEEQKEKY 147 Query: 146 LGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLA 205 L + + ++ TEP AGSD+ +KT A+K GD+YI+NG K ++TNG A+ + + A Sbjct: 148 LPLLCRGGWIASHAATEPQAGSDIYSLKTTAQKDGDKYILNGYKHYVTNGTIADLFIIFA 207 Query: 206 RSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIG 265 DP + + T F++E DTPG+ + + MG R ++ + E+ +V N L Sbjct: 208 TIDP---SLGKEGLTTFMIEKDTPGLILSKPISKMGMRTAEVPELRLENCEVSAANRLGE 264 Query: 266 DGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAE 325 +G G + + + R + A AVG +R L+++ +YA K FG+ + + Q ++ L E Sbjct: 265 EGTGLAIFNHSMEWERGFILAAAVGTMERLLEQSIRYARSHKQFGQAIGKFQLVANKLVE 324 Query: 326 MAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEY 385 M +++E A+ + AW ++ + AS+A + + Q +A++I G G+ T Sbjct: 325 MKLRLENAKAYLYKVAWMKENKQMALLEASMANLYISEAWVQSCLEAIEIHGAYGYLTNT 384 Query: 386 PVEKLMRDAKIYQIYEGTSQIQRLIVAR 413 +E+ +RDA + Y GTS+IQR+++A+ Sbjct: 385 ELERELRDAIASKFYSGTSEIQRVVIAK 412 >3P4T-A nrPDB Length = 403 Score = 187 bits (474), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 129/385 (33%), Positives = 198/385 (51%), Gaps = 10/385 (2%) Query: 33 PGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIP 92 PG S T +++ + T R FA E++P A E+++ GE P L R+A ELGL+ P Sbjct: 19 PG-SMSIWTTAEREALRKTVRAFAEREVLPHAHEWERAGEIPRELHRKAAELGLLGAGFP 77 Query: 93 ENCGGLGLGTFDACLISEELAYGCT--GVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMT 150 E+ GG G D +I EE+ Y + GV ++ + +I +G+ + Y+ Sbjct: 78 EDAGGSGGDGADPVVICEEMHYAGSPGGVYASLFTCGIAVPHMIASGDQRLIDTYVRPTL 137 Query: 151 EEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPD 210 + A +TEPG GSDV ++T+A+ GD Y+ING K +IT+G +A++ AR+ Sbjct: 138 RGEKIGALAITEPGGGSDVGHLRTRADLDGDHYVINGAKTYITSGVRADYVVTAARTG-- 195 Query: 211 PKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGF 270 P + +V+ TPG ++ RK MG R SDT + + DV+VP N++ + GF Sbjct: 196 --GPGAGGVSLIVVDKGTPGFEVTRKLDKMGWRSSDTAELSYTDVRVPVANLVGSENTGF 253 Query: 271 KVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKV 330 AF R +A A AQR LD ++ R TFG+ L+ QA+ LA MA ++ Sbjct: 254 AQIAAAFVAERVGLATQAYAGAQRCLDLTVEWCRNRDTFGRPLISRQAVQNTLAGMARRI 313 Query: 331 ELARMSYQRAAWEVDSGRRNTYYASI--AKAFAGDIANQLATDAVQILGGNGFNTEYPVE 388 ++AR+ Y R E A + AK A + +A AVQ+ GG G+ E VE Sbjct: 314 DVARV-YTRHVVERQLAGETNLIAEVCFAKNTAVEAGEWVANQAVQLFGGMGYMAESEVE 372 Query: 389 KLMRDAKIYQIYEGTSQIQRLIVAR 413 + RD +I I GT++I + A+ Sbjct: 373 RQYRDMRILGIGGGTTEILTSLAAK 397 >3B96-A nrPDB Length = 587 Score = 179 bits (455), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 123/346 (35%), Positives = 186/346 (53%), Gaps = 9/346 (2%) Query: 83 ELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEGN-SLGQMPIIIAGNDQQ 141 ELG +P GG+GL + E + GV + + S+G I++ G Q Sbjct: 70 ELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQ 129 Query: 142 KKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKK--GDEYIINGQKMWITNGGKAN 199 K+KYL ++ + A+C+TEP +GSD A I+T A G Y +NG K+WI+NGG A+ Sbjct: 130 KEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLAD 189 Query: 200 WYFLLARSD-PDPKAPANK-AFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKV 257 + + A++ DP A K T F+VE GI G E MG + S+T + F+ V+V Sbjct: 190 IFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRV 249 Query: 258 PKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQ 317 P ENVL G+GFKVAM + R +AA G + + +A +A R FG+ + Sbjct: 250 PSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFG 309 Query: 318 AISFMLAEMAM-KVELARMSYQRAAWEVDSGRRN-TYYASIAKAFAGDIANQLATDAVQI 375 I LA M M + M+Y +A +D G + A+I+K F + A ++ + +QI Sbjct: 310 LIQEKLARMVMLQYVTESMAYMVSA-NMDQGATDFQIEAAISKIFGSEAAWKVTDECIQI 368 Query: 376 LGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREH-IDKYK 420 +GG GF E VE+++RD +I++I+EGT+ I RL VA + +DK K Sbjct: 369 MGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGK 414 >2EBA-A nrPDB Length = 385 Score = 179 bits (454), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 121/376 (32%), Positives = 191/376 (50%), Gaps = 10/376 (2%) Query: 41 FTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGL 100 T ++KE Q AR+F +E +P ++ + G +P LI R ELG + +P GG G+ Sbjct: 11 LTPEEKEVQKAARRFLEKEALPHIRDWWEEGVFPTHLIPRFAELGFLGPTLPPEYGGAGV 70 Query: 101 GTFDACLISEELAYGCTGVQTAIE-GNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYC 159 + LI EL +G+++ + +SL PI G+++QK+++L ++ ++ + Sbjct: 71 SSAAYGLICYELERVDSGLRSFVSVQSSLVMYPIYAYGSEEQKREFLPKLARGEMVGCFG 130 Query: 160 VTEPGAGSDVAG-IKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKA 218 +TEP GSD G +KT+A ++GD +++NG KMWITNG A+ + A+ + Sbjct: 131 LTEPDGGSDPYGNMKTRARREGDTWVLNGTKMWITNGNLAHLAVIWAKDE-------GGE 183 Query: 219 FTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFD 278 GF+V DTPG Q + M R S T +V E+V+VP E++ + G K + Sbjct: 184 VLGFLVPTDTPGFQAREVKRKMSLRASVTSELVLEEVRVP-ESLRLPKALGLKAPLSCLT 242 Query: 279 KTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQ 338 + R +A GA+G + +EA +A R TFG+ L + Q + LAEM + Sbjct: 243 QARFGIAWGAMGALEAVYEEAVAFAKSRSTFGEPLAKKQLVQAKLAEMLAWHTEGLLLAW 302 Query: 339 RAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQ 398 R A D G+ S+AK A Q A A ILGG+G EY + M + + Sbjct: 303 RLARLKDEGKLTPAQVSLAKRQNVWKALQAARMARDILGGSGITLEYHAIRHMLNLETVY 362 Query: 399 IYEGTSQIQRLIVARE 414 YEGT + L++ RE Sbjct: 363 TYEGTHDVHTLVLGRE 378 >3GNC-A nrPDB Length = 399 Score = 155 bits (393), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 116/397 (29%), Positives = 184/397 (46%), Gaps = 17/397 (4%) Query: 18 FHWRSQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPL 77 FHW + L + + ++ + A +A+ ++ P E + + Sbjct: 10 FHW-----------DDPLLLDQQLADDERMVRDAAHAYAQGKLAPRVTEAFRHETTDAAI 58 Query: 78 IRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIE-GNSLGQMPIIIA 136 R E+GL+ IPE GG GL LI+ E+ +G ++ + +SL +PI Sbjct: 59 FREMGEIGLLGPTIPEQYGGPGLDYVSYGLIAREVERVDSGYRSMMSVQSSLVMVPIFEF 118 Query: 137 GNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGG 196 G+D QK+KYL ++ + + +TEP GSD + T+A K Y ++G KMWITN Sbjct: 119 GSDAQKEKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRARKVPGGYSLSGSKMWITNSP 178 Query: 197 KANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVK 256 A+ + + A+ D D + GFI+E G+ +G R S T IV ++ Sbjct: 179 IADVFVVWAKLDEDGR----DEIRGFILEKGCKGLSAPAIHGKVGLRASITGEIVLDEAF 234 Query: 257 VPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEH 316 VP+EN+L G + + R +A GA+G A+ A +Y L+RK FG+ L + Sbjct: 235 VPEENIL-PHVKGLRGPFTCLNSARYGIAWGALGAAESCWHIARQYVLDRKQFGRPLAAN 293 Query: 317 QAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQIL 376 Q I LA+M ++ L R D G SI K + A +A A +L Sbjct: 294 QLIQKKLADMQTEITLGLQGVLRLGRMKDEGTAAVEITSIMKRNSCGKALDIARLARDML 353 Query: 377 GGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAR 413 GGNG + E+ V + + + ++ YEGT I LI+ R Sbjct: 354 GGNGISDEFGVARHLVNLEVVNTYEGTHDIHALILGR 390 >3SF6-A nrPDB Length = 403 Score = 152 bits (383), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 111/383 (28%), Positives = 182/383 (47%), Gaps = 16/383 (4%) Query: 35 LGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPV-PLIRRAWELGLMNTHIPE 93 +G + + +++E + T R + I P A + + GE P L ELGL+ H+ Sbjct: 24 IGINAVLSAEEREIRDTVRSVVQRRIKPHIASWYEDGELPARELAVELGELGLLGMHLKG 83 Query: 94 -NCGGLGLGTFD-ACLISEELAYGCTGVQTAIE-GNSLGQMPIIIAGNDQQKKKYLGRMT 150 C G+ + ACL EL G +G+++ + SL I G+D+QK ++L M Sbjct: 84 YGCAGMSAVAYGLACL---ELEAGDSGIRSLVSVQGSLAMYAIHAFGSDEQKDQWLPDMA 140 Query: 151 EEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPD 210 + + +TEP GSD AG++T+A + GD++I+ G KMWITNG A+ + AR+D Sbjct: 141 SGHRIGCFGLTEPDHGSDPAGMRTRATRSGDDWILTGTKMWITNGSVADVAVVWARTD-- 198 Query: 211 PKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGF 270 + GF+V DTPG + M R S T +V + V++P L G Sbjct: 199 ------EGIRGFVVPTDTPGFTANTIKSKMSLRASVTSELVLDGVRLPDSARLPG-ATSL 251 Query: 271 KVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKV 330 + ++ R + GA+G A+ L+ A YA R+ F + + Q LA+M ++ Sbjct: 252 GAPLRCLNEARFGIVFGALGAARDCLETALAYACSREQFDRPIGGFQLTQQKLADMTLEY 311 Query: 331 ELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKL 390 + + D+G S+ K A ++A A +LG +G EYPV + Sbjct: 312 GKGFLLALHLGRQKDAGELAPEQVSLGKLNNVREAIEIARTARTVLGASGITGEYPVMRH 371 Query: 391 MRDAKIYQIYEGTSQIQRLIVAR 413 + + YEGTS++ LI+ + Sbjct: 372 ANNLESVLTYEGTSEMHTLIIGQ 394 >6CY8-B nrPDB Length = 380 Score = 150 bits (380), Expect = 7e-37, Method: Compositional matrix adjust. Identities = 105/379 (27%), Positives = 180/379 (47%), Gaps = 12/379 (3%) Query: 38 SFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCG- 96 +FE+T +Q E A +F +E ++A + +P + G IPE Sbjct: 2 NFEWTHEQAELFEHALRFGKE----LSAPLQEDNGFPRDNWNALGDFGYFGLPIPEKYAK 57 Query: 97 -GLGLGTFDACLISEELAYGCTGVQTAIEGNSLG---QMPIIIAGNDQQKKKYLGRMTEE 152 G G I E L CT G + MPI+ G++ K + L + Sbjct: 58 DGSGFDILTTIKIIEGLGQSCTDTGLLFAGAAHTFACSMPILEHGSETLKHQLLPDLATG 117 Query: 153 PLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPK 212 + A ++E AGSD++ + T A+K+GD Y++NG K ++TNG A++Y + A ++ K Sbjct: 118 RKIAANAISEASAGSDISNLATTAQKEGDYYVLNGGKSYVTNGSIADYYVVYATTN---K 174 Query: 213 APANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKV 272 T F+V +TPGI +G +G R + + F++ + K+ L +G G ++ Sbjct: 175 KHGYLGQTAFVVPRNTPGISVGNDYHKLGLRSAPLNQVFFDNCTIHKDYALGREGQGARI 234 Query: 273 AMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVEL 332 + D R + A VG QR L++ +YA R K + QA+S +A+M +++E Sbjct: 235 FAASMDWERCCLFAIFVGAMQRDLNQCIEYANTRMQGDKTISRFQAVSHRIADMGVRLES 294 Query: 333 ARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMR 392 AR+ AAW+ NT +++K + Q D++++ G G+ E V ++ Sbjct: 295 ARLMLYYAAWQKSQDVDNTKAVAMSKLAISEAFVQSGIDSIRVHGALGYLDEGRVNNSIK 354 Query: 393 DAKIYQIYEGTSQIQRLIV 411 DA ++ GTS IQR ++ Sbjct: 355 DALGSVLFSGTSDIQRELI 373 >4W9U-A nrPDB Length = 395 Score = 150 bits (378), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 112/376 (29%), Positives = 183/376 (48%), Gaps = 9/376 (2%) Query: 40 EFTEQQKEFQATARKFAREEIIP-VAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGL 98 + TE ++ + +A+ FA + ++P V Y + P L + GL+ +PE+ G Sbjct: 18 QLTEDERMIRDSAKAFASDVLLPRVEKAYLEETTDP-ELFHLMGQAGLLGVTLPEDYGAA 76 Query: 99 GLGTFDACLISEELAYGCTGVQTAIE-GNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCA 157 L++ E+ +G ++ + +SL PI G+D+Q+KKYL + L+ Sbjct: 77 NASYVAYGLVAREVERIDSGYRSMMSVQSSLVMYPIYAYGSDEQRKKYLPGLVSGELIGC 136 Query: 158 YCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANK 217 + +TEP AGSD AG+KT+AEK Y ++G KMWI+N A+ + + A+S A + Sbjct: 137 FGLTEPDAGSDPAGMKTRAEKIDGGYRLSGSKMWISNSPIADVFVVWAKS-----AAHDN 191 Query: 218 AFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAF 277 A GFI+E G+ + + R S T IV + V+V E+ ++ + +G K G Sbjct: 192 AIRGFILEKGMKGLSAPKIGGKLSLRASITGEIVMDGVEV-SEDAILPNVSGLKGPFGCL 250 Query: 278 DKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSY 337 ++ R ++ G +G A+ A +Y L+RK F K L Q LA+M ++ L + Sbjct: 251 NRARYGISWGVLGAAEDCWFRARQYGLDRKQFNKPLAGTQLYQKKLADMQTEIALGIQAS 310 Query: 338 QRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIY 397 R D G+ SI K A +A A + GGNG EY V + ++ + Sbjct: 311 LRVGRLFDEGKMAPEMISIVKRNNCGKALDIARQARDMHGGNGIQIEYHVMRHAQNLETV 370 Query: 398 QIYEGTSQIQRLIVAR 413 YEGT + LI+ R Sbjct: 371 NTYEGTHDVHALILGR 386 >4HR3-A nrPDB Length = 415 Score = 141 bits (355), Expect = 6e-34, Method: Compositional matrix adjust. Identities = 117/421 (27%), Positives = 197/421 (46%), Gaps = 40/421 (9%) Query: 33 PGLGFSFEFTEQQKEFQATARKFAREEIIPV----AAEYDK--------TGE-YPVP--- 76 PG F + + E A R+F E++PV A +D+ T E + VP Sbjct: 2 PG-SMDFAPSARAAELIAAVREFIDAEVMPVERAVLAHHDELLGARAGTTAELWHVPPEL 60 Query: 77 --LIRRAWELGLMNTHIPENCGGLGLGTFDACLISEEL--------AYGCTGVQTAIEGN 126 L +A GL N +P+ G GL + ++E++ + C + Sbjct: 61 DSLKAKARAAGLWNLFLPDPELGGGLSNSEYAPLAEQMGRSLFAPTVFNCNAPDS----- 115 Query: 127 SLGQMPIIIA-GNDQQKKKYLGRMTEEPLMCAYCVTEPG-AGSDVAGIKTKAEKKGDEYI 184 G M ++ G+ +QK+ +L + E + A+C+TEP A SD + A +GDE + Sbjct: 116 --GNMEVLHRYGSQEQKEVWLEPLLEGDIRSAFCMTEPDVASSDATNMAATAVVEGDEVV 173 Query: 185 INGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMG-QR 243 ING+K W T G + ++ DP A + +V DTPGI + R MG Sbjct: 174 INGRKWWSTGVGHPDCKVIIFMGLTDPNAHRYARHSMVLVPMDTPGITVERMLPTMGFYD 233 Query: 244 CSDTRGIV-FEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKY 302 G+V F++V++P + + G G GF++A G R A +GLA+ AL+ A + Sbjct: 234 EPGGHGVVSFDNVRLPADAFIAGPGKGFEIAQGRLGPGRVHHAMRLIGLAEVALEHACRR 293 Query: 303 ALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIA--KAF 360 L+R FGK LV +A+ + + R+ AAW +D+ ++++ K Sbjct: 294 GLDRTAFGKPLVNLGGNRERIADARIAINQTRLLVLHAAWLLDTVGIMGALSAVSEIKVA 353 Query: 361 AGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDKYK 420 A ++A Q+ A+QI GG G + ++P+ +A+ ++ +G ++ R +VAR + KY Sbjct: 354 APNMAQQVIDMAIQIHGGGGLSNDFPLAAAWVNARALRLADGPDEVHRGVVARIELAKYA 413 Query: 421 N 421 N Sbjct: 414 N 414 >2IX5-A nrPDB Length = 436 Score = 141 bits (355), Expect = 6e-34, Method: Compositional matrix adjust. Identities = 105/379 (27%), Positives = 175/379 (46%), Gaps = 9/379 (2%) Query: 37 FSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIP-ENC 95 F+ T +++ + R+ +E+ P+ EY + E+P + + +G+ I C Sbjct: 51 FNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIKGYGC 110 Query: 96 GGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLM 155 GL + T +A +E + + +SLG + I + G++ QK+KYL + + + Sbjct: 111 PGLSI-TANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTV 169 Query: 156 CAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA 215 + +TEP GSD +G+ T A K + INGQK WI N A+ + AR+ Sbjct: 170 ACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNT------T 223 Query: 216 NKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMG 275 GFIV+ D PG++ + +G R I+ ++V VP E+ L G + F+ Sbjct: 224 TNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNS-FQDTSK 282 Query: 276 AFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARM 335 +R +VA +G++ D +Y ERK FG L Q L +M V+ + Sbjct: 283 VLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFL 342 Query: 336 SYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAK 395 R ++G+ AS+ KA+ A + A+ ++LGGNG ++ V K D + Sbjct: 343 MGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLE 402 Query: 396 IYQIYEGTSQIQRLIVARE 414 YEGT I L+ RE Sbjct: 403 PIYTYEGTYDINTLVTGRE 421 >1SIR-A nrPDB Length = 394 Score = 140 bits (354), Expect = 8e-34, Method: Compositional matrix adjust. Identities = 105/377 (27%), Positives = 181/377 (48%), Gaps = 12/377 (3%) Query: 40 EFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLG 99 + T + + T R + +E ++P ++ + +I ELG++ I + G G Sbjct: 15 QLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-KGYGCAG 73 Query: 100 LGTFDACLISEELAYGCTGVQTAIE-GNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAY 158 + + L++ EL +G ++A+ +SL PI G+++Q++KYL ++ + L+ + Sbjct: 74 VSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCF 133 Query: 159 CVTEPGAGSDVAGIKTKAE--KKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPAN 216 +TEP +GSD + ++T+A Y +NG K WITN A+ + + AR + + Sbjct: 134 GLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCE-------D 186 Query: 217 KAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGA 276 GF++E G+ R + R S T I+ + V+VP+ENVL G + G Sbjct: 187 GCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPG-ASSLGGPFGC 245 Query: 277 FDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMS 336 + R +A G +G ++ L A +YAL+R FG L +Q I LA+M ++ L + Sbjct: 246 LNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHA 305 Query: 337 YQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKI 396 + D + S+ K A +A A +LGGNG + EY V + + + Sbjct: 306 CLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEA 365 Query: 397 YQIYEGTSQIQRLIVAR 413 YEGT I LI+ R Sbjct: 366 VNTYEGTHDIHALILGR 382 >5ZW7-A nrPDB Length = 402 Score = 140 bits (353), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 101/382 (26%), Positives = 181/382 (47%), Gaps = 12/382 (3%) Query: 39 FEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGL 98 F + Q + +A +FA + + A L ++A G + + GG Sbjct: 3 FNLSNSQSDIYESAYRFACDVLDQDAQTRISQKILSTELWKKAAAYGFAHGPVSHQFGGS 62 Query: 99 GLGTFDACLISEELAYGC--TGVQTAIEGNSLG-QMPIIIAGNDQQKKKYLGRMTEEPLM 155 LG D L+ E L G G+ ++ + +P+ G+ + K KYL + L+ Sbjct: 63 ELGALDTALMIEALGKGSRDIGLSFSLCAHLCACVIPLYRFGSSELKDKYLESLVTGKLI 122 Query: 156 CAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA 215 A TEP AGSD+ ++ A+ YI+NG+K++ITN A+ + + A+++PD Sbjct: 123 AANAATEPDAGSDIYNMQATAQPCEGGYILNGKKIFITNAPIADVFIIYAKTNPD----- 177 Query: 216 NKAFTG---FIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKV 272 F G F++E TPG+ +G IVF D+ +P+ + +GAG + Sbjct: 178 -HGFLGVSAFLIEKGTPGLNVGEVIPKDCLSNCPWSEIVFNDIFIPQSQRIGMEGAGGAI 236 Query: 273 AMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVEL 332 + + ++A VG R L+ +YA R+ FGK + + Q++S + +M +++E Sbjct: 237 FHDSMIWEKGCLSALFVGGLARLLETTLEYAKARQQFGKAIGQFQSVSNRIIDMKLRLEQ 296 Query: 333 ARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMR 392 R+ RA W+ D G+ +++K + A Q DA+Q GG + E + + + Sbjct: 297 CRLMLYRACWKHDQGQDAEADIAMSKLLISEYAVQSGLDAIQTFGGAAMDQELGLVRHLL 356 Query: 393 DAKIYQIYEGTSQIQRLIVARE 414 + +I+ GT+ IQ+ I+AR+ Sbjct: 357 NMIPSRIFSGTNDIQKEIIARK 378 >3SWO-A nrPDB Length = 399 Score = 129 bits (323), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 97/383 (25%), Positives = 175/383 (45%), Gaps = 33/383 (8%) Query: 43 EQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGT 102 + +++ AT R+F + P + ++ P L + LG++ H+ + G G Sbjct: 28 QDERDIAATVRQFVDTRLKPNVEGWFESATLPSELAKEFGNLGVLGMHL-QGYGCAGTNA 86 Query: 103 FDACLISEELAYGCTGVQT--AIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCV 160 L EL G +G ++ +++G SL I G+++QK ++L R+ + + + Sbjct: 87 VSYGLACMELEAGDSGFRSFVSVQG-SLSMFSIYRYGSEEQKNEWLPRLAAGDAIGCFGL 145 Query: 161 TEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFT 220 TEP GS+ AG++T+A + G ++I+NG KMWITNG A+ + A++D Sbjct: 146 TEPDFGSNPAGMRTRARRDGSDWILNGTKMWITNGNLADVATVWAQTD--------DGIR 197 Query: 221 GFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKT 280 GF+V DTPG + R S T +V ++V++P + + G + ++ Sbjct: 198 GFLVPTDTPGFTANEIHRKLSLRASVTSELVLDNVRLPA-SAQLPLAEGLSAPLSCLNEA 256 Query: 281 RPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMA--------MKVEL 332 R + GA+G A+ +L+ Y R+ F K L +Q LA M + + L Sbjct: 257 RFGIVFGALGAARDSLETTIAYTQSREVFDKPLSNYQLTQEKLANMTVELGKGMLLAIHL 316 Query: 333 ARMSYQRAAW--EVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKL 390 R+ ++ G+ N +IA +A + +LGG+G EY + Sbjct: 317 GRIKDAEGVRPEQISLGKLNNVREAIA----------IARECRTLLGGSGITLEYSPLRH 366 Query: 391 MRDAKIYQIYEGTSQIQRLIVAR 413 + + YEGTS++ L + + Sbjct: 367 ANNLESVLTYEGTSEMHLLSIGK 389 >1R2J-A nrPDB Length = 366 Score = 129 bits (323), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 98/353 (27%), Positives = 170/353 (48%), Gaps = 10/353 (2%) Query: 64 AAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAI 123 AAE+D +GE P L+ R GL+ + GGLGLG+ + + + C+ +++ + Sbjct: 16 AAEWDTSGELPRDLLVRLGADGLLCAEVAAEHGGLGLGSRENGEFTAHVGSLCSSLRSVM 75 Query: 124 EGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEY 183 + + G+ Q+ +L +T L A +E AGSD++ ++T+ GD Sbjct: 76 TSQGMAAWTVQRLGDAGQRATFLKELTSGKL-AAVGFSERQAGSDLSAMRTRVRLDGDTA 134 Query: 184 IINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQR 243 +++G K+W T A+ + + A +V ADTPG+++ R G R Sbjct: 135 VVDGHKVWTTAAAYADHLVVFGLQEDGSGAV-------VVVPADTPGVRVERVPKPSGCR 187 Query: 244 CSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGA-FDKTRPVVAAGAVGLAQRALDEATKY 302 + + + V+VP VL G GA + + A R VA G VG+ + A + Sbjct: 188 AAGHADLHLDQVRVPAGAVLAGSGASLPMLVAASLAYGRKSVAWGCVGILRACRTAAVAH 247 Query: 303 ALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASI-AKAFA 361 A R+ FG+ L +HQ ++ +A++ ++A + A+ D G A+I AK A Sbjct: 248 ARTREQFGRPLGDHQLVAGHIADLWTAEQIAARVCEYASDHWDEGSPEMVPATILAKHVA 307 Query: 362 GDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVARE 414 + A A A Q+L G + VE+ RDAK+ +I EG+S++ R+++A+ Sbjct: 308 AERAAAGAATAAQVLASAGAREGHVVERAYRDAKLMEIIEGSSEMCRVMLAQH 360 >2WBI-A nrPDB Length = 428 Score = 124 bits (310), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 105/408 (25%), Positives = 188/408 (46%), Gaps = 43/408 (10%) Query: 36 GFSFEFTEQQKEFQATARKFAREEIIPVAAEY--------DKTGEYPVPL-IRRAWEL-- 84 G F T + +E + F ++ I+P E + ++ PL I + E+ Sbjct: 18 GQLFVQTRKGQEVLIKVKHFMKQHILPAEKEVTEFYVQNENSVDKWGKPLVIDKLKEMAK 77 Query: 85 --GLMNTHIPENCGGLGLGTFDACLISEEL--------AYGCTGVQTAIEGNSLGQMPII 134 GL N +P G L D LI+EE + C T G M ++ Sbjct: 78 VEGLWNLFLPAVSG---LSHVDYALIAEETGKCFFAPDVFNCQAPDT-------GNMEVL 127 Query: 135 -IAGNDQQKKKYLGRMTEEPLMCAYCVTEPG-AGSDVAGIKTKAEKKGDEYIINGQKMWI 192 + G+++QKK++L + + + +C+TEP A SD I+ ++ D Y+ING+K W Sbjct: 128 HLYGSEEQKKQWLEPLLQGNITSCFCMTEPDVASSDATNIECSIQRDEDSYVINGKKWWS 187 Query: 193 TNGG--KANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRG- 249 + G K +L R+ + +K + +V +TPG++I R L++ + G Sbjct: 188 SGAGNPKCKIAIVLGRTQ-NTSLSRHKQHSMILVPMNTPGVKIIRP-LSVFGYTDNFHGG 245 Query: 250 ---IVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALER 306 I F V+VP N+++G+G GF+++ G R VGLA+RAL + A +R Sbjct: 246 HFEIHFNQVRVPATNLILGEGRGFEISQGRLGPGRIHHCMRTVGLAERALQIMCERATQR 305 Query: 307 KTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIA--KAFAGDI 364 F K L H+ ++ +AE + +E R+ +AA +D+ IA K A Sbjct: 306 IAFKKKLYAHEVVAHWIAESRIAIEKIRLLTLKAAHSMDTLGSAGAKKEIAMIKVAAPRA 365 Query: 365 ANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVA 412 +++ A+Q+ GG G + +YP+ + ++ ++ +G ++ +A Sbjct: 366 VSKIVDWAIQVCGGAGVSQDYPLANMYAITRVLRLADGPDEVHLSAIA 413 >3MKH-A nrPDB Length = 438 Score = 123 bits (308), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 111/405 (27%), Positives = 174/405 (42%), Gaps = 42/405 (10%) Query: 35 LGFSFEFTEQQKEFQATARKFAREEIIPVAAEY-DKTGEYPV------PLIRRAWELGLM 87 + F + QK AR AR ++P Y P+ P A G++ Sbjct: 1 MAIDFHLSASQKGTYQAARSLARNLLMPARQTYLQHPPNSPLRFQSTQPTYAAAVSAGIL 60 Query: 88 NTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLG 147 I GG G ++ ++ EE I LG PI +A Q + Sbjct: 61 KGQISPAHGGTGGTLIESAILVEECYSVEPSAALTIFATGLGLTPINLAAGPQHAEFLAP 120 Query: 148 RMTEE--PLMCAYCVTEPGAGSDV-----AGIKTKAEKKGDEYIINGQKMWITNGGKANW 200 ++ E PL + +EPG ++ G +T A +GDE++ING+KMW TN A W Sbjct: 121 FLSGEGSPL-ASLVFSEPGGVANALEKGAPGFQTTARLEGDEWVINGEKMWATN--CAGW 177 Query: 201 YF-------LLARSDPDP----KAPANKAFTGFIVEADTP-----GIQIGRKELNMGQRC 244 F ++ R P + P NK + AD ++ R G Sbjct: 178 DFKGCDLACVVCRDATTPLEEGQDPENKVMIILVTRADLDRNGEGSFEVLRHVATPGHTS 237 Query: 245 SDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYAL 304 + + +V+VP +NVL G G KVA GAFD + +V A VGL + A D A K+A Sbjct: 238 VSGPHVRYTNVRVPTKNVLCPAGQGAKVAFGAFDGSAVLVGAMGVGLMRAAFDAALKFAK 297 Query: 305 ERKTFGKL-LVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSG------RRNTYYASIA 357 E G + L+E QA + +L+ + ++ E AR +AA +++G RR A A Sbjct: 298 EDNRGGAVPLLERQAFADLLSGVKIQTEAARALTWKAAHAMENGPGDYDARRELALA--A 355 Query: 358 KAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEG 402 K F + A + TD + +G + ++ + P L+ A + I++G Sbjct: 356 KVFCSEAAVKACTDVINAVGISAYDLQRPFSDLLNTAVVLPIFDG 400 >4X28-A nrPDB Length = 400 Score = 104 bits (259), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 102/399 (25%), Positives = 176/399 (44%), Gaps = 39/399 (9%) Query: 39 FEFTEQQKEFQATARKF--------AREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTH 90 +T QQ+E + R + RE + V EY Y + + + G + Sbjct: 3 ISYTPQQEELRRELRSYFATLMTPERREALSSVQGEYGVGNVYRETIAQMGRD-GWLALG 61 Query: 91 IPENCGGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIA-GNDQQKKKYLGRM 149 P+ GG G D + ++E A V + NS+ P I+A G D+QK+ +L R+ Sbjct: 62 WPKEYGGQGRSAMDQLIFTDEAAIAGAPVPF-LTINSVA--PTIMAYGTDEQKRFFLPRI 118 Query: 150 TEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDP 209 L + +EPGAG+D+A ++T A + GD+Y++NGQKMW + A++ +L R++P Sbjct: 119 AAGDLHFSIGYSEPGAGTDLANLRTTAVRDGDDYVVNGQKMWTSLIQYADYVWLAVRTNP 178 Query: 210 DPK-APANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGA 268 + A ++ + IV G G DT + DV+VP N + + A Sbjct: 179 ESSGAKKHRGISVLIVPTTAEGFSWTPVHTMAG---PDTSATYYSDVRVPVANRVGEENA 235 Query: 269 GFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTF-GKLLVEHQAISFMLAEMA 327 G+K+ + R + + A L E ++A K G L++ + + LA + Sbjct: 236 GWKLVTNQLNHERVALVSPAPIFG--CLREVREWAQNTKDAGGTRLIDSEWVQLNLARVH 293 Query: 328 MKVELARMSYQRAAWEVDSGRR-------NTYYASIAKAFAGDIANQLATDAVQILG-GN 379 K E+ ++ WE+ S + + AS AK F ++A + +++LG Sbjct: 294 AKAEVLKL----INWELASSQSGPKDAGPSPADASAAKVFGTELATEAYRLLMEVLGTAA 349 Query: 380 GFNTEYP-------VEKLMRDAKIYQIYEGTSQIQRLIV 411 P VE++ R I GT+++QR I+ Sbjct: 350 TLRQNSPGALLRGRVERMHRACLILTFGGGTNEVQRDII 388 >4RM7-A nrPDB Length = 391 Score = 104 bits (259), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 79/267 (29%), Positives = 130/267 (48%), Gaps = 3/267 (1%) Query: 154 LMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKA 213 L A ++EP AGSD ++T ++GD ++NG KM++ NG A LL + Sbjct: 122 LSYALAISEPEAGSDTRSMRTHVTREGDTLVMNGTKMFVNNGEYAP--ALLVSAYDKTGD 179 Query: 214 PANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVA 273 F+ ++V GI E +GQ + F++V+V + L G GF Sbjct: 180 DGEPEFSFWMVPRSAAGI-YAYPEQKIGQSMLPFATVRFDNVEVKESWRLKGSSKGFSQL 238 Query: 274 MGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELA 333 + R A A+G AQ A+++A +A R+ FG+ + + Q + L EM +K+ Sbjct: 239 YSLLEYGRVFTCAAALGEAQAAMEDAVAWARGREAFGQRIADLQQVQMKLTEMEVKLTNM 298 Query: 334 RMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRD 393 R AA E D G ++ K + A ++A+DA+QILGG G+ E V + +D Sbjct: 299 RNLVYGAAREYDRGEHKRLSVALMKYYVPKAATEVASDAMQILGGRGYIQENRVSSIWQD 358 Query: 394 AKIYQIYEGTSQIQRLIVAREHIDKYK 420 + YQ +GT ++ +I A +++YK Sbjct: 359 CRGYQFADGTDEVMVVIAAPLILEQYK 385 >2C12-A nrPDB Length = 439 Score = 99.8 bits (247), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 100/421 (23%), Positives = 183/421 (43%), Gaps = 46/421 (10%) Query: 39 FEFTEQQKEFQATARKFAREEIIPVAAEY----DKTGEYPV--PLIRRAWELGLMNTHIP 92 F+ + Q E + A+ FA + +AEY D+ + P R A GL+ +P Sbjct: 4 FKLSPSQLEARRHAQAFANTVLTKASAEYSTQKDQLSRFQATRPFYREAVRHGLIKAQVP 63 Query: 93 ENCGGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTE- 151 GG +I EEL I +LG MP+I+ + ++K+L Sbjct: 64 IPLGGTMESLVHESIILEELFAVEPATSITIVATALGLMPVILCDSPSLQEKFLKPFISG 123 Query: 152 --EPLMCAYCVTEPGAGSDV-----AGIKTKAEKKGDEYIINGQKMWITNGGK-----AN 199 EPL + +EP ++ G++T A K G+E++I+G+K+W +N G A+ Sbjct: 124 EGEPL-ASLMHSEPNGTANWLQKGGPGLQTTARKVGNEWVISGEKLWPSNSGGWDYKGAD 182 Query: 200 WYFLLARSDPDPKAPAN------KAFTGFIVEADT------PGIQI-GRKELNMGQRCSD 246 ++ R DP P + +V +T QI G EL G + Sbjct: 183 LACVVCRVSDDPSKPQDPNVDPATQIAVLLVTRETIANNKKDAYQILGEPEL-AGHITTS 241 Query: 247 TRGIVFEDVKVPKENVLIGDGAGFK-VAMGAFDKTRPVVAAGAVGLAQRALDEATKYALE 305 F + VP EN+L G + + AF + +V A A+G A+ A +EA +A Sbjct: 242 GPHTRFTEFHVPHENLLCTPGLKAQGLVETAFAMSAALVGAMAIGTARAAFEEALVFAKS 301 Query: 306 RKTFG-KLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDS----GRRNTYYASIAKAF 360 G K ++EHQ+++ L + +++E +R+ +A ++ + A K + Sbjct: 302 DTRGGSKHIIEHQSVADKLIDCKIRLETSRLLVWKAVTTLEDEALEWKVKLEMAMQTKIY 361 Query: 361 AGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTS------QIQRLIVARE 414 D+A + DA++ +G + + +L+ + Y +++G + Q+QR++ + Sbjct: 362 TTDVAVECVIDAMKAVGMKSYAKDMSFPRLLNEVMCYPLFDGGNIGLRRRQMQRVMALED 421 Query: 415 H 415 + Sbjct: 422 Y 422 >5GJ7-A nrPDB Length = 398 Score = 75.1 bits (183), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 90/357 (25%), Positives = 149/357 (41%), Gaps = 46/357 (12%) Query: 64 AAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAI 123 A E+D+ G++P I G + +P GGLGL + + E LA G AI Sbjct: 35 APEHDRAGDFPFENIEDLKASGYVRWTVPVEYGGLGLSLEEMLMHQEVLAKGDGSTALAI 94 Query: 124 EGNSLGQMPIII---AGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIK--TKAEK 178 G +G + + A D+ + + +E + C TEP GS G K T A K Sbjct: 95 -GWHVGILLHLRETGAFPDELFRMVCESVVKEGALINSCATEPATGSPSRGGKPETTAVK 153 Query: 179 KGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTG-FIVEADTPGIQIGRKE 237 Y I G+K + T W + A A++ G F+V + ++I Sbjct: 154 VPGGYRITGRKTFSTLSPALTWIMVTATV-------ADEDVVGQFLVRKED--VEIVETW 204 Query: 238 LNMGQRCSDTRGIVFEDVKVPKENVLI-----------GDGAGFKVAMGAFDKTRPVVAA 286 +G R + + IV +DV VP+E V++ DG+G+ + + A Sbjct: 205 DTLGMRATGSHDIVLKDVFVPEERVIVIQRPGVQAERRPDGSGWLLH----------IPA 254 Query: 287 GAVGLAQRALDEATKYALERK--TFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEV 344 +G+A A D A +YA + T + E + L EM +K+ AR A Sbjct: 255 CYLGIALAARDFALEYAATYRPNTLPHPIAEVPHVEQKLGEMELKLLAARTLLYDLARRF 314 Query: 345 DSG------RRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAK 395 D+ + + ++ K A + ANQ+ A++++GG + P+E+ RD + Sbjct: 315 DAASPEERVKLQPQFGAV-KTLATNAANQVVDLAMRVVGGRSLSRALPLERYYRDVR 370 >5EZ3-A nrPDB Length = 573 Score = 73.9 bits (180), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 72/268 (26%), Positives = 120/268 (44%), Gaps = 27/268 (10%) Query: 160 VTEPGAGSDVAGIKTKAEKK-GDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKA 218 +TE G+DV T+AE G + + G K W + ++ + LA++ + Sbjct: 213 MTEKQGGTDVRANATRAEPAIGGAWRLTGHK-WFMSAPMSDAFLTLAQT--------KEG 263 Query: 219 FTGFIV-----EADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGD-GAGFKV 272 + F++ + ++ G R + +G R + + + F+ +IG G G K Sbjct: 264 LSCFLLPRLGEKGESNGFFFQRLKDKLGNRSNASSEVEFDGAL----GQMIGSPGEGVKT 319 Query: 273 AMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVEL 332 M TR A + GL + L EA ++ R FGK LVE + +LA+MA+ V Sbjct: 320 IMDMVTLTRLDCAVASAGLMRSGLAEAVHHSRHRHVFGKPLVEQPLMQRVLADMALDVAG 379 Query: 333 ARMSYQRAAWEVD---SGRRNTYYA----SIAKAFAGDIANQLATDAVQILGGNGFNTEY 385 A R A D S R +A + K + IA L +A++ LGGNG+ + Sbjct: 380 ATALSMRLARAFDMAASDRAEAAFARSMTPVVKYWVCKIAPALLYEAMECLGGNGYIEDG 439 Query: 386 PVEKLMRDAKIYQIYEGTSQIQRLIVAR 413 + + R+A + I+EG+ + L VAR Sbjct: 440 NLARAYREAPVNAIWEGSGNVMALDVAR 467 >3U33-A nrPDB Length = 541 Score = 70.5 bits (171), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 69/274 (25%), Positives = 121/274 (44%), Gaps = 28/274 (10%) Query: 154 LMCAYCVTEPGAGSDVAGIKTKAEKKGD-EYIINGQKMWITNGGKANWYFLLARSDPD-P 211 L+ +TE GSDV T+AE+ D Y + G K W+F + +SD Sbjct: 178 LLIGMGMTEKQGGSDVMSNTTRAERLEDGSYRLVGHK----------WFFSVPQSDAHLV 227 Query: 212 KAPANKAFTGFIVEADTP-----GIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIG- 265 A + F V P I++ R + +G R + + + F+D L+G Sbjct: 228 LAQTAGGLSCFFVPRFLPDGQRNAIRLERLKDKLGNRSNASCEVEFQDAI----GWLLGL 283 Query: 266 DGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAE 325 +G G ++ + TR A G+ + +RA A +A +R FG L++ + +L+ Sbjct: 284 EGEGIRLILKMGGMTRFDCALGSHAMMRRAFSLAIYHAHQRHVFGNPLIQQPLMRHVLSR 343 Query: 326 MAMKVE--LARMSYQRAAWEVDSGRRNTYYASI----AKAFAGDIANQLATDAVQILGGN 379 MA+++E A + AW+ + + +A + AK +A+++LGG Sbjct: 344 MALQLEGQTALLFRLARAWDRRADAKEALWARLFTPAAKFVICKRGMPFVAEAMEVLGGI 403 Query: 380 GFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAR 413 G+ E + +L R+ + I+EG+ I L V R Sbjct: 404 GYCEESELPRLYREMPVNSIWEGSGNIMCLDVLR 437 >3M9V-A nrPDB Length = 439 Score = 68.6 bits (166), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 84/358 (23%), Positives = 145/358 (40%), Gaps = 34/358 (9%) Query: 59 EIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLG-TFDACLISEELAYGCT 117 I AAE+D+ G +P + GLM +P GGLG+ +D + +A Sbjct: 37 RIRSTAAEHDRDGTFPTDTFDALRKDGLMGATVPAELGGLGVDRLYDVAVALLAVARADA 96 Query: 118 GVQTAIE-----GNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGI 172 A+ G +LG + ++ + L ++ V G + Sbjct: 97 STALALHMQLSRGLTLGYE----WRHGDERARTLAERILRGMVAGDAVVCSGIKDHHTAV 152 Query: 173 KTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQ 232 T ++++G+K ++ + + AR+D P +V DTPG Sbjct: 153 TTLRPDGAGGWLLSGRKTLVSMAPVGTHFVINARTDGTDGPPR---LASPVVTRDTPGFT 209 Query: 233 IGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKV-AMGAFDKTRPVVAAGA-VG 290 + +G R S T IVF+D +P ++VL+ D G + A+ A V G VG Sbjct: 210 VLDNWDGLGMRASGTVDIVFDDCPIPADHVLMRDPVGARNDAVLAGQTVSSVSVLGVYVG 269 Query: 291 LAQRALDEATKYALERKTFGKLLVEHQAISFML-AEMAMKVELARMSYQRAAWEVDS--- 346 +AQ A D A ALER+ QA + L AE+ ++ R + A D+ Sbjct: 270 VAQAAYDTAVA-ALERRPE-----PPQAAALTLVAEIDSRLYALRATAGSALTAADALSA 323 Query: 347 ---------GRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAK 395 GR+ + AK +A ++ +D + ++GG + +P+ +L+RD + Sbjct: 324 DLSGDMDERGRQMMRHFQCAKLAVNRLAPEIVSDCLSLVGGASYTAGHPLARLLRDVQ 381 >4XVX-A nrPDB Length = 389 Score = 65.5 bits (158), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 69/281 (24%), Positives = 123/281 (43%), Gaps = 21/281 (7%) Query: 142 KKKYLGRMTEEPLMCA--YCV--TEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGK 197 K YL + ++ + A C+ +E GSD+ ++T+ + + + G K +++ Sbjct: 101 KSDYLRDICDQAIRGAAVLCIGASEESGGSDLQIVETEIRSRDGGFEVRGVKKFVSLSPI 160 Query: 198 ANWYFLLARS-DPDPKA----PANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVF 252 A+ ++ARS D DP + A A V TP ++G L+ C DT Sbjct: 161 ADHIMVVARSVDHDPTSRHGNVAVVAVPAAQVSVQTPYRKVGAGPLDTAAVCIDT----- 215 Query: 253 EDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKL 312 VP + ++ G G R +A QRA+ + R+ FG+ Sbjct: 216 ---WVPADALVARAGTGLAAISWGLAHERMSIAGQIAASCQRAIGITLARMMSRRQFGQT 272 Query: 313 LVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDA 372 L EHQA+ +A++ +V+L R + A + GR A+ K A + ++ ++ Sbjct: 273 LFEHQALRLRMADLQARVDLLRYALHGIA---EQGRLELRTAAAVKVTAARLGEEVISEC 329 Query: 373 VQILGGNGFNT-EYPVEKLMRDAKIYQIYEGTSQIQRLIVA 412 + I GG G+ E + K RD K+ ++ GT ++ +VA Sbjct: 330 MHIFGGAGYLVDETTLGKWWRDMKLARVGGGTDEVLWELVA 370 >4Y9J-A nrPDB Length = 593 Score = 59.3 bits (142), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 79/329 (24%), Positives = 144/329 (43%), Gaps = 29/329 (8%) Query: 105 ACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPG 164 A L+S +A V+T N G+ + D+ + R + +TE Sbjct: 139 AGLVSCPMAMTDGAVKTLTSLNLYGKHKLATEAVDRLR----SRDPSKAWTSGQWMTEKK 194 Query: 165 AGSDVAG-IKTKA-EKKGDEYIINGQKMWITNGGKANWYFLLAR-SDPDPKA-PANKAFT 220 GSDVAG T A + D Y ++G K W ++ A+ LAR D D A ++ + Sbjct: 195 GGSDVAGGCDTYAVQIDKDTYRLHGYK-WFSSAVDADVALTLARIVDSDGNALEGSRGLS 253 Query: 221 GFIVE-----ADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGD-GAGFKVAM 274 F+++ + GIQ+ R + +G + T ++ + + IGD G G Sbjct: 254 LFLLKIRDESGNLNGIQMVRLKNKLGTKQLPTAELLLDGAIAER----IGDQGRGVAGIS 309 Query: 275 GAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELAR 334 + TR A ++G +R + A Y+ +R FG+ + + LA+M + + Sbjct: 310 NMLNITRIHNAVASLGYMRRIISLARDYSTKRVVFGQTQSKWPLHTTTLAKMEVDTRGSM 369 Query: 335 MSYQRAAWEV---DSGRRNTYYA-------SIAKAFAGDIANQLATDAVQILGGNGFNTE 384 + AA + ++G+ + A + K +AG A + ++ ++ GG G+ + Sbjct: 370 LLLFEAARLLGLSEAGKSSDVEAMMLRLITPVLKLYAGKQAVPMVSEGIECFGGQGYMED 429 Query: 385 YPVEKLMRDAKIYQIYEGTSQIQRLIVAR 413 + L+RDA++ I+EGT+ + L V R Sbjct: 430 TGLPTLLRDAQVTPIWEGTTNVLSLDVLR 458 >4X28-D nrPDB Length = 373 Score = 58.2 bits (139), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 86/389 (22%), Positives = 155/389 (39%), Gaps = 73/389 (18%) Query: 43 EQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGT 102 E Q+E ++F RE L R+ + G++++ PE+ GG G G Sbjct: 27 EHQRELDKLEQRFDRE------------------LWRKLIDAGILSSAAPESLGGDGFGV 68 Query: 103 FDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKY-LGRMTEEPLMCAYCVT 161 + + L + V +E L + G+ + ++ + + ++ + ++ Sbjct: 69 LEQVAVLVALGHQLAAVPY-LESVVLAAGALARFGSPELQQGWGVSAVSGDRILTVALDG 127 Query: 162 EPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTG 221 E G G +A G Y + G + + G A+ + + A +D Sbjct: 128 EMGEG------PVQAAGTGHGYRLTGTRTQVGYGPVADAFLVPAETDSGAAV-------- 173 Query: 222 FIVEADTPGI-----------QIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGF 270 F+V A PG+ +G ELN G + R + DV V + Sbjct: 174 FLVAAGDPGVAVTALATTGLGSVGHLELN-GAKVDAARRVGGTDVAV------------W 220 Query: 271 KVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKV 330 + +T A +G+ +R L +YA R+ F + + QA+ LA+ + V Sbjct: 221 LGTLSTLSRT-----AFQLGVLERGLQMTAEYARTREQFDRPIGSFQAVGQRLADGYIDV 275 Query: 331 ELARMSYQRAAWEV--DS--GRRNTYYASIAKAFAG----DIANQLATDAVQILGGNGFN 382 + R++ +AAW V DS R A I A AG + +++A V + GG G + Sbjct: 276 KGLRLTLTQAAWRVAEDSLASRECPQPADIDVATAGFWAAEAGHRVAHTIVHVHGGVGVD 335 Query: 383 TEYPVEKLMRDAKIYQIYEG--TSQIQRL 409 T++PV + AK + G T Q++R+ Sbjct: 336 TDHPVHRYFLAAKQTEFALGGATGQLRRI 364 >3MXL-A nrPDB Length = 395 Score = 57.8 bits (138), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 85/353 (24%), Positives = 142/353 (40%), Gaps = 34/353 (9%) Query: 64 AAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLG-TFDACLISEELAYGCTGVQTA 122 AA+ D+TG +PV + +LGLM +P GGLGL +D LA TA Sbjct: 31 AADRDRTGTFPVEAFEQFAKLGLMGATVPAELGGLGLTRLYDVATALMRLAE--ADASTA 88 Query: 123 IEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMC------AYCVTEPGAGSDVAGIKTKA 176 + + + + Q + M E L A C GA D G+ T+ Sbjct: 89 LAWHVQLSRGLTLTYEWQHGTPPVRAMAERLLRAMAEGEAAVC----GALKDAPGVVTEL 144 Query: 177 EKKG-DEYIINGQKMWITNGGKANWYFLLA-RSDPDPKAPANKAFTGF-IVEADTPGIQI 233 G ++++G+K+ ++ A +F+ A R D D F +V D PG+ + Sbjct: 145 HSDGAGGWLLSGRKVLVSMAPIATHFFVHAQRRDDD-----GSVFLAVPVVHRDAPGLTV 199 Query: 234 GRKELNMGQRCSDTRGIVFEDVKVPKENVL-IGDGAGFKVAMGAFDKTRPVVAAGA-VGL 291 +G R S T +VF+ V + +L G + A+ A + G G+ Sbjct: 200 LDNWDGLGMRASGTLEVVFDRCPVRADELLERGPVGARRDAVLAGQTVSSITMLGIYAGI 259 Query: 292 AQRALDEATKYALER----KTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEV--- 344 AQ A D A + R + + LV + L + V A + A+ ++ Sbjct: 260 AQAARDIAVGFCAGRGGEPRAGARALV--AGLDTRLYALRTTVGAALTNADAASVDLSGD 317 Query: 345 --DSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAK 395 + GRR AK ++A + D + ++GG + +P+ +L RD + Sbjct: 318 PDERGRRMMTPFQYAKMTVNELAPAVVDDCLSLVGGLAYTAGHPLSRLYRDVR 370 >1W07-A nrPDB Length = 659 Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 52/204 (25%), Positives = 91/204 (44%), Gaps = 33/204 (16%) Query: 137 GNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKA--EKKGDEYIIN-----GQK 189 G ++Q+KK+L + ++ Y TE G GS+V G++T A + K DE++I+ K Sbjct: 114 GTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATLDPKTDEFVIHTPTQTASK 173 Query: 190 MWITNGGKANWYFLL-ARSDPDPKAPANKAFTGFIVE-------ADTPGIQIGRKELNMG 241 W GK + + ++ AR + K + GFIV+ + P I +G MG Sbjct: 174 WWPGGLGKVSTHAVVYARLITNGK---DYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMG 230 Query: 242 Q---RCSDTRGIVFEDVKVPKENVL------------IGDGAGFKVAMGAFDKTRPVVAA 286 D ++F+ V++P++ +L + ++ G R + A Sbjct: 231 NGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVA 290 Query: 287 GAVGLAQRALDEATKYALERKTFG 310 A RA+ AT+Y+ R+ FG Sbjct: 291 DASNALSRAVCIATRYSAVRRQFG 314 >2FON-A nrPDB Length = 683 Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 67/279 (24%), Positives = 114/279 (40%), Gaps = 55/279 (19%) Query: 137 GNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKA--EKKGDEYIIN-----GQK 189 G D+Q++K+L + ++ Y TE G GS+V G++T A + + DE++I+ K Sbjct: 133 GTDKQQEKWLPLAYKMQIIGCYAQTELGHGSNVQGLETTATFDPQTDEFVIHSPTLTSSK 192 Query: 190 MWITNGGKANWYFLL-ARSDPDPKAPANKAFTGFIVEADT-------PGIQIGRKELNMG 241 W GK + + ++ AR D K + GFIV+ + PG+ +G + G Sbjct: 193 WWPGGLGKVSTHAVVYARLITDGK---DYGVNGFIVQLRSLEDHKPLPGVTVGDIGMKFG 249 Query: 242 Q---RCSDTRGIVFEDVKVPKENVL------------IGDGAGFKVAMGAFDKTRPVVAA 286 D + F+ V++P++ +L + ++ G R + A Sbjct: 250 NGAYNSMDNGVLSFDHVRIPRDQMLMRVSQVTKEGKYVQSDIPRQLLYGTMVYVRQSIVA 309 Query: 287 GAVGLAQRALDEATKYALERKTFGKLL--VEHQAISFMLAEMAMKVELARMSYQRAAWEV 344 A RA+ AT+Y+ R+ FG E Q I + + + LA Sbjct: 310 DASLAMSRAVCIATRYSAVRRQFGSQNGGQETQVIDYKTQQNRLFPLLA----------- 358 Query: 345 DSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNT 383 ++ A F G+ L TD Q L N F+T Sbjct: 359 ---------SAYAFRFVGEWLKWLYTDVTQRLAANDFST 388 >4ZYJ-A nrPDB Length = 425 Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 86/380 (22%), Positives = 143/380 (37%), Gaps = 52/380 (13%) Query: 66 EYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTF-DACLISEELAYGCTGVQTAIE 124 + D+ PV L R + G++ +PE+ GGLG+ + D L +A GV A+ Sbjct: 66 DNDREATLPVHLFDRMRKEGVLGATVPEDLGGLGVHSLHDVALALARIAGRDAGVALALH 125 Query: 125 -----GNSL------GQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIK 173 G +L G D ++ G E ++C GA DV G Sbjct: 126 MQFSRGLTLDFEWRHGAPSTRPLAEDLLRQMGAG----EAVIC-------GAVKDVRGTT 174 Query: 174 TKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQI 233 Y +NG+K ++ G A Y + R + +A A +V TPG+ + Sbjct: 175 VLTRATDGSYRLNGRKTLVSMAGIATHYVVSTRLE---EAGAPVRLAAPVVARTTPGLTV 231 Query: 234 GRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGA--VGL 291 MG R S + IVF+ V ++ VL G + +T +A VG+ Sbjct: 232 LDNWDGMGMRSSGSVDIVFDGCPVDRDRVLPRGEPGVRDDAALAGQTVSSIAMLGIYVGI 291 Query: 292 AQR----ALDEATKY----ALERKTF----GKLLVEHQAISFMLAEMAMKVELARMSYQR 339 A+ AL E + A R T +L H A++ L R++ Sbjct: 292 AEAARRIALTELRRRGGAPAGVRTTVAEIDARLFALHTAVASALTTA------DRLADDL 345 Query: 340 AAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKI--- 396 + GR AK + + D + ++GG G++ +P+ +L RD + Sbjct: 346 SGDLAARGRAMMTPFQYAKLLVNRHSVGVVDDCLMLVGGAGYSNSHPLARLYRDVRAGGF 405 Query: 397 ---YQIYEGTSQIQRLIVAR 413 Y +G + + + R Sbjct: 406 MHPYNFTDGVDYLSEVALGR 425 >5YS9-A nrPDB Length = 708 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 50/176 (28%), Positives = 78/176 (44%), Gaps = 23/176 (13%) Query: 158 YCVTEPGAGSDVAGIKTKAE--KKGDEYIIN-----GQKMWITNGG-KANWYFLLARSDP 209 + +TE G GS+VAG++T A + DE+IIN K WI A AR Sbjct: 160 FAMTELGHGSNVAGLETTATYIQDTDEFIINTPNTGATKWWIGGAAHSATHTACFARLLV 219 Query: 210 DPKAPANKAFTGFIVEADT----PGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVL-- 263 D K K F + + + PGI +G MG+ D I F +V++P++N+L Sbjct: 220 DGKDYGVKIFVVQLRDVSSHSLMPGIALGDIGKKMGRDAIDNGWIQFTNVRIPRQNMLMK 279 Query: 264 ---------IGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFG 310 + ++ GA R + A + ++QR + A +YA R+ FG Sbjct: 280 YAKVSSTGKVSQPPLAQLTYGALIGGRVTMIADSFFVSQRFITIALRYACVRRQFG 335 >5K3G-A nrPDB Length = 684 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 52/214 (24%), Positives = 92/214 (42%), Gaps = 29/214 (13%) Query: 123 IEGNSLGQ-----MPIIIA-GNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKA 176 IEGN + +P + A +D+Q+ K+L R ++ Y TE G G+++ ++T A Sbjct: 108 IEGNPMALHGVMFIPALNAQASDEQQAKWLIRALRREIIGTYAQTEMGHGTNLQNLETTA 167 Query: 177 --EKKGDEYIINGQKM-----WITNGGK-ANWYFLLARSDPDPKAPANKAFTGFIVEADT 228 + E++++ K+ W N GK +N+ ++A K F + + T Sbjct: 168 TYDIGTQEFVLHTPKITALKWWPGNLGKSSNYAVVVAHMYIKGKNFGPHTFMVPLRDEKT 227 Query: 229 ----PGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLI------GDGAGF-----KVA 273 PGI IG M D + F + ++P+ N+L+ DG K+ Sbjct: 228 HKPLPGITIGDIGPKMAYNIVDNGFLGFNNYRIPRTNLLMRHTKVEADGTYIKPPHAKIN 287 Query: 274 MGAFDKTRPVVAAGAVGLAQRALDEATKYALERK 307 A R + G + AL+ AT+Y+ R+ Sbjct: 288 YSAMVHVRSYMLTGQAIMLSYALNIATRYSAVRR 321 >5Y9D-A nrPDB Length = 709 Score = 44.3 bits (103), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 45/176 (25%), Positives = 79/176 (44%), Gaps = 23/176 (13%) Query: 158 YCVTEPGAGSDVAGIKTKA--EKKGDEYIIN-----GQKMWITNGGKANWYFL-LARSDP 209 + +TE G GS++ G++T A ++ D++IIN K WI + + + A+ Sbjct: 166 FAMTELGHGSNLKGLETTATYDQDSDQFIINTPHIGATKWWIGGAAHTSTHCVCFAKLIV 225 Query: 210 DPKAPANKAFTGFIVEADTP----GIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLI- 264 K + F + G+ IG MG+ D I F +V++P++N+L+ Sbjct: 226 HGKDYGTRNFVVPLRNVHDHSLKVGVSIGDIGKKMGRDGVDNGWIQFTNVRIPRQNMLMR 285 Query: 265 -----GDGAGFKVAM-----GAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFG 310 G K A+ GA + R + A + +++R L A +YA R+ FG Sbjct: 286 YAKVSDTGVVTKPALDQLTYGALIRGRVSMIADSFHVSKRFLTIALRYACVRRQFG 341 >5XDD-A nrPDB Length = 414 Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust. Identities = 67/292 (22%), Positives = 112/292 (38%), Gaps = 28/292 (9%) Query: 21 RSQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRR 80 R+ H ++ RE TE K F+ T R+ R P AE D IRR Sbjct: 2 RTIHANSSAVREDHRALDVA-TELAKTFRVTVRERERAGGTP-KAERDA--------IRR 51 Query: 81 AWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQ 140 + GL+ I + GGLG E+A + + + + + + Sbjct: 52 S---GLLTLLISKERGGLGESWPTVYEAIAEIASADASLGHLFGYHFSNFAYVDLFASPE 108 Query: 141 QKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGD-EYIINGQKMWITNGGKAN 199 QK ++ + E +E A V + A D Y ING K + + A+ Sbjct: 109 QKARWYPQAVRERWFLGNASSENNA--HVLDWRVTATPLPDGSYEINGTKAFCSGSADAD 166 Query: 200 WYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKV-P 258 + A + DP + ++ +D G+Q+ ++G R +D+ + F V V P Sbjct: 167 RLLVFAVTSRDPNG--DGRIVAALIPSDRAGVQVNGDWDSLGMRQTDSGSVTFSGVVVYP 224 Query: 259 KENVLIGDGAGFKVAMGAFDK-------TRPVVAAGAVGLAQRALDEATKYA 303 E L+G A + K T+ + +G+A+ AL+EA Y+ Sbjct: 225 DE--LLGTPGQVTDAFASGSKPSLWTPITQLIFTHLYLGIARGALEEAAHYS 274 >1IS2-A nrPDB Length = 661 Score = 36.6 bits (83), Expect = 0.022, Method: Compositional matrix adjust. Identities = 49/202 (24%), Positives = 84/202 (41%), Gaps = 26/202 (12%) Query: 131 MPIII--AGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKA--EKKGDEYIIN 186 +P ++ A +QQ++ ++ E + Y TE G G+ + G++T A + K E+I+N Sbjct: 108 LPTLLHQATAEQQERFFMPAWNLE-ITGTYAQTEMGHGTHLRGLETTATYDPKTQEFILN 166 Query: 187 GQ-----KMWITNGGK-ANWYFLLARSDPDPKAPANKAFTGFIVEADT----PGIQIGRK 236 K W GK +N +LA+ + AF I E T PGI +G Sbjct: 167 SPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDI 226 Query: 237 ELNMGQRCSDTRGIVFEDVKVPKENVLIG------DGA-----GFKVAMGAFDKTRPVVA 285 G D + ++ ++P+EN+L+ DG K+ G R + Sbjct: 227 GPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLV 286 Query: 286 AGAVGLAQRALDEATKYALERK 307 A +A A +Y+ R+ Sbjct: 287 GNAAQSLSKACTIAIRYSAVRR 308 >4D1J-A nrPDB Length = 540 Score = 33.1 bits (74), Expect = 0.24, Method: Compositional matrix adjust. Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 3/65 (4%) Query: 282 PVVAAGAVGLAQRALDEA--TKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQR 339 P + G +G + +D+ T Y L K + +E A + L M+ E AR+SYQ Sbjct: 327 PTLGKGGIGFSPFGMDDTDYTNYPLGAKVYNDETIEQFAQVYRLVNPMMR-EWARLSYQG 385 Query: 340 AAWEV 344 W V Sbjct: 386 QVWGV 390 >2R60-A nrPDB Length = 499 Score = 32.3 bits (72), Expect = 0.45, Method: Compositional matrix adjust. Identities = 19/60 (31%), Positives = 27/60 (45%) Query: 293 QRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTY 352 Q D A Y E FG LV + +S LAEM ++V++ + W SG + Y Sbjct: 16 QGNFDPADSYWTEHPDFGGQLVYVKEVSLALAEMGVQVDIITRRIKDENWPEFSGEIDYY 75 >6NCL-d0 nrPDB Length = 437 Score = 31.6 bits (70), Expect = 0.67, Method: Compositional matrix adjust. Identities = 13/35 (37%), Positives = 21/35 (60%) Query: 362 GDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKI 396 GD+ + + V GGNG T YP E+L++D ++ Sbjct: 64 GDLITDIVVEFVLTKGGNGGTTYYPAEELLQDVEL 98 >5K3J-A nrPDB Length = 674 Score = 31.6 bits (70), Expect = 0.69, Method: Compositional matrix adjust. Identities = 32/142 (22%), Positives = 63/142 (44%), Gaps = 16/142 (11%) Query: 137 GNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKA--EKKGDEYIIN-----GQK 189 +D+Q++K+L R ++ Y TE G GS++ ++T A + E++++ K Sbjct: 126 ASDEQQEKWLERARRREIIGCYAQTELGHGSNLRNLETTAVYDIASQEFVLHTPTTTALK 185 Query: 190 MWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVE-----ADTP--GIQIGRKELNMGQ 242 W GK+ Y L+ + F F+V+ P G+ +G M Sbjct: 186 WWPGALGKSCNYALVVAELIIKRNNYGPHF--FMVQLRDEKTHIPLKGVTVGDIGPKMNF 243 Query: 243 RCSDTRGIVFEDVKVPKENVLI 264 +D + +++VP+ N+L+ Sbjct: 244 NAADNGYLGLNNLRVPRTNLLM 265 >2RFQ-A nrPDB Length = 394 Score = 29.6 bits (65), Expect = 2.3, Method: Compositional matrix adjust. Identities = 56/238 (23%), Positives = 85/238 (35%), Gaps = 34/238 (14%) Query: 83 ELGLMNTHIPENCGGLGLGT--FDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQ 140 E G PE GG F + + A G TG ++I G + + + Q Sbjct: 46 ETGFFRLLQPEQWGGYQADPVLFYSAVRKIASACGSTGWVSSIIGVHNWHLALF---SQQ 102 Query: 141 QKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANW 200 ++ G T+ + +Y GAG V G Y +NG W + A+W Sbjct: 103 AQEDVWGNDTDVRISSSYAPM--GAGQVVDG----------GYTVNGAWAWSSGCDHASW 150 Query: 201 YFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKE 260 L P K F F++ + +I +G R + + +V EDV VP Sbjct: 151 AVL---GGPVIKDGRPVDFVSFLIPRED--YRIDDVWNVVGLRGTGSNTVVVEDVFVPTH 205 Query: 261 NVLIGDGAGFKVAMGAFDKTRPV------------VAAGAVGLAQRALDEATKYALER 306 VL A G T PV ++A VG+A A D ++ +R Sbjct: 206 RVLSFKAMSNLTAPGLERNTAPVYKMPWGTIHPTTISAPIVGMAYGAYDAHVEHQGKR 263 >4ZNZ-A nrPDB Length = 220 Score = 29.3 bits (64), Expect = 3.2, Method: Compositional matrix adjust. Identities = 26/88 (29%), Positives = 37/88 (42%), Gaps = 6/88 (6%) Query: 114 YGCTGVQTAIEGNSLGQMP---IIIAGNDQQKKKYLGRMTEE---PLMCAYCVTEPGAGS 167 YGC GVQ A+E LG + + I + LG M +E +C V E Sbjct: 99 YGCGGVQAAVENPELGLINNWLLHIRDIWFKHSSLLGEMPQERRLDTLCELNVMEQVYNL 158 Query: 168 DVAGIKTKAEKKGDEYIINGQKMWITNG 195 + I A K+G + I+G I +G Sbjct: 159 GHSTIMQSAWKRGQKVTIHGWAYGIHDG 186 >5W5B-A nrPDB Length = 236 Score = 28.9 bits (63), Expect = 4.6, Method: Compositional matrix adjust. Identities = 17/43 (39%), Positives = 27/43 (62%), Gaps = 1/43 (2%) Query: 294 RALDEATKYALERKTFGKLLVEHQAISFM-LAEMAMKVELARM 335 RAL +AT L+R+ F +LL H AI+ L+ +A +V A++ Sbjct: 116 RALTQATCLFLDRQAFERLLATHPAIARRWLSSVAQRVSTAQI 158 >4E20-A nrPDB Length = 290 Score = 28.1 bits (61), Expect = 6.5, Method: Compositional matrix adjust. Identities = 20/70 (28%), Positives = 30/70 (42%), Gaps = 1/70 (1%) Query: 45 QKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFD 104 Q+E + R E I+ + GE V L+ LG + ++P +C GL Sbjct: 58 QREIE-ILRTLYHEHIVKYKGCCEDQGEKSVQLVMEYVPLGSLRDYLPRHCVGLAQLLLF 116 Query: 105 ACLISEELAY 114 A I E +AY Sbjct: 117 AQQICEGMAY 126 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2A1T-A nrPDB 581 e-166 3MDE-A nrPDB 503 e-143 1JQI-A nrPDB 480 e-136 4L1F-A nrPDB 475 e-134 1UKW-A nrPDB 474 e-134 5OL2-C nrPDB 473 e-134 4N5F-A nrPDB 469 e-132 2VIG-A nrPDB 468 e-132 5LNX-A nrPDB 466 e-132 4U83-A nrPDB 451 e-127 4M9A-A nrPDB 448 e-126 6FAH-C nrPDB 444 e-125 1BUC-A nrPDB 440 e-124 3PFD-A nrPDB 437 e-123 4O5M-A nrPDB 437 e-123 1IVH-A nrPDB 433 e-122 4KTO-A nrPDB 429 e-121 2JIF-A nrPDB 425 e-119 1RX0-A nrPDB 424 e-119 4IV6-A nrPDB 420 e-118 2PG0-A nrPDB 413 e-116 2DVL-A nrPDB 410 e-115 4IRN-A nrPDB 407 e-114 3MPI-A nrPDB 399 e-112 3GNC-A nrPDB 398 e-111 3NF4-A nrPDB 398 e-111 2CX9-A nrPDB 393 e-109 2Z1Q-A nrPDB 385 e-107 3SF6-A nrPDB 382 e-106 2EBA-A nrPDB 380 e-106 3OWA-A nrPDB 380 e-106 6ES9-A nrPDB 373 e-104 4W9U-A nrPDB 373 e-103 1SIR-A nrPDB 371 e-103 5ZW7-A nrPDB 371 e-103 3R7K-A nrPDB 371 e-103 3B96-A nrPDB 364 e-101 2IX5-A nrPDB 362 e-100 3SWO-A nrPDB 361 e-100 6CY8-B nrPDB 360 e-100 5IDU-A nrPDB 360 e-100 3P4T-A nrPDB 354 4e-98 5AHS-A nrPDB 348 3e-96 5JSC-A nrPDB 330 7e-91 4HR3-A nrPDB 312 2e-85 2WBI-A nrPDB 298 2e-81 4RM7-A nrPDB 279 1e-75 1R2J-A nrPDB 274 6e-74 4X28-A nrPDB 273 9e-74 2C12-A nrPDB 268 4e-72 3MKH-A nrPDB 251 4e-67 5GJ7-A nrPDB 236 1e-62 3M9V-A nrPDB 226 1e-59 4ZYJ-A nrPDB 219 2e-57 4Y9J-A nrPDB 216 1e-56 3U33-A nrPDB 214 5e-56 5EZ3-A nrPDB 212 3e-55 3MXL-A nrPDB 210 6e-55 4X28-D nrPDB 208 5e-54 4XVX-A nrPDB 198 5e-51 5YS9-A nrPDB 190 1e-48 5Y9D-A nrPDB 189 2e-48 2FON-A nrPDB 184 5e-47 1W07-A nrPDB 181 6e-46 5K3G-A nrPDB 160 1e-39 Sequences not found previously or not previously below threshold: 1IS2-A nrPDB 156 1e-38 5K3J-A nrPDB 140 2e-33 5XDD-A nrPDB 139 2e-33 4JEK-A nrPDB 137 9e-33 2JBS-A nrPDB 99 3e-21 2RFQ-A nrPDB 96 3e-20 3AFF-A nrPDB 94 1e-19 5LVW-A nrPDB 90 2e-18 2OR0-A nrPDB 72 5e-13 3HWC-A nrPDB 41 0.001 2YYI-A nrPDB 39 0.003 1U8V-A nrPDB 35 0.053 4G5E-A nrPDB 34 0.12 4JKZ-A nrPDB 31 1.0 5VWM-A nrPDB 31 1.3 4B3K-A nrPDB 30 1.6 6C9C-A nrPDB 30 1.6 3DR5-A nrPDB 30 2.0 2YXE-A nrPDB 30 2.5 2Q3R-A nrPDB 30 2.6 6J5G-A nrPDB 30 2.7 6B1B-A nrPDB 30 3.1 4S1V-D nrPDB 29 3.8 4U3T-A nrPDB 29 4.1 4QNW-A nrPDB 29 4.7 2GG4-A nrPDB 29 4.8 5KSH-A nrPDB 28 6.1 >2A1T-A nrPDB Length = 421 Score = 581 bits (1498), Expect = e-166, Method: Composition-based stats. Identities = 421/421 (100%), Positives = 421/421 (100%) Query: 1 MAAGFGRCCRVLRSISRFHWRSQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEI 60 MAAGFGRCCRVLRSISRFHWRSQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEI Sbjct: 1 MAAGFGRCCRVLRSISRFHWRSQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEI 60 Query: 61 IPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQ 120 IPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQ Sbjct: 61 IPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQ 120 Query: 121 TAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKG 180 TAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKG Sbjct: 121 TAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKG 180 Query: 181 DEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNM 240 DEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNM Sbjct: 181 DEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNM 240 Query: 241 GQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEAT 300 GQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEAT Sbjct: 241 GQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEAT 300 Query: 301 KYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAF 360 KYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAF Sbjct: 301 KYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAF 360 Query: 361 AGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDKYK 420 AGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDKYK Sbjct: 361 AGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDKYK 420 Query: 421 N 421 N Sbjct: 421 N 421 >3MDE-A nrPDB Length = 385 Score = 503 bits (1296), Expect = e-143, Method: Composition-based stats. Identities = 344/385 (89%), Positives = 370/385 (96%) Query: 36 GFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENC 95 GFSFE TEQQKEFQATARKFAREEIIPVAAEYD+TGEYPVPL++RAWELGLMNTHIPE+ Sbjct: 1 GFSFELTEQQKEFQATARKFAREEIIPVAAEYDRTGEYPVPLLKRAWELGLMNTHIPESF 60 Query: 96 GGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLM 155 GGLGLG D+CLI+EELAYGCTGVQTAIE N+LGQ+P+II GN QQ+KKYLGRMTEEPLM Sbjct: 61 GGLGLGIIDSCLITEELAYGCTGVQTAIEANTLGQVPLIIGGNYQQQKKYLGRMTEEPLM 120 Query: 156 CAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA 215 CAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA Sbjct: 121 CAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA 180 Query: 216 NKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMG 275 +KAFTGFIVEADTPG+QIGRKE+NMGQRCSDTRGIVFEDV+VPKENVL G+GAGFK+AMG Sbjct: 181 SKAFTGFIVEADTPGVQIGRKEINMGQRCSDTRGIVFEDVRVPKENVLTGEGAGFKIAMG 240 Query: 276 AFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARM 335 FDKTRP VAAGAVGLAQRALDEATKYALERKTFGKLL EHQ ISF+LA+MAMKVELAR+ Sbjct: 241 TFDKTRPPVAAGAVGLAQRALDEATKYALERKTFGKLLAEHQGISFLLADMAMKVELARL 300 Query: 336 SYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAK 395 SYQRAAWE+DSGRRNTYYASIAKA+A DIANQLATDAVQ+ GGNGFNTEYPVEKLMRDAK Sbjct: 301 SYQRAAWEIDSGRRNTYYASIAKAYAADIANQLATDAVQVFGGNGFNTEYPVEKLMRDAK 360 Query: 396 IYQIYEGTSQIQRLIVAREHIDKYK 420 IYQIYEGT+QIQR+I+AREHI +YK Sbjct: 361 IYQIYEGTAQIQRIIIAREHIGRYK 385 >1JQI-A nrPDB Length = 388 Score = 480 bits (1235), Expect = e-136, Method: Composition-based stats. Identities = 148/386 (38%), Positives = 227/386 (58%), Gaps = 4/386 (1%) Query: 37 FSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCG 96 S E E + + T R FA +E++P+AA+ DK +P +++ ELGL+ +PE Sbjct: 6 QSVELPETHQMLRQTCRDFAEKELVPIAAQLDKEHLFPTSQVKKMGELGLLAMDVPEELS 65 Query: 97 GLGLGTFDACLISEELAYGCTGVQTAIE-GNSLGQMPIIIAGNDQQKKKYLGRMTEEPLM 155 G GL + EE++ GC + NSL PI+ G+ QQK++++ T + Sbjct: 66 GAGLDYLAYSIALEEISRGCASTGVIMSVNNSLYLGPILKFGSSQQKQQWITPFTNGDKI 125 Query: 156 CAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA 215 + ++EPG GSD T A ++GD +++NG K WITN +A+ + A +D ++ Sbjct: 126 GCFALSEPGNGSDAGAASTTAREEGDSWVLNGTKAWITNSWEASATVVFASTD---RSRQ 182 Query: 216 NKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMG 275 NK + F+V TPG+ +G+KE +G R S T ++FED ++PKEN+L G GFK+AM Sbjct: 183 NKGISAFLVPMPTPGLTLGKKEDKLGIRASSTANLIFEDCRIPKENLLGEPGMGFKIAMQ 242 Query: 276 AFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARM 335 D R +A+ A+G+AQ +LD A KYA R FG L + Q I F LA+MA+ +E AR+ Sbjct: 243 TLDMGRIGIASQALGIAQASLDCAVKYAENRHAFGAPLTKLQNIQFKLADMALALESARL 302 Query: 336 SYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAK 395 RAA D+ + T +++AK A + A ++ A+QILGG G+ TE P E+ RDA+ Sbjct: 303 LTWRAAMLKDNKKPFTKESAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERYYRDAR 362 Query: 396 IYQIYEGTSQIQRLIVAREHIDKYKN 421 I +IYEGTS+IQRL++A + Y++ Sbjct: 363 ITEIYEGTSEIQRLVIAGHLLRSYRS 388 >4L1F-A nrPDB Length = 383 Score = 475 bits (1223), Expect = e-134, Method: Composition-based stats. Identities = 155/385 (40%), Positives = 225/385 (58%), Gaps = 4/385 (1%) Query: 37 FSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCG 96 F TE Q+ + A +FA + + P E DK + LI + E G PE G Sbjct: 1 MDFNLTEDQQMIKDMAAEFAEKFLAPTVEERDKAHIWDRKLIDKMGEAGFCGICFPEEYG 60 Query: 97 GLGLGTFDACLISEELAYGCTGVQTAIEGN-SLGQMPIIIAGNDQQKKKYLGRMTEEPLM 155 G+GL L EEL+ G + N SL PI + G ++QK+KYL + E + Sbjct: 61 GMGLDVLSYILAVEELSKVDDGTGITLSANVSLCATPIYMFGTEEQKQKYLAPIAEGTHV 120 Query: 156 CAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA 215 A+ +TEP AG+D + +T A KGD+YI+NG K++ITNG +A+ Y + A +D K+ Sbjct: 121 GAFGLTEPSAGTDASAQQTTAVLKGDKYILNGSKIFITNGKEADTYVVFAMTD---KSQG 177 Query: 216 NKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMG 275 + FI+E PG + G+ E MG S T ++FED +VPKEN+L +G GFK+AM Sbjct: 178 VHGISAFILEKGMPGFRFGKIEDKMGGHTSITAELIFEDCEVPKENLLGKEGEGFKIAME 237 Query: 276 AFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARM 335 D R VAA A+G+A+ AL A KY+ ER+ FG+ + + QA+ FM+A+MA K+E AR Sbjct: 238 TLDGGRIGVAAQALGIAEGALAAAVKYSKEREQFGRSISKFQALQFMMADMATKIEAARY 297 Query: 336 SYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAK 395 AA + G+ + A++AK FA D+A ++ TDAVQI GG G+ +YP E+ MR+AK Sbjct: 298 LVYHAAMLKNEGKPYSEAAAMAKCFASDVAMEVTTDAVQIFGGYGYTVDYPAERYMRNAK 357 Query: 396 IYQIYEGTSQIQRLIVAREHIDKYK 420 I QIYEGT+Q+ R++ +R + K Sbjct: 358 ITQIYEGTNQVMRIVTSRALLRDKK 382 >1UKW-A nrPDB Length = 379 Score = 474 bits (1221), Expect = e-134, Method: Composition-based stats. Identities = 183/382 (47%), Positives = 257/382 (67%), Gaps = 3/382 (0%) Query: 37 FSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCG 96 F TE+Q++ QA AR+FA+E I+PVA EYD+ E P P+I + E+GL+N IPE G Sbjct: 1 IDFSLTEEQRQLQALARRFAKEVILPVAQEYDEKEEVPWPVIEKLHEVGLLNAIIPEEYG 60 Query: 97 GLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMC 156 G+GL D ++ EELAY C G+ T + LG P+++AG ++QK+++L +TE+P + Sbjct: 61 GMGLKMLDEVIVGEELAYACMGIYTIPMASDLGITPVLLAGTEEQKERFLRPLTEKPALA 120 Query: 157 AYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPAN 216 A+ ++EPG GSD A +KT+A ++GD Y++NG KMWI+NGG+A W + A +P+ + Sbjct: 121 AFALSEPGNGSDAAALKTRAIRQGDHYVLNGTKMWISNGGEAEWVVVFATVNPE---LRH 177 Query: 217 KAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGA 276 K +VE TPG + + MGQR S T +VFEDVKVP EN L +G GFK+AM Sbjct: 178 KGVVALVVERGTPGFKAIKIHGKMGQRASGTYELVFEDVKVPVENRLGEEGEGFKIAMQT 237 Query: 277 FDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMS 336 +KTR VAAG+VG+A+RALDEA KYA ER+ FG+ + QAI F L +M + +E ARM Sbjct: 238 LNKTRIPVAAGSVGVARRALDEARKYAKEREAFGEPIANFQAIQFKLVDMLIGIETARMY 297 Query: 337 YQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKI 396 AAW D G + + ++IAKA+A +IA + A A+QI GG G+ E+PVEKL+RD K+ Sbjct: 298 TYYAAWLADQGLPHAHASAIAKAYASEIAFEAANQAIQIHGGYGYVREFPVEKLLRDVKL 357 Query: 397 YQIYEGTSQIQRLIVAREHIDK 418 QIYEGT++IQRLI+AR + Sbjct: 358 NQIYEGTNEIQRLIIARHILAA 379 >5OL2-C nrPDB Length = 378 Score = 473 bits (1217), Expect = e-134, Method: Composition-based stats. Identities = 150/377 (39%), Positives = 223/377 (59%), Gaps = 4/377 (1%) Query: 42 TEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLG 101 +++ + + FA E+ P+A E D+ +P + + + G+M P+ GG G Sbjct: 5 SKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKMAKAGMMGIPYPKEYGGEGGD 64 Query: 102 TFDACLISEELAYGCTGVQTAIEGN-SLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCV 160 T + EEL+ C + + SLG PI GN++QK+K+L + + A+ + Sbjct: 65 TVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGNEEQKQKFLRPLASGEKLGAFGL 124 Query: 161 TEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFT 220 TEP AG+D +G +T A GDEYI+NG K++ITN + Y ++A +D K+ NK + Sbjct: 125 TEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAIAGDIYVVMAMTD---KSKGNKGIS 181 Query: 221 GFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKT 280 FIVE TPG G KE MG R S T ++FED ++PKEN+L +G GFK+AM D Sbjct: 182 AFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRIPKENLLGKEGQGFKIAMSTLDGG 241 Query: 281 RPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRA 340 R +AA A+GLAQ ALDE KY ER FG+ L + Q F LA+M +KV+ AR +A Sbjct: 242 RIGIAAQALGLAQGALDETVKYVKERVQFGRPLSKFQNTQFQLADMEVKVQAARHLVYQA 301 Query: 341 AWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIY 400 A D G+ A++AK FA + A ++ T AVQ+ GG G+ +YPVE++MRDAKI +IY Sbjct: 302 AINKDLGKPYGVEAAMAKLFAAETAMEVTTKAVQLHGGYGYTRDYPVERMMRDAKITEIY 361 Query: 401 EGTSQIQRLIVAREHID 417 EGTS++QR++++ + + Sbjct: 362 EGTSEVQRMVISGKLLK 378 >4N5F-A nrPDB Length = 385 Score = 469 bits (1206), Expect = e-132, Method: Composition-based stats. Identities = 143/380 (37%), Positives = 222/380 (58%), Gaps = 4/380 (1%) Query: 37 FSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCG 96 +TE Q+ + AR FA E + P AA++D P ++ + ELGL+ +P+ G Sbjct: 9 MDELYTEDQRMIRDAARAFATEMLAPNAAQWDHDAHLPDAIVAQLGELGLLGMIVPQELG 68 Query: 97 GLGLGTFDACLISEELAYGCTGVQTAIE-GNSLGQMPIIIAGNDQQKKKYLGRMTEEPLM 155 G L EE+A G T + NS+G PI+ G QK ++L M ++ Sbjct: 69 GSYTDYVAYALAMEEVAAGDAACATMMSVHNSVGCGPILGFGTPAQKDRWLADMAAGRVI 128 Query: 156 CAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA 215 A+C+TEP AGS+ ++T+AE + ++++NG K ++TNG +A + A +DP+ Sbjct: 129 GAFCLTEPHAGSEANNLRTRAELRDGQWVLNGAKQFVTNGQRAGVAIVFAMTDPEA---G 185 Query: 216 NKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMG 275 + + F+V DTPG +G+ E MG R SDT I FE+ +P++N+L G G K+A+ Sbjct: 186 KRGISAFLVPTDTPGFIVGKPEKKMGIRASDTCPITFENCAIPEDNLLGNRGEGLKIALS 245 Query: 276 AFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARM 335 + R +AA A+G+A+ A D+A +YA ER FGK + EHQAI LA+MA+++ AR+ Sbjct: 246 NLEGGRIGIAAQALGIARAAFDKARRYAGERVQFGKPIAEHQAIQQKLADMAVQINAARL 305 Query: 336 SYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAK 395 AA +G AS AK FA ++A ++ +DA+QI GG G+ +Y VE+ RDA+ Sbjct: 306 LVHHAAKLRTAGLPCLSEASQAKLFASEMAERVCSDAIQIHGGYGYLVDYEVERHYRDAR 365 Query: 396 IYQIYEGTSQIQRLIVAREH 415 I QIYEGTS++QR+++AR+ Sbjct: 366 ITQIYEGTSEVQRMVIARQL 385 >2VIG-A nrPDB Length = 391 Score = 468 bits (1205), Expect = e-132, Method: Composition-based stats. Identities = 146/386 (37%), Positives = 222/386 (57%), Gaps = 4/386 (1%) Query: 37 FSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCG 96 S E E + T R FA +E+ P+AA+ DK +P +++ LGL+ +PE G Sbjct: 2 QSVELPETHQMLLQTCRDFAEKELFPIAAQVDKEHLFPAAQVKKMGGLGLLAMDVPEELG 61 Query: 97 GLGLGTFDACLISEELAYGCTGVQTAIE-GNSLGQMPIIIAGNDQQKKKYLGRMTEEPLM 155 G GL + EE++ GC + NSL PI+ G+ +QK+ ++ T + Sbjct: 62 GAGLDYLAYAIAMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQKQAWVTPFTSGDKI 121 Query: 156 CAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA 215 + ++EPG GSD T A +GD +++NG K WITN +A+ + A +D +A Sbjct: 122 GCFALSEPGNGSDAGAASTTARAEGDSWVLNGTKAWITNAWEASAAVVFASTD---RALQ 178 Query: 216 NKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMG 275 NK+ + F+V TPG+ +G+KE +G R S T ++FED ++PK+++L G GFK+AM Sbjct: 179 NKSISAFLVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILGEPGMGFKIAMQ 238 Query: 276 AFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARM 335 D R +A+ A+G+AQ ALD A YA R FG L + Q I F LA+MA+ +E AR+ Sbjct: 239 TLDMGRIGIASQALGIAQTALDCAVNYAENRMAFGAPLTKLQVIQFKLADMALALESARL 298 Query: 336 SYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAK 395 RAA D+ + A++AK A + A ++ A+QILGG G+ TE P E+ RDA+ Sbjct: 299 LTWRAAMLKDNKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERHYRDAR 358 Query: 396 IYQIYEGTSQIQRLIVAREHIDKYKN 421 I +IYEGTS+IQRL++A + Y++ Sbjct: 359 ITEIYEGTSEIQRLVIAGHLLRSYRS 384 >5LNX-A nrPDB Length = 379 Score = 466 bits (1200), Expect = e-132, Method: Composition-based stats. Identities = 150/379 (39%), Positives = 224/379 (59%), Gaps = 4/379 (1%) Query: 39 FEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGL 98 T++Q + R FAR+EI P A +KT E+P LI++ + GLM +PE GG Sbjct: 1 MHVTQEQVMMRKMVRDFARKEIAPAAEIMEKTDEFPFQLIKKMGKHGLMGIPVPEQYGGA 60 Query: 99 GLGTFDACLISEELAYGCTGVQTAIEGN-SLGQMPIIIAGNDQQKKKYLGRMTEEPLMCA 157 G L E++ V + + S+G PI+ GN++QK KY+ + + A Sbjct: 61 GADVVSYILAIHEISRISAAVGVILSVHTSVGTNPILYFGNEEQKMKYIPNLASGDHLGA 120 Query: 158 YCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANK 217 + +TEP +GSD ++T A KK +Y++NG K++ITNGG A+ Y A + PD Sbjct: 121 FALTEPHSGSDAGSLRTTAIKKNGKYLLNGSKIFITNGGAADIYITFALTAPD---QGRH 177 Query: 218 AFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAF 277 + FIVE +TPG +G+KE +G S+T ++F++ +VP+ N+L +G GF +AM Sbjct: 178 GISAFIVEKNTPGFTVGKKERKLGLYGSNTTELIFDNAEVPEANLLGKEGDGFHIAMANL 237 Query: 278 DKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSY 337 + R +AA A+G+A+ AL+ A YA +R FG+ + +Q ISF LA+MA + E AR Sbjct: 238 NVGRIGIAAQALGIAEAALEHAVDYAKQRVQFGRPIAANQGISFKLADMATRAEAARHLV 297 Query: 338 QRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIY 397 AA + G AS+AK FA D A + A DAVQI GG G+ +YPVE+L+RDAK+ Sbjct: 298 YHAADLHNRGLNCGKEASMAKQFASDAAVKAALDAVQIYGGYGYMKDYPVERLLRDAKVT 357 Query: 398 QIYEGTSQIQRLIVAREHI 416 QIYEGT++IQRLI+++ + Sbjct: 358 QIYEGTNEIQRLIISKYLL 376 >4U83-A nrPDB Length = 382 Score = 451 bits (1160), Expect = e-127, Method: Composition-based stats. Identities = 146/376 (38%), Positives = 220/376 (58%), Gaps = 4/376 (1%) Query: 39 FEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGL 98 T+ Q++ + AR FA+E + P AA D+ +P + LG + PE GG Sbjct: 8 MLLTDTQEQIREAARDFAQERLAPGAAARDREHAFPRAELTEMGALGFLGMLAPEEWGGS 67 Query: 99 GLGTFDACLISEELAYGCTGVQTAIEGNS-LGQMPIIIAGNDQQKKKYLGRMTEEPLMCA 157 L L EE+A G T + +S +G MPI+ G + QK+++L +M + Sbjct: 68 DLDMVAYALALEEIAAGDGACSTIVSVHSSVGCMPILRFGTEDQKRRFLPKMACGEWIGG 127 Query: 158 YCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANK 217 + +TEP AGSD + +KT+A GD Y+I+G K +IT+G N + A +DP A K Sbjct: 128 FALTEPQAGSDASALKTRARLDGDHYVIDGSKQFITSGKNGNVVIVFAVTDP---AAGKK 184 Query: 218 AFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAF 277 + FIV DTPG ++ E +GQ SDT + F +++VP EN L +G G+K+A+ Sbjct: 185 GISAFIVPTDTPGYEVMSVEHKLGQHSSDTCALGFTNMRVPVENRLGAEGEGYKIALANL 244 Query: 278 DKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSY 337 + R +AA AVG+A+ A + A YA ER TFGK ++EHQA++F LA+MA ++E AR Sbjct: 245 EGGRIGIAAQAVGMARAAFEAARDYARERITFGKPIIEHQAVAFRLADMATRIETARQMV 304 Query: 338 QRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIY 397 AA ++G+ AS+AK A ++A Q+ + A+QI GG G+ +YPVE++ RD ++ Sbjct: 305 LHAAALREAGKPCLTEASMAKLVASEMAEQVCSAAIQIHGGYGYLADYPVERIYRDVRVC 364 Query: 398 QIYEGTSQIQRLIVAR 413 QIYEGTS +QRL++AR Sbjct: 365 QIYEGTSDVQRLVIAR 380 >4M9A-A nrPDB Length = 385 Score = 448 bits (1153), Expect = e-126, Method: Composition-based stats. Identities = 142/380 (37%), Positives = 216/380 (56%), Gaps = 4/380 (1%) Query: 37 FSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCG 96 +TE Q+ AR F E + P AA++D+ P ++ + ELG + +P + G Sbjct: 9 MDDLYTEDQRMILDAARAFCAEVLAPNAAQWDRESHLPDEVVAQMGELGFLGMIVPADWG 68 Query: 97 GLGLGTFDACLISEELAYGCTGVQTAIE-GNSLGQMPIIIAGNDQQKKKYLGRMTEEPLM 155 G L EE+A GC T + NS+G P++ G +QK+++L + + Sbjct: 69 GSYTDYVAYALALEEIAAGCASCATLVSVHNSVGCGPVLNYGTTEQKERWLRDLASGKTV 128 Query: 156 CAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA 215 A+ +TEP AGS+ ++T+AE + ++I+NG K ++TNG +A + A +DPD Sbjct: 129 GAFSLTEPHAGSEAHNLRTRAELRDGKWILNGSKQFVTNGARAGLAIVFAMTDPD---EG 185 Query: 216 NKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMG 275 + + F+V DTPG +G+ E MG R SDT I E+ +P+EN+L G G K+A+ Sbjct: 186 KRGLSAFVVPTDTPGFIVGKPEKKMGIRASDTCPITLENCAIPQENLLGKRGEGLKIALS 245 Query: 276 AFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARM 335 + R +AA A G+A+ A D A +YA ER FGK + EHQAI+ LA MA ++ AR+ Sbjct: 246 NLEGGRIGIAAQATGIARAAFDRARRYARERVQFGKPIAEHQAIAEKLANMATQINAARL 305 Query: 336 SYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAK 395 AA +G AS AK FA ++A + +DA+QI GG GF +Y VE+ RDA+ Sbjct: 306 LTHHAARLRTAGLPCLSEASQAKLFASEMAEAVCSDAIQIHGGYGFLVDYEVERHYRDAR 365 Query: 396 IYQIYEGTSQIQRLIVAREH 415 I QIYEGTS++QR+++AR+ Sbjct: 366 ITQIYEGTSEVQRMVIARQL 385 >6FAH-C nrPDB Length = 379 Score = 444 bits (1141), Expect = e-125, Method: Composition-based stats. Identities = 142/382 (37%), Positives = 220/382 (57%), Gaps = 5/382 (1%) Query: 39 FEFTEQQKEFQATARKFAREEIIP-VAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGG 97 F+EQ K + AR FA +E+ + E +++GE+P ++ + + G IP++ GG Sbjct: 1 MYFSEQNKMIRKLARDFAEKELTTEILDEVEESGEFPQEILDKMAKFGFFGIKIPKSLGG 60 Query: 98 LGLGTFDACLISEELAYGCTGVQTAIEG-NSLGQMPIIIAGNDQQKKKYLGRMTEEPLMC 156 G + EE A + NSL P++++G ++Q +KYL + Sbjct: 61 SGGDHMSYVICMEEFARVSGVASVYLSSPNSLAGGPLLLSGTEEQIEKYLKPIITGKKKL 120 Query: 157 AYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPAN 216 A+ +TEPGAGSD G+ T A GD Y++NG+K +IT + + A++D + Sbjct: 121 AFALTEPGAGSDAGGMSTTAVDMGDYYLLNGRKTFITMAPLCDDAVIYAKTD---MSKGT 177 Query: 217 KAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGA 276 + + FIV+ + G+ +G+ E MG T I+ EDVKVPKEN L GF AM Sbjct: 178 RGISAFIVDLKSEGVSMGKNEHKMGLIGCATSDIIMEDVKVPKENRLGEVNKGFSNAMKT 237 Query: 277 FDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMS 336 D R VA+ ++G+AQ ALDEA KYA ERK FGK + + QAI+FM+A+MA K+E A++ Sbjct: 238 LDVGRLGVASQSIGVAQGALDEAIKYAKERKQFGKRIADFQAIAFMIADMATKLEAAKLL 297 Query: 337 YQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKI 396 AA +D+ + T AS+AK +A +I N++ AVQI GG G+ EY VE++ RD ++ Sbjct: 298 VYNAASLMDNKKNATKEASMAKFYASEICNEICAKAVQIHGGYGYIKEYKVERMYRDCRV 357 Query: 397 YQIYEGTSQIQRLIVAREHIDK 418 + IYEGTSQ+Q+++++ + K Sbjct: 358 FTIYEGTSQVQQMVISGMLLKK 379 >1BUC-A nrPDB Length = 383 Score = 440 bits (1133), Expect = e-124, Method: Composition-based stats. Identities = 157/386 (40%), Positives = 219/386 (56%), Gaps = 8/386 (2%) Query: 37 FSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCG 96 F T+ Q++F A F +++ P E D G Y LI LG+ + E G Sbjct: 1 MDFNLTDIQQDFLKLAHDFGEKKLAPTVTERDHKGIYDKELIDELLSLGITGAYFEEKYG 60 Query: 97 GLGLG---TFDACLISEELAYGCTGVQTAIEGN-SLGQMPIIIAGNDQQKKKYLGRMTEE 152 G G L EELA GV + SL PI G + QK+K+L + E Sbjct: 61 GSGDDGGDVLSYILAVEELAKYDAGVAITLSATVSLCANPIWQFGTEAQKEKFLVPLVEG 120 Query: 153 PLMCAYCVTEPGAGSDVAGIKTKAEKKGDE-YIINGQKMWITNGGKANWYFLLARSDPDP 211 + A+ +TEP AG+D +G +T A K D Y +NG K++ITNGG A+ Y + A +D Sbjct: 121 TKLGAFGLTEPNAGTDASGQQTIATKNDDGTYTLNGSKIFITNGGAADIYIVFAMTD--- 177 Query: 212 KAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFK 271 K+ N T FI+E TPG G+KE MG S T +VF+DVKVP EN+L +G GFK Sbjct: 178 KSKGNHGITAFILEDGTPGFTYGKKEDKMGIHTSQTMELVFQDVKVPAENMLGEEGKGFK 237 Query: 272 VAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVE 331 +AM D R VAA A+G+A+ AL +A +Y+ +R FGK L + Q+ISF LA+M M++E Sbjct: 238 IAMMTLDGGRIGVAAQALGIAEAALADAVEYSKQRVQFGKPLCKFQSISFKLADMKMQIE 297 Query: 332 LARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLM 391 AR +AA + G+ T A+IAK A D+A ++ T+AVQI GG G++ EYPV + M Sbjct: 298 AARNLVYKAACKKQEGKPFTVDAAIAKRVASDVAMRVTTEAVQIFGGYGYSEEYPVARHM 357 Query: 392 RDAKIYQIYEGTSQIQRLIVAREHID 417 RDAKI QIYEGT+++Q ++ + Sbjct: 358 RDAKITQIYEGTNEVQLMVTGGALLR 383 >3PFD-A nrPDB Length = 393 Score = 437 bits (1125), Expect = e-123, Method: Composition-based stats. Identities = 149/380 (39%), Positives = 222/380 (58%), Gaps = 4/380 (1%) Query: 39 FEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGL 98 F+ E+ + R A +EI P AAE D+ +P + G H+PE GG Sbjct: 17 FQLPEEHIALREAIRALAEKEIAPYAAEVDEKARFPEEALAALNSSGFSAIHVPEEYGGQ 76 Query: 99 GLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAY 158 G + C++ EE+A N LG M +I+ G+++ KK+ L + M +Y Sbjct: 77 GADSVATCIVIEEVARVDCSASLIPAVNKLGTMGLILRGSEELKKQVLPAVASGEAMASY 136 Query: 159 CVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKA 218 ++E AGSD A ++T+A GD++I+NG K WITNGGK+ WY ++A +DPD Sbjct: 137 ALSEREAGSDAASMRTRAVADGDDWILNGSKCWITNGGKSTWYTVMAVTDPD---KGANG 193 Query: 219 FTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFD 278 + F+V D G +G KE +G + S T + FE+ ++P + ++ G GFK A+ D Sbjct: 194 ISAFMVHKDDEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRIIGEPGTGFKTALATLD 253 Query: 279 KTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQ 338 TRP + A AVG+AQ ALD A Y ERK FG+ + ++Q + FMLA+MAMK+E AR+ Sbjct: 254 HTRPTIGAQAVGIAQGALDAAIAYTKERKQFGRPVSDNQGVQFMLADMAMKIEAARLMVY 313 Query: 339 RAAWEVDSGRRNTYYASIA-KAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIY 397 AA + G + + S A K FA D+A ++ TDAVQ+ GG G+ ++PVE++MRDAKI Sbjct: 314 SAAARAERGEGDLGFISAASKCFASDVAMEVTTDAVQLFGGYGYTQDFPVERMMRDAKIT 373 Query: 398 QIYEGTSQIQRLIVAREHID 417 QIYEGT+QIQR++++R + Sbjct: 374 QIYEGTNQIQRVVMSRALLR 393 >4O5M-A nrPDB Length = 390 Score = 437 bits (1125), Expect = e-123, Method: Composition-based stats. Identities = 134/385 (34%), Positives = 209/385 (54%), Gaps = 4/385 (1%) Query: 37 FSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCG 96 +F E+ + + T R+FA I P+AAE D+ ++P+ L R ELG++ PE+ G Sbjct: 9 MNFGLGEEIEALRDTVRRFAESRIAPLAAETDRNNQFPMHLWREFGELGVLGITAPEDYG 68 Query: 97 GLGLGTFDACLISEELAYGCTGVQTAIEGNS-LGQMPIIIAGNDQQKKKYLGRMTEEPLM 155 G G+G C+ EE++ + + +S L I G+ +Q+ KYL ++ + Sbjct: 69 GAGMGYLAHCIAMEEISRASASIGLSYGAHSNLCVNQITRNGSPEQRAKYLPKLISGEHV 128 Query: 156 CAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA 215 A ++EPGAGSDV +K AEK+GD Y++NG KMWITNG A+ + A++D + Sbjct: 129 GALAMSEPGAGSDVVSMKLAAEKRGDRYVLNGNKMWITNGPDADVLVVYAKTD---LSAG 185 Query: 216 NKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMG 275 + + FI+E G +K +G R S+T +VFED +VP EN+L +G G V M Sbjct: 186 PRGISAFIIEKGFKGFSTAQKLDKLGMRGSNTCELVFEDCEVPAENLLGTEGKGVNVLMS 245 Query: 276 AFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARM 335 D R V+A G +G+ LD Y ERK F + + E Q + LA+M + +R Sbjct: 246 GLDYERVVLAGGPLGIMAACLDVVVPYVHERKQFDQPIGEFQLMQCKLADMYVTFNASRA 305 Query: 336 SYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAK 395 A D G A+ ++ + A Q+A A+Q LGGNG+ +YP +L+RDAK Sbjct: 306 YVYAVAAACDRGETTRKDAAGCILYSAENATQMALQAIQSLGGNGYINDYPTGRLLRDAK 365 Query: 396 IYQIYEGTSQIQRLIVAREHIDKYK 420 +Y+I GTS+I+R+++ RE + + Sbjct: 366 LYEIGAGTSEIRRMLIGRELFQETR 390 >1IVH-A nrPDB Length = 394 Score = 433 bits (1114), Expect = e-122, Method: Composition-based stats. Identities = 127/376 (33%), Positives = 202/376 (53%), Gaps = 4/376 (1%) Query: 41 FTEQQKEFQATARKFAREEIIPVAAEYDKTGEYP--VPLIRRAWELGLMNTHIPENCGGL 98 +E+Q++ + T KF +E + P A E D++ E+ ++ LG++ P GG Sbjct: 13 LSEEQRQLRQTMAKFLQEHLAPKAQEIDRSNEFKNLREFWKQLGNLGVLGITAPVQYGGS 72 Query: 99 GLGTFDACLISEELAYGCTGVQTAIEGNS-LGQMPIIIAGNDQQKKKYLGRMTEEPLMCA 157 GLG + L+ EE++ V + +S L ++ GN+ QK+KYL ++ + A Sbjct: 73 GLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGA 132 Query: 158 YCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANK 217 ++EP AGSDV +K KAEKKG+ YI+NG K WITNG A+ + A++D PA++ Sbjct: 133 LAMSEPNAGSDVVSMKLKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDL-AAVPASR 191 Query: 218 AFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAF 277 T FIVE PG +K +G R S+T ++FED K+P N+L + G V M Sbjct: 192 GITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGL 251 Query: 278 DKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSY 337 D R V+A G +GL Q LD Y R+ FG+ + Q + +A+M ++ R Sbjct: 252 DLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYV 311 Query: 338 QRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIY 397 A D G + ++ + A Q+A D +Q GGNG+ ++P+ + +RDAK+Y Sbjct: 312 YNVAKACDEGHCTAKDCAGVILYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDAKLY 371 Query: 398 QIYEGTSQIQRLIVAR 413 +I GTS+++RL++ R Sbjct: 372 EIGAGTSEVRRLVIGR 387 >4KTO-A nrPDB Length = 410 Score = 429 bits (1104), Expect = e-121, Method: Composition-based stats. Identities = 145/386 (37%), Positives = 214/386 (55%), Gaps = 4/386 (1%) Query: 36 GFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENC 95 G +F E+ +A+ R+FA E I P+A + D++ +P+ L R ELGL+ E Sbjct: 28 GLNFALGEEIDALRASVRRFASERIAPLADDADRSNAFPMSLWREMGELGLLGITADEAH 87 Query: 96 GGLGLGTFDACLISEELAYGCTGVQTAIEGNS-LGQMPIIIAGNDQQKKKYLGRMTEEPL 154 GG GLG C+ EE++ V + +S L I G QK +YL ++ Sbjct: 88 GGAGLGYLAHCVAMEEISRASASVGLSYGAHSNLCVNQINRNGKPAQKSRYLPKLISGEH 147 Query: 155 MCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAP 214 + A ++EPGAGSDV +K KA+K+GD Y++NG KMWITNG A+ + A++DP A Sbjct: 148 VGALAMSEPGAGSDVVSMKLKADKRGDRYVLNGSKMWITNGPDADVLVVYAKTDP---AA 204 Query: 215 ANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAM 274 + T F+VE PG G+K +G R S+T ++F D +VP+ENVL G G G KV M Sbjct: 205 GPRGITAFLVEKAFPGFSAGQKLDKLGMRGSNTSELIFTDCEVPEENVLGGVGEGVKVLM 264 Query: 275 GAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELAR 334 D R V++AG +G+ LD Y ERK FG+ + E Q + LA+M + + AR Sbjct: 265 SGLDYERVVLSAGPLGIMAACLDVVVPYLHERKQFGQPIGEFQLMQGKLADMYVTMNAAR 324 Query: 335 MSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDA 394 A D G A+ +A + A +A +A+Q LGGNG+ +YP +L+RDA Sbjct: 325 AYVYAVAAACDRGETARKDAAGCILYAAEKATAMALEAIQALGGNGYTNDYPAGRLLRDA 384 Query: 395 KIYQIYEGTSQIQRLIVAREHIDKYK 420 K+Y+I GTS+I+R+++ RE + K Sbjct: 385 KLYEIGAGTSEIRRMLIGRELFAETK 410 >2JIF-A nrPDB Length = 404 Score = 425 bits (1092), Expect = e-119, Method: Composition-based stats. Identities = 138/380 (36%), Positives = 217/380 (57%), Gaps = 5/380 (1%) Query: 41 FTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGL 100 FT+++ +++ +KFA+E+I P+ + D+ + +I+ ++ GLM + GG G Sbjct: 29 FTDEEMMIKSSVKKFAQEQIAPLVSTMDENSKMEKSVIQGLFQQGLMGIEVDPEYGGTGA 88 Query: 101 GTFDACLISEELAYGCTGVQTAIE-GNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYC 159 L+ EELA V E N+L I G ++QK YL ++T + ++C Sbjct: 89 SFLSTVLVIEELAKVDASVAVFCEIQNTLINTLIRKHGTEEQKATYLPQLTT-EKVGSFC 147 Query: 160 VTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAF 219 ++E GAGSD +KT+A+K+GD Y++NG KMWI++ A + ++A DP K Sbjct: 148 LSEAGAGSDSFALKTRADKEGDYYVLNGSKMWISSAEHAGLFLVMANVDP---TIGYKGI 204 Query: 220 TGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDK 279 T F+V+ DTPG+ IG+ E +G R S T + FE+VKVP+ N+L G G+K A+G+ ++ Sbjct: 205 TSFLVDRDTPGLHIGKPENKLGLRASSTCPLTFENVKVPEANILGQIGHGYKYAIGSLNE 264 Query: 280 TRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQR 339 R +AA +GLAQ D Y ER FGK L + Q + +A +A ++E AR+ Sbjct: 265 GRIGIAAQMLGLAQGCFDYTIPYIKERIQFGKRLFDFQGLQHQVAHVATQLEAARLLTYN 324 Query: 340 AAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQI 399 AA +++G+ AS+AK +A +IA Q + ++ +GG G+ +YPVEK RDAKI I Sbjct: 325 AARLLEAGKPFIKEASMAKYYASEIAGQTTSKCIEWMGGVGYTKDYPVEKYFRDAKIGTI 384 Query: 400 YEGTSQIQRLIVAREHIDKY 419 YEG S IQ +A+ +Y Sbjct: 385 YEGASNIQLNTIAKHIDAEY 404 >1RX0-A nrPDB Length = 393 Score = 424 bits (1091), Expect = e-119, Method: Composition-based stats. Identities = 129/399 (32%), Positives = 222/399 (55%), Gaps = 9/399 (2%) Query: 21 RSQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRR 80 ++ H +P +G + E+QKEFQ A FA E+ P AE+D+ +PV ++R+ Sbjct: 3 QTGHRSLTSCIDPSMGLN----EEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRK 58 Query: 81 AWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQ 140 A +LG +I + GG GL D +I E LA GCT I +++ I GN++ Sbjct: 59 AAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEE 118 Query: 141 QKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANW 200 Q+ K+ + +YC+TEPG+GSD A + T A+K+GD YI+NG K +I+ G+++ Sbjct: 119 QRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDI 178 Query: 201 YFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKE 260 Y ++ R+ P K + +VE TPG+ G+KE +G TR ++FED VP Sbjct: 179 YVVMCRT----GGPGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVA 234 Query: 261 NVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAIS 320 N + +G GF +A+ + R +A+ ++G A ++ + RK FG+ L +Q + Sbjct: 235 NRIGSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQ 294 Query: 321 FMLAEMAMKVELARMSYQRAAWEV-DSGRRNTYYASIAKAFAGDIANQLATDAVQILGGN 379 F LA+MA ++ AR+ + AA + + + S+AK FA D + A+Q+ GG Sbjct: 295 FTLADMATRLVAARLMVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGY 354 Query: 380 GFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDK 418 G+ +Y V++ +RD++++QI EG++++ R++++R + + Sbjct: 355 GYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSLLQE 393 >4IV6-A nrPDB Length = 388 Score = 420 bits (1081), Expect = e-118, Method: Composition-based stats. Identities = 132/383 (34%), Positives = 219/383 (57%), Gaps = 3/383 (0%) Query: 38 SFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGG 97 S T +++ T F +++ PV E + YP LI E+G+ IPE G Sbjct: 4 SMALTAEEETIVKTVHDFVEKQVKPVVRELEHANTYPEELIETMKEIGIFGLAIPEPYGF 63 Query: 98 LGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCA 157 + ++EELA G + A+ G+++ +++ G ++QK+KYL RM L Sbjct: 64 GAVSMPCYVQVAEELARGWMSLAGAMGGHTVVSKLLLLFGTEEQKQKYLPRMATGELRAT 123 Query: 158 YCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANK 217 +TEPG GSD+ ++T A + GD+Y+ING K WI+N +++ L+ ++DPD + PA+K Sbjct: 124 MALTEPGGGSDLQAMRTVARRDGDDYVINGSKTWISNARRSDLVALMCKTDPDAQ-PAHK 182 Query: 218 AFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLI-GDGAGFKVAMGA 276 + +VE PG + R +G + ++ + F D +VP ++L +G GF M Sbjct: 183 GVSILLVEK-VPGFDVSRDLPKLGYKGVESCELNFTDARVPVSSLLGDDEGRGFAQMMKG 241 Query: 277 FDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMS 336 + R VAA A G+A+ A ++A +Y+ ER++FGK + +HQ++ MLA+M K+ AR Sbjct: 242 LEVGRLQVAARATGVARAAFEDALRYSQERESFGKPIWQHQSVGNMLADMGTKLYAARSL 301 Query: 337 YQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKI 396 AA + D+G+R A +AK FA + A Q+A DAV++ GG G++TEY VE+ RDA + Sbjct: 302 LLSAAEKFDAGQRCDMEAGMAKLFASETAMQIALDAVRVHGGYGYSTEYDVERYFRDAPL 361 Query: 397 YQIYEGTSQIQRLIVAREHIDKY 419 + EGT++IQR ++A++ + + Sbjct: 362 MIVGEGTNEIQRNVIAKQLVARG 384 >2PG0-A nrPDB Length = 385 Score = 413 bits (1063), Expect = e-116, Method: Composition-based stats. Identities = 128/375 (34%), Positives = 196/375 (52%), Gaps = 1/375 (0%) Query: 41 FTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGL 100 E+ F+A RKF +E P +++K G P + E G + + E GGL Sbjct: 10 LREEHHMFRAAFRKFLEKEAYPHYNDWEKRGIIPRSFWAKMGENGFLCPWVDEKYGGLNA 69 Query: 101 GTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCV 160 + +I+EEL + + N + I G ++QK+K+L + L+ A + Sbjct: 70 DFAYSVVINEELEKVGSSLVGIGLHNDIVTPYIASYGTEEQKQKWLPKCVTGELITAIAM 129 Query: 161 TEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFT 220 TEPGAGSD+A I T A K GD YI+NGQK +ITNG A+ + ++DP K P ++ + Sbjct: 130 TEPGAGSDLANISTTAVKDGDYYIVNGQKTFITNGIHADLIVVACKTDPQAKPP-HRGIS 188 Query: 221 GFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKT 280 +VE DTPG GRK +G DT + F+D KVP N+L +G GF M + Sbjct: 189 LLVVERDTPGFTRGRKLEKVGLHAQDTAELFFQDAKVPAYNLLGEEGKGFYYLMEKLQQE 248 Query: 281 RPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRA 340 R VVA A A+ +Y +R FGK + E Q + F LAEMA ++ L R R Sbjct: 249 RLVVAIAAQTAAEVMFSLTKQYVKQRTAFGKRVSEFQTVQFRLAEMATEIALGRTFVDRV 308 Query: 341 AWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIY 400 E +G++ S+AK + ++A ++A +A+Q+ GG G+ EY + + RD + IY Sbjct: 309 IEEHMAGKQIVTEVSMAKWWITEMAKRVAAEAMQLHGGYGYMEEYEIARRYRDIPVSAIY 368 Query: 401 EGTSQIQRLIVAREH 415 GT+++ + I+AR+ Sbjct: 369 AGTNEMMKTIIARQL 383 >2DVL-A nrPDB Length = 372 Score = 410 bits (1055), Expect = e-115, Method: Composition-based stats. Identities = 153/378 (40%), Positives = 222/378 (58%), Gaps = 9/378 (2%) Query: 39 FEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGL 98 T++Q+ R+ ARE + P+A EYD+ EYP P ++ ELGL+ PE GG+ Sbjct: 1 MTLTQEQRLVLDAVRRVAREVLYPLAPEYDRKAEYPWPQLKALAELGLLGMTTPEEWGGV 60 Query: 99 GLGTFDACLISEELAYGCTGVQTAIEGNS-LGQMPIIIAGNDQQKKKYLGRMTEEPLMCA 157 GL + L EELA V + S L Q ++ G++ QK++YL + + A Sbjct: 61 GLDSVTWALALEELAAADPSVAVIVSVTSGLPQYMLLRFGSEAQKRRYLVPLARGEWIGA 120 Query: 158 YCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANK 217 +C+TEP AGSD ++ +A + +++NG K WIT+ G A+ Y ++AR++ K Sbjct: 121 FCLTEPQAGSDAKSLRAEARRVKGGFVLNGVKSWITSAGHAHLYVVMARTE--------K 172 Query: 218 AFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAF 277 + F+VE TPG+ GR E MG + T + E+V VP+EN+L +G G A+ Sbjct: 173 GISAFLVEKGTPGLSFGRPEEKMGLHAAHTAEVRLEEVFVPEENLLGEEGRGLAYALAGL 232 Query: 278 DKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSY 337 D R VAA AVG+A+ A + A YA ER+ FGK L EHQAI+F +A+M +K+ AR Sbjct: 233 DSGRVGVAAQAVGIARGAFEIAKAYAEEREQFGKKLKEHQAIAFKIADMHVKIAAARALV 292 Query: 338 QRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIY 397 AA + D G R T AS AK FA A ++ +AVQ+LGG G++ +Y VE+ RDAK+ Sbjct: 293 LEAARKKDRGERFTLEASAAKLFASAAAVEVTREAVQVLGGYGYHRDYRVERYYRDAKVT 352 Query: 398 QIYEGTSQIQRLIVAREH 415 +IYEGTS+IQRL++ARE Sbjct: 353 EIYEGTSEIQRLVIAREL 370 >4IRN-A nrPDB Length = 416 Score = 407 bits (1045), Expect = e-114, Method: Composition-based stats. Identities = 115/388 (29%), Positives = 202/388 (52%), Gaps = 6/388 (1%) Query: 29 RQREPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMN 88 +Q G F F + QQ +F+ +FA++ +I + DK + ++ E G+ Sbjct: 28 QQMGRGSEFDFAWNSQQIQFRKKVIQFAQQSLISDLIKNDKEEIFNRDAWQKCSEFGVHG 87 Query: 89 THIPENCGGLGLGTFDACLISEELAYGC--TGVQTAIEGNSLGQ-MPIIIAGNDQQKKKY 145 IP GG L + L YGC G+ A+ + MP++ G ++QK+KY Sbjct: 88 WPIPARYGGQELDILTTAYALQGLGYGCKDNGLIFAMNAHIWACEMPLLTFGTEEQKEKY 147 Query: 146 LGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLA 205 L + + ++ TEP AGSD+ +KT A+K GD+YI+NG K ++TNG A+ + + A Sbjct: 148 LPLLCRGGWIASHAATEPQAGSDIYSLKTTAQKDGDKYILNGYKHYVTNGTIADLFIIFA 207 Query: 206 RSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIG 265 DP + + T F++E DTPG+ + + MG R ++ + E+ +V N L Sbjct: 208 TIDP---SLGKEGLTTFMIEKDTPGLILSKPISKMGMRTAEVPELRLENCEVSAANRLGE 264 Query: 266 DGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAE 325 +G G + + + R + A AVG +R L+++ +YA K FG+ + + Q ++ L E Sbjct: 265 EGTGLAIFNHSMEWERGFILAAAVGTMERLLEQSIRYARSHKQFGQAIGKFQLVANKLVE 324 Query: 326 MAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEY 385 M +++E A+ + AW ++ + AS+A + + Q +A++I G G+ T Sbjct: 325 MKLRLENAKAYLYKVAWMKENKQMALLEASMANLYISEAWVQSCLEAIEIHGAYGYLTNT 384 Query: 386 PVEKLMRDAKIYQIYEGTSQIQRLIVAR 413 +E+ +RDA + Y GTS+IQR+++A+ Sbjct: 385 ELERELRDAIASKFYSGTSEIQRVVIAK 412 >3MPI-A nrPDB Length = 397 Score = 399 bits (1026), Expect = e-112, Method: Composition-based stats. Identities = 136/390 (34%), Positives = 218/390 (55%), Gaps = 10/390 (2%) Query: 37 FSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYP-VPLIRRAWELGLMNTHIPENC 95 F +++ + Q R F ++I+P A ++D +P +R ELG T IPE Sbjct: 1 MDFNLSKELQMLQKEVRNFVNKKIVPFADQWDNENHFPYEEAVRPMGELGFFGTVIPEEY 60 Query: 96 GGLGLG--TFDACLISEELAYGCTGVQTAIEGNSLG-QMPIIIAGNDQQKKKYLGRMTEE 152 GG G+ A +++EE+A G + ++ + LG I+ G++ KKKY+ +++ Sbjct: 61 GGEGMDQGWLAAMIVTEEIARGSSALRVQLNMEVLGCAYTILTYGSEALKKKYVPKLSSA 120 Query: 153 PLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPK 212 + + +TEP AGSDV + + AE KGD +++NG K WI+N +A+ A +D K Sbjct: 121 EFLGGFGITEPDAGSDVMAMSSTAEDKGDHWLLNGSKTWISNAAQADVLIYYAYTD---K 177 Query: 213 APANKAFTGFIV-EADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFK 271 A ++ + F++ + PGI+ E +G S T + ++VKVPKEN+L G G + Sbjct: 178 AAGSRGLSAFVIEPRNFPGIKTSNLE-KLGSHASPTGELFLDNVKVPKENILGKPGDGAR 236 Query: 272 VAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVE 331 + G+ + TR AAG VGLAQ LD A KY ER+ FGK + + Q M+A+MA++VE Sbjct: 237 IVFGSLNHTRLSAAAGGVGLAQACLDAAIKYCNERRQFGKPIGDFQMNQDMIAQMAVEVE 296 Query: 332 LARMSYQRAAWEVDSGRRNT-YYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKL 390 AR+ +AA D GR N ++AK AG+ ++ A A++ILG G++TEYPV + Sbjct: 297 AARLLAYKAAAAKDEGRLNNGLDVAMAKYAAGEAVSKCANYAMRILGAYGYSTEYPVARF 356 Query: 391 MRDAKIYQIYEGTSQIQRLIVAREHIDKYK 420 RDA Y + EG++ I ++I+A + + K Sbjct: 357 YRDAPTYYMVEGSANICKMIIALDQLGVRK 386 >3GNC-A nrPDB Length = 399 Score = 398 bits (1024), Expect = e-111, Method: Composition-based stats. Identities = 116/397 (29%), Positives = 184/397 (46%), Gaps = 17/397 (4%) Query: 18 FHWRSQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPL 77 FHW + L + + ++ + A +A+ ++ P E + + Sbjct: 10 FHW-----------DDPLLLDQQLADDERMVRDAAHAYAQGKLAPRVTEAFRHETTDAAI 58 Query: 78 IRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIE-GNSLGQMPIIIA 136 R E+GL+ IPE GG GL LI+ E+ +G ++ + +SL +PI Sbjct: 59 FREMGEIGLLGPTIPEQYGGPGLDYVSYGLIAREVERVDSGYRSMMSVQSSLVMVPIFEF 118 Query: 137 GNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGG 196 G+D QK+KYL ++ + + +TEP GSD + T+A K Y ++G KMWITN Sbjct: 119 GSDAQKEKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRARKVPGGYSLSGSKMWITNSP 178 Query: 197 KANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVK 256 A+ + + A+ D D + GFI+E G+ +G R S T IV ++ Sbjct: 179 IADVFVVWAKLDEDGRDE----IRGFILEKGCKGLSAPAIHGKVGLRASITGEIVLDEAF 234 Query: 257 VPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEH 316 VP+EN+L G + + R +A GA+G A+ A +Y L+RK FG+ L + Sbjct: 235 VPEENIL-PHVKGLRGPFTCLNSARYGIAWGALGAAESCWHIARQYVLDRKQFGRPLAAN 293 Query: 317 QAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQIL 376 Q I LA+M ++ L R D G SI K + A +A A +L Sbjct: 294 QLIQKKLADMQTEITLGLQGVLRLGRMKDEGTAAVEITSIMKRNSCGKALDIARLARDML 353 Query: 377 GGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAR 413 GGNG + E+ V + + + ++ YEGT I LI+ R Sbjct: 354 GGNGISDEFGVARHLVNLEVVNTYEGTHDIHALILGR 390 >3NF4-A nrPDB Length = 387 Score = 398 bits (1022), Expect = e-111, Method: Composition-based stats. Identities = 141/372 (37%), Positives = 212/372 (56%), Gaps = 5/372 (1%) Query: 42 TEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLG 101 +++ E R+ A + + P+ ++K YP + + GL++ PE GG G Sbjct: 17 SQEAAELIELTREIADKVLDPIVDRHEKDETYPEGVFEQLGAAGLLSLPQPEEWGGGGQP 76 Query: 102 TFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVT 161 + EE+A V A+ +SL P+++ G ++QKK++L M + AY ++ Sbjct: 77 YEVYLQVLEEIAARWASVAVAVSVHSLSSHPLLVFGTEEQKKRWLPGMLSGEQIGAYSLS 136 Query: 162 EPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTG 221 EP AGSD A ++ A Y+ING K WIT+GGKA++Y L AR+ ++ + Sbjct: 137 EPQAGSDAAALRCAATPTDGGYVINGSKSWITHGGKADFYTLFART-----GEGSRGVSC 191 Query: 222 FIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTR 281 F+V AD PG+ G+ E MG T +++ ++ + + +G G ++A A D R Sbjct: 192 FLVPADQPGLSFGKPEEKMGLHAVPTTSAFYDNARIDADRRIGEEGQGLQIAFSALDSGR 251 Query: 282 PVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAA 341 +AA A GLAQ ALDEA YA ER FG+ +++HQ + F+LA+MA V AR +Y AA Sbjct: 252 LGIAAVATGLAQAALDEAVAYANERTAFGRKIIDHQGLGFLLADMAAAVATARATYLDAA 311 Query: 342 WEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYE 401 D GR + ASIAK A D A ++ TDAVQ+ GG G+ +Y VE+ MR+AKI QI+E Sbjct: 312 RRRDQGRPYSQQASIAKLTATDAAMKVTTDAVQVFGGVGYTRDYRVERYMREAKIMQIFE 371 Query: 402 GTSQIQRLIVAR 413 GT+QIQRL++AR Sbjct: 372 GTNQIQRLVIAR 383 >2CX9-A nrPDB Length = 387 Score = 393 bits (1009), Expect = e-109, Method: Composition-based stats. Identities = 148/386 (38%), Positives = 224/386 (58%), Gaps = 2/386 (0%) Query: 35 LGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPEN 94 +G FE ++++ R+F + E+ P AAE D+TG +P L+R+ E G+ +PE Sbjct: 1 MGLWFEEGAEERQVLGPFREFLKAEVAPGAAERDRTGAFPWDLVRKLAEFGVFGALVPEA 60 Query: 95 CGGLGLGTFDACLISEELAYGCTGVQTAI-EGNSLGQMPIIIAGNDQQKKKYLGRMTEEP 153 GG GL T + E +AY + + NSL I++AG++ QK+ +L ++ Sbjct: 61 YGGAGLSTRLFARMVEAIAYYDGALALTVASHNSLATGHILLAGSEAQKEAFLPKLASGE 120 Query: 154 LMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKA 213 + A+ +TEPG+GSD A +KTKAEK + +NG K +IT G A Y ++AR+DP P Sbjct: 121 ALGAWGLTEPGSGSDAAALKTKAEKVEGGWRLNGTKQFITQGSVAGVYVVMARTDPPPSP 180 Query: 214 PANK-AFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKV 272 + F G+++GRKE +G SDT ++ ED+ VP+E +L G GF Sbjct: 181 ERKHQGISAFAFFRPERGLKVGRKEEKLGLTASDTAQLILEDLFVPEEALLGERGKGFYD 240 Query: 273 AMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVEL 332 + D R +AA AVGL Q ALD A YA R+ FG+ + E + +SF LAE A ++E Sbjct: 241 VLRVLDGGRIGIAAMAVGLGQAALDYALAYAKGREAFGRPIAEFEGVSFKLAEAATELEA 300 Query: 333 ARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMR 392 AR+ Y +AA D+GR T A+ AK FA + A + +A+QILGG G+ +YPVE+ R Sbjct: 301 ARLLYLKAAELKDAGRPFTLEAAQAKLFASEAAVKACDEAIQILGGYGYVKDYPVERYWR 360 Query: 393 DAKIYQIYEGTSQIQRLIVAREHIDK 418 DA++ +I EGTS+I +L++AR ++ Sbjct: 361 DARLTRIGEGTSEILKLVIARRLLEA 386 >2Z1Q-A nrPDB Length = 577 Score = 385 bits (990), Expect = e-107, Method: Composition-based stats. Identities = 142/396 (35%), Positives = 215/396 (54%), Gaps = 24/396 (6%) Query: 40 EFTEQQKEFQATARKFAREEIIPVAAEYDKTG-EYPVPLIRRAWELGLMNTHIPENCGGL 98 +F E KE T R F E++P+ + E VPL+R+A ELGL+ +PE GGL Sbjct: 27 DFDESVKEIARTTRTFVEREVLPLLERMEHGELELNVPLMRKAGELGLLAIDVPEEYGGL 86 Query: 99 GLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAY 158 L + +++EEL+ T S+G +P++ G ++QK+KYL ++ + AY Sbjct: 87 DLPKVISTVVAEELSGSGGFSVTYGAHTSIGTLPLVYFGTEEQKRKYLPKLASGEWIAAY 146 Query: 159 CVTEPGAGSDVAGIKTKAE--KKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPAN 216 C+TEPG+GSD KT+A + G YI+NG K WI+N G A+ + + A+ D Sbjct: 147 CLTEPGSGSDALAAKTRATLSEDGKHYILNGVKQWISNAGFAHLFTVFAKVD-------G 199 Query: 217 KAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGA 276 + FT F+VE DTPG+ G +E MG + S TR ++ EDVKVP ENVL G G K+A Sbjct: 200 EHFTAFLVERDTPGLSFGPEEKKMGIKASSTRQVILEDVKVPVENVLGEIGKGHKIAFNV 259 Query: 277 FDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMS 336 + R + AGAVG A+RAL+ + +YA +R FG+ + I L EMA ++ A + Sbjct: 260 LNVGRYKLGAGAVGGAKRALELSAQYATQRVQFGRPIGRFGLIQQKLGEMASRIYAAESA 319 Query: 337 YQRAAWEVDSG--------------RRNTYYASIAKAFAGDIANQLATDAVQILGGNGFN 382 R +D ASI K ++ + + + VQI GG G++ Sbjct: 320 VYRTVGLIDEALLGKKGPEAVMAGIEEYAVEASIIKVLGSEVLDYVVDEGVQIHGGYGYS 379 Query: 383 TEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDK 418 EYP+E+ RDA+I +I+EGT++I RL++ + + Sbjct: 380 QEYPIERAYRDARINRIFEGTNEINRLLIPGMLLRR 415 >3SF6-A nrPDB Length = 403 Score = 382 bits (982), Expect = e-106, Method: Composition-based stats. Identities = 111/396 (28%), Positives = 184/396 (46%), Gaps = 12/396 (3%) Query: 22 SQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYP-VPLIRR 80 +Q R + +G + + +++E + T R + I P A + + GE P L Sbjct: 11 AQPRSQRRGADDLIGINAVLSAEEREIRDTVRSVVQRRIKPHIASWYEDGELPARELAVE 70 Query: 81 AWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEGN-SLGQMPIIIAGND 139 ELGL+ H+ + G G+ L EL G +G+++ + SL I G+D Sbjct: 71 LGELGLLGMHL-KGYGCAGMSAVAYGLACLELEAGDSGIRSLVSVQGSLAMYAIHAFGSD 129 Query: 140 QQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKAN 199 +QK ++L M + + +TEP GSD AG++T+A + GD++I+ G KMWITNG A+ Sbjct: 130 EQKDQWLPDMASGHRIGCFGLTEPDHGSDPAGMRTRATRSGDDWILTGTKMWITNGSVAD 189 Query: 200 WYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPK 259 + AR+D + GF+V DTPG + M R S T +V + V++P Sbjct: 190 VAVVWARTD--------EGIRGFVVPTDTPGFTANTIKSKMSLRASVTSELVLDGVRLPD 241 Query: 260 ENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAI 319 L G + ++ R + GA+G A+ L+ A YA R+ F + + Q Sbjct: 242 SARLPGA-TSLGAPLRCLNEARFGIVFGALGAARDCLETALAYACSREQFDRPIGGFQLT 300 Query: 320 SFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGN 379 LA+M ++ + + D+G S+ K A ++A A +LG + Sbjct: 301 QQKLADMTLEYGKGFLLALHLGRQKDAGELAPEQVSLGKLNNVREAIEIARTARTVLGAS 360 Query: 380 GFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREH 415 G EYPV + + + YEGTS++ LI+ + Sbjct: 361 GITGEYPVMRHANNLESVLTYEGTSEMHTLIIGQAL 396 >2EBA-A nrPDB Length = 385 Score = 380 bits (977), Expect = e-106, Method: Composition-based stats. Identities = 121/382 (31%), Positives = 189/382 (49%), Gaps = 10/382 (2%) Query: 36 GFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENC 95 T ++KE Q AR+F +E +P ++ + G +P LI R ELG + +P Sbjct: 6 ALEDLLTPEEKEVQKAARRFLEKEALPHIRDWWEEGVFPTHLIPRFAELGFLGPTLPPEY 65 Query: 96 GGLGLGTFDACLISEELAYGCTGVQTAIE-GNSLGQMPIIIAGNDQQKKKYLGRMTEEPL 154 GG G+ + LI EL +G+++ + +SL PI G+++QK+++L ++ + Sbjct: 66 GGAGVSSAAYGLICYELERVDSGLRSFVSVQSSLVMYPIYAYGSEEQKREFLPKLARGEM 125 Query: 155 MCAYCVTEPGAGSDVAG-IKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKA 213 + + +TEP GSD G +KT+A ++GD +++NG KMWITNG A+ + A+ + Sbjct: 126 VGCFGLTEPDGGSDPYGNMKTRARREGDTWVLNGTKMWITNGNLAHLAVIWAKDE----- 180 Query: 214 PANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVA 273 GF+V DTPG Q + M R S T +V E+V+VP+ L G K Sbjct: 181 --GGEVLGFLVPTDTPGFQAREVKRKMSLRASVTSELVLEEVRVPESLRL-PKALGLKAP 237 Query: 274 MGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELA 333 + + R +A GA+G + +EA +A R TFG+ L + Q + LAEM Sbjct: 238 LSCLTQARFGIAWGAMGALEAVYEEAVAFAKSRSTFGEPLAKKQLVQAKLAEMLAWHTEG 297 Query: 334 RMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRD 393 + R A D G+ S+AK A Q A A ILGG+G EY + M + Sbjct: 298 LLLAWRLARLKDEGKLTPAQVSLAKRQNVWKALQAARMARDILGGSGITLEYHAIRHMLN 357 Query: 394 AKIYQIYEGTSQIQRLIVAREH 415 + YEGT + L++ RE Sbjct: 358 LETVYTYEGTHDVHTLVLGREI 379 >3OWA-A nrPDB Length = 597 Score = 380 bits (975), Expect = e-106, Method: Composition-based stats. Identities = 134/402 (33%), Positives = 205/402 (50%), Gaps = 31/402 (7%) Query: 40 EFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVP--LIRRAWELGLMNTHIPENCGG 97 +F+ + K T F E++P EY + E+ L++ A ELGL+ +PE GG Sbjct: 32 DFSSEHKMIAKTTEDFIVNEVLPEL-EYLEQHEFDRSVRLLKEAGELGLLGADVPEEYGG 90 Query: 98 LGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCA 157 +GL + LI+E+ + T +G +PI++ GN++QKKKYL + + A Sbjct: 91 IGLDKVSSALIAEKFSRAGGFAITHGAHVGIGSLPIVLFGNEEQKKKYLPLLATGEKLAA 150 Query: 158 YCVTEPGAGSDVAGIKTKAE--KKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA 215 Y +TEPG+GSD G KT A +G Y++NG+K WITN A+ + + A+ D Sbjct: 151 YALTEPGSGSDALGAKTTARLNAEGTHYVLNGEKQWITNSAFADVFIVYAKID------- 203 Query: 216 NKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMG 275 + F+ FIVE D G+ +E MG +CS TR ++ ED VPKEN+L G G +A Sbjct: 204 GEHFSAFIVEKDYAGVSTSPEEKKMGIKCSSTRTLILEDALVPKENLLGEIGKGHIIAFN 263 Query: 276 AFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARM 335 + R + G VG A+RA++ + +YA +R+ F + + I LA MA K A Sbjct: 264 ILNIGRYKLGVGTVGSAKRAVEISAQYANQRQQFKQPIARFPLIQEKLANMAAKTYAAES 323 Query: 336 SYQRAAWEVDS------------GRRNTY-------YASIAKAFAGDIANQLATDAVQIL 376 S R +S G+ S+ K F ++ + + VQI Sbjct: 324 SVYRTVGLFESRMSTLSEEEVKDGKAVAASIAEYAIECSLNKVFGSEVLDYTVDEGVQIH 383 Query: 377 GGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDK 418 GG GF EY +E++ RD++I +I+EGT++I RLIV + K Sbjct: 384 GGYGFMAEYEIERMYRDSRINRIFEGTNEINRLIVPGTFLRK 425 >6ES9-A nrPDB Length = 551 Score = 373 bits (957), Expect = e-104, Method: Composition-based stats. Identities = 131/388 (33%), Positives = 210/388 (54%), Gaps = 14/388 (3%) Query: 41 FTEQQKEFQATARKFAREEIIPVAAEYD-KTGEYPVPLIRRAWELGLMNTHIPENCGGLG 99 E + + R++A E +IP A E+ K P+ +I ELG+ IPE GGLG Sbjct: 167 LDEDLEMIRDQFRRYAEERVIPNAHEWHLKDQLIPMEIIEELAELGVFGLTIPEEFGGLG 226 Query: 100 LGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYC 159 L +++EEL+ G GV + + + I+ G + QK K+L + ++ Sbjct: 227 LSKASMVVVTEELSRGYIGVGSLGTRSEIAAELILCGGTEAQKAKWLPGLASGEILSTAV 286 Query: 160 VTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAF 219 TEP GSD+ ++T+A + G+++++ G K WIT+ + + LLAR+DP+ + Sbjct: 287 FTEPNTGSDLGSLRTRAVRDGEDWVVTGNKTWITHAQRTHVMTLLARTDPETTD--WRGL 344 Query: 220 TGFIVEAD---------TPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGD-GAG 269 + F+ E + TPG+ G E+ +G R + F+ ++ EN+L G+ G G Sbjct: 345 SMFLAEKEPGTDDDPFPTPGMTGGEIEV-LGYRGMKEYELGFDGFRIKGENLLGGEPGRG 403 Query: 270 FKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMK 329 FK M F+ R AA AVG+AQ A + +YA++RK FGK L+E ++ LA MA++ Sbjct: 404 FKQLMETFESARIQTAARAVGVAQSAAEIGMRYAVDRKQFGKSLIEFPRVADKLAMMAVE 463 Query: 330 VELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEK 389 + +AR +AWE D GRR A +AK +A A +A+QI GGNGF EY + + Sbjct: 464 IMIARQLTYFSAWEKDHGRRCDLEAGMAKLLGARVAWAAADNALQIHGGNGFALEYAISR 523 Query: 390 LMRDAKIYQIYEGTSQIQRLIVAREHID 417 ++ DA+I I+EG ++IQ ++AR +D Sbjct: 524 VLCDARILNIFEGAAEIQAQVIARRLLD 551 >4W9U-A nrPDB Length = 395 Score = 373 bits (957), Expect = e-103, Method: Composition-based stats. Identities = 110/383 (28%), Positives = 181/383 (47%), Gaps = 7/383 (1%) Query: 32 EPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHI 91 E + TE ++ + +A+ FA + ++P + L + GL+ + Sbjct: 10 EDPFLLEEQLTEDERMIRDSAKAFASDVLLPRVEKAYLEETTDPELFHLMGQAGLLGVTL 69 Query: 92 PENCGGLGLGTFDACLISEELAYGCTGVQTAIE-GNSLGQMPIIIAGNDQQKKKYLGRMT 150 PE+ G L++ E+ +G ++ + +SL PI G+D+Q+KKYL + Sbjct: 70 PEDYGAANASYVAYGLVAREVERIDSGYRSMMSVQSSLVMYPIYAYGSDEQRKKYLPGLV 129 Query: 151 EEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPD 210 L+ + +TEP AGSD AG+KT+AEK Y ++G KMWI+N A+ + + A+S Sbjct: 130 SGELIGCFGLTEPDAGSDPAGMKTRAEKIDGGYRLSGSKMWISNSPIADVFVVWAKS--- 186 Query: 211 PKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGF 270 A + A GFI+E G+ + + R S T IV + V+V ++ +L + +G Sbjct: 187 --AAHDNAIRGFILEKGMKGLSAPKIGGKLSLRASITGEIVMDGVEVSEDAIL-PNVSGL 243 Query: 271 KVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKV 330 K G ++ R ++ G +G A+ A +Y L+RK F K L Q LA+M ++ Sbjct: 244 KGPFGCLNRARYGISWGVLGAAEDCWFRARQYGLDRKQFNKPLAGTQLYQKKLADMQTEI 303 Query: 331 ELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKL 390 L + R D G+ SI K A +A A + GGNG EY V + Sbjct: 304 ALGIQASLRVGRLFDEGKMAPEMISIVKRNNCGKALDIARQARDMHGGNGIQIEYHVMRH 363 Query: 391 MRDAKIYQIYEGTSQIQRLIVAR 413 ++ + YEGT + LI+ R Sbjct: 364 AQNLETVNTYEGTHDVHALILGR 386 >1SIR-A nrPDB Length = 394 Score = 371 bits (954), Expect = e-103, Method: Composition-based stats. Identities = 106/385 (27%), Positives = 182/385 (47%), Gaps = 12/385 (3%) Query: 32 EPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHI 91 + L + T + + T R + +E ++P ++ + +I ELG++ I Sbjct: 7 QDPLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI 66 Query: 92 PENCGGLGLGTFDACLISEELAYGCTGVQTAIE-GNSLGQMPIIIAGNDQQKKKYLGRMT 150 + G G+ + L++ EL +G ++A+ +SL PI G+++Q++KYL ++ Sbjct: 67 -KGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLA 125 Query: 151 EEPLMCAYCVTEPGAGSDVAGIKTKAE--KKGDEYIINGQKMWITNGGKANWYFLLARSD 208 + L+ + +TEP +GSD + ++T+A Y +NG K WITN A+ + + AR + Sbjct: 126 KGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCE 185 Query: 209 PDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGA 268 GF++E G+ R + R S T I+ + V+VP+ENVL G + Sbjct: 186 D-------GCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGA-S 237 Query: 269 GFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAM 328 G + R +A G +G ++ L A +YAL+R FG L +Q I LA+M Sbjct: 238 SLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLT 297 Query: 329 KVELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVE 388 ++ L + + D + S+ K A +A A +LGGNG + EY V Sbjct: 298 EITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVI 357 Query: 389 KLMRDAKIYQIYEGTSQIQRLIVAR 413 + + + YEGT I LI+ R Sbjct: 358 RHAMNLEAVNTYEGTHDIHALILGR 382 >5ZW7-A nrPDB Length = 402 Score = 371 bits (952), Expect = e-103, Method: Composition-based stats. Identities = 99/382 (25%), Positives = 180/382 (47%), Gaps = 6/382 (1%) Query: 37 FSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCG 96 F + Q + +A +FA + + A L ++A G + + G Sbjct: 1 MDFNLSNSQSDIYESAYRFACDVLDQDAQTRISQKILSTELWKKAAAYGFAHGPVSHQFG 60 Query: 97 GLGLGTFDACLISEELAYG--CTGVQTAIEGNSLGQ-MPIIIAGNDQQKKKYLGRMTEEP 153 G LG D L+ E L G G+ ++ + +P+ G+ + K KYL + Sbjct: 61 GSELGALDTALMIEALGKGSRDIGLSFSLCAHLCACVIPLYRFGSSELKDKYLESLVTGK 120 Query: 154 LMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKA 213 L+ A TEP AGSD+ ++ A+ YI+NG+K++ITN A+ + + A+++PD Sbjct: 121 LIAANAATEPDAGSDIYNMQATAQPCEGGYILNGKKIFITNAPIADVFIIYAKTNPD--- 177 Query: 214 PANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVA 273 + F++E TPG+ +G IVF D+ +P+ + +GAG + Sbjct: 178 HGFLGVSAFLIEKGTPGLNVGEVIPKDCLSNCPWSEIVFNDIFIPQSQRIGMEGAGGAIF 237 Query: 274 MGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELA 333 + + ++A VG R L+ +YA R+ FGK + + Q++S + +M +++E Sbjct: 238 HDSMIWEKGCLSALFVGGLARLLETTLEYAKARQQFGKAIGQFQSVSNRIIDMKLRLEQC 297 Query: 334 RMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRD 393 R+ RA W+ D G+ +++K + A Q DA+Q GG + E + + + + Sbjct: 298 RLMLYRACWKHDQGQDAEADIAMSKLLISEYAVQSGLDAIQTFGGAAMDQELGLVRHLLN 357 Query: 394 AKIYQIYEGTSQIQRLIVAREH 415 +I+ GT+ IQ+ I+AR+ Sbjct: 358 MIPSRIFSGTNDIQKEIIARKL 379 >3R7K-A nrPDB Length = 403 Score = 371 bits (952), Expect = e-103, Method: Composition-based stats. Identities = 127/378 (33%), Positives = 199/378 (52%), Gaps = 6/378 (1%) Query: 40 EFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLG 99 T +++ AR F EI P AE++ GE P L A E+GL+ PE GG G Sbjct: 28 WTTPERRALSQMARSFVEREIAPKLAEWEHVGEIPRDLHLNAAEVGLLGIGFPEEVGGSG 87 Query: 100 LGTFDACLISEEL--AYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCA 157 D+ L++E + A G TGV A+ + + I G+D ++Y+ ++ + Sbjct: 88 GNAIDSALVTEAILAAGGSTGVCAALFTHGIALPHIAANGSDALIERYVRPTLAGKMIGS 147 Query: 158 YCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANK 217 VTEPGAGSDVA ++T+A ++GD Y++NG K +IT+G +A++ R+ P Sbjct: 148 LGVTEPGAGSDVANLRTRAVREGDTYVVNGAKTFITSGVRADFVTTAVRT----GGPGYG 203 Query: 218 AFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAF 277 + +++ ++PG ++ R+ MG RCSDT + F DV+VP +N++ + +GF M F Sbjct: 204 GVSLLVIDKNSPGFEVSRRLDKMGWRCSDTAELSFVDVRVPADNLVGAENSGFLQIMQQF 263 Query: 278 DKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSY 337 R +A A A RALD A +A ER+TFG+ L Q I LAEMA +V++A Sbjct: 264 QAERLGIAVQAYATAGRALDLAKSWARERETFGRPLTGRQIIRHKLAEMARQVDVACTYT 323 Query: 338 QRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIY 397 + +G S+AK A + + +AVQI GG G+ E +E+ RD +I Sbjct: 324 RAVMQRWLAGEDVVAEVSMAKNTAVYACDYVVNEAVQIFGGMGYMRESEIERHYRDCRIL 383 Query: 398 QIYEGTSQIQRLIVAREH 415 I GT++I ++A+ Sbjct: 384 GIGGGTNEIMNEVIAKRI 401 >3B96-A nrPDB Length = 587 Score = 364 bits (934), Expect = e-101, Method: Composition-based stats. Identities = 126/394 (31%), Positives = 193/394 (48%), Gaps = 9/394 (2%) Query: 34 GLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPE 93 + E T+ KE +F E P A+ D + ELG +P Sbjct: 23 PSVLNEEQTQFLKELVEPVSRFFEEVNDP--AKNDALEMVEETTWQGLKELGAFGLQVPS 80 Query: 94 NCGGLGLGTFDACLISEELAYGCTGVQTAIEGN-SLGQMPIIIAGNDQQKKKYLGRMTEE 152 GG+GL + E + GV + + S+G I++ G QK+KYL ++ Sbjct: 81 ELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASG 140 Query: 153 PLMCAYCVTEPGAGSDVAGIKTKAEKK--GDEYIINGQKMWITNGGKANWYFLLARSDPD 210 + A+C+TEP +GSD A I+T A G Y +NG K+WI+NGG A+ + + A++ Sbjct: 141 ETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVT 200 Query: 211 PKAPA--NKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGA 268 A + T F+VE GI G E MG + S+T + F+ V+VP ENVL G+ Sbjct: 201 DPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGS 260 Query: 269 GFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAM 328 GFKVAM + R +AA G + + +A +A R FG+ + I LA M M Sbjct: 261 GFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVM 320 Query: 329 KVELARMSYQRAAWEVDSGR-RNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPV 387 + + +D G A+I+K F + A ++ + +QI+GG GF E V Sbjct: 321 LQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGV 380 Query: 388 EKLMRDAKIYQIYEGTSQIQRLIVAREH-IDKYK 420 E+++RD +I++I+EGT+ I RL VA + +DK K Sbjct: 381 ERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGK 414 >2IX5-A nrPDB Length = 436 Score = 362 bits (930), Expect = e-100, Method: Composition-based stats. Identities = 104/386 (26%), Positives = 173/386 (44%), Gaps = 9/386 (2%) Query: 30 QREPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNT 89 F+ T +++ + R+ +E+ P+ EY + E+P + + +G+ Sbjct: 44 CTSDYYHFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGG 103 Query: 90 HIPENCGGLGLGTFDACLISEELAYGCTGVQ-TAIEGNSLGQMPIIIAGNDQQKKKYLGR 148 I + G GL + + E+A + +SLG + I + G++ QK+KYL Sbjct: 104 SI-KGYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPS 162 Query: 149 MTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSD 208 + + + + +TEP GSD +G+ T A K + INGQK WI N A+ + AR Sbjct: 163 LAQLNTVACWALTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFAR-- 220 Query: 209 PDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGA 268 GFIV+ D PG++ + +G R I+ ++V VP E+ L G + Sbjct: 221 ----NTTTNQINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNS 276 Query: 269 GFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAM 328 F+ +R +VA +G++ D +Y ERK FG L Q L +M Sbjct: 277 -FQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLG 335 Query: 329 KVELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVE 388 V+ + R ++G+ AS+ KA+ A + A+ ++LGGNG ++ V Sbjct: 336 NVQAMFLMGWRLCKLYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVA 395 Query: 389 KLMRDAKIYQIYEGTSQIQRLIVARE 414 K D + YEGT I L+ RE Sbjct: 396 KAFCDLEPIYTYEGTYDINTLVTGRE 421 >3SWO-A nrPDB Length = 399 Score = 361 bits (926), Expect = e-100, Method: Composition-based stats. Identities = 96/379 (25%), Positives = 169/379 (44%), Gaps = 11/379 (2%) Query: 41 FTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGL 100 + +++ AT R+F + P + ++ P L + LG++ H+ + G G Sbjct: 26 LDQDERDIAATVRQFVDTRLKPNVEGWFESATLPSELAKEFGNLGVLGMHL-QGYGCAGT 84 Query: 101 GTFDACLISEELAYGCTGVQTAIEGN-SLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYC 159 L EL G +G ++ + SL I G+++QK ++L R+ + + Sbjct: 85 NAVSYGLACMELEAGDSGFRSFVSVQGSLSMFSIYRYGSEEQKNEWLPRLAAGDAIGCFG 144 Query: 160 VTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAF 219 +TEP GS+ AG++T+A + G ++I+NG KMWITNG A+ + A++D Sbjct: 145 LTEPDFGSNPAGMRTRARRDGSDWILNGTKMWITNGNLADVATVWAQTDD--------GI 196 Query: 220 TGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDK 279 GF+V DTPG + R S T +V ++V++P L G + ++ Sbjct: 197 RGFLVPTDTPGFTANEIHRKLSLRASVTSELVLDNVRLPASAQL-PLAEGLSAPLSCLNE 255 Query: 280 TRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQR 339 R + GA+G A+ +L+ Y R+ F K L +Q LA M +++ + Sbjct: 256 ARFGIVFGALGAARDSLETTIAYTQSREVFDKPLSNYQLTQEKLANMTVELGKGMLLAIH 315 Query: 340 AAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQI 399 D+ S+ K A +A + +LGG+G EY + + + Sbjct: 316 LGRIKDAEGVRPEQISLGKLNNVREAIAIARECRTLLGGSGITLEYSPLRHANNLESVLT 375 Query: 400 YEGTSQIQRLIVAREHIDK 418 YEGTS++ L + + K Sbjct: 376 YEGTSEMHLLSIGKALTGK 394 >6CY8-B nrPDB Length = 380 Score = 360 bits (925), Expect = e-100, Method: Composition-based stats. Identities = 105/380 (27%), Positives = 179/380 (47%), Gaps = 12/380 (3%) Query: 37 FSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCG 96 +FE+T +Q E A +F +E P+ + +P + G IPE Sbjct: 1 MNFEWTHEQAELFEHALRFGKELSAPL----QEDNGFPRDNWNALGDFGYFGLPIPEKYA 56 Query: 97 --GLGLGTFDACLISEELAYGCTGVQTAIEGNSL---GQMPIIIAGNDQQKKKYLGRMTE 151 G G I E L CT G + MPI+ G++ K + L + Sbjct: 57 KDGSGFDILTTIKIIEGLGQSCTDTGLLFAGAAHTFACSMPILEHGSETLKHQLLPDLAT 116 Query: 152 EPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDP 211 + A ++E AGSD++ + T A+K+GD Y++NG K ++TNG A++Y + A ++ Sbjct: 117 GRKIAANAISEASAGSDISNLATTAQKEGDYYVLNGGKSYVTNGSIADYYVVYATTN--- 173 Query: 212 KAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFK 271 K T F+V +TPGI +G +G R + + F++ + K+ L +G G + Sbjct: 174 KKHGYLGQTAFVVPRNTPGISVGNDYHKLGLRSAPLNQVFFDNCTIHKDYALGREGQGAR 233 Query: 272 VAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVE 331 + + D R + A VG QR L++ +YA R K + QA+S +A+M +++E Sbjct: 234 IFAASMDWERCCLFAIFVGAMQRDLNQCIEYANTRMQGDKTISRFQAVSHRIADMGVRLE 293 Query: 332 LARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLM 391 AR+ AAW+ NT +++K + Q D++++ G G+ E V + Sbjct: 294 SARLMLYYAAWQKSQDVDNTKAVAMSKLAISEAFVQSGIDSIRVHGALGYLDEGRVNNSI 353 Query: 392 RDAKIYQIYEGTSQIQRLIV 411 +DA ++ GTS IQR ++ Sbjct: 354 KDALGSVLFSGTSDIQRELI 373 >5IDU-A nrPDB Length = 410 Score = 360 bits (924), Expect = e-100, Method: Composition-based stats. Identities = 132/383 (34%), Positives = 206/383 (53%), Gaps = 10/383 (2%) Query: 41 FTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIP-ENCGGLG 99 F + +E A +A + + V ++D T L+R E G + + GG G Sbjct: 26 FEARHRELAAGIEAWATQHLACV--QHDDTDTTCRKLVRALGEAGWLKYGVGGAQYGGHG 83 Query: 100 --LGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCA 157 + T CL+ E LA A+ LG I +AG +QK +YL R+++ + A Sbjct: 84 DTIDTRAVCLLRETLANHDGLADFALAMQGLGSGAITLAGTHEQKIRYLPRVSKGEAIAA 143 Query: 158 YCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANK 217 + ++EP AGSDVA + +A +GD Y+I+G K WI+NGG A++Y + AR+ +AP + Sbjct: 144 FALSEPDAGSDVAAMSLQARAEGDCYVIDGDKTWISNGGIADFYVVFART---GEAPGAR 200 Query: 218 AFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAF 277 + FIV+ADTPG+QI + + + F+ +VP+ +L G GFK+AM Sbjct: 201 GISAFIVDADTPGLQIAERIDVIAPH--PLARLHFDSARVPRSQMLGAPGEGFKIAMRTL 258 Query: 278 DKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSY 337 D R VAA ++G A+RAL E A RK FG+ L + Q LA+MA+ ++ + + Sbjct: 259 DVFRTSVAAASLGFARRALQEGLARAASRKMFGQTLGDFQLTQTKLAQMALTIDSSALLV 318 Query: 338 QRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIY 397 RAAW D G T A++AK A + A Q+ AVQ+ GG G + VE+L R+ + Sbjct: 319 YRAAWLRDQGENVTREAAMAKWHASEGAQQVIDAAVQLWGGMGVQSGTTVERLYREIRAL 378 Query: 398 QIYEGTSQIQRLIVAREHIDKYK 420 +IYEG +++Q+LIV R+ + + Sbjct: 379 RIYEGATEVQQLIVGRDLLKAHA 401 >3P4T-A nrPDB Length = 403 Score = 354 bits (909), Expect = 4e-98, Method: Composition-based stats. Identities = 126/393 (32%), Positives = 197/393 (50%), Gaps = 7/393 (1%) Query: 26 KANRQREPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELG 85 Q + S T +++ + T R FA E++P A E+++ GE P L R+A ELG Sbjct: 11 TLEAQTQGPGSMSIWTTAEREALRKTVRAFAEREVLPHAHEWERAGEIPRELHRKAAELG 70 Query: 86 LMNTHIPENCGGLGLGTFDACLISEELAYGCT--GVQTAIEGNSLGQMPIIIAGNDQQKK 143 L+ PE+ GG G D +I EE+ Y + GV ++ + +I +G+ + Sbjct: 71 LLGAGFPEDAGGSGGDGADPVVICEEMHYAGSPGGVYASLFTCGIAVPHMIASGDQRLID 130 Query: 144 KYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFL 203 Y+ + A +TEPG GSDV ++T+A+ GD Y+ING K +IT+G +A++ Sbjct: 131 TYVRPTLRGEKIGALAITEPGGGSDVGHLRTRADLDGDHYVINGAKTYITSGVRADYVVT 190 Query: 204 LARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVL 263 AR+ P + +V+ TPG ++ RK MG R SDT + + DV+VP N++ Sbjct: 191 AART----GGPGAGGVSLIVVDKGTPGFEVTRKLDKMGWRSSDTAELSYTDVRVPVANLV 246 Query: 264 IGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFML 323 + GF AF R +A A AQR LD ++ R TFG+ L+ QA+ L Sbjct: 247 GSENTGFAQIAAAFVAERVGLATQAYAGAQRCLDLTVEWCRNRDTFGRPLISRQAVQNTL 306 Query: 324 AEMAMKVELARMSYQRAAWEVDSGRRNT-YYASIAKAFAGDIANQLATDAVQILGGNGFN 382 A MA ++++AR+ + +G N AK A + +A AVQ+ GG G+ Sbjct: 307 AGMARRIDVARVYTRHVVERQLAGETNLIAEVCFAKNTAVEAGEWVANQAVQLFGGMGYM 366 Query: 383 TEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREH 415 E VE+ RD +I I GT++I + A+ Sbjct: 367 AESEVERQYRDMRILGIGGGTTEILTSLAAKTL 399 >5AHS-A nrPDB Length = 401 Score = 348 bits (892), Expect = 3e-96, Method: Composition-based stats. Identities = 120/382 (31%), Positives = 201/382 (52%), Gaps = 4/382 (1%) Query: 39 FEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGL 98 +E T +Q+ Q AR+ A+ A + D T +YP + + + G M +P + GG Sbjct: 2 YELTPEQRTLQTQARELAQSVFASTAVQTDLTEQYPWDNVAQLRDAGFMGMMLPTSVGGR 61 Query: 99 GLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAY 158 GL T D ++ EE+A C + ++LG + I +++ K + A Sbjct: 62 GLSTLDTVIVIEEMAKACATMGRITVDSNLGAIGAITKYGSEEQIKLAADLVLAGDKPAI 121 Query: 159 CVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKA 218 C++EP AGS + + T+A+K GD YI+NG+K WIT GG + + + AR D A Sbjct: 122 CISEPNAGSAASEMTTRADKNGDHYILNGEKYWITGGGVSKLHLIFARVFDDGVEQGIGA 181 Query: 219 FTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLI---GDGAGFKVAMG 275 F + + G+++GR+ MG R + F D+K+ K ++ G GF M Sbjct: 182 FITVLDDHGPEGLKVGRRLYAMGVRGIPETHLEFHDLKIHKSMMITFPDGLKRGFAALMS 241 Query: 276 AFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARM 335 A++ R A A+G+AQ A +E Y R+ FG+ L E Q + +M+A+M++++E AR+ Sbjct: 242 AYNAQRVGAGAVALGIAQCAFEEGVAYLKRREQFGRPLAEFQGLQWMVADMSVQLEAARL 301 Query: 336 SYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAK 395 + AA ++ + A+ AK FA + AN++ DA+Q G +G+ P+E+ +RDA+ Sbjct: 302 MLRSAAVSGET-FPDINKAAQAKIFAAETANKVTNDALQFFGSSGYGRHNPMERHVRDAR 360 Query: 396 IYQIYEGTSQIQRLIVAREHID 417 ++ I GT+QI R VA + +D Sbjct: 361 MFTIAGGTAQILRTQVASKILD 382 >5JSC-A nrPDB Length = 410 Score = 330 bits (846), Expect = 7e-91, Method: Composition-based stats. Identities = 121/380 (31%), Positives = 192/380 (50%), Gaps = 10/380 (2%) Query: 41 FTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGL 100 F + +E A + R + +++ L+R G + + G Sbjct: 26 FEPRHRELAAGIEAWCRANLA--HEDHEDVDATCRRLVRELGAAGWLKYGVGGVAYGGHG 83 Query: 101 GTFDA---CLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCA 157 T D CL+ E LA A+ LG I + G +QK +YL R+ + A Sbjct: 84 DTIDTRAVCLLRETLAKHSGLADFALAMQGLGSGAISLGGTHEQKTRYLPRVANGTAIAA 143 Query: 158 YCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANK 217 + ++EP AGSDVA + A + GD Y+++G K WI+NGG A++Y + AR+ +AP + Sbjct: 144 FALSEPEAGSDVAAMTLSAREDGDAYVLDGDKTWISNGGIADFYVVFART---GEAPGAR 200 Query: 218 AFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAF 277 + F+V+ADTPG++I + + + F +VP+ +L G GFK+AM Sbjct: 201 GISAFVVDADTPGLEIAERIDVIAPH--PLARLHFAGARVPRSQMLGAPGEGFKLAMRTL 258 Query: 278 DKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSY 337 D R VAA ++G A+ A+ E A RK FG+ L + Q LA+MA+ ++ + + Sbjct: 259 DIFRTSVAAASLGFARHAMAEGVARAASRKMFGQTLGDFQLTQAKLAQMALTIDSSALLV 318 Query: 338 QRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIY 397 RAAW D G T A++AK A + A Q+ AVQ+ GG G + VE L R+ + Sbjct: 319 YRAAWLRDQGENVTREAAMAKWHASEGAQQVIDAAVQLYGGMGVQSGTAVEMLYREIRAL 378 Query: 398 QIYEGTSQIQRLIVAREHID 417 +IYEG +++Q+LIV R+ + Sbjct: 379 RIYEGATEVQQLIVGRDLLK 398 >4HR3-A nrPDB Length = 415 Score = 312 bits (800), Expect = 2e-85, Method: Composition-based stats. Identities = 112/415 (26%), Positives = 190/415 (45%), Gaps = 26/415 (6%) Query: 32 EPGLGFSFEFTEQQKEFQATARKFAREEIIPV----AAEYDK---------TGEYPVP-- 76 PG F + + E A R+F E++PV A +D+ + VP Sbjct: 1 GPG-SMDFAPSARAAELIAAVREFIDAEVMPVERAVLAHHDELLGARAGTTAELWHVPPE 59 Query: 77 ---LIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGC-TGVQTAIEGNSLGQMP 132 L +A GL N +P+ G GL + ++E++ G M Sbjct: 60 LDSLKAKARAAGLWNLFLPDPELGGGLSNSEYAPLAEQMGRSLFAPTVFNCNAPDSGNME 119 Query: 133 II-IAGNDQQKKKYLGRMTEEPLMCAYCVTEPG-AGSDVAGIKTKAEKKGDEYIINGQKM 190 ++ G+ +QK+ +L + E + A+C+TEP A SD + A +GDE +ING+K Sbjct: 120 VLHRYGSQEQKEVWLEPLLEGDIRSAFCMTEPDVASSDATNMAATAVVEGDEVVINGRKW 179 Query: 191 WITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRG- 249 W T G + ++ DP A + +V DTPGI + R MG Sbjct: 180 WSTGVGHPDCKVIIFMGLTDPNAHRYARHSMVLVPMDTPGITVERMLPTMGFYDEPGGHG 239 Query: 250 -IVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKT 308 + F++V++P + + G G GF++A G R A +GLA+ AL+ A + L+R Sbjct: 240 VVSFDNVRLPADAFIAGPGKGFEIAQGRLGPGRVHHAMRLIGLAEVALEHACRRGLDRTA 299 Query: 309 FGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIA--KAFAGDIAN 366 FGK LV +A+ + + R+ AAW +D+ ++++ K A ++A Sbjct: 300 FGKPLVNLGGNRERIADARIAINQTRLLVLHAAWLLDTVGIMGALSAVSEIKVAAPNMAQ 359 Query: 367 QLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDKYKN 421 Q+ A+QI GG G + ++P+ +A+ ++ +G ++ R +VAR + KY N Sbjct: 360 QVIDMAIQIHGGGGLSNDFPLAAAWVNARALRLADGPDEVHRGVVARIELAKYAN 414 >2WBI-A nrPDB Length = 428 Score = 298 bits (764), Expect = 2e-81, Method: Composition-based stats. Identities = 99/408 (24%), Positives = 183/408 (44%), Gaps = 27/408 (6%) Query: 33 PGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEY--------DKTGEYPVPL-IRRAWE 83 G F T + +E + F ++ I+P E + ++ PL I + E Sbjct: 15 DTTGQLFVQTRKGQEVLIKVKHFMKQHILPAEKEVTEFYVQNENSVDKWGKPLVIDKLKE 74 Query: 84 L----GLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQ-TAIEGNSLGQMPII-IAG 137 + GL N +P GL D LI+EE + G M ++ + G Sbjct: 75 MAKVEGLWNLFLPAV---SGLSHVDYALIAEETGKCFFAPDVFNCQAPDTGNMEVLHLYG 131 Query: 138 NDQQKKKYLGRMTEEPLMCAYCVTEPG-AGSDVAGIKTKAEKKGDEYIINGQKMWITNG- 195 +++QKK++L + + + +C+TEP A SD I+ ++ D Y+ING+K W + Sbjct: 132 SEEQKKQWLEPLLQGNITSCFCMTEPDVASSDATNIECSIQRDEDSYVINGKKWWSSGAG 191 Query: 196 -GKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCS---DTRGIV 251 K +L R+ + +K + +V +TPG++I R G + I Sbjct: 192 NPKCKIAIVLGRTQ-NTSLSRHKQHSMILVPMNTPGVKIIRPLSVFGYTDNFHGGHFEIH 250 Query: 252 FEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGK 311 F V+VP N+++G+G GF+++ G R VGLA+RAL + A +R F K Sbjct: 251 FNQVRVPATNLILGEGRGFEISQGRLGPGRIHHCMRTVGLAERALQIMCERATQRIAFKK 310 Query: 312 LLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTY--YASIAKAFAGDIANQLA 369 L H+ ++ +AE + +E R+ +AA +D+ ++ K A +++ Sbjct: 311 KLYAHEVVAHWIAESRIAIEKIRLLTLKAAHSMDTLGSAGAKKEIAMIKVAAPRAVSKIV 370 Query: 370 TDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHID 417 A+Q+ GG G + +YP+ + ++ ++ +G ++ +A + Sbjct: 371 DWAIQVCGGAGVSQDYPLANMYAITRVLRLADGPDEVHLSAIATMELR 418 >4RM7-A nrPDB Length = 391 Score = 279 bits (715), Expect = 1e-75, Method: Composition-based stats. Identities = 93/388 (23%), Positives = 165/388 (42%), Gaps = 8/388 (2%) Query: 36 GFSFEFTEQQKEFQATARKFAREEIIPVA-AEYDKTGEYPVPLIRRAWELGLMNTHIPEN 94 + ++ R++ + P + +++ K P +++ +L + Sbjct: 3 AMYDGLSRDEQRLLNHVREYGEKYFTPASISKWRKDQGLPDEVVKAFVDLDFNGFGVIHR 62 Query: 95 CGGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPII-IAGNDQQKKKYLGRMT-EE 152 F L+ EEL+ N L Q+ I+ + Q + Sbjct: 63 RNHRTYDLFAQVLVIEELSRISGAC--LPFQNDLLQLQILEAFASSAQTSPFRTEYQDTG 120 Query: 153 PLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPK 212 L A ++EP AGSD ++T ++GD ++NG KM++ NG A + A Sbjct: 121 RLSYALAISEPEAGSDTRSMRTHVTREGDTLVMNGTKMFVNNGEYAPALLVSA--YDKTG 178 Query: 213 APANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKV 272 F+ ++V GI E +GQ + F++V+V + L G GF Sbjct: 179 DDGEPEFSFWMVPRSAAGI-YAYPEQKIGQSMLPFATVRFDNVEVKESWRLKGSSKGFSQ 237 Query: 273 AMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVEL 332 + R A A+G AQ A+++A +A R+ FG+ + + Q + L EM +K+ Sbjct: 238 LYSLLEYGRVFTCAAALGEAQAAMEDAVAWARGREAFGQRIADLQQVQMKLTEMEVKLTN 297 Query: 333 ARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMR 392 R AA E D G ++ K + A ++A+DA+QILGG G+ E V + + Sbjct: 298 MRNLVYGAAREYDRGEHKRLSVALMKYYVPKAATEVASDAMQILGGRGYIQENRVSSIWQ 357 Query: 393 DAKIYQIYEGTSQIQRLIVAREHIDKYK 420 D + YQ +GT ++ +I A +++YK Sbjct: 358 DCRGYQFADGTDEVMVVIAAPLILEQYK 385 >1R2J-A nrPDB Length = 366 Score = 274 bits (700), Expect = 6e-74, Method: Composition-based stats. Identities = 98/356 (27%), Positives = 171/356 (48%), Gaps = 10/356 (2%) Query: 64 AAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAI 123 AAE+D +GE P L+ R GL+ + GGLGLG+ + + + C+ +++ + Sbjct: 16 AAEWDTSGELPRDLLVRLGADGLLCAEVAAEHGGLGLGSRENGEFTAHVGSLCSSLRSVM 75 Query: 124 EGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEY 183 + + G+ Q+ +L +T L A +E AGSD++ ++T+ GD Sbjct: 76 TSQGMAAWTVQRLGDAGQRATFLKELTSGKL-AAVGFSERQAGSDLSAMRTRVRLDGDTA 134 Query: 184 IINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQR 243 +++G K+W T A+ + + A +V ADTPG+++ R G R Sbjct: 135 VVDGHKVWTTAAAYADHLVVFGLQEDGSGA-------VVVVPADTPGVRVERVPKPSGCR 187 Query: 244 CSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGA-FDKTRPVVAAGAVGLAQRALDEATKY 302 + + + V+VP VL G GA + + A R VA G VG+ + A + Sbjct: 188 AAGHADLHLDQVRVPAGAVLAGSGASLPMLVAASLAYGRKSVAWGCVGILRACRTAAVAH 247 Query: 303 ALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASI-AKAFA 361 A R+ FG+ L +HQ ++ +A++ ++A + A+ D G A+I AK A Sbjct: 248 ARTREQFGRPLGDHQLVAGHIADLWTAEQIAARVCEYASDHWDEGSPEMVPATILAKHVA 307 Query: 362 GDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHID 417 + A A A Q+L G + VE+ RDAK+ +I EG+S++ R+++A+ + Sbjct: 308 AERAAAGAATAAQVLASAGAREGHVVERAYRDAKLMEIIEGSSEMCRVMLAQHALA 363 >4X28-A nrPDB Length = 400 Score = 273 bits (699), Expect = 9e-74, Method: Composition-based stats. Identities = 101/398 (25%), Positives = 172/398 (43%), Gaps = 31/398 (7%) Query: 37 FSFEFTEQQKEFQATARKF--------AREEIIPVAAEYDKTGEYPVPLIRRAWELGLMN 88 +T QQ+E + R + RE + V EY Y I + G + Sbjct: 1 MRISYTPQQEELRRELRSYFATLMTPERREALSSVQGEYGVGNVY-RETIAQMGRDGWLA 59 Query: 89 THIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGR 148 P+ GG G D + ++E A V + NS+ I+ G D+QK+ +L R Sbjct: 60 LGWPKEYGGQGRSAMDQLIFTDEAAIAGAPVPF-LTINSVA-PTIMAYGTDEQKRFFLPR 117 Query: 149 MTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSD 208 + L + +EPGAG+D+A ++T A + GD+Y++NGQKMW + A++ +L R++ Sbjct: 118 IAAGDLHFSIGYSEPGAGTDLANLRTTAVRDGDDYVVNGQKMWTSLIQYADYVWLAVRTN 177 Query: 209 PD-PKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDG 267 P+ A ++ + IV G G DT + DV+VP N + + Sbjct: 178 PESSGAKKHRGISVLIVPTTAEGFSWTPVHTMAG---PDTSATYYSDVRVPVANRVGEEN 234 Query: 268 AGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERK-TFGKLLVEHQAISFMLAEM 326 AG+K+ + R + + A L E ++A K G L++ + + LA + Sbjct: 235 AGWKLVTNQLNHERVALVSPAPIF--GCLREVREWAQNTKDAGGTRLIDSEWVQLNLARV 292 Query: 327 AMKVELARMSYQRAAWE----VDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGN--- 379 K E+ ++ A D+G + AS AK F ++A + +++LG Sbjct: 293 HAKAEVLKLINWELASSQSGPKDAG-PSPADASAAKVFGTELATEAYRLLMEVLGTAATL 351 Query: 380 -----GFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVA 412 G VE++ R I GT+++QR I+ Sbjct: 352 RQNSPGALLRGRVERMHRACLILTFGGGTNEVQRDIIG 389 >2C12-A nrPDB Length = 439 Score = 268 bits (685), Expect = 4e-72, Method: Composition-based stats. Identities = 93/421 (22%), Positives = 178/421 (42%), Gaps = 42/421 (9%) Query: 37 FSFEFTEQQKEFQATARKFAREEIIPVAAEY----DKTGEYP--VPLIRRAWELGLMNTH 90 F+ + Q E + A+ FA + +AEY D+ + P R A GL+ Sbjct: 2 VDFKLSPSQLEARRHAQAFANTVLTKASAEYSTQKDQLSRFQATRPFYREAVRHGLIKAQ 61 Query: 91 IPENCGGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMT 150 +P GG +I EEL I +LG MP+I+ + ++K+L Sbjct: 62 VPIPLGGTMESLVHESIILEELFAVEPATSITIVATALGLMPVILCDSPSLQEKFLKPFI 121 Query: 151 E--EPLMCAYCVTEPGAGSDV-----AGIKTKAEKKGDEYIINGQKMWITNGG-----KA 198 + + +EP ++ G++T A K G+E++I+G+K+W +N G A Sbjct: 122 SGEGEPLASLMHSEPNGTANWLQKGGPGLQTTARKVGNEWVISGEKLWPSNSGGWDYKGA 181 Query: 199 NWYFLLARSDPDPKAPANK------AFTGFIVEADT------PGIQIGRKELNMGQRCSD 246 + ++ R DP P + +V +T QI + G + Sbjct: 182 DLACVVCRVSDDPSKPQDPNVDPATQIAVLLVTRETIANNKKDAYQILGEPELAGHITTS 241 Query: 247 TRGIVFEDVKVPKENVLIGDGAGFKVAMGA-FDKTRPVVAAGAVGLAQRALDEATKYALE 305 F + VP EN+L G + + F + +V A A+G A+ A +EA +A Sbjct: 242 GPHTRFTEFHVPHENLLCTPGLKAQGLVETAFAMSAALVGAMAIGTARAAFEEALVFAKS 301 Query: 306 RKTFG-KLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVD----SGRRNTYYASIAKAF 360 G K ++EHQ+++ L + +++E +R+ +A ++ + A K + Sbjct: 302 DTRGGSKHIIEHQSVADKLIDCKIRLETSRLLVWKAVTTLEDEALEWKVKLEMAMQTKIY 361 Query: 361 AGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTS------QIQRLIVARE 414 D+A + DA++ +G + + +L+ + Y +++G + Q+QR++ + Sbjct: 362 TTDVAVECVIDAMKAVGMKSYAKDMSFPRLLNEVMCYPLFDGGNIGLRRRQMQRVMALED 421 Query: 415 H 415 + Sbjct: 422 Y 422 >3MKH-A nrPDB Length = 438 Score = 251 bits (641), Expect = 4e-67, Method: Composition-based stats. Identities = 106/416 (25%), Positives = 174/416 (41%), Gaps = 36/416 (8%) Query: 35 LGFSFEFTEQQKEFQATARKFAREEIIPVAAEY-DKTGEYP------VPLIRRAWELGLM 87 + F + QK AR AR ++P Y P P A G++ Sbjct: 1 MAIDFHLSASQKGTYQAARSLARNLLMPARQTYLQHPPNSPLRFQSTQPTYAAAVSAGIL 60 Query: 88 NTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLG 147 I GG G ++ ++ EE I LG PI +A Q + Sbjct: 61 KGQISPAHGGTGGTLIESAILVEECYSVEPSAALTIFATGLGLTPINLAAGPQHAEFLAP 120 Query: 148 RMT-EEPLMCAYCVTEPGAGSDV-----AGIKTKAEKKGDEYIINGQKMWITNGGK---- 197 ++ E + + +EPG ++ G +T A +GDE++ING+KMW TN Sbjct: 121 FLSGEGSPLASLVFSEPGGVANALEKGAPGFQTTARLEGDEWVINGEKMWATNCAGWDFK 180 Query: 198 -ANWYFLLARSDPDP----KAPANKAFTGFIVEADTP-----GIQIGRKELNMGQRCSDT 247 + ++ R P + P NK + AD ++ R G Sbjct: 181 GCDLACVVCRDATTPLEEGQDPENKVMIILVTRADLDRNGEGSFEVLRHVATPGHTSVSG 240 Query: 248 RGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERK 307 + + +V+VP +NVL G G KVA GAFD + +V A VGL + A D A K+A E Sbjct: 241 PHVRYTNVRVPTKNVLCPAGQGAKVAFGAFDGSAVLVGAMGVGLMRAAFDAALKFAKEDN 300 Query: 308 TFGK-LLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSG----RRNTYYASIAKAFAG 362 G L+E QA + +L+ + ++ E AR +AA +++G A AK F Sbjct: 301 RGGAVPLLERQAFADLLSGVKIQTEAARALTWKAAHAMENGPGDYDARRELALAAKVFCS 360 Query: 363 DIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDK 418 + A + TD + +G + ++ + P L+ A + I++G + + + R H+ + Sbjct: 361 EAAVKACTDVINAVGISAYDLQRPFSDLLNTAVVLPIFDGGN----VGIRRRHLQQ 412 >5GJ7-A nrPDB Length = 398 Score = 236 bits (603), Expect = 1e-62, Method: Composition-based stats. Identities = 87/369 (23%), Positives = 141/369 (38%), Gaps = 21/369 (5%) Query: 40 EFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLG 99 +E R A+ A E+D+ G++P I G + +P GGLG Sbjct: 12 ALPADVRERLRITRDLAQA-FHERAPEHDRAGDFPFENIEDLKASGYVRWTVPVEYGGLG 70 Query: 100 LGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAG--NDQQKKKYLGRMTEEPLMCA 157 L + + E LA G AI + + + G D+ + + +E + Sbjct: 71 LSLEEMLMHQEVLAKGDGSTALAIGWHVGILLHLRETGAFPDELFRMVCESVVKEGALIN 130 Query: 158 YCVTEPGAGSDVAGIK--TKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPA 215 C TEP GS G K T A K Y I G+K + T W + A + Sbjct: 131 SCATEPATGSPSRGGKPETTAVKVPGGYRITGRKTFSTLSPALTWIMVTATVADEDVVGQ 190 Query: 216 NKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMG 275 F+V + ++I +G R + + IV +DV VP+E V++ G + Sbjct: 191 ------FLVRKED--VEIVETWDTLGMRATGSHDIVLKDVFVPEERVIVIQRPGVQAERR 242 Query: 276 AFDKT-RPVVAAGAVGLAQRALDEATKYALERK--TFGKLLVEHQAISFMLAEMAMKVEL 332 + A +G+A A D A +YA + T + E + L EM +K+ Sbjct: 243 PDGSGWLLHIPACYLGIALAARDFALEYAATYRPNTLPHPIAEVPHVEQKLGEMELKLLA 302 Query: 333 ARMSYQRAAWEVDSGRRNTY-----YASIAKAFAGDIANQLATDAVQILGGNGFNTEYPV 387 AR A D+ K A + ANQ+ A++++GG + P+ Sbjct: 303 ARTLLYDLARRFDAASPEERVKLQPQFGAVKTLATNAANQVVDLAMRVVGGRSLSRALPL 362 Query: 388 EKLMRDAKI 396 E+ RD + Sbjct: 363 ERYYRDVRA 371 >3M9V-A nrPDB Length = 439 Score = 226 bits (577), Expect = 1e-59, Method: Composition-based stats. Identities = 80/358 (22%), Positives = 141/358 (39%), Gaps = 26/358 (7%) Query: 59 EIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLG-TFDACLISEELAYGCT 117 I AAE+D+ G +P + GLM +P GGLG+ +D + +A Sbjct: 37 RIRSTAAEHDRDGTFPTDTFDALRKDGLMGATVPAELGGLGVDRLYDVAVALLAVARADA 96 Query: 118 GVQTAIEGN-SLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKA 176 A+ S G + ++ + L ++ V G + T Sbjct: 97 STALALHMQLSRGLTLGYEWRHGDERARTLAERILRGMVAGDAVVCSGIKDHHTAVTTLR 156 Query: 177 EKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRK 236 ++++G+K ++ + + AR+D P +V DTPG + Sbjct: 157 PDGAGGWLLSGRKTLVSMAPVGTHFVINARTDGTDGPPR---LASPVVTRDTPGFTVLDN 213 Query: 237 ELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFK--VAMGAFDKTRPVVAAGAVGLAQR 294 +G R S T IVF+D +P ++VL+ D G + + + V VG+AQ Sbjct: 214 WDGLGMRASGTVDIVFDDCPIPADHVLMRDPVGARNDAVLAGQTVSSVSVLGVYVGVAQA 273 Query: 295 ALDEATKYALERKTFGKLLVEHQAISFML-AEMAMKVELARMSYQRAAWEVD-------- 345 A D A ALER+ QA + L AE+ ++ R + A D Sbjct: 274 AYDTAVA-ALERRP-----EPPQAAALTLVAEIDSRLYALRATAGSALTAADALSADLSG 327 Query: 346 ----SGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQI 399 GR+ + AK +A ++ +D + ++GG + +P+ +L+RD + + Sbjct: 328 DMDERGRQMMRHFQCAKLAVNRLAPEIVSDCLSLVGGASYTAGHPLARLLRDVQAGRF 385 >4ZYJ-A nrPDB Length = 425 Score = 219 bits (557), Expect = 2e-57, Method: Composition-based stats. Identities = 82/395 (20%), Positives = 140/395 (35%), Gaps = 35/395 (8%) Query: 42 TEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLG 101 T + ++ + + + D+ PV L R + G++ +PE+ GGLG+ Sbjct: 43 TPAGRRLLDLLERYL-PALEAESRDNDREATLPVHLFDRMRKEGVLGATVPEDLGGLGVH 101 Query: 102 TF-DACLISEELAYGCTGVQTAIEGN---SLGQMPIIIAGNDQ---QKKKYLGRMTEEPL 154 + D L +A GV A+ L G + L +M Sbjct: 102 SLHDVALALARIAGRDAGVALALHMQFSRGLTLDFEWRHGAPSTRPLAEDLLRQMGAGEA 161 Query: 155 MCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAP 214 + GA DV G Y +NG+K ++ G A Y + R + +A Sbjct: 162 VIC------GAVKDVRGTTVLTRATDGSYRLNGRKTLVSMAGIATHYVVSTRLE---EAG 212 Query: 215 ANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAM 274 A +V TPG+ + MG R S + IVF+ V ++ VL G + Sbjct: 213 APVRLAAPVVARTTPGLTVLDNWDGMGMRSSGSVDIVFDGCPVDRDRVLPRGEPGVRDDA 272 Query: 275 GAFDKTRPVVAAGA--VGLAQRALDEATKYALERKTFGKLLVEHQAISF---MLAEMAMK 329 +T +A VG+A+ A A R+ G ++ L + Sbjct: 273 ALAGQTVSSIAMLGIYVGIAEAARRIAL--TELRRRGGAPAGVRTTVAEIDARLFALHTA 330 Query: 330 VELARMSYQRAA-----WEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTE 384 V A + R A GR AK + + D + ++GG G++ Sbjct: 331 VASALTTADRLADDLSGDLAARGRAMMTPFQYAKLLVNRHSVGVVDDCLMLVGGAGYSNS 390 Query: 385 YPVEKLMRDAKI------YQIYEGTSQIQRLIVAR 413 +P+ +L RD + Y +G + + + R Sbjct: 391 HPLARLYRDVRAGGFMHPYNFTDGVDYLSEVALGR 425 >4Y9J-A nrPDB Length = 593 Score = 216 bits (550), Expect = 1e-56, Method: Composition-based stats. Identities = 76/329 (23%), Positives = 141/329 (42%), Gaps = 27/329 (8%) Query: 104 DACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEP 163 A L+S +A V+T N G+ + D+ + R + +TE Sbjct: 138 SAGLVSCPMAMTDGAVKTLTSLNLYGKHKLATEAVDRLR----SRDPSKAWTSGQWMTEK 193 Query: 164 GAGSDVAG-IKTKAEK-KGDEYIINGQKMWITNGGKANWYFLLAR-SDPDPKA-PANKAF 219 GSDVAG T A + D Y ++G K W ++ A+ LAR D D A ++ Sbjct: 194 KGGSDVAGGCDTYAVQIDKDTYRLHGYK-WFSSAVDADVALTLARIVDSDGNALEGSRGL 252 Query: 220 TGFIVE-----ADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAM 274 + F+++ + GIQ+ R + +G + T ++ + + G G Sbjct: 253 SLFLLKIRDESGNLNGIQMVRLKNKLGTKQLPTAELLLDGAI---AERIGDQGRGVAGIS 309 Query: 275 GAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELAR 334 + TR A ++G +R + A Y+ +R FG+ + + LA+M + + Sbjct: 310 NMLNITRIHNAVASLGYMRRIISLARDYSTKRVVFGQTQSKWPLHTTTLAKMEVDTRGSM 369 Query: 335 MSYQRAAWEV---DSGRRNTYYASI-------AKAFAGDIANQLATDAVQILGGNGFNTE 384 + AA + ++G+ + A + K +AG A + ++ ++ GG G+ + Sbjct: 370 LLLFEAARLLGLSEAGKSSDVEAMMLRLITPVLKLYAGKQAVPMVSEGIECFGGQGYMED 429 Query: 385 YPVEKLMRDAKIYQIYEGTSQIQRLIVAR 413 + L+RDA++ I+EGT+ + L V R Sbjct: 430 TGLPTLLRDAQVTPIWEGTTNVLSLDVLR 458 >3U33-A nrPDB Length = 541 Score = 214 bits (546), Expect = 5e-56, Method: Composition-based stats. Identities = 66/281 (23%), Positives = 121/281 (43%), Gaps = 26/281 (9%) Query: 146 LGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEK-KGDEYIINGQKMWITNGGKANWYFLL 204 L + L+ +TE GSDV T+AE+ + Y + G K + + +++ + +L Sbjct: 170 LPGGQKRGLLIGMGMTEKQGGSDVMSNTTRAERLEDGSYRLVGHKWFFS-VPQSDAHLVL 228 Query: 205 ARSDPDPKAPANKAFTGFIVEADTP-----GIQIGRKELNMGQRCSDTRGIVFEDVKVPK 259 A++ + F V P I++ R + +G R + + + F+D Sbjct: 229 AQT--------AGGLSCFFVPRFLPDGQRNAIRLERLKDKLGNRSNASCEVEFQDAI--- 277 Query: 260 ENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAI 319 +L +G G ++ + TR A G+ + +RA A +A +R FG L++ + Sbjct: 278 GWLLGLEGEGIRLILKMGGMTRFDCALGSHAMMRRAFSLAIYHAHQRHVFGNPLIQQPLM 337 Query: 320 SFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYA-------SIAKAFAGDIANQLATDA 372 +L+ MA+++E R A D R + A AK +A Sbjct: 338 RHVLSRMALQLEGQTALLFRLARAWDR-RADAKEALWARLFTPAAKFVICKRGMPFVAEA 396 Query: 373 VQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAR 413 +++LGG G+ E + +L R+ + I+EG+ I L V R Sbjct: 397 MEVLGGIGYCEESELPRLYREMPVNSIWEGSGNIMCLDVLR 437 >5EZ3-A nrPDB Length = 573 Score = 212 bits (539), Expect = 3e-55, Method: Composition-based stats. Identities = 88/413 (21%), Positives = 160/413 (38%), Gaps = 60/413 (14%) Query: 39 FEFTEQQKEFQATARKFAREEIIPVAAEYDKTG------EYP---VPLIRRAWELGLMNT 89 F + + ++ + A E+ P +D+ G EY L+RR+ GL ++ Sbjct: 77 FVLSAEAQDLA----RLANTEL-PKLRTHDRQGRRIDLVEYHPAYHALMRRSVAQGLHSS 131 Query: 90 HI---PENCGGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYL 146 P G ++ +L G T + M + + K++ Sbjct: 132 IWEDNPLESGRRHQARAARFYLTAQLEAGHLCPLTMTSASLAALM-----ASPEVYKQWS 186 Query: 147 GRMTEEP-------------LMCAYCVTEPGAGSDVAGIKTKAEKK-GDEYIINGQKMWI 192 + + +TE G+DV T+AE G + + G K ++ Sbjct: 187 PAVLSRKYDFSQKPAFRKQGVTLGMGMTEKQGGTDVRANATRAEPAIGGAWRLTGHKWFM 246 Query: 193 TNGGKANWYFLLARSDPDPKAPANKAFTGFIVEA-----DTPGIQIGRKELNMGQRCSDT 247 + ++ + LA++ + + F++ ++ G R + +G R + + Sbjct: 247 S-APMSDAFLTLAQT--------KEGLSCFLLPRLGEKGESNGFFFQRLKDKLGNRSNAS 297 Query: 248 RGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERK 307 + F+ ++ G G K M TR A + GL + L EA ++ R Sbjct: 298 SEVEFDGAL---GQMIGSPGEGVKTIMDMVTLTRLDCAVASAGLMRSGLAEAVHHSRHRH 354 Query: 308 TFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIA-------KAF 360 FGK LVE + +LA+MA+ V A R A D + A+ A K + Sbjct: 355 VFGKPLVEQPLMQRVLADMALDVAGATALSMRLARAFDMAASDRAEAAFARSMTPVVKYW 414 Query: 361 AGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAR 413 IA L +A++ LGGNG+ + + + R+A + I+EG+ + L VAR Sbjct: 415 VCKIAPALLYEAMECLGGNGYIEDGNLARAYREAPVNAIWEGSGNVMALDVAR 467 >3MXL-A nrPDB Length = 395 Score = 210 bits (536), Expect = 6e-55, Method: Composition-based stats. Identities = 80/354 (22%), Positives = 141/354 (39%), Gaps = 24/354 (6%) Query: 59 EIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLG-TFDACLISEELAYGCT 117 I AA+ D+TG +PV + +LGLM +P GGLGL +D LA Sbjct: 26 RISAEAADRDRTGTFPVEAFEQFAKLGLMGATVPAELGGLGLTRLYDVATALMRLAEADA 85 Query: 118 GVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEP---GAGSDVAGIKT 174 TA+ + + + Q + M E L+ A E GA D G+ T Sbjct: 86 S--TALAWHVQLSRGLTLTYEWQHGTPPVRAMA-ERLLRAMAEGEAAVCGALKDAPGVVT 142 Query: 175 KAEKKG-DEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQI 233 + G ++++G+K+ ++ A +F+ A+ D + +V D PG+ + Sbjct: 143 ELHSDGAGGWLLSGRKVLVSMAPIATHFFVHAQRRDDD---GSVFLAVPVVHRDAPGLTV 199 Query: 234 GRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFK--VAMGAFDKTRPVVAAGAVGL 291 +G R S T +VF+ V + +L G + + + + G+ Sbjct: 200 LDNWDGLGMRASGTLEVVFDRCPVRADELLERGPVGARRDAVLAGQTVSSITMLGIYAGI 259 Query: 292 AQRALDEATKYALER----KTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEV--- 344 AQ A D A + R + + LV + L + V A + A+ ++ Sbjct: 260 AQAARDIAVGFCAGRGGEPRAGARALVA--GLDTRLYALRTTVGAALTNADAASVDLSGD 317 Query: 345 --DSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKI 396 + GRR AK ++A + D + ++GG + +P+ +L RD + Sbjct: 318 PDERGRRMMTPFQYAKMTVNELAPAVVDDCLSLVGGLAYTAGHPLSRLYRDVRA 371 >4X28-D nrPDB Length = 373 Score = 208 bits (529), Expect = 5e-54, Method: Composition-based stats. Identities = 78/393 (19%), Positives = 146/393 (37%), Gaps = 35/393 (8%) Query: 37 FSFEFTEQQKEFQATARKFAREEIIP-VAAEYDK-TGEYPVPLIRRAWELGLMNTHIPEN 94 F TE ++ P E DK + L R+ + G++++ PE+ Sbjct: 1 MDFTTTEAAQDLGGLVDTIVDAVCTPEHQRELDKLEQRFDRELWRKLIDAGILSSAAPES 60 Query: 95 CGGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPL 154 GG G G + + L + V +E L + G+ + ++ + Sbjct: 61 LGGDGFGVLEQVAVLVALGHQLAAVPY-LESVVLAAGALARFGSPELQQGWGVSAVSGDR 119 Query: 155 MCAYCV-TEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKA 213 + + E G G +A G Y + G + + G A+ + + A +D Sbjct: 120 ILTVALDGEMGEG------PVQAAGTGHGYRLTGTRTQVGYGPVADAFLVPAETDS---- 169 Query: 214 PANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIG-DGAGFKV 272 F+V A PG+ + G + KV + G D A + Sbjct: 170 ----GAAVFLVAAGDPGVAVTAL-ATTGLGSV--GHLELNGAKVDAARRVGGTDVAVWLG 222 Query: 273 AMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVEL 332 + +T A +G+ +R L +YA R+ F + + QA+ LA+ + V+ Sbjct: 223 TLSTLSRT-----AFQLGVLERGLQMTAEYARTREQFDRPIGSFQAVGQRLADGYIDVKG 277 Query: 333 ARMSYQRAAWEVDSG--------RRNTYYASIAKAFAGDIANQLATDAVQILGGNGFNTE 384 R++ +AAW V + + A +A + +++A V + GG G +T+ Sbjct: 278 LRLTLTQAAWRVAEDSLASRECPQPADIDVATAGFWAAEAGHRVAHTIVHVHGGVGVDTD 337 Query: 385 YPVEKLMRDAKIYQIYEGTSQIQRLIVAREHID 417 +PV + AK + G + Q + RE + Sbjct: 338 HPVHRYFLAAKQTEFALGGATGQLRRIGRELAE 370 >4XVX-A nrPDB Length = 389 Score = 198 bits (503), Expect = 5e-51, Method: Composition-based stats. Identities = 76/372 (20%), Positives = 144/372 (38%), Gaps = 28/372 (7%) Query: 51 TARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISE 110 A+ F + A E + +P LI G+ + + + Sbjct: 17 LAKAFDERVVAWTA-EAEAQERFPRQLIEHLGVCGVFDAKWATDARPDVGKLVELAFALG 75 Query: 111 ELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMC----AYCVTEPGAG 166 +LA GV ++ +++ + G K YL + ++ + +E G Sbjct: 76 QLASAGIGVGVSLHDSAIAI--LRRFG----KSDYLRDICDQAIRGAAVLCIGASEESGG 129 Query: 167 SDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANK-----AFTG 221 SD+ ++T+ + + + G K +++ A+ ++ARS + A Sbjct: 130 SDLQIVETEIRSRDGGFEVRGVKKFVSLSPIADHIMVVARSVDHDPTSRHGNVAVVAVPA 189 Query: 222 FIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTR 281 V TP ++G L+ C DT VP + ++ G G R Sbjct: 190 AQVSVQTPYRKVGAGPLDTAAVCIDT--------WVPADALVARAGTGLAAISWGLAHER 241 Query: 282 PVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAA 341 +A QRA+ + R+ FG+ L EHQA+ +A++ +V+L R + A Sbjct: 242 MSIAGQIAASCQRAIGITLARMMSRRQFGQTLFEHQALRLRMADLQARVDLLRYALHGIA 301 Query: 342 WEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGGNGFN-TEYPVEKLMRDAKIYQIY 400 + GR A+ K A + ++ ++ + I GG G+ E + K RD K+ ++ Sbjct: 302 ---EQGRLELRTAAAVKVTAARLGEEVISECMHIFGGAGYLVDETTLGKWWRDMKLARVG 358 Query: 401 EGTSQIQRLIVA 412 GT ++ +VA Sbjct: 359 GGTDEVLWELVA 370 >5YS9-A nrPDB Length = 708 Score = 190 bits (482), Expect = 1e-48, Method: Composition-based stats. Identities = 71/361 (19%), Positives = 131/361 (36%), Gaps = 55/361 (15%) Query: 113 AYGCTGVQTAIEGNS-LGQMPIIIAGNDQQKKKYLGRMTEE--PLMCAYCVTEPGAGSDV 169 G + + ++ L I +G +Q ++ + + + +TE G GS+V Sbjct: 112 GIVDMGTRIRLGVHTGLFMGAIRGSGTKEQYDYWVRKGAADVKGFYGCFAMTELGHGSNV 171 Query: 170 AGIKTKAE--KKGDEYIIN-----GQKMWITNGGK-ANWYFLLARSDPDPKAPANKAFTG 221 AG++T A + DE+IIN K WI A AR D K K F Sbjct: 172 AGLETTATYIQDTDEFIINTPNTGATKWWIGGAAHSATHTACFARLLVDGKDYGVKIFVV 231 Query: 222 FIVEAD----TPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIG-----------D 266 + + PGI +G MG+ D I F +V++P++N+L+ Sbjct: 232 QLRDVSSHSLMPGIALGDIGKKMGRDAIDNGWIQFTNVRIPRQNMLMKYAKVSSTGKVSQ 291 Query: 267 GAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKL-------LVEHQAI 319 ++ GA R + A + ++QR + A +YA R+ FG ++++ Sbjct: 292 PPLAQLTYGALIGGRVTMIADSFFVSQRFITIALRYACVRRQFGTTPGQPETKIIDYPYH 351 Query: 320 SFMLAEMAMKVELARMSYQRAAWEVDSG----------------------RRNTYYASIA 357 L + +M+ ++ + D + ++ Sbjct: 352 QRRLLPLLAFTYAMKMAADQSQIQYDQTTDLLQTIDPKDKGALGKAIVDLKELFASSAGL 411 Query: 358 KAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHID 417 KAF + Q GG+G++ + D + +EG + + L + R I Sbjct: 412 KAFTTWTCANIIDQCRQACGGHGYSGYNGFGQAYADWVVQCTWEGDNNVLCLSMGRGLIQ 471 Query: 418 K 418 Sbjct: 472 S 472 >5Y9D-A nrPDB Length = 709 Score = 189 bits (479), Expect = 2e-48, Method: Composition-based stats. Identities = 67/365 (18%), Positives = 133/365 (36%), Gaps = 60/365 (16%) Query: 113 AYGCTGVQTAIE-GNSLGQMPIIIAGNDQQKKKYLGR--MTEEPLMCAYCVTEPGAGSDV 169 +T + N+L I +G +Q K ++ + + + + +TE G GS++ Sbjct: 118 GMVDMSTRTRLSIHNNLFIGSIRGSGTPEQFKYWVKKGAVAVKQFYGCFAMTELGHGSNL 177 Query: 170 AGIKTKA--EKKGDEYIIN-----GQKMWITNGGKANWYFL-LARSDPDPKAPANKAFTG 221 G++T A ++ D++IIN K WI + + + A+ K + F Sbjct: 178 KGLETTATYDQDSDQFIINTPHIGATKWWIGGAAHTSTHCVCFAKLIVHGKDYGTRNFVV 237 Query: 222 FIVEADTP----GIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIG----DGAGF--- 270 + G+ IG MG+ D I F +V++P++N+L+ G Sbjct: 238 PLRNVHDHSLKVGVSIGDIGKKMGRDGVDNGWIQFTNVRIPRQNMLMRYAKVSDTGVVTK 297 Query: 271 ----KVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFG-------KLLVEHQAI 319 ++ GA + R + A + +++R L A +YA R+ FG ++++ Sbjct: 298 PALDQLTYGALIRGRVSMIADSFHVSKRFLTIALRYACVRRQFGTSGDTKETKIIDYPYH 357 Query: 320 SFMLAEMAMKVELARMSYQRAAWEV--------------------------DSGRRNTYY 353 L + +M A D+ Sbjct: 358 QRRLLPLLAYCYAMKMGADEAQKTWIETTDRILALNPNDPAQKNDLEKAVTDTKELFAAS 417 Query: 354 ASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAR 413 A + KAF ++ + Q GG+G++ + D + +EG + + L + R Sbjct: 418 AGM-KAFTTWGCAKIIDECRQACGGHGYSGYNGFGQGYADWVVQCTWEGDNNVLCLSMGR 476 Query: 414 EHIDK 418 + Sbjct: 477 GLVQS 481 >2FON-A nrPDB Length = 683 Score = 184 bits (468), Expect = 5e-47, Method: Composition-based stats. Identities = 69/339 (20%), Positives = 125/339 (36%), Gaps = 46/339 (13%) Query: 125 GNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKA--EKKGDE 182 + I G D+Q++K+L + ++ Y TE G GS+V G++T A + + DE Sbjct: 121 HWGMFIPAIKGQGTDKQQEKWLPLAYKMQIIGCYAQTELGHGSNVQGLETTATFDPQTDE 180 Query: 183 YIIN-----GQKMWITN-GGKANWYFLLARSDPDPKAPANKAFTGFIV----EADTPGIQ 232 ++I+ K W G + + AR D K F + PG+ Sbjct: 181 FVIHSPTLTSSKWWPGGLGKVSTHAVVYARLITDGKDYGVNGFIVQLRSLEDHKPLPGVT 240 Query: 233 IGRKELNMG---QRCSDTRGIVFEDVKVPKENVLIG------DGAGF------KVAMGAF 277 +G + G D + F+ V++P++ +L+ +G ++ G Sbjct: 241 VGDIGMKFGNGAYNSMDNGVLSFDHVRIPRDQMLMRVSQVTKEGKYVQSDIPRQLLYGTM 300 Query: 278 DKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLV--EHQAISFMLAEMAMKVELARM 335 R + A A RA+ AT+Y+ R+ FG E Q I + + + LA Sbjct: 301 VYVRQSIVADASLAMSRAVCIATRYSAVRRQFGSQNGGQETQVIDYKTQQNRLFPLLASA 360 Query: 336 SYQR-----------------AAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGG 378 R AA + + + K+ + ++ GG Sbjct: 361 YAFRFVGEWLKWLYTDVTQRLAANDFSTLPEAHACTAGLKSLTTSATADGIEECRKLCGG 420 Query: 379 NGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHID 417 +G+ + +L YEG + + +L VAR + Sbjct: 421 HGYLCSSGLPELFAVYVPACTYEGDNVVLQLQVARFLMK 459 >1W07-A nrPDB Length = 659 Score = 181 bits (459), Expect = 6e-46, Method: Composition-based stats. Identities = 70/339 (20%), Positives = 126/339 (37%), Gaps = 46/339 (13%) Query: 125 GNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKA--EKKGDE 182 + I G ++Q+KK+L + ++ Y TE G GS+V G++T A + K DE Sbjct: 102 HWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATLDPKTDE 161 Query: 183 YIIN-----GQKMWITN-GGKANWYFLLARSDPDPKAPANKAFTGFIVEADT----PGIQ 232 ++I+ K W G + + AR + K F + + P I Sbjct: 162 FVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNIT 221 Query: 233 IGRKELNMG---QRCSDTRGIVFEDVKVPKENVLI------GDGAGF------KVAMGAF 277 +G MG D ++F+ V++P++ +L+ +G ++ G Sbjct: 222 VGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTM 281 Query: 278 DKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLV--EHQAISFMLAEMAMKVELARM 335 R + A A RA+ AT+Y+ R+ FG E Q I + + + LA Sbjct: 282 VYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASA 341 Query: 336 SYQR-----------------AAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILGG 378 R AA + + + K+ + ++ GG Sbjct: 342 YAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGG 401 Query: 379 NGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHID 417 +G+ + +L YEG + + +L VAR + Sbjct: 402 HGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMK 440 >5K3G-A nrPDB Length = 684 Score = 160 bits (404), Expect = 1e-39, Method: Composition-based stats. Identities = 63/340 (18%), Positives = 128/340 (37%), Gaps = 45/340 (13%) Query: 123 IEGNSLGQMPIIIA-GNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKK-- 179 + + + +P + A +D+Q+ K+L R ++ Y TE G G+++ ++T A Sbjct: 113 MALHGVMFIPALNAQASDEQQAKWLIRALRREIIGTYAQTEMGHGTNLQNLETTATYDIG 172 Query: 180 GDEYIINGQ-----KMWITNGGK-ANWYFLLARSDPDPKAPANKAFTGFIVEADT----P 229 E++++ K W N GK +N+ ++A K F + + T P Sbjct: 173 TQEFVLHTPKITALKWWPGNLGKSSNYAVVVAHMYIKGKNFGPHTFMVPLRDEKTHKPLP 232 Query: 230 GIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIG----DGAG-------FKVAMGAFD 278 GI IG M D + F + ++P+ N+L+ + G K+ A Sbjct: 233 GITIGDIGPKMAYNIVDNGFLGFNNYRIPRTNLLMRHTKVEADGTYIKPPHAKINYSAMV 292 Query: 279 KTRPVVAAGAVGLAQRALDEATKYALERKTFGK--------LLVEHQAISFMLAEMAMKV 330 R + G + AL+ AT+Y+ R+ G+ ++E+Q L + Sbjct: 293 HVRSYMLTGQAIMLSYALNIATRYSAVRRQ-GQIDKNEPEVKVLEYQTQQHRLFPFIARA 351 Query: 331 ELARMSYQRAAWEVDSGRRNTYYASIA------------KAFAGDIANQLATDAVQILGG 378 + + + + +++ K+ + A GG Sbjct: 352 YAFQFAGAETVKLYERVLKEMKSGNVSLMADLHALTSGLKSVVTHQTGEGIEQARMACGG 411 Query: 379 NGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDK 418 +G++ + ++ A YEG + + L +AR + Sbjct: 412 HGYSMASYISEIYGVAIGGCTYEGENMVMLLQLARYLVKS 451 >1IS2-A nrPDB Length = 661 Score = 156 bits (395), Expect = 1e-38, Method: Composition-based stats. Identities = 66/337 (19%), Positives = 120/337 (35%), Gaps = 42/337 (12%) Query: 125 GNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKA--EKKGDE 182 + ++ +Q++++ + Y TE G G+ + G++T A + K E Sbjct: 103 HLGMFLPTLLHQATAEQQERFFMPAWNLEITGTYAQTEMGHGTHLRGLETTATYDPKTQE 162 Query: 183 YIINGQ-----KMWITNGGK-ANWYFLLARSDPDPKAPANKAFTGFIVEADT----PGIQ 232 +I+N K W GK +N +LA+ + AF I E T PGI Sbjct: 163 FILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGIT 222 Query: 233 IGRKELNMGQRCSDTRGIVFEDVKVPKENVLI------GDGAGF-----KVAMGAFDKTR 281 +G G D + ++ ++P+EN+L+ DG K+ G R Sbjct: 223 VGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVR 282 Query: 282 PVVAAGAVGLAQRALDEATKYALERKT------FGKL-LVEHQAISFM----LAEMAMKV 330 + A +A A +Y+ R+ + +++ Q + LA Sbjct: 283 SFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFH 342 Query: 331 ELARMS---YQRAAWEVDSGRRNTYY-----ASIAKAFAGDIANQLATDAVQILGGNGFN 382 + R Y R + G + + KAF AN + GG+G++ Sbjct: 343 FVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYS 402 Query: 383 TEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDKY 419 + + +EG + + L AR + Y Sbjct: 403 HSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMKIY 439 >5K3J-A nrPDB Length = 674 Score = 140 bits (352), Expect = 2e-33, Method: Composition-based stats. Identities = 64/360 (17%), Positives = 124/360 (34%), Gaps = 43/360 (11%) Query: 101 GTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCV 160 + L G G A+ ++L + +D+Q++K+L R ++ Y Sbjct: 91 DNEEESLHLHREVIGYEGHPFALH-DALFIPTLQSQASDEQQEKWLERARRREIIGCYAQ 149 Query: 161 TEPGAGSDVAGIKTKAEKK--GDEYIINGQ-----KMWITNGGK-ANWYFLLARSDPDPK 212 TE G GS++ ++T A E++++ K W GK N+ ++A Sbjct: 150 TELGHGSNLRNLETTAVYDIASQEFVLHTPTTTALKWWPGALGKSCNYALVVAELIIKRN 209 Query: 213 APANKAFTGFIVEADTP----GIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIG--- 265 F + + T G+ +G M +D + +++VP+ N+L+ Sbjct: 210 NYGPHFFMVQLRDEKTHIPLKGVTVGDIGPKMNFNAADNGYLGLNNLRVPRTNLLMRHCK 269 Query: 266 -DGAG-------FKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTF-------G 310 + G K+ K R +A AL A +Y+ R+ Sbjct: 270 VEADGTYVKPPHAKIGYSGMVKIRSQMAMEQGLFLAHALTIAARYSAVRRQGHLDDKQVE 329 Query: 311 KLLVEHQAISFM----LAEMAMKVELAR---MSYQRAAWEVDSGRRNT-----YYASIAK 358 ++++Q LA + Y + +VD G + S K Sbjct: 330 VKVLDYQTQQHRLFPSLARAYAFIFTGFETIHLYSQLLKDVDMGNTSGMADLHALTSGLK 389 Query: 359 AFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDK 418 + + A GG+G++ + + A Y G + + L +AR + Sbjct: 390 SVVAHETGEGIEQARMACGGHGYSMASYISVVYGIAIGGCTYAGENMVMLLQLARYLVKS 449 >5XDD-A nrPDB Length = 414 Score = 139 bits (350), Expect = 2e-33, Method: Composition-based stats. Identities = 73/408 (17%), Positives = 140/408 (34%), Gaps = 47/408 (11%) Query: 21 RSQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRR 80 R+ H ++ RE TE K F+ T R E ++ G P Sbjct: 2 RTIHANSSAVREDHRALDVA-TELAKTFRVTVR------------ERERAGGTPKAERDA 48 Query: 81 AWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQ 140 GL+ I + GGLG E+A + + + + + + Sbjct: 49 IRRSGLLTLLISKERGGLGESWPTVYEAIAEIASADASLGHLFGYHFSNFAYVDLFASPE 108 Query: 141 QKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDE-YIINGQKMWITNGGKAN 199 QK ++ + E +E A V + A D Y ING K + + A+ Sbjct: 109 QKARWYPQAVRERWFLGNASSENNA--HVLDWRVTATPLPDGSYEINGTKAFCSGSADAD 166 Query: 200 WYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPK 259 + A + DP + ++ +D G+Q+ ++G R +D+ + F V V Sbjct: 167 RLLVFAVTSRDPN--GDGRIVAALIPSDRAGVQVNGDWDSLGMRQTDSGSVTFSGVVVYP 224 Query: 260 ENVLIGDGA-------GFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALER-KTFGK 311 + +L G G K ++ +G+A+ AL+EA Y+ + F Sbjct: 225 DELLGTPGQVTDAFASGSKPSLWTPITQLIFTHL-YLGIARGALEEAAHYSRSHSRPF-- 281 Query: 312 LLVEHQ----------AISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTY-------YA 354 L + A++ + AR R + Sbjct: 282 TLAGVEKATEDPYVLAIYGEFAAQLQVAEAGAREVALRVQELWERNHVTPEQRGQLMVQV 341 Query: 355 SIAKAFAGDIANQLATDAVQILGG-NGFNTEYPVEKLMRDAKIYQIYE 401 + AK A + +L + + +G + ++ ++ RDA+ + +++ Sbjct: 342 ASAKIVATRLVIELTSRLYEAMGARAAASRQFGFDRFWRDARTHTLHD 389 >4JEK-A nrPDB Length = 453 Score = 137 bits (345), Expect = 9e-33, Method: Composition-based stats. Identities = 73/411 (17%), Positives = 138/411 (33%), Gaps = 48/411 (11%) Query: 29 RQREPGLGFSFEFTEQQKEFQ----------ATARKFAREEIIPVAAEYDKTGEYPVPLI 78 +Q G F + +++ + A AR A + A E D+ G Sbjct: 28 QQMGRGSEF-MTLSPEKQHVRPRDAADNDPVAVARGLAEKWRA-TAVERDRAGGSATAER 85 Query: 79 RRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGN 138 GL++ +P GG G A + E+A + + I + G+ Sbjct: 86 EDLRASGLLSLLVPREYGGWGADWPTAIEVVREIAAADGSLGHLFGYHLTNAPMIELIGS 145 Query: 139 DQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGD-EYIINGQKMWITNGGK 197 +Q++ ++ + +E S V K A D Y++NG K + + Sbjct: 146 QEQEEHLYTQIAQNNWWTGNASSENN--SHVLDWKVSATPTEDGGYVLNGTKHFCSGAKG 203 Query: 198 ANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKV 257 ++ F+ D +P A + G+ +G R +D+ F +VKV Sbjct: 204 SDLLFVFGVVQDD--SPQQGAIIAAAIPTSRAGVTPNDDWAAIGMRQTDSGSTDFHNVKV 261 Query: 258 PKENVLIGDGAGFKVAMGAFDKTRPVVAAGA---------VGLAQRALDEATKYALERKT 308 + VL + R + A +G+A ALD A +Y + Sbjct: 262 EPDEVLGAPN---AFVLAFIQSERGSLFAPIAQLIFANVYLGIAHGALDAAREYTRTQAR 318 Query: 309 FGKLLVEHQAI----------SFMLA-EMAMKVELARMSYQRAAWEV-------DSGRRN 350 QA F +A + A + W+ D G Sbjct: 319 PWTPAGIQQATEDPYTIRSYGEFTIALQGADAAAREAAHLLQTVWDKGDALTPEDRGEL- 377 Query: 351 TYYASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYE 401 S KA A + A +++ +++G G + Y ++ R+ + + +++ Sbjct: 378 MVKVSGVKALATNAALNISSGVFEVIGARGTHPRYGFDRFWRNVRTHSLHD 428 >2JBS-A nrPDB Length = 422 Score = 99.3 bits (246), Expect = 3e-21, Method: Composition-based stats. Identities = 64/385 (16%), Positives = 124/385 (32%), Gaps = 48/385 (12%) Query: 59 EIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTG 118 +I A ++ P I+ E+GL P+ GGL + D LA C G Sbjct: 50 QIAKNAESAEQLRRVPDENIKLLKEIGLHRAFQPKVYGGLEMSLPDFANCIVTLAGACAG 109 Query: 119 VQTAIEGNSLGQMPIIIAGNDQQKKKYL--GRMTEEPLMCAYCVTEPGAGSDVAGIKTKA 176 A I + Q + +L T + + E Sbjct: 110 TAWAFSLLCTHSHQIAMFSKQLQDEIWLKDPDATASSSIAPFGKVE-------------- 155 Query: 177 EKKGDEYIINGQKMWITNGGKANWYFL-LARSDPDPKAPANKAFTGFIVEADTPGIQIGR 235 + I+NG W + A + + R D D NK ++ ++ +I Sbjct: 156 -EVEGGIILNGDYGWSSGCDHAEYAIVGFNRFDAD----GNKIYSFGVIPRSD--YEIVD 208 Query: 236 KELNMGQRCSDTRGIVFEDVKVP------KENVLIGDGAGF------KVAMGAFD-KTRP 282 + S ++ + +V +P ++++ G AGF K+ + Sbjct: 209 NWYAQAIKSSGSKMLKLVNVFIPEYRISKAKDMMEGKSAGFGLYPDSKIFYTPYRPYFAS 268 Query: 283 VVAAGAVGLAQRALDEATKYALERKTF--GKLLVEHQAISFMLAEMAMKVELARMSY--- 337 +A ++G+A+R ++ + R G + +AE +V AR Sbjct: 269 GFSAVSLGIAERMIEAFKEKQRNRVRAYTGANVGLATPALMRIAESTHQVAAARALLEKT 328 Query: 338 QRAAWEVDSGRRNTYYASIAKA-----FAGDIANQLATDAVQILGGNGFNTEYPVEKLMR 392 + ++A +A + + + G F +++L R Sbjct: 329 WEDHRIHGLNHQYPNKETLAFWRTNQAYAVKMCIEAVDRLMAAAGATSFMDNSELQRLFR 388 Query: 393 DAKIYQIYEGTS-QIQRLIVAREHI 416 DA + + T + I+ RE + Sbjct: 389 DAHMTGAHAYTDYDVCAQILGRELM 413 >2RFQ-A nrPDB Length = 394 Score = 95.8 bits (237), Expect = 3e-20, Method: Composition-based stats. Identities = 67/365 (18%), Positives = 115/365 (31%), Gaps = 45/365 (12%) Query: 60 IIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGV 119 + A E + P ++ E G PE GG ++A C Sbjct: 23 LRERAQETEDLRRIPDDSMKALQETGFFRLLQPEQWGGYQADPVLFYSAVRKIASACGST 82 Query: 120 QTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKK 179 + + + Q+ + G T+ + +Y GAG + Sbjct: 83 GWVSSIIGVHNWHLALFSQQAQEDVW-GNDTDVRISSSYAP--MGAG----------QVV 129 Query: 180 GDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELN 239 Y +NG W + A+W L P K F F++ + +I Sbjct: 130 DGGYTVNGAWAWSSGCDHASWAVL---GGPVIKDGRPVDFVSFLIPRED--YRIDDVWNV 184 Query: 240 MGQRCSDTRGIVFEDVKVPKENVL--------------IGDGAGFKVAMGAFDKTRPVVA 285 +G R + + +V EDV VP VL +K+ G T ++ Sbjct: 185 VGLRGTGSNTVVVEDVFVPTHRVLSFKAMSNLTAPGLERNTAPVYKMPWGTIHPT--TIS 242 Query: 286 AGAVGLAQRALDEATKYA--LERKTF-GKLLVEHQAISFMLAEMAMKVELA-RMSYQRAA 341 A VG+A A D ++ R F G+ + +AE + ++ A R A Sbjct: 243 APIVGMAYGAYDAHVEHQGKRVRAAFAGEKAKDDPFAKVRIAEASSDIDAAWRQLSGNVA 302 Query: 342 WEVD---SGRRNTYY----ASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRDA 394 E +G + A + A A + G P+++ RDA Sbjct: 303 DEYALLVAGEEVPFELRLRARRDQVRATGRAISSIDKLFESSGATALANGTPLQRFWRDA 362 Query: 395 KIYQI 399 ++ Sbjct: 363 HAGRV 367 >3AFF-A nrPDB Length = 394 Score = 93.9 bits (232), Expect = 1e-19, Method: Composition-based stats. Identities = 63/366 (17%), Positives = 118/366 (32%), Gaps = 45/366 (12%) Query: 59 EIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTG 118 EI A + P ++ ++G P+ GGL + LA C Sbjct: 22 EIRDRAQATEDLRRLPDETVKALDDVGFFTLLQPQQWGGLQCDPALFFEATRRLASVCGS 81 Query: 119 VQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEK 178 + + + Q++ + G + +Y GAG Sbjct: 82 TGWVSSIVGVHNWHLALFDQRAQEEVW-GEDPSTRISSSYAP--MGAG----------VV 128 Query: 179 KGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKEL 238 Y++NG W + A+W F+ P K F F++ +I Sbjct: 129 VDGGYLVNGSWNWSSGCDHASWTFV---GGPVIKDGRPVDFGSFLIPRSE--YEIKDVWY 183 Query: 239 NMGQRCSDTRGIVFEDVKVPKENVL--------------IGDGAGFKVAMGAFDKTRPVV 284 +G R + + +V +DV VP+ L +K+ G T + Sbjct: 184 VVGLRGTGSNTLVVKDVFVPRHRFLSYKAMNDHTAGGLATNSAPVYKMPWGTMHPT--TI 241 Query: 285 AAGAVGLAQRALDEATKYA--LERKTF-GKLLVEHQAISFMLAEMAMKVELA-RMSYQRA 340 +A VG+A A ++ R F G+ + +AE A ++ A R Sbjct: 242 SAPIVGMAYGAYAAHVEHQGKRVRAAFAGEKAKDDPFAKVRIAEAASDIDAAWRQLIGNV 301 Query: 341 AW---EVDSGRRNTYY----ASIAKAFAGDIANQLATDAVQILGGNGFNTEYPVEKLMRD 393 + + +G+ + A + A + + G + E P+++ RD Sbjct: 302 SDEYALLAAGKEIPFELRARARRDQVRATGRSIASIDRLFEASGATALSNEAPIQRFWRD 361 Query: 394 AKIYQI 399 A ++ Sbjct: 362 AHAGRV 367 >5LVW-A nrPDB Length = 413 Score = 90.0 bits (222), Expect = 2e-18, Method: Composition-based stats. Identities = 63/378 (16%), Positives = 118/378 (31%), Gaps = 42/378 (11%) Query: 40 EFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLG 99 E E + E KF AE ++ P +R + L ++ GGL Sbjct: 23 ETAELRAELVERVHKFG-PVFADGVAEGERERRLPDATVRAIDQSQLAMLWTAKSYGGLE 81 Query: 100 LGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYC 159 +++ L++ C + + G++ K+ R + + Sbjct: 82 TDVRTMSEVAKVLSHYCPSTSWVVNNVN---------GSNLLASKF-PRAALDEVFGDA- 130 Query: 160 VTEPGAG-SDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKA 218 PGA + V A + Y + G + T +W L+AR + D Sbjct: 131 ---PGAKLASVFAAAGTAVRTPGGYRLTGSWPYGTGILHDDWAILVAR-EVDADGEPVGG 186 Query: 219 FTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGD---------GAG 269 + + D + + +G R + + +V D VP+ V+ G+ G Sbjct: 187 LSMLVPARD---LTVEDTWHTVGMRATGSHTVVLRDTFVPEHRVISGELQRSRESATDLG 243 Query: 270 FKVAMGAFDKT--RPVVAAGAVGLAQRALDEATKYALERKTFGK---LLVEHQAISFMLA 324 V A+ +G Q A + A R + + L Sbjct: 244 LPPLFRTAAIAAMAVVCASVVLGAGQAARALVVEKAPTRGIAPSKYTRQTDSRTFVSSLG 303 Query: 325 EMAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAF--------AGDIANQLATDAVQIL 376 A+ ++ A M RAA +D + ++ A + + + Sbjct: 304 RTALSIDAAEMHVARAATALDDAAYDAVALPDSELLRIRGDVGQAVSLVTTALDELLWAH 363 Query: 377 GGNGFNTEYPVEKLMRDA 394 G F P+++ RDA Sbjct: 364 GAASFAESNPLQRYWRDA 381 >2OR0-A nrPDB Length = 414 Score = 71.9 bits (175), Expect = 5e-13, Method: Composition-based stats. Identities = 55/364 (15%), Positives = 110/364 (30%), Gaps = 39/364 (10%) Query: 54 KFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELA 113 + EEI A + + + G + P GG + + +A Sbjct: 30 EVVAEEIRGQAVQSEADCRLTDAAAGLLRDSGAIRLLQPRLYGGYEVHPREFAETVMGVA 89 Query: 114 YGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIK 173 + + A Q++ + + M S A + Sbjct: 90 ALDGASGWVTGIVGVHPWELAFADPQVQEEIWGED--NDTWMA----------SPYAPMG 137 Query: 174 TKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQI 233 A Y++ G+ + + W FL A A + I+ T + Sbjct: 138 V-ATPVDGGYVLKGRWSFSSGTDHCQWAFLGAMVGDGEGGIATPSSLHVILPR-TDYQIV 195 Query: 234 GRKELNMGQRCSDTRGIVFEDVKVPKENVL--------------IGDGAGFKVAMGAFDK 279 +G R + ++ ++ + VP L F + Sbjct: 196 EDTWDVIGLRGTGSKDLIVDGAFVPGYRTLNAAKVMDGRAQKEAGRPEPLFNMPYSCMFP 255 Query: 280 TRPVVAAGAVGLAQRALDEATKYALERKTF-GKLLVEHQAISFMLAEMAMKVELARMSYQ 338 + A +G+ + AL +R G+ + E + + E A ++ +R+S Sbjct: 256 --LGITAAVIGITEGALACHIAVQKDRVAITGQKIKEDPYVLSAIGESAAEINASRVSLI 313 Query: 339 RAAWEV----DSGRRNT-YYASIAKAFAGDIANQLATDAVQIL---GGNGFNTEYPVEKL 390 A D+G+ T +I + A + A +I GG + + P+++ Sbjct: 314 ETADRFYDKVDAGKEITFEERAIGRRTQIAAAWRAVRAADEIFARAGGGALHYKTPMQRF 373 Query: 391 MRDA 394 RDA Sbjct: 374 WRDA 377 >3HWC-A nrPDB Length = 515 Score = 40.7 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 35/174 (20%), Positives = 59/174 (33%), Gaps = 21/174 (12%) Query: 145 YLGRMTEEPLMCAYCVTEPGA--GSDVAGIKT----KAEKKGDEYIINGQKMWITNGGKA 198 +L + E+ L C +P SD A ++ EK D I+NG K T Sbjct: 138 FLKLLREKDLNCPLNFVDPQTDRSSDAAQARSPNLRIVEKTDDGIIVNGVKAVGTGIAFG 197 Query: 199 NWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQR------CSDTRGI-- 250 ++ + P P + I +TPG+ + +E + S + Sbjct: 198 DYMHIGC--LYRPGIPGEQVIFAAI-PTNTPGVTVFCRESTVKNDPAEHPLASQGDELDS 254 Query: 251 --VFEDVKVPKENV--LIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEAT 300 VF++V +P E V + FD + V A+ + A Sbjct: 255 TTVFDNVFIPWEQVFHIGNPEHAKLYPQRIFDWVHYHILIRQVLRAELIVGLAI 308 >2YYI-A nrPDB Length = 481 Score = 39.2 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 35/172 (20%), Positives = 59/172 (34%), Gaps = 23/172 (13%) Query: 184 IINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQR 243 ++ G +M T A+ + + + F + TPG+ +E +G Sbjct: 176 VVRGARMTATF-PLADEVLIFPSTLLQAGSEKYA--LAFALPTSTPGLHFVCREALVGGD 232 Query: 244 CSDTRGI-----------VFEDVKVPKENVLIGDGA----GFKVAMGAFDKTRPVVAAGA 288 + +F+DV VP E V I A GA + V A Sbjct: 233 SPFDHPLSSRVEEMDCLVIFDDVLVPWERVFILGNVELCNNAYAATGALNHMAHQVVALK 292 Query: 289 VGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRA 340 + L A AL + G + H + +AE+ + +E R + RA Sbjct: 293 TAKTEAFLGVA---ALMAEGIGADVYGH--VQEKIAEIIVYLEAMRAFWTRA 339 >1U8V-A nrPDB Length = 490 Score = 35.3 bits (80), Expect = 0.053, Method: Composition-based stats. Identities = 45/284 (15%), Positives = 89/284 (31%), Gaps = 55/284 (19%) Query: 135 IAGNDQQK--KKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKK-----------GD 181 G + K +YL + E L+ +T+P G+ A+K D Sbjct: 122 KYGTNYHKNFTEYLKYIQENDLIVDGAMTDPKG---DRGLAPSAQKDPDLFLRIVEKRED 178 Query: 182 EYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKEL--- 238 ++ G K T ++ + ++ + +A + A + F +D G+ + Sbjct: 179 GIVVRGAKAHQTGSINSHEHIIMP-TIAMTEADKDYAVS-FACPSDADGLFMIYGRQSCD 236 Query: 239 ----------NMGQRCSDTRG--IVFEDVKVPKENVLIGDGAGFKVAM--GAFDKTRPVV 284 ++G + + +VF++V +P + + + F M R Sbjct: 237 TRKMEEGADIDLGNKQFGGQEALVVFDNVFIPNDRIFLCQEYDFAGMMVERFAGYHRQSY 296 Query: 285 AAGAVGLAQ---RALDEATKYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAA 341 VG+ A A Y G H + L EM + A Sbjct: 297 GGCKVGVGDVVIGAAALAADYN------GAQKASH--VKDKLIEM--THLNETLYCCGIA 346 Query: 342 WEVD-------SGRRNTYYASIAKAFAGDIANQLATDAVQILGG 378 + + + + A++ K ++ A I GG Sbjct: 347 CSAEGYPTAAGNYQIDLLLANVCKQNITRFPYEIVRLAEDIAGG 390 >4G5E-A nrPDB Length = 517 Score = 34.2 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 26/133 (19%), Positives = 45/133 (33%), Gaps = 20/133 (15%) Query: 161 TEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYF--LLARSDPDPKAPANKA 218 + P A G++ EK +++G K T A+W + R P P ++ Sbjct: 162 SNPDAQQRSPGLRV-IEKNDKGIVVSGVKAIGTGVAFADWIHIGVFFR----PGIPGDQI 216 Query: 219 FTGFIVEADTPGIQIG---------RKELNMGQRCSD-TRGIVFEDVKVPKENV--LIGD 266 +TPG+ I E + + + VF++V +P +V L Sbjct: 217 IFAA-TPVNTPGVTIVCRESVVKEDPIEHPLASQGDELDGMTVFDNVFIPWSHVFHLGNP 275 Query: 267 GAGFKVAMGAFDK 279 FD Sbjct: 276 EHAKLYPQRVFDW 288 >4JKZ-A nrPDB Length = 194 Score = 31.1 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 25/136 (18%), Positives = 47/136 (34%), Gaps = 19/136 (13%) Query: 206 RSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQ-----------RCSDTRGIVFED 254 R + +A ++E G+ I G R + ++ ED Sbjct: 14 RRSEKSRVAIVEATRALLLERGFDGLSIEAVAAKAGVGKQTIYRWWPSRHALVADVLLED 73 Query: 255 -----VKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTF 309 ++PK + + D A + + A TR A L +L+ A R+ F Sbjct: 74 ADKILARMPKTDDVTADLASWAGTLAAALTTRRGHAMLKT-LMAASLEHEDTAARLREGF 132 Query: 310 GKLLVEHQAISFMLAE 325 + L+E ++ L + Sbjct: 133 SRPLIE--SVRDRLRD 146 >5VWM-A nrPDB Length = 400 Score = 30.7 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 13/82 (15%), Positives = 28/82 (34%), Gaps = 9/82 (10%) Query: 186 NGQKMWITNGGK-ANWYFLLARSDPDP--------KAPANKAFTGFIVEADTPGIQIGRK 236 +G+K+++T + + R+D DP + + +V+ D + Sbjct: 117 SGEKVYLTLKPAPVDTGIVFCRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHL 176 Query: 237 ELNMGQRCSDTRGIVFEDVKVP 258 M D + +VP Sbjct: 177 LSAMAGLGIDNAYVELSASEVP 198 >4B3K-A nrPDB Length = 479 Score = 30.3 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 22/66 (33%) Query: 40 EFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLG 99 + Q E A FA + E G++P L+ + G++ PE + Sbjct: 227 AYPASQSEADMAAAHFAELWNNDLFMEAAVHGKFPEELVAVLKKDGVLWQSTPEELALIA 286 Query: 100 LGTFDA 105 D Sbjct: 287 ENRVDY 292 >6C9C-A nrPDB Length = 304 Score = 30.3 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 13/82 (15%), Positives = 28/82 (34%), Gaps = 9/82 (10%) Query: 186 NGQKMWITNGGK-ANWYFLLARSDPDP--------KAPANKAFTGFIVEADTPGIQIGRK 236 +G+K+++T + + R+D DP + + +V+ D + Sbjct: 21 SGEKVYLTLKPAPVDTGIVFCRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHL 80 Query: 237 ELNMGQRCSDTRGIVFEDVKVP 258 M D + +VP Sbjct: 81 LSAMAGLGIDNAYVELSASEVP 102 >3DR5-A nrPDB Length = 221 Score = 29.9 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 31/145 (21%), Positives = 45/145 (31%), Gaps = 23/145 (15%) Query: 147 GRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLAR 206 L+ T G GS A T A YI+NG A+ L Sbjct: 37 PDEMTGQLLTTLAATTNGNGSTGAIAITPAAGLVGLYILNG---------LADNTTLTC- 86 Query: 207 SDPDPKAPANKAFTGFIVEAD-TPG---IQIGRKELNMGQRCSDTRGIVFEDV------- 255 DP++ + EA +P + R M + +D+ +VF V Sbjct: 87 --IDPESEHQRQAKALFREAGYSPSRVRFLLSRPLDVMSRLANDSYQLVFGQVSPMDLKA 144 Query: 256 KVPKENVLIGDGAGFKVAMGAFDKT 280 V L+ G +A D T Sbjct: 145 LVDAAWPLLRRGGALVLADALLDGT 169 >2YXE-A nrPDB Length = 215 Score = 29.5 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 11/59 (18%), Positives = 19/59 (32%) Query: 229 PGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAG 287 PG+++ G + T IV ED V + + + +V G Sbjct: 77 PGMKVLEIGTGCGYHAAVTAEIVGEDGLVVSIERIPELAEKAERTLRKLGYDNVIVIVG 135 >2Q3R-A nrPDB Length = 372 Score = 29.5 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 8/26 (30%), Positives = 12/26 (46%) Query: 359 AFAGDIANQLATDAVQILGGNGFNTE 384 A A + D V+I G NG+ + Sbjct: 166 RLAARNAMEAGFDGVEIHGANGYLID 191 >6J5G-A nrPDB Length = 407 Score = 29.5 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 11/39 (28%), Positives = 19/39 (48%) Query: 162 EPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANW 200 EP G VA +T + +K + I+ +K +T G + Sbjct: 144 EPHTGDYVAANETHSGRKTASFTISSEKTILTMGEYGDV 182 >6B1B-A nrPDB Length = 527 Score = 29.5 bits (65), Expect = 3.1, Method: Composition-based stats. Identities = 31/144 (21%), Positives = 53/144 (36%), Gaps = 29/144 (20%) Query: 177 EKKGD-EYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGR 235 EK+ D I++G K+ TN ++ + + SD + + A F+ D G+++ Sbjct: 186 EKETDAGIIVSGAKVVATNSALTHYNMIGSGSDLGSGSDPDFAL-MFVAPMDADGVKLIS 244 Query: 236 K---ELNMGQRCSD------------TRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKT 280 + E+ G S +V ++V +P ENVL FD+ Sbjct: 245 RASYEMVAGATGSPYDYPLSSRFDENDAILVMDNVLIPWENVL---------IYRDFDRC 295 Query: 281 RPVVAAGAVGLA---QRALDEATK 301 R G Q + A K Sbjct: 296 RRWTMEGGFARMYPLQACVRLAVK 319 >4S1V-D nrPDB Length = 332 Score = 29.1 bits (64), Expect = 3.8, Method: Composition-based stats. Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 1/52 (1%) Query: 96 GGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIAGNDQQKKKYLG 147 GGLGLG + G G + A G+ G MPI++ G++ ++K L Sbjct: 137 GGLGLGRTLSGRTLGIWGLGKIGQRIAQFGHVFG-MPILVWGSEASRQKALE 187 >4U3T-A nrPDB Length = 330 Score = 29.1 bits (64), Expect = 4.1, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 23/69 (33%), Gaps = 10/69 (14%) Query: 160 VTEPGA--------GSDVAGIKTKAEK-KGDEYIINGQ-KMWITNGGKANWYFLLARSDP 209 VTEPG G DV A K Y+ N +I N ++A + Sbjct: 233 VTEPGGTGTAGAVDGFDVGAKTGTARKLVNGRYVDNKHVGTFIGFAPAKNPRVIVAVTID 292 Query: 210 DPKAPANKA 218 +P A Sbjct: 293 EPTAHGYYG 301 >4QNW-A nrPDB Length = 392 Score = 28.8 bits (63), Expect = 4.7, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 24/67 (35%), Gaps = 9/67 (13%) Query: 323 LAEMAMKVELARMSYQR-----AAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQILG 377 LA+M + + + + A D ++ + A A D V+I G Sbjct: 119 LADMKDLISSSAVPVEEKGPLPRALTEDEIQQCIADFAQA----ARNAINAGFDGVEIHG 174 Query: 378 GNGFNTE 384 NG+ + Sbjct: 175 ANGYLID 181 >2GG4-A nrPDB Length = 455 Score = 28.8 bits (63), Expect = 4.8, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 17/33 (51%), Gaps = 4/33 (12%) Query: 164 GAGSDVAGIKTKAEKKGDEYIINGQKMWITNGG 196 G + + + K+GD +II+G + NGG Sbjct: 58 NTGKAMQAMGARIRKEGDTWIIDG----VGNGG 86 >5KSH-A nrPDB Length = 540 Score = 28.4 bits (62), Expect = 6.1, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 23/69 (33%), Gaps = 10/69 (14%) Query: 160 VTEPGA--------GSDVAGIK-TKAEKKGDEYIINGQ-KMWITNGGKANWYFLLARSDP 209 VTEPG G DV T + Y+ N +I N ++A + Sbjct: 436 VTEPGGTGTAGAVDGFDVGAKTGTTRKLVNGRYVDNKHVGTFIGFAPAKNPRVIVAVTID 495 Query: 210 DPKAPANKA 218 +P A Sbjct: 496 EPTAHGYYG 504 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.314 0.145 0.396 Lambda K H 0.267 0.0446 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,204,745 Number of Sequences: 36641 Number of extensions: 740192 Number of successful extensions: 2482 Number of sequences better than 10.0: 100 Number of HSP's better than 10.0 without gapping: 147 Number of HSP's successfully gapped in prelim test: 34 Number of HSP's that attempted gapping in prelim test: 1939 Number of HSP's gapped (non-prelim): 189 length of query: 421 length of database: 10,336,785 effective HSP length: 100 effective length of query: 321 effective length of database: 6,672,685 effective search space: 2141931885 effective search space used: 2141931885 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 61 (28.0 bits)