BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P11166 (492 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5EQH-A nrPDB 993 0.0 4ZWB-A nrPDB 644 0.0 4YBQ-A nrPDB 395 e-110 4YB9-D nrPDB 392 e-109 4LDS-A nrPDB 205 4e-53 4GC0-A nrPDB 180 1e-45 6H7D-A nrPDB 159 3e-39 1Z6A-A nrPDB 35 0.076 5HSW-A nrPDB 30 1.8 >5EQH-A nrPDB Length = 492 Score = 993 bits (2568), Expect = 0.0, Method: Compositional matrix adjust. Identities = 492/492 (100%), Positives = 492/492 (100%) Query: 1 MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTT 60 MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTT Sbjct: 1 MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTT 60 Query: 61 LTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFE 120 LTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFE Sbjct: 61 LTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFE 120 Query: 121 MLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIM 180 MLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIM Sbjct: 121 MLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIM 180 Query: 181 GNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHD 240 GNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHD Sbjct: 181 GNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHD 240 Query: 241 LQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEK 300 LQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEK Sbjct: 241 LQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEK 300 Query: 301 AGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQ 360 AGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQ Sbjct: 301 AGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQ 360 Query: 361 LPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM 420 LPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM Sbjct: 361 LPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM 420 Query: 421 CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPE 480 CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPE Sbjct: 421 CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPE 480 Query: 481 ELFHPLGADSQV 492 ELFHPLGADSQV Sbjct: 481 ELFHPLGADSQV 492 >4ZWB-A nrPDB Length = 518 Score = 644 bits (1660), Expect = 0.0, Method: Compositional matrix adjust. Identities = 313/477 (65%), Positives = 385/477 (80%), Gaps = 1/477 (0%) Query: 5 SKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTL 64 ++K+T L+ A+ A +GS QFGYNTGVINAP+K+I+EF +T + LT+L Sbjct: 25 TQKVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFITKTLTDKGNAPPSEVLLTSL 84 Query: 65 WSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLIL 124 WSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSML++NLLA MG K+ KS EMLIL Sbjct: 85 WSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLIL 144 Query: 125 GRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKD 184 GR +IG++CGL TGFVPMY+GE+SPTALRGA GTL+QLGIVVGIL+AQ+FGL+ I+G+++ Sbjct: 145 GRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEE 204 Query: 185 LWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEM 244 LWPLLL +PA+LQ LPFCPESPRFLLINR EE AK +L++L GT DV+ D+QEM Sbjct: 205 LWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEM 264 Query: 245 KEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQ 304 K+ES +M +EK+VT+LELFR +YRQPI+I++VLQLSQQLSGINAVFYYST IF+ AGVQ Sbjct: 265 KDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQ 324 Query: 305 QPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQLPWM 364 +P+YATIG+G+VNT FTVVSLF+VERAGRRTLH+IGL GMA C+ LMT++L L + M Sbjct: 325 EPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGM 384 Query: 365 SYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQY 424 S++ I AI FVAFFE+GPGPIPWFIVAELFSQGPRPAA+AVAG SNWTSNF+VG+ F Sbjct: 385 SFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPS 444 Query: 425 VEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPEE 481 G YVFIIFT L+ F FT+FKVPET+GRTF++I F +G A +D++ ++ Sbjct: 445 AAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF-EGQAHGADRSGKD 500 >4YBQ-A nrPDB Length = 508 Score = 395 bits (1016), Expect = e-110, Method: Compositional matrix adjust. Identities = 208/488 (42%), Positives = 309/488 (63%), Gaps = 8/488 (1%) Query: 1 MEPSSKKLTGRLMLAVGGAVL-----GSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGES 55 ME ++ TG+L L + A S Q+GYN +N+P + +++FY T+ R E+ Sbjct: 1 MEKEDQEKTGKLTLVLALATFLAAFGSSFQYGYNVAAVNSPSEFMQQFYYDTYYDRNKEN 60 Query: 56 ILPTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKL 115 I TLT LWSL+V++F GG IGS VG VN GR+ ++L N+ + + A+LMG SK+ Sbjct: 61 IESFTLTLLWSLTVSMFPFGGFIGSLMVGFLVNNLGRKGALLFNNIFSILPAILMGCSKI 120 Query: 116 GKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFG 175 KSFE++I R ++G+ G+++ VPMY+GE++P LRGALG + QL I VGIL+AQ+FG Sbjct: 121 AKSFEIIIASRLLVGICAGISSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQLFG 180 Query: 176 LDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTA 235 L S++ +++ WP+LL + +PA LQ ++LPF PESPR+LLI + E+ A+ L+ LRG Sbjct: 181 LRSVLASEEGWPILLGLTGVPAGLQLLLLPFFPESPRYLLIQKKNESAAEKALQTLRGWK 240 Query: 236 DVTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYST 295 DV +++E+++E +++ +LFR + R ++ +VL QQLSG+NA++YY+ Sbjct: 241 DVDMEMEEIRKEDEAEKAAGFISVWKLFRMQSLRWQLISTIVLMAGQQLSGVNAIYYYAD 300 Query: 296 SIFEKAGVQQP--VYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTI 353 I+ AGV+ Y T G+G VN T+V++FVVE GRR L LIG + I++T+ Sbjct: 301 QIYLSAGVKSNDVQYVTAGTGAVNVFMTMVTVFVVELWGRRNLLLIGFSTCLTACIVLTV 360 Query: 354 ALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWT 413 ALAL + WM Y+SIV + +V VGP PIP + E+F Q RP+A + G +W Sbjct: 361 ALALQNTISWMPYVSIVCVIVYVIGHAVGPSPIPALFITEIFLQSSRPSAYMIGGSVHWL 420 Query: 414 SNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGAS 473 SNFIVG+ F +++ GPY FIIF ++ +L I+ + VPETKGRTF EI F + Sbjct: 421 SNFIVGLIFPFIQVGLGPYSFIIFAIICLLTTIYIFMVVPETKGRTFVEINQIFAKKN-K 479 Query: 474 QSDKTPEE 481 SD PE+ Sbjct: 480 VSDVYPEK 487 >4YB9-D nrPDB Length = 479 Score = 392 bits (1007), Expect = e-109, Method: Compositional matrix adjust. Identities = 205/471 (43%), Positives = 302/471 (64%), Gaps = 8/471 (1%) Query: 1 MEPSSK-----KLTGRLMLAVGGAVLGS-LQFGYNTGVINAPQKVIEEFYNQTWVHRYGE 54 MEP +LT ++LA A GS Q+GYN IN+P + +++FY T+ R GE Sbjct: 1 MEPQDPVKREGRLTPVIVLATLIAAFGSSFQYGYNVAAINSPSEFMKDFYAYTYYDRVGE 60 Query: 55 SILPTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSK 114 + LT LWS++V++F GG +GS VG VN GR+ ++L N+ + V A+LMGFS+ Sbjct: 61 YMNEFYLTLLWSVTVSMFPFGGFLGSLMVGPLVNNLGRKGTLLFNNIFSIVPALLMGFSE 120 Query: 115 LGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVF 174 L KSFEM+I+ R ++G+ GL++ VPMY+GE++P RGALG + QL I +GIL+AQ+F Sbjct: 121 LAKSFEMIIVARVLVGICAGLSSNVVPMYLGELAPKNWRGALGVVPQLFITIGILVAQIF 180 Query: 175 GLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGT 234 GL S++ N++ WP+LL + IPA+LQ + LPF PESPR+LLI + +E AKS L++LRG Sbjct: 181 GLRSLLANEEGWPILLGLTGIPAVLQLLFLPFFPESPRYLLIQKKDEAAAKSALRRLRGW 240 Query: 235 ADVTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYS 294 DV +++E+ EE R +++L+LF+ + R ++ +VL QQLSG+NA++YY+ Sbjct: 241 HDVDAEIEEILEEDRAEKAVGFISVLKLFKMRSLRWQVISIIVLMAGQQLSGVNAIYYYA 300 Query: 295 TSIFEKAGVQQP--VYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMT 352 I+ AGV + Y T G+G VN TV ++FVVE GRR L L+G + ++T Sbjct: 301 DQIYLSAGVNEDDVQYVTAGTGAVNVLITVCAIFVVELMGRRFLLLLGFSVCFTACCVLT 360 Query: 353 IALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNW 412 ALAL + + WM Y+SI + +V +GP PIP +V E+F Q RPAA VAG +W Sbjct: 361 GALALQDVISWMPYVSIACVISYVIGHALGPSPIPALLVTEIFLQSSRPAAYMVAGTVHW 420 Query: 413 TSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEI 463 SNF VG+ F +++ G Y F+IF V+ +L ++ + +PETK +TF EI Sbjct: 421 LSNFTVGLVFPFIQVGLGAYSFVIFAVICLLTTVYIFLIIPETKSKTFIEI 471 >4LDS-A nrPDB Length = 446 Score = 205 bits (521), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 127/406 (31%), Positives = 233/406 (57%), Gaps = 15/406 (3%) Query: 74 VGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYC 133 +G ++G+ S G ++ GRR ++++ ++ + A+++ S + +LI+GR IIG+ Sbjct: 53 IGAIVGAGSSGPLADKLGRRRLVMLIAIVFIIGALILAAST---NLALLIIGRLIIGLAV 109 Query: 134 GLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSII 193 G + VP+Y+ E++PT RG+LG+L+QL I +GIL A + ++ + + W +L + Sbjct: 110 GGSMSTVPVYLSEMAPTEYRGSLGSLNQLMITIGILAAYL--VNYAFADIEGWRWMLGLA 167 Query: 194 FIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMKEESRQMMR 253 +P+++ + + F PESPR+LL NRNEE A+ V+K +++ +L+EMKE + Sbjct: 168 VVPSVILLVGIYFMPESPRWLLENRNEE-AARQVMKITYDDSEIDKELKEMKE--INAIS 224 Query: 254 EKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQP--VYATI 311 E T++ +SP + +++ + + QQ GINAV +YS+SIF KAG+ + + ++ Sbjct: 225 ESTWTVI---KSPWLGRILIVGCIFAIFQQFIGINAVIFYSSSIFAKAGLGEAASILGSV 281 Query: 312 GSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQLPWMSYLSIVA 371 G G +N T+V++FVV++ R+ L + G GM ++M I + + + +++ IV Sbjct: 282 GIGTINVLVTIVAIFVVDKIDRKKLLVGGNIGMIASLLIMAILIWTI-GIASSAWIIIVC 340 Query: 372 IFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYV-EQLCG 430 + F+ FF + GP+ W ++ ELF R AA ++ IV + F + + L Sbjct: 341 LSLFIVFFGISWGPVLWVMLPELFPMRARGAATGISALVLNIGTLIVSLFFPILSDALST 400 Query: 431 PYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSD 476 +VF+IF + VL IF +PET+GR+ +EI R+ ++++ Sbjct: 401 EWVFLIFAFIGVLAMIFVIKFLPETRGRSLEEIEYELRERTGARTE 446 >4GC0-A nrPDB Length = 491 Score = 180 bits (457), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 136/477 (28%), Positives = 236/477 (49%), Gaps = 47/477 (9%) Query: 19 AVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLWSLSVAIFSVGGMI 78 A LG L FGY+T VI+ + + + +++ + +L VA +G +I Sbjct: 17 ATLGGLLFGYDTAVISGTVESLNTVFVAP------QNLSESAANSLLGFCVASALIGCII 70 Query: 79 GSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKS---------------FEMLI 123 G G NRFGRR+S+ + +L F+S V + +LG + + Sbjct: 71 GGALGGYCSNRFGRRDSLKIAAVLFFISGVGSAWPELGFTSINPDNTVPVYLAGYVPEFV 130 Query: 124 LGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGL------D 177 + R I G+ GL + PMY+ E++P +RG L + +Q I+ G L+ D Sbjct: 131 IYRIIGGIGVGLASMLSPMYIAELAPAHIRGKLVSFNQFAIIFGQLLVYCVNYFIARSGD 190 Query: 178 SIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADV 237 + N D W + + IPALL ++L PESPR+L+ +R ++ +A+ +L+K+ G Sbjct: 191 ASWLNTDGWRYMFASECIPALLFLMLLYTVPESPRWLM-SRGKQEQAEGILRKIMGNTLA 249 Query: 238 THDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSI 297 T +QE+K K L +F I+I V+L + QQ GIN V YY+ + Sbjct: 250 TQAVQEIKHSLDH--GRKTGGRLLMFGVGV----IVIGVMLSIFQQFVGINVVLYYAPEV 303 Query: 298 FEKAGVQQPV--YATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIAL 355 F+ G + TI G++N FTV+++ V++ GR+ L +IG GMA + ++ Sbjct: 304 FKTLGASTDIALLQTIIVGVINLTFTVLAIMTVDKFGRKPLQIIGALGMA--IGMFSLGT 361 Query: 356 ALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSN 415 A Q P ++++++ +VA F + GP+ W +++E+F R A+A+A + W +N Sbjct: 362 AFYTQAP--GIVALLSMLFYVAAFAMSWGPVCWVLLSEIFPNAIRGKALAIAVAAQWLAN 419 Query: 416 FIVGMCFQYVEQ-------LCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIAS 465 + V F +++ + + I+ + VL +F + VPETKG+T +E+ + Sbjct: 420 YFVSWTFPMMDKNSWLVAHFHNGFSYWIYGCMGVLAALFMWKFVPETKGKTLEELEA 476 >6H7D-A nrPDB Length = 521 Score = 159 bits (401), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 124/475 (26%), Positives = 225/475 (47%), Gaps = 39/475 (8%) Query: 19 AVLGSLQFGYNTGV---INAPQKVIEEFYNQTWV------HRYGESILPTTLTTLWSLSV 69 A +G L FGY+ G+ + + ++ + +F+ Q H + L++ S+ Sbjct: 33 AAMGGLLFGYDLGISGGVTSMEEFLTKFFPQVESQMKKAKHDTAYCKFDNQMLQLFTSSL 92 Query: 70 AIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFII 129 + ++ SF + + GR+ SM + L + A+ F+ + MLI+GR ++ Sbjct: 93 YL---AALVASFMASVITRKHGRKVSMFIGGLAFLIGAL---FNAFAVNVSMLIIGRLLL 146 Query: 130 GVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLL 189 GV G P+Y+ E++P +RGAL Q+ I +GIL+A + + + W + Sbjct: 147 GVGVGFANQSTPVYLSEMAPAKIRGALNIGFQMAITIGILVANLINYGTSKMAQHGWRVS 206 Query: 190 LSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMKE--E 247 L + +PA++ I P++P +L R + AK +LKK+RG +V H+ Q++ + E Sbjct: 207 LGLAAVPAVVMVIGSFILPDTPNSML-ERGKNEEAKQMLKKIRGADNVDHEFQDLIDAVE 265 Query: 248 SRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGV--QQ 305 + + + I+E YR ++ + QQ++GIN + +Y+ +F+ G Sbjct: 266 AAKKVENPWKNIME----SKYRPALIFCSAIPFFQQITGINVIMFYAPVLFKTLGFGDDA 321 Query: 306 PVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILM---------TIALA 356 + + + +G+VN T VS++ V+R GRR L L G M C +L+ T Sbjct: 322 ALMSAVITGVVNMLSTFVSIYAVDRYGRRLLFLEGGIQMFICQLLVGSFIGARFGTSGTG 381 Query: 357 LLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNF 416 L L+ + + +VA F GP+ W + +E+ RPA A+ N F Sbjct: 382 TLTPATADWILAFICV--YVAGFAWSWGPLGWLVPSEICPLEIRPAGQAINVSVNMFFTF 439 Query: 417 IVGMCFQYVEQLCGPY--VFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQ 469 ++G F + LC +F F ++ + +F YF +PETKG +E+ ++Q Sbjct: 440 LIGQFF--LTMLCHMKFGLFYFFASMVAIMTVFIYFLLPETKGVPIEEMGRVWKQ 492 >1Z6A-A nrPDB Length = 500 Score = 35.0 bits (79), Expect = 0.076, Method: Compositional matrix adjust. Identities = 31/122 (25%), Positives = 51/122 (41%), Gaps = 9/122 (7%) Query: 33 INAPQ----KVIEEFYNQTWVHRYGESILPTTLTTLWSLSVAIFSVGGMIGSFS--VGLF 86 I PQ K ++E ++ + G I + LWS + F G++GS+S F Sbjct: 161 IKNPQTKIFKAVKELKSKYRIALTGTPI-ENKVDDLWS--IMTFLNPGLLGSYSEFKSKF 217 Query: 87 VNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGE 146 + ++M L A +S ++ +K K+ + + VYC LT MY E Sbjct: 218 ATPIKKGDNMAKEELKAIISPFILRRTKYDKAIINDLPDKIETNVYCNLTPEQAAMYKAE 277 Query: 147 VS 148 V Sbjct: 278 VE 279 >5HSW-A nrPDB Length = 488 Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust. Identities = 17/53 (32%), Positives = 24/53 (45%), Gaps = 6/53 (11%) Query: 291 FYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVV------ERAGRRTLH 337 +Y +T F K G Q PV TIG ++ + +L +V A R LH Sbjct: 404 YYIATGFFRKRGYQDPVNCTIGGDALDPHVEIPTLLIVTPVYFPRGAKHRLLH 456 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5EQH-A nrPDB 616 e-177 4ZWB-A nrPDB 573 e-164 4YBQ-A nrPDB 564 e-161 4YB9-D nrPDB 552 e-157 6H7D-A nrPDB 440 e-124 4GC0-A nrPDB 437 e-123 4LDS-A nrPDB 392 e-109 Sequences not found previously or not previously below threshold: 4J05-A nrPDB 90 2e-18 4W6V-A nrPDB 37 0.014 6E9N-A nrPDB 36 0.047 6EUQ-A nrPDB 34 0.16 3WDO-A nrPDB 30 2.2 1PW4-A nrPDB 29 4.9 5O7H-B nrPDB 28 8.0 3O8N-A nrPDB 28 8.9 >5EQH-A nrPDB Length = 492 Score = 616 bits (1588), Expect = e-177, Method: Composition-based stats. Identities = 492/492 (100%), Positives = 492/492 (100%) Query: 1 MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTT 60 MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTT Sbjct: 1 MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTT 60 Query: 61 LTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFE 120 LTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFE Sbjct: 61 LTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFE 120 Query: 121 MLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIM 180 MLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIM Sbjct: 121 MLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIM 180 Query: 181 GNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHD 240 GNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHD Sbjct: 181 GNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHD 240 Query: 241 LQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEK 300 LQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEK Sbjct: 241 LQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEK 300 Query: 301 AGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQ 360 AGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQ Sbjct: 301 AGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQ 360 Query: 361 LPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM 420 LPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM Sbjct: 361 LPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM 420 Query: 421 CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPE 480 CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPE Sbjct: 421 CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPE 480 Query: 481 ELFHPLGADSQV 492 ELFHPLGADSQV Sbjct: 481 ELFHPLGADSQV 492 >4ZWB-A nrPDB Length = 518 Score = 573 bits (1478), Expect = e-164, Method: Composition-based stats. Identities = 313/477 (65%), Positives = 385/477 (80%), Gaps = 1/477 (0%) Query: 5 SKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTL 64 ++K+T L+ A+ A +GS QFGYNTGVINAP+K+I+EF +T + LT+L Sbjct: 25 TQKVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFITKTLTDKGNAPPSEVLLTSL 84 Query: 65 WSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLIL 124 WSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSML++NLLA MG K+ KS EMLIL Sbjct: 85 WSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLIL 144 Query: 125 GRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKD 184 GR +IG++CGL TGFVPMY+GE+SPTALRGA GTL+QLGIVVGIL+AQ+FGL+ I+G+++ Sbjct: 145 GRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEE 204 Query: 185 LWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEM 244 LWPLLL +PA+LQ LPFCPESPRFLLINR EE AK +L++L GT DV+ D+QEM Sbjct: 205 LWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEM 264 Query: 245 KEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQ 304 K+ES +M +EK+VT+LELFR +YRQPI+I++VLQLSQQLSGINAVFYYST IF+ AGVQ Sbjct: 265 KDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQ 324 Query: 305 QPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQLPWM 364 +P+YATIG+G+VNT FTVVSLF+VERAGRRTLH+IGL GMA C+ LMT++L L + M Sbjct: 325 EPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGM 384 Query: 365 SYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQY 424 S++ I AI FVAFFE+GPGPIPWFIVAELFSQGPRPAA+AVAG SNWTSNF+VG+ F Sbjct: 385 SFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPS 444 Query: 425 VEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPEE 481 G YVFIIFT L+ F FT+FKVPET+GRTF++I F +G A +D++ ++ Sbjct: 445 AAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF-EGQAHGADRSGKD 500 >4YBQ-A nrPDB Length = 508 Score = 564 bits (1454), Expect = e-161, Method: Composition-based stats. Identities = 208/488 (42%), Positives = 309/488 (63%), Gaps = 8/488 (1%) Query: 1 MEPSSKKLTGRLMLAVGGAVL-----GSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGES 55 ME ++ TG+L L + A S Q+GYN +N+P + +++FY T+ R E+ Sbjct: 1 MEKEDQEKTGKLTLVLALATFLAAFGSSFQYGYNVAAVNSPSEFMQQFYYDTYYDRNKEN 60 Query: 56 ILPTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKL 115 I TLT LWSL+V++F GG IGS VG VN GR+ ++L N+ + + A+LMG SK+ Sbjct: 61 IESFTLTLLWSLTVSMFPFGGFIGSLMVGFLVNNLGRKGALLFNNIFSILPAILMGCSKI 120 Query: 116 GKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFG 175 KSFE++I R ++G+ G+++ VPMY+GE++P LRGALG + QL I VGIL+AQ+FG Sbjct: 121 AKSFEIIIASRLLVGICAGISSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQLFG 180 Query: 176 LDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTA 235 L S++ +++ WP+LL + +PA LQ ++LPF PESPR+LLI + E+ A+ L+ LRG Sbjct: 181 LRSVLASEEGWPILLGLTGVPAGLQLLLLPFFPESPRYLLIQKKNESAAEKALQTLRGWK 240 Query: 236 DVTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYST 295 DV +++E+++E +++ +LFR + R ++ +VL QQLSG+NA++YY+ Sbjct: 241 DVDMEMEEIRKEDEAEKAAGFISVWKLFRMQSLRWQLISTIVLMAGQQLSGVNAIYYYAD 300 Query: 296 SIFEKAGVQQP--VYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTI 353 I+ AGV+ Y T G+G VN T+V++FVVE GRR L LIG + I++T+ Sbjct: 301 QIYLSAGVKSNDVQYVTAGTGAVNVFMTMVTVFVVELWGRRNLLLIGFSTCLTACIVLTV 360 Query: 354 ALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWT 413 ALAL + WM Y+SIV + +V VGP PIP + E+F Q RP+A + G +W Sbjct: 361 ALALQNTISWMPYVSIVCVIVYVIGHAVGPSPIPALFITEIFLQSSRPSAYMIGGSVHWL 420 Query: 414 SNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGAS 473 SNFIVG+ F +++ GPY FIIF ++ +L I+ + VPETKGRTF EI F + Sbjct: 421 SNFIVGLIFPFIQVGLGPYSFIIFAIICLLTTIYIFMVVPETKGRTFVEINQIFAKKN-K 479 Query: 474 QSDKTPEE 481 SD PE+ Sbjct: 480 VSDVYPEK 487 >4YB9-D nrPDB Length = 479 Score = 552 bits (1422), Expect = e-157, Method: Composition-based stats. Identities = 205/474 (43%), Positives = 302/474 (63%), Gaps = 8/474 (1%) Query: 1 MEPSSK-----KLTGRLMLAVGGAVLGS-LQFGYNTGVINAPQKVIEEFYNQTWVHRYGE 54 MEP +LT ++LA A GS Q+GYN IN+P + +++FY T+ R GE Sbjct: 1 MEPQDPVKREGRLTPVIVLATLIAAFGSSFQYGYNVAAINSPSEFMKDFYAYTYYDRVGE 60 Query: 55 SILPTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSK 114 + LT LWS++V++F GG +GS VG VN GR+ ++L N+ + V A+LMGFS+ Sbjct: 61 YMNEFYLTLLWSVTVSMFPFGGFLGSLMVGPLVNNLGRKGTLLFNNIFSIVPALLMGFSE 120 Query: 115 LGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVF 174 L KSFEM+I+ R ++G+ GL++ VPMY+GE++P RGALG + QL I +GIL+AQ+F Sbjct: 121 LAKSFEMIIVARVLVGICAGLSSNVVPMYLGELAPKNWRGALGVVPQLFITIGILVAQIF 180 Query: 175 GLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGT 234 GL S++ N++ WP+LL + IPA+LQ + LPF PESPR+LLI + +E AKS L++LRG Sbjct: 181 GLRSLLANEEGWPILLGLTGIPAVLQLLFLPFFPESPRYLLIQKKDEAAAKSALRRLRGW 240 Query: 235 ADVTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYS 294 DV +++E+ EE R +++L+LF+ + R ++ +VL QQLSG+NA++YY+ Sbjct: 241 HDVDAEIEEILEEDRAEKAVGFISVLKLFKMRSLRWQVISIIVLMAGQQLSGVNAIYYYA 300 Query: 295 TSIFEKAGVQQP--VYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMT 352 I+ AGV + Y T G+G VN TV ++FVVE GRR L L+G + ++T Sbjct: 301 DQIYLSAGVNEDDVQYVTAGTGAVNVLITVCAIFVVELMGRRFLLLLGFSVCFTACCVLT 360 Query: 353 IALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNW 412 ALAL + + WM Y+SI + +V +GP PIP +V E+F Q RPAA VAG +W Sbjct: 361 GALALQDVISWMPYVSIACVISYVIGHALGPSPIPALLVTEIFLQSSRPAAYMVAGTVHW 420 Query: 413 TSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASG 466 SNF VG+ F +++ G Y F+IF V+ +L ++ + +PETK +TF EI Sbjct: 421 LSNFTVGLVFPFIQVGLGAYSFVIFAVICLLTTVYIFLIIPETKSKTFIEINRE 474 >6H7D-A nrPDB Length = 521 Score = 440 bits (1132), Expect = e-124, Method: Composition-based stats. Identities = 125/486 (25%), Positives = 230/486 (47%), Gaps = 39/486 (8%) Query: 8 LTGRLMLAVGGAVLGSLQFGYNTGV---INAPQKVIEEFYNQTWV------HRYGESILP 58 +T +++ A +G L FGY+ G+ + + ++ + +F+ Q H Sbjct: 22 VTAFVIMTCIVAAMGGLLFGYDLGISGGVTSMEEFLTKFFPQVESQMKKAKHDTAYCKFD 81 Query: 59 TTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKS 118 + L++ S+ + ++ SF + + GR+ SM + L + A+ F+ + Sbjct: 82 NQMLQLFTSSLYL---AALVASFMASVITRKHGRKVSMFIGGLAFLIGAL---FNAFAVN 135 Query: 119 FEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDS 178 MLI+GR ++GV G P+Y+ E++P +RGAL Q+ I +GIL+A + + Sbjct: 136 VSMLIIGRLLLGVGVGFANQSTPVYLSEMAPAKIRGALNIGFQMAITIGILVANLINYGT 195 Query: 179 IMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVT 238 + W + L + +PA++ I P++P +L R + AK +LKK+RG +V Sbjct: 196 SKMAQHGWRVSLGLAAVPAVVMVIGSFILPDTPNSML-ERGKNEEAKQMLKKIRGADNVD 254 Query: 239 HDLQEMKE--ESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTS 296 H+ Q++ + E+ + + I+E YR ++ + QQ++GIN + +Y+ Sbjct: 255 HEFQDLIDAVEAAKKVENPWKNIME----SKYRPALIFCSAIPFFQQITGINVIMFYAPV 310 Query: 297 IFEKAGV--QQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILM--- 351 +F+ G + + + +G+VN T VS++ V+R GRR L L G M C +L+ Sbjct: 311 LFKTLGFGDDAALMSAVITGVVNMLSTFVSIYAVDRYGRRLLFLEGGIQMFICQLLVGSF 370 Query: 352 ------TIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIA 405 T L L+ + + +VA F GP+ W + +E+ RPA A Sbjct: 371 IGARFGTSGTGTLTPATADWILAFICV--YVAGFAWSWGPLGWLVPSEICPLEIRPAGQA 428 Query: 406 VAGFSNWTSNFIVGMCFQYVEQLCGPY--VFIIFTVLLVLFFIFTYFKVPETKGRTFDEI 463 + N F++G F + LC +F F ++ + +F YF +PETKG +E+ Sbjct: 429 INVSVNMFFTFLIGQFF--LTMLCHMKFGLFYFFASMVAIMTVFIYFLLPETKGVPIEEM 486 Query: 464 ASGFRQ 469 ++Q Sbjct: 487 GRVWKQ 492 >4GC0-A nrPDB Length = 491 Score = 437 bits (1124), Expect = e-123, Method: Composition-based stats. Identities = 136/500 (27%), Positives = 241/500 (48%), Gaps = 47/500 (9%) Query: 4 SSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTT 63 +++ + + A LG L FGY+T VI+ + + + +++ + + Sbjct: 2 NTQYNSSYIFSITLVATLGGLLFGYDTAVISGTVESLNTVFVAP------QNLSESAANS 55 Query: 64 LWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKS----- 118 L VA +G +IG G NRFGRR+S+ + +L F+S V + +LG + Sbjct: 56 LLGFCVASALIGCIIGGALGGYCSNRFGRRDSLKIAAVLFFISGVGSAWPELGFTSINPD 115 Query: 119 ----------FEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGI 168 ++ R I G+ GL + PMY+ E++P +RG L + +Q I+ G Sbjct: 116 NTVPVYLAGYVPEFVIYRIIGGIGVGLASMLSPMYIAELAPAHIRGKLVSFNQFAIIFGQ 175 Query: 169 LIAQVFGL------DSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEEN 222 L+ D+ N D W + + IPALL ++L PESPR+L+ +R ++ Sbjct: 176 LLVYCVNYFIARSGDASWLNTDGWRYMFASECIPALLFLMLLYTVPESPRWLM-SRGKQE 234 Query: 223 RAKSVLKKLRGTADVTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQ 282 +A+ +L+K+ G T +QE+K K L +F I+I V+L + Q Sbjct: 235 QAEGILRKIMGNTLATQAVQEIKHSLDH--GRKTGGRLLMFGVGV----IVIGVMLSIFQ 288 Query: 283 QLSGINAVFYYSTSIFEKAGVQQPV--YATIGSGIVNTAFTVVSLFVVERAGRRTLHLIG 340 Q GIN V YY+ +F+ G + TI G++N FTV+++ V++ GR+ L +IG Sbjct: 289 QFVGINVVLYYAPEVFKTLGASTDIALLQTIIVGVINLTFTVLAIMTVDKFGRKPLQIIG 348 Query: 341 LAGMAGCAILMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPR 400 GMA + ++ A Q P ++++++ +VA F + GP+ W +++E+F R Sbjct: 349 ALGMA--IGMFSLGTAFYTQAP--GIVALLSMLFYVAAFAMSWGPVCWVLLSEIFPNAIR 404 Query: 401 PAAIAVAGFSNWTSNFIVGMCFQYVE-------QLCGPYVFIIFTVLLVLFFIFTYFKVP 453 A+A+A + W +N+ V F ++ + + I+ + VL +F + VP Sbjct: 405 GKALAIAVAAQWLANYFVSWTFPMMDKNSWLVAHFHNGFSYWIYGCMGVLAALFMWKFVP 464 Query: 454 ETKGRTFDEIASGFRQGGAS 473 ETKG+T +E+ + + Sbjct: 465 ETKGKTLEELEALWEPETKK 484 >4LDS-A nrPDB Length = 446 Score = 392 bits (1006), Expect = e-109, Method: Composition-based stats. Identities = 127/414 (30%), Positives = 233/414 (56%), Gaps = 15/414 (3%) Query: 66 SLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILG 125 + V+ +G ++G+ S G ++ GRR ++++ ++ + A+++ S + +LI+G Sbjct: 45 GIVVSSMLIGAIVGAGSSGPLADKLGRRRLVMLIAIVFIIGALILAAST---NLALLIIG 101 Query: 126 RFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDL 185 R IIG+ G + VP+Y+ E++PT RG+LG+L+QL I +GIL A + + + Sbjct: 102 RLIIGLAVGGSMSTVPVYLSEMAPTEYRGSLGSLNQLMITIGILAAYLVNY--AFADIEG 159 Query: 186 WPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMK 245 W +L + +P+++ + + F PESPR+LL NRN E A+ V+K +++ +L+EMK Sbjct: 160 WRWMLGLAVVPSVILLVGIYFMPESPRWLLENRN-EEAARQVMKITYDDSEIDKELKEMK 218 Query: 246 EESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQ 305 E + E T++ +SP + +++ + + QQ GINAV +YS+SIF KAG+ + Sbjct: 219 E--INAISESTWTVI---KSPWLGRILIVGCIFAIFQQFIGINAVIFYSSSIFAKAGLGE 273 Query: 306 P--VYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQLPW 363 + ++G G +N T+V++FVV++ R+ L + G GM ++M I + + + Sbjct: 274 AASILGSVGIGTINVLVTIVAIFVVDKIDRKKLLVGGNIGMIASLLIMAILIWTI-GIAS 332 Query: 364 MSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQ 423 +++ IV + F+ FF + GP+ W ++ ELF R AA ++ IV + F Sbjct: 333 SAWIIIVCLSLFIVFFGISWGPVLWVMLPELFPMRARGAATGISALVLNIGTLIVSLFFP 392 Query: 424 YV-EQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSD 476 + + L +VF+IF + VL IF +PET+GR+ +EI R+ ++++ Sbjct: 393 ILSDALSTEWVFLIFAFIGVLAMIFVIKFLPETRGRSLEEIEYELRERTGARTE 446 >4J05-A nrPDB Length = 530 Score = 90.1 bits (222), Expect = 2e-18, Method: Composition-based stats. Identities = 90/507 (17%), Positives = 171/507 (33%), Gaps = 72/507 (14%) Query: 16 VGGAVLGSLQFGYNTGVINAPQKVIEE-FYNQTWVHRYGESILPTTLTTLWSLSVAIFSV 74 V A +G Y+ +IN ++ + ++ +T + + ++ + Sbjct: 37 VLLAGVGFFLDAYDLFIINQVAPMLAQVYFPKTGLPAQRQDLMKAAAN-----------I 85 Query: 75 GGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVL-MGFSKL---GKSFEMLILGRFIIG 130 G ++G G+ + FGR+ +L V+ + M + + + R +G Sbjct: 86 GCVVGQVMFGVLGDSFGRKFVYGKELILIIVATIFQMSAPSHWDGNRVLTWITICRVFLG 145 Query: 131 VYCGLTTGFVPMYVGEVSPTALRGAL--------GTLHQLGIVVGILIAQVFGLDSIMGN 182 + G V + + RG L G +G +V I+ F G+ Sbjct: 146 IGIGGDYPMSATVVSDRANIHRRGTLLCFIFANQGWGSFVGSLVTIVTISGFKHRLKSGH 205 Query: 183 KD----LWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVT 238 W +L+ + IPA PES +F L + + S + + D T Sbjct: 206 THDVDKAWRILIGLSLIPAFGTLYQRLTLPESRKFELT---RDAASSSTVAIDKKDHDAT 262 Query: 239 HDLQEM---------------KEESRQMMREKKVTILELFR---SPAYRQPILIAVVLQL 280 H++++ ++ R + K + F S L+ +L Sbjct: 263 HEVKDAPESEKSSPKVTPADAIDDDRHGVIASKKAHWQEFVAYFSTWNHFRNLLGSMLGW 322 Query: 281 SQ---QLSGIN---AVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVV--------SLF 326 GIN +V K G + +G N T + +LF Sbjct: 323 FLVDIAFYGINLNQSVVLAQIGFAGKTGDVYDKLFQLATG--NIIVTALGFLPGYYFTLF 380 Query: 327 VVERAGRRTLHLIGLAGMAGCAILMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPI 386 +++ GR+ L +G + + I ++ + L+ FF G Sbjct: 381 LIDIVGRKKLQFMGFI---MSGLFLAILAGEIDHIGKGPLLA--CFTFMQFFFNFGANTT 435 Query: 387 PWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCG-PYVFIIFTVLLVLFF 445 + + AELF R +A ++ + + + F ++ G V IF +L F Sbjct: 436 TFIVAAELFPTRIRASAHGISAAAGKCGAILSSLVFNQLKAKIGTSAVLWIFFSTCILGF 495 Query: 446 IFTYFKVPETKGRTFDEIASGFRQGGA 472 I T+ + ET G DE R+ Sbjct: 496 ISTF-LIDETMGVDPDEKDLEERRARG 521 >4W6V-A nrPDB Length = 519 Score = 37.3 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 31/153 (20%), Positives = 61/153 (39%), Gaps = 8/153 (5%) Query: 66 SLSVAIFSVGGMIGSFSVGLFVNR-FGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLIL 124 S V IF+ + + GL + G++ ++ ++L + + + S + ++ + Sbjct: 62 SAIVGIFAGSMYLAALPGGLLADNWLGQQRAVWYGSILIALGHLSIALSAFFGN-DLFFI 120 Query: 125 GRFIIGVYCGLTTGFVPMYVGEV-SPTALRGALG-TLHQLGIVVGILIAQVFGLDSIMGN 182 G I + GL + + VG + P R G +L +GI +G IA + L + Sbjct: 121 GLVFIVLGTGLFKTCISVMVGTLYKPGDARRDGGFSLFYMGINMGSFIAPL--LSGWLLR 178 Query: 183 KDLWPLLLSIIFIPALLQCIVL--PFCPESPRF 213 W I I L+ ++ P R+ Sbjct: 179 THGWHWGFGIGGIGMLVALLIFRGFAIPAMKRY 211 >6E9N-A nrPDB Length = 460 Score = 35.8 bits (81), Expect = 0.047, Method: Composition-based stats. Identities = 63/379 (16%), Positives = 120/379 (31%), Gaps = 36/379 (9%) Query: 83 VGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPM 142 G F++R G R + + V+ + GF+ S LI R I G++ Sbjct: 86 GGWFLDRVGSRVTYFIAIFGWSVATLFQGFATGLMS---LIGLRAITGIFEAPAFPTNNR 142 Query: 143 YVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCI 202 V P R + + G VG +A + L + W + + ++ + Sbjct: 143 MVTSWFPEHERASAVGFYTSGQFVG--LAFLTPLLIWIQEMLSWHWVFIVTGGIGIIWSL 200 Query: 203 VLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMKEESRQMMREKKVTILEL 262 + + PR + + ++ G D ++ KE + + + + Sbjct: 201 IWFKVYQPPR---LTKGISKAELDYIRDGGGLVDGDAPVK--KEARQPLTAKDWKLVFHR 255 Query: 263 FRSPAYRQPILIAVVLQLS--------QQLSGINAVFYYSTSIFEKAGVQQPV-YATIGS 313 Y +A L Q GI A+ KAG V + Sbjct: 256 KLIGVYLGQFAVASTLWFFLTWFPNYLTQEKGITAL---------KAGFMTTVPFLAAFV 306 Query: 314 GIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQLPWMSYLSIVAIF 373 G+ ++S +V + R+ L L+ + + I+ + Sbjct: 307 GV------LLSGWVADLLVRKGFSLGFARKTPIICGLLISTCIMGANYTNDPMM-IMCLM 359 Query: 374 GFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYV 433 +AFF G I W +V+ L V F+ V + Y+ Q G Sbjct: 360 A-LAFFGNGFASITWSLVSSLAPMRLIGLTGGVFNFAGGLGGITVPLVVGYLAQGYGFAP 418 Query: 434 FIIFTVLLVLFFIFTYFKV 452 +++ + L +Y + Sbjct: 419 ALVYISAVALIGALSYILL 437 >6EUQ-A nrPDB Length = 419 Score = 33.8 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 62/359 (17%), Positives = 128/359 (35%), Gaps = 56/359 (15%) Query: 68 SVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRF 127 S+ + GGM + +G +R GRR ML + V+ + + L ++ E L RF Sbjct: 57 SMTAYLAGGMFLQWLLGPLSDRIGRRPVMLAGVVWFIVTCLAIL---LAQNIEQFTLLRF 113 Query: 128 IIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGI----LIAQVFG--LDSIMG 181 + G+ ++G V A+R + + I + LIA + G + + Sbjct: 114 LQGISL--------CFIGAVGYAAIRESFEEAVCIKITALMANVALIAPLLGPLVGAAWI 165 Query: 182 NKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDL 241 + W + + A + L R A + +KL ++ D Sbjct: 166 HVLPWEGMFVLFAALAAISFFGL------------QRAMPETATRIGEKL-SLKELGRDY 212 Query: 242 QEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKA 301 + + + R + + + L P +++ +QLS +E Sbjct: 213 KLVLKNGRFVAGALALGFVSL---PLLAWIAQSPIIIITGEQLSS-----------YEYG 258 Query: 302 GVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQL 361 +Q P++ + +G + +++ R R + + G M G +L+ A ++ Sbjct: 259 LLQVPIFGALIAGNL-----LLARLTSRRTVRSLIIMGGWPIMIG--LLVAAAATVISSH 311 Query: 362 PWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM 420 ++ + ++I+ F +G + E S + A G F VG+ Sbjct: 312 AYLWMTAGLSIY----AFGIGLANAGLVRLTEFASDMSKGTVSAAMGMLQMLI-FTVGI 365 >3WDO-A nrPDB Length = 453 Score = 30.0 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 27/157 (17%), Positives = 59/157 (37%), Gaps = 14/157 (8%) Query: 302 GVQQPVYATIG--SGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLE 359 G + + G+ F + + +R GR+ L + GLA A +++ ++ ++ Sbjct: 42 GASEALIGIAIGIYGLTQAVFQIPFGLLSDRIGRKPLIVGGLAVFAAGSVIAALSDSIWG 101 Query: 360 QLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVG 419 + + AI V ++++L + R A+A G S + I Sbjct: 102 IILGRALQGSGAIAAAVMA-----------LLSDLTREQNRTKAMAFIGVSFGITFAIAM 150 Query: 420 MCFQYVEQLCGPY-VFIIFTVLLVLFFIFTYFKVPET 455 + + G + +F + +L T + VP + Sbjct: 151 VLGPIITHKLGLHALFWMIAILATTGIALTIWVVPNS 187 >1PW4-A nrPDB Length = 451 Score = 28.8 bits (63), Expect = 4.9, Method: Composition-based stats. Identities = 18/144 (12%), Positives = 52/144 (36%), Gaps = 5/144 (3%) Query: 66 SLSVAIFSVGGMIGSFSVGLFVNRF--GRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLI 123 S + ++ G+ G+ G ++ G R + + + A ++ + + + + Sbjct: 291 SWAYFLYEYAGIPGTLLCGWMSDKVFRGNRGATGVFFMTLVTIATIVYWMNPAGNPTVDM 350 Query: 124 LGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSI---M 180 + +IG + ++ E++P G L +G +A + Sbjct: 351 ICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFGYLGGSVAASAIVGYTVDFF 410 Query: 181 GNKDLWPLLLSIIFIPALLQCIVL 204 G + +++ + +L +V+ Sbjct: 411 GWDGGFMVMIGGSILAVILLIVVM 434 >5O7H-B nrPDB Length = 167 Score = 28.4 bits (62), Expect = 8.0, Method: Composition-based stats. Identities = 20/111 (18%), Positives = 46/111 (41%), Gaps = 7/111 (6%) Query: 158 TLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLIN 217 + Q+ + +G L ++ G S++ + L + Q + P+ ++ +++ Sbjct: 29 SFPQMKLSLGQLF-RIHGDASLLHDLQGLDWLGPLAGY---CQVTAVSAVPDHVQYRIVS 84 Query: 218 RNEENRAKSVLKKLRGTADVTHDLQEMKEESRQMMREKKVT-ILELFRSPA 267 N +K+ LK+L + D + K +M+ + L+LF S Sbjct: 85 VKRSNLSKAKLKRLIARGSIDKDGE--KRYKVKMLGQGFDNPYLDLFSSST 133 >3O8N-A nrPDB Length = 762 Score = 28.1 bits (61), Expect = 8.9, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 43/86 (50%), Gaps = 3/86 (3%) Query: 187 PLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMK- 245 +L S + + A++ +L P++P ++ + +++ ++ T DVT + E + Sbjct: 310 RILGSRMGVEAVM--ALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKRF 367 Query: 246 EESRQMMREKKVTILELFRSPAYRQP 271 +E+ ++ + E+++ A+ +P Sbjct: 368 DEAMKLRGRSFMNNWEVYKLLAHIRP 393 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.322 0.139 0.361 Lambda K H 0.267 0.0424 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,416,618 Number of Sequences: 36641 Number of extensions: 657439 Number of successful extensions: 2385 Number of sequences better than 10.0: 41 Number of HSP's better than 10.0 without gapping: 22 Number of HSP's successfully gapped in prelim test: 34 Number of HSP's that attempted gapping in prelim test: 2281 Number of HSP's gapped (non-prelim): 67 length of query: 492 length of database: 10,336,785 effective HSP length: 101 effective length of query: 391 effective length of database: 6,636,044 effective search space: 2594693204 effective search space used: 2594693204 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.4 bits) S2: 61 (28.1 bits)