BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P11157 (390 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1H0O-A nrPDB 811 0.0 2UW2-A nrPDB 657 0.0 3OLJ-A nrPDB 581 e-166 3HF1-A nrPDB 575 e-164 4DJN-A nrPDB 531 e-151 1SMQ-A nrPDB 474 e-134 2P1I-A nrPDB 395 e-110 2O1Z-A nrPDB 351 3e-97 1SMS-A nrPDB 330 7e-91 4M1I-A nrPDB 132 3e-31 2RCC-A nrPDB 72 5e-13 1PIY-A nrPDB 68 7e-12 4DR0-A nrPDB 61 1e-09 4BMQ-A nrPDB 57 1e-08 4N83-A nrPDB 57 2e-08 6QRZ-A nrPDB 55 5e-08 2BQ1-I nrPDB 51 9e-07 3MJO-A nrPDB 49 3e-06 3DHZ-A nrPDB 49 5e-06 6EBP-A nrPDB 46 3e-05 4AC8-A nrPDB 44 1e-04 6GP2-A nrPDB 42 4e-04 3N37-A nrPDB 40 0.002 6CWO-A nrPDB 36 0.026 6CWP-A nrPDB 36 0.030 5OOM-5 nrPDB 34 0.11 5OMK-A nrPDB 33 0.17 5OLK-A nrPDB 33 0.27 3QD9-A nrPDB 32 0.44 3V4P-B nrPDB 31 1.1 4FL0-A nrPDB 29 4.0 6CVC-A nrPDB 29 4.3 >1H0O-A nrPDB Length = 390 Score = 811 bits (2095), Expect = 0.0, Method: Compositional matrix adjust. Identities = 390/390 (100%), Positives = 390/390 (100%) Query: 1 MLSVRTPLATIADQQQLQLSPLKRLTLADKENTPPTLSSTRVLASKAARRIFQDSAELES 60 MLSVRTPLATIADQQQLQLSPLKRLTLADKENTPPTLSSTRVLASKAARRIFQDSAELES Sbjct: 1 MLSVRTPLATIADQQQLQLSPLKRLTLADKENTPPTLSSTRVLASKAARRIFQDSAELES 60 Query: 61 KAPTNPSVEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEAL 120 KAPTNPSVEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEAL Sbjct: 61 KAPTNPSVEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEAL 120 Query: 121 KPDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLL 180 KPDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLL Sbjct: 121 KPDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLL 180 Query: 181 IDTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGS 240 IDTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGS Sbjct: 181 IDTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGS 240 Query: 241 FASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRI 300 FASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRI Sbjct: 241 FASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRI 300 Query: 301 EQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISLEGKT 360 EQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISLEGKT Sbjct: 301 EQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISLEGKT 360 Query: 361 NFFEKRVGEYQRMGVMSNSTENSFTLDADF 390 NFFEKRVGEYQRMGVMSNSTENSFTLDADF Sbjct: 361 NFFEKRVGEYQRMGVMSNSTENSFTLDADF 390 >2UW2-A nrPDB Length = 332 Score = 657 bits (1696), Expect = 0.0, Method: Compositional matrix adjust. Identities = 310/325 (95%), Positives = 321/325 (98%) Query: 66 PSVEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEALKPDER 125 P VEDEPLLRENPRRFV+FPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWE+LKP+ER Sbjct: 8 PGVEDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEER 67 Query: 126 HFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYI 185 +FISHVLAFFAASDGIVNENLVERFSQEVQ+TEARCFYGFQIAMENIHSEMYSLLIDTYI Sbjct: 68 YFISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYI 127 Query: 186 KDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIF 245 KDPKERE+LFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIF Sbjct: 128 KDPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIF 187 Query: 246 WLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRIEQEFL 305 WLKKRG MPGLTFSNELISRDEGLHCDFACLMFKHLVHKP+E+RVREII NAVRIEQEFL Sbjct: 188 WLKKRGPMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFL 247 Query: 306 TEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISLEGKTNFFEK 365 TEALPVKLIGMNCTLMKQYIEFVADRLMLELGF+K+FRVENPFDFMENISLEGKTNFFEK Sbjct: 248 TEALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGKTNFFEK 307 Query: 366 RVGEYQRMGVMSNSTENSFTLDADF 390 RVGEYQRMGVMS+ TENSFTLDADF Sbjct: 308 RVGEYQRMGVMSSPTENSFTLDADF 332 >3OLJ-A nrPDB Length = 286 Score = 581 bits (1497), Expect = e-166, Method: Compositional matrix adjust. Identities = 273/285 (95%), Positives = 283/285 (99%) Query: 67 SVEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEALKPDERH 126 VEDEPLLRENPRRFV+FPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWE+LKP+ER+ Sbjct: 2 GVEDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERY 61 Query: 127 FISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIK 186 FISHVLAFFAASDGIVNENLVERFSQEVQ+TEARCFYGFQIAMENIHSEMYSLLIDTYIK Sbjct: 62 FISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIK 121 Query: 187 DPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFW 246 DPKERE+LFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFW Sbjct: 122 DPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFW 181 Query: 247 LKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRIEQEFLT 306 LKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKP+E+RVREII NAVRIEQEFLT Sbjct: 182 LKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLT 241 Query: 307 EALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFM 351 EALPVKLIGMNCTLMKQYIEFVADRLMLELGF+K+FRVENPFDFM Sbjct: 242 EALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFM 286 >3HF1-A nrPDB Length = 351 Score = 575 bits (1481), Expect = e-164, Method: Compositional matrix adjust. Identities = 268/334 (80%), Positives = 307/334 (91%), Gaps = 3/334 (0%) Query: 60 SKAPTNPS---VEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQH 116 S + TN S +EPLLR++ RRFV+FPI+Y DIW+MYK+A+ASFWTAEEVDLSKD+ H Sbjct: 18 SSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPH 77 Query: 117 WEALKPDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEM 176 W LK DE++FISH+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +EN+HSEM Sbjct: 78 WNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEM 137 Query: 177 YSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIF 236 YSLLIDTYI+DPK+RE+LFNAIETMP VKKKADWALRWI D+++T+GERVVAFAAVEG+F Sbjct: 138 YSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVF 197 Query: 237 FSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITN 296 FSGSFA+IFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMF++LV+KP+E+RVREII + Sbjct: 198 FSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVD 257 Query: 297 AVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISL 356 AV+IEQEFLTEALPV LIGMNC LMKQYIEFVADRL++ELGF+K+F+ ENPFDFMENISL Sbjct: 258 AVKIEQEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISL 317 Query: 357 EGKTNFFEKRVGEYQRMGVMSNSTENSFTLDADF 390 EGKTNFFEKRV EYQR VM+ +T+N FTLDADF Sbjct: 318 EGKTNFFEKRVSEYQRFAVMAETTDNVFTLDADF 351 >4DJN-A nrPDB Length = 311 Score = 531 bits (1367), Expect = e-151, Method: Compositional matrix adjust. Identities = 247/305 (80%), Positives = 283/305 (92%), Gaps = 3/305 (0%) Query: 60 SKAPTNPS---VEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQH 116 S + TN S +EPLLR++ RRFV+FPI+Y DIW+MYK+A+ASFWTAEEVDLSKD+ H Sbjct: 7 SSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPH 66 Query: 117 WEALKPDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEM 176 W LK DE++FISH+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +EN+HSEM Sbjct: 67 WNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEM 126 Query: 177 YSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIF 236 YSLLIDTYI+DPK+RE+LFNAIETMP VKKKADWALRWI D+++T+GERVVAFAAVEG+F Sbjct: 127 YSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVF 186 Query: 237 FSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITN 296 FSGSFA+IFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMF++LV+KP+E+RVREII + Sbjct: 187 FSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVD 246 Query: 297 AVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISL 356 AV+IEQEFLTEALPV LIGMNC LMKQYIEFVADRL++ELGF+K+F+ ENPFDFMENISL Sbjct: 247 AVKIEQEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISL 306 Query: 357 EGKTN 361 EGKTN Sbjct: 307 EGKTN 311 >1SMQ-A nrPDB Length = 399 Score = 474 bits (1221), Expect = e-134, Method: Compositional matrix adjust. Identities = 237/392 (60%), Positives = 289/392 (73%), Gaps = 21/392 (5%) Query: 3 SVRTPLATIADQQQLQLSPLKRLTLADKENTPPTLSSTRVLASKAARRIFQDSAELESKA 62 ++ L T+ ++ +++ LK D EN L S +V K E+E Sbjct: 25 NLNKELETLREENRVKSDMLKEKLSKDAENHKAYLKSHQVHRHKLK--------EME--- 73 Query: 63 PTNPSVEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEA-LK 121 ++EPLL E+ R V+FPI+YH+IWQ YK+AEASFWTAEE+DLSKDI W + Sbjct: 74 ------KEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMN 127 Query: 122 PDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLI 181 +ER FIS VLAFFAASDGIVNENLVE FS EVQ+ EA+ FYGFQI +ENIHSE YSLLI Sbjct: 128 ENERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLI 187 Query: 182 DTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSF 241 DTYIKDPKE E+LFNAI T+P + +KA+WALRWI D +A +GER+VAFA++EG+FFSGSF Sbjct: 188 DTYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSF 247 Query: 242 ASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRIE 301 ASIFWLKKRG+MPGLTFSNELI RDEGLH DFACL+F HL +KP V +I+T AV IE Sbjct: 248 ASIFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIE 307 Query: 302 QEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISLEGKTN 361 Q + +ALPV L+GMN LM QY+EFVADRL++ G K ++VENPFDFMENISL GKTN Sbjct: 308 QRYFLDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENISLAGKTN 367 Query: 362 FFEKRVGEYQRMGVMSNSTE---NSFTLDADF 390 FFEKRV +YQ+ GVMS ST+ +FT + DF Sbjct: 368 FFEKRVSDYQKAGVMSKSTKQEAGAFTFNEDF 399 >2P1I-A nrPDB Length = 349 Score = 395 bits (1016), Expect = e-110, Method: Compositional matrix adjust. Identities = 190/321 (59%), Positives = 240/321 (74%), Gaps = 1/321 (0%) Query: 70 DEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFIS 129 +E +L + RF + PI Y ++W YKKAEASFWTAEE+DLS D++ +E L +E+HFI Sbjct: 30 NEKILNKESNRFTLHPIMYPEVWNFYKKAEASFWTAEEIDLSSDLKDFEKLNVNEKHFIK 89 Query: 130 HVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPK 189 HVLAFFAASDGIV ENL +F +EV++ EA+ FY FQIA+ENIHSE YSLLID YIKD K Sbjct: 90 HVLAFFAASDGIVLENLASKFLREVEIIEAKKFYSFQIAVENIHSETYSLLIDNYIKDEK 149 Query: 190 EREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKK 249 ER LF+AIE +P +K KA WA +WI D ++ ER+VA A VEGI FSGSF +IFW KK Sbjct: 150 ERLNLFHAIENIPAIKNKALWAAKWINDTN-SFAERIVANACVEGILFSGSFCAIFWFKK 208 Query: 250 RGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRIEQEFLTEAL 309 + + GLTFSNELISRDEGLH DF CL++ L +K E V+ I+ AV +E+ F+ E+L Sbjct: 209 QNKLHGLTFSNELISRDEGLHTDFNCLIYSLLENKLPENVVQNIVKEAVEVERSFICESL 268 Query: 310 PVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISLEGKTNFFEKRVGE 369 P LIGMN LM QYIEFVADRL+ LG +K+F +NPF++M+ ISL+GKTNFFEKRV + Sbjct: 269 PCDLIGMNSRLMSQYIEFVADRLLECLGCSKVFHSKNPFNWMDLISLQGKTNFFEKRVAD 328 Query: 370 YQRMGVMSNSTENSFTLDADF 390 YQ+ GVM+ E F+L+ DF Sbjct: 329 YQKSGVMAQRKEQVFSLNTDF 349 >2O1Z-A nrPDB Length = 311 Score = 351 bits (900), Expect = 3e-97, Method: Compositional matrix adjust. Identities = 170/283 (60%), Positives = 213/283 (75%), Gaps = 1/283 (0%) Query: 70 DEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFIS 129 +E +L + RF ++PI Y D+W YKKAEASFWTAEE+DLS D++ +E L +E+HFI Sbjct: 29 NEKILSKETDRFTLYPILYPDVWDFYKKAEASFWTAEEIDLSSDLKDFEKLNDNEKHFIK 88 Query: 130 HVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPK 189 HVLAFFAASDGIV ENL +F ++V++TEA+ FY FQIA+ENIHSE YSLLID YIKD K Sbjct: 89 HVLAFFAASDGIVLENLASKFLRQVKITEAKKFYAFQIAVENIHSETYSLLIDNYIKDEK 148 Query: 190 EREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKK 249 ER LF+AIE +P VK KA WA +WI D ++ ER+VA A VEGI FSGSF +IFW KK Sbjct: 149 ERMNLFHAIENIPAVKNKALWAAKWINDTN-SFAERIVANACVEGILFSGSFCAIFWFKK 207 Query: 250 RGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRIEQEFLTEAL 309 + + GLTFSNELISRDEGLH DF CL++ L +K E+ V+ I+ AV +E+ F+ E+L Sbjct: 208 QNKLHGLTFSNELISRDEGLHTDFNCLIYSLLENKLPEEVVQNIVKEAVEVERSFICESL 267 Query: 310 PVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFME 352 P LIGMN LM QYIEFVADRL+ LG KIF +NPF++M+ Sbjct: 268 PCDLIGMNSRLMSQYIEFVADRLLECLGSPKIFHAKNPFNWMD 310 >1SMS-A nrPDB Length = 345 Score = 330 bits (846), Expect = 7e-91, Method: Compositional matrix adjust. Identities = 159/324 (49%), Positives = 222/324 (68%), Gaps = 3/324 (0%) Query: 69 EDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFI 128 +DE LL EN RRFV+FPI+YH+IW YKK EASFWTAEE++L+KD + ++ L D++ +I Sbjct: 23 KDEILLMENSRRFVMFPIKYHEIWAAYKKVEASFWTAEEIELAKDTEDFQKLTDDQKTYI 82 Query: 129 SHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDP 188 ++LA +SD +VN+ L+E FS ++Q E + FYGFQI MENI+SE+YS+++D + KDP Sbjct: 83 GNLLALSISSDNLVNKYLIENFSAQLQNPEGKSFYGFQIMMENIYSEVYSMMVDAFFKDP 142 Query: 189 KEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLK 248 K LF I +P VK KA + RWI + ++ Y ER+VAFAA EGIF +G++AS+FWL Sbjct: 143 KNIP-LFKEIANLPEVKHKAAFIERWISNDDSLYAERLVAFAAKEGIFQAGNYASMFWLT 201 Query: 249 KRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRIEQEFLTEA 308 + +MPGL +N I RD G + DF+CL+F HL KP + + +IIT AV IE+E+ + + Sbjct: 202 DKKIMPGLAMANRNICRDRGAYTDFSCLLFAHLRTKPNPKIIEKIITEAVEIEKEYYSNS 261 Query: 309 LPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISLEGKTNFFEKRVG 368 LPV+ GM+ + YIEFVAD L+ G K + NPF+FME+++ GKT FFEK+V Sbjct: 262 LPVEKFGMDLKSIHTYIEFVADGLLQGFGNEKYYNAVNPFEFMEDVATAGKTTFFEKKVS 321 Query: 369 EYQRMGVMSNSTENS--FTLDADF 390 +YQ+ MS S S D DF Sbjct: 322 DYQKASDMSKSATPSKEINFDDDF 345 >4M1I-A nrPDB Length = 366 Score = 132 bits (332), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 90/318 (28%), Positives = 151/318 (47%), Gaps = 26/318 (8%) Query: 83 VFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEA--LKPDERHFISHVLAFFAASDG 140 + PI+Y W+ Y A+ W E+ + KDI+ W++ L DER I L FF+ ++ Sbjct: 51 LVPIKYKWAWEHYLNGCANNWLPTEIPMGKDIELWKSDRLSEDERRVILLNLGFFSTAES 110 Query: 141 IVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIET 200 +V N+V + V EAR + Q E +H+ + + ++ D KE +FNA Sbjct: 111 LVGNNIVLAIFKHVTNPEARQYLLRQAFEEAVHTHTFLYICESLGLDEKE---IFNAYNE 167 Query: 201 MPCVKKKADWALRWIGD-------KEATYGER------VVAFAAVEGIFFSGSFASIFWL 247 +K K D+ + G ++ G + V + +EGIFF F I Sbjct: 168 RAAIKAKDDFQMEITGKVLDPNFRTDSVEGLQEFVKNLVGYYIIMEGIFFYSGFVMILSF 227 Query: 248 KKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAE-------QRVREIITNAVRI 300 ++ M G+ + I RDE +H +F + + + E Q + E+I AV + Sbjct: 228 HRQNKMIGIGEQYQYILRDETIHLNFGIDLINGIKEENPEIWTPELQQEIVELIKRAVDL 287 Query: 301 EQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFM-ENISLEGK 359 E E+ + LP ++G+ ++ Y++ +ADR + +G I+ +NPF +M E I L + Sbjct: 288 EIEYAQDCLPRGILGLRASMFIDYVQHIADRRLERIGLKPIYHTKNPFPWMSETIDLNKE 347 Query: 360 TNFFEKRVGEYQRMGVMS 377 NFFE RV EYQ ++ Sbjct: 348 KNFFETRVIEYQHAASLT 365 >2RCC-A nrPDB Length = 346 Score = 71.6 bits (174), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 68/310 (21%), Positives = 144/310 (46%), Gaps = 25/310 (8%) Query: 92 WQMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFS 151 + +YK A+FWT E+++S D + + L E+ ++ A D V + R + Sbjct: 42 YPLYKNMLANFWTPFEINMSHDAKQFPTLTETEQEAFKKIIGLLAFLDS-VQTDYSMRAA 100 Query: 152 QEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWA 211 + + + E +H++ YS ++ + + + E +F + +K++ ++ Sbjct: 101 EYLTDSSLAALMSVLSFQEVVHNQSYSYVLSSLVPKATQDE-IFEYWKHDDVLKERNEFI 159 Query: 212 L----RWIGD-KEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRD 266 + +++ + T+ E +V +EG+ F FA + L + M + I+RD Sbjct: 160 IDGYEKFVDNPTPKTFLESIVYDVILEGLNFYSGFAFFYNLARNQKMVSTSTMINYINRD 219 Query: 267 EGLHCDFACLMFKHLVHKPAEQR-------VREIITNAVRIEQEFLTEALPVKLIGMNCT 319 E LH +FK L+ + E V+ + A +E+++ + K+ G+N Sbjct: 220 EQLHVYLFTNIFKELLVEFPELNTEETKTFVKTTLMKAADLEKDWFRYIIGDKIPGINPE 279 Query: 320 LMKQYIEFVADRLMLELGFNKIFR--VENPFDFM---ENISLEGKTNFFEKRVGEYQRMG 374 M+ YI F+A++ ++LG K + NP ++ E+++ GK++FFE++ +Y ++ Sbjct: 280 DMETYISFIANKRAVQLGMEKPYPEIKHNPMKWIRAYEDVN-SGKSDFFEQKSRQYAKV- 337 Query: 375 VMSNSTENSF 384 S +N F Sbjct: 338 ----SADNGF 343 >1PIY-A nrPDB Length = 375 Score = 67.8 bits (164), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 75/326 (23%), Positives = 131/326 (40%), Gaps = 50/326 (15%) Query: 71 EPLLRENPRRFVVFPIEYHDIWQ-MYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFIS 129 EP+ P + + +DI++ + +K + FW EEVD+S+D ++AL E+H Sbjct: 15 EPMFFGQPVNVARYDQQKYDIFEKLIEKQLSFFWRPEEVDVSRDRIDYQALPEHEKHIFI 74 Query: 130 HVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPK 189 L + D I + + + E + E IHS Y+ +I + DP Sbjct: 75 SNLKYQTLLDSIQGRSPNVALLPLISIPELETWVETWAFSETIHSRSYTHIIRNIVNDPS 134 Query: 190 EREYLFNAIETMPCVKKKAD---------------WALRWIGDKEATYGERVVAFA---- 230 +F+ I T ++K+A+ W L +G+ T + V + Sbjct: 135 ---VVFDDIVTNEQIQKRAEGISSYYDELIEMTSYWHL--LGEGTHTVNGKTVTVSLREL 189 Query: 231 ------------AVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMF 278 A+E I F SFA F +R LM G LI+RDE LH M Sbjct: 190 KKKLYLCLMSVNALEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEALHLTGTQHML 249 Query: 279 KHL-----------VHKPAEQRVREIITNAVRIEQEFLTEAL-PVKLIGMNCTLMKQYIE 326 L + + +Q ++ A + E+++ +IG+N ++ QY+E Sbjct: 250 NLLRSGADDPEMAEIAEECKQECYDLFVQAAQQEKDWADYLFRDGSMIGLNKDILCQYVE 309 Query: 327 FVADRLMLELGFNKIFRV-ENPFDFM 351 ++ + M +G + F NP ++ Sbjct: 310 YITNIRMQAVGLDLPFNTRSNPIPWI 335 >4DR0-A nrPDB Length = 350 Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 70/301 (23%), Positives = 136/301 (45%), Gaps = 19/301 (6%) Query: 90 DIWQM-YKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVE 148 D QM Y + FW EE+ L+ D+ W+ L +E+ VLA D + Sbjct: 37 DFTQMFYNQNVKQFWLPEEIALNGDLLTWKYLGKNEQDTYMKVLAGLTLLDTEQGNTGMP 96 Query: 149 RFSQEVQVTEARCFYGFQIAMEN-IHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKK 207 ++ V + + F MEN +H++ YS + T E +F ++ ++KK Sbjct: 97 IVAEHVDGHQRKAVLNFMAMMENAVHAKSYSNIFMTLAPTETINE-VFEWVKQNKYLQKK 155 Query: 208 ADWALRWI----GDKEATYGERVVAFAAVEG-IFFSGSFASIFWLKKRGLMPGLTFSNEL 262 A + D E + + +VA +E +F+SG + +++ + LM N L Sbjct: 156 AQMIVGLYKAIQKDDEISLFKAMVASVYLESFLFYSGFYYPLYFYGQGKLMQSGEIIN-L 214 Query: 263 ISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRIEQEFLTEALP-----VKLIGMN 317 I RDE +H + L+ + + +K E++ E+ A+ + + L +G++ Sbjct: 215 ILRDEAIHGVYVGLLAQEIYNKQTEEKKAELREFAIDLLNQLYENELEYTEDLYDQVGLS 274 Query: 318 CTLMKQYIEFVADRLMLELGFNKIFRVE--NPFDFMENISLEGKT-NFFEKRVGEYQRMG 374 + K++I + A++ ++ LGF+ F E NP + ++ + K+ +FF + Y++ Sbjct: 275 HDV-KKFIRYNANKALMNLGFDPYFEEEDINPI-VLNGLNTKTKSHDFFSMKGNGYKKAT 332 Query: 375 V 375 V Sbjct: 333 V 333 >4BMQ-A nrPDB Length = 322 Score = 57.4 bits (137), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 64/271 (23%), Positives = 117/271 (43%), Gaps = 25/271 (9%) Query: 95 YKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQEV 154 +K+ A FWT EE+ +S D W L +E+ VL D + + Sbjct: 18 WKQNIAQFWTEEEIAVSSDKNTWVQLSKEEQIAYKRVLGGLTLLDTKQGGEGMPLVLVHL 77 Query: 155 QVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWA--- 211 + +A+ F AME +H++ YS + T + +E + +F+ ++ P ++KKA Sbjct: 78 ENLQAKSVLAFMGAMEEVHAKSYSHIFTT-LATEEEIDDIFDWVDNHPLLEKKAGIITSY 136 Query: 212 LRWIGDKEATYGERVVAFAA---VEGIFFSGSFASIFWLKKRGLMPGLTFSNELIS---R 265 R + E T E +A A +E F F +L +G LT S E+I+ R Sbjct: 137 YRRLLKPEVTKKELYMAMVASVFLESYLFYSGFFYPLYLAGQG---KLTASGEIINLIIR 193 Query: 266 DEGLHCDFACLMFKHLV-------HKPAEQRVREIITNAVRIEQEFLTEALPVKLIGMNC 318 DE +H F ++ + + + ++ +E++ IE + E IG+ Sbjct: 194 DESIHGVFVGILAQQIFAELSAEEQQEVQKETQELLMELYEIEMAYTEEIYTS--IGL-V 250 Query: 319 TLMKQYIEFVADRLMLELGFNKIFRVE--NP 347 + +++ + A++ ++ LG F E NP Sbjct: 251 EDVNRFVRYNANKGLMNLGLEPKFEEEEINP 281 >4N83-A nrPDB Length = 319 Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 65/291 (22%), Positives = 129/291 (44%), Gaps = 18/291 (6%) Query: 95 YKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQEV 154 ++K FW + LS D+ W L E+ + V D + +E+ V+ ++V Sbjct: 22 WEKLTEQFWLDTRIPLSNDLDDWRKLSHKEKDLVGKVFGGLTLLDTLQSESGVDALRKDV 81 Query: 155 QVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWALRW 214 + + ME++H++ YS + T + E + +F T P ++KKA+ Sbjct: 82 RTAHEEAVFNNIQFMESVHAKSYSSIFST-LNTKSEIDEIFAWTNTNPYLQKKAEIINEI 140 Query: 215 IGDKEATYGERVVAFAAVEG-IFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDF 273 + A E+ +A +E +F+SG F +++L L + +LI RDE +H + Sbjct: 141 YLNGTAL--EKKIASVFLETFLFYSGFFTPLYYLGNNKL-ANVAEIIKLIIRDESVHGTY 197 Query: 274 ACLMFKHLVHKPAE---QRVREIITNAVRI---EQEFLTEALPVKLIGMNCTLMKQYIEF 327 F+ ++ E ++++E + + + +E TE+L +G +K ++ + Sbjct: 198 IGYKFQLAFNELPEDEQEKLKEWMYDLLYTLYENEEGYTESL-YDTVGW-TEEVKTFLRY 255 Query: 328 VADRLMLELGFNKIFRVE----NPFDFMENISLEGKTNFFEKRVGEYQRMG 374 A++ ++ LG + +F NP M IS + F +VG +G Sbjct: 256 NANKALMNLGQDPLFPDSADDVNPI-VMNGISTGTSNHDFFSQVGNGYLLG 305 >6QRZ-A nrPDB Length = 328 Score = 55.1 bits (131), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 55/216 (25%), Positives = 93/216 (43%), Gaps = 21/216 (9%) Query: 93 QMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQ 152 ++Y+ + FW ++D SKD + W+ L DE++++ ++++ F A + V ++ S Sbjct: 47 KLYQIGKRLFWDPAKIDFSKDKEDWKKLSKDEKNYLLNIVSLFMAGEEAVAVDITPLIS- 105 Query: 153 EVQVTEAR---CFYGFQIAMENI-HSEMYSLLIDTY-IKD-----PKEREYLFNAI--ET 200 + E R Y Q A E H+E + D+ I D E + I E Sbjct: 106 -TMINEGRVEDVIYLEQFAFEEAKHAEAFRRFCDSLEINDDLTIFTTEYNPWYQKIFYEE 164 Query: 201 MPCV--KKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTF 258 +P V K + D + + TY V AA G +F IF +MPGL+ Sbjct: 165 LPSVMWKLRVDPSPENLAVAVTTYNLYVEGVAAESGY---KTFKHIF--NSLNIMPGLSK 219 Query: 259 SNELISRDEGLHCDFACLMFKHLVHKPAEQRVREII 294 + LI+ DE H + + L+ + E R+ I Sbjct: 220 TVNLIATDESRHIAYGTYLITRLIVENGESIYRKAI 255 >2BQ1-I nrPDB Length = 319 Score = 50.8 bits (120), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 56/260 (21%), Positives = 105/260 (40%), Gaps = 13/260 (5%) Query: 93 QMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQ 152 +++ + ++FW E+V LS DI W+ L E+ V D I N Sbjct: 21 EVWNRLTSNFWLPEKVPLSNDIPAWQTLSAAEQQLTIRVFTGLTLLDTIQNIAGAPSLMA 80 Query: 153 EVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWAL 212 + ME +H+ YS + T + KE + + E P +++KA L Sbjct: 81 DAITPHEEAVLSNISFMEAVHARSYSSIFSTLCQ-TKEVDAAYAWSEENPPLQRKAQIIL 139 Query: 213 -RWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHC 271 ++ D+ ++ +A +E F F + RG + LI RDE +H Sbjct: 140 AHYVSDEPL---KKKIASVFLESFLFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHG 196 Query: 272 DFACLMFKHLVHKPAEQRVREIITNAVRIEQEF------LTEALPVKLIGMNCTLMKQYI 325 + ++ + K + E+ A+ + E TEAL + +N +K ++ Sbjct: 197 YYIGYKYQIALQKLSAIEREELKLFALDLLMELYDNEIRYTEALYAETGWVND--VKAFL 254 Query: 326 EFVADRLMLELGFNKIFRVE 345 + A++ ++ LG+ +F E Sbjct: 255 CYNANKALMNLGYEALFPPE 274 >3MJO-A nrPDB Length = 296 Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 43/200 (21%), Positives = 77/200 (38%), Gaps = 3/200 (1%) Query: 93 QMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQ 152 +++ + +FW E++ +S DIQ W + P E+ V D I Sbjct: 30 EVWDRLTGNFWLPEKIPVSNDIQSWNKMTPQEQLATMRVFTGLTLLDTIQGTVGAISLLP 89 Query: 153 EVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWAL 212 + + Y ME++H++ YS + T P+ E F E +++KA + Sbjct: 90 DAETMHEEAVYTNIAFMESVHAKSYSNIFMTLASTPQINE-AFRWSEENENLQRKAKIIM 148 Query: 213 RWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCD 272 + + ++ VA +E F F +L R + LI RDE +H Sbjct: 149 SYYNGDDPL--KKKVASTLLESFLFYSGFYLPMYLSSRAKLTNTADIIRLIIRDESVHGY 206 Query: 273 FACLMFKHLVHKPAEQRVRE 292 + ++ V K +E E Sbjct: 207 YIGYKYQQGVKKLSEAEQEE 226 >3DHZ-A nrPDB Length = 329 Score = 48.5 bits (114), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 43/200 (21%), Positives = 77/200 (38%), Gaps = 3/200 (1%) Query: 93 QMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQ 152 +++ + +FW E++ +S DIQ W + P E+ V D I Sbjct: 31 EVWDRLTGNFWLPEKIPVSNDIQSWNKMTPQEQLATMRVFTGLTLLDTIQGTVGAISLLP 90 Query: 153 EVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWAL 212 + + Y ME++H++ YS + T P+ E F E +++KA + Sbjct: 91 DAETMHEEAVYTNIAFMESVHAKSYSNIFMTLASTPQINE-AFRWSEENENLQRKAKIIM 149 Query: 213 RWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCD 272 + + ++ VA +E F F +L R + LI RDE +H Sbjct: 150 SYYNGDDPL--KKKVASTLLESFLFYSGFYLPMYLSSRAKLTNTADIIRLIIRDESVHGY 207 Query: 273 FACLMFKHLVHKPAEQRVRE 292 + ++ V K +E E Sbjct: 208 YIGYKYQQGVKKLSEAEQEE 227 >6EBP-A nrPDB Length = 355 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 58/294 (19%), Positives = 111/294 (37%), Gaps = 53/294 (18%) Query: 93 QMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNE-NLVERFS 151 +++ + +FW E + +S D+ W L D + I+ D + + V + Sbjct: 57 EVWNRVTQNFWLPENIPVSNDLPSWNELDDDWQQLITRTFTGLTLLDTVQSSIGDVAQIK 116 Query: 152 QEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWA 211 + E + F M +H+ + + T C ++ + A Sbjct: 117 NSLTEQEQVIYANFAF-MVGVHARSFGTIFSTL------------------CTSEQIEEA 157 Query: 212 LRWIGDKEATYG---------------ERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGL 256 W+ D EA + +A A + G G F F+L RG +P Sbjct: 158 HEWVVDNEALQARPKALIPFYTADDPLKSKIAAALMPGFLLYGGFYLPFYLSARGKLPNT 217 Query: 257 TFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRIEQEFLTEALPVKLIGM 316 + LI RD+ +H ++ ++ V K + ++ E+ ++F+ + L K+IG+ Sbjct: 218 SDIIRLILRDKVIHNFYSGYKYQLKVAKLSPEKQAEM--------KQFVFDLLD-KMIGL 268 Query: 317 NCTLMKQ-YIEF-VADRLMLELGFNKIFRVENPFDFMENISLEGKTNFFEKRVG 368 T + Q Y F +AD + F + N F++N+ E E R+ Sbjct: 269 EKTYLHQLYDGFGLADEAIR-------FSLYNAGKFLQNLGYESPFTKEETRIA 315 >4AC8-A nrPDB Length = 323 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 59/236 (25%), Positives = 98/236 (41%), Gaps = 38/236 (16%) Query: 93 QMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQ 152 +++ A FW ++D ++D WE L DER + + + F A + V E+ ++ F Sbjct: 31 KLFAGGNAKFWHPADIDFTRDRADWEKLSDDERDYATRLCTQFIAGEEAVTED-IQPFMS 89 Query: 153 EVQVTEARC---FYGFQIAMENI-HSEMYSLLIDT---------YIKDPKEREYLFNAIE 199 ++ E R Y Q A E H++++ + +D Y+ D +F A E Sbjct: 90 AMRA-EGRLADEMYLTQFAFEEAKHTQVFRMWLDAVGISEDLHRYLDDLPAYRQIFYA-E 147 Query: 200 TMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIF-FSGSFASIFWLK---KRGLMPG 255 C+ AL A V VEG+ +G +A W K +R ++PG Sbjct: 148 LPECLN-----ALSADPSPAAQVRASVTYNHIVEGMLALTGYYA---WHKICVERAILPG 199 Query: 256 LTFSNELISRDEGLHC---DFACLMFKHLVHKPA-----EQRVREIITNAVRIEQE 303 + I DE H F C +H+ A E R+ E+I A+R+ +E Sbjct: 200 MQELVRRIGDDERRHMAWGTFTCR--RHVAADDANWTVFETRMNELIPLALRLIEE 253 >6GP2-A nrPDB Length = 345 Score = 42.0 bits (97), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 51/258 (19%), Positives = 100/258 (38%), Gaps = 9/258 (3%) Query: 93 QMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGI-VNENLVERFS 151 +++ + +FW E++ +S D+ W L P+ + I+ D I V + Sbjct: 47 EVWNRITQNFWLPEKIPVSNDLTSWRTLTPEWQELITRTFTGLTLLDTIQATVGDVAQVP 106 Query: 152 QEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWA 211 + E + F M +H+ + + T + E I T ++ Sbjct: 107 NSLTDHEQVIYTNFAF-MVAVHARSFGSIFSTLCSSEQIEEAHEWVINTETLQERAKALI 165 Query: 212 LRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHC 271 ++ D + VA A + G G F F+L RG +P + LI RD+ +H Sbjct: 166 PYYVNDDPL---KSKVAAALMPGFLLYGGFYLPFYLSARGKLPNTSDIIRLILRDKVIHN 222 Query: 272 DFACLMFKHLVHKPAEQRVREIITNAVRIEQEFLT-EALPVKLIGMNCTLMKQYIEFV-- 328 ++ ++ V K + ++ E+ ++ E + E +K + + L I F Sbjct: 223 YYSGYKYQKKVAKLSPEKQAEMKEFVFKLLYELIDLEKAYLKELYEDFGLADDAIRFSVY 282 Query: 329 -ADRLMLELGFNKIFRVE 345 A + + LG++ F E Sbjct: 283 NAGKFLQNLGYDSPFTEE 300 >3N37-A nrPDB Length = 319 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 49/257 (19%), Positives = 94/257 (36%), Gaps = 7/257 (2%) Query: 93 QMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQ 152 +++ + ++FW E+V LS DI W+ L E+ V D + N Sbjct: 21 EVWNRLTSNFWLPEKVPLSNDIPAWQTLTVVEQQLTMRVFTGLTLLDTLQNVIGAPSLMP 80 Query: 153 EVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWAL 212 + ME +H+ YS + T + + E P +K Sbjct: 81 DALTPHEEAVLSNISFMEAVHARSYSSIFSTLCQTKDVDAAYAWSEENAPLQRKAQIIQQ 140 Query: 213 RWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCD 272 + GD ++ +A +E F F + RG + LI RDE +H Sbjct: 141 HYRGDDPL---KKKIASVFLESFLFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHGY 197 Query: 273 FACLMFKHLVHKPAEQRVREIITNAVRIEQEFLTEALPV--KLIGMN--CTLMKQYIEFV 328 + ++ + K + + E+ + A + E L +L +K ++ + Sbjct: 198 YIGYKYQKNMEKISLGQREELKSFAFDLLLELYDNELQYTDELYAETPWADDVKAFLCYN 257 Query: 329 ADRLMLELGFNKIFRVE 345 A++ ++ LG+ +F E Sbjct: 258 ANKALMNLGYEPLFPAE 274 >6CWO-A nrPDB Length = 344 Score = 36.2 bits (82), Expect = 0.026, Method: Compositional matrix adjust. Identities = 50/242 (20%), Positives = 98/242 (40%), Gaps = 34/242 (14%) Query: 85 PIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEA-LKPDERHFISHVLAFFAASDGIVN 143 P EY ++ Q + ++W EVD + D Q + A L E+ + + L A + V Sbjct: 32 PFEYPEVLQFTEAINKAYWVHTEVDFTADTQDFHAHLSLAEKTAVKNSLLAIAQIEVAVK 91 Query: 144 E---NLVERFSQE----VQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFN 196 N+ E F + + T A C E HSE YS L++ + + F Sbjct: 92 SFWGNIYEHFPKPEFNGLGSTFAEC--------EFRHSEAYSRLLEVLGYNDE-----FE 138 Query: 197 AIETMPCVKKKADWALRWIGDKEA----TYGERVVAFAA-VEGIFFSGSFASIFWLKK-R 250 + +P ++++ D+ + D ++ Y ++ F+ +E + FA + + + Sbjct: 139 KLLDVPVIRRRVDYLSNVLKDTKSQDNRKYMVSLILFSILIENVSLFSQFAILLSFTRFK 198 Query: 251 GLMPGLTFSNELISRDEGLHCDFACLM-------FKHLVHKPAEQRVREIITNAVRIEQE 303 G M ++ S DE +H + + F + VRE + +++ +E + Sbjct: 199 GYMKNVSNIIAWTSIDEQIHANGGIYIINKIREEFPDYFDEETLALVRETVKDSIAVESD 258 Query: 304 FL 305 L Sbjct: 259 IL 260 >6CWP-A nrPDB Length = 307 Score = 35.8 bits (81), Expect = 0.030, Method: Compositional matrix adjust. Identities = 50/242 (20%), Positives = 98/242 (40%), Gaps = 34/242 (14%) Query: 85 PIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEA-LKPDERHFISHVLAFFAASDGIVN 143 P EY ++ Q + ++W EVD + D Q + A L E+ + + L A + V Sbjct: 19 PFEYPEVLQFTEAINKAYWVHTEVDFTADTQDFHAHLSLAEKTAVKNSLLAIAQIEVAVK 78 Query: 144 E---NLVERFSQE----VQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFN 196 N+ E F + + T A C E HSE YS L++ + + F Sbjct: 79 SFWGNIYEHFPKPEFNGLGSTFAEC--------EFRHSEAYSRLLEVLGYNDE-----FE 125 Query: 197 AIETMPCVKKKADWALRWIGDKEA----TYGERVVAFAA-VEGIFFSGSFASIFWLKK-R 250 + +P ++++ D+ + D ++ Y ++ F+ +E + FA + + + Sbjct: 126 KLLDVPVIRRRVDYLSNVLKDTKSQDNRKYMVSLILFSILIENVSLFSQFAILLSFTRFK 185 Query: 251 GLMPGLTFSNELISRDEGLHCDFACLM-------FKHLVHKPAEQRVREIITNAVRIEQE 303 G M ++ S DE +H + + F + VRE + +++ +E + Sbjct: 186 GYMKNVSNIIAWTSIDEQIHANGGIYIINKIREEFPDYFDEETLALVRETVKDSIAVESD 245 Query: 304 FL 305 L Sbjct: 246 IL 247 >5OOM-5 nrPDB Length = 423 Score = 34.3 bits (77), Expect = 0.11, Method: Compositional matrix adjust. Identities = 28/114 (24%), Positives = 46/114 (40%), Gaps = 12/114 (10%) Query: 209 DWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMP-GLTFSNELISRDE 267 +W +R E +RV +E I F+G + WL + P + + R Sbjct: 32 EWGVRSTRKSEPPPLDRVYEIPGLEPITFAGKMHFVPWLARPIFPPWDRGYKDPRFYRSP 91 Query: 268 GLH-----CDFACLMFKHLVHKPAEQRVREIITNAVRIEQEFLTEALPVKLIGM 316 LH D AC +F H R+ E + A+ + + L E LP K++ + Sbjct: 92 PLHEHPLYKDQACYIFHHRC------RLLEGVKQALWLTKTKLIEGLPEKVLSL 139 >5OMK-A nrPDB Length = 316 Score = 33.5 bits (75), Expect = 0.17, Method: Compositional matrix adjust. Identities = 58/306 (18%), Positives = 134/306 (43%), Gaps = 45/306 (14%) Query: 89 HDIWQMYKKAEASF-WTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLV 147 H ++++Y+KA+ + W ++D S+D + + +L +E+ ++A F+A + V +++ Sbjct: 32 HPMFKLYEKAKRNGKWNPADIDFSQDQKDFASLTSEEKISALPLVAGFSAGEEAVTLDIL 91 Query: 148 ---ERFSQEVQVTEARCFYGFQIAMENIHSEMYS----------LLIDTYIKDPKEREYL 194 +++ ++ + F + E H EM+S + + + D +R + Sbjct: 92 PMAHALARQGRLEDVLFLTTF-MHDEAKHVEMFSRWQQAVGIGQMDLSVFHNDHYKRIFY 150 Query: 195 FNAIETMPCVKKK--ADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGL 252 E +P + AD + + Y V A G + +F I+ KK GL Sbjct: 151 ----EALPEAMNRLYADDSPEAVIRAATVYNMIVEGTLAESGYY---TFRQIY--KKAGL 201 Query: 253 MPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRIEQEFLTEALPVK 312 PGL + ++ DEG H F + +V++ ++R E+ ++ E P Sbjct: 202 FPGLLQGIDYLNMDEGRHIQFGIYTIQRIVNE--DERYYELFIR-------YMDELWP-H 251 Query: 313 LIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISLEGKTNFFEKRVGEYQR 372 +IG Y++++ + + + + +E +D + + ++ + N +K++ +R Sbjct: 252 VIG--------YVDYLTELGKRQQQLARTYALEIDYDLLRHYVIK-QFNLRKKQISRTKR 302 Query: 373 MGVMSN 378 + V+ Sbjct: 303 VDVVEG 308 >5OLK-A nrPDB Length = 430 Score = 32.7 bits (73), Expect = 0.27, Method: Compositional matrix adjust. Identities = 39/204 (19%), Positives = 84/204 (41%), Gaps = 13/204 (6%) Query: 79 RRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWE-ALKPDERHFISHVLAFFAA 137 +R + P EY ++ + S+W E + + DIQ ++ L ER I + + + Sbjct: 112 KRINLKPYEYPELNEYVAAIRHSYWIHTEFNFTSDIQDFKTGLSEVERSAIKNTMLAISQ 171 Query: 138 SDGIVNE---NLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLL-IDTYIKDPKEREY 193 + V ++ R + F ++ + +S + +L ++ K+ K++ Sbjct: 172 IEVAVKTFWGDVHHRLPKPEIAAVGATFAESEVRHHDAYSHLLEILGLNEEFKELKKKPV 231 Query: 194 LFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAA-VEGIFFSGSFASIFWLKK-RG 251 + + + K A D + Y E ++ FA +E + F I K + Sbjct: 232 IMKRVHYLETSLKHAK------SDDDREYTESILLFALFIEHVSLFSQFLIIMAFNKHKN 285 Query: 252 LMPGLTFSNELISRDEGLHCDFAC 275 ++ G++ + E S++E +H DF Sbjct: 286 MLKGISNAVEATSKEEQIHGDFGV 309 >3QD9-A nrPDB Length = 470 Score = 32.0 bits (71), Expect = 0.44, Method: Compositional matrix adjust. Identities = 20/66 (30%), Positives = 28/66 (42%), Gaps = 10/66 (15%) Query: 234 GIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREI 293 GI F GS ++ W RG P G C L+ V+ PA++ V E+ Sbjct: 275 GIPFDGSPRNVRWRTCRGSSPQY----------RGFPCGMWLLLHALTVNTPADRNVLEV 324 Query: 294 ITNAVR 299 I N +R Sbjct: 325 IQNYIR 330 >3V4P-B nrPDB Length = 503 Score = 30.8 bits (68), Expect = 1.1, Method: Compositional matrix adjust. Identities = 15/46 (32%), Positives = 23/46 (50%), Gaps = 1/46 (2%) Query: 339 NKIFRVENPFDFMENISLEGKTNFFEKRVGEYQRMGVMSNSTENSF 384 ++ R ++PF F +SL G FE+ VG G + +S E F Sbjct: 199 TRLERCQSPFSFHHVLSLTGDAQAFEREVGRQSVSGNL-DSPEGGF 243 >4FL0-A nrPDB Length = 456 Score = 28.9 bits (63), Expect = 4.0, Method: Compositional matrix adjust. Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 9/70 (12%) Query: 327 FVAD-------RLMLELGFNKIFRVENPF--DFMENISLEGKTNFFEKRVGEYQRMGVMS 377 FV+D RL L LG N V++P ++++ + G+T F ++ +YQ + M Sbjct: 137 FVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMP 196 Query: 378 NSTENSFTLD 387 NSF D Sbjct: 197 CGPNNSFFPD 206 >6CVC-A nrPDB Length = 433 Score = 28.9 bits (63), Expect = 4.3, Method: Compositional matrix adjust. Identities = 23/89 (25%), Positives = 39/89 (43%), Gaps = 11/89 (12%) Query: 94 MYKKAEASFWTAEEV-DLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQ 152 + ++A SFW E+ L+ HW K D+ HF S F +S IV + Sbjct: 50 LRREAPISFWPPIELAGLTAGKGHWALTKHDDIHFASRHPEIFHSSPNIVIHD------- 102 Query: 153 EVQVTEARCFYGFQIAMENI-HSEMYSLL 180 Q E ++G I +++ H + S++ Sbjct: 103 --QTPELAEYFGSMIVLDDPRHQRLRSIV 129 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1H0O-A nrPDB 563 e-161 2UW2-A nrPDB 466 e-132 1SMQ-A nrPDB 459 e-129 3HF1-A nrPDB 453 e-128 4DJN-A nrPDB 413 e-116 3OLJ-A nrPDB 408 e-114 2P1I-A nrPDB 389 e-109 1SMS-A nrPDB 360 e-100 2O1Z-A nrPDB 343 7e-95 4M1I-A nrPDB 296 9e-81 2BQ1-I nrPDB 266 1e-71 4DR0-A nrPDB 265 2e-71 4N83-A nrPDB 264 4e-71 2RCC-A nrPDB 258 4e-69 4BMQ-A nrPDB 254 5e-68 1PIY-A nrPDB 253 1e-67 3DHZ-A nrPDB 250 7e-67 3MJO-A nrPDB 248 4e-66 6GP2-A nrPDB 245 2e-65 6EBP-A nrPDB 233 9e-62 4AC8-A nrPDB 165 3e-41 6QRZ-A nrPDB 152 3e-37 Sequences not found previously or not previously below threshold: 3N37-A nrPDB 252 2e-67 1UZR-A nrPDB 238 4e-63 5OMK-A nrPDB 95 5e-20 5OLK-A nrPDB 92 4e-19 6CWO-A nrPDB 91 9e-19 6CWP-A nrPDB 84 7e-17 3N1X-A nrPDB 39 0.003 3Q3N-A nrPDB 36 0.023 1ZA0-A nrPDB 36 0.025 5VQE-A nrPDB 34 0.12 3CHI-A nrPDB 34 0.16 5TW7-A nrPDB 32 0.43 5EUT-A nrPDB 32 0.45 4HNE-A nrPDB 32 0.53 5K52-A nrPDB 32 0.57 3ETC-A nrPDB 31 1.2 2FNQ-A nrPDB 30 1.8 1GPM-A nrPDB 30 2.1 3WCH-A nrPDB 30 2.5 6AH0-w nrPDB 29 3.4 5JRE-A nrPDB 29 3.6 5FIP-A nrPDB 29 4.0 3DFA-A nrPDB 29 5.2 5JD3-A nrPDB 28 5.8 3B55-A nrPDB 28 7.7 3NCG-A nrPDB 28 8.1 3UAN-A nrPDB 27 9.6 4EP1-A nrPDB 27 9.9 >1H0O-A nrPDB Length = 390 Score = 563 bits (1451), Expect = e-161, Method: Composition-based stats. Identities = 390/390 (100%), Positives = 390/390 (100%) Query: 1 MLSVRTPLATIADQQQLQLSPLKRLTLADKENTPPTLSSTRVLASKAARRIFQDSAELES 60 MLSVRTPLATIADQQQLQLSPLKRLTLADKENTPPTLSSTRVLASKAARRIFQDSAELES Sbjct: 1 MLSVRTPLATIADQQQLQLSPLKRLTLADKENTPPTLSSTRVLASKAARRIFQDSAELES 60 Query: 61 KAPTNPSVEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEAL 120 KAPTNPSVEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEAL Sbjct: 61 KAPTNPSVEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEAL 120 Query: 121 KPDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLL 180 KPDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLL Sbjct: 121 KPDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLL 180 Query: 181 IDTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGS 240 IDTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGS Sbjct: 181 IDTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGS 240 Query: 241 FASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRI 300 FASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRI Sbjct: 241 FASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRI 300 Query: 301 EQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISLEGKT 360 EQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISLEGKT Sbjct: 301 EQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISLEGKT 360 Query: 361 NFFEKRVGEYQRMGVMSNSTENSFTLDADF 390 NFFEKRVGEYQRMGVMSNSTENSFTLDADF Sbjct: 361 NFFEKRVGEYQRMGVMSNSTENSFTLDADF 390 >2UW2-A nrPDB Length = 332 Score = 466 bits (1199), Expect = e-132, Method: Composition-based stats. Identities = 310/325 (95%), Positives = 321/325 (98%) Query: 66 PSVEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEALKPDER 125 P VEDEPLLRENPRRFV+FPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWE+LKP+ER Sbjct: 8 PGVEDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEER 67 Query: 126 HFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYI 185 +FISHVLAFFAASDGIVNENLVERFSQEVQ+TEARCFYGFQIAMENIHSEMYSLLIDTYI Sbjct: 68 YFISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYI 127 Query: 186 KDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIF 245 KDPKERE+LFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIF Sbjct: 128 KDPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIF 187 Query: 246 WLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRIEQEFL 305 WLKKRG MPGLTFSNELISRDEGLHCDFACLMFKHLVHKP+E+RVREII NAVRIEQEFL Sbjct: 188 WLKKRGPMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFL 247 Query: 306 TEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISLEGKTNFFEK 365 TEALPVKLIGMNCTLMKQYIEFVADRLMLELGF+K+FRVENPFDFMENISLEGKTNFFEK Sbjct: 248 TEALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGKTNFFEK 307 Query: 366 RVGEYQRMGVMSNSTENSFTLDADF 390 RVGEYQRMGVMS+ TENSFTLDADF Sbjct: 308 RVGEYQRMGVMSSPTENSFTLDADF 332 >1SMQ-A nrPDB Length = 399 Score = 459 bits (1180), Expect = e-129, Method: Composition-based stats. Identities = 237/392 (60%), Positives = 289/392 (73%), Gaps = 21/392 (5%) Query: 3 SVRTPLATIADQQQLQLSPLKRLTLADKENTPPTLSSTRVLASKAARRIFQDSAELESKA 62 ++ L T+ ++ +++ LK D EN L S +V K E+E Sbjct: 25 NLNKELETLREENRVKSDMLKEKLSKDAENHKAYLKSHQVHRHKLK--------EME--- 73 Query: 63 PTNPSVEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWE-ALK 121 ++EPLL E+ R V+FPI+YH+IWQ YK+AEASFWTAEE+DLSKDI W + Sbjct: 74 ------KEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMN 127 Query: 122 PDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLI 181 +ER FIS VLAFFAASDGIVNENLVE FS EVQ+ EA+ FYGFQI +ENIHSE YSLLI Sbjct: 128 ENERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLI 187 Query: 182 DTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSF 241 DTYIKDPKE E+LFNAI T+P + +KA+WALRWI D +A +GER+VAFA++EG+FFSGSF Sbjct: 188 DTYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSF 247 Query: 242 ASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRIE 301 ASIFWLKKRG+MPGLTFSNELI RDEGLH DFACL+F HL +KP V +I+T AV IE Sbjct: 248 ASIFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIE 307 Query: 302 QEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISLEGKTN 361 Q + +ALPV L+GMN LM QY+EFVADRL++ G K ++VENPFDFMENISL GKTN Sbjct: 308 QRYFLDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENISLAGKTN 367 Query: 362 FFEKRVGEYQRMGVMSNSTEN---SFTLDADF 390 FFEKRV +YQ+ GVMS ST+ +FT + DF Sbjct: 368 FFEKRVSDYQKAGVMSKSTKQEAGAFTFNEDF 399 >3HF1-A nrPDB Length = 351 Score = 453 bits (1164), Expect = e-128, Method: Composition-based stats. Identities = 268/334 (80%), Positives = 307/334 (91%), Gaps = 3/334 (0%) Query: 60 SKAPTNPS---VEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQH 116 S + TN S +EPLLR++ RRFV+FPI+Y DIW+MYK+A+ASFWTAEEVDLSKD+ H Sbjct: 18 SSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPH 77 Query: 117 WEALKPDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEM 176 W LK DE++FISH+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +EN+HSEM Sbjct: 78 WNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEM 137 Query: 177 YSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIF 236 YSLLIDTYI+DPK+RE+LFNAIETMP VKKKADWALRWI D+++T+GERVVAFAAVEG+F Sbjct: 138 YSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVF 197 Query: 237 FSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITN 296 FSGSFA+IFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMF++LV+KP+E+RVREII + Sbjct: 198 FSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVD 257 Query: 297 AVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISL 356 AV+IEQEFLTEALPV LIGMNC LMKQYIEFVADRL++ELGF+K+F+ ENPFDFMENISL Sbjct: 258 AVKIEQEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISL 317 Query: 357 EGKTNFFEKRVGEYQRMGVMSNSTENSFTLDADF 390 EGKTNFFEKRV EYQR VM+ +T+N FTLDADF Sbjct: 318 EGKTNFFEKRVSEYQRFAVMAETTDNVFTLDADF 351 >4DJN-A nrPDB Length = 311 Score = 413 bits (1061), Expect = e-116, Method: Composition-based stats. Identities = 247/305 (80%), Positives = 283/305 (92%), Gaps = 3/305 (0%) Query: 60 SKAPTNPS---VEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQH 116 S + TN S +EPLLR++ RRFV+FPI+Y DIW+MYK+A+ASFWTAEEVDLSKD+ H Sbjct: 7 SSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPH 66 Query: 117 WEALKPDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEM 176 W LK DE++FISH+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +EN+HSEM Sbjct: 67 WNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEM 126 Query: 177 YSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIF 236 YSLLIDTYI+DPK+RE+LFNAIETMP VKKKADWALRWI D+++T+GERVVAFAAVEG+F Sbjct: 127 YSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVF 186 Query: 237 FSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITN 296 FSGSFA+IFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMF++LV+KP+E+RVREII + Sbjct: 187 FSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVD 246 Query: 297 AVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISL 356 AV+IEQEFLTEALPV LIGMNC LMKQYIEFVADRL++ELGF+K+F+ ENPFDFMENISL Sbjct: 247 AVKIEQEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISL 306 Query: 357 EGKTN 361 EGKTN Sbjct: 307 EGKTN 311 >3OLJ-A nrPDB Length = 286 Score = 408 bits (1047), Expect = e-114, Method: Composition-based stats. Identities = 273/285 (95%), Positives = 283/285 (99%) Query: 67 SVEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEALKPDERH 126 VEDEPLLRENPRRFV+FPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWE+LKP+ER+ Sbjct: 2 GVEDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERY 61 Query: 127 FISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIK 186 FISHVLAFFAASDGIVNENLVERFSQEVQ+TEARCFYGFQIAMENIHSEMYSLLIDTYIK Sbjct: 62 FISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIK 121 Query: 187 DPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFW 246 DPKERE+LFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFW Sbjct: 122 DPKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFW 181 Query: 247 LKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRIEQEFLT 306 LKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKP+E+RVREII NAVRIEQEFLT Sbjct: 182 LKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLT 241 Query: 307 EALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFM 351 EALPVKLIGMNCTLMKQYIEFVADRLMLELGF+K+FRVENPFDFM Sbjct: 242 EALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFM 286 >2P1I-A nrPDB Length = 349 Score = 389 bits (1000), Expect = e-109, Method: Composition-based stats. Identities = 192/334 (57%), Positives = 242/334 (72%), Gaps = 1/334 (0%) Query: 57 ELESKAPTNPSVEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQH 116 E E +E +L + RF + PI Y ++W YKKAEASFWTAEE+DLS D++ Sbjct: 17 EKEFSDFQKSKESNEKILNKESNRFTLHPIMYPEVWNFYKKAEASFWTAEEIDLSSDLKD 76 Query: 117 WEALKPDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEM 176 +E L +E+HFI HVLAFFAASDGIV ENL +F +EV++ EA+ FY FQIA+ENIHSE Sbjct: 77 FEKLNVNEKHFIKHVLAFFAASDGIVLENLASKFLREVEIIEAKKFYSFQIAVENIHSET 136 Query: 177 YSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIF 236 YSLLID YIKD KER LF+AIE +P +K KA WA +WI D + + ER+VA A VEGI Sbjct: 137 YSLLIDNYIKDEKERLNLFHAIENIPAIKNKALWAAKWINDTNS-FAERIVANACVEGIL 195 Query: 237 FSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITN 296 FSGSF +IFW KK+ + GLTFSNELISRDEGLH DF CL++ L +K E V+ I+ Sbjct: 196 FSGSFCAIFWFKKQNKLHGLTFSNELISRDEGLHTDFNCLIYSLLENKLPENVVQNIVKE 255 Query: 297 AVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISL 356 AV +E+ F+ E+LP LIGMN LM QYIEFVADRL+ LG +K+F +NPF++M+ ISL Sbjct: 256 AVEVERSFICESLPCDLIGMNSRLMSQYIEFVADRLLECLGCSKVFHSKNPFNWMDLISL 315 Query: 357 EGKTNFFEKRVGEYQRMGVMSNSTENSFTLDADF 390 +GKTNFFEKRV +YQ+ GVM+ E F+L+ DF Sbjct: 316 QGKTNFFEKRVADYQKSGVMAQRKEQVFSLNTDF 349 >1SMS-A nrPDB Length = 345 Score = 360 bits (924), Expect = e-100, Method: Composition-based stats. Identities = 159/334 (47%), Positives = 225/334 (67%), Gaps = 3/334 (0%) Query: 59 ESKAPTNPSVEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWE 118 + + + +DE LL EN RRFV+FPI+YH+IW YKK EASFWTAEE++L+KD + ++ Sbjct: 13 KERHDMKEAEKDEILLMENSRRFVMFPIKYHEIWAAYKKVEASFWTAEEIELAKDTEDFQ 72 Query: 119 ALKPDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYS 178 L D++ +I ++LA +SD +VN+ L+E FS ++Q E + FYGFQI MENI+SE+YS Sbjct: 73 KLTDDQKTYIGNLLALSISSDNLVNKYLIENFSAQLQNPEGKSFYGFQIMMENIYSEVYS 132 Query: 179 LLIDTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFS 238 +++D + KDPK LF I +P VK KA + RWI + ++ Y ER+VAFAA EGIF + Sbjct: 133 MMVDAFFKDPKNI-PLFKEIANLPEVKHKAAFIERWISNDDSLYAERLVAFAAKEGIFQA 191 Query: 239 GSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAV 298 G++AS+FWL + +MPGL +N I RD G + DF+CL+F HL KP + + +IIT AV Sbjct: 192 GNYASMFWLTDKKIMPGLAMANRNICRDRGAYTDFSCLLFAHLRTKPNPKIIEKIITEAV 251 Query: 299 RIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISLEG 358 IE+E+ + +LPV+ GM+ + YIEFVAD L+ G K + NPF+FME+++ G Sbjct: 252 EIEKEYYSNSLPVEKFGMDLKSIHTYIEFVADGLLQGFGNEKYYNAVNPFEFMEDVATAG 311 Query: 359 KTNFFEKRVGEYQRMGVMSNSTENS--FTLDADF 390 KT FFEK+V +YQ+ MS S S D DF Sbjct: 312 KTTFFEKKVSDYQKASDMSKSATPSKEINFDDDF 345 >2O1Z-A nrPDB Length = 311 Score = 343 bits (880), Expect = 7e-95, Method: Composition-based stats. Identities = 170/283 (60%), Positives = 213/283 (75%), Gaps = 1/283 (0%) Query: 70 DEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFIS 129 +E +L + RF ++PI Y D+W YKKAEASFWTAEE+DLS D++ +E L +E+HFI Sbjct: 29 NEKILSKETDRFTLYPILYPDVWDFYKKAEASFWTAEEIDLSSDLKDFEKLNDNEKHFIK 88 Query: 130 HVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPK 189 HVLAFFAASDGIV ENL +F ++V++TEA+ FY FQIA+ENIHSE YSLLID YIKD K Sbjct: 89 HVLAFFAASDGIVLENLASKFLRQVKITEAKKFYAFQIAVENIHSETYSLLIDNYIKDEK 148 Query: 190 EREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKK 249 ER LF+AIE +P VK KA WA +WI D + + ER+VA A VEGI FSGSF +IFW KK Sbjct: 149 ERMNLFHAIENIPAVKNKALWAAKWINDTNS-FAERIVANACVEGILFSGSFCAIFWFKK 207 Query: 250 RGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRIEQEFLTEAL 309 + + GLTFSNELISRDEGLH DF CL++ L +K E+ V+ I+ AV +E+ F+ E+L Sbjct: 208 QNKLHGLTFSNELISRDEGLHTDFNCLIYSLLENKLPEEVVQNIVKEAVEVERSFICESL 267 Query: 310 PVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFME 352 P LIGMN LM QYIEFVADRL+ LG KIF +NPF++M+ Sbjct: 268 PCDLIGMNSRLMSQYIEFVADRLLECLGSPKIFHAKNPFNWMD 310 >4M1I-A nrPDB Length = 366 Score = 296 bits (758), Expect = 9e-81, Method: Composition-based stats. Identities = 90/318 (28%), Positives = 151/318 (47%), Gaps = 26/318 (8%) Query: 83 VFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEA--LKPDERHFISHVLAFFAASDG 140 + PI+Y W+ Y A+ W E+ + KDI+ W++ L DER I L FF+ ++ Sbjct: 51 LVPIKYKWAWEHYLNGCANNWLPTEIPMGKDIELWKSDRLSEDERRVILLNLGFFSTAES 110 Query: 141 IVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIET 200 +V N+V + V EAR + Q E +H+ + + ++ D KE +FNA Sbjct: 111 LVGNNIVLAIFKHVTNPEARQYLLRQAFEEAVHTHTFLYICESLGLDEKE---IFNAYNE 167 Query: 201 MPCVKKKADWALRWIGD-------KEATYGER------VVAFAAVEGIFFSGSFASIFWL 247 +K K D+ + G ++ G + V + +EGIFF F I Sbjct: 168 RAAIKAKDDFQMEITGKVLDPNFRTDSVEGLQEFVKNLVGYYIIMEGIFFYSGFVMILSF 227 Query: 248 KKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAE-------QRVREIITNAVRI 300 ++ M G+ + I RDE +H +F + + + E Q + E+I AV + Sbjct: 228 HRQNKMIGIGEQYQYILRDETIHLNFGIDLINGIKEENPEIWTPELQQEIVELIKRAVDL 287 Query: 301 EQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFM-ENISLEGK 359 E E+ + LP ++G+ ++ Y++ +ADR + +G I+ +NPF +M E I L + Sbjct: 288 EIEYAQDCLPRGILGLRASMFIDYVQHIADRRLERIGLKPIYHTKNPFPWMSETIDLNKE 347 Query: 360 TNFFEKRVGEYQRMGVMS 377 NFFE RV EYQ ++ Sbjct: 348 KNFFETRVIEYQHAASLT 365 >2BQ1-I nrPDB Length = 319 Score = 266 bits (679), Expect = 1e-71, Method: Composition-based stats. Identities = 62/304 (20%), Positives = 113/304 (37%), Gaps = 15/304 (4%) Query: 93 QMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQ 152 +++ + ++FW E+V LS DI W+ L E+ V D I N Sbjct: 21 EVWNRLTSNFWLPEKVPLSNDIPAWQTLSAAEQQLTIRVFTGLTLLDTIQNIAGAPSLMA 80 Query: 153 EVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWAL 212 + ME +H+ YS + T + KE + + E P +++KA L Sbjct: 81 DAITPHEEAVLSNISFMEAVHARSYSSIFSTLCQT-KEVDAAYAWSEENPPLQRKAQIIL 139 Query: 213 RWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCD 272 E ++ +A +E F F + RG + LI RDE +H Sbjct: 140 AHYVSDEPL--KKKIASVFLESFLFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHGY 197 Query: 273 FACLMFKHLVHKPAEQRVREIITNAVRIEQEF------LTEALPVKLIGMNCTLMKQYIE 326 + ++ + K + E+ A+ + E TEAL + +N +K ++ Sbjct: 198 YIGYKYQIALQKLSAIEREELKLFALDLLMELYDNEIRYTEALYAETGWVN--DVKAFLC 255 Query: 327 FVADRLMLELGFNKIFRVE----NPFDFMENISLEGKTNFFEKRVGEYQRMGVMSNSTEN 382 + A++ ++ LG+ +F E NP + + F G MG + + Sbjct: 256 YNANKALMNLGYEALFPPEMADVNPAILAALSPNADENHDFFSGSGSSYVMGKTVETEDE 315 Query: 383 SFTL 386 + Sbjct: 316 DWNF 319 >4DR0-A nrPDB Length = 350 Score = 265 bits (678), Expect = 2e-71, Method: Composition-based stats. Identities = 66/313 (21%), Positives = 131/313 (41%), Gaps = 16/313 (5%) Query: 90 DIWQM-YKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVE 148 D QM Y + FW EE+ L+ D+ W+ L +E+ VLA D + Sbjct: 37 DFTQMFYNQNVKQFWLPEEIALNGDLLTWKYLGKNEQDTYMKVLAGLTLLDTEQGNTGMP 96 Query: 149 RFSQEVQVTEARCFYGFQIAMEN-IHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKK 207 ++ V + + F MEN +H++ YS + T E +F ++ ++KK Sbjct: 97 IVAEHVDGHQRKAVLNFMAMMENAVHAKSYSNIFMTLAPTETINE-VFEWVKQNKYLQKK 155 Query: 208 ADWALRWIG----DKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELI 263 A + D E + + +VA +E F F + +G + LI Sbjct: 156 AQMIVGLYKAIQKDDEISLFKAMVASVYLESFLFYSGFYYPLYFYGQGKLMQSGEIINLI 215 Query: 264 SRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRIEQEFLTEALP-----VKLIGMNC 318 RDE +H + L+ + + +K E++ E+ A+ + + L +G++ Sbjct: 216 LRDEAIHGVYVGLLAQEIYNKQTEEKKAELREFAIDLLNQLYENELEYTEDLYDQVGLSH 275 Query: 319 TLMKQYIEFVADRLMLELGFNKIFRVE--NPFDFMENISLEGKTNFFEKRVGEYQRMGVM 376 +K++I + A++ ++ LGF+ F E NP + ++ + K++ F G + + Sbjct: 276 D-VKKFIRYNANKALMNLGFDPYFEEEDINPI-VLNGLNTKTKSHDFFSMKGNGYKKATV 333 Query: 377 SNSTENSFTLDAD 389 ++ F + + Sbjct: 334 EPLKDDDFYFEDE 346 >4N83-A nrPDB Length = 319 Score = 264 bits (675), Expect = 4e-71, Method: Composition-based stats. Identities = 60/302 (19%), Positives = 121/302 (40%), Gaps = 16/302 (5%) Query: 95 YKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQEV 154 ++K FW + LS D+ W L E+ + V D + +E+ V+ ++V Sbjct: 22 WEKLTEQFWLDTRIPLSNDLDDWRKLSHKEKDLVGKVFGGLTLLDTLQSESGVDALRKDV 81 Query: 155 QVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWALRW 214 + + ME++H++ YS + T E + +F T P ++KKA+ Sbjct: 82 RTAHEEAVFNNIQFMESVHAKSYSSIFSTL-NTKSEIDEIFAWTNTNPYLQKKAEIINEI 140 Query: 215 IGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFA 274 + A E+ +A +E F F + + + + +LI RDE +H + Sbjct: 141 YLNGTAL--EKKIASVFLETFLFYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYI 198 Query: 275 CLMFKHLVHKPAEQRVREIITNAVRIE------QEFLTEALPVKLIGMNCTLMKQYIEFV 328 F+ ++ E ++ + +E TE+L +G +K ++ + Sbjct: 199 GYKFQLAFNELPEDEQEKLKEWMYDLLYTLYENEEGYTESLY-DTVGW-TEEVKTFLRYN 256 Query: 329 ADRLMLELGFNKIFRVE----NPFDFMENISLEGKTNFFEKRVGEYQRMGVMSNSTENSF 384 A++ ++ LG + +F NP M IS + F +VG +G + ++ + Sbjct: 257 ANKALMNLGQDPLFPDSADDVNPI-VMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDY 315 Query: 385 TL 386 Sbjct: 316 NY 317 >2RCC-A nrPDB Length = 346 Score = 258 bits (658), Expect = 4e-69, Method: Composition-based stats. Identities = 70/340 (20%), Positives = 147/340 (43%), Gaps = 26/340 (7%) Query: 63 PTNPSVEDEPLLRENPRRFVVFP-IEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEALK 121 T S +L + + + + + +YK A+FWT E+++S D + + L Sbjct: 12 DTTASNASTGILNGKSSNVLNWDDVRFSWAYPLYKNMLANFWTPFEINMSHDAKQFPTLT 71 Query: 122 PDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLI 181 E+ ++ A D + + R ++ + + E +H++ YS ++ Sbjct: 72 ETEQEAFKKIIGLLAFLDSVQT-DYSMRAAEYLTDSSLAALMSVLSFQEVVHNQSYSYVL 130 Query: 182 DTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGD-----KEATYGERVVAFAAVEGIF 236 + + + E +F + +K++ ++ + T+ E +V +EG+ Sbjct: 131 SSLVPKATQDE-IFEYWKHDDVLKERNEFIIDGYEKFVDNPTPKTFLESIVYDVILEGLN 189 Query: 237 FSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVRE---- 292 F FA + L + M + I+RDE LH +FK L+ + E E Sbjct: 190 FYSGFAFFYNLARNQKMVSTSTMINYINRDEQLHVYLFTNIFKELLVEFPELNTEETKTF 249 Query: 293 ---IITNAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRV--ENP 347 + A +E+++ + K+ G+N M+ YI F+A++ ++LG K + NP Sbjct: 250 VKTTLMKAADLEKDWFRYIIGDKIPGINPEDMETYISFIANKRAVQLGMEKPYPEIKHNP 309 Query: 348 FDFM---ENISLEGKTNFFEKRVGEYQRMGVMSNSTENSF 384 ++ E+++ GK++FFE++ +Y ++ S +N F Sbjct: 310 MKWIRAYEDVN-SGKSDFFEQKSRQYAKV-----SADNGF 343 >4BMQ-A nrPDB Length = 322 Score = 254 bits (649), Expect = 5e-68, Method: Composition-based stats. Identities = 66/310 (21%), Positives = 127/310 (40%), Gaps = 21/310 (6%) Query: 94 MYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQE 153 +K+ A FWT EE+ +S D W L +E+ VL D + Sbjct: 17 FWKQNIAQFWTEEEIAVSSDKNTWVQLSKEEQIAYKRVLGGLTLLDTKQGGEGMPLVLVH 76 Query: 154 VQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWA-- 211 ++ +A+ F AME +H++ YS + T +E + +F+ ++ P ++KKA Sbjct: 77 LENLQAKSVLAFMGAMEEVHAKSYSHIFTTLA-TEEEIDDIFDWVDNHPLLEKKAGIITS 135 Query: 212 -LRWIGDKEATYGE---RVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDE 267 R + E T E +VA +E F F +L +G + LI RDE Sbjct: 136 YYRRLLKPEVTKKELYMAMVASVFLESYLFYSGFFYPLYLAGQGKLTASGEIINLIIRDE 195 Query: 268 GLHCDFACLMFKHLVHKPAEQRV-------REIITNAVRIEQEFLTEALPVKLIGMNCTL 320 +H F ++ + + + + + +E++ IE + E IG+ Sbjct: 196 SIHGVFVGILAQQIFAELSAEEQQEVQKETQELLMELYEIEMAYTEEIYTS--IGL-VED 252 Query: 321 MKQYIEFVADRLMLELGFNKIFRVE--NPFDFMENISLEGKT-NFFEKRVGEYQRMGVMS 377 + +++ + A++ ++ LG F E NP + + + K +FF + Y + + Sbjct: 253 VNRFVRYNANKGLMNLGLEPKFEEEEINPI-VLNGLRTDTKNHDFFSVKGNGYVKATNVE 311 Query: 378 NSTENSFTLD 387 ++ F + Sbjct: 312 KLADDDFVFN 321 >1PIY-A nrPDB Length = 375 Score = 253 bits (646), Expect = 1e-67, Method: Composition-based stats. Identities = 74/335 (22%), Positives = 131/335 (39%), Gaps = 46/335 (13%) Query: 62 APTNPSVEDEPLLRENPRRFVVFPIEYHDIWQ-MYKKAEASFWTAEEVDLSKDIQHWEAL 120 + T EP+ P + + +DI++ + +K + FW EEVD+S+D ++AL Sbjct: 6 SQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQLSFFWRPEEVDVSRDRIDYQAL 65 Query: 121 KPDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLL 180 E+H L + D I + + + E + E IHS Y+ + Sbjct: 66 PEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISIPELETWVETWAFSETIHSRSYTHI 125 Query: 181 IDTYIKDPKEREYLFNAIETMPCVKKKADWALRWI-------------GDKEATYGERVV 227 I + DP +F+ I T ++K+A+ + G+ T + V Sbjct: 126 IRNIVNDPS---VVFDDIVTNEQIQKRAEGISSYYDELIEMTSYWHLLGEGTHTVNGKTV 182 Query: 228 AFA----------------AVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHC 271 + A+E I F SFA F +R LM G LI+RDE LH Sbjct: 183 TVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEALHL 242 Query: 272 DFACLMFKHL-----------VHKPAEQRVREIITNAVRIEQEFLTEAL-PVKLIGMNCT 319 M L + + +Q ++ A + E+++ +IG+N Sbjct: 243 TGTQHMLNLLRSGADDPEMAEIAEECKQECYDLFVQAAQQEKDWADYLFRDGSMIGLNKD 302 Query: 320 LMKQYIEFVADRLMLELGFNKIFRV-ENPFDFMEN 353 ++ QY+E++ + M +G + F NP ++ Sbjct: 303 ILCQYVEYITNIRMQAVGLDLPFNTRSNPIPWINT 337 >3N37-A nrPDB Length = 319 Score = 252 bits (643), Expect = 2e-67, Method: Composition-based stats. Identities = 54/304 (17%), Positives = 110/304 (36%), Gaps = 15/304 (4%) Query: 93 QMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQ 152 +++ + ++FW E+V LS DI W+ L E+ V D + N Sbjct: 21 EVWNRLTSNFWLPEKVPLSNDIPAWQTLTVVEQQLTMRVFTGLTLLDTLQNVIGAPSLMP 80 Query: 153 EVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWAL 212 + ME +H+ YS + T + K+ + + E +++KA Sbjct: 81 DALTPHEEAVLSNISFMEAVHARSYSSIFSTLCQT-KDVDAAYAWSEENAPLQRKAQIIQ 139 Query: 213 RWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCD 272 + + ++ +A +E F F + RG + LI RDE +H Sbjct: 140 QHYRGDDPL--KKKIASVFLESFLFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHGY 197 Query: 273 FACLMFKHLVHKPAEQRVREIITNAVRIEQEF------LTEALPVKLIGMNCTLMKQYIE 326 + ++ + K + + E+ + A + E T+ L + +K ++ Sbjct: 198 YIGYKYQKNMEKISLGQREELKSFAFDLLLELYDNELQYTDELYAETPW--ADDVKAFLC 255 Query: 327 FVADRLMLELGFNKIFRVE----NPFDFMENISLEGKTNFFEKRVGEYQRMGVMSNSTEN 382 + A++ ++ LG+ +F E NP + + F G MG + + Sbjct: 256 YNANKALMNLGYEPLFPAEMAEVNPAILAALSPNADENHDFFSGSGSSYVMGKAVETEDE 315 Query: 383 SFTL 386 + Sbjct: 316 DWNF 319 >3DHZ-A nrPDB Length = 329 Score = 250 bits (639), Expect = 7e-67, Method: Composition-based stats. Identities = 54/303 (17%), Positives = 112/303 (36%), Gaps = 13/303 (4%) Query: 93 QMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQ 152 +++ + +FW E++ +S DIQ W + P E+ V D I Sbjct: 31 EVWDRLTGNFWLPEKIPVSNDIQSWNKMTPQEQLATMRVFTGLTLLDTIQGTVGAISLLP 90 Query: 153 EVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWAL 212 + + Y ME++H++ YS + T P+ E F E +++KA + Sbjct: 91 DAETMHEEAVYTNIAFMESVHAKSYSNIFMTLASTPQINEA-FRWSEENENLQRKAKIIM 149 Query: 213 RWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCD 272 + + ++ VA +E F F +L R + LI RDE +H Sbjct: 150 SYYNGDDPL--KKKVASTLLESFLFYSGFYLPMYLSSRAKLTNTADIIRLIIRDESVHGY 207 Query: 273 FACLMFKHLVHKPAEQRVREIITNAVRIEQEFLTEALP-----VKLIGMNCTLMKQYIEF 327 + ++ V K +E E + + + +G +K+++ + Sbjct: 208 YIGYKYQQGVKKLSEAEQEEYKAYTFDLMYDLYENEIEYTEDIYDDLGW-TEDVKRFLRY 266 Query: 328 VADRLMLELGFNKIFRVE----NPFDFMENISLEGKTNFFEKRVGEYQRMGVMSNSTENS 383 A++ + LG+ +F + +P + + F G +G ++T++ Sbjct: 267 NANKALNNLGYEGLFPTDETKVSPAILSSLSPNADENHDFFSGSGSSYVIGKAEDTTDDD 326 Query: 384 FTL 386 + Sbjct: 327 WDF 329 >3MJO-A nrPDB Length = 296 Score = 248 bits (632), Expect = 4e-66, Method: Composition-based stats. Identities = 49/257 (19%), Positives = 97/257 (37%), Gaps = 9/257 (3%) Query: 93 QMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQ 152 +++ + +FW E++ +S DIQ W + P E+ V D I Sbjct: 30 EVWDRLTGNFWLPEKIPVSNDIQSWNKMTPQEQLATMRVFTGLTLLDTIQGTVGAISLLP 89 Query: 153 EVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWAL 212 + + Y ME++H++ YS + T P+ E F E +++KA + Sbjct: 90 DAETMHEEAVYTNIAFMESVHAKSYSNIFMTLASTPQINEA-FRWSEENENLQRKAKIIM 148 Query: 213 RWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCD 272 + + ++ VA +E F F +L R + LI RDE +H Sbjct: 149 SYYNGDDPL--KKKVASTLLESFLFYSGFYLPMYLSSRAKLTNTADIIRLIIRDESVHGY 206 Query: 273 FACLMFKHLVHKPAEQRVREIITNAVRIEQEFLTEALP-----VKLIGMNCTLMKQYIEF 327 + ++ V K +E E + + + +G +K+++ + Sbjct: 207 YIGYKYQQGVKKLSEAEQEEYKAYTFDLMYDLYENEIEYTEDIYDDLGW-TEDVKRFLRY 265 Query: 328 VADRLMLELGFNKIFRV 344 A++ + LG+ +F Sbjct: 266 NANKALNNLGYEGLFPT 282 >6GP2-A nrPDB Length = 345 Score = 245 bits (626), Expect = 2e-65, Method: Composition-based stats. Identities = 58/303 (19%), Positives = 115/303 (37%), Gaps = 13/303 (4%) Query: 93 QMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIV-NENLVERFS 151 +++ + +FW E++ +S D+ W L P+ + I+ D I V + Sbjct: 47 EVWNRITQNFWLPEKIPVSNDLTSWRTLTPEWQELITRTFTGLTLLDTIQATVGDVAQVP 106 Query: 152 QEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWA 211 + E + F M +H+ + + T + E I T ++ Sbjct: 107 NSLTDHEQVIYTNF-AFMVAVHARSFGSIFSTLCSSEQIEEAHEWVINTETLQERAKALI 165 Query: 212 LRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHC 271 ++ D + VA A + G G F F+L RG +P + LI RD+ +H Sbjct: 166 PYYVNDDPL---KSKVAAALMPGFLLYGGFYLPFYLSARGKLPNTSDIIRLILRDKVIHN 222 Query: 272 DFACLMFKHLVHKPAEQRVREIITNAVRIEQEFLT-EALPVKLIGMNCTLMKQYIEF--- 327 ++ ++ V K + ++ E+ ++ E + E +K + + L I F Sbjct: 223 YYSGYKYQKKVAKLSPEKQAEMKEFVFKLLYELIDLEKAYLKELYEDFGLADDAIRFSVY 282 Query: 328 VADRLMLELGFNKIFRVE----NPFDFMENISLEGKTNFFEKRVGEYQRMGVMSNSTENS 383 A + + LG++ F E P F + + + + F G MGV + ++ Sbjct: 283 NAGKFLQNLGYDSPFTEEETRIEPEIFTQLSARADENHDFFSGNGSSYIMGVSEETEDDD 342 Query: 384 FTL 386 + Sbjct: 343 WEF 345 >1UZR-A nrPDB Length = 296 Score = 238 bits (606), Expect = 4e-63, Method: Composition-based stats. Identities = 48/256 (18%), Positives = 93/256 (36%), Gaps = 9/256 (3%) Query: 93 QMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQ 152 +++ + +FW E+V +S DI W L E+ V D I Sbjct: 26 EVWDRLTGNFWLPEKVPVSNDIPSWGTLTAGEKQLTMRVFTGLTMLDTIQGTVGAVSLIP 85 Query: 153 EVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWAL 212 + ME++H++ YS + T E + F E +++KA+ L Sbjct: 86 DALTPHEEAVLTNIAFMESVHAKSYSQIFSTLCSTA-EIDDAFRWSEENRNLQRKAEIVL 144 Query: 213 RWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCD 272 + E +R VA +E F F + R + LI RDE +H Sbjct: 145 QSYRGDEPL--KRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTADMIRLIIRDEAVHGY 202 Query: 273 FACLMFKHLVHKPAEQRVREIITNAVRIEQEFLTEALP-----VKLIGMNCTLMKQYIEF 327 + F+ + + E+ + E + +G+ +K+++ + Sbjct: 203 YIGYKFQRGLALVDDVTRAELKDYTYELLFELYDNEVEYTQDLYDEVGL-TEDVKKFLRY 261 Query: 328 VADRLMLELGFNKIFR 343 A++ ++ LG+ +F Sbjct: 262 NANKALMNLGYEALFP 277 >6EBP-A nrPDB Length = 355 Score = 233 bits (594), Expect = 9e-62, Method: Composition-based stats. Identities = 54/293 (18%), Positives = 108/293 (36%), Gaps = 23/293 (7%) Query: 93 QMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNE-NLVERFS 151 +++ + +FW E + +S D+ W L D + I+ D + + V + Sbjct: 57 EVWNRVTQNFWLPENIPVSNDLPSWNELDDDWQQLITRTFTGLTLLDTVQSSIGDVAQIK 116 Query: 152 QEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWA 211 + E + F M +H+ + + T + E ++ + Sbjct: 117 NSLTEQEQVIYANF-AFMVGVHARSFGTIFSTLCTSEQIEEAHEWVVDNEALQARPKALI 175 Query: 212 LRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHC 271 + D + +A A + G G F F+L RG +P + LI RD+ +H Sbjct: 176 PFYTADDPL---KSKIAAALMPGFLLYGGFYLPFYLSARGKLPNTSDIIRLILRDKVIHN 232 Query: 272 DFACLMFKHLVHKPAEQRVREIITNAVRIEQEFLTEALPVKLIGMNCTLMKQ-YIEF-VA 329 ++ ++ V K + ++ E+ + K+IG+ T + Q Y F +A Sbjct: 233 FYSGYKYQLKVAKLSPEKQAEMKQFVFDLL---------DKMIGLEKTYLHQLYDGFGLA 283 Query: 330 DRLMLELGFNKIFRVENPFDFMENISLEGKTNFFEKRVGEYQRMGVMSNSTEN 382 D + F + N F++N+ E E R+ + + + EN Sbjct: 284 DEAIR-------FSLYNAGKFLQNLGYESPFTKEETRIAPEVFAQLSARADEN 329 >4AC8-A nrPDB Length = 323 Score = 165 bits (418), Expect = 3e-41, Method: Composition-based stats. Identities = 62/269 (23%), Positives = 108/269 (40%), Gaps = 39/269 (14%) Query: 93 QMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQ 152 +++ A FW ++D ++D WE L DER + + + F A + V E+ ++ F Sbjct: 31 KLFAGGNAKFWHPADIDFTRDRADWEKLSDDERDYATRLCTQFIAGEEAVTED-IQPFMS 89 Query: 153 EVQVTEARC---FYGFQIAMENI-HSEMYSLLIDT---------YIKDPKEREYLFNAIE 199 ++ E R Y Q A E H++++ + +D Y+ D +F A E Sbjct: 90 AMRA-EGRLADEMYLTQFAFEEAKHTQVFRMWLDAVGISEDLHRYLDDLPAYRQIFYA-E 147 Query: 200 TMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLK---KRGLMPGL 256 C+ AL A V VEG+ + + W K +R ++PG+ Sbjct: 148 LPECLN-----ALSADPSPAAQVRASVTYNHIVEGMLALTGYYA--WHKICVERAILPGM 200 Query: 257 TFSNELISRDEGLH---CDFACLMFKHLVHKPA-----EQRVREIITNAVRIEQEFLTEA 308 I DE H F C +H+ A E R+ E+I A+R+ +E A Sbjct: 201 QELVRRIGDDERRHMAWGTFTCR--RHVAADDANWTVFETRMNELIPLALRLIEEGF--A 256 Query: 309 LPVKLIGMNCTLMKQYIEFVADRLMLELG 337 L + + ++++ D+ M G Sbjct: 257 LYGDQPPFDLSK-DDFLQYSTDKGMRRFG 284 >6QRZ-A nrPDB Length = 328 Score = 152 bits (383), Expect = 3e-37, Method: Composition-based stats. Identities = 55/218 (25%), Positives = 93/218 (42%), Gaps = 21/218 (9%) Query: 93 QMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQ 152 ++Y+ + FW ++D SKD + W+ L DE++++ ++++ F A + V ++ S Sbjct: 47 KLYQIGKRLFWDPAKIDFSKDKEDWKKLSKDEKNYLLNIVSLFMAGEEAVAVDITPLIS- 105 Query: 153 EVQVTEAR---CFYGFQIAMENI-HSEMYSLLIDTY-IKD-----PKEREYLFNAI--ET 200 + E R Y Q A E H+E + D+ I D E + I E Sbjct: 106 -TMINEGRVEDVIYLEQFAFEEAKHAEAFRRFCDSLEINDDLTIFTTEYNPWYQKIFYEE 164 Query: 201 MPCV--KKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTF 258 +P V K + D + + TY V AA G +F IF +MPGL+ Sbjct: 165 LPSVMWKLRVDPSPENLAVAVTTYNLYVEGVAAESG---YKTFKHIF--NSLNIMPGLSK 219 Query: 259 SNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITN 296 + LI+ DE H + + L+ + E R+ I Sbjct: 220 TVNLIATDESRHIAYGTYLITRLIVENGESIYRKAIEQ 257 >5OMK-A nrPDB Length = 316 Score = 94.8 bits (234), Expect = 5e-20, Method: Composition-based stats. Identities = 44/217 (20%), Positives = 83/217 (38%), Gaps = 8/217 (3%) Query: 89 HDIWQMYKKAEAS-FWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLV 147 H ++++Y+KA+ + W ++D S+D + + +L +E+ ++A F+A + V +++ Sbjct: 32 HPMFKLYEKAKRNGKWNPADIDFSQDQKDFASLTSEEKISALPLVAGFSAGEEAVTLDIL 91 Query: 148 ERFSQEVQVTEARCFYGFQIAM--ENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVK 205 + M E H EM+S + N + Sbjct: 92 PMAHALARQGRLEDVLFLTTFMHDEAKHVEMFSRWQQAVGIGQMDLSVFHNDHYKRIFYE 151 Query: 206 KKADWALRWIGD--KEATYGERVVAFAAVEGIFFSGSFASIFW-LKKRGLMPGLTFSNEL 262 + R D EA V VEG + + KK GL PGL + Sbjct: 152 ALPEAMNRLYADDSPEAVIRAATVYNMIVEGTLAESGYYTFRQIYKKAGLFPGLLQGIDY 211 Query: 263 ISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVR 299 ++ DEG H F + +V++ +R E+ + Sbjct: 212 LNMDEGRHIQFGIYTIQRIVNED--ERYYELFIRYMD 246 >5OLK-A nrPDB Length = 430 Score = 92.1 bits (227), Expect = 4e-19, Method: Composition-based stats. Identities = 64/393 (16%), Positives = 149/393 (37%), Gaps = 32/393 (8%) Query: 13 DQQQLQLSPLKRLTLADKENTPPTLSSTR----VLASKAARRIFQDSAELESKAPTNPSV 68 +L + L +KE + + ++ K F D A+ ++ Sbjct: 44 QDAKLISMQVYESLLNNKEQESEYIPTVEQVQDMVEDKLMSSEFHDVAKAYIIYRNKRAL 103 Query: 69 EDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEA-LKPDERHF 127 E + + E +R + P EY ++ + S+W E + + DIQ ++ L ER Sbjct: 104 ERKTNIFE--KRINLKPYEYPELNEYVAAIRHSYWIHTEFNFTSDIQDFKTGLSEVERSA 161 Query: 128 ISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKD 187 I + + + + V + + E E H + YS L++ + Sbjct: 162 IKNTMLAISQIEVAVKTFWGD-VHHRLPKPEIAAVGATFAESEVRHHDAYSHLLEILGLN 220 Query: 188 PKEREYLFNAIETMPCVKKKADWALRWI----GDKEATYGERVVAFA-AVEGIFFSGSFA 242 + F ++ P + K+ + + D + Y E ++ FA +E + F Sbjct: 221 EE-----FKELKKKPVIMKRVHYLETSLKHAKSDDDREYTESILLFALFIEHVSLFSQFL 275 Query: 243 SIFWLKK-RGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAE-------QRVREII 294 I K + ++ G++ + E S++E +H DF + + + E ++E+ Sbjct: 276 IIMAFNKHKNMLKGISNAVEATSKEEQIHGDFGVDIINIIKKENPEWFDEEHNNLIKEMC 335 Query: 295 TNAVRIEQEFLTEALPVKLIG-MNCTLMKQYIEFVADRLMLELGFNKIFRVENPF----D 349 N+ E + + + + ++ ++++ ++ + +G K+F ++ + Sbjct: 336 LNSFEAESKVVDWIFEKGELDFLPKAVINEFLKNRFNKSLEAIGLEKLFDIDEALLQETE 395 Query: 350 FMENISLEGKT-NFFEKRVGEYQRMGVMSNSTE 381 + ++ + K +FF KR Y + S + Sbjct: 396 WFDDEIIGTKHGDFFVKRSINYSKRTQSITSDD 428 >6CWO-A nrPDB Length = 344 Score = 90.6 bits (223), Expect = 9e-19, Method: Composition-based stats. Identities = 55/314 (17%), Positives = 115/314 (36%), Gaps = 26/314 (8%) Query: 79 RRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEA-LKPDERHFISHVLAFFAA 137 +R P EY ++ Q + ++W EVD + D Q + A L E+ + + L A Sbjct: 26 KRVNYKPFEYPEVLQFTEAINKAYWVHTEVDFTADTQDFHAHLSLAEKTAVKNSLLAIAQ 85 Query: 138 SDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNA 197 + V ++ + E E HSE YS L++ F Sbjct: 86 IEVAV-KSFWGNIYEHFPKPEFNGLGSTFAECEFRHSEAYSRLLEVLG-----YNDEFEK 139 Query: 198 IETMPCVKKKADWALRWIGDKEATYGERVVAFAAV-----EGIFFSGSFASIFWLKK-RG 251 + +P ++++ D+ + D ++ + + + E + FA + + +G Sbjct: 140 LLDVPVIRRRVDYLSNVLKDTKSQDNRKYMVSLILFSILIENVSLFSQFAILLSFTRFKG 199 Query: 252 LMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAE-------QRVREIITNAVRIEQEF 304 M ++ S DE +H + + + + + VRE + +++ +E + Sbjct: 200 YMKNVSNIIAWTSIDEQIHANGGIYIINKIREEFPDYFDEETLALVRETVKDSIAVESDI 259 Query: 305 LTEALPVKLI-GMNCTLMKQYIEFVADRLMLELGFNKIF----RVENPFDFM-ENISLEG 358 L I + + +++F D + ++ IF + E + Sbjct: 260 LDWIFEEGEIESIKKGDLVNFMKFRIDESLKQINIPVIFDVKVEDYKALAWFEEEVFANS 319 Query: 359 KTNFFEKRVGEYQR 372 +FF KR EY + Sbjct: 320 LDDFFAKRPVEYTK 333 >6CWP-A nrPDB Length = 307 Score = 84.4 bits (207), Expect = 7e-17, Method: Composition-based stats. Identities = 49/282 (17%), Positives = 106/282 (37%), Gaps = 21/282 (7%) Query: 79 RRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEA-LKPDERHFISHVLAFFAA 137 +R P EY ++ Q + ++W EVD + D Q + A L E+ + + L A Sbjct: 13 KRVNYKPFEYPEVLQFTEAINKAYWVHTEVDFTADTQDFHAHLSLAEKTAVKNSLLAIAQ 72 Query: 138 SDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNA 197 + V ++ + E E HSE YS L++ F Sbjct: 73 IEVAV-KSFWGNIYEHFPKPEFNGLGSTFAECEFRHSEAYSRLLEVLG-----YNDEFEK 126 Query: 198 IETMPCVKKKADWALRWIGDKEATYGERVVAFAAV-----EGIFFSGSFASIFWLKK-RG 251 + +P ++++ D+ + D ++ + + + E + FA + + +G Sbjct: 127 LLDVPVIRRRVDYLSNVLKDTKSQDNRKYMVSLILFSILIENVSLFSQFAILLSFTRFKG 186 Query: 252 LMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAE-------QRVREIITNAVRIEQEF 304 M ++ S DE +H + + + + + VRE + +++ +E + Sbjct: 187 YMKNVSNIIAWTSIDEQIHANGGIYIINKIREEFPDYFDEETLALVRETVKDSIAVESDI 246 Query: 305 LTEALPVKLI-GMNCTLMKQYIEFVADRLMLELGFNKIFRVE 345 L I + + +++F D + ++ IF V+ Sbjct: 247 LDWIFEEGEIESIKKGDLVNFMKFRIDESLKQINIPVIFDVK 288 >3N1X-A nrPDB Length = 498 Score = 39.4 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 38/238 (15%), Positives = 75/238 (31%), Gaps = 26/238 (10%) Query: 134 FFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREY 193 A + R ++ + R F + EN H ++ +K ++ ++ Sbjct: 98 GAIALEEYAASTAEARMARFAKAPGNRNMATFGMMDENRHGQIQLYFPYANVKRSRKWDW 157 Query: 194 LFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWL-----K 248 AI T A A R D + VA + + F F ++ +L Sbjct: 158 AHKAIHTNEW----AAIAARSFFDDMMMTRDS-VAVSIMLTFAFETGFCNMQFLGLAADA 212 Query: 249 KRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRI-------- 300 I DE H K LV + ++++ A+ Sbjct: 213 AEAGDHTFASLISSIQTDESRHAQQGGPSLKILVENGKKDEAQQMVDVAIWRSWKLFSVL 272 Query: 301 ---EQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENIS 355 ++ T M ++I +R +L+LG +K + + FM+++ Sbjct: 273 TGPIMDYYTPLESRNQSF--KEFMLEWIVAQFERQLLDLGLDKPWYWD---QFMQDLD 325 >3Q3N-A nrPDB Length = 500 Score = 36.3 bits (82), Expect = 0.023, Method: Composition-based stats. Identities = 56/329 (17%), Positives = 106/329 (32%), Gaps = 47/329 (14%) Query: 47 AARRIFQDSAELESKAPTNPS-VEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTA 105 A +D EL PS V +E L E + P+E W+ Y + + + Sbjct: 1 MAMHPRKDWYELTRATNWTPSYVTEEQLFPERMSGHMGIPLEK---WESYDEPYKTSY-P 56 Query: 106 EEVDLSKDIQH--------------WEALKPDERHFISHVLAFFAASD--GIVNENLVER 149 E V + ++ +E P + A + + E + R Sbjct: 57 EYVSIQREKDAGAYSVKAALERAKIYENSDPGWISTLKSHYGAIAVGEYAAVTGEGRMAR 116 Query: 150 FSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKAD 209 FS+ R F + E H ++ Y K ++ ++ + A + A Sbjct: 117 FSKA---PGNRNMATFGMMDELRHGQLQLFFPHEYCKKDRQFDWAWRAYHSNEW----AA 169 Query: 210 WALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWL-----KKRGLMPGLTFSNELIS 264 A + D T G ++ A + F F ++ +L I Sbjct: 170 IAAKHFFDDIIT-GRDAISVAIMLTFSFETGFTNMQFLGLAADAAEAGDYTFANLISSIQ 228 Query: 265 RDEGLHCDFACLMFKHLVH----KPAEQRVREIITNAVRI-------EQEFLTEALPVKL 313 DE H + L+ + A+++V I A R+ ++ T Sbjct: 229 TDESRHAQQGGPALQLLIENGKREEAQKKVDMAIWRAWRLFAVLTGPVMDYYTPLEDRSQ 288 Query: 314 IGMNCTLMKQYIEFVADRLMLELGFNKIF 342 M ++I +R +++LG +K + Sbjct: 289 SF--KEFMYEWIIGQFERSLIDLGLDKPW 315 >1ZA0-A nrPDB Length = 275 Score = 36.3 bits (82), Expect = 0.025, Method: Composition-based stats. Identities = 24/120 (20%), Positives = 41/120 (34%), Gaps = 17/120 (14%) Query: 162 FYGFQIAMENIHSEMYS-LLIDTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEA 220 + G A E++H+ L+ T DP E + + ++ ++ Sbjct: 99 WLGRWTAEEHLHAIALREYLVVTREVDPVANEDV------------RVQHVMKGYRAEKY 146 Query: 221 TYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKH 280 T E +V A E L + P L + I+RDE H +F + H Sbjct: 147 TQVETLVYMAFYE----RCGAVFCRNLAAQIEEPILAGLIDRIARDEVRHEEFFANLVTH 202 >5VQE-A nrPDB Length = 573 Score = 34.0 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 41/267 (15%), Positives = 83/267 (31%), Gaps = 35/267 (13%) Query: 104 TAEEVDLSKDIQHWEALKPDERHFISH---VLAFFA--ASDGIVNENLVERFSQEVQVTE 158 + D+ + L P E D V + ++++ E Sbjct: 305 LPTSIQNGADMLTF-TLNPTEDFKALQEGLSCGLLTHERLDEAVAR--ILGMKAKLRLPE 361 Query: 159 ARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDK 218 + AME I S+ + I D +P +K + Sbjct: 362 RKDVVPPLHAMERIQSKKHKKWALE-IADESITLVKDKQKGLLPLSPQKTKRIILVQATN 420 Query: 219 EATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMF 278 E G + +G+ F + W ++ PG +S E + RD L +A Sbjct: 421 EKPEGGYLSEARLFKGLLEKEGF-IVHWFEEVPR-PGTGYSIEDLKRDTDLFIYYANFKV 478 Query: 279 KHLVHKPAEQRVREII----------TNAVRIEQEFLTEALPVKLIGMNCTLMKQYIE-F 327 + Q ++ + FL+ + P L+ + ++K YI + Sbjct: 479 S------SNQTTIRLVWSDFLGDSSPKFVCDVPTLFLSFSNPYHLV--DVPMVKTYINAY 530 Query: 328 VADRLMLELGFNKI-----FRVENPFD 349 ++ + + K+ F+ ++P D Sbjct: 531 TSNEATVRMMIEKLMGRSSFKGKSPVD 557 >3CHI-A nrPDB Length = 336 Score = 33.6 bits (75), Expect = 0.16, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 40/111 (36%) Query: 252 LMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRIEQEFLTEALPV 311 + P + L RDE H + + L + EQ+ R ++ + F + L Sbjct: 212 IQPMHSLITTLHLRDETAHGSIVVEVVRELYARMNEQQRRALVRCLPIALEAFAEQDLSA 271 Query: 312 KLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISLEGKTNF 362 L+ +N ++ E V D G + +E + L+ +F Sbjct: 272 LLLELNAAGIRGAEEIVGDLRSTAGGTRLVRDFSGARKMVEQLGLDDAVDF 322 >5TW7-A nrPDB Length = 529 Score = 32.1 bits (71), Expect = 0.43, Method: Composition-based stats. Identities = 26/183 (14%), Positives = 55/183 (30%), Gaps = 14/183 (7%) Query: 137 ASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFN 196 DG + + FYG Q E H++ L++ ++ D + Sbjct: 148 LPDGFAVIGDTPSCPIAMMENTEKQFYGIQFHPEVTHTKQGRALLNRFVLDICGAQP--- 204 Query: 197 AIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGS----FASIFWLKKRGL 252 +++ +G E G ++V + +F Sbjct: 205 GWTMPNYIEEAVAKIREQVGSDEVILGLSGGVDSSVAAALIHRAIGDQLTCVFVDHGLLR 264 Query: 253 MPGLTFSNELISRD---EGLHCDFACLMFKHLVHKPAEQRVREII----TNAVRIEQEFL 305 + ++ +R+ + +H D L ++ R+II E++ L Sbjct: 265 LNEGKMVMDMFARNLGVKVIHVDAEGQFMAKLAGVTDPEKKRKIIGAEFIEVFDAEEKKL 324 Query: 306 TEA 308 T A Sbjct: 325 TNA 327 >5EUT-A nrPDB Length = 556 Score = 32.1 bits (71), Expect = 0.45, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 28/59 (47%), Gaps = 4/59 (6%) Query: 60 SKAPTNPSVEDEPLLRENP-RRFVVFPIEYHDIWQMYKKAEASFWTA-EEVDLSKDIQH 116 S T+ V EP+++ + FP+++ D W+ Y A W +V S++I+ Sbjct: 414 SSRDTDWVVVKEPVIKVAAIDNGLAFPLKHPDSWRAYPFYWA--WLPQAKVPFSQEIKD 470 >4HNE-A nrPDB Length = 384 Score = 31.7 bits (70), Expect = 0.53, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 28/59 (47%), Gaps = 4/59 (6%) Query: 60 SKAPTNPSVEDEPLLRENP-RRFVVFPIEYHDIWQMYKKAEASFWTA-EEVDLSKDIQH 116 S T+ V EP+++ + FP+++ D W+ Y A W +V S++I+ Sbjct: 257 SSRDTDWVVVKEPVIKVAAIDNGLAFPLKHPDSWRAYPFYWA--WLPQAKVPFSQEIKD 313 >5K52-A nrPDB Length = 265 Score = 31.7 bits (70), Expect = 0.57, Method: Composition-based stats. Identities = 35/224 (15%), Positives = 65/224 (29%), Gaps = 26/224 (11%) Query: 121 KPDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLL 180 + S + A + N V R ++ + E ME H + ++ Sbjct: 46 SETYKDAYSRINAIVIEGEDEAANNYV-RLAELM--PEQSEELASLAKMEARHKKGFTAC 102 Query: 181 IDTY--IKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFS 238 D + F+ + V A + ++ A+ Sbjct: 103 GKNLNVTPDMDFAKKFFSDLHGNFQVAAAAGNIV-----TCLLIQALIIEAFAISAYNVY 157 Query: 239 GSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFK---HLVHKPAEQRVREIIT 295 A F K E + +DE LH +F K E+ RE + Sbjct: 158 IPHADDFARK----------ITENVVKDEYLHLNFGEQWLKANFESAKDELERANRENLA 207 Query: 296 NAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFN 339 R+ E +AL ++GM + + + +GF+ Sbjct: 208 IVWRMLDEVAGDAL---VLGMEKEALMEDFTIAYQEALQNIGFS 248 >3ETC-A nrPDB Length = 580 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 9/37 (24%), Positives = 17/37 (45%) Query: 316 MNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFME 352 +N + +++EF +LM G + F +ME Sbjct: 353 LNPEVFNRFLEFTGIKLMEGFGQTETVVTIATFPWME 389 >2FNQ-A nrPDB Length = 699 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 19/124 (15%), Positives = 46/124 (37%), Gaps = 19/124 (15%) Query: 239 GSFAS--IFWLKKRGLMPGLTF-------SNELISRDEGLHCDFACLMFKHLVHKPAEQR 289 G + S W R ++ T + +D L A L F + +EQR Sbjct: 79 GGYWSGDPDWFVNRVIIISSTQDRVYSFPCFRWVIKDMVLFPGEATLPFNEVPAIVSEQR 138 Query: 290 VREIITNAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADR----------LMLELGFN 339 +E+ + + +++++ +P + + + ++F ++ ++ LG Sbjct: 139 QKELEQRKLTYQWDYVSDDMPGNIKAKTHDDLPRDVQFTDEKSRSYQESRKAALVNLGIG 198 Query: 340 KIFR 343 +F Sbjct: 199 SLFT 202 >1GPM-A nrPDB Length = 525 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 14/85 (16%), Positives = 30/85 (35%), Gaps = 3/85 (3%) Query: 153 EVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWAL 212 + E + FYG Q E H+ +++ +++D + E L + Sbjct: 166 AIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEAL---WTPAKIIDDAVARIR 222 Query: 213 RWIGDKEATYGERVVAFAAVEGIFF 237 +GD + G ++V + Sbjct: 223 EQVGDDKVILGLSGGVDSSVTAMLL 247 >3WCH-A nrPDB Length = 360 Score = 29.7 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 28/83 (33%), Gaps = 3/83 (3%) Query: 90 DIWQMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVER 149 ++W Y K F E +DL+ +Q L + H I V+ + + + Sbjct: 224 EVWSRYVKKLGDFALPENIDLA--VQCLNELITNALHHIPDVITYLSRLRN-QSVFNFCA 280 Query: 150 FSQEVQVTEARCFYGFQIAMENI 172 Q + + Y Q + Sbjct: 281 IPQVMAIATLAACYNNQQVFKGA 303 >6AH0-w nrPDB Length = 501 Score = 29.0 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 32/213 (15%), Positives = 70/213 (32%), Gaps = 21/213 (9%) Query: 8 LATIADQQQLQLSPLKRLTLADKENTPPTLSSTRVLASKAARRIFQDSAELESKAPTNPS 67 + TI +QQ+ +RL + S+ R + R +E Sbjct: 1 METILEQQRRYHEEKERLMDVMAKEMLTKKSTLRDQINSDHRTRAMQDRYMEVSGNLRDL 60 Query: 68 VEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFW-TAEEV--DLSKDIQHWEALKPDE 124 +D+ LR+ + P E+ + + K+ + E+ +S + + + + Sbjct: 61 YDDKDGLRKEELNAISGPNEFAEFYNRLKQIKEFHRKHPNEICVPMSVEFEELLKARENP 120 Query: 125 RHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTY 184 +++ F E + + + + + Y A E + Y + D Sbjct: 121 SEEAQNLVEF----------TDEEGYGRYLDLHDCYLKYINLKASEKLDYITYLSIFDQL 170 Query: 185 IKDPKEREYLFNAIETMPCVKKKADWALRWIGD 217 PKER+ K+ + L ++ D Sbjct: 171 FDIPKERK--------NAEYKRYLEMLLEYLQD 195 >5JRE-A nrPDB Length = 219 Score = 29.0 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 14/112 (12%), Positives = 41/112 (36%), Gaps = 16/112 (14%) Query: 235 IFFSGSFA---------SIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKP 285 +F+S F ++++ K +P D ++ + ++ K Sbjct: 105 MFYSNGFIGLQEYVEALALYYYIKENRIPSKEEL----GVDTWVYLFGIGDIAGEILRKS 160 Query: 286 AEQRVR---EIITNAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLML 334 +E+ ++ E A + + + L ++L + Y+ + ++L+ Sbjct: 161 SEELIKGNIEYAKKAKQDLESLYLDLLYIELKNFDLRRKLDYVSNIINKLIE 212 >5FIP-A nrPDB Length = 334 Score = 29.0 bits (63), Expect = 4.0, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 23/59 (38%), Gaps = 3/59 (5%) Query: 65 NPSVEDEPLLRENPRRFVVFPIEYH-DIWQMYKKAEASFWTAEEVDLSKDIQHWEALKP 122 NP + + F +Y D+ +Y+ A E D++ DI WE +K Sbjct: 107 NPGDPNAKIYSGAKEFFKEIASKYPNDLHIIYELANEPN--PTESDITNDIAGWEKVKK 163 >3DFA-A nrPDB Length = 286 Score = 28.6 bits (62), Expect = 5.2, Method: Composition-based stats. Identities = 6/22 (27%), Positives = 10/22 (45%) Query: 113 DIQHWEALKPDERHFISHVLAF 134 D+ W + D + I +L F Sbjct: 242 DLPQWRTISDDAKDLIRKMLTF 263 >5JD3-A nrPDB Length = 238 Score = 28.2 bits (61), Expect = 5.8, Method: Composition-based stats. Identities = 11/60 (18%), Positives = 22/60 (36%), Gaps = 9/60 (15%) Query: 241 FASIFWLKKRGLMPGLTFSNELISRDEGL--------HCD-FACLMFKHLVHKPAEQRVR 291 + + + + S RD+G+ H + L+ HL + E+R+R Sbjct: 18 YFQGMYFAAGSKLVIIGDSITDAGRDKGIGGEGLFNAHGSGYVALLNAHLFARFPERRLR 77 >3B55-A nrPDB Length = 451 Score = 27.8 bits (60), Expect = 7.7, Method: Composition-based stats. Identities = 6/34 (17%), Positives = 17/34 (50%), Gaps = 1/34 (2%) Query: 108 VDLSKDIQHWEALKPDERH-FISHVLAFFAASDG 140 + ++KD+ +E+L +E+ ++ A + Sbjct: 207 IPVTKDMNTFESLTKEEKEKYVLDAKTISALLEE 240 >3NCG-A nrPDB Length = 486 Score = 27.8 bits (60), Expect = 8.1, Method: Composition-based stats. Identities = 6/22 (27%), Positives = 10/22 (45%) Query: 113 DIQHWEALKPDERHFISHVLAF 134 D+ W + D + I +L F Sbjct: 242 DLPQWRTISDDAKDLIRKMLTF 263 >3UAN-A nrPDB Length = 269 Score = 27.4 bits (59), Expect = 9.6, Method: Composition-based stats. Identities = 9/45 (20%), Positives = 21/45 (46%), Gaps = 2/45 (4%) Query: 262 LISRD--EGLHCDFACLMFKHLVHKPAEQRVREIITNAVRIEQEF 304 LI RD E + D+ +++ HL + +++ R+ ++ Sbjct: 106 LILRDPSERVLSDYTQVLYNHLQKHKPYPPIEDLLMRDGRLNLDY 150 >4EP1-A nrPDB Length = 340 Score = 27.4 bits (59), Expect = 9.9, Method: Composition-based stats. Identities = 9/61 (14%), Positives = 27/61 (44%) Query: 282 VHKPAEQRVREIITNAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKI 341 + + ++ + +I A+ +++ L K++G+ + M++LG + + Sbjct: 41 LEELTQEEIISLIEFAIYLKKNKQEPLLQGKILGLIFDKHSTRTRVSFEAGMVQLGGHGM 100 Query: 342 F 342 F Sbjct: 101 F 101 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.126 0.311 Lambda K H 0.267 0.0384 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,600,424 Number of Sequences: 36641 Number of extensions: 454843 Number of successful extensions: 1456 Number of sequences better than 10.0: 51 Number of HSP's better than 10.0 without gapping: 60 Number of HSP's successfully gapped in prelim test: 26 Number of HSP's that attempted gapping in prelim test: 1303 Number of HSP's gapped (non-prelim): 92 length of query: 390 length of database: 10,336,785 effective HSP length: 99 effective length of query: 291 effective length of database: 6,709,326 effective search space: 1952413866 effective search space used: 1952413866 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 60 (27.8 bits)