BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P10635 (497 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3TBG-A nrPDB 922 0.0 2NNH-A nrPDB 366 e-101 4H1N-A nrPDB 360 e-99 3E6I-A nrPDB 343 8e-95 4GQS-A nrPDB 343 9e-95 1N6B-A nrPDB 342 2e-94 5W0C-A nrPDB 341 4e-94 5E0E-A nrPDB 338 4e-93 5E58-A nrPDB 332 2e-91 3DL9-A nrPDB 328 3e-90 3IBD-A nrPDB 327 6e-90 2PG7-A nrPDB 317 5e-87 6B82-A nrPDB 242 3e-64 6DWN-A nrPDB 240 1e-63 4R20-A nrPDB 236 2e-62 6IQ5-A nrPDB 232 2e-61 2HI4-A nrPDB 229 2e-60 4R1Z-A nrPDB 214 7e-56 5UYS-A nrPDB 196 2e-50 3QZ1-A nrPDB 189 2e-48 5VBU-A nrPDB 181 5e-46 5YLW-A nrPDB 138 6e-33 6DA2-A nrPDB 108 7e-24 5VEU-A nrPDB 101 7e-22 2VE3-A nrPDB 97 1e-20 3K9V-A nrPDB 91 1e-18 6C94-A nrPDB 90 2e-18 3EL3-A nrPDB 82 4e-16 3MDV-A nrPDB 81 8e-16 6AYB-A nrPDB 78 9e-15 4KPA-A nrPDB 69 3e-12 3S79-A nrPDB 68 1e-11 3MZS-A nrPDB 65 9e-11 5IT1-A nrPDB 62 4e-10 2W0A-A nrPDB 62 5e-10 3P3Z-A nrPDB 62 8e-10 2WX2-A nrPDB 60 2e-09 6M7L-A nrPDB 59 4e-09 4OQR-A nrPDB 59 6e-09 3N9Z-A nrPDB 58 8e-09 3ABA-A nrPDB 58 9e-09 3JUS-A nrPDB 58 1e-08 4OQS-A nrPDB 58 1e-08 5CJE-A nrPDB 57 1e-08 4ZGX-A nrPDB 57 1e-08 3L4D-A nrPDB 55 7e-08 6M7X-A nrPDB 54 1e-07 2X2N-A nrPDB 53 2e-07 4RM4-A nrPDB 53 3e-07 6GK6-A nrPDB 52 7e-07 2Z36-A nrPDB 50 2e-06 5YHJ-A nrPDB 50 2e-06 3ABB-A nrPDB 50 3e-06 3IVY-A nrPDB 50 3e-06 3R9C-A nrPDB 50 3e-06 2Y5N-A nrPDB 50 3e-06 6B11-A nrPDB 49 4e-06 5Z9I-A nrPDB 49 5e-06 1CPT-A nrPDB 49 5e-06 5LIE-A nrPDB 49 5e-06 5OFQ-A nrPDB 49 5e-06 5YSW-A nrPDB 49 6e-06 4WMZ-A nrPDB 49 6e-06 5JLC-A nrPDB 48 8e-06 5M0P-A nrPDB 48 8e-06 1Z8P-A nrPDB 48 1e-05 5FSA-A nrPDB 48 1e-05 5DQN-A nrPDB 47 2e-05 4YZR-A nrPDB 47 2e-05 6G71-A nrPDB 47 3e-05 5HIW-A nrPDB 46 3e-05 5Y1I-A nrPDB 46 3e-05 4YT3-A nrPDB 46 3e-05 2RFC-A nrPDB 46 3e-05 2X9P-A nrPDB 46 4e-05 1Q5D-A nrPDB 46 4e-05 2VZM-A nrPDB 46 5e-05 1WIY-A nrPDB 46 5e-05 3MGX-A nrPDB 45 5e-05 5LIV-A nrPDB 45 5e-05 6A7J-A nrPDB 45 5e-05 6FYJ-A nrPDB 45 6e-05 6F88-A nrPDB 45 6e-05 1EHE-A nrPDB 45 7e-05 6GMF-A nrPDB 45 8e-05 6CR2-A nrPDB 45 9e-05 2ZBZ-A nrPDB 45 9e-05 5D3U-A nrPDB 45 9e-05 1LG9-A nrPDB 44 1e-04 3TYW-A nrPDB 44 2e-04 3A50-A nrPDB 44 2e-04 4GGV-A nrPDB 44 2e-04 6A7I-A nrPDB 43 2e-04 5NWS-A nrPDB 43 4e-04 5XW2-A nrPDB 42 4e-04 5XNT-A nrPDB 42 5e-04 5VWS-A nrPDB 42 5e-04 6F0B-A nrPDB 42 5e-04 3AWQ-A nrPDB 42 5e-04 2IJ7-A nrPDB 42 5e-04 6GII-A nrPDB 42 6e-04 3EJB-B nrPDB 42 7e-04 2FR7-A nrPDB 42 7e-04 3TKT-A nrPDB 41 0.001 6FSH-A nrPDB 41 0.001 2WIO-A nrPDB 41 0.001 4TX3-A nrPDB 40 0.002 3A1L-A nrPDB 39 0.004 4Z5P-A nrPDB 39 0.007 4XE3-A nrPDB 39 0.007 5L94-A nrPDB 38 0.008 5EX6-C nrPDB 38 0.008 2NZA-A nrPDB 38 0.010 6CVC-A nrPDB 38 0.010 4WPZ-A nrPDB 38 0.011 6HQD-A nrPDB 38 0.011 5FYF-A nrPDB 38 0.011 4UBS-A nrPDB 38 0.012 1UED-A nrPDB 37 0.014 1ODO-A nrPDB 37 0.014 1UE8-A nrPDB 37 0.018 2WM5-A nrPDB 37 0.021 2XKR-A nrPDB 37 0.021 5HDI-A nrPDB 37 0.024 3WVS-A nrPDB 37 0.029 3RWL-A nrPDB 36 0.031 3OFT-A nrPDB 36 0.033 4PWV-A nrPDB 36 0.036 4JBT-A nrPDB 36 0.046 3NC3-A nrPDB 35 0.070 5DE9-A nrPDB 35 0.096 4MM0-A nrPDB 35 0.096 2UUQ-A nrPDB 35 0.11 1GWI-A nrPDB 35 0.11 5GWE-A nrPDB 34 0.12 3SN5-A nrPDB 34 0.12 5XJN-A nrPDB 34 0.14 2RCM-A nrPDB 34 0.15 5L1U-A nrPDB 33 0.19 6HQG-A nrPDB 33 0.22 4DO1-A nrPDB 33 0.29 2ZQJ-A nrPDB 33 0.36 5FOI-A nrPDB 32 0.45 4TRI-A nrPDB 32 0.46 1F4U-A nrPDB 32 0.52 5JRJ-A nrPDB 31 1.3 3OO3-A nrPDB 30 1.6 4Z5Q-A nrPDB 30 1.9 5Z7C-A nrPDB 30 2.0 5A01-A nrPDB 29 3.8 5OMS-A nrPDB 29 3.9 6HQW-A nrPDB 29 4.0 3BUJ-A nrPDB 29 4.0 3NV6-A nrPDB 29 4.1 4IV9-A nrPDB 29 5.8 >3TBG-A nrPDB Length = 479 Score = 922 bits (2383), Expect = 0.0, Method: Compositional matrix adjust. Identities = 450/450 (100%), Positives = 450/450 (100%) Query: 48 HVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPIT 107 HVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPIT Sbjct: 26 HVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPIT 85 Query: 108 QILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANH 167 QILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANH Sbjct: 86 QILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANH 145 Query: 168 SGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAV 227 SGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAV Sbjct: 146 SGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAV 205 Query: 228 PVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPE 287 PVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPE Sbjct: 206 PVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPE 265 Query: 288 SSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEM 347 SSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEM Sbjct: 266 SSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEM 325 Query: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA Sbjct: 326 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 385 Query: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS Sbjct: 386 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 445 Query: 468 VPTGQPRPSHHGVFAFLVSPSPYELCAVPR 497 VPTGQPRPSHHGVFAFLVSPSPYELCAVPR Sbjct: 446 VPTGQPRPSHHGVFAFLVSPSPYELCAVPR 475 >2NNH-A nrPDB Length = 476 Score = 366 bits (940), Expect = e-101, Method: Compositional matrix adjust. Identities = 199/476 (41%), Positives = 284/476 (59%), Gaps = 7/476 (1%) Query: 23 MHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLN 82 M ++ + PPGP PLP +GN+L +D ++ F + +G VF++ P+VV + Sbjct: 1 MAKKTSSKGKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFH 60 Query: 83 GLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNL 142 G AV+EAL+ +GE+ + R PI+Q + G G+ ++ G W+E RRFS++TLRN Sbjct: 61 GYEAVKEALIDNGEEFSGRGNSPISQRITKG---LGI-ISSNGKRWKEIRRFSLTTLRNF 116 Query: 143 GLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRF 202 G+GK+S+E V EEA CL P P +L A NVI S+ +RF+Y D F Sbjct: 117 GMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNF 176 Query: 203 LRLLDLAQEGLKEESGFLREVLNAVPVLLHI-PALAGKVLRFQKAFLTQLDELLTEHRMT 261 L L+ E + + +V N P+L+ P KVL+ + + E + EH+ + Sbjct: 177 LTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQAS 236 Query: 262 WDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLM 321 D PRD + FL +ME+ K N +S FN ENL VADLF AG TTSTTL +GLLL+ Sbjct: 237 LD-VNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLL 295 Query: 322 ILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRD 381 + HP+V +VQ+EID VIG+ R P M D++HMPYT AV+HE+QR+ D+VP GV H + D Sbjct: 296 LKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTD 355 Query: 382 IEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRR 441 + + + IPKGTT++ L+SVL D+ + P F P HFLD G+F K + F+PFSAG+R Sbjct: 356 TKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKR 415 Query: 442 ACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVS-PSPYELCAVP 496 C GE LARMELFLF T++LQ+F+ + V +VS P Y++C +P Sbjct: 416 ICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIP 471 >4H1N-A nrPDB Length = 479 Score = 360 bits (923), Expect = e-99, Method: Compositional matrix adjust. Identities = 195/448 (43%), Positives = 267/448 (59%), Gaps = 6/448 (1%) Query: 23 MHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLN 82 M ++ + PPGP PLP LGNLL +D + F +LR ++GDVF++ L PVVVL Sbjct: 1 MAKKTSSKGKLPPGPSPLPVLGNLLQMDRKGLLRSFLRLREKYGDVFTVYLGSRPVVVLC 60 Query: 83 GLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNL 142 G A+REALV E + R + + + G GV A G WR RRFS++T+R+ Sbjct: 61 GTDAIREALVDQAEAFSGRGKIAVVDPIFQG---YGVIFAN-GERWRALRRFSLATMRDF 116 Query: 143 GLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRF 202 G+GK+S+E+ + EEA CL G L SN+I S+ G+RF+Y DP F Sbjct: 117 GMGKRSVEERIQEEARCLVEELRKSKGALLDNTLLFHSITSNIICSIVFGKRFDYKDPVF 176 Query: 203 LRLLDLAQEGLKEESGFLREVLNAVPVLL-HIPALAGKVLRFQKAFLTQLDELLTEHRMT 261 LRLLDL + S F +V L + P ++ R + T + + + +HR T Sbjct: 177 LRLLDLFFQSFSLISSFSSQVFELFSGFLKYFPGTHRQIYRNLQEINTFIGQSVEKHRAT 236 Query: 262 WDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLM 321 DP+ P RD + +L MEK K +P S F+ +NL + V LF+AG TTSTTL +G LLM Sbjct: 237 LDPSNP-RDFIDVYLLRMEKDKSDPSSEFHHQNLILTVLSLFAAGTETTSTTLRYGFLLM 295 Query: 322 ILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRD 381 + +P V RVQ+EI+ VIG R P + D+A MPYT AVIHE+QR GD++P GV H ++D Sbjct: 296 LKYPHVTERVQKEIEQVIGSHRPPALDDRAKMPYTDAVIHEIQRLGDLIPFGVPHTVTKD 355 Query: 382 IEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRR 441 + +G+ IPK T + LSS L D +E P F+P HFLDA G + E F+PFS G+R Sbjct: 356 TQFRGYVIPKNTEVFPVLSSALHDPRYFETPNTFNPGHFLDANGALKRNEGFMPFSLGKR 415 Query: 442 ACLGEPLARMELFLFFTSLLQHFSFSVP 469 CLGE +AR ELFLFFT++LQ+FS + P Sbjct: 416 ICLGEGIARTELFLFFTTILQNFSIASP 443 >3E6I-A nrPDB Length = 476 Score = 343 bits (881), Expect = 8e-95, Method: Compositional matrix adjust. Identities = 190/481 (39%), Positives = 275/481 (57%), Gaps = 16/481 (3%) Query: 23 MHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLN 82 M ++ + PPGP PLP +GNL ++ +N P F +L +RFG VF+L + +VV++ Sbjct: 1 MAKKTSSKGKLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 60 Query: 83 GLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNL 142 G AV+EAL+ + ++ + R +P R +G+ GP W++ RRFS++TLRN Sbjct: 61 GYKAVKEALLDYKDEFSGRGDLPAFH----AHRDRGIIFNN-GPTWKDIRRFSLTTLRNY 115 Query: 143 GLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRF 202 G+GK+ E + EA L A G+PF P L+ A NVIA + + F+Y+D +F Sbjct: 116 GMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKF 175 Query: 203 LRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAGKVLRFQKAFLTQLDELLTEHRMT 261 LRL+ L E S ++ N P LH +P KV++ + E + EH + Sbjct: 176 LRLMYLFNENFHLLSTPWLQLYNNFPSFLHYLPGSHRKVIKNVAEVKEYVSERVKEHHQS 235 Query: 262 WDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLM 321 DP PRDLT+ L EMEK K + E + + + + VADLF AG TTSTTL +GLL++ Sbjct: 236 LDP-NCPRDLTDCLLVEMEKEKHSAERLYTMDGITVTVADLFFAGTETTSTTLRYGLLIL 294 Query: 322 ILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRD 381 + +P+++ ++ +EID VIG R P + D+ MPY AV+HE+QRF +VP + H +RD Sbjct: 295 MKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRD 354 Query: 382 IEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRR 441 +G+ IPKGT ++ L SVL D + P +F PEHFL+ G F + F PFS G+R Sbjct: 355 TIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFSTGKR 414 Query: 442 ACLGEPLARMELFLFFTSLLQHFSFSVPTGQPR-----PSHHGVFAFLVSPSPYELCAVP 496 C GE LARMELFL ++LQHF+ P P+ P H G F P Y+LC +P Sbjct: 415 VCAGEGLARMELFLLLCAILQHFNLK-PLVDPKDIDLSPIHIG---FGCIPPRYKLCVIP 470 Query: 497 R 497 R Sbjct: 471 R 471 >4GQS-A nrPDB Length = 477 Score = 343 bits (880), Expect = 9e-95, Method: Compositional matrix adjust. Identities = 190/468 (40%), Positives = 275/468 (58%), Gaps = 7/468 (1%) Query: 31 ARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREA 90 + PPGP PLP +GN+L +D ++ L + +G VF+L +VVL+G V+EA Sbjct: 10 GKLPPGPTPLPVIGNILQIDIKDVSKSLTNLSKIYGPVFTLYFGLERMVVLHGYEVVKEA 69 Query: 91 LVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLE 150 L+ GE+ + R P+ + R G+ + G W+E RRFS+ TLRN G+GK+S+E Sbjct: 70 LIDLGEEFSGRGHFPLAERAN---RGFGIVFSN-GKRWKEIRRFSLMTLRNFGMGKRSIE 125 Query: 151 QWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQ 210 V EEA CL P P +L A NVI S+ +RF+Y D +FL L++ Sbjct: 126 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQFLNLMEKLN 185 Query: 211 EGLKEESGFLREVLNAVPVLL-HIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPR 269 E ++ S ++ N P ++ + P K+L+ + + E + EH+ + D PR Sbjct: 186 ENIRIVSTPWIQICNNFPTIIDYFPGTHNKLLKNLAFMESDILEKVKEHQESMD-INNPR 244 Query: 270 DLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQR 329 D + FL +MEK K N +S F ENL I ADL AG TTSTTL + LLL++ HP+V Sbjct: 245 DFIDCFLIKMEKEKQNQQSEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTA 304 Query: 330 RVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRI 389 +VQ+EI+ V+G+ R P M D+ HMPYT AV+HEVQR+ D++P + H + D++ + + I Sbjct: 305 KVQEEIERVVGRNRSPCMQDRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLI 364 Query: 390 PKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLA 449 PKGTT++T+L+SVL D + P F P HFLD G+F K F+PFSAG+R C+GE LA Sbjct: 365 PKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLA 424 Query: 450 RMELFLFFTSLLQHFSF-SVPTGQPRPSHHGVFAFLVSPSPYELCAVP 496 RMELFLF T +LQ+F+ S+ + + V F P Y+LC +P Sbjct: 425 RMELFLFLTFILQNFNLKSLIDPKDLDTTPVVNGFASVPPFYQLCFIP 472 >1N6B-A nrPDB Length = 473 Score = 342 bits (877), Expect = 2e-94, Method: Compositional matrix adjust. Identities = 198/477 (41%), Positives = 280/477 (58%), Gaps = 12/477 (2%) Query: 23 MHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLN 82 M ++ + PPGP P P +GN+L +D ++ + +G VF++ L P VVL+ Sbjct: 1 MAKKTSSKGKLPPGPTPFPIIGNILQIDAKDISKSLTKFSECYGPVFTVYLGMKPTVVLH 60 Query: 83 GLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLA-RYGPAWREQRRFSVSTLRN 141 G AV+EALV GE+ A R VPI + + S+G+ +A W+E RRFS+ TLRN Sbjct: 61 GYEAVKEALVDLGEEFAGRGSVPILEKV-----SKGLGIAFSNAKTWKEMRRFSLMTLRN 115 Query: 142 LGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPR 201 G+GK+S+E + EEA CL + P P +L A NVI S+ RF+Y D Sbjct: 116 FGMGKRSIEDRIQEEARCLVEELRKTNASPCDPTFILGCAPCNVICSVIFHNRFDYKDEE 175 Query: 202 FLRLLDLAQEGLKEESGFLREVLNAVPVLL-HIPALAGKVLRFQKAFLTQLDELLTEHRM 260 FL+L++ E ++ +V N P LL + P + +L+ + E + EH+ Sbjct: 176 FLKLMESLHENVELLGTPWLQVYNNFPALLDYFPGIHKTLLKNADYIKNFIMEKVKEHQK 235 Query: 261 TWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLL 320 D PRD + FL +ME+ + N E F E+L I V+DLF AG TTSTTL + LLL Sbjct: 236 LLD-VNNPRDFIDCFLIKMEQ-ENNLE--FTLESLVIAVSDLFGAGTETTSTTLRYSLLL 291 Query: 321 MILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSR 380 ++ HP+V RVQ+EI+ VIG+ R P M D++ MPYT AVIHE+QRF D++P + H +R Sbjct: 292 LLKHPEVAARVQEEIERVIGRHRSPCMQDRSRMPYTDAVIHEIQRFIDLLPTNLPHAVTR 351 Query: 381 DIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGR 440 D+ + + IPKGT +IT+L+SVL DE + P F P HFLD G+F K + F+PFSAG+ Sbjct: 352 DVRFRNYFIPKGTDIITSLTSVLHDEKAFPNPKVFDPGHFLDESGNFKKSDYFMPFSAGK 411 Query: 441 RACLGEPLARMELFLFFTSLLQHFSF-SVPTGQPRPSHHGVFAFLVSPSPYELCAVP 496 R C+GE LARMELFLF TS+LQ+F S+ + V F+ P Y+LC +P Sbjct: 412 RMCVGEGLARMELFLFLTSILQNFKLQSLVEPKDLDITAVVNGFVSVPPSYQLCFIP 468 >5W0C-A nrPDB Length = 477 Score = 341 bits (875), Expect = 4e-94, Method: Compositional matrix adjust. Identities = 190/468 (40%), Positives = 276/468 (58%), Gaps = 7/468 (1%) Query: 31 ARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREA 90 + PPGP PLP +GN+L + ++ L + +G VF+L P+VVL+G AV+EA Sbjct: 10 GKLPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEA 69 Query: 91 LVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLE 150 L+ GE+ + R P+ + R G+ + G W+E RRFS+ TLRN G+GK+S+E Sbjct: 70 LIDLGEEFSGRGIFPLAERAN---RGFGIVFSN-GKKWKEIRRFSLMTLRNFGMGKRSIE 125 Query: 151 QWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQ 210 V EEA CL P P +L A NVI S+ +RF+Y D +FL L++ Sbjct: 126 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLN 185 Query: 211 EGLKE-ESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPR 269 E +K S +++ N P++ + P K+L+ + + E + EH+ + D P+ Sbjct: 186 ENIKILSSPWIQICNNFSPIIDYFPGTHNKLLKNVAFMKSYILEKVKEHQESMD-MNNPQ 244 Query: 270 DLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQR 329 D + FL +MEK K N S F E+L DLF AG TTSTTL + LLL++ HP+V Sbjct: 245 DFIDCFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTA 304 Query: 330 RVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRI 389 +VQ+EI+ VIG+ R P M D++HMPYT AV+HEVQR+ D++P + H + DI+ + + I Sbjct: 305 KVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLI 364 Query: 390 PKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLA 449 PKGTT++ +L+SVL D + P F P HFLD G+F K + F+PFSAG+R C+GE LA Sbjct: 365 PKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALA 424 Query: 450 RMELFLFFTSLLQHFSF-SVPTGQPRPSHHGVFAFLVSPSPYELCAVP 496 MELFLF TS+LQ+F+ S+ + + V F P Y+LC +P Sbjct: 425 GMELFLFLTSILQNFNLKSLVDPKNLDTTPVVNGFASVPPFYQLCFIP 472 >5E0E-A nrPDB Length = 463 Score = 338 bits (866), Expect = 4e-93, Method: Compositional matrix adjust. Identities = 188/460 (40%), Positives = 265/460 (57%), Gaps = 17/460 (3%) Query: 45 NLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPV 104 NLL +D F ++R ++GDVF++ L PVV+L G A+REALV E + R + Sbjct: 14 NLLQMDRGGFLNSFRRIREKYGDVFTVHLGPRPVVMLYGTEAIREALVDQAEAFSGRGTI 73 Query: 105 PITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAF 164 + + + R GV A G W+ RRFS+ T+R+ G+GK+S+E+ + EEA CL F Sbjct: 74 AVVEPIF---RGYGVVFAN-GERWKALRRFSLVTMRDFGMGKRSVEERIQEEARCLVEEF 129 Query: 165 ANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVL 224 G P P L +N+I S+ G RF+Y D +FLRLL L + S F +V Sbjct: 130 RKSQGAPLDPTFLFQCITANIICSIVFGERFDYKDHQFLRLLYLFYQSFSLISSFSSQVF 189 Query: 225 NAVPVLL-HIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAK 283 L + P ++ R + L + + + +HR T DP+ P RD + +L MEK K Sbjct: 190 ELFSGFLKYFPGTHRQISRNLQEILDYIGQSVEKHRATLDPSHP-RDFIDTYLLRMEKEK 248 Query: 284 GNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVR 343 N + F+ +NL I V LF AG T+STTL +G LLM+ +P V +VQ+EID VIG R Sbjct: 249 SNQHTEFDHQNLVISVLSLFFAGTETSSTTLRYGFLLMLKYPHVAEKVQKEIDQVIGSHR 308 Query: 344 RPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVL 403 P + D+ MPYT AVI+E+QRF D++P+GV H ++D +G+ +PK T + LSS L Sbjct: 309 LPTLEDRTKMPYTEAVIYEIQRFSDLIPIGVPHKVTKDTLFRGYLLPKNTEVYPILSSAL 368 Query: 404 KDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQH 463 D +E+P F+P+HFLDA G K EAF+PFS G+R CLGE +AR ELFLFFT++LQ+ Sbjct: 369 HDPQYFEQPDTFNPDHFLDANGALKKSEAFMPFSIGKRICLGEGIARNELFLFFTTILQN 428 Query: 464 FSFSVPTG------QPRPSHHGVFAFLVSPSPYELCAVPR 497 FS S P P+ S G P Y++C + R Sbjct: 429 FSLSSPVAPKDIDLSPKESGFGKV-----PQTYQICFLAR 463 >5E58-A nrPDB Length = 493 Score = 332 bits (851), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 177/425 (41%), Positives = 251/425 (59%), Gaps = 8/425 (1%) Query: 45 NLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPV 104 NLL +D F ++R ++GDVF++ L PVV+L G A+REALV E + R + Sbjct: 42 NLLQMDRGGFLNSFMRIREKYGDVFTVHLGPRPVVMLYGTEAIREALVDQAEAFSGRGTI 101 Query: 105 PITQ-ILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAA 163 + + ++G G+ + G W+ RRFS++T+R+ G+GK+S+E + EEA CL Sbjct: 102 AVIKPVIG----DYGMIFSN-GERWKVLRRFSLATMRDFGMGKRSVEDRIQEEAQCLVEE 156 Query: 164 FANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREV 223 G P P L +N+I S+ G R++Y D +FLRLLDL S F +V Sbjct: 157 LQKSQGAPLDPTFLFQCITANIICSIVFGERYDYKDRQFLRLLDLFYRTFSLMSSFSSQV 216 Query: 224 LNAVPVLL-HIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKA 282 + + P ++ R + L + + + +HR T DP+ P RD + +L MEK Sbjct: 217 FELFSGFMKYFPGAHRQITRNLQEILDYVGQSVEKHRATLDPSNP-RDFIDTYLLRMEKE 275 Query: 283 KGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342 K N + F+ +NL I V LF AG TTSTTL +G LLM+ +P V +VQ+EID VIG Sbjct: 276 KSNQHTEFHHQNLLISVLSLFFAGTETTSTTLRYGFLLMLKYPHVAEKVQKEIDQVIGSH 335 Query: 343 RRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSV 402 R P + D+ MPYT AVIHE+QRF D+ P+G H ++D +G+ +PK T + LSS Sbjct: 336 RLPTLEDRTKMPYTDAVIHEIQRFSDLAPIGAPHKVTKDTLFRGYLLPKNTEVYPILSSA 395 Query: 403 LKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQ 462 L D +E+P F+P+HFLDA G K EAF+PFS G+R CLGE +AR ELFLFFT++LQ Sbjct: 396 LHDPQYFEQPGTFNPDHFLDANGALKKSEAFMPFSIGKRICLGEGIARNELFLFFTTILQ 455 Query: 463 HFSFS 467 +FS S Sbjct: 456 NFSVS 460 >3DL9-A nrPDB Length = 479 Score = 328 bits (841), Expect = 3e-90, Method: Compositional matrix adjust. Identities = 180/438 (41%), Positives = 246/438 (56%), Gaps = 14/438 (3%) Query: 65 FGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARY 124 +G++FSL L VVLNG V+E LV E ADRP +P+ + + G+ +RY Sbjct: 47 YGEIFSLDLGGISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKM---TKMGGLLNSRY 103 Query: 125 GPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSN 184 G W + RR +V++ R G G+KS E + EE A + GRPF L+ AVSN Sbjct: 104 GRGWVDHRRLAVNSFRYFGYGQKSFESKILEETKFFNDAIETYKGRPFDFKQLITNAVSN 163 Query: 185 VIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQ 244 + + G RF Y+D F +++L E ++ + + NA P + +P + L Sbjct: 164 ITNLIIFGERFTYEDTDFQHMIELFSENVELAASASVFLYNAFPWIGILPFGKHQQLFRN 223 Query: 245 KAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFS 304 A + L E Q P+ +A+L EM++ K +P S+F+ ENL V +L Sbjct: 224 AAVVYDFLSRLIEKASVNRKPQLPQHFVDAYLDEMDQGKNDPSSTFSKENLIFSVGELII 283 Query: 305 AGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQ 364 AG TT+ L W +L M L+P++Q +VQ+EID ++G +P D+ MPYT AV+HEV Sbjct: 284 AGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCKMPYTEAVLHEVL 343 Query: 365 RFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQ 424 RF +IVPLG+ H TS D V+G+ IPKGTT+ITNL SV DE W P FHPE FLD+ Sbjct: 344 RFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFLDSS 403 Query: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS-----VPTGQPRPSHHG 479 G+F K EA +PFS GRR CLGE LARME+FLFFT+LLQ F VP +PR Sbjct: 404 GYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHFPHELVPDLKPR----- 458 Query: 480 VFAFLVSPSPYELCAVPR 497 + P PY +CA R Sbjct: 459 -LGMTLQPQPYLICAERR 475 >3IBD-A nrPDB Length = 476 Score = 327 bits (839), Expect = 6e-90, Method: Compositional matrix adjust. Identities = 177/428 (41%), Positives = 250/428 (58%), Gaps = 6/428 (1%) Query: 45 NLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPV 104 NLL +D + F + R ++GDVF++ L PVV+L G+ A+REALV E + R + Sbjct: 23 NLLQMDRRGLLKSFLRFREKYGDVFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKI 82 Query: 105 PITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAF 164 + R GV A G W+ RRFSV+T+R+ G+GK+S+E+ + EEA CL Sbjct: 83 AMVDPFF---RGYGVIFAN-GNRWKVLRRFSVTTMRDFGMGKRSVEERIQEEAQCLIEEL 138 Query: 165 ANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVL 224 G P L +N+I S+ G+RF Y D FL++L+L + S ++ Sbjct: 139 RKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLF 198 Query: 225 NAVPVLL-HIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAK 283 L H P +V + + + + +HR T DP+ PRDL + +L MEK K Sbjct: 199 ELFSGFLKHFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPS-APRDLIDTYLLHMEKEK 257 Query: 284 GNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVR 343 N S F+ +NL + LF AG TTSTTL +G LLM+ +P V RV +EI+ VIG R Sbjct: 258 SNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGPHR 317 Query: 344 RPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVL 403 PE+ D+A MPYT AVI+E+QRF D++P+GV H+ ++ +G+ IPK T + LS+ L Sbjct: 318 PPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILSTAL 377 Query: 404 KDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQH 463 D +EKP F+P+HFLDA G K EAF+PFS G+R CLGE +AR ELFLFFT++LQ+ Sbjct: 378 HDPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSLGKRICLGEGIARAELFLFFTTILQN 437 Query: 464 FSFSVPTG 471 FS + P Sbjct: 438 FSMASPVA 445 >2PG7-A nrPDB Length = 476 Score = 317 bits (813), Expect = 5e-87, Method: Compositional matrix adjust. Identities = 178/483 (36%), Positives = 272/483 (56%), Gaps = 19/483 (3%) Query: 23 MHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLN 82 M ++ + PPGP PLP +GN L ++ + ++ R+G VF++ L VVVL Sbjct: 1 MAKKTSSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 60 Query: 83 GLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNL 142 G AVREALV E+ + R + + GV + G ++ RRFS++TLR+ Sbjct: 61 GHDAVREALVDQAEEFSGRGE---QATFDWVFKGYGVVFSN-GERAKQLRRFSIATLRDF 116 Query: 143 GLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRF 202 G+GK+ +E+ + EEA L A G P L + VSNVI+S+ G RF+Y D F Sbjct: 117 GVGKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEF 176 Query: 203 LRLLDLAQ---EGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHR 259 L LL + + +G L E+ ++V + H+P + + + + + + ++ Sbjct: 177 LSLLRMMLGIFQFTSTSTGQLYEMFSSV--MKHLPGPQQQAFQLLQGLEDFIAKKVEHNQ 234 Query: 260 MTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLL 319 T DP PRD ++FL M++ + NP + F +NL + LF G T STTL +G L Sbjct: 235 RTLDP-NSPRDFIDSFLIRMQEEEKNPNTEFYLKNLVMTTLQLFVGGTETVSTTLRYGFL 293 Query: 320 LMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTS 379 L++ HP+V+ +V +EID VIG+ R+P+ D+A MPY AVIHE+QRFGD++P+ + Sbjct: 294 LLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVK 353 Query: 380 RDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAG 439 +D + + F +PKGT + L SVL+D + + P F+P+HFL+ +G F K +AF+PFS G Sbjct: 354 KDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIG 413 Query: 440 RRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPR-----PSHHGVFAFLVSPSPYELCA 494 +R C GE LARMELFLFFT+++Q+F + P+ P H G F P Y + Sbjct: 414 KRNCFGEGLARMELFLFFTTVMQNFRLK-SSQSPKDIDVSPKHVG---FATIPRNYTMSF 469 Query: 495 VPR 497 +PR Sbjct: 470 LPR 472 >6B82-A nrPDB Length = 509 Score = 242 bits (618), Expect = 3e-64, Method: Compositional matrix adjust. Identities = 148/480 (30%), Positives = 248/480 (51%), Gaps = 25/480 (5%) Query: 32 RYPPGPLPLPGLGNLLHVDFQNTPYCFDQ-LRRRFGDVFSLQLAWTPVVVLNGLAAVREA 90 R PP LP +G+L+ + + P+ F Q L++++GD++SL + ++++N +E Sbjct: 23 RSPPSLPSLPIIGSLMSLVSDSPPHIFFQDLQKKYGDLYSLMMGSHKLLIVNNHHHAKEI 82 Query: 91 LVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLE 150 L+ G+ A RP T +L + + A Y W+ R+ L G G S+E Sbjct: 83 LIKKGKIFAGRPRTVTTDLLTRDGKD--IAFADYSSTWKFHRKMVHGALCMFGEGSVSIE 140 Query: 151 QWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQ 210 + + EA+ +C L +AV+NV+ +L ++ D F +L +Q Sbjct: 141 KIICREASSMCEVLTESQNSAVDLGPELTRAVTNVVCALCFNSSYKRGDAEFESMLQYSQ 200 Query: 211 EGLKEESGFLREVL--NAVPVLLHIPALAGKVLRFQKAFLTQLDELLT----EHRMTW-D 263 G + V + V + + K LR + ++ D+LL EH++T+ D Sbjct: 201 -------GIVDTVAKDSLVDIFPWLQIFPNKDLRILRQCISIRDKLLQKKYEEHKVTYSD 253 Query: 264 PAQPPRDLTEAFLAEMEKAKGNPESS----FNDENLRIVVADLFSAGMVTTSTTLAWGLL 319 Q RDL +A L ++ N S+ ++++ + V ++F AG+ TT+TTL W + Sbjct: 254 NVQ--RDLLDALLRAKRSSENNNSSTRDVGLTEDHVLMTVGEIFGAGVETTTTTLKWSIA 311 Query: 320 LMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTS 379 ++ +P VQR++Q+E+D IG+ R P++ D+ ++PY A I EV R + PL + H+ Sbjct: 312 YLVHNPQVQRKIQEELDSKIGKERHPQLSDRGNLPYLEATICEVMRIRPVSPLLIPHVAL 371 Query: 380 RDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGH-FVKPE-AFLPFS 437 +D V + + KGT ++ N+ S+ DE W+ P F P FL+ +G P ++LPF Sbjct: 372 QDSSVGEYTVQKGTRVVINMWSLHHDEKEWKNPELFDPGRFLNEEGDGLCCPSGSYLPFG 431 Query: 438 AGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR 497 AG R CLGE LA+MELFLF +LQ F+ +PTGQP P G F ++ P +++ A R Sbjct: 432 AGVRVCLGEALAKMELFLFLAWILQRFTLEMPTGQPLPDLQGKFGVVLQPKKFKVVAKVR 491 >6DWN-A nrPDB Length = 491 Score = 240 bits (612), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 145/455 (31%), Positives = 242/455 (53%), Gaps = 22/455 (4%) Query: 32 RYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREAL 91 + PPGP P +G++L + +N ++ +++GDV +++ TPVVVL+GL +R+AL Sbjct: 11 KNPPGPWGWPLIGHMLTLG-KNPHLALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQAL 69 Query: 92 VTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKK---- 147 V G+D RP + ++ G F GP W +RR + + L++ + Sbjct: 70 VRQGDDFKGRPDLYTFTLISNGQSMS--FSPDSGPVWAARRRLAQNGLKSFSIASDPASS 127 Query: 148 ---SLEQWVTEEAACLCAAFANHSGRP--FRPNGLLDKAVSNVIASLTCGRRFEYDDPRF 202 LE+ V++EA L + P F P + +V+NVI ++ GRR++++ Sbjct: 128 TSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYDHNHQEL 187 Query: 203 LRLLDLAQE-GLKEESGFLREVLNAVPVLLHIPALAGKVLR-FQKAFLTQLDELLTEHRM 260 L L++L G SG + +P+L ++P + + + F + + +++ EH Sbjct: 188 LSLVNLNNNFGEVVGSG---NPADFIPILRYLPNPSLNAFKDLNEKFYSFMQKMVKEHYK 244 Query: 261 TWDPAQPPRDLTEAFLAEMEKAK--GNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGL 318 T++ RD+T++ + ++ + N +DE + +V DLF AG T +T ++W L Sbjct: 245 TFEKGHI-RDITDSLIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSL 303 Query: 319 LLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMT 378 + ++++P VQR++Q+E+D VIG+ RRP + D++H+PY A I E R VP + H T Sbjct: 304 MYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHST 363 Query: 379 SRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVK--PEAFLPF 436 +RD ++GF IPKG + N + D+ +W P F PE FL G K E + F Sbjct: 364 TRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIF 423 Query: 437 SAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTG 471 G+R C+GE +AR E+FLF LLQ FSVP G Sbjct: 424 GMGKRKCIGETIARWEVFLFLAILLQRVEFSVPLG 458 >4R20-A nrPDB Length = 486 Score = 236 bits (601), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 142/446 (31%), Positives = 226/446 (50%), Gaps = 17/446 (3%) Query: 58 FDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQ 117 F QL ++G +F L +V++ + VRE L+ G + A RP + T +L G + Sbjct: 45 FTQLSSQYGPLFGLYAGPHLTLVVSEIGLVREVLLQRGREFAGRPKMVTTDLLTQG--GK 102 Query: 118 GVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGL 177 + A Y P W+ RR S+ G G L+ V E A LC G+ + + Sbjct: 103 DIAFADYSPLWKNHRRLVHSSFTLFGEGSNKLQTIVQEAADSLCEELQACRGQSSDLSVV 162 Query: 178 LDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNA--VPVLLHIPA 235 L +AV+NVI L ++ DP Q ++ G ++ + V + + Sbjct: 163 LMRAVTNVICRLVFSSSYQPSDPEL-------QTVIQYNDGIVQTIARGGLVDIFPWLRI 215 Query: 236 LAGKVLRFQKAFLTQLDELLT----EHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFN 291 K L+ K ++ D+LL EH+ + P +P RDL +A L ++ G + Sbjct: 216 FPNKDLKRLKECVSIRDQLLYKKLLEHKKSLTPGEP-RDLLDALLIGQQRGSGGADD-IT 273 Query: 292 DENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQA 351 ++++ + A+ F AG+ TTSTTL W + ++ HP +Q RVQ E+D+ +G R P + D+ Sbjct: 274 EDHVLMTAAEAFGAGVETTSTTLLWTIAFLLHHPQLQERVQAELDECVGVDRPPCLSDRP 333 Query: 352 HMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEK 411 H+P AV+ EV R + P+ + H+ +D + G +PKGT ++ N+ ++ D W++ Sbjct: 334 HLPLLDAVLCEVMRIRPVSPILIPHVAMQDTSLGGHSVPKGTRVLVNMWAIHHDPKHWDQ 393 Query: 412 PFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTG 471 P +F+PE FL+ G +FLPF AG R C+GE LAR+ELFLF + LQ FSFS P+ Sbjct: 394 PEQFNPERFLEPSGKKKTQSSFLPFGAGPRVCVGESLARIELFLFVSRPLQRFSFSCPSE 453 Query: 472 QPRPSHHGVFAFLVSPSPYELCAVPR 497 P G F ++ P Y + PR Sbjct: 454 ASLPDLQGRFGVVLQPERYTVTVTPR 479 >6IQ5-A nrPDB Length = 463 Score = 232 bits (592), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 157/457 (34%), Positives = 225/457 (49%), Gaps = 24/457 (5%) Query: 58 FDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQ 117 F +L RR+GDVF ++L P+VVLNG A+ +ALV G ADRP +++ G RS Sbjct: 7 FARLARRYGDVFQIRLGSCPIVVLNGERAIHQALVQQGSAFADRPSFASFRVVS-GGRSM 65 Query: 118 GVFLARYGPAWREQRRFSVSTLRNLGL----GKKSLEQWVTEEAACLCAAFANHS--GRP 171 Y W+ QRR + S +RN ++ LE V EA L A S G Sbjct: 66 A--FGHYSEHWKVQRRAAHSMMRNFFTRQPRSRQVLEGHVLSEARELVALLVRGSADGAF 123 Query: 172 FRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQE-GLKEESGFLREVLNAVPVL 230 P L AV+NV++++ G R+ +DDP F LL +E G +G L +V+ P L Sbjct: 124 LDPRPLTVVAVANVMSAVCFGCRYSHDDPEFRELLSHNEEFGRTVGAGSLVDVM---PWL 180 Query: 231 LHIPALAGKVLR----FQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEK-AKGN 285 + P V R + F + + H + P PRD+ +AF+ EK A G+ Sbjct: 181 QYFPNPVRTVFREFEQLNRNFSNFILDKFLRHCESLRPGAAPRDMMDAFILSAEKKAAGD 240 Query: 286 PE---SSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342 + + EN+ + D+F A T ST L W LLL +PDVQ RVQ E+D V+G+ Sbjct: 241 SHGGGARLDLENVPATITDIFGASQDTLSTALQWLLLLFTRYPDVQTRVQAELDQVVGRD 300 Query: 343 RRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSV 402 R P MGDQ ++PY A ++E RF VP+ + H T+ + V G+ IPK T + N SV Sbjct: 301 RLPCMGDQPNLPYVLAFLYEAMRFSSFVPVTIPHATTANTSVLGYHIPKDTVVFVNQWSV 360 Query: 403 LKDEAVWEKPFRFHPEHFLDAQGHFVK--PEAFLPFSAGRRACLGEPLARMELFLFFTSL 460 D W P F P FLD G K + FS G+R C+GE L++M+LFLF + L Sbjct: 361 NHDPVKWPNPENFDPARFLDKDGLINKDLTSRVMIFSVGKRRCIGEELSKMQLFLFISIL 420 Query: 461 LQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR 497 F +P + + + P +++ R Sbjct: 421 AHQCDFRANPNEPAKMNFS-YGLTIKPKSFKVNVTLR 456 >2HI4-A nrPDB Length = 495 Score = 229 bits (584), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 148/456 (32%), Positives = 231/456 (50%), Gaps = 25/456 (5%) Query: 32 RYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREAL 91 + PP P P LG++L + +N ++ +R+GDV +++ TPV+VL+ L +R+AL Sbjct: 16 KSPPEPWGWPLLGHVLTLG-KNPHLALSRMSQRYGDVLQIRIGSTPVLVLSRLDTIRQAL 74 Query: 92 VTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKK---- 147 V G+D RP + + ++ G F GP W +RR + + L + Sbjct: 75 VRQGDDFKGRPDLYTSTLITDG--QSLTFSTDSGPVWAARRRLAQNALNTFSIASDPASS 132 Query: 148 ---SLEQWVTEEAACLCAAFANHSGRP--FRPNGLLDKAVSNVIASLTCGRRFEYDDPRF 202 LE+ V++EA L + P F P + +V+NVI ++ G+ F Sbjct: 133 SSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANVIGAMCFGQHFPESSDEM 192 Query: 203 LRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLR-FQKAFLTQLDELLTEHRMT 261 L L+ E ++ S L+ P+L ++P A + + F + FL L + + EH Sbjct: 193 LSLVKNTHEFVETASS--GNPLDFFPILRYLPNPALQRFKAFNQRFLWFLQKTVQEHYQD 250 Query: 262 WDPAQPPRDLTEAFLAEMEKAKGNPESSFN---DENLRIVVADLFSAGMVTTSTTLAWGL 318 +D RD+T A + +K P +S N E + +V D+F AG T +T ++W L Sbjct: 251 FD-KNSVRDITGALF---KHSKKGPRASGNLIPQEKIVNLVNDIFGAGFDTVTTAISWSL 306 Query: 319 LLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMT 378 + ++ P++QR++Q+E+D VIG+ RRP + D+ +PY A I E R +P + H T Sbjct: 307 MYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHSSFLPFTIPHST 366 Query: 379 SRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV-KP--EAFLP 435 +RD + GF IPK + N V D +WE P F PE FL A G + KP E + Sbjct: 367 TRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTAINKPLSEKMML 426 Query: 436 FSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTG 471 F G+R C+GE LA+ E+FLF LLQ FSVP G Sbjct: 427 FGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSVPPG 462 >4R1Z-A nrPDB Length = 439 Score = 214 bits (545), Expect = 7e-56, Method: Compositional matrix adjust. Identities = 132/433 (30%), Positives = 218/433 (50%), Gaps = 24/433 (5%) Query: 78 VVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVS 137 ++++N +E L+ G+ A RP T +L + + A Y W+ R+ Sbjct: 6 LLIVNNHHHAKEILIKKGKIFAGRPRTVTTDLLTRDGKD--IAFADYSSTWKFHRKMVHG 63 Query: 138 TLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEY 197 L G G S+E+ + EA+ +C L +AV+NV+ +L ++ Sbjct: 64 ALCMFGEGSVSIEKIICREASSMCEVLTESQNSAVDLGPELTRAVTNVVCALCFNSSYKR 123 Query: 198 DDPRFLRLLDLAQEGLKEESGFLREVL--NAVPVLLHIPALAGKVLRFQKAFLTQLDELL 255 D F +L +Q G + V + V + + K L + ++ D+LL Sbjct: 124 GDAEFESMLQYSQ-------GIVDTVAKDSLVDIFPWLQIFPNKDLTILRQCISIRDKLL 176 Query: 256 T----EHRMTW-DPAQPPRDLTEAFLAEMEKAKGNPESS----FNDENLRIVVADLFSAG 306 EH++T+ D Q RDL +A L ++ N S+ ++++ + V D+F AG Sbjct: 177 QKKYEEHKVTYSDNVQ--RDLLDALLRAKRSSENNNSSTRDVGLTEDHVLMTVGDIFGAG 234 Query: 307 MVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRF 366 + TT+T L W + ++ +P VQR++Q+E+D IG+ R P++ D+ ++PY A I EV R Sbjct: 235 VETTTTVLKWSIAYLVHNPQVQRKIQEELDSKIGKERHPQLSDRGNLPYLEATIREVLRI 294 Query: 367 GDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGH 426 + PL + H+ +D V + + KGT ++ NL S+ D+ W+ P F P FL+ +G Sbjct: 295 RPVSPLLIPHVALQDSSVGEYTVQKGTRVVINLWSLHHDKKEWKNPELFDPGRFLNEEGD 354 Query: 427 -FVKPE-AFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFL 484 P ++LPF AG R CLGE LA+MELFLF +LQ F+ +PTGQP P G F + Sbjct: 355 GLCCPSGSYLPFGAGVRVCLGEALAKMELFLFLAWILQRFTLEMPTGQPLPDLQGKFGVV 414 Query: 485 VSPSPYELCAVPR 497 + P +++ A R Sbjct: 415 LQPKKFKVVAKVR 427 >5UYS-A nrPDB Length = 494 Score = 196 bits (497), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 129/466 (27%), Positives = 228/466 (48%), Gaps = 19/466 (4%) Query: 27 QRWAARYPPGPLPLPGLGNL----LHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLN 82 ++ A+YP L LP +G+L H N F +L++++G ++S+++ V++ Sbjct: 3 KKTGAKYPKSLLSLPLVGSLPFLPRHGHMHNN---FFKLQKKYGPIYSVRMGTKTTVIVG 59 Query: 83 GLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNL 142 +E L+ G+D + RP + I +G+ A G W+ RR +++T Sbjct: 60 HHQLAKEVLIKKGKDFSGRPQMATLDIAS--NNRKGIAFADSGAHWQLHRRLAMATFALF 117 Query: 143 GLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRF 202 G + LE+ + +E + LC A H+G+ + + AV+NVI+ + ++ DP Sbjct: 118 KDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPE- 176 Query: 203 LRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQL-DELLTEHRMT 261 L ++ EG+ + +++ VP L P + L+ L +++L ++ Sbjct: 177 LNVIQNYNEGIIDNLS-KDSLVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEK 235 Query: 262 WDPAQPPRDLTEAFLAEMEKAKGN--PESS---FNDENLRIVVADLFSAGMVTTSTTLAW 316 + L A+M GN P+ +D ++ + D+F AG+ TT++ + W Sbjct: 236 FRSDSITNMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKW 295 Query: 317 GLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTH 376 L ++ +P V++++ +EID +G R P + D+ + A I EV R + P+ + H Sbjct: 296 TLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPH 355 Query: 377 MTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQG-HFVKPE-AFL 434 + D + F + KGT +I NL ++ +E W +P +F PE FL+ G + P ++L Sbjct: 356 KANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYL 415 Query: 435 PFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGV 480 PF AG R+C+GE LAR ELFL LLQ F VP PS G+ Sbjct: 416 PFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGI 461 >3QZ1-A nrPDB Length = 496 Score = 189 bits (480), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 140/462 (30%), Positives = 222/462 (48%), Gaps = 32/462 (6%) Query: 28 RWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAV 87 RW R P +PG LH+ N P L ++ G V+ L+L VVVLN + Sbjct: 22 RWKLRNLHLPPLVPGF---LHLLQPNLPIHLLSLTQKLGPVYRLRLGLQEVVVLNSKRTI 78 Query: 88 REALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKK 147 EA++ D A RP +P +++ R Q + L Y W+ ++ + S L L + Sbjct: 79 EEAMIRKWVDFAGRPQIPSYKLVS--QRCQDISLGDYSLLWKAHKKLTRSAL--LLGTRS 134 Query: 148 SLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLD 207 S+E WV + C +G P ++I LT G + +D D Sbjct: 135 SMEPWVDQLTQEFCERMRVQAGAPVTIQKEFSLLTCSIICYLTFGNK---EDTLVHAFHD 191 Query: 208 LAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQ---LDELLTEHRMTWDP 264 Q+ +K + ++L+ VP L P + R ++A + +++ L H+ + Sbjct: 192 CVQDLMKTWDHWSIQILDMVPFLRFFPNPG--LWRLKQAIENRDHMVEKQLRRHKESMVA 249 Query: 265 AQPPRDLTEAFLAEM--EKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMI 322 Q RD+T+ L + ++ + P + ++ + V DLF G TT++TL+W + ++ Sbjct: 250 GQW-RDMTDYMLQGVGRQRVEEGP-GQLLEGHVHMSVVDLFIGGTETTASTLSWAVAFLL 307 Query: 323 LHPDVQRRVQQEIDDVIG---QVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTS 379 HP++QRR+Q+E+D +G R D+A +P A I EV R +VPL + H T+ Sbjct: 308 HHPEIQRRLQEELDRELGPGASCSRVTYKDRARLPLLNATIAEVLRLRPVVPLALPHRTT 367 Query: 380 RDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAG 439 R + G+ IP+G +I NL DE VWE+P F P+ FL+ + P A L F G Sbjct: 368 RPSSIFGYDIPEGMVVIPNLQGAHLDETVWEQPHEFRPDRFLEPGAN---PSA-LAFGCG 423 Query: 440 RRACLGEPLARMELFLFFTSLLQHFSF------SVPTGQPRP 475 R CLGE LAR+ELF+ LLQ F+ ++P+ QP P Sbjct: 424 ARVCLGESLARLELFVVLARLLQAFTLLPPPVGALPSLQPDP 465 >5VBU-A nrPDB Length = 476 Score = 181 bits (460), Expect = 5e-46, Method: Compositional matrix adjust. Identities = 140/450 (31%), Positives = 214/450 (47%), Gaps = 37/450 (8%) Query: 41 PGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTAD 100 PG +LL D P L ++FG ++ L L VVVLN + EA+V D A Sbjct: 16 PGFLHLLQPDL---PIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAG 72 Query: 101 RPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACL 160 RP P+T L + L Y W+ ++ + S L LG+ + S+E V + Sbjct: 73 RPE-PLTYKL-VSRNYPDLSLGDYSLLWKAHKKLTRSALL-LGI-RDSMEPVVEQLTQEF 128 Query: 161 CAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDD--PRFLRLLDLAQEGLKEESG 218 C G P ++I LT G + + D+ P + + + QE LK S Sbjct: 129 CERMRAQPGTPVAIEEEFSLLTCSIICYLTFGDKIKDDNLMPAYYKCI---QEVLKTWSH 185 Query: 219 FLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDEL----LTEHRMTWDPAQPPRDLTEA 274 + ++++ +P L P LR K + + D + L +H+ + Q RD+ + Sbjct: 186 WSIQIVDVIPFLRFFP---NPGLRRLKQAIEKRDHIVEMQLRQHKESLVAGQW-RDMMDY 241 Query: 275 FLA-----EMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQR 329 L ME+ G + ++ + DL G TT+ TL+W ++ ++ HP++Q+ Sbjct: 242 MLQGVAQPSMEEGSGQ----LLEGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQ 297 Query: 330 RVQQEIDDVIG---QVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQG 386 R+Q+E+D +G R D+A +P A I EV R +VPL + H T+R + G Sbjct: 298 RLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISG 357 Query: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446 + IP+GT +I NL DE VWE+P F P+ FL+ K L F G R CLGE Sbjct: 358 YDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFLEPG----KNSRALAFGCGARVCLGE 413 Query: 447 PLARMELFLFFTSLLQHFSFSVPTGQPRPS 476 PLAR+ELF+ T LLQ F+ +P+G PS Sbjct: 414 PLARLELFVVLTRLLQAFTL-LPSGDALPS 442 >5YLW-A nrPDB Length = 495 Score = 138 bits (347), Expect = 6e-33, Method: Compositional matrix adjust. Identities = 125/495 (25%), Positives = 207/495 (41%), Gaps = 52/495 (10%) Query: 9 LAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDV 68 LA + I + L RR+R PPGP P P +GN+L + N F +L +R+G + Sbjct: 7 LAALFFIAATITFLSFRRRR---NLPPGPFPYPIVGNMLQLG-ANPHQVFAKLSKRYGPL 62 Query: 69 FSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAW 128 S+ L V+++ +E L HG+ + R S G FL W Sbjct: 63 MSIHLGSLYTVIVSSPEMAKEILHRHGQVFSGRTIAQAVHACDHDKISMG-FLP-VASEW 120 Query: 129 REQRR------FSVSTLR-NLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKA 181 R+ R+ FS ++ + GL ++ L+Q + C + SGR Sbjct: 121 RDMRKICKEQMFSNQSMEASQGLRRQKLQQLLDHVQKC------SDSGRAVDIREAAFIT 174 Query: 182 VSNVI-ASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGK- 239 N++ A+L + E+D + +E++ V ++ +P A Sbjct: 175 TLNLMSATLFSSQATEFDSKATME---------------FKEIIEGVATIVGVPNFADYF 219 Query: 240 -VLR-------------FQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGN 285 +LR F L +++ L E R+ A P + FL + Sbjct: 220 PILRPFDPQGVKRRADVFFGKLLAKIEGYLNE-RLESKRANPNAPKKDDFLEIVVDIIQA 278 Query: 286 PESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP 345 E + ++ DLF G T +T++ W + ++++PD R++ E+ V G + Sbjct: 279 NEFKLKTHHFTHLMLDLFVGGSDTNTTSIEWAMSELVMNPDKMARLKAELKSVAGDEKIV 338 Query: 346 EMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKD 405 + +PY AVI EV R PL + D EV G+ IPKGT ++ N ++ +D Sbjct: 339 DESAMPKLPYLQAVIKEVMRIHPPGPLLLPRKAESDQEVNGYLIPKGTQILINAYAIGRD 398 Query: 406 EAVWEKPFRFHPEHFLDAQGHFVKPE-AFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 ++W P F PE FLD + F + LPF +GRR C G PLA L + +L+ +F Sbjct: 399 PSIWTDPETFDPERFLDNKIDFKGQDYELLPFGSGRRVCPGMPLATRILHMATATLVHNF 458 Query: 465 SFSVPTGQPRPSHHG 479 + + + H Sbjct: 459 DWKLEDDSTAAADHA 473 >6DA2-A nrPDB Length = 487 Score = 108 bits (269), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 108/459 (23%), Positives = 182/459 (39%), Gaps = 57/459 (12%) Query: 35 PGPLPLPGLGNLLHVDFQNTPYC-FD-QLRRRFGDVFSLQLAWTPVVVLNGLAAVREALV 92 PGP PLP LGN+L + +C FD + +++G V+ PV+ + ++ LV Sbjct: 19 PGPTPLPFLGNILSY---HKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLV 75 Query: 93 THGED--TADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLE 150 T RP P+ G + +A W+ R T + L K + Sbjct: 76 KECYSVFTNRRPFGPV------GFMKSAISIAE-DEEWKRLRSLLSPTFTSGKL--KEMV 126 Query: 151 QWVTEEAACLCAAFANH--SGRPFRPNGLLDKAVSNVIASLTCG---------------- 192 + + L +G+P + +VI S + G Sbjct: 127 PIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVEN 186 Query: 193 ----RRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFL 248 RF++ DP FL + FL +L +L+I +V F + + Sbjct: 187 TKKLLRFDFLDPFFLSITVFP---------FLIPILE----VLNICVFPREVTNFLRKSV 233 Query: 249 TQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMV 308 ++ E E D + D + + + + +D L AG Sbjct: 234 KRMKESRLE-----DTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYE 288 Query: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGD 368 TTS+ L++ + + HPDVQ+++Q+EID V+ P M Y V++E R Sbjct: 289 TTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFP 348 Query: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428 I + + + +D+E+ G IPKG ++ ++ +D W +P +F PE F + Sbjct: 349 IA-MRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNI 407 Query: 429 KPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467 P + PF +G R C+G A M + L +LQ+FSF Sbjct: 408 DPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFK 446 >5VEU-A nrPDB Length = 480 Score = 101 bits (252), Expect = 7e-22, Method: Compositional matrix adjust. Identities = 110/462 (23%), Positives = 179/462 (38%), Gaps = 64/462 (13%) Query: 35 PGPLPLPGLGNLLHVDFQNTPYCFD-QLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93 PGP PLP LGN+L ++ + FD + +++G ++ PV+ + +R LV Sbjct: 18 PGPTPLPLLGNVL--SYRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVK 75 Query: 94 HGED--TADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151 T R P+ G + LA W+ R T + L K + Sbjct: 76 ECYSVFTNRRSLGPV------GFMKSAISLAE-DEEWKRIRSLLSPTFTSGKL--KEMFP 126 Query: 152 WVTEEAACLCAAFANHS--GRPFRPNGLLDKAVSNVIASLTCG----------------- 192 + + L + G+P + +VI + G Sbjct: 127 IIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQDPFVEST 186 Query: 193 ---RRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH----IPALAGKVLRFQK 245 +F + DP FL ++ FL V A+ V L I L+ V R +K Sbjct: 187 KKFLKFGFLDPLFLSIILFP---------FLTPVFEALNVSLFPKDTINFLSKSVNRMKK 237 Query: 246 AFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSA 305 + L + HR+ D + + + + +D L A Sbjct: 238 SRLNDKQK----HRL---------DFLQLMIDSQNSKETESHKALSDLELAAQSIIFIFA 284 Query: 306 GMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQR 365 G TTS+ L++ L + HPDVQ+++Q+EID V+ P M Y V++E R Sbjct: 285 GYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLR 344 Query: 366 FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQG 425 V + + +D+E+ G IPKG+ ++ ++ D W +P F PE F + Sbjct: 345 LFP-VAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKD 403 Query: 426 HFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467 + P + PF G R C+G A M + L +LQ+FSF Sbjct: 404 S-IDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFK 444 >2VE3-A nrPDB Length = 444 Score = 97.1 bits (240), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 120/468 (25%), Positives = 199/468 (42%), Gaps = 63/468 (13%) Query: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93 PPG LP LG L +F N + +++FG +F +L V+ ++G A R L T Sbjct: 14 PPGDFGLPWLGETL--NFLNDGDFGKKRQQQFGPIFKTRLFGKNVIFISGALANR-FLFT 70 Query: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRR-----FSVSTLRNL-----G 143 ++T + P++ + GP + + G R +R+ F TL + G Sbjct: 71 KEQETF-QATWPLSTRILLGPNA---LATQMGEIHRSRRKILYQAFLPRTLDSYLPKMDG 126 Query: 144 LGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFL 203 + + LEQW L + +V A+L G + +P+ Sbjct: 127 IVQGYLEQWGKANEVIWYPQ--------------LRRMTFDVAATLFMGEKVS-QNPQLF 171 Query: 204 RLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWD 263 + +GL ++P+ L L GK R + L +L++++ + Sbjct: 172 PWFETYIQGL-----------FSLPIPLP-NTLFGKSQRARALLLAELEKIIKARQQ--- 216 Query: 264 PAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMIL 323 QPP + E L + A+ + + L+ + L AG T ++ L+ LL+ Sbjct: 217 --QPPSE--EDALGILLAARDDNNQPLSLPELKDQILLLLFAGHETLTSALSSFCLLLGQ 272 Query: 324 HPDVQRRVQQEIDDVIGQVRRPEMGDQ-AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDI 382 H D++ RV+QE + + Q+ + + MPY V+ EV R V G + +D Sbjct: 273 HSDIRERVRQEQNKL--QLSQELTAETLKKMPYLDQVLQEVLRLIPPVGGGFRELI-QDC 329 Query: 383 EVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFL-DAQGHFVKPEAFLPFSAGRR 441 + QGF PKG + +S D ++ P +F PE F D P A +PF G R Sbjct: 330 QFQGFHFPKGWLVSYQISQTHADPDLYPDPEKFDPERFTPDGSATHNPPFAHVPFGGGLR 389 Query: 442 ACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSP 489 CLG+ AR+E+ LF T L+Q F +++ GQ +V+PSP Sbjct: 390 ECLGKEFARLEMKLFATRLIQQFDWTLLPGQ-------NLELVVTPSP 430 >3K9V-A nrPDB Length = 482 Score = 90.9 bits (224), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 54/187 (28%), Positives = 87/187 (46%), Gaps = 2/187 (1%) Query: 287 ESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPE 346 + + + L V +L A + TT+ +L W L + +P QRR+ QE+ V+ + P Sbjct: 276 QDHLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQAQRRLLQEVQSVLPDNQTPR 335 Query: 347 MGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDE 406 D +MPY A + E R VP T + + + +PKGT L N + E Sbjct: 336 AEDLRNMPYLKACLKESMRLTPSVPF-TTRTLDKPTVLGEYALPKGTVLTLNTQVLGSSE 394 Query: 407 AVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSF 466 +E +F PE +L + + P A LPF G+R C+G LA ++L L ++Q + Sbjct: 395 DNFEDSHKFRPERWLQKEKK-INPFAHLPFGIGKRMCIGRRLAELQLHLALCWIIQKYDI 453 Query: 467 SVPTGQP 473 +P Sbjct: 454 VATDNEP 460 >6C94-A nrPDB Length = 497 Score = 90.1 bits (222), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 56/194 (28%), Positives = 91/194 (46%) Query: 275 FLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQE 334 FL + +G +D +LR V G TT++ ++W L M L+P+ Q+R ++E Sbjct: 263 FLDILLDVRGESGVQLSDTDLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQQRCREE 322 Query: 335 IDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTT 394 + +++G + D A M Y T + E R VP ++ V G +P G+ Sbjct: 323 VREILGDQDSFQWEDLAKMTYLTMCMKECFRLYPPVPQVYRQLSKPVSFVDGRSLPAGSL 382 Query: 395 LITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELF 454 + ++ ++ ++ VW P F P F P AF+PFSAG R C+G+ A E+ Sbjct: 383 ISLHIYALHRNSDVWPDPEVFDPLRFSPENSSGRHPYAFIPFSAGPRNCIGQQFAMNEMK 442 Query: 455 LFFTSLLQHFSFSV 468 + L F FSV Sbjct: 443 VVTALCLLRFEFSV 456 >3EL3-A nrPDB Length = 467 Score = 82.4 bits (202), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 74/285 (25%), Positives = 124/285 (43%), Gaps = 17/285 (5%) Query: 191 CGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQ 250 C R +Y D R RL + G R ++ + L +P A + RF A Sbjct: 169 CLLRGQYMDERAERLCVALATVFR---GMYRRMVVPLGPLYRLPLPANR--RFNDALADL 223 Query: 251 ---LDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGM 307 +DE++ E R + Q P DL A L E + G+P ++ + V + + G Sbjct: 224 HLLVDEIIAERRAS---GQKPDDLLTALL-EAKDDNGDP---IGEQEIHDQVVAILTPGS 276 Query: 308 VTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFG 367 T ++T+ W L + HP+ R++ E++ V G R D + +T VI E R Sbjct: 277 ETIASTIMWLLQALADHPEHADRIRDEVEAVTGG-RPVAFEDVRKLRHTGNVIVEAMRLR 335 Query: 368 DIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHF 427 V + +T + E+ G+RIP G +I + ++ +D ++ F P+ +L + Sbjct: 336 PAVWV-LTRRAVAESELGGYRIPAGADIIYSPYAIQRDPKSYDDNLEFDPDRWLPERAAN 394 Query: 428 VKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQ 472 V A PFSAG+R C + + +L L +L + F G Sbjct: 395 VPKYAMKPFSAGKRKCPSDHFSMAQLTLITAALATKYRFEQVAGS 439 >3MDV-A nrPDB Length = 456 Score = 81.3 bits (199), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 54/189 (28%), Positives = 92/189 (48%), Gaps = 9/189 (4%) Query: 287 ESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPE 346 E + +DE L F AG T++ LA+ ++ + P++ R+Q E+D+VIG R + Sbjct: 236 EGAQDDEGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLD 295 Query: 347 MGDQAHMPYTTAVIHEVQRFGDIVP--LGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404 D + Y + V+ E R + P G + + + G R+P T L+ + + + Sbjct: 296 FEDLGRLQYLSQVLKESLR---LYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGR 352 Query: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPE-AFLPFSAGRRACLGEPLARMELFLFFTSLLQH 463 + +E P F+P+ F KP + PFS G R+C+G+ A+ME+ + LLQ Sbjct: 353 MDTYFEDPLTFNPDRFGPGAP---KPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQR 409 Query: 464 FSFSVPTGQ 472 F + GQ Sbjct: 410 LEFRLVPGQ 418 >6AYB-A nrPDB Length = 466 Score = 77.8 bits (190), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 54/195 (27%), Positives = 94/195 (48%), Gaps = 9/195 (4%) Query: 297 IVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYT 356 I++A LF AG T+S T +W L+ +I + V +V++E ++++G + + M Y Sbjct: 261 ILIAGLF-AGQHTSSITSSWTLMNVISNKKVLEKVRKEQEEIMGSDKVLDYDKVMKMDYL 319 Query: 357 TAVIHEVQRFGDIVP--LGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFR 414 A + E R + P + + M + E + + IPKG L+ + S + + P Sbjct: 320 EACMKEALR---MYPPLIMIMRMARKPRECEQYIIPKGNILVVSPSVAGRCTDTYTNPDV 376 Query: 415 FHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPR 474 F PE + + H +PF AGR C+GE A +++ + LL++F P Sbjct: 377 FDPERLTERKEHEKFKYGAVPFGAGRHKCIGENFALLQVKSIISILLRYFDMEYIGKIPD 436 Query: 475 PSHHGVFAFLVSPSP 489 PS+ + +V PSP Sbjct: 437 PSYT---SLVVGPSP 448 >4KPA-A nrPDB Length = 494 Score = 69.3 bits (168), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 60/237 (25%), Positives = 97/237 (40%), Gaps = 24/237 (10%) Query: 236 LAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENL 295 L K++ +KA Q D+LLT DP G P +DEN+ Sbjct: 239 LVDKIIADRKASGEQSDDLLTHMLNGKDPE-----------------TGEP---LDDENI 278 Query: 296 RIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPY 355 R + AG TTS L++ L ++ +P V ++ +E V+ P + Y Sbjct: 279 RYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPV-PSYKQVKQLKY 337 Query: 356 TTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVW-EKPFR 414 V++E R P + + + + KG L+ + + +D+ +W + Sbjct: 338 VGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEE 397 Query: 415 FHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTG 471 F PE F + + AF PF G+RAC+G+ A E L +L+HF F T Sbjct: 398 FRPERFENPSA--IPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTN 452 >3S79-A nrPDB Length = 503 Score = 67.8 bits (164), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 91/373 (24%), Positives = 150/373 (40%), Gaps = 43/373 (11%) Query: 112 FGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCA-AFANHSGR 170 G +G+ W+ R F + L GL + +CA + H R Sbjct: 125 IGMHEKGIIFNNNPELWKTTRPFFMKALSGPGLVR----------MVTVCAESLKTHLDR 174 Query: 171 PFRPNGLLDKAV--SNVIASLTCGRRFEYD--DPRFLRL-LDLAQEGLKEESGF--LREV 223 L++ S + LT RR D + FLR+ LD + +K + F + + Sbjct: 175 -------LEEVTNESGYVDVLTLLRRVMLDTSNTLFLRIPLDESAIVVKIQGYFDAWQAL 227 Query: 224 LNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHR---MTWDPAQPPRDL-TEAFLAEM 279 L + I L K + K ++ L+ E R T + + D TE LAE Sbjct: 228 LIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAE- 286 Query: 280 EKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVI 339 EN+ + ++ A T S +L + L L+ HP+V+ + +EI VI Sbjct: 287 ------KRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVI 340 Query: 340 GQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNL 399 G+ R ++ D + I+E R+ +V L + D+ + G+ + KGT +I N+ Sbjct: 341 GE-RDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDV-IDGYPVKKGTNIILNI 398 Query: 400 SSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTS 459 + + E + KP F E+F V F PF G R C G+ +A + + + Sbjct: 399 GRMHRLE-FFPKPNEFTLENF----AKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVT 453 Query: 460 LLQHFSFSVPTGQ 472 LL+ F GQ Sbjct: 454 LLRRFHVKTLQGQ 466 >3MZS-A nrPDB Length = 486 Score = 64.7 bits (156), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 49/179 (27%), Positives = 84/179 (46%), Gaps = 14/179 (7%) Query: 293 ENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAH 352 E+++ + ++ + G+ TTS TL W L M +VQ +++E+ + RR GD + Sbjct: 275 EDVKANITEMLAGGVNTTSMTLQWHLYEMARSLNVQEMLREEVLN----ARRQAEGDISK 330 Query: 353 M----PYTTAVIHEVQRFGDIVPLGVT--HMTSRDIEVQGFRIPKGTTLITNLSSVLKDE 406 M P A I E R P+ VT D+ +Q + IP T + + ++ +D Sbjct: 331 MLQMVPLLKASIKETLRLH---PISVTLQRYPESDLVLQDYLIPAKTLVQVAIYAMGRDP 387 Query: 407 AVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465 A + P +F P +L + L F G R C+G +A +E+ LF +L++F Sbjct: 388 AFFSSPDKFDPTRWLSKDKDLIHFRN-LGFGWGVRQCVGRRIAELEMTLFLIHILENFK 445 >5IT1-A nrPDB Length = 399 Score = 62.4 bits (150), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 58/214 (27%), Positives = 88/214 (41%), Gaps = 37/214 (17%) Query: 251 LDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTT 310 L +L+ E R A P DL A + +P+ +D L L A TT Sbjct: 193 LYQLVQERR-----ANPGDDLISALIT-----TEDPDGVIDDMFLMNAAGTLLIAAHDTT 242 Query: 311 STTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIV 370 + + G L++ PD Q + Q+ +IG + E+ R+ I Sbjct: 243 ACMIGLGTALLLDRPD-QLALLQKDPSLIGNA-----------------VEELLRYLTIG 284 Query: 371 PLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKP 430 G + ++D E+ G RI KG ++T+L S D A E P RF +P Sbjct: 285 QFGAERVATQDGEIGGVRIAKGEQVVTHLLSADFDPAFVEDPERFDITR---------RP 335 Query: 431 EAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 L F G C+G+ LAR+EL + F +L + F Sbjct: 336 APHLAFGFGAHQCIGQQLARIELQIVFGTLFRRF 369 >2W0A-A nrPDB Length = 455 Score = 62.4 bits (150), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 61/233 (26%), Positives = 103/233 (44%), Gaps = 14/233 (6%) Query: 265 AQPP-----RDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLL 319 A PP RD+ + +A ++ G P S DE + ++ +F AG T+S T +W L+ Sbjct: 214 ANPPTDKSDRDMLDVLIA-VKAETGTPRFS-ADEITGMFISMMF-AGHHTSSGTASWTLI 270 Query: 320 LMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTS 379 ++ H D V E+D++ G R +P V+ E R PL + + Sbjct: 271 ELMRHRDAYAAVIDELDELYGDGRSVSFHALRQIPQLENVLKETLRLHP--PLIILMRVA 328 Query: 380 R-DIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLD-AQGHFVKPEAFLPFS 437 + + EVQG RI +G + + + + + P F P + Q + ++PF Sbjct: 329 KGEFEVQGHRIHEGDLVAASPAISNRIPEDFPDPHDFVPARYEQPRQEDLLNRWTWIPFG 388 Query: 438 AGRRACLGEPLARMELFLFFTSLLQHFSFSV--PTGQPRPSHHGVFAFLVSPS 488 AGR C+G A M++ F+ LL+ + F + P R H + L P+ Sbjct: 389 AGRHRCVGAAFAIMQIKAIFSVLLREYEFEMAQPPESYRNDHSKMVVQLAQPA 441 >3P3Z-A nrPDB Length = 416 Score = 61.6 bits (148), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 50/168 (29%), Positives = 72/168 (42%), Gaps = 28/168 (16%) Query: 287 ESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPE 346 + +D LR +VA + AG TT+ LA + HPD ++++ PE Sbjct: 235 DGVLDDYELRTLVATVLVAGYETTNHQLALAMYDFAQHPDQWMKIKEN----------PE 284 Query: 347 MGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDE 406 + QA + EV R+ +P+ T + + D EV G RIP GT + +D Sbjct: 285 LAPQA--------VEEVLRWSPTLPVTATRVAAEDFEVNGVRIPTGTPVFMCAHVAHRDP 336 Query: 407 AVWEKPFRFHPEHFLDAQGHFVKPEA-FLPFSAGRRACLGEPLARMEL 453 V+ RF VK EA + F G CLG LAR+EL Sbjct: 337 RVFADADRFDIT---------VKREAPSIAFGGGPHFCLGTALARLEL 375 >2WX2-A nrPDB Length = 473 Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 46/186 (24%), Positives = 87/186 (46%), Gaps = 15/186 (8%) Query: 297 IVVADLFSAGMVTTSTTLAWGLLLMILHPDVQR---RVQQEIDDVIGQVRRPEMGDQAHM 353 ++VA +F AG T++ T +W +L ++HP ++ ++ +EID+ Q+ + D+ M Sbjct: 270 MIVAAMF-AGQHTSTITTSWSML-HLMHPKNKKWLDKLHKEIDEFPAQLNYDNVMDE--M 325 Query: 354 PYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPF 413 P+ + E R D L V M +++V + +PKG + + DE + P Sbjct: 326 PFAERCVRESIR-RDPPLLMVMRMVKAEVKVGSYVVPKGDIIACSPLLSHHDEEAFPNPR 384 Query: 414 RFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQ- 472 + PE G AF+ F AG C+G+ A +++ + + + F + + Sbjct: 385 LWDPERDEKVDG------AFIGFGAGVHKCIGQKFALLQVKTILATAFREYDFQLLRDEV 438 Query: 473 PRPSHH 478 P P +H Sbjct: 439 PDPDYH 444 >6M7L-A nrPDB Length = 404 Score = 59.3 bits (142), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 59/225 (26%), Positives = 95/225 (42%), Gaps = 40/225 (17%) Query: 269 RDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQ 328 RD + L + + G + +DE L + A + ++ + T + LA G LL++ HP+ Sbjct: 211 RDPGDGMLGMVARDHG---ADISDEELAGLCAVVMNSSVEQTESCLAAGTLLLLEHPEQF 267 Query: 329 RRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFR 388 +++ RPE+G+QA + E+ R+ + + D+E+ G Sbjct: 268 ALLRE----------RPELGEQA--------VEEIVRYLSVFEGLDPRTATEDVEIGGQV 309 Query: 389 IPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPL 448 I KG + +L + + + LD K + F G CLG PL Sbjct: 310 IKKGEAVFCSLLAANRADPA------------LDGFDITRKESRHVAFGHGIHHCLGAPL 357 Query: 449 ARMELFLFFTSLLQHFSFSVPTGQP------RPSHHGVFAFLVSP 487 ARMEL + FT+L+ F S+ T P RP VF L P Sbjct: 358 ARMELRIAFTTLVSRFP-SLRTAVPAEEIRFRPPSSNVFTLLELP 401 >4OQR-A nrPDB Length = 457 Score = 58.5 bits (140), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 54/208 (25%), Positives = 91/208 (43%), Gaps = 39/208 (18%) Query: 287 ESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPE 346 ++ DE L + L AG TT+ L G ++ HP+ I + P+ Sbjct: 261 DTDLTDEELTNIALILLVAGHETTANMLGLGTFALLQHPEQ-----------IANLDSPD 309 Query: 347 MGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTS-RDIEVQGFRIPKGTTLITNLSSVLKD 405 + E+ R+ IV LG + + D+E++G I KG T+ L +V +D Sbjct: 310 ------------AVEELLRYLSIVHLGTPNRAALEDVELEGQMIRKGDTVAIGLPAVNRD 357 Query: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF- 464 V+++P + +DA+ H F G CLG+ LAR+E+ + FT L F Sbjct: 358 PKVFDEPDILQLDR-VDARKHAA-------FGGGIHQCLGQQLARVEMRIGFTRLFARFP 409 Query: 465 --SFSVPTGQ----PRPSHHGVFAFLVS 486 +VP + + + +GV+A V+ Sbjct: 410 SLRLAVPAEEIKLREKSAAYGVWALPVA 437 >3N9Z-A nrPDB Length = 487 Score = 58.2 bits (139), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 50/191 (26%), Positives = 87/191 (45%), Gaps = 16/191 (8%) Query: 284 GNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVR 343 G+ + SF E+++ V ++ + G+ TTS TL W L M + VQ ++ E + R Sbjct: 267 GDSKMSF--EDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAE----VLAAR 320 Query: 344 RPEMGDQAHM----PYTTAVIHEVQRFGDIVPLGVT--HMTSRDIEVQGFRIPKGTTLIT 397 GD A M P A I E R + P+ VT D+ ++ + IP T + Sbjct: 321 HQAQGDMATMLQLVPLLKASIKETLR---LHPISVTLQRYLVNDLVLRDYMIPAKTLVQV 377 Query: 398 NLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFF 457 + ++ ++ + P F P +L + L F G R CLG +A +E+ +F Sbjct: 378 AIYALGREPTFFFDPENFDPTRWLSKDKNITYFRN-LGFGWGVRQCLGRRIAELEMTIFL 436 Query: 458 TSLLQHFSFSV 468 ++L++F + Sbjct: 437 INMLENFRVEI 447 >3ABA-A nrPDB Length = 403 Score = 58.2 bits (139), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 76/318 (23%), Positives = 125/318 (39%), Gaps = 66/318 (20%) Query: 193 RRFEYDDPRFLRLLDLAQEGLKEESG---FLREVLNAVPV-----LLHIPA--------L 236 RR + P R++D + ++ G ++ NAVP L +P + Sbjct: 109 RRMQALRPNIQRIVDEHLDAIEARGGPVDLVKTFANAVPSMVISDLFGVPVERRAEFQDI 168 Query: 237 AGKVLRF-QKAFLTQ---------LDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNP 286 A ++R Q A T+ L +L+ E R A P DL A + +P Sbjct: 169 AEAMMRVDQDAAATEAAGMRLGGLLYQLVQERR-----ANPGDDLISALIT-----TEDP 218 Query: 287 ESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPE 346 + +D L L A TT+ + G L++ PD Q + +E ++G Sbjct: 219 DGVVDDMFLMNAAGTLLIAAHDTTACMIGLGTALLLDSPD-QLALLREDPSLVGNA---- 273 Query: 347 MGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDE 406 + E+ R+ I G + +RD+E+ G RI KG ++ ++ + D Sbjct: 274 -------------VEELLRYLTIGQFGGERVATRDVELGGVRIAKGEQVVAHVLAADFDP 320 Query: 407 AVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQH--- 463 A E+P RF +P L F G C+G+ LAR+EL + F +L + Sbjct: 321 AFVEEPERFDITR---------RPAPHLAFGFGAHQCIGQQLARIELQIVFETLFRRLPG 371 Query: 464 FSFSVPTGQPRPSHHGVF 481 + P + R H VF Sbjct: 372 LRLAKPVEELRFRHDMVF 389 >3JUS-A nrPDB Length = 461 Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 46/185 (24%), Positives = 83/185 (44%), Gaps = 6/185 (3%) Query: 290 FNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGD 349 D+ + ++ L AG T+STT AW + +Q++ E V G+ P D Sbjct: 248 LTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYD 307 Query: 350 Q-AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITN--LSSVLKDE 406 Q + I E R + + + M V G+ IP G + + ++ LKD Sbjct: 308 QLKDLNLLDRCIKETLRLRPPIMI-MMRMARTPQTVAGYTIPPGHQVCVSPTVNQRLKDS 366 Query: 407 AVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSF 466 W + F+P+ +L + A++PF AGR C+GE A +++ ++++L+ + F Sbjct: 367 --WVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEF 424 Query: 467 SVPTG 471 + G Sbjct: 425 DLIDG 429 >4OQS-A nrPDB Length = 433 Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 54/208 (25%), Positives = 91/208 (43%), Gaps = 39/208 (18%) Query: 287 ESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPE 346 ++ DE L + L AG TT+ L G ++ HP+ I + P+ Sbjct: 222 DTDLTDEELTNIALLLLVAGHETTANMLGLGTFALLQHPEQ-----------IAALDSPD 270 Query: 347 MGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTS-RDIEVQGFRIPKGTTLITNLSSVLKD 405 + E+ R+ IV LG + + D+E++G I KG T+ L +V +D Sbjct: 271 ------------AVEELLRYLSIVHLGTPNRAALEDVELEGQMIRKGDTVAIGLPAVNRD 318 Query: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF- 464 V+++P + +DA+ H F G CLG+ LAR+E+ + FT L F Sbjct: 319 PKVFDEPDILQLDR-VDARKHAA-------FGGGIHQCLGQQLARVEMRIGFTRLFARFP 370 Query: 465 --SFSVPTGQ----PRPSHHGVFAFLVS 486 +VP + + + +GV+A V+ Sbjct: 371 SLRLAVPAEEIKLREKSAAYGVWALPVA 398 >5CJE-A nrPDB Length = 393 Score = 57.4 bits (137), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 54/212 (25%), Positives = 82/212 (38%), Gaps = 35/212 (16%) Query: 251 LDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTT 310 LDEL+ + R T P DL L ++ + + + + E LR + L AG TT Sbjct: 187 LDELIDDKRST----APADDL----LGDLIRTRAEDDDRLSGEELRAMAFILLVAGHETT 238 Query: 311 STTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIV 370 + G+ ++ HPD ++ A M + EV RF V Sbjct: 239 VNLITNGVHTLLTHPDQLAALR------------------ADMTLLDGAVEEVLRFEGPV 280 Query: 371 PLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKP 430 + +E+ G I +G ++ L + +D P R H D P Sbjct: 281 ETATYRYAAESMEIGGTAIAEGDPVMIGLDAAGRD------PARHPDPHVFDIH---RAP 331 Query: 431 EAFLPFSAGRRACLGEPLARMELFLFFTSLLQ 462 + L F G CLG PLAR+E + SLL+ Sbjct: 332 QGHLAFGHGIHYCLGAPLARLEARVALRSLLE 363 >4ZGX-A nrPDB Length = 489 Score = 57.4 bits (137), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 41/161 (25%), Positives = 79/161 (49%), Gaps = 6/161 (3%) Query: 287 ESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPE 346 ++ + E ++ +L + + TT+ L L + +PDVQ+ ++QE + Sbjct: 273 KAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHP 332 Query: 347 MGDQAHMPYTTAVIHEVQRFGDIVPLGV--THMTSRDIEVQGFRIPKGTTLITNLSSVLK 404 +P A + E R + P+G+ + S D+ +Q + IP GT + L S+ + Sbjct: 333 QKATTELPLLRAALKETLR---LYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGR 389 Query: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLG 445 + A++ +P R++P+ +LD +G + +PF G R CLG Sbjct: 390 NAALFPRPERYNPQRWLDIRGS-GRNFHHVPFGFGMRQCLG 429 >3L4D-A nrPDB Length = 453 Score = 55.1 bits (131), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 97/442 (21%), Positives = 185/442 (41%), Gaps = 42/442 (9%) Query: 49 VDFQNTPYCFD-QLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPIT 107 + F P F + ++++G +F++ + + V+ + + E + R V Sbjct: 19 IQFGKDPLGFMLKAKKKYGGIFTMNICGNRITVVGDVHQHSKFFTPRNEILSPRE-VYSF 77 Query: 108 QILGFGPRSQGVFLARYGPAWREQRRF-----SVSTLRNLGLGKKSLEQWVTEEAACLCA 162 + FG +GV A P REQ F +V+ +N S++ V + Sbjct: 78 MVPVFG---EGVAYAAPYPRMREQLNFLAEELTVAKFQNFA---PSIQHEVRKFMK---- 127 Query: 163 AFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLRE 222 AN + N L D S +I + C F D + L AQ K ES + Sbjct: 128 --ANWNKDEGEINILDD--CSAMIINTACQCLFGEDLRKRLDARQFAQLLAKMESCLIPA 183 Query: 223 VLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDL-TEAFLAEMEK 281 + +P +L +P R +A +L ++L+E + + + +D T LA + Sbjct: 184 AV-FLPWILKLPLPQSYRCRDARA---ELQDILSEIIIAREKEEAQKDTNTSDLLAGLLG 239 Query: 282 AKGNPESSFND-ENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQR---RVQQEIDD 337 A + + E ++VA +F AG T++ T W LL ++ P +R ++ QEID+ Sbjct: 240 AVYRDGTRMSQHEVCGMIVAAMF-AGQHTSTITTTWSLL-HLMDPRNKRHLAKLHQEIDE 297 Query: 338 VIGQVRRPEMGDQAHMPYTTAVIHE-VQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLI 396 Q+ + ++ MP+ E ++R +V L + ++V + +P+G + Sbjct: 298 FPAQLNYDNVMEE--MPFAEQCARESIRRDPPLVML--MRKVLKPVQVGKYVVPEGDIIA 353 Query: 397 TNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLF 456 + +DE + P ++PE + + AF F AG C+GE +++ Sbjct: 354 CSPLLSHQDEEAFPNPREWNPERNMK-----LVDGAFCGFGAGVHKCIGEKFGLLQVKTV 408 Query: 457 FTSLLQHFSFSVPTGQPRPSHH 478 ++L+ + F + P P++H Sbjct: 409 LATVLRDYDFELLGPLPEPNYH 430 >6M7X-A nrPDB Length = 484 Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 39/147 (26%), Positives = 72/147 (48%), Gaps = 6/147 (4%) Query: 301 DLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVI 360 +L + + TT L L + +P+VQ+ ++QE + +P A + Sbjct: 287 ELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLRAAL 346 Query: 361 HEVQRFGDIVPLGV--THMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418 E R + P+G+ + S D+ +Q + IP GT + L S+ ++ A++ +P R++P+ Sbjct: 347 KETLR---LYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQ 403 Query: 419 HFLDAQGHFVKPEAFLPFSAGRRACLG 445 +LD +G + +PF G R CLG Sbjct: 404 RWLDIRGS-GRNFYHVPFGFGMRQCLG 429 >2X2N-A nrPDB Length = 475 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 45/186 (24%), Positives = 85/186 (45%), Gaps = 15/186 (8%) Query: 297 IVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQ---QEIDDVIGQVRRPEMGDQAHM 353 ++VA +F AG T+S T W +L ++HP + ++ +EI++ Q+ + D+ M Sbjct: 270 MIVAAMF-AGQHTSSITTTWSML-HLMHPANVKHLEALRKEIEEFPAQLNYNNVMDE--M 325 Query: 354 PYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPF 413 P+ E R D L + D++V + +PKG + + DE + +P Sbjct: 326 PFAERCARESIR-RDPPLLMLMRKVMADVKVGSYVVPKGDIIACSPLLSHHDEEAFPEPR 384 Query: 414 RFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQ- 472 R+ PE +G AF+ F AG C+G+ +++ + + + F + + Sbjct: 385 RWDPERDEKVEG------AFIGFGAGVHKCIGQKFGLLQVKTILATAFRSYDFQLLRDEV 438 Query: 473 PRPSHH 478 P P +H Sbjct: 439 PDPDYH 444 >4RM4-A nrPDB Length = 396 Score = 52.8 bits (125), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 44/163 (26%), Positives = 72/163 (44%), Gaps = 28/163 (17%) Query: 302 LFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIH 361 L AG TT+ ++ + ++ P V ++ PE+ QA + Sbjct: 236 LLVAGNETTTNLISNAMYSILETPGVYEELRS----------HPELMPQA--------VE 277 Query: 362 EVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFL 421 E RF P+ + + RD E+ G I +G ++ ++S +DEA +++P H Sbjct: 278 EALRFRAPAPV-LRRIAKRDTEIGGHLIKEGDMVLAFVASANRDEAKFDRP------HMF 330 Query: 422 DAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 D + H P + F G CLG PLAR+E + TSL+ F Sbjct: 331 DIRRH---PNPHIAFGHGIHFCLGAPLARLEANIALTSLISAF 370 >6GK6-A nrPDB Length = 411 Score = 51.6 bits (122), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 53/203 (26%), Positives = 86/203 (42%), Gaps = 39/203 (19%) Query: 266 QPPRD--LTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMIL 323 + PRD ++ LAE ++ K +P L +V L AG TT +A G+LL++ Sbjct: 208 KAPRDDLISGLLLAEEQEHKLSPA------ELSSMVFLLLVAGHETTVHLIASGMLLLLS 261 Query: 324 HPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIE 383 HP +RR+ ++ ++G + + E R L + DIE Sbjct: 262 HPAERRRLDED-PGLVG-----------------SAVEEALRCEGPAELSTIRWSLEDIE 303 Query: 384 VQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV--KPEAFLPFSAGRR 441 + G R+P G + L + +D P+HF D + P + F G Sbjct: 304 LFGARVPAGEGVAAGLLAANRD-----------PQHFPDPDRFDIGRSPNRHIGFGGGIH 352 Query: 442 ACLGEPLARMELFLFFTSLLQHF 464 CLG LAR+E + F++LL+ Sbjct: 353 FCLGAMLARIEAAIAFSTLLRRL 375 >2Z36-A nrPDB Length = 413 Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 45/183 (24%), Positives = 78/183 (42%), Gaps = 27/183 (14%) Query: 282 AKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQ 341 A+ E + + L + L +AG TT+ ++ G++ ++ HP+ V+ Sbjct: 222 ARQRQEGTLDHAGLVSLAFLLLTAGHETTANMISLGVVGLLSHPEQLTVVK--------- 272 Query: 342 VRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSS 401 A+ T + E+ R+ I + + + D+E+ G I G +I ++ S Sbjct: 273 ---------ANPGRTPMAVEELLRYFTIADGVTSRLATEDVEIGGVSIKAGEGVIVSMLS 323 Query: 402 VLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLL 461 D AV++ P E A+ H L F G CLG+ LARMEL + F +L Sbjct: 324 ANWDPAVFKDPAVLDVER--GARHH-------LAFGFGPHQCLGQNLARMELQIVFDTLF 374 Query: 462 QHF 464 + Sbjct: 375 RRI 377 >5YHJ-A nrPDB Length = 413 Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 37/137 (27%), Positives = 58/137 (42%), Gaps = 15/137 (10%) Query: 337 DVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLI 396 DV QV R E+ T + EV+RF P+ + + D E G+ P+GT + Sbjct: 260 DVKEQVERGEVS-------KTEFVQEVRRFYPFFPVAAARVKT-DFEWDGYAFPEGTLTL 311 Query: 397 TNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGR----RACLGEPLARME 452 +L D ++W +P RF P F D + P F+P G C GE + Sbjct: 312 LDLYGTNHDVSIWTEPDRFDPSRFKDWKE---SPFNFIPQGGGDVDFGHRCAGEHVTIAI 368 Query: 453 LFLFFTSLLQHFSFSVP 469 L + ++++VP Sbjct: 369 LAQVIELFTKEYAYTVP 385 >3ABB-A nrPDB Length = 408 Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 45/174 (25%), Positives = 74/174 (42%), Gaps = 28/174 (16%) Query: 287 ESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPE 346 E + + + ++ L AG TT +A G L +I HP ++ID ++ R P Sbjct: 225 EGDLDHDEVVMIALVLLVAGHETTVNAIALGALTLIQHP-------EQIDVLL---RDPG 274 Query: 347 MGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDE 406 + V+ E+ RF + + M DIEV G I G ++ +++ + +D Sbjct: 275 A--------VSGVVEELLRFTSVSD-HIVRMAKEDIEVGGATIKAGDAVLVSITLMNRDA 325 Query: 407 AVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSL 460 +E P F +A+ H + F G CLG+ LAR EL + L Sbjct: 326 KAYENPDIFDARR--NARHH-------VGFGHGIHQCLGQNLARAELEIALGGL 370 >3IVY-A nrPDB Length = 433 Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 52/218 (23%), Positives = 84/218 (38%), Gaps = 39/218 (17%) Query: 259 RMTWDPAQPPRD--LTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAW 316 +M + A+ P D +T+ A+++ K +D+ V L AG TT ++ Sbjct: 226 KMAEEKAKNPADDIVTQLIQADIDGEK------LSDDEFGFFVVMLAVAGNETTRNSITQ 279 Query: 317 GLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTH 376 G++ HPD Q + +++ RPE + + T V Sbjct: 280 GMMAFAEHPD-QWELYKKV--------RPETAADEIVRWATPVT------------AFQR 318 Query: 377 MTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPF 436 RD E+ G +I KG ++ S DE V++ PF F+ P + F Sbjct: 319 TALRDYELSGVQIKKGQRVVMFYRSANFDEEVFQDPFTFNI---------LRNPNPHVGF 369 Query: 437 SA-GRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQP 473 G C+G LARM + L F ++ H P P Sbjct: 370 GGTGAHYCIGANLARMTINLIFNAVADHMPDLKPISAP 407 >3R9C-A nrPDB Length = 418 Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 36/117 (30%), Positives = 55/117 (47%), Gaps = 10/117 (8%) Query: 357 TAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFH 416 +AVI E R+ V L V+ D+ + +PKG T++ L++ +D + P RF Sbjct: 290 SAVIEETMRYDPPVQL-VSRYAGDDLTIGTHTVPKGDTMLLLLAAAHRDPTIVGAPDRFD 348 Query: 417 PEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQP 473 P+ AQ L F G CLG PLAR+E + +L F + +G+P Sbjct: 349 PDR---AQIRH------LGFGKGAHFCLGAPLARLEATVALPALAARFPEARLSGEP 396 >2Y5N-A nrPDB Length = 417 Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 49/203 (24%), Positives = 88/203 (43%), Gaps = 39/203 (19%) Query: 266 QPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHP 325 +P DL A + ++ + S +++ L + L AG +T+T +A + L++ P Sbjct: 220 EPTDDLVSALVQARDQ-----QDSLSEQELLDLAIGLLVAGYESTTTQIADFVYLLMTRP 274 Query: 326 DVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSR----D 381 +++R++ + RPE+ + + E+ R+ VPLGV R D Sbjct: 275 ELRRQL----------LDRPEL--------IPSAVEELTRW---VPLGVGTAFPRYAVED 313 Query: 382 IEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRR 441 + ++G I G ++ + + +D+A + R + P L F G Sbjct: 314 VTLRGVTIRAGEPVLASTGAANRDQAQFPDADRIDVDR---------TPNQHLGFGHGVH 364 Query: 442 ACLGEPLARMELFLFFTSLLQHF 464 CLG PLAR+EL + LLQ Sbjct: 365 HCLGAPLARVELQVALEVLLQRL 387 >6B11-A nrPDB Length = 440 Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 45/169 (26%), Positives = 73/169 (43%), Gaps = 28/169 (16%) Query: 302 LFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIH 361 L +AG TT++ + +L+++ HP R + + G V Sbjct: 276 LLAAGHETTASMVTMSVLVLLQHPTAWRELTVNPGLLPGAV------------------D 317 Query: 362 EVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFL 421 E+ R+ I G+ + DIE+ G I G L+ L++ +DEAV+ +P F + Sbjct: 318 ELLRYLSIAD-GLRRSATADIEIDGHTIRAGDGLVFLLAAANRDEAVFSEPEAF--DIHR 374 Query: 422 DAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPT 470 A+ H F G CLG+ LARMEL + ++L+ PT Sbjct: 375 SARRHVA-------FGYGPHQCLGQNLARMELEVALGAVLERLPALRPT 416 >5Z9I-A nrPDB Length = 398 Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 54/201 (26%), Positives = 81/201 (40%), Gaps = 34/201 (16%) Query: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG 348 ND + + L G +TT+ +A +L + D RV+ Sbjct: 221 KLNDSQISNIANRLLVNGHLTTAMLIANTMLCLDAFSDQDARVR---------------A 265 Query: 349 DQAHMPYTTAVIHEVQRFGDIVPL-GVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407 D++ +P A++ E R+ + P+ GV T+ ++EV G IPK L+ + +DE Sbjct: 266 DRSLVP---ALLEESMRY--MSPICGVGRATNSEVEVAGTVIPKDQLLLVWTGAANRDER 320 Query: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467 +EKP F P A L F G CLG LARME LL Sbjct: 321 QFEKPDVFDAGR---------SPNAHLGFGRGIHFCLGRQLARMESKAAVEILLDRL--- 368 Query: 468 VPTGQPRPSHHGVFAFLVSPS 488 PT + P++ F +V S Sbjct: 369 -PTLRADPANPPTFLQVVDAS 388 >1CPT-A nrPDB Length = 428 Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 61/239 (25%), Positives = 92/239 (38%), Gaps = 47/239 (19%) Query: 242 RFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVAD 301 RF + T D + T D P+D + LA K GN +D+ + Sbjct: 211 RFHETIATFYDYF---NGFTVDRRSCPKDDVMSLLAN-SKLDGN---YIDDKYINAYYVA 263 Query: 302 LFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEM-----GDQAHMPYT 356 + +AG TTS++ +IG R PE D A +P Sbjct: 264 IATAGHDTTSSSSGGA--------------------IIGLSRNPEQLALAKSDPALIP-- 301 Query: 357 TAVIHEVQRFGDIVPLGVTHMTS-RDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRF 415 ++ E R+ P+ T+ D EV+G I +G ++ + S +DE V+ P F Sbjct: 302 -RLVDEAVRW--TAPVKSFMRTALADTEVRGQNIKRGDRIMLSYPSANRDEEVFSNPDEF 358 Query: 416 HPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPR 474 F P L F G CLG+ LA++E+ +FF LL +G PR Sbjct: 359 DITRF---------PNRHLGFGWGAHMCLGQHLAKLEMKIFFEELLPKLKSVELSGPPR 408 >5LIE-A nrPDB Length = 414 Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 45/177 (25%), Positives = 70/177 (39%), Gaps = 28/177 (15%) Query: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG 348 + +D L + LFSAG TT ++A GLL + +PD + ++ + + Sbjct: 237 ALSDAELYLFFHLLFSAGAETTRNSIAGGLLALAENPDQLQTLRSDFE------------ 284 Query: 349 DQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAV 408 I E+ R+ P SR + + G I G ++ S +D +V Sbjct: 285 ------LLPTAIEEIVRWTSPSP-SKRRTASRAVSLGGQPIEAGQKVVVWEGSANRDPSV 337 Query: 409 WEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465 +++ F KP L F G CLG LAR+EL + F LL F Sbjct: 338 FDRADEFDITR---------KPNPHLGFGQGVHYCLGANLARLELRVLFEELLSRFG 385 >5OFQ-A nrPDB Length = 409 Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 53/192 (27%), Positives = 77/192 (40%), Gaps = 30/192 (15%) Query: 302 LFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIH 361 L AG TT+ + G+ M DVQ V+++I V P + ++ Y Sbjct: 238 LLVAGNETTTNLITNGVRYMTEDVDVQNEVRRDISLV------PNLVEETLRYYPP---- 287 Query: 362 EVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFL 421 +Q G I + D+E+ +I +G +I+ +S +D A +E P F Sbjct: 288 -IQAIGRI--------AAEDVELGECKIKRGQQVISWAASANRDSAKFEWPDTFVVHR-- 336 Query: 422 DAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVF 481 K + F G CLG PLARME + FT LL+ FS Q F Sbjct: 337 -------KTNPHVSFGFGIHFCLGAPLARMEGKIAFTKLLEKGGFSKVQNQSLKPIDSPF 389 Query: 482 AFLVSPSPYELC 493 F V YE+ Sbjct: 390 VFGV--KKYEIA 399 >5YSW-A nrPDB Length = 441 Score = 48.9 bits (115), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 53/237 (22%), Positives = 94/237 (39%), Gaps = 40/237 (16%) Query: 229 VLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPES 288 LL + A + ++ A + L+T+ R A P D+ + A +P Sbjct: 211 ALLQMNAPVAEAVKNADALRAFMQALVTDKR-----ANPAGDIISGLI---HHAGADP-- 260 Query: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG 348 + D+ L + L AG TT++ L G+ +++ P ++ + + V Sbjct: 261 ALTDDELINIANLLLIAGYDTTASMLGLGIFVLLQRPAQLATLRDDPSRIADAV------ 314 Query: 349 DQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAV 408 E+ R+ +V G+ D+E G IP G+T++ ++ + +D Sbjct: 315 ------------EELLRYLSVVNPGIFRFAKEDLEFAGEHIPAGSTVVVSVVATNRDARH 362 Query: 409 WEKPFRFHPEHFLDAQGHFVKPEA-FLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 W P+ LD +P L F G CLG+ LARME+ + LL+ Sbjct: 363 W-------PDPDLD----LTRPRGPHLAFGHGVHQCLGQQLARMEMQAGYAELLRRL 408 >4WMZ-A nrPDB Length = 539 Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 60/252 (23%), Positives = 97/252 (38%), Gaps = 27/252 (10%) Query: 244 QKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLF 303 QKA L+ E R D RDL ++ + G D+ + ++ + Sbjct: 258 QKAISGTYMSLIKERRKNNDIQD--RDLIDSLMKNSTYKDG---VKMTDQEIANLLIGVL 312 Query: 304 SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ-AHMPYTTAVIHE 362 G T++ T AW LL + PDVQ+ + +E V+ ++ D MP I E Sbjct: 313 MGGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLDGGKKELTYDLLQEMPLLNQTIKE 372 Query: 363 VQRFGDIVPL-GVTHMTSRDIEV--QGFRIPKGT-TLITNLSSVLKDEAV-WEKPFRFHP 417 R PL + +D+ V + IP G L++ + L+DE F H Sbjct: 373 TLRMHH--PLHSLFRKVMKDMHVPNTSYVIPAGYHVLVSPGYTHLRDEYFPNAHQFNIHR 430 Query: 418 EHFLDAQGHFVKPEA--------------FLPFSAGRRACLGEPLARMELFLFFTSLLQH 463 + A + V E +LPF GR C+GE A +L + + ++ Sbjct: 431 WNNDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAYCQLGVLMSIFIRT 490 Query: 464 FSFSVPTGQPRP 475 + P G+ P Sbjct: 491 LKWHYPEGKTVP 502 >5JLC-A nrPDB Length = 515 Score = 48.1 bits (113), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 96/452 (21%), Positives = 158/452 (34%), Gaps = 53/452 (11%) Query: 49 VDFQNTPY-CFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPIT 107 + + PY F+ ++++GD+FS L + V G D + Sbjct: 52 IPYGTKPYEFFEDCQKKYGDIFSFMLLGRIMTVYLGPKGHEFIFNAKLADVSAEAAYSHL 111 Query: 108 QILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANH 167 FG +GV EQ++F L K++ ++V A + F N Sbjct: 112 TTPVFG---KGVIYDCPNHRLMEQKKFVKG-----ALTKEAFVRYVPLIAEEIYKYFRNS 163 Query: 168 SGRPFRPN--GLLDKAVSN-VIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVL 224 N G++D VS + T R + R D A + GF Sbjct: 164 KNFKINENNSGIVDVMVSQPEMTIFTASRSLLGKEMRDKLDTDFAYLYSDLDKGF----- 218 Query: 225 NAVPVLLHIPALAGKVLR----FQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEME 280 P+ P L + R Q+A L+ E R D RDL + + Sbjct: 219 --TPINFVFPNLPLEHYRKRDHAQQAISGTYMSLIKERREKNDIQN--RDLIDELMKNST 274 Query: 281 KAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIG 340 G + D+ + ++ + G T++ T AW LL + PDVQ + QE V+ Sbjct: 275 YKDG---TKMTDQEIANLLIGVLMGGQHTSAATSAWCLLHLAERPDVQEELYQEQMRVLN 331 Query: 341 Q-VRRPEMGDQAHMPYTTAVIHEVQRFGDIVPL-GVTHMTSRDIEV--QGFRIPKGTTLI 396 + D +MP +I E R PL + RD+ + + +P+ ++ Sbjct: 332 NDTKELTYDDLQNMPLLNQMIKETLRLHH--PLHSLFRKVMRDVAIPNTSYVVPRDYHVL 389 Query: 397 TNLSSVLKDEAVWEKPFRFHPEHFLDAQ----------------GHFVK--PEAFLPFSA 438 + E + KP F+ H D G K +LPF Sbjct: 390 VSPGYTHLQEEFFPKPNEFNI-HRWDGDAASSSAAGGDEVDYGFGAISKGVSSPYLPFGG 448 Query: 439 GRRACLGEPLARMELFLFFTSLLQHFSFSVPT 470 GR C+GE A +L + + ++ + PT Sbjct: 449 GRHRCIGELFAYCQLGVLMSIFIRTMKWRYPT 480 >5M0P-A nrPDB Length = 428 Score = 48.1 bits (113), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 52/225 (23%), Positives = 82/225 (36%), Gaps = 36/225 (16%) Query: 251 LDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSA--GMV 308 L+E + E R PP A E GNP S R DL + ++ Sbjct: 203 LEEQIIETRKG--NIHPPEGTALYEFAHWEDYLGNPMDS------RTCAIDLMNTFRPLI 254 Query: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGD 368 + +++GL M +P + +++ E D Y EV+R+ Sbjct: 255 AINRFVSFGLHAMNENPITREKIKSEPD------------------YAYKFAQEVRRYYP 296 Query: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428 VP + DI+ QG IP G L ++ DE++W+ P F PE F G Sbjct: 297 FVPF-LPGKAKVDIDFQGVTIPAGVGLALDVYGTTHDESLWDDPNEFRPERFETWDG--- 352 Query: 429 KPEAFLPFSAG----RRACLGEPLARMELFLFFTSLLQHFSFSVP 469 P +P G C GE + + + + ++ VP Sbjct: 353 SPFDLIPQGGGDYWTNHRCAGEWITVIIMEETMKYFAEKITYDVP 397 >1Z8P-A nrPDB Length = 404 Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 49/210 (23%), Positives = 87/210 (41%), Gaps = 36/210 (17%) Query: 255 LTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTL 314 L E R T +P DL A + + + + + + + L + L AG ++ + + Sbjct: 199 LVERRRT----EPGDDLLSALI----RVQDDDDGRLSADELTSIALVLLLAGFESSVSLI 250 Query: 315 AWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGV 374 G L++ HPD + VRR D + +P + E+ R+ P Sbjct: 251 GIGTYLLLTHPDQ-----------LALVRR----DPSALP---NAVEEILRYI-APPETT 291 Query: 375 THMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFL 434 T + ++E+ G IP+ +T++ + +D + P RF D +GH L Sbjct: 292 TRFAAEEVEIGGVAIPQYSTVLVANGAANRDPKQFPDPHRFDVTR--DTRGH-------L 342 Query: 435 PFSAGRRACLGEPLARMELFLFFTSLLQHF 464 F G C+G PLA++E + +L F Sbjct: 343 SFGQGIHFCMGRPLAKLEGEVALRALFGRF 372 >5FSA-A nrPDB Length = 490 Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 96/474 (20%), Positives = 167/474 (35%), Gaps = 57/474 (12%) Query: 51 FQNTPY-CFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQI 109 + PY F+ R+++GDVFS L + V G D + Sbjct: 22 YGQQPYEFFESCRQKYGDVFSFMLLGKIMTVYLGPKGHEFVFNAKLSDVSAEEAYKHLTT 81 Query: 110 LGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSG 169 FG GV EQ++F+ L S +++V + + F Sbjct: 82 PVFG---TGVIYDCPNSRLMEQKKFA-----KFALTTDSFKRYVPKIREEILNYFVTDES 133 Query: 170 RPFRPNGLLDKAVSNVIAS------LTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREV 223 + V+NV+ + T R D+ R + AQ + GF Sbjct: 134 FKLKEK---THGVANVMKTQPEITIFTASRSLFGDEMRRIFDRSFAQLYSDLDKGFTP-- 188 Query: 224 LNAVPVLLHIPALAGKVLRFQKAFLTQLDEL-LTEHRMTWDPAQPPRDLTEAFLAEMEKA 282 +N V L +P + +K T + E+ L R DP RDL ++ L Sbjct: 189 INFVFPNLPLPHYWRRDAAQKKISATYMKEIKLRRERGDIDPN---RDLIDSLLIHSTYK 245 Query: 283 KGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVI--- 339 G D+ + ++ + G T+++T AW LL + P +Q + QE+ +++ Sbjct: 246 DG---VKMTDQEIANLLIGILMGGQHTSASTSAWFLLHLGEKPHLQDVIYQEVVELLKEK 302 Query: 340 -GQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRD---IEVQGFRIPKGTTL 395 G + D +P I E R +PL + I + +PKG + Sbjct: 303 GGDLNDLTYEDLQKLPSVNNTIKETLRMH--MPLHSIFRKVTNPLRIPETNYIVPKGHYV 360 Query: 396 ITNLSSVLKDEAVWEKPFRFHPEHFLDAQ------------------GHFVK--PEAFLP 435 + + E ++ P F P + A G K +LP Sbjct: 361 LVSPGYAHTSERYFDNPEDFDPTRWDTAAAKANSVSFNSSDEVDYGFGKVSKGVSSPYLP 420 Query: 436 FSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQ-PRPSHHGVFAFLVSPS 488 F GR C+GE A ++L T+ + + +++ + P P + + P+ Sbjct: 421 FGGGRHRCIGEQFAYVQLGTILTTFVYNLRWTIDGYKVPDPDYSSMVVLPTEPA 474 >5DQN-A nrPDB Length = 426 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 49/204 (24%), Positives = 81/204 (39%), Gaps = 34/204 (16%) Query: 272 TEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRV 331 TE + ++ +A + E +D+ V L AG TT ++ G++ +PD Sbjct: 219 TEDIVTKLIEADIDGEK-LSDDEFGFFVVMLAVAGNETTRNSITHGMIAFAQNPDQWELY 277 Query: 332 QQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTS-RDIEVQGFRIP 390 ++E RPE E+ R+ P+ T+ D+E+ G +I Sbjct: 278 KKE---------RPE-----------TAADEIVRWA--TPVSAFQRTALEDVELGGVQIK 315 Query: 391 KGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSA-GRRACLGEPLA 449 KG ++ + S DE V+E P F+ P + F G C+G LA Sbjct: 316 KGQRVVMSYRSANFDEEVFEDPHTFN---------ILRSPNPHVGFGGTGAHYCIGANLA 366 Query: 450 RMELFLFFTSLLQHFSFSVPTGQP 473 RM + L F ++ + P G P Sbjct: 367 RMTINLIFNAIADNMPDLKPIGAP 390 >4YZR-A nrPDB Length = 405 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 46/199 (23%), Positives = 76/199 (38%), Gaps = 32/199 (16%) Query: 266 QPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHP 325 +P DL + E S +++ L ++ L AG+ TT L G L ++ H Sbjct: 207 KPKDDLISKLVHAEENG-----SKLSEKELYSMLFLLVVAGLETTVNLLGSGTLALLQHK 261 Query: 326 DVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQ 385 +++Q+ PEM + E+ R+ V + D + Sbjct: 262 KECEKLKQQ----------PEM--------IATAVEELLRYTSPVVMMANRWAIEDFTYK 303 Query: 386 GFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLG 445 G I +G + + S +D +E P L+ P + F G CLG Sbjct: 304 GHSIKRGDMIFIGIGSANRDPNFFENP------EILNINR---SPNRHISFGFGIHFCLG 354 Query: 446 EPLARMELFLFFTSLLQHF 464 PLAR+E + F +LL+ F Sbjct: 355 APLARLEGHIAFKALLKRF 373 >6G71-A nrPDB Length = 405 Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 33/97 (34%), Positives = 44/97 (45%), Gaps = 12/97 (12%) Query: 358 AVIHEVQRFGDIVPLG-VTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFH 416 AV E R+ + P+G V T D E+ G+ IP+G L + S +D +VW P RF Sbjct: 271 AVFEESIRW--VAPIGMVPRQTVVDTELDGYFIPRGAKLGLCILSANRDRSVWSDPDRFD 328 Query: 417 PEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMEL 453 E EA L F G CLG AR ++ Sbjct: 329 IER---------GSEAHLAFGKGVHVCLGAWAARSQV 356 >5HIW-A nrPDB Length = 398 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 68/271 (25%), Positives = 108/271 (39%), Gaps = 41/271 (15%) Query: 205 LLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDP 264 L L +E + E +R+++ +V V+ P + + A QL E+ + Sbjct: 139 LFGLPEERIAENDALIRKMIRSV-VMPQDPVVVAEGRSAHAAMEAQLREIAER-----EV 192 Query: 265 AQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILH 324 A P ++ L E+ +A E E VV L TTS LA L+ ++ H Sbjct: 193 AHP----SDTLLGEIARAI-VAEGLGGVEACEGVVLTLILGSYETTSWMLANLLVALLAH 247 Query: 325 PDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV 384 PD +++Q+ P + QA I E R+ G+ R+ + Sbjct: 248 PDAMNQLRQQ----------PSLLPQA--------IEESTRWCSSAA-GIVRFVEREATI 288 Query: 385 QGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444 G + GT L +L + DE ++ +P F +P L F G C+ Sbjct: 289 GGETLAAGTILYLSLIARHYDEEIYPRPETFDIHR---------RPVGMLNFGGGLHYCV 339 Query: 445 GEPLARMELFLFFTSLLQHFSF--SVPTGQP 473 G PLARME + + LL+ F + PT QP Sbjct: 340 GAPLARMEARVGVSLLLERFPALRADPTVQP 370 >5Y1I-A nrPDB Length = 403 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 42/164 (25%), Positives = 70/164 (42%), Gaps = 25/164 (15%) Query: 302 LFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIH 361 L AG TT+ +A G L ++ +P+ V+ D + + Sbjct: 234 LLGAGHETTANMIALGTLALLENPEQLAEVRDSDDPKV----------------IVNTVE 277 Query: 362 EVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHF 420 E+ R+ I V + + DIE+ G I G ++ L++ D ++ E P R H Sbjct: 278 ELLRYLTIAQDTVRRIAAEDIEIGGVVIKAGEGIVFPLNAANWDPDLYPEAPDRLDI-HR 336 Query: 421 LDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 +A+ H L F G CLG LAR+EL + +++LL+ Sbjct: 337 ANARRH-------LAFGYGVHQCLGATLARVELQIVYSTLLRRI 373 >4YT3-A nrPDB Length = 410 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 50/203 (24%), Positives = 94/203 (46%), Gaps = 31/203 (15%) Query: 273 EAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQ 332 + ++++ K++ + E +DE +R + + AG+ TTS LA +L+ D + V Sbjct: 212 DDIISDLLKSEVDGEMFTDDEVVRTTML-ILGAGVETTSHLLA-NSFYSLLYDD--KEVY 267 Query: 333 QEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFG-DIVPLGVTHMTSRDIEVQGFRIPK 391 QE+ ++ + E+ RF +++ L T D ++ G + + Sbjct: 268 QEL--------------HENLDLVPQAVEEMLRFRFNLIKLDRT--VKEDNDLLGVELKE 311 Query: 392 GTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARM 451 G +++ +S+ DE ++E PF + H + + H L F G CLG PLAR+ Sbjct: 312 GDSVVVWMSAANMDEEMFEDPFTLNI-HRPNNKKH-------LTFGNGPHFCLGAPLARL 363 Query: 452 ELFLFFTSLLQHFSF--SVPTGQ 472 E + T+ L+ F +VP+ Q Sbjct: 364 EAKIALTAFLKKFKHIEAVPSFQ 386 >2RFC-A nrPDB Length = 343 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 37/157 (23%), Positives = 65/157 (41%), Gaps = 13/157 (8%) Query: 308 VTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFG 367 +T + + +LL+I + + + VI + P++ D A + + + E R+ Sbjct: 173 LTMDEKIKYIMLLIIGGNETTTNLIGNMIRVIDE--NPDIIDDA-LKNRSGFVEETLRYY 229 Query: 368 DIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHF 427 + + D + +I KG +I L S +DE +++P F Sbjct: 230 SPIQFLPHRFAAEDSYINNKKIKKGDQVIVYLGSANRDETFFDEPDLFK----------I 279 Query: 428 VKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 + E L F G CLG PLAR+E + +L HF Sbjct: 280 GRREMHLAFGIGIHMCLGAPLARLEASIALNDILNHF 316 >2X9P-A nrPDB Length = 404 Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 51/194 (26%), Positives = 78/194 (40%), Gaps = 33/194 (17%) Query: 274 AFLAEMEKAKGNPE--SSFNDENL---RI--VVADLFSAGMVTTSTTLAWGLLLMILHPD 326 A L E ++A+ P+ S ND L R+ + L AG+ + ++ + G++L+ HPD Sbjct: 203 AGLVEHKRAEPGPDIISRLNDGELTEDRVAHLAMGLLFAGLDSVASIMDNGVVLLAAHPD 262 Query: 327 VQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQG 386 QR DV+ + V+ + G ++P S D+E G Sbjct: 263 -QRAAALADPDVMARA-------------VEEVLRTARAGGSVLP---PRYASEDMEFGG 305 Query: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446 I G ++ +L DE + P F P L F G C+G Sbjct: 306 VTIRAGDLVLFDLGLPNFDERAFTGPEEFDAAR---------TPNPHLTFGHGIWHCIGA 356 Query: 447 PLARMELFLFFTSL 460 PLAR+EL FT L Sbjct: 357 PLARLELRTMFTKL 370 >1Q5D-A nrPDB Length = 419 Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 42/177 (23%), Positives = 72/177 (40%), Gaps = 27/177 (15%) Query: 288 SSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEM 347 S + + L +V + +AG TT +A+ +L ++ P+ V+ E P + Sbjct: 237 SRLSTKELVALVGAIIAAGTDTTIYLIAFAVLNLLRSPEALELVKAE----------PGL 286 Query: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407 A + EV RF +I+ +G +D+E G I KG + + S L+D Sbjct: 287 MRNA--------LDEVLRFDNILRIGTVRFARQDLEYCGASIKKGEMVFLLIPSALRDGT 338 Query: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 V+ +P F A L + G C G LAR+E + ++ + F Sbjct: 339 VFSRPDVFDVRR---------DTSASLAYGRGPHVCPGVSLARLEAEIAVGTIFRRF 386 >2VZM-A nrPDB Length = 436 Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 51/218 (23%), Positives = 80/218 (36%), Gaps = 34/218 (15%) Query: 273 EAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQ 332 E L+ + + S E L + L AG TT +A G+ ++ HPD Sbjct: 231 EDLLSALVRTSDEDGSRLTSEELLGMAHILLVAGHETTVNLIANGMYALLSHPDQ----- 285 Query: 333 QEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKG 392 + +R A M + E+ R+ V +++ G IP G Sbjct: 286 ------LAALR-------ADMTLLDGAVEEMLRYEGPVESATYRFPVEPVDLDGTVIPAG 332 Query: 393 TTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452 T++ L+ + + P RF D GH L F G C+G PLAR+E Sbjct: 333 DTVLVVLADAHRTPERFPDPHRFDIRR--DTAGH-------LAFGHGIHFCIGAPLARLE 383 Query: 453 LFLFFTSLLQH---FSFSVPTGQ----PRPSHHGVFAF 483 + +LL+ + V G+ P P G+ A Sbjct: 384 ARIAVRALLERCPDLALDVSPGELVWYPNPMIRGLKAL 421 >1WIY-A nrPDB Length = 389 Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 46/179 (25%), Positives = 70/179 (39%), Gaps = 23/179 (12%) Query: 286 PESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP 345 P S E L AG T ++ L W LL+ PD Q+RV + + + Sbjct: 202 PLSHLPRERALSEAVTLLVAGHETVASALTWSFLLLSHRPDWQKRVAESEEAALAAF--- 258 Query: 346 EMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKD 405 +A Y A I +T R + + R+P+GTTL+ LS + Sbjct: 259 ---QEALRLYPPAWI-------------LTRRLERPLLLGEDRLPQGTTLV--LSPYVTQ 300 Query: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 + + F PE FL +G + PF G+R CLG A +E + + + F Sbjct: 301 RLYFPEGEAFQPERFLAERG--TPSGRYFPFGLGQRLCLGRDFALLEGPIVLRAFFRRF 357 >3MGX-A nrPDB Length = 415 Score = 45.4 bits (106), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 31/107 (28%), Positives = 49/107 (45%), Gaps = 10/107 (9%) Query: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418 V+ EV R+ + V +T+ D+ + G +P GT ++ L + +D A ++ P F P Sbjct: 290 VVEEVLRWTSPA-MHVLRVTTADVTINGRDLPSGTPVVAWLPAANRDPAEFDDPDTFLPG 348 Query: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465 KP + F G CLG LAR+EL + L + S Sbjct: 349 R---------KPNRHITFGHGMHHCLGSALARIELSVVLRVLAERVS 386 >5LIV-A nrPDB Length = 450 Score = 45.4 bits (106), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 67/267 (25%), Positives = 101/267 (37%), Gaps = 40/267 (14%) Query: 211 EGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRD 270 E L E +R +L + V +H PA + R L + E++ + RD Sbjct: 196 EKLHETDERVRAMLRGL-VRMHDPAAVAESQRAYGETLGLITEVVE---------RESRD 245 Query: 271 LTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRR 330 ++ L E+ + E E R +V L G TTS +A + ++ HPD R Sbjct: 246 TSDTLLGEILRTL-KAEHMDTIEASRQIVLSLILGGYETTSWLVANTIHALLAHPDTLAR 304 Query: 331 VQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIP 390 V+Q D + +P A I E R+ GV M RD+ + + Sbjct: 305 VRQ---------------DPSLLP---AAIEEGMRWCP-SSFGVLRMVERDVRLDDQALS 345 Query: 391 KGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKP-EAFLPFSAGRRACLGEPLA 449 GT + + DE + P + + KP A F G C+G PLA Sbjct: 346 AGTVVCLAGIAGNYDETAYPSPEVYDIDR---------KPLPAANVFGGGAHFCVGAPLA 396 Query: 450 RMELFLFFTSLLQHFSFSVPTGQPRPS 476 RME + +LL F + RPS Sbjct: 397 RMEARVGLQALLARFPGLRAVPEERPS 423 >6A7J-A nrPDB Length = 411 Score = 45.4 bits (106), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 48/216 (22%), Positives = 82/216 (37%), Gaps = 40/216 (18%) Query: 265 AQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILH 324 A P DLT A +A E DE + + + +AG TT + + + + +H Sbjct: 205 ANPGDDLTSALIAASEDG-----DHLTDEEILNTLQLIIAAGHETTISLIVNVVEALAIH 259 Query: 325 PDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV 384 P+ +++V +P+ VI E R+ + + DIEV Sbjct: 260 PEQRKKVLS-----------------GEIPWE-GVIEETLRWNTPTSHVLIRFATEDIEV 301 Query: 385 QGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV---KPEAFLPFSAGRR 441 +PKG L+ + ++ +DE E + G F P + F G Sbjct: 302 GDKVLPKGEGLVVSFGALGRDE-----------EQYGPTAGDFDATRTPNRHIAFGHGPH 350 Query: 442 ACLGEPLARMELFLFFTSLLQHF---SFSVPTGQPR 474 C G L+R+E + +L + F +VP + R Sbjct: 351 VCPGAALSRLEAGIALPALYERFPELDLAVPAAELR 386 >6FYJ-A nrPDB Length = 421 Score = 45.4 bits (106), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 29/119 (24%), Positives = 50/119 (42%), Gaps = 8/119 (6%) Query: 355 YTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFR 414 Y+ + EV+RF P V + +D +G++ +GT + +L D +W+ P Sbjct: 279 YSQMFVQEVRRFYPFFPF-VVALVKKDFTWKGYKFEEGTLTLLDLYGTNHDPEIWKNPDV 337 Query: 415 FHPEHFLDAQGHFVKPEAFLPFSAGR----RACLGEPLARMELFLFFTSLLQHFSFSVP 469 F P+ F +G P +F+P G C GE + + + L + VP Sbjct: 338 FSPDRFAKWEG---SPFSFIPQGGGDYFMGHRCAGEWVTIEVMKVSLDYLTNRMDYEVP 393 >6F88-A nrPDB Length = 400 Score = 45.4 bits (106), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 68/273 (24%), Positives = 101/273 (36%), Gaps = 40/273 (14%) Query: 205 LLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDP 264 L E L E +R +L + V +H PA + R L + E++ Sbjct: 140 LFGFPAEKLHETDERVRAMLRGL-VRMHDPAAVAESQRAYGETLGLITEVVERE------ 192 Query: 265 AQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILH 324 RD ++ L E+ + E E R +V L G TTS +A + ++ H Sbjct: 193 ---SRDTSDTLLGEILRTL-KAEHMDTIEASRQIVLSLILGGYETTSWLVANTIHALLAH 248 Query: 325 PDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV 384 PD RV+Q D + +P A I E R+ GV M RD+ + Sbjct: 249 PDTLARVRQ---------------DPSLLP---AAIEEGMRWCP-SNFGVLRMVERDVRL 289 Query: 385 QGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKP-EAFLPFSAGRRAC 443 + GT + + DE + P + + KP A F G C Sbjct: 290 DDQALSAGTVVCLAGIAGNYDETAYPSPEVYDIDR---------KPLPAANVFGGGAHFC 340 Query: 444 LGEPLARMELFLFFTSLLQHFSFSVPTGQPRPS 476 +G PLARME + +LL F + RPS Sbjct: 341 VGAPLARMEARVGLQALLARFPGLRAVPEERPS 373 >1EHE-A nrPDB Length = 403 Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 52/223 (23%), Positives = 86/223 (38%), Gaps = 39/223 (17%) Query: 254 LLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTT 313 +L E R+ +P D+ E K GN + S + ++I L AG T Sbjct: 197 ILVEQRLV----EPKDDIISKLCTEQVKP-GNIDKS---DAVQIAFL-LLVAGNATMVNM 247 Query: 314 LAWGLLLMILHPDVQRRVQQEIDDVIGQVR-RPEMGDQAHMPYTTAVIHEVQRFGDIVPL 372 +A G+ + HPD + Q++ P + Q + E+ R+ L Sbjct: 248 IALGVATLAQHPDQ-----------LAQLKANPSLAPQ--------FVEELCRYHTASAL 288 Query: 373 GVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEA 432 + D+ + + +I + S +DE V+E P F+ P+ Sbjct: 289 AIKRTAKEDVMIGDKLVRANEGIIASNQSANRDEEVFENPDEFN-------MNRKWPPQD 341 Query: 433 FLPFSAGRRACLGEPLARMELFLFFTSLLQHF---SFSVPTGQ 472 L F G C+ E LA+ EL F++L Q F +VP G+ Sbjct: 342 PLGFGFGDHRCIAEHLAKAELTTVFSTLYQKFPDLKVAVPLGK 384 >6GMF-A nrPDB Length = 397 Score = 45.1 bits (105), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 34/112 (30%), Positives = 51/112 (45%), Gaps = 10/112 (8%) Query: 350 QAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVW 409 QA + AV+ EV R+ + T D+E+ RIP + ++ L+S +DE+ + Sbjct: 260 QADLSLVPAVVEEVLRYESPAQC-IFRQTMTDVEIGDERIPARSVVLPLLASANRDESRF 318 Query: 410 EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLL 461 P RF D +GH L F C+G PLAR+E + LL Sbjct: 319 PDPDRFDIHR--DTKGH-------LAFGLDIHFCIGAPLARLEAKVMLEVLL 361 >6CR2-A nrPDB Length = 477 Score = 44.7 bits (104), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 43/195 (22%), Positives = 78/195 (40%), Gaps = 22/195 (11%) Query: 292 DENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ- 350 DE + ++ L AG ++S+T +W +L + PD+ + QE V+G P D Sbjct: 248 DEEIAHMMIALLMAGQHSSSSTASWIVLRLATRPDIMEELYQEQIRVLGSDLPPLTYDNL 307 Query: 351 AHMPYTTAVIHEVQRFGDIVPL-GVTHMTSRDIEVQG--FRIPKGTTLITNLSSVLKDEA 407 + VI E R P+ + + V G + IP ++++ + E Sbjct: 308 QKLDLHAKVIKETLRLH--APIHSIIRAVKNPMAVDGTSYVIPTSHNVLSSPGVTARSEE 365 Query: 408 VWEKPFRFHPEHFLDAQGHFVKPEA----------------FLPFSAGRRACLGEPLARM 451 + P ++P + + + + +LPF AGR C+GE A + Sbjct: 366 HFPNPLEWNPHRWDENIAASAEDDEKVDYGYGLVSKGTNSPYLPFGAGRHRCIGEQFAYL 425 Query: 452 ELFLFFTSLLQHFSF 466 +L L++ F F Sbjct: 426 QLGTITAVLVRLFRF 440 >2ZBZ-A nrPDB Length = 412 Score = 44.7 bits (104), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 46/183 (25%), Positives = 75/183 (40%), Gaps = 22/183 (12%) Query: 298 VVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEM-----GDQAH 352 +VAD + G + ++ +LL+I + + VI + PE D++ Sbjct: 219 LVADQLANGEIDREELISTAMLLLIAGHETTASMTSL--SVITLLDHPEQYAALRADRSL 276 Query: 353 MPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKP 412 +P + E+ R+ I + + + DIEV+G I G +I S +D V+E P Sbjct: 277 VP---GAVEELLRYLAIADIAGGRVATADIEVEGQLIRAGEGVIVVNSIANRDGTVYEDP 333 Query: 413 FRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQH---FSFSVP 469 DA L F G CLG+ LAR+EL + +L+ +VP Sbjct: 334 ---------DALDIHRSARHHLAFGFGVHQCLGQNLARLELEVILNALMDRVPTLRLAVP 384 Query: 470 TGQ 472 Q Sbjct: 385 VEQ 387 >5D3U-A nrPDB Length = 427 Score = 44.7 bits (104), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 8/97 (8%) Query: 377 MTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPF 436 + ++D+E+ G RI G TL L S +D ++E+P F + A+ L F Sbjct: 320 VAAKDVEMGGVRIEAGQTLALFLGSANRDANMFERPNDFDLDRPNSAR--------HLSF 371 Query: 437 SAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQP 473 G ACL L ++L F+ +LL F G+P Sbjct: 372 GQGVHACLAAQLISLQLKWFYVALLNRFPGIRTAGEP 408 >1LG9-A nrPDB Length = 398 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 46/175 (26%), Positives = 68/175 (38%), Gaps = 29/175 (16%) Query: 291 NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350 DE LR + AG S + G+L M+ HP ++ID G + + Sbjct: 222 TDEELRGFCVQVMLAGDDNISGMIGLGVLAMLRHP-------EQIDAFRGDEQSAQRAVD 274 Query: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSR-DIEVQGFRIPKGTTLITNLSSVLKDEAVW 409 + Y T VP T +R D+ + G I KG ++I +L + +D A+ Sbjct: 275 ELIRYLT------------VPYSPTPRIAREDLTLAGQEIKKGDSVICSLPAANRDPALA 322 Query: 410 EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 R +P + F G CLG LAR+EL FT L + F Sbjct: 323 PDVDRLDVTR---------EPIPHVAFGHGVHHCLGAALARLELRTVFTELWRRF 368 >3TYW-A nrPDB Length = 417 Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 48/197 (24%), Positives = 78/197 (39%), Gaps = 31/197 (15%) Query: 266 QPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHP 325 + PRD + L GN E L + +AG TT++ +A LL++ P Sbjct: 214 EEPRDDLISKLVTDHLVPGN----VTTEQLLSTLGITINAGRETTTSMIALSTLLLLDRP 269 Query: 326 DVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQ 385 ++ ++++ D MP + V D +PL V + DIE+ Sbjct: 270 ELPAELRKDPD---------------LMPAAVDELLRVLSVADSIPLRVA---AEDIELS 311 Query: 386 GFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLG 445 G +P +I L+ D ++ P R F H V F G C+G Sbjct: 312 GRTVPADDGVIALLAGANHDPEQFDDPERVD---FHRTDNHHVA------FGYGVHQCVG 362 Query: 446 EPLARMELFLFFTSLLQ 462 + LAR+EL + +LL+ Sbjct: 363 QHLARLELEVALETLLR 379 >3A50-A nrPDB Length = 411 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 44/180 (24%), Positives = 68/180 (37%), Gaps = 27/180 (15%) Query: 273 EAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQ 332 +A L+ + + E L + L AG TT + G+L ++ HPD QR++ Sbjct: 204 DALLSSLLAVSDMDGDRLSQEELVAMAMLLLIAGHETTVNLIGNGVLALLTHPD-QRKLL 262 Query: 333 QEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKG 392 E +I ++ + E RF V T+ D+ G IP G Sbjct: 263 AEDPSLI-----------------SSAVEEFLRFDSPVSQAPIRFTAEDVTYSGVTIPAG 305 Query: 393 TTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452 ++ L++ +D +P R DA G F G CLG LAR+E Sbjct: 306 EMVMLGLAAANRDADWMPEPDRLDITR--DASGGVF-------FGHGIHFCLGAQLARLE 356 >4GGV-A nrPDB Length = 418 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 50/193 (25%), Positives = 78/193 (40%), Gaps = 31/193 (16%) Query: 273 EAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQ 332 E L + +A+ + E D + V L G +TT+ TL +L + P+V +V+ Sbjct: 226 EDLLTHLVQAEVDGER-LTDNEIVNVANILLVTGHITTTMTLGNTVLCLDADPEVAAKVR 284 Query: 333 QEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVP-LGVTHMTSRDIEVQGFRIPK 391 D++ +P I E R + P + TSR++EV G IPK Sbjct: 285 ---------------ADRSLVP---GAIEEALRV--LSPSAALARGTSREVEVAGTVIPK 324 Query: 392 GTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARM 451 ++ L + +D + P + P D HF F G CLG PLAR+ Sbjct: 325 DQIVMLWLGAGNRDPRQFTDPEVYDPTR--DPNPHF-------GFGRGIHFCLGAPLARL 375 Query: 452 ELFLFFTSLLQHF 464 E + +L F Sbjct: 376 EGRVALNALFDRF 388 >6A7I-A nrPDB Length = 411 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 53/218 (24%), Positives = 83/218 (38%), Gaps = 46/218 (21%) Query: 266 QPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHP 325 P DLT A +A E DE + + + +AG TT + + + + HP Sbjct: 206 NPGDDLTSALIAASENG-----DHLTDEEIVNTLQLIIAAGHETTISLIVNVVEALQTHP 260 Query: 326 DVQRRV-QQEI--DDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDI 382 + +++V EI D VI + R + T H + RF + DI Sbjct: 261 EQRKKVLNGEIGWDGVIEETLR----------WNTPTSHVLIRFA-----------TEDI 299 Query: 383 EVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV---KPEAFLPFSAG 439 EV +PKG LI + ++ +DE E + G F P + F G Sbjct: 300 EVGDKILPKGEGLIISFGALGRDE-----------EQYGPTAGEFDATRTPNRHIAFGHG 348 Query: 440 RRACLGEPLARMELFLFFTSLLQHF---SFSVPTGQPR 474 C G L+R+E + +L + F +VP R Sbjct: 349 PHVCPGAALSRLEAGIALPALYERFPELDLAVPASDLR 386 >5NWS-A nrPDB Length = 435 Score = 42.7 bits (99), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 44/204 (21%), Positives = 80/204 (39%), Gaps = 24/204 (11%) Query: 271 LTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRR 330 LT+ L+E+ +A+ + +D ++ L AG T++ + G ++ HP Sbjct: 233 LTDDLLSELIRAQDDDGGRLSDIETVTMILTLVLAGHETSAHLIGNGTAALLTHPGQWAL 292 Query: 331 VQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIP 390 +++ D A +P +HE+ R+ V + + D+E+ G + Sbjct: 293 LRK---------------DPALLPR---AVHELMRWCGSVHVARLRYATEDLELAGTPVA 334 Query: 391 KGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLAR 450 +G + L S D + P R + Q E + F G CLG LAR Sbjct: 335 RGDAVQLVLVSANFDPRHYSDPDRLDITRHQEGQA-----ENHVGFGHGIHYCLGATLAR 389 Query: 451 MELFLFFTSLLQHF-SFSVPTGQP 473 E + LL+ + ++ G P Sbjct: 390 QEGEVALARLLETYPDLALADGDP 413 >5XW2-A nrPDB Length = 419 Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 44/164 (26%), Positives = 71/164 (43%), Gaps = 30/164 (18%) Query: 302 LFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIH 361 L AG +TT+ + +L + +P+ RV+ D++ +P ++ Sbjct: 253 LLIAGYLTTTMLIGNTVLCLDSYPEQAARVR---------------ADRSLIP---GLLE 294 Query: 362 EVQRFGDIVPLGVTH-MTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHF 420 E RF + P+ T+ T+RD+EV G R+ ++ + +D + +P E F Sbjct: 295 ESMRF--LSPVAATYRATTRDVEVAGQRLSADQMVMVWFGAANRDARQFAEP-----ELF 347 Query: 421 LDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 +G P L F G CLG PLARME + LL F Sbjct: 348 DMTRG----PNPHLGFGRGIHFCLGGPLARMEGRVALDHLLDRF 387 >5XNT-A nrPDB Length = 411 Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 49/203 (24%), Positives = 92/203 (45%), Gaps = 31/203 (15%) Query: 273 EAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQ 332 + ++++ KA+ + E +DE +R + + AG+ TTS LA +L+ D + V Sbjct: 212 DDIISDLLKAEVDGEMFTDDEVVRTTML-ILGAGVETTSHLLA-NSFYSLLYDD--KEVY 267 Query: 333 QEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFG-DIVPLGVTHMTSRDIEVQGFRIPK 391 QE+ ++ + E+ R+ +++ L T D ++ G + + Sbjct: 268 QEL--------------HENLDLVPQAVEEMLRYRFNLIKLDRT--VKEDNDLLGVELKE 311 Query: 392 GTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARM 451 G ++ +S+ DE ++E F + H + + H L F G CLG PLAR+ Sbjct: 312 GENVVVWMSAANLDEEMFEDAFTLNI-HRPNNKKH-------LTFGNGPHFCLGAPLARL 363 Query: 452 ELFLFFTSLLQHFSF--SVPTGQ 472 E + T+ L+ F +VP+ Q Sbjct: 364 EAKIALTTFLKKFKHIEAVPSFQ 386 >5VWS-A nrPDB Length = 393 Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 56/229 (24%), Positives = 94/229 (41%), Gaps = 38/229 (16%) Query: 239 KVLRFQKAFLTQLDELLTEHRMTWDPAQPPRD--LTEAFLAEMEKAKGNPESSFNDENLR 296 ++ R A +T++++ L EH + PRD LT AE+E + + E N +L Sbjct: 173 ELARTVAAAMTEMNDYLREHCRS--RRTHPRDDLLTRLVQAEVEGKRLDLEEVVNTASL- 229 Query: 297 IVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYT 356 L AG +TT+ + +L + HP+ ++ V+ D + +P Sbjct: 230 -----LLLAGHLTTTVLIGNTMLCLWDHPEAEKAVR---------------ADPSLIP-- 267 Query: 357 TAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFH 416 A + E R L +T+RD+ + G IP ++ + S D+ + P RF Sbjct: 268 -AALEESLRLRSPF-LQAGRVTTRDVTIAGETIPANRFVMAWILSANHDDRRFPDPERF- 324 Query: 417 PEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465 + GH + F G CLG L R+E + LL F+ Sbjct: 325 -DLHRQTTGH-------IAFGHGVHFCLGAQLGRLEGRIALERLLGRFT 365 >6F0B-A nrPDB Length = 395 Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 36/157 (22%), Positives = 64/157 (40%), Gaps = 29/157 (18%) Query: 298 VVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTT 357 V+ L G TT++T++ L+ L P+ V + H Sbjct: 226 VILMLIVGGYDTTASTISLSLVSYALQPEKFSVVHE------------------HPERIP 267 Query: 358 AVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHP 417 ++ E+ R+ + LG+ + + D+EV G + G ++ L +DE+V+ P Sbjct: 268 LLVEELLRYHTVSQLGLGRIATEDVEVGGVTVRAGQMVVAALPLANRDESVFPNPDEL-- 325 Query: 418 EHFLDAQGHFVKPEA-FLPFSAGRRACLGEPLARMEL 453 F +P + F G C+G+ LAR+EL Sbjct: 326 --------DFDRPSVPHVGFGYGPHQCVGQALARVEL 354 >3AWQ-A nrPDB Length = 415 Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 1/66 (1%) Query: 355 YTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFR 414 Y + EV+RF P V S+D E +G P+G ++ +L D A W P Sbjct: 273 YAELFVQEVRRFYPFFP-AVVARASQDFEWEGMAFPEGRQVVLDLYGSNHDAATWADPQE 331 Query: 415 FHPEHF 420 F PE F Sbjct: 332 FRPERF 337 >2IJ7-A nrPDB Length = 396 Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 44/210 (20%), Positives = 82/210 (39%), Gaps = 36/210 (17%) Query: 270 DLTEAFLAEMEKAKGNPE-SSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQ 328 ++T + E+ + + +P S +DE + F AG+++T + L L+ +I P ++ Sbjct: 197 NITTGLMGELSRLRKDPAYSHVSDELFATIGVTFFGAGVISTGSFLTTALISLIQRPQLR 256 Query: 329 RRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFR 388 + + +PE+ A + E+ R G+ + + DI+V Sbjct: 257 NLLHE----------KPEL--------IPAGVEELLRINLSFADGLPRLATADIQVGDVL 298 Query: 389 IPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV---KPEAFLPFSAGRRACLG 445 + KG ++ L F PEHF + + P + L F G+ C G Sbjct: 299 VRKGELVLVLLEGA-----------NFDPEHFPNPGSIELDRPNPTSHLAFGRGQHFCPG 347 Query: 446 EPLARMELFLFFTSLLQHF---SFSVPTGQ 472 L R + +LL+ +VP Q Sbjct: 348 SALGRRHAQIGIEALLKKMPGVDLAVPIDQ 377 >6GII-A nrPDB Length = 479 Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 32/103 (31%), Positives = 46/103 (44%), Gaps = 9/103 (8%) Query: 358 AVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHP 417 A E R+ V G T+R++EV+G R+P G ++ ++S D A ++ P Sbjct: 343 AAAEECLRYNGPVA-GWRRRTTREVEVEGVRLPVGANILMVVASANHDSAHFDDP----- 396 Query: 418 EHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSL 460 F D G E L F G CLG L RME+ + L Sbjct: 397 -EFFDI-GRSNASE-HLNFGYGAHQCLGRNLGRMEMQIMIEEL 436 >3EJB-B nrPDB Length = 404 Score = 42.0 bits (97), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 44/197 (22%), Positives = 74/197 (37%), Gaps = 34/197 (17%) Query: 266 QPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHP 325 P +D+ L KG + +E L AG TT ++ +L ++ HP Sbjct: 201 HPQQDMISMLL------KGREKDKLTEEEAASTCILLAIAGHETTVNLISNSVLCLLQHP 254 Query: 326 DVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQ 385 + +++ E D+IG + E R+ + + S DI++ Sbjct: 255 EQLLKLR-ENPDLIG-----------------TAVEECLRYESPTQM-TARVASEDIDIC 295 Query: 386 GFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLG 445 G I +G + L + +D +++ P F P L F G CLG Sbjct: 296 GVTIRQGEQVYLLLGAANRDPSIFTNPDVFDITR---------SPNPHLSFGHGHHVCLG 346 Query: 446 EPLARMELFLFFTSLLQ 462 LAR+E + +LLQ Sbjct: 347 SSLARLEAQIAINTLLQ 363 >2FR7-A nrPDB Length = 412 Score = 42.0 bits (97), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 42/175 (24%), Positives = 72/175 (41%), Gaps = 32/175 (18%) Query: 293 ENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAH 352 E ++V L SAG+ TT +A + + PD R++ + P + A Sbjct: 239 EEAPLLVRSLLSAGLDTTVNGIAAAVYCLARFPDEFARLRAD----------PSLARNA- 287 Query: 353 MPYTTAVIHE--VQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410 + AV E VQ F T+RD+E+ G I +G ++ L S +D W+ Sbjct: 288 --FEEAVRFESPVQTF--------FRTTTRDVELAGATIGEGEKVLMFLGSANRDPRRWD 337 Query: 411 KPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465 P R+ K + F +G C+G+ +AR+E + +L + + Sbjct: 338 DPDRYDITR---------KTSGHVGFGSGVHMCVGQLVARLEGEVVLAALARKVA 383 >3TKT-A nrPDB Length = 450 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 63/239 (26%), Positives = 92/239 (38%), Gaps = 42/239 (17%) Query: 236 LAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENL 295 +AG V F++ F L E R P D +A G P S + Sbjct: 234 VAGAVAEFERYFAG----LAAERRRN------PTDDVATVIANA-VVDGEPMSDRDTAGY 282 Query: 296 RIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPY 355 I+ A SAG TTS + A L + PD+ RV+ + + + G V + + + Sbjct: 283 YIITA---SAGHDTTSASSAGAALALARDPDLFARVKADRNLLPGIV-------EEAIRW 332 Query: 356 TTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRF 415 TT V H + D E+ G +I G L+ N + D A + +P +F Sbjct: 333 TTPVQH------------FMRTAATDTELCGQKIAAGDWLMLNYVAANHDPAQFPEPRKF 380 Query: 416 HPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPR 474 P A H L F AG CLG LAR+E+ + LL G+P+ Sbjct: 381 DPTR--PANRH-------LAFGAGSHQCLGLHLARLEMRVLLDVLLDRVDSLELAGEPK 430 >6FSH-A nrPDB Length = 398 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 47/201 (23%), Positives = 79/201 (39%), Gaps = 32/201 (15%) Query: 265 AQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILH 324 A+ +D + F+ + G+ + DE LR V L AG S + G+L ++ H Sbjct: 199 ARERKDPGDGFIGSIVAEHGD---TITDEELRGVCVQLMLAGDDNVSGMIGLGVLALLRH 255 Query: 325 PDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTS-RDIE 383 P+ Q+ DQ+ + E+ R+ VP T T+ D+ Sbjct: 256 PE--------------QIAALRGDDQS----ADRAVDELIRYL-TVPYAPTPRTAVEDVM 296 Query: 384 VQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRAC 443 V I +G T++ +L +D A+ R P + F G C Sbjct: 297 VADQVIKEGETVLCSLPMANRDRALLPDADRLDVTR---------TPVPHVAFGHGIHHC 347 Query: 444 LGEPLARMELFLFFTSLLQHF 464 LG L R++L + +T+L + F Sbjct: 348 LGAALTRLQLRIAYTALWRRF 368 >2WIO-A nrPDB Length = 431 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 57/232 (24%), Positives = 84/232 (36%), Gaps = 38/232 (16%) Query: 234 PALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDL-TEAFLAEMEKAKGNPESSFND 292 PALA ++ L E R A P DL + LAE++ + +D Sbjct: 200 PALAERIADVLNPLTAYLKARCAERR-----ADPGDDLISRLVLAEVDG------RALDD 248 Query: 293 ENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAH 352 E L AG +TT+ L + + HP + D Sbjct: 249 EEAANFSTALLLAGHITTTVLLGNIVRTLDEHPAHWDAAAE---------------DPGR 293 Query: 353 MPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKP 412 +P A++ EV R+ P + T++ EV G IP + T + S +D + P Sbjct: 294 IP---AIVEEVLRYRPPFP-QMQRTTTKATEVAGVPIPADVMVNTWVLSANRDSDAHDDP 349 Query: 413 FRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 RF P A L F G CLG PLAR+E + ++ F Sbjct: 350 DRFDPSRKSGGA-------AQLSFGHGVHFCLGAPLARLENRVALEEIIARF 394 >4TX3-A nrPDB Length = 404 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 47/201 (23%), Positives = 79/201 (39%), Gaps = 32/201 (15%) Query: 265 AQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILH 324 A+ +D + F+ + G+ + DE LR V L AG S + G+L ++ H Sbjct: 205 ARERKDPGDGFIGSIVAEHGD---TITDEELRGVCVQLMLAGDDNVSGMIGLGVLALLRH 261 Query: 325 PDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTS-RDIE 383 P+ Q+ DQ+ + E+ R+ VP T T+ D+ Sbjct: 262 PE--------------QIAALRGDDQS----ADRAVDELIRYL-TVPYAPTPRTAVEDVM 302 Query: 384 VQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRAC 443 V I +G T++ +L +D A+ R P + F G C Sbjct: 303 VADQVIKEGETVLCSLPMANRDRALLPDADRLDVTR---------TPVPHVAFGHGIHHC 353 Query: 444 LGEPLARMELFLFFTSLLQHF 464 LG L R++L + +T+L + F Sbjct: 354 LGAALTRLQLRIAYTALWRRF 374 >3A1L-A nrPDB Length = 425 Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust. Identities = 45/161 (27%), Positives = 63/161 (39%), Gaps = 28/161 (17%) Query: 302 LFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIH 361 L +AG TT+ LA +L + H DV ++ PE T A + Sbjct: 251 LLTAGHETTTNFLAKAVLTLRAHRDVLDELRTT----------PES--------TPAAVE 292 Query: 362 EVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFL 421 E+ R+ V VT DI + IP+G+ ++ L S +D P RF L Sbjct: 293 ELMRYDPPVQ-AVTRWAYEDIRLGDHDIPRGSRVVALLGSANRD------PARFPDPDVL 345 Query: 422 DAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQ 462 D E + F G CLG LAR E + +LL Sbjct: 346 DVHR---AAERQVGFGLGIHYCLGATLARAEAEIGLRALLD 383 >4Z5P-A nrPDB Length = 400 Score = 38.5 bits (88), Expect = 0.007, Method: Compositional matrix adjust. Identities = 35/130 (26%), Positives = 52/130 (40%), Gaps = 19/130 (14%) Query: 359 VIHEVQRFGDIVPLGVTHMTSR----DIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFR 414 + E+ RF VPLG +R D+E+ G + G ++ + +D ++ P R Sbjct: 273 AVEELLRF---VPLGNGVGNARIALEDVELSGGTVRAGEGVVAAAVNANRDPRAFDDPDR 329 Query: 415 FHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF---SFSVPTG 471 + L F G CLG LARMEL + LL+ F +VP Sbjct: 330 LDITR---------EKNPHLAFGHGAHYCLGAQLARMELRVAIGGLLERFPGLRLAVPAD 380 Query: 472 QPRPSHHGVF 481 Q G+F Sbjct: 381 QVEWKTGGLF 390 >4XE3-A nrPDB Length = 407 Score = 38.5 bits (88), Expect = 0.007, Method: Compositional matrix adjust. Identities = 49/231 (21%), Positives = 94/231 (40%), Gaps = 42/231 (18%) Query: 237 AGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLR 296 A ++ R Q+ F+ +D L+ + R P TE L + A N + E + Sbjct: 186 AAEIQRVQQDFMVYMDGLVAQRR------DAP---TEDLLGALALATDNDDHLTKGEIVN 236 Query: 297 IVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYT 356 + V+ L AG T+ + + L++ +R+ + + + D A +P Sbjct: 237 MGVS-LLIAGHETSVNQITNLVHLLL----TERKRYESL-----------VADPALVP-- 278 Query: 357 TAVIHEVQRFGDIVPLG-VTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE--KPF 413 A + E+ R+ +V G + + D+E+ + G + + +S +DE V++ Sbjct: 279 -AAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEEVFDHADEL 337 Query: 414 RFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 FH E + F G C+G L R+EL ++L++ F Sbjct: 338 DFHRER-----------NPHIAFGHGAHHCIGAQLGRLELQEALSALVRRF 377 >5L94-A nrPDB Length = 410 Score = 38.1 bits (87), Expect = 0.008, Method: Compositional matrix adjust. Identities = 27/106 (25%), Positives = 45/106 (42%), Gaps = 12/106 (11%) Query: 360 IHEVQRFGDIVPLGVTH-MTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418 I EV R+ P+ H + D+ + G ++ G ++ + S +D +E P F + Sbjct: 279 IEEVLRYRS--PVQALHRIVKEDVTLAGKKLKAGEHVVPWMGSAHRDAEYFEDPEVFKID 336 Query: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 KP + F G CLG PLAR+E + L+ + Sbjct: 337 R---------KPNVHMAFGRGIHFCLGAPLARIEAKIMLAELIDRY 373 >5EX6-C nrPDB Length = 434 Score = 38.1 bits (87), Expect = 0.008, Method: Compositional matrix adjust. Identities = 45/180 (25%), Positives = 74/180 (41%), Gaps = 33/180 (18%) Query: 288 SSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEM 347 + DE LR V + AG S + G+L ++ +P ++I + G V Sbjct: 255 DTVTDEELRGVCVQMMLAGDDNISGMIGLGVLALLRNP-------EQIAALRGDV----- 302 Query: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPK-GTTLITNLSSVLKDE 406 P + E+ R+ VP T T+ + G ++ K G T++ +L + +D Sbjct: 303 ------PAAERAVDELIRY-LTVPYAPTPRTAIEDSTVGDQVIKAGETVLCSLPTANRDP 355 Query: 407 AVWEKPFRFHPEHFLDAQGHFVKPEAF--LPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 A+ R V EA + F G CLG LAR+EL + +T+L + F Sbjct: 356 ALLPDADRLD-----------VTREAVPHVAFGHGVHHCLGAALARLELRIAYTALWRRF 404 >2NZA-A nrPDB Length = 413 Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust. Identities = 27/104 (25%), Positives = 42/104 (40%), Gaps = 12/104 (11%) Query: 372 LGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPE 431 +G+ + D+EV G RI G + + + +D V+ P R + P Sbjct: 294 VGLARIALEDVEVHGTRIAAGEPVYVSYLAANRDPDVFPDPDRIDLDR---------DPN 344 Query: 432 AFLPFSAGRRACLGEPLARMELFLFFTSLLQH---FSFSVPTGQ 472 L + G C G LARM+ L +LL+ +VP Q Sbjct: 345 PHLAYGNGHHFCTGAVLARMQTELLVDTLLERLPGLRLAVPAEQ 388 >6CVC-A nrPDB Length = 433 Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust. Identities = 37/172 (21%), Positives = 67/172 (38%), Gaps = 26/172 (15%) Query: 302 LFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIH 361 L AG TT ++ G+L + +PD + + + D + + Sbjct: 268 LVVAGNETTRNAISHGMLALSRYPDERAKWWSDFDGL-----------------AATAVE 310 Query: 362 EVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFL 421 E+ R+ V + + S+D++++G ++ G + S +DE + P+ F Sbjct: 311 EIVRWASPV-VYMRRTLSQDVDLRGTKMAAGDKVTLWYCSANRDEEKFADPWTFDVTRNP 369 Query: 422 DAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQP 473 + Q F G CLG LAR E+ + F L + V T +P Sbjct: 370 NPQVGF--------GGGGAHFCLGANLARREIRVVFDELRRQMPDVVATEEP 413 >4WPZ-A nrPDB Length = 397 Score = 37.7 bits (86), Expect = 0.011, Method: Compositional matrix adjust. Identities = 47/202 (23%), Positives = 87/202 (43%), Gaps = 39/202 (19%) Query: 282 AKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHP---DVQRRVQQEIDDV 338 A + +S+ + + + + SAG TT+ ++ L+ ++ +P D R ++ I Sbjct: 209 AISDGDSTLTEREIIALSIGILSAGHETTANQISMFLVTLLHNPEELDKLRDNREAIPKA 268 Query: 339 IGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRI-PKGTTLIT 397 + ++ R +P TT G I+P +T+ ++E+ G ++ P G ++ Sbjct: 269 VDELLR-------FVPLTTT--------GGIIP----RLTTAEVELSGGQVLPAGAVVLP 309 Query: 398 NLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEA--FLPFSAGRRACLGEPLARMELFL 455 +++ +D PE F D + V E L F AG CLG LAR+EL Sbjct: 310 AVATANRD-----------PEVFEDGERLNVTRENNPHLAFGAGIHHCLGAQLARIELQE 358 Query: 456 FFTSLLQ---HFSFSVPTGQPR 474 ++L +VP + R Sbjct: 359 ALGAILDRMPQVRLAVPESELR 380 >6HQD-A nrPDB Length = 420 Score = 37.7 bits (86), Expect = 0.011, Method: Compositional matrix adjust. Identities = 43/179 (24%), Positives = 75/179 (41%), Gaps = 33/179 (18%) Query: 298 VVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTT 357 +A L G TT ++++ + L+P QE D V + + Sbjct: 252 TLALLIVGGNDTTRSSMSGSAMACHLYP-------QEFDKV-----------RNNRALLA 293 Query: 358 AVIHEVQRFGDIVPLGVTHMTS-RDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFH 416 +VI EV R+ P+ T+ D+E +G +I KG ++ S +D+ V ++P F Sbjct: 294 SVIPEVVRWQ--TPIAHMRRTALEDVEFRGKQIRKGDKVVMWYLSGNRDDEVIDRPMDFI 351 Query: 417 PEHFLDAQGHFVKPEA--FLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQP 473 + +P A L F G CLG LA ++L + + + + +S G+P Sbjct: 352 AD----------RPRARHHLSFGFGIHRCLGNRLAELQLKILWEEMCERYSRIEVCGEP 400 >5FYF-A nrPDB Length = 470 Score = 37.7 bits (86), Expect = 0.011, Method: Compositional matrix adjust. Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 8/90 (8%) Query: 376 HMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLP 435 + +D+E+ G I KG ++ +S +DE ++ P +F + DA+ H + Sbjct: 359 RIAKQDVELGGQTIKKGDRVVMWYASGNRDERKFDNPDQFIIDR-KDARNH-------MS 410 Query: 436 FSAGRRACLGEPLARMELFLFFTSLLQHFS 465 F G C+G LA ++L + + +L+ F Sbjct: 411 FGYGVHRCMGNRLAELQLRILWEEILKRFD 440 >4UBS-A nrPDB Length = 393 Score = 37.7 bits (86), Expect = 0.012, Method: Compositional matrix adjust. Identities = 40/163 (24%), Positives = 66/163 (40%), Gaps = 28/163 (17%) Query: 302 LFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIH 361 L AG TT+ ++ G ++ HP+ ++ E P + MP A + Sbjct: 229 LLIAGHETTANMISLGTFTLLRHPEQLAELRAE----------PGL-----MP---AAVE 270 Query: 362 EVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFL 421 E+ RF I G+ + + DIEV G I ++ S + +D A + +P Sbjct: 271 ELLRFLSIAD-GLLRVATEDIEVAGTTIRADEGVVFATSVINRDAAGFAEP--------- 320 Query: 422 DAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 DA + F G CLG+ LAR E+ + +L + Sbjct: 321 DALDWHRSARHHVAFGFGIHQCLGQNLARAEMEIALGTLFERL 363 >1UED-A nrPDB Length = 406 Score = 37.4 bits (85), Expect = 0.014, Method: Compositional matrix adjust. Identities = 49/223 (21%), Positives = 87/223 (39%), Gaps = 47/223 (21%) Query: 246 AFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSA 305 AF LD LL R D + L + + G+ + DE L+ + L Sbjct: 198 AFNRYLDNLLARQRADPD---------DGLLGMIVRDHGD---NVTDEELKGLCTALILG 245 Query: 306 GMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVR----RPEMGDQAHMPYTTAVIH 361 G+ T + + +G+L ++ +P GQ+ PE ++ V++ Sbjct: 246 GVETVAGMIGFGVLALLDNP--------------GQIELLFESPEKAER--------VVN 283 Query: 362 EVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFL 421 E+ R+ V + +D+ + G I G ++ ++ +DEA+ P L Sbjct: 284 ELVRYLSPVQAPNPRLAIKDVVIDGQLIKAGDYVLCSILMANRDEALTPDP------DVL 337 Query: 422 DAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 DA V + F G C+G LAR L + + +L + F Sbjct: 338 DANRAAVSD---VGFGHGIHYCVGAALARSMLRMAYQTLWRRF 377 >1ODO-A nrPDB Length = 408 Score = 37.4 bits (85), Expect = 0.014, Method: Compositional matrix adjust. Identities = 54/220 (24%), Positives = 87/220 (39%), Gaps = 45/220 (20%) Query: 251 LDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTT 310 LD+L+ R T P D+T +A + +G+ + + E LR + + SAG TT Sbjct: 195 LDQLIAAKRAT-----PGDDMTSLLIAARDD-EGDGDR-LSPEELRDTLLLMISAGYETT 247 Query: 311 STTLAWGLLLMILHPD---VQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFG 367 + + ++ PD + R+ + DV+ + R E + H+P AV Sbjct: 248 VNVIDQAVHTLLTRPDQLALVRKGEVTWADVVEETLRHEPAVK-HLPLRYAVT------- 299 Query: 368 DIVPLGVTHMTSRDIEV-QGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGH 426 DI + G I +G ++ + ++ + HP+ DA Sbjct: 300 -------------DIALPDGRTIARGEPILASYAAANR-----------HPDWHEDADTF 335 Query: 427 FVKP--EAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 + L F G CLG PLARME+ L SL F Sbjct: 336 DATRTVKEHLAFGHGVHFCLGAPLARMEVTLALESLFGRF 375 >1UE8-A nrPDB Length = 367 Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust. Identities = 27/105 (25%), Positives = 46/105 (43%), Gaps = 10/105 (9%) Query: 360 IHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEH 419 + E RF V + +T ++++ I +G + ++S +DE V++ P F P+ Sbjct: 244 VEEALRFSPPV-MRTIRVTKEKVKIRDQVIDEGELVRVWIASANRDEEVFKDPDSFIPDR 302 Query: 420 FLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 P L F +G CLG PLAR+E + + F Sbjct: 303 ---------TPNPHLSFGSGIHLCLGAPLARLEARIALEEFAKKF 338 >2WM5-A nrPDB Length = 435 Score = 37.0 bits (84), Expect = 0.021, Method: Compositional matrix adjust. Identities = 39/173 (22%), Positives = 67/173 (38%), Gaps = 28/173 (16%) Query: 302 LFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIH 361 L AG TT + G+L + +P+ + R + D + + Sbjct: 271 LVVAGNETTRNAITHGVLALSRYPEQRDRWWSDFDGL-----------------APTAVE 313 Query: 362 EVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFL 421 E+ R+ V + + ++DIE++G ++ G + S +DE+ + P+ F Sbjct: 314 EIVRWASPV-VYMRRTLTQDIELRGTKMAAGDKVSLWYCSANRDESKFADPWTFDLAR-- 370 Query: 422 DAQGHFVKPEAFLPFSAG-RRACLGEPLARMELFLFFTSLLQHFSFSVPTGQP 473 P L F G CLG LAR E+ + F L + V T +P Sbjct: 371 -------NPNPHLGFGGGGAHFCLGANLARREIRVAFDELRRQMPDVVATEEP 416 >2XKR-A nrPDB Length = 398 Score = 37.0 bits (84), Expect = 0.021, Method: Compositional matrix adjust. Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 9/92 (9%) Query: 373 GVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEA 432 + + + D E G + G ++ S DEAV+ +P +F + P + Sbjct: 279 NMCRVLTADTEFHGTALCAGEKMMLLFESANFDEAVFCEPEKFDVQR---------NPNS 329 Query: 433 FLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 L F G CLG LAR+EL L +L+ Sbjct: 330 HLAFGFGTHFCLGNQLARLELSLMTERVLRRL 361 >5HDI-A nrPDB Length = 404 Score = 36.6 bits (83), Expect = 0.024, Method: Compositional matrix adjust. Identities = 46/201 (22%), Positives = 80/201 (39%), Gaps = 32/201 (15%) Query: 265 AQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILH 324 A PRD L E+ A + E + ++++ LF+AG +T+ L + ++ Sbjct: 209 AADPRD---NLLGELATACASGE--LDTLTAQVMMVTLFAAGGESTAALLGSAVWILATR 263 Query: 325 PDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV 384 PD+Q++V+ PE+ A I E R+ H+ + + Sbjct: 264 PDIQQQVRAN----------PEL--------LGAFIEETLRYEPPFRGHYRHVRNA-TTL 304 Query: 385 QGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444 G +P + L+ + +D A +E P F + +GH + F G C+ Sbjct: 305 DGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDR-AGGKGH-------ISFGKGAHFCV 356 Query: 445 GEPLARMELFLFFTSLLQHFS 465 G LAR+E + LL S Sbjct: 357 GAALARLEARIVLRLLLDRTS 377 >3WVS-A nrPDB Length = 401 Score = 36.6 bits (83), Expect = 0.029, Method: Compositional matrix adjust. Identities = 51/204 (25%), Positives = 81/204 (39%), Gaps = 39/204 (19%) Query: 265 AQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILH 324 AQP DL + + E D + +++A G TT++ + + ++ Sbjct: 206 AQPADDLISGMIEARDVQDKLTEQELLDHCIGLLIA-----GHETTASQIPSFVYALLDQ 260 Query: 325 PDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSR---- 380 P +R+ +DD PE+ + + E+ RF VPLG R Sbjct: 261 PQHWKRL---LDD-------PEL--------IPSAVEELFRF---VPLGSGSAAPRYARE 299 Query: 381 DIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGR 440 DIEV G + G ++ L + +D +E P E LD + + F G Sbjct: 300 DIEVGGTLVRAGEPVLVALGAANRDGLRFEDP----EEIKLDRPSNH-----HIGFGHGI 350 Query: 441 RACLGEPLARMELFLFFTSLLQHF 464 CLG PLAR+EL +LL+ Sbjct: 351 HHCLGAPLARLELQEALRALLERL 374 >3RWL-A nrPDB Length = 426 Score = 36.2 bits (82), Expect = 0.031, Method: Compositional matrix adjust. Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 8/85 (9%) Query: 381 DIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGR 440 D E+ G I KG ++ S +D+ V ++P F +D +P L F G Sbjct: 322 DSELGGKTIRKGDKVVMWYYSGNRDDEVIDRPEEF----IIDRP----RPRQHLSFGFGI 373 Query: 441 RACLGEPLARMELFLFFTSLLQHFS 465 C+G LA M+L + + +L FS Sbjct: 374 HRCVGNRLAEMQLRILWEEILTRFS 398 >3OFT-A nrPDB Length = 396 Score = 36.2 bits (82), Expect = 0.033, Method: Compositional matrix adjust. Identities = 52/207 (25%), Positives = 77/207 (37%), Gaps = 40/207 (19%) Query: 257 EHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAW 316 E RM AQP DL L+E G P + + R + +L G+ T + + Sbjct: 195 EKRM----AQPGDDLFSRILSE--PVGGRP---WTVDEARRMCRNLLFGGLDTVAAMIGM 245 Query: 317 GLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTH 376 L + HP+ QR +++ D + P D+ Y T + V+ Sbjct: 246 VALHLARHPEDQRLLRERPDLI------PAAADELMRRYPT--------------VAVSR 285 Query: 377 MTSRDIEVQGFRIPKGTTLITNLSSVLK--DEAVWEKPFRFHPEHFLDAQGHFVKPEAFL 434 D++ G I KG + L SVL D A +E P + L P Sbjct: 286 NAVADVDADGVTIRKGD--LVYLPSVLHNLDPASFEAPEEVRFDRGL-------APIRHT 336 Query: 435 PFSAGRRACLGEPLARMELFLFFTSLL 461 G C+G LARME+ +F L Sbjct: 337 TMGVGAHRCVGAGLARMEVIVFLREWL 363 >4PWV-A nrPDB Length = 446 Score = 36.2 bits (82), Expect = 0.036, Method: Compositional matrix adjust. Identities = 26/104 (25%), Positives = 40/104 (38%), Gaps = 9/104 (8%) Query: 381 DIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGR 440 D+E+ G I G + +S +DE V+ P+ F P + F G Sbjct: 327 DMELHGQVIAAGDVVTLWNNSANRDEEVFADPYAFDLNR---------SPNKHITFGYGP 377 Query: 441 RACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFL 484 CLG L R E+ +L + + TG+P+ H L Sbjct: 378 HFCLGAYLGRAEVHALLDALRTYTTGFEITGEPQRIHSNFLTGL 421 >4JBT-A nrPDB Length = 410 Score = 35.8 bits (81), Expect = 0.046, Method: Compositional matrix adjust. Identities = 46/203 (22%), Positives = 80/203 (39%), Gaps = 36/203 (17%) Query: 265 AQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILH 324 A+P DLT A + + E+ +E + + L +AG TT + + + ++ H Sbjct: 209 AEPGDDLTSALIYATDG-----ETPLTEEEVIGNLQALVAAGHETTVSLILTAVRALLSH 263 Query: 325 PDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV 384 P+ R V+ D IG E + + + VIH + RF + DI++ Sbjct: 264 PEQLRLVR---DGEIGW----ETAIEETLRWDGPVIHLLMRFA-----------TEDIDL 305 Query: 385 QGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEA---FLPFSAGRR 441 IP+G ++ + ++ +D V H DA + + F G Sbjct: 306 GDAVIPRGEGVVMSYRAIGRDITV----------HGADADDFDITRATAARHISFGHGPH 355 Query: 442 ACLGEPLARMELFLFFTSLLQHF 464 C G LAR+E + +L F Sbjct: 356 ICPGAALARLEAAIALPALFTRF 378 >3NC3-A nrPDB Length = 441 Score = 35.0 bits (79), Expect = 0.070, Method: Compositional matrix adjust. Identities = 37/167 (22%), Positives = 72/167 (43%), Gaps = 22/167 (13%) Query: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG 348 + +D+++ ++ ++ A TLA + ++ +P ++++DV + Sbjct: 253 ALSDKDILALILNVLLAATEPADKTLALMIYHLLNNP-------EQMNDV--------LA 297 Query: 349 DQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAV 408 D++ +P A E R+ V L + S+D V G I K T + + + +D Sbjct: 298 DRSLVPRAIA---ETLRYKPPVQL-IPRQLSQDTVVGGMEIKKDTIVFCMIGAANRDPEA 353 Query: 409 WEKP--FRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMEL 453 +E+P F H E L + F L F +G C+G A+ E+ Sbjct: 354 FEQPDVFNIHRED-LGIKSAFSGAARHLAFGSGIHNCVGTAFAKNEI 399 >5DE9-A nrPDB Length = 410 Score = 34.7 bits (78), Expect = 0.096, Method: Compositional matrix adjust. Identities = 23/91 (25%), Positives = 39/91 (42%), Gaps = 9/91 (9%) Query: 372 LGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPE 431 +G++ + D+E++G RI G + + + +D V+ P R E P Sbjct: 291 VGLSRIALEDVEIKGVRIRAGDAVYVSYLAANRDPEVFPDPDRIDFER---------SPN 341 Query: 432 AFLPFSAGRRACLGEPLARMELFLFFTSLLQ 462 + F G C G LAR+E L ++L Sbjct: 342 PHVSFGFGPHYCPGGMLARLESELLVDAVLD 372 >4MM0-A nrPDB Length = 399 Score = 34.7 bits (78), Expect = 0.096, Method: Compositional matrix adjust. Identities = 48/224 (21%), Positives = 86/224 (38%), Gaps = 43/224 (19%) Query: 244 QKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLF 303 + A + LD L+ R P DL A +A + ++ D ++R + L Sbjct: 185 RDALESYLDGLVAAKR-----ENPGSDLLSALVATAAE-----DNELTDHDVRSLSLILL 234 Query: 304 SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEV 363 AG S L +L ++ PD + ++RR D +P + + E+ Sbjct: 235 LAGYEPASNQLGSSVLTLLRFPDR-----------LAELRR----DPGLLP---SAVEEL 276 Query: 364 QRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFH---PEHF 420 R+ + +T D+ + IP + ++ + + D ++ P P++ Sbjct: 277 MRYAPAGDGALFRVTLEDVTIGDTHIPANSAVLASTQAANWDPRRFDDPTGLRLDRPDNQ 336 Query: 421 LDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 A GH G CLG LAR+EL + +LL+ F Sbjct: 337 HTALGH------------GIHFCLGAALARVELQVAIGALLRRF 368 >2UUQ-A nrPDB Length = 414 Score = 34.7 bits (78), Expect = 0.11, Method: Compositional matrix adjust. Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 10/90 (11%) Query: 373 GVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVK-PE 431 G+ T+RD+ + IP G ++ S +DE ++ P+ A+ + P Sbjct: 299 GLARTTTRDVTIGDTTIPAGRRVLLLYGSANRDER------QYGPDA---AELDVTRCPR 349 Query: 432 AFLPFSAGRRACLGEPLARMELFLFFTSLL 461 L FS G CLG ARM+ + T LL Sbjct: 350 NILTFSHGAHHCLGAAAARMQCRVALTELL 379 >1GWI-A nrPDB Length = 411 Score = 34.7 bits (78), Expect = 0.11, Method: Compositional matrix adjust. Identities = 50/232 (21%), Positives = 84/232 (36%), Gaps = 34/232 (14%) Query: 246 AFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSA 305 A LT+L ++T+ + A P DLT A + E D + + + +A Sbjct: 189 ATLTELASIMTD-TVAAKRAAPGDDLTSALIQASENG-----DHLTDAEIVSTLQLMVAA 242 Query: 306 GMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQR 365 G TT + + ++ + HP+ + V + +A +AV+ E R Sbjct: 243 GHETTISLIVNAVVNLSTHPEQRALV---------------LSGEAEW---SAVVEETLR 284 Query: 366 FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQG 425 F + + D+ V IP G LI + ++ +DE R H Sbjct: 285 FSTPTSHVLIRFAAEDVPVGDRVIPAGDALIVSYGALGRDE-------RAHGPTADRFDL 337 Query: 426 HFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQ---HFSFSVPTGQPR 474 + F G C G L+RME + +L H +VP + R Sbjct: 338 TRTSGNRHISFGHGPHVCPGAALSRMEAGVALPALYARFPHLDLAVPAAELR 389 >5GWE-A nrPDB Length = 405 Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust. Identities = 46/202 (22%), Positives = 81/202 (40%), Gaps = 46/202 (22%) Query: 290 FNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGD 349 D + ++ L AG TT+T ++ +++ HP+ + + + P++ Sbjct: 227 ITDHEIASLLYSLLFAGHETTTTLISNCFRVLLDHPEQWQAI----------LENPKL-- 274 Query: 350 QAHMPYTTAVIHEVQRF-GDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAV 408 +P A + EV R+ G IV G +D E+ G I +G ++ + S +DEA Sbjct: 275 ---IP---AAVDEVLRYSGSIV--GWRRKALKDTEIGGVAIKEGDGVLLLMGSANRDEAR 326 Query: 409 WEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLL------- 461 +E F +A+ H L F G CLG LA+++ + + Sbjct: 327 FENGEEFDISR-ANAREH-------LSFGFGIHYCLGNMLAKLQAKICLEEVTRLVPSLH 378 Query: 462 ----------QHFSFSVPTGQP 473 ++ SF VPT P Sbjct: 379 LVADKAIGFRENLSFRVPTSVP 400 >3SN5-A nrPDB Length = 491 Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust. Identities = 43/215 (20%), Positives = 82/215 (38%), Gaps = 35/215 (16%) Query: 288 SSFND-ENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVI---GQ-- 341 S+F+D E + + L+++ T T W L MI +P+ + +E+ + GQ Sbjct: 251 STFDDLEKAKTHLVVLWASQANTIPATF-WSLFQMIRNPEAMKAATEEVKRTLENAGQKV 309 Query: 342 --------VRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRD-----IEVQGFR 388 + + E+ D +P ++I E R + T+++ +E + Sbjct: 310 SLEGNPICLSQAELND---LPVLDSIIKESLRLSSA---SLNIRTAKEDFTLHLEDGSYN 363 Query: 389 IPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGH---------FVKPEAFLPFSAG 439 I K + + D ++ P F + +LD G ++PF +G Sbjct: 364 IRKDDIIALYPQLMHLDPEIYPDPLTFKYDRYLDENGKTKTTFYCNGLKLKYYYMPFGSG 423 Query: 440 RRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPR 474 C G A E+ F +L +F + GQ + Sbjct: 424 ATICPGRLFAIHEIKQFLILMLSYFELELIEGQAK 458 >5XJN-A nrPDB Length = 455 Score = 34.3 bits (77), Expect = 0.14, Method: Compositional matrix adjust. Identities = 46/202 (22%), Positives = 81/202 (40%), Gaps = 46/202 (22%) Query: 290 FNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGD 349 D + ++ L AG TT+T ++ +++ HP+ + + + P++ Sbjct: 277 ITDHEIASLLYSLLFAGHETTTTLISNCFRVLLDHPEQWQAI----------LENPKL-- 324 Query: 350 QAHMPYTTAVIHEVQRF-GDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAV 408 +P A + EV R+ G IV G +D E+ G I +G ++ + S +DEA Sbjct: 325 ---IP---AAVDEVLRYSGSIV--GWRRKALKDTEIGGVAIKEGDGVLLLMGSANRDEAR 376 Query: 409 WEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLL------- 461 +E F +A+ H L F G CLG LA+++ + + Sbjct: 377 FENGEEFDISR-ANAREH-------LSFGFGIHYCLGNMLAKLQAKICLEEVTRLVPSLH 428 Query: 462 ----------QHFSFSVPTGQP 473 ++ SF VPT P Sbjct: 429 LVADKAIGFRENLSFRVPTSVP 450 >2RCM-A nrPDB Length = 495 Score = 33.9 bits (76), Expect = 0.15, Method: Compositional matrix adjust. Identities = 36/159 (22%), Positives = 63/159 (39%), Gaps = 16/159 (10%) Query: 327 VQRRVQQEIDDVI-GQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQ 385 V R+ +EI VI MG M T +V++E RF V +D+ ++ Sbjct: 317 VHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGR-AKKDLVIE 375 Query: 386 ----GFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV--------KPEAF 433 F++ G L +D ++++ F PE F+ +G + PE Sbjct: 376 SHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETE 435 Query: 434 LPFSAGRRACLGEPLARMELFLFFTSLLQHF-SFSVPTG 471 P + G + C G+ + LF + + + SF + G Sbjct: 436 TP-TVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEVG 473 >5L1U-A nrPDB Length = 401 Score = 33.5 bits (75), Expect = 0.19, Method: Compositional matrix adjust. Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 3/56 (5%) Query: 428 VKPEAFLPFSAGRRACLGEPLARMELFLFFTSL---LQHFSFSVPTGQPRPSHHGV 480 V+P + L F G R C+G LAR+EL F L L +VP R H + Sbjct: 335 VRPRSHLAFGHGARHCIGRTLARIELTAVFERLFRRLPDLRLAVPEESLRWQEHRI 390 >6HQG-A nrPDB Length = 425 Score = 33.5 bits (75), Expect = 0.22, Method: Compositional matrix adjust. Identities = 40/174 (22%), Positives = 69/174 (39%), Gaps = 29/174 (16%) Query: 302 LFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIH 361 L G TT T++ +L + +PD R++++ + +P A++ Sbjct: 259 LIVGGNDTTRNTISGSVLALHQNPDQDRKLRE---------------NPGLIP---AMVS 300 Query: 362 EVQRFGDIVPLG-VTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHF 420 E R+ PL + RD E+ G I +G + S +DE V ++P + E Sbjct: 301 ETIRWQ--TPLAYMRRRAKRDFELGGKTIREGDKVAMWYVSGNRDEEVIDRPNDYWIER- 357 Query: 421 LDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPR 474 + L F G C+G LA ++L + + +L F G PR Sbjct: 358 -------PRVRQHLSFGFGVHRCVGNRLAELQLKIIWEEILARFPRLEVVGPPR 404 >4DO1-A nrPDB Length = 410 Score = 33.1 bits (74), Expect = 0.29, Method: Compositional matrix adjust. Identities = 38/171 (22%), Positives = 69/171 (40%), Gaps = 32/171 (18%) Query: 297 IVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYT 356 ++V L SAG+ TT + + + P +R++ + P + A + Sbjct: 241 LLVRSLLSAGLDTTVNGIGAAVYCLARFPGELQRLRSD----------PTLARNA---FE 287 Query: 357 TAVIHE--VQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFR 414 AV E VQ F T+R++E+ G I +G ++ L S +D W P Sbjct: 288 EAVRFESPVQTF--------FRTTTREVELGGAVIGEGEKVLMFLGSANRDPRRWSDP-- 337 Query: 415 FHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465 D K + F +G C+G+ +AR+E + ++L + + Sbjct: 338 -------DLYDITRKTSGHVGFGSGVHMCVGQLVARLEGEVMLSALARKVA 381 >2ZQJ-A nrPDB Length = 417 Score = 32.7 bits (73), Expect = 0.36, Method: Compositional matrix adjust. Identities = 25/112 (22%), Positives = 45/112 (40%), Gaps = 4/112 (3%) Query: 360 IHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEH 419 + EV+R+ P + + +D KGT+++ +L D +W+ P F PE Sbjct: 280 VQEVRRYYPFGPF-LGALVKKDFVWNNCEFKKGTSVLLDLYGTNHDPRLWDHPDEFRPER 338 Query: 420 FLDAQGHFVK--PEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVP 469 F + + + P+ G R C GE + + L+ + VP Sbjct: 339 FAEREENLFDMIPQGGGHAEKGHR-CPGEGITIEVMKASLDFLVHQIEYDVP 389 >5FOI-A nrPDB Length = 408 Score = 32.3 bits (72), Expect = 0.45, Method: Compositional matrix adjust. Identities = 40/163 (24%), Positives = 66/163 (40%), Gaps = 32/163 (19%) Query: 302 LFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIH 361 L +AG T++ + +L ++ HP+ ++++ PE+ MP + Sbjct: 244 LLAAGHETSANQVTLSVLTLLRHPETAAELREQ----------PEL-----MPNA---VD 285 Query: 362 EVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVW--EKPFRFHPEH 419 E+ R+ I G+ + DI + I G LI LSS D + E F H Sbjct: 286 ELLRYHSIAD-GLRRAATADIVLGDHTIRAGDGLIILLSSANHDGNTFGAEATFDIHRP- 343 Query: 420 FLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQ 462 A+ H F G CLG+ LAR+E+ + L + Sbjct: 344 ---ARHHVA-------FGYGPHQCLGQNLARLEMEVTLGKLFR 376 >4TRI-A nrPDB Length = 407 Score = 32.3 bits (72), Expect = 0.46, Method: Compositional matrix adjust. Identities = 46/210 (21%), Positives = 77/210 (36%), Gaps = 33/210 (15%) Query: 255 LTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTL 314 T+ +T A+P DL + + + + E L I++ G TT TL Sbjct: 188 FTKDVITKRRAEPTDDLFSVLVNSEVEGQRMSDDEIVFETLLILIG-----GDETTRHTL 242 Query: 315 AWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGV 374 + G ++ H D + ++D + G I E+ R+ V Sbjct: 243 SGGTEQLLRHRDQWDALVADVDLLPG------------------AIEEMLRWTSPVKNMC 284 Query: 375 THMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFL 434 +T+ D G + G ++ S DE+V+ P F + P + + Sbjct: 285 RTLTA-DTVFHGTELRAGEKIMLMFESANFDESVFGDPDNFRIDR---------NPNSHV 334 Query: 435 PFSAGRRACLGEPLARMELFLFFTSLLQHF 464 F G CLG LAR+EL L +L+ Sbjct: 335 AFGFGTHFCLGNQLARLELRLMTERVLRRL 364 >1F4U-A nrPDB Length = 368 Score = 32.3 bits (72), Expect = 0.52, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 9/64 (14%) Query: 389 IPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPL 448 I +G + ++S +DE V+ +F P+ P L F +G CLG PL Sbjct: 272 IEEGEYVRVWIASANRDEEVFHDGEKFIPDR---------NPNPHLSFGSGIHLCLGAPL 322 Query: 449 ARME 452 AR+E Sbjct: 323 ARLE 326 >5JRJ-A nrPDB Length = 351 Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust. Identities = 17/44 (38%), Positives = 23/44 (52%) Query: 195 FEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAG 238 + Y+ R + D A+ LKE RE+ N V V L +P LAG Sbjct: 298 YSYNGERIGQGKDNARNYLKEHPELAREIENKVRVALGVPELAG 341 >3OO3-A nrPDB Length = 384 Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust. Identities = 36/177 (20%), Positives = 63/177 (35%), Gaps = 32/177 (18%) Query: 288 SSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEM 347 + +DE L + + LA +LL++ HPD +++ +PE+ Sbjct: 209 AEISDEELAGLAEGNLIMAAEQMAAQLAVAVLLLVTHPDQMALLRE----------KPEL 258 Query: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407 D A EV R IV + D+ + G I G L ++ + + Sbjct: 259 IDSA--------TEEVLRHASIVEAPAPRVALADVRMAGRDIHAGDVLTCSMLATNRAPG 310 Query: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 R H + F G C+G PLAR++L + +++ F Sbjct: 311 DRFDITREKATH--------------MAFGHGIHHCIGAPLARLQLRVALPAVVGRF 353 >4Z5Q-A nrPDB Length = 423 Score = 30.4 bits (67), Expect = 1.9, Method: Compositional matrix adjust. Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 16/109 (14%) Query: 358 AVIHEVQRFGDIVPLGVTHMTSR----DIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPF 413 A + E+ RF VP ++ R D+ V G + +G +I + S+V +D V++ Sbjct: 298 AAVEELLRF---VPFAANGISPRYALEDMTVGGVLVREGEPVIVDTSAVNRDGLVFDNA- 353 Query: 414 RFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQ 462 E +D + + F G CLG LAR+EL +L++ Sbjct: 354 ---DEVVIDRADN-----RHMVFGHGAHHCLGAHLARVELQEALKALVE 394 >5Z7C-A nrPDB Length = 463 Score = 30.4 bits (67), Expect = 2.0, Method: Compositional matrix adjust. Identities = 40/172 (23%), Positives = 71/172 (41%), Gaps = 15/172 (8%) Query: 255 LTEHRMTWDPAQPPRDLTEAFLAEMEKAKG------NPESSFNDENLRIVVADLFSAGMV 308 +++ M PAQ L +A+L + A G +P ++ + E + V DL + + Sbjct: 255 ISQRVMNLPPAQAHLPLDDAYLECIVTAFGKIVDAKSPYTAGHSERV-AVYTDLIARQLA 313 Query: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEM-GDQAHMPYTTAVIHEVQRFG 367 + W +LH + V I D G++ E QAH YT +++++ F Sbjct: 314 ISDADRIWLRRAALLHDIGKLGVSNAILDKPGKLDEAEWRAVQAHAAYTEQILYKLSPFK 373 Query: 368 DIVPLGVTHMTSRDIE-----VQGFRIPKGTTLITNLSSVLKDEAVWEKPFR 414 + + H D V G I T +IT ++ + D E+P+R Sbjct: 374 TLARMAGAHHEKLDGTGYPRGVNGDEISLMTRIIT--TADIFDALSAERPYR 423 >5A01-A nrPDB Length = 710 Score = 29.3 bits (64), Expect = 3.8, Method: Compositional matrix adjust. Identities = 29/121 (23%), Positives = 53/121 (43%), Gaps = 12/121 (9%) Query: 296 RIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ-AHMP 354 RI+V D + +V T + L P V+ +EI +V+ + E+ + A +P Sbjct: 397 RIIVCDKQQSSVVDNVTVIN----ATDLSPLVENTDVKEIKEVVNAQKPVEITHKVAELP 452 Query: 355 YTTAVIH-----EVQRF--GDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407 TT ++ +VQ G +V G+ + + G +P+ + T +L D+A Sbjct: 453 NTTQIVSMIATGQVQTSLNGVVVQNGLATTQTNNKAATGEEVPQNIVITTRRQYMLPDDA 512 Query: 408 V 408 V Sbjct: 513 V 513 >5OMS-A nrPDB Length = 409 Score = 29.3 bits (64), Expect = 3.9, Method: Compositional matrix adjust. Identities = 19/87 (21%), Positives = 34/87 (39%), Gaps = 9/87 (10%) Query: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418 I E R+ + ++++ + + G +P GT ++ + S D +E P ++ Sbjct: 283 AIAEGLRWTSPIWSATARISTKPVTIAGVDLPAGTPVMLSYGSANHDTGKYEAPSQYDLH 342 Query: 419 HFLDAQGHFVKPEAFLPFSAGRRACLG 445 P L F AG AC G Sbjct: 343 R---------PPLPHLAFGAGNHACAG 360 >6HQW-A nrPDB Length = 445 Score = 29.3 bits (64), Expect = 4.0, Method: Compositional matrix adjust. Identities = 27/105 (25%), Positives = 44/105 (41%), Gaps = 15/105 (14%) Query: 359 VIHEVQRFGDIVPLGVTHMTSR-DIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHP 417 + E R+ + PL T+ D E+ G +I G +I S +DE V+E P + Sbjct: 319 AVQECIRY--VTPLAHMRRTATADTELFGNQIKAGEKVILWYISANRDETVFENPDKLMV 376 Query: 418 EHFLDAQGHFVKPEA--FLPFSAGRRACLGEPLARMELFLFFTSL 460 + +P A L F G C+G LA ++L + + Sbjct: 377 D----------RPNARRHLSFGHGIHRCVGARLAELQLRILLEEM 411 >3BUJ-A nrPDB Length = 397 Score = 29.3 bits (64), Expect = 4.0, Method: Compositional matrix adjust. Identities = 45/180 (25%), Positives = 74/180 (41%), Gaps = 30/180 (16%) Query: 273 EAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQ 332 E LA M A S N E + VV +F+ G T ++ + +L ++ HPD ++ Sbjct: 203 EDLLALMLDAHDRGLMSRN-EIVSTVVTFIFT-GHETVASQVGNAVLSLLAHPDQLDLLR 260 Query: 333 QEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKG 392 RRP++ QA + E R+ V T D+E++G R+ + Sbjct: 261 ----------RRPDLLAQA--------VEECLRYDPSVQSN-TRQLDVDVELRGRRLRRD 301 Query: 393 TTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452 ++ + +D +++P F E P + F AG R CLG LAR + Sbjct: 302 DVVVVLAGAANRDPRRYDRPDDFDIER---------DPVPSMSFGAGMRYCLGSYLARTQ 352 >3NV6-A nrPDB Length = 452 Score = 29.3 bits (64), Expect = 4.1, Method: Compositional matrix adjust. Identities = 26/107 (24%), Positives = 45/107 (42%), Gaps = 10/107 (9%) Query: 377 MTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPF 436 M ++D E +G + +G ++ + D+A +P++ LD + + F Sbjct: 342 MVAKDQEYKGVFLKRGDMILLPTALHGLDDAANPEPWK------LDFSRRSI---SHSTF 392 Query: 437 SAGRRACLGEPLARMELFLFFTSLLQHF-SFSVPTGQPRPSHHGVFA 482 G C G LARME+ + L+ FS G+ H G+ A Sbjct: 393 GGGPHRCAGMHLARMEVIVTLEEWLKRIPEFSFKEGETPIYHSGIVA 439 >4IV9-A nrPDB Length = 557 Score = 28.9 bits (63), Expect = 5.8, Method: Compositional matrix adjust. Identities = 23/96 (23%), Positives = 39/96 (40%), Gaps = 3/96 (3%) Query: 275 FLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQR---RV 331 FL + E G S R+ + +G+V + L G+ ++L+ R RV Sbjct: 19 FLKKCEMTGGIGSYSAGTPTPRVAIVGAGISGLVAATELLRAGVKDVVLYESRDRIGGRV 78 Query: 332 QQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFG 367 ++ D EMG P T + H +++FG Sbjct: 79 WSQVFDQTRPRYIAEMGAMRFPPSATGLFHYLKKFG 114 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3TBG-A nrPDB 563 e-161 2NNH-A nrPDB 548 e-156 4GQS-A nrPDB 534 e-152 5W0C-A nrPDB 533 e-152 1N6B-A nrPDB 525 e-149 4H1N-A nrPDB 509 e-144 3E6I-A nrPDB 509 e-144 2PG7-A nrPDB 482 e-136 3IBD-A nrPDB 482 e-136 5E0E-A nrPDB 481 e-136 5E58-A nrPDB 478 e-135 6B82-A nrPDB 470 e-133 3DL9-A nrPDB 434 e-122 6DWN-A nrPDB 434 e-122 4R20-A nrPDB 429 e-120 5UYS-A nrPDB 421 e-118 4R1Z-A nrPDB 416 e-116 2HI4-A nrPDB 404 e-113 6IQ5-A nrPDB 386 e-108 3QZ1-A nrPDB 380 e-106 5VBU-A nrPDB 377 e-105 5YLW-A nrPDB 358 3e-99 6DA2-A nrPDB 335 2e-92 5FSA-A nrPDB 331 4e-91 5JLC-A nrPDB 327 6e-90 4WMZ-A nrPDB 327 8e-90 5VEU-A nrPDB 322 2e-88 3L4D-A nrPDB 298 4e-81 2VE3-A nrPDB 280 1e-75 2WX2-A nrPDB 274 7e-74 6AYB-A nrPDB 268 4e-72 6CR2-A nrPDB 267 7e-72 3JUS-A nrPDB 256 1e-68 2X2N-A nrPDB 254 8e-68 3K9V-A nrPDB 239 2e-63 3MDV-A nrPDB 231 6e-61 3EL3-A nrPDB 231 8e-61 3S79-A nrPDB 229 3e-60 6C94-A nrPDB 228 6e-60 2W0A-A nrPDB 226 1e-59 3EJB-B nrPDB 199 3e-51 4KPA-A nrPDB 194 7e-50 5CJE-A nrPDB 193 1e-49 5OFQ-A nrPDB 190 1e-48 5VWS-A nrPDB 190 1e-48 3N9Z-A nrPDB 188 4e-48 2VZM-A nrPDB 187 1e-47 5IT1-A nrPDB 187 1e-47 3A50-A nrPDB 185 4e-47 3ABA-A nrPDB 184 5e-47 2Y5N-A nrPDB 182 2e-46 4OQS-A nrPDB 181 4e-46 4OQR-A nrPDB 181 6e-46 3MZS-A nrPDB 181 6e-46 4RM4-A nrPDB 178 5e-45 4GGV-A nrPDB 178 6e-45 1Z8P-A nrPDB 178 6e-45 6A7J-A nrPDB 178 6e-45 2Z36-A nrPDB 177 9e-45 5NWS-A nrPDB 176 2e-44 4YZR-A nrPDB 176 2e-44 2WIO-A nrPDB 175 3e-44 6GMF-A nrPDB 174 1e-43 6GK6-A nrPDB 173 1e-43 5YSW-A nrPDB 173 2e-43 3R9C-A nrPDB 173 2e-43 6A7I-A nrPDB 172 3e-43 5XW2-A nrPDB 172 4e-43 2ZBZ-A nrPDB 171 5e-43 5LIV-A nrPDB 171 6e-43 1EHE-A nrPDB 171 8e-43 6F88-A nrPDB 170 2e-42 5Y1I-A nrPDB 169 2e-42 5LIE-A nrPDB 169 4e-42 1CPT-A nrPDB 167 8e-42 3ABB-A nrPDB 166 2e-41 3TYW-A nrPDB 165 4e-41 3P3Z-A nrPDB 163 1e-40 4YT3-A nrPDB 162 4e-40 6B11-A nrPDB 162 4e-40 5XNT-A nrPDB 160 1e-39 5Z9I-A nrPDB 159 2e-39 6FSH-A nrPDB 159 3e-39 6M7L-A nrPDB 159 4e-39 5HIW-A nrPDB 158 6e-39 4TX3-A nrPDB 157 7e-39 4ZGX-A nrPDB 157 7e-39 1LG9-A nrPDB 157 1e-38 6M7X-A nrPDB 157 1e-38 5DQN-A nrPDB 156 1e-38 3MGX-A nrPDB 154 8e-38 6F0B-A nrPDB 154 1e-37 1Q5D-A nrPDB 149 3e-36 3IVY-A nrPDB 148 6e-36 2RFC-A nrPDB 145 4e-35 3TKT-A nrPDB 144 1e-34 5M0P-A nrPDB 142 4e-34 2FR7-A nrPDB 141 7e-34 2X9P-A nrPDB 141 1e-33 6GII-A nrPDB 138 7e-33 2IJ7-A nrPDB 132 3e-31 6FYJ-A nrPDB 129 3e-30 1WIY-A nrPDB 124 8e-29 5D3U-A nrPDB 123 2e-28 6G71-A nrPDB 122 2e-28 5YHJ-A nrPDB 116 2e-26 3AWQ-A nrPDB 104 1e-22 Sequences not found previously or not previously below threshold: 5L94-A nrPDB 189 2e-48 4UBS-A nrPDB 177 7e-45 4Z5P-A nrPDB 171 6e-43 4JBT-A nrPDB 168 6e-42 5EX6-C nrPDB 167 1e-41 3WVS-A nrPDB 163 2e-40 4WPZ-A nrPDB 162 3e-40 1GWI-A nrPDB 162 3e-40 1ODO-A nrPDB 162 4e-40 5FOI-A nrPDB 161 7e-40 4XE3-A nrPDB 159 2e-39 1UED-A nrPDB 158 4e-39 3NC3-A nrPDB 157 7e-39 5XJN-A nrPDB 155 3e-38 5GWE-A nrPDB 155 4e-38 4MM0-A nrPDB 155 4e-38 4TRI-A nrPDB 153 1e-37 4Z5Q-A nrPDB 152 3e-37 3SN5-A nrPDB 151 9e-37 2WM5-A nrPDB 151 1e-36 6CVC-A nrPDB 149 4e-36 6HQG-A nrPDB 147 1e-35 5L1U-A nrPDB 144 8e-35 3RWL-A nrPDB 143 2e-34 5FYF-A nrPDB 140 2e-33 2XKR-A nrPDB 139 2e-33 1F4U-A nrPDB 139 2e-33 3A1L-A nrPDB 139 3e-33 4DO1-A nrPDB 139 4e-33 6HQW-A nrPDB 138 6e-33 2UUQ-A nrPDB 138 6e-33 4PWV-A nrPDB 135 3e-32 1UE8-A nrPDB 135 5e-32 5HH3-A nrPDB 134 7e-32 5DE9-A nrPDB 134 1e-31 5HDI-A nrPDB 129 2e-30 5H1Z-A nrPDB 128 6e-30 6DCD-A nrPDB 128 6e-30 3OO3-A nrPDB 127 1e-29 6G5O-A nrPDB 127 2e-29 5EX8-A nrPDB 121 5e-28 3OFT-A nrPDB 121 6e-28 2WIY-A nrPDB 121 6e-28 6HQD-A nrPDB 120 1e-27 6BLD-A nrPDB 118 5e-27 4FB2-A nrPDB 117 1e-26 3WEC-A nrPDB 117 1e-26 2NZA-A nrPDB 114 9e-26 3BUJ-A nrPDB 111 6e-25 5OMS-A nrPDB 110 1e-24 5KYO-A nrPDB 108 5e-24 2QBO-A nrPDB 106 3e-23 2ZQJ-A nrPDB 104 8e-23 3NV6-A nrPDB 97 2e-20 3B98-A nrPDB 95 6e-20 4C9K-A nrPDB 91 1e-18 2IAG-A nrPDB 88 8e-18 3DBM-A nrPDB 79 4e-15 2RCM-A nrPDB 76 3e-14 2YJN-B nrPDB 58 1e-08 1PEQ-A nrPDB 37 0.016 4YXC-B nrPDB 35 0.084 4YXB-D nrPDB 32 0.45 2Z61-A nrPDB 32 0.45 3T1O-A nrPDB 31 1.0 5L9W-B nrPDB 30 3.4 3WEN-A nrPDB 29 3.8 6FOP-A nrPDB 29 4.2 1QVR-A nrPDB 29 4.3 5UE8-A nrPDB 29 4.5 4DJD-D nrPDB 29 4.6 4LJ8-A nrPDB 29 5.3 3RP9-A nrPDB 29 5.6 3OLM-A nrPDB 29 7.2 3GFZ-A nrPDB 28 9.2 >3TBG-A nrPDB Length = 479 Score = 563 bits (1451), Expect = e-161, Method: Composition-based stats. Identities = 465/475 (97%), Positives = 468/475 (98%) Query: 23 MHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLN 82 M ++ + PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLN Sbjct: 1 MAKKTSSKGKLPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLN 60 Query: 83 GLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNL 142 GLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNL Sbjct: 61 GLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNL 120 Query: 143 GLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRF 202 GLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRF Sbjct: 121 GLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRF 180 Query: 203 LRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTW 262 LRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTW Sbjct: 181 LRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTW 240 Query: 263 DPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMI 322 DPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMI Sbjct: 241 DPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMI 300 Query: 323 LHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDI 382 LHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDI Sbjct: 301 LHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDI 360 Query: 383 EVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRA 442 EVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRA Sbjct: 361 EVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRA 420 Query: 443 CLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR 497 CLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR Sbjct: 421 CLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR 475 >2NNH-A nrPDB Length = 476 Score = 548 bits (1411), Expect = e-156, Method: Composition-based stats. Identities = 196/476 (41%), Positives = 281/476 (59%), Gaps = 7/476 (1%) Query: 23 MHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLN 82 M ++ + PPGP PLP +GN+L +D ++ F + +G VF++ P+VV + Sbjct: 1 MAKKTSSKGKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFH 60 Query: 83 GLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNL 142 G AV+EAL+ +GE+ + R PI+Q + G G+ + G W+E RRFS++TLRN Sbjct: 61 GYEAVKEALIDNGEEFSGRGNSPISQRITKGL---GIISSN-GKRWKEIRRFSLTTLRNF 116 Query: 143 GLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRF 202 G+GK+S+E V EEA CL P P +L A NVI S+ +RF+Y D F Sbjct: 117 GMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNF 176 Query: 203 LRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAGKVLRFQKAFLTQLDELLTEHRMT 261 L L+ E + + +V N P+L+ P KVL+ + + E + EH+ + Sbjct: 177 LTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQAS 236 Query: 262 WDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLM 321 D PRD + FL +ME+ K N +S FN ENL VADLF AG TTSTTL +GLLL+ Sbjct: 237 LD-VNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLL 295 Query: 322 ILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRD 381 + HP+V +VQ+EID VIG+ R P M D++HMPYT AV+HE+QR+ D+VP GV H + D Sbjct: 296 LKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTD 355 Query: 382 IEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRR 441 + + + IPKGTT++ L+SVL D+ + P F P HFLD G+F K + F+PFSAG+R Sbjct: 356 TKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKR 415 Query: 442 ACLGEPLARMELFLFFTSLLQHFSFSVPTG-QPRPSHHGVFAFLVSPSPYELCAVP 496 C GE LARMELFLF T++LQ+F+ + + + P Y++C +P Sbjct: 416 ICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIP 471 >4GQS-A nrPDB Length = 477 Score = 534 bits (1375), Expect = e-152, Method: Composition-based stats. Identities = 191/477 (40%), Positives = 278/477 (58%), Gaps = 8/477 (1%) Query: 23 MHRRQRWA-ARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVL 81 M ++ + PPGP PLP +GN+L +D ++ L + +G VF+L +VVL Sbjct: 1 MAKKTSSGRGKLPPGPTPLPVIGNILQIDIKDVSKSLTNLSKIYGPVFTLYFGLERMVVL 60 Query: 82 NGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRN 141 +G V+EAL+ GE+ + R P+ + G G+ + G W+E RRFS+ TLRN Sbjct: 61 HGYEVVKEALIDLGEEFSGRGHFPLAERANRGF---GIVFSN-GKRWKEIRRFSLMTLRN 116 Query: 142 LGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPR 201 G+GK+S+E V EEA CL P P +L A NVI S+ +RF+Y D + Sbjct: 117 FGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQ 176 Query: 202 FLRLLDLAQEGLKEESGFLREVLNAVP-VLLHIPALAGKVLRFQKAFLTQLDELLTEHRM 260 FL L++ E ++ S ++ N P ++ + P K+L+ + + E + EH+ Sbjct: 177 FLNLMEKLNENIRIVSTPWIQICNNFPTIIDYFPGTHNKLLKNLAFMESDILEKVKEHQE 236 Query: 261 TWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLL 320 + D PRD + FL +MEK K N +S F ENL I ADL AG TTSTTL + LLL Sbjct: 237 SMDI-NNPRDFIDCFLIKMEKEKQNQQSEFTIENLVITAADLLGAGTETTSTTLRYALLL 295 Query: 321 MILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSR 380 ++ HP+V +VQ+EI+ V+G+ R P M D+ HMPYT AV+HEVQR+ D++P + H + Sbjct: 296 LLKHPEVTAKVQEEIERVVGRNRSPCMQDRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTC 355 Query: 381 DIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGR 440 D++ + + IPKGTT++T+L+SVL D + P F P HFLD G+F K F+PFSAG+ Sbjct: 356 DVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGK 415 Query: 441 RACLGEPLARMELFLFFTSLLQHFSF-SVPTGQPRPSHHGVFAFLVSPSPYELCAVP 496 R C+GE LARMELFLF T +LQ+F+ S+ + + V F P Y+LC +P Sbjct: 416 RICVGEGLARMELFLFLTFILQNFNLKSLIDPKDLDTTPVVNGFASVPPFYQLCFIP 472 >5W0C-A nrPDB Length = 477 Score = 533 bits (1373), Expect = e-152, Method: Composition-based stats. Identities = 191/477 (40%), Positives = 278/477 (58%), Gaps = 8/477 (1%) Query: 23 MHRRQRWA-ARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVL 81 M ++ + PPGP PLP +GN+L + ++ L + +G VF+L P+VVL Sbjct: 1 MAKKTSSGRGKLPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVL 60 Query: 82 NGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRN 141 +G AV+EAL+ GE+ + R P+ + G G+ + G W+E RRFS+ TLRN Sbjct: 61 HGYEAVKEALIDLGEEFSGRGIFPLAERANRGF---GIVFSN-GKKWKEIRRFSLMTLRN 116 Query: 142 LGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPR 201 G+GK+S+E V EEA CL P P +L A NVI S+ +RF+Y D + Sbjct: 117 FGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQ 176 Query: 202 FLRLLDLAQEGLKEESGFLREVLNAV-PVLLHIPALAGKVLRFQKAFLTQLDELLTEHRM 260 FL L++ E +K S ++ N P++ + P K+L+ + + E + EH+ Sbjct: 177 FLNLMEKLNENIKILSSPWIQICNNFSPIIDYFPGTHNKLLKNVAFMKSYILEKVKEHQE 236 Query: 261 TWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLL 320 + D P+D + FL +MEK K N S F E+L DLF AG TTSTTL + LLL Sbjct: 237 SMD-MNNPQDFIDCFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTSTTLRYALLL 295 Query: 321 MILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSR 380 ++ HP+V +VQ+EI+ VIG+ R P M D++HMPYT AV+HEVQR+ D++P + H + Sbjct: 296 LLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTC 355 Query: 381 DIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGR 440 DI+ + + IPKGTT++ +L+SVL D + P F P HFLD G+F K + F+PFSAG+ Sbjct: 356 DIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGK 415 Query: 441 RACLGEPLARMELFLFFTSLLQHFSF-SVPTGQPRPSHHGVFAFLVSPSPYELCAVP 496 R C+GE LA MELFLF TS+LQ+F+ S+ + + V F P Y+LC +P Sbjct: 416 RICVGEALAGMELFLFLTSILQNFNLKSLVDPKNLDTTPVVNGFASVPPFYQLCFIP 472 >1N6B-A nrPDB Length = 473 Score = 525 bits (1352), Expect = e-149, Method: Composition-based stats. Identities = 195/476 (40%), Positives = 275/476 (57%), Gaps = 10/476 (2%) Query: 23 MHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLN 82 M ++ + PPGP P P +GN+L +D ++ + +G VF++ L P VVL+ Sbjct: 1 MAKKTSSKGKLPPGPTPFPIIGNILQIDAKDISKSLTKFSECYGPVFTVYLGMKPTVVLH 60 Query: 83 GLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNL 142 G AV+EALV GE+ A R VPI + + G G+ + W+E RRFS+ TLRN Sbjct: 61 GYEAVKEALVDLGEEFAGRGSVPILEKVSKGL---GIAFSN-AKTWKEMRRFSLMTLRNF 116 Query: 143 GLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRF 202 G+GK+S+E + EEA CL + P P +L A NVI S+ RF+Y D F Sbjct: 117 GMGKRSIEDRIQEEARCLVEELRKTNASPCDPTFILGCAPCNVICSVIFHNRFDYKDEEF 176 Query: 203 LRLLDLAQEGLKEESGFLREVLNAVPVLL-HIPALAGKVLRFQKAFLTQLDELLTEHRMT 261 L+L++ E ++ +V N P LL + P + +L+ + E + EH+ Sbjct: 177 LKLMESLHENVELLGTPWLQVYNNFPALLDYFPGIHKTLLKNADYIKNFIMEKVKEHQKL 236 Query: 262 WDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLM 321 D PRD + FL +ME+ F E+L I V+DLF AG TTSTTL + LLL+ Sbjct: 237 LD-VNNPRDFIDCFLIKMEQ---ENNLEFTLESLVIAVSDLFGAGTETTSTTLRYSLLLL 292 Query: 322 ILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRD 381 + HP+V RVQ+EI+ VIG+ R P M D++ MPYT AVIHE+QRF D++P + H +RD Sbjct: 293 LKHPEVAARVQEEIERVIGRHRSPCMQDRSRMPYTDAVIHEIQRFIDLLPTNLPHAVTRD 352 Query: 382 IEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRR 441 + + + IPKGT +IT+L+SVL DE + P F P HFLD G+F K + F+PFSAG+R Sbjct: 353 VRFRNYFIPKGTDIITSLTSVLHDEKAFPNPKVFDPGHFLDESGNFKKSDYFMPFSAGKR 412 Query: 442 ACLGEPLARMELFLFFTSLLQHFSF-SVPTGQPRPSHHGVFAFLVSPSPYELCAVP 496 C+GE LARMELFLF TS+LQ+F S+ + V F+ P Y+LC +P Sbjct: 413 MCVGEGLARMELFLFLTSILQNFKLQSLVEPKDLDITAVVNGFVSVPPSYQLCFIP 468 >4H1N-A nrPDB Length = 479 Score = 509 bits (1310), Expect = e-144, Method: Composition-based stats. Identities = 198/477 (41%), Positives = 273/477 (57%), Gaps = 7/477 (1%) Query: 23 MHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLN 82 M ++ + PPGP PLP LGNLL +D + F +LR ++GDVF++ L PVVVL Sbjct: 1 MAKKTSSKGKLPPGPSPLPVLGNLLQMDRKGLLRSFLRLREKYGDVFTVYLGSRPVVVLC 60 Query: 83 GLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNL 142 G A+REALV E + R + + + G GV A G WR RRFS++T+R+ Sbjct: 61 GTDAIREALVDQAEAFSGRGKIAVVDPIFQG---YGVIFAN-GERWRALRRFSLATMRDF 116 Query: 143 GLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRF 202 G+GK+S+E+ + EEA CL G L SN+I S+ G+RF+Y DP F Sbjct: 117 GMGKRSVEERIQEEARCLVEELRKSKGALLDNTLLFHSITSNIICSIVFGKRFDYKDPVF 176 Query: 203 LRLLDLAQEGLKEESGFLREVLNAVPVLL-HIPALAGKVLRFQKAFLTQLDELLTEHRMT 261 LRLLDL + S F +V L + P ++ R + T + + + +HR T Sbjct: 177 LRLLDLFFQSFSLISSFSSQVFELFSGFLKYFPGTHRQIYRNLQEINTFIGQSVEKHRAT 236 Query: 262 WDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLM 321 DP+ P RD + +L MEK K +P S F+ +NL + V LF+AG TTSTTL +G LLM Sbjct: 237 LDPSNP-RDFIDVYLLRMEKDKSDPSSEFHHQNLILTVLSLFAAGTETTSTTLRYGFLLM 295 Query: 322 ILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRD 381 + +P V RVQ+EI+ VIG R P + D+A MPYT AVIHE+QR GD++P GV H ++D Sbjct: 296 LKYPHVTERVQKEIEQVIGSHRPPALDDRAKMPYTDAVIHEIQRLGDLIPFGVPHTVTKD 355 Query: 382 IEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRR 441 + +G+ IPK T + LSS L D +E P F+P HFLDA G + E F+PFS G+R Sbjct: 356 TQFRGYVIPKNTEVFPVLSSALHDPRYFETPNTFNPGHFLDANGALKRNEGFMPFSLGKR 415 Query: 442 ACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGV-FAFLVSPSPYELCAVPR 497 CLGE +AR ELFLFFT++LQ+FS + P P Y++ + R Sbjct: 416 ICLGEGIARTELFLFFTTILQNFSIASPVPPEDIDLTPRESGVGNVPPSYQIRFLAR 472 >3E6I-A nrPDB Length = 476 Score = 509 bits (1310), Expect = e-144, Method: Composition-based stats. Identities = 185/477 (38%), Positives = 270/477 (56%), Gaps = 8/477 (1%) Query: 23 MHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLN 82 M ++ + PPGP PLP +GNL ++ +N P F +L +RFG VF+L + +VV++ Sbjct: 1 MAKKTSSKGKLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 60 Query: 83 GLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNL 142 G AV+EAL+ + ++ + R +P R +G+ GP W++ RRFS++TLRN Sbjct: 61 GYKAVKEALLDYKDEFSGRGDLPAFH----AHRDRGIIF-NNGPTWKDIRRFSLTTLRNY 115 Query: 143 GLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRF 202 G+GK+ E + EA L A G+PF P L+ A NVIA + + F+Y+D +F Sbjct: 116 GMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKF 175 Query: 203 LRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAGKVLRFQKAFLTQLDELLTEHRMT 261 LRL+ L E S ++ N P LH +P KV++ + E + EH + Sbjct: 176 LRLMYLFNENFHLLSTPWLQLYNNFPSFLHYLPGSHRKVIKNVAEVKEYVSERVKEHHQS 235 Query: 262 WDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLM 321 DP PRDLT+ L EMEK K + E + + + + VADLF AG TTSTTL +GLL++ Sbjct: 236 LDP-NCPRDLTDCLLVEMEKEKHSAERLYTMDGITVTVADLFFAGTETTSTTLRYGLLIL 294 Query: 322 ILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRD 381 + +P+++ ++ +EID VIG R P + D+ MPY AV+HE+QRF +VP + H +RD Sbjct: 295 MKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRD 354 Query: 382 IEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRR 441 +G+ IPKGT ++ L SVL D + P +F PEHFL+ G F + F PFS G+R Sbjct: 355 TIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFSTGKR 414 Query: 442 ACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGV-FAFLVSPSPYELCAVPR 497 C GE LARMELFL ++LQHF+ + F P Y+LC +PR Sbjct: 415 VCAGEGLARMELFLLLCAILQHFNLKPLVDPKDIDLSPIHIGFGCIPPRYKLCVIPR 471 >2PG7-A nrPDB Length = 476 Score = 482 bits (1240), Expect = e-136, Method: Composition-based stats. Identities = 172/477 (36%), Positives = 262/477 (54%), Gaps = 7/477 (1%) Query: 23 MHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLN 82 M ++ + PPGP PLP +GN L ++ + ++ R+G VF++ L VVVL Sbjct: 1 MAKKTSSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 60 Query: 83 GLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNL 142 G AVREALV E+ + R + + GV + G ++ RRFS++TLR+ Sbjct: 61 GHDAVREALVDQAEEFSGRGEQATFD---WVFKGYGVVFSN-GERAKQLRRFSIATLRDF 116 Query: 143 GLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRF 202 G+GK+ +E+ + EEA L A G P L + VSNVI+S+ G RF+Y D F Sbjct: 117 GVGKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEF 176 Query: 203 LRLLDLAQEGLKEESGFLREVLNAVP-VLLHIPALAGKVLRFQKAFLTQLDELLTEHRMT 261 L LL + + S ++ V+ H+P + + + + + + ++ T Sbjct: 177 LSLLRMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQLLQGLEDFIAKKVEHNQRT 236 Query: 262 WDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLM 321 DP PRD ++FL M++ + NP + F +NL + LF G T STTL +G LL+ Sbjct: 237 LDP-NSPRDFIDSFLIRMQEEEKNPNTEFYLKNLVMTTLQLFVGGTETVSTTLRYGFLLL 295 Query: 322 ILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRD 381 + HP+V+ +V +EID VIG+ R+P+ D+A MPY AVIHE+QRFGD++P+ + +D Sbjct: 296 MKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKD 355 Query: 382 IEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRR 441 + + F +PKGT + L SVL+D + + P F+P+HFL+ +G F K +AF+PFS G+R Sbjct: 356 TKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKR 415 Query: 442 ACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGV-FAFLVSPSPYELCAVPR 497 C GE LARMELFLFFT+++Q+F F P Y + +PR Sbjct: 416 NCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDIDVSPKHVGFATIPRNYTMSFLPR 472 >3IBD-A nrPDB Length = 476 Score = 482 bits (1240), Expect = e-136, Method: Composition-based stats. Identities = 191/477 (40%), Positives = 270/477 (56%), Gaps = 7/477 (1%) Query: 23 MHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLN 82 M ++ + PPGP PLP LGNLL +D + F + R ++GDVF++ L PVV+L Sbjct: 1 MAKKTSSKGKLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDVFTVHLGPRPVVMLC 60 Query: 83 GLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNL 142 G+ A+REALV E + R + + G GV A G W+ RRFSV+T+R+ Sbjct: 61 GVEAIREALVDKAEAFSGRGKIAMVDPFFRG---YGVIFAN-GNRWKVLRRFSVTTMRDF 116 Query: 143 GLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRF 202 G+GK+S+E+ + EEA CL G P L +N+I S+ G+RF Y D F Sbjct: 117 GMGKRSVEERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEF 176 Query: 203 LRLLDLAQEGLKEESGFLREVLNAVPVLL-HIPALAGKVLRFQKAFLTQLDELLTEHRMT 261 L++L+L + S ++ L H P +V + + + + +HR T Sbjct: 177 LKMLNLFYQTFSLISSVFGQLFELFSGFLKHFPGAHRQVYKNLQEINAYIGHSVEKHRET 236 Query: 262 WDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLM 321 DP+ PRDL + +L MEK K N S F+ +NL + LF AG TTSTTL +G LLM Sbjct: 237 LDPS-APRDLIDTYLLHMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLM 295 Query: 322 ILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRD 381 + +P V RV +EI+ VIG R PE+ D+A MPYT AVI+E+QRF D++P+GV H+ ++ Sbjct: 296 LKYPHVAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQH 355 Query: 382 IEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRR 441 +G+ IPK T + LS+ L D +EKP F+P+HFLDA G K EAF+PFS G+R Sbjct: 356 TSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSLGKR 415 Query: 442 ACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGV-FAFLVSPSPYELCAVPR 497 CLGE +AR ELFLFFT++LQ+FS + P P Y++ +PR Sbjct: 416 ICLGEGIARAELFLFFTTILQNFSMASPVAPEDIDLTPQECGVGKIPPTYQIRFLPR 472 >5E0E-A nrPDB Length = 463 Score = 481 bits (1239), Expect = e-136, Method: Composition-based stats. Identities = 186/455 (40%), Positives = 262/455 (57%), Gaps = 7/455 (1%) Query: 45 NLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPV 104 NLL +D F ++R ++GDVF++ L PVV+L G A+REALV E + R + Sbjct: 14 NLLQMDRGGFLNSFRRIREKYGDVFTVHLGPRPVVMLYGTEAIREALVDQAEAFSGRGTI 73 Query: 105 PITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAF 164 + + + G GV A G W+ RRFS+ T+R+ G+GK+S+E+ + EEA CL F Sbjct: 74 AVVEPIFRG---YGVVFAN-GERWKALRRFSLVTMRDFGMGKRSVEERIQEEARCLVEEF 129 Query: 165 ANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVL 224 G P P L +N+I S+ G RF+Y D +FLRLL L + S F +V Sbjct: 130 RKSQGAPLDPTFLFQCITANIICSIVFGERFDYKDHQFLRLLYLFYQSFSLISSFSSQVF 189 Query: 225 NAVPVLL-HIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAK 283 L + P ++ R + L + + + +HR T DP+ P RD + +L MEK K Sbjct: 190 ELFSGFLKYFPGTHRQISRNLQEILDYIGQSVEKHRATLDPSHP-RDFIDTYLLRMEKEK 248 Query: 284 GNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVR 343 N + F+ +NL I V LF AG T+STTL +G LLM+ +P V +VQ+EID VIG R Sbjct: 249 SNQHTEFDHQNLVISVLSLFFAGTETSSTTLRYGFLLMLKYPHVAEKVQKEIDQVIGSHR 308 Query: 344 RPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVL 403 P + D+ MPYT AVI+E+QRF D++P+GV H ++D +G+ +PK T + LSS L Sbjct: 309 LPTLEDRTKMPYTEAVIYEIQRFSDLIPIGVPHKVTKDTLFRGYLLPKNTEVYPILSSAL 368 Query: 404 KDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQH 463 D +E+P F+P+HFLDA G K EAF+PFS G+R CLGE +AR ELFLFFT++LQ+ Sbjct: 369 HDPQYFEQPDTFNPDHFLDANGALKKSEAFMPFSIGKRICLGEGIARNELFLFFTTILQN 428 Query: 464 FSFSVPTGQPRPSHHGV-FAFLVSPSPYELCAVPR 497 FS S P F P Y++C + R Sbjct: 429 FSLSSPVAPKDIDLSPKESGFGKVPQTYQICFLAR 463 >5E58-A nrPDB Length = 493 Score = 478 bits (1230), Expect = e-135, Method: Composition-based stats. Identities = 179/455 (39%), Positives = 256/455 (56%), Gaps = 7/455 (1%) Query: 45 NLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPV 104 NLL +D F ++R ++GDVF++ L PVV+L G A+REALV E + R + Sbjct: 42 NLLQMDRGGFLNSFMRIREKYGDVFTVHLGPRPVVMLYGTEAIREALVDQAEAFSGRGTI 101 Query: 105 PITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAF 164 + + + G+ + G W+ RRFS++T+R+ G+GK+S+E + EEA CL Sbjct: 102 AVIKPVIGD---YGMIFSN-GERWKVLRRFSLATMRDFGMGKRSVEDRIQEEAQCLVEEL 157 Query: 165 ANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVL 224 G P P L +N+I S+ G R++Y D +FLRLLDL S F +V Sbjct: 158 QKSQGAPLDPTFLFQCITANIICSIVFGERYDYKDRQFLRLLDLFYRTFSLMSSFSSQVF 217 Query: 225 NAVPVLL-HIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAK 283 + + P ++ R + L + + + +HR T DP+ P RD + +L MEK K Sbjct: 218 ELFSGFMKYFPGAHRQITRNLQEILDYVGQSVEKHRATLDPSNP-RDFIDTYLLRMEKEK 276 Query: 284 GNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVR 343 N + F+ +NL I V LF AG TTSTTL +G LLM+ +P V +VQ+EID VIG R Sbjct: 277 SNQHTEFHHQNLLISVLSLFFAGTETTSTTLRYGFLLMLKYPHVAEKVQKEIDQVIGSHR 336 Query: 344 RPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVL 403 P + D+ MPYT AVIHE+QRF D+ P+G H ++D +G+ +PK T + LSS L Sbjct: 337 LPTLEDRTKMPYTDAVIHEIQRFSDLAPIGAPHKVTKDTLFRGYLLPKNTEVYPILSSAL 396 Query: 404 KDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQH 463 D +E+P F+P+HFLDA G K EAF+PFS G+R CLGE +AR ELFLFFT++LQ+ Sbjct: 397 HDPQYFEQPGTFNPDHFLDANGALKKSEAFMPFSIGKRICLGEGIARNELFLFFTTILQN 456 Query: 464 FSF-SVPTGQPRPSHHGVFAFLVSPSPYELCAVPR 497 FS S + P Y++ + R Sbjct: 457 FSVSSSVAPKDIDLSPKESGIGKVPQTYQISFLAR 491 >6B82-A nrPDB Length = 509 Score = 470 bits (1209), Expect = e-133, Method: Composition-based stats. Identities = 139/495 (28%), Positives = 241/495 (48%), Gaps = 24/495 (4%) Query: 23 MHRRQRWAAR-------------YPPGPLPLPGLGNLLHVDFQNTPY-CFDQLRRRFGDV 68 M ++ + PP LP +G+L+ + + P+ F L++++GD+ Sbjct: 1 MAKKTSSKGKKQKMNGFVPAGNRSPPSLPSLPIIGSLMSLVSDSPPHIFFQDLQKKYGDL 60 Query: 69 FSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAW 128 +SL + ++++N +E L+ G+ A RP T +L + + A Y W Sbjct: 61 YSLMMGSHKLLIVNNHHHAKEILIKKGKIFAGRPRTVTTDLLTRD--GKDIAFADYSSTW 118 Query: 129 REQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIAS 188 + R+ L G G S+E+ + EA+ +C L +AV+NV+ + Sbjct: 119 KFHRKMVHGALCMFGEGSVSIEKIICREASSMCEVLTESQNSAVDLGPELTRAVTNVVCA 178 Query: 189 LTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFL 248 L ++ D F +L +Q + + +++ P L P ++LR + Sbjct: 179 LCFNSSYKRGDAEFESMLQYSQGIVDTVA--KDSLVDIFPWLQIFPNKDLRILRQCISIR 236 Query: 249 TQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESS----FNDENLRIVVADLFS 304 +L + E RDL +A L ++ N S+ ++++ + V ++F Sbjct: 237 DKLLQKKYEEHKVTYSDNVQRDLLDALLRAKRSSENNNSSTRDVGLTEDHVLMTVGEIFG 296 Query: 305 AGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQ 364 AG+ TT+TTL W + ++ +P VQR++Q+E+D IG+ R P++ D+ ++PY A I EV Sbjct: 297 AGVETTTTTLKWSIAYLVHNPQVQRKIQEELDSKIGKERHPQLSDRGNLPYLEATICEVM 356 Query: 365 RFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQ 424 R + PL + H+ +D V + + KGT ++ N+ S+ DE W+ P F P FL+ + Sbjct: 357 RIRPVSPLLIPHVALQDSSVGEYTVQKGTRVVINMWSLHHDEKEWKNPELFDPGRFLNEE 416 Query: 425 GHF--VKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFA 482 G ++LPF AG R CLGE LA+MELFLF +LQ F+ +PTGQP P G F Sbjct: 417 GDGLCCPSGSYLPFGAGVRVCLGEALAKMELFLFLAWILQRFTLEMPTGQPLPDLQGKFG 476 Query: 483 FLVSPSPYELCAVPR 497 ++ P +++ A R Sbjct: 477 VVLQPKKFKVVAKVR 491 >3DL9-A nrPDB Length = 479 Score = 434 bits (1116), Expect = e-122, Method: Composition-based stats. Identities = 178/444 (40%), Positives = 246/444 (55%), Gaps = 4/444 (0%) Query: 54 TPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFG 113 + + +G++FSL L VVLNG V+E LV E ADRP +P+ + Sbjct: 36 PHVYMRKQSQVYGEIFSLDLGGISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMT-- 93 Query: 114 PRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFR 173 + G+ +RYG W + RR +V++ R G G+KS E + EE A + GRPF Sbjct: 94 -KMGGLLNSRYGRGWVDHRRLAVNSFRYFGYGQKSFESKILEETKFFNDAIETYKGRPFD 152 Query: 174 PNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHI 233 L+ AVSN+ + G RF Y+D F +++L E ++ + + NA P + + Sbjct: 153 FKQLITNAVSNITNLIIFGERFTYEDTDFQHMIELFSENVELAASASVFLYNAFPWIGIL 212 Query: 234 PALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDE 293 P + L A + L E Q P+ +A+L EM++ K +P S+F+ E Sbjct: 213 PFGKHQQLFRNAAVVYDFLSRLIEKASVNRKPQLPQHFVDAYLDEMDQGKNDPSSTFSKE 272 Query: 294 NLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHM 353 NL V +L AG TT+ L W +L M L+P++Q +VQ+EID ++G +P D+ M Sbjct: 273 NLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCKM 332 Query: 354 PYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPF 413 PYT AV+HEV RF +IVPLG+ H TS D V+G+ IPKGTT+ITNL SV DE W P Sbjct: 333 PYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPE 392 Query: 414 RFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQP 473 FHPE FLD+ G+F K EA +PFS GRR CLGE LARME+FLFFT+LLQ F P + Sbjct: 393 VFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHFP-HEL 451 Query: 474 RPSHHGVFAFLVSPSPYELCAVPR 497 P + P PY +CA R Sbjct: 452 VPDLKPRLGMTLQPQPYLICAERR 475 >6DWN-A nrPDB Length = 491 Score = 434 bits (1115), Expect = e-122, Method: Composition-based stats. Identities = 143/464 (30%), Positives = 242/464 (52%), Gaps = 21/464 (4%) Query: 23 MHRRQRWAA-RYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVL 81 M ++ + PPGP P +G++L + +N ++ +++GDV +++ TPVVVL Sbjct: 1 MAKKTSSKGLKNPPGPWGWPLIGHMLTLG-KNPHLALSRMSQQYGDVLQIRIGSTPVVVL 59 Query: 82 NGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRN 141 +GL +R+ALV G+D RP + ++ G F GP W +RR + + L++ Sbjct: 60 SGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMS--FSPDSGPVWAARRRLAQNGLKS 117 Query: 142 LGLGKK-------SLEQWVTEEAACLCAAFANHSGRP--FRPNGLLDKAVSNVIASLTCG 192 + LE+ V++EA L + P F P + +V+NVI ++ G Sbjct: 118 FSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFG 177 Query: 193 RRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRF-QKAFLTQL 251 RR++++ L L++L + + +P+L ++P + + + F + + Sbjct: 178 RRYDHNHQELLSLVNLNNNFGEVVGS--GNPADFIPILRYLPNPSLNAFKDLNEKFYSFM 235 Query: 252 DELLTEHRMTWDPAQPPRDLTEAFLAEMEKA--KGNPESSFNDENLRIVVADLFSAGMVT 309 +++ EH T++ RD+T++ + ++ N +DE + +V DLF AG T Sbjct: 236 QKMVKEHYKTFEKGHI-RDITDSLIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDT 294 Query: 310 TSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDI 369 +T ++W L+ ++++P VQR++Q+E+D VIG+ RRP + D++H+PY A I E R Sbjct: 295 VTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSF 354 Query: 370 VPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVK 429 VP + H T+RD ++GF IPKG + N + D+ +W P F PE FL G K Sbjct: 355 VPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDK 414 Query: 430 --PEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTG 471 E + F G+R C+GE +AR E+FLF LLQ FSVP G Sbjct: 415 VLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFSVPLG 458 >4R20-A nrPDB Length = 486 Score = 429 bits (1102), Expect = e-120, Method: Composition-based stats. Identities = 146/490 (29%), Positives = 234/490 (47%), Gaps = 26/490 (5%) Query: 23 MHRRQRWAAR---------YPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQL 73 M ++ + +P P L F QL ++G +F L Sbjct: 1 MAKKTSSKGKEGVGSSSVSFPCLPRLPLLGSLLHLRSNLPPHLLFTQLSSQYGPLFGLYA 60 Query: 74 AWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRR 133 +V++ + VRE L+ G + A RP + T +L G + + A Y P W+ RR Sbjct: 61 GPHLTLVVSEIGLVREVLLQRGREFAGRPKMVTTDLLTQG--GKDIAFADYSPLWKNHRR 118 Query: 134 FSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGR 193 S+ G G L+ V E A LC G+ + +L +AV+NVI L Sbjct: 119 LVHSSFTLFGEGSNKLQTIVQEAADSLCEELQACRGQSSDLSVVLMRAVTNVICRLVFSS 178 Query: 194 RFEYDDPRFLRLLDLAQEGLKEESGFLREVLNA--VPVLLHIPALAGKVLRFQKAFLTQL 251 ++ DP Q ++ G ++ + V + + K L+ K ++ Sbjct: 179 SYQPSDPEL-------QTVIQYNDGIVQTIARGGLVDIFPWLRIFPNKDLKRLKECVSIR 231 Query: 252 DELL----TEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGM 307 D+LL EH+ + P +P RDL +A L ++ G + ++++ + A+ F AG+ Sbjct: 232 DQLLYKKLLEHKKSLTPGEP-RDLLDALLIGQQRGSGGADD-ITEDHVLMTAAEAFGAGV 289 Query: 308 VTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFG 367 TTSTTL W + ++ HP +Q RVQ E+D+ +G R P + D+ H+P AV+ EV R Sbjct: 290 ETTSTTLLWTIAFLLHHPQLQERVQAELDECVGVDRPPCLSDRPHLPLLDAVLCEVMRIR 349 Query: 368 DIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHF 427 + P+ + H+ +D + G +PKGT ++ N+ ++ D W++P +F+PE FL+ G Sbjct: 350 PVSPILIPHVAMQDTSLGGHSVPKGTRVLVNMWAIHHDPKHWDQPEQFNPERFLEPSGKK 409 Query: 428 VKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSP 487 +FLPF AG R C+GE LAR+ELFLF + LQ FSFS P+ P G F ++ P Sbjct: 410 KTQSSFLPFGAGPRVCVGESLARIELFLFVSRPLQRFSFSCPSEASLPDLQGRFGVVLQP 469 Query: 488 SPYELCAVPR 497 Y + PR Sbjct: 470 ERYTVTVTPR 479 >5UYS-A nrPDB Length = 494 Score = 421 bits (1083), Expect = e-118, Method: Composition-based stats. Identities = 126/484 (26%), Positives = 230/484 (47%), Gaps = 15/484 (3%) Query: 23 MHRRQRWAARYPPGPLPLPGLGNLLHVDF-QNTPYCFDQLRRRFGDVFSLQLAWTPVVVL 81 M ++ A+YP L LP +G+L + + F +L++++G ++S+++ V++ Sbjct: 1 MAKKT--GAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIV 58 Query: 82 NGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRN 141 +E L+ G+D + RP + I +G+ A G W+ RR +++T Sbjct: 59 GHHQLAKEVLIKKGKDFSGRPQMATLDIAS--NNRKGIAFADSGAHWQLHRRLAMATFAL 116 Query: 142 LGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPR 201 G + LE+ + +E + LC A H+G+ + + AV+NVI+ + ++ DP Sbjct: 117 FKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPE 176 Query: 202 FLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMT 261 L ++ EG+ + +++ VP L P + L+ L + E+ Sbjct: 177 -LNVIQNYNEGIIDNLS-KDSLVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKE 234 Query: 262 WDPAQPPRDLTEAFL-AEMEKAKGNPESS-----FNDENLRIVVADLFSAGMVTTSTTLA 315 + ++ + + A+M GN +D ++ + D+F AG+ TT++ + Sbjct: 235 KFRSDSITNMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVK 294 Query: 316 WGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVT 375 W L ++ +P V++++ +EID +G R P + D+ + A I EV R + P+ + Sbjct: 295 WTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIP 354 Query: 376 HMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGH--FVKPEAF 433 H + D + F + KGT +I NL ++ +E W +P +F PE FL+ G ++ Sbjct: 355 HKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSY 414 Query: 434 LPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELC 493 LPF AG R+C+GE LAR ELFL LLQ F VP PS G+ + +++ Sbjct: 415 LPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGIPKVVFLIDSFKVK 474 Query: 494 AVPR 497 R Sbjct: 475 IKVR 478 >4R1Z-A nrPDB Length = 439 Score = 416 bits (1068), Expect = e-116, Method: Composition-based stats. Identities = 125/431 (29%), Positives = 210/431 (48%), Gaps = 10/431 (2%) Query: 73 LAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQR 132 + ++++N +E L+ G+ A RP T +L + + A Y W+ R Sbjct: 1 MGSHKLLIVNNHHHAKEILIKKGKIFAGRPRTVTTDLLTRD--GKDIAFADYSSTWKFHR 58 Query: 133 RFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCG 192 + L G G S+E+ + EA+ +C L +AV+NV+ +L Sbjct: 59 KMVHGALCMFGEGSVSIEKIICREASSMCEVLTESQNSAVDLGPELTRAVTNVVCALCFN 118 Query: 193 RRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLD 252 ++ D F +L +Q + + +++ P L P +LR + +L Sbjct: 119 SSYKRGDAEFESMLQYSQGIVDTVA--KDSLVDIFPWLQIFPNKDLTILRQCISIRDKLL 176 Query: 253 ELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESS----FNDENLRIVVADLFSAGMV 308 + E RDL +A L ++ N S+ ++++ + V D+F AG+ Sbjct: 177 QKKYEEHKVTYSDNVQRDLLDALLRAKRSSENNNSSTRDVGLTEDHVLMTVGDIFGAGVE 236 Query: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGD 368 TT+T L W + ++ +P VQR++Q+E+D IG+ R P++ D+ ++PY A I EV R Sbjct: 237 TTTTVLKWSIAYLVHNPQVQRKIQEELDSKIGKERHPQLSDRGNLPYLEATIREVLRIRP 296 Query: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHF- 427 + PL + H+ +D V + + KGT ++ NL S+ D+ W+ P F P FL+ +G Sbjct: 297 VSPLLIPHVALQDSSVGEYTVQKGTRVVINLWSLHHDKKEWKNPELFDPGRFLNEEGDGL 356 Query: 428 -VKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVS 486 ++LPF AG R CLGE LA+MELFLF +LQ F+ +PTGQP P G F ++ Sbjct: 357 CCPSGSYLPFGAGVRVCLGEALAKMELFLFLAWILQRFTLEMPTGQPLPDLQGKFGVVLQ 416 Query: 487 PSPYELCAVPR 497 P +++ A R Sbjct: 417 PKKFKVVAKVR 427 >2HI4-A nrPDB Length = 495 Score = 404 bits (1037), Expect = e-113, Method: Composition-based stats. Identities = 144/459 (31%), Positives = 226/459 (49%), Gaps = 19/459 (4%) Query: 26 RQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLA 85 R + PP P P LG++L + +N ++ +R+GDV +++ TPV+VL+ L Sbjct: 10 RVPKGLKSPPEPWGWPLLGHVLTLG-KNPHLALSRMSQRYGDVLQIRIGSTPVLVLSRLD 68 Query: 86 AVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLG 145 +R+ALV G+D RP + + ++ G F GP W +RR + + L + Sbjct: 69 TIRQALVRQGDDFKGRPDLYTSTLITDGQ--SLTFSTDSGPVWAARRRLAQNALNTFSIA 126 Query: 146 KK-------SLEQWVTEEAACLCAAFANHSGRP--FRPNGLLDKAVSNVIASLTCGRRFE 196 LE+ V++EA L + P F P + +V+NVI ++ G+ F Sbjct: 127 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANVIGAMCFGQHFP 186 Query: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLR-FQKAFLTQLDELL 255 L L+ E ++ S L+ P+L ++P A + + F + FL L + + Sbjct: 187 ESSDEMLSLVKNTHEFVETASS--GNPLDFFPILRYLPNPALQRFKAFNQRFLWFLQKTV 244 Query: 256 TEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLA 315 EH +D RD+T A +K + E + +V D+F AG T +T ++ Sbjct: 245 QEHYQDFDK-NSVRDITGALFKHSKKGPRASGNLIPQEKIVNLVNDIFGAGFDTVTTAIS 303 Query: 316 WGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVT 375 W L+ ++ P++QR++Q+E+D VIG+ RRP + D+ +PY A I E R +P + Sbjct: 304 WSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHSSFLPFTIP 363 Query: 376 HMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVK---PEA 432 H T+RD + GF IPK + N V D +WE P F PE FL A G + E Sbjct: 364 HSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTAINKPLSEK 423 Query: 433 FLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTG 471 + F G+R C+GE LA+ E+FLF LLQ FSVP G Sbjct: 424 MMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSVPPG 462 >6IQ5-A nrPDB Length = 463 Score = 386 bits (992), Expect = e-108, Method: Composition-based stats. Identities = 149/459 (32%), Positives = 219/459 (47%), Gaps = 22/459 (4%) Query: 55 PYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGP 114 F +L RR+GDVF ++L P+VVLNG A+ +ALV G ADRP +++ G Sbjct: 4 HLSFARLARRYGDVFQIRLGSCPIVVLNGERAIHQALVQQGSAFADRPSFASFRVVSGGR 63 Query: 115 RSQGVFLARYGPAWREQRRFSVSTLRNLGL----GKKSLEQWVTEEAACLCAAFANHS-- 168 + Y W+ QRR + S +RN ++ LE V EA L A S Sbjct: 64 S---MAFGHYSEHWKVQRRAAHSMMRNFFTRQPRSRQVLEGHVLSEARELVALLVRGSAD 120 Query: 169 GRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVP 228 G P L AV+NV++++ G R+ +DDP F LL +E + +++ +P Sbjct: 121 GAFLDPRPLTVVAVANVMSAVCFGCRYSHDDPEFRELLSHNEEFGRTVGA--GSLVDVMP 178 Query: 229 VLLHIPALAGKVLR----FQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKG 284 L + P V R + F + + H + P PRD+ +AF+ EK Sbjct: 179 WLQYFPNPVRTVFREFEQLNRNFSNFILDKFLRHCESLRPGAAPRDMMDAFILSAEKKAA 238 Query: 285 NP----ESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIG 340 + + EN+ + D+F A T ST L W LLL +PDVQ RVQ E+D V+G Sbjct: 239 GDSHGGGARLDLENVPATITDIFGASQDTLSTALQWLLLLFTRYPDVQTRVQAELDQVVG 298 Query: 341 QVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLS 400 + R P MGDQ ++PY A ++E RF VP+ + H T+ + V G+ IPK T + N Sbjct: 299 RDRLPCMGDQPNLPYVLAFLYEAMRFSSFVPVTIPHATTANTSVLGYHIPKDTVVFVNQW 358 Query: 401 SVLKDEAVWEKPFRFHPEHFLDAQGHFVK--PEAFLPFSAGRRACLGEPLARMELFLFFT 458 SV D W P F P FLD G K + FS G+R C+GE L++M+LFLF + Sbjct: 359 SVNHDPVKWPNPENFDPARFLDKDGLINKDLTSRVMIFSVGKRRCIGEELSKMQLFLFIS 418 Query: 459 SLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR 497 L F +P + + + P +++ R Sbjct: 419 ILAHQCDFRANPNEPAKMNFS-YGLTIKPKSFKVNVTLR 456 >3QZ1-A nrPDB Length = 496 Score = 380 bits (975), Expect = e-106, Method: Composition-based stats. Identities = 138/479 (28%), Positives = 220/479 (45%), Gaps = 26/479 (5%) Query: 28 RWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAV 87 RW R P +PG +LL N P L ++ G V+ L+L VVVLN + Sbjct: 22 RWKLRNLHLPPLVPGFLHLLQ---PNLPIHLLSLTQKLGPVYRLRLGLQEVVVLNSKRTI 78 Query: 88 REALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKK 147 EA++ D A RP +P +++ R Q + L Y W+ ++ + S L + Sbjct: 79 EEAMIRKWVDFAGRPQIPSYKLVS--QRCQDISLGDYSLLWKAHKKLTRSALLLG--TRS 134 Query: 148 SLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLD 207 S+E WV + C +G P ++I LT G + +D D Sbjct: 135 SMEPWVDQLTQEFCERMRVQAGAPVTIQKEFSLLTCSIICYLTFGNK---EDTLVHAFHD 191 Query: 208 LAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQ---LDELLTEHRMTWDP 264 Q+ +K + ++L+ VP L P + R ++A + +++ L H+ + Sbjct: 192 CVQDLMKTWDHWSIQILDMVPFLRFFPNPG--LWRLKQAIENRDHMVEKQLRRHKESMVA 249 Query: 265 AQPPRDLTEAFLAEMEKAK-GNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMIL 323 Q RD+T+ L + + + + ++ + V DLF G TT++TL+W + ++ Sbjct: 250 GQW-RDMTDYMLQGVGRQRVEEGPGQLLEGHVHMSVVDLFIGGTETTASTLSWAVAFLLH 308 Query: 324 HPDVQRRVQQEIDDVIG---QVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSR 380 HP++QRR+Q+E+D +G R D+A +P A I EV R +VPL + H T+R Sbjct: 309 HPEIQRRLQEELDRELGPGASCSRVTYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTR 368 Query: 381 DIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGR 440 + G+ IP+G +I NL DE VWE+P F P+ FL+ + L F G Sbjct: 369 PSSIFGYDIPEGMVVIPNLQGAHLDETVWEQPHEFRPDRFLEPGANPSA----LAFGCGA 424 Query: 441 RACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSH--HGVFAFLVSPSPYELCAVPR 497 R CLGE LAR+ELF+ LLQ F+ P PS + P+++ PR Sbjct: 425 RVCLGESLARLELFVVLARLLQAFTLLPPPVGALPSLQPDPYCGVNLKVQPFQVRLQPR 483 >5VBU-A nrPDB Length = 476 Score = 377 bits (969), Expect = e-105, Method: Composition-based stats. Identities = 136/482 (28%), Positives = 219/482 (45%), Gaps = 24/482 (4%) Query: 23 MHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLN 82 M ++ + PP PG +LL D P L ++FG ++ L L VVVLN Sbjct: 1 MAKKTSSKGKLPPLA---PGFLHLLQPDL---PIYLLGLTQKFGPIYRLHLGLQDVVVLN 54 Query: 83 GLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNL 142 + EA+V D A RP +++ + L Y W+ ++ + S L Sbjct: 55 SKRTIEEAMVKKWADFAGRPEPLTYKLVSR--NYPDLSLGDYSLLWKAHKKLTRSALLLG 112 Query: 143 GLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRF 202 + S+E V + C G P ++I LT G + + DD Sbjct: 113 --IRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTCSIICYLTFGDKIK-DDNLM 169 Query: 203 LRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDEL-LTEHRMT 261 QE LK S + ++++ +P L P + L+ + E+ L +H+ + Sbjct: 170 PAYYKCIQEVLKTWSHWSIQIVDVIPFLRFFPNPGLRRLKQAIEKRDHIVEMQLRQHKES 229 Query: 262 WDPAQPPRDLTEAFLAEMEKAK-GNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLL 320 Q RD+ + L + + + ++ + DL G TT+ TL+W ++ Sbjct: 230 LVAGQW-RDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLSWAVVF 288 Query: 321 MILHPDVQRRVQQEIDDVIG---QVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHM 377 ++ HP++Q+R+Q+E+D +G R D+A +P A I EV R +VPL + H Sbjct: 289 LLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHR 348 Query: 378 TSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFS 437 T+R + G+ IP+GT +I NL DE VWE+P F P+ FL+ K L F Sbjct: 349 TTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFLEPG----KNSRALAFG 404 Query: 438 AGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGV--FAFLVSPSPYELCAV 495 G R CLGEPLAR+ELF+ T LLQ F+ +P+G PS + + ++ P+++ Sbjct: 405 CGARVCLGEPLARLELFVVLTRLLQAFTL-LPSGDALPSLQPLPHCSVILKMQPFQVRLQ 463 Query: 496 PR 497 PR Sbjct: 464 PR 465 >5YLW-A nrPDB Length = 495 Score = 358 bits (919), Expect = 3e-99, Method: Composition-based stats. Identities = 120/488 (24%), Positives = 202/488 (41%), Gaps = 24/488 (4%) Query: 9 LAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDV 68 LA + I + L RR+R PPGP P P +GN+L + N F +L +R+G + Sbjct: 7 LAALFFIAATITFLSFRRRR---NLPPGPFPYPIVGNMLQLG-ANPHQVFAKLSKRYGPL 62 Query: 69 FSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAW 128 S+ L V+++ +E L HG+ + R S G W Sbjct: 63 MSIHLGSLYTVIVSSPEMAKEILHRHGQVFSGRTIAQAVHACDHDKISMG--FLPVASEW 120 Query: 129 REQRR------FSVSTLR-NLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKA 181 R+ R+ FS ++ + GL ++ L+Q + C + SGR Sbjct: 121 RDMRKICKEQMFSNQSMEASQGLRRQKLQQLLDHVQKC------SDSGRAVDIREAAFIT 174 Query: 182 VSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHI--PALAGK 239 N++++ + D + EG+ G + + P+L + + Sbjct: 175 TLNLMSATLFSSQATEFDSKATMEFKEIIEGVATIVG-VPNFADYFPILRPFDPQGVKRR 233 Query: 240 VLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVV 299 F L +++ L E + A P + FL + E + ++ Sbjct: 234 ADVFFGKLLAKIEGYLNERLES-KRANPNAPKKDDFLEIVVDIIQANEFKLKTHHFTHLM 292 Query: 300 ADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAV 359 DLF G T +T++ W + ++++PD R++ E+ V G + + +PY AV Sbjct: 293 LDLFVGGSDTNTTSIEWAMSELVMNPDKMARLKAELKSVAGDEKIVDESAMPKLPYLQAV 352 Query: 360 IHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEH 419 I EV R PL + D EV G+ IPKGT ++ N ++ +D ++W P F PE Sbjct: 353 IKEVMRIHPPGPLLLPRKAESDQEVNGYLIPKGTQILINAYAIGRDPSIWTDPETFDPER 412 Query: 420 FLDAQGHFVKPEA-FLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHH 478 FLD + F + LPF +GRR C G PLA L + +L+ +F + + + H Sbjct: 413 FLDNKIDFKGQDYELLPFGSGRRVCPGMPLATRILHMATATLVHNFDWKLEDDSTAAADH 472 Query: 479 GVFAFLVS 486 F V+ Sbjct: 473 AGELFGVA 480 >6DA2-A nrPDB Length = 487 Score = 335 bits (860), Expect = 2e-92, Method: Composition-based stats. Identities = 108/479 (22%), Positives = 184/479 (38%), Gaps = 54/479 (11%) Query: 35 PGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTH 94 PGP PLP LGN+L + + +++G V+ PV+ + ++ LV Sbjct: 19 PGPTPLPFLGNILSYH-KGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKE 77 Query: 95 GED--TADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQW 152 T RP P+ G + +A W+ R T + L K + Sbjct: 78 CYSVFTNRRPFGPV------GFMKSAISIAE-DEEWKRLRSLLSPTFTSGKL--KEMVPI 128 Query: 153 VTEEAACLCAAFANHS--GRPFRPNGLLDKAVSNVIASLTCG------------------ 192 + + L + G+P + +VI S + G Sbjct: 129 IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTK 188 Query: 193 --RRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQ 250 RF++ DP FL + FL +L +L+I +V F + + + Sbjct: 189 KLLRFDFLDPFFLSITVFP---------FLIPILE----VLNICVFPREVTNFLRKSVKR 235 Query: 251 LDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTT 310 + E E D + D + + + + +D L AG TT Sbjct: 236 MKESRLE-----DTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETT 290 Query: 311 STTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIV 370 S+ L++ + + HPDVQ+++Q+EID V+ P M Y V++E R I Sbjct: 291 SSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIA 350 Query: 371 PLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKP 430 + + + +D+E+ G IPKG ++ ++ +D W +P +F PE F + P Sbjct: 351 -MRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDP 409 Query: 431 EAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSP 489 + PF +G R C+G A M + L +LQ+FSF P + + L+ P Sbjct: 410 YIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFK-PCKETQIPLKLSLGGLLQPEK 467 >5FSA-A nrPDB Length = 490 Score = 331 bits (849), Expect = 4e-91, Method: Composition-based stats. Identities = 94/500 (18%), Positives = 169/500 (33%), Gaps = 60/500 (12%) Query: 23 MHRRQRWAARYPPGPLPL-PGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVL 81 M ++ PP P G+ Q F+ R+++GDVFS L + V Sbjct: 1 MAKKT------PPLVFYWIPWFGSAASYG-QQPYEFFESCRQKYGDVFSFMLLGKIMTVY 53 Query: 82 NGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRN 141 G D + FG GV EQ++F+ Sbjct: 54 LGPKGHEFVFNAKLSDVSAEEAYKHLTTPVFG---TGVIYDCPNSRLMEQKKFA-----K 105 Query: 142 LGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNV------IASLTCGRRF 195 L S +++V + + F + V+NV I T R Sbjct: 106 FALTTDSFKRYVPKIREEILNYFVTDESFKLKEK---THGVANVMKTQPEITIFTASRSL 162 Query: 196 EYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELL 255 D+ R + AQ + GF +N V L +P + +K T + E+ Sbjct: 163 FGDEMRRIFDRSFAQLYSDLDKGFTP--INFVFPNLPLPHYWRRDAAQKKISATYMKEI- 219 Query: 256 TEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLA 315 + R P RDL ++ L G D+ + ++ + G T+++T A Sbjct: 220 -KLRRERGDIDPNRDLIDSLLIHSTYKDG---VKMTDQEIANLLIGILMGGQHTSASTSA 275 Query: 316 WGLLLMILHPDVQRRVQQEIDDVI----GQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVP 371 W LL + P +Q + QE+ +++ G + D +P I E R + Sbjct: 276 WFLLHLGEKPHLQDVIYQEVVELLKEKGGDLNDLTYEDLQKLPSVNNTIKETLRMHMPLH 335 Query: 372 LGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVK 429 + + + + + +PKG ++ + E ++ P F P + A Sbjct: 336 -SIFRKVTNPLRIPETNYIVPKGHYVLVSPGYAHTSERYFDNPEDFDPTRWDTAAAKANS 394 Query: 430 --------------------PEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVP 469 +LPF GR C+GE A ++L T+ + + +++ Sbjct: 395 VSFNSSDEVDYGFGKVSKGVSSPYLPFGGGRHRCIGEQFAYVQLGTILTTFVYNLRWTID 454 Query: 470 TGQ-PRPSHHGVFAFLVSPS 488 + P P + + P+ Sbjct: 455 GYKVPDPDYSSMVVLPTEPA 474 >5JLC-A nrPDB Length = 515 Score = 327 bits (839), Expect = 6e-90, Method: Composition-based stats. Identities = 105/524 (20%), Positives = 180/524 (34%), Gaps = 69/524 (13%) Query: 7 VPLAVIVAIFLLLVDL---------MHRRQRWAARYPPGPLPL-PGLGNLLHVDFQNTPY 56 +PLA V+I + L + R+ R PP P +G+ + + PY Sbjct: 7 LPLAQRVSIMVALPFVYTITWQLLYSLRKDR-----PPLVFYWIPWVGS--AIPYGTKPY 59 Query: 57 -CFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115 F+ ++++GD+FS L + V G D + FG Sbjct: 60 EFFEDCQKKYGDIFSFMLLGRIMTVYLGPKGHEFIFNAKLADVSAEAAYSHLTTPVFG-- 117 Query: 116 SQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPN 175 +GV EQ++F L K++ ++V A + F N N Sbjct: 118 -KGVIYDCPNHRLMEQKKFVKGAL-----TKEAFVRYVPLIAEEIYKYFRNSKNFKINEN 171 Query: 176 --GLLDKAVSN-VIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH 232 G++D VS + T R + R D A + GF P+ Sbjct: 172 NSGIVDVMVSQPEMTIFTASRSLLGKEMRDKLDTDFAYLYSDLDKGFT-------PINFV 224 Query: 233 IPALAGKVLR----FQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPES 288 P L + R Q+A L+ E R D RDL + + G + Sbjct: 225 FPNLPLEHYRKRDHAQQAISGTYMSLIKERREKNDIQN--RDLIDELMKNSTYKDG---T 279 Query: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVI-GQVRRPEM 347 D+ + ++ + G T++ T AW LL + PDVQ + QE V+ + Sbjct: 280 KMTDQEIANLLIGVLMGGQHTSAATSAWCLLHLAERPDVQEELYQEQMRVLNNDTKELTY 339 Query: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV--QGFRIPKGTTLITNLSSVLKD 405 D +MP +I E R + + RD+ + + +P+ ++ + Sbjct: 340 DDLQNMPLLNQMIKETLRLHHPLH-SLFRKVMRDVAIPNTSYVVPRDYHVLVSPGYTHLQ 398 Query: 406 EAVWEKPFRFHPEHFLDAQGHFVK-----------------PEAFLPFSAGRRACLGEPL 448 E + KP F+ + +LPF GR C+GE Sbjct: 399 EEFFPKPNEFNIHRWDGDAASSSAAGGDEVDYGFGAISKGVSSPYLPFGGGRHRCIGELF 458 Query: 449 ARMELFLFFTSLLQHFSFSVPT-GQPRPSHH--GVFAFLVSPSP 489 A +L + + ++ + PT G+ P + +P+ Sbjct: 459 AYCQLGVLMSIFIRTMKWRYPTEGETVPPSDFTSMVTLPTAPAK 502 >4WMZ-A nrPDB Length = 539 Score = 327 bits (838), Expect = 8e-90, Method: Composition-based stats. Identities = 91/485 (18%), Positives = 163/485 (33%), Gaps = 51/485 (10%) Query: 34 PPGPLPL-PGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALV 92 PP P +G+ + + F++ ++++GD+FS L + V G Sbjct: 56 PPLVFYWIPWVGSAVVYGMK-PYEFFEECQKKYGDIFSFVLLGRVMTVYLGPKGHEFVFN 114 Query: 93 THGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQW 152 D + FG +GV EQ++F L K++ + + Sbjct: 115 AKLADVSAEAAYAHLTTPVFG---KGVIYDCPNSRLMEQKKFVKGAL-----TKEAFKSY 166 Query: 153 VTEEAACLCAAFANHSGRPFRP--NGLLDKAVSN-VIASLTCGRRFEYDDPRFLRLLDLA 209 V A + F + G +D V+ + T R + R D A Sbjct: 167 VPLIAEEVYKYFRDSKNFRLNERTTGTIDVMVTQPEMTIFTASRSLLGKEMRAKLDTDFA 226 Query: 210 QEGLKEESGFLREVLNAVPVLLHIPALAGKVLR----FQKAFLTQLDELLTEHRMTWDPA 265 + GF P+ P L + R QKA L+ E R D Sbjct: 227 YLYSDLDKGFT-------PINFVFPNLPLEHYRKRDHAQKAISGTYMSLIKERRKNNDIQ 279 Query: 266 QPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHP 325 RDL ++ + G D+ + ++ + G T++ T AW LL + P Sbjct: 280 D--RDLIDSLMKNSTYKDG---VKMTDQEIANLLIGVLMGGQHTSAATSAWILLHLAERP 334 Query: 326 DVQRRVQQEIDDVIGQVRRPEMGDQ-AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV 384 DVQ+ + +E V+ ++ D MP I E R + + +D+ V Sbjct: 335 DVQQELYEEQMRVLDGGKKELTYDLLQEMPLLNQTIKETLRMHHPLH-SLFRKVMKDMHV 393 Query: 385 --QGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVK------------- 429 + IP G ++ + + + +F+ + + Sbjct: 394 PNTSYVIPAGYHVLVSPGYTHLRDEYFPNAHQFNIHRWNNDSASSYSVGEEVDYGFGAIS 453 Query: 430 ---PEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQ--PRPSHHGVFAFL 484 +LPF GR C+GE A +L + + ++ + P G+ P P + Sbjct: 454 KGVSSPYLPFGGGRHRCIGEHFAYCQLGVLMSIFIRTLKWHYPEGKTVPPPDFTSMVTLP 513 Query: 485 VSPSP 489 P+ Sbjct: 514 TGPAK 518 >5VEU-A nrPDB Length = 480 Score = 322 bits (826), Expect = 2e-88, Method: Composition-based stats. Identities = 104/464 (22%), Positives = 183/464 (39%), Gaps = 25/464 (5%) Query: 35 PGPLPLPGLGNLLHVDFQNTPYCF-DQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93 PGP PLP LGN+L ++ + F + +++G ++ PV+ + +R LV Sbjct: 18 PGPTPLPLLGNVLS--YRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVK 75 Query: 94 HGED--TADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151 T R P+ G + LA W+ R T + L K + Sbjct: 76 ECYSVFTNRRSLGPV------GFMKSAISLAE-DEEWKRIRSLLSPTFTSGKL--KEMFP 126 Query: 152 WVTEEAACLCAAFANH--SGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLA 209 + + L G+P + +VI + G + + ++ Sbjct: 127 IIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQDPFVEST 186 Query: 210 QEGLKEESGFLREVLNAVPVLLHI-PAL-AGKVLRFQKAFLTQLDELLTEHRMT--WDPA 265 ++ LK GFL + ++ + + P A V F K + L + + + + D Sbjct: 187 KKFLKF--GFLDPLFLSIILFPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSRLNDKQ 244 Query: 266 QPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHP 325 + D + + + + +D L AG TTS+ L++ L + HP Sbjct: 245 KHRLDFLQLMIDSQNSKETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHP 304 Query: 326 DVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQ 385 DVQ+++Q+EID V+ P M Y V++E R + + + +D+E+ Sbjct: 305 DVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVA-IRLERTCKKDVEIN 363 Query: 386 GFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLG 445 G IPKG+ ++ ++ D W +P F PE F + + P + PF G R C+G Sbjct: 364 GVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERF-SKKKDSIDPYIYTPFGTGPRNCIG 422 Query: 446 EPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSP 489 A M + L +LQ+FSF P + + L+ P Sbjct: 423 MRFALMNMKLALIRVLQNFSFK-PCKETQIPLKLDTQGLLQPEK 465 >3L4D-A nrPDB Length = 453 Score = 298 bits (762), Expect = 4e-81, Method: Composition-based stats. Identities = 93/467 (19%), Positives = 187/467 (40%), Gaps = 39/467 (8%) Query: 30 AARYPPGPLPL-PGLGNLLHVDFQNTPYCFD-QLRRRFGDVFSLQLAWTPVVVLNGLAAV 87 + PP P +G+++ F P F + ++++G +F++ + + V+ + Sbjct: 1 KGKLPPVVHGTTPFVGHIIQ--FGKDPLGFMLKAKKKYGGIFTMNICGNRITVVGDVHQH 58 Query: 88 REALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRF-----SVSTLRNL 142 + E + R V + FG +GV A P REQ F +V+ +N Sbjct: 59 SKFFTPRNEILSPRE-VYSFMVPVFG---EGVAYAAPYPRMREQLNFLAEELTVAKFQNF 114 Query: 143 GLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRF 202 S++ V + AN + N L D S +I + C F D + Sbjct: 115 A---PSIQHEVRKFMK------ANWNKDEGEINILDDC--SAMIINTACQCLFGEDLRKR 163 Query: 203 LRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTW 262 L AQ K ES + + +P +L +P R +A +L ++L+E + Sbjct: 164 LDARQFAQLLAKMESCLIPAAV-FLPWILKLPLPQSYRCRDARA---ELQDILSEIIIAR 219 Query: 263 DPAQPPRDL-TEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLM 321 + + +D T LA + A + + + ++ AG T++ T W LL + Sbjct: 220 EKEEAQKDTNTSDLLAGLLGAVYRDGTRMSQHEVCGMIVAAMFAGQHTSTITTTWSLLHL 279 Query: 322 I--LHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTS 379 + + ++ QEID+ Q+ + ++ MP+ E R + + + Sbjct: 280 MDPRNKRHLAKLHQEIDEFPAQLNYDNVMEE--MPFAEQCARESIRRDPPL-VMLMRKVL 336 Query: 380 RDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAG 439 + ++V + +P+G + + +DE + P ++PE + + AF F AG Sbjct: 337 KPVQVGKYVVPEGDIIACSPLLSHQDEEAFPNPREWNPERNMK-----LVDGAFCGFGAG 391 Query: 440 RRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVS 486 C+GE +++ ++L+ + F + P P++H + + Sbjct: 392 VHKCIGEKFGLLQVKTVLATVLRDYDFELLGPLPEPNYHTMVVGPTA 438 >2VE3-A nrPDB Length = 444 Score = 280 bits (716), Expect = 1e-75, Method: Composition-based stats. Identities = 116/467 (24%), Positives = 190/467 (40%), Gaps = 61/467 (13%) Query: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93 PPG LP LG L +F N + +++FG +F +L V+ ++G A R Sbjct: 14 PPGDFGLPWLGETL--NFLNDGDFGKKRQQQFGPIFKTRLFGKNVIFISGALANRFLFTK 71 Query: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRR-----FSVSTLRNL-----G 143 E + P++ + GP + + G R +R+ F TL + G Sbjct: 72 EQETF--QATWPLSTRILLGPNA---LATQMGEIHRSRRKILYQAFLPRTLDSYLPKMDG 126 Query: 144 LGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFL 203 + + LEQW + +V A+L G + +P+ Sbjct: 127 IVQGYLEQWGKANEVIWYPQLR--------------RMTFDVAATLFMGEKVS-QNPQLF 171 Query: 204 RLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWD 263 + +G L ++P+ L L GK R + L +L++++ + Sbjct: 172 PWFETYIQG-----------LFSLPIPLP-NTLFGKSQRARALLLAELEKIIKARQQ--- 216 Query: 264 PAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMIL 323 QPP + E L + A+ + + L+ + L AG T ++ L+ LL+ Sbjct: 217 --QPPSE--EDALGILLAARDDNNQPLSLPELKDQILLLLFAGHETLTSALSSFCLLLGQ 272 Query: 324 HPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIE 383 H D++ RV+QE + + + MPY V+ EV R V G +D + Sbjct: 273 HSDIRERVRQEQNK-LQLSQELTAETLKKMPYLDQVLQEVLRLIPPVGGG-FRELIQDCQ 330 Query: 384 VQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHF-LDAQGHFVKPEAFLPFSAGRRA 442 QGF PKG + +S D ++ P +F PE F D P A +PF G R Sbjct: 331 FQGFHFPKGWLVSYQISQTHADPDLYPDPEKFDPERFTPDGSATHNPPFAHVPFGGGLRE 390 Query: 443 CLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSP 489 CLG+ AR+E+ LF T L+Q F +++ GQ +V+PSP Sbjct: 391 CLGKEFARLEMKLFATRLIQQFDWTLLPGQ-------NLELVVTPSP 430 >2WX2-A nrPDB Length = 473 Score = 274 bits (700), Expect = 7e-74, Method: Composition-based stats. Identities = 97/458 (21%), Positives = 173/458 (37%), Gaps = 31/458 (6%) Query: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRR--FGDVFSLQLAWTPVVVLNGLAAVREAL 91 P P+ +P LG+++ F P F Q +R VF++ + V ++ Sbjct: 19 PVYPVTVPFLGHIVQ--FGKNPLEFMQRCKRDLKSGVFTISIGGQRVTIVGDPHEHSRFF 76 Query: 92 VTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151 E + R V FG +GV A P REQ F L ++ Sbjct: 77 SPRNEILSPRE-VYTIMTPVFG---EGVAYAAPYPRMREQLNFLAEELTIAKF--QNFVP 130 Query: 152 WVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQE 211 + E A N N L D +I + C F D + L AQ Sbjct: 131 AIQHEVRKFMAE--NWKEDEGVINLLEDCG--AMIINTACQCLFGEDLRKRLNARHFAQL 186 Query: 212 GLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDL 271 K ES + + +P LL +P R +A +L ++L E + + + +D Sbjct: 187 LSKMESSLIPAAV-FMPWLLRLPLPQSARCREARA---ELQKILGEIIVAREKEEASKDN 242 Query: 272 -TEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMIL--HPDVQ 328 T L + KA + + + ++ AG T++ T +W +L ++ + Sbjct: 243 NTSDLLGGLLKAVYRDGTRMSLHEVCGMIVAAMFAGQHTSTITTSWSMLHLMHPKNKKWL 302 Query: 329 RRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFR 388 ++ +EID+ Q+ + D+ MP+ + E R + L V M +++V + Sbjct: 303 DKLHKEIDEFPAQLNYDNVMDE--MPFAERCVRESIRRDPPL-LMVMRMVKAEVKVGSYV 359 Query: 389 IPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPL 448 +PKG + + DE + P + PE G AF+ F AG C+G+ Sbjct: 360 VPKGDIIACSPLLSHHDEEAFPNPRLWDPERDEKVDG------AFIGFGAGVHKCIGQKF 413 Query: 449 ARMELFLFFTSLLQHFSFSVPTGQ-PRPSHHGVFAFLV 485 A +++ + + + F + + P P +H + Sbjct: 414 ALLQVKTILATAFREYDFQLLRDEVPDPDYHTMVVGPT 451 >6AYB-A nrPDB Length = 466 Score = 268 bits (685), Expect = 4e-72, Method: Composition-based stats. Identities = 89/474 (18%), Positives = 171/474 (36%), Gaps = 30/474 (6%) Query: 23 MHRRQRWAARYPPG-PLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVL 81 M ++ + PP P +P +G+ + +N +++GDVF+ + + L Sbjct: 1 MAKKTSSKGKLPPRVPNLIPYVGSFVSF-AKNPVQFIIDNSKKYGDVFTATILGKEMTFL 59 Query: 82 NGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFL-ARYGPAWREQRRFSVSTLR 140 N + + + R V FG GV A EQ +F S L Sbjct: 60 NHPKILDTFFKATDNELSLR-DVYRFMRPVFG---TGVVYDADSTERMMEQVKFVSSGLT 115 Query: 141 N--LGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYD 198 + E + + L L+ +++I + Sbjct: 116 TARFRVFVDIFEDEIAHKVKELGPE------GTVDVAELM----ADLIIFTASRCLLGDE 165 Query: 199 DPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEH 258 ++L +L + + G P+ P+L + + ++ + L + Sbjct: 166 VRQYLSEKNLGKLYHDIDDGIS-------PLSFFYPSLPAPKRDKARKAVGEIFQELLDK 218 Query: 259 RMTWDPAQPPRDLTE---AFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLA 315 R P R L E + + K D + ++ AG T+S T + Sbjct: 219 RREEHKKHPERLLDESKMDVVDHLLTQKYKDGQELTDVHRIGILIAGLFAGQHTSSITSS 278 Query: 316 WGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVT 375 W L+ +I + V +V++E ++++G + + M Y A + E R + + + Sbjct: 279 WTLMNVISNKKVLEKVRKEQEEIMGSDKVLDYDKVMKMDYLEACMKEALRMYPPL-IMIM 337 Query: 376 HMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLP 435 M + E + + IPKG L+ + S + + P F PE + + H +P Sbjct: 338 RMARKPRECEQYIIPKGNILVVSPSVAGRCTDTYTNPDVFDPERLTERKEHEKFKYGAVP 397 Query: 436 FSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSP 489 F AGR C+GE A +++ + LL++F P PS+ + P+ Sbjct: 398 FGAGRHKCIGENFALLQVKSIISILLRYFDMEYIGKIPDPSYTSLVVGPSPPTR 451 >6CR2-A nrPDB Length = 477 Score = 267 bits (683), Expect = 7e-72, Method: Composition-based stats. Identities = 90/492 (18%), Positives = 156/492 (31%), Gaps = 47/492 (9%) Query: 23 MHRRQRWAARYPPGPLPL-PGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVL 81 M ++ PP P +G+ + + F R ++GD+F+ L V Sbjct: 1 MAKKT------PPVVFHWFPFIGSTISYGI-DPYKFFFDCRAKYGDIFTFILLGKKTTVY 53 Query: 82 NGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRN 141 G L D FG V EQ++F Sbjct: 54 LGTKGNDFILNGKLRDVCAEEVYSPLTTPVFGRH---VVYDCPNAKLMEQKKFV-----K 105 Query: 142 LGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPR 201 GL +L +V + + N I T R + + R Sbjct: 106 YGLTSDALRSYVPLITDEVESFVKNSPAFQGHKGVFDVCKTIAEITIYTASRSLQGKEVR 165 Query: 202 FLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMT 261 A+ + GF P+ +P R + A +L E E Sbjct: 166 SKFDSTFAELYHNLDMGFA-------PINFMLPWAPLPHNRKRDAAQRKLTETYMEIIKA 218 Query: 262 WDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLM 321 A +D +E + + + DE + ++ L AG ++S+T +W +L + Sbjct: 219 RRQAGSKKD-SEDMVWNLMSCVYKNGTPVPDEEIAHMMIALLMAGQHSSSSTASWIVLRL 277 Query: 322 ILHPDVQRRVQQEIDDVIGQVRRPEMGD-QAHMPYTTAVIHEVQRFGDIVPLGVTHMTSR 380 PD+ + QE V+G P D + VI E R + + Sbjct: 278 ATRPDIMEELYQEQIRVLGSDLPPLTYDNLQKLDLHAKVIKETLRLHAPIH-SIIRAVKN 336 Query: 381 DIEVQG--FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV---------- 428 + V G + IP ++++ + E + P ++P + + Sbjct: 337 PMAVDGTSYVIPTSHNVLSSPGVTARSEEHFPNPLEWNPHRWDENIAASAEDDEKVDYGY 396 Query: 429 ------KPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPT---GQPRPSHHG 479 +LPF AGR C+GE A ++L L++ F F G P + Sbjct: 397 GLVSKGTNSPYLPFGAGRHRCIGEQFAYLQLGTITAVLVRLFRFRNLPGVDGIPDTDYSS 456 Query: 480 VFAFLVSPSPYE 491 +F+ + S E Sbjct: 457 LFSKPLGRSFVE 468 >3JUS-A nrPDB Length = 461 Score = 256 bits (655), Expect = 1e-68, Method: Composition-based stats. Identities = 90/452 (19%), Positives = 167/452 (36%), Gaps = 26/452 (5%) Query: 23 MHRRQRWAA-RYPPGPL-PLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVV 80 M ++ A + PP P+P LG+ + ++ + ++G VFS + Sbjct: 1 MAKKTLPAGVKSPPYIFSPIPFLGHAIAFG-KSPIEFLENAYEKYGPVFSFTMVGKTFTY 59 Query: 81 LNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLR 140 L G A + ED FG +GV P + EQ++ S Sbjct: 60 LLGSDAAALLFNSKNEDLNAEDVYSRLTTPVFG---KGVAYDVPNPVFLEQKKMLKS--- 113 Query: 141 NLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDP 200 GL +Q V+ F + G N + +A+S +I + Sbjct: 114 --GLNIAHFKQHVSIIEKETKEYFESW-GESGEKN--VFEALSELIILTASHC-LHGKEI 167 Query: 201 RFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRM 260 R +AQ + GF +P L +P+ + R + + + + R Sbjct: 168 RSQLNEKVAQLYADLDGGFSHAAW-LLPGWLPLPSFRRRD-RAHREIKDIFYKAIQKRRQ 225 Query: 261 TWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLL 320 + + + L + A D+ + ++ L AG T+STT AW Sbjct: 226 SQEK-------IDDILQTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFF 278 Query: 321 MILHPDVQRRVQQEIDDVIGQVRRPEMGDQ-AHMPYTTAVIHEVQRFGDIVPLGVTHMTS 379 + +Q++ E V G+ P DQ + I E R + + + M Sbjct: 279 LARDKTLQKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMI-MMRMAR 337 Query: 380 RDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAG 439 V G+ IP G + + + + + W + F+P+ +L + A++PF AG Sbjct: 338 TPQTVAGYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAG 397 Query: 440 RRACLGEPLARMELFLFFTSLLQHFSFSVPTG 471 R C+GE A +++ ++++L+ + F + G Sbjct: 398 RHRCIGENFAYVQIKTIWSTMLRLYEFDLIDG 429 >2X2N-A nrPDB Length = 475 Score = 254 bits (648), Expect = 8e-68, Method: Composition-based stats. Identities = 97/460 (21%), Positives = 180/460 (39%), Gaps = 33/460 (7%) Query: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQ-LRRRF-GDVFSLQLAWTPVVVLNGLAAVREAL 91 P P+ +P LG+++ F +P F Q +R+ +F++ + V ++ Sbjct: 19 PVYPVTVPILGHIIQ--FGKSPLGFMQECKRQLKSGIFTINIVGKRVTIVGDPHEHSRFF 76 Query: 92 VTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151 + E + R V + FG +GV A P REQ F L ++ Sbjct: 77 LPRNEVLSPRE-VYSFMVPVFG---EGVAYAAPYPRMREQLNFLAEELTIAKF--QNFVP 130 Query: 152 WVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQE 211 + E A AN N L D + +I + C F D + L AQ Sbjct: 131 AIQHEVRKFMA--ANWDKDEGEINLLEDCST--MIINTACQCLFGEDLRKRLDARRFAQL 186 Query: 212 GLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDL 271 K ES + AV + + + + R +A T+L ++L+E + A +D Sbjct: 187 LAKMESSLIPA---AVFLPILLKLPLPQSARCHEA-RTELQKILSEIIIARKAAAVNKDS 242 Query: 272 -TEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHP---DV 327 T L+ + A + + + ++ AG T+S T W +L ++ HP Sbjct: 243 STSDLLSGLLSAVYRDGTPMSLHEVCGMIVAAMFAGQHTSSITTTWSMLHLM-HPANVKH 301 Query: 328 QRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGF 387 +++EI++ Q+ + D+ MP+ E R + L + D++V + Sbjct: 302 LEALRKEIEEFPAQLNYNNVMDE--MPFAERCARESIRRDPPL-LMLMRKVMADVKVGSY 358 Query: 388 RIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEP 447 +PKG + + DE + +P R+ PE +G AF+ F AG C+G+ Sbjct: 359 VVPKGDIIACSPLLSHHDEEAFPEPRRWDPERDEKVEG------AFIGFGAGVHKCIGQK 412 Query: 448 LARMELFLFFTSLLQHFSFSVPTGQ-PRPSHHGVFAFLVS 486 +++ + + + F + + P P +H + + Sbjct: 413 FGLLQVKTILATAFRSYDFQLLRDEVPDPDYHTMVVGPTA 452 >3K9V-A nrPDB Length = 482 Score = 239 bits (610), Expect = 2e-63, Method: Composition-based stats. Identities = 98/470 (20%), Positives = 167/470 (35%), Gaps = 21/470 (4%) Query: 35 PGPLPLPGLGNLLHV----DFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREA 90 PGP P LG+LL + + + +++G +F ++L V L + + EA Sbjct: 27 PGPTNWPLLGSLLEIFWKGGLKKQHDTLAEYHKKYGQIFRMKLGSFDSVHLGSPSLL-EA 85 Query: 91 LVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLE 150 L R + + + G W+ R L K + Sbjct: 86 LYRTESAHPQRLEIKPWKAYRDHRNEAYGLMILEGQEWQRVRSAFQKKLMKPVEIMKLDK 145 Query: 151 QWVTEEAACL--CAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208 + A L + GR L+K I + +RF Sbjct: 146 KINEVLADFLERMDELCDERGRIPDLYSELNKWSFESICLVLYEKRFGLLQKETEEEALT 205 Query: 209 AQEGLK-EESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQP 267 +K S F + ++ V + + + + + + ++R+ QP Sbjct: 206 FITAIKTMMSTFGKMMVTPVELHKRLNTKVWQAHTLAWDTIFKSVKPCIDNRLQRYSQQP 265 Query: 268 PRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDV 327 D + + + L V +L A + TT+ +L W L + +P Sbjct: 266 GADFLCDIY---------QQDHLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQA 316 Query: 328 QRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGF 387 QRR+ QE+ V+ + P D +MPY A + E R VP T + + + Sbjct: 317 QRRLLQEVQSVLPDNQTPRAEDLRNMPYLKACLKESMRLTPSVPF-TTRTLDKPTVLGEY 375 Query: 388 RIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEP 447 +PKGT L N + E +E +F PE +L + + P A LPF G+R C+G Sbjct: 376 ALPKGTVLTLNTQVLGSSEDNFEDSHKFRPERWLQKEKK-INPFAHLPFGIGKRMCIGRR 434 Query: 448 LARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR 497 LA ++L L ++Q + +P H LV + PR Sbjct: 435 LAELQLHLALCWIIQKYDIVATDNEPVEMLH--LGILVPSRELPIAFRPR 482 >3MDV-A nrPDB Length = 456 Score = 231 bits (588), Expect = 6e-61, Method: Composition-based stats. Identities = 85/420 (20%), Positives = 158/420 (37%), Gaps = 18/420 (4%) Query: 56 YCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115 F +++G V + + V++ +V++ L++ + + + + G Sbjct: 14 DVFLDWAKKYGPVVRVNVFHKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLF 73 Query: 116 SQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAF--ANHSGRPFR 173 QG+ W +QRR L SL + E+A L P Sbjct: 74 GQGLVSECNYERWHKQRRVIDLAFSRSSLV--SLMETFNEKAEQLVEILEAKADGQTPVS 131 Query: 174 PNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHI 233 +L +++A G L + L+ + + +P Sbjct: 132 MQDMLTYTAMDILAKAAFGMETSMLLGAQKPLSQAVKLMLEGITASRNTLAKFLPGKRKQ 191 Query: 234 PALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQP-PRDLTEAFLAEMEKAKGNPESSFND 292 + +RF + + + R + P D+ L E A+ +D Sbjct: 192 LREVRESIRFLRQVG---RDWVQRRREALKRGEEVPADILTQILKAEEGAQ-------DD 241 Query: 293 ENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAH 352 E L F AG T++ LA+ ++ + P++ R+Q E+D+VIG R + D Sbjct: 242 EGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDLGR 301 Query: 353 MPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKP 412 + Y + V+ E R G + + + G R+P T L+ + + + + +E P Sbjct: 302 LQYLSQVLKESLRLYPPA-WGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDP 360 Query: 413 FRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQ 472 F+P+ F G + PFS G R+C+G+ A+ME+ + LLQ F + GQ Sbjct: 361 LTFNPDRFGP--GAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRLVPGQ 418 >3EL3-A nrPDB Length = 467 Score = 231 bits (588), Expect = 8e-61, Method: Composition-based stats. Identities = 104/439 (23%), Positives = 169/439 (38%), Gaps = 30/439 (6%) Query: 39 PLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDT 98 +P LG+ + P F R GDV ++L V + + Sbjct: 30 GVPLLGHGWRLAR--DPLAFMSQLRDHGDVVRIKLGPKTVYAVTNPELTGALALNPDYHI 87 Query: 99 ADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAA 158 A P+ + L +GV A GP R QRR R + + + EEA Sbjct: 88 AG----PLWESLEGLLGKEGVATAN-GPLHRRQRRTIQPAFRLDAI--PAYGPIMEEEAH 140 Query: 159 CLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESG 218 L G+ + V A C R +Y D R RL + G Sbjct: 141 ALTE--RWQPGKTVDATSESFRVAVRVAAR--CLLRGQYMDERAERLCVALATVFR---G 193 Query: 219 FLREVLNAVPVLLHIPALAGKVLRFQKAFLTQ---LDELLTEHRMTWDPAQPPRDLTEAF 275 R ++ + L +P A + RF A +DE++ E R + Q P DL A Sbjct: 194 MYRRMVVPLGPLYRLPLPANR--RFNDALADLHLLVDEIIAERRAS---GQKPDDLLTAL 248 Query: 276 LAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEI 335 L +AK + ++ + V + + G T ++T+ W L + HP+ R++ E+ Sbjct: 249 L----EAKDDNGDPIGEQEIHDQVVAILTPGSETIASTIMWLLQALADHPEHADRIRDEV 304 Query: 336 DDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTL 395 + V G R D + +T VI E R V + +T + E+ G+RIP G + Sbjct: 305 EAVTGG-RPVAFEDVRKLRHTGNVIVEAMRLRPAVWV-LTRRAVAESELGGYRIPAGADI 362 Query: 396 ITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFL 455 I + ++ +D ++ F P+ +L + V A PFSAG+R C + + +L L Sbjct: 363 IYSPYAIQRDPKSYDDNLEFDPDRWLPERAANVPKYAMKPFSAGKRKCPSDHFSMAQLTL 422 Query: 456 FFTSLLQHFSFSVPTGQPR 474 +L + F G Sbjct: 423 ITAALATKYRFEQVAGSND 441 >3S79-A nrPDB Length = 503 Score = 229 bits (583), Expect = 3e-60, Method: Composition-based stats. Identities = 99/482 (20%), Positives = 179/482 (37%), Gaps = 53/482 (10%) Query: 35 PGPL------PLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVR 88 PGP PL G L + + ++++ +G+ + ++ ++++ + Sbjct: 48 PGPGYCMGIGPLISHGRFLWMGIGSACNYYNRV---YGEFMRVWISGEETLIIS--KSSS 102 Query: 89 EALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS 148 + + R + G +G+ W+ R F + L GL + Sbjct: 103 MFHIMKHNHYSSR-FGSKLGLQCIGMHEKGIIFNNNPELWKTTRPFFMKALSGPGLVR-- 159 Query: 149 LEQWVTEEAACLC-AAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYD--DPRFLRL 205 +C + H R S + LT RR D + FLR+ Sbjct: 160 --------MVTVCAESLKTHLDRLEEVTNE-----SGYVDVLTLLRRVMLDTSNTLFLRI 206 Query: 206 -LDLAQEGLKEESGF--LREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRM-- 260 LD + +K + F + +L + I L K + K ++ L+ E R Sbjct: 207 PLDESAIVVKIQGYFDAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRI 266 Query: 261 -TWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLL 319 T + + D + ++ EN+ + ++ A T S +L + L Sbjct: 267 STEEKLEECMDFATELILAEKR------GDLTRENVNQCILEMLIAAPDTMSVSLFFMLF 320 Query: 320 LMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTS 379 L+ HP+V+ + +EI VIG+ R ++ D + I+E R+ +V L V Sbjct: 321 LIAKHPNVEEAIIKEIQTVIGE-RDIKIDDIQKLKVMENFIYESMRYQPVVDL-VMRKAL 378 Query: 380 RDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAG 439 D + G+ + KGT +I N+ + + E + KP F E+F V F PF G Sbjct: 379 EDDVIDGYPVKKGTNIILNIGRMHRLE-FFPKPNEFTLENF----AKNVPYRYFQPFGFG 433 Query: 440 RRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSP----YELCAV 495 R C G+ +A + + +LL+ F GQ S + + P E+ Sbjct: 434 PRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLHPDETKNMLEMIFT 493 Query: 496 PR 497 PR Sbjct: 494 PR 495 >6C94-A nrPDB Length = 497 Score = 228 bits (580), Expect = 6e-60, Method: Composition-based stats. Identities = 88/449 (19%), Positives = 155/449 (34%), Gaps = 28/449 (6%) Query: 35 PGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTP-VVVLNGLAAVREALVT 93 PGP G+ L + + ++F L + + + + Sbjct: 25 PGPPTHWLFGHALEIQKTGSLDKVVTWTQQFPYAHPLWVGQFIGFLNIYEPDYAKAVYSR 84 Query: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWV 153 P P +G+ + GP W + R+ L+ +V Sbjct: 85 ------GDPKAPDVYDFFLQWIGKGLLVLD-GPKWFQHRKLLTPGFHY-----DVLKPYV 132 Query: 154 TEEAACLCAAFANHS-----GRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208 A G+ F + + + T G+ + R Sbjct: 133 AIFADSTRIMLEKWEKKACEGKSFDIFSDVGHMALDTLMKCTFGKGDSGLNHRDSSYYVA 192 Query: 209 AQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTW------ 262 E + + + + LR +A D ++ + + Sbjct: 193 VSELTLLMQQRIDSFQYHNDFIYWLTPHGRRFLRACRAAHDHTDRVIRQRKAALQDEKER 252 Query: 263 DPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMI 322 + Q R L FL + +G +D +LR V G TT++ ++W L M Sbjct: 253 EKIQNRRHL--DFLDILLDVRGESGVQLSDTDLRAEVDTFMFEGHDTTTSGISWFLYCMA 310 Query: 323 LHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDI 382 L+P+ Q+R ++E+ +++G + D A M Y T + E R VP V S+ + Sbjct: 311 LYPEHQQRCREEVREILGDQDSFQWEDLAKMTYLTMCMKECFRLYPPVP-QVYRQLSKPV 369 Query: 383 E-VQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRR 441 V G +P G+ + ++ ++ ++ VW P F P F P AF+PFSAG R Sbjct: 370 SFVDGRSLPAGSLISLHIYALHRNSDVWPDPEVFDPLRFSPENSSGRHPYAFIPFSAGPR 429 Query: 442 ACLGEPLARMELFLFFTSLLQHFSFSVPT 470 C+G+ A E+ + L F FSV Sbjct: 430 NCIGQQFAMNEMKVVTALCLLRFEFSVDP 458 >2W0A-A nrPDB Length = 455 Score = 226 bits (577), Expect = 1e-59, Method: Composition-based stats. Identities = 94/449 (20%), Positives = 167/449 (37%), Gaps = 38/449 (8%) Query: 50 DFQNTPYCFD-QLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQ 108 +F+ P ++R GDV + QLA VV+L+G A E G+D D+ Sbjct: 21 EFRTDPIGLMQRVRDELGDVGTFQLAGKQVVLLSGSHAN-EFFFRAGDDDLDQAKAYPFM 79 Query: 109 ILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANH- 167 FG + V +E L N L + ++ + A+ Sbjct: 80 TPIFG---EAVVFDASPERRKEM-------LHNAALRGEQMKGHAATIEDQVRRMIADWG 129 Query: 168 SGRPFRPNGLLDKAVSNVIASLTCGRRF-EYDDPRFLRLLDLAQEGLKEESGFLREVLNA 226 + ++ G++F + D RF +L + G Sbjct: 130 EAGEIDLLDFFAELTIYTSSACLIGKKFRDQLDGRFAKLYHELERGTD------------ 177 Query: 227 VPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTE----AFLAEMEKA 282 P+ P L + R + L L+ + M A PP D ++ L ++ Sbjct: 178 -PLAYVDPYLPIESFRRRDEARNGLVALVADI-MNGRIANPPTDKSDRDMLDVLIAVKAE 235 Query: 283 KGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342 G P F+ + + + + AG T+S T +W L+ ++ H D V E+D++ G Sbjct: 236 TGTP--RFSADEITGMFISMMFAGHHTSSGTASWTLIELMRHRDAYAAVIDELDELYGDG 293 Query: 343 RRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSV 402 R +P V+ E R + + + + + EVQG RI +G + + + Sbjct: 294 RSVSFHALRQIPQLENVLKETLRLHPPL-IILMRVAKGEFEVQGHRIHEGDLVAASPAIS 352 Query: 403 LKDEAVWEKPFRFHPEHFLDAQ-GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLL 461 + + P F P + + + ++PF AGR C+G A M++ F+ LL Sbjct: 353 NRIPEDFPDPHDFVPARYEQPRQEDLLNRWTWIPFGAGRHRCVGAAFAIMQIKAIFSVLL 412 Query: 462 QHFSFSV--PTGQPRPSHHGVFAFLVSPS 488 + + F + P R H + L P+ Sbjct: 413 REYEFEMAQPPESYRNDHSKMVVQLAQPA 441 >3EJB-B nrPDB Length = 404 Score = 199 bits (505), Expect = 3e-51, Method: Composition-based stats. Identities = 70/418 (16%), Positives = 131/418 (31%), Gaps = 63/418 (15%) Query: 50 DFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVP--IT 107 +F PY F R ++ P + G A + R P+P T Sbjct: 10 EFLKNPYSFYDTLRAVHPIYKGSFLKYPGWYVTGYE--ETAAILKDARFKVRTPLPESST 67 Query: 108 QILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANH 167 + + L + P R R + +S + ++ E L Sbjct: 68 KYQDLSHVQNQMMLFQNQPDHRRLRTLASGAFTP--RTTESYQPYIIETVHHLLDQVQGK 125 Query: 168 SGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAV 227 + A VIA++ + + +E ++ + ++ + Sbjct: 126 KKMEVISDFAFPLASF-VIANI----------------IGVPEEDREQLKEWAASLIQTI 168 Query: 228 PVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPE 287 AL + +A EL+ + + P +D+ L KG + Sbjct: 169 DFTRSRKALTEGNIMAVQAM-AYFKELIQKRKR-----HPQQDMISMLL------KGREK 216 Query: 288 SSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEM 347 +E L AG TT ++ +L ++ HP+ ++++ D Sbjct: 217 DKLTEEEAASTCILLAIAGHETTVNLISNSVLCLLQHPEQLLKLRENPD----------- 265 Query: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407 + E R+ + + S DI++ G I +G + L + +D + Sbjct: 266 -------LIGTAVEECLRYESPTQM-TARVASEDIDICGVTIRQGEQVYLLLGAANRDPS 317 Query: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465 ++ P F P L F G CLG LAR+E + +LLQ Sbjct: 318 IFTNPDVFDITR---------SPNPHLSFGHGHHVCLGSSLARLEAQIAINTLLQRMP 366 >4KPA-A nrPDB Length = 494 Score = 194 bits (493), Expect = 7e-50, Method: Composition-based stats. Identities = 81/472 (17%), Positives = 163/472 (34%), Gaps = 29/472 (6%) Query: 32 RYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREAL 91 + P P L NL ++ ++ G++F + L+ ++EA Sbjct: 27 KEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEA- 85 Query: 92 VTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPA-WREQRRFSVSTLRNLGLGKKSLE 150 +++ + G+F + W++ + + + K Sbjct: 86 ---CDESRFDKNLSQALKFVRDFAGDGLFTSWTHEKNWKKAHNILLPSFSQQAM--KGYH 140 Query: 151 QWVTEEAACLCAAFANHSGRP-FRPNGLLDKAVSNVIASLTCGRRFE--YDDPRFLRLLD 207 + + A L + + + + + I RF Y D + Sbjct: 141 AMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITS 200 Query: 208 LAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQP 267 + ++ + ++ A P + K +D+++ + + + + Sbjct: 201 M----VRALDEAMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKAS---GEQ 253 Query: 268 PRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDV 327 DL L + G P +DEN+R + AG TTS L++ L ++ +P V Sbjct: 254 SDDLLTHMLNGKDPETGEP---LDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHV 310 Query: 328 QRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQG- 386 ++ +E V+ P + Y V++E R P D + G Sbjct: 311 LQKAAEEAARVLVDP-VPSYKQVKQLKYVGMVLNEALRLWPTAPAFSL-YAKEDTVLGGE 368 Query: 387 FRIPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLG 445 + + KG L+ + + +D+ +W + F PE F + + AF PF G+RAC+G Sbjct: 369 YPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSA--IPQHAFKPFGNGQRACIG 426 Query: 446 EPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR 497 + A E L +L+HF F T + P + + A + Sbjct: 427 QQFALHEATLVLGMMLKHFDFEDHTNYELDIKE---TLTLKPEGFVVKAKSK 475 >5CJE-A nrPDB Length = 393 Score = 193 bits (491), Expect = 1e-49, Method: Composition-based stats. Identities = 56/252 (22%), Positives = 87/252 (34%), Gaps = 35/252 (13%) Query: 234 PALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDE 293 P L + LDEL+ + R T + L ++ + + + + E Sbjct: 170 PTGGDAELAAYERLAAYLDELIDDKRSTA--------PADDLLGDLIRTRAEDDDRLSGE 221 Query: 294 NLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHM 353 LR + L AG TT + G+ ++ HPD ++ A M Sbjct: 222 ELRAMAFILLVAGHETTVNLITNGVHTLLTHPDQLAALR------------------ADM 263 Query: 354 PYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPF 413 + EV RF V + +E+ G I +G ++ L + +D A P Sbjct: 264 TLLDGAVEEVLRFEGPVETATYRYAAESMEIGGTAIAEGDPVMIGLDAAGRDPARHPDPH 323 Query: 414 RFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQP 473 F P+ L F G CLG PLAR+E + SLL+ G P Sbjct: 324 VFDIHR---------APQGHLAFGHGIHYCLGAPLARLEARVALRSLLERCPDLALDGPP 374 Query: 474 RPSHHGVFAFLV 485 G+ V Sbjct: 375 GARPPGMLIRGV 386 >5OFQ-A nrPDB Length = 409 Score = 190 bits (482), Expect = 1e-48, Method: Composition-based stats. Identities = 73/380 (19%), Positives = 121/380 (31%), Gaps = 58/380 (15%) Query: 115 RSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRP 174 R + + + + R + + LE + E A L S F Sbjct: 79 RQESILMMDPPKHTK-LRNLVNKAFTPRAI--QHLEGHIEEIADYLLDEV--SSKEKFDI 133 Query: 175 NGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIP 234 + ++ + G + D F + D G + S A ++ Sbjct: 134 VEDFAGPLPIIVIAELLGVPIQ-DRALFKKYSDDLVSGAENNSD------EAFAKMMQ-- 184 Query: 235 ALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDEN 294 K E++ E + DL L + +E Sbjct: 185 ----KRNEGVIFLQGYFKEIIAERQQ-----NKQEDLISLLLEAEIDGE-----HLTEEE 230 Query: 295 LRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMP 354 + L AG TT+ + G+ M DVQ V+++I V Sbjct: 231 VLGFCILLLVAGNETTTNLITNGVRYMTEDVDVQNEVRRDISLV---------------- 274 Query: 355 YTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFR 414 ++ E R+ + + + + D+E+ +I +G +I+ +S +D A +E P Sbjct: 275 --PNLVEETLRYYPPIQ-AIGRIAAEDVELGECKIKRGQQVISWAASANRDSAKFEWPDT 331 Query: 415 FHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPR 474 F K + F G CLG PLARME + FT LL+ FS Q Sbjct: 332 FVVHR---------KTNPHVSFGFGIHFCLGAPLARMEGKIAFTKLLEKGGFSKVQNQSL 382 Query: 475 PSHHGVFAFLVSPSPYELCA 494 F F V YE+ Sbjct: 383 KPIDSPFVFGV--KKYEIAF 400 >5VWS-A nrPDB Length = 393 Score = 190 bits (482), Expect = 1e-48, Method: Composition-based stats. Identities = 72/405 (17%), Positives = 130/405 (32%), Gaps = 69/405 (17%) Query: 67 DVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGP 126 V+ Q + + VR+ L + ++DR G G+ + P Sbjct: 32 PVWRDQFG---IYHVFRYDDVRQILGDYQTFSSDRTR---LMPTAQGFGKGGITMIDP-P 84 Query: 127 AWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVI 186 R QRR + ++E + + A L P D Sbjct: 85 EHRHQRRLITHAFTPQSIS--AMEPRIRQIADHLLDEL---------PGPEFDLV----- 128 Query: 187 ASLTCGRRFEYDDPRFL--RLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQ 244 F Y P + LL + + +++ P ++ R Sbjct: 129 ------EHFAYPLPVIVIAELLGVPPGDRHLFRTWSDRLMSLQVENYADP----ELARTV 178 Query: 245 KAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFS 304 A +T++++ L EH + P DL + + K + E + + L Sbjct: 179 AAAMTEMNDYLREHCRS-RRTHPRDDLLTRLVQAEVEGK-----RLDLEEVVNTASLLLL 232 Query: 305 AGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQ 364 AG +TT+ + +L + HP+ ++ V+ + A + E Sbjct: 233 AGHLTTTVLIGNTMLCLWDHPEAEKAVRADPS------------------LIPAALEESL 274 Query: 365 RFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQ 424 R L +T+RD+ + G IP ++ + S D+ + P RF Sbjct: 275 RLRSPF-LQAGRVTTRDVTIAGETIPANRFVMAWILSANHDDRRFPDPERFDLHR----- 328 Query: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVP 469 + + F G CLG L R+E + LL F+ P Sbjct: 329 ----QTTGHIAFGHGVHFCLGAQLGRLEGRIALERLLGRFTEIHP 369 >5L94-A nrPDB Length = 410 Score = 189 bits (481), Expect = 2e-48, Method: Composition-based stats. Identities = 59/387 (15%), Positives = 117/387 (30%), Gaps = 63/387 (16%) Query: 81 LNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLR 140 + V+E L ++DR P + G + P E R Sbjct: 49 VFHYDGVKEVLEQKNIFSSDRRPPQNQRQTALGTS----LINIDPPKHAEMRALVNKAFT 104 Query: 141 NLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDP 200 + K+ E + L + + + Sbjct: 105 PKAM--KAWEPKIARITNELLQEVEHLED-----------------IDIVEHLSYPLPVM 145 Query: 201 RFLRLLDLAQEGLKEESGFLREVLNAVPVLLH--IPALAGKVLRFQKAFLTQLDELLTEH 258 +L + E ++ + ++ + L + ++ T ++ E Sbjct: 146 VIADILGVPIEDQRQFKDWSDIIVAGPSNNERETLEKLQQEKMKANDELETYFYRIIEEK 205 Query: 259 RMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGL 318 R +P D+ L E+ K DE + L AG TT+ ++ + Sbjct: 206 R-----TRPGDDIISVLLQAKEEGK-----QLTDEEIVGFSILLLIAGNETTTNLISNTI 255 Query: 319 LLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMT 378 ++ R+++E + + I EV R+ V + + Sbjct: 256 YCLMEDKASFERLKREKE------------------LLPSGIEEVLRYRSPVQ-ALHRIV 296 Query: 379 SRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSA 438 D+ + G ++ G ++ + S +D +E P F + KP + F Sbjct: 297 KEDVTLAGKKLKAGEHVVPWMGSAHRDAEYFEDPEVFKIDR---------KPNVHMAFGR 347 Query: 439 GRRACLGEPLARMELFLFFTSLLQHFS 465 G CLG PLAR+E + L+ + Sbjct: 348 GIHFCLGAPLARIEAKIMLAELIDRYP 374 >3N9Z-A nrPDB Length = 487 Score = 188 bits (478), Expect = 4e-48, Method: Composition-based stats. Identities = 81/480 (16%), Positives = 152/480 (31%), Gaps = 46/480 (9%) Query: 35 PGPLPLPGLGNL-LHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93 PG L + Q +++G ++ +L V + V AL+ Sbjct: 14 PGDNGWLNLYHFWRETGTHKVHLHHVQNFQKYGPIYREKLGNVESVYVIDPEDV--ALLF 71 Query: 94 HGEDTADR----PPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSL 149 E PP + R GV L + W++ R + K L Sbjct: 72 KSEGPNPERFLIPPWVAYHQ--YYQRPIGVLLKKSAA-WKKDRVALNQEVMAPEATKNFL 128 Query: 150 EQWVTEEAACLCAAFAN------HSGRPFRPNGLLDKAVSNVIASLTCGRRFEYD----D 199 + + + + L + I ++ G R + Sbjct: 129 -PLLDAVSRDFVSVLHRRIKKAGSGNYSGDISDDLFRFAFESITNVIFGERQGMLEEVVN 187 Query: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLT--- 256 P R +D + +LN P L + K + A + Sbjct: 188 PEAQRFIDAIYQMFHT----SVPMLNLPPDLFRL--FRTKTWKDHVAAWDVIFSKADIYT 241 Query: 257 -----EHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTS 311 E R R + L +S + E+++ V ++ + G+ TTS Sbjct: 242 QNFYWELRQKGSVHHDYRGILYRLLG---------DSKMSFEDIKANVTEMLAGGVDTTS 292 Query: 312 TTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVP 371 TL W L M + VQ ++ E+ Q + +P A I E R I Sbjct: 293 MTLQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQLVPLLKASIKETLRLHPIS- 351 Query: 372 LGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPE 431 + + D+ ++ + IP T + + ++ ++ + P F P +L + Sbjct: 352 VTLQRYLVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDPENFDPTRWLSKDKNITY-F 410 Query: 432 AFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYE 491 L F G R CLG +A +E+ +F ++L++F + + + P + Sbjct: 411 RNLGFGWGVRQCLGRRIAELEMTIFLINMLENFRVEIQHLSDVGTTFNLILMPEKPISFT 470 >2VZM-A nrPDB Length = 436 Score = 187 bits (474), Expect = 1e-47, Method: Composition-based stats. Identities = 78/432 (18%), Positives = 127/432 (29%), Gaps = 82/432 (18%) Query: 91 LVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWR----EQRRFSVSTLRNLGLGK 146 L G+D A P P L + V W ++ R ++ R + Sbjct: 37 LGALGQDFAADP-YPTYARLRAEGPAHRVRTPEGNEVWLVVGYDRARAVLADPRFSKDWR 95 Query: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206 S EAA + R R L+ + RR E PR ++ Sbjct: 96 NSTTPLTEAEAALNHNMLESDPPRHTRLRKLVARE--------FTMRRVELLRPRVQEIV 147 Query: 207 DLAQEGLKEESGFLREVLNAVPVLLH--------------------------IPALAGKV 240 D + + +++ ++ L P + Sbjct: 148 DGLVDAMLAAPDGRADLMESLAWPLPITVISELLGVPEPDRAAFRVWTDAFVFPDDPAQA 207 Query: 241 LRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVA 300 L L+ R Q DL A + + S E L + Sbjct: 208 QTAMAEMSGYLSRLIDSKR-----GQDGEDLLSALV----RTSDEDGSRLTSEELLGMAH 258 Query: 301 DLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVI 360 L AG TT +A G+ ++ HPD ++ A M + Sbjct: 259 ILLVAGHETTVNLIANGMYALLSHPDQLAALR------------------ADMTLLDGAV 300 Query: 361 HEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHF 420 E+ R+ V +++ G IP G T++ L+ + + P RF Sbjct: 301 EEMLRYEGPVESATYRFPVEPVDLDGTVIPAGDTVLVVLADAHRTPERFPDPHRFDIRR- 359 Query: 421 LDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS---FSVPTGQ----P 473 L F G C+G PLAR+E + +LL+ V G+ P Sbjct: 360 --------DTAGHLAFGHGIHFCIGAPLARLEARIAVRALLERCPDLALDVSPGELVWYP 411 Query: 474 RPSHHGVFAFLV 485 P G+ A + Sbjct: 412 NPMIRGLKALPI 423 >5IT1-A nrPDB Length = 399 Score = 187 bits (474), Expect = 1e-47, Method: Composition-based stats. Identities = 76/404 (18%), Positives = 129/404 (31%), Gaps = 65/404 (16%) Query: 81 LNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLR 140 + G VR L + + +G L + P + R+ Sbjct: 48 VTGYEQVRAVLRDPSFSVGVPHALHTQDGVVTQKPGRGSLLWQDAPEHTDDRKLLAKEFT 107 Query: 141 NLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDP 200 + ++L + A G P V +++ S G E Sbjct: 108 VRRM--QALRPNIQRIVDEHLDAIEA-RGGPVDLVKTFANPVPSMVISDLFGVPAER-RA 163 Query: 201 RFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRM 260 F + + ++ + + L +L+ E R Sbjct: 164 EFQEIAEAMMRVDQDAAATEAAGMR---------------------LGGLLYQLVQERR- 201 Query: 261 TWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLL 320 A P DL A + +P+ +D L L A TT+ + G L Sbjct: 202 ----ANPGDDLISALIT-----TEDPDGVIDDMFLMNAAGTLLIAAHDTTACMIGLGTAL 252 Query: 321 MILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSR 380 ++ PD +Q++ + E+ R+ I G + ++ Sbjct: 253 LLDRPDQLALLQKDPS------------------LIGNAVEELLRYLTIGQFGAERVATQ 294 Query: 381 DIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGR 440 D E+ G RI KG ++T+L S D A E P RF +P L F G Sbjct: 295 DGEIGGVRIAKGEQVVTHLLSADFDPAFVEDPERFDITR---------RPAPHLAFGFGA 345 Query: 441 RACLGEPLARMELFLFFTSLLQHFS---FSVPTGQPRPSHHGVF 481 C+G+ LAR+EL + F +L + F + P + R + VF Sbjct: 346 HQCIGQQLARIELQIVFGTLFRRFPTLRLAKPVEELRFRNDMVF 389 >3A50-A nrPDB Length = 411 Score = 185 bits (470), Expect = 4e-47, Method: Composition-based stats. Identities = 80/396 (20%), Positives = 122/396 (30%), Gaps = 65/396 (16%) Query: 67 DVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGP 126 V L L PV +L A VREA V R +P Q + + P Sbjct: 34 PVRKLALPDGPVWLLTRYADVREAFVDPRLSKDWRHRLPEDQRADMPATPTPMMILMDPP 93 Query: 127 AWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRP-NGLLDKAVSNV 185 R+ + + LE +TE A L A P + V Sbjct: 94 DHTRLRKLVGRSFTVRRM--NELEPRITEIADGLLAGLPTD--GPVDLMREYAFQIPVQV 149 Query: 186 IASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQK 245 I LL L E + S + +++ P A Sbjct: 150 IC----------------ELLGLPAEDRDDFSAWSSVLVDDSP--------ADDKNAAMG 185 Query: 246 AFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSA 305 L +LL R D +A L+ + + E L + L A Sbjct: 186 KLHGYLSDLLERKRTEPD---------DALLSSLLAVSDMDGDRLSQEELVAMAMLLLIA 236 Query: 306 GMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQR 365 G TT + G+L ++ HPD ++ + ++ ++ + E R Sbjct: 237 GHETTVNLIGNGVLALLTHPDQRKLLAEDPS------------------LISSAVEEFLR 278 Query: 366 FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQG 425 F V T+ D+ G IP G ++ L++ +D +P R DA G Sbjct: 279 FDSPVSQAPIRFTAEDVTYSGVTIPAGEMVMLGLAAANRDADWMPEPDRLDITR--DASG 336 Query: 426 HFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLL 461 F G CLG LAR+E + L Sbjct: 337 GVF-------FGHGIHFCLGAQLARLEGRVAIGRLF 365 >3ABA-A nrPDB Length = 403 Score = 184 bits (468), Expect = 5e-47, Method: Composition-based stats. Identities = 75/404 (18%), Positives = 130/404 (32%), Gaps = 65/404 (16%) Query: 81 LNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLR 140 + G VR L + + +G L + P R+ Sbjct: 48 VTGYEEVRALLRDSSFSVQVPHALHTQDGVVTQKPGRGSLLWQDEPEHTSDRKLLAKEFT 107 Query: 141 NLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDP 200 + ++L + A G P AV +++ S G E Sbjct: 108 VRRM--QALRPNIQRIVDEHLDAIEA-RGGPVDLVKTFANAVPSMVISDLFGVPVER-RA 163 Query: 201 RFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRM 260 F + + ++ + + L +L+ E R Sbjct: 164 EFQDIAEAMMRVDQDAAATEAAGMR---------------------LGGLLYQLVQERR- 201 Query: 261 TWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLL 320 A P DL A + +P+ +D L L A TT+ + G L Sbjct: 202 ----ANPGDDLISALIT-----TEDPDGVVDDMFLMNAAGTLLIAAHDTTACMIGLGTAL 252 Query: 321 MILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSR 380 ++ PD ++++ V + E+ R+ I G + +R Sbjct: 253 LLDSPDQLALLREDPSLV------------------GNAVEELLRYLTIGQFGGERVATR 294 Query: 381 DIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGR 440 D+E+ G RI KG ++ ++ + D A E+P RF +P L F G Sbjct: 295 DVELGGVRIAKGEQVVAHVLAADFDPAFVEEPERFDITR---------RPAPHLAFGFGA 345 Query: 441 RACLGEPLARMELFLFFTSLLQHFS---FSVPTGQPRPSHHGVF 481 C+G+ LAR+EL + F +L + + P + R H VF Sbjct: 346 HQCIGQQLARIELQIVFETLFRRLPGLRLAKPVEELRFRHDMVF 389 >2Y5N-A nrPDB Length = 417 Score = 182 bits (463), Expect = 2e-46, Method: Composition-based stats. Identities = 67/387 (17%), Positives = 122/387 (31%), Gaps = 66/387 (17%) Query: 81 LNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLR 140 + VR L P + + +G L+ P RR V Sbjct: 66 VTRYEDVRAVLGD--GRFVRGPSMTRDEPRTRPEMVKGGLLSMDPPEHSRLRRLVVKAFT 123 Query: 141 NLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDK-AVSNVIASLTCGRRFEYDD 199 +SL E A L A G+P + + VI Sbjct: 124 --ARRAESLRPRAREIAHELVDQMAAT-GQPADLVAMFARQLPVRVIC------------ 168 Query: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHR 259 L + + SG A ++ + + +L+ R Sbjct: 169 -ELLGVPSADHDRFTRWSGAFLSTAE---------VTAEEMQEAAEQAYAYMGDLIDRRR 218 Query: 260 MTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLL 319 +P DL A + + + S +++ L + L AG +T+T +A + Sbjct: 219 K-----EPTDDLVSALVQAR-----DQQDSLSEQELLDLAIGLLVAGYESTTTQIADFVY 268 Query: 320 LMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDI-VPLGVTHMT 378 L++ P+++R++ + + + E+ R+ + V Sbjct: 269 LLMTRPELRRQLLDRPE------------------LIPSAVEELTRWVPLGVGTAFPRYA 310 Query: 379 SRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSA 438 D+ ++G I G ++ + + +D+A + R + P L F Sbjct: 311 VEDVTLRGVTIRAGEPVLASTGAANRDQAQFPDADRIDVDR---------TPNQHLGFGH 361 Query: 439 GRRACLGEPLARMELFLFFTSLLQHFS 465 G CLG PLAR+EL + LLQ Sbjct: 362 GVHHCLGAPLARVELQVALEVLLQRLP 388 >4OQS-A nrPDB Length = 433 Score = 181 bits (460), Expect = 4e-46, Method: Composition-based stats. Identities = 79/421 (18%), Positives = 138/421 (32%), Gaps = 87/421 (20%) Query: 81 LNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAW------REQRRF 134 + AA R ++ ++RP + G P W E R+ Sbjct: 50 VTSHAAARTVMID--PRFSNRPE--HKHPVFSVIPRPGGATKAPAPGWFINMDAPEHTRY 105 Query: 135 SVSTLRNLGLGK-KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGR 193 + + + K LE + + A A +G P V +++ + Sbjct: 106 RRMLISQFTVRRIKELEPRIVQITEDHLDAMAK-AGPPVDLVQAFALPVPSLV--ICELL 162 Query: 194 RFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDE 253 Y D F QE + + +V + E Sbjct: 163 GVSYADHAF------FQEQTTIMASVDKT--------------QDEVTTALGKLTRYIAE 202 Query: 254 LLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTT 313 L+ R++ P DL + + ++ DE L + L AG TT+ Sbjct: 203 LVATKRLS-----PKDDLLGSLIT---------DTDLTDEELTNIALLLLVAGHETTANM 248 Query: 314 LAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLG 373 L G ++ HP+ + + E+ R+ IV LG Sbjct: 249 LGLGTFALLQHPEQIAALDS-----------------------PDAVEELLRYLSIVHLG 285 Query: 374 VT-HMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEA 432 D+E++G I KG T+ L +V +D V+++P + + Sbjct: 286 TPNRAALEDVELEGQMIRKGDTVAIGLPAVNRDPKVFDEPDILQLDRVDARK-------- 337 Query: 433 FLPFSAGRRACLGEPLARMELFLFFTSLLQHFS---FSVPTGQ----PRPSHHGVFAFLV 485 F G CLG+ LAR+E+ + FT L F +VP + + + +GV+A V Sbjct: 338 HAAFGGGIHQCLGQQLARVEMRIGFTRLFARFPSLRLAVPAEEIKLREKSAAYGVWALPV 397 Query: 486 S 486 + Sbjct: 398 A 398 >4OQR-A nrPDB Length = 457 Score = 181 bits (459), Expect = 6e-46, Method: Composition-based stats. Identities = 77/421 (18%), Positives = 138/421 (32%), Gaps = 87/421 (20%) Query: 81 LNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAW------REQRRF 134 + AA R ++ ++RP + G P W E R+ Sbjct: 89 VTSHAAARTVMID--PRFSNRPE--HKHPVFSVIPRPGGATKAPAPGWFTNMDAPEHTRY 144 Query: 135 SVSTLRNLGLGK-KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGR 193 + + + K LE + A A +G P V +++ + Sbjct: 145 RRMLISQFTVRRIKELEPRIVRITEDHLDAMAK-AGPPVDLVQAFALPVPSLV--ICELL 201 Query: 194 RFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDE 253 Y D F + +++ + +V + E Sbjct: 202 GVSYADHAFFQ--------------------EQTTIMVSVDKTQDEVTTALGKLTRYIAE 241 Query: 254 LLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTT 313 L+ R++ P DL + + ++ DE L + L AG TT+ Sbjct: 242 LVATKRLS-----PKDDLLGSLIT---------DTDLTDEELTNIALILLVAGHETTANM 287 Query: 314 LAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLG 373 L G ++ HP+ + + E+ R+ IV LG Sbjct: 288 LGLGTFALLQHPEQIANLDS-----------------------PDAVEELLRYLSIVHLG 324 Query: 374 VT-HMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEA 432 D+E++G I KG T+ L +V +D V+++P + + Sbjct: 325 TPNRAALEDVELEGQMIRKGDTVAIGLPAVNRDPKVFDEPDILQLDRVDARK-------- 376 Query: 433 FLPFSAGRRACLGEPLARMELFLFFTSLLQHFS---FSVPTGQ----PRPSHHGVFAFLV 485 F G CLG+ LAR+E+ + FT L F +VP + + + +GV+A V Sbjct: 377 HAAFGGGIHQCLGQQLARVEMRIGFTRLFARFPSLRLAVPAEEIKLREKSAAYGVWALPV 436 Query: 486 S 486 + Sbjct: 437 A 437 >3MZS-A nrPDB Length = 486 Score = 181 bits (459), Expect = 6e-46, Method: Composition-based stats. Identities = 79/452 (17%), Positives = 148/452 (32%), Gaps = 40/452 (8%) Query: 63 RRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLA 122 +++G ++ +L V + V G P + + GV Sbjct: 45 QKYGPIYREKLGNLESVYIIHPEDVAHLFKFEGSYPERYDIPPWLAYHRYYQKPIGVLFK 104 Query: 123 RYGPAWREQRR------FSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPF--RP 174 + G W++ R + ++N L + + L F Sbjct: 105 KSG-TWKKDRVVLNTEVMAPEAIKNF---IPLLNPVSQDFVSLLHKRIKQQGSGKFVGDI 160 Query: 175 NGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIP 234 L I ++ G R + + + + +LN P L + Sbjct: 161 KEDLFHFAFESITNVMFGERLGMLEETVNPEAQKFIDAVYKMFHTSVPLLNVPPELYRL- 219 Query: 235 ALAGKVLRFQKAFLTQLDELLTE---------HRMTWDPAQPPRDLTEAFLAEMEKAKGN 285 K R A + + R T P + L Sbjct: 220 -FRTKTWRDHVAAWDTIFNKAEKYTEIFYQDLRRKTEFRNYPG--ILYCLLKS------- 269 Query: 286 PESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP 345 E+++ + ++ + G+ TTS TL W L M +VQ +++E+ + Q Sbjct: 270 --EKMLLEDVKANITEMLAGGVNTTSMTLQWHLYEMARSLNVQEMLREEVLNARRQAEGD 327 Query: 346 EMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKD 405 +P A I E R I + + D+ +Q + IP T + + ++ +D Sbjct: 328 ISKMLQMVPLLKASIKETLRLHPIS-VTLQRYPESDLVLQDYLIPAKTLVQVAIYAMGRD 386 Query: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465 A + P +F P +L + L F G R C+G +A +E+ LF +L++F Sbjct: 387 PAFFSSPDKFDPTRWLSKDKDLIH-FRNLGFGWGVRQCVGRRIAELEMTLFLIHILENFK 445 Query: 466 FSVPTGQPRPSHHGVFAFLVSP-SPYELCAVP 496 + Q +F +++P P L P Sbjct: 446 VEM---QHIGDVDTIFNLILTPDKPIFLVFRP 474 >4RM4-A nrPDB Length = 396 Score = 178 bits (451), Expect = 5e-45, Method: Composition-based stats. Identities = 70/427 (16%), Positives = 133/427 (31%), Gaps = 81/427 (18%) Query: 39 PLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDT 98 P P ++ ++ P FD+ + V+S+ L V++ + Sbjct: 26 PFPWYESM----RKDAPVSFDEENQ----VWSVFL----------YDDVKKVVGDK---- 63 Query: 99 ADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAA 158 + + R + K E + E Sbjct: 64 ---ELFSSCMPQQTSSIGNSIINMDPPKHTK-IRSVVNKAFTPRVM--KQWEPRIQEITD 117 Query: 159 CLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESG 218 L F F + ++ S G + + +F DL K++S Sbjct: 118 ELIQKFQGR--SEFDLVHDFSYPLPVIVISELLGVPSAHME-QFKAWSDLLVSTPKDKSE 174 Query: 219 FLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAE 278 + A + + ++ ++ E R +P +D+ + Sbjct: 175 EAEK------------AFLEERDKCEEELAAFFAGIIEEKRN-----KPEQDIISILVEA 217 Query: 279 MEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDV 338 E + + E L L AG TT+ ++ + ++ P V ++ Sbjct: 218 EETGE-----KLSGEELIPFCTLLLVAGNETTTNLISNAMYSILETPGVYEELR------ 266 Query: 339 IGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITN 398 +H + E RF P+ + + RD E+ G I +G ++ Sbjct: 267 ------------SHPELMPQAVEEALRFRAPAPV-LRRIAKRDTEIGGHLIKEGDMVLAF 313 Query: 399 LSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFT 458 ++S +DEA +++P F P + F G CLG PLAR+E + T Sbjct: 314 VASANRDEAKFDRPHMFDIRRH---------PNPHIAFGHGIHFCLGAPLARLEANIALT 364 Query: 459 SLLQHFS 465 SL+ F Sbjct: 365 SLISAFP 371 >4GGV-A nrPDB Length = 418 Score = 178 bits (451), Expect = 6e-45, Method: Composition-based stats. Identities = 84/443 (18%), Positives = 132/443 (29%), Gaps = 73/443 (16%) Query: 47 LHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPI 106 L +P FD+ + V+++ + +LN L + Sbjct: 38 LRGQRPESPVVFDETQ----GVWNVYGYPEAMDILNDHDTFTSDLAH------------L 81 Query: 107 TQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFAN 166 + P +G P R+ R+ + +E V + L A Sbjct: 82 LPVSVDAPLLEGDMSQMDPPRHRKYRQLVSRAFTPRLVAD--METRVADITRELLDAV-- 137 Query: 167 HSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNA 226 G+P VI D F + D EG + Sbjct: 138 -DGKPEIEIAADLAYPLPVIVIAELLGVPAGDRDLFKKWADDIIEGFSG--------FSF 188 Query: 227 VPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNP 286 + + L + +TE R T E L + +A+ + Sbjct: 189 LDTSGQGEQDVRDATERLRPLLDYMAGHVTERRRTPR---------EDLLTHLVQAEVDG 239 Query: 287 ESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPE 346 E D + V L G +TT+ TL +L + P+V +V+ + V G Sbjct: 240 E-RLTDNEIVNVANILLVTGHITTTMTLGNTVLCLDADPEVAAKVRADRSLVPG------ 292 Query: 347 MGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDE 406 I E R + TSR++EV G IPK ++ L + +D Sbjct: 293 ------------AIEEALRVLSPSA-ALARGTSREVEVAGTVIPKDQIVMLWLGAGNRDP 339 Query: 407 AVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSF 466 + P + P P F G CLG PLAR+E + +L F Sbjct: 340 RQFTDPEVYDPTR---------DPNPHFGFGRGIHFCLGAPLARLEGRVALNALFDRFPV 390 Query: 467 SV------PTGQPRPSHHGVFAF 483 PT P P GV Sbjct: 391 LRTDPAKPPTFFPTPDMIGVNTL 413 >1Z8P-A nrPDB Length = 404 Score = 178 bits (451), Expect = 6e-45, Method: Composition-based stats. Identities = 64/409 (15%), Positives = 130/409 (31%), Gaps = 73/409 (17%) Query: 67 DVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQI-----LGFGPRSQGVFL 121 V ++ ++ G + AL + + P ++ LGF + F Sbjct: 28 PVTPVRFLGQDAWLVTGYDEAKAALSDLRLSSDPKKKYPGVEVEFPAYLGFPEDVRNYFA 87 Query: 122 ARYG----PAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGL 177 G P R+ + +++ V + A L Sbjct: 88 TNMGTSDPPTHTRLRKLVSQEFTVRRV--EAMRPRVEQITAELLDEV--GDSGVVDIVDR 143 Query: 178 LDK-AVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPAL 236 VI LL + ++ E + E +L+ P Sbjct: 144 FAHPLPIKVIC----------------ELLGVDEKYRGEFGRWSSE------ILVMDPER 181 Query: 237 AGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLR 296 A + + + + + +L+ R +P DL A + + + + + + + L Sbjct: 182 AEQRGQAAREVVNFILDLVERRR-----TEPGDDLLSALI----RVQDDDDGRLSADELT 232 Query: 297 IVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYT 356 + L AG ++ + + G L++ HPD V+++ Sbjct: 233 SIALVLLLAGFESSVSLIGIGTYLLLTHPDQLALVRRDPSA------------------L 274 Query: 357 TAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFH 416 + E+ R+ P T + ++E+ G IP+ +T++ + +D + P RF Sbjct: 275 PNAVEEILRYIAP-PETTTRFAAEEVEIGGVAIPQYSTVLVANGAANRDPKQFPDPHRFD 333 Query: 417 PEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465 L F G C+G PLA++E + +L F Sbjct: 334 VTR---------DTRGHLSFGQGIHFCMGRPLAKLEGEVALRALFGRFP 373 >6A7J-A nrPDB Length = 411 Score = 178 bits (451), Expect = 6e-45, Method: Composition-based stats. Identities = 74/424 (17%), Positives = 128/424 (30%), Gaps = 78/424 (18%) Query: 66 GDVFSLQL-AWTPVVVLNGLAAVREALVTHGEDTAD--------RPPVPITQILGFGPRS 116 G + ++L V + R AL+T D R +P L Sbjct: 26 GPLAEVELPGGVHVYAVTHHKEAR-ALLTDSRVVKDINVWNAWQRGEIPADWPLIGLVNP 84 Query: 117 QGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANH-SGRPFRPN 175 L GP R R L + L + A +G P Sbjct: 85 GRSMLTVDGPDHRRLRTLVAQALTV--KRVEKLRAGIEALTNASLERLAALPAGEPVDLK 142 Query: 176 GLLDK-AVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIP 234 NVI+ E + ++ + Sbjct: 143 AEFAYPLPMNVIS-----------------------ELMGVDAADHPRLKELFEKFFSTQ 179 Query: 235 ALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDEN 294 +V + T +++ E + A P DLT A +A E DE Sbjct: 180 TPPEEVPQMMADLGTLFTKIVEEKK-----ANPGDDLTSALIAASEDG-----DHLTDEE 229 Query: 295 LRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMP 354 + + + +AG TT + + + + +HP+ +++V +P Sbjct: 230 ILNTLQLIIAAGHETTISLIVNVVEALAIHPEQRKKVLS-----------------GEIP 272 Query: 355 YTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVW-EKPF 413 + VI E R+ + + DIEV +PKG L+ + ++ +DE + Sbjct: 273 W-EGVIEETLRWNTPTSHVLIRFATEDIEVGDKVLPKGEGLVVSFGALGRDEEQYGPTAG 331 Query: 414 RFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF---SFSVPT 470 F P + F G C G L+R+E + +L + F +VP Sbjct: 332 DFDATR---------TPNRHIAFGHGPHVCPGAALSRLEAGIALPALYERFPELDLAVPA 382 Query: 471 GQPR 474 + R Sbjct: 383 AELR 386 >4UBS-A nrPDB Length = 393 Score = 177 bits (450), Expect = 7e-45, Method: Composition-based stats. Identities = 83/421 (19%), Positives = 131/421 (31%), Gaps = 74/421 (17%) Query: 75 WTPVVVLNGLAAVREALVTHGEDTADR--PPVPITQILGFGPRSQGVFL-ARYGPAWREQ 131 V V+ G AA R L ++DR P P T R++ V L P R Q Sbjct: 36 GRSVWVVTGHAAARALLSDQ-RLSSDRTLPRFPATTERFEAVRTRRVALLGVDDPEHRTQ 94 Query: 132 RRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDK-AVSNVIASLT 190 RR V + +L + E L A G P S VI +L Sbjct: 95 RRMLVPSFTL--KRAAALRPRIQETVDGLLDAMEA-QGPPAELVSAFALPLPSMVICAL- 150 Query: 191 CGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQ 250 Y D F R +L + +V + Sbjct: 151 --LGVPYADHDFFE-------------SQSRRLLRGPGI--------AEVQDARAQLDDY 187 Query: 251 LDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTT 310 L L+ R +P L + + E + + L + L AG TT Sbjct: 188 LYALIDRKRK-----EPGDGLLDDLIQEQL-----NRGTVDRAELVSLATLLLIAGHETT 237 Query: 311 STTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIV 370 + ++ G ++ HP+ ++ E A + E+ RF I Sbjct: 238 ANMISLGTFTLLRHPEQLAELRAEPG------------------LMPAAVEELLRFLSIA 279 Query: 371 PLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKP 430 G+ + + DIEV G I ++ S + +D A + +P Sbjct: 280 D-GLLRVATEDIEVAGTTIRADEGVVFATSVINRDAAGFAEPDALDWHR---------SA 329 Query: 431 EAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS---FSVPTGQ-PRPSHHGVFAFLVS 486 + F G CLG+ LAR E+ + +L + + P + P + L Sbjct: 330 RHHVAFGFGIHQCLGQNLARAEMEIALGTLFERLPGLRLAAPADEIPFKPGDTIQGMLEL 389 Query: 487 P 487 P Sbjct: 390 P 390 >2Z36-A nrPDB Length = 413 Score = 177 bits (449), Expect = 9e-45, Method: Composition-based stats. Identities = 77/445 (17%), Positives = 138/445 (31%), Gaps = 75/445 (16%) Query: 54 TPYCFDQLRRRFGDVFSLQL--AWTPVVVLNGLAAVREALVT-HGEDTADRPPVPITQ-- 108 P +++LR R + ++L V +G R L + P+ Sbjct: 24 PPAAYERLRER-APINKVRLTSGGQAWWV-SGHEEARAVLADGRFSSDKRKDGFPLFTLD 81 Query: 109 --ILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFAN 166 L + L G RR + L +L + + Sbjct: 82 AATLQQLRSQPPLMLGMDGAEHSAARRPVIGEFTVKRLA--ALRPRIQDIVDHFIDDMLA 139 Query: 167 HSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNA 226 RP L V +++ + Y D F + Sbjct: 140 TDQRPVDLVQALSLPVPSLV--ICELLGVPYTDHDF---------------------FQS 176 Query: 227 VPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNP 286 ++ R +D+L+T ++P DL +A + Sbjct: 177 RTTMMVSRTSMEDRRRAFAELRAYIDDLITRK-----ESEPGDDLFSRQIA-----RQRQ 226 Query: 287 ESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPE 346 E + + L + L +AG TT+ ++ G++ ++ HP+ V+ Sbjct: 227 EGTLDHAGLVSLAFLLLTAGHETTANMISLGVVGLLSHPEQLTVVKANPGR--------- 277 Query: 347 MGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDE 406 T + E+ R+ I + + + D+E+ G I G +I ++ S D Sbjct: 278 ---------TPMAVEELLRYFTIADGVTSRLATEDVEIGGVSIKAGEGVIVSMLSANWDP 328 Query: 407 AVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQH--- 463 AV++ P E L F G CLG+ LARMEL + F +L + Sbjct: 329 AVFKDPAVLDVER---------GARHHLAFGFGPHQCLGQNLARMELQIVFDTLFRRIPS 379 Query: 464 FSFSVPTGQ-PRPSHHGVFAFLVSP 487 +VP P ++ P Sbjct: 380 LRLAVPMEDVPFKGDSVIYGVHELP 404 >5NWS-A nrPDB Length = 435 Score = 176 bits (446), Expect = 2e-44, Method: Composition-based stats. Identities = 70/446 (15%), Positives = 130/446 (29%), Gaps = 75/446 (16%) Query: 45 NLLHVDFQNTPYCFDQLRRRFGDVFSLQL-AWTPVVVLNGLAAVREALVT---------- 93 +++ D P+ R G V + TPV + VR L Sbjct: 26 HMMDPDLLADPFTGYGRLRERGPVVRGRFVDGTPVWFVTRYDDVRAVLRDPRFVNTPSPV 85 Query: 94 --HGEDTADRPPVPITQILGFGPRSQ-GVFLARYGPAWREQRRFSVSTLRNLGLGKKSLE 150 G + + + G L P RR + L Sbjct: 86 PGEGGADPREGMMDLLNVPEPLRVYLLGSILDSDPPDHPRLRRLVTRAFAARRIL--GLR 143 Query: 151 QWVTEEAACLCAAF--ANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208 + A L A +S I + L+ + Sbjct: 144 PGIERIADRLLAELPRREEEDGTVDLLEHFAYPLS--ITVIC-------------ELVGI 188 Query: 209 AQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPP 268 L+ + ++++ P L + L+ + R Sbjct: 189 PATDLERWREWGGDLVSMRPERLRHSFPV---------MIDYCHRLIEQRRAA------- 232 Query: 269 RDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQ 328 LT+ L+E+ +A+ + +D ++ L AG T++ + G ++ HP Sbjct: 233 --LTDDLLSELIRAQDDDGGRLSDIETVTMILTLVLAGHETSAHLIGNGTAALLTHPGQW 290 Query: 329 RRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFR 388 ++++ +HE+ R+ V + + D+E+ G Sbjct: 291 ALLRKDPA------------------LLPRAVHELMRWCGSVHVARLRYATEDLELAGTP 332 Query: 389 IPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPL 448 + +G + L S D + P R + Q E + F G CLG L Sbjct: 333 VARGDAVQLVLVSANFDPRHYSDPDRLDITRHQEGQA-----ENHVGFGHGIHYCLGATL 387 Query: 449 ARMELFLFFTSLLQHF-SFSVPTGQP 473 AR E + LL+ + ++ G P Sbjct: 388 ARQEGEVALARLLETYPDLALADGDP 413 >4YZR-A nrPDB Length = 405 Score = 176 bits (445), Expect = 2e-44, Method: Composition-based stats. Identities = 59/364 (16%), Positives = 114/364 (31%), Gaps = 62/364 (17%) Query: 121 LARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDK 180 LA+ P R + ++L + + A L + Sbjct: 92 LAKDTPDHTRLRSLVHQAFTPRTI--ENLRGSIEQIAEQLLDEMEKENKADI-MKSFASP 148 Query: 181 AVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKV 240 VI+ L+ + +E + + +++ + Sbjct: 149 LPFIVIS----------------ELMGIPKEDRSQFQIWTNAMVDTSEGNRELTN----- 187 Query: 241 LRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVA 300 + + F + +L+ + R +P DL + E S +++ L ++ Sbjct: 188 -QALREFKDYIAKLIHDRR-----IKPKDDLISKLVHAEE-----NGSKLSEKELYSMLF 236 Query: 301 DLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVI 360 L AG+ TT L G L ++ H +++Q+ + + + Sbjct: 237 LLVVAGLETTVNLLGSGTLALLQHKKECEKLKQQPEMIA------------------TAV 278 Query: 361 HEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHF 420 E+ R+ V + D +G I +G + + S +D +E P + Sbjct: 279 EELLRYTSPVVMMANRWAIEDFTYKGHSIKRGDMIFIGIGSANRDPNFFENPEILNINR- 337 Query: 421 LDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGV 480 P + F G CLG PLAR+E + F +LL+ F P Sbjct: 338 --------SPNRHISFGFGIHFCLGAPLARLEGHIAFKALLKRFPDIELAVAPDDIQWRK 389 Query: 481 FAFL 484 FL Sbjct: 390 NVFL 393 >2WIO-A nrPDB Length = 431 Score = 175 bits (444), Expect = 3e-44, Method: Composition-based stats. Identities = 78/393 (19%), Positives = 124/393 (31%), Gaps = 60/393 (15%) Query: 107 TQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFAN 166 T+++ + G+ P R R+ S + LE + + L A Sbjct: 94 TRVIEGASPTPGMIHEIDPPEHRALRKVVSSAFTPRTISD--LEPRIRDVTRSLLA---- 147 Query: 167 HSGRPFRPNGLL-DKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLN 225 +G F +L ++A L L + E + SG L ++ Sbjct: 148 DAGESFDLVDVLAFPLPVTIVA-------------ELLGLPPMDHEQFGDWSGALVDIQM 194 Query: 226 AVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGN 285 P PALA ++ L E R A P DL + + Sbjct: 195 DDPT---DPALAERIADVLNPLTAYLKARCAERR-----ADPGDDLISRLVLAEVDGR-- 244 Query: 286 PESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP 345 + +DE L AG +TT+ L + + HP ++ + Sbjct: 245 ---ALDDEEAANFSTALLLAGHITTTVLLGNIVRTLDEHPAHWDAAAEDPGRI------- 294 Query: 346 EMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKD 405 A++ EV R+ P + T++ EV G IP + T + S +D Sbjct: 295 -----------PAIVEEVLRYRPPFP-QMQRTTTKATEVAGVPIPADVMVNTWVLSANRD 342 Query: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF- 464 + P RF P L F G CLG PLAR+E + ++ F Sbjct: 343 SDAHDDPDRFDPSRKSGGAAQ-------LSFGHGVHFCLGAPLARLENRVALEEIIARFG 395 Query: 465 SFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR 497 +V R H P + PR Sbjct: 396 RLTVDRDDERLRHFEQIVLGTRHLPVLAGSSPR 428 >6GMF-A nrPDB Length = 397 Score = 174 bits (440), Expect = 1e-43, Method: Composition-based stats. Identities = 66/394 (16%), Positives = 121/394 (30%), Gaps = 61/394 (15%) Query: 72 QLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQI-LGFGPRSQGVFLARYGPAWRE 130 +L + + V L + ++R + + + P + Sbjct: 31 RLQPQGFMAVGRYQDVARVLHD-AKGFSNRGWAASLPRGVKWDTSMPPSIVQVDPPRHGK 89 Query: 131 QRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLT 190 R + + LE + + A L S + VIA Sbjct: 90 LRTLVTKAFTPRTVAQ--LEPRIRDIAHELVDGLRGKSTFEATV-EVTVPMPMIVIA--- 143 Query: 191 CGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQ 250 +L +A E + + +++ ++ ++ A ++ R + F Sbjct: 144 -------------EMLGVAPERRADFKRWSDDMVGSLALVRV--GNAAQLERSTQEFYAY 188 Query: 251 LDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTT 310 E+L +P DL LA + + L AG TT Sbjct: 189 FSEVLE-----ERRREPREDLISQLLAAEVDGE-----KLTAGEVLSFANTLLIAGNETT 238 Query: 311 STTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIV 370 ++ + L+ + HP+ Q A + AV+ EV R+ Sbjct: 239 TSLIGNALVALTDHPEQLAAAQ------------------ADLSLVPAVVEEVLRYESPA 280 Query: 371 PLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKP 430 + T D+E+ RIP + ++ L+S +DE+ + P RF Sbjct: 281 QC-IFRQTMTDVEIGDERIPARSVVLPLLASANRDESRFPDPDRFDIHRDTKG------- 332 Query: 431 EAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 L F C+G PLAR+E + LL Sbjct: 333 --HLAFGLDIHFCIGAPLARLEAKVMLEVLLARL 364 >6GK6-A nrPDB Length = 411 Score = 173 bits (439), Expect = 1e-43, Method: Composition-based stats. Identities = 80/421 (19%), Positives = 129/421 (30%), Gaps = 73/421 (17%) Query: 78 VVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWR----EQRR 133 V +L +R+ D R P++ F Q + A R QR Sbjct: 54 VELLKDPRLIRDF--RKLPDEVRRRYFPLSDRTTF--MDQHMLDADPPDHTRLRAIVQRA 109 Query: 134 FSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGR 193 FS + + L + E A L A ++D+ +IA Sbjct: 110 FSPRMM-------EGLRPRIQEIADGLIDA-------------VIDRRRMELIADFAF-- 147 Query: 194 RFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDE 253 P ++ E+ G R + + + F Sbjct: 148 ------PLPTAVIAELLGLPVEDRGRFRRWTKILLAPAKDREFVERAQPVVEEFAAYFRA 201 Query: 254 LLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTT 313 L R P DL L E+ + L +V L AG TT Sbjct: 202 LADARRKA-----PRDDLISGLLLAEEQEH-----KLSPAELSSMVFLLLVAGHETTVHL 251 Query: 314 LAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLG 373 +A G+LL++ HP +RR+ ++ V + + E R L Sbjct: 252 IASGMLLLLSHPAERRRLDEDPGLV------------------GSAVEEALRCEGPAELS 293 Query: 374 VTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAF 433 + DIE+ G R+P G + L + +D + P RF P Sbjct: 294 TIRWSLEDIELFGARVPAGEGVAAGLLAANRDPQHFPDPDRFDIGR---------SPNRH 344 Query: 434 LPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELC 493 + F G CLG LAR+E + F++LL+ R + + P+ + Sbjct: 345 IGFGGGIHFCLGAMLARIEAAIAFSTLLRRLPRIELATSTRDIVWSEWPTIRGPAAVPVV 404 Query: 494 A 494 Sbjct: 405 F 405 >5YSW-A nrPDB Length = 441 Score = 173 bits (438), Expect = 2e-43, Method: Composition-based stats. Identities = 80/448 (17%), Positives = 139/448 (31%), Gaps = 77/448 (17%) Query: 53 NTPYCFDQLRRRFGDVFSLQLA-WTPVVVLNGLAAVREALVT---HGEDTADRPPVPIT- 107 + P + R G V LA P +++G R L + P Sbjct: 52 HVPPALVAVSER-GPVARATLAAGDPFWLVSGYEEARAVLSDPRFSSDRFQYHPWFKELS 110 Query: 108 ----QILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAA 163 + L G F+ P R+ + + L + E A A Sbjct: 111 PEFRERLRDDKARAGSFINMDPPEHTRYRKLLTGQFTVRRI--RELGARIDEIVAGRVDA 168 Query: 164 FANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREV 223 A S +I L G R+E D F + Sbjct: 169 MLAGGTTADLMTEFAFPAPSLMICEL-LGVRYE-DRAEFQQ------------------- 207 Query: 224 LNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAK 283 LL + A + ++ A + L+T+ R A P D+ + Sbjct: 208 --RASALLQMNAPVAEAVKNADALRAFMQALVTDKR-----ANPAGDIISGLIHHA---- 256 Query: 284 GNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVR 343 + + D+ L + L AG TT++ L G+ +++ P ++ + + Sbjct: 257 -GADPALTDDELINIANLLLIAGYDTTASMLGLGIFVLLQRPAQLATLRDDPSRIAD--- 312 Query: 344 RPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVL 403 + E+ R+ +V G+ D+E G IP G+T++ ++ + Sbjct: 313 ---------------AVEELLRYLSVVNPGIFRFAKEDLEFAGEHIPAGSTVVVSVVATN 357 Query: 404 KDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQH 463 +D W P L F G CLG+ LARME+ + LL+ Sbjct: 358 RDARHWPDPD-LDLTR---------PRGPHLAFGHGVHQCLGQQLARMEMQAGYAELLRR 407 Query: 464 FS---FSVPTGQ-PRPSHHGVFAFLVSP 487 +VP + P + + P Sbjct: 408 LPNVRLAVPPEEVPLRNDMLTYGVHSLP 435 >3R9C-A nrPDB Length = 418 Score = 173 bits (438), Expect = 2e-43, Method: Composition-based stats. Identities = 53/238 (22%), Positives = 84/238 (35%), Gaps = 38/238 (15%) Query: 236 LAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENL 295 L + ++ L L+ E R T P DL +A ++ + Sbjct: 197 LFDEQMKAGMWLRDYLRALIDERRRT-----PGEDLMSGLVA-----VEESGDQLTEDEI 246 Query: 296 RIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPY 355 L AG TT +A L M+ P + + Sbjct: 247 IATCNLLLIAGHETTVNLIANAALAMLRTPGQWAALAADGSR------------------ 288 Query: 356 TTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRF 415 +AVI E R+ V L V+ D+ + +PKG T++ L++ +D + P RF Sbjct: 289 ASAVIEETMRYDPPVQL-VSRYAGDDLTIGTHTVPKGDTMLLLLAAAHRDPTIVGAPDRF 347 Query: 416 HPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQP 473 P+ L F G CLG PLAR+E + +L F + +G+P Sbjct: 348 DPDR---------AQIRHLGFGKGAHFCLGAPLARLEATVALPALAARFPEARLSGEP 396 >6A7I-A nrPDB Length = 411 Score = 172 bits (436), Expect = 3e-43, Method: Composition-based stats. Identities = 75/424 (17%), Positives = 129/424 (30%), Gaps = 78/424 (18%) Query: 66 GDVFSLQL-AWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARY 124 G + ++L V + A R AL+T D + + LA Sbjct: 26 GPLAEVELPGGVHVYAVTRHAEAR-ALLTDSRVVKDIDVWNAWRRGEIPMDWPLIGLANP 84 Query: 125 GPAW-----REQRRFSVSTLRNLGLGKKSLEQW---VTEEAACLCAAFANH-SGRPFRPN 175 G + + RR TL L K +E+ + A +G P Sbjct: 85 GRSMLTVDGADHRRL--RTLVAQALTVKRVERLRAGIEALTNASLEKLAALPAGEPVDLK 142 Query: 176 GLLDK-AVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIP 234 NVI+ E + ++ + Sbjct: 143 AEFAYPLPMNVIS-----------------------ELMGVDAADHPRLKELFEKFFSTQ 179 Query: 235 ALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDEN 294 +V + +++ R P DLT A +A E DE Sbjct: 180 TPPEEVPQMMADLGALFTKIVDAKR-----TNPGDDLTSALIAASE-----NGDHLTDEE 229 Query: 295 LRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMP 354 + + + +AG TT + + + + HP+ +++V ++ IG Sbjct: 230 IVNTLQLIIAAGHETTISLIVNVVEALQTHPEQRKKV---LNGEIGW------------- 273 Query: 355 YTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVW-EKPF 413 VI E R+ + + DIEV +PKG LI + ++ +DE + Sbjct: 274 --DGVIEETLRWNTPTSHVLIRFATEDIEVGDKILPKGEGLIISFGALGRDEEQYGPTAG 331 Query: 414 RFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF---SFSVPT 470 F P + F G C G L+R+E + +L + F +VP Sbjct: 332 EFDATR---------TPNRHIAFGHGPHVCPGAALSRLEAGIALPALYERFPELDLAVPA 382 Query: 471 GQPR 474 R Sbjct: 383 SDLR 386 >5XW2-A nrPDB Length = 419 Score = 172 bits (435), Expect = 4e-43, Method: Composition-based stats. Identities = 71/367 (19%), Positives = 124/367 (33%), Gaps = 55/367 (14%) Query: 117 QGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNG 176 +G L P RE R+ + LE +T L A A Sbjct: 91 EGDLLQTDPPDHRELRKLVSHAFTPKVVA--ELEPRITALTQELLDAVA----------- 137 Query: 177 LLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVP--VLLHIP 234 D+ +++ +L + LL + G++ E+++++ + P Sbjct: 138 --DRDTFDLMTALA----YPLPVTVVAELLSIPSADRHLFEGWMTEIVHSLGDVSMEDAP 191 Query: 235 ALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDEN 294 ++ A + ++ E L EH +P DL + + D + Sbjct: 192 EDQERIFEAGMAPMRKMLEYLREH-AAECRRRPRGDLMGKLIEAEVDGR-----RLTDNH 245 Query: 295 LRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMP 354 + L AG +TT+ + +L + +P+ RV+ D++ +P Sbjct: 246 IVNFAKMLLIAGYLTTTMLIGNTVLCLDSYPEQAARVR---------------ADRSLIP 290 Query: 355 YTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFR 414 + E RF V T+RD+EV G R+ ++ + +D + +P Sbjct: 291 GL---LEESMRFLSPVA-ATYRATTRDVEVAGQRLSADQMVMVWFGAANRDARQFAEPEL 346 Query: 415 FHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPR 474 F P L F G CLG PLARME + LL F + Sbjct: 347 FDMTR---------GPNPHLGFGRGIHFCLGGPLARMEGRVALDHLLDRFPELYTDPERP 397 Query: 475 PSHHGVF 481 P+ F Sbjct: 398 PTFMPGF 404 >2ZBZ-A nrPDB Length = 412 Score = 171 bits (434), Expect = 5e-43, Method: Composition-based stats. Identities = 83/444 (18%), Positives = 136/444 (30%), Gaps = 73/444 (16%) Query: 53 NTPYCFDQLRRRFGDVFSLQLA-WTPVVVLNGLAAVREALVT-HGEDTADRPPVPITQIL 110 P + QLR G + + L V+ A R+ L P T Sbjct: 25 QLPDGYAQLRDTPGPLHRVTLYDGRQAWVVTKHEAARKLLGDPRLSSNRTDDNFPATSPA 84 Query: 111 GFGPRSQGVFL-ARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSG 169 R P +RR ++S + K + V E Sbjct: 85 FEAVRESPQAFIGLDPPEHGTRRRMTISEFTVKRI--KGMRPEVEEVVHGFLDEMLAAGP 142 Query: 170 RPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPV 229 + S VI L Y D F + + ++ + Sbjct: 143 TADLVSQFALPVPSMVICRL---LGVPYADHEFFQD-------------ASKRLVQSTD- 185 Query: 230 LLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESS 289 A L + LD L+T+ + +P L A +A+ Sbjct: 186 -------AQSALTARNDLAGYLDGLITQFQ-----TEPGAGLVGALVADQL-----ANGE 228 Query: 290 FNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGD 349 + E L L AG TT++ + ++ ++ HP+ ++ + V G Sbjct: 229 IDREELISTAMLLLIAGHETTASMTSLSVITLLDHPEQYAALRADRSLVPG--------- 279 Query: 350 QAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVW 409 + E+ R+ I + + + DIEV+G I G +I S +D V+ Sbjct: 280 ---------AVEELLRYLAIADIAGGRVATADIEVEGQLIRAGEGVIVVNSIANRDGTVY 330 Query: 410 EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQH---FSF 466 E P L F G CLG+ LAR+EL + +L+ Sbjct: 331 EDPDALDIHR---------SARHHLAFGFGVHQCLGQNLARLELEVILNALMDRVPTLRL 381 Query: 467 SVPTGQ----PRPSHHGVFAFLVS 486 +VP Q P + GV V+ Sbjct: 382 AVPVEQLVLRPGTTIQGVNELPVT 405 >4Z5P-A nrPDB Length = 400 Score = 171 bits (434), Expect = 6e-43, Method: Composition-based stats. Identities = 63/363 (17%), Positives = 114/363 (31%), Gaps = 67/363 (18%) Query: 115 RSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRP 174 R L+ P RR +G +++ W+ E A L G P Sbjct: 81 RRSDTILSLDPPEHTRLRRLLSKAFTARRMG--AMQSWLEELFAGLLDGVERT-GHPADI 137 Query: 175 -NGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHI 233 L VI RLL + E + +++ Sbjct: 138 VRDLAQPFTIAVIC----------------RLLGVPYEDRGRFQHWSEVIMSTTAYSK-- 179 Query: 234 PALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDE 293 + + + L +L++ R A P DL ++ + + ++ Sbjct: 180 ----EEAVSADASIRAYLADLVSARR-----AAPHDDLLGVLVSAR-----DDDDRLTED 225 Query: 294 NLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHM 353 L L AG T++ L + ++ H D ++++ + Sbjct: 226 ELITFGVTLLVAGHETSAHQLGNMVYALLTHEDQLSLLREQPE----------------- 268 Query: 354 PYTTAVIHEVQRFGDIVP-LGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKP 412 + E+ RF + +G + D+E+ G + G ++ + +D ++ P Sbjct: 269 -LLPRAVEELLRFVPLGNGVGNARIALEDVELSGGTVRAGEGVVAAAVNANRDPRAFDDP 327 Query: 413 FRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS---FSVP 469 R + L F G CLG LARMEL + LL+ F +VP Sbjct: 328 DRLDITR---------EKNPHLAFGHGAHYCLGAQLARMELRVAIGGLLERFPGLRLAVP 378 Query: 470 TGQ 472 Q Sbjct: 379 ADQ 381 >5LIV-A nrPDB Length = 450 Score = 171 bits (433), Expect = 6e-43, Method: Composition-based stats. Identities = 75/388 (19%), Positives = 118/388 (30%), Gaps = 57/388 (14%) Query: 90 ALVTHGEDTAD-RPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS 148 L+ T R + + G A G RR + + Sbjct: 92 ILLRKSHITTAYRDTATFSTRMFQAGILNGGLAAMQGDEHARMRR-VYNMFFLPRAVSQY 150 Query: 149 LEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208 E++V + + A + VI L Sbjct: 151 EERFVRPISEQVVDRLAGKPRVDL-LEDFAMELPRRVIG----------------ELFGF 193 Query: 209 AQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPP 268 E L E +R +L + V +H PA + R L + E++ Sbjct: 194 PAEKLHETDERVRAMLRGL-VRMHDPAAVAESQRAYGETLGLITEVVER---------ES 243 Query: 269 RDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQ 328 RD ++ L E+ + E R +V L G TTS +A + ++ HPD Sbjct: 244 RDTSDTLLGEILRTLKAEHMD-TIEASRQIVLSLILGGYETTSWLVANTIHALLAHPDTL 302 Query: 329 RRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFR 388 RV+Q+ A I E R+ GV M RD+ + Sbjct: 303 ARVRQDPS------------------LLPAAIEEGMRWCPSS-FGVLRMVERDVRLDDQA 343 Query: 389 IPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPL 448 + GT + + DE + P + + + F G C+G PL Sbjct: 344 LSAGTVVCLAGIAGNYDETAYPSPEVYDIDRKPLPAANV--------FGGGAHFCVGAPL 395 Query: 449 ARMELFLFFTSLLQHFSFSVPTGQPRPS 476 ARME + +LL F + RPS Sbjct: 396 ARMEARVGLQALLARFPGLRAVPEERPS 423 >1EHE-A nrPDB Length = 403 Score = 171 bits (432), Expect = 8e-43, Method: Composition-based stats. Identities = 75/447 (16%), Positives = 132/447 (29%), Gaps = 72/447 (16%) Query: 52 QNTPYCFDQLRRRFGDVFSLQL--AWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQI 109 P F +LR V ++L +V A R P Sbjct: 16 PEPPAEFAKLRAT-NPVSQVKLFDGSLAWLVTKHKDVCFVATSEKLSKVRTRQGFPELSA 74 Query: 110 LG-FGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFAN-- 166 G +++ F+ P QR T + K+L+ ++ L Sbjct: 75 SGKQAAKAKPTFVDMDPPEHMHQRSMVEPTFTPEAV--KNLQPYIQRTVDDLLEQMKQKG 132 Query: 167 HSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNA 226 + P V + I G ++D +L Q ++ Sbjct: 133 CANGPVDLVKEFALPVPSYIIYTLLG--VPFNDLEYL----TQQNAIRTNGS-------- 178 Query: 227 VPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNP 286 + A + + L L L+ + +P D+ E K Sbjct: 179 --------STAREASAANQELLDYLAILVEQR-----LVEPKDDIISKLCTEQVKP---- 221 Query: 287 ESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPE 346 + + + + L AG T +A G+ + HPD +++ Sbjct: 222 -GNIDKSDAVQIAFLLLVAGNATMVNMIALGVATLAQHPDQLAQLKANPS---------- 270 Query: 347 MGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDE 406 + E+ R+ L + D+ + + +I + S +DE Sbjct: 271 --------LAPQFVEELCRYHTASALAIKRTAKEDVMIGDKLVRANEGIIASNQSANRDE 322 Query: 407 AVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS- 465 V+E P F+ P+ L F G C+ E LA+ EL F++L Q F Sbjct: 323 EVFENPDEFNMNR-------KWPPQDPLGFGFGDHRCIAEHLAKAELTTVFSTLYQKFPD 375 Query: 466 --FSVPTGQ----PRPSHHGVFAFLVS 486 +VP G+ P G+ V Sbjct: 376 LKVAVPLGKINYTPLNRDVGIVDLPVI 402 >6F88-A nrPDB Length = 400 Score = 170 bits (430), Expect = 2e-42, Method: Composition-based stats. Identities = 75/388 (19%), Positives = 118/388 (30%), Gaps = 57/388 (14%) Query: 90 ALVTHGEDTAD-RPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS 148 L+ T R + + G A G RR + + Sbjct: 42 ILLRKSHITTAYRDTATFSTRMFQAGILNGGLAAMQGDEHARMRR-VYNMFFLPRAVSQY 100 Query: 149 LEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208 E++V + + A + VI L Sbjct: 101 EERFVRPISEQVVDRLAGKPRVDL-LEDFAMELPRRVIG----------------ELFGF 143 Query: 209 AQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPP 268 E L E +R +L + V +H PA + R L + E++ Sbjct: 144 PAEKLHETDERVRAMLRGL-VRMHDPAAVAESQRAYGETLGLITEVVER---------ES 193 Query: 269 RDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQ 328 RD ++ L E+ + E R +V L G TTS +A + ++ HPD Sbjct: 194 RDTSDTLLGEILRTLKAEHMD-TIEASRQIVLSLILGGYETTSWLVANTIHALLAHPDTL 252 Query: 329 RRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFR 388 RV+Q+ A I E R+ GV M RD+ + Sbjct: 253 ARVRQDPS------------------LLPAAIEEGMRWCP-SNFGVLRMVERDVRLDDQA 293 Query: 389 IPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPL 448 + GT + + DE + P + + + F G C+G PL Sbjct: 294 LSAGTVVCLAGIAGNYDETAYPSPEVYDIDRKPLPAANV--------FGGGAHFCVGAPL 345 Query: 449 ARMELFLFFTSLLQHFSFSVPTGQPRPS 476 ARME + +LL F + RPS Sbjct: 346 ARMEARVGLQALLARFPGLRAVPEERPS 373 >5Y1I-A nrPDB Length = 403 Score = 169 bits (429), Expect = 2e-42, Method: Composition-based stats. Identities = 75/428 (17%), Positives = 126/428 (29%), Gaps = 73/428 (17%) Query: 70 SLQLAWTPVVVLNGLAAVREALVTHGEDTAD-RPPVPITQI-LGFGPRSQGVFLARYGPA 127 + TP VV R L R P F +Q F + P Sbjct: 37 RIWDGSTPWVVTRHADQ-RALLSDPRVSHDGLRDGYPHISADFKFLSMAQPSFAGQDDPE 95 Query: 128 WREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDK-AVSNVI 186 RR TL +++ + + L +P L VI Sbjct: 96 HGRIRRMV--TLPFTARRIEAMRPAIQKITDELIDGMLAGP-KPVDLVEALALPVPVRVI 152 Query: 187 ASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKA 246 + Y+D FL+ + A G + A Sbjct: 153 CEM---LGVPYEDREFLQQNNNAMIYRDTAQG--------------------DAQKAAIA 189 Query: 247 FLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAG 306 L EL+ D+ ++E ++ + L AG Sbjct: 190 QAMYLKELV-----GTKLGDRGDDILSDLAVQVEA------GEITQDDAAGIGMMLLGAG 238 Query: 307 MVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRF 366 TT+ +A G L ++ +P+ V+ D + + E+ R+ Sbjct: 239 HETTANMIALGTLALLENPEQLAEVRDSDDPKV----------------IVNTVEELLRY 282 Query: 367 GDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEK-PFRFHPEHFLDAQG 425 I V + + DIE+ G I G ++ L++ D ++ + P R Sbjct: 283 LTIAQDTVRRIAAEDIEIGGVVIKAGEGIVFPLNAANWDPDLYPEAPDRLDIHR------ 336 Query: 426 HFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS-------FSVPTGQPRPSHH 478 L F G CLG LAR+EL + +++LL+ + H Sbjct: 337 --ANARRHLAFGYGVHQCLGATLARVELQIVYSTLLRRIPTLALAGTLDEIPFKHDQIAH 394 Query: 479 GVFAFLVS 486 GV+ V+ Sbjct: 395 GVYELPVT 402 >5LIE-A nrPDB Length = 414 Score = 169 bits (427), Expect = 4e-42, Method: Composition-based stats. Identities = 69/341 (20%), Positives = 108/341 (31%), Gaps = 57/341 (16%) Query: 125 GPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPN-GLLDKAVS 183 P RR S L + + +E + A L G PF + + Sbjct: 100 DPRHTRIRRLVSSGLTPRMIRR--VEDDLRRRARGLLDGV--EPGAPFDFVVEIAAELPM 155 Query: 184 NVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRF 243 +I L + L + + G + V Sbjct: 156 QMICIL-----LGVPETDRHWLFEAVEPGFDFRGSRRATM------------PRLNVEDA 198 Query: 244 QKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLF 303 T EL+ R A+P D+ P + +D L + LF Sbjct: 199 GSRLYTYALELIAGKR-----AEPADDMLSVVANATIDDPDAP--ALSDAELYLFFHLLF 251 Query: 304 SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEV 363 SAG TT ++A GLL + +PD + ++ + + I E+ Sbjct: 252 SAGAETTRNSIAGGLLALAENPDQLQTLRSDFE------------------LLPTAIEEI 293 Query: 364 QRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDA 423 R+ P SR + + G I G ++ S +D +V+++ F Sbjct: 294 VRWTSPSP-SKRRTASRAVSLGGQPIEAGQKVVVWEGSANRDPSVFDRADEFDITR---- 348 Query: 424 QGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464 KP L F G CLG LAR+EL + F LL F Sbjct: 349 -----KPNPHLGFGQGVHYCLGANLARLELRVLFEELLSRF 384 >4JBT-A nrPDB Length = 410 Score = 168 bits (425), Expect = 6e-42, Method: Composition-based stats. Identities = 69/416 (16%), Positives = 126/416 (30%), Gaps = 72/416 (17%) Query: 66 GDVFSLQLAWTPVVVLNGLAAVREALVT--HGEDTADRPPVPITQI----LGFGPRSQGV 119 G + + L P + + G R+ L +D + G Sbjct: 30 GPLTRIDLLGVPALAVTGHTLARQLLTDTRLVKDINAWSLWQSGTVTRQWPLIGMIDVDR 89 Query: 120 F-LARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHS--GRPFRPNG 176 GP R R + L L +L+ + A L G Sbjct: 90 SMFTVDGPEHRRLRIKTTQALTRRRL--DALKPTIERYVAELLDDLERAGADGAVVDLKS 147 Query: 177 LLDK-AVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPA 235 + VI++ L+ + E ++ + + + + Sbjct: 148 VFAYPLPMRVISA----------------LMGVPSEDQEQLLTWYKAFFSIL-------T 184 Query: 236 LAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENL 295 + LR E++ A+P DLT A + + E+ +E + Sbjct: 185 PQDERLRVIDEMHGYFTEMVRRK-----TAEPGDDLTSALI-----YATDGETPLTEEEV 234 Query: 296 RIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPY 355 + L +AG TT + + + ++ HP+ R V+ D IG Sbjct: 235 IGNLQALVAAGHETTVSLILTAVRALLSHPEQLRLVR---DGEIGW-------------- 277 Query: 356 TTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVW-EKPFR 414 I E R+ V + + DI++ IP+G ++ + ++ +D V Sbjct: 278 -ETAIEETLRWDGPVIHLLMRFATEDIDLGDAVIPRGEGVVMSYRAIGRDITVHGADADD 336 Query: 415 FHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPT 470 F A+ + F G C G LAR+E + +L F P Sbjct: 337 FDITRATAAR--------HISFGHGPHICPGAALARLEAAIALPALFTRFPHLHPA 384 >1CPT-A nrPDB Length = 428 Score = 167 bits (424), Expect = 8e-42, Method: Composition-based stats. Identities = 68/371 (18%), Positives = 123/371 (33%), Gaps = 51/371 (13%) Query: 125 GPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSN 184 P R +++ + + + LE+ + A + G + Sbjct: 107 PPTHTAYRGLTLNWFQPASI--RKLEENIRRIAQASVQRLLDFDGECDFMTDCALYYPLH 164 Query: 185 VIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQ 244 V+ +T E D+P L+L + + + + RF Sbjct: 165 VV--MTALGVPEDDEPLMLKLTQDFFGVHEPDEQAVAAPRQSAD---------EAARRFH 213 Query: 245 KAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFS 304 + T D + T D P+D + LA + + +D+ + + + Sbjct: 214 ETIATFYDYF---NGFTVDRRSCPKDDVMSLLANSKL----DGNYIDDKYINAYYVAIAT 266 Query: 305 AGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQ 364 AG TTS++ ++ + +P+ + D A +P + E Sbjct: 267 AGHDTTSSSSGGAIIGLSRNPEQLALAK---------------SDPALIPRL---VDEAV 308 Query: 365 RFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQ 424 R+ V D EV+G I +G ++ + S +DE V+ P F F Sbjct: 309 RWTAPVK-SFMRTALADTEVRGQNIKRGDRIMLSYPSANRDEEVFSNPDEFDITRF---- 363 Query: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFL 484 P L F G CLG+ LA++E+ +FF LL +G PR F+ Sbjct: 364 -----PNRHLGFGWGAHMCLGQHLAKLEMKIFFEELLPKLKSVELSGPPRLVATN---FV 415 Query: 485 VSPSPYELCAV 495 P + Sbjct: 416 GGPKNVPIRFT 426 >5EX6-C nrPDB Length = 434 Score = 167 bits (423), Expect = 1e-41, Method: Composition-based stats. Identities = 65/428 (15%), Positives = 121/428 (28%), Gaps = 79/428 (18%) Query: 66 GDVFSLQLAW----TPVVVLNGLAAVREALVTHGEDTADRPPVPITQIL-----GFGPRS 116 G++ ++L + G VR+ L H + R + Sbjct: 62 GELTRVRLGSGADAEHTWLATGHDVVRQVLGDHTR-FSTRRRFDRNDEIGGKGVFRPREL 120 Query: 117 QGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNG 176 G + P RR + + + + ++ + G P Sbjct: 121 VGNLMDYDPPEHTRLRRLLAPGFTHRKIRR--MAPYIEQIVTERLDEMERE-GSPADLIE 177 Query: 177 LL-DKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPA 235 L D+ V+ L DD L Sbjct: 178 LFADEVPGPVLCEL---LGVPRDDRAMFLQLCHRHLDASLSG------------------ 216 Query: 236 LAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENL 295 + +AF L ++ R D + + + G+ + DE L Sbjct: 217 --RRRAAAGEAFSRYLVTMVARERK---------DPGDGLIGMVVAEHGD---TVTDEEL 262 Query: 296 RIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPY 355 R V + AG S + G+L ++ +P+ ++ ++ P Sbjct: 263 RGVCVQMMLAGDDNISGMIGLGVLALLRNPEQIAALRGDV------------------PA 304 Query: 356 TTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRF 415 + E+ R+ + D V I G T++ +L + +D A+ R Sbjct: 305 AERAVDELIRYLTVPYAPTPRTAIEDSTVGDQVIKAGETVLCSLPTANRDPALLPDADRL 364 Query: 416 HPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS---FSVPTGQ 472 + + F G CLG LAR+EL + +T+L + F + P G Sbjct: 365 DVTR---------EAVPHVAFGHGVHHCLGAALARLELRIAYTALWRRFPDLRLADPDGA 415 Query: 473 PRPSHHGV 480 Sbjct: 416 TEFRLSTP 423 >3ABB-A nrPDB Length = 408 Score = 166 bits (420), Expect = 2e-41, Method: Composition-based stats. Identities = 79/445 (17%), Positives = 135/445 (30%), Gaps = 78/445 (17%) Query: 53 NTPYCFDQLRRRFGDVFSLQLA-WTPVVVLNGLAAVREALVT-HGEDTADRPPVPITQIL 110 P +++ R + + L P ++ G A R LV P P+ Sbjct: 25 QPPKAYEERRGE-SPLTQVTLFDGRPAWLITGHAEGRALLVDPRLSSDWGHPDFPVVVRR 83 Query: 111 GFGPRSQGVFLARYG---PAWREQRRFSVSTLRNLGLGK-KSLEQWVTEEAACLCAAFAN 166 G+ G P QRR + + G+ + ++ + L Sbjct: 84 TEDR--GGLAFPLIGVDDPVHARQRRMLIP---SFGVKRMNAIRPRLQSLVDRLLDDMLA 138 Query: 167 HSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNA 226 G V +V ++ Y D F G + Sbjct: 139 -KGPGADLVSAFALPVPSV--AICELLGVPYGDHDFFEECSRNFVGAATSAEADAAF--- 192 Query: 227 VPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNP 286 T L L+ + A+P L + +A + Sbjct: 193 ------------------GELYTYLHGLVGRKQ-----AEPEDGLLDELIARQLE----- 224 Query: 287 ESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPE 346 E + + + ++ L AG TT +A G L +I HP+ + ++ V G Sbjct: 225 EGDLDHDEVVMIALVLLVAGHETTVNAIALGALTLIQHPEQIDVLLRDPGAVSG------ 278 Query: 347 MGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDE 406 V+ E+ RF + + M DIEV G I G ++ +++ + +D Sbjct: 279 ------------VVEELLRFTSVSD-HIVRMAKEDIEVGGATIKAGDAVLVSITLMNRDA 325 Query: 407 AVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQH--- 463 +E P F + F G CLG+ LAR EL + L Sbjct: 326 KAYENPDIFDARRNA---------RHHVGFGHGIHQCLGQNLARAELEIALGGLFARIPG 376 Query: 464 FSFSVPTGQ-PRPSHHGVFAFLVSP 487 +VP + P + H + P Sbjct: 377 LRLAVPLDEVPIKAGHDAQGPIELP 401 >3TYW-A nrPDB Length = 417 Score = 165 bits (418), Expect = 4e-41, Method: Composition-based stats. Identities = 73/398 (18%), Positives = 129/398 (32%), Gaps = 70/398 (17%) Query: 80 VLNGLAAVREALVT-HGEDTADRPPVPITQILGF--GPRSQGVFLARYGPAWREQRRFSV 136 V+ VRE L RP P G R + R +R Sbjct: 57 VVTRYDDVRELLSDPRVSADIRRPGFPALGEGEQEAGARFRPFIRTDAPEHTRYRRMLLP 116 Query: 137 S-TLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVS-NVIASLTCGRR 194 + T+R + + +++ V E + AA G P AVS +VI L R Sbjct: 117 AFTVRRVRAMRPAVQARVDEILDGMLAA-----GGPVDLVSAYANAVSTSVICELLGIPR 171 Query: 195 FEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDEL 254 + L+ ++ + + A +V L L Sbjct: 172 HD---------LEFFRDVTRISGSR--------------NSTAEQVSEALGGLFGLLGGL 208 Query: 255 LTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTL 314 + E R +P DL + + + E L + +AG TT++ + Sbjct: 209 VAERRE-----EPRDDLISKLVTDHLVP-----GNVTTEQLLSTLGITINAGRETTTSMI 258 Query: 315 AWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGV 374 A LL++ P++ ++++ D A + E+ R + Sbjct: 259 ALSTLLLLDRPELPAELRKDPD------------------LMPAAVDELLRVLSVADSIP 300 Query: 375 THMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFL 434 + + DIE+ G +P +I L+ D ++ P R + Sbjct: 301 LRVAAEDIELSGRTVPADDGVIALLAGANHDPEQFDDPERVDFHR---------TDNHHV 351 Query: 435 PFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQ 472 F G C+G+ LAR+EL + +LL+ G+ Sbjct: 352 AFGYGVHQCVGQHLARLELEVALETLLRRVPTLRLAGE 389 >3P3Z-A nrPDB Length = 416 Score = 163 bits (413), Expect = 1e-40, Method: Composition-based stats. Identities = 63/343 (18%), Positives = 110/343 (32%), Gaps = 51/343 (14%) Query: 143 GLGKKSLEQWVTEEAACLCAAFANHSGRPFRPN------GLLDKAVSNVIASLT-----C 191 G + + ++ + PF P + V +I L Sbjct: 90 GPVRDFMVDFLQSLDGADHRRLRGLATHPFTPRRITAVQPFVRSTVEQLIDKLPQGDFDF 149 Query: 192 GRRFEYDDPRFL--RLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLT 249 + F + P + +LL E E + + +++ ++ Sbjct: 150 VQHFPHPLPALVMCQLLGFPLEDYDTVGRLSIETNLGLA----LSNDQDILVKVEQGLGR 205 Query: 250 QLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVT 309 D L+ + +P DLT + + +D LR +VA + AG T Sbjct: 206 MFDYLVAA--IEKRKVEPGDDLTSDIVRAFH------DGVLDDYELRTLVATVLVAGYET 257 Query: 310 TSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDI 369 T+ LA + HPD ++++ + + EV R+ Sbjct: 258 TNHQLALAMYDFAQHPDQWMKIKENPE------------------LAPQAVEEVLRWSPT 299 Query: 370 VPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVK 429 +P+ T + + D EV G RIP GT + +D V+ RF + Sbjct: 300 LPVTATRVAAEDFEVNGVRIPTGTPVFMCAHVAHRDPRVFADADRFDIT--------VKR 351 Query: 430 PEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQ 472 + F G CLG LAR+EL +L G+ Sbjct: 352 EAPSIAFGGGPHFCLGTALARLELTEAVAALATRLDPPQIAGE 394 >3WVS-A nrPDB Length = 401 Score = 163 bits (412), Expect = 2e-40, Method: Composition-based stats. Identities = 60/354 (16%), Positives = 101/354 (28%), Gaps = 64/354 (18%) Query: 121 LARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRP-NGLLD 179 P RR + + L V + A L G P Sbjct: 91 FNMDAPDHTRLRRLISKAFTIRRV--EELRPKVHDLAHRLIDDMLA-KGEPADLVADYAL 147 Query: 180 KAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGK 239 + VI L G FE D +F R D + Sbjct: 148 PIPTTVICEL-LGVPFE-DREKFGRWTDAILSTSTLN--------------------PEE 185 Query: 240 VLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVV 299 + + + ++ R AQP DL + + + ++ L Sbjct: 186 GRVKRMELVGYIGGIIAARR-----AQPADDLISGMIEAR-----DVQDKLTEQELLDHC 235 Query: 300 ADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAV 359 L AG TT++ + + ++ P +R+ + + + Sbjct: 236 IGLLIAGHETTASQIPSFVYALLDQPQHWKRLLDDPE------------------LIPSA 277 Query: 360 IHEVQRFGDI-VPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418 + E+ RF + DIEV G + G ++ L + +D +E P + Sbjct: 278 VEELFRFVPLGSGSAAPRYAREDIEVGGTLVRAGEPVLVALGAANRDGLRFEDPEEIKLD 337 Query: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQ 472 + F G CLG PLAR+EL +LL+ G Sbjct: 338 R---------PSNHHIGFGHGIHHCLGAPLARLELQEALRALLERLPTLKVAGD 382 >4WPZ-A nrPDB Length = 397 Score = 162 bits (410), Expect = 3e-40, Method: Composition-based stats. Identities = 65/405 (16%), Positives = 127/405 (31%), Gaps = 75/405 (18%) Query: 80 VLNGLAAVREALVTHGEDTADR---PPVPITQILGFGPRSQGVFLARYGPAWREQRRFSV 136 ++ A VR+ LV + + G + P R+ Sbjct: 41 MVTKHADVRKVLVD--SRFSSKVMATAAAAMSETETGKLMNESLVGMDAPEHTRLRKLVT 98 Query: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDK-AVSNVIASLTCGRRF 195 ++L +TE L RP VI L Sbjct: 99 KAFT--ARRVETLRPRITELVGQLLDELETLP-RPVDLVKNFSVPLPVRVICEL---LGV 152 Query: 196 EYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELL 255 D D G ++V+ + + + EL+ Sbjct: 153 PAGDQ------DTFHAWSNALLGDWQQVV--------------EKEAATVSLVNYFGELI 192 Query: 256 TEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLA 315 R P DL +A + +S+ + + + + SAG TT+ ++ Sbjct: 193 AVKRE-----NPADDLISELIAIS-----DGDSTLTEREIIALSIGILSAGHETTANQIS 242 Query: 316 WGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLG-- 373 L+ ++ +P+ +++ + + + E+ RF + G Sbjct: 243 MFLVTLLHNPEELDKLRDNREAI------------------PKAVDELLRFVPLTTTGGI 284 Query: 374 VTHMTSRDIEV-QGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEA 432 + +T+ ++E+ G +P G ++ +++ +D V+E R + + Sbjct: 285 IPRLTTAEVELSGGQVLPAGAVVLPAVATANRDPEVFEDGERLNVTR---------ENNP 335 Query: 433 FLPFSAGRRACLGEPLARMELFLFFTSLLQHFS---FSVPTGQPR 474 L F AG CLG LAR+EL ++L +VP + R Sbjct: 336 HLAFGAGIHHCLGAQLARIELQEALGAILDRMPQVRLAVPESELR 380 >1GWI-A nrPDB Length = 411 Score = 162 bits (410), Expect = 3e-40, Method: Composition-based stats. Identities = 74/422 (17%), Positives = 126/422 (29%), Gaps = 75/422 (17%) Query: 66 GDVFSLQL-AWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARY 124 G + +++L PV + A + AL+T D + + LA Sbjct: 30 GPLAAVELPGGVPVWAVTHHAEAK-ALLTDPRLVKDINVWGAWRRGEIPADWPLIGLANP 88 Query: 125 GPAW-----REQRRFSVSTLRNLGLGKKSLEQ---WVTEEAACLCAAFANHSGRPFRPNG 176 G + E RR TL L + +E +TE L G Sbjct: 89 GRSMLTVDGAEHRRL--RTLVAQALTVRRVEHMRGRITELTDRLLDELPAD-GGVVDLKA 145 Query: 177 LLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPAL 236 F Y P + + + + E L + Sbjct: 146 A-----------------FAYPLP-----MYVVADLMGIEEARLPRLKVLFEKFFSTQTP 183 Query: 237 AGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLR 296 +V+ + + + + R A P DLT A + E D + Sbjct: 184 PEEVVATLTELASIMTDTVAAKR-----AAPGDDLTSALIQASE-----NGDHLTDAEIV 233 Query: 297 IVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYT 356 + + +AG TT + + ++ + HP+ + V + Sbjct: 234 STLQLMVAAGHETTISLIVNAVVNLSTHPEQRALVLSGEAEW------------------ 275 Query: 357 TAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVW-EKPFRF 415 +AV+ E RF + + D+ V IP G LI + ++ +DE RF Sbjct: 276 SAVVEETLRFSTPTSHVLIRFAAEDVPVGDRVIPAGDALIVSYGALGRDERAHGPTADRF 335 Query: 416 HPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF---SFSVPTGQ 472 + F G C G L+RME + +L F +VP + Sbjct: 336 DLTR--------TSGNRHISFGHGPHVCPGAALSRMEAGVALPALYARFPHLDLAVPAAE 387 Query: 473 PR 474 R Sbjct: 388 LR 389 >1ODO-A nrPDB Length = 408 Score = 162 bits (409), Expect = 4e-40, Method: Composition-based stats. Identities = 69/412 (16%), Positives = 114/412 (27%), Gaps = 69/412 (16%) Query: 81 LNGLAAVREALVTHGEDTADRPPVPIT-----QILGFGPRSQGVFLARYGPAWREQRRFS 135 ++ +++ L + R P + YGP R+ RR Sbjct: 43 VSDPVLLKQLLTSSDVSKDARAHWPAFGEVVGTWPLALWVAVENMFTAYGPNHRKLRRLV 102 Query: 136 VSTLRNLGLGKKSLEQWVTEEAACLCAAFANH-SGRPFRPNGLLDK-AVSNVIASLTCGR 193 ++ V L A +G P L VI Sbjct: 103 APAFS--ARRVDAMRPAVEAMVTGLVDRLAELPAGEPVDLRQELAYPLPIAVIG------ 154 Query: 194 RFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDE 253 L+ + Q+ + V + + LD+ Sbjct: 155 ----------HLMGVPQDRRDGFRALVDGVFDTT-------LDQAEAQANTARLYEVLDQ 197 Query: 254 LLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTT 313 L+ R T P D+T +A + + E LR + + SAG TT Sbjct: 198 LIAAKRAT-----PGDDMTSLLIAA--RDDEGDGDRLSPEELRDTLLLMISAGYETTVNV 250 Query: 314 LAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLG 373 + + ++ PD V++ D V+ E R V Sbjct: 251 IDQAVHTLLTRPDQLALVRK---------GEVTWAD---------VVEETLRHEPAVKHL 292 Query: 374 VTHMTSRDIEV-QGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEA 432 DI + G I +G ++ + ++ + E F + Sbjct: 293 PLRYAVTDIALPDGRTIARGEPILASYAAANRHPDWHEDADTFDATRTVKE--------- 343 Query: 433 FLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVP--TGQPRPSHHGVFA 482 L F G CLG PLARME+ L SL F + P + + Sbjct: 344 HLAFGHGVHFCLGAPLARMEVTLALESLFGRFPDLRLADPAEELPPVPSLIS 395 >4YT3-A nrPDB Length = 410 Score = 162 bits (409), Expect = 4e-40, Method: Composition-based stats. Identities = 64/395 (16%), Positives = 128/395 (32%), Gaps = 63/395 (15%) Query: 84 LAAVREAL--VTHGEDTADRPPVPITQILGFGPRSQGVFLARYGP-AWREQRRFSVSTLR 140 V+ L H R + + G + + + P R++R + Sbjct: 49 YEDVKRVLSDYKHFSSVRKRTTISVGTDSEEGSVPEKIQITESDPPDHRKRRSLLAAAFT 108 Query: 141 NLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDP 200 L ++ E + E A L G L + +I Sbjct: 109 PRSL--QNWEPRIQEIADELIGQM--DGGTEIDIVASL-ASPLPIIV------------- 150 Query: 201 RFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRM 260 L+ + + ++ + L +V + ++ + + L + Sbjct: 151 -MADLMGVPSKDRLLFKKWVDTLF-----LPFDREKQEEVDKLKQVAAKEYYQYLYPI-V 203 Query: 261 TWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLL 320 P D+ L + F D+ + + AG+ TTS LA Sbjct: 204 VQKRLNPADDIISDLLKSEVDGE-----MFTDDEVVRTTMLILGAGVETTSHLLANSFYS 258 Query: 321 MI-LHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTS 379 ++ +V + + + +D V + E+ RF + + Sbjct: 259 LLYDDKEVYQELHENLDLV------------------PQAVEEMLRFR-FNLIKLDRTVK 299 Query: 380 RDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAG 439 D ++ G + +G +++ +S+ DE ++E PF + + + L F G Sbjct: 300 EDNDLLGVELKEGDSVVVWMSAANMDEEMFEDPFTLNIHRPNNKK--------HLTFGNG 351 Query: 440 RRACLGEPLARMELFLFFTSLLQHFSF--SVPTGQ 472 CLG PLAR+E + T+ L+ F +VP+ Q Sbjct: 352 PHFCLGAPLARLEAKIALTAFLKKFKHIEAVPSFQ 386 >6B11-A nrPDB Length = 440 Score = 162 bits (409), Expect = 4e-40, Method: Composition-based stats. Identities = 67/351 (19%), Positives = 110/351 (31%), Gaps = 67/351 (19%) Query: 142 LGLGK-KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDP 200 GL + + L V + L + VI Sbjct: 149 FGLRRVRELRPSVEQIVTGLLDDLTARGDEADLLADFALPMATQVIC------------- 195 Query: 201 RFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRM 260 RLLD+ E + PA + L LD L++ Sbjct: 196 ---RLLDIPYEDRDYFQERTEQATR--------PAAGEEALEALLELRDYLDRLIS---- 240 Query: 261 TWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLL 320 + R+ + L M + ++ L +AG TT++ + +L+ Sbjct: 241 ----GKTGRESGDGMLGSMVA--QARGGGLSHADVLDNAVLLLAAGHETTASMVTMSVLV 294 Query: 321 MILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSR 380 ++ HP R + + + E+ R+ I G+ + Sbjct: 295 LLQHPTAWREL------------------TVNPGLLPGAVDELLRYLSIAD-GLRRSATA 335 Query: 381 DIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGR 440 DIE+ G I G L+ L++ +DEAV+ +P F + F G Sbjct: 336 DIEIDGHTIRAGDGLVFLLAAANRDEAVFSEPEAFDIHR---------SARRHVAFGYGP 386 Query: 441 RACLGEPLARMELFLFFTSLLQHFSFSVPT----GQPRPSHHGVFAFLVSP 487 CLG+ LARMEL + ++L+ PT G S VF P Sbjct: 387 HQCLGQNLARMELEVALGAVLERLPALRPTTDVAGLRLKSDSAVFGVYELP 437 >5FOI-A nrPDB Length = 408 Score = 161 bits (407), Expect = 7e-40, Method: Composition-based stats. Identities = 74/405 (18%), Positives = 125/405 (30%), Gaps = 76/405 (18%) Query: 75 WTPVVVLNGLAAVREALVTH--GEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQR 132 +P +++ VR LV D +P + G G RS + P R Sbjct: 55 GSPTWLVSRYEHVRALLVDPRVTVDPTRQPRLSEADGDGDGFRSMLML---DPPEHTRLR 111 Query: 133 RFSVSTL--RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRP-NGLLDKAVSNVIASL 189 R +S R + + +E+ V L A P L + VI L Sbjct: 112 RMFISAFSVRQVETMRPEIEKIVDGILDRLLA-----LEPPVDILTHLALPMSTQVICHL 166 Query: 190 TCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLT 249 Y+D F QE + S + ++P L+ + Sbjct: 167 ---LGVPYEDREF------FQERSELASRPNDD--RSMPALI--------------ELVE 201 Query: 250 QLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVT 309 LD L+ D +TE L + + L L +AG T Sbjct: 202 YLDGLVRTKTAHPDTGLLGTAVTERLL----------KGEITHQELVNNAVLLLAAGHET 251 Query: 310 TSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDI 369 ++ + +L ++ HP+ ++++ + + E+ R+ I Sbjct: 252 SANQVTLSVLTLLRHPETAAELREQPE------------------LMPNAVDELLRYHSI 293 Query: 370 VPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVK 429 G+ + DI + I G LI LSS D + F Sbjct: 294 AD-GLRRAATADIVLGDHTIRAGDGLIILLSSANHDGNTFGAEATFDIHR---------P 343 Query: 430 PEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPR 474 + F G CLG+ LAR+E+ + L + +P Sbjct: 344 ARHHVAFGYGPHQCLGQNLARLEMEVTLGKLFRRVPALRLAQEPD 388 >5XNT-A nrPDB Length = 411 Score = 160 bits (405), Expect = 1e-39, Method: Composition-based stats. Identities = 64/374 (17%), Positives = 123/374 (32%), Gaps = 63/374 (16%) Query: 125 GPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSN 184 P R++R + L ++ E + E A L + L + Sbjct: 93 PPEHRKRRSLLAAAFTPRSL--QNWEPRIQEIADELIEEMDEET--EIDIVQSLASPLPI 148 Query: 185 VIASLTCGRRFEYDDPR-FLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRF 243 ++ S G D F + +D+ +E L V Sbjct: 149 IVMSDLMG--VPSKDRLLFKKWVDILFLPFDKEKQEEVNELKQV---------------A 191 Query: 244 QKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLF 303 K + L ++ + R+ P D+ L + F D+ + + Sbjct: 192 AKEYYQYLYPIVVQKRL-----NPADDIISDLLKAEVDGE-----MFTDDEVVRTTMLIL 241 Query: 304 SAGMVTTSTTLAWGLLLMI-LHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHE 362 AG+ TTS LA ++ +V + + + +D V + E Sbjct: 242 GAGVETTSHLLANSFYSLLYDDKEVYQELHENLDLV------------------PQAVEE 283 Query: 363 VQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLD 422 + R+ + + D ++ G + +G ++ +S+ DE ++E F + + Sbjct: 284 MLRYR-FNLIKLDRTVKEDNDLLGVELKEGENVVVWMSAANLDEEMFEDAFTLNIHRPNN 342 Query: 423 AQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSF--SVPTGQ-PRPSHHG 479 + L F G CLG PLAR+E + T+ L+ F +VP+ Q Sbjct: 343 KK--------HLTFGNGPHFCLGAPLARLEAKIALTTFLKKFKHIEAVPSFQLEDNLTDS 394 Query: 480 VFAFLVSPSPYELC 493 ++ P + C Sbjct: 395 ATGQTLTSLPLKAC 408 >4XE3-A nrPDB Length = 407 Score = 159 bits (403), Expect = 2e-39, Method: Composition-based stats. Identities = 75/436 (17%), Positives = 134/436 (30%), Gaps = 76/436 (17%) Query: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQL--AWTPVVVLNGLAAVREAL 91 P P LP + L +D Y + V ++L ++ ++ R L Sbjct: 15 PAYPFSLP---HALDLD---PHYAELRRDE---PVSRVRLPYGEGTAWLVTRMSDARIVL 65 Query: 92 VTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151 TA P T + P LA+ P RR + + Sbjct: 66 GDSRFSTAA-ATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFT--ARRVEEMRP 122 Query: 152 WVTEEAACLCAAFANHSGRPFRP-NGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQ 210 V L H G P L VI LL + Sbjct: 123 RVRSLVDSLLDDMVAH-GSPADLVEFLAVPFPVAVIC----------------ELLGVPL 165 Query: 211 EGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRD 270 E F +L++ A ++ R Q+ F+ +D L+ + R P D Sbjct: 166 EDRDLFRTFSDAMLSST------RLTAAEIQRVQQDFMVYMDGLVAQRRDA-----PTED 214 Query: 271 LTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRR 330 L A + + + + L AG T+ + + L++ Sbjct: 215 LLGAL-----ALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYES 269 Query: 331 VQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVT-HMTSRDIEVQGFRI 389 + + D A +P A + E+ R+ +V G + + D+E+ + Sbjct: 270 L---------------VADPALVP---AAVEEMLRYTPLVSAGSFVRVATEDVELSTVTV 311 Query: 390 PKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLA 449 G + + +S +DE V++ + + F G C+G L Sbjct: 312 RAGEPCVVHFASANRDEEVFDHADELDFHR---------ERNPHIAFGHGAHHCIGAQLG 362 Query: 450 RMELFLFFTSLLQHFS 465 R+EL ++L++ F Sbjct: 363 RLELQEALSALVRRFP 378 >5Z9I-A nrPDB Length = 398 Score = 159 bits (402), Expect = 2e-39, Method: Composition-based stats. Identities = 57/232 (24%), Positives = 87/232 (37%), Gaps = 37/232 (15%) Query: 257 EHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAW 316 R +P DL + + ND + + L G +TT+ +A Sbjct: 194 HERAAESRKRPREDLISQLVHAEVDGQ-----KLNDSQISNIANRLLVNGHLTTAMLIAN 248 Query: 317 GLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTH 376 +L + D RV+ D++ +P A++ E R+ + GV Sbjct: 249 TMLCLDAFSDQDARVR---------------ADRSLVP---ALLEESMRYMSPI-CGVGR 289 Query: 377 MTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPF 436 T+ ++EV G IPK L+ + +DE +EKP F P A L F Sbjct: 290 ATNSEVEVAGTVIPKDQLLLVWTGAANRDERQFEKPDVFDAGR---------SPNAHLGF 340 Query: 437 SAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPS 488 G CLG LARME LL +PT + P++ F +V S Sbjct: 341 GRGIHFCLGRQLARMESKAAVEILLDR----LPTLRADPANPPTFLQVVDAS 388 >6FSH-A nrPDB Length = 398 Score = 159 bits (402), Expect = 3e-39, Method: Composition-based stats. Identities = 70/390 (17%), Positives = 119/390 (30%), Gaps = 74/390 (18%) Query: 83 GLAAVREALVTHGEDTADRPPVPITQILG----FGPRSQGVFLARYGPAWREQRRFSVST 138 G A VR+ L H + + R +G F PR L Y P E R Sbjct: 47 GHAVVRQVLGDH-QQFSTRRRWDPRDEIGGKGIFRPRELVGNLMDYDP--PEHTRLRH-- 101 Query: 139 LRNLGLGKKSLEQWVTEEAACLCAAF--ANHSGRPFRPNGLL-DKAVSNVIASLTCGRRF 195 L G ++ + + + +G P L D+ V+ L R Sbjct: 102 LLTPGFTQRRMRRLAPRIEEIVTDRLDAMEQAGPPADLIELFADEVPGAVLCELIGVPR- 160 Query: 196 EYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELL 255 D F++L + + F L ++ Sbjct: 161 -DDRDMFMKLCHGHLDAS---------------------LSQKRRAALGDKFSRYLLAMI 198 Query: 256 TEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLA 315 R D + F+ + G+ + DE LR V L AG S + Sbjct: 199 ARERK---------DPGDGFIGSIVAEHGD---TITDEELRGVCVQLMLAGDDNVSGMIG 246 Query: 316 WGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVT 375 G+L ++ HP+ ++ + + E+ R+ + Sbjct: 247 LGVLALLRHPEQIAALRGDDQS------------------ADRAVDELIRYLTVPYAPTP 288 Query: 376 HMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLP 435 D+ V I +G T++ +L +D A+ R P + Sbjct: 289 RTAVEDVMVADQVIKEGETVLCSLPMANRDRALLPDADRLDVTR---------TPVPHVA 339 Query: 436 FSAGRRACLGEPLARMELFLFFTSLLQHFS 465 F G CLG L R++L + +T+L + F Sbjct: 340 FGHGIHHCLGAALTRLQLRIAYTALWRRFP 369 >6M7L-A nrPDB Length = 404 Score = 159 bits (401), Expect = 4e-39, Method: Composition-based stats. Identities = 82/413 (19%), Positives = 132/413 (31%), Gaps = 86/413 (20%) Query: 83 GLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNL 142 G VRE L E R G L P RR Sbjct: 67 GYDVVREVL--GSEKFDKRVIGTHFN--HQEMALPGNLLQLDPPEHTRLRRMVAPAYSVR 122 Query: 143 GLGKKSLEQWVTEEAACLCAAFANHSGRPFR-PNGLLDKAVSNVIASLTCGRRFEYDDPR 201 + ++LE V A+ G P + + V Sbjct: 123 RM--QALEPRVQAIVDDHLDTMAST-GPPVEFLREVAGPMAARVAC-------------E 166 Query: 202 FLRL-LDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRM 260 FL + LD E ++ + + + A+L + EL R Sbjct: 167 FLGIPLDDRGELIRLTAHR---------------GGKRRRVLNGHAYLAYMRELAARLR- 210 Query: 261 TWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLL 320 RD + L + + G + +DE L + A + ++ + T + LA G LL Sbjct: 211 --------RDPGDGMLGMVARDHG---ADISDEELAGLCAVVMNSSVEQTESCLAAGTLL 259 Query: 321 MILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSR 380 ++ HP+ +++ + + E+ R+ + + Sbjct: 260 LLEHPEQFALLRERPE------------------LGEQAVEEIVRYLSVFEGLDPRTATE 301 Query: 381 DIEVQGFRIPKGTTLITNLSSVLK-DEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAG 439 D+E+ G I KG + +L + + D A+ F K + F G Sbjct: 302 DVEIGGQVIKKGEAVFCSLLAANRADPAL----DGFDITR---------KESRHVAFGHG 348 Query: 440 RRACLGEPLARMELFLFFTSLLQHFSF---SVPTGQP--RPSHHGVFAFLVSP 487 CLG PLARMEL + FT+L+ F +VP + RP VF L P Sbjct: 349 IHHCLGAPLARMELRIAFTTLVSRFPSLRTAVPAEEIRFRPPSSNVFTLLELP 401 >1UED-A nrPDB Length = 406 Score = 158 bits (400), Expect = 4e-39, Method: Composition-based stats. Identities = 67/407 (16%), Positives = 122/407 (29%), Gaps = 69/407 (16%) Query: 70 SLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQ-GVFLARYGPAW 128 S QL V +G VR L H E RP ++ G P Sbjct: 47 STQLGRDFVWQAHGYEVVRRILGDH-EHFTTRPQFTQSKSGAHVEAQFVGQISTYDPPEH 105 Query: 129 REQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIAS 188 R+ + + +E + G GL V Sbjct: 106 TRLRKMLTPEFTVRRIRR--MEPAIQSLIDDRLDLLEAE-GPSADLQGLFADPVGA---- 158 Query: 189 LTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFL 248 L +L ++ F+R + + + AF Sbjct: 159 --------------HALCELLGIPRDDQREFVRRIRRNADLSRGL----KARAADSAAFN 200 Query: 249 TQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMV 308 LD LL R D + L + + G+ DE L+ + L G+ Sbjct: 201 RYLDNLLARQRA---------DPDDGLLGMIVRDHGDN---VTDEELKGLCTALILGGVE 248 Query: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGD 368 T + + +G+L ++ +P + + + V++E+ R+ Sbjct: 249 TVAGMIGFGVLALLDNPGQIELLFESPEK------------------AERVVNELVRYLS 290 Query: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428 V + +D+ + G I G ++ ++ +DEA+ P + Sbjct: 291 PVQAPNPRLAIKDVVIDGQLIKAGDYVLCSILMANRDEALTPDPDVLDANRAAVSD---- 346 Query: 429 KPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS---FSVPTGQ 472 + F G C+G LAR L + + +L + F +VP + Sbjct: 347 -----VGFGHGIHYCVGAALARSMLRMAYQTLWRRFPGLRLAVPIEE 388 >5HIW-A nrPDB Length = 398 Score = 158 bits (399), Expect = 6e-39, Method: Composition-based stats. Identities = 87/411 (21%), Positives = 140/411 (34%), Gaps = 69/411 (16%) Query: 79 VVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVST 138 VVL G V A++ E + R +G + G A RR + Sbjct: 41 VVLRGADVV--AVLRDSETFSTRT--------YDTGIMKGALVTLGGEAHTRMRRLFNAV 90 Query: 139 LRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYD 198 L + + + E VT A + + + V ++ Sbjct: 91 L-SPRVISRYEEATVTPVARRVVERLVRKERAELFDDFAIS-MPMGVTSA---------- 138 Query: 199 DPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEH 258 L L +E + E +R+++ +V V+ P + + A QL E+ Sbjct: 139 ------LFGLPEERIAENDALIRKMIRSV-VMPQDPVVVAEGRSAHAAMEAQLREIAER- 190 Query: 259 RMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGL 318 + A P ++ L E+ +A E E VV L TTS LA L Sbjct: 191 ----EVAHP----SDTLLGEIARAIV-AEGLGGVEACEGVVLTLILGSYETTSWMLANLL 241 Query: 319 LLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMT 378 + ++ HPD +++Q+ I E R+ G+ Sbjct: 242 VALLAHPDAMNQLRQQPS------------------LLPQAIEESTRWCSSAA-GIVRFV 282 Query: 379 SRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSA 438 R+ + G + GT L +L + DE ++ +P F +P L F Sbjct: 283 EREATIGGETLAAGTILYLSLIARHYDEEIYPRPETFDIHR---------RPVGMLNFGG 333 Query: 439 GRRACLGEPLARMELFLFFTSLLQHFSF--SVPTGQPRPSHHGVFAFLVSP 487 G C+G PLARME + + LL+ F + PT QP S A P Sbjct: 334 GLHYCVGAPLARMEARVGVSLLLERFPALRADPTVQPTFSTAPRGAAAFGP 384 >4TX3-A nrPDB Length = 404 Score = 157 bits (398), Expect = 7e-39, Method: Composition-based stats. Identities = 73/390 (18%), Positives = 120/390 (30%), Gaps = 74/390 (18%) Query: 83 GLAAVREALVTHGEDTADRPPVPITQIL----GFGPRSQGVFLARYGPAWREQRRFSVST 138 G A VR+ L H + R + F PR L Y P E R Sbjct: 53 GHAVVRQVLGDHKR-FSTRRRFDRRDEIGGTGVFRPRELVGNLMDYDP--PEHTRLRH-- 107 Query: 139 LRNLGLGKKSLEQWVTEEAACLCAAF--ANHSGRPFRPNGLL-DKAVSNVIASLTCGRRF 195 L G ++ + + + +G P L D+ V+ L R Sbjct: 108 LLTPGFTQRRMRRLAPRIEEIVTDRLDAMEQAGPPADLIELFADEVPGAVLCELIGVPR- 166 Query: 196 EYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELL 255 D FL+L + A K +AF L ++ Sbjct: 167 -DDQAMFLQLCHRHLDAS---------------------LSARKRAAAGEAFARYLVAMM 204 Query: 256 TEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLA 315 R D + F+ + G+ + DE LR V L AG S + Sbjct: 205 ARERK---------DPGDGFIGSIVAEHGD---TITDEELRGVCVQLMLAGDDNVSGMIG 252 Query: 316 WGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVT 375 G+L ++ HP+ ++ + + E+ R+ + Sbjct: 253 LGVLALLRHPEQIAALRGDDQS------------------ADRAVDELIRYLTVPYAPTP 294 Query: 376 HMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLP 435 D+ V I +G T++ +L +D A+ R P + Sbjct: 295 RTAVEDVMVADQVIKEGETVLCSLPMANRDRALLPDADRLDVTR---------TPVPHVA 345 Query: 436 FSAGRRACLGEPLARMELFLFFTSLLQHFS 465 F G CLG L R++L + +T+L + F Sbjct: 346 FGHGIHHCLGAALTRLQLRIAYTALWRRFP 375 >4ZGX-A nrPDB Length = 489 Score = 157 bits (398), Expect = 7e-39, Method: Composition-based stats. Identities = 70/417 (16%), Positives = 135/417 (32%), Gaps = 29/417 (6%) Query: 46 LLHV----DFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADR 101 LL + +++ Q + G +F L +V + V + + Sbjct: 29 LLQIWREQGYEHLHLEMHQTFQELGPIFRYNLGGPRMVCVMLPEDVE----KLQQVDSLH 84 Query: 102 PPVPITQILGFGPRSQGV---FLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAA 158 P I + + +G GP WR R + + ++ L V A Sbjct: 85 PCRMILEPWVAYRQHRGHKCGVFLLNGPEWRFNRLRLNPDVLSPKAVQRFL-PMVDAVAR 143 Query: 159 CLCAAFANH------SGRPFRPNGLLDKAVSNVIASLTCGRRFEY-DDPRFLRLLDLAQE 211 A + G R L+ Sbjct: 144 DFSQALKKKVLQNARGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHA 203 Query: 212 GLKEESGFLREVLNAVPVLLHI-PALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRD 270 ++ + + I P + + D + + +P Sbjct: 204 LEVMFKSTVQLMFMPRSLSRWISPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFNRPQH- 262 Query: 271 LTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRR 330 +AE+ + + E ++ +L + + TT+ L L + +PDVQ+ Sbjct: 263 -YTGIVAELLLK-----AELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQI 316 Query: 331 VQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIP 390 ++QE + +P A + E R V L + + S D+ +Q + IP Sbjct: 317 LRQESLAAAASISEHPQKATTELPLLRAALKETLRLYP-VGLFLERVVSSDLVLQNYHIP 375 Query: 391 KGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEP 447 GT + L S+ ++ A++ +P R++P+ +LD +G + +PF G R CLG Sbjct: 376 AGTLVQVFLYSLGRNAALFPRPERYNPQRWLDIRG-SGRNFHHVPFGFGMRQCLGRR 431 >3NC3-A nrPDB Length = 441 Score = 157 bits (398), Expect = 7e-39, Method: Composition-based stats. Identities = 74/422 (17%), Positives = 136/422 (32%), Gaps = 56/422 (13%) Query: 45 NLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPV 104 ++L FQN PY + R V ++ VR L H + + V Sbjct: 45 SVLSDQFQNNPYAYFSQLREEDPVH--YEESIDSYFISRYHDVRYIL-QHPDIFTTKSLV 101 Query: 105 PITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAF 164 + + GP V +G +RR V + +G L + + A L A + Sbjct: 102 ERAEPVMRGP----VLAQMHGKEHSAKRRIVVRSF--IGDALDHLSPLIKQNAENLLAPY 155 Query: 165 ANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVL 224 + AV + L +R S + V Sbjct: 156 LERGKSDLVNDFGKTFAVCVTMDMLGLDKRDHEK-----------------ISEWHSGVA 198 Query: 225 NAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKG 284 + + + P L + L ++ E R P DL + Sbjct: 199 DFITSISQSPEARAHSLWCSEQLSQYLMPVIKERR-----VNPGSDLISILCTSEYEG-- 251 Query: 285 NPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344 + +D+++ ++ ++ A TLA + ++ +P+ V Sbjct: 252 ---MALSDKDILALILNVLLAATEPADKTLALMIYHLLNNPEQMNDV------------- 295 Query: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404 + D++ +P I E R+ V L + S+D V G I K T + + + + Sbjct: 296 --LADRSLVP---RAIAETLRYKPPVQL-IPRQLSQDTVVGGMEIKKDTIVFCMIGAANR 349 Query: 405 DEAVWEKPFRFHPEH-FLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQH 463 D +E+P F+ L + F L F +G C+G A+ E+ + +L Sbjct: 350 DPEAFEQPDVFNIHREDLGIKSAFSGAARHLAFGSGIHNCVGTAFAKNEIEIVANIVLDK 409 Query: 464 FS 465 Sbjct: 410 MR 411 >1LG9-A nrPDB Length = 398 Score = 157 bits (396), Expect = 1e-38, Method: Composition-based stats. Identities = 77/414 (18%), Positives = 127/414 (30%), Gaps = 87/414 (21%) Query: 84 LAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLA----------RYGPAWREQRR 133 A VR+ + H + + R +G +G+F R +R+ Sbjct: 48 HAVVRQVMGDH-QQFSTRRRWDPRDEIG----GKGIFRPRELVGNLMDYDPPEHTRLRRK 102 Query: 134 FSVS-TLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFR-PNGLLDKAVSNVIASLTC 191 + TLR + +EQ V + + +G P + DK V+ L Sbjct: 103 LTPGFTLRKMQRMAPYIEQIVNDRLDEM-----ERAGSPADLIAFVADKVPGAVLCELVG 157 Query: 192 GRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQL 251 R D F++L + + F L Sbjct: 158 VPR--DDRDMFMKLCHGHLDAS---------------------LSQKRRAALGDKFSRYL 194 Query: 252 DELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTS 311 ++ R +P + A +AE DE LR + AG S Sbjct: 195 LAMIARERK-----EPGEGMIGAVVAEY-------GDDATDEELRGFCVQVMLAGDDNIS 242 Query: 312 TTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVP 371 + G+L M+ HP+ ID G + + E+ R+ + Sbjct: 243 GMIGLGVLAMLRHPEQ-------IDAFRGDEQS-----------AQRAVDELIRYLTVPY 284 Query: 372 LGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPE 431 + D+ + G I KG ++I +L + +D A+ R +P Sbjct: 285 SPTPRIAREDLTLAGQEIKKGDSVICSLPAANRDPALAPDVDRLDVTR---------EPI 335 Query: 432 AFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLV 485 + F G CLG LAR+EL FT L + F P+ F Sbjct: 336 PHVAFGHGVHHCLGAALARLELRTVFTELWRRFPALRLA---DPAQDTEFRLTT 386 >6M7X-A nrPDB Length = 484 Score = 157 bits (396), Expect = 1e-38, Method: Composition-based stats. Identities = 74/444 (16%), Positives = 142/444 (31%), Gaps = 32/444 (7%) Query: 23 MHRRQRWAAR--YP-------PGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQL 73 M ++ R P PG L L +++ Q + G +F L Sbjct: 1 MAKKTSSVPRTVLPFEAMPRRPGNRWLRLLQIWREQGYEDLHLEVHQTFQELGPIFRYDL 60 Query: 74 AWTPVVVLNGLAAVREALVTHGEDTADR--PPVPITQILGFGPRSQGVFLARYGPAWREQ 131 +V + V + + + P GVFL GP WR Sbjct: 61 GGAGMVCVMLPEDVEK--LQQVDSLHPHRMSLEPWVAYRQHRGHKCGVFLLN-GPEWRFN 117 Query: 132 RRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANH------SGRPFRPNGLLDKAVSNV 185 R + + ++ L V A A + Sbjct: 118 RLRLNPEVLSPNAVQRFL-PMVDAVARDFSQALKKKVLQNARGSLTLDVQPSIFHYTIEA 176 Query: 186 IASLTCGRRFEY-DDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHI-PALAGKVLRF 243 G R L+ ++ + + P + + Sbjct: 177 SNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFMPRSLSRWTSPKVWKEHFEA 236 Query: 244 QKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLF 303 D + + ++P + + +AE+ + + + ++ +L Sbjct: 237 WDCIFQYGDNCIQKIYQELAFSRPQQ--YTSIVAELL-----LNAELSPDAIKANSMELT 289 Query: 304 SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEV 363 + + TT L L + +P+VQ+ ++QE + +P A + E Sbjct: 290 AGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLRAALKET 349 Query: 364 QRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDA 423 R V L + + S D+ +Q + IP GT + L S+ ++ A++ +P R++P+ +LD Sbjct: 350 LRLYP-VGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDI 408 Query: 424 QGHFVKPEAFLPFSAGRRACLGEP 447 +G + +PF G R CLG Sbjct: 409 RG-SGRNFYHVPFGFGMRQCLGRR 431 >5DQN-A nrPDB Length = 426 Score = 156 bits (395), Expect = 1e-38, Method: Composition-based stats. Identities = 44/229 (19%), Positives = 76/229 (33%), Gaps = 41/229 (17%) Query: 246 AFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSA 305 ++ ++ E P D+ + + +D+ V L A Sbjct: 202 ELISYAMKMAEER-----AVNPTEDIVTKLIEADIDGE-----KLSDDEFGFFVVMLAVA 251 Query: 306 GMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQR 365 G TT ++ G++ +PD ++E E+ R Sbjct: 252 GNETTRNSITHGMIAFAQNPDQWELYKKERP--------------------ETAADEIVR 291 Query: 366 FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQG 425 + V D+E+ G +I KG ++ + S DE V+E P F+ Sbjct: 292 WATPVS-AFQRTALEDVELGGVQIKKGQRVVMSYRSANFDEEVFEDPHTFNILR------ 344 Query: 426 HFVKPEAFLPFSA-GRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQP 473 P + F G C+G LARM + L F ++ + P G P Sbjct: 345 ---SPNPHVGFGGTGAHYCIGANLARMTINLIFNAIADNMPDLKPIGAP 390 >5XJN-A nrPDB Length = 455 Score = 155 bits (392), Expect = 3e-38, Method: Composition-based stats. Identities = 63/425 (14%), Positives = 128/425 (30%), Gaps = 74/425 (17%) Query: 50 DFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTAD--------- 100 D N + +LR+ +F ++ V+ ++ E + Sbjct: 60 DMHNPFPAYKELRQEEPVMFDERIG---YWVVTKYDDIKTTF-DDWETFSSENAQAPVRK 115 Query: 101 RPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACL 160 R P + G + AR P R + K+LE + Sbjct: 116 RGPQATQIMTDGGFTAYSGLSARIPPEHTRIRAIAQKAFTP--RRYKALEPDIRAMVIDR 173 Query: 161 CAAFANHSGRPFRPNGLLDKAVSNV---IASLTCGRRFEYDDPRFLRLLDLAQEGLKEES 217 + + VS++ I ++T D + ++D + + Sbjct: 174 VEKM-------LANDQHVGDMVSDLAYDIPTITILTLIGAD----ISMVDTYKRWSDSRA 222 Query: 218 GFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLA 277 L+ + H L Q+ A +LT + Sbjct: 223 AMTWGDLSDEEQIPHAHNLVEYWQECQRMVADA-------------HAHGGDNLTADLVR 269 Query: 278 EMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDD 337 ++ + D + ++ L AG TT+T ++ +++ HP+ + + + Sbjct: 270 AQQEGQ-----EITDHEIASLLYSLLFAGHETTTTLISNCFRVLLDHPEQWQAILENP-- 322 Query: 338 VIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLIT 397 A + EV R+ + +G +D E+ G I +G ++ Sbjct: 323 ----------------KLIPAAVDEVLRYSGSI-VGWRRKALKDTEIGGVAIKEGDGVLL 365 Query: 398 NLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFF 457 + S +DEA +E F L F G CLG LA+++ + Sbjct: 366 LMGSANRDEARFENGEEFDISR--------ANAREHLSFGFGIHYCLGNMLAKLQAKICL 417 Query: 458 TSLLQ 462 + + Sbjct: 418 EEVTR 422 >5GWE-A nrPDB Length = 405 Score = 155 bits (392), Expect = 4e-38, Method: Composition-based stats. Identities = 63/425 (14%), Positives = 128/425 (30%), Gaps = 74/425 (17%) Query: 50 DFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTAD--------- 100 D N + +LR+ +F ++ V+ ++ E + Sbjct: 10 DMHNPFPAYKELRQEEPVMFDERIG---YWVVTKYDDIKTTF-DDWETFSSENAQAPVRK 65 Query: 101 RPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACL 160 R P + G + AR P R + K+LE + Sbjct: 66 RGPQATQIMTDGGFTAYSGLSARIPPEHTRIRAIAQKAFTP--RRYKALEPDIRAMVIDR 123 Query: 161 CAAFANHSGRPFRPNGLLDKAVSNV---IASLTCGRRFEYDDPRFLRLLDLAQEGLKEES 217 + + VS++ I ++T D + ++D + + Sbjct: 124 VEKM-------LANDQHVGDMVSDLAYDIPTITILTLIGAD----ISMVDTYKRWSDSRA 172 Query: 218 GFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLA 277 L+ + H L Q+ A +LT + Sbjct: 173 AMTWGDLSDEEQIPHAHNLVEYWQECQRMVADA-------------HAHGGDNLTADLVR 219 Query: 278 EMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDD 337 ++ + D + ++ L AG TT+T ++ +++ HP+ + + + Sbjct: 220 AQQEGQ-----EITDHEIASLLYSLLFAGHETTTTLISNCFRVLLDHPEQWQAILENP-- 272 Query: 338 VIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLIT 397 A + EV R+ + +G +D E+ G I +G ++ Sbjct: 273 ----------------KLIPAAVDEVLRYSGSI-VGWRRKALKDTEIGGVAIKEGDGVLL 315 Query: 398 NLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFF 457 + S +DEA +E F L F G CLG LA+++ + Sbjct: 316 LMGSANRDEARFENGEEFDISR--------ANAREHLSFGFGIHYCLGNMLAKLQAKICL 367 Query: 458 TSLLQ 462 + + Sbjct: 368 EEVTR 372 >4MM0-A nrPDB Length = 399 Score = 155 bits (391), Expect = 4e-38, Method: Composition-based stats. Identities = 61/396 (15%), Positives = 114/396 (28%), Gaps = 67/396 (16%) Query: 71 LQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWRE 130 P ++ VR L + R +P L + P Sbjct: 40 TMATGDPGFLVTRYEDVRFVLSD--PRFSVRQDLPGAPRLTEMTFES--VMTTDPPVHTR 95 Query: 131 QRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDK-AVSNVIASL 189 RR + + + + E A L G P L VI Sbjct: 96 LRRLLSRDFTARRIER--MRPRLEEIAEGLLDEMEK-KGAPADIVESLAVPFPITVIC-- 150 Query: 190 TCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLT 249 LL + + G+ +++ + + A + Sbjct: 151 --------------ELLGVPMVDVARFRGWADTMVSLTGYSM------EDWTAARDALES 190 Query: 250 QLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVT 309 LD L+ R P DL A +A + ++ D ++R + L AG Sbjct: 191 YLDGLVAAKRE-----NPGSDLLSALVATAAE-----DNELTDHDVRSLSLILLLAGYEP 240 Query: 310 TSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDI 369 S L +L ++ PD ++++ + + E+ R+ Sbjct: 241 ASNQLGSSVLTLLRFPDRLAELRRDPG------------------LLPSAVEELMRYAPA 282 Query: 370 VPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVK 429 + +T D+ + IP + ++ + + D ++ P + Sbjct: 283 GDGALFRVTLEDVTIGDTHIPANSAVLASTQAANWDPRRFDDPTGLRLDR---------P 333 Query: 430 PEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465 G CLG LAR+EL + +LL+ F Sbjct: 334 DNQHTALGHGIHFCLGAALARVELQVAIGALLRRFP 369 >3MGX-A nrPDB Length = 415 Score = 154 bits (389), Expect = 8e-38, Method: Composition-based stats. Identities = 64/395 (16%), Positives = 117/395 (29%), Gaps = 81/395 (20%) Query: 95 GEDTADRPPVPITQILGFGPRSQGVFLA-------RYGPAWR------EQRRF--SVSTL 139 + R + G+ + G + R+ V L Sbjct: 65 WSVFSHRACAAVLAPSAPLTSEYGMMIGFDRDHPDNSGGRMMVVSEHEQHRKLRKLVGPL 124 Query: 140 RNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLD-KAVSNVIASLTCGRRFEYD 198 + +K E+ E L G + + + V+ + + Sbjct: 125 LSRAAARKLAERVRIEVGDVLGRVL---DGEVCDAATAIGPRIPAAVVCEI---LGVPAE 178 Query: 199 DPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEH 258 D L +DL E + + L DEL+T Sbjct: 179 DEDML--IDLTNHAFGGEDELFDGM---------------TPRQAHTEILVYFDELITAR 221 Query: 259 RMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGL 318 R +P DL + + +++ + ++ G TT + + Sbjct: 222 RK-----EPGDDLVSTLVT---------DDDLTIDDVLLNCDNVLIGGNETTRHAITGAV 267 Query: 319 LLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMT 378 + P + ++ DV V+ EV R+ + V +T Sbjct: 268 HALATVPGLLTALRDGSADV------------------DTVVEEVLRWTSPA-MHVLRVT 308 Query: 379 SRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSA 438 + D+ + G +P GT ++ L + +D A ++ P F P KP + F Sbjct: 309 TADVTINGRDLPSGTPVVAWLPAANRDPAEFDDPDTFLPGR---------KPNRHITFGH 359 Query: 439 GRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQP 473 G CLG LAR+EL + L + S +P Sbjct: 360 GMHHCLGSALARIELSVVLRVLAERVSRVDLEREP 394 >6F0B-A nrPDB Length = 395 Score = 154 bits (388), Expect = 1e-37, Method: Composition-based stats. Identities = 66/393 (16%), Positives = 129/393 (32%), Gaps = 65/393 (16%) Query: 75 WTPVVVLNGLAAVREALVTHG-EDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRR 133 TP V +G VR L + RP + F+ P + RR Sbjct: 37 GTPAHVFSGYEDVRTVLQDRRFSSDSRRPNFTELTPTLQSQAAAPPFVRTDNP---DHRR 93 Query: 134 FSVSTLRNLGLGK-KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCG 192 + R + L + E + A + P +L+ V ++ Sbjct: 94 LRGTIAREFLPKHIELLRPAIREIVQGVLDGLAETA----PPQDMLEAFAVPVASATVF- 148 Query: 193 RRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLD 252 RLL + E + ++ V++AV + + + Sbjct: 149 -----------RLLGIPAEDRALLTRCVKGVVSAV-------GSEDEGAEVFRTLGEYIG 190 Query: 253 ELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTST 312 L+ DP++ P D + + + E V+ L G TT++ Sbjct: 191 GLVQ------DPSELPED---SLIRRLVTGPY-QEKQLTFHETIGVILMLIVGGYDTTAS 240 Query: 313 TLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPL 372 T++ L+ L P+ V + + + ++ E+ R+ + L Sbjct: 241 TISLSLVSYALQPEKFSVVHEHPERI------------------PLLVEELLRYHTVSQL 282 Query: 373 GVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEA 432 G+ + + D+EV G + G ++ L +DE+V+ P + Sbjct: 283 GLGRIATEDVEVGGVTVRAGQMVVAALPLANRDESVFPNPDELDFDR---------PSVP 333 Query: 433 FLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465 + F G C+G+ LAR+EL ++++ Sbjct: 334 HVGFGYGPHQCVGQALARVELQEAIPAVIRRLP 366 >4TRI-A nrPDB Length = 407 Score = 153 bits (387), Expect = 1e-37, Method: Composition-based stats. Identities = 49/260 (18%), Positives = 88/260 (33%), Gaps = 41/260 (15%) Query: 238 GKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRI 297 K++ A+ +++T+ R A+P DL + + + +D+ + Sbjct: 176 QKLMDTFAAYTEFTKDVITKRR-----AEPTDDLFSVLVNSEVEGQ-----RMSDDEIVF 225 Query: 298 VVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTT 357 + G TT TL+ G ++ H D + ++D Sbjct: 226 ETLLILIGGDETTRHTLSGGTEQLLRHRDQWDALVADVD------------------LLP 267 Query: 358 AVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHP 417 I E+ R+ V + + D G + G ++ S DE+V+ P F Sbjct: 268 GAIEEMLRWTSPVK-NMCRTLTADTVFHGTELRAGEKIMLMFESANFDESVFGDPDNFRI 326 Query: 418 EHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF-SFSVPTGQPRPS 476 + P + + F G CLG LAR+EL L +L+ + P P Sbjct: 327 DR---------NPNSHVAFGFGTHFCLGNQLARLELRLMTERVLRRLPDLRLADDAPVPL 377 Query: 477 HHGVFAFLVSPSPYELCAVP 496 F + P + P Sbjct: 378 RPANF--VSGPESMPVVFTP 395 >4Z5Q-A nrPDB Length = 423 Score = 152 bits (385), Expect = 3e-37, Method: Composition-based stats. Identities = 70/447 (15%), Positives = 129/447 (28%), Gaps = 84/447 (18%) Query: 35 PGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVF------SLQL-AWTPVVVLNGLAAV 87 P P+ P G+ +L + + +F +QL P ++ Sbjct: 33 PAPVAYPFTGS-----------EGLELSQSYAKLFEDGDPIRVQLPFGEPAWLVTRYDDA 81 Query: 88 REALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKK 147 R L + + L P R + + Sbjct: 82 RFVLTDR--RFSRHLATQRDEPRMTPRAVPESILTMDPPDHTRLRTLVSKAFTPRRI--E 137 Query: 148 SLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLR-LL 206 S W+ E AA L A VI L DD LR Sbjct: 138 SKRAWIGELAAGLVADMKAGGAPAELVGSYALAIPVTVICEL---LGVPEDDRTRLRGWC 194 Query: 207 DLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQ 266 D A + + ++ ++L+ E R A+ Sbjct: 195 DAALSTGELTD--------------------EECVQSFMDLQKYFEDLVKERR-----AE 229 Query: 267 PPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPD 326 P DLT A + + + L + + G TT++ ++ + ++ + Sbjct: 230 PRDDLTSALIEAR-----DAHDRLAEPELIGLCISILIGGFETTASEISSFVHVLQQRRE 284 Query: 327 VQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGV-THMTSRDIEVQ 385 + R+ + + + A + E+ RF G+ D+ V Sbjct: 285 LWTRLCADPEAI------------------PAAVEELLRFVPFAANGISPRYALEDMTVG 326 Query: 386 GFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLG 445 G + +G +I + S+V +D V++ + + F G CLG Sbjct: 327 GVLVREGEPVIVDTSAVNRDGLVFDNADEVVIDR---------ADNRHMVFGHGAHHCLG 377 Query: 446 EPLARMELFLFFTSLLQHFSFSVPTGQ 472 LAR+EL +L++ +G Sbjct: 378 AHLARVELQEALKALVEGMPGLRLSGD 404 >3SN5-A nrPDB Length = 491 Score = 151 bits (380), Expect = 9e-37, Method: Composition-based stats. Identities = 79/505 (15%), Positives = 147/505 (29%), Gaps = 56/505 (11%) Query: 23 MHRRQRWAARY---PPGPLPL-PGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPV 78 M ++ R PP L P LG L N +R+ G VF+ +L V Sbjct: 1 MAKKTSSRRRQTGEPPLENGLIPYLGCALQFG-ANPLEFLRANQRKHGHVFTCKLMGKYV 59 Query: 79 VVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVST 138 + + + L HG+ + FG RS + + T Sbjct: 60 HFITNPLSYHKVLC-HGKYFDWKKFHFALSAKAFGHRSIDPMDGNTTENINDT---FIKT 115 Query: 139 LRNLGLGK--KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLT-CGRRF 195 L+ L +S+ + + ++ + + V LT GR Sbjct: 116 LQGHALNSLTESMMENLQRIMRPPVSSNSKTAAWVTEGMYSFCYRVMFEAGYLTIFGRDL 175 Query: 196 EYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELL 255 D + +L+ + K+ ++ +P+ + ++ L Sbjct: 176 TRRDTQKAHILNNL-DNFKQFDKVFPALVAGLPIHMF-----RTAHNAREKLAESLRHEN 229 Query: 256 TEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLA 315 + R + R L S+F+D + A T Sbjct: 230 LQKRESISELISLRMFLNDTL-----------STFDDLEKAKTHLVVLWASQANTIPATF 278 Query: 316 WGLLLMILHPDVQRRVQQEIDDVI----------GQVRRPEMGDQAHMPYTTAVIHEVQR 365 W L MI +P+ + +E+ + G + +P ++I E R Sbjct: 279 WSLFQMIRNPEAMKAATEEVKRTLENAGQKVSLEGNPICLSQAELNDLPVLDSIIKESLR 338 Query: 366 FGDIVPLGVTHMTSRDIEV----QGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFL 421 D + + I K + + D ++ P F + +L Sbjct: 339 LSSAS--LNIRTAKEDFTLHLEDGSYNIRKDDIIALYPQLMHLDPEIYPDPLTFKYDRYL 396 Query: 422 DAQGHFVK---------PEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQ 472 D G ++PF +G C G A E+ F +L +F + GQ Sbjct: 397 DENGKTKTTFYCNGLKLKYYYMPFGSGATICPGRLFAIHEIKQFLILMLSYFELELIEGQ 456 Query: 473 PR--PSHHGVFAFLVSPSPYELCAV 495 + P + P ++ Sbjct: 457 AKCPPLDQSRAGLGILPPLNDIEFK 481 >2WM5-A nrPDB Length = 435 Score = 151 bits (380), Expect = 1e-36, Method: Composition-based stats. Identities = 62/384 (16%), Positives = 117/384 (30%), Gaps = 60/384 (15%) Query: 93 THGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQW 152 H + + P + I G + P + R + + +E Sbjct: 90 RHPDIFSSYPNITINDQTPELAEYFGSMIVLDDPRHQRLRSIVSRAFTPKVVAR--IEAA 147 Query: 153 VTEEAACLCAAF-ANHSGRPFRP-NGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQ 210 V + A L ++ AN+ R + L +I + + ++ R+ Sbjct: 148 VRDRAHRLVSSMIANNPDRQADLVSELAGPLPLQIICDMMGIPKADHQ-----RIFHWTN 202 Query: 211 EGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRD 270 L L + ++ L + R D Sbjct: 203 VILGFGDPDLATDFDEF-------------MQVSADIGAYATALAEDRR-----VNHHDD 244 Query: 271 LTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRR 330 LT + + + + + L AG TT + G+L + +P+ + R Sbjct: 245 LTSSLVEAEVDGE-----RLSSREIASFFILLVVAGNETTRNAITHGVLALSRYPEQRDR 299 Query: 331 VQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIP 390 + D + E+ R+ V + + ++DIE++G ++ Sbjct: 300 WWSDFDG-----------------LAPTAVEEIVRWASPV-VYMRRTLTQDIELRGTKMA 341 Query: 391 KGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPF-SAGRRACLGEPLA 449 G + S +DE+ + P+ F P L F G CLG LA Sbjct: 342 AGDKVSLWYCSANRDESKFADPWTFDLAR---------NPNPHLGFGGGGAHFCLGANLA 392 Query: 450 RMELFLFFTSLLQHFSFSVPTGQP 473 R E+ + F L + V T +P Sbjct: 393 RREIRVAFDELRRQMPDVVATEEP 416 >1Q5D-A nrPDB Length = 419 Score = 149 bits (376), Expect = 3e-36, Method: Composition-based stats. Identities = 64/407 (15%), Positives = 120/407 (29%), Gaps = 59/407 (14%) Query: 80 VLNGLAAVREALVTHGEDTADRP----PVPITQILGFGPRSQGVFLARYGPAWREQRRFS 135 VL V + + I + R+ Sbjct: 51 VLTRYHDVSAVFRDERFAVSREEWESSAEYSSAIPELSDMKKYGLFGLPPEDHARVRKLV 110 Query: 136 VSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRF 195 + + + + E + + + D A + +++ + Sbjct: 111 NPSFTSRAI------DLLRAEIQRTVDQLLDARSGQEEFDVVRDYAEGIPMRAISALLKV 164 Query: 196 EYD-DPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDEL 254 + D +F R G V ++ + ++ L L + Sbjct: 165 PAECDEKFRRF------------GSATARALGVGLVPRVDEETKTLVASVTEGLALLHGV 212 Query: 255 LTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTL 314 L E R P + L + E S + + L +V + +AG TT + Sbjct: 213 LDERRR-----NPLENDVLTMLLQAEA----DGSRLSTKELVALVGAIIAAGTDTTIYLI 263 Query: 315 AWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGV 374 A+ +L ++ P+ V+ E + EV RF +I+ +G Sbjct: 264 AFAVLNLLRSPEALELVKAEPG------------------LMRNALDEVLRFDNILRIGT 305 Query: 375 THMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFL 434 +D+E G I KG + + S L+D V+ +P F A L Sbjct: 306 VRFARQDLEYCGASIKKGEMVFLLIPSALRDGTVFSRPDVFDVRR---------DTSASL 356 Query: 435 PFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVF 481 + G C G LAR+E + ++ + F P +H F Sbjct: 357 AYGRGPHVCPGVSLARLEAEIAVGTIFRRFPEMKLKETPVFGYHPAF 403 >6CVC-A nrPDB Length = 433 Score = 149 bits (375), Expect = 4e-36, Method: Composition-based stats. Identities = 66/397 (16%), Positives = 123/397 (30%), Gaps = 61/397 (15%) Query: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTL 139 L + A H E P + I G + P + R Sbjct: 75 ALTKHDDIHFA-SRHPEIFHSSPNIVIHDQTPELAEYFGSMIVLDDPRHQRLRSIVSRAF 133 Query: 140 RNLGLGKKSLEQWVTEEAACLCAAF-ANHSGRPFRP-NGLLDKAVSNVIASLTCGRRFEY 197 + + +E V E A L AA NH + L +I Sbjct: 134 TPKVVAR--IEASVRERAHRLVAAMIENHPDGQADLVSELAGPLPLQIIC---------- 181 Query: 198 DDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTE 257 ++ + +E ++ + +L + + L+ A L + Sbjct: 182 ------DMMGIPEEDHEQIFHWTNVILGFGD--PDLTTDFDEFLQVSMAIGGYATALADD 233 Query: 258 HRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWG 317 R DLT + + + + + + L AG TT ++ G Sbjct: 234 RR-----VNHHGDLTTSLVEAEVDGE-----RLSSSEIAMFFILLVVAGNETTRNAISHG 283 Query: 318 LLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHM 377 +L + +PD + + + D + + E+ R+ V + + Sbjct: 284 MLALSRYPDERAKWWSDFDGLAA-----------------TAVEEIVRWASPV-VYMRRT 325 Query: 378 TSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPF- 436 S+D++++G ++ G + S +DE + P+ F P + F Sbjct: 326 LSQDVDLRGTKMAAGDKVTLWYCSANRDEEKFADPWTFDVTR---------NPNPQVGFG 376 Query: 437 SAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQP 473 G CLG LAR E+ + F L + V T +P Sbjct: 377 GGGAHFCLGANLARREIRVVFDELRRQMPDVVATEEP 413 >3IVY-A nrPDB Length = 433 Score = 148 bits (373), Expect = 6e-36, Method: Composition-based stats. Identities = 45/230 (19%), Positives = 75/230 (32%), Gaps = 41/230 (17%) Query: 245 KAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFS 304 + ++ E P D+ + + +D+ V L Sbjct: 218 AELIGYAMKMAEEKAK-----NPADDIVTQLIQADIDGE-----KLSDDEFGFFVVMLAV 267 Query: 305 AGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQ 364 AG TT ++ G++ HPD + +++ E+ Sbjct: 268 AGNETTRNSITQGMMAFAEHPDQWE-LYKKVR-------------------PETAADEIV 307 Query: 365 RFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQ 424 R+ V RD E+ G +I KG ++ S DE V++ PF F+ Sbjct: 308 RWATPV-TAFQRTALRDYELSGVQIKKGQRVVMFYRSANFDEEVFQDPFTFNILR----- 361 Query: 425 GHFVKPEAFLPFSA-GRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQP 473 P + F G C+G LARM + L F ++ H P P Sbjct: 362 ----NPNPHVGFGGTGAHYCIGANLARMTINLIFNAVADHMPDLKPISAP 407 >6HQG-A nrPDB Length = 425 Score = 147 bits (370), Expect = 1e-35, Method: Composition-based stats. Identities = 63/385 (16%), Positives = 118/385 (30%), Gaps = 56/385 (14%) Query: 96 EDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTE 155 E + P + + + + P QR+ + L LE + E Sbjct: 80 EVFSSEPTIVLPDPADDFTLPMFIAMD--PPKHDVQRKTVQPIVAPNHLA--YLEPIIRE 135 Query: 156 EAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKE 215 A + P VS + ++T F++ +L Sbjct: 136 RAGKILDDL------PIGEEINWVDKVSIELTTMTLATLFDFPWEDRRKL---------- 179 Query: 216 ESGFLREVLNAVPVLLHIPAL-AGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEA 274 F +V + P + + ++ L + + A P DL Sbjct: 180 --TFWSDVATSAPESGILGTTDPEEHENLRRQTLFECVDYFMRLWNERVNAPPKPDLISM 237 Query: 275 FLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQE 334 A G + + + L G TT T++ +L + +PD R++++ Sbjct: 238 L------AHGESTKNMDRMEYLGNLILLIVGGNDTTRNTISGSVLALHQNPDQDRKLREN 291 Query: 335 IDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTT 394 A++ E R+ + + RD E+ G I +G Sbjct: 292 PG------------------LIPAMVSETIRWQTPLAY-MRRRAKRDFELGGKTIREGDK 332 Query: 395 LITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELF 454 + S +DE V ++P + E + L F G C+G LA ++L Sbjct: 333 VAMWYVSGNRDEEVIDRPNDYWIER--------PRVRQHLSFGFGVHRCVGNRLAELQLK 384 Query: 455 LFFTSLLQHFSFSVPTGQPRPSHHG 479 + + +L F G PR + Sbjct: 385 IIWEEILARFPRLEVVGPPRRVYSS 409 >2RFC-A nrPDB Length = 343 Score = 145 bits (366), Expect = 4e-35, Method: Composition-based stats. Identities = 37/190 (19%), Positives = 63/190 (33%), Gaps = 31/190 (16%) Query: 276 LAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEI 335 + + + + L G TT+ + + ++ +PD+ I Sbjct: 159 IINVLAGSSLKNRKLTMDEKIKYIMLLIIGGNETTTNLIGNMIRVIDENPDI-------I 211 Query: 336 DDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTL 395 DD + + E R+ + + D + +I KG + Sbjct: 212 DDALKNRS--------------GFVEETLRYYSPIQFLPHRFAAEDSYINNKKIKKGDQV 257 Query: 396 ITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFL 455 I L S +DE +++P F E L F G CLG PLAR+E + Sbjct: 258 IVYLGSANRDETFFDEPDLFKIGR----------REMHLAFGIGIHMCLGAPLARLEASI 307 Query: 456 FFTSLLQHFS 465 +L HF Sbjct: 308 ALNDILNHFK 317 >5L1U-A nrPDB Length = 401 Score = 144 bits (363), Expect = 8e-35, Method: Composition-based stats. Identities = 61/422 (14%), Positives = 123/422 (29%), Gaps = 75/422 (17%) Query: 63 RRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTA---DRPPVPITQILGFGPRSQGV 119 ++ G + + A ++ VR L + +P + G Sbjct: 28 QKEGPIARVGTAGEDAWLVTRYDEVRTLLADRRLRLSNPNPQPSAKSAARAFMVALAAGD 87 Query: 120 FLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLL- 178 + R + L + ++ + L A P + +L Sbjct: 88 DHETEPARHAQMRSLLIPRFSTRRL--RLMKTRIEHHVDELLDQLAAS-APPVDLHRVLS 144 Query: 179 DKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAG 238 + + V+ LL + + + R + Sbjct: 145 FRLPTMVVC----------------DLLGVPLADRERFGQWARGTFDQSD--------NE 180 Query: 239 KVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIV 298 + + + EL+ R +P D+ +AE + + +D ++ + Sbjct: 181 HSANTFQQVVDYMLELVARKR-----VEPGDDILSELIAE-------KDGALSDADIAHL 228 Query: 299 VADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTA 358 + G TT + G LL++ +P + ++ ++ A Sbjct: 229 GNAVLLFGYETTIVRIDLGTLLLLRNPVQRAQLAEDPG------------------LAPA 270 Query: 359 VIHEVQRFG---DIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRF 415 + E+ R G + DI V I G ++ + + D+ + F Sbjct: 271 AVEEILRLGVGGKGSNALIPRYAHGDITVGETVIRTGDAVMLAIGAANYDDRAFPDGGLF 330 Query: 416 HPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS---FSVPTGQ 472 V+P + L F G R C+G LAR+EL F L + +VP Sbjct: 331 DLTR--------VRPRSHLAFGHGARHCIGRTLARIELTAVFERLFRRLPDLRLAVPEES 382 Query: 473 PR 474 R Sbjct: 383 LR 384 >3TKT-A nrPDB Length = 450 Score = 144 bits (362), Expect = 1e-34, Method: Composition-based stats. Identities = 66/296 (22%), Positives = 102/296 (34%), Gaps = 45/296 (15%) Query: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLT 256 D+P+ L L G E+ + L +P +AG V F++ F L Sbjct: 197 EDEPKMLFLTQQMFGGQDED--MNKSGLKDLPPEQISQIVAGAVAEFERYFAG----LAA 250 Query: 257 EHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAW 316 E R P D +A G P +D + SAG TTS + A Sbjct: 251 ERRRN------PTDDVATVIANAV-VDGEP---MSDRDTAGYYIITASAGHDTTSASSAG 300 Query: 317 GLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTH 376 L + PD+ RV+ + + ++ E R+ V Sbjct: 301 AALALARDPDLFARVKADRN------------------LLPGIVEEAIRWTTPVQ-HFMR 341 Query: 377 MTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPF 436 + D E+ G +I G L+ N + D A + +P +F P L F Sbjct: 342 TAATDTELCGQKIAAGDWLMLNYVAANHDPAQFPEPRKFDPTR---------PANRHLAF 392 Query: 437 SAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVF-AFLVSPSPYE 491 AG CLG LAR+E+ + LL G+P+ + F P ++ Sbjct: 393 GAGSHQCLGLHLARLEMRVLLDVLLDRVDSLELAGEPKRVNSTFVGGFKSLPMRWK 448 >3RWL-A nrPDB Length = 426 Score = 143 bits (361), Expect = 2e-34, Method: Composition-based stats. Identities = 61/350 (17%), Positives = 105/350 (30%), Gaps = 62/350 (17%) Query: 126 PAWREQRRFSVS--TLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVS 183 P EQR+ NL + ++ + V++ G P VS Sbjct: 117 PRHDEQRKAVSPIVAPANLAALEGTIRERVSK----------TLDGLPVGEEFDWVDRVS 166 Query: 184 NVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRF 243 I + F++ +L + G + E + Sbjct: 167 IEITTQMLATLFDFPFEERRKLTRWSDVTTAAPGGGVVE-------------SWDQRKTE 213 Query: 244 QKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLF 303 L E P DL LA + E V L Sbjct: 214 LLECAAYFQVLWNER----VNKDPGNDLIS-MLAHSPATRN-----MTPEEYLGNVLLLI 263 Query: 304 SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEV 363 G TT ++ G+L + +PD +++ V ++ E+ Sbjct: 264 VGGNDTTRNSMTGGVLALHKNPDQFAKLKANPALV------------------ETMVPEI 305 Query: 364 QRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDA 423 R+ + + D E+ G I KG ++ S +D+ V ++P F + Sbjct: 306 IRWQTPLA-HMRRTAIADSELGGKTIRKGDKVVMWYYSGNRDDEVIDRPEEFIIDR---- 360 Query: 424 QGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQP 473 +P L F G C+G LA M+L + + +L FS +P Sbjct: 361 ----PRPRQHLSFGFGIHRCVGNRLAEMQLRILWEEILTRFSRIEVMAEP 406 >5M0P-A nrPDB Length = 428 Score = 142 bits (357), Expect = 4e-34, Method: Composition-based stats. Identities = 76/448 (16%), Positives = 143/448 (31%), Gaps = 55/448 (12%) Query: 42 GLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQ-LAWTPVVVLNGLAAVREALVTHGEDTAD 100 GL N L V Q Y +Q R VF + L P VV+ G + + + Sbjct: 15 GLDNTLKVLKQGYLYTTNQRNRLNTSVFQTKALGGKPFVVVTGKEGAE--MFYNNDVVQR 72 Query: 101 RPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACL 160 +P + + +G G +++ +S + L L Sbjct: 73 EGMLP--KRIVNTLAGKGAIHTVDGKKHVDRKALFMSLMTEGNL----------NYVREL 120 Query: 161 CAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFL 220 + + + ++ +++ G R+ + E ++ + + Sbjct: 121 TRTLWHANTQRMESMDEVNIYRESIVLLTKVGTRWAG--------VQAPPEDIERIATDM 172 Query: 221 REVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEME 280 ++++ L ++ L+E + E R PP A E Sbjct: 173 DIMIDSFRALGGAFKGYKASKEARRRVEDWLEEQIIETRKG--NIHPPEGTALYEFAHWE 230 Query: 281 KAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIG 340 GNP S + A + +++GL M +P + +++ E D Sbjct: 231 DYLGNPMDSRTCAIDLMNTFRPLIA----INRFVSFGLHAMNENPITREKIKSEPD---- 282 Query: 341 QVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLS 400 Y EV+R+ VP + DI+ QG IP G L ++ Sbjct: 283 --------------YAYKFAQEVRRYYPFVPF-LPGKAKVDIDFQGVTIPAGVGLALDVY 327 Query: 401 SVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGR----RACLGEPLARMELFLF 456 DE++W+ P F PE F G P +P G C GE + + + Sbjct: 328 GTTHDESLWDDPNEFRPERFETWDG---SPFDLIPQGGGDYWTNHRCAGEWITVIIMEET 384 Query: 457 FTSLLQHFSFSVPTGQPRPSHHGVFAFL 484 + ++ VP + + ++ Sbjct: 385 MKYFAEKITYDVPEQDLEVDLNSIPGYV 412 >2FR7-A nrPDB Length = 412 Score = 141 bits (355), Expect = 7e-34, Method: Composition-based stats. Identities = 38/178 (21%), Positives = 65/178 (36%), Gaps = 28/178 (15%) Query: 286 PESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP 345 E ++V L SAG+ TT +A + + PD R++ + Sbjct: 232 DTGEITPEEAPLLVRSLLSAGLDTTVNGIAAAVYCLARFPDEFARLRADPS--------- 282 Query: 346 EMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKD 405 E RF V T+RD+E+ G I +G ++ L S +D Sbjct: 283 ---------LARNAFEEAVRFESPVQ-TFFRTTTRDVELAGATIGEGEKVLMFLGSANRD 332 Query: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQH 463 W+ P R+ K + F +G C+G+ +AR+E + +L + Sbjct: 333 PRRWDDPDRYDITR---------KTSGHVGFGSGVHMCVGQLVARLEGEVVLAALARK 381 >2X9P-A nrPDB Length = 404 Score = 141 bits (354), Expect = 1e-33, Method: Composition-based stats. Identities = 68/350 (19%), Positives = 103/350 (29%), Gaps = 70/350 (20%) Query: 122 ARYGPA-WREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDK 180 A G E RR ++ V E A L AF G P +G L Sbjct: 98 AESGRRQHAETRRLLTPLFS--ARRVLEMQPKVEEAADTLLDAFIA-QGPPGDLHGELT- 153 Query: 181 AVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKV 240 V +LT P+ L G+ + V Sbjct: 154 ----VPFALTVLCEVIGVPPQRRAELTTLLAGIAKLDDREGAV----------------- 192 Query: 241 LRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVA 300 R Q + L+ R A+P D+ + ++ + + Sbjct: 193 -RAQDDLFGYVAGLVEHKR-----AEPGPDIISRL----------NDGELTEDRVAHLAM 236 Query: 301 DLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVI 360 L AG+ + ++ + G++L+ HPD + + D + Sbjct: 237 GLLFAGLDSVASIMDNGVVLLAAHPDQRAAALADPD------------------VMARAV 278 Query: 361 HEVQRF-GDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEH 419 EV R + S D+E G I G ++ +L DE + P F Sbjct: 279 EEVLRTARAGGSVLPPRYASEDMEFGGVTIRAGDLVLFDLGLPNFDERAFTGPEEFDAAR 338 Query: 420 FLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVP 469 P L F G C+G PLAR+EL FT L P Sbjct: 339 ---------TPNPHLTFGHGIWHCIGAPLARLELRTMFTKLFTRLPELRP 379 >5FYF-A nrPDB Length = 470 Score = 140 bits (352), Expect = 2e-33, Method: Composition-based stats. Identities = 70/481 (14%), Positives = 140/481 (29%), Gaps = 90/481 (18%) Query: 19 LVDLMHRRQRWAARYPPGP----LPLPGLGNLLHVDFQNTPYCFDQLRRR---------- 64 L LM +++ P P P+P + N L ++ + F + + Sbjct: 32 LKFLMSAKRKTFGPRRPMPEFVETPIPDV-NTLALEDIDVSNPFLYRQGQWRAYFKRLRD 90 Query: 65 -----------FGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFG 113 FG +S+ + V + P + + Sbjct: 91 EAPVHYQKNSPFGPFWSVTRFEDILFVDKSHDL-----------FSAEPQIILGDPPE-- 137 Query: 114 PRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFR 173 S +F+A P QR + L K +E + + + PF Sbjct: 138 GLSVEMFIAMDPPKHDVQRSSVQGVVAPKNL--KEMEGLIRSRTGDVLDSLPTDK--PFN 193 Query: 174 PNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHI 233 + K ++ + + LLD E + + + A Sbjct: 194 WVPAVSKELTGRMLAT---------------LLDFPYEERHKLVEWSDRMAGAASATGGE 238 Query: 234 PALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPR-DLTEAFLAEMEKAKGNPESSFND 292 A + L + + P DL + E Sbjct: 239 FADENAMFDDAADMARSFSRLWRDKEARRAAGEEPGFDLISLLQSNKETKDLINRPM--- 295 Query: 293 ENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAH 352 + L G TT +++ GL+ M P +++ A Sbjct: 296 -EFIGNLTLLIVGGNDTTRNSMSGGLVAMNEFPREFEKLK------------------AK 336 Query: 353 MPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKP 412 ++ E+ R+ + + + +D+E+ G I KG ++ +S +DE ++ P Sbjct: 337 PELIPNMVSEIIRWQTPLAY-MRRIAKQDVELGGQTIKKGDRVVMWYASGNRDERKFDNP 395 Query: 413 FRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQ 472 +F + + F G C+G LA ++L + + +L+ F + Sbjct: 396 DQFIIDR--------KDARNHMSFGYGVHRCMGNRLAELQLRILWEEILKRFDNIEVVEE 447 Query: 473 P 473 P Sbjct: 448 P 448 >2XKR-A nrPDB Length = 398 Score = 139 bits (351), Expect = 2e-33, Method: Composition-based stats. Identities = 48/236 (20%), Positives = 80/236 (33%), Gaps = 37/236 (15%) Query: 263 DPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMI 322 A P DL ++ + +D+ L + + G TT TL+ G ++ Sbjct: 193 RRADPTDDLVSVLVSSEVDGE-----RLSDDELVMETLLILIGGDETTRHTLSGGTEQLL 247 Query: 323 LHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDI 382 + D +Q++ I E+ R+ V + + + D Sbjct: 248 RNRDQWDLLQRDPS------------------LLPGAIEEMLRWTAPVK-NMCRVLTADT 288 Query: 383 EVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRA 442 E G + G ++ S DEAV+ +P +F + P + L F G Sbjct: 289 EFHGTALCAGEKMMLLFESANFDEAVFCEPEKFDVQR---------NPNSHLAFGFGTHF 339 Query: 443 CLGEPLARMELFLFFTSLLQHFSF--SVPTGQPRPSHHGVFAFLVSPSPYELCAVP 496 CLG LAR+EL L +L+ V P F + P + P Sbjct: 340 CLGNQLARLELSLMTERVLRRLPDLRLVADDSVLPLRPANFVSGLESMP--VVFTP 393 >1F4U-A nrPDB Length = 368 Score = 139 bits (351), Expect = 2e-33, Method: Composition-based stats. Identities = 35/196 (17%), Positives = 70/196 (35%), Gaps = 30/196 (15%) Query: 287 ESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPE 346 S+ +D + L AG TT+ ++ ++ ++ +R+++E + Sbjct: 191 NSNLSDIEKLGYIILLLIAGNETTTNLISNSVIDFTRF-NLWQRIREENLYL-------- 241 Query: 347 MGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDE 406 I E R+ V + T +++ I +G + ++S +DE Sbjct: 242 -----------KAIEEALRYSPPV-MRTVRKTKERVKLGDQTIEEGEYVRVWIASANRDE 289 Query: 407 AVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSF 466 V+ +F P+ P L F +G CLG PLAR+E + + F Sbjct: 290 EVFHDGEKFIPDR---------NPNPHLSFGSGIHLCLGAPLARLEARIAIEEFSKRFRH 340 Query: 467 SVPTGQPRPSHHGVFA 482 + + + Sbjct: 341 IEILDTEKVPNEVLNG 356 >3A1L-A nrPDB Length = 425 Score = 139 bits (350), Expect = 3e-33, Method: Composition-based stats. Identities = 41/178 (23%), Positives = 65/178 (36%), Gaps = 28/178 (15%) Query: 285 NPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344 + S + + + L +AG TT+ LA +L + H DV ++ + Sbjct: 234 DTGSPLSVDGIVGTCVHLLTAGHETTTNFLAKAVLTLRAHRDVLDELRTTPES------- 286 Query: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404 T A + E+ R+ V VT DI + IP+G+ ++ L S + Sbjct: 287 -----------TPAAVEELMRYDPPVQ-AVTRWAYEDIRLGDHDIPRGSRVVALLGSANR 334 Query: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQ 462 D A + P E + F G CLG LAR E + +LL Sbjct: 335 DPARFPDPDVLDVHR---------AAERQVGFGLGIHYCLGATLARAEAEIGLRALLD 383 >4DO1-A nrPDB Length = 410 Score = 139 bits (349), Expect = 4e-33, Method: Composition-based stats. Identities = 77/439 (17%), Positives = 127/439 (28%), Gaps = 65/439 (14%) Query: 34 PPGPLPLPGLG-NLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALV 92 PP +P L + +DF + PY Q R G V + L V + A V L Sbjct: 13 PPNDSTIPHLAIDPFSLDFFDDPYPDQQTLRDAGPV--VYLDKWNVYGVARYAEVHAVLN 70 Query: 93 THGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQW 152 + R R + L PA R L Sbjct: 71 DPTTFCSSRGVGLSDFKKEKPWRPPSLILEADPPAHTRPRAVLSKVLS------------ 118 Query: 153 VTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEG 212 + FA + LL + + IA L Y F + L QEG Sbjct: 119 -PATMKTIRDGFAAAADAKVD--ELLQRGCIDAIADLA----EAYPLSVFPDAMGLKQEG 171 Query: 213 LKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLT 272 + + V NA ++ + + E P P Sbjct: 172 REHLLPYAGLVFNAF-------GPPNELRQTAIERSAPHQAYVNEQCQ--RPNLAPGGFG 222 Query: 273 EAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQ 332 + ++V L SAG+ TT + + + P +R++ Sbjct: 223 ACI------HAFTDTGEITPDEAPLLVRSLLSAGLDTTVNGIGAAVYCLARFPGELQRLR 276 Query: 333 QEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKG 392 + E RF V T+R++E+ G I +G Sbjct: 277 SDP------------------TLARNAFEEAVRFESPVQ-TFFRTTTREVELGGAVIGEG 317 Query: 393 TTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452 ++ L S +D W P + K + F +G C+G+ +AR+E Sbjct: 318 EKVLMFLGSANRDPRRWSDPDLYDITR---------KTSGHVGFGSGVHMCVGQLVARLE 368 Query: 453 LFLFFTSLLQHFSFSVPTG 471 + ++L + + G Sbjct: 369 GEVMLSALARKVAAIDIDG 387 >6HQW-A nrPDB Length = 445 Score = 138 bits (347), Expect = 6e-33, Method: Composition-based stats. Identities = 46/299 (15%), Positives = 95/299 (31%), Gaps = 35/299 (11%) Query: 167 HSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL-DLAQEGLKEESGFLREVLN 225 + + + ++V+ SL G RF++ D + L + R + Sbjct: 149 TPAKMVEMEAEIRRRTASVLDSLPWGERFDWVDKVSIELTTGMLAILFGFPWADRRLLTF 208 Query: 226 AVPVLLHIPA-LAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKG 284 + LA ++ + FL ++ A P DL + Sbjct: 209 WSDWAGDVELTLARELADTRFGFLGEMAHYFQRLWGARMQAPPSGDLISMMI------HS 262 Query: 285 NPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344 + + + + L G TT T++ + + PD + ++++ Sbjct: 263 EAMNHMSPQEFMGNLVLLIVGGNDTTRNTMSGIVHALDKFPDQRELLERDAS-------- 314 Query: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404 + E R+ + + + D E+ G +I G +I S + Sbjct: 315 ----------LIPNAVQECIRYVTPLA-HMRRTATADTELFGNQIKAGEKVILWYISANR 363 Query: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQH 463 DE V+E P + + L F G C+G LA ++L + + + Sbjct: 364 DETVFENPDKLMVDR--------PNARRHLSFGHGIHRCVGARLAELQLRILLEEMHER 414 >2UUQ-A nrPDB Length = 414 Score = 138 bits (347), Expect = 6e-33, Method: Composition-based stats. Identities = 57/342 (16%), Positives = 103/342 (30%), Gaps = 60/342 (17%) Query: 125 GPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSN 184 P E R+ + +++E V + + G L S Sbjct: 101 PPVHTEFRKLVSRGFTPRQV--ETVEPTVRKFVVERLEKLRANGGGDI-VTELFKPLPSM 157 Query: 185 VIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQ 244 V+A L + +E + G+ + ++ A V L Sbjct: 158 VVA----------------HYLGVPEEDWTQFDGWTQAIVAANAV----DGATTGALDAV 197 Query: 245 KAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFS 304 + + L+ R +P D +A A G+ + + + + + Sbjct: 198 GSMMAYFTGLIERRR-----TEPADDAISHLVAAGVGADGDTAGTLS---ILAFTFTMVT 249 Query: 305 AGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQ 364 G T + L + L+ PD +R + + + + + E+ Sbjct: 250 GGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGI------------------PDAVEELL 291 Query: 365 RFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVW-EKPFRFHPEHFLDA 423 R V G+ T+RD+ + IP G ++ S +DE + Sbjct: 292 RLTSPVQ-GLARTTTRDVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTR---- 346 Query: 424 QGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465 P L FS G CLG ARM+ + T LL Sbjct: 347 -----CPRNILTFSHGAHHCLGAAAARMQCRVALTELLARCP 383 >6GII-A nrPDB Length = 479 Score = 138 bits (347), Expect = 7e-33, Method: Composition-based stats. Identities = 71/438 (16%), Positives = 120/438 (27%), Gaps = 73/438 (16%) Query: 47 LHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPI 106 + P F + R +F V+ +++ + + Sbjct: 72 FQDAYMADPAQFVRWAREQVPIF--YAPKLNYWVVTRYDTIKQIF-RDPVTFSPSNVLQS 128 Query: 107 TQILGFGPRS----QGVFLARY-----GPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEA 157 R G R P E+RR + + + + E Sbjct: 129 FAQPSAEVRQVLERYGYAFNRTLVNEDEPMHLERRRVLMEPFAS---------EHLAEHE 179 Query: 158 ACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEY---DDPRFLRLLDLAQEGLK 214 + R V +I + + DD ++ A Sbjct: 180 PMVRELVRRAVNRFIDTGRAD--LVDQMIWEVPFTVALHFLGVDDDDREKMRRFA----- 232 Query: 215 EESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEA 274 + +NA P V F E+L + R T D R Sbjct: 233 -----IAHTVNAFG--RPSPEEQLAVAETVGQFWQFCGEVLEKMRRTADGPGWMR----- 280 Query: 275 FLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQE 334 + + D L ++ + A TT L ++ H V R + Sbjct: 281 ---YSIRQQKLYPDVVTDSYLHSMMQAIIVAAHETTVFATTNALKTLLEHETVWREI--- 334 Query: 335 IDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTT 394 D + +P A E R+ V G T+R++EV+G R+P G Sbjct: 335 ------------CADPSLIP---AAAEECLRYNGPVA-GWRRRTTREVEVEGVRLPVGAN 378 Query: 395 LITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELF 454 ++ ++S D A ++ P F L F G CLG L RME+ Sbjct: 379 ILMVVASANHDSAHFDDPEFFDIGR--------SNASEHLNFGYGAHQCLGRNLGRMEMQ 430 Query: 455 LFFTSLLQHFSFSVPTGQ 472 + L + Q Sbjct: 431 IMIEELSRRLPHMRLAEQ 448 >4PWV-A nrPDB Length = 446 Score = 135 bits (341), Expect = 3e-32, Method: Composition-based stats. Identities = 64/391 (16%), Positives = 115/391 (29%), Gaps = 62/391 (15%) Query: 90 ALVTHGEDTADRPPVPITQILGFGPRSQGVFLA-RYGPAWREQRRFSVSTLRNLGLGKKS 148 AL + + +L G + G LA G R R + + ++ Sbjct: 87 ALYKDNKKLTSEKGNVLVTLLAGGDSAAGKMLAVTDGAMHRGLRNVLLKSFS-----PQA 141 Query: 149 LEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208 L+ V + + R + D A + +++ D FL L+ Sbjct: 142 LKPIVDQI-RVNTTRLVVDAARRGECDFAADVAEQIPLNTISDLLGVPAADREFLLKLNK 200 Query: 209 AQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPP 268 + ++ A + L EL+ E R A+P Sbjct: 201 SALSSEDADQS-----------------ATDAWLARNEILLYFSELVAERR-----AKPT 238 Query: 269 RDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQ 328 D+ M K +E + + L G T+ ++ + +PD Sbjct: 239 EDVISVLANSMVDGK-----PLTEEVIVLNCYSLILGGDETSRLSMIDSVQTFTQYPDQW 293 Query: 329 RRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFR 388 ++ + EV R+ + D+E+ G Sbjct: 294 ELLRDGKVT------------------LESATEEVLRWATPA-MHFGRRAVTDMELHGQV 334 Query: 389 IPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPL 448 I G + +S +DE V+ P+ F P + F G CLG L Sbjct: 335 IAAGDVVTLWNNSANRDEEVFADPYAFDLNR---------SPNKHITFGYGPHFCLGAYL 385 Query: 449 ARMELFLFFTSLLQHFSFSVPTGQPRPSHHG 479 R E+ +L + + TG+P+ H Sbjct: 386 GRAEVHALLDALRTYTTGFEITGEPQRIHSN 416 >1UE8-A nrPDB Length = 367 Score = 135 bits (339), Expect = 5e-32, Method: Composition-based stats. Identities = 35/197 (17%), Positives = 68/197 (34%), Gaps = 31/197 (15%) Query: 286 PESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP 345 S+ ++ L AG TT+ + + L+ + V++ Sbjct: 191 ANSNLSELEKEGYFILLMIAGNETTTNLIGNAIEDFTLY-NSWDYVRE------------ 237 Query: 346 EMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKD 405 + E RF V + +T ++++ I +G + ++S +D Sbjct: 238 --------KGALKAVEEALRFSPPV-MRTIRVTKEKVKIRDQVIDEGELVRVWIASANRD 288 Query: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465 E V++ P F P+ P L F +G CLG PLAR+E + + F Sbjct: 289 EEVFKDPDSFIPDR---------TPNPHLSFGSGIHLCLGAPLARLEARIALEEFAKKFR 339 Query: 466 FSVPTGQPRPSHHGVFA 482 + + + + Sbjct: 340 VKEIVKKEKIDNEVLNG 356 >5HH3-A nrPDB Length = 397 Score = 134 bits (338), Expect = 7e-32, Method: Composition-based stats. Identities = 69/428 (16%), Positives = 120/428 (28%), Gaps = 90/428 (21%) Query: 74 AWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGV----FLARYGP-AW 128 + G +R+ L +D + R L +G + G+ FL +Y P Sbjct: 50 GGRTAWLATGYDEIRQVL--SSDDFSAR--------LLYGGTAAGITWPGFLTQYDPPEH 99 Query: 129 REQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIAS 188 RR + + + V A G P +V+ Sbjct: 100 TRLRRMVAPAFAVRRM--QKFQPQVERVVQDSLDAIEA-LGGPVDFVPRFGWSVATTATC 156 Query: 189 LTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFL 248 G DD L A + + F+ Sbjct: 157 DFLG--IPRDDQADLARSLHASRTERSG---------------------KRRTAAGNKFM 193 Query: 249 TQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMV 308 T ++++ R RD + + + G+ D L V A + AG Sbjct: 194 TYMNKMTARTR---------RDPGDDMFGVVVREYGD---EITDAELTGVAAFVMGAGAD 241 Query: 309 TTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGD 368 + LA G LM P+ ++++ D V + EV R+ Sbjct: 242 QVARFLAAGAWLMADDPEQFALLREKPDTV------------------PDWLDEVIRYLT 283 Query: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKP-FRFHPEHFLDAQGHF 427 + + D+ + I G T+ +L + + + +P RF Sbjct: 284 TDEKTHPRVATDDVRIGDHLIKAGDTVTCSLLAANR--RNFPRPEDRFDITRVRPE---- 337 Query: 428 VKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSP 487 L F G CLG LA + +L F R + P Sbjct: 338 -----HLAFGHGIHHCLGRSLAELVFRTAIPALAHRFPTLRLAEPHR-------EIRLGP 385 Query: 488 SPYELCAV 495 P+++ A+ Sbjct: 386 PPFDVEAL 393 >5DE9-A nrPDB Length = 410 Score = 134 bits (336), Expect = 1e-31, Method: Composition-based stats. Identities = 62/411 (15%), Positives = 115/411 (27%), Gaps = 75/411 (18%) Query: 79 VVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVST 138 +V N REA++ F P V P RR + Sbjct: 62 LVTNDPRFGREAVMDRQ---------VTRLAPHFRPARGAVGFLDP-PDHTRLRRSVAAA 111 Query: 139 LRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYD 198 G+ + V E + + + R P L + +S ++ C Sbjct: 112 FTARGV------ERVRERSRGMLDELVDAMLRAGPPADLTEAVLSPFPIAVIC------- 158 Query: 199 DPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEH 258 L+ + + + +L++ A R + +L+ Sbjct: 159 -----ELMGVPATDRHSMHTWTQLILSS-------SHGAEVSERAKNEMNAYFSDLI--- 203 Query: 259 RMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGL 318 D+T A + + L G + Sbjct: 204 --GLRSDSAGEDVTSLLGAAV------GRDEITLSEAVGLAVLLQIGG-EAVTNNSGQMF 254 Query: 319 LLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGD-IVPLGVTHM 377 L++ P++ R++ E + I E+ R+ +G++ + Sbjct: 255 HLLLSRPELAERLRSEPE------------------IRPRAIDELLRWIPHRNAVGLSRI 296 Query: 378 TSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFS 437 D+E++G RI G + + + +D V+ P R E P + F Sbjct: 297 ALEDVEIKGVRIRAGDAVYVSYLAANRDPEVFPDPDRIDFER---------SPNPHVSFG 347 Query: 438 AGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPS 488 G C G LAR+E L ++L P A + P Sbjct: 348 FGPHYCPGGMLARLESELLVDAVLDRVPGLKLAVAPEDVPFKKGALIRGPE 398 >2IJ7-A nrPDB Length = 396 Score = 132 bits (332), Expect = 3e-31, Method: Composition-based stats. Identities = 39/207 (18%), Positives = 77/207 (37%), Gaps = 30/207 (14%) Query: 270 DLTEAFLAEMEKAKGNPE-SSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQ 328 ++T + E+ + + +P S +DE + F AG+++T + L L+ +I P ++ Sbjct: 197 NITTGLMGELSRLRKDPAYSHVSDELFATIGVTFFGAGVISTGSFLTTALISLIQRPQLR 256 Query: 329 RRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFR 388 + ++ + A + E+ R G+ + + DI+V Sbjct: 257 NLLHEKPE------------------LIPAGVEELLRINLSFADGLPRLATADIQVGDVL 298 Query: 389 IPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPL 448 + KG ++ L D + P + P + L F G+ C G L Sbjct: 299 VRKGELVLVLLEGANFDPEHFPNPGSIELDR--------PNPTSHLAFGRGQHFCPGSAL 350 Query: 449 ARMELFLFFTSLLQHF---SFSVPTGQ 472 R + +LL+ +VP Q Sbjct: 351 GRRHAQIGIEALLKKMPGVDLAVPIDQ 377 >5HDI-A nrPDB Length = 404 Score = 129 bits (325), Expect = 2e-30, Method: Composition-based stats. Identities = 68/423 (16%), Positives = 130/423 (30%), Gaps = 76/423 (17%) Query: 53 NTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTA----------DRP 102 PY + R G V ++A + + G AV EA + ED + Sbjct: 17 QDPYPLYERMRAAGSVH--RIANSDFYAVCGWDAVNEA-IGRPEDFSSNLTATMTYTAEG 73 Query: 103 PVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCA 162 ++ G + + A PA R+ + L + +EQ+ + A Sbjct: 74 TAKPFEMDPLGGPTHVLATAD-DPAHAVHRKLVLRHLA--AKRIRVMEQFTVQAAD---- 126 Query: 163 AFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFL-- 220 A++N + + DP +L+ + G + Sbjct: 127 --RLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEGLVEN 184 Query: 221 REVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEME 280 +++ A L+ + + A D + L E+ Sbjct: 185 DQLVAAGVALMELSGYIFEQFDRAAA-----------------------DPRDNLLGEL- 220 Query: 281 KAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIG 340 A + ++++ LF+AG +T+ L + ++ PD+Q++V+ + Sbjct: 221 -ATACASGELDTLTAQVMMVTLFAAGGESTAALLGSAVWILATRPDIQQQVRANPE---- 275 Query: 341 QVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLS 400 A I E R+ G + G +P + L+ Sbjct: 276 --------------LLGAFIEETLRYEPPFR-GHYRHVRNATTLDGTELPADSHLLLLWG 320 Query: 401 SVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSL 460 + +D A +E P F + + F G C+G LAR+E + L Sbjct: 321 AANRDPAQFEAPGEFRLDRAGGK--------GHISFGKGAHFCVGAALARLEARIVLRLL 372 Query: 461 LQH 463 L Sbjct: 373 LDR 375 >6FYJ-A nrPDB Length = 421 Score = 129 bits (324), Expect = 3e-30, Method: Composition-based stats. Identities = 62/423 (14%), Positives = 127/423 (30%), Gaps = 58/423 (13%) Query: 67 DVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGP 126 D+F +L + + G A E E + P + + A G Sbjct: 39 DIFETRLLGKKAICMGGKEAA-EIFYD-TEKFKRKDAAP--NRVVQTLFGKNGVQALDGQ 94 Query: 127 AWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVI 186 + ++ +S + LE+ A +L + ++ Sbjct: 95 THKHRKEMFMSIMS-----PDELEKLTDITKKQW--EIAVDKWEQMD-KVILYEEAKEIM 146 Query: 187 ASLTCGRR-FEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQK 245 C + RL + + + + G+ R + Sbjct: 147 CRTACQWAGVPVQENEVKRLTKNLGAMFESAAA------------VGLKHWLGRHARNYE 194 Query: 246 AFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSA 305 ++EL+ R PP + T + +GN + I + A Sbjct: 195 EI--WIEELIDRVRDG--KVNPPENTTLHKFSWYRDLEGNLLDTETAAVEVINILRPIVA 250 Query: 306 GMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQR 365 + + + L + +P+ + +++ Y+ + EV+R Sbjct: 251 ----IAIFINFIALALHHYPEEKEKLKS-----------------GDKKYSQMFVQEVRR 289 Query: 366 FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQG 425 F P V + +D +G++ +GT + +L D +W+ P F P+ F +G Sbjct: 290 FYPFFPFVVA-LVKKDFTWKGYKFEEGTLTLLDLYGTNHDPEIWKNPDVFSPDRFAKWEG 348 Query: 426 HFVKPEAFLPFSAGR----RACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVF 481 P +F+P G C GE + + + L + VP S + Sbjct: 349 ---SPFSFIPQGGGDYFMGHRCAGEWVTIEVMKVSLDYLTNRMDYEVPDQDLSFSMASMP 405 Query: 482 AFL 484 + Sbjct: 406 SIP 408 >5H1Z-A nrPDB Length = 407 Score = 128 bits (322), Expect = 6e-30, Method: Composition-based stats. Identities = 46/284 (16%), Positives = 92/284 (32%), Gaps = 48/284 (16%) Query: 226 AVPVLLHIPALAGKVLRFQKAFLTQLD-----ELLTEHRM----------TWDPAQPPRD 270 + +L P + L F + ++ EL E A+ + Sbjct: 153 MLAILFDFPWEERRKLTFWSDWAGDIELVKNEELRLERLRHMYECGGYFQNLWNAKIGKP 212 Query: 271 LTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRR 330 T ++ M + + + + + L G TT T++ + L PD + + Sbjct: 213 PTPDLISMMIHS--DAMAEMDQMEFLGNLILLIVGGNDTTRNTMSAVAYGLDLFPDQRAK 270 Query: 331 VQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIP 390 ++ + + + E+ R+ + + + D E++G +I Sbjct: 271 LEADPSMI------------------PNTVQEIIRWQTPLA-HMRRTATVDSELEGQQIK 311 Query: 391 KGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLAR 450 G L S +DE+V+E R + L F G C+G LA Sbjct: 312 AGDKLALWYISANRDESVFENADRIIVDR--------PNARRHLAFGHGIHRCVGARLAE 363 Query: 451 MELFLFFTSLL-QHFSFSVPTGQPRPSH---HGVFAFLVSPSPY 490 +++ + + + +V R + HG V S Y Sbjct: 364 LQIAVLLEEMAKRRMRVNVLGEPERVAACFVHGYRKLPVEISRY 407 >6DCD-A nrPDB Length = 424 Score = 128 bits (321), Expect = 6e-30, Method: Composition-based stats. Identities = 41/203 (20%), Positives = 71/203 (34%), Gaps = 30/203 (14%) Query: 262 WDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLM 321 D + PR+ LA G+ + + LF+AG TT+ L + ++ Sbjct: 212 EDRRRQPRNDVLTALATATYPDGSTPEVID---VVRSATFLFAAGQETTAKLLTAAMRVL 268 Query: 322 ILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRD 381 PD+QRR+++ + I E R V + + + Sbjct: 269 GDRPDIQRRLRE------------------NRSLIPNFIEESLRMDSPVK-SDSRLARKR 309 Query: 382 IEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRR 441 V G I GT ++ + +D +E P F + + F+ G Sbjct: 310 TTVGGLDIAAGTVVMVLPGAANRDPRRFEDPHEFRLDR--------PNVREHMAFARGVH 361 Query: 442 ACLGEPLARMELFLFFTSLLQHF 464 +C G PLAR+E + +L Sbjct: 362 SCPGGPLARVEGRVSLERILDRM 384 >3OO3-A nrPDB Length = 384 Score = 127 bits (318), Expect = 1e-29, Method: Composition-based stats. Identities = 59/319 (18%), Positives = 107/319 (33%), Gaps = 62/319 (19%) Query: 193 RRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAV-PVLLHIPALAGKVLRFQKAFLTQL 251 RR E PR +++ + + + V +A P+ +I V R +A +L Sbjct: 101 RRMERLRPRIEEIVEECLDDFESVGAPVDFVRHAAWPIPAYIACEFLGVPRDDQA---EL 157 Query: 252 DELLTEHRMTWDPAQ------------------PPRDLTEAFLAEMEKAKGNPESSFNDE 293 ++ E R + P Q RD + + + + G + +DE Sbjct: 158 SRMIRESRESRLPRQRTLSGLGIVNYTKRLTSGKRRDPGDGMIGVIVREHG---AEISDE 214 Query: 294 NLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHM 353 L + + LA +LL++ HPD ++++ + Sbjct: 215 ELAGLAEGNLIMAAEQMAAQLAVAVLLLVTHPDQMALLREKPE----------------- 257 Query: 354 PYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPF 413 + EV R IV + D+ + G I G L ++ + + Sbjct: 258 -LIDSATEEVLRHASIVEAPAPRVALADVRMAGRDIHAGDVLTCSMLATNRAPG-----D 311 Query: 414 RFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS---FSVPT 470 RF + + F G C+G PLAR++L + +++ F +VP Sbjct: 312 RFDITR---------EKATHMAFGHGIHHCIGAPLARLQLRVALPAVVGRFPSLRLAVPE 362 Query: 471 GQPR--PSHHGVFAFLVSP 487 R P FA P Sbjct: 363 EDLRFKPGRPAPFAVEELP 381 >6G5O-A nrPDB Length = 399 Score = 127 bits (318), Expect = 2e-29, Method: Composition-based stats. Identities = 40/250 (16%), Positives = 79/250 (31%), Gaps = 35/250 (14%) Query: 248 LTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGM 307 L + E ++ P D+ L + + E ++ V+ F+ G Sbjct: 169 ANILYHYIDE-QIDRASENPGDDMYSVLLNSEFEGR-----KLTKEEVKGVMVLTFAGGR 222 Query: 308 VTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFG 367 T + + + HP+ R+++E + T + E+ R+ Sbjct: 223 DTVINAVTNSIAYLAEHPEALERLRKEPE------------------ITGRAVEEMIRYF 264 Query: 368 DIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHF 427 + + + + D V + + + +S +D AV+E P + Sbjct: 265 SPL-TQMGRVVTEDTHVCEHAVKADSRISLCWASANRDAAVFENPNEIVLDR-------- 315 Query: 428 VKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF-SFSVPTGQPRPSHHGVFAFLVS 486 K + F CLG AR L + +L Q SF + + F V Sbjct: 316 -KVNPHVGFGFSHHNCLGATHARQILKILLQTLAQKVASFEILDYKENIEDLDHFQRKVG 374 Query: 487 PSPYELCAVP 496 ++ P Sbjct: 375 FHNIQIKFNP 384 >1WIY-A nrPDB Length = 389 Score = 124 bits (312), Expect = 8e-29, Method: Composition-based stats. Identities = 51/212 (24%), Positives = 74/212 (34%), Gaps = 29/212 (13%) Query: 286 PESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP 345 P S E L AG T ++ L W LL+ PD Q+RV Sbjct: 202 PLSHLPRERALSEAVTLLVAGHETVASALTWSFLLLSHRPDWQKRV-------------- 247 Query: 346 EMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKD 405 A E R + +T R + + R+P+GTTL+ + + Sbjct: 248 ----AESEEAALAAFQEALRLYPPAWI-LTRRLERPLLLGEDRLPQGTTLVLSPYVTQR- 301 Query: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465 + + F PE FL +G + PF G+R CLG A +E + + + F Sbjct: 302 -LYFPEGEAFQPERFLAERG--TPSGRYFPFGLGQRLCLGRDFALLEGPIVLRAFFRRFR 358 Query: 466 FSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR 497 P P V A + L A PR Sbjct: 359 L-----DPLP-FPRVLAQVTLRPEGGLPARPR 384 >5D3U-A nrPDB Length = 427 Score = 123 bits (308), Expect = 2e-28, Method: Composition-based stats. Identities = 58/270 (21%), Positives = 89/270 (32%), Gaps = 35/270 (12%) Query: 204 RLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWD 263 + +E L + ++ P +L T ELL R Sbjct: 174 HAFGVPEEDLGFLIPRVNTIMTYFSGPKDQPVTQEIILEKLTDLHTYASELLQGMRGKVL 233 Query: 264 PAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMIL 323 P D A LA + L +V LF+ TT +L+ G L Sbjct: 234 P-----DTVIARLAAAQDGLTETTPEQTVHQLALVFIALFAP---TTPGSLSSGTLAFAR 285 Query: 324 HPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIE 383 +P R + V +EV R+ + ++D+E Sbjct: 286 NPRQVERFLADQACV------------------DNTANEVLRYNASNQFTW-RVAAKDVE 326 Query: 384 VQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRAC 443 + G RI G TL L S +D ++E+P F + A+ L F G AC Sbjct: 327 MGGVRIEAGQTLALFLGSANRDANMFERPNDFDLDRPNSAR--------HLSFGQGVHAC 378 Query: 444 LGEPLARMELFLFFTSLLQHFSFSVPTGQP 473 L L ++L F+ +LL F G+P Sbjct: 379 LAAQLISLQLKWFYVALLNRFPGIRTAGEP 408 >6G71-A nrPDB Length = 405 Score = 122 bits (307), Expect = 2e-28, Method: Composition-based stats. Identities = 49/281 (17%), Positives = 85/281 (30%), Gaps = 41/281 (14%) Query: 200 PRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHR 259 L+ + + + +++ P + K + L+E++ H Sbjct: 143 ENLRALIGFENASEADLQRWSQTLIDGAGNYPDDPDVWAKAKQSSDEIDAALEEMIQWH- 201 Query: 260 MTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLL 319 +P L L + E++R + G+ L L Sbjct: 202 ----SGRPGDSLLSYLLRSADY-------QMPLESIRSNIKMTIGGGLNEPRDVLGVSTL 250 Query: 320 LMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTS 379 ++ V ++ AV E R+ + + V T Sbjct: 251 ALLSSSKQLELVLRDP------------------KLWGAVFEESIRWVAPIGM-VPRQTV 291 Query: 380 RDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAG 439 D E+ G+ IP+G L + S +D +VW P RF E EA L F G Sbjct: 292 VDTELDGYFIPRGAKLGLCILSANRDRSVWSDPDRFDIER---------GSEAHLAFGKG 342 Query: 440 RRACLGEPLARMELF-LFFTSLLQHFSFSVPTGQPRPSHHG 479 CLG AR ++ + +L +H G Sbjct: 343 VHVCLGAWAARSQVADVGLPALFSRLKGLRLDPNQEATHGG 383 >5EX8-A nrPDB Length = 424 Score = 121 bits (304), Expect = 5e-28, Method: Composition-based stats. Identities = 61/419 (14%), Positives = 118/419 (28%), Gaps = 88/419 (21%) Query: 82 NGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGV----FLARY-GPAWREQRRFSV 136 G+ VR+ L + + R L +G + G+ FL +Y P RR V Sbjct: 85 TGIDEVRQVL--GSDKFSAR--------LLYGGTAAGITWPGFLTQYDPPEHTRLRRMVV 134 Query: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196 + + + V + G P A++ G Sbjct: 135 PAFSHRRM--QKFRPRVEQIVQDSLDTI-ESLGGPVDFVPHFGWAIATPATCDFLG--IP 189 Query: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLT 256 DD L + LA + + + F+T + + + Sbjct: 190 RDDQADLARILLASRTDRSD---------------------KRRTAAGNKFMTYMKQHVA 228 Query: 257 EHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAW 316 + R + + + G+ D L V A + A + LA Sbjct: 229 QSRRGS---------GDDLFGIVGRENGDA---ITDAELTGVAAFVMGAAADQVARLLAA 276 Query: 317 GLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTH 376 G LM+ P ++++ + V + E R+ Sbjct: 277 GAWLMVEQPAQFALLREKPETV------------------PEWLDETMRYLTTDEKTHPR 318 Query: 377 MTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPF 436 + ++D+ + + G T+ +L + + F + L F Sbjct: 319 VATQDVRIGNQLVKAGDTVTCSLLAANR-PNYPSAEDEFDITR---------EKAEHLAF 368 Query: 437 SAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAV 495 G CLG +A + + +L F R + P P+++ A+ Sbjct: 369 GHGIHHCLGRAMAELMFKVSIPALAHRFPTLRLADPQR-------EITLGPPPFDVEAL 420 >3OFT-A nrPDB Length = 396 Score = 121 bits (304), Expect = 6e-28, Method: Composition-based stats. Identities = 72/375 (19%), Positives = 119/375 (31%), Gaps = 65/375 (17%) Query: 109 ILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHS 168 G G Q + L + G + R + L + + +LE V A L + Sbjct: 75 TPGLGKVMQFIPLQQDGAEHKAFRTPVMKGLASRFVV--ALEPKVQAVARKLMESLRP-R 131 Query: 169 GRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVP 228 G + + N+ FL L+D+ E R L + Sbjct: 132 GSCDFVSDFAEILPLNI----------------FLTLIDVPLED--------RPRLRQLG 167 Query: 229 VLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPES 288 V L P + V + ++A L + + AQP DL L+E + Sbjct: 168 VQLTRPDGSMTVEQLKQAADDYLWPFIEKR-----MAQPGDDLFSRILSEPVGGR----- 217 Query: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG 348 + + R + +L G+ T + + L + HP+ QR +++ D Sbjct: 218 PWTVDEARRMCRNLLFGGLDTVAAMIGMVALHLARHPEDQRLLRERPD------------ 265 Query: 349 DQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAV 408 A E+ R V V+ D++ G I KG + D A Sbjct: 266 ------LIPAAADELMRRYPTV--AVSRNAVADVDADGVTIRKGDLVYLPSVLHNLDPAS 317 Query: 409 WEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS-FS 467 +E P + L P G C+G LARME+ +F L F+ Sbjct: 318 FEAPEEVRFDRGL-------APIRHTTMGVGAHRCVGAGLARMEVIVFLREWLGGMPEFA 370 Query: 468 VPTGQPRPSHHGVFA 482 + + G Sbjct: 371 LAPDKAVTMKGGNVG 385 >2WIY-A nrPDB Length = 394 Score = 121 bits (304), Expect = 6e-28, Method: Composition-based stats. Identities = 38/242 (15%), Positives = 74/242 (30%), Gaps = 33/242 (13%) Query: 236 LAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENL 295 A + L + E P L ++ L + Sbjct: 171 PADGDVDRAAVAFGYLSARVAEMLED-KRVNPGDGLADSLLDAARA------GEITESEA 223 Query: 296 RIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPY 355 + ++ G + +A G+ L P+V + + Sbjct: 224 IATILVFYAVGHMAIGYLIASGIELFARRPEVFTAFRNDESA------------------ 265 Query: 356 TTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRF 415 A+I+E+ R L + D+E+ G I G+ + + + +D V++ P F Sbjct: 266 RAAIINEMVRMDPP-QLSFLRFPTEDVEIGGVLIEAGSPIRFMIGAANRDPEVFDDPDVF 324 Query: 416 HPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRP 475 A + L F G +C G+ ++R E F L + + +P Sbjct: 325 DHTRPPAASRN-------LSFGLGPHSCAGQIISRAEATTVFAVLAERYERIELAEEPTV 377 Query: 476 SH 477 +H Sbjct: 378 AH 379 >6HQD-A nrPDB Length = 420 Score = 120 bits (301), Expect = 1e-27, Method: Composition-based stats. Identities = 62/427 (14%), Positives = 127/427 (29%), Gaps = 72/427 (16%) Query: 51 FQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQIL 110 + P + + +G +S+ V + + T + Sbjct: 42 RREDPVHYCKASE-YGPYWSITKFSDIVAIDTNHKVFS------SDHTNG---SFVLDDT 91 Query: 111 GFGPRSQGVFLARY----GPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFAN 166 G++L + P R + L + E + E + + Sbjct: 92 TLNAVDGGIYLPNFLGMDPPKHDVHRMVVSPIVAPQNLLR--FEATIRERTKRVLSELPI 149 Query: 167 HSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNA 226 + ++ + L +DD R L +++ Sbjct: 150 GEEFNWVDRVSIELTTMMLATLLDF----PFDDRRKL--------------TRWSDIITT 191 Query: 227 VPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNP 286 P + + L L E + A PP+ + LA + Sbjct: 192 RPG-YGLVDSWEQRESELMECLAYFQRLYAERQ-----AMPPKPDLISMLAHSPE----- 240 Query: 287 ESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPE 346 + +A L G TT ++++ + L+P +V+ Sbjct: 241 MQDLTPTDFLGTLALLIVGGNDTTRSSMSGSAMACHLYPQEFDKVR-------------- 286 Query: 347 MGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDE 406 + +VI EV R+ + + D+E +G +I KG ++ S +D+ Sbjct: 287 ----NNRALLASVIPEVVRWQTPIA-HMRRTALEDVEFRGKQIRKGDKVVMWYLSGNRDD 341 Query: 407 AVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSF 466 V ++P F + + L F G CLG LA ++L + + + + +S Sbjct: 342 EVIDRPMDFIADR--------PRARHHLSFGFGIHRCLGNRLAELQLKILWEEMCERYSR 393 Query: 467 SVPTGQP 473 G+P Sbjct: 394 IEVCGEP 400 >6BLD-A nrPDB Length = 419 Score = 118 bits (296), Expect = 5e-27, Method: Composition-based stats. Identities = 58/346 (16%), Positives = 96/346 (27%), Gaps = 53/346 (15%) Query: 120 FLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLD 179 FLA P + R+ + + + +E + A + G Sbjct: 102 FLAMDPPRHTKLRKLVSAAFTPRQVRR--IEDSIKINAKGIVDELRMAGGG-----VDFV 154 Query: 180 KAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGK 239 + + + T + R+ A + + VL + Sbjct: 155 EHCAKELPIRTLSDMVGIPEADRERVAHAADALVSWADPRYLNGREPLAVLFENQMYLHQ 214 Query: 240 VLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVV 299 V A E R +P DL A + D ++ Sbjct: 215 VAASLAA----------ERR-----DRPGDDLFSALVNAEVDGD-----RLADADVAAFF 254 Query: 300 ADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAV 359 L AG TT T++ GL + P + + + D IG Sbjct: 255 VLLAVAGNDTTRQTISHGLKALTDFPSQKAWLLADFDTRIG-----------------TA 297 Query: 360 IHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEH 419 + E+ R+ V + + D E+ G I G ++ +S DE + P R Sbjct: 298 VEELVRWATPV-MTFRRTAAADFELGGQLIRAGEKVVMFYASGNWDEDAFCHPERLDLSR 356 Query: 420 FLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465 + F CLG LAR +L F LL Sbjct: 357 SPNPHVGFGGGGVH--------FCLGAHLARAQLRAIFGELLVQLP 394 >4FB2-A nrPDB Length = 398 Score = 117 bits (292), Expect = 1e-26, Method: Composition-based stats. Identities = 54/387 (13%), Positives = 109/387 (28%), Gaps = 72/387 (18%) Query: 80 VLNGLAAVREALVTHGEDTADRP-PVPITQILGFGPRSQGVFLARYGPAWREQRRFSVST 138 V+ G + +A++ + + +++ P + F G + P ++ R+ Sbjct: 48 VVAGYKEI-QAVIQNTKAFSNKGVTFPRYETGEFELMMAG----QDDPVHKKYRQLVAKP 102 Query: 139 LRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYD 198 E + L + G + Sbjct: 103 FS-------------PEATDLFTEQLRQSTNDLIDARIELGE-----------GDAATWL 138 Query: 199 DPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEH 258 L GL E G V + H+ + + L+ E Sbjct: 139 ANEIPARLTAILLGLPPEDG--DTYRRWVWAITHVENP-EEGAEIFAELVAHARTLIAER 195 Query: 259 RMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGL 318 R P D+ + + S ++++L L G+ T+ L+ Sbjct: 196 R-----TNPGNDIMSRVIMSKIDGE-----SLSEDDLIGFFTILLLGGIDNTARFLSSVF 245 Query: 319 LLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMT 378 + +++RR+ AH + E+ RF +G + Sbjct: 246 WRLAWDIELRRRL------------------IAHPELIPNAVDELLRFYGPAMVG--RLV 285 Query: 379 SRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSA 438 ++++ V + G T + +D + ++ P E P L Sbjct: 286 TQEVTVGDITMKPGQTAMLWFPIASRDRSAFDSPDNIVIER---------TPNRHLSLGH 336 Query: 439 GRRACLGEPLARMELFLFFTSLLQHFS 465 G CLG L R+E + T L+ Sbjct: 337 GIHRCLGAHLIRVEARVAITEFLKRIP 363 >3WEC-A nrPDB Length = 419 Score = 117 bits (292), Expect = 1e-26, Method: Composition-based stats. Identities = 62/400 (15%), Positives = 102/400 (25%), Gaps = 65/400 (16%) Query: 81 LNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLR 140 L G H +P LG ++ L R R Sbjct: 63 LFGKDFANSTFFDHLTSMMGE-DMPPFLGLGIDGDARPFMLTDPPEHTR-LRGLVSDAFT 120 Query: 141 NLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDP 200 S++ V A+ + + V + I + R + Sbjct: 121 R--STTTSMDDIVLSAASSAVRHLEHCTDAVSEVAEPFPVEVLSSILGIPDKDRGRF--- 175 Query: 201 RFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRM 260 S + V + + IP ++E + R Sbjct: 176 ----------------SEWSNLVAGVLDINFAIP------KEVADRRSAAIEESIDYFRT 213 Query: 261 TWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLL 320 P L + + + + + AG TTS T+ L+ Sbjct: 214 LATSGNAPEGLVRRL-----SEVSHGGDQLSVDEIAATCLLITVAGQETTSNTIGNMLIT 268 Query: 321 MILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSR 380 H D +V+ + + EV RF + Sbjct: 269 FSRHADQFEQVRANPQ------------------FIENAVAEVLRFEPPAHEA-GRIALE 309 Query: 381 DIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGR 440 D EV G I KG ++ L+S + E+ F + L + G Sbjct: 310 DCEVSGANITKGDAVMVLLASGNR--EAVERGDTFSVTR---------PDVSSLSYGRGI 358 Query: 441 RACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGV 480 CLG LA L F L Q + S+ +P G+ Sbjct: 359 HHCLGSALANSMLQHFLRELSQRYR-SIEVAEPINYKPGM 397 >5YHJ-A nrPDB Length = 413 Score = 116 bits (290), Expect = 2e-26, Method: Composition-based stats. Identities = 70/449 (15%), Positives = 141/449 (31%), Gaps = 67/449 (14%) Query: 48 HVDFQNTPYCF-DQLRRRF-GDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVP 105 VDF Y F R+ F ++F +L V+ L G A E + T R Sbjct: 14 SVDFLREGYLFVANRRKSFQSNIFESRLLGERVICLGGEEAA-EVFYDANKFT--RQDAA 70 Query: 106 ITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFA 165 ++L GV R+ +L + K+++++ + Sbjct: 71 PKRLLKTLFGEGGVQTLDGSEH--THRKQMFMSL----MTKENIDRLLRLTYREWNQIER 124 Query: 166 NHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLN 225 G + + ++ ++ + + + + + L Sbjct: 125 --MGEEIVLYDIAQEV---LMKAVCEWSGVPLAKEEVGKRTEEMRLLFESGTSLGPTYL- 178 Query: 226 AVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGN 285 + + + + + +++ E R L E + Sbjct: 179 -------------QGRKARSSAEVWIRQMVKEVRSNRLLPNEH-----TALYEFSWHRDE 220 Query: 286 PESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRV-QQEIDDVIGQVRR 344 +E + + V ++ + + L + +L + PDV+ +V + E+ Sbjct: 221 SGELLPEEVVAVEVLNILRPTVAISVYVL-FTVLALHQFPDVKEQVERGEVSK------- 272 Query: 345 PEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLK 404 T + EV+RF P+ D E G+ P+GT + +L Sbjct: 273 ------------TEFVQEVRRFYPFFPVAAAR-VKTDFEWDGYAFPEGTLTLLDLYGTNH 319 Query: 405 DEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGR----RACLGEPLARMELFLFFTSL 460 D ++W +P RF P F D + P F+P G C GE + L Sbjct: 320 DVSIWTEPDRFDPSRFKDWKE---SPFNFIPQGGGDVDFGHRCAGEHVTIAILAQVIELF 376 Query: 461 LQHFSFSVPTGQPRPSHHGVFAFLVSPSP 489 + ++++VP P+ + P Sbjct: 377 TKEYAYTVP---PQDLSYSFVDMPSLPKS 402 >2NZA-A nrPDB Length = 413 Score = 114 bits (285), Expect = 9e-26, Method: Composition-based stats. Identities = 34/190 (17%), Positives = 63/190 (33%), Gaps = 32/190 (16%) Query: 287 ESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPE 346 + + L G + + L L++ ++ R+++ Sbjct: 227 RGEVGETEAVGLAGPLQIGG-EAVTHNVGQMLYLLLTRRELMARMRERPGA--------- 276 Query: 347 MGDQAHMPYTTAVIHEVQRFGD-IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKD 405 + E+ R+ +G+ + D+EV G RI G + + + +D Sbjct: 277 ---------RGTALDELLRWISHRTSVGLARIALEDVEVHGTRIAAGEPVYVSYLAANRD 327 Query: 406 EAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465 V+ P R + P L + G C G LARM+ L +LL+ Sbjct: 328 PDVFPDPDRIDLDR---------DPNPHLAYGNGHHFCTGAVLARMQTELLVDTLLERLP 378 Query: 466 ---FSVPTGQ 472 +VP Q Sbjct: 379 GLRLAVPAEQ 388 >3BUJ-A nrPDB Length = 397 Score = 111 bits (278), Expect = 6e-25, Method: Composition-based stats. Identities = 38/216 (17%), Positives = 69/216 (31%), Gaps = 36/216 (16%) Query: 237 AGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLR 296 A + R A D + DL L ++ + + Sbjct: 173 AEDMRRGHAAIAEFADYVERALARRRREG--GEDLLALMLDAHDR------GLMSRNEIV 224 Query: 297 IVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYT 356 V G T ++ + +L ++ HPD +++ D Sbjct: 225 STVVTFIFTGHETVASQVGNAVLSLLAHPDQLDLLRRRPD------------------LL 266 Query: 357 TAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFH 416 + E R+ V T D+E++G R+ + ++ + +D +++P F Sbjct: 267 AQAVEECLRYDPSVQ-SNTRQLDVDVELRGRRLRRDDVVVVLAGAANRDPRRYDRPDDFD 325 Query: 417 PEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452 E P + F AG R CLG LAR + Sbjct: 326 IER---------DPVPSMSFGAGMRYCLGSYLARTQ 352 >5OMS-A nrPDB Length = 409 Score = 110 bits (275), Expect = 1e-24, Method: Composition-based stats. Identities = 50/372 (13%), Positives = 105/372 (28%), Gaps = 48/372 (12%) Query: 95 GEDTADRPPVPITQILGFGPR-SQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWV 153 + A P G + G + R L+ + ++ V Sbjct: 56 CREVATSPDFEAVITPAGGRTFGHPAIIGVNGDIHADLRSMVEPALQ-PAEVDRWIDDLV 114 Query: 154 TEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGL 213 A F N + L ++ + G + +L + Sbjct: 115 RPIARRYLERFEN------DGHAELVAQYCEPVSVRSLGDLLGLQEVDSDKLREWFA--- 165 Query: 214 KEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTE 273 K F ++ + P + + + +D L+ + + P D Sbjct: 166 KLNRSFTNAAVDENGEFAN-PEGFAEGDQAKAEIRAVVDPLIDK------WIEHPDD--- 215 Query: 274 AFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQ 333 + ++ P + + E + + M +A L+ + P+ V Sbjct: 216 SAISHWLHDGMPPGQTRDREYIYPTIYVYLLGAMQEPGHGMASTLVGLFSRPEQLEEV-- 273 Query: 334 EIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGT 393 + D +P I E R+ + ++++ + + G +P GT Sbjct: 274 -------------VDDPTLIP---RAIAEGLRWTSPIWSATARISTKPVTIAGVDLPAGT 317 Query: 394 TLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMEL 453 ++ + S D +E P ++ P L F AG AC G A + Sbjct: 318 PVMLSYGSANHDTGKYEAPSQYDLHR---------PPLPHLAFGAGNHACAGIYFANHVM 368 Query: 454 FLFFTSLLQHFS 465 + L + Sbjct: 369 RIALEELFEAIP 380 >5KYO-A nrPDB Length = 430 Score = 108 bits (270), Expect = 5e-24, Method: Composition-based stats. Identities = 61/404 (15%), Positives = 115/404 (28%), Gaps = 51/404 (12%) Query: 91 LVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLE 150 + + P P+ G + + RFS T+ Sbjct: 59 FHQSWREIMRQAPHPLMWTPHNGGHWVALRSDLAETVMSDFERFSNHTVLVPKETAGEAY 118 Query: 151 QWVTEEAACLCAA-FANHSGRPFRPNGL--LDKAVSNVIASLTCGRRFEYDDPRFLRLLD 207 + + F + P L +++ V+++ SL G R + + Sbjct: 119 RLIPLSLDPPEHRPFRSLLNENLGPKPLRPIEQVVTDLAVSLIEGFRPKGRCNFTHEFAE 178 Query: 208 LAQEGLKEESGFLREVLNAVPVLLHI------PALAGKVLRFQKAFLTQLDELLTEHRMT 261 Q ++ + + +P L H+ P + + K F L ++ R Sbjct: 179 --QLPVRIFMRIVDLPVEDLPKLKHLADQYTRPDGSIPLDDVTKQFREYLRPVIEARR-- 234 Query: 262 WDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLM 321 +P D+ + + D + + G+ T L + + Sbjct: 235 ---IKPGEDMISRMINGEVGGR-----PLTDIEAENICIQVLVGGLDTVVNMLGFTFSHL 286 Query: 322 ILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRD 381 ++R + + P + D A + E R +V RD Sbjct: 287 AKDHALRRAIAAD----------PSLIDDALL--------EFFRRFPVV--SSAREVLRD 326 Query: 382 IEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRR 441 E +G + G ++ V D+A E P F K F G Sbjct: 327 QEFEGVLLKAGDMVMAPTVVVAMDDARNEDPLEFRLGR---------KARQHSTFGKGSH 377 Query: 442 ACLGEPLARMELFLFFTSLLQHFS-FSVPTGQPRPSHHGVFAFL 484 C G LARME+ + F + P +G+ + Sbjct: 378 TCPGAHLARMEMKVVLREWFARIPEFRIEDDAPLRYSNGIVGSV 421 >2QBO-A nrPDB Length = 421 Score = 106 bits (264), Expect = 3e-23, Method: Composition-based stats. Identities = 56/348 (16%), Positives = 107/348 (30%), Gaps = 74/348 (21%) Query: 130 EQRRFSVSTLRNLGL-GKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIAS 188 EQR+F + +G+ LE + E A L + F Sbjct: 108 EQRQFRALANQVVGMPVVDKLENRIQELACSLIESLRPQGQCNFTE-------------- 153 Query: 189 LTCGRRFEYDDPR----FLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQ 244 +Y +P F+ L L +E + ++ P + + Sbjct: 154 -------DYAEPFPIRIFMLLAGLPEEDIPHLKYLTDQMTR--------PDGSMTFAEAK 198 Query: 245 KAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFS 304 +A L ++ + R +P D + + G P + + + L Sbjct: 199 EALYDYLIPIIEQRRQ-----KPGTDAIS--IVANGQVNGRP---ITSDEAKRMCGLLLV 248 Query: 305 AGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQ 364 G+ T L++ + + P+ ++ + + + + A E+ Sbjct: 249 VGLDTVVNFLSFSMEFLAKSPEHRQELIERPERI------------------PAACEELL 290 Query: 365 RFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQ 424 R +V G + + D E G ++ KG ++ DE P Sbjct: 291 RRFSLVADG--RILTSDYEFHGVQLKKGDQILLPQMLSGLDERENACPMHVDFSR----- 343 Query: 425 GHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF-SFSVPTG 471 + + F G CLG+ LAR E+ + L FS+ G Sbjct: 344 ----QKVSHTTFGHGSHLCLGQHLARREIIVTLKEWLTRIPDFSIAPG 387 >2ZQJ-A nrPDB Length = 417 Score = 104 bits (260), Expect = 8e-23, Method: Composition-based stats. Identities = 67/461 (14%), Positives = 140/461 (30%), Gaps = 62/461 (13%) Query: 43 LGNLLHVDFQNTPYCFDQLRRRF-GDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADR 101 L N L + + R+ D+F +L + + G A + T + + Sbjct: 11 LDNSLTL-LKEGYLFIKNRTERYNSDLFQARLLGKNFICMTGAEAAKVFYDT--DRFQRQ 67 Query: 102 PPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLC 161 +P + + G A R+ +L + ++ Sbjct: 68 NALP--KRVQKSLFGVNAIQGMDGSAH-IHRKMLFLSL----MTPPHQKRLAELMTEEWK 120 Query: 162 AAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLR 221 AA L ++A ++ + C + + L + +KE + Sbjct: 121 AAVTRWEKA--DEVVLFEEA-KEILCRVAC----------YWAGVPLKETEVKERADDFI 167 Query: 222 EVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEK 281 ++++A + K R + ++ ++ + R L E E Sbjct: 168 DMVDAFGAVGP---RHWKGRRARPRAEEWIEVMIEDARAGLLKTTSGTALHEMAFHTQED 224 Query: 282 AKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQ 341 +S L V+ + + S L + L + HP + ++ G Sbjct: 225 GSQ-LDSRMAAIELINVLRPIVA-----ISYFLVFSALALHEHPKYKEWLRS------GN 272 Query: 342 VRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSS 401 R + EV+R+ P + + +D KGT+++ +L Sbjct: 273 SRE-----------REMFVQEVRRYYPFGPF-LGALVKKDFVWNNCEFKKGTSVLLDLYG 320 Query: 402 VLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGR----RACLGEPLARMELFLFF 457 D +W+ P F PE F + + + +P G C GE + + Sbjct: 321 TNHDPRLWDHPDEFRPERFAEREENL---FDMIPQGGGHAEKGHRCPGEGITIEVMKASL 377 Query: 458 TSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSP-YELCAVPR 497 L+ + VP H+ + P + + + R Sbjct: 378 DFLVHQIEYDVPEQSL---HYSLARMPSLPESGFVMSGIRR 415 >3AWQ-A nrPDB Length = 415 Score = 104 bits (259), Expect = 1e-22, Method: Composition-based stats. Identities = 31/127 (24%), Positives = 45/127 (35%), Gaps = 8/127 (6%) Query: 350 QAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVW 409 Y + EV+RF P V S+D E +G P+G ++ +L D A W Sbjct: 268 VQQPDYAELFVQEVRRFYPFFPAVVAR-ASQDFEWEGMAFPEGRQVVLDLYGSNHDAATW 326 Query: 410 EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGR----RACLGEPLARMELFLFFTSLLQHFS 465 P F PE F F+P G C GE + + + L+ Sbjct: 327 ADPQEFRPERFRAWDED---SFNFIPQGGGDHYLGHRCPGEWIVLAIMKVAAHLLVNAMR 383 Query: 466 FSVPTGQ 472 + VP Sbjct: 384 YDVPDQD 390 >3NV6-A nrPDB Length = 452 Score = 97.1 bits (240), Expect = 2e-20, Method: Composition-based stats. Identities = 54/363 (14%), Positives = 111/363 (30%), Gaps = 65/363 (17%) Query: 125 GPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAF--ANHSGRPFRPNGLLDKAV 182 P R+ L + + +E V E A+ L +F L V Sbjct: 141 PPEHTPYRKALDKGLNLAKI--RKVEDKVREVASSLIDSFAARGECDFAAEYAELFPVHV 198 Query: 183 SNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLR 242 F+ L DL E + S + R++ ++ Sbjct: 199 -------------------FMALADLPLEDIPVLSEYARQMTRPEG------NTPEEMAT 233 Query: 243 FQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADL 302 +A + DL + + + + +++ L Sbjct: 234 DLEAGNNGFYAYVDPIIRARVGGD-GDDLITLMVNSEINGE-----RIAHDKAQGLISLL 287 Query: 303 FSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHE 362 G+ T L++ ++ + HP++ ++ + ++ E Sbjct: 288 LLGGLDTVVNFLSFFMIHLARHPELVAELRSDPLKLMRGA------------------EE 329 Query: 363 VQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLD 422 + R +V M ++D E +G + +G ++ + D+A +P++ Sbjct: 330 MFRRFPVVSEA--RMVAKDQEYKGVFLKRGDMILLPTALHGLDDAANPEPWKLDFSR--- 384 Query: 423 AQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS-FSVPTGQPRPSHHGVF 481 + + F G C G LARME+ + L+ FS G+ H G+ Sbjct: 385 ------RSISHSTFGGGPHRCAGMHLARMEVIVTLEEWLKRIPEFSFKEGETPIYHSGIV 438 Query: 482 AFL 484 A + Sbjct: 439 AAV 441 >3B98-A nrPDB Length = 475 Score = 95.2 bits (235), Expect = 6e-20, Method: Composition-based stats. Identities = 73/493 (14%), Positives = 152/493 (30%), Gaps = 66/493 (13%) Query: 23 MHRRQRW--------AARYPPGPLPL-PGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQL 73 M ++ PP + P LG+ L ++ +++ + GD+F+++ Sbjct: 1 MAKKTSSVLYGRRTRRRNEPPLDKGMIPWLGHALEFG-KDAAKFLTRMKEKHGDIFTVRA 59 Query: 74 AWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRR 133 A + VL L + R + L + P ++R Sbjct: 60 AGLYITVLLDSNCYDAVLSDVAS------LDQTSYAQVLMKRIFNMILPSHNPESEKKRA 113 Query: 134 FSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGR 193 +L S++ + + L +++ Sbjct: 114 EMHFQGASLTQLSNSMQNNLRLLMTPSEMGLKTSEWK----KDGLFNLCYSLLFKTGYLT 169 Query: 194 RFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGK-VLRFQKAFLTQLD 252 F ++ L + +E + + +P LA V + +K + Sbjct: 170 VFGAENNNSAALTQIYEEFRRFDK--------------LLPKLARTTVNKEEKQIASAAR 215 Query: 253 ELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTST 312 E L + + PR+ +++L K + + +++ + G + Sbjct: 216 EKLWKWLTPSGLDRKPRE--QSWLGSYVKQLQDEGIDAEMQRRAMLLQLWVTQGNAGPAA 273 Query: 313 TLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPL 372 W + ++ HP+ R V++EI G Q + P +V+ E R Sbjct: 274 F--WVMGYLLTHPEALRAVREEIQ---GGKHLRLEERQKNTPVFDSVLWETLRLTAAA-- 326 Query: 373 GVTHMTSRDIEV-----QGFRIPKGTTLITNLS-SVLKDEAVWEKPFRFHPEHFLDAQGH 426 +T ++D ++ Q + + +G L S D + ++P F + FL+A Sbjct: 327 LITRDVTQDKKICLSNGQEYHLRRGDRLCVFPFISPQMDPQIHQQPEMFQFDRFLNADRT 386 Query: 427 FVK---------PEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSH 477 K +P+ C G A + ++L F + Sbjct: 387 EKKDFFKNGARVKYPSVPWGTEDNLCPGRHFAVHAIKELVFTILTRFDVELCD------- 439 Query: 478 HGVFAFLVSPSPY 490 LV PS Y Sbjct: 440 KNATVPLVDPSRY 452 >4C9K-A nrPDB Length = 421 Score = 90.5 bits (223), Expect = 1e-18, Method: Composition-based stats. Identities = 36/254 (14%), Positives = 71/254 (27%), Gaps = 39/254 (15%) Query: 238 GKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRI 297 + K F + ++ R DL L K P+ + Sbjct: 199 RSLEAANKGFFEYVAPIIAARRGGS-----GTDLITRILNVEIDGKPMPDDRALGLVSLL 253 Query: 298 VVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTT 357 ++ + T L + ++ + HP+ +++E Sbjct: 254 LLGG-----LDTVVNFLGFMMIYLSRHPETVAEMRREPLK------------------LQ 290 Query: 358 AVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHP 417 + E+ R +V D+E G + +G ++ + D+ + P Sbjct: 291 RGVEELFRRFAVVSDA--RYVVSDMEFHGTMLKEGDLILLPTALHGLDDRHHDDPMTVDL 348 Query: 418 EHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSH 477 + F+ G C G LAR+E+ + L + P + Sbjct: 349 SR---------RDVTHSTFAQGPHRCAGMHLARLEVTVMLQEWLARIPEFRLKDRAVPIY 399 Query: 478 HGVFAFLVSPSPYE 491 H V P E Sbjct: 400 HSGIVAAVENIPLE 413 >2IAG-A nrPDB Length = 482 Score = 88.2 bits (217), Expect = 8e-18, Method: Composition-based stats. Identities = 83/481 (17%), Positives = 155/481 (32%), Gaps = 73/481 (15%) Query: 26 RQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLA 85 R R P +P LG L ++ +++ + GD+F++ + V VL Sbjct: 1 RTRRPGEPPLDLGSIPWLGYALDFG-KDAASFLTRMKEKHGDIFTILVGGRYVTVLLDPH 59 Query: 86 AVREALVTHGEDTADRPPV-PITQILGFGPRSQGVFLARYGPA-WREQRRFSVSTLRNLG 143 + R + + R V L Y P+ + + + ++ Sbjct: 60 SYDAV------VWEPRTRLDFHAYAIFLMERIFDVQLPHYSPSDEKARMKLTL------- 106 Query: 144 LGKKSLEQWVTEEAACLCAAF-------ANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196 L + + + A +G + GLLD S + R Sbjct: 107 -----LHRELQALTEAMYTNLHAVLLGDATEAGSGWHEMGLLDF-------SYSFLLRAG 154 Query: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVL-LHIPALAGKVLRFQKA-----FLTQ 250 Y + L E ++ +V + L +P LA L ++ Sbjct: 155 YLTLYGIEALPRTHESQAQDRVHSADVFHTFRQLDRLLPKLARGSLSVGDKDHMCSVKSR 214 Query: 251 LDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTT 310 L +LL+ R+ + E++L +E E ++E + A Sbjct: 215 LWKLLSPARLARRAHRSK--WLESYLLHLE------EMGVSEEMQARALVLQLWATQGNM 266 Query: 311 STTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHM-------PYTTAVIHEV 363 W LL ++ +P+ V+ E++ ++ Q +P P +V+ E Sbjct: 267 GPAAFWLLLFLLKNPEALAAVRGELESILWQAEQPVSQTTTLPQKVLDSTPVLDSVLSES 326 Query: 364 QRFGDIVPLGVTHMTSRDIEV-----QGFRIPKGTTLITNL-SSVLKDEAVWEKPFRFHP 417 R P +T D+ + + F + +G L+ S +D ++ P F Sbjct: 327 LRL-TAAPF-ITREVVVDLAMPMADGREFNLRRGDRLLLFPFLSPQRDPEIYTDPEVFKY 384 Query: 418 EHFLDAQGHFVK---------PEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSV 468 FL+ G K +P+ AG CLG A + F +L H + Sbjct: 385 NRFLNPDGSEKKDFYKDGKRLKNYNMPWGAGHNHCLGRSYAVNSIKQFVFLVLVHLDLEL 444 Query: 469 P 469 Sbjct: 445 I 445 >3DBM-A nrPDB Length = 473 Score = 79.0 bits (193), Expect = 4e-15, Method: Composition-based stats. Identities = 72/466 (15%), Positives = 132/466 (28%), Gaps = 64/466 (13%) Query: 35 PGPLPLPGLGNL---LHVDFQNTPY--CFDQLRRRF-GDVFSLQLAWTP-------VVVL 81 PG +P + L + F +++ VF + P V+VL Sbjct: 12 PGSYGIPFFQPIKDRLEYFYGTGGRDEYFRSRMQKYQSTVFRANMPPGPFVSSNPKVIVL 71 Query: 82 NGLAAVREAL----VTHGEDTADRPPVPITQILGFGPRSQGVFLARYG-PAWREQRRFSV 136 + V + + L G R + P + + Sbjct: 72 LDAKSFPILFDVSKVEKKDLFTG--TYMPSTKLTGGYRV--LSYLDPSEPRHAQLKNLL- 126 Query: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196 + K S + + + F + V A GR + Sbjct: 127 -----FFMLKNSSNRVIPQFETTYTELFEGLEAELAKNGKAAFNDVGEQAAFRFLGRAYF 181 Query: 197 YDDPRFLRLLDLAQEGLKEESGF--LREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDEL 254 +P +L A + F + +P L P L R + Sbjct: 182 NSNPEETKLGTSAPTLISSWVLFNLAPTLDLGLPWFLQEPLLH--TFRLPAFLIKSTYNK 239 Query: 255 LTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTL 314 L ++ + + E + G P+ L V + F + TL Sbjct: 240 LYDYFQSVATP----------VMEQAEKLGVPKDEAVHNILFAVCFNTFGGVKILFPNTL 289 Query: 315 AWGLLLMILHPDVQRRVQQEIDDVIGQ--VRRPEMGDQAHMPYTTAVIHEVQRFGDIVPL 372 W L + Q + +EI I + MP T +V++E R VP Sbjct: 290 KWIGLA-GENLHTQ--LAEEIRGAIKSYGDGNVTLEAIEQMPLTKSVVYESLRIEPPVPP 346 Query: 373 GVTHMTSRDIEVQGF----RIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428 + ++ + KG L KD V+++P + P+ F+ + Sbjct: 347 QYG-KAKSNFTIESHDATFEVKKGEMLFGYQPFATKDPKVFDRPEEYVPDRFVGDGEALL 405 Query: 429 KPEAFLPFSAGR---------RACLGEPLARMELFLFFTSLLQHFS 465 K ++ +S G + C G+ + LF L + + Sbjct: 406 K---YVWWSNGPETESPTVENKQCAGKDFVVLITRLFVIELFRRYD 448 >2RCM-A nrPDB Length = 495 Score = 75.9 bits (185), Expect = 3e-14, Method: Composition-based stats. Identities = 31/154 (20%), Positives = 57/154 (37%), Gaps = 17/154 (11%) Query: 326 DVQRRVQQEIDDVIGQVR-RPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEV 384 V R+ +EI VI MG M T +V++E RF V +D+ + Sbjct: 316 QVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGR-AKKDLVI 374 Query: 385 QGF----RIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGR 440 + ++ G L +D ++++ F PE F+ +G K + +S G Sbjct: 375 ESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGE--KLLRHVLWSNGP 432 Query: 441 ---------RACLGEPLARMELFLFFTSLLQHFS 465 + C G+ + LF + + + Sbjct: 433 ETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYD 466 >2YJN-B nrPDB Length = 381 Score = 57.8 bits (138), Expect = 1e-08, Method: Composition-based stats. Identities = 19/131 (14%), Positives = 42/131 (32%), Gaps = 20/131 (15%) Query: 303 FSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHE 362 AG T+ T+ +L + P + R+ + + E Sbjct: 220 LFAGAEMTANTVVDAVLAVSAEPGLAERIADDPAA------------------AQRTVAE 261 Query: 363 VQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLD 422 V R + L + ++ + I +G ++ +++ +D V+ +P R + D Sbjct: 262 VLRLHPALHLE-RRTATAEVRLGEHVIGEGEEVVVVVAAANRDPEVFAEPDRLDVDR-PD 319 Query: 423 AQGHFVKPEAF 433 A Sbjct: 320 ADRALSAHRGH 330 >1PEQ-A nrPDB Length = 714 Score = 37.4 bits (85), Expect = 0.016, Method: Composition-based stats. Identities = 51/341 (14%), Positives = 101/341 (29%), Gaps = 44/341 (12%) Query: 46 LLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHG---EDTADRP 102 +L++ + FD+ ++ F+ + V + + LV G + R Sbjct: 22 MLNLYDKAGHIQFDKDQQAIDAFFATHVRPHSVTFASQHERLGT-LVREGYYDDAVLARY 80 Query: 103 PVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCA 162 L + G + AW+ +++ T GK+ LE + E Sbjct: 81 DRAFVLRLFEHAHASGFRFQTFLGAWKFYTSYTLKTFD----GKRYLEHF---EDRVTMV 133 Query: 163 AFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLRE 222 A G L D+ +S RF+ P FL Q+ + S FL Sbjct: 134 ALTLAQGDETLATQLTDEMLSG---------RFQPATPTFLNCGK--QQRGELVSCFLLR 182 Query: 223 VLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKA 282 + + + + A ++ + L L E + + +E A Sbjct: 183 IEDNMESIGRAVNSALQLSKRGGGV-AFLLSNLREAGAPIKRIENQSSGVIPVMKMLEDA 241 Query: 283 KGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342 + AG + L HPD+ R + + ++ ++ Sbjct: 242 FS----------YANQLGARQGAG----------AVYLHAHHPDILRFLDTKRENADEKI 281 Query: 343 RRPEMGDQAHMPYTT-AVIHEVQRFGDIVPLGVTHMTSRDI 382 R + +P T + E + P + + Sbjct: 282 RIKTLSLGVVIPDITFRLAKENAQMALFSPYDIQRRYGKPF 322 >4YXC-B nrPDB Length = 227 Score = 34.7 bits (78), Expect = 0.084, Method: Composition-based stats. Identities = 23/171 (13%), Positives = 56/171 (32%), Gaps = 29/171 (16%) Query: 232 HIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQP---PRDLTEAFLAEMEKAKGNPES 288 +P L + + +++ L+ + + QP P D L ++ N + Sbjct: 58 GVPVLTSQYGTVNGQYALRVEHLINPILNSLNEEQPKNNPSDENTGALDDLWADALNEQK 117 Query: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMG 348 + ++ V G ++ + Q+ID ++ + + Sbjct: 118 ATTTKSAADAVFQQLGGGD------VSGAM--------------QDIDLIMDIPVKLTVE 157 Query: 349 DQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSR--DIEVQGFRIPKGTTLIT 397 + T I E+ R + + + DI + G+ I +G ++ Sbjct: 158 ----LGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVV 204 >4YXB-D nrPDB Length = 80 Score = 32.4 bits (72), Expect = 0.45, Method: Composition-based stats. Identities = 9/48 (18%), Positives = 19/48 (39%), Gaps = 2/48 (4%) Query: 352 HMPYTTAVIHEVQRFGDIVPLGVTHMTSR--DIEVQGFRIPKGTTLIT 397 + T I E+ R + + + DI + G+ I +G ++ Sbjct: 10 ELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVV 57 >2Z61-A nrPDB Length = 370 Score = 32.4 bits (72), Expect = 0.45, Method: Composition-based stats. Identities = 15/145 (10%), Positives = 36/145 (24%), Gaps = 7/145 (4%) Query: 72 QLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQ 131 W V++ + L P + L + + + + Sbjct: 226 MTGWRIGYVISNDEIIEAILKLQQNLFISAPTISQYAALKAFEKETEREINSMIKEFDRR 285 Query: 132 RRFSVSTLRNLG------LGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNV 185 RR + +++ G +G + + E+ P N Sbjct: 286 RRLVLKYVKDFGWEVNNPIGAYYVFPNIGEDGREFAYKLLKEKFVALTPGIGFGSKGKNY 345 Query: 186 IASLTCGRRFEYDDPRFLRLLDLAQ 210 I ++ +E R+ + Sbjct: 346 I-RISYANSYENIKEGLERIKEFLN 369 >3T1O-A nrPDB Length = 198 Score = 31.2 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 31/81 (38%), Gaps = 5/81 (6%) Query: 223 VLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWD-----PAQPPRDLTEAFLA 277 +L V ++ + A LR + + E L E+ +T D RDL +A Sbjct: 94 ILRGVDGIVFVADSAPNRLRANAESMRNMRENLAEYGLTLDDVPIVIQVNKRDLPDALPV 153 Query: 278 EMEKAKGNPESSFNDENLRIV 298 EM +A +PE F Sbjct: 154 EMVRAVVDPEGKFPVLEAVAT 174 >5L9W-B nrPDB Length = 732 Score = 29.7 bits (65), Expect = 3.4, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 33/86 (38%), Gaps = 5/86 (5%) Query: 253 ELLTEHRMTWDPAQP----PRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMV 308 + + E R +P RDL + E + G+ ++E++R + L G Sbjct: 116 QRVAERRNIAVQNKPLPLIERDLILG-VRERIDSSGSVVRPLDEEDVRTKLRMLMDRGAR 174 Query: 309 TTSTTLAWGLLLMILHPDVQRRVQQE 334 +L W + V+ +++E Sbjct: 175 AIVVSLLWSFMNPAHEKRVREIIREE 200 >3WEN-A nrPDB Length = 913 Score = 29.3 bits (64), Expect = 3.8, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 27/81 (33%), Gaps = 5/81 (6%) Query: 85 AAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGL 144 A REALV + RP + + + W + ++S+ T+ N GL Sbjct: 533 QATREALVRTSNE---RPFLLSRSTFAGSGKYTAHWTGDNAARWDDL-QYSIPTMLNFGL 588 Query: 145 -GKKSLEQWVTEEAACLCAAF 164 G + + A Sbjct: 589 FGMPMIGADICGFAESTTEEL 609 >6FOP-A nrPDB Length = 717 Score = 29.3 bits (64), Expect = 4.2, Method: Composition-based stats. Identities = 8/43 (18%), Positives = 17/43 (39%) Query: 314 LAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYT 356 + L + P+ ++ +E+ G + P D +M Y Sbjct: 581 ITAASLYLGKDPNYIKQNYEEMLRECGTSQPPNWKDIQYMYYA 623 >1QVR-A nrPDB Length = 854 Score = 29.3 bits (64), Expect = 4.3, Method: Composition-based stats. Identities = 19/111 (17%), Positives = 41/111 (36%), Gaps = 5/111 (4%) Query: 163 AFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLRE 222 + GR + SN+ + L + P + R+ D + + F E Sbjct: 688 RLTDSHGRTVDFRNTVIILTSNLGSPLIL-EGLQKGWP-YERIRDEVFKV--LQQHFRPE 743 Query: 223 VLNAVPVLLHI-PALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLT 272 LN + ++ P ++ + + L+ L L E R++ + + +D Sbjct: 744 FLNRLDEIVVFRPLTKEQIRQIVEIQLSYLRARLAEKRISLELTEAAKDFL 794 >5UE8-A nrPDB Length = 961 Score = 29.3 bits (64), Expect = 4.5, Method: Composition-based stats. Identities = 25/134 (18%), Positives = 43/134 (32%), Gaps = 19/134 (14%) Query: 137 STLRNLG-LGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRF 195 + + L K + V + L A A +NV AS Sbjct: 361 QAMTHFACLSSKYMCPGVPAVMSTLLAN--------INAYYAHTTASTNVSASDRFAAS- 411 Query: 196 EYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELL 255 + RF++LLD L+ + R + PA + + L+ K+ + L + Sbjct: 412 NFGKERFVKLLDQLHNSLRIDLSMYRN---------NFPASSPERLQDLKSTVDLLTSIT 462 Query: 256 TEHRMTWDPAQPPR 269 + PPR Sbjct: 463 FFRMKVQELQSPPR 476 >4DJD-D nrPDB Length = 323 Score = 28.9 bits (63), Expect = 4.6, Method: Composition-based stats. Identities = 10/49 (20%), Positives = 19/49 (38%), Gaps = 10/49 (20%) Query: 296 RIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRR 344 + L AG +L++ HP+ RV++ ID ++ Sbjct: 285 AVTATALLQAGAH----------ILLMRHPEAVARVKENIDQLMVSNAY 323 >4LJ8-A nrPDB Length = 339 Score = 28.9 bits (63), Expect = 5.3, Method: Composition-based stats. Identities = 19/111 (17%), Positives = 41/111 (36%), Gaps = 5/111 (4%) Query: 163 AFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLRE 222 + GR + SN+ + L + P + R+ D + + F E Sbjct: 173 RLTDSHGRTVDFRNTVIILTSNLGSPLIL-EGLQKGWP-YERIRDEVFKV--LQQHFRPE 228 Query: 223 VLNAVPVLLHI-PALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLT 272 LN + ++ P ++ + + L+ L L E R++ + + +D Sbjct: 229 FLNRLDEIVVFRPLTKEQIRQIVEIQLSYLRARLAEKRISLELTEAAKDFL 279 >3RP9-A nrPDB Length = 458 Score = 28.9 bits (63), Expect = 5.6, Method: Composition-based stats. Identities = 10/59 (16%), Positives = 21/59 (35%), Gaps = 5/59 (8%) Query: 322 ILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMP---YTTAVIHEVQRFGDIVPLGVTHM 377 + HP + E++ + R D +M A + E+QR+ + + Sbjct: 395 LAHPFFKEVRIAEVETNATEKVRLPFNDWMNMDEPQLRYAFVKEIQRYHP--EIQLPRR 451 >3OLM-A nrPDB Length = 429 Score = 28.5 bits (62), Expect = 7.2, Method: Composition-based stats. Identities = 20/106 (18%), Positives = 37/106 (34%), Gaps = 9/106 (8%) Query: 198 DDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTE 257 DDPR LD K + + P L +P +R + F E++ Sbjct: 36 DDPRLPSSLDQNVPQYKRDFRRKVIYFRSQPALRILPGQCHIKVRRKNIFEDAYQEIMR- 94 Query: 258 HRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLF 303 Q P DL + + + + +G + E ++ ++F Sbjct: 95 --------QTPEDLKKRLMIKFDGEEGLDYGGVSREFFFLLSHEMF 132 >3GFZ-A nrPDB Length = 413 Score = 28.1 bits (61), Expect = 9.2, Method: Composition-based stats. Identities = 25/180 (13%), Positives = 45/180 (25%), Gaps = 23/180 (12%) Query: 258 HRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWG 317 +R P +PP D L + + + + F + T L Sbjct: 15 YRSQVHPDRPPVD-----LDALVHRASSKNLPLGITGILLFNGLQFFQVLEGTEEALESL 69 Query: 318 LLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPY--TTAVIHEVQRFGDIVPLGVT 375 + P + V+ D + + T + E+ RF Sbjct: 70 FSEIQSDPRHRDVVELMRDYSAYRRFHGTGMRILDLRLFETDGALEEILRFSTF------ 123 Query: 376 HMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLP 435 G P + LS+ + D + P P ++ LP Sbjct: 124 ----------GVTEPVNDRMFRLLSAFIADGGRYCLPEPLQPSRWMMMPASGTAAPQHLP 173 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.130 0.344 Lambda K H 0.267 0.0401 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,111,037 Number of Sequences: 36641 Number of extensions: 730875 Number of successful extensions: 3441 Number of sequences better than 10.0: 188 Number of HSP's better than 10.0 without gapping: 268 Number of HSP's successfully gapped in prelim test: 77 Number of HSP's that attempted gapping in prelim test: 2464 Number of HSP's gapped (non-prelim): 380 length of query: 497 length of database: 10,336,785 effective HSP length: 101 effective length of query: 396 effective length of database: 6,636,044 effective search space: 2627873424 effective search space used: 2627873424 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (20.9 bits) S2: 61 (28.1 bits)