BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P10632 (490 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2NNH-A nrPDB 962 0.0 4GQS-A nrPDB 769 0.0 5W0C-A nrPDB 764 0.0 1N6B-A nrPDB 719 0.0 3E6I-A nrPDB 577 e-165 4H1N-A nrPDB 531 e-151 5E58-A nrPDB 515 e-146 5E0E-A nrPDB 514 e-146 3IBD-A nrPDB 491 e-139 2PG7-A nrPDB 487 e-138 3TBG-A nrPDB 347 1e-95 3DL9-A nrPDB 296 1e-80 4R20-A nrPDB 249 2e-66 6B82-A nrPDB 236 2e-62 6DWN-A nrPDB 229 2e-60 6IQ5-A nrPDB 225 3e-59 4R1Z-A nrPDB 217 1e-56 2HI4-A nrPDB 204 7e-53 5UYS-A nrPDB 189 2e-48 5VBU-A nrPDB 184 8e-47 3QZ1-A nrPDB 172 3e-43 5YLW-A nrPDB 160 2e-39 6DA2-A nrPDB 121 8e-28 5VEU-A nrPDB 116 2e-26 3K9V-A nrPDB 99 5e-21 3MDV-A nrPDB 92 4e-19 2VE3-A nrPDB 80 2e-15 3S79-A nrPDB 78 1e-14 3EL3-A nrPDB 74 1e-13 3N9Z-A nrPDB 71 1e-12 6C94-A nrPDB 70 2e-12 6AYB-A nrPDB 69 3e-12 3MZS-A nrPDB 67 2e-11 4KPA-A nrPDB 66 3e-11 2WX2-A nrPDB 65 1e-10 4ZGX-A nrPDB 62 6e-10 4OQR-A nrPDB 61 1e-09 5VWS-A nrPDB 60 1e-09 2VZM-A nrPDB 60 2e-09 3A1L-A nrPDB 60 3e-09 4OQS-A nrPDB 59 3e-09 5FSA-A nrPDB 59 4e-09 2W0A-A nrPDB 59 6e-09 5FOI-A nrPDB 59 7e-09 1Q5D-A nrPDB 58 8e-09 3TYW-A nrPDB 58 1e-08 3EJB-B nrPDB 57 2e-08 5YSW-A nrPDB 57 2e-08 2ZBZ-A nrPDB 55 5e-08 6M7X-A nrPDB 55 5e-08 6M7L-A nrPDB 55 7e-08 6GK6-A nrPDB 55 8e-08 5CJE-A nrPDB 55 9e-08 6GMF-A nrPDB 54 1e-07 2Y5N-A nrPDB 54 2e-07 4RM4-A nrPDB 54 2e-07 2X2N-A nrPDB 53 2e-07 3ABB-A nrPDB 53 3e-07 6B11-A nrPDB 53 3e-07 3SN5-A nrPDB 52 4e-07 6F0B-A nrPDB 52 5e-07 6CR2-A nrPDB 51 1e-06 4UBS-A nrPDB 51 1e-06 4GGV-A nrPDB 51 1e-06 3L4D-A nrPDB 51 1e-06 3TKT-A nrPDB 51 1e-06 4TRI-A nrPDB 50 2e-06 4WPZ-A nrPDB 50 2e-06 3R9C-A nrPDB 50 2e-06 2Z36-A nrPDB 50 3e-06 5EX6-C nrPDB 49 4e-06 4YZR-A nrPDB 49 5e-06 5L1U-A nrPDB 49 5e-06 1Z8P-A nrPDB 49 6e-06 6F88-A nrPDB 49 6e-06 5IT1-A nrPDB 49 6e-06 5Z9I-A nrPDB 49 6e-06 3MGX-A nrPDB 49 7e-06 5LIV-A nrPDB 49 7e-06 3P3Z-A nrPDB 47 2e-05 6FSH-A nrPDB 47 2e-05 1CPT-A nrPDB 47 2e-05 1EHE-A nrPDB 46 3e-05 4TX3-A nrPDB 46 4e-05 4WMZ-A nrPDB 46 4e-05 2XKR-A nrPDB 46 4e-05 4MM0-A nrPDB 46 4e-05 3JUS-A nrPDB 45 6e-05 5NWS-A nrPDB 45 6e-05 3A50-A nrPDB 45 7e-05 5JLC-A nrPDB 45 7e-05 1WIY-A nrPDB 45 8e-05 2RFC-A nrPDB 45 9e-05 6A7I-A nrPDB 44 1e-04 5OFQ-A nrPDB 44 1e-04 5Y1I-A nrPDB 44 2e-04 2IJ7-A nrPDB 44 2e-04 3ABA-A nrPDB 44 2e-04 6GII-A nrPDB 43 4e-04 5YHJ-A nrPDB 43 4e-04 1UED-A nrPDB 43 4e-04 6A7J-A nrPDB 42 4e-04 2WIO-A nrPDB 42 6e-04 6CVC-A nrPDB 42 6e-04 2WM5-A nrPDB 42 7e-04 5FYF-A nrPDB 42 7e-04 5GWE-A nrPDB 42 7e-04 5XW2-A nrPDB 42 9e-04 5XJN-A nrPDB 41 0.001 4YT3-A nrPDB 41 0.001 6FYJ-A nrPDB 41 0.001 1LG9-A nrPDB 40 0.002 5XNT-A nrPDB 40 0.002 3OO3-A nrPDB 40 0.002 4Z5P-A nrPDB 40 0.002 3RWL-A nrPDB 40 0.003 3WVS-A nrPDB 39 0.005 5LIE-A nrPDB 38 0.008 2IAG-A nrPDB 38 0.010 5HDI-A nrPDB 38 0.011 5L94-A nrPDB 38 0.011 6G71-A nrPDB 38 0.013 5M0P-A nrPDB 37 0.014 1UE8-A nrPDB 37 0.018 1GWI-A nrPDB 37 0.018 4JBT-A nrPDB 37 0.020 4Z5Q-A nrPDB 37 0.020 4DO1-A nrPDB 36 0.031 6HQD-A nrPDB 35 0.074 5HIW-A nrPDB 35 0.074 5DQN-A nrPDB 35 0.085 3IVY-A nrPDB 35 0.086 2QBO-A nrPDB 35 0.10 5KYO-A nrPDB 34 0.12 1F4U-A nrPDB 34 0.14 3NV6-A nrPDB 33 0.29 3B98-A nrPDB 33 0.30 2NZA-A nrPDB 33 0.31 5DE9-A nrPDB 33 0.37 3AWQ-A nrPDB 32 0.47 2ZQJ-A nrPDB 32 0.51 4C9K-A nrPDB 32 0.58 2FR7-A nrPDB 32 0.80 4XE3-A nrPDB 32 0.92 1ODO-A nrPDB 31 1.0 3OFT-A nrPDB 31 1.3 1PIO-A nrPDB 31 1.4 2UUQ-A nrPDB 31 1.5 2JGU-A nrPDB 31 1.5 2VWK-A nrPDB 30 1.7 4DJD-D nrPDB 30 2.0 3MCR-A nrPDB 30 2.0 6BLD-A nrPDB 30 2.3 2GU2-A nrPDB 30 2.8 2KU2-A nrPDB 30 2.9 5H12-A nrPDB 29 3.8 1D5A-A nrPDB 29 3.8 3T3N-A nrPDB 29 4.9 3BUJ-A nrPDB 28 6.2 >2NNH-A nrPDB Length = 476 Score = 962 bits (2488), Expect = 0.0, Method: Compositional matrix adjust. Identities = 463/472 (98%), Positives = 468/472 (99%) Query: 19 LWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFH 78 + +++ + KLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFH Sbjct: 1 MAKKTSSKGKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFH 60 Query: 79 GYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGK 138 GYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGK Sbjct: 61 GYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGK 120 Query: 139 RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM 198 RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM Sbjct: 121 RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM 180 Query: 199 KRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVN 258 KRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVN Sbjct: 181 KRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVN 240 Query: 259 NPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPE 318 NPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPE Sbjct: 241 NPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPE 300 Query: 319 VTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRN 378 VTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRN Sbjct: 301 VTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRN 360 Query: 379 YLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGE 438 YLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGE Sbjct: 361 YLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGE 420 Query: 439 GLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIPV 490 GLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIPV Sbjct: 421 GLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIPV 472 >4GQS-A nrPDB Length = 477 Score = 769 bits (1986), Expect = 0.0, Method: Compositional matrix adjust. Identities = 364/470 (77%), Positives = 411/470 (87%) Query: 21 RQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGY 80 + S R KLPPGPTPLP+IGN+LQID+KD+ KS TN SK+YGPVFT+YFG+ +VV HGY Sbjct: 4 KTSSGRGKLPPGPTPLPVIGNILQIDIKDVSKSLTNLSKIYGPVFTLYFGLERMVVLHGY 63 Query: 81 EAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRS 140 E VKEALID GEEFSGRG+ P+++R +G GI+ SNGKRWKEIRRFSL TLRNFGMGKRS Sbjct: 64 EVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRS 123 Query: 141 IEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKR 200 IEDRVQEEA CLVEELRKTKASPCDPTFILGCAPCNVICS++FQKRFDYKDQ FL LM++ Sbjct: 124 IEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQFLNLMEK 183 Query: 201 FNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNP 260 NEN RI+++PWIQ+CNNFP +ID FPGTHNK+LKN+A S I EKVKEHQ S+D+NNP Sbjct: 184 LNENIRIVSTPWIQICNNFPTIIDYFPGTHNKLLKNLAFMESDILEKVKEHQESMDINNP 243 Query: 261 RDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVT 320 RDFIDCFLIKME+EK NQ+SEF IENLV T ADL AGTETTSTTLRY LLLLLKHPEVT Sbjct: 244 RDFIDCFLIKMEKEKQNQQSEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVT 303 Query: 321 AKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYL 380 AKVQEEI+ V+GR+RSPCMQDR HMPYTDAVVHE+QRY DL+PT +PHAVT D KFRNYL Sbjct: 304 AKVQEEIERVVGRNRSPCMQDRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYL 363 Query: 381 IPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGL 440 IPKGTTI+ LTSVLHD+KEFPNP +FDP HFLD+ GNFKKS+YFMPFSAGKRIC GEGL Sbjct: 364 IPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGL 423 Query: 441 ARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIPV 490 ARMELFLFLT ILQNFNLKS+ D K+L+TT V G S+PP YQ+CFIP+ Sbjct: 424 ARMELFLFLTFILQNFNLKSLIDPKDLDTTPVVNGFASVPPFYQLCFIPI 473 >5W0C-A nrPDB Length = 477 Score = 764 bits (1973), Expect = 0.0, Method: Compositional matrix adjust. Identities = 365/470 (77%), Positives = 408/470 (86%) Query: 21 RQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGY 80 + S R KLPPGPTPLP+IGN+LQI +KDI KS TN SKVYGPVFT+YFG+ PIVV HGY Sbjct: 4 KTSSGRGKLPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGY 63 Query: 81 EAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRS 140 EAVKEALID GEEFSGRG P+++R +G GI+ SNGK+WKEIRRFSL TLRNFGMGKRS Sbjct: 64 EAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRS 123 Query: 141 IEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKR 200 IEDRVQEEA CLVEELRKTKASPCDPTFILGCAPCNVICS++F KRFDYKDQ FL LM++ Sbjct: 124 IEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEK 183 Query: 201 FNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNP 260 NEN +IL+SPWIQ+CNNF +ID FPGTHNK+LKNVA +SYI EKVKEHQ S+D+NNP Sbjct: 184 LNENIKILSSPWIQICNNFSPIIDYFPGTHNKLLKNVAFMKSYILEKVKEHQESMDMNNP 243 Query: 261 RDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVT 320 +DFIDCFL+KME+EK NQ SEF IE+L T DLF AGTETTSTTLRY LLLLLKHPEVT Sbjct: 244 QDFIDCFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVT 303 Query: 321 AKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYL 380 AKVQEEI+ VIGR+RSPCMQDRSHMPYTDAVVHE+QRY DL+PT +PHAVT D KFRNYL Sbjct: 304 AKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYL 363 Query: 381 IPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGL 440 IPKGTTI+ LTSVLHD+KEFPNP +FDP HFLD+ GNFKKS YFMPFSAGKRIC GE L Sbjct: 364 IPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEAL 423 Query: 441 ARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIPV 490 A MELFLFLT+ILQNFNLKS+ D KNL+TT V G S+PP YQ+CFIP+ Sbjct: 424 AGMELFLFLTSILQNFNLKSLVDPKNLDTTPVVNGFASVPPFYQLCFIPI 473 >1N6B-A nrPDB Length = 473 Score = 719 bits (1856), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/472 (72%), Positives = 395/472 (83%), Gaps = 3/472 (0%) Query: 19 LWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFH 78 + +++ + KLPPGPTP PIIGN+LQID KDI KS T FS+ YGPVFTVY GM P VV H Sbjct: 1 MAKKTSSKGKLPPGPTPFPIIGNILQIDAKDISKSLTKFSECYGPVFTVYLGMKPTVVLH 60 Query: 79 GYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGK 138 GYEAVKEAL+D GEEF+GRG+ PI ++++KGLGI SN K WKE+RRFSL TLRNFGMGK Sbjct: 61 GYEAVKEALVDLGEEFAGRGSVPILEKVSKGLGIAFSNAKTWKEMRRFSLMTLRNFGMGK 120 Query: 139 RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM 198 RSIEDR+QEEA CLVEELRKT ASPCDPTFILGCAPCNVICSV+F RFDYKD+ FL LM Sbjct: 121 RSIEDRIQEEARCLVEELRKTNASPCDPTFILGCAPCNVICSVIFHNRFDYKDEEFLKLM 180 Query: 199 KRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVN 258 + +EN +L +PW+QV NNFP L+D FPG H +LKN +++I EKVKEHQ LDVN Sbjct: 181 ESLHENVELLGTPWLQVYNNFPALLDYFPGIHKTLLKNADYIKNFIMEKVKEHQKLLDVN 240 Query: 259 NPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPE 318 NPRDFIDCFLIKMEQE + EF +E+LV V+DLF AGTETTSTTLRY LLLLLKHPE Sbjct: 241 NPRDFIDCFLIKMEQENN---LEFTLESLVIAVSDLFGAGTETTSTTLRYSLLLLLKHPE 297 Query: 319 VTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRN 378 V A+VQEEI+ VIGRHRSPCMQDRS MPYTDAV+HEIQR+ DL+PT +PHAVT D +FRN Sbjct: 298 VAARVQEEIERVIGRHRSPCMQDRSRMPYTDAVIHEIQRFIDLLPTNLPHAVTRDVRFRN 357 Query: 379 YLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGE 438 Y IPKGT I+ LTSVLHD+K FPNP +FDPGHFLD++GNFKKSDYFMPFSAGKR+C GE Sbjct: 358 YFIPKGTDIITSLTSVLHDEKAFPNPKVFDPGHFLDESGNFKKSDYFMPFSAGKRMCVGE 417 Query: 439 GLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIPV 490 GLARMELFLFLT+ILQNF L+S+ + K+L+ TAV G VS+PPSYQ+CFIP+ Sbjct: 418 GLARMELFLFLTSILQNFKLQSLVEPKDLDITAVVNGFVSVPPSYQLCFIPI 469 >3E6I-A nrPDB Length = 476 Score = 577 bits (1486), Expect = e-165, Method: Compositional matrix adjust. Identities = 269/471 (57%), Positives = 352/471 (74%), Gaps = 1/471 (0%) Query: 19 LWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFH 78 + +++ + KLPPGP PLPIIGN+ Q+++K+I KSFT ++ +GPVFT+Y G +VV H Sbjct: 1 MAKKTSSKGKLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 60 Query: 79 GYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGK 138 GY+AVKEAL+D +EFSGRG+ P + + GII +NG WK+IRRFSLTTLRN+GMGK Sbjct: 61 GYKAVKEALLDYKDEFSGRGDLP-AFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGK 119 Query: 139 RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM 198 + E R+Q EAH L+E LRKT+ P DPTF++GCAPCNVI ++F+K FDY D+ FL LM Sbjct: 120 QGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLM 179 Query: 199 KRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVN 258 FNENF +L++PW+Q+ NNFP + PG+H KV+KNVA + Y+ E+VKEH SLD N Sbjct: 180 YLFNENFHLLSTPWLQLYNNFPSFLHYLPGSHRKVIKNVAEVKEYVSERVKEHHQSLDPN 239 Query: 259 NPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPE 318 PRD DC L++ME+EK + + + ++ + TVADLF AGTETTSTTLRYGLL+L+K+PE Sbjct: 240 CPRDLTDCLLVEMEKEKHSAERLYTMDGITVTVADLFFAGTETTSTTLRYGLLILMKYPE 299 Query: 319 VTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRN 378 + K+ EEID VIG R P ++DR MPY DAVVHEIQR+ LVP+ +PH T DT FR Sbjct: 300 IEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRG 359 Query: 379 YLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGE 438 YLIPKGT ++ L SVL+D++EFP+P F P HFL++NG FK SDYF PFS GKR+CAGE Sbjct: 360 YLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFSTGKRVCAGE 419 Query: 439 GLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIP 489 GLARMELFL L ILQ+FNLK + D K+++ + + G +PP Y++C IP Sbjct: 420 GLARMELFLLLCAILQHFNLKPLVDPKDIDLSPIHIGFGCIPPRYKLCVIP 470 >4H1N-A nrPDB Length = 479 Score = 531 bits (1368), Expect = e-151, Method: Compositional matrix adjust. Identities = 250/470 (53%), Positives = 343/470 (72%) Query: 19 LWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFH 78 + +++ + KLPPGP+PLP++GN+LQ+D K + +SF + YG VFTVY G P+VV Sbjct: 1 MAKKTSSKGKLPPGPSPLPVLGNLLQMDRKGLLRSFLRLREKYGDVFTVYLGSRPVVVLC 60 Query: 79 GYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGK 138 G +A++EAL+D E FSGRG + I +G G+I +NG+RW+ +RRFSL T+R+FGMGK Sbjct: 61 GTDAIREALVDQAEAFSGRGKIAVVDPIFQGYGVIFANGERWRALRRFSLATMRDFGMGK 120 Query: 139 RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM 198 RS+E+R+QEEA CLVEELRK+K + D T + N+ICS+VF KRFDYKD FL L+ Sbjct: 121 RSVEERIQEEARCLVEELRKSKGALLDNTLLFHSITSNIICSIVFGKRFDYKDPVFLRLL 180 Query: 199 KRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVN 258 F ++F +++S QV F + FPGTH ++ +N+ ++I + V++H+A+LD + Sbjct: 181 DLFFQSFSLISSFSSQVFELFSGFLKYFPGTHRQIYRNLQEINTFIGQSVEKHRATLDPS 240 Query: 259 NPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPE 318 NPRDFID +L++ME++K + SEF+ +NL+ TV LF AGTETTSTTLRYG LL+LK+P Sbjct: 241 NPRDFIDVYLLRMEKDKSDPSSEFHHQNLILTVLSLFAAGTETTSTTLRYGFLLMLKYPH 300 Query: 319 VTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRN 378 VT +VQ+EI+ VIG HR P + DR+ MPYTDAV+HEIQR DL+P GVPH VT DT+FR Sbjct: 301 VTERVQKEIEQVIGSHRPPALDDRAKMPYTDAVIHEIQRLGDLIPFGVPHTVTKDTQFRG 360 Query: 379 YLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGE 438 Y+IPK T + +L+S LHD + F PN F+PGHFLD NG K+++ FMPFS GKRIC GE Sbjct: 361 YVIPKNTEVFPVLSSALHDPRYFETPNTFNPGHFLDANGALKRNEGFMPFSLGKRICLGE 420 Query: 439 GLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFI 488 G+AR ELFLF TTILQNF++ S ++++ T G+ ++PPSYQI F+ Sbjct: 421 GIARTELFLFFTTILQNFSIASPVPPEDIDLTPRESGVGNVPPSYQIRFL 470 >5E58-A nrPDB Length = 493 Score = 515 bits (1326), Expect = e-146, Method: Compositional matrix adjust. Identities = 239/448 (53%), Positives = 319/448 (71%) Query: 41 NMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNS 100 N+LQ+D SF + YG VFTV+ G P+V+ +G EA++EAL+D E FSGRG Sbjct: 42 NLLQMDRGGFLNSFMRIREKYGDVFTVHLGPRPVVMLYGTEAIREALVDQAEAFSGRGTI 101 Query: 101 PISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTK 160 + + + G+I SNG+RWK +RRFSL T+R+FGMGKRS+EDR+QEEA CLVEEL+K++ Sbjct: 102 AVIKPVIGDYGMIFSNGERWKVLRRFSLATMRDFGMGKRSVEDRIQEEAQCLVEELQKSQ 161 Query: 161 ASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFP 220 +P DPTF+ C N+ICS+VF +R+DYKD+ FL L+ F F +++S QV F Sbjct: 162 GAPLDPTFLFQCITANIICSIVFGERYDYKDRQFLRLLDLFYRTFSLMSSFSSQVFELFS 221 Query: 221 LLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKS 280 + FPG H ++ +N+ Y+ + V++H+A+LD +NPRDFID +L++ME+EK NQ + Sbjct: 222 GFMKYFPGAHRQITRNLQEILDYVGQSVEKHRATLDPSNPRDFIDTYLLRMEKEKSNQHT 281 Query: 281 EFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQ 340 EF+ +NL+ +V LF AGTETTSTTLRYG LL+LK+P V KVQ+EID VIG HR P ++ Sbjct: 282 EFHHQNLLISVLSLFFAGTETTSTTLRYGFLLMLKYPHVAEKVQKEIDQVIGSHRLPTLE 341 Query: 341 DRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKE 400 DR+ MPYTDAV+HEIQR+SDL P G PH VT DT FR YL+PK T + +L+S LHD + Sbjct: 342 DRTKMPYTDAVIHEIQRFSDLAPIGAPHKVTKDTLFRGYLLPKNTEVYPILSSALHDPQY 401 Query: 401 FPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKS 460 F P F+P HFLD NG KKS+ FMPFS GKRIC GEG+AR ELFLF TTILQNF++ S Sbjct: 402 FEQPGTFNPDHFLDANGALKKSEAFMPFSIGKRICLGEGIARNELFLFFTTILQNFSVSS 461 Query: 461 VDDLKNLNTTAVTKGIVSLPPSYQICFI 488 K+++ + GI +P +YQI F+ Sbjct: 462 SVAPKDIDLSPKESGIGKVPQTYQISFL 489 >5E0E-A nrPDB Length = 463 Score = 514 bits (1323), Expect = e-146, Method: Compositional matrix adjust. Identities = 240/448 (53%), Positives = 325/448 (72%) Query: 41 NMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNS 100 N+LQ+D SF + YG VFTV+ G P+V+ +G EA++EAL+D E FSGRG Sbjct: 14 NLLQMDRGGFLNSFRRIREKYGDVFTVHLGPRPVVMLYGTEAIREALVDQAEAFSGRGTI 73 Query: 101 PISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTK 160 + + I +G G++ +NG+RWK +RRFSL T+R+FGMGKRS+E+R+QEEA CLVEE RK++ Sbjct: 74 AVVEPIFRGYGVVFANGERWKALRRFSLVTMRDFGMGKRSVEERIQEEARCLVEEFRKSQ 133 Query: 161 ASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFP 220 +P DPTF+ C N+ICS+VF +RFDYKD FL L+ F ++F +++S QV F Sbjct: 134 GAPLDPTFLFQCITANIICSIVFGERFDYKDHQFLRLLYLFYQSFSLISSFSSQVFELFS 193 Query: 221 LLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKS 280 + FPGTH ++ +N+ YI + V++H+A+LD ++PRDFID +L++ME+EK NQ + Sbjct: 194 GFLKYFPGTHRQISRNLQEILDYIGQSVEKHRATLDPSHPRDFIDTYLLRMEKEKSNQHT 253 Query: 281 EFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQ 340 EF+ +NLV +V LF AGTET+STTLRYG LL+LK+P V KVQ+EID VIG HR P ++ Sbjct: 254 EFDHQNLVISVLSLFFAGTETSSTTLRYGFLLMLKYPHVAEKVQKEIDQVIGSHRLPTLE 313 Query: 341 DRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKE 400 DR+ MPYT+AV++EIQR+SDL+P GVPH VT DT FR YL+PK T + +L+S LHD + Sbjct: 314 DRTKMPYTEAVIYEIQRFSDLIPIGVPHKVTKDTLFRGYLLPKNTEVYPILSSALHDPQY 373 Query: 401 FPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKS 460 F P+ F+P HFLD NG KKS+ FMPFS GKRIC GEG+AR ELFLF TTILQNF+L S Sbjct: 374 FEQPDTFNPDHFLDANGALKKSEAFMPFSIGKRICLGEGIARNELFLFFTTILQNFSLSS 433 Query: 461 VDDLKNLNTTAVTKGIVSLPPSYQICFI 488 K+++ + G +P +YQICF+ Sbjct: 434 PVAPKDIDLSPKESGFGKVPQTYQICFL 461 >3IBD-A nrPDB Length = 476 Score = 491 bits (1263), Expect = e-139, Method: Compositional matrix adjust. Identities = 230/449 (51%), Positives = 313/449 (69%) Query: 41 NMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNS 100 N+LQ+D + + KSF F + YG VFTV+ G P+V+ G EA++EAL+D E FSGRG Sbjct: 23 NLLQMDRRGLLKSFLRFREKYGDVFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKI 82 Query: 101 PISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTK 160 + +G G+I +NG RWK +RRFS+TT+R+FGMGKRS+E+R+QEEA CL+EELRK+K Sbjct: 83 AMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKSK 142 Query: 161 ASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFP 220 + DPTF+ N+ICS+VF KRF Y+DQ FL ++ F + F +++S + Q+ F Sbjct: 143 GALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFELFS 202 Query: 221 LLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKS 280 + FPG H +V KN+ +YI V++H+ +LD + PRD ID +L+ ME+EK N S Sbjct: 203 GFLKHFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPSAPRDLIDTYLLHMEKEKSNAHS 262 Query: 281 EFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQ 340 EF+ +NL LF AGTETTSTTLRYG LL+LK+P V +V EI+ VIG HR P + Sbjct: 263 EFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGPHRPPELH 322 Query: 341 DRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKE 400 DR+ MPYT+AV++EIQR+SDL+P GVPH VT T FR Y+IPK T + +L++ LHD Sbjct: 323 DRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILSTALHDPHY 382 Query: 401 FPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKS 460 F P+ F+P HFLD NG KK++ F+PFS GKRIC GEG+AR ELFLF TTILQNF++ S Sbjct: 383 FEKPDAFNPDHFLDANGALKKTEAFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMAS 442 Query: 461 VDDLKNLNTTAVTKGIVSLPPSYQICFIP 489 ++++ T G+ +PP+YQI F+P Sbjct: 443 PVAPEDIDLTPQECGVGKIPPTYQIRFLP 471 >2PG7-A nrPDB Length = 476 Score = 487 bits (1254), Expect = e-138, Method: Compositional matrix adjust. Identities = 232/471 (49%), Positives = 321/471 (68%) Query: 19 LWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFH 78 + +++ + KLPPGPTPLP IGN LQ++ + + S S+ YGPVFT++ G +VV Sbjct: 1 MAKKTSSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 60 Query: 79 GYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGK 138 G++AV+EAL+D EEFSGRG + KG G++ SNG+R K++RRFS+ TLR+FG+GK Sbjct: 61 GHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGK 120 Query: 139 RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM 198 R IE+R+QEEA L++ LR T + DPTF L NVI S+VF RFDYKD+ FL+L+ Sbjct: 121 RGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLL 180 Query: 199 KRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVN 258 + F+ ++ Q+ F ++ PG + + + +I +KV+ +Q +LD N Sbjct: 181 RMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQLLQGLEDFIAKKVEHNQRTLDPN 240 Query: 259 NPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPE 318 +PRDFID FLI+M++E+ N +EF ++NLV T LFV GTET STTLRYG LLL+KHPE Sbjct: 241 SPRDFIDSFLIRMQEEEKNPNTEFYLKNLVMTTLQLFVGGTETVSTTLRYGFLLLMKHPE 300 Query: 319 VTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRN 378 V AKV EEID VIG++R P +DR+ MPY +AV+HEIQR+ D++P + V DTKFR+ Sbjct: 301 VEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRD 360 Query: 379 YLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGE 438 + +PKGT + +L SVL D F NP F+P HFL++ G FKKSD F+PFS GKR C GE Sbjct: 361 FFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGE 420 Query: 439 GLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIP 489 GLARMELFLF TT++QNF LKS K+++ + G ++P +Y + F+P Sbjct: 421 GLARMELFLFFTTVMQNFRLKSSQSPKDIDVSPKHVGFATIPRNYTMSFLP 471 >3TBG-A nrPDB Length = 479 Score = 347 bits (889), Expect = 1e-95, Method: Compositional matrix adjust. Identities = 188/451 (41%), Positives = 268/451 (59%), Gaps = 7/451 (1%) Query: 44 QIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPIS 103 +D ++ F + +G VF++ P+VV +G AV+EAL+ +GE+ + R PI+ Sbjct: 26 HVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPIT 85 Query: 104 QRITKG---LGI-ISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKT 159 Q + G G+ ++ G W+E RRFS++TLRN G+GK+S+E V EEA CL Sbjct: 86 QILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANH 145 Query: 160 KASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNF 219 P P +L A NVI S+ +RF+Y D FL L+ E + + +V N Sbjct: 146 SGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAV 205 Query: 220 PLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLD-VNNPRDFIDCFLIKMEQEKDNQ 278 P+L+ P KVL+ + + E + EH+ + D PRD + FL +ME+ K N Sbjct: 206 PVLLH-IPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNP 264 Query: 279 KSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPC 338 +S FN ENL VADLF AG TTSTTL +GLLL++ HP+V +VQ+EID VIG+ R P Sbjct: 265 ESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPE 324 Query: 339 MQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDD 398 M D++HMPYT AV+HE+QR+ D+VP GV H + D + + + IPKGTT++ L+SVL D+ Sbjct: 325 MGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDE 384 Query: 399 KEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNL 458 + P F P HFLD G+F K + F+PFSAG+R C GE LARMELFLF T++LQ+F+ Sbjct: 385 AVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSF 444 Query: 459 KSVDDLKNLNTTAVTKGIVSLPPSYQICFIP 489 + V +VS P Y++C +P Sbjct: 445 SVPTGQPRPSHHGVFAFLVS-PSPYELCAVP 474 >3DL9-A nrPDB Length = 479 Score = 296 bits (759), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 157/435 (36%), Positives = 254/435 (58%), Gaps = 13/435 (2%) Query: 58 SKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSN- 116 S+VYG +F++ G VV +GY+ VKE L+ E F+ R P+ ++TK G+++S Sbjct: 44 SQVYGEIFSLDLGGISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMGGLLNSRY 103 Query: 117 GKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCN 176 G+ W + RR ++ + R FG G++S E ++ EE + + K P D ++ A N Sbjct: 104 GRGWVDHRRLAVNSFRYFGYGQKSFESKILEETKFFNDAIETYKGRPFDFKQLITNAVSN 163 Query: 177 VICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFP-GTHNKVLK 235 + ++F +RF Y+D +F +++ F+EN + S + + N FP I P G H ++ + Sbjct: 164 ITNLIIFGERFTYEDTDFQHMIELFSENVELAASASVFLYNAFPW-IGILPFGKHQQLFR 222 Query: 236 NVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLF 295 N A+ ++ +++ + P+ F+D +L +M+Q K++ S F+ ENL+ +V +L Sbjct: 223 NAAVVYDFLSRLIEKASVNRKPQLPQHFVDAYLDEMDQGKNDPSSTFSKENLIFSVGELI 282 Query: 296 VAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEI 355 +AGTETT+ LR+ +L + +P + +VQ+EID ++G + P D+ MPYT+AV+HE+ Sbjct: 283 IAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCKMPYTEAVLHEV 342 Query: 356 QRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDK 415 R+ ++VP G+ HA + D R Y IPKGTT++ L SV D+K + +P +F P FLD Sbjct: 343 LRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFLDS 402 Query: 416 NGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNL----KSVDDLKNLNTTA 471 +G F K + +PFS G+R C GE LARME+FLF T +LQ F+L + V DLK Sbjct: 403 SGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHFPHELVPDLKP----- 457 Query: 472 VTKGIVSLPPSYQIC 486 G+ P Y IC Sbjct: 458 -RLGMTLQPQPYLIC 471 >4R20-A nrPDB Length = 486 Score = 249 bits (636), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 148/439 (33%), Positives = 224/439 (51%), Gaps = 8/439 (1%) Query: 54 FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGII 113 FT S YGP+F +Y G + +V V+E L+ G EF+GR + +T+G I Sbjct: 45 FTQLSSQYGPLFGLYAGPHLTLVVSEIGLVREVLLQRGREFAGRPKMVTTDLLTQGGKDI 104 Query: 114 S--SNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILG 171 + WK RR ++ FG G ++ VQE A L EEL+ + D + +L Sbjct: 105 AFADYSPLWKNHRRLVHSSFTLFGEGSNKLQTIVQEAADSLCEELQACRGQSSDLSVVLM 164 Query: 172 CAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHN 231 A NVIC +VF + D T+++ +N+ + + + FP L FP Sbjct: 165 RAVTNVICRLVFSSSYQPSDPELQTVIQ-YNDGI-VQTIARGGLVDIFPWL-RIFPNKDL 221 Query: 232 KVLKN-VALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGT 290 K LK V++ + +K+ EH+ SL PRD +D LI +Q + ++++ T Sbjct: 222 KRLKECVSIRDQLLYKKLLEHKKSLTPGEPRDLLDALLIG-QQRGSGGADDITEDHVLMT 280 Query: 291 VADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDA 350 A+ F AG ETTSTTL + + LL HP++ +VQ E+D +G R PC+ DR H+P DA Sbjct: 281 AAEAFGAGVETTSTTLLWTIAFLLHHPQLQERVQAELDECVGVDRPPCLSDRPHLPLLDA 340 Query: 351 VVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPG 410 V+ E+ R + P +PH DT + +PKGT ++ + ++ HD K + P F+P Sbjct: 341 VLCEVMRIRPVSPILIPHVAMQDTSLGGHSVPKGTRVLVNMWAIHHDPKHWDQPEQFNPE 400 Query: 411 HFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTT 470 FL+ +G K F+PF AG R+C GE LAR+ELFLF++ LQ F+ S +L Sbjct: 401 RFLEPSGKKKTQSSFLPFGAGPRVCVGESLARIELFLFVSRPLQRFSF-SCPSEASLPDL 459 Query: 471 AVTKGIVSLPPSYQICFIP 489 G+V P Y + P Sbjct: 460 QGRFGVVLQPERYTVTVTP 478 >6B82-A nrPDB Length = 509 Score = 236 bits (601), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 140/448 (31%), Positives = 238/448 (53%), Gaps = 29/448 (6%) Query: 30 PPGPTPLPIIGNMLQIDVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEAL 87 PP LPIIG+++ + V D F + K YG ++++ G + +++ + + KE L Sbjct: 25 PPSLPSLPIIGSLMSL-VSDSPPHIFFQDLQKKYGDLYSLMMGSHKLLIVNNHHHAKEIL 83 Query: 88 IDNGEEFSGRGNSPISQRITK-GLGIISSN-GKRWKEIRRFSLTTLRNFGMGKRSIEDRV 145 I G+ F+GR + + +T+ G I ++ WK R+ L FG G SIE + Sbjct: 84 IKKGKIFAGRPRTVTTDLLTRDGKDIAFADYSSTWKFHRKMVHGALCMFGEGSVSIEKII 143 Query: 146 QEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENF 205 EA + E L +++ S D L A NV+C++ F + D F ++++ Sbjct: 144 CREASSMCEVLTESQNSAVDLGPELTRAVTNVVCALCFNSSYKRGDAEFESMLQYSQGIV 203 Query: 206 RILNS-------PWIQVCNNFPLLIDCFPGTHNKVLKN-VALTRSYIREKVKEHQASLDV 257 + PW+Q+ FP ++L+ +++ +++K +EH+ + Sbjct: 204 DTVAKDSLVDIFPWLQI----------FPNKDLRILRQCISIRDKLLQKKYEEHKVTYSD 253 Query: 258 NNPRDFIDCFLIKMEQEKDNQKSEFNI----ENLVGTVADLFVAGTETTSTTLRYGLLLL 313 N RD +D L ++N S ++ ++++ TV ++F AG ETT+TTL++ + L Sbjct: 254 NVQRDLLDALLRAKRSSENNNSSTRDVGLTEDHVLMTVGEIFGAGVETTTTTLKWSIAYL 313 Query: 314 LKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTD 373 + +P+V K+QEE+D IG+ R P + DR ++PY +A + E+ R + P +PH D Sbjct: 314 VHNPQVQRKIQEELDSKIGKERHPQLSDRGNLPYLEATICEVMRIRPVSPLLIPHVALQD 373 Query: 374 TKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFK--KSDYFMPFSAG 431 + Y + KGT ++ + S+ HD+KE+ NP +FDPG FL++ G+ S ++PF AG Sbjct: 374 SSVGEYTVQKGTRVVINMWSLHHDEKEWKNPELFDPGRFLNEEGDGLCCPSGSYLPFGAG 433 Query: 432 KRICAGEGLARMELFLFLTTILQNFNLK 459 R+C GE LA+MELFLFL ILQ F L+ Sbjct: 434 VRVCLGEALAKMELFLFLAWILQRFTLE 461 >6DWN-A nrPDB Length = 491 Score = 229 bits (585), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 147/451 (32%), Positives = 237/451 (52%), Gaps = 22/451 (4%) Query: 21 RQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGY 80 + S + K PPGP P+IG+ML + K+ + + S+ YG V + G P+VV G Sbjct: 4 KTSSKGLKNPPGPWGWPLIGHMLTLG-KNPHLALSRMSQQYGDVLQIRIGSTPVVVLSGL 62 Query: 81 EAVKEALIDNGEEFSGRGNSPISQRITKGLGIISS--NGKRWKEIRRFSLTTLRNFGMGK 138 + +++AL+ G++F GR + I+ G + S +G W RR + L++F + Sbjct: 63 DTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIAS 122 Query: 139 RS-------IEDRVQEEAHCLVEELRKTKASPC--DPTFILGCAPCNVICSVVFQKRFDY 189 +E+ V +EA L+ L++ A P +P + + NVIC++ F +R+D+ Sbjct: 123 DPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYDH 182 Query: 190 KDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALT-RSYIREKV 248 Q L+L+ N ++ S +F ++ P K++ S++++ V Sbjct: 183 NHQELLSLVNLNNNFGEVVGS---GNPADFIPILRYLPNPSLNAFKDLNEKFYSFMQKMV 239 Query: 249 KEHQASLDVNNPRDFIDCFLIKMEQEK---DNQKSEFNIENLVGTVADLFVAGTETTSTT 305 KEH + + + RD D LI+ QEK +N + + E ++ V DLF AG +T +T Sbjct: 240 KEHYKTFEKGHIRDITDS-LIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTA 298 Query: 306 LRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTG 365 + + L+ L+ +P V K+QEE+D VIGR R P + DRSH+PY +A + E R+S VP Sbjct: 299 ISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFT 358 Query: 366 VPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKK--SD 423 +PH+ T DT + + IPKG + + HD K + NP+ F P FL +G K S+ Sbjct: 359 IPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSE 418 Query: 424 YFMPFSAGKRICAGEGLARMELFLFLTTILQ 454 + F GKR C GE +AR E+FLFL +LQ Sbjct: 419 KVIIFGMGKRKCIGETIARWEVFLFLAILLQ 449 >6IQ5-A nrPDB Length = 463 Score = 225 bits (574), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 140/429 (32%), Positives = 221/429 (51%), Gaps = 27/429 (6%) Query: 53 SFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGI 112 SF ++ YG VF + G PIVV +G A+ +AL+ G F+ R + + ++ G + Sbjct: 6 SFARLARRYGDVFQIRLGSCPIVVLNGERAIHQALVQQGSAFADRPSFASFRVVSGGRSM 65 Query: 113 ISSN-GKRWKEIRRFSLTTLRNF----GMGKRSIEDRVQEEAHCLVEELRKTKASPC--D 165 + + WK RR + + +RNF ++ +E V EA LV L + A D Sbjct: 66 AFGHYSEHWKVQRRAAHSMMRNFFTRQPRSRQVLEGHVLSEARELVALLVRGSADGAFLD 125 Query: 166 PTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNS-------PWIQVCNN 218 P + A NV+ +V F R+ + D F L+ E R + + PW+Q Sbjct: 126 PRPLTVVAVANVMSAVCFGCRYSHDDPEFRELLSHNEEFGRTVGAGSLVDVMPWLQY--- 182 Query: 219 FPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNN-PRDFIDCFLIKMEQEKDN 277 FP + ++ +N + ++I +K H SL PRD +D F++ E++ Sbjct: 183 FPNPVRTVFREFEQLNRNFS---NFILDKFLRHCESLRPGAAPRDMMDAFILSAEKKAAG 239 Query: 278 QK----SEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGR 333 + ++EN+ T+ D+F A +T ST L++ LLL ++P+V +VQ E+D V+GR Sbjct: 240 DSHGGGARLDLENVPATITDIFGASQDTLSTALQWLLLLFTRYPDVQTRVQAELDQVVGR 299 Query: 334 HRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTS 393 R PCM D+ ++PY A ++E R+S VP +PHA T +T Y IPK T + S Sbjct: 300 DRLPCMGDQPNLPYVLAFLYEAMRFSSFVPVTIPHATTANTSVLGYHIPKDTVVFVNQWS 359 Query: 394 VLHDDKEFPNPNIFDPGHFLDKNGNFKK--SDYFMPFSAGKRICAGEGLARMELFLFLTT 451 V HD ++PNP FDP FLDK+G K + M FS GKR C GE L++M+LFLF++ Sbjct: 360 VNHDPVKWPNPENFDPARFLDKDGLINKDLTSRVMIFSVGKRRCIGEELSKMQLFLFISI 419 Query: 452 ILQNFNLKS 460 + + ++ Sbjct: 420 LAHQCDFRA 428 >4R1Z-A nrPDB Length = 439 Score = 217 bits (552), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 128/407 (31%), Positives = 213/407 (52%), Gaps = 26/407 (6%) Query: 69 FGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITK-GLGIISSN-GKRWKEIRRF 126 G + +++ + + KE LI G+ F+GR + + +T+ G I ++ WK R+ Sbjct: 1 MGSHKLLIVNNHHHAKEILIKKGKIFAGRPRTVTTDLLTRDGKDIAFADYSSTWKFHRKM 60 Query: 127 SLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKR 186 L FG G SIE + EA + E L +++ S D L A NV+C++ F Sbjct: 61 VHGALCMFGEGSVSIEKIICREASSMCEVLTESQNSAVDLGPELTRAVTNVVCALCFNSS 120 Query: 187 FDYKDQNFLTLMKRFNENFRILNS-------PWIQVCNNFPLLIDCFPGTHNKVLKN-VA 238 + D F ++++ + PW+Q+ FP +L+ ++ Sbjct: 121 YKRGDAEFESMLQYSQGIVDTVAKDSLVDIFPWLQI----------FPNKDLTILRQCIS 170 Query: 239 LTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNI----ENLVGTVADL 294 + +++K +EH+ + N RD +D L ++N S ++ ++++ TV D+ Sbjct: 171 IRDKLLQKKYEEHKVTYSDNVQRDLLDALLRAKRSSENNNSSTRDVGLTEDHVLMTVGDI 230 Query: 295 FVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHE 354 F AG ETT+T L++ + L+ +P+V K+QEE+D IG+ R P + DR ++PY +A + E Sbjct: 231 FGAGVETTTTVLKWSIAYLVHNPQVQRKIQEELDSKIGKERHPQLSDRGNLPYLEATIRE 290 Query: 355 IQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLD 414 + R + P +PH D+ Y + KGT ++ L S+ HD KE+ NP +FDPG FL+ Sbjct: 291 VLRIRPVSPLLIPHVALQDSSVGEYTVQKGTRVVINLWSLHHDKKEWKNPELFDPGRFLN 350 Query: 415 KNGNFK--KSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLK 459 + G+ S ++PF AG R+C GE LA+MELFLFL ILQ F L+ Sbjct: 351 EEGDGLCCPSGSYLPFGAGVRVCLGEALAKMELFLFLAWILQRFTLE 397 >2HI4-A nrPDB Length = 495 Score = 204 bits (519), Expect = 7e-53, Method: Compositional matrix adjust. Identities = 137/457 (29%), Positives = 220/457 (48%), Gaps = 41/457 (8%) Query: 28 KLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEAL 87 K PP P P++G++L + K+ + + S+ YG V + G P++V + +++AL Sbjct: 16 KSPPEPWGWPLLGHVLTLG-KNPHLALSRMSQRYGDVLQIRIGSTPVLVLSRLDTIRQAL 74 Query: 88 IDNGEEFSGRGNSPISQRITKG--LGIISSNGKRWKEIRRFSLTTLRNFGMGKRS----- 140 + G++F GR + S IT G L + +G W RR + L F + Sbjct: 75 VRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIASDPASSSS 134 Query: 141 --IEDRVQEEAHCLVEELRKTKASPC--DPTFILGCAPCNVICSVVFQKRFDYKDQNFLT 196 +E+ V +EA L+ L++ A P DP + + NVI ++ F + F L+ Sbjct: 135 CYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANVIGAMCFGQHFPESSDEMLS 194 Query: 197 LMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTR---------SYIREK 247 L+K +E +S + FP+L + L N AL R ++++ Sbjct: 195 LVKNTHEFVETASSG--NPLDFFPIL---------RYLPNPALQRFKAFNQRFLWFLQKT 243 Query: 248 VKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNI---ENLVGTVADLFVAGTETTST 304 V+EH D N+ RD + K ++ N+ E +V V D+F AG +T +T Sbjct: 244 VQEHYQDFDKNSVRDITGALF---KHSKKGPRASGNLIPQEKIVNLVNDIFGAGFDTVTT 300 Query: 305 TLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPT 364 + + L+ L+ PE+ K+Q+E+D VIGR R P + DR +PY +A + E R+S +P Sbjct: 301 AISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHSSFLPF 360 Query: 365 GVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNG---NFKK 421 +PH+ T DT + IPK + V HD + + +P+ F P FL +G N Sbjct: 361 TIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTAINKPL 420 Query: 422 SDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNL 458 S+ M F GKR C GE LA+ E+FLFL +LQ Sbjct: 421 SEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEF 457 >5UYS-A nrPDB Length = 494 Score = 189 bits (481), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 132/449 (29%), Positives = 221/449 (49%), Gaps = 17/449 (3%) Query: 28 KLPPGPTPLPIIGNMLQIDVK-DICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEA 86 K P LP++G++ + + +F K YGP+++V G V+ ++ KE Sbjct: 8 KYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEV 67 Query: 87 LIDNGEEFSGR---GNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIED 143 LI G++FSGR I+ KG+ S G W+ RR ++ T F G + +E Sbjct: 68 LIKKGKDFSGRPQMATLDIASNNRKGIAFADS-GAHWQLHRRLAMATFALFKDGDQKLEK 126 Query: 144 RVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNE 203 + +E L + L D +F + A NVI + F + D L +++ +NE Sbjct: 127 IICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPE-LNVIQNYNE 185 Query: 204 NFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKE-HQASLDVNNPRD 262 I N + + P L FP + LK+ R+ + K+ E ++ ++ + Sbjct: 186 GI-IDNLSKDSLVDLVPWL-KIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDSITN 243 Query: 263 FIDCFL-IKMEQEKDN----QKSEFNIEN-LVGTVADLFVAGTETTSTTLRYGLLLLLKH 316 +D + KM + N Q SE +N ++ T+ D+F AG ETT++ +++ L LL + Sbjct: 244 MLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHN 303 Query: 317 PEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKF 376 P+V K+ EEID +G R+P + DR+ + +A + E+ R + P +PH D+ Sbjct: 304 PQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSI 363 Query: 377 RNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGN--FKKSDYFMPFSAGKRI 434 + + KGT ++ L ++ H++KE+ P+ F P FL+ G S ++PF AG R Sbjct: 364 GEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRS 423 Query: 435 CAGEGLARMELFLFLTTILQNFNLKSVDD 463 C GE LAR ELFL + +LQ F+L+ DD Sbjct: 424 CIGEILARQELFLIMAWLLQRFDLEVPDD 452 >5VBU-A nrPDB Length = 476 Score = 184 bits (467), Expect = 8e-47, Method: Compositional matrix adjust. Identities = 132/479 (27%), Positives = 226/479 (47%), Gaps = 27/479 (5%) Query: 21 RQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGY 80 +++ + KLPP + L + D+ ++ +GP++ ++ G+ +VV + Sbjct: 3 KKTSSKGKLPP------LAPGFLHLLQPDLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSK 56 Query: 81 EAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKR--WKEIRRFSLTTLRNFGMGK 138 ++EA++ +F+GR + +++ +S WK ++ + + L +G Sbjct: 57 RTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLSLGDYSLLWKAHKKLTRSALL---LGI 113 Query: 139 R-SIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTL 197 R S+E V++ E +R +P C++IC + F + KD N + Sbjct: 114 RDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTCSIICYLTFGDKI--KDDNLMPA 171 Query: 198 MKRFNENFRILNSPW-IQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIRE-KVKEHQASL 255 + + S W IQ+ + P L FP + LK R +I E ++++H+ SL Sbjct: 172 YYKCIQEVLKTWSHWSIQIVDVIPFL-RFFPNPGLRRLKQAIEKRDHIVEMQLRQHKESL 230 Query: 256 DVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVA-DLFVAGTETTSTTLRYGLLLLL 314 RD +D L + Q + S +E V A DL + GTETT+ TL + ++ LL Sbjct: 231 VAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLSWAVVFLL 290 Query: 315 KHPEVTAKVQEEIDHVIGRHRSPC---MQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVT 371 HPE+ ++QEE+DH +G S +DR+ +P +A + E+ R +VP +PH T Sbjct: 291 HHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTT 350 Query: 372 TDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAG 431 + Y IP+GT I+ L D+ + P+ F P FL+ N + + F G Sbjct: 351 RPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSRA----LAFGCG 406 Query: 432 KRICAGEGLARMELFLFLTTILQNFN-LKSVDDLKNLNTTAVTKGIVSLPPSYQICFIP 489 R+C GE LAR+ELF+ LT +LQ F L S D L +L I+ + P +Q+ P Sbjct: 407 ARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALPSLQPLPHCSVILKMQP-FQVRLQP 464 >3QZ1-A nrPDB Length = 496 Score = 172 bits (436), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 125/438 (28%), Positives = 206/438 (47%), Gaps = 35/438 (7%) Query: 37 PIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSG 96 P++ L + ++ + ++ GPV+ + G+ +VV + ++EA+I +F+G Sbjct: 32 PLVPGFLHLLQPNLPIHLLSLTQKLGPVYRLRLGLQEVVVLNSKRTIEEAMIRKWVDFAG 91 Query: 97 RGNSP----ISQRITK-GLGIISSNGKRWKEIRRFSLTTLRNFGMGKRS-IEDRVQEEAH 150 R P +SQR LG S K K++ R +L +G RS +E V + Sbjct: 92 RPQIPSYKLVSQRCQDISLGDYSLLWKAHKKLTRSALL------LGTRSSMEPWVDQLTQ 145 Query: 151 CLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNS 210 E +R +P C++IC + F + D TL+ F++ + L Sbjct: 146 EFCERMRVQAGAPVTIQKEFSLLTCSIICYLTFGNKED-------TLVHAFHDCVQDLMK 198 Query: 211 PW----IQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREK-VKEHQASLDVNNPRDFID 265 W IQ+ + P L FP LK R ++ EK ++ H+ S+ RD D Sbjct: 199 TWDHWSIQILDMVPFL-RFFPNPGLWRLKQAIENRDHMVEKQLRRHKESMVAGQWRDMTD 257 Query: 266 CFLIKMEQEKDNQKSEFNIENLVG-TVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQ 324 L + +++ + +E V +V DLF+ GTETT++TL + + LL HPE+ ++Q Sbjct: 258 YMLQGVGRQRVEEGPGQLLEGHVHMSVVDLFIGGTETTASTLSWAVAFLLHHPEIQRRLQ 317 Query: 325 EEIDHVIGRHRSPC----MQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYL 380 EE+D +G S C +DR+ +P +A + E+ R +VP +PH T + Y Sbjct: 318 EELDRELGPGAS-CSRVTYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSIFGYD 376 Query: 381 IPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGL 440 IP+G ++ L D+ + P+ F P FL+ N + F G R+C GE L Sbjct: 377 IPEGMVVIPNLQGAHLDETVWEQPHEFRPDRFLEPGANPSA----LAFGCGARVCLGESL 432 Query: 441 ARMELFLFLTTILQNFNL 458 AR+ELF+ L +LQ F L Sbjct: 433 ARLELFVVLARLLQAFTL 450 >5YLW-A nrPDB Length = 495 Score = 160 bits (404), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 127/486 (26%), Positives = 224/486 (46%), Gaps = 50/486 (10%) Query: 3 PFVVLVLCLSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYG 62 P + + ++ + F +R RRR LPPGP P PI+GNMLQ+ + + F SK YG Sbjct: 5 PLLAALFFIAATITFLSFR---RRRNLPPGPFPYPIVGNMLQLGA-NPHQVFAKLSKRYG 60 Query: 63 PVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQ--------RITKGLGIIS 114 P+ +++ G V+ E KE L +G+ FSGR I+Q +I+ G ++ Sbjct: 61 PLMSIHLGSLYTVIVSSPEMAKEILHRHGQVFSGRT---IAQAVHACDHDKISMGFLPVA 117 Query: 115 SNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKAS--PCDPTFILGC 172 S W+++R+ + + + + +++ L++ ++K S D Sbjct: 118 SE---WRDMRKICKEQMFS-NQSMEASQGLRRQKLQQLLDHVQKCSDSGRAVDIREAAFI 173 Query: 173 APCNVICSVVFQKRFDYKDQNFLTLMKRFNENFR-ILNSPWIQVCNNFPLL--------- 222 N++ + +F + D K E I+ P + FP+L Sbjct: 174 TTLNLMSATLFSSQATEFDSKATMEFKEIIEGVATIVGVP--NFADYFPILRPFDPQGVK 231 Query: 223 --IDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKS 280 D F G K +A Y+ E+++ +A+ + DF++ + + Q + Sbjct: 232 RRADVFFG------KLLAKIEGYLNERLESKRANPNAPKKDDFLEIVVDII------QAN 279 Query: 281 EFNIE--NLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPC 338 EF ++ + + DLFV G++T +T++ + + L+ +P+ A+++ E+ V G + Sbjct: 280 EFKLKTHHFTHLMLDLFVGGSDTNTTSIEWAMSELVMNPDKMARLKAELKSVAGDEKIVD 339 Query: 339 MQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDD 398 +PY AV+ E+ R P +P +D + YLIPKGT I+ ++ D Sbjct: 340 ESAMPKLPYLQAVIKEVMRIHPPGPLLLPRKAESDQEVNGYLIPKGTQILINAYAIGRDP 399 Query: 399 KEFPNPNIFDPGHFLDKNGNFKKSDY-FMPFSAGKRICAGEGLARMELFLFLTTILQNFN 457 + +P FDP FLD +FK DY +PF +G+R+C G LA L + T++ NF+ Sbjct: 400 SIWTDPETFDPERFLDNKIDFKGQDYELLPFGSGRRVCPGMPLATRILHMATATLVHNFD 459 Query: 458 LKSVDD 463 K DD Sbjct: 460 WKLEDD 465 >6DA2-A nrPDB Length = 487 Score = 121 bits (303), Expect = 8e-28, Method: Compositional matrix adjust. Identities = 118/443 (26%), Positives = 184/443 (41%), Gaps = 29/443 (6%) Query: 31 PGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDN 90 PGPTPLP +GN+L K C K YG V+ Y G P++ + +K L+ Sbjct: 19 PGPTPLPFLGNILSYH-KGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKE 77 Query: 91 GEE-FSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGK-RSIEDRVQEE 148 F+ R P I + + WK +R T F GK + + + + Sbjct: 78 CYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLSPT---FTSGKLKEMVPIIAQY 132 Query: 149 AHCLVEELRKTKAS--PCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFR 206 LV LR+ + P + G +VI S F D + ++ + R Sbjct: 133 GDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLR 192 Query: 207 I-LNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTR---SYIREKVKEHQASLDVNNPRD 262 P+ FP LI +VL R +++R+ VK + S + + Sbjct: 193 FDFLDPFFLSITVFPFLIPIL-----EVLNICVFPREVTNFLRKSVKRMKESRLEDTQKH 247 Query: 263 FIDCFLIKME----QEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPE 318 +D + ++ +E ++ K+ ++E + ++ +F AG ETTS+ L + + L HP+ Sbjct: 248 RVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIF-AGYETTSSVLSFIMYELATHPD 306 Query: 319 VTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTG--VPHAVTTDTKF 376 V K+QEEID V+ P M Y D VV+E R L P + D + Sbjct: 307 VQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLR---LFPIAMRLERVCKKDVEI 363 Query: 377 RNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICA 436 IPKG +M ++ D K + P F P F KN + + PF +G R C Sbjct: 364 NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCI 423 Query: 437 GEGLARMELFLFLTTILQNFNLK 459 G A M + L L +LQNF+ K Sbjct: 424 GMRFALMNMKLALIRVLQNFSFK 446 >5VEU-A nrPDB Length = 480 Score = 116 bits (291), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 125/467 (26%), Positives = 198/467 (42%), Gaps = 44/467 (9%) Query: 14 MLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNP 73 M L+ +R PGPTPLP++GN+L + + K T K YG ++ Y G P Sbjct: 1 MALYGTRTHGLFKRLGIPGPTPLPLLGNVLSYR-QGLWKFDTECYKKYGKMWGTYEGQLP 59 Query: 74 IVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISS-----NGKRWKEIRRFSL 128 ++ + ++ L+ E +S N +R +G + S + WK IR Sbjct: 60 VLAITDPDVIRTVLVK--ECYSVFTN----RRSLGPVGFMKSAISLAEDEEWKRIRSLLS 113 Query: 129 TTLRNFGMGK-RSIEDRVQEEAHCLVEELRKT--KASPCDPTFILGCAPCNVICSVVFQK 185 T F GK + + + + LV LR+ K P I G +VI F Sbjct: 114 PT---FTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGV 170 Query: 186 RFDY---KDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVAL--- 239 D F+ K+F + F L+ ++ + FP L F NV+L Sbjct: 171 NIDSLNNPQDPFVESTKKFLK-FGFLDPLFLSIIL-FPFLTPVFEAL------NVSLFPK 222 Query: 240 -TRSYIREKVKEHQASLDVNNPRDFIDCFLIKME----QEKDNQKSEFNIENLVGTVADL 294 T +++ + V + S + + +D + ++ +E ++ K+ ++E ++ + Sbjct: 223 DTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSKETESHKALSDLELAAQSIIFI 282 Query: 295 FVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHE 354 F AG ETTS+ L + L L HP+V K+Q+EID V+ P M Y D VV+E Sbjct: 283 F-AGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNE 341 Query: 355 IQRYSDLVPTGV--PHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHF 412 R L P + D + IPKG+ ++ ++ HD K + P F P F Sbjct: 342 TLR---LFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERF 398 Query: 413 LDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLK 459 K + Y PF G R C G A M + L L +LQNF+ K Sbjct: 399 SKKKDSIDPYIY-TPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFK 444 >3K9V-A nrPDB Length = 482 Score = 99.0 bits (245), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 114/471 (24%), Positives = 202/471 (42%), Gaps = 77/471 (16%) Query: 31 PGPTPLPIIGNMLQIDVKDICK----SFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEA 86 PGPT P++G++L+I K K + + K YG +F + G V G ++ EA Sbjct: 27 PGPTNWPLLGSLLEIFWKGGLKKQHDTLAEYHKKYGQIFRMKLGSFDSVHL-GSPSLLEA 85 Query: 87 LIDNGEEFSGRGNSPISQRI------------TKGLGIISSNGKRWKEIRR-FSLTTLRN 133 L R S QR+ + G++ G+ W+ +R F ++ Sbjct: 86 LY--------RTESAHPQRLEIKPWKAYRDHRNEAYGLMILEGQEWQRVRSAFQKKLMKP 137 Query: 134 FGMGKRSIEDRVQEEAHCLVE---ELRKTKASPCDPTFILGCAPCNVICSVVFQKRF--- 187 + K ++ ++ E +E EL + D L IC V+++KRF Sbjct: 138 VEIMK--LDKKINEVLADFLERMDELCDERGRIPDLYSELNKWSFESICLVLYEKRFGLL 195 Query: 188 ----DYKDQNFLTLMKRFNENF-RILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRS 242 + + F+T +K F +++ +P ++ + KV + L Sbjct: 196 QKETEEEALTFITAIKTMMSTFGKMMVTP-----------VELHKRLNTKVWQAHTLAWD 244 Query: 243 YIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDN-------QKSEFNIENLVGTVADLF 295 I + VK ID L + Q+ Q+ + + L V +L Sbjct: 245 TIFKSVK------------PCIDNRLQRYSQQPGADFLCDIYQQDHLSKKELYAAVTELQ 292 Query: 296 VAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEI 355 +A ETT+ +L + L L ++P+ ++ +E+ V+ +++P +D +MPY A + E Sbjct: 293 LAAVETTANSLMWILYNLSRNPQAQRRLLQEVQSVLPDNQTPRAEDLRNMPYLKACLKES 352 Query: 356 QRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKE-FPNPNIFDPGHFLD 414 R + VP + T Y +PKGT ++ L T VL ++ F + + F P +L Sbjct: 353 MRLTPSVPFTT-RTLDKPTVLGEYALPKGT-VLTLNTQVLGSSEDNFEDSHKFRPERWLQ 410 Query: 415 KNGNFKKSDYF--MPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDD 463 K KK + F +PF GKR+C G LA ++L L L I+Q +++ + D+ Sbjct: 411 KE---KKINPFAHLPFGIGKRMCIGRRLAELQLHLALCWIIQKYDIVATDN 458 >3MDV-A nrPDB Length = 456 Score = 92.4 bits (228), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 102/426 (23%), Positives = 174/426 (40%), Gaps = 44/426 (10%) Query: 54 FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALID---NGEEFSGRGNSPISQRITKGL 110 F +++K YGPV V V+ E+VK+ L+ N + R + G Sbjct: 16 FLDWAKKYGPVVRVNVFHKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFGQ 75 Query: 111 GIISS-NGKRWKEIRR-----FSLTTLRNFGMGKRSIEDRVQEEAHCLVE--ELRKTKAS 162 G++S N +RW + RR FS ++L S+ + E+A LVE E + + Sbjct: 76 GLVSECNYERWHKQRRVIDLAFSRSSLV-------SLMETFNEKAEQLVEILEAKADGQT 128 Query: 163 PCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLL 222 P +L +++ F + L K ++ +++ N L Sbjct: 129 PVSMQDMLTYTAMDILAKAAF----GMETSMLLGAQKPLSQAVKLMLEGITASRNT---L 181 Query: 223 IDCFPGTHNK---VLKNVALTRSYIREKVKEHQASLDVNN--PRDFIDCFLIKMEQEKDN 277 PG + V +++ R R+ V+ + +L P D + L E +D+ Sbjct: 182 AKFLPGKRKQLREVRESIRFLRQVGRDWVQRRREALKRGEEVPADILTQILKAEEGAQDD 241 Query: 278 QKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSP 337 E L+ F+AG ET++ L + ++ L + PE+ A++Q E+D VIG R Sbjct: 242 -------EGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYL 294 Query: 338 CMQDRSHMPYTDAVVHEIQRYSDLVP--TGVPHAVTTDTKFRNYLIPKGTTIMALLTSVL 395 +D + Y V+ E R L P G + +T +P T ++ + Sbjct: 295 DFEDLGRLQYLSQVLKESLR---LYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMG 351 Query: 396 HDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQN 455 D F +P F+P F G K + PFS G R C G+ A+ME+ + + +LQ Sbjct: 352 RMDTYFEDPLTFNPDRF--GPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQR 409 Query: 456 FNLKSV 461 + V Sbjct: 410 LEFRLV 415 >2VE3-A nrPDB Length = 444 Score = 80.1 bits (196), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 98/434 (22%), Positives = 175/434 (40%), Gaps = 38/434 (8%) Query: 29 LPPGPTPLPIIGNMLQ-IDVKDICKSFTNFSKVYGPVF-TVYFGMNPIVVFHGYEAVKEA 86 +PPG LP +G L ++ D K + +GP+F T FG N I + A+ Sbjct: 13 IPPGDFGLPWLGETLNFLNDGDFGK---KRQQQFGPIFKTRLFGKNVIFI---SGALANR 66 Query: 87 LIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQ 146 + E+ + + P+S RI G +++ RR L R++ D Sbjct: 67 FLFTKEQETFQATWPLSTRILLGPNALATQMGEIHRSRRKILYQ----AFLPRTL-DSYL 121 Query: 147 EEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFR 206 + +V+ ++ N + +R + L + ++ ++N + Sbjct: 122 PKMDGIVQ------------GYLEQWGKANEVIWYPQLRRMTFDVAATLFMGEKVSQNPQ 169 Query: 207 ILNSPWIQ--VCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFI 264 + PW + + F L I K + AL + + + +K Q P Sbjct: 170 LF--PWFETYIQGLFSLPIPLPNTLFGKSQRARALLLAELEKIIKARQ-----QQPPSEE 222 Query: 265 DCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQ 324 D I + DN + ++ L + L AG ET ++ L LLL +H ++ +V+ Sbjct: 223 DALGILLAARDDNNQP-LSLPELKDQILLLLFAGHETLTSALSSFCLLLGQHSDIRERVR 281 Query: 325 EEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKG 384 +E + + + + MPY D V+ E+ R V G + D +F+ + PKG Sbjct: 282 QE-QNKLQLSQELTAETLKKMPYLDQVLQEVLRLIPPVGGGF-RELIQDCQFQGFHFPKG 339 Query: 385 TTIMALLTSVLHDDKEFPNPNIFDPGHFL-DKNGNFKKSDYFMPFSAGKRICAGEGLARM 443 + ++ D +P+P FDP F D + +PF G R C G+ AR+ Sbjct: 340 WLVSYQISQTHADPDLYPDPEKFDPERFTPDGSATHNPPFAHVPFGGGLRECLGKEFARL 399 Query: 444 ELFLFLTTILQNFN 457 E+ LF T ++Q F+ Sbjct: 400 EMKLFATRLIQQFD 413 >3S79-A nrPDB Length = 503 Score = 77.8 bits (190), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 57/197 (28%), Positives = 97/197 (49%), Gaps = 7/197 (3%) Query: 265 DCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQ 324 +C E ++ + EN+ + ++ +A +T S +L + L L+ KHP V + Sbjct: 274 ECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAII 333 Query: 325 EEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKG 384 +EI VIG R + D + + ++E RY +V + A+ D Y + KG Sbjct: 334 KEIQTVIG-ERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDV-IDGYPVKKG 391 Query: 385 TTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARME 444 T I+ L +H + FP PN F +F KN ++ YF PF G R CAG+ +A + Sbjct: 392 TNII-LNIGRMHRLEFFPKPNEFTLENF-AKNVPYR---YFQPFGFGPRGCAGKYIAMVM 446 Query: 445 LFLFLTTILQNFNLKSV 461 + L T+L+ F++K++ Sbjct: 447 MKAILVTLLRRFHVKTL 463 >3EL3-A nrPDB Length = 467 Score = 73.9 bits (180), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 84/360 (23%), Positives = 143/360 (39%), Gaps = 35/360 (9%) Query: 111 GIISSNGKRWKEIRR-----FSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCD 165 G+ ++NG + RR F L + +G ++EEAH L E + K Sbjct: 103 GVATANGPLHRRQRRTIQPAFRLDAIPAYG-------PIMEEEAHALTERWQPGKTVDAT 155 Query: 166 PTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDC 225 C + Q + ++ + L F +R + P PL Sbjct: 156 SESFRVAVRVAARCLLRGQYMDERAERLCVALATVFRGMYRRMVVPL------GPLYRLP 209 Query: 226 FPGTH--NKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFN 283 P N L ++ L + E + E +AS P D + L + KD+ Sbjct: 210 LPANRRFNDALADLHL---LVDEIIAERRAS--GQKPDDLLTALL----EAKDDNGDPIG 260 Query: 284 IENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRS 343 + + V + G+ET ++T+ + L L HPE ++++E++ V G R +D Sbjct: 261 EQEIHDQVVAILTPGSETIASTIMWLLQALADHPEHADRIRDEVEAVTG-GRPVAFEDVR 319 Query: 344 HMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPN 403 + +T V+ E R V AV +++ Y IP G I+ ++ D K + + Sbjct: 320 KLRHTGNVIVEAMRLRPAVWVLTRRAVA-ESELGGYRIPAGADIIYSPYAIQRDPKSYDD 378 Query: 404 PNIFDPGHFL-DKNGNFKKSDYFM-PFSAGKRICAGEGLARMELFLFLTTILQNFNLKSV 461 FDP +L ++ N K Y M PFSAGKR C + + +L L + + + V Sbjct: 379 NLEFDPDRWLPERAANVPK--YAMKPFSAGKRKCPSDHFSMAQLTLITAALATKYRFEQV 436 >3N9Z-A nrPDB Length = 487 Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 52/207 (25%), Positives = 102/207 (49%), Gaps = 18/207 (8%) Query: 280 SEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCM 339 S+ + E++ V ++ G +TTS TL++ L + ++ +V ++ E+ + RH++ Sbjct: 269 SKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEV--LAARHQAQG- 325 Query: 340 QDRSHM----PYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVL 395 D + M P A + E R + T + + D R+Y+IP T + + ++ Sbjct: 326 -DMATMLQLVPLLKASIKETLRLHPISVT-LQRYLVNDLVLRDYMIPAKTLVQVAIYALG 383 Query: 396 HDDKEFPNPNIFDPGHFLDKNGNFKKSDYF--MPFSAGKRICAGEGLARMELFLFLTTIL 453 + F +P FDP +L K+ N YF + F G R C G +A +E+ +FL +L Sbjct: 384 REPTFFFDPENFDPTRWLSKDKNIT---YFRNLGFGWGVRQCLGRRIAELEMTIFLINML 440 Query: 454 QNFNLKSVDDLKNLNTTAVTKGIVSLP 480 +NF + ++++L+ T ++ +P Sbjct: 441 ENFRV----EIQHLSDVGTTFNLILMP 463 >6C94-A nrPDB Length = 497 Score = 70.1 bits (170), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 58/231 (25%), Positives = 101/231 (43%), Gaps = 12/231 (5%) Query: 235 KNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADL 294 + AL REK++ + DF+D L+ + E Q S+ ++ V T Sbjct: 242 RKAALQDEKEREKIQNRRH-------LDFLD-ILLDVRGESGVQLSDTDLRAEVDT---F 290 Query: 295 FVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHE 354 G +TT++ + + L + +PE + +EE+ ++G S +D + M Y + E Sbjct: 291 MFEGHDTTTSGISWFLYCMALYPEHQQRCREEVREILGDQDSFQWEDLAKMTYLTMCMKE 350 Query: 355 IQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLD 414 R VP + +P G+ I + ++ + +P+P +FDP F Sbjct: 351 CFRLYPPVPQVYRQLSKPVSFVDGRSLPAGSLISLHIYALHRNSDVWPDPEVFDPLRFSP 410 Query: 415 KNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLK 465 +N + + F+PFSAG R C G+ A E+ + L F SVD L+ Sbjct: 411 ENSSGRHPYAFIPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEF-SVDPLR 460 >6AYB-A nrPDB Length = 466 Score = 69.3 bits (168), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 54/232 (23%), Positives = 109/232 (46%), Gaps = 7/232 (3%) Query: 245 REKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTST 304 RE+ K+H L + D +D L ++ KD Q E + +G + AG T+S Sbjct: 220 REEHKKHPERLLDESKMDVVDHLLT--QKYKDGQ--ELTDVHRIGILIAGLFAGQHTSSI 275 Query: 305 TLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQR-YSDLVP 363 T + L+ ++ + +V KV++E + ++G + M Y +A + E R Y L+ Sbjct: 276 TSSWTLMNVISNKKVLEKVRKEQEEIMGSDKVLDYDKVMKMDYLEACMKEALRMYPPLI- 334 Query: 364 TGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSD 423 + + Y+IPKG ++ + + NP++FDP ++ + K Sbjct: 335 -MIMRMARKPRECEQYIIPKGNILVVSPSVAGRCTDTYTNPDVFDPERLTERKEHEKFKY 393 Query: 424 YFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKG 475 +PF AG+ C GE A +++ ++ +L+ F+++ + + + + T++ G Sbjct: 394 GAVPFGAGRHKCIGENFALLQVKSIISILLRYFDMEYIGKIPDPSYTSLVVG 445 >3MZS-A nrPDB Length = 486 Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 50/195 (25%), Positives = 91/195 (46%), Gaps = 13/195 (6%) Query: 284 IENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRS 343 +E++ + ++ G TTS TL++ L + + V ++EE+ + + + Sbjct: 274 LEDVKANITEMLAGGVNTTSMTLQWHLYEMARSLNVQEMLREEVLNARRQAEGDISKMLQ 333 Query: 344 HMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPN 403 +P A + E R + T + +D ++YLIP T + + ++ D F + Sbjct: 334 MVPLLKASIKETLRLHPISVT-LQRYPESDLVLQDYLIPAKTLVQVAIYAMGRDPAFFSS 392 Query: 404 PNIFDPGHFLDKNGN---FKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLK- 459 P+ FDP +L K+ + F+ + F G R C G +A +E+ LFL IL+NF ++ Sbjct: 393 PDKFDPTRWLSKDKDLIHFRN----LGFGWGVRQCVGRRIAELEMTLFLIHILENFKVEM 448 Query: 460 ----SVDDLKNLNTT 470 VD + NL T Sbjct: 449 QHIGDVDTIFNLILT 463 >4KPA-A nrPDB Length = 494 Score = 66.2 bits (160), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 57/199 (28%), Positives = 85/199 (42%), Gaps = 7/199 (3%) Query: 265 DCFLIKMEQEKDNQKSE-FNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKV 323 D L M KD + E + EN+ + +AG ETTS L + L L+K+P V K Sbjct: 255 DDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKA 314 Query: 324 QEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPK 383 EE V+ P + + Y V++E R P +A Y + K Sbjct: 315 AEEAARVL-VDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEK 373 Query: 384 GTTIMALLTSVLHDDKEFPNPNI--FDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLA 441 G +M L+ LH DK ++ F P F +N + F PF G+R C G+ A Sbjct: 374 GDELMVLIPQ-LHRDKTIWGDDVEEFRPERF--ENPSAIPQHAFKPFGNGQRACIGQQFA 430 Query: 442 RMELFLFLTTILQNFNLKS 460 E L L +L++F+ + Sbjct: 431 LHEATLVLGMMLKHFDFED 449 >2WX2-A nrPDB Length = 473 Score = 64.7 bits (156), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 57/236 (24%), Positives = 106/236 (44%), Gaps = 25/236 (10%) Query: 231 NKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGT 290 K+L + + R ++ +AS D NN D + L + ++ + ++ + G Sbjct: 223 QKILGEIIVAR-------EKEEASKD-NNTSDLLGGLLKAVYRDG----TRMSLHEVCGM 270 Query: 291 VADLFVAGTETTSTTLRYGLLLLL--KHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYT 348 + AG T++ T + +L L+ K+ + K+ +EID + + D MP+ Sbjct: 271 IVAAMFAGQHTSTITTSWSMLHLMHPKNKKWLDKLHKEIDEFPAQLNYDNVMD--EMPFA 328 Query: 349 DAVVHE-IQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIF 407 + V E I+R L+ V V + K +Y++PKG I HD++ FPNP ++ Sbjct: 329 ERCVRESIRRDPPLL--MVMRMVKAEVKVGSYVVPKGDIIACSPLLSHHDEEAFPNPRLW 386 Query: 408 DPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDD 463 DP + K F+ F AG C G+ A +++ L T + ++ + + D Sbjct: 387 DP------ERDEKVDGAFIGFGAGVHKCIGQKFALLQVKTILATAFREYDFQLLRD 436 >4ZGX-A nrPDB Length = 489 Score = 62.0 bits (149), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 42/161 (26%), Positives = 74/161 (45%), Gaps = 6/161 (3%) Query: 279 KSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPC 338 K+E ++E + +L +TT+ L L L ++P+V +++E Sbjct: 273 KAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHP 332 Query: 339 MQDRSHMPYTDAVVHEIQRYSDLVPTGV--PHAVTTDTKFRNYLIPKGTTIMALLTSVLH 396 + + +P A + E R L P G+ V++D +NY IP GT + L S+ Sbjct: 333 QKATTELPLLRAALKETLR---LYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGR 389 Query: 397 DDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAG 437 + FP P ++P +LD G+ ++ + +PF G R C G Sbjct: 390 NAALFPRPERYNPQRWLDIRGS-GRNFHHVPFGFGMRQCLG 429 >4OQR-A nrPDB Length = 457 Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 71/264 (26%), Positives = 103/264 (39%), Gaps = 48/264 (18%) Query: 229 THNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLV 288 T ++V + YI E V + S P+D + LI ++ E L Sbjct: 224 TQDEVTTALGKLTRYIAELVATKRLS-----PKDDLLGSLIT--------DTDLTDEELT 270 Query: 289 GTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYT 348 L VAG ETT+ L G LL+HPE A + SP Sbjct: 271 NIALILLVAGHETTANMLGLGTFALLQHPEQIANLD-----------SP----------- 308 Query: 349 DAVVHEIQRYSDLVPTGVPH-AVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIF 407 DA V E+ RY +V G P+ A D + +I KG T+ L +V D K F P+I Sbjct: 309 DA-VEELLRYLSIVHLGTPNRAALEDVELEGQMIRKGDTVAIGLPAVNRDPKVFDEPDIL 367 Query: 408 DPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF---NLKSVDDL 464 LD+ K + F G C G+ LAR+E+ + T + F L + Sbjct: 368 Q----LDRVDARKHA----AFGGGIHQCLGQQLARVEMRIGFTRLFARFPSLRLAVPAEE 419 Query: 465 KNLNTTAVTKGIVSLPPSYQICFI 488 L + G+ +LP ++ I Sbjct: 420 IKLREKSAAYGVWALPVAWDALGI 443 >5VWS-A nrPDB Length = 393 Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 56/226 (24%), Positives = 93/226 (41%), Gaps = 33/226 (14%) Query: 232 KVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTV 291 ++ + VA + + + ++EH S +PRD + L++ E E ++E +V T Sbjct: 173 ELARTVAAAMTEMNDYLREHCRSRR-THPRDDLLTRLVQAEVEG----KRLDLEEVVNTA 227 Query: 292 ADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAV 351 + L +AG TT+ + +L L HPE V+ D S +P A+ Sbjct: 228 SLLLLAGHLTTTVLIGNTMLCLWDHPEAEKAVR---------------ADPSLIPA--AL 270 Query: 352 VHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGH 411 ++ S + G T D IP +MA + S HDD+ FP+P FD Sbjct: 271 EESLRLRSPFLQAG--RVTTRDVTIAGETIPANRFVMAWILSANHDDRRFPDPERFD--- 325 Query: 412 FLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFN 457 +++ + F G C G L R+E + L +L F Sbjct: 326 ------LHRQTTGHIAFGHGVHFCLGAQLGRLEGRIALERLLGRFT 365 >2VZM-A nrPDB Length = 436 Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 48/189 (25%), Positives = 71/189 (37%), Gaps = 27/189 (14%) Query: 267 FLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEE 326 L + + D S E L+G L VAG ETT + G+ LL HP+ A + Sbjct: 233 LLSALVRTSDEDGSRLTSEELLGMAHILLVAGHETTVNLIANGMYALLSHPDQLAAL--- 289 Query: 327 IDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTT 386 R+ M D V E+ RY V + +IP G T Sbjct: 290 ---------------RADMTLLDGAVEEMLRYEGPVESATYRFPVEPVDLDGTVIPAGDT 334 Query: 387 IMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELF 446 ++ +L + FP+P+ FD D G+ F G C G LAR+E Sbjct: 335 VLVVLADAHRTPERFPDPHRFDIRR--DTAGHLA-------FGHGIHFCIGAPLARLEAR 385 Query: 447 LFLTTILQN 455 + + +L+ Sbjct: 386 IAVRALLER 394 >3A1L-A nrPDB Length = 425 Score = 59.7 bits (143), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 47/180 (26%), Positives = 75/180 (41%), Gaps = 28/180 (15%) Query: 277 NQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRS 336 + S +++ +VGT L AG ETT+ L +L L H +V ++ Sbjct: 234 DTGSPLSVDGIVGTCVHLLTAGHETTTNFLAKAVLTLRAHRDVLDEL------------- 280 Query: 337 PCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLH 396 R+ T A V E+ RY V V D + ++ IP+G+ ++ALL S Sbjct: 281 -----RTTPESTPAAVEELMRYDPPV-QAVTRWAYEDIRLGDHDIPRGSRVVALLGSANR 334 Query: 397 DDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF 456 D FP+P++ D + ++ + F G C G LAR E + L +L Sbjct: 335 DPARFPDPDVLD---------VHRAAERQVGFGLGIHYCLGATLARAEAEIGLRALLDGI 385 >4OQS-A nrPDB Length = 433 Score = 59.3 bits (142), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 70/259 (27%), Positives = 102/259 (39%), Gaps = 48/259 (18%) Query: 229 THNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLV 288 T ++V + YI E V + S P+D + LI ++ E L Sbjct: 185 TQDEVTTALGKLTRYIAELVATKRLS-----PKDDLLGSLIT--------DTDLTDEELT 231 Query: 289 GTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYT 348 L VAG ETT+ L G LL+HPE A + SP Sbjct: 232 NIALLLLVAGHETTANMLGLGTFALLQHPEQIAALD-----------SP----------- 269 Query: 349 DAVVHEIQRYSDLVPTGVPH-AVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIF 407 DA V E+ RY +V G P+ A D + +I KG T+ L +V D K F P+I Sbjct: 270 DA-VEELLRYLSIVHLGTPNRAALEDVELEGQMIRKGDTVAIGLPAVNRDPKVFDEPDIL 328 Query: 408 DPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF---NLKSVDDL 464 LD+ K + F G C G+ LAR+E+ + T + F L + Sbjct: 329 Q----LDRVDARKHA----AFGGGIHQCLGQQLARVEMRIGFTRLFARFPSLRLAVPAEE 380 Query: 465 KNLNTTAVTKGIVSLPPSY 483 L + G+ +LP ++ Sbjct: 381 IKLREKSAAYGVWALPVAW 399 >5FSA-A nrPDB Length = 490 Score = 59.3 bits (142), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 67/302 (22%), Positives = 123/302 (40%), Gaps = 43/302 (14%) Query: 191 DQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIRE-KVK 249 D++F L ++ F +N V N PL P + ++ +Y++E K++ Sbjct: 172 DRSFAQLYSDLDKGFTPINF----VFPNLPL-----PHYWRRDAAQKKISATYMKEIKLR 222 Query: 250 EHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYG 309 + +D N RD ID LI + + ++ I NL+ + + G T+++T + Sbjct: 223 RERGDIDPN--RDLIDSLLIHSTYKDGVKMTDQEIANLL---IGILMGGQHTSASTSAWF 277 Query: 310 LLLLLKHPEVTAKVQEEIDHVI----GRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTG 365 LL L + P + + +E+ ++ G +D +P + + E R + Sbjct: 278 LLHLGEKPHLQDVIYQEVVELLKEKGGDLNDLTYEDLQKLPSVNNTIKETLRMH-MPLHS 336 Query: 366 VPHAVTTDTKF--RNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNG-----N 418 + VT + NY++PKG ++ ++ F NP FDP + + Sbjct: 337 IFRKVTNPLRIPETNYIVPKGHYVLVSPGYAHTSERYFDNPEDFDPTRWDTAAAKANSVS 396 Query: 419 FKKSDY---------------FMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDD 463 F SD ++PF G+ C GE A ++L LTT + N ++D Sbjct: 397 FNSSDEVDYGFGKVSKGVSSPYLPFGGGRHRCIGEQFAYVQLGTILTTFVYNLRW-TIDG 455 Query: 464 LK 465 K Sbjct: 456 YK 457 >2W0A-A nrPDB Length = 455 Score = 58.5 bits (140), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 47/202 (23%), Positives = 90/202 (44%), Gaps = 9/202 (4%) Query: 261 RDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVT 320 RD +D LI ++ E + F+ + + G + AG T+S T + L+ L++H + Sbjct: 223 RDMLDV-LIAVKAETGTPR--FSADEITGMFISMMFAGHHTSSGTASWTLIELMRHRDAY 279 Query: 321 AKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKF--RN 378 A V +E+D + G RS +P + V+ E R L P + +F + Sbjct: 280 AAVIDELDELYGDGRSVSFHALRQIPQLENVLKETLR---LHPPLIILMRVAKGEFEVQG 336 Query: 379 YLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLD-KNGNFKKSDYFMPFSAGKRICAG 437 + I +G + A ++FP+P+ F P + + + ++PF AG+ C G Sbjct: 337 HRIHEGDLVAASPAISNRIPEDFPDPHDFVPARYEQPRQEDLLNRWTWIPFGAGRHRCVG 396 Query: 438 EGLARMELFLFLTTILQNFNLK 459 A M++ + +L+ + + Sbjct: 397 AAFAIMQIKAIFSVLLREYEFE 418 >5FOI-A nrPDB Length = 408 Score = 58.5 bits (140), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 47/177 (26%), Positives = 76/177 (42%), Gaps = 28/177 (15%) Query: 279 KSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPC 338 K E + LV L AG ET++ + +L LL+HPE A+++E+ P Sbjct: 229 KGEITHQELVNNAVLLLAAGHETSANQVTLSVLTLLRHPETAAELREQ----------PE 278 Query: 339 MQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDD 398 + MP V E+ RY + G+ A T D ++ I G ++ LL+S HD Sbjct: 279 L-----MPNA---VDELLRYHSIA-DGLRRAATADIVLGDHTIRAGDGLIILLSSANHDG 329 Query: 399 KEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQN 455 F FD + + + + F G C G+ LAR+E+ + L + + Sbjct: 330 NTFGAEATFD---------IHRPARHHVAFGYGPHQCLGQNLARLEMEVTLGKLFRR 377 >1Q5D-A nrPDB Length = 419 Score = 58.2 bits (139), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 45/192 (23%), Positives = 80/192 (41%), Gaps = 29/192 (15%) Query: 265 DCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQ 324 D + ++ E D S + + LV V + AGT+TT + + +L LL+ PE V+ Sbjct: 224 DVLTMLLQAEADG--SRLSTKELVALVGAIIAAGTDTTIYLIAFAVLNLLRSPEALELVK 281 Query: 325 EEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKG 384 E P + + + E+ R+ +++ G D ++ I KG Sbjct: 282 AE----------PGLMRNA--------LDEVLRFDNILRIGTVRFARQDLEYCGASIKKG 323 Query: 385 TTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARME 444 + L+ S L D F P++FD + + + + G +C G LAR+E Sbjct: 324 EMVFLLIPSALRDGTVFSRPDVFD---------VRRDTSASLAYGRGPHVCPGVSLARLE 374 Query: 445 LFLFLTTILQNF 456 + + TI + F Sbjct: 375 AEIAVGTIFRRF 386 >3TYW-A nrPDB Length = 417 Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 49/175 (28%), Positives = 79/175 (45%), Gaps = 35/175 (20%) Query: 285 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSH 344 E L+ T+ AG ETT++ + LLLL PE+ A+++++ D Sbjct: 237 EQLLSTLGITINAGRETTTSMIALSTLLLLDRPELPAELRKDPD---------------L 281 Query: 345 MPYTDAVVHEIQR---YSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEF 401 MP A V E+ R +D +P V D + +P ++ALL HD ++F Sbjct: 282 MP---AAVDELLRVLSVADSIPLRV---AAEDIELSGRTVPADDGVIALLAGANHDPEQF 335 Query: 402 PNPNIFDPGHFLDKNGNFKKSD-YFMPFSAGKRICAGEGLARMELFLFLTTILQN 455 +P D F ++D + + F G C G+ LAR+EL + L T+L+ Sbjct: 336 DDPERVD----------FHRTDNHHVAFGYGVHQCVGQHLARLELEVALETLLRR 380 >3EJB-B nrPDB Length = 404 Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 50/180 (27%), Positives = 75/180 (41%), Gaps = 28/180 (15%) Query: 275 KDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRH 334 K +K + E T L +AG ETT + +L LL+HPE K++E D +IG Sbjct: 212 KGREKDKLTEEEAASTCILLAIAGHETTVNLISNSVLCLLQHPEQLLKLRENPD-LIGTA 270 Query: 335 RSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSV 394 C++ S T V E D+ GV I +G + LL + Sbjct: 271 VEECLRYESPTQMTARVASE-----DIDICGV-------------TIRQGEQVYLLLGAA 312 Query: 395 LHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQ 454 D F NP++FD + + + F G +C G LAR+E + + T+LQ Sbjct: 313 NRDPSIFTNPDVFDIT---------RSPNPHLSFGHGHHVCLGSSLARLEAQIAINTLLQ 363 >5YSW-A nrPDB Length = 441 Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 62/256 (24%), Positives = 107/256 (41%), Gaps = 42/256 (16%) Query: 232 KVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEF-NIENLVGT 290 + +KN R++++ V + +A N D I + + E NI NL Sbjct: 221 EAVKNADALRAFMQALVTDKRA----NPAGDIISGLIHHAGADPALTDDELINIANL--- 273 Query: 291 VADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDA 350 L +AG +TT++ L G+ +LL+ P A ++++ + DA Sbjct: 274 ---LLIAGYDTTASMLGLGIFVLLQRPAQLATLRDDPSRI-----------------ADA 313 Query: 351 VVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPG 410 V E+ RY +V G+ D +F IP G+T++ + + D + +P+P+ Sbjct: 314 V-EELLRYLSVVNPGIFRFAKEDLEFAGEHIPAGSTVVVSVVATNRDARHWPDPD----- 367 Query: 411 HFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMEL---FLFLTTILQNFNLKSVDDLKNL 467 LD + + F G C G+ LARME+ + L L N L + L Sbjct: 368 --LDLT---RPRGPHLAFGHGVHQCLGQQLARMEMQAGYAELLRRLPNVRLAVPPEEVPL 422 Query: 468 NTTAVTKGIVSLPPSY 483 +T G+ SLP ++ Sbjct: 423 RNDMLTYGVHSLPIAW 438 >2ZBZ-A nrPDB Length = 412 Score = 55.5 bits (132), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 42/174 (24%), Positives = 71/174 (40%), Gaps = 27/174 (15%) Query: 280 SEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCM 339 E + E L+ T L +AG ETT++ ++ LL HPE A ++ Sbjct: 227 GEIDREELISTAMLLLIAGHETTASMTSLSVITLLDHPEQYAALR--------------- 271 Query: 340 QDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDK 399 DRS +P V E+ RY + T D + LI G ++ + + D Sbjct: 272 ADRSLVP---GAVEELLRYLAIADIAGGRVATADIEVEGQLIRAGEGVIVVNSIANRDGT 328 Query: 400 EFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTIL 453 + +P+ D + + + + F G C G+ LAR+EL + L ++ Sbjct: 329 VYEDPDALD---------IHRSARHHLAFGFGVHQCLGQNLARLELEVILNALM 373 >6M7X-A nrPDB Length = 484 Score = 55.5 bits (132), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 40/160 (25%), Positives = 69/160 (43%), Gaps = 6/160 (3%) Query: 280 SEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCM 339 +E + + + +L +TT L L L ++P V +++E Sbjct: 274 AELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQ 333 Query: 340 QDRSHMPYTDAVVHEIQRYSDLVPTGV--PHAVTTDTKFRNYLIPKGTTIMALLTSVLHD 397 + + +P A + E R L P G+ ++D +NY IP GT + L S+ + Sbjct: 334 KATTELPLLRAALKETLR---LYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRN 390 Query: 398 DKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAG 437 FP P ++P +LD G+ ++ Y +PF G R C G Sbjct: 391 PALFPRPERYNPQRWLDIRGS-GRNFYHVPFGFGMRQCLG 429 >6M7L-A nrPDB Length = 404 Score = 55.1 bits (131), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 54/209 (25%), Positives = 79/209 (37%), Gaps = 38/209 (18%) Query: 277 NQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRS 336 + ++ + E L G A + + E T + L G LLLL+HPE A ++E + Sbjct: 224 DHGADISDEELAGLCAVVMNSSVEQTESCLAAGTLLLLEHPEQFALLRERPE-------- 275 Query: 337 PCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLH 396 + V EI RY + P T D + +I KG + L + Sbjct: 276 ----------LGEQAVEEIVRYLSVFEGLDPRTATEDVEIGGQVIKKGEAVFCSLLAA-- 323 Query: 397 DDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF 456 N DP LD +K + F G C G LARMEL + TT++ F Sbjct: 324 --------NRADPA--LDGFDITRKESRHVAFGHGIHHCLGAPLARMELRIAFTTLVSRF 373 Query: 457 NLKSVDDLKNLNTTAVTKGIVSLPPSYQI 485 +L T + I PPS + Sbjct: 374 --------PSLRTAVPAEEIRFRPPSSNV 394 >6GK6-A nrPDB Length = 411 Score = 54.7 bits (130), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 50/195 (25%), Positives = 74/195 (37%), Gaps = 32/195 (16%) Query: 262 DFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTA 321 D I L+ EQE +E L V L VAG ETT + G+LLLL HP Sbjct: 213 DLISGLLLAEEQEHKLSPAE-----LSSMVFLLLVAGHETTVHLIASGMLLLLSHPAERR 267 Query: 322 KVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLI 381 ++ E+ P + + V E R D + + Sbjct: 268 RLDED----------PGL--------VGSAVEEALRCEGPAELSTIRWSLEDIELFGARV 309 Query: 382 PKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLA 441 P G + A L + D + FP+P+ FD G + + + F G C G LA Sbjct: 310 PAGEGVAAGLLAANRDPQHFPDPDRFDIG---------RSPNRHIGFGGGIHFCLGAMLA 360 Query: 442 RMELFLFLTTILQNF 456 R+E + +T+L+ Sbjct: 361 RIEAAIAFSTLLRRL 375 >5CJE-A nrPDB Length = 393 Score = 54.7 bits (130), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 51/214 (23%), Positives = 83/214 (38%), Gaps = 34/214 (15%) Query: 242 SYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTET 301 +Y+ E + + +++ P D + LI+ E D++ S E L L VAG ET Sbjct: 185 AYLDELIDDKRST----APADDLLGDLIRTRAEDDDRLSG---EELRAMAFILLVAGHET 237 Query: 302 TSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDL 361 T + G+ LL HP+ A + R+ M D V E+ R+ Sbjct: 238 TVNLITNGVHTLLTHPDQLAAL------------------RADMTLLDGAVEEVLRFEGP 279 Query: 362 VPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKK 421 V T + I +G +M L + D P+P++FD + Sbjct: 280 VETATYRYAAESMEIGGTAIAEGDPVMIGLDAAGRDPARHPDPHVFD---------IHRA 330 Query: 422 SDYFMPFSAGKRICAGEGLARMELFLFLTTILQN 455 + F G C G LAR+E + L ++L+ Sbjct: 331 PQGHLAFGHGIHYCLGAPLARLEARVALRSLLER 364 >6GMF-A nrPDB Length = 397 Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 44/164 (26%), Positives = 66/164 (40%), Gaps = 28/164 (17%) Query: 294 LFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVH 353 L +AG ETT++ + L+ L HPE A Q ++ V AVV Sbjct: 230 LLIAGNETTTSLIGNALVALTDHPEQLAAAQADLSLV------------------PAVVE 271 Query: 354 EIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFL 413 E+ RY + TD + + IP + ++ LL S D+ FP+P+ FD Sbjct: 272 EVLRYESPAQC-IFRQTMTDVEIGDERIPARSVVLPLLASANRDESRFPDPDRFDIHR-- 328 Query: 414 DKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFN 457 D G+ + F C G LAR+E + L +L Sbjct: 329 DTKGH-------LAFGLDIHFCIGAPLARLEAKVMLEVLLARLG 365 >2Y5N-A nrPDB Length = 417 Score = 53.9 bits (128), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 72/322 (22%), Positives = 120/322 (37%), Gaps = 68/322 (21%) Query: 140 SIEDRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNVICSVVFQKRFDYKDQNFLTLM 198 S+ R +E AH LV+++ T P D + P VIC ++ D+ Sbjct: 129 SLRPRAREIAHELVDQMAAT-GQPADLVAMFARQLPVRVICELLGVPSADH--------- 178 Query: 199 KRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASL-DV 257 D F L +T ++E ++ A + D+ Sbjct: 179 -------------------------DRFTRWSGAFLSTAEVTAEEMQEAAEQAYAYMGDL 213 Query: 258 NNPR--DFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLK 315 + R + D + + Q +D Q S + + L+ L VAG E+T+T + + LL+ Sbjct: 214 IDRRRKEPTDDLVSALVQARDQQDS-LSEQELLDLAIGLLVAGYESTTTQIADFVYLLMT 272 Query: 316 HPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDL-VPTGVPHAVTTDT 374 PE+ + + DR + + V E+ R+ L V T P D Sbjct: 273 RPELRRQ----------------LLDRPEL--IPSAVEELTRWVPLGVGTAFPRYAVEDV 314 Query: 375 KFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRI 434 R I G ++A + D +FP+ + D +D+ N + F G Sbjct: 315 TLRGVTIRAGEPVLASTGAANRDQAQFPDADRID----VDRTPN-----QHLGFGHGVHH 365 Query: 435 CAGEGLARMELFLFLTTILQNF 456 C G LAR+EL + L +LQ Sbjct: 366 CLGAPLARVELQVALEVLLQRL 387 >4RM4-A nrPDB Length = 396 Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 50/199 (25%), Positives = 84/199 (42%), Gaps = 32/199 (16%) Query: 258 NNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHP 317 N P I L++ E+ + + + E L+ L VAG ETT+ + + +L+ P Sbjct: 204 NKPEQDIISILVEAEETGE----KLSGEELIPFCTLLLVAGNETTTNLISNAMYSILETP 259 Query: 318 EVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFR 377 V EE+ RSH V E R+ P + DT+ Sbjct: 260 ----GVYEEL--------------RSHPELMPQAVEEALRFRAPAPV-LRRIAKRDTEIG 300 Query: 378 NYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAG 437 +LI +G ++A + S D+ +F P++FD + ++ N + F G C G Sbjct: 301 GHLIKEGDMVLAFVASANRDEAKFDRPHMFD----IRRHPN-----PHIAFGHGIHFCLG 351 Query: 438 EGLARMELFLFLTTILQNF 456 LAR+E + LT+++ F Sbjct: 352 APLARLEANIALTSLISAF 370 >2X2N-A nrPDB Length = 475 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 45/188 (23%), Positives = 78/188 (41%), Gaps = 19/188 (10%) Query: 282 FNIENLVGTVADLFVAGTETTSTTLRYGLLLLL-----KHPEVTAKVQEEIDHVIGRHRS 336 ++ + G + AG T+S T + +L L+ KH E K EE + + Sbjct: 262 MSLHEVCGMIVAAMFAGQHTSSITTTWSMLHLMHPANVKHLEALRKEIEEFPAQLNYNNV 321 Query: 337 PCMQDRSHMPYTDAVVHE-IQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVL 395 MP+ + E I+R L+ + V D K +Y++PKG I Sbjct: 322 -----MDEMPFAERCARESIRRDPPLL--MLMRKVMADVKVGSYVVPKGDIIACSPLLSH 374 Query: 396 HDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQN 455 HD++ FP P +DP + K F+ F AG C G+ +++ L T ++ Sbjct: 375 HDEEAFPEPRRWDP------ERDEKVEGAFIGFGAGVHKCIGQKFGLLQVKTILATAFRS 428 Query: 456 FNLKSVDD 463 ++ + + D Sbjct: 429 YDFQLLRD 436 >3ABB-A nrPDB Length = 408 Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 55/212 (25%), Positives = 86/212 (40%), Gaps = 39/212 (18%) Query: 242 SYIREKVKEHQASLDVNNPRD-FIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTE 300 +Y+ V QA P D +D + + +E D E + LV L VAG E Sbjct: 197 TYLHGLVGRKQA-----EPEDGLLDELIARQLEEGDLDHDEVVMIALV-----LLVAGHE 246 Query: 301 TTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSD 360 TT + G L L++HP E+ID ++ R P VV E+ R++ Sbjct: 247 TTVNAIALGALTLIQHP-------EQIDVLL---RDPGA--------VSGVVEELLRFTS 288 Query: 361 LVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFK 420 V + D + I G ++ +T + D K + NP+IFD + Sbjct: 289 -VSDHIVRMAKEDIEVGGATIKAGDAVLVSITLMNRDAKAYENPDIFD---------ARR 338 Query: 421 KSDYFMPFSAGKRICAGEGLARMELFLFLTTI 452 + + + F G C G+ LAR EL + L + Sbjct: 339 NARHHVGFGHGIHQCLGQNLARAELEIALGGL 370 >6B11-A nrPDB Length = 440 Score = 52.8 bits (125), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 31/193 (16%) Query: 294 LFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVH 353 L AG ETT++ + +L+LL+HP TA + ++ P + +P V Sbjct: 276 LLAAGHETTASMVTMSVLVLLQHP--TAWRELTVN--------PGL-----LP---GAVD 317 Query: 354 EIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFL 413 E+ RY + G+ + T D + + I G ++ LL + D+ F P FD Sbjct: 318 ELLRYLSIA-DGLRRSATADIEIDGHTIRAGDGLVFLLAAANRDEAVFSEPEAFD----- 371 Query: 414 DKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF-NLKSVDDLKN--LNTT 470 + + + F G C G+ LARMEL + L +L+ L+ D+ L + Sbjct: 372 ----IHRSARRHVAFGYGPHQCLGQNLARMELEVALGAVLERLPALRPTTDVAGLRLKSD 427 Query: 471 AVTKGIVSLPPSY 483 + G+ LP ++ Sbjct: 428 SAVFGVYELPVAW 440 >3SN5-A nrPDB Length = 491 Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 115/514 (22%), Positives = 197/514 (38%), Gaps = 84/514 (16%) Query: 21 RQSCRRRKLPPGPTP---LPIIGNMLQIDVKDICKSFTNFSKVYGPVFT-------VYFG 70 + S RRR+ P +P +G LQ + N K +G VFT V+F Sbjct: 4 KTSSRRRQTGEPPLENGLIPYLGCALQFGANPLEFLRANQRK-HGHVFTCKLMGKYVHFI 62 Query: 71 MNPI----VVFHG--YEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIR 124 NP+ V+ HG ++ K + + F R P+ T+ + N K ++ Sbjct: 63 TNPLSYHKVLCHGKYFDWKKFHFALSAKAFGHRSIDPMDGNTTENI-----NDTFIKTLQ 117 Query: 125 RFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQ 184 +L +L ++E L++ P + S ++ Sbjct: 118 GHALNSL-----------------TESMMENLQRIMRPPVSSNSKTAAWVTEGMYSFCYR 160 Query: 185 KRFDYKDQNFLT-----LMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVAL 239 F+ +LT L +R + ILN+ +NF FP + ++ Sbjct: 161 VMFE---AGYLTIFGRDLTRRDTQKAHILNN-----LDNFKQFDKVFPALVAGLPIHMFR 212 Query: 240 TRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFN-IENLVGTVADLFVAG 298 T REK+ E ++ + LI + ++ S F+ +E + L+ + Sbjct: 213 TAHNAREKLAESLRHENLQKRESISE--LISLRMFLNDTLSTFDDLEKAKTHLVVLWASQ 270 Query: 299 TETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVI---GRHRS-----PCMQ--DRSHMPYT 348 T T + L ++++PE EE+ + G+ S C+ + + +P Sbjct: 271 ANTIPATF-WSLFQMIRNPEAMKAATEEVKRTLENAGQKVSLEGNPICLSQAELNDLPVL 329 Query: 349 DAVVHEIQRYSD--LVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKE-FPNPN 405 D+++ E R S L T + +Y I K I+AL ++H D E +P+P Sbjct: 330 DSIIKESLRLSSASLNIRTAKEDFTLHLEDGSYNIRKDD-IIALYPQLMHLDPEIYPDPL 388 Query: 406 IFDPGHFLDKNGNFKKS---------DYFMPFSAGKRICAGEGLARMELFLFLTTILQNF 456 F +LD+NG K + Y+MPF +G IC G A E+ FL +L F Sbjct: 389 TFKYDRYLDENGKTKTTFYCNGLKLKYYYMPFGSGATICPGRLFAIHEIKQFLILMLSYF 448 Query: 457 NLKSVDDLKN---LNTTAVTKGIVSLPPSYQICF 487 L+ ++ L+ + GI LPP I F Sbjct: 449 ELELIEGQAKCPPLDQSRAGLGI--LPPLNDIEF 480 >6F0B-A nrPDB Length = 395 Score = 52.0 bits (123), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 53/230 (23%), Positives = 92/230 (40%), Gaps = 30/230 (13%) Query: 257 VNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKH 316 V +P + + LI+ Q+ + +G + L V G +TT++T+ L+ Sbjct: 193 VQDPSELPEDSLIRRLVTGPYQEKQLTFHETIGVILMLIVGGYDTTASTISLSLVSYALQ 252 Query: 317 PEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKF 376 PE + V E + R P + V E+ RY + G+ T D + Sbjct: 253 PEKFSVVHEHPE------RIPLL------------VEELLRYHTVSQLGLGRIATEDVEV 294 Query: 377 RNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICA 436 + G ++A L D+ FPNP+ D D + S + F G C Sbjct: 295 GGVTVRAGQMVVAALPLANRDESVFPNPDELD----FD-----RPSVPHVGFGYGPHQCV 345 Query: 437 GEGLARMELFLFLTTILQNF-NLKSVDDLKNL--NTTAVTKGIVSLPPSY 483 G+ LAR+EL + +++ ++ L++L T GI LP ++ Sbjct: 346 GQALARVELQEAIPAVIRRLPGMRLACALEDLPFRHDMATYGIHELPMTW 395 >6CR2-A nrPDB Length = 477 Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 49/214 (22%), Positives = 93/214 (43%), Gaps = 31/214 (14%) Query: 285 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDR-S 343 E + + L +AG ++S+T + +L L P++ ++ +E V+G P D Sbjct: 249 EEIAHMMIALLMAGQHSSSSTASWIVLRLATRPDIMEELYQEQIRVLGSDLPPLTYDNLQ 308 Query: 344 HMPYTDAVVHEIQR-----YSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDD 398 + V+ E R +S + P AV + Y+IP +++ + Sbjct: 309 KLDLHAKVIKETLRLHAPIHSIIRAVKNPMAVDGTS----YVIPTSHNVLSSPGVTARSE 364 Query: 399 KEFPNPNIFDPGHFLDKN-----GNFKKSDY------------FMPFSAGKRICAGEGLA 441 + FPNP ++P H D+N + +K DY ++PF AG+ C GE A Sbjct: 365 EHFPNPLEWNP-HRWDENIAASAEDDEKVDYGYGLVSKGTNSPYLPFGAGRHRCIGEQFA 423 Query: 442 RMELFLFLTTILQNF---NLKSVDDLKNLNTTAV 472 ++L +++ F NL VD + + + +++ Sbjct: 424 YLQLGTITAVLVRLFRFRNLPGVDGIPDTDYSSL 457 >4UBS-A nrPDB Length = 393 Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 84/355 (23%), Positives = 136/355 (38%), Gaps = 81/355 (22%) Query: 140 SIEDRVQEEAHCLVEELRKTKASPCD--PTFILGCAPCNVICSVVFQKRFDYKDQNFLTL 197 ++ R+QE L++ + + + P + F L P VIC+++ Y D +F Sbjct: 109 ALRPRIQETVDGLLDAM-EAQGPPAELVSAFALPL-PSMVICALLG---VPYADHDFFES 163 Query: 198 MKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDV 257 R R+L P I + +D + + I K KE Sbjct: 164 QSR-----RLLRGPGIAEVQDARAQLDDY-------------LYALIDRKRKEPG----- 200 Query: 258 NNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHP 317 D L + QE+ N+ + E LV L +AG ETT+ + G LL+HP Sbjct: 201 -------DGLLDDLIQEQLNRGTVDRAE-LVSLATLLLIAGHETTANMISLGTFTLLRHP 252 Query: 318 EVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFR 377 E A+++ E P + MP A V E+ R+ + G+ T D + Sbjct: 253 EQLAELRAE----------PGL-----MP---AAVEELLRFLSIA-DGLLRVATEDIEV- 292 Query: 378 NYLIPKGTTIMA-----LLTSVLHDDKE-FPNPNIFDPGHFLDKNGNFKKSDYFMPFSAG 431 GTTI A TSV++ D F P+ D + + + + F G Sbjct: 293 -----AGTTIRADEGVVFATSVINRDAAGFAEPDALD---------WHRSARHHVAFGFG 338 Query: 432 KRICAGEGLARMELFLFLTTI---LQNFNLKSVDDLKNLNTTAVTKGIVSLPPSY 483 C G+ LAR E+ + L T+ L L + D +G++ LP ++ Sbjct: 339 IHQCLGQNLARAEMEIALGTLFERLPGLRLAAPADEIPFKPGDTIQGMLELPVTW 393 >4GGV-A nrPDB Length = 418 Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 55/210 (26%), Positives = 85/210 (40%), Gaps = 38/210 (18%) Query: 259 NPRDFIDCFLIKME--QEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKH 316 PR+ + L++ E E+ N+ N+ L V G TT+ TL +L L Sbjct: 223 TPREDLLTHLVQAEVDGERLTDNEIVNVANI------LLVTGHITTTMTLGNTVLCLDAD 276 Query: 317 PEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTG-VPHAVTTDTK 375 PEV AKV+ DRS +P + E R L P+ + + + + Sbjct: 277 PEVAAKVR---------------ADRSLVP---GAIEEALRV--LSPSAALARGTSREVE 316 Query: 376 FRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRIC 435 +IPK +M L + D ++F +P ++DP D N +F F G C Sbjct: 317 VAGTVIPKDQIVMLWLGAGNRDPRQFTDPEVYDPTR--DPNPHFG-------FGRGIHFC 367 Query: 436 AGEGLARMELFLFLTTILQNFNLKSVDDLK 465 G LAR+E + L + F + D K Sbjct: 368 LGAPLARLEGRVALNALFDRFPVLRTDPAK 397 >3L4D-A nrPDB Length = 453 Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 47/194 (24%), Positives = 83/194 (42%), Gaps = 14/194 (7%) Query: 286 NLVGTVADLFVAGTETTSTTLRYGLLLLL--KHPEVTAKVQEEIDHVIGRHRSPCMQDRS 343 + G + AG T++ T + LL L+ ++ AK+ +EID + + + Sbjct: 252 EVCGMIVAAMFAGQHTSTITTTWSLLHLMDPRNKRHLAKLHQEIDEFPAQLNYDNVMEE- 310 Query: 344 HMPYTDAVVHE-IQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFP 402 MP+ + E I+R LV + V + Y++P+G I D++ FP Sbjct: 311 -MPFAEQCARESIRRDPPLV--MLMRKVLKPVQVGKYVVPEGDIIACSPLLSHQDEEAFP 367 Query: 403 NPNIFDPGHFLDKNGNFKKSD-YFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSV 461 NP ++P N K D F F AG C GE +++ L T+L++++ + + Sbjct: 368 NPREWNP------ERNMKLVDGAFCGFGAGVHKCIGEKFGLLQVKTVLATVLRDYDFELL 421 Query: 462 DDLKNLNTTAVTKG 475 L N + G Sbjct: 422 GPLPEPNYHTMVVG 435 >3TKT-A nrPDB Length = 450 Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 53/194 (27%), Positives = 84/194 (43%), Gaps = 36/194 (18%) Query: 297 AGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQ 356 AG +TTS + L L + P++ A+V+ DR+ +P +V E Sbjct: 289 AGHDTTSASSAGAALALARDPDLFARVK---------------ADRNLLP---GIVEEAI 330 Query: 357 RYSDLVPTGVPH---AVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFL 413 R++ T V H TDT+ I G +M + HD +FP P FDP Sbjct: 331 RWT----TPVQHFMRTAATDTELCGQKIAAGDWLMLNYVAANHDPAQFPEPRKFDP---- 382 Query: 414 DKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFN-LKSVDDLKNLNTTAV 472 + ++ + F AG C G LAR+E+ + L +L + L+ + K +N+T V Sbjct: 383 -----TRPANRHLAFGAGSHQCLGLHLARLEMRVLLDVLLDRVDSLELAGEPKRVNSTFV 437 Query: 473 TKGIVSLPPSYQIC 486 G SLP ++ Sbjct: 438 -GGFKSLPMRWKAA 450 >4TRI-A nrPDB Length = 407 Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 64/267 (23%), Positives = 106/267 (39%), Gaps = 55/267 (20%) Query: 231 NKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQK---SEFNIENL 287 K++ A + ++ + + +A P D D F + + E + Q+ E E L Sbjct: 176 QKLMDTFAAYTEFTKDVITKRRAE-----PTD--DLFSVLVNSEVEGQRMSDDEIVFETL 228 Query: 288 VGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPY 347 + + + G ETT TL G LL+H + + ++D + G Sbjct: 229 L-----ILIGGDETTRHTLSGGTEQLLRHRDQWDALVADVDLLPG--------------- 268 Query: 348 TDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIF 407 + E+ R++ V + +T DT F + G IM + S D+ F +P+ F Sbjct: 269 ---AIEEMLRWTSPV-KNMCRTLTADTVFHGTELRAGEKIMLMFESANFDESVFGDPDNF 324 Query: 408 DPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF-NLKSVDD--- 463 +D+N N + F G C G LAR+EL L +L+ +L+ DD Sbjct: 325 R----IDRNPN-----SHVAFGFGTHFCLGNQLARLELRLMTERVLRRLPDLRLADDAPV 375 Query: 464 -LKNLNTTAVTKGIVSLPPSYQICFIP 489 L+ N VS P S + F P Sbjct: 376 PLRPAN-------FVSGPESMPVVFTP 395 >4WPZ-A nrPDB Length = 397 Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 55/232 (23%), Positives = 99/232 (42%), Gaps = 37/232 (15%) Query: 258 NNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHP 317 NP D + LI + + D+ +E I + + AG ETT+ + L+ LL +P Sbjct: 197 ENPADDLISELIAI-SDGDSTLTEREI---IALSIGILSAGHETTANQISMFLVTLLHNP 252 Query: 318 EVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTG--VPHAVTTDTK 375 E K+++ +R +P V E+ R+ L TG +P T + + Sbjct: 253 EELDKLRD---------------NREAIPKA---VDELLRFVPLTTTGGIIPRLTTAEVE 294 Query: 376 FR-NYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRI 434 ++P G ++ + + D P +F+ G L+ ++++ + F AG Sbjct: 295 LSGGQVLPAGAVVLPAVATANRD------PEVFEDGERLNVT---RENNPHLAFGAGIHH 345 Query: 435 CAGEGLARMELFLFLTTILQNF---NLKSVDDLKNLNTTAVTKGIVSLPPSY 483 C G LAR+EL L IL L + L + ++ +G+ SLP ++ Sbjct: 346 CLGAQLARIELQEALGAILDRMPQVRLAVPESELRLKSASIIRGLESLPITW 397 >3R9C-A nrPDB Length = 418 Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 52/226 (23%), Positives = 86/226 (38%), Gaps = 37/226 (16%) Query: 231 NKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGT 290 ++ +K R Y+R + E + P + + L+ +E+ D + + ++ T Sbjct: 199 DEQMKAGMWLRDYLRALIDERR-----RTPGEDLMSGLVAVEESGD----QLTEDEIIAT 249 Query: 291 VADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDA 350 L +AG ETT + L +L+ P A + + G S A Sbjct: 250 CNLLLIAGHETTVNLIANAALAMLRTPGQWAALAAD-----GSRAS-------------A 291 Query: 351 VVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPG 410 V+ E RY V V D + +PKG T++ LL + D P+ FDP Sbjct: 292 VIEETMRYDPPVQL-VSRYAGDDLTIGTHTVPKGDTMLLLLAAAHRDPTIVGAPDRFDPD 350 Query: 411 HFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF 456 ++ F K +F C G LAR+E + L + F Sbjct: 351 RAQIRHLGFGKGAHF---------CLGAPLARLEATVALPALAARF 387 >2Z36-A nrPDB Length = 413 Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 48/207 (23%), Positives = 75/207 (36%), Gaps = 38/207 (18%) Query: 261 RDFIDCFLIKMEQE-----------KDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYG 309 R +ID + + E E + Q+ + LV L AG ETT+ + G Sbjct: 198 RAYIDDLITRKESEPGDDLFSRQIARQRQEGTLDHAGLVSLAFLLLTAGHETTANMISLG 257 Query: 310 LLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHA 369 ++ LL HPE V+ GR T V E+ RY + Sbjct: 258 VVGLLSHPEQLTVVKAN----PGR--------------TPMAVEELLRYFTIADGVTSRL 299 Query: 370 VTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFS 429 T D + I G ++ + S D F +P + D + + + + F Sbjct: 300 ATEDVEIGGVSIKAGEGVIVSMLSANWDPAVFKDPAVLD---------VERGARHHLAFG 350 Query: 430 AGKRICAGEGLARMELFLFLTTILQNF 456 G C G+ LARMEL + T+ + Sbjct: 351 FGPHQCLGQNLARMELQIVFDTLFRRI 377 >5EX6-C nrPDB Length = 434 Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 47/206 (22%), Positives = 81/206 (39%), Gaps = 33/206 (16%) Query: 285 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSH 344 E L G + +AG + S + G+L LL++PE A + R Sbjct: 260 EELRGVCVQMMLAGDDNISGMIGLGVLALLRNPEQIAAL------------------RGD 301 Query: 345 MPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNP 404 +P + V E+ RY + P D+ + +I G T++ L + D P+ Sbjct: 302 VPAAERAVDELIRYLTVPYAPTPRTAIEDSTVGDQVIKAGETVLCSLPTANRDPALLPDA 361 Query: 405 NIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDL 464 + D +++ + F G C G LAR+EL + T + + F DL Sbjct: 362 DRLD---------VTREAVPHVAFGHGVHHCLGAALARLELRIAYTALWRRFP-----DL 407 Query: 465 KNLNTTAVTKGIVSLPPSYQICFIPV 490 + + T+ +S P+Y I + V Sbjct: 408 RLADPDGATEFRLST-PAYGISRLMV 432 >4YZR-A nrPDB Length = 405 Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 63/267 (23%), Positives = 103/267 (38%), Gaps = 45/267 (16%) Query: 222 LIDCFPGTHNKVLKNVALT--RSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQK 279 ++D G N+ L N AL + YI + + + + P+D + L+ E+ Sbjct: 175 MVDTSEG--NRELTNQALREFKDYIAKLIHDRRIK-----PKDDLISKLVHAEE----NG 223 Query: 280 SEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCM 339 S+ + + L + L VAG ETT L G L LL+H + K++++ + + Sbjct: 224 SKLSEKELYSMLFLLVVAGLETTVNLLGSGTLALLQHKKECEKLKQQPEMIA-------- 275 Query: 340 QDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDK 399 V E+ RY+ V D ++ + I +G I + S D Sbjct: 276 ----------TAVEELLRYTSPVVMMANRWAIEDFTYKGHSIKRGDMIFIGIGSANRDPN 325 Query: 400 EFPNPNIFDPGHFLDKNGNFKKS-DYFMPFSAGKRICAGEGLARMELFLFLTTILQNF-- 456 F NP I N +S + + F G C G LAR+E + +L+ F Sbjct: 326 FFENPEIL----------NINRSPNRHISFGFGIHFCLGAPLARLEGHIAFKALLKRFPD 375 Query: 457 -NLKSVDDLKNLNTTAVTKGIVSLPPS 482 L D +G+ SLP S Sbjct: 376 IELAVAPDDIQWRKNVFLRGLESLPVS 402 >5L1U-A nrPDB Length = 401 Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 58/226 (25%), Positives = 91/226 (40%), Gaps = 37/226 (16%) Query: 265 DCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQ 324 D L ++ EKD S+ +I +L G LF G ETT + G LLLL++P A++ Sbjct: 206 DDILSELIAEKDGALSDADIAHL-GNAVLLF--GYETTIVRIDLGTLLLLRNPVQRAQLA 262 Query: 325 EEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTG----VPHAVTTDTKFRNYL 380 E+ P + A V EI R + G +P D + Sbjct: 263 ED----------PGL--------APAAVEEILRLG-VGGKGSNALIPRYAHGDITVGETV 303 Query: 381 IPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGL 440 I G +M + + +DD+ FP+ +FD ++ + F G R C G L Sbjct: 304 IRTGDAVMLAIGAANYDDRAFPDGGLFDLTRVRPRS--------HLAFGHGARHCIGRTL 355 Query: 441 ARMEL---FLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSY 483 AR+EL F L L + L ++ +T G +P ++ Sbjct: 356 ARIELTAVFERLFRRLPDLRLAVPEESLRWQEHRITGGFDEIPVTF 401 >1Z8P-A nrPDB Length = 404 Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 48/199 (24%), Positives = 81/199 (40%), Gaps = 31/199 (15%) Query: 258 NNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHP 317 P D + LI+++ + D + + + L L +AG E++ + + G LLL HP Sbjct: 205 TEPGDDLLSALIRVQDDDDGR---LSADELTSIALVLLLAGFESSVSLIGIGTYLLLTHP 261 Query: 318 EVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFR 377 + A V+ +D S +P V EI RY P + + Sbjct: 262 DQLALVR---------------RDPSALPNA---VEEILRYI-APPETTTRFAAEEVEIG 302 Query: 378 NYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAG 437 IP+ +T++ + D K+FP+P+ FD D G+ + F G C G Sbjct: 303 GVAIPQYSTVLVANGAANRDPKQFPDPHRFDVTR--DTRGH-------LSFGQGIHFCMG 353 Query: 438 EGLARMELFLFLTTILQNF 456 LA++E + L + F Sbjct: 354 RPLAKLEGEVALRALFGRF 372 >6F88-A nrPDB Length = 400 Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 49/182 (26%), Positives = 76/182 (41%), Gaps = 32/182 (17%) Query: 283 NIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDR 342 IE V L + G ETTS + + LL HP+ A+V+ QD Sbjct: 215 TIEASRQIVLSLILGGYETTSWLVANTIHALLAHPDTLARVR---------------QDP 259 Query: 343 SHMPYTDAVVHEIQRYSDLVPT--GVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKE 400 S +P A + E R+ P+ GV V D + + + GT + + +D+ Sbjct: 260 SLLP---AAIEEGMRW---CPSNFGVLRMVERDVRLDDQALSAGTVVCLAGIAGNYDETA 313 Query: 401 FPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF-NLK 459 +P+P ++D +D+ K F G C G LARME + L +L F L+ Sbjct: 314 YPSPEVYD----IDR----KPLPAANVFGGGAHFCVGAPLARMEARVGLQALLARFPGLR 365 Query: 460 SV 461 +V Sbjct: 366 AV 367 >5IT1-A nrPDB Length = 399 Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 58/229 (25%), Positives = 91/229 (39%), Gaps = 36/229 (15%) Query: 259 NPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPE 318 NP D + LI E + D + + N GT L +A +TT+ + G LLL P+ Sbjct: 203 NPGDDLISALITTE-DPDGVIDDMFLMNAAGT---LLIAAHDTTACMIGLGTALLLDRPD 258 Query: 319 VTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRN 378 A +Q++ +IG V E+ RY + G T D + Sbjct: 259 QLALLQKD-PSLIGN-----------------AVEELLRYLTIGQFGAERVATQDGEIGG 300 Query: 379 YLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGE 438 I KG ++ L S D +P FD ++ + F G C G+ Sbjct: 301 VRIAKGEQVVTHLLSADFDPAFVEDPERFD---------ITRRPAPHLAFGFGAHQCIGQ 351 Query: 439 GLARMELFLFLTTILQNFN----LKSVDDLKNLNTTAVTKGIVSLPPSY 483 LAR+EL + T+ + F K V++L+ N V G+ LP ++ Sbjct: 352 QLARIELQIVFGTLFRRFPTLRLAKPVEELRFRNDM-VFYGVHELPVTW 399 >5Z9I-A nrPDB Length = 398 Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 50/204 (24%), Positives = 81/204 (39%), Gaps = 37/204 (18%) Query: 241 RSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTE 300 R Y E+ E + PR+ + L+ E D QK N + L V G Sbjct: 190 RDYWHERAAESR-----KRPREDLISQLV--HAEVDGQK--LNDSQISNIANRLLVNGHL 240 Query: 301 TTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSD 360 TT+ + +L L + A+V+ DRS +P A++ E RY Sbjct: 241 TTAMLIANTMLCLDAFSDQDARVR---------------ADRSLVP---ALLEESMRYMS 282 Query: 361 LVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFK 420 + GV A ++ + +IPK ++ + D+++F P++FD G + Sbjct: 283 PI-CGVGRATNSEVEVAGTVIPKDQLLLVWTGAANRDERQFEKPDVFDAG---------R 332 Query: 421 KSDYFMPFSAGKRICAGEGLARME 444 + + F G C G LARME Sbjct: 333 SPNAHLGFGRGIHFCLGRQLARME 356 >3MGX-A nrPDB Length = 415 Score = 48.5 bits (114), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 35/132 (26%), Positives = 55/132 (41%), Gaps = 10/132 (7%) Query: 349 DAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFD 408 D VV E+ R++ V T D +P GT ++A L + D EF +P+ F Sbjct: 288 DTVVEEVLRWTSPA-MHVLRVTTADVTINGRDLPSGTPVVAWLPAANRDPAEFDDPDTFL 346 Query: 409 PGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLN 468 PG +K + + F G C G LAR+EL + L + + + ++ Sbjct: 347 PG---------RKPNRHITFGHGMHHCLGSALARIELSVVLRVLAERVSRVDLEREPAWL 397 Query: 469 TTAVTKGIVSLP 480 V +G LP Sbjct: 398 RAIVVQGYRELP 409 >5LIV-A nrPDB Length = 450 Score = 48.5 bits (114), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 49/182 (26%), Positives = 76/182 (41%), Gaps = 32/182 (17%) Query: 283 NIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDR 342 IE V L + G ETTS + + LL HP+ A+V+ QD Sbjct: 265 TIEASRQIVLSLILGGYETTSWLVANTIHALLAHPDTLARVR---------------QDP 309 Query: 343 SHMPYTDAVVHEIQRYSDLVPT--GVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKE 400 S +P A + E R+ P+ GV V D + + + GT + + +D+ Sbjct: 310 SLLP---AAIEEGMRW---CPSSFGVLRMVERDVRLDDQALSAGTVVCLAGIAGNYDETA 363 Query: 401 FPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF-NLK 459 +P+P ++D +D+ K F G C G LARME + L +L F L+ Sbjct: 364 YPSPEVYD----IDR----KPLPAANVFGGGAHFCVGAPLARMEARVGLQALLARFPGLR 415 Query: 460 SV 461 +V Sbjct: 416 AV 417 >3P3Z-A nrPDB Length = 416 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 41/170 (24%), Positives = 65/170 (38%), Gaps = 29/170 (17%) Query: 276 DNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHR 335 D ++ + LV TV VAG ETT+ L + +HP+ K++E Sbjct: 235 DGVLDDYELRTLVATV---LVAGYETTNHQLALAMYDFAQHPDQWMKIKE---------- 281 Query: 336 SPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVL 395 +P + ++ V E+ R+S +P D + IP GT + Sbjct: 282 NPELAPQA--------VEEVLRWSPTLPVTATRVAAEDFEVNGVRIPTGTPVFMCAHVAH 333 Query: 396 HDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMEL 445 D + F + + FD K+ + F G C G LAR+EL Sbjct: 334 RDPRVFADADRFDI--------TVKREAPSIAFGGGPHFCLGTALARLEL 375 >6FSH-A nrPDB Length = 398 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 52/242 (21%), Positives = 94/242 (38%), Gaps = 33/242 (13%) Query: 241 RSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTE 300 R+ + +K + ++ +D D F+ + E + ++ E L G L +AG + Sbjct: 183 RAALGDKFSRYLLAMIARERKDPGDGFIGSIVAEHGDTITD---EELRGVCVQLMLAGDD 239 Query: 301 TTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSD 360 S + G+L LL+HPE A ++ + D+S D V E+ RY Sbjct: 240 NVSGMIGLGVLALLRHPEQIAALRGD--------------DQS----ADRAVDELIRYLT 281 Query: 361 LVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFK 420 + P D + +I +G T++ L D P+ + D + Sbjct: 282 VPYAPTPRTAVEDVMVADQVIKEGETVLCSLPMANRDRALLPDADRLD---------VTR 332 Query: 421 KSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF-NLKSVDDLKNL--NTTAVTKGIV 477 + F G C G L R++L + T + + F L+ D + + T+ G+ Sbjct: 333 TPVPHVAFGHGIHHCLGAALTRLQLRIAYTALWRRFPALQLADPAQEIMFRTSTPAYGLT 392 Query: 478 SL 479 SL Sbjct: 393 SL 394 >1CPT-A nrPDB Length = 428 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 60/252 (23%), Positives = 102/252 (40%), Gaps = 43/252 (17%) Query: 222 LIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQ-EKDNQKS 280 L F G H + VA R E + + + D+ + F + KD+ S Sbjct: 183 LTQDFFGVHEPDEQAVAAPRQSADEAARRFHET--IATFYDYFNGFTVDRRSCPKDDVMS 240 Query: 281 EFNIENLVGTVAD----------LFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHV 330 L G D + AG +TTS++ ++ L ++PE A + + Sbjct: 241 LLANSKLDGNYIDDKYINAYYVAIATAGHDTTSSSSGGAIIGLSRNPEQLALAKSD---- 296 Query: 331 IGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMAL 390 P + R +V E R++ V + + A+ DT+ R I +G IM Sbjct: 297 ------PALIPR--------LVDEAVRWTAPVKSFMRTALA-DTEVRGQNIKRGDRIMLS 341 Query: 391 LTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLT 450 S D++ F NP+ FD F +++ + F G +C G+ LA++E+ +F Sbjct: 342 YPSANRDEEVFSNPDEFDITRFPNRH---------LGFGWGAHMCLGQHLAKLEMKIFFE 392 Query: 451 TILQNFNLKSVD 462 +L LKSV+ Sbjct: 393 ELLP--KLKSVE 402 >1EHE-A nrPDB Length = 403 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 48/190 (25%), Positives = 76/190 (40%), Gaps = 28/190 (14%) Query: 294 LFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVH 353 L VAG T + G+ L +HP+ A+++ +P + + V Sbjct: 236 LLVAGNATMVNMIALGVATLAQHPDQLAQLKA----------NPSLAPQ--------FVE 277 Query: 354 EIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFL 413 E+ RY + D + L+ I+A S D++ F NP+ F Sbjct: 278 ELCRYHTASALAIKRTAKEDVMIGDKLVRANEGIIASNQSANRDEEVFENPDEF------ 331 Query: 414 DKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF-NLKSVDDLKNLNTTAV 472 + N + D + F G C E LA+ EL +T+ Q F +LK L +N T + Sbjct: 332 NMNRKWPPQDP-LGFGFGDHRCIAEHLAKAELTTVFSTLYQKFPDLKVAVPLGKINYTPL 390 Query: 473 TK--GIVSLP 480 + GIV LP Sbjct: 391 NRDVGIVDLP 400 >4TX3-A nrPDB Length = 404 Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 53/245 (21%), Positives = 93/245 (37%), Gaps = 33/245 (13%) Query: 238 ALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVA 297 A R+ E + ++ +D D F+ + E + ++ E L G L +A Sbjct: 186 ARKRAAAGEAFARYLVAMMARERKDPGDGFIGSIVAEHGDTITD---EELRGVCVQLMLA 242 Query: 298 GTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQR 357 G + S + G+L LL+HPE A ++ + D+S D V E+ R Sbjct: 243 GDDNVSGMIGLGVLALLRHPEQIAALRGD--------------DQS----ADRAVDELIR 284 Query: 358 YSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNG 417 Y + P D + +I +G T++ L D P+ + D Sbjct: 285 YLTVPYAPTPRTAVEDVMVADQVIKEGETVLCSLPMANRDRALLPDADRLD--------- 335 Query: 418 NFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF-NLKSVDDLKNL--NTTAVTK 474 + + F G C G L R++L + T + + F L+ D + + T+ Sbjct: 336 VTRTPVPHVAFGHGIHHCLGAALTRLQLRIAYTALWRRFPALQLADPAQEIMFRTSTPAY 395 Query: 475 GIVSL 479 G+ SL Sbjct: 396 GLTSL 400 >4WMZ-A nrPDB Length = 539 Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 56/239 (23%), Positives = 105/239 (43%), Gaps = 27/239 (11%) Query: 238 ALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQK-SEFNIENLVGTVADLFV 296 A++ +Y+ +KE + + D+ + RD ID L+K KD K ++ I NL+ V + Sbjct: 260 AISGTYM-SLIKERRKNNDIQD-RDLIDS-LMKNSTYKDGVKMTDQEIANLLIGV---LM 313 Query: 297 AGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDR-SHMPYTDAVVHEI 355 G T++ T + LL L + P+V ++ EE V+ + D MP + + E Sbjct: 314 GGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLDGGKKELTYDLLQEMPLLNQTIKET 373 Query: 356 QRYSDLVPTGVPHAVTTDTKFRN--YLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFL 413 R + + + V D N Y+IP G ++ D+ FPN + F+ + Sbjct: 374 LRMHHPLHS-LFRKVMKDMHVPNTSYVIPAGYHVLVSPGYTHLRDEYFPNAHQFNIHRWN 432 Query: 414 DKNGNF----KKSDY------------FMPFSAGKRICAGEGLARMELFLFLTTILQNF 456 + + + ++ DY ++PF G+ C GE A +L + ++ ++ Sbjct: 433 NDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAYCQLGVLMSIFIRTL 491 >2XKR-A nrPDB Length = 398 Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 57/235 (24%), Positives = 94/235 (40%), Gaps = 41/235 (17%) Query: 259 NPRDFIDCFLIKMEQEKDN-QKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHP 317 +P D + L+ E + + E +E L+ + + G ETT TL G LL++ Sbjct: 196 DPTDDLVSVLVSSEVDGERLSDDELVMETLL-----ILIGGDETTRHTLSGGTEQLLRNR 250 Query: 318 EVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFR 377 + +Q +D S +P + E+ R++ V + +T DT+F Sbjct: 251 DQWDLLQ---------------RDPSLLP---GAIEEMLRWTAPV-KNMCRVLTADTEFH 291 Query: 378 NYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAG 437 + G +M L S D+ F P FD + +N N + F G C G Sbjct: 292 GTALCAGEKMMLLFESANFDEAVFCEPEKFD----VQRNPN-----SHLAFGFGTHFCLG 342 Query: 438 EGLARMELFLFLTTILQ---NFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIP 489 LAR+EL L +L+ + L + D + L G+ S+P + F P Sbjct: 343 NQLARLELSLMTERVLRRLPDLRLVADDSVLPLRPANFVSGLESMP----VVFTP 393 >4MM0-A nrPDB Length = 399 Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 84/391 (21%), Positives = 148/391 (37%), Gaps = 73/391 (18%) Query: 72 NPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGL--GIISSNGKRWKEIRRFSLT 129 +P + YE V+ L D FS R + P + R+T+ +++++ +RR Sbjct: 45 DPGFLVTRYEDVRFVLSD--PRFSVRQDLPGAPRLTEMTFESVMTTDPPVHTRLRRL--- 99 Query: 130 TLRNFGMGKRSIE---DRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNVICSVVFQK 185 R+F R IE R++E A L++E+ K K +P D L P VIC Sbjct: 100 LSRDFT--ARRIERMRPRLEEIAEGLLDEMEK-KGAPADIVESLAVPFPITVICE----- 151 Query: 186 RFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIR 245 +L P + V F D +++ R + Sbjct: 152 ---------------------LLGVPMVDVAR-FRGWADTMVSLTGYSMEDWTAARDALE 189 Query: 246 EKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTT 305 + A+ N D + + + DN+ ++ ++ +L L +AG E S Sbjct: 190 SYLDGLVAAKRENPGSDLLSALVATAAE--DNELTDHDVRSLSLI---LLLAGYEPASNQ 244 Query: 306 LRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTG 365 L +L LL+ P+ A+++ R P + +P + V E+ RY+ Sbjct: 245 LGSSVLTLLRFPDRLAELR----------RDPGL-----LP---SAVEELMRYAPAGDGA 286 Query: 366 VPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYF 425 + D + IP + ++A + D + F +P G LD+ N + Sbjct: 287 LFRVTLEDVTIGDTHIPANSAVLASTQAANWDPRRFDDPT----GLRLDRPDNQHTA--- 339 Query: 426 MPFSAGKRICAGEGLARMELFLFLTTILQNF 456 G C G LAR+EL + + +L+ F Sbjct: 340 --LGHGIHFCLGAALARVELQVAIGALLRRF 368 >3JUS-A nrPDB Length = 461 Score = 45.4 bits (106), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 41/179 (22%), Positives = 71/179 (39%), Gaps = 2/179 (1%) Query: 285 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDR-S 343 + + G + L +AG T+STT + L + + K E V G + P D+ Sbjct: 251 DEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYDQLK 310 Query: 344 HMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPN 403 + D + E R + + A T T Y IP G + T + Sbjct: 311 DLNLLDRCIKETLRLRPPIMIMMRMARTPQT-VAGYTIPPGHQVCVSPTVNQRLKDSWVE 369 Query: 404 PNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVD 462 F+P +L N + ++PF AG+ C GE A +++ +T+L+ + +D Sbjct: 370 RLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLID 428 >5NWS-A nrPDB Length = 435 Score = 45.4 bits (106), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 40/194 (20%), Positives = 79/194 (40%), Gaps = 23/194 (11%) Query: 263 FIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAK 322 D L ++ + +D+ + V + L +AG ET++ + G LL HP A Sbjct: 233 LTDDLLSELIRAQDDDGGRLSDIETVTMILTLVLAGHETSAHLIGNGTAALLTHPGQWAL 292 Query: 323 VQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIP 382 ++++ P + R+ VHE+ R+ V T D + + Sbjct: 293 LRKD----------PALLPRA--------VHELMRWCGSVHVARLRYATEDLELAGTPVA 334 Query: 383 KGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLAR 442 +G + +L S D + + +P+ D + ++ + ++ + F G C G LAR Sbjct: 335 RGDAVQLVLVSANFDPRHYSDPDRLD----ITRHQEGQAENH-VGFGHGIHYCLGATLAR 389 Query: 443 MELFLFLTTILQNF 456 E + L +L+ + Sbjct: 390 QEGEVALARLLETY 403 >3A50-A nrPDB Length = 411 Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 45/180 (25%), Positives = 60/180 (33%), Gaps = 27/180 (15%) Query: 265 DCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQ 324 D L + D + E LV L +AG ETT + G+L LL HP+ Sbjct: 204 DALLSSLLAVSDMDGDRLSQEELVAMAMLLLIAGHETTVNLIGNGVLALLTHPD------ 257 Query: 325 EEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKG 384 R +D S + V E R+ V D + IP G Sbjct: 258 ---------QRKLLAEDPS---LISSAVEEFLRFDSPVSQAPIRFTAEDVTYSGVTIPAG 305 Query: 385 TTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARME 444 +M L + D P P+ D D +G F G C G LAR+E Sbjct: 306 EMVMLGLAAANRDADWMPEPDRLDITR--DASGGVF-------FGHGIHFCLGAQLARLE 356 >5JLC-A nrPDB Length = 515 Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 60/265 (22%), Positives = 115/265 (43%), Gaps = 31/265 (11%) Query: 238 ALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQK-SEFNIENLVGTVADLFV 296 A++ +Y+ +KE + D+ N RD ID L+K KD K ++ I NL+ V + Sbjct: 242 AISGTYM-SLIKERREKNDIQN-RDLIDE-LMKNSTYKDGTKMTDQEIANLLIGV---LM 295 Query: 297 AGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRH-RSPCMQDRSHMPYTDAVVHEI 355 G T++ T + LL L + P+V ++ +E V+ + D +MP + ++ E Sbjct: 296 GGQHTSAATSAWCLLHLAERPDVQEELYQEQMRVLNNDTKELTYDDLQNMPLLNQMIKET 355 Query: 356 QRYSDLVPTGVPHAVTTDTKFRN--YLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFL 413 R + + + V D N Y++P+ ++ ++ FP PN F+ H Sbjct: 356 LRLHHPLHS-LFRKVMRDVAIPNTSYVVPRDYHVLVSPGYTHLQEEFFPKPNEFNI-HRW 413 Query: 414 DKNGNFKKS------DY------------FMPFSAGKRICAGEGLARMELFLFLTTILQN 455 D + + DY ++PF G+ C GE A +L + ++ ++ Sbjct: 414 DGDAASSSAAGGDEVDYGFGAISKGVSSPYLPFGGGRHRCIGELFAYCQLGVLMSIFIRT 473 Query: 456 FNLKSVDDLKNLNTTAVTKGIVSLP 480 + + + + + T +V+LP Sbjct: 474 MKWRYPTEGETVPPSDFT-SMVTLP 497 >1WIY-A nrPDB Length = 389 Score = 44.7 bits (104), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 44/180 (24%), Positives = 71/180 (39%), Gaps = 25/180 (13%) Query: 280 SEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCM 339 S E + L VAG ET ++ L + LLL P+ +V E + + Sbjct: 204 SHLPRERALSEAVTLLVAGHETVASALTWSFLLLSHRPDWQKRVAESEEAALA-----AF 258 Query: 340 QDRSHM-PYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDD 398 Q+ + P + ++R P + D +P+GTT++ L+ + Sbjct: 259 QEALRLYPPAWILTRRLER---------PLLLGEDR------LPQGTTLV--LSPYVTQR 301 Query: 399 KEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNL 458 FP F P FL + G S + PF G+R+C G A +E + L + F L Sbjct: 302 LYFPEGEAFQPERFLAERGT--PSGRYFPFGLGQRLCLGRDFALLEGPIVLRAFFRRFRL 359 >2RFC-A nrPDB Length = 343 Score = 44.7 bits (104), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 41/163 (25%), Positives = 68/163 (41%), Gaps = 15/163 (9%) Query: 301 TTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSD 360 T ++Y +LL++ E T + + VI +P + D + + V E RY Sbjct: 174 TMDEKIKYIMLLIIGGNETTTNLIGNMIRVIDE--NPDIIDDA-LKNRSGFVEETLRYYS 230 Query: 361 LVPTGVPHA-VTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNF 419 + +PH D+ N I KG ++ L S D+ F P++F G Sbjct: 231 PIQF-LPHRFAAEDSYINNKKIKKGDQVIVYLGSANRDETFFDEPDLFKIG--------- 280 Query: 420 KKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVD 462 + + + F G +C G LAR+E + L IL +F +D Sbjct: 281 -RREMHLAFGIGIHMCLGAPLARLEASIALNDILNHFKRIKID 322 >6A7I-A nrPDB Length = 411 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 44/200 (22%), Positives = 80/200 (40%), Gaps = 32/200 (16%) Query: 258 NNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHP 317 NP D + LI + D+ E +V T+ + AG ETT + + + L HP Sbjct: 205 TNPGDDLTSALIAASENGDH----LTDEEIVNTLQLIIAAGHETTISLIVNVVEALQTHP 260 Query: 318 EVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFR 377 E KV ++ IG D V+ E R++ + T D + Sbjct: 261 EQRKKV---LNGEIG---------------WDGVIEETLRWNTPTSHVLIRFATEDIEVG 302 Query: 378 NYLIPKGTTIMALLTSVLHDDKEF-PNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICA 436 + ++PKG ++ ++ D++++ P FD + + + F G +C Sbjct: 303 DKILPKGEGLIISFGALGRDEEQYGPTAGEFD---------ATRTPNRHIAFGHGPHVCP 353 Query: 437 GEGLARMELFLFLTTILQNF 456 G L+R+E + L + + F Sbjct: 354 GAALSRLEAGIALPALYERF 373 >5OFQ-A nrPDB Length = 409 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 57/247 (23%), Positives = 92/247 (37%), Gaps = 45/247 (18%) Query: 224 DCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFN 283 + F K + V + Y +E + E Q N D I L E E D + Sbjct: 177 EAFAKMMQKRNEGVIFLQGYFKEIIAERQQ----NKQEDLISLLL---EAEIDGE--HLT 227 Query: 284 IENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRS 343 E ++G L VAG ETT+ + G+ + + +V +V+ +I V Sbjct: 228 EEEVLGFCILLLVAGNETTTNLITNGVRYMTEDVDVQNEVRRDISLVPN----------- 276 Query: 344 HMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPN 403 +V E RY + + D + I +G +++ S D +F Sbjct: 277 -------LVEETLRYYPPI-QAIGRIAAEDVELGECKIKRGQQVISWAASANRDSAKFEW 328 Query: 404 PNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTIL--------QN 455 P+ F +K++ + F G C G LARME + T +L QN Sbjct: 329 PDTFVV---------HRKTNPHVSFGFGIHFCLGAPLARMEGKIAFTKLLEKGGFSKVQN 379 Query: 456 FNLKSVD 462 +LK +D Sbjct: 380 QSLKPID 386 >5Y1I-A nrPDB Length = 403 Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 67/313 (21%), Positives = 110/313 (35%), Gaps = 60/313 (19%) Query: 174 PCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKV 233 P VIC ++ Y+D+ FL Q NN + D G K Sbjct: 148 PVRVICEMLG---VPYEDREFL------------------QQNNNAMIYRDTAQGDAQKA 186 Query: 234 LKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVAD 293 A+ Y++E V + D + +++E E ++ G Sbjct: 187 AIAQAM---YLKELVGTKLG----DRGDDILSDLAVQVE------AGEITQDDAAGIGMM 233 Query: 294 LFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVH 353 L AG ETT+ + G L LL++PE A+V++ D + + V Sbjct: 234 LLGAGHETTANMIALGTLALLENPEQLAEVRDSDDPKVIVN----------------TVE 277 Query: 354 EIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFL 413 E+ RY + V D + +I G I+ L + D +P P Sbjct: 278 ELLRYLTIAQDTVRRIAAEDIEIGGVVIKAGEGIVFPLNAANWDPDLYPEA----PDRLD 333 Query: 414 DKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQ---NFNLKSVDDLKNLNTT 470 N ++ + F G C G LAR+EL + +T+L+ L D Sbjct: 334 IHRANARR---HLAFGYGVHQCLGATLARVELQIVYSTLLRRIPTLALAGTLDEIPFKHD 390 Query: 471 AVTKGIVSLPPSY 483 + G+ LP ++ Sbjct: 391 QIAHGVYELPVTW 403 >2IJ7-A nrPDB Length = 396 Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 40/182 (21%), Positives = 69/182 (37%), Gaps = 26/182 (14%) Query: 275 KDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRH 334 KD S + E F AG +T + L L+ L++ P++ + E+ + + Sbjct: 211 KDPAYSHVSDELFATIGVTFFGAGVISTGSFLTTALISLIQRPQLRNLLHEKPELI---- 266 Query: 335 RSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSV 394 A V E+ R + G+P T D + + L+ KG ++ LL Sbjct: 267 --------------PAGVEELLRINLSFADGLPRLATADIQVGDVLVRKGELVLVLLEGA 312 Query: 395 LHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQ 454 D + FPNP + LD+ + F G+ C G L R + + +L+ Sbjct: 313 NFDPEHFPNPGSIE----LDR----PNPTSHLAFGRGQHFCPGSALGRRHAQIGIEALLK 364 Query: 455 NF 456 Sbjct: 365 KM 366 >3ABA-A nrPDB Length = 403 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 58/233 (24%), Positives = 94/233 (40%), Gaps = 42/233 (18%) Query: 259 NPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPE 318 NP D + LI E + D + + N GT L +A +TT+ + G LLL P+ Sbjct: 203 NPGDDLISALITTE-DPDGVVDDMFLMNAAGT---LLIAAHDTTACMIGLGTALLLDSPD 258 Query: 319 VTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRN 378 A ++E+ P + + V E+ RY + G T D + Sbjct: 259 QLALLRED----------PSLVGNA--------VEELLRYLTIGQFGGERVATRDVELGG 300 Query: 379 YLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNF---KKSDYFMPFSAGKRIC 435 I KG ++A VL D FDP F+++ F ++ + F G C Sbjct: 301 VRIAKGEQVVA---HVLAAD--------FDPA-FVEEPERFDITRRPAPHLAFGFGAHQC 348 Query: 436 AGEGLARMELFLFLTTILQNFN----LKSVDDLKNLNTTAVTKGIVSLPPSYQ 484 G+ LAR+EL + T+ + K V++L+ V G+ LP ++ Sbjct: 349 IGQQLARIELQIVFETLFRRLPGLRLAKPVEELR-FRHDMVFYGVHELPVTWH 400 >6GII-A nrPDB Length = 479 Score = 42.7 bits (99), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 40/159 (25%), Positives = 59/159 (37%), Gaps = 27/159 (16%) Query: 294 LFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVH 353 + VA ETT L LL+H V ++ C D S +P A Sbjct: 305 IIVAAHETTVFATTNALKTLLEHETVWREI--------------CA-DPSLIP---AAAE 346 Query: 354 EIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFL 413 E RY+ V G T + + +P G I+ ++ S HD F +P FD G Sbjct: 347 ECLRYNGPV-AGWRRRTTREVEVEGVRLPVGANILMVVASANHDSAHFDDPEFFDIGR-- 403 Query: 414 DKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTI 452 + + F G C G L RME+ + + + Sbjct: 404 ------SNASEHLNFGYGAHQCLGRNLGRMEMQIMIEEL 436 >5YHJ-A nrPDB Length = 413 Score = 42.7 bits (99), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 34/117 (29%), Positives = 54/117 (46%), Gaps = 14/117 (11%) Query: 330 VIGRHRSPCMQD---RSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTT 386 V+ H+ P +++ R + T+ V E++R+ P V TD ++ Y P+GT Sbjct: 252 VLALHQFPDVKEQVERGEVSKTE-FVQEVRRFYPFFPVAAAR-VKTDFEWDGYAFPEGTL 309 Query: 387 IMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDY-FMPFSAGK----RICAGE 438 + L HD + P+ FDP F D +K+S + F+P G CAGE Sbjct: 310 TLLDLYGTNHDVSIWTEPDRFDPSRFKD----WKESPFNFIPQGGGDVDFGHRCAGE 362 >1UED-A nrPDB Length = 406 Score = 42.7 bits (99), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 41/172 (23%), Positives = 64/172 (37%), Gaps = 27/172 (15%) Query: 285 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSH 344 E L G L + G ET + + +G+L LL +P + E SP +R Sbjct: 233 EELKGLCTALILGGVETVAGMIGFGVLALLDNPGQIELLFE----------SPEKAER-- 280 Query: 345 MPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNP 404 VV+E+ RY V P D LI G ++ + D+ P+P Sbjct: 281 ------VVNELVRYLSPVQAPNPRLAIKDVVIDGQLIKAGDYVLCSILMANRDEALTPDP 334 Query: 405 NIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF 456 ++ D + + + F G C G LAR L + T+ + F Sbjct: 335 DVLDAN---------RAAVSDVGFGHGIHYCVGAALARSMLRMAYQTLWRRF 377 >6A7J-A nrPDB Length = 411 Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 41/199 (20%), Positives = 80/199 (40%), Gaps = 32/199 (16%) Query: 259 NPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPE 318 NP D + LI ++ D+ E ++ T+ + AG ETT + + + L HPE Sbjct: 206 NPGDDLTSALIAASEDGDH----LTDEEILNTLQLIIAAGHETTISLIVNVVEALAIHPE 261 Query: 319 VTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRN 378 KV +P+ + V+ E R++ + T D + + Sbjct: 262 QRKKVLS-----------------GEIPW-EGVIEETLRWNTPTSHVLIRFATEDIEVGD 303 Query: 379 YLIPKGTTIMALLTSVLHDDKEF-PNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAG 437 ++PKG ++ ++ D++++ P FD + + + F G +C G Sbjct: 304 KVLPKGEGLVVSFGALGRDEEQYGPTAGDFD---------ATRTPNRHIAFGHGPHVCPG 354 Query: 438 EGLARMELFLFLTTILQNF 456 L+R+E + L + + F Sbjct: 355 AALSRLEAGIALPALYERF 373 >2WIO-A nrPDB Length = 431 Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 52/225 (23%), Positives = 85/225 (37%), Gaps = 43/225 (19%) Query: 242 SYIREKVKEHQASLDVNNPRDFIDCFLIKMEQE----KDNQKSEFNIENLVGTVADLFVA 297 +Y++ + E +A +P D + L+ E + D + + F+ L +A Sbjct: 215 AYLKARCAERRA-----DPGDDLISRLVLAEVDGRALDDEEAANFSTA--------LLLA 261 Query: 298 GTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQR 357 G TT+ L + L +HP H +D +P A+V E+ R Sbjct: 262 GHITTTVLLGNIVRTLDEHPA---------------HWDAAAEDPGRIP---AIVEEVLR 303 Query: 358 YSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNG 417 Y P + T T+ IP + + S D +P+ FDP K+G Sbjct: 304 YRPPFPQ-MQRTTTKATEVAGVPIPADVMVNTWVLSANRDSDAHDDPDRFDPSR---KSG 359 Query: 418 NFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVD 462 + + F G C G LAR+E + L I+ F +VD Sbjct: 360 GAAQ----LSFGHGVHFCLGAPLARLENRVALEEIIARFGRLTVD 400 >6CVC-A nrPDB Length = 433 Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 36/152 (23%), Positives = 57/152 (37%), Gaps = 26/152 (17%) Query: 294 LFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVH 353 L VAG ETT + +G+L L ++P+ AK + D + V Sbjct: 268 LVVAGNETTRNAISHGMLALSRYPDERAKWWSDFDGLAA-----------------TAVE 310 Query: 354 EIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFL 413 EI R++ V + ++ D R + G + S D+++F +P FD Sbjct: 311 EIVRWASPV-VYMRRTLSQDVDLRGTKMAAGDKVTLWYCSANRDEEKFADPWTFDVTRNP 369 Query: 414 DKNGNFKKSDYFMPFSAGKRICAGEGLARMEL 445 + F G C G LAR E+ Sbjct: 370 NPQVGFG--------GGGAHFCLGANLARREI 393 >2WM5-A nrPDB Length = 435 Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 39/152 (25%), Positives = 61/152 (40%), Gaps = 26/152 (17%) Query: 294 LFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVH 353 L VAG ETT + +G+L L ++PE + + D + +P V Sbjct: 271 LVVAGNETTRNAITHGVLALSRYPEQRDRWWSDFDGL-----APT------------AVE 313 Query: 354 EIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFL 413 EI R++ V + +T D + R + G + S D+ +F +P FD L Sbjct: 314 EIVRWASPV-VYMRRTLTQDIELRGTKMAAGDKVSLWYCSANRDESKFADPWTFD----L 368 Query: 414 DKNGNFKKSDYFMPFSAGKRICAGEGLARMEL 445 +N N + G C G LAR E+ Sbjct: 369 ARNPN----PHLGFGGGGAHFCLGANLARREI 396 >5FYF-A nrPDB Length = 470 Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 46/201 (22%), Positives = 86/201 (42%), Gaps = 33/201 (16%) Query: 287 LVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMP 346 +G + L V G +TT ++ GL+ + + P K++ + + + P M Sbjct: 297 FIGNLTLLIVGGNDTTRNSMSGGLVAMNEFPREFEKLKAKPELI------PNM------- 343 Query: 347 YTDAVVHEIQRYSDLVPTGVPHAVT-TDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPN 405 V EI R+ P + D + I KG ++ S D+++F NP+ Sbjct: 344 -----VSEIIRWQ--TPLAYMRRIAKQDVELGGQTIKKGDRVVMWYASGNRDERKFDNPD 396 Query: 406 IFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF-NLKSVDDL 464 F +D+ K + M F G C G LA ++L + IL+ F N++ V++ Sbjct: 397 QF----IIDR----KDARNHMSFGYGVHRCMGNRLAELQLRILWEEILKRFDNIEVVEEP 448 Query: 465 KNLNTTAV---TKGIVSLPPS 482 + + + V ++ +V L P+ Sbjct: 449 ERVQSNFVRGYSRLMVKLTPN 469 >5GWE-A nrPDB Length = 405 Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 46/191 (24%), Positives = 75/191 (39%), Gaps = 31/191 (16%) Query: 262 DFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTA 321 D + L++ +QE E + + L AG ETT+T + +LL HPE Sbjct: 211 DNLTADLVRAQQEG----QEITDHEIASLLYSLLFAGHETTTTLISNCFRVLLDHPEQWQ 266 Query: 322 KVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLI 381 + E +P + +P A V E+ RYS + G DT+ I Sbjct: 267 AILE----------NPKL-----IP---AAVDEVLRYSGSI-VGWRRKALKDTEIGGVAI 307 Query: 382 PKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLA 441 +G ++ L+ S D+ F N FD N ++ + F G C G LA Sbjct: 308 KEGDGVLLLMGSANRDEARFENGEEFDI-----SRANARE---HLSFGFGIHYCLGNMLA 359 Query: 442 RMELFLFLTTI 452 +++ + L + Sbjct: 360 KLQAKICLEEV 370 >5XW2-A nrPDB Length = 419 Score = 41.6 bits (96), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 53/212 (25%), Positives = 84/212 (39%), Gaps = 35/212 (16%) Query: 246 EKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTT 305 E ++EH A PR + LI E E D ++ N ++V L +AG TT+ Sbjct: 210 EYLREHAAECR-RRPRGDLMGKLI--EAEVDGRRLTDN--HIVNFAKMLLIAGYLTTTML 264 Query: 306 LRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTG 365 + +L L +PE A+V+ DRS +P ++ E R+ L P Sbjct: 265 IGNTVLCLDSYPEQAARVR---------------ADRSLIP---GLLEESMRF--LSPVA 304 Query: 366 VPHAVTT-DTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDY 424 + TT D + + +M + D ++F P +FD + + Sbjct: 305 ATYRATTRDVEVAGQRLSADQMVMVWFGAANRDARQFAEPELFD---------MTRGPNP 355 Query: 425 FMPFSAGKRICAGEGLARMELFLFLTTILQNF 456 + F G C G LARME + L +L F Sbjct: 356 HLGFGRGIHFCLGGPLARMEGRVALDHLLDRF 387 >5XJN-A nrPDB Length = 455 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 46/191 (24%), Positives = 75/191 (39%), Gaps = 31/191 (16%) Query: 262 DFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTA 321 D + L++ +QE E + + L AG ETT+T + +LL HPE Sbjct: 261 DNLTADLVRAQQEG----QEITDHEIASLLYSLLFAGHETTTTLISNCFRVLLDHPEQWQ 316 Query: 322 KVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLI 381 + E +P + +P A V E+ RYS + G DT+ I Sbjct: 317 AILE----------NPKL-----IP---AAVDEVLRYSGSI-VGWRRKALKDTEIGGVAI 357 Query: 382 PKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLA 441 +G ++ L+ S D+ F N FD N ++ + F G C G LA Sbjct: 358 KEGDGVLLLMGSANRDEARFENGEEFDI-----SRANARE---HLSFGFGIHYCLGNMLA 409 Query: 442 RMELFLFLTTI 452 +++ + L + Sbjct: 410 KLQAKICLEEV 420 >4YT3-A nrPDB Length = 410 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 59/231 (25%), Positives = 96/231 (41%), Gaps = 44/231 (19%) Query: 259 NPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLL-LLLKHP 317 NP D I L+K E + + F + +V T + AG ETTS L LL Sbjct: 209 NPADDIISDLLKSEVDGEM----FTDDEVVRTTMLILGAGVETTSHLLANSFYSLLYDDK 264 Query: 318 EVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYS-DLVPTGVPHAVTTDTKF 376 EV ++ E +D V V E+ R+ +L+ + V D Sbjct: 265 EVYQELHENLDLV------------------PQAVEEMLRFRFNLI--KLDRTVKEDNDL 304 Query: 377 RNYLIPKGTTIMALLTSVLHDDKEFPNP---NIFDPGHFLDKNGNFKKSDYFMPFSAGKR 433 + +G +++ +++ D++ F +P NI P N KK + F G Sbjct: 305 LGVELKEGDSVVVWMSAANMDEEMFEDPFTLNIHRP--------NNKKH---LTFGNGPH 353 Query: 434 ICAGEGLARMELFLFLTTILQNF-NLKSVDDLK---NLNTTAVTKGIVSLP 480 C G LAR+E + LT L+ F ++++V + NL +A + + SLP Sbjct: 354 FCLGAPLARLEAKIALTAFLKKFKHIEAVPSFQLEENLTDSATGQTLTSLP 404 >6FYJ-A nrPDB Length = 421 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 12/98 (12%) Query: 347 YTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNI 406 Y+ V E++R+ P V V D ++ Y +GT + L HD + + NP++ Sbjct: 279 YSQMFVQEVRRFYPFFPFVVA-LVKKDFTWKGYKFEEGTLTLLDLYGTNHDPEIWKNPDV 337 Query: 407 FDPGHFLDKNGN------FKKSDYFMPFSAGKRICAGE 438 F P F G+ DYFM G R CAGE Sbjct: 338 FSPDRFAKWEGSPFSFIPQGGGDYFM----GHR-CAGE 370 >1LG9-A nrPDB Length = 398 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 40/172 (23%), Positives = 65/172 (37%), Gaps = 27/172 (15%) Query: 285 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSH 344 E L G + +AG + S + G+L +L+HP E+ID G +S Sbjct: 224 EELRGFCVQVMLAGDDNISGMIGLGVLAMLRHP-------EQIDAFRGDEQS-------- 268 Query: 345 MPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNP 404 V E+ RY + + P D I KG +++ L + D P+ Sbjct: 269 ---AQRAVDELIRYLTVPYSPTPRIAREDLTLAGQEIKKGDSVICSLPAANRDPALAPD- 324 Query: 405 NIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF 456 +D+ ++ + F G C G LAR+EL T + + F Sbjct: 325 --------VDRLDVTREPIPHVAFGHGVHHCLGAALARLELRTVFTELWRRF 368 >5XNT-A nrPDB Length = 411 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 60/231 (25%), Positives = 95/231 (41%), Gaps = 44/231 (19%) Query: 259 NPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLL-LLLKHP 317 NP D I L+K E + + F + +V T + AG ETTS L LL Sbjct: 209 NPADDIISDLLKAEVDGEM----FTDDEVVRTTMLILGAGVETTSHLLANSFYSLLYDDK 264 Query: 318 EVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYS-DLVPTGVPHAVTTDTKF 376 EV ++ E +D V V E+ RY +L+ + V D Sbjct: 265 EVYQELHENLDLV------------------PQAVEEMLRYRFNLI--KLDRTVKEDNDL 304 Query: 377 RNYLIPKGTTIMALLTSVLHDDKEFPNP---NIFDPGHFLDKNGNFKKSDYFMPFSAGKR 433 + +G ++ +++ D++ F + NI P N KK + F G Sbjct: 305 LGVELKEGENVVVWMSAANLDEEMFEDAFTLNIHRP--------NNKKH---LTFGNGPH 353 Query: 434 ICAGEGLARMELFLFLTTILQNF-NLKSVDDLK---NLNTTAVTKGIVSLP 480 C G LAR+E + LTT L+ F ++++V + NL +A + + SLP Sbjct: 354 FCLGAPLARLEAKIALTTFLKKFKHIEAVPSFQLEDNLTDSATGQTLTSLP 404 >3OO3-A nrPDB Length = 384 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 38/177 (21%), Positives = 66/177 (37%), Gaps = 32/177 (18%) Query: 280 SEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCM 339 +E + E L G + E + L +LLL+ HP+ A ++E+ + + Sbjct: 209 AEISDEELAGLAEGNLIMAAEQMAAQLAVAVLLLVTHPDQMALLREKPELI--------- 259 Query: 340 QDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDK 399 D+ E+ R++ +V P D + I G L S+L ++ Sbjct: 260 ---------DSATEEVLRHASIVEAPAPRVALADVRMAGRDIHAGDV---LTCSMLATNR 307 Query: 400 EFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF 456 PG D ++ M F G C G LAR++L + L ++ F Sbjct: 308 A--------PGDRFDIT---REKATHMAFGHGIHHCIGAPLARLQLRVALPAVVGRF 353 >4Z5P-A nrPDB Length = 400 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 55/251 (21%), Positives = 98/251 (39%), Gaps = 42/251 (16%) Query: 238 ALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVA 297 A R+Y+ + V +A+ P D + L+ + D + L+ L VA Sbjct: 187 ASIRAYLADLVSARRAA-----PHDDLLGVLVSARDDDDR----LTEDELITFGVTLLVA 237 Query: 298 GTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQR 357 G ET++ L + LL H + + ++E+ P + R+ V E+ R Sbjct: 238 GHETSAHQLGNMVYALLTHEDQLSLLREQ----------PELLPRA--------VEELLR 279 Query: 358 YSDLVPTGVPHA--VTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDK 415 + L GV +A D + + G ++A + D + F +P+ D Sbjct: 280 FVPL-GNGVGNARIALEDVELSGGTVRAGEGVVAAAVNANRDPRAFDDPDRLD------- 331 Query: 416 NGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF---NLKSVDDLKNLNTTAV 472 ++ + + F G C G LARMEL + + +L+ F L D T + Sbjct: 332 --ITREKNPHLAFGHGAHYCLGAQLARMELRVAIGGLLERFPGLRLAVPADQVEWKTGGL 389 Query: 473 TKGIVSLPPSY 483 +G LP ++ Sbjct: 390 FRGPQRLPIAW 400 >3RWL-A nrPDB Length = 426 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 44/176 (25%), Positives = 71/176 (40%), Gaps = 33/176 (18%) Query: 285 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSH 344 E +G V L V G +TT ++ G+L L K+P+ AK++ +P + Sbjct: 253 EEYLGNVLLLIVGGNDTTRNSMTGGVLALHKNPDQFAKLKA----------NPAL----- 297 Query: 345 MPYTDAVVHEIQRYSDLVPTGVPHAVTT---DTKFRNYLIPKGTTIMALLTSVLHDDKEF 401 + +V EI R+ T + H T D++ I KG ++ S DD+ Sbjct: 298 ---VETMVPEIIRWQ----TPLAHMRRTAIADSELGGKTIRKGDKVVMWYYSGNRDDEVI 350 Query: 402 PNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFN 457 P F +D+ + + F G C G LA M+L + IL F+ Sbjct: 351 DRPEEF----IIDR----PRPRQHLSFGFGIHRCVGNRLAEMQLRILWEEILTRFS 398 >3WVS-A nrPDB Length = 401 Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust. Identities = 51/230 (22%), Positives = 89/230 (38%), Gaps = 40/230 (17%) Query: 259 NPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPE 318 P D + +I+ +D + +++ +G L +AG ETT++ + + LL P+ Sbjct: 207 QPADDLISGMIEARDVQDKLTEQELLDHCIG----LLIAGHETTASQIPSFVYALLDQPQ 262 Query: 319 VTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTG----VPHAVTTDT 374 H + D +P + V E+ R+ VP G P D Sbjct: 263 ---------------HWKRLLDDPELIP---SAVEELFRF---VPLGSGSAAPRYAREDI 301 Query: 375 KFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRI 434 + L+ G ++ L + D F +P LD+ N + + F G Sbjct: 302 EVGGTLVRAGEPVLVALGAANRDGLRFEDPEEIK----LDRPSN-----HHIGFGHGIHH 352 Query: 435 CAGEGLARMELFLFLTTILQNF-NLKSVDDLKNLNTTAVTKGIVSLPPSY 483 C G LAR+EL L +L+ LK D+ + + +G S+P + Sbjct: 353 CLGAPLARLELQEALRALLERLPTLKVAGDIA-WKSEMMVRGPRSMPVGW 401 >5LIE-A nrPDB Length = 414 Score = 38.1 bits (87), Expect = 0.008, Method: Compositional matrix adjust. Identities = 40/164 (24%), Positives = 62/164 (37%), Gaps = 28/164 (17%) Query: 294 LFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVH 353 LF AG ETT ++ GLL L ++P+ + RS + Sbjct: 250 LFSAGAETTRNSIAGGLLALAENPDQLQTL------------------RSDFELLPTAIE 291 Query: 354 EIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFL 413 EI R++ P+ T R + G I A V+ + +P++FD Sbjct: 292 EIVRWTSPSPS------KRRTASRAVSL-GGQPIEAGQKVVVWEGSANRDPSVFDRADEF 344 Query: 414 DKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFN 457 D +K + + F G C G LAR+EL + +L F Sbjct: 345 DIT---RKPNPHLGFGQGVHYCLGANLARLELRVLFEELLSRFG 385 >2IAG-A nrPDB Length = 482 Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust. Identities = 39/172 (22%), Positives = 71/172 (41%), Gaps = 26/172 (15%) Query: 315 KHPEVTAKVQEEIDHVIGRHRSPCMQDRS-------HMPYTDAVVHEIQRYSDLVPTGVP 367 K+PE A V+ E++ ++ + P Q + P D+V+ E R + + Sbjct: 279 KNPEALAAVRGELESILWQAEQPVSQTTTLPQKVLDSTPVLDSVLSESLRLT--AAPFIT 336 Query: 368 HAVTTDTKF-----RNYLIPKGTTIMAL-LTSVLHDDKEFPNPNIFDPGHFLDKNGNFKK 421 V D R + + +G ++ S D + + +P +F FL+ +G+ KK Sbjct: 337 REVVVDLAMPMADGREFNLRRGDRLLLFPFLSPQRDPEIYTDPEVFKYNRFLNPDGSEKK 396 Query: 422 S---------DYFMPFSAGKRICAGEGLA--RMELFLFLTTILQNFNLKSVD 462 +Y MP+ AG C G A ++ F+FL + + L + D Sbjct: 397 DFYKDGKRLKNYNMPWGAGHNHCLGRSYAVNSIKQFVFLVLVHLDLELINAD 448 >5HDI-A nrPDB Length = 404 Score = 37.7 bits (86), Expect = 0.011, Method: Compositional matrix adjust. Identities = 41/191 (21%), Positives = 69/191 (36%), Gaps = 27/191 (14%) Query: 294 LFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVH 353 LF AG E+T+ L + +L P++ +V R++ A + Sbjct: 241 LFAAGGESTAALLGSAVWILATRPDIQQQV------------------RANPELLGAFIE 282 Query: 354 EIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFL 413 E RY H V T +P + ++ L + D +F P F L Sbjct: 283 ETLRYEPPFRGHYRH-VRNATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFR----L 337 Query: 414 DKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVT 473 D+ G + F G C G LAR+E + L +L ++ D+ + + Sbjct: 338 DRAGGKGH----ISFGKGAHFCVGAALARLEARIVLRLLLDRTSVIEAADVGGWLPSILV 393 Query: 474 KGIVSLPPSYQ 484 + I L + Q Sbjct: 394 RRIERLELAVQ 404 >5L94-A nrPDB Length = 410 Score = 37.7 bits (86), Expect = 0.011, Method: Compositional matrix adjust. Identities = 44/204 (21%), Positives = 77/204 (37%), Gaps = 46/204 (22%) Query: 260 PRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEV 319 P D I L++ ++E + E +VG L +AG ETT+ + + L++ Sbjct: 209 PGDDIISVLLQAKEEG----KQLTDEEIVGFSILLLIAGNETTTNLISNTIYCLMEDKAS 264 Query: 320 TAKVQEE-------IDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTT 372 +++ E I+ V+ R+RSP +H I V Sbjct: 265 FERLKREKELLPSGIEEVL-RYRSPVQ-----------ALHRI--------------VKE 298 Query: 373 DTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGK 432 D + G ++ + S D + F +P +F +D+ N M F G Sbjct: 299 DVTLAGKKLKAGEHVVPWMGSAHRDAEYFEDPEVFK----IDRKPNV-----HMAFGRGI 349 Query: 433 RICAGEGLARMELFLFLTTILQNF 456 C G LAR+E + L ++ + Sbjct: 350 HFCLGAPLARIEAKIMLAELIDRY 373 >6G71-A nrPDB Length = 405 Score = 37.7 bits (86), Expect = 0.013, Method: Compositional matrix adjust. Identities = 26/97 (26%), Positives = 41/97 (42%), Gaps = 12/97 (12%) Query: 350 AVVHEIQRYSDLVPTG-VPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFD 408 AV E R+ + P G VP DT+ Y IP+G + + S D + +P+ FD Sbjct: 271 AVFEESIRW--VAPIGMVPRQTVVDTELDGYFIPRGAKLGLCILSANRDRSVWSDPDRFD 328 Query: 409 PGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMEL 445 + S+ + F G +C G AR ++ Sbjct: 329 ---------IERGSEAHLAFGKGVHVCLGAWAARSQV 356 >5M0P-A nrPDB Length = 428 Score = 37.4 bits (85), Expect = 0.014, Method: Compositional matrix adjust. Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 1/77 (1%) Query: 342 RSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEF 401 +S Y E++RY VP +P D F+ IP G + + HD+ + Sbjct: 278 KSEPDYAYKFAQEVRRYYPFVPF-LPGKAKVDIDFQGVTIPAGVGLALDVYGTTHDESLW 336 Query: 402 PNPNIFDPGHFLDKNGN 418 +PN F P F +G+ Sbjct: 337 DDPNEFRPERFETWDGS 353 >1UE8-A nrPDB Length = 367 Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust. Identities = 44/190 (23%), Positives = 79/190 (41%), Gaps = 18/190 (9%) Query: 272 EQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVI 331 ++E D++K + I +L G +A+ ++ E Y +LL++ E T + I + I Sbjct: 172 KKELDSRKGK-EIVDLTGKIANSNLSELEKEG----YFILLMIAGNETTTNL---IGNAI 223 Query: 332 GRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALL 391 D V E R+S V + K R+ +I +G + + Sbjct: 224 EDFTLYNSWDYVREKGALKAVEEALRFSPPVMRTI-RVTKEKVKIRDQVIDEGELVRVWI 282 Query: 392 TSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTT 451 S D++ F +P+ F P D+ N + F +G +C G LAR+E + L Sbjct: 283 ASANRDEEVFKDPDSFIP----DRTPN-----PHLSFGSGIHLCLGAPLARLEARIALEE 333 Query: 452 ILQNFNLKSV 461 + F +K + Sbjct: 334 FAKKFRVKEI 343 >1GWI-A nrPDB Length = 411 Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust. Identities = 46/198 (23%), Positives = 73/198 (36%), Gaps = 31/198 (15%) Query: 260 PRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEV 319 P D + LI+ + D+ +V T+ + AG ETT + + ++ L HPE Sbjct: 209 PGDDLTSALIQASENGDH----LTDAEIVSTLQLMVAAGHETTISLIVNAVVNLSTHPEQ 264 Query: 320 TAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNY 379 A V S AVV E R+S + D + Sbjct: 265 RALVL------------------SGEAEWSAVVEETLRFSTPTSHVLIRFAAEDVPVGDR 306 Query: 380 LIPKGTTIMALLTSVLHDDKEF-PNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGE 438 +IP G ++ ++ D++ P + FD +GN S F G +C G Sbjct: 307 VIPAGDALIVSYGALGRDERAHGPTADRFD---LTRTSGNRHIS-----FGHGPHVCPGA 358 Query: 439 GLARMELFLFLTTILQNF 456 L+RME + L + F Sbjct: 359 ALSRMEAGVALPALYARF 376 >4JBT-A nrPDB Length = 410 Score = 37.0 bits (84), Expect = 0.020, Method: Compositional matrix adjust. Identities = 50/228 (21%), Positives = 85/228 (37%), Gaps = 36/228 (15%) Query: 230 HNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVG 289 ++ L+ + Y E V+ A P D + LI + ++ E ++G Sbjct: 186 QDERLRVIDEMHGYFTEMVRRKTA-----EPGDDLTSALIY----ATDGETPLTEEEVIG 236 Query: 290 TVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTD 349 + L AG ETT + + + LL HPE V+ D IG + R P Sbjct: 237 NLQALVAAGHETTVSLILTAVRALLSHPEQLRLVR---DGEIGWETAIEETLRWDGP--- 290 Query: 350 AVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHD-DKEFPNPNIFD 408 V+H + R++ T D + +IP+G ++ ++ D + + FD Sbjct: 291 -VIHLLMRFA-----------TEDIDLGDAVIPRGEGVVMSYRAIGRDITVHGADADDFD 338 Query: 409 PGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF 456 + + F G IC G LAR+E + L + F Sbjct: 339 I--------TRATAARHISFGHGPHICPGAALARLEAAIALPALFTRF 378 >4Z5Q-A nrPDB Length = 423 Score = 37.0 bits (84), Expect = 0.020, Method: Compositional matrix adjust. Identities = 49/229 (21%), Positives = 87/229 (37%), Gaps = 37/229 (16%) Query: 229 THNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLV 288 T + +++ + Y + VKE +A PRD + LI+ D L+ Sbjct: 204 TDEECVQSFMDLQKYFEDLVKERRA-----EPRDDLTSALIEARDAHDRLAEP----ELI 254 Query: 289 GTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYT 348 G + + G ETT++ + + +L + E+ ++ C D +P Sbjct: 255 GLCISILIGGFETTASEISSFVHVLQQRRELWTRL--------------CA-DPEAIP-- 297 Query: 349 DAVVHEIQRYSDLVPTGV-PHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIF 407 A V E+ R+ G+ P D L+ +G ++ ++V D F N + Sbjct: 298 -AAVEELLRFVPFAANGISPRYALEDMTVGGVLVREGEPVIVDTSAVNRDGLVFDNADEV 356 Query: 408 DPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF 456 +D+ N M F G C G LAR+EL L +++ Sbjct: 357 ----VIDRADN-----RHMVFGHGAHHCLGAHLARVELQEALKALVEGM 396 >4DO1-A nrPDB Length = 410 Score = 36.2 bits (82), Expect = 0.031, Method: Compositional matrix adjust. Identities = 22/111 (19%), Positives = 49/111 (44%), Gaps = 9/111 (8%) Query: 370 VTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFS 429 T + + +I +G ++ L S D + + +P+++D +K+ + F Sbjct: 303 TTREVELGGAVIGEGEKVLMFLGSANRDPRRWSDPDLYD---------ITRKTSGHVGFG 353 Query: 430 AGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLP 480 +G +C G+ +AR+E + L+ + + +D +G+ SLP Sbjct: 354 SGVHMCVGQLVARLEGEVMLSALARKVAAIDIDGPVKRRFNNTLRGLESLP 404 >6HQD-A nrPDB Length = 420 Score = 35.0 bits (79), Expect = 0.074, Method: Compositional matrix adjust. Identities = 36/175 (20%), Positives = 70/175 (40%), Gaps = 33/175 (18%) Query: 286 NLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHM 345 + +GT+A L V G +TT +++ + +P+ KV R++ Sbjct: 248 DFLGTLALLIVGGNDTTRSSMSGSAMACHLYPQEFDKV------------------RNNR 289 Query: 346 PYTDAVVHEIQRYSDLVPTGVPHAVTT---DTKFRNYLIPKGTTIMALLTSVLHDDKEFP 402 +V+ E+ R+ T + H T D +FR I KG ++ S DD+ Sbjct: 290 ALLASVIPEVVRWQ----TPIAHMRRTALEDVEFRGKQIRKGDKVVMWYLSGNRDDEVID 345 Query: 403 NPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFN 457 P +D + ++ + + F G C G LA ++L + + + ++ Sbjct: 346 RP--------MDFIADRPRARHHLSFGFGIHRCLGNRLAELQLKILWEEMCERYS 392 >5HIW-A nrPDB Length = 398 Score = 35.0 bits (79), Expect = 0.074, Method: Compositional matrix adjust. Identities = 43/199 (21%), Positives = 73/199 (36%), Gaps = 28/199 (14%) Query: 283 NIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDR 342 +E G V L + ETTS L L+ LL HP+ +++ Q Sbjct: 214 GVEACEGVVLTLILGSYETTSWMLANLLVALLAHPDAMNQLR---------------QQP 258 Query: 343 SHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFP 402 S +P + E R+ G+ V + + GT + L + +D++ +P Sbjct: 259 SLLPQA---IEESTRWCSSA-AGIVRFVEREATIGGETLAAGTILYLSLIARHYDEEIYP 314 Query: 403 NPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVD 462 P FD ++ + F G C G LARME + ++ +L+ F D Sbjct: 315 RPETFD---------IHRRPVGMLNFGGGLHYCVGAPLARMEARVGVSLLLERFPALRAD 365 Query: 463 DLKNLNTTAVTKGIVSLPP 481 + +G + P Sbjct: 366 PTVQPTFSTAPRGAAAFGP 384 >5DQN-A nrPDB Length = 426 Score = 34.7 bits (78), Expect = 0.085, Method: Compositional matrix adjust. Identities = 39/169 (23%), Positives = 66/169 (39%), Gaps = 30/169 (17%) Query: 294 LFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVH 353 L VAG ETT ++ +G++ ++P+ ++E P T A Sbjct: 248 LAVAGNETTRNSITHGMIAFAQNPDQWELYKKE------------------RPETAA--D 287 Query: 354 EIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFL 413 EI R++ V + D + I KG ++ S D++ F +P+ F+ Sbjct: 288 EIVRWATPV-SAFQRTALEDVELGGVQIKKGQRVVMSYRSANFDEEVFEDPHTFNILRSP 346 Query: 414 DKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF-NLKSV 461 + + F + G C G LARM + L I N +LK + Sbjct: 347 NPHVGFGGT--------GAHYCIGANLARMTINLIFNAIADNMPDLKPI 387 >3IVY-A nrPDB Length = 433 Score = 34.7 bits (78), Expect = 0.086, Method: Compositional matrix adjust. Identities = 50/222 (22%), Positives = 80/222 (36%), Gaps = 42/222 (18%) Query: 253 ASLDVNNPRDFIDCFLIKMEQEKDN-QKSEFNIENLVGTVADLFVAGTETTSTTLRYGLL 311 A NP D I LI+ + + + EF V L VAG ETT ++ G++ Sbjct: 228 AEEKAKNPADDIVTQLIQADIDGEKLSDDEFGF-----FVVMLAVAGNETTRNSITQGMM 282 Query: 312 LLLKHP---EVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPH 368 +HP E+ KV+ E EI R++ V T Sbjct: 283 AFAEHPDQWELYKKVRPE-----------------------TAADEIVRWATPV-TAFQR 318 Query: 369 AVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPF 428 D + I KG ++ S D++ F +P F+ + + F + Sbjct: 319 TALRDYELSGVQIKKGQRVVMFYRSANFDEEVFQDPFTFNILRNPNPHVGFGGT------ 372 Query: 429 SAGKRICAGEGLARMELFLFLTTILQNF-NLKSVDDLKNLNT 469 G C G LARM + L + + +LK + + L + Sbjct: 373 --GAHYCIGANLARMTINLIFNAVADHMPDLKPISAPERLRS 412 >2QBO-A nrPDB Length = 421 Score = 34.7 bits (78), Expect = 0.10, Method: Compositional matrix adjust. Identities = 46/193 (23%), Positives = 76/193 (39%), Gaps = 40/193 (20%) Query: 294 LFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVH 353 L V G +T L + + L K PE HR ++ +P A Sbjct: 246 LLVVGLDTVVNFLSFSMEFLAKSPE---------------HRQELIERPERIP---AACE 287 Query: 354 EIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLH--DDKEFPNPNIFDPGH 411 E+ R LV G +T+D +F + KG I LL +L D++E P D Sbjct: 288 ELLRRFSLVADG--RILTSDYEFHGVQLKKGDQI--LLPQMLSGLDERENACPMHVD--- 340 Query: 412 FLDKNGNFKKSDY-FMPFSAGKRICAGEGLARMELFLFLT---TILQNFNLKSVDDLKNL 467 F + F G +C G+ LAR E+ + L T + +F++ ++ Sbjct: 341 -------FSRQKVSHTTFGHGSHLCLGQHLARREIIVTLKEWLTRIPDFSIAPGAQIQ-- 391 Query: 468 NTTAVTKGIVSLP 480 + + + G+ +LP Sbjct: 392 HKSGIVSGVQALP 404 >5KYO-A nrPDB Length = 430 Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust. Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 9/80 (11%) Query: 370 VTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFS 429 V D +F L+ G +MA V DD +P F G +K+ F Sbjct: 323 VLRDQEFEGVLLKAGDMVMAPTVVVAMDDARNEDPLEFRLG---------RKARQHSTFG 373 Query: 430 AGKRICAGEGLARMELFLFL 449 G C G LARME+ + L Sbjct: 374 KGSHTCPGAHLARMEMKVVL 393 >1F4U-A nrPDB Length = 368 Score = 34.3 bits (77), Expect = 0.14, Method: Compositional matrix adjust. Identities = 47/169 (27%), Positives = 66/169 (39%), Gaps = 24/169 (14%) Query: 287 LVGTVADLFVAGTETTSTT----------LRYGLLLLLKHPEVTAKVQEEIDHVIGRHRS 336 L+G V D +GTE S L Y +LLL+ E T + + VI R Sbjct: 171 LIGYVKDHLNSGTEVVSRVVNSNLSDIEKLGYIILLLIAGNETTTNLIS--NSVIDFTRF 228 Query: 337 PCMQD-RSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVL 395 Q R Y A+ E RYS V V K + I +G + + S Sbjct: 229 NLWQRIREENLYLKAI-EEALRYSPPVMRTV-RKTKERVKLGDQTIEEGEYVRVWIASAN 286 Query: 396 HDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARME 444 D++ F + F P D+N N + F +G +C G LAR+E Sbjct: 287 RDEEVFHDGEKFIP----DRNPN-----PHLSFGSGIHLCLGAPLARLE 326 >3NV6-A nrPDB Length = 452 Score = 33.1 bits (74), Expect = 0.29, Method: Compositional matrix adjust. Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 13/87 (14%) Query: 370 VTTDTKFRNYLIPKGTTIMALLTSVLH--DDKEFPNPNIFDPGHFLDKNGNFKKSDYFMP 427 V D +++ + +G M LL + LH DD P P D ++S Sbjct: 343 VAKDQEYKGVFLKRGD--MILLPTALHGLDDAANPEPWKLDFS---------RRSISHST 391 Query: 428 FSAGKRICAGEGLARMELFLFLTTILQ 454 F G CAG LARME+ + L L+ Sbjct: 392 FGGGPHRCAGMHLARMEVIVTLEEWLK 418 >3B98-A nrPDB Length = 475 Score = 33.1 bits (74), Expect = 0.30, Method: Compositional matrix adjust. Identities = 41/166 (24%), Positives = 67/166 (40%), Gaps = 22/166 (13%) Query: 313 LLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTT 372 LL HPE V+EEI G+H + + + P D+V+ E R + + VT Sbjct: 280 LLTHPEALRAVREEIQG--GKHLR-LEERQKNTPVFDSVLWETLRLT--AAALITRDVTQ 334 Query: 373 DTKF-----RNYLIPKGTTIMAL-LTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYF- 425 D K + Y + +G + S D + P +F FL+ + KK D+F Sbjct: 335 DKKICLSNGQEYHLRRGDRLCVFPFISPQMDPQIHQQPEMFQFDRFLNADRTEKK-DFFK 393 Query: 426 ---------MPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVD 462 +P+ +C G A + + TIL F+++ D Sbjct: 394 NGARVKYPSVPWGTEDNLCPGRHFAVHAIKELVFTILTRFDVELCD 439 >2NZA-A nrPDB Length = 413 Score = 33.1 bits (74), Expect = 0.31, Method: Compositional matrix adjust. Identities = 39/179 (21%), Positives = 65/179 (36%), Gaps = 29/179 (16%) Query: 279 KSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPC 338 + E VG L + G E + + L LLL E+ A+++E P Sbjct: 227 RGEVGETEAVGLAGPLQIGG-EAVTHNVGQMLYLLLTRRELMARMRER----------PG 275 Query: 339 MQDRSHMPYTDAVVHEIQRY-SDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHD 397 + + E+ R+ S G+ D + I G + + D Sbjct: 276 ARG--------TALDELLRWISHRTSVGLARIALEDVEVHGTRIAAGEPVYVSYLAANRD 327 Query: 398 DKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF 456 FP+P+ D LD++ N + + G C G LARM+ L + T+L+ Sbjct: 328 PDVFPDPDRID----LDRDPN-----PHLAYGNGHHFCTGAVLARMQTELLVDTLLERL 377 >5DE9-A nrPDB Length = 410 Score = 32.7 bits (73), Expect = 0.37, Method: Compositional matrix adjust. Identities = 43/213 (20%), Positives = 81/213 (38%), Gaps = 40/213 (18%) Query: 279 KSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPC 338 + E + VG L + G T+ + + LLL PE+ +++ E P Sbjct: 224 RDEITLSEAVGLAVLLQIGGEAVTNNSGQM-FHLLLSRPELAERLRSE----------PE 272 Query: 339 MQDRSHMPYTDAVVHEIQRYSDLVP----TGVPHAVTTDTKFRNYLIPKGTTIMALLTSV 394 ++ R+ + E+ R+ +P G+ D + + I G + + Sbjct: 273 IRPRA--------IDELLRW---IPHRNAVGLSRIALEDVEIKGVRIRAGDAVYVSYLAA 321 Query: 395 LHDDKEFPNPNIFDPGHFLDKNGNFKKS-DYFMPFSAGKRICAGEGLARMELFLFLTTIL 453 D + FP+P+ D F++S + + F G C G LAR+E L + +L Sbjct: 322 NRDPEVFPDPDRID----------FERSPNPHVSFGFGPHYCPGGMLARLESELLVDAVL 371 Query: 454 Q---NFNLKSVDDLKNLNTTAVTKGIVSLPPSY 483 L + A+ +G +LP ++ Sbjct: 372 DRVPGLKLAVAPEDVPFKKGALIRGPEALPVTW 404 >3AWQ-A nrPDB Length = 415 Score = 32.3 bits (72), Expect = 0.47, Method: Compositional matrix adjust. Identities = 29/122 (23%), Positives = 49/122 (40%), Gaps = 10/122 (8%) Query: 347 YTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNI 406 Y + V E++R+ P V A + D ++ P+G ++ L HD + +P Sbjct: 273 YAELFVQEVRRFYPFFPAVVARA-SQDFEWEGMAFPEGRQVVLDLYGSNHDAATWADPQE 331 Query: 407 FDPGHFLDKNGNFKKSDYFMPFSAGKRI----CAGEG--LARMELFLFLTTILQNFNLKS 460 F P F + + S F+P G C GE LA M++ L +++ Sbjct: 332 FRPERFRAWD---EDSFNFIPQGGGDHYLGHRCPGEWIVLAIMKVAAHLLVNAMRYDVPD 388 Query: 461 VD 462 D Sbjct: 389 QD 390 >2ZQJ-A nrPDB Length = 417 Score = 32.3 bits (72), Expect = 0.51, Method: Compositional matrix adjust. Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 8/93 (8%) Query: 352 VHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGH 411 V E++RY P + V D + N KGT+++ L HD + + +P+ F P Sbjct: 280 VQEVRRYYPFGPF-LGALVKKDFVWNNCEFKKGTSVLLDLYGTNHDPRLWDHPDEFRPER 338 Query: 412 FLDKNGNFKKSDYFMPFSAGK----RICAGEGL 440 F ++ N +P G C GEG+ Sbjct: 339 FAEREENLFD---MIPQGGGHAEKGHRCPGEGI 368 >4C9K-A nrPDB Length = 421 Score = 32.0 bits (71), Expect = 0.58, Method: Compositional matrix adjust. Identities = 43/190 (22%), Positives = 75/190 (39%), Gaps = 38/190 (20%) Query: 300 ETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYS 359 +T L + ++ L +HPE A+++ R P R V E+ R Sbjct: 259 DTVVNFLGFMMIYLSRHPETVAEMR----------REPLKLQRG--------VEELFRRF 300 Query: 360 DLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLH--DDKEFPNPNIFDPGHFLDKNG 417 +V V +D +F ++ +G I LL + LH DD+ +P D Sbjct: 301 AVVSDA--RYVVSDMEFHGTMLKEGDLI--LLPTALHGLDDRHHDDPMTVDLS------- 349 Query: 418 NFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQ---NFNLKSVDDLKNLNTTAVTK 474 ++ F+ G CAG LAR+E+ + L L F LK D + + + Sbjct: 350 --RRDVTHSTFAQGPHRCAGMHLARLEVTVMLQEWLARIPEFRLK--DRAVPIYHSGIVA 405 Query: 475 GIVSLPPSYQ 484 + ++P ++ Sbjct: 406 AVENIPLEWE 415 >2FR7-A nrPDB Length = 412 Score = 31.6 bits (70), Expect = 0.80, Method: Compositional matrix adjust. Identities = 22/110 (20%), Positives = 45/110 (40%), Gaps = 9/110 (8%) Query: 371 TTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSA 430 T D + I +G ++ L S D + + +P+ +D +K+ + F + Sbjct: 306 TRDVELAGATIGEGEKVLMFLGSANRDPRRWDDPDRYD---------ITRKTSGHVGFGS 356 Query: 431 GKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLP 480 G +C G+ +AR+E + L + + + +G+ SLP Sbjct: 357 GVHMCVGQLVARLEGEVVLAALARKVAAIEIAGPLKRRFNNTLRGLESLP 406 >4XE3-A nrPDB Length = 407 Score = 31.6 bits (70), Expect = 0.92, Method: Compositional matrix adjust. Identities = 27/108 (25%), Positives = 45/108 (41%), Gaps = 10/108 (9%) Query: 350 AVVHEIQRYSDLVPTG-VPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFD 408 A V E+ RY+ LV G T D + + G + S D++ +FD Sbjct: 279 AAVEEMLRYTPLVSAGSFVRVATEDVELSTVTVRAGEPCVVHFASANRDEE------VFD 332 Query: 409 PGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF 456 LD + ++ + + F G C G L R+EL L+ +++ F Sbjct: 333 HADELDFH---RERNPHIAFGHGAHHCIGAQLGRLELQEALSALVRRF 377 >1ODO-A nrPDB Length = 408 Score = 31.2 bits (69), Expect = 1.0, Method: Compositional matrix adjust. Identities = 51/215 (23%), Positives = 84/215 (39%), Gaps = 38/215 (17%) Query: 259 NPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPE 318 P D + LI ++ + + E L T+ + AG ETT + + LL P+ Sbjct: 205 TPGDDMTSLLIAA-RDDEGDGDRLSPEELRDTLLLMISAGYETTVNVIDQAVHTLLTRPD 263 Query: 319 VTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVP--HAVTTDTKF 376 A V+ + + + D VV E R+ V +P +AVT Sbjct: 264 QLALVR-----------------KGEVTWAD-VVEETLRHEPAV-KHLPLRYAVT----- 299 Query: 377 RNYLIPKGTTIM---ALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKR 433 + +P G TI +L S ++ +P+ + D K+ + F G Sbjct: 300 -DIALPDGRTIARGEPILASYAAANR---HPDWHEDADTFDATRTVKE---HLAFGHGVH 352 Query: 434 ICAGEGLARMELFLFLTTILQNF-NLKSVDDLKNL 467 C G LARME+ L L ++ F +L+ D + L Sbjct: 353 FCLGAPLARMEVTLALESLFGRFPDLRLADPAEEL 387 >3OFT-A nrPDB Length = 396 Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust. Identities = 44/169 (26%), Positives = 59/169 (34%), Gaps = 37/169 (21%) Query: 293 DLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVV 352 +L G +T + + L L +HPE ++E D + P D Sbjct: 230 NLLFGGLDTVAAMIGMVALHLARHPEDQRLLRERPDLI------PAAAD----------- 272 Query: 353 HEIQRYSDLVPT-GVPHAVTTDTKFRNYLIPKGTTIMALLTSVLH--DDKEFPNPN--IF 407 ++RY PT V D I KG + L SVLH D F P F Sbjct: 273 ELMRRY----PTVAVSRNAVADVDADGVTIRKGDLV--YLPSVLHNLDPASFEAPEEVRF 326 Query: 408 DPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF 456 D G ++ G C G GLARME+ +FL L Sbjct: 327 DRGLAPIRHTTM---------GVGAHRCVGAGLARMEVIVFLREWLGGM 366 >1PIO-A nrPDB Length = 257 Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust. Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 7/100 (7%) Query: 100 SPISQRIT-------KGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCL 152 SP S++ T K L + +NGK KE ++F L + N G I+D V ++ Sbjct: 141 SPKSKKDTSTPAAFGKTLNKLIANGKLSKENKKFLLDLMLNNKSGDTLIKDGVPKDYKVA 200 Query: 153 VEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQ 192 + + T AS D F+ I V+F + + D+ Sbjct: 201 DKSGQSTYASRNDVAFVYPKGQSEPIVLVIFTNKDNKSDK 240 >2UUQ-A nrPDB Length = 414 Score = 30.8 bits (68), Expect = 1.5, Method: Compositional matrix adjust. Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 9/103 (8%) Query: 351 VVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPG 410 V E+ R + V G+ T D + IP G ++ L S D++++ P+ + Sbjct: 286 AVEELLRLTSPV-QGLARTTTRDVTIGDTTIPAGRRVLLLYGSANRDERQY-GPDAAE-- 341 Query: 411 HFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTIL 453 LD + + FS G C G ARM+ + LT +L Sbjct: 342 --LDVT---RCPRNILTFSHGAHHCLGAAAARMQCRVALTELL 379 >2JGU-A nrPDB Length = 775 Score = 30.8 bits (68), Expect = 1.5, Method: Compositional matrix adjust. Identities = 20/50 (40%), Positives = 28/50 (56%), Gaps = 6/50 (12%) Query: 244 IREKVKEHQASLDVNN------PRDFIDCFLIKMEQEKDNQKSEFNIENL 287 +REKV+EH A +D+ R ID LI ME E++ + F+IE L Sbjct: 96 LREKVREHPAVVDIFEYDIPFAKRYLIDKGLIPMEGEEELKILAFDIETL 145 >2VWK-A nrPDB Length = 773 Score = 30.4 bits (67), Expect = 1.7, Method: Compositional matrix adjust. Identities = 19/50 (38%), Positives = 28/50 (56%), Gaps = 6/50 (12%) Query: 244 IREKVKEHQASLDVNN------PRDFIDCFLIKMEQEKDNQKSEFNIENL 287 IR+K+KEH A +D+ R ID LI ME +++ + F+IE L Sbjct: 96 IRDKIKEHPAVVDIYEYDIPFAKRYLIDKGLIPMEGDEELKMLAFDIETL 145 >4DJD-D nrPDB Length = 323 Score = 30.4 bits (67), Expect = 2.0, Method: Compositional matrix adjust. Identities = 13/32 (40%), Positives = 22/32 (68%), Gaps = 1/32 (3%) Query: 301 TTSTTLRYGL-LLLLKHPEVTAKVQEEIDHVI 331 T + L+ G +LL++HPE A+V+E ID ++ Sbjct: 287 TATALLQAGAHILLMRHPEAVARVKENIDQLM 318 >3MCR-A nrPDB Length = 213 Score = 30.4 bits (67), Expect = 2.0, Method: Compositional matrix adjust. Identities = 15/49 (30%), Positives = 24/49 (48%) Query: 274 EKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAK 322 EKDN E + + +A + + G +TT T YG L + +H A+ Sbjct: 15 EKDNLPRELGTQRINSPIARMGMFGAKTTGDTSGYGRLRVYRHVPAAAQ 63 >6BLD-A nrPDB Length = 419 Score = 30.0 bits (66), Expect = 2.3, Method: Compositional matrix adjust. Identities = 29/115 (25%), Positives = 42/115 (36%), Gaps = 18/115 (15%) Query: 294 LFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVH 353 L VAG +TT T+ +GL L P A + + D IG V Sbjct: 257 LAVAGNDTTRQTISHGLKALTDFPSQKAWLLADFDTRIG-----------------TAVE 299 Query: 354 EIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFD 408 E+ R++ V T D + LI G ++ S D+ F +P D Sbjct: 300 ELVRWATPVMT-FRRTAAADFELGGQLIRAGEKVVMFYASGNWDEDAFCHPERLD 353 >2GU2-A nrPDB Length = 312 Score = 29.6 bits (65), Expect = 2.8, Method: Compositional matrix adjust. Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 20/75 (26%) Query: 223 IDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDV----NNPRD------FIDCFLIKME 272 I F GTH L V L +++ + H+A L+V NPR +IDC L ++ Sbjct: 13 IAIFGGTHGNELTGVFLVTHWLKNGAEVHRAGLEVKPFITNPRAVEKCTRYIDCDLNRV- 71 Query: 273 QEKDNQKSEFNIENL 287 F++ENL Sbjct: 72 ---------FDLENL 77 >2KU2-A nrPDB Length = 237 Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust. Identities = 17/37 (45%), Positives = 20/37 (54%) Query: 257 VNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVAD 293 V + R +D I +QEK S NIENLV VAD Sbjct: 86 VADARVLVDFARISAQQEKVTYGSLVNIENLVKRVAD 122 >5H12-A nrPDB Length = 775 Score = 29.3 bits (64), Expect = 3.8, Method: Compositional matrix adjust. Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 6/50 (12%) Query: 244 IREKVKEHQASLDVNN------PRDFIDCFLIKMEQEKDNQKSEFNIENL 287 IR+K++EH A +D+ R ID LI ME +++ + F+IE L Sbjct: 96 IRDKIREHSAVIDIFEYDIPFAKRYLIDKGLIPMEGDEELKLLAFDIETL 145 >1D5A-A nrPDB Length = 733 Score = 29.3 bits (64), Expect = 3.8, Method: Compositional matrix adjust. Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 6/50 (12%) Query: 244 IREKVKEHQASLDVNN------PRDFIDCFLIKMEQEKDNQKSEFNIENL 287 IR+K++EH A +D+ R ID LI ME +++ + F+IE L Sbjct: 96 IRDKIREHPAVVDIYEYDIPFAKRYLIDRGLIPMEGDEELRMLAFDIETL 145 >3T3N-A nrPDB Length = 562 Score = 28.9 bits (63), Expect = 4.9, Method: Compositional matrix adjust. Identities = 18/72 (25%), Positives = 40/72 (55%), Gaps = 4/72 (5%) Query: 98 GNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELR 157 G P+ + +++G + + + E+RR +L L+N K+ +E R++++ + V++ Sbjct: 490 GEDPVVEVVSRGF--VKAGERLLGEVRRMALEALKNGVREKKPLE-RIRDDIYYPVKKFL 546 Query: 158 KTKASPCDPTFI 169 K KA+ DP + Sbjct: 547 K-KATGRDPMIL 557 >3BUJ-A nrPDB Length = 397 Score = 28.5 bits (62), Expect = 6.2, Method: Compositional matrix adjust. Identities = 46/206 (22%), Positives = 80/206 (38%), Gaps = 34/206 (16%) Query: 286 NLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHM 345 +V TV G ET ++ + +L LL HP+ ++D + R P + ++ Sbjct: 222 EIVSTVVTFIFTGHETVASQVGNAVLSLLAHPD-------QLDLL---RRRPDLLAQA-- 269 Query: 346 PYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPN 405 V E RY V + + D + R + + ++ L + D + + P+ Sbjct: 270 ------VEECLRYDPSVQSNT-RQLDVDVELRGRRLRRDDVVVVLAGAANRDPRRYDRPD 322 Query: 406 IFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQ--NFNLKSVDD 463 FD ++++ M F AG R C G LAR +L + + + L D Sbjct: 323 DFD----IERDPVPS-----MSFGAGMRYCLGSYLARTQLRAAVAALARLPGLRLGCASD 373 Query: 464 LKNLNTTAVTKGIVSLPPSYQICFIP 489 + +G+ SLP I F P Sbjct: 374 ALAYQPRTMFRGLASLP----IAFTP 395 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2NNH-A nrPDB 671 0.0 5W0C-A nrPDB 611 e-175 4GQS-A nrPDB 609 e-175 1N6B-A nrPDB 594 e-170 3E6I-A nrPDB 550 e-157 4H1N-A nrPDB 545 e-155 2PG7-A nrPDB 524 e-149 3IBD-A nrPDB 523 e-149 5E0E-A nrPDB 523 e-149 5E58-A nrPDB 523 e-149 6B82-A nrPDB 437 e-123 3TBG-A nrPDB 428 e-120 3DL9-A nrPDB 421 e-118 4R20-A nrPDB 414 e-116 6DWN-A nrPDB 411 e-115 2HI4-A nrPDB 389 e-108 4R1Z-A nrPDB 388 e-108 5UYS-A nrPDB 387 e-108 5VBU-A nrPDB 376 e-104 6IQ5-A nrPDB 357 7e-99 5YLW-A nrPDB 355 3e-98 3QZ1-A nrPDB 349 2e-96 6DA2-A nrPDB 346 1e-95 5VEU-A nrPDB 344 8e-95 3K9V-A nrPDB 277 9e-75 3MDV-A nrPDB 271 4e-73 2VE3-A nrPDB 258 4e-69 3SN5-A nrPDB 255 3e-68 3EL3-A nrPDB 246 2e-65 6AYB-A nrPDB 245 5e-65 2VZM-A nrPDB 231 4e-61 4MM0-A nrPDB 229 2e-60 5CJE-A nrPDB 229 2e-60 4OQS-A nrPDB 229 3e-60 4OQR-A nrPDB 226 1e-59 4UBS-A nrPDB 226 2e-59 5Y1I-A nrPDB 225 3e-59 3EJB-B nrPDB 225 3e-59 5JLC-A nrPDB 225 4e-59 2WX2-A nrPDB 223 1e-58 4WMZ-A nrPDB 223 1e-58 5FSA-A nrPDB 221 4e-58 5VWS-A nrPDB 221 4e-58 2Z36-A nrPDB 220 1e-57 6C94-A nrPDB 219 2e-57 2Y5N-A nrPDB 218 7e-57 3L4D-A nrPDB 216 1e-56 3JUS-A nrPDB 215 3e-56 3A50-A nrPDB 215 4e-56 6CR2-A nrPDB 214 8e-56 2ZBZ-A nrPDB 213 1e-55 4YZR-A nrPDB 212 3e-55 3R9C-A nrPDB 211 7e-55 5IT1-A nrPDB 210 1e-54 5EX6-C nrPDB 208 4e-54 4WPZ-A nrPDB 208 4e-54 2W0A-A nrPDB 208 6e-54 3N9Z-A nrPDB 207 1e-53 3ABA-A nrPDB 206 1e-53 5YSW-A nrPDB 206 2e-53 3ABB-A nrPDB 204 5e-53 5OFQ-A nrPDB 202 3e-52 4RM4-A nrPDB 201 4e-52 3MZS-A nrPDB 201 5e-52 1Z8P-A nrPDB 201 7e-52 6A7J-A nrPDB 198 7e-51 2X2N-A nrPDB 197 9e-51 6FSH-A nrPDB 196 1e-50 6GMF-A nrPDB 196 2e-50 3TYW-A nrPDB 195 3e-50 4TX3-A nrPDB 194 6e-50 5FOI-A nrPDB 194 8e-50 4KPA-A nrPDB 193 1e-49 2WM5-A nrPDB 192 3e-49 1UED-A nrPDB 192 4e-49 6F0B-A nrPDB 191 4e-49 2WIO-A nrPDB 191 5e-49 6GK6-A nrPDB 191 6e-49 6A7I-A nrPDB 190 1e-48 1EHE-A nrPDB 190 1e-48 5NWS-A nrPDB 189 2e-48 1LG9-A nrPDB 189 3e-48 6B11-A nrPDB 188 4e-48 5XW2-A nrPDB 187 1e-47 6M7L-A nrPDB 186 1e-47 1CPT-A nrPDB 186 2e-47 6CVC-A nrPDB 185 5e-47 5XJN-A nrPDB 184 5e-47 5GWE-A nrPDB 184 6e-47 5XNT-A nrPDB 182 2e-46 5L1U-A nrPDB 182 3e-46 4GGV-A nrPDB 182 4e-46 4YT3-A nrPDB 181 4e-46 3MGX-A nrPDB 181 8e-46 4TRI-A nrPDB 177 7e-45 5Z9I-A nrPDB 176 2e-44 2XKR-A nrPDB 176 2e-44 3P3Z-A nrPDB 174 7e-44 3S79-A nrPDB 172 4e-43 6M7X-A nrPDB 171 7e-43 4ZGX-A nrPDB 170 1e-42 3OO3-A nrPDB 168 6e-42 3A1L-A nrPDB 167 1e-41 3TKT-A nrPDB 165 3e-41 1Q5D-A nrPDB 157 1e-38 5FYF-A nrPDB 157 1e-38 2RFC-A nrPDB 156 2e-38 5LIV-A nrPDB 151 5e-37 6F88-A nrPDB 151 7e-37 6GII-A nrPDB 137 1e-32 2IJ7-A nrPDB 134 1e-31 1WIY-A nrPDB 131 6e-31 6FYJ-A nrPDB 109 3e-24 5YHJ-A nrPDB 101 6e-22 Sequences not found previously or not previously below threshold: 5L94-A nrPDB 210 1e-54 4Z5P-A nrPDB 209 2e-54 3WVS-A nrPDB 197 1e-50 5LIE-A nrPDB 186 2e-47 4XE3-A nrPDB 184 6e-47 4JBT-A nrPDB 183 1e-46 1ODO-A nrPDB 181 4e-46 1GWI-A nrPDB 181 8e-46 4Z5Q-A nrPDB 180 1e-45 3NC3-A nrPDB 169 3e-42 5DE9-A nrPDB 164 6e-41 6HQG-A nrPDB 164 7e-41 3RWL-A nrPDB 160 1e-39 6HQW-A nrPDB 152 2e-37 2FR7-A nrPDB 152 4e-37 5HH3-A nrPDB 151 9e-37 5DQN-A nrPDB 150 1e-36 2NZA-A nrPDB 149 2e-36 1F4U-A nrPDB 149 3e-36 4DO1-A nrPDB 149 3e-36 2X9P-A nrPDB 147 1e-35 1UE8-A nrPDB 147 1e-35 5H1Z-A nrPDB 146 2e-35 4PWV-A nrPDB 144 8e-35 6G5O-A nrPDB 143 1e-34 5HDI-A nrPDB 142 2e-34 2UUQ-A nrPDB 140 1e-33 3IVY-A nrPDB 140 1e-33 6HQD-A nrPDB 140 1e-33 5EX8-A nrPDB 139 2e-33 5HIW-A nrPDB 137 1e-32 3WEC-A nrPDB 137 1e-32 6BLD-A nrPDB 136 2e-32 6DCD-A nrPDB 133 2e-31 2WIY-A nrPDB 131 8e-31 5D3U-A nrPDB 130 1e-30 6G71-A nrPDB 128 7e-30 3BUJ-A nrPDB 124 6e-29 3OFT-A nrPDB 119 3e-27 3B98-A nrPDB 117 9e-27 5OMS-A nrPDB 117 1e-26 4FB2-A nrPDB 115 3e-26 2QBO-A nrPDB 114 1e-25 5KYO-A nrPDB 109 3e-24 2IAG-A nrPDB 108 7e-24 3NV6-A nrPDB 103 2e-22 2ZQJ-A nrPDB 100 1e-21 4C9K-A nrPDB 97 2e-20 5M0P-A nrPDB 94 2e-19 3AWQ-A nrPDB 90 2e-18 2RCM-A nrPDB 79 4e-15 3DBM-A nrPDB 67 2e-11 2YJN-B nrPDB 59 7e-09 4YXC-B nrPDB 34 0.24 3GFZ-A nrPDB 33 0.34 4YXB-D nrPDB 32 0.41 6FSZ-KK nrPDB 32 0.46 2HBL-A nrPDB 32 0.71 6HIW-DG nrPDB 32 0.79 4DJD-D nrPDB 31 1.00 1GSQ-A nrPDB 31 1.00 5L9W-B nrPDB 30 2.5 4TKV-B nrPDB 30 2.6 6IGZ-A nrPDB 29 3.5 3K7D-A nrPDB 29 3.9 1CLI-A nrPDB 29 5.7 1SCZ-A nrPDB 28 9.0 4HE8-H nrPDB 28 9.8 1O7A-A nrPDB 28 9.8 >2NNH-A nrPDB Length = 476 Score = 671 bits (1731), Expect = 0.0, Method: Composition-based stats. Identities = 463/472 (98%), Positives = 468/472 (99%) Query: 19 LWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFH 78 + +++ + KLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFH Sbjct: 1 MAKKTSSKGKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFH 60 Query: 79 GYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGK 138 GYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGK Sbjct: 61 GYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGK 120 Query: 139 RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM 198 RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM Sbjct: 121 RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM 180 Query: 199 KRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVN 258 KRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVN Sbjct: 181 KRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVN 240 Query: 259 NPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPE 318 NPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPE Sbjct: 241 NPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPE 300 Query: 319 VTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRN 378 VTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRN Sbjct: 301 VTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRN 360 Query: 379 YLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGE 438 YLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGE Sbjct: 361 YLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGE 420 Query: 439 GLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIPV 490 GLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIPV Sbjct: 421 GLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIPV 472 >5W0C-A nrPDB Length = 477 Score = 611 bits (1576), Expect = e-175, Method: Composition-based stats. Identities = 365/470 (77%), Positives = 408/470 (86%) Query: 21 RQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGY 80 + S R KLPPGPTPLP+IGN+LQI +KDI KS TN SKVYGPVFT+YFG+ PIVV HGY Sbjct: 4 KTSSGRGKLPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGY 63 Query: 81 EAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRS 140 EAVKEALID GEEFSGRG P+++R +G GI+ SNGK+WKEIRRFSL TLRNFGMGKRS Sbjct: 64 EAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRS 123 Query: 141 IEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKR 200 IEDRVQEEA CLVEELRKTKASPCDPTFILGCAPCNVICS++F KRFDYKDQ FL LM++ Sbjct: 124 IEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEK 183 Query: 201 FNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNP 260 NEN +IL+SPWIQ+CNNF +ID FPGTHNK+LKNVA +SYI EKVKEHQ S+D+NNP Sbjct: 184 LNENIKILSSPWIQICNNFSPIIDYFPGTHNKLLKNVAFMKSYILEKVKEHQESMDMNNP 243 Query: 261 RDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVT 320 +DFIDCFL+KME+EK NQ SEF IE+L T DLF AGTETTSTTLRY LLLLLKHPEVT Sbjct: 244 QDFIDCFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVT 303 Query: 321 AKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYL 380 AKVQEEI+ VIGR+RSPCMQDRSHMPYTDAVVHE+QRY DL+PT +PHAVT D KFRNYL Sbjct: 304 AKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYL 363 Query: 381 IPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGL 440 IPKGTTI+ LTSVLHD+KEFPNP +FDP HFLD+ GNFKKS YFMPFSAGKRIC GE L Sbjct: 364 IPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEAL 423 Query: 441 ARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIPV 490 A MELFLFLT+ILQNFNLKS+ D KNL+TT V G S+PP YQ+CFIP+ Sbjct: 424 AGMELFLFLTSILQNFNLKSLVDPKNLDTTPVVNGFASVPPFYQLCFIPI 473 >4GQS-A nrPDB Length = 477 Score = 609 bits (1571), Expect = e-175, Method: Composition-based stats. Identities = 364/470 (77%), Positives = 411/470 (87%) Query: 21 RQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGY 80 + S R KLPPGPTPLP+IGN+LQID+KD+ KS TN SK+YGPVFT+YFG+ +VV HGY Sbjct: 4 KTSSGRGKLPPGPTPLPVIGNILQIDIKDVSKSLTNLSKIYGPVFTLYFGLERMVVLHGY 63 Query: 81 EAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRS 140 E VKEALID GEEFSGRG+ P+++R +G GI+ SNGKRWKEIRRFSL TLRNFGMGKRS Sbjct: 64 EVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRS 123 Query: 141 IEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKR 200 IEDRVQEEA CLVEELRKTKASPCDPTFILGCAPCNVICS++FQKRFDYKDQ FL LM++ Sbjct: 124 IEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQFLNLMEK 183 Query: 201 FNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNP 260 NEN RI+++PWIQ+CNNFP +ID FPGTHNK+LKN+A S I EKVKEHQ S+D+NNP Sbjct: 184 LNENIRIVSTPWIQICNNFPTIIDYFPGTHNKLLKNLAFMESDILEKVKEHQESMDINNP 243 Query: 261 RDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVT 320 RDFIDCFLIKME+EK NQ+SEF IENLV T ADL AGTETTSTTLRY LLLLLKHPEVT Sbjct: 244 RDFIDCFLIKMEKEKQNQQSEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVT 303 Query: 321 AKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYL 380 AKVQEEI+ V+GR+RSPCMQDR HMPYTDAVVHE+QRY DL+PT +PHAVT D KFRNYL Sbjct: 304 AKVQEEIERVVGRNRSPCMQDRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYL 363 Query: 381 IPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGL 440 IPKGTTI+ LTSVLHD+KEFPNP +FDP HFLD+ GNFKKS+YFMPFSAGKRIC GEGL Sbjct: 364 IPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGL 423 Query: 441 ARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIPV 490 ARMELFLFLT ILQNFNLKS+ D K+L+TT V G S+PP YQ+CFIP+ Sbjct: 424 ARMELFLFLTFILQNFNLKSLIDPKDLDTTPVVNGFASVPPFYQLCFIPI 473 >1N6B-A nrPDB Length = 473 Score = 594 bits (1531), Expect = e-170, Method: Composition-based stats. Identities = 341/472 (72%), Positives = 395/472 (83%), Gaps = 3/472 (0%) Query: 19 LWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFH 78 + +++ + KLPPGPTP PIIGN+LQID KDI KS T FS+ YGPVFTVY GM P VV H Sbjct: 1 MAKKTSSKGKLPPGPTPFPIIGNILQIDAKDISKSLTKFSECYGPVFTVYLGMKPTVVLH 60 Query: 79 GYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGK 138 GYEAVKEAL+D GEEF+GRG+ PI ++++KGLGI SN K WKE+RRFSL TLRNFGMGK Sbjct: 61 GYEAVKEALVDLGEEFAGRGSVPILEKVSKGLGIAFSNAKTWKEMRRFSLMTLRNFGMGK 120 Query: 139 RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM 198 RSIEDR+QEEA CLVEELRKT ASPCDPTFILGCAPCNVICSV+F RFDYKD+ FL LM Sbjct: 121 RSIEDRIQEEARCLVEELRKTNASPCDPTFILGCAPCNVICSVIFHNRFDYKDEEFLKLM 180 Query: 199 KRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVN 258 + +EN +L +PW+QV NNFP L+D FPG H +LKN +++I EKVKEHQ LDVN Sbjct: 181 ESLHENVELLGTPWLQVYNNFPALLDYFPGIHKTLLKNADYIKNFIMEKVKEHQKLLDVN 240 Query: 259 NPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPE 318 NPRDFIDCFLIKMEQE + EF +E+LV V+DLF AGTETTSTTLRY LLLLLKHPE Sbjct: 241 NPRDFIDCFLIKMEQENNL---EFTLESLVIAVSDLFGAGTETTSTTLRYSLLLLLKHPE 297 Query: 319 VTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRN 378 V A+VQEEI+ VIGRHRSPCMQDRS MPYTDAV+HEIQR+ DL+PT +PHAVT D +FRN Sbjct: 298 VAARVQEEIERVIGRHRSPCMQDRSRMPYTDAVIHEIQRFIDLLPTNLPHAVTRDVRFRN 357 Query: 379 YLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGE 438 Y IPKGT I+ LTSVLHD+K FPNP +FDPGHFLD++GNFKKSDYFMPFSAGKR+C GE Sbjct: 358 YFIPKGTDIITSLTSVLHDEKAFPNPKVFDPGHFLDESGNFKKSDYFMPFSAGKRMCVGE 417 Query: 439 GLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIPV 490 GLARMELFLFLT+ILQNF L+S+ + K+L+ TAV G VS+PPSYQ+CFIP+ Sbjct: 418 GLARMELFLFLTSILQNFKLQSLVEPKDLDITAVVNGFVSVPPSYQLCFIPI 469 >3E6I-A nrPDB Length = 476 Score = 550 bits (1416), Expect = e-157, Method: Composition-based stats. Identities = 269/471 (57%), Positives = 351/471 (74%), Gaps = 1/471 (0%) Query: 19 LWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFH 78 + +++ + KLPPGP PLPIIGN+ Q+++K+I KSFT ++ +GPVFT+Y G +VV H Sbjct: 1 MAKKTSSKGKLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 60 Query: 79 GYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGK 138 GY+AVKEAL+D +EFSGRG+ P + GII +NG WK+IRRFSLTTLRN+GMGK Sbjct: 61 GYKAVKEALLDYKDEFSGRGDLPAF-HAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGK 119 Query: 139 RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM 198 + E R+Q EAH L+E LRKT+ P DPTF++GCAPCNVI ++F+K FDY D+ FL LM Sbjct: 120 QGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLM 179 Query: 199 KRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVN 258 FNENF +L++PW+Q+ NNFP + PG+H KV+KNVA + Y+ E+VKEH SLD N Sbjct: 180 YLFNENFHLLSTPWLQLYNNFPSFLHYLPGSHRKVIKNVAEVKEYVSERVKEHHQSLDPN 239 Query: 259 NPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPE 318 PRD DC L++ME+EK + + + ++ + TVADLF AGTETTSTTLRYGLL+L+K+PE Sbjct: 240 CPRDLTDCLLVEMEKEKHSAERLYTMDGITVTVADLFFAGTETTSTTLRYGLLILMKYPE 299 Query: 319 VTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRN 378 + K+ EEID VIG R P ++DR MPY DAVVHEIQR+ LVP+ +PH T DT FR Sbjct: 300 IEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRG 359 Query: 379 YLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGE 438 YLIPKGT ++ L SVL+D++EFP+P F P HFL++NG FK SDYF PFS GKR+CAGE Sbjct: 360 YLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFSTGKRVCAGE 419 Query: 439 GLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIP 489 GLARMELFL L ILQ+FNLK + D K+++ + + G +PP Y++C IP Sbjct: 420 GLARMELFLLLCAILQHFNLKPLVDPKDIDLSPIHIGFGCIPPRYKLCVIP 470 >4H1N-A nrPDB Length = 479 Score = 545 bits (1404), Expect = e-155, Method: Composition-based stats. Identities = 250/470 (53%), Positives = 343/470 (72%) Query: 19 LWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFH 78 + +++ + KLPPGP+PLP++GN+LQ+D K + +SF + YG VFTVY G P+VV Sbjct: 1 MAKKTSSKGKLPPGPSPLPVLGNLLQMDRKGLLRSFLRLREKYGDVFTVYLGSRPVVVLC 60 Query: 79 GYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGK 138 G +A++EAL+D E FSGRG + I +G G+I +NG+RW+ +RRFSL T+R+FGMGK Sbjct: 61 GTDAIREALVDQAEAFSGRGKIAVVDPIFQGYGVIFANGERWRALRRFSLATMRDFGMGK 120 Query: 139 RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM 198 RS+E+R+QEEA CLVEELRK+K + D T + N+ICS+VF KRFDYKD FL L+ Sbjct: 121 RSVEERIQEEARCLVEELRKSKGALLDNTLLFHSITSNIICSIVFGKRFDYKDPVFLRLL 180 Query: 199 KRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVN 258 F ++F +++S QV F + FPGTH ++ +N+ ++I + V++H+A+LD + Sbjct: 181 DLFFQSFSLISSFSSQVFELFSGFLKYFPGTHRQIYRNLQEINTFIGQSVEKHRATLDPS 240 Query: 259 NPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPE 318 NPRDFID +L++ME++K + SEF+ +NL+ TV LF AGTETTSTTLRYG LL+LK+P Sbjct: 241 NPRDFIDVYLLRMEKDKSDPSSEFHHQNLILTVLSLFAAGTETTSTTLRYGFLLMLKYPH 300 Query: 319 VTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRN 378 VT +VQ+EI+ VIG HR P + DR+ MPYTDAV+HEIQR DL+P GVPH VT DT+FR Sbjct: 301 VTERVQKEIEQVIGSHRPPALDDRAKMPYTDAVIHEIQRLGDLIPFGVPHTVTKDTQFRG 360 Query: 379 YLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGE 438 Y+IPK T + +L+S LHD + F PN F+PGHFLD NG K+++ FMPFS GKRIC GE Sbjct: 361 YVIPKNTEVFPVLSSALHDPRYFETPNTFNPGHFLDANGALKRNEGFMPFSLGKRICLGE 420 Query: 439 GLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFI 488 G+AR ELFLF TTILQNF++ S ++++ T G+ ++PPSYQI F+ Sbjct: 421 GIARTELFLFFTTILQNFSIASPVPPEDIDLTPRESGVGNVPPSYQIRFL 470 >2PG7-A nrPDB Length = 476 Score = 524 bits (1350), Expect = e-149, Method: Composition-based stats. Identities = 232/471 (49%), Positives = 321/471 (68%) Query: 19 LWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFH 78 + +++ + KLPPGPTPLP IGN LQ++ + + S S+ YGPVFT++ G +VV Sbjct: 1 MAKKTSSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 60 Query: 79 GYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGK 138 G++AV+EAL+D EEFSGRG + KG G++ SNG+R K++RRFS+ TLR+FG+GK Sbjct: 61 GHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGK 120 Query: 139 RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM 198 R IE+R+QEEA L++ LR T + DPTF L NVI S+VF RFDYKD+ FL+L+ Sbjct: 121 RGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLL 180 Query: 199 KRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVN 258 + F+ ++ Q+ F ++ PG + + + +I +KV+ +Q +LD N Sbjct: 181 RMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQLLQGLEDFIAKKVEHNQRTLDPN 240 Query: 259 NPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPE 318 +PRDFID FLI+M++E+ N +EF ++NLV T LFV GTET STTLRYG LLL+KHPE Sbjct: 241 SPRDFIDSFLIRMQEEEKNPNTEFYLKNLVMTTLQLFVGGTETVSTTLRYGFLLLMKHPE 300 Query: 319 VTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRN 378 V AKV EEID VIG++R P +DR+ MPY +AV+HEIQR+ D++P + V DTKFR+ Sbjct: 301 VEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRD 360 Query: 379 YLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGE 438 + +PKGT + +L SVL D F NP F+P HFL++ G FKKSD F+PFS GKR C GE Sbjct: 361 FFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGE 420 Query: 439 GLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIP 489 GLARMELFLF TT++QNF LKS K+++ + G ++P +Y + F+P Sbjct: 421 GLARMELFLFFTTVMQNFRLKSSQSPKDIDVSPKHVGFATIPRNYTMSFLP 471 >3IBD-A nrPDB Length = 476 Score = 523 bits (1348), Expect = e-149, Method: Composition-based stats. Identities = 240/471 (50%), Positives = 330/471 (70%) Query: 19 LWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFH 78 + +++ + KLPPGP PLP++GN+LQ+D + + KSF F + YG VFTV+ G P+V+ Sbjct: 1 MAKKTSSKGKLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDVFTVHLGPRPVVMLC 60 Query: 79 GYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGK 138 G EA++EAL+D E FSGRG + +G G+I +NG RWK +RRFS+TT+R+FGMGK Sbjct: 61 GVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGK 120 Query: 139 RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM 198 RS+E+R+QEEA CL+EELRK+K + DPTF+ N+ICS+VF KRF Y+DQ FL ++ Sbjct: 121 RSVEERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKML 180 Query: 199 KRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVN 258 F + F +++S + Q+ F + FPG H +V KN+ +YI V++H+ +LD + Sbjct: 181 NLFYQTFSLISSVFGQLFELFSGFLKHFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPS 240 Query: 259 NPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPE 318 PRD ID +L+ ME+EK N SEF+ +NL LF AGTETTSTTLRYG LL+LK+P Sbjct: 241 APRDLIDTYLLHMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPH 300 Query: 319 VTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRN 378 V +V EI+ VIG HR P + DR+ MPYT+AV++EIQR+SDL+P GVPH VT T FR Sbjct: 301 VAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSFRG 360 Query: 379 YLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGE 438 Y+IPK T + +L++ LHD F P+ F+P HFLD NG KK++ F+PFS GKRIC GE Sbjct: 361 YIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSLGKRICLGE 420 Query: 439 GLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIP 489 G+AR ELFLF TTILQNF++ S ++++ T G+ +PP+YQI F+P Sbjct: 421 GIARAELFLFFTTILQNFSMASPVAPEDIDLTPQECGVGKIPPTYQIRFLP 471 >5E0E-A nrPDB Length = 463 Score = 523 bits (1348), Expect = e-149, Method: Composition-based stats. Identities = 240/448 (53%), Positives = 325/448 (72%) Query: 41 NMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNS 100 N+LQ+D SF + YG VFTV+ G P+V+ +G EA++EAL+D E FSGRG Sbjct: 14 NLLQMDRGGFLNSFRRIREKYGDVFTVHLGPRPVVMLYGTEAIREALVDQAEAFSGRGTI 73 Query: 101 PISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTK 160 + + I +G G++ +NG+RWK +RRFSL T+R+FGMGKRS+E+R+QEEA CLVEE RK++ Sbjct: 74 AVVEPIFRGYGVVFANGERWKALRRFSLVTMRDFGMGKRSVEERIQEEARCLVEEFRKSQ 133 Query: 161 ASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFP 220 +P DPTF+ C N+ICS+VF +RFDYKD FL L+ F ++F +++S QV F Sbjct: 134 GAPLDPTFLFQCITANIICSIVFGERFDYKDHQFLRLLYLFYQSFSLISSFSSQVFELFS 193 Query: 221 LLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKS 280 + FPGTH ++ +N+ YI + V++H+A+LD ++PRDFID +L++ME+EK NQ + Sbjct: 194 GFLKYFPGTHRQISRNLQEILDYIGQSVEKHRATLDPSHPRDFIDTYLLRMEKEKSNQHT 253 Query: 281 EFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQ 340 EF+ +NLV +V LF AGTET+STTLRYG LL+LK+P V KVQ+EID VIG HR P ++ Sbjct: 254 EFDHQNLVISVLSLFFAGTETSSTTLRYGFLLMLKYPHVAEKVQKEIDQVIGSHRLPTLE 313 Query: 341 DRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKE 400 DR+ MPYT+AV++EIQR+SDL+P GVPH VT DT FR YL+PK T + +L+S LHD + Sbjct: 314 DRTKMPYTEAVIYEIQRFSDLIPIGVPHKVTKDTLFRGYLLPKNTEVYPILSSALHDPQY 373 Query: 401 FPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKS 460 F P+ F+P HFLD NG KKS+ FMPFS GKRIC GEG+AR ELFLF TTILQNF+L S Sbjct: 374 FEQPDTFNPDHFLDANGALKKSEAFMPFSIGKRICLGEGIARNELFLFFTTILQNFSLSS 433 Query: 461 VDDLKNLNTTAVTKGIVSLPPSYQICFI 488 K+++ + G +P +YQICF+ Sbjct: 434 PVAPKDIDLSPKESGFGKVPQTYQICFL 461 >5E58-A nrPDB Length = 493 Score = 523 bits (1347), Expect = e-149, Method: Composition-based stats. Identities = 239/448 (53%), Positives = 319/448 (71%) Query: 41 NMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNS 100 N+LQ+D SF + YG VFTV+ G P+V+ +G EA++EAL+D E FSGRG Sbjct: 42 NLLQMDRGGFLNSFMRIREKYGDVFTVHLGPRPVVMLYGTEAIREALVDQAEAFSGRGTI 101 Query: 101 PISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTK 160 + + + G+I SNG+RWK +RRFSL T+R+FGMGKRS+EDR+QEEA CLVEEL+K++ Sbjct: 102 AVIKPVIGDYGMIFSNGERWKVLRRFSLATMRDFGMGKRSVEDRIQEEAQCLVEELQKSQ 161 Query: 161 ASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFP 220 +P DPTF+ C N+ICS+VF +R+DYKD+ FL L+ F F +++S QV F Sbjct: 162 GAPLDPTFLFQCITANIICSIVFGERYDYKDRQFLRLLDLFYRTFSLMSSFSSQVFELFS 221 Query: 221 LLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKS 280 + FPG H ++ +N+ Y+ + V++H+A+LD +NPRDFID +L++ME+EK NQ + Sbjct: 222 GFMKYFPGAHRQITRNLQEILDYVGQSVEKHRATLDPSNPRDFIDTYLLRMEKEKSNQHT 281 Query: 281 EFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQ 340 EF+ +NL+ +V LF AGTETTSTTLRYG LL+LK+P V KVQ+EID VIG HR P ++ Sbjct: 282 EFHHQNLLISVLSLFFAGTETTSTTLRYGFLLMLKYPHVAEKVQKEIDQVIGSHRLPTLE 341 Query: 341 DRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKE 400 DR+ MPYTDAV+HEIQR+SDL P G PH VT DT FR YL+PK T + +L+S LHD + Sbjct: 342 DRTKMPYTDAVIHEIQRFSDLAPIGAPHKVTKDTLFRGYLLPKNTEVYPILSSALHDPQY 401 Query: 401 FPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKS 460 F P F+P HFLD NG KKS+ FMPFS GKRIC GEG+AR ELFLF TTILQNF++ S Sbjct: 402 FEQPGTFNPDHFLDANGALKKSEAFMPFSIGKRICLGEGIARNELFLFFTTILQNFSVSS 461 Query: 461 VDDLKNLNTTAVTKGIVSLPPSYQICFI 488 K+++ + GI +P +YQI F+ Sbjct: 462 SVAPKDIDLSPKESGIGKVPQTYQISFL 489 >6B82-A nrPDB Length = 509 Score = 437 bits (1125), Expect = e-123, Method: Composition-based stats. Identities = 144/491 (29%), Positives = 246/491 (50%), Gaps = 27/491 (5%) Query: 19 LWRQSCRRRK-------------LPPGPTPLPIIGNMLQI-DVKDICKSFTNFSKVYGPV 64 + +++ + K PP LPIIG+++ + F + K YG + Sbjct: 1 MAKKTSSKGKKQKMNGFVPAGNRSPPSLPSLPIIGSLMSLVSDSPPHIFFQDLQKKYGDL 60 Query: 65 FTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITK-GLGIISSN-GKRWKE 122 +++ G + +++ + + KE LI G+ F+GR + + +T+ G I ++ WK Sbjct: 61 YSLMMGSHKLLIVNNHHHAKEILIKKGKIFAGRPRTVTTDLLTRDGKDIAFADYSSTWKF 120 Query: 123 IRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVV 182 R+ L FG G SIE + EA + E L +++ S D L A NV+C++ Sbjct: 121 HRKMVHGALCMFGEGSVSIEKIICREASSMCEVLTESQNSAVDLGPELTRAVTNVVCALC 180 Query: 183 FQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRS 242 F + D F ++++ + + + FP L FP ++L+ R Sbjct: 181 FNSSYKRGDAEFESMLQYSQGIVDTVAK--DSLVDIFPWL-QIFPNKDLRILRQCISIRD 237 Query: 243 -YIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSE----FNIENLVGTVADLFVA 297 +++K +EH+ + N RD +D L ++N S ++++ TV ++F A Sbjct: 238 KLLQKKYEEHKVTYSDNVQRDLLDALLRAKRSSENNNSSTRDVGLTEDHVLMTVGEIFGA 297 Query: 298 GTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQR 357 G ETT+TTL++ + L+ +P+V K+QEE+D IG+ R P + DR ++PY +A + E+ R Sbjct: 298 GVETTTTTLKWSIAYLVHNPQVQRKIQEELDSKIGKERHPQLSDRGNLPYLEATICEVMR 357 Query: 358 YSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNG 417 + P +PH D+ Y + KGT ++ + S+ HD+KE+ NP +FDPG FL++ G Sbjct: 358 IRPVSPLLIPHVALQDSSVGEYTVQKGTRVVINMWSLHHDEKEWKNPELFDPGRFLNEEG 417 Query: 418 NFK--KSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKG 475 + S ++PF AG R+C GE LA+MELFLFL ILQ F L+ L G Sbjct: 418 DGLCCPSGSYLPFGAGVRVCLGEALAKMELFLFLAWILQRFTLEMPTGQP-LPDLQGKFG 476 Query: 476 IVSLPPSYQIC 486 +V P +++ Sbjct: 477 VVLQPKKFKVV 487 >3TBG-A nrPDB Length = 479 Score = 428 bits (1101), Expect = e-120, Method: Composition-based stats. Identities = 199/476 (41%), Positives = 285/476 (59%), Gaps = 7/476 (1%) Query: 19 LWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFH 78 + +++ + KLPPGP PLP +GN+L +D ++ F + +G VF++ P+VV + Sbjct: 1 MAKKTSSKGKLPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLN 60 Query: 79 GYEAVKEALIDNGEEFSGRGNSPISQRITKGLG----IISSNGKRWKEIRRFSLTTLRNF 134 G AV+EAL+ +GE+ + R PI+Q + G ++ G W+E RRFS++TLRN Sbjct: 61 GLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNL 120 Query: 135 GMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNF 194 G+GK+S+E V EEA CL P P +L A NVI S+ +RF+Y D F Sbjct: 121 GLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRF 180 Query: 195 LTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQAS 254 L L+ E + + +V N P+L+ P KVL+ + + E + EH+ + Sbjct: 181 LRLLDLAQEGLKEESGFLREVLNAVPVLLHI-PALAGKVLRFQKAFLTQLDELLTEHRMT 239 Query: 255 LDV-NNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLL 313 D PRD + FL +ME+ K N +S FN ENL VADLF AG TTSTTL +GLLL+ Sbjct: 240 WDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLM 299 Query: 314 LKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTD 373 + HP+V +VQ+EID VIG+ R P M D++HMPYT AV+HE+QR+ D+VP GV H + D Sbjct: 300 ILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRD 359 Query: 374 TKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKR 433 + + + IPKGTT++ L+SVL D+ + P F P HFLD G+F K + F+PFSAG+R Sbjct: 360 IEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRR 419 Query: 434 ICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIP 489 C GE LARMELFLF T++LQ+F+ + V +VS P Y++C +P Sbjct: 420 ACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVS-PSPYELCAVP 474 >3DL9-A nrPDB Length = 479 Score = 421 bits (1082), Expect = e-118, Method: Composition-based stats. Identities = 152/438 (34%), Positives = 251/438 (57%), Gaps = 3/438 (0%) Query: 50 ICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKG 109 S+VYG +F++ G VV +GY+ VKE L+ E F+ R P+ ++TK Sbjct: 36 PHVYMRKQSQVYGEIFSLDLGGISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMTKM 95 Query: 110 LGIISS-NGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTF 168 G+++S G+ W + RR ++ + R FG G++S E ++ EE + + K P D Sbjct: 96 GGLLNSRYGRGWVDHRRLAVNSFRYFGYGQKSFESKILEETKFFNDAIETYKGRPFDFKQ 155 Query: 169 ILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPG 228 ++ A N+ ++F +RF Y+D +F +++ F+EN + S + + N FP + G Sbjct: 156 LITNAVSNITNLIIFGERFTYEDTDFQHMIELFSENVELAASASVFLYNAFPWIGILPFG 215 Query: 229 THNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLV 288 H ++ +N A+ ++ +++ + P+ F+D +L +M+Q K++ S F+ ENL+ Sbjct: 216 KHQQLFRNAAVVYDFLSRLIEKASVNRKPQLPQHFVDAYLDEMDQGKNDPSSTFSKENLI 275 Query: 289 GTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYT 348 +V +L +AGTETT+ LR+ +L + +P + +VQ+EID ++G + P D+ MPYT Sbjct: 276 FSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCKMPYT 335 Query: 349 DAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFD 408 +AV+HE+ R+ ++VP G+ HA + D R Y IPKGTT++ L SV D+K + +P +F Sbjct: 336 EAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFH 395 Query: 409 PGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLN 468 P FLD +G F K + +PFS G+R C GE LARME+FLF T +LQ F+L +L + Sbjct: 396 PERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHFPHEL--VP 453 Query: 469 TTAVTKGIVSLPPSYQIC 486 G+ P Y IC Sbjct: 454 DLKPRLGMTLQPQPYLIC 471 >4R20-A nrPDB Length = 486 Score = 414 bits (1063), Expect = e-116, Method: Composition-based stats. Identities = 150/483 (31%), Positives = 233/483 (48%), Gaps = 17/483 (3%) Query: 19 LWRQSCRRRKLPPGPTP--LPIIGNMLQIDVK-------DICKSFTNFSKVYGPVFTVYF 69 + +++ + K G + P + + + FT S YGP+F +Y Sbjct: 1 MAKKTSSKGKEGVGSSSVSFPCLPRLPLLGSLLHLRSNLPPHLLFTQLSSQYGPLFGLYA 60 Query: 70 GMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIIS--SNGKRWKEIRRFS 127 G + +V V+E L+ G EF+GR + +T+G I+ WK RR Sbjct: 61 GPHLTLVVSEIGLVREVLLQRGREFAGRPKMVTTDLLTQGGKDIAFADYSPLWKNHRRLV 120 Query: 128 LTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRF 187 ++ FG G ++ VQE A L EEL+ + D + +L A NVIC +VF + Sbjct: 121 HSSFTLFGEGSNKLQTIVQEAADSLCEELQACRGQSSDLSVVLMRAVTNVICRLVFSSSY 180 Query: 188 DYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRS-YIRE 246 D T+++ + + + + + FP L FP K LK R + + Sbjct: 181 QPSDPELQTVIQYNDGIVQTIA--RGGLVDIFPWL-RIFPNKDLKRLKECVSIRDQLLYK 237 Query: 247 KVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTL 306 K+ EH+ SL PRD +D LI +Q + ++++ T A+ F AG ETTSTTL Sbjct: 238 KLLEHKKSLTPGEPRDLLDALLIG-QQRGSGGADDITEDHVLMTAAEAFGAGVETTSTTL 296 Query: 307 RYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGV 366 + + LL HP++ +VQ E+D +G R PC+ DR H+P DAV+ E+ R + P + Sbjct: 297 LWTIAFLLHHPQLQERVQAELDECVGVDRPPCLSDRPHLPLLDAVLCEVMRIRPVSPILI 356 Query: 367 PHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFM 426 PH DT + +PKGT ++ + ++ HD K + P F+P FL+ +G K F+ Sbjct: 357 PHVAMQDTSLGGHSVPKGTRVLVNMWAIHHDPKHWDQPEQFNPERFLEPSGKKKTQSSFL 416 Query: 427 PFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQIC 486 PF AG R+C GE LAR+ELFLF++ LQ F+ S +L G+V P Y + Sbjct: 417 PFGAGPRVCVGESLARIELFLFVSRPLQRFSF-SCPSEASLPDLQGRFGVVLQPERYTVT 475 Query: 487 FIP 489 P Sbjct: 476 VTP 478 >6DWN-A nrPDB Length = 491 Score = 411 bits (1057), Expect = e-115, Method: Composition-based stats. Identities = 141/464 (30%), Positives = 241/464 (51%), Gaps = 21/464 (4%) Query: 19 LWRQSCRRR-KLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVF 77 + +++ + K PPGP P+IG+ML + K+ + + S+ YG V + G P+VV Sbjct: 1 MAKKTSSKGLKNPPGPWGWPLIGHMLTLG-KNPHLALSRMSQQYGDVLQIRIGSTPVVVL 59 Query: 78 HGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISS--NGKRWKEIRRFSLTTLRNFG 135 G + +++AL+ G++F GR + I+ G + S +G W RR + L++F Sbjct: 60 SGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFS 119 Query: 136 MGKRS-------IEDRVQEEAHCLVEELRKTKASP--CDPTFILGCAPCNVICSVVFQKR 186 + +E+ V +EA L+ L++ A P +P + + NVIC++ F +R Sbjct: 120 IASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRR 179 Query: 187 FDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALT-RSYIR 245 +D+ Q L+L+ N ++ S +F ++ P K++ S+++ Sbjct: 180 YDHNHQELLSLVNLNNNFGEVVGSG---NPADFIPILRYLPNPSLNAFKDLNEKFYSFMQ 236 Query: 246 EKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKS--EFNIENLVGTVADLFVAGTETTS 303 + VKEH + + + RD D + ++++ ++ + + + E ++ V DLF AG +T + Sbjct: 237 KMVKEHYKTFEKGHIRDITDSLIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVT 296 Query: 304 TTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVP 363 T + + L+ L+ +P V K+QEE+D VIGR R P + DRSH+PY +A + E R+S VP Sbjct: 297 TAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVP 356 Query: 364 TGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKK-- 421 +PH+ T DT + + IPKG + + HD K + NP+ F P FL +G K Sbjct: 357 FTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVL 416 Query: 422 SDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLK 465 S+ + F GKR C GE +AR E+FLFL +LQ +K Sbjct: 417 SEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVEFSVPLGVK 460 >2HI4-A nrPDB Length = 495 Score = 389 bits (998), Expect = e-108, Method: Composition-based stats. Identities = 135/466 (28%), Positives = 221/466 (47%), Gaps = 19/466 (4%) Query: 15 LLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPI 74 +L L + + K PP P P++G++L + K+ + + S+ YG V + G P+ Sbjct: 3 VLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLG-KNPHLALSRMSQRYGDVLQIRIGSTPV 61 Query: 75 VVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISS--NGKRWKEIRRFSLTTLR 132 +V + +++AL+ G++F GR + S IT G + S +G W RR + L Sbjct: 62 LVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALN 121 Query: 133 NFGMGKRS-------IEDRVQEEAHCLVEELRKTKASP--CDPTFILGCAPCNVICSVVF 183 F + +E+ V +EA L+ L++ A P DP + + NVI ++ F Sbjct: 122 TFSIASDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANVIGAMCF 181 Query: 184 QKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNV-ALTRS 242 + F L+L+K +E +S + FP+L P + K Sbjct: 182 GQHFPESSDEMLSLVKNTHEFVETASSG--NPLDFFPIL-RYLPNPALQRFKAFNQRFLW 238 Query: 243 YIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETT 302 ++++ V+EH D N+ RD ++ + E +V V D+F AG +T Sbjct: 239 FLQKTVQEHYQDFDKNSVRDITGALFKHSKKGPRASGNLIPQEKIVNLVNDIFGAGFDTV 298 Query: 303 STTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLV 362 +T + + L+ L+ PE+ K+Q+E+D VIGR R P + DR +PY +A + E R+S + Sbjct: 299 TTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHSSFL 358 Query: 363 PTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNG---NF 419 P +PH+ T DT + IPK + V HD + + +P+ F P FL +G N Sbjct: 359 PFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTAINK 418 Query: 420 KKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLK 465 S+ M F GKR C GE LA+ E+FLFL +LQ +K Sbjct: 419 PLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSVPPGVK 464 >4R1Z-A nrPDB Length = 439 Score = 388 bits (997), Expect = e-108, Method: Composition-based stats. Identities = 133/427 (31%), Positives = 217/427 (50%), Gaps = 13/427 (3%) Query: 69 FGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITK-GLGIISSN-GKRWKEIRRF 126 G + +++ + + KE LI G+ F+GR + + +T+ G I ++ WK R+ Sbjct: 1 MGSHKLLIVNNHHHAKEILIKKGKIFAGRPRTVTTDLLTRDGKDIAFADYSSTWKFHRKM 60 Query: 127 SLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKR 186 L FG G SIE + EA + E L +++ S D L A NV+C++ F Sbjct: 61 VHGALCMFGEGSVSIEKIICREASSMCEVLTESQNSAVDLGPELTRAVTNVVCALCFNSS 120 Query: 187 FDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRS-YIR 245 + D F ++++ + + + FP L FP +L+ R ++ Sbjct: 121 YKRGDAEFESMLQYSQGIVDTVAK--DSLVDIFPWL-QIFPNKDLTILRQCISIRDKLLQ 177 Query: 246 EKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSE----FNIENLVGTVADLFVAGTET 301 +K +EH+ + N RD +D L ++N S ++++ TV D+F AG ET Sbjct: 178 KKYEEHKVTYSDNVQRDLLDALLRAKRSSENNNSSTRDVGLTEDHVLMTVGDIFGAGVET 237 Query: 302 TSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDL 361 T+T L++ + L+ +P+V K+QEE+D IG+ R P + DR ++PY +A + E+ R + Sbjct: 238 TTTVLKWSIAYLVHNPQVQRKIQEELDSKIGKERHPQLSDRGNLPYLEATIREVLRIRPV 297 Query: 362 VPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFK- 420 P +PH D+ Y + KGT ++ L S+ HD KE+ NP +FDPG FL++ G+ Sbjct: 298 SPLLIPHVALQDSSVGEYTVQKGTRVVINLWSLHHDKKEWKNPELFDPGRFLNEEGDGLC 357 Query: 421 -KSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSL 479 S ++PF AG R+C GE LA+MELFLFL ILQ F L+ L G+V Sbjct: 358 CPSGSYLPFGAGVRVCLGEALAKMELFLFLAWILQRFTLEMPTGQP-LPDLQGKFGVVLQ 416 Query: 480 PPSYQIC 486 P +++ Sbjct: 417 PKKFKVV 423 >5UYS-A nrPDB Length = 494 Score = 387 bits (993), Expect = e-108, Method: Composition-based stats. Identities = 124/457 (27%), Positives = 221/457 (48%), Gaps = 17/457 (3%) Query: 19 LWRQSCRRRKLPPGPTPLPIIGNMLQIDVKD-ICKSFTNFSKVYGPVFTVYFGMNPIVVF 77 + +++ K P LP++G++ + + +F K YGP+++V G V+ Sbjct: 1 MAKKT--GAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIV 58 Query: 78 HGYEAVKEALIDNGEEFSGRGNSPISQRITKGL-GIISSN-GKRWKEIRRFSLTTLRNFG 135 ++ KE LI G++FSGR + GI ++ G W+ RR ++ T F Sbjct: 59 GHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRKGIAFADSGAHWQLHRRLAMATFALFK 118 Query: 136 MGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFL 195 G + +E + +E L + L D +F + A NVI + F + D L Sbjct: 119 DGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPE-L 177 Query: 196 TLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTR-SYIREKVKEHQAS 254 +++ +NE I N + + P L FP + LK+ R + + ++ ++ Sbjct: 178 NVIQNYNEGI-IDNLSKDSLVDLVPWL-KIFPNKTLEKLKSHVKIRNDLLNKILENYKEK 235 Query: 255 LDVNNPRDFIDCFLIK-MEQEKDNQKSEFNIE-----NLVGTVADLFVAGTETTSTTLRY 308 ++ + +D + M + N + + E +++ T+ D+F AG ETT++ +++ Sbjct: 236 FRSDSITNMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKW 295 Query: 309 GLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPH 368 L LL +P+V K+ EEID +G R+P + DR+ + +A + E+ R + P +PH Sbjct: 296 TLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPH 355 Query: 369 AVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGN--FKKSDYFM 426 D+ + + KGT ++ L ++ H++KE+ P+ F P FL+ G S ++ Sbjct: 356 KANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYL 415 Query: 427 PFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDD 463 PF AG R C GE LAR ELFL + +LQ F+L+ DD Sbjct: 416 PFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDD 452 >5VBU-A nrPDB Length = 476 Score = 376 bits (965), Expect = e-104, Method: Composition-based stats. Identities = 125/479 (26%), Positives = 219/479 (45%), Gaps = 23/479 (4%) Query: 19 LWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFH 78 + +++ + KLP P+ L + D+ ++ +GP++ ++ G+ +VV + Sbjct: 1 MAKKTSSKGKLP------PLAPGFLHLLQPDLPIYLLGLTQKFGPIYRLHLGLQDVVVLN 54 Query: 79 GYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGK--RWKEIRRFSLTTLRNFGM 136 ++EA++ +F+GR + +++ +S WK ++ + + L Sbjct: 55 SKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYPDLSLGDYSLLWKAHKKLTRSALLL--G 112 Query: 137 GKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLT 196 + S+E V++ E +R +P C++IC + F + KD N + Sbjct: 113 IRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTCSIICYLTFGDKI--KDDNLMP 170 Query: 197 LMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREK-VKEHQASL 255 + + S W + + FP + LK R +I E +++H+ SL Sbjct: 171 AYYKCIQEVLKTWSHWSIQIVDVIPFLRFFPNPGLRRLKQAIEKRDHIVEMQLRQHKESL 230 Query: 256 DVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTV-ADLFVAGTETTSTTLRYGLLLLL 314 RD +D L + Q + S +E V DL + GTETT+ TL + ++ LL Sbjct: 231 VAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLSWAVVFLL 290 Query: 315 KHPEVTAKVQEEIDHVIGRHRSPC---MQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVT 371 HPE+ ++QEE+DH +G S +DR+ +P +A + E+ R +VP +PH T Sbjct: 291 HHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTT 350 Query: 372 TDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAG 431 + Y IP+GT I+ L D+ + P+ F P FL+ N + + F G Sbjct: 351 RPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSRA----LAFGCG 406 Query: 432 KRICAGEGLARMELFLFLTTILQNFN-LKSVDDLKNLNTTAVTKGIVSLPPSYQICFIP 489 R+C GE LAR+ELF+ LT +LQ F L S D L +L I+ + P +Q+ P Sbjct: 407 ARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALPSLQPLPHCSVILKMQP-FQVRLQP 464 >6IQ5-A nrPDB Length = 463 Score = 357 bits (916), Expect = 7e-99, Method: Composition-based stats. Identities = 142/459 (30%), Positives = 230/459 (50%), Gaps = 29/459 (6%) Query: 51 CKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGL 110 SF ++ YG VF + G PIVV +G A+ +AL+ G F+ R + + ++ G Sbjct: 4 HLSFARLARRYGDVFQIRLGSCPIVVLNGERAIHQALVQQGSAFADRPSFASFRVVSGGR 63 Query: 111 GIISSN-GKRWKEIRRFSLTTLRNF----GMGKRSIEDRVQEEAHCLVEELRKTK--ASP 163 + + + WK RR + + +RNF ++ +E V EA LV L + + Sbjct: 64 SMAFGHYSEHWKVQRRAAHSMMRNFFTRQPRSRQVLEGHVLSEARELVALLVRGSADGAF 123 Query: 164 CDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNS-------PWIQVC 216 DP + A NV+ +V F R+ + D F L+ E R + + PW+Q Sbjct: 124 LDPRPLTVVAVANVMSAVCFGCRYSHDDPEFRELLSHNEEFGRTVGAGSLVDVMPWLQ-- 181 Query: 217 NNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNN-PRDFIDCFLIKMEQ-- 273 FP + ++ +N + ++I +K H SL PRD +D F++ E+ Sbjct: 182 -YFPNPVRTVFREFEQLNRNFS---NFILDKFLRHCESLRPGAAPRDMMDAFILSAEKKA 237 Query: 274 --EKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVI 331 + + ++EN+ T+ D+F A +T ST L++ LLL ++P+V +VQ E+D V+ Sbjct: 238 AGDSHGGGARLDLENVPATITDIFGASQDTLSTALQWLLLLFTRYPDVQTRVQAELDQVV 297 Query: 332 GRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALL 391 GR R PCM D+ ++PY A ++E R+S VP +PHA T +T Y IPK T + Sbjct: 298 GRDRLPCMGDQPNLPYVLAFLYEAMRFSSFVPVTIPHATTANTSVLGYHIPKDTVVFVNQ 357 Query: 392 TSVLHDDKEFPNPNIFDPGHFLDKNGNFKK--SDYFMPFSAGKRICAGEGLARMELFLFL 449 SV HD ++PNP FDP FLDK+G K + M FS GKR C GE L++M+LFLF+ Sbjct: 358 WSVNHDPVKWPNPENFDPARFLDKDGLINKDLTSRVMIFSVGKRRCIGEELSKMQLFLFI 417 Query: 450 TTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFI 488 + + + ++ + + G+ P S+++ Sbjct: 418 SILAHQCDFRANPNEPA--KMNFSYGLTIKPKSFKVNVT 454 >5YLW-A nrPDB Length = 495 Score = 355 bits (910), Expect = 3e-98, Method: Composition-based stats. Identities = 121/501 (24%), Positives = 224/501 (44%), Gaps = 26/501 (5%) Query: 3 PFVVLVLCLSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYG 62 P + + ++ + F +R RRR LPPGP P PI+GNMLQ+ + + F SK YG Sbjct: 5 PLLAALFFIAATITFLSFR---RRRNLPPGPFPYPIVGNMLQLGA-NPHQVFAKLSKRYG 60 Query: 63 PVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPIS-----QRITKGLGIISSNG 117 P+ +++ G V+ E KE L +G+ FSGR + +I+ G ++S Sbjct: 61 PLMSIHLGSLYTVIVSSPEMAKEILHRHGQVFSGRTIAQAVHACDHDKISMGFLPVASE- 119 Query: 118 KRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTK--ASPCDPTFILGCAPC 175 W+++R+ + + + + +++ L++ ++K D Sbjct: 120 --WRDMRKICKEQMFS-NQSMEASQGLRRQKLQQLLDHVQKCSDSGRAVDIREAAFITTL 176 Query: 176 NVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVL- 234 N++ + +F + D K E + + FP+L P + Sbjct: 177 NLMSATLFSSQATEFDSKATMEFKEIIEGVATI-VGVPNFADYFPILRPFDPQGVKRRAD 235 Query: 235 ----KNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGT 290 K +A Y+ E+++ +A+ + DF++ + ++ + + + Sbjct: 236 VFFGKLLAKIEGYLNERLESKRANPNAPKKDDFLEIVVDIIQA----NEFKLKTHHFTHL 291 Query: 291 VADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDA 350 + DLFV G++T +T++ + + L+ +P+ A+++ E+ V G + +PY A Sbjct: 292 MLDLFVGGSDTNTTSIEWAMSELVMNPDKMARLKAELKSVAGDEKIVDESAMPKLPYLQA 351 Query: 351 VVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPG 410 V+ E+ R P +P +D + YLIPKGT I+ ++ D + +P FDP Sbjct: 352 VIKEVMRIHPPGPLLLPRKAESDQEVNGYLIPKGTQILINAYAIGRDPSIWTDPETFDPE 411 Query: 411 HFLDKNGNFKKSDY-FMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNT 469 FLD +FK DY +PF +G+R+C G LA L + T++ NF+ K DD Sbjct: 412 RFLDNKIDFKGQDYELLPFGSGRRVCPGMPLATRILHMATATLVHNFDWKLEDDSTAAAD 471 Query: 470 TAVTKGIVSLPPSYQICFIPV 490 A V++ + + IP+ Sbjct: 472 HAGELFGVAVRRAVPLRIIPI 492 >3QZ1-A nrPDB Length = 496 Score = 349 bits (894), Expect = 2e-96, Method: Composition-based stats. Identities = 122/466 (26%), Positives = 209/466 (44%), Gaps = 28/466 (6%) Query: 37 PIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSG 96 P++ L + ++ + ++ GPV+ + G+ +VV + ++EA+I +F+G Sbjct: 32 PLVPGFLHLLQPNLPIHLLSLTQKLGPVYRLRLGLQEVVVLNSKRTIEEAMIRKWVDFAG 91 Query: 97 RGNSPISQRITKGLGIISSNGK--RWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVE 154 R P + +++ IS WK ++ + + L S+E V + E Sbjct: 92 RPQIPSYKLVSQRCQDISLGDYSLLWKAHKKLTRSALLLGTRS--SMEPWVDQLTQEFCE 149 Query: 155 ELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPW-- 212 +R +P C++IC + F + D TL+ F++ + L W Sbjct: 150 RMRVQAGAPVTIQKEFSLLTCSIICYLTFGNKED-------TLVHAFHDCVQDLMKTWDH 202 Query: 213 --IQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREK-VKEHQASLDVNNPRDFIDCFLI 269 IQ+ + P L FP LK R ++ EK ++ H+ S+ RD D L Sbjct: 203 WSIQILDMVPFL-RFFPNPGLWRLKQAIENRDHMVEKQLRRHKESMVAGQWRDMTDYMLQ 261 Query: 270 KMEQEKDNQKSEFNIENLVGT-VADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEID 328 + +++ + +E V V DLF+ GTETT++TL + + LL HPE+ ++QEE+D Sbjct: 262 GVGRQRVEEGPGQLLEGHVHMSVVDLFIGGTETTASTLSWAVAFLLHHPEIQRRLQEELD 321 Query: 329 HVIGRHRS---PCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGT 385 +G S +DR+ +P +A + E+ R +VP +PH T + Y IP+G Sbjct: 322 RELGPGASCSRVTYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSIFGYDIPEGM 381 Query: 386 TIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMEL 445 ++ L D+ + P+ F P FL+ N + F G R+C GE LAR+EL Sbjct: 382 VVIPNLQGAHLDETVWEQPHEFRPDRFLEPGAN----PSALAFGCGARVCLGESLARLEL 437 Query: 446 FLFLTTILQNFNLKSVD--DLKNLNTTAVTKGIVSLPPSYQICFIP 489 F+ L +LQ F L L +L G+ +Q+ P Sbjct: 438 FVVLARLLQAFTLLPPPVGALPSLQPDPYC-GVNLKVQPFQVRLQP 482 >6DA2-A nrPDB Length = 487 Score = 346 bits (888), Expect = 1e-95, Method: Composition-based stats. Identities = 117/457 (25%), Positives = 181/457 (39%), Gaps = 19/457 (4%) Query: 16 LFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIV 75 L+ ++ PGPTPLP +GN+L K C K YG V+ Y G P++ Sbjct: 4 LYGTHSHGLFKKLGIPGPTPLPFLGNILSYH-KGFCMFDMECHKKYGKVWGFYDGQQPVL 62 Query: 76 VFHGYEAVKEALIDNGEE-FSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNF 134 + +K L+ F+ R P I + + WK +R T F Sbjct: 63 AITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLSPT---F 117 Query: 135 GMGK-RSIEDRVQEEAHCLVEELRKTK--ASPCDPTFILGCAPCNVICSVVFQKRFDYKD 191 GK + + + + LV LR+ P + G +VI S F D + Sbjct: 118 TSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLN 177 Query: 192 QNFLTLMKRFNENFRI-LNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKE 250 ++ + R P+ FP LI + V +++R+ VK Sbjct: 178 NPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFP--REVTNFLRKSVKR 235 Query: 251 HQASLDVNNPRDFIDCFLIKMEQEKDNQKSE----FNIENLVGTVADLFVAGTETTSTTL 306 + S + + +D FL M ++++++E + LV AG ETTS+ L Sbjct: 236 MKESRLEDTQKHRVD-FLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVL 294 Query: 307 RYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGV 366 + + L HP+V K+QEEID V+ P M Y D VV+E R + + Sbjct: 295 SFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIA-MRL 353 Query: 367 PHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFM 426 D + IPKG +M ++ D K + P F P F KN + + Sbjct: 354 ERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYT 413 Query: 427 PFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDD 463 PF +G R C G A M + L L +LQNF+ K + Sbjct: 414 PFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKE 450 >5VEU-A nrPDB Length = 480 Score = 344 bits (881), Expect = 8e-95, Method: Composition-based stats. Identities = 113/459 (24%), Positives = 182/459 (39%), Gaps = 20/459 (4%) Query: 14 MLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNP 73 M L+ +R PGPTPLP++GN+L + + K T K YG ++ Y G P Sbjct: 1 MALYGTRTHGLFKRLGIPGPTPLPLLGNVLSY-RQGLWKFDTECYKKYGKMWGTYEGQLP 59 Query: 74 IVVFHGYEAVKEALIDNGEE-FSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLR 132 ++ + ++ L+ F+ R + I + + WK IR T Sbjct: 60 VLAITDPDVIRTVLVKECYSVFTNRRSL--GPVGFMKSAISLAEDEEWKRIRSLLSPT-- 115 Query: 133 NFGMGK-RSIEDRVQEEAHCLVEELRKT--KASPCDPTFILGCAPCNVICSVVFQKRFDY 189 F GK + + + + LV LR+ K P I G +VI F D Sbjct: 116 -FTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDS 174 Query: 190 KDQNFLTLMKRFNENFRI-LNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKV 248 + ++ + + P FP L F + + + +++ + V Sbjct: 175 LNNPQDPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSLFPKDTI--NFLSKSV 232 Query: 249 KEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSE----FNIENLVGTVADLFVAGTETTST 304 + S + + +D FL M ++++++E + L AG ETTS+ Sbjct: 233 NRMKKSRLNDKQKHRLD-FLQLMIDSQNSKETESHKALSDLELAAQSIIFIFAGYETTSS 291 Query: 305 TLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPT 364 L + L L HP+V K+Q+EID V+ P M Y D VV+E R V Sbjct: 292 VLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFP-VAI 350 Query: 365 GVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDY 424 + D + IPKG+ ++ ++ HD K + P F P F K + Sbjct: 351 RLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDSI-DPYI 409 Query: 425 FMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDD 463 + PF G R C G A M + L L +LQNF+ K + Sbjct: 410 YTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKE 448 >3K9V-A nrPDB Length = 482 Score = 277 bits (708), Expect = 9e-75, Method: Composition-based stats. Identities = 101/469 (21%), Positives = 190/469 (40%), Gaps = 32/469 (6%) Query: 31 PGPTPLPIIGNMLQIDVKDICK----SFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEA 86 PGPT P++G++L+I K K + + K YG +F + G V G ++ EA Sbjct: 27 PGPTNWPLLGSLLEIFWKGGLKKQHDTLAEYHKKYGQIFRMKLGSFDSVHL-GSPSLLEA 85 Query: 87 LIDNGEEFSGR----GNSPISQRITKGLGIISSNGKRWKEIRR-FSLTTLRNFGMGKRSI 141 L R + G++ G+ W+ +R F ++ + K + Sbjct: 86 LYRTESAHPQRLEIKPWKAYRDHRNEAYGLMILEGQEWQRVRSAFQKKLMKPVEIMK--L 143 Query: 142 EDRVQEEAHCLVE---ELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM 198 + ++ E +E EL + D L IC V+++KRF + Sbjct: 144 DKKINEVLADFLERMDELCDERGRIPDLYSELNKWSFESICLVLYEKRFGLLQKETEEEA 203 Query: 199 KRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVK---EHQASL 255 F + + S + ++ ++ + KV + L I + VK +++ Sbjct: 204 LTFITAIKTMMSTFGKMMVT---PVELHKRLNTKVWQAHTLAWDTIFKSVKPCIDNRLQR 260 Query: 256 DVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLK 315 P C + Q+ + + L V +L +A ETT+ +L + L L + Sbjct: 261 YSQQPGADFLCDI--------YQQDHLSKKELYAAVTELQLAAVETTANSLMWILYNLSR 312 Query: 316 HPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTK 375 +P+ ++ +E+ V+ +++P +D +MPY A + E R + VP + T Sbjct: 313 NPQAQRRLLQEVQSVLPDNQTPRAEDLRNMPYLKACLKESMRLTPSVPFTT-RTLDKPTV 371 Query: 376 FRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRIC 435 Y +PKGT + + + F + + F P +L K +PF GKR+C Sbjct: 372 LGEYALPKGTVLTLNTQVLGSSEDNFEDSHKFRPERWLQKEKKI-NPFAHLPFGIGKRMC 430 Query: 436 AGEGLARMELFLFLTTILQNFNLKSVDDLK-NLNTTAVTKGIVSLPPSY 483 G LA ++L L L I+Q +++ + D+ + + LP ++ Sbjct: 431 IGRRLAELQLHLALCWIIQKYDIVATDNEPVEMLHLGILVPSRELPIAF 479 >3MDV-A nrPDB Length = 456 Score = 271 bits (693), Expect = 4e-73, Method: Composition-based stats. Identities = 97/423 (22%), Positives = 169/423 (39%), Gaps = 30/423 (7%) Query: 54 FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALID---NGEEFSGRGNSPISQRITKGL 110 F +++K YGPV V V+ E+VK+ L+ N + R + G Sbjct: 16 FLDWAKKYGPVVRVNVFHKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFGQ 75 Query: 111 GIISS-NGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVE--ELRKTKASPCDPT 167 G++S N +RW + RR + S+ + E+A LVE E + +P Sbjct: 76 GLVSECNYERWHKQRRVIDLAFSRSSL--VSLMETFNEKAEQLVEILEAKADGQTPVSMQ 133 Query: 168 FILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFP 227 +L +++ F + L K ++ +++ N L P Sbjct: 134 DMLTYTAMDILAKAAFG----METSMLLGAQKPLSQAVKLMLEGITASRNT---LAKFLP 186 Query: 228 GTH---NKVLKNVALTRSYIREKVKEHQASLDVNN--PRDFIDCFLIKMEQEKDNQKSEF 282 G +V +++ R R+ V+ + +L P D + L E +D+ Sbjct: 187 GKRKQLREVRESIRFLRQVGRDWVQRRREALKRGEEVPADILTQILKAEEGAQDD----- 241 Query: 283 NIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDR 342 E L+ F+AG ET++ L + ++ L + PE+ A++Q E+D VIG R +D Sbjct: 242 --EGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDL 299 Query: 343 SHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFP 402 + Y V+ E R G + +T +P T ++ + D F Sbjct: 300 GRLQYLSQVLKESLRLYPPAW-GTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFE 358 Query: 403 NPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVD 462 +P F+P F G K + PFS G R C G+ A+ME+ + + +LQ + V Sbjct: 359 DPLTFNPDRF--GPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRLVP 416 Query: 463 DLK 465 + Sbjct: 417 GQR 419 >2VE3-A nrPDB Length = 444 Score = 258 bits (659), Expect = 4e-69, Method: Composition-based stats. Identities = 92/438 (21%), Positives = 170/438 (38%), Gaps = 32/438 (7%) Query: 29 LPPGPTPLPIIGNMLQ-IDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEAL 87 +PPG LP +G L ++ D K + +GP+F ++ G A+ Sbjct: 13 IPPGDFGLPWLGETLNFLNDGDFGK---KRQQQFGPIFKTRLFGKNVIFISG--ALANRF 67 Query: 88 IDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQE 147 + E+ + + P+S RI G +++ RR L R++ D Sbjct: 68 LFTKEQETFQATWPLSTRILLGPNALATQMGEIHRSRRKILYQ----AFLPRTL-DSYLP 122 Query: 148 EAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRI 207 + +V+ ++ N + +R + L + ++ ++N ++ Sbjct: 123 KMDGIVQ------------GYLEQWGKANEVIWYPQLRRMTFDVAATLFMGEKVSQNPQL 170 Query: 208 LNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCF 267 + F L I K + AL + + + +K Q P D Sbjct: 171 FPWFETYIQGLFSLPIPLPNTLFGKSQRARALLLAELEKIIKARQ-----QQPPSEEDAL 225 Query: 268 LIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEI 327 I + DN + ++ L + L AG ET ++ L LLL +H ++ +V++E Sbjct: 226 GILLAARDDNNQP-LSLPELKDQILLLLFAGHETLTSALSSFCLLLGQHSDIRERVRQEQ 284 Query: 328 DHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTI 387 + + + + MPY D V+ E+ R V G + D +F+ + PKG + Sbjct: 285 NK-LQLSQELTAETLKKMPYLDQVLQEVLRLIPPVGGG-FRELIQDCQFQGFHFPKGWLV 342 Query: 388 MALLTSVLHDDKEFPNPNIFDPGHFL-DKNGNFKKSDYFMPFSAGKRICAGEGLARMELF 446 ++ D +P+P FDP F D + +PF G R C G+ AR+E+ Sbjct: 343 SYQISQTHADPDLYPDPEKFDPERFTPDGSATHNPPFAHVPFGGGLRECLGKEFARLEMK 402 Query: 447 LFLTTILQNFNLKSVDDL 464 LF T ++Q F+ + Sbjct: 403 LFATRLIQQFDWTLLPGQ 420 >3SN5-A nrPDB Length = 491 Score = 255 bits (651), Expect = 3e-68, Method: Composition-based stats. Identities = 102/509 (20%), Positives = 178/509 (34%), Gaps = 74/509 (14%) Query: 21 RQSCRRRKLPPGPTP---LPIIGNMLQIDVKDICKSFTNFSKVYGPVFT-------VYFG 70 + S RRR+ P +P +G LQ + N + +G VFT V+F Sbjct: 4 KTSSRRRQTGEPPLENGLIPYLGCALQFGANPLEFLRAN-QRKHGHVFTCKLMGKYVHFI 62 Query: 71 MNPI----VVFHG--YEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIR 124 NP+ V+ HG ++ K + + F R P+ T+ + N K ++ Sbjct: 63 TNPLSYHKVLCHGKYFDWKKFHFALSAKAFGHRSIDPMDGNTTENI-----NDTFIKTLQ 117 Query: 125 RFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQ 184 +L +L ++E L++ P + S ++ Sbjct: 118 GHALNSL-----------------TESMMENLQRIMRPPVSSNSKTAAWVTEGMYSFCYR 160 Query: 185 KRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYI 244 F+ +LT+ R + + +NF FP + ++ T Sbjct: 161 VMFE---AGYLTIFGRDLTRRDTQKAHILNNLDNFKQFDKVFPALVAGLPIHMFRTAHNA 217 Query: 245 REKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTST 304 REK+ E ++ LI + ++ S F+ T + A T Sbjct: 218 REKLAESLRHENLQKRESI--SELISLRMFLNDTLSTFDDLEKAKTHLVVLWASQANTIP 275 Query: 305 TLRYGLLLLLKHPEVTAKVQEEIDHVI----------GRHRSPCMQDRSHMPYTDAVVHE 354 + L ++++PE EE+ + G + + +P D+++ E Sbjct: 276 ATFWSLFQMIRNPEAMKAATEEVKRTLENAGQKVSLEGNPICLSQAELNDLPVLDSIIKE 335 Query: 355 IQRYSDLVPTGVPHAVTTDTKF----RNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPG 410 R S + D +Y I K I + D + +P+P F Sbjct: 336 SLRLSS--ASLNIRTAKEDFTLHLEDGSYNIRKDDIIALYPQLMHLDPEIYPDPLTFKYD 393 Query: 411 HFLDKNGNFKKS---------DYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSV 461 +LD+NG K + Y+MPF +G IC G A E+ FL +L F L+ + Sbjct: 394 RYLDENGKTKTTFYCNGLKLKYYYMPFGSGATICPGRLFAIHEIKQFLILMLSYFELELI 453 Query: 462 DDL---KNLNTTAVTKGIVSLPPSYQICF 487 + L+ + GI LPP I F Sbjct: 454 EGQAKCPPLDQSRAGLGI--LPPLNDIEF 480 >3EL3-A nrPDB Length = 467 Score = 246 bits (627), Expect = 2e-65, Method: Composition-based stats. Identities = 91/446 (20%), Positives = 165/446 (36%), Gaps = 24/446 (5%) Query: 35 PLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEF 94 +P++G+ ++ +F + + +G V + G + E + AL N + Sbjct: 30 GVPLLGHGWRLARD--PLAFMSQLRDHGDVVRIKLGPKTVYAVTNPE-LTGALALNPDYH 86 Query: 95 SGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVE 154 + + G+ ++NG + RR R + ++EEAH L E Sbjct: 87 IAGPLWESLEGLLGKEGVATANGPLHRRQRRTIQPAFRLDAIPAYG--PIMEEEAHALTE 144 Query: 155 ELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQ 214 + K C + Q + ++ + L F +R + P Sbjct: 145 RWQPGKTVDATSESFRVAVRVAARCLLRGQYMDERAERLCVALATVFRGMYRRMVVPLG- 203 Query: 215 VCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQE 274 PL P + + +A + E + E +AS P D + L + Sbjct: 204 -----PLYRLPLPA-NRRFNDALADLHLLVDEIIAERRAS--GQKPDDLLTALL----EA 251 Query: 275 KDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRH 334 KD+ + + V + G+ET ++T+ + L L HPE ++++E++ V G Sbjct: 252 KDDNGDPIGEQEIHDQVVAILTPGSETIASTIMWLLQALADHPEHADRIRDEVEAVTG-G 310 Query: 335 RSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSV 394 R +D + +T V+ E R V AV ++ Y IP G I+ ++ Sbjct: 311 RPVAFEDVRKLRHTGNVIVEAMRLRPAVWVLTRRAVAE-SELGGYRIPAGADIIYSPYAI 369 Query: 395 LHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQ 454 D K + + FDP +L + PFSAGKR C + + +L L + Sbjct: 370 QRDPKSYDDNLEFDPDRWLPERAANVPKYAMKPFSAGKRKCPSDHFSMAQLTLITAALAT 429 Query: 455 NFNLKSVDDLKNLNTTAVTKGIVSLP 480 + + V + AV GI P Sbjct: 430 KYRFEQVAG----SNDAVRVGITLRP 451 >6AYB-A nrPDB Length = 466 Score = 245 bits (624), Expect = 5e-65, Method: Composition-based stats. Identities = 87/458 (18%), Positives = 176/458 (38%), Gaps = 14/458 (3%) Query: 19 LWRQSCRRRKLPPG-PTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVF 77 + +++ + KLPP P +P +G+ + K+ + + SK YG VFT + Sbjct: 1 MAKKTSSKGKLPPRVPNLIPYVGSFVSF-AKNPVQFIIDNSKKYGDVFTATILGKEMTFL 59 Query: 78 HGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMG 137 + + + E S R + R G G++ + + + + Sbjct: 60 NHPKILDTFFKATDNELSLR-DVYRFMRPVFGTGVVYDADSTERMMEQVKFVSSGLTTAR 118 Query: 138 KRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTL 197 R D ++E V+EL C + + R ++N L Sbjct: 119 FRVFVDIFEDEIAHKVKELGPEGTVDVAELMADLIIFTASRCLLGDEVRQYLSEKNLGKL 178 Query: 198 MKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDV 257 ++ SP + P V + RE+ K+H L Sbjct: 179 YHDIDDGI----SPLSFFYPSLPAPKRD--KARKAVGEIFQELLDKRREEHKKHPERLLD 232 Query: 258 NNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHP 317 + D +D L ++ KD Q E + +G + AG T+S T + L+ ++ + Sbjct: 233 ESKMDVVDHLL--TQKYKDGQ--ELTDVHRIGILIAGLFAGQHTSSITSSWTLMNVISNK 288 Query: 318 EVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFR 377 +V KV++E + ++G + M Y +A + E R + + + Sbjct: 289 KVLEKVRKEQEEIMGSDKVLDYDKVMKMDYLEACMKEALRMYPPL-IMIMRMARKPRECE 347 Query: 378 NYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAG 437 Y+IPKG ++ + + NP++FDP ++ + K +PF AG+ C G Sbjct: 348 QYIIPKGNILVVSPSVAGRCTDTYTNPDVFDPERLTERKEHEKFKYGAVPFGAGRHKCIG 407 Query: 438 EGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKG 475 E A +++ ++ +L+ F+++ + + + + T++ G Sbjct: 408 ENFALLQVKSIISILLRYFDMEYIGKIPDPSYTSLVVG 445 >2VZM-A nrPDB Length = 436 Score = 231 bits (590), Expect = 4e-61, Method: Composition-based stats. Identities = 87/475 (18%), Positives = 147/475 (30%), Gaps = 80/475 (16%) Query: 19 LWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFG-MNPIVVF 77 + R PP +G + Q D ++ GP V N + + Sbjct: 21 MRRTQQGTTASPPVLD----LGALGQDFAADPYPTYARLRAE-GPAHRVRTPEGNEVWLV 75 Query: 78 HGYEAVKEALIDN--GEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFG 135 GY+ + L D +++ ++ S+ R +R+ R F Sbjct: 76 VGYDRARAVLADPRFSKDWRNSTTPLTEAEAALNHNMLESDPPRHTRLRKLVA---REFT 132 Query: 136 MGKRSI-EDRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNVICSVVFQKRFDYKDQN 193 M + + RVQE LV+ + D L P VI ++ D Sbjct: 133 MRRVELLRPRVQEIVDGLVDAMLAAPDGRADLMESLAWPLPITVISELLGVPEPDRA--- 189 Query: 194 FLTLMKRFNENFRILNSPWIQVCNNFPLLID--CFPGTHNKVLKNVALTRSYIREKVKEH 251 F + D FP + +A Y+ + Sbjct: 190 ------------------------AFRVWTDAFVFPDDPAQAQTAMAEMSGYLSRLIDSK 225 Query: 252 QASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLL 311 + + L + + D S E L+G L VAG ETT + G+ Sbjct: 226 R--------GQDGEDLLSALVRTSDEDGSRLTSEELLGMAHILLVAGHETTVNLIANGMY 277 Query: 312 LLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVT 371 LL HP+ A ++ + M D V E+ RY V + Sbjct: 278 ALLSHPDQLAALRAD------------------MTLLDGAVEEMLRYEGPVESATYRFPV 319 Query: 372 TDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAG 431 +IP G T++ +L + FP+P+ FD + + F G Sbjct: 320 EPVDLDGTVIPAGDTVLVVLADAHRTPERFPDPHRFDIRR---------DTAGHLAFGHG 370 Query: 432 KRICAGEGLARMELFLFLTTILQN---FNLKSVDDLKNLNTTAVTKGIVSLPPSY 483 C G LAR+E + + +L+ L + +G+ +LP + Sbjct: 371 IHFCIGAPLARLEARIAVRALLERCPDLALDVSPGELVWYPNPMIRGLKALPIRW 425 >4MM0-A nrPDB Length = 399 Score = 229 bits (584), Expect = 2e-60, Method: Composition-based stats. Identities = 75/420 (17%), Positives = 142/420 (33%), Gaps = 73/420 (17%) Query: 72 NPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGL--GIISSNGKRWKEIRRFSLT 129 +P + YE V+ L D FS R + P + R+T+ +++++ +RR Sbjct: 45 DPGFLVTRYEDVRFVLSD--PRFSVRQDLPGAPRLTEMTFESVMTTDPPVHTRLRRL--- 99 Query: 130 TLRNFGMGK-RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNVICSVVFQKRF 187 R+F + + R++E A L++E+ K K +P D L P VIC ++ Sbjct: 100 LSRDFTARRIERMRPRLEEIAEGLLDEMEK-KGAPADIVESLAVPFPITVICELLGVPMV 158 Query: 188 DYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREK 247 D F D +++ R + Sbjct: 159 D---------------------------VARFRGWADTMVSLTGYSMEDWTAARDALESY 191 Query: 248 VKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLR 307 + A+ N D + + ++ +E ++ L +AG E S L Sbjct: 192 LDGLVAAKRENPGSDLLSALVATAAED-----NELTDHDVRSLSLILLLAGYEPASNQLG 246 Query: 308 YGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVP 367 +L LL+ P+ A+++ + + V E+ RY+ + Sbjct: 247 SSVLTLLRFPDRLAELRRDPG------------------LLPSAVEELMRYAPAGDGALF 288 Query: 368 HAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMP 427 D + IP + ++A + D + F +P + Sbjct: 289 RVTLEDVTIGDTHIPANSAVLASTQAANWDPRRFDDPTGLRLDR---------PDNQHTA 339 Query: 428 FSAGKRICAGEGLARMELFLFLTTILQNF-NLKSVDDLKNLN---TTAVTKGIVSLPPSY 483 G C G LAR+EL + + +L+ F L D L ++ G +P ++ Sbjct: 340 LGHGIHFCLGAALARVELQVAIGALLRRFPRLALATDESGLRWSSPGSMLSGFAEIPVTW 399 >5CJE-A nrPDB Length = 393 Score = 229 bits (584), Expect = 2e-60, Method: Composition-based stats. Identities = 86/452 (19%), Positives = 149/452 (32%), Gaps = 72/452 (15%) Query: 39 IGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIV---VFHGYEAVKEALIDNGEEFS 95 +G +D + + GPV V + G+E + AL D Sbjct: 7 LGEYGARFTEDPYPVYAELRER-GPVHWVRTPPPEAFEGWLVVGHEEARAALADPRLSKD 65 Query: 96 G-RGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGK-RSIEDRVQEEAHCLV 153 G + G ++ + +R R F M + ++ R+QE L+ Sbjct: 66 GTKKGLTSLDVELMGPYLLVVDPPEHTRLRSLVA---RAFTMRRVEALRPRIQEITDGLL 122 Query: 154 EELRKTKASPCDPTFILGCA-PCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPW 212 +E+ D P VIC ++ D FR L++ Sbjct: 123 DEMLPRGR--ADLVDSFAYPLPITVICELLGVPDIDRV-------------TFRALSNEI 167 Query: 213 IQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKME 272 + P + L +Y+ E + + +++ P D + LI+ Sbjct: 168 VA------------PTGGDAELAAYERLAAYLDELIDDKRST----APADDLLGDLIRTR 211 Query: 273 QEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIG 332 E D+ + E L L VAG ETT + G+ LL HP+ A ++ + Sbjct: 212 AEDDD---RLSGEELRAMAFILLVAGHETTVNLITNGVHTLLTHPDQLAALRAD------ 262 Query: 333 RHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLT 392 M D V E+ R+ V T + I +G +M L Sbjct: 263 ------------MTLLDGAVEEVLRFEGPVETATYRYAAESMEIGGTAIAEGDPVMIGLD 310 Query: 393 SVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTI 452 + D P+P++FD + + F G C G LAR+E + L ++ Sbjct: 311 AAGRDPARHPDPHVFDI---------HRAPQGHLAFGHGIHYCLGAPLARLEARVALRSL 361 Query: 453 LQNF-NLKSVDDLKNLNTTAVTKGIVSLPPSY 483 L+ +L + +G+ LP + Sbjct: 362 LERCPDLALDGPPGARPPGMLIRGVRRLPVRW 393 >4OQS-A nrPDB Length = 433 Score = 229 bits (583), Expect = 3e-60, Method: Composition-based stats. Identities = 87/427 (20%), Positives = 138/427 (32%), Gaps = 89/427 (20%) Query: 76 VFHGYEAVKEALIDNGEEFSGRGNS--PISQRITKGLG---------IISSNGKRWKEIR 124 + + A + +ID FS R P+ I + G I+ + R Sbjct: 49 LVTSHAAARTVMID--PRFSNRPEHKHPVFSVIPRPGGATKAPAPGWFINMDAPEHTRYR 106 Query: 125 RFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNVICSVVF 183 R ++ + + +E R+ + ++ + K P D P VIC ++ Sbjct: 107 RMLISQFTVRRI--KELEPRIVQITEDHLDAMAK-AGPPVDLVQAFALPVPSLVICELLG 163 Query: 184 QKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSY 243 Y D F + T ++V + Y Sbjct: 164 ---VSYADHAFFQEQTTIMASVD---------------------KTQDEVTTALGKLTRY 199 Query: 244 IREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTS 303 I E V + S P+D + LI ++ E L L VAG ETT+ Sbjct: 200 IAELVATKRLS-----PKDDLLGSLI--------TDTDLTDEELTNIALLLLVAGHETTA 246 Query: 304 TTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVP 363 L G LL+HPE A + V E+ RY +V Sbjct: 247 NMLGLGTFALLQHPEQIAALDS-----------------------PDAVEELLRYLSIVH 283 Query: 364 TGVP-HAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKS 422 G P A D + +I KG T+ L +V D K F P+I + Sbjct: 284 LGTPNRAALEDVELEGQMIRKGDTVAIGLPAVNRDPKVFDEPDILQLDRVDARK------ 337 Query: 423 DYFMPFSAGKRICAGEGLARMELFLFLTTILQNF---NLKSVDDLKNLNTTAVTKGIVSL 479 F G C G+ LAR+E+ + T + F L + L + G+ +L Sbjct: 338 --HAAFGGGIHQCLGQQLARVEMRIGFTRLFARFPSLRLAVPAEEIKLREKSAAYGVWAL 395 Query: 480 PPSYQIC 486 P ++ Sbjct: 396 PVAWDAR 402 >4OQR-A nrPDB Length = 457 Score = 226 bits (577), Expect = 1e-59, Method: Composition-based stats. Identities = 90/435 (20%), Positives = 141/435 (32%), Gaps = 89/435 (20%) Query: 68 YFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNS--PISQRITKGLGIISSNGKRW----- 120 + G + + A + +ID FS R P+ I + G + W Sbjct: 84 HIGW----LVTSHAAARTVMID--PRFSNRPEHKHPVFSVIPRPGGATKAPAPGWFTNMD 137 Query: 121 -KEIRRFSLTTLRNFGMGK-RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNV 177 E R+ + F + + + +E R+ ++ + K P D P V Sbjct: 138 APEHTRYRRMLISQFTVRRIKELEPRIVRITEDHLDAMAK-AGPPVDLVQAFALPVPSLV 196 Query: 178 ICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNV 237 IC ++ Y D F + T ++V + Sbjct: 197 ICELLG---VSYADHAFFQEQTTIMVSVD---------------------KTQDEVTTAL 232 Query: 238 ALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVA 297 YI E V + S P+D + LI ++ E L L VA Sbjct: 233 GKLTRYIAELVATKRLS-----PKDDLLGSLI--------TDTDLTDEELTNIALILLVA 279 Query: 298 GTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQR 357 G ETT+ L G LL+HPE A + V E+ R Sbjct: 280 GHETTANMLGLGTFALLQHPEQIANLDS-----------------------PDAVEELLR 316 Query: 358 YSDLVPTGVP-HAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKN 416 Y +V G P A D + +I KG T+ L +V D K F P+I + Sbjct: 317 YLSIVHLGTPNRAALEDVELEGQMIRKGDTVAIGLPAVNRDPKVFDEPDILQLDRVDARK 376 Query: 417 GNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF---NLKSVDDLKNLNTTAVT 473 F G C G+ LAR+E+ + T + F L + L + Sbjct: 377 --------HAAFGGGIHQCLGQQLARVEMRIGFTRLFARFPSLRLAVPAEEIKLREKSAA 428 Query: 474 KGIVSLPPSYQICFI 488 G+ +LP ++ I Sbjct: 429 YGVWALPVAWDALGI 443 >4UBS-A nrPDB Length = 393 Score = 226 bits (575), Expect = 2e-59, Method: Composition-based stats. Identities = 78/429 (18%), Positives = 147/429 (34%), Gaps = 78/429 (18%) Query: 66 TVYFGMNPIVVFHGYEAVKEALIDNGEEFSGR--GNSPISQRITKGL-----GIISSNGK 118 ++Y G + V G+ A + L D S R P + + + ++ + Sbjct: 32 SLYDG-RSVWVVTGHAAARALLSDQRLS-SDRTLPRFPATTERFEAVRTRRVALLGVDDP 89 Query: 119 RWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNV 177 + RR + + ++ R+QE L++ + + P + P V Sbjct: 90 EHRTQRRMLVPSFTL--KRAAALRPRIQETVDGLLDAMEA-QGPPAELVSAFALPLPSMV 146 Query: 178 ICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNV 237 IC+++ Y D +F R R+L P I + +D Sbjct: 147 ICALLG---VPYADHDFFESQSR-----RLLRGPGIAEVQDARAQLD------------- 185 Query: 238 ALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVA 297 Y+ + + P D + LI+ + + + LV L +A Sbjct: 186 ----DYLYALIDRKRK-----EPGDGLLDDLIQEQL----NRGTVDRAELVSLATLLLIA 232 Query: 298 GTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQR 357 G ETT+ + G LL+HPE A+++ E A V E+ R Sbjct: 233 GHETTANMISLGTFTLLRHPEQLAELRAEPG------------------LMPAAVEELLR 274 Query: 358 YSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNG 417 + + G+ T D + I ++ + + D F P+ D Sbjct: 275 FLSIAD-GLLRVATEDIEVAGTTIRADEGVVFATSVINRDAAGFAEPDALD--------- 324 Query: 418 NFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQN---FNLKSVDDLKNLNTTAVTK 474 + + + + F G C G+ LAR E+ + L T+ + L + D + Sbjct: 325 WHRSARHHVAFGFGIHQCLGQNLARAEMEIALGTLFERLPGLRLAAPADEIPFKPGDTIQ 384 Query: 475 GIVSLPPSY 483 G++ LP ++ Sbjct: 385 GMLELPVTW 393 >5Y1I-A nrPDB Length = 403 Score = 225 bits (574), Expect = 3e-59, Method: Composition-based stats. Identities = 87/431 (20%), Positives = 145/431 (33%), Gaps = 77/431 (17%) Query: 66 TVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIIS--------SNG 117 ++ G P VV + + L D S G I+ +S + Sbjct: 37 RIWDGSTPWVV-TRHADQRALLSD--PRVSHDGLRDGYPHISADFKFLSMAQPSFAGQDD 93 Query: 118 KRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCN 176 IRR TL ++ +Q+ L++ + P D L P Sbjct: 94 PEHGRIRRMV--TLPFTARRIEAMRPAIQKITDELIDGMLAGP-KPVDLVEALALPVPVR 150 Query: 177 VICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKN 236 VIC ++ Y+D+ FL Q NN + D G K Sbjct: 151 VICEMLG---VPYEDREFL------------------QQNNNAMIYRDTAQGDAQKAAIA 189 Query: 237 VALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFV 296 A+ Y++E V + + D + +++E E ++ G L Sbjct: 190 QAM---YLKELV----GTKLGDRGDDILSDLAVQVEA------GEITQDDAAGIGMMLLG 236 Query: 297 AGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQ 356 AG ETT+ + G L LL++PE A+V++ D + + V E+ Sbjct: 237 AGHETTANMIALGTLALLENPEQLAEVRDSDDPKVIVN----------------TVEELL 280 Query: 357 RYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPN-PNIFDPGHFLDK 415 RY + V D + +I G I+ L + D +P P+ D Sbjct: 281 RYLTIAQDTVRRIAAEDIEIGGVVIKAGEGIVFPLNAANWDPDLYPEAPDRLDIHRA--- 337 Query: 416 NGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQN---FNLKSVDDLKNLNTTAV 472 + + F G C G LAR+EL + +T+L+ L D + Sbjct: 338 -----NARRHLAFGYGVHQCLGATLARVELQIVYSTLLRRIPTLALAGTLDEIPFKHDQI 392 Query: 473 TKGIVSLPPSY 483 G+ LP ++ Sbjct: 393 AHGVYELPVTW 403 >3EJB-B nrPDB Length = 404 Score = 225 bits (574), Expect = 3e-59, Method: Composition-based stats. Identities = 83/446 (18%), Positives = 146/446 (32%), Gaps = 69/446 (15%) Query: 48 KDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRIT 107 K+ + V+ P++ F P GYE + A I F R P S Sbjct: 13 KNPYSFYDTLRAVH-PIYKGSFLKYPGWYVTGYE--ETAAILKDARFKVRTPLPESSTKY 69 Query: 108 KGLG------IISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKA 161 + L ++ N + +R + S + + E H L+++++ K Sbjct: 70 QDLSHVQNQMMLFQNQPDHRRLRTLASGAFTPRT--TESYQPYIIETVHHLLDQVQGKKK 127 Query: 162 SPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPL 221 F A VI +++ +D+ L W Sbjct: 128 MEVISDFAFPLASF-VIANIIG---VPEEDREQLKE--------------WAASLIQTID 169 Query: 222 LIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSE 281 + V +Y +E +++ + +P+ + L+ K +K + Sbjct: 170 FTRSRKALTEGNIMAVQAM-AYFKELIQKRKR-----HPQQDMISMLL-----KGREKDK 218 Query: 282 FNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQD 341 E T L +AG ETT + +L LL+HPE K++E D + Sbjct: 219 LTEEEAASTCILLAIAGHETTVNLISNSVLCLLQHPEQLLKLRENPDLI----------- 267 Query: 342 RSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEF 401 V E RY + D I +G + LL + D F Sbjct: 268 -------GTAVEECLRYESPTQ-MTARVASEDIDICGVTIRQGEQVYLLLGAANRDPSIF 319 Query: 402 PNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF-NLKS 460 NP++FD + + F G +C G LAR+E + + T+LQ +L Sbjct: 320 TNPDVFDITR---------SPNPHLSFGHGHHVCLGSSLARLEAQIAINTLLQRMPSLNL 370 Query: 461 VDDLKNLNTTAVTKGIVSLPPSYQIC 486 D + + LP +++ Sbjct: 371 ADFEWRYRPLFGFRALEELPVTFEAS 396 >5JLC-A nrPDB Length = 515 Score = 225 bits (573), Expect = 4e-59, Method: Composition-based stats. Identities = 89/506 (17%), Positives = 183/506 (36%), Gaps = 57/506 (11%) Query: 5 VVLVLCLSFMLLFSLWRQSCRRRKLPPGPTPL-PIIGNMLQIDVKDICKSFTNFSKVYGP 63 + V +++ LL+SL + PP P +G+ + K + F + K YG Sbjct: 19 LPFVYTITWQLLYSLRKDR------PPLVFYWIPWVGSAIPYGTK-PYEFFEDCQKKYGD 71 Query: 64 VFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEI 123 +F+ + V+ G + + + S G G+I Sbjct: 72 IFSFMLLGRIMTVYLGPKGHEFIFNAKLADVSAEAAYSHLTTPVFGKGVIYDCP----NH 127 Query: 124 RRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCD-----PTFILGCAPCNVI 178 R + K + V A + + R +K + ++ P I Sbjct: 128 RLMEQKKFVKGALTKEAFVRYVPLIAEEIYKYFRNSKNFKINENNSGIVDVMVSQPEMTI 187 Query: 179 C----SVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVL 234 S++ ++ D D +F L ++ F + NF + Sbjct: 188 FTASRSLLGKEMRDKLDTDFAYLYSDLDKGFTPI---------NFVFPNLPLEHYRKRDH 238 Query: 235 KNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADL 294 A++ +Y+ +KE + D+ N RD ID L+K KD ++ + + + + Sbjct: 239 AQQAISGTYM-SLIKERREKNDIQN-RDLIDE-LMKNSTYKDG--TKMTDQEIANLLIGV 293 Query: 295 FVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRH-RSPCMQDRSHMPYTDAVVH 353 + G T++ T + LL L + P+V ++ +E V+ + D +MP + ++ Sbjct: 294 LMGGQHTSAATSAWCLLHLAERPDVQEELYQEQMRVLNNDTKELTYDDLQNMPLLNQMIK 353 Query: 354 EIQRYSDLVPTGVPHAVTTDTKFRN--YLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGH 411 E R + + + V D N Y++P+ ++ ++ FP PN F+ Sbjct: 354 ETLRLHHPLHS-LFRKVMRDVAIPNTSYVVPRDYHVLVSPGYTHLQEEFFPKPNEFNIHR 412 Query: 412 FLDKNGNFKK-----------------SDYFMPFSAGKRICAGEGLARMELFLFLTTILQ 454 + + S ++PF G+ C GE A +L + ++ ++ Sbjct: 413 WDGDAASSSAAGGDEVDYGFGAISKGVSSPYLPFGGGRHRCIGELFAYCQLGVLMSIFIR 472 Query: 455 NFNLKSVDDLKNLNTTAVTKGIVSLP 480 + + + + + T +V+LP Sbjct: 473 TMKWRYPTEGETVPPSDFTS-MVTLP 497 >2WX2-A nrPDB Length = 473 Score = 223 bits (569), Expect = 1e-58, Method: Composition-based stats. Identities = 85/453 (18%), Positives = 166/453 (36%), Gaps = 29/453 (6%) Query: 30 PPGPTPLPIIGNMLQIDVKDICKSFTNFSK--VYGPVFTVYFGMNPIVVFHGYEAVKEAL 87 P P +P +G+++Q K+ + + G VFT+ G + + Sbjct: 19 PVYPVTVPFLGHIVQFG-KNPLEFMQRCKRDLKSG-VFTISIGGQRVTIVGDPHEHSRFF 76 Query: 88 IDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQE 147 E S R I + ++ R +E F L ++ +Q Sbjct: 77 SPRNEILSPREVYTIMTPVFGEGVAYAAPYPRMREQLNFLAEELTIAKF--QNFVPAIQH 134 Query: 148 EAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRI 207 E + E K + G N C +F +D + F + Sbjct: 135 EVRKFMAENWKEDEGVINLLEDCGAMIINTACQCLFG-----EDLRKRLNARHFAQLLSK 189 Query: 208 LNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKV--KEHQASLDVNNPRDFID 265 + S I P L+ + + A + + E + +E + + NN D + Sbjct: 190 MESSLIPAAVFMPWLLRLPLPQSARCREARAELQKILGEIIVAREKEEASKDNNTSDLLG 249 Query: 266 CFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLK--HPEVTAKV 323 L + ++ + ++ + G + AG T++ T + +L L+ + + K+ Sbjct: 250 GLLKAVYRDG----TRMSLHEVCGMIVAAMFAGQHTSTITTSWSMLHLMHPKNKKWLDKL 305 Query: 324 QEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPK 383 +EID + + D MP+ + V E R + V V + K +Y++PK Sbjct: 306 HKEIDEFPAQLNYDNVMD--EMPFAERCVRESIRRDPPL-LMVMRMVKAEVKVGSYVVPK 362 Query: 384 GTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARM 443 G I HD++ FPNP ++DP + K F+ F AG C G+ A + Sbjct: 363 GDIIACSPLLSHHDEEAFPNPRLWDPER------DEKVDGAFIGFGAGVHKCIGQKFALL 416 Query: 444 ELFLFLTTILQNFNLKSV-DDLKNLNTTAVTKG 475 ++ L T + ++ + + D++ + + + G Sbjct: 417 QVKTILATAFREYDFQLLRDEVPDPDYHTMVVG 449 >4WMZ-A nrPDB Length = 539 Score = 223 bits (568), Expect = 1e-58, Method: Composition-based stats. Identities = 86/484 (17%), Positives = 171/484 (35%), Gaps = 47/484 (9%) Query: 24 CRRRKLPPGPTPL-PIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEA 82 R+ PP P +G+ + +K + F K YG +F+ + V+ G + Sbjct: 50 SLRKDRPPLVFYWIPWVGSAVVYGMK-PYEFFEECQKKYGDIFSFVLLGRVMTVYLGPKG 108 Query: 83 VKEALIDNGEEFSGRGNSPISQRITKGLGIISSNG-KRWKEIRRFSLTTLRNFGMGKRSI 141 + + S G G+I R E ++F L +S Sbjct: 109 HEFVFNAKLADVSAEAAYAHLTTPVFGKGVIYDCPNSRLMEQKKFVKGALTKEAF--KSY 166 Query: 142 EDRVQEEAHCLVE---ELRKTKASPCDPTFILGCAPCNVIC---SVVFQKRFDYKDQNFL 195 + EE + R + + ++ + S++ ++ D +F Sbjct: 167 VPLIAEEVYKYFRDSKNFRLNERTTGTIDVMVTQPEMTIFTASRSLLGKEMRAKLDTDFA 226 Query: 196 TLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASL 255 L ++ F + NF + A++ +Y+ +KE + + Sbjct: 227 YLYSDLDKGFTPI---------NFVFPNLPLEHYRKRDHAQKAISGTYM-SLIKERRKNN 276 Query: 256 DVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLK 315 D+ + RD ID L+K KD K + + + + + G T++ T + LL L + Sbjct: 277 DIQD-RDLIDS-LMKNSTYKDGVK--MTDQEIANLLIGVLMGGQHTSAATSAWILLHLAE 332 Query: 316 HPEVTAKVQEEIDHVI-GRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDT 374 P+V ++ EE V+ G + MP + + E R + + + V D Sbjct: 333 RPDVQQELYEEQMRVLDGGKKELTYDLLQEMPLLNQTIKETLRMHHPLHS-LFRKVMKDM 391 Query: 375 KFRN--YLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNF------------- 419 N Y+IP G ++ D+ FPN + F+ + + + + Sbjct: 392 HVPNTSYVIPAGYHVLVSPGYTHLRDEYFPNAHQFNIHRWNNDSASSYSVGEEVDYGFGA 451 Query: 420 ---KKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGI 476 S ++PF G+ C GE A +L + ++ ++ + + + Sbjct: 452 ISKGVSSPYLPFGGGRHRCIGEHFAYCQLGVLMSIFIRTLKWHYPEGKTVPPPDFTS--M 509 Query: 477 VSLP 480 V+LP Sbjct: 510 VTLP 513 >5FSA-A nrPDB Length = 490 Score = 221 bits (564), Expect = 4e-58, Method: Composition-based stats. Identities = 94/487 (19%), Positives = 173/487 (35%), Gaps = 52/487 (10%) Query: 27 RKLPPGPTPL-PIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKE 85 +K PP P G+ + + F + + YG VF+ + V+ G + + Sbjct: 3 KKTPPLVFYWIPWFGSAASYGQQ-PYEFFESCRQKYGDVFSFMLLGKIMTVYLGPKGHEF 61 Query: 86 ALIDNGEEFSGRGNSPISQRITKGLGIISSNG-KRWKEIRRFSLTTLRNFGMGKRSIEDR 144 + S G G+I R E ++F+ L KR + Sbjct: 62 VFNAKLSDVSAEEAYKHLTTPVFGTGVIYDCPNSRLMEQKKFAKFALTTDSF-KRYVPKI 120 Query: 145 VQEEAHCLV-EELRKTKASPCDPTFILGCAPCNVI---CSVVFQKRFDY-KDQNFLTLMK 199 +E + V +E K K ++ P I +F D++F L Sbjct: 121 REEILNYFVTDESFKLKEKTHGVANVMKTQPEITIFTASRSLFGDEMRRIFDRSFAQLYS 180 Query: 200 RFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNN 259 ++ F + NF P + ++ +Y++E +K + D++ Sbjct: 181 DLDKGFTPI---------NFVFPNLPLPHYWRRDAAQKKISATYMKE-IKLRRERGDIDP 230 Query: 260 PRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEV 319 RD ID LI KD K + + + + + G T+++T + LL L + P + Sbjct: 231 NRDLIDSLLIH-STYKDGVK--MTDQEIANLLIGILMGGQHTSASTSAWFLLHLGEKPHL 287 Query: 320 TAKVQEEIDHVI----GRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTK 375 + +E+ ++ G +D +P + + E R + + + VT + Sbjct: 288 QDVIYQEVVELLKEKGGDLNDLTYEDLQKLPSVNNTIKETLRMHMPLHS-IFRKVTNPLR 346 Query: 376 FR--NYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKK------------ 421 NY++PKG ++ ++ F NP FDP + Sbjct: 347 IPETNYIVPKGHYVLVSPGYAHTSERYFDNPEDFDPTRWDTAAAKANSVSFNSSDEVDYG 406 Query: 422 --------SDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVT 473 S ++PF G+ C GE A ++L LTT + N ++D K + Sbjct: 407 FGKVSKGVSSPYLPFGGGRHRCIGEQFAYVQLGTILTTFVYNLRW-TIDGYKVPDPD--Y 463 Query: 474 KGIVSLP 480 +V LP Sbjct: 464 SSMVVLP 470 >5VWS-A nrPDB Length = 393 Score = 221 bits (564), Expect = 4e-58, Method: Composition-based stats. Identities = 82/422 (19%), Positives = 146/422 (34%), Gaps = 64/422 (15%) Query: 63 PVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKE 122 PV+ FG I Y+ V++ L D S R + + GI + + Sbjct: 32 PVWRDQFG---IYHVFRYDDVRQILGDYQTFSSDRTRLMPTAQGFGKGGITMIDPPEHRH 88 Query: 123 IRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNVICSV 181 RR + ++E R+++ A L++EL D P VI + Sbjct: 89 QRRLITHAFTPQSIS--AMEPRIRQIADHLLDEL---PGPEFDLVEHFAYPLPVIVIAEL 143 Query: 182 VFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTR 241 + D++ R+++ + ++ + VA Sbjct: 144 LG---VPPGDRHLFRTWSD-----RLMSLQVENYADP-------------ELARTVAAAM 182 Query: 242 SYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTET 301 + + + ++EH S +PRD + L++ E E ++E +V T + L +AG T Sbjct: 183 TEMNDYLREHCRSRR-THPRDDLLTRLVQAEVEGK----RLDLEEVVNTASLLLLAGHLT 237 Query: 302 TSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDL 361 T+ + +L L HPE V+ + + A + E R Sbjct: 238 TTVLIGNTMLCLWDHPEAEKAVRADPSLI------------------PAALEESLRLRSP 279 Query: 362 VPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKK 421 T D IP +MA + S HDD+ FP+P FD ++ Sbjct: 280 FLQA-GRVTTRDVTIAGETIPANRFVMAWILSANHDDRRFPDPERFD---------LHRQ 329 Query: 422 SDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLN-TTAVTKGIVSLP 480 + + F G C G L R+E + L +L F + ++ + G +P Sbjct: 330 TTGHIAFGHGVHFCLGAQLGRLEGRIALERLLGRFTEIHPWPREGISFYQSAIFGASRMP 389 Query: 481 PS 482 Sbjct: 390 VR 391 >2Z36-A nrPDB Length = 413 Score = 220 bits (560), Expect = 1e-57, Method: Composition-based stats. Identities = 75/420 (17%), Positives = 135/420 (32%), Gaps = 76/420 (18%) Query: 77 FHGYEAVKEALID----NGEEFSGRGNSPIS-----QRITKGLGIISSNGKRWKEIRRFS 127 G+E + L D + + G + Q ++ ++ +G RR Sbjct: 51 VSGHEEARAVLADGRFSSDKRKDGFPLFTLDAATLQQLRSQPPLMLGMDGAEHSAARRPV 110 Query: 128 LTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNVICSVVFQKR 186 + + ++ R+Q+ ++++ T P D L P VIC ++ Sbjct: 111 IGEFTVKRLA--ALRPRIQDIVDHFIDDMLATDQRPVDLVQALSLPVPSLVICELLG--- 165 Query: 187 FDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIRE 246 Y D +F + + + A R+YI + Sbjct: 166 VPYTDHDFFQSRTTMMVSRTSM----------------------EDRRRAFAELRAYIDD 203 Query: 247 KVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTL 306 + + P D + I ++ Q+ + LV L AG ETT+ + Sbjct: 204 LITRK-----ESEPGDDLFSRQIARQR----QEGTLDHAGLVSLAFLLLTAGHETTANMI 254 Query: 307 RYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGV 366 G++ LL HPE V+ T V E+ RY + Sbjct: 255 SLGVVGLLSHPEQLTVVKANPGR------------------TPMAVEELLRYFTIADGVT 296 Query: 367 PHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFM 426 T D + I G ++ + S D F +P + D + + + Sbjct: 297 SRLATEDVEIGGVSIKAGEGVIVSMLSANWDPAVFKDPAVLDVER---------GARHHL 347 Query: 427 PFSAGKRICAGEGLARMELFLFLTTILQN---FNLKSVDDLKNLNTTAVTKGIVSLPPSY 483 F G C G+ LARMEL + T+ + L + +V G+ LP ++ Sbjct: 348 AFGFGPHQCLGQNLARMELQIVFDTLFRRIPSLRLAVPMEDVPFKGDSVIYGVHELPVTW 407 >6C94-A nrPDB Length = 497 Score = 219 bits (559), Expect = 2e-57, Method: Composition-based stats. Identities = 78/445 (17%), Positives = 159/445 (35%), Gaps = 19/445 (4%) Query: 31 PGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDN 90 PGP + G+ L+I +++ + ++ G + +A+ Sbjct: 25 PGPPTHWLFGHALEIQKTGSLDKVVTWTQQFPYAHPLWVGQFIGFLNIYEPDYAKAVYSR 84 Query: 91 GEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAH 150 G+ + + G G++ +G +W + R+ + + + Sbjct: 85 GDPKA--PDVYDFFLQWIGKGLLVLDGPKWFQHRKLLTPGFHYDVL--KPYVAIFADSTR 140 Query: 151 CLVEELRK--TKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRIL 208 ++E+ K + D +G + + F K D + L Sbjct: 141 IMLEKWEKKACEGKSFDIFSDVGHMALDTLMKCTFGK----GDSGLNHRDSSYYVAVSEL 196 Query: 209 NSPWIQVCNNFPLLIDC---FPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFI- 264 Q ++F D + L+ + +++ +A+L R+ I Sbjct: 197 TLLMQQRIDSFQYHNDFIYWLTPHGRRFLRACRAAHDHTDRVIRQRKAALQDEKEREKIQ 256 Query: 265 ----DCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVT 320 FL + + + + +L V G +TT++ + + L + +PE Sbjct: 257 NRRHLDFLDILLDVRGESGVQLSDTDLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQ 316 Query: 321 AKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYL 380 + +EE+ ++G S +D + M Y + E R VP + Sbjct: 317 QRCREEVREILGDQDSFQWEDLAKMTYLTMCMKECFRLYPPVPQVYRQLSKPVSFVDGRS 376 Query: 381 IPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGL 440 +P G+ I + ++ + +P+P +FDP F +N + + F+PFSAG R C G+ Sbjct: 377 LPAGSLISLHIYALHRNSDVWPDPEVFDPLRFSPENSSGRHPYAFIPFSAGPRNCIGQQF 436 Query: 441 ARMELFLFLTTILQNFNLKSVDDLK 465 A E+ + L F SVD L+ Sbjct: 437 AMNEMKVVTALCLLRFEF-SVDPLR 460 >2Y5N-A nrPDB Length = 417 Score = 218 bits (554), Expect = 7e-57, Method: Composition-based stats. Identities = 78/417 (18%), Positives = 145/417 (34%), Gaps = 73/417 (17%) Query: 76 VFHGYEAVKEALIDNGEEFSGRGNSPISQRITKG----LGIISSNGKRWKEIRRFSLTTL 131 + YE V+ L D F + + T+ G++S + +RR + Sbjct: 65 LVTRYEDVRAVLGDG--RFVRGPSMTRDEPRTRPEMVKGGLLSMDPPEHSRLRRLVVKAF 122 Query: 132 RNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNVICSVVFQKRFDYK 190 S+ R +E AH LV+++ T P D + P VIC ++ D+ Sbjct: 123 T--ARRAESLRPRAREIAHELVDQMAAT-GQPADLVAMFARQLPVRVICELLGVPSADHD 179 Query: 191 DQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKE 250 F F + T ++ + +Y+ + + Sbjct: 180 --RFTRWSGAFLSTAEV---------------------TAEEMQEAAEQAYAYMGDLIDR 216 Query: 251 HQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGL 310 + P D + L++ +Q+ + + L+ L VAG E+T+T + + Sbjct: 217 RRK-----EPTDDLVSALVQAR----DQQDSLSEQELLDLAIGLLVAGYESTTTQIADFV 267 Query: 311 LLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDL-VPTGVPHA 369 LL+ PE+ ++ + + + + V E+ R+ L V T P Sbjct: 268 YLLMTRPELRRQLLDRPELI------------------PSAVEELTRWVPLGVGTAFPRY 309 Query: 370 VTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFS 429 D R I G ++A + D +FP+ + D + + F Sbjct: 310 AVEDVTLRGVTIRAGEPVLASTGAANRDQAQFPDADRIDVDR---------TPNQHLGFG 360 Query: 430 AGKRICAGEGLARMELFLFLTTILQNF---NLKSVDDLKNLNTTAVTKGIVSLPPSY 483 G C G LAR+EL + L +LQ L + + + +G + LP + Sbjct: 361 HGVHHCLGAPLARVELQVALEVLLQRLPGIRLGIPETQLRWSEGMLLRGPLELPVVW 417 >3L4D-A nrPDB Length = 453 Score = 216 bits (551), Expect = 1e-56, Method: Composition-based stats. Identities = 81/455 (17%), Positives = 157/455 (34%), Gaps = 25/455 (5%) Query: 26 RRKLPPGPTPL-PIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVK 84 + KLPP P +G+++Q KD K YG +FT+ N I V Sbjct: 1 KGKLPPVVHGTTPFVGHIIQFG-KDPLGFMLKAKKKYGGIFTMNICGNRITVVGDVHQHS 59 Query: 85 EALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDR 144 + E S R + ++ R +E F L ++ Sbjct: 60 KFFTPRNEILSPREVYSFMVPVFGEGVAYAAPYPRMREQLNFLAEELTVAKF--QNFAPS 117 Query: 145 VQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNEN 204 +Q E ++ + N C +F +D ++F + Sbjct: 118 IQHEVRKFMKANWNKDEGEINILDDCSAMIINTACQCLFG-----EDLRKRLDARQFAQL 172 Query: 205 FRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKV--KEHQASLDVNNPRD 262 + S I P ++ + A + + E + +E + + N D Sbjct: 173 LAKMESCLIPAAVFLPWILKLPLPQSYRCRDARAELQDILSEIIIAREKEEAQKDTNTSD 232 Query: 263 FIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLL--KHPEVT 320 + L + ++ + + + G + AG T++ T + LL L+ ++ Sbjct: 233 LLAGLLGAVYRDG----TRMSQHEVCGMIVAAMFAGQHTSTITTTWSLLHLMDPRNKRHL 288 Query: 321 AKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYL 380 AK+ +EID + + + MP+ + E R + + V + Y+ Sbjct: 289 AKLHQEIDEFPAQLNYDNVME--EMPFAEQCARESIRRDPPL-VMLMRKVLKPVQVGKYV 345 Query: 381 IPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGL 440 +P+G I D++ FPNP ++P + F F AG C GE Sbjct: 346 VPEGDIIACSPLLSHQDEEAFPNPREWNPERNMKLVD-----GAFCGFGAGVHKCIGEKF 400 Query: 441 ARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKG 475 +++ L T+L++++ + + L N + G Sbjct: 401 GLLQVKTVLATVLRDYDFELLGPLPEPNYHTMVVG 435 >3JUS-A nrPDB Length = 461 Score = 215 bits (548), Expect = 3e-56, Method: Composition-based stats. Identities = 75/463 (16%), Positives = 155/463 (33%), Gaps = 29/463 (6%) Query: 19 LWRQSCRRR-KLPPGPT-PLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVV 76 + +++ K PP P+P +G+ + I N + YGPVF+ Sbjct: 1 MAKKTLPAGVKSPPYIFSPIPFLGHAIAFGKSPIE-FLENAYEKYGPVFSFTMVGKTFTY 59 Query: 77 FHGYEAVKEALIDNGEEFSGRGNSPISQRIT--KGLGIISSNG-KRWKEIRRFSLTTLRN 133 G +A AL+ N + S+ T G G+ + E ++ + L Sbjct: 60 LLGSDAA--ALLFNSKNEDLNAEDVYSRLTTPVFGKGVAYDVPNPVFLEQKKMLKSGLNI 117 Query: 134 FGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQN 193 + +++E E ++ A +I + ++ Sbjct: 118 AHF--KQHVSIIEKETKEYFESWGESGEKNV------FEALSELIILTASHCLHGKEIRS 169 Query: 194 FLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQA 253 L ++ + + L+ + P + + + + + + +++ + Sbjct: 170 QLN--EKVAQLYADLDGGFSHAAWLLPGWLPLP--SFRRRDRAHREIKDIFYKAIQKRRQ 225 Query: 254 SLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLL 313 S D + L ++ + + G + L +AG T+STT + L Sbjct: 226 SQ--EKIDDILQTLLDATYKDG----RPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFL 279 Query: 314 LKHPEVTAKVQEEIDHVIGRHRSPCMQDR-SHMPYTDAVVHEIQRYSDLVPTGVPHAVTT 372 + + K E V G + P D+ + D + E R + + T Sbjct: 280 ARDKTLQKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMIMM-RMART 338 Query: 373 DTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGK 432 Y IP G + T + F+P +L N + ++PF AG+ Sbjct: 339 PQTVAGYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGR 398 Query: 433 RICAGEGLARMELFLFLTTILQNFNLKSVDDL-KNLNTTAVTK 474 C GE A +++ +T+L+ + +D +N T + Sbjct: 399 HRCIGENFAYVQIKTIWSTMLRLYEFDLIDGYFPTVNYTTMIH 441 >3A50-A nrPDB Length = 411 Score = 215 bits (547), Expect = 4e-56, Method: Composition-based stats. Identities = 82/446 (18%), Positives = 135/446 (30%), Gaps = 73/446 (16%) Query: 46 DVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQR 105 ++ ++ PV + P+ + Y V+EA +D R P QR Sbjct: 18 FWQNPHPAYAALRAE-DPVRKLALPDGPVWLLTRYADVREAFVDPRLSKDWRHRLPEDQR 76 Query: 106 ITKG----LGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKA 161 +I + +R+ + M +E R+ E A L+ L Sbjct: 77 ADMPATPTPMMILMDPPDHTRLRKLVGRSFTVRRM--NELEPRITEIADGLLAGLPTDG- 133 Query: 162 SPCDP-TFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFP 220 P D P VIC ++ D D S W V Sbjct: 134 -PVDLMREYAFQIPVQVICELLGLPAEDRDD-----------------FSAWSSV----- 170 Query: 221 LLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKS 280 L+D P + Y+ + ++ + D D L + D Sbjct: 171 -LVDDSPADDKNA--AMGKLHGYLSDLLERKRTEPD--------DALLSSLLAVSDMDGD 219 Query: 281 EFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQ 340 + E LV L +AG ETT + G+L LL HP+ + E+ + Sbjct: 220 RLSQEELVAMAMLLLIAGHETTVNLIGNGVLALLTHPDQRKLLAEDPSLI---------- 269 Query: 341 DRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKE 400 + V E R+ V D + IP G +M L + D Sbjct: 270 --------SSAVEEFLRFDSPVSQAPIRFTAEDVTYSGVTIPAGEMVMLGLAAANRDADW 321 Query: 401 FPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTIL---QNFN 457 P P+ D + + F G C G LAR+E + + + Sbjct: 322 MPEPDRLDITR---------DASGGVFFGHGIHFCLGAQLARLEGRVAIGRLFADRPELA 372 Query: 458 LKSVDDLKNLNTTAVTKGIVSLPPSY 483 L D + + +G+ +P + Sbjct: 373 LAVGLDELVYRRSTLVRGLSRMPVTM 398 >6CR2-A nrPDB Length = 477 Score = 214 bits (545), Expect = 8e-56, Method: Composition-based stats. Identities = 82/478 (17%), Positives = 167/478 (34%), Gaps = 51/478 (10%) Query: 27 RKLPPGPTPL-PIIGNMLQIDVKDICKSFTNFSKVYGPVFT-VYFGMNPIVVFH--GYEA 82 +K PP P IG+ + + D K F + YG +FT + G V G + Sbjct: 3 KKTPPVVFHWFPFIGSTISYGI-DPYKFFFDCRAKYGDIFTFILLGKKTTVYLGTKGNDF 61 Query: 83 VKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIE 142 + + + SP++ + + + E ++F L + + RS Sbjct: 62 ILNG--KLRDVCAEEVYSPLTTPVFGRHVVYDCPNAKLMEQKKFVKYGLTSDAL--RSYV 117 Query: 143 DRVQEEAHCLVEE---LRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYK-DQNFLTLM 198 + +E V+ + K D + + K K D F L Sbjct: 118 PLITDEVESFVKNSPAFQGHKGV-FDVCKTIAEITIYTASRSLQGKEVRSKFDSTFAELY 176 Query: 199 KRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVN 258 + F + NF L P + LT +Y+ E +K + + Sbjct: 177 HNLDMGFAPI---------NFMLPWAPLPHNRKRDAAQRKLTETYM-EIIKARRQAGSKK 226 Query: 259 NPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPE 318 + D + + + + + E + + L +AG ++S+T + +L L P+ Sbjct: 227 DSEDMVWNLMSCVYK----NGTPVPDEEIAHMMIALLMAGQHSSSSTASWIVLRLATRPD 282 Query: 319 VTAKVQEEIDHVIGRHRSPCMQD-RSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFR 377 + ++ +E V+G P D + V+ E R + + + AV Sbjct: 283 IMEELYQEQIRVLGSDLPPLTYDNLQKLDLHAKVIKETLRLHAPIHS-IIRAVKNPMAVD 341 Query: 378 N--YLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNF---------------- 419 Y+IP +++ ++ FPNP ++P + + Sbjct: 342 GTSYVIPTSHNVLSSPGVTARSEEHFPNPLEWNPHRWDENIAASAEDDEKVDYGYGLVSK 401 Query: 420 KKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLK---SVDDLKNLNTTAVTK 474 + ++PF AG+ C GE A ++L +++ F + VD + + + +++ Sbjct: 402 GTNSPYLPFGAGRHRCIGEQFAYLQLGTITAVLVRLFRFRNLPGVDGIPDTDYSSLFS 459 >2ZBZ-A nrPDB Length = 412 Score = 213 bits (543), Expect = 1e-55, Method: Composition-based stats. Identities = 80/447 (17%), Positives = 145/447 (32%), Gaps = 79/447 (17%) Query: 50 ICKSFTNFSKVYGPV--FTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGN--SPISQR 105 + + GP+ T+Y G VV +EA ++ L D S R + P + Sbjct: 26 LPDGYAQLRDTPGPLHRVTLYDGRQAWVV-TKHEAARKLLGDPRLS-SNRTDDNFPATSP 83 Query: 106 ITKG-----LGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTK 160 + I + RR +++ + + + V+E H ++E+ Sbjct: 84 AFEAVRESPQAFIGLDPPEHGTRRRMTISEFTVKRI--KGMRPEVEEVVHGFLDEMLA-A 140 Query: 161 ASPCDPTFILGCA-PCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNF 219 D P VIC ++ Y D F F+ + +Q + Sbjct: 141 GPTADLVSQFALPVPSMVICRLLG---VPYADHEF----------FQDASKRLVQSTD-- 185 Query: 220 PLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQK 279 L Y+ + + Q L+ Sbjct: 186 ----------AQSALTARNDLAGYLDGLITQFQTEPGAG---------LVGALVADQLAN 226 Query: 280 SEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCM 339 E + E L+ T L +AG ETT++ ++ LL HPE A ++ + V G Sbjct: 227 GEIDREELISTAMLLLIAGHETTASMTSLSVITLLDHPEQYAALRADRSLVPG------- 279 Query: 340 QDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDK 399 V E+ RY + T D + LI G ++ + + D Sbjct: 280 -----------AVEELLRYLAIADIAGGRVATADIEVEGQLIRAGEGVIVVNSIANRDGT 328 Query: 400 EFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQN---F 456 + +P+ D + + + + F G C G+ LAR+EL + L ++ Sbjct: 329 VYEDPDALDI---------HRSARHHLAFGFGVHQCLGQNLARLELEVILNALMDRVPTL 379 Query: 457 NLKSVDDLKNLNTTAVTKGIVSLPPSY 483 L + L +G+ LP ++ Sbjct: 380 RLAVPVEQLVLRPGTTIQGVNELPVTW 406 >4YZR-A nrPDB Length = 405 Score = 212 bits (540), Expect = 3e-55, Method: Composition-based stats. Identities = 67/374 (17%), Positives = 127/374 (33%), Gaps = 65/374 (17%) Query: 112 IISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILG 171 +++ + +R + ++ +++ A L++E+ K + Sbjct: 91 MLAKDTPDHTRLRSLVHQAFTPRTI--ENLRGSIEQIAEQLLDEMEKENKADI-MKSFAS 147 Query: 172 CAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHN 231 P VI ++ + D Q+ N ++D G Sbjct: 148 PLPFIVISELMGIPKEDRSQ---------------------FQIWTNA--MVDTSEGNRE 184 Query: 232 KVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTV 291 + + + YI + + + + P+D + L+ E+ S+ + + L + Sbjct: 185 LTNQALREFKDYIAKLIHDRRI-----KPKDDLISKLVHAEE----NGSKLSEKELYSML 235 Query: 292 ADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAV 351 L VAG ETT L G L LL+H + K++++ + + Sbjct: 236 FLLVVAGLETTVNLLGSGTLALLQHKKECEKLKQQPEMIA------------------TA 277 Query: 352 VHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGH 411 V E+ RY+ V D ++ + I +G I + S D F NP I + Sbjct: 278 VEELLRYTSPVVMMANRWAIEDFTYKGHSIKRGDMIFIGIGSANRDPNFFENPEILNINR 337 Query: 412 FLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF---NLKSVDDLKNLN 468 + + F G C G LAR+E + +L+ F L D Sbjct: 338 ---------SPNRHISFGFGIHFCLGAPLARLEGHIAFKALLKRFPDIELAVAPDDIQWR 388 Query: 469 TTAVTKGIVSLPPS 482 +G+ SLP S Sbjct: 389 KNVFLRGLESLPVS 402 >3R9C-A nrPDB Length = 418 Score = 211 bits (536), Expect = 7e-55, Method: Composition-based stats. Identities = 68/402 (16%), Positives = 124/402 (30%), Gaps = 65/402 (16%) Query: 88 IDNGEEFSGRGNSPISQRIT---------KGLGIISSNGKRWKEIRRFSLTTLRNFGMGK 138 + + S R S I QR + + +R + Sbjct: 64 LRHPSSCSDRTKSTIFQRQLAAETQPRPQGPASFLFLDPPDHTRLRGLVSKAFAPRVI-- 121 Query: 139 RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNVICSVVFQKRFDYKDQNFLTL 197 + +E + L++ + + L P VIC ++ D F Sbjct: 122 KRLEPEITALVDQLLDAV---DGPEFNLIDNLAYPLPVAVICRLLGVPIEDE--PKFSRA 176 Query: 198 MKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDV 257 + + + F ++ +K R Y+R + E + + Sbjct: 177 SALLAAALDPFLALTGETSDLF-----------DEQMKAGMWLRDYLRALIDERRRT--- 222 Query: 258 NNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHP 317 P + + L+ +E+ D + + ++ T L +AG ETT + L +L+ P Sbjct: 223 --PGEDLMSGLVAVEESGD----QLTEDEIIATCNLLLIAGHETTVNLIANAALAMLRTP 276 Query: 318 EVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFR 377 A + + AV+ E RY V V D Sbjct: 277 GQWAALAADGSR------------------ASAVIEETMRYDPPVQL-VSRYAGDDLTIG 317 Query: 378 NYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAG 437 + +PKG T++ LL + D P+ FDP + + F G C G Sbjct: 318 THTVPKGDTMLLLLAAAHRDPTIVGAPDRFDPDRAQIR---------HLGFGKGAHFCLG 368 Query: 438 EGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSL 479 LAR+E + L + F + +G+ +L Sbjct: 369 APLARLEATVALPALAARFPEARLSGEPEYKRNLTLRGMSTL 410 >5IT1-A nrPDB Length = 399 Score = 210 bits (534), Expect = 1e-54, Method: Composition-based stats. Identities = 74/418 (17%), Positives = 138/418 (33%), Gaps = 75/418 (17%) Query: 76 VFHGYEAVKEALIDNGEEFS-------GRGNSPISQRITKGLGIISSNGKRWKEIRRFSL 128 + GYE V+ L D FS + ++Q+ +G ++ + + R+ Sbjct: 47 LVTGYEQVRAVLRD--PSFSVGVPHALHTQDGVVTQKPGRG-SLLWQDAPEHTDDRKLLA 103 Query: 129 TTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFD 188 M +++ +Q ++ + + P D +++ S +F + Sbjct: 104 KEFTVRRM--QALRPNIQRIVDEHLDAIEA-RGGPVDLVKTFANPVPSMVISDLFGVPAE 160 Query: 189 YKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKV 248 + F + + + + + + V Sbjct: 161 RR-AEFQEIAEAMMRVDQDAAAT----------------------EAAGMRLGGLLYQLV 197 Query: 249 KEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRY 308 +E +A NP D + LI E + D + + N GT L +A +TT+ + Sbjct: 198 QERRA-----NPGDDLISALITTE-DPDGVIDDMFLMNAAGT---LLIAAHDTTACMIGL 248 Query: 309 GLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPH 368 G LLL P+ A +Q++ + V E+ RY + G Sbjct: 249 GTALLLDRPDQLALLQKDPSLI------------------GNAVEELLRYLTIGQFGAER 290 Query: 369 AVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPF 428 T D + I KG ++ L S D +P FD + + F Sbjct: 291 VATQDGEIGGVRIAKGEQVVTHLLSADFDPAFVEDPERFDITR---------RPAPHLAF 341 Query: 429 SAGKRICAGEGLARMELFLFLTTILQNF---NLKSVDDLKNLNTTAVTKGIVSLPPSY 483 G C G+ LAR+EL + T+ + F L + V G+ LP ++ Sbjct: 342 GFGAHQCIGQQLARIELQIVFGTLFRRFPTLRLAKPVEELRFRNDMVFYGVHELPVTW 399 >5L94-A nrPDB Length = 410 Score = 210 bits (534), Expect = 1e-54, Method: Composition-based stats. Identities = 70/407 (17%), Positives = 136/407 (33%), Gaps = 61/407 (14%) Query: 77 FHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGM 136 Y+ VKE L S R ++ G +I+ + + E+R M Sbjct: 49 VFHYDGVKEVLEQKNIFSSDRRPPQNQRQTALGTSLINIDPPKHAEMRALVNKAFTPKAM 108 Query: 137 GKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNVICSVVFQKRFDYKDQNFL 195 ++ E ++ + L++E+ + D L P VI ++ +DQ Sbjct: 109 --KAWEPKIARITNELLQEVEHLED--IDIVEHLSYPLPVMVIADILG---VPIEDQRQF 161 Query: 196 TLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASL 255 I+ P + + +K +Y ++E + Sbjct: 162 KDWSDI-----IVAGPSNNE-------RETLEKLQQEKMKANDELETYFYRIIEEKR--- 206 Query: 256 DVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLK 315 P D I L++ ++E + E +VG L +AG ETT+ + + L++ Sbjct: 207 --TRPGDDIISVLLQAKEEGK----QLTDEEIVGFSILLLIAGNETTTNLISNTIYCLME 260 Query: 316 HPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTK 375 +++ E + + + E+ RY V + V D Sbjct: 261 DKASFERLKREKE------------------LLPSGIEEVLRYRSPVQ-ALHRIVKEDVT 301 Query: 376 FRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRIC 435 + G ++ + S D + F +P +F K + M F G C Sbjct: 302 LAGKKLKAGEHVVPWMGSAHRDAEYFEDPEVFKIDR---------KPNVHMAFGRGIHFC 352 Query: 436 AGEGLARMELFLFLTTILQNF---NLKSVDDLKNLNTTAVTKGIVSL 479 G LAR+E + L ++ + + +LK + + G+ L Sbjct: 353 LGAPLARIEAKIMLAELIDRYPQMDWSPSFELKPI-ESTFVYGLKEL 398 >4Z5P-A nrPDB Length = 400 Score = 209 bits (532), Expect = 2e-54, Method: Composition-based stats. Identities = 77/417 (18%), Positives = 142/417 (34%), Gaps = 73/417 (17%) Query: 76 VFHGYEAVKEALIDNGEEFS----GRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTL 131 + Y+ V+ A D FS G + + I+S + +RR Sbjct: 48 MVTRYDDVRAANSD--PRFSRAQIGEDTPRTTPLARRSDTILSLDPPEHTRLRRLLSKAF 105 Query: 132 RNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNVICSVVFQKRFDYK 190 MG +++ ++E L++ + +T P D L VIC ++ Y+ Sbjct: 106 TARRMG--AMQSWLEELFAGLLDGVERT-GHPADIVRDLAQPFTIAVICRLLG---VPYE 159 Query: 191 DQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKE 250 D+ W +V + + + A R+Y+ + V Sbjct: 160 DRGRFQ--------------HWSEVIMSTTAYSK------EEAVSADASIRAYLADLVSA 199 Query: 251 HQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGL 310 +A+ P D + L+ + D + L+ L VAG ET++ L + Sbjct: 200 RRAA-----PHDDLLGVLVSARDDDD----RLTEDELITFGVTLLVAGHETSAHQLGNMV 250 Query: 311 LLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLV-PTGVPHA 369 LL H + + ++E+ + V E+ R+ L G Sbjct: 251 YALLTHEDQLSLLREQPE------------------LLPRAVEELLRFVPLGNGVGNARI 292 Query: 370 VTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFS 429 D + + G ++A + D + F +P+ D + + + F Sbjct: 293 ALEDVELSGGTVRAGEGVVAAAVNANRDPRAFDDPDRLDITR---------EKNPHLAFG 343 Query: 430 AGKRICAGEGLARMELFLFLTTILQNF---NLKSVDDLKNLNTTAVTKGIVSLPPSY 483 G C G LARMEL + + +L+ F L D T + +G LP ++ Sbjct: 344 HGAHYCLGAQLARMELRVAIGGLLERFPGLRLAVPADQVEWKTGGLFRGPQRLPIAW 400 >5EX6-C nrPDB Length = 434 Score = 208 bits (530), Expect = 4e-54, Method: Composition-based stats. Identities = 74/439 (16%), Positives = 142/439 (32%), Gaps = 83/439 (18%) Query: 62 GPVFTVYFGM----NPIVVFHGYEAVKEALIDNGEEFSGRGNSP---------ISQRITK 108 G + V G + G++ V++ L D+ FS R + + Sbjct: 62 GELTRVRLGSGADAEHTWLATGHDVVRQVLGDHT-RFSTRRRFDRNDEIGGKGVFRPREL 120 Query: 109 GLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTF 168 ++ + +RR + + R + +++ ++E+ + SP D Sbjct: 121 VGNLMDYDPPEHTRLRRLLAPGFTHRKI--RRMAPYIEQIVTERLDEMERE-GSPADLIE 177 Query: 169 ILG-CAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFP 227 + P V+C ++ R D FL L R + Sbjct: 178 LFADEVPGPVLCELLGVPRDDR--AMFLQLCHRHLD------------------------ 211 Query: 228 GTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENL 287 R+ E + ++ +D D + + E + E L Sbjct: 212 ------ASLSGRRRAAAGEAFSRYLVTMVARERKDPGDGLIGMVVAEHGDT---VTDEEL 262 Query: 288 VGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPY 347 G + +AG + S + G+L LL++PE A ++ ++ P Sbjct: 263 RGVCVQMMLAGDDNISGMIGLGVLALLRNPEQIAALRGDV------------------PA 304 Query: 348 TDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIF 407 + V E+ RY + P D+ + +I G T++ L + D P+ + Sbjct: 305 AERAVDELIRYLTVPYAPTPRTAIEDSTVGDQVIKAGETVLCSLPTANRDPALLPDADRL 364 Query: 408 DPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF---NLKSVDDL 464 D ++ + F G C G LAR+EL + T + + F L D Sbjct: 365 DVTR---------EAVPHVAFGHGVHHCLGAALARLELRIAYTALWRRFPDLRLADPDGA 415 Query: 465 KNLNTTAVTKGIVSLPPSY 483 + GI L ++ Sbjct: 416 TEFRLSTPAYGISRLMVTW 434 >4WPZ-A nrPDB Length = 397 Score = 208 bits (530), Expect = 4e-54, Method: Composition-based stats. Identities = 71/423 (16%), Positives = 142/423 (33%), Gaps = 81/423 (19%) Query: 76 VFHGYEAVKEALIDNGEEFSGRGNSPISQRITK-----GLGIISSNGKRWKEIRRFSLTT 130 + + V++ L+D+ + + T+ ++ + +R+ Sbjct: 41 MVTKHADVRKVLVDSRFSSKVMATAAAAMSETETGKLMNESLVGMDAPEHTRLRKLVTKA 100 Query: 131 LRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNVICSVVFQKRFDY 189 ++ R+ E L++EL P D P VIC ++ D Sbjct: 101 FT--ARRVETLRPRITELVGQLLDELETLP-RPVDLVKNFSVPLPVRVICELLGVPAGD- 156 Query: 190 KDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVAL---TRSYIRE 246 + F + G +V++ A +Y E Sbjct: 157 --------------------------QDTFHAWSNALLGDWQQVVEKEAATVSLVNYFGE 190 Query: 247 KVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTL 306 + + NP D + LI + + S ++ + AG ETT+ + Sbjct: 191 LIAVKRE-----NPADDLISELIAIS----DGDSTLTEREIIALSIGILSAGHETTANQI 241 Query: 307 RYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTG- 365 L+ LL +PE K+++ + + V E+ R+ L TG Sbjct: 242 SMFLVTLLHNPEELDKLRDNREAI------------------PKAVDELLRFVPLTTTGG 283 Query: 366 -VPHAVTTDTKF-RNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSD 423 +P T + + ++P G ++ + + D + F + + +++ Sbjct: 284 IIPRLTTAEVELSGGQVLPAGAVVLPAVATANRDPEVFEDGERLNVTR---------ENN 334 Query: 424 YFMPFSAGKRICAGEGLARMELFLFLTTILQNF---NLKSVDDLKNLNTTAVTKGIVSLP 480 + F AG C G LAR+EL L IL L + L + ++ +G+ SLP Sbjct: 335 PHLAFGAGIHHCLGAQLARIELQEALGAILDRMPQVRLAVPESELRLKSASIIRGLESLP 394 Query: 481 PSY 483 ++ Sbjct: 395 ITW 397 >2W0A-A nrPDB Length = 455 Score = 208 bits (528), Expect = 6e-54, Method: Composition-based stats. Identities = 74/430 (17%), Positives = 146/430 (33%), Gaps = 21/430 (4%) Query: 43 LQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPI 102 L+ D G V T +V+ G A E G++ + + Sbjct: 19 LEEFRTDPIGLMQRVRDELGDVGTFQLAGKQVVLLSGSHA-NEFFFRAGDDDLDQAKAYP 77 Query: 103 SQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKAS 162 G ++ R+ L G + ++++ ++ + +A Sbjct: 78 FMTPIFGEAVVFDASPE---RRKEMLHNAALRGEQMKGHAATIEDQVRRMIADW--GEAG 132 Query: 163 PCDPTFILGCAPCNVICSVVFQKRF-DYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPL 221 D + + K+F D D F L P V P Sbjct: 133 EIDLLDFFAELTIYTSSACLIGKKFRDQLDGRFAKLYHELERG----TDPLAYVDPYLP- 187 Query: 222 LIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSE 281 I+ F VAL + ++ RD +D LI ++ E Sbjct: 188 -IESFRRRDEARNGLVALVADIMNGRIANPPTDKSD---RDMLD-VLIAVKAETGTP--R 240 Query: 282 FNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQD 341 F+ + + G + AG T+S T + L+ L++H + A V +E+D + G RS Sbjct: 241 FSADEITGMFISMMFAGHHTSSGTASWTLIELMRHRDAYAAVIDELDELYGDGRSVSFHA 300 Query: 342 RSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEF 401 +P + V+ E R + + + + + + I +G + A ++F Sbjct: 301 LRQIPQLENVLKETLRLHPPLII-LMRVAKGEFEVQGHRIHEGDLVAASPAISNRIPEDF 359 Query: 402 PNPNIFDPGHFLD-KNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKS 460 P+P+ F P + + + ++PF AG+ C G A M++ + +L+ + + Sbjct: 360 PDPHDFVPARYEQPRQEDLLNRWTWIPFGAGRHRCVGAAFAIMQIKAIFSVLLREYEFEM 419 Query: 461 VDDLKNLNTT 470 ++ Sbjct: 420 AQPPESYRND 429 >3N9Z-A nrPDB Length = 487 Score = 207 bits (526), Expect = 1e-53, Method: Composition-based stats. Identities = 84/473 (17%), Positives = 170/473 (35%), Gaps = 31/473 (6%) Query: 31 PGPTPLPIIGNML-QIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALID 89 PG + + + + + YGP++ G V E V Sbjct: 14 PGDNGWLNLYHFWRETGTHKVHLHHVQNFQKYGPIYREKLGNVESVYVIDPEDVALLFKS 73 Query: 90 NG---EEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQ 146 G E F Q + +G++ WK+ R +L ++ + Sbjct: 74 EGPNPERFLIPPWVAYHQYYQRPIGVLLKKSAAWKKDR-VALNQEVMAPEATKNFLPLLD 132 Query: 147 EEAHCLVEELRK------TKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKR 200 + V L + + D + L I +V+F +R ++ +R Sbjct: 133 AVSRDFVSVLHRRIKKAGSGNYSGDISDDLFRFAFESITNVIFGERQGMLEEVVNPEAQR 192 Query: 201 FNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQAS-----L 255 F + + + + N P L F K K+ I K + + Sbjct: 193 FIDAIYQMFHTSVPMLNLPPDLFRLF---RTKTWKDHVAAWDVIFSKADIYTQNFYWELR 249 Query: 256 DVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLK 315 + L ++ + S+ + E++ V ++ G +TTS TL++ L + + Sbjct: 250 QKGSVHHDYRGILYRLLGD-----SKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMAR 304 Query: 316 HPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTK 375 + +V ++ E+ + + +P A + E R + + + D Sbjct: 305 NLKVQDMLRAEVLAARHQAQGDMATMLQLVPLLKASIKETLRLHPIS-VTLQRYLVNDLV 363 Query: 376 FRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRIC 435 R+Y+IP T + + ++ + F +P FDP +L K+ N + F G R C Sbjct: 364 LRDYMIPAKTLVQVAIYALGREPTFFFDPENFDPTRWLSKDKNI-TYFRNLGFGWGVRQC 422 Query: 436 AGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFI 488 G +A +E+ +FL +L+NF ++ +++L+ T ++ +P I F Sbjct: 423 LGRRIAELEMTIFLINMLENFRVE----IQHLSDVGTTFNLILMPEK-PISFT 470 >3ABA-A nrPDB Length = 403 Score = 206 bits (525), Expect = 1e-53, Method: Composition-based stats. Identities = 74/419 (17%), Positives = 139/419 (33%), Gaps = 75/419 (17%) Query: 76 VFHGYEAVKEALIDNGEEFSGR-------GNSPISQRITKGLGIISSNGKRWKEIRRFSL 128 + GYE V+ L D+ FS + + ++Q+ +G ++ + R+ Sbjct: 47 LVTGYEEVRALLRDS--SFSVQVPHALHTQDGVVTQKPGRG-SLLWQDEPEHTSDRKLLA 103 Query: 129 TTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFD 188 M +++ +Q ++ + + P D A +++ S +F + Sbjct: 104 KEFTVRRM--QALRPNIQRIVDEHLDAIEA-RGGPVDLVKTFANAVPSMVISDLFGVPVE 160 Query: 189 YKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKV 248 + F + + + + + + V Sbjct: 161 RR-AEFQDIAEAMMRVDQDAAAT----------------------EAAGMRLGGLLYQLV 197 Query: 249 KEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRY 308 +E +A NP D + LI E + D + + N GT L +A +TT+ + Sbjct: 198 QERRA-----NPGDDLISALITTE-DPDGVVDDMFLMNAAGT---LLIAAHDTTACMIGL 248 Query: 309 GLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPH 368 G LLL P+ A ++E+ V V E+ RY + G Sbjct: 249 GTALLLDSPDQLALLREDPSLV------------------GNAVEELLRYLTIGQFGGER 290 Query: 369 AVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPF 428 T D + I KG ++A + + D P FD + + F Sbjct: 291 VATRDVELGGVRIAKGEQVVAHVLAADFDPAFVEEPERFDITR---------RPAPHLAF 341 Query: 429 SAGKRICAGEGLARMELFLFLTTILQN---FNLKSVDDLKNLNTTAVTKGIVSLPPSYQ 484 G C G+ LAR+EL + T+ + L + V G+ LP ++ Sbjct: 342 GFGAHQCIGQQLARIELQIVFETLFRRLPGLRLAKPVEELRFRHDMVFYGVHELPVTWH 400 >5YSW-A nrPDB Length = 441 Score = 206 bits (523), Expect = 2e-53, Method: Composition-based stats. Identities = 80/453 (17%), Positives = 151/453 (33%), Gaps = 80/453 (17%) Query: 49 DICKSFTNFSKVYGPVFTVYFGM-NPIVVFHGYEAVKEALID---NGEEFSGRG----NS 100 + + S+ GPV +P + GYE + L D + + F S Sbjct: 52 HVPPALVAVSER-GPVARATLAAGDPFWLVSGYEEARAVLSDPRFSSDRFQYHPWFKELS 110 Query: 101 PISQRITK-----GLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEE 155 P + + I+ + R+ + R + R+ E V+ Sbjct: 111 PEFRERLRDDKARAGSFINMDPPEHTRYRKLLTGQFTVRRI--RELGARIDEIVAGRVDA 168 Query: 156 LRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQV 215 + + T AP +IC ++ + D F + Sbjct: 169 MLAGGTTADLMTEFAFPAPSLMICELLGVRYEDR--AEFQQRASALLQ------------ 214 Query: 216 CNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEK 275 + +KN R++++ V + +A NP I LI Sbjct: 215 ----------MNAPVAEAVKNADALRAFMQALVTDKRA-----NPAGDIISGLIH----H 255 Query: 276 DNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHR 335 + L+ L +AG +TT++ L G+ +LL+ P A ++++ + Sbjct: 256 AGADPALTDDELINIANLLLIAGYDTTASMLGLGIFVLLQRPAQLATLRDDPSRIAD--- 312 Query: 336 SPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVL 395 V E+ RY +V G+ D +F IP G+T++ + + Sbjct: 313 ---------------AVEELLRYLSVVNPGIFRFAKEDLEFAGEHIPAGSTVVVSVVATN 357 Query: 396 HDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQN 455 D + +P+P++ + + F G C G+ LARME+ +L+ Sbjct: 358 RDARHWPDPDL----------DLTRPRGPHLAFGHGVHQCLGQQLARMEMQAGYAELLRR 407 Query: 456 F---NLKSVDDLKNLNTTAVTKGIVSLPPSYQI 485 L + L +T G+ SLP ++ Sbjct: 408 LPNVRLAVPPEEVPLRNDMLTYGVHSLPIAWDA 440 >3ABB-A nrPDB Length = 408 Score = 204 bits (520), Expect = 5e-53, Method: Composition-based stats. Identities = 82/423 (19%), Positives = 139/423 (32%), Gaps = 75/423 (17%) Query: 72 NPIVVFHGYEAVKEALID-NGEEFSGRGNSPISQRITKGLG-----IISSNGKRWKEIRR 125 P + G+ + L+D G + P+ R T+ G +I + RR Sbjct: 48 RPAWLITGHAEGRALLVDPRLSSDWGHPDFPVVVRRTEDRGGLAFPLIGVDDPVHARQRR 107 Query: 126 FSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNV-ICSVVFQ 184 + + M +I R+Q L++++ K D +V IC ++ Sbjct: 108 MLIPSFGVKRM--NAIRPRLQSLVDRLLDDMLA-KGPGADLVSAFALPVPSVAICELLG- 163 Query: 185 KRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYI 244 Y D +F R +Y+ Sbjct: 164 --VPYGDHDFFEECSRNFVGAATSAE----------------------ADAAFGELYTYL 199 Query: 245 REKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTST 304 V QA P D + LI + E+ + + + +V L VAG ETT Sbjct: 200 HGLVGRKQA-----EPEDGLLDELIARQLEEG----DLDHDEVVMIALVLLVAGHETTVN 250 Query: 305 TLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPT 364 + G L L++HPE + + V G VV E+ R++ V Sbjct: 251 AIALGALTLIQHPEQIDVLLRDPGAVSG------------------VVEELLRFTS-VSD 291 Query: 365 GVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDY 424 + D + I G ++ +T + D K + NP+IFD + + + Sbjct: 292 HIVRMAKEDIEVGGATIKAGDAVLVSITLMNRDAKAYENPDIFD---------ARRNARH 342 Query: 425 FMPFSAGKRICAGEGLARMELFLFLTTILQN---FNLKSVDDLKNLNTTAVTKGIVSLPP 481 + F G C G+ LAR EL + L + L D + +G + LP Sbjct: 343 HVGFGHGIHQCLGQNLARAELEIALGGLFARIPGLRLAVPLDEVPIKAGHDAQGPIELPV 402 Query: 482 SYQ 484 + Sbjct: 403 VWH 405 >5OFQ-A nrPDB Length = 409 Score = 202 bits (513), Expect = 3e-52, Method: Composition-based stats. Identities = 67/379 (17%), Positives = 130/379 (34%), Gaps = 62/379 (16%) Query: 111 GIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFIL 170 I+ + + ++R + + +E ++E A L++E+ + D Sbjct: 82 SILMMDPPKHTKLRNLVNKAFTPRAI--QHLEGHIEEIADYLLDEV--SSKEKFDIVEDF 137 Query: 171 GCA-PCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGT 229 P VI ++ +D+ + NS + F Sbjct: 138 AGPLPIIVIAELLG---VPIQDRALFKKYSDDLVSGAENNS------------DEAFAKM 182 Query: 230 HNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVG 289 K + V + Y +E + E Q N ++ + L++ E + + E ++G Sbjct: 183 MQKRNEGVIFLQGYFKEIIAERQ-----QNKQEDLISLLLEAEIDGE----HLTEEEVLG 233 Query: 290 TVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTD 349 L VAG ETT+ + G+ + + +V +V+ +I V Sbjct: 234 FCILLLVAGNETTTNLITNGVRYMTEDVDVQNEVRRDISLV------------------P 275 Query: 350 AVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDP 409 +V E RY + + D + I +G +++ S D +F P+ F Sbjct: 276 NLVEETLRYYPPIQ-AIGRIAAEDVELGECKIKRGQQVISWAASANRDSAKFEWPDTF-- 332 Query: 410 GHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDL-KNLN 468 +K++ + F G C G LARME + T +L+ V + Sbjct: 333 -------VVHRKTNPHVSFGFGIHFCLGAPLARMEGKIAFTKLLEKGGFSKVQNQSLKPI 385 Query: 469 TTAVTKGIVSLPPSYQICF 487 + G+ Y+I F Sbjct: 386 DSPFVFGVKK----YEIAF 400 >4RM4-A nrPDB Length = 396 Score = 201 bits (512), Expect = 4e-52, Method: Composition-based stats. Identities = 83/445 (18%), Positives = 161/445 (36%), Gaps = 80/445 (17%) Query: 35 PLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEF 94 P P +M KD SF ++ V++V+ Y+ VK+ + + E F Sbjct: 26 PFPWYESM----RKDAPVSFDEENQ----VWSVFL----------YDDVKKV-VGDKELF 66 Query: 95 SGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVE 154 S P Q + G II+ + + +IR M + E R+QE L++ Sbjct: 67 S--SCMP-QQTSSIGNSIINMDPPKHTKIRSVVNKAFTPRVM--KQWEPRIQEITDELIQ 121 Query: 155 ELRKTKASPCDPTFILGCA-PCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWI 213 + + S D P VI ++ + + + ++++P Sbjct: 122 KFQ--GRSEFDLVHDFSYPLPVIVISELLGVPSAHMEQFKAWSDL--------LVSTPKD 171 Query: 214 QVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQ 273 + ++ + K ++ ++E + N P I L++ E+ Sbjct: 172 KSEEAEKAFLE-------ERDKCEEELAAFFAGIIEEKR-----NKPEQDIISILVEAEE 219 Query: 274 EKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGR 333 + + + E L+ L VAG ETT+ + + +L+ P V +++ + Sbjct: 220 TGE----KLSGEELIPFCTLLLVAGNETTTNLISNAMYSILETPGVYEELRSHPE----- 270 Query: 334 HRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTS 393 V E R+ P + DT+ +LI +G ++A + S Sbjct: 271 -------------LMPQAVEEALRFRAPAPV-LRRIAKRDTEIGGHLIKEGDMVLAFVAS 316 Query: 394 VLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTIL 453 D+ +F P++FD + + F G C G LAR+E + LT+++ Sbjct: 317 ANRDEAKFDRPHMFDIRR---------HPNPHIAFGHGIHFCLGAPLARLEANIALTSLI 367 Query: 454 QNFNLKSVDDLKNLNTTAVTKGIVS 478 F + + +V G+ S Sbjct: 368 SAFPHMECVSITPI-ENSVIYGLKS 391 >3MZS-A nrPDB Length = 486 Score = 201 bits (512), Expect = 5e-52, Method: Composition-based stats. Identities = 84/448 (18%), Positives = 161/448 (35%), Gaps = 35/448 (7%) Query: 31 PGPTPLPIIGNML-QIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALID 89 PG + + + + I + YGP++ G V E V Sbjct: 16 PGDNGWLNLYHFWREKGSQRIHFRHIENFQKYGPIYREKLGNLESVYIIHPEDVAHLFKF 75 Query: 90 NG---EEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQ 146 G E + + K +G++ WK+ R L T ++ + Sbjct: 76 EGSYPERYDIPPWLAYHRYYQKPIGVLFKKSGTWKKDR-VVLNTEVMAPEAIKNFIPLLN 134 Query: 147 EEAHCLVEELRK---TKASP---CDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKR 200 + V L K + S D L I +V+F +R ++ ++ Sbjct: 135 PVSQDFVSLLHKRIKQQGSGKFVGDIKEDLFHFAFESITNVMFGERLGMLEETVNPEAQK 194 Query: 201 FNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKE---------H 251 F + + + + N P L F K ++ I K ++ Sbjct: 195 FIDAVYKMFHTSVPLLNVPPELYRLF---RTKTWRDHVAAWDTIFNKAEKYTEIFYQDLR 251 Query: 252 QASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLL 311 + + N P + C L + + +E++ + ++ G TTS TL++ L Sbjct: 252 RKTEFRNYPG-ILYCLL---------KSEKMLLEDVKANITEMLAGGVNTTSMTLQWHLY 301 Query: 312 LLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVT 371 + + V ++EE+ + + + +P A + E R + + Sbjct: 302 EMARSLNVQEMLREEVLNARRQAEGDISKMLQMVPLLKASIKETLRLHPIS-VTLQRYPE 360 Query: 372 TDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAG 431 +D ++YLIP T + + ++ D F +P+ FDP +L K+ + + F G Sbjct: 361 SDLVLQDYLIPAKTLVQVAIYAMGRDPAFFSSPDKFDPTRWLSKDKDLIH-FRNLGFGWG 419 Query: 432 KRICAGEGLARMELFLFLTTILQNFNLK 459 R C G +A +E+ LFL IL+NF ++ Sbjct: 420 VRQCVGRRIAELEMTLFLIHILENFKVE 447 >1Z8P-A nrPDB Length = 404 Score = 201 bits (510), Expect = 7e-52, Method: Composition-based stats. Identities = 80/451 (17%), Positives = 151/451 (33%), Gaps = 81/451 (17%) Query: 49 DICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNG-------------EEFS 95 D +++ + PV V F + GY+ K AL D EF Sbjct: 15 DWYRTYAELRET-APVTPVRFLGQDAWLVTGYDEAKAALSDLRLSSDPKKKYPGVEVEFP 73 Query: 96 GRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEE 155 P R + +S+ +R+ + ++ RV++ L++E Sbjct: 74 AYLGFPEDVRNYFATNMGTSDPPTHTRLRKLVSQEFTVRRV--EAMRPRVEQITAELLDE 131 Query: 156 LRKTKASPCDPTFILGCA-PCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQ 214 + + D P VIC ++ D+ + R++ +++ Sbjct: 132 VGDSG--VVDIVDRFAHPLPIKVICELLGV------DEKYRGEFGRWSSEILVMD----- 178 Query: 215 VCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQE 274 P + + ++I + V+ + P D + LI+++ + Sbjct: 179 ------------PERAEQRGQAAREVVNFILDLVERRR-----TEPGDDLLSALIRVQDD 221 Query: 275 KDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRH 334 D + + L L +AG E++ + + G LLL HP+ A V+ + Sbjct: 222 DDG---RLSADELTSIALVLLLAGFESSVSLIGIGTYLLLTHPDQLALVRRDPSA----- 273 Query: 335 RSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSV 394 V EI RY P + + IP+ +T++ + Sbjct: 274 -------------LPNAVEEILRYIAP-PETTTRFAAEEVEIGGVAIPQYSTVLVANGAA 319 Query: 395 LHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQ 454 D K+FP+P+ FD + + F G C G LA++E + L + Sbjct: 320 NRDPKQFPDPHRFDVTR---------DTRGHLSFGQGIHFCMGRPLAKLEGEVALRALFG 370 Query: 455 NF---NLKSVDDLKNLNTTAVTKGIVSLPPS 482 F +L D + + +GI LP Sbjct: 371 RFPALSLGIDADDVVWRRSLLLRGIDHLPVR 401 >6A7J-A nrPDB Length = 411 Score = 198 bits (502), Expect = 7e-51, Method: Composition-based stats. Identities = 68/390 (17%), Positives = 134/390 (34%), Gaps = 68/390 (17%) Query: 98 GNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELR 157 + P+ + G +++ +G + +R L + K + ++ + +E L Sbjct: 74 ADWPLIGLVNPGRSMLTVDGPDHRRLRTLVAQALTVKRVEK--LRAGIEALTNASLERLA 131 Query: 158 KT-KASPCDPTFILGCA-PCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQV 215 P D P NVI ++ D+ L + F + F P Sbjct: 132 ALPAGEPVDLKAEFAYPLPMNVISELMGVDAADHP-----RLKELFEKFFSTQTPP---- 182 Query: 216 CNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEK 275 +V + +A + + V+E +A NP D + LI ++ Sbjct: 183 ---------------EEVPQMMADLGTLFTKIVEEKKA-----NPGDDLTSALIAASEDG 222 Query: 276 DNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHR 335 D E ++ T+ + AG ETT + + + L HPE KV Sbjct: 223 D----HLTDEEILNTLQLIIAAGHETTISLIVNVVEALAIHPEQRKKVLS---------- 268 Query: 336 SPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVL 395 +P+ + V+ E R++ + T D + + ++PKG ++ ++ Sbjct: 269 -------GEIPW-EGVIEETLRWNTPTSHVLIRFATEDIEVGDKVLPKGEGLVVSFGALG 320 Query: 396 HDDKEF-PNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQ 454 D++++ P FD + + F G +C G L+R+E + L + + Sbjct: 321 RDEEQYGPTAGDFDATR---------TPNRHIAFGHGPHVCPGAALSRLEAGIALPALYE 371 Query: 455 NF---NLKSVDDLKNLNTTAVTKGIVSLPP 481 F +L + LP Sbjct: 372 RFPELDLAVPAAELRNKPIVTQNDLHDLPV 401 >2X2N-A nrPDB Length = 475 Score = 197 bits (501), Expect = 9e-51, Method: Composition-based stats. Identities = 74/452 (16%), Positives = 159/452 (35%), Gaps = 27/452 (5%) Query: 30 PPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALID 89 P P +PI+G+++Q + ++ +FT+ + + + Sbjct: 19 PVYPVTVPILGHIIQFGKSPLGFMQECKRQLKSGIFTINIVGKRVTIVGDPHEHSRFFLP 78 Query: 90 NGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEA 149 E S R + ++ R +E F L ++ +Q E Sbjct: 79 RNEVLSPREVYSFMVPVFGEGVAYAAPYPRMREQLNFLAEELTIAKF--QNFVPAIQHEV 136 Query: 150 HCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILN 209 + + N C +F +D +RF + + Sbjct: 137 RKFMAANWDKDEGEINLLEDCSTMIINTACQCLFG-----EDLRKRLDARRFAQLLAKME 191 Query: 210 SPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQAS--LDVNNPRDFIDCF 267 S I P+L+ + + + + E + +A+ ++ D + Sbjct: 192 SSLIPAAVFLPILLKLPLPQSARCHEARTELQKILSEIIIARKAAAVNKDSSTSDLLSGL 251 Query: 268 LIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHP---EVTAKVQ 324 L + ++ + ++ + G + AG T+S T + +L L+ HP + ++ Sbjct: 252 LSAVYRDG----TPMSLHEVCGMIVAAMFAGQHTSSITTTWSMLHLM-HPANVKHLEALR 306 Query: 325 EEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKG 384 +EI+ + + D MP+ + E R + + V D K +Y++PKG Sbjct: 307 KEIEEFPAQLNYNNVMD--EMPFAERCARESIRRDPPL-LMLMRKVMADVKVGSYVVPKG 363 Query: 385 TTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARME 444 I HD++ FP P +DP + K F+ F AG C G+ ++ Sbjct: 364 DIIACSPLLSHHDEEAFPEPRRWDPER------DEKVEGAFIGFGAGVHKCIGQKFGLLQ 417 Query: 445 LFLFLTTILQNFNLKSV-DDLKNLNTTAVTKG 475 + L T ++++ + + D++ + + + G Sbjct: 418 VKTILATAFRSYDFQLLRDEVPDPDYHTMVVG 449 >3WVS-A nrPDB Length = 401 Score = 197 bits (500), Expect = 1e-50, Method: Composition-based stats. Identities = 67/416 (16%), Positives = 136/416 (32%), Gaps = 67/416 (16%) Query: 73 PIVVFHGYEAVKEAL--IDNGEEFSGRGNSPISQRIT-KGLGIISSNGKRWKEIRRFSLT 129 P + YE + L S + P +++ + + + + +RR Sbjct: 48 PAWLATRYEDARLVLGDARFSRALSEEHDPPRARKFNAQAKSMFNMDAPDHTRLRRLISK 107 Query: 130 TLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNVICSVVFQKRFD 188 + + +V + AH L++++ K P D P VIC ++ Sbjct: 108 AFTIRRV--EELRPKVHDLAHRLIDDMLA-KGEPADLVADYALPIPTTVICELLG---VP 161 Query: 189 YKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKV 248 ++D+ + LN +V YI + Sbjct: 162 FEDREKFGRWTDAILSTSTLNPEEGRVKRM--------------------ELVGYIGGII 201 Query: 249 KEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRY 308 +A P D + +I+ + + + + L+ L +AG ETT++ + Sbjct: 202 AARRA-----QPADDLISGMIEAR----DVQDKLTEQELLDHCIGLLIAGHETTASQIPS 252 Query: 309 GLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDL-VPTGVP 367 + LL P+ ++ ++ + + + V E+ R+ L + P Sbjct: 253 FVYALLDQPQHWKRLLDDPELI------------------PSAVEELFRFVPLGSGSAAP 294 Query: 368 HAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMP 427 D + L+ G ++ L + D F +P S++ + Sbjct: 295 RYAREDIEVGGTLVRAGEPVLVALGAANRDGLRFEDPEEIKLDR---------PSNHHIG 345 Query: 428 FSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSY 483 F G C G LAR+EL L +L+ V + + +G S+P + Sbjct: 346 FGHGIHHCLGAPLARLELQEALRALLERLPTLKVAGDIAWKSEMMVRGPRSMPVGW 401 >6FSH-A nrPDB Length = 398 Score = 196 bits (499), Expect = 1e-50, Method: Composition-based stats. Identities = 72/418 (17%), Positives = 133/418 (31%), Gaps = 79/418 (18%) Query: 79 GYEAVKEALIDNGEEFSGRGNSP---------ISQRITKGLGIISSNGKRWKEIRRFSLT 129 G+ V++ L D+ ++FS R I + ++ + +R Sbjct: 47 GHAVVRQVLGDH-QQFSTRRRWDPRDEIGGKGIFRPRELVGNLMDYDPPEHTRLRHLLTP 105 Query: 130 TLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILG-CAPCNVICSVVFQKRFD 188 M R + R++E ++ + + P D + P V+C ++ R D Sbjct: 106 GFTQRRM--RRLAPRIEEIVTDRLDAM-EQAGPPADLIELFADEVPGAVLCELIGVPRDD 162 Query: 189 YKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKV 248 MK + + S R+ + +K Sbjct: 163 RD-----MFMKLCHGHLDASLS---------------------------QKRRAALGDKF 190 Query: 249 KEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRY 308 + ++ +D D F+ + E + E L G L +AG + S + Sbjct: 191 SRYLLAMIARERKDPGDGFIGSIVAEHGDT---ITDEELRGVCVQLMLAGDDNVSGMIGL 247 Query: 309 GLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPH 368 G+L LL+HPE A ++ + D V E+ RY + P Sbjct: 248 GVLALLRHPEQIAALRGDDQS------------------ADRAVDELIRYLTVPYAPTPR 289 Query: 369 AVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPF 428 D + +I +G T++ L D P+ + D + F Sbjct: 290 TAVEDVMVADQVIKEGETVLCSLPMANRDRALLPDADRLDVTR---------TPVPHVAF 340 Query: 429 SAGKRICAGEGLARMELFLFLTTILQNFN---LKSVDDLKNLNTTAVTKGIVSLPPSY 483 G C G L R++L + T + + F L T+ G+ SL ++ Sbjct: 341 GHGIHHCLGAALTRLQLRIAYTALWRRFPALQLADPAQEIMFRTSTPAYGLTSLLVAW 398 >6GMF-A nrPDB Length = 397 Score = 196 bits (499), Expect = 2e-50, Method: Composition-based stats. Identities = 74/425 (17%), Positives = 145/425 (34%), Gaps = 66/425 (15%) Query: 68 YFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQR-----ITKGLGIISSNGKRWKE 122 + Y+ V L D + FS RG + R + I+ + R + Sbjct: 31 RLQPQGFMAVGRYQDVARVLHD-AKGFSNRGWAASLPRGVKWDTSMPPSIVQVDPPRHGK 89 Query: 123 IRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVV 182 +R + + +E R+++ AH LV+ LR + P VI ++ Sbjct: 90 LRTLVTKAFTPRTVAQ--LEPRIRDIAHELVDGLRGKSTFEAT-VEVTVPMPMIVIAEML 146 Query: 183 FQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRS 242 + +F + ++ G ++ ++ + Sbjct: 147 GV--APERRADFKRWSDDMVGSLALVRV-----------------GNAAQLERSTQEFYA 187 Query: 243 YIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETT 302 Y E ++E + + L+ E + + + ++ L +AG ETT Sbjct: 188 YFSEVLEERRREPRE-----DLISQLLAAEVDGE----KLTAGEVLSFANTLLIAGNETT 238 Query: 303 STTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLV 362 ++ + L+ L HPE A Q + + AVV E+ RY Sbjct: 239 TSLIGNALVALTDHPEQLAAAQAD------------------LSLVPAVVEEVLRYESPA 280 Query: 363 PTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKS 422 + TD + + IP + ++ LL S D+ FP+P+ FD + + Sbjct: 281 QC-IFRQTMTDVEIGDERIPARSVVLPLLASANRDESRFPDPDRFDI---------HRDT 330 Query: 423 DYFMPFSAGKRICAGEGLARMELFLFLTTILQNF-NLKSVDDLKNLNTTAVTKGIVSLPP 481 + F C G LAR+E + L +L +++ V + + + + +LP Sbjct: 331 KGHLAFGLDIHFCIGAPLARLEAKVMLEVLLARLGDIQRVSQEVSWSPSFFIRSPSTLPL 390 Query: 482 SYQIC 486 + Sbjct: 391 RATVA 395 >3TYW-A nrPDB Length = 417 Score = 195 bits (496), Expect = 3e-50, Method: Composition-based stats. Identities = 81/420 (19%), Positives = 142/420 (33%), Gaps = 77/420 (18%) Query: 76 VFHGYEAVKEALIDNGEEFSGRGNSPISQRITKG--------LGIISSNGKRWKEIRRFS 127 V Y+ V+E L D R P + +G I ++ RR Sbjct: 57 VVTRYDDVRELLSDPRVSADIR--RPGFPALGEGEQEAGARFRPFIRTDAPEHTRYRRML 114 Query: 128 LTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAP-CNVICSVVFQKR 186 L + R++ VQ +++ + P D A +VIC ++ Sbjct: 115 LPAFTVRRV--RAMRPAVQARVDEILDGMLAAGG-PVDLVSAYANAVSTSVICELLG--- 168 Query: 187 FDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIRE 246 D F + R + + T +V + + + Sbjct: 169 IPRHDLEFFRDVTRISGSR---------------------NSTAEQVSEALGGLFGLLGG 207 Query: 247 KVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTL 306 V E + PRD + L+ N E L+ T+ AG ETT++ + Sbjct: 208 LVAERRE-----EPRDDLISKLVTDHLVPGN----VTTEQLLSTLGITINAGRETTTSMI 258 Query: 307 RYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGV 366 LLLL PE+ A+++++ D A V E+ R + + Sbjct: 259 ALSTLLLLDRPELPAELRKDPD------------------LMPAAVDELLRVLSVADSIP 300 Query: 367 PHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFM 426 D + +P ++ALL HD ++F +P D + ++ + Sbjct: 301 LRVAAEDIELSGRTVPADDGVIALLAGANHDPEQFDDPERVD---------FHRTDNHHV 351 Query: 427 PFSAGKRICAGEGLARMELFLFLTTILQN---FNLKSVDDLKNLNTTAVTKGIVSLPPSY 483 F G C G+ LAR+EL + L T+L+ L D + + T G+ L ++ Sbjct: 352 AFGYGVHQCVGQHLARLELEVALETLLRRVPTLRLAGERDQVVVKHDSATFGLEELMVTW 411 >4TX3-A nrPDB Length = 404 Score = 194 bits (494), Expect = 6e-50, Method: Composition-based stats. Identities = 73/418 (17%), Positives = 131/418 (31%), Gaps = 79/418 (18%) Query: 79 GYEAVKEALIDNGEEFSGRGNSP---------ISQRITKGLGIISSNGKRWKEIRRFSLT 129 G+ V++ L D+ + FS R + + ++ + +R Sbjct: 53 GHAVVRQVLGDH-KRFSTRRRFDRRDEIGGTGVFRPRELVGNLMDYDPPEHTRLRHLLTP 111 Query: 130 TLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILG-CAPCNVICSVVFQKRFD 188 M R + R++E ++ + + P D + P V+C ++ R D Sbjct: 112 GFTQRRM--RRLAPRIEEIVTDRLDAM-EQAGPPADLIELFADEVPGAVLCELIGVPRDD 168 Query: 189 YKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKV 248 FL L R + A R+ E Sbjct: 169 --QAMFLQLCHRHLD------------------------------ASLSARKRAAAGEAF 196 Query: 249 KEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRY 308 + ++ +D D F+ + E + E L G L +AG + S + Sbjct: 197 ARYLVAMMARERKDPGDGFIGSIVAEHGDT---ITDEELRGVCVQLMLAGDDNVSGMIGL 253 Query: 309 GLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPH 368 G+L LL+HPE A ++ + D V E+ RY + P Sbjct: 254 GVLALLRHPEQIAALRGDDQS------------------ADRAVDELIRYLTVPYAPTPR 295 Query: 369 AVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPF 428 D + +I +G T++ L D P+ + D + F Sbjct: 296 TAVEDVMVADQVIKEGETVLCSLPMANRDRALLPDADRLDVTR---------TPVPHVAF 346 Query: 429 SAGKRICAGEGLARMELFLFLTTILQNFN---LKSVDDLKNLNTTAVTKGIVSLPPSY 483 G C G L R++L + T + + F L T+ G+ SL ++ Sbjct: 347 GHGIHHCLGAALTRLQLRIAYTALWRRFPALQLADPAQEIMFRTSTPAYGLTSLLVAW 404 >5FOI-A nrPDB Length = 408 Score = 194 bits (492), Expect = 8e-50, Method: Composition-based stats. Identities = 76/418 (18%), Positives = 144/418 (34%), Gaps = 73/418 (17%) Query: 73 PIVVFHGYEAVKEALIDNGE--EFSGRGNSPISQRITKGL-GIISSNGKRWKEIRRFSLT 129 P + YE V+ L+D + + + + G ++ + +RR ++ Sbjct: 57 PTWLVSRYEHVRALLVDPRVTVDPTRQPRLSEADGDGDGFRSMLMLDPPEHTRLRRMFIS 116 Query: 130 TLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNVICSVVFQKRFD 188 + ++ +++ +++ L + P D L VIC ++ Sbjct: 117 AFSVRQV--ETMRPEIEKIVDGILDRLLALE-PPVDILTHLALPMSTQVICHLLG---VP 170 Query: 189 YKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKV 248 Y+D+ F F E + + P ++ + + Y+ V Sbjct: 171 YEDREF------FQERSELASRP-----------------NDDRSMPALIELVEYLDGLV 207 Query: 249 KEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRY 308 + A D L+ + K E + LV L AG ET++ + Sbjct: 208 RTKTAHP---------DTGLLGTAVTERLLKGEITHQELVNNAVLLLAAGHETSANQVTL 258 Query: 309 GLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPH 368 +L LL+HPE A+++E+ + V E+ RY + G+ Sbjct: 259 SVLTLLRHPETAAELREQPE------------------LMPNAVDELLRYHSIAD-GLRR 299 Query: 369 AVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPF 428 A T D ++ I G ++ LL+S HD F FD + + + F Sbjct: 300 AATADIVLGDHTIRAGDGLIILLSSANHDGNTFGAEATFDIHR---------PARHHVAF 350 Query: 429 SAGKRICAGEGLARMELFLFLTTILQN---FNLKSVDDLKNLNTTAVTKGIVSLPPSY 483 G C G+ LAR+E+ + L + + L D + + GI L + Sbjct: 351 GYGPHQCLGQNLARLEMEVTLGKLFRRVPALRLAQEPDALRVRQGSPIFGIDELLVEW 408 >4KPA-A nrPDB Length = 494 Score = 193 bits (491), Expect = 1e-49, Method: Composition-based stats. Identities = 86/437 (19%), Positives = 156/437 (35%), Gaps = 26/437 (5%) Query: 31 PGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDN 90 P P + N+ ++ ++ + G +F +KEA D Sbjct: 30 PQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEA-CDE 88 Query: 91 GEEFSGRGNSPISQRITKGLGIISS--NGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEE 148 + R G G+ +S + K WK+ L + + + + Sbjct: 89 SRFDKNLSQALKFVRDFAGDGLFTSWTHEKNWKKAHNILLPSFSQ--QAMKGYHAMMVDI 146 Query: 149 AHCLVEELRKTKASP-CDPTFILGCAPCNVICSVVFQKRFD--YKDQNFLTLMKRFNENF 205 A LV++ + A + + + I F RF+ Y+DQ + Sbjct: 147 AVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALD 206 Query: 206 RILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFID 265 +N ++ + + +++ + + + + + +AS + D Sbjct: 207 EAMNKLQRANPDD-----PAYDENKRQFQEDIKVMNDLVDKIIADRKAS------GEQSD 255 Query: 266 CFLIKMEQEKDNQKSE-FNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQ 324 L M KD + E + EN+ + +AG ETTS L + L L+K+P V K Sbjct: 256 DLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAA 315 Query: 325 EEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRN-YLIPK 383 EE V+ P + + Y V++E R P DT Y + K Sbjct: 316 EEAARVL-VDPVPSYKQVKQLKYVGMVLNEALRLWPTAP-AFSLYAKEDTVLGGEYPLEK 373 Query: 384 GTTIMALLTSVLHDDKEFPNP-NIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLAR 442 G +M L+ + D + + F P F +N + F PF G+R C G+ A Sbjct: 374 GDELMVLIPQLHRDKTIWGDDVEEFRPERF--ENPSAIPQHAFKPFGNGQRACIGQQFAL 431 Query: 443 MELFLFLTTILQNFNLK 459 E L L +L++F+ + Sbjct: 432 HEATLVLGMMLKHFDFE 448 >2WM5-A nrPDB Length = 435 Score = 192 bits (488), Expect = 3e-49, Method: Composition-based stats. Identities = 72/414 (17%), Positives = 140/414 (33%), Gaps = 65/414 (15%) Query: 77 FHGYEAVKEALIDNGEEFSGRGNSPISQRITKG----LGIISSNGKRWKEIRRFSLTTLR 132 Y+ V A + + FS N I+ + + +I + R + +R Sbjct: 79 LTKYDDVFYA-SRHPDIFSSYPNITINDQTPELAEYFGSMIVLDDPRHQRLRSIVSRAFT 137 Query: 133 NFGMGKRSIEDRVQEEAHCLVEEL-RKTKASPCDPTFILGCA-PCNVICSVVFQKRFDYK 190 + + IE V++ AH LV + D L P +IC ++ + D+ Sbjct: 138 PKVVAR--IEAAVRDRAHRLVSSMIANNPDRQADLVSELAGPLPLQIICDMMGIPKADH- 194 Query: 191 DQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKE 250 + F+ IL + +F ++ ++ A +Y ++ Sbjct: 195 -------QRIFHWTNVILGFGDPDLATDF-----------DEFMQVSADIGAYATALAED 236 Query: 251 HQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGL 310 + + D + L++ E + + + + L VAG ETT + +G+ Sbjct: 237 RRVNHH-----DDLTSSLVEAEVDGE----RLSSREIASFFILLVVAGNETTRNAITHGV 287 Query: 311 LLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAV 370 L L ++PE + + D V EI R++ V + + Sbjct: 288 LALSRYPEQRDRWWSDFDG-----------------LAPTAVEEIVRWASPV-VYMRRTL 329 Query: 371 TTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPF-S 429 T D + R + G + S D+ +F +P FD + + F Sbjct: 330 TQDIELRGTKMAAGDKVSLWYCSANRDESKFADPWTFDLAR---------NPNPHLGFGG 380 Query: 430 AGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSY 483 G C G LAR E+ + + + + + GI +LP ++ Sbjct: 381 GGAHFCLGANLARREIRVAFDELRRQMPDVVATEEPARLLSQFIHGIKTLPVTW 434 >1UED-A nrPDB Length = 406 Score = 192 bits (487), Expect = 4e-49, Method: Composition-based stats. Identities = 75/439 (17%), Positives = 146/439 (33%), Gaps = 80/439 (18%) Query: 59 KVYGPVFTV------YFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQ-----RIT 107 + +GP+ + G + + HGYE V+ L D+ E F+ R S+ Sbjct: 34 RAHGPLVRIVGESSTQLGRDFVWQAHGYEVVRRILGDH-EHFTTRPQFTQSKSGAHVEAQ 92 Query: 108 KGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPT 167 I + + +R+ + R +E +Q ++ L D Sbjct: 93 FVGQISTYDPPEHTRLRKMLTPEFTVRRI--RRMEPAIQSLIDDRLDLLEAE-GPSADLQ 149 Query: 168 FILGCAP-CNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCF 226 + + +C ++ R D + F+ ++R D Sbjct: 150 GLFADPVGAHALCELLGIPRDD--QREFVRRIRRN---------------------ADLS 186 Query: 227 PGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIEN 286 G + + A R Y+ + +A +P D + +++ + E Sbjct: 187 RGLKARAADSAAFNR-YLDNLLARQRA-----DPDDGLLGMIVR------DHGDNVTDEE 234 Query: 287 LVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMP 346 L G L + G ET + + +G+L LL +P + E + Sbjct: 235 LKGLCTALILGGVETVAGMIGFGVLALLDNPGQIELLFESPEK----------------- 277 Query: 347 YTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNI 406 + VV+E+ RY V P D LI G ++ + D+ P+P++ Sbjct: 278 -AERVVNELVRYLSPVQAPNPRLAIKDVVIDGQLIKAGDYVLCSILMANRDEALTPDPDV 336 Query: 407 FDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFN-LKSVDDLK 465 D + + + F G C G LAR L + T+ + F L+ ++ Sbjct: 337 LD---------ANRAAVSDVGFGHGIHYCVGAALARSMLRMAYQTLWRRFPGLRLAVPIE 387 Query: 466 NLNT-TAVTKGIVSLPPSY 483 + +A +P ++ Sbjct: 388 EVKYRSAFVDCPDQVPVTW 406 >6F0B-A nrPDB Length = 395 Score = 191 bits (486), Expect = 4e-49, Method: Composition-based stats. Identities = 82/421 (19%), Positives = 138/421 (32%), Gaps = 72/421 (17%) Query: 72 NPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWK----EIRRFS 127 P VF GYE V+ L FS P +T L ++ + + RR Sbjct: 38 TPAHVFSGYEDVRTVL--QDRRFSSDSRRPNFTELTPTLQSQAAAPPFVRTDNPDHRRLR 95 Query: 128 LTTLRNF-GMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKR 186 T R F + ++E +++ L +T A P D + VF+ Sbjct: 96 GTIAREFLPKHIELLRPAIREIVQGVLDGLAET-APPQDMLEAFAVPVA---SATVFRLL 151 Query: 187 -FDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIR 245 +D+ LT R + + F L + G Sbjct: 152 GIPAEDRALLT---RCVKGVVSAVGSEDEGAEVFRTLGEYIGGL---------------- 192 Query: 246 EKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTT 305 V +P + + LI+ Q+ + +G + L V G +TT++T Sbjct: 193 -----------VQDPSELPEDSLIRRLVTGPYQEKQLTFHETIGVILMLIVGGYDTTAST 241 Query: 306 LRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTG 365 + L+ PE + V E + + +V E+ RY + G Sbjct: 242 ISLSLVSYALQPEKFSVVHEHPERI------------------PLLVEELLRYHTVSQLG 283 Query: 366 VPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYF 425 + T D + + G ++A L D+ FPNP+ D S Sbjct: 284 LGRIATEDVEVGGVTVRAGQMVVAALPLANRDESVFPNPDELDFDR---------PSVPH 334 Query: 426 MPFSAGKRICAGEGLARMELFLFLTTILQNF---NLKSVDDLKNLNTTAVTKGIVSLPPS 482 + F G C G+ LAR+EL + +++ L + T GI LP + Sbjct: 335 VGFGYGPHQCVGQALARVELQEAIPAVIRRLPGMRLACALEDLPFRHDMATYGIHELPMT 394 Query: 483 Y 483 + Sbjct: 395 W 395 >2WIO-A nrPDB Length = 431 Score = 191 bits (486), Expect = 5e-49, Method: Composition-based stats. Identities = 72/422 (17%), Positives = 131/422 (31%), Gaps = 65/422 (15%) Query: 63 PVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKE 122 PV+ +G + + V+ L D FS I I + + Sbjct: 62 PVWQDRYG---VWHVFRHADVQTVLRDTA-TFSSDPTRVIEGASPTPGMIHEIDPPEHRA 117 Query: 123 IRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNVICSV 181 +R+ + + +E R+++ L+ D +L P ++ + Sbjct: 118 LRKVVSSAFTPRTISD--LEPRIRDVTRSLL----ADAGESFDLVDVLAFPLPVTIVAEL 171 Query: 182 VFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTR 241 + D++ W + + P ++ + Sbjct: 172 LGLPPMDHEQ-----------------FGDWSGALVDIQMDDPTDPALAERIADVLNPLT 214 Query: 242 SYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTET 301 +Y++ + E +A +P D + L+ E + + E L +AG T Sbjct: 215 AYLKARCAERRA-----DPGDDLISRLVLAEVDGRA----LDDEEAANFSTALLLAGHIT 265 Query: 302 TSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDL 361 T+ L + L +HP E+ + A+V E+ RY Sbjct: 266 TTVLLGNIVRTLDEHPAHWDAAAEDPGRI------------------PAIVEEVLRYRPP 307 Query: 362 VPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKK 421 P + T T+ IP + + S D +P+ FDP Sbjct: 308 FPQ-MQRTTTKATEVAGVPIPADVMVNTWVLSANRDSDAHDDPDRFDPSR-------KSG 359 Query: 422 SDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVD-DLKNLNT-TAVTKGIVSL 479 + F G C G LAR+E + L I+ F +VD D + L + G L Sbjct: 360 GAAQLSFGHGVHFCLGAPLARLENRVALEEIIARFGRLTVDRDDERLRHFEQIVLGTRHL 419 Query: 480 PP 481 P Sbjct: 420 PV 421 >6GK6-A nrPDB Length = 411 Score = 191 bits (485), Expect = 6e-49, Method: Composition-based stats. Identities = 81/414 (19%), Positives = 138/414 (33%), Gaps = 70/414 (16%) Query: 76 VFHGYEAVKEALIDNGEEFSGRGNSPISQRITKG-LGIISSNGKRWKEIRRFSLTTLRNF 134 + +++ + R P+S R T ++ ++ +R Sbjct: 56 LLKDPRLIRDF--RKLPDEVRRRYFPLSDRTTFMDQHMLDADPPDHTRLRAIVQRAFSP- 112 Query: 135 GMGKRSIEDRVQEEAHCLVEEL--RKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQ 192 + R+QE A L++ + R+ D F L P VI ++ D Sbjct: 113 -RMMEGLRPRIQEIADGLIDAVIDRRRMELIADFAFPL---PTAVIAELLGLPVEDRG-- 166 Query: 193 NFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQ 252 RF +IL P F V++ A +Y R + Sbjct: 167 -------RFRRWTKIL---------LAPAKDREFVERAQPVVEEFA---AYFRALADARR 207 Query: 253 ASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLL 312 + PRD + L+ E+ Q+ + + L V L VAG ETT + G+LL Sbjct: 208 KA-----PRDDLISGLLLAEE----QEHKLSPAELSSMVFLLLVAGHETTVHLIASGMLL 258 Query: 313 LLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTT 372 LL HP ++ E+ V + V E R Sbjct: 259 LLSHPAERRRLDEDPGLV------------------GSAVEEALRCEGPAELSTIRWSLE 300 Query: 373 DTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGK 432 D + +P G + A L + D + FP+P+ FD G + + F G Sbjct: 301 DIELFGARVPAGEGVAAGLLAANRDPQHFPDPDRFDIGR---------SPNRHIGFGGGI 351 Query: 433 RICAGEGLARMELFLFLTTILQNF---NLKSVDDLKNLNTTAVTKGIVSLPPSY 483 C G LAR+E + +T+L+ L + + +G ++P + Sbjct: 352 HFCLGAMLARIEAAIAFSTLLRRLPRIELATSTRDIVWSEWPTIRGPAAVPVVF 405 >6A7I-A nrPDB Length = 411 Score = 190 bits (483), Expect = 1e-48, Method: Composition-based stats. Identities = 69/389 (17%), Positives = 132/389 (33%), Gaps = 68/389 (17%) Query: 99 NSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRK 158 + P+ G +++ +G + +R L + + ++ + +E+L Sbjct: 75 DWPLIGLANPGRSMLTVDGADHRRLRTLVAQALTVKRV--ERLRAGIEALTNASLEKLAA 132 Query: 159 T-KASPCDPTFILGCA-PCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVC 216 P D P NVI ++ D+ L + F + F P Sbjct: 133 LPAGEPVDLKAEFAYPLPMNVISELMGVDAADHP-----RLKELFEKFFSTQTPP----- 182 Query: 217 NNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKD 276 +V + +A + + V + NP D + LI + D Sbjct: 183 --------------EEVPQMMADLGALFTKIVDAKR-----TNPGDDLTSALIAASENGD 223 Query: 277 NQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRS 336 E +V T+ + AG ETT + + + L HPE KV ++ IG Sbjct: 224 ----HLTDEEIVNTLQLIIAAGHETTISLIVNVVEALQTHPEQRKKV---LNGEIG---- 272 Query: 337 PCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLH 396 D V+ E R++ + T D + + ++PKG ++ ++ Sbjct: 273 -----------WDGVIEETLRWNTPTSHVLIRFATEDIEVGDKILPKGEGLIISFGALGR 321 Query: 397 DDKEF-PNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQN 455 D++++ P FD + + F G +C G L+R+E + L + + Sbjct: 322 DEEQYGPTAGEFDATR---------TPNRHIAFGHGPHVCPGAALSRLEAGIALPALYER 372 Query: 456 F-NLKSVDDLKNLNTTAVT--KGIVSLPP 481 F L +L + + LP Sbjct: 373 FPELDLAVPASDLRNKPIVTQNDLHELPV 401 >1EHE-A nrPDB Length = 403 Score = 190 bits (482), Expect = 1e-48, Method: Composition-based stats. Identities = 66/379 (17%), Positives = 116/379 (30%), Gaps = 64/379 (16%) Query: 110 LGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRK--TKASPCDPT 167 + + R T ++++ +Q L+E++++ P D Sbjct: 84 PTFVDMDPPEHMHQRSMVEPTFTP--EAVKNLQPYIQRTVDDLLEQMKQKGCANGPVDLV 141 Query: 168 FILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFP 227 + I + + D +LT N Sbjct: 142 KEFALPVPSYIIYTLLG--VPFNDLEYLTQQNAIRTNGS--------------------- 178 Query: 228 GTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENL 287 T + Y+ V++ P+D I L + + N + + Sbjct: 179 STAREASAANQELLDYLAILVEQRLV-----EPKDDIISKLCTEQVKPGN----IDKSDA 229 Query: 288 VGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPY 347 V L VAG T + G+ L +HP+ A+++ Sbjct: 230 VQIAFLLLVAGNATMVNMIALGVATLAQHPDQLAQLKANPS------------------L 271 Query: 348 TDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIF 407 V E+ RY + D + L+ I+A S D++ F NP+ F Sbjct: 272 APQFVEELCRYHTASALAIKRTAKEDVMIGDKLVRANEGIIASNQSANRDEEVFENPDEF 331 Query: 408 DPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF-NLKSVDDLKN 466 + + F G C E LA+ EL +T+ Q F +LK L Sbjct: 332 NMNRKWPPQDP-------LGFGFGDHRCIAEHLAKAELTTVFSTLYQKFPDLKVAVPLGK 384 Query: 467 LNTTAVTK--GIVSLPPSY 483 +N T + + GIV LP + Sbjct: 385 INYTPLNRDVGIVDLPVIF 403 >5NWS-A nrPDB Length = 435 Score = 189 bits (481), Expect = 2e-48, Method: Composition-based stats. Identities = 79/457 (17%), Positives = 149/457 (32%), Gaps = 89/457 (19%) Query: 49 DICKSFTNFSKVYGPVFTVYF-GMNPIVVFHGYEAVKEAL-----------------IDN 90 D + + GPV F P+ Y+ V+ L D Sbjct: 35 DPFTGYGRLRER-GPVVRGRFVDGTPVWFVTRYDDVRAVLRDPRFVNTPSPVPGEGGADP 93 Query: 91 GEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAH 150 E N P R+ I+ S+ +RR + + ++ A Sbjct: 94 REGMMDLLNVPEPLRVYLLGSILDSDPPDHPRLRRLVTRAFAARRIL--GLRPGIERIAD 151 Query: 151 CLVEEL--RKTKASPCDPTFILGCA-PCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRI 207 L+ EL R+ + D VIC +V D L + + Sbjct: 152 RLLAELPRREEEDGTVDLLEHFAYPLSITVICELVGIPATD--------LERWREWGGDL 203 Query: 208 LNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCF 267 ++ ++ ++FP++ID Y +++ +A+ D Sbjct: 204 VSMRPERLRHSFPVMID------------------YCHRLIEQRRAA--------LTDDL 237 Query: 268 LIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEI 327 L ++ + +D+ + V + L +AG ET++ + G LL HP A ++++ Sbjct: 238 LSELIRAQDDDGGRLSDIETVTMILTLVLAGHETSAHLIGNGTAALLTHPGQWALLRKDP 297 Query: 328 DHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTI 387 VHE+ R+ V T D + + +G + Sbjct: 298 A------------------LLPRAVHELMRWCGSVHVARLRYATEDLELAGTPVARGDAV 339 Query: 388 MALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFL 447 +L S D + + +P+ D + +++ + F G C G LAR E + Sbjct: 340 QLVLVSANFDPRHYSDPDRLDITRHQE-----GQAENHVGFGHGIHYCLGATLARQEGEV 394 Query: 448 FLTTILQNF-NLKSVDDLKNLNTTAVTKGIVSLPPSY 483 L +L+ + +L D + LP S+ Sbjct: 395 ALARLLETYPDLALADGDPEVRRAR-------LPGSW 424 >1LG9-A nrPDB Length = 398 Score = 189 bits (480), Expect = 3e-48, Method: Composition-based stats. Identities = 66/421 (15%), Positives = 133/421 (31%), Gaps = 79/421 (18%) Query: 76 VFHGYEAVKEALIDNGEEFSGRGNSP---------ISQRITKGLGIISSNGKRWKEIRRF 126 + + V++ + D+ ++FS R I + ++ + +RR Sbjct: 44 MATAHAVVRQVMGDH-QQFSTRRRWDPRDEIGGKGIFRPRELVGNLMDYDPPEHTRLRRK 102 Query: 127 SLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCD-PTFILGCAPCNVICSVVFQK 185 M + + +++ + ++E+ + SP D F+ P V+C +V Sbjct: 103 LTPGFTLRKM--QRMAPYIEQIVNDRLDEMER-AGSPADLIAFVADKVPGAVLCELVGVP 159 Query: 186 RFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIR 245 R D MK + + S R+ + Sbjct: 160 RDDRD-----MFMKLCHGHLDASLS---------------------------QKRRAALG 187 Query: 246 EKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTT 305 +K + ++ ++ + + + E + + E L G + +AG + S Sbjct: 188 DKFSRYLLAMIARERKEPGEGMIGAVVAEYGD---DATDEELRGFCVQVMLAGDDNISGM 244 Query: 306 LRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTG 365 + G+L +L+HPE + + V E+ RY + + Sbjct: 245 IGLGVLAMLRHPEQIDAFRGDEQS------------------AQRAVDELIRYLTVPYSP 286 Query: 366 VPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYF 425 P D I KG +++ L + D P+ + D + Sbjct: 287 TPRIAREDLTLAGQEIKKGDSVICSLPAANRDPALAPDVDRLDVTR---------EPIPH 337 Query: 426 MPFSAGKRICAGEGLARMELFLFLTTILQNF---NLKSVDDLKNLNTTAVTKGIVSLPPS 482 + F G C G LAR+EL T + + F L T G+ L + Sbjct: 338 VAFGHGVHHCLGAALARLELRTVFTELWRRFPALRLADPAQDTEFRLTTPAYGLTELMVA 397 Query: 483 Y 483 + Sbjct: 398 W 398 >6B11-A nrPDB Length = 440 Score = 188 bits (478), Expect = 4e-48, Method: Composition-based stats. Identities = 76/421 (18%), Positives = 148/421 (35%), Gaps = 78/421 (18%) Query: 73 PIVVFHGYEAVKEALIDNGEEFSGRG-----NSPISQRITKGLGIISSNGKRWKEIRRFS 127 P+ + + V+ L D S SP +++ + +R Sbjct: 88 PVWLISRQDHVRALLAD--PRVSIHPAKLPRLSPSDGEAEASRSLLTLDPPDHGALRGHF 145 Query: 128 LTTLRNFGMGK-RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNVICSVVFQK 185 + FG+ + R + V++ L+++L + D VIC ++ Sbjct: 146 ---IPEFGLRRVRELRPSVEQIVTGLLDDLTA-RGDEADLLADFALPMATQVICRLL--- 198 Query: 186 RFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIR 245 Y+D+++ +R + R P + L+ + R Y+ Sbjct: 199 DIPYEDRDYF--QERTEQATR--------------------PAAGEEALEALLELRDYLD 236 Query: 246 EKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTT 305 + R+ D L M + + + +++ L AG ETT++ Sbjct: 237 RLISGK-------TGRESGDGMLGSMVAQA--RGGGLSHADVLDNAVLLLAAGHETTASM 287 Query: 306 LRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTG 365 + +L+LL+HP ++ + G V E+ RY + G Sbjct: 288 VTMSVLVLLQHPTAWRELTVNPGLLPG------------------AVDELLRYLSIAD-G 328 Query: 366 VPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYF 425 + + T D + + I G ++ LL + D+ F P FD + + Sbjct: 329 LRRSATADIEIDGHTIRAGDGLVFLLAAANRDEAVFSEPEAFDI---------HRSARRH 379 Query: 426 MPFSAGKRICAGEGLARMELFLFLTTILQNFN-LKSVDDLK--NLNTTAVTKGIVSLPPS 482 + F G C G+ LARMEL + L +L+ L+ D+ L + + G+ LP + Sbjct: 380 VAFGYGPHQCLGQNLARMELEVALGAVLERLPALRPTTDVAGLRLKSDSAVFGVYELPVA 439 Query: 483 Y 483 + Sbjct: 440 W 440 >5XW2-A nrPDB Length = 419 Score = 187 bits (474), Expect = 1e-47, Method: Composition-based stats. Identities = 76/409 (18%), Positives = 133/409 (32%), Gaps = 57/409 (13%) Query: 77 FHGYEAVKEALIDNGEEFSG--RGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNF 134 +GY E L D G S R + ++ ++ +E+R+ Sbjct: 57 VYGYAEAIEVLGDPGTFSSHMSRLLPMGADEAFTEGDLLQTDPPDHRELRKLVSHAFTPK 116 Query: 135 GMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNVICSVVFQKRFDYKDQN 193 + +E R+ L++ + D L P V+ ++ D++ Sbjct: 117 VVA--ELEPRITALTQELLDAVAD--RDTFDLMTALAYPLPVTVVAELL---SIPSADRH 169 Query: 194 FLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQA 253 E L ++ P ++ + + E ++EH A Sbjct: 170 LFE--GWMTEIVHSLGDVS----------MEDAPEDQERIFEAGMAPMRKMLEYLREHAA 217 Query: 254 SLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLL 313 PR + LI+ E + ++V L +AG TT+ + +L L Sbjct: 218 ECR-RRPRGDLMGKLIEAEVDG----RRLTDNHIVNFAKMLLIAGYLTTTMLIGNTVLCL 272 Query: 314 LKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTD 373 +PE A+V+ DRS +P ++ E R+ V A T D Sbjct: 273 DSYPEQAARVRA---------------DRSLIP---GLLEESMRFLSPV-AATYRATTRD 313 Query: 374 TKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKR 433 + + +M + D ++F P +FD + + F G Sbjct: 314 VEVAGQRLSADQMVMVWFGAANRDARQFAEPELFDMTR---------GPNPHLGFGRGIH 364 Query: 434 ICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAV--TKGIVSLP 480 C G LARME + L +L F D + T G+ SLP Sbjct: 365 FCLGGPLARMEGRVALDHLLDRFPELYTDPERPPTFMPGFDTTGVSSLP 413 >6M7L-A nrPDB Length = 404 Score = 186 bits (473), Expect = 1e-47, Method: Composition-based stats. Identities = 84/450 (18%), Positives = 149/450 (33%), Gaps = 81/450 (18%) Query: 42 MLQIDVKDICKSFTNFSKVYGPVFTVYF--GMNPIVVFHGYEAVKEALIDNGEEFSGRGN 99 +L + + + GP+ + G GY+ V+E L + G Sbjct: 28 VLHLRDRLDLAAELKLLCERGPLVRIPLEDGSAVHWFALGYDVVREVLGSEKFDKRVIGT 87 Query: 100 SPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKT 159 Q + ++ + +RR M +++E RVQ ++ + T Sbjct: 88 HFNHQEMALPGNLLQLDPPEHTRLRRMVAPAYSVRRM--QALEPRVQAIVDDHLDTMAST 145 Query: 160 KASPCD-PTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNN 218 P + + G V C + D + LT + Sbjct: 146 -GPPVEFLREVAGPMAARVACEFLGIPLDDRGELIRLTAHR------------------- 185 Query: 219 FPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQ 278 G + + N +Y+RE + RD D L + ++ Sbjct: 186 ---------GGKRRRVLNGHAYLAYMRELAARLR--------RDPGDGMLGMVARD---H 225 Query: 279 KSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPC 338 ++ + E L G A + + E T + L G LLLL+HPE A ++E + Sbjct: 226 GADISDEELAGLCAVVMNSSVEQTESCLAAGTLLLLEHPEQFALLRERPE---------- 275 Query: 339 MQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLH-D 397 + V EI RY + P T D + +I KG + L + D Sbjct: 276 --------LGEQAVEEIVRYLSVFEGLDPRTATEDVEIGGQVIKKGEAVFCSLLAANRAD 327 Query: 398 DKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF- 456 + FD K + F G C G LARMEL + TT++ F Sbjct: 328 PAL----DGFDITR---------KESRHVAFGHGIHHCLGAPLARMELRIAFTTLVSRFP 374 Query: 457 NLKSVDDLKNLN---TTAVTKGIVSLPPSY 483 +L++ + + ++ ++ LP ++ Sbjct: 375 SLRTAVPAEEIRFRPPSSNVFTLLELPLTW 404 >5LIE-A nrPDB Length = 414 Score = 186 bits (472), Expect = 2e-47, Method: Composition-based stats. Identities = 67/383 (17%), Positives = 119/383 (31%), Gaps = 62/383 (16%) Query: 98 GNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELR 157 + P++ ++ + + R IRR + L R +ED ++ A L++ + Sbjct: 86 QDLPVAGQVLNMM-----DDPRHTRIRRLVSSGLTP--RMIRRVEDDLRRRARGLLDGVE 138 Query: 158 KTKASPCDPTFILGC-APCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVC 216 +P D + P +IC ++ D L + F S Sbjct: 139 P--GAPFDFVVEIAAELPMQMICILLGVPETDRH-----WLFEAVEPGFDFRGS------ 185 Query: 217 NNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKD 276 V + +Y E + +A P D + ++ D Sbjct: 186 -------RRATMPRLNVEDAGSRLYTYALELIAGKRA-----EPADDMLS-VVANATIDD 232 Query: 277 NQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRS 336 + L LF AG ETT ++ GLL L ++P+ ++ + + Sbjct: 233 PDAPALSDAELYLFFHLLFSAGAETTRNSIAGGLLALAENPDQLQTLRSDFE-------- 284 Query: 337 PCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLH 396 + EI R++ P+ + I G ++ S Sbjct: 285 ----------LLPTAIEEIVRWTSPSPSK-RRTASRAVSLGGQPIEAGQKVVVWEGSANR 333 Query: 397 DDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF 456 D F + FD K + + F G C G LAR+EL + +L F Sbjct: 334 DPSVFDRADEFDITR---------KPNPHLGFGQGVHYCLGANLARLELRVLFEELLSRF 384 Query: 457 NLKSVDDLKNLNTTAVTKGIVSL 479 V + + GI L Sbjct: 385 GSVRVVEPAEWTRSNRHTGIRHL 407 >1CPT-A nrPDB Length = 428 Score = 186 bits (471), Expect = 2e-47, Method: Composition-based stats. Identities = 75/441 (17%), Positives = 144/441 (32%), Gaps = 80/441 (18%) Query: 57 FSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSN 116 + + V + G P + + + E L D E R S + + S + Sbjct: 53 IATKHADVMQI--GKQPGLFSNAEGS--EILYDQNNEAFMRSISGGCPHVID--SLTSMD 106 Query: 117 GKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCN 176 R +L + + R +E+ ++ A V+ L T P + Sbjct: 107 PPTHTAYRGLTLNWFQPASI--RKLEENIRRIAQASVQRLLDFDGECDFMTDCALYYPLH 164 Query: 177 VICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKN 236 V+ + + +D L L L F G H + Sbjct: 165 VVMTALGVP----EDDEPLML-----------------------KLTQDFFGVHEPDEQA 197 Query: 237 VALTRSYIREKVKEHQASL-------------DVNNPRDFIDCFLIKMEQEKDNQKSEFN 283 VA R E + ++ + P+D + L + + + + Sbjct: 198 VAAPRQSADEAARRFHETIATFYDYFNGFTVDRRSCPKDDVMSLLANSKLDGNY----ID 253 Query: 284 IENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRS 343 + + + AG +TTS++ ++ L ++PE A + + + Sbjct: 254 DKYINAYYVAIATAGHDTTSSSSGGAIIGLSRNPEQLALAKSDPALI------------- 300 Query: 344 HMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPN 403 +V E R++ V + + DT+ R I +G IM S D++ F N Sbjct: 301 -----PRLVDEAVRWTAPVKSFM-RTALADTEVRGQNIKRGDRIMLSYPSANRDEEVFSN 354 Query: 404 PNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDD 463 P+ FD F + + F G +C G+ LA++E+ +F +L + Sbjct: 355 PDEFDITRF---------PNRHLGFGWGAHMCLGQHLAKLEMKIFFEELLPKLKSVELSG 405 Query: 464 LKNLNTTAVTKGIVSLPPSYQ 484 L T G ++P + Sbjct: 406 PPRLVATNFVGGPKNVPIRFT 426 >6CVC-A nrPDB Length = 433 Score = 185 bits (469), Expect = 5e-47, Method: Composition-based stats. Identities = 74/414 (17%), Positives = 133/414 (32%), Gaps = 65/414 (15%) Query: 77 FHGYEAVKEALIDNGEEFSGRGNSPI---SQRITKGLG-IISSNGKRWKEIRRFSLTTLR 132 ++ + A + E F N I + + + G +I + R + +R Sbjct: 76 LTKHDDIHFA-SRHPEIFHSSPNIVIHDQTPELAEYFGSMIVLDDPRHQRLRSIVSRAFT 134 Query: 133 NFGMGKRSIEDRVQEEAHCLVEEL-RKTKASPCDPTFILGCA-PCNVICSVVFQKRFDYK 190 + + IE V+E AH LV + D L P +IC ++ + Sbjct: 135 PKVVAR--IEASVRERAHRLVAAMIENHPDGQADLVSELAGPLPLQIICDMMG---IPEE 189 Query: 191 DQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKE 250 D + W V F ++ L+ Y + Sbjct: 190 DHEQI--------------FHWTNVILGFG--DPDLTTDFDEFLQVSMAIGGYATALADD 233 Query: 251 HQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGL 310 + VN+ D +E E D + + + L VAG ETT + +G+ Sbjct: 234 RR----VNHHGDLTTSL---VEAEVDGE--RLSSSEIAMFFILLVVAGNETTRNAISHGM 284 Query: 311 LLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAV 370 L L ++P+ AK + D + V EI R++ V + + Sbjct: 285 LALSRYPDERAKWWSDFDGLAAT-----------------AVEEIVRWASPV-VYMRRTL 326 Query: 371 TTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPF-S 429 + D R + G + S D+++F +P FD + + F Sbjct: 327 SQDVDLRGTKMAAGDKVTLWYCSANRDEEKFADPWTFDVTR---------NPNPQVGFGG 377 Query: 430 AGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSY 483 G C G LAR E+ + + + + + GI LP ++ Sbjct: 378 GGAHFCLGANLARREIRVVFDELRRQMPDVVATEEPARLLSQFIHGIKRLPVAW 431 >5XJN-A nrPDB Length = 455 Score = 184 bits (468), Expect = 5e-47, Method: Composition-based stats. Identities = 79/457 (17%), Positives = 149/457 (32%), Gaps = 76/457 (16%) Query: 45 IDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFS-------GR 97 D+ + ++ + +F G V Y+ +K D+ E FS R Sbjct: 59 FDMHNPFPAYKELRQEEPVMFDERIGYW---VVTKYDDIKTTF-DDWETFSSENAQAPVR 114 Query: 98 GNSPISQRITKGLGIISSNG------KRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHC 151 P + +I G + +G IR + +++E ++ Sbjct: 115 KRGPQATQIMTDGGFTAYSGLSARIPPEHTRIRAIAQKAFTPRRY--KALEPDIRAMVID 172 Query: 152 LVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSP 211 VE++ D L + + D + + KR++++ + Sbjct: 173 RVEKMLANDQHVGDMVSDLAYDIPTITILTLIG-----ADISMVDTYKRWSDSRAAMT-- 225 Query: 212 WIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKM 271 W + + + P H N+ + V + A + D + L++ Sbjct: 226 WGDLSDE-----EQIPHAH-----NLVEYWQECQRMVADAHA-----HGGDNLTADLVRA 270 Query: 272 EQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVI 331 +QE E + + L AG ETT+T + +LL HPE + E + Sbjct: 271 QQEGQ----EITDHEIASLLYSLLFAGHETTTTLISNCFRVLLDHPEQWQAILENPKLI- 325 Query: 332 GRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALL 391 A V E+ RYS + G DT+ I +G ++ L+ Sbjct: 326 -----------------PAAVDEVLRYSGSI-VGWRRKALKDTEIGGVAIKEGDGVLLLM 367 Query: 392 TSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFL-- 449 S D+ F N FD + + F G C G LA+++ + L Sbjct: 368 GSANRDEARFENGEEFDISRANARE--------HLSFGFGIHYCLGNMLAKLQAKICLEE 419 Query: 450 -TTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQI 485 T ++ + +L D + S+P ++ Sbjct: 420 VTRLVPSLHL-VADKAIGFRENLSFRVPTSVPVTWNA 455 >5GWE-A nrPDB Length = 405 Score = 184 bits (468), Expect = 6e-47, Method: Composition-based stats. Identities = 79/457 (17%), Positives = 149/457 (32%), Gaps = 76/457 (16%) Query: 45 IDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFS-------GR 97 D+ + ++ + +F G V Y+ +K D+ E FS R Sbjct: 9 FDMHNPFPAYKELRQEEPVMFDERIGYW---VVTKYDDIKTTF-DDWETFSSENAQAPVR 64 Query: 98 GNSPISQRITKGLGIISSNG------KRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHC 151 P + +I G + +G IR + +++E ++ Sbjct: 65 KRGPQATQIMTDGGFTAYSGLSARIPPEHTRIRAIAQKAFTPRRY--KALEPDIRAMVID 122 Query: 152 LVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSP 211 VE++ D L + + D + + KR++++ + Sbjct: 123 RVEKMLANDQHVGDMVSDLAYDIPTITILTLIG-----ADISMVDTYKRWSDSRAAMT-- 175 Query: 212 WIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKM 271 W + + + P H N+ + V + A + D + L++ Sbjct: 176 WGDLSDE-----EQIPHAH-----NLVEYWQECQRMVADAHA-----HGGDNLTADLVRA 220 Query: 272 EQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVI 331 +QE E + + L AG ETT+T + +LL HPE + E + Sbjct: 221 QQEGQ----EITDHEIASLLYSLLFAGHETTTTLISNCFRVLLDHPEQWQAILENPKLI- 275 Query: 332 GRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALL 391 A V E+ RYS + G DT+ I +G ++ L+ Sbjct: 276 -----------------PAAVDEVLRYSGSI-VGWRRKALKDTEIGGVAIKEGDGVLLLM 317 Query: 392 TSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFL-- 449 S D+ F N FD + + F G C G LA+++ + L Sbjct: 318 GSANRDEARFENGEEFDISRANARE--------HLSFGFGIHYCLGNMLAKLQAKICLEE 369 Query: 450 -TTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQI 485 T ++ + +L D + S+P ++ Sbjct: 370 VTRLVPSLHL-VADKAIGFRENLSFRVPTSVPVTWNA 405 >4XE3-A nrPDB Length = 407 Score = 184 bits (468), Expect = 6e-47, Method: Composition-based stats. Identities = 76/466 (16%), Positives = 145/466 (31%), Gaps = 83/466 (17%) Query: 29 LPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYF--GMNPIVVFHGYEAVKEA 86 +P P LP + L + D + + PV V G + + Sbjct: 14 VPAYPFSLP---HALDL---DPHYAELRRDE---PVSRVRLPYGEGTAWLVTRMSDARIV 64 Query: 87 LIDNGEEFSGRGNSPISQRIT----KGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIE 142 L D+ + P + R+ + G+++ + +RR + Sbjct: 65 LGDSRFSTAA-ATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVGKAFT--ARRVEEMR 121 Query: 143 DRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNVICSVVFQKRFDYKDQNFLTLMKRF 201 RV+ L++++ SP D L P VIC ++ D F T Sbjct: 122 PRVRSLVDSLLDDMVAH-GSPADLVEFLAVPFPVAVICELLGVPLEDRD--LFRTFSDAM 178 Query: 202 NENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPR 261 + R+ + +V +F + Y+ V + + + P Sbjct: 179 LSSTRLTAAEIQRVQQDFMV---------------------YMDGLVAQRR-----DAPT 212 Query: 262 DFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTA 321 + + L + +V L +AG ET+ + + LLL + Sbjct: 213 EDLLGALALAT----DNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHLLLTERKRYE 268 Query: 322 KVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVP-HAVTTDTKFRNYL 380 + + V A V E+ RY+ LV G T D + Sbjct: 269 SLVADPALV------------------PAAVEEMLRYTPLVSAGSFVRVATEDVELSTVT 310 Query: 381 IPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGL 440 + G + S D++ F + + D ++ + + F G C G L Sbjct: 311 VRAGEPCVVHFASANRDEEVFDHADELD---------FHRERNPHIAFGHGAHHCIGAQL 361 Query: 441 ARMELFLFLTTILQNF---NLKSVDDLKNLNTTAVTKGIVSLPPSY 483 R+EL L+ +++ F +L + +G+ S+ Sbjct: 362 GRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW 407 >4JBT-A nrPDB Length = 410 Score = 183 bits (465), Expect = 1e-46, Method: Composition-based stats. Identities = 71/411 (17%), Positives = 136/411 (33%), Gaps = 76/411 (18%) Query: 62 GPVFTVYFGMNPIVVFHGYEAVKEALIDN-----------GEEFSGRGNSPISQRITKGL 110 GP+ + P + G+ ++ L D + + P+ I Sbjct: 30 GPLTRIDLLGVPALAVTGHTLARQLLTDTRLVKDINAWSLWQSGTVTRQWPLIGMIDVDR 89 Query: 111 GIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTK--ASPCDPTF 168 + + +G + +R TT +++ ++ L+++L + + D Sbjct: 90 SMFTVDGPEHRRLR--IKTTQALTRRRLDALKPTIERYVAELLDDLERAGADGAVVDLKS 147 Query: 169 ILGCA-PCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFP 227 + P VI +++ D + L+ + F IL Sbjct: 148 VFAYPLPMRVISALMGVPSEDQE-----QLLTWYKAFFSILT------------------ 184 Query: 228 GTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENL 287 ++ L+ + Y E V+ A P D + LI + ++ E + Sbjct: 185 -PQDERLRVIDEMHGYFTEMVRRKTA-----EPGDDLTSALIYAT----DGETPLTEEEV 234 Query: 288 VGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPY 347 +G + L AG ETT + + + LL HPE V+ D IG Sbjct: 235 IGNLQALVAAGHETTVSLILTAVRALLSHPEQLRLVR---DGEIG--------------- 276 Query: 348 TDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEF-PNPNI 406 + + E R+ V + T D + +IP+G ++ ++ D + + Sbjct: 277 WETAIEETLRWDGPVIHLLMRFATEDIDLGDAVIPRGEGVVMSYRAIGRDITVHGADADD 336 Query: 407 FDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFN 457 FD + + F G IC G LAR+E + L + F Sbjct: 337 FDITRA--------TAARHISFGHGPHICPGAALARLEAAIALPALFTRFP 379 >5XNT-A nrPDB Length = 411 Score = 182 bits (463), Expect = 2e-46, Method: Composition-based stats. Identities = 86/415 (20%), Positives = 148/415 (35%), Gaps = 73/415 (17%) Query: 80 YEAVKEALIDNGEEFSGRGNSPIS-------QRITKGLGIISSNGKRWKEIRRFSLTTLR 132 YE VK L D S R + IS + + I ++ ++ R Sbjct: 49 YEDVKRVLSDYKHFSSVRKRTTISVGTDSEEGSVPDKIKITEADPPEHRKRRSLLAAAFT 108 Query: 133 NFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNVICSVVFQKRFDYKD 191 + ++ E R+QE A L+EE+ + + D L P V+ ++ D Sbjct: 109 PRSL--QNWEPRIQEIADELIEEMDEE--TEIDIVQSLASPLPIIVMSDLMGVPSKD--- 161 Query: 192 QNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLK-NVALTRSYIREKVKE 250 R+L W+ + F N++ + Y+ V + Sbjct: 162 --------------RLLFKKWVDIL--FLPFDKEKQEEVNELKQVAAKEYYQYLYPIVVQ 205 Query: 251 HQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGL 310 + NP D I L+K E + + F + +V T + AG ETTS L Sbjct: 206 KRL-----NPADDIISDLLKAEVDGEM----FTDDEVVRTTMLILGAGVETTSHLLANSF 256 Query: 311 LLLL-KHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHA 369 LL EV ++ E +D V V E+ RY + Sbjct: 257 YSLLYDDKEVYQELHENLDLV------------------PQAVEEMLRYR-FNLIKLDRT 297 Query: 370 VTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFS 429 V D + +G ++ +++ D++ F + + +K + F Sbjct: 298 VKEDNDLLGVELKEGENVVVWMSAANLDEEMFEDAFTLNIHRPNNKK--------HLTFG 349 Query: 430 AGKRICAGEGLARMELFLFLTTILQNF-NLKSVDDLK---NLNTTAVTKGIVSLP 480 G C G LAR+E + LTT L+ F ++++V + NL +A + + SLP Sbjct: 350 NGPHFCLGAPLARLEAKIALTTFLKKFKHIEAVPSFQLEDNLTDSATGQTLTSLP 404 >5L1U-A nrPDB Length = 401 Score = 182 bits (462), Expect = 3e-46, Method: Composition-based stats. Identities = 87/439 (19%), Positives = 149/439 (33%), Gaps = 79/439 (17%) Query: 59 KVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISS--- 115 + GP+ V + Y+ V+ L D S P ++ + + + Sbjct: 28 QKEGPIARVGTAGEDAWLVTRYDEVRTLLADRRLRLSNPNPQPSAKSAARAFMVALAAGD 87 Query: 116 ----NGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILG 171 R ++R + R R ++ R++ L+++L + A P D +L Sbjct: 88 DHETEPARHAQMRSLLIP--RFSTRRLRLMKTRIEHHVDELLDQLAAS-APPVDLHRVLS 144 Query: 172 -CAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTH 230 P V+C ++ D + + + Q N + T Sbjct: 145 FRLPTMVVCDLLGVPLADRE------------RFGQWARGTFDQSDN------EHSANTF 186 Query: 231 NKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGT 290 +V+ Y+ E V + P D I LI EKD S+ +I +L G Sbjct: 187 QQVV-------DYMLELVARKRV-----EPGDDILSELIA---EKDGALSDADIAHL-GN 230 Query: 291 VADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDA 350 LF G ETT + G LLLL++P A++ E+ A Sbjct: 231 AVLLF--GYETTIVRIDLGTLLLLRNPVQRAQLAEDPG------------------LAPA 270 Query: 351 VVHEIQRYS---DLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIF 407 V EI R +P D +I G +M + + +DD+ FP+ +F Sbjct: 271 AVEEILRLGVGGKGSNALIPRYAHGDITVGETVIRTGDAVMLAIGAANYDDRAFPDGGLF 330 Query: 408 DPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQN---FNLKSVDDL 464 D + + F G R C G LAR+EL + + L ++ Sbjct: 331 DLTRV--------RPRSHLAFGHGARHCIGRTLARIELTAVFERLFRRLPDLRLAVPEES 382 Query: 465 KNLNTTAVTKGIVSLPPSY 483 +T G +P ++ Sbjct: 383 LRWQEHRITGGFDEIPVTF 401 >4GGV-A nrPDB Length = 418 Score = 182 bits (461), Expect = 4e-46, Method: Composition-based stats. Identities = 72/422 (17%), Positives = 137/422 (32%), Gaps = 69/422 (16%) Query: 64 VFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEI 123 V+ VY + + + ++ + + + + +G + + R ++ Sbjct: 55 VWNVYGYPEAMDILNDHDTF-------TSDLAHLLPVSVDAPLLEG-DMSQMDPPRHRKY 106 Query: 124 RRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEEL--RKTKASPCDPTFILGCAPCNVICSV 181 R+ + +E RV + L++ + + D + L VI + Sbjct: 107 RQLVSRAFTPRLVAD--METRVADITRELLDAVDGKPEIEIAADLAYPLPVI---VIAEL 161 Query: 182 VFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTH--NKVLKNVAL 239 + D F+ I+ + F L G + + Sbjct: 162 LGVPAGDRD-------------LFKKWADDIIEGFSGFSFLDTSGQGEQDVRDATERLRP 208 Query: 240 TRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGT 299 Y+ V E + + PR+ + L++ E + + +V L V G Sbjct: 209 LLDYMAGHVTERRRT-----PREDLLTHLVQAEVDGE----RLTDNEIVNVANILLVTGH 259 Query: 300 ETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYS 359 TT+ TL +L L PEV AKV+ + V G + E R Sbjct: 260 ITTTMTLGNTVLCLDADPEVAAKVRADRSLVPG------------------AIEEALRVL 301 Query: 360 DLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNF 419 + + + + +IPK +M L + D ++F +P ++DP Sbjct: 302 SPS-AALARGTSREVEVAGTVIPKDQIVMLWLGAGNRDPRQFTDPEVYDPTR-------- 352 Query: 420 KKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLN--TTAVTKGIV 477 + F G C G LAR+E + L + F + D K T G+ Sbjct: 353 -DPNPHFGFGRGIHFCLGAPLARLEGRVALNALFDRFPVLRTDPAKPPTFFPTPDMIGVN 411 Query: 478 SL 479 +L Sbjct: 412 TL 413 >4YT3-A nrPDB Length = 410 Score = 181 bits (460), Expect = 4e-46, Method: Composition-based stats. Identities = 83/414 (20%), Positives = 144/414 (34%), Gaps = 71/414 (17%) Query: 80 YEAVKEALIDNGEEFSGRGNSPIS-------QRITKGLGIISSNGKRWKEIRRFSLTTLR 132 YE VK L D S R + IS + + + I S+ ++ R Sbjct: 49 YEDVKRVLSDYKHFSSVRKRTTISVGTDSEEGSVPEKIQITESDPPDHRKRRSLLAAAFT 108 Query: 133 NFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNVICSVVFQKRFDYKD 191 + ++ E R+QE A L+ ++ + D L P V+ ++ D Sbjct: 109 PRSL--QNWEPRIQEIADELIGQM--DGGTEIDIVASLASPLPIIVMADLMGVPSKD--- 161 Query: 192 QNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEH 251 R+L W+ P + Y+ V + Sbjct: 162 --------------RLLFKKWVDTL-FLPFDREKQEEVDKLKQVAAKEYYQYLYPIVVQK 206 Query: 252 QASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLL 311 + NP D I L+K E + + F + +V T + AG ETTS L Sbjct: 207 RL-----NPADDIISDLLKSEVDGEM----FTDDEVVRTTMLILGAGVETTSHLLANSFY 257 Query: 312 LLL-KHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAV 370 LL EV ++ E +D V V E+ R+ + V Sbjct: 258 SLLYDDKEVYQELHENLDLV------------------PQAVEEMLRFR-FNLIKLDRTV 298 Query: 371 TTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSA 430 D + +G +++ +++ D++ F +P + +K + F Sbjct: 299 KEDNDLLGVELKEGDSVVVWMSAANMDEEMFEDPFTLNIHRPNNKK--------HLTFGN 350 Query: 431 GKRICAGEGLARMELFLFLTTILQNF-NLKSVDD---LKNLNTTAVTKGIVSLP 480 G C G LAR+E + LT L+ F ++++V +NL +A + + SLP Sbjct: 351 GPHFCLGAPLARLEAKIALTAFLKKFKHIEAVPSFQLEENLTDSATGQTLTSLP 404 >1ODO-A nrPDB Length = 408 Score = 181 bits (460), Expect = 4e-46, Method: Composition-based stats. Identities = 72/423 (17%), Positives = 125/423 (29%), Gaps = 80/423 (18%) Query: 77 FHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGII---------SSNGKRWKEIRRFS 127 +K+ L + R + P + + ++ G +++RR Sbjct: 43 VSDPVLLKQLLTSSDVSKDARAHWPAFGEVVGTWPLALWVAVENMFTAYGPNHRKLRRLV 102 Query: 128 LTTLRNFGMGKRSIEDRVQEEAHCLVEELRKT-KASPCDPTFILGCA-PCNVICSVVFQK 185 ++ V+ LV+ L + P D L P VI Sbjct: 103 APAFS--ARRVDAMRPAVEAMVTGLVDRLAELPAGEPVDLRQELAYPLPIAVI------- 153 Query: 186 RFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHN---KVLKNVALTRS 242 ++ P + F L+D T + N A Sbjct: 154 -------------------GHLMGVP-QDRRDGFRALVDGVFDTTLDQAEAQANTARLYE 193 Query: 243 YIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETT 302 + + + +A+ P D + LI + + + E L T+ + AG ETT Sbjct: 194 VLDQLIAAKRAT-----PGDDMTSLLIAAR-DDEGDGDRLSPEELRDTLLLMISAGYETT 247 Query: 303 STTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLV 362 + + LL P+ A V++ D VV E R+ V Sbjct: 248 VNVIDQAVHTLLTRPDQLALVRK---------GEVTWAD---------VVEETLRHEPAV 289 Query: 363 PTGVPHAVTTDTKF-RNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKK 421 TD I +G I+A + + + FD + + Sbjct: 290 KHLPLRYAVTDIALPDGRTIARGEPILASYAAANRHPDWHEDADTFDATRTVKE------ 343 Query: 422 SDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF---NLKSVDDLKNLNTTAVTKGIVS 478 + F G C G LARME+ L L ++ F L + + ++ G Sbjct: 344 ---HLAFGHGVHFCLGAPLARMEVTLALESLFGRFPDLRLADPAEELPPVPSLISNGHQR 400 Query: 479 LPP 481 LP Sbjct: 401 LPV 403 >3MGX-A nrPDB Length = 415 Score = 181 bits (458), Expect = 8e-46, Method: Composition-based stats. Identities = 71/413 (17%), Positives = 137/413 (33%), Gaps = 71/413 (17%) Query: 77 FHGYEAVKEALIDNGEEFSGRGNSPISQR----ITKGLGIISSNGKRWKEIRRFSLTTLR 132 + A L + S G R + G ++ S ++ +++R+ L Sbjct: 67 VFSHRACAAVLAPSAPLTSEYGMMIGFDRDHPDNSGGRMMVVSEHEQHRKLRKLVGPLLS 126 Query: 133 NFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILG-CAPCNVICSVVFQKRFDYKD 191 R + +RV+ E ++ + CD +G P V+C ++ +D Sbjct: 127 R--AAARKLAERVRIEVGDVLGRV--LDGEVCDAATAIGPRIPAAVVCEILG---VPAED 179 Query: 192 QNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEH 251 ++ L + N + F + + Y E + Sbjct: 180 EDML---------IDLTNHAFGGEDELFDGMTPR---------QAHTEILVYFDELITAR 221 Query: 252 QASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLL 311 + P D + L+ + I++++ ++ + G ETT + + Sbjct: 222 RK-----EPGDDLVSTLV--------TDDDLTIDDVLLNCDNVLIGGNETTRHAITGAVH 268 Query: 312 LLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVT 371 L P + +++ V D VV E+ R++ V T Sbjct: 269 ALATVPGLLTALRDGSADV------------------DTVVEEVLRWTSPA-MHVLRVTT 309 Query: 372 TDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAG 431 D +P GT ++A L + D EF +P+ F PG K + + F G Sbjct: 310 ADVTINGRDLPSGTPVVAWLPAANRDPAEFDDPDTFLPGR---------KPNRHITFGHG 360 Query: 432 KRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQ 484 C G LAR+EL + L + + + ++ V +G LP + Sbjct: 361 MHHCLGSALARIELSVVLRVLAERVSRVDLEREPAWLRAIVVQGYRELPVRFT 413 >1GWI-A nrPDB Length = 411 Score = 181 bits (458), Expect = 8e-46, Method: Composition-based stats. Identities = 74/429 (17%), Positives = 134/429 (31%), Gaps = 74/429 (17%) Query: 63 PVFTVYFGMNPIVVFHGYEAVKEALI----DNGEEFSGRGNSPISQRITKGLGIISSNGK 118 PV+ V + VK+ + GE + + P+ G +++ +G Sbjct: 42 PVWAVTHHAEAKALLTDPRLVKDINVWGAWRRGEIPA---DWPLIGLANPGRSMLTVDGA 98 Query: 119 RWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNV 177 + +R L + + R+ E L++EL D P V Sbjct: 99 EHRRLRTLVAQALTVRRV--EHMRGRITELTDRLLDELPADGGV-VDLKAAFAYPLPMYV 155 Query: 178 ICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNV 237 + ++ ++ L F + F P +V+ + Sbjct: 156 VADLMGI-----EEARLPRLKVLFEKFFSTQTPP-------------------EEVVATL 191 Query: 238 ALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVA 297 S + + V +A+ P D + LI+ + D +V T+ + A Sbjct: 192 TELASIMTDTVAAKRAA-----PGDDLTSALIQASENGD----HLTDAEIVSTLQLMVAA 242 Query: 298 GTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQR 357 G ETT + + ++ L HPE A V S AVV E R Sbjct: 243 GHETTISLIVNAVVNLSTHPEQRALV------------------LSGEAEWSAVVEETLR 284 Query: 358 YSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEF-PNPNIFDPGHFLDKN 416 +S + D + +IP G ++ ++ D++ P + FD Sbjct: 285 FSTPTSHVLIRFAAEDVPVGDRVIPAGDALIVSYGALGRDERAHGPTADRFDLTRT---- 340 Query: 417 GNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF---NLKSVDDLKNLNTTAVT 473 + + F G +C G L+RME + L + F +L Sbjct: 341 ----SGNRHISFGHGPHVCPGAALSRMEAGVALPALYARFPHLDLAVPAAELRNKPVVTQ 396 Query: 474 KGIVSLPPS 482 + LP Sbjct: 397 NDLFELPVR 405 >4Z5Q-A nrPDB Length = 423 Score = 180 bits (456), Expect = 1e-45, Method: Composition-based stats. Identities = 70/457 (15%), Positives = 143/457 (31%), Gaps = 70/457 (15%) Query: 31 PGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYF-GMNPIVVFHGYEAVKEALID 89 P P P G+ + ++ +S+ + G V P + Y+ + L D Sbjct: 33 PAPVAYPFTGS----EGLELSQSYAKLFED-GDPIRVQLPFGEPAWLVTRYDDARFVLTD 87 Query: 90 N--GEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQE 147 + + + P I++ + +R + + + E Sbjct: 88 RRFSRHLATQRDEPRMTPRAVPESILTMDPPDHTRLRTLVSKAFTPRRIESK--RAWIGE 145 Query: 148 EAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRI 207 A LV +++ A P VIC ++ D+ L Sbjct: 146 LAAGLVADMKAGGAPAELVGSYALAIPVTVICELLG---VPEDDRTRLR----------- 191 Query: 208 LNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCF 267 W + L D + +++ + Y + VKE +A PRD + Sbjct: 192 ---GWCDAALSTGELTD------EECVQSFMDLQKYFEDLVKERRA-----EPRDDLTSA 237 Query: 268 LIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEI 327 LI+ + L+G + + G ETT++ + + +L + E+ ++ + Sbjct: 238 LIEAR----DAHDRLAEPELIGLCISILIGGFETTASEISSFVHVLQQRRELWTRLCADP 293 Query: 328 DHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGV-PHAVTTDTKFRNYLIPKGTT 386 + + A V E+ R+ G+ P D L+ +G Sbjct: 294 EAI------------------PAAVEELLRFVPFAANGISPRYALEDMTVGGVLVREGEP 335 Query: 387 IMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELF 446 ++ ++V D F N + ++ M F G C G LAR+EL Sbjct: 336 VIVDTSAVNRDGLVFDNADEVVIDRADNR---------HMVFGHGAHHCLGAHLARVELQ 386 Query: 447 LFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSY 483 L +++ + + + + + Sbjct: 387 EALKALVEGMPGLRLSGDVEWKADMIIRAPRVMHVEW 423 >4TRI-A nrPDB Length = 407 Score = 177 bits (450), Expect = 7e-45, Method: Composition-based stats. Identities = 87/436 (19%), Positives = 150/436 (34%), Gaps = 84/436 (19%) Query: 63 PVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSG----RGNSPISQRITKGLGIISSNGK 118 PVF G + Y+AV +A N E FS R + P +I + Sbjct: 35 PVFRDRNG---LAAATTYQAVLDA-ERNPELFSSTGGIRPDQP------GMPYMIDMDDP 84 Query: 119 RWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEEL--RKTKASPCDPTFILGCA-PC 175 + R+ N G ++ + D+V L + L + CD + P Sbjct: 85 QHLLRRKLV-----NAGFTRKRVMDKVDSIGR-LCDTLIDAVCERGECDFVRDIAAPLPM 138 Query: 176 NVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLK 235 VI ++ + L+K ++ L+S + K++ Sbjct: 139 AVIGDMLGVLPTERD-----MLLKWSDDLVCGLSSHVDE-------------AAIQKLMD 180 Query: 236 NVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLF 295 A + ++ + + +A P D + L+ E E + + +V + Sbjct: 181 TFAAYTEFTKDVITKRRA-----EPTDDLFSVLVNSEVEGQ----RMSDDEIVFETLLIL 231 Query: 296 VAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEI 355 + G ETT TL G LL+H + + ++D + G + E+ Sbjct: 232 IGGDETTRHTLSGGTEQLLRHRDQWDALVADVDLLPG------------------AIEEM 273 Query: 356 QRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDK 415 R++ V + +T DT F + G IM + S D+ F +P+ F Sbjct: 274 LRWTSPV-KNMCRTLTADTVFHGTELRAGEKIMLMFESANFDESVFGDPDNFRIDR---- 328 Query: 416 NGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF-NLKSVDDLK-NLNTTAVT 473 + + F G C G LAR+EL L +L+ +L+ DD L Sbjct: 329 -----NPNSHVAFGFGTHFCLGNQLARLELRLMTERVLRRLPDLRLADDAPVPLRPANFV 383 Query: 474 KGIVSLPPSYQICFIP 489 G P S + F P Sbjct: 384 SG----PESMPVVFTP 395 >5Z9I-A nrPDB Length = 398 Score = 176 bits (447), Expect = 2e-44, Method: Composition-based stats. Identities = 66/373 (17%), Positives = 123/373 (32%), Gaps = 53/373 (14%) Query: 111 GIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFIL 170 ++ + + +R + K +E RV H L++ + D Sbjct: 74 DFAHTDPPKHRRLRGLVDHAFTPSLVAK--MESRVHGIIHELLDGVEGKSQ--FDLVAEF 129 Query: 171 GCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTH 230 ++ S + + F M + + SP + Sbjct: 130 AAPLPLIMISDLLGVP-ESDRALFRQWMDKMLDGSEKFESPET---------VLEQEEEL 179 Query: 231 NKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGT 290 +K L+ + R Y E+ E + PR+ + L+ E + + N + Sbjct: 180 HKELELLWEMRDYWHERAAESRK-----RPREDLISQLVHAEVDGQ----KLNDSQISNI 230 Query: 291 VADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDA 350 L V G TT+ + +L L + A+V+ DRS +P A Sbjct: 231 ANRLLVNGHLTTAMLIANTMLCLDAFSDQDARVRA---------------DRSLVP---A 272 Query: 351 VVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPG 410 ++ E RY + GV A ++ + +IPK ++ + D+++F P++FD G Sbjct: 273 LLEESMRYMSPI-CGVGRATNSEVEVAGTVIPKDQLLLVWTGAANRDERQFEKPDVFDAG 331 Query: 411 HFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFN--LKSVDDLKNLN 468 + + F G C G LARME + +L + Sbjct: 332 R---------SPNAHLGFGRGIHFCLGRQLARMESKAAVEILLDRLPTLRADPANPPTFL 382 Query: 469 TTAVTKGIVSLPP 481 G+ +LP Sbjct: 383 QVVDASGVATLPV 395 >2XKR-A nrPDB Length = 398 Score = 176 bits (446), Expect = 2e-44, Method: Composition-based stats. Identities = 82/429 (19%), Positives = 141/429 (32%), Gaps = 75/429 (17%) Query: 63 PVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSG----RGNSPISQRITKGLGIISSNGK 118 PVF G + Y+AV +A E FS R + P + Sbjct: 32 PVFRDRNG---LAAASTYQAVIDA-ERQPELFSNAGGIRPDQPALPMMIDMDDPA----- 82 Query: 119 RWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVI 178 +RR + K E + L++ + + + P VI Sbjct: 83 --HLLRRKLVNAGFTRKRVKDK-EASIAALCDTLIDAVCERGECDF-VRDLAAPLPMAVI 138 Query: 179 CSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVA 238 ++ + + FL L+S Q +F + +D F A Sbjct: 139 GDMLGVR--PEQRDMFLRWSDDL---VTFLSSHVSQ--EDFQITMDAF-----------A 180 Query: 239 LTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAG 298 + R + +A +P D + L+ E + + + + LV + + G Sbjct: 181 AYNDFTRATIAARRA-----DPTDDLVSVLVSSEVDGE----RLSDDELVMETLLILIGG 231 Query: 299 TETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRY 358 ETT TL G LL++ + +Q + + G + E+ R+ Sbjct: 232 DETTRHTLSGGTEQLLRNRDQWDLLQRDPSLLPG------------------AIEEMLRW 273 Query: 359 SDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGN 418 + V + +T DT+F + G +M L S D+ F P FD Sbjct: 274 TAPV-KNMCRVLTADTEFHGTALCAGEKMMLLFESANFDEAVFCEPEKFDVQR------- 325 Query: 419 FKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQN---FNLKSVDDLKNLNTTAVTKG 475 + + F G C G LAR+EL L +L+ L + D + L G Sbjct: 326 --NPNSHLAFGFGTHFCLGNQLARLELSLMTERVLRRLPDLRLVADDSVLPLRPANFVSG 383 Query: 476 IVSLPPSYQ 484 + S+P + Sbjct: 384 LESMPVVFT 392 >3P3Z-A nrPDB Length = 416 Score = 174 bits (441), Expect = 7e-44, Method: Composition-based stats. Identities = 61/374 (16%), Positives = 118/374 (31%), Gaps = 60/374 (16%) Query: 114 SSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCA 173 S +G + +R + T +++ V+ L+++L D Sbjct: 102 SLDGADHRRLRGLA--THPFTPRRITAVQPFVRSTVEQLIDKL---PQGDFDFVQHFPHP 156 Query: 174 -PCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNK 232 P V+C ++ DY L++ + + N+ +L+ G Sbjct: 157 LPALVMCQLLGFPLEDYDTVGRLSIETNL----------GLALSNDQDILVKVEQGLGR- 205 Query: 233 VLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVA 292 Y+ +++ + P D + +++ + + L VA Sbjct: 206 -------MFDYLVAAIEKRKV-----EPGDDLTSDIVRAFHDG-----VLDDYELRTLVA 248 Query: 293 DLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVV 352 + VAG ETT+ L + +HP+ K++E + V Sbjct: 249 TVLVAGYETTNHQLALAMYDFAQHPDQWMKIKENPE------------------LAPQAV 290 Query: 353 HEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHF 412 E+ R+S +P D + IP GT + D + F + + FD Sbjct: 291 EEVLRWSPTLPVTATRVAAEDFEVNGVRIPTGTPVFMCAHVAHRDPRVFADADRFDIT-- 348 Query: 413 LDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAV 472 K+ + F G C G LAR+EL + + + + Sbjct: 349 ------VKREAPSIAFGGGPHFCLGTALARLELTEAVAALATRLDPPQIAGEITWRHELG 402 Query: 473 TKGIVSLPPSYQIC 486 G +LP + Sbjct: 403 VAGPDALPLRFGAA 416 >3S79-A nrPDB Length = 503 Score = 172 bits (435), Expect = 4e-43, Method: Composition-based stats. Identities = 87/434 (20%), Positives = 156/434 (35%), Gaps = 31/434 (7%) Query: 37 PII--GNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEF 94 P+I G L + + C + VYG V+ ++ ++ + N Sbjct: 58 PLISHGRFLWMGIGSACNYYNR---VYGEFMRVWISGEETLIISKSSSMFHIMKHNHYSS 114 Query: 95 SGRGNSPISQRITKGLGIISSNGKR-WKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLV 153 + GII +N WK R F + L G G + E + Sbjct: 115 RFGSKLGLQCIGMHEKGIIFNNNPELWKTTRPFFMKALS--GPGLVRMVTVCAESLKTHL 172 Query: 154 EELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWI 213 + L + +V+ + + D + FL + + + Sbjct: 173 DRLEEVTNES---------GYVDVLTLLR-RVMLDTSNTLFLR-IPLDESAIVVKIQGYF 221 Query: 214 QVCNNFPLLIDCFPG---THNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIK 270 + D F + K K+V + I + E + + +C Sbjct: 222 DAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEK--LEECMDFA 279 Query: 271 MEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHV 330 E ++ + EN+ + ++ +A +T S +L + L L+ KHP V + +EI V Sbjct: 280 TELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTV 339 Query: 331 IGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMAL 390 IG R + D + + ++E RY +V V D Y + KGT I+ Sbjct: 340 IG-ERDIKIDDIQKLKVMENFIYESMRYQPVVDL-VMRKALEDDVIDGYPVKKGTNIILN 397 Query: 391 LTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLT 450 + + + FP PN F +F YF PF G R CAG+ +A + + L Sbjct: 398 IGRMHRLE-FFPKPNEFTLENF----AKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILV 452 Query: 451 TILQNFNLKSVDDL 464 T+L+ F++K++ Sbjct: 453 TLLRRFHVKTLQGQ 466 >6M7X-A nrPDB Length = 484 Score = 171 bits (433), Expect = 7e-43, Method: Composition-based stats. Identities = 74/440 (16%), Positives = 140/440 (31%), Gaps = 28/440 (6%) Query: 19 LWRQSCR--RRKLP-------PGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYF 69 + +++ R LP PG L ++ + +D+ + GP+F Sbjct: 1 MAKKTSSVPRTVLPFEAMPRRPGNRWLRLLQIWREQGYEDLHLEVHQTFQELGPIFRYDL 60 Query: 70 GMNPIVVFHGYEAVK---EALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRF 126 G +V E V+ + + S Q G+ NG W+ R Sbjct: 61 GGAGMVCVMLPEDVEKLQQVDSLHPHRMSLEPWVAYRQHRGHKCGVFLLNGPEWRFNR-L 119 Query: 127 SLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPC------DPTFILGCAPCNVICS 180 L + V A + L+K D + Sbjct: 120 RLNPEVLSPNAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTLDVQPSIFHYTIEASNL 179 Query: 181 VVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLID-CFPGTHNKVLKNVAL 239 +F +R + + F ++ +Q+ L P + + Sbjct: 180 ALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFMPRSLSRWTSPKVWKEHFEAWDC 239 Query: 240 TRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGT 299 Y +++ L + P+ + + +E + + + +L Sbjct: 240 IFQYGDNCIQKIYQELAFSRPQQYTSIVAELLL------NAELSPDAIKANSMELTAGSV 293 Query: 300 ETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYS 359 +TT L L L ++P V +++E + + +P A + E R Sbjct: 294 DTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLRAALKETLRLY 353 Query: 360 DLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNF 419 V + ++D +NY IP GT + L S+ + FP P ++P +LD G+ Sbjct: 354 P-VGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIRGSG 412 Query: 420 KKSDYFMPFSAGKRICAGEG 439 + Y +PF G R C G Sbjct: 413 RN-FYHVPFGFGMRQCLGRR 431 >4ZGX-A nrPDB Length = 489 Score = 170 bits (431), Expect = 1e-42, Method: Composition-based stats. Identities = 71/412 (17%), Positives = 135/412 (32%), Gaps = 23/412 (5%) Query: 42 MLQIDVKDICKSF-TNFSKVY---GPVFTVYFGMNPIVVFHGYEAVK---EALIDNGEEF 94 +LQI + + + + GP+F G +V E V+ + + Sbjct: 29 LLQIWREQGYEHLHLEMHQTFQELGPIFRYNLGGPRMVCVMLPEDVEKLQQVDSLHPCRM 88 Query: 95 SGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVE 154 Q G+ NG W+ R L + V A + Sbjct: 89 ILEPWVAYRQHRGHKCGVFLLNGPEWRFNR-LRLNPDVLSPKAVQRFLPMVDAVARDFSQ 147 Query: 155 ELRKTKASPC------DPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRIL 208 L+K D + +F +R + + F ++ Sbjct: 148 ALKKKVLQNARGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVM 207 Query: 209 NSPWIQVCNNFPLLID-CFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCF 267 +Q+ L P + + Y +++ L N P+ + Sbjct: 208 FKSTVQLMFMPRSLSRWISPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFNRPQHYTGIV 267 Query: 268 LIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEI 327 + + +E ++E + +L +TT+ L L L ++P+V +++E Sbjct: 268 AELLLK------AELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQES 321 Query: 328 DHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTI 387 + + +P A + E R V + V++D +NY IP GT + Sbjct: 322 LAAAASISEHPQKATTELPLLRAALKETLRLYP-VGLFLERVVSSDLVLQNYHIPAGTLV 380 Query: 388 MALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEG 439 L S+ + FP P ++P +LD G+ + + +PF G R C G Sbjct: 381 QVFLYSLGRNAALFPRPERYNPQRWLDIRGSGRN-FHHVPFGFGMRQCLGRR 431 >3NC3-A nrPDB Length = 441 Score = 169 bits (427), Expect = 3e-42, Method: Composition-based stats. Identities = 81/443 (18%), Positives = 150/443 (33%), Gaps = 58/443 (13%) Query: 46 DVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQR 105 + F+ + PV Y Y V+ L + + F+ + ++ Sbjct: 51 FQNNPYAYFSQLREE-DPVH--YEESIDSYFISRYHDVRYIL-QHPDIFTTKSLVERAEP 106 Query: 106 ITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEE-LRKTKASPC 164 + +G + +GK RR + + G + +++ A L+ L + K+ Sbjct: 107 VMRGPVLAQMHGKEHSAKRRIVVRSF--IGDALDHLSPLIKQNAENLLAPYLERGKSDLV 164 Query: 165 -DPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLI 223 D + L L KR +E S W +F I Sbjct: 165 NDFGKTFAVCVTM----------------DMLGLDKRDHEKI----SEWHSGVADFITSI 204 Query: 224 DCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFN 283 P L Y+ +KE + NP + L E E + Sbjct: 205 SQSPEARAHSLWCSEQLSQYLMPVIKERRV-----NPGSDLISILCTSEYEGMA----LS 255 Query: 284 IENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRS 343 ++++ + ++ +A TE TL + LL +PE V + DRS Sbjct: 256 DKDILALILNVLLAATEPADKTLALMIYHLLNNPEQMNDV---------------LADRS 300 Query: 344 HMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPN 403 +P + E RY V +P ++ DT I K T + ++ + D + F Sbjct: 301 LVP---RAIAETLRYKPPVQL-IPRQLSQDTVVGGMEIKKDTIVFCMIGAANRDPEAFEQ 356 Query: 404 PNIFDPGHF-LDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFN-LKSV 461 P++F+ L F + + F +G C G A+ E+ + +L ++ Sbjct: 357 PDVFNIHREDLGIKSAFSGAARHLAFGSGIHNCVGTAFAKNEIEIVANIVLDKMRNIRLE 416 Query: 462 DDLKNLNTTAVTKGIVSLPPSYQ 484 +D + T+G VSL ++ Sbjct: 417 EDFCYAESGLYTRGPVSLLVAFD 439 >3OO3-A nrPDB Length = 384 Score = 168 bits (425), Expect = 6e-42, Method: Composition-based stats. Identities = 61/413 (14%), Positives = 126/413 (30%), Gaps = 76/413 (18%) Query: 76 VFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFG 135 + G++ V+ L D+ S R + R + + + +RR Sbjct: 43 LVTGHDEVRAILADHERFSSMRPVDDEADRALLPGILQAYDPPDHTRLRRTVAPAYSARR 102 Query: 136 MGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNVICSVVFQKRFDYKDQNF 194 M + R++E +++ ++ +P D P + C + R D + + Sbjct: 103 M--ERLRPRIEEIVEECLDDF-ESVGAPVDFVRHAAWPIPAYIACEFLGVPRDDQAELSR 159 Query: 195 LTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQAS 254 + R + R + + N + S Sbjct: 160 MIRESRESRLPRQRTLSGLGIVNY------------------------------TKRLTS 189 Query: 255 LDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLL 314 +P D + +++ +E + E L G + E + L +LLL+ Sbjct: 190 GKRRDPGDGMIGVIVR------EHGAEISDEELAGLAEGNLIMAAEQMAAQLAVAVLLLV 243 Query: 315 KHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDT 374 HP+ A ++E+ + + D+ E+ R++ +V P D Sbjct: 244 THPDQMALLREKPELI------------------DSATEEVLRHASIVEAPAPRVALADV 285 Query: 375 KFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRI 434 + I G + + + + FD + M F G Sbjct: 286 RMAGRDIHAGDVLTCSMLATNRAP-----GDRFDITR---------EKATHMAFGHGIHH 331 Query: 435 CAGEGLARMELFLFLTTILQNF---NLKSVDDLKNLNTT-AVTKGIVSLPPSY 483 C G LAR++L + L ++ F L ++ + LP + Sbjct: 332 CIGAPLARLQLRVALPAVVGRFPSLRLAVPEEDLRFKPGRPAPFAVEELPLEW 384 >3A1L-A nrPDB Length = 425 Score = 167 bits (422), Expect = 1e-41, Method: Composition-based stats. Identities = 72/382 (18%), Positives = 126/382 (32%), Gaps = 62/382 (16%) Query: 76 VFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLG---IISSNGKRWKEIRRFSLTTLR 132 V + A + +G+ + P R + + ++ + E+R T Sbjct: 59 VLSNRRLGRNARVASGDTDTAPVPIPTEHRALRTVVENWLVFLDPPHHTELRSLLTTEFS 118 Query: 133 NFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCA-PCNVICSVVFQKRFDYKD 191 + R+ E A L++ LR + D P VI +++ +D Sbjct: 119 P--SIVTGLRPRIAELASALLDRLRAQRRP--DLVEGFAAPLPILVISALLG---IPEED 171 Query: 192 QNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEH 251 +L + G + TR + RE + Sbjct: 172 HTWLRANAVALQEASTTR-------------ARDGRGYARAEAASQEFTRYFRREVDRRG 218 Query: 252 QASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLL 311 D + + S +++ +VGT L AG ETT+ L +L Sbjct: 219 GDDRDDLL----------TLLVRARDTGSPLSVDGIVGTCVHLLTAGHETTTNFLAKAVL 268 Query: 312 LLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVT 371 L H +V +++ + T A V E+ RY V V Sbjct: 269 TLRAHRDVLDELRTTPES------------------TPAAVEELMRYDPPVQ-AVTRWAY 309 Query: 372 TDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAG 431 D + ++ IP+G+ ++ALL S D FP+P++ D ++ + F G Sbjct: 310 EDIRLGDHDIPRGSRVVALLGSANRDPARFPDPDVLDVHRAAERQ---------VGFGLG 360 Query: 432 KRICAGEGLARMELFLFLTTIL 453 C G LAR E + L +L Sbjct: 361 IHYCLGATLARAEAEIGLRALL 382 >3TKT-A nrPDB Length = 450 Score = 165 bits (418), Expect = 3e-41, Method: Composition-based stats. Identities = 73/405 (18%), Positives = 143/405 (35%), Gaps = 59/405 (14%) Query: 90 NGEEFSGRGNSPISQRITKGL-----GIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDR 144 F+ R +++ IT G ++ + + ++RR + + + ++ Sbjct: 97 KSTVFTLRVGEMMAKAITGGSPHLVESLVQMDAPKHPKLRRLTQDWFMPKNLAR--LDGE 154 Query: 145 VQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNEN 204 +++ A+ ++ + + P +V+ ++ + L L ++ Sbjct: 155 IRKIANEAIDRMLGAGEEGDFMALVAAPYPLHVVMQILGVP--PEDEPKMLFLTQQMFGG 212 Query: 205 FRILNSPWIQVCNNFPLLIDCFP--GTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRD 262 Q + + P V VA Y E + NP D Sbjct: 213 ---------QDEDMNKSGLKDLPPEQISQIVAGAVAEFERYFAGLAAERRR-----NPTD 258 Query: 263 FIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAK 322 + + + + + + G AG +TTS + L L + P++ A+ Sbjct: 259 DVATVIANAVVDGEP----MSDRDTAGYYIITASAGHDTTSASSAGAALALARDPDLFAR 314 Query: 323 VQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIP 382 V+ DR+ +P +V E R++ V + TDT+ I Sbjct: 315 VKA---------------DRNLLP---GIVEEAIRWTTPVQHFM-RTAATDTELCGQKIA 355 Query: 383 KGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLAR 442 G +M + HD +FP P FDP ++ + F AG C G LAR Sbjct: 356 AGDWLMLNYVAANHDPAQFPEPRKFDPTR---------PANRHLAFGAGSHQCLGLHLAR 406 Query: 443 MELFLFLTTILQNFN-LKSVDDLKNLNTTAVTKGIVSLPPSYQIC 486 +E+ + L +L + L+ + K +N+T G SLP ++ Sbjct: 407 LEMRVLLDVLLDRVDSLELAGEPKRVNST-FVGGFKSLPMRWKAA 450 >5DE9-A nrPDB Length = 410 Score = 164 bits (416), Expect = 6e-41, Method: Composition-based stats. Identities = 73/469 (15%), Positives = 143/469 (30%), Gaps = 91/469 (19%) Query: 31 PGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYF--GMNPIVVFHGYEAVKEALI 88 P P + + D T + GPV + G + ++ V+ L+ Sbjct: 11 PPVRDWPAV----DLPGSDFDPVLTELMRE-GPVTRISLPNGEGWAWLVTRHDDVR--LV 63 Query: 89 DNGEEF-----SGRGNSPISQRITKGLGII-SSNGKRWKEIRRFSLTTLRNFGMGKRSIE 142 N F R + ++ G + + +RR G+ Sbjct: 64 TNDPRFGREAVMDRQVTRLAPHFRPARGAVGFLDPPDHTRLRRSVAAAFTARGV------ 117 Query: 143 DRVQEEAHCLVEELRKTK---ASPCDPTF-ILGCAPCNVICSVVFQKRFDYKDQNFLTLM 198 +RV+E + +++EL P D T +L P VIC ++ D + T + Sbjct: 118 ERVRERSRGMLDELVDAMLRAGPPADLTEAVLSPFPIAVICELMGVPATDRHSMHTWTQL 177 Query: 199 KRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVN 258 + + ++ + +Y + + L + Sbjct: 178 ILSSSHGAEVSE------------------------RAKNEMNAYFSDLIG-----LRSD 208 Query: 259 NPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPE 318 + + + L + E + VG L + G E + LLL PE Sbjct: 209 SAGEDVTSLLGAAVG-----RDEITLSEAVGLAVLLQIGG-EAVTNNSGQMFHLLLSRPE 262 Query: 319 VTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSD-LVPTGVPHAVTTDTKFR 377 + +++ E + + E+ R+ G+ D + + Sbjct: 263 LAERLRSEPE------------------IRPRAIDELLRWIPHRNAVGLSRIALEDVEIK 304 Query: 378 NYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAG 437 I G + + D + FP+P+ D + + F G C G Sbjct: 305 GVRIRAGDAVYVSYLAANRDPEVFPDPDRIDFER---------SPNPHVSFGFGPHYCPG 355 Query: 438 EGLARMELFLFLTTILQN---FNLKSVDDLKNLNTTAVTKGIVSLPPSY 483 LAR+E L + +L L + A+ +G +LP ++ Sbjct: 356 GMLARLESELLVDAVLDRVPGLKLAVAPEDVPFKKGALIRGPEALPVTW 404 >6HQG-A nrPDB Length = 425 Score = 164 bits (415), Expect = 7e-41, Method: Composition-based stats. Identities = 74/443 (16%), Positives = 141/443 (31%), Gaps = 71/443 (16%) Query: 50 ICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKE-----ALIDNGEEFSGRGNSPISQ 104 + F K PV ++G++P GY +V + A+ N E FS + Sbjct: 37 MWPYFERLRKE-DPV---HWGVSPHEDVGGYWSVTKYNDIMAVDTNHEVFSSEPTIVLPD 92 Query: 105 RITKGLGIIS--SNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKAS 162 + + + R+ + + +E ++E A ++++L Sbjct: 93 PADDFTLPMFIAMDPPKHDVQRKTVQPIVAPNHLAY--LEPIIRERAGKILDDL--PIGE 148 Query: 163 PCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFP-- 220 + + + + +F F ++D+ LT W V + P Sbjct: 149 EINWVDKVSIELTTMTLATLFD--FPWEDRRKLT--------------FWSDVATSAPES 192 Query: 221 -LLIDCFPGTHNKVLKN-VALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQ 278 +L P H + + + Y E P+ + L E K+ Sbjct: 193 GILGTTDPEEHENLRRQTLFECVDYFMRLWNER----VNAPPKPDLISMLAHGESTKN-- 246 Query: 279 KSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPC 338 + +G + L V G +TT T+ +L L ++P+ K++E + Sbjct: 247 ---MDRMEYLGNLILLIVGGNDTTRNTISGSVLALHQNPDQDRKLRENPGLI-------- 295 Query: 339 MQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDD 398 A+V E R+ + + D + I +G + S D+ Sbjct: 296 ----------PAMVSETIRWQTPL-AYMRRRAKRDFELGGKTIREGDKVAMWYVSGNRDE 344 Query: 399 KEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNL 458 + PN + + + F G C G LA ++L + IL F Sbjct: 345 EVIDRPNDYWIER--------PRVRQHLSFGFGVHRCVGNRLAELQLKIIWEEILARFPR 396 Query: 459 KSVDDLKNLNTTAVTKGIVSLPP 481 V ++ KG LP Sbjct: 397 LEVVGPPRRVYSSFVKGYEELPV 419 >3RWL-A nrPDB Length = 426 Score = 160 bits (404), Expect = 1e-39, Method: Composition-based stats. Identities = 61/370 (16%), Positives = 113/370 (30%), Gaps = 58/370 (15%) Query: 110 LGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFI 169 I+ + R E R+ + + ++E ++E ++ L P Sbjct: 109 PNFIAMDRPRHDEQRKAVSPIVAPANLA--ALEGTIRERVSKTLDGL---------PVGE 157 Query: 170 LGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGT 229 V + Q D F K + +P V + Sbjct: 158 EFDWVDRVSIEITTQMLATLFDFPFEERRKLTRWSDVTTAAPGGGVVE-----------S 206 Query: 230 HNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVG 289 ++ + +Y + E +P + + L ++ E +G Sbjct: 207 WDQRKTELLECAAYFQVLWNER----VNKDPGNDLISMLAHSPATRN-----MTPEEYLG 257 Query: 290 TVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTD 349 V L V G +TT ++ G+L L K+P+ AK++ V + Sbjct: 258 NVLLLIVGGNDTTRNSMTGGVLALHKNPDQFAKLKANPALV------------------E 299 Query: 350 AVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDP 409 +V EI R+ + + D++ I KG ++ S DD+ P F Sbjct: 300 TMVPEIIRWQTPL-AHMRRTAIADSELGGKTIRKGDKVVMWYYSGNRDDEVIDRPEEFII 358 Query: 410 GHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNT 469 + + F G C G LA M+L + IL F+ V Sbjct: 359 DR--------PRPRQHLSFGFGIHRCVGNRLAEMQLRILWEEILTRFSRIEVMAEPERVR 410 Query: 470 TAVTKGIVSL 479 + +G + Sbjct: 411 SNFVRGYAKM 420 >1Q5D-A nrPDB Length = 419 Score = 157 bits (396), Expect = 1e-38, Method: Composition-based stats. Identities = 63/372 (16%), Positives = 125/372 (33%), Gaps = 53/372 (14%) Query: 108 KGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPT 167 K G+ + +R+ + + + + +Q L++ R + Sbjct: 91 KKYGLFGLPPEDHARVRKLVNPSFTSRAI--DLLRAEIQRTVDQLLDA-RSGQEEFDVVR 147 Query: 168 FILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFP 227 P I ++ L + +E FR S + L+ Sbjct: 148 DYAEGIPMRAISAL-------------LKVPAECDEKFRRFGSATARALGV--GLVPRVD 192 Query: 228 GTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENL 287 ++ +V + + + E + + N + L++ E + S + + L Sbjct: 193 EETKTLVASVTEGLALLHGVLDERRRNPLEN----DVLTMLLQAEADG----SRLSTKEL 244 Query: 288 VGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPY 347 V V + AGT+TT + + +L LL+ PE V+ E Sbjct: 245 VALVGAIIAAGTDTTIYLIAFAVLNLLRSPEALELVKAEPG------------------L 286 Query: 348 TDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIF 407 + E+ R+ +++ G D ++ I KG + L+ S L D F P++F Sbjct: 287 MRNALDEVLRFDNILRIGTVRFARQDLEYCGASIKKGEMVFLLIPSALRDGTVFSRPDVF 346 Query: 408 DPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNL 467 D + + + G +C G LAR+E + + TI + F + + Sbjct: 347 DVRR---------DTSASLAYGRGPHVCPGVSLARLEAEIAVGTIFRRFPEMKLKETPVF 397 Query: 468 NTTAVTKGIVSL 479 + I SL Sbjct: 398 GYHPAFRNIESL 409 >5FYF-A nrPDB Length = 470 Score = 157 bits (396), Expect = 1e-38, Method: Composition-based stats. Identities = 66/422 (15%), Positives = 133/422 (31%), Gaps = 64/422 (15%) Query: 61 YGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGI---ISSNG 117 +GP ++V + + V ++ FS + +GL + I+ + Sbjct: 102 FGPFWSVTRFEDILFVDKSHDL-----------FSAEPQIILGDP-PEGLSVEMFIAMDP 149 Query: 118 KRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNV 177 + R + + + +E ++ +++ L PT V Sbjct: 150 PKHDVQRSSVQGVVAPKNL--KEMEGLIRSRTGDVLDSL---------PTDKPFNWVPAV 198 Query: 178 ICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNV 237 + + TL+ E L ++ F + Sbjct: 199 SKELTG--------RMLATLLDFPYEERHKLVEWSDRMAGAASATGGEFADENAMFDDAA 250 Query: 238 ALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVA 297 + RS+ R + P + L ++ KD +G + L V Sbjct: 251 DMARSFSRLWRDKEARRAAGEEPGFDLISLLQSNKETKDLINRPM---EFIGNLTLLIVG 307 Query: 298 GTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQR 357 G +TT ++ GL+ + + P K++ + + + +V EI R Sbjct: 308 GNDTTRNSMSGGLVAMNEFPREFEKLKAKPELI------------------PNMVSEIIR 349 Query: 358 YSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNG 417 + + + D + I KG ++ S D+++F NP+ F +N Sbjct: 350 WQTPL-AYMRRIAKQDVELGGQTIKKGDRVVMWYASGNRDERKFDNPDQFIIDRKDARN- 407 Query: 418 NFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIV 477 M F G C G LA ++L + IL+ F+ V + + +G Sbjct: 408 -------HMSFGYGVHRCMGNRLAELQLRILWEEILKRFDNIEVVEEPERVQSNFVRGYS 460 Query: 478 SL 479 L Sbjct: 461 RL 462 >2RFC-A nrPDB Length = 343 Score = 156 bits (394), Expect = 2e-38, Method: Composition-based stats. Identities = 65/405 (16%), Positives = 125/405 (30%), Gaps = 79/405 (19%) Query: 76 VFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFG 135 + Y VK L+ N + FS + S G+ I+ + KE R S Sbjct: 14 HVYKYSDVKHVLM-NDKIFSSNPGNRYSN--AGGISFITMDNPEHKEFRDISAPYFLPSK 70 Query: 136 MGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFL 195 + D ++E ++ L++ + + P N+I ++ D Sbjct: 71 INDYK--DFIEETSNDLIKNIDNKD----IISEYAVRLPVNIISKILG---IPDSDMPLF 121 Query: 196 TLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASL 255 L + + + L++ F + ++ +A +K + Sbjct: 122 KLWSDYIIGNKRDENFNYVNNRMVSRLLEIFKSDSHGIINVLA------GSSLKNRK--- 172 Query: 256 DVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLK 315 ++ + + L + G ETT+ + + ++ + Sbjct: 173 --------------------------LTMDEKIKYIMLLIIGGNETTTNLIGNMIRVIDE 206 Query: 316 HPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTK 375 +P++ + V E RY + D+ Sbjct: 207 NPDIID---------------------DALKNRSGFVEETLRYYSPIQFLPHRFAAEDSY 245 Query: 376 FRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRIC 435 N I KG ++ L S D+ F P++F G + + F G +C Sbjct: 246 INNKKIKKGDQVIVYLGSANRDETFFDEPDLFKIGRR----------EMHLAFGIGIHMC 295 Query: 436 AGEGLARMELFLFLTTILQNFNLKSVDDLK-NLNTTAVTKGIVSL 479 G LAR+E + L IL +F +D K L + G L Sbjct: 296 LGAPLARLEASIALNDILNHFKRIKIDYKKSRLLDNKMVLGYDKL 340 >6HQW-A nrPDB Length = 445 Score = 152 bits (385), Expect = 2e-37, Method: Composition-based stats. Identities = 49/369 (13%), Positives = 107/369 (28%), Gaps = 60/369 (16%) Query: 112 IISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILG 171 I+ + RR M +E ++ +++ L D + Sbjct: 129 FIAMDRPDHTGQRRTVAPAFTPAKM--VEMEAEIRRRTASVLDSL--PWGERFDWVDKVS 184 Query: 172 CAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHN 231 + +++F F + D+ LT + + + Sbjct: 185 IELTTGMLAILFG--FPWADRRLLTFWSDWAGDVELT--------------------LAR 222 Query: 232 KVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTV 291 ++ + + + P + +I E + + + +G + Sbjct: 223 ELADTRFGFLGEMAHYFQRLWGARMQAPPSGDLISMMIHSEA-----MNHMSPQEFMGNL 277 Query: 292 ADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAV 351 L V G +TT T+ + L K P+ ++ + + Sbjct: 278 VLLIVGGNDTTRNTMSGIVHALDKFPDQRELLERDASLI------------------PNA 319 Query: 352 VHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGH 411 V E RY + + T DT+ I G ++ S D+ F NP+ Sbjct: 320 VQECIRYVTPL-AHMRRTATADTELFGNQIKAGEKVILWYISANRDETVFENPDKLMVDR 378 Query: 412 FLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTIL-QNFNLKSVDDLKNLNTT 470 + + F G C G LA ++L + L + + ++ +++ + Sbjct: 379 --------PNARRHLSFGHGIHRCVGARLAELQLRILLEEMHERRMRVRVAGEVERVR-A 429 Query: 471 AVTKGIVSL 479 G L Sbjct: 430 NFVHGFRKL 438 >2FR7-A nrPDB Length = 412 Score = 152 bits (383), Expect = 4e-37, Method: Composition-based stats. Identities = 59/370 (15%), Positives = 105/370 (28%), Gaps = 61/370 (16%) Query: 112 IISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILG 171 I+ ++ R L M + + D A ++EL + + Sbjct: 99 ILEADPPAHTRTRAVLSKVLSPATM--KRLRDGFAAAADAKIDELLARGGNIDAIADLAE 156 Query: 172 CAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHN 231 P +V F M E L V N F Sbjct: 157 AYPLSV----------------FPDAMGLKQEGRENLLPYAGLVFNAFGPP--------- 191 Query: 232 KVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTV 291 R E+ HQA + R + + E E V Sbjct: 192 ------NELRQSAIERSAPHQAYVAEQCQRPNLAPGGFGACIHAFSDTGEITPEEAPLLV 245 Query: 292 ADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAV 351 L AG +TT + + L + P+ A+++ + Sbjct: 246 RSLLSAGLDTTVNGIAAAVYCLARFPDEFARLRADPS------------------LARNA 287 Query: 352 VHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGH 411 E R+ V T D + I +G ++ L S D + + +P+ +D Sbjct: 288 FEEAVRFESPVQ-TFFRTTTRDVELAGATIGEGEKVLMFLGSANRDPRRWDDPDRYDITR 346 Query: 412 FLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTA 471 K+ + F +G +C G+ +AR+E + L + + + Sbjct: 347 ---------KTSGHVGFGSGVHMCVGQLVARLEGEVVLAALARKVAAIEIAGPLKRRFNN 397 Query: 472 VTKGIVSLPP 481 +G+ SLP Sbjct: 398 TLRGLESLPI 407 >5LIV-A nrPDB Length = 450 Score = 151 bits (382), Expect = 5e-37, Method: Composition-based stats. Identities = 72/396 (18%), Positives = 128/396 (32%), Gaps = 65/396 (16%) Query: 95 SGRGNSPISQRITK----GLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAH 150 + R + S R+ + G+ + G +RR + E V+ + Sbjct: 102 AYRDTATFSTRMFQAGILNGGLAAMQGDEHARMRR-VYNMFFLPRAVSQYEERFVRPISE 160 Query: 151 CLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNS 210 +V+ L P VI + + +E R + Sbjct: 161 QVVDRLAGKPRVDL-LEDFAMELPRRVIGELFGFP---------AEKLHETDERVRAMLR 210 Query: 211 PWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIK 270 +++ + P + + T I E V+ RD D L + Sbjct: 211 GLVRMHD---------PAAVAESQRAYGETLGLITEVVER--------ESRDTSDTLLGE 253 Query: 271 MEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHV 330 + + + + IE V L + G ETTS + + LL HP+ A+V+++ Sbjct: 254 ILRTLKAEHMD-TIEASRQIVLSLILGGYETTSWLVANTIHALLAHPDTLARVRQDPS-- 310 Query: 331 IGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMAL 390 A + E R+ GV V D + + + GT + Sbjct: 311 ----------------LLPAAIEEGMRWCP-SSFGVLRMVERDVRLDDQALSAGTVVCLA 353 Query: 391 LTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLT 450 + +D+ +P+P ++D K F G C G LARME + L Sbjct: 354 GIAGNYDETAYPSPEVYDIDR--------KPLPAANVFGGGAHFCVGAPLARMEARVGLQ 405 Query: 451 TILQNFN-LKSVDDLKNL----NTTAVTKGIVSLPP 481 +L F L++V + + +V G LP Sbjct: 406 ALLARFPGLRAVPEERPSFMYGAKDSVAHGPDKLPV 441 >6F88-A nrPDB Length = 400 Score = 151 bits (381), Expect = 7e-37, Method: Composition-based stats. Identities = 72/396 (18%), Positives = 128/396 (32%), Gaps = 65/396 (16%) Query: 95 SGRGNSPISQRITK----GLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAH 150 + R + S R+ + G+ + G +RR + E V+ + Sbjct: 52 AYRDTATFSTRMFQAGILNGGLAAMQGDEHARMRR-VYNMFFLPRAVSQYEERFVRPISE 110 Query: 151 CLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNS 210 +V+ L P VI + + +E R + Sbjct: 111 QVVDRLAGKPRVDL-LEDFAMELPRRVIGELFGFP---------AEKLHETDERVRAMLR 160 Query: 211 PWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIK 270 +++ + P + + T I E V+ RD D L + Sbjct: 161 GLVRMHD---------PAAVAESQRAYGETLGLITEVVER--------ESRDTSDTLLGE 203 Query: 271 MEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHV 330 + + + + IE V L + G ETTS + + LL HP+ A+V+++ Sbjct: 204 ILRTLKAEHMD-TIEASRQIVLSLILGGYETTSWLVANTIHALLAHPDTLARVRQDPS-- 260 Query: 331 IGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMAL 390 A + E R+ GV V D + + + GT + Sbjct: 261 ----------------LLPAAIEEGMRWCP-SNFGVLRMVERDVRLDDQALSAGTVVCLA 303 Query: 391 LTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLT 450 + +D+ +P+P ++D K F G C G LARME + L Sbjct: 304 GIAGNYDETAYPSPEVYDIDR--------KPLPAANVFGGGAHFCVGAPLARMEARVGLQ 355 Query: 451 TILQNFN-LKSVDDLKNL----NTTAVTKGIVSLPP 481 +L F L++V + + +V G LP Sbjct: 356 ALLARFPGLRAVPEERPSFMYGAKDSVAHGPDKLPV 391 >5HH3-A nrPDB Length = 397 Score = 151 bits (380), Expect = 9e-37, Method: Composition-based stats. Identities = 65/422 (15%), Positives = 122/422 (28%), Gaps = 81/422 (19%) Query: 70 GMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGK-RWKEIRRFSL 128 G + GY+ +++ L + ++FS R + G ++ +RR Sbjct: 50 GGRTAWLATGYDEIRQVL--SSDDFSARLLYGGTAAGITWPGFLTQYDPPEHTRLRRMVA 107 Query: 129 TTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAP-CNVICSVVFQKRF 187 M + + +V+ ++ + P D G + C + R Sbjct: 108 PAFAVRRM--QKFQPQVERVVQDSLDAIEALGG-PVDFVPRFGWSVATTATCDFLGIPRD 164 Query: 188 DYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREK 247 D D L + + +Y+ + Sbjct: 165 DQADLAR-------------------------SLHASRTERSGKRRTAAGNKFMTYMNKM 199 Query: 248 VKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLR 307 + +P D + +++ E L G A + AG + + L Sbjct: 200 TARTRR-----DPGDDMFGVVVR------EYGDEITDAELTGVAAFVMGAGADQVARFLA 248 Query: 308 YGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVP 367 G L+ PE A ++E+ D V + E+ RY P Sbjct: 249 AGAWLMADDPEQFALLREKPDTVPDW------------------LDEVIRYLTTDEKTHP 290 Query: 368 HAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNP-NIFDPGHFLDKNGNFKKSDYFM 426 T D + ++LI G T+ L + + FP P + FD + + Sbjct: 291 RVATDDVRIGDHLIKAGDTVTCSLLAANR--RNFPRPEDRFDITRVRPE---------HL 339 Query: 427 PFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQIC 486 F G C G LA + + + F L + I PP + + Sbjct: 340 AFGHGIHHCLGRSLAELVFRTAIPALAHRF--------PTLRLAEPHREIRLGPPPFDVE 391 Query: 487 FI 488 + Sbjct: 392 AL 393 >5DQN-A nrPDB Length = 426 Score = 150 bits (379), Expect = 1e-36, Method: Composition-based stats. Identities = 66/406 (16%), Positives = 127/406 (31%), Gaps = 77/406 (18%) Query: 76 VFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLG---------IISSNGKRWKEIRRF 126 + + VKE + F + I +++ + + +R+ Sbjct: 55 LVTKHADVKEV-SRRSDVFGSSPDGAIPVYPQDMTREAVDLQRAVLLNMDAPQHTRLRKI 113 Query: 127 SLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGC-APCNVICSVVFQK 185 +G+ +ED ++ A + D + C P I ++ Sbjct: 114 ISRGFTPRAIGR--LEDELRSRAQKI--AQTAAAQGAGDFVEQVSCELPLQAIAELLGVP 169 Query: 186 RFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIR 245 + D K F + + + + P + SY Sbjct: 170 QDDRD--------KLFRWSNEMTAGEDPEYADVDPAMSSF-------------ELISYAM 208 Query: 246 EKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTT 305 + +E NP + I LI E D + + + V L VAG ETT + Sbjct: 209 KMAEER-----AVNPTEDIVTKLI----EADIDGEKLSDDEFGFFVVMLAVAGNETTRNS 259 Query: 306 LRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTG 365 + +G++ ++P+ ++E + EI R++ V + Sbjct: 260 ITHGMIAFAQNPDQWELYKKERP--------------------ETAADEIVRWATPV-SA 298 Query: 366 VPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYF 425 D + I KG ++ S D++ F +P+ F+ + Sbjct: 299 FQRTALEDVELGGVQIKKGQRVVMSYRSANFDEEVFEDPHTFNILR---------SPNPH 349 Query: 426 MPFSA-GKRICAGEGLARMELFLFLTTILQNF-NLKSVDDLKNLNT 469 + F G C G LARM + L I N +LK + + L + Sbjct: 350 VGFGGTGAHYCIGANLARMTINLIFNAIADNMPDLKPIGAPERLKS 395 >2NZA-A nrPDB Length = 413 Score = 149 bits (377), Expect = 2e-36, Method: Composition-based stats. Identities = 78/480 (16%), Positives = 142/480 (29%), Gaps = 89/480 (18%) Query: 19 LWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYF--GMNPIVV 76 + + PP P L +D + + GP+ V G + Sbjct: 2 TQETTTLTGQSPPPVRDWP----ALDLDGPEFDPVLAELMRE-GPLTRVRLPHGEGWAWL 56 Query: 77 FHGYEAVKEALIDNGEEFSGRGNSPISQRIT-------KGLGIISSNGKRWKEIRRFSLT 129 Y+ VK I N F GR Q + + ++ +RR Sbjct: 57 ATRYDDVKA--ITNDPRF-GRAEVTQRQITRLAPHFKPRPGSLAFADQPDHNRLRRAVAG 113 Query: 130 TLRNFGMGK-RSIEDRVQEEAHCLVEELRKTKASPCDPTF-ILGCAPCNVICSVVFQKRF 187 F +G + + R QE LV+ + P D +L P V+ V+ Sbjct: 114 A---FTVGATKRLRPRAQEILDGLVDGILAE-GPPADLVERVLEPFPIAVVSEVMGVPAA 169 Query: 188 DYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREK 247 D + + + +I+++ G + +I E Sbjct: 170 DRE--------RVHSWTRQIISTS----------------GGAEAAERAKRGLYGWITET 205 Query: 248 VKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLR 307 V+ S + L + ++ VG L + G E + + Sbjct: 206 VRARAGSE-----GGDVYSMLGAAVGRGEVGET-----EAVGLAGPLQIGG-EAVTHNVG 254 Query: 308 YGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSD-LVPTGV 366 L LLL E+ A+++E + E+ R+ G+ Sbjct: 255 QMLYLLLTRRELMARMRERPGA------------------RGTALDELLRWISHRTSVGL 296 Query: 367 PHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFM 426 D + I G + + D FP+P+ D + + Sbjct: 297 ARIALEDVEVHGTRIAAGEPVYVSYLAANRDPDVFPDPDRIDLDR---------DPNPHL 347 Query: 427 PFSAGKRICAGEGLARMELFLFLTTILQN---FNLKSVDDLKNLNTTAVTKGIVSLPPSY 483 + G C G LARM+ L + T+L+ L + + +G +LP ++ Sbjct: 348 AYGNGHHFCTGAVLARMQTELLVDTLLERLPGLRLAVPAEQVAWRRKTMIRGPRTLPCTW 407 >1F4U-A nrPDB Length = 368 Score = 149 bits (376), Expect = 3e-36, Method: Composition-based stats. Identities = 58/362 (16%), Positives = 114/362 (31%), Gaps = 77/362 (21%) Query: 110 LGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFI 169 +++S+ E+R S + +++E ++E L++ + + D Sbjct: 66 YTMLTSDPPLHDELRSMSADIFSPQKL--QTLETFIRETTRSLLDSIDPRED---DIVKK 120 Query: 170 LGCA-PCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPG 228 L P VI ++ D ++F E ++ + F L Sbjct: 121 LAVPLPIIVISKILGLPIEDK---------EKFKEWSDLVAFRLGKPGEIFELGKKYLE- 170 Query: 229 THNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLV 288 + VK+H S E S + + Sbjct: 171 ---------------LIGYVKDHLNS---------------GTEVVSRVVNSNLSDIEKL 200 Query: 289 GTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYT 348 G + L +AG ETT+ + ++ + + +++EE Sbjct: 201 GYIILLLIAGNETTTNLISNSVIDFTRF-NLWQRIREE-------------------NLY 240 Query: 349 DAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFD 408 + E RYS V V K + I +G + + S D++ F + F Sbjct: 241 LKAIEEALRYSPPVMRTV-RKTKERVKLGDQTIEEGEYVRVWIASANRDEEVFHDGEKFI 299 Query: 409 PGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFN-LKSVDDLKNL 467 P + + F +G +C G LAR+E + + + F ++ +D K Sbjct: 300 PDR---------NPNPHLSFGSGIHLCLGAPLARLEARIAIEEFSKRFRHIEILDTEKVP 350 Query: 468 NT 469 N Sbjct: 351 NE 352 >4DO1-A nrPDB Length = 410 Score = 149 bits (375), Expect = 3e-36, Method: Composition-based stats. Identities = 76/459 (16%), Positives = 133/459 (28%), Gaps = 73/459 (15%) Query: 30 PPGPTPLPIIG-NMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALI 88 PP + +P + + +D D + GPV VY + Y V L Sbjct: 13 PPNDSTIPHLAIDPFSLDFFDDPYPDQQTLRDAGPV--VYLDKWNVYGVARYAEVHAVLN 70 Query: 89 DNGEEFSGRG----NSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDR 144 D S RG + + I+ ++ R L M ++I D Sbjct: 71 DPTTFCSSRGVGLSDFKKEKPWRPPSLILEADPPAHTRPRAVLSKVLSPATM--KTIRDG 128 Query: 145 VQEEAHCLVEEL--RKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFN 202 A V+EL R + D + F M Sbjct: 129 FAAAADAKVDELLQRGCIDAIADLAEAYPLSV-------------------FPDAMGLKQ 169 Query: 203 ENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRD 262 E L V N F R E+ HQA ++ R Sbjct: 170 EGREHLLPYAGLVFNAFGPP---------------NELRQTAIERSAPHQAYVNEQCQRP 214 Query: 263 FIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAK 322 + E + V L AG +TT + + L + P + Sbjct: 215 NLAPGGFGACIHAFTDTGEITPDEAPLLVRSLLSAGLDTTVNGIGAAVYCLARFPGELQR 274 Query: 323 VQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIP 382 ++ + E R+ V T + + +I Sbjct: 275 LRSDP------------------TLARNAFEEAVRFESPVQ-TFFRTTTREVELGGAVIG 315 Query: 383 KGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLAR 442 +G ++ L S D + + +P+++D K+ + F +G +C G+ +AR Sbjct: 316 EGEKVLMFLGSANRDPRRWSDPDLYDITR---------KTSGHVGFGSGVHMCVGQLVAR 366 Query: 443 MELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPP 481 +E + L+ + + +D +G+ SLP Sbjct: 367 LEGEVMLSALARKVAAIDIDGPVKRRFNNTLRGLESLPV 405 >2X9P-A nrPDB Length = 404 Score = 147 bits (371), Expect = 1e-35, Method: Composition-based stats. Identities = 69/457 (15%), Positives = 135/457 (29%), Gaps = 86/457 (18%) Query: 43 LQIDVKDICKS--FTNFSKVYGPVFTVYF-GMNPIVVFHGYEAVKEALIDNGEEFSGRGN 99 L ++ + K + GP+ V + + + +K+ L D + + Sbjct: 18 LNLEPPKMLKLSPLLRALQDRGPIHRVRTPAGDEAWLVTRHAELKQLLHDERIGRTH-PD 76 Query: 100 SPISQRITKGL--------GIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHC 151 P + + + S ++ E RR + ++ +V+E A Sbjct: 77 PPSAAQYVRSPFLDLLISDADAESGRRQHAETRRLLTPLFSARRVL--EMQPKVEEAADT 134 Query: 152 LVEELRKTKASPCDPTFILGCA-PCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNS 210 L++ + P D L V+C V+ + TL+ + Sbjct: 135 LLDAFIA-QGPPGDLHGELTVPFALTVLCEVIGVP--PQRRAELTTLLAGIAKL------ 185 Query: 211 PWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIK 270 ++ Y+ V+ +A P I L Sbjct: 186 -----------------DDREGAVRAQDDLFGYVAGLVEHKRA-----EPGPDIISRL-- 221 Query: 271 MEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHV 330 E + + L AG ++ ++ + G++LL HP+ A + D Sbjct: 222 -------NDGELTEDRVAHLAMGLLFAGLDSVASIMDNGVVLLAAHPDQRAAALADPD-- 272 Query: 331 IGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVP-HAVTTDTKFRNYLIPKGTTIMA 389 V E+ R + + +P + D +F I G ++ Sbjct: 273 ----------------VMARAVEEVLRTARAGGSVLPPRYASEDMEFGGVTIRAGDLVLF 316 Query: 390 LLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFL 449 L D++ F P FD + + + F G C G LAR+EL Sbjct: 317 DLGLPNFDERAFTGPEEFD---------AARTPNPHLTFGHGIWHCIGAPLARLELRTMF 367 Query: 450 TTILQN---FNLKSVDDLKNLNTTAVTKGIVSLPPSY 483 T + + + L ++ G L + Sbjct: 368 TKLFTRLPELRPELPVEQLRLKEGQLSGGFAELRVVW 404 >1UE8-A nrPDB Length = 367 Score = 147 bits (370), Expect = 1e-35, Method: Composition-based stats. Identities = 56/330 (16%), Positives = 109/330 (33%), Gaps = 46/330 (13%) Query: 152 LVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSP 211 L +ELR A +P+ + V ++ D+ F + ++ S Sbjct: 75 LHDELRNLTADAFNPSNLPVDFVREVTVKLL-----SELDEEFDVIESFAIPLPILVISK 129 Query: 212 WIQVCNNFPLLID--CFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLI 269 + + + + D + E + + LD ++ +D Sbjct: 130 MLGINPDVKKVKDWSDLVALRLGRADEIFSIGRKYLELISFSKKELDSRKGKEIVD---- 185 Query: 270 KMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDH 329 + ++ SE E G L +AG ETT+ + + + V+E+ Sbjct: 186 LTGKIANSNLSELEKE---GYFILLMIAGNETTTNLIGNAIEDFTLY-NSWDYVREKGAL 241 Query: 330 VIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMA 389 V E R+S V + K R+ +I +G + Sbjct: 242 K--------------------AVEEALRFSPPVMRTI-RVTKEKVKIRDQVIDEGELVRV 280 Query: 390 LLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFL 449 + S D++ F +P+ F P + + F +G +C G LAR+E + L Sbjct: 281 WIASANRDEEVFKDPDSFIPDR---------TPNPHLSFGSGIHLCLGAPLARLEARIAL 331 Query: 450 TTILQNFNLKSVDDLKNLNTTAVTKGIVSL 479 + F +K + + ++ V G L Sbjct: 332 EEFAKKFRVKEIVKKEKID-NEVLNGYRKL 360 >5H1Z-A nrPDB Length = 407 Score = 146 bits (368), Expect = 2e-35, Method: Composition-based stats. Identities = 50/375 (13%), Positives = 116/375 (30%), Gaps = 60/375 (16%) Query: 108 KGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPT 167 + I+ + + RR M + D ++ +++ L +P D Sbjct: 87 RMPMFIAMDRPKHTGQRRTVAPAFTPSEM--VRMSDNIRMRTAEVLDSLE--WNTPFDWV 142 Query: 168 FILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFP 227 + + +++F F ++++ LT + + ++ + Sbjct: 143 DTVSVELTTQMLAILFD--FPWEERRKLTFWSDWAGDIELVKN----------------E 184 Query: 228 GTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENL 287 + L+++ Y + + P + +I + +E + Sbjct: 185 ELRLERLRHMYECGGYFQNLWN----AKIGKPPTPDLISMMIH-----SDAMAEMDQMEF 235 Query: 288 VGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPY 347 +G + L V G +TT T+ L P+ AK++ + + Sbjct: 236 LGNLILLIVGGNDTTRNTMSAVAYGLDLFPDQRAKLEADPSMI----------------- 278 Query: 348 TDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIF 407 V EI R+ + + T D++ I G + S D+ F N + Sbjct: 279 -PNTVQEIIRWQTPL-AHMRRTATVDSELEGQQIKAGDKLALWYISANRDESVFENADRI 336 Query: 408 DPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTIL-QNFNLKSVDDLKN 466 + + F G C G LA +++ + L + + + + + + Sbjct: 337 IVDR--------PNARRHLAFGHGIHRCVGARLAELQIAVLLEEMAKRRMRVNVLGEPER 388 Query: 467 LNTTAVTKGIVSLPP 481 + G LP Sbjct: 389 V-AACFVHGYRKLPV 402 >4PWV-A nrPDB Length = 446 Score = 144 bits (363), Expect = 8e-35, Method: Composition-based stats. Identities = 69/428 (16%), Positives = 136/428 (31%), Gaps = 80/428 (18%) Query: 69 FGMNPIV-VFHGYEAVKEALIDNGEEFSGRGNSPISQRITK----GLGIISSNGKRWKEI 123 G P V Y V DN + S +GN ++ G + ++G + + Sbjct: 70 VGDAPGFWVVSRYADVMALYKDNKKLTSEKGNVLVTLLAGGDSAAGKMLAVTDGAMHRGL 129 Query: 124 RRFSLTTLRNFGMGKRSIEDRVQEE----AHCLVEELRKTKASPCDPT-FILGCAPCNVI 178 R L + ++++ V + +V+ R+ + CD + P N I Sbjct: 130 RNVLLKSF-----SPQALKPIVDQIRVNTTRLVVDAARRGE---CDFAADVAEQIPLNTI 181 Query: 179 CSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVA 238 ++ D+ FL + + + + T + +N Sbjct: 182 SDLLG---VPAADREFLLKLNKSALSSEDADQS----------------ATDAWLARNEI 222 Query: 239 LTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAG 298 L Y E V E +A P + + L + E +V L + G Sbjct: 223 LL--YFSELVAERRA-----KPTEDVISVLANSMVDGKP----LTEEVIVLNCYSLILGG 271 Query: 299 TETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRY 358 ET+ ++ + ++P+ +++ ++ E+ R+ Sbjct: 272 DETSRLSMIDSVQTFTQYPDQWELLRDGKVT------------------LESATEEVLRW 313 Query: 359 SDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGN 418 + AVT D + +I G + S D++ F +P FD Sbjct: 314 ATPAMHFGRRAVT-DMELHGQVIAAGDVVTLWNNSANRDEEVFADPYAFDLNR------- 365 Query: 419 FKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFN--LKSVDDLKNLNTTAVTKGI 476 + + F G C G L R E+ L L+ + + + + + + G+ Sbjct: 366 --SPNKHITFGYGPHFCLGAYLGRAEVHALLDA-LRTYTTGFEITGEPQRI-HSNFLTGL 421 Query: 477 VSLPPSYQ 484 LP Q Sbjct: 422 SRLPVRIQ 429 >6G5O-A nrPDB Length = 399 Score = 143 bits (361), Expect = 1e-34, Method: Composition-based stats. Identities = 76/417 (18%), Positives = 134/417 (32%), Gaps = 76/417 (18%) Query: 105 RITKGLGIISSNGK------RWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAH-------- 150 R +KG G ++ R K++R+ + + F G + E Sbjct: 14 RESKGYGEMNDQDDPVTMLLRHKDVRKSAHN-YKTFQSGAVPGRIVIPSEVDIRDTRQIP 72 Query: 151 ------------CLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM 198 +VE K + L ++ + + + L L Sbjct: 73 FEVDPPVHGVYRAIVEPWFKRPLQ-AEYQEKLTAQISEIVEETLLKGSVEVVTDFALRLQ 131 Query: 199 KRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVA-LTRSYIREKVKEHQASLDV 257 R +LN+P+ + F + + A + YI E++ Sbjct: 132 SRALTL--LLNTPFSESETWISWGTHVFRSEGEALDGDKANILYHYIDEQIDRASE---- 185 Query: 258 NNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHP 317 NP D + L+ E E + E + G + F G +T + + L +HP Sbjct: 186 -NPGDDMYSVLLNSEFEG----RKLTKEEVKGVMVLTFAGGRDTVINAVTNSIAYLAEHP 240 Query: 318 EVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFR 377 E ++++E + T V E+ RY + T + VT DT Sbjct: 241 EALERLRKEPE------------------ITGRAVEEMIRYFSPL-TQMGRVVTEDTHVC 281 Query: 378 NYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAG 437 + + + I S D F NPN K + + F C G Sbjct: 282 EHAVKADSRISLCWASANRDAAVFENPNEIVLDR---------KVNPHVGFGFSHHNCLG 332 Query: 438 EGLARMELFLFLTTILQN---FN-LKSVDDLKNLNTTAVTKGIVSLPPSYQICFIPV 490 AR L + L T+ Q F L +++++L+ G ++ QI F P+ Sbjct: 333 ATHARQILKILLQTLAQKVASFEILDYKENIEDLDHFQRKVGFHNI----QIKFNPL 385 >5HDI-A nrPDB Length = 404 Score = 142 bits (359), Expect = 2e-34, Method: Composition-based stats. Identities = 58/369 (15%), Positives = 110/369 (29%), Gaps = 60/369 (16%) Query: 112 IISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCL-VEELRKTKASPCDPTFIL 170 + +++ R+ L L + R +E + A L V+ ++ + Sbjct: 90 LATADDPAHAVHRKLVLRHLAAKRI--RVMEQFTVQAADRLWVDGMQD--GCIEWMGAMA 145 Query: 171 GCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTH 230 P V+ ++ D + L+K ++L + Sbjct: 146 NRLPMMVVAELIGLP-----DPDIAQLVKWGYAATQLLEGLVENDQLVAAGV-------- 192 Query: 231 NKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGT 290 + YI E+ A +PRD + L E + Sbjct: 193 -----ALMELSGYIFEQFDRAAA-----DPRDNLLGELATACASG-----ELDTLTAQVM 237 Query: 291 VADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDA 350 + LF AG E+T+ L + +L P++ +V+ + A Sbjct: 238 MVTLFAAGGESTAALLGSAVWILATRPDIQQQVRANPE------------------LLGA 279 Query: 351 VVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPG 410 + E RY H T +P + ++ L + D +F P F Sbjct: 280 FIEETLRYEPPFRGHYRHVRNA-TTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLD 338 Query: 411 HFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTT 470 + F G C G LAR+E + L +L ++ D+ + Sbjct: 339 RA--------GGKGHISFGKGAHFCVGAALARLEARIVLRLLLDRTSVIEAADVGGWLPS 390 Query: 471 AVTKGIVSL 479 + + I L Sbjct: 391 ILVRRIERL 399 >2UUQ-A nrPDB Length = 414 Score = 140 bits (353), Expect = 1e-33, Method: Composition-based stats. Identities = 55/377 (14%), Positives = 116/377 (30%), Gaps = 61/377 (16%) Query: 106 ITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCD 165 + ++ + E R+ + ++E V++ +E+LR Sbjct: 90 LHDTPPMVMQDPPVHTEFRKLVSRGFTPRQV--ETVEPTVRKFVVERLEKLRANGGGDI- 146 Query: 166 PTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDC 225 T + P V+ + D+ + W Q + Sbjct: 147 VTELFKPLPSMVVAHYLGVPEEDWTQFD-----------------GWTQAIVAANAVD-- 187 Query: 226 FPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIE 285 G L V +Y ++ + P D L+ D + Sbjct: 188 --GATTGALDAVGSMMAYFTGLIERRR-----TEPADDAISHLVAAGVGADGDTAGTL-- 238 Query: 286 NLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHM 345 +++ + G +T + L + LL + P+ + ++ + + Sbjct: 239 SILAFTFTMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPD------------- 285 Query: 346 PYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEF-PNP 404 V E+ R + V G+ T D + IP G ++ L S D++++ P+ Sbjct: 286 -----AVEELLRLTSPVQ-GLARTTTRDVTIGDTTIPAGRRVLLLYGSANRDERQYGPDA 339 Query: 405 NIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF-NLKSVDD 463 D + FS G C G ARM+ + LT +L + + + Sbjct: 340 AELDVTRC---------PRNILTFSHGAHHCLGAAAARMQCRVALTELLARCPDFEVAES 390 Query: 464 LKNLNTTAVTKGIVSLP 480 + + + +S+P Sbjct: 391 RIVWSGGSYVRRPLSVP 407 >3IVY-A nrPDB Length = 433 Score = 140 bits (353), Expect = 1e-33, Method: Composition-based stats. Identities = 63/361 (17%), Positives = 120/361 (33%), Gaps = 67/361 (18%) Query: 112 IISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILG 171 +++ + +R+ +G+ + D +QE A + A D + Sbjct: 116 MLNMDAPHHTRLRKIISRGFTPRAVGR--LHDELQERAQKI--AAEAAAAGSGDFVEQVS 171 Query: 172 C-APCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTH 230 C P I ++ + D K F+ + + N P P Sbjct: 172 CELPLQAIAGLLGVPQEDRG--------KLFHWSNEMTG-------NEDPEYAHIDPKAS 216 Query: 231 NKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGT 290 + A Y + +E NP D I LI+ + + + + + + Sbjct: 217 S------AELIGYAMKMAEEK-----AKNPADDIVTQLIQADIDGE----KLSDDEFGFF 261 Query: 291 VADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDA 350 V L VAG ETT ++ G++ +HP+ + +++ + Sbjct: 262 VVMLAVAGNETTRNSITQGMMAFAEHPDQWE-LYKKVRP-------------------ET 301 Query: 351 VVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPG 410 EI R++ V T D + I KG ++ S D++ F +P F+ Sbjct: 302 AADEIVRWATPV-TAFQRTALRDYELSGVQIKKGQRVVMFYRSANFDEEVFQDPFTFNIL 360 Query: 411 HFLDKNGNFKKSDYFMPFSA-GKRICAGEGLARMELFLFLTTILQNF-NLKSVDDLKNLN 468 + + F G C G LARM + L + + +LK + + L Sbjct: 361 R---------NPNPHVGFGGTGAHYCIGANLARMTINLIFNAVADHMPDLKPISAPERLR 411 Query: 469 T 469 + Sbjct: 412 S 412 >6HQD-A nrPDB Length = 420 Score = 140 bits (353), Expect = 1e-33, Method: Composition-based stats. Identities = 61/454 (13%), Positives = 138/454 (30%), Gaps = 75/454 (16%) Query: 45 IDVKDICKSFTNFSKV----------YGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEF 94 + + F + YGP +++ + + + + + + Sbjct: 29 FERDGLHPYFERLRREDPVHYCKASEYGPYWSITKFSDIVAI----DTNHKVFSSDHTNG 84 Query: 95 SGRGNSPISQRITKGL---GIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHC 151 S + + G+ + + + R + + + E ++E Sbjct: 85 SFVLDDTTLNAVDGGIYLPNFLGMDPPKHDVHRMVVSPIVAPQNLLR--FEATIRERTKR 142 Query: 152 LVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSP 211 ++ EL P V + D F K + I P Sbjct: 143 VLSEL---------PIGEEFNWVDRVSIELTTMMLATLLDFPFDDRRKLTRWSDIITTRP 193 Query: 212 WIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKM 271 + + + + + +Y + E QA P+ + L Sbjct: 194 GYGLVD-----------SWEQRESELMECLAYFQRLYAERQAM----PPKPDLISMLAHS 238 Query: 272 EQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVI 331 + +D ++F +GT+A L V G +TT +++ + +P+ KV+ Sbjct: 239 PEMQDLTPTDF-----LGTLALLIVGGNDTTRSSMSGSAMACHLYPQEFDKVR------- 286 Query: 332 GRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALL 391 ++ +V+ E+ R+ + + D +FR I KG ++ Sbjct: 287 -----------NNRALLASVIPEVVRWQTPI-AHMRRTALEDVEFRGKQIRKGDKVVMWY 334 Query: 392 TSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTT 451 S DD+ P F ++ + + F G C G LA ++L + Sbjct: 335 LSGNRDDEVIDRPMDFIADR--------PRARHHLSFGFGIHRCLGNRLAELQLKILWEE 386 Query: 452 ILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQI 485 + + ++ V + + G + +P Sbjct: 387 MCERYSRIEVCGEPVRVPSNLVHGYIDIPVRLHA 420 >5EX8-A nrPDB Length = 424 Score = 139 bits (350), Expect = 2e-33, Method: Composition-based stats. Identities = 61/413 (14%), Positives = 119/413 (28%), Gaps = 79/413 (19%) Query: 78 HGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGK-RWKEIRRFSLTTLRNFGM 136 G + V++ L ++FS R + G ++ +RR + + M Sbjct: 85 TGIDEVRQVL--GSDKFSARLLYGGTAAGITWPGFLTQYDPPEHTRLRRMVVPAFSHRRM 142 Query: 137 GKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCN-VICSVVFQKRFDYKDQNFL 195 + RV++ ++ + ++ P D G A C + R D D + Sbjct: 143 --QKFRPRVEQIVQDSLDTI-ESLGGPVDFVPHFGWAIATPATCDFLGIPRDDQADLARI 199 Query: 196 TLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASL 255 L R + + + +Y+++ V + + Sbjct: 200 LLASRTD-------------------------RSDKRRTAAGNKFMTYMKQHVAQSRRGS 234 Query: 256 DVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLK 315 D + + L G A + A + + L G L+++ Sbjct: 235 -----GDDLFGIV------GRENGDAITDAELTGVAAFVMGAAADQVARLLAAGAWLMVE 283 Query: 316 HPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTK 375 P A ++E+ + V P D E RY P T D + Sbjct: 284 QPAQFALLREKPETV------PEWLD------------ETMRYLTTDEKTHPRVATQDVR 325 Query: 376 FRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRIC 435 N L+ G T+ L + + FD + + F G C Sbjct: 326 IGNQLVKAGDTVTCSLLAANR-PNYPSAEDEFDITR---------EKAEHLAFGHGIHHC 375 Query: 436 AGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFI 488 G +A + + + + F L + I PP + + + Sbjct: 376 LGRAMAELMFKVSIPALAHRF--------PTLRLADPQREITLGPPPFDVEAL 420 >6GII-A nrPDB Length = 479 Score = 137 bits (345), Expect = 1e-32, Method: Composition-based stats. Identities = 67/420 (15%), Positives = 129/420 (30%), Gaps = 71/420 (16%) Query: 51 CKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNG--------EEFSGRGNSPI 102 F +++ P+F Y V Y+ +K+ D + F+ + ++ + Sbjct: 80 PAQFVRWAREQVPIF--YAPKLNYWVVTRYDTIKQIFRDPVTFSPSNVLQSFA-QPSAEV 136 Query: 103 SQRITK-----GLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELR 157 Q + + +++ + E RR + + + + E V+E V Sbjct: 137 RQVLERYGYAFNRTLVNEDEPMHLERRRVLMEPFASEHLAEH--EPMVRELVRRAVNRFI 194 Query: 158 KTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCN 217 T + +I V F FL + E R + + Sbjct: 195 DTGRADL---------VDQMIWEVPFTVALH-----FLGVDDDDREKMRRF-----AIAH 235 Query: 218 NFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDN 277 P V + V + E +++ + + D + +++ Sbjct: 236 TVNAFGRPSPEEQLAVAETVGQFWQFCGEVLEKMRRTADGPGW-------MRYSIRQQKL 288 Query: 278 QKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSP 337 L + + VA ETT L LL+H V ++ + + Sbjct: 289 YPDVVTDSYLHSMMQAIIVAAHETTVFATTNALKTLLEHETVWREICADPSLI------- 341 Query: 338 CMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHD 397 A E RY+ V G T + + +P G I+ ++ S HD Sbjct: 342 -----------PAAAEECLRYNGPV-AGWRRRTTREVEVEGVRLPVGANILMVVASANHD 389 Query: 398 DKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFN 457 F +P FD G + + F G C G L RME+ + + + + Sbjct: 390 SAHFDDPEFFDIGR--------SNASEHLNFGYGAHQCLGRNLGRMEMQIMIEELSRRLP 441 >5HIW-A nrPDB Length = 398 Score = 137 bits (345), Expect = 1e-32, Method: Composition-based stats. Identities = 73/415 (17%), Positives = 139/415 (33%), Gaps = 71/415 (17%) Query: 66 TVYF--GMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEI 123 +VYF G+ VV G + V A++ + E FS R +++ G+ + Sbjct: 30 SVYFDEGLGVPVVLRGADVV--AVLRDSETFSTR----TYDTGIMKGALVTLGGEAHTRM 83 Query: 124 RRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVF 183 RR + + + R E V A +VE L + + + + + S +F Sbjct: 84 RRL-FNAVLSPRVISRYEEATVTPVARRVVERLVRKER--AELFDDFAISMPMGVTSALF 140 Query: 184 Q---KRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALT 240 +R D +++ +++ P + A Sbjct: 141 GLPEERIAENDALIRKMIR--------------------SVVMPQDPVVVAEGRSAHAAM 180 Query: 241 RSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTE 300 + +RE + A +P D + + + + +E G V L + E Sbjct: 181 EAQLREIAEREVA-----HPSDTLLGEIARAIVAEGLGG----VEACEGVVLTLILGSYE 231 Query: 301 TTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSD 360 TTS L L+ LL HP+ +++++ + E R+ Sbjct: 232 TTSWMLANLLVALLAHPDAMNQLRQQPS------------------LLPQAIEESTRWCS 273 Query: 361 LVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFK 420 G+ V + + GT + L + +D++ +P P FD Sbjct: 274 SA-AGIVRFVEREATIGGETLAAGTILYLSLIARHYDEEIYPRPETFDIHR--------- 323 Query: 421 KSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKG 475 + + F G C G LARME + ++ +L+ F D + +G Sbjct: 324 RPVGMLNFGGGLHYCVGAPLARMEARVGVSLLLERFPALRADPTVQPTFSTAPRG 378 >3WEC-A nrPDB Length = 419 Score = 137 bits (344), Expect = 1e-32, Method: Composition-based stats. Identities = 61/408 (14%), Positives = 114/408 (27%), Gaps = 64/408 (15%) Query: 77 FHGYEAVKEALIDNGEEFSGRGNSPISQRITKG--LGIISSNGKRWKEIRRFSLTTLRNF 134 G + D+ G P G + ++ +R Sbjct: 63 LFGKDFANSTFFDHLTSMMGEDMPPFLGLGIDGDARPFMLTDPPEHTRLRGLVSDAFTRS 122 Query: 135 GMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNF 194 S++D V A V L + + P V+ S++ KD+ Sbjct: 123 T--TTSMDDIVLSAASSAVRHLEHCTDAVSEVAEPF---PVEVLSSILG---IPDKDRGR 174 Query: 195 LTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQAS 254 + +N + ++ + + Y R + Sbjct: 175 FSEWSNLVAGVLDINFAIPKEV-------------ADRRSAAIEESIDYFRTL------A 215 Query: 255 LDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLL 314 N P L++ E + + +++ + T + VAG ETTS T+ L+ Sbjct: 216 TSGNAPE-----GLVRRLSEVSHGGDQLSVDEIAATCLLITVAGQETTSNTIGNMLITFS 270 Query: 315 KHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDT 374 +H + +V+ + + V E+ R+ D Sbjct: 271 RHADQFEQVRANPQ------------------FIENAVAEVLRFEPPAHEA-GRIALEDC 311 Query: 375 KFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRI 434 + I KG +M LL S + + F + + G Sbjct: 312 EVSGANITKGDAVMVLLASGNR--EAVERGDTFSVTR---------PDVSSLSYGRGIHH 360 Query: 435 CAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPS 482 C G LA L FL + Q + V + N +G +L + Sbjct: 361 CLGSALANSMLQHFLRELSQRYRSIEVAEPINYKPGMGLRGPETLSVA 408 >6BLD-A nrPDB Length = 419 Score = 136 bits (343), Expect = 2e-32, Method: Composition-based stats. Identities = 64/381 (16%), Positives = 116/381 (30%), Gaps = 54/381 (14%) Query: 103 SQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKAS 162 ++ + ++ + R ++R+ + R IED ++ A +V+ELR Sbjct: 93 AELLEASQSFLAMDPPRHTKLRKLVSAAFTPRQV--RRIEDSIKINAKGIVDELRMAGGG 150 Query: 163 PCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLL 222 P + +V D+ + + Sbjct: 151 VDFVEHCAKELPIRTLSDMVG---IPEADRERVA-----------------HAADALVSW 190 Query: 223 IDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEF 282 D + L + + Y+ + V A+ + P D + L+ E + D Sbjct: 191 ADPRYLNGREPLAVLFENQMYLHQ-VAASLAAERRDRPGDDLFSALVNAEVDGD----RL 245 Query: 283 NIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDR 342 ++ L VAG +TT T+ +GL L P A + + D IG Sbjct: 246 ADADVAAFFVLLAVAGNDTTRQTISHGLKALTDFPSQKAWLLADFDTRIGT--------- 296 Query: 343 SHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFP 402 V E+ R++ V D + LI G ++ S D+ F Sbjct: 297 --------AVEELVRWATPV-MTFRRTAAADFELGGQLIRAGEKVVMFYASGNWDEDAFC 347 Query: 403 NPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVD 462 +P D + + F C G LAR +L +L Sbjct: 348 HPERLDLSRSPNPHVGFGGGGVH--------FCLGAHLARAQLRAIFGELLVQLPDIQAG 399 Query: 463 DLKNLNTTAVTKGIVSLPPSY 483 D + I S+P ++ Sbjct: 400 DPVYV-PGNFVHAIRSMPCTF 419 >2IJ7-A nrPDB Length = 396 Score = 134 bits (336), Expect = 1e-31, Method: Composition-based stats. Identities = 59/362 (16%), Positives = 115/362 (31%), Gaps = 63/362 (17%) Query: 126 FSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVI-CSVVFQ 184 ++ +E +++ A+ L++ L +P D + C V+ Sbjct: 94 LRKAVMKAITPKAPGLEQFLRDTANSLLDNLITE-GAPADLRNDFADPLATALHCKVLGI 152 Query: 185 KRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYI 244 + D + FR L+ ++ + P N Y+ Sbjct: 153 PQEDGP------------KLFRSLSIAFMSSADPIPA-----------AKINWDRDIEYM 189 Query: 245 REKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTST 304 ++ + + L ++ KD S + E F AG +T + Sbjct: 190 AGILENPNITTG-------LMGELSRLR--KDPAYSHVSDELFATIGVTFFGAGVISTGS 240 Query: 305 TLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPT 364 L L+ L++ P++ + E+ + + A V E+ R + Sbjct: 241 FLTTALISLIQRPQLRNLLHEKPELI------------------PAGVEELLRINLSFAD 282 Query: 365 GVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDY 424 G+P T D + + L+ KG ++ LL D + FPNP + Sbjct: 283 GLPRLATADIQVGDVLVRKGELVLVLLEGANFDPEHFPNPGSIELDR--------PNPTS 334 Query: 425 FMPFSAGKRICAGEGLARMELFLFLTTILQNF---NLKSVDDLKNLNTTAVTKGIVSLPP 481 + F G+ C G L R + + +L+ +L D T + LP Sbjct: 335 HLAFGRGQHFCPGSALGRRHAQIGIEALLKKMPGVDLAVPIDQLVWRTRFQRRIPERLPV 394 Query: 482 SY 483 + Sbjct: 395 LW 396 >6DCD-A nrPDB Length = 424 Score = 133 bits (335), Expect = 2e-31, Method: Composition-based stats. Identities = 77/472 (16%), Positives = 133/472 (28%), Gaps = 96/472 (20%) Query: 48 KDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSG-------RGNS 100 D F PV + +V GYE A+ + + FS Sbjct: 17 PDPHPYFDYLRSQ-SPV--LRLPQYGVVAVTGYEEA-TAVYKDTDSFSNCVALGGPFPPL 72 Query: 101 PISQRITKGLG--------------IISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQ 146 P + +++ + R L + + E+ + Sbjct: 73 PFAPNGDDVNAQIDAHREQFPMYEHMVTMDPPEHSRARSILSRLLTPSRL--KQNEEFMW 130 Query: 147 EEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFR 206 A ++E + A VI ++ D KD + R Sbjct: 131 RLADRQLDEFLGAGECEFISEYAKPFATL-VIADLLGVPEDDRKDFRVVLGADRMGRVGA 189 Query: 207 ILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDC 266 + + N L D F +++ + PR+ + Sbjct: 190 LDHESVG--VNPLQWLDDKF------------------SAYIEDRRR-----QPRNDVLT 224 Query: 267 FLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEE 326 L + + +V + LF AG ETT+ L + +L P++ +++E Sbjct: 225 ALATATYPDGSTPEVID---VVRSATFLFAAGQETTAKLLTAAMRVLGDRPDIQRRLREN 281 Query: 327 IDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTT 386 RS +P + E R V + T I GT Sbjct: 282 ---------------RSLIP---NFIEESLRMDSPVKSD-SRLARKRTTVGGLDIAAGTV 322 Query: 387 IMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELF 446 +M L + D + F +P+ F M F+ G C G LAR+E Sbjct: 323 VMVLPGAANRDPRRFEDPHEFRLDR--------PNVREHMAFARGVHSCPGGPLARVEGR 374 Query: 447 LFLTTILQNF-------NLKSVDDLKNLNTTA--VTKGIVSLPPSYQICFIP 489 + L IL + D + + +G+ L I F P Sbjct: 375 VSLERILDRMLDIAINEDRHGPADDRRYTYEPTYILRGLTEL----HITFTP 422 >1WIY-A nrPDB Length = 389 Score = 131 bits (330), Expect = 6e-31, Method: Composition-based stats. Identities = 73/432 (16%), Positives = 132/432 (30%), Gaps = 73/432 (16%) Query: 36 LPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFS 95 P + ++ +D + + + +F + P+ + E V+ AL+ G + Sbjct: 10 WPYLKDL----QQDPLAVLLEWGRAHPRLF-LPLPRFPLALIFDPEGVEGALLAEGTTKA 64 Query: 96 GRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEE 155 +S+ G G+++ GK WKE R+ + R + ++EEA E Sbjct: 65 TFQYRALSRLT--GRGLLTDWGKSWKEARKALKDPFLPKSV--RGYREAMEEEAWAFFGE 120 Query: 156 LRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQV 215 R + D + ++ +F K Sbjct: 121 WRGEER---DLDHEMLALSLRLLGRALFGK------------------------------ 147 Query: 216 CNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEK 275 P LK + + R + + + +D + Sbjct: 148 --------PLSPSLAEHALKALDRIMAQTRSPLALLDLAAEARFRKDRGALYREAEALIV 199 Query: 276 DNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHR 335 S E + L VAG ET ++ L + LLL P+ +V E + + + Sbjct: 200 HPPLSHLPRERALSEAVTLLVAGHETVASALTWSFLLLSHRPDWQKRVAESEEAALAAFQ 259 Query: 336 SPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVL 395 E R + +P+GTT++ Sbjct: 260 ------------------EALRLYPPAWILTRR-LERPLLLGEDRLPQGTTLVLSPYVTQ 300 Query: 396 HDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQN 455 FP F P FL + G S + PF G+R+C G A +E + L + Sbjct: 301 R--LYFPEGEAFQPERFLAERGT--PSGRYFPFGLGQRLCLGRDFALLEGPIVLRAFFRR 356 Query: 456 FNLKSVDDLKNL 467 F L + + L Sbjct: 357 FRLDPLPFPRVL 368 >2WIY-A nrPDB Length = 394 Score = 131 bits (329), Expect = 8e-31, Method: Composition-based stats. Identities = 65/442 (14%), Positives = 129/442 (29%), Gaps = 74/442 (16%) Query: 46 DVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAV----KEALIDNGEEFSGRGNSP 101 + + + + PV + G + Y V K ++ ++ G Sbjct: 18 FRNNPYPWYRRLQQDH-PVHKLEDG---TYLVSRYADVSHFAKLPIMSVEPGWADAGPWA 73 Query: 102 ISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRK--T 159 ++ G S+ +RR T + F + ++ V+ LV +L Sbjct: 74 VASDTALG-----SDPPHHTVLRR---QTNKWFT--PKLVDGWVR-TTRELVGDLLDGVE 122 Query: 160 KASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNF 219 + L P +V + V Q D D + F Sbjct: 123 AGQVIEARRDLAVVPTHVTMARVLQLPEDDADAVMEAM---------------------F 161 Query: 220 PLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQK 279 ++ + + A+ Y+ +V E VN D L Sbjct: 162 EAMLMQSAEPADGDVDRAAVAFGYLSARVAEMLEDKRVNPGDGLADSLLDAARA------ 215 Query: 280 SEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCM 339 E + T+ + G + G+ L + PEV + + Sbjct: 216 GEITESEAIATILVFYAVGHMAIGYLIASGIELFARRPEVFTAFRNDESARA-------- 267 Query: 340 QDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDK 399 A+++E+ R T D + LI G+ I ++ + D + Sbjct: 268 ----------AIINEMVRMDPP-QLSFLRFPTEDVEIGGVLIEAGSPIRFMIGAANRDPE 316 Query: 400 EFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLK 459 F +P++FD + N + F G CAG+ ++R E + + + Sbjct: 317 VFDDPDVFDHTRPPAASRN-------LSFGLGPHSCAGQIISRAEATTVFAVLAERYERI 369 Query: 460 SVDDLKNLNTTAVTKGIVSLPP 481 + + + + LP Sbjct: 370 ELAEEPTVAHNDFARRYRKLPI 391 >5D3U-A nrPDB Length = 427 Score = 130 bits (326), Expect = 1e-30, Method: Composition-based stats. Identities = 72/394 (18%), Positives = 116/394 (29%), Gaps = 56/394 (14%) Query: 91 GEEFSGRGNSP--ISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEE 148 +F G+ P I R TK + ++ ++ +RR + + +Q+ Sbjct: 86 AAKFPGQPLPPDNIFHRWTKNV-VMYTDPPLHDALRRSVRAGFTR--AAHQHYDQVLQKV 142 Query: 149 AHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRIL 208 AH LV + + P S V +D FL + R N Sbjct: 143 AHDLVASIPAGATEIDAVPALAAELPVR---SAVHAFGVPEEDLGFL--IPRVNTIMTYF 197 Query: 209 NSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFL 268 + P Q P T +L+ + +Y E ++ + + D + L Sbjct: 198 SGPKDQ------------PVTQEIILEKLTDLHTYASELLQGMRGKVLP----DTVIARL 241 Query: 269 IKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEID 328 + E + L LF TT +L G L ++P + + Sbjct: 242 AAAQDGLTETTPEQTVHQLALVFIALFAP---TTPGSLSSGTLAFARNPRQVERFLADQA 298 Query: 329 HVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIM 388 V D +E+ RY+ D + I G T+ Sbjct: 299 CV------------------DNTANEVLRYNASNQFTW-RVAAKDVEMGGVRIEAGQTLA 339 Query: 389 ALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLF 448 L S D F PN FD S + F G C L ++L F Sbjct: 340 LFLGSANRDANMFERPNDFDLDR--------PNSARHLSFGQGVHACLAAQLISLQLKWF 391 Query: 449 LTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPS 482 +L F N + + SLP S Sbjct: 392 YVALLNRFPGIRTAGEPIWNENLEFRSLRSLPLS 425 >6G71-A nrPDB Length = 405 Score = 128 bits (321), Expect = 7e-30, Method: Composition-based stats. Identities = 60/380 (15%), Positives = 114/380 (30%), Gaps = 61/380 (16%) Query: 108 KGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEE-LRKTKASPCDP 166 G ++ + + RR +L+ G K+ + + E A ++ + S Sbjct: 76 MGHSMLRKDDPDHQVERRAWQPSLKP-GTVKKVWKQKFAENADRYLDAYIDAGSGSDFMQ 134 Query: 167 TFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCF 226 F N+ + F+ + Q W Q + Sbjct: 135 GFAAPFVAENLRALIGFENASEADLQR------------------WSQTLIDGAGNYPDD 176 Query: 227 PGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIEN 286 P K ++ + + E ++ H P D + +L++ + +E+ Sbjct: 177 PDVWAKAKQSSDEIDAALEEMIQWH-----SGRPGDSLLSYLLRSADY------QMPLES 225 Query: 287 LVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMP 346 + + G L L LL + V + Sbjct: 226 IRSNIKMTIGGGLNEPRDVLGVSTLALLSSSKQLELVLRDPK------------------ 267 Query: 347 YTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNI 406 AV E R+ + VP DT+ Y IP+G + + S D + +P+ Sbjct: 268 LWGAVFEESIRWVAPI-GMVPRQTVVDTELDGYFIPRGAKLGLCILSANRDRSVWSDPDR 326 Query: 407 FDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARME-LFLFLTTILQNFNLKSVDDLK 465 FD S+ + F G +C G AR + + L + +D + Sbjct: 327 FDIER---------GSEAHLAFGKGVHVCLGAWAARSQVADVGLPALFSRLKGLRLDPNQ 377 Query: 466 NLNTTA-VTKGIVSLPPSYQ 484 V +G +SLP + Sbjct: 378 EATHGGWVFRGPLSLPLVWD 397 >3BUJ-A nrPDB Length = 397 Score = 124 bits (312), Expect = 6e-29, Method: Composition-based stats. Identities = 63/427 (14%), Positives = 127/427 (29%), Gaps = 69/427 (16%) Query: 67 VYFGMNPIVVFHGYEAVKEALIDNGEEFSG--R--GNSPISQRITKGLG--IISSNGKRW 120 V+ G + + + V+ L D +G R + + + +G I+ + Sbjct: 28 VHRGAHRVWYVSRFADVRAVLGDERFARTGIRRFWTDLVGPGLLAEIVGDIILFQDEPDH 87 Query: 121 KEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICS 180 +R + R +E + L+ L +V+ Sbjct: 88 GRLRGVVGPAFSPSAL--RRLEPVIAGTVDDLL-------------RPALARGAMDVVDE 132 Query: 181 VVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFP-GTHNKVLKNVAL 239 + + ++ + + W V + G + ++ Sbjct: 133 LAYPL-----------ALRAVLGLLGLPAADWGAVGRWSRDVGRTLDRGASAEDMRRGHA 181 Query: 240 TRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGT 299 + + V+ A D + L + + + +V TV G Sbjct: 182 AIAEFADYVERALARRRREGGEDLLALMLDA------HDRGLMSRNEIVSTVVTFIFTGH 235 Query: 300 ETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYS 359 ET ++ + +L LL HP+ ++ D V E RY Sbjct: 236 ETVASQVGNAVLSLLAHPDQLDLLRRRPD------------------LLAQAVEECLRYD 277 Query: 360 DLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNF 419 V + + D + R + + ++ L + D + + P+ FD Sbjct: 278 PSVQSNT-RQLDVDVELRGRRLRRDDVVVVLAGAANRDPRRYDRPDDFDIER-------- 328 Query: 420 KKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQN--FNLKSVDDLKNLNTTAVTKGIV 477 M F AG R C G LAR +L + + + L D + +G+ Sbjct: 329 -DPVPSMSFGAGMRYCLGSYLARTQLRAAVAALARLPGLRLGCASDALAYQPRTMFRGLA 387 Query: 478 SLPPSYQ 484 SLP ++ Sbjct: 388 SLPIAFT 394 >3OFT-A nrPDB Length = 396 Score = 119 bits (298), Expect = 3e-27, Method: Composition-based stats. Identities = 67/372 (18%), Positives = 105/372 (28%), Gaps = 67/372 (18%) Query: 116 NGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILG-CAP 174 +G K R + L + ++E +VQ A L+E LR CD P Sbjct: 90 DGAEHKAFRTPVMKGLAS--RFVVALEPKVQAVARKLMESLRP--RGSCDFVSDFAEILP 145 Query: 175 CNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVL 234 N+ FLTL+ E+ L +Q+ P V Sbjct: 146 LNI----------------FLTLIDVPLEDRPRLRQLGVQLTR---------PDGSMTVE 180 Query: 235 KNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADL 294 + Y+ +++ A P D + ++ + ++ +L Sbjct: 181 QLKQAADDYLWPFIEKRMA-----QPGDDLFSRILSEPVGG----RPWTVDEARRMCRNL 231 Query: 295 FVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHE 354 G +T + + L L +HPE ++E D + A E Sbjct: 232 LFGGLDTVAAMIGMVALHLARHPEDQRLLRERPDLI------------------PAAADE 273 Query: 355 IQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLD 414 + R V V D I KG + D F P L Sbjct: 274 LMRRYPTV--AVSRNAVADVDADGVTIRKGDLVYLPSVLHNLDPASFEAPEEVRFDRGLA 331 Query: 415 KNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNF-NLKSVDDLKNLNTTAVT 473 G C G GLARME+ +FL L D Sbjct: 332 -------PIRHTTMGVGAHRCVGAGLARMEVIVFLREWLGGMPEFALAPDKAVTMKGGNV 384 Query: 474 KGIVSLPPSYQI 485 +LP ++ Sbjct: 385 GACTALPLVWRA 396 >3B98-A nrPDB Length = 475 Score = 117 bits (294), Expect = 9e-27, Method: Composition-based stats. Identities = 92/499 (18%), Positives = 166/499 (33%), Gaps = 66/499 (13%) Query: 19 LWRQSC--------RRRKLPPGPTP-LPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYF 69 + +++ RRR PP +P +G+ L+ KD K T + +G +FTV Sbjct: 1 MAKKTSSVLYGRRTRRRNEPPLDKGMIPWLGHALEFG-KDAAKFLTRMKEKHGDIFTVRA 59 Query: 70 GMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLT 129 I V L D + +RI I+ S+ ++ R Sbjct: 60 AGLYITVLLDSNCYDAVLSDVASLDQTSYAQVLMKRIFNM--ILPSHNPESEKKRAEMHF 117 Query: 130 TLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDY 189 + S++ LR +P + + + ++ + F Sbjct: 118 QGASLTQLSNSMQ-----------NNLRLLM-TPSEMGLKTSEWKKDGLFNLCYSLLFK- 164 Query: 190 KDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNK-VLKNVALTRSYIREKV 248 +LT+ N N ++ Q+ F P V K S REK+ Sbjct: 165 --TGYLTVFGAENNN----SAALTQIYEEFRRFDKLLPKLARTTVNKEEKQIASAAREKL 218 Query: 249 KEHQA-SLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFV----AGTETTS 303 + S PR+ +L ++ ++ + ++ + L+V AG Sbjct: 219 WKWLTPSGLDRKPRE--QSWLGSYVKQLQDEGIDAEMQR-RAMLLQLWVTQGNAGP---- 271 Query: 304 TTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVP 363 + + LL HPE V+EEI G + + + P D+V+ E R + Sbjct: 272 -AAFWVMGYLLTHPEALRAVREEIQ---GGKHLRLEERQKNTPVFDSVLWETLRLT--AA 325 Query: 364 TGVPHAVTTDTKF-----RNYLIPKGTTIMALL-TSVLHDDKEFPNPNIFDPGHFLDKNG 417 + VT D K + Y + +G + S D + P +F FL+ + Sbjct: 326 ALITRDVTQDKKICLSNGQEYHLRRGDRLCVFPFISPQMDPQIHQQPEMFQFDRFLNADR 385 Query: 418 NFKK---------SDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLN 468 KK +P+ +C G A + + TIL F+++ D + Sbjct: 386 TEKKDFFKNGARVKYPSVPWGTEDNLCPGRHFAVHAIKELVFTILTRFDVELCDKNATVP 445 Query: 469 T-TAVTKGIVSLPPSYQIC 486 G L P+ + Sbjct: 446 LVDPSRYGFGILQPAGDLE 464 >5OMS-A nrPDB Length = 409 Score = 117 bits (294), Expect = 1e-26, Method: Composition-based stats. Identities = 58/388 (14%), Positives = 114/388 (29%), Gaps = 52/388 (13%) Query: 101 PISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTK 160 P R II NG ++R L+ R I+D V+ A +E Sbjct: 71 PAGGRTFGHPAIIGVNGDIHADLRSMVEPALQP-AEVDRWIDDLVRPIARRYLERFEN-- 127 Query: 161 ASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFP 220 D L C + ++ + L + F + R + + F Sbjct: 128 ----DGHAELVAQYCEPVSVRSLGDLLGLQEVDSDKLREWFAKLNRSFTNAAVDENGEFA 183 Query: 221 LLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKS 280 G K A R+ + + + D D + + Sbjct: 184 NPEGFAEGDQAK-----AEIRAVVDPLIDKWIEHPD--------DSAISHWLHDGMPPGQ 230 Query: 281 EFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQ 340 + E + T+ + + + L+ L PE +V ++ Sbjct: 231 TRDREYIYPTIYVYLLGAMQEPGHGMASTLVGLFSRPEQLEEVVDDP------------- 277 Query: 341 DRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKE 400 + E R++ + + T +P GT +M S HD + Sbjct: 278 -----TLIPRAIAEGLRWTSPIWSATARISTKPVTIAGVDLPAGTPVMLSYGSANHDTGK 332 Query: 401 FPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQ---NFN 457 + P+ +D + + F AG CAG A + + L + + N Sbjct: 333 YEAPSQYD---------LHRPPLPHLAFGAGNHACAGIYFANHVMRIALEELFEAIPNLE 383 Query: 458 LKSVDDLKNLNTTAVTKGIVSLPPSYQI 485 + + ++ +G SL ++++ Sbjct: 384 RDTREGVEFWGWG--FRGPTSLHVTWEV 409 >4FB2-A nrPDB Length = 398 Score = 115 bits (289), Expect = 3e-26, Method: Composition-based stats. Identities = 63/412 (15%), Positives = 122/412 (29%), Gaps = 71/412 (17%) Query: 76 VFHGYEAVKEALIDNGEEFSGRG-NSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNF 134 V GY+ + +A+I N + FS +G P + L + + K+ R+ Sbjct: 48 VVAGYKEI-QAVIQNTKAFSNKGVTFPRYETGEFELMMAGQDDPVHKKYRQLVAKPFSP- 105 Query: 135 GMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNF 194 E E+LR++ D LG + + Sbjct: 106 ------------EATDLFTEQLRQSTNDLIDARIELG----------------EGDAATW 137 Query: 195 LTLMKRFNENFRILNSPWIQVCNNFPL-LIDCFPGTHNKVLKNVALTRSYIREKVKEHQA 253 L +L P + + A ++ R + E + Sbjct: 138 LANEIPARLTAILLGLPPEDGDTYRRWVWAITHVENPEEGAEIFAELVAHARTLIAERR- 196 Query: 254 SLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLL 313 NP + I +I + + ++ + ++L+G L + G + T+ L L Sbjct: 197 ----TNPGNDIMSRVIMSKIDGES----LSEDDLIGFFTILLLGGIDNTARFLSSVFWRL 248 Query: 314 LKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTD 373 E+ ++ + + V E+ R+ G VT + Sbjct: 249 AWDIELRRRLIAHPELI------------------PNAVDELLRFYGPAMVG--RLVTQE 288 Query: 374 TKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKR 433 + + G T M D F +P+ + + G Sbjct: 289 VTVGDITMKPGQTAMLWFPIASRDRSAFDSPDNIVIER---------TPNRHLSLGHGIH 339 Query: 434 ICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLN-TTAVTKGIVSLPPSYQ 484 C G L R+E + +T L+ S+D K G++ +P + Sbjct: 340 RCLGAHLIRVEARVAITEFLKRIPEFSLDPNKECEWLMGQVAGMLHVPIIFP 391 >2QBO-A nrPDB Length = 421 Score = 114 bits (285), Expect = 1e-25, Method: Composition-based stats. Identities = 62/367 (16%), Positives = 108/367 (29%), Gaps = 70/367 (19%) Query: 122 EIRRFSLTTLRNFGMGK-RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICS 180 E R+F + GM +E+R+QE A L+E LR Sbjct: 108 EQRQFRALANQVVGMPVVDKLENRIQELACSLIESLRPQ--------------------- 146 Query: 181 VVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHN--KVLKNVA 238 Q F + F +L + + L D + Sbjct: 147 --GQCNFTEDYAEPFPI-----RIFMLLAGLPEEDIPHLKYLTDQMTRPDGSMTFAEAKE 199 Query: 239 LTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAG 298 Y+ +++ + + I + + L V G Sbjct: 200 ALYDYLIPIIEQRRQKPGTDA---------ISIVANGQVNGRPITSDEAKRMCGLLLVVG 250 Query: 299 TETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRY 358 +T L + + L K PE ++ E + + A E+ R Sbjct: 251 LDTVVNFLSFSMEFLAKSPEHRQELIERPERI------------------PAACEELLRR 292 Query: 359 SDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGN 418 LV G +T+D +F + KG I+ D++E P D Sbjct: 293 FSLVADG--RILTSDYEFHGVQLKKGDQILLPQMLSGLDERENACPMHVDFSR------- 343 Query: 419 FKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNT-TAVTKGIV 477 + F G +C G+ LAR E+ + L L S+ + + + G+ Sbjct: 344 --QKVSHTTFGHGSHLCLGQHLARREIIVTLKEWLTRIPDFSIAPGAQIQHKSGIVSGVQ 401 Query: 478 SLPPSYQ 484 +LP + Sbjct: 402 ALPLVWD 408 >5KYO-A nrPDB Length = 430 Score = 109 bits (273), Expect = 3e-24, Method: Composition-based stats. Identities = 72/415 (17%), Positives = 126/415 (30%), Gaps = 73/415 (17%) Query: 64 VFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGII--SSNGKRWK 121 ++T + G + + + + E ++ + E FS + + +I S + + Sbjct: 75 MWTPHNGGHWVALRSD---LAETVMSDFERFSNHTVLVPKETAGEAYRLIPLSLDPPEHR 131 Query: 122 EIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSV 181 R L + R IE V + A L+E R F Sbjct: 132 PFRSLLNENLGPKPL--RPIEQVVTDLAVSLIEGFRPKGRCNFTHEFAEQLPVR------ 183 Query: 182 VFQKRFDYKDQNFLTLMKRFNENFRILNS-PWIQVCNNFPLLIDCFPGTHNKVLKNVALT 240 +F + D ++ L ++ R S P V F Sbjct: 184 IFMRIVDLPVEDLPKLKHLADQYTRPDGSIPLDDVTKQF--------------------- 222 Query: 241 RSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTE 300 R Y+R ++ + P + + +I E ++ EN+ + V G + Sbjct: 223 REYLRPVIEARRI-----KPGEDMISRMINGEV-GGRPLTDIEAENI---CIQVLVGGLD 273 Query: 301 TTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSD 360 T L + L K + + + + D + E R Sbjct: 274 TVVNMLGFTFSHLAKDHALRRAIAADPSLI------------------DDALLEFFRRFP 315 Query: 361 LVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFK 420 +V + V D +F L+ G +MA V DD +P F G Sbjct: 316 VVSSA--REVLRDQEFEGVLLKAGDMVMAPTVVVAMDDARNEDPLEFRLGR--------- 364 Query: 421 KSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKG 475 K+ F G C G LARME+ + L ++D L + G Sbjct: 365 KARQHSTFGKGSHTCPGAHLARMEMKVVLREWFARIPEFRIEDDAPLRYSNGIVG 419 >6FYJ-A nrPDB Length = 421 Score = 109 bits (271), Expect = 3e-24, Method: Composition-based stats. Identities = 68/438 (15%), Positives = 142/438 (32%), Gaps = 64/438 (14%) Query: 45 IDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSP--I 102 + + +F + G EA E D E+F + +P + Sbjct: 21 LMEEGYMYILNRRHSFNSDIFETRLLGKKAICMGGKEAA-EIFYDT-EKFKRKDAAPNRV 78 Query: 103 SQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKAS 162 Q + G+ + +G+ K + ++ + + K + D +++ V++ + Sbjct: 79 VQTLFGKNGVQALDGQTHKHRKEMFMSIMSPDELEK--LTDITKKQWEIAVDKWEQMD-- 134 Query: 163 PCDPTFILGCAPCNVICSV-VFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPL 221 IL ++C ++ L K F + Sbjct: 135 ----KVILYEEAKEIMCRTACQWAGVPVQENEVKRLTKNLGAMFESAAA----------- 179 Query: 222 LIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSE 281 G + + ++ E++ + VN P + L K +D + + Sbjct: 180 -----VGLKHWLGRHARNYEEIWIEELIDRVRDGKVNPPEN---TTLHKFSWYRDLEGNL 231 Query: 282 FNIENLVGTVADLF---VAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPC 338 + E V ++ VA + + + L L +PE K++ Sbjct: 232 LDTETAAVEVINILRPIVA----IAIFINFIALALHHYPEEKEKLKS------------- 274 Query: 339 MQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDD 398 Y+ V E++R+ P V V D ++ Y +GT + L HD Sbjct: 275 ----GDKKYSQMFVQEVRRFYPFFPFVVA-LVKKDFTWKGYKFEEGTLTLLDLYGTNHDP 329 Query: 399 KEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGK----RICAGEGLARMELFLFLTTILQ 454 + + NP++F P F G+ F+P G CAGE + + + L + Sbjct: 330 EIWKNPDVFSPDRFAKWEGS---PFSFIPQGGGDYFMGHRCAGEWVTIEVMKVSLDYLTN 386 Query: 455 NFNLKSVDDLKNLNTTAV 472 + + D + + ++ Sbjct: 387 RMDYEVPDQDLSFSMASM 404 >2IAG-A nrPDB Length = 482 Score = 108 bits (269), Expect = 7e-24, Method: Composition-based stats. Identities = 86/506 (16%), Positives = 165/506 (32%), Gaps = 70/506 (13%) Query: 22 QSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVF---H 78 ++ R + P +P +G L KD T + +G +FT+ G + V H Sbjct: 1 RTRRPGEPPLDLGSIPWLGYALDFG-KDAASFLTRMKEKHGDIFTILVGGRYVTVLLDPH 59 Query: 79 GYEAV----KEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNF 134 Y+AV + L + Q + K R T + Sbjct: 60 SYDAVVWEPRTRLDFHAYAIFLMERIFDVQLPHYSPSDEKARMKLTLLHRELQALTEAMY 119 Query: 135 GMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNF 194 + E E D S F R Y Sbjct: 120 TNLHAVLLGDATEAGSGWHEM------GLLDF-------------SYSFLLRAGYLTLYG 160 Query: 195 LTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLK-----NVALTRSYIREKVK 249 + + R +E+ V + F L P L ++ +S + + + Sbjct: 161 IEALPRTHESQAQDRVHSADVFHTFRQLDRLLPKLARGSLSVGDKDHMCSVKSRLWKLLS 220 Query: 250 EHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYG 309 + + + +++ +L+ +E+ + E + A + Sbjct: 221 PARLARRA-HRSKWLESYLLHLEEMG------VSEEMQARALVLQLWATQGNMGPAAFWL 273 Query: 310 LLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQD-------RSHMPYTDAVVHEIQRYSDLV 362 LL LLK+PE A V+ E++ ++ + P Q P D+V+ E R + Sbjct: 274 LLFLLKNPEALAAVRGELESILWQAEQPVSQTTTLPQKVLDSTPVLDSVLSESLRLT--A 331 Query: 363 PTGVPHAVTTDTKF-----RNYLIPKGTTIMALL-TSVLHDDKEFPNPNIFDPGHFLDKN 416 + V D R + + +G ++ S D + + +P +F FL+ + Sbjct: 332 APFITREVVVDLAMPMADGREFNLRRGDRLLLFPFLSPQRDPEIYTDPEVFKYNRFLNPD 391 Query: 417 GNFKK---------SDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSV---DDL 464 G+ KK +Y MP+ AG C G A + F+ +L + +L+ + ++ Sbjct: 392 GSEKKDFYKDGKRLKNYNMPWGAGHNHCLGRSYAVNSIKQFVFLVLVHLDLELINADVEI 451 Query: 465 KNLNTTAVTKGI----VSLPPSYQIC 486 + + G+ +P Y+I Sbjct: 452 PEFDLSRYGFGLMQPEHDVPVRYRIR 477 >3NV6-A nrPDB Length = 452 Score = 103 bits (257), Expect = 2e-22, Method: Composition-based stats. Identities = 58/375 (15%), Positives = 120/375 (32%), Gaps = 65/375 (17%) Query: 116 NGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPC 175 + R+ L + R +ED+V+E A L++ Sbjct: 140 DPPEHTPYRKALDKGLNLAKI--RKVEDKVREVASSLIDSFAARGE-------------- 183 Query: 176 NVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLK 235 C + + F+ L E+ +L+ Q+ + + Sbjct: 184 ---CDFAAEYAELFPVHVFMALADLPLEDIPVLSEYARQMT---RPEGNTPEEMATDLEA 237 Query: 236 NVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLF 295 +Y+ ++ V D + ++ E + + G ++ L Sbjct: 238 GNNGFYAYVDPIIRAR-----VGGDGDDLITLMVNSEINGE----RIAHDKAQGLISLLL 288 Query: 296 VAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEI 355 + G +T L + ++ L +HPE+ A+++ + ++ E+ Sbjct: 289 LGGLDTVVNFLSFFMIHLARHPELVAELRSDPLKLMRGA------------------EEM 330 Query: 356 QRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDK 415 R +V V D +++ + +G I+ DD P P D Sbjct: 331 FRRFPVVSEA--RMVAKDQEYKGVFLKRGDMILLPTALHGLDDAANPEPWKLDFSR---- 384 Query: 416 NGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQN---FNLKSVDDLKNLNTTAV 472 +S F G CAG LARME+ + L L+ F+ K + + + + Sbjct: 385 -----RSISHSTFGGGPHRCAGMHLARMEVIVTLEEWLKRIPEFSFK--EGETPIYHSGI 437 Query: 473 TKGIVSLPPSYQICF 487 + ++P + I Sbjct: 438 VAAVENVPLVWPIAR 452 >5YHJ-A nrPDB Length = 413 Score = 101 bits (252), Expect = 6e-22, Method: Composition-based stats. Identities = 73/425 (17%), Positives = 141/425 (33%), Gaps = 64/425 (15%) Query: 64 VFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSP--ISQRITKGLGIISSNGKRWK 121 +F ++ G EA E D +F+ + +P + + + G+ + +G Sbjct: 36 IFESRLLGERVICLGGEEAA-EVFYD-ANKFTRQDAAPKRLLKTLFGEGGVQTLDGSEHT 93 Query: 122 EIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSV 181 R+ +L R + +E +E + I +C Sbjct: 94 -HRKQMFMSLMTKENIDRLLRLTYREWNQ--IERM----GEEIVLYDIAQEVLMKAVCEW 146 Query: 182 VFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTR 241 + M+ E+ L ++Q + ++ A Sbjct: 147 SGVPLAKEEVGKRTEEMRLLFESGTSLGPTYLQ----------------GRKARSSAEVW 190 Query: 242 SYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTET 301 IR+ VKE +++ + N + + ++ E E +V + T Sbjct: 191 --IRQMVKEVRSNRLLPN-----EHTALYEFSWHRDESGELLPEEVVAVEVLNILRPTVA 243 Query: 302 TSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDL 361 S + + +L L + P+V +V +R + T+ V E++R+ Sbjct: 244 ISVYVLFTVLALHQFPDVKEQV-----------------ERGEVSKTE-FVQEVRRFYPF 285 Query: 362 VPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKK 421 P V TD ++ Y P+GT + L HD + P+ FDP F D + Sbjct: 286 FPVAAAR-VKTDFEWDGYAFPEGTLTLLDLYGTNHDVSIWTEPDRFDPSRFKDWKES--- 341 Query: 422 SDYFMPFSAGK----RICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIV 477 F+P G CAGE + L +++ F + + + + + Sbjct: 342 PFNFIPQGGGDVDFGHRCAGEHVTIA----ILAQVIELFTKEYAYTVPPQDLSYSFVDMP 397 Query: 478 SLPPS 482 SLP S Sbjct: 398 SLPKS 402 >2ZQJ-A nrPDB Length = 417 Score = 100 bits (249), Expect = 1e-21, Method: Composition-based stats. Identities = 74/451 (16%), Positives = 138/451 (30%), Gaps = 62/451 (13%) Query: 39 IGNMLQIDVKDICKSFTNFSKVY-GPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGR 97 + N L + + N ++ Y +F + G EA K D + F + Sbjct: 11 LDNSLTLLKEG-YLFIKNRTERYNSDLFQARLLGKNFICMTGAEAAK-VFYDT-DRFQRQ 67 Query: 98 GNSPI-SQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEEL 156 P Q+ G+ I R+ +L KR + + + EE V Sbjct: 68 NALPKRVQKSLFGVNAIQGMDGSAHIHRKMLFLSLMTPPHQKR-LAELMTEEWKAAVTRW 126 Query: 157 RKTKASPCDPTFILGCAPCNVICSV-VFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQV 215 K D + A ++C V + K+ F + + + Sbjct: 127 EK-----ADEVVLFEEAK-EILCRVACYWAGVPLKETEVKERADDFIDMVDAFGAVGPR- 179 Query: 216 CNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEK 275 H K + +I +++ +A L + +++ Sbjct: 180 --------------HWKGRRARPRAEEWIEVMIEDARAGLLKTTSGTALHEMAFHTQEDG 225 Query: 276 DNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHR 335 S L+ + + S L + L L +HP+ ++ G R Sbjct: 226 SQLDSRMAAIELINVLRPIVA-----ISYFLVFSALALHEHPKYKEWLRS------GNSR 274 Query: 336 SPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVL 395 + V E++RY P V D + N KGT+++ L Sbjct: 275 E-----------REMFVQEVRRYYPFGPFLGA-LVKKDFVWNNCEFKKGTSVLLDLYGTN 322 Query: 396 HDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGK----RICAGEGLARMELFLFLTT 451 HD + + +P+ F P F ++ N +P G C GEG+ + L Sbjct: 323 HDPRLWDHPDEFRPERFAEREENL---FDMIPQGGGHAEKGHRCPGEGITIEVMKASLDF 379 Query: 452 ILQNFNLKSVDDLKNLNTTAVTKGIVSLPPS 482 ++ + + + + SLP S Sbjct: 380 LVHQIEYDVPEQSLHYSLAR----MPSLPES 406 >4C9K-A nrPDB Length = 421 Score = 97.1 bits (240), Expect = 2e-20, Method: Composition-based stats. Identities = 74/475 (15%), Positives = 147/475 (30%), Gaps = 73/475 (15%) Query: 19 LWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFH 78 + + R PP P +I + D+ + + F K T P F Sbjct: 5 TSTATQKHRVAPPPHVPGHLIREIDAYDLDGLEQGFHEAWKRVQQPDTPPLVWTP---FT 61 Query: 79 GYEAVKEA------LIDNGEEFSGRGNSPISQRITKGLGIISS--NGKRWKEIRRFSLTT 130 G + + + E FS R + + + ++ + + R+ Sbjct: 62 GGHWIATRGTLIDEIYRSPERFSSRVIW-VPREAGEAYDMVPTKLDPPEHTPYRKAIDKG 120 Query: 131 LRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYK 190 L + R +ED+++ A ++E F P V ++ + Sbjct: 121 LNLAEI--RKLEDQIRTIAVEIIEGFADRGHCEFGSEFS-TVFPVRVFLALAG---LPVE 174 Query: 191 DQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKE 250 D L L+ + T + +++ E V Sbjct: 175 DATKLGLLAN--------------------EMTRPSGNTPEEQGRSLEAANKGFFEYVAP 214 Query: 251 HQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGL 310 A+ + D I L + + +G V+ L + G +T L + + Sbjct: 215 IIAARRGGSGTDLITRIL-----NVEIDGKPMPDDRALGLVSLLLLGGLDTVVNFLGFMM 269 Query: 311 LLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAV 370 + L +HPE A+++ E V E+ R +V V Sbjct: 270 IYLSRHPETVAEMRREPLK------------------LQRGVEELFRRFAVVSDA--RYV 309 Query: 371 TTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSA 430 +D +F ++ +G I+ DD+ +P D + F+ Sbjct: 310 VSDMEFHGTMLKEGDLILLPTALHGLDDRHHDDPMTVDLSR---------RDVTHSTFAQ 360 Query: 431 GKRICAGEGLARMELFLFLTTILQNF-NLKSVDDLKNLNTTAVTKGIVSLPPSYQ 484 G CAG LAR+E+ + L L + D + + + + ++P ++ Sbjct: 361 GPHRCAGMHLARLEVTVMLQEWLARIPEFRLKDRAVPIYHSGIVAAVENIPLEWE 415 >5M0P-A nrPDB Length = 428 Score = 93.6 bits (231), Expect = 2e-19, Method: Composition-based stats. Identities = 58/439 (13%), Positives = 134/439 (30%), Gaps = 51/439 (11%) Query: 39 IGNMLQIDVKDICKSFTNFSKVYGPVFTVY-FGMNPIVVFHGYEAVKEALIDNGEEFSGR 97 + N L++ + + +++ VF G P VV G E + ++ + G Sbjct: 16 LDNTLKVLKQGYLYTTNQRNRLNTSVFQTKALGGKPFVVVTGKEGAEMFYNNDVVQREGM 75 Query: 98 GNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELR 157 I + I + +GK+ + + ++ + + L L Sbjct: 76 LPKRIVNTLAGKGAIHTVDGKKHVDRKALFMSLMTEGNLN----------YVRELTRTLW 125 Query: 158 KTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCN 217 + + +++ R+ ++ E+ + + + + Sbjct: 126 HANTQRMESMDEVNIYRESIVLLTKVGTRW--------AGVQAPPEDIERIATDMDIMID 177 Query: 218 NFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDN 277 +F L F G + + ++ + ++ + E N Sbjct: 178 SFRALGGAFKGYKASKEARRRVEDWLEEQIIETRKGNIHPPEGTALYE--FAHWEDYLGN 235 Query: 278 QKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSP 337 + +A + + +GL + ++P K++ E D Sbjct: 236 PMDSRTCAIDLMNTFRPLIA----INRFVSFGLHAMNENPITREKIKSEPD--------- 282 Query: 338 CMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHD 397 Y E++RY VP +P D F+ IP G + + HD Sbjct: 283 ---------YAYKFAQEVRRYYPFVPF-LPGKAKVDIDFQGVTIPAGVGLALDVYGTTHD 332 Query: 398 DKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGK----RICAGEGLARMELFLFLTTIL 453 + + +PN F P F +G+ +P G CAGE + + + + Sbjct: 333 ESLWDDPNEFRPERFETWDGS---PFDLIPQGGGDYWTNHRCAGEWITVIIMEETMKYFA 389 Query: 454 QNFNLKSVDDLKNLNTTAV 472 + + ++ ++ Sbjct: 390 EKITYDVPEQDLEVDLNSI 408 >3AWQ-A nrPDB Length = 415 Score = 89.8 bits (221), Expect = 2e-18, Method: Composition-based stats. Identities = 24/135 (17%), Positives = 48/135 (35%), Gaps = 8/135 (5%) Query: 342 RSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEF 401 Y + V E++R+ P V + D ++ P+G ++ L HD + Sbjct: 268 VQQPDYAELFVQEVRRFYPFFPAVVAR-ASQDFEWEGMAFPEGRQVVLDLYGSNHDAATW 326 Query: 402 PNPNIFDPGHFLDKNGNFKKSDYFMPFSAGK----RICAGEGLARMELFLFLTTILQNFN 457 +P F P F + + S F+P G C GE + + + ++ Sbjct: 327 ADPQEFRPERFRAWDED---SFNFIPQGGGDHYLGHRCPGEWIVLAIMKVAAHLLVNAMR 383 Query: 458 LKSVDDLKNLNTTAV 472 D +++ + Sbjct: 384 YDVPDQDLSIDFARL 398 >2RCM-A nrPDB Length = 495 Score = 79.0 bits (193), Expect = 4e-15, Method: Composition-based stats. Identities = 79/500 (15%), Positives = 142/500 (28%), Gaps = 95/500 (19%) Query: 19 LWRQSCRRRKLP------------------PGPTPLPIIGNM-----LQIDVKDICKSFT 55 + +++ + P PG LPI+G + D + Sbjct: 1 MAKKTSSGSETPDLTVATRTGSKDLPIRNIPGNYGLPIVGPIKDRWDYFYDQGAEEFFKS 60 Query: 56 NFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSG-------------RGNSPI 102 K V+ V + + V AL+D G+ F G Sbjct: 61 RIRKYNSTVYRVNM-PPGAFIAENPQVV--ALLD-GKSFPVLFDVDKVEKKDLLTGTYMP 116 Query: 103 SQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKAS 162 S +T G I+S + + + I Q L + L K Sbjct: 117 STELTGGYRILSYLDPSEPKHEKLKNLLFFLLKSSRNRIFPEFQATYSELFDSLEKE--- 173 Query: 163 PCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLL 222 + + F R Y T +K + N PLL Sbjct: 174 -LSLKGKADFGGSSDGTAFNFLARAFYGTNPADTKLKADAPGLITKWV----LFNLHPLL 228 Query: 223 IDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEF 282 P + L + + + + + + + + +E +K Sbjct: 229 SIGLPRVIEEPLIHTFSLPPALVKSDYQRLYEFFLESAGEIL------VEADKLG----I 278 Query: 283 NIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHP-----------EVTAKVQEEIDHVI 331 + E L A + +G + +L P +V ++ EEI VI Sbjct: 279 SREEATHN---LLFA-----TCFNTWGGMKIL-FPNMVKRIGRAGHQVHNRLAEEIRSVI 329 Query: 332 GRHR-SPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNY----LIPKGTT 386 + M M T +VV+E R+ V D ++ + G Sbjct: 330 KSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGR-AKKDLVIESHDAAFKVKAGEM 388 Query: 387 IMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGK---------RICAG 437 + D K F + F P F+ + G +K + +S G + CAG Sbjct: 389 LYGYQPLATRDPKIFDRADEFVPERFVGEEG--EKLLRHVLWSNGPETETPTVGNKQCAG 446 Query: 438 EGLARMELFLFLTTILQNFN 457 + + LF+ I + ++ Sbjct: 447 KDFVVLVARLFVIEIFRRYD 466 >3DBM-A nrPDB Length = 473 Score = 66.7 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 69/470 (14%), Positives = 141/470 (30%), Gaps = 60/470 (12%) Query: 23 SCRRRKLPPGPTPLPIIGNM-----LQIDVKDICKSFTNFSKVY-GPVFTVYFGMNPIV- 75 S + + PG +P + + F + + Y VF P V Sbjct: 4 SSKPLREIPGSYGIPFFQPIKDRLEYFYGTGGRDEYFRSRMQKYQSTVFRANMPPGPFVS 63 Query: 76 ----VFHGYEAVKEAL------IDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRR 125 V +A + ++ + F+G S ++T G ++S + Sbjct: 64 SNPKVIVLLDAKSFPILFDVSKVEKKDLFTG--TYMPSTKLTGGYRVLSYLDPSEPRHAQ 121 Query: 126 FSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKT--KASPCDPTFILGCAPCNVICSVVF 183 + + + L E L K + A + F Sbjct: 122 LKNLLFFMLKNSSNRVIPQFETTYTELFEGLEAELAKNGKAAFNDVGEQAAFRFLGRAYF 181 Query: 184 QKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSY 243 + + + L S W+ + N P L P + L + ++ Sbjct: 182 NSNPEE---------TKLGTSAPTLISSWV-LFNLAPTLDLGLPWFLQEPLLHTFRLPAF 231 Query: 244 IREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETT- 302 + + + ++ + EK + + N++ V G + Sbjct: 232 LIKSTYNKLYDYFQSVATPVME------QAEKLGVPKDEAVHNILFAVCFNTFGGVKILF 285 Query: 303 STTLRYGLLLLLKHPEVTAKVQEEIDHVIGR--HRSPCMQDRSHMPYTDAVVHEIQRYSD 360 TL++ L ++ + EEI I + ++ MP T +VV+E R Sbjct: 286 PNTLKWIGLA-GENLHTQ--LAEEIRGAIKSYGDGNVTLEAIEQMPLTKSVVYESLRIEP 342 Query: 361 LVPTGVPHAVTTDTKFRNYL----IPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKN 416 VP ++ ++ + KG + D K F P + P F+ Sbjct: 343 PVPPQYG-KAKSNFTIESHDATFEVKKGEMLFGYQPFATKDPKVFDRPEEYVPDRFVGDG 401 Query: 417 GNFKKSDYFMPFSAGK---------RICAGEGLARMELFLFLTTILQNFN 457 K ++ +S G + CAG+ + LF+ + + ++ Sbjct: 402 EALLK---YVWWSNGPETESPTVENKQCAGKDFVVLITRLFVIELFRRYD 448 >2YJN-B nrPDB Length = 381 Score = 58.6 bits (140), Expect = 7e-09, Method: Composition-based stats. Identities = 17/121 (14%), Positives = 40/121 (33%), Gaps = 19/121 (15%) Query: 291 VADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDA 350 AG E T+ T+ +L + P + ++ ++ Sbjct: 216 ALRALFAGAEMTANTVVDAVLAVSAEPGLAERIADDPAA------------------AQR 257 Query: 351 VVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPG 410 V E+ R + T + + ++I +G ++ ++ + D + F P+ D Sbjct: 258 TVAEVLRLHPALHLE-RRTATAEVRLGEHVIGEGEEVVVVVAAANRDPEVFAEPDRLDVD 316 Query: 411 H 411 Sbjct: 317 R 317 >4YXC-B nrPDB Length = 227 Score = 33.5 bits (75), Expect = 0.24, Method: Composition-based stats. Identities = 18/139 (12%), Positives = 40/139 (28%), Gaps = 26/139 (18%) Query: 253 ASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLL 312 NNP D L + + N++ ++ V G + + Sbjct: 90 EEQPKNNPSDENTGALDDLWADALNEQKATTTKSAADAVFQQLGGGD------VSGAM-- 141 Query: 313 LLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTT 372 ++ID ++ ++ + T + E+ R + + Sbjct: 142 ------------QDIDLIMDIPVKLTVE----LGRTRMTIKELLRLTQGSVVALDGLAGE 185 Query: 373 --DTKFRNYLIPKGTTIMA 389 D YLI +G ++ Sbjct: 186 PLDILINGYLIAQGEVVVV 204 >3GFZ-A nrPDB Length = 413 Score = 32.8 bits (73), Expect = 0.34, Method: Composition-based stats. Identities = 16/113 (14%), Positives = 36/113 (31%), Gaps = 17/113 (15%) Query: 315 KHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDT 374 +H +V +++ + + D + TD + EI R+S Sbjct: 78 RHRDVVELMRDYSAYRRFHGTGMRILDL-RLFETDGALEEILRFSTF------------- 123 Query: 375 KFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMP 427 P + LL++ + D + P P ++ + + +P Sbjct: 124 ---GVTEPVNDRMFRLLSAFIADGGRYCLPEPLQPSRWMMMPASGTAAPQHLP 173 >4YXB-D nrPDB Length = 80 Score = 32.4 bits (72), Expect = 0.41, Method: Composition-based stats. Identities = 8/48 (16%), Positives = 16/48 (33%), Gaps = 2/48 (4%) Query: 344 HMPYTDAVVHEIQRYSDLVPTGVPHAVTT--DTKFRNYLIPKGTTIMA 389 + T + E+ R + + D YLI +G ++ Sbjct: 10 ELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVV 57 >6FSZ-KK nrPDB Length = 733 Score = 32.4 bits (72), Expect = 0.46, Method: Composition-based stats. Identities = 23/121 (19%), Positives = 45/121 (37%), Gaps = 9/121 (7%) Query: 148 EAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRI 207 E ++E+L+ TK D + ++C + R ++++L + EN I Sbjct: 221 ELESMLEDLKNTKEIAVDLEHHDYRSYYGIVCLMQISTR----ERDYLVDTLKLRENLHI 276 Query: 208 LNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCF 267 LN + P ++ F G ++ Y+ + AS + PR + Sbjct: 277 LNEVFTN-----PSIVKVFHGAFMNIIWLQRDLGLYVVGLFDTYHASKAIGLPRHSLAYL 331 Query: 268 L 268 L Sbjct: 332 L 332 >2HBL-A nrPDB Length = 410 Score = 31.6 bits (70), Expect = 0.71, Method: Composition-based stats. Identities = 23/121 (19%), Positives = 45/121 (37%), Gaps = 9/121 (7%) Query: 148 EAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRI 207 E ++E+L+ TK D + ++C + R ++++L + EN I Sbjct: 95 ELESMLEDLKNTKEIAVDLEHHDYRSYYGIVCLMQISTR----ERDYLVDTLKLRENLHI 150 Query: 208 LNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCF 267 LN + P ++ F G ++ Y+ + AS + PR + Sbjct: 151 LNEVFTN-----PSIVKVFHGAFMDIIWLQRDLGLYVVGLFDTYHASKAIGLPRHSLAYL 205 Query: 268 L 268 L Sbjct: 206 L 206 >6HIW-DG nrPDB Length = 631 Score = 31.6 bits (70), Expect = 0.79, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 31/78 (39%), Gaps = 2/78 (2%) Query: 85 EALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDR 144 L D R + ++ + L +S + W+E RR L L N + +E Sbjct: 121 FLLFDELVALGARPDLAAAETLHTVLSHSASMPEEWREARRLQLVELYN-NLAMEEVERL 179 Query: 145 VQEEAHCLV-EELRKTKA 161 A L+ E++++ + Sbjct: 180 APHRADRLLKEQMKRFRG 197 >4DJD-D nrPDB Length = 323 Score = 31.2 bits (69), Expect = 1.00, Method: Composition-based stats. Identities = 14/47 (29%), Positives = 22/47 (46%), Gaps = 10/47 (21%) Query: 290 TVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRS 336 T L AG +LL++HPE A+V+E ID ++ + Sbjct: 287 TATALLQAGAH----------ILLMRHPEAVARVKENIDQLMVSNAY 323 >1GSQ-A nrPDB Length = 202 Score = 31.2 bits (69), Expect = 1.00, Method: Composition-based stats. Identities = 22/100 (22%), Positives = 43/100 (43%), Gaps = 12/100 (12%) Query: 63 PVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGR----GNSPI--SQRITKGLGIISSN 116 P +T+++ + E + L +GEEF+ R + P + + + ++ + Sbjct: 1 PKYTLHYFP----LMGRAELCRFVLAAHGEEFTDRVVEMADWPNLKATMYSNAMPVLDID 56 Query: 117 GKRWKEIRRFSLTTLRNFGM-GKRSIED-RVQEEAHCLVE 154 G + + + R FG+ GK S+E RV E L + Sbjct: 57 GTKMSQSMCIARHLAREFGLDGKTSLEKYRVDEITETLQD 96 >5L9W-B nrPDB Length = 732 Score = 30.1 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 14/89 (15%), Positives = 32/89 (35%), Gaps = 4/89 (4%) Query: 245 REKVKEHQASLDVNNPRDFID-CFLIKMEQEKDNQKS---EFNIENLVGTVADLFVAGTE 300 ++V E + N P I+ ++ + + D+ S + E++ + L G Sbjct: 115 GQRVAERRNIAVQNKPLPLIERDLILGVRERIDSSGSVVRPLDEEDVRTKLRMLMDRGAR 174 Query: 301 TTSTTLRYGLLLLLKHPEVTAKVQEEIDH 329 +L + + V ++EE Sbjct: 175 AIVVSLLWSFMNPAHEKRVREIIREEYKE 203 >4TKV-B nrPDB Length = 523 Score = 30.1 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 32/88 (36%), Gaps = 2/88 (2%) Query: 79 GYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMG- 137 G + E L+ E SG+ + L + ++ W +RF+L +F MG Sbjct: 321 GLDWTDEFLMKVSEI-SGQPIPASLTKERGRLVDMMTDSHTWLHGKRFALWGDPDFVMGL 379 Query: 138 KRSIEDRVQEEAHCLVEELRKTKASPCD 165 + + + E H L K D Sbjct: 380 VKFLLELGCEPVHILCHNGNKRWKKAVD 407 >6IGZ-A nrPDB Length = 751 Score = 29.3 bits (64), Expect = 3.5, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 28/77 (36%), Gaps = 6/77 (7%) Query: 20 WRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHG 79 + R L GPT I N L D D ++ + VF+ +FG I++ Sbjct: 30 AKPGHFSRTLAKGPTTTTWIWN-LHADAHDFDSHTSDLEDISRKVFSAHFGQLGIILIWL 88 Query: 80 YEAVKEALIDNGEEFSG 96 + +G FS Sbjct: 89 SG-----MYFHGARFSN 100 >3K7D-A nrPDB Length = 498 Score = 29.3 bits (64), Expect = 3.9, Method: Composition-based stats. Identities = 30/202 (14%), Positives = 60/202 (29%), Gaps = 15/202 (7%) Query: 124 RRFSLTTLRNFGMGKRSIEDR-VQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVV 182 R+ LT + +F ++ ++ R + +++ L S + +V Sbjct: 29 RKQVLTLIADF---RKELDKRTIGPRGRQVLDHLMPHLLSDVCAREDAAVTLSRITALLV 85 Query: 183 FQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRS 242 +L L+ F + L S L + N + Sbjct: 86 GIVTRT----TYLELLSEFPAALKHLISLCAASPMIASQLARYPLLLDELLDPNTLYQPT 141 Query: 243 YIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETT 302 E + L + P D + L + Q K Q ++ GT+ + V+ Sbjct: 142 ATDAYRDELRQYL-LRVPEDDEEQQLEALRQFKQAQLLRIAAADIAGTLPVMKVSDH--- 197 Query: 303 STTLRYGLLLLLKHPEVTAKVQ 324 L + ++ A VQ Sbjct: 198 ---LTWLAEAMIDAVVQQAWVQ 216 >1CLI-A nrPDB Length = 345 Score = 28.9 bits (63), Expect = 5.7, Method: Composition-based stats. Identities = 11/65 (16%), Positives = 25/65 (38%), Gaps = 8/65 (12%) Query: 370 VTTDTKFRNY--LIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMP 427 + IP+ ++ T + D+ + P +F+ +L GN + + + Sbjct: 244 AIAHLTGGGFWENIPR---VLPDNTQAVIDESSWQWPEVFN---WLQTAGNVEHHEMYRT 297 Query: 428 FSAGK 432 F+ G Sbjct: 298 FNCGV 302 >1SCZ-A nrPDB Length = 233 Score = 28.1 bits (61), Expect = 9.0, Method: Composition-based stats. Identities = 21/99 (21%), Positives = 34/99 (34%), Gaps = 7/99 (7%) Query: 52 KSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLG 111 K + K YG F G+ + +AV EAL E + + + Sbjct: 39 KPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVS 98 Query: 112 IISSNGKRWKEIRRFSLTTLRNF-GMGKRSIEDRVQEEA 149 + S R LR+ +G IE +++E A Sbjct: 99 MAVSTP------RGLVTPVLRDVDTLGMADIEKKIKELA 131 >4HE8-H nrPDB Length = 365 Score = 28.1 bits (61), Expect = 9.8, Method: Composition-based stats. Identities = 8/59 (13%), Positives = 21/59 (35%), Gaps = 4/59 (6%) Query: 295 FVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVH 353 V G T +++++ L + ++ +G P ++ +PY + Sbjct: 228 LVGGYHTEYSSIKWALFQMAEYIHFITASALIPTLFLGGWTMPVLE----VPYLWMFLK 282 >1O7A-A nrPDB Length = 515 Score = 28.1 bits (61), Expect = 9.8, Method: Composition-based stats. Identities = 20/130 (15%), Positives = 39/130 (30%), Gaps = 23/130 (17%) Query: 20 WRQSCRRRKLPPGPTPLPI----IGNMLQIDVKDICKSFT--------------NFSKVY 61 R K P PLP+ N+L + ++ S + F + + Sbjct: 2 ARAPSVSAKPGPALWPLPLSVKMTPNLLHLAPENFYISHSPNSTAGPSCTLLEEAFRRYH 61 Query: 62 GPVFTVYFGMNPIVVFHGYEAVKEALI-----DNGEEFSGRGNSPISQRITKGLGIISSN 116 G +F Y + F V++ L+ + F + + K + Sbjct: 62 GYIFGFYKWHHEPAEFQAKTQVQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKA 121 Query: 117 GKRWKEIRRF 126 + W +R Sbjct: 122 NRVWGALRGL 131 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.131 0.352 Lambda K H 0.267 0.0403 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,165,202 Number of Sequences: 36641 Number of extensions: 745086 Number of successful extensions: 3011 Number of sequences better than 10.0: 188 Number of HSP's better than 10.0 without gapping: 266 Number of HSP's successfully gapped in prelim test: 86 Number of HSP's that attempted gapping in prelim test: 2010 Number of HSP's gapped (non-prelim): 384 length of query: 490 length of database: 10,336,785 effective HSP length: 101 effective length of query: 389 effective length of database: 6,636,044 effective search space: 2581421116 effective search space used: 2581421116 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 61 (28.1 bits)