BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P10619 (480 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4CIB-A nrPDB 944 0.0 4MWT-A nrPDB 864 0.0 4AZ3-A nrPDB 620 e-178 4AZ3-B nrPDB 326 1e-89 1YSC-A nrPDB 179 3e-45 1BCR-A nrPDB 158 5e-39 1AC5-A nrPDB 139 3e-33 1GXS-A nrPDB 130 1e-30 1BCS-B nrPDB 60 2e-09 1GXS-B nrPDB 60 2e-09 1XRN-A nrPDB 36 0.036 4HXF-B nrPDB 33 0.37 5NW4-X nrPDB 30 3.3 4FAJ-A nrPDB 28 6.7 >4CIB-A nrPDB Length = 455 Score = 944 bits (2440), Expect = 0.0, Method: Compositional matrix adjust. Identities = 452/452 (100%), Positives = 452/452 (100%) Query: 29 APDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGC 88 APDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGC Sbjct: 3 APDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGC 62 Query: 89 SSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTE 148 SSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTE Sbjct: 63 SSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTE 122 Query: 149 VAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGL 208 VAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGL Sbjct: 123 VAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGL 182 Query: 209 SSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVG 268 SSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVG Sbjct: 183 SSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVG 242 Query: 269 NSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLRSGDKVRMD 328 NSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLRSGDKVRMD Sbjct: 243 NSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLRSGDKVRMD 302 Query: 329 PPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQ 388 PPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQ Sbjct: 303 PPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQ 362 Query: 389 KYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIA 448 KYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIA Sbjct: 363 KYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIA 422 Query: 449 FLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY 480 FLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY Sbjct: 423 FLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY 454 >4MWT-A nrPDB Length = 428 Score = 864 bits (2232), Expect = 0.0, Method: Compositional matrix adjust. Identities = 422/452 (93%), Positives = 422/452 (93%), Gaps = 30/452 (6%) Query: 29 APDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGC 88 APDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGC Sbjct: 1 APDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGC 60 Query: 89 SSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTE 148 SSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTE Sbjct: 61 SSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTE 120 Query: 149 VAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGL 208 VAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGL Sbjct: 121 VAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGL 180 Query: 209 SSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVG 268 SSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVG Sbjct: 181 SSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVG 240 Query: 269 NSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLRSGDKVRMD 328 NSGLNIYNLYAPCAGGVPSHF RSGDKVRMD Sbjct: 241 NSGLNIYNLYAPCAGGVPSHF------------------------------RSGDKVRMD 270 Query: 329 PPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQ 388 PPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQ Sbjct: 271 PPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQ 330 Query: 389 KYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIA 448 KYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIA Sbjct: 331 KYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIA 390 Query: 449 FLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY 480 FLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY Sbjct: 391 FLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY 422 >4AZ3-A nrPDB Length = 300 Score = 620 bits (1598), Expect = e-178, Method: Compositional matrix adjust. Identities = 298/298 (100%), Positives = 298/298 (100%) Query: 29 APDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGC 88 APDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGC Sbjct: 3 APDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGC 62 Query: 89 SSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTE 148 SSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTE Sbjct: 63 SSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTE 122 Query: 149 VAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGL 208 VAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGL Sbjct: 123 VAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGL 182 Query: 209 SSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVG 268 SSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVG Sbjct: 183 SSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVG 242 Query: 269 NSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLRSGDKVR 326 NSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLRSGDKVR Sbjct: 243 NSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLRSGDKVR 300 >4AZ3-B nrPDB Length = 155 Score = 326 bits (836), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 154/154 (100%), Positives = 154/154 (100%) Query: 327 MDPPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLS 386 MDPPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLS Sbjct: 1 MDPPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLS 60 Query: 387 SQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSH 446 SQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSH Sbjct: 61 SQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSH 120 Query: 447 IAFLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY 480 IAFLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY Sbjct: 121 IAFLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY 154 >1YSC-A nrPDB Length = 421 Score = 179 bits (453), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 143/466 (30%), Positives = 215/466 (46%), Gaps = 87/466 (18%) Query: 41 LAKQPSFRQYSGYLK-GSGSKHLHYWFVESQKDPENSPVVLWLNGGPGCSSLDGLLTEHG 99 L P+ QY+GYL KH +W ES+ DP PV+LWLNGGPGCSSL GL E G Sbjct: 8 LGIDPNVTQYTGYLDVEDEDKHFFFWTFESRNDPAKDPVILWLNGGPGCSSLTGLFFELG 67 Query: 100 PFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTEVAQSNFEALQD 159 P + PD + NPYSWN A V++L+ P VGFSYS +N + + L+ Sbjct: 68 PSSIGPDLKPIG-NPYSWNSNATVIFLDQPVNVGFSYSGSSG-VSNTVAAGKDVYNFLEL 125 Query: 160 FFRLFPEY--KNNKLFLTGESYAGIYIPTLA--VLVMQDPSMNLQGLAVGNGLSSYEQND 215 FF FPEY K + GESYAG YIP A +L +D + NL + +GNGL+ Sbjct: 126 FFDQFPEYVNKGQDFHIAGESYAGHYIPVFASEILSHKDRNFNLTSVLIGNGLT------ 179 Query: 216 NSLVYFAYYHGLLGNRLW--SSLQTHCCSQ-----NKC-----NFYDNKDL-ECV----- 257 + L + YY + S L + CS +C + YD++ + CV Sbjct: 180 DPLTQYNYYEPMACGEGGEPSVLPSEECSAMEDSLERCLGLIESCYDSQSVWSCVPATIY 239 Query: 258 TNLQEVARIVGNSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQA 317 N ++A +G N+Y++ C GG + +QD+ + Sbjct: 240 CNNAQLAP-YQRTGRNVYDIRKDCEGGNLCY-------PTLQDIDD-------------- 277 Query: 318 LLRSGDKVRMDPPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSM 377 YLN YV++A + ++ ++ CNF +N + M Sbjct: 278 ----------------------YLNQDYVKEA--VGAEVDHYESCNFDINRNFLFAGDWM 313 Query: 378 NSQYLKL--LSSQKYQILLYNGDVDMACNFMGDEWFVDSL----NQKMEVQR-RPWLVKY 430 + + L +Q IL+Y GD D CN++G++ + D L +++ Q+ R W Sbjct: 314 KPYHTAVTDLLNQDLPILVYAGDKDFICNWLGNKAWTDVLPWKYDEEFASQKVRNWTASI 373 Query: 431 GDSGEQIAGFVKEFSHIAFLTIKGAGHMVPTDKPLAAFTMFSRFLN 476 D ++AG VK + H +L + GHMVP D P A +M + +++ Sbjct: 374 TD---EVAGEVKSYKHFTYLRVFNGGHMVPFDVPENALSMVNEWIH 416 >1BCR-A nrPDB Length = 263 Score = 158 bits (399), Expect = 5e-39, Method: Compositional matrix adjust. Identities = 99/258 (38%), Positives = 146/258 (56%), Gaps = 20/258 (7%) Query: 33 DEIQRLPGLAKQPS--FRQYSGYL---KGSGSKHLHYWFVESQKDPENSPVVLWLNGGPG 87 D I RLPG QP+ F YSGY+ +G+G + L Y E+ +D + +P+VLWLNGGPG Sbjct: 9 DRIARLPG---QPAVDFDMYSGYITVDEGAG-RSLFYLLQEAPEDAQPAPLVLWLNGGPG 64 Query: 88 CSSLD-GLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSD--DKFYAT 144 CSS+ G E G F V+P G L N Y WN +ANVL+L+SPAGVGFSY++ Y + Sbjct: 65 CSSVAYGASEELGAFRVKPRGAGLVLNEYRWNKVANVLFLDSPAGVGFSYTNTSSDIYTS 124 Query: 145 NDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVM--QDPSMNLQGL 202 D A ++ L +F FP YK ++ GESYAG Y+P L+ LV ++P +NL+G Sbjct: 125 GDNRTAHDSYAFLAKWFERFPHYKYRDFYIAGESYAGHYVPELSQLVHRSKNPVINLKGF 184 Query: 203 AVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQE 262 VGNGL + F + HG++ + + L+ C + + + + T++ Sbjct: 185 MVGNGLIDDYHDYVGTFEFWWNHGIVSDDTYRRLKEACL--HDSFIHPSPACDAATDVAT 242 Query: 263 VARIVGNSGLNIYNLYAP 280 + GN +++Y+LY P Sbjct: 243 AEQ--GN--IDMYSLYTP 256 >1AC5-A nrPDB Length = 483 Score = 139 bits (349), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 126/479 (26%), Positives = 214/479 (44%), Gaps = 79/479 (16%) Query: 36 QRLPGLAKQPSF----RQYSGYL-------KGSGSKHLHYWFVESQKDPENS----PVVL 80 + LPGL++ P + ++G++ S L Y+F + + N P+++ Sbjct: 12 ELLPGLSEVPDPSNIPQMHAGHIPLRSEDADEQDSSDLEYFFWKFTNNDSNGNVDRPLII 71 Query: 81 WLNGGPGCSSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDK 140 WLNGGPGCSS+DG L E GPF V DG L N SW ++L+++ P G GFS +K Sbjct: 72 WLNGGPGCSSMDGALVESGPFRVNSDG-KLYLNEGSWISKGDLLFIDQPTGTGFSVEQNK 130 Query: 141 FYATNDT--------EVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVM 192 D +V + + L+++F++FPE K+ L+GESYAG YIP A ++ Sbjct: 131 DEGKIDKNKFDEDLEDVTKHFMDFLENYFKIFPEDLTRKIILSGESYAGQYIPFFANAIL 190 Query: 193 QD--------PSMNLQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQN 244 + +L+ L +GNG + N SL Y + +++ ++ Sbjct: 191 NHNKFSKIDGDTYDLKALLIGNGW--IDPNTQSLSYLPF-----------AMEKKLIDES 237 Query: 245 KCNFYDNKDLECVTNLQEVARIVGNSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNI 304 NF + +TN E N NL + +HF Y++ ++ L + Sbjct: 238 NPNF------KHLTNAHE----------NCQNLINSASTDEAAHFSYQECENILNLLLS- 280 Query: 305 FTRLPLKR-------MWHQALLRSGDKVRMDPPCTNTTAASTYLNNPYVRKALNI-PEQL 356 +TR ++ M++ L S M+ P + + S + + P V +L++ +++ Sbjct: 281 YTRESSQKGTADCLNMYNFNLKDSYPSCGMNWP-KDISFVSKFFSTPGVIDSLHLDSDKI 339 Query: 357 PQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQKYQILLYNGDVDMACNFMGDEWFVDSLN 416 W C V + + L L +I+L+NGD D+ CN G +D+L Sbjct: 340 DHWKECTNSVGTKLSNPISKPSIHLLPGLLESGIEIVLFNGDKDLICNNKGVLDTIDNLK 399 Query: 417 Q------KMEVQRRPWL--VKYGDSGEQIAGFVKEFSHIAFLTIKGAGHMVPTDKPLAA 467 + W+ K D E+ +G+VK ++ F+++ A HMVP DK L + Sbjct: 400 WGGIKGFSDDAVSFDWIHKSKSTDDSEEFSGYVKYDRNLTFVSVYNASHMVPFDKSLVS 458 >1GXS-A nrPDB Length = 270 Score = 130 bits (328), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 90/269 (33%), Positives = 139/269 (51%), Gaps = 17/269 (6%) Query: 31 DQDEIQRLPGLAKQPSFRQYSGY--LKGSGSKHLHYWFVESQKDPENSP-VVLWLNGGPG 87 + D I LPG +F Y GY + + + L+YWF E+ + +VLWLNGGPG Sbjct: 6 EDDRILGLPGQPNGVAFGMYGGYVTIDDNNGRALYYWFQEADTADPAAAPLVLWLNGGPG 65 Query: 88 CSSLD-GLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKF-YATN 145 CSS+ G + E G F V +G +L N Y+WN AN+L+ ESPAGVGFSYS+ + Sbjct: 66 CSSIGLGAMQELGAFRVHTNGESLLLNEYAWNKAANILFAESPAGVGFSYSNTSSDLSMG 125 Query: 146 DTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQD----PSMNLQG 201 D ++AQ + L +F FP Y + ++ GES G +IP L+ +V ++ P +N QG Sbjct: 126 DDKMAQDTYTFLVKWFERFPHYNYREFYIAGES--GHFIPQLSQVVYRNRNNSPFINFQG 183 Query: 202 LAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQ 261 L V +GL++ ++ + ++HGL+ + S C + + + EC Sbjct: 184 LLVSSGLTNDHEDMIGMFESWWHHGLISDETRDSGLKVCPGTS----FMHPTPECTEVWN 239 Query: 262 EVARIVGNSGLNIYNLYAPCAGGVPSHFR 290 + GN +N Y +Y P PS ++ Sbjct: 240 KALAEQGN--INPYTIYTPTCDREPSPYQ 266 >1BCS-B nrPDB Length = 160 Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 39/153 (25%), Positives = 72/153 (47%), Gaps = 10/153 (6%) Query: 330 PCTNTTAASTYLNNPYVRKAL--NIPEQLP-QWDMCNFLVNLQYRRLYRSMNSQYLKLLS 386 PCT ++ Y N V+ AL N+ + W C+ +N + RSM Y +L++ Sbjct: 6 PCTER-YSTAYYNRRDVQMALHANVTGAMNYTWATCSDTINTHWHDAPRSMLPIYRELIA 64 Query: 387 SQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSH 446 + +I +++GD D + + +L PW Y D +++ G+ + + Sbjct: 65 A-GLRIWVFSGDTDAVVPLTATRYSIGALGLPTTTSWYPW---YDD--QEVGGWSQVYKG 118 Query: 447 IAFLTIKGAGHMVPTDKPLAAFTMFSRFLNKQP 479 + ++++GAGH VP +P A +F FL +P Sbjct: 119 LTLVSVRGAGHEVPLHRPRQALVLFQYFLQGKP 151 >1GXS-B nrPDB Length = 158 Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 36/145 (24%), Positives = 72/145 (49%), Gaps = 10/145 (6%) Query: 340 YLNNPYVRKALN-----IPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQKYQILL 394 YLN P V+ AL+ I E W +C+ + Q+ + + Y +L+ + ++ + Sbjct: 15 YLNLPEVQTALHANVSGIVEY--PWTVCSNTIFDQWGQAADDLLPVYRELIQA-GLRVWV 71 Query: 395 YNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIAFLTIKG 454 Y+GD D + +L ++ PW + + ++ G+ ++ + ++T++G Sbjct: 72 YSGDTDSVVPVSSTRRSLAALELPVKTSWYPWYM--APTEREVGGWSVQYEGLTYVTVRG 129 Query: 455 AGHMVPTDKPLAAFTMFSRFLNKQP 479 AGH+VP +P AF +F +FL +P Sbjct: 130 AGHLVPVHRPAQAFLLFKQFLKGEP 154 >1XRN-A nrPDB Length = 293 Score = 36.2 bits (82), Expect = 0.036, Method: Compositional matrix adjust. Identities = 48/147 (32%), Positives = 68/147 (46%), Gaps = 29/147 (19%) Query: 64 YWFVESQKDPENSPVVLWLNGGPGCSSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANV 123 Y + + K PE ++ ++GGPG S D LL+ + +G+T V Sbjct: 16 YIYYKLCKAPEEKAKLMTMHGGPGMSH-DYLLSLRD---MTKEGIT-------------V 58 Query: 124 LYLESPAGVGFSYSDDKFYATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIY 183 L+ + G G S D+ T D V ++ EAL+ +LF N K+FL G SY G Sbjct: 59 LFYDQ-FGCGRSEEPDQSKFTIDYGVEEA--EALRS--KLFG---NEKVFLMGSSYGGAL 110 Query: 184 IPTLAVLVMQDPSMNLQGLAVGNGLSS 210 AV QD +L+GL V GLSS Sbjct: 111 ALAYAV-KYQD---HLKGLIVSGGLSS 133 >4HXF-B nrPDB Length = 622 Score = 32.7 bits (73), Expect = 0.37, Method: Compositional matrix adjust. Identities = 30/125 (24%), Positives = 57/125 (45%), Gaps = 29/125 (23%) Query: 65 WFVESQ-KDPENSPVVLWLNGGPGCSSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIAN- 122 W+++ + K+ E +PV+++++GGP G+ Y Y L+A+ Sbjct: 366 WYIKPEIKEGEKAPVIVFVHGGP-------------------KGMYGYYFKYEMQLMASK 406 Query: 123 ---VLYLESPAGVGFSYSDD---KFYATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTG 176 ++Y+ +P G YS+D + E Q +++F RL P+ ++ +TG Sbjct: 407 GYYIVYV-NPRGSN-GYSEDFALRVLERTGLEDFQDILNGIEEFLRLEPQADRERIGITG 464 Query: 177 ESYAG 181 SY G Sbjct: 465 ISYGG 469 >5NW4-X nrPDB Length = 417 Score = 29.6 bits (65), Expect = 3.3, Method: Compositional matrix adjust. Identities = 15/65 (23%), Positives = 34/65 (52%), Gaps = 3/65 (4%) Query: 388 QKYQILLYNGDVDMACNFMGD---EWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEF 444 +K +++ G+ C F G+ + S+ +K + + +V+Y + E++ ++KEF Sbjct: 12 EKTAVVIDLGEAFTKCGFAGETGPRCIIPSVIKKAGMPKPIKVVQYNINTEELYSYLKEF 71 Query: 445 SHIAF 449 HI + Sbjct: 72 IHILY 76 >4FAJ-A nrPDB Length = 564 Score = 28.5 bits (62), Expect = 6.7, Method: Compositional matrix adjust. Identities = 30/117 (25%), Positives = 45/117 (38%), Gaps = 32/117 (27%) Query: 240 CCSQNKCNFYDNKDLEC-VTNLQEVARIVGNSGLNIYNL----YAPCAGGVPSHFRYEKD 294 S+NK ++D KD+ N Q V I N+G+N+YN AP AG ++ +K+ Sbjct: 254 TISKNK-EYWDQKDVSMDKINFQVVKEI--NTGINLYNDGQLDEAPLAGEYAKQYKKDKE 310 Query: 295 TVVVQDLGNIFTRLPLKRMWHQALLRSGDKVRMDPPCTNTTAASTYLNNPYVRKALN 351 +F + N T + L N VRKA+N Sbjct: 311 YSTTLMANTMFLEM------------------------NQTGENKLLQNKNVRKAIN 343 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4CIB-A nrPDB 691 0.0 4MWT-A nrPDB 641 0.0 4AZ3-A nrPDB 456 e-128 1AC5-A nrPDB 456 e-128 1YSC-A nrPDB 428 e-120 1BCR-A nrPDB 324 4e-89 1GXS-A nrPDB 324 6e-89 4AZ3-B nrPDB 240 1e-63 1BCS-B nrPDB 185 4e-47 1GXS-B nrPDB 175 6e-44 Sequences not found previously or not previously below threshold: 4Q1V-A nrPDB 35 0.096 2WNW-A nrPDB 32 0.39 4IQB-A nrPDB 32 0.40 3MXU-A nrPDB 32 0.60 4EIN-A nrPDB 30 1.9 4GYH-A nrPDB 30 2.8 5CUY-A nrPDB 30 3.0 1TSX-A nrPDB 29 3.6 2QR4-A nrPDB 29 3.9 5C5V-A nrPDB 29 4.4 6IDN-A nrPDB 28 9.1 CONVERGED! >4CIB-A nrPDB Length = 455 Score = 691 bits (1784), Expect = 0.0, Method: Composition-based stats. Identities = 452/452 (100%), Positives = 452/452 (100%) Query: 29 APDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGC 88 APDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGC Sbjct: 3 APDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGC 62 Query: 89 SSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTE 148 SSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTE Sbjct: 63 SSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTE 122 Query: 149 VAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGL 208 VAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGL Sbjct: 123 VAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGL 182 Query: 209 SSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVG 268 SSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVG Sbjct: 183 SSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVG 242 Query: 269 NSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLRSGDKVRMD 328 NSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLRSGDKVRMD Sbjct: 243 NSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLRSGDKVRMD 302 Query: 329 PPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQ 388 PPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQ Sbjct: 303 PPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQ 362 Query: 389 KYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIA 448 KYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIA Sbjct: 363 KYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIA 422 Query: 449 FLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY 480 FLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY Sbjct: 423 FLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY 454 >4MWT-A nrPDB Length = 428 Score = 641 bits (1652), Expect = 0.0, Method: Composition-based stats. Identities = 422/452 (93%), Positives = 422/452 (93%), Gaps = 30/452 (6%) Query: 29 APDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGC 88 APDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGC Sbjct: 1 APDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGC 60 Query: 89 SSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTE 148 SSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTE Sbjct: 61 SSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTE 120 Query: 149 VAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGL 208 VAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGL Sbjct: 121 VAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGL 180 Query: 209 SSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVG 268 SSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVG Sbjct: 181 SSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVG 240 Query: 269 NSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLRSGDKVRMD 328 NSGLNIYNLYAPCAGGVPSHF RSGDKVRMD Sbjct: 241 NSGLNIYNLYAPCAGGVPSHF------------------------------RSGDKVRMD 270 Query: 329 PPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQ 388 PPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQ Sbjct: 271 PPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQ 330 Query: 389 KYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIA 448 KYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIA Sbjct: 331 KYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIA 390 Query: 449 FLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY 480 FLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY Sbjct: 391 FLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY 422 >4AZ3-A nrPDB Length = 300 Score = 456 bits (1172), Expect = e-128, Method: Composition-based stats. Identities = 298/298 (100%), Positives = 298/298 (100%) Query: 29 APDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGC 88 APDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGC Sbjct: 3 APDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGC 62 Query: 89 SSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTE 148 SSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTE Sbjct: 63 SSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTE 122 Query: 149 VAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGL 208 VAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGL Sbjct: 123 VAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGL 182 Query: 209 SSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVG 268 SSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVG Sbjct: 183 SSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVG 242 Query: 269 NSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLRSGDKVR 326 NSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLRSGDKVR Sbjct: 243 NSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLRSGDKVR 300 >1AC5-A nrPDB Length = 483 Score = 456 bits (1172), Expect = e-128, Method: Composition-based stats. Identities = 126/479 (26%), Positives = 214/479 (44%), Gaps = 79/479 (16%) Query: 36 QRLPGLAKQPSF----RQYSGYL-------KGSGSKHLHYWFVESQKDPENS----PVVL 80 + LPGL++ P + ++G++ S L Y+F + + N P+++ Sbjct: 12 ELLPGLSEVPDPSNIPQMHAGHIPLRSEDADEQDSSDLEYFFWKFTNNDSNGNVDRPLII 71 Query: 81 WLNGGPGCSSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDK 140 WLNGGPGCSS+DG L E GPF V DG L N SW ++L+++ P G GFS +K Sbjct: 72 WLNGGPGCSSMDGALVESGPFRVNSDG-KLYLNEGSWISKGDLLFIDQPTGTGFSVEQNK 130 Query: 141 FYATNDT--------EVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVM 192 D +V + + L+++F++FPE K+ L+GESYAG YIP A ++ Sbjct: 131 DEGKIDKNKFDEDLEDVTKHFMDFLENYFKIFPEDLTRKIILSGESYAGQYIPFFANAIL 190 Query: 193 QD--------PSMNLQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQN 244 + +L+ L +GNG + N SL Y + +++ ++ Sbjct: 191 NHNKFSKIDGDTYDLKALLIGNGW--IDPNTQSLSYLPF-----------AMEKKLIDES 237 Query: 245 KCNFYDNKDLECVTNLQEVARIVGNSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNI 304 NF + +TN E N NL + +HF Y++ ++ L + Sbjct: 238 NPNF------KHLTNAHE----------NCQNLINSASTDEAAHFSYQECENILNLLLS- 280 Query: 305 FTRLPLKR-------MWHQALLRSGDKVRMDPPCTNTTAASTYLNNPYVRKALNI-PEQL 356 +TR ++ M++ L S M+ P + + S + + P V +L++ +++ Sbjct: 281 YTRESSQKGTADCLNMYNFNLKDSYPSCGMNWP-KDISFVSKFFSTPGVIDSLHLDSDKI 339 Query: 357 PQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQKYQILLYNGDVDMACNFMGDEWFVDSLN 416 W C V + + L L +I+L+NGD D+ CN G +D+L Sbjct: 340 DHWKECTNSVGTKLSNPISKPSIHLLPGLLESGIEIVLFNGDKDLICNNKGVLDTIDNLK 399 Query: 417 Q------KMEVQRRPWL--VKYGDSGEQIAGFVKEFSHIAFLTIKGAGHMVPTDKPLAA 467 + W+ K D E+ +G+VK ++ F+++ A HMVP DK L + Sbjct: 400 WGGIKGFSDDAVSFDWIHKSKSTDDSEEFSGYVKYDRNLTFVSVYNASHMVPFDKSLVS 458 >1YSC-A nrPDB Length = 421 Score = 428 bits (1101), Expect = e-120, Method: Composition-based stats. Identities = 143/467 (30%), Positives = 212/467 (45%), Gaps = 87/467 (18%) Query: 41 LAKQPSFRQYSGYLK-GSGSKHLHYWFVESQKDPENSPVVLWLNGGPGCSSLDGLLTEHG 99 L P+ QY+GYL KH +W ES+ DP PV+LWLNGGPGCSSL GL E G Sbjct: 8 LGIDPNVTQYTGYLDVEDEDKHFFFWTFESRNDPAKDPVILWLNGGPGCSSLTGLFFELG 67 Query: 100 PFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTEVAQSNFEALQD 159 P + PD + NPYSWN A V++L+ P VGFSYS +N + + L+ Sbjct: 68 PSSIGPDLKPIG-NPYSWNSNATVIFLDQPVNVGFSYSGSSG-VSNTVAAGKDVYNFLEL 125 Query: 160 FFRLFPEY--KNNKLFLTGESYAGIYIPTLA--VLVMQDPSMNLQGLAVGNGLSSYEQND 215 FF FPEY K + GESYAG YIP A +L +D + NL + +GNGL+ Sbjct: 126 FFDQFPEYVNKGQDFHIAGESYAGHYIPVFASEILSHKDRNFNLTSVLIGNGLTD----- 180 Query: 216 NSLVYFAYYHGLLGNRLW--SSLQTHCCSQ-----NKC-----NFYDNKDL-ECV----- 257 L + YY + S L + CS +C + YD++ + CV Sbjct: 181 -PLTQYNYYEPMACGEGGEPSVLPSEECSAMEDSLERCLGLIESCYDSQSVWSCVPATIY 239 Query: 258 TNLQEVARIVGNSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQA 317 N ++A +G N+Y++ C GG + +QD+ + Sbjct: 240 CNNAQLAP-YQRTGRNVYDIRKDCEGGNLCY-------PTLQDIDD-------------- 277 Query: 318 LLRSGDKVRMDPPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSM 377 YLN YV++A + ++ ++ CNF +N + M Sbjct: 278 ----------------------YLNQDYVKEA--VGAEVDHYESCNFDINRNFLFAGDWM 313 Query: 378 NSQYLKL--LSSQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQR-----RPWLVKY 430 + + L +Q IL+Y GD D CN++G++ + D L K + + R W Sbjct: 314 KPYHTAVTDLLNQDLPILVYAGDKDFICNWLGNKAWTDVLPWKYDEEFASQKVRNWTASI 373 Query: 431 GDSGEQIAGFVKEFSHIAFLTIKGAGHMVPTDKPLAAFTMFSRFLNK 477 D ++AG VK + H +L + GHMVP D P A +M + +++ Sbjct: 374 TD---EVAGEVKSYKHFTYLRVFNGGHMVPFDVPENALSMVNEWIHG 417 >1BCR-A nrPDB Length = 263 Score = 324 bits (831), Expect = 4e-89, Method: Composition-based stats. Identities = 96/265 (36%), Positives = 140/265 (52%), Gaps = 17/265 (6%) Query: 26 GEAAPDQDEIQRLPGLAKQPSFRQYSGYL--KGSGSKHLHYWFVESQKDPENSPVVLWLN 83 G AA D I RLPG F YSGY+ + L Y E+ +D + +P+VLWLN Sbjct: 5 GHAA---DRIARLPGQP-AVDFDMYSGYITVDEGAGRSLFYLLQEAPEDAQPAPLVLWLN 60 Query: 84 GGPGCSSLD-GLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKF- 141 GGPGCSS+ G E G F V+P G L N Y WN +ANVL+L+SPAGVGFSY++ Sbjct: 61 GGPGCSSVAYGASEELGAFRVKPRGAGLVLNEYRWNKVANVLFLDSPAGVGFSYTNTSSD 120 Query: 142 -YATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVM--QDPSMN 198 Y + D A ++ L +F FP YK ++ GESYAG Y+P L+ LV ++P +N Sbjct: 121 IYTSGDNRTAHDSYAFLAKWFERFPHYKYRDFYIAGESYAGHYVPELSQLVHRSKNPVIN 180 Query: 199 LQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVT 258 L+G VGNGL + F + HG++ + + L+ C + + + + T Sbjct: 181 LKGFMVGNGLIDDYHDYVGTFEFWWNHGIVSDDTYRRLKEACL--HDSFIHPSPACDAAT 238 Query: 259 NLQEVARIVGNSGLNIYNLYAPCAG 283 ++ + +++Y+LY P Sbjct: 239 DVATAEQ----GNIDMYSLYTPVCN 259 >1GXS-A nrPDB Length = 270 Score = 324 bits (829), Expect = 6e-89, Method: Composition-based stats. Identities = 90/269 (33%), Positives = 139/269 (51%), Gaps = 17/269 (6%) Query: 31 DQDEIQRLPGLAKQPSFRQYSGY--LKGSGSKHLHYWFVESQKDPENSP-VVLWLNGGPG 87 + D I LPG +F Y GY + + + L+YWF E+ + +VLWLNGGPG Sbjct: 6 EDDRILGLPGQPNGVAFGMYGGYVTIDDNNGRALYYWFQEADTADPAAAPLVLWLNGGPG 65 Query: 88 CSSLD-GLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSD-DKFYATN 145 CSS+ G + E G F V +G +L N Y+WN AN+L+ ESPAGVGFSYS+ + Sbjct: 66 CSSIGLGAMQELGAFRVHTNGESLLLNEYAWNKAANILFAESPAGVGFSYSNTSSDLSMG 125 Query: 146 DTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQD----PSMNLQG 201 D ++AQ + L +F FP Y + ++ GES G +IP L+ +V ++ P +N QG Sbjct: 126 DDKMAQDTYTFLVKWFERFPHYNYREFYIAGES--GHFIPQLSQVVYRNRNNSPFINFQG 183 Query: 202 LAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQ 261 L V +GL++ ++ + ++HGL+ + S C + + + EC Sbjct: 184 LLVSSGLTNDHEDMIGMFESWWHHGLISDETRDSGLKVCPGTS----FMHPTPECTEVWN 239 Query: 262 EVARIVGNSGLNIYNLYAPCAGGVPSHFR 290 + GN +N Y +Y P PS ++ Sbjct: 240 KALAEQGN--INPYTIYTPTCDREPSPYQ 266 >4AZ3-B nrPDB Length = 155 Score = 240 bits (611), Expect = 1e-63, Method: Composition-based stats. Identities = 154/154 (100%), Positives = 154/154 (100%) Query: 327 MDPPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLS 386 MDPPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLS Sbjct: 1 MDPPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLS 60 Query: 387 SQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSH 446 SQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSH Sbjct: 61 SQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSH 120 Query: 447 IAFLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY 480 IAFLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY Sbjct: 121 IAFLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY 154 >1BCS-B nrPDB Length = 160 Score = 185 bits (469), Expect = 4e-47, Method: Composition-based stats. Identities = 36/153 (23%), Positives = 70/153 (45%), Gaps = 10/153 (6%) Query: 330 PCTNTTAASTYLNNPYVRKALN--IPEQLP-QWDMCNFLVNLQYRRLYRSMNSQYLKLLS 386 PCT ++ Y N V+ AL+ + + W C+ +N + RSM Y +L++ Sbjct: 6 PCTER-YSTAYYNRRDVQMALHANVTGAMNYTWATCSDTINTHWHDAPRSMLPIYRELIA 64 Query: 387 SQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSH 446 + +I +++GD D + + +L PW +++ G+ + + Sbjct: 65 A-GLRIWVFSGDTDAVVPLTATRYSIGALGLPTTTSWYPWY-----DDQEVGGWSQVYKG 118 Query: 447 IAFLTIKGAGHMVPTDKPLAAFTMFSRFLNKQP 479 + ++++GAGH VP +P A +F FL +P Sbjct: 119 LTLVSVRGAGHEVPLHRPRQALVLFQYFLQGKP 151 >1GXS-B nrPDB Length = 158 Score = 175 bits (442), Expect = 6e-44, Method: Composition-based stats. Identities = 36/153 (23%), Positives = 75/153 (49%), Gaps = 7/153 (4%) Query: 330 PCTNTTAASTYLNNPYVRKALN--IPEQLP-QWDMCNFLVNLQYRRLYRSMNSQYLKLLS 386 PC + YLN P V+ AL+ + + W +C+ + Q+ + + Y +L+ Sbjct: 6 PCA-VFNSINYLNLPEVQTALHANVSGIVEYPWTVCSNTIFDQWGQAADDLLPVYRELIQ 64 Query: 387 SQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSH 446 + ++ +Y+GD D + +L ++ PW + + ++ G+ ++ Sbjct: 65 A-GLRVWVYSGDTDSVVPVSSTRRSLAALELPVKTSWYPWYM--APTEREVGGWSVQYEG 121 Query: 447 IAFLTIKGAGHMVPTDKPLAAFTMFSRFLNKQP 479 + ++T++GAGH+VP +P AF +F +FL +P Sbjct: 122 LTYVTVRGAGHLVPVHRPAQAFLLFKQFLKGEP 154 >4Q1V-A nrPDB Length = 710 Score = 34.8 bits (78), Expect = 0.096, Method: Composition-based stats. Identities = 32/208 (15%), Positives = 76/208 (36%), Gaps = 33/208 (15%) Query: 47 FRQYSGYLKG-SGSKHLHYWFVESQKDPENS--PVVLWLNGGPGCSSLDGLLTEHGPFLV 103 +G +K G+ LHY ++ PV++++ GGP + G Sbjct: 457 PSIETGTIKAADGTTDLHYRLMKPANFDPAKKYPVIVYVYGGPHAQCVTGGWQN------ 510 Query: 104 QPDGVTLEYNPYSWNLIANVLY-LES--PAGVGFSYSDDKFYATNDTEVAQSNFEALQDF 160 G +++ +++ + G ++ + F E + + ++ F Sbjct: 511 GARGWDTYM-----ASKGYIMFTIDNRGSSNRGLTFENATFRRLG-IEEGKDQVKGVE-F 563 Query: 161 FRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGLSSYEQNDNSLVY 220 + P + ++ + G S+ G L+++ P + G+A G ++ Sbjct: 564 LKSLPYVDSERIGVHGWSFGGHMT---TALMLRYPEIFKVGVAGG-----------PVID 609 Query: 221 FAYYHGLLGNRLWSSLQTHCCSQNKCNF 248 + YY + G R + +++ +CN Sbjct: 610 WGYYEIMYGERYMDTPESNPEGYKECNL 637 >2WNW-A nrPDB Length = 447 Score = 32.5 bits (72), Expect = 0.39, Method: Composition-based stats. Identities = 19/112 (16%), Positives = 37/112 (33%), Gaps = 12/112 (10%) Query: 324 KVRMDPPCTNTTAASTYLNNPYVRKALNI---PEQLPQWDMCNFLVNLQYRRLYRSMNSQ 380 + D Y + +AL++ P + WD C + V + + Sbjct: 165 ECYADWADIIINYLLEYRRHGINVQALSVQNEPVAVKTWDSCLYSVEEETAFAVQ----Y 220 Query: 381 YLKLLSSQK---YQILLYNGDVDMACNFMGDEWFVDSLNQK-MEVQRRPWLV 428 L+ Q +I +++ D D ++ + F D N K + W Sbjct: 221 LRPRLARQGMDEMEIYIWDHDKDGLVDW-AELAFADEANYKGINGLAFHWYT 271 >4IQB-A nrPDB Length = 315 Score = 32.5 bits (72), Expect = 0.40, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 19/57 (33%) Query: 383 KLLSSQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAG 439 KLL + +I NGD N L Q R + KY D +G Sbjct: 101 KLLMEKNVKIWEKNGDRAFLDNLGFTSREEGDLGPVYGFQWRHFGAKYVDCHTDYSG 157 >3MXU-A nrPDB Length = 143 Score = 32.1 bits (71), Expect = 0.60, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 26/74 (35%) Query: 85 GPGCSSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYAT 144 GPG S +H V+ VT+ Y+ + ++++++ P D Sbjct: 18 GPGSMSKTYFTQDHEWLSVEGQVVTVGITDYAQEQLGDLVFIDLPQNGTKLSKGDAAAVV 77 Query: 145 NDTEVAQSNFEALQ 158 + A + L Sbjct: 78 ESVKAASDVYAPLD 91 >4EIN-A nrPDB Length = 307 Score = 30.2 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 19/55 (34%) Query: 385 LSSQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAG 439 LSS+ +I NG D + L Q R + +Y D +G Sbjct: 95 LSSKGVRIWDANGSRDFLDSLGFSARQEGDLGPVYGFQWRHFGAEYKDMDSDYSG 149 >4GYH-A nrPDB Length = 318 Score = 29.8 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 19/55 (34%) Query: 385 LSSQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAG 439 LSS+ +I NG D + L Q R + +Y D +G Sbjct: 101 LSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSG 155 >5CUY-A nrPDB Length = 414 Score = 29.8 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 10/63 (15%), Positives = 25/63 (39%), Gaps = 3/63 (4%) Query: 230 NRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVGNSGLNIYNLYAPCAGGVPSHF 289 + + C S + + +D+ ++ + ++ + +Y C GG SHF Sbjct: 323 DEGEMDWKVVCISHSDPICHFLRDIH---DVPKFLPGCLDAIREWFRVYKICQGGEASHF 379 Query: 290 RYE 292 ++ Sbjct: 380 AFD 382 >1TSX-A nrPDB Length = 316 Score = 29.4 bits (64), Expect = 3.6, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 24/68 (35%), Gaps = 4/68 (5%) Query: 413 DSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIAFLTIKGAGHMVPTDKPLAAF---- 468 L Q R W GD+ +Q+ +++ + P D P A Sbjct: 140 GDLGLVYGSQWRAWHTSKGDTIDQLGDVIEQIKTHPYSRELIVSAWNPEDVPTMALPPCH 199 Query: 469 TMFSRFLN 476 T++ ++N Sbjct: 200 TLYQFYVN 207 >2QR4-A nrPDB Length = 587 Score = 29.4 bits (64), Expect = 3.9, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 39/112 (34%), Gaps = 9/112 (8%) Query: 272 LNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLRSGDKVRMDPPC 331 L++Y+LY P G P F YE+ + + + R D V Sbjct: 279 LHMYDLYTPVLGEAPITFTYEEAKEKALEALKPMGEEYMAIVEKAFSERWIDVVENKGKR 338 Query: 332 TNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLK 383 + ++ +Y NPY+ L W + + S++S + + Sbjct: 339 SGAYSSGSYDTNPYI---------LLNWHDTLDQLFTLVHEMGHSVHSYFTR 381 >5C5V-A nrPDB Length = 342 Score = 29.0 bits (63), Expect = 4.4, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 24/63 (38%), Gaps = 3/63 (4%) Query: 230 NRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVGNSGLNIYNLYAPCAGGVPSHF 289 + + C S N KD+ ++ + ++ + +Y C GG SHF Sbjct: 251 DEGKMDWKVVCISHNDPICRFMKDIH---DVPKFLPGCLDAIREWFRVYKICQGGEASHF 307 Query: 290 RYE 292 ++ Sbjct: 308 AFD 310 >6IDN-A nrPDB Length = 272 Score = 27.9 bits (60), Expect = 9.1, Method: Composition-based stats. Identities = 20/125 (16%), Positives = 39/125 (31%), Gaps = 1/125 (0%) Query: 205 GNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVA 264 GN S + S+ + + + L G L + D + T +++ Sbjct: 83 GNYYLSSRDDAASVAQYLWNNFLGGQSESRPLGDESLDGIDFDIEDGSNDYYDTLAEQLW 142 Query: 265 RIVGNSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLRSGDK 324 + G SG N+Y AP P ++ E + D + + + + Sbjct: 143 ILGGRSGSNVYLAAAPAC-EFPDYYLREAINTSLFDYVWVQFYNNPRCHYLGNATNLLNS 201 Query: 325 VRMDP 329 D Sbjct: 202 WNNDW 206 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.122 0.328 Lambda K H 0.267 0.0373 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,627,605 Number of Sequences: 36641 Number of extensions: 693814 Number of successful extensions: 1864 Number of sequences better than 10.0: 23 Number of HSP's better than 10.0 without gapping: 27 Number of HSP's successfully gapped in prelim test: 18 Number of HSP's that attempted gapping in prelim test: 1774 Number of HSP's gapped (non-prelim): 51 length of query: 480 length of database: 10,336,785 effective HSP length: 101 effective length of query: 379 effective length of database: 6,636,044 effective search space: 2515060676 effective search space used: 2515060676 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 61 (28.2 bits)