BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P10507 (462 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1HR8-B nrPDB 907 0.0 1BCC-A nrPDB 338 2e-93 5XTH-AL nrPDB 322 2e-88 6HAW-A nrPDB 319 1e-87 3L72-A nrPDB 304 6e-83 3HDI-A nrPDB 190 9e-49 6GIQ-A nrPDB 156 1e-38 1HR7-A nrPDB 154 9e-38 6HAW-B nrPDB 147 7e-36 2BCC-B nrPDB 142 4e-34 5GUP-v nrPDB 140 1e-33 5XTH-AK nrPDB 139 3e-33 3L73-B nrPDB 137 1e-32 3EOQ-A nrPDB 123 2e-28 5EUF-A nrPDB 82 7e-16 4NNZ-A nrPDB 74 2e-13 5CIO-A nrPDB 68 7e-12 1Q2L-A nrPDB 61 1e-09 3CX5-B nrPDB 59 7e-09 3GO9-A nrPDB 38 0.010 1SW7-A nrPDB 33 0.30 4POC-A nrPDB 32 0.81 2OWO-A nrPDB 30 3.0 4GLX-A nrPDB 29 3.7 4S3J-A nrPDB 28 7.8 4D6Y-A nrPDB 28 8.2 5M7N-A nrPDB 28 9.1 >1HR8-B nrPDB Length = 443 Score = 907 bits (2344), Expect = 0.0, Method: Compositional matrix adjust. Identities = 439/443 (99%), Positives = 442/443 (99%) Query: 20 SSQIPGTRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKG 79 +SQIPGTRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFL+HLAFKG Sbjct: 1 ASQIPGTRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLQHLAFKG 60 Query: 80 TQNRSQQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSA 139 TQNR QQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSA Sbjct: 61 TQNRPQQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSA 120 Query: 140 IERERDVIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYI 199 IERERDVIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYI Sbjct: 121 IERERDVIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYI 180 Query: 200 TKNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIK 259 TKNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIK Sbjct: 181 TKNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIK 240 Query: 260 ENTLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSL 319 ENTLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSL Sbjct: 241 ENTLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSL 300 Query: 320 ANSYMSFSTSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQ 379 ANSYMSFSTSYADSGLWGMYIVTDSNEHNV+LIVNEILKEWKRIKSGKISDAEVNRAKAQ Sbjct: 301 ANSYMSFSTSYADSGLWGMYIVTDSNEHNVRLIVNEILKEWKRIKSGKISDAEVNRAKAQ 360 Query: 380 LKAALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKPV 439 LKAALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKPV Sbjct: 361 LKAALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKPV 420 Query: 440 SMVALGNTSTVPNVSYIEEKLNQ 462 SMVALGNTSTVPNVSYIEEKLNQ Sbjct: 421 SMVALGNTSTVPNVSYIEEKLNQ 443 >1BCC-A nrPDB Length = 446 Score = 338 bits (868), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 174/402 (43%), Positives = 267/402 (66%), Gaps = 13/402 (3%) Query: 23 IPGTRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQN 82 +P T+ S+L NG+ +A+E + + TVG+++DAGSR E+ KNNG +FLEHLAFKGT+N Sbjct: 11 VPETQVSQLDNGVRVASEQ-SSQPTCTVGVWIDAGSRYESEKNNGAGYFLEHLAFKGTKN 69 Query: 83 RSQQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIER 142 R Q +E E+E++G+HLNAY+SRE+T YY K+L +D+PKAV++L+DI+ L++S IE+ Sbjct: 70 RPQNALEKEVESMGAHLNAYSSREHTAYYIKALSKDVPKAVELLADIVQNCSLEDSQIEK 129 Query: 143 ERDVIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKN 202 ERDVI+RE +E D EVVF++LH ++ L +++ GP +NI+ ++R DL +Y++ + Sbjct: 130 ERDVIVRELQENDTSMREVVFNYLHATAFQGTGLAQSVEGPSENIRKLSRADLTEYLSTH 189 Query: 203 YKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKS--ESPVP-LGSPRGPLPVFCRGERFIK 259 Y RMVLA AG V+H++L++ AQK+FG VP + + VP L R F + + Sbjct: 190 YTAPRMVLAAAGGVEHQQLLELAQKHFGGVPFTYDDDAVPTLSKCR-----FTGSQIRHR 244 Query: 260 ENTLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSL 319 E+ LP H+AIA+EG W+ PD AI+G++DR G G +S SPLA A N L Sbjct: 245 EDGLPLAHVAIAVEGPGWAHPDLVALQVANAIIGHYDRTYGGGLHSSSPLASIAVTN-KL 303 Query: 320 ANSYMSFSTSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQ 379 S+ +FS Y+++GL+G Y V D + + V + +W R+ + IS++EV R K Sbjct: 304 CQSFQTFSICYSETGLFGFYFVCDRMSIDDMMFV--LQGQWMRLCT-SISESEVLRGKNF 360 Query: 380 LKAALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKI 421 L+ AL+ LDG+T + EDIGR+++T G+R+ EE E++ ++ Sbjct: 361 LRNALVSHLDGTTPVCEDIGRELLTYGRRIPLEEWEERLAEV 402 >5XTH-AL nrPDB Length = 446 Score = 322 bits (825), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 164/392 (41%), Positives = 252/392 (64%), Gaps = 17/392 (4%) Query: 23 IPGTRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQN 82 +P T+ S L NGL +A+E + + TVG+++D GSR E KNNG +FLEHLAFKGT+N Sbjct: 11 VPETQVSLLDNGLRVASEQ-SSQPTCTVGVWIDVGSRFETEKNNGAGYFLEHLAFKGTKN 69 Query: 83 RSQQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIER 142 R +E E+E++G+HLNAY++RE+T YY K+L +D+PKAV++L DI+ L++S IE+ Sbjct: 70 RPGSALEKEVESMGAHLNAYSTREHTAYYIKALSKDLPKAVELLGDIVQNCSLEDSQIEK 129 Query: 143 ERDVIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKN 202 ERDVI+RE +E D +VVF++LH ++ PL + + GP +N++ ++R DL +Y++ + Sbjct: 130 ERDVILREMQENDASMRDVVFNYLHATAFQGTPLAQAVEGPSENVRKLSRADLTEYLSTH 189 Query: 203 YKGDRMVLAGAGAVDHEKLVQYAQKYFGHVP--KSESPVPLGSPRGPLPVFCR---GERF 257 YK RMVLA AG V+H++L+ AQK+ G +P +E VP +P CR E Sbjct: 190 YKAPRMVLAAAGGVEHQQLLDLAQKHLGGIPWTYAEDAVPTLTP-------CRFTGSEIR 242 Query: 258 IKENTLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNG 317 +++ LP H+AIA+EG W++PD AI+G++D G G + SPLA A N Sbjct: 243 HRDDALPFAHVAIAVEGPGWASPDNVALQVANAIIGHYDCTYGGGVHLSSPLASGAVAN- 301 Query: 318 SLANSYMSFSTSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAK 377 L S+ +FS YA++GL G + V D + + + V + +W R+ + +++EV R K Sbjct: 302 KLCQSFQTFSICYAETGLLGAHFVCDRMKIDDMMFV--LQGQWMRLCTSA-TESEVARGK 358 Query: 378 AQLKAALLLSLDGSTAIVEDIGRQVVTTGKRL 409 L+ AL+ LDG+T + EDIGR ++T G+R+ Sbjct: 359 NILRNALVSHLDGTTPVCEDIGRSLLTYGRRI 390 >6HAW-A nrPDB Length = 438 Score = 319 bits (818), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 163/390 (41%), Positives = 255/390 (65%), Gaps = 19/390 (4%) Query: 23 IPGTRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQN 82 +P T+ S+L NGL +A+E + + TVG+++DAGSR E+ KNNG +F+EHLAFKGT+N Sbjct: 10 VPETQVSQLDNGLRVASEQ-SSQPTCTVGVWIDAGSRYESEKNNGAGYFVEHLAFKGTKN 68 Query: 83 RSQQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIER 142 R +E E+E++G+HLNAY++RE+T YY K+L +D+PKAV++L+DI+ L++S IE+ Sbjct: 69 RPGNALEKEVESMGAHLNAYSTREHTAYYIKALSKDLPKAVELLADIVQNCSLEDSQIEK 128 Query: 143 ERDVIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKN 202 ERDVI++E +E D +VVF++LH ++ PL +++ GP +N++ ++R DL +Y++++ Sbjct: 129 ERDVILQELQENDTSMRDVVFNYLHATAFQGTPLAQSVEGPSENVRKLSRADLTEYLSRH 188 Query: 203 YKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCR--GERFI-K 259 YK RMVLA AG ++H +L+ AQK+F + S VP SP CR G + + Sbjct: 189 YKAPRMVLAAAGGLEHRQLLDLAQKHFSGL----SGVPTLSP-------CRFTGSQICHR 237 Query: 260 ENTLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSL 319 E+ LP H+AIA+EG W+ PD AI+G++D G G + SPLA A+ N L Sbjct: 238 EDGLPLAHVAIAVEGPGWAHPDNVALQVANAIIGHYDCTYGGGAHLSSPLASIAATN-KL 296 Query: 320 ANSYMSFSTSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQ 379 S+ +F+ YAD+GL G + V D + + V + +W R+ + +++EV R K Sbjct: 297 CQSFQTFNICYADTGLLGAHFVCDHMSIDDMMFV--LQGQWMRLCTSA-TESEVLRGKNL 353 Query: 380 LKAALLLSLDGSTAIVEDIGRQVVTTGKRL 409 L+ AL+ LDG+T + EDIGR ++T G+R+ Sbjct: 354 LRNALVSHLDGTTPVCEDIGRSLLTYGRRI 383 >3L72-A nrPDB Length = 446 Score = 304 bits (778), Expect = 6e-83, Method: Compositional matrix adjust. Identities = 158/393 (40%), Positives = 242/393 (61%), Gaps = 11/393 (2%) Query: 23 IPGTRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQN 82 IP T + L NGL +A+E + + TVG+++ AGSR EN KNNG +F+EHLAFKGT+ Sbjct: 11 IPETNVTTLDNGLRVASEE-SSQPTCTVGVWIGAGSRYENEKNNGAGYFVEHLAFKGTKK 69 Query: 83 RSQQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIER 142 R E E+E++G+H N YTSRE T +Y K+L +D+PK V++L+D++ L+ S IE+ Sbjct: 70 RPCAAFEKEVESMGAHFNGYTSREQTAFYIKALSKDMPKVVELLADVVQNCALEESQIEK 129 Query: 143 ERDVIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKN 202 ER VI++E +E+D V FD+LH ++ L RT+ G +NIK +TR DL YI + Sbjct: 130 ERGVILQELKEMDNDMTNVTFDYLHATAFQGTALARTVEGTTENIKHLTRADLASYIDTH 189 Query: 203 YKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKS--ESPVPLGSPRGPLPVFCRGERFIKE 260 +K RMVLA AG + H++LV A+++F V + E VP+ P F E ++ Sbjct: 190 FKAPRMVLAAAGGISHKELVDAARQHFSGVSFTYKEDAVPI----LPRCRFTGSEIRARD 245 Query: 261 NTLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSLA 320 + LP H+A+A+EG W+ PD V AI+G +DR G G + S LA A ++ L Sbjct: 246 DALPVAHVALAVEGPGWADPDNVVLHVANAIIGRYDRTFGGGKHLSSRLAALAVEH-KLC 304 Query: 321 NSYMSFSTSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQL 380 +S+ +F+TSY+D+GL+G + V D + + + EW R+ + +++EV RAK L Sbjct: 305 HSFQTFNTSYSDTGLFGFHFVADPLSIDDMMFCAQ--GEWMRLCT-STTESEVKRAKNHL 361 Query: 381 KAALLLSLDGSTAIVEDIGRQVVTTGKRLSPEE 413 ++A++ LDG+T + E IG ++ G+R+S EE Sbjct: 362 RSAMVAQLDGTTPVCETIGSHLLNYGRRISLEE 394 >3HDI-A nrPDB Length = 421 Score = 190 bits (483), Expect = 9e-49, Method: Compositional matrix adjust. Identities = 124/411 (30%), Positives = 207/411 (50%), Gaps = 18/411 (4%) Query: 28 TSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQG 87 T L NG+ I TE + S ++GI+V GSR E+ + NG +HFLEH+ FKGT RS Q Sbjct: 4 TMTLDNGVRIITEKMSTVRSVSIGIWVGTGSRYESAEENGISHFLEHMFFKGTNTRSAQE 63 Query: 88 IELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERDVI 147 I ++IG +NA+TS+E T YYAK L + +A+D LSD+ S +E+ER V+ Sbjct: 64 IAEFFDSIGGQVNAFTSKEYTCYYAKVLDDHAGQAIDTLSDMFFHSTFQKEELEKERKVV 123 Query: 148 IRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKNYKGDR 207 E + VD D++V D L TY LG ILG ++ + S L+ Y+ + Y GD Sbjct: 124 FEEIKMVDDTPDDIVHDLLSSATYGKHSLGYPILGTVETLNSFNEGMLRHYMDRFYTGDY 183 Query: 208 MVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIKENTLPTTH 267 +V++ AG V H++L+ ++ F V + + +G P+F R +++ H Sbjct: 184 VVISVAGNV-HDELIDKIKETFSQVKPTTY-----NYQGEKPMFLPN-RIVRKKETEQAH 236 Query: 268 IAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSLANSYMSFS 327 + + G+ D + + ++G G+ S S L + L S S+ Sbjct: 237 LCLGYPGLPIGDKDVYALVLLNNVLG--------GSMS-SRLFQDIREKRGLCYSVFSYH 287 Query: 328 TSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQLKAALLLS 387 +S+ DSG+ +Y T ++ + +V I + + +++ E+ K QLK +L+LS Sbjct: 288 SSFRDSGMLTIYAGTGHDQ--LDDLVYSIQETTSALAEKGLTEKELENGKEQLKGSLMLS 345 Query: 388 LDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKP 438 L+ + + + G+ + K S +E+ EQ++ + K D+ A L P Sbjct: 346 LESTNSRMSRNGKNELLLKKHRSLDEMIEQINAVQKQDVSRLAKILLSASP 396 >6GIQ-A nrPDB Length = 457 Score = 156 bits (395), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 119/443 (26%), Positives = 220/443 (49%), Gaps = 31/443 (6%) Query: 13 RRLLSTISSQIPGTRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFL 72 R L + +++ P ++L NG+ +ATE+ P+ +A+VG+ +G+ EN NNG ++ Sbjct: 16 RSLATAVAT--PKAEVTQLSNGIVVATEHNPSAHTASVGVVFGSGAANENPYNNGVSNLW 73 Query: 73 EHLAFKGTQNRSQQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTK 132 +++ F +N + E G L++ SR+ Y SL K++D L+ + Sbjct: 74 KNI-FLSKENSAVAAKE------GLALSSNISRDFQSYIVSSLPGSTDKSLDFLNQSFIQ 126 Query: 133 ---SVLDNSAIERERDVIIRESEEVDKM-YDEVVFDHLHEITYKDQPLGRTILGPIKNIK 188 ++L +S E + ++++ ++ ++ + V +HLH +++ PL G +++++ Sbjct: 127 QKANLLSSSNFEATKKSVLKQVQDFEENDHPNRVLEHLHSTAFQNTPLSLPTRGTLESLE 186 Query: 189 SITRTDLKDYITKNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPL 248 ++ DL+ + ++ V+ G G + HE LV + + PV Sbjct: 187 NLVVADLESFANNHFLNSNAVVVGTGNIKHEDLVNSIESKNLSLQTGTKPV-----LKKK 241 Query: 249 PVFCRGERFIKENTLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSP 308 F E ++++TLP I++A+EG ++P+YFVA I G+++ A + Sbjct: 242 AAFLGSEVRLRDDTLPKAWISLAVEGEPVNSPNYFVAKLAAQIFGSYN-AFEPASRLQGI 300 Query: 309 LAVAASQNGSLANSYMSFSTSYADSGLWGMYIVTDSNEHNVQLI---VNEILKEWKRIKS 365 + Q L +++ FS SY DSGLWG T NV +I ++ LK+W R+ + Sbjct: 301 KLLDNIQEYQLCDNFNHFSLSYKDSGLWGFSTAT----RNVTMIDDLIHFTLKQWNRL-T 355 Query: 366 GKISDAEVNRAKAQLKAALLLSLDGSTAIVED---IGRQVVTTGKRLSPEEVFEQVDKIT 422 ++D EV RAK+ LK L L S V D +G +V+ G +LS E F+++D IT Sbjct: 356 ISVTDTEVERAKSLLKLQ-LGQLYESGNPVNDANLLGAEVLIKGSKLSLGEAFKKIDAIT 414 Query: 423 KDDIIMWANYRLQNKPVSMVALG 445 D+ WA RL ++ +++ G Sbjct: 415 VKDVKAWAGKRLWDQDIAIAGTG 437 >1HR7-A nrPDB Length = 475 Score = 154 bits (388), Expect = 9e-38, Method: Compositional matrix adjust. Identities = 119/419 (28%), Positives = 201/419 (47%), Gaps = 37/419 (8%) Query: 27 RTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQ 86 + S L NGL +AT P SA +G+++DAGSR E G H L+ LAFK T++ + Sbjct: 7 KLSSLANGLKVATSNTPGHFSA-LGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEGR 65 Query: 87 GIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERDV 146 + +E +G + +SREN +Y A +D+ K + ++S+ + + ++ ++ Sbjct: 66 AMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKLS 125 Query: 147 IIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKNYKGD 206 E +EV + V+ + LH Y + LG ++ P I SI++ L DY K Y + Sbjct: 126 AEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRGLIPSISKYYLLDYRNKFYTPE 185 Query: 207 RMVLAGAGAVDHEKLVQYAQKYFG-----HVP---------KSESPVPLGSPRGPLPVFC 252 V A G V HEK ++ KY G H P ES +P P PVF Sbjct: 186 NTVAAFVG-VPHEKALELTGKYLGDWQSTHPPITKKVAQYTGGESCIP------PAPVF- 237 Query: 253 RGERFIKENTLPTT-HIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSP--SPL 309 LP HI I EG+ PD + Q ++G G S L Sbjct: 238 --------GNLPELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRL 289 Query: 310 AVAASQNGSLANSYMSFSTSYADSGLWGMYI--VTDSNEHNVQLIVNEILKEWKRIKSGK 367 + ++F+ SY+DSG++G+ + + + V++I ++ + K + Sbjct: 290 YTHVLNQYYFVENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFAN-KDLR 348 Query: 368 ISDAEVNRAKAQLKAALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDI 426 +++ EV+RAK QLK++LL++L+ +ED+GRQV+ G+++ E+ +++ + DDI Sbjct: 349 LTEDEVSRAKNQLKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDI 407 >6HAW-B nrPDB Length = 413 Score = 147 bits (372), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 120/437 (27%), Positives = 200/437 (45%), Gaps = 37/437 (8%) Query: 29 SKLPNGLTIAT--EYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQ 86 ++LPNGL IA+ Y P ++ +G+F+ AGSR EN N GT+H L + T+ S Sbjct: 6 TRLPNGLVIASLENYAP---ASRIGLFIKAGSRYENSNNLGTSHLLRLASSLTTKGASSF 62 Query: 87 GIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERDV 146 I IE +G L+ ++REN Y + L++D VDIL + L +V R Sbjct: 63 KITRGIEAVGGKLSVTSTRENMAYTVECLRDD----VDILMEFLL-NVTTAPEFRRWEVA 117 Query: 147 IIRESEEVDKMY-----DEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITK 201 ++ +DK V ++LH Y++ L ++ P I +T +L DY+ Sbjct: 118 ALQPQLRIDKAVALQNPQAHVIENLHAAAYRN-ALANSLYCPDYRIGKVTPVELHDYVQN 176 Query: 202 NYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIKEN 261 ++ RM L G G V H L Q A+++ + RG G ++N Sbjct: 177 HFTSARMALIGLG-VSHPVLKQVAEQFL-------------NIRGGAKAKYHGGEIREQN 222 Query: 262 TLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSLAN 321 H A+ E + + + Q ++G + G+N+ S L A ++ Sbjct: 223 GDSLVHAALVAESAAIGSAEANAFSVLQHVLGAGPH-VKRGSNATSSLYQAVAKGVHQPF 281 Query: 322 SYMSFSTSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQLK 381 +F+ SY+DSGL+G Y + S + ++ + K I G +S+ +V AK +LK Sbjct: 282 DVSAFNASYSDSGLFGFYTI--SQAASAGDVIKAAYNQVKTIAQGNLSNPDVQAAKNKLK 339 Query: 382 AALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKPVSM 441 A L+S++ S ++++G Q + G P V +Q+D + D+I A + + SM Sbjct: 340 AGYLMSVESSEGFLDEVGSQALAAGSYTPPSTVLQQIDAVADADVINAAKKFVSGRK-SM 398 Query: 442 VALGNTSTVPNVSYIEE 458 A GN P +I+E Sbjct: 399 AASGNLGHTP---FIDE 412 >2BCC-B nrPDB Length = 422 Score = 142 bits (357), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 120/438 (27%), Positives = 200/438 (45%), Gaps = 41/438 (9%) Query: 29 SKLPNGLTIAT--EYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQ 86 +KLPNGL IA+ Y P + T+G+F+ AGSR EN N GT+H L + T+ S Sbjct: 10 TKLPNGLVIASLENYSPGS---TIGVFIKAGSRYENSSNLGTSHLLRLASSLTTKGASSF 66 Query: 87 GIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERDV 146 I IE +G L+ ++REN Y + L++D+ ++ L ++ T R +V Sbjct: 67 KITRGIEAVGGKLSVESTRENMAYTVECLRDDVEILMEFLLNVTTAPEF------RPWEV 120 Query: 147 I-IRESEEVDKMY-----DEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYIT 200 ++ ++DK V ++LH Y++ L ++ P I +T +L D++ Sbjct: 121 ADLQPQLKIDKAVAFQNPQTHVIENLHAAAYRN-ALADSLYCPDYRIGKVTSVELHDFVQ 179 Query: 201 KNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFC-----RGE 255 ++ RM L G G V H L A++ L + RG L + RG Sbjct: 180 NHFTSARMALVGLG-VSHPVLKNVAEQ-------------LLNIRGGLGLSGAKAKYRGG 225 Query: 256 RFIKENTLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQ 315 ++N H AI E + + Q ++G + + G N+ S L A ++ Sbjct: 226 EIREQNGDSLVHAAIVAESAAIGGAEANAFSVLQHVLG-ANPHVKRGLNATSSLYQAVAK 284 Query: 316 NGSLANSYMSFSTSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNR 375 +F+ SY+DSGL+G Y ++ + ++ + K I G +S+ V Sbjct: 285 GVHQPFDVSAFNASYSDSGLFGFYTISQAAY--AGQVIKAAYNQVKTIAQGNVSNENVQA 342 Query: 376 AKAQLKAALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQ 435 AK +LKA L+S++ S +E++G Q + G P V +Q+D + D+I A + Sbjct: 343 AKNKLKAKYLMSVESSEGFLEEVGSQALAAGSYNPPSTVLQQIDAVADADVIKAAK-KFV 401 Query: 436 NKPVSMVALGNTSTVPNV 453 ++ SM A GN P V Sbjct: 402 SRQKSMAASGNLGHTPFV 419 >5GUP-v nrPDB Length = 453 Score = 140 bits (353), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 119/440 (27%), Positives = 204/440 (46%), Gaps = 45/440 (10%) Query: 29 SKLPNGLTIAT--EYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQ 86 ++LPNGL IA+ Y P ++ +G+F+ AGSR E+ N GT+H L + T+ S Sbjct: 41 TRLPNGLVIASLENYAP---ASRIGLFIKAGSRYEDSNNLGTSHLLRLASSLTTKGASSF 97 Query: 87 GIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERER-- 144 I IE +G L+ ++RE+ Y + L++DI +IL + +L+ +A R Sbjct: 98 KITRGIEAVGGKLSVTSTRESMAYTVECLRDDI--------EILMEFLLNVTAAPEFRRW 149 Query: 145 DVIIRESE-EVDKMY-----DEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDY 198 +V +S+ +DK V ++LH Y++ L ++ P I +T L Y Sbjct: 150 EVAALQSQLRIDKAVAFQNPQAQVLENLHAAAYRN-ALANSLYCPDYRIGKVTPDQLHYY 208 Query: 199 ITKNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFC-----R 253 + ++ RM L G G V H L Q A+++ + RG L + R Sbjct: 209 VQNHFTSARMALIGLG-VSHPVLKQVAERFL-------------NMRGGLGLSGAKAKYR 254 Query: 254 GERFIKENTLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAA 313 G +N H A+ E + + + Q ++G + G+N+ S L A Sbjct: 255 GGEIRDQNGDSLVHAALVAESAATGSAEANAFSVLQHVLGAGPH-VKRGSNATSSLYQAV 313 Query: 314 SQNGSLANSYMSFSTSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEV 373 ++ +F+ SY+DSGL+G+Y + S + ++ + K I G +S+ +V Sbjct: 314 AKGVHQPFDVSAFNASYSDSGLFGIYTI--SQAASAGDVIKSAYDQVKAIAQGNLSNTDV 371 Query: 374 NRAKAQLKAALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYR 433 AK +LKA L+S++ S ++++G Q + G + P V +Q+D + D+I A Sbjct: 372 QAAKNKLKAGYLMSVESSEGFLDEVGSQALVAGSYMQPSTVLQQIDSVADADVINAAKKF 431 Query: 434 LQNKPVSMVALGNTSTVPNV 453 + + SM A GN P V Sbjct: 432 VSGRK-SMAASGNLGHTPFV 450 >5XTH-AK nrPDB Length = 419 Score = 139 bits (349), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 120/436 (27%), Positives = 196/436 (44%), Gaps = 37/436 (8%) Query: 29 SKLPNGLTIATEYIPNTSSAT-VGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQG 87 +KLPNGL IA+ + N S + +G+F+ AGSR E+ N GT H L + T+ S Sbjct: 7 TKLPNGLVIAS--LENYSPVSRIGLFIKAGSRYEDFSNLGTTHLLRLTSSLTTKGASSFK 64 Query: 88 IELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERDVI 147 I IE +G L+ +REN Y + L+ D VDIL + L +V R Sbjct: 65 ITRGIEAVGGKLSVTATRENMAYTVECLRGD----VDILMEFLL-NVTTAPEFRRWEVAD 119 Query: 148 IRESEEVDKMY-----DEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKN 202 ++ ++DK V ++LH Y++ L + P I +T +L ++ + Sbjct: 120 LQPQLKIDKAVAFQNPQTHVIENLHAAAYRN-ALANPLYCPDYRIGKVTSEELHYFVQNH 178 Query: 203 YKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFC-----RGERF 257 + RM L G G V H L Q A+++ + RG L + RG Sbjct: 179 FTSARMALIGLG-VSHPVLKQVAEQFL-------------NMRGGLGLSGAKANYRGGEI 224 Query: 258 IKENTLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNG 317 ++N H A E + + Q ++G + G+N+ S L A ++ Sbjct: 225 REQNGDSLVHAAFVAESAVAGSAEANAFSVLQHVLGAGPH-VKRGSNTTSHLHQAVAKAT 283 Query: 318 SLANSYMSFSTSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAK 377 +F+ SY+DSGL+G+Y ++ + ++ + K I G +S+ +V AK Sbjct: 284 QQPFDVSAFNASYSDSGLFGIYTISQATAAGD--VIKAAYNQVKTIAQGNLSNTDVQAAK 341 Query: 378 AQLKAALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNK 437 +LKA L+S++ S +E++G Q + G + P V +Q+D + DII A + + Sbjct: 342 NKLKAGYLMSVESSECFLEEVGSQALVAGSYMPPSTVLQQIDSVANADIINAAKKFVSGQ 401 Query: 438 PVSMVALGNTSTVPNV 453 SM A GN P V Sbjct: 402 K-SMAASGNLGHTPFV 416 >3L73-B nrPDB Length = 441 Score = 137 bits (345), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 112/430 (26%), Positives = 197/430 (45%), Gaps = 29/430 (6%) Query: 29 SKLPNGLTIATEYIPNTSSAT-VGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQG 87 +KLPNGL IA+ + N S A+ +G+F+ AGSR E N GTAH L + T+ S Sbjct: 29 TKLPNGLIIAS--LENFSPASRIGVFIKAGSRYETTANLGTAHLLRLASPLTTKGASSFR 86 Query: 88 IELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTK------SVLDNSAIE 141 I IE +G L+ Y++RE Y + L++ + ++ L ++ T V D Sbjct: 87 ITRGIEAVGGSLSVYSTREKMTYCVECLRDHVDTVMEYLLNVTTAPEFRPWEVTDLQPQL 146 Query: 142 RERDVIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITK 201 + + +S +V V ++LH YK L + P I IT L ++ Sbjct: 147 KVDKAVAFQSPQVG------VLENLHAAAYKT-ALANPLYCPDYRIGKITSEQLHHFVQN 199 Query: 202 NYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIKEN 261 N+ RM L G G V H L Q A+++ + G+ G ++N Sbjct: 200 NFTSARMALVGIG-VKHSDLKQVAEQFLN--------IRSGAGTSSAKATYWGGEIREQN 250 Query: 262 TLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSLAN 321 H A+ EG + + + Q ++G I G++ S L ++ + Sbjct: 251 GHSLVHAAVVTEGAAVGSAEANAFSVLQHVLGAGPL-IKRGSSVTSKLYQGVAKATTQPF 309 Query: 322 SYMSFSTSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQLK 381 +F+ +Y+DSGL+G Y + S + ++ + + K G +++ +V +AK QLK Sbjct: 310 DASAFNVNYSDSGLFGFYTI--SQAAHAGEVIRAAMNQLKAAAQGGVTEEDVTKAKNQLK 367 Query: 382 AALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKPVSM 441 A L+S++ + ++ +IG + + +G +P V +++D +T D++ A + K SM Sbjct: 368 ATYLMSVETAQGLLNEIGSEALLSGTHTAPSVVAQKIDSVTSADVVNAAKKFVSGKK-SM 426 Query: 442 VALGNTSTVP 451 A G+ + P Sbjct: 427 AASGDLGSTP 436 >3EOQ-A nrPDB Length = 406 Score = 123 bits (309), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 111/406 (27%), Positives = 187/406 (46%), Gaps = 30/406 (7%) Query: 27 RTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQ 86 R ++L NGL + E +P S +G FV G+R E + +G +HFLEH+ FKG ++ Sbjct: 3 REAELRNGLRVIAEVVPGARSVALGYFVKTGARDETKEESGVSHFLEHMVFKGPEDMDAL 62 Query: 87 GIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERDV 146 + + +G+ NA+TS E TVYY L E + + + +L + L + E+ V Sbjct: 63 AVNRAFDRMGAQYNAFTSEEATVYYGAVLPEFAYDLLGLFAKLL-RPALREEDFQTEKLV 121 Query: 147 IIRESEEVDKMYDE---VVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKNY 203 I+ EE+ + D + ++ ++ PLG ++LG ++I ++TR + Y + Y Sbjct: 122 IL---EEIARYQDRPGFMAYEWARARFFQGHPLGNSVLGTRESITALTREGMAAYHRRRY 178 Query: 204 KGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPL-PVFCRGER-FIKEN 261 MVLA G VD ++L+ A++ P+ E+ PL P F ER + K Sbjct: 179 LPKNMVLAATGRVDFDRLLAEAERLTEAWPEGEAE----RAYPPLTPAFGVEERPYEKAR 234 Query: 262 TLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSLAN 321 L ++ GV++ F ++G G+G L A G LA Sbjct: 235 AL---YLVALFPGVAYQEEARFPGQVLAHLLGEE----GSGR-----LHFALVDKG-LAE 281 Query: 322 SYMSFSTSYAD-SGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQL 380 SF AD +G + Y+ D L V + +E R+ + + EV RAK L Sbjct: 282 V-ASFGLEEADRAGTFHAYVQADPARKGEVLAV--LQEELDRLGREGVGEEEVERAKTPL 338 Query: 381 KAALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDI 426 L+ + + + +G + + TG+ LS EEV +V ++T ++ Sbjct: 339 ATGLVFAGETPMQRLFHLGMEYLYTGRYLSLEEVKARVQRVTSREV 384 >5EUF-A nrPDB Length = 419 Score = 81.6 bits (200), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 88/380 (23%), Positives = 165/380 (43%), Gaps = 24/380 (6%) Query: 23 IPGTRTSKLPNGLTIATEYIPN-TSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQ 81 +P + L NGL + + + N T V + GSR E + +G AH LEHL FK T+ Sbjct: 5 LPKHESVTLKNGLQVVSVPLENKTGVIEVDVLYKVGSRNEVMGKSGIAHMLEHLNFKSTK 64 Query: 82 NRSQQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIE 141 N + ++ G NA TS + T Y+ K+ + ++ K++++ ++ + L Sbjct: 65 NLKAGEFDKIVKRFGGVSNASTSFDITRYFIKTSEANLDKSLELFAETMGSLNLKEDEFL 124 Query: 142 RERDVIIRESE-EVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYIT 200 ER V+ E D +++ Y P T +G + +I++ T D+K + + Sbjct: 125 PERQVVAEERRWRTDNSPIGMLYFRFFNTAYVYHPYHWTPIGFMDDIQNWTLKDIKKFHS 184 Query: 201 KNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIKE 260 Y+ ++ G V+ +K+ + +K+F ES L P P ++KE Sbjct: 185 LYYQPKNAIVLVVGDVNSQKVFELTKKHF------ESLKNLDEKAIPTP-------YMKE 231 Query: 261 NTLPTTHIAIA-LEGV--SWSAPDYFVAL---ATQAIVGNWDRAIGTGTNSPSPLAVAAS 314 A+ +GV W A Y V Q + + +G G + S L Sbjct: 232 PKQDGARTAVVHKDGVHLEWVALGYKVPAFKHKDQVALDALSKLLGEGKS--SWLQSELV 289 Query: 315 QNGSLANSYMSFSTSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVN 374 LA+ S + D ++ ++I + + + EI+ +++K G+I+ AE++ Sbjct: 290 DKKRLASQAFSHNMQLQDESVF-LFIAGGNPNIKAEALQKEIVALLEKLKKGEITQAELD 348 Query: 375 RAKAQLKAALLLSLDGSTAI 394 + K KA + +L+ S+ + Sbjct: 349 KIKINQKADFISNLESSSDV 368 >4NNZ-A nrPDB Length = 439 Score = 73.6 bits (179), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 92/413 (22%), Positives = 167/413 (40%), Gaps = 29/413 (7%) Query: 26 TRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQ 85 T L NGL + ++ GS E G +H LEH+ FKG++ Sbjct: 7 THEFSLDNGLKVIVREDHRAPVVVSQLWYRIGSSYETPGLTGLSHALEHMMFKGSRKLGP 66 Query: 86 QGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERD 145 + ++G+ NA+T+ + T YY ++ +P A+++ +D + L + E + Sbjct: 67 GEASRVLRDLGAEENAFTTDDYTAYYQVLARDRLPVALEMEADRMAHLSLPVDQFKSEIE 126 Query: 146 VIIRESE-EVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKNYK 204 VI E D + + F+ Y +G + +++ +T DL+ + Y Sbjct: 127 VIKEERRLRTDDNPNALAFERFKAAAYPASGYHTPTIGWMADLQRMTIDDLRHWYESWYA 186 Query: 205 GDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIK---EN 261 + L G V +++ A++YFG +P + P R PL + GER +K Sbjct: 187 PNNATLVVVGDVTADEVKTLAKRYFGEIPWRQLP----PARKPLELAEPGERRLKLYVRT 242 Query: 262 TLPTTHIAIALEGVSWSA-PDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSLA 320 LP + + + S P AL R IG + +A+ Sbjct: 243 QLPNLIMGFNVPSLGSSENPREVNAL----------RLIGALLDGGYSARLASRLER--G 290 Query: 321 NSYMSFSTSYADSGLWGMYIVTDSNEHNVQ------LIVNEILKEWKRIKSGKISDAEVN 374 ++ +++Y D+ G + S NVQ + + K+ +K S AE+ Sbjct: 291 EELVAGASTYYDAFNRGDSLFVLSATPNVQKGKTLEQVEAGLWKQLDDLKQNPPSAAEIE 350 Query: 375 RAKAQLKAALLLSLDGSTAIVEDIGR-QVVTTGKRLSPEEVFEQVDKITKDDI 426 R +AQ+ A ++ D A IG+ + V +L +++ E + +T DDI Sbjct: 351 RVRAQMIAGMVYEKDSIAAQASSIGQLESVGLSWKLIDQDL-EALKAVTPDDI 402 >5CIO-A nrPDB Length = 793 Score = 68.2 bits (165), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 60/224 (26%), Positives = 95/224 (42%), Gaps = 22/224 (9%) Query: 30 KLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRS-QQGI 88 +L NGL + P +A + ++AGS G AH LEH+ F+G+ N S Q G+ Sbjct: 31 QLDNGLAVRAISTPGAEAAAALVRIEAGSFQAPAAWPGLAHLLEHMLFRGSANFSAQDGL 90 Query: 89 ELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERDVI- 147 + G LNA T T ++ + + + + + LSD+L L AI +E +VI Sbjct: 91 MGWTQAAGGRLNATTQATQTAFFFEVGADPLAEGLARLSDMLAAPQLAAEAIAQEIEVID 150 Query: 148 -----IRESEEV------DKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLK 196 +R E +M+ FD LH R G +I ++ + L+ Sbjct: 151 AEYRLLRADGETRCEAAQRQMFSG--FDALHRFHIGS----RAAFG--SDISALQQA-LR 201 Query: 197 DYITKNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVP 240 + Y+ M L G E+L AQ+Y G +P + P Sbjct: 202 QFHHHYYRAPNMTLWLQGPQSLEQLHALAQRYGGGLPSGSATPP 245 >1Q2L-A nrPDB Length = 939 Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 57/220 (25%), Positives = 94/220 (42%), Gaps = 13/220 (5%) Query: 30 KLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQGIE 89 +L NG+ + P + + V GS + G AH+LEH++ G++ Q Sbjct: 25 RLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQADSL 84 Query: 90 LEIENI--GSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERDVI 147 E + GSH NA T+ T +Y + + +P AVD L+D + + +LD ERER+ + Sbjct: 85 AEYLKMHGGSH-NASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERNAV 143 Query: 148 IRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSIT-------RTDLKDYIT 200 E + + D + + T G G N+++++ + LKD+ Sbjct: 144 NAEL-TMARTRDGMRMAQVSAETINPAHPGSKFSG--GNLETLSDKPGNPVQQALKDFHE 200 Query: 201 KNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVP 240 K Y + M +L + A FG VP ES P Sbjct: 201 KYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKP 240 >3CX5-B nrPDB Length = 352 Score = 58.5 bits (140), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 84/365 (23%), Positives = 147/365 (40%), Gaps = 77/365 (21%) Query: 35 LTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQGIELEIEN 94 LT++ P T +T+ + V GSR +G AH L F+ T RS + E E Sbjct: 1 LTVSARDAP-TKISTLAVKVHGGSRYAT--KDGVAHLLNRFNFQNTNTRSALKLVRESEL 57 Query: 95 IGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSV-----LDNSAIERER-DVII 148 +G + RE A L++D+P V+ L+D+L K+ L S + R D + Sbjct: 58 LGGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAV 117 Query: 149 RESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKNYKGDRM 208 E V D+ L+ IT++ + LG +L ++ ++ D+KD+ K Y + + Sbjct: 118 AEQCPVKSAEDQ-----LYAITFR-KGLGNPLL--YDGVERVSLQDIKDFADKVYTKENL 169 Query: 209 VLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIKENTLPTTHI 268 ++G V+ + +RF+ E+ L T Sbjct: 170 EVSGENVVEADL----------------------------------KRFVDESLLSTLPA 195 Query: 269 AIALEGVSWSAPDYFVALATQA-IVGNWDRAIGTGTNSPSPLAVAASQNGSLANSYMSFS 327 +L VS S P +F+ + +G+ AIG N S +Q LAN Y++ + Sbjct: 196 GKSL--VSKSEPKFFLGEENRVRFIGDSVAAIGIPVNKAS-----LAQYEVLAN-YLTSA 247 Query: 328 TS-------------YADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVN 374 S + D GL+ +++ + + ++ + I K +K GK +N Sbjct: 248 LSELSGLISSAKLDKFTDGGLFTLFV----RDQDSAVVSSNIKKIVADLKKGKDLSPAIN 303 Query: 375 RAKAQ 379 K + Sbjct: 304 YTKLK 308 >3GO9-A nrPDB Length = 492 Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust. Identities = 63/253 (24%), Positives = 101/253 (39%), Gaps = 33/253 (13%) Query: 24 PGTRTSKLPNGLTIATEYIPNTSSATVGI--FVDAGSRAENVKNNGTAHFLEHLAFKGT- 80 P + KL NG + P S + + V+ GS +EN + G AH L LA + Sbjct: 24 PAWQQGKLDNGFSWQLLATPQRPSDRIELRLIVNTGSLSENTQEVGFAHLLPRLALMSSA 83 Query: 81 -------QNRSQQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILT-- 131 Q+ QQG I+N A TS + T+ Y+ SL + P D+L D L Sbjct: 84 SFTPAQLQSLWQQG----IDNERPLPPAITSYDFTL-YSLSLPNNRP---DLLKDALAWL 135 Query: 132 KSVLDNSAIERERDVIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILG-----PIKN 186 N A+ E+ V + D + ++ E ++ + G +++G P+ Sbjct: 136 SDTAGNLAVS-EQTVNAALNTATDPI--ATFPQNIQEPWWRYRLKGSSLIGHDPGQPVTQ 192 Query: 187 IKSITRTDLKDYITKNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVP-KSESPVPLG--S 243 + + LK + + Y D M L G VD + K F + K +P + + Sbjct: 193 PVDVEK--LKQFYQQWYTPDAMTLYVVGNVDSRSIAAQISKAFSELKGKRTAPAAVATLA 250 Query: 244 PRGPLPVFCRGER 256 P P PV E+ Sbjct: 251 PLPPEPVSLMNEQ 263 >1SW7-A nrPDB Length = 248 Score = 32.7 bits (73), Expect = 0.30, Method: Compositional matrix adjust. Identities = 23/75 (30%), Positives = 35/75 (46%), Gaps = 9/75 (12%) Query: 393 AIVEDIGRQVVTTGKRLSPEE-------VFEQVDKITKDDIIMWANYRLQNKPVSMVALG 445 A+ E +G + G++L E VFEQ I D++ W+ L +PV + G Sbjct: 116 ALAEGLGV-IACIGEKLDEREAGITEKVVFEQTKAIA-DNVKDWSKVVLAYEPVWAIGTG 173 Query: 446 NTSTVPNVSYIEEKL 460 N+ST + EKL Sbjct: 174 NSSTPQQAQEVHEKL 188 >4POC-A nrPDB Length = 254 Score = 31.6 bits (70), Expect = 0.81, Method: Compositional matrix adjust. Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 9/75 (12%) Query: 393 AIVEDIGRQVVTTGKRLSPEE-------VFEQVDKITKDDIIMWANYRLQNKPVSMVALG 445 A+ E +G + G++L E VFEQ K+ D++ W+ L +PV + G Sbjct: 122 ALAEGLGV-IACIGEKLDEREAGITEKVVFEQT-KVIADNVKDWSKVVLAYEPVWAIGTG 179 Query: 446 NTSTVPNVSYIEEKL 460 T+T + EKL Sbjct: 180 KTATPQQAQEVHEKL 194 >2OWO-A nrPDB Length = 671 Score = 29.6 bits (65), Expect = 3.0, Method: Compositional matrix adjust. Identities = 13/41 (31%), Positives = 19/41 (46%) Query: 240 PLGSPRGPLPVFCRGERFIKENTLPTTHIAIALEGVSWSAP 280 P + + PL FC G ++ LP TH+ L+ W P Sbjct: 212 PRITAKRPLTFFCYGVGVLEGGELPDTHLGRLLQFKKWGLP 252 >4GLX-A nrPDB Length = 586 Score = 29.3 bits (64), Expect = 3.7, Method: Compositional matrix adjust. Identities = 13/41 (31%), Positives = 19/41 (46%) Query: 240 PLGSPRGPLPVFCRGERFIKENTLPTTHIAIALEGVSWSAP 280 P + + PL FC G ++ LP TH+ L+ W P Sbjct: 212 PRITAKRPLTFFCYGVGVLEGGELPDTHLGRLLQFKKWGLP 252 >4S3J-A nrPDB Length = 433 Score = 28.1 bits (61), Expect = 7.8, Method: Compositional matrix adjust. Identities = 12/27 (44%), Positives = 18/27 (66%) Query: 30 KLPNGLTIATEYIPNTSSATVGIFVDA 56 +LP+G T++T +P TSS G F +A Sbjct: 240 RLPSGYTLSTTLVPKTSSNQKGKFFEA 266 >4D6Y-A nrPDB Length = 148 Score = 28.1 bits (61), Expect = 8.2, Method: Composition-based stats. Identities = 14/40 (35%), Positives = 21/40 (52%) Query: 182 GPIKNIKSITRTDLKDYITKNYKGDRMVLAGAGAVDHEKL 221 G I+ S R D+I K +K DR++L A++ KL Sbjct: 100 GNIETAVSAIRRGAYDFIEKPFKADRLILVAERALETSKL 139 >5M7N-A nrPDB Length = 454 Score = 28.1 bits (61), Expect = 9.1, Method: Compositional matrix adjust. Identities = 14/40 (35%), Positives = 21/40 (52%) Query: 182 GPIKNIKSITRTDLKDYITKNYKGDRMVLAGAGAVDHEKL 221 G I+ S R D+I K +K DR++L A++ KL Sbjct: 87 GNIETAVSAIRRGAYDFIEKPFKADRLILVAERALETSKL 126 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1HR8-B nrPDB 574 e-164 1BCC-A nrPDB 485 e-137 5XTH-AL nrPDB 471 e-133 6HAW-A nrPDB 471 e-133 3L72-A nrPDB 460 e-130 6HAW-B nrPDB 415 e-116 5GUP-v nrPDB 408 e-114 5XTH-AK nrPDB 406 e-114 2BCC-B nrPDB 401 e-112 3L73-B nrPDB 386 e-107 3HDI-A nrPDB 386 e-107 6GIQ-A nrPDB 354 3e-98 1HR7-A nrPDB 354 3e-98 4NNZ-A nrPDB 328 3e-90 3EOQ-A nrPDB 302 2e-82 5EUF-A nrPDB 298 3e-81 1Q2L-A nrPDB 183 2e-46 5CIO-A nrPDB 177 1e-44 3CX5-B nrPDB 168 3e-42 Sequences not found previously or not previously below threshold: 3GO9-A nrPDB 84 1e-16 2FGE-A nrPDB 80 3e-15 5XL8-A nrPDB 37 0.023 6GCS-A nrPDB 34 0.13 5UBV-A nrPDB 32 0.52 1SW7-A nrPDB 32 0.56 3PDI-A nrPDB 31 0.93 5XW0-A nrPDB 31 1.1 5A79-A nrPDB 31 1.4 1TA3-B nrPDB 28 9.2 >1HR8-B nrPDB Length = 443 Score = 574 bits (1480), Expect = e-164, Method: Composition-based stats. Identities = 439/443 (99%), Positives = 442/443 (99%) Query: 20 SSQIPGTRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKG 79 +SQIPGTRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFL+HLAFKG Sbjct: 1 ASQIPGTRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLQHLAFKG 60 Query: 80 TQNRSQQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSA 139 TQNR QQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSA Sbjct: 61 TQNRPQQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSA 120 Query: 140 IERERDVIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYI 199 IERERDVIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYI Sbjct: 121 IERERDVIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYI 180 Query: 200 TKNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIK 259 TKNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIK Sbjct: 181 TKNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIK 240 Query: 260 ENTLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSL 319 ENTLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSL Sbjct: 241 ENTLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSL 300 Query: 320 ANSYMSFSTSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQ 379 ANSYMSFSTSYADSGLWGMYIVTDSNEHNV+LIVNEILKEWKRIKSGKISDAEVNRAKAQ Sbjct: 301 ANSYMSFSTSYADSGLWGMYIVTDSNEHNVRLIVNEILKEWKRIKSGKISDAEVNRAKAQ 360 Query: 380 LKAALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKPV 439 LKAALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKPV Sbjct: 361 LKAALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKPV 420 Query: 440 SMVALGNTSTVPNVSYIEEKLNQ 462 SMVALGNTSTVPNVSYIEEKLNQ Sbjct: 421 SMVALGNTSTVPNVSYIEEKLNQ 443 >1BCC-A nrPDB Length = 446 Score = 485 bits (1249), Expect = e-137, Method: Composition-based stats. Identities = 174/435 (40%), Positives = 277/435 (63%), Gaps = 7/435 (1%) Query: 22 QIPGTRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQ 81 +P T+ S+L NG+ +A+E + + TVG+++DAGSR E+ KNNG +FLEHLAFKGT+ Sbjct: 10 SVPETQVSQLDNGVRVASEQ-SSQPTCTVGVWIDAGSRYESEKNNGAGYFLEHLAFKGTK 68 Query: 82 NRSQQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIE 141 NR Q +E E+E++G+HLNAY+SRE+T YY K+L +D+PKAV++L+DI+ L++S IE Sbjct: 69 NRPQNALEKEVESMGAHLNAYSSREHTAYYIKALSKDVPKAVELLADIVQNCSLEDSQIE 128 Query: 142 RERDVIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITK 201 +ERDVI+RE +E D EVVF++LH ++ L +++ GP +NI+ ++R DL +Y++ Sbjct: 129 KERDVIVRELQENDTSMREVVFNYLHATAFQGTGLAQSVEGPSENIRKLSRADLTEYLST 188 Query: 202 NYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIKEN 261 +Y RMVLA AG V+H++L++ AQK+FG VP + + P F + +E+ Sbjct: 189 HYTAPRMVLAAAGGVEHQQLLELAQKHFGGVPFTYDDDAV--PTLSKCRFTGSQIRHRED 246 Query: 262 TLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSLAN 321 LP H+AIA+EG W+ PD AI+G++DR G G +S SPLA A N L Sbjct: 247 GLPLAHVAIAVEGPGWAHPDLVALQVANAIIGHYDRTYGGGLHSSSPLASIAVTN-KLCQ 305 Query: 322 SYMSFSTSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQLK 381 S+ +FS Y+++GL+G Y V D + + V + +W R+ + IS++EV R K L+ Sbjct: 306 SFQTFSICYSETGLFGFYFVCDRMSIDDMMFV--LQGQWMRLCT-SISESEVLRGKNFLR 362 Query: 382 AALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKPVSM 441 AL+ LDG+T + EDIGR+++T G+R+ EE E++ ++ + + + ++ ++ Sbjct: 363 NALVSHLDGTTPVCEDIGRELLTYGRRIPLEEWEERLAEVDARMVREVCSKYIYDQCPAV 422 Query: 442 VALGNTSTVPNVSYI 456 G +P+ + I Sbjct: 423 AGPGPIEQLPDYNRI 437 >5XTH-AL nrPDB Length = 446 Score = 471 bits (1212), Expect = e-133, Method: Composition-based stats. Identities = 167/436 (38%), Positives = 269/436 (61%), Gaps = 11/436 (2%) Query: 23 IPGTRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQN 82 +P T+ S L NGL +A+E + + TVG+++D GSR E KNNG +FLEHLAFKGT+N Sbjct: 11 VPETQVSLLDNGLRVASEQ-SSQPTCTVGVWIDVGSRFETEKNNGAGYFLEHLAFKGTKN 69 Query: 83 RSQQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIER 142 R +E E+E++G+HLNAY++RE+T YY K+L +D+PKAV++L DI+ L++S IE+ Sbjct: 70 RPGSALEKEVESMGAHLNAYSTREHTAYYIKALSKDLPKAVELLGDIVQNCSLEDSQIEK 129 Query: 143 ERDVIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKN 202 ERDVI+RE +E D +VVF++LH ++ PL + + GP +N++ ++R DL +Y++ + Sbjct: 130 ERDVILREMQENDASMRDVVFNYLHATAFQGTPLAQAVEGPSENVRKLSRADLTEYLSTH 189 Query: 203 YKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKS--ESPVPLGSPRGPLPVFCRGERFIKE 260 YK RMVLA AG V+H++L+ AQK+ G +P + E VP +P F E ++ Sbjct: 190 YKAPRMVLAAAGGVEHQQLLDLAQKHLGGIPWTYAEDAVPTLTP----CRFTGSEIRHRD 245 Query: 261 NTLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSLA 320 + LP H+AIA+EG W++PD AI+G++D G G + SPLA A N L Sbjct: 246 DALPFAHVAIAVEGPGWASPDNVALQVANAIIGHYDCTYGGGVHLSSPLASGAVAN-KLC 304 Query: 321 NSYMSFSTSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQL 380 S+ +FS YA++GL G + V D + + + V + +W R+ + +++EV R K L Sbjct: 305 QSFQTFSICYAETGLLGAHFVCDRMKIDDMMFV--LQGQWMRLCTSA-TESEVARGKNIL 361 Query: 381 KAALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKPVS 440 + AL+ LDG+T + EDIGR ++T G+R+ E ++ ++ + + + ++ + Sbjct: 362 RNALVSHLDGTTPVCEDIGRSLLTYGRRIPLAEWESRIAEVDASVVREICSKYIYDQCPA 421 Query: 441 MVALGNTSTVPNVSYI 456 + G +P+ + I Sbjct: 422 VAGYGPIEQLPDYNRI 437 >6HAW-A nrPDB Length = 438 Score = 471 bits (1211), Expect = e-133, Method: Composition-based stats. Identities = 165/435 (37%), Positives = 270/435 (62%), Gaps = 13/435 (2%) Query: 22 QIPGTRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQ 81 +P T+ S+L NGL +A+E + + TVG+++DAGSR E+ KNNG +F+EHLAFKGT+ Sbjct: 9 SVPETQVSQLDNGLRVASEQ-SSQPTCTVGVWIDAGSRYESEKNNGAGYFVEHLAFKGTK 67 Query: 82 NRSQQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIE 141 NR +E E+E++G+HLNAY++RE+T YY K+L +D+PKAV++L+DI+ L++S IE Sbjct: 68 NRPGNALEKEVESMGAHLNAYSTREHTAYYIKALSKDLPKAVELLADIVQNCSLEDSQIE 127 Query: 142 RERDVIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITK 201 +ERDVI++E +E D +VVF++LH ++ PL +++ GP +N++ ++R DL +Y+++ Sbjct: 128 KERDVILQELQENDTSMRDVVFNYLHATAFQGTPLAQSVEGPSENVRKLSRADLTEYLSR 187 Query: 202 NYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIKEN 261 +YK RMVLA AG ++H +L+ AQK+F + S VP SP F + +E+ Sbjct: 188 HYKAPRMVLAAAGGLEHRQLLDLAQKHFSGL----SGVPTLSP----CRFTGSQICHRED 239 Query: 262 TLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSLAN 321 LP H+AIA+EG W+ PD AI+G++D G G + SPLA A+ N L Sbjct: 240 GLPLAHVAIAVEGPGWAHPDNVALQVANAIIGHYDCTYGGGAHLSSPLASIAATN-KLCQ 298 Query: 322 SYMSFSTSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQLK 381 S+ +F+ YAD+GL G + V D + + V + +W R+ + +++EV R K L+ Sbjct: 299 SFQTFNICYADTGLLGAHFVCDHMSIDDMMFV--LQGQWMRLCTSA-TESEVLRGKNLLR 355 Query: 382 AALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKPVSM 441 AL+ LDG+T + EDIGR ++T G+R+ E ++ ++ + + ++ ++ Sbjct: 356 NALVSHLDGTTPVCEDIGRSLLTYGRRIPLAEWESRIAEVDARVVREVCSKYFYDQCPAV 415 Query: 442 VALGNTSTVPNVSYI 456 G +P+ + I Sbjct: 416 AGFGPIEQLPDYNRI 430 >3L72-A nrPDB Length = 446 Score = 460 bits (1183), Expect = e-130, Method: Composition-based stats. Identities = 161/426 (37%), Positives = 254/426 (59%), Gaps = 11/426 (2%) Query: 22 QIPGTRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQ 81 IP T + L NGL +A+E + + TVG+++ AGSR EN KNNG +F+EHLAFKGT+ Sbjct: 10 NIPETNVTTLDNGLRVASEE-SSQPTCTVGVWIGAGSRYENEKNNGAGYFVEHLAFKGTK 68 Query: 82 NRSQQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIE 141 R E E+E++G+H N YTSRE T +Y K+L +D+PK V++L+D++ L+ S IE Sbjct: 69 KRPCAAFEKEVESMGAHFNGYTSREQTAFYIKALSKDMPKVVELLADVVQNCALEESQIE 128 Query: 142 RERDVIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITK 201 +ER VI++E +E+D V FD+LH ++ L RT+ G +NIK +TR DL YI Sbjct: 129 KERGVILQELKEMDNDMTNVTFDYLHATAFQGTALARTVEGTTENIKHLTRADLASYIDT 188 Query: 202 NYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKS--ESPVPLGSPRGPLPVFCRGERFIK 259 ++K RMVLA AG + H++LV A+++F V + E VP+ P F E + Sbjct: 189 HFKAPRMVLAAAGGISHKELVDAARQHFSGVSFTYKEDAVPIL----PRCRFTGSEIRAR 244 Query: 260 ENTLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSL 319 ++ LP H+A+A+EG W+ PD V AI+G +DR G G + S LA A ++ L Sbjct: 245 DDALPVAHVALAVEGPGWADPDNVVLHVANAIIGRYDRTFGGGKHLSSRLAALAVEH-KL 303 Query: 320 ANSYMSFSTSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQ 379 +S+ +F+TSY+D+GL+G + V D + + EW R+ + +++EV RAK Sbjct: 304 CHSFQTFNTSYSDTGLFGFHFVADPLSIDDMMFC--AQGEWMRLCT-STTESEVKRAKNH 360 Query: 380 LKAALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKPV 439 L++A++ LDG+T + E IG ++ G+R+S EE ++ + + + + +K Sbjct: 361 LRSAMVAQLDGTTPVCETIGSHLLNYGRRISLEEWDSRISAVDARMVRDVCSKYIYDKCP 420 Query: 440 SMVALG 445 ++ A+G Sbjct: 421 ALAAVG 426 >6HAW-B nrPDB Length = 413 Score = 415 bits (1067), Expect = e-116, Method: Composition-based stats. Identities = 111/432 (25%), Positives = 194/432 (44%), Gaps = 30/432 (6%) Query: 27 RTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQ 86 ++LPNGL IA+ ++ +G+F+ AGSR EN N GT+H L + T+ S Sbjct: 4 EFTRLPNGLVIASLEN-YAPASRIGLFIKAGSRYENSNNLGTSHLLRLASSLTTKGASSF 62 Query: 87 GIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERDV 146 I IE +G L+ ++REN Y + L++D+ ++ L ++ T R Sbjct: 63 KITRGIEAVGGKLSVTSTRENMAYTVECLRDDVDILMEFLLNVTTAP-----EFRRWEVA 117 Query: 147 IIRESEEVDK-----MYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITK 201 ++ +DK V ++LH Y++ L ++ P I +T +L DY+ Sbjct: 118 ALQPQLRIDKAVALQNPQAHVIENLHAAAYRN-ALANSLYCPDYRIGKVTPVELHDYVQN 176 Query: 202 NYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIKEN 261 ++ RM L G G V H L Q A+++ + RG G ++N Sbjct: 177 HFTSARMALIGLG-VSHPVLKQVAEQFL-------------NIRGGAKAKYHGGEIREQN 222 Query: 262 TLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSLAN 321 H A+ E + + + Q ++G + G+N+ S L A ++ Sbjct: 223 GDSLVHAALVAESAAIGSAEANAFSVLQHVLGAGPH-VKRGSNATSSLYQAVAKGVHQPF 281 Query: 322 SYMSFSTSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQLK 381 +F+ SY+DSGL+G Y ++ + ++ + K I G +S+ +V AK +LK Sbjct: 282 DVSAFNASYSDSGLFGFYTISQAAS--AGDVIKAAYNQVKTIAQGNLSNPDVQAAKNKLK 339 Query: 382 AALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKPVSM 441 A L+S++ S ++++G Q + G P V +Q+D + D+I A + + SM Sbjct: 340 AGYLMSVESSEGFLDEVGSQALAAGSYTPPSTVLQQIDAVADADVINAAKKFVSGRK-SM 398 Query: 442 VALGNTSTVPNV 453 A GN P + Sbjct: 399 AASGNLGHTPFI 410 >5GUP-v nrPDB Length = 453 Score = 408 bits (1047), Expect = e-114, Method: Composition-based stats. Identities = 116/461 (25%), Positives = 202/461 (43%), Gaps = 29/461 (6%) Query: 2 FSRTASKFRNTRRLLSTISSQIP----GTRTSKLPNGLTIATEYIPNTSSATVGIFVDAG 57 FSR S + L S + +P ++LPNGL IA+ ++ +G+F+ AG Sbjct: 10 FSRFYSLKVAPKALASAAPAGVPLQPQDLEFTRLPNGLVIASLEN-YAPASRIGLFIKAG 68 Query: 58 SRAENVKNNGTAHFLEHLAFKGTQNRSQQGIELEIENIGSHLNAYTSRENTVYYAKSLQE 117 SR E+ N GT+H L + T+ S I IE +G L+ ++RE+ Y + L++ Sbjct: 69 SRYEDSNNLGTSHLLRLASSLTTKGASSFKITRGIEAVGGKLSVTSTRESMAYTVECLRD 128 Query: 118 DIPKAVDILSDILTKSVLDNSAIERERDVIIRESEEVDK-----MYDEVVFDHLHEITYK 172 DI ++ L ++ R ++ +DK V ++LH Y+ Sbjct: 129 DIEILMEFLLNVTAAP-----EFRRWEVAALQSQLRIDKAVAFQNPQAQVLENLHAAAYR 183 Query: 173 DQPLGRTILGPIKNIKSITRTDLKDYITKNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHV 232 + L ++ P I +T L Y+ ++ RM L G G V H L Q A+++ Sbjct: 184 N-ALANSLYCPDYRIGKVTPDQLHYYVQNHFTSARMALIGLG-VSHPVLKQVAERFLN-- 239 Query: 233 PKSESPVPLGSPRGPLPVFCRGERFIKENTLPTTHIAIALEGVSWSAPDYFVALATQAIV 292 + G RG +N H A+ E + + + Q ++ Sbjct: 240 ------MRGGLGLSGAKAKYRGGEIRDQNGDSLVHAALVAESAATGSAEANAFSVLQHVL 293 Query: 293 GNWDRAIGTGTNSPSPLAVAASQNGSLANSYMSFSTSYADSGLWGMYIVTDSNEHNVQLI 352 G + G+N+ S L A ++ +F+ SY+DSGL+G+Y ++ + + Sbjct: 294 GAGPH-VKRGSNATSSLYQAVAKGVHQPFDVSAFNASYSDSGLFGIYTISQAAS--AGDV 350 Query: 353 VNEILKEWKRIKSGKISDAEVNRAKAQLKAALLLSLDGSTAIVEDIGRQVVTTGKRLSPE 412 + + K I G +S+ +V AK +LKA L+S++ S ++++G Q + G + P Sbjct: 351 IKSAYDQVKAIAQGNLSNTDVQAAKNKLKAGYLMSVESSEGFLDEVGSQALVAGSYMQPS 410 Query: 413 EVFEQVDKITKDDIIMWANYRLQNKPVSMVALGNTSTVPNV 453 V +Q+D + D+I A + + SM A GN P V Sbjct: 411 TVLQQIDSVADADVINAAKKFVSGRK-SMAASGNLGHTPFV 450 >5XTH-AK nrPDB Length = 419 Score = 406 bits (1044), Expect = e-114, Method: Composition-based stats. Identities = 112/432 (25%), Positives = 190/432 (43%), Gaps = 25/432 (5%) Query: 27 RTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQ 86 +KLPNGL IA+ + + +G+F+ AGSR E+ N GT H L + T+ S Sbjct: 5 EFTKLPNGLVIASLENYS-PVSRIGLFIKAGSRYEDFSNLGTTHLLRLTSSLTTKGASSF 63 Query: 87 GIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERDV 146 I IE +G L+ +REN Y + L+ D+ ++ L ++ T R Sbjct: 64 KITRGIEAVGGKLSVTATRENMAYTVECLRGDVDILMEFLLNVTTAP-----EFRRWEVA 118 Query: 147 IIRESEEVDK-----MYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITK 201 ++ ++DK V ++LH Y++ L + P I +T +L ++ Sbjct: 119 DLQPQLKIDKAVAFQNPQTHVIENLHAAAYRN-ALANPLYCPDYRIGKVTSEELHYFVQN 177 Query: 202 NYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIKEN 261 ++ RM L G G V H L Q A+++ + G RG ++N Sbjct: 178 HFTSARMALIGLG-VSHPVLKQVAEQFLN--------MRGGLGLSGAKANYRGGEIREQN 228 Query: 262 TLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSLAN 321 H A E + + Q ++G + G+N+ S L A ++ Sbjct: 229 GDSLVHAAFVAESAVAGSAEANAFSVLQHVLGAGPH-VKRGSNTTSHLHQAVAKATQQPF 287 Query: 322 SYMSFSTSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQLK 381 +F+ SY+DSGL+G+Y ++ + ++ + K I G +S+ +V AK +LK Sbjct: 288 DVSAFNASYSDSGLFGIYTISQATA--AGDVIKAAYNQVKTIAQGNLSNTDVQAAKNKLK 345 Query: 382 AALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKPVSM 441 A L+S++ S +E++G Q + G + P V +Q+D + DII A + + SM Sbjct: 346 AGYLMSVESSECFLEEVGSQALVAGSYMPPSTVLQQIDSVANADIINAAKKFVSGQK-SM 404 Query: 442 VALGNTSTVPNV 453 A GN P V Sbjct: 405 AASGNLGHTPFV 416 >2BCC-B nrPDB Length = 422 Score = 401 bits (1029), Expect = e-112, Method: Composition-based stats. Identities = 113/432 (26%), Positives = 190/432 (43%), Gaps = 25/432 (5%) Query: 27 RTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQ 86 +KLPNGL IA+ + +T+G+F+ AGSR EN N GT+H L + T+ S Sbjct: 8 EITKLPNGLVIASLENYS-PGSTIGVFIKAGSRYENSSNLGTSHLLRLASSLTTKGASSF 66 Query: 87 GIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERDV 146 I IE +G L+ ++REN Y + L++D+ ++ L ++ T Sbjct: 67 KITRGIEAVGGKLSVESTRENMAYTVECLRDDVEILMEFLLNVTTAP-----EFRPWEVA 121 Query: 147 IIRESEEVDK-----MYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITK 201 ++ ++DK V ++LH Y++ L ++ P I +T +L D++ Sbjct: 122 DLQPQLKIDKAVAFQNPQTHVIENLHAAAYRN-ALADSLYCPDYRIGKVTSVELHDFVQN 180 Query: 202 NYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIKEN 261 ++ RM L G G V H L A++ + G RG ++N Sbjct: 181 HFTSARMALVGLG-VSHPVLKNVAEQLLN--------IRGGLGLSGAKAKYRGGEIREQN 231 Query: 262 TLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSLAN 321 H AI E + + Q ++G + G N+ S L A ++ Sbjct: 232 GDSLVHAAIVAESAAIGGAEANAFSVLQHVLGANPH-VKRGLNATSSLYQAVAKGVHQPF 290 Query: 322 SYMSFSTSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQLK 381 +F+ SY+DSGL+G Y ++ + ++ + K I G +S+ V AK +LK Sbjct: 291 DVSAFNASYSDSGLFGFYTISQAAY--AGQVIKAAYNQVKTIAQGNVSNENVQAAKNKLK 348 Query: 382 AALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKPVSM 441 A L+S++ S +E++G Q + G P V +Q+D + D+I A + + SM Sbjct: 349 AKYLMSVESSEGFLEEVGSQALAAGSYNPPSTVLQQIDAVADADVIKAAKKFVS-RQKSM 407 Query: 442 VALGNTSTVPNV 453 A GN P V Sbjct: 408 AASGNLGHTPFV 419 >3L73-B nrPDB Length = 441 Score = 386 bits (991), Expect = e-107, Method: Composition-based stats. Identities = 107/432 (24%), Positives = 195/432 (45%), Gaps = 25/432 (5%) Query: 27 RTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQ 86 +KLPNGL IA+ + ++ +G+F+ AGSR E N GTAH L + T+ S Sbjct: 27 EITKLPNGLIIASLEN-FSPASRIGVFIKAGSRYETTANLGTAHLLRLASPLTTKGASSF 85 Query: 87 GIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERDV 146 I IE +G L+ Y++RE Y + L++ + ++ L ++ T Sbjct: 86 RITRGIEAVGGSLSVYSTREKMTYCVECLRDHVDTVMEYLLNVTTAP-----EFRPWEVT 140 Query: 147 IIRESEEVDKM-----YDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITK 201 ++ +VDK V ++LH YK L + P I IT L ++ Sbjct: 141 DLQPQLKVDKAVAFQSPQVGVLENLHAAAYK-TALANPLYCPDYRIGKITSEQLHHFVQN 199 Query: 202 NYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIKEN 261 N+ RM L G G V H L Q A+++ + G+ G ++N Sbjct: 200 NFTSARMALVGIG-VKHSDLKQVAEQFLN--------IRSGAGTSSAKATYWGGEIREQN 250 Query: 262 TLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSLAN 321 H A+ EG + + + Q ++G I G++ S L ++ + Sbjct: 251 GHSLVHAAVVTEGAAVGSAEANAFSVLQHVLGAGP-LIKRGSSVTSKLYQGVAKATTQPF 309 Query: 322 SYMSFSTSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQLK 381 +F+ +Y+DSGL+G Y ++ + + ++ + + K G +++ +V +AK QLK Sbjct: 310 DASAFNVNYSDSGLFGFYTISQAA--HAGEVIRAAMNQLKAAAQGGVTEEDVTKAKNQLK 367 Query: 382 AALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKPVSM 441 A L+S++ + ++ +IG + + +G +P V +++D +T D++ A + K SM Sbjct: 368 ATYLMSVETAQGLLNEIGSEALLSGTHTAPSVVAQKIDSVTSADVVNAAKKFVSGKK-SM 426 Query: 442 VALGNTSTVPNV 453 A G+ + P + Sbjct: 427 AASGDLGSTPFL 438 >3HDI-A nrPDB Length = 421 Score = 386 bits (991), Expect = e-107, Method: Composition-based stats. Identities = 124/425 (29%), Positives = 210/425 (49%), Gaps = 19/425 (4%) Query: 27 RTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQ 86 T L NG+ I TE + S ++GI+V GSR E+ + NG +HFLEH+ FKGT RS Q Sbjct: 3 NTMTLDNGVRIITEKMSTVRSVSIGIWVGTGSRYESAEENGISHFLEHMFFKGTNTRSAQ 62 Query: 87 GIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERDV 146 I ++IG +NA+TS+E T YYAK L + +A+D LSD+ S +E+ER V Sbjct: 63 EIAEFFDSIGGQVNAFTSKEYTCYYAKVLDDHAGQAIDTLSDMFFHSTFQKEELEKERKV 122 Query: 147 IIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKNYKGD 206 + E + VD D++V D L TY LG ILG ++ + S L+ Y+ + Y GD Sbjct: 123 VFEEIKMVDDTPDDIVHDLLSSATYGKHSLGYPILGTVETLNSFNEGMLRHYMDRFYTGD 182 Query: 207 RMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIKENTLPTT 266 +V++ AG V H++L+ ++ F V + + +G P+F R +++ Sbjct: 183 YVVISVAGNV-HDELIDKIKETFSQVKPTTY-----NYQGEKPMFLPN-RIVRKKETEQA 235 Query: 267 HIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSLANSYMSF 326 H+ + G+ D + + ++G + S L + L S S+ Sbjct: 236 HLCLGYPGLPIGDKDVYALVLLNNVLGG---------SMSSRLFQDIREKRGLCYSVFSY 286 Query: 327 STSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQLKAALLL 386 +S+ DSG+ +Y T ++ + +V I + + +++ E+ K QLK +L+L Sbjct: 287 HSSFRDSGMLTIYAGTGHDQLDD--LVYSIQETTSALAEKGLTEKELENGKEQLKGSLML 344 Query: 387 SLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKPVSMVALGN 446 SL+ + + + G+ + K S +E+ EQ++ + K D+ A L P S+ + Sbjct: 345 SLESTNSRMSRNGKNELLLKKHRSLDEMIEQINAVQKQDVSRLAKILLSASP-SISLINA 403 Query: 447 TSTVP 451 +P Sbjct: 404 NGELP 408 >6GIQ-A nrPDB Length = 457 Score = 354 bits (909), Expect = 3e-98, Method: Composition-based stats. Identities = 120/453 (26%), Positives = 226/453 (49%), Gaps = 28/453 (6%) Query: 3 SRTAS-KFRNTRRLLSTISSQIPGTRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAE 61 S+T S +F+ R L + +++ P ++L NG+ +ATE+ P+ +A+VG+ +G+ E Sbjct: 7 SKTVSNQFK--RSLATAVAT--PKAEVTQLSNGIVVATEHNPSAHTASVGVVFGSGAANE 62 Query: 62 NVKNNGTAHFLEHLAFKGTQNRSQQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPK 121 N NNG ++ +++ F +N + E G L++ SR+ Y SL K Sbjct: 63 NPYNNGVSNLWKNI-FLSKENSAVAAKE------GLALSSNISRDFQSYIVSSLPGSTDK 115 Query: 122 AVDILSDILTK---SVLDNSAIERERDVIIRESEEVDKM-YDEVVFDHLHEITYKDQPLG 177 ++D L+ + ++L +S E + ++++ ++ ++ + V +HLH +++ PL Sbjct: 116 SLDFLNQSFIQQKANLLSSSNFEATKKSVLKQVQDFEENDHPNRVLEHLHSTAFQNTPLS 175 Query: 178 RTILGPIKNIKSITRTDLKDYITKNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSES 237 G +++++++ DL+ + ++ V+ G G + HE LV + + Sbjct: 176 LPTRGTLESLENLVVADLESFANNHFLNSNAVVVGTGNIKHEDLVNSIESKNLSLQTGTK 235 Query: 238 PVPLGSPRGPLPVFCRGERFIKENTLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDR 297 PV F E ++++TLP I++A+EG ++P+YFVA I G+++ Sbjct: 236 PV-----LKKKAAFLGSEVRLRDDTLPKAWISLAVEGEPVNSPNYFVAKLAAQIFGSYN- 289 Query: 298 AIGTGTNSPSPLAVAASQNGSLANSYMSFSTSYADSGLWGMYIVTDSNEHNVQLIVNEIL 357 A + + Q L +++ FS SY DSGLWG T + + +++ L Sbjct: 290 AFEPASRLQGIKLLDNIQEYQLCDNFNHFSLSYKDSGLWGFSTATRNVTM-IDDLIHFTL 348 Query: 358 KEWKRIKSGKISDAEVNRAKAQLKAALLLSLDGSTAIVED---IGRQVVTTGKRLSPEEV 414 K+W R+ + ++D EV RAK+ LK L L S V D +G +V+ G +LS E Sbjct: 349 KQWNRL-TISVTDTEVERAKSLLKLQ-LGQLYESGNPVNDANLLGAEVLIKGSKLSLGEA 406 Query: 415 FEQVDKITKDDIIMWANYRLQNKPVSMVALGNT 447 F+++D IT D+ WA RL ++ +++ G Sbjct: 407 FKKIDAITVKDVKAWAGKRLWDQDIAIAGTGQI 439 >1HR7-A nrPDB Length = 475 Score = 354 bits (909), Expect = 3e-98, Method: Composition-based stats. Identities = 114/423 (26%), Positives = 200/423 (47%), Gaps = 8/423 (1%) Query: 27 RTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQ 86 + S L NGL +AT P SA +G+++DAGSR E G H L+ LAFK T++ + Sbjct: 7 KLSSLANGLKVATSNTPGHFSA-LGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEGR 65 Query: 87 GIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERDV 146 + +E +G + +SREN +Y A +D+ K + ++S+ + + ++ ++ Sbjct: 66 AMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKLS 125 Query: 147 IIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKNYKGD 206 E +EV + V+ + LH Y + LG ++ P I SI++ L DY K Y + Sbjct: 126 AEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRGLIPSISKYYLLDYRNKFYTPE 185 Query: 207 RMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIKENTLPTT 266 V A G V HEK ++ KY G + P+ + C + N Sbjct: 186 NTVAAFVG-VPHEKALELTGKYLGDWQSTHPPITKKVAQYTGGESCIPPAPVFGNLPELF 244 Query: 267 HIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSP--SPLAVAASQNGSLANSYM 324 HI I EG+ PD + Q ++G G S L + + Sbjct: 245 HIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFVENCV 304 Query: 325 SFSTSYADSGLWGMYI--VTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQLKA 382 +F+ SY+DSG++G+ + + + V++I ++ + K ++++ EV+RAK QLK+ Sbjct: 305 AFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFAN-KDLRLTEDEVSRAKNQLKS 363 Query: 383 ALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKPVSMV 442 +LL++L+ +ED+GRQV+ G+++ E+ +++ + DDI A V+ Sbjct: 364 SLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFTGN-VNNA 422 Query: 443 ALG 445 G Sbjct: 423 GNG 425 >4NNZ-A nrPDB Length = 439 Score = 328 bits (841), Expect = 3e-90, Method: Composition-based stats. Identities = 93/429 (21%), Positives = 170/429 (39%), Gaps = 29/429 (6%) Query: 26 TRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQ 85 T L NGL + ++ GS E G +H LEH+ FKG++ Sbjct: 7 THEFSLDNGLKVIVREDHRAPVVVSQLWYRIGSSYETPGLTGLSHALEHMMFKGSRKLGP 66 Query: 86 QGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERD 145 + ++G+ NA+T+ + T YY ++ +P A+++ +D + L + E + Sbjct: 67 GEASRVLRDLGAEENAFTTDDYTAYYQVLARDRLPVALEMEADRMAHLSLPVDQFKSEIE 126 Query: 146 VIIRESE-EVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKNYK 204 VI E D + + F+ Y +G + +++ +T DL+ + Y Sbjct: 127 VIKEERRLRTDDNPNALAFERFKAAAYPASGYHTPTIGWMADLQRMTIDDLRHWYESWYA 186 Query: 205 GDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIK---EN 261 + L G V +++ A++YFG +P + P R PL + GER +K Sbjct: 187 PNNATLVVVGDVTADEVKTLAKRYFGEIPWRQLP----PARKPLELAEPGERRLKLYVRT 242 Query: 262 TLPTTHIAIALEGVSWSA-PDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSLA 320 LP + + + S P AL R IG + +A+ Sbjct: 243 QLPNLIMGFNVPSLGSSENPREVNAL----------RLIGALLDGGYSARLASRLER--G 290 Query: 321 NSYMSFSTSYADSGLWGMYIVTDSNEHNVQ------LIVNEILKEWKRIKSGKISDAEVN 374 ++ +++Y D+ G + S NVQ + + K+ +K S AE+ Sbjct: 291 EELVAGASTYYDAFNRGDSLFVLSATPNVQKGKTLEQVEAGLWKQLDDLKQNPPSAAEIE 350 Query: 375 RAKAQLKAALLLSLDGSTAIVEDIGR-QVVTTGKRLSPEEVFEQVDKITKDDIIMWANYR 433 R +AQ+ A ++ D A IG+ + V +L ++ E + +T DDI A Sbjct: 351 RVRAQMIAGMVYEKDSIAAQASSIGQLESVGLSWKLIDQD-LEALKAVTPDDIQKAARTY 409 Query: 434 LQNKPVSMV 442 +++ Sbjct: 410 FTPSRLTLA 418 >3EOQ-A nrPDB Length = 406 Score = 302 bits (774), Expect = 2e-82, Method: Composition-based stats. Identities = 105/403 (26%), Positives = 178/403 (44%), Gaps = 24/403 (5%) Query: 27 RTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQ 86 R ++L NGL + E +P S +G FV G+R E + +G +HFLEH+ FKG ++ Sbjct: 3 REAELRNGLRVIAEVVPGARSVALGYFVKTGARDETKEESGVSHFLEHMVFKGPEDMDAL 62 Query: 87 GIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERDV 146 + + +G+ NA+TS E TVYY L E + + + +L + L + E+ V Sbjct: 63 AVNRAFDRMGAQYNAFTSEEATVYYGAVLPEFAYDLLGLFAKLL-RPALREEDFQTEKLV 121 Query: 147 IIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKNYKGD 206 I+ E + ++ ++ PLG ++LG ++I ++TR + Y + Y Sbjct: 122 ILEEIARYQDRPGFMAYEWARARFFQGHPLGNSVLGTRESITALTREGMAAYHRRRYLPK 181 Query: 207 RMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPL-PVFCRGER-FIKENTLP 264 MVLA G VD ++L+ A++ P+ E+ PL P F ER + K L Sbjct: 182 NMVLAATGRVDFDRLLAEAERLTEAWPEGEAE----RAYPPLTPAFGVEERPYEKARAL- 236 Query: 265 TTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSLANSYM 324 ++ GV++ F ++G L A G Sbjct: 237 --YLVALFPGVAYQEEARFPGQVLAHLLGEE---------GSGRLHFALVDKGL--AEVA 283 Query: 325 SFSTSYAD-SGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQLKAA 383 SF AD +G + Y+ D L V + +E R+ + + EV RAK L Sbjct: 284 SFGLEEADRAGTFHAYVQADPARKGEVLAV--LQEELDRLGREGVGEEEVERAKTPLATG 341 Query: 384 LLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDI 426 L+ + + + +G + + TG+ LS EEV +V ++T ++ Sbjct: 342 LVFAGETPMQRLFHLGMEYLYTGRYLSLEEVKARVQRVTSREV 384 >5EUF-A nrPDB Length = 419 Score = 298 bits (762), Expect = 3e-81, Method: Composition-based stats. Identities = 85/423 (20%), Positives = 176/423 (41%), Gaps = 15/423 (3%) Query: 23 IPGTRTSKLPNGLTIATEYIPN-TSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQ 81 +P + L NGL + + + N T V + GSR E + +G AH LEHL FK T+ Sbjct: 5 LPKHESVTLKNGLQVVSVPLENKTGVIEVDVLYKVGSRNEVMGKSGIAHMLEHLNFKSTK 64 Query: 82 NRSQQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIE 141 N + ++ G NA TS + T Y+ K+ + ++ K++++ ++ + L Sbjct: 65 NLKAGEFDKIVKRFGGVSNASTSFDITRYFIKTSEANLDKSLELFAETMGSLNLKEDEFL 124 Query: 142 RERDVIIRESE-EVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYIT 200 ER V+ E D +++ Y P T +G + +I++ T D+K + + Sbjct: 125 PERQVVAEERRWRTDNSPIGMLYFRFFNTAYVYHPYHWTPIGFMDDIQNWTLKDIKKFHS 184 Query: 201 KNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPK-SESPVPLGSPRGPLPVFCRGERFIK 259 Y+ ++ G V+ +K+ + +K+F + E +P + P R K Sbjct: 185 LYYQPKNAIVLVVGDVNSQKVFELTKKHFESLKNLDEKAIPTPYMKEPKQDGARTAVVHK 244 Query: 260 ENTLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSL 319 + + +A+ + ++ D A ++G S L L Sbjct: 245 -DGVHLEWVALGYKVPAFKHKDQVALDALSKLLGEG---------KSSWLQSELVDKKRL 294 Query: 320 ANSYMSFSTSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQ 379 A+ S + D ++ ++I + + + EI+ +++K G+I+ AE+++ K Sbjct: 295 ASQAFSHNMQLQDESVF-LFIAGGNPNIKAEALQKEIVALLEKLKKGEITQAELDKIKIN 353 Query: 380 LKAALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYRLQNKPV 439 KA + +L+ S+ + + + + +Q + D++ AN ++ Sbjct: 354 QKADFISNLESSSDVAG-LFADYLVQNDLQGLTDYQQQFLDLKVSDLVRVANEYFKDTQS 412 Query: 440 SMV 442 + V Sbjct: 413 TTV 415 >1Q2L-A nrPDB Length = 939 Score = 183 bits (463), Expect = 2e-46, Method: Composition-based stats. Identities = 55/224 (24%), Positives = 93/224 (41%), Gaps = 11/224 (4%) Query: 25 GTRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRS 84 + +L NG+ + P + + V GS + G AH+LEH++ G++ Sbjct: 20 QYQAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYP 79 Query: 85 QQGIELEIENI-GSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERE 143 Q E + G NA T+ T +Y + + +P AVD L+D + + +LD ERE Sbjct: 80 QADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERE 139 Query: 144 RDVIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSIT-------RTDLK 196 R+ + E + + D + + T G G N+++++ + LK Sbjct: 140 RNAVNAEL-TMARTRDGMRMAQVSAETINPAHPGSKFSG--GNLETLSDKPGNPVQQALK 196 Query: 197 DYITKNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVP 240 D+ K Y + M +L + A FG VP ES P Sbjct: 197 DFHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKP 240 >5CIO-A nrPDB Length = 793 Score = 177 bits (448), Expect = 1e-44, Method: Composition-based stats. Identities = 61/255 (23%), Positives = 99/255 (38%), Gaps = 22/255 (8%) Query: 30 KLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQ-GI 88 +L NGL + P +A + ++AGS G AH LEH+ F+G+ N S Q G+ Sbjct: 31 QLDNGLAVRAISTPGAEAAAALVRIEAGSFQAPAAWPGLAHLLEHMLFRGSANFSAQDGL 90 Query: 89 ELEIENIGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERDVII 148 + G LNA T T ++ + + + + + LSD+L L AI +E +VI Sbjct: 91 MGWTQAAGGRLNATTQATQTAFFFEVGADPLAEGLARLSDMLAAPQLAAEAIAQEIEVID 150 Query: 149 RE----------SEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDY 198 E E + FD LH + +I ++ + L+ + Sbjct: 151 AEYRLLRADGETRCEAAQRQMFSGFDALHRFHIGSRA------AFGSDISALQQA-LRQF 203 Query: 199 ITKNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFI 258 Y+ M L G E+L AQ+Y G +P + P P P+ + + Sbjct: 204 HHHYYRAPNMTLWLQGPQSLEQLHALAQRYGGGLPSGSATPPETLP----PLAAGQDYTL 259 Query: 259 KENTLPTTHIAIALE 273 P + L Sbjct: 260 SLPGAPQLRLVFTLP 274 >3CX5-B nrPDB Length = 352 Score = 168 bits (426), Expect = 3e-42, Method: Composition-based stats. Identities = 82/359 (22%), Positives = 143/359 (39%), Gaps = 65/359 (18%) Query: 35 LTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQGIELEIEN 94 LT++ P T +T+ + V GSR +G AH L F+ T RS + E E Sbjct: 1 LTVSARDAP-TKISTLAVKVHGGSRYAT--KDGVAHLLNRFNFQNTNTRSALKLVRESEL 57 Query: 95 IGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSV-----LDNSAIERER-DVII 148 +G + RE A L++D+P V+ L+D+L K+ L S + R D + Sbjct: 58 LGGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAV 117 Query: 149 RESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKNYKGDRM 208 E V D L+ IT++ + LG +L ++ ++ D+KD+ K Y + + Sbjct: 118 AEQCPVKSAED-----QLYAITFR-KGLGNPLL--YDGVERVSLQDIKDFADKVYTKENL 169 Query: 209 VLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIKENTLPTTHI 268 ++G V+ + +RF+ E+ L T Sbjct: 170 EVSGENVVEADL----------------------------------KRFVDESLLSTLPA 195 Query: 269 AIALEGVSWSAPDYFVALATQA-IVGNWDRAIGTGTNSPSPL-AVAASQNGSLANSYMSF 326 +L VS S P +F+ + +G+ AIG N S + + A S +S Sbjct: 196 GKSL--VSKSEPKFFLGEENRVRFIGDSVAAIGIPVNKASLAQYEVLANYLTSALSELSG 253 Query: 327 STS------YADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVNRAKAQ 379 S + D GL+ +++ + + ++ + I K +K GK +N K + Sbjct: 254 LISSAKLDKFTDGGLFTLFV----RDQDSAVVSSNIKKIVADLKKGKDLSPAINYTKLK 308 >3GO9-A nrPDB Length = 492 Score = 83.8 bits (205), Expect = 1e-16, Method: Composition-based stats. Identities = 52/257 (20%), Positives = 89/257 (34%), Gaps = 20/257 (7%) Query: 24 PGTRTSKLPNGLTIATEYIPNTSS--ATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQ 81 P + KL NG + P S + + V+ GS +EN + G AH L LA + Sbjct: 24 PAWQQGKLDNGFSWQLLATPQRPSDRIELRLIVNTGSLSENTQEVGFAHLLPRLALMSSA 83 Query: 82 NRSQQGIE----LEIENIGSHLNAYTSRENTVYYAKS---LQEDIPKAVDILSDILTKSV 134 + + ++ I+N A TS + T+Y + + A+ LSD Sbjct: 84 SFTPAQLQSLWQQGIDNERPLPPAITSYDFTLYSLSLPNNRPDLLKDALAWLSDTAGNLA 143 Query: 135 LDNSAIERERDVIIRESEEVDKMYDEVVFDH-LHEITYKDQPLGRTILGPIKNIKSITRT 193 + + + + E + + L + G+ + P+ Sbjct: 144 VSEQTVNAALNTATDPIATFPQNIQEPWWRYRLKGSSLIGHDPGQPVTQPVD------VE 197 Query: 194 DLKDYITKNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSE---SPVPLGSPRGPLPV 250 LK + + Y D M L G VD + K F + + V +P P PV Sbjct: 198 KLKQFYQQWYTPDAMTLYVVGNVDSRSIAAQISKAFSELKGKRTAPAAVATLAPLPPEPV 257 Query: 251 FCRGERFIKENTLPTTH 267 E+ ++TL Sbjct: 258 SLMNEQ-AAQDTLSLMW 273 >2FGE-A nrPDB Length = 995 Score = 79.5 bits (194), Expect = 3e-15, Method: Composition-based stats. Identities = 71/388 (18%), Positives = 135/388 (34%), Gaps = 42/388 (10%) Query: 34 GLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQGIELEIE 93 G + + + + +F R + G H L+H G++ + +E+ Sbjct: 46 GCEVMSVSNEDENKVFGVVF-----RTPPKDSTGIPHILQHSVLCGSRKYPVKEPFVELL 100 Query: 94 NIGSH--LNAYTSRENTVYYAKSLQ-EDIPKAVDILSDILTKSVLDNSA--IERE----- 143 H LNA+T + T Y S +D VD+ D + + A ++E Sbjct: 101 KGSLHTFLNAFTYPDRTCYPVASTNTKDFYNLVDVYLDAVFFPKCVDDAHTFQQEGWHYE 160 Query: 144 ----------RDVIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRT 193 + V+ E + V D ++ + + G G K+I ++T Sbjct: 161 LNDPSEDISYKGVVFNEMKGVYSQPDNILGRIAQQALSPENTYGVDSGGDPKDIPNLTFE 220 Query: 194 DLKDYITKNYKGDRMVLAGAGA---VDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPV 250 + K++ + Y + G V +++ F P S PV Sbjct: 221 EFKEFHRQYYHPSNARIWFYGDDDPVHRLRVLSEYLDMFEASPSPNSSKIKFQKLFSEPV 280 Query: 251 FCRGERFI-KENTLPTTHIAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPL 309 + ++ L H+ V+W + + L TQ +G D + SPL Sbjct: 281 RLVEKYPAGRDGDLKKKHMLC----VNWLLSEKPLDLQTQLALGFLDHLMLGTP--ASPL 334 Query: 310 AVAASQNGSLANSYMSFSTSYADSGL---WGMYIVTDSNEHNVQLIVNEILKEWKRIKSG 366 ++G L + +S S D L +G+ + S E NVQ + I+ K++ Sbjct: 335 RKILLESG-LGEALVSSGLS--DELLQPQFGIGLKGVSEE-NVQKVEELIMDTLKKLAEE 390 Query: 367 KISDAEVNRAKAQLKAALLLSLDGSTAI 394 + V + ++ +L + GS Sbjct: 391 GFDNDAVEASMNTIEFSLRENNTGSFPR 418 >5XL8-A nrPDB Length = 503 Score = 36.8 bits (83), Expect = 0.023, Method: Composition-based stats. Identities = 28/168 (16%), Positives = 54/168 (32%), Gaps = 8/168 (4%) Query: 5 TASKFRNTRRLLSTISSQIPGTRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVK 64 T F+N R+ + + KL G+ E + F++ G + Sbjct: 288 TTKPFQNISRIAVGDCPRYVKQGSLKLATGMRNIPEKASRGLFGAIAGFIENGWQGLIDG 347 Query: 65 NNGTAHFLEHLAFKGTQNRSQQGIEL-EIENIGSHLNAYTSRENTVY-YAKSLQEDIPKA 122 G H +GT + I+ I LN + N Y + E + Sbjct: 348 WYG----FRHQNAEGTGTAADLKSTQAAIDQINGKLNRLIEKTNDKYHQIEKEFEQVEGR 403 Query: 123 VDILSDILTKSVLDNSAIERERDVIIRESEEVDKMYDEV--VFDHLHE 168 + L + + +D + E V + +D E+ +F+ + Sbjct: 404 IQDLEKYVEDTKIDLWSYNAELLVALENQHTIDVTDSEMNKLFERVRR 451 >6GCS-A nrPDB Length = 728 Score = 34.1 bits (76), Expect = 0.13, Method: Composition-based stats. Identities = 31/172 (18%), Positives = 57/172 (33%), Gaps = 30/172 (17%) Query: 37 IATEYIPN-TSSATVGIFVDAGSRAENVKNNGTAHFLEHLAFKGTQNRSQQGIELEIENI 95 +A IP G D G++ +V G A+ + + T+ RSQ Sbjct: 558 VAASDIPADAFVVYQGHNGDVGAQFADVVLPGAAYTEKAGTYVNTEGRSQISRAATGPPG 617 Query: 96 GSHLNAYTSRENTVYYAKSLQ-EDIPKAVDILSDILTKSVLDNSAIERERDVIIRESEEV 154 G+ + R + Y +L ED + D L++I Sbjct: 618 GAREDWKILRAVSEYLGVALPYEDAYEVRDRLAEI------------------------- 652 Query: 155 DKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKNYKGD 206 V +D + + D + +++GP ++ + L + I Y D Sbjct: 653 --SPSLVRYDLVEPTVFGDVAVQHSLVGPNGSVTP-SSAPLTETIENFYMTD 701 >5UBV-A nrPDB Length = 246 Score = 32.1 bits (71), Expect = 0.52, Method: Composition-based stats. Identities = 34/189 (17%), Positives = 59/189 (31%), Gaps = 12/189 (6%) Query: 2 FSRTASKFRNTRRLLSTISSQIPGTRTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAE 61 F R KF N + ++P P G A V F +GS + Sbjct: 24 FLRNPEKFSN-------LGGKLPKGVLLVGPPGTGKTLLARAVAGEAGVPFFYMSGSEFD 76 Query: 62 NVKNNGTAHFLEHLAFKGTQNRSQQGIELEIENIGSHLNAYTSRENTVYYAKSLQEDIPK 121 + A + L E++ IG N SR+ T Y ++L + + + Sbjct: 77 EIYVGVGAKRVRELFNAAKAKAPSIVFIDELDAIGGRRN---SRDAT-YVRQTLNQLLTE 132 Query: 122 AVDILSDILTKSVLDNSAIERERDVIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTIL 181 +D + +L + D + D+ + D I + + Sbjct: 133 -MDGFAQNSGVIILGATNFPESLDKALTRPGRFDRHVHVSLPDVRGRIAILKHHAKKIKI 191 Query: 182 GPIKNIKSI 190 G NI +I Sbjct: 192 GSDVNIAAI 200 >1SW7-A nrPDB Length = 248 Score = 32.1 bits (71), Expect = 0.56, Method: Composition-based stats. Identities = 17/52 (32%), Positives = 27/52 (51%), Gaps = 1/52 (1%) Query: 409 LSPEEVFEQVDKITKDDIIMWANYRLQNKPVSMVALGNTSTVPNVSYIEEKL 460 ++ + VFEQ I D++ W+ L +PV + GN+ST + EKL Sbjct: 138 ITEKVVFEQTKAIA-DNVKDWSKVVLAYEPVWAIGTGNSSTPQQAQEVHEKL 188 >3PDI-A nrPDB Length = 483 Score = 31.4 bits (69), Expect = 0.93, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 35/84 (41%), Gaps = 14/84 (16%) Query: 390 GSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMW----ANYRLQN-----KPVS 440 + ++D+G +VV TG + S EE ++ ++ DD+ M A L+ + Sbjct: 346 SVVSALQDLGMKVVATGTKKSTEEDKARIRELMGDDVKMLDEGNARVLLKTVDEYQADIL 405 Query: 441 MVALGNT-----STVPNVSYIEEK 459 + N VP + +E+ Sbjct: 406 IAGGRNMYTALKGRVPFLDINQER 429 >5XW0-A nrPDB Length = 460 Score = 31.0 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 24/186 (12%), Positives = 52/186 (27%), Gaps = 19/186 (10%) Query: 208 MVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIKENTLPTTH 267 +++ G G+ E++ AQ L S G P + P H Sbjct: 257 LIINGEGSFTPEEIELIAQTKVER-------KQLASIVGAAPFSDANKFKYIAGARPWVH 309 Query: 268 IAIALEGVSWSAPDYFVALATQAIVGNWDRAIGTGTNSPSPLAVAASQNGSLANSYMSFS 327 + + + + Q ++ + I G+N + + + + Sbjct: 310 VGKVDVALPSATQNEISGEEAQVLINAGCKFIAEGSNMGCTQEAIDTFEAHRTANAGAAA 369 Query: 328 TSYADSGLWGMYIVTDSNEHNVQLIVNEILKEWKRIKSGKISDAEVN-RAKAQLKAALLL 386 YA N + L+ + + EV+ R K ++ Sbjct: 370 IWYAPG-----------KAANAGGVAVSGLEMAQNSARLSWTSEEVDARLKDIMRDCFKN 418 Query: 387 SLDGST 392 L+ + Sbjct: 419 GLETAQ 424 >5A79-A nrPDB Length = 198 Score = 30.6 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 22/118 (18%), Positives = 38/118 (32%), Gaps = 14/118 (11%) Query: 96 GSHLNAYTSRENTVYYAKSLQEDIPKAVDI-----LSDILTKSVLDNSAIERERDVIIRE 150 G + + +SR Y +L D+P VD I + + L R I E Sbjct: 48 GINFSVASSRSQVAEYLAALDRDLPADVDRRFAGARGQIGSPNYLPAPKFFRLDKRTIAE 107 Query: 151 SEEVDKMYD------EVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKN 202 + ++ D ++ + T P + P +N+ LKD Sbjct: 108 LTRLSRLTDQPHNNRDIELNRAKRATTNPSPPAQA---PSENLTLRDVQPLKDSALHY 162 >1TA3-B nrPDB Length = 303 Score = 27.9 bits (60), Expect = 9.2, Method: Composition-based stats. Identities = 14/86 (16%), Positives = 29/86 (33%), Gaps = 3/86 (3%) Query: 374 NRAKAQLKAALLLSLDGSTAIVEDIGRQVVTTGKRLSPEEVFEQVDKITKDDIIMWANYR 433 + AK Q A+ + ++ IG Q + S E + + + A Sbjct: 179 SYAKTQAMASYVKKWLAEGVPIDGIGSQAHYSSSHWSSTEAAGALSSLANTGVSEVA--- 235 Query: 434 LQNKPVSMVALGNTSTVPNVSYIEEK 459 + ++ A + + N E+K Sbjct: 236 ITELDIAGAASSDYLNLLNACLNEQK 261 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.118 0.268 Lambda K H 0.267 0.0359 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,156,635 Number of Sequences: 36641 Number of extensions: 484503 Number of successful extensions: 1331 Number of sequences better than 10.0: 29 Number of HSP's better than 10.0 without gapping: 49 Number of HSP's successfully gapped in prelim test: 13 Number of HSP's that attempted gapping in prelim test: 1157 Number of HSP's gapped (non-prelim): 68 length of query: 462 length of database: 10,336,785 effective HSP length: 100 effective length of query: 362 effective length of database: 6,672,685 effective search space: 2415511970 effective search space used: 2415511970 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 60 (27.9 bits)