BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P10253 (952 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5KZW-A nrPDB 1802 0.0 3L4Y-A nrPDB 732 0.0 3LPO-A nrPDB 714 0.0 3TOP-A nrPDB 631 0.0 3WEN-A nrPDB 554 e-158 5HJR-A nrPDB 340 1e-93 5IEF-A nrPDB 334 9e-92 5DKX-A nrPDB 312 4e-85 5DJW-A nrPDB 304 1e-82 2G3M-A nrPDB 252 7e-67 6JR6-A nrPDB 244 2e-64 3POC-A nrPDB 238 9e-63 5I24-A nrPDB 192 6e-49 5JOV-A nrPDB 141 1e-33 5F7C-A nrPDB 136 5e-32 1XSK-A nrPDB 130 2e-30 5I0E-B nrPDB 103 3e-22 5X3I-A nrPDB 96 6e-20 5AEG-A nrPDB 92 1e-18 6DRU-A nrPDB 85 1e-16 5OHS-A nrPDB 70 5e-12 4XPS-A nrPDB 52 1e-06 1HI7-A nrPDB 38 0.025 1PSP-A nrPDB 33 0.44 1L5X-A nrPDB 32 1.8 5YYS-A nrPDB 30 3.7 >5KZW-A nrPDB Length = 874 Score = 1802 bits (4667), Expect = 0.0, Method: Compositional matrix adjust. Identities = 872/874 (99%), Positives = 873/874 (99%) Query: 79 PTQCDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFPPSYPSYKL 138 PTQCDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFPPSYPSYKL Sbjct: 1 PTQCDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFPPSYPSYKL 60 Query: 139 ENLSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETP 198 ENLSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETP Sbjct: 61 ENLSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETP 120 Query: 199 HVHSRAPSPLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYIT 258 HVHSRAPSPLYSVEFSEEPFGVIV RQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYIT Sbjct: 121 HVHSRAPSPLYSVEFSEEPFGVIVHRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYIT 180 Query: 259 GLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAM 318 GLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAM Sbjct: 181 GLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAM 240 Query: 319 DVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGY 378 DVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGY Sbjct: 241 DVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGY 300 Query: 379 SSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRY 438 SSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRY Sbjct: 301 SSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRY 360 Query: 439 MMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAW 498 MMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAW Sbjct: 361 MMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAW 420 Query: 499 WEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATIC 558 WEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATIC Sbjct: 421 WEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATIC 480 Query: 559 ASSHQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVW 618 ASSHQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVW Sbjct: 481 ASSHQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVW 540 Query: 619 SSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLL 678 SSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLL Sbjct: 541 SSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLL 600 Query: 679 SLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTW 738 SLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTW Sbjct: 601 SLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTW 660 Query: 739 TVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAI 798 TVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVP+EALGSLPPPPAAPREPAI Sbjct: 661 TVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPIEALGSLPPPPAAPREPAI 720 Query: 799 HSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELF 858 HSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELF Sbjct: 721 HSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELF 780 Query: 859 WDDGESLEVLERGAYTQVIFLARNNTIVNELVRVTSEGAGLQLQKVTVLGVATAPQQVLS 918 WDDGESLEVLERGAYTQVIFLARNNTIVNELVRVTSEGAGLQLQKVTVLGVATAPQQVLS Sbjct: 781 WDDGESLEVLERGAYTQVIFLARNNTIVNELVRVTSEGAGLQLQKVTVLGVATAPQQVLS 840 Query: 919 NGVPVSNFTYSPDTKVLDICVSLLMGEQFLVSWC 952 NGVPVSNFTYSPDTKVLDICVSLLMGEQFLVSWC Sbjct: 841 NGVPVSNFTYSPDTKVLDICVSLLMGEQFLVSWC 874 >3L4Y-A nrPDB Length = 875 Score = 732 bits (1889), Expect = 0.0, Method: Compositional matrix adjust. Identities = 392/884 (44%), Positives = 524/884 (59%), Gaps = 48/884 (5%) Query: 89 RFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFPPSYPSYKLE-NLSSSEMG 147 R +C PD+ T+ C+ RGCC+ P QGA + PWC++ ++ SY +E NL ++ G Sbjct: 12 RINCIPDQPPTKATCDQRGCCWNP-----QGA-VSVPWCYYSKNH-SYHVEGNLVNTNAG 64 Query: 148 YTATLTR--TTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETPHVHS--- 202 +TA L ++P F ++ + L +T NR HF + D N R+EVP E HV S Sbjct: 65 FTARLKNLPSSPVF-GSNVDNVLLTAEYQTSNRFHFKLTDQTNNRFEVPHE--HVQSFSG 121 Query: 203 -RAPSPLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYITGLA 261 A S Y VE S +PF + V R+ + RVL ++++ PL FADQFLQLST LPS + GL Sbjct: 122 NAAASLTYQVEISRQPFSIKVTRRSNNRVLFDSSIGPLLFADQFLQLSTRLPSTNVYGLG 181 Query: 262 EHL-SPLMLSTSWTRITLWNRDLAPT-PGANLYGSHPFYLALEDG-GSAHGVFLLNSNAM 318 EH+ +W ++NRD P G NLYG+ F+L LED G + GVFL+NSNAM Sbjct: 182 EHVHQQYRHDMNWKTWPIFNRDTTPNGNGTNLYGAQTFFLCLEDASGLSFGVFLMNSNAM 241 Query: 319 DVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGY 378 +VVLQP+PA+++R+ GGILD Y+FLG P+ VVQ+YL+++G P +P YW LGFHL R+ Y Sbjct: 242 EVVLQPAPAITYRTIGGILDFYVFLGNTPEQVVQEYLELIGRPALPSYWALGFHLSRYEY 301 Query: 379 SSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRY 438 + R+VVE A P DVQ D+DYMD RRDFT++ F+ FP V ELH G++ Sbjct: 302 GTLDNMREVVERNRAAQLPYDVQHADIDYMDERRDFTYDSVDFKGFPEFVNELHNNGQKL 361 Query: 439 MMIVDPAISSSGPAGS-YRPYDEGLRRGVFITNETG-QPLIGKVWPGSTAFPDFTNPTAL 496 ++IVDPAIS++ + Y PYD G +++ + G PLIG+VWPG T FPD+TNP Sbjct: 362 VIIVDPAISNNSSSSKPYGPYDRGSDMKIWVNSSDGVTPLIGEVWPGQTVFPDYTNPNCA 421 Query: 497 AWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAAT 556 WW FH+QV FDG+WIDMNE SNF+ GS GC N L NPP+ P ++ G L T Sbjct: 422 VWWTKEFELFHNQVEFDGIWIDMNEVSNFVDGSVSGCSTNNLNNPPFTPRILDGYLFCKT 481 Query: 557 ICASSHQFLSTHYNLHNLYGLTEAIASHRALVKAR-GTRPFVISRSTFAGHGRYAGHWTG 615 +C + Q Y++HNLYG + A+A+ A R F+++RSTFAG G++A HW G Sbjct: 482 LCMDAVQHWGKQYDIHNLYGYSMAVATAEAAKTVFPNKRSFILTRSTFAGSGKFAAHWLG 541 Query: 616 DVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHN 675 D ++W+ L S+P +L+FNL G+P+VG D+CGF +T EELC RW QLGAFYPF RNHN Sbjct: 542 DNTATWDDLRWSIPGVLEFNLFGIPMVGPDICGFALDTPEELCRRWMQLGAFYPFSRNHN 601 Query: 676 SLLSLPQEPYSFSEPA--QQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPK 733 Q+P SF + + R L +RY LLP+LYTLF +AH G+TVARPL EF + Sbjct: 602 GQGYKDQDPASFGADSLLLNSSRHYLNIRYTLLPYLYTLFFRAHSRGDTVARPLLHEFYE 661 Query: 734 DSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAP 793 D+STW V Q LWG LLITPVL G +V Y P WYD +T GS Sbjct: 662 DNSTWDVHQQFLWGPGLLITPVLDEGAEKVMAYVPDAVWYDYET------GS-------- 707 Query: 794 REPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEA 853 + Q V + P D I +HLR GYI P Q P TT SR+ P+ L +AL + EA Sbjct: 708 ---QVRWRKQKVEMELPGDKIGLHLRGGYIFPTQQPNTTTLASRKNPLGLIIALDENKEA 764 Query: 854 RGELFWDDGESLEVLERGAYTQVIF-LARNNTIVNELVRVTSEGAGLQLQKVTVLGVATA 912 +GELFWDDGE+ + + Y F + +N VN + L ++ +LG Sbjct: 765 KGELFWDDGETKDTVANKVYLLCEFSVTQNRLEVNISQSTYKDPNNLAFNEIKILGTEEP 824 Query: 913 PQ-QVLSNGVPVS---NFTYSPDTKVLDIC-VSLLMGEQFLVSW 951 V NGVP TY + KV I + LL+GE + V W Sbjct: 825 SNVTVKHNGVPSQTSPTVTYDSNLKVAIITDIDLLLGEAYTVEW 868 >3LPO-A nrPDB Length = 898 Score = 714 bits (1843), Expect = 0.0, Method: Compositional matrix adjust. Identities = 381/910 (41%), Positives = 539/910 (59%), Gaps = 47/910 (5%) Query: 63 PGPRDAQAHPGRPRAVPTQCDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQM 122 P + G R P + P N R +C P++ T+ C RGCC+ P L Sbjct: 15 PTTENLYFQSGIRRKCPNVLNDPVNVRINCIPEQFPTEGICAQRGCCWRPWNDSLI---- 70 Query: 123 GQPWCFFPPSYPSYKLENLSSSEMGYTATLTRT-TPTFFPKDILTLRLDVMMETENRLHF 181 PWCFF ++ Y +++++++ +G A L R +PT F DI ++ +T NR F Sbjct: 71 --PWCFFVDNH-GYNVQDMTTTSIGVEAKLNRIPSPTLFGNDINSVLFTTQNQTPNRFRF 127 Query: 182 TIKDPANRRYEVPLETPHVHS--RAPSPLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPL 239 I DP NRRYEVP + + LY V+ ++ PF + V R+ +G+ L +T++ PL Sbjct: 128 KITDPNNRRYEVPHQYVKEFTGPTVSDTLYDVKVAQNPFSIQVIRKSNGKTLFDTSIGPL 187 Query: 240 FFADQFLQLSTSLPSQYITGLAEHLSP-LMLSTSWTRITLWNRDLAP-TPGANLYGSHPF 297 ++DQ+LQ+S LPS YI G+ E + SW ++ RD P NLYG F Sbjct: 188 VYSDQYLQISARLPSDYIYGIGEQVHKRFRHDLSWKTWPIFTRDQLPGDNNNNLYGHQTF 247 Query: 298 YLALED-GGSAHGVFLLNSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLD 356 ++ +ED G + GVFL+NSNAM++ +QP+P +++R TGGILD YI LG P+ VVQQY Sbjct: 248 FMCIEDTSGKSFGVFLMNSNAMEIFIQPTPIVTYRVTGGILDFYILLGDTPEQVVQQYQQ 307 Query: 357 VVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTF 416 +VG P MP YW LGF L RW Y S + ++VV A P D Q D+DYM+ ++DFT+ Sbjct: 308 LVGLPAMPAYWNLGFQLSRWNYKSLDVVKEVVRRNREAGIPFDTQVTDIDYMEDKKDFTY 367 Query: 417 NKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAG--SYRPYDEGLRRGVFITNETGQ 474 ++ F P VQ+LH G++Y++I+DPAIS A +Y Y+ G + V+I G Sbjct: 368 DQVAFNGLPQFVQDLHDHGQKYVIILDPAISIGRRANGTTYATYERGNTQHVWINESDGS 427 Query: 475 -PLIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGC 533 P+IG+VWPG T +PDFTNP + WW + + FH +V +DG+WIDMNE S+FI+GS GC Sbjct: 428 TPIIGEVWPGLTVYPDFTNPNCIDWWANECSIFHQEVQYDGLWIDMNEVSSFIQGSTKGC 487 Query: 534 PNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHRALVKAR-G 592 N+L PP+ P ++ + + TIC + Q Y++H+LYG + AIA+ +A+ K Sbjct: 488 NVNKLNYPPFTPDILDKLMYSKTICMDAVQNWGKQYDVHSLYGYSMAIATEQAVQKVFPN 547 Query: 593 TRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFLGN 652 R F+++RSTFAG GR+A HW GD +SWEQ+ S+ +L+F+L G+PLVGAD+CGF+ Sbjct: 548 KRSFILTRSTFAGSGRHAAHWLGDNTASWEQMEWSITGMLEFSLFGIPLVGADICGFVAE 607 Query: 653 TSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPA--QQAMRKALTLRYALLPHLY 710 T+EELC RW QLGAFYPF RNHNS Q+P F + + ++ R+ LT+RY LLP LY Sbjct: 608 TTEELCRRWMQLGAFYPFSRNHNSDGYEHQDPAFFGQNSLLVKSSRQYLTIRYTLLPFLY 667 Query: 711 TLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLG 770 TLF++AHV GETVARP+ EF +D+++W D + LWG ALLITPVL+ G V+ Y P Sbjct: 668 TLFYKAHVFGETVARPVLHEFYEDTNSWIEDTEFLWGPALLITPVLKQGADTVSAYIPDA 727 Query: 771 TWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPG 830 WYD + + + P Q V + P D I +HLR GYIIP+Q P Sbjct: 728 IWYDYE--------------SGAKRPW---RKQRVDMYLPADKIGLHLRGGYIIPIQEPD 770 Query: 831 LTTTESRQQPMALAVALTKGGEARGELFWDDGESLEVLERGAYTQVIFLARNNTIVNELV 890 +TTT SR+ P+ L VAL + A+G+ FWDDGE+ + ++ G Y F NNT+ ++V Sbjct: 771 VTTTASRKNPLGLIVALGENNTAKGDFFWDDGETKDTIQNGNYILYTFSVSNNTL--DIV 828 Query: 891 RVTS---EGAGLQLQKVTVLGVATAPQQ--VLSNGVPV---SNFTYSPDTKVLDIC-VSL 941 S EG L Q V +LG+ + + V N P+ SNFTY +VL I + L Sbjct: 829 CTHSSYQEGTTLAFQTVKILGLTDSVTEVRVAENNQPMNAHSNFTYDASNQVLLIADLKL 888 Query: 942 LMGEQFLVSW 951 +G F V W Sbjct: 889 NLGRNFSVQW 898 >3TOP-A nrPDB Length = 908 Score = 631 bits (1628), Expect = 0.0, Method: Compositional matrix adjust. Identities = 355/907 (39%), Positives = 495/907 (54%), Gaps = 85/907 (9%) Query: 89 RFDCAPDK-AITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFPPSYPSYKLENLSSSEMG 147 + DC PD+ + E C ARGC + + G P+C+F Y + ++ + G Sbjct: 12 KIDCYPDENGASAENCTARGCIWEASNSS------GVPFCYFVNDL--YSVSDVQYNSHG 63 Query: 148 YTATLTRTTPTF---FPKD-ILTLRLDVMMETENRLHFTIKDPANRRYEVP--LETPHVH 201 TA ++ + + FP + LRLDV L F I DP RYEVP L P + Sbjct: 64 ATADISLKSSVYANAFPSTPVNPLRLDVTYHKNEMLQFKIYDPNKNRYEVPVPLNIPSMP 123 Query: 202 SRAPS-PLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYITGL 260 S P LY V + PFG+ +RR+ G ++ ++ + F+D F+++ST LPS+Y+ G Sbjct: 124 SSTPEGQLYDVLIKKNPFGIEIRRKSTGTIIWDSQLLGFTFSDMFIRISTRLPSKYLYGF 183 Query: 261 AE--HLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAM 318 E H S W +++RD P N YG HP+Y+ LE+ GSAHGV LLNSNAM Sbjct: 184 GETEHRS-YRRDLEWHTWGMFSRDQPPGYKKNSYGVHPYYMGLEEDGSAHGVLLLNSNAM 242 Query: 319 DVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGY 378 DV QP PAL++R+TGG+LD Y+FLGP P+ V QQY +++G P M PYW LGF LCR+GY Sbjct: 243 DVTFQPLPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGY 302 Query: 379 SSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRY 438 + + + + M A P DVQ++D+DYM+ + DFT + F FPA++ + G R Sbjct: 303 QNDSEIASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPK-FAGFPALINRMKADGMRV 361 Query: 439 MMIVDPAISSSGPAGSYRPYDEGLRRGVFITN-ETGQPLIGKVWP--------------- 482 ++I+DPAIS + Y + G+ VFI G + GKVWP Sbjct: 362 ILILDPAISGN-ETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDS 420 Query: 483 ------GSTAFPDFTNPTALAWWEDMVAEFHDQ-------VPFDGMWIDMNEPSNFIRGS 529 AFPDF + WW+ + E ++ + FDGMWIDMNEPS+F+ G+ Sbjct: 421 QVELYRAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGA 480 Query: 530 ED-GCPNNELENPPYVPGVVGGT--LQAATICASSHQFL-----STHYNLHNLYGLTEAI 581 GC + L +PPY+P + L + T+C S Q L HYN+HNLYG ++ Sbjct: 481 VSPGCRDASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTR 540 Query: 582 ASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPL 641 ++ A+ + G R VI+RSTF GR+AGHW GD ++W+QL S+ +++F+L G+ Sbjct: 541 PTYEAVQEVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISY 600 Query: 642 VGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTL 701 GAD+CGF + E+CVRW QLGAFYPF RNHN++ + Q+P S+ R L Sbjct: 601 TGADICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDVAFVNISRTVLQT 660 Query: 702 RYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKA 761 RY LLP+LYTL H+AH G TV RPL EF D TW +D Q L G A L++PVL+ Sbjct: 661 RYTLLPYLYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNAR 720 Query: 762 EVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAG 821 VT YFP WYD T I++ G+W TLPAPLD IN+H+R G Sbjct: 721 NVTAYFPRARWYDYYT-----------------GVDINARGEWKTLPAPLDHINLHVRGG 763 Query: 822 YIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESLEVLERGAYTQVIFLAR 881 YI+P Q P L T SRQ+ M +AL G A G LFWDDG+S++ +G Y F A Sbjct: 764 YILPWQEPALNTHLSRQKFMGFKIALDDEGTAGGWLFWDDGQSIDTYGKGLYYLASFSAS 823 Query: 882 NNTIVNELV--RVTSEGAGLQLQKVTVLGVATAPQQVLSNGVPVS------NFTYSPDTK 933 NT+ + ++ + L+L + + GV + P V S + VS +F P T+ Sbjct: 824 QNTMQSHIIFNNYITGTNPLKLGYIEIWGVGSVP--VTSVSISVSGMVITPSFNNDPTTQ 881 Query: 934 VLDICVS 940 VL I V+ Sbjct: 882 VLSIDVT 888 >3WEN-A nrPDB Length = 913 Score = 554 bits (1427), Expect = e-158, Method: Compositional matrix adjust. Identities = 328/857 (38%), Positives = 455/857 (53%), Gaps = 92/857 (10%) Query: 137 KLENLSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLE 196 K++N + + L R +P + P DI L E ++ L I D NRR+E+P E Sbjct: 51 KVDNSTGKSLTALLQLIRNSPVYGP-DIQFLSFTASFEEDDTLRIRITDANNRRWEIPNE 109 Query: 197 -----------------------------TPHVHSRAPSPLYSVEFSEEPFGVIVRRQLD 227 T V S S L F PFG + R+ Sbjct: 110 VLPRPPPPPSPPPLSSLQHLPKPIPQNQPTTTVLSHPHSDLVFTLFHTTPFGFTIYRKST 169 Query: 228 GRVLLNTTVAP------LFFADQFLQLSTSLPSQ--YITGLAEHLSPLMLSTSWTRITLW 279 VL + T P L + DQ+LQLS+SLP+Q ++ GL EH P +TLW Sbjct: 170 HDVLFDATPIPSNPTTFLIYKDQYLQLSSSLPAQQAHLYGLGEHTKPTFQLAHNQILTLW 229 Query: 280 NRDLAP-TPGANLYGSHPFYLALEDG---GSAHGVFLLNSNAMDVVLQPSPALSWRSTGG 335 N D+A NLYGSHPFY+ + GS HGVFLLNSN MDV ++++ GG Sbjct: 230 NADIASFNRDLNLYGSHPFYMDVRSSPMVGSTHGVFLLNSNGMDVEYT-GDRITYKVIGG 288 Query: 336 ILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAH 395 I+D+YIF G P+ V+ QY ++G P PYW GFH CRWGY VV+ A Sbjct: 289 IIDLYIFAGRTPEMVLDQYTKLIGRPAPMPYWAFGFHQCRWGYRDVNEIETVVDKYAEAR 348 Query: 396 FPLDVQWNDLDYMDSRRDFTFNKDGF--RDFPAMVQELHQGGRRYMMIVDPAISSSGPAG 453 PL+V W D+DYMD+ +DFT + F V +LH+ G+RY+ I+DP I+++ Sbjct: 349 IPLEVMWTDIDYMDAFKDFTLDPVHFPLDKMQQFVTKLHRNGQRYVPILDPGINTN---K 405 Query: 454 SYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPFD 513 SY + G++ VFI + G P +G VWPG +PDF +P A ++W D + F D +P D Sbjct: 406 SYGTFIRGMQSNVFIKRD-GNPYLGSVWPGPVYYPDFLDPAARSFWVDEIKRFRDILPID 464 Query: 514 GMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGT--LQAATICASSHQFLS-THYN 570 G+WIDMNE SNFI + P + L+NPPY GG + + TI A++ + + T YN Sbjct: 465 GIWIDMNEASNFITSAP--TPGSTLDNPPYKINNSGGRVPINSKTIPATAMHYGNVTEYN 522 Query: 571 LHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPE 630 HNLYG E+ A+ ALV+ RPF++SRSTFAG G+Y HWTGD + W+ L S+P Sbjct: 523 AHNLYGFLESQATREALVRTSNERPFLLSRSTFAGSGKYTAHWTGDNAARWDDLQYSIPT 582 Query: 631 ILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEP 690 +L F L G+P++GAD+CGF +T+EELC RW QLGAFYPF R+H++ + QE Y + Sbjct: 583 MLNFGLFGMPMIGADICGFAESTTEELCRRWIQLGAFYPFSRDHSARDTTHQELYLWESV 642 Query: 691 AQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEAL 750 A A R L LRY LLP+ YTL + A++ G +ARPLF FP D +T+ + Q L G + Sbjct: 643 AASA-RTVLGLRYQLLPYYYTLMYDANLRGIPIARPLFFTFPDDVATYGISSQFLIGRGI 701 Query: 751 LITPVLQAGKAEVTGYFPLGTWYDL----QTVPVEALGSLPPPPAAPREPAIHSEGQWVT 806 +++PVLQ G V YFP G W+ L +V V A G +V+ Sbjct: 702 MVSPVLQPGAVSVNAYFPRGNWFSLFNYTSSVSVSA-------------------GTYVS 742 Query: 807 LPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESLE 866 L AP D INVH+ G I+ +QG +TT +R P L V ++ + GELF D+G ++ Sbjct: 743 LSAPPDHINVHIHEGNIVAMQGEAMTTQAARSTPFHLLVVMSDHVASTGELFLDNGIEMD 802 Query: 867 VLE-RGAYTQVIFLAR----NNTIVNELV-RVTSEGAGLQLQKVTVLGVATAPQQVLSNG 920 + G +T V F A N TI +E+V R + + K+T+LG L Sbjct: 803 IGGPGGKWTLVRFFAESGINNLTISSEVVNRGYAMSQRWVMDKITILG--------LKRR 854 Query: 921 VPVSNFTYSPDTKVLDI 937 V + +T D + I Sbjct: 855 VRIKEYTVQKDAGAIKI 871 >5HJR-A nrPDB Length = 857 Score = 340 bits (873), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 238/715 (33%), Positives = 349/715 (48%), Gaps = 80/715 (11%) Query: 248 LSTSLPS-QYITGLAEHLSPLMLSTS--WTRITLWNRDLAPTPGAN---LYGSHPFYLAL 301 L SLP +++ G+ EH L L + L+N D+ N LYGS P LA Sbjct: 178 LDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGSVPVLLA- 236 Query: 302 EDGGSAH---GVFLLNSNAMDVVLQ---PSPALSWRSTGGILDVYIFLGPEPKSVVQQYL 355 S H G+F LN+ V + P + W S GI+DV++ LGP V +QY Sbjct: 237 ---HSFHRDLGIFWLNAAETWVDISSNTPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYA 293 Query: 356 DVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFT 415 + G +PP + LG+H RW Y A +V + + P DV W D+++ D +R FT Sbjct: 294 SLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKRYFT 353 Query: 416 FNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQP 475 ++ F M++ L R+ + IVDP I YR ++E G+++ G Sbjct: 354 WDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDS---GYRVHEELRNHGLYVKTRDGSD 410 Query: 476 LIGKVWPGSTAFPDFTNPTALAWWEDMVA--EFHDQVPFDGMWIDMNEPSNFIRGSEDGC 533 G WPGS ++PDFTNP AWW +M + + P +W DMNEPS F Sbjct: 411 YEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVF-------- 462 Query: 534 PNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHRALVKARG- 592 N P + + + H H ++HN+YGL +A+ L++ G Sbjct: 463 ------NGP----------EVTMLKDAVHYGGWEHRDIHNIYGLYVHMATADGLIQRSGG 506 Query: 593 -TRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFLG 651 RPFV+SR+ F+G R+ WTGD + W+ L S+P L L+G+ GADV GF Sbjct: 507 IERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLSFCGADVGGFFK 566 Query: 652 NTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLRYALLPHLYT 711 N EL VRW Q+GA+ PF R H L + +EP+ + Q A+R AL RY+LLP YT Sbjct: 567 NPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIRDALFQRYSLLPFWYT 626 Query: 712 LFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFP--L 769 LF+QAH G V RPL++++P+D ST++++ Q + G+ALLI PV AG V Y P Sbjct: 627 LFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALLIHPVSDAGAHGVQVYLPGQE 686 Query: 770 GTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGP 829 WYD+Q+ H Q + LP L +I V R G I+P Sbjct: 687 EVWYDIQSY------------------QKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMR 728 Query: 830 GLTTTES-RQQPMALAVALTKGGEARGELFWDDGESLEVLERGAYTQVIFLARNNTIVNE 888 +++ + P+ L VAL+ G A+GELF DDG + R + L R + + Sbjct: 729 VRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEF----LLRRFSFSGST 784 Query: 889 LVRVTSEGAG-----LQLQKVTVLGVATAPQQVL-SNGVPVS--NFTYSPDTKVL 935 LV +++ G + +++V ++G VL + G P S +F + P+T VL Sbjct: 785 LVSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSPESRLSFQHDPETSVL 839 >5IEF-A nrPDB Length = 913 Score = 334 bits (857), Expect = 9e-92, Method: Compositional matrix adjust. Identities = 241/734 (32%), Positives = 349/734 (47%), Gaps = 99/734 (13%) Query: 248 LSTSLPS-QYITGLAEHLSPLMLSTS--WTRITLWNRDLAPTPGAN---LYGSHPFYLAL 301 L SLP +++ G+ EH L L + L+N D+ N LYGS P LA Sbjct: 214 LDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGSVPVLLA- 272 Query: 302 EDGGSAH---GVFLLN---------SNAMDVVL-------------QPSPALSWRSTGGI 336 S H G+F LN SN L P + W S GI Sbjct: 273 ---HSFHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMSESGI 329 Query: 337 LDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHF 396 +DV++ LGP V +QY + G +PP + LG+H RW Y A +V + + Sbjct: 330 IDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNM 389 Query: 397 PLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYR 456 P DV W D+++ D +R FT++ F M++ L R+ + IVDP I YR Sbjct: 390 PCDVIWLDIEHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDS---GYR 446 Query: 457 PYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVA--EFHDQVPFDG 514 ++E G+++ G G WPGS ++PDFTNP AWW +M + + P Sbjct: 447 VHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLY 506 Query: 515 MWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNL 574 +W DMNEPS F N P V + + H H ++HN+ Sbjct: 507 VWNDMNEPSVF--------------NGPEV----------TMLKDAVHYGGWEHRDIHNI 542 Query: 575 YGLTEAIASHRALVKARG--TRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEIL 632 YGL +A+ L++ G RPFV+SR+ F+G R+ WTGD + W+ L S+P L Sbjct: 543 YGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCL 602 Query: 633 QFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQ 692 L+G+ GADV GF N EL VRW Q+GA+ PF R H L + +EP+ + Q Sbjct: 603 SLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQ 662 Query: 693 QAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLI 752 A+R AL RY+LLP YTLF+QAH G V RPL++++P+D ST++++ Q + G+ALLI Sbjct: 663 DAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALLI 722 Query: 753 TPVLQAGKAEVTGYFP--LGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAP 810 PV AG V Y P WYD+Q+ H Q + LP Sbjct: 723 HPVSDAGAHGVQVYLPGQEEVWYDIQSY------------------QKHHGPQTLYLPVT 764 Query: 811 LDTINVHLRAGYIIPLQGPGLTTTES-RQQPMALAVALTKGGEARGELFWDDGESLEVLE 869 L +I V R G I+P +++ + P+ L VAL+ G A+GELF DDG + Sbjct: 765 LSSIPVFQRGGTIVPRWMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQT 824 Query: 870 RGAYTQVIFLARNNTIVNELVRVTSEGAG-----LQLQKVTVLGVATAPQQVL-SNGVPV 923 R + L R + + LV +++ G + +++V ++G VL + G P Sbjct: 825 RHEF----LLRRFSFSGSTLVSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSPE 880 Query: 924 S--NFTYSPDTKVL 935 S +F + P+T VL Sbjct: 881 SRLSFQHDPETSVL 894 >5DKX-A nrPDB Length = 951 Score = 312 bits (800), Expect = 4e-85, Method: Compositional matrix adjust. Identities = 219/710 (30%), Positives = 333/710 (46%), Gaps = 92/710 (12%) Query: 255 QYITGLAEHLSPLMLSTSWTR---------ITLWNRD----LAPTPGANLYGSHPFYLAL 301 +++ G+ H SPL L TR ++N D + +P LYGS PF A Sbjct: 243 EHVFGIPSHASPLSLKQ--TRGGEGNYNEPYRMYNADVFEYILDSP-MTLYGSIPFMQAH 299 Query: 302 EDGGSAHGVFLLNSN----------------AMDVVLQPSPALSWRSTGGILDVYIFLGP 345 S G+F LN+ A+ V + + W S G+LDV++FLGP Sbjct: 300 RKDSSV-GIFWLNAAETWVDITKGKDSKNPLALGVKSKITTRTHWFSESGLLDVFVFLGP 358 Query: 346 EPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDL 405 PK ++ +Y ++ G MP + LG+H CRW Y S + V M + + P DV W D+ Sbjct: 359 TPKDIISKYAELTGTTAMPQEFSLGYHQCRWNYVSDEDVKDVDRKMDKFNMPYDVIWLDI 418 Query: 406 DYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRG 465 +Y D ++ FT++K F+D M ++L GR+ + I+DP I ++ +Y DE + Sbjct: 419 EYTDEKKYFTWDKHSFKDPIGMGKQLEAHGRKLVTIIDPHIKNTN---NYPVVDELKSKD 475 Query: 466 VFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVA--EFHDQVPFDGMWIDMNEPS 523 + + + G G WPGS+ + D NP A WW+ + +F + +W DMNEPS Sbjct: 476 LAVKTKDGSIFEGWCWPGSSHWIDAFNPAAREWWKGLFKYDKFKGTMENTFIWNDMNEPS 535 Query: 524 NFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAIAS 583 F G E P + L H H ++HNL G+T A+ Sbjct: 536 VF-NGPEVTMPKDNL-----------------------HHGNWEHRDVHNLNGMTFQNAT 571 Query: 584 HRALVKAR---GTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVP 640 + AL+ + RPFV++R+ FAG R WTGD + W L +S+P +L + G P Sbjct: 572 YHALLSRKPGEHRRPFVLTRAFFAGSQRLGAMWTGDNTADWGYLKASIPMVLSQGIAGFP 631 Query: 641 LVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALT 700 GADV GF GN ++L RW Q G FYPF R H + + +EPY EP + AL Sbjct: 632 FAGADVGGFFGNPDKDLLTRWYQTGIFYPFFRAHAHIDARRREPYLTGEPYNTIIAAALR 691 Query: 701 LRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGE-ALLITPVLQAG 759 LRY+LLP YT F AH+ G + +P+F P + + +D Q G LL PV Sbjct: 692 LRYSLLPSWYTAFRHAHLDGTPIIKPMFYTHPSEEAGLPIDDQFFIGNTGLLAKPVTDKD 751 Query: 760 KAEVTGYFPLG-TWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHL 818 + V + P +YD T + + AA + A TL APL+ I + + Sbjct: 752 RTSVDIWIPDSEVYYDYFTYDIIS--------AAKSKTA--------TLDAPLEKIPLLM 795 Query: 819 RAGYIIPLQG-PGLTTTESRQQPMALAVALTKGGEARGELFWDDGESLEVLERGAYTQVI 877 R G++ + P ++ + P L V L +A G+L+ DDG+S + E+G Y Sbjct: 796 RGGHVFARRDIPRRSSALMKWDPYTLVVVLGNDRKAEGDLYVDDGDSFD-YEKGQYIHRR 854 Query: 878 FLARNNTIVN---ELVRVTSEGAGLQLQKVTVLGVATAPQQVLSNGVPVS 924 F+ NT+ + E S G L+K+ + V ++++ G P + Sbjct: 855 FIFDANTLTSADYEGRDDASIKEGEWLKKMRTVNV----EKIIVVGAPAA 900 >5DJW-A nrPDB Length = 697 Score = 304 bits (778), Expect = 1e-82, Method: Compositional matrix adjust. Identities = 200/612 (32%), Positives = 281/612 (45%), Gaps = 60/612 (9%) Query: 276 ITLWNRD---LAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAMDVVLQPSPALSWRS 332 I LWN D G LY SHP+ + + G+A G+ L ++ + + +S Sbjct: 81 IKLWNTDSGAYGVDKGTRLYQSHPWMMGVRKDGTAFGI-LFDTTWKAELSSTDEKIELKS 139 Query: 333 TGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMT 392 G V+I P++V++ ++ G M P W LG+ CR+ YS + ++ + Sbjct: 140 EGIPFRVFIIDRESPQAVIRGLSELTGTMPMIPRWALGYQQCRFSYSPDSRVIEIADTFR 199 Query: 393 RAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPA 452 P DV W D+DYMD R FTFN F + A+ ++LH G ++DP + P Sbjct: 200 LKRIPCDVIWMDIDYMDGYRIFTFNPKSFPNPKAVNRDLHIRGFHSAWMIDPG-AKVDP- 257 Query: 453 GSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPF 512 +Y Y G V++ G+ G WPG+ AFPDFT+P WW ++ +F Q Sbjct: 258 -NYFVYKSGTENDVWVKTADGKNFHGDAWPGAAAFPDFTSPKVNKWWRNLYKDFLAQ-GV 315 Query: 513 DGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLH 572 DG+W D+NEP + PN + G GG L A T H H Sbjct: 316 DGVWNDVNEPQ------INDTPNKTMPEDNLHRG--GGKLPAGT-----------HLQYH 356 Query: 573 NLYGLTEAIASHRALVKAR-GTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEI 631 N+YG AS ++ AR RPF+++RS F G RYA WTGD S W+ L SVP Sbjct: 357 NVYGFLMVKASREGILDARPEKRPFILTRSNFLGGQRYAATWTGDNGSCWDHLKMSVPMS 416 Query: 632 LQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPA 691 L L G P GAD+ GFL N +L W GAFYPF R H + +EP+ F + Sbjct: 417 LTLGLSGQPFSGADIGGFLFNADADLFGNWIGFGAFYPFARGHACAGTNNKEPWVFGQKV 476 Query: 692 QQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALL 751 + A R AL RY LLP+ YTL H+A G + RP+F PKD S + L G+ LL Sbjct: 477 EDASRIALERRYILLPYFYTLLHEASTNGMPIMRPVFFSDPKDLSLRAEEEAFLVGDNLL 536 Query: 752 ITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPL 811 I P A P G W +L V E + + Q Sbjct: 537 IIPAFANQPA-----LPKGIWKELSLV----------------EGDQNDKYQ-------- 567 Query: 812 DTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESLEVLERG 871 + +R G IIP TTE+ P+ L V L + G+A G ++WD G+ ++G Sbjct: 568 --AKMKIRGGAIIPTGKIIQNTTENSLDPLTLLVCLDEQGKASGNMYWDAGDGWS-YKKG 624 Query: 872 AYTQVIFLARNN 883 Y+ + F+A N Sbjct: 625 DYSLLQFVAERN 636 >2G3M-A nrPDB Length = 693 Score = 252 bits (643), Expect = 7e-67, Method: Compositional matrix adjust. Identities = 168/594 (28%), Positives = 285/594 (47%), Gaps = 51/594 (8%) Query: 254 SQYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGAN--LYGSHPFYLALEDGGSAHGVF 311 ++I GL E L R ++N D LY S P +++++DG A G F Sbjct: 61 KEHIIGLGE--KAFELDRKRKRYVMYNVDAGAYKKYQDPLYVSIPLFISVKDG-VATGYF 117 Query: 312 LLNSNAM--DVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGL 369 +++ + DV L+ + ++ Y+ GP + V+++Y ++ G PF+PP W Sbjct: 118 FNSASKVIFDVGLEEYDKVIVTIPEDSVEFYVIEGPRIEDVLEKYTELTGKPFLPPMWAF 177 Query: 370 GFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQ 429 G+ + R+ Y ++V+ M + F + + D+ YMDS + FT++ F + ++ Sbjct: 178 GYMISRYSYYPQDKVVELVDIMQKEGFRVAGVFLDIHYMDSYKLFTWHPYRFPEPKKLID 237 Query: 430 ELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPD 489 ELH+ + + IVD I +Y P+ G+ G F E+G+ +GK+WPG+T +PD Sbjct: 238 ELHKRNVKLITIVDHGIRVD---QNYSPFLSGM--GKFCEIESGELFVGKMWPGTTVYPD 292 Query: 490 FTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVG 549 F WW +++E+ Q DG+W+DMNEP++F R E + L P Sbjct: 293 FFREDTREWWAGLISEWLSQ-GVDGIWLDMNEPTDFSRAIEIRDVLSSL------PVQFR 345 Query: 550 GTLQAATICASSHQFLS----THYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAG 605 T + +L H + N Y L EA+A+ + + F++SR+ +AG Sbjct: 346 DDRLVTTFPDNVVHYLRGKRVKHEKVRNAYPLYEAMATFKGFRTSHRNEIFILSRAGYAG 405 Query: 606 HGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFLG------NTSEELCV 659 RYA WTGD SW+ L + +L ++ GVP VG D+ GF G + S +L V Sbjct: 406 IQRYAFIWTGDNTPSWDDLKLQLQLVLGLSISGVPFVGCDIGGFQGRNFAEIDNSMDLLV 465 Query: 660 RWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVA 719 ++ L F+PF R+H + + EP + ++ +++ + LRY LP++Y+L +A Sbjct: 466 KYYALALFFPFYRSHKATDGIDTEPVFLPDYYKEKVKEIVELRYKFLPYIYSLALEASEK 525 Query: 720 GETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVP 779 G V RPLF EF D + ++ + + G+ LL P++ ++ + P G WY+ Sbjct: 526 GHPVIRPLFYEFQDDDDMYRIEDEYMVGKYLLYAPIVSKEESRLVT-LPRGKWYNYWN-- 582 Query: 780 VEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTT 833 G + + + + H LP ++LR G IIPL+G L Sbjct: 583 ----GEIINGKSVVK--STHE------LP-------IYLREGSIIPLEGDELIV 617 >6JR6-A nrPDB Length = 838 Score = 244 bits (622), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 173/642 (26%), Positives = 280/642 (43%), Gaps = 90/642 (14%) Query: 278 LWNRDLAPTPGAN---LYGSHPFYLALEDGGSAHGVFLLNSNAMDVVL--QPSPALSWRS 332 +WN D P G N LY S PF+++ +G+F N+ + + + S+ + Sbjct: 177 MWNSD-QPCYGVNEDPLYKSIPFFMS----SYRYGIFFDNTYKTEFKFGSESNDYYSFEA 231 Query: 333 TGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMT 392 G + Y G + K ++Q Y+ + G P MPP W LGF CR Y+ R++ Sbjct: 232 PAGQMVYYFMFGNDYKEIIQNYIALTGKPIMPPKWALGFSQCRGDYTREDQAREIAAEFR 291 Query: 393 RAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPA 452 + P D+ + D+ + + +DF + K+ + + MV++L G + ++ DP IS + Sbjct: 292 KRKIPCDIIYQDIGWTEGLQDFDWRKNNYNNPKGMVKDLSDMGFKMIVSQDPVISQA--- 348 Query: 453 GSYRPYDEGLRRGVFITNETGQPLIGKVWP--GSTAFPDFTNPTALAWWEDMVAEFHDQV 510 + + + E G + + WP G+ DFT P WW + Q Sbjct: 349 -NQQQWKEADALGHLVKDVRTGKSYDMPWPWGGNCGVVDFTKPEVADWWGS-----YQQK 402 Query: 511 PFD----GMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLS 566 P + G W DM EP+ +ED A + L Sbjct: 403 PLNDGVRGFWTDMGEPA---WSNED-----------------------AVDRLNMKHHLG 436 Query: 567 THYNLHNLYGLT-EAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGD------VWS 619 H +HN+YG T + + + + R F ++R+ +AG RY W+GD V Sbjct: 437 MHNEIHNVYGFTWDKVVTEQFYKHNPNKRIFQMTRAAYAGLQRYTFGWSGDSGNGSNVLD 496 Query: 620 SWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTSE-----ELCVRWTQLGAFYPFMRNH 674 W+Q+A+ +P L + +P D+ G+ G+ + EL VRW Q G F P R H Sbjct: 497 GWKQMANQIPVGLSAGMGLIPFWTCDISGYCGDIKDYDAMAELYVRWLQFGVFTPLSRAH 556 Query: 675 NSLLSLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKD 734 + + EP+ F A+ RK++ L+Y L P+LYT +AH G + R L LE+P D Sbjct: 557 HEGGNAV-EPWKFGTEAENISRKSIELKYKLFPYLYTYAREAHDTGLPIMRALLLEYPND 615 Query: 735 SSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPR 794 T+ ++ Q L G+ LL+ PV++ G Y P G W D + G Sbjct: 616 KETFKLNGQFLVGKELLVAPVVEQGAVTKDVYLPEGEWIDFNNCKTKYKGE--------- 666 Query: 795 EPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAV---ALTKGG 851 QW+T+ APL+TI V ++ G IIP E + P+ + L K Sbjct: 667 --------QWITVDAPLNTIPVFVKKGSIIPQMPVMQYIDEKKVYPVTFDIFPGNLNK-- 716 Query: 852 EARGELFWDDGESLEVLERGAYTQVIFLARNNTIVNELVRVT 893 E + DDGES + ER + + ++ + NE +++T Sbjct: 717 ETSFTFYEDDGESRD-YERDVFCKTKITSKAS---NEEIKIT 754 >3POC-A nrPDB Length = 666 Score = 238 bits (607), Expect = 9e-63, Method: Compositional matrix adjust. Identities = 157/573 (27%), Positives = 256/573 (44%), Gaps = 42/573 (7%) Query: 290 NLYGSHPFYLALEDGGSAHGVFLLNSNAM--DVVLQPSPALSWRSTGGILDVYIFLGPEP 347 +LYG+H F + G + G+F + + D+ L LD+Y+ G Sbjct: 86 SLYGAHNFIIV--SGKTTFGLFFDYPSKLTFDIGYTRMDTLKVSCENADLDIYVIEGENA 143 Query: 348 KSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDY 407 +V+Q+ V+G ++PP + GF RWGY++ R V + H P+D+ + D+DY Sbjct: 144 YDIVKQFRRVIGRSYIPPKFAFGFGQSRWGYTTKEDFRAVAKGYRENHIPIDMIYMDIDY 203 Query: 408 MDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVF 467 M +DFT N+ F DFP V+E+ R + I+D + Y Y+EG++ F Sbjct: 204 MQDFKDFTVNEKNFPDFPEFVKEMKDQELRLIPIIDAGVKVE---KGYEVYEEGVKNNYF 260 Query: 468 ITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIR 527 E G + VWPG T FPD NP A W+ D DQ +G W MNEP+ F Sbjct: 261 CKREDGSDFVAAVWPGDTHFPDMLNPEARKWFGDKYRFLIDQ-GIEGFWNAMNEPAIFY- 318 Query: 528 GSEDGCPNNELENPPYVPGVVGG----TLQA--ATICASSHQFLSTHYN----------L 571 S +G + + G +QA I S + ++N + Sbjct: 319 -SSEGLAEAKEFAGEFAKDTEGKIHPWAMQAKMKDIVNSPEDYKRFYHNVNGKKIRHDKV 377 Query: 572 HNLYGLTEAIASHRALVKARGTRPFVI-SRSTFAGHGRYAGHWTGDVWSSWEQLASSVPE 630 HNL+G A+ A + + F++ SRS++ G RY G W GD S W + ++ Sbjct: 378 HNLFGYNMTRAAGEAFERIDPEKRFLMFSRSSYIGMHRYGGIWMGDNKSWWSHILLNLKM 437 Query: 631 ILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEP 690 + N+ G GAD+ GF +T+ +L +R+ LG F P MR+H + + QE Y F Sbjct: 438 LPSLNMCGFMYTGADLGGFGDDTTRDLLLRFLALGVFTPLMRDHAAEGTREQECYQFENI 497 Query: 691 AQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEAL 750 + R + RY L+P+LY+ + +A + + +PL +P D V+ QL+ G + Sbjct: 498 --EDFRSVINARYRLVPYLYSEYMKAALNDDMYFKPLGFVYPDDKMAIRVEDQLMLGNEI 555 Query: 751 LITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAP 810 +I PV + Y P +++ + GS+ E +H + Sbjct: 556 MIAPVYEQNARGRYVYLPE----EMKFIKFMPDGSISEEVL---EKGVH------YVDVA 602 Query: 811 LDTINVHLRAGYIIPLQGPGLTTTESRQQPMAL 843 L+ + + +R+G IP+ + + M L Sbjct: 603 LNEVPLFIRSGKCIPVAEAAECVKDIDTENMQL 635 >5I24-A nrPDB Length = 836 Score = 192 bits (488), Expect = 6e-49, Method: Compositional matrix adjust. Identities = 164/615 (26%), Positives = 264/615 (42%), Gaps = 72/615 (11%) Query: 315 SNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLC 374 S AMD+ S L + G + G S+++ + V G +PP W LG Sbjct: 187 SGAMDIGKTESDILQLEAKSGRSAYILVAGNSYPSLIENFTQVTGRQPLPPRWALGSFAS 246 Query: 375 RWGYSSTAITRQVVENMTRAHFPLD-----VQWNDLDYMDSRRDFTFNKDGFRDFPAMVQ 429 R+GY S A TR V+ FPLD + W D + ++K+ F M+ Sbjct: 247 RFGYRSEAETRATVQKYKTEDFPLDTIVLDLYWFGKDIKGHMGNLDWDKENFPTPLDMMA 306 Query: 430 ELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPD 489 + Q G + ++I +P + +S + +D+ ++ + GQP +++ G+ D Sbjct: 307 DFKQQGVKTVLITEPFVLTSS-----KRWDDAVKAKALAKDPQGQPKAFELYFGNGGIID 361 Query: 490 FTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVG 549 + W+ + + Q G W D+ EP +P +G Sbjct: 362 VFSKEGSRWFSSIYKDLSKQ-GVAGWWGDLGEPEM---------------HPEDTQHAIG 405 Query: 550 GTLQAATICASSHQFLSTHYNLHNLYGLTEA-IASHRALVKARGTRPFVISRSTFAGHGR 608 A T+ HN YG A + + L + RPF++ R+ F G R Sbjct: 406 ---DADTV--------------HNAYGHRWAEMLYQQQLDQFPELRPFIMMRAGFVGSQR 448 Query: 609 YAGH-WTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFL-GNT-SEELCVRWTQLG 665 Y WTGDV +W LAS V LQ +LLG + +D+ GF G T +E+ +RW Q G Sbjct: 449 YGMIPWTGDVSRTWGGLASQVELALQMSLLGFGYIHSDLGGFADGETLDKEMYIRWLQYG 508 Query: 666 AFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVAR 725 F P R H +P EP E + +R + LRY +LP++YT +Q + G + R Sbjct: 509 VFQPVYRPHGQD-HIPSEPVFQDEETKAILRPLVKLRYRMLPYIYTAAYQNTLTGMPLMR 567 Query: 726 PLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGS 785 PLF K+ + WG++LL+TP+ QAG V+ P G W+D Sbjct: 568 PLFFSDEKNPALIDNKTSYFWGDSLLVTPITQAGVESVSIPAPKGVWFDFW--------- 618 Query: 786 LPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAV 845 ++ ++G +TLP L TI V ++AG +P P ++TTE + +L + Sbjct: 619 --------KDTRYQTDGAPLTLPTDLHTIPVLVKAGAFMPYV-PAVSTTEDYRSD-SLEI 668 Query: 846 ALTKGGE---ARGELFWDDGESLEVLERGAYTQVIFLA--RNNTIVNELVRVTSEGAGLQ 900 A+GE+F DDG+ ++R + + A +N + +L R G+ Sbjct: 669 HYYADASVPLAQGEIFEDDGKDPNSIKRNQFDLLTLQATHTDNQLHFQLARTGKGYRGMP 728 Query: 901 LQKVTVLGVATAPQQ 915 ++ T L + A Q Sbjct: 729 ERRATTLVIHNASDQ 743 >5JOV-A nrPDB Length = 955 Score = 141 bits (356), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 146/584 (25%), Positives = 227/584 (38%), Gaps = 95/584 (16%) Query: 330 WRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVE 389 W LD Y G V+ Y + G + P W +GF R Y++ ++ Sbjct: 368 WSEMTKQLDYYFMAGENMDDVISGYRSLTGKSPVMPKWAMGFWQSREKYNTQEEMLGALK 427 Query: 390 NMTRAHFPLD---VQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAI 446 PLD + WN ++ F+K F D AMV +H R M+ V P Sbjct: 428 GFRDRKIPLDNIVLDWNHWP-ENAWGSHEFDKARFPDPKAMVDSIHAMHARMMISVWPKF 486 Query: 447 SSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPG-STAFPDFTNPTALA-WWEDMVA 504 + ++ +DE G L V PG F D +P A +W+ M Sbjct: 487 YVT--TEHFKEFDE---NGWMYQQSVKDSLKDWVGPGYHYGFYDAYDPDARKLFWKQMYE 541 Query: 505 EFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQF 564 ++ + D W+D +EP+ +R C + E L T SS +F Sbjct: 542 HYY-PLGIDAWWMDASEPN--VRD----CTDLEYRK----------ALCGPTALGSSTEF 584 Query: 565 LSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYA-GHWTGDVWSSWEQ 623 + Y L N EAI + V R F+++RS FAG RY+ W+GD+ + WE Sbjct: 585 FNA-YALMN----AEAIYDGQRGVD-NNKRVFLLTRSGFAGLQRYSTATWSGDIGTRWED 638 Query: 624 LASSVPEILQFNLLGVPLVGADVCGFLGNTS---------------------EELCVRWT 662 + + + L F + G+P D+ GF EL RW Sbjct: 639 MKAQISAGLNFAMSGIPYWTMDIGGFCVENRYVAGQKQWNATKTENADYKEWRELNTRWY 698 Query: 663 QLGAFYPFMRNHNSLLSLPQEPYSFSE---------PAQQAMRKALTLRYALLPHLYTLF 713 Q GAF P R H Y F E PA Q++ LRY ++P++Y+L Sbjct: 699 QFGAFVPLYRAHGQ--------YPFREIWEIAPEGHPAYQSVVYYTKLRYNMMPYIYSLA 750 Query: 714 HQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGT-W 772 T+ RPL ++F D+ + Q ++G + +++PV + G YFP W Sbjct: 751 GMTWFDDYTIMRPLVMDFTADAEVNDIGDQFMFGPSFMVSPVYRYGDRSREIYFPQAEGW 810 Query: 773 YDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLT 832 YD + +A G + AP + I +++RAG IIP Sbjct: 811 YDFYSGKFQAGGERK------------------VIEAPYERIPLYVRAGAIIPFGDDIQY 852 Query: 833 TTESRQQPMALAVALTKGGEARGELFWDDGESLEVLERGAYTQV 876 T E + + L + +G + L+ D+G + E+G Y + Sbjct: 853 TDEKPAEHIRLYI--YQGADGEFTLYEDEGVNYN-YEQGMYAMI 893 >5F7C-A nrPDB Length = 761 Score = 136 bits (342), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 141/621 (22%), Positives = 243/621 (39%), Gaps = 84/621 (13%) Query: 251 SLPSQYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGV 310 S P + G E + LS + L N+D Y + PFYL+ +G Sbjct: 198 SRPDECFAGTGERFFKMDLSGQ--TLFLKNQDGQGVNNRRTYKNIPFYLS----SRMYGT 251 Query: 311 FL--LNSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWG 368 F + + + + ++ + S +LD ++ G + +++ Y D+ GYP MPP W Sbjct: 252 FYHTCAHSKLSLAGHSTRSVQFLSDQAMLDAFVIAGDTMEEILRGYRDLTGYPSMPPLWS 311 Query: 369 LGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYM--DSRRDFTFNKDGFRDFPA 426 G + R Y S ++ + M H+P DV D + D ++ FN++ F D Sbjct: 312 FGVWMSRMTYFSADEVNEICDRMRAEHYPCDVIHLDTGWFRTDWLCEWKFNEERFPDPKG 371 Query: 427 MVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTA 486 +Q L + G R + P ++ +E + + G + G+ Sbjct: 372 FIQRLKKNGYRVSLWQLPYVAEDAEQIEEAKANEYIAPLTKQQDTDGSNFSALDYAGTI- 430 Query: 487 FPDFTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPG 546 DFT P A W++ ++ + +DM C + ++ Sbjct: 431 --DFTYPKATEWYKGLLKQL----------LDMGVT----------CIKTDFGENIHMDA 468 Query: 547 VVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGH 606 V G + + Y + K V +R+ +AG Sbjct: 469 VYKGMKPELLNNLYALLYQKAAYEI----------------TKEVTGDGIVWARAAWAGC 512 Query: 607 GRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGF--LGN-----TSEELCV 659 RY HW GD SSW+ +A S+ L F L G DV GF L N +E++ + Sbjct: 513 QRYPLHWGGDSCSSWDGMAGSLKGGLHFGLSGFAFWSHDVPGFHTLPNFMNSIVAEDVYM 572 Query: 660 RWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVA 719 RWTQ G F +R H + +EP+ + A ++K LRY+L+P++ A + Sbjct: 573 RWTQFGVFTSHIRYHG---TNKREPWHYPAIA-PLVKKWWKLRYSLIPYIIEQSKLAVES 628 Query: 720 GETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVP 779 G + + L L P+D W +D + +G L+ PV+ + Y P G W + T Sbjct: 629 GWPLLQALILHHPEDKLCWHIDDEYYFGNDFLVAPVMNSENRRDI-YLPEGQWVNFFT-- 685 Query: 780 VEALGSLPPPPAAPREPAIHSEGQWVT-LPAPLDTINVHLRAGYIIPLQGPGLTTTESRQ 838 E L G+W+ + PL+ + V++R +IP+ + T+ + Sbjct: 686 GERLQG----------------GRWLKEVYVPLEEMPVYVRENAVIPIYPEEVNCTD--E 727 Query: 839 QPMALAVALTKGGEARGELFW 859 + ++AL +G FW Sbjct: 728 MDLGKSIALRIDHNYKG--FW 746 >1XSK-A nrPDB Length = 778 Score = 130 bits (328), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 117/538 (21%), Positives = 207/538 (38%), Gaps = 80/538 (14%) Query: 257 ITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSN 316 + GL E + L+ + + WNRD T Y + PFY+ +GV + + Sbjct: 162 VYGLGERFTALVRNGQ--TVETWNRD-GGTSTEQAYKNIPFYMT----NRGYGVLVNHPQ 214 Query: 317 --AMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLC 374 + +V + + + L+ ++ GP PK+V+ +Y G P +PP W G L Sbjct: 215 CVSFEVGSEKVSKVQFSVESEYLEYFVIDGPTPKAVLDRYTRFTGRPALPPAWSFGLWLT 274 Query: 375 RWGYSST---AITRQVVENMTRAHFPLDVQWNDLDYMDSRR--DFTFNKDGFRDFPAMVQ 429 +++ A ++ M + PL V D +M + + DF ++ F D M++ Sbjct: 275 T-SFTTNYDEATVNSFIDGMAERNLPLHVFHFDCFWMKAFQWCDFEWDPLTFPDPEGMIR 333 Query: 430 ELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPD 489 L G + + ++P I P + E +G + G W A D Sbjct: 334 RLKAKGLKICVWINPYIGQKSPV-----FKELQEKGYLLKRPDGSLWQWDKWQPGLAIYD 388 Query: 490 FTNPTALAWWEDMV------------AEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNE 537 FTNP A W+ D + +F +++P D W D ++P Sbjct: 389 FTNPDACKWYADKLKGLVAMGVDCFKTDFGERIPTDVQWFDGSDPQKM------------ 436 Query: 538 LENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFV 597 H + YN L + + A+ + Sbjct: 437 ------------------------HNHYAYIYNELVWNVLKDTVGEEEAV---------L 463 Query: 598 ISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTSEEL 657 +RS G ++ HW GD ++++E +A S+ L L G D+ GF + Sbjct: 464 FARSASVGAQKFPVHWGGDCYANYESMAESLRGGLSIGLSGFGFWSHDIGGFENTAPAHV 523 Query: 658 CVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAH 717 RW G R H S + P+++ + + +R L+ ++P+LY +A+ Sbjct: 524 YKRWCAFGLLSSHSRLHGS--KSYRVPWAYDDESCDVVRFFTQLKCRMMPYLYREAARAN 581 Query: 718 VAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDL 775 G + R + +EFP D + +D Q + G+ +++ PV +V Y P G W L Sbjct: 582 ARGTPMMRAMMMEFPDDPACDYLDRQYMLGDNVMVAPVFTEA-GDVQFYLPEGRWTHL 638 >5I0E-B nrPDB Length = 733 Score = 103 bits (257), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 116/476 (24%), Positives = 180/476 (37%), Gaps = 71/476 (14%) Query: 347 PKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDV----QW 402 P V+ +LDV G P P W G +++ ++ + ++ P+ V W Sbjct: 273 PTDVLNGFLDVAGRPAEMPEWIFGLWASGNEWNTQSLVMEQMDRHRNEGIPVSVVVIEAW 332 Query: 403 NDLD----YMDSRR-----------DFTFNKDGFRDFPA-MVQELHQGGRRYMMIVDPAI 446 +D + + D+R DFT+ DG PA M++ELH+ G R ++ P Sbjct: 333 SDEEGFTIFRDARYVPNQGQPHRGPDFTYPSDGAWPDPAGMIRELHERGIRVILWQIPLQ 392 Query: 447 SSSGPAG--SYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAF-PDFTNPTALAWWEDMV 503 + G + + + G + G P + W A PD + WW + Sbjct: 393 KTDDDLGPEALAQGNALIASGHVVKEPDGTPYKNRGWWFPNALMPDLSTEAGRQWWTEQR 452 Query: 504 AEFHDQVPFDGMWIDMNEPS--NFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASS 561 + + DG D E + + +R EDG +E Sbjct: 453 RYLVEDLDIDGFKTDGGEHAWGSDLR-YEDGRRGDEG----------------------- 488 Query: 562 HQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSW 621 +NLY + A A + L+++ G P SRS F G + +W GD S+W Sbjct: 489 ----------NNLYPVNYARA-YGDLLRSAGKYPVTFSRSGFTGSQAHGLYWAGDEDSTW 537 Query: 622 EQLASSVPEILQFNLLGVPLVGADVCGFLGNTSE-ELCVRWTQLGAFYPFMR-----NHN 675 E SS+ + G+ G D+ GF G E EL R F P M+ +H+ Sbjct: 538 EAFRSSITAGITAGACGILYWGWDLAGFSGPVPEAELYARAFAAATFMPIMQYHSEFHHH 597 Query: 676 SLLSLPQEPYSFSEPAQ-----QAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLE 730 L + P++ +E R +R AL P+L Q G+ + R +F + Sbjct: 598 ELPLRDRTPWNVAEQTGCGELIDLARHYTRVREALRPYLVAQTRQCLQTGKPLMRAMFYD 657 Query: 731 FPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSL 786 D W Q + G+ LLI PV G T Y P G W D + V G L Sbjct: 658 HADDPEIWAHPRQYMLGDELLINPVTAPGATTWTTYLPEGQWEDYWSGEVSEGGHL 713 >5X3I-A nrPDB Length = 743 Score = 96.3 bits (238), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 120/480 (25%), Positives = 179/480 (37%), Gaps = 76/480 (15%) Query: 336 ILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAH 395 ++D+ I+ G +P +V+ +LD VG P W F L W + T+Q+V H Sbjct: 267 VVDLAIYEG-DPATVLTGFLDEVGRAEELPGWV--FRL--WASGNEWNTQQLVTARMDTH 321 Query: 396 FPLDVQ-----------------WNDLDYMDSR-------RDFTFNKDG-FRDFPAMVQE 430 L + W D Y + DF++ DG + D AM+ E Sbjct: 322 RDLAIPVGAVVIEAWSDEQGITIWRDAVYAVTEDGSAHRAEDFSYRPDGAWPDPKAMIDE 381 Query: 431 LHQGGRRYMMIVDPAISSSGPAGSYRPYDEGL-RRGVFITNETGQPLIGKVWPGSTAF-P 488 LH G + ++ P + G + R G + G + W A P Sbjct: 382 LHARGIKVILWQIPLQKTEFSTGQVAADAAAMVRDGHAVLEADGTAYRNRGWWFPQALMP 441 Query: 489 DFTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVV 548 D + WW + + DG G E ++ + Y G Sbjct: 442 DLSVQRTRDWWTEKRRYLVEHFDVDGF---------KTAGGEHAWGHDLV----YADGRK 488 Query: 549 GGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGR 608 G +NLY + A A L+++ G P SR+ F G Sbjct: 489 GD-------------------EGNNLYPVHYARA-FGDLLRSAGKAPVTFSRAGFTGSQA 528 Query: 609 YAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTSE-ELCVRWTQLGAF 667 + W GD S+W+ SSV L G+ G D+ GF G + EL +R AF Sbjct: 529 HGIFWAGDEDSTWQAFRSSVTAGLTAASCGIVYWGWDLAGFSGPVPDAELYLRAAAASAF 588 Query: 668 YPFMR-----NHNSLLSLPQEPYSFSEPAQQA-----MRKALTLRYALLPHLYTLFHQAH 717 P M+ NH+ L + P+ +E R+ TLR +L+P+L + Sbjct: 589 MPIMQYHSEFNHHQLPLRDRTPWHVAETTGDDRVVPLFRRFATLRESLVPYLTEQAARTI 648 Query: 718 VAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQT 777 + RPLF + D W +Q L G+ LLI PVL+ G T Y P G W D+ T Sbjct: 649 ATDRPLMRPLFFDHENDPEIWNHPYQYLLGDELLINPVLEPGATTWTTYLPAGEWIDVWT 708 >5AEG-A nrPDB Length = 686 Score = 91.7 bits (226), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 102/450 (22%), Positives = 175/450 (38%), Gaps = 62/450 (13%) Query: 377 GYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGR 436 G I Q + F V WN + +N + + + +++ +Q G Sbjct: 279 GVKVNGIWAQDWSGIRMTSFGKRVMWN----------WKWNSENYPQLDSRIKQWNQEGV 328 Query: 437 RYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTAL 496 +++ ++P ++S +E + G + +G + + D TNP A Sbjct: 329 QFLAYINPYVASDKDLC-----EEAAQHGYLAKDASGGDYLVEFGEFYGGVVDLTNPEAY 383 Query: 497 AWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAAT 556 AW+++++ + N I E GC + Y+P Sbjct: 384 AWFKEVIKK------------------NMI---ELGCGGWMADFGEYLP----------- 411 Query: 557 ICASSHQFLSTHYNLHNLYGLTEAIASHRALVK-ARGTRPFVISRSTFAGHGRYAGH-WT 614 H +S +HN + A ++ AL + + R+ G +Y+ W Sbjct: 412 TDTYLHNGVSAEI-MHNAWPALWAKCNYEALEETGKLGEILFFMRAGSTGSQKYSTMMWA 470 Query: 615 GDV---WSSWEQLASSVPEILQFNLLGVPLVGADVCG----FLGNTSEELCVRWTQLGAF 667 GD WS + LAS VP L + G L +D+ G F S+EL +RW AF Sbjct: 471 GDQNVDWSLDDGLASVVPAALSLAMTGHGLHHSDIGGYTTLFEMKRSKELLLRWCDFSAF 530 Query: 668 YPFMRNHNSLLSLPQEPYSFSEPAQQAMR--KALTLRYALLPHLYTLFHQAHVAGETVAR 725 P MR H + P + + F A+ + T+ L P+L +G V R Sbjct: 531 TPMMRTHEG--NRPGDNWQFDGDAETIAHFARMTTVFTTLKPYLKEAVALNAKSGLPVMR 588 Query: 726 PLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGS 785 PLFL + D+ T+T+ +Q L G +L+ PV + G+++ T Y P W T G Sbjct: 589 PLFLHYEDDAHTYTLKYQYLLGRDILVAPVHEEGRSDWTLYLPEDNWVHAWTGEAFRGGE 648 Query: 786 LPPPPAAPREPAIH-SEGQWVTLPAPLDTI 814 + + P + ++ +W L A L +I Sbjct: 649 VTVNAPIGKPPVFYRADSEWAALFASLKSI 678 >6DRU-A nrPDB Length = 718 Score = 85.1 bits (209), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 74/309 (23%), Positives = 120/309 (38%), Gaps = 36/309 (11%) Query: 489 DFTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVV 548 D TNP+A + M+ + + WID + E+ + +E+ P+ Sbjct: 366 DSTNPSARKFLWSMLKKNYYDKGIKNFWIDQADGGALGEAYENNGQSTYIESIPF----- 420 Query: 549 GGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGR 608 TL A + + Y + + E + + +SRS + G R Sbjct: 421 --TLPNVNYAAGTQLSVGKLYPWAHQQAIEEGFRNATDTKEGSACDHVSLSRSGYIGSQR 478 Query: 609 YAGH-WTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTS------------E 655 + W+GD S W+ LA V L G D GF +++ Sbjct: 479 FCSMIWSGDTTSVWDTLAVQVASGLSAAATGWGWWTVDAGGFEVDSTVWWSGNIDTPEYR 538 Query: 656 ELCVRWTQLGAFYPFMRNHNS-------LLSLPQEPYSFSEPAQQAMRKALTLRYALLPH 708 EL VRW F PFMR H S + EP+S+ + + LRY L + Sbjct: 539 ELYVRWLAWTTFLPFMRTHGSRTCYFQDAYTCANEPWSYGASNTPIIVSYIHLRYQLGAY 598 Query: 709 LYTLFHQAHVAGETVARPLFLEFPK---------DSSTWTVDHQLLWGEALLITPVLQAG 759 L ++F+Q H+ G ++ RPL+++F K S++ Q ++G LL++PV Sbjct: 599 LKSIFNQFHLTGRSIMRPLYMDFEKTDPKISQLVSSNSNYTTQQYMFGPRLLVSPVTLPN 658 Query: 760 KAEVTGYFP 768 E Y P Sbjct: 659 VTEWPVYLP 667 >5OHS-A nrPDB Length = 672 Score = 69.7 bits (169), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 53/186 (28%), Positives = 82/186 (44%), Gaps = 5/186 (2%) Query: 618 WSSWEQLASSVPEILQFNLLGVPLVGADVCGF---LGNT-SEELCVRWTQLGAFYPFMRN 673 +S + L + + L L+G +D+ G+ GN + EL +RWT++ AF P MR Sbjct: 460 FSRHDGLVTVICGALSSGLMGNAYHHSDIGGYTSLFGNVRTAELIMRWTEMAAFTPVMRT 519 Query: 674 HNSLLSLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPK 733 H E + + AL P+L +L +A G V RPLFL + Sbjct: 520 HEGNRPRDNLQIDQDETVLAHFARMTAIYVALAPYLKSLSAEAAKTGLPVQRPLFLHYEN 579 Query: 734 DSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFP-LGTWYDLQTVPVEALGSLPPPPAA 792 + T+ V L+G +L+ PV +AG+ + + Y P G W L + A G Sbjct: 580 EPQTYAVQDCYLYGADMLVAPVWKAGETQRSLYLPGHGEWVHLWSGKRHAGGRDITVETP 639 Query: 793 PREPAI 798 EPA+ Sbjct: 640 LGEPAV 645 >4XPS-A nrPDB Length = 720 Score = 52.4 bits (124), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 49/212 (23%), Positives = 88/212 (41%), Gaps = 42/212 (19%) Query: 683 EPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLE--FPKDS----- 735 +P+S+ E + ++K LR ++P+ Y+ F + H G R + LE F +D+ Sbjct: 492 KPWSYPE-VEADVKKFALLRMQMMPYWYSAFARYHFEGMPPFRGMGLEEGFRQDAKVEKL 550 Query: 736 -------------STWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPVEA 782 ++ + Q + G+ LL+ P+ AG+ P G WYD T Sbjct: 551 NKVNLEENPYAEAASKEIKDQYMAGDDLLVAPMF-AGEKSRKVVLPKGKWYDFYT----- 604 Query: 783 LGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMA 842 +G+ + + LD I V++R G I+P+ P L + Q + Sbjct: 605 -------------GEYAGDGEVLDVTPGLDKIPVYVRDGGIVPMM-PALLNSPKSNQKVD 650 Query: 843 LAVALTKGGEARGELFWDDGESLEVLERGAYT 874 L + +L+ DDGE+ E+G ++ Sbjct: 651 LEIRYYGNKPGEFKLYDDDGETFN-YEKGDFS 681 Score = 50.4 bits (119), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 33/121 (27%), Positives = 60/121 (49%), Gaps = 10/121 (8%) Query: 337 LDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGF-HLCRWGYSSTAITRQVVENMTRAH 395 ++VY+F GP+P V++Y + G ++PP WGLGF Y+ + ++ V + Sbjct: 200 VEVYVFGGPKPIDAVKRYNLLNGGGYLPPRWGLGFTQRVMTRYTDKDVEKE-VNDFKEKG 258 Query: 396 FPLDV-----QWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSG 450 +PLD W Y + F+++K + D + V+++ G R + ++P IS Sbjct: 259 YPLDFVGLEPGWQSKAYPGT---FSWDKSRYPDPTSFVKKMKDQGIRLNLWINPYISPDA 315 Query: 451 P 451 P Sbjct: 316 P 316 >1HI7-A nrPDB Length = 60 Score = 37.7 bits (86), Expect = 0.025, Method: Composition-based stats. Identities = 17/49 (34%), Positives = 24/49 (48%), Gaps = 8/49 (16%) Query: 82 CDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFP 130 C V P R +C +T QC +GCC+ +G+ PWCF+P Sbjct: 7 CTVAPRERQNCG-FPGVTPSQCANKGCCFDDTVRGV-------PWCFYP 47 >1PSP-A nrPDB Length = 106 Score = 33.5 bits (75), Expect = 0.44, Method: Composition-based stats. Identities = 24/97 (24%), Positives = 37/97 (38%), Gaps = 26/97 (26%) Query: 86 PNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFP-PS------------ 132 P +R +C IT +QC GCC+ G+ PWCF P P+ Sbjct: 13 PKNRVNCG-FPGITSDQCFTSGCCFDSQVPGV-------PWCFKPLPAQESEECVMQVSA 64 Query: 133 -----YPSYKLENLSSSEMGYTATLTRTTPTFFPKDI 164 YP E+ ++ ++ T+ FFP + Sbjct: 65 RKNCGYPGISPEDCAARNCCFSDTIPEVPWCFFPMSV 101 >1L5X-A nrPDB Length = 280 Score = 31.6 bits (70), Expect = 1.8, Method: Compositional matrix adjust. Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 10/73 (13%) Query: 247 QLSTSLPSQYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGS 306 +L + +Y + E + P + W L+ RDLAP P ++Y + L++GG Sbjct: 183 KLVKAAKLRYAQQVVERVDPRGVRYYW----LYGRDLAPEPETDVY------VVLKEGGI 232 Query: 307 AHGVFLLNSNAMD 319 A LN NA+D Sbjct: 233 AITPLTLNLNAVD 245 >5YYS-A nrPDB Length = 949 Score = 30.4 bits (67), Expect = 3.7, Method: Compositional matrix adjust. Identities = 16/48 (33%), Positives = 28/48 (58%), Gaps = 3/48 (6%) Query: 459 DEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVAEF 506 +E ++RG F+ E G+ L+GK W + A TNP A+ D++ ++ Sbjct: 847 NEAIQRGSFV--EFGR-LVGKTWEQNKALDSGTNPPAVEAIIDLIKDY 891 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5KZW-A nrPDB 1290 0.0 3LPO-A nrPDB 1065 0.0 3L4Y-A nrPDB 1037 0.0 3TOP-A nrPDB 949 0.0 3WEN-A nrPDB 876 0.0 5HJR-A nrPDB 706 0.0 5IEF-A nrPDB 700 0.0 5DKX-A nrPDB 670 0.0 5DJW-A nrPDB 633 0.0 6JR6-A nrPDB 613 e-175 2G3M-A nrPDB 595 e-170 3POC-A nrPDB 588 e-168 5I24-A nrPDB 560 e-159 5F7C-A nrPDB 537 e-153 1XSK-A nrPDB 505 e-143 5JOV-A nrPDB 493 e-139 5I0E-B nrPDB 441 e-124 5X3I-A nrPDB 414 e-115 5AEG-A nrPDB 398 e-111 6DRU-A nrPDB 362 e-100 4XPS-A nrPDB 305 6e-83 5OHS-A nrPDB 304 9e-83 Sequences not found previously or not previously below threshold: 3MI6-A nrPDB 60 5e-09 5M0X-A nrPDB 58 2e-08 2YFN-A nrPDB 47 3e-05 2XN1-A nrPDB 45 2e-04 1HI7-A nrPDB 43 7e-04 2AAA-A nrPDB 41 0.004 4GKL-A nrPDB 40 0.004 1PSP-A nrPDB 40 0.005 5OT1-A nrPDB 39 0.007 5MX0-A nrPDB 39 0.015 5A2B-A nrPDB 38 0.016 3WY1-A nrPDB 38 0.017 6JEQ-A nrPDB 37 0.026 2E8Y-A nrPDB 37 0.046 4CGT-A nrPDB 37 0.054 5BRQ-A nrPDB 36 0.097 1LWJ-A nrPDB 36 0.12 2VNC-A nrPDB 35 0.16 5GSL-A nrPDB 35 0.19 3EYP-A nrPDB 35 0.21 4NZJ-A nrPDB 34 0.27 1Z9L-A nrPDB 34 0.32 5WCZ-A nrPDB 34 0.37 5BXR-A nrPDB 34 0.37 2CRI-A nrPDB 34 0.39 1EHA-A nrPDB 34 0.39 5MDX-4 nrPDB 34 0.44 5XNL-4 nrPDB 33 0.52 4OGZ-A nrPDB 33 0.53 5M99-B nrPDB 33 0.74 3K1D-A nrPDB 33 0.80 3AWQ-A nrPDB 32 1.1 1AKN-A nrPDB 32 1.2 2WSK-A nrPDB 32 1.6 5X7U-A nrPDB 31 3.3 5FA5-B nrPDB 31 3.6 3ATQ-A nrPDB 30 4.1 4PNG-A nrPDB 30 4.3 5GSM-A nrPDB 30 4.3 >5KZW-A nrPDB Length = 874 Score = 1290 bits (3337), Expect = 0.0, Method: Composition-based stats. Identities = 872/874 (99%), Positives = 873/874 (99%) Query: 79 PTQCDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFPPSYPSYKL 138 PTQCDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFPPSYPSYKL Sbjct: 1 PTQCDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFPPSYPSYKL 60 Query: 139 ENLSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETP 198 ENLSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETP Sbjct: 61 ENLSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETP 120 Query: 199 HVHSRAPSPLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYIT 258 HVHSRAPSPLYSVEFSEEPFGVIV RQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYIT Sbjct: 121 HVHSRAPSPLYSVEFSEEPFGVIVHRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYIT 180 Query: 259 GLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAM 318 GLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAM Sbjct: 181 GLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAM 240 Query: 319 DVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGY 378 DVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGY Sbjct: 241 DVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGY 300 Query: 379 SSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRY 438 SSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRY Sbjct: 301 SSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRY 360 Query: 439 MMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAW 498 MMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAW Sbjct: 361 MMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAW 420 Query: 499 WEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATIC 558 WEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATIC Sbjct: 421 WEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATIC 480 Query: 559 ASSHQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVW 618 ASSHQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVW Sbjct: 481 ASSHQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVW 540 Query: 619 SSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLL 678 SSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLL Sbjct: 541 SSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLL 600 Query: 679 SLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTW 738 SLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTW Sbjct: 601 SLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTW 660 Query: 739 TVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAI 798 TVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVP+EALGSLPPPPAAPREPAI Sbjct: 661 TVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPIEALGSLPPPPAAPREPAI 720 Query: 799 HSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELF 858 HSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELF Sbjct: 721 HSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELF 780 Query: 859 WDDGESLEVLERGAYTQVIFLARNNTIVNELVRVTSEGAGLQLQKVTVLGVATAPQQVLS 918 WDDGESLEVLERGAYTQVIFLARNNTIVNELVRVTSEGAGLQLQKVTVLGVATAPQQVLS Sbjct: 781 WDDGESLEVLERGAYTQVIFLARNNTIVNELVRVTSEGAGLQLQKVTVLGVATAPQQVLS 840 Query: 919 NGVPVSNFTYSPDTKVLDICVSLLMGEQFLVSWC 952 NGVPVSNFTYSPDTKVLDICVSLLMGEQFLVSWC Sbjct: 841 NGVPVSNFTYSPDTKVLDICVSLLMGEQFLVSWC 874 >3LPO-A nrPDB Length = 898 Score = 1065 bits (2754), Expect = 0.0, Method: Composition-based stats. Identities = 380/910 (41%), Positives = 536/910 (58%), Gaps = 47/910 (5%) Query: 63 PGPRDAQAHPGRPRAVPTQCDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQM 122 P + G R P + P N R +C P++ T+ C RGCC+ P L Sbjct: 15 PTTENLYFQSGIRRKCPNVLNDPVNVRINCIPEQFPTEGICAQRGCCWRPWNDSL----- 69 Query: 123 GQPWCFFPPSYPSYKLENLSSSEMGYTATLTRT-TPTFFPKDILTLRLDVMMETENRLHF 181 PWCFF ++ Y +++++++ +G A L R +PT F DI ++ +T NR F Sbjct: 70 -IPWCFFVDNH-GYNVQDMTTTSIGVEAKLNRIPSPTLFGNDINSVLFTTQNQTPNRFRF 127 Query: 182 TIKDPANRRYEVPLETPHVHS--RAPSPLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPL 239 I DP NRRYEVP + + LY V+ ++ PF + V R+ +G+ L +T++ PL Sbjct: 128 KITDPNNRRYEVPHQYVKEFTGPTVSDTLYDVKVAQNPFSIQVIRKSNGKTLFDTSIGPL 187 Query: 240 FFADQFLQLSTSLPSQYITGLAEHLSP-LMLSTSWTRITLWNRDLAP-TPGANLYGSHPF 297 ++DQ+LQ+S LPS YI G+ E + SW ++ RD P NLYG F Sbjct: 188 VYSDQYLQISARLPSDYIYGIGEQVHKRFRHDLSWKTWPIFTRDQLPGDNNNNLYGHQTF 247 Query: 298 YLALED-GGSAHGVFLLNSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLD 356 ++ +ED G + GVFL+NSNAM++ +QP+P +++R TGGILD YI LG P+ VVQQY Sbjct: 248 FMCIEDTSGKSFGVFLMNSNAMEIFIQPTPIVTYRVTGGILDFYILLGDTPEQVVQQYQQ 307 Query: 357 VVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTF 416 +VG P MP YW LGF L RW Y S + ++VV A P D Q D+DYM+ ++DFT+ Sbjct: 308 LVGLPAMPAYWNLGFQLSRWNYKSLDVVKEVVRRNREAGIPFDTQVTDIDYMEDKKDFTY 367 Query: 417 NKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGS--YRPYDEGLRRGVFITNETGQ 474 ++ F P VQ+LH G++Y++I+DPAIS A Y Y+ G + V+I G Sbjct: 368 DQVAFNGLPQFVQDLHDHGQKYVIILDPAISIGRRANGTTYATYERGNTQHVWINESDGS 427 Query: 475 -PLIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGC 533 P+IG+VWPG T +PDFTNP + WW + + FH +V +DG+WIDMNE S+FI+GS GC Sbjct: 428 TPIIGEVWPGLTVYPDFTNPNCIDWWANECSIFHQEVQYDGLWIDMNEVSSFIQGSTKGC 487 Query: 534 PNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHRALVKA-RG 592 N+L PP+ P ++ + + TIC + Q Y++H+LYG + AIA+ +A+ K Sbjct: 488 NVNKLNYPPFTPDILDKLMYSKTICMDAVQNWGKQYDVHSLYGYSMAIATEQAVQKVFPN 547 Query: 593 TRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFLGN 652 R F+++RSTFAG GR+A HW GD +SWEQ+ S+ +L+F+L G+PLVGAD+CGF+ Sbjct: 548 KRSFILTRSTFAGSGRHAAHWLGDNTASWEQMEWSITGMLEFSLFGIPLVGADICGFVAE 607 Query: 653 TSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPA--QQAMRKALTLRYALLPHLY 710 T+EELC RW QLGAFYPF RNHNS Q+P F + + ++ R+ LT+RY LLP LY Sbjct: 608 TTEELCRRWMQLGAFYPFSRNHNSDGYEHQDPAFFGQNSLLVKSSRQYLTIRYTLLPFLY 667 Query: 711 TLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLG 770 TLF++AHV GETVARP+ EF +D+++W D + LWG ALLITPVL+ G V+ Y P Sbjct: 668 TLFYKAHVFGETVARPVLHEFYEDTNSWIEDTEFLWGPALLITPVLKQGADTVSAYIPDA 727 Query: 771 TWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPG 830 WYD ++ Q V + P D I +HLR GYIIP+Q P Sbjct: 728 IWYDYESGAKRP-----------------WRKQRVDMYLPADKIGLHLRGGYIIPIQEPD 770 Query: 831 LTTTESRQQPMALAVALTKGGEARGELFWDDGESLEVLERGAYTQVIFLARNNTIVNELV 890 +TTT SR+ P+ L VAL + A+G+ FWDDGE+ + ++ G Y F NNT+ ++V Sbjct: 771 VTTTASRKNPLGLIVALGENNTAKGDFFWDDGETKDTIQNGNYILYTFSVSNNTL--DIV 828 Query: 891 RVTS---EGAGLQLQKVTVLGVATAPQQ--VLSNGVPV---SNFTYSPDTKVLDI-CVSL 941 S EG L Q V +LG+ + + V N P+ SNFTY +VL I + L Sbjct: 829 CTHSSYQEGTTLAFQTVKILGLTDSVTEVRVAENNQPMNAHSNFTYDASNQVLLIADLKL 888 Query: 942 LMGEQFLVSW 951 +G F V W Sbjct: 889 NLGRNFSVQW 898 >3L4Y-A nrPDB Length = 875 Score = 1037 bits (2681), Expect = 0.0, Method: Composition-based stats. Identities = 388/882 (43%), Positives = 519/882 (58%), Gaps = 44/882 (4%) Query: 89 RFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFPPSYPSYKLE-NLSSSEMG 147 R +C PD+ T+ C+ RGCC+ P QGA + PWC++ ++ SY +E NL ++ G Sbjct: 12 RINCIPDQPPTKATCDQRGCCWNP-----QGA-VSVPWCYYSKNH-SYHVEGNLVNTNAG 64 Query: 148 YTATLTR--TTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETPHVHS--R 203 +TA L ++P F ++ + L +T NR HF + D N R+EVP E S Sbjct: 65 FTARLKNLPSSPV-FGSNVDNVLLTAEYQTSNRFHFKLTDQTNNRFEVPHEHVQSFSGNA 123 Query: 204 APSPLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYITGLAEH 263 A S Y VE S +PF + V R+ + RVL ++++ PL FADQFLQLST LPS + GL EH Sbjct: 124 AASLTYQVEISRQPFSIKVTRRSNNRVLFDSSIGPLLFADQFLQLSTRLPSTNVYGLGEH 183 Query: 264 LSP-LMLSTSWTRITLWNRDLAPT-PGANLYGSHPFYLALED-GGSAHGVFLLNSNAMDV 320 + +W ++NRD P G NLYG+ F+L LED G + GVFL+NSNAM+V Sbjct: 184 VHQQYRHDMNWKTWPIFNRDTTPNGNGTNLYGAQTFFLCLEDASGLSFGVFLMNSNAMEV 243 Query: 321 VLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSS 380 VLQP+PA+++R+ GGILD Y+FLG P+ VVQ+YL+++G P +P YW LGFHL R+ Y + Sbjct: 244 VLQPAPAITYRTIGGILDFYVFLGNTPEQVVQEYLELIGRPALPSYWALGFHLSRYEYGT 303 Query: 381 TAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMM 440 R+VVE A P DVQ D+DYMD RRDFT++ F+ FP V ELH G++ ++ Sbjct: 304 LDNMREVVERNRAAQLPYDVQHADIDYMDERRDFTYDSVDFKGFPEFVNELHNNGQKLVI 363 Query: 441 IVDPAISSS-GPAGSYRPYDEGLRRGVFITNETG-QPLIGKVWPGSTAFPDFTNPTALAW 498 IVDPAIS++ + Y PYD G +++ + G PLIG+VWPG T FPD+TNP W Sbjct: 364 IVDPAISNNSSSSKPYGPYDRGSDMKIWVNSSDGVTPLIGEVWPGQTVFPDYTNPNCAVW 423 Query: 499 WEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATIC 558 W FH+QV FDG+WIDMNE SNF+ GS GC N L NPP+ P ++ G L T+C Sbjct: 424 WTKEFELFHNQVEFDGIWIDMNEVSNFVDGSVSGCSTNNLNNPPFTPRILDGYLFCKTLC 483 Query: 559 ASSHQFLSTHYNLHNLYGLTEAIASHRALVKA-RGTRPFVISRSTFAGHGRYAGHWTGDV 617 + Q Y++HNLYG + A+A+ A R F+++RSTFAG G++A HW GD Sbjct: 484 MDAVQHWGKQYDIHNLYGYSMAVATAEAAKTVFPNKRSFILTRSTFAGSGKFAAHWLGDN 543 Query: 618 WSSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSL 677 ++W+ L S+P +L+FNL G+P+VG D+CGF +T EELC RW QLGAFYPF RNHN Sbjct: 544 TATWDDLRWSIPGVLEFNLFGIPMVGPDICGFALDTPEELCRRWMQLGAFYPFSRNHNGQ 603 Query: 678 LSLPQEPYSFSEPA--QQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDS 735 Q+P SF + + R L +RY LLP+LYTLF +AH G+TVARPL EF +D+ Sbjct: 604 GYKDQDPASFGADSLLLNSSRHYLNIRYTLLPYLYTLFFRAHSRGDTVARPLLHEFYEDN 663 Query: 736 STWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPRE 795 STW V Q LWG LLITPVL G +V Y P WYD +T Sbjct: 664 STWDVHQQFLWGPGLLITPVLDEGAEKVMAYVPDAVWYDYETGS---------------- 707 Query: 796 PAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARG 855 + Q V + P D I +HLR GYI P Q P TT SR+ P+ L +AL + EA+G Sbjct: 708 -QVRWRKQKVEMELPGDKIGLHLRGGYIFPTQQPNTTTLASRKNPLGLIIALDENKEAKG 766 Query: 856 ELFWDDGESLEVLERGAYTQVIFLARNNTI-VNELVRVTSEGAGLQLQKVTVLGVATAPQ 914 ELFWDDGE+ + + Y F N + VN + L ++ +LG Sbjct: 767 ELFWDDGETKDTVANKVYLLCEFSVTQNRLEVNISQSTYKDPNNLAFNEIKILGTEEPSN 826 Query: 915 -QVLSNGVPVS---NFTYSPDTKVLDI-CVSLLMGEQFLVSW 951 V NGVP TY + KV I + LL+GE + V W Sbjct: 827 VTVKHNGVPSQTSPTVTYDSNLKVAIITDIDLLLGEAYTVEW 868 >3TOP-A nrPDB Length = 908 Score = 949 bits (2452), Expect = 0.0, Method: Composition-based stats. Identities = 351/904 (38%), Positives = 491/904 (54%), Gaps = 79/904 (8%) Query: 89 RFDCAPDK-AITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFPPSYPSYKLENLSSSEMG 147 + DC PD+ + E C ARGC + + G P+C+F Y + ++ + G Sbjct: 12 KIDCYPDENGASAENCTARGCIWEASNSS------GVPFCYFVNDL--YSVSDVQYNSHG 63 Query: 148 YTATLTRTTPTF---FPKD-ILTLRLDVMMETENRLHFTIKDPANRRYEVP--LETPHVH 201 TA ++ + + FP + LRLDV L F I DP RYEVP L P + Sbjct: 64 ATADISLKSSVYANAFPSTPVNPLRLDVTYHKNEMLQFKIYDPNKNRYEVPVPLNIPSMP 123 Query: 202 SRAPS-PLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYITGL 260 S P LY V + PFG+ +RR+ G ++ ++ + F+D F+++ST LPS+Y+ G Sbjct: 124 SSTPEGQLYDVLIKKNPFGIEIRRKSTGTIIWDSQLLGFTFSDMFIRISTRLPSKYLYGF 183 Query: 261 AEHLS-PLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAMD 319 E W +++RD P N YG HP+Y+ LE+ GSAHGV LLNSNAMD Sbjct: 184 GETEHRSYRRDLEWHTWGMFSRDQPPGYKKNSYGVHPYYMGLEEDGSAHGVLLLNSNAMD 243 Query: 320 VVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYS 379 V QP PAL++R+TGG+LD Y+FLGP P+ V QQY +++G P M PYW LGF LCR+GY Sbjct: 244 VTFQPLPALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQ 303 Query: 380 STAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYM 439 + + + + M A P DVQ++D+DYM+ + DFT + F FPA++ + G R + Sbjct: 304 NDSEIASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPK-FAGFPALINRMKADGMRVI 362 Query: 440 MIVDPAISSSGPAGSYRPYDEGLRRGVFITNE-TGQPLIGKVWP---------------- 482 +I+DPAIS + Y + G+ VFI G + GKVWP Sbjct: 363 LILDPAISGN-ETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQ 421 Query: 483 -----GSTAFPDFTNPTALAWWEDMVAEFHDQ-------VPFDGMWIDMNEPSNFIRGSE 530 AFPDF + WW+ + E ++ + FDGMWIDMNEPS+F+ G+ Sbjct: 422 VELYRAYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAV 481 Query: 531 D-GCPNNELENPPYVPGVVGGT--LQAATICASSHQ-----FLSTHYNLHNLYGLTEAIA 582 GC + L +PPY+P + L + T+C S Q L HYN+HNLYG ++ Sbjct: 482 SPGCRDASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRP 541 Query: 583 SHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLV 642 ++ A+ + G R VI+RSTF GR+AGHW GD ++W+QL S+ +++F+L G+ Sbjct: 542 TYEAVQEVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYT 601 Query: 643 GADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLR 702 GAD+CGF + E+CVRW QLGAFYPF RNHN++ + Q+P S+ R L R Sbjct: 602 GADICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDVAFVNISRTVLQTR 661 Query: 703 YALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAE 762 Y LLP+LYTL H+AH G TV RPL EF D TW +D Q L G A L++PVL+ Sbjct: 662 YTLLPYLYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARN 721 Query: 763 VTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGY 822 VT YFP WYD T I++ G+W TLPAPLD IN+H+R GY Sbjct: 722 VTAYFPRARWYDYYTG-----------------VDINARGEWKTLPAPLDHINLHVRGGY 764 Query: 823 IIPLQGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESLEVLERGAYTQVIFLARN 882 I+P Q P L T SRQ+ M +AL G A G LFWDDG+S++ +G Y F A Sbjct: 765 ILPWQEPALNTHLSRQKFMGFKIALDDEGTAGGWLFWDDGQSIDTYGKGLYYLASFSASQ 824 Query: 883 NTIVNELV--RVTSEGAGLQLQKVTVLGVATAPQQVLSNGVP----VSNFTYSPDTKVLD 936 NT+ + ++ + L+L + + GV + P +S V +F P T+VL Sbjct: 825 NTMQSHIIFNNYITGTNPLKLGYIEIWGVGSVPVTSVSISVSGMVITPSFNNDPTTQVLS 884 Query: 937 ICVS 940 I V+ Sbjct: 885 IDVT 888 >3WEN-A nrPDB Length = 913 Score = 876 bits (2263), Expect = 0.0, Method: Composition-based stats. Identities = 325/853 (38%), Positives = 451/853 (52%), Gaps = 84/853 (9%) Query: 137 KLENLSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLE 196 K++N + + L R +P + P DI L E ++ L I D NRR+E+P E Sbjct: 51 KVDNSTGKSLTALLQLIRNSPVYGP-DIQFLSFTASFEEDDTLRIRITDANNRRWEIPNE 109 Query: 197 -----------------------------TPHVHSRAPSPLYSVEFSEEPFGVIVRRQLD 227 T V S S L F PFG + R+ Sbjct: 110 VLPRPPPPPSPPPLSSLQHLPKPIPQNQPTTTVLSHPHSDLVFTLFHTTPFGFTIYRKST 169 Query: 228 GRVLLNTTVAP------LFFADQFLQLSTSLPSQ--YITGLAEHLSPLMLSTSWTRITLW 279 VL + T P L + DQ+LQLS+SLP+Q ++ GL EH P +TLW Sbjct: 170 HDVLFDATPIPSNPTTFLIYKDQYLQLSSSLPAQQAHLYGLGEHTKPTFQLAHNQILTLW 229 Query: 280 NRDLAP-TPGANLYGSHPFYLALEDG---GSAHGVFLLNSNAMDVVLQPSPALSWRSTGG 335 N D+A NLYGSHPFY+ + GS HGVFLLNSN MDV ++++ GG Sbjct: 230 NADIASFNRDLNLYGSHPFYMDVRSSPMVGSTHGVFLLNSNGMDVEYT-GDRITYKVIGG 288 Query: 336 ILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAH 395 I+D+YIF G P+ V+ QY ++G P PYW GFH CRWGY VV+ A Sbjct: 289 IIDLYIFAGRTPEMVLDQYTKLIGRPAPMPYWAFGFHQCRWGYRDVNEIETVVDKYAEAR 348 Query: 396 FPLDVQWNDLDYMDSRRDFTFNKDGFR--DFPAMVQELHQGGRRYMMIVDPAISSSGPAG 453 PL+V W D+DYMD+ +DFT + F V +LH+ G+RY+ I+DP I+++ Sbjct: 349 IPLEVMWTDIDYMDAFKDFTLDPVHFPLDKMQQFVTKLHRNGQRYVPILDPGINTN---K 405 Query: 454 SYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPFD 513 SY + G++ VFI G P +G VWPG +PDF +P A ++W D + F D +P D Sbjct: 406 SYGTFIRGMQSNVFIKR-DGNPYLGSVWPGPVYYPDFLDPAARSFWVDEIKRFRDILPID 464 Query: 514 GMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQ--AATICASSHQFLS-THYN 570 G+WIDMNE SNFI + P + L+NPPY GG + + TI A++ + + T YN Sbjct: 465 GIWIDMNEASNFITSAP--TPGSTLDNPPYKINNSGGRVPINSKTIPATAMHYGNVTEYN 522 Query: 571 LHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPE 630 HNLYG E+ A+ ALV+ RPF++SRSTFAG G+Y HWTGD + W+ L S+P Sbjct: 523 AHNLYGFLESQATREALVRTSNERPFLLSRSTFAGSGKYTAHWTGDNAARWDDLQYSIPT 582 Query: 631 ILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEP 690 +L F L G+P++GAD+CGF +T+EELC RW QLGAFYPF R+H++ + QE Y + E Sbjct: 583 MLNFGLFGMPMIGADICGFAESTTEELCRRWIQLGAFYPFSRDHSARDTTHQELYLW-ES 641 Query: 691 AQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEAL 750 + R L LRY LLP+ YTL + A++ G +ARPLF FP D +T+ + Q L G + Sbjct: 642 VAASARTVLGLRYQLLPYYYTLMYDANLRGIPIARPLFFTFPDDVATYGISSQFLIGRGI 701 Query: 751 LITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAP 810 +++PVLQ G V YFP G W+ L S G +V+L AP Sbjct: 702 MVSPVLQPGAVSVNAYFPRGNWFSLFNYTSSVSVSA---------------GTYVSLSAP 746 Query: 811 LDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESLEVLE- 869 D INVH+ G I+ +QG +TT +R P L V ++ + GELF D+G +++ Sbjct: 747 PDHINVHIHEGNIVAMQGEAMTTQAARSTPFHLLVVMSDHVASTGELFLDNGIEMDIGGP 806 Query: 870 RGAYTQVIFLAR----NNTIVNELV-RVTSEGAGLQLQKVTVLGVATAPQQVLSNGVPVS 924 G +T V F A N TI +E+V R + + K+T+LG L V + Sbjct: 807 GGKWTLVRFFAESGINNLTISSEVVNRGYAMSQRWVMDKITILG--------LKRRVRIK 858 Query: 925 NFTYSPDTKVLDI 937 +T D + I Sbjct: 859 EYTVQKDAGAIKI 871 >5HJR-A nrPDB Length = 857 Score = 706 bits (1821), Expect = 0.0, Method: Composition-based stats. Identities = 234/710 (32%), Positives = 344/710 (48%), Gaps = 66/710 (9%) Query: 248 LSTSLPS-QYITGLAEHLSPLMLSTS--WTRITLWNRDLAPTPGAN---LYGSHPFYLAL 301 L SLP +++ G+ EH L L + L+N D+ N LYGS P LA Sbjct: 178 LDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGSVPVLLAH 237 Query: 302 EDGGSAHGVFLLNSNAMDVVL---QPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVV 358 G+F LN+ V + P + W S GI+DV++ LGP V +QY + Sbjct: 238 -SFHRDLGIFWLNAAETWVDISSNTPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLT 296 Query: 359 GYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNK 418 G +PP + LG+H RW Y A +V + + P DV W D+++ D +R FT++ Sbjct: 297 GTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDP 356 Query: 419 DGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIG 478 F M++ L R+ + IVDP I YR ++E G+++ G G Sbjct: 357 TRFPQPLNMLEHLASKRRKLVAIVDPHIKVDS---GYRVHEELRNHGLYVKTRDGSDYEG 413 Query: 479 KVWPGSTAFPDFTNPTALAWWEDMVAE--FHDQVPFDGMWIDMNEPSNFIRGSEDGCPNN 536 WPGS ++PDFTNP AWW +M + + P +W DMNEPS F Sbjct: 414 WCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVF----------- 462 Query: 537 ELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHRALVKARG--TR 594 N P + + + H H ++HN+YGL +A+ L++ G R Sbjct: 463 ---NGP----------EVTMLKDAVHYGGWEHRDIHNIYGLYVHMATADGLIQRSGGIER 509 Query: 595 PFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTS 654 PFV+SR+ F+G R+ WTGD + W+ L S+P L L+G+ GADV GF N Sbjct: 510 PFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLSFCGADVGGFFKNPE 569 Query: 655 EELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFH 714 EL VRW Q+GA+ PF R H L + +EP+ + Q A+R AL RY+LLP YTLF+ Sbjct: 570 PELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIRDALFQRYSLLPFWYTLFY 629 Query: 715 QAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFP--LGTW 772 QAH G V RPL++++P+D ST++++ Q + G+ALLI PV AG V Y P W Sbjct: 630 QAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALLIHPVSDAGAHGVQVYLPGQEEVW 689 Query: 773 YDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLT 832 YD+Q+ H Q + LP L +I V R G I+P Sbjct: 690 YDIQSY------------------QKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRR 731 Query: 833 TTES-RQQPMALAVALTKGGEARGELFWDDGESLEVLERGAYTQVIFLARNNTIVNELVR 891 +++ + P+ L VAL+ G A+GELF DDG + R + F +T+V+ Sbjct: 732 SSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTLVSSSAD 791 Query: 892 -VTSEGAGLQLQKVTVLGVATAPQQVL-SNGVPVS--NFTYSPDTKVLDI 937 + +++V ++G VL + G P S +F + P+T VL + Sbjct: 792 PKGHLETPIWIERVVIMGAGKPAAVVLQTKGSPESRLSFQHDPETSVLIL 841 >5IEF-A nrPDB Length = 913 Score = 700 bits (1806), Expect = 0.0, Method: Composition-based stats. Identities = 234/729 (32%), Positives = 343/729 (47%), Gaps = 85/729 (11%) Query: 248 LSTSLPS-QYITGLAEHLSPLMLSTS--WTRITLWNRDLAPTPGAN---LYGSHPFYLAL 301 L SLP +++ G+ EH L L + L+N D+ N LYGS P LA Sbjct: 214 LDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGSVPVLLAH 273 Query: 302 EDGGSAHGVFLLNSNAMDV----------------------VLQPSPALSWRSTGGILDV 339 G+F LN+ V P + W S GI+DV Sbjct: 274 -SFHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMSESGIIDV 332 Query: 340 YIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLD 399 ++ LGP V +QY + G +PP + LG+H RW Y A +V + + P D Sbjct: 333 FLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNMPCD 392 Query: 400 VQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYD 459 V W D+++ D +R FT++ F M++ L R+ + IVDP I YR ++ Sbjct: 393 VIWLDIEHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDS---GYRVHE 449 Query: 460 EGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVAE--FHDQVPFDGMWI 517 E G+++ G G WPGS ++PDFTNP AWW +M + + P +W Sbjct: 450 ELRNHGLYVKTRDGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYVWN 509 Query: 518 DMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGL 577 DMNEPS F N P + + + H H ++HN+YGL Sbjct: 510 DMNEPSVF--------------NGP----------EVTMLKDAVHYGGWEHRDIHNIYGL 545 Query: 578 TEAIASHRALVKARG--TRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFN 635 +A+ L++ G RPFV+SR+ F+G R+ WTGD + W+ L S+P L Sbjct: 546 YVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLA 605 Query: 636 LLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAM 695 L+G+ GADV GF N EL VRW Q+GA+ PF R H L + +EP+ + Q A+ Sbjct: 606 LVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAI 665 Query: 696 RKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPV 755 R AL RY+LLP YTLF+QAH G V RPL++++P+D ST++++ Q + G+ALLI PV Sbjct: 666 RDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALLIHPV 725 Query: 756 LQAGKAEVTGYFP--LGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDT 813 AG V Y P WYD+Q+ H Q + LP L + Sbjct: 726 SDAGAHGVQVYLPGQEEVWYDIQSY------------------QKHHGPQTLYLPVTLSS 767 Query: 814 INVHLRAGYIIPLQGPGLTTTES-RQQPMALAVALTKGGEARGELFWDDGESLEVLERGA 872 I V R G I+P +++ + P+ L VAL+ G A+GELF DDG + R Sbjct: 768 IPVFQRGGTIVPRWMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHE 827 Query: 873 YTQVIFLARNNTIVNELVR-VTSEGAGLQLQKVTVLGVATAPQQVL-SNGVPVS--NFTY 928 + F +T+V+ + +++V ++G VL + G P S +F + Sbjct: 828 FLLRRFSFSGSTLVSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSPESRLSFQH 887 Query: 929 SPDTKVLDI 937 P+T VL + Sbjct: 888 DPETSVLIL 896 >5DKX-A nrPDB Length = 951 Score = 670 bits (1728), Expect = 0.0, Method: Composition-based stats. Identities = 226/834 (27%), Positives = 354/834 (42%), Gaps = 100/834 (11%) Query: 160 FPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETPHVHSRAPSPLYSVEFSEEPFG 219 F I + + + H D + P + P E ++P Sbjct: 147 FEATIKFAPFSIDFKRDGASHIKFNDQG--LLNIEHWRPKI--DPPPEPEKKEGEQQPDK 202 Query: 220 VIVRRQLDGRVLLNTTVAPLFFAD----QFLQLSTSLPS-QYITGLAEHLSPLMLSTSW- 273 + D + + + + L S +++ G+ H SPL L + Sbjct: 203 KEEAPREDDSTWWEESFGGNTDSKPRGPESVGLDISFVGYEHVFGIPSHASPLSLKQTRG 262 Query: 274 ------TRITLWNRDLAPT---PGANLYGSHPFYLALEDGGSAHGVFLLNSNAMDVVLQP 324 ++N D+ LYGS PF A S G+F LN+ V + Sbjct: 263 GEGNYNEPYRMYNADVFEYILDSPMTLYGSIPFMQAHRKDSSV-GIFWLNAAETWVDITK 321 Query: 325 ----------------SPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWG 368 + W S G+LDV++FLGP PK ++ +Y ++ G MP + Sbjct: 322 GKDSKNPLALGVKSKITTRTHWFSESGLLDVFVFLGPTPKDIISKYAELTGTTAMPQEFS 381 Query: 369 LGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMV 428 LG+H CRW Y S + V M + + P DV W D++Y D ++ FT++K F+D M Sbjct: 382 LGYHQCRWNYVSDEDVKDVDRKMDKFNMPYDVIWLDIEYTDEKKYFTWDKHSFKDPIGMG 441 Query: 429 QELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFP 488 ++L GR+ + I+DP I + +Y DE + + + + G G WPGS+ + Sbjct: 442 KQLEAHGRKLVTIIDPHIKN---TNNYPVVDELKSKDLAVKTKDGSIFEGWCWPGSSHWI 498 Query: 489 DFTNPTALAWWEDMVAE--FHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPG 546 D NP A WW+ + F + +W DMNEPS F G E P + L Sbjct: 499 DAFNPAAREWWKGLFKYDKFKGTMENTFIWNDMNEPSVF-NGPEVTMPKDNL-------- 549 Query: 547 VVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHRALVKAR---GTRPFVISRSTF 603 H H ++HNL G+T A++ AL+ + RPFV++R+ F Sbjct: 550 ---------------HHGNWEHRDVHNLNGMTFQNATYHALLSRKPGEHRRPFVLTRAFF 594 Query: 604 AGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQ 663 AG R WTGD + W L +S+P +L + G P GADV GF GN ++L RW Q Sbjct: 595 AGSQRLGAMWTGDNTADWGYLKASIPMVLSQGIAGFPFAGADVGGFFGNPDKDLLTRWYQ 654 Query: 664 LGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETV 723 G FYPF R H + + +EPY EP + AL LRY+LLP YT F AH+ G + Sbjct: 655 TGIFYPFFRAHAHIDARRREPYLTGEPYNTIIAAALRLRYSLLPSWYTAFRHAHLDGTPI 714 Query: 724 ARPLFLEFPKDSSTWTVDHQLLWGE-ALLITPVLQAGKAEVTGYFPLGT-WYDLQTVPVE 781 +P+F P + + +D Q G LL PV + V + P +YD T + Sbjct: 715 IKPMFYTHPSEEAGLPIDDQFFIGNTGLLAKPVTDKDRTSVDIWIPDSEVYYDYFTYDII 774 Query: 782 ALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQG-PGLTTTESRQQP 840 + ++ + TL APL+ I + +R G++ + P ++ + P Sbjct: 775 S----------------AAKSKTATLDAPLEKIPLLMRGGHVFARRDIPRRSSALMKWDP 818 Query: 841 MALAVALTKGGEARGELFWDDGESLEVLERGAYTQVIFLARNNTIVN---ELVRVTSEGA 897 L V L +A G+L+ DDG+S + E+G Y F+ NT+ + E S Sbjct: 819 YTLVVVLGNDRKAEGDLYVDDGDSFD-YEKGQYIHRRFIFDANTLTSADYEGRDDASIKE 877 Query: 898 GLQLQKVTVLGVATAPQQVLSNGVPVS-----NFTYSPDTKVLDICVSLLMGEQ 946 G L+K+ + V ++++ G P + T + K + E+ Sbjct: 878 GEWLKKMRTVNV----EKIIVVGAPAAWKGKKTVTVESEGKTWAAAIEYNPAEK 927 >5DJW-A nrPDB Length = 697 Score = 633 bits (1632), Expect = 0.0, Method: Composition-based stats. Identities = 207/672 (30%), Positives = 295/672 (43%), Gaps = 64/672 (9%) Query: 218 FGVIVRRQLDGRVLLNTTVAP-LFFADQFLQLSTSLP-SQYITGLAEHLSPLMLSTSWTR 275 F + + G + + + P D S ++P I G E L+ + Sbjct: 23 FAIEKEPREQGALPADWVLVPEFSLTDGKANASLTVPEGTSIYGGGEVTGSLLRNG--KT 80 Query: 276 ITLWNRDLAPT---PGANLYGSHPFYLALEDGGSAHGVFLLNSNAMDVVLQPSPALSWRS 332 I LWN D G LY SHP+ + + G+A G+ + + + +S Sbjct: 81 IKLWNTDSGAYGVDKGTRLYQSHPWMMGVRKDGTAFGILFD-TTWKAELSSTDEKIELKS 139 Query: 333 TGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMT 392 G V+I P++V++ ++ G M P W LG+ CR+ YS + ++ + Sbjct: 140 EGIPFRVFIIDRESPQAVIRGLSELTGTMPMIPRWALGYQQCRFSYSPDSRVIEIADTFR 199 Query: 393 RAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPA 452 P DV W D+DYMD R FTFN F + A+ ++LH G ++DP Sbjct: 200 LKRIPCDVIWMDIDYMDGYRIFTFNPKSFPNPKAVNRDLHIRGFHSAWMIDPGAKVDP-- 257 Query: 453 GSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPF 512 +Y Y G V++ G+ G WPG+ AFPDFT+P WW ++ +F Q Sbjct: 258 -NYFVYKSGTENDVWVKTADGKNFHGDAWPGAAAFPDFTSPKVNKWWRNLYKDFLAQ-GV 315 Query: 513 DGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLH 572 DG+W D+NEP + PN + G GG L A T H H Sbjct: 316 DGVWNDVNEPQI------NDTPNKTMPEDNLHRG--GGKLPAGT-----------HLQYH 356 Query: 573 NLYGLTEAIASHRALVKA-RGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEI 631 N+YG AS ++ A RPF+++RS F G RYA WTGD S W+ L SVP Sbjct: 357 NVYGFLMVKASREGILDARPEKRPFILTRSNFLGGQRYAATWTGDNGSCWDHLKMSVPMS 416 Query: 632 LQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPA 691 L L G P GAD+ GFL N +L W GAFYPF R H + +EP+ F + Sbjct: 417 LTLGLSGQPFSGADIGGFLFNADADLFGNWIGFGAFYPFARGHACAGTNNKEPWVFGQKV 476 Query: 692 QQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALL 751 + A R AL RY LLP+ YTL H+A G + RP+F PKD S + L G+ LL Sbjct: 477 EDASRIALERRYILLPYFYTLLHEASTNGMPIMRPVFFSDPKDLSLRAEEEAFLVGDNLL 536 Query: 752 ITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPL 811 I P A P G W +L V E + + Q Sbjct: 537 IIPAFANQPA-----LPKGIWKELSLV----------------EGDQNDKYQ-------- 567 Query: 812 DTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESLEVLERG 871 + +R G IIP TTE+ P+ L V L + G+A G ++WD G+ ++G Sbjct: 568 --AKMKIRGGAIIPTGKIIQNTTENSLDPLTLLVCLDEQGKASGNMYWDAGDGW-SYKKG 624 Query: 872 AYTQVIFLARNN 883 Y+ + F+A N Sbjct: 625 DYSLLQFVAERN 636 >6JR6-A nrPDB Length = 838 Score = 613 bits (1580), Expect = e-175, Method: Composition-based stats. Identities = 181/756 (23%), Positives = 308/756 (40%), Gaps = 83/756 (10%) Query: 196 ETPHVHSRAPSPLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPLFFADQFLQLSTSL-PS 254 E P + L + ++ PF + + + + + + ++ + L Sbjct: 97 EEPSTYEIFTEQL-RIRVNKAPFQLQIFDKYQKLLFSDYAEKGFVNDNGKIRTNKVLRND 155 Query: 255 QYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGAN---LYGSHPFYLALEDGGSAHGVF 311 + GL E L+ + +WN D P G N LY S PF+++ +G+F Sbjct: 156 EQFFGLGE--KSGNLNRRGSAYKMWNSD-QPCYGVNEDPLYKSIPFFMS----SYRYGIF 208 Query: 312 LLNSNAMDV--VLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGL 369 N+ + + + S+ + G + Y G + K ++Q Y+ + G P MPP W L Sbjct: 209 FDNTYKTEFKFGSESNDYYSFEAPAGQMVYYFMFGNDYKEIIQNYIALTGKPIMPPKWAL 268 Query: 370 GFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQ 429 GF CR Y+ R++ + P D+ + D+ + + +DF + K+ + + MV+ Sbjct: 269 GFSQCRGDYTREDQAREIAAEFRKRKIPCDIIYQDIGWTEGLQDFDWRKNNYNNPKGMVK 328 Query: 430 ELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWP--GSTAF 487 +L G + ++ DP IS + + + + E G + + WP G+ Sbjct: 329 DLSDMGFKMIVSQDPVISQA----NQQQWKEADALGHLVKDVRTGKSYDMPWPWGGNCGV 384 Query: 488 PDFTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGV 547 DFT P WW + + G W DM EP+ +ED Sbjct: 385 VDFTKPEVADWWGSYQQKPLND-GVRGFWTDMGEPA---WSNED---------------- 424 Query: 548 VGGTLQAATICASSHQFLSTHYNLHNLYGLTE-AIASHRALVKARGTRPFVISRSTFAGH 606 A + L H +HN+YG T + + + R F ++R+ +AG Sbjct: 425 -------AVDRLNMKHHLGMHNEIHNVYGFTWDKVVTEQFYKHNPNKRIFQMTRAAYAGL 477 Query: 607 GRYAGHWTGDVW------SSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTSE----- 655 RY W+GD W+Q+A+ +P L + +P D+ G+ G+ + Sbjct: 478 QRYTFGWSGDSGNGSNVLDGWKQMANQIPVGLSAGMGLIPFWTCDISGYCGDIKDYDAMA 537 Query: 656 ELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQ 715 EL VRW Q G F P R H+ + EP+ F A+ RK++ L+Y L P+LYT + Sbjct: 538 ELYVRWLQFGVFTPLSRAHHEGGNAV-EPWKFGTEAENISRKSIELKYKLFPYLYTYARE 596 Query: 716 AHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDL 775 AH G + R L LE+P D T+ ++ Q L G+ LL+ PV++ G Y P G W D Sbjct: 597 AHDTGLPIMRALLLEYPNDKETFKLNGQFLVGKELLVAPVVEQGAVTKDVYLPEGEWIDF 656 Query: 776 QTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTE 835 + G QW+T+ APL+TI V ++ G IIP E Sbjct: 657 NNCKTKYKGE-----------------QWITVDAPLNTIPVFVKKGSIIPQMPVMQYIDE 699 Query: 836 SRQQPMALAVALTK-GGEARGELFWDDGESLEVLERGAYTQVIFLARNNTIVNELVRVTS 894 + P+ + E + DDGES + ER + + ++ + ++ Sbjct: 700 KKVYPVTFDIFPGNLNKETSFTFYEDDGESRD-YERDVFCKTKITSKASNEEIKITVGER 758 Query: 895 EGAGL----QLQKVTVLGVATAPQQVLSNGVPVSNF 926 E G + + + P+ V + G + N Sbjct: 759 EYKGYSPAGPRNFILKIHASNKPKDVFAGGEKLKNV 794 >2G3M-A nrPDB Length = 693 Score = 595 bits (1534), Expect = e-170, Method: Composition-based stats. Identities = 165/594 (27%), Positives = 280/594 (47%), Gaps = 51/594 (8%) Query: 254 SQYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGAN--LYGSHPFYLALEDGGSAHGVF 311 ++I GL E L R ++N D LY S P +++++D G A G F Sbjct: 61 KEHIIGLGE--KAFELDRKRKRYVMYNVDAGAYKKYQDPLYVSIPLFISVKD-GVATGYF 117 Query: 312 LLNSNA--MDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGL 369 +++ DV L+ + ++ Y+ GP + V+++Y ++ G PF+PP W Sbjct: 118 FNSASKVIFDVGLEEYDKVIVTIPEDSVEFYVIEGPRIEDVLEKYTELTGKPFLPPMWAF 177 Query: 370 GFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQ 429 G+ + R+ Y ++V+ M + F + + D+ YMDS + FT++ F + ++ Sbjct: 178 GYMISRYSYYPQDKVVELVDIMQKEGFRVAGVFLDIHYMDSYKLFTWHPYRFPEPKKLID 237 Query: 430 ELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPD 489 ELH+ + + IVD I +Y P+ G+ G F E+G+ +GK+WPG+T +PD Sbjct: 238 ELHKRNVKLITIVDHGIRVD---QNYSPFLSGM--GKFCEIESGELFVGKMWPGTTVYPD 292 Query: 490 FTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVG 549 F WW +++E+ Q DG+W+DMNEP++F R E + L P Sbjct: 293 FFREDTREWWAGLISEWLSQ-GVDGIWLDMNEPTDFSRAIEIRDVLSSL------PVQFR 345 Query: 550 GTLQAATICASSHQFLS----THYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAG 605 T + +L H + N Y L EA+A+ + + F++SR+ +AG Sbjct: 346 DDRLVTTFPDNVVHYLRGKRVKHEKVRNAYPLYEAMATFKGFRTSHRNEIFILSRAGYAG 405 Query: 606 HGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFLG------NTSEELCV 659 RYA WTGD SW+ L + +L ++ GVP VG D+ GF G + S +L V Sbjct: 406 IQRYAFIWTGDNTPSWDDLKLQLQLVLGLSISGVPFVGCDIGGFQGRNFAEIDNSMDLLV 465 Query: 660 RWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVA 719 ++ L F+PF R+H + + EP + ++ +++ + LRY LP++Y+L +A Sbjct: 466 KYYALALFFPFYRSHKATDGIDTEPVFLPDYYKEKVKEIVELRYKFLPYIYSLALEASEK 525 Query: 720 GETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVP 779 G V RPLF EF D + ++ + + G+ LL P++ ++ + P G WY+ Sbjct: 526 GHPVIRPLFYEFQDDDDMYRIEDEYMVGKYLLYAPIVSKEESRLVT-LPRGKWYNYWNGE 584 Query: 780 VEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTT 833 + S+ + ++LR G IIPL+G L Sbjct: 585 IINGKSVVKST---------------------HELPIYLREGSIIPLEGDELIV 617 >3POC-A nrPDB Length = 666 Score = 588 bits (1515), Expect = e-168, Method: Composition-based stats. Identities = 163/643 (25%), Positives = 271/643 (42%), Gaps = 46/643 (7%) Query: 254 SQYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLL 313 + GL E + + + +LYG+H F + G + G+F Sbjct: 50 DDIVYGLGESNRGINKRGYCYISNCTDDPIHTEDKRSLYGAHNFIIV--SGKTTFGLFFD 107 Query: 314 NSNAM--DVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGF 371 + + D+ L LD+Y+ G +V+Q+ V+G ++PP + GF Sbjct: 108 YPSKLTFDIGYTRMDTLKVSCENADLDIYVIEGENAYDIVKQFRRVIGRSYIPPKFAFGF 167 Query: 372 HLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQEL 431 RWGY++ R V + H P+D+ + D+DYM +DFT N+ F DFP V+E+ Sbjct: 168 GQSRWGYTTKEDFRAVAKGYRENHIPIDMIYMDIDYMQDFKDFTVNEKNFPDFPEFVKEM 227 Query: 432 HQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFT 491 R + I+D + Y Y+EG++ F E G + VWPG T FPD Sbjct: 228 KDQELRLIPIIDAGVKVE---KGYEVYEEGVKNNYFCKREDGSDFVAAVWPGDTHFPDML 284 Query: 492 NPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGT 551 NP A W+ D DQ +G W MNEP+ F S +G + + G Sbjct: 285 NPEARKWFGDKYRFLIDQ-GIEGFWNAMNEPAIFY--SSEGLAEAKEFAGEFAKDTEGKI 341 Query: 552 LQ------AATICASSHQFLSTHYN----------LHNLYGLTEAIASHRALVKARGTRP 595 I S + ++N +HNL+G A+ A + + Sbjct: 342 HPWAMQAKMKDIVNSPEDYKRFYHNVNGKKIRHDKVHNLFGYNMTRAAGEAFERIDPEKR 401 Query: 596 FVI-SRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTS 654 F++ SRS++ G RY G W GD S W + ++ + N+ G GAD+ GF +T+ Sbjct: 402 FLMFSRSSYIGMHRYGGIWMGDNKSWWSHILLNLKMLPSLNMCGFMYTGADLGGFGDDTT 461 Query: 655 EELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFH 714 +L +R+ LG F P MR+H + + QE Y F + R + RY L+P+LY+ + Sbjct: 462 RDLLLRFLALGVFTPLMRDHAAEGTREQECYQFENI--EDFRSVINARYRLVPYLYSEYM 519 Query: 715 QAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYD 774 +A + + +PL +P D V+ QL+ G ++I PV + Y P + Sbjct: 520 KAALNDDMYFKPLGFVYPDDKMAIRVEDQLMLGNEIMIAPVYEQNARGRYVYLPE----E 575 Query: 775 LQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTT 834 ++ + GS+ E +H + L+ + + +R+G IP+ Sbjct: 576 MKFIKFMPDGSISEEVL---EKGVH------YVDVALNEVPLFIRSGKCIPVAEAAECVK 626 Query: 835 ESRQQPMALAVALTKGGEARGELFWDDGESLEVLERGAYTQVI 877 + + M L + L+ DDG + ++ Y + Sbjct: 627 DIDTENMQLI----GYEGSSYTLYEDDGIHKDYDKKENYRVLT 665 >5I24-A nrPDB Length = 836 Score = 560 bits (1442), Expect = e-159, Method: Composition-based stats. Identities = 177/722 (24%), Positives = 291/722 (40%), Gaps = 86/722 (11%) Query: 213 FSEEPFGVIVRRQLDGRVLLNTTVAPLFFADQFLQLSTSL-PSQYITGLAEHLSPLMLST 271 + PF + R + LL + + L P + I G + + L + Sbjct: 89 IQKRPFAISYYRDSE---LLLAEESGFQVNTDKINFRFYLSPGEKILGGGQRI--LGMDR 143 Query: 272 SWTRITLWNRDLAPTPGA--NLYGSHPFYLALEDGGSAHGVFLLNSN--AMDVVLQPSPA 327 R L+NR +Y P ++ + + NS AMD+ S Sbjct: 144 RGQRFPLYNRAHYGYSDHSGQMYFGLPAIMS----SKQYILVFDNSASGAMDIGKTESDI 199 Query: 328 LSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQV 387 L + G + G S+++ + V G +PP W LG R+GY S A TR Sbjct: 200 LQLEAKSGRSAYILVAGNSYPSLIENFTQVTGRQPLPPRWALGSFASRFGYRSEAETRAT 259 Query: 388 VENMTRAHFPLDVQ-----WNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIV 442 V+ FPLD W D + ++K+ F M+ + Q G + ++I Sbjct: 260 VQKYKTEDFPLDTIVLDLYWFGKDIKGHMGNLDWDKENFPTPLDMMADFKQQGVKTVLIT 319 Query: 443 DPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDM 502 +P + +S + +D+ ++ + GQP +++ G+ D + W+ + Sbjct: 320 EPFVLTSS-----KRWDDAVKAKALAKDPQGQPKAFELYFGNGGIIDVFSKEGSRWFSSI 374 Query: 503 VAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSH 562 + Q G W D+ EP +P +G Sbjct: 375 YKDLSKQ-GVAGWWGDLGEPEM---------------HPEDTQHAIGDADT--------- 409 Query: 563 QFLSTHYNLHNLYGLTEA-IASHRALVKARGTRPFVISRSTFAGHGRYAGH-WTGDVWSS 620 +HN YG A + + L + RPF++ R+ F G RY WTGDV + Sbjct: 410 --------VHNAYGHRWAEMLYQQQLDQFPELRPFIMMRAGFVGSQRYGMIPWTGDVSRT 461 Query: 621 WEQLASSVPEILQFNLLGVPLVGADVCGFLG--NTSEELCVRWTQLGAFYPFMRNHNSLL 678 W LAS V LQ +LLG + +D+ GF +E+ +RW Q G F P R H Sbjct: 462 WGGLASQVELALQMSLLGFGYIHSDLGGFADGETLDKEMYIRWLQYGVFQPVYRPHGQ-D 520 Query: 679 SLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTW 738 +P EP E + +R + LRY +LP++YT +Q + G + RPLF K+ + Sbjct: 521 HIPSEPVFQDEETKAILRPLVKLRYRMLPYIYTAAYQNTLTGMPLMRPLFFSDEKNPALI 580 Query: 739 TVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAI 798 WG++LL+TP+ QAG V+ P G W+D ++ Sbjct: 581 DNKTSYFWGDSLLVTPITQAGVESVSIPAPKGVWFDFW-----------------KDTRY 623 Query: 799 HSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGE---ARG 855 ++G +TLP L TI V ++AG +P P ++TTE + +L + A+G Sbjct: 624 QTDGAPLTLPTDLHTIPVLVKAGAFMPYV-PAVSTTEDYRSD-SLEIHYYADASVPLAQG 681 Query: 856 ELFWDDGESLEVLERGAYTQVIFLA--RNNTIVNELVRVTSEGAGLQLQKVTVLGVATAP 913 E+F DDG+ ++R + + A +N + +L R G+ ++ T L + A Sbjct: 682 EIFEDDGKDPNSIKRNQFDLLTLQATHTDNQLHFQLARTGKGYRGMPERRATTLVIHNAS 741 Query: 914 QQ 915 Q Sbjct: 742 DQ 743 >5F7C-A nrPDB Length = 761 Score = 537 bits (1384), Expect = e-153, Method: Composition-based stats. Identities = 137/620 (22%), Positives = 237/620 (38%), Gaps = 82/620 (13%) Query: 251 SLPSQYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGV 310 S P + G E + LS + L N+D Y + PFYL+ +G Sbjct: 198 SRPDECFAGTGERFFKMDLSGQ--TLFLKNQDGQGVNNRRTYKNIPFYLS----SRMYGT 251 Query: 311 FL--LNSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWG 368 F + + + + ++ + S +LD ++ G + +++ Y D+ GYP MPP W Sbjct: 252 FYHTCAHSKLSLAGHSTRSVQFLSDQAMLDAFVIAGDTMEEILRGYRDLTGYPSMPPLWS 311 Query: 369 LGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDY--MDSRRDFTFNKDGFRDFPA 426 G + R Y S ++ + M H+P DV D + D ++ FN++ F D Sbjct: 312 FGVWMSRMTYFSADEVNEICDRMRAEHYPCDVIHLDTGWFRTDWLCEWKFNEERFPDPKG 371 Query: 427 MVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTA 486 +Q L + G R + P ++ +E + + G + G+ Sbjct: 372 FIQRLKKNGYRVSLWQLPYVAEDAEQIEEAKANEYIAPLTKQQDTDGSNFSALDYAGT-- 429 Query: 487 FPDFTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPG 546 DFT P A W++ ++ + +DM C + ++ Sbjct: 430 -IDFTYPKATEWYKGLLKQL----------LDMG----------VTCIKTDFGENIHMDA 468 Query: 547 VVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGH 606 V G + + Y + K V +R+ +AG Sbjct: 469 VYKGMKPELLNNLYALLYQKAAYEI----------------TKEVTGDGIVWARAAWAGC 512 Query: 607 GRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGF-----LGN--TSEELCV 659 RY HW GD SSW+ +A S+ L F L G DV GF N +E++ + Sbjct: 513 QRYPLHWGGDSCSSWDGMAGSLKGGLHFGLSGFAFWSHDVPGFHTLPNFMNSIVAEDVYM 572 Query: 660 RWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVA 719 RWTQ G F +R H + +EP+ + A ++K LRY+L+P++ A + Sbjct: 573 RWTQFGVFTSHIRYHG---TNKREPWHYPAIA-PLVKKWWKLRYSLIPYIIEQSKLAVES 628 Query: 720 GETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVP 779 G + + L L P+D W +D + +G L+ PV+ + Y P G W + T Sbjct: 629 GWPLLQALILHHPEDKLCWHIDDEYYFGNDFLVAPVMNSENR-RDIYLPEGQWVNFFTGE 687 Query: 780 VEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQ 839 G + PL+ + V++R +IP+ + T+ + Sbjct: 688 RLQGGRWLKE-----------------VYVPLEEMPVYVRENAVIPIYPEEVNCTD--EM 728 Query: 840 PMALAVALTKGGEARGELFW 859 + ++AL +G FW Sbjct: 729 DLGKSIALRIDHNYKG--FW 746 >1XSK-A nrPDB Length = 778 Score = 505 bits (1301), Expect = e-143, Method: Composition-based stats. Identities = 145/719 (20%), Positives = 248/719 (34%), Gaps = 119/719 (16%) Query: 244 QFLQLSTSLPSQYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALED 303 F +L + + + GL E + L+ + + WNRD T Y + PFY+ Sbjct: 150 MFERLDLGV-GETVYGLGERFTALVRNGQ--TVETWNRD-GGTSTEQAYKNIPFYMT--- 202 Query: 304 GGSAHGVFLLNSN--AMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYP 361 +GV + + + +V + + + L+ ++ GP PK+V+ +Y G P Sbjct: 203 -NRGYGVLVNHPQCVSFEVGSEKVSKVQFSVESEYLEYFVIDGPTPKAVLDRYTRFTGRP 261 Query: 362 FMPPYWGLGFHLCR--WGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDS--RRDFTFN 417 +PP W G L A ++ M + PL V D +M + DF ++ Sbjct: 262 ALPPAWSFGLWLTTSFTTNYDEATVNSFIDGMAERNLPLHVFHFDCFWMKAFQWCDFEWD 321 Query: 418 KDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLI 477 F D M++ L G + + ++P I P + E +G + G Sbjct: 322 PLTFPDPEGMIRRLKAKGLKICVWINPYIGQKSP-----VFKELQEKGYLLKRPDGSLWQ 376 Query: 478 GKVWPGSTAFPDFTNPTALAWWEDMVA------------EFHDQVPFDGMWIDMNEPSNF 525 W A DFTNP A W+ D + +F +++P D W D ++P Sbjct: 377 WDKWQPGLAIYDFTNPDACKWYADKLKGLVAMGVDCFKTDFGERIPTDVQWFDGSDPQKM 436 Query: 526 IRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHR 585 H + YN L + + Sbjct: 437 ------------------------------------HNHYAYIYNELVWNVLKDTVGEEE 460 Query: 586 ALVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGAD 645 A + +RS G ++ HW GD ++++E +A S+ L L G D Sbjct: 461 A---------VLFARSASVGAQKFPVHWGGDCYANYESMAESLRGGLSIGLSGFGFWSHD 511 Query: 646 VCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLRYAL 705 + GF + RW G R H S + P+++ + + +R L+ + Sbjct: 512 IGGFENTAPAHVYKRWCAFGLLSSHSRLHGS--KSYRVPWAYDDESCDVVRFFTQLKCRM 569 Query: 706 LPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTG 765 +P+LY +A+ G + R + +EFP D + +D Q + G+ +++ PV +V Sbjct: 570 MPYLYREAARANARGTPMMRAMMMEFPDDPACDYLDRQYMLGDNVMVAPVFTE-AGDVQF 628 Query: 766 YFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIP 825 Y P G W L +W ++ V++R ++ Sbjct: 629 YLPEGRWTHLW------------------HNDELDGSRWHKQQHGFLSLPVYVRDNTLLA 670 Query: 826 LQGPGLTTTESRQQPMAL-AVALTKGGEARGELFWDDGESLEVLERGAYTQVIFLARNNT 884 L + A L G EA E+ DG VIF + Sbjct: 671 LGNNDQRPDYVWHEGTAFHLFNLQDGHEAVCEVPAADGS------------VIFTLKAAR 718 Query: 885 IVNELVRVTSEGAGLQL----QKVTVLGVATAPQQVLSNGVPVSNFTYSPDTKVLDICV 939 N + + A V V G+ Q G+ V P L I + Sbjct: 719 TGNTITVTGAGEAKNWTLCLRNVVKVNGLQDGSQAESEQGLVVK-----PQGNALTITL 772 >5JOV-A nrPDB Length = 955 Score = 493 bits (1270), Expect = e-139, Method: Composition-based stats. Identities = 150/637 (23%), Positives = 236/637 (37%), Gaps = 78/637 (12%) Query: 330 WRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVE 389 W LD Y G V+ Y + G + P W +GF R Y++ ++ Sbjct: 368 WSEMTKQLDYYFMAGENMDDVISGYRSLTGKSPVMPKWAMGFWQSREKYNTQEEMLGALK 427 Query: 390 NMTRAHFPLDVQWNDLDY--MDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAIS 447 PLD D ++ ++ F+K F D AMV +H R M+ V P Sbjct: 428 GFRDRKIPLDNIVLDWNHWPENAWGSHEFDKARFPDPKAMVDSIHAMHARMMISVWPKFY 487 Query: 448 SSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGS-TAFPDFTNPTALA-WWEDMVAE 505 + + E G L V PG F D +P A +W+ M Sbjct: 488 VTTEH-----FKEFDENGWMYQQSVKDSLKDWVGPGYHYGFYDAYDPDARKLFWKQMYEH 542 Query: 506 FHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFL 565 ++ + D W+D +EP+ C + E L T SS +F Sbjct: 543 YY-PLGIDAWWMDASEPNV------RDCTDLE----------YRKALCGPTALGSSTEFF 585 Query: 566 STHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYA-GHWTGDVWSSWEQL 624 + Y L N EAI + V R F+++RS FAG RY+ W+GD+ + WE + Sbjct: 586 NA-YALMNA----EAIYDGQRGVD-NNKRVFLLTRSGFAGLQRYSTATWSGDIGTRWEDM 639 Query: 625 ASSVPEILQFNLLGVPLVGADVCGFLGNTS---------------------EELCVRWTQ 663 + + L F + G+P D+ GF EL RW Q Sbjct: 640 KAQISAGLNFAMSGIPYWTMDIGGFCVENRYVAGQKQWNATKTENADYKEWRELNTRWYQ 699 Query: 664 LGAFYPFMRNHNSLLSLP-QEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGET 722 GAF P R H E PA Q++ LRY ++P++Y+L T Sbjct: 700 FGAFVPLYRAHGQYPFREIWEIAPEGHPAYQSVVYYTKLRYNMMPYIYSLAGMTWFDDYT 759 Query: 723 VARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGT-WYDLQTVPVE 781 + RPL ++F D+ + Q ++G + +++PV + G YFP WYD + + Sbjct: 760 IMRPLVMDFTADAEVNDIGDQFMFGPSFMVSPVYRYGDRSREIYFPQAEGWYDFYSGKFQ 819 Query: 782 ALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPM 841 A G + AP + I +++RAG IIP T E + + Sbjct: 820 AGGERKV------------------IEAPYERIPLYVRAGAIIPFGDDIQYTDEKPAEHI 861 Query: 842 ALAVALTKGGEARGELFWDDGESLEVLERGAYTQVIFLARNNTIVNEL-VRVTSEGAGLQ 900 L + +G + L+ D+G + E+G Y + T + R L+ Sbjct: 862 RLYI--YQGADGEFTLYEDEGVNYN-YEQGMYAMIPMKYDEATKTLVIGERQGEFPGMLK 918 Query: 901 LQKVTVLGVATAPQQVLSNGVPVSNFTYSPDTKVLDI 937 + TV+ V Q Y+ + L + Sbjct: 919 ERTFTVVTVNKEKAQPFDLNAKGVTVKYNGSEQTLKL 955 >5I0E-B nrPDB Length = 733 Score = 441 bits (1135), Expect = e-124, Method: Composition-based stats. Identities = 144/668 (21%), Positives = 230/668 (34%), Gaps = 103/668 (15%) Query: 202 SRAPSPLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPLFFADQFLQLSTSLP---SQYIT 258 + PL +S EP G +DG + + L + ++ +L +++ Sbjct: 120 TSESFPLTPSHWSAEPVG---HIDIDGDRFIPDSPLWLVSSAGTHRVKFALRIEGDEHVV 176 Query: 259 GLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNS--N 316 G E L ++ + A Y PF + + G A G + + Sbjct: 177 GFGERYDQLDQRGLRLDSVVFEQYKAQGKHHRTYLPMPFAQVVNEAGRAWGFHVETTRRT 236 Query: 317 AMDVVLQPSPALSWRSTGG-------ILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGL 369 DV S + G ++ V + G P V+ +LDV G P P W Sbjct: 237 WYDVAATVSDRILIEVDLGFEAEKTPVVRVNTWSG-SPTDVLNGFLDVAGRPAEMPEWIF 295 Query: 370 GFHLCRWGYSSTAITRQVVENMTRAHFPLDVQ----WNDLD----YMDSRR--------- 412 G +++ ++ + ++ P+ V W+D + + D+R Sbjct: 296 GLWASGNEWNTQSLVMEQMDRHRNEGIPVSVVVIEAWSDEEGFTIFRDARYVPNQGQPHR 355 Query: 413 --DFTFNKDG-FRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYR--PYDEGLRRGVF 467 DFT+ DG + D M++ELH+ G R ++ P + G + + G Sbjct: 356 GPDFTYPSDGAWPDPAGMIRELHERGIRVILWQIPLQKTDDDLGPEALAQGNALIASGHV 415 Query: 468 ITNETGQPLIGKVWPGSTAF-PDFTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFI 526 + G P + W A PD + WW + + + DG D E + Sbjct: 416 VKEPDGTPYKNRGWWFPNALMPDLSTEAGRQWWTEQRRYLVEDLDIDGFKTDGGEHAWGS 475 Query: 527 R-GSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHR 585 EDG + +NLY + A A + Sbjct: 476 DLRYEDGRRGD---------------------------------EGNNLYPVNYARA-YG 501 Query: 586 ALVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGAD 645 L+++ G P SRS F G + +W GD S+WE SS+ + G+ G D Sbjct: 502 DLLRSAGKYPVTFSRSGFTGSQAHGLYWAGDEDSTWEAFRSSITAGITAGACGILYWGWD 561 Query: 646 VCGFLGNTSE-ELCVRWTQLGAFYPFMR-----NHNSLLSLPQEPYSFSEPAQ-----QA 694 + GF G E EL R F P M+ +H+ L + P++ +E Sbjct: 562 LAGFSGPVPEAELYARAFAAATFMPIMQYHSEFHHHELPLRDRTPWNVAEQTGCGELIDL 621 Query: 695 MRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITP 754 R +R AL P+L Q G+ + R +F + D W Q + G+ LLI P Sbjct: 622 ARHYTRVREALRPYLVAQTRQCLQTGKPLMRAMFYDHADDPEIWAHPRQYMLGDELLINP 681 Query: 755 VLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTI 814 V G T Y P G W D + V G L D I Sbjct: 682 VTAPGATTWTTYLPEGQWEDYWSGEVSEGGHLVTRA------------------VGWDII 723 Query: 815 NVHLRAGY 822 V+ R G Sbjct: 724 PVYRRVGA 731 >5X3I-A nrPDB Length = 743 Score = 414 bits (1063), Expect = e-115, Method: Composition-based stats. Identities = 128/593 (21%), Positives = 201/593 (33%), Gaps = 72/593 (12%) Query: 254 SQYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLL 313 + G E L ++ + A Y PF + G+ G + Sbjct: 183 GDRLVGFGERYDALDQRGRELDAVVFEQYKAQGVHGRTYLPMPFAHVVGADGNGWGFHVR 242 Query: 314 NSNAMDVVLQPSPALSWRSTGG---ILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLG 370 S L+ G ++D+ I+ G +P +V+ +LD VG P W Sbjct: 243 TSRRTWY-SSAGNELTVEVALGDEPVVDLAIYEG-DPATVLTGFLDEVGRAEELPGWVFR 300 Query: 371 FHLCRWGYSSTAITRQVVENMTRAHFPLD-------------VQWNDLDYMDSR------ 411 +++ + ++ P+ W D Y + Sbjct: 301 LWASGNEWNTQQLVTARMDTHRDLAIPVGAVVIEAWSDEQGITIWRDAVYAVTEDGSAHR 360 Query: 412 -RDFTFNKDG-FRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGL-RRGVFI 468 DF++ DG + D AM+ ELH G + ++ P + G + R G + Sbjct: 361 AEDFSYRPDGAWPDPKAMIDELHARGIKVILWQIPLQKTEFSTGQVAADAAAMVRDGHAV 420 Query: 469 TNETGQPLIGKVWPGSTAF-PDFTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIR 527 G + W A PD + WW + + DG E + Sbjct: 421 LEADGTAYRNRGWWFPQALMPDLSVQRTRDWWTEKRRYLVEHFDVDGFKTAGGEHA---- 476 Query: 528 GSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHRAL 587 ++ + Y G G +NLY + A A L Sbjct: 477 -----WGHDLV----YADGRKGD-------------------EGNNLYPVHYARA-FGDL 507 Query: 588 VKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVC 647 +++ G P SR+ F G + W GD S+W+ SSV L G+ G D+ Sbjct: 508 LRSAGKAPVTFSRAGFTGSQAHGIFWAGDEDSTWQAFRSSVTAGLTAASCGIVYWGWDLA 567 Query: 648 GFLGNTSE-ELCVRWTQLGAFYPFMR-----NHNSLLSLPQEPYSFSEPAQQA-----MR 696 GF G + EL +R AF P M+ NH+ L + P+ +E R Sbjct: 568 GFSGPVPDAELYLRAAAASAFMPIMQYHSEFNHHQLPLRDRTPWHVAETTGDDRVVPLFR 627 Query: 697 KALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVL 756 + TLR +L+P+L + + RPLF + D W +Q L G+ LLI PVL Sbjct: 628 RFATLRESLVPYLTEQAARTIATDRPLMRPLFFDHENDPEIWNHPYQYLLGDELLINPVL 687 Query: 757 QAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPA 809 + G T Y P G W D+ T G + P +W L Sbjct: 688 EPGATTWTTYLPAGEWIDVWTGDRVPSGLVTRDVPLEVVPVYCRASRWSELQP 740 >5AEG-A nrPDB Length = 686 Score = 398 bits (1022), Expect = e-111, Method: Composition-based stats. Identities = 133/665 (20%), Positives = 226/665 (33%), Gaps = 111/665 (16%) Query: 208 LYSVEFSEEPFGVIVR--RQLD------------GRVLLNTTVAPLFFADQFLQLSTSLP 253 L S+ P G ++ R D GR+LL L +L+L+ P Sbjct: 67 LTDAIVSQSPDGWLIHFSRGSDISATLNISADDQGRLLLELQNDNLNHNRIWLRLAAQ-P 125 Query: 254 SQYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFL- 312 +I G E S L LW + Y + GG + F Sbjct: 126 EDHIYGCGEQFSYFDLRG--KPFPLWTSEQGVGRNKQTYVTWQADCKENAGGDYYWTFFP 183 Query: 313 --------------LNSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVV 358 NS M+ + S++++ ++ Sbjct: 184 QPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALWEDKATLRFECADTYISLLEKLTALL 243 Query: 359 GYPFMPPYWG-----LGFH------------LCRWGYSSTAITRQVVENMTRAHFPLDVQ 401 G P W LG + G I Q + F V Sbjct: 244 GRQPELPDWIYDGVTLGIQGGTEVCQKKLDTMRNAGVKVNGIWAQDWSGIRMTSFGKRVM 303 Query: 402 WNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEG 461 WN + +N + + + +++ +Q G +++ ++P ++S +E Sbjct: 304 WN----------WKWNSENYPQLDSRIKQWNQEGVQFLAYINPYVASDKDLC-----EEA 348 Query: 462 LRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPFDGMWIDMNE 521 + G + +G + + D TNP A AW+++++ + Sbjct: 349 AQHGYLAKDASGGDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKK---------------- 392 Query: 522 PSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAI 581 E GC + Y+P H +S +HN + A Sbjct: 393 -----NMIELGCGGWMADFGEYLP-----------TDTYLHNGVSAEI-MHNAWPALWAK 435 Query: 582 ASHRALVK-ARGTRPFVISRSTFAGHGRYA-GHWTGDVWSSW---EQLASSVPEILQFNL 636 ++ AL + + R+ G +Y+ W GD W + LAS VP L + Sbjct: 436 CNYEALEETGKLGEILFFMRAGSTGSQKYSTMMWAGDQNVDWSLDDGLASVVPAALSLAM 495 Query: 637 LGVPLVGADVCG----FLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQ 692 G L +D+ G F S+EL +RW AF P MR H + P + + F A+ Sbjct: 496 TGHGLHHSDIGGYTTLFEMKRSKELLLRWCDFSAFTPMMRTHE--GNRPGDNWQFDGDAE 553 Query: 693 QA--MRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEAL 750 + T+ L P+L +G V RPLFL + D+ T+T+ +Q L G + Sbjct: 554 TIAHFARMTTVFTTLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAHTYTLKYQYLLGRDI 613 Query: 751 LITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIH-SEGQWVTLPA 809 L+ PV + G+++ T Y P W T G + + P + ++ +W L A Sbjct: 614 LVAPVHEEGRSDWTLYLPEDNWVHAWTGEAFRGGEVTVNAPIGKPPVFYRADSEWAALFA 673 Query: 810 PLDTI 814 L +I Sbjct: 674 SLKSI 678 >6DRU-A nrPDB Length = 718 Score = 362 bits (928), Expect = e-100, Method: Composition-based stats. Identities = 115/601 (19%), Positives = 207/601 (34%), Gaps = 71/601 (11%) Query: 250 TSLPSQYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHG 309 ++ P + I G + ++ + I + N N Y P +++ + Sbjct: 142 SATPDEQIYGTGTQQDHM-INKKGSVIDMVN--------FNSYIPTPVFMS----NKGYA 188 Query: 310 VFLLNSNAMDVVLQPSPALSWRSTGGILDVYIFLGP--EPKSVVQQYLDVVGYPFMPPYW 367 + ++ ++D I + ++ Q+ + G PP + Sbjct: 189 FIWNMPAEGRMEFGTLRTRFTAASTTLVDYVIVAAQPGDYDTLQQRISALTGRAPAPPDF 248 Query: 368 GLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAM 427 LG+ + Y + + +N + P+ + D + D+ + + + M Sbjct: 249 SLGYIQSKLRYENQTEVELLAQNFHDRNIPVSMIVIDYQSWAHQGDWALDPRLWPNVAQM 308 Query: 428 VQELHQ-GGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTA 486 + G M + P+++ Y G+ G P W GS Sbjct: 309 SARVKNLTGAEMMASLWPSVADDSVN-----YAALQANGLLSATRDG-PGTTDSWNGSYI 362 Query: 487 F-PDFTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVP 545 D TNP+A + M+ + + WID + E+ + +E+ P+ Sbjct: 363 RNYDSTNPSARKFLWSMLKKNYYDKGIKNFWIDQADGGALGEAYENNGQSTYIESIPFT- 421 Query: 546 GVVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAG 605 L A + + Y + + E + + +SRS + G Sbjct: 422 ------LPNVNYAAGTQLSVGKLYPWAHQQAIEEGFRNATDTKEGSACDHVSLSRSGYIG 475 Query: 606 HGRYAGH-WTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTS---------- 654 R+ W+GD S W+ LA V L G D GF +++ Sbjct: 476 SQRFCSMIWSGDTTSVWDTLAVQVASGLSAAATGWGWWTVDAGGFEVDSTVWWSGNIDTP 535 Query: 655 --EELCVRWTQLGAFYPFMRNHNS-------LLSLPQEPYSFSEPAQQAMRKALTLRYAL 705 EL VRW F PFMR H S + EP+S+ + + LRY L Sbjct: 536 EYRELYVRWLAWTTFLPFMRTHGSRTCYFQDAYTCANEPWSYGASNTPIIVSYIHLRYQL 595 Query: 706 LPHLYTLFHQAHVAGETVARPLFLEFPK---------DSSTWTVDHQLLWGEALLITPVL 756 +L ++F+Q H+ G ++ RPL+++F K S++ Q ++G LL++PV Sbjct: 596 GAYLKSIFNQFHLTGRSIMRPLYMDFEKTDPKISQLVSSNSNYTTQQYMFGPRLLVSPVT 655 Query: 757 QAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINV 816 E Y P + P ++ GQ V +PAPL I V Sbjct: 656 LPNVTEWPVYLPQ------------TGQNNTKPWTYWWTNETYAGGQVVKVPAPLQHIPV 703 Query: 817 H 817 Sbjct: 704 F 704 >4XPS-A nrPDB Length = 720 Score = 305 bits (781), Expect = 6e-83, Method: Composition-based stats. Identities = 137/707 (19%), Positives = 246/707 (34%), Gaps = 146/707 (20%) Query: 255 QYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLL- 313 + + G + + + L + PFY++ + +GVF+ Sbjct: 98 EQLYGFGLNFQTVHQRG--KILELHVDHYGGKDSGRTHAPTPFYVS----SNGYGVFINS 151 Query: 314 -------------------------NSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPK 348 N++ S A+ ++VY+F GP+P Sbjct: 152 ARYIKVWAGTGVRKDSENFPTPKDRNTDKTWSSRPYSDAVEILVPAEGVEVYVFGGPKPI 211 Query: 349 SVVQQYLDVVGYPFMPPYWGLGF-HLCRWGYSSTAITRQVVENMTRAHFPLDVQ-----W 402 V++Y + G ++PP WGLGF Y+ + ++ V + +PLD W Sbjct: 212 DAVKRYNLLNGGGYLPPRWGLGFTQRVMTRYTDKDVEKE-VNDFKEKGYPLDFVGLEPGW 270 Query: 403 NDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGL 462 Y + F+++K + D + V+++ G R + ++P IS P Y E Sbjct: 271 QSKAYPGT---FSWDKSRYPDPTSFVKKMKDQGIRLNLWINPYISPDAPF-----YKE-- 320 Query: 463 RRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALA-WWEDMVAEFHDQVPFDGMWIDMNE 521 I TG VW G PDFT A ++ ++ + ++ G Sbjct: 321 -----IKPYTGSH---TVWLGL--VPDFTMAEARKPFFNQLLKDQIER-GVSG------- 362 Query: 522 PSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAI 581 Y V G A+ + + YGL Sbjct: 363 ---------------------YKIAEVDGYDYYLWPDAAKFPSGLSAEQMRQTYGLLVQR 401 Query: 582 ASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPL 641 S L K R R F + R++ G + D + + + + ++ GV L Sbjct: 402 YSAE-LYKQRNERTFGLVRASNGGGTSFPYVIYNDYY-NHQDF---ITALINSGFAGV-L 455 Query: 642 VGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTL 701 +V + S E +R Q F P + +P+S+ E + ++K L Sbjct: 456 WTPEV---RASKSGEEWLRRFQSNVFSPMAMINAWASG--TKPWSYPE-VEADVKKFALL 509 Query: 702 RYALLPHLYTLFHQAHVAGETVARPLFLE--FPKD------------------SSTWTVD 741 R ++P+ Y+ F + H G R + LE F +D +++ + Sbjct: 510 RMQMMPYWYSAFARYHFEGMPPFRGMGLEEGFRQDAKVEKLNKVNLEENPYAEAASKEIK 569 Query: 742 HQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSE 801 Q + G+ LL+ P+ AG+ P G WYD T + Sbjct: 570 DQYMAGDDLLVAPMF-AGEKSRKVVLPKGKWYDFYTGE------------------YAGD 610 Query: 802 GQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELFWDD 861 G+ + + LD I V++R G I+P+ P L + Q + L + +L+ DD Sbjct: 611 GEVLDVTPGLDKIPVYVRDGGIVPMM-PALLNSPKSNQKVDLEIRYYGNKPGEFKLYDDD 669 Query: 862 GESLEVLERGAYTQVIFLARNNTIVNELVRVTSEGAGLQLQKVTVLG 908 GE+ E+G ++ + +++ G KV +G Sbjct: 670 GETFN-YEKGDFSWRTIRVEKDKSGKVKGSISAAVKG----KVNTVG 711 >5OHS-A nrPDB Length = 672 Score = 304 bits (779), Expect = 9e-83, Method: Composition-based stats. Identities = 110/607 (18%), Positives = 185/607 (30%), Gaps = 94/607 (15%) Query: 254 SQYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGANL---------------YGSHPFY 298 +++ G E +S R LW + Y + + Sbjct: 109 DEHVWGGGEQMSYF--DMRGRRFPLWTSEPGVGRDKTTEITFKSDVSGKAGGDYYNTNYP 166 Query: 299 LALEDGGSAHGVFLLNSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVV 358 + + + S + + F G +V Sbjct: 167 QPTWLSSRKYALHVETSAYSVFDFRNGDFHEIEIWAVPEKIEFFAGDSFADIVSALSLHF 226 Query: 359 GYPFMPPYWGL-----GFHLCRWGYSSTAITR-----------QVVENMTRAHFPLDVQW 402 G P W G ++ R + + + F + W Sbjct: 227 GRQPELPDWVYNGAIIGLKDGVNSFARLEKIRAAGTKVSGLWCEDWVGLRQTSFGARLFW 286 Query: 403 NDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGL 462 D+ N + + EL G R++ V+P + GP Sbjct: 287 ----------DWQANDTRYPHLRQKIAELADQGIRFLGYVNPYLCVDGPLFPVAE----- 331 Query: 463 RRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWED-MVAEFHDQVPFDGMWIDMNE 521 G F T+ G+ + DFTNP A W+ ++ + G D E Sbjct: 332 SAGYFATDVDGKTALVDFGEFDCGVVDFTNPAAADWFAAAIIGKNMLDFGLSGWMADFGE 391 Query: 522 PSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAI 581 L + V L +HN + A Sbjct: 392 ---------------YLPIDIKLSNGVDAKL------------------MHNAWPTLWAE 418 Query: 582 ASHRALV-KARGTRPFVISRSTFAGHGRY-AGHWTGDV---WSSWEQLASSVPEILQFNL 636 + + + + + R+ F G + W G+ +S + L + + L L Sbjct: 419 VNAKGVESRGKTGEALFFMRAGFTGVQAHCPLIWGGNQSVDFSRHDGLVTVICGALSSGL 478 Query: 637 LGVPLVGADVCGF---LGNT-SEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQ 692 +G +D+ G+ GN + EL +RWT++ AF P MR H E Sbjct: 479 MGNAYHHSDIGGYTSLFGNVRTAELIMRWTEMAAFTPVMRTHEGNRPRDNLQIDQDETVL 538 Query: 693 QAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLI 752 + + AL P+L +L +A G V RPLFL + + T+ V L+G +L+ Sbjct: 539 AHFARMTAIYVALAPYLKSLSAEAAKTGLPVQRPLFLHYENEPQTYAVQDCYLYGADMLV 598 Query: 753 TPVLQAGKAEVTGYFP-LGTWYDLQTVPVEALGSLPPPPAAPREPA--IHSEGQWVTLPA 809 PV +AG+ + + Y P G W L + A G EPA ++ L Sbjct: 599 APVWKAGETQRSLYLPGHGEWVHLWSGKRHAGGRDITVETPLGEPAVFYRADSSHHRLFE 658 Query: 810 PLDTINV 816 L TI + Sbjct: 659 QLRTIGL 665 >3MI6-A nrPDB Length = 745 Score = 59.8 bits (143), Expect = 5e-09, Method: Composition-based stats. Identities = 83/548 (15%), Positives = 153/548 (27%), Gaps = 125/548 (22%) Query: 282 DLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAMDVVLQPSPALSWRSTGGILDVYI 341 + G NL S F A+E + L N + +P ++++ IL Y Sbjct: 243 EQGAVFGFNLVYSGNFLDAIEVDQYSTSRILTGINPDEFGWNLAPQATFQTPEAILS-YT 301 Query: 342 FLGPEPKSVVQQYLDVVGYPFMPPYWG-------LGFHLCRWGYSSTAITRQVVENMTRA 394 G + QQ + P + + + + A +V Sbjct: 302 SAG--MNQLSQQMASFYQQHLVNPRFAHEERPVLINNWEATYFDFNEAKLMTIVN--QAK 357 Query: 395 HFPLDVQWNDLDYMDSR-------RDFTFNKDGFRD-FPAMVQELHQGGRRYMMIVDP-A 445 +++ D + R D+ ++ F D Q +HQ G ++ + +P Sbjct: 358 RLGIEMFVLDDGWFGHRDDDTTSLGDWFVDQRKFPDGIEHFSQAVHQQGMKFGLWFEPEM 417 Query: 446 ISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVAE 505 +S P I P G+ D P + + ++++ Sbjct: 418 VSVDSDLYQQHP-------DWLIHAPKSTPTPGR----HQFVLDMARPEVVDYLFKLMSQ 466 Query: 506 FHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFL 565 + D + DMN Y + L + H+++ Sbjct: 467 MIESANLDYIKWDMN---------------------RYATEMFSSRLTSDQQLELPHRYI 505 Query: 566 STHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRY--------AGHWTGDV 617 Y L + P V+ S +G GR+ WT D Sbjct: 506 LGVYQL---------------YARLTQAYPNVLFESCASGGGRFDLGMMYYAPQAWTSDD 550 Query: 618 WSSWEQLASSV-------PEILQFNLLGVP---------LVGADVCGFLGNTSEEL---- 657 + E+L ++ ++ VP L F G+ EL Sbjct: 551 TDAAERLLIQFGTSYGYPQAMMGAHVSAVPNDQMGRITSLKTRGAVAFFGDLGYELDITK 610 Query: 658 ------------------CVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKAL 699 + Q G FY ++ + + ++A+ Sbjct: 611 MAPTELDQVKKQVAFYKCYRQLFQFGKFYRIDSPFVEDGNVTS--W---QVVSDDQKQAI 665 Query: 700 TLRYALLPHLYTLFHQAHVAGE-TVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQA 758 RY LL H + + + G R + D ST+ D L + +L Sbjct: 666 AARYQLLNHPNAPYTRFYFKGLRPNQR---YQINDDPSTYYGDE--LMNAGYFVPTILAD 720 Query: 759 GKAEVTGY 766 G+ Y Sbjct: 721 GQESKDFY 728 >5M0X-A nrPDB Length = 575 Score = 58.3 bits (139), Expect = 2e-08, Method: Composition-based stats. Identities = 39/249 (15%), Positives = 80/249 (32%), Gaps = 34/249 (13%) Query: 281 RDLAPTPGANLYG------SHPFYLALEDGGSAHGVFLLNSNAMDVVLQPSPALSWRSTG 334 D +YG +HPF+ + A+ + V L+P Sbjct: 125 SDYFVAEEGKVYGFLSSKIAHPFFAVEDGELVAYLEYFDVEFDDFVPLEP---------- 174 Query: 335 GILDVYIFLGPEPKSVVQQYLDVVGYP--FMPPYWGLGFHLCRWGYSSTAITRQVVENMT 392 + + P ++++Y ++VG P + Y + ++N+ Sbjct: 175 ----LVVLEDPNTPLLLEKYAELVGMENNARVPKHTPTGWCSWYHYFLDLTWEETLKNLK 230 Query: 393 -RAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPA-ISSSG 450 +FP +V D Y D+ + F M + + + G + P +S + Sbjct: 231 LAKNFPFEVFQIDDAYEKDIGDWLVTRGDFPSVEEMAKVIAENGFIPGIWTAPFSVSETS 290 Query: 451 PAGSYRPYDEGLRRGVFITNETGQPLIG-KVWPGSTAFPDFTNPTALAWWEDMVAEFHDQ 509 + P ++ E G+P + + W D + L W D+ + Sbjct: 291 DVFNEHPD--------WVVKENGEPKMAYRNWNKKIYALDLSKDEVLNWLFDLFSSLRK- 341 Query: 510 VPFDGMWID 518 + + ID Sbjct: 342 MGYRYFKID 350 >2YFN-A nrPDB Length = 720 Score = 47.5 bits (111), Expect = 3e-05, Method: Composition-based stats. Identities = 42/296 (14%), Positives = 87/296 (29%), Gaps = 54/296 (18%) Query: 265 SPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDG-----GSAHGVFLLNSNAMD 319 + + T + G + + +P + E G GS +G+ + S Sbjct: 199 HAMERNLERTPLGHGTIAFGSRRGTSSHQYNPAVILAEKGTTETAGSCYGMLFVYSGNFS 258 Query: 320 VVLQPS----PALSWRSTGGILDVYIFLGPE--PKSVVQQYLDVVGYPFMPPYW--GLGF 371 + L + + G V+ Y G + + + Sbjct: 259 CEAEKDQFNQTRLLLGLNEELFSYPLASGETFTVPEVILSYSAE-GLSALSQQYHNCIRN 317 Query: 372 HLCRWGY------------------SSTAITRQVVENMTRAHFPLDVQWNDLDYMD---- 409 H+CR Y + + + A +D+ D + Sbjct: 318 HVCRSKYVHMQRPVLINSWEAAYFDFTGDTIVDLAKE--AASLGIDMVVMDDGWFGKRND 375 Query: 410 ---SRRDFTFNKDGFRDFPA-MVQELHQGGRRYMMIVDP-AISSSGPAGSYRPYDEGLRR 464 S D+ N+ A ++ +H+ G ++ + ++P I+ YR + Sbjct: 376 DNSSLGDWQVNETKLGGSLAELITRVHEQGMKFGIWIEPEMINEDSDL--YRAH-----P 428 Query: 465 GVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPFDGMWIDMN 520 I + +P+ + + DF+ D + DQ D + DMN Sbjct: 429 DWAIRIQGKKPVRSR----NQLLLDFSRKEVRDCVFDQICVVLDQGKIDYVKWDMN 480 >2XN1-A nrPDB Length = 732 Score = 44.8 bits (104), Expect = 2e-04, Method: Composition-based stats. Identities = 31/269 (11%), Positives = 71/269 (26%), Gaps = 48/269 (17%) Query: 372 HLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSR-------RDFTFNKDGFRDF 424 + + + +V+ L++ D + R D+ K F + Sbjct: 340 WEATYFDFNEDKLKTIVD--KAKKLGLEMFVLDDGWFGHRDDDNSSLGDWKVYKKKFPNG 397 Query: 425 PA-MVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPG 483 +H+ G ++ + +P SY + +P + Sbjct: 398 LGHFADYVHEQGLKFGLWFEP------EMISYESNLYKEHPDYLMHVPGRKPCPSR---- 447 Query: 484 STAFPDFTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPY 543 + + + + + D D + DMN Sbjct: 448 NQYVLELGRKEVRDNIFEQMVKILDSKKIDYIKWDMN---------------------RS 486 Query: 544 VPGVVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTF 603 + + L A + H+++ +Y+L N + G F + ++ + Sbjct: 487 LSDIYESDLPADQQGEAYHRYVLGYYDLLNKLVTRYPDILFEGC--SGGGGRFDVGQAYY 544 Query: 604 AGHGRYAGHWTGDVWSSWEQLASSVPEIL 632 W D + E+L L Sbjct: 545 T-----PQIWASDNTDAIERLKIQYGTSL 568 >1HI7-A nrPDB Length = 60 Score = 42.8 bits (99), Expect = 7e-04, Method: Composition-based stats. Identities = 18/52 (34%), Positives = 24/52 (46%), Gaps = 10/52 (19%) Query: 82 CDVPPNSRFDC-APDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFPPS 132 C V P R +C P +T QC +GCC+ G PWCF+P + Sbjct: 7 CTVAPRERQNCGFP--GVTPSQCANKGCCFD-------DTVRGVPWCFYPNT 49 >2AAA-A nrPDB Length = 484 Score = 40.5 bits (93), Expect = 0.004, Method: Composition-based stats. Identities = 34/177 (19%), Positives = 55/177 (31%), Gaps = 17/177 (9%) Query: 407 YMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDP---AISSSGPAGSYRPYDEGLR 463 + D N + ++ LH G M+ V P + +G Y +D Sbjct: 83 WQQKIYDVNSNFGTADNLKSLSDALHARGMYLMVDVVPDHMGYAGNGNDVDYSVFDPFDS 142 Query: 464 RGVF-----ITNETGQPLIGKVWPGST--AFPDF--TNPTALAWWEDMVAEFHDQVPFDG 514 F IT+ ++ W G T + PD T W D VA+ DG Sbjct: 143 SSYFHPYCLITDWDNLTMVEDCWEGDTIVSLPDLDTTETAVRTIWYDWVADLVSNYSVDG 202 Query: 515 MWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNL 571 + ID + + D P + Y G + A+ +Y + Sbjct: 203 LRID-----SVLEVQPDFFPGYNKASGVYCVGEIDNGNPASDCPYQKVLDGVLNYPI 254 >4GKL-A nrPDB Length = 422 Score = 40.2 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 14/100 (14%), Positives = 34/100 (34%), Gaps = 10/100 (10%) Query: 423 DFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRG--VFITNETGQPLIGKV 480 DF V+ H+ ++ + + +++ F+ +E G P Sbjct: 80 DFKKFVKRAHE--------LNMYVLMDMVLNHAAVDNVLVKKHPEWFLRDENGNPTRKVP 131 Query: 481 WPGSTAFPDFTNPTALAWWEDMVAEFHDQVPFDGMWIDMN 520 D++N + +M+ + ++ DG D+ Sbjct: 132 DWSDVVDFDYSNGELREYMINMMRYWVEEFDVDGFRCDVA 171 >1PSP-A nrPDB Length = 106 Score = 39.8 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 17/67 (25%) Query: 72 PGRP---RAVPTQ----CDVPPNSRFDC-APDKAITQEQCEARGCCYIPAKQGLQGAQMG 123 PG P + +P Q C + ++R +C P I+ E C AR CC+ Sbjct: 41 PGVPWCFKPLPAQESEECVMQVSARKNCGYP--GISPEDCAARNCCF-------SDTIPE 91 Query: 124 QPWCFFP 130 PWCFFP Sbjct: 92 VPWCFFP 98 Score = 38.6 bits (88), Expect = 0.012, Method: Composition-based stats. Identities = 20/58 (34%), Positives = 24/58 (41%), Gaps = 11/58 (18%) Query: 74 RPRAVPTQCDVPPNSRFDC-APDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFP 130 +P A P N R +C P IT +QC GCC+ G PWCF P Sbjct: 2 KPAACRCSRQDPKN-RVNCGFP--GITSDQCFTSGCCFD-------SQVPGVPWCFKP 49 >5OT1-A nrPDB Length = 765 Score = 39.4 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 21/124 (16%), Positives = 40/124 (32%), Gaps = 16/124 (12%) Query: 409 DSRRDFTFNKD--GFRDFPAMVQELHQGGRRYMM--------IVDPAISSSGPAGSYRP- 457 D+ + + + + E H+ G R + I +PA G+ P Sbjct: 384 DTYDYYRLDPKFGTEDELREFLDEAHRRGMRVIFDFVPNHCGIGNPAFLDVWEKGNESPY 443 Query: 458 YDEGLRRGVFITNETGQPLIGKVWPGSTAFPDF--TNPTALAWWEDMVAEFHDQVPFDGM 515 +D + G +G W G + P N + + + FDG+ Sbjct: 444 WDWFFVKKWPFKLGDGSAYVG--WWGFGSLPKLNTANQEVREYLIGAALHWIE-FGFDGI 500 Query: 516 WIDM 519 +D+ Sbjct: 501 RVDV 504 >5MX0-A nrPDB Length = 362 Score = 38.6 bits (88), Expect = 0.015, Method: Composition-based stats. Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 18/72 (25%) Query: 41 ELSGSSPVLEETHPAHQQGASRPGPRDAQAHPGRPRAVPTQCDVPPNSRFDCAPDKAITQ 100 E S SP + PA G+ P P D PR P +CD PPN T Sbjct: 34 ETSEPSPSGVDEGPASTSGS--PSPPD-------PRDCPQECDCPPN---------FPTA 75 Query: 101 EQCEARGCCYIP 112 C+ R Y+P Sbjct: 76 MYCDNRNLKYLP 87 >5A2B-A nrPDB Length = 497 Score = 38.2 bits (87), Expect = 0.016, Method: Composition-based stats. Identities = 18/135 (13%), Positives = 40/135 (29%), Gaps = 18/135 (13%) Query: 391 MTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSG 450 W + Y T + DF +V+E H+ + ++ + Sbjct: 101 FANEKGGYHGYWIEDFYKVEEHFGTLD-----DFKRLVKEAHKRDMKVIL----DFVVNH 151 Query: 451 PAGSYRPYDEGLRRGVFITNETGQPLIGK-----VWPGSTAFPDFT--NPTALAWWEDMV 503 ++ ++ ++ F + + W PD NP + D+ Sbjct: 152 TGYNHPWLNDPAKKDWFHEKKDIFNWANQQEVENGWLF--GLPDLAQENPEVKTYLFDVA 209 Query: 504 AEFHDQVPFDGMWID 518 + + DG +D Sbjct: 210 KWWIQETDIDGYRLD 224 >3WY1-A nrPDB Length = 538 Score = 38.2 bits (87), Expect = 0.017, Method: Composition-based stats. Identities = 39/208 (18%), Positives = 62/208 (29%), Gaps = 50/208 (24%) Query: 394 AHFPLDVQWNDLDYMDSRRDFTFNKDGFR----------DFPAMVQELHQGGRRYMMIVD 443 A +D W + DF ++ +R DF A++++ H G + M +D Sbjct: 43 ASLNVDGIWLSPFFTSPMLDFGYDVSDYRDVDPMFGTLEDFKALLEKAHSLGLKVM--ID 100 Query: 444 PAISSSGPAGSYRPYDEGLR----RGVFI---TNETGQP-------LIGKVWPGS----- 484 IS + + R F+ G P G W Sbjct: 101 QVISHTSDQHPWFQESRQNRTNPKADWFVWADPKPDGTPPNNWLSIFGGSAWTFDSRRQQ 160 Query: 485 -------TAFPD--FTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPN 535 T+ PD F +P A Q+ W+D+ + + Sbjct: 161 YYLHNFLTSQPDVNFHHPEARQ----------AQLDNMRFWLDLGVDGFRLDTVNFYFHD 210 Query: 536 NELENPPYVPGVVGGTLQAATICASSHQ 563 EL + P VP TL A + Q Sbjct: 211 AELRDNPPVPKGEAKTLGAPEANPYTWQ 238 >6JEQ-A nrPDB Length = 675 Score = 37.5 bits (85), Expect = 0.026, Method: Composition-based stats. Identities = 26/242 (10%), Positives = 69/242 (28%), Gaps = 42/242 (17%) Query: 412 RDFTFNKDGFRDFPA------------------MVQELHQGGRRYMMIVDPAISSSGPAG 453 ++ ++ + ++Q+LH G R +M + + Sbjct: 232 YNWGYDPQNYNVPEGSYSTDPHNPAARILELKRLIQKLHARGLRVIM----DVVYNHVYD 287 Query: 454 SYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPFD 513 Y + L G ++ + + + G+ + P + + + + + D Sbjct: 288 GYLIHFTKLVPGYYLRYKADRTFSDGTFCGNECASE--RPIMRKYIIESILHWVREYHID 345 Query: 514 GMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHN 573 G D+ + +E +E++ P + + G + + L Sbjct: 346 GFRFDLMGMIDIETMNEIRRRLDEID--PTILTIGEGWMMETVLPKELRANQDNAEKLPG 403 Query: 574 LYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQ 633 + + + A F+ R F GD + + + V + Sbjct: 404 IGMFNDGM------RDAVKGDIFIFDRKGFIS--------GGDGFE--DGVKRGVAGGIN 447 Query: 634 FN 635 + Sbjct: 448 YG 449 >2E8Y-A nrPDB Length = 718 Score = 36.7 bits (83), Expect = 0.046, Method: Composition-based stats. Identities = 24/141 (17%), Positives = 46/141 (32%), Gaps = 28/141 (19%) Query: 399 DVQWNDLDYMDSRRDFTFNKDGFRDF------------------PAMVQELHQGGRRYMM 440 D D + ++ +N F M+ LHQ G R ++ Sbjct: 275 DFAGVDEEKPLDAYNWGYNPLHFFAPEGSYASNPHDPQTRKTELKQMINTLHQHGLRVIL 334 Query: 441 IVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPT--ALAW 498 V + + P+++ + F +E G+P G+ D + A + Sbjct: 335 DV---VFNHVYKRENSPFEKTVPGYFFRHDECGKPSN-----GTGVGNDIASERRMARKF 386 Query: 499 WEDMVAEFHDQVPFDGMWIDM 519 D V + ++ DG D+ Sbjct: 387 IADCVVYWLEEYNVDGFRFDL 407 >4CGT-A nrPDB Length = 678 Score = 36.7 bits (83), Expect = 0.054, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 42/108 (38%), Gaps = 13/108 (12%) Query: 423 DFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETG--------- 473 DF ++ H G + ++ P +S A + R YD G G + + G Sbjct: 117 DFQNLITTAHAKGIKIVIDFAPNHTSPADAENGRLYDNGTLVGGYTNDTNGYFHHNGGSD 176 Query: 474 -QPLIGKVWPGSTAFPDFTNPTAL--AWWEDMVAEFHDQVPFDGMWID 518 L ++ DF + A +++D + + D + DG+ +D Sbjct: 177 FSSLENGIYKNLYDLADFNHNNATIDKYFKDAIKLWLD-MGVDGIRVD 223 >5BRQ-A nrPDB Length = 568 Score = 35.5 bits (80), Expect = 0.097, Method: Composition-based stats. Identities = 28/175 (16%), Positives = 52/175 (29%), Gaps = 38/175 (21%) Query: 382 AITRQVVENMT-RAHFPLDVQWNDLDYMDSRRDFTFNKDGF----------RDFPAMVQE 430 R ++E + DV W Y + D ++ + DF +++E Sbjct: 37 GDIRGIIEKLDYIKELACDVIWLTPIYQSPQNDNGYDISDYYSIHEEYGTMADFEELLEE 96 Query: 431 LHQGGRRYM--MIVDPAISSSGPAGSYRPYDEGLRRGVFI---TNETGQP-------LIG 478 H+ G + + ++V+ + E L R +I G P G Sbjct: 97 AHKRGIKVIMDLVVNHTSTEHRWFKEAASGKENLYRDFYIWKDMKPNGAPPTNWESKFGG 156 Query: 479 KVWPGST-------AFPDFT-------NPTALAWWEDMVAEFHDQVPFDGMWIDM 519 W D T N +M+ + + DG +D+ Sbjct: 157 SAWEFHAESGQYYLHLYDVTQADLNWENEAVRKKVYEMMHFWFE-KGIDGFRLDV 210 >1LWJ-A nrPDB Length = 441 Score = 35.5 bits (80), Expect = 0.12, Method: Composition-based stats. Identities = 23/137 (16%), Positives = 38/137 (27%), Gaps = 28/137 (20%) Query: 410 SRRDFTFNKDGFRDFPAMVQELHQGGRRYMM------------IVDPAISSSGPAGSYRP 457 F R+F M++ H G + ++ A+ Y Sbjct: 58 DFYSFKAEYGSEREFKEMIEAFHDSGIKVVLDLPIHHTGFLHTWFQKALKGDPHYRDYYV 117 Query: 458 YD----------EGLRRGVFITNETGQPLIGKVWPGSTAFPDFT--NPTALAWWEDMVAE 505 + E ++ E G+ G P S PD NP + +V Sbjct: 118 WANKETDLDERREWDGEKIWHPLEDGRFYRGLFGPFS---PDLNYDNPQVFDEMKRLVLH 174 Query: 506 FHDQVPFDGMWIDMNEP 522 D + DG D + Sbjct: 175 LLD-MGVDGFRFDAAKH 190 >2VNC-A nrPDB Length = 718 Score = 35.1 bits (79), Expect = 0.16, Method: Composition-based stats. Identities = 15/126 (11%), Positives = 36/126 (28%), Gaps = 19/126 (15%) Query: 413 DFTFNKDGFRDF-----------------PAMVQELHQGGRRYMM-IVDPAISSSGPAGS 454 + ++ F MV ELH G ++ +V + G Sbjct: 241 YWGYDPINFFSPECRYSSTGCLGGQVLSFKKMVNELHNAGIEVIIDVVYNHTAEGNHLGP 300 Query: 455 YRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPFDG 514 + ++ + G+ + ++P + D + + ++ DG Sbjct: 301 TLSFRGIDNTAYYMLQPDNKRYYLDF-TGTGNTLNLSHPRVIQMVLDSLRYWVTEMHVDG 359 Query: 515 MWIDMN 520 D+ Sbjct: 360 FRFDLA 365 >5GSL-A nrPDB Length = 778 Score = 34.8 bits (78), Expect = 0.19, Method: Composition-based stats. Identities = 19/115 (16%), Positives = 38/115 (33%) Query: 400 VQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYD 459 + WN + + DFT RD ++ + G ++ P I G + Sbjct: 56 IAWNWHEPQEGVFDFTGETHPQRDLIGFLELAQKLGLYVIIRPGPYICGEWKNGGIPDWL 115 Query: 460 EGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPFDG 514 + + G +P T A+ W+E+++ D + +G Sbjct: 116 INSHPEILAKSPNGSFPRDVYYPPITYLHPTYLEYAMKWYEEVLPIIRDYLYSNG 170 >3EYP-A nrPDB Length = 469 Score = 34.8 bits (78), Expect = 0.21, Method: Composition-based stats. Identities = 17/135 (12%), Positives = 39/135 (28%), Gaps = 13/135 (9%) Query: 383 ITRQVVENMTRAHFPLDVQ---WND--LDYMDSRRDFTFNKDGFRDFPA-----MVQELH 432 RQ ++ + A P + D + D++ +++ V Sbjct: 55 DCRQWMQTLKAAGIPAAILTAKHADGFCLWPSKYTDYSVKNAAWKNGKGDVVREFVDACE 114 Query: 433 QGGRRYMMIVDPAISSS--GPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDF 490 + G + + + P P + Y E + I + W + Sbjct: 115 EYGLKAGIYLGPHDRHEHLSPLYTTERYKEYYAHQLGELMSDYGK-IWETWWDGAGADEL 173 Query: 491 TNPTALAWWEDMVAE 505 T P W++ + + Sbjct: 174 TTPVYRHWYKIVREK 188 >4NZJ-A nrPDB Length = 477 Score = 34.4 bits (77), Expect = 0.27, Method: Composition-based stats. Identities = 19/125 (15%), Positives = 42/125 (33%), Gaps = 14/125 (11%) Query: 350 VVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMD 409 V++ +++ P M W + + + Q + M D+ ++ ++ D Sbjct: 89 VIRIGDELLLTPPM--GWN--SWNTFGQHLTEELVLQTADAMITNGMR-DLGYSYINIDD 143 Query: 410 SRRD--------FTFNKDGFRDFPAMVQE-LHQGGRRYMMIVDPAISSSGPAGSYRPYDE 460 + +K F V + LH+ G + + D A + G Y+E Sbjct: 144 FWQLPERGADGHLQIDKTKFPRGIKYVADYLHERGFKLGIYSDAAEKTCGGVCGSYGYEE 203 Query: 461 GLRRG 465 + Sbjct: 204 TDAKD 208 >1Z9L-A nrPDB Length = 128 Score = 34.0 bits (76), Expect = 0.32, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 39/94 (41%), Gaps = 3/94 (3%) Query: 162 KDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETPHVHSRAPSPLYSVEFSEEPFGVI 221 D++T L + ++ ++ F +K A RRY V P+ P + +V +PF Sbjct: 26 TDVVTTNLKLQNPSDRKVCFKVKTTAPRRYCV---RPNSGVIDPGSIVTVSVMLQPFDYD 82 Query: 222 VRRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQ 255 + + ++ T AP +D + P + Sbjct: 83 PNEKSKHKFMVQTIFAPPNISDMEAVWKEAKPDE 116 >5WCZ-A nrPDB Length = 586 Score = 34.0 bits (76), Expect = 0.37, Method: Composition-based stats. Identities = 27/166 (16%), Positives = 49/166 (29%), Gaps = 45/166 (27%) Query: 394 AHFPLDVQWN-------------DL-DYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYM 439 + DV W D+ DY + F N+D F ++ E+H+ G + + Sbjct: 65 KNLGADVIWLSPVFDSPQDDNGYDISDYKNMYEKFGTNEDMF----QLIDEVHKRGMKIV 120 Query: 440 -------------MIVDPAISSSGPAGSYRPYD----EGLRRGVFITNETGQPLIGKVWP 482 + S P Y + +G + + +G Sbjct: 121 MDLVVNHTSDEHAWFAESRKSKDNPYRDYYLWKDPKPDGSEPNNWGSIFSGSAWTYDEGT 180 Query: 483 GSTAF-------PDFT--NPTALAWWEDMVAEFHDQVPFDGMWIDM 519 G PD N D++ + D+ DG +D+ Sbjct: 181 GQYYLHYFSKKQPDLNWENEAVRREVYDVMRFWMDR-GVDGWRMDV 225 >5BXR-A nrPDB Length = 644 Score = 33.6 bits (75), Expect = 0.37, Method: Composition-based stats. Identities = 13/113 (11%), Positives = 38/113 (33%), Gaps = 16/113 (14%) Query: 409 DSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFI 468 ++++ T++ D V++ + G + ++ + +Y Y G Sbjct: 206 NTKKAATWSYYTRDDVKKFVKKANNYGIDVIPEINSPGHMNVWLENYPEYQLADNSGR-- 263 Query: 469 TNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPFDGMWIDMNE 521 + D +NP A+ +++ ++ E+ + +E Sbjct: 264 KDPNK--------------LDISNPEAVKFYKTLIDEYDGVFTTKYWHMGADE 302 >2CRI-A nrPDB Length = 147 Score = 33.6 bits (75), Expect = 0.39, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 39/94 (41%), Gaps = 3/94 (3%) Query: 162 KDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETPHVHSRAPSPLYSVEFSEEPFGVI 221 D++T L + ++ ++ F +K A RRY V P+ P + +V +PF Sbjct: 30 TDVVTTNLKLQNPSDRKVCFKVKTTAPRRYCV---RPNSGIIDPGSIVTVSVMLQPFDYD 86 Query: 222 VRRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQ 255 + + ++ T AP +D + P + Sbjct: 87 PNEKSKHKFMVQTIFAPPNISDMEAVWKEAKPDE 120 >1EHA-A nrPDB Length = 558 Score = 33.6 bits (75), Expect = 0.39, Method: Composition-based stats. Identities = 27/187 (14%), Positives = 67/187 (35%), Gaps = 30/187 (16%) Query: 347 PKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLD 406 P ++Q+ + F+ + + + ++ V+ + + D+ ++ Sbjct: 81 PSQIIQESKEFNNETFLKKEDLIIYEIHVGTFTPEGTFEGVI---RKLDYLKDLGITAIE 137 Query: 407 YMD-----SRRDFTFN-------KDGFRDFPAM---VQELHQGGRRYMMIVDPAISSSGP 451 M +RD+ ++ ++ + V E H+ G +I+D + GP Sbjct: 138 IMPIAQFPGKRDWGYDGVYLYAVQNSYGGPEGFRKLVDEAHKKG--LGVILDVVYNHVGP 195 Query: 452 AGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVP 511 G+Y ++ G + + + P W + F D + + + V + + Sbjct: 196 EGNY-----MVKLGPYFSQKYKTP-----WGLTFNFDDAESDEVRKFILENVEYWIKEYN 245 Query: 512 FDGMWID 518 DG +D Sbjct: 246 VDGFRLD 252 >5MDX-4 nrPDB Length = 210 Score = 33.6 bits (75), Expect = 0.44, Method: Composition-based stats. Identities = 26/129 (20%), Positives = 41/129 (31%), Gaps = 16/129 (12%) Query: 402 WNDLDYMDSR--RDFTFNKDGFRDFPAMVQELHQ----GGRRYMMIVDPAISSSGPAGSY 455 + D +++D DF F+ G PA ++ + GR M V I Sbjct: 20 FLDPEWLDGSLPGDFGFDPLGLGKDPAFLKWYREAELIHGRWAMAAVL-GIFVGQAWSGV 78 Query: 456 RPYDEGLRRGVFITNETGQPL----IGKVWPGSTAFPDFTNPTAL--AW---WEDMVAEF 506 ++ G + G L + W S + DF NP + W W F Sbjct: 79 AWFEAGAQPDAIAPFSFGSLLGTQLLLMGWVESKRWVDFFNPDSQSVEWATPWSKTAENF 138 Query: 507 HDQVPFDGM 515 + G Sbjct: 139 ANYTGDQGY 147 >5XNL-4 nrPDB Length = 210 Score = 33.2 bits (74), Expect = 0.52, Method: Composition-based stats. Identities = 27/127 (21%), Positives = 39/127 (30%), Gaps = 16/127 (12%) Query: 404 DLDYMDSR--RDFTFNKDGFRDFPAMVQELHQ----GGRRYMMIVDPAISSSGPAGSYRP 457 D +++D DF F+ G PA ++ + GR M V I Sbjct: 21 DPEWLDGSLPGDFGFDPLGLGKDPAFLKWYREAELIHGRWAMAAVL-GIFVGQAWSGVPW 79 Query: 458 YDEGLRRGVFITNETGQPL----IGKVWPGSTAFPDFTNPTAL--AW---WEDMVAEFHD 508 ++ G G L I W S + DF NP + W W F + Sbjct: 80 FEAGADPNAIAPFSFGTLLGTQLILMGWVESKRWVDFFNPDSQSVEWATPWSKTAENFVN 139 Query: 509 QVPFDGM 515 G Sbjct: 140 STGEQGY 146 >4OGZ-A nrPDB Length = 473 Score = 33.2 bits (74), Expect = 0.53, Method: Composition-based stats. Identities = 20/119 (16%), Positives = 36/119 (30%), Gaps = 14/119 (11%) Query: 356 DVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFP--------LDVQWNDLDY 407 +++ P M W + + + Q + M +D W L Sbjct: 95 ELLLTPPM--GWN--SWNTFGRHLTEELLLQTADAMVENGMRDLGYAYINIDDFWQ-LPE 149 Query: 408 MDSRRDFTFNKDGFRDFPAMVQE-LHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRG 465 + +K F V + LH+ G + + D A + G Y+E R Sbjct: 150 RGADGHIQIDKTKFPRGIKYVADYLHERGFKLGIYSDAADKTCGGVCGSYGYEEIDARD 208 >5M99-B nrPDB Length = 505 Score = 32.8 bits (73), Expect = 0.74, Method: Composition-based stats. Identities = 26/207 (12%), Positives = 58/207 (28%), Gaps = 34/207 (16%) Query: 377 GYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGF----------RDFPA 426 G Q V+ + + D W + + ++ ++ + D Sbjct: 22 GVGDINGVSQKVDYLRKLGI--DAVWF-MPFNEAVSYHGYDITDYYNVEKDYGTMEDLEN 78 Query: 427 MVQELHQGGRRYM--MIVD------PAISSSGPAGSYRPY---------DEGLRRGVFIT 469 M+Q LH+ G + + ++++ P + + PY D + Sbjct: 79 MIQVLHENGIKVIMDLVINHTSDEHPWFKDAVENTTSSPYWDYYIMSLEDHSGQDHWHWK 138 Query: 470 NETGQPLIGKVWPGSTAFPDFT--NPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIR 527 + + PD + + +F DG ID + + Sbjct: 139 INSKGQKVWYFGLFGYNMPDLNHDSQKVRE-EVKKIVDFWISKGVDGFRIDAAKH-IYGW 196 Query: 528 GSEDGCPNNELENPPYVPGVVGGTLQA 554 +DG + + V+ A Sbjct: 197 SWDDGIQESAEYFEWFRDYVLSKKPDA 223 >3K1D-A nrPDB Length = 722 Score = 32.8 bits (73), Expect = 0.80, Method: Composition-based stats. Identities = 29/163 (17%), Positives = 45/163 (27%), Gaps = 26/163 (15%) Query: 369 LGFHLCRWGYSSTAITRQVVENMTRAHF-----------PLDVQWNDLDYMDSRRDFTFN 417 LG Y A R++ + + F P W Y + + Sbjct: 253 LGSWRPGLSYRQLA--RELTDYIVDQGFTHVELLPVAEHPFAGSW---GYQVTSYYAPTS 307 Query: 418 KDGFRD-FPAMVQELHQGGRRYMM-IVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQP 475 + G D F A+V LHQ G ++ V A P Sbjct: 308 RFGTPDDFRALVDALHQAGIGVIVDWVPAHFPKDAWALGRFDGTPLYEHS--------DP 359 Query: 476 LIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPFDGMWID 518 G+ T DF P + + + DG+ +D Sbjct: 360 KRGEQLDWGTYVFDFGRPEVRNFLVANALYWLQEFHIDGLRVD 402 >3AWQ-A nrPDB Length = 415 Score = 32.1 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 26/74 (35%), Gaps = 5/74 (6%) Query: 410 SRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFIT 469 + +DF + F + +V +L+ DP +R +DE FI Sbjct: 295 ASQDFEWEGMAFPEGRQVVLDLYGSNHDAATWADP---QEFRPERFRAWDEDSFN--FIP 349 Query: 470 NETGQPLIGKVWPG 483 G +G PG Sbjct: 350 QGGGDHYLGHRCPG 363 >1AKN-A nrPDB Length = 579 Score = 32.1 bits (71), Expect = 1.2, Method: Composition-based stats. Identities = 36/204 (17%), Positives = 67/204 (32%), Gaps = 19/204 (9%) Query: 636 LLGVPLVGADVCGFLGN----TSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPA 691 + G VG DV N T E+ + L +R N+ + EP++ Sbjct: 319 MDGHLFVGMDVPAINSNKQDVTEEDFYKLVSGLTV-TKGLRGANATYEVYTEPWAQDSSQ 377 Query: 692 QQAMRKALTLRYA---LLPHLYTLF-HQAHVAGETVARPLFLE------FPKDSSTWTVD 741 + + + L L+P + H++H LF + +PK D Sbjct: 378 ETRKKTMVDLETDILFLIPTKIAVAQHKSHAKSANTYTYLFSQPSRMPIYPKWMGADHAD 437 Query: 742 H-QLLWGEALLITPV-LQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIH 799 Q ++G+ TP+ +A V+ + W + G P Sbjct: 438 DLQYVFGKPF-ATPLGYRAQDRTVSKAM-IAYWTNFARTGDPNTGHSTVPANWDPYTLED 495 Query: 800 SEGQWVTLPAPLDTINVHLRAGYI 823 + +++ +HLR Y+ Sbjct: 496 DNYLEINKQMDSNSMKLHLRTNYL 519 >2WSK-A nrPDB Length = 657 Score = 31.7 bits (70), Expect = 1.6, Method: Composition-based stats. Identities = 16/105 (15%), Positives = 35/105 (33%), Gaps = 4/105 (3%) Query: 417 NKDGFRDFPAMVQELHQGGRRYMM-IVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQP 475 + +F ++ LH+ G ++ IV + G R + E G Sbjct: 237 PETALDEFRDAIKALHKAGIEVILDIVLNHSAELDLDGPLFSLRGIDNRSYYWIREDG-D 295 Query: 476 LIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPFDGMWIDMN 520 G+T + ++P + + + + + DG D+ Sbjct: 296 YHNWTGCGNT--LNLSHPAVVDYASACLRYWVETCHVDGFRFDLA 338 >5X7U-A nrPDB Length = 549 Score = 30.5 bits (67), Expect = 3.3, Method: Composition-based stats. Identities = 21/156 (13%), Positives = 41/156 (26%), Gaps = 32/156 (20%) Query: 394 AHFPLDVQWNDLDYMDSRRDFTFNKDGFR----------DFPAMVQELHQGGRRYM---- 439 + W Y +D ++ +R DF + E H+ G R + Sbjct: 43 ESLGVTAIWLLPFYASPLKDGGYDISDYRSLHPDFGTIEDFKVFLDEAHRRGIRVITELV 102 Query: 440 ---------MIVDPAISSSGPAGSYRPY----DEGLRRGVFITNETGQPLIGKVWPGSTA 486 + + + P Y + D+ + + G Sbjct: 103 LNHTSDQHQWFREARSNPNSPYRDYYVWSDTDDKYKDARIIFIDTERSNWTWDQEAGKYY 162 Query: 487 FPDFTN--PTALAWWEDMVAEFHDQVPFDGMWIDMN 520 + F + P D + + G W+DM Sbjct: 163 WHRFFSHQPDLN---YDNPKVQQEILDIVGYWLDMG 195 >5FA5-B nrPDB Length = 367 Score = 30.5 bits (67), Expect = 3.6, Method: Composition-based stats. Identities = 10/44 (22%), Positives = 13/44 (29%), Gaps = 4/44 (9%) Query: 63 PGPRDAQAHPGRPRAVPTQCDVPPNSRFDCAPDKAITQEQCEAR 106 P + + P VPP +R P A C R Sbjct: 15 PTTENLYFQGSLRKETPPPL-VPPAAREWNLPPNAPA---CMER 54 >3ATQ-A nrPDB Length = 453 Score = 30.1 bits (66), Expect = 4.1, Method: Composition-based stats. Identities = 10/63 (15%), Positives = 22/63 (34%), Gaps = 1/63 (1%) Query: 768 PLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAP-LDTINVHLRAGYIIPL 826 P G W+ + L +++ AP +D + ++ G ++P Sbjct: 213 PGGYWWYFPKGKNKVNVGLGIQGGMGYPSIHEYYKKYLDKYAPDVDKSKLLVKGGALVPT 272 Query: 827 QGP 829 + P Sbjct: 273 RRP 275 >4PNG-A nrPDB Length = 229 Score = 30.1 bits (66), Expect = 4.3, Method: Composition-based stats. Identities = 11/64 (17%), Positives = 24/64 (37%) Query: 192 EVPLETPHVHSRAPSPLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPLFFADQFLQLSTS 251 EVP E V++RA + P + + DG + ++ + ++ + + Sbjct: 32 EVPYEFVEVNTRAKENFSEEFLKKNPQHTVPTLEDDGHYIWDSHAIIAYLVSKYGKTDSL 91 Query: 252 LPSQ 255 P Sbjct: 92 YPKD 95 >5GSM-A nrPDB Length = 786 Score = 30.1 bits (66), Expect = 4.3, Method: Composition-based stats. Identities = 12/127 (9%), Positives = 30/127 (23%), Gaps = 3/127 (2%) Query: 380 STAITRQVVENMTRAHFPLDVQWNDLDYMD-SRRDFTFNKDGFRD--FPAMVQELHQGGR 436 + + M A + ++ + + F F + ++ + G Sbjct: 31 PADAWKDRLLKMREAGLNTVDTYVAWNWHEPEKGSFDFKGETHPQRNLVGFLELADELGF 90 Query: 437 RYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTAL 496 ++ P I G + + G +P T Sbjct: 91 YVIIRPGPYICGEWRNGGIPDWLIDEHPEILAKGPNGPLPRDIYYPPITYLHPTYLEAVG 150 Query: 497 AWWEDMV 503 W+ + Sbjct: 151 EWYNAVF 157 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.125 0.350 Lambda K H 0.267 0.0383 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 36,188,015 Number of Sequences: 36641 Number of extensions: 1488495 Number of successful extensions: 4153 Number of sequences better than 10.0: 63 Number of HSP's better than 10.0 without gapping: 50 Number of HSP's successfully gapped in prelim test: 43 Number of HSP's that attempted gapping in prelim test: 3746 Number of HSP's gapped (non-prelim): 119 length of query: 952 length of database: 10,336,785 effective HSP length: 106 effective length of query: 846 effective length of database: 6,452,839 effective search space: 5459101794 effective search space used: 5459101794 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 64 (29.4 bits)