BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P10144 (247 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1IAU-A nrPDB 479 e-136 1FI8-A nrPDB 337 3e-93 3TK9-A nrPDB 328 1e-90 1EUF-A nrPDB 288 1e-78 3G01-A nrPDB 286 5e-78 1KYN-A nrPDB 258 2e-69 1NN6-A nrPDB 232 1e-61 3RP2-A nrPDB 209 1e-54 2RDL-A nrPDB 199 7e-52 1ORF-A nrPDB 163 5e-41 1UTJ-A nrPDB 162 2e-40 1FDP-A nrPDB 151 3e-37 5FXL-A nrPDB 149 8e-37 5FCR-A nrPDB 149 2e-36 1FUJ-A nrPDB 148 2e-36 1A0J-A nrPDB 147 3e-36 4AN7-A nrPDB 146 1e-35 4Q7Y-A nrPDB 145 2e-35 1F7Z-A nrPDB 145 2e-35 2ZKS-A nrPDB 142 2e-34 1MZD-A nrPDB 140 4e-34 4WWY-A nrPDB 140 5e-34 5MS3-A nrPDB 140 5e-34 1SGF-G nrPDB 137 4e-33 1NPM-A nrPDB 135 1e-32 2TLD-E nrPDB 135 2e-32 1SPJ-A nrPDB 135 2e-32 2EEK-A nrPDB 134 3e-32 5C67-A nrPDB 132 2e-31 4NFE-A nrPDB 130 4e-31 1TON-A nrPDB 130 4e-31 1SGF-A nrPDB 130 7e-31 5ZFH-A nrPDB 126 8e-30 2BDH-A nrPDB 125 1e-29 1AO5-A nrPDB 124 5e-29 3BSQ-A nrPDB 124 5e-29 2PSX-A nrPDB 122 1e-28 1AZZ-A nrPDB 122 2e-28 4DGJ-A nrPDB 121 3e-28 6QHB-A nrPDB 120 6e-28 1GVZ-A nrPDB 120 7e-28 1PPF-E nrPDB 119 1e-27 3QUM-P nrPDB 117 4e-27 2R0L-A nrPDB 115 2e-26 1YC0-A nrPDB 114 3e-26 1EKB-B nrPDB 114 4e-26 1AE5-A nrPDB 114 4e-26 1FXY-A nrPDB 113 8e-26 3W94-A nrPDB 112 1e-25 5UGG-A nrPDB 112 1e-25 2V35-A nrPDB 111 3e-25 2AIQ-A nrPDB 110 6e-25 1X7A-C nrPDB 109 1e-24 1BRU-P nrPDB 109 1e-24 4DUR-A nrPDB 108 2e-24 2CGA-A nrPDB 108 3e-24 1ELT-A nrPDB 107 4e-24 4MPW-A nrPDB 107 5e-24 1EQ9-A nrPDB 107 6e-24 1LTO-A nrPDB 107 7e-24 3E0N-B nrPDB 104 3e-23 1P57-B nrPDB 104 3e-23 3T2N-A nrPDB 104 4e-23 1PYT-D nrPDB 104 4e-23 3LC3-A nrPDB 104 4e-23 3DFJ-A nrPDB 103 7e-23 2F91-A nrPDB 103 8e-23 4GSO-A nrPDB 102 1e-22 4H4F-A nrPDB 101 3e-22 4E7N-A nrPDB 99 2e-21 5XW8-A nrPDB 97 6e-21 5TJX-A nrPDB 97 6e-21 3S69-A nrPDB 97 9e-21 4XDE-A nrPDB 96 1e-20 2QY0-B nrPDB 96 1e-20 5GVT-A nrPDB 96 1e-20 6I44-A nrPDB 96 2e-20 5LHN-A nrPDB 94 4e-20 1GPZ-A nrPDB 94 5e-20 2F83-A nrPDB 94 7e-20 1MD7-A nrPDB 93 8e-20 3S9B-A nrPDB 93 9e-20 1SC8-U nrPDB 93 9e-20 6AOD-C nrPDB 93 1e-19 2XXL-A nrPDB 93 1e-19 2OLG-A nrPDB 92 2e-19 1A5I-A nrPDB 91 4e-19 1BDA-A nrPDB 91 5e-19 1OP0-A nrPDB 91 5e-19 3P8G-A nrPDB 91 6e-19 3F6U-H nrPDB 90 7e-19 1FIW-A nrPDB 90 8e-19 1FIZ-A nrPDB 90 1e-18 2HLC-A nrPDB 89 1e-18 2ASU-B nrPDB 89 2e-18 2OQ5-A nrPDB 89 2e-18 5KWM-A nrPDB 88 3e-18 1FON-A nrPDB 88 4e-18 1KIG-H nrPDB 87 4e-18 5LPF-A nrPDB 87 7e-18 4IGD-A nrPDB 85 2e-17 1C5M-D nrPDB 85 3e-17 4DJZ-B nrPDB 84 4e-17 5O32-I nrPDB 84 5e-17 1BQY-A nrPDB 84 5e-17 1SI5-H nrPDB 84 8e-17 2XRC-A nrPDB 83 8e-17 2B9L-A nrPDB 82 2e-16 4Z6A-H nrPDB 82 3e-16 2PKA-B nrPDB 81 4e-16 4IW4-E nrPDB 79 2e-15 4LK4-A nrPDB 79 3e-15 3VGC-B nrPDB 78 4e-15 2JET-B nrPDB 77 1e-14 3I77-A nrPDB 76 1e-14 5XRF-A nrPDB 75 2e-14 4KKD-A nrPDB 75 3e-14 3H7O-A nrPDB 72 3e-13 1ZJK-A nrPDB 72 3e-13 3NXP-A nrPDB 71 5e-13 1Q3X-A nrPDB 71 5e-13 3K65-B nrPDB 71 5e-13 1M9U-A nrPDB 70 7e-13 4NZQ-A nrPDB 70 8e-13 1PQ7-A nrPDB 70 9e-13 3BEU-A nrPDB 70 1e-12 1MKW-K nrPDB 69 2e-12 5UBM-A nrPDB 68 5e-12 1VR1-H nrPDB 67 6e-12 1ELV-A nrPDB 67 6e-12 6BQM-A nrPDB 67 7e-12 4FXG-H nrPDB 67 7e-12 2FMJ-A nrPDB 67 7e-12 1ETT-H nrPDB 67 7e-12 3H7T-A nrPDB 67 8e-12 2KAI-A nrPDB 67 1e-11 4J1Y-A nrPDB 65 2e-11 5TO3-B nrPDB 65 3e-11 2OCV-B nrPDB 64 6e-11 1YM0-A nrPDB 63 1e-10 4BXW-A nrPDB 63 1e-10 1EPT-B nrPDB 63 1e-10 4X0L-C nrPDB 62 3e-10 4WJG-C nrPDB 61 4e-10 1DLE-A nrPDB 58 5e-09 2WIN-I nrPDB 58 5e-09 2OK5-A nrPDB 57 7e-09 4F4O-C nrPDB 57 8e-09 1AKS-B nrPDB 56 1e-08 1BBR-H nrPDB 55 4e-08 1RIW-B nrPDB 51 5e-07 2I6S-A nrPDB 45 2e-05 3RU4-E nrPDB 44 9e-05 3F1S-B nrPDB 42 3e-04 3H5C-B nrPDB 42 4e-04 2JET-C nrPDB 37 0.006 2EA3-A nrPDB 33 0.16 2HNT-C nrPDB 31 0.41 5LAK-A nrPDB 30 1.1 3WSY-A nrPDB 29 2.0 1CDO-A nrPDB 28 5.3 >1IAU-A nrPDB Length = 227 Score = 479 bits (1234), Expect = e-136, Method: Compositional matrix adjust. Identities = 227/227 (100%), Positives = 227/227 (100%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 60 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 140 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ Sbjct: 61 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 120 Query: 141 TCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFK 200 TCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFK Sbjct: 121 TCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFK 180 Query: 201 GDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMKRY 247 GDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMKRY Sbjct: 181 GDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMKRY 227 >1FI8-A nrPDB Length = 228 Score = 337 bits (863), Expect = 3e-93, Method: Compositional matrix adjust. Identities = 159/227 (70%), Positives = 186/227 (81%), Gaps = 1/227 (0%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKS-LKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNI 79 IIGGHEAKPHSRPYMAYL I D+ S K+CGGFLIR+DFVLTAAHC GS I VTLGAHNI Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKIQVTLGAHNI 60 Query: 80 KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 KEQE QQ IPV + IPHPAYN K SNDIMLL+L+ KAKR+ AV+PL LP +VKPG Sbjct: 61 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 120 Query: 140 QTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 199 C VAGWG+ P+GK+S TLQEV++TVQED+KCES L++Y+D E+C GDP+IK+ SF Sbjct: 121 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF 180 Query: 200 KGDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMKR 246 +GDSGGPLVC KVA GIVSYG+N+G PRA TKVS+F+ WIKKTMK+ Sbjct: 181 RGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMKK 227 >3TK9-A nrPDB Length = 226 Score = 328 bits (841), Expect = 1e-90, Method: Compositional matrix adjust. Identities = 161/226 (71%), Positives = 180/226 (79%), Gaps = 1/226 (0%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 IIGGHEAKPHSRPYMA++ +KS KRCGG L+R DFVLTAAHC GSSINVTLGAHNIK Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQGSSINVTLGAHNIK 60 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 140 EQE TQQFIPVKRPIPHPAYNPKNFSN+IMLLQLERKAK T AV+PLRLPS+KAQVKPGQ Sbjct: 61 EQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQVKPGQ 120 Query: 141 TCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFK 200 CSVAGWG + + + TLQEV +TVQ+D +CE Y E+CVGDP+ +T FK Sbjct: 121 LCSVAGWGYVS-MSTLATTLQEVLLTVQKDCQCERLFHGNYSRATEICVGDPKKTQTGFK 179 Query: 201 GDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMKR 246 GDSGGPLVC VAQGI+SYG G PP KVS F+ WIK+TMKR Sbjct: 180 GDSGGPLVCKDVAQGILSYGNKKGTPPGVYIKVSHFLPWIKRTMKR 225 >1EUF-A nrPDB Length = 227 Score = 288 bits (737), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 138/227 (60%), Positives = 165/227 (72%), Gaps = 1/227 (0%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 IIGGHEAKPHSRPYMA+L+ CGGFL+R+DFVLTAAHC GSSINVTLGAHNI Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLGSSINVTLGAHNIM 60 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 140 E+E TQQ IPV+RPIPHP YN + +NDIMLL+L RKA T V P+ LP + A+VKPG Sbjct: 61 ERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAEVKPGM 120 Query: 141 TCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFK 200 CSVAGWG+ + LQEV + VQ + KC + ++Y T ++C GDP +K SF Sbjct: 121 MCSVAGWGRLGVNMPSTDKLQEVDLEVQSEEKCIARFKNYIPFT-QICAGDPSKRKNSFS 179 Query: 201 GDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMKRY 247 GDSGGPLVCN VAQGIVSYGRN+G P T++SSF+ WI TM+RY Sbjct: 180 GDSGGPLVCNGVAQGIVSYGRNDGTTPDVYTRISSFLSWIHSTMRRY 226 >3G01-A nrPDB Length = 227 Score = 286 bits (733), Expect = 5e-78, Method: Compositional matrix adjust. Identities = 141/228 (61%), Positives = 166/228 (72%), Gaps = 5/228 (2%) Query: 21 IIGGHEAKPHSRPYMAY---LMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAH 77 IIGG+E PHSRPYMAY L + +K CGGFL+RD FVLTAAHC G S+ VTLGAH Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMF--CGGFLVRDKFVLTAAHCKGRSMTVTLGAH 58 Query: 78 NIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVK 137 NIK +E TQQ IPV + IPHP YNP + SNDIMLL+L R AKRTRAV+PL LP A VK Sbjct: 59 NIKAKEETQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNAHVK 118 Query: 138 PGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKT 197 PG C VAGWG+ P G+ TL EVK+TVQ+D+ CES + Y+ E+CVGD +IK Sbjct: 119 PGDECYVAGWGKVTPDGEFPKTLHEVKLTVQKDQVCESQFQSSYNRANEICVGDSKIKGA 178 Query: 198 SFKGDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMK 245 SF+GDSGGPLVC + A GIVSYG+ +G P+ T+V SFV WIKKTMK Sbjct: 179 SFRGDSGGPLVCKRAAAGIVSYGQTDGSAPQVFTRVLSFVSWIKKTMK 226 >1KYN-A nrPDB Length = 235 Score = 258 bits (658), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 128/229 (55%), Positives = 168/229 (73%), Gaps = 6/229 (2%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 IIGG E++PHSRPYMAYL I RCGGFL+R+DFVLTAAHCWGS+INVTLGAHNI+ Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQ 60 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 140 +E TQQ I +R I HP YN + NDIMLLQL R+ +R R V P+ LP + ++PG Sbjct: 61 RRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGT 120 Query: 141 TCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHY--YDSTIELCVGDPEIKKTS 198 C+VAGWG+ + + + + TL+EV++ VQ DR+C LR + YD ++CVGD +K + Sbjct: 121 LCTVAGWGRVS-MRRGTDTLREVQLRVQRDRQC---LRIFGSYDPRRQICVGDRRERKAA 176 Query: 199 FKGDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMKRY 247 FKGDSGGPL+CN VA GIVSYG+++G+PP T+VSSF+ WI+ TM+ + Sbjct: 177 FKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSF 225 >1NN6-A nrPDB Length = 228 Score = 232 bits (591), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 122/228 (53%), Positives = 152/228 (66%), Gaps = 3/228 (1%) Query: 19 GEIIGGHEAKPHSRPYMAYL-MIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAH 77 GEIIGG E KPHSRPYMAYL ++ K CGGFLIR +FVLTAAHC G SI VTLGAH Sbjct: 1 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAH 60 Query: 78 NIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVK 137 NI E+E T Q + V + HP YN +DIMLL+L+ KA T AV L PS V Sbjct: 61 NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVP 120 Query: 138 PGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKT 197 PG+ C VAGWG+T L S TLQEVK+ + + + C S R +D ++LCVG+P K+ Sbjct: 121 PGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQAC-SHFRD-FDHNLQLCVGNPRKTKS 178 Query: 198 SFKGDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMK 245 +FKGDSGGPL+C VAQGIVSYGR++ PP T++S + WI + ++ Sbjct: 179 AFKGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQ 226 >3RP2-A nrPDB Length = 224 Score = 209 bits (531), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 109/225 (48%), Positives = 147/225 (65%), Gaps = 3/225 (1%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKR-CGGFLIRDDFVLTAAHCWGSSINVTLGAHNI 79 IIGG E+ PHSRPYMA+L I +K L+ CGGFLI FVLTAAHC G I V LGAH++ Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCKGREITVILGAHDV 60 Query: 80 KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 +++E TQQ I V++ I H +YN +DIMLL+LE+K + T AV + LPS + PG Sbjct: 61 RKRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDFIHPG 120 Query: 140 QTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 199 C AGWG+T S+TL+EV++ + +++ C D R YY+ ++CVG P + +F Sbjct: 121 AMCWAAGWGKTGVRDPTSYTLREVELRIMDEKAC-VDYR-YYEYKFQVCVGSPTTLRAAF 178 Query: 200 KGDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTM 244 GDSGGPL+C VA GIVSYG + PP T+VS++V WI + Sbjct: 179 MGDSGGPLLCAGVAHGIVSYGHPDAKPPAIFTRVSTYVPWINAVI 223 >2RDL-A nrPDB Length = 226 Score = 199 bits (507), Expect = 7e-52, Method: Compositional matrix adjust. Identities = 105/228 (46%), Positives = 141/228 (61%), Gaps = 7/228 (3%) Query: 21 IIGGHEAKPHSRPYMAYL-MIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNI 79 IIGG E +PH+RPYMAYL ++ + L C GFLIR +FV+TAAHC G SI V LGAHN Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAGRSITVLLGAHNK 60 Query: 80 KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 K +E T Q + V++ PHP Y+ + NDIMLL+L+ KA T V L + + + PG Sbjct: 61 KVKEDTWQKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPISAKSNSIPPG 120 Query: 140 QTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIE--LCVGDPEIKKT 197 + C GWG+T S TLQEVKM + + + C +H+ D E LCVG+P+ + Sbjct: 121 RVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQAC----KHFEDFHQEPQLCVGNPKKIRN 176 Query: 198 SFKGDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMK 245 +KGDSGGPL+C +AQGI SY N PP T++S + WI K ++ Sbjct: 177 VYKGDSGGPLLCAGIAQGIASYVLRNAKPPSVFTRISHYRPWINKILR 224 >1ORF-A nrPDB Length = 234 Score = 163 bits (413), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 94/208 (45%), Positives = 123/208 (59%), Gaps = 9/208 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-WGSSINVTLGAHNI 79 IIGG+E PHSRPYM L + D+K++ C G LI D+VLTAAHC V LGAH+I Sbjct: 1 IIGGNEVTPHSRPYMVLLSL-DRKTI--CAGALIAKDWVLTAAHCNLNKRSQVILGAHSI 57 Query: 80 KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 +EPT+Q + VK+ P+P Y+P D+ LLQL KAK + V L LP VKPG Sbjct: 58 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDVKPG 117 Query: 140 QTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHY-YDSTIEL---CVGDPEIK 195 C VAGWG+T S TL+EV++T+ DRK +D HY ++ I + C G Sbjct: 118 TMCQVAGWGRTHNSASWSDTLREVEITII-DRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 176 Query: 196 KTSFKGDSGGPLVCNKVAQGIVSYGRNN 223 + S GDSG PL+C V +G+ S+G N Sbjct: 177 RDSCNGDSGSPLLCEGVFRGVTSFGLEN 204 >1UTJ-A nrPDB Length = 242 Score = 162 bits (409), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 93/249 (37%), Positives = 134/249 (53%), Gaps = 13/249 (5%) Query: 5 LLLLAFLLLPRA----DAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVL 60 ++ L F+LL A + +I+GG+E KP+S+P+ L CGG L+ +++V+ Sbjct: 1 MISLVFVLLIGAAFATEDDKIVGGYECKPYSQPHQVSL----NSGYHFCGGSLVNENWVV 56 Query: 61 TAAHCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKR 120 +AAHC+ S + V LG HNIK E ++QFI R I HP Y+ N NDIML++L + A Sbjct: 57 SAAHCYKSRVEVRLGEHNIKVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPATL 116 Query: 121 TRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHY 180 VQP+ LP++ A G C+V+GWG T S+ LQ + + + C + Sbjct: 117 NTYVQPVALPTSCA--PAGTMCTVSGWGNTMSSTADSNKLQCLNIPILSYSDCNNSYPGM 174 Query: 181 YDSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNNGMP--PRACTKVSSFVH 238 + + C G E K S +GDSGGP+VCN QG+VS+G P P KV F Sbjct: 175 ITNAM-FCAGYLEGGKDSCQGDSGGPVVCNGELQGVVSWGYGCAEPGNPGVYAKVCIFND 233 Query: 239 WIKKTMKRY 247 W+ TM Y Sbjct: 234 WLTSTMASY 242 >1FDP-A nrPDB Length = 235 Score = 151 bits (381), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 87/234 (37%), Positives = 125/234 (53%), Gaps = 13/234 (5%) Query: 19 GEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSS----INVTL 74 G I+GG EA+ H+RPYMA + + CGG L+ + +VL+AAHC + + V L Sbjct: 6 GRILGGREAEAHARPYMASVQL---NGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLL 62 Query: 75 GAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKA 134 GAH++ + EP+++ V R +PHP P +D++LLQL KA AV+PL Sbjct: 63 GAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDR 122 Query: 135 QVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTI-ELCVGDPE 193 V PG C VAGWG G+ +LQ V + V + C R ++D I E + Sbjct: 123 DVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNR--RTHHDGAITERLMCAES 180 Query: 194 IKKTSFKGDSGGPLVCNKVAQGIVSYGR---NNGMPPRACTKVSSFVHWIKKTM 244 ++ S KGDSGGPLVC V +G+V+ G N P T+V+S+ WI + Sbjct: 181 NRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVL 234 >5FXL-A nrPDB Length = 246 Score = 149 bits (377), Expect = 8e-37, Method: Compositional matrix adjust. Identities = 89/244 (36%), Positives = 126/244 (51%), Gaps = 10/244 (4%) Query: 4 ILLLLAFLLLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAA 63 + LL A + P D +I+GG+ ++ PY L CGG LI +V++AA Sbjct: 7 LALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSL----NSGYHFCGGSLINSQWVVSAA 62 Query: 64 HCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRA 123 HC+ S I V LG NI E +QFI + I HP+YN +NDIML++L+ A Sbjct: 63 HCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSR 122 Query: 124 VQPLRLPSNKAQVKPGQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYD 182 V + LP++ A G C ++GWG T G + L+ +K + D C+S Sbjct: 123 VASISLPTSCASA--GTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQIT 180 Query: 183 STIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNNGM--PPRACTKVSSFVHWI 240 S + C G E K S +GDSGGP+VC+ QGIVS+G P TKV ++V WI Sbjct: 181 SNM-FCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWI 239 Query: 241 KKTM 244 K+T+ Sbjct: 240 KQTI 243 >5FCR-A nrPDB Length = 234 Score = 149 bits (375), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 79/231 (34%), Positives = 127/231 (54%), Gaps = 14/231 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG-----SSINVTLG 75 I+GG EA H+RPYMA + + CGG L+ + +VL+AAHC S+ V LG Sbjct: 1 ILGGQEAAAHARPYMASVQV---NGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLG 57 Query: 76 AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ 135 AH++ EP +++ V+ +PHP P + +D++L +L + A V+PL L + Sbjct: 58 AHSLSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDKE 117 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEI- 194 V+PG C VAGWG G+ L ++++++ C +LR Y+D + + + E Sbjct: 118 VEPGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTC--NLRTYHDGVVTINMMCAESN 175 Query: 195 KKTSFKGDSGGPLVCNKVAQGIVSYGR---NNGMPPRACTKVSSFVHWIKK 242 ++ + +GDSG PLVC +G+V++G NG P T+VSS+ WI+ Sbjct: 176 RRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIEN 226 >1FUJ-A nrPDB Length = 221 Score = 148 bits (374), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 88/232 (37%), Positives = 122/232 (52%), Gaps = 18/232 (7%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSS----INVTLGA 76 I+GGHEA+PHSRPYMA L + CGG LI FVLTAAHC +NV LGA Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 60 Query: 77 HNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQV 136 HN++ QEPTQQ V + + Y+ +N NDI+L+QL A + +V ++LP V Sbjct: 61 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDILLIQLSSPANLSASVATVQLPQQDQPV 119 Query: 137 KPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKK 196 G C GWG+ + LQE+ +TV ++ +C P K Sbjct: 120 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT----------FFCRPHNICTFVPRRKA 169 Query: 197 TSFKGDSGGPLVCNKVAQGIVSY---GRNNGMPPRACTKVSSFVHWIKKTMK 245 GDSGGPL+C+ + QGI S+ G + P T+V+ +V WI+ T++ Sbjct: 170 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 221 >1A0J-A nrPDB Length = 223 Score = 147 bits (372), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 90/231 (38%), Positives = 121/231 (52%), Gaps = 16/231 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 I+GG+E + +S Y A L Q CGG LI +V++AAHC+ S I V LG HNI Sbjct: 1 IVGGYECRKNSASYQASL----QSGYHFCGGSLISSTWVVSAAHCYKSRIQVRLGEHNIA 56 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 140 E T+QFI + I HP+YN +N NDIML++L + A V + LPS+ A G Sbjct: 57 VNEGTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALPSSCA--SSGT 114 Query: 141 TCSVAGWGQ-TAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 199 C V+GWG + + TL+ + + + C S S + C G E K S Sbjct: 115 RCLVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQITSNM-FCAGFMEGGKDSC 173 Query: 200 KGDSGGPLVCNKVAQGIVSYG-----RNNGMPPRACTKVSSFVHWIKKTMK 245 +GDSGGP+VCN QG+VS+G RN P TKV ++ WI TM Sbjct: 174 QGDSGGPVVCNGQLQGVVSWGYGCAQRN---KPGVYTKVCNYRSWISSTMS 221 >4AN7-A nrPDB Length = 231 Score = 146 bits (368), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 89/235 (37%), Positives = 120/235 (51%), Gaps = 10/235 (4%) Query: 13 LPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINV 72 P D +I+GG+ +S PY L CGG LI +V++AAHC+ S I V Sbjct: 1 FPTDDDDKIVGGYTCAANSIPYQVSL----NSGSHFCGGSLINSQWVVSAAHCYKSRIQV 56 Query: 73 TLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSN 132 LG HNI E +QFI + I HP +N NDIML++L A V + LP Sbjct: 57 RLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLP-- 114 Query: 133 KAQVKPGQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGD 191 ++ G C ++GWG T G + LQ +K V D C+S + +CVG Sbjct: 115 RSCAAAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNM-ICVGF 173 Query: 192 PEIKKTSFKGDSGGPLVCNKVAQGIVS--YGRNNGMPPRACTKVSSFVHWIKKTM 244 E K S +GDSGGP+VCN QGIVS YG P TKV ++V+WI++T+ Sbjct: 174 LEGGKDSCQGDSGGPVVCNGQLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQTI 228 >4Q7Y-A nrPDB Length = 250 Score = 145 bits (366), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 95/235 (40%), Positives = 124/235 (52%), Gaps = 13/235 (5%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG----SSINVTLGA 76 IIGGHE PHSRPYMA + Q CGGFL+R +V++AAHC+ + V LGA Sbjct: 1 IIGGHEVTPHSRPYMASVRFGGQH---HCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGA 57 Query: 77 HNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ- 135 H + EPTQQ + HP Y+P +NDI LL+L A AV LRLP +A+ Sbjct: 58 HVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRARP 117 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIK 195 G C VAGWG + + L E K+ V + C S + + T+ LC + Sbjct: 118 PTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTM-LCTRSGDSH 176 Query: 196 KTSF-KGDSGGPLVCNKVAQGIVSY-GRNNGMP--PRACTKVSSFVHWIKKTMKR 246 + F DSGGPLVC A G+VS+ G G P P T+VS+FV WI ++R Sbjct: 177 RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 231 >1F7Z-A nrPDB Length = 233 Score = 145 bits (365), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 88/235 (37%), Positives = 122/235 (51%), Gaps = 10/235 (4%) Query: 13 LPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINV 72 P D I+GG+ + +S PY L CGG LI D +V++AAHC+ S I V Sbjct: 3 FPVDDDDAIVGGYTCQENSVPYQVSL----NSGYHFCGGSLINDQWVVSAAHCYKSRIQV 58 Query: 73 TLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSN 132 LG HNI E +QF+ + I HP ++ K +NDIML++L K V + LPS+ Sbjct: 59 RLGEHNINVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVALPSS 118 Query: 133 KAQVKPGQTCSVAGWGQTAPLGKHS-HTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGD 191 A G C ++GWG T G + LQ + + CE+ + +CVG Sbjct: 119 CA--PAGTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKITDNM-VCVGF 175 Query: 192 PEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNNGMP--PRACTKVSSFVHWIKKTM 244 E K S +GDSGGP+VCN QGIVS+G +P P TKV ++V WI+ T+ Sbjct: 176 LEGGKDSCQGDSGGPVVCNGELQGIVSWGYGCALPDNPGVYTKVCNYVDWIQDTI 230 >2ZKS-A nrPDB Length = 240 Score = 142 bits (357), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 89/238 (37%), Positives = 125/238 (52%), Gaps = 20/238 (8%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG---SSINVTLGAH 77 IIGG E PHSRPYMA L + CGG L+ +VLTAAHC + + + LG H Sbjct: 1 IIGGREVIPHSRPYMASL---QRNGSHLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLGLH 57 Query: 78 NIKEQEPTQQFIPVKRPIPHPAYNP-KNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQV 136 + P F +K I HP Y P ND+ LLQL+ K K +R ++PL LPS + V Sbjct: 58 TL--DSPGLTF-HIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQVV 114 Query: 137 KPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIE---LCVGDPE 193 G CS+AGWG T G+ S L+E+ + V + R C + +++ ++ +C+ Sbjct: 115 AAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNS--RFWNGSLSPSMVCLAADS 172 Query: 194 IKKTSFKGDSGGPLVCNK--VAQGIVSYGR---NNGMPPRACTKVSSFVHWIKKTMKR 246 + KGDSGGPLVC K V G++S+ + P T V+ +V WI+K R Sbjct: 173 KDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKVTGR 230 >1MZD-A nrPDB Length = 240 Score = 140 bits (354), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 92/237 (38%), Positives = 124/237 (52%), Gaps = 16/237 (6%) Query: 20 EIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW-----GSSINVTL 74 EIIGG E PHSRP+MA + CGG LI +VLTAAHC G S V L Sbjct: 2 EIIGGKEVSPHSRPFMASIQYGGHHV---CGGVLIDPQWVLTAAHCQYRFTKGQSPTVVL 58 Query: 75 GAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKA 134 GAH++ + E ++Q + +K+ IP SNDIML++L+ AK + V+ L + S K Sbjct: 59 GAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRS-KT 117 Query: 135 QVKPGQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIE---LCVG 190 ++ G C V GWG T P + S TL+EV +TV + C S + D I +C G Sbjct: 118 SLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAG 177 Query: 191 DPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNNGM---PPRACTKVSSFVHWIKKTM 244 D + +K S KGD+GGPL+C V IVS G G+ P + WIK + Sbjct: 178 DAKGQKDSCKGDAGGPLICKGVFHAIVSGGHECGVATKPGIYTLLTKKYQTWIKSNL 234 >4WWY-A nrPDB Length = 224 Score = 140 bits (353), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 87/227 (38%), Positives = 119/227 (52%), Gaps = 10/227 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 I+GG+ + +S PY L CGG LI + +V++A HC+ S I V LG HNI+ Sbjct: 1 IVGGYNCEENSVPYQVSL----NSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIE 56 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 140 E +QFI + I HP Y+ K +NDIML++L +A V + LP+ A G Sbjct: 57 VLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLPT--APPATGT 114 Query: 141 TCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 199 C ++GWG TA G + LQ + V KCE+ S + CVG E K S Sbjct: 115 KCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNM-FCVGFLEGGKDSC 173 Query: 200 KGDSGGPLVCNKVAQGIVSYGRNNGM--PPRACTKVSSFVHWIKKTM 244 + DSGGP+VCN QG+VS+G P TKV ++V WIK T+ Sbjct: 174 QRDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTI 220 >5MS3-A nrPDB Length = 228 Score = 140 bits (353), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 85/231 (36%), Positives = 125/231 (54%), Gaps = 14/231 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 ++GGHE +PHS+P+ A L Q CGG L+ ++VLTAAHC V LG H+++ Sbjct: 1 VLGGHECQPHSQPWQAALF---QGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 57 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSN---DIMLLQLERKAKRTRAVQPLRLPSNKAQVK 137 ++ +Q IPV + IPHP YN + + D+MLLQL +A V+P+ L + Q Sbjct: 58 NKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQ-- 115 Query: 138 PGQTCSVAGWGQ-TAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKK 196 PGQ C+V+GWG T+P TL ++ + +KCE + +C G + Sbjct: 116 PGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGM-VCAGSSKGAD 174 Query: 197 TSFKGDSGGPLVCNKVAQGIVSYGRN---NGMPPRACTKVSSFVHWIKKTM 244 T +GDSGGPLVC+ QGI S+G + P T + ++ WIKK + Sbjct: 175 TC-QGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 224 >1SGF-G nrPDB Length = 237 Score = 137 bits (345), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 84/242 (34%), Positives = 133/242 (54%), Gaps = 23/242 (9%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 I+GG + + +S+P+ + + Q CGG L+ ++VLTAAHC+ + V LG +N+ Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQY---LCGGVLLDPNWVLTAAHCYDDNYKVWLGKNNLF 57 Query: 81 EQEPTQQFIPVKRPIPHPAYN-----------PKNFSNDIMLLQLERKAKRTRAVQPLRL 129 + EP+ Q V + IPHP +N ++SND+MLL+L + A T V+P+ L Sbjct: 58 KDEPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPITL 117 Query: 130 PSNKAQVKPGQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKC-ESDLRHYYDSTIEL 187 P+ + ++ G TC +GWG P + + L V + + + C ++ + D+ L Sbjct: 118 PTEEPKL--GSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIEKVTDAM--L 173 Query: 188 CVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRN-NGMP--PRACTKVSSFVHWIKKTM 244 C G+ + K + KGDSGGPL+C+ V QGI S+G G P P TK++ F WIK TM Sbjct: 174 CAGEMDGGKDTCKGDSGGPLICDGVLQGITSWGHTPCGEPDMPGVYTKLNKFTSWIKDTM 233 Query: 245 KR 246 + Sbjct: 234 AK 235 >1NPM-A nrPDB Length = 225 Score = 135 bits (341), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 90/233 (38%), Positives = 129/233 (55%), Gaps = 18/233 (7%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 I+ G E PHS+P+ A L Q CGG L+ D +VLTAAHC +V LG H+++ Sbjct: 1 ILEGRECIPHSQPWQAALF---QGERLICGGVLVGDRWVLTAAHCKKQKYSVRLGDHSLQ 57 Query: 81 EQEPTQQFIPVKRPIPHPAY---NPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVK 137 ++ +Q I V + I HP Y NP++ S+DIML++L+ A V+P++L + +V Sbjct: 58 SRDQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQLANLCPKV- 116 Query: 138 PGQTCSVAGWGQ-TAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIE--LCVGDPEI 194 GQ C ++GWG T+P +TL ++ + KCE R Y E +C G Sbjct: 117 -GQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCE---RAYPGKITEGMVCAGSSNG 172 Query: 195 KKTSFKGDSGGPLVCNKVAQGIVSYGRN-NGMP--PRACTKVSSFVHWIKKTM 244 T +GDSGGPLVC+ + QGI S+G + G P P TK+ + WIKKTM Sbjct: 173 ADTC-QGDSGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTM 224 >2TLD-E nrPDB Length = 220 Score = 135 bits (340), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 82/226 (36%), Positives = 116/226 (51%), Gaps = 11/226 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 I+GG+ ++ PY L CGG LI +V++AAHC+ S I V LG NI Sbjct: 1 IVGGYTCGANTVPYQVSL----NSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNIN 56 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 140 E +QFI + I HP+YN +NDIML++L+ A V + LP++ A G Sbjct: 57 VVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASA--GT 114 Query: 141 TCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 199 C ++GWG T G + L+ +K + D C+S S + C G S Sbjct: 115 QCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNM-FCAGLE--GGDSC 171 Query: 200 KGDSGGPLVCNKVAQGIVSYGRNNGM-PPRACTKVSSFVHWIKKTM 244 +GDSGGP+VC+ QGIVS+G P TKV ++V WIK+T+ Sbjct: 172 QGDSGGPVVCSGKLQGIVSWGSGCAKNKPGVYTKVCNYVSWIKQTI 217 >1SPJ-A nrPDB Length = 238 Score = 135 bits (340), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 88/243 (36%), Positives = 127/243 (52%), Gaps = 24/243 (9%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 I+GG E + HS+P+ A L S +CGG L+ +VLTAAHC + + LG HN+ Sbjct: 1 IVGGWECEQHSQPWQAALY---HFSTFQCGGILVHRQWVLTAAHCISDNYQLWLGRHNLF 57 Query: 81 EQEPTQQFIPVKRPIPHPAYN-----------PKNFSNDIMLLQLERKAKR-TRAVQPLR 128 + E T QF+ V PHP +N +++S+D+MLL+L A T AV+ + Sbjct: 58 DDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVE 117 Query: 129 LPSNKAQVKPGQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDST-IE 186 LP+ + +V G TC +GWG P LQ V + + + +C+ H T Sbjct: 118 LPTEEPEV--GSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKK--AHVQKVTDFM 173 Query: 187 LCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRN-NGMP--PRACTKVSSFVHWIKKT 243 LCVG E K + GDSGGPL+C+ V QG+ S+G G P P +V S+V WI+ T Sbjct: 174 LCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDT 233 Query: 244 MKR 246 + Sbjct: 234 IAE 236 >2EEK-A nrPDB Length = 220 Score = 134 bits (338), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 78/226 (34%), Positives = 114/226 (50%), Gaps = 9/226 (3%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 I+GG+E HS+ + L CGG L+ D+V++AAHC+ S + V LG H+I+ Sbjct: 1 IVGGYECTKHSQAHQVSL----NSGYHFCGGSLVSKDWVVSAAHCYKSVLRVRLGEHHIR 56 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 140 E T+Q+I I HP Y+ N +NDIML++L + A + V + LP+ A Sbjct: 57 VNEGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPTECA--ADAT 114 Query: 141 TCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFK 200 C+V+GWG T LQ + + + C + ++ C G E K S + Sbjct: 115 MCTVSGWGNTMSSVADGDKLQCLSLPILSHADCANSYPGMITQSM-FCAGYLEGGKDSCQ 173 Query: 201 GDSGGPLVCNKVAQGIVSYGRNNGM--PPRACTKVSSFVHWIKKTM 244 GDSGGP+VCN V QG+VS+G P KV W++ TM Sbjct: 174 GDSGGPVVCNGVLQGVVSWGYGCAERDHPGVYAKVCVLSGWVRDTM 219 >5C67-A nrPDB Length = 224 Score = 132 bits (331), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 82/227 (36%), Positives = 117/227 (51%), Gaps = 10/227 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 I+GG+ + +S PY L CGG LI + +V++AAHC+ + I V LG HNIK Sbjct: 1 IVGGYTCEENSLPYQVSL----NSGSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIK 56 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 140 E +QFI + I HP YN NDIML++L A V + LP+ A G Sbjct: 57 VLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPT--APPAAGT 114 Query: 141 TCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 199 C ++GWG T G + L+ + V +C++ +++ CVG E K S Sbjct: 115 ECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSM-FCVGFLEGGKDSC 173 Query: 200 KGDSGGPLVCNKVAQGIVSYGRNNGMP--PRACTKVSSFVHWIKKTM 244 + D+GGP+VCN QG+VS+G P TKV ++V WIK T+ Sbjct: 174 QRDAGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTI 220 >4NFE-A nrPDB Length = 237 Score = 130 bits (328), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 90/241 (37%), Positives = 120/241 (49%), Gaps = 25/241 (10%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 I+GG E + HS+P+ + CGG L+ +VLTAAHC + V LG HN+ Sbjct: 1 IVGGWECEKHSQPWQVAVY---SHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 57 Query: 81 EQEPTQQFIPVKRPIPHPAYN-----------PKNFSNDIMLLQLERKAKRTRAVQPLRL 129 E E T Q +PV PHP YN ++ S+D+MLL+L AK T V+ L L Sbjct: 58 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 117 Query: 130 PSNKAQVKPGQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIE-- 186 P+ + + G TC +GWG P +LQ V + + + C R Y + E Sbjct: 118 PTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCA---RAYSEKVTEFM 172 Query: 187 LCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYG-RNNGMP--PRACTKVSSFVHWIKKT 243 LC G K + GDSGGPLVCN V QGI S+G +P P TKV + WIK T Sbjct: 173 LCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDT 232 Query: 244 M 244 + Sbjct: 233 I 233 >1TON-A nrPDB Length = 235 Score = 130 bits (328), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 86/243 (35%), Positives = 126/243 (51%), Gaps = 27/243 (11%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 I+GG++ + +S+P+ ++ + CGG LI +V+TAAHC+ ++ V LG +N+ Sbjct: 1 IVGGYKCEKNSQPWQVAVI-----NEYLCGGVLIDPSWVITAAHCYSNNYQVLLGRNNLF 55 Query: 81 EQEPTQQFIPVKRPIPHPAYNP-----------KNFSNDIMLLQLERKAKRTRAVQPLRL 129 + EP Q V++ HP Y P + SND+MLL L A T V+ + L Sbjct: 56 KDEPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVIDL 115 Query: 130 PSNKAQVKPGQTCSVAGWGQTAPLGK-HSHTLQEVKMTVQEDRKCESDLRHYYDSTIE-- 186 P+ + +V G TC +GWG T P SH LQ V + + + KC + Y D+ + Sbjct: 116 PTKEPKV--GSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKC---IETYKDNVTDVM 170 Query: 187 LCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNNGMPPRA---CTKVSSFVHWIKKT 243 LC G+ E K + GDSGGPL+C+ V QGI S G P+ K+ F WIKK Sbjct: 171 LCAGEMEGGKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKV 230 Query: 244 MKR 246 MK Sbjct: 231 MKE 233 >1SGF-A nrPDB Length = 240 Score = 130 bits (326), Expect = 7e-31, Method: Compositional matrix adjust. Identities = 79/213 (37%), Positives = 116/213 (54%), Gaps = 20/213 (9%) Query: 48 RCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYN------ 101 +CGG L+ ++VLTAAHC+ V LG +N E EP+ Q V + IPHP +N Sbjct: 28 QCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNE 87 Query: 102 -----PKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLG-K 155 ++SND+MLL+L + A T V+P+ LP+ + ++ G TC +GWG T P+ K Sbjct: 88 HTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKL--GSTCLASGWGSTTPIKFK 145 Query: 156 HSHTLQEVKMTVQEDRKCESDLRHYYDST-IELCVGDPEIKKTSFKGDSGGPLVCNKVAQ 214 + LQ V + + + C D H T LC G+ + + + DSGGPL+C+ + Q Sbjct: 146 YPDDLQCVNLKLLPNEDC--DKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDGILQ 203 Query: 215 GIVSYG-RNNGMP--PRACTKVSSFVHWIKKTM 244 GI S+G G P P TK+ F WI++TM Sbjct: 204 GITSWGPEPCGEPTEPSVYTKLIKFSSWIRETM 236 >5ZFH-A nrPDB Length = 224 Score = 126 bits (317), Expect = 8e-30, Method: Compositional matrix adjust. Identities = 82/231 (35%), Positives = 121/231 (52%), Gaps = 12/231 (5%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 II G++ K S P+ L+ +Q CGG L+ +VLTAAHC V LG+ I Sbjct: 1 IIDGYKCKEGSHPWQVALLKGNQL---HCGGVLVDKYWVLTAAHCKMGQYQVQLGSDKIG 57 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 140 +Q + Q I + HP Y+ K NDIML++L+ K + V+ ++LP + PG Sbjct: 58 DQ--SAQKIKATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLPEHCE--PPGT 113 Query: 141 TCSVAGWGQT-APLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 199 +C+V+GWG T +P L + + R+C+ + T+ LC G P+ K + Sbjct: 114 SCTVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKVYKDLLGKTM-LCAGIPDSKTNTC 172 Query: 200 KGDSGGPLVCNKVAQGIVSYGRN-NGMP--PRACTKVSSFVHWIKKTMKRY 247 GDSGGPLVCN QG+VS+G G P P T+V + W+ +TMK + Sbjct: 173 NGDSGGPLVCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETMKTH 223 >2BDH-A nrPDB Length = 223 Score = 125 bits (315), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 75/229 (32%), Positives = 122/229 (53%), Gaps = 11/229 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 II G + PHS+P+ A L++ ++ C G L+ +VL+AAHC+ +S + LG H+++ Sbjct: 1 IINGEDCSPHSQPWQAALVMENEL---FCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLE 57 Query: 81 -EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 +QEP Q + + HP YN +ND+ML++L+ + ++ + + S G Sbjct: 58 ADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTA--G 115 Query: 140 QTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 199 +C V+GWG A G+ LQ V ++V + C Y ++ C G + +K S Sbjct: 116 NSCLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSM-FCAGGGQDQKDSC 173 Query: 200 KGDSGGPLVCNKVAQGIVSYGR---NNGMPPRACTKVSSFVHWIKKTMK 245 GDSGGPL+CN QG+VS+G+ P T + F WI+KT++ Sbjct: 174 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 222 >1AO5-A nrPDB Length = 237 Score = 124 bits (310), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 80/241 (33%), Positives = 124/241 (51%), Gaps = 21/241 (8%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 ++GG + +S+P+ + ++ QK CGG L+ ++VLTAAHC+ V LG + + Sbjct: 1 VVGGFNCEKNSQPWQ--VAVYYQKE-HICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLF 57 Query: 81 EQEPTQQFIPVKRPIPHPAYN-----------PKNFSNDIMLLQLERKAKRTRAVQPLRL 129 ++EP+ Q V + PHP +N +FS+D+MLL+L + A T V+P+ L Sbjct: 58 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPIAL 117 Query: 130 PSNKAQVKPGQTCSVAGWGQTAPL-GKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELC 188 P+ + KPG C +GWG P + LQ V +T+ + C + + LC Sbjct: 118 PTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKV-TDVMLC 174 Query: 189 VGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYG-RNNGMP--PRACTKVSSFVHWIKKTMK 245 G+ K + + DSGGPL+C+ + QG SYG G P P T + F WIK TM Sbjct: 175 AGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMM 234 Query: 246 R 246 + Sbjct: 235 K 235 >3BSQ-A nrPDB Length = 227 Score = 124 bits (310), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 81/229 (35%), Positives = 119/229 (51%), Gaps = 12/229 (5%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 II G S P+ L+ +Q CGG L+ + +VLTAAHC + V LG+ + Sbjct: 1 IIDGAPCARGSHPWQVALLSGNQL---HCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG 57 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 140 ++ Q I + HP Y+ + ND+ML++L +A+ + V+ +RLPS PG Sbjct: 58 DRR--AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPGT 113 Query: 141 TCSVAGWGQT-APLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 199 TC+V+GWG T +P L V + + + C + ++++ LC G P+ KK + Sbjct: 114 TCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSM-LCAGIPDSKKNAC 172 Query: 200 KGDSGGPLVCNKVAQGIVSYGR-NNGMP--PRACTKVSSFVHWIKKTMK 245 GDSGGPLVC QG+VS+G G P P T+V F WI TMK Sbjct: 173 NGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 221 >2PSX-A nrPDB Length = 227 Score = 122 bits (307), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 79/232 (34%), Positives = 124/232 (53%), Gaps = 15/232 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 II G + H++P+ A L++ + + CG L+ ++LTAAHC V LG +++ Sbjct: 1 IINGSDCDMHTQPWQAALLL--RPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 58 Query: 81 E-QEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 E QQ + IPHP Y+ SND+ML++L R+ + T+ V+P+ + S+ G Sbjct: 59 PVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSA--G 116 Query: 140 QTCSVAGWGQT-APLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTS 198 C V+GWG T +P LQ + ++V ++CE D T+ C GD + + S Sbjct: 117 TKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTM-FCAGD-KAGRDS 174 Query: 199 FKGDSGGPLVCNKVAQGIVSYG-----RNNGMPPRACTKVSSFVHWIKKTMK 245 +GDSGGP+VCN QG+VS+G R N P T + F WI++T++ Sbjct: 175 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNR--PGVYTNLCKFTKWIQETIQ 224 >1AZZ-A nrPDB Length = 226 Score = 122 bits (306), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 84/229 (36%), Positives = 117/229 (51%), Gaps = 16/229 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSS--INVTLGAHN 78 I+GG EA P+S P+ A L I D + CGG LI +++LTAAHC + ++V LGAHN Sbjct: 1 IVGGVEAVPNSWPHQAALFIDD---MYFCGGSLISPEWILTAAHCMDGAGFVDVVLGAHN 57 Query: 79 IKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKP 138 I+E E TQ I H YN SNDI +++L T A+ + LPS V Sbjct: 58 IREDEATQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPSTDVGV-- 115 Query: 139 GQTCSVAGWG--QTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKK 196 G + GWG + LG S L++V + + + C++ D I C+ D K Sbjct: 116 GTVVTPTGWGLPSDSALGI-SDVLRQVDVPIMSNADCDAVYGIVTDGNI--CI-DSTGGK 171 Query: 197 TSFKGDSGGPLVCNKVAQGIVSYGRNNGMP---PRACTKVSSFVHWIKK 242 + GDSGGPL N + GI S+G G P A T+V+ F+ WI+ Sbjct: 172 GTCNGDSGGPLNYNGLTYGITSFGAAAGCEAGYPDAFTRVTYFLDWIQT 220 >4DGJ-A nrPDB Length = 235 Score = 121 bits (303), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 74/238 (31%), Positives = 120/238 (50%), Gaps = 18/238 (7%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-WGSSI-----NVTL 74 I+GG +AK + P++ L +D + L CG L+ D++++AAHC +G ++ L Sbjct: 1 IVGGSDAKEGAWPWVVGLY-YDDRLL--CGASLVSSDWLVSAAHCVYGRNLEPSKWTAIL 57 Query: 75 GAHNIKEQEPTQQFIP--VKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSN 132 G H +K + Q +P + + +P YN + NDI ++ LE K T +QP+ LP Sbjct: 58 GLH-MKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPEE 116 Query: 133 KAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDP 192 PG+ CS+AGWG G + LQE + + + +C+ + Y + +C G Sbjct: 117 NQVFPPGRNCSIAGWGTVVYQGTTADILQEADVPLLSNERCQQQMPEYNITENMICAGYE 176 Query: 193 EIKKTSFKGDSGGPLVCNK----VAQGIVSYGRNNGMP--PRACTKVSSFVHWIKKTM 244 E S +GDSGGPL+C + G+ S+G +P P +VS F WI+ + Sbjct: 177 EGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYECALPNRPGVYARVSRFTEWIQSFL 234 >6QHB-A nrPDB Length = 223 Score = 120 bits (300), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 85/222 (38%), Positives = 117/222 (52%), Gaps = 18/222 (8%) Query: 31 SRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIKEQEPTQQFIP 90 S PY A L CGG LI +VLTAAHC ++ V LG HN+ +QE +Q+ Sbjct: 11 SHPYQAALYT---SGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLGQQESSQEQSS 67 Query: 91 VKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSN-KAQVKPGQTCSVAGWGQ 149 V R + HP Y+ + DIMLL+L R AK + +QPL L + AQ +C + GWG+ Sbjct: 68 VVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSAQTT---SCHILGWGK 124 Query: 150 TAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIE---LCVGDPEIKKTSFKGDSGGP 206 TA G T+Q + + +CE H Y I LC GD + K S +GDSGGP Sbjct: 125 TAD-GDFPDTIQCAYIHLVSREECE----HAYPGQITQNMLCAGDEKYGKDSCQGDSGGP 179 Query: 207 LVCNKVAQGIVSYGR---NNGMPPRACTKVSSFVHWIKKTMK 245 LVC +G+VS+G + P T V + +WI+KT++ Sbjct: 180 LVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQ 221 >1GVZ-A nrPDB Length = 237 Score = 120 bits (300), Expect = 7e-28, Method: Compositional matrix adjust. Identities = 83/243 (34%), Positives = 124/243 (51%), Gaps = 25/243 (10%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 IIGG E + HS+P+ + ++ Q + CGG L+ +VLTAAHC + LG HN+ Sbjct: 1 IIGGWECEKHSKPWQ--VAVYHQGHFQ-CGGVLVHPQWVLTAAHCMSDDYQIWLGRHNLS 57 Query: 81 EQEPTQQFIPVKRPIPHPAYN-----------PKNFSNDIMLLQLERKAKRTRAVQPLRL 129 + E T QF V P ++ + S+D+MLL+L + A+ T AV+ L L Sbjct: 58 KDEDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVKILDL 117 Query: 130 PSNKAQVKPGQTCSVAGWGQTAPL-GKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIE-- 186 P+ + K G TC +GWG + + S TLQ V++ +Q + KC R Y + E Sbjct: 118 PTQEP--KLGSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCA---RAYPEKMTEFV 172 Query: 187 LCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNNGMPPR---ACTKVSSFVHWIKKT 243 LC + + GDSGG L+C+ V QGI S+G + TKV WIK+T Sbjct: 173 LCATHRDDSGSICLGDSGGALICDGVFQGITSWGYSECADFNDNFVFTKVMPHKKWIKET 232 Query: 244 MKR 246 +++ Sbjct: 233 IEK 235 >1PPF-E nrPDB Length = 218 Score = 119 bits (297), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 78/232 (33%), Positives = 113/232 (48%), Gaps = 21/232 (9%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVT----LGA 76 I+GG A+PH+ P+M L + + CG LI +FV++AAHC + LGA Sbjct: 1 IVGGRRARPHAWPFMVSLQL---RGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGA 57 Query: 77 HNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQV 136 HN+ +EPT+Q V+R I Y+P N NDI++LQL A VQ +LP+ ++ Sbjct: 58 HNLSRREPTRQVFAVQR-IFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 116 Query: 137 KPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKK 196 G C GWG + LQE+ +TV S+ +C + Sbjct: 117 GNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSN----------VCTLVRGRQA 166 Query: 197 TSFKGDSGGPLVCNKVAQGIVSYGRN---NGMPPRACTKVSSFVHWIKKTMK 245 GDSG PLVCN + GI S+ R +G+ P A V+ FV+WI ++ Sbjct: 167 GVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 218 >3QUM-P nrPDB Length = 237 Score = 117 bits (294), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 82/239 (34%), Positives = 118/239 (49%), Gaps = 21/239 (8%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 I+GG E + HS+P+ + + CGG L+ +VLTAAHC + + LG H++ Sbjct: 1 IVGGWECEKHSQPWQVLVA---SRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 57 Query: 81 EQEPTQQFIPVKRPIPHPAYN-----------PKNFSNDIMLLQLERKAKRTRAVQPLRL 129 E T Q V PHP Y+ + S+D+MLL+L A+ T AV+ + L Sbjct: 58 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 117 Query: 130 PSNKAQVKPGQTCSVAGWGQTAPLGKHS-HTLQEVKMTVQEDRKCESDLRHYYDSTIELC 188 P+ + + G TC +GWG P + LQ V + V + C + + + LC Sbjct: 118 PTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVC-AQVHPQKVTKFMLC 174 Query: 189 VGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRN-NGMP--PRACTKVSSFVHWIKKTM 244 G K++ GDSGGPLVCN V QGI S+G +P P TKV + WIK T+ Sbjct: 175 AGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 233 >2R0L-A nrPDB Length = 248 Score = 115 bits (288), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 81/243 (33%), Positives = 127/243 (52%), Gaps = 22/243 (9%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG-----SSINVTLG 75 IIGG + P S P++A + I D C G L+ +V++AAHC+ S++V LG Sbjct: 1 IIGGSSSLPGSHPWLAAIYIGDS----FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLG 56 Query: 76 AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSN-DIMLLQLERK----AKRTRAVQPLRLP 130 H Q +++ IP+ Y+ N S+ D++L++L++K A R++ VQP+ LP Sbjct: 57 QHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLP 116 Query: 131 SNKAQVKPGQTCSVAGWGQ-TAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYD-STIELC 188 + G C +AGWG + +S +L+E + + D KC S + D S LC Sbjct: 117 EPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLC 176 Query: 189 VGDPEIKKTSFKGDSGGPLVC--NKVA--QGIVSYGRNNG--MPPRACTKVSSFVHWIKK 242 G + K + +GDSGGPL C N VA GI+S+G G P T+V+++V WI Sbjct: 177 AGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWIND 236 Query: 243 TMK 245 ++ Sbjct: 237 RIR 239 >1YC0-A nrPDB Length = 283 Score = 114 bits (286), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 81/244 (33%), Positives = 127/244 (52%), Gaps = 22/244 (9%) Query: 20 EIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG-----SSINVTL 74 IIGG + P S P++A + I D C G L+ +V++AAHC+ S++V L Sbjct: 35 RIIGGSSSLPGSHPWLAAIYIGDS----FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVL 90 Query: 75 GAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSN-DIMLLQLERK----AKRTRAVQPLRL 129 G H Q +++ IP+ Y+ N S+ D++L++L++K A R++ VQP+ L Sbjct: 91 GQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICL 150 Query: 130 PSNKAQVKPGQTCSVAGWGQ-TAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYD-STIEL 187 P + G C +AGWG + +S +L+E + + D KC S + D S L Sbjct: 151 PEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNML 210 Query: 188 CVGDPEIKKTSFKGDSGGPLVC--NKVA--QGIVSYGRNNGM--PPRACTKVSSFVHWIK 241 C G + K + +GDSGGPL C N VA GI+S+G G P T+V+++V WI Sbjct: 211 CAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWIN 270 Query: 242 KTMK 245 ++ Sbjct: 271 DRIR 274 >1EKB-B nrPDB Length = 235 Score = 114 bits (285), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 69/237 (29%), Positives = 116/237 (48%), Gaps = 16/237 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-WGSSIN-----VTL 74 I+GG +++ + P++ L DQ+ CG L+ D++++AAHC +G ++ L Sbjct: 1 IVGGSDSREGAWPWVVALYFDDQQV---CGASLVSRDWLVSAAHCVYGRNMEPSKWKAVL 57 Query: 75 GAHNIKE-QEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNK 133 G H P + + + + +P YN + +NDI ++ LE K T +QP+ LP Sbjct: 58 GLHMASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLPEEN 117 Query: 134 AQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPE 193 PG+ CS+AGWG G + LQE + + + KC+ + Y + +C G Sbjct: 118 QVFPPGRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQQMPEYNITENMVCAGYEA 177 Query: 194 IKKTSFKGDSGGPLVCNK----VAQGIVSYGRNNGMP--PRACTKVSSFVHWIKKTM 244 S +GDSGGPL+C + + G+ S+G +P P +V F WI+ + Sbjct: 178 GGVDSCQGDSGGPLMCQENNRWLLAGVTSFGYQCALPNRPGVYARVPRFTEWIQSFL 234 >1AE5-A nrPDB Length = 225 Score = 114 bits (285), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 74/230 (32%), Positives = 111/230 (48%), Gaps = 17/230 (7%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSS----INVTLGA 76 I+GG +A+P P++A + + CGG LI FV+TAA C+ S V LGA Sbjct: 1 IVGGRKARPRQFPFLASI---QNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA 57 Query: 77 HNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQV 136 ++++ +E + + Y+P+ ND+MLLQL+R+A T +V L LP A V Sbjct: 58 YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 117 Query: 137 KPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKK 196 + G C VAGWG G+ S + V +TV + +C + +C G + Sbjct: 118 EAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPN---------NVCTGVLTRRG 168 Query: 197 TSFKGDSGGPLVCNKVAQGIVSYGRN-NGMPPRACTKVSSFVHWIKKTMK 245 GD G PLVC +A G+ S+ G P T+V+ F WI + Sbjct: 169 GICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLN 218 >1FXY-A nrPDB Length = 228 Score = 113 bits (282), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 76/229 (33%), Positives = 115/229 (50%), Gaps = 10/229 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW--GSSINVTLGAHN 78 I+GG+ K P+ A L+ ++++ CGG ++ + ++LTAAHC V +G N Sbjct: 1 IVGGYNCKDGEVPWQALLI--NEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRN 58 Query: 79 IKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKP 138 +++E + V+ I H + + + DI +L+L+ V P LP+ A Sbjct: 59 TEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLPT--APPAT 116 Query: 139 GQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKT 197 G C ++GWG TA G + LQ + V KCE+ S + CVG E K Sbjct: 117 GTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNM-FCVGFLEGGKD 175 Query: 198 SFKGDSGGPLVCNKVAQGIVSYGRNNGM--PPRACTKVSSFVHWIKKTM 244 S +GDSGGP+VCN QG+VS+G P TKV ++V WIK T+ Sbjct: 176 SCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTI 224 >3W94-A nrPDB Length = 235 Score = 112 bits (281), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 79/240 (32%), Positives = 121/240 (50%), Gaps = 20/240 (8%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-WGSSINV-----TL 74 ++GG A+ + P+M L + CG LI D++LTAAHC +G + ++ L Sbjct: 1 VVGGVNAEKGAWPWMVSL---HWRGRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVL 57 Query: 75 GAH---NIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPS 131 G H ++ QE Q V R I + YN + DI ++ L++ T V P+ L S Sbjct: 58 GLHAQSSMNSQEV--QIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLAS 115 Query: 132 NKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGD 191 G+ C +AGWG+ A G LQE ++ + + +C+ L Y ++ LC G Sbjct: 116 EDQHFPAGRRCFIAGWGRDAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTSSMLCAGY 175 Query: 192 PEIKKTSFKGDSGGPLVCNKVAQ----GIVSYGRNNGMP--PRACTKVSSFVHWIKKTMK 245 PE S +GDSGGPL+C + A+ G+ S+G G P P A +VS+F WI +T + Sbjct: 176 PEGGVDSCQGDSGGPLMCLEDARWTLIGVTSFGVGCGRPERPGAYARVSAFTSWIAETRR 235 >5UGG-A nrPDB Length = 251 Score = 112 bits (280), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 87/245 (35%), Positives = 115/245 (46%), Gaps = 23/245 (9%) Query: 14 PRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG-----S 68 P+ G ++GG A PHS P+ L + + CGG LI ++VLTAAHC S Sbjct: 15 PKKCPGRVVGGCVAHPHSWPWQVSLRT--RFGMHFCGGTLISPEWVLTAAHCLEKSPRPS 72 Query: 69 SINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLR 128 S V LGAH EP Q I V R P DI LL+L A T V P Sbjct: 73 SYKVILGAHQEVNLEPHVQEIEVSRLFLEPT------RKDIALLKLSSPAVITDKVIPAC 126 Query: 129 LPSNKAQVKPGQTCSVAGWGQT-APLGKHSHTLQEVKMTVQEDRKCES-DLRHYYDSTIE 186 LPS V C + GWG+T G + L+E ++ V E++ C + + + E Sbjct: 127 LPSPNYVVADRTECFITGWGETQGTFG--AGLLKEAQLPVIENKVCNRYEFLNGRVQSTE 184 Query: 187 LCVGDPEIKKTSFKGDSGGPLVCNK----VAQGIVSYGRNNGMP--PRACTKVSSFVHWI 240 LC G S +GDSGGPLVC + + QG+ S+G P P +VS FV WI Sbjct: 185 LCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWI 244 Query: 241 KKTMK 245 + M+ Sbjct: 245 EGVMR 249 >2V35-A nrPDB Length = 240 Score = 111 bits (277), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 73/240 (30%), Positives = 118/240 (49%), Gaps = 19/240 (7%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKR-CGGFLIRDDFVLTAAHCWGSSIN--VTLGAH 77 ++GG EA+ +S P L S CGG LIR ++V+TAAHC + V +G H Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEH 60 Query: 78 NIKEQEPTQQFIPVKRPIPHPAYNPKNFSN--DIMLLQLERKAKRTRAVQPLRLPSNKAQ 135 N+ + + T+Q++ V++ + HP +N + + DI LL+L + VQ LP Sbjct: 61 NLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRAGTI 120 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIE---LCVGDP 192 + C + GWG T G+ + TLQ+ + + C S Y+ ST++ +C G Sbjct: 121 LANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSS--SYWGSTVKNSMVCAGGD 178 Query: 193 EIKKTSFKGDSGGPLVC----NKVAQGIVSY----GRNNGMPPRACTKVSSFVHWIKKTM 244 + ++ +GDSGGPL C G+ S+ G N P T+VS+++ WI + Sbjct: 179 GV-RSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNVI 237 >2AIQ-A nrPDB Length = 231 Score = 110 bits (275), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 76/231 (32%), Positives = 116/231 (50%), Gaps = 15/231 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 +IGG E + ++A +++ SL CGG LI ++VLTA HC ++ + LG HN+K Sbjct: 1 VIGGDECNINEHRFLA--LVYANGSL--CGGTLINQEWVLTARHCDRGNMRIYLGMHNLK 56 Query: 81 --EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKP 138 ++ ++F P ++ N + DIML++L R + + + PL LPSN V Sbjct: 57 VLNKDALRRF-PKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPSNPPSV-- 113 Query: 139 GQTCSVAGWGQ-TAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKT 197 G C + GWG T+P + + + C++ + +T LC G E K Sbjct: 114 GSVCRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAYKGLAATT--LCAGILEGGKD 171 Query: 198 SFKGDSGGPLVCNKVAQGIVSYGRNNGMPPR---ACTKVSSFVHWIKKTMK 245 + KGDSGGPL+CN QGI+S G N PR TKV + WI+ + Sbjct: 172 TCKGDSGGPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSIIS 222 >1X7A-C nrPDB Length = 235 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 81/238 (34%), Positives = 119/238 (50%), Gaps = 18/238 (7%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW--GSSINVTLGAHN 78 I+GG AKP P+ L + K CGG +I + +V+TAAHC G I V G +N Sbjct: 1 IVGGENAKPGQFPWQVLL---NGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVAGEYN 57 Query: 79 IKEQEPTQQFIPVKRPIPHPAYNP--KNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ- 135 +E EPT+Q V R IPH +YN +S+DI LL+L+ V P+ + + Sbjct: 58 TEETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEYTN 117 Query: 136 --VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPE 193 +K G + V+GWG+ G+ + LQ +K+ + + C + S + C G E Sbjct: 118 IFLKFG-SGYVSGWGRVFNRGRSATILQYLKVPLVDRATCLRSTKFTIYSNM-FCAGFHE 175 Query: 194 IKKTSFKGDSGGPLVC----NKVAQGIVSYGRNNGMPPR--ACTKVSSFVHWIKKTMK 245 K S +GDSGGP V GI+S+G + + TKVS +V+WIK+ K Sbjct: 176 GGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAVKGKYGIYTKVSRYVNWIKEKTK 233 >1BRU-P nrPDB Length = 241 Score = 109 bits (272), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 78/244 (31%), Positives = 115/244 (47%), Gaps = 22/244 (9%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKR--CGGFLIRDDFVLTAAHCWGSS--INVTLGA 76 ++GG +A+P+S P+ L +D R CGG L+ +VLTAAHC SS V LG Sbjct: 1 VVGGEDARPNSWPWQVSLQ-YDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGR 59 Query: 77 HNIKEQEPTQQFIPVKRPIPHPAYNPKNFSN--DIMLLQLERKAKRTRAVQPLRLPSNKA 134 H++ EP + V + + H +N SN DI LL+L T +Q LP+ Sbjct: 60 HSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAGT 119 Query: 135 QVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIE---LCVGD 191 + C V GWG+ G LQ+ ++ V + C ++ ST++ +C G Sbjct: 120 ILPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKP--GWWGSTVKTNMICAGG 177 Query: 192 PEIKKTSFKGDSGGPLVCNKV-----AQGIVSYGRNNGM----PPRACTKVSSFVHWIKK 242 I +S GDSGGPL C GIVS+G + G P T+VS+++ WI Sbjct: 178 DGI-ISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINS 236 Query: 243 TMKR 246 + Sbjct: 237 VIAN 240 >4DUR-A nrPDB Length = 791 Score = 108 bits (270), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 87/245 (35%), Positives = 115/245 (46%), Gaps = 23/245 (9%) Query: 14 PRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG-----S 68 P+ G ++GG A PHS P+ L + + CGG LI ++VLTAAHC S Sbjct: 555 PKKCPGRVVGGCVAHPHSWPWQVSLRT--RFGMHFCGGTLISPEWVLTAAHCLEKSPRPS 612 Query: 69 SINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLR 128 S V LGAH EP Q I V R P DI LL+L A T V P Sbjct: 613 SYKVILGAHQEVNLEPHVQEIEVSRLFLEPT------RKDIALLKLSSPAVITDKVIPAC 666 Query: 129 LPSNKAQVKPGQTCSVAGWGQT-APLGKHSHTLQEVKMTVQEDRKCES-DLRHYYDSTIE 186 LPS V C + GWG+T G + L+E ++ V E++ C + + + E Sbjct: 667 LPSPNYVVADRTECFITGWGETQGTFG--AGLLKEAQLPVIENKVCNRYEFLNGRVQSTE 724 Query: 187 LCVGDPEIKKTSFKGDSGGPLVCNK----VAQGIVSYGRNNGMP--PRACTKVSSFVHWI 240 LC G S +GDSGGPLVC + + QG+ S+G P P +VS FV WI Sbjct: 725 LCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWI 784 Query: 241 KKTMK 245 + M+ Sbjct: 785 EGVMR 789 >2CGA-A nrPDB Length = 245 Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 75/255 (29%), Positives = 123/255 (48%), Gaps = 29/255 (11%) Query: 1 MQPILLLLAFLLLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVL 60 +QP+L L+ I+ G EA P S P+ L D+ CGG LI +++V+ Sbjct: 6 IQPVLSGLS----------RIVNGEEAVPGSWPWQVSLQ--DKTGFHFCGGSLINENWVV 53 Query: 61 TAAHCWGSSINVTL-GAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAK 119 TAAHC ++ +V + G + Q + + + + YN +NDI LL+L A Sbjct: 54 TAAHCGVTTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAAS 113 Query: 120 RTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHS-HTLQEVKMTVQEDRKCESDLR 178 ++ V + LPS G TC GWG T ++ LQ+ + + + C + Sbjct: 114 FSQTVSAVCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNC----K 169 Query: 179 HYYDSTIE---LCVGDPEIKKTSFKGDSGGPLVCNKVAQ----GIVSYGRN--NGMPPRA 229 Y+ + I+ +C G + +S GDSGGPLVC K GIVS+G + + P Sbjct: 170 KYWGTKIKDAMICAGASGV--SSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGV 227 Query: 230 CTKVSSFVHWIKKTM 244 +V++ V+W+++T+ Sbjct: 228 YARVTALVNWVQQTL 242 >1ELT-A nrPDB Length = 236 Score = 107 bits (268), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 74/240 (30%), Positives = 113/240 (47%), Gaps = 20/240 (8%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSL-KRCGGFLIRDDFVLTAAHCWGS--SINVTLGAH 77 ++GG A+P+S P+ L S CGG LIR +V+TAAHC S + V LG H Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSARTWRVVLGEH 60 Query: 78 NIKEQEPTQQFIPVKRPIPHPAYNPKNFSN--DIMLLQLERKAKRTRAVQPLRLPSNKAQ 135 N+ E +Q + V H +N + + DI LL+L +A AVQ LP + Sbjct: 61 NLNTNEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPSNQI 120 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIE---LCVGDP 192 + C + GWG+T+ G S +L++ + + C S ++ ST++ +C G Sbjct: 121 LPNNNPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSSS--GWWGSTVKTTMVCAGGG 178 Query: 193 EIKKTSFKGDSGGPLVC--------NKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTM 244 + GDSGGPL C + V + S G N P T+VS+++ W+ M Sbjct: 179 A--NSGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAYISWMNGIM 236 >4MPW-A nrPDB Length = 245 Score = 107 bits (267), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 78/250 (31%), Positives = 116/250 (46%), Gaps = 31/250 (12%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG------SSINVTL 74 I+GG EA P+ L + + CGG LI +VLTAAHC G +++ V L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 60 Query: 75 GAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKA 134 ++ Q+ Q +PV R I HP + DI LL+LE K + V + LP Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASE 117 Query: 135 QVKPGQTCSVAGWGQTAPLGK--HSHTLQEVKMTVQEDRKCES----------DLRHYYD 182 PG C V GWG + L++VK+ + E+ C++ D+R D Sbjct: 118 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 177 Query: 183 STIELCVGDPEIKKTSFKGDSGGPLVC----NKVAQGIVSYGRNNGMP--PRACTKVSSF 236 LC G+ ++ S +GDSGGPLVC + G+VS+G P P T+V+ + Sbjct: 178 DM--LCAGN--TRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYY 233 Query: 237 VHWIKKTMKR 246 + WI + + Sbjct: 234 LDWIHHYVPK 243 >1EQ9-A nrPDB Length = 222 Score = 107 bits (266), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 75/232 (32%), Positives = 113/232 (48%), Gaps = 16/232 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG--SSIN---VTLG 75 I+GG +A PY L + RCG ++ ++ VLTAAHC S++N V +G Sbjct: 1 IVGGKDAPVGKYPYQVSLRL---SGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVG 57 Query: 76 AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ 135 + + E + V+ + + Y+ ND+ L+ L K VQP++L +N Sbjct: 58 TNYLSE---SGDVYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTNDED 114 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIK 195 ++ C++ GWG T G + LQE+++ V ++CE D DS I E Sbjct: 115 LES-NPCTLTGWGSTRLGGNTPNALQEIELIVHPQKQCERDQWRVIDSHICTLTKRGE-- 171 Query: 196 KTSFKGDSGGPLVCNKVAQGIVSYGRNNGM-PPRACTKVSSFVHWIKKTMKR 246 + GDSGGPLV N GIVS+G + P T+VSSFV WI +K+ Sbjct: 172 -GACHGDSGGPLVANGAQIGIVSFGSPCALGEPDVYTRVSSFVSWINANLKK 222 >1LTO-A nrPDB Length = 245 Score = 107 bits (266), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 80/251 (31%), Positives = 117/251 (46%), Gaps = 33/251 (13%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG------SSINVTL 74 I+GG EA P+ L + D+ + CGG LI +VLTAAHC G +++ V L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQL 60 Query: 75 GAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKA 134 ++ Q+ Q +PV R I HP + DI LL+LE + V + LP Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPASE 117 Query: 135 QVKPGQTCSVAGWGQT---APLGKHSHTLQEVKMTVQEDRKCES----------DLRHYY 181 PG C V GWG PL L++VK+ + E+ C++ D+R Sbjct: 118 TFPPGMPCWVTGWGDVDNDEPLPP-PFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIIR 176 Query: 182 DSTIELCVGDPEIKKTSFKGDSGGPLVC----NKVAQGIVSYGRNNGMP--PRACTKVSS 235 D LC G+ + + S KGDSGGPLVC + G+VS+ P P T+V+ Sbjct: 177 DDM--LCAGNSQ--RDSCKGDSGGPLVCKVNGTWLQAGVVSWDEGCAQPNRPGIYTRVTY 232 Query: 236 FVHWIKKTMKR 246 ++ WI + + Sbjct: 233 YLDWIHHYVPK 243 >3E0N-B nrPDB Length = 271 Score = 104 bits (260), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 76/247 (30%), Positives = 113/247 (45%), Gaps = 25/247 (10%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGS-----SINVTLG 75 I GG A P+ + + + CGG L+ + +VL+AAHC+ S + V LG Sbjct: 1 ITGGSSAVAGQWPWQVSITY---EGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLG 57 Query: 76 AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ 135 AH + + +K IPHP+Y + DI LLQL R +R ++P+ LP+ +A Sbjct: 58 AHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQAS 117 Query: 136 VKPGQTCSVAGWGQTAPLGK--HSHTLQEVKMTVQEDRKCES--------DLRHYYDSTI 185 G C+V GWG AP LQ++++ + C S + H+ + Sbjct: 118 FPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQEDM 177 Query: 186 ELCVGDPEIKKTSFKGDSGGPLVCNKVA----QGIVSYGRNNGM--PPRACTKVSSFVHW 239 +C G E K + +GDSGGPL C GIVS+G G P T SS+ W Sbjct: 178 -VCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASW 236 Query: 240 IKKTMKR 246 I+ + Sbjct: 237 IQSKVTE 243 >1P57-B nrPDB Length = 255 Score = 104 bits (259), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 77/250 (30%), Positives = 114/250 (45%), Gaps = 28/250 (11%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVT----LGA 76 I+GG + P+ L +D L CGG L+ D+VLTAAHC+ V + A Sbjct: 1 IVGGRDTSLGRWPWQVSLR-YDGAHL--CGGSLLSGDWVLTAAHCFPERNRVLSRWRVFA 57 Query: 77 HNIKEQEPTQQFIPVKRPIPHPAY------NPKNFSNDIMLLQLERKAKRTRAVQPLRLP 130 + + P + V+ + H Y N + SNDI L+ L T +QP+ LP Sbjct: 58 GAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLP 117 Query: 131 SNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIE---L 187 + + G+ C+V GWG T G+ + LQE ++ + + C +Y + I+ Sbjct: 118 AAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNG--ADFYGNQIKPKMF 175 Query: 188 CVGDPEIKKTSFKGDSGGPLVCNKVAQ--------GIVSYGRNNGMP--PRACTKVSSFV 237 C G PE + +GDSGGP VC GIVS+G + P TKVS F Sbjct: 176 CAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFR 235 Query: 238 HWIKKTMKRY 247 WI + +K + Sbjct: 236 EWIFQAIKTH 245 >3T2N-A nrPDB Length = 372 Score = 104 bits (259), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 77/250 (30%), Positives = 114/250 (45%), Gaps = 28/250 (11%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVT----LGA 76 I+GG + P+ L +D L CGG L+ D+VLTAAHC+ V + A Sbjct: 118 IVGGRDTSLGRWPWQVSLR-YDGAHL--CGGSLLSGDWVLTAAHCFPERNRVLSRWRVFA 174 Query: 77 HNIKEQEPTQQFIPVKRPIPHPAY------NPKNFSNDIMLLQLERKAKRTRAVQPLRLP 130 + + P + V+ + H Y N + SNDI L+ L T +QP+ LP Sbjct: 175 GAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLP 234 Query: 131 SNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIE---L 187 + + G+ C+V GWG T G+ + LQE ++ + + C +Y + I+ Sbjct: 235 AAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNG--ADFYGNQIKPKMF 292 Query: 188 CVGDPEIKKTSFKGDSGGPLVCNKVAQ--------GIVSYGRNNGMP--PRACTKVSSFV 237 C G PE + +GDSGGP VC GIVS+G + P TKVS F Sbjct: 293 CAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFR 352 Query: 238 HWIKKTMKRY 247 WI + +K + Sbjct: 353 EWIFQAIKTH 362 >1PYT-D nrPDB Length = 251 Score = 104 bits (259), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 74/243 (30%), Positives = 117/243 (48%), Gaps = 18/243 (7%) Query: 18 AGEIIGGHEAKPHSRPYMAYLM-IWDQKSLKRCGGFLIRDDFVLTAAHCWGSSIN--VTL 74 + ++GG +A PHS P+ L + D CGG LI + VLTAAHC +++ V L Sbjct: 11 SARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCISNTLTYRVAL 70 Query: 75 GAHNIK-EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNK 133 G +N++ E E ++ V H +N NDI L++L + +Q LPS Sbjct: 71 GKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELGDTIQVACLPSEG 130 Query: 134 AQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIE---LCVG 190 + + C V GWG+ G + LQ+ V + C R ++ +T++ +C G Sbjct: 131 SLLPQDYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQ--RDWWGTTVKETMVCAG 188 Query: 191 DPEIKKTSFKGDSGGPLVCNKVAQ----GIVSYGR----NNGMPPRACTKVSSFVHWIKK 242 + ++ GDSGGPL C Q GIVS+G N P T+VS+++ WI + Sbjct: 189 GDGV-ISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPTVFTRVSAYIDWINQ 247 Query: 243 TMK 245 ++ Sbjct: 248 KLQ 250 >3LC3-A nrPDB Length = 235 Score = 104 bits (259), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 76/238 (31%), Positives = 119/238 (50%), Gaps = 18/238 (7%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC--WGSSINVTLGAHN 78 ++GG +AKP P+ L + K CGG ++ + +++TAAHC G I V G HN Sbjct: 1 VVGGEDAKPGQFPWQVVL---NGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHN 57 Query: 79 IKEQEPTQQFIPVKRPIPHPAYNP--KNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ- 135 I+E E T+Q V R IPH YN +++DI LL+L+ V P+ + + Sbjct: 58 IEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTN 117 Query: 136 --VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPE 193 +K G + V+GWG+ G+ + LQ +++ + + C + + + C G E Sbjct: 118 IFLKFG-SGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNM-FCAGFHE 175 Query: 194 IKKTSFKGDSGGPLVC----NKVAQGIVSYGRNNGMPPR--ACTKVSSFVHWIKKTMK 245 + S +GDSGGP V GI+S+G M + TKVS +V+WIK+ K Sbjct: 176 GGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK 233 >3DFJ-A nrPDB Length = 263 Score = 103 bits (257), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 75/247 (30%), Positives = 112/247 (45%), Gaps = 25/247 (10%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGS-----SINVTLG 75 I GG A P+ + + + CGG L+ + +VL+AAHC+ S + V LG Sbjct: 1 ITGGSSAVAGQWPWQVSITY---EGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLG 57 Query: 76 AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ 135 AH + + +K IPHP+Y + DI LLQL R +R ++P+ LP+ A Sbjct: 58 AHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAANAS 117 Query: 136 VKPGQTCSVAGWGQTAPLGK--HSHTLQEVKMTVQEDRKCES--------DLRHYYDSTI 185 G C+V GWG AP LQ++++ + C + + H+ + Sbjct: 118 FPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFVQEDM 177 Query: 186 ELCVGDPEIKKTSFKGDSGGPLVCNKVA----QGIVSYGRNNGM--PPRACTKVSSFVHW 239 +C G E K + +GDSGGPL C GIVS+G G P T SS+ W Sbjct: 178 -VCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASW 236 Query: 240 IKKTMKR 246 I+ + Sbjct: 237 IQSKVTE 243 >2F91-A nrPDB Length = 237 Score = 103 bits (257), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 75/237 (31%), Positives = 108/237 (45%), Gaps = 20/237 (8%) Query: 21 IIGGHEAKPHSRPY-MAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-WG------SSINV 72 I+GG +A PY +++ + S CG + +++ +TA HC +G S + + Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 73 TLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSN 132 G ++ E ++Q I V + I H ++ NDI LL+L V P+ LP Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALPE- 119 Query: 133 KAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDL--RHYYDSTIELCVG 190 + G V GWG T+ G LQ+V + + D C +D DS I C G Sbjct: 120 QGHTATGDVI-VTGWGTTSEGGNTPDVLQKVTVPLVSDEDCRADYGADEILDSMI--CAG 176 Query: 191 DPEIKKTSFKGDSGGPLVCNKVAQ----GIVSYGRNNGMP--PRACTKVSSFVHWIK 241 PE K S +GDSGGPL + GIVS+G P P T+VS V WIK Sbjct: 177 VPEGGKDSCQGDSGGPLAASDTGSTYLAGIVSWGYGCARPGYPGVYTEVSYHVDWIK 233 >4GSO-A nrPDB Length = 232 Score = 102 bits (255), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 72/229 (31%), Positives = 108/229 (47%), Gaps = 12/229 (5%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 ++GG E + P++A+L CG LI ++V+TAAHC ++ + LG H+ K Sbjct: 1 VLGGDECDINEHPFLAFLY----SHGYFCGLTLINQEWVVTAAHCDSTNFQMQLGVHSKK 56 Query: 81 EQEPTQQFIPVKRPIPHPAYN-PKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 +Q K P N + DIML++L++ ++ + PL LPSN V G Sbjct: 57 VLNEDEQTRNPKEKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPSNPPSV--G 114 Query: 140 QTCSVAGWGQ-TAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTS 198 C + GWG T P + + + + C+ T LC G E K + Sbjct: 115 SVCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLPAKTT-LCAGVLEGGKDT 173 Query: 199 FKGDSGGPLVCNKVAQGIVSYGRNN---GMPPRACTKVSSFVHWIKKTM 244 GDSGGPL+CN QGIVSYG ++ G P T V + WI++ + Sbjct: 174 CVGDSGGPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNI 222 >4H4F-A nrPDB Length = 249 Score = 101 bits (252), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 72/239 (30%), Positives = 112/239 (46%), Gaps = 15/239 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKR-CGGFLIRDDFVLTAAHCWGSS--INVTLGAH 77 ++GG +A+PHS P+ L + + CGG LI +FVLTAAHC ++ V +G + Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 60 Query: 78 NIK-EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQV 136 N++ E E F+ V H +N NDI L++L + + +Q LP + + Sbjct: 61 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 120 Query: 137 KPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCES-DLRHYYDSTIELCVGDPEIK 195 C V GWG+ G + LQ+ V + C D + +C G + Sbjct: 121 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGV- 179 Query: 196 KTSFKGDSGGPLVC-----NKVAQGIVSYGRNNGM----PPRACTKVSSFVHWIKKTMK 245 ++ GDSGGPL C + GIVS+G G P T+VS+++ WI + M+ Sbjct: 180 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 238 >4E7N-A nrPDB Length = 238 Score = 98.6 bits (244), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 75/231 (32%), Positives = 114/231 (49%), Gaps = 10/231 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 IIGG E + ++ L ++L CGG LI ++VLTAAHC + + LG H+ K Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRTL-FCGGTLINQEWVLTAAHCDRKNFRIKLGMHSKK 59 Query: 81 -EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 E Q +P ++ + N + DIML++L+ K ++ + P LPS+ V G Sbjct: 60 VPNEDEQTRVPKEKFFCLSSKNYTLWDKDIMLIRLDSPVKNSKHIAPFSLPSSPPSV--G 117 Query: 140 QTCSVAGWGQTAPL-GKHSHTLQEVKMTVQEDRKCESDLRHYY--DSTIELCVGDPEIKK 196 C + GWG+ +P G + V + + E C + + ++ LC G E K Sbjct: 118 SVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCAGILEGGK 177 Query: 197 TSFKGDSGGPLVCNKVAQGIVSYGRNNGMPPR---ACTKVSSFVHWIKKTM 244 + KGDSGGPL+CN QGI S+G + P A TKV + WI+ + Sbjct: 178 DTCKGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENII 228 >5XW8-A nrPDB Length = 133 Score = 97.4 bits (241), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 51/138 (36%), Positives = 69/138 (50%), Gaps = 6/138 (4%) Query: 13 LPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINV 72 P D +I+GG+ +S PY L CGG LI +V++AAHC+ S I V Sbjct: 1 FPTDDDDKIVGGYTCAANSIPYQVSL----NSGSHFCGGSLINSQWVVSAAHCYKSRIQV 56 Query: 73 TLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSN 132 LG HNI E +QFI + I HP +N NDIML++L A V + LP Sbjct: 57 RLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLP-- 114 Query: 133 KAQVKPGQTCSVAGWGQT 150 ++ G C ++GWG T Sbjct: 115 RSCAAAGTECLISGWGNT 132 >5TJX-A nrPDB Length = 263 Score = 97.1 bits (240), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 68/231 (29%), Positives = 103/231 (44%), Gaps = 11/231 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG-----SSINVTLG 75 I+GG E+ P+ L + CGG LI +VLTAAHC+ + G Sbjct: 16 IVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 75 Query: 76 AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ 135 + + F +K I H Y ++DI L++L+ + T +P+ LPS Sbjct: 76 ILELSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLEYTEFQKPISLPSKGDT 135 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIK 195 C V GWG + G+ + LQ+V + + + +C+ + Y + +C G E Sbjct: 136 STIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 195 Query: 196 KTSFKGDSGGPLVCNKVAQ----GIVSYGRNNGM--PPRACTKVSSFVHWI 240 K + KGDSGGPLVC GI S+G P TKV+ ++ WI Sbjct: 196 KDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 246 >3S69-A nrPDB Length = 234 Score = 96.7 bits (239), Expect = 9e-21, Method: Compositional matrix adjust. Identities = 73/232 (31%), Positives = 113/232 (48%), Gaps = 16/232 (6%) Query: 21 IIGGHEAKPHS-RPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHN- 78 +IGG E + R +A+ + C G LI +++VLTAAHC ++ + LG H+ Sbjct: 1 VIGGDECNINEHRSLVAFF----NSTGFFCSGTLINEEWVLTAAHCDNTNFQMKLGVHSK 56 Query: 79 --IKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQV 136 + E E T+ P ++ I N + DIML++L+ + + + PL LPS+ V Sbjct: 57 KVLNEDEQTRN--PKEKFICPNKKNDEVLDKDIMLIKLDSRVSNSEHIVPLSLPSSPPSV 114 Query: 137 KPGQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIK 195 G C + GWG P+ + + + +D C++ LC G E Sbjct: 115 --GSVCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGILEGG 172 Query: 196 KTSFKGDSGGPLVCNKVAQGIVSYGRN---NGMPPRACTKVSSFVHWIKKTM 244 K + GDSGGPL+CN QGIVS+G + G+ P TKV + HWI+ + Sbjct: 173 KDTCGGDSGGPLICNGQFQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSII 224 >4XDE-A nrPDB Length = 257 Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 79/245 (32%), Positives = 115/245 (46%), Gaps = 29/245 (11%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGS-----SINVTLG 75 ++GG A + PY+A L W C G LI +VLTAAHC + V LG Sbjct: 3 VVGGLVALRGAHPYIAALY-WGHS---FCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLG 58 Query: 76 AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRA-----VQPLRLP 130 Q + V+ H A++P ++ +D+ LL+L+ A + A VQP+ LP Sbjct: 59 QERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSLP 118 Query: 131 SNKAQVKPGQTCSVAGWG-QTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTI---E 186 S A+ C VAGWG Q +++ LQE ++ +C + H S+I Sbjct: 119 SGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVH--GSSILPGM 176 Query: 187 LCVGDPEIKKTSFKGDSGGPLVCNKVA-------QGIVSYGRNNG--MPPRACTKVSSFV 237 LC G E + +GDSGGPLVC A QGI+S+G G P T V+ ++ Sbjct: 177 LCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYYL 236 Query: 238 HWIKK 242 WI++ Sbjct: 237 AWIRE 241 >2QY0-B nrPDB Length = 242 Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 81/248 (32%), Positives = 115/248 (46%), Gaps = 30/248 (12%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW---------GSSIN 71 IIGG +AK + P+ + I R GG L+ D ++LTAAH +S++ Sbjct: 1 IIGGQKAKMGNFPWQVFTNI-----HGRGGGALLGDRWILTAAHTLYPKEHEAQSNASLD 55 Query: 72 VTLGAHNIKEQEPTQQFIPVKRPIPHPAY---NPKNFSNDIMLLQLERKAKRTRAVQPLR 128 V LG N++E P++R HP Y NF DI LL+LE + P+ Sbjct: 56 VFLGHTNVEELMKLGNH-PIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPIC 114 Query: 129 LPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLR--HYYD--ST 184 LP N G V+G+G K +H L+ V++ V + CE+ LR + D S Sbjct: 115 LPDNDTFYDLGLMGYVSGFGVMEE--KIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQ 172 Query: 185 IELCVGDPEIKKTSFKGDSGGPLVCNK------VAQGIVSYGRNNGMPPRACTKVSSFVH 238 C G P +K+ + +GDSGG VA GIVS+G TKV ++V Sbjct: 173 NMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRGYGFYTKVLNYVD 232 Query: 239 WIKKTMKR 246 WIKK M+ Sbjct: 233 WIKKEMEE 240 >5GVT-A nrPDB Length = 250 Score = 95.9 bits (237), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 69/234 (29%), Positives = 101/234 (43%), Gaps = 17/234 (7%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSS--------INV 72 I+GG A P+ L + CGG +I +VLTAAHC+ Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 73 TLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSN 132 L I ++ P+ + +K I H Y + DI L++L+ T +P+ LPS Sbjct: 61 ILSLSEITKETPSSR---IKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSK 117 Query: 133 KAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDP 192 C V GWG T G+ + LQ+ + + + +C+ R Y + +C G Sbjct: 118 ADTNTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYRDYVINKQMICAGYK 177 Query: 193 EIKKTSFKGDSGGPLVCNKVAQ----GIVSYGRNNGMP--PRACTKVSSFVHWI 240 E + KGDSGGPLVC + GI S+G P TKVS ++ WI Sbjct: 178 EGGTDACKGDSGGPLVCKHSGRWQLVGITSWGEGCARKDQPGVYTKVSEYMDWI 231 >6I44-A nrPDB Length = 627 Score = 95.5 bits (236), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 67/231 (29%), Positives = 104/231 (45%), Gaps = 11/231 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG-----SSINVTLG 75 I+GG ++ P+ L + CGG LI +VLTAAHC+ + G Sbjct: 380 IVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSG 439 Query: 76 AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ 135 + + F +K I H Y ++DI L++L+ + T +P+ LPS Sbjct: 440 ILQLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLQYTEFQKPICLPSKGDT 499 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIK 195 C V GWG +A G+ + LQ+V + + + +C+ + Y + +C G E Sbjct: 500 STIYTNCWVTGWGFSAEAGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGG 559 Query: 196 KTSFKGDSGGPLVCNKVAQ----GIVSYGRNNGM--PPRACTKVSSFVHWI 240 K + KGD+GGPLVC GI S+G P TKV+ ++ WI Sbjct: 560 KDACKGDAGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 610 >5LHN-A nrPDB Length = 247 Score = 94.4 bits (233), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 78/247 (31%), Positives = 118/247 (47%), Gaps = 30/247 (12%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLK---RCGGFLIRDDFVLTAAHCW-----GSSINV 72 I+GG + ++P+ A + ++ +CGG LI +V +AAHC+ + V Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 73 TLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKN--FSNDIMLLQLERK----AKRTRAVQP 126 LG P + V++ I H Y + + NDI LL++ A+ +R++Q Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQT 120 Query: 127 LRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTL--QEVKMTVQEDRKCESDLR-HYYDS 183 + LP G C + G+G+ + S L + +KM+V + E ++ HYY S Sbjct: 121 IALPPRFTDAPFGSDCEITGFGKES----ESDYLYPKNLKMSVVKLVSHEQCMQPHYYGS 176 Query: 184 TIE---LCVGDPEIKKTSFKGDSGGPLVCN----KVAQGIVSYGRN--NGMPPRACTKVS 234 I LC DPE K S KGDSGGPL+CN GIVS+GR P T+VS Sbjct: 177 EINYKMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWGRGCAEKNKPGVYTRVS 236 Query: 235 SFVHWIK 241 F+ WI+ Sbjct: 237 HFLDWIQ 243 >1GPZ-A nrPDB Length = 399 Score = 94.4 bits (233), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 82/249 (32%), Positives = 117/249 (46%), Gaps = 30/249 (12%) Query: 20 EIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW---------GSSI 70 +IIGG +AK + P+ + I R GG L+ D ++LTAAH +S+ Sbjct: 157 QIIGGQKAKMGNFPWQVFTNI-----HGRGGGALLGDRWILTAAHTLYPKEHEAQSNASL 211 Query: 71 NVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPK---NFSNDIMLLQLERKAKRTRAVQPL 127 +V LG N++E P++R HP Y NF DI LL+LE + P+ Sbjct: 212 DVFLGHTNVEELMKLGNH-PIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPI 270 Query: 128 RLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLR--HYYD--S 183 LP N G V+G+G K +H L+ V++ V + CE+ LR + D S Sbjct: 271 CLPDNDTFYDLGLMGYVSGFGVMEE--KIAHDLRFVRLPVANPQACENWLRGKNRMDVFS 328 Query: 184 TIELCVGDPEIKKTSFKGDSGG------PLVCNKVAQGIVSYGRNNGMPPRACTKVSSFV 237 C G P +K+ + +GDSGG P VA GIVS+G TKV ++V Sbjct: 329 QNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRGYGFYTKVLNYV 388 Query: 238 HWIKKTMKR 246 WIKK M+ Sbjct: 389 DWIKKEMEE 397 >2F83-A nrPDB Length = 625 Score = 93.6 bits (231), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 72/231 (31%), Positives = 102/231 (44%), Gaps = 11/231 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSS-----INVTLG 75 I+GG + P+ L CGG +I + ++LTAAHC+ + V G Sbjct: 388 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 447 Query: 76 AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ 135 N E + F V+ I H Y DI LL+LE T + +P+ LPS + Sbjct: 448 ILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGDR 507 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIK 195 C V GWG K +TLQ+ K+ + + +C+ R + + +C G E Sbjct: 508 NVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGG 567 Query: 196 KTSFKGDSGGPLVC--NKVAQ--GIVSYGRNNGMPPR--ACTKVSSFVHWI 240 K + KGDSGGPL C N+V GI S+G R T V +V WI Sbjct: 568 KDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWI 618 >1MD7-A nrPDB Length = 328 Score = 93.2 bits (230), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 81/247 (32%), Positives = 116/247 (46%), Gaps = 30/247 (12%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW---------GSSIN 71 IIGG +AK + P+ + I R GG L+ D ++LTAAH +S++ Sbjct: 90 IIGGQKAKMGNFPWQVFTNI-----HGRGGGALLGDRWILTAAHTLYPKEHEAQSNASLD 144 Query: 72 VTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPK---NFSNDIMLLQLERKAKRTRAVQPLR 128 V LG N++E P++R HP Y NF DI LL+LE + P+ Sbjct: 145 VFLGHTNVEELMKLGNH-PIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPIC 203 Query: 129 LPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLR--HYYD--ST 184 LP N G V+G+G K +H L+ V++ V + CE+ LR + D S Sbjct: 204 LPDNDTFYDLGLMGYVSGFGVMEE--KIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQ 261 Query: 185 IELCVGDPEIKKTSFKGDSGG------PLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVH 238 C G P +K+ + +GD+GG P VA GIVS+G TKV ++V Sbjct: 262 NMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVSWGIGCSRGYGFYTKVLNYVD 321 Query: 239 WIKKTMK 245 WIKK M+ Sbjct: 322 WIKKEME 328 >3S9B-A nrPDB Length = 234 Score = 93.2 bits (230), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 66/229 (28%), Positives = 104/229 (45%), Gaps = 10/229 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAH--N 78 ++GG E + P++ L S C G LI ++VLTAAHC +I + LG H N Sbjct: 1 VVGGDECNINEHPFLVALYT-SASSTIHCAGALINREWVLTAAHCDRRNIRIKLGMHSKN 59 Query: 79 IKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKP 138 I+ ++ Q +P + P DIML++L R + + P+ LPS V Sbjct: 60 IRNED-EQIRVPRGKYFCLNTKFPNGLDKDIMLIRLRRPVTYSTHIAPVSLPSRSRGV-- 116 Query: 139 GQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTS 198 G C + GWG+ + + + + + + CE + LC G + + + Sbjct: 117 GSRCRIMGWGKISTT-TYPDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAGILKGGRDT 175 Query: 199 FKGDSGGPLVCNKVAQGIVSYGR---NNGMPPRACTKVSSFVHWIKKTM 244 GDSGGPL+CN GIV+ G + P TKV + +WI+ + Sbjct: 176 CHGDSGGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSII 224 >1SC8-U nrPDB Length = 262 Score = 93.2 bits (230), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 78/251 (31%), Positives = 116/251 (46%), Gaps = 29/251 (11%) Query: 20 EIIGGHEAKPHSRPYMA--YLMIWDQKSLKRCGGFLIRDDFVLTAAHCW-----GSSINV 72 +IIGG ++P+ A Y CGG LI +V++A HC+ V Sbjct: 15 KIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIV 74 Query: 73 TLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFS--NDIMLLQLERKAKR----TRAVQP 126 LG + + V+ I H Y+ + NDI LL++ K R +R +Q Sbjct: 75 YLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQT 134 Query: 127 LRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQE---DRKCESDLRHYYDS 183 + LPS + G +C + G+G+ +++KMTV + R+C+ HYY S Sbjct: 135 ISLPSMYNDPQFGTSCEITGFGKEN--STDYLYPEQLKMTVVKLISHRECQQP--HYYGS 190 Query: 184 TIE---LCVGDPEIKKTSFKGDSGGPLVCN----KVAQGIVSYGRNNGM--PPRACTKVS 234 + LC DP+ K S +GDSGGPLVC+ GIVS+GR + P T+VS Sbjct: 191 EVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVS 250 Query: 235 SFVHWIKKTMK 245 F+ WI+ K Sbjct: 251 HFLPWIRSHTK 261 >6AOD-C nrPDB Length = 245 Score = 93.2 bits (230), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 70/231 (30%), Positives = 102/231 (44%), Gaps = 11/231 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSS-----INVTLG 75 I+GG + P+ L CGG +I + ++LTAAHC+ + V G Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 76 AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ 135 E + F V+ I H Y DI LL+LE + T + +P+ LPS + Sbjct: 61 ILQQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKGDR 120 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIK 195 C V GWG K +TLQ+ K+ + + +C+ R + + +C G E Sbjct: 121 NVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGG 180 Query: 196 KTSFKGDSGGPLVC--NKVAQ--GIVSYGRNNGMPPR--ACTKVSSFVHWI 240 K + KGD+GGPL C N+V GI S+G R T V +V WI Sbjct: 181 KDACKGDAGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWI 231 >2XXL-A nrPDB Length = 408 Score = 92.8 bits (229), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 78/260 (30%), Positives = 120/260 (46%), Gaps = 42/260 (16%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKR--CGGFLIRDDFVLTAAHCWGSSIN----VTL 74 + G+E K SRP+MA L+ + Q R CGG +I + ++LTAAHC N + L Sbjct: 119 VSNGYEVKLSSRPWMA-LLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDLYEIRL 177 Query: 75 GAHNIKEQEPTQQ------------FIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTR 122 G H I +E +Q + +++ + H Y+ ++ +DI LL+L R + Sbjct: 178 GEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNRSVPFQK 237 Query: 123 AVQPLRLPSN---KAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRH 179 ++P+ LP K + + T V GWG T G S L + + +Q C R Sbjct: 238 HIKPICLPITDELKEKAEQISTYFVTGWGTTEN-GSSSDVLLQANVPLQPRSACSQAYRR 296 Query: 180 YYDSTIELCVGDPEIKKTSFKGDSGGPLVC---------------NKVAQGIVSYGRNNG 224 + +LCVG +++ S KGDSGGPL V+QG+V+ G+ + Sbjct: 297 AVPLS-QLCVGGGDLQD-SCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVVTCGQIS- 353 Query: 225 MPPRACTKVSSFVHWIKKTM 244 P T V +V WI TM Sbjct: 354 -LPGLYTNVGEYVQWITDTM 372 >2OLG-A nrPDB Length = 278 Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 73/263 (27%), Positives = 123/263 (46%), Gaps = 34/263 (12%) Query: 15 RADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKR--CGGFLIRDDFVLTAAHCWGSSINV 72 + +A +I+ G + P P+ A + + + ++ CGG LI + +++TAAHC + Sbjct: 17 QVEADKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAHCVAGRVLR 76 Query: 73 TLGAHN-IKEQEPTQQFIP------------------VKRPIPHPAY--NPKNFSNDIML 111 +GA N ++ E P ++ I HP Y K+ +DI L Sbjct: 77 VVGALNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVDGSKDRYHDIAL 136 Query: 112 LQLERKAKRTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDR 171 ++L R+ + T ++P+ LP +V+ GQ +V GWG+T G++S Q++ + V Sbjct: 137 IRLNRQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRTE-TGQYSTIKQKLAVPVVHAE 195 Query: 172 KCESDL--RHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQ-----GIVSYGRNNG 224 +C + +LC G E K S GDSGGPL+ + Q G+VS+G G Sbjct: 196 QCAKTFGAAGVRVRSSQLCAGG-EKAKDSCGGDSGGPLLAERANQQFFLEGLVSFGATCG 254 Query: 225 MP--PRACTKVSSFVHWIKKTMK 245 P TKV + WI+ ++ Sbjct: 255 TEGWPGIYTKVGKYRDWIEGNIR 277 >1A5I-A nrPDB Length = 265 Score = 91.3 bits (225), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 77/254 (30%), Positives = 124/254 (48%), Gaps = 38/254 (14%) Query: 23 GGHEAKPHSRPYMAYLMIWDQKSLKR---CGGFLIRDDFVLTAAHCWGSS-----INVTL 74 GG S P+ A + +++S CGG LI +VLTAAHC+ S + V L Sbjct: 16 GGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVVL 75 Query: 75 G-AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERK----AKRTRAVQPLRL 129 G + +K E Q F VK+ I H ++ ++NDI LLQL+ A+ + +V+ + L Sbjct: 76 GRTYRVKPGEEEQTF-KVKKYIVHKEFDDDTYNNDIALLQLKSDSPQCAQESDSVRAICL 134 Query: 130 PSNKAQVKPGQTCSVAGWGQ---TAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIE 186 P Q+ C ++G+G+ ++P +S L+E + + +C + ++ T+ Sbjct: 135 PEANLQLPDWTECELSGYGKHKSSSPF--YSEQLKEGHVRLYPSSRCAP--KFLFNKTVT 190 Query: 187 ---LCVGD-------PEIKKTSFKGDSGGPLVC----NKVAQGIVSYGRNNGMP--PRAC 230 LC GD P + +GDSGGPLVC + GI+S+G G P Sbjct: 191 NNMLCAGDTRSGEIYPNVHDAC-QGDSGGPLVCMNDNHMTLLGIISWGVGCGEKDVPGVY 249 Query: 231 TKVSSFVHWIKKTM 244 TKV++++ WI+ M Sbjct: 250 TKVTNYLGWIRDNM 263 >1BDA-A nrPDB Length = 265 Score = 90.9 bits (224), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 77/254 (30%), Positives = 124/254 (48%), Gaps = 32/254 (12%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKR---CGGFLIRDDFVLTAAHCWGSS-----INV 72 I GG A S P+ A + ++S CGG LI ++L+AAHC+ + V Sbjct: 14 IKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLTV 73 Query: 73 TLG-AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLE----RKAKRTRAVQPL 127 LG + + E Q+F V++ I H ++ + NDI LLQL+ R A+ + V+ + Sbjct: 74 ILGRTYRVVPGEEEQKF-EVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTV 132 Query: 128 RLPSNKAQVKPGQTCSVAGWGQTAPLGK-HSHTLQEVKMTVQEDRKCESDLRHYYDSTIE 186 LP Q+ C ++G+G+ L +S L+E + + +C S +H + T+ Sbjct: 133 CLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTS--QHLLNRTVT 190 Query: 187 ---LCVGD-----PEIK-KTSFKGDSGGPLVCNKVAQ----GIVSYGRNNGMP--PRACT 231 LC GD P+ + +GDSGGPLVC + GI+S+G G P T Sbjct: 191 DNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYT 250 Query: 232 KVSSFVHWIKKTMK 245 KV++++ WI+ M+ Sbjct: 251 KVTNYLDWIRDNMR 264 >1OP0-A nrPDB Length = 234 Score = 90.5 bits (223), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 71/234 (30%), Positives = 113/234 (48%), Gaps = 20/234 (8%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHN-- 78 +IGG+E + +L+ + + CGG LI ++V+TAAHC + + LG H+ Sbjct: 1 VIGGNECDINEH---RFLVAFFNTTGFFCGGTLINPEWVVTAAHCDSTDFQMQLGVHSKK 57 Query: 79 -IKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVK 137 + E E T+ P ++ I N + DIML++L++ ++ + PL LPS+ V Sbjct: 58 VLNEDEQTRN--PKEKFICPNKNNNEVLDKDIMLIKLDKPISNSKHIAPLSLPSSPPSV- 114 Query: 138 PGQTCSVAGWGQTAPLGKHSHTLQEV----KMTVQEDRKCESDLRHYYDSTIELCVGDPE 193 G C + GWG P+ T +V + + + C++ LC G + Sbjct: 115 -GSVCRIMGWGSITPV---KETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGIVQ 170 Query: 194 IKKTSFKGDSGGPLVCNKVAQGIVSYGRN---NGMPPRACTKVSSFVHWIKKTM 244 K + GDSGGPL+CN QGIVSYG + G P T V + WI++ + Sbjct: 171 GGKDTCGGDSGGPLICNGQFQGIVSYGAHPCGQGPKPGIYTNVFDYTDWIQRNI 224 >3P8G-A nrPDB Length = 241 Score = 90.5 bits (223), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 74/244 (30%), Positives = 114/244 (46%), Gaps = 27/244 (11%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW----------GSSI 70 ++GG +A P+ L Q + CG LI +++++AAHC+ + Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQGHI--CGASLISPNWLVSAAHCYIDDRGFRYSDPTQW 58 Query: 71 NVTLGAHNIKEQE-PTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRL 129 LG H+ ++ P Q +KR I HP +N F DI LL+LE+ A+ + V+P+ L Sbjct: 59 TAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICL 118 Query: 130 PSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCV 189 P G+ V GWG T G + LQ+ ++ V + CE+ L + +CV Sbjct: 119 PDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVIQQTTCENLLPQQITPRM-MCV 177 Query: 190 GDPEIKKTSFKGDSGGPLVC----NKVAQ-GIVSYG-----RNNGMPPRACTKVSSFVHW 239 G S +GDSGGPL ++ Q G+VS+G RN P T++ F W Sbjct: 178 GFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNK---PGVYTRLPLFRDW 234 Query: 240 IKKT 243 IK+ Sbjct: 235 IKEN 238 >3F6U-H nrPDB Length = 240 Score = 90.1 bits (222), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 68/237 (28%), Positives = 109/237 (45%), Gaps = 20/237 (8%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSS--INVTLGAHN 78 +I G + P+ L+ D K CG LI +VLTAAHC S + V LG ++ Sbjct: 1 LIDGKMTRRGDSPWQVVLL--DSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYD 58 Query: 79 IKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLP----SNKA 134 ++ E + + +K HP Y+ NDI LL L + A ++ + P+ LP + + Sbjct: 59 LRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERE 118 Query: 135 QVKPGQTCSVAGWGQTAPLGKH-----SHTLQEVKMTVQEDRKCESDLRHYYDSTIELCV 189 + GQ V GWG + K + L +K+ V +C + + + LC Sbjct: 119 LNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENM-LCA 177 Query: 190 GDPEIKKTSFKGDSGGPLVCN----KVAQGIVSYGRNNGMPPR--ACTKVSSFVHWI 240 G ++ + +GDSGGP+V + G+VS+G G+ TKVS ++ WI Sbjct: 178 GILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWI 234 >1FIW-A nrPDB Length = 290 Score = 90.1 bits (222), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 79/256 (30%), Positives = 121/256 (47%), Gaps = 40/256 (15%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKR---CGGFLIRDDFVLTAAHCWGSSINVT---- 73 IIGG +A + P+M L I+ + +R CGG L+ ++LTAAHC+ VT Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 74 -LGAHNI-----KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPL 127 GA + K +P Q V++ I H Y+ + +NDI L+++ + P Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGPG 120 Query: 128 RLPSNKAQV-KPGQTCSVAGWG-------QTAPLGKHSHTLQEVKMTVQEDRKCESDLRH 179 LP +A + QTC VAGWG +T+P+ LQE ++ + + C S Sbjct: 121 CLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPM------LQEARVDLIDLGLCNST--R 172 Query: 180 YYDSTI---ELCVGDPEIKKTSFKGDSGGPLVCNKVAQ------GIVSYGRNNGMP--PR 228 +Y+ I +C G PE K + +GDSGGPL+C A+ GI S+G P Sbjct: 173 WYNGRIRSTNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGVGCARAKRPG 232 Query: 229 ACTKVSSFVHWIKKTM 244 T S+++WI + Sbjct: 233 VYTSTWSYLNWIASKI 248 >1FIZ-A nrPDB Length = 263 Score = 89.7 bits (221), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 77/246 (31%), Positives = 115/246 (46%), Gaps = 28/246 (11%) Query: 21 IIGGHEAKPHSRPYMAYLMIW---DQKSLKRCGGFLIRDDFVLTAAHCWGSSINVT---- 73 ++GG A+P + P+M L I+ + + CGG L+ +VLTAAHC+ + VT Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 74 -LGAHNI-----KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPL 127 GA+ + K +P Q V+ I H Y NDI L+++ + P Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGPG 120 Query: 128 RLPSNKAQ-VKPGQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTI 185 LP KA + QTC V GWG G + S TLQE ++ + + C S +Y+ I Sbjct: 121 CLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNST--RWYNGRI 178 Query: 186 ---ELCVGDPEIKKTSFKGDSGGPLVCNKVAQ------GIVSYGRNNGMPPRACTKVSS- 235 +C G P K + +GDSGGPL+C A+ GI S+G R S+ Sbjct: 179 RSTNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGVGCARAKRPGVYTSTW 238 Query: 236 -FVHWI 240 +++WI Sbjct: 239 PYLNWI 244 >2HLC-A nrPDB Length = 230 Score = 89.4 bits (220), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 68/230 (29%), Positives = 114/230 (49%), Gaps = 14/230 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKR-CGGFLIRDDFVLTAAHCWGSSINVTLGAHNI 79 II G+EA PY A L I Q + CGG LI + ++LTAAHC +++V + + Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHDAVSVVVYLGSA 60 Query: 80 KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 + E + + +R I H +NP + ND+ L+++ + T +QP+RLPS + Sbjct: 61 VQYE-GEAVVNSERIISHSMFNPDTYLNDVALIKIPH-VEYTDNIQPIRLPSGEELNNKF 118 Query: 140 QT--CSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKT 197 + +V+GWGQ+ + LQ V ++ +C + +C GD K+ Sbjct: 119 ENIWATVSGWGQS---NTDTVILQYTYNLVIDNDRCAQEYPPGIIVESTIC-GDTSDGKS 174 Query: 198 SFKGDSGGPLVCN--KVAQGIVSYGRNNGMP---PRACTKVSSFVHWIKK 242 GDSGGP V + + G+VS+ G P ++V+S++ WI++ Sbjct: 175 PCFGDSGGPFVLSDKNLLIGVVSFVSGAGCESGKPVGFSRVTSYMDWIQQ 224 >2ASU-B nrPDB Length = 234 Score = 88.6 bits (218), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 71/246 (28%), Positives = 113/246 (45%), Gaps = 41/246 (16%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGS------SINVTL 74 ++GGH P + P+ L +++ CGG L+++ ++LTA C+ S V L Sbjct: 1 VVGGH---PGNSPWTVSLR--NRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWL 55 Query: 75 GA--HNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSN 132 G N + EP+ Q +PV + + P+ + ++LL+LER + V + LP Sbjct: 56 GTLFQNPQHGEPSLQRVPVAKMVCGPS------GSQLVLLKLERSVTLNQRVALICLPPE 109 Query: 133 KAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDP 192 V PG C +AGWG+T G + L + V +++C R + E+C Sbjct: 110 WYVVPPGTKCEIAGWGETKGTGNDT-VLNVALLNVISNQECNIKHRGRVRES-EMCTEGL 167 Query: 193 EIKKTSFKGDSGGPLVC----NKVAQGIVSYGRNNGMPPRAC---------TKVSSFVHW 239 + +GD GGPL C + V +GI+ +P R C T+VS FV W Sbjct: 168 LAPVGACEGDYGGPLACFTHNSWVLEGII-------IPNRVCARSRWPAVFTRVSVFVDW 220 Query: 240 IKKTMK 245 I K M+ Sbjct: 221 IHKVMR 226 >2OQ5-A nrPDB Length = 232 Score = 88.6 bits (218), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 71/238 (29%), Positives = 109/238 (45%), Gaps = 30/238 (12%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC---------WGSSIN 71 I+GG E + P+ A L WD RCG LI ++++AAHC W +S Sbjct: 1 IVGGTEVEEGEWPWQASLQ-WDGS--HRCGATLINATWLVSAAHCFTTYKNPARWTASFG 57 Query: 72 VTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPS 131 VT+ +P++ ++R I H Y + DI L +L T AV + LP Sbjct: 58 VTI--------KPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPD 109 Query: 132 NKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIE--LCV 189 + +PG V G+G G + L++ ++T+ + C ++ + Y D+ LC Sbjct: 110 ASYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTC-NEPQAYNDAITPRMLCA 168 Query: 190 GDPEIKKTSFKGDSGGPLVCNKVAQ-----GIVSYGRNNGMP--PRACTKVSSFVHWI 240 G E K + +GDSGGPLV + GIVS+G P P T+V++ WI Sbjct: 169 GSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWI 226 >5KWM-A nrPDB Length = 230 Score = 88.2 bits (217), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 64/213 (30%), Positives = 93/213 (43%), Gaps = 14/213 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSS----INVTLGA 76 I+GG +A P+ L+ D + CGG L + V+TAAHC S INV G Sbjct: 1 IVGGEDANVQDHPFTVALVTPDGQQF--CGGTLAAPNKVVTAAHCTVGSQPADINVVSGR 58 Query: 77 HNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLP-SNKAQ 135 + E T V HP Y D+ +L LE K P+ L ++ A Sbjct: 59 TVMSSNEGT--VSKVTNVWVHPEYQDAAKGFDVSVLTLEAPVKEA----PIELAKADDAG 112 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIK 195 P ++ GWG T+ G+ + LQ+ + V D C+ Y + +C G PE Sbjct: 113 YAPDTAATILGWGNTSEGGQQADHLQKATVPVNSDDTCKQAYGEYTPDAM-VCAGVPEGG 171 Query: 196 KTSFKGDSGGPLVCNKVAQGIVSYGRNNGMPPR 228 + +GDSGGP+V N G+ S+G P + Sbjct: 172 VDTCQGDSGGPMVVNNKLIGVTSWGEGCARPGK 204 >1FON-A nrPDB Length = 240 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 68/240 (28%), Positives = 108/240 (45%), Gaps = 23/240 (9%) Query: 24 GHEAKPHSRPYMAYLMIWDQKSLKR-CGGFLIRDDFVLTAAHCWGSS--INVTLGAHNIK 80 G +A P+S + L + CGG LI D+V+TA HC +S V LG ++ Sbjct: 2 GEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSRTYQVVLGEYDRS 61 Query: 81 EQEPTQQFIPVKRP--IPHPAYNPKNFS--NDIMLLQLERKAKRTRAVQPLRLPSNKAQV 136 E ++Q IP+ HP +N + NDI L++L R A+ VQ LP + Sbjct: 62 VLEGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPAGDIL 121 Query: 137 KPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIE---LCVGDPE 193 C ++GWG+ G LQ+ + + C ++ T++ +C G Sbjct: 122 PNEAPCYISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQ--WDWWGITVKKTMVCAGGD- 178 Query: 194 IKKTSFKGDSGGPLVC---------NKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTM 244 ++ GDSGGPL C + V + ++G N P T+VS+F+ WI +T+ Sbjct: 179 -TRSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWIDETI 237 >1KIG-H nrPDB Length = 241 Score = 87.4 bits (215), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 68/237 (28%), Positives = 116/237 (48%), Gaps = 16/237 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW--GSSINVTLGAHN 78 I+GG + P+ A L+ ++++ CGG ++ + +VLTAAHC V +G N Sbjct: 1 IVGGRDCAEGECPWQALLV--NEENEGFCGGTILNEFYVLTAAHCLHQAKRFTVRVGDRN 58 Query: 79 IKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSN---KAQ 135 +++E + V+ + H + + + DI +L+L+ + R V P LP +A Sbjct: 59 TEQEEGNEMAHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAEAT 118 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIEL-CVGDPEI 194 + +T V+G+G+T G+ S TL+ +++ + C+ L + T + C G Sbjct: 119 LMTQKTGIVSGFGRTHEKGRLSSTLKMLEVPYVDRSTCK--LSSSFTITPNMFCAGYDTQ 176 Query: 195 KKTSFKGDSGGPLVC----NKVAQGIVSYGRNNGMPPR--ACTKVSSFVHWIKKTMK 245 + + +GDSGGP V GIVS+G + TKVS+F+ WI K MK Sbjct: 177 PEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKFGVYTKVSNFLKWIDKIMK 233 >5LPF-A nrPDB Length = 234 Score = 87.0 bits (214), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 64/212 (30%), Positives = 103/212 (48%), Gaps = 23/212 (10%) Query: 49 CGGFLIRDDFVLTAAHCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNP------ 102 C G L+ +VLTAAHC + +G ++ + +Q R + HP Y+ Sbjct: 29 CAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQ-GEQLRRTTRSVVHPKYHQGSGPIL 87 Query: 103 --KNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLG-KHSHT 159 + +D+MLL+L R V+ L+LP AQ PG C VAGWG TA K++ Sbjct: 88 PRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQ--PGDQCQVAGWGTTAARRVKYNKG 145 Query: 160 LQEVKMTVQEDRKCESDLRHYYDSTIE---LCVGDPEIKKTSFKGDSGGPLVCNKVAQGI 216 L +T+ ++CE +Y + +C G + + + DSGGPLVC++ QGI Sbjct: 146 LTCSSITILSPKECEV----FYPGVVTNNMICAG-LDRGQDPCQSDSGGPLVCDETLQGI 200 Query: 217 VSYGR---NNGMPPRACTKVSSFVHWIKKTMK 245 +S+G + P T++ ++ WI K ++ Sbjct: 201 LSWGVYPCGSAQHPAVYTQICKYMSWINKVIR 232 >4IGD-A nrPDB Length = 406 Score = 85.1 bits (209), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 69/258 (26%), Positives = 111/258 (43%), Gaps = 33/258 (12%) Query: 15 RADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSIN--- 71 R +I G A+ + P++A L + + CGG L+ +++TAAHC S++ Sbjct: 150 RKLMAQIFNGRPAQKGTTPWIAMLSHLNGQPF--CGGSLLGSSWIVTAAHCLHQSLDPED 207 Query: 72 ---------------VTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLER 116 + LG H + +Q + VK HP Y+P F ND+ L++L Sbjct: 208 PTLRDSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLE 267 Query: 117 KAKRTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESD 176 V P+ LP Q G V+GWG+ L + TL E+++ + + C+ Sbjct: 268 SPVLNAFVMPICLPEGPQQ--EGAMVIVSGWGKQF-LQRFPETLMEIEIPIVDHSTCQKA 324 Query: 177 LRHYYDSTIE--LCVGDPEIKKTSFKGDSGGPLVCNKVAQ------GIVSYGRNNGMPPR 228 +C G+ E K + GDSGGP+V + G VS+G + G R Sbjct: 325 YAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKKDR 384 Query: 229 ACTKVSSFVHWIKKTMKR 246 V S++H K ++R Sbjct: 385 Y--GVYSYIHHNKDWIQR 400 >1C5M-D nrPDB Length = 255 Score = 85.1 bits (209), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 63/236 (26%), Positives = 113/236 (47%), Gaps = 14/236 (5%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW--GSSINVTLGAHN 78 I+GG E K P+ A L+ ++++ CGG ++ + ++LTAAHC V +G N Sbjct: 1 IVGGQECKDGECPWQALLI--NEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRN 58 Query: 79 IKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSN---KAQ 135 +++E + V+ I H + + + DI +L+L+ V P LP ++ Sbjct: 59 TEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAEST 118 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIK 195 + +T V+G+G+T G+ S L+ +++ + C+ + C G + Sbjct: 119 LMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNM-FCAGYDTKQ 177 Query: 196 KTSFKGDSGGPLVC----NKVAQGIVSYGRNNGMPPR--ACTKVSSFVHWIKKTMK 245 + + +GDSGGP V GIVS+G + TKV++F+ WI ++MK Sbjct: 178 EDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMK 233 >4DJZ-B nrPDB Length = 251 Score = 84.3 bits (207), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 68/252 (26%), Positives = 109/252 (43%), Gaps = 33/252 (13%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSIN--------- 71 I G A+ + P++A L + + CGG L+ +++TAAHC S++ Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLNGQPF--CGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDS 58 Query: 72 ---------VTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTR 122 + LG H + +Q + VK HP Y+P F ND+ L++L Sbjct: 59 DLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLNA 118 Query: 123 AVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYD 182 V P+ LP Q G V+GWG+ L + TL E+++ + + C+ Sbjct: 119 FVMPICLPEGPQQ--EGAMVIVSGWGKQF-LQRFPETLMEIEIPIVDHSTCQKAYAPLKK 175 Query: 183 STIE--LCVGDPEIKKTSFKGDSGGPLVCNKVAQ------GIVSYGRNNGMPPRACTKVS 234 +C G+ E K + GDSGGP+V + G VS+G + G R V Sbjct: 176 KVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKKDR--YGVY 233 Query: 235 SFVHWIKKTMKR 246 S++H K ++R Sbjct: 234 SYIHHNKDWIQR 245 >5O32-I nrPDB Length = 244 Score = 84.3 bits (207), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 74/245 (30%), Positives = 111/245 (45%), Gaps = 28/245 (11%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSIN--VTLGAHN 78 I+GG A+ P+ + S CGG I ++LTAAHC +S + Sbjct: 1 IVGGKRAQLGDLPWQVAI---KDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTV 57 Query: 79 IKEQEPTQQFIP---VKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPS---- 131 + P + I V R I H YN + NDI L+++++ + P +P+ Sbjct: 58 VDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPW 117 Query: 132 NKAQVKPGQTCSVAGWGQTAPLGKHSHTLQ--EVKMTVQEDRKCESDL-RHYYDSTIELC 188 + +P TC V+GWG+ + +LQ EVK+ C +Y+ +E C Sbjct: 118 SPYLFQPNDTCIVSGWGREKD-NERVFSLQWGEVKLI----SNCSKFYGNRFYEKEME-C 171 Query: 189 VGDPEIKKTSFKGDSGGPLVC---NKV--AQGIVSYGRNNGMP--PRACTKVSSFVHWIK 241 G + + KGDSGGPLVC N V G+VS+G N G P P TKV+++ WI Sbjct: 172 AGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWIS 231 Query: 242 KTMKR 246 + R Sbjct: 232 YHVGR 236 >1BQY-A nrPDB Length = 234 Score = 84.3 bits (207), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 67/229 (29%), Positives = 104/229 (45%), Gaps = 10/229 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 + GG E + + L + CGG LI D+V+TAAHC ++ + G H+ K Sbjct: 1 VFGGDECNINEHRSLVVLF---NSNGFLCGGTLINQDWVVTAAHCDSNNFQLLFGVHSKK 57 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKN-FSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 +Q K P + DIML++L+ + + PL LPS+ V G Sbjct: 58 ILNEDEQTRDPKEKFFCPNRKKDDEVDKDIMLIKLDSSVSNSEHIAPLSLPSSPPSV--G 115 Query: 140 QTCSVAGWGQTAPLGK-HSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTS 198 C + GWG+T P + + + + + C + + LC G + + + Sbjct: 116 SVCRIMGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGILQGGRDT 175 Query: 199 FKGDSGGPLVCNKVAQGIVSYGRN-NGMP--PRACTKVSSFVHWIKKTM 244 DSGGPL+CN + QGIVS+G + G P P TKV ++ WIK + Sbjct: 176 CHFDSGGPLICNGIFQGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSII 224 >1SI5-H nrPDB Length = 240 Score = 83.6 bits (205), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 62/230 (26%), Positives = 109/230 (47%), Gaps = 20/230 (8%) Query: 31 SRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGS----SINVTLGAHNI--KEQEP 84 +R + +++ ++ CGG LI++ +VLTA C+ S LG H++ + E Sbjct: 7 TRTNIGWMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHDVHGRGDEK 66 Query: 85 TQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQTCSV 144 +Q + V + + Y P+ +D++L++L R A V + LP+ + + +CSV Sbjct: 67 CKQVLNVSQLV----YGPE--GSDLVLMKLARPAVLDDFVSTIDLPNYGSTIPEKTSCSV 120 Query: 145 AGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYD-STIELCVGDPEIKKTSFKGDS 203 GWG T L + L+ + + + KC R + E+C G +I +GD Sbjct: 121 YGWGYTG-LINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPCEGDY 179 Query: 204 GGPLVCN----KVAQGIVSYGRNNGMP--PRACTKVSSFVHWIKKTMKRY 247 GGPLVC ++ G++ GR +P P +V+ + WI K + Y Sbjct: 180 GGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKIILTY 229 >2XRC-A nrPDB Length = 565 Score = 83.2 bits (204), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 79/264 (29%), Positives = 118/264 (44%), Gaps = 38/264 (14%) Query: 12 LLPRADAG----------EIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLT 61 LLP+ G I+GG A+ P+ + I D + CGG I ++LT Sbjct: 303 LLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQ--VAIKDASGIT-CGGIYIGGCWILT 359 Query: 62 AAHCWGSSIN--VTLGAHNIKEQEPTQQFIP---VKRPIPHPAYNPKNFSNDIMLLQLER 116 AAHC +S + + P + I V R I H YN + NDI L+++++ Sbjct: 360 AAHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKK 419 Query: 117 KAKRTRAVQPLRLPS----NKAQVKPGQTCSVAGWGQTAPLGKHSHTLQ--EVKMTVQED 170 + P +P+ + +P TC V+GWG+ + +LQ EVK+ Sbjct: 420 DGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKD-NERVFSLQWGEVKLI---- 474 Query: 171 RKCESDL-RHYYDSTIELCVGDPEIKKTSFKGDSGGPLVC---NKVAQ--GIVSYGRNNG 224 C +Y+ +E C G + + KGDSGGPLVC N V G+VS+G N G Sbjct: 475 SNCSKFYGNRFYEKEME-CAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCG 533 Query: 225 MP--PRACTKVSSFVHWIKKTMKR 246 P P TKV+++ WI + R Sbjct: 534 KPEFPGVYTKVANYFDWISYHVGR 557 >2B9L-A nrPDB Length = 394 Score = 82.0 bits (201), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 67/224 (29%), Positives = 106/224 (47%), Gaps = 31/224 (13%) Query: 49 CGGFLIRDDFVLTAAHCWGS------SINVTLGAHNI---KEQEPTQQFIPVKRPIPHPA 99 CGG LI VLT AHC S +I + G + KE+ P Q+ +++ I H Sbjct: 164 CGGSLIAPSVVLTGAHCVNSYQSNLDAIKIRAGEWDTLTEKERLPYQER-KIRQVIIHSN 222 Query: 100 YNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKH--S 157 +NPK ND+ LL L+R + + + LP ++Q+ C +GWG+ +H S Sbjct: 223 FNPKTVVNDVALLLLDRPLVQADNIGTICLPQ-QSQIFDSTECFASGWGKKEFGSRHRYS 281 Query: 158 HTLQEVKMTVQEDRKCESDLRH-------YYDSTIELCVGDPEIKKTSFKGDSGGPLVC- 209 + L+++++ + KC++DLR+ D T +C G + K T GD G PL C Sbjct: 282 NILKKIQLPTVDRDKCQADLRNTRLGLKFVLDQTF-VCAGGEQGKDTC-TGDGGSPLFCP 339 Query: 210 ------NKVAQGIVSYGRNNGMP--PRACTKVSSFVHWIKKTMK 245 + GIV++G G P V+ F +WI + M+ Sbjct: 340 DPRNPSRYMQMGIVAWGIGCGDENVPGVYANVAHFRNWIDQEMQ 383 >4Z6A-H nrPDB Length = 249 Score = 81.6 bits (200), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 71/242 (29%), Positives = 109/242 (45%), Gaps = 24/242 (9%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC------WGSSINVTL 74 I+GG P+ L++ + CGG LI +V++AAHC W + I V L Sbjct: 1 IVGGKVCPKGECPWQVLLLV---NGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAV-L 56 Query: 75 GAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPS--- 131 G H++ E + +Q V + I Y P ++DI LL+L + T V PL LP Sbjct: 57 GEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTF 116 Query: 132 NKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIE--LCV 189 ++ + + V+GWGQ G + L + + + CE+ Y E C Sbjct: 117 SERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEAS---YPGKITEYMFCA 173 Query: 190 GDPEIKKTSFKGDSGGPLVCNK----VAQGIVSYGRNNGMPPR--ACTKVSSFVHWIKKT 243 G + K S KGDSGGP + GIVS+G+ T+VS ++ W++K Sbjct: 174 GYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKL 233 Query: 244 MK 245 M+ Sbjct: 234 MR 235 >2PKA-B nrPDB Length = 152 Score = 81.3 bits (199), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 51/150 (34%), Positives = 81/150 (54%), Gaps = 9/150 (6%) Query: 103 KNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAP---LGKHSHT 159 K++S+D+MLL+L+ AK T AV+ L LP+ + ++ G TC +GWG P + Sbjct: 4 KDYSHDLMLLRLQSPAKITDAVKVLELPTQEPEL--GSTCEASGWGSIEPGPDDFEFPDE 61 Query: 160 LQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSY 219 +Q V++T+ ++ C +D + LC G K + GDSGGPL+CN + QGI S+ Sbjct: 62 IQCVQLTLLQNTFC-ADAHPDKVTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQGITSW 120 Query: 220 GRN---NGMPPRACTKVSSFVHWIKKTMKR 246 G + P TK+ ++ WI T+ Sbjct: 121 GHTPCGSANKPSIYTKLIFYLDWIDDTITE 150 >4IW4-E nrPDB Length = 279 Score = 79.0 bits (193), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 77/272 (28%), Positives = 115/272 (42%), Gaps = 54/272 (19%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKR----CGGFLIRDDFVLTAAHCWGSS------- 69 IIGG A+P P+ A +++ D + G L+ ++LTAAH S Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 70 ------INVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRA 123 + V LG H+++++ R + HP +N +N+++DI L+QL+ Sbjct: 61 PVSKEHVTVYLGLHDVRDKSGAVNS-SAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPH 119 Query: 124 VQPLRLPSNKAQV-KPGQTCSVAGWGQTAP-----------LGKHSHTLQEVKMTVQEDR 171 V P+ LP + + P VAGWG + P S LQ VK+ V Sbjct: 120 VMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHA 179 Query: 172 KC----ESDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNK------VAQGIVSYGR 221 +C ES +Y + C G E K + GDSGG V V QG+VS+G Sbjct: 180 ECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWGG 239 Query: 222 NNGMPPRAC---------TKVSSFVHWIKKTM 244 P C TKVS++V W+ + M Sbjct: 240 -----PEECGSKQVYGVYTKVSNYVDWVWEQM 266 >4LK4-A nrPDB Length = 357 Score = 78.6 bits (192), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 68/243 (27%), Positives = 112/243 (46%), Gaps = 25/243 (10%) Query: 18 AGEIIGGHEAKPHSRPYMAYLMI--WDQKSLKRCGGFLIRDDFVLTAAHCWGS----SIN 71 + II G A P + L+ D + CGG + +VLTAAHC+ S S++ Sbjct: 8 SSRIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRSAASVD 67 Query: 72 VTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRL-- 129 V +GA+++ ++ I ++ H +Y+P N NDI +++L +T ++ + L Sbjct: 68 VIIGAYDLNNSSQGER-IAAQKIYRHLSYSPSNLLNDIAIVEL----AQTSSLPAITLAG 122 Query: 130 PSNKAQVKPGQTCSVAGWGQTAPLG--KHSHTLQEVKMTVQEDRKCESDLRHYYDS---T 184 P+ + + +VAGWG T + + LQEV + + C+ ++H S + Sbjct: 123 PATRTSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQHGISSDPNS 182 Query: 185 IELCVGDPEIKKTSFKGDSGGPLVCNKVAQ--GIVSYGRNNGMPPRA---CTKVSSFVHW 239 C + K S +GD+GGP+V + GIVS+G T VS F W Sbjct: 183 TNFCAA--RLTKDSCQGDAGGPIVVKTGREQLGIVSWGDEQCAKTGTYGVYTNVSYFRDW 240 Query: 240 IKK 242 I K Sbjct: 241 ITK 243 >3VGC-B nrPDB Length = 131 Score = 77.8 bits (190), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 43/131 (32%), Positives = 64/131 (48%), Gaps = 3/131 (2%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTL-GAHNI 79 I+ G EA P S P+ L D+ CGG LI +++V+TAAHC ++ +V + G + Sbjct: 1 IVNGEEAVPGSWPWQVSLQ--DKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQ 58 Query: 80 KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 Q + + + + YN +NDI LL+L A ++ V + LPS G Sbjct: 59 GSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAAG 118 Query: 140 QTCSVAGWGQT 150 TC GWG T Sbjct: 119 TTCVTTGWGLT 129 >2JET-B nrPDB Length = 128 Score = 76.6 bits (187), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 42/128 (32%), Positives = 64/128 (50%), Gaps = 3/128 (2%) Query: 24 GHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTL-GAHNIKEQ 82 G +A P S P+ L D+ CGG LI +D+V+TAAHC + +V + G + Sbjct: 1 GEDAIPGSWPWQVSLQ--DKTGFHFCGGSLISEDWVVTAAHCGVKTSDVVVAGEFDQGSD 58 Query: 83 EPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQTC 142 E Q + + + +P +N NDI LL+L A+ + V + LP+ PG C Sbjct: 59 EENIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDFPPGTVC 118 Query: 143 SVAGWGQT 150 + GWG+T Sbjct: 119 ATTGWGKT 126 >3I77-A nrPDB Length = 230 Score = 76.3 bits (186), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 62/239 (25%), Positives = 99/239 (41%), Gaps = 25/239 (10%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW---GSSINVTLGAH 77 ++GG A P+M L+ ++++ CGG L D VLTAAHC G++ ++T Sbjct: 1 VVGGTRAAQGEFPFMVRLI--NEENEGFCGGALYAQDIVLTAAHCVSGSGNNTSITATGG 58 Query: 78 NIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVK 137 + Q + + + + P + + + D L++L QP+ P+ K Sbjct: 59 VVDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKL---------AQPINQPTLKIATT 109 Query: 138 PG---QTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEI 194 T +VAGWG G L + + D C S + +C G P+ Sbjct: 110 TAYNQGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYPDT 169 Query: 195 KKT-SFKGDSGGPLVCNKVAQ-----GIVSYGRNNGMP--PRACTKVSSFVHWIKKTMK 245 + +GDSGGP+ A GIVS+G P P T+VS+F I + Sbjct: 170 GGVDTCQGDSGGPMFRKDNADEWIQVGIVSWGYGCARPGYPGVYTEVSTFASAIASAAR 228 >5XRF-A nrPDB Length = 242 Score = 75.1 bits (183), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 63/232 (27%), Positives = 107/232 (46%), Gaps = 14/232 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 +IGG+E + ++A + +C G LI +++VL AAHC+ +N+ LG HN Sbjct: 7 VIGGNECDTNEHRFLAAFFT-SRPWTFQCAGTLIHEEWVLAAAHCYKRGLNIYLGMHNQS 65 Query: 81 EQ-EPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 Q + Q+ ++ + D++LL+L + + + PL LPS+ + G Sbjct: 66 IQFDDEQRRYAIEEHYYRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPLSLPSSPPSI--G 123 Query: 140 QTCSVAGWGQTAPLGKHSHTLQEV----KMTVQEDRKCESDLRHYYDSTIELCVGDPEIK 195 C V GWG + L +V + + +C + ++T LC G E Sbjct: 124 SVCRVMGWG---IMSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLCAGVLEGG 180 Query: 196 KTSFKGDSGGPLVCNKVAQGIVSYGRNNGMPPRA---CTKVSSFVHWIKKTM 244 + DSGGPL+C+ QGIV +G+ P T+VS++ WI+ + Sbjct: 181 IDTCNQDSGGPLICDGQFQGIVFFGKYPCAQPNKPGLYTRVSNYNDWIQNII 232 >4KKD-A nrPDB Length = 433 Score = 75.1 bits (183), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 76/272 (27%), Positives = 114/272 (41%), Gaps = 54/272 (19%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKR----CGGFLIRDDFVLTAAHCWGSS------- 69 IIGG A+P P+ A +++ D + G L+ ++LTAAH S Sbjct: 155 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 214 Query: 70 ------INVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRA 123 + V LG H+++++ R + HP +N +N+++DI L+QL+ Sbjct: 215 PVSKEHVTVYLGLHDVRDKSGAVNS-SAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPH 273 Query: 124 VQPLRLPSNKAQ-VKPGQTCSVAGWGQTAP-----------LGKHSHTLQEVKMTVQEDR 171 V P+ LP + + P VAGWG + P S LQ VK+ V Sbjct: 274 VMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHA 333 Query: 172 KC----ESDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNK------VAQGIVSYGR 221 +C ES +Y + C G E K + GDSG V V QG+VS+G Sbjct: 334 ECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGEAFVIFDDLSQRWVVQGLVSWGG 393 Query: 222 NNGMPPRAC---------TKVSSFVHWIKKTM 244 P C TKVS++V W+ + M Sbjct: 394 -----PEECGSKQVYGVYTKVSNYVDWVWEQM 420 >3H7O-A nrPDB Length = 228 Score = 71.6 bits (174), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 60/231 (25%), Positives = 97/231 (41%), Gaps = 12/231 (5%) Query: 23 GGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGS----SINVTLGAHN 78 GG + P+ + + + CGG ++ FVLTAAHC +I + + N Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTN 61 Query: 79 IKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAK-RTRAVQPLRLPSNKAQVK 137 + E P + Y + NDI +L+L R K +P +LP + + K Sbjct: 62 LWEDPGKSD--PYVSHVYLSFYRQETMENDIAILELSRPLKLDGLKSKPAKLPDIEFRPK 119 Query: 138 PGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKT 197 G V+G+G + H L+ ++TV + +C + + S C + Sbjct: 120 TGSDVLVSGYGDGQTMDPKDHDLKSAQLTVVDLDECRTKYGPIFLSLQVFCAQKVGVSLE 179 Query: 198 SFKGDSGGPLVCNKVAQGIVSY--GRNNGMPPRACTKVSSFVHWIKKTMKR 246 S GD+G P V G+ +Y R G P TKV S+V WI+ +K+ Sbjct: 180 S--GDAGDPTVQQDTLVGVAAYFPKRPEGA-PEVFTKVGSYVSWIQDIIKK 227 >1ZJK-A nrPDB Length = 403 Score = 71.6 bits (174), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 69/259 (26%), Positives = 111/259 (42%), Gaps = 31/259 (11%) Query: 12 LLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW----- 66 L R G+I GG +AKP P+ ++ G L+ D++VLTAAH Sbjct: 153 LSARTTGGQIYGGQKAKPGDFPWQVLIL-----GGTTAAGALLYDNWVLTAAHAVYEQKH 207 Query: 67 -GSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAY-NPKNFSNDIMLLQLERKAKRTRAV 124 S++++ +G +K P + H Y + F NDI L++L K + Sbjct: 208 DASALDIRMG--TLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNI 265 Query: 125 QPLRLPSNKAQ--VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRH--Y 180 P+ LP +A+ ++ + +GWG T G + L V + + + +KC + Y Sbjct: 266 TPICLPRKEAESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQKCTAAYEKPPY 324 Query: 181 YDSTIE---LCVGDPEIKKTSFKGDSGGPLVC------NKVAQGIVSYGRNN---GMPPR 228 ++ LC G K S +GDSGG LV GIVS+G N Sbjct: 325 PRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYG 384 Query: 229 ACTKVSSFVHWIKKTMKRY 247 TKV +++ WI+ + + Sbjct: 385 VYTKVINYIPWIENIISDF 403 >3NXP-A nrPDB Length = 424 Score = 70.9 bits (172), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 77/268 (28%), Positives = 114/268 (42%), Gaps = 34/268 (12%) Query: 12 LLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-----W 66 LL G I+ G +A+ P+ L + L CG LI D +VLTAAHC W Sbjct: 157 LLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPW 215 Query: 67 GSSIN-----VTLGAHNIKEQEPTQQFIPVKRPI-PHPAYNPK-NFSNDIMLLQLERKAK 119 + V +G H+ E + I + I HP YN + N DI L++L++ Sbjct: 216 DKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVA 275 Query: 120 RTRAVQPLRLPSNKAQ---VKPGQTCSVAGWGQ-----TAPLGK-HSHTLQEVKMTVQED 170 + + P+ LP + ++ G V GWG TA +GK LQ V + + E Sbjct: 276 FSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVER 335 Query: 171 RKCESDLRHYYDSTIELCVG---DPEIKKTSFKGDSGGPLVC-----NKVAQ-GIVSYGR 221 C+ R + C G D + + +GDSGGP V N+ Q GIVS+G Sbjct: 336 PVCKDSTRIRITDNM-FCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE 394 Query: 222 NNGMPPRA--CTKVSSFVHWIKKTMKRY 247 + T V WI+K + ++ Sbjct: 395 GCDRDGKYGFYTHVFRLKKWIQKVIDQF 422 >1Q3X-A nrPDB Length = 328 Score = 70.9 bits (172), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 69/259 (26%), Positives = 110/259 (42%), Gaps = 31/259 (11%) Query: 12 LLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW----- 66 L R G I GG +AKP P+ ++ G L+ D++VLTAAH Sbjct: 78 LSARTTGGRIYGGQKAKPGDFPWQVLIL-----GGTTAAGALLYDNWVLTAAHAVYEQKH 132 Query: 67 -GSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAY-NPKNFSNDIMLLQLERKAKRTRAV 124 S++++ +G +K P + H Y + F NDI L++L K + Sbjct: 133 DASALDIRMG--TLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNI 190 Query: 125 QPLRLPSNKAQ--VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRH--Y 180 P+ LP +A+ ++ + +GWG T G + L V + + + +KC + Y Sbjct: 191 TPICLPRKEAESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQKCTAAYEKPPY 249 Query: 181 YDSTIE---LCVGDPEIKKTSFKGDSGGPLVC------NKVAQGIVSYGRNN---GMPPR 228 ++ LC G K S +GDSGG LV GIVS+G N Sbjct: 250 PRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYG 309 Query: 229 ACTKVSSFVHWIKKTMKRY 247 TKV +++ WI+ + + Sbjct: 310 VYTKVINYIPWIENIISDF 328 >3K65-B nrPDB Length = 308 Score = 70.9 bits (172), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 76/268 (28%), Positives = 114/268 (42%), Gaps = 34/268 (12%) Query: 12 LLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-----W 66 LL G I+ G +A+ P+ L + L CG LI D +VLTAAHC W Sbjct: 41 LLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPW 99 Query: 67 GSSIN-----VTLGAHNIKEQEPTQQFIPVKRPI-PHPAYNPK-NFSNDIMLLQLERKAK 119 + V +G H+ E + I + I HP YN + N DI L++L++ Sbjct: 100 DKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVA 159 Query: 120 RTRAVQPLRLPSNKAQ---VKPGQTCSVAGWGQ-----TAPLGK-HSHTLQEVKMTVQED 170 + + P+ LP + ++ G V GWG TA +GK LQ V + + E Sbjct: 160 FSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVER 219 Query: 171 RKCESDLRHYYDSTIELCVG---DPEIKKTSFKGDSGGPLVC-----NKVAQ-GIVSYGR 221 C+ R + C G D + + +GD+GGP V N+ Q GIVS+G Sbjct: 220 PVCKDSTRIRITDNM-FCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIVSWGE 278 Query: 222 NNGMPPRA--CTKVSSFVHWIKKTMKRY 247 + T V WI+K + ++ Sbjct: 279 GCDRDGKYGFYTHVFRLKKWIQKVIDQF 306 >1M9U-A nrPDB Length = 241 Score = 70.5 bits (171), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 66/240 (27%), Positives = 96/240 (40%), Gaps = 19/240 (7%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG----SSINVTLGA 76 +IGG A P P+ CG L+ L+A+HC ++I V G Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAGL 60 Query: 77 HNIKEQEPTQQFIPVKRPIPHPAYNP--KNFSNDIMLLQLERKAKRTRAVQPLRLPSNKA 134 + TQ V H Y ++SNDI +L L +Q LP+N Sbjct: 61 WQQSDTSGTQT-ANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANNN 119 Query: 135 QVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTI---ELCVGD 191 G TC ++GWG+T LQ+ + V +C + + + I +CV D Sbjct: 120 NDYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVGGANIWDNHICVQD 179 Query: 192 PEIKKTSFKGDSGGPLVCNK-------VAQGIVSYGRNNGMP--PRACTKVSSFVHWIKK 242 P + GDSGGPL C V +VS G +P P T+VS+++ WI Sbjct: 180 PAGNTGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGACLPDYPSVYTRVSAYLGWIGD 239 >4NZQ-A nrPDB Length = 557 Score = 70.1 bits (170), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 77/268 (28%), Positives = 114/268 (42%), Gaps = 34/268 (12%) Query: 12 LLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-----W 66 LL G I+ G +A+ P+ L + L CG LI D +VLTAAHC W Sbjct: 290 LLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPW 348 Query: 67 GSSIN-----VTLGAHNIKEQEPTQQFIPVKRPIP-HPAYNPK-NFSNDIMLLQLERKAK 119 + V +G H+ E + I + I HP YN + N DI L++L++ Sbjct: 349 DKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVA 408 Query: 120 RTRAVQPLRLPSNKAQ---VKPGQTCSVAGWGQ-----TAPLGK-HSHTLQEVKMTVQED 170 + + P+ LP + ++ G V GWG TA +GK LQ V + + E Sbjct: 409 FSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVER 468 Query: 171 RKCESDLRHYYDSTIELCVG---DPEIKKTSFKGDSGGPLVC-----NKVAQ-GIVSYGR 221 C+ R + C G D + + +GDSGGP V N+ Q GIVS+G Sbjct: 469 PVCKDSTRIRITDNM-FCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE 527 Query: 222 NNGMPPRA--CTKVSSFVHWIKKTMKRY 247 + T V WI+K + ++ Sbjct: 528 GCDRDGKYGFYTHVFRLKKWIQKVIDQF 555 >1PQ7-A nrPDB Length = 224 Score = 70.1 bits (170), Expect = 9e-13, Method: Compositional matrix adjust. Identities = 57/212 (26%), Positives = 90/212 (42%), Gaps = 14/212 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG----SSINVTLGA 76 I+GG A P++ + + CGG L+ + VLTAAHC S + G+ Sbjct: 1 IVGGTSASAGDFPFIVSI---SRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQIRAGS 57 Query: 77 HNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQV 136 + T V+ HP+Y+ N ND+ +L+L + RL ++ + Sbjct: 58 LSRTSGGITSSLSSVRV---HPSYSGNN--NDLAILKLSTSIPSGGNIGYARLAASGSDP 112 Query: 137 KPGQTCSVAGWGQTAPLGKHS-HTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIK 195 G + +VAGWG T+ G + L +V + + C + + C G Sbjct: 113 VAGSSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCAGVSSGG 172 Query: 196 KTSFKGDSGGPLV-CNKVAQGIVSYGRNNGMP 226 K S +GDSGGP+V + G VS+G P Sbjct: 173 KDSCQGDSGGPIVDSSNTLIGAVSWGNGCARP 204 >3BEU-A nrPDB Length = 224 Score = 69.7 bits (169), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 59/238 (24%), Positives = 94/238 (39%), Gaps = 29/238 (12%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW---GSSINVTLGAH 77 ++GG A P+M L + CGG L D VLTAAHC G++ ++T Sbjct: 1 VVGGTRAAQGEFPFMVRLSM-------GCGGALYAQDIVLTAAHCVSGSGNNTSITATGG 53 Query: 78 NIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVK 137 + Q + + + + P + + + D L++L QP+ P+ K Sbjct: 54 VVDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKL---------AQPINQPTLKIATT 104 Query: 138 PG---QTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEI 194 T +VAGWG G L + + D C S + +C G Sbjct: 105 TAYNQGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYDTK 164 Query: 195 KKTSFKGDSGGPLVCNKVAQ-----GIVSYGRNNGMPPR--ACTKVSSFVHWIKKTMK 245 ++ + +GDSGGP+ A GIVS+G + T+VS+F I + Sbjct: 165 QEDTCQGDSGGPMFRKDNADEWVQVGIVSWGEGCARKGKYGVYTEVSTFASAIASAAR 222 >1MKW-K nrPDB Length = 308 Score = 68.9 bits (167), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 73/260 (28%), Positives = 109/260 (41%), Gaps = 34/260 (13%) Query: 19 GEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-----WGSSINVT 73 G I+ G +A+ P+ L + L CG LI D +VLTAAHC W + V Sbjct: 48 GRIVEGQDAEVGLSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTVD 106 Query: 74 -----LGAHN-IKEQEPTQQFIPVKRPIPHPAYNPK-NFSNDIMLLQLERKAKRTRAVQP 126 +G H+ + + ++ + + HP YN K N DI LL+L+R + + + P Sbjct: 107 DLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHP 166 Query: 127 LRLPSNKAQVK---PGQTCSVAGWGQ------TAPLGKHSHTLQEVKMTVQEDRKCESDL 177 + LP + K G V GWG T+ LQ V + + E C++ Sbjct: 167 VCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKAST 226 Query: 178 RHYYDSTIELCVG---DPEIKKTSFKGDSGGPLVC-----NKVAQ-GIVSYGRNNGMPPR 228 R + C G + + +GDSGGP V N+ Q GIVS+G + Sbjct: 227 RIRITDNM-FCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEGCDRDGK 285 Query: 229 A--CTKVSSFVHWIKKTMKR 246 T V WI+K + R Sbjct: 286 YGFYTHVFRLKKWIQKVIDR 305 >5UBM-A nrPDB Length = 252 Score = 67.8 bits (164), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 72/255 (28%), Positives = 106/255 (41%), Gaps = 40/255 (15%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 IIGG +A + P+ + GG LI + +VLTAAH + T+ + Sbjct: 2 IIGGSDADIKNFPWQVFF------DNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTS 55 Query: 81 EQEPTQQFIPVKRPIP-----HPAY-------NPKNFSNDIMLLQLERKAKRTRAVQPLR 128 Q T + K P HP + NF NDI L++L+ K V P+ Sbjct: 56 VQ--TSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPIC 113 Query: 129 LP--SNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCE--------SDLR 178 LP S+ + G ++GWG+T + L+ ++ V RKC+ +D Sbjct: 114 LPGTSSDYNLMDGDLGLISGWGRTEKRDRAVR-LKAARLPVAPLRKCKEVKVEKPTADAE 172 Query: 179 HYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNK-------VAQGIVSYGRNNGMPPRACT 231 Y + +C G E S KGDSGG A G+VS+G G T Sbjct: 173 AYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGT-YGLYT 230 Query: 232 KVSSFVHWIKKTMKR 246 +V ++V WI KTM+ Sbjct: 231 RVKNYVDWIMKTMQE 245 >1VR1-H nrPDB Length = 261 Score = 67.4 bits (163), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 73/261 (27%), Positives = 111/261 (42%), Gaps = 34/261 (13%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKR---CGGFLIRDDFVLTAAHC-----WGSSIN- 71 I+ G +A+ P+ L ++S CG LI D +VLTAAHC W + Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 72 ----VTLGAHNIKEQEPTQQFIPVKRPI-PHPAYNPK-NFSNDIMLLQLERKAKRTRAVQ 125 V +G H+ E + I + I HP YN + N DI L++L++ + + Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 120 Query: 126 PLRLPSNKAQ---VKPGQTCSVAGWGQ-----TAPLGK-HSHTLQEVKMTVQEDRKCESD 176 P+ LP + ++ G V GWG TA +GK LQ V + + E C+ Sbjct: 121 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDS 180 Query: 177 LRHYYDSTIELCVGDPEIKK--TSFKGDSGGPLVC-----NKVAQ-GIVSYGRNNGMPPR 228 R + P+ K + +GDSGGP V N+ Q GIVS+G + Sbjct: 181 TRIRITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGK 240 Query: 229 A--CTKVSSFVHWIKKTMKRY 247 T V WI+K + ++ Sbjct: 241 YGFYTHVFRLKKWIQKVIDQF 261 >1ELV-A nrPDB Length = 333 Score = 67.0 bits (162), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 73/262 (27%), Positives = 108/262 (41%), Gaps = 40/262 (15%) Query: 14 PRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVT 73 P + IIGG +A + P+ + GG LI + +VLTAAH + T Sbjct: 76 PFEEKQRIIGGSDADIKNFPWQVFF------DNPWAGGALINEYWVLTAAHVVEGNREPT 129 Query: 74 LGAHNIKEQEPTQQFIPVKRPIP-----HPAY-------NPKNFSNDIMLLQLERKAKRT 121 + + Q T + K P HP + NF NDI L++L+ K Sbjct: 130 MYVGSTSVQ--TSRLAKSKMLTPEHVFIHPGWKLLAVPEGRTNFDNDIALVRLKDPVKMG 187 Query: 122 RAVQPLRLP--SNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCE----- 174 V P+ LP S+ + G ++GWG+T + L+ ++ V RKC+ Sbjct: 188 PTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVR-LKAARLPVAPLRKCKEVKVE 246 Query: 175 ---SDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNK-------VAQGIVSYGRNNG 224 +D Y + +C G E S KGDSGG A G+VS+G G Sbjct: 247 KPTADAEAYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCG 305 Query: 225 MPPRACTKVSSFVHWIKKTMKR 246 T+V ++V WI KTM+ Sbjct: 306 T-YGLYTRVKNYVDWIMKTMQE 326 >6BQM-A nrPDB Length = 506 Score = 67.0 bits (162), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 64/244 (26%), Positives = 106/244 (43%), Gaps = 26/244 (10%) Query: 18 AGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG----SSINVT 73 + IIGG +A PYM L + + CGG + +VLTAAHC + +V Sbjct: 8 SSRIIGGEQATAGEWPYMVALTARNSSHV-FCGGSYLGGRYVLTAAHCVDKEDPAKGDVL 66 Query: 74 LGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNK 133 LGA ++ + T + I V++ H +Y + NDI +L+LER R+VQ + S+ Sbjct: 67 LGAFDMNDVN-TAERIHVRQIYVHNSYITASMGNDIAVLELERDPLPRRSVQ-ISDSSDF 124 Query: 134 AQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQ---------EDRKCESDLRHYYD-- 182 ++ +V G+G + + VQ + + + D ++ Y Sbjct: 125 NELTKDSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGSDQDAKNNYSQL 184 Query: 183 STIELCVGDPEIKKTSFKGDSGGPLVCN----KVAQGIVSYGRNNGMP--PRACTKVSSF 236 + C G K + GD+GGP+ + + G+VS+G G P T +S F Sbjct: 185 TNNAFCAG--SFGKDACSGDAGGPIFFDSNNGRKQMGVVSWGDGCGRANSPGVYTNLSVF 242 Query: 237 VHWI 240 W+ Sbjct: 243 NDWL 246 >4FXG-H nrPDB Length = 242 Score = 67.0 bits (162), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 65/250 (26%), Positives = 107/250 (42%), Gaps = 31/250 (12%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW------GSSINVTL 74 I GG +AKP P+ ++ G L+ D++VLTAAH S++++ + Sbjct: 1 IYGGQKAKPGDFPWQVLIL-----GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRM 55 Query: 75 GAHNIKEQEPTQQFIPVKRPIPHPAY-NPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNK 133 G +K P + H Y + F NDI L++L K + P+ LP + Sbjct: 56 G--TLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKE 113 Query: 134 AQ--VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRH--YYDSTIE--- 186 A+ ++ + +GWG T G + L V + + + +KC + Y ++ Sbjct: 114 AESFMRTDDIGTASGWGLTQR-GFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANM 172 Query: 187 LCVGDPEIKKTSFKGDSGGPLVC------NKVAQGIVSYGRNN---GMPPRACTKVSSFV 237 LC G K S +GD+GG LV GIVS+G N TKV +++ Sbjct: 173 LCAGLESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYI 232 Query: 238 HWIKKTMKRY 247 WI+ + + Sbjct: 233 PWIENIISDF 242 >2FMJ-A nrPDB Length = 222 Score = 67.0 bits (162), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 62/238 (26%), Positives = 93/238 (39%), Gaps = 31/238 (13%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW---GSSINVTLGAH 77 ++GG A P+M L + CGG L D VLTAAHC G++ ++T Sbjct: 1 VVGGTRAAQGEFPFMVRLSM-------GCGGALYAQDIVLTAAHCVSGSGNNTSITATGG 53 Query: 78 NIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVK 137 + Q + + + + P YN D L++L QP+ P+ K Sbjct: 54 VVDLQSSSAVKVRSTKVLQAPGYNGTG--KDWALIKL---------AQPINQPTLKIATT 102 Query: 138 PG---QTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEI 194 T +VAGWG G L + + D C S + + E+C G Sbjct: 103 TAYNQGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSAYGNELVANEEICAGYDTG 162 Query: 195 KKTSFKGDSGGPLVCNKVAQ-----GIVSYGRNNGMPPR--ACTKVSSFVHWIKKTMK 245 + +GDSGGP+ A GIVS+G + T+VS+F I + Sbjct: 163 GVDTCQGDSGGPMFRKDNADEWIQVGIVSWGEGCARKGKYGVYTEVSTFASAIASAAR 220 >1ETT-H nrPDB Length = 259 Score = 67.0 bits (162), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 72/258 (27%), Positives = 108/258 (41%), Gaps = 34/258 (13%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-----WGSSINVT-- 73 I+ G +A+ P+ L + L CG LI D +VLTAAHC W + V Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTVDDL 59 Query: 74 ---LGAHN-IKEQEPTQQFIPVKRPIPHPAYNPK-NFSNDIMLLQLERKAKRTRAVQPLR 128 +G H+ + + ++ + + HP YN K N DI LL+L+R + + + P+ Sbjct: 60 LVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVC 119 Query: 129 LPSNKAQVK---PGQTCSVAGWGQ------TAPLGKHSHTLQEVKMTVQEDRKCESDLRH 179 LP + K G V GWG T+ LQ V + + E C++ R Sbjct: 120 LPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKASTRI 179 Query: 180 YYDSTIELCVG---DPEIKKTSFKGDSGGPLVC-----NKVAQ-GIVSYGRNNGMPPRA- 229 + C G + + +GDSGGP V N+ Q GIVS+G + Sbjct: 180 RITDNM-FCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEGCDRDGKYG 238 Query: 230 -CTKVSSFVHWIKKTMKR 246 T V WI+K + R Sbjct: 239 FYTHVFRLKKWIQKVIDR 256 >3H7T-A nrPDB Length = 235 Score = 66.6 bits (161), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 60/235 (25%), Positives = 100/235 (42%), Gaps = 18/235 (7%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 IIGG ++ P+ +++ D+K CGG ++ +FV+TAA C + + H Sbjct: 1 IIGGKKSDITKEPWAVGVLV-DEKPF--CGGSILTANFVITAAQCVDGTKPSDISIHYGS 57 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAK-RTRAVQPLRLPSNKAQVKPG 139 T+ + + I Y+P N+ +++ E K + + + LPS +P Sbjct: 58 SYRTTKGTSVMAKKIYIVRYHPLTMQNNYAVIETEMPIKLDDKTTKKIELPSLLYDPEPD 117 Query: 140 QTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDL------RHYYDSTIELCVGDP 192 + V+GWG T ++S L E TV + + CE ++ YD C G Sbjct: 118 TSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGV--FCAGGE 175 Query: 193 EIKKTSFKGDSGGPLVCNKVAQGIVSYGRNNGMP---PRACTKVSSFVHWIKKTM 244 + GD+G P V N G+ SY + MP P +V +V IK + Sbjct: 176 YDETYIGYGDAGDPAVQNGTLVGVASY--ISSMPSEFPSVFLRVGYYVLDIKDII 228 >2KAI-A nrPDB Length = 80 Score = 66.6 bits (161), Expect = 1e-11, Method: Composition-based stats. Identities = 35/81 (43%), Positives = 46/81 (56%), Gaps = 3/81 (3%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 IIGG E + +S P+ + I+ S + CGG L+ +VLTAAHC + V LG HN+ Sbjct: 1 IIGGRECEKNSHPWQ--VAIYHYSSFQ-CGGVLVNPKWVLTAAHCKNDNYEVWLGRHNLF 57 Query: 81 EQEPTQQFIPVKRPIPHPAYN 101 E E T QF V PHP +N Sbjct: 58 ENENTAQFFGVTADFPHPGFN 78 >4J1Y-A nrPDB Length = 397 Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 72/262 (27%), Positives = 107/262 (40%), Gaps = 40/262 (15%) Query: 14 PRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVT 73 P + IGG +A + P+ + GG LI + +VLTAAH + T Sbjct: 140 PFEEKARAIGGSDADIKNFPWQVFF------DNPWAGGALINEYWVLTAAHVVEGNREPT 193 Query: 74 LGAHNIKEQEPTQQFIPVKRPIP-----HPAY-------NPKNFSNDIMLLQLERKAKRT 121 + + Q T + K P HP + NF NDI L++L+ K Sbjct: 194 MYVGSTSVQ--TSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMG 251 Query: 122 RAVQPLRLP--SNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCE----- 174 V P+ LP S+ + G ++GWG+T + L+ ++ V RKC+ Sbjct: 252 PTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVR-LKAARLPVAPLRKCKEVKVE 310 Query: 175 ---SDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNK-------VAQGIVSYGRNNG 224 +D Y + +C G E S KGDSGG A G+VS+G G Sbjct: 311 KPTADAEAYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCG 369 Query: 225 MPPRACTKVSSFVHWIKKTMKR 246 T+V ++V WI KTM+ Sbjct: 370 T-YGLYTRVKNYVDWIMKTMQE 390 >5TO3-B nrPDB Length = 409 Score = 64.7 bits (156), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 74/259 (28%), Positives = 110/259 (42%), Gaps = 34/259 (13%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-----WGSSIN---- 71 I+ G +A+ P+ L + L CG LI D +VLTAAHC W + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 59 Query: 72 -VTLGAHNIKEQEPTQQFIPVKRPI-PHPAYNPK-NFSNDIMLLQLERKAKRTRAVQPLR 128 V +G H+ E + I + I HP YN + N DI L++L++ + + P+ Sbjct: 60 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 119 Query: 129 LPSNKAQ---VKPGQTCSVAGWGQ-----TAPLGK-HSHTLQEVKMTVQEDRKCESDLRH 179 LP + ++ G V GWG TA +GK LQ V + + E C+ R Sbjct: 120 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRI 179 Query: 180 YYDSTIELCVG---DPEIKKTSFKGDSGGPLVC-----NKVAQ-GIVSYGRNNGMPPRA- 229 + C G D + + +GDSGGP V N+ Q GIVS G + Sbjct: 180 RITDNM-FCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAGAGCDRDGKYG 238 Query: 230 -CTKVSSFVHWIKKTMKRY 247 T V WI+K + ++ Sbjct: 239 FYTHVFRLKKWIQKVIDQF 257 >2OCV-B nrPDB Length = 259 Score = 63.9 bits (154), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 71/259 (27%), Positives = 111/259 (42%), Gaps = 34/259 (13%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-----WGSSIN---- 71 I+ G +A+ P+ L + L CG LI D +VLTAAHC W + Sbjct: 1 IVEGWDAEKGIAPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCILYPPWDKNFTENDL 59 Query: 72 -VTLGAHNIKEQEPTQQFIPVKRPI-PHPAYNPK-NFSNDIMLLQLERKAKRTRAVQPLR 128 V +G H+ E + I + I HP YN + N DI LL+L++ + + P+ Sbjct: 60 LVRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVC 119 Query: 129 LPSNK---AQVKPGQTCSVAGWGQ-----TAPLGK-HSHTLQEVKMTVQEDRKCESDLRH 179 LP + + ++ G V GWG T + + LQ V + + E C++ R Sbjct: 120 LPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRI 179 Query: 180 YYDSTIELCVG---DPEIKKTSFKGDSGGPLVC-----NKVAQ-GIVSYGRNNGMPPRA- 229 + C G + + + +GDSGGP V N+ Q GIVS+G + Sbjct: 180 RITDNM-FCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRKGKYG 238 Query: 230 -CTKVSSFVHWIKKTMKRY 247 T V WI+K + ++ Sbjct: 239 FYTHVFRLKAWIQKVIDQF 257 >1YM0-A nrPDB Length = 238 Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 63/248 (25%), Positives = 100/248 (40%), Gaps = 33/248 (13%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKR-------CGGFLIRDDFVLTAAHCWGSS---- 69 I+GG EA+P+ P+ Q S++R CGG +I D +V+ AAHC Sbjct: 1 IVGGIEARPYEFPW--------QVSVRRKSSDSHFCGGSIINDRWVVCAAHCMQGEAPAL 52 Query: 70 INVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRL 129 +++ +G H+ +Q V + Y+P ND+ +++ V P+ Sbjct: 53 VSLVVGEHDSSAASTVRQTHDVDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICA 112 Query: 130 --PSNKAQVKPGQTCSVAGWGQTAPLGKHS-HTLQEVKMTVQEDRKCESDLRH--YYDST 184 P+N + Q CS GWG G L+ V + + + C++ YD Sbjct: 113 PDPANDYVYRKSQ-CS--GWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYDDM 169 Query: 185 IELCVGDPEIKKTSFKGDSGGPLVCNKVAQ-----GIVSYGRNNGMP-PRACTKVSSFVH 238 I + S +GDSGGPL + GIVS+G P ++V Sbjct: 170 ICATDNTGMTDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWGIGCASGYPGVYSRVGFHAG 229 Query: 239 WIKKTMKR 246 WI T+ Sbjct: 230 WITDTITN 237 >4BXW-A nrPDB Length = 423 Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 66/246 (26%), Positives = 107/246 (43%), Gaps = 24/246 (9%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNI- 79 I+ G + K P+ A L+ D+K CGG ++ +VLTAAHC + +++ I Sbjct: 170 IVNGMDCKLGECPWQAALV--DEKEGVFCGGTILSPIYVLTAAHCINETETISVVVGEID 227 Query: 80 KEQEPTQQFIPVKRPIPHPAYNP---------KNFSNDIMLLQLERKAKRTRAVQPLRLP 130 K + T + V + H + P + DI ++Q++ + + V P LP Sbjct: 228 KSRIETGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQFSENVVPACLP 287 Query: 131 SNK--AQVKPGQTCS-VAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIEL 187 + QV Q V+G+G+ G S TL+ +K+ + C + Sbjct: 288 TADFANQVLMKQDFGIVSGFGRIVEKGPKSKTLKVLKVPYVDRHTCMVSSETPITPNM-F 346 Query: 188 CVGDPEIKKTSFKGDSGGPLVC----NKVAQGIVSYGRN---NGMPPRACTKVSSFVHWI 240 C G + + + +GDSGGP GIVS G NG TK+S F+ WI Sbjct: 347 CAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSGEGCARNGKYGNY-TKLSKFIPWI 405 Query: 241 KKTMKR 246 K+ M++ Sbjct: 406 KRIMRQ 411 >1EPT-B nrPDB Length = 82 Score = 62.8 bits (151), Expect = 1e-10, Method: Composition-based stats. Identities = 33/83 (39%), Positives = 42/83 (50%), Gaps = 2/83 (2%) Query: 68 SSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPL 127 S I V LG HNI E +QFI + I HP +N NDIML++L A V + Sbjct: 1 SRIQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATV 60 Query: 128 RLPSNKAQVKPGQTCSVAGWGQT 150 LP + A G C ++GWG T Sbjct: 61 SLPRSCAAA--GTECLISGWGNT 81 >4X0L-C nrPDB Length = 259 Score = 61.6 bits (148), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 66/259 (25%), Positives = 114/259 (44%), Gaps = 52/259 (20%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAH--CWGSSINVTLGAHN 78 I+GGH S P+ A ++ +L G LI + ++LT A S N T Sbjct: 15 ILGGHLDAKGSFPWQAKMV--SHHNL-TTGATLINEQWLLTTAKNLFLNHSENAT----- 66 Query: 79 IKEQEPT-------QQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPS 131 K+ PT +Q + +++ + HP Y+ DI L++L++K V P+ LPS Sbjct: 67 AKDIAPTLTLYVGKKQLVEIEKVVLHPNYS----QVDIGLIKLKQKVSVNERVMPICLPS 122 Query: 132 NKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTI------ 185 K + G+ V+GWG+ A K + L+ V + V + +C +RHY ST+ Sbjct: 123 -KDYAEVGRVGYVSGWGRNANF-KFTDHLKYVMLPVADQDQC---IRHYEGSTVPEKKTP 177 Query: 186 -------------ELCVGDPEIKKTSFKGDSGGPLVCNKV------AQGIVSYGRNNGMP 226 C G + ++ + GD+G + + A GI+S+ ++ + Sbjct: 178 KSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVA 237 Query: 227 PRAC-TKVSSFVHWIKKTM 244 KV+S W++KT+ Sbjct: 238 EYGVYVKVTSIQDWVQKTI 256 >4WJG-C nrPDB Length = 315 Score = 61.2 bits (147), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 65/257 (25%), Positives = 115/257 (44%), Gaps = 48/257 (18%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 I+GGH S P+ A ++ +L G LI + ++LT A +N + A K Sbjct: 71 ILGGHLDAKGSFPWQAKMV--SHHNLTT-GATLINEQWLLTTAK--NLFLNHSENA-TAK 124 Query: 81 EQEPT-------QQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNK 133 + PT +Q + +++ + HP Y+ DI L++L++K V P+ LPS K Sbjct: 125 DIAPTLTLYVGKKQLVEIEKVVLHPNYS----QVDIGLIKLKQKVSVNERVMPICLPS-K 179 Query: 134 AQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTI-------- 185 + G+ V+GWG+ A K + L+ V + V + +C +RHY ST+ Sbjct: 180 DYAEVGRVGYVSGWGRNANF-KFTDHLKYVMLPVADQDQC---IRHYEGSTVPEKKTPKS 235 Query: 186 -----------ELCVGDPEIKKTSFKGDSGGPLVCNKV------AQGIVSYGRNNGMPPR 228 C G + ++ + GD+G + + A GI+S+ ++ + Sbjct: 236 PVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAEY 295 Query: 229 AC-TKVSSFVHWIKKTM 244 KV+S W++KT+ Sbjct: 296 GVYVKVTSIQDWVQKTI 312 >1DLE-A nrPDB Length = 298 Score = 57.8 bits (138), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 62/239 (25%), Positives = 107/239 (44%), Gaps = 57/239 (23%) Query: 30 HSRPYMAYL-MIWDQKSLKRCGGFLIRDDFVLTAAHCWG-----SSINVTLGAHNIKEQE 83 H +P+ A + +I K + C G ++ + FVLTAAHC+ SI V++G Sbjct: 25 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGGE------ 78 Query: 84 PTQQFIPVKRPIPHPAYN---------PKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKA 134 ++ + ++ + HP YN P+ + D+ L++L+ K K + ++P+ LP + Sbjct: 79 --KRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEG 136 Query: 135 QVK-----PGQTCSVAGWGQTAPLGKHSHTL---QEVKMTVQE------DRK--CESDLR 178 + P TC + P +E K+T +E D+K CE D + Sbjct: 137 TTRALRLPPTTTCQQQK-EELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQ 195 Query: 179 HY--YDSTIE---------LCVG--DPEIKKTSFKGDSGGPLVCNK----VAQGIVSYG 220 + YD + LC G P + +GDSGGPL+ +K + G++S+G Sbjct: 196 YAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 254 >2WIN-I nrPDB Length = 507 Score = 57.8 bits (138), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 62/239 (25%), Positives = 107/239 (44%), Gaps = 57/239 (23%) Query: 30 HSRPYMAYL-MIWDQKSLKRCGGFLIRDDFVLTAAHCWG-----SSINVTLGAHNIKEQE 83 H +P+ A + +I K + C G ++ + FVLTAAHC+ SI V++G Sbjct: 232 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGGE------ 285 Query: 84 PTQQFIPVKRPIPHPAYN---------PKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKA 134 ++ + ++ + HP YN P+ + D+ L++L+ K K + ++P+ LP + Sbjct: 286 --KRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEG 343 Query: 135 QVK-----PGQTCSVAGWGQTAPLGKHSHTL---QEVKMTVQE------DRK--CESDLR 178 + P TC + P +E K+T +E D+K CE D + Sbjct: 344 TTRALRLPPTTTCQQQK-EELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQ 402 Query: 179 HY--YDSTIE---------LCVG--DPEIKKTSFKGDSGGPLVCNK----VAQGIVSYG 220 + YD + LC G P + +GDSGGPL+ +K + G++S+G Sbjct: 403 YAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 461 >2OK5-A nrPDB Length = 752 Score = 57.0 bits (136), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 62/239 (25%), Positives = 107/239 (44%), Gaps = 57/239 (23%) Query: 30 HSRPYMAYL-MIWDQKSLKRCGGFLIRDDFVLTAAHCWG-----SSINVTLGAHNIKEQE 83 H +P+ A + +I K + C G ++ + FVLTAAHC+ SI V++G Sbjct: 476 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGGE------ 529 Query: 84 PTQQFIPVKRPIPHPAYN---------PKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKA 134 ++ + ++ + HP YN P+ + D+ L++L+ K K + ++P+ LP + Sbjct: 530 --KRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEG 587 Query: 135 QVK-----PGQTCSVAGWGQTAPLGKHSHTL---QEVKMTVQE------DRK--CESDLR 178 + P TC + P +E K+T +E D+K CE D + Sbjct: 588 TTRALRLPPTTTCQQQK-EELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQ 646 Query: 179 HY--YDSTIE---------LCVG--DPEIKKTSFKGDSGGPLVCNK----VAQGIVSYG 220 + YD + LC G P + +GDSGGPL+ +K + G++S+G Sbjct: 647 YAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 705 >4F4O-C nrPDB Length = 347 Score = 57.0 bits (136), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 66/256 (25%), Positives = 110/256 (42%), Gaps = 46/256 (17%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHN-- 78 I+GG S P+ A ++ +L G LI + ++LT A N+ LG N Sbjct: 103 IMGGSLDAKGSFPWQAKMI--SHHNLTS-GATLINEQWLLTTAK------NLRLGHKNDT 153 Query: 79 -IKEQEPTQQFIPVKR---PIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKA 134 K+ PT + K+ I ++P N + DI L++L++K V P+ LPS K Sbjct: 154 KAKDIAPTLRLYVGKKQEVEIEKVIFHPDNSTVDIGLIKLKQKVPVNERVMPICLPS-KD 212 Query: 135 QVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTI--------- 185 V G V+GWG+ A L H L+ V + V + KC +++Y ST+ Sbjct: 213 YVNVGLVGYVSGWGRNANLNFTEH-LKYVMLPVADQEKC---VQYYEGSTVPEKKTPKSP 268 Query: 186 ----------ELCVGDPEIKKTSFKGDSGGPLVCNK------VAQGIVSYGRNNGMPPRA 229 C G + ++ + GD+G + A GI+S+ ++ Sbjct: 269 VGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKDDDTWYAAGILSFDKSCRTAEYG 328 Query: 230 C-TKVSSFVHWIKKTM 244 +V+S + WI+ T+ Sbjct: 329 VYVRVTSILDWIQTTI 344 >1AKS-B nrPDB Length = 98 Score = 56.2 bits (134), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 34/87 (39%), Positives = 49/87 (56%), Gaps = 3/87 (3%) Query: 160 LQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSY 219 LQ +K V + C+S + +CVG + K S +GDSGGP+VCN QGIVS+ Sbjct: 10 LQCLKAPVLSNSSCKSSYPGQITGNM-ICVGFLQGGKDSCQGDSGGPVVCNGQLQGIVSW 68 Query: 220 GRNNGM--PPRACTKVSSFVHWIKKTM 244 G P TKV ++V+WI++T+ Sbjct: 69 GYGCAQKNKPGVYTKVCNYVNWIQQTI 95 >1BBR-H nrPDB Length = 150 Score = 54.7 bits (130), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 43/144 (29%), Positives = 65/144 (45%), Gaps = 16/144 (11%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-----WGSSINVT-- 73 I+ G +A+ P+ L + L CG LI D +VLTAAHC W + V Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTVDDL 59 Query: 74 ---LGAHN-IKEQEPTQQFIPVKRPIPHPAYNPK-NFSNDIMLLQLERKAKRTRAVQPLR 128 +G H+ + + ++ + + HP YN K N DI LL+L+R + + + P+ Sbjct: 60 LVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVC 119 Query: 129 LPSNKAQVK---PGQTCSVAGWGQ 149 LP + K G V GWG Sbjct: 120 LPDKQTAAKLLHAGFKGRVTGWGN 143 >1RIW-B nrPDB Length = 147 Score = 50.8 bits (120), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 42/144 (29%), Positives = 65/144 (45%), Gaps = 16/144 (11%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-----WGSSIN---- 71 I+ G +A+ P+ L + L CG LI D +VLTAAHC W + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 59 Query: 72 -VTLGAHNIKEQEPTQQFIPVKRPI-PHPAYNPK-NFSNDIMLLQLERKAKRTRAVQPLR 128 V +G H+ E + I + I HP YN + N DI L++L++ + + P+ Sbjct: 60 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 119 Query: 129 LPSNK---AQVKPGQTCSVAGWGQ 149 LP + + ++ G V GWG Sbjct: 120 LPDRETAASLLQAGYKGRVTGWGN 143 >2I6S-A nrPDB Length = 517 Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 37/116 (31%), Positives = 60/116 (51%), Gaps = 19/116 (16%) Query: 44 KSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIKEQEPTQQF---IPVKRPIPHPAY 100 KS + C G LI D +VLTAAHC+ + +L N+ +P Q+ +++ + P + Sbjct: 252 KSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVG--DPKSQWGKEFLIEKAVISPGF 309 Query: 101 N---PKN------FSNDIMLLQLERKAKRTRAVQPLRLP----SNKAQVKP-GQTC 142 + KN + +DI LL+L +K K + +P+ LP +N A +P G TC Sbjct: 310 DVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQGSTC 365 >3RU4-E nrPDB Length = 96 Score = 43.5 bits (101), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 28/94 (29%), Positives = 50/94 (53%), Gaps = 15/94 (15%) Query: 160 LQEVKMTVQEDRKCESDLRHYYDSTIE---LCVGDPEIKKTSFKGDSGGPLVCNKVAQ-- 214 LQ+ + + + C + Y+ + I+ +C G + +S GDSGGPLVC K Sbjct: 6 LQQASLPLLSNTNC----KKYWGTKIKDAMICAGASGV--SSCMGDSGGPLVCKKNGAWT 59 Query: 215 --GIVSYGRN--NGMPPRACTKVSSFVHWIKKTM 244 GIVS+G + + P +V++ V+W+++T+ Sbjct: 60 LVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTL 93 >3F1S-B nrPDB Length = 283 Score = 42.0 bits (97), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 25/68 (36%), Positives = 36/68 (52%), Gaps = 3/68 (4%) Query: 49 CGGFLIRDDFVLTAAHCWGSSINVTLGAH-NIKEQEPTQQFIPVKRPIPHPAYNPKNFSN 107 CGG +IR++FVLT A C N+T+ + N Q+P I + H Y+ N Sbjct: 79 CGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDPL--MIKITHVHVHMRYDADAGEN 136 Query: 108 DIMLLQLE 115 D+ LL+LE Sbjct: 137 DLSLLELE 144 >3H5C-B nrPDB Length = 317 Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 25/68 (36%), Positives = 36/68 (52%), Gaps = 3/68 (4%) Query: 49 CGGFLIRDDFVLTAAHCWGSSINVTLGAH-NIKEQEPTQQFIPVKRPIPHPAYNPKNFSN 107 CGG +IR++FVLT A C N+T+ + N Q+P I + H Y+ N Sbjct: 120 CGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDPL--MIKITHVHVHMRYDADAGEN 177 Query: 108 DIMLLQLE 115 D+ LL+LE Sbjct: 178 DLSLLELE 185 >2JET-C nrPDB Length = 99 Score = 37.4 bits (85), Expect = 0.006, Method: Compositional matrix adjust. Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 11/81 (13%) Query: 174 ESDLRHYYDSTIE---LCVGDPEIKKTSFKGDSGGPLVCNK----VAQGIVSYGRN--NG 224 E+D + + S I C G + S GDSGGPLVC K GIVS+G + Sbjct: 19 EADCKKSWGSKITDVMTCAGASGVD--SCMGDSGGPLVCQKDGVWTLAGIVSWGSGVCST 76 Query: 225 MPPRACTKVSSFVHWIKKTMK 245 P ++V++ + W+++ ++ Sbjct: 77 STPGVYSRVTALMPWVQQILE 97 >2EA3-A nrPDB Length = 189 Score = 32.7 bits (73), Expect = 0.16, Method: Compositional matrix adjust. Identities = 42/178 (23%), Positives = 59/178 (33%), Gaps = 36/178 (20%) Query: 47 KRCG-GFLIRDDFVLTAAHCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNF 105 RC GF + F+ TA HC G PT F P A+ Sbjct: 15 SRCSIGFAVNGGFI-TAGHC---------GRTGATTANPTGTFAGSSFPGNDYAFVRTGA 64 Query: 106 SNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKM 165 +++ R + P A + G T GW H T+ + Sbjct: 65 GVNLLAQVNNYSGGRVQVAGHTAAPVGSAVCRSGST---TGW--------HCGTITALNS 113 Query: 166 TVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNN 223 +V E +R +T+ C +P GDSGG L+ AQG+ S G N Sbjct: 114 SVTYP---EGTVRGLIRTTV--CA-EP--------GDSGGSLLAGNQAQGVTSGGSGN 157 >2HNT-C nrPDB Length = 70 Score = 31.2 bits (69), Expect = 0.41, Method: Compositional matrix adjust. Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 1/45 (2%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC 65 I+ G +A+ P+ L + L CG LI D +VLTAAHC Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHC 44 >5LAK-A nrPDB Length = 314 Score = 29.6 bits (65), Expect = 1.1, Method: Compositional matrix adjust. Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 11/98 (11%) Query: 49 CGGFLIRDDFVLTAAHCWGSS----INVTLGAHNI----KEQEPTQQFIPVKRPIPHPAY 100 CGG L L HC GS ++ T G NI K Q P++ I + I P Sbjct: 153 CGGMLFDPKGRLLGLHCAGSDDVVFMDTTTGKSNIWTSYKLQHPSEIMITLNNEINLP-- 210 Query: 101 NPKNFSNDIMLLQLERKAKRTRA-VQPLRLPSNKAQVK 137 NP N+ + + + + A ++ L+ +NK K Sbjct: 211 NPANYDFETTKVVYQHPLRNVCATLETLQHLTNKTNAK 248 >3WSY-A nrPDB Length = 678 Score = 28.9 bits (63), Expect = 2.0, Method: Compositional matrix adjust. Identities = 11/33 (33%), Positives = 19/33 (57%) Query: 167 VQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 199 +ED +C+ + D ++E+CV DPE S+ Sbjct: 594 TREDYECDFGFKMSEDLSLEVCVPDPEFSGKSY 626 >1CDO-A nrPDB Length = 374 Score = 27.7 bits (60), Expect = 5.3, Method: Compositional matrix adjust. Identities = 14/29 (48%), Positives = 18/29 (62%), Gaps = 3/29 (10%) Query: 132 NKAQVKPGQTCSVAGWGQT---APLGKHS 157 N A+V+PG TC+V G G A +G HS Sbjct: 186 NTAKVEPGSTCAVFGLGAVGLAAVMGCHS 214 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1IAU-A nrPDB 347 2e-96 1FI8-A nrPDB 327 2e-90 5FXL-A nrPDB 327 3e-90 1UTJ-A nrPDB 327 3e-90 1F7Z-A nrPDB 327 4e-90 4AN7-A nrPDB 325 1e-89 1EUF-A nrPDB 324 2e-89 5C67-A nrPDB 312 6e-86 4WWY-A nrPDB 312 8e-86 1A0J-A nrPDB 312 1e-85 3TK9-A nrPDB 305 1e-83 3G01-A nrPDB 300 3e-82 1NN6-A nrPDB 299 7e-82 2TLD-E nrPDB 297 4e-81 5TJX-A nrPDB 294 3e-80 6I44-A nrPDB 293 4e-80 1FXY-A nrPDB 293 5e-80 5GVT-A nrPDB 292 1e-79 1SGF-G nrPDB 289 6e-79 2EEK-A nrPDB 289 9e-79 4NFE-A nrPDB 287 4e-78 1KYN-A nrPDB 285 2e-77 2F83-A nrPDB 283 3e-77 1SPJ-A nrPDB 278 1e-75 3W94-A nrPDB 278 2e-75 5UGG-A nrPDB 277 3e-75 4DUR-A nrPDB 277 3e-75 3RP2-A nrPDB 276 5e-75 3T2N-A nrPDB 275 1e-74 5MS3-A nrPDB 275 1e-74 4DGJ-A nrPDB 274 3e-74 1KIG-H nrPDB 272 8e-74 1X7A-C nrPDB 272 8e-74 1EKB-B nrPDB 272 8e-74 1NPM-A nrPDB 272 1e-73 6AOD-C nrPDB 272 1e-73 3QUM-P nrPDB 272 1e-73 3K65-B nrPDB 271 2e-73 3LC3-A nrPDB 270 3e-73 1TON-A nrPDB 270 3e-73 3NXP-A nrPDB 270 4e-73 2RDL-A nrPDB 270 4e-73 4GSO-A nrPDB 270 5e-73 2PSX-A nrPDB 269 6e-73 3BSQ-A nrPDB 269 8e-73 4NZQ-A nrPDB 269 9e-73 1AO5-A nrPDB 269 9e-73 1BRU-P nrPDB 269 9e-73 1P57-B nrPDB 268 1e-72 4MPW-A nrPDB 267 2e-72 5ZFH-A nrPDB 267 5e-72 1MKW-K nrPDB 266 6e-72 2F91-A nrPDB 266 6e-72 1FUJ-A nrPDB 265 1e-71 4H4F-A nrPDB 265 2e-71 3E0N-B nrPDB 265 2e-71 3DFJ-A nrPDB 264 2e-71 1LTO-A nrPDB 264 2e-71 1SGF-A nrPDB 264 2e-71 1C5M-D nrPDB 264 2e-71 1FDP-A nrPDB 264 3e-71 2AIQ-A nrPDB 263 4e-71 6QHB-A nrPDB 263 4e-71 3S9B-A nrPDB 262 1e-70 2CGA-A nrPDB 262 1e-70 4E7N-A nrPDB 261 3e-70 1PYT-D nrPDB 260 4e-70 5FCR-A nrPDB 259 7e-70 3P8G-A nrPDB 258 2e-69 2OCV-B nrPDB 258 2e-69 1ORF-A nrPDB 257 2e-69 2V35-A nrPDB 257 3e-69 1VR1-H nrPDB 257 3e-69 1ETT-H nrPDB 254 2e-68 4Z6A-H nrPDB 253 4e-68 1OP0-A nrPDB 253 7e-68 1ELT-A nrPDB 253 7e-68 1GVZ-A nrPDB 253 7e-68 2BDH-A nrPDB 252 7e-68 1MZD-A nrPDB 252 8e-68 1YC0-A nrPDB 252 1e-67 3S69-A nrPDB 251 2e-67 3F6U-H nrPDB 251 2e-67 1BQY-A nrPDB 250 4e-67 1BDA-A nrPDB 250 5e-67 1FIZ-A nrPDB 248 1e-66 2R0L-A nrPDB 248 2e-66 1SC8-U nrPDB 246 5e-66 1FIW-A nrPDB 246 7e-66 1A5I-A nrPDB 246 8e-66 5LHN-A nrPDB 245 9e-66 2OQ5-A nrPDB 245 1e-65 5TO3-B nrPDB 244 2e-65 4XDE-A nrPDB 243 6e-65 4Q7Y-A nrPDB 243 7e-65 1FON-A nrPDB 241 2e-64 1AZZ-A nrPDB 239 9e-64 4IW4-E nrPDB 235 2e-62 1EQ9-A nrPDB 234 2e-62 5XRF-A nrPDB 234 3e-62 4KKD-A nrPDB 233 5e-62 4IGD-A nrPDB 233 6e-62 1Q3X-A nrPDB 231 1e-61 4BXW-A nrPDB 231 2e-61 2ZKS-A nrPDB 230 3e-61 1ZJK-A nrPDB 230 6e-61 1AE5-A nrPDB 229 8e-61 5LPF-A nrPDB 228 2e-60 4DJZ-B nrPDB 228 2e-60 2XRC-A nrPDB 227 3e-60 2OLG-A nrPDB 227 3e-60 2QY0-B nrPDB 227 3e-60 1GPZ-A nrPDB 226 5e-60 1MD7-A nrPDB 225 2e-59 5KWM-A nrPDB 225 2e-59 4FXG-H nrPDB 225 2e-59 2XXL-A nrPDB 223 5e-59 5O32-I nrPDB 222 8e-59 1PPF-E nrPDB 222 1e-58 5UBM-A nrPDB 221 2e-58 1YM0-A nrPDB 221 3e-58 1ELV-A nrPDB 219 7e-58 2B9L-A nrPDB 216 6e-57 4J1Y-A nrPDB 215 2e-56 3I77-A nrPDB 213 4e-56 6BQM-A nrPDB 212 1e-55 2ASU-B nrPDB 208 2e-54 2HLC-A nrPDB 207 3e-54 3BEU-A nrPDB 207 3e-54 4LK4-A nrPDB 207 4e-54 1PQ7-A nrPDB 206 5e-54 2FMJ-A nrPDB 202 1e-52 1SI5-H nrPDB 198 2e-51 1M9U-A nrPDB 196 8e-51 4X0L-C nrPDB 196 1e-50 4WJG-C nrPDB 195 2e-50 4F4O-C nrPDB 194 3e-50 5XW8-A nrPDB 193 5e-50 3H7O-A nrPDB 191 2e-49 3H7T-A nrPDB 191 3e-49 2PKA-B nrPDB 177 3e-45 3VGC-B nrPDB 167 4e-42 2JET-B nrPDB 164 2e-41 1RIW-B nrPDB 161 4e-40 1BBR-H nrPDB 154 2e-38 1AKS-B nrPDB 140 7e-34 2WIN-I nrPDB 138 3e-33 1DLE-A nrPDB 135 1e-32 2OK5-A nrPDB 134 4e-32 2KAI-A nrPDB 120 5e-28 1EPT-B nrPDB 114 3e-26 2I6S-A nrPDB 109 1e-24 3RU4-E nrPDB 98 3e-21 3F1S-B nrPDB 97 6e-21 3H5C-B nrPDB 95 3e-20 Sequences not found previously or not previously below threshold: 2HNT-F nrPDB 111 4e-25 1BBR-E nrPDB 109 8e-25 2JET-C nrPDB 98 4e-21 2HNT-E nrPDB 83 1e-16 2HNT-C nrPDB 81 4e-16 1P3E-A nrPDB 42 2e-04 2EA3-A nrPDB 37 0.007 2PFE-A nrPDB 36 0.011 2OUA-A nrPDB 36 0.020 2SFA-A nrPDB 34 0.058 5JYK-A nrPDB 34 0.063 5ILA-A nrPDB 33 0.12 5ILB-A nrPDB 33 0.12 4FLN-A nrPDB 33 0.12 2SGA-A nrPDB 32 0.18 3LT3-A nrPDB 32 0.20 1DUE-A nrPDB 31 0.37 4V1Y-A nrPDB 31 0.55 2HRV-A nrPDB 31 0.68 3W95-A nrPDB 30 1.1 4FVB-A nrPDB 30 1.1 4NCX-A nrPDB 30 1.2 3H7V-A nrPDB 29 1.9 1HPG-A nrPDB 29 2.1 6HQA-B nrPDB 29 2.1 1U1U-A nrPDB 29 2.5 5XIP-A nrPDB 28 3.3 4NSY-A nrPDB 28 3.3 4XZB-A nrPDB 28 4.1 4A8B-A nrPDB 27 6.1 3STJ-A nrPDB 27 6.1 3STI-A nrPDB 27 6.1 3MH6-A nrPDB 27 6.6 3COS-A nrPDB 27 7.0 2M5T-A nrPDB 27 8.5 1CDO-A nrPDB 27 8.6 >1IAU-A nrPDB Length = 227 Score = 347 bits (892), Expect = 2e-96, Method: Composition-based stats. Identities = 227/227 (100%), Positives = 227/227 (100%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 60 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 140 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ Sbjct: 61 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 120 Query: 141 TCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFK 200 TCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFK Sbjct: 121 TCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFK 180 Query: 201 GDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMKRY 247 GDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMKRY Sbjct: 181 GDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMKRY 227 >1FI8-A nrPDB Length = 228 Score = 327 bits (840), Expect = 2e-90, Method: Composition-based stats. Identities = 158/227 (69%), Positives = 185/227 (81%), Gaps = 1/227 (0%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQ-KSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNI 79 IIGGHEAKPHSRPYMAYL I D+ K+CGGFLIR+DFVLTAAHC GS I VTLGAHNI Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKIQVTLGAHNI 60 Query: 80 KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 KEQE QQ IPV + IPHPAYN K SNDIMLL+L+ KAKR+ AV+PL LP +VKPG Sbjct: 61 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 120 Query: 140 QTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 199 C VAGWG+ P+GK+S TLQEV++TVQED+KCES L++Y+D E+C GDP+IK+ SF Sbjct: 121 DVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASF 180 Query: 200 KGDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMKR 246 +GDSGGPLVC KVA GIVSYG+N+G PRA TKVS+F+ WIKKTMK+ Sbjct: 181 RGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMKK 227 >5FXL-A nrPDB Length = 246 Score = 327 bits (839), Expect = 3e-90, Method: Composition-based stats. Identities = 89/244 (36%), Positives = 126/244 (51%), Gaps = 10/244 (4%) Query: 4 ILLLLAFLLLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAA 63 + LL A + P D +I+GG+ ++ PY L CGG LI +V++AA Sbjct: 7 LALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSL----NSGYHFCGGSLINSQWVVSAA 62 Query: 64 HCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRA 123 HC+ S I V LG NI E +QFI + I HP+YN +NDIML++L+ A Sbjct: 63 HCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSR 122 Query: 124 VQPLRLPSNKAQVKPGQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYD 182 V + LP++ A G C ++GWG T G + L+ +K + D C+S Sbjct: 123 VASISLPTSCAS--AGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQIT 180 Query: 183 STIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNNGM--PPRACTKVSSFVHWI 240 S + C G E K S +GDSGGP+VC+ QGIVS+G P TKV ++V WI Sbjct: 181 SNM-FCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWI 239 Query: 241 KKTM 244 K+T+ Sbjct: 240 KQTI 243 >1UTJ-A nrPDB Length = 242 Score = 327 bits (838), Expect = 3e-90, Method: Composition-based stats. Identities = 92/249 (36%), Positives = 131/249 (52%), Gaps = 13/249 (5%) Query: 5 LLLLAFLLLPR----ADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVL 60 ++ L F+LL + +I+GG+E KP+S+P+ L CGG L+ +++V+ Sbjct: 1 MISLVFVLLIGAAFATEDDKIVGGYECKPYSQPHQVSL----NSGYHFCGGSLVNENWVV 56 Query: 61 TAAHCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKR 120 +AAHC+ S + V LG HNIK E ++QFI R I HP Y+ N NDIML++L + A Sbjct: 57 SAAHCYKSRVEVRLGEHNIKVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPATL 116 Query: 121 TRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHY 180 VQP+ LP++ A G C+V+GWG T S+ LQ + + + C + Sbjct: 117 NTYVQPVALPTSCA--PAGTMCTVSGWGNTMSSTADSNKLQCLNIPILSYSDCNNSYPGM 174 Query: 181 YDSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNNGMP--PRACTKVSSFVH 238 C G E K S +GDSGGP+VCN QG+VS+G P P KV F Sbjct: 175 IT-NAMFCAGYLEGGKDSCQGDSGGPVVCNGELQGVVSWGYGCAEPGNPGVYAKVCIFND 233 Query: 239 WIKKTMKRY 247 W+ TM Y Sbjct: 234 WLTSTMASY 242 >1F7Z-A nrPDB Length = 233 Score = 327 bits (838), Expect = 4e-90, Method: Composition-based stats. Identities = 88/236 (37%), Positives = 121/236 (51%), Gaps = 10/236 (4%) Query: 12 LLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSIN 71 P D I+GG+ + +S PY L CGG LI D +V++AAHC+ S I Sbjct: 2 AFPVDDDDAIVGGYTCQENSVPYQVSL----NSGYHFCGGSLINDQWVVSAAHCYKSRIQ 57 Query: 72 VTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPS 131 V LG HNI E +QF+ + I HP ++ K +NDIML++L K V + LPS Sbjct: 58 VRLGEHNINVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVALPS 117 Query: 132 NKAQVKPGQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVG 190 + A G C ++GWG T G LQ + + CE+ + +CVG Sbjct: 118 SCA--PAGTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKITDNM-VCVG 174 Query: 191 DPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNNGMP--PRACTKVSSFVHWIKKTM 244 E K S +GDSGGP+VCN QGIVS+G +P P TKV ++V WI+ T+ Sbjct: 175 FLEGGKDSCQGDSGGPVVCNGELQGIVSWGYGCALPDNPGVYTKVCNYVDWIQDTI 230 >4AN7-A nrPDB Length = 231 Score = 325 bits (833), Expect = 1e-89, Method: Composition-based stats. Identities = 89/235 (37%), Positives = 120/235 (51%), Gaps = 10/235 (4%) Query: 13 LPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINV 72 P D +I+GG+ +S PY L CGG LI +V++AAHC+ S I V Sbjct: 1 FPTDDDDKIVGGYTCAANSIPYQVSL----NSGSHFCGGSLINSQWVVSAAHCYKSRIQV 56 Query: 73 TLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSN 132 LG HNI E +QFI + I HP +N NDIML++L A V + LP + Sbjct: 57 RLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRS 116 Query: 133 KAQVKPGQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGD 191 A G C ++GWG T G + LQ +K V D C+S + +CVG Sbjct: 117 CA--AAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNM-ICVGF 173 Query: 192 PEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNNGM--PPRACTKVSSFVHWIKKTM 244 E K S +GDSGGP+VCN QGIVS+G P TKV ++V+WI++T+ Sbjct: 174 LEGGKDSCQGDSGGPVVCNGQLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQTI 228 >1EUF-A nrPDB Length = 227 Score = 324 bits (831), Expect = 2e-89, Method: Composition-based stats. Identities = 138/227 (60%), Positives = 165/227 (72%), Gaps = 1/227 (0%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 IIGGHEAKPHSRPYMA+L+ CGGFL+R+DFVLTAAHC GSSINVTLGAHNI Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLGSSINVTLGAHNIM 60 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 140 E+E TQQ IPV+RPIPHP YN + +NDIMLL+L RKA T V P+ LP + A+VKPG Sbjct: 61 ERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAEVKPGM 120 Query: 141 TCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFK 200 CSVAGWG+ + LQEV + VQ + KC + ++Y T ++C GDP +K SF Sbjct: 121 MCSVAGWGRLGVNMPSTDKLQEVDLEVQSEEKCIARFKNYIPFT-QICAGDPSKRKNSFS 179 Query: 201 GDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMKRY 247 GDSGGPLVCN VAQGIVSYGRN+G P T++SSF+ WI TM+RY Sbjct: 180 GDSGGPLVCNGVAQGIVSYGRNDGTTPDVYTRISSFLSWIHSTMRRY 226 >5C67-A nrPDB Length = 224 Score = 312 bits (801), Expect = 6e-86, Method: Composition-based stats. Identities = 81/227 (35%), Positives = 113/227 (49%), Gaps = 10/227 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 I+GG+ + +S PY L CGG LI + +V++AAHC+ + I V LG HNIK Sbjct: 1 IVGGYTCEENSLPYQVSL----NSGSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIK 56 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 140 E +QFI + I HP YN NDIML++L A V + LP+ G Sbjct: 57 VLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAP--PAAGT 114 Query: 141 TCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 199 C ++GWG T G + L+ + V +C++ CVG E K S Sbjct: 115 ECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKIT-NSMFCVGFLEGGKDSC 173 Query: 200 KGDSGGPLVCNKVAQGIVSYGRNNGMP--PRACTKVSSFVHWIKKTM 244 + D+GGP+VCN QG+VS+G P TKV ++V WIK T+ Sbjct: 174 QRDAGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTI 220 >4WWY-A nrPDB Length = 224 Score = 312 bits (801), Expect = 8e-86, Method: Composition-based stats. Identities = 86/227 (37%), Positives = 118/227 (51%), Gaps = 10/227 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 I+GG+ + +S PY L CGG LI + +V++A HC+ S I V LG HNI+ Sbjct: 1 IVGGYNCEENSVPYQVSL----NSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIE 56 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 140 E +QFI + I HP Y+ K +NDIML++L +A V + LP+ G Sbjct: 57 VLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLPTAP--PATGT 114 Query: 141 TCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 199 C ++GWG TA G + LQ + V KCE+ S + CVG E K S Sbjct: 115 KCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNM-FCVGFLEGGKDSC 173 Query: 200 KGDSGGPLVCNKVAQGIVSYGRNNGM--PPRACTKVSSFVHWIKKTM 244 + DSGGP+VCN QG+VS+G P TKV ++V WIK T+ Sbjct: 174 QRDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTI 220 >1A0J-A nrPDB Length = 223 Score = 312 bits (799), Expect = 1e-85, Method: Composition-based stats. Identities = 87/227 (38%), Positives = 118/227 (51%), Gaps = 10/227 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 I+GG+E + +S Y A L CGG LI +V++AAHC+ S I V LG HNI Sbjct: 1 IVGGYECRKNSASYQASLQ----SGYHFCGGSLISSTWVVSAAHCYKSRIQVRLGEHNIA 56 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 140 E T+QFI + I HP+YN +N NDIML++L + A V + LPS+ A G Sbjct: 57 VNEGTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALPSSCAS--SGT 114 Query: 141 TCSVAGWGQTA-PLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 199 C V+GWG + + TL+ + + + C S S + C G E K S Sbjct: 115 RCLVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQITSNM-FCAGFMEGGKDSC 173 Query: 200 KGDSGGPLVCNKVAQGIVSYGRNNGM--PPRACTKVSSFVHWIKKTM 244 +GDSGGP+VCN QG+VS+G P TKV ++ WI TM Sbjct: 174 QGDSGGPVVCNGQLQGVVSWGYGCAQRNKPGVYTKVCNYRSWISSTM 220 >3TK9-A nrPDB Length = 226 Score = 305 bits (782), Expect = 1e-83, Method: Composition-based stats. Identities = 161/226 (71%), Positives = 180/226 (79%), Gaps = 1/226 (0%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 IIGGHEAKPHSRPYMA++ +KS KRCGG L+R DFVLTAAHC GSSINVTLGAHNIK Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQGSSINVTLGAHNIK 60 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 140 EQE TQQFIPVKRPIPHPAYNPKNFSN+IMLLQLERKAK T AV+PLRLPS+KAQVKPGQ Sbjct: 61 EQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQVKPGQ 120 Query: 141 TCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFK 200 CSVAGWG + + + TLQEV +TVQ+D +CE Y E+CVGDP+ +T FK Sbjct: 121 LCSVAGWGYVS-MSTLATTLQEVLLTVQKDCQCERLFHGNYSRATEICVGDPKKTQTGFK 179 Query: 201 GDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMKR 246 GDSGGPLVC VAQGI+SYG G PP KVS F+ WIK+TMKR Sbjct: 180 GDSGGPLVCKDVAQGILSYGNKKGTPPGVYIKVSHFLPWIKRTMKR 225 >3G01-A nrPDB Length = 227 Score = 300 bits (770), Expect = 3e-82, Method: Composition-based stats. Identities = 139/226 (61%), Positives = 163/226 (72%), Gaps = 1/226 (0%) Query: 21 IIGGHEAKPHSRPYMAYL-MIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNI 79 IIGG+E PHSRPYMAY + CGGFL+RD FVLTAAHC G S+ VTLGAHNI Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHCKGRSMTVTLGAHNI 60 Query: 80 KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 K +E TQQ IPV + IPHP YNP + SNDIMLL+L R AKRTRAV+PL LP A VKPG Sbjct: 61 KAKEETQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNAHVKPG 120 Query: 140 QTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 199 C VAGWG+ P G+ TL EVK+TVQ+D+ CES + Y+ E+CVGD +IK SF Sbjct: 121 DECYVAGWGKVTPDGEFPKTLHEVKLTVQKDQVCESQFQSSYNRANEICVGDSKIKGASF 180 Query: 200 KGDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMK 245 +GDSGGPLVC + A GIVSYG+ +G P+ T+V SFV WIKKTMK Sbjct: 181 RGDSGGPLVCKRAAAGIVSYGQTDGSAPQVFTRVLSFVSWIKKTMK 226 >1NN6-A nrPDB Length = 228 Score = 299 bits (767), Expect = 7e-82, Method: Composition-based stats. Identities = 120/228 (52%), Positives = 150/228 (65%), Gaps = 3/228 (1%) Query: 19 GEIIGGHEAKPHSRPYMAYL-MIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAH 77 GEIIGG E KPHSRPYMAYL ++ K CGGFLIR +FVLTAAHC G SI VTLGAH Sbjct: 1 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAH 60 Query: 78 NIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVK 137 NI E+E T Q + V + HP YN +DIMLL+L+ KA T AV L PS V Sbjct: 61 NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVP 120 Query: 138 PGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKT 197 PG+ C VAGWG+T L S TLQEVK+ + + + C +D ++LCVG+P K+ Sbjct: 121 PGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQAC--SHFRDFDHNLQLCVGNPRKTKS 178 Query: 198 SFKGDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMK 245 +FKGDSGGPL+C VAQGIVSYGR++ PP T++S + WI + ++ Sbjct: 179 AFKGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQ 226 >2TLD-E nrPDB Length = 220 Score = 297 bits (760), Expect = 4e-81, Method: Composition-based stats. Identities = 82/226 (36%), Positives = 116/226 (51%), Gaps = 11/226 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 I+GG+ ++ PY L CGG LI +V++AAHC+ S I V LG NI Sbjct: 1 IVGGYTCGANTVPYQVSL----NSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNIN 56 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 140 E +QFI + I HP+YN +NDIML++L+ A V + LP++ A G Sbjct: 57 VVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCAS--AGT 114 Query: 141 TCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 199 C ++GWG T G + L+ +K + D C+S S + C G S Sbjct: 115 QCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNM-FCAGLEGG--DSC 171 Query: 200 KGDSGGPLVCNKVAQGIVSYGRNNGM-PPRACTKVSSFVHWIKKTM 244 +GDSGGP+VC+ QGIVS+G P TKV ++V WIK+T+ Sbjct: 172 QGDSGGPVVCSGKLQGIVSWGSGCAKNKPGVYTKVCNYVSWIKQTI 217 >5TJX-A nrPDB Length = 263 Score = 294 bits (753), Expect = 3e-80, Method: Composition-based stats. Identities = 68/237 (28%), Positives = 104/237 (43%), Gaps = 11/237 (4%) Query: 15 RADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG-----SS 69 + I+GG E+ P+ L + CGG LI +VLTAAHC+ Sbjct: 10 TKTSTRIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDV 69 Query: 70 INVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRL 129 + G + + F +K I H Y ++DI L++L+ + T +P+ L Sbjct: 70 WRIYSGILELSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLEYTEFQKPISL 129 Query: 130 PSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCV 189 PS C V GWG + G+ + LQ+V + + + +C+ + Y + +C Sbjct: 130 PSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCA 189 Query: 190 GDPEIKKTSFKGDSGGPLVCN----KVAQGIVSYGRNNGM--PPRACTKVSSFVHWI 240 G E K + KGDSGGPLVC GI S+G P TKV+ ++ WI Sbjct: 190 GYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 246 >6I44-A nrPDB Length = 627 Score = 293 bits (751), Expect = 4e-80, Method: Composition-based stats. Identities = 67/237 (28%), Positives = 105/237 (44%), Gaps = 11/237 (4%) Query: 15 RADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG-----SS 69 + I+GG ++ P+ L + CGG LI +VLTAAHC+ Sbjct: 374 TKTSTRIVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDV 433 Query: 70 INVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRL 129 + G + + F +K I H Y ++DI L++L+ + T +P+ L Sbjct: 434 WRIYSGILQLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLQYTEFQKPICL 493 Query: 130 PSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCV 189 PS C V GWG +A G+ + LQ+V + + + +C+ + Y + +C Sbjct: 494 PSKGDTSTIYTNCWVTGWGFSAEAGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCA 553 Query: 190 GDPEIKKTSFKGDSGGPLVCN----KVAQGIVSYGRNNGM--PPRACTKVSSFVHWI 240 G E K + KGD+GGPLVC GI S+G P TKV+ ++ WI Sbjct: 554 GYKEGGKDACKGDAGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 610 >1FXY-A nrPDB Length = 228 Score = 293 bits (750), Expect = 5e-80, Method: Composition-based stats. Identities = 75/229 (32%), Positives = 114/229 (49%), Gaps = 10/229 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW--GSSINVTLGAHN 78 I+GG+ K P+ A L+ ++++ CGG ++ + ++LTAAHC V +G N Sbjct: 1 IVGGYNCKDGEVPWQALLI--NEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRN 58 Query: 79 IKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKP 138 +++E + V+ I H + + + DI +L+L+ V P LP+ Sbjct: 59 TEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLPTAP--PAT 116 Query: 139 GQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKT 197 G C ++GWG TA G + LQ + V KCE+ S + CVG E K Sbjct: 117 GTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNM-FCVGFLEGGKD 175 Query: 198 SFKGDSGGPLVCNKVAQGIVSYGRNNGM--PPRACTKVSSFVHWIKKTM 244 S +GDSGGP+VCN QG+VS+G P TKV ++V WIK T+ Sbjct: 176 SCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTI 224 >5GVT-A nrPDB Length = 250 Score = 292 bits (748), Expect = 1e-79, Method: Composition-based stats. Identities = 68/231 (29%), Positives = 98/231 (42%), Gaps = 11/231 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG-----SSINVTLG 75 I+GG A P+ L + CGG +I +VLTAAHC+ + G Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 76 AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ 135 ++ E +K I H Y + DI L++L+ T +P+ LPS Sbjct: 61 ILSLSEITKETPSSRIKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSKADT 120 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIK 195 C V GWG T G+ + LQ+ + + + +C+ R Y + +C G E Sbjct: 121 NTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYRDYVINKQMICAGYKEGG 180 Query: 196 KTSFKGDSGGPLVCN----KVAQGIVSYGRNNGMP--PRACTKVSSFVHWI 240 + KGDSGGPLVC GI S+G P TKVS ++ WI Sbjct: 181 TDACKGDSGGPLVCKHSGRWQLVGITSWGEGCARKDQPGVYTKVSEYMDWI 231 >1SGF-G nrPDB Length = 237 Score = 289 bits (741), Expect = 6e-79, Method: Composition-based stats. Identities = 83/241 (34%), Positives = 129/241 (53%), Gaps = 21/241 (8%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 I+GG + + +S+P+ + + Q CGG L+ ++VLTAAHC+ + V LG +N+ Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQ---YLCGGVLLDPNWVLTAAHCYDDNYKVWLGKNNLF 57 Query: 81 EQEPTQQFIPVKRPIPHPAYNPK-----------NFSNDIMLLQLERKAKRTRAVQPLRL 129 + EP+ Q V + IPHP +N ++SND+MLL+L + A T V+P+ L Sbjct: 58 KDEPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPITL 117 Query: 130 PSNKAQVKPGQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELC 188 P+ + ++ G TC +GWG P + + L V + + + C + LC Sbjct: 118 PTEEPKL--GSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIEKVTDAM-LC 174 Query: 189 VGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGR-NNGMP--PRACTKVSSFVHWIKKTMK 245 G+ + K + KGDSGGPL+C+ V QGI S+G G P P TK++ F WIK TM Sbjct: 175 AGEMDGGKDTCKGDSGGPLICDGVLQGITSWGHTPCGEPDMPGVYTKLNKFTSWIKDTMA 234 Query: 246 R 246 + Sbjct: 235 K 235 >2EEK-A nrPDB Length = 220 Score = 289 bits (740), Expect = 9e-79, Method: Composition-based stats. Identities = 78/226 (34%), Positives = 114/226 (50%), Gaps = 9/226 (3%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 I+GG+E HS+ + L CGG L+ D+V++AAHC+ S + V LG H+I+ Sbjct: 1 IVGGYECTKHSQAHQVSL----NSGYHFCGGSLVSKDWVVSAAHCYKSVLRVRLGEHHIR 56 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 140 E T+Q+I I HP Y+ N +NDIML++L + A + V + LP+ A Sbjct: 57 VNEGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPTECA--ADAT 114 Query: 141 TCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFK 200 C+V+GWG T LQ + + + C + ++ C G E K S + Sbjct: 115 MCTVSGWGNTMSSVADGDKLQCLSLPILSHADCANSYPGMITQSM-FCAGYLEGGKDSCQ 173 Query: 201 GDSGGPLVCNKVAQGIVSYGRNNGM--PPRACTKVSSFVHWIKKTM 244 GDSGGP+VCN V QG+VS+G P KV W++ TM Sbjct: 174 GDSGGPVVCNGVLQGVVSWGYGCAERDHPGVYAKVCVLSGWVRDTM 219 >4NFE-A nrPDB Length = 237 Score = 287 bits (734), Expect = 4e-78, Method: Composition-based stats. Identities = 87/239 (36%), Positives = 116/239 (48%), Gaps = 21/239 (8%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 I+GG E + HS+P+ + CGG L+ +VLTAAHC + V LG HN+ Sbjct: 1 IVGGWECEKHSQPWQVAVY---SHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 57 Query: 81 EQEPTQQFIPVKRPIPHPAYN-----------PKNFSNDIMLLQLERKAKRTRAVQPLRL 129 E E T Q +PV PHP YN ++ S+D+MLL+L AK T V+ L L Sbjct: 58 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 117 Query: 130 PSNKAQVKPGQTCSVAGWGQTAPLGKH-SHTLQEVKMTVQEDRKCESDLRHYYDSTIELC 188 P+ + + G TC +GWG P +LQ V + + + C LC Sbjct: 118 PTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVT-EFMLC 174 Query: 189 VGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYG-RNNGMP--PRACTKVSSFVHWIKKTM 244 G K + GDSGGPLVCN V QGI S+G +P P TKV + WIK T+ Sbjct: 175 AGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 233 >1KYN-A nrPDB Length = 235 Score = 285 bits (729), Expect = 2e-77, Method: Composition-based stats. Identities = 126/227 (55%), Positives = 165/227 (72%), Gaps = 2/227 (0%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 IIGG E++PHSRPYMAYL I RCGGFL+R+DFVLTAAHCWGS+INVTLGAHNI+ Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQ 60 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 140 +E TQQ I +R I HP YN + NDIMLLQL R+ +R R V P+ LP + ++PG Sbjct: 61 RRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGT 120 Query: 141 TCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFK 200 C+VAGWG+ + + + + TL+EV++ VQ DR+C YD ++CVGD +K +FK Sbjct: 121 LCTVAGWGRVS-MRRGTDTLREVQLRVQRDRQCLRIF-GSYDPRRQICVGDRRERKAAFK 178 Query: 201 GDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMKRY 247 GDSGGPL+CN VA GIVSYG+++G+PP T+VSSF+ WI+ TM+ + Sbjct: 179 GDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSF 225 >2F83-A nrPDB Length = 625 Score = 283 bits (726), Expect = 3e-77, Method: Composition-based stats. Identities = 70/232 (30%), Positives = 99/232 (42%), Gaps = 11/232 (4%) Query: 20 EIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW-----GSSINVTL 74 I+GG + P+ L CGG +I + ++LTAAHC+ + V Sbjct: 387 RIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYS 446 Query: 75 GAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKA 134 G N E + F V+ I H Y DI LL+LE T + +P+ LPS Sbjct: 447 GILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGD 506 Query: 135 QVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEI 194 + C V GWG K +TLQ+ K+ + + +C+ R + + +C G E Sbjct: 507 RNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREG 566 Query: 195 KKTSFKGDSGGPLVCN----KVAQGIVSYGRNNGM--PPRACTKVSSFVHWI 240 K + KGDSGGPL C GI S+G P T V +V WI Sbjct: 567 GKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWI 618 >1SPJ-A nrPDB Length = 238 Score = 278 bits (712), Expect = 1e-75, Method: Composition-based stats. Identities = 86/242 (35%), Positives = 125/242 (51%), Gaps = 22/242 (9%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 I+GG E + HS+P+ A L S +CGG L+ +VLTAAHC + + LG HN+ Sbjct: 1 IVGGWECEQHSQPWQAALY---HFSTFQCGGILVHRQWVLTAAHCISDNYQLWLGRHNLF 57 Query: 81 EQEPTQQFIPVKRPIPHPAYN-----------PKNFSNDIMLLQLERKA-KRTRAVQPLR 128 + E T QF+ V PHP +N +++S+D+MLL+L A T AV+ + Sbjct: 58 DDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVE 117 Query: 129 LPSNKAQVKPGQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIEL 187 LP+ + +V G TC +GWG P LQ V + + + +C+ L Sbjct: 118 LPTEEPEV--GSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTD-FML 174 Query: 188 CVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGR-NNGMP--PRACTKVSSFVHWIKKTM 244 CVG E K + GDSGGPL+C+ V QG+ S+G G P P +V S+V WI+ T+ Sbjct: 175 CVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTI 234 Query: 245 KR 246 Sbjct: 235 AE 236 >3W94-A nrPDB Length = 235 Score = 278 bits (711), Expect = 2e-75, Method: Composition-based stats. Identities = 75/238 (31%), Positives = 109/238 (45%), Gaps = 16/238 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSIN------VTL 74 ++GG A+ + P+M L + CG LI D++LTAAHC L Sbjct: 1 VVGGVNAEKGAWPWMVSL---HWRGRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVL 57 Query: 75 GAHNIKE-QEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNK 133 G H Q V R I + YN + DI ++ L++ T V P+ L S Sbjct: 58 GLHAQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLASED 117 Query: 134 AQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPE 193 G+ C +AGWG+ A G LQE ++ + + +C+ L Y ++ LC G PE Sbjct: 118 QHFPAGRRCFIAGWGRDAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTSSMLCAGYPE 177 Query: 194 IKKTSFKGDSGGPLVC----NKVAQGIVSYGRNNGMP--PRACTKVSSFVHWIKKTMK 245 S +GDSGGPL+C G+ S+G G P P A +VS+F WI +T + Sbjct: 178 GGVDSCQGDSGGPLMCLEDARWTLIGVTSFGVGCGRPERPGAYARVSAFTSWIAETRR 235 >5UGG-A nrPDB Length = 251 Score = 277 bits (709), Expect = 3e-75, Method: Composition-based stats. Identities = 86/245 (35%), Positives = 113/245 (46%), Gaps = 21/245 (8%) Query: 14 PRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW-----GS 68 P+ G ++GG A PHS P+ L + + CGG LI ++VLTAAHC S Sbjct: 15 PKKCPGRVVGGCVAHPHSWPWQVSLRT--RFGMHFCGGTLISPEWVLTAAHCLEKSPRPS 72 Query: 69 SINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLR 128 S V LGAH EP Q I V R P DI LL+L A T V P Sbjct: 73 SYKVILGAHQEVNLEPHVQEIEVSRLFLEPT------RKDIALLKLSSPAVITDKVIPAC 126 Query: 129 LPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCES-DLRHYYDSTIEL 187 LPS V C + GWG+T + L+E ++ V E++ C + + + EL Sbjct: 127 LPSPNYVVADRTECFITGWGETQGT-FGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTEL 185 Query: 188 CVGDPEIKKTSFKGDSGGPLVC----NKVAQGIVSYGRNNGMP--PRACTKVSSFVHWIK 241 C G S +GDSGGPLVC + QG+ S+G P P +VS FV WI+ Sbjct: 186 CAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIE 245 Query: 242 KTMKR 246 M+ Sbjct: 246 GVMRN 250 >4DUR-A nrPDB Length = 791 Score = 277 bits (709), Expect = 3e-75, Method: Composition-based stats. Identities = 86/245 (35%), Positives = 113/245 (46%), Gaps = 21/245 (8%) Query: 14 PRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW-----GS 68 P+ G ++GG A PHS P+ L + + CGG LI ++VLTAAHC S Sbjct: 555 PKKCPGRVVGGCVAHPHSWPWQVSLRT--RFGMHFCGGTLISPEWVLTAAHCLEKSPRPS 612 Query: 69 SINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLR 128 S V LGAH EP Q I V R P DI LL+L A T V P Sbjct: 613 SYKVILGAHQEVNLEPHVQEIEVSRLFLEPT------RKDIALLKLSSPAVITDKVIPAC 666 Query: 129 LPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCES-DLRHYYDSTIEL 187 LPS V C + GWG+T + L+E ++ V E++ C + + + EL Sbjct: 667 LPSPNYVVADRTECFITGWGETQGT-FGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTEL 725 Query: 188 CVGDPEIKKTSFKGDSGGPLVC----NKVAQGIVSYGRNNGMP--PRACTKVSSFVHWIK 241 C G S +GDSGGPLVC + QG+ S+G P P +VS FV WI+ Sbjct: 726 CAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIE 785 Query: 242 KTMKR 246 M+ Sbjct: 786 GVMRN 790 >3RP2-A nrPDB Length = 224 Score = 276 bits (707), Expect = 5e-75, Method: Composition-based stats. Identities = 109/225 (48%), Positives = 147/225 (65%), Gaps = 3/225 (1%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKR-CGGFLIRDDFVLTAAHCWGSSINVTLGAHNI 79 IIGG E+ PHSRPYMA+L I +K L+ CGGFLI FVLTAAHC G I V LGAH++ Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCKGREITVILGAHDV 60 Query: 80 KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 +++E TQQ I V++ I H +YN +DIMLL+LE+K + T AV + LPS + PG Sbjct: 61 RKRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDFIHPG 120 Query: 140 QTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 199 C AGWG+T S+TL+EV++ + +++ C D R YY+ ++CVG P + +F Sbjct: 121 AMCWAAGWGKTGVRDPTSYTLREVELRIMDEKAC-VDYR-YYEYKFQVCVGSPTTLRAAF 178 Query: 200 KGDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTM 244 GDSGGPL+C VA GIVSYG + PP T+VS++V WI + Sbjct: 179 MGDSGGPLLCAGVAHGIVSYGHPDAKPPAIFTRVSTYVPWINAVI 223 >3T2N-A nrPDB Length = 372 Score = 275 bits (704), Expect = 1e-74, Method: Composition-based stats. Identities = 74/250 (29%), Positives = 107/250 (42%), Gaps = 24/250 (9%) Query: 19 GEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINV----TL 74 I+GG + P+ L CGG L+ D+VLTAAHC+ V + Sbjct: 116 DRIVGGRDTSLGRWPWQVSLRYD---GAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRV 172 Query: 75 GAHNIKEQEPTQQFIPVKRPIPHPAY------NPKNFSNDIMLLQLERKAKRTRAVQPLR 128 A + + P + V+ + H Y N + SNDI L+ L T +QP+ Sbjct: 173 FAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVC 232 Query: 129 LPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCE-SDLRHYYDSTIEL 187 LP+ + G+ C+V GWG T G+ + LQE ++ + + C +D Sbjct: 233 LPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMF 292 Query: 188 CVGDPEIKKTSFKGDSGGPLVCNKVAQ--------GIVSYGRNN--GMPPRACTKVSSFV 237 C G PE + +GDSGGP VC GIVS+G P TKVS F Sbjct: 293 CAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFR 352 Query: 238 HWIKKTMKRY 247 WI + +K + Sbjct: 353 EWIFQAIKTH 362 >5MS3-A nrPDB Length = 228 Score = 275 bits (704), Expect = 1e-74, Method: Composition-based stats. Identities = 84/231 (36%), Positives = 126/231 (54%), Gaps = 14/231 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 ++GGHE +PHS+P+ A L Q CGG L+ ++VLTAAHC V LG H+++ Sbjct: 1 VLGGHECQPHSQPWQAALF---QGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 57 Query: 81 EQEPTQQFIPVKRPIPHPAYNP---KNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVK 137 ++ +Q IPV + IPHP YN ++ ++D+MLLQL +A V+P+ L + + Sbjct: 58 NKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCT--Q 115 Query: 138 PGQTCSVAGWGQ-TAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKK 196 PGQ C+V+GWG T+P TL ++ + +KCE + +C G Sbjct: 116 PGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGM-VCAG-SSKGA 173 Query: 197 TSFKGDSGGPLVCNKVAQGIVSYGR-NNGM--PPRACTKVSSFVHWIKKTM 244 + +GDSGGPLVC+ QGI S+G G P T + ++ WIKK + Sbjct: 174 DTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 224 >4DGJ-A nrPDB Length = 235 Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats. Identities = 71/235 (30%), Positives = 108/235 (45%), Gaps = 16/235 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW------GSSINVTL 74 I+GG +AK + P++ L D+ CG L+ D++++AAHC S L Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDR---LLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAIL 57 Query: 75 GAHNIKEQEPTQQF-IPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNK 133 G H Q + + +P YN + NDI ++ LE K T +QP+ LP Sbjct: 58 GLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPEEN 117 Query: 134 AQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPE 193 PG+ CS+AGWG G + LQE + + + +C+ + Y + +C G E Sbjct: 118 QVFPPGRNCSIAGWGTVVYQGTTADILQEADVPLLSNERCQQQMPEYNITENMICAGYEE 177 Query: 194 IKKTSFKGDSGGPLVCN----KVAQGIVSYGRNNGMP--PRACTKVSSFVHWIKK 242 S +GDSGGPL+C G+ S+G +P P +VS F WI+ Sbjct: 178 GGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYECALPNRPGVYARVSRFTEWIQS 232 >1KIG-H nrPDB Length = 241 Score = 272 bits (697), Expect = 8e-74, Method: Composition-based stats. Identities = 66/236 (27%), Positives = 111/236 (47%), Gaps = 14/236 (5%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG--SSINVTLGAHN 78 I+GG + P+ A L+ ++++ CGG ++ + +VLTAAHC V +G N Sbjct: 1 IVGGRDCAEGECPWQALLV--NEENEGFCGGTILNEFYVLTAAHCLHQAKRFTVRVGDRN 58 Query: 79 IKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNK---AQ 135 +++E + V+ + H + + + DI +L+L+ + R V P LP A Sbjct: 59 TEQEEGNEMAHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAEAT 118 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIK 195 + +T V+G+G+T G+ S TL+ +++ + C+ + C G Sbjct: 119 LMTQKTGIVSGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNM-FCAGYDTQP 177 Query: 196 KTSFKGDSGGPLVCN----KVAQGIVSYGRNNGMPP--RACTKVSSFVHWIKKTMK 245 + + +GDSGGP V GIVS+G TKVS+F+ WI K MK Sbjct: 178 EDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKFGVYTKVSNFLKWIDKIMK 233 >1X7A-C nrPDB Length = 235 Score = 272 bits (697), Expect = 8e-74, Method: Composition-based stats. Identities = 81/238 (34%), Positives = 117/238 (49%), Gaps = 18/238 (7%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW--GSSINVTLGAHN 78 I+GG AKP P+ L + K CGG +I + +V+TAAHC G I V G +N Sbjct: 1 IVGGENAKPGQFPWQVLL---NGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVAGEYN 57 Query: 79 IKEQEPTQQFIPVKRPIPHPAYNP--KNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ- 135 +E EPT+Q V R IPH +YN +S+DI LL+L+ V P+ + + Sbjct: 58 TEETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEYTN 117 Query: 136 --VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPE 193 +K G V+GWG+ G+ + LQ +K+ + + C + S + C G E Sbjct: 118 IFLKFGS-GYVSGWGRVFNRGRSATILQYLKVPLVDRATCLRSTKFTIYSNM-FCAGFHE 175 Query: 194 IKKTSFKGDSGGPLVCN----KVAQGIVSYGRNNGMPP--RACTKVSSFVHWIKKTMK 245 K S +GDSGGP V GI+S+G + TKVS +V+WIK+ K Sbjct: 176 GGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAVKGKYGIYTKVSRYVNWIKEKTK 233 >1EKB-B nrPDB Length = 235 Score = 272 bits (697), Expect = 8e-74, Method: Composition-based stats. Identities = 69/235 (29%), Positives = 111/235 (47%), Gaps = 16/235 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW------GSSINVTL 74 I+GG +++ + P++ L DQ+ CG L+ D++++AAHC S L Sbjct: 1 IVGGSDSREGAWPWVVALYFDDQQ---VCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVL 57 Query: 75 GAHNIKE-QEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNK 133 G H P + + + + +P YN + +NDI ++ LE K T +QP+ LP Sbjct: 58 GLHMASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLPEEN 117 Query: 134 AQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPE 193 PG+ CS+AGWG G + LQE + + + KC+ + Y + +C G Sbjct: 118 QVFPPGRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQQMPEYNITENMVCAGYEA 177 Query: 194 IKKTSFKGDSGGPLVCN----KVAQGIVSYGRNNGMP--PRACTKVSSFVHWIKK 242 S +GDSGGPL+C + G+ S+G +P P +V F WI+ Sbjct: 178 GGVDSCQGDSGGPLMCQENNRWLLAGVTSFGYQCALPNRPGVYARVPRFTEWIQS 232 >1NPM-A nrPDB Length = 225 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 86/231 (37%), Positives = 126/231 (54%), Gaps = 14/231 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 I+ G E PHS+P+ A L Q CGG L+ D +VLTAAHC +V LG H+++ Sbjct: 1 ILEGRECIPHSQPWQAALF---QGERLICGGVLVGDRWVLTAAHCKKQKYSVRLGDHSLQ 57 Query: 81 EQEPTQQFIPVKRPIPHPAY---NPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVK 137 ++ +Q I V + I HP Y NP++ S+DIML++L+ A V+P++L + +V Sbjct: 58 SRDQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQLANLCPKV- 116 Query: 138 PGQTCSVAGWGQ-TAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKK 196 GQ C ++GWG T+P +TL ++ + KCE + +C G Sbjct: 117 -GQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKITEGM-VCAG-SSNGA 173 Query: 197 TSFKGDSGGPLVCNKVAQGIVSYGR-NNGMP--PRACTKVSSFVHWIKKTM 244 + +GDSGGPLVC+ + QGI S+G G P P TK+ + WIKKTM Sbjct: 174 DTCQGDSGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTM 224 >6AOD-C nrPDB Length = 245 Score = 272 bits (695), Expect = 1e-73, Method: Composition-based stats. Identities = 68/231 (29%), Positives = 99/231 (42%), Gaps = 11/231 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW-----GSSINVTLG 75 I+GG + P+ L CGG +I + ++LTAAHC+ + V G Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 76 AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ 135 E + F V+ I H Y DI LL+LE + T + +P+ LPS + Sbjct: 61 ILQQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKGDR 120 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIK 195 C V GWG K +TLQ+ K+ + + +C+ R + + +C G E Sbjct: 121 NVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGG 180 Query: 196 KTSFKGDSGGPLVCN----KVAQGIVSYGRNNGM--PPRACTKVSSFVHWI 240 K + KGD+GGPL C GI S+G P T V +V WI Sbjct: 181 KDACKGDAGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWI 231 >3QUM-P nrPDB Length = 237 Score = 272 bits (695), Expect = 1e-73, Method: Composition-based stats. Identities = 82/239 (34%), Positives = 114/239 (47%), Gaps = 21/239 (8%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 I+GG E + HS+P+ + + CGG L+ +VLTAAHC + + LG H++ Sbjct: 1 IVGGWECEKHSQPWQVLVA---SRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 57 Query: 81 EQEPTQQFIPVKRPIPHPAYN-----------PKNFSNDIMLLQLERKAKRTRAVQPLRL 129 E T Q V PHP Y+ + S+D+MLL+L A+ T AV+ + L Sbjct: 58 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 117 Query: 130 PSNKAQVKPGQTCSVAGWGQTAPLGK-HSHTLQEVKMTVQEDRKCESDLRHYYDSTIELC 188 P+ + + G TC +GWG P LQ V + V + C LC Sbjct: 118 PTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTK-FMLC 174 Query: 189 VGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYG-RNNGMP--PRACTKVSSFVHWIKKTM 244 G K++ GDSGGPLVCN V QGI S+G +P P TKV + WIK T+ Sbjct: 175 AGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 233 >3K65-B nrPDB Length = 308 Score = 271 bits (693), Expect = 2e-73, Method: Composition-based stats. Identities = 68/268 (25%), Positives = 105/268 (39%), Gaps = 34/268 (12%) Query: 12 LLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-----W 66 LL G I+ G +A+ P+ L + L CG LI D +VLTAAHC W Sbjct: 41 LLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPW 99 Query: 67 GSSIN-----VTLGAHNIKEQEPTQQFIPV-KRPIPHPAYNP-KNFSNDIMLLQLERKAK 119 + V +G H+ E + I + ++ HP YN +N DI L++L++ Sbjct: 100 DKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVA 159 Query: 120 RTRAVQPLRLPSNKAQ---VKPGQTCSVAGWGQTAPLGK------HSHTLQEVKMTVQED 170 + + P+ LP + ++ G V GWG LQ V + + E Sbjct: 160 FSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVER 219 Query: 171 RKCESDLRHYYDSTIELCVGD---PEIKKTSFKGDSGGPLVCN------KVAQGIVSYGR 221 C+ R + C G + + +GD+GGP V GIVS+G Sbjct: 220 PVCKDSTRIRITDNM-FCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIVSWGE 278 Query: 222 NNGM--PPRACTKVSSFVHWIKKTMKRY 247 T V WI+K + ++ Sbjct: 279 GCDRDGKYGFYTHVFRLKKWIQKVIDQF 306 >3LC3-A nrPDB Length = 235 Score = 270 bits (692), Expect = 3e-73, Method: Composition-based stats. Identities = 75/238 (31%), Positives = 117/238 (49%), Gaps = 18/238 (7%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGS--SINVTLGAHN 78 ++GG +AKP P+ L + K CGG ++ + +++TAAHC + I V G HN Sbjct: 1 VVGGEDAKPGQFPWQVVL---NGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHN 57 Query: 79 IKEQEPTQQFIPVKRPIPHPAYNP--KNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ- 135 I+E E T+Q V R IPH YN +++DI LL+L+ V P+ + + Sbjct: 58 IEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTN 117 Query: 136 --VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPE 193 +K G V+GWG+ G+ + LQ +++ + + C + + + C G E Sbjct: 118 IFLKFGS-GYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNM-FCAGFHE 175 Query: 194 IKKTSFKGDSGGPLVCN----KVAQGIVSYGRNNGMPP--RACTKVSSFVHWIKKTMK 245 + S +GDSGGP V GI+S+G M TKVS +V+WIK+ K Sbjct: 176 GGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTK 233 >1TON-A nrPDB Length = 235 Score = 270 bits (692), Expect = 3e-73, Method: Composition-based stats. Identities = 85/241 (35%), Positives = 123/241 (51%), Gaps = 23/241 (9%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 I+GG++ + +S+P+ ++ + CGG LI +V+TAAHC+ ++ V LG +N+ Sbjct: 1 IVGGYKCEKNSQPWQVAVI-----NEYLCGGVLIDPSWVITAAHCYSNNYQVLLGRNNLF 55 Query: 81 EQEPTQQFIPVKRPIPHPAYNP-----------KNFSNDIMLLQLERKAKRTRAVQPLRL 129 + EP Q V++ HP Y P + SND+MLL L A T V+ + L Sbjct: 56 KDEPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVIDL 115 Query: 130 PSNKAQVKPGQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELC 188 P+ + +V G TC +GWG T P SH LQ V + + + KC + + LC Sbjct: 116 PTKEPKV--GSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTD-VMLC 172 Query: 189 VGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGR-NNGMP--PRACTKVSSFVHWIKKTMK 245 G+ E K + GDSGGPL+C+ V QGI S G P P K+ F WIKK MK Sbjct: 173 AGEMEGGKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKVMK 232 Query: 246 R 246 Sbjct: 233 E 233 >3NXP-A nrPDB Length = 424 Score = 270 bits (691), Expect = 4e-73, Method: Composition-based stats. Identities = 69/268 (25%), Positives = 105/268 (39%), Gaps = 34/268 (12%) Query: 12 LLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-----W 66 LL G I+ G +A+ P+ L + L CG LI D +VLTAAHC W Sbjct: 157 LLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPW 215 Query: 67 GSSIN-----VTLGAHNIKEQEPTQQFIPV-KRPIPHPAYNP-KNFSNDIMLLQLERKAK 119 + V +G H+ E + I + ++ HP YN +N DI L++L++ Sbjct: 216 DKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVA 275 Query: 120 RTRAVQPLRLPSNKAQ---VKPGQTCSVAGWGQTAPLGK------HSHTLQEVKMTVQED 170 + + P+ LP + ++ G V GWG LQ V + + E Sbjct: 276 FSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVER 335 Query: 171 RKCESDLRHYYDSTIELCVGD---PEIKKTSFKGDSGGPLVCN------KVAQGIVSYGR 221 C+ R + C G + + +GDSGGP V GIVS+G Sbjct: 336 PVCKDSTRIRITDNM-FCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE 394 Query: 222 NNGM--PPRACTKVSSFVHWIKKTMKRY 247 T V WI+K + ++ Sbjct: 395 GCDRDGKYGFYTHVFRLKKWIQKVIDQF 422 >2RDL-A nrPDB Length = 226 Score = 270 bits (691), Expect = 4e-73, Method: Composition-based stats. Identities = 102/227 (44%), Positives = 139/227 (61%), Gaps = 3/227 (1%) Query: 21 IIGGHEAKPHSRPYMAYL-MIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNI 79 IIGG E +PH+RPYMAYL ++ + L C GFLIR +FV+TAAHC G SI V LGAHN Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAGRSITVLLGAHNK 60 Query: 80 KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 K +E T Q + V++ PHP Y+ + NDIMLL+L+ KA T V L + + + PG Sbjct: 61 KVKEDTWQKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPISAKSNSIPPG 120 Query: 140 QTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 199 + C GWG+T S TLQEVKM + + + C+ + +LCVG+P+ + + Sbjct: 121 RVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQACK--HFEDFHQEPQLCVGNPKKIRNVY 178 Query: 200 KGDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMKR 246 KGDSGGPL+C +AQGI SY N PP T++S + WI K ++ Sbjct: 179 KGDSGGPLLCAGIAQGIASYVLRNAKPPSVFTRISHYRPWINKILRE 225 >4GSO-A nrPDB Length = 232 Score = 270 bits (690), Expect = 5e-73, Method: Composition-based stats. Identities = 72/229 (31%), Positives = 106/229 (46%), Gaps = 12/229 (5%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 ++GG E + P++A+L CG LI ++V+TAAHC ++ + LG H+ K Sbjct: 1 VLGGDECDINEHPFLAFLY----SHGYFCGLTLINQEWVVTAAHCDSTNFQMQLGVHSKK 56 Query: 81 EQEPTQQFIPVKRPIPHPAYN-PKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 +Q K P N + DIML++L++ ++ + PL LPSN V G Sbjct: 57 VLNEDEQTRNPKEKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPSNPPSV--G 114 Query: 140 QTCSVAGWGQ-TAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTS 198 C + GWG T P + + + + C+ T LC G E K + Sbjct: 115 SVCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLPAKT-TLCAGVLEGGKDT 173 Query: 199 FKGDSGGPLVCNKVAQGIVSYG---RNNGMPPRACTKVSSFVHWIKKTM 244 GDSGGPL+CN QGIVSYG G P T V + WI++ + Sbjct: 174 CVGDSGGPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNI 222 >2PSX-A nrPDB Length = 227 Score = 269 bits (689), Expect = 6e-73, Method: Composition-based stats. Identities = 78/230 (33%), Positives = 122/230 (53%), Gaps = 11/230 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 II G + H++P+ A L++ + CG L+ ++LTAAHC V LG +++ Sbjct: 1 IINGSDCDMHTQPWQAALLLRPNQ--LYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 58 Query: 81 E-QEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 E QQ + IPHP Y+ SND+ML++L R+ + T+ V+P+ + S+ G Sbjct: 59 PVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS--AG 116 Query: 140 QTCSVAGWGQT-APLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTS 198 C V+GWG T +P LQ + ++V ++CE D T+ C GD + + S Sbjct: 117 TKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTM-FCAGD-KAGRDS 174 Query: 199 FKGDSGGPLVCNKVAQGIVSYGR-NNGMP--PRACTKVSSFVHWIKKTMK 245 +GDSGGP+VCN QG+VS+G P P T + F WI++T++ Sbjct: 175 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 224 >3BSQ-A nrPDB Length = 227 Score = 269 bits (688), Expect = 8e-73, Method: Composition-based stats. Identities = 81/229 (35%), Positives = 116/229 (50%), Gaps = 12/229 (5%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 II G S P+ L+ +Q CGG L+ + +VLTAAHC + V LG+ + Sbjct: 1 IIDGAPCARGSHPWQVALLSGNQ---LHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG 57 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 140 ++ Q I + HP Y+ + ND+ML++L +A+ + V+ +RLPS PG Sbjct: 58 DRR--AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPGT 113 Query: 141 TCSVAGWGQT-APLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 199 TC+V+GWG T +P L V + + + C + + LC G P+ KK + Sbjct: 114 TCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLE-NSMLCAGIPDSKKNAC 172 Query: 200 KGDSGGPLVCNKVAQGIVSYGR-NNGMP--PRACTKVSSFVHWIKKTMK 245 GDSGGPLVC QG+VS+G G P P T+V F WI TMK Sbjct: 173 NGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 221 >4NZQ-A nrPDB Length = 557 Score = 269 bits (688), Expect = 9e-73, Method: Composition-based stats. Identities = 69/268 (25%), Positives = 105/268 (39%), Gaps = 34/268 (12%) Query: 12 LLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-----W 66 LL G I+ G +A+ P+ L + L CG LI D +VLTAAHC W Sbjct: 290 LLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPW 348 Query: 67 GSSIN-----VTLGAHNIKEQEPTQQFIPV-KRPIPHPAYNP-KNFSNDIMLLQLERKAK 119 + V +G H+ E + I + ++ HP YN +N DI L++L++ Sbjct: 349 DKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVA 408 Query: 120 RTRAVQPLRLPSNKAQ---VKPGQTCSVAGWGQTAPLGK------HSHTLQEVKMTVQED 170 + + P+ LP + ++ G V GWG LQ V + + E Sbjct: 409 FSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVER 468 Query: 171 RKCESDLRHYYDSTIELCVGD---PEIKKTSFKGDSGGPLVCN------KVAQGIVSYGR 221 C+ R + C G + + +GDSGGP V GIVS+G Sbjct: 469 PVCKDSTRIRITDNM-FCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE 527 Query: 222 NNGM--PPRACTKVSSFVHWIKKTMKRY 247 T V WI+K + ++ Sbjct: 528 GCDRDGKYGFYTHVFRLKKWIQKVIDQF 555 >1AO5-A nrPDB Length = 237 Score = 269 bits (688), Expect = 9e-73, Method: Composition-based stats. Identities = 78/241 (32%), Positives = 120/241 (49%), Gaps = 21/241 (8%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 ++GG + +S+P+ + + CGG L+ ++VLTAAHC+ V LG + + Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQKE---HICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLF 57 Query: 81 EQEPTQQFIPVKRPIPHPAYN-----------PKNFSNDIMLLQLERKAKRTRAVQPLRL 129 ++EP+ Q V + PHP +N +FS+D+MLL+L + A T V+P+ L Sbjct: 58 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPIAL 117 Query: 130 PSNKAQVKPGQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELC 188 P+ + KPG C +GWG P + LQ V +T+ + C + LC Sbjct: 118 PTKE--PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTD-VMLC 174 Query: 189 VGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYG-RNNGMP--PRACTKVSSFVHWIKKTMK 245 G+ K + + DSGGPL+C+ + QG SYG G P P T + F WIK TM Sbjct: 175 AGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMM 234 Query: 246 R 246 + Sbjct: 235 K 235 >1BRU-P nrPDB Length = 241 Score = 269 bits (688), Expect = 9e-73, Method: Composition-based stats. Identities = 74/241 (30%), Positives = 108/241 (44%), Gaps = 16/241 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMI-WDQKSLKRCGGFLIRDDFVLTAAHCWGSS--INVTLGAH 77 ++GG +A+P+S P+ L + CGG L+ +VLTAAHC SS V LG H Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRH 60 Query: 78 NIKEQEPTQQFIPVKRPIPHPAYNPKNFSN--DIMLLQLERKAKRTRAVQPLRLPSNKAQ 135 ++ EP + V + + H +N SN DI LL+L T +Q LP+ Sbjct: 61 SLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAGTI 120 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESD-LRHYYDSTIELCVGDPEI 194 + C V GWG+ G LQ+ ++ V + C T +C G + Sbjct: 121 LPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAGG-DG 179 Query: 195 KKTSFKGDSGGPLVCNK-----VAQGIVSYGRNNGM----PPRACTKVSSFVHWIKKTMK 245 +S GDSGGPL C GIVS+G + G P T+VS+++ WI + Sbjct: 180 IISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINSVIA 239 Query: 246 R 246 Sbjct: 240 N 240 >1P57-B nrPDB Length = 255 Score = 268 bits (687), Expect = 1e-72, Method: Composition-based stats. Identities = 74/248 (29%), Positives = 107/248 (43%), Gaps = 24/248 (9%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINV----TLGA 76 I+GG + P+ L CGG L+ D+VLTAAHC+ V + A Sbjct: 1 IVGGRDTSLGRWPWQVSLRYD---GAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFA 57 Query: 77 HNIKEQEPTQQFIPVKRPIPHPAY------NPKNFSNDIMLLQLERKAKRTRAVQPLRLP 130 + + P + V+ + H Y N + SNDI L+ L T +QP+ LP Sbjct: 58 GAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLP 117 Query: 131 SNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCE-SDLRHYYDSTIELCV 189 + + G+ C+V GWG T G+ + LQE ++ + + C +D C Sbjct: 118 AAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCA 177 Query: 190 GDPEIKKTSFKGDSGGPLVCNKVAQ--------GIVSYGRNN--GMPPRACTKVSSFVHW 239 G PE + +GDSGGP VC GIVS+G P TKVS F W Sbjct: 178 GYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREW 237 Query: 240 IKKTMKRY 247 I + +K + Sbjct: 238 IFQAIKTH 245 >4MPW-A nrPDB Length = 245 Score = 267 bits (684), Expect = 2e-72, Method: Composition-based stats. Identities = 75/248 (30%), Positives = 112/248 (45%), Gaps = 27/248 (10%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG------SSINVTL 74 I+GG EA P+ L + + CGG LI +VLTAAHC G +++ V L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 60 Query: 75 GAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKA 134 ++ Q+ Q +PV R I HP + DI LL+LE K + V + LP Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASE 117 Query: 135 QVKPGQTCSVAGWGQTAPLGKH--SHTLQEVKMTVQEDRKCESDLR--------HYYDST 184 PG C V GWG + L++VK+ + E+ C++ Sbjct: 118 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 177 Query: 185 IELCVGDPEIKKTSFKGDSGGPLVCN----KVAQGIVSYGRNNGMP--PRACTKVSSFVH 238 LC G+ ++ S +GDSGGPLVC + G+VS+G P P T+V+ ++ Sbjct: 178 DMLCAGN--TRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLD 235 Query: 239 WIKKTMKR 246 WI + + Sbjct: 236 WIHHYVPK 243 >5ZFH-A nrPDB Length = 224 Score = 267 bits (682), Expect = 5e-72, Method: Composition-based stats. Identities = 82/231 (35%), Positives = 121/231 (52%), Gaps = 12/231 (5%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 II G++ K S P+ L+ +Q CGG L+ +VLTAAHC V LG+ I Sbjct: 1 IIDGYKCKEGSHPWQVALLKGNQ---LHCGGVLVDKYWVLTAAHCKMGQYQVQLGSDKIG 57 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 140 +Q + Q I + HP Y+ K NDIML++L+ K + V+ ++LP + PG Sbjct: 58 DQ--SAQKIKATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLPEHCE--PPGT 113 Query: 141 TCSVAGWGQT-APLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 199 +C+V+GWG T +P L + + R+C+ + T+ LC G P+ K + Sbjct: 114 SCTVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKVYKDLLGKTM-LCAGIPDSKTNTC 172 Query: 200 KGDSGGPLVCNKVAQGIVSYG-RNNGMP--PRACTKVSSFVHWIKKTMKRY 247 GDSGGPLVCN QG+VS+G G P P T+V + W+ +TMK + Sbjct: 173 NGDSGGPLVCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETMKTH 223 >1MKW-K nrPDB Length = 308 Score = 266 bits (681), Expect = 6e-72, Method: Composition-based stats. Identities = 73/267 (27%), Positives = 105/267 (39%), Gaps = 34/267 (12%) Query: 12 LLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-----W 66 L G I+ G +A+ P+ L + L CG LI D +VLTAAHC W Sbjct: 41 LFESYIEGRIVEGQDAEVGLSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPW 99 Query: 67 GSSIN-----VTLGAHNIKEQEPTQQFIPV-KRPIPHPAYNP-KNFSNDIMLLQLERKAK 119 + V +G H+ E + I + + HP YN +N DI LL+L+R + Sbjct: 100 DKNFTVDDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIE 159 Query: 120 RTRAVQPLRLPSNKAQVK---PGQTCSVAGWGQ------TAPLGKHSHTLQEVKMTVQED 170 + + P+ LP + K G V GWG T+ LQ V + + E Sbjct: 160 LSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVER 219 Query: 171 RKCESDLRHYYDSTIELCVGD---PEIKKTSFKGDSGGPLVCN------KVAQGIVSYGR 221 C++ R + C G + + +GDSGGP V GIVS+G Sbjct: 220 PVCKASTRIRITDNM-FCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGE 278 Query: 222 NNGM--PPRACTKVSSFVHWIKKTMKR 246 T V WI+K + R Sbjct: 279 GCDRDGKYGFYTHVFRLKKWIQKVIDR 305 >2F91-A nrPDB Length = 237 Score = 266 bits (681), Expect = 6e-72, Method: Composition-based stats. Identities = 70/235 (29%), Positives = 99/235 (42%), Gaps = 16/235 (6%) Query: 21 IIGGHEAKPHSRPYMAYLM-IWDQKSLKRCGGFLIRDDFVLTAAHCW-------GSSINV 72 I+GG +A PY + S CG + +++ +TA HC S + + Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 73 TLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSN 132 G ++ E ++Q I V + I H ++ NDI LL+L V P+ LP Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALPEQ 120 Query: 133 KAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDP 192 V GWG T+ G LQ+V + + D C +D +C G P Sbjct: 121 GHTAT--GDVIVTGWGTTSEGGNTPDVLQKVTVPLVSDEDCRADYGADEILDSMICAGVP 178 Query: 193 EIKKTSFKGDSGGPLVCNKV----AQGIVSYGRNNGMP--PRACTKVSSFVHWIK 241 E K S +GDSGGPL + GIVS+G P P T+VS V WIK Sbjct: 179 EGGKDSCQGDSGGPLAASDTGSTYLAGIVSWGYGCARPGYPGVYTEVSYHVDWIK 233 >1FUJ-A nrPDB Length = 221 Score = 265 bits (677), Expect = 1e-71, Method: Composition-based stats. Identities = 88/232 (37%), Positives = 121/232 (52%), Gaps = 18/232 (7%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSS----INVTLGA 76 I+GGHEA+PHSRPYMA L + CGG LI FVLTAAHC +NV LGA Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 60 Query: 77 HNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQV 136 HN++ QEPTQQ V + Y+ +N NDI+L+QL A + +V ++LP V Sbjct: 61 HNVRTQEPTQQHFSVAQVFL-NNYDAENKLNDILLIQLSSPANLSASVATVQLPQQDQPV 119 Query: 137 KPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKK 196 G C GWG+ + LQE+ +TV ++ +C P K Sbjct: 120 PHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT----------FFCRPHNICTFVPRRKA 169 Query: 197 TSFKGDSGGPLVCNKVAQGIVS---YGRNNGMPPRACTKVSSFVHWIKKTMK 245 GDSGGPL+C+ + QGI S +G + P T+V+ +V WI+ T++ Sbjct: 170 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 221 >4H4F-A nrPDB Length = 249 Score = 265 bits (677), Expect = 2e-71, Method: Composition-based stats. Identities = 72/239 (30%), Positives = 110/239 (46%), Gaps = 15/239 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMI-WDQKSLKRCGGFLIRDDFVLTAAHCWGSS--INVTLGAH 77 ++GG +A+PHS P+ L + CGG LI +FVLTAAHC ++ V +G + Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 60 Query: 78 NIK-EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQV 136 N++ E E F+ V H +N NDI L++L + + +Q LP + + Sbjct: 61 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 120 Query: 137 KPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCES-DLRHYYDSTIELCVGDPEIK 195 C V GWG+ G + LQ+ V + C D + +C G + Sbjct: 121 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG-DGV 179 Query: 196 KTSFKGDSGGPLVCN-----KVAQGIVSYG--RNN--GMPPRACTKVSSFVHWIKKTMK 245 ++ GDSGGPL C GIVS+G R P T+VS+++ WI + M+ Sbjct: 180 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 238 >3E0N-B nrPDB Length = 271 Score = 265 bits (677), Expect = 2e-71, Method: Composition-based stats. Identities = 75/246 (30%), Positives = 111/246 (45%), Gaps = 23/246 (9%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGS-----SINVTLG 75 I GG A P+ + + + CGG L+ + +VL+AAHC+ S + V LG Sbjct: 1 ITGGSSAVAGQWPWQVSITY---EGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLG 57 Query: 76 AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ 135 AH + + +K IPHP+Y + DI LLQL R +R ++P+ LP+ +A Sbjct: 58 AHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQAS 117 Query: 136 VKPGQTCSVAGWGQTAPLGK--HSHTLQEVKMTVQEDRKCESDLR-------HYYDSTIE 186 G C+V GWG AP LQ++++ + C S ++ Sbjct: 118 FPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQEDM 177 Query: 187 LCVGDPEIKKTSFKGDSGGPLVCN----KVAQGIVSYGRNNGM--PPRACTKVSSFVHWI 240 +C G E K + +GDSGGPL C GIVS+G G P T SS+ WI Sbjct: 178 VCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWI 237 Query: 241 KKTMKR 246 + + Sbjct: 238 QSKVTE 243 >3DFJ-A nrPDB Length = 263 Score = 264 bits (676), Expect = 2e-71, Method: Composition-based stats. Identities = 74/246 (30%), Positives = 110/246 (44%), Gaps = 23/246 (9%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGS-----SINVTLG 75 I GG A P+ + + + CGG L+ + +VL+AAHC+ S + V LG Sbjct: 1 ITGGSSAVAGQWPWQVSITY---EGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLG 57 Query: 76 AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ 135 AH + + +K IPHP+Y + DI LLQL R +R ++P+ LP+ A Sbjct: 58 AHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAANAS 117 Query: 136 VKPGQTCSVAGWGQTAPLGK--HSHTLQEVKMTVQEDRKCESDLR-------HYYDSTIE 186 G C+V GWG AP LQ++++ + C + ++ Sbjct: 118 FPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFVQEDM 177 Query: 187 LCVGDPEIKKTSFKGDSGGPLVCN----KVAQGIVSYGRNNGM--PPRACTKVSSFVHWI 240 +C G E K + +GDSGGPL C GIVS+G G P T SS+ WI Sbjct: 178 VCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWI 237 Query: 241 KKTMKR 246 + + Sbjct: 238 QSKVTE 243 >1LTO-A nrPDB Length = 245 Score = 264 bits (676), Expect = 2e-71, Method: Composition-based stats. Identities = 75/248 (30%), Positives = 111/248 (44%), Gaps = 27/248 (10%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG------SSINVTL 74 I+GG EA P+ L + D+ + CGG LI +VLTAAHC G +++ V L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQL 60 Query: 75 GAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKA 134 ++ Q+ Q +PV R I HP + DI LL+LE + V + LP Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPASE 117 Query: 135 QVKPGQTCSVAGWGQTAPLGKH--SHTLQEVKMTVQEDRKCESDLR--------HYYDST 184 PG C V GWG L++VK+ + E+ C++ Sbjct: 118 TFPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIIRD 177 Query: 185 IELCVGDPEIKKTSFKGDSGGPLVCN----KVAQGIVSYGRNNGMP--PRACTKVSSFVH 238 LC G+ ++ S KGDSGGPLVC + G+VS+ P P T+V+ ++ Sbjct: 178 DMLCAGNS--QRDSCKGDSGGPLVCKVNGTWLQAGVVSWDEGCAQPNRPGIYTRVTYYLD 235 Query: 239 WIKKTMKR 246 WI + + Sbjct: 236 WIHHYVPK 243 >1SGF-A nrPDB Length = 240 Score = 264 bits (676), Expect = 2e-71, Method: Composition-based stats. Identities = 78/236 (33%), Positives = 125/236 (52%), Gaps = 22/236 (9%) Query: 26 EAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIKEQEPT 85 + + +S+P+ + +++ CGG L+ ++VLTAAHC+ V LG +N E EP+ Sbjct: 10 DCE-NSQPWHVAVYRFNKYQ---CGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPS 65 Query: 86 QQFIPVKRPIPHPAYN-----------PKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKA 134 Q V + IPHP +N ++SND+MLL+L + A T V+P+ LP+ + Sbjct: 66 DQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEP 125 Query: 135 QVKPGQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPE 193 ++ G TC +GWG T P+ K+ LQ V + + + C+ + LC G+ + Sbjct: 126 KL--GSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAM-LCAGEMD 182 Query: 194 IKKTSFKGDSGGPLVCNKVAQGIVSYG-RNNGMP--PRACTKVSSFVHWIKKTMKR 246 + + DSGGPL+C+ + QGI S+G G P P TK+ F WI++TM Sbjct: 183 GGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMAN 238 >1C5M-D nrPDB Length = 255 Score = 264 bits (676), Expect = 2e-71, Method: Composition-based stats. Identities = 63/237 (26%), Positives = 111/237 (46%), Gaps = 14/237 (5%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW--GSSINVTLGAHN 78 I+GG E K P+ A L+ ++++ CGG ++ + ++LTAAHC V +G N Sbjct: 1 IVGGQECKDGECPWQALLI--NEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRN 58 Query: 79 IKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNK---AQ 135 +++E + V+ I H + + + DI +L+L+ V P LP + Sbjct: 59 TEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAEST 118 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIK 195 + +T V+G+G+T G+ S L+ +++ + C+ + C G + Sbjct: 119 LMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNM-FCAGYDTKQ 177 Query: 196 KTSFKGDSGGPLVCN----KVAQGIVSYGRNNGMPP--RACTKVSSFVHWIKKTMKR 246 + + +GDSGGP V GIVS+G TKV++F+ WI ++MK Sbjct: 178 EDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT 234 >1FDP-A nrPDB Length = 235 Score = 264 bits (675), Expect = 3e-71, Method: Composition-based stats. Identities = 85/234 (36%), Positives = 121/234 (51%), Gaps = 13/234 (5%) Query: 19 GEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW----GSSINVTL 74 G I+GG EA+ H+RPYMA + + CGG L+ + +VL+AAHC + V L Sbjct: 6 GRILGGREAEAHARPYMASVQL---NGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLL 62 Query: 75 GAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKA 134 GAH++ + EP+++ V R +PHP P +D++LLQL KA AV+PL Sbjct: 63 GAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDR 122 Query: 135 QVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRH-YYDSTIELCVGDPE 193 V PG C VAGWG G+ +LQ V + V + C H + +C Sbjct: 123 DVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCA--ES 180 Query: 194 IKKTSFKGDSGGPLVCNKVAQGIVSYG---RNNGMPPRACTKVSSFVHWIKKTM 244 ++ S KGDSGGPLVC V +G+V+ G N P T+V+S+ WI + Sbjct: 181 NRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVL 234 >2AIQ-A nrPDB Length = 231 Score = 263 bits (674), Expect = 4e-71, Method: Composition-based stats. Identities = 70/229 (30%), Positives = 106/229 (46%), Gaps = 13/229 (5%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 +IGG E + ++A + + CGG LI ++VLTA HC ++ + LG HN+K Sbjct: 1 VIGGDECNINEHRFLALVYA----NGSLCGGTLINQEWVLTARHCDRGNMRIYLGMHNLK 56 Query: 81 EQEPTQ-QFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 + P ++ N + DIML++L R + + + PL LPSN V G Sbjct: 57 VLNKDALRRFPKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPSNPPSV--G 114 Query: 140 QTCSVAGWGQ-TAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTS 198 C + GWG T+P + + + C++ + + LC G E K + Sbjct: 115 SVCRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAYKGL--AATTLCAGILEGGKDT 172 Query: 199 FKGDSGGPLVCNKVAQGIVS-YGRNNG--MPPRACTKVSSFVHWIKKTM 244 KGDSGGPL+CN QGI+S G P TKV + WI+ + Sbjct: 173 CKGDSGGPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSII 221 >6QHB-A nrPDB Length = 223 Score = 263 bits (673), Expect = 4e-71, Method: Composition-based stats. Identities = 81/227 (35%), Positives = 116/227 (51%), Gaps = 10/227 (4%) Query: 22 IGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIKE 81 + G S PY A L CGG LI +VLTAAHC ++ V LG HN+ + Sbjct: 2 VHGGPCDKTSHPYQAALYT---SGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLGQ 58 Query: 82 QEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQT 141 QE +Q+ V R + HP Y+ + DIMLL+L R AK + +QPL L + + + Sbjct: 59 QESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSAQT--TS 116 Query: 142 CSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFKG 201 C + GWG+TA G T+Q + + +CE + LC GD + K S +G Sbjct: 117 CHILGWGKTAD-GDFPDTIQCAYIHLVSREECEHAYPGQITQNM-LCAGDEKYGKDSCQG 174 Query: 202 DSGGPLVCNKVAQGIVSYG---RNNGMPPRACTKVSSFVHWIKKTMK 245 DSGGPLVC +G+VS+G + P T V + +WI+KT++ Sbjct: 175 DSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQ 221 >3S9B-A nrPDB Length = 234 Score = 262 bits (670), Expect = 1e-70, Method: Composition-based stats. Identities = 64/228 (28%), Positives = 103/228 (45%), Gaps = 8/228 (3%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 ++GG E + P++ L ++ C G LI ++VLTAAHC +I + LG H+ Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIH-CAGALINREWVLTAAHCDRRNIRIKLGMHSKN 59 Query: 81 EQEPTQQ-FIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 + +Q +P + P DIML++L R + + P+ LPS V G Sbjct: 60 IRNEDEQIRVPRGKYFCLNTKFPNGLDKDIMLIRLRRPVTYSTHIAPVSLPSRSRGV--G 117 Query: 140 QTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 199 C + GWG+ + + + + + + CE + LC G + + + Sbjct: 118 SRCRIMGWGKISTT-TYPDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAGILKGGRDTC 176 Query: 200 KGDSGGPLVCNKVAQGIVSYG-RNNGM--PPRACTKVSSFVHWIKKTM 244 GDSGGPL+CN GIV+ G G P TKV + +WI+ + Sbjct: 177 HGDSGGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSII 224 >2CGA-A nrPDB Length = 245 Score = 262 bits (670), Expect = 1e-70, Method: Composition-based stats. Identities = 72/252 (28%), Positives = 113/252 (44%), Gaps = 23/252 (9%) Query: 1 MQPILLLLAFLLLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVL 60 +QP+L L+ I+ G EA P S P+ L D+ CGG LI +++V+ Sbjct: 6 IQPVLSGLS----------RIVNGEEAVPGSWPWQVSLQ--DKTGFHFCGGSLINENWVV 53 Query: 61 TAAHCWGSSINVTL-GAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAK 119 TAAHC ++ +V + G + Q + + + + YN +NDI LL+L A Sbjct: 54 TAAHCGVTTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAAS 113 Query: 120 RTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLR 178 ++ V + LPS G TC GWG T LQ+ + + + C+ Sbjct: 114 FSQTVSAVCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKK-YW 172 Query: 179 HYYDSTIELCVGDPEIKKTSFKGDSGGPLVCN----KVAQGIVSYGRNNG--MPPRACTK 232 +C G +S GDSGGPLVC GIVS+G + P + Sbjct: 173 GTKIKDAMICAGAS--GVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYAR 230 Query: 233 VSSFVHWIKKTM 244 V++ V+W+++T+ Sbjct: 231 VTALVNWVQQTL 242 >4E7N-A nrPDB Length = 238 Score = 261 bits (667), Expect = 3e-70, Method: Composition-based stats. Identities = 70/231 (30%), Positives = 108/231 (46%), Gaps = 10/231 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 IIGG E + ++ L + CGG LI ++VLTAAHC + + LG H+ K Sbjct: 1 IIGGDECNINEHRFLVALYT-SRSRTLFCGGTLINQEWVLTAAHCDRKNFRIKLGMHSKK 59 Query: 81 EQEPTQQ-FIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 +Q +P ++ + N + DIML++L+ K ++ + P + G Sbjct: 60 VPNEDEQTRVPKEKFFCLSSKNYTLWDKDIMLIRLDSPVKNSKHIAPFS--LPSSPPSVG 117 Query: 140 QTCSVAGWGQTAPL-GKHSHTLQEVKMTVQEDRKCESDLRHY--YDSTIELCVGDPEIKK 196 C + GWG+ +P G + V + + E C + + ++ LC G E K Sbjct: 118 SVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCAGILEGGK 177 Query: 197 TSFKGDSGGPLVCNKVAQGIVSYG-RNNGMP--PRACTKVSSFVHWIKKTM 244 + KGDSGGPL+CN QGI S+G P P A TKV + WI+ + Sbjct: 178 DTCKGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENII 228 >1PYT-D nrPDB Length = 251 Score = 260 bits (665), Expect = 4e-70, Method: Composition-based stats. Identities = 71/247 (28%), Positives = 109/247 (44%), Gaps = 14/247 (5%) Query: 12 LLPRADAGEIIGGHEAKPHSRPYMAYLMI-WDQKSLKRCGGFLIRDDFVLTAAHCWGSS- 69 + + ++GG +A PHS P+ L D CGG LI + VLTAAHC ++ Sbjct: 5 IFQPNLSARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCISNTL 64 Query: 70 -INVTLGAHNIK-EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPL 127 V LG +N++ E E ++ V H +N NDI L++L + +Q Sbjct: 65 TYRVALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELGDTIQVA 124 Query: 128 RLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCES-DLRHYYDSTIE 186 LPS + + C V GWG+ G + LQ+ V + C D Sbjct: 125 CLPSEGSLLPQDYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQRDWWGTTVKETM 184 Query: 187 LCVGDPEIKKTSFKGDSGGPLVC----NKVAQGIVSYGRN----NGMPPRACTKVSSFVH 238 +C G + ++ GDSGGPL C +GIVS+G P T+VS+++ Sbjct: 185 VCAGG-DGVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPTVFTRVSAYID 243 Query: 239 WIKKTMK 245 WI + ++ Sbjct: 244 WINQKLQ 250 >5FCR-A nrPDB Length = 234 Score = 259 bits (663), Expect = 7e-70, Method: Composition-based stats. Identities = 75/232 (32%), Positives = 120/232 (51%), Gaps = 14/232 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG-----SSINVTLG 75 I+GG EA H+RPYMA + + CGG L+ + +VL+AAHC S+ V LG Sbjct: 1 ILGGQEAAAHARPYMASVQV---NGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLG 57 Query: 76 AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ 135 AH++ EP +++ V+ +PHP P + +D++L +L + A V+PL L + Sbjct: 58 AHSLSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDKE 117 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCE-SDLRHYYDSTIELCVGDPEI 194 V+PG C VAGWG G+ L ++++++ C + +C Sbjct: 118 VEPGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCA--ESN 175 Query: 195 KKTSFKGDSGGPLVCNKVAQGIVSYG---RNNGMPPRACTKVSSFVHWIKKT 243 ++ + +GDSG PLVC +G+V++G NG P T+VSS+ WI+ Sbjct: 176 RRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENI 227 >3P8G-A nrPDB Length = 241 Score = 258 bits (659), Expect = 2e-69, Method: Composition-based stats. Identities = 71/241 (29%), Positives = 107/241 (44%), Gaps = 21/241 (8%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW----------GSSI 70 ++GG +A P+ L Q CG LI +++++AAHC+ + Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQ--GHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQW 58 Query: 71 NVTLGAHNIKEQE-PTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRL 129 LG H+ ++ P Q +KR I HP +N F DI LL+LE+ A+ + V+P+ L Sbjct: 59 TAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICL 118 Query: 130 PSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCV 189 P G+ V GWG T G + LQ+ ++ V + CE+ L + CV Sbjct: 119 PDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVIQQTTCENLLPQQITPRMM-CV 177 Query: 190 GDPEIKKTSFKGDSGGPLVC-----NKVAQGIVSYGRNNGM--PPRACTKVSSFVHWIKK 242 G S +GDSGGPL G+VS+G P T++ F WIK+ Sbjct: 178 GFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLPLFRDWIKE 237 Query: 243 T 243 Sbjct: 238 N 238 >2OCV-B nrPDB Length = 259 Score = 258 bits (659), Expect = 2e-69, Method: Composition-based stats. Identities = 67/259 (25%), Positives = 103/259 (39%), Gaps = 34/259 (13%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-----WGSSIN---- 71 I+ G +A+ P+ L + L CG LI D +VLTAAHC W + Sbjct: 1 IVEGWDAEKGIAPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCILYPPWDKNFTENDL 59 Query: 72 -VTLGAHNIKEQEPTQQFIPV-KRPIPHPAYNP-KNFSNDIMLLQLERKAKRTRAVQPLR 128 V +G H+ E + I + ++ HP YN +N DI LL+L++ + + P+ Sbjct: 60 LVRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVC 119 Query: 129 LPSNKAQ---VKPGQTCSVAGWGQTAPLGK------HSHTLQEVKMTVQEDRKCESDLRH 179 LP + ++ G V GWG LQ V + + E C++ R Sbjct: 120 LPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRI 179 Query: 180 YYDSTIELCVGD---PEIKKTSFKGDSGGPLVCN------KVAQGIVSYGRNNGMPP--R 228 + C G + + +GDSGGP V GIVS+G Sbjct: 180 RITDNM-FCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRKGKYG 238 Query: 229 ACTKVSSFVHWIKKTMKRY 247 T V WI+K + ++ Sbjct: 239 FYTHVFRLKAWIQKVIDQF 257 >1ORF-A nrPDB Length = 234 Score = 257 bits (658), Expect = 2e-69, Method: Composition-based stats. Identities = 94/234 (40%), Positives = 127/234 (54%), Gaps = 12/234 (5%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-WGSSINVTLGAHNI 79 IIGG+E PHSRPYM L + + C G LI D+VLTAAHC V LGAH+I Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRK---TICAGALIAKDWVLTAAHCNLNKRSQVILGAHSI 57 Query: 80 KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 +EPT+Q + VK+ P+P Y+P D+ LLQL KAK + V L LP VKPG Sbjct: 58 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDVKPG 117 Query: 140 QTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTI---ELCVGDPEIKK 196 C VAGWG+T S TL+EV++T+ + + C + ++ I +C G + Sbjct: 118 TMCQVAGWGRTHNSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 177 Query: 197 TSFKGDSGGPLVCNKVAQGIVSYGRN--NGMP--PRACTKVS-SFVHWIKKTMK 245 S GDSG PL+C V +G+ S+G G P P +S ++WI T+K Sbjct: 178 DSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 231 >2V35-A nrPDB Length = 240 Score = 257 bits (658), Expect = 3e-69, Method: Composition-based stats. Identities = 69/238 (28%), Positives = 110/238 (46%), Gaps = 15/238 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQK-SLKRCGGFLIRDDFVLTAAHCWGS--SINVTLGAH 77 ++GG EA+ +S P L CGG LIR ++V+TAAHC + V +G H Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEH 60 Query: 78 NIKEQEPTQQFIPVKRPIPHPAYNPKNF--SNDIMLLQLERKAKRTRAVQPLRLPSNKAQ 135 N+ + + T+Q++ V++ + HP +N + DI LL+L + VQ LP Sbjct: 61 NLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRAGTI 120 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESD-LRHYYDSTIELCVGDPEI 194 + C + GWG T G+ + TLQ+ + + C S +C G + Sbjct: 121 LANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCAGG-DG 179 Query: 195 KKTSFKGDSGGPLVC----NKVAQGIVSY----GRNNGMPPRACTKVSSFVHWIKKTM 244 ++ +GDSGGPL C G+ S+ G N P T+VS+++ WI + Sbjct: 180 VRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNVI 237 >1VR1-H nrPDB Length = 261 Score = 257 bits (657), Expect = 3e-69, Method: Composition-based stats. Identities = 65/262 (24%), Positives = 102/262 (38%), Gaps = 36/262 (13%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKS---LKRCGGFLIRDDFVLTAAHC-----WGSSIN- 71 I+ G +A+ P+ L ++S CG LI D +VLTAAHC W + Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 72 ----VTLGAHNIKEQEPTQQFIPV-KRPIPHPAYNP-KNFSNDIMLLQLERKAKRTRAVQ 125 V +G H+ E + I + ++ HP YN +N DI L++L++ + + Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 120 Query: 126 PLRLPSNKAQ---VKPGQTCSVAGWGQTAPLGK------HSHTLQEVKMTVQEDRKCESD 176 P+ LP + ++ G V GWG LQ V + + E C+ Sbjct: 121 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDS 180 Query: 177 LRHYYDSTIELCVGD---PEIKKTSFKGDSGGPLVCN------KVAQGIVSYGRNNGM-- 225 R + C + + +GDSGGP V GIVS+G Sbjct: 181 TRIRITDNM-FCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDG 239 Query: 226 PPRACTKVSSFVHWIKKTMKRY 247 T V WI+K + ++ Sbjct: 240 KYGFYTHVFRLKKWIQKVIDQF 261 >1ETT-H nrPDB Length = 259 Score = 254 bits (650), Expect = 2e-68, Method: Composition-based stats. Identities = 71/258 (27%), Positives = 103/258 (39%), Gaps = 34/258 (13%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-----WGSSIN---- 71 I+ G +A+ P+ L + L CG LI D +VLTAAHC W + Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTVDDL 59 Query: 72 -VTLGAHNIKEQEPTQQFIPV-KRPIPHPAYNP-KNFSNDIMLLQLERKAKRTRAVQPLR 128 V +G H+ E + I + + HP YN +N DI LL+L+R + + + P+ Sbjct: 60 LVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVC 119 Query: 129 LPSNKAQVK---PGQTCSVAGWGQ------TAPLGKHSHTLQEVKMTVQEDRKCESDLRH 179 LP + K G V GWG T+ LQ V + + E C++ R Sbjct: 120 LPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKASTRI 179 Query: 180 YYDSTIELCVGD---PEIKKTSFKGDSGGPLVCN------KVAQGIVSYGRNNGM--PPR 228 + C G + + +GDSGGP V GIVS+G Sbjct: 180 RITDNM-FCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEGCDRDGKYG 238 Query: 229 ACTKVSSFVHWIKKTMKR 246 T V WI+K + R Sbjct: 239 FYTHVFRLKKWIQKVIDR 256 >4Z6A-H nrPDB Length = 249 Score = 253 bits (647), Expect = 4e-68, Method: Composition-based stats. Identities = 66/239 (27%), Positives = 107/239 (44%), Gaps = 18/239 (7%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGS-----SINVTLG 75 I+GG P+ L++ + CGG LI +V++AAHC+ ++ LG Sbjct: 1 IVGGKVCPKGECPWQVLLLV---NGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLG 57 Query: 76 AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPS---N 132 H++ E + +Q V + I Y P ++DI LL+L + T V PL LP + Sbjct: 58 EHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFS 117 Query: 133 KAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDP 192 + + + V+GWGQ G + L + + + CE+ + C G Sbjct: 118 ERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEASYPGKITEYM-FCAGYS 176 Query: 193 EIKKTSFKGDSGGPLVCN----KVAQGIVSYGRNNGMPP--RACTKVSSFVHWIKKTMK 245 + K S KGDSGGP + GIVS+G+ T+VS ++ W++K M+ Sbjct: 177 DGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMR 235 >1OP0-A nrPDB Length = 234 Score = 253 bits (646), Expect = 7e-68, Method: Composition-based stats. Identities = 63/229 (27%), Positives = 97/229 (42%), Gaps = 10/229 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 +IGG+E + ++ + CGG LI ++V+TAAHC + + LG H+ K Sbjct: 1 VIGGNECDINEHRFLVAFF---NTTGFFCGGTLINPEWVVTAAHCDSTDFQMQLGVHSKK 57 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKN-FSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 +Q K P N DIML++L++ ++ + PL + G Sbjct: 58 VLNEDEQTRNPKEKFICPNKNNNEVLDKDIMLIKLDKPISNSKHIAPLS--LPSSPPSVG 115 Query: 140 QTCSVAGWGQTAP-LGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTS 198 C + GWG P + + + C++ LC G + K + Sbjct: 116 SVCRIMGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGIVQGGKDT 175 Query: 199 FKGDSGGPLVCNKVAQGIVSYG---RNNGMPPRACTKVSSFVHWIKKTM 244 GDSGGPL+CN QGIVSYG G P T V + WI++ + Sbjct: 176 CGGDSGGPLICNGQFQGIVSYGAHPCGQGPKPGIYTNVFDYTDWIQRNI 224 >1ELT-A nrPDB Length = 236 Score = 253 bits (646), Expect = 7e-68, Method: Composition-based stats. Identities = 73/238 (30%), Positives = 107/238 (44%), Gaps = 16/238 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSL-KRCGGFLIRDDFVLTAAHCWGS--SINVTLGAH 77 ++GG A+P+S P+ L S CGG LIR +V+TAAHC S + V LG H Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSARTWRVVLGEH 60 Query: 78 NIKEQEPTQQFIPVKRPIPHPAYNPKNF--SNDIMLLQLERKAKRTRAVQPLRLPSNKAQ 135 N+ E +Q + V H +N + DI LL+L +A AVQ LP + Sbjct: 61 NLNTNEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPSNQI 120 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESD-LRHYYDSTIELCVGDPEI 194 + C + GWG+T+ G S +L++ + + C S T +C G Sbjct: 121 LPNNNPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSSSGWWGSTVKTTMVCAGG--G 178 Query: 195 KKTSFKGDSGGPLVCN----KVAQGIVSY----GRNNGMPPRACTKVSSFVHWIKKTM 244 + GDSGGPL C G+ S+ G N P T+VS+++ W+ M Sbjct: 179 ANSGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAYISWMNGIM 236 >1GVZ-A nrPDB Length = 237 Score = 253 bits (646), Expect = 7e-68, Method: Composition-based stats. Identities = 78/241 (32%), Positives = 118/241 (48%), Gaps = 21/241 (8%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 IIGG E + HS+P+ + + +CGG L+ +VLTAAHC + LG HN+ Sbjct: 1 IIGGWECEKHSKPWQVAVY---HQGHFQCGGVLVHPQWVLTAAHCMSDDYQIWLGRHNLS 57 Query: 81 EQEPTQQFIPVKRPIPHPAYN-----------PKNFSNDIMLLQLERKAKRTRAVQPLRL 129 + E T QF V P ++ + S+D+MLL+L + A+ T AV+ L L Sbjct: 58 KDEDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVKILDL 117 Query: 130 PSNKAQVKPGQTCSVAGWGQTAP-LGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELC 188 P+ + ++ G TC +GWG + + S TLQ V++ +Q + KC LC Sbjct: 118 PTQEPKL--GSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARAYPEKMT-EFVLC 174 Query: 189 VGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYG-RNNGMPPR--ACTKVSSFVHWIKKTMK 245 + + GDSGG L+C+ V QGI S+G TKV WIK+T++ Sbjct: 175 ATHRDDSGSICLGDSGGALICDGVFQGITSWGYSECADFNDNFVFTKVMPHKKWIKETIE 234 Query: 246 R 246 + Sbjct: 235 K 235 >2BDH-A nrPDB Length = 223 Score = 252 bits (645), Expect = 7e-68, Method: Composition-based stats. Identities = 76/229 (33%), Positives = 123/229 (53%), Gaps = 11/229 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 II G + PHS+P+ A L++ ++ C G L+ +VL+AAHC+ +S + LG H+++ Sbjct: 1 IINGEDCSPHSQPWQAALVMENE---LFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLE 57 Query: 81 -EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 +QEP Q + + HP YN +ND+ML++L+ + ++ + + S G Sbjct: 58 ADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQC--PTAG 115 Query: 140 QTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 199 +C V+GWG A G+ LQ V ++V + C Y ++ C G + +K S Sbjct: 116 NSCLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSM-FCAGGGQDQKDSC 173 Query: 200 KGDSGGPLVCNKVAQGIVSYGR-NNGM--PPRACTKVSSFVHWIKKTMK 245 GDSGGPL+CN QG+VS+G+ G P T + F WI+KT++ Sbjct: 174 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 222 >1MZD-A nrPDB Length = 240 Score = 252 bits (645), Expect = 8e-68, Method: Composition-based stats. Identities = 92/237 (38%), Positives = 126/237 (53%), Gaps = 16/237 (6%) Query: 20 EIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-----WGSSINVTL 74 EIIGG E PHSRP+MA + CGG LI +VLTAAHC G S V L Sbjct: 2 EIIGGKEVSPHSRPFMASIQYG---GHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVL 58 Query: 75 GAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKA 134 GAH++ + E ++Q + +K+ IP SNDIML++L+ AK + V+ L + +K Sbjct: 59 GAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHI-RSKT 117 Query: 135 QVKPGQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTI---ELCVG 190 ++ G C V GWG T P + S TL+EV +TV + C S + D I +C G Sbjct: 118 SLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAG 177 Query: 191 DPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNNG--MPPRACTKVS-SFVHWIKKTM 244 D + +K S KGD+GGPL+C V IVS G G P T ++ + WIK + Sbjct: 178 DAKGQKDSCKGDAGGPLICKGVFHAIVSGGHECGVATKPGIYTLLTKKYQTWIKSNL 234 >1YC0-A nrPDB Length = 283 Score = 252 bits (644), Expect = 1e-67, Method: Composition-based stats. Identities = 78/244 (31%), Positives = 124/244 (50%), Gaps = 22/244 (9%) Query: 20 EIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW-----GSSINVTL 74 IIGG + P S P++A + I D C G L+ +V++AAHC+ S++V L Sbjct: 35 RIIGGSSSLPGSHPWLAAIYIGDS----FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVL 90 Query: 75 GAHNIKEQEPTQQFIPVKRPIPHPAYNPKN-FSNDIMLLQLERK----AKRTRAVQPLRL 129 G H Q +++ IP+ Y+ N +D++L++L++K A R++ VQP+ L Sbjct: 91 GQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICL 150 Query: 130 PSNKAQVKPGQTCSVAGWGQT-APLGKHSHTLQEVKMTVQEDRKCESDLRHYYD-STIEL 187 P + G C +AGWG + +S +L+E + + D KC S + D S L Sbjct: 151 PEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNML 210 Query: 188 CVGDPEIKKTSFKGDSGGPLVCNK----VAQGIVSYGRNNGM--PPRACTKVSSFVHWIK 241 C G + K + +GDSGGPL C K GI+S+G G P T+V+++V WI Sbjct: 211 CAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWIN 270 Query: 242 KTMK 245 ++ Sbjct: 271 DRIR 274 >3S69-A nrPDB Length = 234 Score = 251 bits (642), Expect = 2e-67, Method: Composition-based stats. Identities = 66/229 (28%), Positives = 105/229 (45%), Gaps = 10/229 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 +IGG E + L+ + + C G LI +++VLTAAHC ++ + LG H+ K Sbjct: 1 VIGGDECNINEHR---SLVAFFNSTGFFCSGTLINEEWVLTAAHCDNTNFQMKLGVHSKK 57 Query: 81 EQEPTQQFI-PVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 +Q P ++ I N + DIML++L+ + + + + L + G Sbjct: 58 VLNEDEQTRNPKEKFICPNKKNDEVLDKDIMLIKLDSRVSNSEHI--VPLSLPSSPPSVG 115 Query: 140 QTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTS 198 C + GWG P+ + + + +D C++ LC G E K + Sbjct: 116 SVCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGILEGGKDT 175 Query: 199 FKGDSGGPLVCNKVAQGIVSYG---RNNGMPPRACTKVSSFVHWIKKTM 244 GDSGGPL+CN QGIVS+G G+ P TKV + HWI+ + Sbjct: 176 CGGDSGGPLICNGQFQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSII 224 >3F6U-H nrPDB Length = 240 Score = 251 bits (641), Expect = 2e-67, Method: Composition-based stats. Identities = 67/241 (27%), Positives = 107/241 (44%), Gaps = 20/241 (8%) Query: 22 IGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSIN--VTLGAHNI 79 I G + P+ L+ D K CG LI +VLTAAHC S V LG +++ Sbjct: 2 IDGKMTRRGDSPWQVVLL--DSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDL 59 Query: 80 KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNK----AQ 135 + E + + +K HP Y+ NDI LL L + A ++ + P+ LP + Sbjct: 60 RRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAEREL 119 Query: 136 VKPGQTCSVAGWGQTAPLG-----KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVG 190 + GQ V GWG + + L +K+ V +C + + + LC G Sbjct: 120 NQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENM-LCAG 178 Query: 191 DPEIKKTSFKGDSGGPLVCN----KVAQGIVSYGRNNGMP--PRACTKVSSFVHWIKKTM 244 ++ + +GDSGGP+V + G+VS+G G+ TKVS ++ WI + Sbjct: 179 ILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWIHGHI 238 Query: 245 K 245 + Sbjct: 239 R 239 >1BQY-A nrPDB Length = 234 Score = 250 bits (639), Expect = 4e-67, Method: Composition-based stats. Identities = 62/229 (27%), Positives = 100/229 (43%), Gaps = 10/229 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 + GG E + L++ + CGG LI D+V+TAAHC ++ + G H+ K Sbjct: 1 VFGGDECNINEHR---SLVVLFNSNGFLCGGTLINQDWVVTAAHCDSNNFQLLFGVHSKK 57 Query: 81 EQEPTQQFI-PVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 +Q P ++ DIML++L+ + + PL + G Sbjct: 58 ILNEDEQTRDPKEKFFCPNRKKDDEVDKDIMLIKLDSSVSNSEHIAPLS--LPSSPPSVG 115 Query: 140 QTCSVAGWGQTAPLGK-HSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTS 198 C + GWG+T P + + + + + C + + LC G + + + Sbjct: 116 SVCRIMGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGILQGGRDT 175 Query: 199 FKGDSGGPLVCNKVAQGIVSY-GRNNGMP--PRACTKVSSFVHWIKKTM 244 DSGGPL+CN + QGIVS+ G G P P TKV ++ WIK + Sbjct: 176 CHFDSGGPLICNGIFQGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSII 224 >1BDA-A nrPDB Length = 265 Score = 250 bits (639), Expect = 5e-67, Method: Composition-based stats. Identities = 71/252 (28%), Positives = 112/252 (44%), Gaps = 26/252 (10%) Query: 20 EIIGGHEAKPHSRPYMAYLMIWDQKS---LKRCGGFLIRDDFVLTAAHCWGSSI-----N 71 I GG A S P+ A + ++S CGG LI ++L+AAHC+ Sbjct: 13 RIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLT 72 Query: 72 VTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERK----AKRTRAVQPL 127 V LG +Q V++ I H ++ + NDI LLQL+ A+ + V+ + Sbjct: 73 VILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTV 132 Query: 128 RLPSNKAQVKPGQTCSVAGWGQTAPLGK-HSHTLQEVKMTVQEDRKC-ESDLRHYYDSTI 185 LP Q+ C ++G+G+ L +S L+E + + +C L + + Sbjct: 133 CLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDN 192 Query: 186 ELCVGDPEIKK------TSFKGDSGGPLVC----NKVAQGIVSYGRNNGMP--PRACTKV 233 LC GD + +GDSGGPLVC GI+S+G G P TKV Sbjct: 193 MLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKV 252 Query: 234 SSFVHWIKKTMK 245 ++++ WI+ M+ Sbjct: 253 TNYLDWIRDNMR 264 >1FIZ-A nrPDB Length = 263 Score = 248 bits (635), Expect = 1e-66, Method: Composition-based stats. Identities = 75/248 (30%), Positives = 110/248 (44%), Gaps = 24/248 (9%) Query: 21 IIGGHEAKPHSRPYMAYLMIW---DQKSLKRCGGFLIRDDFVLTAAHCWGSSINVT---- 73 ++GG A+P + P+M L I+ + + CGG L+ +VLTAAHC+ + VT Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 74 -LGAHNI-----KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPL 127 GA+ + K +P Q V+ I H Y NDI L+++ + P Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGPG 120 Query: 128 RLPSNKAQVK-PGQTCSVAGWGQTAPLGK-HSHTLQEVKMTVQEDRKCESDLRHY-YDST 184 LP KA QTC V GWG G S TLQE ++ + + C S + + Sbjct: 121 CLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRIRS 180 Query: 185 IELCVGDPEIKKTSFKGDSGGPLVCNK------VAQGIVSYGRNNGMP--PRACTKVSSF 236 +C G P K + +GDSGGPL+C V GI S+G P T + Sbjct: 181 TNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGVGCARAKRPGVYTSTWPY 240 Query: 237 VHWIKKTM 244 ++WI + Sbjct: 241 LNWIASKI 248 >2R0L-A nrPDB Length = 248 Score = 248 bits (633), Expect = 2e-66, Method: Composition-based stats. Identities = 78/243 (32%), Positives = 124/243 (51%), Gaps = 22/243 (9%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW-----GSSINVTLG 75 IIGG + P S P++A + I D C G L+ +V++AAHC+ S++V LG Sbjct: 1 IIGGSSSLPGSHPWLAAIYIGDS----FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLG 56 Query: 76 AHNIKEQEPTQQFIPVKRPIPHPAYNPKN-FSNDIMLLQLERK----AKRTRAVQPLRLP 130 H Q +++ IP+ Y+ N +D++L++L++K A R++ VQP+ LP Sbjct: 57 QHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLP 116 Query: 131 SNKAQVKPGQTCSVAGWGQT-APLGKHSHTLQEVKMTVQEDRKCESDLRHYYD-STIELC 188 + G C +AGWG + +S +L+E + + D KC S + D S LC Sbjct: 117 EPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLC 176 Query: 189 VGDPEIKKTSFKGDSGGPLVCNK----VAQGIVSYGRNNGM--PPRACTKVSSFVHWIKK 242 G + K + +GDSGGPL C K GI+S+G G P T+V+++V WI Sbjct: 177 AGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWIND 236 Query: 243 TMK 245 ++ Sbjct: 237 RIR 239 >1SC8-U nrPDB Length = 262 Score = 246 bits (629), Expect = 5e-66, Method: Composition-based stats. Identities = 71/248 (28%), Positives = 111/248 (44%), Gaps = 21/248 (8%) Query: 20 EIIGGHEAKPHSRPYMAYLMIWDQKSL--KRCGGFLIRDDFVLTAAHCW-----GSSINV 72 +IIGG ++P+ A + + CGG LI +V++A HC+ V Sbjct: 15 KIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIV 74 Query: 73 TLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKN--FSNDIMLLQLERK----AKRTRAVQP 126 LG + + V+ I H Y+ NDI LL++ K A+ +R +Q Sbjct: 75 YLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQT 134 Query: 127 LRLPSNKAQVKPGQTCSVAGWGQTAPLGK-HSHTLQEVKMTVQEDRKCES-DLRHYYDST 184 + LPS + G +C + G+G+ + L+ + + R+C+ +T Sbjct: 135 ISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTT 194 Query: 185 IELCVGDPEIKKTSFKGDSGGPLVCN----KVAQGIVSYGRNNGM--PPRACTKVSSFVH 238 LC DP+ K S +GDSGGPLVC+ GIVS+GR + P T+VS F+ Sbjct: 195 KMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLP 254 Query: 239 WIKKTMKR 246 WI+ K Sbjct: 255 WIRSHTKE 262 >1FIW-A nrPDB Length = 290 Score = 246 bits (629), Expect = 7e-66, Method: Composition-based stats. Identities = 75/248 (30%), Positives = 112/248 (45%), Gaps = 24/248 (9%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKS---LKRCGGFLIRDDFVLTAAHCWGSSINVT---- 73 IIGG +A + P+M L I+ + CGG L+ ++LTAAHC+ VT Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 74 -LGAHNI-----KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPL 127 GA + K +P Q V++ I H Y+ + +NDI L+++ + P Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGPG 120 Query: 128 RLPSNKAQVK-PGQTCSVAGWGQTAPL-GKHSHTLQEVKMTVQEDRKCESDLRHY-YDST 184 LP +A QTC VAGWG + S LQE ++ + + C S + + Sbjct: 121 CLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGRIRS 180 Query: 185 IELCVGDPEIKKTSFKGDSGGPLVCNK------VAQGIVSYGRNNGMP--PRACTKVSSF 236 +C G PE K + +GDSGGPL+C V GI S+G P T S+ Sbjct: 181 TNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGVGCARAKRPGVYTSTWSY 240 Query: 237 VHWIKKTM 244 ++WI + Sbjct: 241 LNWIASKI 248 >1A5I-A nrPDB Length = 265 Score = 246 bits (628), Expect = 8e-66, Method: Composition-based stats. Identities = 71/248 (28%), Positives = 113/248 (45%), Gaps = 26/248 (10%) Query: 23 GGHEAKPHSRPYMAYLMIWDQKS---LKRCGGFLIRDDFVLTAAHCWGSSI-----NVTL 74 GG S P+ A + +++S CGG LI +VLTAAHC+ S V L Sbjct: 16 GGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVVL 75 Query: 75 GAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERK----AKRTRAVQPLRLP 130 G + +Q VK+ I H ++ ++NDI LLQL+ A+ + +V+ + LP Sbjct: 76 GRTYRVKPGEEEQTFKVKKYIVHKEFDDDTYNNDIALLQLKSDSPQCAQESDSVRAICLP 135 Query: 131 SNKAQVKPGQTCSVAGWGQTAPLGK-HSHTLQEVKMTVQEDRKCESDLRHYYD-STIELC 188 Q+ C ++G+G+ +S L+E + + +C + LC Sbjct: 136 EANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCAPKFLFNKTVTNNMLC 195 Query: 189 VGDPEIKK------TSFKGDSGGPLVC----NKVAQGIVSYGRNNGMP--PRACTKVSSF 236 GD + + +GDSGGPLVC + GI+S+G G P TKV+++ Sbjct: 196 AGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWGVGCGEKDVPGVYTKVTNY 255 Query: 237 VHWIKKTM 244 + WI+ M Sbjct: 256 LGWIRDNM 263 >5LHN-A nrPDB Length = 247 Score = 245 bits (627), Expect = 9e-66, Method: Composition-based stats. Identities = 74/248 (29%), Positives = 114/248 (45%), Gaps = 26/248 (10%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLK---RCGGFLIRDDFVLTAAHCW-----GSSINV 72 I+GG + ++P+ A + ++ +CGG LI +V +AAHC+ + V Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 73 TLGAHNIKEQEPTQQFIPVKRPIPHPAY--NPKNFSNDIMLLQLERK----AKRTRAVQP 126 LG P + V++ I H Y + + NDI LL++ A+ +R++Q Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQT 120 Query: 127 LRLPSNKAQVKPGQTCSVAGWGQTAPLGK-HSHTLQEVKMTVQEDRKCESDLRHYYDSTI 185 + LP G C + G+G+ + + L+ + + +C HYY S I Sbjct: 121 IALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQ--PHYYGSEI 178 Query: 186 ---ELCVGDPEIKKTSFKGDSGGPLVCN----KVAQGIVSYGRNNGM--PPRACTKVSSF 236 LC DPE K S KGDSGGPL+CN GIVS+GR P T+VS F Sbjct: 179 NYKMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWGRGCAEKNKPGVYTRVSHF 238 Query: 237 VHWIKKTM 244 + WI+ + Sbjct: 239 LDWIQSHI 246 >2OQ5-A nrPDB Length = 232 Score = 245 bits (627), Expect = 1e-65, Method: Composition-based stats. Identities = 64/236 (27%), Positives = 99/236 (41%), Gaps = 22/236 (9%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW-----GSSINVTLG 75 I+GG E + P+ A L RCG LI ++++AAHC+ + + G Sbjct: 1 IVGGTEVEEGEWPWQASLQWD---GSHRCGATLINATWLVSAAHCFTTYKNPARWTASFG 57 Query: 76 AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ 135 +P++ ++R I H Y + DI L +L T AV + LP + Sbjct: 58 VT----IKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYE 113 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCE--SDLRHYYDSTIELCVGDPE 193 +PG V G+G G + L++ ++T+ + C LC G E Sbjct: 114 FQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITP-RMLCAGSLE 172 Query: 194 IKKTSFKGDSGGPLVCN-----KVAQGIVSYGRNNGMP--PRACTKVSSFVHWIKK 242 K + +GDSGGPLV + GIVS+G P P T+V++ WI Sbjct: 173 GKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITS 228 >5TO3-B nrPDB Length = 409 Score = 244 bits (624), Expect = 2e-65, Method: Composition-based stats. Identities = 66/259 (25%), Positives = 101/259 (38%), Gaps = 34/259 (13%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-----WGSSIN---- 71 I+ G +A+ P+ L + L CG LI D +VLTAAHC W + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 59 Query: 72 -VTLGAHNIKEQEPTQQFIPV-KRPIPHPAYNP-KNFSNDIMLLQLERKAKRTRAVQPLR 128 V +G H+ E + I + ++ HP YN +N DI L++L++ + + P+ Sbjct: 60 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 119 Query: 129 LPSNKAQ---VKPGQTCSVAGWGQTAPLGK------HSHTLQEVKMTVQEDRKCESDLRH 179 LP + ++ G V GWG LQ V + + E C+ R Sbjct: 120 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRI 179 Query: 180 YYDSTIELCVGD---PEIKKTSFKGDSGGPLVCN------KVAQGIVSYGRNNGM--PPR 228 + C G + + +GDSGGP V GIVS G Sbjct: 180 RITDNM-FCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAGAGCDRDGKYG 238 Query: 229 ACTKVSSFVHWIKKTMKRY 247 T V WI+K + ++ Sbjct: 239 FYTHVFRLKKWIQKVIDQF 257 >4XDE-A nrPDB Length = 257 Score = 243 bits (620), Expect = 6e-65, Method: Composition-based stats. Identities = 74/246 (30%), Positives = 111/246 (45%), Gaps = 29/246 (11%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSS-----INVTLG 75 ++GG A + PY+A L C G LI +VLTAAHC + V LG Sbjct: 3 VVGGLVALRGAHPYIAALYW----GHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLG 58 Query: 76 AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAK-----RTRAVQPLRLP 130 Q + V+ H A++P ++ +D+ LL+L+ A + VQP+ LP Sbjct: 59 QERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSLP 118 Query: 131 SNKAQVKPGQTCSVAGWGQTAPL-GKHSHTLQEVKMTVQEDRKCESDLRHYYDSTI---E 186 S A+ C VAGWG +++ LQE ++ +C + + S+I Sbjct: 119 SGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSA--PDVHGSSILPGM 176 Query: 187 LCVGDPEIKKTSFKGDSGGPLVCNK-------VAQGIVSYGRNNG--MPPRACTKVSSFV 237 LC G E + +GDSGGPLVC QGI+S+G G P T V+ ++ Sbjct: 177 LCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYYL 236 Query: 238 HWIKKT 243 WI++ Sbjct: 237 AWIREH 242 >4Q7Y-A nrPDB Length = 250 Score = 243 bits (620), Expect = 7e-65, Method: Composition-based stats. Identities = 93/235 (39%), Positives = 123/235 (52%), Gaps = 13/235 (5%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG----SSINVTLGA 76 IIGGHE PHSRPYMA + CGGFL+R +V++AAHC+ + V LGA Sbjct: 1 IIGGHEVTPHSRPYMASVRFG---GQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGA 57 Query: 77 HNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQV 136 H + EPTQQ + HP Y+P +NDI LL+L A AV LRLP +A+ Sbjct: 58 HVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRARP 117 Query: 137 K-PGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEI- 194 G C VAGWG + + L E K+ V + C S + + T+ LC + Sbjct: 118 PTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTM-LCTRSGDSH 176 Query: 195 KKTSFKGDSGGPLVCNKVAQGIVSY-GRNNGMP--PRACTKVSSFVHWIKKTMKR 246 ++ DSGGPLVC A G+VS+ G G P P T+VS+FV WI ++R Sbjct: 177 RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 231 >1FON-A nrPDB Length = 240 Score = 241 bits (616), Expect = 2e-64, Method: Composition-based stats. Identities = 70/239 (29%), Positives = 103/239 (43%), Gaps = 19/239 (7%) Query: 23 GGHEAKPHSRPYMAYLMI-WDQKSLKRCGGFLIRDDFVLTAAHCWGSS--INVTLGAHNI 79 G +A P+S + L D CGG LI D+V+TA HC +S V LG ++ Sbjct: 1 NGEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSRTYQVVLGEYDR 60 Query: 80 KEQEPTQQFIPVKR--PIPHPAYNPKNF--SNDIMLLQLERKAKRTRAVQPLRLPSNKAQ 135 E ++Q IP+ HP +N NDI L++L R A+ VQ LP Sbjct: 61 SVLEGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPAGDI 120 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCES-DLRHYYDSTIELCVGDPEI 194 + C ++GWG+ G LQ+ + + C D +C G Sbjct: 121 LPNEAPCYISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCAGGDT- 179 Query: 195 KKTSFKGDSGGPLVC-----NKVAQGIVS----YGRNNGMPPRACTKVSSFVHWIKKTM 244 ++ GDSGGPL C + G+ S +G N P T+VS+F+ WI +T+ Sbjct: 180 -RSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWIDETI 237 >1AZZ-A nrPDB Length = 226 Score = 239 bits (610), Expect = 9e-64, Method: Composition-based stats. Identities = 81/227 (35%), Positives = 114/227 (50%), Gaps = 14/227 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSS--INVTLGAHN 78 I+GG EA P+S P+ A L I D + CGG LI +++LTAAHC + ++V LGAHN Sbjct: 1 IVGGVEAVPNSWPHQAALFIDD---MYFCGGSLISPEWILTAAHCMDGAGFVDVVLGAHN 57 Query: 79 IKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKP 138 I+E E TQ I H YN SNDI +++L T A+ + LPS V Sbjct: 58 IREDEATQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPSTDVGV-- 115 Query: 139 GQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKT 197 G + GWG + S L++V + + + C++ D I + D K Sbjct: 116 GTVVTPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVYGIVTDGNICI---DSTGGKG 172 Query: 198 SFKGDSGGPLVCNKVAQGIVSYGRNNGMP---PRACTKVSSFVHWIK 241 + GDSGGPL N + GI S+G G P A T+V+ F+ WI+ Sbjct: 173 TCNGDSGGPLNYNGLTYGITSFGAAAGCEAGYPDAFTRVTYFLDWIQ 219 >4IW4-E nrPDB Length = 279 Score = 235 bits (599), Expect = 2e-62, Method: Composition-based stats. Identities = 74/267 (27%), Positives = 114/267 (42%), Gaps = 44/267 (16%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLK----RCGGFLIRDDFVLTAAHCWGSS------- 69 IIGG A+P P+ A +++ D + G L+ ++LTAAH S Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 70 ------INVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRA 123 + V LG H+++++ R + HP +N +N+++DI L+QL+ Sbjct: 61 PVSKEHVTVYLGLHDVRDKSGAVN-SSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPH 119 Query: 124 VQPLRLPSNKAQ-VKPGQTCSVAGWGQTAPL-----------GKHSHTLQEVKMTVQEDR 171 V P+ LP + + P VAGWG + P S LQ VK+ V Sbjct: 120 VMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHA 179 Query: 172 KCESDL----RHYYDSTIELCVGDPEIKKTSFKGDSGGPLV------CNKVAQGIVSYG- 220 +C++ +Y + C G E K + GDSGG V V QG+VS+G Sbjct: 180 ECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWGG 239 Query: 221 -RNNGMP--PRACTKVSSFVHWIKKTM 244 G TKVS++V W+ + M Sbjct: 240 PEECGSKQVYGVYTKVSNYVDWVWEQM 266 >1EQ9-A nrPDB Length = 222 Score = 234 bits (598), Expect = 2e-62, Method: Composition-based stats. Identities = 72/232 (31%), Positives = 113/232 (48%), Gaps = 16/232 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG-----SSINVTLG 75 I+GG +A PY L + RCG ++ ++ VLTAAHC + + V +G Sbjct: 1 IVGGKDAPVGKYPYQVSLRL---SGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVG 57 Query: 76 AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ 135 + + E + V+ + + Y+ ND+ L+ L K VQP++L +N Sbjct: 58 TNYLSE---SGDVYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTNDED 114 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIK 195 ++ C++ GWG T G + LQE+++ V ++CE D DS +C + Sbjct: 115 LESN-PCTLTGWGSTRLGGNTPNALQEIELIVHPQKQCERDQWRVIDSH--ICT-LTKRG 170 Query: 196 KTSFKGDSGGPLVCNKVAQGIVSYGRNNGM-PPRACTKVSSFVHWIKKTMKR 246 + + GDSGGPLV N GIVS+G + P T+VSSFV WI +K+ Sbjct: 171 EGACHGDSGGPLVANGAQIGIVSFGSPCALGEPDVYTRVSSFVSWINANLKK 222 >5XRF-A nrPDB Length = 242 Score = 234 bits (597), Expect = 3e-62, Method: Composition-based stats. Identities = 59/235 (25%), Positives = 102/235 (43%), Gaps = 8/235 (3%) Query: 15 RADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTL 74 + + +IGG+E + ++A + +C G LI +++VL AAHC+ +N+ L Sbjct: 1 QKSSELVIGGNECDTNEHRFLAAFFT-SRPWTFQCAGTLIHEEWVLAAAHCYKRGLNIYL 59 Query: 75 GAHNIKEQ-EPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNK 133 G HN Q + Q+ ++ + D++LL+L + + + PL Sbjct: 60 GMHNQSIQFDDEQRRYAIEEHYYRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPLS--LPS 117 Query: 134 AQVKPGQTCSVAGWGQTAPLGK-HSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDP 192 + G C V GWG + + + +C + ++T LC G Sbjct: 118 SPPSIGSVCRVMGWGIMSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLCAGVL 177 Query: 193 EIKKTSFKGDSGGPLVCNKVAQGIVSYG-RNNGMP--PRACTKVSSFVHWIKKTM 244 E + DSGGPL+C+ QGIV +G P P T+VS++ WI+ + Sbjct: 178 EGGIDTCNQDSGGPLICDGQFQGIVFFGKYPCAQPNKPGLYTRVSNYNDWIQNII 232 >4KKD-A nrPDB Length = 433 Score = 233 bits (596), Expect = 5e-62, Method: Composition-based stats. Identities = 73/268 (27%), Positives = 113/268 (42%), Gaps = 44/268 (16%) Query: 20 EIIGGHEAKPHSRPYMAYLMIWDQKSLK----RCGGFLIRDDFVLTAAHCWGSS------ 69 IIGG A+P P+ A +++ D + G L+ ++LTAAH S Sbjct: 154 RIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTV 213 Query: 70 -------INVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTR 122 + V LG H+++++ R + HP +N +N+++DI L+QL+ Sbjct: 214 IPVSKEHVTVYLGLHDVRDKSG-AVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGP 272 Query: 123 AVQPLRLPSNKAQ-VKPGQTCSVAGWGQTAPL-----------GKHSHTLQEVKMTVQED 170 V P+ LP + + P VAGWG + P S LQ VK+ V Sbjct: 273 HVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPH 332 Query: 171 RKCESDL----RHYYDSTIELCVGDPEIKKTSFKGDSGGPLV------CNKVAQGIVSYG 220 +C++ +Y + C G E K + GDSG V V QG+VS+G Sbjct: 333 AECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGEAFVIFDDLSQRWVVQGLVSWG 392 Query: 221 --RNNGMP--PRACTKVSSFVHWIKKTM 244 G TKVS++V W+ + M Sbjct: 393 GPEECGSKQVYGVYTKVSNYVDWVWEQM 420 >4IGD-A nrPDB Length = 406 Score = 233 bits (594), Expect = 6e-62, Method: Composition-based stats. Identities = 64/259 (24%), Positives = 103/259 (39%), Gaps = 33/259 (12%) Query: 13 LPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG----- 67 R +I G A+ + P++A L + CGG L+ +++TAAHC Sbjct: 148 FSRKLMAQIFNGRPAQKGTTPWIAMLSHLN--GQPFCGGSLLGSSWIVTAAHCLHQSLDP 205 Query: 68 -------------SSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQL 114 S + LG H + +Q + VK HP Y+P F ND+ L++L Sbjct: 206 EDPTLRDSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVEL 265 Query: 115 ERKAKRTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCE 174 V P+ LP + G V+GWG+ L + TL E+++ + + C+ Sbjct: 266 LESPVLNAFVMPICLPEGPQ--QEGAMVIVSGWGK-QFLQRFPETLMEIEIPIVDHSTCQ 322 Query: 175 SDLRHYYDSTI--ELCVGDPEIKKTSFKGDSGGPLVC------NKVAQGIVSYGRNNGMP 226 +C G+ E K + GDSGGP+V G VS+G + G Sbjct: 323 KAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKK 382 Query: 227 --PRACTKVSSFVHWIKKT 243 + + WI++ Sbjct: 383 DRYGVYSYIHHNKDWIQRV 401 >1Q3X-A nrPDB Length = 328 Score = 231 bits (591), Expect = 1e-61, Method: Composition-based stats. Identities = 67/259 (25%), Positives = 107/259 (41%), Gaps = 31/259 (11%) Query: 12 LLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW----- 66 L R G I GG +AKP P+ ++ G L+ D++VLTAAH Sbjct: 78 LSARTTGGRIYGGQKAKPGDFPWQVLIL-----GGTTAAGALLYDNWVLTAAHAVYEQKH 132 Query: 67 -GSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAY-NPKNFSNDIMLLQLERKAKRTRAV 124 S++++ +G +K P + H Y + F NDI L++L K + Sbjct: 133 DASALDIRMGT--LKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNI 190 Query: 125 QPLRLPSNKAQ--VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDL----- 177 P+ LP +A+ ++ + +GWG T G + L V + + + +KC + Sbjct: 191 TPICLPRKEAESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQKCTAAYEKPPY 249 Query: 178 RHYYDSTIELCVGDPEIKKTSFKGDSGGPLVC------NKVAQGIVSYG---RNNGMPPR 228 + LC G K S +GDSGG LV GIVS+G Sbjct: 250 PRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYG 309 Query: 229 ACTKVSSFVHWIKKTMKRY 247 TKV +++ WI+ + + Sbjct: 310 VYTKVINYIPWIENIISDF 328 >4BXW-A nrPDB Length = 423 Score = 231 bits (589), Expect = 2e-61, Method: Composition-based stats. Identities = 63/247 (25%), Positives = 104/247 (42%), Gaps = 24/247 (9%) Query: 20 EIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSS--INVTLGAH 77 I+ G + K P+ A L+ D+K CGG ++ +VLTAAHC + I+V +G Sbjct: 169 RIVNGMDCKLGECPWQAALV--DEKEGVFCGGTILSPIYVLTAAHCINETETISVVVGEI 226 Query: 78 NIKEQEPTQQFIPVKRPIPHPAYNP---------KNFSNDIMLLQLERKAKRTRAVQPLR 128 + E T + V + H + P + DI ++Q++ + + V P Sbjct: 227 DKSRIE-TGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQFSENVVPAC 285 Query: 129 LPSNK---AQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTI 185 LP+ + V+G+G+ G S TL+ +K+ + C + Sbjct: 286 LPTADFANQVLMKQDFGIVSGFGRIVEKGPKSKTLKVLKVPYVDRHTCMVSSETPITPNM 345 Query: 186 ELCVGDPEIKKTSFKGDSGGPLVC----NKVAQGIVSYGRNNGM--PPRACTKVSSFVHW 239 C G + + + +GDSGGP GIVS G TK+S F+ W Sbjct: 346 -FCAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSGEGCARNGKYGNYTKLSKFIPW 404 Query: 240 IKKTMKR 246 IK+ M++ Sbjct: 405 IKRIMRQ 411 >2ZKS-A nrPDB Length = 240 Score = 230 bits (588), Expect = 3e-61, Method: Composition-based stats. Identities = 87/236 (36%), Positives = 119/236 (50%), Gaps = 16/236 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSS---INVTLGAH 77 IIGG E PHSRPYMA L + CGG L+ +VLTAAHC + + LG H Sbjct: 1 IIGGREVIPHSRPYMASLQ---RNGSHLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLGLH 57 Query: 78 NIKEQEPTQQFIPVKRPIPHPAYNP-KNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQV 136 + + +K I HP Y P ND+ LLQL+ K K +R ++PL LPS + V Sbjct: 58 TL---DSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQVV 114 Query: 137 KPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESD-LRHYYDSTIELCVGDPEIK 195 G CS+AGWG T G+ S L+E+ + V + R C + + S +C+ Sbjct: 115 AAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAADSKD 174 Query: 196 KTSFKGDSGGPLVC--NKVAQGIVSYGRNNGM---PPRACTKVSSFVHWIKKTMKR 246 + KGDSGGPLVC +V G++S+ P T V+ +V WI+K R Sbjct: 175 QAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKVTGR 230 >1ZJK-A nrPDB Length = 403 Score = 230 bits (586), Expect = 6e-61, Method: Composition-based stats. Identities = 67/259 (25%), Positives = 108/259 (41%), Gaps = 31/259 (11%) Query: 12 LLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW----- 66 L R G+I GG +AKP P+ ++ G L+ D++VLTAAH Sbjct: 153 LSARTTGGQIYGGQKAKPGDFPWQVLIL-----GGTTAAGALLYDNWVLTAAHAVYEQKH 207 Query: 67 -GSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAY-NPKNFSNDIMLLQLERKAKRTRAV 124 S++++ +G +K P + H Y + F NDI L++L K + Sbjct: 208 DASALDIRMGT--LKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNI 265 Query: 125 QPLRLPSNKAQ--VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDL----- 177 P+ LP +A+ ++ + +GWG T G + L V + + + +KC + Sbjct: 266 TPICLPRKEAESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQKCTAAYEKPPY 324 Query: 178 RHYYDSTIELCVGDPEIKKTSFKGDSGGPLVC------NKVAQGIVSYG---RNNGMPPR 228 + LC G K S +GDSGG LV GIVS+G Sbjct: 325 PRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYG 384 Query: 229 ACTKVSSFVHWIKKTMKRY 247 TKV +++ WI+ + + Sbjct: 385 VYTKVINYIPWIENIISDF 403 >1AE5-A nrPDB Length = 225 Score = 229 bits (585), Expect = 8e-61, Method: Composition-based stats. Identities = 74/231 (32%), Positives = 110/231 (47%), Gaps = 17/231 (7%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSI----NVTLGA 76 I+GG +A+P P++A + + CGG LI FV+TAA C+ S V LGA Sbjct: 1 IVGGRKARPRQFPFLASIQ---NQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA 57 Query: 77 HNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQV 136 ++++ +E + + Y+P+ ND+MLLQL+R+A T +V L LP A V Sbjct: 58 YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATV 117 Query: 137 KPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKK 196 + G C VAGWG G+ S + V +TV + +C +C G + Sbjct: 118 EAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRP---------NNVCTGVLTRRG 168 Query: 197 TSFKGDSGGPLVCNKVAQGIVSYGRN-NGMPPRACTKVSSFVHWIKKTMKR 246 GD G PLVC +A G+ S+ G P T+V+ F WI + Sbjct: 169 GICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNN 219 >5LPF-A nrPDB Length = 234 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 66/234 (28%), Positives = 108/234 (46%), Gaps = 20/234 (8%) Query: 24 GHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIKEQE 83 G S+P+ L C G L+ +VLTAAHC + +G ++ + Sbjct: 7 GSPCARGSQPWQVSLF---NGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQ 63 Query: 84 PTQQFIPVKRPIPHPAYNP--------KNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ 135 +Q R + HP Y+ + +D+MLL+L R V+ L+LP A Sbjct: 64 G-EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCA- 121 Query: 136 VKPGQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEI 194 +PG C VAGWG TA K++ L +T+ ++CE + + +C G + Sbjct: 122 -QPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNM-ICAG-LDR 178 Query: 195 KKTSFKGDSGGPLVCNKVAQGIVSYG---RNNGMPPRACTKVSSFVHWIKKTMK 245 + + DSGGPLVC++ QGI+S+G + P T++ ++ WI K ++ Sbjct: 179 GQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIR 232 >4DJZ-B nrPDB Length = 251 Score = 228 bits (581), Expect = 2e-60, Method: Composition-based stats. Identities = 63/251 (25%), Positives = 101/251 (40%), Gaps = 33/251 (13%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG------------- 67 I G A+ + P++A L + CGG L+ +++TAAHC Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLN--GQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDS 58 Query: 68 -----SSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTR 122 S + LG H + +Q + VK HP Y+P F ND+ L++L Sbjct: 59 DLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLNA 118 Query: 123 AVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYD 182 V P+ LP + G V+GWG+ L + TL E+++ + + C+ Sbjct: 119 FVMPICLPEGPQ--QEGAMVIVSGWGK-QFLQRFPETLMEIEIPIVDHSTCQKAYAPLKK 175 Query: 183 STI--ELCVGDPEIKKTSFKGDSGGPLVC------NKVAQGIVSYGRNNGMP--PRACTK 232 +C G+ E K + GDSGGP+V G VS+G + G + Sbjct: 176 KVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKKDRYGVYSY 235 Query: 233 VSSFVHWIKKT 243 + WI++ Sbjct: 236 IHHNKDWIQRV 246 >2XRC-A nrPDB Length = 565 Score = 227 bits (580), Expect = 3e-60, Method: Composition-based stats. Identities = 71/261 (27%), Positives = 111/261 (42%), Gaps = 32/261 (12%) Query: 12 LLPRADAG----------EIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLT 61 LLP+ G I+GG A+ P+ + S CGG I ++LT Sbjct: 303 LLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAI---KDASGITCGGIYIGGCWILT 359 Query: 62 AAHCWGSSINVT--LGAHNIKEQEPTQQFIP---VKRPIPHPAYNPKNFSNDIMLLQLER 116 AAHC +S + + P + I V R I H YN + NDI L+++++ Sbjct: 360 AAHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKK 419 Query: 117 KAKRTRAVQPLRLPS----NKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRK 172 + P +P+ + +P TC V+GWG+ + +LQ ++ + + Sbjct: 420 DGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERV-FSLQWGEVKLISN-- 476 Query: 173 CESDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNK-----VAQGIVSYGRNNGMP- 226 C + + C G + + KGDSGGPLVC G+VS+G N G P Sbjct: 477 CSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPE 536 Query: 227 -PRACTKVSSFVHWIKKTMKR 246 P TKV+++ WI + R Sbjct: 537 FPGVYTKVANYFDWISYHVGR 557 >2OLG-A nrPDB Length = 278 Score = 227 bits (580), Expect = 3e-60, Method: Composition-based stats. Identities = 71/263 (26%), Positives = 119/263 (45%), Gaps = 34/263 (12%) Query: 15 RADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKR--CGGFLIRDDFVLTAAHCWGSSI-- 70 + +A +I+ G + P P+ A + + + ++ CGG LI + +++TAAHC + Sbjct: 17 QVEADKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAHCVAGRVLR 76 Query: 71 ------NVTLGAHNIKEQEPTQQFIPV-----------KRPIPHPAYNPKNFS--NDIML 111 V LG N + V + I HP Y + +DI L Sbjct: 77 VVGALNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVDGSKDRYHDIAL 136 Query: 112 LQLERKAKRTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDR 171 ++L R+ + T ++P+ LP +V+ GQ +V GWG+T G++S Q++ + V Sbjct: 137 IRLNRQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRT-ETGQYSTIKQKLAVPVVHAE 195 Query: 172 KCESDLR--HYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNK-----VAQGIVSYGRNNG 224 +C + +LC G E K S GDSGGPL+ + +G+VS+G G Sbjct: 196 QCAKTFGAAGVRVRSSQLCAGG-EKAKDSCGGDSGGPLLAERANQQFFLEGLVSFGATCG 254 Query: 225 MP--PRACTKVSSFVHWIKKTMK 245 P TKV + WI+ ++ Sbjct: 255 TEGWPGIYTKVGKYRDWIEGNIR 277 >2QY0-B nrPDB Length = 242 Score = 227 bits (579), Expect = 3e-60, Method: Composition-based stats. Identities = 79/248 (31%), Positives = 113/248 (45%), Gaps = 30/248 (12%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW---------GSSIN 71 IIGG +AK + P+ + I + GG L+ D ++LTAAH +S++ Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGRG-----GGALLGDRWILTAAHTLYPKEHEAQSNASLD 55 Query: 72 VTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPK---NFSNDIMLLQLERKAKRTRAVQPLR 128 V LG N++E P++R HP Y NF DI LL+LE + P+ Sbjct: 56 VFLGHTNVEELMKLGNH-PIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPIC 114 Query: 129 LPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHY----YDST 184 LP N G V+G+G K +H L+ V++ V + CE+ LR S Sbjct: 115 LPDNDTFYDLGLMGYVSGFGVMEE--KIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQ 172 Query: 185 IELCVGDPEIKKTSFKGDSGGPLVCN------KVAQGIVSYGRNNGMPPRACTKVSSFVH 238 C G P +K+ + +GDSGG VA GIVS+G TKV ++V Sbjct: 173 NMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRGYGFYTKVLNYVD 232 Query: 239 WIKKTMKR 246 WIKK M+ Sbjct: 233 WIKKEMEE 240 >1GPZ-A nrPDB Length = 399 Score = 226 bits (578), Expect = 5e-60, Method: Composition-based stats. Identities = 80/255 (31%), Positives = 115/255 (45%), Gaps = 30/255 (11%) Query: 14 PRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW------- 66 P +IIGG +AK + P+ + I + GG L+ D ++LTAAH Sbjct: 151 PVEQRQQIIGGQKAKMGNFPWQVFTNIHGRG-----GGALLGDRWILTAAHTLYPKEHEA 205 Query: 67 --GSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPK---NFSNDIMLLQLERKAKRT 121 +S++V LG N++E P++R HP Y NF DI LL+LE Sbjct: 206 QSNASLDVFLGHTNVEELMKLGNH-PIRRVSVHPDYRQDESYNFEGDIALLELENSVTLG 264 Query: 122 RAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHY- 180 + P+ LP N G V+G+G K +H L+ V++ V + CE+ LR Sbjct: 265 PNLLPICLPDNDTFYDLGLMGYVSGFGVMEE--KIAHDLRFVRLPVANPQACENWLRGKN 322 Query: 181 ---YDSTIELCVGDPEIKKTSFKGDSGGPLVCN------KVAQGIVSYGRNNGMPPRACT 231 S C G P +K+ + +GDSGG VA GIVS+G T Sbjct: 323 RMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRGYGFYT 382 Query: 232 KVSSFVHWIKKTMKR 246 KV ++V WIKK M+ Sbjct: 383 KVLNYVDWIKKEMEE 397 >1MD7-A nrPDB Length = 328 Score = 225 bits (573), Expect = 2e-59, Method: Composition-based stats. Identities = 79/254 (31%), Positives = 114/254 (44%), Gaps = 30/254 (11%) Query: 14 PRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW------- 66 P IIGG +AK + P+ + I + GG L+ D ++LTAAH Sbjct: 83 PVEQRQRIIGGQKAKMGNFPWQVFTNIHGRG-----GGALLGDRWILTAAHTLYPKEHEA 137 Query: 67 --GSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPK---NFSNDIMLLQLERKAKRT 121 +S++V LG N++E P++R HP Y NF DI LL+LE Sbjct: 138 QSNASLDVFLGHTNVEELMKLGNH-PIRRVSVHPDYRQDESYNFEGDIALLELENSVTLG 196 Query: 122 RAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHY- 180 + P+ LP N G V+G+G K +H L+ V++ V + CE+ LR Sbjct: 197 PNLLPICLPDNDTFYDLGLMGYVSGFGVMEE--KIAHDLRFVRLPVANPQACENWLRGKN 254 Query: 181 ---YDSTIELCVGDPEIKKTSFKGDSGGPLVCN------KVAQGIVSYGRNNGMPPRACT 231 S C G P +K+ + +GD+GG VA GIVS+G T Sbjct: 255 RMDVFSQNMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVSWGIGCSRGYGFYT 314 Query: 232 KVSSFVHWIKKTMK 245 KV ++V WIKK M+ Sbjct: 315 KVLNYVDWIKKEME 328 >5KWM-A nrPDB Length = 230 Score = 225 bits (573), Expect = 2e-59, Method: Composition-based stats. Identities = 66/225 (29%), Positives = 97/225 (43%), Gaps = 16/225 (7%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSS----INVTLGA 76 I+GG +A P+ L+ D + CGG L + V+TAAHC S INV G Sbjct: 1 IVGGEDANVQDHPFTVALVTPDGQQ--FCGGTLAAPNKVVTAAHCTVGSQPADINVVSGR 58 Query: 77 HNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLP-SNKAQ 135 + E T V HP Y D+ +L LE K P+ L ++ A Sbjct: 59 TVMSSNEGT--VSKVTNVWVHPEYQDAAKGFDVSVLTLEAPVKE----APIELAKADDAG 112 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIK 195 P ++ GWG T+ G+ + LQ+ + V D C+ Y + +C G PE Sbjct: 113 YAPDTAATILGWGNTSEGGQQADHLQKATVPVNSDDTCKQAYGEYTPDAM-VCAGVPEGG 171 Query: 196 KTSFKGDSGGPLVCNKVAQGIVSYGRNNGMP--PRACTKVSSFVH 238 + +GDSGGP+V N G+ S+G P P +V ++ Sbjct: 172 VDTCQGDSGGPMVVNNKLIGVTSWGEGCARPGKPGVYARVGAYYD 216 >4FXG-H nrPDB Length = 242 Score = 225 bits (573), Expect = 2e-59, Method: Composition-based stats. Identities = 63/250 (25%), Positives = 104/250 (41%), Gaps = 31/250 (12%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW------GSSINVTL 74 I GG +AKP P+ ++ G L+ D++VLTAAH S++++ + Sbjct: 1 IYGGQKAKPGDFPWQVLIL-----GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRM 55 Query: 75 GAHNIKEQEPTQQFIPVKRPIPHPAY-NPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNK 133 G +K P + H Y + F NDI L++L K + P+ LP + Sbjct: 56 GT--LKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKE 113 Query: 134 AQ--VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDL-----RHYYDSTIE 186 A+ ++ + +GWG T G + L V + + + +KC + + Sbjct: 114 AESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANM 172 Query: 187 LCVGDPEIKKTSFKGDSGGPLVC------NKVAQGIVSYG---RNNGMPPRACTKVSSFV 237 LC G K S +GD+GG LV GIVS+G TKV +++ Sbjct: 173 LCAGLESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYI 232 Query: 238 HWIKKTMKRY 247 WI+ + + Sbjct: 233 PWIENIISDF 242 >2XXL-A nrPDB Length = 408 Score = 223 bits (569), Expect = 5e-59, Method: Composition-based stats. Identities = 77/260 (29%), Positives = 114/260 (43%), Gaps = 36/260 (13%) Query: 18 AGEIIGGHEAKPHSRPYMAYLMIWD-QKSLKRCGGFLIRDDFVLTAAHCW----GSSINV 72 + + G+E K SRP+MA L +S CGG +I + ++LTAAHC + Sbjct: 116 SQRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDLYEI 175 Query: 73 TLGAHNIKEQEPTQQF------------IPVKRPIPHPAYNPKNFSNDIMLLQLERKAKR 120 LG H I +E +Q + +++ + H Y+ ++ +DI LL+L R Sbjct: 176 RLGEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNRSVPF 235 Query: 121 TRAVQPLRLP---SNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDL 177 + ++P+ LP K + + T V GWG T G S L + + +Q C Sbjct: 236 QKHIKPICLPITDELKEKAEQISTYFVTGWGTTEN-GSSSDVLLQANVPLQPRSACSQAY 294 Query: 178 RHYYDSTIELCVGDPEIKKTSFKGDSGGPLVC----------NKVAQGIVSYG---RNNG 224 R + +LCVG +++ S KGDSGGPL V GIVS G Sbjct: 295 RRAVPLS-QLCVGGGDLQ-DSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVVTCGQI 352 Query: 225 MPPRACTKVSSFVHWIKKTM 244 P T V +V WI TM Sbjct: 353 SLPGLYTNVGEYVQWITDTM 372 >5O32-I nrPDB Length = 244 Score = 222 bits (567), Expect = 8e-59, Method: Composition-based stats. Identities = 67/242 (27%), Positives = 106/242 (43%), Gaps = 22/242 (9%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVT--LGAHN 78 I+GG A+ P+ + S CGG I ++LTAAHC +S + Sbjct: 1 IVGGKRAQLGDLPWQVAI---KDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTV 57 Query: 79 IKEQEPTQQFIP---VKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPS---- 131 + P + I V R I H YN + NDI L+++++ + P +P+ Sbjct: 58 VDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPW 117 Query: 132 NKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGD 191 + +P TC V+GWG+ + +LQ ++ + + C + + C G Sbjct: 118 SPYLFQPNDTCIVSGWGREKDNERV-FSLQWGEVKLISN--CSKFYGNRFYEKEMECAGT 174 Query: 192 PEIKKTSFKGDSGGPLVCNK-----VAQGIVSYGRNNGMP--PRACTKVSSFVHWIKKTM 244 + + KGDSGGPLVC G+VS+G N G P P TKV+++ WI + Sbjct: 175 YDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 234 Query: 245 KR 246 R Sbjct: 235 GR 236 >1PPF-E nrPDB Length = 218 Score = 222 bits (567), Expect = 1e-58, Method: Composition-based stats. Identities = 77/232 (33%), Positives = 111/232 (47%), Gaps = 21/232 (9%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVT----LGA 76 I+GG A+PH+ P+M L + + CG LI +FV++AAHC + LGA Sbjct: 1 IVGGRRARPHAWPFMVSLQL---RGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGA 57 Query: 77 HNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQV 136 HN+ +EPT+Q V+R Y+P N NDI++LQL A VQ +LP+ ++ Sbjct: 58 HNLSRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 116 Query: 137 KPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKK 196 G C GWG + LQE+ +TV C +C + Sbjct: 117 GNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRS---------NVCTLVRGRQA 166 Query: 197 TSFKGDSGGPLVCNKVAQGIVSY---GRNNGMPPRACTKVSSFVHWIKKTMK 245 GDSG PLVCN + GI S+ G +G+ P A V+ FV+WI ++ Sbjct: 167 GVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 218 >5UBM-A nrPDB Length = 252 Score = 221 bits (564), Expect = 2e-58, Method: Composition-based stats. Identities = 68/254 (26%), Positives = 109/254 (42%), Gaps = 36/254 (14%) Query: 20 EIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSI--NVTLGAH 77 IIGG +A + P+ + GG LI + +VLTAAH + + +G+ Sbjct: 1 RIIGGSDADIKNFPWQVFF------DNPWAGGALINEYWVLTAAHVVEGNREPTMYVGST 54 Query: 78 NI-KEQEPTQQFIPVKRPIPHPAYN-------PKNFSNDIMLLQLERKAKRTRAVQPLRL 129 ++ + + + + HP + NF NDI L++L+ K V P+ L Sbjct: 55 SVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICL 114 Query: 130 P--SNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCE--------SDLRH 179 P S+ + G ++GWG+T + + L+ ++ V RKC+ +D Sbjct: 115 PGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPVAPLRKCKEVKVEKPTADAEA 173 Query: 180 YYDSTIELCVGDPEIKKTSFKGDSGGPLVCNK-------VAQGIVSYGRNNGMPPRACTK 232 Y + +C G E S KGDSGG A G+VS+G G T+ Sbjct: 174 YVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGT-YGLYTR 231 Query: 233 VSSFVHWIKKTMKR 246 V ++V WI KTM+ Sbjct: 232 VKNYVDWIMKTMQE 245 >1YM0-A nrPDB Length = 238 Score = 221 bits (563), Expect = 3e-58, Method: Composition-based stats. Identities = 57/240 (23%), Positives = 92/240 (38%), Gaps = 17/240 (7%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSS----INVTLGA 76 I+GG EA+P+ P+ + CGG +I D +V+ AAHC +++ +G Sbjct: 1 IVGGIEARPYEFPWQVSVRRKS-SDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVGE 59 Query: 77 HNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPS-NKAQ 135 H+ +Q V + Y+P ND+ +++ V P+ P Sbjct: 60 HDSSAASTVRQTHDVDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICAPDPANDY 119 Query: 136 VKPGQTCSVAGWGQTAPLGK-HSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEI 194 V C +GWG G L+ V + + + C++ +C D Sbjct: 120 VYRKSQC--SGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYDDMICATDNTG 177 Query: 195 --KKTSFKGDSGGPLVCNK-----VAQGIVSYGRNNGM-PPRACTKVSSFVHWIKKTMKR 246 + S +GDSGGPL GIVS+G P ++V WI T+ Sbjct: 178 MTDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWGIGCASGYPGVYSRVGFHAGWITDTITN 237 >1ELV-A nrPDB Length = 333 Score = 219 bits (559), Expect = 7e-58, Method: Composition-based stats. Identities = 69/260 (26%), Positives = 111/260 (42%), Gaps = 36/260 (13%) Query: 14 PRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSI--N 71 P + IIGG +A + P+ + GG LI + +VLTAAH + Sbjct: 76 PFEEKQRIIGGSDADIKNFPWQVFF------DNPWAGGALINEYWVLTAAHVVEGNREPT 129 Query: 72 VTLGAHNI-KEQEPTQQFIPVKRPIPHPAYN-------PKNFSNDIMLLQLERKAKRTRA 123 + +G+ ++ + + + + HP + NF NDI L++L+ K Sbjct: 130 MYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLAVPEGRTNFDNDIALVRLKDPVKMGPT 189 Query: 124 VQPLRLP--SNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCE------- 174 V P+ LP S+ + G ++GWG+T + + L+ ++ V RKC+ Sbjct: 190 VSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPVAPLRKCKEVKVEKP 248 Query: 175 -SDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNK-------VAQGIVSYGRNNGMP 226 +D Y + +C G E S KGDSGG A G+VS+G G Sbjct: 249 TADAEAYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGT- 306 Query: 227 PRACTKVSSFVHWIKKTMKR 246 T+V ++V WI KTM+ Sbjct: 307 YGLYTRVKNYVDWIMKTMQE 326 >2B9L-A nrPDB Length = 394 Score = 216 bits (551), Expect = 6e-57, Method: Composition-based stats. Identities = 65/263 (24%), Positives = 111/263 (42%), Gaps = 33/263 (12%) Query: 14 PRADAGEIIGGH-EAKPHSRPYMAYLMIWD-----QKSLKRCGGFLIRDDFVLTAAHCWG 67 R +I G EA+ P+M ++ + + CGG LI VLT AHC Sbjct: 123 ERGLDFKITGQTNEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHCVN 182 Query: 68 ------SSINVTLGAHNIKEQEP--TQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAK 119 +I + G + ++ Q +++ I H +NPK ND+ LL L+R Sbjct: 183 SYQSNLDAIKIRAGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLLDRPLV 242 Query: 120 RTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLG--KHSHTLQEVKMTVQEDRKCESDL 177 + + + LP C +GWG+ ++S+ L+++++ + KC++DL Sbjct: 243 QADNIGTICLPQQSQIF-DSTECFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQADL 301 Query: 178 RH------YYDSTIELCVGDPEIKKTSFKGDSGGPLVCNK-------VAQGIVSYGRNNG 224 R+ + +C G + K + GD G PL C + GIV++G G Sbjct: 302 RNTRLGLKFVLDQTFVCAGGEQ-GKDTCTGDGGSPLFCPDPRNPSRYMQMGIVAWGIGCG 360 Query: 225 MP--PRACTKVSSFVHWIKKTMK 245 P V+ F +WI + M+ Sbjct: 361 DENVPGVYANVAHFRNWIDQEMQ 383 >4J1Y-A nrPDB Length = 397 Score = 215 bits (547), Expect = 2e-56, Method: Composition-based stats. Identities = 68/260 (26%), Positives = 110/260 (42%), Gaps = 36/260 (13%) Query: 14 PRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSI--N 71 P + IGG +A + P+ + GG LI + +VLTAAH + Sbjct: 140 PFEEKARAIGGSDADIKNFPWQVFF------DNPWAGGALINEYWVLTAAHVVEGNREPT 193 Query: 72 VTLGAHNI-KEQEPTQQFIPVKRPIPHPAYN-------PKNFSNDIMLLQLERKAKRTRA 123 + +G+ ++ + + + + HP + NF NDI L++L+ K Sbjct: 194 MYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPT 253 Query: 124 VQPLRLP--SNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCE------- 174 V P+ LP S+ + G ++GWG+T + + L+ ++ V RKC+ Sbjct: 254 VSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPVAPLRKCKEVKVEKP 312 Query: 175 -SDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNK-------VAQGIVSYGRNNGMP 226 +D Y + +C G E S KGDSGG A G+VS+G G Sbjct: 313 TADAEAYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGT- 370 Query: 227 PRACTKVSSFVHWIKKTMKR 246 T+V ++V WI KTM+ Sbjct: 371 YGLYTRVKNYVDWIMKTMQE 390 >3I77-A nrPDB Length = 230 Score = 213 bits (544), Expect = 4e-56, Method: Composition-based stats. Identities = 61/240 (25%), Positives = 99/240 (41%), Gaps = 25/240 (10%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW---GSSINVTLGAH 77 ++GG A P+M L+ ++++ CGG L D VLTAAHC G++ ++T Sbjct: 1 VVGGTRAAQGEFPFMVRLI--NEENEGFCGGALYAQDIVLTAAHCVSGSGNNTSITATGG 58 Query: 78 NIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVK 137 + Q + + + + P + + + D L++L QP+ P+ K Sbjct: 59 VVDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLA---------QPINQPTLKIATT 109 Query: 138 PGQ---TCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPE- 193 T +VAGWG G L + + D C S + +C G P+ Sbjct: 110 TAYNQGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYPDT 169 Query: 194 IKKTSFKGDSGGPLVCN-----KVAQGIVSYGRNNGMP--PRACTKVSSFVHWIKKTMKR 246 + +GDSGGP+ + GIVS+G P P T+VS+F I + Sbjct: 170 GGVDTCQGDSGGPMFRKDNADEWIQVGIVSWGYGCARPGYPGVYTEVSTFASAIASAART 229 >6BQM-A nrPDB Length = 506 Score = 212 bits (540), Expect = 1e-55, Method: Composition-based stats. Identities = 67/246 (27%), Positives = 109/246 (44%), Gaps = 26/246 (10%) Query: 18 AGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGS----SINVT 73 + IIGG +A PYM L + + CGG + +VLTAAHC +V Sbjct: 8 SSRIIGGEQATAGEWPYMVALTARNSSHV-FCGGSYLGGRYVLTAAHCVDKEDPAKGDVL 66 Query: 74 LGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNK 133 LGA ++ + T + I V++ H +Y + NDI +L+LER R+VQ + S+ Sbjct: 67 LGAFDMNDVN-TAERIHVRQIYVHNSYITASMGNDIAVLELERDPLPRRSVQ-ISDSSDF 124 Query: 134 AQVKPGQTCSVAGWGQTAP-LGKHSH---TLQEVKMTVQEDRKCE-----SDLRHYYD-- 182 ++ +V G+G G+ S L +V++ +C+ D ++ Y Sbjct: 125 NELTKDSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGSDQDAKNNYSQL 184 Query: 183 STIELCVGDPEIKKTSFKGDSGGPLVCN----KVAQGIVSYGRNNGMP--PRACTKVSSF 236 + C G K + GD+GGP+ + + G+VS+G G P T +S F Sbjct: 185 TNNAFCAG--SFGKDACSGDAGGPIFFDSNNGRKQMGVVSWGDGCGRANSPGVYTNLSVF 242 Query: 237 VHWIKK 242 W+ Sbjct: 243 NDWLDD 248 >2ASU-B nrPDB Length = 234 Score = 208 bits (530), Expect = 2e-54, Method: Composition-based stats. Identities = 70/239 (29%), Positives = 110/239 (46%), Gaps = 27/239 (11%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGS------SINVTL 74 ++GGH P + P+ L +++ CGG L+++ ++LTA C+ S V L Sbjct: 1 VVGGH---PGNSPWTVSLR--NRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWL 55 Query: 75 GA--HNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSN 132 G N + EP+ Q +PV + + P+ + ++LL+LER + V + LP Sbjct: 56 GTLFQNPQHGEPSLQRVPVAKMVCGPS------GSQLVLLKLERSVTLNQRVALICLPPE 109 Query: 133 KAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDP 192 V PG C +AGWG+T G + L + V +++C R E+C Sbjct: 110 WYVVPPGTKCEIAGWGETKGTGNDT-VLNVALLNVISNQECNIKHRGRV-RESEMCTEGL 167 Query: 193 EIKKTSFKGDSGGPLVC----NKVAQGIVSYGRNNGMP--PRACTKVSSFVHWIKKTMK 245 + +GD GGPL C + V +GI+ R P T+VS FV WI K M+ Sbjct: 168 LAPVGACEGDYGGPLACFTHNSWVLEGIIIPNRVCARSRWPAVFTRVSVFVDWIHKVMR 226 >2HLC-A nrPDB Length = 230 Score = 207 bits (528), Expect = 3e-54, Method: Composition-based stats. Identities = 68/231 (29%), Positives = 112/231 (48%), Gaps = 14/231 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLK-RCGGFLIRDDFVLTAAHCWGSSINVTLGAHNI 79 II G+EA PY A L I Q + CGG LI + ++LTAAHC +++V + + Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHDAVSVVVYLGSA 60 Query: 80 KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 + E + + +R I H +NP + ND+ L+++ + T +QP+RLPS + Sbjct: 61 VQYEG-EAVVNSERIISHSMFNPDTYLNDVALIKIPH-VEYTDNIQPIRLPSGEELNNKF 118 Query: 140 QTCS--VAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKT 197 + V+GWGQ + LQ V ++ +C + +C GD K+ Sbjct: 119 ENIWATVSGWGQ---SNTDTVILQYTYNLVIDNDRCAQEYPPGIIVESTIC-GDTSDGKS 174 Query: 198 SFKGDSGGPLVCNK--VAQGIVSYGRNNGM---PPRACTKVSSFVHWIKKT 243 GDSGGP V + + G+VS+ G P ++V+S++ WI++ Sbjct: 175 PCFGDSGGPFVLSDKNLLIGVVSFVSGAGCESGKPVGFSRVTSYMDWIQQN 225 >3BEU-A nrPDB Length = 224 Score = 207 bits (528), Expect = 3e-54, Method: Composition-based stats. Identities = 59/239 (24%), Positives = 93/239 (38%), Gaps = 29/239 (12%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW---GSSINVTLGAH 77 ++GG A P+M L + CGG L D VLTAAHC G++ ++T Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG-------CGGALYAQDIVLTAAHCVSGSGNNTSITATGG 53 Query: 78 NIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVK 137 + Q + + + + P + + + D L++L QP+ P+ K Sbjct: 54 VVDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLA---------QPINQPTLKIATT 104 Query: 138 PGQ---TCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEI 194 T +VAGWG G L + + D C S + +C G Sbjct: 105 TAYNQGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYDTK 164 Query: 195 KKTSFKGDSGGPLVCN-----KVAQGIVSYGRNNGMPP--RACTKVSSFVHWIKKTMKR 246 ++ + +GDSGGP+ V GIVS+G T+VS+F I + Sbjct: 165 QEDTCQGDSGGPMFRKDNADEWVQVGIVSWGEGCARKGKYGVYTEVSTFASAIASAART 223 >4LK4-A nrPDB Length = 357 Score = 207 bits (527), Expect = 4e-54, Method: Composition-based stats. Identities = 68/249 (27%), Positives = 111/249 (44%), Gaps = 25/249 (10%) Query: 16 ADAGEIIGGHEAKPHSRPYMAYLMIW--DQKSLKRCGGFLIRDDFVLTAAHCWGS----S 69 + II G A P + L+ D + CGG + +VLTAAHC+ S S Sbjct: 6 DISSRIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRSAAS 65 Query: 70 INVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRL 129 ++V +GA+++ ++ I ++ H +Y+P N NDI +++L + T ++ + L Sbjct: 66 VDVIIGAYDLNNSSQGER-IAAQKIYRHLSYSPSNLLNDIAIVELAQ----TSSLPAITL 120 Query: 130 --PSNKAQVKPGQTCSVAGWGQTAPLGK--HSHTLQEVKMTVQEDRKCESDLRHYYDS-- 183 P+ + + +VAGWG T + LQEV + + C+ ++H S Sbjct: 121 AGPATRTSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQHGISSDP 180 Query: 184 -TIELCVGDPEIKKTSFKGDSGGPLVCN--KVAQGIVSYGRNNGMP---PRACTKVSSFV 237 + C K S +GD+GGP+V + GIVS+G T VS F Sbjct: 181 NSTNFCAARLT--KDSCQGDAGGPIVVKTGREQLGIVSWGDEQCAKTGTYGVYTNVSYFR 238 Query: 238 HWIKKTMKR 246 WI K + Sbjct: 239 DWITKHTNQ 247 >1PQ7-A nrPDB Length = 224 Score = 206 bits (526), Expect = 5e-54, Method: Composition-based stats. Identities = 59/229 (25%), Positives = 94/229 (41%), Gaps = 16/229 (6%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG----SSINVTLGA 76 I+GG A P++ + + CGG L+ + VLTAAHC S + G+ Sbjct: 1 IVGGTSASAGDFPFIVSI---SRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQIRAGS 57 Query: 77 HNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQV 136 + T V+ HP+Y+ N ND+ +L+L + RL ++ + Sbjct: 58 LSRTSGGITSSLSSVR---VHPSYSGNN--NDLAILKLSTSIPSGGNIGYARLAASGSDP 112 Query: 137 KPGQTCSVAGWGQTAPLGKHSHT-LQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIK 195 G + +VAGWG T+ G + L +V + + C + + C G Sbjct: 113 VAGSSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCAGVSSGG 172 Query: 196 KTSFKGDSGGPLV-CNKVAQGIVSYGRNNGMPP--RACTKVSSFVHWIK 241 K S +GDSGGP+V + G VS+G P V + +I Sbjct: 173 KDSCQGDSGGPIVDSSNTLIGAVSWGNGCARPNYSGVYASVGALRSFID 221 >2FMJ-A nrPDB Length = 222 Score = 202 bits (514), Expect = 1e-52, Method: Composition-based stats. Identities = 61/239 (25%), Positives = 92/239 (38%), Gaps = 31/239 (12%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCW---GSSINVTLGAH 77 ++GG A P+M L + CGG L D VLTAAHC G++ ++T Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG-------CGGALYAQDIVLTAAHCVSGSGNNTSITATGG 53 Query: 78 NIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVK 137 + Q + + + + P YN D L++L QP+ P+ K Sbjct: 54 VVDLQSSSAVKVRSTKVLQAPGYNGT--GKDWALIKLA---------QPINQPTLKIATT 102 Query: 138 PGQ---TCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEI 194 T +VAGWG G L + + D C S + + E+C G Sbjct: 103 TAYNQGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSAYGNELVANEEICAGYDTG 162 Query: 195 KKTSFKGDSGGPLVCN-----KVAQGIVSYGRNNGMPP--RACTKVSSFVHWIKKTMKR 246 + +GDSGGP+ + GIVS+G T+VS+F I + Sbjct: 163 GVDTCQGDSGGPMFRKDNADEWIQVGIVSWGEGCARKGKYGVYTEVSTFASAIASAART 221 >1SI5-H nrPDB Length = 240 Score = 198 bits (504), Expect = 2e-51, Method: Composition-based stats. Identities = 63/242 (26%), Positives = 107/242 (44%), Gaps = 28/242 (11%) Query: 21 IIGG--HEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSS----INVTL 74 ++ G +M L ++ CGG LI++ +VLTA C+ S L Sbjct: 1 VVNGIPTRTNIG---WMVSLRYRNK---HICGGSLIKESWVLTARQCFPSRDLKDYEAWL 54 Query: 75 GAHNI--KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSN 132 G H++ + E +Q + V + + P +D++L++L R A V + LP+ Sbjct: 55 GIHDVHGRGDEKCKQVLNVSQLVYGPE------GSDLVLMKLARPAVLDDFVSTIDLPNY 108 Query: 133 KAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYD-STIELCVGD 191 + + +CSV GWG T L + L+ + + + KC R + E+C G Sbjct: 109 GSTIPEKTSCSVYGWGYTG-LINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGA 167 Query: 192 PEIKKTSFKGDSGGPLVCN----KVAQGIVSYGRNNGMP--PRACTKVSSFVHWIKKTMK 245 +I +GD GGPLVC ++ G++ GR +P P +V+ + WI K + Sbjct: 168 EKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKIIL 227 Query: 246 RY 247 Y Sbjct: 228 TY 229 >1M9U-A nrPDB Length = 241 Score = 196 bits (499), Expect = 8e-51, Method: Composition-based stats. Identities = 65/241 (26%), Positives = 95/241 (39%), Gaps = 19/241 (7%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG----SSINVTLGA 76 +IGG A P P+ CG L+ L+A+HC ++I V G Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAGL 60 Query: 77 HNIKEQEPTQQFIPVKRPIPHPAYNPKN--FSNDIMLLQLERKAKRTRAVQPLRLPSNKA 134 + T Q V H Y +SNDI +L L +Q LP+N Sbjct: 61 WQQSDTSGT-QTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANNN 119 Query: 135 QVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTI---ELCVGD 191 G TC ++GWG+T LQ+ + V +C + + + I +CV D Sbjct: 120 NDYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVGGANIWDNHICVQD 179 Query: 192 PEIKKTSFKGDSGGPLVCNK---VAQGIVSY----GRNNGMP--PRACTKVSSFVHWIKK 242 P + GDSGGPL C G+ S+ G +P P T+VS+++ WI Sbjct: 180 PAGNTGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGACLPDYPSVYTRVSAYLGWIGD 239 Query: 243 T 243 Sbjct: 240 N 240 >4X0L-C nrPDB Length = 259 Score = 196 bits (498), Expect = 1e-50, Method: Composition-based stats. Identities = 57/254 (22%), Positives = 101/254 (39%), Gaps = 36/254 (14%) Query: 20 EIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAH--CWGSSINVTLG-- 75 I+GGH S P+ A ++ G LI + ++LT A S N T Sbjct: 14 RILGGHLDAKGSFPWQAKMV---SHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDI 70 Query: 76 AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ 135 A + +Q + +++ + HP Y+ DI L++L++K V P+ LPS Sbjct: 71 APTLTLYVGKKQLVEIEKVVLHPNYS----QVDIGLIKLKQKVSVNERVMPICLPSKDYA 126 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHY--------------- 180 + G+ V+GWG+ A K + L+ V + V + +C Sbjct: 127 -EVGRVGYVSGWGRNANF-KFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQ 184 Query: 181 -YDSTIELCVGDPEIKKTSFKGDSGGPLVCN------KVAQGIVSYGRNNG-MPPRACTK 232 + C G + ++ + GD+G + A GI+S+ ++ K Sbjct: 185 PILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAEYGVYVK 244 Query: 233 VSSFVHWIKKTMKR 246 V+S W++KT+ Sbjct: 245 VTSIQDWVQKTIAE 258 >4WJG-C nrPDB Length = 315 Score = 195 bits (496), Expect = 2e-50, Method: Composition-based stats. Identities = 57/254 (22%), Positives = 101/254 (39%), Gaps = 36/254 (14%) Query: 20 EIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAH--CWGSSINVTLG-- 75 I+GGH S P+ A ++ G LI + ++LT A S N T Sbjct: 70 RILGGHLDAKGSFPWQAKMV---SHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDI 126 Query: 76 AHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ 135 A + +Q + +++ + HP Y+ DI L++L++K V P+ LPS Sbjct: 127 APTLTLYVGKKQLVEIEKVVLHPNYS----QVDIGLIKLKQKVSVNERVMPICLPSKDYA 182 Query: 136 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHY--------------- 180 + G+ V+GWG+ A K + L+ V + V + +C Sbjct: 183 -EVGRVGYVSGWGRNANF-KFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQ 240 Query: 181 -YDSTIELCVGDPEIKKTSFKGDSGGPLVCN------KVAQGIVSYGRNNG-MPPRACTK 232 + C G + ++ + GD+G + A GI+S+ ++ K Sbjct: 241 PILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAEYGVYVK 300 Query: 233 VSSFVHWIKKTMKR 246 V+S W++KT+ Sbjct: 301 VTSIQDWVQKTIAE 314 >4F4O-C nrPDB Length = 347 Score = 194 bits (493), Expect = 3e-50, Method: Composition-based stats. Identities = 59/264 (22%), Positives = 103/264 (39%), Gaps = 48/264 (18%) Query: 14 PRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVT 73 P I+GG S P+ A ++ + G LI + ++LT A N+ Sbjct: 96 PVDQVQRIMGGSLDAKGSFPWQAKMISHHNLTS---GATLINEQWLLTTAK------NLR 146 Query: 74 LGAHN----------IKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRA 123 LG N ++ +Q + +++ I HP N + DI L++L++K Sbjct: 147 LGHKNDTKAKDIAPTLRLYVGKKQEVEIEKVIFHP----DNSTVDIGLIKLKQKVPVNER 202 Query: 124 VQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHY--- 180 V P+ LPS V G V+GWG+ A L + L+ V + V + KC Sbjct: 203 VMPICLPSKDY-VNVGLVGYVSGWGRNANLN-FTEHLKYVMLPVADQEKCVQYYEGSTVP 260 Query: 181 -------------YDSTIELCVGDPEIKKTSFKGDSGGPLVCN------KVAQGIVSYGR 221 + C G + ++ + GD+G + A GI+S+ + Sbjct: 261 EKKTPKSPVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKDDDTWYAAGILSFDK 320 Query: 222 NNGM-PPRACTKVSSFVHWIKKTM 244 + +V+S + WI+ T+ Sbjct: 321 SCRTAEYGVYVRVTSILDWIQTTI 344 >5XW8-A nrPDB Length = 133 Score = 193 bits (492), Expect = 5e-50, Method: Composition-based stats. Identities = 52/139 (37%), Positives = 69/139 (49%), Gaps = 6/139 (4%) Query: 13 LPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINV 72 P D +I+GG+ +S PY L CGG LI +V++AAHC+ S I V Sbjct: 1 FPTDDDDKIVGGYTCAANSIPYQVSL----NSGSHFCGGSLINSQWVVSAAHCYKSRIQV 56 Query: 73 TLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSN 132 LG HNI E +QFI + I HP +N NDIML++L A V + LP + Sbjct: 57 RLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRS 116 Query: 133 KAQVKPGQTCSVAGWGQTA 151 A G C ++GWG T Sbjct: 117 CA--AAGTECLISGWGNTK 133 >3H7O-A nrPDB Length = 228 Score = 191 bits (486), Expect = 2e-49, Method: Composition-based stats. Identities = 58/229 (25%), Positives = 95/229 (41%), Gaps = 8/229 (3%) Query: 23 GGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSI--NVTLGAHNIK 80 GG + P+ + + + CGG ++ FVLTAAHC + + + Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTN 61 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKR-TRAVQPLRLPSNKAQVKPG 139 E + P + Y + NDI +L+L R K +P +LP + + K G Sbjct: 62 LWEDPGKSDPYVSHVYLSFYRQETMENDIAILELSRPLKLDGLKSKPAKLPDIEFRPKTG 121 Query: 140 QTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 199 V+G+G + H L+ ++TV + +C + + S C + S Sbjct: 122 SDVLVSGYGDGQTMDPKDHDLKSAQLTVVDLDECRTKYGPIFLSLQVFCAQKVGVSLES- 180 Query: 200 KGDSGGPLVCNKVAQGIVSY--GRNNGMPPRACTKVSSFVHWIKKTMKR 246 GD+G P V G+ +Y R G P TKV S+V WI+ +K+ Sbjct: 181 -GDAGDPTVQQDTLVGVAAYFPKRPEGA-PEVFTKVGSYVSWIQDIIKK 227 >3H7T-A nrPDB Length = 235 Score = 191 bits (485), Expect = 3e-49, Method: Composition-based stats. Identities = 55/231 (23%), Positives = 91/231 (39%), Gaps = 10/231 (4%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 IIGG ++ P+ +++ CGG ++ +FV+TAA C + + H Sbjct: 1 IIGGKKSDITKEPWAVGVLVD---EKPFCGGSILTANFVITAAQCVDGTKPSDISIHYGS 57 Query: 81 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTR-AVQPLRLPSNKAQVKPG 139 T+ + + I Y+P N+ +++ E K + + LPS +P Sbjct: 58 SYRTTKGTSVMAKKIYIVRYHPLTMQNNYAVIETEMPIKLDDKTTKKIELPSLLYDPEPD 117 Query: 140 QTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHY----YDSTIELCVGDPEI 194 + V+GWG T ++S L E TV + + CE + Y C G Sbjct: 118 TSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGVFCAGGEYD 177 Query: 195 KKTSFKGDSGGPLVCNKVAQGIVSY-GRNNGMPPRACTKVSSFVHWIKKTM 244 + GD+G P V N G+ SY P +V +V IK + Sbjct: 178 ETYIGYGDAGDPAVQNGTLVGVASYISSMPSEFPSVFLRVGYYVLDIKDII 228 >2PKA-B nrPDB Length = 152 Score = 177 bits (450), Expect = 3e-45, Method: Composition-based stats. Identities = 50/152 (32%), Positives = 81/152 (53%), Gaps = 9/152 (5%) Query: 101 NPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLG---KHS 157 + K++S+D+MLL+L+ AK T AV+ L LP+ + ++ G TC +GWG P + Sbjct: 2 DGKDYSHDLMLLRLQSPAKITDAVKVLELPTQEPEL--GSTCEASGWGSIEPGPDDFEFP 59 Query: 158 HTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGIV 217 +Q V++T+ ++ C ++ LC G K + GDSGGPL+CN + QGI Sbjct: 60 DEIQCVQLTLLQNTFCADAHPDKVTESM-LCAGYLPGGKDTCMGDSGGPLICNGMWQGIT 118 Query: 218 SYG---RNNGMPPRACTKVSSFVHWIKKTMKR 246 S+G + P TK+ ++ WI T+ Sbjct: 119 SWGHTPCGSANKPSIYTKLIFYLDWIDDTITE 150 >3VGC-B nrPDB Length = 131 Score = 167 bits (424), Expect = 4e-42, Method: Composition-based stats. Identities = 43/132 (32%), Positives = 64/132 (48%), Gaps = 3/132 (2%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTL-GAHNI 79 I+ G EA P S P+ L D+ CGG LI +++V+TAAHC ++ +V + G + Sbjct: 1 IVNGEEAVPGSWPWQVSLQ--DKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQ 58 Query: 80 KEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 139 Q + + + + YN +NDI LL+L A ++ V + LPS G Sbjct: 59 GSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAAG 118 Query: 140 QTCSVAGWGQTA 151 TC GWG T Sbjct: 119 TTCVTTGWGLTR 130 >2JET-B nrPDB Length = 128 Score = 164 bits (417), Expect = 2e-41, Method: Composition-based stats. Identities = 42/129 (32%), Positives = 64/129 (49%), Gaps = 3/129 (2%) Query: 24 GHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTL-GAHNIKEQ 82 G +A P S P+ L D+ CGG LI +D+V+TAAHC + +V + G + Sbjct: 1 GEDAIPGSWPWQVSLQ--DKTGFHFCGGSLISEDWVVTAAHCGVKTSDVVVAGEFDQGSD 58 Query: 83 EPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQTC 142 E Q + + + +P +N NDI LL+L A+ + V + LP+ PG C Sbjct: 59 EENIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDFPPGTVC 118 Query: 143 SVAGWGQTA 151 + GWG+T Sbjct: 119 ATTGWGKTK 127 >1RIW-B nrPDB Length = 147 Score = 161 bits (407), Expect = 4e-40, Method: Composition-based stats. Identities = 41/148 (27%), Positives = 65/148 (43%), Gaps = 16/148 (10%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-----WGSSIN---- 71 I+ G +A+ P+ L + L CG LI D +VLTAAHC W + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 59 Query: 72 -VTLGAHNIKEQEPTQQFIPV-KRPIPHPAYNP-KNFSNDIMLLQLERKAKRTRAVQPLR 128 V +G H+ E + I + ++ HP YN +N DI L++L++ + + P+ Sbjct: 60 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 119 Query: 129 LPSNKAQ---VKPGQTCSVAGWGQTAPL 153 LP + ++ G V GWG Sbjct: 120 LPDRETAASLLQAGYKGRVTGWGNLKET 147 >1BBR-H nrPDB Length = 150 Score = 154 bits (391), Expect = 2e-38, Method: Composition-based stats. Identities = 44/151 (29%), Positives = 64/151 (42%), Gaps = 16/151 (10%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-----WGSSIN---- 71 I+ G +A+ P+ L + L CG LI D +VLTAAHC W + Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTVDDL 59 Query: 72 -VTLGAHNIKEQEPTQQFIPV-KRPIPHPAYNP-KNFSNDIMLLQLERKAKRTRAVQPLR 128 V +G H+ E + I + + HP YN +N DI LL+L+R + + + P+ Sbjct: 60 LVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVC 119 Query: 129 LPSNKAQVK---PGQTCSVAGWGQTAPLGKH 156 LP + K G V GWG Sbjct: 120 LPDKQTAAKLLHAGFKGRVTGWGNRRETWTT 150 >1AKS-B nrPDB Length = 98 Score = 140 bits (353), Expect = 7e-34, Method: Composition-based stats. Identities = 34/96 (35%), Positives = 51/96 (53%), Gaps = 3/96 (3%) Query: 151 APLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCN 210 + + LQ +K V + C+S + +CVG + K S +GDSGGP+VCN Sbjct: 1 SSGSSYPSLLQCLKAPVLSNSSCKSSYPGQITGNM-ICVGFLQGGKDSCQGDSGGPVVCN 59 Query: 211 KVAQGIVSYGRNNGM--PPRACTKVSSFVHWIKKTM 244 QGIVS+G P TKV ++V+WI++T+ Sbjct: 60 GQLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQTI 95 >2WIN-I nrPDB Length = 507 Score = 138 bits (347), Expect = 3e-33, Method: Composition-based stats. Identities = 56/235 (23%), Positives = 100/235 (42%), Gaps = 49/235 (20%) Query: 30 HSRPYMAYL-MIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIKEQEPTQQF 88 H +P+ A + +I K + C G ++ + FVLTAAHC+ V H+IK ++ Sbjct: 232 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF----TVDDKEHSIKVSVGGEKR 287 Query: 89 -IPVKRPIPHPAYN---------PKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ--- 135 + ++ + HP YN P+ + D+ L++L+ K K + ++P+ LP + Sbjct: 288 DLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRA 347 Query: 136 --VKPGQTCSVAGWGQTAPLGKHSHTL----------QEVKMTVQEDR-KCESDLRHYYD 182 + P TC + P +EV + + + CE D ++ Sbjct: 348 LRLPPTTTCQQQK-EELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYAPG 406 Query: 183 -----------STIELCVGD--PEIKKTSFKGDSGGPLVCNK----VAQGIVSYG 220 + LC G P + +GDSGGPL+ +K + G++S+G Sbjct: 407 YDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 461 >1DLE-A nrPDB Length = 298 Score = 135 bits (341), Expect = 1e-32, Method: Composition-based stats. Identities = 56/235 (23%), Positives = 100/235 (42%), Gaps = 49/235 (20%) Query: 30 HSRPYMAYL-MIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIKEQEPTQQF 88 H +P+ A + +I K + C G ++ + FVLTAAHC+ V H+IK ++ Sbjct: 25 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF----TVDDKEHSIKVSVGGEKR 80 Query: 89 -IPVKRPIPHPAYN---------PKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ--- 135 + ++ + HP YN P+ + D+ L++L+ K K + ++P+ LP + Sbjct: 81 DLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRA 140 Query: 136 --VKPGQTCSVAGWGQTAPLGKHSHTL----------QEVKMTVQEDR-KCESDLRHYYD 182 + P TC + P +EV + + + CE D ++ Sbjct: 141 LRLPPTTTCQQQK-EELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYAPG 199 Query: 183 -----------STIELCVGD--PEIKKTSFKGDSGGPLVCNK----VAQGIVSYG 220 + LC G P + +GDSGGPL+ +K + G++S+G Sbjct: 200 YDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 254 >2OK5-A nrPDB Length = 752 Score = 134 bits (337), Expect = 4e-32, Method: Composition-based stats. Identities = 56/235 (23%), Positives = 100/235 (42%), Gaps = 49/235 (20%) Query: 30 HSRPYMAYL-MIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIKEQEPTQQF 88 H +P+ A + +I K + C G ++ + FVLTAAHC+ V H+IK ++ Sbjct: 476 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF----TVDDKEHSIKVSVGGEKR 531 Query: 89 -IPVKRPIPHPAYN---------PKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ--- 135 + ++ + HP YN P+ + D+ L++L+ K K + ++P+ LP + Sbjct: 532 DLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRA 591 Query: 136 --VKPGQTCSVAGWGQTAPLGKHSHTL----------QEVKMTVQEDR-KCESDLRHYYD 182 + P TC + P +EV + + + CE D ++ Sbjct: 592 LRLPPTTTCQQQK-EELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYAPG 650 Query: 183 -----------STIELCVGD--PEIKKTSFKGDSGGPLVCNK----VAQGIVSYG 220 + LC G P + +GDSGGPL+ +K + G++S+G Sbjct: 651 YDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 705 >2KAI-A nrPDB Length = 80 Score = 120 bits (302), Expect = 5e-28, Method: Composition-based stats. Identities = 33/81 (40%), Positives = 43/81 (53%), Gaps = 3/81 (3%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 80 IIGG E + +S P+ + + CGG L+ +VLTAAHC + V LG HN+ Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQ---CGGVLVNPKWVLTAAHCKNDNYEVWLGRHNLF 57 Query: 81 EQEPTQQFIPVKRPIPHPAYN 101 E E T QF V PHP +N Sbjct: 58 ENENTAQFFGVTADFPHPGFN 78 >1EPT-B nrPDB Length = 82 Score = 114 bits (286), Expect = 3e-26, Method: Composition-based stats. Identities = 33/84 (39%), Positives = 42/84 (50%), Gaps = 2/84 (2%) Query: 68 SSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPL 127 S I V LG HNI E +QFI + I HP +N NDIML++L A V + Sbjct: 1 SRIQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATV 60 Query: 128 RLPSNKAQVKPGQTCSVAGWGQTA 151 LP + A G C ++GWG T Sbjct: 61 SLPRSCA--AAGTECLISGWGNTK 82 >2HNT-F nrPDB Length = 105 Score = 111 bits (277), Expect = 4e-25, Method: Composition-based stats. Identities = 25/103 (24%), Positives = 37/103 (35%), Gaps = 12/103 (11%) Query: 156 HSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGD---PEIKKTSFKGDSGGPLVCN-- 210 LQ V + + E C+ R + C G + + +GDSGGP V Sbjct: 2 QPSVLQVVNLPIVERPVCKDSTRIRITDNM-FCAGYKPDEGKRGDACEGDSGGPFVMKSP 60 Query: 211 ----KVAQGIVSYGRNNGM--PPRACTKVSSFVHWIKKTMKRY 247 GIVS+G T V WI+K + ++ Sbjct: 61 FNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQF 103 >1BBR-E nrPDB Length = 109 Score = 109 bits (274), Expect = 8e-25, Method: Composition-based stats. Identities = 26/102 (25%), Positives = 37/102 (36%), Gaps = 12/102 (11%) Query: 156 HSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGD---PEIKKTSFKGDSGGPLVCN-- 210 LQ V + + E C++ R + C G + + +GDSGGP V Sbjct: 6 QPSVLQVVNLPLVERPVCKASTRIRITDNM-FCAGYKPGEGKRGDACEGDSGGPFVMKSP 64 Query: 211 ----KVAQGIVSYGRNNGM--PPRACTKVSSFVHWIKKTMKR 246 GIVS+G T V WI+K + R Sbjct: 65 YNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDR 106 >2I6S-A nrPDB Length = 517 Score = 109 bits (273), Expect = 1e-24, Method: Composition-based stats. Identities = 48/230 (20%), Positives = 83/230 (36%), Gaps = 50/230 (21%) Query: 33 PYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIKE-QEPTQQFIPV 91 P+ + KS + C G LI D +VLTAAHC+ + +L N+ + + + + Sbjct: 244 PWHVTI---KPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEFLI 300 Query: 92 KRPIPHPAYNPKNFSN---------DIMLLQLERKAKRTRAVQPLRLPSNKAQV-----K 137 ++ + P ++ N DI LL+L +K K + +P+ LP Sbjct: 301 EKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRP 360 Query: 138 PGQTCSVAGWGQTAPLGKHSHTLQ--------EVKMTV---QEDRKCESDLR-------- 178 G TC L ++ + + E C + Sbjct: 361 QGSTCR----DHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPN 416 Query: 179 ----HYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNK----VAQGIVSYG 220 + LC G E ++ KG+SGG + + G+VS+G Sbjct: 417 LTDVREVVTDQFLCSGTQED-ESPCKGESGGAVFLERRFRFFQVGLVSWG 465 >3RU4-E nrPDB Length = 96 Score = 97.9 bits (243), Expect = 3e-21, Method: Composition-based stats. Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 9/96 (9%) Query: 155 KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCN---- 210 LQ+ + + + C+ +C G +S GDSGGPLVC Sbjct: 1 NTPDRLQQASLPLLSNTNCKK-YWGTKIKDAMICAGAS--GVSSCMGDSGGPLVCKKNGA 57 Query: 211 KVAQGIVSYGRNNG--MPPRACTKVSSFVHWIKKTM 244 GIVS+G + P +V++ V+W+++T+ Sbjct: 58 WTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTL 93 >2JET-C nrPDB Length = 99 Score = 97.9 bits (243), Expect = 4e-21, Method: Composition-based stats. Identities = 24/97 (24%), Positives = 41/97 (42%), Gaps = 9/97 (9%) Query: 155 KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCN---- 210 K LQ+ + + + C+ + C G S GDSGGPLVC Sbjct: 4 KTPEKLQQAALPIVSEADCKKSWGSKITDVMT-CAGAS--GVDSCMGDSGGPLVCQKDGV 60 Query: 211 KVAQGIVSYGRNNG--MPPRACTKVSSFVHWIKKTMK 245 GIVS+G P ++V++ + W+++ ++ Sbjct: 61 WTLAGIVSWGSGVCSTSTPGVYSRVTALMPWVQQILE 97 >3F1S-B nrPDB Length = 283 Score = 97.2 bits (241), Expect = 6e-21, Method: Composition-based stats. Identities = 54/238 (22%), Positives = 84/238 (35%), Gaps = 53/238 (22%) Query: 33 PYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAH-NIKEQEPTQQFIPV 91 P+ L + + CGG +IR++FVLT A C N+T+ + N Q+P I + Sbjct: 65 PWQVKL--TNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDP--LMIKI 120 Query: 92 KRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ---VKPGQTCSVAGWG 148 H Y+ ND+ LL+LE + A P+ P + P ++GW Sbjct: 121 THVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWA 180 Query: 149 QT-----APLGKHSHTL-------QEVKMTVQEDRKCESDLR---HYYDSTIELCVGDPE 193 + L TL Q + +TV CE H+ D ++ Sbjct: 181 RNGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSV-----VTR 235 Query: 194 IKKTSFKGDSGGPLVCNKVAQGIVSYGRNNGMPP-------RACTKVSSFVHWIKKTM 244 + S G++ G P TKVS + W K+ M Sbjct: 236 EHRGS------------WFLTGVL------GSQPVGGQAHMVLVTKVSRYSLWFKQIM 275 >3H5C-B nrPDB Length = 317 Score = 94.9 bits (235), Expect = 3e-20, Method: Composition-based stats. Identities = 53/232 (22%), Positives = 83/232 (35%), Gaps = 41/232 (17%) Query: 33 PYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAH-NIKEQEPTQQFIPV 91 P+ L + + CGG +IR++FVLT A C N+T+ + N Q+P I + Sbjct: 106 PWQVKL--TNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDP--LMIKI 161 Query: 92 KRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ---VKPGQTCSVAGWG 148 H Y+ ND+ LL+LE + A P+ P + P ++GW Sbjct: 162 THVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWA 221 Query: 149 QT-----APLGKHSHTL-------QEVKMTVQEDRKCESDLR---HYYDSTIELCVGDPE 193 + L TL Q + +TV CE H+ D ++ Sbjct: 222 RNGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSV-----VTR 276 Query: 194 IKKTSFKGDSGGPLVCNKVAQGIVSYGRNNGMPPRA-CTKVSSFVHWIKKTM 244 + S G++ G TKVS + W K+ M Sbjct: 277 EHRGS------------WFLTGVLGSQPVGGQAHMVLVTKVSRYSLWFKQIM 316 >2HNT-E nrPDB Length = 81 Score = 82.9 bits (204), Expect = 1e-16, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 33/72 (45%), Gaps = 4/72 (5%) Query: 86 QQFIPVKRPIPHPAYNP-KNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ---VKPGQT 141 ++ +++ HP YN +N DI L++L++ + + P+ LP + ++ G Sbjct: 3 EKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYK 62 Query: 142 CSVAGWGQTAPL 153 V GWG Sbjct: 63 GRVTGWGNLKET 74 >2HNT-C nrPDB Length = 70 Score = 81.0 bits (199), Expect = 4e-16, Method: Composition-based stats. Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 11/71 (15%) Query: 21 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHC-----WGSSIN---- 71 I+ G +A+ P+ L + L CG LI D +VLTAAHC W + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQEL-LCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 59 Query: 72 -VTLGAHNIKE 81 V +G H+ Sbjct: 60 LVRIGKHSRTR 70 >1P3E-A nrPDB Length = 215 Score = 42.1 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 17/112 (15%), Positives = 35/112 (31%), Gaps = 16/112 (14%) Query: 45 SLKRCGGFLIRDDFVLTAAHC--------WGSSINVTLGAHNIKEQEPTQQFIPVKRPIP 96 C G LI + +LT HC + + +V G ++ + + Sbjct: 28 GGSSCTGTLIAPNKILTNGHCVYNTASRSYSAKGSVYPGMNDSTAVNGSA---NMTEFYV 84 Query: 97 HPAY-NPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQTCSVAGW 147 Y N D +++ + V + + G T ++G+ Sbjct: 85 PSGYINTGASQYDFAVIKTDT--NIGNTVGYRSI--RQVTNLTGTTIKISGY 132 >2EA3-A nrPDB Length = 189 Score = 37.1 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 12/28 (42%), Positives = 14/28 (50%) Query: 201 GDSGGPLVCNKVAQGIVSYGRNNGMPPR 228 GDSGG L+ AQG+ S G N Sbjct: 135 GDSGGSLLAGNQAQGVTSGGSGNCRTGG 162 >2PFE-A nrPDB Length = 186 Score = 36.3 bits (83), Expect = 0.011, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 17/37 (45%), Gaps = 2/37 (5%) Query: 195 KKTSF--KGDSGGPLVCNKVAQGIVSYGRNNGMPPRA 229 + T+ GDSGGP + AQG+ S G + Sbjct: 130 RTTACAEGGDSGGPWLTGSQAQGVTSGGTGDCRSGGI 166 >2OUA-A nrPDB Length = 188 Score = 35.5 bits (81), Expect = 0.020, Method: Composition-based stats. Identities = 30/183 (16%), Positives = 46/183 (25%), Gaps = 59/183 (32%) Query: 60 LTAAHCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAK 119 +TA HC V++G + + + P ND ++ Sbjct: 31 VTAGHCGSVGTQVSIG---------NGRGVFERSVFP---------GNDAAFVRGTSNFT 72 Query: 120 RTRAV--------QPLRLPSNKAQVKPGQ----TCSVAGW--GQTAPLGKHSHTLQEVKM 165 T V + S + G + S GW G + Q Sbjct: 73 LTNLVSRYNSGGYATV---SGSSTAPIGSQVCRSGSTTGWYCGTIQARNQTVSYPQGTVH 129 Query: 166 TVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNNGM 225 ++ C GDSGG + AQG+ S G N Sbjct: 130 SLTRTSVCAEP------------------------GDSGGSFISGTQAQGVTSGGSGNCR 165 Query: 226 PPR 228 Sbjct: 166 TGG 168 >2SFA-A nrPDB Length = 191 Score = 34.0 bits (77), Expect = 0.058, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 12/28 (42%) Query: 201 GDSGGPLVCNKVAQGIVSYGRNNGMPPR 228 GDSGG L A G+ S G N Sbjct: 145 GDSGGALFAGSTALGLTSGGSGNCRTGG 172 >5JYK-A nrPDB Length = 566 Score = 34.0 bits (77), Expect = 0.063, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 33/110 (30%), Gaps = 22/110 (20%) Query: 31 SRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIKEQEPTQQFIP 90 S P+ S GF+I VLT AH V L K T+ Sbjct: 115 SLPWQRKRQYSSGSS-----GFIIGGRRVLTNAHSVEHHTQVKL----KKRGSDTKYLAT 165 Query: 91 VKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLR---LPSNKAQVK 137 V DI LL + + V P+ LP+ + V Sbjct: 166 VLAI---------GTECDIALLTVTDD-EFWEGVSPVEFGDLPALQDAVT 205 >5ILA-A nrPDB Length = 301 Score = 32.8 bits (74), Expect = 0.12, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 33/110 (30%), Gaps = 22/110 (20%) Query: 31 SRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIKEQEPTQQFIP 90 S P+ S GF+I VLT AH V L K T+ Sbjct: 115 SLPWQRKRQYSSGSS-----GFIIGGRRVLTNAHSVEHHTQVKL----KKRGSDTKYLAT 165 Query: 91 VKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLR---LPSNKAQVK 137 V DI LL + + V P+ LP+ + V Sbjct: 166 VLAI---------GTECDIALLTVTDD-EFWEGVSPVEFGDLPALQDAVT 205 >5ILB-A nrPDB Length = 474 Score = 32.8 bits (74), Expect = 0.12, Method: Composition-based stats. Identities = 20/89 (22%), Positives = 32/89 (35%), Gaps = 20/89 (22%) Query: 25 HEAKPHSRPYMAYLMIWDQKSLKRCG-GFLIRDDFVLTAAHCWGSSINVTLGAHNIKEQE 83 H A +S P+ Q+ G F+I D +LT AHC V + ++ Sbjct: 17 HTAPDYSLPWQ------KQRQFTSTGSAFMIGDGKLLTNAHCVEHDTQVKV------KRR 64 Query: 84 PTQQFIPVKRPIPHPAYNPKNFSNDIMLL 112 + V + + + DI LL Sbjct: 65 GDDRKY-VAKVLV------RGVDCDIALL 86 >4FLN-A nrPDB Length = 539 Score = 32.8 bits (74), Expect = 0.12, Method: Composition-based stats. Identities = 20/89 (22%), Positives = 32/89 (35%), Gaps = 20/89 (22%) Query: 25 HEAKPHSRPYMAYLMIWDQKSLKRCG-GFLIRDDFVLTAAHCWGSSINVTLGAHNIKEQE 83 H A +S P+ Q+ G F+I D +LT AHC V + ++ Sbjct: 57 HTAPDYSLPWQ------KQRQFTSTGSAFMIGDGKLLTNAHCVEHDTQVKV------KRR 104 Query: 84 PTQQFIPVKRPIPHPAYNPKNFSNDIMLL 112 + V + + + DI LL Sbjct: 105 GDDRKY-VAKVLV------RGVDCDIALL 126 >2SGA-A nrPDB Length = 181 Score = 32.5 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 12/28 (42%) Query: 201 GDSGGPLVCNKVAQGIVSYGRNNGMPPR 228 GDSGG L A G+ S G N Sbjct: 135 GDSGGSLFAGSTALGLTSGGSGNCRTGG 162 >3LT3-A nrPDB Length = 217 Score = 32.1 bits (72), Expect = 0.20, Method: Composition-based stats. Identities = 40/171 (23%), Positives = 63/171 (36%), Gaps = 33/171 (19%) Query: 51 GFLIRDDFVLTAAHCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIM 110 GF+I D V+T AH S NVT+ A + P + + +Y+P S D+ Sbjct: 42 GFVISPDRVMTNAHVVAGSNNVTVYAGDK----------PFEATVV--SYDP---SVDVA 86 Query: 111 LLQLERKAKRTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQED 170 +L A PL + A K G V G+ ++E + + Sbjct: 87 IL-----AVPHLPPPPLVFAAEPA--KTGADVVVLGYPGGGNFTATPARIREA-IRL--- 135 Query: 171 RKCESDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLV-CNKVAQGIVSYG 220 Y + I+ +GD+GGPL+ N G+V +G Sbjct: 136 -----SGPDIYGDPEPVTRDVYTIRADVEQGDAGGPLIDLNGQVLGVV-FG 180 >1DUE-A nrPDB Length = 242 Score = 31.3 bits (70), Expect = 0.37, Method: Composition-based stats. Identities = 19/108 (17%), Positives = 34/108 (31%), Gaps = 16/108 (14%) Query: 51 GFLIRDDFVLTAAHC--------WGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNP 102 G LI + VLT H S ++ + E VK + P Sbjct: 59 GVLIGKNTVLTNRHIAKFANGDPSKVSFRPSINTDDNGNTETPYGEYEVKEILQEP---- 114 Query: 103 KNFSNDIMLLQLERK---AKRTRAVQPLRLPSNKAQVKPGQTCSVAGW 147 D+ L++L+ + P ++ +K G + G+ Sbjct: 115 FGAGVDLALIRLKPDQNGVSLGDKISPAKI-GTSNDLKDGDKLELIGY 161 >4V1Y-A nrPDB Length = 494 Score = 30.9 bits (69), Expect = 0.55, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 22/59 (37%), Gaps = 6/59 (10%) Query: 54 IRDDFVLTAAHCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAY-NPKNFSNDIML 111 + D +V H I V LG H P + I + + P + N N I+L Sbjct: 41 LGDSWV----HVQDGRI-VALGVHAESVPPPADRVIDARGKVVLPGFINAHTHVNQILL 94 >2HRV-A nrPDB Length = 142 Score = 30.5 bits (68), Expect = 0.68, Method: Composition-based stats. Identities = 17/57 (29%), Positives = 24/57 (42%), Gaps = 4/57 (7%) Query: 165 MTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFK-GDSGGPLVCNKVAQGIVSYG 220 +TV E YY I+ + I + + GD GG L+C GIV+ G Sbjct: 70 ITVTSHDWYEIQESEYYPKHIQY---NLLIGEGPCEPGDCGGKLLCKHGVIGIVTAG 123 >3W95-A nrPDB Length = 171 Score = 29.8 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 17/46 (36%), Positives = 19/46 (41%), Gaps = 6/46 (13%) Query: 177 LRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRN 222 Y S + L G E GD+GG L C GIVS G N Sbjct: 111 YPARYQSHLMLAQGHSEP------GDAGGILRCQHGVVGIVSTGGN 150 >4FVB-A nrPDB Length = 152 Score = 29.8 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 17/46 (36%), Positives = 19/46 (41%), Gaps = 6/46 (13%) Query: 177 LRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRN 222 Y S + L G E GD+GG L C GIVS G N Sbjct: 92 YPARYQSHLMLAQGHSEP------GDAGGILRCQHGVVGIVSTGGN 131 >4NCX-A nrPDB Length = 506 Score = 29.8 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 9/38 (23%), Positives = 19/38 (50%) Query: 109 IMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQTCSVAG 146 + L Q + + A++PL +P ++ + P C +G Sbjct: 456 LSLNQTNSETTLSGAMKPLCIPLDQPPMPPNMKCFWSG 493 >3H7V-A nrPDB Length = 330 Score = 29.0 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 26/89 (29%), Gaps = 12/89 (13%) Query: 60 LTAAH-CWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKA 118 LT A W S + L E Q + P P + + + DI L Q + Sbjct: 16 LTTAQGVWRSRSGIYL------RLEDEQGQVGYGEIAPLPGWGSETLNADIALCQ-QLPG 68 Query: 119 KRTRAVQPLRLPSNKAQVKPGQTCSVAGW 147 T + + + Q W Sbjct: 69 HLTPEIM----ATIPEALPAAQFGFATAW 93 >1HPG-A nrPDB Length = 187 Score = 29.0 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 13/31 (41%), Gaps = 2/31 (6%) Query: 195 KKTSFK--GDSGGPLVCNKVAQGIVSYGRNN 223 + T+ GDSGG VA GI S Sbjct: 133 RTTACSAGGDSGGAHFAGSVALGIHSGSSGC 163 >6HQA-B nrPDB Length = 722 Score = 29.0 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 14/51 (27%), Positives = 26/51 (50%), Gaps = 1/51 (1%) Query: 83 EPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNK 133 +P+ + P K +P P + ++ NDI ++Q + +AK + LPS Sbjct: 333 DPSDENNPSKDTLPLPLKSAQDLRNDIAMIQ-DSRAKIKLSAAQASLPSVC 382 >1U1U-A nrPDB Length = 765 Score = 28.6 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 11/33 (33%), Gaps = 3/33 (9%) Query: 203 SGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSS 235 SG N Q SYG PP VS Sbjct: 505 SGFAFTANGWVQ---SYGSRCVKPPVIYGDVSR 534 >5XIP-A nrPDB Length = 498 Score = 28.2 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 8/27 (29%), Positives = 14/27 (51%) Query: 120 RTRAVQPLRLPSNKAQVKPGQTCSVAG 146 T A++PL +P ++ + G C G Sbjct: 459 MTGAMKPLCIPFDQPPMPEGTRCFFTG 485 >4NSY-A nrPDB Length = 275 Score = 28.2 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 8/35 (22%), Positives = 15/35 (42%), Gaps = 6/35 (17%) Query: 37 YLMIWDQKSLKRCGGFLIRDD------FVLTAAHC 65 + + ++ C G L+ + + LTA HC Sbjct: 24 SVAAYSKQGTMWCTGSLVNNSANDKKMYFLTANHC 58 >4XZB-A nrPDB Length = 314 Score = 27.8 bits (61), Expect = 4.1, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 14/32 (43%) Query: 133 KAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVK 164 A ++ G V+ WG + G L+E + Sbjct: 218 DAALQAGTPVFVSEWGTSDASGDGGPYLEEAE 249 >4A8B-A nrPDB Length = 436 Score = 27.4 bits (60), Expect = 6.1, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 32/74 (43%), Gaps = 16/74 (21%) Query: 51 GFLIRDD--FVLTAAHCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSND 108 G +I +VLT H + +++ ++ +E + + I + +D Sbjct: 67 GVIINASKGYVLTNNHVINQAQKISIQLNDGREFD--------AKLI------GSDDQSD 112 Query: 109 IMLLQLERKAKRTR 122 I LLQ++ +K T+ Sbjct: 113 IALLQIQNPSKLTQ 126 >3STJ-A nrPDB Length = 345 Score = 27.4 bits (60), Expect = 6.1, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 32/74 (43%), Gaps = 16/74 (21%) Query: 51 GFLIRDD--FVLTAAHCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSND 108 G +I +VLT H + +++ ++ +E + + I + +D Sbjct: 67 GVIINASKGYVLTNNHVINQAQKISIQLNDGREFD--------AKLI------GSDDQSD 112 Query: 109 IMLLQLERKAKRTR 122 I LLQ++ +K T+ Sbjct: 113 IALLQIQNPSKLTQ 126 >3STI-A nrPDB Length = 245 Score = 27.4 bits (60), Expect = 6.1, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 32/74 (43%), Gaps = 16/74 (21%) Query: 51 GFLIRDD--FVLTAAHCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSND 108 G +I +VLT H + +++ ++ +E + + I + +D Sbjct: 67 GVIINASKGYVLTNNHVINQAQKISIQLNDGREFD--------AKLI------GSDDQSD 112 Query: 109 IMLLQLERKAKRTR 122 I LLQ++ +K T+ Sbjct: 113 IALLQIQNPSKLTQ 126 >3MH6-A nrPDB Length = 456 Score = 27.1 bits (59), Expect = 6.6, Method: Composition-based stats. Identities = 35/172 (20%), Positives = 57/172 (33%), Gaps = 43/172 (25%) Query: 51 GFLIRDD--FVLTAAHCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSND 108 G +I D +V+T H + A IK Q + K +P++ D Sbjct: 90 GVIIDADKGYVVTNNHVVDN-------ATVIKVQLSDGRKFDAKMV----GKDPRS---D 135 Query: 109 IMLLQLERKAKRTRAVQPL---RLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKM 165 I L+Q++ T A++ L V G G G+T G S + Sbjct: 136 IALIQIQNPKNLT-AIKMADSDALRVGDYTVAIGNPF---GLGETVTSGIVSALGRSGLN 191 Query: 166 TVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLV-CNKVAQGI 216 + ++ + + +G+SGG LV N GI Sbjct: 192 --------AENYENFIQTDAAIN-----------RGNSGGALVNLNGELIGI 224 >3COS-A nrPDB Length = 381 Score = 27.1 bits (59), Expect = 7.0, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 34/82 (41%), Gaps = 19/82 (23%) Query: 82 QEPTQQFIPVKRPIPH----PAYNPKNFSNDIMLLQLERKAKRTRAVQPLRL-------- 129 ++ T +F +P+ H ++ +DI L +++ A R + L Sbjct: 131 EDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLER----VCLLGCGFSTG 186 Query: 130 ---PSNKAQVKPGQTCSVAGWG 148 N A+V PG TC+V G G Sbjct: 187 YGAAINNAKVTPGSTCAVFGLG 208 >2M5T-A nrPDB Length = 142 Score = 27.1 bits (59), Expect = 8.5, Method: Composition-based stats. Identities = 9/27 (33%), Positives = 14/27 (51%), Gaps = 1/27 (3%) Query: 195 KKTSFK-GDSGGPLVCNKVAQGIVSYG 220 + GD+GG L+C GI++ G Sbjct: 96 GEGPCVPGDAGGKLLCRHGVIGIITAG 122 >1CDO-A nrPDB Length = 374 Score = 26.7 bits (58), Expect = 8.6, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 24/65 (36%), Gaps = 15/65 (23%) Query: 98 PAYNPKNFSNDIMLLQLERKAKRTRAVQPLRL-----------PSNKAQVKPGQTCSVAG 146 ++ N I + +++ A + L N A+V+PG TC+V G Sbjct: 145 STFSQYTVVNQIAVAKIDPSAPLD----TVCLLGCGVSTGFGAAVNTAKVEPGSTCAVFG 200 Query: 147 WGQTA 151 G Sbjct: 201 LGAVG 205 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.162 0.598 Lambda K H 0.267 0.0498 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,898,974 Number of Sequences: 36641 Number of extensions: 534221 Number of successful extensions: 2547 Number of sequences better than 10.0: 202 Number of HSP's better than 10.0 without gapping: 325 Number of HSP's successfully gapped in prelim test: 39 Number of HSP's that attempted gapping in prelim test: 999 Number of HSP's gapped (non-prelim): 375 length of query: 247 length of database: 10,336,785 effective HSP length: 95 effective length of query: 152 effective length of database: 6,855,890 effective search space: 1042095280 effective search space used: 1042095280 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 58 (26.7 bits)