BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P0CY27 (391 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2QZW-A nrPDB 686 0.0 3PVK-A nrPDB 503 e-143 2H6T-A nrPDB 479 e-135 2QZX-A nrPDB 407 e-114 1J71-A nrPDB 348 2e-96 3FV3-A nrPDB 310 8e-85 4Y9W-A nrPDB 303 6e-83 1PSO-E nrPDB 115 3e-26 1UH8-A nrPDB 112 3e-25 2PSG-A nrPDB 111 5e-25 4PEP-A nrPDB 110 8e-25 1AM5-A nrPDB 107 7e-24 1TZS-A nrPDB 107 1e-23 4CMS-A nrPDB 105 3e-23 1FMX-A nrPDB 105 4e-23 5BWY-A nrPDB 103 1e-22 1XDH-A nrPDB 103 2e-22 2BJU-A nrPDB 102 2e-22 4AA9-A nrPDB 102 2e-22 1MIQ-A nrPDB 100 1e-21 2ASI-A nrPDB 99 2e-21 2ANL-A nrPDB 99 3e-21 1QS8-A nrPDB 98 6e-21 5JOD-A nrPDB 98 7e-21 5I70-B nrPDB 98 7e-21 5MKT-A nrPDB 97 2e-20 5UX4-A nrPDB 96 2e-20 1AVF-A nrPDB 96 3e-20 5N71-A nrPDB 96 3e-20 1SMR-A nrPDB 95 4e-20 3QS1-A nrPDB 91 7e-19 1MPP-A nrPDB 88 8e-18 3FNT-A nrPDB 86 2e-17 1B5F-A nrPDB 86 4e-17 5MLG-A nrPDB 85 5e-17 3QVI-A nrPDB 85 5e-17 5NFG-A nrPDB 82 5e-16 5HCT-A nrPDB 80 1e-15 3PI0-A nrPDB 80 1e-15 3VCM-A nrPDB 79 3e-15 4AMT-A nrPDB 79 4e-15 1PPK-E nrPDB 76 3e-14 1IBQ-A nrPDB 74 8e-14 1IZE-A nrPDB 72 5e-13 1QDM-A nrPDB 71 6e-13 3EMY-A nrPDB 62 3e-10 1WKR-A nrPDB 62 3e-10 3O9L-A nrPDB 62 5e-10 3TPL-A nrPDB 54 1e-07 4OC6-B nrPDB 54 2e-07 4OD9-A nrPDB 49 6e-06 4B1C-A nrPDB 45 5e-05 3ZKX-A nrPDB 43 3e-04 4ZL4-A nrPDB 35 0.059 5G5H-C nrPDB 30 1.4 3CP8-A nrPDB 30 2.5 3LIZ-A nrPDB 29 2.8 4WAD-A nrPDB 29 3.4 3FG6-A nrPDB 28 5.1 6BYQ-A nrPDB 28 5.1 5UOG-A nrPDB 28 5.2 1LPA-B nrPDB 28 6.7 3OAD-B nrPDB 28 6.9 3K10-A nrPDB 28 8.4 1HPL-A nrPDB 28 8.7 5MYJ-A nrPDB 28 9.2 4WJ3-M nrPDB 28 9.6 5MP7-A nrPDB 28 9.9 >2QZW-A nrPDB Length = 341 Score = 686 bits (1770), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/341 (100%), Positives = 341/341 (100%) Query: 51 QAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCK 110 QAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCK Sbjct: 1 QAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCK 60 Query: 111 GKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP 170 GKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP Sbjct: 61 GKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP 120 Query: 171 QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYS 230 QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYS Sbjct: 121 QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYS 180 Query: 231 GSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAE 290 GSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAE Sbjct: 181 GSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAE 240 Query: 291 LKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGIS 350 LKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGIS Sbjct: 241 LKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGIS 300 Query: 351 DANILGDNFLRSAYLVYDLDDDKISLAQVKYTSASNIAALT 391 DANILGDNFLRSAYLVYDLDDDKISLAQVKYTSASNIAALT Sbjct: 301 DANILGDNFLRSAYLVYDLDDDKISLAQVKYTSASNIAALT 341 >3PVK-A nrPDB Length = 342 Score = 503 bits (1294), Expect = e-143, Method: Compositional matrix adjust. Identities = 253/342 (73%), Positives = 281/342 (82%), Gaps = 1/342 (0%) Query: 51 QAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCK 110 QA+PVTL+NE V+YAADIT+GSN QK NVIVDTGSSDLWVPD +V C Q+ADFCK Sbjct: 1 QAVPVTLHNEQVTYAADITVGSNNQKLNVIVDTGSSDLWVPDVNVDCQVTYSDQTADFCK 60 Query: 111 GKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP 170 KG Y P S+ SQ+L TPF IGYGDGSSSQGTLYKDTVGFGG SI QV AD+ TSI Sbjct: 61 QKGTYDPSGSSASQDLNTPFKIGYGDGSSSQGTLYKDTVGFGGVSIKNQVLADVDSTSID 120 Query: 171 QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYS 230 QGILG+GYKTNEA G YDNVPVTLK QGVIAKNAYSLYLNSP+AATGQIIFGGVD AKYS Sbjct: 121 QGILGVGYKTNEAGGSYDNVPVTLKKQGVIAKNAYSLYLNSPDAATGQIIFGGVDNAKYS 180 Query: 231 GSLIAVPVTSDRELRITLNSLKAVGKNIN-GNIDVLLDSGTTITYLQQDVAQDIIDAFQA 289 GSLIA+PVTSDRELRI+L S++ GK IN N+DVLLDSGTTITYLQQD+A II AF Sbjct: 181 GSLIALPVTSDRELRISLGSVEVSGKTINTDNVDVLLDSGTTITYLQQDLADQIIKAFNG 240 Query: 290 ELKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGI 349 +L D G++FY DC SG V FNF NAKISVPASEF A L +GQPY KCQLL + Sbjct: 241 KLTQDSNGNSFYEVDCNLSGDVVFNFSKNAKISVPASEFAASLQGDDGQPYDKCQLLFDV 300 Query: 350 SDANILGDNFLRSAYLVYDLDDDKISLAQVKYTSASNIAALT 391 +DANILGDNFLRSAY+VYDLDD++ISLAQVKYTSAS+I+ALT Sbjct: 301 NDANILGDNFLRSAYIVYDLDDNEISLAQVKYTSASSISALT 342 >2H6T-A nrPDB Length = 340 Score = 479 bits (1232), Expect = e-135, Method: Compositional matrix adjust. Identities = 239/341 (70%), Positives = 282/341 (82%), Gaps = 1/341 (0%) Query: 51 QAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCK 110 Q +PV L NE VSYA+DIT+GSNKQK V++DTGSSDLWVPD+ V+C + GQ +FCK Sbjct: 1 QTVPVKLINEQVSYASDITVGSNKQKLTVVIDTGSSDLWVPDSQVSC-QAGQGQDPNFCK 59 Query: 111 GKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP 170 +G Y+P SS++SQNL +PF I YGDG++SQGT YKDT+GFGG SITKQ FAD+T TS+ Sbjct: 60 NEGTYSPSSSSSSQNLNSPFSIEYGDGTTSQGTWYKDTIGFGGISITKQQFADVTSTSVD 119 Query: 171 QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYS 230 QGILGIGYKT+EA G+YDNVPVTLKNQG+I+KNAYSLYLNS A +GQIIFGGVD AKYS Sbjct: 120 QGILGIGYKTHEAEGNYDNVPVTLKNQGIISKNAYSLYLNSRQATSGQIIFGGVDNAKYS 179 Query: 231 GSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAE 290 G+LIA+PVTSD ELRI LN++K G++IN ++DVLLDSGTTITYLQQ VA +I AF + Sbjct: 180 GTLIALPVTSDNELRIHLNTVKVAGQSINADVDVLLDSGTTITYLQQGVADQVISAFNGQ 239 Query: 291 LKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGIS 350 D G+ FY+ DC SG+VDF FD NAKISVPASEFTAPL +GQ Y +CQLL G S Sbjct: 240 ETYDANGNLFYLVDCNLSGSVDFAFDKNAKISVPASEFTAPLYTEDGQVYDQCQLLFGTS 299 Query: 351 DANILGDNFLRSAYLVYDLDDDKISLAQVKYTSASNIAALT 391 D NILGDNFLRSAY+VYDLDD++ISLAQVKYT+ASNIAALT Sbjct: 300 DYNILGDNFLRSAYIVYDLDDNEISLAQVKYTTASNIAALT 340 >2QZX-A nrPDB Length = 342 Score = 407 bits (1047), Expect = e-114, Method: Compositional matrix adjust. Identities = 196/339 (57%), Positives = 258/339 (76%), Gaps = 1/339 (0%) Query: 53 IPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGK 112 + VTL+NE ++Y ADIT+GS+ QK NVIVDTGSSDLW+PD++V C G DFCK Sbjct: 3 VAVTLHNEAITYTADITVGSDNQKLNVIVDTGSSDLWIPDSNVICIPKWRGDKGDFCKSA 62 Query: 113 GIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIPQG 172 G Y+P SS TSQNL T F I YGDGS ++G LYKDTVG GG S+ Q+FA++ TS +G Sbjct: 63 GSYSPASSRTSQNLNTRFDIKYGDGSYAKGKLYKDTVGIGGVSVRDQLFANVWSTSARKG 122 Query: 173 ILGIGYKTNEAAG-DYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSG 231 ILGIG+++ EA DYDN+P++L+NQG+I K AYSLYLNS A+TGQIIFGG+DKAKYSG Sbjct: 123 ILGIGFQSGEATEFDYDNLPISLRNQGIIGKAAYSLYLNSAEASTGQIIFGGIDKAKYSG 182 Query: 232 SLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAEL 291 SL+ +P+TS+++L + L S+ G+N++ N +VLLDSGTTI+Y + + ++I+ A A++ Sbjct: 183 SLVDLPITSEKKLTVGLRSVNVRGRNVDANTNVLLDSGTTISYFTRSIVRNILYAIGAQM 242 Query: 292 KSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGISD 351 K D G+ YV DC+TSGT+DF F NN KISVP SEF Y +G+P+PKC++ + S+ Sbjct: 243 KFDSAGNKVYVADCKTSGTIDFQFGNNLKISVPVSEFLFQTYYTSGKPFPKCEVRIRESE 302 Query: 352 ANILGDNFLRSAYLVYDLDDDKISLAQVKYTSASNIAAL 390 NILGDNFLRSAY+VY+LDD KIS+A VKYTS S+I A+ Sbjct: 303 DNILGDNFLRSAYVVYNLDDKKISMAPVKYTSESDIVAI 341 >1J71-A nrPDB Length = 334 Score = 348 bits (893), Expect = 2e-96, Method: Compositional matrix adjust. Identities = 187/339 (55%), Positives = 232/339 (68%), Gaps = 8/339 (2%) Query: 53 IPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGK 112 +P TL NE SYAADI +GSN+QK V++DTGSSDLWV D C GQ+ +FCK + Sbjct: 3 VPTTLINEGPSYAADIVVGSNQQKQTVVIDTGSSDLWVVDTDAECQVTYSGQTNNFCKQE 62 Query: 113 GIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIPQG 172 G + P SS+++QNL F I YGD +SSQG+ YKDTVGFGG SI Q FAD+T TS+ QG Sbjct: 63 GTFDPSSSSSAQNLNQDFSIEYGDLTSSQGSFYKDTVGFGGISIKNQQFADVTTTSVDQG 122 Query: 173 ILGIGYKTNEAAGD-YDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSG 231 I+GIG+ +EA + YDNVPVTLK QG+I KNAYSLYLNS +A+TG+IIFGGVD AKY+G Sbjct: 123 IMGIGFTADEAGYNLYDNVPVTLKKQGIINKNAYSLYLNSEDASTGKIIFGGVDNAKYTG 182 Query: 232 SLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAEL 291 +L A+PVTS ELR+ L S+ G +++ N DV+LDSGTTITY Q A A Sbjct: 183 TLTALPVTSSVELRVHLGSINFDGTSVSTNADVVLDSGTTITYFSQSTADKFARIVGATW 242 Query: 292 KSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGISD 351 D + + + C SG FNFD KI+VP SE S ++ C + +D Sbjct: 243 --DSRNEIYRLPSCDLSGDAVFNFDQGVKITVPLSELILKDSDSS-----ICYFGISRND 295 Query: 352 ANILGDNFLRSAYLVYDLDDDKISLAQVKYTSASNIAAL 390 ANILGDNFLR AY+VYDLDD ISLAQVKYTS+S+I+AL Sbjct: 296 ANILGDNFLRRAYIVYDLDDKTISLAQVKYTSSSDISAL 334 >3FV3-A nrPDB Length = 339 Score = 310 bits (794), Expect = 8e-85, Method: Compositional matrix adjust. Identities = 182/350 (52%), Positives = 225/350 (64%), Gaps = 23/350 (6%) Query: 52 AIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKG 111 +I ++L NE SYA+ +++GSNKQ+ VI+DTGSSD WV D++ C G+ D CK Sbjct: 2 SISLSLINEGPSYASKVSVGSNKQQQTVIIDTGSSDFWVVDSNAQC-----GKGVD-CKS 55 Query: 112 KGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIPQ 171 G +TP SS++ +NLG F I YGDGS+SQGT KDTV G SIT Q AD+T+TS+ Q Sbjct: 56 SGTFTPSSSSSYKNLGAAFTIRYGDGSTSQGTWGKDTVTINGVSITGQQIADVTQTSVDQ 115 Query: 172 GILGIGYKTNEAAGD---------YDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFG 222 GILGIGY +NEA D YDNVPVTLK QG I NAYSLYLNSP+A TG IIFG Sbjct: 116 GILGIGYTSNEAVYDTSGRQTTPNYDNVPVTLKKQGKIRTNAYSLYLNSPSAETGTIIFG 175 Query: 223 GVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQD 282 GVD AKYSG L+A VTS + L I+L S+ G + + LLDSGTT+TY D A Sbjct: 176 GVDNAKYSGKLVAEQVTSSQALTISLASVNLKGSSFSFGDGALLDSGTTLTYFPSDFAAQ 235 Query: 283 IIDAFQAELKSDGQGHTFYVTDCQ--TSGTVDFNFDNNAKISVPASEFTAPLSYANGQPY 340 + D A L + Y DC TSGT FNF N AKI+VP +E+ Y NG Sbjct: 236 LADKAGARLVQVARDQYLYFIDCNTDTSGTTVFNFGNGAKITVPNTEYV----YQNGD-- 289 Query: 341 PKCQLLLGISDANILGDNFLRSAYLVYDLDDDKISLAQVKYTSASNIAAL 390 C + SD ILGDNFLR AYL+Y+LD + IS+AQVKYT+ S+I+A+ Sbjct: 290 GTCLWGIQPSDDTILGDNFLRHAYLLYNLDANTISIAQVKYTTDSSISAV 339 >4Y9W-A nrPDB Length = 334 Score = 303 bits (777), Expect = 6e-83, Method: Compositional matrix adjust. Identities = 175/338 (51%), Positives = 217/338 (64%), Gaps = 20/338 (5%) Query: 60 EHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKS 119 E SY +++GSNKQ+ V++DTGSSD WV D+S +C K CK G + P S Sbjct: 10 EGPSYGIRVSVGSNKQEQQVVLDTGSSDFWVVDSSASCQKGN-------CKQYGTFDPHS 62 Query: 120 STTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIPQGILGIGYK 179 ST+ ++LG+ F IGYGD SSS GT +DT+ GG SIT Q FAD+T TS+ QGILG+G Sbjct: 63 STSFKSLGSSFSIGYGDKSSSIGTWGQDTIYLGGTSITNQRFADVTSTSVNQGILGVGRV 122 Query: 180 TNEAAGD-YDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSGSLIAVPV 238 E+A YDNVP+TLK QG I NAYSLYLNSP AATG IIFGGVD AKYSG LI P+ Sbjct: 123 ETESANPPYDNVPITLKKQGKIKTNAYSLYLNSPGAATGTIIFGGVDNAKYSGKLIEEPL 182 Query: 239 TSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAELKSDGQGH 298 SDR L + L SL G N N V++DSGTTI+YL + D+ + A L+ G G+ Sbjct: 183 VSDRYLAVNLKSLNYNGDNSNAGFGVVVDSGTTISYLPDSIVDDLANKVGAYLEPVGLGN 242 Query: 299 TFYVTDCQTS--GTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGISDAN--- 353 Y DC + G+ F FDN AKI+VP SEF S AN C L SD Sbjct: 243 ELYFIDCNANPQGSASFTFDNGAKITVPLSEFVLQ-STANA-----CVWGLQSSDRQNVP 296 Query: 354 -ILGDNFLRSAYLVYDLDDDKISLAQVKYTSASNIAAL 390 ILGDNFLR AY+V++LD + +SLAQVKYTSAS+++A+ Sbjct: 297 PILGDNFLRHAYVVFNLDKETVSLAQVKYTSASSVSAI 334 >1PSO-E nrPDB Length = 326 Score = 115 bits (288), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 105/337 (31%), Positives = 164/337 (48%), Gaps = 34/337 (10%) Query: 58 NNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTP 117 N + Y I IG+ Q F V+ DTGSS+LWVP SV C S+ C + P Sbjct: 8 NYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVP--SVYC-------SSLACTNHNRFNP 58 Query: 118 KSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTS-------IP 170 + S+T Q+ I YG GS + G L DTV GG S T Q+F +++T P Sbjct: 59 EDSSTYQSTSETVSITYGTGSMT-GILGYDTVQVGGISDTNQIFG-LSETEPGSFLYYAP 116 Query: 171 -QGILGIGYKTNEAAGD---YDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDK 226 GILG+ Y + ++G +DN+ NQG+++++ +S+YL++ + + +IFGG+D Sbjct: 117 FDGILGLAYPSISSSGATPVFDNI----WNQGLVSQDLFSVYLSADDQSGSVVIFGGIDS 172 Query: 227 AKYSGSLIAVPVTSDRELRITLNSLKAVGKNING--NIDVLLDSGTTITYLQQDVAQDII 284 + Y+GSL VPVT + +IT++S+ G+ I ++D+GT++ +I Sbjct: 173 SYYTGSLNWVPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIANIQ 232 Query: 285 DAFQAELKSDGQGHTFYVTDCQT-SGTVDFNFD-NNAKISVPASEFTAPLSYANGQPYPK 342 A SDG V C S D F N + VP S + + + Sbjct: 233 SDIGASENSDGD----MVVSCSAISSLPDIVFTINGVQYPVPPSAYILQSEGSCISGFQG 288 Query: 343 CQLLLGISDANILGDNFLRSAYLVYDLDDDKISLAQV 379 L + ILGD F+R + V+D ++++ LA V Sbjct: 289 MNLPTESGELWILGDVFIRQYFTVFDRANNQVGLAPV 325 >1UH8-A nrPDB Length = 325 Score = 112 bits (280), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 104/337 (30%), Positives = 155/337 (45%), Gaps = 29/337 (8%) Query: 53 IPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGK 112 +P+T + Y +TIG+ +KFN+ DTGSSDLW+ AS C Q+ Sbjct: 6 VPMTDYGNDIEYYGQVTIGTPGKKFNLDFDTGSSDLWI--ASTLCTNCGSRQTK------ 57 Query: 113 GIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP-- 170 Y P S+T Q G + I YGDGSS+ G L KD V GG I Q + + Sbjct: 58 --YDPNQSSTYQADGRTWSISYGDGSSASGILAKDNVNLGGLLIKGQTIELAKREAASFA 115 Query: 171 ----QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYL-NSPNAATGQIIFGGVD 225 G+LG+G+ T L +QG+I++ + +YL + N G+ IFGG D Sbjct: 116 SGPNDGLLGLGFDTITTVRGVKTPMDNLISQGLISRPIFGVYLGKAKNGGGGEYIFGGYD 175 Query: 226 KAKYSGSLIAVPVTSDRELR-ITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDII 284 K+ GSL VP+ + R IT++ + + D +LD+GTT+ L ++A + Sbjct: 176 STKFKGSLTTVPIDNSRGWWGITVDRATVGTSTVASSFDGILDTGTTLLILPNNIAASVA 235 Query: 285 DAFQAELKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQ 344 A+ A DG Y C TS F N AS +P S + +C Sbjct: 236 RAYGASDNGDGT----YTISCDTSRFKPLVFSING-----ASFQVSPDSLVFEEFQGQCI 286 Query: 345 LLLGIS--DANILGDNFLRSAYLVYDLDDDKISLAQV 379 G D I+GD FL++ Y+V++ ++ +A V Sbjct: 287 AGFGYGNWDFAIIGDTFLKNNYVVFNQGVPEVQIAPV 323 >2PSG-A nrPDB Length = 370 Score = 111 bits (278), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 102/331 (30%), Positives = 163/331 (49%), Gaps = 34/331 (10%) Query: 64 YAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTTS 123 Y I IG+ Q F VI DTGSS+LWVP SV C S+ C + P S+T Sbjct: 58 YFGTIGIGTPAQDFTVIFDTGSSNLWVP--SVYC-------SSLACSDHNQFNPDDSSTF 108 Query: 124 QNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTS-------IP-QGILG 175 + I YG GS + G L DTV GG S T Q+F +++T P GILG Sbjct: 109 EATSQELSITYGTGSMT-GILGYDTVQVGGISDTNQIFG-LSETEPGSFLYYAPFDGILG 166 Query: 176 IGYKTNEAAGD---YDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSGS 232 + Y + A+G +DN L +QG+++++ +S+YL+S + + ++ GG+D + Y+GS Sbjct: 167 LAYPSISASGATPVFDN----LWDQGLVSQDLFSVYLSSNDDSGSVVLLGGIDSSYYTGS 222 Query: 233 LIAVPVTSDRELRITLNSLKAVGKNI--NGNIDVLLDSGTTITYLQQDVAQDIIDAFQAE 290 L VPV+ + +ITL+S+ G+ I +G ++D+GT++ +I A Sbjct: 223 LNWVPVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGAS 282 Query: 291 LKSDGQGHTFYVTDCQTSGTV-DFNFD-NNAKISVPASEFTAPLSYANGQPYPKCQLLLG 348 SDG+ V C + ++ D F + + + S + + + + Sbjct: 283 ENSDGE----MVISCSSIDSLPDIVFTIDGVQYPLSPSAYILQDDDSCTSGFEGMDVPTS 338 Query: 349 ISDANILGDNFLRSAYLVYDLDDDKISLAQV 379 + ILGD F+R Y V+D ++K+ LA V Sbjct: 339 SGELWILGDVFIRQYYTVFDRANNKVGLAPV 369 >4PEP-A nrPDB Length = 326 Score = 110 bits (276), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 103/337 (30%), Positives = 164/337 (48%), Gaps = 34/337 (10%) Query: 58 NNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTP 117 N Y I IG+ Q F VI DTGSS+LWVP SV C S+ C + P Sbjct: 8 NYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVP--SVYC-------SSLACSDHNQFNP 58 Query: 118 KSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTS-------IP 170 S+T + I YG GS + G L DTV GG S T Q+F +++T P Sbjct: 59 DDSSTFEATSQELSITYGTGSMT-GILGYDTVQVGGISDTNQIFG-LSETEPGSFLYYAP 116 Query: 171 -QGILGIGYKTNEAAGD---YDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDK 226 GILG+ Y + A+G +DN L +QG+++++ +S+YL+S + + ++ GG+D Sbjct: 117 FDGILGLAYPSISASGATPVFDN----LWDQGLVSQDLFSVYLSSNDDSGSVVLLGGIDS 172 Query: 227 AKYSGSLIAVPVTSDRELRITLNSLKAVGKNI--NGNIDVLLDSGTTITYLQQDVAQDII 284 + Y+GSL VPV+ + +ITL+S+ G+ I +G ++D+GT++ +I Sbjct: 173 SYYTGSLNWVPVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQ 232 Query: 285 DAFQAELKSDGQGHTFYVTDCQTSGTV-DFNFD-NNAKISVPASEFTAPLSYANGQPYPK 342 A SDG+ V C + ++ D F + + + S + + + Sbjct: 233 SDIGASENSDGE----MVISCSSIDSLPDIVFTIDGVQYPLSPSAYILQDDDSCTSGFEG 288 Query: 343 CQLLLGISDANILGDNFLRSAYLVYDLDDDKISLAQV 379 + + ILGD F+R Y V+D ++K+ LA V Sbjct: 289 MDVPTSSGELWILGDVFIRQYYTVFDRANNKVGLAPV 325 >1AM5-A nrPDB Length = 324 Score = 107 bits (268), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 100/340 (29%), Positives = 157/340 (46%), Gaps = 46/340 (13%) Query: 58 NNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTP 117 N Y I+IG+ + F VI DTGSS+LWV +S C SA C + P Sbjct: 8 NEADTEYYGVISIGTPPESFKVIFDTGSSNLWV--SSSHC-------SAQACSNHNKFKP 58 Query: 118 KSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP------- 170 + S+T G + YG G +G L +DTV GG S Q + P Sbjct: 59 RQSSTYVETGKTVDLTYGTGGM-RGILGQDTVSVGGGSDPNQELGESQTEPGPFQAAAPF 117 Query: 171 QGILGIGYKTNEAAGDYDNVPV--TLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAK 228 GILG+ Y + AAG VPV + +Q ++ K+ +S YL+ A +++ GGVD + Sbjct: 118 DGILGLAYPSIAAAGA---VPVFDNMGSQSLVEKDLFSFYLSGGGANGSEVMLGGVDNSH 174 Query: 229 YSGSLIAVPVTSDRELRITLNSLKAVGKNINGN-IDVLLDSGTTITYLQQDVAQDIIDAF 287 Y+GS+ +PVT+++ ++ L+ + G+ ++D+GT+ +I+ Sbjct: 175 YTGSIHWIPVTAEKYWQVALDGITVNGQTAACEGCQAIVDTGTSKIVAPVSALANIMKDI 234 Query: 288 QAELKSDGQGHTFYVTDCQTSGTV-DFNFD-NNAKISVPASEFTAPLSYANG-QPYPKCQ 344 A S+ QG + +C + ++ D F N K +P P +Y G Q + C Sbjct: 235 GA---SENQGEM--MGNCASVQSLPDITFTINGVKQPLP------PSAYIEGDQAF--CT 281 Query: 345 LLLG-------ISDANILGDNFLRSAYLVYDLDDDKISLA 377 LG S+ I GD FLR+ Y +YD ++K+ A Sbjct: 282 SGLGSSGVPSNTSELWIFGDVFLRNYYTIYDRTNNKVGFA 321 >1TZS-A nrPDB Length = 351 Score = 107 bits (266), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 104/345 (30%), Positives = 161/345 (46%), Gaps = 47/345 (13%) Query: 57 LNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYT 116 +N + Y I+IGS Q F VI DTGSS+LWVP SV C P CK + Sbjct: 18 INYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVP--SVYCTSPA-------CKTHSRFQ 68 Query: 117 PKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIPQ----- 171 P S+T G F I YG GS S G + D V G ++ Q F + + T Q Sbjct: 69 PSQSSTYSQPGQSFSIQYGTGSLS-GIIGADQVSVEGLTVVGQQFGE-SVTEPGQTFVDA 126 Query: 172 ---GILGIGYKTNEAAG---DYDNVPVTLKNQGVIAKNAYSLYLNS-PNAATG-QIIFGG 223 GILG+GY + G +DN + Q ++ +S+Y++S P G ++IFGG Sbjct: 127 EFDGILGLGYPSLAVGGVTPVFDN----MMAQNLVDLPMFSVYMSSNPEGGAGSELIFGG 182 Query: 224 VDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNI--NGNIDVLLDSGTTITYLQQDVAQ 281 D + +SGSL VPVT +I L++++ G + + ++D+GT++ D + Sbjct: 183 YDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIK 242 Query: 282 DIIDAFQAELKSDGQGHTFYVTDCQTSGTV-DFNFD-NNAKISVPASEFTAPLSYANGQP 339 + +A A DG+ Y +C + D F N ++ + +T L + +G Sbjct: 243 QLQNAIGAA-PVDGE----YAVECANLNVMPDVTFTINGVPYTLSPTAYTL-LDFVDGMQ 296 Query: 340 YPKCQLLLGISDAN-------ILGDNFLRSAYLVYDLDDDKISLA 377 + C D + ILGD F+R Y V+D ++++ LA Sbjct: 297 F--CSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLA 339 >4CMS-A nrPDB Length = 323 Score = 105 bits (262), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 102/353 (28%), Positives = 162/353 (45%), Gaps = 62/353 (17%) Query: 52 AIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKG 111 ++P+T N Y I +G+ Q+F V+ DTGSSD WVP S+ C ++ CK Sbjct: 5 SVPLT-NYLDSQYFGKIYLGTPPQEFTVLFDTGSSDFWVP--SIYC-------KSNACKN 54 Query: 112 KGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGG-------ASITKQVFADI 164 + P+ S+T QNLG P I YG G S QG L DTV ++ Q D+ Sbjct: 55 HQRFDPRKSSTFQNLGKPLSIHYGTG-SMQGILGYDTVTVSNIVDIQQTVGLSTQEPGDV 113 Query: 165 TKTSIPQGILGIGYKTNEAAGDYDNVPV--TLKNQGVIAKNAYSLYLNSPNAATGQIIFG 222 + GILG+ Y + A +Y ++PV + N+ ++A++ +S+Y++ N + G Sbjct: 114 FTYAEFDGILGMAYPS--LASEY-SIPVFDNMMNRHLVAQDLFSVYMDR-NGQESMLTLG 169 Query: 223 GVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNI--NGNIDVLLDSGTTITYLQQDVA 280 +D + Y+GSL VPVT + + T++S+ G + G +LD+GT+ + Sbjct: 170 AIDPSYYTGSLHWVPVTVQQYWQFTVDSVTISGVVVACEGGCQAILDTGTSKLV---GPS 226 Query: 281 QDIIDAFQAELKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPY 340 DI++ QA + Q G D + DN + + E NG+ Y Sbjct: 227 SDILNIQQAIGATQNQ-----------YGEFDIDCDNLSYMPTVVFEI-------NGKMY 268 Query: 341 P----------KCQLLLGISDAN-----ILGDNFLRSAYLVYDLDDDKISLAQ 378 P + G N ILGD F+R Y V+D ++ + LA+ Sbjct: 269 PLTPSAYTSQDQGFCTSGFQSENHSQKWILGDVFIREYYSVFDRANNLVGLAK 321 >1FMX-A nrPDB Length = 329 Score = 105 bits (261), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 104/346 (30%), Positives = 161/346 (46%), Gaps = 43/346 (12%) Query: 53 IPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGK 112 +P+T N + Y DIT+G+ Q F VI+DTGSS+LWVP S C G A F K Sbjct: 5 VPLT-NYLNAQYYTDITLGTPPQNFKVILDTGSSNLWVP--SNEC-----GSLACFLHSK 56 Query: 113 GIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP-- 170 Y ++S++ + GT F I YG G S +G + +DT+ G +I KQ FA+ TS P Sbjct: 57 --YDHEASSSYKANGTEFAIQYGTG-SLEGYISQDTLSIGDLTIPKQDFAE--ATSEPGL 111 Query: 171 -------QGILGIGYKTNEAAGDYDNVPVTLKN---QGVIAKNAYSLYLNSPNAAT---G 217 GILG+GY T D V N Q ++ + ++ YL + T G Sbjct: 112 TFAFGKFDGILGLGYDTISV----DKVVPPFYNAIQQDLLDEKRFAFYLGDTSKDTENGG 167 Query: 218 QIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNIN--GNIDVLLDSGTTITYL 275 + FGG+D++K+ G + +PV + + +G + +D+GT++ L Sbjct: 168 EATFGGIDESKFKGDITWLPVRRKAYWEVKFEGI-GLGDEYAELESHGAAIDTGTSLITL 226 Query: 276 QQDVAQDIIDAFQAELKSDGQGHTFYVTDCQTSGTVD---FNFDNNAKISVPASEFTAPL 332 +A+ I A+ GQ Y DC T + FNF N ++ ++T + Sbjct: 227 PSGLAEMINAEIGAKKGWTGQ----YTLDCNTRDNLPDLIFNF-NGYNFTIGPYDYTLEV 281 Query: 333 SYANGQPYPKCQLLLGISDANILGDNFLRSAYLVYDLDDDKISLAQ 378 S + + I+GD FLR Y +YDL ++ + LA+ Sbjct: 282 SGSCISAITPMDFPEPVGPLAIVGDAFLRKYYSIYDLGNNAVGLAK 327 >5BWY-A nrPDB Length = 376 Score = 103 bits (256), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 96/338 (28%), Positives = 152/338 (44%), Gaps = 40/338 (11%) Query: 60 EHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKS 119 +++ + D +G N+Q F I+DTGS++LWVP SV C + C K +Y Sbjct: 59 QNIMFYGDAEVGDNQQPFTFILDTGSANLWVP--SVKC-------TTAGCLTKHLYDSSK 109 Query: 120 STTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKT---------SIP 170 S T + GT + Y G+ S G KD V G S+ + F ++ T S Sbjct: 110 SRTYEKDGTKVEMNYVSGTVS-GFFSKDLVTVGNLSLPYK-FIEVIDTNGFEPTYTASTF 167 Query: 171 QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYS 230 GILG+G+K + + G D + V LKNQ I ++ YL + TG + GG+++ Y Sbjct: 168 DGILGLGWK-DLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGFLTIGGIEERFYE 226 Query: 231 GSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDI---IDAF 287 G L + D +ITL++ VG + + ++DSGT+ + D + +D Sbjct: 227 GPLTYEKLNHDLYWQITLDA--HVGNIMLEKANCIVDSGTSAITVPTDFLNKMLQNLDVI 284 Query: 288 QAELKSDGQGHTFYVTDCQTSGTVDFNF-DNNAKISVPASEFTAPLSYANGQPYPKCQL- 345 + FYVT C S F F N K ++ + L + C L Sbjct: 285 KVPFLP------FYVTLCNNSKLPTFEFTSENGKYTLEPEYY---LQHIEDVGPGLCMLN 335 Query: 346 LLGIS---DANILGDNFLRSAYLVYDLDDDKISLAQVK 380 ++G+ ILGD F+R + V+D D+ + +A K Sbjct: 336 IIGLDFPVPTFILGDPFMRKYFTVFDYDNHSVGIALAK 373 >1XDH-A nrPDB Length = 331 Score = 103 bits (256), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 96/338 (28%), Positives = 152/338 (44%), Gaps = 40/338 (11%) Query: 60 EHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKS 119 +++ + D +G N+Q F I+DTGS++LWVP SV C + C K +Y Sbjct: 14 QNIMFYGDAEVGDNQQPFTFILDTGSANLWVP--SVKC-------TTAGCLTKHLYDSSK 64 Query: 120 STTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKT---------SIP 170 S T + GT + Y G+ S G KD V G S+ + F ++ T S Sbjct: 65 SRTYEKDGTKVEMNYVSGTVS-GFFSKDLVTVGNLSLPYK-FIEVIDTNGFEPTYTASTF 122 Query: 171 QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYS 230 GILG+G+K + + G D + V LKNQ I ++ YL + TG + GG+++ Y Sbjct: 123 DGILGLGWK-DLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGFLTIGGIEERFYE 181 Query: 231 GSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDI---IDAF 287 G L + D +ITL++ VG + + ++DSGT+ + D + +D Sbjct: 182 GPLTYEKLNHDLYWQITLDA--HVGNIMLEKANCIVDSGTSAITVPTDFLNKMLQNLDVI 239 Query: 288 QAELKSDGQGHTFYVTDCQTSGTVDFNF-DNNAKISVPASEFTAPLSYANGQPYPKCQL- 345 + FYVT C S F F N K ++ + L + C L Sbjct: 240 KVPFLP------FYVTLCNNSKLPTFEFTSENGKYTLEPEYY---LQHIEDVGPGLCMLN 290 Query: 346 LLGIS---DANILGDNFLRSAYLVYDLDDDKISLAQVK 380 ++G+ ILGD F+R + V+D D+ + +A K Sbjct: 291 IIGLDFPVPTFILGDPFMRKYFTVFDYDNHSVGIALAK 328 >2BJU-A nrPDB Length = 453 Score = 102 bits (255), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 96/338 (28%), Positives = 152/338 (44%), Gaps = 40/338 (11%) Query: 60 EHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKS 119 +++ + D +G N+Q F I+DTGS++LWVP SV C + C K +Y Sbjct: 136 QNIMFYGDAEVGDNQQPFTFILDTGSANLWVP--SVKC-------TTAGCLTKHLYDSSK 186 Query: 120 STTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKT---------SIP 170 S T + GT + Y G+ S G KD V G S+ + F ++ T S Sbjct: 187 SRTYEKDGTKVEMNYVSGTVS-GFFSKDLVTVGNLSLPYK-FIEVIDTNGFEPTYTASTF 244 Query: 171 QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYS 230 GILG+G+K + + G D + V LKNQ I ++ YL + TG + GG+++ Y Sbjct: 245 DGILGLGWK-DLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGFLTIGGIEERFYE 303 Query: 231 GSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDI---IDAF 287 G L + D +ITL++ VG + + ++DSGT+ + D + +D Sbjct: 304 GPLTYEKLNHDLYWQITLDA--HVGNIMLEKANCIVDSGTSAITVPTDFLNKMLQNLDVI 361 Query: 288 QAELKSDGQGHTFYVTDCQTSGTVDFNF-DNNAKISVPASEFTAPLSYANGQPYPKCQL- 345 + FYVT C S F F N K ++ + L + C L Sbjct: 362 KVPFLP------FYVTLCNNSKLPTFEFTSENGKYTLEPEYY---LQHIEDVGPGLCMLN 412 Query: 346 LLGIS---DANILGDNFLRSAYLVYDLDDDKISLAQVK 380 ++G+ ILGD F+R + V+D D+ + +A K Sbjct: 413 IIGLDFPVPTFILGDPFMRKYFTVFDYDNHSVGIALAK 450 >4AA9-A nrPDB Length = 320 Score = 102 bits (255), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 99/341 (29%), Positives = 159/341 (46%), Gaps = 61/341 (17%) Query: 64 YAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTTS 123 Y I IG+ Q+F V+ DTGSSDLWVP S+ C ++ CK + P+ S+T Sbjct: 13 YFGKIYIGTPPQEFTVVFDTGSSDLWVP--SIYC-------KSNVCKNHHRFDPRKSSTF 63 Query: 124 QNLGTPFYIGYGDGSSSQGTLYKDTVGFGG-------ASITKQVFADITKTSIPQGILGI 176 +NLG P I YG G S +G L DTV ++ + ++ S GILG+ Sbjct: 64 RNLGKPLSIHYGTG-SMEGFLGYDTVTVSNIVDPNQTVGLSTEQPGEVFTYSEFDGILGL 122 Query: 177 GYKTNEAAGDYDNVPV--TLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSGSLI 234 Y + A +Y +VPV + ++ ++A++ +S+Y++ N + G +D + Y+GSL Sbjct: 123 AYPS--LASEY-SVPVFDNMMDRHLVARDLFSVYMDR-NGQGSMLTLGAIDPSYYTGSLH 178 Query: 235 AVPVTSDRELRITLNS--LKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAELK 292 VPVT + + T++S + V G +LD+GT++ + + DI+ A Sbjct: 179 WVPVTLQQYWQFTVDSVTINGVAVACVGGCQAILDTGTSVLF---GPSSDILKIQMAIGA 235 Query: 293 SDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYP--------KCQ 344 ++ + G D N N S+P F NG+ YP K Q Sbjct: 236 TENR-----------YGEFDVNCGNLR--SMPTVVFE-----INGRDYPLSPSAYTSKDQ 277 Query: 345 LLL-------GISDANILGDNFLRSAYLVYDLDDDKISLAQ 378 S+ ILGD F+R Y V+D ++++ LA+ Sbjct: 278 GFCTSGFQGDNNSELWILGDVFIREYYSVFDRANNRVGLAK 318 >1MIQ-A nrPDB Length = 375 Score = 100 bits (248), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 95/333 (28%), Positives = 150/333 (45%), Gaps = 32/333 (9%) Query: 61 HVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSS 120 ++ + + +G N QKF +I DTGS++LWVP S C+ C K +Y S Sbjct: 61 NIMFYGEGEVGDNHQKFMLIFDTGSANLWVP--SKKCNSSG-------CSIKNLYDSSKS 111 Query: 121 TTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIPQ--------- 171 + + GT I YG G + +G KD V G S+ + F ++T T + Sbjct: 112 KSYEKDGTKVDITYGSG-TVKGFFSKDLVTLGHLSMPYK-FIEVTDTDDLEPIYSSVEFD 169 Query: 172 GILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSG 231 GILG+G+K + + G D + V LKNQ I ++ YL + G + GG+++ Y G Sbjct: 170 GILGLGWK-DLSIGSIDPIVVELKNQNKIDNALFTFYLPVHDVHAGYLTIGGIEEKFYEG 228 Query: 232 SLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAEL 291 ++ + D +I L+ GK +V++DSGTT + ++ F A L Sbjct: 229 NITYEKLNHDLYWQIDLDV--HFGKQTMEKANVIVDSGTTTI----TAPSEFLNKFFANL 282 Query: 292 KSDGQGHT-FYVTDC--QTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLG 348 FYVT C + T++F NN P + P+ + L + Sbjct: 283 NVIKVPFLPFYVTTCDNKEMPTLEFKSANNTYTLEPEY-YMNPILEVDDTLCMITMLPVD 341 Query: 349 I-SDANILGDNFLRSAYLVYDLDDDKISLAQVK 380 I S+ ILGD F+R + V+D D + + A K Sbjct: 342 IDSNTFILGDPFMRKYFTVFDYDKESVGFAIAK 374 >2ASI-A nrPDB Length = 361 Score = 99.4 bits (246), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 94/355 (26%), Positives = 151/355 (42%), Gaps = 63/355 (17%) Query: 64 YAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTTS 123 YA ++IG+ Q F ++ DTGSSD WVP T ++ C G + P +S+T Sbjct: 20 YAIPVSIGTPGQDFLLLFDTGSSDTWVPHKGCT--------KSEGCVGSRFFDPSASSTF 71 Query: 124 QNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP------------Q 171 + I YG G ++ G ++D++ G ++TKQ+ A + P Sbjct: 72 KATNYNLNITYGTGGAN-GLYFEDSIAIGDITVTKQILAYVDNVRGPTAEQSPNADIFLD 130 Query: 172 GILGIGYKTN-----EAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDK 226 G+ G Y N E Y+ V V L QG+I+ +S+Y+N+ N+ TG+++FGGV+ Sbjct: 131 GLFGAAYPDNTAMEAEYGSTYNTVHVNLYKQGLISSPLFSVYMNT-NSGTGEVVFGGVNN 189 Query: 227 AKYSGSLIAVPVTSDRELRITLNSLKAVGKNINGNIDV--------LLDSGTTITYLQQD 278 G + V S R G ++G+ V +D+GT + Sbjct: 190 TLLGGDIAYTDVMS-RYGGYYFWDAPVTGITVDGSAAVRFSRPQAFTIDTGTNFFIMPSS 248 Query: 279 VAQDIIDAFQAELKSDGQGHTFYVTDC--------------QTSGTVDFNFDNNAKISVP 324 A I+ A + QG +V C Q SG+ + +ISVP Sbjct: 249 AASKIVKAALPDATETQQG---WVVPCASYQNSKSTISIVMQKSGSS----SDTIEISVP 301 Query: 325 ASEFTAPLSYANGQPYPKCQLLLGISDAN--ILGDNFLRSAYLVYDLDDDKISLA 377 S+ P+ +N C ++ N I+G+ FLR VYD +++I A Sbjct: 302 VSKMLLPVDQSN----ETCMFIILPDGGNQYIVGNLFLRFFVNVYDFGNNRIGFA 352 >2ANL-A nrPDB Length = 327 Score = 99.0 bits (245), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 98/328 (29%), Positives = 147/328 (44%), Gaps = 40/328 (12%) Query: 70 IGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTTSQNLGTP 129 +G N QKF +I DTGS++LWVP S C+ C K +Y S + + GT Sbjct: 22 VGDNHQKFMLIFDTGSANLWVP--SKKCNSIG-------CSTKHLYDSSKSKSYEKDGTK 72 Query: 130 FYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIPQ---------GILGIGYKT 180 I YG G + +G KD V G S+ + F ++T T + GILG+G+K Sbjct: 73 VEITYGSG-TVRGFFSKDLVTLGYLSLPYK-FIEVTDTDDLEPLYTAAEFDGILGLGWK- 129 Query: 181 NEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSGSLIAVPVTS 240 + + G D + V LKNQ I + ++ YL + +G + GG+++ Y G L + Sbjct: 130 DLSIGSIDPIVVELKNQNKIDQALFTFYLPVHDKHSGYLTIGGIEEKFYEGELTYEKLNH 189 Query: 241 DRELRITLNSLKAVGKNINGNIDVLLDSGT-TITYLQQDVAQDIIDAFQAELKSDGQGHT 299 D ++ L+ GK +V++DSGT TIT I+ F +L Sbjct: 190 DLFWQVDLDV--NFGKTSMEKANVIVDSGTSTIT-----APTSFINKFFKDLNVIKVPFL 242 Query: 300 -FYVTDCQTSG--TVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGISDAN--- 353 FY+T C T++F NN P + PL + C L + D + Sbjct: 243 PFYITTCNNKDMPTLEFKSANNTYTLEPEY-YMEPLLDIDDT---LCMLYILPVDIDKNT 298 Query: 354 -ILGDNFLRSAYLVYDLDDDKISLAQVK 380 ILGD F+R + V+D D + I A K Sbjct: 299 FILGDPFMRKYFTVFDYDKESIGFAVAK 326 >1QS8-A nrPDB Length = 329 Score = 98.2 bits (243), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 93/332 (28%), Positives = 146/332 (43%), Gaps = 30/332 (9%) Query: 61 HVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSS 120 ++ + + +G N QKF +I DTGS++LWVP S C+ C K +Y S Sbjct: 15 NIMFYGEGEVGDNHQKFMLIFDTGSANLWVP--SKKCNSSG-------CSIKNLYDSSKS 65 Query: 121 TTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP--------QG 172 + + GT I YG G + +G KD V G S+ + I + G Sbjct: 66 KSYEKDGTKVDITYGSG-TVKGFFSKDLVTLGHLSMPYKFIEVIDTDDLEPIYSSVEFDG 124 Query: 173 ILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSGS 232 ILG+G+K + + G D + V LKNQ I ++ YL + G + GG+++ Y G+ Sbjct: 125 ILGLGWK-DLSIGSIDPIVVELKNQNKIDNALFTFYLPVHDVHAGYLTIGGIEEKFYEGN 183 Query: 233 LIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAELK 292 + + D +I L+ GK +V++DSGTT + ++ F A L Sbjct: 184 ITYEKLNHDLYWQIDLDV--HFGKQTMEKANVIVDSGTTTI----TAPSEFLNKFFANLN 237 Query: 293 SDGQGHT-FYVTDC--QTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGI 349 FYVT C + T++F NN P + P+ + L + I Sbjct: 238 VIKVPFLPFYVTTCDNKEMPTLEFKSANNTYTLEPEY-YMNPILEVDDTLCMITMLPVDI 296 Query: 350 -SDANILGDNFLRSAYLVYDLDDDKISLAQVK 380 S+ ILGD F+R + V+D D + + A K Sbjct: 297 DSNTFILGDPFMRKYFTVFDYDKESVGFAIAK 328 >5JOD-A nrPDB Length = 375 Score = 97.8 bits (242), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 97/328 (29%), Positives = 147/328 (44%), Gaps = 40/328 (12%) Query: 70 IGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTTSQNLGTP 129 IG+NKQ F I DTGS++LWVP SV CD C K +Y +S + + GT Sbjct: 69 IGTNKQPFMFIFDTGSANLWVP--SVNCDSIG-------CSTKHLYDASASKSYEKDGTK 119 Query: 130 FYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKT---------SIPQGILGIGYKT 180 I YG G + +G KD + G S+ + F ++T S GILG+G+K Sbjct: 120 VEISYGSG-TVRGYFSKDVISLGDLSLPYK-FIEVTDADDLEPIYSGSEFDGILGLGWK- 176 Query: 181 NEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSGSLIAVPVTS 240 + + G D V V LK Q I ++ YL + G + GG++ Y G L + Sbjct: 177 DLSIGSIDPVVVELKKQNKIDNALFTFYLPVHDKHVGYLTIGGIESDFYEGPLTYEKLNH 236 Query: 241 DRELRITLNSLKAVGKNINGNIDVLLDSGT-TITYLQQDVAQDIIDAFQAELKSDGQGHT 299 D +I L+ GK + + ++DSGT TIT ++ F ++ Sbjct: 237 DLYWQIDLDI--HFGKYVMQKANAVVDSGTSTIT-----APTSFLNKFFRDMNVIKVPFL 289 Query: 300 -FYVTDCQTSG--TVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGISDAN--- 353 YVT C T++F+ NN K ++ + PLS + C L + D + Sbjct: 290 PLYVTTCDNDDLPTLEFHSRNN-KYTLEPEFYMDPLSDIDPA---LCMLYILPVDIDDNT 345 Query: 354 -ILGDNFLRSAYLVYDLDDDKISLAQVK 380 ILGD F+R + V+D + + + A K Sbjct: 346 FILGDPFMRKYFTVFDYEKESVGFAVAK 373 >5I70-B nrPDB Length = 328 Score = 97.8 bits (242), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 97/328 (29%), Positives = 147/328 (44%), Gaps = 40/328 (12%) Query: 70 IGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTTSQNLGTP 129 IG+NKQ F I DTGS++LWVP SV CD C K +Y +S + + GT Sbjct: 22 IGTNKQPFMFIFDTGSANLWVP--SVNCDSIG-------CSTKHLYDASASKSYEKDGTK 72 Query: 130 FYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKT---------SIPQGILGIGYKT 180 I YG G + +G KD + G S+ + F ++T S GILG+G+K Sbjct: 73 VEISYGSG-TVRGYFSKDVISLGDLSLPYK-FIEVTDADDLEPIYSGSEFDGILGLGWK- 129 Query: 181 NEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSGSLIAVPVTS 240 + + G D V V LK Q I ++ YL + G + GG++ Y G L + Sbjct: 130 DLSIGSIDPVVVELKKQNKIDNALFTFYLPVHDKHVGYLTIGGIESDFYEGPLTYEKLNH 189 Query: 241 DRELRITLNSLKAVGKNINGNIDVLLDSGT-TITYLQQDVAQDIIDAFQAELKSDGQGHT 299 D +I L+ GK + + ++DSGT TIT ++ F ++ Sbjct: 190 DLYWQIDLDI--HFGKYVMQKANAVVDSGTSTIT-----APTSFLNKFFRDMNVIKVPFL 242 Query: 300 -FYVTDCQTSG--TVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGISDAN--- 353 YVT C T++F+ NN K ++ + PLS + C L + D + Sbjct: 243 PLYVTTCDNDDLPTLEFHSRNN-KYTLEPEFYMDPLSDIDPA---LCMLYILPVDIDDNT 298 Query: 354 -ILGDNFLRSAYLVYDLDDDKISLAQVK 380 ILGD F+R + V+D + + + A K Sbjct: 299 FILGDPFMRKYFTVFDYEKESVGFAVAK 326 >5MKT-A nrPDB Length = 389 Score = 96.7 bits (239), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 96/348 (27%), Positives = 163/348 (46%), Gaps = 39/348 (11%) Query: 54 PVTLNNE-HVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGK 112 PV L N + Y +I IG+ Q F VI DTGS++LWVP S C + C Sbjct: 52 PVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVP--STKCSRLYLA-----CGIH 104 Query: 113 GIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTS-IP- 170 +Y S++ G+ F I YG G +G L +D+V GG ++T Q F ++T+ IP Sbjct: 105 SLYESSDSSSYMENGSDFTIHYGSG-RVKGFLSQDSVTVGGITVT-QTFGEVTELPLIPF 162 Query: 171 -----QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNS-PNAATGQIIFGGV 224 G+LG+G+ +A G V + +QGV+ + +S+Y N + G+++ GG Sbjct: 163 MLAKFDGVLGMGFPA-QAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGS 221 Query: 225 DKAKYSGSLIAVPVTSDRELRITLNSLKAVGKN---INGNIDVLLDSGTTITYLQQDVAQ 281 D Y G+ V ++ +IT+ + +VG + V++D+G++ + Sbjct: 222 DPQHYQGNFHYVSISKTDSWQITMKGV-SVGSSTLLCEEGCAVVVDTGSSFISAPTSSLK 280 Query: 282 DIIDAFQAELKSDGQGHTFYVTDCQTSGTV-DFNFDNNAK-ISVPASEFTAPLSYANGQP 339 I+ A A+ K + YV +C T+ D +FD + ++ ++++ L Y N + Sbjct: 281 LIMQALGAKEKRIEE----YVVNCSQVPTLPDISFDLGGRAYTLSSTDYV--LQYPNRRD 334 Query: 340 YPKCQLLLGISD-------ANILGDNFLRSAYLVYDLDDDKISLAQVK 380 C L L D +LG F+R Y +D +++I A + Sbjct: 335 -KLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 381 >5UX4-A nrPDB Length = 420 Score = 96.3 bits (238), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 106/382 (27%), Positives = 166/382 (43%), Gaps = 62/382 (16%) Query: 34 VIKTPVNATGQEG--KVKRQAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVP 91 ++K P+ + + K + N Y +I IG+ Q F V+ DTGSS+LWVP Sbjct: 46 ILKGPITKYSMQSSPRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVP 105 Query: 92 DASVTCDKPRPGQSADF-CKGKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVG 150 S+ C + D C Y S+T GT F I YG GS S G L +DTV Sbjct: 106 --SIHC------KLLDIACWVHHKYNSDKSSTYVKNGTSFDIHYGSGSLS-GYLSQDTVS 156 Query: 151 ------FGGASITKQVFADITK-------TSIPQGILGIGY---KTNEAAGDYDNVPVTL 194 GG + KQ+F + TK + GILG+GY N +DN L Sbjct: 157 VPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGILGMGYPFISVNNVLPVFDN----L 212 Query: 195 KNQGVIAKNAYSLYLNS-PNAAT-GQIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLK 252 Q ++ KN +S YLN P G+++ GG D Y G L + VT ++ ++ L+ Sbjct: 213 MKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLE 272 Query: 253 AVGKNI---NGNIDVLLDSGTTITYLQQDVAQDIIDAFQAELKSDGQGHTFYVTDCQTSG 309 VG + G + ++D+GT++ D +++ A A G+ Y+ C+ Sbjct: 273 -VGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKAIGAVPLIQGE----YMIPCEKVS 327 Query: 310 TVDF--------NFDNNAK---ISVPASEFTAPLSYANGQ--PYPKCQLLLGISDANILG 356 ++ N++ + + + V + T LS G P P L ILG Sbjct: 328 SLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDIPPPSGPLW-------ILG 380 Query: 357 DNFLRSAYLVYDLDDDKISLAQ 378 D F+ Y V+D + +++ A+ Sbjct: 381 DVFIGCYYTVFDREYNRVGFAK 402 >1AVF-A nrPDB Length = 329 Score = 95.9 bits (237), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 96/346 (27%), Positives = 149/346 (43%), Gaps = 63/346 (18%) Query: 63 SYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTT 122 +Y +I+IG+ Q F V+ DTGSS+LWVP SV C + C + P S+T Sbjct: 13 AYFGEISIGTPPQNFLVLFDTGSSNLWVP--SVYCQ-------SQACTSHSRFNPSESST 63 Query: 123 SQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFA-----DITKTSIPQ--GILG 175 G F + YG GS + G DT+ + Q F T Q GI+G Sbjct: 64 YSTNGQTFSLQYGSGSLT-GFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMG 122 Query: 176 IGYKTNEAAGDYDNVPVTLK---NQGVIAKNAYSLYL-NSPNAATGQIIFGGVDKAKYSG 231 + Y A D ++ +G + +S+YL N ++ G ++FGGVD + Y+G Sbjct: 123 LAYP----ALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGVDSSLYTG 178 Query: 232 SLIAVPVTSDRELRITLNSL----KAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAF 287 + PVT + +I + +A G G ++D+GT++ + Q ++ A Sbjct: 179 QIYWAPVTQELYWQIGIEEFLIGGQASGWCSEG-CQAIVDTGTSLLTVPQQYMSALLQAT 237 Query: 288 QAELKSDGQGHTFYVTDC---QTSGTVDFNFDNNAKISVPASEFTAP------------- 331 A+ GQ ++ +C Q ++ F N + +P S + Sbjct: 238 GAQEDEYGQ----FLVNCNSIQNLPSLTF-IINGVEFPLPPSSYILSNNGYCTVGVEPTY 292 Query: 332 LSYANGQPYPKCQLLLGISDANILGDNFLRSAYLVYDLDDDKISLA 377 LS NGQP ILGD FLRS Y VYDL ++++ A Sbjct: 293 LSSQNGQP------------LWILGDVFLRSYYSVYDLGNNRVGFA 326 >5N71-A nrPDB Length = 345 Score = 95.5 bits (236), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 94/346 (27%), Positives = 160/346 (46%), Gaps = 51/346 (14%) Query: 62 VSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSST 121 V Y I+IG+ Q F VI DTGS++LW+P + T +C Y S+ Sbjct: 16 VVYYGPISIGTPPQDFQVIFDTGSANLWLPSSKCT---------TKYCLHHHRYDSSKSS 66 Query: 122 TSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFAD---ITKTSIPQ----GIL 174 T + G F I YG G + +G + KD G A ++ Q + + S+ + GIL Sbjct: 67 TYEADGRNFTIVYGSG-NVEGFISKDVCRIGSAKVSGQPLGEALVVGGESLLEAPFDGIL 125 Query: 175 GIGYKTNEAAGDYDNVPV--TLKNQGVIA-KNAYSLYLNSPNAAT--GQIIFGGVDKAKY 229 G+ Y + G VPV + QG++ +N +S+YLN ++ G+++FGG+D Y Sbjct: 126 GLAYPSIAVDG---VVPVFDNMMKQGLLGEQNVFSVYLNRDPSSKEGGEVLFGGIDHDHY 182 Query: 230 SGSLIAVPVTSDRELRITLNSLKAVGKN-------INGNIDVLLDSGTT-ITYLQQDVAQ 281 GS+ VPVT+ + ++ +K+V + + + ++GT+ IT ++V Sbjct: 183 KGSITYVPVTAKGYWQFHVDGVKSVSASKSAPELLCKDGCEAIANTGTSLITGPPEEV-- 240 Query: 282 DIIDAFQAELKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAP----LSYANG 337 D ++ + K++G Y+ DC ++ N ++ EF+ + N Sbjct: 241 DSLNQYLGGTKTEGGQ---YLLDCDKLESLP-----NVTFTISGKEFSLRSKDYVLKVNQ 292 Query: 338 QPYPKC-QLLLGISDAN---ILGDNFLRSAYLVYDLDDDKISLAQV 379 Q C +G+ ILGD FL Y ++D D D++ A+V Sbjct: 293 QGQTLCVSGFMGLEMPQPLWILGDVFLGPYYTIFDRDQDRVGFAEV 338 >1SMR-A nrPDB Length = 335 Score = 95.1 bits (235), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 94/347 (27%), Positives = 162/347 (46%), Gaps = 37/347 (10%) Query: 54 PVTLNNE-HVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGK 112 PV L N + Y +I IG+ Q F VI DTGS++LWVP S C + C Sbjct: 6 PVVLTNYLNSQYYGEIGIGTPPQTFKVIFDTGSANLWVP--STKCSRLYLA-----CGIH 58 Query: 113 GIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTS-IP- 170 +Y S++ G F I YG G +G L +D+V GG ++T Q F ++T+ IP Sbjct: 59 SLYESSDSSSYMENGDDFTIHYGSG-RVKGFLSQDSVTVGGITVT-QTFGEVTQLPLIPF 116 Query: 171 -----QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNS-PNAATGQIIFGGV 224 G+LG+G+ +A G V + +QGV+ + +S+Y N P+ G+++ GG Sbjct: 117 MLAQFDGVLGMGFPA-QAVGGVTPVFDHILSQGVLKEKVFSVYYNRGPHLLGGEVVLGGS 175 Query: 225 DKAKYSGSLIAVPVTSDRELRITLNSLKAVGKN---INGNIDVLLDSGTTITYLQQDVAQ 281 D Y G V ++ +IT+ + +VG + +V++D+G++ + Sbjct: 176 DPQHYQGDFHYVSLSKTDSWQITMKGV-SVGSSTLLCEEGCEVVVDTGSSFISAPTSSLK 234 Query: 282 DIIDAFQAELKSDGQGHTFYVTDCQTSGTVDFNFDNNAK-ISVPASEFTAPLSYANGQPY 340 I+ A A+ K + H + V+ Q D +F+ + ++ ++++ L Y N + Sbjct: 235 LIMQALGAKEK---RLHEYVVSCSQVPTLPDISFNLGGRAYTLSSTDYV--LQYPNRRD- 288 Query: 341 PKCQLLLGISD-------ANILGDNFLRSAYLVYDLDDDKISLAQVK 380 C + L D +LG F+R Y +D +++I A + Sbjct: 289 KLCTVALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 335 >3QS1-A nrPDB Length = 336 Score = 91.3 bits (225), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 99/351 (28%), Positives = 146/351 (41%), Gaps = 55/351 (15%) Query: 55 VTLNN-EHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKG 113 VTLN+ +V Y + IG NKQKF I DTGS++LWVP A C+ CK K Sbjct: 13 VTLNDVANVMYYGEAQIGDNKQKFAFIFDTGSANLWVPSAQ--CNTIG-------CKTKN 63 Query: 114 IYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIPQ-- 171 +Y S T + GT + Y G+ S G KD V S + F ++T T+ + Sbjct: 64 LYDSNKSKTYEKDGTKVEMNYVSGTVS-GFFSKDIVTIANLSFPYK-FIEVTDTNGFEPA 121 Query: 172 -------GILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGV 224 GI+G+G+K + + G D V V LKNQ I + ++ YL + G + GG+ Sbjct: 122 YTLGQFDGIVGLGWK-DLSIGSVDPVVVELKNQNKIEQAVFTFYLPFDDKHKGYLTIGGI 180 Query: 225 DKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDII 284 + Y G L + D ++ L+ G ++DSGT+ + Sbjct: 181 EDRFYEGQLTYEKLNHDLYWQVDLDL--HFGNLTVEKATAIVDSGTSSITAPTEFLNKFF 238 Query: 285 DAFQAELKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQ 344 + Y+T C NN K+ P EF + + +P Q Sbjct: 239 EGLDV---VKIPFLPLYITTC-----------NNPKL--PTLEFRSATNVYTLEPEYYLQ 282 Query: 345 LL--LGIS---------DAN----ILGDNFLRSAYLVYDLDDDKISLAQVK 380 + GIS D N ILGD F+R + V+D D+ + A K Sbjct: 283 QIFDFGISLCMVSIIPVDLNKNTFILGDPFMRKYFTVFDYDNHTVGFALAK 333 >1MPP-A nrPDB Length = 361 Score = 87.8 bits (216), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 94/354 (26%), Positives = 151/354 (42%), Gaps = 61/354 (17%) Query: 64 YAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTTS 123 YA ++IG+ Q F ++ DTGSSD WVP CD +++ C GK + P SS+T Sbjct: 20 YAIPVSIGTPGQDFYLLFDTGSSDTWVPHKG--CD------NSEGCVGKRFFDPSSSSTF 71 Query: 124 QNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP------------Q 171 + I YG G ++ G ++D++ GGA++ +Q A + S P Sbjct: 72 KETDYNLNITYGTGGAN-GIYFRDSITVGGATVKQQTLAYVDNVSGPTAEQSPDSELFLD 130 Query: 172 GILGIGYKTNEAA----GD-YDNVPVTLKNQGVIAKNAYSLYLNSPNAAT---------- 216 GI G Y N A GD Y+ V V L QG+I+ +S+Y+N+ + Sbjct: 131 GIFGAAYPDNTAMEAEYGDTYNTVHVNLYKQGLISSPVFSVYMNTNDGGGQVVFGGVNNT 190 Query: 217 ---GQIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTIT 273 G I + V K++ PVT + ++ AV + +G +D+GT Sbjct: 191 LLGGDIQYTDVLKSRGGYFFWDAPVTG-----VKIDGSDAV--SFDGAQAFTIDTGTNFF 243 Query: 274 YLQQDVAQDIIDAFQAELKSDGQGHTFYVTDCQTSGTVDFNF--------DNNAKISVPA 325 A+ ++ A + QG+T + Q S T F+ + +SVP Sbjct: 244 IAPSSFAEKVVKAALPDATESQQGYTVPCSKYQDSKTT-FSLVLQKSGSSSDTIDVSVPI 302 Query: 326 SEFTAPLSYANGQPYPKCQLLLGISDAN--ILGDNFLRSAYLVYDLDDDKISLA 377 S+ P+ + C ++ N I+G+ FLR VYD ++I A Sbjct: 303 SKMLLPVDKSG----ETCMFIVLPDGGNQFIVGNLFLRFFVNVYDFGKNRIGFA 352 >3FNT-A nrPDB Length = 332 Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 83/327 (25%), Positives = 138/327 (42%), Gaps = 38/327 (11%) Query: 70 IGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTTSQNLGTP 129 +G N QKFN + T SS++WVP S+ C +++ C+ K Y S T + TP Sbjct: 26 LGDNGQKFNFLFHTASSNVWVP--SIKC-------TSESCESKNHYDSSKSKTYEKDDTP 76 Query: 130 FYIGYGDGSSSQGTLYKDTVGFGGASITKQV--------FADITKTSIPQGILGIGYKTN 181 + G+ S G KD V G S+ + F S G+ G+G+K + Sbjct: 77 VKLTSKAGTIS-GIFSKDLVTIGKLSVPYKFIEMTEIVGFEPFYSESDVDGVFGLGWK-D 134 Query: 182 EAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSGSLIAVPVTSD 241 + G D V LK Q I + YS+YL N G + GG+++ + G L + D Sbjct: 135 LSIGSIDPYIVELKTQNKIEQAVYSIYLPPENKNKGYLTIGGIEERFFDGPLNYEKLNHD 194 Query: 242 RELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDA---FQAELKSDGQGH 298 ++ L+ G + +V+LDS T++ + + +++ F+ S Sbjct: 195 LMWQVDLDV--HFGNVSSKKANVILDSATSVITVPTEFFNQFVESASVFKVPFLS----- 247 Query: 299 TFYVTDCQTSGTVDFNFDNNAKI-SVPASEFTAPLSYANGQPYPKCQLLLGISDAN---- 353 YVT C + + + K+ ++ ++ PL C L + D Sbjct: 248 -LYVTTCGNTKLPTLEYRSPNKVYTLEPKQYLEPLENIFSA---LCMLNIVPIDLEKNTF 303 Query: 354 ILGDNFLRSAYLVYDLDDDKISLAQVK 380 +LGD F+R + VYD D+ + A K Sbjct: 304 VLGDPFMRKYFTVYDYDNHTVGFALAK 330 >1B5F-A nrPDB Length = 239 Score = 85.5 bits (210), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 64/199 (32%), Positives = 96/199 (48%), Gaps = 27/199 (13%) Query: 52 AIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKG 111 A+ N+ SY +I IG+ QKF VI DTGSS LWVP + K C+ Sbjct: 3 AVVALTNDRDTSYFGEIGIGTPPQKFTVIFDTGSSVLWVPSSKCINSKA--------CRA 54 Query: 112 KGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTS--- 168 +Y S+T + GT I YG GS + G +D+V G + +Q F + T + Sbjct: 55 HSMYESSDSSTYKENGTFGAIIYGTGSIT-GFFSQDSVTIGDLVVKEQDFIEATDEADNV 113 Query: 169 ----IPQGILGIGYKTNEAAGDYDNVPV--TLKNQGVIAKNAYSLYLNS--PNAATGQII 220 + GILG+ ++T +VPV + NQG++ + +S +LN G+++ Sbjct: 114 FLHRLFDGILGLSFQT-------ISVPVWYNMLNQGLVKERRFSFWLNRNVDEEEGGELV 166 Query: 221 FGGVDKAKYSGSLIAVPVT 239 FGG+D + G VPVT Sbjct: 167 FGGLDPNHFRGDHTYVPVT 185 >5MLG-A nrPDB Length = 389 Score = 84.7 bits (208), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 94/352 (26%), Positives = 151/352 (42%), Gaps = 47/352 (13%) Query: 54 PVTLNNE-HVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGK 112 PV L N Y +I IG+ Q F VI DTGS++LWVP S C G C+ Sbjct: 52 PVVLTNYLDTQYYGEIGIGTPSQTFKVIFDTGSANLWVP--STKC-----GPLYTACEIH 104 Query: 113 GIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTS-IP- 170 +Y S++ GT F I YG G +G L +D V GG +T Q F ++T+ IP Sbjct: 105 NLYDSSESSSYMENGTEFTIHYGSG-KVKGFLSQDVVTVGGIIVT-QTFGEVTELPLIPF 162 Query: 171 -----QGILGIGYKTNEAAGDYDNVPV--TLKNQGVIAKNAYSLYLNSPNAAT-GQIIFG 222 G+LG+G+ G +PV + +Q V+ + +S+Y + + G+++ G Sbjct: 163 MLAKFDGVLGMGFPAQAVDG---VIPVFDHILSQRVLKEEVFSVYYSRESHLLGGEVVLG 219 Query: 223 GVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKN---INGNIDVLLDSGTTITYLQQDV 279 G D Y G+ V ++ +IT+ + +VG ++D+GT+ Sbjct: 220 GSDPQHYQGNFHYVSISKAGSWQITMKGV-SVGPATLLCEEGCMAVVDTGTSYISGPTSS 278 Query: 280 AQDIIDAFQAELKSDGQGHTFYVTDCQTSGTV-DFNFDNNAKISVPASEFTAPLSYANGQ 338 Q I+ A + K YV +C T+ D +F + ++ + Y Sbjct: 279 LQLIMQALGVKEKRANN----YVVNCSQVPTLPDISFYLGGRTYTLSN-----MDYVQKN 329 Query: 339 PYPK---CQLLLGISD-------ANILGDNFLRSAYLVYDLDDDKISLAQVK 380 P+ C L L D +LG F+R Y +D +++I A + Sbjct: 330 PFRNDDLCILALQGLDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 381 >3QVI-A nrPDB Length = 451 Score = 84.7 bits (208), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 84/328 (25%), Positives = 142/328 (43%), Gaps = 40/328 (12%) Query: 70 IGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTTSQNLGTP 129 +G N QKFN + T SS++WVP S+ C +++ C+ K Y S T + TP Sbjct: 145 LGDNGQKFNFLFHTASSNVWVP--SIKC-------TSESCESKNHYDSSKSKTYEKDDTP 195 Query: 130 FYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITK---------TSIPQGILGIGYKT 180 + G+ S G KD V G S+ + F ++T+ S G+ G+G+K Sbjct: 196 VKLTSKAGTIS-GIFSKDLVTIGKLSVPYK-FIEMTEIVGFEPFYSESDVDGVFGLGWK- 252 Query: 181 NEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSGSLIAVPVTS 240 + + G D V LK Q I + YS+YL N G + GG+++ + G L + Sbjct: 253 DLSIGSIDPYIVELKTQNKIEQAVYSIYLPPENKNKGYLTIGGIEERFFDGPLNYEKLNH 312 Query: 241 DRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDA---FQAELKSDGQG 297 D ++ L+ G + +V+LDS T++ + + +++ F+ S Sbjct: 313 DLMWQVDLDV--HFGNVSSKKANVILDSATSVITVPTEFFNQFVESASVFKVPFLS---- 366 Query: 298 HTFYVTDCQTSGTVDFNFDNNAKI-SVPASEFTAPLSYANGQPYPKCQLLLGISDAN--- 353 YVT C + + + K+ ++ ++ PL C L + D Sbjct: 367 --LYVTTCGNTKLPTLEYRSPNKVYTLEPKQYLEPLENIFSAL---CMLNIVPIDLEKNT 421 Query: 354 -ILGDNFLRSAYLVYDLDDDKISLAQVK 380 +LGD F+R + VYD D+ + A K Sbjct: 422 FVLGDPFMRKYFTVYDYDNHTVGFALAK 449 >5NFG-A nrPDB Length = 383 Score = 81.6 bits (200), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 71/227 (31%), Positives = 104/227 (45%), Gaps = 22/227 (9%) Query: 58 NNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTP 117 N+ +Y +I IG+ Q F VI DTGSSDLWVP S CD C Y Sbjct: 56 NDRDTAYYGEIGIGTPPQNFAVIFDTGSSDLWVP--STKCDTSLA------CVIHPRYDS 107 Query: 118 KSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKT-------SIP 170 S+T + GT I YG G+ G +D+V G + Q F + T+ S Sbjct: 108 GDSSTYKGNGTTASIQYGTGAIV-GFYSQDSVEVGDLVVEHQDFIETTEEDDTVFLKSEF 166 Query: 171 QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNS--PNAATGQIIFGGVDKAK 228 GILG+G++ +AG V + NQG++ + +S +LN G+++FGGVD Sbjct: 167 DGILGLGFQ-EISAGKAVPVWYNMVNQGLVEEAVFSFWLNRNVDEEEGGELVFGGVDPNH 225 Query: 229 YSGSLIAVPVTSDRELRITLNSLKAVGKN---INGNIDVLLDSGTTI 272 + G+ VPVT + + + K+ G + DSGT+ Sbjct: 226 FRGNHTYVPVTRKGYWQFEMGDVLIGDKSSGFCAGGCAAIADSGTSF 272 >5HCT-A nrPDB Length = 419 Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 98/327 (29%), Positives = 153/327 (46%), Gaps = 45/327 (13%) Query: 63 SYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTT 122 +Y + IG+ Q N+ DTGSSDLWV + T + G+ IYTP STT Sbjct: 105 AYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASE---------VDGQTIYTPSKSTT 155 Query: 123 SQNL-GTPFYIGYGDGSSSQGTLYKDTVGFGGASIT-------KQVFADITKTSIPQGIL 174 ++ L G + I YGDGSSS G +Y DTV GG ++T K+V + T+ S G+L Sbjct: 156 AKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTGQAVESAKKVSSSFTEDSTIDGLL 215 Query: 175 GIGYKT------NEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAK 228 G+ + T + +DN +L + A Y A G FG +D Sbjct: 216 GLAFSTLNTVSPTQQKTFFDNAKASLDSPVFTADLGYH--------APGTYNFGFIDTTA 267 Query: 229 YSGSLIAVPVTSDRELRITLNSLKAVGKNI--NGNIDVLLDSGTTITYLQQDVAQDIIDA 286 Y+GS+ V++ + ++ AVG + +ID + D+GTT+ YL V + A Sbjct: 268 YTGSITYTAVSTKQGFWEWTSTGYAVGSGTFKSTSIDGIADTGTTLLYLPATV----VSA 323 Query: 287 FQAELKSDGQGHTF--YVTDCQTSGTVDFNFD-NNAKISVPAS--EFTAPLSYANGQPYP 341 + A++ + YV C + F F +A+I +P +F P+S + + Sbjct: 324 YWAQVSGAKSSSSVGGYVFPCSAT-LPSFTFGVGSARIVIPGDYIDF-GPISTGSSSCFG 381 Query: 342 KCQLLLGISDANILGDNFLRSAYLVYD 368 Q GI NI GD L++A++V++ Sbjct: 382 GIQSSAGIG-INIFGDVALKAAFVVFN 407 >3PI0-A nrPDB Length = 330 Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 100/328 (30%), Positives = 155/328 (47%), Gaps = 47/328 (14%) Query: 63 SYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTT 122 +Y + IG+ Q N+ DTGSSDLWV + T + G+ IYTP STT Sbjct: 16 AYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASE---------VDGQTIYTPSKSTT 66 Query: 123 SQNL-GTPFYIGYGDGSSSQGTLYKDTVGFGGASIT-------KQVFADITKTSIPQGIL 174 ++ L G + I YGDGSSS G +Y DTV GG ++T K+V + T+ S G+L Sbjct: 67 AKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTGQAVESAKKVSSSFTEDSTIDGLL 126 Query: 175 GIGYKT------NEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAK 228 G+ + T + +DN +L + A Y A G FG +D Sbjct: 127 GLAFSTLNTVSPTQQKTFFDNAKASLDSPVFTADLGYH--------APGTYNFGFIDTTA 178 Query: 229 YSGSLIAVPVTSDRELRITLNSLKAVGKNI--NGNIDVLLDSGTTITYLQQDVAQDIIDA 286 Y+GS+ V++ + ++ AVG + +ID + D+GTT+ YL V + A Sbjct: 179 YTGSITYTAVSTKQGFWEWTSTGYAVGSGTFKSTSIDGIADTGTTLLYLPATV----VSA 234 Query: 287 FQAELKSDGQGHTF--YVTDCQTSGTV-DFNFD-NNAKISVPAS--EFTAPLSYANGQPY 340 + A++ + YV C S T+ F F +A+I +P +F P+S + + Sbjct: 235 YWAQVSGAKSSSSVGGYVFPC--SATLPSFTFGVGSARIVIPGDYIDF-GPISTGSSSCF 291 Query: 341 PKCQLLLGISDANILGDNFLRSAYLVYD 368 Q GI NI GD L++A++V++ Sbjct: 292 GGIQSSAGIG-INIFGDVALKAAFVVFN 318 >3VCM-A nrPDB Length = 335 Score = 79.0 bits (193), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 83/343 (24%), Positives = 157/343 (45%), Gaps = 41/343 (11%) Query: 58 NNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTP 117 N Y +I IG+ Q F V+ DTGSS++WVP S C + C ++ Sbjct: 14 NYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVP--SSKCSRLYTA-----CVYHKLFDA 66 Query: 118 KSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKT-SIP------ 170 S++ ++ GT + Y G+ S G L +D + GG ++T Q+F ++T+ ++P Sbjct: 67 SDSSSYKHNGTELTLRYSTGTVS-GFLSQDIITVGGITVT-QMFGEVTEMPALPFMLAEF 124 Query: 171 QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYS 230 G++G+G+ +A G + + +QGV+ ++ +S Y N ++ GQI+ GG D Y Sbjct: 125 DGVVGMGF-IEQAIGRVTPIFDNIISQGVLKEDVFSFYYNR-DSLGGQIVLGGSDPQHYE 182 Query: 231 GSLIAVPVTSDRELRITLNSLKAVGKN---INGNIDVLLDSGTTITYLQQDVAQDIIDAF 287 G+ + + +I + + +VG + L+D+G + + +++A Sbjct: 183 GNFHYINLIKTGVWQIQMKGV-SVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEAL 241 Query: 288 QAELKSDGQGHTF-YVTDCQTSGTV-DFNFDNNAK-ISVPASEFTAPLSYANGQPYPKCQ 344 A+ + F YV C T+ D +F K ++ ++++ SY++ + C Sbjct: 242 GAKKR------LFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKK---LCT 292 Query: 345 LLLGISD-------ANILGDNFLRSAYLVYDLDDDKISLAQVK 380 L + D LG F+R Y +D +++I A + Sbjct: 293 LAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR 335 >4AMT-A nrPDB Length = 383 Score = 78.6 bits (192), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 85/347 (24%), Positives = 159/347 (45%), Gaps = 44/347 (12%) Query: 58 NNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTP 117 N Y +I IG+ Q F V+ DTGSS++WVP S C + C ++ Sbjct: 57 NYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVP--SSKCSRLYTA-----CVYHKLFDA 109 Query: 118 KSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKT-SIP------ 170 S++ ++ GT + Y G+ S G L +D + GG ++T Q+F ++T+ ++P Sbjct: 110 SDSSSYKHNGTELTLRYSTGTVS-GFLSQDIITVGGITVT-QMFGEVTEMPALPFMLAEF 167 Query: 171 QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLN--SPNAAT--GQIIFGGVDK 226 G++G+G+ +A G + + +QGV+ ++ +S Y N S N+ + GQI+ GG D Sbjct: 168 DGVVGMGF-IEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDP 226 Query: 227 AKYSGSLIAVPVTSDRELRITLNSLKAVGKN---INGNIDVLLDSGTTITYLQQDVAQDI 283 Y G+ + + +I + + +VG + L+D+G + + + Sbjct: 227 QHYEGNFHYINLIKTGVWQIQMKGV-SVGSSTLLCEDGCLALVDTGASYISGSTSSIEKL 285 Query: 284 IDAFQAELKSDGQGHTF-YVTDCQTSGTV-DFNFDNNAK-ISVPASEFTAPLSYANGQPY 340 ++A A+ + F YV C T+ D +F K ++ ++++ SY++ + Sbjct: 286 MEALGAKKR------LFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKK-- 337 Query: 341 PKCQLLLGISD-------ANILGDNFLRSAYLVYDLDDDKISLAQVK 380 C L + D LG F+R Y +D +++I A + Sbjct: 338 -LCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR 383 >1PPK-E nrPDB Length = 323 Score = 75.9 bits (185), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 93/338 (27%), Positives = 144/338 (42%), Gaps = 44/338 (13%) Query: 56 TLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIY 115 T N+E Y +TIG N+ DTGS+DLWV + + P QS G +Y Sbjct: 11 TANDEE--YITPVTIGGTT--LNLNFDTGSADLWV----FSTELPASQQS-----GHSVY 57 Query: 116 TPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGAS-------ITKQVFADITKTS 168 P S+T + G + I YGDGSS+ G ++ D+V GG + +Q+ A + + Sbjct: 58 NP-SATGKELSGYTWSISYGDGSSASGNVFTDSVTVGGVTAHGQAVQAAQQISAQFQQDT 116 Query: 169 IPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAK 228 G+LG+ + + + +A+ +++ L + G FG +D +K Sbjct: 117 NNDGLLGLAFSSINTVQPQSQTTFFDTVKSSLAQPLFAVALK--HQQPGVYDFGFIDSSK 174 Query: 229 YSGSLIAVPVTSDREL-RITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAF 287 Y+GSL V + + ++S A ++ +G + D+GTT+ L V Sbjct: 175 YTGSLTYTGVDNSQGFWSFNVDSYTAGSQSGDG-FSGIADTGTTLLLLDDSVVSQYYSQV 233 Query: 288 QAELKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTA--PLSYANGQPYPKCQL 345 + G YV DC T N SV S +TA P S N P Sbjct: 234 SGAQQDSNAGG--YVFDCST---------NLPDFSVSISGYTATVPGSLINYGPSGDGST 282 Query: 346 LLGISDAN------ILGDNFLRSAYLVYDLDDDKISLA 377 LG +N I GD FL+S Y+V+D D ++ A Sbjct: 283 CLGGIQSNSGIGFSIFGDIFLKSQYVVFDSDGPQLGFA 320 >1IBQ-A nrPDB Length = 325 Score = 74.3 bits (181), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 99/347 (28%), Positives = 148/347 (42%), Gaps = 44/347 (12%) Query: 49 KRQAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADF 108 K A+ NN+ Y +T+G K ++ DTGS+DLWV + + P Q+ Sbjct: 2 KGSAVTTPQNNDE-EYLTPVTVG--KSTLHLDFDTGSADLWV----FSDELPSSEQT--- 51 Query: 109 CKGKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTS 168 G +YTP SS T + G + I YGDGSS+ G +Y+DTV GG + KQ +K S Sbjct: 52 --GHDLYTPSSSATKLS-GYSWDISYGDGSSASGDVYRDTVTVGGVTTNKQAVEAASKIS 108 Query: 169 IP-------QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSP-------NA 214 G+LG+ + + V K Q S L+SP + Sbjct: 109 SEFVQDTANDGLLGLAFSSINT--------VQPKAQTTFFDTVKSQ-LDSPLFAVQLKHD 159 Query: 215 ATGQIIFGGVDKAKYSGSLIAVPVTSDRELR--ITLNSLKAVGKNINGNIDVLLDSGTTI 272 A G FG +D +KY+GS+ S + T G + + + D+GTT+ Sbjct: 160 APGVYDFGYIDDSKYTGSITYTDADSSQGYWGFSTDGYSIGDGSSSSSGFSAIADTGTTL 219 Query: 273 TYLQQDVAQDIIDAFQAELKSDGQGHTFYVTDCQTSGTVDFNFD-NNAKISVPASEFT-A 330 L ++ + +S G YV C T DF + K VP A Sbjct: 220 ILLDDEIVSAYYEQVSGAQESYEAGG--YVFSCSTD-LPDFTVVIGDYKAVVPGKYINYA 276 Query: 331 PLSYANGQPYPKCQLLLGISDANILGDNFLRSAYLVYDLDDDKISLA 377 P+S + Y Q G+ +ILGD FL+S Y+V++ + K+ A Sbjct: 277 PVSTGSSTCYGGIQSNSGLG-LSILGDVFLKSQYVVFNSEGPKLGFA 322 >1IZE-A nrPDB Length = 323 Score = 71.6 bits (174), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 95/342 (27%), Positives = 148/342 (43%), Gaps = 52/342 (15%) Query: 56 TLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIY 115 T N+E Y +T+G + + DTGS+DLWV + P +S G Y Sbjct: 11 TSNDEE--YITQVTVGDDTLGLDF--DTGSADLWV----FSSQTPSSERS-----GHDYY 57 Query: 116 TPKSSTTSQNL-GTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQ-------VFADITKT 167 TP SS +Q + G + I YGDGSS+ G +YKD V GG S Q V ++ T+ Sbjct: 58 TPGSS--AQKIDGATWSISYGDGSSASGDVYKDKVTVGGVSYDSQAVESAEKVSSEFTQD 115 Query: 168 SIPQGILGIGYKTNEAAGD------YDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIF 221 + G+LG+ + + +DNV +L A +L N+P G F Sbjct: 116 TANDGLLGLAFSSINTVQPTPQKTFFDNVKSSLSE----PIFAVALKHNAP----GVYDF 167 Query: 222 GGVDKAKYSGSLIAVPVTSDRELR-ITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVA 280 G D +KY+GS+ V + + T + + + +I + D+GTT+ L Sbjct: 168 GYTDSSKYTGSITYTDVDNSQGFWGFTADGYSIGSDSSSDSITGIADTGTTLLLLD---- 223 Query: 281 QDIIDAFQ-----AELKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYA 335 I+DA+ A S G+ F ++ DF+ + E+ + Sbjct: 224 DSIVDAYYEQVNGASYDSSQGGYVF----PSSASLPDFSVTIGDYTATVPGEYISFADVG 279 Query: 336 NGQPYPKCQLLLGISDANILGDNFLRSAYLVYDLDDDKISLA 377 NGQ + Q GI +I GD FL+S Y+V+D ++ A Sbjct: 280 NGQTFGGIQSNSGIG-FSIFGDVFLKSQYVVFDASGPRLGFA 320 >1QDM-A nrPDB Length = 478 Score = 71.2 bits (173), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 73/229 (31%), Positives = 104/229 (45%), Gaps = 26/229 (11%) Query: 58 NNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTP 117 N + Y +I +G+ QKF VI DTGSS+LWVP A + C Y Sbjct: 48 NYMNAQYFGEIGVGTPPQKFTVIFDTGSSNLWVPSAKC--------YFSIACYLHSRYKA 99 Query: 118 KSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITK-------TSIP 170 +S+T + G P I YG GS + G +D+V G + Q F + TK + Sbjct: 100 GASSTYKKNGKPAAIQYGTGSIA-GYFSEDSVTVGDLVVKDQEFIEATKEPGITFLVAKF 158 Query: 171 QGILGIGYKTNEAAGDYDNVPVTLK--NQGVIAKNAYSLYLNSP--NAATGQIIFGGVDK 226 GILG+G+K VPV K QG+++ +S +LN G+IIFGG+D Sbjct: 159 DGILGLGFKEISVG---KAVPVWYKMIEQGLVSDPVFSFWLNRHVDEGEGGEIIFGGMDP 215 Query: 227 AKYSGSLIAVPVTSDRELRITLNSLKAVGKNIN---GNIDVLLDSGTTI 272 Y G VPVT + + + GK+ G + DSGT++ Sbjct: 216 KHYVGEHTYVPVTQKGYWQFDMGDVLVGGKSTGFCAGGCAAIADSGTSL 264 >3EMY-A nrPDB Length = 329 Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 94/330 (28%), Positives = 149/330 (45%), Gaps = 33/330 (10%) Query: 64 YAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTP-KSSTT 122 Y ++IG+ Q + DTGSSDLWV + + P+ G IYTP KSST+ Sbjct: 17 YITSVSIGTPAQVLPLDFDTGSSDLWV----FSSETPKSS-----ATGHAIYTPSKSSTS 67 Query: 123 SQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTS-------IPQGILG 175 + G + I YGDGSSS G +Y D V GG S+ Q T+ S + G++G Sbjct: 68 KKVSGASWSISYGDGSSSSGDVYTDKVTIGGFSVNTQGVESATRVSTEFVQDTVISGLVG 127 Query: 176 IGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSGSLIA 235 + + + + +A+ ++ L + G FG +D + G + Sbjct: 128 LAFDSGNQVRPHPQKTWFSNAASSLAEPLFTADLR--HGQNGSYNFGYIDTSVAKGPVAY 185 Query: 236 VPVTSDREL-RITLNSLKAVGKNINGN-IDVLLDSGTTITYLQQDVAQDIIDAFQAELKS 293 PV + + T + G +N N ID + D+GTT+ L +V +DA+ A ++S Sbjct: 186 TPVDNSQGFWEFTASGYSVGGGKLNRNSIDGIADTGTTLLLLDDNV----VDAYYANVQS 241 Query: 294 ---DGQGHTFYVTDCQTSGTVDFNFD-NNAKISVPASEFT-APLSYANGQPYPKCQLLLG 348 D Q V DC F+F ++ I++P PL + + Q G Sbjct: 242 AQYDNQ-QEGVVFDCDED-LPSFSFGVGSSTITIPGDLLNLTPLEEGSSTCFGGLQSSSG 299 Query: 349 ISDANILGDNFLRSAYLVYDLDDDKISLAQ 378 I NI GD L++A +V+DL ++++ AQ Sbjct: 300 IG-INIFGDVALKAALVVFDLGNERLGWAQ 328 >1WKR-A nrPDB Length = 340 Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 93/358 (25%), Positives = 146/358 (40%), Gaps = 65/358 (18%) Query: 52 AIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKG 111 ++P T N+ V Y ++ +GS ++++VDTGSS+ W+ G + K Sbjct: 4 SVPAT--NQLVDYVVNVGVGSPATTYSLLVDTGSSNTWL------------GADKSYVK- 48 Query: 112 KGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIPQ 171 T SS TS + + YG GS S GT Y DTV G +I KQ ++ S Sbjct: 49 ----TSTSSATSDKVS----VTYGSGSFS-GTEYTDTVTLGSLTIPKQSIGVASRDSGFD 99 Query: 172 GILGI----------GYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLN---SPNAATGQ 218 G+ GI G + + V L +QG I N ++ S ++ G+ Sbjct: 100 GVDGILGVGPVDLTVGTLSPHTSTSIPTVTDNLFSQGTIPTNLLAVSFEPTTSESSTNGE 159 Query: 219 IIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAV----GKNINGNIDVLLDSGTTITY 274 + FG D +KY+GS+ P+TS +++ +I + ++D+GTT+T Sbjct: 160 LTFGATDSSKYTGSITYTPITSTSPASAYWGINQSIRYGSSTSILSSTAGIVDTGTTLTL 219 Query: 275 LQQDVAQDIIDAFQAELKSDGQGHTFYVTDCQ---------TSGTVDFNFDNNAKISVPA 325 + D A A +D +T Q T G F NA+I Sbjct: 220 IASDAFAKYKKATGA--VADNNTGLLRLTTAQYANLQSLFFTIGGQTFELTANAQI---- 273 Query: 326 SEFTAPLSYANGQPYPKCQLLLGI--SDAN-----ILGDNFLRSAYLVYDLDDDKISL 376 + L+ A G L++G SD+ I G FL Y VYD + ++ L Sbjct: 274 --WPRNLNTAIGGSASSVYLIVGDLGSDSGEGLDFINGLTFLERFYSVYDTTNKRLGL 329 >3O9L-A nrPDB Length = 166 Score = 62.0 bits (149), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 45/160 (28%), Positives = 82/160 (51%), Gaps = 17/160 (10%) Query: 58 NNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTP 117 N Y +I IG+ Q F V+ DTGSS++WVP + C + C ++ Sbjct: 14 NYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSK--CSRLYTA-----CVYHKLFDA 66 Query: 118 KSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKT-SIP------ 170 S++ ++ GT + Y G+ S G L +D + GG ++T Q+F ++T+ ++P Sbjct: 67 SDSSSYKHNGTELTLRYSTGTVS-GFLSQDIITVGGITVT-QMFGEVTEMPALPFMLAEF 124 Query: 171 QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLN 210 G++G+G+ +A G + + +QGV+ ++ +S Y N Sbjct: 125 DGVVGMGF-IEQAIGRVTPIFDNIISQGVLKEDVFSFYYN 163 >3TPL-A nrPDB Length = 433 Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 69/281 (24%), Positives = 123/281 (43%), Gaps = 46/281 (16%) Query: 64 YAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTTS 123 Y ++T+GS Q N++VDTGSS+ V A P P Y + S+T Sbjct: 54 YYVEMTVGSPPQTLNILVDTGSSNFAVGAA------PHPFLHR-------YYQRQLSSTY 100 Query: 124 QNLGTPFYIGYGDGSSSQGTLYKDTVGF-GGASITKQV-FADITKT-------SIPQGIL 174 ++L Y+ Y G+ + G L D V G ++T + A IT++ S +GIL Sbjct: 101 RDLRKGVYVPYTQGAWA-GELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL 159 Query: 175 GIGYKTNEAAGDYDNVPVTLKN--QGVIAKNAYSLYLNSPN----------AATGQIIFG 222 G+ Y E A D++ + + N +SL L + G +I G Sbjct: 160 GLAYA--EIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIG 217 Query: 223 GVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNINGNI------DVLLDSGTTITYLQ 276 G+D + Y+GSL P+ + + + ++ G+++ + ++DSGTT L Sbjct: 218 GIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLP 277 Query: 277 QDVAQDIIDAFQAELKSDGQGHTFYVTD---CQTSGTVDFN 314 + V + + + +A ++ F++ + C +GT +N Sbjct: 278 KKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWN 318 >4OC6-B nrPDB Length = 243 Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 65/252 (25%), Positives = 111/252 (44%), Gaps = 38/252 (15%) Query: 152 GGASITKQVFADITK----TSIP---QGILGIGY---KTNEAAGDYDNVPVTLKNQGVIA 201 GG + +QVF + TK T I GILG+ Y N +DN L Q ++ Sbjct: 1 GGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDN----LMQQKLVD 56 Query: 202 KNAYSLYLNS-PNAATG-QIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLK-AVGKNI 258 +N +S YL+ P+A G +++ GG D Y GSL + VT ++ L+ ++ A G + Sbjct: 57 QNIFSFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTL 116 Query: 259 -NGNIDVLLDSGTTITYLQQDVAQDIIDAFQAELKSDGQGHTFYVTDCQTSGTVD-FNFD 316 + ++D+GT++ D +++ A A G+ Y+ C+ T+ Sbjct: 117 CKEGCEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGE----YMIPCEKVSTLPAITLK 172 Query: 317 NNAK-ISVPASEFTAPLSYANGQPYPKCQLLLGISDAN---------ILGDNFLRSAYLV 366 K + ++T +S A K L G + ILGD F+ Y V Sbjct: 173 LGGKGYKLSPEDYTLKVSQAG-----KTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTV 227 Query: 367 YDLDDDKISLAQ 378 +D D++++ A+ Sbjct: 228 FDRDNNRVGFAE 239 >4OD9-A nrPDB Length = 103 Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 42/104 (40%), Positives = 50/104 (48%), Gaps = 11/104 (10%) Query: 48 VKRQAIPVTLNNEH-VSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSA 106 V IP L N Y +I IG+ Q F V+ DTGSS+LWVP S+ C + Sbjct: 3 VTEGPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVP--SIHC------KLL 54 Query: 107 DF-CKGKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTV 149 D C Y S+T GT F I YG GS S G L +DTV Sbjct: 55 DIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLS-GYLSQDTV 97 >4B1C-A nrPDB Length = 375 Score = 45.1 bits (105), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 69/271 (25%), Positives = 121/271 (44%), Gaps = 40/271 (14%) Query: 64 YAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTTS 123 Y ++T+GS Q N++VDTGSS+ V A P P Y + S+T Sbjct: 20 YYVEMTVGSPPQTLNILVDTGSSNFAVGAA------PHPFLHR-------YYQRQLSSTY 66 Query: 124 QNLGTPFYIGYGDGSSSQGTLYKDTVGF-GGASITKQV-FADITKT-------SIPQGIL 174 ++L Y+ Y G +G L D V G ++T + A IT++ S +GIL Sbjct: 67 RDLRKGVYVPYTQG-KWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL 125 Query: 175 GIGYKTNEAAGDYDNVPVTLKN--QGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSGS 232 G+ Y E A D++ + + N +SL L G +I GG+D + Y+GS Sbjct: 126 GLAYA--EIARPDDSLEPFFDSLVKQTHVPNLFSLQL----CGGGSMIIGGIDHSLYTGS 179 Query: 233 LIAVPVTSDRELRITLNSLKAVGKNINGNI------DVLLDSGTTITYLQQDVAQDIIDA 286 L P+ + + + ++ G+++ + ++DSGTT L + V + + + Sbjct: 180 LWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKS 239 Query: 287 FQAELKSDGQGHTFYVTD---CQTSGTVDFN 314 +A ++ F++ + C +GT +N Sbjct: 240 IKAASSTEKFPDGFWLGEQLVCWQAGTTPWN 270 >3ZKX-A nrPDB Length = 386 Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 60/248 (24%), Positives = 110/248 (44%), Gaps = 42/248 (16%) Query: 64 YAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTTS 123 Y ++ IG+ QK ++VDTGSS+ V P D + + S+T Sbjct: 18 YYLEMLIGTPPQKLQILVDTGSSNFAVAGT--------PHSYID-----TYFDTERSSTY 64 Query: 124 QNLGTPFYIGYGDGSSSQGTLYKDTV----GFGGASITKQVFADITKTS---IP----QG 172 ++ G + Y GS + G + +D V GF + + A I ++ +P G Sbjct: 65 RSKGFDVTVKYTQGSWT-GFVGEDLVTIPKGFNTSFLVN--IATIFESENFFLPGIKWNG 121 Query: 173 ILGIGYKT-NEAAGDYDNVPVTLKNQGVIAKNAYSLYLNS---PNAAT----GQIIFGGV 224 ILG+ Y T + + + +L Q I N +S+ + P A + G ++ GG+ Sbjct: 122 ILGLAYATLAKPSSSLETFFDSLVTQANI-PNVFSMQMCGAGLPVAGSGTNGGSLVLGGI 180 Query: 225 DKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNINGNI------DVLLDSGTTITYLQQD 278 + + Y G + P+ + +I + L+ G+++N + ++DSGTT+ L Q Sbjct: 181 EPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQK 240 Query: 279 VAQDIIDA 286 V +++A Sbjct: 241 VFDAVVEA 248 >4ZL4-A nrPDB Length = 444 Score = 35.0 bits (79), Expect = 0.059, Method: Compositional matrix adjust. Identities = 59/289 (20%), Positives = 107/289 (37%), Gaps = 88/289 (30%) Query: 59 NEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTP- 117 +E+ Y DI IG+ +Q+ ++I+DTGSS L P A CK G++ Sbjct: 25 DEYAYYFLDIDIGTPEQRISLILDTGSSSLSFPCAG--------------CKNCGVHMEN 70 Query: 118 -----KSSTTS----QNLGTPFYI-----------GYGDGSSSQGTLYKDTVGFGGASIT 157 S T+S +N PF + Y +GS G + D V + Sbjct: 71 PFNLNNSKTSSILYCENEECPFKLNCVKGKCEYMQSYCEGSQISGFYFSDVVSVVSYNNE 130 Query: 158 KQVFADITKTSIPQ----------GILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSL 207 + F + + + G+LG+ + + N+ L + K +++ Sbjct: 131 RVTFRKLMGCHMHEESLFLYQQATGVLGMSLSKPQGIPTFVNL---LFDNAPQLKQVFTI 187 Query: 208 YLNSPNAATGQIIFGGVDKA----------------------------------KYSGSL 233 + S N G++I GG D A + + + Sbjct: 188 CI-SENG--GELIAGGYDPAYIVRRGGSKSVSGQGSGPVSESLSESGEDPQVALREAEKV 244 Query: 234 IAVPVTSDRELRITLNSLKAVGKNI---NGNIDVLLDSGTTITYLQQDV 279 + VT I + L G N+ + +++L+DSG+T T++ +D+ Sbjct: 245 VWENVTRKYYYYIKVRGLDMFGTNMMSSSKGLEMLVDSGSTFTHIPEDL 293 >5G5H-C nrPDB Length = 732 Score = 30.4 bits (67), Expect = 1.4, Method: Compositional matrix adjust. Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 8/105 (7%) Query: 187 YDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSGSLIAVPVTSDRELRI 246 +D + LK G A+ AY + +PNAA G I+ + K G L A+ + ++ Sbjct: 22 HDRIDGPLKTTGT-ARYAYEWHEEAPNAAYGYIVGSAIAK----GRLTALDTDAAQKAPG 76 Query: 247 TLNSLKAVGKNINGNID---VLLDSGTTITYLQQDVAQDIIDAFQ 288 L + A + G D L G TI + Q +A + + F+ Sbjct: 77 VLAVITASNAGVLGKGDKNTARLLGGPTIEHYHQAIALVVAETFE 121 >3CP8-A nrPDB Length = 641 Score = 29.6 bits (65), Expect = 2.5, Method: Compositional matrix adjust. Identities = 15/46 (32%), Positives = 21/46 (45%) Query: 182 EAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKA 227 E GD D VP + + V +N S YL T I+ G D++ Sbjct: 233 EQPGDVDPVPFSFSSTSVANRNLVSCYLTKTTEKTHDILRTGFDRS 278 >3LIZ-A nrPDB Length = 334 Score = 29.3 bits (64), Expect = 2.8, Method: Compositional matrix adjust. Identities = 13/36 (36%), Positives = 18/36 (50%) Query: 217 GQIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLK 252 G+IIFGG D G VP+ D + L+ +K Sbjct: 170 GEIIFGGSDWKYVDGEFTYVPLVGDDSWKFRLDGVK 205 >4WAD-A nrPDB Length = 498 Score = 29.3 bits (64), Expect = 3.4, Method: Compositional matrix adjust. Identities = 33/154 (21%), Positives = 60/154 (38%), Gaps = 31/154 (20%) Query: 169 IPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAK-----NAYSLYLNSPNAATGQIIFGG 223 IP I+ YK G+YD + LK QG + + N + + N Sbjct: 39 IPADIVTFDYK-----GNYDEIIKALKKQGKMDRRTKMYNVFEYFKQISN---------- 83 Query: 224 VDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDI 283 +K S L+ ++ + I + K + + + + +GT I Y+++ ++ + Sbjct: 84 -NKHFKSNKLLYKHISERLKNTIEIEESKGISRYFD------ITTGTYIAYIRKSKSEKV 136 Query: 284 IDAFQAELKSDGQGHTFYVTDCQTSGTVDFNFDN 317 ID F K + + F D + FN DN Sbjct: 137 IDFF----KDNKRIERFSFIDNKVHMKETFNVDN 166 >3FG6-A nrPDB Length = 371 Score = 28.5 bits (62), Expect = 5.1, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 4/67 (5%) Query: 308 SGTVD-FNFDNNAKISVPAS---EFTAPLSYANGQPYPKCQLLLGISDANILGDNFLRSA 363 SG V+ + +NN +I V + EF Y YP+ Q++ AN D SA Sbjct: 51 SGKVEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTYPRGQIIYTWQGANATRDELTTSA 110 Query: 364 YLVYDLD 370 +L LD Sbjct: 111 FLTVQLD 117 >6BYQ-A nrPDB Length = 410 Score = 28.5 bits (62), Expect = 5.1, Method: Compositional matrix adjust. Identities = 12/28 (42%), Positives = 18/28 (64%) Query: 54 PVTLNNEHVSYAADITIGSNKQKFNVIV 81 P+ + V+ ADI +G N QKFN++V Sbjct: 183 PLLQGYDSVAMGADIELGGNDQKFNLLV 210 >5UOG-A nrPDB Length = 344 Score = 28.5 bits (62), Expect = 5.2, Method: Compositional matrix adjust. Identities = 32/105 (30%), Positives = 45/105 (42%), Gaps = 11/105 (10%) Query: 152 GGASITKQVFADITKTSIPQGIL---GIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLY 208 G AS K V AD+ P+G+L G G +EAA VT G IA ++ Sbjct: 225 GTASTLKAVNADVLSALGPKGVLINVGRGSTVDEAA------LVTALQNGTIAGAGLDVF 278 Query: 209 LNSPNAATGQIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKA 253 N PN + F V + S A VT + + +++LKA Sbjct: 279 ENEPNVPEALLSFPNVSLLPHVAS--ASVVTRNAMSDLVVDNLKA 321 >1LPA-B nrPDB Length = 449 Score = 28.1 bits (61), Expect = 6.7, Method: Compositional matrix adjust. Identities = 14/56 (25%), Positives = 24/56 (42%) Query: 109 CKGKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADI 164 C G Y + + ++G FY+ GD S+ YK +V G +T + + Sbjct: 305 CPQMGHYADRYPGKTNDVGQKFYLDTGDASNFARWRYKVSVTLSGKKVTGHILVSL 360 >3OAD-B nrPDB Length = 176 Score = 28.1 bits (61), Expect = 6.9, Method: Compositional matrix adjust. Identities = 37/177 (20%), Positives = 73/177 (41%), Gaps = 23/177 (12%) Query: 217 GQIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKN---INGNIDVLLDSGTTIT 273 GQI+ GG D Y G+ + + +I + + +VG + L+D+G + Sbjct: 4 GQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGV-SVGSSTLLCEDGCLALVDTGASYI 62 Query: 274 YLQQDVAQDIIDAFQAELKSDGQGHTF-YVTDCQTSGTV-DFNFDNNAK-ISVPASEFTA 330 + +++A A+ + F YV C T+ D +F K ++ ++++ Sbjct: 63 SGSTSSIEKLMEALGAKKR------LFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVF 116 Query: 331 PLSYANGQPYPKCQLLLGISD-------ANILGDNFLRSAYLVYDLDDDKISLAQVK 380 SY++ + C L + D LG F+R Y +D +++I A + Sbjct: 117 QESYSSKK---LCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR 170 >3K10-A nrPDB Length = 179 Score = 27.7 bits (60), Expect = 8.4, Method: Compositional matrix adjust. Identities = 15/42 (35%), Positives = 25/42 (59%), Gaps = 5/42 (11%) Query: 155 SITKQVFADITKTSIPQGILGIGYKTNEAAGDYDNVPVTLKN 196 S+ K+ F D+ + QG++G+ KT+E +D +P LKN Sbjct: 55 SLEKEAFRDLVNRLVSQGLIGLKDKTSET---FDLLP--LKN 91 >1HPL-A nrPDB Length = 449 Score = 27.7 bits (60), Expect = 8.7, Method: Compositional matrix adjust. Identities = 15/60 (25%), Positives = 26/60 (43%) Query: 105 SADFCKGKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADI 164 S++ C G Y + ++ +G FY+ GD S+ Y+ V G +T V + Sbjct: 301 SSEGCPQMGHYADRFPGRTKGVGQLFYLNTGDASNFARWRYRVDVTLSGKKVTGHVLVSL 360 >5MYJ-A nrPDB Length = 185 Score = 27.7 bits (60), Expect = 9.2, Method: Compositional matrix adjust. Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 1/35 (2%) Query: 277 QDVAQDIIDAFQAELKSDGQGHTFYV-TDCQTSGT 310 + VA +DA +A L+ D GH FYV TD ++GT Sbjct: 134 KHVALKPMDAEEAVLQMDMLGHDFYVFTDADSNGT 168 >4WJ3-M nrPDB Length = 599 Score = 27.7 bits (60), Expect = 9.6, Method: Compositional matrix adjust. Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 3/78 (3%) Query: 152 GGASITKQVFADITKTSIPQGILGIGY-KTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLN 210 G AS+ + D TK G G+ Y K NE A + + + I + ++ L+ Sbjct: 336 GAASMPRSQIDDYTKFVGIYGAKGLAYIKVNERAKGVEGLQSPIVK--FIPEANLNVILD 393 Query: 211 SPNAATGQIIFGGVDKAK 228 A G I+F G DKAK Sbjct: 394 RVGAVDGDIVFFGADKAK 411 >5MP7-A nrPDB Length = 326 Score = 27.7 bits (60), Expect = 9.9, Method: Compositional matrix adjust. Identities = 36/167 (21%), Positives = 72/167 (43%), Gaps = 24/167 (14%) Query: 146 KDTVGFGGASITKQVFADITKTSIPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAY 205 +D G I+ ++ AD+ KT+ I+ + T++ G +D ++ Q ++ Sbjct: 105 QDKKHRGREPISARLVADLLKTAGADRIVSVDLHTDQIQGFFDGPVDHMRAQKLLTGYIG 164 Query: 206 SLYLN------SPNAATGQIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNIN 259 Y + SP++ ++ K++ SL VP+ + R L + + Sbjct: 165 EHYADEDMVVVSPDSGRVRV------AEKWADSLGGVPLAFIHKTRDPLVPNQVKSNRVV 218 Query: 260 GNI--------DVLLDSGTTIT----YLQQDVAQDIIDAFQAELKSD 294 G++ D ++D+G TI L++D A+D+I A + SD Sbjct: 219 GDVKGKTCILTDDMIDTGGTIAGAVNLLREDGAKDVIIAATHGVLSD 265 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2QZW-A nrPDB 420 e-118 3PVK-A nrPDB 380 e-106 2H6T-A nrPDB 368 e-102 2QZX-A nrPDB 362 e-100 5UX4-A nrPDB 346 8e-96 1J71-A nrPDB 333 1e-91 2PSG-A nrPDB 319 1e-87 1PSO-E nrPDB 317 6e-87 5MKT-A nrPDB 315 2e-86 1TZS-A nrPDB 311 2e-85 3FV3-A nrPDB 311 5e-85 5MLG-A nrPDB 309 1e-84 4AA9-A nrPDB 309 1e-84 1AM5-A nrPDB 309 2e-84 4Y9W-A nrPDB 309 2e-84 5NFG-A nrPDB 308 2e-84 4PEP-A nrPDB 308 4e-84 1SMR-A nrPDB 305 2e-83 2BJU-A nrPDB 304 5e-83 5N71-A nrPDB 303 1e-82 4AMT-A nrPDB 302 2e-82 1MIQ-A nrPDB 301 5e-82 4CMS-A nrPDB 301 5e-82 5BWY-A nrPDB 300 6e-82 2ANL-A nrPDB 298 3e-81 1XDH-A nrPDB 297 6e-81 1QS8-A nrPDB 297 6e-81 3VCM-A nrPDB 296 7e-81 5JOD-A nrPDB 293 6e-80 5I70-B nrPDB 293 9e-80 1FMX-A nrPDB 291 5e-79 3QS1-A nrPDB 290 9e-79 1AVF-A nrPDB 289 2e-78 3QVI-A nrPDB 273 7e-74 3FNT-A nrPDB 268 3e-72 1UH8-A nrPDB 258 3e-69 1QDM-A nrPDB 252 2e-67 2ASI-A nrPDB 241 3e-64 1B5F-A nrPDB 240 7e-64 1IBQ-A nrPDB 229 2e-60 1IZE-A nrPDB 224 4e-59 1MPP-A nrPDB 223 1e-58 3TPL-A nrPDB 221 3e-58 1PPK-E nrPDB 221 3e-58 4OC6-B nrPDB 219 2e-57 5HCT-A nrPDB 211 5e-55 4B1C-A nrPDB 207 6e-54 3EMY-A nrPDB 204 6e-53 3ZKX-A nrPDB 201 3e-52 3PI0-A nrPDB 198 3e-51 1WKR-A nrPDB 179 2e-45 3O9L-A nrPDB 159 3e-39 4OD9-A nrPDB 121 5e-28 Sequences not found previously or not previously below threshold: 3OAD-B nrPDB 145 3e-35 3LIZ-A nrPDB 129 3e-30 4ZL4-A nrPDB 87 9e-18 1B5F-B nrPDB 63 3e-10 4PPH-A nrPDB 45 8e-05 3AUP-A nrPDB 43 2e-04 2BKL-A nrPDB 30 1.3 1QU3-A nrPDB 30 1.7 4WJ3-M nrPDB 30 2.4 1T6G-A nrPDB 29 3.8 1EBD-A nrPDB 29 4.0 4LUJ-A nrPDB 28 5.1 3U14-A nrPDB 28 5.1 3Q31-A nrPDB 28 5.1 3CP8-A nrPDB 28 5.8 >2QZW-A nrPDB Length = 341 Score = 420 bits (1081), Expect = e-118, Method: Composition-based stats. Identities = 341/341 (100%), Positives = 341/341 (100%) Query: 51 QAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCK 110 QAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCK Sbjct: 1 QAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCK 60 Query: 111 GKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP 170 GKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP Sbjct: 61 GKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP 120 Query: 171 QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYS 230 QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYS Sbjct: 121 QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYS 180 Query: 231 GSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAE 290 GSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAE Sbjct: 181 GSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAE 240 Query: 291 LKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGIS 350 LKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGIS Sbjct: 241 LKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGIS 300 Query: 351 DANILGDNFLRSAYLVYDLDDDKISLAQVKYTSASNIAALT 391 DANILGDNFLRSAYLVYDLDDDKISLAQVKYTSASNIAALT Sbjct: 301 DANILGDNFLRSAYLVYDLDDDKISLAQVKYTSASNIAALT 341 >3PVK-A nrPDB Length = 342 Score = 380 bits (975), Expect = e-106, Method: Composition-based stats. Identities = 253/342 (73%), Positives = 281/342 (82%), Gaps = 1/342 (0%) Query: 51 QAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCK 110 QA+PVTL+NE V+YAADIT+GSN QK NVIVDTGSSDLWVPD +V C Q+ADFCK Sbjct: 1 QAVPVTLHNEQVTYAADITVGSNNQKLNVIVDTGSSDLWVPDVNVDCQVTYSDQTADFCK 60 Query: 111 GKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP 170 KG Y P S+ SQ+L TPF IGYGDGSSSQGTLYKDTVGFGG SI QV AD+ TSI Sbjct: 61 QKGTYDPSGSSASQDLNTPFKIGYGDGSSSQGTLYKDTVGFGGVSIKNQVLADVDSTSID 120 Query: 171 QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYS 230 QGILG+GYKTNEA G YDNVPVTLK QGVIAKNAYSLYLNSP+AATGQIIFGGVD AKYS Sbjct: 121 QGILGVGYKTNEAGGSYDNVPVTLKKQGVIAKNAYSLYLNSPDAATGQIIFGGVDNAKYS 180 Query: 231 GSLIAVPVTSDRELRITLNSLKAVGKNIN-GNIDVLLDSGTTITYLQQDVAQDIIDAFQA 289 GSLIA+PVTSDRELRI+L S++ GK IN N+DVLLDSGTTITYLQQD+A II AF Sbjct: 181 GSLIALPVTSDRELRISLGSVEVSGKTINTDNVDVLLDSGTTITYLQQDLADQIIKAFNG 240 Query: 290 ELKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGI 349 +L D G++FY DC SG V FNF NAKISVPASEF A L +GQPY KCQLL + Sbjct: 241 KLTQDSNGNSFYEVDCNLSGDVVFNFSKNAKISVPASEFAASLQGDDGQPYDKCQLLFDV 300 Query: 350 SDANILGDNFLRSAYLVYDLDDDKISLAQVKYTSASNIAALT 391 +DANILGDNFLRSAY+VYDLDD++ISLAQVKYTSAS+I+ALT Sbjct: 301 NDANILGDNFLRSAYIVYDLDDNEISLAQVKYTSASSISALT 342 >2H6T-A nrPDB Length = 340 Score = 368 bits (944), Expect = e-102, Method: Composition-based stats. Identities = 239/341 (70%), Positives = 281/341 (82%), Gaps = 1/341 (0%) Query: 51 QAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCK 110 Q +PV L NE VSYA+DIT+GSNKQK V++DTGSSDLWVPD+ V+C GQ +FCK Sbjct: 1 QTVPVKLINEQVSYASDITVGSNKQKLTVVIDTGSSDLWVPDSQVSCQ-AGQGQDPNFCK 59 Query: 111 GKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP 170 +G Y+P SS++SQNL +PF I YGDG++SQGT YKDT+GFGG SITKQ FAD+T TS+ Sbjct: 60 NEGTYSPSSSSSSQNLNSPFSIEYGDGTTSQGTWYKDTIGFGGISITKQQFADVTSTSVD 119 Query: 171 QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYS 230 QGILGIGYKT+EA G+YDNVPVTLKNQG+I+KNAYSLYLNS A +GQIIFGGVD AKYS Sbjct: 120 QGILGIGYKTHEAEGNYDNVPVTLKNQGIISKNAYSLYLNSRQATSGQIIFGGVDNAKYS 179 Query: 231 GSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAE 290 G+LIA+PVTSD ELRI LN++K G++IN ++DVLLDSGTTITYLQQ VA +I AF + Sbjct: 180 GTLIALPVTSDNELRIHLNTVKVAGQSINADVDVLLDSGTTITYLQQGVADQVISAFNGQ 239 Query: 291 LKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGIS 350 D G+ FY+ DC SG+VDF FD NAKISVPASEFTAPL +GQ Y +CQLL G S Sbjct: 240 ETYDANGNLFYLVDCNLSGSVDFAFDKNAKISVPASEFTAPLYTEDGQVYDQCQLLFGTS 299 Query: 351 DANILGDNFLRSAYLVYDLDDDKISLAQVKYTSASNIAALT 391 D NILGDNFLRSAY+VYDLDD++ISLAQVKYT+ASNIAALT Sbjct: 300 DYNILGDNFLRSAYIVYDLDDNEISLAQVKYTTASNIAALT 340 >2QZX-A nrPDB Length = 342 Score = 362 bits (930), Expect = e-100, Method: Composition-based stats. Identities = 196/341 (57%), Positives = 258/341 (75%), Gaps = 1/341 (0%) Query: 51 QAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCK 110 + VTL+NE ++Y ADIT+GS+ QK NVIVDTGSSDLW+PD++V C G DFCK Sbjct: 1 GPVAVTLHNEAITYTADITVGSDNQKLNVIVDTGSSDLWIPDSNVICIPKWRGDKGDFCK 60 Query: 111 GKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP 170 G Y+P SS TSQNL T F I YGDGS ++G LYKDTVG GG S+ Q+FA++ TS Sbjct: 61 SAGSYSPASSRTSQNLNTRFDIKYGDGSYAKGKLYKDTVGIGGVSVRDQLFANVWSTSAR 120 Query: 171 QGILGIGYKTNEAAG-DYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKY 229 +GILGIG+++ EA DYDN+P++L+NQG+I K AYSLYLNS A+TGQIIFGG+DKAKY Sbjct: 121 KGILGIGFQSGEATEFDYDNLPISLRNQGIIGKAAYSLYLNSAEASTGQIIFGGIDKAKY 180 Query: 230 SGSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQA 289 SGSL+ +P+TS+++L + L S+ G+N++ N +VLLDSGTTI+Y + + ++I+ A A Sbjct: 181 SGSLVDLPITSEKKLTVGLRSVNVRGRNVDANTNVLLDSGTTISYFTRSIVRNILYAIGA 240 Query: 290 ELKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGI 349 ++K D G+ YV DC+TSGT+DF F NN KISVP SEF Y +G+P+PKC++ + Sbjct: 241 QMKFDSAGNKVYVADCKTSGTIDFQFGNNLKISVPVSEFLFQTYYTSGKPFPKCEVRIRE 300 Query: 350 SDANILGDNFLRSAYLVYDLDDDKISLAQVKYTSASNIAAL 390 S+ NILGDNFLRSAY+VY+LDD KIS+A VKYTS S+I A+ Sbjct: 301 SEDNILGDNFLRSAYVVYNLDDKKISMAPVKYTSESDIVAI 341 >5UX4-A nrPDB Length = 420 Score = 346 bits (888), Expect = 8e-96, Method: Composition-based stats. Identities = 93/371 (25%), Positives = 152/371 (40%), Gaps = 38/371 (10%) Query: 34 VIKTPVNATGQEG--KVKRQAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVP 91 ++K P+ + + K + N Y +I IG+ Q F V+ DTGSS+LWVP Sbjct: 46 ILKGPITKYSMQSSPRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVP 105 Query: 92 DASVTCDKPRPGQSADFCKGKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGF 151 S+ C C Y S+T GT F I YG GS S G L +DTV Sbjct: 106 --SIHCKLL-----DIACWVHHKYNSDKSSTYVKNGTSFDIHYGSGSLS-GYLSQDTVSV 157 Query: 152 ------GGASITKQVFADITKTSI-------PQGILGIGYKTNEAAGDYDNVPVTLKNQG 198 GG + KQ+F + TK GILG+GY + + V L Q Sbjct: 158 PCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGILGMGYPFI-SVNNVLPVFDNLMKQK 216 Query: 199 VIAKNAYSLYLNSPNAA--TGQIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVG- 255 ++ KN +S YLN G+++ GG D Y G L + VT ++ ++ L+ Sbjct: 217 LVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSE 276 Query: 256 -KNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAELKSDGQGHTFYVTDCQTSGTVD-F 313 G + ++D+GT++ D +++ A A G+ Y+ C+ ++ Sbjct: 277 LTLCKGGCEAIVDTGTSLLVGPVDEVKELQKAIGAVPLIQGE----YMIPCEKVSSLPII 332 Query: 314 NFDNNAK-ISVPASEFTAPLS----YANGQPYPKCQLLLGISDANILGDNFLRSAYLVYD 368 F + + ++ +S + + ILGD F+ Y V+D Sbjct: 333 TFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFD 392 Query: 369 LDDDKISLAQV 379 + +++ A+ Sbjct: 393 REYNRVGFAKA 403 >1J71-A nrPDB Length = 334 Score = 333 bits (853), Expect = 1e-91, Method: Composition-based stats. Identities = 187/341 (54%), Positives = 232/341 (68%), Gaps = 8/341 (2%) Query: 51 QAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCK 110 +P TL NE SYAADI +GSN+QK V++DTGSSDLWV D C GQ+ +FCK Sbjct: 1 SDVPTTLINEGPSYAADIVVGSNQQKQTVVIDTGSSDLWVVDTDAECQVTYSGQTNNFCK 60 Query: 111 GKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP 170 +G + P SS+++QNL F I YGD +SSQG+ YKDTVGFGG SI Q FAD+T TS+ Sbjct: 61 QEGTFDPSSSSSAQNLNQDFSIEYGDLTSSQGSFYKDTVGFGGISIKNQQFADVTTTSVD 120 Query: 171 QGILGIGYKTNEAAGD-YDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKY 229 QGI+GIG+ +EA + YDNVPVTLK QG+I KNAYSLYLNS +A+TG+IIFGGVD AKY Sbjct: 121 QGIMGIGFTADEAGYNLYDNVPVTLKKQGIINKNAYSLYLNSEDASTGKIIFGGVDNAKY 180 Query: 230 SGSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQA 289 +G+L A+PVTS ELR+ L S+ G +++ N DV+LDSGTTITY Q A A Sbjct: 181 TGTLTALPVTSSVELRVHLGSINFDGTSVSTNADVVLDSGTTITYFSQSTADKFARIVGA 240 Query: 290 ELKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGI 349 D + + + C SG FNFD KI+VP SE S ++ C + Sbjct: 241 --TWDSRNEIYRLPSCDLSGDAVFNFDQGVKITVPLSELILKDSDSS-----ICYFGISR 293 Query: 350 SDANILGDNFLRSAYLVYDLDDDKISLAQVKYTSASNIAAL 390 +DANILGDNFLR AY+VYDLDD ISLAQVKYTS+S+I+AL Sbjct: 294 NDANILGDNFLRRAYIVYDLDDKTISLAQVKYTSSSDISAL 334 >2PSG-A nrPDB Length = 370 Score = 319 bits (817), Expect = 1e-87, Method: Composition-based stats. Identities = 105/362 (29%), Positives = 164/362 (45%), Gaps = 31/362 (8%) Query: 33 DVIKT----PVNATGQEGKVKRQAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDL 88 D +KT P + E P+ N Y I IG+ Q F VI DTGSS+L Sbjct: 24 DFLKTHKHNPASKYFPEAAALIGDEPL-ENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNL 82 Query: 89 WVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDT 148 WVP SV C S+ C + P S+T + I YG GS + G L DT Sbjct: 83 WVP--SVYC-------SSLACSDHNQFNPDDSSTFEATSQELSITYGTGSMT-GILGYDT 132 Query: 149 VGFGGASITKQVFADITKTSI-------PQGILGIGYKTNEAAGDYDNVPVTLKNQGVIA 201 V GG S T Q+F GILG+ Y + A+G V L +QG+++ Sbjct: 133 VQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISASGA-TPVFDNLWDQGLVS 191 Query: 202 KNAYSLYLNSPNAATGQIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKN--IN 259 ++ +S+YL+S + + ++ GG+D + Y+GSL VPV+ + +ITL+S+ G+ + Sbjct: 192 QDLFSVYLSSNDDSGSVVLLGGIDSSYYTGSLNWVPVSVEGYWQITLDSITMDGETIACS 251 Query: 260 GNIDVLLDSGTTITYLQQDVAQDIIDAFQAELKSDGQGHTFYVTDCQTSGT-VDFNFD-N 317 G ++D+GT++ +I A SDG+ V C + + D F + Sbjct: 252 GGCQAIVDTGTSLLTGPTSAIANIQSDIGASENSDGE----MVISCSSIDSLPDIVFTID 307 Query: 318 NAKISVPASEFTAPLSYANGQPYPKCQLLLGISDANILGDNFLRSAYLVYDLDDDKISLA 377 + + S + + + + + ILGD F+R Y V+D ++K+ LA Sbjct: 308 GVQYPLSPSAYILQDDDSCTSGFEGMDVPTSSGELWILGDVFIRQYYTVFDRANNKVGLA 367 Query: 378 QV 379 V Sbjct: 368 PV 369 >1PSO-E nrPDB Length = 326 Score = 317 bits (812), Expect = 6e-87, Method: Composition-based stats. Identities = 101/333 (30%), Positives = 156/333 (46%), Gaps = 26/333 (7%) Query: 58 NNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTP 117 N + Y I IG+ Q F V+ DTGSS+LWVP SV C S+ C + P Sbjct: 8 NYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVP--SVYC-------SSLACTNHNRFNP 58 Query: 118 KSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSI-------P 170 + S+T Q+ I YG GS + G L DTV GG S T Q+F Sbjct: 59 EDSSTYQSTSETVSITYGTGSMT-GILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPF 117 Query: 171 QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYS 230 GILG+ Y + ++G V + NQG+++++ +S+YL++ + + +IFGG+D + Y+ Sbjct: 118 DGILGLAYPSISSSGA-TPVFDNIWNQGLVSQDLFSVYLSADDQSGSVVIFGGIDSSYYT 176 Query: 231 GSLIAVPVTSDRELRITLNSLKAVGK--NINGNIDVLLDSGTTITYLQQDVAQDIIDAFQ 288 GSL VPVT + +IT++S+ G+ ++D+GT++ +I Sbjct: 177 GSLNWVPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIANIQSDIG 236 Query: 289 AELKSDGQGHTFYVTDCQT-SGTVDFNFD-NNAKISVPASEFTAPLSYANGQPYPKCQLL 346 A SDG V C S D F N + VP S + + + L Sbjct: 237 ASENSDGD----MVVSCSAISSLPDIVFTINGVQYPVPPSAYILQSEGSCISGFQGMNLP 292 Query: 347 LGISDANILGDNFLRSAYLVYDLDDDKISLAQV 379 + ILGD F+R + V+D ++++ LA V Sbjct: 293 TESGELWILGDVFIRQYFTVFDRANNQVGLAPV 325 >5MKT-A nrPDB Length = 389 Score = 315 bits (807), Expect = 2e-86, Method: Composition-based stats. Identities = 90/345 (26%), Positives = 155/345 (44%), Gaps = 36/345 (10%) Query: 55 VTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGI 114 V N + Y +I IG+ Q F VI DTGS++LWVP S C + C + Sbjct: 54 VLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVP--STKCSRLYL-----ACGIHSL 106 Query: 115 YTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSI----- 169 Y S++ G+ F I YG G +G L +D+V GG ++T Q F ++T+ + Sbjct: 107 YESSDSSSYMENGSDFTIHYGSG-RVKGFLSQDSVTVGGITVT-QTFGEVTELPLIPFML 164 Query: 170 --PQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNS-PNAATGQIIFGGVDK 226 G+LG+G+ +A G V + +QGV+ + +S+Y N + G+++ GG D Sbjct: 165 AKFDGVLGMGFPA-QAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDP 223 Query: 227 AKYSGSLIAVPVTSDRELRITLNSLKAVGKN--INGNIDVLLDSGTTITYLQQDVAQDII 284 Y G+ V ++ +IT+ + V++D+G++ + I+ Sbjct: 224 QHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIM 283 Query: 285 DAFQAELKSDGQGHTFYVTDCQTSGT-VDFNFDNNAK-ISVPASEFTAPLSYANGQPYPK 342 A A+ K + YV +C T D +FD + ++ ++++ L Y N + Sbjct: 284 QALGAKEKRIEE----YVVNCSQVPTLPDISFDLGGRAYTLSSTDYV--LQYPNRRD-KL 336 Query: 343 CQLLLGISDA-------NILGDNFLRSAYLVYDLDDDKISLAQVK 380 C L L D +LG F+R Y +D +++I A + Sbjct: 337 CTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 381 >1TZS-A nrPDB Length = 351 Score = 311 bits (798), Expect = 2e-85, Method: Composition-based stats. Identities = 102/357 (28%), Positives = 155/357 (43%), Gaps = 43/357 (12%) Query: 43 GQEGKVKRQAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRP 102 + K I N + Y I+IGS Q F VI DTGSS+LWVP SV C P Sbjct: 8 SMDQSAKEPLI----NYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVP--SVYCTSP-- 59 Query: 103 GQSADFCKGKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFA 162 CK + P S+T G F I YG GS S G + D V G ++ Q F Sbjct: 60 -----ACKTHSRFQPSQSSTYSQPGQSFSIQYGTGSLS-GIIGADQVSVEGLTVVGQQFG 113 Query: 163 D-ITK------TSIPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYL--NSPN 213 + +T+ + GILG+GY + A G V + Q ++ +S+Y+ N Sbjct: 114 ESVTEPGQTFVDAEFDGILGLGYPS-LAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEG 172 Query: 214 AATGQIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKN--INGNIDVLLDSGTT 271 A ++IFGG D + +SGSL VPVT +I L++++ G + ++D+GT+ Sbjct: 173 GAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTS 232 Query: 272 ITYLQQDVAQDIIDAFQAELKSDGQGHTFYVTDCQTSGT-VDFNFD-NNAKISVPASEFT 329 + D + + +A A Y +C D F N ++ + +T Sbjct: 233 LITGPSDKIKQLQNAIGAAPV-----DGEYAVECANLNVMPDVTFTINGVPYTLSPTAYT 287 Query: 330 APLSYANGQPYPKCQLLLGISD-------ANILGDNFLRSAYLVYDLDDDKISLAQV 379 L + +G + C D ILGD F+R Y V+D ++++ LA Sbjct: 288 L-LDFVDGMQF--CSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPA 341 >3FV3-A nrPDB Length = 339 Score = 311 bits (796), Expect = 5e-85, Method: Composition-based stats. Identities = 178/350 (50%), Positives = 220/350 (62%), Gaps = 23/350 (6%) Query: 52 AIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKG 111 +I ++L NE SYA+ +++GSNKQ+ VI+DTGSSD WV D++ C K CK Sbjct: 2 SISLSLINEGPSYASKVSVGSNKQQQTVIIDTGSSDFWVVDSNAQCGKGVD------CKS 55 Query: 112 KGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIPQ 171 G +TP SS++ +NLG F I YGDGS+SQGT KDTV G SIT Q AD+T+TS+ Q Sbjct: 56 SGTFTPSSSSSYKNLGAAFTIRYGDGSTSQGTWGKDTVTINGVSITGQQIADVTQTSVDQ 115 Query: 172 GILGIGYKTNEAAGD---------YDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFG 222 GILGIGY +NEA D YDNVPVTLK QG I NAYSLYLNSP+A TG IIFG Sbjct: 116 GILGIGYTSNEAVYDTSGRQTTPNYDNVPVTLKKQGKIRTNAYSLYLNSPSAETGTIIFG 175 Query: 223 GVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQD 282 GVD AKYSG L+A VTS + L I+L S+ G + + LLDSGTT+TY D A Sbjct: 176 GVDNAKYSGKLVAEQVTSSQALTISLASVNLKGSSFSFGDGALLDSGTTLTYFPSDFAAQ 235 Query: 283 IIDAFQAELKSDGQGHTFYVTDCQ--TSGTVDFNFDNNAKISVPASEFTAPLSYANGQPY 340 + D A L + Y DC TSGT FNF N AKI+VP +E+ Sbjct: 236 LADKAGARLVQVARDQYLYFIDCNTDTSGTTVFNFGNGAKITVPNTEYVYQ------NGD 289 Query: 341 PKCQLLLGISDANILGDNFLRSAYLVYDLDDDKISLAQVKYTSASNIAAL 390 C + SD ILGDNFLR AYL+Y+LD + IS+AQVKYT+ S+I+A+ Sbjct: 290 GTCLWGIQPSDDTILGDNFLRHAYLLYNLDANTISIAQVKYTTDSSISAV 339 >5MLG-A nrPDB Length = 389 Score = 309 bits (792), Expect = 1e-84, Method: Composition-based stats. Identities = 79/342 (23%), Positives = 135/342 (39%), Gaps = 30/342 (8%) Query: 55 VTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGI 114 V N Y +I IG+ Q F VI DTGS++LWVP G C+ + Sbjct: 54 VLTNYLDTQYYGEIGIGTPSQTFKVIFDTGSANLWVPSTKC-------GPLYTACEIHNL 106 Query: 115 YTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSI----- 169 Y S++ GT F I YG G +G L +D V GG +T Q F ++T+ + Sbjct: 107 YDSSESSSYMENGTEFTIHYGSG-KVKGFLSQDVVTVGGIIVT-QTFGEVTELPLIPFML 164 Query: 170 --PQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSP-NAATGQIIFGGVDK 226 G+LG+G+ G V + +Q V+ + +S+Y + + G+++ GG D Sbjct: 165 AKFDGVLGMGFPAQAVDGVI-PVFDHILSQRVLKEEVFSVYYSRESHLLGGEVVLGGSDP 223 Query: 227 AKYSGSLIAVPVTSDRELRITLNSLKAVGKN--INGNIDVLLDSGTTITYLQQDVAQDII 284 Y G+ V ++ +IT+ + ++D+GT+ Q I+ Sbjct: 224 QHYQGNFHYVSISKAGSWQITMKGVSVGPATLLCEEGCMAVVDTGTSYISGPTSSLQLIM 283 Query: 285 DAFQAELKSDGQGHTFYVTDCQTSGT-VDFNFDNNAK-ISVPASEFT----APLSYANGQ 338 A + K YV +C T D +F + ++ ++ Sbjct: 284 QALGVKEKRANN----YVVNCSQVPTLPDISFYLGGRTYTLSNMDYVQKNPFRNDDLCIL 339 Query: 339 PYPKCQLLLGISDANILGDNFLRSAYLVYDLDDDKISLAQVK 380 + +LG F+R Y +D +++I A + Sbjct: 340 ALQGLDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 381 >4AA9-A nrPDB Length = 320 Score = 309 bits (792), Expect = 1e-84, Method: Composition-based stats. Identities = 90/337 (26%), Positives = 148/337 (43%), Gaps = 32/337 (9%) Query: 54 PVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKG 113 P+T Y I IG+ Q+F V+ DTGSSDLWVP S+ C ++ CK Sbjct: 4 PLTS-YLDSQYFGKIYIGTPPQEFTVVFDTGSSDLWVP--SIYC-------KSNVCKNHH 53 Query: 114 IYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVF-------ADITK 166 + P+ S+T +NLG P I YG GS +G L DTV Q ++ Sbjct: 54 RFDPRKSSTFRNLGKPLSIHYGTGSM-EGFLGYDTVTVSNIVDPNQTVGLSTEQPGEVFT 112 Query: 167 TSIPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDK 226 S GILG+ Y + + V + ++ ++A++ +S+Y++ N + G +D Sbjct: 113 YSEFDGILGLAYPSLASEYSV-PVFDNMMDRHLVARDLFSVYMDR-NGQGSMLTLGAIDP 170 Query: 227 AKYSGSLIAVPVTSDRELRITLNSLKAVG--KNINGNIDVLLDSGTTITYLQQDVAQDII 284 + Y+GSL VPVT + + T++S+ G G +LD+GT++ + I Sbjct: 171 SYYTGSLHWVPVTLQQYWQFTVDSVTINGVAVACVGGCQAILDTGTSVLFGPSSDILKIQ 230 Query: 285 DAFQAELKSDGQGHTFYVTDCQTSGTVDFNF--DNNAKISVPASEFTAPLSYANGQPYPK 342 A A G+ +C ++ N + S +T+ + Sbjct: 231 MAIGATENRYGEFD----VNCGNLRSMPTVVFEINGRDYPLSPSAYTSKDQGFCTSGFQG 286 Query: 343 CQLLLGISDANILGDNFLRSAYLVYDLDDDKISLAQV 379 S+ ILGD F+R Y V+D ++++ LA+ Sbjct: 287 D----NNSELWILGDVFIREYYSVFDRANNRVGLAKA 319 >1AM5-A nrPDB Length = 324 Score = 309 bits (791), Expect = 2e-84, Method: Composition-based stats. Identities = 85/332 (25%), Positives = 140/332 (42%), Gaps = 26/332 (7%) Query: 58 NNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTP 117 N Y I+IG+ + F VI DTGSS+LWV + + C + P Sbjct: 8 NEADTEYYGVISIGTPPESFKVIFDTGSSNLWVSSSHCSAQ---------ACSNHNKFKP 58 Query: 118 KSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP------- 170 + S+T G + YG G +G L +DTV GG S Q + P Sbjct: 59 RQSSTYVETGKTVDLTYGTGGM-RGILGQDTVSVGGGSDPNQELGESQTEPGPFQAAAPF 117 Query: 171 QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYS 230 GILG+ Y + AAG V + +Q ++ K+ +S YL+ A +++ GGVD + Y+ Sbjct: 118 DGILGLAYPSIAAAGAV-PVFDNMGSQSLVEKDLFSFYLSGGGANGSEVMLGGVDNSHYT 176 Query: 231 GSLIAVPVTSDRELRITLNSLKAVGKNIN-GNIDVLLDSGTTITYLQQDVAQDIIDAFQA 289 GS+ +PVT+++ ++ L+ + G+ ++D+GT+ +I+ A Sbjct: 177 GSIHWIPVTAEKYWQVALDGITVNGQTAACEGCQAIVDTGTSKIVAPVSALANIMKDIGA 236 Query: 290 ELKSDGQGHTFYVTDCQTS-GTVDFNFD-NNAKISVPASEFTAPLSYANGQPYPKCQLLL 347 + +C + D F N K +P S + + Sbjct: 237 SEN-----QGEMMGNCASVQSLPDITFTINGVKQPLPPSAYIEGDQAFCTSGLGSSGVPS 291 Query: 348 GISDANILGDNFLRSAYLVYDLDDDKISLAQV 379 S+ I GD FLR+ Y +YD ++K+ A Sbjct: 292 NTSELWIFGDVFLRNYYTIYDRTNNKVGFAPA 323 >4Y9W-A nrPDB Length = 334 Score = 309 bits (791), Expect = 2e-84, Method: Composition-based stats. Identities = 173/347 (49%), Positives = 216/347 (62%), Gaps = 20/347 (5%) Query: 51 QAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCK 110 + L E SY +++GSNKQ+ V++DTGSSD WV D+S +C K CK Sbjct: 1 SSPSSPLYFEGPSYGIRVSVGSNKQEQQVVLDTGSSDFWVVDSSASCQKGN-------CK 53 Query: 111 GKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP 170 G + P SST+ ++LG+ F IGYGD SSS GT +DT+ GG SIT Q FAD+T TS+ Sbjct: 54 QYGTFDPHSSTSFKSLGSSFSIGYGDKSSSIGTWGQDTIYLGGTSITNQRFADVTSTSVN 113 Query: 171 QGILGIGYKTNEAA-GDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKY 229 QGILG+G E+A YDNVP+TLK QG I NAYSLYLNSP AATG IIFGGVD AKY Sbjct: 114 QGILGVGRVETESANPPYDNVPITLKKQGKIKTNAYSLYLNSPGAATGTIIFGGVDNAKY 173 Query: 230 SGSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQA 289 SG LI P+ SDR L + L SL G N N V++DSGTTI+YL + D+ + A Sbjct: 174 SGKLIEEPLVSDRYLAVNLKSLNYNGDNSNAGFGVVVDSGTTISYLPDSIVDDLANKVGA 233 Query: 290 ELKSDGQGHTFYVTDCQTS--GTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLL 347 L+ G G+ Y DC + G+ F FDN AKI+VP SEF C L Sbjct: 234 YLEPVGLGNELYFIDCNANPQGSASFTFDNGAKITVPLSEFVLQ------STANACVWGL 287 Query: 348 GISDAN----ILGDNFLRSAYLVYDLDDDKISLAQVKYTSASNIAAL 390 SD ILGDNFLR AY+V++LD + +SLAQVKYTSAS+++A+ Sbjct: 288 QSSDRQNVPPILGDNFLRHAYVVFNLDKETVSLAQVKYTSASSVSAI 334 >5NFG-A nrPDB Length = 383 Score = 308 bits (790), Expect = 2e-84, Method: Composition-based stats. Identities = 86/351 (24%), Positives = 139/351 (39%), Gaps = 31/351 (8%) Query: 47 KVKRQAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSA 106 + I N+ +Y +I IG+ Q F VI DTGSSDLWVP ++ Sbjct: 45 RDSGSGIVALTNDRDTAYYGEIGIGTPPQNFAVIFDTGSSDLWVPSTKC--------DTS 96 Query: 107 DFCKGKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITK 166 C Y S+T + GT I YG G+ G +D+V G + Q F + T+ Sbjct: 97 LACVIHPRYDSGDSSTYKGNGTTASIQYGTGAIV-GFYSQDSVEVGDLVVEHQDFIETTE 155 Query: 167 T-------SIPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNS--PNAATG 217 S GILG+G++ A V + NQG++ + +S +LN G Sbjct: 156 EDDTVFLKSEFDGILGLGFQEISAGKAV-PVWYNMVNQGLVEEAVFSFWLNRNVDEEEGG 214 Query: 218 QIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKN---INGNIDVLLDSGTTITY 274 +++FGGVD + G+ VPVT + + + K+ G + DSGT+ Sbjct: 215 ELVFGGVDPNHFRGNHTYVPVTRKGYWQFEMGDVLIGDKSSGFCAGGCAAIADSGTSFFA 274 Query: 275 LQQDVAQDIIDAFQAELKSDGQGHTFYVTDCQTSGTVD-FNFDNNAK-ISVPASEFTAPL 332 + I A A+ G G + DC ++ F +K V ++ + Sbjct: 275 GPTAIITQINQAIGAKG---GGGSAESIVDCNGISSMPNIAFTIGSKLFEVTPEQYIYKV 331 Query: 333 SYA----NGQPYPKCQLLLGISDANILGDNFLRSAYLVYDLDDDKISLAQV 379 + ++ ILGD F+ + V+D ++ A+ Sbjct: 332 GEGEAATCISGFTALDIMSPQGPIWILGDMFMGPYHTVFDYGKLRVGFAEA 382 >4PEP-A nrPDB Length = 326 Score = 308 bits (788), Expect = 4e-84, Method: Composition-based stats. Identities = 99/333 (29%), Positives = 155/333 (46%), Gaps = 26/333 (7%) Query: 58 NNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTP 117 N Y I IG+ Q F VI DTGSS+LWVP SV C S+ C + P Sbjct: 8 NYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVP--SVYC-------SSLACSDHNQFNP 58 Query: 118 KSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSI-------P 170 S+T + I YG GS + G L DTV GG S T Q+F Sbjct: 59 DDSSTFEATSQELSITYGTGSMT-GILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPF 117 Query: 171 QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYS 230 GILG+ Y + A+G V L +QG+++++ +S+YL+S + + ++ GG+D + Y+ Sbjct: 118 DGILGLAYPSISASGA-TPVFDNLWDQGLVSQDLFSVYLSSNDDSGSVVLLGGIDSSYYT 176 Query: 231 GSLIAVPVTSDRELRITLNSLKAVGKN--INGNIDVLLDSGTTITYLQQDVAQDIIDAFQ 288 GSL VPV+ + +ITL+S+ G+ +G ++D+GT++ +I Sbjct: 177 GSLNWVPVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIG 236 Query: 289 AELKSDGQGHTFYVTDCQTSGT-VDFNFD-NNAKISVPASEFTAPLSYANGQPYPKCQLL 346 A SDG+ V C + + D F + + + S + + + + Sbjct: 237 ASENSDGE----MVISCSSIDSLPDIVFTIDGVQYPLSPSAYILQDDDSCTSGFEGMDVP 292 Query: 347 LGISDANILGDNFLRSAYLVYDLDDDKISLAQV 379 + ILGD F+R Y V+D ++K+ LA V Sbjct: 293 TSSGELWILGDVFIRQYYTVFDRANNKVGLAPV 325 >1SMR-A nrPDB Length = 335 Score = 305 bits (781), Expect = 2e-83, Method: Composition-based stats. Identities = 89/345 (25%), Positives = 154/345 (44%), Gaps = 36/345 (10%) Query: 55 VTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGI 114 V N + Y +I IG+ Q F VI DTGS++LWVP S C + C + Sbjct: 8 VLTNYLNSQYYGEIGIGTPPQTFKVIFDTGSANLWVP--STKCSRLYL-----ACGIHSL 60 Query: 115 YTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSI----- 169 Y S++ G F I YG G +G L +D+V GG ++T Q F ++T+ + Sbjct: 61 YESSDSSSYMENGDDFTIHYGSG-RVKGFLSQDSVTVGGITVT-QTFGEVTQLPLIPFML 118 Query: 170 --PQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNS-PNAATGQIIFGGVDK 226 G+LG+G+ +A G V + +QGV+ + +S+Y N P+ G+++ GG D Sbjct: 119 AQFDGVLGMGFPA-QAVGGVTPVFDHILSQGVLKEKVFSVYYNRGPHLLGGEVVLGGSDP 177 Query: 227 AKYSGSLIAVPVTSDRELRITLNSLKAVGKN--INGNIDVLLDSGTTITYLQQDVAQDII 284 Y G V ++ +IT+ + +V++D+G++ + I+ Sbjct: 178 QHYQGDFHYVSLSKTDSWQITMKGVSVGSSTLLCEEGCEVVVDTGSSFISAPTSSLKLIM 237 Query: 285 DAFQAELKSDGQGHTFYVTDCQTSGT-VDFNFDNNAK-ISVPASEFTAPLSYANGQPYPK 342 A A+ K + YV C T D +F+ + ++ ++++ L Y N + Sbjct: 238 QALGAKEKRLHE----YVVSCSQVPTLPDISFNLGGRAYTLSSTDYV--LQYPNRRD-KL 290 Query: 343 CQLLLGISDA-------NILGDNFLRSAYLVYDLDDDKISLAQVK 380 C + L D +LG F+R Y +D +++I A + Sbjct: 291 CTVALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 335 >2BJU-A nrPDB Length = 453 Score = 304 bits (778), Expect = 5e-83, Method: Composition-based stats. Identities = 94/334 (28%), Positives = 145/334 (43%), Gaps = 32/334 (9%) Query: 60 EHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKS 119 +++ + D +G N+Q F I+DTGS++LWVP SV C C K +Y Sbjct: 136 QNIMFYGDAEVGDNQQPFTFILDTGSANLWVP--SVKCTTAG-------CLTKHLYDSSK 186 Query: 120 STTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQ--------VFADITKTSIPQ 171 S T + GT + Y G+ S G KD V G S+ + F S Sbjct: 187 SRTYEKDGTKVEMNYVSGTVS-GFFSKDLVTVGNLSLPYKFIEVIDTNGFEPTYTASTFD 245 Query: 172 GILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSG 231 GILG+G+K + + G D + V LKNQ I ++ YL + TG + GG+++ Y G Sbjct: 246 GILGLGWK-DLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGFLTIGGIEERFYEG 304 Query: 232 SLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAEL 291 L + D +ITL++ VG + + ++DSGT+ + D ++ Sbjct: 305 PLTYEKLNHDLYWQITLDA--HVGNIMLEKANCIVDSGTSAITVPTDFLNKMLQNLDVIK 362 Query: 292 KSDGQGHTFYVTDCQTSGTVDFNFDN-NAKISVPASEFTAPLSYANGQPYPKCQLLLGIS 350 FYVT C S F F + N K ++ + L + C L + Sbjct: 363 VP---FLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYY---LQHIEDVGPGLCMLNIIGL 416 Query: 351 DA----NILGDNFLRSAYLVYDLDDDKISLAQVK 380 D ILGD F+R + V+D D+ + +A K Sbjct: 417 DFPVPTFILGDPFMRKYFTVFDYDNHSVGIALAK 450 >5N71-A nrPDB Length = 345 Score = 303 bits (775), Expect = 1e-82, Method: Composition-based stats. Identities = 86/353 (24%), Positives = 148/353 (41%), Gaps = 36/353 (10%) Query: 48 VKRQAIPVTLNNE-HVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSA 106 + P L N V Y I+IG+ Q F VI DTGS++LW+P + + Sbjct: 1 IHEGPYPEPLVNLLDVVYYGPISIGTPPQDFQVIFDTGSANLWLPSSKC---------TT 51 Query: 107 DFCKGKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITK 166 +C Y S+T + G F I YG G+ +G + KD G A ++ Q + Sbjct: 52 KYCLHHHRYDSSKSSTYEADGRNFTIVYGSGN-VEGFISKDVCRIGSAKVSGQPLGEALV 110 Query: 167 -------TSIPQGILGIGYKTNEAAGDYDNVPVTLKNQGVI-AKNAYSLYLNSP--NAAT 216 + GILG+ Y + G V + QG++ +N +S+YLN + Sbjct: 111 VGGESLLEAPFDGILGLAYPSIAVDGVV-PVFDNMMKQGLLGEQNVFSVYLNRDPSSKEG 169 Query: 217 GQIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKN-------INGNIDVLLDSG 269 G+++FGG+D Y GS+ VPVT+ + ++ +K+V + + + ++G Sbjct: 170 GEVLFGGIDHDHYKGSITYVPVTAKGYWQFHVDGVKSVSASKSAPELLCKDGCEAIANTG 229 Query: 270 TTITYLQQDVAQDIIDAFQAELKSDGQGHTFYVTDCQTSGTVD-FNFDNNAK-ISVPASE 327 T++ + + GQ Y+ DC ++ F + K S+ + + Sbjct: 230 TSLITGPPEEVDSLNQYLGGTKTEGGQ----YLLDCDKLESLPNVTFTISGKEFSLRSKD 285 Query: 328 FTAPLSYANGQ-PYPKCQLLLGISDANILGDNFLRSAYLVYDLDDDKISLAQV 379 + ++ L ILGD FL Y ++D D D++ A+V Sbjct: 286 YVLKVNQQGQTLCVSGFMGLEMPQPLWILGDVFLGPYYTIFDRDQDRVGFAEV 338 >4AMT-A nrPDB Length = 383 Score = 302 bits (774), Expect = 2e-82, Method: Composition-based stats. Identities = 77/351 (21%), Positives = 151/351 (43%), Gaps = 40/351 (11%) Query: 52 AIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKG 111 + + N Y +I IG+ Q F V+ DTGSS++WVP + + + C Sbjct: 51 SSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCS-------RLYTACVY 103 Query: 112 KGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKT---- 167 ++ S++ ++ GT + Y G+ S G L +D + GG ++T Q+F ++T+ Sbjct: 104 HKLFDASDSSSYKHNGTELTLRYSTGTVS-GFLSQDIITVGGITVT-QMFGEVTEMPALP 161 Query: 168 ---SIPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPN----AATGQII 220 + G++G+G+ +A G + + +QGV+ ++ +S Y N + + GQI+ Sbjct: 162 FMLAEFDGVVGMGF-IEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIV 220 Query: 221 FGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKN--INGNIDVLLDSGTTITYLQQD 278 GG D Y G+ + + +I + + L+D+G + Sbjct: 221 LGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTS 280 Query: 279 VAQDIIDAFQAELKSDGQGHTFYVTDCQTSGT-VDFNFDNNAK-ISVPASEFTAPLSYAN 336 + +++A A+ + YV C T D +F K ++ ++++ SY++ Sbjct: 281 SIEKLMEALGAKKR-----LFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSS 335 Query: 337 GQPYPKCQLLLGISDA-------NILGDNFLRSAYLVYDLDDDKISLAQVK 380 + C L + D LG F+R Y +D +++I A + Sbjct: 336 KK---LCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR 383 >1MIQ-A nrPDB Length = 375 Score = 301 bits (770), Expect = 5e-82, Method: Composition-based stats. Identities = 90/332 (27%), Positives = 144/332 (43%), Gaps = 30/332 (9%) Query: 61 HVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSS 120 ++ + + +G N QKF +I DTGS++LWVP ++ C K +Y S Sbjct: 61 NIMFYGEGEVGDNHQKFMLIFDTGSANLWVPSKKC---------NSSGCSIKNLYDSSKS 111 Query: 121 TTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTS---------IPQ 171 + + GT I YG G+ +G KD V G S+ + F ++T T Sbjct: 112 KSYEKDGTKVDITYGSGT-VKGFFSKDLVTLGHLSMPYK-FIEVTDTDDLEPIYSSVEFD 169 Query: 172 GILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSG 231 GILG+G+K + + G D + V LKNQ I ++ YL + G + GG+++ Y G Sbjct: 170 GILGLGWK-DLSIGSIDPIVVELKNQNKIDNALFTFYLPVHDVHAGYLTIGGIEEKFYEG 228 Query: 232 SLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAEL 291 ++ + D +I L+ GK +V++DSGTT + ++ F A L Sbjct: 229 NITYEKLNHDLYWQIDLDV--HFGKQTMEKANVIVDSGTTTITAPSE----FLNKFFANL 282 Query: 292 KSDGQGHT-FYVTDCQTSGTVDFNF-DNNAKISVPASEFTAPLSYANGQPYPKCQLLLGI 349 FYVT C F N ++ + P+ + L + I Sbjct: 283 NVIKVPFLPFYVTTCDNKEMPTLEFKSANNTYTLEPEYYMNPILEVDDTLCMITMLPVDI 342 Query: 350 -SDANILGDNFLRSAYLVYDLDDDKISLAQVK 380 S+ ILGD F+R + V+D D + + A K Sbjct: 343 DSNTFILGDPFMRKYFTVFDYDKESVGFAIAK 374 >4CMS-A nrPDB Length = 323 Score = 301 bits (770), Expect = 5e-82, Method: Composition-based stats. Identities = 95/339 (28%), Positives = 150/339 (44%), Gaps = 32/339 (9%) Query: 52 AIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKG 111 ++P+T N Y I +G+ Q+F V+ DTGSSD WVP S+ C ++ CK Sbjct: 5 SVPLT-NYLDSQYFGKIYLGTPPQEFTVLFDTGSSDFWVP--SIYC-------KSNACKN 54 Query: 112 KGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGAS-------ITKQVFADI 164 + P+ S+T QNLG P I YG GS QG L DTV ++ Q D+ Sbjct: 55 HQRFDPRKSSTFQNLGKPLSIHYGTGSM-QGILGYDTVTVSNIVDIQQTVGLSTQEPGDV 113 Query: 165 TKTSIPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGV 224 + GILG+ Y + + V + N+ ++A++ +S+Y++ N + G + Sbjct: 114 FTYAEFDGILGMAYPSLASEYSI-PVFDNMMNRHLVAQDLFSVYMDR-NGQESMLTLGAI 171 Query: 225 DKAKYSGSLIAVPVTSDRELRITLNSLKAVG--KNINGNIDVLLDSGTTITYLQQDVAQD 282 D + Y+GSL VPVT + + T++S+ G G +LD+GT+ + Sbjct: 172 DPSYYTGSLHWVPVTVQQYWQFTVDSVTISGVVVACEGGCQAILDTGTSKLVGPSSDILN 231 Query: 283 IIDAFQAELKSDGQGHTFYVTDCQTSG-TVDFNFDNNAK-ISVPASEFTAPLSYANGQPY 340 I A A G+ DC F+ N K + S +T+ + Sbjct: 232 IQQAIGATQNQYGEFD----IDCDNLSYMPTVVFEINGKMYPLTPSAYTSQDQGFCTSGF 287 Query: 341 PKCQLLLGISDANILGDNFLRSAYLVYDLDDDKISLAQV 379 S ILGD F+R Y V+D ++ + LA+ Sbjct: 288 QS----ENHSQKWILGDVFIREYYSVFDRANNLVGLAKA 322 >5BWY-A nrPDB Length = 376 Score = 300 bits (768), Expect = 6e-82, Method: Composition-based stats. Identities = 94/334 (28%), Positives = 145/334 (43%), Gaps = 32/334 (9%) Query: 60 EHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKS 119 +++ + D +G N+Q F I+DTGS++LWVP SV C C K +Y Sbjct: 59 QNIMFYGDAEVGDNQQPFTFILDTGSANLWVP--SVKCTTAG-------CLTKHLYDSSK 109 Query: 120 STTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQ--------VFADITKTSIPQ 171 S T + GT + Y G+ S G KD V G S+ + F S Sbjct: 110 SRTYEKDGTKVEMNYVSGTVS-GFFSKDLVTVGNLSLPYKFIEVIDTNGFEPTYTASTFD 168 Query: 172 GILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSG 231 GILG+G+K + + G D + V LKNQ I ++ YL + TG + GG+++ Y G Sbjct: 169 GILGLGWK-DLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGFLTIGGIEERFYEG 227 Query: 232 SLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAEL 291 L + D +ITL++ VG + + ++DSGT+ + D ++ Sbjct: 228 PLTYEKLNHDLYWQITLDA--HVGNIMLEKANCIVDSGTSAITVPTDFLNKMLQNLDVIK 285 Query: 292 KSDGQGHTFYVTDCQTSGTVDFNFDN-NAKISVPASEFTAPLSYANGQPYPKCQLLLGIS 350 FYVT C S F F + N K ++ + L + C L + Sbjct: 286 VP---FLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYY---LQHIEDVGPGLCMLNIIGL 339 Query: 351 DA----NILGDNFLRSAYLVYDLDDDKISLAQVK 380 D ILGD F+R + V+D D+ + +A K Sbjct: 340 DFPVPTFILGDPFMRKYFTVFDYDNHSVGIALAK 373 >2ANL-A nrPDB Length = 327 Score = 298 bits (762), Expect = 3e-81, Method: Composition-based stats. Identities = 87/334 (26%), Positives = 140/334 (41%), Gaps = 34/334 (10%) Query: 61 HVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSS 120 ++ + + +G N QKF +I DTGS++LWVP ++ C K +Y S Sbjct: 13 NLMFYGEGEVGDNHQKFMLIFDTGSANLWVPSKKC---------NSIGCSTKHLYDSSKS 63 Query: 121 TTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKT---------SIPQ 171 + + GT I YG G+ +G KD V G S+ + F ++T T + Sbjct: 64 KSYEKDGTKVEITYGSGT-VRGFFSKDLVTLGYLSLPYK-FIEVTDTDDLEPLYTAAEFD 121 Query: 172 GILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSG 231 GILG+G+K + + G D + V LKNQ I + ++ YL + +G + GG+++ Y G Sbjct: 122 GILGLGWK-DLSIGSIDPIVVELKNQNKIDQALFTFYLPVHDKHSGYLTIGGIEEKFYEG 180 Query: 232 SLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAEL 291 L + D ++ L+ GK +V++DSGT+ Sbjct: 181 ELTYEKLNHDLFWQVDLDVN--FGKTSMEKANVIVDSGTSTITAPTSFINKFFKDLNVIK 238 Query: 292 KSDGQGHTFYVTDCQTSGTVDFNF-DNNAKISVPASEFTAPLSYANGQPYPKCQLLLGIS 350 FY+T C F N ++ + PL + C L + Sbjct: 239 VP---FLPFYITTCNNKDMPTLEFKSANNTYTLEPEYYMEPLLDIDDT---LCMLYILPV 292 Query: 351 DAN----ILGDNFLRSAYLVYDLDDDKISLAQVK 380 D + ILGD F+R + V+D D + I A K Sbjct: 293 DIDKNTFILGDPFMRKYFTVFDYDKESIGFAVAK 326 >1XDH-A nrPDB Length = 331 Score = 297 bits (760), Expect = 6e-81, Method: Composition-based stats. Identities = 91/334 (27%), Positives = 143/334 (42%), Gaps = 32/334 (9%) Query: 60 EHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKS 119 +++ + D +G N+Q F I+DTGS++LWVP + C K +Y Sbjct: 14 QNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKC---------TTAGCLTKHLYDSSK 64 Query: 120 STTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQ--------VFADITKTSIPQ 171 S T + GT + Y G+ S G KD V G S+ + F S Sbjct: 65 SRTYEKDGTKVEMNYVSGTVS-GFFSKDLVTVGNLSLPYKFIEVIDTNGFEPTYTASTFD 123 Query: 172 GILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSG 231 GILG+G+K + + G D + V LKNQ I ++ YL + TG + GG+++ Y G Sbjct: 124 GILGLGWK-DLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHTGFLTIGGIEERFYEG 182 Query: 232 SLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAEL 291 L + D +ITL++ VG + + ++DSGT+ + D ++ Sbjct: 183 PLTYEKLNHDLYWQITLDA--HVGNIMLEKANCIVDSGTSAITVPTDFLNKMLQNLDVIK 240 Query: 292 KSDGQGHTFYVTDCQTSGTVDFNFDN-NAKISVPASEFTAPLSYANGQPYPKCQLLLGIS 350 FYVT C S F F + N K ++ + L + C L + Sbjct: 241 VP---FLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYY---LQHIEDVGPGLCMLNIIGL 294 Query: 351 DA----NILGDNFLRSAYLVYDLDDDKISLAQVK 380 D ILGD F+R + V+D D+ + +A K Sbjct: 295 DFPVPTFILGDPFMRKYFTVFDYDNHSVGIALAK 328 >1QS8-A nrPDB Length = 329 Score = 297 bits (760), Expect = 6e-81, Method: Composition-based stats. Identities = 88/331 (26%), Positives = 140/331 (42%), Gaps = 28/331 (8%) Query: 61 HVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSS 120 ++ + + +G N QKF +I DTGS++LWVP ++ C K +Y S Sbjct: 15 NIMFYGEGEVGDNHQKFMLIFDTGSANLWVPSKKC---------NSSGCSIKNLYDSSKS 65 Query: 121 TTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTS--------IPQG 172 + + GT I YG G+ +G KD V G S+ + I G Sbjct: 66 KSYEKDGTKVDITYGSGT-VKGFFSKDLVTLGHLSMPYKFIEVIDTDDLEPIYSSVEFDG 124 Query: 173 ILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSGS 232 ILG+G+K + + G D + V LKNQ I ++ YL + G + GG+++ Y G+ Sbjct: 125 ILGLGWK-DLSIGSIDPIVVELKNQNKIDNALFTFYLPVHDVHAGYLTIGGIEEKFYEGN 183 Query: 233 LIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAELK 292 + + D +I L+ GK +V++DSGTT + ++ F A L Sbjct: 184 ITYEKLNHDLYWQIDLDV--HFGKQTMEKANVIVDSGTTTITAPSE----FLNKFFANLN 237 Query: 293 SDGQGHT-FYVTDCQTSGTVDFNF-DNNAKISVPASEFTAPLSYANGQPYPKCQLLLGI- 349 FYVT C F N ++ + P+ + L + I Sbjct: 238 VIKVPFLPFYVTTCDNKEMPTLEFKSANNTYTLEPEYYMNPILEVDDTLCMITMLPVDID 297 Query: 350 SDANILGDNFLRSAYLVYDLDDDKISLAQVK 380 S+ ILGD F+R + V+D D + + A K Sbjct: 298 SNTFILGDPFMRKYFTVFDYDKESVGFAIAK 328 >3VCM-A nrPDB Length = 335 Score = 296 bits (759), Expect = 7e-81, Method: Composition-based stats. Identities = 77/347 (22%), Positives = 151/347 (43%), Gaps = 37/347 (10%) Query: 52 AIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKG 111 + + N Y +I IG+ Q F V+ DTGSS++WVP + + + C Sbjct: 8 SSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCS-------RLYTACVY 60 Query: 112 KGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKT---- 167 ++ S++ ++ GT + Y G+ S G L +D + GG ++T Q+F ++T+ Sbjct: 61 HKLFDASDSSSYKHNGTELTLRYSTGTVS-GFLSQDIITVGGITVT-QMFGEVTEMPALP 118 Query: 168 ---SIPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGV 224 + G++G+G+ +A G + + +QGV+ ++ +S Y N ++ GQI+ GG Sbjct: 119 FMLAEFDGVVGMGF-IEQAIGRVTPIFDNIISQGVLKEDVFSFYYNR-DSLGGQIVLGGS 176 Query: 225 DKAKYSGSLIAVPVTSDRELRITLNSLKAVGKN--INGNIDVLLDSGTTITYLQQDVAQD 282 D Y G+ + + +I + + L+D+G + + Sbjct: 177 DPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEK 236 Query: 283 IIDAFQAELKSDGQGHTFYVTDCQTSGT-VDFNFDNNAK-ISVPASEFTAPLSYANGQPY 340 +++A A+ + YV C T D +F K ++ ++++ SY++ + Sbjct: 237 LMEALGAKKR-----LFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKK-- 289 Query: 341 PKCQLLLGISDA-------NILGDNFLRSAYLVYDLDDDKISLAQVK 380 C L + D LG F+R Y +D +++I A + Sbjct: 290 -LCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR 335 >5JOD-A nrPDB Length = 375 Score = 293 bits (751), Expect = 6e-80, Method: Composition-based stats. Identities = 90/356 (25%), Positives = 148/356 (41%), Gaps = 35/356 (9%) Query: 40 NATGQEGKVKRQAIPVTLNN-EHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCD 98 + Q+G + + + L++ ++ + + IG+NKQ F I DTGS++LWVP + Sbjct: 38 SGYAQKGYLGSENDSIELDDVANLMFYGEGQIGTNKQPFMFIFDTGSANLWVPSVNC--- 94 Query: 99 KPRPGQSADFCKGKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITK 158 + C K +Y +S + + GT I YG G+ +G KD + G S+ Sbjct: 95 ------DSIGCSTKHLYDASASKSYEKDGTKVEISYGSGT-VRGYFSKDVISLGDLSLPY 147 Query: 159 QVFADITKT---------SIPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYL 209 + F ++T S GILG+G+K + + G D V V LK Q I ++ YL Sbjct: 148 K-FIEVTDADDLEPIYSGSEFDGILGLGWK-DLSIGSIDPVVVELKKQNKIDNALFTFYL 205 Query: 210 NSPNAATGQIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSG 269 + G + GG++ Y G L + D +I L+ GK + + ++DSG Sbjct: 206 PVHDKHVGYLTIGGIESDFYEGPLTYEKLNHDLYWQIDLDI--HFGKYVMQKANAVVDSG 263 Query: 270 TTITYLQQDVAQDIIDAFQAELKSDGQGHTFYVTDCQTSGTVDFNFDN-NAKISVPASEF 328 T+ YVT C F + N K ++ + Sbjct: 264 TSTITAPTSFLNKFFRDMNVIKVP---FLPLYVTTCDNDDLPTLEFHSRNNKYTLEPEFY 320 Query: 329 TAPLSYANGQPYPKCQLLLGISDAN----ILGDNFLRSAYLVYDLDDDKISLAQVK 380 PLS + C L + D + ILGD F+R + V+D + + + A K Sbjct: 321 MDPLSDID---PALCMLYILPVDIDDNTFILGDPFMRKYFTVFDYEKESVGFAVAK 373 >5I70-B nrPDB Length = 328 Score = 293 bits (750), Expect = 9e-80, Method: Composition-based stats. Identities = 87/334 (26%), Positives = 138/334 (41%), Gaps = 34/334 (10%) Query: 61 HVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSS 120 ++ + + IG+NKQ F I DTGS++LWVP + + C K +Y +S Sbjct: 13 NLMFYGEGQIGTNKQPFMFIFDTGSANLWVPSVNC---------DSIGCSTKHLYDASAS 63 Query: 121 TTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKT---------SIPQ 171 + + GT I YG G+ +G KD + G S+ + F ++T S Sbjct: 64 KSYEKDGTKVEISYGSGT-VRGYFSKDVISLGDLSLPYK-FIEVTDADDLEPIYSGSEFD 121 Query: 172 GILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSG 231 GILG+G+K + + G D V V LK Q I ++ YL + G + GG++ Y G Sbjct: 122 GILGLGWK-DLSIGSIDPVVVELKKQNKIDNALFTFYLPVHDKHVGYLTIGGIESDFYEG 180 Query: 232 SLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAEL 291 L + D +I L+ GK + + ++DSGT+ Sbjct: 181 PLTYEKLNHDLYWQIDLDI--HFGKYVMQKANAVVDSGTSTITAPTSFLNKFFRDMNVIK 238 Query: 292 KSDGQGHTFYVTDCQTSGTVDFNFDN-NAKISVPASEFTAPLSYANGQPYPKCQLLLGIS 350 YVT C F + N K ++ + PLS + C L + Sbjct: 239 VP---FLPLYVTTCDNDDLPTLEFHSRNNKYTLEPEFYMDPLSDID---PALCMLYILPV 292 Query: 351 DAN----ILGDNFLRSAYLVYDLDDDKISLAQVK 380 D + ILGD F+R + V+D + + + A K Sbjct: 293 DIDDNTFILGDPFMRKYFTVFDYEKESVGFAVAK 326 >1FMX-A nrPDB Length = 329 Score = 291 bits (744), Expect = 5e-79, Method: Composition-based stats. Identities = 92/344 (26%), Positives = 150/344 (43%), Gaps = 31/344 (9%) Query: 50 RQAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFC 109 +P+T N + Y DIT+G+ Q F VI+DTGSS+LWVP + C Sbjct: 2 GHDVPLT-NYLNAQYYTDITLGTPPQNFKVILDTGSSNLWVPSNEC---------GSLAC 51 Query: 110 KGKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSI 169 Y ++S++ + GT F I YG GS +G + +DT+ G +I KQ FA+ T Sbjct: 52 FLHSKYDHEASSSYKANGTEFAIQYGTGSL-EGYISQDTLSIGDLTIPKQDFAEATSEPG 110 Query: 170 -------PQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYL---NSPNAATGQI 219 GILG+GY T Q ++ + ++ YL + G+ Sbjct: 111 LTFAFGKFDGILGLGYDTISVDKVVPP-FYNAIQQDLLDEKRFAFYLGDTSKDTENGGEA 169 Query: 220 IFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNIN-GNIDVLLDSGTTITYLQQD 278 FGG+D++K+ G + +PV + + + + +D+GT++ L Sbjct: 170 TFGGIDESKFKGDITWLPVRRKAYWEVKFEGIGLGDEYAELESHGAAIDTGTSLITLPSG 229 Query: 279 VAQDIIDAFQAELKSDGQGHTFYVTDCQTSGTVD---FNFDNNAKISVPASEFTAPLSYA 335 +A+ I A+ GQ Y DC T + FNF N ++ ++T +S + Sbjct: 230 LAEMINAEIGAKKGWTGQ----YTLDCNTRDNLPDLIFNF-NGYNFTIGPYDYTLEVSGS 284 Query: 336 NGQPYPKCQLLLGISDANILGDNFLRSAYLVYDLDDDKISLAQV 379 + I+GD FLR Y +YDL ++ + LA+ Sbjct: 285 CISAITPMDFPEPVGPLAIVGDAFLRKYYSIYDLGNNAVGLAKA 328 >3QS1-A nrPDB Length = 336 Score = 290 bits (741), Expect = 9e-79, Method: Composition-based stats. Identities = 90/342 (26%), Positives = 137/342 (40%), Gaps = 35/342 (10%) Query: 54 PVTLNN-EHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGK 112 VTLN+ +V Y + IG NKQKF I DTGS++LWVP A + CK K Sbjct: 12 SVTLNDVANVMYYGEAQIGDNKQKFAFIFDTGSANLWVPSAQC---------NTIGCKTK 62 Query: 113 GIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP-- 170 +Y S T + GT + Y G+ S G KD V S + F ++T T+ Sbjct: 63 NLYDSNKSKTYEKDGTKVEMNYVSGTVS-GFFSKDIVTIANLSFPYK-FIEVTDTNGFEP 120 Query: 171 -------QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGG 223 GI+G+G+K + + G D V V LKNQ I + ++ YL + G + GG Sbjct: 121 AYTLGQFDGIVGLGWK-DLSIGSVDPVVVELKNQNKIEQAVFTFYLPFDDKHKGYLTIGG 179 Query: 224 VDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDI 283 ++ Y G L + D ++ L+ G ++DSGT+ + Sbjct: 180 IEDRFYEGQLTYEKLNHDLYWQVDLD--LHFGNLTVEKATAIVDSGTSSITAPTEFLNKF 237 Query: 284 IDAFQAELKSDGQGHTFYVTDCQTSGTVDFNFDNNAK-ISVPASEFTAPLSYANGQPYPK 342 + Y+T C F + ++ + L Sbjct: 238 FEGLDVVKIP---FLPLYITTCNNPKLPTLEFRSATNVYTLEPEYY---LQQIFDFGISL 291 Query: 343 CQLLLGISDAN----ILGDNFLRSAYLVYDLDDDKISLAQVK 380 C + + D N ILGD F+R + V+D D+ + A K Sbjct: 292 CMVSIIPVDLNKNTFILGDPFMRKYFTVFDYDNHTVGFALAK 333 >1AVF-A nrPDB Length = 329 Score = 289 bits (739), Expect = 2e-78, Method: Composition-based stats. Identities = 84/335 (25%), Positives = 139/335 (41%), Gaps = 29/335 (8%) Query: 59 NEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPK 118 +Y +I+IG+ Q F V+ DTGSS+LWVP SV C + C + P Sbjct: 9 YMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVP--SVYCQ-------SQACTSHSRFNPS 59 Query: 119 SSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSI-------PQ 171 S+T G F + YG GS + G DT+ + Q F Sbjct: 60 ESSTYSTNGQTFSLQYGSGSLT-GFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFD 118 Query: 172 GILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYL-NSPNAATGQIIFGGVDKAKYS 230 GI+G+ Y + + + +G + +S+YL N ++ G ++FGGVD + Y+ Sbjct: 119 GIMGLAYPA-LSVDEATTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGVDSSLYT 177 Query: 231 GSLIAVPVTSDRELRITLNSLKAVGKN---INGNIDVLLDSGTTITYLQQDVAQDIIDAF 287 G + PVT + +I + G+ + ++D+GT++ + Q ++ A Sbjct: 178 GQIYWAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQAT 237 Query: 288 QAELKSDGQGHTFYVTDCQTS-GTVDFNF-DNNAKISVPASEFTAPLSYANGQPYPKCQL 345 A+ GQ ++ +C + F N + +P S + + L Sbjct: 238 GAQEDEYGQ----FLVNCNSIQNLPSLTFIINGVEFPLPPSSYILSNNGYCTVGVEPTYL 293 Query: 346 LLGIS-DANILGDNFLRSAYLVYDLDDDKISLAQV 379 ILGD FLRS Y VYDL ++++ A Sbjct: 294 SSQNGQPLWILGDVFLRSYYSVYDLGNNRVGFATA 328 >3QVI-A nrPDB Length = 451 Score = 273 bits (699), Expect = 7e-74, Method: Composition-based stats. Identities = 79/329 (24%), Positives = 133/329 (40%), Gaps = 32/329 (9%) Query: 65 AADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTTSQ 124 + +G N QKFN + T SS++WVP +++ C+ K Y S T + Sbjct: 140 FGEAKLGDNGQKFNFLFHTASSNVWVPSIKC---------TSESCESKNHYDSSKSKTYE 190 Query: 125 NLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQ--------VFADITKTSIPQGILGI 176 TP + G+ S G KD V G S+ + F S G+ G+ Sbjct: 191 KDDTPVKLTSKAGTIS-GIFSKDLVTIGKLSVPYKFIEMTEIVGFEPFYSESDVDGVFGL 249 Query: 177 GYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSGSLIAV 236 G+K + + G D V LK Q I + YS+YL N G + GG+++ + G L Sbjct: 250 GWK-DLSIGSIDPYIVELKTQNKIEQAVYSIYLPPENKNKGYLTIGGIEERFFDGPLNYE 308 Query: 237 PVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAELKSDGQ 296 + D ++ L+ G + +V+LDS T++ + + +++ Sbjct: 309 KLNHDLMWQVDLDV--HFGNVSSKKANVILDSATSVITVPTEFFNQFVESASVFKVP--- 363 Query: 297 GHTFYVTDCQTSGTVDFNFDNNAK-ISVPASEFTAPLSYANGQPYPKCQLLLGISDA--- 352 + YVT C + + + K ++ ++ PL C L + D Sbjct: 364 FLSLYVTTCGNTKLPTLEYRSPNKVYTLEPKQYLEPLENIFSA---LCMLNIVPIDLEKN 420 Query: 353 -NILGDNFLRSAYLVYDLDDDKISLAQVK 380 +LGD F+R + VYD D+ + A K Sbjct: 421 TFVLGDPFMRKYFTVYDYDNHTVGFALAK 449 >3FNT-A nrPDB Length = 332 Score = 268 bits (686), Expect = 3e-72, Method: Composition-based stats. Identities = 79/329 (24%), Positives = 133/329 (40%), Gaps = 32/329 (9%) Query: 65 AADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTTSQ 124 + +G N QKFN + T SS++WVP +++ C+ K Y S T + Sbjct: 21 FGEAKLGDNGQKFNFLFHTASSNVWVPSIKC---------TSESCESKNHYDSSKSKTYE 71 Query: 125 NLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQ--------VFADITKTSIPQGILGI 176 TP + G+ S G KD V G S+ + F S G+ G+ Sbjct: 72 KDDTPVKLTSKAGTIS-GIFSKDLVTIGKLSVPYKFIEMTEIVGFEPFYSESDVDGVFGL 130 Query: 177 GYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSGSLIAV 236 G+K + + G D V LK Q I + YS+YL N G + GG+++ + G L Sbjct: 131 GWK-DLSIGSIDPYIVELKTQNKIEQAVYSIYLPPENKNKGYLTIGGIEERFFDGPLNYE 189 Query: 237 PVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAELKSDGQ 296 + D ++ L+ G + +V+LDS T++ + + +++ Sbjct: 190 KLNHDLMWQVDLDV--HFGNVSSKKANVILDSATSVITVPTEFFNQFVESASVFKVP--- 244 Query: 297 GHTFYVTDCQTSGTVDFNFDNNAK-ISVPASEFTAPLSYANGQPYPKCQLLLGISDA--- 352 + YVT C + + + K ++ ++ PL C L + D Sbjct: 245 FLSLYVTTCGNTKLPTLEYRSPNKVYTLEPKQYLEPLENIFSA---LCMLNIVPIDLEKN 301 Query: 353 -NILGDNFLRSAYLVYDLDDDKISLAQVK 380 +LGD F+R + VYD D+ + A K Sbjct: 302 TFVLGDPFMRKYFTVYDYDNHTVGFALAK 330 >1UH8-A nrPDB Length = 325 Score = 258 bits (659), Expect = 3e-69, Method: Composition-based stats. Identities = 104/339 (30%), Positives = 155/339 (45%), Gaps = 29/339 (8%) Query: 51 QAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCK 110 +P+T + Y +TIG+ +KFN+ DTGSSDLW+ AS C Q+ Sbjct: 4 GTVPMTDYGNDIEYYGQVTIGTPGKKFNLDFDTGSSDLWI--ASTLCTNCGSRQTK---- 57 Query: 111 GKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSI- 169 Y P S+T Q G + I YGDGSS+ G L KD V GG I Q + + Sbjct: 58 ----YDPNQSSTYQADGRTWSISYGDGSSASGILAKDNVNLGGLLIKGQTIELAKREAAS 113 Query: 170 -----PQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYL-NSPNAATGQIIFGG 223 G+LG+G+ T L +QG+I++ + +YL + N G+ IFGG Sbjct: 114 FASGPNDGLLGLGFDTITTVRGVKTPMDNLISQGLISRPIFGVYLGKAKNGGGGEYIFGG 173 Query: 224 VDKAKYSGSLIAVPVTSDRELR-ITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQD 282 D K+ GSL VP+ + R IT++ + + D +LD+GTT+ L ++A Sbjct: 174 YDSTKFKGSLTTVPIDNSRGWWGITVDRATVGTSTVASSFDGILDTGTTLLILPNNIAAS 233 Query: 283 IIDAFQAELKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPK 342 + A+ A DG Y C TS F N AS +P S + + Sbjct: 234 VARAYGASDNGDGT----YTISCDTSRFKPLVFSING-----ASFQVSPDSLVFEEFQGQ 284 Query: 343 CQLLLGIS--DANILGDNFLRSAYLVYDLDDDKISLAQV 379 C G D I+GD FL++ Y+V++ ++ +A V Sbjct: 285 CIAGFGYGNWDFAIIGDTFLKNNYVVFNQGVPEVQIAPV 323 >1QDM-A nrPDB Length = 478 Score = 252 bits (643), Expect = 2e-67, Method: Composition-based stats. Identities = 74/260 (28%), Positives = 111/260 (42%), Gaps = 22/260 (8%) Query: 49 KRQAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADF 108 + I N + Y +I +G+ QKF VI DTGSS+LWVP A + Sbjct: 39 EEGDIVALKNYMNAQYFGEIGVGTPPQKFTVIFDTGSSNLWVPSAKCY--------FSIA 90 Query: 109 CKGKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTS 168 C Y +S+T + G P I YG GS + G +D+V G + Q F + TK Sbjct: 91 CYLHSRYKAGASSTYKKNGKPAAIQYGTGSIA-GYFSEDSVTVGDLVVKDQEFIEATKEP 149 Query: 169 I-------PQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSP--NAATGQI 219 GILG+G+K + G V + QG+++ +S +LN G+I Sbjct: 150 GITFLVAKFDGILGLGFKEI-SVGKAVPVWYKMIEQGLVSDPVFSFWLNRHVDEGEGGEI 208 Query: 220 IFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKN---INGNIDVLLDSGTTITYLQ 276 IFGG+D Y G VPVT + + + GK+ G + DSGT++ Sbjct: 209 IFGGMDPKHYVGEHTYVPVTQKGYWQFDMGDVLVGGKSTGFCAGGCAAIADSGTSLLAGP 268 Query: 277 QDVAQDIIDAFQAELKSDGQ 296 + +I + A + Sbjct: 269 TAIITEINEKIGAAGVVSQE 288 Score = 66.2 bits (160), Expect = 2e-11, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 29/83 (34%), Gaps = 6/83 (7%) Query: 303 TDCQTSGT-VDFNFDNNAK-ISVPASEFTAPLSYA----NGQPYPKCQLLLGISDANILG 356 DC + G+ D F K ++ E+ + + + ILG Sbjct: 395 VDCGSLGSMPDIEFTIGGKKFALKPEEYILKVGEGAAAQCISGFTAMDIPPPRGPLWILG 454 Query: 357 DNFLRSAYLVYDLDDDKISLAQV 379 D F+ + V+D +I A+ Sbjct: 455 DVFMGPYHTVFDYGKLRIGFAKA 477 >2ASI-A nrPDB Length = 361 Score = 241 bits (616), Expect = 3e-64, Method: Composition-based stats. Identities = 91/350 (26%), Positives = 147/350 (42%), Gaps = 49/350 (14%) Query: 63 SYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTT 122 YA ++IG+ Q F ++ DTGSSD WVP T ++ C G + P +S+T Sbjct: 19 EYAIPVSIGTPGQDFLLLFDTGSSDTWVPHKGCT--------KSEGCVGSRFFDPSASST 70 Query: 123 SQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP------------ 170 + I YG G + G ++D++ G ++TKQ+ A + P Sbjct: 71 FKATNYNLNITYGTGG-ANGLYFEDSIAIGDITVTKQILAYVDNVRGPTAEQSPNADIFL 129 Query: 171 QGILGIGYKTNEA-----AGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVD 225 G+ G Y N A Y+ V V L QG+I+ +S+Y+N+ N+ TG+++FGGV+ Sbjct: 130 DGLFGAAYPDNTAMEAEYGSTYNTVHVNLYKQGLISSPLFSVYMNT-NSGTGEVVFGGVN 188 Query: 226 KAKYSGSLIAVPVTSDRELRITLNSLKAVGKNINGNIDV--------LLDSGTTITYLQQ 277 G + V S R G ++G+ V +D+GT + Sbjct: 189 NTLLGGDIAYTDVMS-RYGGYYFWDAPVTGITVDGSAAVRFSRPQAFTIDTGTNFFIMPS 247 Query: 278 DVAQDIIDAFQAELKSDGQGHTFYVTDCQTSGTV-------DFNFDNNAKISVPASEFTA 330 A I+ A + QG Q S + + + +ISVP S+ Sbjct: 248 SAASKIVKAALPDATETQQGWVVPCASYQNSKSTISIVMQKSGSSSDTIEISVPVSKMLL 307 Query: 331 PLSYANGQPYPKCQLLLGISDAN--ILGDNFLRSAYLVYDLDDDKISLAQ 378 P+ +N C ++ N I+G+ FLR VYD +++I A Sbjct: 308 PVDQSN----ETCMFIILPDGGNQYIVGNLFLRFFVNVYDFGNNRIGFAP 353 >1B5F-A nrPDB Length = 239 Score = 240 bits (613), Expect = 7e-64, Method: Composition-based stats. Identities = 69/253 (27%), Positives = 108/253 (42%), Gaps = 26/253 (10%) Query: 50 RQAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFC 109 A+ N+ SY +I IG+ QKF VI DTGSS LWVP + ++ C Sbjct: 1 GSAVVALTNDRDTSYFGEIGIGTPPQKFTVIFDTGSSVLWVPSSKCI--------NSKAC 52 Query: 110 KGKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSI 169 + +Y S+T + GT I YG GS + G +D+V G + +Q F + T + Sbjct: 53 RAHSMYESSDSSTYKENGTFGAIIYGTGSIT-GFFSQDSVTIGDLVVKEQDFIEATDEAD 111 Query: 170 -------PQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNS--PNAATGQII 220 GILG+ ++T V + NQG++ + +S +LN G+++ Sbjct: 112 NVFLHRLFDGILGLSFQTISV-----PVWYNMLNQGLVKERRFSFWLNRNVDEEEGGELV 166 Query: 221 FGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKN---INGNIDVLLDSGTTITYLQQ 277 FGG+D + G VPVT + + + K+ DSGT++ Sbjct: 167 FGGLDPNHFRGDHTYVPVTYQYYWQFGIGDVLIGDKSTGFCAPGCQAFADSGTSLLSGPT 226 Query: 278 DVAQDIIDAFQAE 290 + I A A Sbjct: 227 AIVTQINHAIGAN 239 >1IBQ-A nrPDB Length = 325 Score = 229 bits (583), Expect = 2e-60, Method: Composition-based stats. Identities = 88/340 (25%), Positives = 147/340 (43%), Gaps = 30/340 (8%) Query: 49 KRQAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADF 108 K A+ NN+ Y +T+G K ++ DTGS+DLWV + + P Q+ Sbjct: 2 KGSAVTTPQNNDE-EYLTPVTVG--KSTLHLDFDTGSADLWV----FSDELPSSEQT--- 51 Query: 109 CKGKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFA------ 162 G +YTP SS T + G + I YGDGSS+ G +Y+DTV GG + KQ Sbjct: 52 --GHDLYTPSSSAT-KLSGYSWDISYGDGSSASGDVYRDTVTVGGVTTNKQAVEAASKIS 108 Query: 163 -DITKTSIPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIF 221 + + + G+LG+ + + + + +++ L + A G F Sbjct: 109 SEFVQDTANDGLLGLAFSSINTVQPKAQTTFFDTVKSQLDSPLFAVQLK--HDAPGVYDF 166 Query: 222 GGVDKAKYSGSLIAVPVTSDR-ELRITLN-SLKAVGKNINGNIDVLLDSGTTITYLQQDV 279 G +D +KY+GS+ S + + + G + + + D+GTT+ L ++ Sbjct: 167 GYIDDSKYTGSITYTDADSSQGYWGFSTDGYSIGDGSSSSSGFSAIADTGTTLILLDDEI 226 Query: 280 AQDIIDAFQAELKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFT--APLSYANG 337 + +S G YV C T DF +V ++ AP+S + Sbjct: 227 VSAYYEQVSGAQESYEAGG--YVFSCST-DLPDFTVVIGDYKAVVPGKYINYAPVSTGSS 283 Query: 338 QPYPKCQLLLGISDANILGDNFLRSAYLVYDLDDDKISLA 377 Y Q G+ +ILGD FL+S Y+V++ + K+ A Sbjct: 284 TCYGGIQSNSGLG-LSILGDVFLKSQYVVFNSEGPKLGFA 322 >1IZE-A nrPDB Length = 323 Score = 224 bits (572), Expect = 4e-59, Method: Composition-based stats. Identities = 78/335 (23%), Positives = 135/335 (40%), Gaps = 26/335 (7%) Query: 51 QAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCK 110 ++ + Y +T+G + + DTGS+DLWV + + Sbjct: 4 GSVTTNPTSNDEEYITQVTVGDD--TLGLDFDTGSADLWVFSSQTPSSER---------S 52 Query: 111 GKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFA-------D 163 G YTP S+ + G + I YGDGSS+ G +YKD V GG S Q + Sbjct: 53 GHDYYTPG-SSAQKIDGATWSISYGDGSSASGDVYKDKVTVGGVSYDSQAVESAEKVSSE 111 Query: 164 ITKTSIPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGG 223 T+ + G+LG+ + + + +++ +++ L + A G FG Sbjct: 112 FTQDTANDGLLGLAFSSINTVQPTPQKTFFDNVKSSLSEPIFAVALK--HNAPGVYDFGY 169 Query: 224 VDKAKYSGSLIAVPVTSDRELR-ITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQD 282 D +KY+GS+ V + + T + + + +I + D+GTT+ L + Sbjct: 170 TDSSKYTGSITYTDVDNSQGFWGFTADGYSIGSDSSSDSITGIADTGTTLLLLDDSIVDA 229 Query: 283 IIDAFQAELKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPK 342 + QG YV ++ DF+ + E+ + NGQ + Sbjct: 230 YYEQVNGASYDSSQGG--YVFP-SSASLPDFSVTIGDYTATVPGEYISFADVGNGQTFGG 286 Query: 343 CQLLLGISDANILGDNFLRSAYLVYDLDDDKISLA 377 Q GI +I GD FL+S Y+V+D ++ A Sbjct: 287 IQSNSGIG-FSIFGDVFLKSQYVVFDASGPRLGFA 320 >1MPP-A nrPDB Length = 361 Score = 223 bits (568), Expect = 1e-58, Method: Composition-based stats. Identities = 89/355 (25%), Positives = 145/355 (40%), Gaps = 59/355 (16%) Query: 63 SYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTT 122 YA ++IG+ Q F ++ DTGSSD WVP +++ C GK + P SS+T Sbjct: 19 EYAIPVSIGTPGQDFYLLFDTGSSDTWVPHKGC--------DNSEGCVGKRFFDPSSSST 70 Query: 123 SQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP------------ 170 + I YG G + G ++D++ GGA++ +Q A + S P Sbjct: 71 FKETDYNLNITYGTGG-ANGIYFRDSITVGGATVKQQTLAYVDNVSGPTAEQSPDSELFL 129 Query: 171 QGILGIGYKTNEAAGD-----YDNVPVTLKNQGVIAKNAYSLYLNSPNAA---------- 215 GI G Y N A Y+ V V L QG+I+ +S+Y+N+ + Sbjct: 130 DGIFGAAYPDNTAMEAEYGDTYNTVHVNLYKQGLISSPVFSVYMNTNDGGGQVVFGGVNN 189 Query: 216 ---TGQIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTI 272 G I + V K++ PVT + ++ AV + +G +D+GT Sbjct: 190 TLLGGDIQYTDVLKSRGGYFFWDAPVTG-----VKIDGSDAV--SFDGAQAFTIDTGTNF 242 Query: 273 TYLQQDVAQDIIDAFQAELKSDGQGHTFYVTDCQTSGTV-------DFNFDNNAKISVPA 325 A+ ++ A + QG+T + Q S T + + +SVP Sbjct: 243 FIAPSSFAEKVVKAALPDATESQQGYTVPCSKYQDSKTTFSLVLQKSGSSSDTIDVSVPI 302 Query: 326 SEFTAPLSYANGQPYPKCQLLLGISDAN--ILGDNFLRSAYLVYDLDDDKISLAQ 378 S+ P+ + C ++ N I+G+ FLR VYD ++I A Sbjct: 303 SKMLLPVDKSG----ETCMFIVLPDGGNQFIVGNLFLRFFVNVYDFGKNRIGFAP 353 >3TPL-A nrPDB Length = 433 Score = 221 bits (564), Expect = 3e-58, Method: Composition-based stats. Identities = 80/376 (21%), Positives = 150/376 (39%), Gaps = 63/376 (16%) Query: 49 KRQAIPVTLNNEHVS---YAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQS 105 + + + N S Y ++T+GS Q N++VDTGSS+ V A P P Sbjct: 36 RGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAA------PHPFL- 88 Query: 106 ADFCKGKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGF-GGASITKQV-FAD 163 Y + S+T ++L Y+ Y G+ + G L D V G ++T + A Sbjct: 89 ------HRYYQRQLSSTYRDLRKGVYVPYTQGAWA-GELGTDLVSIPHGPNVTVRANIAA 141 Query: 164 ITKT-------SIPQGILGIGYKTNE-AAGDYDNVPVTLKNQGVIAKNAYSLYLNSPN-- 213 IT++ S +GILG+ Y + +L Q N +SL L Sbjct: 142 ITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQ-THVPNLFSLQLCGAGFP 200 Query: 214 --------AATGQIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNINGNI--- 262 + G +I GG+D + Y+GSL P+ + + + ++ G+++ + Sbjct: 201 LNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEY 260 Query: 263 ---DVLLDSGTTITYLQQDVAQDIIDAFQAELKSDGQGHTFYVTD---CQTSGTVDFNF- 315 ++DSGTT L + V + + + +A ++ F++ + C +GT +N Sbjct: 261 NYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIF 320 Query: 316 ------------DNNAKISVPASEFTAPLSYANGQPYPKCQ--LLLGISDANILGDNFLR 361 + + +I++ ++ P+ C + S ++G + Sbjct: 321 PVISLYLMGEVTNQSFRITILPQQYLRPVEDV-ATSQDDCYKFAISQSSTGTVMGAVIME 379 Query: 362 SAYLVYDLDDDKISLA 377 Y+V+D +I A Sbjct: 380 GFYVVFDRARKRIGFA 395 >1PPK-E nrPDB Length = 323 Score = 221 bits (564), Expect = 3e-58, Method: Composition-based stats. Identities = 85/332 (25%), Positives = 137/332 (41%), Gaps = 28/332 (8%) Query: 56 TLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIY 115 T Y +TIG N+ DTGS+DLWV + + P QS G +Y Sbjct: 9 TPTANDEEYITPVTIG--GTTLNLNFDTGSADLWV----FSTELPASQQS-----GHSVY 57 Query: 116 TPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASI-------TKQVFADITKTS 168 P + T + G + I YGDGSS+ G ++ D+V GG + +Q+ A + + Sbjct: 58 NPSA-TGKELSGYTWSISYGDGSSASGNVFTDSVTVGGVTAHGQAVQAAQQISAQFQQDT 116 Query: 169 IPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAK 228 G+LG+ + + + +A+ +++ L + G FG +D +K Sbjct: 117 NNDGLLGLAFSSINTVQPQSQTTFFDTVKSSLAQPLFAVALK--HQQPGVYDFGFIDSSK 174 Query: 229 YSGSLIAVPVTSDRE-LRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAF 287 Y+GSL V + + ++S A ++ + + D+GTT+ L V Sbjct: 175 YTGSLTYTGVDNSQGFWSFNVDSYTAGSQSGD-GFSGIADTGTTLLLLDDSVVSQYYSQV 233 Query: 288 QAELKSDGQGHTFYVTDCQTSGTVDFNFDNNAKI-SVPASEFTAPLSYANGQPYPKCQLL 346 + G YV DC T DF+ + +VP S S Q Sbjct: 234 SGAQQDSNAGG--YVFDCST-NLPDFSVSISGYTATVPGSLINYGPSGDGSTCLGGIQSN 290 Query: 347 LGISDANILGDNFLRSAYLVYDLDDDKISLAQ 378 GI +I GD FL+S Y+V+D D ++ A Sbjct: 291 SGIG-FSIFGDIFLKSQYVVFDSDGPQLGFAP 321 >4OC6-B nrPDB Length = 243 Score = 219 bits (557), Expect = 2e-57, Method: Composition-based stats. Identities = 55/245 (22%), Positives = 101/245 (41%), Gaps = 22/245 (8%) Query: 152 GGASITKQVFADITKTSI-------PQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNA 204 GG + +QVF + TK GILG+ Y + + V L Q ++ +N Sbjct: 1 GGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRI-SVNNVLPVFDNLMQQKLVDQNI 59 Query: 205 YSLYLNSPNAA--TGQIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVG--KNING 260 +S YL+ A G+++ GG D Y GSL + VT ++ L+ ++ Sbjct: 60 FSFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKE 119 Query: 261 NIDVLLDSGTTITYLQQDVAQDIIDAFQAELKSDGQGHTFYVTDCQTSGTVD-FNFDNNA 319 + ++D+GT++ D +++ A A G+ Y+ C+ T+ Sbjct: 120 GCEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGE----YMIPCEKVSTLPAITLKLGG 175 Query: 320 K-ISVPASEFTAPLSYA----NGQPYPKCQLLLGISDANILGDNFLRSAYLVYDLDDDKI 374 K + ++T +S A + + ILGD F+ Y V+D D++++ Sbjct: 176 KGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRV 235 Query: 375 SLAQV 379 A+ Sbjct: 236 GFAEA 240 >5HCT-A nrPDB Length = 419 Score = 211 bits (537), Expect = 5e-55, Method: Composition-based stats. Identities = 93/351 (26%), Positives = 147/351 (41%), Gaps = 28/351 (7%) Query: 40 NATGQEGKVKRQAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDK 99 + +G + A +++ +Y + IG+ Q N+ DTGSSDLWV + Sbjct: 82 STSGLAERSTGSATTTPIDSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSET---- 137 Query: 100 PRPGQSADFCKGKGIYTPKSSTTSQNL-GTPFYIGYGDGSSSQGTLYKDTVGFGGASITK 158 +A G+ IYTP STT++ L G + I YGDGSSS G +Y DTV GG ++T Sbjct: 138 -----TASEVDGQTIYTPSKSTTAKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTG 192 Query: 159 QVFA-------DITKTSIPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNS 211 Q T+ S G+LG+ + T + + ++ L Sbjct: 193 QAVESAKKVSSSFTEDSTIDGLLGLAFSTLNTVSPTQQKTFFDNAKASLDSPVFTADLGY 252 Query: 212 PNAATGQIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNI--NGNIDVLLDSG 269 A G FG +D Y+GS+ V++ + ++ AVG + +ID + D+G Sbjct: 253 H--APGTYNFGFIDTTAYTGSITYTAVSTKQGFWEWTSTGYAVGSGTFKSTSIDGIADTG 310 Query: 270 TTITYLQQDVAQDIIDAFQAELKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFT 329 TT+ YL V S G YV C + F F + V ++ Sbjct: 311 TTLLYLPATVVSAYWAQVSGAKSSSSVGG--YVFPCSAT-LPSFTFGVGSARIVIPGDYI 367 Query: 330 --APLSYANGQPYPKCQLLLGISDANILGDNFLRSAYLVYD-LDDDKISLA 377 P+S + + Q GI NI GD L++A++V++ + A Sbjct: 368 DFGPISTGSSSCFGGIQSSAGIG-INIFGDVALKAAFVVFNGATTPTLGFA 417 >4B1C-A nrPDB Length = 375 Score = 207 bits (527), Expect = 6e-54, Method: Composition-based stats. Identities = 78/366 (21%), Positives = 144/366 (39%), Gaps = 57/366 (15%) Query: 49 KRQAIPVTLNNEHVS---YAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQS 105 K + + N S Y ++T+GS Q N++VDTGSS+ V A P P Sbjct: 2 KGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAA------PHPFL- 54 Query: 106 ADFCKGKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGF-GGASITKQV-FAD 163 Y + S+T ++L Y+ Y G +G L D V G ++T + A Sbjct: 55 ------HRYYQRQLSSTYRDLRKGVYVPYTQGKW-EGELGTDLVSIPHGPNVTVRANIAA 107 Query: 164 ITKT-------SIPQGILGIGYKTNE-AAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAA 215 IT++ S +GILG+ Y + +L Q N +SL L + Sbjct: 108 ITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQ-THVPNLFSLQLCGGGSM 166 Query: 216 TGQIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNINGNI------DVLLDSG 269 I D + Y+GSL P+ + + + ++ G+++ + ++DSG Sbjct: 167 IIGGI----DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSG 222 Query: 270 TTITYLQQDVAQDIIDAFQAELKSDGQGHTFYVTD---CQTSGTVDFNF----------- 315 TT L + V + + + +A ++ F++ + C +GT +N Sbjct: 223 TTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGE 282 Query: 316 --DNNAKISVPASEFTAPLSYANGQPYPKCQ--LLLGISDANILGDNFLRSAYLVYDLDD 371 + + +I++ ++ P+ C + S ++G + Y+V+D Sbjct: 283 VTNQSFRITILPQQYLRPVEDV-ATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRAR 341 Query: 372 DKISLA 377 +I A Sbjct: 342 KRIGFA 347 >3EMY-A nrPDB Length = 329 Score = 204 bits (518), Expect = 6e-53, Method: Composition-based stats. Identities = 87/342 (25%), Positives = 139/342 (40%), Gaps = 27/342 (7%) Query: 49 KRQAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADF 108 A ++ Y ++IG+ Q + DTGSSDLWV + Sbjct: 2 TGSAPNHPSDSADSEYITSVSIGTPAQVLPLDFDTGSSDLWVFSSET---------PKSS 52 Query: 109 CKGKGIYTP-KSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKT 167 G IYTP KSST+ + G + I YGDGSSS G +Y D V GG S+ Q T+ Sbjct: 53 ATGHAIYTPSKSSTSKKVSGASWSISYGDGSSSSGDVYTDKVTIGGFSVNTQGVESATRV 112 Query: 168 S-------IPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQII 220 S + G++G+ + + + +A+ ++ L + G Sbjct: 113 STEFVQDTVISGLVGLAFDSGNQVRPHPQKTWFSNAASSLAEPLFTADLR--HGQNGSYN 170 Query: 221 FGGVDKAKYSGSLIAVPVTSDRE-LRITLNSLKAVGKNING-NIDVLLDSGTTITYLQQD 278 FG +D + G + PV + + T + G +N +ID + D+GTT+ L + Sbjct: 171 FGYIDTSVAKGPVAYTPVDNSQGFWEFTASGYSVGGGKLNRNSIDGIADTGTTLLLLDDN 230 Query: 279 VAQDIIDAFQAELKSDGQGHTFYVTDCQTSGTVDFNFDNN-AKISVPASEFTA-PLSYAN 336 V + V DC F+F + I++P PL + Sbjct: 231 VVDAYY--ANVQSAQYDNQQEGVVFDCDE-DLPSFSFGVGSSTITIPGDLLNLTPLEEGS 287 Query: 337 GQPYPKCQLLLGISDANILGDNFLRSAYLVYDLDDDKISLAQ 378 + Q GI NI GD L++A +V+DL ++++ AQ Sbjct: 288 STCFGGLQSSSGIG-INIFGDVALKAALVVFDLGNERLGWAQ 328 >3ZKX-A nrPDB Length = 386 Score = 201 bits (512), Expect = 3e-52, Method: Composition-based stats. Identities = 65/353 (18%), Positives = 135/353 (38%), Gaps = 54/353 (15%) Query: 64 YAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTTS 123 Y ++ IG+ QK ++VDTGSS+ V + + + S+T Sbjct: 18 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHS-------------YIDTYFDTERSSTY 64 Query: 124 QNLGTPFYIGYGDGSSSQGTLYKDTVGF--GGASITKQVFADITKTSIP-------QGIL 174 ++ G + Y GS + G + +D V G + A I ++ GIL Sbjct: 65 RSKGFDVTVKYTQGSWT-GFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGIL 123 Query: 175 GIGYKT-NEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPN-------AATGQIIFGGVDK 226 G+ Y T + + + +L Q I N +S+ + G ++ GG++ Sbjct: 124 GLAYATLAKPSSSLETFFDSLVTQANI-PNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEP 182 Query: 227 AKYSGSLIAVPVTSDRELRITLNSLKAVGKNINGNI------DVLLDSGTTITYLQQDVA 280 + Y G + P+ + +I + L+ G+++N + ++DSGTT+ L Q V Sbjct: 183 SLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVF 242 Query: 281 QDIIDAFQAELKSDGQGHTFYVTD---CQTSGTVDFNF-------------DNNAKISVP 324 +++A F+ C T+ +++ + +I++ Sbjct: 243 DAVVEAVARASLIPAFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENSSRSFRITIL 302 Query: 325 ASEFTAPLSYANGQPYPKCQLLLGISDANILGDNFLRSAYLVYDLDDDKISLA 377 + P+ A + ++A ++G + Y+++D ++ A Sbjct: 303 PQLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVIFDRAQKRVGFA 355 >3PI0-A nrPDB Length = 330 Score = 198 bits (504), Expect = 3e-51, Method: Composition-based stats. Identities = 92/342 (26%), Positives = 143/342 (41%), Gaps = 28/342 (8%) Query: 49 KRQAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADF 108 A +++ +Y + IG+ Q N+ DTGSSDLWV + +A Sbjct: 2 TGSATTTPIDSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSET---------TASE 52 Query: 109 CKGKGIYTPKSSTTSQNL-GTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFA----- 162 G+ IYTP STT++ L G + I YGDGSSS G +Y DTV GG ++T Q Sbjct: 53 VDGQTIYTPSKSTTAKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTGQAVESAKKV 112 Query: 163 --DITKTSIPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQII 220 T+ S G+LG+ + T + + ++ L A G Sbjct: 113 SSSFTEDSTIDGLLGLAFSTLNTVSPTQQKTFFDNAKASLDSPVFTADLGYH--APGTYN 170 Query: 221 FGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNI--NGNIDVLLDSGTTITYLQQD 278 FG +D Y+GS+ V++ + ++ AVG + +ID + D+GTT+ YL Sbjct: 171 FGFIDTTAYTGSITYTAVSTKQGFWEWTSTGYAVGSGTFKSTSIDGIADTGTTLLYLPAT 230 Query: 279 VAQDIIDAFQAELKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFT--APLSYAN 336 V S G YV C + F F + V ++ P+S + Sbjct: 231 VVSAYWAQVSGAKSSSSVGG--YVFPCSAT-LPSFTFGVGSARIVIPGDYIDFGPISTGS 287 Query: 337 GQPYPKCQLLLGISDANILGDNFLRSAYLVYD-LDDDKISLA 377 + Q GI NI GD L++A++V++ + A Sbjct: 288 SSCFGGIQSSAGIG-INIFGDVALKAAFVVFNGATTPTLGFA 328 >1WKR-A nrPDB Length = 340 Score = 179 bits (455), Expect = 2e-45, Method: Composition-based stats. Identities = 83/353 (23%), Positives = 137/353 (38%), Gaps = 53/353 (15%) Query: 51 QAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCK 110 ++P T N+ V Y ++ +GS ++++VDTGSS+ W+ Sbjct: 3 GSVPAT--NQLVDYVVNVGVGSPATTYSLLVDTGSSNTWLGADKSYV------------- 47 Query: 111 GKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP 170 ++TS + YG GS S GT Y DTV G +I KQ ++ S Sbjct: 48 --------KTSTSSATSDKVSVTYGSGSFS-GTEYTDTVTLGSLTIPKQSIGVASRDSGF 98 Query: 171 QGILGI----------GYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLN---SPNAATG 217 G+ GI G + + V L +QG I N ++ S ++ G Sbjct: 99 DGVDGILGVGPVDLTVGTLSPHTSTSIPTVTDNLFSQGTIPTNLLAVSFEPTTSESSTNG 158 Query: 218 QIIFGGVDKAKYSGSLIAVPVTS----DRELRITLNSLKAVGKNINGNIDVLLDSGTTIT 273 ++ FG D +KY+GS+ P+TS I + +I + ++D+GTT+T Sbjct: 159 ELTFGATDSSKYTGSITYTPITSTSPASAYWGINQSIRYGSSTSILSSTAGIVDTGTTLT 218 Query: 274 YLQQDVAQDIIDAFQAELKSDGQGHTFYVTDCQTSGTVDFNFDNNAKI---SVPASEFTA 330 + D A A +D +T Q + F + + A + Sbjct: 219 LIASDAFAKYKKATGA--VADNNTGLLRLTTAQYANLQSLFFTIGGQTFELTANAQIWPR 276 Query: 331 PLSYANGQPYPKCQLLLGISDAN-------ILGDNFLRSAYLVYDLDDDKISL 376 L+ A G L++G ++ I G FL Y VYD + ++ L Sbjct: 277 NLNTAIGGSASSVYLIVGDLGSDSGEGLDFINGLTFLERFYSVYDTTNKRLGL 329 >3O9L-A nrPDB Length = 166 Score = 159 bits (401), Expect = 3e-39, Method: Composition-based stats. Identities = 43/169 (25%), Positives = 83/169 (49%), Gaps = 17/169 (10%) Query: 52 AIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKG 111 + + N Y +I IG+ Q F V+ DTGSS++WVP + + + C Sbjct: 8 SSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCS-------RLYTACVY 60 Query: 112 KGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKT---- 167 ++ S++ ++ GT + Y G+ S G L +D + GG ++T Q+F ++T+ Sbjct: 61 HKLFDASDSSSYKHNGTELTLRYSTGTVS-GFLSQDIITVGGITVT-QMFGEVTEMPALP 118 Query: 168 ---SIPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPN 213 + G++G+G+ +A G + + +QGV+ ++ +S Y N + Sbjct: 119 FMLAEFDGVVGMGF-IEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDS 166 >3OAD-B nrPDB Length = 176 Score = 145 bits (366), Expect = 3e-35, Method: Composition-based stats. Identities = 34/178 (19%), Positives = 68/178 (38%), Gaps = 19/178 (10%) Query: 214 AATGQIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKN--INGNIDVLLDSGTT 271 + GQI+ GG D Y G+ + + +I + + L+D+G + Sbjct: 1 SLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGAS 60 Query: 272 ITYLQQDVAQDIIDAFQAELKSDGQGHTFYVTDCQTSGT-VDFNFDNNAK-ISVPASEFT 329 + +++A A+ + YV C T D +F K ++ ++++ Sbjct: 61 YISGSTSSIEKLMEALGAKKR-----LFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYV 115 Query: 330 APLSYANGQPYPKCQLLLGISDA-------NILGDNFLRSAYLVYDLDDDKISLAQVK 380 SY++ + C L + D LG F+R Y +D +++I A + Sbjct: 116 FQESYSSKK---LCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR 170 >3LIZ-A nrPDB Length = 334 Score = 129 bits (323), Expect = 3e-30, Method: Composition-based stats. Identities = 59/327 (18%), Positives = 108/327 (33%), Gaps = 28/327 (8%) Query: 61 HVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSS 120 + YA IG Q F + D+ S + V AS C A C Y Sbjct: 18 NTQYAGITKIG--NQNFLTVFDSTSCN--VVVASQECVGG-----ACVCPNLQKYEKLKP 68 Query: 121 TTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTS------IPQGIL 174 + G + + D S+ G +D++ + ++Q + S ++ Sbjct: 69 K-YISDG-NVQVKFFDTGSAVGRGIEDSLTISQLTTSQQDIVLADELSQEVCILSADVVV 126 Query: 175 GIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNS--PNAATGQIIFGGVDKAKYSGS 232 GI A V + +IA +S++ G+IIFGG D G Sbjct: 127 GIAAPGCPNALKGKTVLENFVEENLIA-PVFSIHHARFQDGEHFGEIIFGGSDWKYVDGE 185 Query: 233 LIAVPVTSDRELRITLNSLKAVGKNIN-GNIDVLLDSGTTITYLQQDVAQDIIDAFQAEL 291 VP+ D + L+ +K + ++D+ I + I +A + Sbjct: 186 FTYVPLVGDDSWKFRLDGVKIGDTTVAPAGTQAIIDTSKAIIVGPKAYVNPINEAIGCVV 245 Query: 292 KSDGQGHTFYVTDCQTSGT-VDFNFD-NNAKISVPASEFTAPLSYANGQPYPKCQLLLGI 349 + + DC + D F N ++ + + + C G Sbjct: 246 EKTTTRRICKL-DCSKIPSLPDVTFVINGRNFNISSQYYIQQNGNLCYSGFQPC----GH 300 Query: 350 SDANILGDNFLRSAYLVYDLDDDKISL 376 SD +GD F+ Y ++ ++ + Sbjct: 301 SDHFFIGDFFVDHYYSEFNWENKTMGF 327 >4OD9-A nrPDB Length = 103 Score = 121 bits (304), Expect = 5e-28, Method: Composition-based stats. Identities = 39/105 (37%), Positives = 45/105 (42%), Gaps = 9/105 (8%) Query: 48 VKRQAIPVTL-NNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSA 106 V IP L N Y +I IG+ Q F V+ DTGSS+LWVP Sbjct: 3 VTEGPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCK-------LLD 55 Query: 107 DFCKGKGIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGF 151 C Y S+T GT F I YG GS S G L +DTV Sbjct: 56 IACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLS-GYLSQDTVSV 99 >4ZL4-A nrPDB Length = 444 Score = 87.4 bits (215), Expect = 9e-18, Method: Composition-based stats. Identities = 70/428 (16%), Positives = 135/428 (31%), Gaps = 131/428 (30%) Query: 58 NNEHVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTP 117 +E+ Y DI IG+ +Q+ ++I+DTGSS L P A + + Sbjct: 24 IDEYAYYFLDIDIGTPEQRISLILDTGSSSLSFPCAGCK---------NCGVHMENPFNL 74 Query: 118 KSSTTS-----QNLGTPFYI-----------GYGDGSSSQGTLYKDTVGFGGASITKQVF 161 +S TS +N PF + Y +GS G + D V S + Sbjct: 75 NNSKTSSILYCENEECPFKLNCVKGKCEYMQSYCEGSQISGFYFSDVVSV--VSYNNERV 132 Query: 162 ------------ADITKTSIPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYL 209 + G+LG+ + + N+ Q K +++ + Sbjct: 133 TFRKLMGCHMHEESLFLYQQATGVLGMSLSKPQGIPTFVNLLFDNAPQ---LKQVFTICI 189 Query: 210 NSPNAATGQIIFGGVDKAK-----------YSGS-----------------------LIA 235 + G++I GG D A GS ++ Sbjct: 190 S---ENGGELIAGGYDPAYIVRRGGSKSVSGQGSGPVSESLSESGEDPQVALREAEKVVW 246 Query: 236 VPVTSDRELRITLNSLKAVGK---NINGNIDVLLDSGTTITYLQQDVAQDI--------- 283 VT I + L G + + +++L+DSG+T T++ +D+ + Sbjct: 247 ENVTRKYYYYIKVRGLDMFGTNMMSSSKGLEMLVDSGSTFTHIPEDLYNKLNYFFDILCI 306 Query: 284 ---IDAFQA----ELKSDGQGHTFYVTD------------------------CQTS--GT 310 +A+ ++ ++ + D C G Sbjct: 307 QDMNNAYDVNKRLKMTNESFNNPLVQFDDFRKSLKSIIAKENMCVKIVDGVQCWKYLEGL 366 Query: 311 VDF--NFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGISDANILGDNFLRSAYLVYD 368 D NN K+ + + K +++ ILG F ++ +++D Sbjct: 367 PDLFVTLSNNYKMKWQPHSYLYKKESFWCKGIEK-----QVNNKPILGLTFFKNRQVIFD 421 Query: 369 LDDDKISL 376 + ++I Sbjct: 422 IQKNRIGF 429 >1B5F-B nrPDB Length = 87 Score = 62.8 bits (151), Expect = 3e-10, Method: Composition-based stats. Identities = 14/82 (17%), Positives = 28/82 (34%), Gaps = 5/82 (6%) Query: 303 TDCQTSGTVD-FNFDNNAK-ISVPASEFTAPLSYANGQPYPKC---QLLLGISDANILGD 357 DC T ++ +F K + ++ + + ILGD Sbjct: 5 VDCNTLSSMPNVSFTIGGKKFGLTPEQYILKVGKGEATQCISGFTAMDATLLGPLWILGD 64 Query: 358 NFLRSAYLVYDLDDDKISLAQV 379 F+R + V+D + + A+ Sbjct: 65 VFMRPYHTVFDYGNLLVGFAEA 86 >4PPH-A nrPDB Length = 417 Score = 44.6 bits (104), Expect = 8e-05, Method: Composition-based stats. Identities = 59/373 (15%), Positives = 120/373 (32%), Gaps = 80/373 (21%) Query: 72 SNKQKFNVIVDTGSSDLWVPDASVTCDKPR--PGQSADFCK---GKGIYTPKSSTTSQ-- 124 + + +++D LWV + P + C +T STT++ Sbjct: 36 TPLMQVPLLLDLNGKHLWVTCSQHYSSSTYQAPFCHSTQCSRANTHQCFTCTDSTTTRPG 95 Query: 125 -NLGTPFYIGYG--DGSSSQGTLYKDTVGFGG---------ASITKQVFADITKT----- 167 + T + S G L +D + + + +F+ Sbjct: 96 CHNNTCGLLSSNPVTQESGLGELAQDVLAIHSTHGSKLGPMVKVPQFLFSCAPSFLAQKG 155 Query: 168 --SIPQGILGIGYKTNEAAGDYDNVPVTLKNQ---GVIAKNAYSLYLNSPNAATGQIIFG 222 + QG LG+G P++L+NQ K +S+ L+ + + G I+FG Sbjct: 156 LPNNVQGALGLG-----------QAPISLQNQLFSHFGLKRQFSVCLSRYSTSNGAILFG 204 Query: 223 GV-DKAKYSG---------SLIAVPVT--SDRELRITLNSLKAV---------------G 255 + D + L+ P+T E I +N+++ Sbjct: 205 DINDPNNNNYIHNSLDVLHDLVYTPLTISKQGEYFIQVNAIRVNKHLVIPTKNPFISPSS 264 Query: 256 KNINGNID---VLLDSGTTITYLQQDVAQDIIDAF------QAELKSDGQGHTFYVTDCQ 306 + +G+ + L+ + T L + + F QA++K+ G Y + Sbjct: 265 TSYHGSGEIGGALITTTHPYTVLSHSIFEVFTQVFANNMPKQAQVKAVGPFGLCYDSRKI 324 Query: 307 TSGTVDFNF---DNNAKISVPASEFTAPLSYANGQPYPKCQLLLGISDANILGDNFLRSA 363 + G + N+A + + F + LG + L Sbjct: 325 SGGAPSVDLILDKNDAVWRISSENFMVQAQDG-VSCLGFVDGGVHARAGIALGAHHLEEN 383 Query: 364 YLVYDLDDDKISL 376 +V+DL+ ++ Sbjct: 384 LVVFDLERSRVGF 396 >3AUP-A nrPDB Length = 403 Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 60/367 (16%), Positives = 101/367 (27%), Gaps = 77/367 (20%) Query: 72 SNKQKFNVIVDTGSSDLWVPDASVTCDKPR--PGQSADFCKGKGIYT----PKSSTTSQN 125 + + V+VD + LWV K P + C + P +S + Sbjct: 31 TPLMQVPVLVDLNGNHLWVNCEQQYSSKTYQAPFCHSTQCSRANTHQCLSCPAASRPGCH 90 Query: 126 LGT-----PFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIP---------- 170 T I G G L +D + + Q + Sbjct: 91 KNTCGLMSTNPITQQTG---LGELGEDVLAIHATQGSTQQLGPLVTVPQFLFSCAPSFLV 147 Query: 171 --------QGILGIGYKTNEAAGDYDNVPVTLKNQ---GVIAKNAYSLYLNSPNAATGQI 219 QG+ G+G+ P++L NQ + ++ L+ + G I Sbjct: 148 QKGLPRNTQGVAGLGHA-----------PISLPNQLASHFGLQRQFTTCLSRYPTSKGAI 196 Query: 220 IFGGVDKAKYS-------GSLIAVP--VTSDRELRITLNSLKAV----------GKNING 260 IFG L P +T E + +NS++ I G Sbjct: 197 IFGDAPNNMRQFQNQDIFHDLAFTPLTITLQGEYNVRVNSIRINQHSVFPLNKISSTIVG 256 Query: 261 NIDV--LLDSGTTITYLQQDVAQDIIDAFQAELKSDGQGHTF-YVTDC------QTSGTV 311 + ++ + T LQQ V Q F +L Q + C +V Sbjct: 257 STSGGTMISTSTPHMVLQQSVYQAFTQVFAQQLPKQAQVKSVAPFGLCFNSNKINAYPSV 316 Query: 312 DFNFD--NNAKISVPASEFTAPLSYANGQPYPKCQLLLGISDANILGDNFLRSAYLVYDL 369 D D N + + + LG L +V+DL Sbjct: 317 DLVMDKPNGPVWRISGEDLMVQAQ-PGVTCLGVMNGGMQPRAEITLGARQLEENLVVFDL 375 Query: 370 DDDKISL 376 ++ Sbjct: 376 ARSRVGF 382 >2BKL-A nrPDB Length = 695 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 23/55 (41%) Query: 35 IKTPVNATGQEGKVKRQAIPVTLNNEHVSYAADITIGSNKQKFNVIVDTGSSDLW 89 +K T Q V + + L + +Y + + +Q + V TG S+LW Sbjct: 349 LKGKPVRTVQLPGVGAASNLMGLEDLDDAYYVFTSFTTPRQIYKTSVSTGKSELW 403 >1QU3-A nrPDB Length = 917 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 20/99 (20%), Positives = 31/99 (31%), Gaps = 8/99 (8%) Query: 71 GSNKQKFN-------VIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTTS 123 GS F V D+GSS V + P + +G + +T+ Sbjct: 512 GSPNGTFTKETDIMDVWFDSGSSHRGVLETRPELSFPADMYLEGSDQYRGWFNSSITTSV 571 Query: 124 QNLG-TPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVF 161 G +P+ G G K + G + QV Sbjct: 572 ATRGVSPYKFLLSHGFVMDGEGKKMSKSLGNVIVPDQVV 610 >4WJ3-M nrPDB Length = 599 Score = 29.6 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 3/78 (3%) Query: 152 GGASITKQVFADITKTSIPQGILGIGY-KTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLN 210 G AS+ + D TK G G+ Y K NE A + + + I + ++ L+ Sbjct: 336 GAASMPRSQIDDYTKFVGIYGAKGLAYIKVNERAKGVEGLQSPIVK--FIPEANLNVILD 393 Query: 211 SPNAATGQIIFGGVDKAK 228 A G I+F G DKAK Sbjct: 394 RVGAVDGDIVFFGADKAK 411 >1T6G-A nrPDB Length = 381 Score = 28.9 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 50/324 (15%), Positives = 90/324 (27%), Gaps = 54/324 (16%) Query: 91 PDASVTCDKPRPGQSADFCKGKGIYTPKSSTTS--QNLGTPFYIGYGDGSSSQGTLYKDT 148 P + C Y P S + T F DGS + K Sbjct: 62 PAPGCPAPSCGSDKHDKPCTAYP-YNPVSGACAAGSLSHTRFVANTTDGSKP---VSKVN 117 Query: 149 VGFGGASITKQVFADITKTSIPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLY 208 VG A ++ A + + S G+ G+ +P + + +A Sbjct: 118 VGVLAACAPSKLLASLPRGST--GVAGLANSGLA-------LPAQVASAQKVANR---FL 165 Query: 209 LNSPNAATGQIIFGG--VDKAKYSGSLIAVPVTSDRELRITL--NSLKAVGKNINGNIDV 264 L P G IFGG V +++ S+ P+ + VG + Sbjct: 166 LCLPTGGPGVAIFGGGPVPWPQFTQSMPYTPLVTKGGSPAHYISARSIVVGDTRVPVPEG 225 Query: 265 LLDSGTTIT-------YLQQDVAQDIIDAF----------QAELKSDGQGHTFYVTDCQT 307 L +G + L+ DV + ++DAF A + + + T Sbjct: 226 ALATGGVMLSTRLPYVLLRPDVYRPLMDAFTKALAAQHANGAPVARAVEAVAPFGVCYDT 285 Query: 308 -----------SGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGISDAN--- 353 V D + ++ + + D Sbjct: 286 KTLGNNLGGYAVPNVQLGLDGGSDWTMTGKNSMVDVKQGTACVAFVEMKGVAAGDGRAPA 345 Query: 354 -ILGDNFLRSAYLVYDLDDDKISL 376 ILG + L +D++ ++ Sbjct: 346 VILGGAQMEDFVLDFDMEKKRLGF 369 >1EBD-A nrPDB Length = 455 Score = 28.9 bits (63), Expect = 4.0, Method: Composition-based stats. Identities = 29/138 (21%), Positives = 46/138 (33%), Gaps = 25/138 (18%) Query: 28 VTLDFDVI---KTPVNAT---GQEGKVKRQAIPVTLNNEHVSYAAD-----ITIGSNKQK 76 VT+DF + K V G EG +K + + + +Y D + G + Q Sbjct: 75 VTIDFAKVQEWKASVVKKLTGGVEGLLKGNKVEIV---KGEAYFVDANTVRVVNGDSAQT 131 Query: 77 FNV---IVDTGSSDLWVPDASVTCD--------KPRPGQSADFCKGKGIYTPKSSTTSQN 125 + I+ TGS + +P+ + + G G + T N Sbjct: 132 YTFKNAIIATGSRPIELPNFKFSNRILDSTGALNLGEVPKSLVVIGGGYIGIELGTAYAN 191 Query: 126 LGTPFYIGYGDGSSSQGT 143 GT I G G G Sbjct: 192 FGTKVTILEGAGEILSGF 209 >4LUJ-A nrPDB Length = 233 Score = 28.5 bits (62), Expect = 5.1, Method: Composition-based stats. Identities = 9/45 (20%), Positives = 17/45 (37%), Gaps = 2/45 (4%) Query: 128 TPFYIGYGDGSSSQGTLYKDTV-GFGGASIT-KQVFADITKTSIP 170 + Y DG G + +D+V + + +T+ S P Sbjct: 93 AKITLKYADGIIVHGFVGEDSVKAVQDVAKKLNKKVIMVTEMSHP 137 >3U14-A nrPDB Length = 535 Score = 28.5 bits (62), Expect = 5.1, Method: Composition-based stats. Identities = 34/173 (19%), Positives = 56/173 (32%), Gaps = 32/173 (18%) Query: 68 ITIGSNKQKFNV-IVDTGSSDL--WVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTTSQ 124 I + S Q++ + I GS++L WV +++ + I S Sbjct: 192 IMVVSKSQEYKIQIF--GSANLKNWVLNSNFSSGYYGNQYECPGLIEVPIENSDKSKWVM 249 Query: 125 NLGTPFYIGYGD---GSSSQGTLYK---------DT----VGFGGASITKQVFADITKTS 168 I G GS +Q + D+ V G Q F+++ Sbjct: 250 ----FLAINPGSPLGGSINQYFVGDFDGFQFVPDDSQTRFVDIGKDFYAFQTFSEVEH-- 303 Query: 169 IPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIF 221 G+LG+ + +N D VP Y+L NA T Q+ Sbjct: 304 ---GVLGLAWASN--WQYADQVPTNPWRSSTSLARNYTLRYVHTNAETKQLTL 351 >3Q31-A nrPDB Length = 244 Score = 28.5 bits (62), Expect = 5.1, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 24/56 (42%), Gaps = 11/56 (19%) Query: 200 IAKNAYSLYLNSPNAAT----GQIIFGGVDKAK-------YSGSLIAVPVTSDREL 244 + + ++ N P+A T GQ+ FGG+ Y+GSL P T + Sbjct: 144 LFDSVFAPIDNIPDAGTSTTTGQLDFGGLLDHFNRHGVYQYTGSLTTPPCTEEVMW 199 >3CP8-A nrPDB Length = 641 Score = 28.5 bits (62), Expect = 5.8, Method: Composition-based stats. Identities = 16/54 (29%), Positives = 25/54 (46%), Gaps = 1/54 (1%) Query: 181 NEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKA-KYSGSL 233 E GD D VP + + V +N S YL T I+ G D++ ++G + Sbjct: 232 TEQPGDVDPVPFSFSSTSVANRNLVSCYLTKTTEKTHDILRTGFDRSPLFTGKV 285 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.136 0.383 Lambda K H 0.267 0.0418 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,531,744 Number of Sequences: 36641 Number of extensions: 658046 Number of successful extensions: 2037 Number of sequences better than 10.0: 72 Number of HSP's better than 10.0 without gapping: 120 Number of HSP's successfully gapped in prelim test: 33 Number of HSP's that attempted gapping in prelim test: 1428 Number of HSP's gapped (non-prelim): 169 length of query: 391 length of database: 10,336,785 effective HSP length: 99 effective length of query: 292 effective length of database: 6,709,326 effective search space: 1959123192 effective search space used: 1959123192 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 60 (27.7 bits)