BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P0AFL3 (190 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1VAI-A nrPDB 341 1e-94 2NUL-A nrPDB 174 2e-44 3S6M-A nrPDB 173 4e-44 3T1U-A nrPDB 163 4e-41 2HQ6-A nrPDB 83 7e-17 4R3E-A nrPDB 83 8e-17 2A2N-A nrPDB 82 9e-17 5YZG-2 nrPDB 82 1e-16 5Z56-z nrPDB 82 1e-16 2MVZ-A nrPDB 81 3e-16 1XWN-A nrPDB 80 5e-16 2K7N-A nrPDB 80 6e-16 3JB9-d nrPDB 78 2e-15 2OK3-A nrPDB 75 2e-14 1ZKC-A nrPDB 71 3e-13 2B71-A nrPDB 70 7e-13 3K2C-A nrPDB 68 2e-12 2HAQ-A nrPDB 67 3e-12 3ICH-A nrPDB 65 2e-11 5EX2-A nrPDB 65 2e-11 4E1Q-A nrPDB 65 2e-11 6HIX-BQ nrPDB 65 3e-11 4HY7-A nrPDB 64 3e-11 4R3F-A nrPDB 64 4e-11 4JJM-A nrPDB 64 5e-11 5EX1-A nrPDB 64 5e-11 3BO7-A nrPDB 63 7e-11 5O9Z-M nrPDB 63 8e-11 5MQF-o nrPDB 63 1e-10 2QER-A nrPDB 62 1e-10 2MC9-A nrPDB 62 1e-10 4EYV-A nrPDB 62 1e-10 3UCH-A nrPDB 62 1e-10 3RDD-A nrPDB 62 1e-10 5TA2-A nrPDB 62 2e-10 2HQJ-A nrPDB 61 3e-10 1XQ7-A nrPDB 61 3e-10 2POY-A nrPDB 60 4e-10 2FU0-A nrPDB 60 4e-10 3PMP-A nrPDB 60 6e-10 3R49-A nrPDB 59 9e-10 1H0P-A nrPDB 59 2e-09 6HMZ-X nrPDB 58 2e-09 5YB9-A nrPDB 58 3e-09 3BKP-A nrPDB 57 5e-09 2CMT-A nrPDB 57 7e-09 4JCP-A nrPDB 56 7e-09 1C5F-A nrPDB 55 2e-08 6HIX-BZ nrPDB 53 8e-08 2RMC-A nrPDB 52 1e-07 2CFE-A nrPDB 52 1e-07 1IST-A nrPDB 52 2e-07 1QNH-A nrPDB 51 2e-07 2C3B-A nrPDB 51 3e-07 1E8K-A nrPDB 50 4e-07 2ESL-A nrPDB 50 4e-07 4I9Y-A nrPDB 50 8e-07 1W74-A nrPDB 49 9e-07 2HE9-A nrPDB 49 2e-06 1IHG-A nrPDB 48 2e-06 2WFI-A nrPDB 48 3e-06 1Z81-A nrPDB 47 4e-06 5YZG-3 nrPDB 44 3e-05 3RFY-A nrPDB 42 2e-04 5JHE-A nrPDB 34 0.029 5GM6-b nrPDB 33 0.088 2JGP-A nrPDB 30 0.46 4V61-AG nrPDB 30 0.77 3AIC-A nrPDB 29 0.98 5VPU-A nrPDB 29 1.1 2OSE-A nrPDB 26 8.2 5M29-A nrPDB 26 8.4 >1VAI-A nrPDB Length = 166 Score = 341 bits (875), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 165/166 (99%), Positives = 165/166 (99%) Query: 25 AKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGF 84 AKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGF Sbjct: 1 AKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGF 60 Query: 85 TEQMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDF 144 TEQMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDF Sbjct: 61 TEQMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDF 120 Query: 145 GYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVLP 190 GYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSA VLP Sbjct: 121 GYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSATVLP 166 >2NUL-A nrPDB Length = 164 Score = 174 bits (441), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 90/161 (55%), Positives = 110/161 (68%), Gaps = 3/161 (1%) Query: 31 VLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQMQQ 90 V T+ G+I ++ KAP +V+NF+DY GFYNNT FHRVI GFMIQGGGF M+Q Sbjct: 2 VTFHTNHGDIVIKTFDDKAPETVKNFLDYCREGFYNNTIFHRVINGFMIQGGGFEPGMKQ 61 Query: 91 KKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLD---HGQRDFGYA 147 K PIKNEA+NGL+NTRGT+AMART SAT+QFFINV DN FL+ + +GY Sbjct: 62 KATKEPIKNEANNGLKNTRGTLAMARTQAPHSATAQFFINVVDNDFLNFSGESLQGWGYC 121 Query: 148 VFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKV 188 VF +VV GMDV DKI V T G +Q+VP + V+I S V Sbjct: 122 VFAEVVDGMDVVDKIKGVATGRSGMHQDVPKEDVIIESVTV 162 >3S6M-A nrPDB Length = 167 Score = 173 bits (438), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 92/162 (56%), Positives = 115/162 (70%), Gaps = 3/162 (1%) Query: 31 VLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQMQQ 90 V L T+ G I+LELD+ KAP +V+NF++YV G Y+ T FHRVI GFMIQGGGF ++Q Sbjct: 6 VELHTNHGVIKLELDEAKAPKTVENFLNYVKKGHYDGTIFHRVINGFMIQGGGFEPGLKQ 65 Query: 91 KKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQ---RDFGYA 147 K + PI NEA+NGL+N TIAMART D SAT+QFFINV DN FL+H + +GYA Sbjct: 66 KPTDAPIANEANNGLKNDTYTIAMARTNDPHSATAQFFINVNDNEFLNHSSPTPQGWGYA 125 Query: 148 VFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 VFGKVV+G D+ DKI V T G +Q+VP+ VVI A V+ Sbjct: 126 VFGKVVEGQDIVDKIKAVKTGSKGFHQDVPNDDVVIEKAVVV 167 >3T1U-A nrPDB Length = 163 Score = 163 bits (413), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 86/162 (53%), Positives = 106/162 (65%), Gaps = 3/162 (1%) Query: 31 VLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQMQQ 90 + L T+ G I L+L KAP + NF YV G Y+ T FHRVI GFMIQGGGF M+Q Sbjct: 2 IKLQTNHGTITLKLFADKAPETAANFEQYVKDGHYDGTIFHRVIDGFMIQGGGFEPGMKQ 61 Query: 91 KKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDH---GQRDFGYA 147 K PIKNEA+NGL N + TIAMART D SA++QFFINV DNAFLDH +GYA Sbjct: 62 KSTRAPIKNEANNGLSNKKYTIAMARTPDPHSASAQFFINVKDNAFLDHTAPTAHGWGYA 121 Query: 148 VFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 VFG+VV+G DV D+I V T + +VP V+I A+++ Sbjct: 122 VFGEVVEGTDVVDRIKSVATGSRAGHGDVPVDDVIIEKAEIV 163 >2HQ6-A nrPDB Length = 185 Score = 82.8 bits (203), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 61/176 (34%), Positives = 88/176 (50%), Gaps = 12/176 (6%) Query: 17 ALSPAAMAAKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPG 76 L P + VLL T+AG+I++EL ++AP + +NF+ +Y+NT FHRV+PG Sbjct: 13 GLVPRGSEPPTNGKVLLKTTAGDIDIELWSKEAPKACRNFIQLCLEAYYDNTIFHRVVPG 72 Query: 77 FMIQGGGFTEQMQQKKP--NPPIKNEADNGLR-NTRGTIAMARTADKDSATSQFFINVAD 133 F++QGG T + P K+E + LR N RG +AMA D+ SQFF + Sbjct: 73 FIVQGGDPTGTGSGGESIYGAPFKDEFHSRLRFNRRGLVAMANAGSHDNG-SQFFFTLGR 131 Query: 134 NAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 L++ FG V G V M ++S+V D P P I S +VL Sbjct: 132 ADELNNKHTIFG-KVTGDTVYNM---LRLSEVDIDD----DERPHNPHKIKSCEVL 179 >4R3E-A nrPDB Length = 180 Score = 82.8 bits (203), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 59/162 (36%), Positives = 85/162 (52%), Gaps = 12/162 (7%) Query: 31 VLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQMQQ 90 VLL T+AG+I++EL ++AP + +NF+ +Y+NT FHRV+PGF++QGG T Sbjct: 17 VLLKTTAGDIDIELWSKEAPKACRNFIQLCLEAYYDNTIFHRVVPGFIVQGGDPTGTGSG 76 Query: 91 KKP--NPPIKNEADNGLR-NTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYA 147 + P K+E + LR N RG +AMA D+ SQFF + L++ FG Sbjct: 77 GESIYGAPFKDEFHSRLRFNRRGLVAMANAGSHDNG-SQFFFTLGRADELNNKHTIFG-K 134 Query: 148 VFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 V G V M ++S+V D P P I S +VL Sbjct: 135 VTGDTVYNM---LRLSEVDIDD----DERPHNPHKIKSCEVL 169 >2A2N-A nrPDB Length = 176 Score = 82.4 bits (202), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 62/175 (35%), Positives = 93/175 (53%), Gaps = 16/175 (9%) Query: 21 AAMAAKGDPHV----LLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPG 76 AA A+G V ++ TS G+I +L + P +V+NF + +G+YN TFHR+I G Sbjct: 10 AATQAEGPKRVSDSAIIHTSMGDIHTKLFPVECPKTVENFCVHSRNGYYNGHTFHRIIKG 69 Query: 77 FMIQGGG--FTEQMQQKKPNPPIKNEADNGLRNTRG-TIAMARTADKDSATSQFFINVAD 133 FMIQ G T + ++E + LR+ R T++MA A ++ SQFFI V Sbjct: 70 FMIQTGDPTGTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMAN-AGSNTNGSQFFITVVP 128 Query: 134 NAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKV 188 +LD+ + VFG+V KGM+V +IS V V P + P + V I++ V Sbjct: 129 TPWLDN-----KHTVFGRVTKGMEVVQRISNV---KVNPKTDKPYEDVSIINITV 175 >5YZG-2 nrPDB Length = 646 Score = 82.4 bits (202), Expect = 1e-16, Method: Composition-based stats. Identities = 62/175 (35%), Positives = 93/175 (53%), Gaps = 16/175 (9%) Query: 21 AAMAAKGDPHV----LLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPG 76 AA A+G V ++ TS G+I +L + P +V+NF + +G+YN TFHR+I G Sbjct: 480 AATQAEGPKRVSDSAIIHTSMGDIHTKLFPVECPKTVENFCVHSRNGYYNGHTFHRIIKG 539 Query: 77 FMIQGGGFTEQMQQKKP--NPPIKNEADNGLRNTRG-TIAMARTADKDSATSQFFINVAD 133 FMIQ G T + ++E + LR+ R T++MA A ++ SQFFI V Sbjct: 540 FMIQTGDPTGTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMA-NAGSNTNGSQFFITVVP 598 Query: 134 NAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKV 188 +LD+ + VFG+V KGM+V +IS V V P + P + V I++ V Sbjct: 599 TPWLDN-----KHTVFGRVTKGMEVVQRISNV---KVNPKTDKPYEDVSIINITV 645 >5Z56-z nrPDB Length = 472 Score = 82.0 bits (201), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 59/164 (35%), Positives = 88/164 (53%), Gaps = 16/164 (9%) Query: 31 VLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQMQQ 90 VLL T+AG+I++EL ++AP + +NF+ +Y+NT FHRV+PGF++QGG T Sbjct: 15 VLLKTTAGDIDIELWSKEAPKACRNFIQLCLEAYYDNTIFHRVVPGFIVQGGDPTGTGSG 74 Query: 91 KKP--NPPIKNEADNGLR-NTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYA 147 + P K+E + LR N RG +AMA D+ SQFF + L++ + Sbjct: 75 GESIYGAPFKDEFHSRLRFNRRGLVAMANAGSHDNG-SQFFFTLGRADELNN-----KHT 128 Query: 148 VFGKVVKGMDVAD--KISQVPTHDVGPYQNVPSKPVVILSAKVL 189 +FGKV G V + ++S+V D P P I S +VL Sbjct: 129 IFGKVT-GDTVYNMLRLSEVDIDD----DERPHNPHKIKSCEVL 167 >2MVZ-A nrPDB Length = 148 Score = 80.9 bits (198), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 58/149 (38%), Positives = 73/149 (48%), Gaps = 31/149 (20%) Query: 21 AAMAAKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQ 80 +MA KG +L + G IE EL +APV+V NF N GFYN TFHRVIPGF+ Q Sbjct: 1 GSMAKKG---YILMENGGKIEFELFPNEAPVTVANFEKLANEGFYNGLTFHRVIPGFVSQ 57 Query: 81 GG----------GFTEQMQQKKPNPPIKNEADNG-LRNTRGTIAMARTADKDSATSQFFI 129 GG G+T I E DN R+ G ++MA +D+ + QFFI Sbjct: 58 GGCPRGNGTGDAGYT-----------IPCETDNNPHRHVTGAMSMAHRG-RDTGSCQFFI 105 Query: 130 NVADNAFLDHGQRDFGYAVFGKVVKGMDV 158 LD + VFG+V GMDV Sbjct: 106 VHEPQPHLDG-----VHTVFGQVTSGMDV 129 >1XWN-A nrPDB Length = 174 Score = 80.1 bits (196), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 54/160 (33%), Positives = 82/160 (51%), Gaps = 11/160 (6%) Query: 29 PHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQM 88 P+V L TS G I LEL + AP + +NF + G+YN T FHR+I FMIQGG T Sbjct: 12 PNVYLETSMGIIVLELYWKHAPKTCKNFAELARRGYYNGTKFHRIIKDFMIQGGDPTGTG 71 Query: 89 QQKKP--NPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGY 146 + ++E L+ T I A D+ SQFF+ +A +LD G+ + Sbjct: 72 RGGASIYGKQFEDELHPDLKFTGAGILAMANAGPDTNGSQFFVTLAPTQWLD-GK----H 126 Query: 147 AVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSA 186 +FG+V +G+ + +++ V T+ Q+ P V I+ A Sbjct: 127 TIFGRVCQGIGMVNRVGMVETNS----QDRPVDDVKIIKA 162 >2K7N-A nrPDB Length = 203 Score = 79.7 bits (195), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 57/161 (35%), Positives = 86/161 (53%), Gaps = 13/161 (8%) Query: 29 PHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQM 88 P+V L TS G I LEL + AP + +NF + G+YN T FHR+I FMIQGG T Sbjct: 12 PNVYLETSMGIIVLELYWKHAPKTCKNFAELARRGYYNGTKFHRIIKDFMIQGGDPTGTG 71 Query: 89 QQKKP--NPPIKNEADNGLRNT-RGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFG 145 + ++E L+ T G +AMA A D+ SQFF+ +A +LD G+ Sbjct: 72 RGGASIYGKQFEDELHPDLKFTGAGILAMA-NAGPDTNGSQFFVTLAPTQWLD-GK---- 125 Query: 146 YAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSA 186 + +FG+V +G+ + +++ V T+ Q+ P V I+ A Sbjct: 126 HTIFGRVCQGIGMVNRVGMVETNS----QDRPVDDVKIIKA 162 >3JB9-d nrPDB Length = 155 Score = 78.2 bits (191), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 53/161 (32%), Positives = 80/161 (49%), Gaps = 11/161 (6%) Query: 31 VLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQMQQ 90 V L TS G I +EL + AP + QNF G+Y+ FHRVIP F+IQGG T + Sbjct: 4 VELQTSLGKILIELYTEHAPKTCQNFYTLAKEGYYDGVIFHRVIPDFVIQGGDPTGTGRG 63 Query: 91 KKP--NPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAV 148 +E + L +T I A ++ +SQFFI +A +LD G+ + + Sbjct: 64 GTSIYGDKFDDEIHSDLHHTGAGILSMANAGPNTNSSQFFITLAPTPWLD-GK----HTI 118 Query: 149 FGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 FG+VV G+ V ++ + T + P +P+ I+ A L Sbjct: 119 FGRVVSGLSVCKRMGLIRTDS----SDRPIEPLKIIKAVAL 155 >2OK3-A nrPDB Length = 161 Score = 75.1 bits (183), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 51/162 (31%), Positives = 81/162 (50%), Gaps = 19/162 (11%) Query: 31 VLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFT----- 85 V L T G+I++E+ ++ P + +NF+ S +YN FHR I GFM+Q G T Sbjct: 3 VTLHTDVGDIKIEVFCERTPKTCENFLALCASNYYNGCIFHRNIKGFMVQTGDPTGTGRG 62 Query: 86 -EQMQQKKPNPPIKNEADNGLR-NTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRD 143 + KK ++E L+ N RG ++MA ++ SQFFI L D Sbjct: 63 GNSIWGKK----FEDEYSEYLKHNVRGVVSMANNG-PNTNGSQFFITYGKQPHL-----D 112 Query: 144 FGYAVFGKVVKGMDVADKISQVPTHD--VGPYQNVPSKPVVI 183 Y VFGKV+ G++ D++ ++P ++ P +V K + I Sbjct: 113 MKYTVFGKVIDGLETLDELEKLPVNEKTYRPLNDVHIKDITI 154 >1ZKC-A nrPDB Length = 197 Score = 70.9 bits (172), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 53/171 (30%), Positives = 82/171 (47%), Gaps = 12/171 (7%) Query: 22 AMAAKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQG 81 + +G +V L T+ G++ LEL P + +NF+ +Y+ T FHR I F+IQG Sbjct: 13 GLVPRGSGYVRLHTNKGDLNLELHCDLTPKTCENFIRLCKKHYYDGTIFHRSIRNFVIQG 72 Query: 82 GGFTEQMQQKKP--NPPIKNEADNGLRNT-RGTIAMARTADKDSATSQFFINVADNAFLD 138 G T + P K+E L +T RG ++MA + +S SQFFI A+LD Sbjct: 73 GDPTGTGTGGESYWGKPFKDEFRPNLSHTGRGILSMANSG-PNSNRSQFFITFRSCAYLD 131 Query: 139 HGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 + +FG+VV G DV + V + P + P + + I + V Sbjct: 132 K-----KHTIFGRVVGGFDVLTAMENVES---DPKTDRPKEEIRIDATTVF 174 >2B71-A nrPDB Length = 196 Score = 69.7 bits (169), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 46/140 (32%), Positives = 72/140 (51%), Gaps = 7/140 (5%) Query: 30 HVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQMQ 89 ++ + T+ G+ E+EL +P + NF GFY+NT FHRVIP F+IQGG T + Sbjct: 40 YITIYTNLGDFEVELYWYHSPKTCLNFYTLCEMGFYDNTIFHRVIPNFVIQGGDPTGTGK 99 Query: 90 QKKP--NPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYA 147 K ++E + L++T I ++ +SQFFI +A LD G+ + Sbjct: 100 GGKSIYGEYFEDEINKELKHTGAGILSMSNNGPNTNSSQFFITLAPLPHLD-GK----HT 154 Query: 148 VFGKVVKGMDVADKISQVPT 167 +F +V K M + I+ V T Sbjct: 155 IFARVSKNMTCIENIASVQT 174 >3K2C-A nrPDB Length = 193 Score = 68.2 bits (165), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 50/162 (30%), Positives = 79/162 (48%), Gaps = 29/162 (17%) Query: 20 PAAMAAKGDPHVLL-----TTSAGNIELELDKQKAPVSVQNF---VDYVNSGFYNNTTFH 71 P +MA + +V S G I ++L+ P + +NF + Y +TFH Sbjct: 19 PGSMAKEASGNVYFDVYANEESLGRIVMKLEDDIVPKTAKNFRTLCERPKGEGYKGSTFH 78 Query: 72 RVIPGFMIQGGGFTEQ--------MQQKKPNPPIKNEADNGLRNTR-GTIAMARTADKDS 122 R+IPGFM+QGG +T +K P+ + L++T+ G ++MA + Sbjct: 79 RIIPGFMVQGGDYTAHNGTGGRSIYGEKFPDENFE------LKHTKEGILSMANCGAHTN 132 Query: 123 ATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQ 164 SQFFI + +LD + VFG+VV+GMDV KI++ Sbjct: 133 G-SQFFITLGKTQWLDE-----KHVVFGEVVEGMDVVHKIAK 168 >2HAQ-A nrPDB Length = 172 Score = 67.4 bits (163), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 56/157 (35%), Positives = 82/157 (52%), Gaps = 15/157 (9%) Query: 38 GNIELELDKQKAPVSVQNFVDYVNS--GF-YNNTTFHRVIPGFMIQGGGFTEQMQQKKPN 94 G I + L + AP++ +NF GF Y ++ FHRVI FMIQGG FT + Sbjct: 26 GRITIGLFGKDAPLTTENFRQLCTGEHGFGYKDSIFHRVIQNFMIQGGDFTNFDGTGGKS 85 Query: 95 PPIKNEADNGL--RNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGKV 152 + AD L ++ G ++MA A ++ SQFFI A +LD G+ + VFGKV Sbjct: 86 IYGEKFADENLNVKHFVGALSMA-NAGPNTNGSQFFITTAPTPWLD-GR----HVVFGKV 139 Query: 153 VKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 + GMDV +I + T+ + P KPV I+++ L Sbjct: 140 LDGMDVVLRIEKTKTNS----HDRPVKPVKIVASGEL 172 >3ICH-A nrPDB Length = 188 Score = 65.1 bits (157), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 54/152 (35%), Positives = 74/152 (48%), Gaps = 16/152 (10%) Query: 38 GNIELELDKQKAPVSVQNFVDYV--NSGF-YNNTTFHRVIPGFMIQGGGFTEQMQQKKPN 94 G + L + P +V NFV GF Y N+ FHRVI FMIQGG FT + Sbjct: 30 GRVIFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKS 89 Query: 95 PPIKNEADNGLRNTR---GTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGK 151 + D + G ++MA A KD+ SQFFI A+LD G+ + VFGK Sbjct: 90 IYGERFPDENFKLKHYGPGWVSMA-NAGKDTNGSQFFITTVKTAWLD-GK----HVVFGK 143 Query: 152 VVKGMDVADKISQVPTHDVGPYQNVPSKPVVI 183 V++GM+V K+ T ++ P K V+I Sbjct: 144 VLEGMEVVRKVESTKTDS----RDKPLKDVII 171 >5EX2-A nrPDB Length = 271 Score = 65.1 bits (157), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 53/208 (25%), Positives = 85/208 (40%), Gaps = 63/208 (30%) Query: 28 DPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGG----- 82 D V+ T+ G + +EL + AP V V +G Y+ T FHRVI GFM QGG Sbjct: 23 DNLVIFETTKGVVYIELAPEIAPNHVAQIRKVVRTGLYSGTKFHRVISGFMAQGGDIAAT 82 Query: 83 ---------------------------------------GF-----TEQMQQKKPNPPIK 98 GF E Q + N Sbjct: 83 LGREPDLEAVDGEFVFRRDPKSIVLTVINEEDQTKSQYTGFYNGFPIETRQDELANYSED 142 Query: 99 NEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDV 158 ++ + + G ++MART D +S QFF+ ++ FLD Y+ +G++++G+DV Sbjct: 143 KRVESWMPHCAGVVSMARTNDPNSGKDQFFLMRDESRFLDR-----KYSSWGRMLEGLDV 197 Query: 159 ADKISQVPTHDVGPYQNVPSKPVVILSA 186 A ++ +G P +P +++SA Sbjct: 198 AKSLT------IG---EPPERPDILVSA 216 >4E1Q-A nrPDB Length = 207 Score = 64.7 bits (156), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 59/166 (35%), Positives = 78/166 (46%), Gaps = 24/166 (14%) Query: 37 AGNIELELDKQKAPVSVQNFVDYVN-------SG---FYNNTTFHRVIPGFMIQGGGFTE 86 AG I +EL K P +V+NF SG Y + FHRVIP FM QGG FT Sbjct: 53 AGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSAFHRVIPDFMCQGGDFTR 112 Query: 87 QMQQKKPNPPIKNEADNGL--RNTR-GTIAMARTADKDSATSQFFINVADNAFLDHGQRD 143 + + AD ++T+ G ++MA A ++ SQFFI +LD G+ Sbjct: 113 GNGTGGESIYGEKFADEKFVHKHTKPGILSMA-NAGPNTNGSQFFICTVPCNWLD-GK-- 168 Query: 144 FGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 + VFG+VV+GMDV I + VG SK VVI L Sbjct: 169 --HVVFGEVVEGMDVVKNIEK-----VGSRSGTCSKQVVIADCGQL 207 >6HIX-BQ nrPDB Length = 231 Score = 64.7 bits (156), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 47/149 (31%), Positives = 73/149 (48%), Gaps = 23/149 (15%) Query: 38 GNIELELDKQKAPVSVQNFVDYVNSG--------FYNNTTFHRVIPGFMIQGGGFTEQMQ 89 G + +EL P + +NF FY FHRVIPGF++QGG ++ Sbjct: 43 GRVSVELFHDIVPKTTENFRSLCTGERGYSQCPLFYKGIPFHRVIPGFIVQGGDIL--LK 100 Query: 90 QKKPNP-----PIKNEADNGL--RNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQR 142 + N P +E+ G ++ RGT+AMA +A + SQFF N+A N LD G+ Sbjct: 101 DGRGNVSVFGFPFPDESFEGKAGKHLRGTVAMAHSAPNQNG-SQFFFNLARNDHLD-GK- 157 Query: 143 DFGYAVFGKVVKGMDVADKISQVPTHDVG 171 + V G+V+ G +V D+++ + G Sbjct: 158 ---FVVCGQVIDGWEVVDRVAVLSGSSCG 183 >4HY7-A nrPDB Length = 171 Score = 64.3 bits (155), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 59/166 (35%), Positives = 78/166 (46%), Gaps = 24/166 (14%) Query: 37 AGNIELELDKQKAPVSVQNFVDYVN-------SG---FYNNTTFHRVIPGFMIQGGGFTE 86 AG I +EL K P +V+NF SG Y + FHRVIP FM QGG FT Sbjct: 17 AGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSAFHRVIPDFMCQGGDFTR 76 Query: 87 QMQQKKPNPPIKNEADNGL--RNTR-GTIAMARTADKDSATSQFFINVADNAFLDHGQRD 143 + + AD ++T+ G ++MA A ++ SQFFI +LD G+ Sbjct: 77 GNGTGGESIYGEKFADEKFVHKHTKPGILSMA-NAGPNTNGSQFFICTVPCNWLD-GK-- 132 Query: 144 FGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 + VFG+VV+GMDV I + VG SK VVI L Sbjct: 133 --HVVFGEVVEGMDVVKNIEK-----VGSRSGTCSKQVVIADCGQL 171 >4R3F-A nrPDB Length = 204 Score = 63.9 bits (154), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 49/187 (26%), Positives = 87/187 (46%), Gaps = 34/187 (18%) Query: 31 VLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQ--- 87 V++ T+ G++++EL ++ P++ +NF+ + G+Y+ T FHR++PGF+IQGG T Sbjct: 18 VIIHTTQGDLKVELFAKQTPLTCRNFLQHSLDGYYDGTIFHRLVPGFIIQGGDPTGTGHG 77 Query: 88 ------------------MQQKKPNPP------IKNEADNGLR-NTRGTIAMARTADKDS 122 M Q+K + K+E + L+ N RG + MA D+ Sbjct: 78 GESIYDGGAFSGDLDPWPMDQRKGHNAGPMGVNFKDEFHSRLKFNRRGLLGMANEGAPDT 137 Query: 123 ATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVV 182 SQFF + L++ +FG+V G D + + ++ P PV Sbjct: 138 NGSQFFFTLGKAEELNNKN-----TLFGRVAAG-DTIYNLMKWGEAELIEGTERPQYPVK 191 Query: 183 ILSAKVL 189 I + ++L Sbjct: 192 ITNIEIL 198 >4JJM-A nrPDB Length = 175 Score = 63.5 bits (153), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 57/166 (34%), Positives = 74/166 (44%), Gaps = 24/166 (14%) Query: 37 AGNIELELDKQKAPVSVQNFVDYVN-------SG---FYNNTTFHRVIPGFMIQGGGFTE 86 AG I +EL P + +NF SG Y ++FHRVIPGFM QGG FT Sbjct: 20 AGRIVMELFADVTPRTAENFRALCTGEKGIGKSGKPLHYKGSSFHRVIPGFMCQGGDFTA 79 Query: 87 QMQQKKPNPPIKNEADNGLRNTR---GTIAMARTADKDSATSQFFINVADNAFLDHGQRD 143 + AD G ++MA A + SQFF+ A +LD G+ Sbjct: 80 GNGTGGESIYGSKFADENFVKKHTGPGILSMA-NAGPGTNGSQFFVCTAKTEWLD-GK-- 135 Query: 144 FGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 + VFG+VV+GMDV I + VG +KPVVI L Sbjct: 136 --HVVFGQVVEGMDVVKAIEK-----VGSSSGRTNKPVVIADCGQL 174 >5EX1-A nrPDB Length = 283 Score = 63.5 bits (153), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 54/194 (27%), Positives = 84/194 (43%), Gaps = 45/194 (23%) Query: 31 VLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQMQQ 90 V++TT G+I +EL+ + AP V F D V + YN F+RVI GF+ QGG E Sbjct: 40 VVITTKYGDILIELNPEFAPGHVARFQDMVKARAYNGKEFYRVIDGFVAQGGIDAED--- 96 Query: 91 KKPNPPIKNEAD-------------------------NG-----------LRNTRGTIAM 114 K PP++ E + NG L + G +AM Sbjct: 97 -KKWPPLEIEHEQPLLEADQIQLLDNDDLFAEKVGFLNGFPVGFDAEKKWLLHCPGMLAM 155 Query: 115 ARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQ 174 AR +D ++ + F+I + +LD VFG+V+ GM K+ + + G Sbjct: 156 ARDSDPNTGGTDFYITLDAQRYLDR-----NMTVFGRVISGMQYVQKLQRGDKNIEGGVI 210 Query: 175 NVPSKPVVILSAKV 188 P+K ++S K+ Sbjct: 211 QSPNKGDEMISVKL 224 >3BO7-A nrPDB Length = 201 Score = 63.2 bits (152), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 44/157 (28%), Positives = 73/157 (46%), Gaps = 21/157 (13%) Query: 26 KGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFT 85 K ++ + T+ G++ +EL AP + +F+ ++++T FHR I FMIQGG Sbjct: 4 KKKGYLRIVTTQGSLNIELHADMAPRACDSFLRLCAVKYFDDTIFHRCIRNFMIQGGRAE 63 Query: 86 EQMQQKKPN--------------PPIKNEADNGL-RNTRGTIAMARTADKDSATSQFFIN 130 + KK P ++E DN L G ++MA K S S+FFI Sbjct: 64 LRQPSKKKEVQQSPRSISGFPGGAPFEDEFDNRLVHQGIGVLSMANDG-KHSNLSEFFIT 122 Query: 131 VADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPT 167 L++ + +FG+VV G+DV + ++ T Sbjct: 123 FKSCEHLNN-----KHTIFGRVVGGLDVLRQWEKLET 154 >5O9Z-M nrPDB Length = 177 Score = 62.8 bits (151), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 51/159 (32%), Positives = 71/159 (44%), Gaps = 21/159 (13%) Query: 36 SAGNIELELDKQKAPVSVQNFVDYVNSGF--------YNNTTFHRVIPGFMIQGGGFTEQ 87 G +++EL P + +NF + F Y +TFHRVI FMIQGG F Sbjct: 23 EVGRMKIELFADVVPKTAENFRQFCTGEFRKDGVPIGYKGSTFHRVIKDFMIQGGDFVNG 82 Query: 88 MQQKKPN---PPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDF 144 + P +E + G ++MA + + QFFI + +LD Sbjct: 83 DGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTNGC-QFFITCSKCDWLDG----- 136 Query: 145 GYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVI 183 + VFGK++ G+ V KI VPT GP N P PVVI Sbjct: 137 KHVVFGKIIDGLLVMRKIENVPT---GP-NNKPKLPVVI 171 >5MQF-o nrPDB Length = 301 Score = 62.8 bits (151), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 52/169 (30%), Positives = 81/169 (47%), Gaps = 17/169 (10%) Query: 19 SPAAMAAKGDPHVLLTTSAGN-----IELELDKQKAPVSVQNFVDYV--NSGF-YNNTTF 70 P A A+ +P V + GN I++ L P++ +NF GF + ++F Sbjct: 130 EPIAKKARSNPQVYMDIKIGNKPAGRIQMLLRSDVVPMTAENFRCLCTHEKGFGFKGSSF 189 Query: 71 HRVIPGFMIQGGGFTEQMQQKKPNPPIKNEADNG--LRNTR-GTIAMARTADKDSATSQF 127 HR+IP FM QGG FT + K D L++T G ++MA + ++ SQF Sbjct: 190 HRIIPQFMCQGGDFTNHNGTGGKSIYGKKFDDENFILKHTGPGLLSMANSG-PNTNGSQF 248 Query: 128 FINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNV 176 F+ +LD G+ + VFG+V +G+DV +I + D P Q V Sbjct: 249 FLTCDKTDWLD-GK----HVVFGEVTEGLDVLRQIEAQGSKDGKPKQKV 292 >2QER-A nrPDB Length = 185 Score = 62.4 bits (150), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 50/165 (30%), Positives = 80/165 (48%), Gaps = 18/165 (10%) Query: 31 VLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFT----- 85 V + T+ G+++ EL + P + +NF+ SG+Y NT FH+ I GF+IQGG T Sbjct: 19 VRIITNYGDLKFELFCSQCPKACKNFLALSASGYYKNTIFHKNIKGFIIQGGDPTGTGKG 78 Query: 86 -EQMQQKKPNPPIKNEADNGLRNTRGTIAMA-RTADKDSAT--SQFFINVADNAFLDHGQ 141 E + + + I E + RG ++MA + A K T SQFFI + Q Sbjct: 79 GESIYGRYFDDEIYPELK---YDRRGILSMASKGASKKPNTNGSQFFITYSSLP-----Q 130 Query: 142 RDFGYAVFGKVVKGMDVADKISQVPTHDV-GPYQNVPSKPVVILS 185 + Y +FGK++ G + + + P+ P + K +VI S Sbjct: 131 LNGEYVIFGKLIDGFETLNTLENCPSDKSHKPIDEIIIKDIVIHS 175 >2MC9-A nrPDB Length = 178 Score = 62.4 bits (150), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 54/156 (34%), Positives = 72/156 (46%), Gaps = 24/156 (15%) Query: 28 DPHVLLTTS-----AGNIELELDKQKAPVSVQNFVDYV-------NSG---FYNNTTFHR 72 +P V S AG I +EL P + +NF SG Y +++FHR Sbjct: 9 NPRVFFDMSVGGQPAGRIVMELFADTTPRTAENFRALCTGEKGTGRSGKPLHYKDSSFHR 68 Query: 73 VIPGFMIQGGGFTEQMQQKKPNPPIKNEADNGLRNTR---GTIAMARTADKDSATSQFFI 129 VIPGFM QGG FT + AD G ++MA A ++ SQFFI Sbjct: 69 VIPGFMCQGGDFTAGNGTGGESIYGAKFADENFIKKHTGPGILSMA-NAGPNTNGSQFFI 127 Query: 130 NVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQV 165 A +LD G+ + VFG+VV+GMDV I +V Sbjct: 128 CTAKTEWLD-GK----HVVFGQVVEGMDVVKAIEKV 158 >4EYV-A nrPDB Length = 167 Score = 62.4 bits (150), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 53/157 (33%), Positives = 79/157 (50%), Gaps = 17/157 (10%) Query: 36 SAGNIELELDKQKAPVSVQNFVDYVNS---GFYNNTTFHRVIPGFMIQGGGFTEQMQQKK 92 +AG I +L P++ +NF + + Y +TFHR+IP FM+QGG FT Sbjct: 19 NAGRIVFKLYDDVVPLTAKNFRELAKNPAGQGYTGSTFHRIIPQFMLQGGDFTNHNGTGG 78 Query: 93 PNPPIKNEADNG--LRNTR-GTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVF 149 + D L++T+ G ++MA A + SQFFI ++LD G+ + VF Sbjct: 79 RSIYGNKFKDENFQLKHTKPGLLSMAN-AGPHTNGSQFFITTVVTSWLD-GK----HVVF 132 Query: 150 GKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSA 186 G+VV+GMDV K+ VG PSK V I ++ Sbjct: 133 GEVVEGMDVVKKVEA-----VGTQSGKPSKVVKITAS 164 >3UCH-A nrPDB Length = 174 Score = 62.0 bits (149), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 52/169 (30%), Positives = 81/169 (47%), Gaps = 17/169 (10%) Query: 19 SPAAMAAKGDPHVLLTTSAGN-----IELELDKQKAPVSVQNFVDYV--NSGF-YNNTTF 70 P A A+ +P V + GN I++ L P++ +NF GF + ++F Sbjct: 3 EPIAKKARSNPQVYMDIKIGNKPAGRIQMLLRSDVVPMTAENFRCLCTHEKGFGFKGSSF 62 Query: 71 HRVIPGFMIQGGGFTEQMQQKKPNPPIKNEADNG--LRNTR-GTIAMARTADKDSATSQF 127 HR+IP FM QGG FT + K D L++T G ++MA + ++ SQF Sbjct: 63 HRIIPQFMCQGGDFTNHNGTGGKSIYGKKFDDENFILKHTGPGLLSMANSG-PNTNGSQF 121 Query: 128 FINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNV 176 F+ +LD G+ + VFG+V +G+DV +I + D P Q V Sbjct: 122 FLTCDKTDWLD-GK----HVVFGEVTEGLDVLRQIEAQGSKDGKPKQKV 165 >3RDD-A nrPDB Length = 184 Score = 62.0 bits (149), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 49/138 (35%), Positives = 73/138 (52%), Gaps = 12/138 (8%) Query: 38 GNIELELDKQKAPVSVQNF--VDYVNSGF-YNNTTFHRVIPGFMIQGGGFTEQ-MQQKKP 93 G + EL K P + +NF + GF Y + FHR+IPGFM QGG FT K Sbjct: 37 GRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKS 96 Query: 94 NPPIKNEADNG-LRNTR-GTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGK 151 K E +N L++T G ++MA A ++ SQFFI A +LD G+ + VFGK Sbjct: 97 IYGEKFEDENFILKHTGPGILSMA-NAGPNTNGSQFFICTAKTEWLD-GK----HVVFGK 150 Query: 152 VVKGMDVADKISQVPTHD 169 V +GM++ + + + + + Sbjct: 151 VKEGMNIVEAMERFGSRN 168 >5TA2-A nrPDB Length = 163 Score = 62.0 bits (149), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 49/138 (35%), Positives = 73/138 (52%), Gaps = 12/138 (8%) Query: 38 GNIELELDKQKAPVSVQNF--VDYVNSGF-YNNTTFHRVIPGFMIQGGGFTEQ-MQQKKP 93 G + EL K P + +NF + GF Y + FHR+IPGFM QGG FT K Sbjct: 17 GRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKS 76 Query: 94 NPPIKNEADNG-LRNTR-GTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGK 151 K E +N L++T G ++MA A ++ SQFFI A +LD G+ + VFGK Sbjct: 77 IYGEKFEDENFILKHTGPGILSMA-NAGPNTNGSQFFICTAKTEWLD-GK----HVVFGK 130 Query: 152 VVKGMDVADKISQVPTHD 169 V +GM++ + + + + + Sbjct: 131 VKEGMNIVEAMERFGSRN 148 >2HQJ-A nrPDB Length = 183 Score = 61.2 bits (147), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 50/146 (34%), Positives = 75/146 (51%), Gaps = 22/146 (15%) Query: 36 SAGNIELELDKQKAPVSVQNFVDYV-------NSG---FYNNTTFHRVIPGFMIQGGGFT 85 +AG I +EL P + +NF SG Y ++ FHRVIP FMIQGG FT Sbjct: 20 AAGRIVMELYADTVPKTAENFRALCTGEKGKGRSGKPLHYKSSVFHRVIPNFMIQGGDFT 79 Query: 86 E---QMQQKKPNPPIKNEADNGL--RNTR-GTIAMARTADKDSATSQFFINVADNAFLDH 139 + ++E+ +G R+T G ++MA A ++ SQFFI A +LD Sbjct: 80 RGNGTGGESIYGTTFRDESFSGKAGRHTGLGCLSMA-NAGPNTNGSQFFICTAATPWLD- 137 Query: 140 GQRDFGYAVFGKVVKGMDVADKISQV 165 G+ + VFG+V+ G+DV K+ ++ Sbjct: 138 GK----HVVFGRVIDGLDVVKKVERL 159 >1XQ7-A nrPDB Length = 166 Score = 60.8 bits (146), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 54/158 (34%), Positives = 78/158 (49%), Gaps = 15/158 (9%) Query: 37 AGNIELELDKQKAPVSVQNFVDYVN--SGF-YNNTTFHRVIPGFMIQGGGFT--EQMQQK 91 G + + L P +V+NF + +GF Y + FHRVI FMIQGG FT + K Sbjct: 19 VGRVVIGLFGNDVPKTVENFKQLASGENGFGYKGSIFHRVIRNFMIQGGDFTNFDGTGGK 78 Query: 92 KPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGK 151 ++ + +++ G ++MA A +S SQFF+ A +LD G+ + VFGK Sbjct: 79 SIYGTRFDDENLKIKHFVGAVSMA-NAGPNSNGSQFFVTTAPTPWLD-GR----HVVFGK 132 Query: 152 VVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 VV+GMDV K+ T + P K V I VL Sbjct: 133 VVEGMDVVKKVENTKTG----LNDKPKKAVKINDCGVL 166 >2POY-A nrPDB Length = 186 Score = 60.5 bits (145), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 55/171 (32%), Positives = 79/171 (46%), Gaps = 32/171 (18%) Query: 35 TSAGNIELELDKQKAPVSVQNFVDYVN-------SG---FYNNTTFHRVIPGFMIQGGGF 84 T AG I +EL K P++ +NF SG Y + FHR+IP FMIQGG F Sbjct: 31 TPAGRITMELFADKVPITAENFRALCTGEKGMGQSGKPLCYTGSFFHRIIPQFMIQGGDF 90 Query: 85 T-------EQMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFL 137 T E + K ++E + ++MA A ++ SQFFI +L Sbjct: 91 TRGDGTGGESIYGSK----FRDENFVYTHDAPFLLSMAN-AGPNTNGSQFFITTVPCPWL 145 Query: 138 DHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKV 188 D G+ + VFGKV++GM+V I + G P+K V I ++ V Sbjct: 146 D-GK----HVVFGKVLEGMEVVKSIEK-----CGSQNGKPTKSVCITASGV 186 >2FU0-A nrPDB Length = 160 Score = 60.5 bits (145), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 44/159 (27%), Positives = 78/159 (49%), Gaps = 11/159 (6%) Query: 32 LLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQMQ-- 89 ++ T+ G+I + L ++ +VQNF + +G+YNN FHRVI FM+Q G + Sbjct: 9 IIYTTMGDIHISLFYKECKKTVQNFSVHSINGYYNNCIFHRVIKHFMVQTGDPSGDGTGG 68 Query: 90 QKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVF 149 + ++E + L +++ + ++ SQFFI +L DF + VF Sbjct: 69 ESIWGNEFEDEFFDHLNHSKPFMVSMANCGPNTNGSQFFITTVPCPWL-----DFKHTVF 123 Query: 150 GKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKV 188 GKV +G + I +V T ++ P + + IL+ K+ Sbjct: 124 GKVTQGSKIVLDIEKVRTDK----RDKPLEDIKILNIKI 158 >3PMP-A nrPDB Length = 164 Score = 60.1 bits (144), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 44/132 (33%), Positives = 72/132 (54%), Gaps = 12/132 (9%) Query: 38 GNIELELDKQKAPVSVQNFVDYVNS--GF-YNNTTFHRVIPGFMIQGGGFTEQMQQKKPN 94 G I +L + P + +NF + GF Y ++ FHRVIP FM+QGG FT + Sbjct: 17 GRIVFKLYDEAVPKTAKNFRELATGQHGFGYKDSIFHRVIPQFMLQGGDFTRHNGTGGKS 76 Query: 95 PPIKNEADNG--LRNTR-GTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGK 151 + AD +++T+ G ++MA A ++ SQFFI ++LD G+ + VFG+ Sbjct: 77 IYGEKFADENFQVKHTKPGLLSMA-NAGANTNGSQFFITTVPTSWLD-GK----HVVFGE 130 Query: 152 VVKGMDVADKIS 163 V++G+D+ K+ Sbjct: 131 VIEGLDIVRKVE 142 >3R49-A nrPDB Length = 166 Score = 59.3 bits (142), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 57/174 (32%), Positives = 73/174 (41%), Gaps = 22/174 (12%) Query: 27 GDPHVLLTTSA-----GNIELELDKQKAPVSVQNFVDYVNS--GF-YNNTTFHRVIPGFM 78 G+P V L A G + LEL P + +NF GF Y +TFHRVIP FM Sbjct: 3 GNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPSFM 62 Query: 79 IQGGGFTEQMQQKKPNPPIKNEADNGLRNTR---GTIAMARTADKDSATSQFFINVADNA 135 Q G FT + D G ++MA A ++ SQFFI Sbjct: 63 CQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMA-NAGPNTNGSQFFICTIKTD 121 Query: 136 FLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 +LD G+ + VFG V++GMDV KI G SK +VI L Sbjct: 122 WLD-GK----HVVFGHVIEGMDVVKKIES-----FGSKSGRTSKKIVITDCGQL 165 >1H0P-A nrPDB Length = 182 Score = 58.5 bits (140), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 46/133 (34%), Positives = 64/133 (48%), Gaps = 12/133 (9%) Query: 38 GNIELELDKQKAPVSVQNFVDYVN---SGFYNNTTFHRVIPGFMIQGGGFTEQMQQKKPN 94 G I + L + P + NF++ Y + FHRVI FMIQGG FT + Sbjct: 21 GRIVIGLFGKTVPKTATNFIELAKKPKGEGYPGSKFHRVIADFMIQGGDFTRGDGTGGRS 80 Query: 95 PPIKNEADNGLRNTR---GTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGK 151 + AD + G ++MA A D+ SQFFI +LD G+ + VFGK Sbjct: 81 IYGEKFADENFKLKHYGAGWLSMA-NAGADTNGSQFFITTVKTPWLD-GR----HVVFGK 134 Query: 152 VVKGMDVADKISQ 164 +++GMDV KI Q Sbjct: 135 ILEGMDVVRKIEQ 147 >6HMZ-X nrPDB Length = 180 Score = 58.2 bits (139), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 55/174 (31%), Positives = 72/174 (41%), Gaps = 52/174 (29%) Query: 37 AGNIELELDKQKAPVSVQNFVDYVNSG----------FYNNTTFHRVIPGFMIQGGGFT- 85 AG + +EL P + NF Y + FHR+IPGFM QGG FT Sbjct: 17 AGRVVMELFADVTPRTADNFRALCTGEKGIGQAGKALHYKGSAFHRIIPGFMCQGGDFTR 76 Query: 86 ----------------EQMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFI 129 E + K P I + A++G NT G SQFFI Sbjct: 77 GNGTGGESIYGAKFQDENFKLKHTGPGILSMANSG-PNTNG--------------SQFFI 121 Query: 130 NVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVI 183 A+LD G+ + VFGKVV G +V + + VG + V S+PVVI Sbjct: 122 CTDKTAWLD-GK----HVVFGKVVDGYNVVKAMEK-----VGSERGVTSEPVVI 165 >5YB9-A nrPDB Length = 175 Score = 57.8 bits (138), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 49/156 (31%), Positives = 68/156 (43%), Gaps = 35/156 (22%) Query: 38 GNIELELDKQKAPVSVQNFVDYVN-------SGF---YNNTTFHRVIPGFMIQGGGFTE- 86 G I EL P + +NF SG Y T FHR+IP FMIQGG FT Sbjct: 21 GKIVFELFNDIVPKTAENFRALCTGEKGIGKSGMPLSYKGTMFHRIIPQFMIQGGDFTRF 80 Query: 87 ---------QMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFL 137 M+ N +K++ G ++MA A ++ SQFFI + +L Sbjct: 81 NGTGGESIYGMKFDDENFKVKHDKP-------GLLSMA-NAGPNTNGSQFFITTVETPWL 132 Query: 138 D-HGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGP 172 D H + VFG+V++GMD+ +I T P Sbjct: 133 DGH------HCVFGQVIEGMDIVKQIESCGTESGRP 162 >3BKP-A nrPDB Length = 232 Score = 57.0 bits (136), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 23/52 (44%), Positives = 37/52 (71%) Query: 31 VLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGG 82 V+L TS G++++EL ++ P++ +NFV G+Y NT FHRV+ F++QGG Sbjct: 24 VVLHTSLGDLDVELWARECPLACRNFVQLCLEGYYVNTIFHRVVKDFIVQGG 75 >2CMT-A nrPDB Length = 172 Score = 56.6 bits (135), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 51/160 (31%), Positives = 74/160 (46%), Gaps = 31/160 (19%) Query: 37 AGNIELELDKQKAPVSVQNFVDYV--NSGF-YNNTTFHRVIPGFMIQGGGFT-------E 86 AG I +EL P + +NF GF Y+N FHRVIP FM QGG F + Sbjct: 24 AGRIVMELRSDIVPRTAENFRALCTGERGFGYHNCCFHRVIPQFMCQGGDFVKGDGTGGK 83 Query: 87 QMQQKK---PNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRD 143 + +K N +++E G ++MA + ++ SQFFI +LD G+ Sbjct: 84 SIYGRKFDDENFQLRHEG-------FGVLSMANSG-PNTNGSQFFICTTKCDWLD-GK-- 132 Query: 144 FGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVI 183 + VFG+VV G +V K+ VG +PV+I Sbjct: 133 --HVVFGRVVDGQNVVKKMES-----VGSKSGKVKEPVII 165 >4JCP-A nrPDB Length = 175 Score = 56.2 bits (134), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 49/155 (31%), Positives = 68/155 (43%), Gaps = 47/155 (30%) Query: 35 TSAGNIELELDKQKAPVSVQNFVDYV-------NSG---FYNNTTFHRVIPGFMIQGGGF 84 ++AG I +EL P + +NF SG Y + FHRVIP FM+QGG F Sbjct: 19 SNAGRIVMELFADIVPKTAENFRCLCTGERGMGRSGKKLHYKGSKFHRVIPNFMLQGGDF 78 Query: 85 T-----------------EQMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQF 127 T E Q+K P G ++MA A ++ SQF Sbjct: 79 TRGNGTGGESIYGEKFPDENFQEKHTGP--------------GVLSMA-NAGPNTNGSQF 123 Query: 128 FINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKI 162 FI A +LD G+ + VFG+VV+GM+V + Sbjct: 124 FICTAKTEWLD-GK----HVVFGRVVEGMNVVKAV 153 >1C5F-A nrPDB Length = 177 Score = 54.7 bits (130), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 58/181 (32%), Positives = 74/181 (40%), Gaps = 52/181 (28%) Query: 37 AGNIELELDKQKAPVSVQNFVDYVN--------SG---FYNNTTFHRVIPGFMIQGGGFT 85 AG I +EL AP + NF+ SG Y +TFHRVI FMIQGG FT Sbjct: 20 AGRIVMELYNDIAPRTCNNFLMLCTGMAGTGKISGKPLHYKGSTFHRVIKNFMIQGGDFT 79 Query: 86 -----------------EQMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFF 128 E+ K P + + A+ G NT G SQFF Sbjct: 80 KGDGTGGESIYGGMFDDEEFVMKHDEPFVVSMANKG-PNTNG--------------SQFF 124 Query: 129 INVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKV 188 I L++ + VFGKVV G +V KI + T+ +N P VVIL+ Sbjct: 125 ITTTPAPHLNN-----IHVVFGKVVSGQEVVTKIEYLKTNS----KNRPLADVVILNCGE 175 Query: 189 L 189 L Sbjct: 176 L 176 >6HIX-BZ nrPDB Length = 190 Score = 53.1 bits (126), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 51/184 (27%), Positives = 75/184 (40%), Gaps = 37/184 (20%) Query: 34 TTSAGNIELELDKQKAPVSVQNFVDYVNSGF-----------------------YNNTTF 70 T + I +L +K P +V+NF++ + Y N+TF Sbjct: 15 TKAPRRIVFKLFPRKCPSAVKNFIELCSGNVSTDTYESGNRDKLISESALPQLTYKNSTF 74 Query: 71 HRVIPGFMIQGGGF-----TEQMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATS 125 HRV G++IQGG TEQ+ E + + G + A ++ ++ S Sbjct: 75 HRVEKGYLIQGGDIVTGRGTEQLSIYGGTFSAPEEVRASVFDKPGLVGTA-SSSPNAHGS 133 Query: 126 QFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILS 185 QFFI A A +G FG+V G+DV +I QVP G PS V I+ Sbjct: 134 QFFILTAKEANHLNGT----CICFGQVADGLDVVQEIEQVPIDPSG----FPSLKVSIVD 185 Query: 186 AKVL 189 VL Sbjct: 186 CGVL 189 >2RMC-A nrPDB Length = 182 Score = 52.4 bits (124), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 46/133 (34%), Positives = 63/133 (47%), Gaps = 12/133 (9%) Query: 37 AGNIELELDKQKAPVSVQNFVDYVNS--GF-YNNTTFHRVIPGFMIQGGGFTEQMQQKKP 93 G I + L P +V+NFV G+ Y + FHRVI FMIQGG FT + Sbjct: 21 VGRIVIGLFGNVVPKTVENFVALATGEKGYGYKGSIFHRVIKDFMIQGGDFTARDGTGGM 80 Query: 94 NPPIKNEADNGLRNTR---GTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFG 150 + + D + G ++MA A D+ SQFFI + +LD G+ + VFG Sbjct: 81 SIYGETFPDENFKLKHYGIGWVSMAN-AGPDTNGSQFFITLTKPTWLD-GK----HVVFG 134 Query: 151 KVVKGMDVADKIS 163 KV+ GM V I Sbjct: 135 KVLDGMTVVHSIE 147 >2CFE-A nrPDB Length = 162 Score = 52.4 bits (124), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 45/131 (34%), Positives = 63/131 (48%), Gaps = 12/131 (9%) Query: 38 GNIELELDKQKAPVSVQNFVDYVNS--GF-YNNTTFHRVIPGFMIQGGGFTEQMQQKKPN 94 G I+ +L P + NF GF Y + FHRVIP FM+QGG FT + Sbjct: 16 GTIKFKLFDDVVPKTAANFRALCTGEKGFGYAGSHFHRVIPDFMLQGGDFTAGNGTGGKS 75 Query: 95 PPIKNEADNGLR---NTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGK 151 AD + N G ++MA A ++ SQFFI ++LD G+ + VFG+ Sbjct: 76 IYGAKFADENFQLKHNKPGLLSMAN-AGPNTNGSQFFITTVVTSWLD-GK----HVVFGE 129 Query: 152 VVKGMDVADKI 162 V+ GM+V I Sbjct: 130 VIDGMNVVKAI 140 >1IST-A nrPDB Length = 162 Score = 51.6 bits (122), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 45/139 (32%), Positives = 63/139 (45%), Gaps = 22/139 (15%) Query: 38 GNIELELDKQKAPVSVQNFVDYVNS--GF-YNNTTFHRVIPGFMIQGGGFTEQ------- 87 G + +L P + +NF GF Y + FHRVIP FM+QGG FT Sbjct: 16 GRVVFKLYNDIVPKTAENFRALCTGEKGFGYAGSPFHRVIPDFMLQGGDFTAGNGTGGKS 75 Query: 88 -MQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGY 146 K P+ K D G ++MA A ++ SQFFI +LD G+ + Sbjct: 76 IYGGKFPDENFKKHHDR-----PGLLSMA-NAGPNTNGSQFFITTVPCPWLD-GK----H 124 Query: 147 AVFGKVVKGMDVADKISQV 165 VFG+VV G D+ K+ + Sbjct: 125 VVFGEVVDGYDIVKKVESL 143 >1QNH-A nrPDB Length = 170 Score = 51.2 bits (121), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 42/142 (29%), Positives = 66/142 (46%), Gaps = 18/142 (12%) Query: 35 TSAGNIELELDKQKAPVSVQNFVDYVNSG---------FYNNTTFHRVIPGFMIQGGGFT 85 ++AG I EL P + +NF Y N+ FHR+IP FM QGG T Sbjct: 15 SNAGRIIFELFSDITPRTCENFRALCTGEKIGSRGKNLHYKNSIFHRIIPQFMCQGGDIT 74 Query: 86 E---QMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQR 142 + +E N + G ++MA A ++ +SQF I + +LD G+ Sbjct: 75 NGNGSGGESIYGRSFTDENFNMKHDQPGLLSMA-NAGPNTNSSQFLITLVPCPWLD-GK- 131 Query: 143 DFGYAVFGKVVKGMDVADKISQ 164 + VFGKV++GM+V ++ + Sbjct: 132 ---HVVFGKVIEGMNVVREMEK 150 >2C3B-A nrPDB Length = 172 Score = 50.8 bits (120), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 46/151 (30%), Positives = 67/151 (44%), Gaps = 21/151 (13%) Query: 8 AMAAVFALSALSPAAMAAKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVN---SGF 64 +M+ VF +P A T G I L + P + +NF + Sbjct: 1 SMSQVFFDVEYAPVGTAE---------TKVGRIVFNLFDKDVPKTAKNFRELCKRPAGEG 51 Query: 65 YNNTTFHRVIPGFMIQGGGFTEQMQQKKPNPPIKNEADNGL---RNTRGTIAMARTADKD 121 Y +TFHR+IP FMIQGG FT + AD + +G ++MA A + Sbjct: 52 YRESTFHRIIPNFMIQGGDFTRGNGTGGRSIYGDKFADENFSRKHDKKGILSMA-NAGPN 110 Query: 122 SATSQFFINVADNAFLDHGQRDFGYAVFGKV 152 + SQFFI A ++LD G+ + VFG+V Sbjct: 111 TNGSQFFITTAVTSWLD-GK----HVVFGEV 136 >1E8K-A nrPDB Length = 173 Score = 50.4 bits (119), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 45/159 (28%), Positives = 70/159 (44%), Gaps = 29/159 (18%) Query: 36 SAGNIELELDKQKAPVSVQNFVDYV-------NSG---FYNNTTFHRVIPGFMIQGGGFT 85 ++G I +EL P + NF SG + + FHR+IP FMIQGG FT Sbjct: 16 ASGRIVMELYDDVVPKTAGNFRALCTGENGIGKSGKPLHFKGSKFHRIIPNFMIQGGDFT 75 Query: 86 EQ--------MQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFL 137 +K P+ K + G ++MA A ++ SQFF+ +L Sbjct: 76 RGNGTGGESIYGEKFPDENFKEK-----HTGPGVLSMA-NAGPNTNGSQFFLCTVKTEWL 129 Query: 138 DHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNV 176 D G+ + VFG+VV+G+DV + + P ++ Sbjct: 130 D-GK----HVVFGRVVEGLDVVKAVESNGSQSGKPVKDC 163 >2ESL-A nrPDB Length = 190 Score = 50.4 bits (119), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 48/140 (34%), Positives = 65/140 (46%), Gaps = 14/140 (10%) Query: 38 GNIELELDKQKAPVSVQNFVDYVNS--GF-YNNTTFHRVIPGFMIQGGGFTEQMQQKKPN 94 G I + L + P +V+NFV G+ Y + FHRVI FMIQGG T + Sbjct: 30 GRIVIGLFGKVVPKTVENFVALATGEKGYGYKGSKFHRVIKDFMIQGGDITTGDGTGGVS 89 Query: 95 PPIKNEADNGLRNTR---GTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGK 151 + D + G ++MA A D+ SQFFI + +LD G+ + VFGK Sbjct: 90 IYGETFPDENFKLKHYGIGWVSMAN-AGPDTNGSQFFITLTKPTWLD-GK----HVVFGK 143 Query: 152 VVKGMDVADKISQVPT--HD 169 V+ GM V I T HD Sbjct: 144 VIDGMTVVHSIELQATDGHD 163 >4I9Y-A nrPDB Length = 167 Score = 49.7 bits (117), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 45/147 (30%), Positives = 64/147 (43%), Gaps = 19/147 (12%) Query: 23 MAAKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYV--NSGF-YNNTTFHRVIPGFMI 79 + A G+P G I +EL P + +NF GF + N+ FHRVIP F+ Sbjct: 13 VCADGEP-------LGRITMELFSNIVPRTAENFRALCTGEKGFGFKNSIFHRVIPDFVC 65 Query: 80 QGGGFTEQ---MQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAF 136 QGG T+ Q ++E + G ++MA +++ SQF I + Sbjct: 66 QGGDITKHDGTGGQSIYGDKFEDENFDVKHTGPGLLSMANQG-QNTNNSQFVITLKKAEH 124 Query: 137 LDHGQRDFGYAVFGKVVKGMDVADKIS 163 L DF + VFG V GMD KI Sbjct: 125 L-----DFKHVVFGFVKDGMDTVKKIE 146 >1W74-A nrPDB Length = 191 Score = 49.3 bits (116), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 58/189 (30%), Positives = 80/189 (42%), Gaps = 59/189 (31%) Query: 33 LTTSAGNIELELDKQKAPVSVQNFV-------DYVN-------SG-FYNNTTFHRVIPGF 77 L T+ G+I++ L AP +V NFV DY SG FY+ FHRVI GF Sbjct: 28 LHTNRGDIKIALFGNHAPKTVANFVGLAQGTKDYSTQNASGGPSGPFYDGAVFHRVIQGF 87 Query: 78 MIQGGG----------------FTEQMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKD 121 MIQGG F ++Q KP +AMA A Sbjct: 88 MIQGGDPTGTGRGGPGYKFADEFHPELQFDKPY----------------LLAMAN-AGPG 130 Query: 122 SATSQFFINVADNAFLDHGQRDFGYAVFGKVV--KGMDVADKISQVPTHDVGPYQNVPSK 179 + SQFFI V L+ +R + +FG+V+ + V + IS+ T + P+ Sbjct: 131 TNGSQFFITVGKTPHLN--RR---HTIFGEVIDAESQRVVEAISKTATDG----NDRPTD 181 Query: 180 PVVILSAKV 188 PVVI S + Sbjct: 182 PVVIESITI 190 >2HE9-A nrPDB Length = 192 Score = 48.5 bits (114), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 47/166 (28%), Positives = 72/166 (43%), Gaps = 23/166 (13%) Query: 38 GNIELELDKQKAPVSVQNFVDYVNSG------------FYNNTTFHRVIPGFMIQGGGFT 85 G I +L P + +NF+ + SG Y +TFHRV+ FMIQGG F+ Sbjct: 34 GRIMFQLFSDICPKTCKNFL-CLCSGEKGLGKTTGKKLCYKGSTFHRVVKNFMIQGGDFS 92 Query: 86 E---QMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQR 142 E + + K+E + L++ R + K + SQFFI LD Sbjct: 93 EGNGKGGESIYGGYFKDE-NFILKHDRAFLLSMANRGKHTNGSQFFITTKPAPHLDG--- 148 Query: 143 DFGYAVFGKVVKGMDVADKISQVPTHDVG-PYQNVPSKPVVILSAK 187 + VFG V+ G +V ++I + T PY +V +L+ K Sbjct: 149 --VHVVFGLVISGFEVIEQIENLKTDAASRPYADVRVIDCGVLATK 192 >1IHG-A nrPDB Length = 370 Score = 48.1 bits (113), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 43/149 (28%), Positives = 61/149 (40%), Gaps = 20/149 (13%) Query: 38 GNIELELDKQKAPVSVQNFVDYVNSG-----------FYNNTTFHRVIPGFMIQGGGFTE 86 G I LEL P + +NF + FHR+I FMIQGG F+ Sbjct: 30 GRIVLELFADIVPKTAENFRALCTGEKGIGPTTGKPLHFKGCPFHRIIKKFMIQGGDFSN 89 Query: 87 QM---QQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRD 143 Q + ++E + + G ++MA A ++ SQFFI LD Sbjct: 90 QNGTGGESIYGEKFEDENFHYKHDKEGLLSMA-NAGSNTNGSQFFITTVPTPHLDG---- 144 Query: 144 FGYAVFGKVVKGMDVADKISQVPTHDVGP 172 + VFG+V+KGM VA + V P Sbjct: 145 -KHVVFGQVIKGMGVAKILENVEVKGEKP 172 >2WFI-A nrPDB Length = 179 Score = 47.8 bits (112), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 49/171 (28%), Positives = 70/171 (40%), Gaps = 32/171 (18%) Query: 37 AGNIELELDKQKAPVSVQNFVDYVNSG-----------FYNNTTFHRVIPGFMIQGGGFT 85 AG + EL P + +NF Y + FHRV+ FM+QGG F+ Sbjct: 23 AGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFS 82 Query: 86 E---QMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLD-HGQ 141 E + + ++E+ N ++MA KD+ SQFFI LD H Sbjct: 83 EGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRG-KDTNGSQFFITTKPTPHLDGH-- 139 Query: 142 RDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKP---VVILSAKVL 189 + VFG+V+ G +V +I T + SKP V ILS L Sbjct: 140 ----HVVFGQVISGQEVVREIENQKT-------DAASKPFAEVRILSCGEL 179 >1Z81-A nrPDB Length = 229 Score = 47.4 bits (111), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 44/178 (24%), Positives = 72/178 (40%), Gaps = 23/178 (12%) Query: 28 DPHVLLTTSAGN-----IELELDKQKAPVSVQNFVDYVNSGF--------YNNTTFHRVI 74 +P V + + GN + EL + P + +NF + + Y NT FHRVI Sbjct: 59 NPVVFMDINLGNNFLGKFKFELFQNIVPKTSENFRQFCTGEYKVNNLPVGYKNTIFHRVI 118 Query: 75 PGFMIQGGGFTEQMQQKKPN---PPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINV 131 FMIQGG F + +E + + G ++MA + ++ QFFI Sbjct: 119 KEFMIQGGDFINHNGSGSLSIYGEKFDDENFDIKHDKEGLLSMANSG-PNTNGCQFFITT 177 Query: 132 ADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 +LD VFG+++ D + ++ V PY P P+ ++ L Sbjct: 178 KKCEWLDGKN-----VVFGRIIDN-DSLLLLKKIENVSVTPYIYKPKIPINVVECGEL 229 >5YZG-3 nrPDB Length = 754 Score = 44.3 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 33/106 (31%), Positives = 50/106 (47%), Gaps = 9/106 (8%) Query: 65 YNNTTFHRVIPGFMIQGGGFTE---QMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKD 121 Y + FHRV+ FM+QGG F+E + + ++E+ N ++MA KD Sbjct: 60 YKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRG-KD 118 Query: 122 SATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPT 167 + SQFFI LD + VFG+V+ G +V +I T Sbjct: 119 TNGSQFFITTKPTPHLDG-----HHVVFGQVISGQEVVREIENQKT 159 >3RFY-A nrPDB Length = 369 Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 43/145 (29%), Positives = 58/145 (40%), Gaps = 32/145 (22%) Query: 44 LDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGG-------GFTEQMQQKKPNPP 96 LD APV+ NFVD V FY+ R GF++Q G GF + +K P Sbjct: 194 LDGYNAPVTAGNFVDLVERHFYDGMEIQRS-DGFVVQTGDPEGPAEGFIDPSTEKTRTVP 252 Query: 97 IK-------------NEADNGLR--------NTRGTIAMARTA-DKDSATSQFFINVADN 134 ++ + GL N GT+AMAR + DS +SQ F + ++ Sbjct: 253 LEIMVTGEKTPFYGSTLEELGLYKAQVVIPFNAFGTMAMAREEFENDSGSSQVFWLLKES 312 Query: 135 AFLDHGQR--DFGYAVFGKVVKGMD 157 D YAVFG V D Sbjct: 313 ELTPSNSNILDGRYAVFGYVTDNED 337 >5JHE-A nrPDB Length = 397 Score = 34.3 bits (77), Expect = 0.029, Method: Compositional matrix adjust. Identities = 50/203 (24%), Positives = 69/203 (33%), Gaps = 50/203 (24%) Query: 28 DPHVLLTTSA-----GNIELELDKQKAPVSVQNFVDYVNSGF-----------YNNTTFH 71 DP V L S G I +L ++KAP + +NF Y FH Sbjct: 8 DPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFH 67 Query: 72 RVIPGFMIQGGGFT-----------------------EQMQQKKPNPPIKNEADNGLRNT 108 RV+ FMIQ G E+++ + N D L Sbjct: 68 RVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEF 127 Query: 109 RG--TIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVP 166 T+ MA ++ SQFFI L+ G+ +++FG+VV G V I Sbjct: 128 VEPFTLGMANLGSPNTNNSQFFITTYAAPHLN-GK----HSIFGQVVHGKSVVRTIENCR 182 Query: 167 THDVGPYQNVPSKPVVILSAKVL 189 G VP V I V Sbjct: 183 VDSDG----VPESDVRISDCGVW 201 >5GM6-b nrPDB Length = 301 Score = 32.7 bits (73), Expect = 0.088, Method: Compositional matrix adjust. Identities = 13/45 (28%), Positives = 25/45 (55%) Query: 31 VLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIP 75 +L T+ GNI +EL ++ P + + F+ ++ G + N F + P Sbjct: 13 CILYTTKGNIAIELWAKECPETCKRFLSMLSDGTFTNGEFKELKP 57 >2JGP-A nrPDB Length = 520 Score = 30.4 bits (67), Expect = 0.46, Method: Compositional matrix adjust. Identities = 20/81 (24%), Positives = 39/81 (48%), Gaps = 4/81 (4%) Query: 111 TIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHD- 169 T+AM ++ S+F V NA +G +D+ F ++V+ + +A +S+ P D Sbjct: 374 TLAMRNKPQREKTFSEFLQEVKQNALDAYGHQDYP---FEELVEKLAIARDLSRNPLFDT 430 Query: 170 VGPYQNVPSKPVVILSAKVLP 190 V +QN + + + + P Sbjct: 431 VFTFQNSTEEVMTLPECTLAP 451 >4V61-AG nrPDB Length = 155 Score = 29.6 bits (65), Expect = 0.77, Method: Compositional matrix adjust. Identities = 14/46 (30%), Positives = 22/46 (47%), Gaps = 1/46 (2%) Query: 109 RGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGKVVK 154 RGT+ +TA D +N+ N L HG++ Y + + VK Sbjct: 4 RGTVE-EKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQILYRAVK 48 >3AIC-A nrPDB Length = 844 Score = 29.3 bits (64), Expect = 0.98, Method: Compositional matrix adjust. Identities = 22/73 (30%), Positives = 32/73 (43%), Gaps = 16/73 (21%) Query: 81 GGGFTEQMQQKKPNPPIKNEADNGL-------------RNTRGTIAMARTAD---KDSAT 124 GG F E++Q K P + + G+ + GT + R A KD AT Sbjct: 765 GGAFLEELQAKYPELFARKQISTGVPMDPSVKIKQWSAKYFNGTNILGRGAGYVLKDQAT 824 Query: 125 SQFFINVADNAFL 137 + +F V+DN FL Sbjct: 825 NTYFSLVSDNTFL 837 >5VPU-A nrPDB Length = 523 Score = 29.3 bits (64), Expect = 1.1, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 3/61 (4%) Query: 1 MFKSTLAAMAAV-FALSALSPAAMAAKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDY 59 +F + + A+ AV L + A MA KG H+L+T GN+E D + V Q+ + Sbjct: 418 VFDAAVKAVEAVDTCLGRVYEAVMAKKG--HMLITADHGNVEQMQDYESGQVHTQHTTEL 475 Query: 60 V 60 V Sbjct: 476 V 476 >2OSE-A nrPDB Length = 234 Score = 26.2 bits (56), Expect = 8.2, Method: Compositional matrix adjust. Identities = 38/168 (22%), Positives = 65/168 (38%), Gaps = 36/168 (21%) Query: 31 VLLTTSAGNIELELDKQKAPVSVQNFVDYVN--------------------SGFYNNTTF 70 VL G ++++L + P V+NFV N + Y F Sbjct: 22 VLNNEIIGRLQIKLFRDAFPAGVENFVQLTNGKTYRVNSNGTGKYKYNRHINRTYEGCKF 81 Query: 71 HRVIPG-FMIQG------GGFTEQMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSA 123 H V+ +++ G G + +P PP+ + ++G +++ D+ Sbjct: 82 HNVLHNNYIVSGDIYNSNGSSAGTVYCDEPIPPVFGDYFYP-HESKGLLSLVPYTDESGN 140 Query: 124 T---SQFFINVAD---NAFLDHGQRDFGYAVFGKVVKGMDVADKISQV 165 S F I + D + LD RD V G+V G+DV DKI+ + Sbjct: 141 RYYDSTFMITLDDIRPSNVLDELDRD--QVVIGQVYGGLDVLDKINSM 186 >5M29-A nrPDB Length = 290 Score = 26.2 bits (56), Expect = 8.4, Method: Compositional matrix adjust. Identities = 17/52 (32%), Positives = 24/52 (46%) Query: 8 AMAAVFALSALSPAAMAAKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDY 59 A+A AL+ + A AA ++T S N EL PV V ++ DY Sbjct: 5 AIAIAVALAGFATVAQAASMAAPRVITLSPANTELAFAAGITPVGVSSYSDY 56 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1VAI-A nrPDB 226 3e-60 5YZG-2 nrPDB 203 5e-53 2NUL-A nrPDB 199 8e-52 2A2N-A nrPDB 194 2e-50 3JB9-d nrPDB 193 5e-50 5YZG-3 nrPDB 191 2e-49 4JCP-A nrPDB 190 3e-49 4E1Q-A nrPDB 190 4e-49 4HY7-A nrPDB 190 4e-49 3S6M-A nrPDB 189 5e-49 3T1U-A nrPDB 189 5e-49 1IHG-A nrPDB 189 8e-49 3R49-A nrPDB 189 9e-49 2OK3-A nrPDB 189 9e-49 2HAQ-A nrPDB 188 1e-48 5Z56-z nrPDB 187 2e-48 1XWN-A nrPDB 187 2e-48 4JJM-A nrPDB 187 2e-48 2K7N-A nrPDB 187 2e-48 1QNH-A nrPDB 187 2e-48 5MQF-o nrPDB 187 2e-48 3K2C-A nrPDB 187 3e-48 2POY-A nrPDB 187 3e-48 2MC9-A nrPDB 187 3e-48 2C3B-A nrPDB 186 5e-48 6HMZ-X nrPDB 186 5e-48 2HQ6-A nrPDB 186 5e-48 2CMT-A nrPDB 185 1e-47 3UCH-A nrPDB 183 4e-47 1ZKC-A nrPDB 182 6e-47 1E8K-A nrPDB 182 1e-46 2WFI-A nrPDB 180 2e-46 5O9Z-M nrPDB 180 3e-46 1IST-A nrPDB 180 4e-46 3RDD-A nrPDB 180 4e-46 5YB9-A nrPDB 180 4e-46 1C5F-A nrPDB 179 4e-46 3ICH-A nrPDB 179 5e-46 5TA2-A nrPDB 179 5e-46 4R3E-A nrPDB 179 6e-46 2HE9-A nrPDB 179 7e-46 2HQJ-A nrPDB 179 7e-46 4EYV-A nrPDB 178 1e-45 2FU0-A nrPDB 177 2e-45 1XQ7-A nrPDB 176 5e-45 2CFE-A nrPDB 175 1e-44 2B71-A nrPDB 175 1e-44 1Z81-A nrPDB 174 3e-44 2QER-A nrPDB 173 4e-44 3PMP-A nrPDB 171 1e-43 1H0P-A nrPDB 171 1e-43 2RMC-A nrPDB 170 3e-43 2ESL-A nrPDB 167 3e-42 4R3F-A nrPDB 165 9e-42 4I9Y-A nrPDB 159 8e-40 6HIX-BQ nrPDB 153 5e-38 1W74-A nrPDB 149 8e-37 3BO7-A nrPDB 149 8e-37 2MVZ-A nrPDB 145 1e-35 6HIX-BZ nrPDB 143 5e-35 5EX1-A nrPDB 141 2e-34 3BKP-A nrPDB 135 1e-32 5EX2-A nrPDB 126 5e-30 3RFY-A nrPDB 93 8e-20 Sequences not found previously or not previously below threshold: 5JHE-A nrPDB 140 3e-34 2OSE-A nrPDB 61 2e-10 5GM6-b nrPDB 57 6e-09 2SIL-A nrPDB 32 0.23 2W1Z-A nrPDB 28 2.9 3HRI-A nrPDB 28 3.3 4H4F-A nrPDB 28 3.4 5ZWM-J nrPDB 27 5.4 4YHU-A nrPDB 27 5.4 4YHV-A nrPDB 27 6.3 4AQG-A nrPDB 27 6.5 >1VAI-A nrPDB Length = 166 Score = 226 bits (577), Expect = 3e-60, Method: Composition-based stats. Identities = 165/166 (99%), Positives = 165/166 (99%) Query: 25 AKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGF 84 AKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGF Sbjct: 1 AKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGF 60 Query: 85 TEQMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDF 144 TEQMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDF Sbjct: 61 TEQMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDF 120 Query: 145 GYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVLP 190 GYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSA VLP Sbjct: 121 GYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSATVLP 166 >5YZG-2 nrPDB Length = 646 Score = 203 bits (516), Expect = 5e-53, Method: Composition-based stats. Identities = 60/175 (34%), Positives = 92/175 (52%), Gaps = 16/175 (9%) Query: 21 AAMAAKGDPHV----LLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPG 76 AA A+G V ++ TS G+I +L + P +V+NF + +G+YN TFHR+I G Sbjct: 480 AATQAEGPKRVSDSAIIHTSMGDIHTKLFPVECPKTVENFCVHSRNGYYNGHTFHRIIKG 539 Query: 77 FMIQGGGFTEQ--MQQKKPNPPIKNEADNGLRN-TRGTIAMARTADKDSATSQFFINVAD 133 FMIQ G T + ++E + LR+ T++MA A ++ SQFFI V Sbjct: 540 FMIQTGDPTGTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMAN-AGSNTNGSQFFITVVP 598 Query: 134 NAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKV 188 +LD+ + VFG+V KGM+V +IS V + P + P + V I++ V Sbjct: 599 TPWLDN-----KHTVFGRVTKGMEVVQRISNVKVN---PKTDKPYEDVSIINITV 645 >2NUL-A nrPDB Length = 164 Score = 199 bits (505), Expect = 8e-52, Method: Composition-based stats. Identities = 90/161 (55%), Positives = 110/161 (68%), Gaps = 3/161 (1%) Query: 31 VLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQMQQ 90 V T+ G+I ++ KAP +V+NF+DY GFYNNT FHRVI GFMIQGGGF M+Q Sbjct: 2 VTFHTNHGDIVIKTFDDKAPETVKNFLDYCREGFYNNTIFHRVINGFMIQGGGFEPGMKQ 61 Query: 91 KKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLD---HGQRDFGYA 147 K PIKNEA+NGL+NTRGT+AMART SAT+QFFINV DN FL+ + +GY Sbjct: 62 KATKEPIKNEANNGLKNTRGTLAMARTQAPHSATAQFFINVVDNDFLNFSGESLQGWGYC 121 Query: 148 VFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKV 188 VF +VV GMDV DKI V T G +Q+VP + V+I S V Sbjct: 122 VFAEVVDGMDVVDKIKGVATGRSGMHQDVPKEDVIIESVTV 162 >2A2N-A nrPDB Length = 176 Score = 194 bits (494), Expect = 2e-50, Method: Composition-based stats. Identities = 60/175 (34%), Positives = 92/175 (52%), Gaps = 16/175 (9%) Query: 21 AAMAAKGDPHV----LLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPG 76 AA A+G V ++ TS G+I +L + P +V+NF + +G+YN TFHR+I G Sbjct: 10 AATQAEGPKRVSDSAIIHTSMGDIHTKLFPVECPKTVENFCVHSRNGYYNGHTFHRIIKG 69 Query: 77 FMIQGGGFTEQ--MQQKKPNPPIKNEADNGLRN-TRGTIAMARTADKDSATSQFFINVAD 133 FMIQ G T + ++E + LR+ T++MA A ++ SQFFI V Sbjct: 70 FMIQTGDPTGTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMAN-AGSNTNGSQFFITVVP 128 Query: 134 NAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKV 188 +LD+ + VFG+V KGM+V +IS V + P + P + V I++ V Sbjct: 129 TPWLDN-----KHTVFGRVTKGMEVVQRISNVKVN---PKTDKPYEDVSIINITV 175 >3JB9-d nrPDB Length = 155 Score = 193 bits (490), Expect = 5e-50, Method: Composition-based stats. Identities = 54/163 (33%), Positives = 82/163 (50%), Gaps = 13/163 (7%) Query: 30 HVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQ-- 87 +V L TS G I +EL + AP + QNF G+Y+ FHRVIP F+IQGG T Sbjct: 3 NVELQTSLGKILIELYTEHAPKTCQNFYTLAKEGYYDGVIFHRVIPDFVIQGGDPTGTGR 62 Query: 88 MQQKKPNPPIKNEADNGLRNTR-GTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGY 146 +E + L +T G ++MA A ++ +SQFFI +A +LD + Sbjct: 63 GGTSIYGDKFDDEIHSDLHHTGAGILSMAN-AGPNTNSSQFFITLAPTPWLD-----GKH 116 Query: 147 AVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 +FG+VV G+ V ++ + T + P +P+ I+ A L Sbjct: 117 TIFGRVVSGLSVCKRMGLIRTDS----SDRPIEPLKIIKAVAL 155 >5YZG-3 nrPDB Length = 754 Score = 191 bits (485), Expect = 2e-49, Method: Composition-based stats. Identities = 46/167 (27%), Positives = 65/167 (38%), Gaps = 24/167 (14%) Query: 37 AGNIELELDKQKAPVSVQNFVDYVNSG-----------FYNNTTFHRVIPGFMIQGGGFT 85 AG + EL P + +NF Y + FHRV+ FM+QGG F+ Sbjct: 21 AGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFS 80 Query: 86 EQ---MQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQR 142 E + ++E+ N ++MA KD+ SQFFI LD Sbjct: 81 EGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANR-GKDTNGSQFFITTKPTPHLD---- 135 Query: 143 DFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 + VFG+V+ G +V +I T P V ILS L Sbjct: 136 -GHHVVFGQVISGQEVVREIENQKTDAAS----KPFAEVRILSCGEL 177 >4JCP-A nrPDB Length = 175 Score = 190 bits (483), Expect = 3e-49, Method: Composition-based stats. Identities = 52/188 (27%), Positives = 73/188 (38%), Gaps = 32/188 (17%) Query: 20 PAAMAAKGDPHVLLT-----TSAGNIELELDKQKAPVSVQNFVDYVNSG----------F 64 P +M P V ++AG I +EL P + +NF Sbjct: 2 PGSM---SRPKVFFDITIGGSNAGRIVMELFADIVPKTAENFRCLCTGERGMGRSGKKLH 58 Query: 65 YNNTTFHRVIPGFMIQGGGFTEQMQQKKPNPP---IKNEADNGLRNTRGTIAMARTADKD 121 Y + FHRVIP FM+QGG FT + +E G ++MA A + Sbjct: 59 YKGSKFHRVIPNFMLQGGDFTRGNGTGGESIYGEKFPDENFQEKHTGPGVLSMAN-AGPN 117 Query: 122 SATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPV 181 + SQFFI A +LD + VFG+VV+GM+V + G S + Sbjct: 118 TNGSQFFICTAKTEWLD-----GKHVVFGRVVEGMNVVKAVE-----SKGSQSGRTSADI 167 Query: 182 VILSAKVL 189 VI L Sbjct: 168 VISDCGQL 175 >4E1Q-A nrPDB Length = 207 Score = 190 bits (482), Expect = 4e-49, Method: Composition-based stats. Identities = 57/187 (30%), Positives = 75/187 (40%), Gaps = 29/187 (15%) Query: 21 AAMAAKGDPHVLLTTS-----AGNIELELDKQKAPVSVQNFVDYVNSG----------FY 65 +P V + AG I +EL K P +V+NF Y Sbjct: 32 RGSEFMANPRVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHY 91 Query: 66 NNTTFHRVIPGFMIQGGGFTEQMQQKKPNPPIKNEADNGLRN---TRGTIAMARTADKDS 122 + FHRVIP FM QGG FT + + AD + G ++MA A ++ Sbjct: 92 KGSAFHRVIPDFMCQGGDFTRGNGTGGESIYGEKFADEKFVHKHTKPGILSMAN-AGPNT 150 Query: 123 ATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVV 182 SQFFI +LD + VFG+VV+GMDV I +V G SK VV Sbjct: 151 NGSQFFICTVPCNWLD-----GKHVVFGEVVEGMDVVKNIEKV-----GSRSGTCSKQVV 200 Query: 183 ILSAKVL 189 I L Sbjct: 201 IADCGQL 207 >4HY7-A nrPDB Length = 171 Score = 190 bits (482), Expect = 4e-49, Method: Composition-based stats. Identities = 57/181 (31%), Positives = 75/181 (41%), Gaps = 29/181 (16%) Query: 27 GDPHVLLTTS-----AGNIELELDKQKAPVSVQNFVDYVNSG----------FYNNTTFH 71 +P V + AG I +EL K P +V+NF Y + FH Sbjct: 2 ANPRVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSAFH 61 Query: 72 RVIPGFMIQGGGFTEQMQQKKPNPPIKNEADNGLRN---TRGTIAMARTADKDSATSQFF 128 RVIP FM QGG FT + + AD + G ++MA A ++ SQFF Sbjct: 62 RVIPDFMCQGGDFTRGNGTGGESIYGEKFADEKFVHKHTKPGILSMAN-AGPNTNGSQFF 120 Query: 129 INVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKV 188 I +LD + VFG+VV+GMDV I +V G SK VVI Sbjct: 121 ICTVPCNWLD-----GKHVVFGEVVEGMDVVKNIEKV-----GSRSGTCSKQVVIADCGQ 170 Query: 189 L 189 L Sbjct: 171 L 171 >3S6M-A nrPDB Length = 167 Score = 189 bits (481), Expect = 5e-49, Method: Composition-based stats. Identities = 92/162 (56%), Positives = 115/162 (70%), Gaps = 3/162 (1%) Query: 31 VLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQMQQ 90 V L T+ G I+LELD+ KAP +V+NF++YV G Y+ T FHRVI GFMIQGGGF ++Q Sbjct: 6 VELHTNHGVIKLELDEAKAPKTVENFLNYVKKGHYDGTIFHRVINGFMIQGGGFEPGLKQ 65 Query: 91 KKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQ---RDFGYA 147 K + PI NEA+NGL+N TIAMART D SAT+QFFINV DN FL+H + +GYA Sbjct: 66 KPTDAPIANEANNGLKNDTYTIAMARTNDPHSATAQFFINVNDNEFLNHSSPTPQGWGYA 125 Query: 148 VFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 VFGKVV+G D+ DKI V T G +Q+VP+ VVI A V+ Sbjct: 126 VFGKVVEGQDIVDKIKAVKTGSKGFHQDVPNDDVVIEKAVVV 167 >3T1U-A nrPDB Length = 163 Score = 189 bits (481), Expect = 5e-49, Method: Composition-based stats. Identities = 86/162 (53%), Positives = 106/162 (65%), Gaps = 3/162 (1%) Query: 31 VLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQMQQ 90 + L T+ G I L+L KAP + NF YV G Y+ T FHRVI GFMIQGGGF M+Q Sbjct: 2 IKLQTNHGTITLKLFADKAPETAANFEQYVKDGHYDGTIFHRVIDGFMIQGGGFEPGMKQ 61 Query: 91 KKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDH---GQRDFGYA 147 K PIKNEA+NGL N + TIAMART D SA++QFFINV DNAFLDH +GYA Sbjct: 62 KSTRAPIKNEANNGLSNKKYTIAMARTPDPHSASAQFFINVKDNAFLDHTAPTAHGWGYA 121 Query: 148 VFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 VFG+VV+G DV D+I V T + +VP V+I A+++ Sbjct: 122 VFGEVVEGTDVVDRIKSVATGSRAGHGDVPVDDVIIEKAEIV 163 >1IHG-A nrPDB Length = 370 Score = 189 bits (479), Expect = 8e-49, Method: Composition-based stats. Identities = 49/183 (26%), Positives = 69/183 (37%), Gaps = 30/183 (16%) Query: 26 KGDPHVLLTTS-----AGNIELELDKQKAPVSVQNFVDYVNSG-----------FYNNTT 69 +P V G I LEL P + +NF + Sbjct: 13 PSNPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCTGEKGIGPTTGKPLHFKGCP 72 Query: 70 FHRVIPGFMIQGGGFTEQMQQKKPNPP---IKNEADNGLRNTRGTIAMARTADKDSATSQ 126 FHR+I FMIQGG F+ Q + ++E + + G ++MA A ++ SQ Sbjct: 73 FHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDKEGLLSMAN-AGSNTNGSQ 131 Query: 127 FFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSA 186 FFI LD + VFG+V+KGM VA + V P+K VI Sbjct: 132 FFITTVPTPHLD-----GKHVVFGQVIKGMGVAKILENVEV-----KGEKPAKLCVIAEC 181 Query: 187 KVL 189 L Sbjct: 182 GEL 184 >3R49-A nrPDB Length = 166 Score = 189 bits (479), Expect = 9e-49, Method: Composition-based stats. Identities = 54/174 (31%), Positives = 70/174 (40%), Gaps = 22/174 (12%) Query: 27 GDPHVLLTTSA-----GNIELELDKQKAPVSVQNFVDYVNSG---FYNNTTFHRVIPGFM 78 G+P V L A G + LEL P + +NF Y +TFHRVIP FM Sbjct: 3 GNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPSFM 62 Query: 79 IQGGGFTEQMQQKKPNPP---IKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNA 135 Q G FT + +E G ++MA A ++ SQFFI Sbjct: 63 CQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMAN-AGPNTNGSQFFICTIKTD 121 Query: 136 FLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 +LD + VFG V++GMDV KI G SK +VI L Sbjct: 122 WLD-----GKHVVFGHVIEGMDVVKKIE-----SFGSKSGRTSKKIVITDCGQL 165 >2OK3-A nrPDB Length = 161 Score = 189 bits (479), Expect = 9e-49, Method: Composition-based stats. Identities = 47/161 (29%), Positives = 77/161 (47%), Gaps = 12/161 (7%) Query: 31 VLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQMQQ 90 V L T G+I++E+ ++ P + +NF+ S +YN FHR I GFM+Q G T + Sbjct: 3 VTLHTDVGDIKIEVFCERTPKTCENFLALCASNYYNGCIFHRNIKGFMVQTGDPTGTGRG 62 Query: 91 K--KPNPPIKNEADNGLRN-TRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYA 147 ++E L++ RG ++MA ++ SQFFI LD Y Sbjct: 63 GNSIWGKKFEDEYSEYLKHNVRGVVSMANN-GPNTNGSQFFITYGKQPHLD-----MKYT 116 Query: 148 VFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKV 188 VFGKV+ G++ D++ ++P ++ P V I + Sbjct: 117 VFGKVIDGLETLDELEKLPVNE---KTYRPLNDVHIKDITI 154 >2HAQ-A nrPDB Length = 172 Score = 188 bits (477), Expect = 1e-48, Method: Composition-based stats. Identities = 55/176 (31%), Positives = 83/176 (47%), Gaps = 15/176 (8%) Query: 19 SPAAMAAKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGF---YNNTTFHRVIP 75 P A ++ + G I + L + AP++ +NF Y ++ FHRVI Sbjct: 7 EPEVTAKVYFDVMIDSEPLGRITIGLFGKDAPLTTENFRQLCTGEHGFGYKDSIFHRVIQ 66 Query: 76 GFMIQGGGFTEQMQQKKPNPPIKNEADNGL--RNTRGTIAMARTADKDSATSQFFINVAD 133 FMIQGG FT + + AD L ++ G ++MA A ++ SQFFI A Sbjct: 67 NFMIQGGDFTNFDGTGGKSIYGEKFADENLNVKHFVGALSMAN-AGPNTNGSQFFITTAP 125 Query: 134 NAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 +LD + VFGKV+ GMDV +I + T+ + P KPV I+++ L Sbjct: 126 TPWLD-----GRHVVFGKVLDGMDVVLRIEKTKTNS----HDRPVKPVKIVASGEL 172 >5Z56-z nrPDB Length = 472 Score = 187 bits (476), Expect = 2e-48, Method: Composition-based stats. Identities = 59/171 (34%), Positives = 88/171 (51%), Gaps = 16/171 (9%) Query: 24 AAKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGG 83 + VLL T+AG+I++EL ++AP + +NF+ +Y+NT FHRV+PGF++QGG Sbjct: 8 EPPTNGKVLLKTTAGDIDIELWSKEAPKACRNFIQLCLEAYYDNTIFHRVVPGFIVQGGD 67 Query: 84 FTEQ--MQQKKPNPPIKNEADNGLR-NTRGTIAMARTADKDSATSQFFINVADNAFLDHG 140 T + P K+E + LR N RG +AMA D SQFF + L++ Sbjct: 68 PTGTGSGGESIYGAPFKDEFHSRLRFNRRGLVAMANAGSHD-NGSQFFFTLGRADELNN- 125 Query: 141 QRDFGYAVFGKVVKGMDVAD--KISQVPTHDVGPYQNVPSKPVVILSAKVL 189 + +FGKV G V + ++S+V D P P I S +VL Sbjct: 126 ----KHTIFGKVT-GDTVYNMLRLSEVDIDD----DERPHNPHKIKSCEVL 167 >1XWN-A nrPDB Length = 174 Score = 187 bits (476), Expect = 2e-48, Method: Composition-based stats. Identities = 56/162 (34%), Positives = 84/162 (51%), Gaps = 13/162 (8%) Query: 28 DPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQ 87 P+V L TS G I LEL + AP + +NF + G+YN T FHR+I FMIQGG T Sbjct: 11 PPNVYLETSMGIIVLELYWKHAPKTCKNFAELARRGYYNGTKFHRIIKDFMIQGGDPTGT 70 Query: 88 MQQK--KPNPPIKNEADNGLRNTR-GTIAMARTADKDSATSQFFINVADNAFLDHGQRDF 144 + ++E L+ T G +AMA A D+ SQFF+ +A +LD Sbjct: 71 GRGGASIYGKQFEDELHPDLKFTGAGILAMAN-AGPDTNGSQFFVTLAPTQWLD-----G 124 Query: 145 GYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSA 186 + +FG+V +G+ + +++ V T+ Q+ P V I+ A Sbjct: 125 KHTIFGRVCQGIGMVNRVGMVETNS----QDRPVDDVKIIKA 162 >4JJM-A nrPDB Length = 175 Score = 187 bits (476), Expect = 2e-48, Method: Composition-based stats. Identities = 55/180 (30%), Positives = 74/180 (41%), Gaps = 29/180 (16%) Query: 28 DPHVLLTTS-----AGNIELELDKQKAPVSVQNFVDYVNSG----------FYNNTTFHR 72 +P V + AG I +EL P + +NF Y ++FHR Sbjct: 6 NPKVFFDMTVGGQPAGRIVMELFADVTPRTAENFRALCTGEKGIGKSGKPLHYKGSSFHR 65 Query: 73 VIPGFMIQGGGFTEQMQQKKPNPP---IKNEADNGLRNTRGTIAMARTADKDSATSQFFI 129 VIPGFM QGG FT + +E G ++MA A + SQFF+ Sbjct: 66 VIPGFMCQGGDFTAGNGTGGESIYGSKFADENFVKKHTGPGILSMAN-AGPGTNGSQFFV 124 Query: 130 NVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 A +LD + VFG+VV+GMDV I +V G +KPVVI L Sbjct: 125 CTAKTEWLD-----GKHVVFGQVVEGMDVVKAIEKV-----GSSSGRTNKPVVIADCGQL 174 >2K7N-A nrPDB Length = 203 Score = 187 bits (476), Expect = 2e-48, Method: Composition-based stats. Identities = 56/162 (34%), Positives = 84/162 (51%), Gaps = 13/162 (8%) Query: 28 DPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQ 87 P+V L TS G I LEL + AP + +NF + G+YN T FHR+I FMIQGG T Sbjct: 11 PPNVYLETSMGIIVLELYWKHAPKTCKNFAELARRGYYNGTKFHRIIKDFMIQGGDPTGT 70 Query: 88 MQQK--KPNPPIKNEADNGLRNTR-GTIAMARTADKDSATSQFFINVADNAFLDHGQRDF 144 + ++E L+ T G +AMA A D+ SQFF+ +A +LD Sbjct: 71 GRGGASIYGKQFEDELHPDLKFTGAGILAMAN-AGPDTNGSQFFVTLAPTQWLD-----G 124 Query: 145 GYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSA 186 + +FG+V +G+ + +++ V T+ Q+ P V I+ A Sbjct: 125 KHTIFGRVCQGIGMVNRVGMVETNS----QDRPVDDVKIIKA 162 >1QNH-A nrPDB Length = 170 Score = 187 bits (475), Expect = 2e-48, Method: Composition-based stats. Identities = 45/166 (27%), Positives = 69/166 (41%), Gaps = 23/166 (13%) Query: 35 TSAGNIELELDKQKAPVSVQNFVDYVNSG---------FYNNTTFHRVIPGFMIQGGGFT 85 ++AG I EL P + +NF Y N+ FHR+IP FM QGG T Sbjct: 15 SNAGRIIFELFSDITPRTCENFRALCTGEKIGSRGKNLHYKNSIFHRIIPQFMCQGGDIT 74 Query: 86 EQMQQKKPNPP---IKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQR 142 + +E N + G ++MA A ++ +SQF I + +LD Sbjct: 75 NGNGSGGESIYGRSFTDENFNMKHDQPGLLSMAN-AGPNTNSSQFLITLVPCPWLD---- 129 Query: 143 DFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKV 188 + VFGKV++GM+V ++ + G + VVI Sbjct: 130 -GKHVVFGKVIEGMNVVREMEK-----EGAKSGYVKRSVVITDCGE 169 >5MQF-o nrPDB Length = 301 Score = 187 bits (475), Expect = 2e-48, Method: Composition-based stats. Identities = 48/181 (26%), Positives = 76/181 (41%), Gaps = 22/181 (12%) Query: 19 SPAAMAAKGDPHVLLTTS-----AGNIELELDKQKAPVSVQNFVDYVN--SGF-YNNTTF 70 P A A+ +P V + AG I++ L P++ +NF GF + ++F Sbjct: 130 EPIAKKARSNPQVYMDIKIGNKPAGRIQMLLRSDVVPMTAENFRCLCTHEKGFGFKGSSF 189 Query: 71 HRVIPGFMIQGGGFTEQMQQKKPNPP---IKNEADNGLRNTRGTIAMARTADKDSATSQF 127 HR+IP FM QGG FT + +E G ++MA + ++ SQF Sbjct: 190 HRIIPQFMCQGGDFTNHNGTGGKSIYGKKFDDENFILKHTGPGLLSMANS-GPNTNGSQF 248 Query: 128 FINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAK 187 F+ +LD + VFG+V +G+DV +I G P + V+I Sbjct: 249 FLTCDKTDWLD-----GKHVVFGEVTEGLDVLRQIEAQ-----GSKDGKPKQKVIIADCG 298 Query: 188 V 188 Sbjct: 299 E 299 >3K2C-A nrPDB Length = 193 Score = 187 bits (474), Expect = 3e-48, Method: Composition-based stats. Identities = 50/181 (27%), Positives = 77/181 (42%), Gaps = 20/181 (11%) Query: 20 PAAMAAKGDPHVLLT-----TSAGNIELELDKQKAPVSVQNFVDYV---NSGFYNNTTFH 71 P +MA + +V S G I ++L+ P + +NF Y +TFH Sbjct: 19 PGSMAKEASGNVYFDVYANEESLGRIVMKLEDDIVPKTAKNFRTLCERPKGEGYKGSTFH 78 Query: 72 RVIPGFMIQGGGFTEQMQQKKPNPP---IKNEADNGLRNTRGTIAMARTADKDSATSQFF 128 R+IPGFM+QGG +T + +E G ++MA + SQFF Sbjct: 79 RIIPGFMVQGGDYTAHNGTGGRSIYGEKFPDENFELKHTKEGILSMANCGA-HTNGSQFF 137 Query: 129 INVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKV 188 I + +LD + VFG+VV+GMDV KI++ + + + I V Sbjct: 138 ITLGKTQWLDE-----KHVVFGEVVEGMDVVHKIAKYGSESGQVKKG---YRIEIRDCGV 189 Query: 189 L 189 L Sbjct: 190 L 190 >2POY-A nrPDB Length = 186 Score = 187 bits (474), Expect = 3e-48, Method: Composition-based stats. Identities = 53/181 (29%), Positives = 78/181 (43%), Gaps = 29/181 (16%) Query: 26 KGDPHVLLT-----TSAGNIELELDKQKAPVSVQNFVDYVNSG----------FYNNTTF 70 +G+P V T AG I +EL K P++ +NF Y + F Sbjct: 17 QGNPVVYFDISIGQTPAGRITMELFADKVPITAENFRALCTGEKGMGQSGKPLCYTGSFF 76 Query: 71 HRVIPGFMIQGGGFTEQMQQKKPNPP---IKNEADNGLRNTRGTIAMARTADKDSATSQF 127 HR+IP FMIQGG FT + ++E + ++MA A ++ SQF Sbjct: 77 HRIIPQFMIQGGDFTRGDGTGGESIYGSKFRDENFVYTHDAPFLLSMAN-AGPNTNGSQF 135 Query: 128 FINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAK 187 FI +LD + VFGKV++GM+V I + G P+K V I ++ Sbjct: 136 FITTVPCPWLD-----GKHVVFGKVLEGMEVVKSIEKC-----GSQNGKPTKSVCITASG 185 Query: 188 V 188 V Sbjct: 186 V 186 >2MC9-A nrPDB Length = 178 Score = 187 bits (474), Expect = 3e-48, Method: Composition-based stats. Identities = 55/180 (30%), Positives = 75/180 (41%), Gaps = 29/180 (16%) Query: 28 DPHVLLTTS-----AGNIELELDKQKAPVSVQNFVDYVNSG----------FYNNTTFHR 72 +P V S AG I +EL P + +NF Y +++FHR Sbjct: 9 NPRVFFDMSVGGQPAGRIVMELFADTTPRTAENFRALCTGEKGTGRSGKPLHYKDSSFHR 68 Query: 73 VIPGFMIQGGGFTEQMQQKKPNPP---IKNEADNGLRNTRGTIAMARTADKDSATSQFFI 129 VIPGFM QGG FT + +E G ++MA A ++ SQFFI Sbjct: 69 VIPGFMCQGGDFTAGNGTGGESIYGAKFADENFIKKHTGPGILSMAN-AGPNTNGSQFFI 127 Query: 130 NVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 A +LD + VFG+VV+GMDV I +V G +K VV+ L Sbjct: 128 CTAKTEWLD-----GKHVVFGQVVEGMDVVKAIEKV-----GSSSGRTAKKVVVEDCGQL 177 >2C3B-A nrPDB Length = 172 Score = 186 bits (472), Expect = 5e-48, Method: Composition-based stats. Identities = 50/191 (26%), Positives = 77/191 (40%), Gaps = 28/191 (14%) Query: 8 AMAAVFALSALSPAAMAAKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVN---SGF 64 +M+ VF +P A T G I L + P + +NF + Sbjct: 1 SMSQVFFDVEYAPVGTA---------ETKVGRIVFNLFDKDVPKTAKNFRELCKRPAGEG 51 Query: 65 YNNTTFHRVIPGFMIQGGGFTEQMQQKKPNPP---IKNEADNGLRNTRGTIAMARTADKD 121 Y +TFHR+IP FMIQGG FT + +E + + +G ++MA A + Sbjct: 52 YRESTFHRIIPNFMIQGGDFTRGNGTGGRSIYGDKFADENFSRKHDKKGILSMAN-AGPN 110 Query: 122 SATSQFFINVADNAFLDHGQRDFGYAVFGKVVK--GMDVADKISQVPTHDVGPYQN-VPS 178 + SQFFI A ++LD + VFG+V V +I + + N P Sbjct: 111 TNGSQFFITTAVTSWLD-----GKHVVFGEVADEKSYSVVKEIEALGSSSGSVRSNTRP- 164 Query: 179 KPVVILSAKVL 189 I++ L Sbjct: 165 ---KIVNCGEL 172 >6HMZ-X nrPDB Length = 180 Score = 186 bits (472), Expect = 5e-48, Method: Composition-based stats. Identities = 51/181 (28%), Positives = 73/181 (40%), Gaps = 29/181 (16%) Query: 27 GDPHVLLTT-----SAGNIELELDKQKAPVSVQNFVDYVNSG----------FYNNTTFH 71 +P V AG + +EL P + NF Y + FH Sbjct: 2 ANPKVFFDILIGKMKAGRVVMELFADVTPRTADNFRALCTGEKGIGQAGKALHYKGSAFH 61 Query: 72 RVIPGFMIQGGGFTEQMQQKKPNPP---IKNEADNGLRNTRGTIAMARTADKDSATSQFF 128 R+IPGFM QGG FT + ++E G ++MA + ++ SQFF Sbjct: 62 RIIPGFMCQGGDFTRGNGTGGESIYGAKFQDENFKLKHTGPGILSMANS-GPNTNGSQFF 120 Query: 129 INVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKV 188 I A+LD + VFGKVV G +V + +V G + V S+PVVI Sbjct: 121 ICTDKTAWLD-----GKHVVFGKVVDGYNVVKAMEKV-----GSERGVTSEPVVIEDCGE 170 Query: 189 L 189 + Sbjct: 171 I 171 >2HQ6-A nrPDB Length = 185 Score = 186 bits (472), Expect = 5e-48, Method: Composition-based stats. Identities = 61/178 (34%), Positives = 90/178 (50%), Gaps = 16/178 (8%) Query: 17 ALSPAAMAAKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPG 76 L P + VLL T+AG+I++EL ++AP + +NF+ +Y+NT FHRV+PG Sbjct: 13 GLVPRGSEPPTNGKVLLKTTAGDIDIELWSKEAPKACRNFIQLCLEAYYDNTIFHRVVPG 72 Query: 77 FMIQGGGFTEQ--MQQKKPNPPIKNEADNGLR-NTRGTIAMARTADKDSATSQFFINVAD 133 F++QGG T + P K+E + LR N RG +AMA D SQFF + Sbjct: 73 FIVQGGDPTGTGSGGESIYGAPFKDEFHSRLRFNRRGLVAMANAGSHD-NGSQFFFTLGR 131 Query: 134 NAFLDHGQRDFGYAVFGKVVKGMDVAD--KISQVPTHDVGPYQNVPSKPVVILSAKVL 189 L++ + +FGKV G V + ++S+V D P P I S +VL Sbjct: 132 ADELNN-----KHTIFGKVT-GDTVYNMLRLSEVDIDD----DERPHNPHKIKSCEVL 179 >2CMT-A nrPDB Length = 172 Score = 185 bits (469), Expect = 1e-47, Method: Composition-based stats. Identities = 49/178 (27%), Positives = 69/178 (38%), Gaps = 22/178 (12%) Query: 23 MAAKGDPHVLLTT-----SAGNIELELDKQKAPVSVQNFVDYVNSG---FYNNTTFHRVI 74 + P V AG I +EL P + +NF Y+N FHRVI Sbjct: 5 KQKRNLPRVFFDIRIGNGDAGRIVMELRSDIVPRTAENFRALCTGERGFGYHNCCFHRVI 64 Query: 75 PGFMIQGGGFTEQMQQKKPNPP---IKNEADNGLRNTRGTIAMARTADKDSATSQFFINV 131 P FM QGG F + + +E G ++MA + ++ SQFFI Sbjct: 65 PQFMCQGGDFVKGDGTGGKSIYGRKFDDENFQLRHEGFGVLSMANS-GPNTNGSQFFICT 123 Query: 132 ADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 +LD + VFG+VV G +V K+ V G +PV+I L Sbjct: 124 TKCDWLD-----GKHVVFGRVVDGQNVVKKMESV-----GSKSGKVKEPVIISRCGEL 171 >3UCH-A nrPDB Length = 174 Score = 183 bits (464), Expect = 4e-47, Method: Composition-based stats. Identities = 48/181 (26%), Positives = 76/181 (41%), Gaps = 22/181 (12%) Query: 19 SPAAMAAKGDPHVLLTTS-----AGNIELELDKQKAPVSVQNFVDYVN--SGF-YNNTTF 70 P A A+ +P V + AG I++ L P++ +NF GF + ++F Sbjct: 3 EPIAKKARSNPQVYMDIKIGNKPAGRIQMLLRSDVVPMTAENFRCLCTHEKGFGFKGSSF 62 Query: 71 HRVIPGFMIQGGGFTEQMQQKKPNPP---IKNEADNGLRNTRGTIAMARTADKDSATSQF 127 HR+IP FM QGG FT + +E G ++MA + ++ SQF Sbjct: 63 HRIIPQFMCQGGDFTNHNGTGGKSIYGKKFDDENFILKHTGPGLLSMANS-GPNTNGSQF 121 Query: 128 FINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAK 187 F+ +LD + VFG+V +G+DV +I G P + V+I Sbjct: 122 FLTCDKTDWLD-----GKHVVFGEVTEGLDVLRQIEAQ-----GSKDGKPKQKVIIADCG 171 Query: 188 V 188 Sbjct: 172 E 172 >1ZKC-A nrPDB Length = 197 Score = 182 bits (463), Expect = 6e-47, Method: Composition-based stats. Identities = 51/171 (29%), Positives = 80/171 (46%), Gaps = 12/171 (7%) Query: 22 AMAAKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQ- 80 + +G +V L T+ G++ LEL P + +NF+ +Y+ T FHR I F+IQ Sbjct: 13 GLVPRGSGYVRLHTNKGDLNLELHCDLTPKTCENFIRLCKKHYYDGTIFHRSIRNFVIQG 72 Query: 81 -GGGFTEQMQQKKPNPPIKNEADNGLRNT-RGTIAMARTADKDSATSQFFINVADNAFLD 138 T + P K+E L +T RG ++MA + +S SQFFI A+LD Sbjct: 73 GDPTGTGTGGESYWGKPFKDEFRPNLSHTGRGILSMANS-GPNSNRSQFFITFRSCAYLD 131 Query: 139 HGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 + +FG+VV G DV + V + P + P + + I + V Sbjct: 132 K-----KHTIFGRVVGGFDVLTAMENVESD---PKTDRPKEEIRIDATTVF 174 >1E8K-A nrPDB Length = 173 Score = 182 bits (461), Expect = 1e-46, Method: Composition-based stats. Identities = 44/168 (26%), Positives = 65/168 (38%), Gaps = 24/168 (14%) Query: 35 TSAGNIELELDKQKAPVSVQNFVDYVNSG----------FYNNTTFHRVIPGFMIQGGGF 84 ++G I +EL P + NF + + FHR+IP FMIQGG F Sbjct: 15 KASGRIVMELYDDVVPKTAGNFRALCTGENGIGKSGKPLHFKGSKFHRIIPNFMIQGGDF 74 Query: 85 TEQMQQKKPNPP---IKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQ 141 T + +E G ++MA A ++ SQFF+ +LD Sbjct: 75 TRGNGTGGESIYGEKFPDENFKEKHTGPGVLSMAN-AGPNTNGSQFFLCTVKTEWLD--- 130 Query: 142 RDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 + VFG+VV+G+DV + G P K +I L Sbjct: 131 --GKHVVFGRVVEGLDVVKAVE-----SNGSQSGKPVKDCMIADCGQL 171 >2WFI-A nrPDB Length = 179 Score = 180 bits (458), Expect = 2e-46, Method: Composition-based stats. Identities = 46/167 (27%), Positives = 65/167 (38%), Gaps = 24/167 (14%) Query: 37 AGNIELELDKQKAPVSVQNFVDYVNSG-----------FYNNTTFHRVIPGFMIQGGGFT 85 AG + EL P + +NF Y + FHRV+ FM+QGG F+ Sbjct: 23 AGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFS 82 Query: 86 EQ---MQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQR 142 E + ++E+ N ++MA KD+ SQFFI LD Sbjct: 83 EGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANR-GKDTNGSQFFITTKPTPHLD---- 137 Query: 143 DFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 + VFG+V+ G +V +I T P V ILS L Sbjct: 138 -GHHVVFGQVISGQEVVREIENQKTDAAS----KPFAEVRILSCGEL 179 >5O9Z-M nrPDB Length = 177 Score = 180 bits (456), Expect = 3e-46, Method: Composition-based stats. Identities = 53/185 (28%), Positives = 77/185 (41%), Gaps = 26/185 (14%) Query: 21 AAMAAKGDPHVLLTTS-----AGNIELELDKQKAPVSVQNFVDYVNSGF--------YNN 67 A ++ +P V S G +++EL P + +NF + F Y Sbjct: 3 VANSSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFRKDGVPIGYKG 62 Query: 68 TTFHRVIPGFMIQGGGFTEQMQQKKPNP---PIKNEADNGLRNTRGTIAMARTADKDSAT 124 +TFHRVI FMIQGG F + P +E + G ++MA + + Sbjct: 63 STFHRVIKDFMIQGGDFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMANS-GPSTNG 121 Query: 125 SQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVIL 184 QFFI + +LD + VFGK++ G+ V KI VPT N P PVVI Sbjct: 122 CQFFITCSKCDWLD-----GKHVVFGKIIDGLLVMRKIENVPTGP----NNKPKLPVVIS 172 Query: 185 SAKVL 189 + Sbjct: 173 QCGEM 177 >1IST-A nrPDB Length = 162 Score = 180 bits (456), Expect = 4e-46, Method: Composition-based stats. Identities = 47/187 (25%), Positives = 71/187 (37%), Gaps = 31/187 (16%) Query: 9 MAAVFALSALSPAAMAAKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSG---FY 65 M+ V+ A G P G + +L P + +NF Y Sbjct: 1 MSQVYFDVE-------ADGQP-------IGRVVFKLYNDIVPKTAENFRALCTGEKGFGY 46 Query: 66 NNTTFHRVIPGFMIQGGGFTEQMQQKKPNPP---IKNEADNGLRNTRGTIAMARTADKDS 122 + FHRVIP FM+QGG FT + +E + G ++MA A ++ Sbjct: 47 AGSPFHRVIPDFMLQGGDFTAGNGTGGKSIYGGKFPDENFKKHHDRPGLLSMAN-AGPNT 105 Query: 123 ATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVV 182 SQFFI +LD + VFG+VV G D+ K+ + G +V Sbjct: 106 NGSQFFITTVPCPWLD-----GKHVVFGEVVDGYDIVKKVESL-----GSPSGATKARIV 155 Query: 183 ILSAKVL 189 + + L Sbjct: 156 VAKSGEL 162 >3RDD-A nrPDB Length = 184 Score = 180 bits (456), Expect = 4e-46, Method: Composition-based stats. Identities = 48/173 (27%), Positives = 71/173 (41%), Gaps = 22/173 (12%) Query: 28 DPHVLLTTS-----AGNIELELDKQKAPVSVQNFVDYVNSG---FYNNTTFHRVIPGFMI 79 +P V + G + EL K P + +NF Y + FHR+IPGFM Sbjct: 22 NPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMC 81 Query: 80 QGGGFTEQMQQKKPNPP---IKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAF 136 QGG FT + ++E G ++MA A ++ SQFFI A + Sbjct: 82 QGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMAN-AGPNTNGSQFFICTAKTEW 140 Query: 137 LDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 LD + VFGKV +GM++ + + + G SK + I L Sbjct: 141 LD-----GKHVVFGKVKEGMNIVEAMER-----FGSRNGKTSKKITIADCGQL 183 >5YB9-A nrPDB Length = 175 Score = 180 bits (456), Expect = 4e-46, Method: Composition-based stats. Identities = 44/167 (26%), Positives = 65/167 (38%), Gaps = 24/167 (14%) Query: 36 SAGNIELELDKQKAPVSVQNFVDYVNSG----------FYNNTTFHRVIPGFMIQGGGFT 85 G I EL P + +NF Y T FHR+IP FMIQGG FT Sbjct: 19 KVGKIVFELFNDIVPKTAENFRALCTGEKGIGKSGMPLSYKGTMFHRIIPQFMIQGGDFT 78 Query: 86 ---EQMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQR 142 + +E + G ++MA A ++ SQFFI + +LD Sbjct: 79 RFNGTGGESIYGMKFDDENFKVKHDKPGLLSMAN-AGPNTNGSQFFITTVETPWLD---- 133 Query: 143 DFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 + VFG+V++GMD+ +I T P ++ + Sbjct: 134 -GHHCVFGQVIEGMDIVKQIESCGTES-----GRPRAMCMVTDCGEM 174 >1C5F-A nrPDB Length = 177 Score = 179 bits (455), Expect = 4e-46, Method: Composition-based stats. Identities = 55/186 (29%), Positives = 77/186 (41%), Gaps = 29/186 (15%) Query: 23 MAAKGDPHVLLTTS-----AGNIELELDKQKAPVSVQNFVDYVNSG-----------FYN 66 M+ K V L + AG I +EL AP + NF+ Y Sbjct: 1 MSKKDRRRVFLDVTIDGNLAGRIVMELYNDIAPRTCNNFLMLCTGMAGTGKISGKPLHYK 60 Query: 67 NTTFHRVIPGFMIQGGGFTEQMQQKKPNPP---IKNEADNGLRNTRGTIAMARTADKDSA 123 +TFHRVI FMIQGG FT+ + +E + ++MA ++ Sbjct: 61 GSTFHRVIKNFMIQGGDFTKGDGTGGESIYGGMFDDEEFVMKHDEPFVVSMANK-GPNTN 119 Query: 124 TSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVI 183 SQFFI L++ + VFGKVV G +V KI + T+ +N P VVI Sbjct: 120 GSQFFITTTPAPHLNN-----IHVVFGKVVSGQEVVTKIEYLKTNS----KNRPLADVVI 170 Query: 184 LSAKVL 189 L+ L Sbjct: 171 LNCGEL 176 >3ICH-A nrPDB Length = 188 Score = 179 bits (455), Expect = 5e-46, Method: Composition-based stats. Identities = 54/182 (29%), Positives = 74/182 (40%), Gaps = 25/182 (13%) Query: 21 AAMAAKGDPHVLL---------TTSAGNIELELDKQKAPVSVQNFVDYVNSG---FYNNT 68 + K P V + G + L + P +V NFV Y N+ Sbjct: 4 GSDEKKKGPKVTVKVYFDLRIGDEDVGRVIFGLFGKTVPKTVDNFVALATGEKGFGYKNS 63 Query: 69 TFHRVIPGFMIQGGGFTEQMQQKKPNPP---IKNEADNGLRNTRGTIAMARTADKDSATS 125 FHRVI FMIQGG FT + +E G ++MA A KD+ S Sbjct: 64 KFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMAN-AGKDTNGS 122 Query: 126 QFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILS 185 QFFI A+LD + VFGKV++GM+V K+ T ++ P K V+I Sbjct: 123 QFFITTVKTAWLD-----GKHVVFGKVLEGMEVVRKVESTKTDS----RDKPLKDVIIAD 173 Query: 186 AK 187 Sbjct: 174 CG 175 >5TA2-A nrPDB Length = 163 Score = 179 bits (455), Expect = 5e-46, Method: Composition-based stats. Identities = 48/173 (27%), Positives = 71/173 (41%), Gaps = 22/173 (12%) Query: 28 DPHVLLTTS-----AGNIELELDKQKAPVSVQNFVDYVNSG---FYNNTTFHRVIPGFMI 79 +P V + G + EL K P + +NF Y + FHR+IPGFM Sbjct: 2 NPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMC 61 Query: 80 QGGGFTEQMQQKKPNPP---IKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAF 136 QGG FT + ++E G ++MA A ++ SQFFI A + Sbjct: 62 QGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMAN-AGPNTNGSQFFICTAKTEW 120 Query: 137 LDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 LD + VFGKV +GM++ + + + G SK + I L Sbjct: 121 LD-----GKHVVFGKVKEGMNIVEAMER-----FGSRNGKTSKKITIADCGQL 163 >4R3E-A nrPDB Length = 180 Score = 179 bits (454), Expect = 6e-46, Method: Composition-based stats. Identities = 59/171 (34%), Positives = 88/171 (51%), Gaps = 16/171 (9%) Query: 24 AAKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGG 83 + VLL T+AG+I++EL ++AP + +NF+ +Y+NT FHRV+PGF++QGG Sbjct: 10 EPPTNGKVLLKTTAGDIDIELWSKEAPKACRNFIQLCLEAYYDNTIFHRVVPGFIVQGGD 69 Query: 84 FTEQ--MQQKKPNPPIKNEADNGLR-NTRGTIAMARTADKDSATSQFFINVADNAFLDHG 140 T + P K+E + LR N RG +AMA D SQFF + L++ Sbjct: 70 PTGTGSGGESIYGAPFKDEFHSRLRFNRRGLVAMANAGSHD-NGSQFFFTLGRADELNN- 127 Query: 141 QRDFGYAVFGKVVKGMDVAD--KISQVPTHDVGPYQNVPSKPVVILSAKVL 189 + +FGKV G V + ++S+V D P P I S +VL Sbjct: 128 ----KHTIFGKVT-GDTVYNMLRLSEVDIDD----DERPHNPHKIKSCEVL 169 >2HE9-A nrPDB Length = 192 Score = 179 bits (454), Expect = 7e-46, Method: Composition-based stats. Identities = 46/187 (24%), Positives = 70/187 (37%), Gaps = 29/187 (15%) Query: 22 AMAAKGDPHVLLTTS-----AGNIELELDKQKAPVSVQNFVDYVNSG-----------FY 65 + +G P G I +L P + +NF+ + Y Sbjct: 13 GLVPRGSPQCHFDIEINREPVGRIMFQLFSDICPKTCKNFLCLCSGEKGLGKTTGKKLCY 72 Query: 66 NNTTFHRVIPGFMIQGGGFTEQ---MQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDS 122 +TFHRV+ FMIQGG F+E + K+E + ++MA K + Sbjct: 73 KGSTFHRVVKNFMIQGGDFSEGNGKGGESIYGGYFKDENFILKHDRAFLLSMANR-GKHT 131 Query: 123 ATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVV 182 SQFFI LD + VFG V+ G +V ++I + T P V Sbjct: 132 NGSQFFITTKPAPHLD-----GVHVVFGLVISGFEVIEQIENLKTDAAS----RPYADVR 182 Query: 183 ILSAKVL 189 ++ VL Sbjct: 183 VIDCGVL 189 >2HQJ-A nrPDB Length = 183 Score = 179 bits (454), Expect = 7e-46, Method: Composition-based stats. Identities = 52/191 (27%), Positives = 79/191 (41%), Gaps = 35/191 (18%) Query: 20 PAAMAAKGDPHVLLTTS-----AGNIELELDKQKAPVSVQNFVDYVNSG----------F 64 P +M +P V S AG I +EL P + +NF Sbjct: 2 PGSM---TNPKVFFDISIDNKAAGRIVMELYADTVPKTAENFRALCTGEKGKGRSGKPLH 58 Query: 65 YNNTTFHRVIPGFMIQGGGFTEQMQQKKPNPP---IKNEADNGL---RNTRGTIAMARTA 118 Y ++ FHRVIP FMIQGG FT + ++E+ +G G ++MA A Sbjct: 59 YKSSVFHRVIPNFMIQGGDFTRGNGTGGESIYGTTFRDESFSGKAGRHTGLGCLSMAN-A 117 Query: 119 DKDSATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPS 178 ++ SQFFI A +LD + VFG+V+ G+DV K+ ++ G Sbjct: 118 GPNTNGSQFFICTAATPWLD-----GKHVVFGRVIDGLDVVKKVERL-----GSSSGKTR 167 Query: 179 KPVVILSAKVL 189 +V+ + Sbjct: 168 SRIVVSDCGEV 178 >4EYV-A nrPDB Length = 167 Score = 178 bits (451), Expect = 1e-45, Method: Composition-based stats. Identities = 53/174 (30%), Positives = 77/174 (44%), Gaps = 22/174 (12%) Query: 27 GDPHVLLTT-----SAGNIELELDKQKAPVSVQNFVDYVN---SGFYNNTTFHRVIPGFM 78 P+V +AG I +L P++ +NF + Y +TFHR+IP FM Sbjct: 5 SQPNVYFDISIDNQNAGRIVFKLYDDVVPLTAKNFRELAKNPAGQGYTGSTFHRIIPQFM 64 Query: 79 IQGGGFTEQMQQKKPNPP---IKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNA 135 +QGG FT + K+E G ++MA A + SQFFI + Sbjct: 65 LQGGDFTNHNGTGGRSIYGNKFKDENFQLKHTKPGLLSMAN-AGPHTNGSQFFITTVVTS 123 Query: 136 FLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 +LD + VFG+VV+GMDV K+ V T PSK V I ++ + Sbjct: 124 WLD-----GKHVVFGEVVEGMDVVKKVEAVGTQS-----GKPSKVVKITASGTV 167 >2FU0-A nrPDB Length = 160 Score = 177 bits (449), Expect = 2e-45, Method: Composition-based stats. Identities = 44/166 (26%), Positives = 78/166 (46%), Gaps = 11/166 (6%) Query: 25 AKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGF 84 ++ T+ G+I + L ++ +VQNF + +G+YNN FHRVI FM+Q G Sbjct: 2 KNTPKSAIIYTTMGDIHISLFYKECKKTVQNFSVHSINGYYNNCIFHRVIKHFMVQTGDP 61 Query: 85 T--EQMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQR 142 + + ++E + L +++ + ++ SQFFI +LD Sbjct: 62 SGDGTGGESIWGNEFEDEFFDHLNHSKPFMVSMANCGPNTNGSQFFITTVPCPWLD---- 117 Query: 143 DFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKV 188 F + VFGKV +G + I +V T ++ P + + IL+ K+ Sbjct: 118 -FKHTVFGKVTQGSKIVLDIEKVRTD----KRDKPLEDIKILNIKI 158 >1XQ7-A nrPDB Length = 166 Score = 176 bits (446), Expect = 5e-45, Method: Composition-based stats. Identities = 52/161 (32%), Positives = 70/161 (43%), Gaps = 15/161 (9%) Query: 34 TTSAGNIELELDKQKAPVSVQNFVDYVNSG---FYNNTTFHRVIPGFMIQGGGFTEQMQQ 90 G + + L P +V+NF + Y + FHRVI FMIQGG FT Sbjct: 16 DEPVGRVVIGLFGNDVPKTVENFKQLASGENGFGYKGSIFHRVIRNFMIQGGDFTNFDGT 75 Query: 91 KKPNPPIKNEADNGL--RNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAV 148 + D L ++ G ++MA A +S SQFF+ A +LD + V Sbjct: 76 GGKSIYGTRFDDENLKIKHFVGAVSMAN-AGPNSNGSQFFVTTAPTPWLD-----GRHVV 129 Query: 149 FGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 FGKVV+GMDV K+ T + P K V I VL Sbjct: 130 FGKVVEGMDVVKKVENTKTG----LNDKPKKAVKINDCGVL 166 >2CFE-A nrPDB Length = 162 Score = 175 bits (443), Expect = 1e-44, Method: Composition-based stats. Identities = 50/186 (26%), Positives = 69/186 (37%), Gaps = 31/186 (16%) Query: 9 MAAVFALSALSPAAMAAKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSG---FY 65 M+ VF G P G I+ +L P + NF Y Sbjct: 1 MSNVFFDI-------TKNGAP-------LGTIKFKLFDDVVPKTAANFRALCTGEKGFGY 46 Query: 66 NNTTFHRVIPGFMIQGGGFTEQMQQKKPNPP---IKNEADNGLRNTRGTIAMARTADKDS 122 + FHRVIP FM+QGG FT + +E N G ++MA A ++ Sbjct: 47 AGSHFHRVIPDFMLQGGDFTAGNGTGGKSIYGAKFADENFQLKHNKPGLLSMAN-AGPNT 105 Query: 123 ATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVV 182 SQFFI ++LD + VFG+V+ GM+V I G P + Sbjct: 106 NGSQFFITTVVTSWLD-----GKHVVFGEVIDGMNVVKAIE-----AEGSGSGKPRSRIE 155 Query: 183 ILSAKV 188 I V Sbjct: 156 IAKCGV 161 >2B71-A nrPDB Length = 196 Score = 175 bits (443), Expect = 1e-44, Method: Composition-based stats. Identities = 50/159 (31%), Positives = 79/159 (49%), Gaps = 13/159 (8%) Query: 29 PHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQM 88 ++ + T+ G+ E+EL +P + NF GFY+NT FHRVIP F+IQGG T Sbjct: 39 GYITIYTNLGDFEVELYWYHSPKTCLNFYTLCEMGFYDNTIFHRVIPNFVIQGGDPTGTG 98 Query: 89 QQKK--PNPPIKNEADNGLRNTR-GTIAMARTADKDSATSQFFINVADNAFLDHGQRDFG 145 + K ++E + L++T G ++M+ ++ +SQFFI +A LD Sbjct: 99 KGGKSIYGEYFEDEINKELKHTGAGILSMSNN-GPNTNSSQFFITLAPLPHLD-----GK 152 Query: 146 YAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVIL 184 + +F +V K M + I+ V T N P + IL Sbjct: 153 HTIFARVSKNMTCIENIASVQT----TATNKPIFDLKIL 187 >1Z81-A nrPDB Length = 229 Score = 174 bits (440), Expect = 3e-44, Method: Composition-based stats. Identities = 44/180 (24%), Positives = 71/180 (39%), Gaps = 23/180 (12%) Query: 26 KGDPHVLLTTSAGN-----IELELDKQKAPVSVQNFVDYVNSGF--------YNNTTFHR 72 +P V + + GN + EL + P + +NF + + Y NT FHR Sbjct: 57 PSNPVVFMDINLGNNFLGKFKFELFQNIVPKTSENFRQFCTGEYKVNNLPVGYKNTIFHR 116 Query: 73 VIPGFMIQGGGFTEQMQQK---KPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFI 129 VI FMIQGG F +E + + G ++MA + ++ QFFI Sbjct: 117 VIKEFMIQGGDFINHNGSGSLSIYGEKFDDENFDIKHDKEGLLSMANS-GPNTNGCQFFI 175 Query: 130 NVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 +LD VFG+++ D + ++ V PY P P+ ++ L Sbjct: 176 TTKKCEWLDGKN-----VVFGRIIDN-DSLLLLKKIENVSVTPYIYKPKIPINVVECGEL 229 >2QER-A nrPDB Length = 185 Score = 173 bits (438), Expect = 4e-44, Method: Composition-based stats. Identities = 46/162 (28%), Positives = 77/162 (47%), Gaps = 12/162 (7%) Query: 31 VLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQMQQ 90 V + T+ G+++ EL + P + +NF+ SG+Y NT FH+ I GF+IQGG T + Sbjct: 19 VRIITNYGDLKFELFCSQCPKACKNFLALSASGYYKNTIFHKNIKGFIIQGGDPTGTGKG 78 Query: 91 K--KPNPPIKNEADNGLR-NTRGTIAMARTAD---KDSATSQFFINVADNAFLDHGQRDF 144 +E L+ + RG ++MA ++ SQFFI + L+ Sbjct: 79 GESIYGRYFDDEIYPELKYDRRGILSMASKGASKKPNTNGSQFFITYSSLPQLN-----G 133 Query: 145 GYAVFGKVVKGMDVADKISQVPTHDV-GPYQNVPSKPVVILS 185 Y +FGK++ G + + + P+ P + K +VI S Sbjct: 134 EYVIFGKLIDGFETLNTLENCPSDKSHKPIDEIIIKDIVIHS 175 >3PMP-A nrPDB Length = 164 Score = 171 bits (434), Expect = 1e-43, Method: Composition-based stats. Identities = 47/188 (25%), Positives = 76/188 (40%), Gaps = 31/188 (16%) Query: 8 AMAAVFALSALSPAAMAAKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGF--- 64 AMA VF +++ G I +L + P + +NF + Sbjct: 1 AMANVFFNISIN--------------DKPEGRIVFKLYDEAVPKTAKNFRELATGQHGFG 46 Query: 65 YNNTTFHRVIPGFMIQGGGFTEQMQQKKPNPPIKNEADNGL---RNTRGTIAMARTADKD 121 Y ++ FHRVIP FM+QGG FT + + AD G ++MA A + Sbjct: 47 YKDSIFHRVIPQFMLQGGDFTRHNGTGGKSIYGEKFADENFQVKHTKPGLLSMAN-AGAN 105 Query: 122 SATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPV 181 + SQFFI ++LD + VFG+V++G+D+ K+ G + + Sbjct: 106 TNGSQFFITTVPTSWLD-----GKHVVFGEVIEGLDIVRKVE-----GKGSASGKTNATI 155 Query: 182 VILSAKVL 189 I + Sbjct: 156 KITDCGTV 163 >1H0P-A nrPDB Length = 182 Score = 171 bits (434), Expect = 1e-43, Method: Composition-based stats. Identities = 50/174 (28%), Positives = 72/174 (41%), Gaps = 21/174 (12%) Query: 25 AKGDPHVLLT-----TSAGNIELELDKQKAPVSVQNFVDYVN---SGFYNNTTFHRVIPG 76 K V G I + L + P + NF++ Y + FHRVI Sbjct: 3 PKVTDRVYFDMEIGGKPIGRIVIGLFGKTVPKTATNFIELAKKPKGEGYPGSKFHRVIAD 62 Query: 77 FMIQGGGFTEQMQQKKPNPPIKNEADNGLRNTR---GTIAMARTADKDSATSQFFINVAD 133 FMIQGG FT + + AD + G ++MA A D+ SQFFI Sbjct: 63 FMIQGGDFTRGDGTGGRSIYGEKFADENFKLKHYGAGWLSMAN-AGADTNGSQFFITTVK 121 Query: 134 NAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAK 187 +LD + VFGK+++GMDV KI Q + P + V+I ++ Sbjct: 122 TPWLD-----GRHVVFGKILEGMDVVRKIEQTEKLPG----DRPKQDVIIAASG 166 >2RMC-A nrPDB Length = 182 Score = 170 bits (431), Expect = 3e-43, Method: Composition-based stats. Identities = 47/160 (29%), Positives = 66/160 (41%), Gaps = 16/160 (10%) Query: 34 TTSAGNIELELDKQKAPVSVQNFVDYVNSG---FYNNTTFHRVIPGFMIQGGGFTEQMQQ 90 G I + L P +V+NFV Y + FHRVI FMIQGG FT + Sbjct: 18 DKDVGRIVIGLFGNVVPKTVENFVALATGEKGYGYKGSIFHRVIKDFMIQGGDFTARDGT 77 Query: 91 KKPNPPIKNEADNGLRNTR---GTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYA 147 + + D + G ++MA A D+ SQFFI + +LD + Sbjct: 78 GGMSIYGETFPDENFKLKHYGIGWVSMAN-AGPDTNGSQFFITLTKPTWLD-----GKHV 131 Query: 148 VFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAK 187 VFGKV+ GM V I T + P I+++ Sbjct: 132 VFGKVLDGMTVVHSIELQATDG----HDRPLTDCTIVNSG 167 >2ESL-A nrPDB Length = 190 Score = 167 bits (422), Expect = 3e-42, Method: Composition-based stats. Identities = 46/160 (28%), Positives = 65/160 (40%), Gaps = 16/160 (10%) Query: 34 TTSAGNIELELDKQKAPVSVQNFVDYVNSG---FYNNTTFHRVIPGFMIQGGGFTEQMQQ 90 G I + L + P +V+NFV Y + FHRVI FMIQGG T Sbjct: 26 DKDVGRIVIGLFGKVVPKTVENFVALATGEKGYGYKGSKFHRVIKDFMIQGGDITTGDGT 85 Query: 91 KKPNPPIKNEADNGLRNTR---GTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYA 147 + + D + G ++MA A D+ SQFFI + +LD + Sbjct: 86 GGVSIYGETFPDENFKLKHYGIGWVSMAN-AGPDTNGSQFFITLTKPTWLD-----GKHV 139 Query: 148 VFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAK 187 VFGKV+ GM V I T + P I+++ Sbjct: 140 VFGKVIDGMTVVHSIELQATDG----HDRPLTNCSIINSG 175 >4R3F-A nrPDB Length = 204 Score = 165 bits (418), Expect = 9e-42, Method: Composition-based stats. Identities = 46/195 (23%), Positives = 85/195 (43%), Gaps = 34/195 (17%) Query: 23 MAAKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGG 82 + + V++ T+ G++++EL ++ P++ +NF+ + G+Y+ T FHR++PGF+IQGG Sbjct: 10 LEPQPTGAVIIHTTQGDLKVELFAKQTPLTCRNFLQHSLDGYYDGTIFHRLVPGFIIQGG 69 Query: 83 GFTEQMQQKKP---------------------------NPPIKNEADNGLR-NTRGTIAM 114 T + K+E + L+ N RG + M Sbjct: 70 DPTGTGHGGESIYDGGAFSGDLDPWPMDQRKGHNAGPMGVNFKDEFHSRLKFNRRGLLGM 129 Query: 115 ARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQ 174 A D+ SQFF + L++ +FG+V G D + + ++ Sbjct: 130 ANEGAPDTNGSQFFFTLGKAEELNNKN-----TLFGRVAAG-DTIYNLMKWGEAELIEGT 183 Query: 175 NVPSKPVVILSAKVL 189 P PV I + ++L Sbjct: 184 ERPQYPVKITNIEIL 198 >4I9Y-A nrPDB Length = 167 Score = 159 bits (402), Expect = 8e-40, Method: Composition-based stats. Identities = 43/174 (24%), Positives = 65/174 (37%), Gaps = 22/174 (12%) Query: 27 GDPHVLLT-----TSAGNIELELDKQKAPVSVQNFVDYVNSG---FYNNTTFHRVIPGFM 78 +P V G I +EL P + +NF + N+ FHRVIP F+ Sbjct: 5 TNPVVFFDVCADGEPLGRITMELFSNIVPRTAENFRALCTGEKGFGFKNSIFHRVIPDFV 64 Query: 79 IQGGGFTEQMQQKK---PNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNA 135 QGG T+ ++E + G ++MA +++ SQF I + Sbjct: 65 CQGGDITKHDGTGGQSIYGDKFEDENFDVKHTGPGLLSMANQ-GQNTNNSQFVITLKKAE 123 Query: 136 FLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 LD F + VFG V GMD KI G + + + I + Sbjct: 124 HLD-----FKHVVFGFVKDGMDTVKKIE-----SFGSPKGSVCRRITITECGQI 167 >6HIX-BQ nrPDB Length = 231 Score = 153 bits (386), Expect = 5e-38, Method: Composition-based stats. Identities = 49/179 (27%), Positives = 75/179 (41%), Gaps = 28/179 (15%) Query: 28 DPHVLLTTS-----AGNIELELDKQKAPVSVQNFVDYVNSG--------FYNNTTFHRVI 74 +P V + + G + +EL P + +NF FY FHRVI Sbjct: 28 NPVVFMDVTVEGDALGRVSVELFHDIVPKTTENFRSLCTGERGYSQCPLFYKGIPFHRVI 87 Query: 75 PGFMIQGGGFT---EQMQQKKPNPPIKNEADNGL--RNTRGTIAMARTADKDSATSQFFI 129 PGF++QGG + P +E+ G ++ RGT+AMA +A + SQFF Sbjct: 88 PGFIVQGGDILLKDGRGNVSVFGFPFPDESFEGKAGKHLRGTVAMAHSA-PNQNGSQFFF 146 Query: 130 NVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKV 188 N+A N LD + V G+V+ G +V D+++ + G P I Sbjct: 147 NLARNDHLD-----GKFVVCGQVIDGWEVVDRVAVLSGSSCGT----PVSRAWITECGQ 196 >1W74-A nrPDB Length = 191 Score = 149 bits (376), Expect = 8e-37, Method: Composition-based stats. Identities = 50/174 (28%), Positives = 70/174 (40%), Gaps = 27/174 (15%) Query: 32 LLTTSAGNIELELDKQKAPVSVQNFVDYVNSG---------------FYNNTTFHRVIPG 76 L T+ G+I++ L AP +V NFV FY+ FHRVI G Sbjct: 27 TLHTNRGDIKIALFGNHAPKTVANFVGLAQGTKDYSTQNASGGPSGPFYDGAVFHRVIQG 86 Query: 77 FMIQGGGFTEQMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAF 136 FMIQGG T + + +AMA A + SQFFI V Sbjct: 87 FMIQGGDPTGTGRGGPGYKFADEFHPELQFDKPYLLAMAN-AGPGTNGSQFFITVGKTPH 145 Query: 137 LDHGQRDFGYAVFGKVVK--GMDVADKISQVPTHDVGPYQNVPSKPVVILSAKV 188 L+ + +FG+V+ V + IS+ T + P+ PVVI S + Sbjct: 146 LNR-----RHTIFGEVIDAESQRVVEAISKTATDG----NDRPTDPVVIESITI 190 >3BO7-A nrPDB Length = 201 Score = 149 bits (375), Expect = 8e-37, Method: Composition-based stats. Identities = 44/157 (28%), Positives = 74/157 (47%), Gaps = 21/157 (13%) Query: 26 KGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFT 85 K ++ + T+ G++ +EL AP + +F+ ++++T FHR I FMIQGG Sbjct: 4 KKKGYLRIVTTQGSLNIELHADMAPRACDSFLRLCAVKYFDDTIFHRCIRNFMIQGGRAE 63 Query: 86 EQMQQKKP--------------NPPIKNEADNGLRNTR-GTIAMARTADKDSATSQFFIN 130 + KK P ++E DN L + G ++MA K S S+FFI Sbjct: 64 LRQPSKKKEVQQSPRSISGFPGGAPFEDEFDNRLVHQGIGVLSMAND-GKHSNLSEFFIT 122 Query: 131 VADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPT 167 L++ + +FG+VV G+DV + ++ T Sbjct: 123 FKSCEHLNN-----KHTIFGRVVGGLDVLRQWEKLET 154 >2MVZ-A nrPDB Length = 148 Score = 145 bits (366), Expect = 1e-35, Method: Composition-based stats. Identities = 57/158 (36%), Positives = 73/158 (46%), Gaps = 11/158 (6%) Query: 21 AAMAAKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQ 80 +MA KG +L + G IE EL +APV+V NF N GFYN TFHRVIPGF+ Q Sbjct: 1 GSMAKKG---YILMENGGKIEFELFPNEAPVTVANFEKLANEGFYNGLTFHRVIPGFVSQ 57 Query: 81 GGGFTEQMQQKKPNPPIKNEADNG-LRNTRGTIAMARTADKDSATSQFFINVADNAFLDH 139 GG I E DN R+ G ++MA +D+ + QFFI LD Sbjct: 58 GGCP-RGNGTGDAGYTIPCETDNNPHRHVTGAMSMAHR-GRDTGSCQFFIVHEPQPHLD- 114 Query: 140 GQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVP 177 + VFG+V GMDV + + P Sbjct: 115 ----GVHTVFGQVTSGMDVVRTMKNGDVMKEVKVFDEP 148 >6HIX-BZ nrPDB Length = 190 Score = 143 bits (360), Expect = 5e-35, Method: Composition-based stats. Identities = 51/184 (27%), Positives = 75/184 (40%), Gaps = 37/184 (20%) Query: 34 TTSAGNIELELDKQKAPVSVQNFVDYVNSGF-----------------------YNNTTF 70 T + I +L +K P +V+NF++ + Y N+TF Sbjct: 15 TKAPRRIVFKLFPRKCPSAVKNFIELCSGNVSTDTYESGNRDKLISESALPQLTYKNSTF 74 Query: 71 HRVIPGFMIQGGGF-----TEQMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATS 125 HRV G++IQGG TEQ+ E + + G + A ++ ++ S Sbjct: 75 HRVEKGYLIQGGDIVTGRGTEQLSIYGGTFSAPEEVRASVFDKPGLVGTA-SSSPNAHGS 133 Query: 126 QFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILS 185 QFFI A A +G FG+V G+DV +I QVP G PS V I+ Sbjct: 134 QFFILTAKEANHLNGT----CICFGQVADGLDVVQEIEQVPIDPSG----FPSLKVSIVD 185 Query: 186 AKVL 189 VL Sbjct: 186 CGVL 189 >5EX1-A nrPDB Length = 283 Score = 141 bits (355), Expect = 2e-34, Method: Composition-based stats. Identities = 52/199 (26%), Positives = 84/199 (42%), Gaps = 45/199 (22%) Query: 26 KGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFT 85 + + V++TT G+I +EL+ + AP V F D V + YN F+RVI GF+ QGG Sbjct: 35 EPENIVVITTKYGDILIELNPEFAPGHVARFQDMVKARAYNGKEFYRVIDGFVAQGGIDA 94 Query: 86 EQMQQKKPNPPIKNEAD------------------------------------NGLRNTR 109 E K PP++ E + L + Sbjct: 95 ED----KKWPPLEIEHEQPLLEADQIQLLDNDDLFAEKVGFLNGFPVGFDAEKKWLLHCP 150 Query: 110 GTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHD 169 G +AMAR +D ++ + F+I + +LD VFG+V+ GM K+ + + Sbjct: 151 GMLAMARDSDPNTGGTDFYITLDAQRYLDRN-----MTVFGRVISGMQYVQKLQRGDKNI 205 Query: 170 VGPYQNVPSKPVVILSAKV 188 G P+K ++S K+ Sbjct: 206 EGGVIQSPNKGDEMISVKL 224 >5JHE-A nrPDB Length = 397 Score = 140 bits (354), Expect = 3e-34, Method: Composition-based stats. Identities = 47/203 (23%), Positives = 66/203 (32%), Gaps = 52/203 (25%) Query: 28 DPHVLLTTSA-----GNIELELDKQKAPVSVQNFVDYVNSGF-----------YNNTTFH 71 DP V L S G I +L ++KAP + +NF Y FH Sbjct: 8 DPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFH 67 Query: 72 RVIPGFMIQGGGFT--------------------------EQMQQKKPNPPIKNEADNGL 105 RV+ FMIQ G + + ++E + G Sbjct: 68 RVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDE-NLGE 126 Query: 106 RNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQV 165 T+ MA ++ SQFFI L+ +++FG+VV G V I Sbjct: 127 FVEPFTLGMANLGSPNTNNSQFFITTYAAPHLN-----GKHSIFGQVVHGKSVVRTIENC 181 Query: 166 PTHDVGPYQNVPSKPVVILSAKV 188 G VP V I V Sbjct: 182 RVDSDG----VPESDVRISDCGV 200 >3BKP-A nrPDB Length = 232 Score = 135 bits (340), Expect = 1e-32, Method: Composition-based stats. Identities = 51/181 (28%), Positives = 81/181 (44%), Gaps = 26/181 (14%) Query: 27 GDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTE 86 V+L TS G++++EL ++ P++ +NFV G+Y NT FHRV+ F++QGG T Sbjct: 20 TRGKVVLHTSLGDLDVELWARECPLACRNFVQLCLEGYYVNTIFHRVVKDFIVQGGDPTG 79 Query: 87 QMQQK----KPNPPIKNEADNGLRNT-RGTIAMAR------TADKD-------SATSQFF 128 + P E L+ RG + +A A+ D + +QFF Sbjct: 80 TGRGGADTTFDGKPFDVETHPRLKFRYRGLVGVANLGRSSKDAENDERGRSLGTNGNQFF 139 Query: 129 INVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVPSKPVVILSAKV 188 I +A L++ Y +FGKV + + +VG ++ P P I S V Sbjct: 140 ITLARADVLNNA-----YTLFGKVTG--HTLYNLMKFNDLEVG-KEDRPMTPPFIKSVDV 191 Query: 189 L 189 L Sbjct: 192 L 192 >5EX2-A nrPDB Length = 271 Score = 126 bits (317), Expect = 5e-30, Method: Composition-based stats. Identities = 50/211 (23%), Positives = 82/211 (38%), Gaps = 63/211 (29%) Query: 28 DPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGG---- 83 D V+ T+ G + +EL + AP V V +G Y+ T FHRVI GFM QGG Sbjct: 23 DNLVIFETTKGVVYIELAPEIAPNHVAQIRKVVRTGLYSGTKFHRVISGFMAQGGDIAAT 82 Query: 84 ---------------------------------------------FTEQMQQKKPNPPIK 98 E Q + N Sbjct: 83 LGREPDLEAVDGEFVFRRDPKSIVLTVINEEDQTKSQYTGFYNGFPIETRQDELANYSED 142 Query: 99 NEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDV 158 ++ + + G ++MART D +S QFF+ ++ FLD Y+ +G++++G+DV Sbjct: 143 KRVESWMPHCAGVVSMARTNDPNSGKDQFFLMRDESRFLDR-----KYSSWGRMLEGLDV 197 Query: 159 ADKISQVPTHDVGPYQNVPSKPVVILSAKVL 189 A + P +P +++SA ++ Sbjct: 198 AKSL---------TIGEPPERPDILVSAVMV 219 >3RFY-A nrPDB Length = 369 Score = 92.8 bits (229), Expect = 8e-20, Method: Composition-based stats. Identities = 43/156 (27%), Positives = 59/156 (37%), Gaps = 34/156 (21%) Query: 39 NIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGG-------FTEQMQQK 91 I LD APV+ NFVD V FY+ R GF++Q G F + +K Sbjct: 191 RIV--LDGYNAPVTAGNFVDLVERHFYDGMEIQRS-DGFVVQTGDPEGPAEGFIDPSTEK 247 Query: 92 KPNPPIK-------------NEADNGLR--------NTRGTIAMARTA-DKDSATSQFFI 129 P++ + GL N GT+AMAR + DS +SQ F Sbjct: 248 TRTVPLEIMVTGEKTPFYGSTLEELGLYKAQVVIPFNAFGTMAMAREEFENDSGSSQVFW 307 Query: 130 NVADNAFLDHGQR--DFGYAVFGKVVKGMDVADKIS 163 + ++ D YAVFG V D + Sbjct: 308 LLKESELTPSNSNILDGRYAVFGYVTDNEDFLADLK 343 >2OSE-A nrPDB Length = 234 Score = 61.2 bits (147), Expect = 2e-10, Method: Composition-based stats. Identities = 37/198 (18%), Positives = 59/198 (29%), Gaps = 43/198 (21%) Query: 27 GDPHVLLTTSA-----GNIELELDKQKAPVSVQNFVDYVNSGFYN--------------- 66 +P V + G ++++L + P V+NFV N Y Sbjct: 13 KNPRVYMDIVLNNEIIGRLQIKLFRDAFPAGVENFVQLTNGKTYRVNSNGTGKYKYNRHI 72 Query: 67 -----NTTFHRVIPGFMIQGGGFTEQMQQKKPNPPIKNEADNGL------RNTRGTIAMA 115 FH V+ I G ++G +++ Sbjct: 73 NRTYEGCKFHNVLHNNYIVSGDIYNSNGSSAGTVYCDEPIPPVFGDYFYPHESKGLLSLV 132 Query: 116 RTADKDSAT---SQFFINVA---DNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHD 169 D+ S F I + + LD RD V G+V G+DV DKI+ + Sbjct: 133 PYTDESGNRYYDSTFMITLDDIRPSNVLDELDRDQ--VVIGQVYGGLDVLDKINSM---- 186 Query: 170 VGPYQNVPSKPVVILSAK 187 + PY I Sbjct: 187 IKPYAGRKYPTFSIGKCG 204 >5GM6-b nrPDB Length = 301 Score = 56.6 bits (135), Expect = 6e-09, Method: Composition-based stats. Identities = 27/131 (20%), Positives = 49/131 (37%), Gaps = 14/131 (10%) Query: 23 MAAKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGG 82 + + +L T+ GNI +EL ++ P + + F+ ++ G + N F + P Q Sbjct: 5 IEPQTTAKCILYTTKGNIAIELWAKECPETCKRFLSMLSDGTFTNGEFKELKP---TQWL 61 Query: 83 GFTEQMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQR 142 F + + N G + R +++ +FI V D Sbjct: 62 MFNANSTGEYRTVAEEKNPRIRF-NRDGLLGWDRR--RNT----WFITVLA----DSKHV 110 Query: 143 DFGYAVFGKVV 153 VFGK+V Sbjct: 111 LNDCNVFGKIV 121 >2SIL-A nrPDB Length = 381 Score = 31.5 bits (70), Expect = 0.23, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 23/69 (33%), Gaps = 2/69 (2%) Query: 77 FMIQGGGFTEQMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAF 136 F Q G + ++GTI + A ++A+ Q FI+ A Sbjct: 15 FTDQKGNTIVGSGSGGTTKYFR--IPAMCTTSKGTIVVFADARHNTASDQSFIDTAAARS 72 Query: 137 LDHGQRDFG 145 D G+ Sbjct: 73 TDGGKTWNK 81 >2W1Z-A nrPDB Length = 368 Score = 27.7 bits (60), Expect = 2.9, Method: Composition-based stats. Identities = 9/50 (18%), Positives = 19/50 (38%), Gaps = 3/50 (6%) Query: 34 TTSAGNIELELDKQKAPVSV---QNFVDYVNSGFYNNTTFHRVIPGFMIQ 80 T G++ +E + P + +N N+ +T R F ++ Sbjct: 1 HTDPGDVVIEELFNRIPETSVWNENERVLSNANHLVSTALWRNEQSFRVE 50 >3HRI-A nrPDB Length = 456 Score = 27.7 bits (60), Expect = 3.3, Method: Composition-based stats. Identities = 7/28 (25%), Positives = 9/28 (32%), Gaps = 5/28 (17%) Query: 40 IELELDKQKAPVSVQNFVDYVNSGFYNN 67 I E + NF G Y+N Sbjct: 300 IVFEGFDRD-----GNFRALCGGGRYDN 322 >4H4F-A nrPDB Length = 249 Score = 27.7 bits (60), Expect = 3.4, Method: Composition-based stats. Identities = 8/51 (15%), Positives = 16/51 (31%) Query: 72 RVIPGFMIQGGGFTEQMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDS 122 RV + GG P+ + +NG G ++ ++ Sbjct: 166 RVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNT 216 >5ZWM-J nrPDB Length = 469 Score = 26.9 bits (58), Expect = 5.4, Method: Composition-based stats. Identities = 5/36 (13%), Positives = 16/36 (44%) Query: 26 KGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVN 61 K + L T+ G+I++++ + + ++ Sbjct: 401 KWNEDFELHTNTGDIKMDMHNNSISKTWEGYLQDCK 436 >4YHU-A nrPDB Length = 177 Score = 26.9 bits (58), Expect = 5.4, Method: Composition-based stats. Identities = 5/36 (13%), Positives = 16/36 (44%) Query: 26 KGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVN 61 K + L T+ G+I++++ + + ++ Sbjct: 109 KWNEDFELHTNTGDIKMDMHNNSISKTWEGYLQDCK 144 >4YHV-A nrPDB Length = 148 Score = 26.5 bits (57), Expect = 6.3, Method: Composition-based stats. Identities = 5/36 (13%), Positives = 16/36 (44%) Query: 26 KGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVN 61 K + L T+ G+I++++ + + ++ Sbjct: 80 KWNEDFELHTNTGDIKMDMHNNSISKTWEGYLQDCK 115 >4AQG-A nrPDB Length = 483 Score = 26.5 bits (57), Expect = 6.5, Method: Composition-based stats. Identities = 5/43 (11%), Positives = 8/43 (18%) Query: 5 TLAAMAAVFALSALSPAAMAAKGDPHVLLTTSAGNIELELDKQ 47 T ++ P + G EL Sbjct: 324 TFPTVSQFLFELGKQPRGTKKMKKALLSTPMKWGKKLYELFAD 366 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.137 0.410 Lambda K H 0.267 0.0424 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,614,635 Number of Sequences: 36641 Number of extensions: 314327 Number of successful extensions: 1216 Number of sequences better than 10.0: 78 Number of HSP's better than 10.0 without gapping: 143 Number of HSP's successfully gapped in prelim test: 8 Number of HSP's that attempted gapping in prelim test: 737 Number of HSP's gapped (non-prelim): 159 length of query: 190 length of database: 10,336,785 effective HSP length: 92 effective length of query: 98 effective length of database: 6,965,813 effective search space: 682649674 effective search space used: 682649674 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 56 (26.1 bits)