BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P0AFI2 (752 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1ZVU-A nrPDB 1464 0.0 5EIX-A nrPDB 970 0.0 6BQ9-A nrPDB 773 0.0 2XKJ-E nrPDB 691 0.0 1ZVT-A nrPDB 524 e-149 6QTP-A nrPDB 418 e-117 2XCO-A nrPDB 417 e-116 5BS3-B nrPDB 416 e-116 4DDQ-A nrPDB 403 e-112 3NUH-A nrPDB 376 e-104 6N1Q-A nrPDB 369 e-102 3LPX-A nrPDB 363 e-100 3IFZ-A nrPDB 357 1e-98 4KPF-A nrPDB 348 5e-96 2INR-A nrPDB 347 8e-96 4Z53-A nrPDB 347 1e-95 6CA8-A nrPDB 76 5e-14 1BJT-A nrPDB 69 9e-12 5GWJ-A nrPDB 62 6e-10 4ELZ-A nrPDB 62 8e-10 4FM9-A nrPDB 62 1e-09 4ELY-A nrPDB 53 5e-07 1X75-A nrPDB 51 2e-06 1K2W-A nrPDB 35 0.094 4E6P-A nrPDB 35 0.12 2VDU-B nrPDB 34 0.22 2PCN-A nrPDB 32 0.76 4TR2-A nrPDB 29 7.0 4G3N-A nrPDB 29 7.3 >1ZVU-A nrPDB Length = 716 Score = 1464 bits (3790), Expect = 0.0, Method: Compositional matrix adjust. Identities = 716/716 (100%), Positives = 716/716 (100%) Query: 27 MDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAM 86 MDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAM Sbjct: 1 MDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAM 60 Query: 87 VLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPN 146 VLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPN Sbjct: 61 VLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPN 120 Query: 147 FDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQL 206 FDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQL Sbjct: 121 FDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQL 180 Query: 207 LDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMRAVWKKEDGAVVISALPHQVSGARV 266 LDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMRAVWKKEDGAVVISALPHQVSGARV Sbjct: 181 LDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMRAVWKKEDGAVVISALPHQVSGARV 240 Query: 267 LEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTDLEKSYR 326 LEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTDLEKSYR Sbjct: 241 LEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTDLEKSYR 300 Query: 327 INLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNI 386 INLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNI Sbjct: 301 INLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNI 360 Query: 387 DEVIEIIRNEDEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQ 446 DEVIEIIRNEDEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQ Sbjct: 361 DEVIEIIRNEDEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQ 420 Query: 447 LQGILASERKMNNLLKKELQADAQAYGDDRRSPLQEREEAKAMSEHDMLPSEPVTIVLSQ 506 LQGILASERKMNNLLKKELQADAQAYGDDRRSPLQEREEAKAMSEHDMLPSEPVTIVLSQ Sbjct: 421 LQGILASERKMNNLLKKELQADAQAYGDDRRSPLQEREEAKAMSEHDMLPSEPVTIVLSQ 480 Query: 507 MGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITLPSARGQ 566 MGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITLPSARGQ Sbjct: 481 MGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITLPSARGQ 540 Query: 567 GEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPE 626 GEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPE Sbjct: 541 GEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPE 600 Query: 627 NAHVMPPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGL 686 NAHVMPPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGL Sbjct: 601 NAHVMPPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGL 660 Query: 687 AQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGERGRRGTLMRGLQRIDRVEIDSP 742 AQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGERGRRGTLMRGLQRIDRVEIDSP Sbjct: 661 AQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGERGRRGTLMRGLQRIDRVEIDSP 716 >5EIX-A nrPDB Length = 741 Score = 970 bits (2508), Expect = 0.0, Method: Compositional matrix adjust. Identities = 469/490 (95%), Positives = 482/490 (98%) Query: 1 MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKF 60 MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKF Sbjct: 246 MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKF 305 Query: 61 KKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRY 120 KKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPL DGQGNWGAPDDPKSFAAMRY Sbjct: 306 KKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLGDGQGNWGAPDDPKSFAAMRY 365 Query: 121 TESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDI 180 TESRLSKY+ELLLSELGQGT DWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDI Sbjct: 366 TESRLSKYAELLLSELGQGTVDWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDI 425 Query: 181 PPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR 240 PPHNLREVA+AAI LI+QPKTTLD+LLDIVQGPD+PTEAEIITSRAEIRKIY+NGRGSVR Sbjct: 426 PPHNLREVAKAAITLIEQPKTTLDELLDIVQGPDFPTEAEIITSRAEIRKIYQNGRGSVR 485 Query: 241 MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIV 300 MRAVW KEDGAVVI+ALPHQVSGA+VLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIV Sbjct: 486 MRAVWSKEDGAVVITALPHQVSGAKVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIV 545 Query: 301 PRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRR 360 PRSNRVDM+QVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRR Sbjct: 546 PRSNRVDMEQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRR 605 Query: 361 RLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPKPALMSRFGLTETQAEAILEL 420 RLN+RLEKVLKRLHILEGLLVAFLNIDEVIEIIR EDEPKPALMSRFG++ETQAEAILEL Sbjct: 606 RLNHRLEKVLKRLHILEGLLVAFLNIDEVIEIIRTEDEPKPALMSRFGISETQAEAILEL 665 Query: 421 KLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL 480 KLRHLAKLEEMKIRGEQSELEKERDQLQ ILASERKMNNLLKKELQADA A+GDDRRSPL Sbjct: 666 KLRHLAKLEEMKIRGEQSELEKERDQLQAILASERKMNNLLKKELQADADAFGDDRRSPL 725 Query: 481 QEREEAKAMS 490 EREEAKAMS Sbjct: 726 HEREEAKAMS 735 >6BQ9-A nrPDB Length = 496 Score = 773 bits (1995), Expect = 0.0, Method: Compositional matrix adjust. Identities = 365/484 (75%), Positives = 424/484 (87%) Query: 3 DMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKK 62 D ER +L +FTE AYLNYSMYVIMDRALP IGDGLKPVQRRIVYAMSELGL+A AK KK Sbjct: 13 DGVERRSLADFTEQAYLNYSMYVIMDRALPHIGDGLKPVQRRIVYAMSELGLDADAKHKK 72 Query: 63 SARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTE 122 SARTVGDVLGK+HPHGDSACYEAMVLMAQPFSYRY LVDGQGNWGAPDDPKSFAAMRYTE Sbjct: 73 SARTVGDVLGKFHPHGDSACYEAMVLMAQPFSYRYTLVDGQGNWGAPDDPKSFAAMRYTE 132 Query: 123 SRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPP 182 +RLS+Y+E+LLSE+GQGT DWVPNFDGTLQEP +LPARLPNILLNGTTGIAVGMATD+PP Sbjct: 133 ARLSRYAEVLLSEVGQGTVDWVPNFDGTLQEPAVLPARLPNILLNGTTGIAVGMATDVPP 192 Query: 183 HNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMR 242 HNLREVA A + L+D+PK T++QL + +QGPDYPTEAEI+T RAEI K+YE+GRGS+RMR Sbjct: 193 HNLREVASACVRLLDEPKATIEQLCEHIQGPDYPTEAEIVTPRAEILKMYESGRGSIRMR 252 Query: 243 AVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPR 302 AV++ EDG +V++ALPHQVSGA+VLEQIAAQM+ KKLPMV DLRDESDHENP R+VI+PR Sbjct: 253 AVYRVEDGDIVVTALPHQVSGAKVLEQIAAQMQAKKLPMVADLRDESDHENPCRIVIIPR 312 Query: 303 SNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRL 362 SNRVD+D++M HLFATTDLE +YR+N+N+IGLDGRP +KNL +L EWL FR +TVRRRL Sbjct: 313 SNRVDVDELMQHLFATTDLESTYRVNVNIIGLDGRPQLKNLRTLLVEWLEFRTNTVRRRL 372 Query: 363 NYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPKPALMSRFGLTETQAEAILELKL 422 +RL+KV KRLH+L+GLL AFLN+DEVI IIR E+ PK AL+ RF LTE QA+ ILE +L Sbjct: 373 QHRLDKVEKRLHLLDGLLTAFLNLDEVIHIIRTEEYPKQALIERFELTEIQADYILETRL 432 Query: 423 RHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPLQE 482 R LA+LEEMKIRGEQ EL KE+ +LQ +L SE K+ L++ EL DA+ YGDDRRSP+ Sbjct: 433 RQLARLEEMKIRGEQDELLKEQAKLQALLGSEAKLRKLVRSELIKDAETYGDDRRSPIVA 492 Query: 483 REEA 486 R EA Sbjct: 493 RAEA 496 >2XKJ-E nrPDB Length = 767 Score = 691 bits (1784), Expect = 0.0, Method: Compositional matrix adjust. Identities = 334/493 (67%), Positives = 398/493 (80%) Query: 6 ERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSAR 65 E ++ EFTE AYLNY+MYVIMDRALP I DGLKPVQRRIVYAMSELGL +S K KKSAR Sbjct: 274 ENRSVAEFTEQAYLNYAMYVIMDRALPHISDGLKPVQRRIVYAMSELGLKSSGKPKKSAR 333 Query: 66 TVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRL 125 TVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPL++GQGNWG+PDDPKSFAAMRYTE++L Sbjct: 334 TVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLIEGQGNWGSPDDPKSFAAMRYTEAKL 393 Query: 126 SKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNL 185 S YSELLLSELGQGT++W NFDG+L+EP LPAR+PNILLNGTTGIAVGMATDIPPHNL Sbjct: 394 SAYSELLLSELGQGTSEWQDNFDGSLKEPITLPARVPNILLNGTTGIAVGMATDIPPHNL 453 Query: 186 REVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMRAVW 245 REV + IALI P+T+ ++L + + PD PT+AEIIT E+ KI GRGS RMRAV+ Sbjct: 454 REVVKGTIALIRNPQTSDEKLAEYIPAPDLPTKAEIITPPEELLKIQTTGRGSYRMRAVY 513 Query: 246 KKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNR 305 E +VI+ LP+QVSG++V+ QIA QM+ KKLP+V D+RDESDHENPTRLVIV RSNR Sbjct: 514 TIEKNEIVITELPYQVSGSKVITQIADQMQAKKLPLVVDVRDESDHENPTRLVIVLRSNR 573 Query: 306 VDMDQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYR 365 +D + VM+HLFATTDLE SYR+NLNMIG DGRP VK++ IL EW+ R+ TV RRL Y Sbjct: 574 IDAEAVMSHLFATTDLESSYRVNLNMIGEDGRPQVKSIRRILLEWIEIRKKTVTRRLQYH 633 Query: 366 LEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPKPALMSRFGLTETQAEAILELKLRHL 425 L ++ KRLHIL GLL+A+L+ID VI IIR ED+PKP LM F + E QAEAILELKLRHL Sbjct: 634 LNRIEKRLHILAGLLIAYLDIDTVIRIIREEDQPKPVLMEHFNIDEIQAEAILELKLRHL 693 Query: 426 AKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPLQEREE 485 AKLEEM+IR EQ EL + ++ L + + NL+ EL+ DA+ +GD+RRSP+ R E Sbjct: 694 AKLEEMEIRHEQDELSAKAAIIREQLENPESLKNLIISELKEDAKKFGDERRSPIVARAE 753 Query: 486 AKAMSEHDMLPSE 498 A + E D++P+E Sbjct: 754 AVQIKEQDLMPAE 766 >1ZVT-A nrPDB Length = 256 Score = 524 bits (1349), Expect = e-149, Method: Compositional matrix adjust. Identities = 256/256 (100%), Positives = 256/256 (100%) Query: 497 SEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAID 556 SEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAID Sbjct: 1 SEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAID 60 Query: 557 PITLPSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNR 616 PITLPSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNR Sbjct: 61 PITLPSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNR 120 Query: 617 AGKALITLPENAHVMPPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPS 676 AGKALITLPENAHVMPPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPS Sbjct: 121 AGKALITLPENAHVMPPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPS 180 Query: 677 AEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGERGRRGTLMRGLQRIDR 736 AEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGERGRRGTLMRGLQRIDR Sbjct: 181 AEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGERGRRGTLMRGLQRIDR 240 Query: 737 VEIDSPRRASSGDSEE 752 VEIDSPRRASSGDSEE Sbjct: 241 VEIDSPRRASSGDSEE 256 >6QTP-A nrPDB Length = 490 Score = 418 bits (1075), Expect = e-117, Method: Compositional matrix adjust. Identities = 228/489 (46%), Positives = 325/489 (66%), Gaps = 15/489 (3%) Query: 2 SDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFK 61 S + ER E E ++L+Y+M VI+ RALP + DGLKPV RRI+Y ++E G+ +K Sbjct: 6 SRINERNITSEMRE-SFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYK 64 Query: 62 KSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYT 121 KSAR VGDV+GKYHPHGDS+ YEAMV MAQ FSYRYPLVDGQGN+G+ D + AAMRYT Sbjct: 65 KSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGA-AAMRYT 123 Query: 122 ESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIP 181 E+R++K + LL ++ + T D++ N+DG +EP +LPAR PN+L NG +GIAVGMAT+IP Sbjct: 124 EARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIP 183 Query: 182 PHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRM 241 PHNL E+ ++L P ++ +L++ ++GPD+PT A +I ++ IR+ YE GRGS++M Sbjct: 184 PHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPT-AGLILGKSGIRRAYETGRGSIQM 242 Query: 242 --RAVWKKEDGA---VVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTR 296 RAV ++ G +V++ +P QV+ AR++E+IA +R+KK+ + DLRDE+ R Sbjct: 243 RSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVR 302 Query: 297 LVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGL-DGRPAVKNLLEILSEWLVFRR 355 +VI R + + ++N+L+ T L+ S+ +NMI L +GRP + NL E L +L ++ Sbjct: 303 VVIDVRKD-ANASVILNNLYKQTPLQTSF--GVNMIALVNGRPKLINLKEALVHYLEHQK 359 Query: 356 DTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPKPALMS---RFGLTET 412 VRRR Y L K R HILEGL +A +IDE+I IR D K A+ S RF L+E Sbjct: 360 TVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEK 419 Query: 413 QAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAY 472 QA+AIL+++LR L LE KI E +EL +L+ ILA E + L++ EL + Sbjct: 420 QAQAILDMRLRRLTGLERDKIEAEYNELLNYISELETILADEEVLLQLVRDELTEIRDRF 479 Query: 473 GDDRRSPLQ 481 GDDRR+ +Q Sbjct: 480 GDDRRTEIQ 488 >2XCO-A nrPDB Length = 726 Score = 417 bits (1072), Expect = e-116, Method: Compositional matrix adjust. Identities = 228/489 (46%), Positives = 325/489 (66%), Gaps = 15/489 (3%) Query: 2 SDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFK 61 S + ER E E ++L+Y+M VI+ RALP + DGLKPV RRI+Y ++E G+ +K Sbjct: 242 SRINERNITSEMRE-SFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYK 300 Query: 62 KSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYT 121 KSAR VGDV+GKYHPHGDS+ YEAMV MAQ FSYRYPLVDGQGN+G+ D + AAMRYT Sbjct: 301 KSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGA-AAMRYT 359 Query: 122 ESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIP 181 E+R++K + LL ++ + T D++ N+DG +EP +LPAR PN+L NG +GIAVGMAT+IP Sbjct: 360 EARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIP 419 Query: 182 PHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRM 241 PHNL E+ ++L P ++ +L++ ++GPD+PT A +I ++ IR+ YE GRGS++M Sbjct: 420 PHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPT-AGLILGKSGIRRAYETGRGSIQM 478 Query: 242 --RAVWKKEDGA---VVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTR 296 RAV ++ G +V++ +P QV+ AR++E+IA +R+KK+ + DLRDE+ R Sbjct: 479 RSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVR 538 Query: 297 LVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGL-DGRPAVKNLLEILSEWLVFRR 355 +VI R + + ++N+L+ T L+ S+ +NMI L +GRP + NL E L +L ++ Sbjct: 539 VVIDVRKD-ANASVILNNLYKQTPLQTSF--GVNMIALVNGRPKLINLKEALVHYLEHQK 595 Query: 356 DTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPKPALMS---RFGLTET 412 VRRR Y L K R HILEGL +A +IDE+I IR D K A+ S RF L+E Sbjct: 596 TVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEK 655 Query: 413 QAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAY 472 QA+AIL+++LR L LE KI E +EL +L+ ILA E + L++ EL + Sbjct: 656 QAQAILDMRLRRLTGLERDKIEAEYNELLNYISELETILADEEVLLQLVRDELTEIRDRF 715 Query: 473 GDDRRSPLQ 481 GDDRR+ +Q Sbjct: 716 GDDRRTEIQ 724 >5BS3-B nrPDB Length = 692 Score = 416 bits (1070), Expect = e-116, Method: Compositional matrix adjust. Identities = 227/489 (46%), Positives = 325/489 (66%), Gaps = 15/489 (3%) Query: 2 SDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFK 61 S + ER E E ++L+Y+M VI+ RALP + DGLKPV RRI+Y ++E G+ +K Sbjct: 208 SRINERNITSEMRE-SFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYK 266 Query: 62 KSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYT 121 KSAR VGDV+GKYHPHGDS+ YEAMV MAQ FSYRYPLVDGQGN+G+ D + AAMR+T Sbjct: 267 KSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGA-AAMRFT 325 Query: 122 ESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIP 181 E+R++K + LL ++ + T D++ N+DG +EP +LPAR PN+L NG +GIAVGMAT+IP Sbjct: 326 EARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIP 385 Query: 182 PHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRM 241 PHNL E+ ++L P ++ +L++ ++GPD+PT A +I ++ IR+ YE GRGS++M Sbjct: 386 PHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPT-AGLILGKSGIRRAYETGRGSIQM 444 Query: 242 --RAVWKKEDGA---VVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTR 296 RAV ++ G +V++ +P QV+ AR++E+IA +R+KK+ + DLRDE+ R Sbjct: 445 RSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVR 504 Query: 297 LVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGL-DGRPAVKNLLEILSEWLVFRR 355 +VI R + + ++N+L+ T L+ S+ +NMI L +GRP + NL E L +L ++ Sbjct: 505 VVIDVRKD-ANASVILNNLYKQTPLQTSF--GVNMIALVNGRPKLINLKEALVHYLEHQK 561 Query: 356 DTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPKPALMS---RFGLTET 412 VRRR Y L K R HILEGL +A +IDE+I IR D K A+ S RF L+E Sbjct: 562 TVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEK 621 Query: 413 QAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAY 472 QA+AIL+++LR L LE KI E +EL +L+ ILA E + L++ EL + Sbjct: 622 QAQAILDMRLRRLTGLERDKIEAEYNELLNYISELETILADEEVLLQLVRDELTEIRDRF 681 Query: 473 GDDRRSPLQ 481 GDDRR+ +Q Sbjct: 682 GDDRRTEIQ 690 >4DDQ-A nrPDB Length = 502 Score = 403 bits (1035), Expect = e-112, Method: Compositional matrix adjust. Identities = 213/473 (45%), Positives = 322/473 (68%), Gaps = 13/473 (2%) Query: 16 NAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYH 75 ++L+Y+M VI+ RALP + DGLKPV RRI+YAM++LG+ + +KKSAR VG+V+GKYH Sbjct: 20 TSFLDYAMSVIVSRALPDVRDGLKPVHRRILYAMNDLGMTSDKPYKKSARIVGEVIGKYH 79 Query: 76 PHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSE 135 PHGDSA YE+MV MAQ F+YRY LVDG GN+G+ D S AAMRYTE+R+SK S +L + Sbjct: 80 PHGDSAVYESMVRMAQDFNYRYMLVDGHGNFGSVDG-DSAAAMRYTEARMSKISMEILRD 138 Query: 136 LGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNLREVAQAAIAL 195 + + T D+ N+DG+ +EP ++P+R PN+L+NG GIAVGMAT+IPPH L E+ +A+ Sbjct: 139 ITKDTIDYQDNYDGSEREPVVMPSRFPNLLVNGAAGIAVGMATNIPPHQLGEIIDGVLAV 198 Query: 196 IDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMRAVWKKEDGA---- 251 + P T+ +L++++ GPD+PT +I+ R+ IRK YE+GRGS+ +RA + E + Sbjct: 199 SENPDITIPELMEVIPGPDFPTAGQIL-GRSGIRKAYESGRGSITIRAKAEIEQTSSGKE 257 Query: 252 -VVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQ 310 ++++ LP+QV+ A+++E+IA +R+KK+ + DLRDESD R+VI R + + + Sbjct: 258 RIIVTELPYQVNKAKLIEKIADLVRDKKIEGITDLRDESDR-TGMRIVIEIRRD-ANANV 315 Query: 311 VMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVL 370 ++N+L+ T L+ S+ INL + +DG+P V L + L +L ++ +RRR Y L K Sbjct: 316 ILNNLYKQTALQTSFGINL-LALVDGQPKVLTLKQCLEHYLDHQKVVIRRRTAYELRKAE 374 Query: 371 KRLHILEGLLVAFLNIDEVIEIIRNEDEPKPA---LMSRFGLTETQAEAILELKLRHLAK 427 R HILEGL VA ++D VI +IRN + A L+ +F LTE QA+AIL+++L+ L Sbjct: 375 ARAHILEGLRVALDHLDAVISLIRNSQTAEIARTGLIEQFSLTEKQAQAILDMRLQRLTG 434 Query: 428 LEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL 480 LE KI E L K +L+ ILA+E K+ ++++EL + + D+RR+ + Sbjct: 435 LEREKIEEEYQSLVKLIAELKDILANEYKVLEIIREELTEIKERFNDERRTEI 487 >3NUH-A nrPDB Length = 525 Score = 376 bits (965), Expect = e-104, Method: Compositional matrix adjust. Identities = 221/527 (41%), Positives = 329/527 (62%), Gaps = 53/527 (10%) Query: 1 MSDMAERLA---LHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNAS 57 MSD+A + + E +++YL+Y+M VI+ RALP + DGLKPV RR++YAM+ LG + + Sbjct: 1 MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWN 60 Query: 58 AKFKKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAA 117 +KKSAR VGDV+GKYHPHGDSA Y+ +V MAQPFS RY LVDGQGN+G+ D S AA Sbjct: 61 KAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDG-DSAAA 119 Query: 118 MRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMA 177 MRYTE RL+K + L+++L + T D+V N+DGT + P ++P ++PN+L+NG++GIAVGMA Sbjct: 120 MRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMA 179 Query: 178 TDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRG 237 T+IPPHNL EV +A ID +++ L++ + GPD+PT A II R I + Y GRG Sbjct: 180 TNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPT-AAIINGRRGIEEAYRTGRG 238 Query: 238 SVRMRAVWKKEDGA------VVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDH 291 V +RA + E A +++ +P+QV+ AR++E+IA ++ K++ + LRDESD Sbjct: 239 KVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDK 298 Query: 292 ENPTRLVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGL-DGRPAVKNLLEILSEW 350 + R+VI + + V + V+N+L++ T L+ S+ I NM+ L G+P + NL +I++ + Sbjct: 299 DG-MRIVIEVKRDAVG-EVVLNNLYSQTQLQVSFGI--NMVALHHGQPKIMNLKDIIAAF 354 Query: 351 LVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEP---KPALMS-- 405 + RR+ V RR + L K R HILE L VA NID +IE+IR+ P K AL++ Sbjct: 355 VRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANP 414 Query: 406 -------------------------RFG-------LTETQAEAILELKLRHLAKLEEMKI 433 FG LTE QA+AIL+L+L+ L LE K+ Sbjct: 415 WQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKL 474 Query: 434 RGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL 480 E EL + +L IL S ++ ++++EL+ + +GD RR+ + Sbjct: 475 LDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEI 521 >6N1Q-A nrPDB Length = 511 Score = 369 bits (947), Expect = e-102, Method: Compositional matrix adjust. Identities = 200/472 (42%), Positives = 302/472 (63%), Gaps = 13/472 (2%) Query: 17 AYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHP 76 ++++Y+M VI+ RALP + DGLKPV RRI+Y M+ELG+ KKSAR GDV+GKYHP Sbjct: 42 SFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKPHKKSARITGDVMGKYHP 101 Query: 77 HGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSEL 136 HGDS+ YEAMV MAQ +SYRY LVDG GN+G+ D S AA RYTE+R+SK + +L ++ Sbjct: 102 HGDSSIYEAMVRMAQWWSYRYMLVDGHGNFGSMDG-DSAAAQRYTEARMSKIALEMLRDI 160 Query: 137 GQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALI 196 + T D+V N+D +EP +LPAR PN+L+NG TGIAVGMAT+IPPHNL E A ++ Sbjct: 161 NKNTVDFVDNYDANEREPLVLPARFPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVM 220 Query: 197 DQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMRAVWKKEDGA----- 251 D P+ T L++++ GPD+PT A ++ ++ I K YE G+GS+ +R+ + E Sbjct: 221 DNPEVTTKDLMEVLPGPDFPTGA-LVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRER 279 Query: 252 VVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQV 311 +V++ P+ V+ +V E I ++ K++ + +RDES+ E ++ V R ++ + Sbjct: 280 IVVTEFPYMVNKTKVHEHIVRLVQEKRIEGITAVRDESNREGVRFVIEVKRDASANV--I 337 Query: 312 MNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLK 371 +N+LF T ++ ++ N+ I +G P + +L +IL ++ +++ V RR + EK Sbjct: 338 LNNLFKMTQMQTNFGFNMLAIQ-NGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEA 396 Query: 372 RLHILEGLLVAFLNIDEVIEIIR---NEDEPKPALMSRFGLTETQAEAILELKLRHLAKL 428 R HILEGLL+A +IDEVI IIR + E + LMS+F L+E Q++AIL+++LR L L Sbjct: 397 RAHILEGLLIALDHIDEVIRIIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGL 456 Query: 429 EEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL 480 E KI+ E +L L ILA +++ ++K EL + + D RR+ L Sbjct: 457 ERDKIQSEYDDLLALIADLADILAKPERVSQIIKDELDEVKRKFSDKRRTEL 508 >3LPX-A nrPDB Length = 500 Score = 363 bits (933), Expect = e-100, Method: Compositional matrix adjust. Identities = 209/498 (41%), Positives = 312/498 (62%), Gaps = 54/498 (10%) Query: 29 RALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAMVL 88 RALP + DGLKPV RR+++AM LG + + +KKSAR VGDV+GKYHPHGD+A Y+ +V Sbjct: 2 RALPDVRDGLKPVHRRVLFAMDVLGNDWNKAYKKSARVVGDVIGKYHPHGDTAVYDTIVR 61 Query: 89 MAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFD 148 MAQPFS RY LVDGQGN+G+ D S AAMRYTE R+SK + +L++L + T D+VPN+D Sbjct: 62 MAQPFSLRYMLVDGQGNFGSVDG-DSAAAMRYTEIRMSKIAHSILADLDKETVDFVPNYD 120 Query: 149 GTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLD 208 GT P ++P R+PN+L+NGT+GIAVGMAT+IPPHNL EV A +ALID + T +++L+ Sbjct: 121 GTEHIPAVMPTRVPNLLVNGTSGIAVGMATNIPPHNLTEVINACLALIDNSELTFEEILE 180 Query: 209 IVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMRA--------VWKKEDGAVVISALPHQ 260 + GPD+PT A II+ RA I + Y GRG +++RA KE +++ LP+Q Sbjct: 181 HIPGPDFPT-AGIISGRAGIEEAYRTGRGKIKIRARASIDVHETTGKE--TIIVHELPYQ 237 Query: 261 VSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD 320 V+ AR++E++A +++K+L + LRDESD ++ R+VI + V + V+N+L+ T Sbjct: 238 VNKARLIEKMAELVKDKRLEGISALRDESD-KDGMRMVIEIKRGEVG-EVVLNNLYKLTQ 295 Query: 321 LEKSYRINLNMIGL-DGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGL 379 ++ S+ LNM+ L +G+P + N+ E+L +++ RR+ V RR + L K R HILEGL Sbjct: 296 MQVSF--GLNMVALTNGQPKIFNIKEMLEAFVLHRREVVTRRTIFELRKARDRAHILEGL 353 Query: 380 LVAFLNIDEVIEIIRNED---EPKPALMSR------------------------------ 406 +A NID +IE+I+N + E + L+S+ Sbjct: 354 SIALANIDPIIEMIKNSNNRKESEEKLISQGWELGNVANMLSEAGNDAARPEWLEPEYGI 413 Query: 407 ----FGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLK 462 + LT QA+AI++L+L L+ +E KI E L +L ILA+ ++ ++ Sbjct: 414 RDGLYYLTAEQAKAIVDLQLYKLSGMEHDKILSEYKALLDLIAELMHILATPARLMEVIC 473 Query: 463 KELQADAQAYGDDRRSPL 480 +EL A +GD+RR+ + Sbjct: 474 EELVAIRDEFGDERRTEI 491 >3IFZ-A nrPDB Length = 508 Score = 357 bits (916), Expect = 1e-98, Method: Compositional matrix adjust. Identities = 200/489 (40%), Positives = 306/489 (62%), Gaps = 18/489 (3%) Query: 3 DMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKK 62 D E + + + + +Y++Y+M VI+ RALP + DGLKPV RR++YAM + G K Sbjct: 13 DRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAK 72 Query: 63 SARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAP-DDPKSFAAMRYT 121 SAR+V + +G YHPHGD++ Y+++V MAQP+S RYPLVDGQGN+G+P +DP AAMRYT Sbjct: 73 SARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPGNDPP--AAMRYT 130 Query: 122 ESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIP 181 E+RL+ + +L E+ + T D++PN+DG +QEP +LP+R PN+L NG+ GIAVGMAT+IP Sbjct: 131 EARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNIP 190 Query: 182 PHNLREVAQAAIALIDQ----PKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRG 237 PHNLRE+A A ++ + TL ++ V+GPD+PT I+ S+ Y+ GRG Sbjct: 191 PHNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIVGSQGTA-DAYKTGRG 249 Query: 238 SVRMRAVWKKEDG-----AVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHE 292 S+RMR V + E+ ++VI+ LP+QV+ + IA Q+R+ KL + ++ D+S Sbjct: 250 SIRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDR 309 Query: 293 NPTRLVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLV 352 R+VI + + V V+N+L+ T L+ S+ N+ I +DG P L +++ ++ Sbjct: 310 VGLRIVIEIKRDAV-AKVVINNLYKHTQLQTSFGANMLAI-VDGVPRTLRLDQLIRYYVD 367 Query: 353 FRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNE---DEPKPALMSRFGL 409 + D + RR YRL K +R HIL GL+ A +DEVI +IR D + L+ + Sbjct: 368 HQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAGLIELLDI 427 Query: 410 TETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADA 469 E QA+AIL+++LR LA LE +I + +++E E L+ ILA + +++ EL Sbjct: 428 DEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDELAEIV 487 Query: 470 QAYGDDRRS 478 +GDDRR+ Sbjct: 488 DRHGDDRRT 496 >4KPF-A nrPDB Length = 496 Score = 348 bits (893), Expect = 5e-96, Method: Compositional matrix adjust. Identities = 201/496 (40%), Positives = 313/496 (63%), Gaps = 18/496 (3%) Query: 1 MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKF 60 MS++ + ++L + + YS Y+I DRALP I DGLKPVQRRI+Y+M++ + Sbjct: 1 MSNI-QNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRILYSMNKDSNTFDKSY 59 Query: 61 KKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPD-DPKSFAAMR 119 +KSA++VG+++G +HPHGDS+ Y+AMV M+Q + R LV+ GN G+ D DP AAMR Sbjct: 60 RKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMHGNNGSMDGDPP--AAMR 117 Query: 120 YTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATD 179 YTE+RLS+ + LL ++ + T + NFD T +EP +LPA PN+L+NG+TGI+ G ATD Sbjct: 118 YTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFPNLLVNGSTGISAGYATD 177 Query: 180 IPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSV 239 IPPHNL EV AA+ +ID P +D+L++ + GPD+PT A II R EI+K YE G+G V Sbjct: 178 IPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGA-IIQGRDEIKKAYETGKGRV 236 Query: 240 RMRA---VWKKEDGA--VVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENP 294 +R+ + K + G +VI+ +P++++ A ++++I N K+ + ++RDESD + Sbjct: 237 VVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVRVNNKVAGIAEVRDESDRDG- 295 Query: 295 TRLVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDG-RPAVKNLLEILSEWLVF 353 R+ I + + + + V+N+LF TDL+ +Y N NM+ +D P ++ ILS ++ Sbjct: 296 LRIAIELKKD-ANTELVLNYLFKYTDLQINY--NFNMVAIDNFTPRQVGIVPILSSYIAH 352 Query: 354 RRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIR---NEDEPKPALMSRFGLT 410 RR+ + R + EK KRLHI+EGL+ +DEVI +IR N+ + K L + T Sbjct: 353 RREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALIRASENKADAKENLKVSYDFT 412 Query: 411 ETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQ 470 E QAEAI+ L+L L + + ++ E++EL ++ L I+ ER M NL+KKEL+ + Sbjct: 413 EEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLAAIIGDERTMYNLMKKELREVKK 472 Query: 471 AYGDDRRSPLQEREEA 486 + R S L++ +A Sbjct: 473 KFATPRLSSLEDTAKA 488 >2INR-A nrPDB Length = 514 Score = 347 bits (891), Expect = 8e-96, Method: Compositional matrix adjust. Identities = 197/498 (39%), Positives = 316/498 (63%), Gaps = 18/498 (3%) Query: 1 MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKF 60 +S++ + L+L + + + YS Y+I +RALP + DGLKPVQRRI+YAM G F Sbjct: 24 VSEIIQDLSLEDVLGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYAMYSSGNTHDKNF 83 Query: 61 KKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPD-DPKSFAAMR 119 +KSA+TVGDV+G+YHPHGDS+ YEAMV ++Q + R+ L++ GN G+ D DP AAMR Sbjct: 84 RKSAKTVGDVIGQYHPHGDSSVYEAMVRLSQDWKLRHVLIEMHGNNGSIDNDPP--AAMR 141 Query: 120 YTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATD 179 YTE++LS +E LL ++ + T ++PN+D T EP +LP+R PN+L+NG+TGI+ G ATD Sbjct: 142 YTEAKLSLLAEELLRDINKETVSFIPNYDDTTLEPMVLPSRFPNLLVNGSTGISAGYATD 201 Query: 180 IPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSV 239 IPPHNL EV QA + ID P T++QL+ ++GPD+PT I I+K YE+G+G + Sbjct: 202 IPPHNLAEVIQATLKYIDNPDITVNQLMKYIKGPDFPTGGI-IQGIDGIKKAYESGKGRI 260 Query: 240 RMRAVWKKED-----GAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENP 294 +R+ ++E ++I+ +P++V+ + ++++I +KK+ + ++RDE+D Sbjct: 261 IVRSKVEEETLRNGRKQLIITEIPYEVNKSSLVKRIDELRADKKVDGIVEVRDETDR-TG 319 Query: 295 TRLVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGL-DGRPAVKNLLEILSEWLVF 353 R+ I + + V+ + + N+L+ +DL+ SY N NM+ + DGRP + + +I+ +L Sbjct: 320 LRIAIELKKD-VNSESIKNYLYKNSDLQISY--NFNMVAISDGRPKLMGIRQIIDSYLNH 376 Query: 354 RRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIR---NEDEPKPALMSRFGLT 410 + + V R + L+ KR+HI+EGL+ A +D+VIE+IR N+ + K L+ + T Sbjct: 377 QIEVVANRTKFELDNAEKRMHIVEGLIKALSILDKVIELIRSSKNKRDAKENLIEVYEFT 436 Query: 411 ETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQ 470 E QAEAI+ L+L L + + + GE ELE QL+ IL + + N++K+EL + Sbjct: 437 EEQAEAIVMLQLYRLTNTDIVALEGEHKELEALIKQLRHILDNHDALLNVIKEELNEIKK 496 Query: 471 AYGDDRRSPLQ-EREEAK 487 + +R S ++ E EE K Sbjct: 497 KFKSERLSLIEAEIEEIK 514 >4Z53-A nrPDB Length = 742 Score = 347 bits (890), Expect = 1e-95, Method: Compositional matrix adjust. Identities = 201/496 (40%), Positives = 313/496 (63%), Gaps = 18/496 (3%) Query: 1 MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKF 60 MS++ + ++L + + YS Y+I DRALP I DGLKPVQRRI+Y+M++ + Sbjct: 247 MSNI-QNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRILYSMNKDSNTFDKSY 305 Query: 61 KKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPD-DPKSFAAMR 119 +KSA++VG+++G +HPHGDS+ Y+AMV M+Q + R LV+ GN G+ D DP AAMR Sbjct: 306 RKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMHGNNGSMDGDPP--AAMR 363 Query: 120 YTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATD 179 YTE+RLS+ + LL ++ + T + NFD T +EP +LPA PN+L+NG+TGI+ G ATD Sbjct: 364 YTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFPNLLVNGSTGISAGYATD 423 Query: 180 IPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSV 239 IPPHNL EV AA+ +ID P +D+L++ + GPD+PT A II R EI+K YE G+G V Sbjct: 424 IPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGA-IIQGRDEIKKAYETGKGRV 482 Query: 240 RMRA---VWKKEDGA--VVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENP 294 +R+ + K + G +VI+ +P++++ A ++++I N K+ + ++RDESD + Sbjct: 483 VVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVRVNNKVAGIAEVRDESDRDG- 541 Query: 295 TRLVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDG-RPAVKNLLEILSEWLVF 353 R+ I + + + + V+N+LF TDL+ +Y N NM+ +D P ++ ILS ++ Sbjct: 542 LRIAIELKKD-ANTELVLNYLFKYTDLQINY--NFNMVAIDNFTPRQVGIVPILSSYIAH 598 Query: 354 RRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIR---NEDEPKPALMSRFGLT 410 RR+ + R + EK KRLHI+EGL+ +DEVI +IR N+ + K L + T Sbjct: 599 RREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALIRASENKADAKENLKVSYDFT 658 Query: 411 ETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQ 470 E QAEAI+ L+L L + + ++ E++EL ++ L I+ ER M NL+KKEL+ + Sbjct: 659 EEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLAAIIGDERTMYNLMKKELREVKK 718 Query: 471 AYGDDRRSPLQEREEA 486 + R S L++ +A Sbjct: 719 KFATPRLSSLEDTAKA 734 >6CA8-A nrPDB Length = 751 Score = 76.3 bits (186), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 75/292 (25%), Positives = 132/292 (45%), Gaps = 28/292 (9%) Query: 8 LALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTV 67 L+ ++F + YS Y +R++P I DG KP QR+++Y + L K A+ V Sbjct: 250 LSYYDFVNKELIYYSRYD-TERSIPNIMDGWKPGQRKVLYGCFKRNLRNECKV---AQLV 305 Query: 68 GDVL--GKYHPHGDSACYEAMVLMAQPF--SYRYPLVDGQGNWGA-PDDPKSFAAMRYTE 122 G + YH HG+S+ + ++ MAQ F S ++ G +G+ + K +A RY Sbjct: 306 GYIAEHSAYH-HGESSLQQTIINMAQTFVGSNNINFLEPCGQFGSRKEGGKDASAARYIF 364 Query: 123 SRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPP 182 ++L+ + + +E ++ N +G EP+ +P IL+NG GI G ++ IP Sbjct: 365 TKLASSTRSIFNEYDDPILKYL-NEEGQKIEPQYYIPVIPTILVNGCEGIGTGYSSFIPN 423 Query: 183 HNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMR 242 +N +++ ID K +++ I P Y R E NG+ Sbjct: 424 YNYKDI-------IDNIKRYINKEPLIPMVPWYKD----FKGRIE-----SNGKTGYETI 467 Query: 243 AVWKKEDGAVV-ISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHEN 293 + K D + I+ LP + E + + ++K ++ D D S HE+ Sbjct: 468 GIINKIDNDTLEITELPIKKWTQDYKEFLEELLTDEKHQLILDYIDNSSHED 519 >1BJT-A nrPDB Length = 793 Score = 68.6 bits (166), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 85/361 (23%), Positives = 155/361 (42%), Gaps = 49/361 (13%) Query: 29 RALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAMVL 88 R++P + DG KP QR+++Y + L + K + A V + YH HG+ + + ++ Sbjct: 282 RSIPNVLDGFKPGQRKVLYGCFKKNLKSELKVAQLAPYVSECTA-YH-HGEQSLAQTIIG 339 Query: 89 MAQPF--SYRYPLVDGQGNWGA-PDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVP 145 +AQ F S L+ G +G K AA RY + L+K + + ++ Sbjct: 340 LAQNFVGSNNIYLLLPNGAFGTRATGGKDAAAARYIYTELNKLTRKIFHPADDPLYKYIQ 399 Query: 146 NFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQ 205 + T++ LP LP IL+NG GI G +T IPP N E+ + L++ + L+Q Sbjct: 400 EDEKTVEPEWYLPI-LPMILVNGAEGIGTGWSTYIPPFNPLEIIKNIRHLMNDEE--LEQ 456 Query: 206 LLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMRAVWKKEDGAVVISALPHQVSGAR 265 + +G E EI + G + D + I+ LP + + Sbjct: 457 MHPWFRGWTGTIE--------EIEPLRYRMYGRIEQIG-----DNVLEITELPARTWTST 503 Query: 266 VLEQIAAQM--RNKKLPMVDDLRDESDHENPTRLVI------VPRSNRVDMDQVMNHLFA 317 + E + + +K P + D+ E H++ + +I + ++ ++ + L + Sbjct: 504 IKEYLLLGLSGNDKIKPWIKDM--EEQHDDNIKFIITLSPEEMAKTRKIGFYERFK-LIS 560 Query: 318 TTDLEKSYRINLNMIGLDGRPAVK---NLLEILSEWLVF-------RRDTVRRRLNYRLE 367 L +NM+ D +K ++ EILSE+ R+D + RL + +E Sbjct: 561 PISL-------MNMVAFDPHGKIKKYNSVNEILSEFYYVRLEYYQKRKDHMSERLQWEVE 613 Query: 368 K 368 K Sbjct: 614 K 614 >5GWJ-A nrPDB Length = 803 Score = 62.4 bits (150), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 51/196 (26%), Positives = 90/196 (45%), Gaps = 10/196 (5%) Query: 9 ALHEFTENAYLNYSMYVIMD----RALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSA 64 A T N ++N + + + R++P + DG KP QR++++ + K + A Sbjct: 287 ATKHLTYNDFINKELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLA 346 Query: 65 RTVGDVLGKYHPHGDSACYEAMVLMAQPF--SYRYPLVDGQGNWGAP-DDPKSFAAMRYT 121 +V + + YH HG+ A +V +AQ F S L+ G +G K A+ RY Sbjct: 347 GSVAE-MSAYH-HGEQALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYI 404 Query: 122 ESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIP 181 + LS + LL + ++ + D EP+ +P +L+NG GI G A +P Sbjct: 405 FTMLSTLARLLFPAVDDNLLKFLYD-DNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLP 463 Query: 182 PHNLREVAQAAIALID 197 ++ RE+ ++D Sbjct: 464 NYDAREIVNNVRRMLD 479 >4ELZ-A nrPDB Length = 153 Score = 62.4 bits (150), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 54/140 (38%), Positives = 64/140 (45%), Gaps = 37/140 (26%) Query: 351 LVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEP---KPALMSR- 406 LV R + RR + L K R HILEGL +A NIDE+IE+I+N P K L+SR Sbjct: 14 LVPRGSHMTRRTIFELRKARDRAHILEGLALALANIDEIIELIKNAPTPAEAKEGLISRG 73 Query: 407 --------------------------FG-------LTETQAEAILELKLRHLAKLEEMKI 433 FG LTE QA+AILEL+L L LE KI Sbjct: 74 WDLGNVASMLERAGTDAARPDWLEPEFGIREGKYFLTEQQAQAILELRLHRLTGLEHEKI 133 Query: 434 RGEQSELEKERDQLQGILAS 453 E L E +L ILAS Sbjct: 134 LDEYKALLDEIAELMHILAS 153 >4FM9-A nrPDB Length = 763 Score = 62.0 bits (149), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 51/192 (26%), Positives = 90/192 (46%), Gaps = 10/192 (5%) Query: 13 FTENAYLNYSMYVIMD----RALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVG 68 T N ++N + + + R++P + DGLKP QR++++ + K + A +V Sbjct: 263 LTYNDFINKELILFSNSDNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVA 322 Query: 69 DVLGKYHPHGDSACYEAMVLMAQPF--SYRYPLVDGQGNWGAP-DDPKSFAAMRYTESRL 125 + + YH HG+ + ++ +AQ F S L+ G +G K A+ RY + L Sbjct: 323 E-MSSYH-HGEMSLMMTIINLAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTML 380 Query: 126 SKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNL 185 S + LL T ++ + D EP+ +P +L+NG GI G + IP ++ Sbjct: 381 SSLARLLFPPKDDHTLKFLYD-DNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDV 439 Query: 186 REVAQAAIALID 197 RE+ L+D Sbjct: 440 REIVNNIRRLMD 451 >4ELY-A nrPDB Length = 156 Score = 53.1 bits (126), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 49/140 (35%), Positives = 63/140 (45%), Gaps = 37/140 (26%) Query: 351 LVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEP---KPALMS-- 405 LV R + RR + L K R HILE L VA NID +IE+IR+ P K AL++ Sbjct: 14 LVPRGSHMTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANP 73 Query: 406 -------------------------RFG-------LTETQAEAILELKLRHLAKLEEMKI 433 FG LTE QA+AIL+L+L+ L LE K+ Sbjct: 74 WQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKL 133 Query: 434 RGEQSELEKERDQLQGILAS 453 E EL + +L IL S Sbjct: 134 LDEYKELLDQIAELLRILGS 153 >1X75-A nrPDB Length = 132 Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 46/131 (35%), Positives = 59/131 (45%), Gaps = 37/131 (28%) Query: 360 RRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEP---KPALMS----------- 405 RR + L K R HILE L VA NID +IE+IR+ P K AL++ Sbjct: 2 RRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAM 61 Query: 406 ----------------RFG-------LTETQAEAILELKLRHLAKLEEMKIRGEQSELEK 442 FG LTE QA+AIL+L+L+ L LE K+ E EL Sbjct: 62 LERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLD 121 Query: 443 ERDQLQGILAS 453 + +L IL S Sbjct: 122 QIAELLRILGS 132 >1K2W-A nrPDB Length = 256 Score = 35.4 bits (80), Expect = 0.094, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 35/72 (48%), Gaps = 3/72 (4%) Query: 631 MPPVV--IEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQ 688 + P+V ++ D L AI +G + M ++ G+G KIIN+ S RGE L Sbjct: 92 LAPIVEITRESYDRLFAINVSGTLFMMQAVARAMIAGGRGGKIINMASQAGRRGE-ALVG 150 Query: 689 LYVLPPQSTLTI 700 +Y + +++ Sbjct: 151 VYCATKAAVISL 162 >4E6P-A nrPDB Length = 259 Score = 35.0 bits (79), Expect = 0.12, Method: Compositional matrix adjust. Identities = 19/72 (26%), Positives = 36/72 (50%), Gaps = 3/72 (4%) Query: 631 MPPVV--IEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQ 688 + P+V ++ + L AI AG + + +++G+G KIIN+ S RGE L Sbjct: 95 LAPIVEITRESYEKLFAINVAGTLFTLQAAARQMIAQGRGGKIINMASQAGRRGE-ALVA 153 Query: 689 LYVLPPQSTLTI 700 +Y + +++ Sbjct: 154 IYCATKAAVISL 165 >2VDU-B nrPDB Length = 450 Score = 34.3 bits (77), Expect = 0.22, Method: Compositional matrix adjust. Identities = 16/57 (28%), Positives = 31/57 (54%), Gaps = 3/57 (5%) Query: 543 VVFVDSTGRSYAIDPITLPSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASD 599 V+ D G Y+ID ++P + EP+ G +++ T H++ +SD + ++ SD Sbjct: 164 VIIADKFGDVYSIDINSIPEEKFTQEPILGHVSM---LTDVHLIKDSDGHQFIITSD 217 >2PCN-A nrPDB Length = 161 Score = 32.3 bits (72), Expect = 0.76, Method: Composition-based stats. Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 6/87 (6%) Query: 657 VSDLPQLSKGKGNKIINIPSAEAARGEDGL---AQLYVLPPQSTLTIH-VGKRKIKLRPE 712 V +LP S G G ++ + P A ED + L +PP + L + G R++ L + Sbjct: 16 VCELPFQSYG-GKRMFSGPIATVDVFEDNVLVREALETVPPGTVLVVDGKGSRRVALLGD 74 Query: 713 ELQKVTGERGRRGTLMRGLQRIDRVEI 739 L ++ ERG G ++ G R D EI Sbjct: 75 RLAQIACERGLAGVIIHGCIR-DSAEI 100 >4TR2-A nrPDB Length = 663 Score = 29.3 bits (64), Expect = 7.0, Method: Compositional matrix adjust. Identities = 19/70 (27%), Positives = 37/70 (52%), Gaps = 12/70 (17%) Query: 438 SELEKERDQLQGILASERKM---------NNLLKKELQADAQAYGDDRRSPLQEREEAKA 488 +E +KE+D + I++ R + +N+ +++ADA AY DR +P +EE + Sbjct: 47 NEGKKEKDDVHKIISELRFLQKVETILESSNMSVSDVEADANAYNPDRDAP---KEELQK 103 Query: 489 MSEHDMLPSE 498 + + PS+ Sbjct: 104 LQDQQETPSK 113 >4G3N-A nrPDB Length = 327 Score = 29.3 bits (64), Expect = 7.3, Method: Compositional matrix adjust. Identities = 37/194 (19%), Positives = 82/194 (42%), Gaps = 18/194 (9%) Query: 499 PVTIVLSQMGWVRSAKGHDIDAP------GLNYKAGDSFKAAVKGKSNQPVVFVDSTGRS 552 P ++ ++ G V+ +K D D+ +N + D AV + ++ V + G+S Sbjct: 110 PYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQS 169 Query: 553 YAIDPITLPSARGQGEPLTGKLTLPPGATVDHMLME----SDDQKLLMASDAGYGFVCTF 608 T + R G +G + +D L+ + LL+A+ GY Sbjct: 170 IRFSA-TDEALRPMGRATSGVQGMRF--NIDDRLLSLNVVREGTYLLVATSGGYAKRTAI 226 Query: 609 NDLVARNRAGKALITL---PENAHVMPPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSK 665 + + R GK ++T+ ++ ++++D S+ L A+T G ++ + + + Sbjct: 227 EEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSE-LYAVTSGGGVIRTAARQVRKAGR 285 Query: 666 -GKGNKIINIPSAE 678 KG +++N+ + Sbjct: 286 QTKGVRLMNLGEGD 299 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1ZVU-A nrPDB 1212 0.0 5EIX-A nrPDB 727 0.0 6BQ9-A nrPDB 696 0.0 2XKJ-E nrPDB 689 0.0 2XCO-A nrPDB 644 0.0 5BS3-B nrPDB 642 0.0 4DDQ-A nrPDB 637 0.0 6QTP-A nrPDB 635 0.0 6N1Q-A nrPDB 632 0.0 3NUH-A nrPDB 625 e-179 4Z53-A nrPDB 598 e-171 3LPX-A nrPDB 596 e-170 4KPF-A nrPDB 594 e-170 3IFZ-A nrPDB 593 e-170 2INR-A nrPDB 591 e-169 1ZVT-A nrPDB 540 e-153 1BJT-A nrPDB 349 2e-96 6CA8-A nrPDB 335 4e-92 5GWJ-A nrPDB 288 7e-78 4FM9-A nrPDB 288 8e-78 4ELZ-A nrPDB 131 9e-31 4ELY-A nrPDB 130 2e-30 1X75-A nrPDB 119 4e-27 Sequences not found previously or not previously below threshold: 1K2W-A nrPDB 35 0.085 4E6P-A nrPDB 35 0.12 5AMO-A nrPDB 34 0.19 2VDU-B nrPDB 34 0.21 2PCN-A nrPDB 34 0.21 5MLZ-A nrPDB 33 0.43 5J6F-A nrPDB 33 0.46 5MRE-R nrPDB 33 0.58 5EXR-B nrPDB 32 0.80 4BPX-B nrPDB 32 0.80 4YDH-A nrPDB 32 0.81 4G3N-A nrPDB 32 0.90 4BPU-B nrPDB 32 1.1 5YZ0-C nrPDB 32 1.4 2CSB-A nrPDB 32 1.4 4GFJ-A nrPDB 31 1.9 5HM5-A nrPDB 31 2.0 3VR3-D nrPDB 31 2.1 1XI9-A nrPDB 30 2.7 2QAG-C nrPDB 30 3.3 3EUH-A nrPDB 30 4.2 2TMA-A nrPDB 30 4.3 3R3S-A nrPDB 30 4.9 2I1J-A nrPDB 30 5.0 3JVD-A nrPDB 30 5.3 5JQE-A nrPDB 29 7.7 CONVERGED! >1ZVU-A nrPDB Length = 716 Score = 1212 bits (3136), Expect = 0.0, Method: Composition-based stats. Identities = 716/716 (100%), Positives = 716/716 (100%) Query: 27 MDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAM 86 MDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAM Sbjct: 1 MDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAM 60 Query: 87 VLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPN 146 VLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPN Sbjct: 61 VLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPN 120 Query: 147 FDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQL 206 FDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQL Sbjct: 121 FDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQL 180 Query: 207 LDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMRAVWKKEDGAVVISALPHQVSGARV 266 LDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMRAVWKKEDGAVVISALPHQVSGARV Sbjct: 181 LDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMRAVWKKEDGAVVISALPHQVSGARV 240 Query: 267 LEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTDLEKSYR 326 LEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTDLEKSYR Sbjct: 241 LEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTDLEKSYR 300 Query: 327 INLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNI 386 INLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNI Sbjct: 301 INLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNI 360 Query: 387 DEVIEIIRNEDEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQ 446 DEVIEIIRNEDEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQ Sbjct: 361 DEVIEIIRNEDEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQ 420 Query: 447 LQGILASERKMNNLLKKELQADAQAYGDDRRSPLQEREEAKAMSEHDMLPSEPVTIVLSQ 506 LQGILASERKMNNLLKKELQADAQAYGDDRRSPLQEREEAKAMSEHDMLPSEPVTIVLSQ Sbjct: 421 LQGILASERKMNNLLKKELQADAQAYGDDRRSPLQEREEAKAMSEHDMLPSEPVTIVLSQ 480 Query: 507 MGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITLPSARGQ 566 MGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITLPSARGQ Sbjct: 481 MGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITLPSARGQ 540 Query: 567 GEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPE 626 GEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPE Sbjct: 541 GEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPE 600 Query: 627 NAHVMPPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGL 686 NAHVMPPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGL Sbjct: 601 NAHVMPPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGL 660 Query: 687 AQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGERGRRGTLMRGLQRIDRVEIDSP 742 AQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGERGRRGTLMRGLQRIDRVEIDSP Sbjct: 661 AQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGERGRRGTLMRGLQRIDRVEIDSP 716 >5EIX-A nrPDB Length = 741 Score = 727 bits (1876), Expect = 0.0, Method: Composition-based stats. Identities = 469/490 (95%), Positives = 482/490 (98%) Query: 1 MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKF 60 MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKF Sbjct: 246 MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKF 305 Query: 61 KKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRY 120 KKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPL DGQGNWGAPDDPKSFAAMRY Sbjct: 306 KKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLGDGQGNWGAPDDPKSFAAMRY 365 Query: 121 TESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDI 180 TESRLSKY+ELLLSELGQGT DWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDI Sbjct: 366 TESRLSKYAELLLSELGQGTVDWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDI 425 Query: 181 PPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR 240 PPHNLREVA+AAI LI+QPKTTLD+LLDIVQGPD+PTEAEIITSRAEIRKIY+NGRGSVR Sbjct: 426 PPHNLREVAKAAITLIEQPKTTLDELLDIVQGPDFPTEAEIITSRAEIRKIYQNGRGSVR 485 Query: 241 MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIV 300 MRAVW KEDGAVVI+ALPHQVSGA+VLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIV Sbjct: 486 MRAVWSKEDGAVVITALPHQVSGAKVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIV 545 Query: 301 PRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRR 360 PRSNRVDM+QVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRR Sbjct: 546 PRSNRVDMEQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRR 605 Query: 361 RLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPKPALMSRFGLTETQAEAILEL 420 RLN+RLEKVLKRLHILEGLLVAFLNIDEVIEIIR EDEPKPALMSRFG++ETQAEAILEL Sbjct: 606 RLNHRLEKVLKRLHILEGLLVAFLNIDEVIEIIRTEDEPKPALMSRFGISETQAEAILEL 665 Query: 421 KLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL 480 KLRHLAKLEEMKIRGEQSELEKERDQLQ ILASERKMNNLLKKELQADA A+GDDRRSPL Sbjct: 666 KLRHLAKLEEMKIRGEQSELEKERDQLQAILASERKMNNLLKKELQADADAFGDDRRSPL 725 Query: 481 QEREEAKAMS 490 EREEAKAMS Sbjct: 726 HEREEAKAMS 735 >6BQ9-A nrPDB Length = 496 Score = 696 bits (1796), Expect = 0.0, Method: Composition-based stats. Identities = 365/484 (75%), Positives = 424/484 (87%) Query: 3 DMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKK 62 D ER +L +FTE AYLNYSMYVIMDRALP IGDGLKPVQRRIVYAMSELGL+A AK KK Sbjct: 13 DGVERRSLADFTEQAYLNYSMYVIMDRALPHIGDGLKPVQRRIVYAMSELGLDADAKHKK 72 Query: 63 SARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTE 122 SARTVGDVLGK+HPHGDSACYEAMVLMAQPFSYRY LVDGQGNWGAPDDPKSFAAMRYTE Sbjct: 73 SARTVGDVLGKFHPHGDSACYEAMVLMAQPFSYRYTLVDGQGNWGAPDDPKSFAAMRYTE 132 Query: 123 SRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPP 182 +RLS+Y+E+LLSE+GQGT DWVPNFDGTLQEP +LPARLPNILLNGTTGIAVGMATD+PP Sbjct: 133 ARLSRYAEVLLSEVGQGTVDWVPNFDGTLQEPAVLPARLPNILLNGTTGIAVGMATDVPP 192 Query: 183 HNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMR 242 HNLREVA A + L+D+PK T++QL + +QGPDYPTEAEI+T RAEI K+YE+GRGS+RMR Sbjct: 193 HNLREVASACVRLLDEPKATIEQLCEHIQGPDYPTEAEIVTPRAEILKMYESGRGSIRMR 252 Query: 243 AVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPR 302 AV++ EDG +V++ALPHQVSGA+VLEQIAAQM+ KKLPMV DLRDESDHENP R+VI+PR Sbjct: 253 AVYRVEDGDIVVTALPHQVSGAKVLEQIAAQMQAKKLPMVADLRDESDHENPCRIVIIPR 312 Query: 303 SNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRL 362 SNRVD+D++M HLFATTDLE +YR+N+N+IGLDGRP +KNL +L EWL FR +TVRRRL Sbjct: 313 SNRVDVDELMQHLFATTDLESTYRVNVNIIGLDGRPQLKNLRTLLVEWLEFRTNTVRRRL 372 Query: 363 NYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPKPALMSRFGLTETQAEAILELKL 422 +RL+KV KRLH+L+GLL AFLN+DEVI IIR E+ PK AL+ RF LTE QA+ ILE +L Sbjct: 373 QHRLDKVEKRLHLLDGLLTAFLNLDEVIHIIRTEEYPKQALIERFELTEIQADYILETRL 432 Query: 423 RHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPLQE 482 R LA+LEEMKIRGEQ EL KE+ +LQ +L SE K+ L++ EL DA+ YGDDRRSP+ Sbjct: 433 RQLARLEEMKIRGEQDELLKEQAKLQALLGSEAKLRKLVRSELIKDAETYGDDRRSPIVA 492 Query: 483 REEA 486 R EA Sbjct: 493 RAEA 496 >2XKJ-E nrPDB Length = 767 Score = 689 bits (1778), Expect = 0.0, Method: Composition-based stats. Identities = 334/493 (67%), Positives = 398/493 (80%) Query: 6 ERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSAR 65 E ++ EFTE AYLNY+MYVIMDRALP I DGLKPVQRRIVYAMSELGL +S K KKSAR Sbjct: 274 ENRSVAEFTEQAYLNYAMYVIMDRALPHISDGLKPVQRRIVYAMSELGLKSSGKPKKSAR 333 Query: 66 TVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRL 125 TVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPL++GQGNWG+PDDPKSFAAMRYTE++L Sbjct: 334 TVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLIEGQGNWGSPDDPKSFAAMRYTEAKL 393 Query: 126 SKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNL 185 S YSELLLSELGQGT++W NFDG+L+EP LPAR+PNILLNGTTGIAVGMATDIPPHNL Sbjct: 394 SAYSELLLSELGQGTSEWQDNFDGSLKEPITLPARVPNILLNGTTGIAVGMATDIPPHNL 453 Query: 186 REVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMRAVW 245 REV + IALI P+T+ ++L + + PD PT+AEIIT E+ KI GRGS RMRAV+ Sbjct: 454 REVVKGTIALIRNPQTSDEKLAEYIPAPDLPTKAEIITPPEELLKIQTTGRGSYRMRAVY 513 Query: 246 KKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNR 305 E +VI+ LP+QVSG++V+ QIA QM+ KKLP+V D+RDESDHENPTRLVIV RSNR Sbjct: 514 TIEKNEIVITELPYQVSGSKVITQIADQMQAKKLPLVVDVRDESDHENPTRLVIVLRSNR 573 Query: 306 VDMDQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYR 365 +D + VM+HLFATTDLE SYR+NLNMIG DGRP VK++ IL EW+ R+ TV RRL Y Sbjct: 574 IDAEAVMSHLFATTDLESSYRVNLNMIGEDGRPQVKSIRRILLEWIEIRKKTVTRRLQYH 633 Query: 366 LEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPKPALMSRFGLTETQAEAILELKLRHL 425 L ++ KRLHIL GLL+A+L+ID VI IIR ED+PKP LM F + E QAEAILELKLRHL Sbjct: 634 LNRIEKRLHILAGLLIAYLDIDTVIRIIREEDQPKPVLMEHFNIDEIQAEAILELKLRHL 693 Query: 426 AKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPLQEREE 485 AKLEEM+IR EQ EL + ++ L + + NL+ EL+ DA+ +GD+RRSP+ R E Sbjct: 694 AKLEEMEIRHEQDELSAKAAIIREQLENPESLKNLIISELKEDAKKFGDERRSPIVARAE 753 Query: 486 AKAMSEHDMLPSE 498 A + E D++P+E Sbjct: 754 AVQIKEQDLMPAE 766 >2XCO-A nrPDB Length = 726 Score = 644 bits (1661), Expect = 0.0, Method: Composition-based stats. Identities = 223/488 (45%), Positives = 322/488 (65%), Gaps = 13/488 (2%) Query: 2 SDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFK 61 S + ER E E ++L+Y+M VI+ RALP + DGLKPV RRI+Y ++E G+ +K Sbjct: 242 SRINERNITSEMRE-SFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYK 300 Query: 62 KSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYT 121 KSAR VGDV+GKYHPHGDS+ YEAMV MAQ FSYRYPLVDGQGN+G+ D AAMRYT Sbjct: 301 KSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDG-DGAAAMRYT 359 Query: 122 ESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIP 181 E+R++K + LL ++ + T D++ N+DG +EP +LPAR PN+L NG +GIAVGMAT+IP Sbjct: 360 EARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIP 419 Query: 182 PHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRM 241 PHNL E+ ++L P ++ +L++ ++GPD+PT A +I ++ IR+ YE GRGS++M Sbjct: 420 PHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPT-AGLILGKSGIRRAYETGRGSIQM 478 Query: 242 RAVWKKEDGA-----VVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTR 296 R+ E+ +V++ +P QV+ AR++E+IA +R+KK+ + DLRDE+ R Sbjct: 479 RSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVR 538 Query: 297 LVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRD 356 +VI R + + ++N+L+ T L+ S+ +N+ + ++GRP + NL E L +L ++ Sbjct: 539 VVIDVRKD-ANASVILNNLYKQTPLQTSFGVNM-IALVNGRPKLINLKEALVHYLEHQKT 596 Query: 357 TVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPKPALMS---RFGLTETQ 413 VRRR Y L K R HILEGL +A +IDE+I IR D K A+ S RF L+E Q Sbjct: 597 VVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEKQ 656 Query: 414 AEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYG 473 A+AIL+++LR L LE KI E +EL +L+ ILA E + L++ EL +G Sbjct: 657 AQAILDMRLRRLTGLERDKIEAEYNELLNYISELETILADEEVLLQLVRDELTEIRDRFG 716 Query: 474 DDRRSPLQ 481 DDRR+ +Q Sbjct: 717 DDRRTEIQ 724 >5BS3-B nrPDB Length = 692 Score = 642 bits (1655), Expect = 0.0, Method: Composition-based stats. Identities = 222/488 (45%), Positives = 322/488 (65%), Gaps = 13/488 (2%) Query: 2 SDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFK 61 S + ER E E ++L+Y+M VI+ RALP + DGLKPV RRI+Y ++E G+ +K Sbjct: 208 SRINERNITSEMRE-SFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYK 266 Query: 62 KSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYT 121 KSAR VGDV+GKYHPHGDS+ YEAMV MAQ FSYRYPLVDGQGN+G+ D AAMR+T Sbjct: 267 KSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDG-DGAAAMRFT 325 Query: 122 ESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIP 181 E+R++K + LL ++ + T D++ N+DG +EP +LPAR PN+L NG +GIAVGMAT+IP Sbjct: 326 EARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIP 385 Query: 182 PHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRM 241 PHNL E+ ++L P ++ +L++ ++GPD+PT A +I ++ IR+ YE GRGS++M Sbjct: 386 PHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPT-AGLILGKSGIRRAYETGRGSIQM 444 Query: 242 RAVWKKEDGA-----VVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTR 296 R+ E+ +V++ +P QV+ AR++E+IA +R+KK+ + DLRDE+ R Sbjct: 445 RSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVR 504 Query: 297 LVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRD 356 +VI R + + ++N+L+ T L+ S+ +N+ + ++GRP + NL E L +L ++ Sbjct: 505 VVIDVRKD-ANASVILNNLYKQTPLQTSFGVNM-IALVNGRPKLINLKEALVHYLEHQKT 562 Query: 357 TVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPKPALMS---RFGLTETQ 413 VRRR Y L K R HILEGL +A +IDE+I IR D K A+ S RF L+E Q Sbjct: 563 VVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEKQ 622 Query: 414 AEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYG 473 A+AIL+++LR L LE KI E +EL +L+ ILA E + L++ EL +G Sbjct: 623 AQAILDMRLRRLTGLERDKIEAEYNELLNYISELETILADEEVLLQLVRDELTEIRDRFG 682 Query: 474 DDRRSPLQ 481 DDRR+ +Q Sbjct: 683 DDRRTEIQ 690 >4DDQ-A nrPDB Length = 502 Score = 637 bits (1642), Expect = 0.0, Method: Composition-based stats. Identities = 213/499 (42%), Positives = 330/499 (66%), Gaps = 14/499 (2%) Query: 5 AERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSA 64 + + + ++L+Y+M VI+ RALP + DGLKPV RRI+YAM++LG+ + +KKSA Sbjct: 9 VREINISQEMRTSFLDYAMSVIVSRALPDVRDGLKPVHRRILYAMNDLGMTSDKPYKKSA 68 Query: 65 RTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESR 124 R VG+V+GKYHPHGDSA YE+MV MAQ F+YRY LVDG GN+G+ D S AAMRYTE+R Sbjct: 69 RIVGEVIGKYHPHGDSAVYESMVRMAQDFNYRYMLVDGHGNFGSVDG-DSAAAMRYTEAR 127 Query: 125 LSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHN 184 +SK S +L ++ + T D+ N+DG+ +EP ++P+R PN+L+NG GIAVGMAT+IPPH Sbjct: 128 MSKISMEILRDITKDTIDYQDNYDGSEREPVVMPSRFPNLLVNGAAGIAVGMATNIPPHQ 187 Query: 185 LREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMRAV 244 L E+ +A+ + P T+ +L++++ GPD+PT +I+ R+ IRK YE+GRGS+ +RA Sbjct: 188 LGEIIDGVLAVSENPDITIPELMEVIPGPDFPTAGQIL-GRSGIRKAYESGRGSITIRAK 246 Query: 245 WKKEDGA-----VVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVI 299 + E + ++++ LP+QV+ A+++E+IA +R+KK+ + DLRDESD R+VI Sbjct: 247 AEIEQTSSGKERIIVTELPYQVNKAKLIEKIADLVRDKKIEGITDLRDESDR-TGMRIVI 305 Query: 300 VPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVR 359 R + + + ++N+L+ T L+ S+ INL + +DG+P V L + L +L ++ +R Sbjct: 306 EIRRD-ANANVILNNLYKQTALQTSFGINLLAL-VDGQPKVLTLKQCLEHYLDHQKVVIR 363 Query: 360 RRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDE---PKPALMSRFGLTETQAEA 416 RR Y L K R HILEGL VA ++D VI +IRN + L+ +F LTE QA+A Sbjct: 364 RRTAYELRKAEARAHILEGLRVALDHLDAVISLIRNSQTAEIARTGLIEQFSLTEKQAQA 423 Query: 417 ILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDR 476 IL+++L+ L LE KI E L K +L+ ILA+E K+ ++++EL + + D+R Sbjct: 424 ILDMRLQRLTGLEREKIEEEYQSLVKLIAELKDILANEYKVLEIIREELTEIKERFNDER 483 Query: 477 RSPLQEREEAKAMSEHDML 495 R+ + + + + D++ Sbjct: 484 RTEIV-TSGLETIEDEDLI 501 >6QTP-A nrPDB Length = 490 Score = 635 bits (1637), Expect = 0.0, Method: Composition-based stats. Identities = 223/488 (45%), Positives = 322/488 (65%), Gaps = 13/488 (2%) Query: 2 SDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFK 61 S + ER E E ++L+Y+M VI+ RALP + DGLKPV RRI+Y ++E G+ +K Sbjct: 6 SRINERNITSEMRE-SFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYK 64 Query: 62 KSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYT 121 KSAR VGDV+GKYHPHGDS+ YEAMV MAQ FSYRYPLVDGQGN+G+ D AAMRYT Sbjct: 65 KSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDG-DGAAAMRYT 123 Query: 122 ESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIP 181 E+R++K + LL ++ + T D++ N+DG +EP +LPAR PN+L NG +GIAVGMAT+IP Sbjct: 124 EARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIP 183 Query: 182 PHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRM 241 PHNL E+ ++L P ++ +L++ ++GPD+PT A +I ++ IR+ YE GRGS++M Sbjct: 184 PHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPT-AGLILGKSGIRRAYETGRGSIQM 242 Query: 242 RAVWKKEDGA-----VVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTR 296 R+ E+ +V++ +P QV+ AR++E+IA +R+KK+ + DLRDE+ R Sbjct: 243 RSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVR 302 Query: 297 LVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRD 356 +VI R + + ++N+L+ T L+ S+ +N+ + ++GRP + NL E L +L ++ Sbjct: 303 VVIDVRKD-ANASVILNNLYKQTPLQTSFGVNM-IALVNGRPKLINLKEALVHYLEHQKT 360 Query: 357 TVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPKPALMS---RFGLTETQ 413 VRRR Y L K R HILEGL +A +IDE+I IR D K A+ S RF L+E Q Sbjct: 361 VVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEKQ 420 Query: 414 AEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYG 473 A+AIL+++LR L LE KI E +EL +L+ ILA E + L++ EL +G Sbjct: 421 AQAILDMRLRRLTGLERDKIEAEYNELLNYISELETILADEEVLLQLVRDELTEIRDRFG 480 Query: 474 DDRRSPLQ 481 DDRR+ +Q Sbjct: 481 DDRRTEIQ 488 >6N1Q-A nrPDB Length = 511 Score = 632 bits (1630), Expect = 0.0, Method: Composition-based stats. Identities = 202/482 (41%), Positives = 306/482 (63%), Gaps = 13/482 (2%) Query: 7 RLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSART 66 + L + + ++++Y+M VI+ RALP + DGLKPV RRI+Y M+ELG+ KKSAR Sbjct: 32 NVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKPHKKSARI 91 Query: 67 VGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLS 126 GDV+GKYHPHGDS+ YEAMV MAQ +SYRY LVDG GN+G+ D S AA RYTE+R+S Sbjct: 92 TGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVDGHGNFGSMDG-DSAAAQRYTEARMS 150 Query: 127 KYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNLR 186 K + +L ++ + T D+V N+D +EP +LPAR PN+L+NG TGIAVGMAT+IPPHNL Sbjct: 151 KIALEMLRDINKNTVDFVDNYDANEREPLVLPARFPNLLVNGATGIAVGMATNIPPHNLG 210 Query: 187 EVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMRAVWK 246 E A ++D P+ T L++++ GPD+PT A ++ ++ I K YE G+GS+ +R+ + Sbjct: 211 ETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTGA-LVMGKSGIHKAYETGKGSIVLRSRTE 269 Query: 247 KEDGA-----VVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVP 301 E +V++ P+ V+ +V E I ++ K++ + +RDES+ E R VI Sbjct: 270 IETTKTGRERIVVTEFPYMVNKTKVHEHIVRLVQEKRIEGITAVRDESNRE-GVRFVIEV 328 Query: 302 RSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRR 361 + + + ++N+LF T ++ ++ N+ I +G P + +L +IL ++ +++ V RR Sbjct: 329 KRD-ASANVILNNLFKMTQMQTNFGFNMLAIQ-NGIPKILSLRQILDAYIEHQKEVVVRR 386 Query: 362 LNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIR---NEDEPKPALMSRFGLTETQAEAIL 418 + EK R HILEGLL+A +IDEVI IIR + E + LMS+F L+E Q++AIL Sbjct: 387 TRFDKEKAEARAHILEGLLIALDHIDEVIRIIRASETDAEAQAELMSKFKLSERQSQAIL 446 Query: 419 ELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRS 478 +++LR L LE KI+ E +L L ILA +++ ++K EL + + D RR+ Sbjct: 447 DMRLRRLTGLERDKIQSEYDDLLALIADLADILAKPERVSQIIKDELDEVKRKFSDKRRT 506 Query: 479 PL 480 L Sbjct: 507 EL 508 >3NUH-A nrPDB Length = 525 Score = 625 bits (1611), Expect = e-179, Method: Composition-based stats. Identities = 219/529 (41%), Positives = 329/529 (62%), Gaps = 53/529 (10%) Query: 1 MSDMAERLA---LHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNAS 57 MSD+A + + E +++YL+Y+M VI+ RALP + DGLKPV RR++YAM+ LG + + Sbjct: 1 MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWN 60 Query: 58 AKFKKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAA 117 +KKSAR VGDV+GKYHPHGDSA Y+ +V MAQPFS RY LVDGQGN+G+ D S AA Sbjct: 61 KAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDG-DSAAA 119 Query: 118 MRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMA 177 MRYTE RL+K + L+++L + T D+V N+DGT + P ++P ++PN+L+NG++GIAVGMA Sbjct: 120 MRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMA 179 Query: 178 TDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRG 237 T+IPPHNL EV +A ID +++ L++ + GPD+PT A II R I + Y GRG Sbjct: 180 TNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAA-IINGRRGIEEAYRTGRG 238 Query: 238 SVRMRAVWKKEDGA------VVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDH 291 V +RA + E A +++ +P+QV+ AR++E+IA ++ K++ + LRDESD Sbjct: 239 KVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESD- 297 Query: 292 ENPTRLVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGL-DGRPAVKNLLEILSEW 350 ++ R+VI + + V + V+N+L++ T L+ S+ I NM+ L G+P + NL +I++ + Sbjct: 298 KDGMRIVIEVKRDAVG-EVVLNNLYSQTQLQVSFGI--NMVALHHGQPKIMNLKDIIAAF 354 Query: 351 LVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEP---KPALMS-- 405 + RR+ V RR + L K R HILE L VA NID +IE+IR+ P K AL++ Sbjct: 355 VRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANP 414 Query: 406 --------------------------------RFGLTETQAEAILELKLRHLAKLEEMKI 433 + LTE QA+AIL+L+L+ L LE K+ Sbjct: 415 WQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKL 474 Query: 434 RGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPLQE 482 E EL + +L IL S ++ ++++EL+ + +GD RR+ + Sbjct: 475 LDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITA 523 >4Z53-A nrPDB Length = 742 Score = 598 bits (1542), Expect = e-171, Method: Composition-based stats. Identities = 198/495 (40%), Positives = 309/495 (62%), Gaps = 16/495 (3%) Query: 1 MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKF 60 MS++ + ++L + + YS Y+I DRALP I DGLKPVQRRI+Y+M++ + Sbjct: 247 MSNI-QNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRILYSMNKDSNTFDKSY 305 Query: 61 KKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRY 120 +KSA++VG+++G +HPHGDS+ Y+AMV M+Q + R LV+ GN G+ D AAMRY Sbjct: 306 RKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMHGNNGSMDGDP-PAAMRY 364 Query: 121 TESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDI 180 TE+RLS+ + LL ++ + T + NFD T +EP +LPA PN+L+NG+TGI+ G ATDI Sbjct: 365 TEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFPNLLVNGSTGISAGYATDI 424 Query: 181 PPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR 240 PPHNL EV AA+ +ID P +D+L++ + GPD+PT A II R EI+K YE G+G V Sbjct: 425 PPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGA-IIQGRDEIKKAYETGKGRVV 483 Query: 241 MRAVWKKE-----DGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPT 295 +R+ + E +VI+ +P++++ A ++++I N K+ + ++RDESD + Sbjct: 484 VRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVRVNNKVAGIAEVRDESDR-DGL 542 Query: 296 RLVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDG-RPAVKNLLEILSEWLVFR 354 R+ I + + + + V+N+LF TDL+ +Y N NM+ +D P ++ ILS ++ R Sbjct: 543 RIAIELKKD-ANTELVLNYLFKYTDLQINY--NFNMVAIDNFTPRQVGIVPILSSYIAHR 599 Query: 355 RDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIR---NEDEPKPALMSRFGLTE 411 R+ + R + EK KRLHI+EGL+ +DEVI +IR N+ + K L + TE Sbjct: 600 REVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALIRASENKADAKENLKVSYDFTE 659 Query: 412 TQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQA 471 QAEAI+ L+L L + + ++ E++EL ++ L I+ ER M NL+KKEL+ + Sbjct: 660 EQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLAAIIGDERTMYNLMKKELREVKKK 719 Query: 472 YGDDRRSPLQEREEA 486 + R S L++ +A Sbjct: 720 FATPRLSSLEDTAKA 734 >3LPX-A nrPDB Length = 500 Score = 596 bits (1537), Expect = e-170, Method: Composition-based stats. Identities = 207/496 (41%), Positives = 311/496 (62%), Gaps = 50/496 (10%) Query: 29 RALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAMVL 88 RALP + DGLKPV RR+++AM LG + + +KKSAR VGDV+GKYHPHGD+A Y+ +V Sbjct: 2 RALPDVRDGLKPVHRRVLFAMDVLGNDWNKAYKKSARVVGDVIGKYHPHGDTAVYDTIVR 61 Query: 89 MAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFD 148 MAQPFS RY LVDGQGN+G+ D S AAMRYTE R+SK + +L++L + T D+VPN+D Sbjct: 62 MAQPFSLRYMLVDGQGNFGSVDG-DSAAAMRYTEIRMSKIAHSILADLDKETVDFVPNYD 120 Query: 149 GTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLD 208 GT P ++P R+PN+L+NGT+GIAVGMAT+IPPHNL EV A +ALID + T +++L+ Sbjct: 121 GTEHIPAVMPTRVPNLLVNGTSGIAVGMATNIPPHNLTEVINACLALIDNSELTFEEILE 180 Query: 209 IVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMRAVWKKE------DGAVVISALPHQVS 262 + GPD+PT A II+ RA I + Y GRG +++RA + +++ LP+QV+ Sbjct: 181 HIPGPDFPT-AGIISGRAGIEEAYRTGRGKIKIRARASIDVHETTGKETIIVHELPYQVN 239 Query: 263 GARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTDLE 322 AR++E++A +++K+L + LRDESD ++ R+VI + V + V+N+L+ T ++ Sbjct: 240 KARLIEKMAELVKDKRLEGISALRDESD-KDGMRMVIEIKRGEVG-EVVLNNLYKLTQMQ 297 Query: 323 KSYRINLNMIGL-DGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLV 381 S+ LNM+ L +G+P + N+ E+L +++ RR+ V RR + L K R HILEGL + Sbjct: 298 VSFG--LNMVALTNGQPKIFNIKEMLEAFVLHRREVVTRRTIFELRKARDRAHILEGLSI 355 Query: 382 AFLNIDEVIEIIRNED---EPKPALMSR-------------------------------- 406 A NID +IE+I+N + E + L+S+ Sbjct: 356 ALANIDPIIEMIKNSNNRKESEEKLISQGWELGNVANMLSEAGNDAARPEWLEPEYGIRD 415 Query: 407 --FGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKE 464 + LT QA+AI++L+L L+ +E KI E L +L ILA+ ++ ++ +E Sbjct: 416 GLYYLTAEQAKAIVDLQLYKLSGMEHDKILSEYKALLDLIAELMHILATPARLMEVICEE 475 Query: 465 LQADAQAYGDDRRSPL 480 L A +GD+RR+ + Sbjct: 476 LVAIRDEFGDERRTEI 491 >4KPF-A nrPDB Length = 496 Score = 594 bits (1532), Expect = e-170, Method: Composition-based stats. Identities = 198/495 (40%), Positives = 309/495 (62%), Gaps = 16/495 (3%) Query: 1 MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKF 60 MS++ + ++L + + YS Y+I DRALP I DGLKPVQRRI+Y+M++ + Sbjct: 1 MSNI-QNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRILYSMNKDSNTFDKSY 59 Query: 61 KKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRY 120 +KSA++VG+++G +HPHGDS+ Y+AMV M+Q + R LV+ GN G+ D AAMRY Sbjct: 60 RKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMHGNNGSMDGDP-PAAMRY 118 Query: 121 TESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDI 180 TE+RLS+ + LL ++ + T + NFD T +EP +LPA PN+L+NG+TGI+ G ATDI Sbjct: 119 TEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFPNLLVNGSTGISAGYATDI 178 Query: 181 PPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR 240 PPHNL EV AA+ +ID P +D+L++ + GPD+PT A II R EI+K YE G+G V Sbjct: 179 PPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGA-IIQGRDEIKKAYETGKGRVV 237 Query: 241 MRAVWKKE-----DGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPT 295 +R+ + E +VI+ +P++++ A ++++I N K+ + ++RDESD + Sbjct: 238 VRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVRVNNKVAGIAEVRDESDR-DGL 296 Query: 296 RLVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDG-RPAVKNLLEILSEWLVFR 354 R+ I + + + + V+N+LF TDL+ +Y N NM+ +D P ++ ILS ++ R Sbjct: 297 RIAIELKKD-ANTELVLNYLFKYTDLQINY--NFNMVAIDNFTPRQVGIVPILSSYIAHR 353 Query: 355 RDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIR---NEDEPKPALMSRFGLTE 411 R+ + R + EK KRLHI+EGL+ +DEVI +IR N+ + K L + TE Sbjct: 354 REVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALIRASENKADAKENLKVSYDFTE 413 Query: 412 TQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQA 471 QAEAI+ L+L L + + ++ E++EL ++ L I+ ER M NL+KKEL+ + Sbjct: 414 EQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLAAIIGDERTMYNLMKKELREVKKK 473 Query: 472 YGDDRRSPLQEREEA 486 + R S L++ +A Sbjct: 474 FATPRLSSLEDTAKA 488 >3IFZ-A nrPDB Length = 508 Score = 593 bits (1529), Expect = e-170, Method: Composition-based stats. Identities = 197/494 (39%), Positives = 303/494 (61%), Gaps = 16/494 (3%) Query: 3 DMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKK 62 D E + + + + +Y++Y+M VI+ RALP + DGLKPV RR++YAM + G K Sbjct: 13 DRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAK 72 Query: 63 SARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTE 122 SAR+V + +G YHPHGD++ Y+++V MAQP+S RYPLVDGQGN+G+P AAMRYTE Sbjct: 73 SARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSP-GNDPPAAMRYTE 131 Query: 123 SRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPP 182 +RL+ + +L E+ + T D++PN+DG +QEP +LP+R PN+L NG+ GIAVGMAT+IPP Sbjct: 132 ARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNIPP 191 Query: 183 HNLREVAQAAIALIDQ----PKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGS 238 HNLRE+A A ++ + TL ++ V+GPD+PT I+ Y+ GRGS Sbjct: 192 HNLRELADAVFWALENHDADEEETLAAVMGRVKGPDFPTAGLIV-GSQGTADAYKTGRGS 250 Query: 239 VRMRAVWKKEDG-----AVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHEN 293 +RMR V + E+ ++VI+ LP+QV+ + IA Q+R+ KL + ++ D+S Sbjct: 251 IRMRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRV 310 Query: 294 PTRLVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVF 353 R+VI + + V V+N+L+ T L+ S+ N+ I +DG P L +++ ++ Sbjct: 311 GLRIVIEIKRDAV-AKVVINNLYKHTQLQTSFGANMLAI-VDGVPRTLRLDQLIRYYVDH 368 Query: 354 RRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDE---PKPALMSRFGLT 410 + D + RR YRL K +R HIL GL+ A +DEVI +IR + + L+ + Sbjct: 369 QLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAGLIELLDID 428 Query: 411 ETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQ 470 E QA+AIL+++LR LA LE +I + +++E E L+ ILA + +++ EL Sbjct: 429 EIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDELAEIVD 488 Query: 471 AYGDDRRSPLQERE 484 +GDDRR+ + E Sbjct: 489 RHGDDRRTRIIAAE 502 >2INR-A nrPDB Length = 514 Score = 591 bits (1524), Expect = e-169, Method: Composition-based stats. Identities = 195/497 (39%), Positives = 315/497 (63%), Gaps = 16/497 (3%) Query: 1 MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKF 60 +S++ + L+L + + + YS Y+I +RALP + DGLKPVQRRI+YAM G F Sbjct: 24 VSEIIQDLSLEDVLGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYAMYSSGNTHDKNF 83 Query: 61 KKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRY 120 +KSA+TVGDV+G+YHPHGDS+ YEAMV ++Q + R+ L++ GN G+ D+ AAMRY Sbjct: 84 RKSAKTVGDVIGQYHPHGDSSVYEAMVRLSQDWKLRHVLIEMHGNNGSIDNDP-PAAMRY 142 Query: 121 TESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDI 180 TE++LS +E LL ++ + T ++PN+D T EP +LP+R PN+L+NG+TGI+ G ATDI Sbjct: 143 TEAKLSLLAEELLRDINKETVSFIPNYDDTTLEPMVLPSRFPNLLVNGSTGISAGYATDI 202 Query: 181 PPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR 240 PPHNL EV QA + ID P T++QL+ ++GPD+PT I I+K YE+G+G + Sbjct: 203 PPHNLAEVIQATLKYIDNPDITVNQLMKYIKGPDFPTGGIIQG-IDGIKKAYESGKGRII 261 Query: 241 MRAVWKKED-----GAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPT 295 +R+ ++E ++I+ +P++V+ + ++++I +KK+ + ++RDE+D Sbjct: 262 VRSKVEEETLRNGRKQLIITEIPYEVNKSSLVKRIDELRADKKVDGIVEVRDETDR-TGL 320 Query: 296 RLVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGL-DGRPAVKNLLEILSEWLVFR 354 R+ I + + V+ + + N+L+ +DL+ SY N NM+ + DGRP + + +I+ +L + Sbjct: 321 RIAIELKKD-VNSESIKNYLYKNSDLQISY--NFNMVAISDGRPKLMGIRQIIDSYLNHQ 377 Query: 355 RDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIR---NEDEPKPALMSRFGLTE 411 + V R + L+ KR+HI+EGL+ A +D+VIE+IR N+ + K L+ + TE Sbjct: 378 IEVVANRTKFELDNAEKRMHIVEGLIKALSILDKVIELIRSSKNKRDAKENLIEVYEFTE 437 Query: 412 TQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQA 471 QAEAI+ L+L L + + + GE ELE QL+ IL + + N++K+EL + Sbjct: 438 EQAEAIVMLQLYRLTNTDIVALEGEHKELEALIKQLRHILDNHDALLNVIKEELNEIKKK 497 Query: 472 YGDDRRSPLQ-EREEAK 487 + +R S ++ E EE K Sbjct: 498 FKSERLSLIEAEIEEIK 514 >1ZVT-A nrPDB Length = 256 Score = 540 bits (1390), Expect = e-153, Method: Composition-based stats. Identities = 256/256 (100%), Positives = 256/256 (100%) Query: 497 SEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAID 556 SEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAID Sbjct: 1 SEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAID 60 Query: 557 PITLPSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNR 616 PITLPSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNR Sbjct: 61 PITLPSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNR 120 Query: 617 AGKALITLPENAHVMPPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPS 676 AGKALITLPENAHVMPPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPS Sbjct: 121 AGKALITLPENAHVMPPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPS 180 Query: 677 AEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGERGRRGTLMRGLQRIDR 736 AEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGERGRRGTLMRGLQRIDR Sbjct: 181 AEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGERGRRGTLMRGLQRIDR 240 Query: 737 VEIDSPRRASSGDSEE 752 VEIDSPRRASSGDSEE Sbjct: 241 VEIDSPRRASSGDSEE 256 >1BJT-A nrPDB Length = 793 Score = 349 bits (896), Expect = 2e-96, Method: Composition-based stats. Identities = 88/385 (22%), Positives = 162/385 (42%), Gaps = 53/385 (13%) Query: 9 ALHEFTENAYLNYSMYVIM----DRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSA 64 L E + ++N + + R++P + DG KP QR+++Y + L + K + A Sbjct: 258 TLKEIPISDFINKELILFSLADNIRSIPNVLDGFKPGQRKVLYGCFKKNLKSELKVAQLA 317 Query: 65 RTVGDVLGKYHPHGDSACYEAMVLMAQPF--SYRYPLVDGQGNWGAP-DDPKSFAAMRYT 121 V + YH HG+ + + ++ +AQ F S L+ G +G K AA RY Sbjct: 318 PYVSECT-AYH-HGEQSLAQTIIGLAQNFVGSNNIYLLLPNGAFGTRATGGKDAAAARYI 375 Query: 122 ESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIP 181 + L+K + + ++ + T EP+ LP IL+NG GI G +T IP Sbjct: 376 YTELNKLTRKIFHPADDPLYKYIQEDEKT-VEPEWYLPILPMILVNGAEGIGTGWSTYIP 434 Query: 182 PHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRM 241 P N E+ + L++ + L+Q+ +G E EI + G + Sbjct: 435 PFNPLEIIKNIRHLMNDEE--LEQMHPWFRGWTGTIE--------EIEPLRYRMYGRIEQ 484 Query: 242 RAVWKKEDGAVVISALPHQVSGARVLEQIAAQM--RNKKLPMVDDLRDESDHENPTRLVI 299 D + I+ LP + + + E + + +K P + D+ E H++ + +I Sbjct: 485 IG-----DNVLEITELPARTWTSTIKEYLLLGLSGNDKIKPWIKDM--EEQHDDNIKFII 537 Query: 300 ------VPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDGRPAVK---NLLEILSEW 350 + ++ ++ + L + L +NM+ D +K ++ EILSE+ Sbjct: 538 TLSPEEMAKTRKIGFYERFK-LISPISL-------MNMVAFDPHGKIKKYNSVNEILSEF 589 Query: 351 LVF-------RRDTVRRRLNYRLEK 368 R+D + RL + +EK Sbjct: 590 YYVRLEYYQKRKDHMSERLQWEVEK 614 >6CA8-A nrPDB Length = 751 Score = 335 bits (859), Expect = 4e-92, Method: Composition-based stats. Identities = 112/526 (21%), Positives = 209/526 (39%), Gaps = 74/526 (14%) Query: 6 ERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSAR 65 + L+ ++F + YS Y +R++P I DG KP QR+++Y + L K + Sbjct: 248 KDLSYYDFVNKELIYYSRYD-TERSIPNIMDGWKPGQRKVLYGCFKRNLRNECKVAQLVG 306 Query: 66 TVGDVLGKYHPHGDSACYEAMVLMAQPF--SYRYPLVDGQGNWGAP-DDPKSFAAMRYTE 122 + + YH HG+S+ + ++ MAQ F S ++ G +G+ + K +A RY Sbjct: 307 YIAE-HSAYH-HGESSLQQTIINMAQTFVGSNNINFLEPCGQFGSRKEGGKDASAARYIF 364 Query: 123 SRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPP 182 ++L+ + + +E ++ N +G EP+ +P IL+NG GI G ++ IP Sbjct: 365 TKLASSTRSIFNEYDDPILKYL-NEEGQKIEPQYYIPVIPTILVNGCEGIGTGYSSFIPN 423 Query: 183 HNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMR 242 +N +++ ID K +++ I P Y R E NG+ Sbjct: 424 YNYKDI-------IDNIKRYINKEPLIPMVPWYKD----FKGRIE-----SNGKTGYETI 467 Query: 243 AVWKKEDGA-VVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLV-IV 300 + K D + I+ LP + E + + ++K ++ D D S HE+ + + Sbjct: 468 GIINKIDNDTLEITELPIKKWTQDYKEFLEELLTDEKHQLILDYIDNSSHEDICFTIKMD 527 Query: 301 PRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNL---LEILSEWLVFRRDT 357 P + ++ + +F KS NM D ++ L+IL E+ R Sbjct: 528 PAKLQKAEEEGLEKVFKL----KSTLTTTNMTLFDPNLKLQRYSTELDILKEFCYQRLKA 583 Query: 358 VRRRLNYRLEKVLKRLHILEGLLVAFLNI--DEVI------------------------- 390 R +Y + K+ K I+ L I +E+I Sbjct: 584 YENRKSYLISKLEKEKRIISNKTKFILAIVNNELIVNKKKKKVLVEELYRKGYDPYKDIN 643 Query: 391 ----------EIIRNEDEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSEL 440 E++ D P+ G+T + +L + + L + + + E Sbjct: 644 KIKKEEIFEQELLDAADNPEDNEEIIAGITVKDYDYLLSMPIFSLTLEKVEDLLTQLKEK 703 Query: 441 EKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPLQEREEA 486 E+E + L+ I + + K+++ +A R L REE+ Sbjct: 704 ERELEILRNI-----TVETMWLKDIEKVEEAIEFQRNVELSNREES 744 >5GWJ-A nrPDB Length = 803 Score = 288 bits (736), Expect = 7e-78, Method: Composition-based stats. Identities = 106/527 (20%), Positives = 197/527 (37%), Gaps = 80/527 (15%) Query: 9 ALHEFTENAYLNYSMYVIMD----RALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSA 64 A T N ++N + + + R++P + DG KP QR++++ + K + A Sbjct: 287 ATKHLTYNDFINKELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLA 346 Query: 65 RTVGDVLGKYHPHGDSACYEAMVLMAQPF--SYRYPLVDGQGNWGAP-DDPKSFAAMRYT 121 +V + + YH HG+ A +V +AQ F S L+ G +G K A+ RY Sbjct: 347 GSVAE-MSAYH-HGEQALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYI 404 Query: 122 ESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIP 181 + LS + LL + ++ + D EP+ +P +L+NG GI G A +P Sbjct: 405 FTMLSTLARLLFPAVDDNLLKFLYD-DNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLP 463 Query: 182 PHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRM 241 ++ RE+ ++D L P+Y I E G+ + Sbjct: 464 NYDAREIVNNVRRMLD-------GLDPHPMLPNYKNFKGTIQ---------ELGQNQYAV 507 Query: 242 RAVWKKED-GAVVISALPHQVSGARVLEQIAAQM---RNKKLPMVDDLRDESDHENPTRL 297 D V I+ LP + EQ+ M +K ++ D + E + + Sbjct: 508 SGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTPALISDYK-EYHTDTTVKF 566 Query: 298 VIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDGRP---AVKNLLEILSEWLVFR 354 V+ ++ L L+ + N +M+ D + + +IL E+ R Sbjct: 567 VVKMTEEKL-AQAEAAGLHKVFKLQTTLTCN-SMVLFDHMGCLKKYETVQDILKEFFDLR 624 Query: 355 RDTVRRRLNY-------RLEKVLKRLH-ILEGLLVAFLNID----EVIEIIRN---EDEP 399 R + K+ + ILE + + ++I+++ E +P Sbjct: 625 LSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKKDLIQMLVQRGYESDP 684 Query: 400 ----KPALMSRFGLTETQAE-----------------AILELKLRHLAKLEEMKIRGEQS 438 K A ETQ + IL + L L K + ++ ++ Sbjct: 685 VKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEKVEELIKQRD 744 Query: 439 ELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPLQEREE 485 +E + L+ + ++L K++L A + + QERE+ Sbjct: 745 AKGREVNDLKR-----KSPSDLWKEDLAAFVEELD---KVESQERED 783 >4FM9-A nrPDB Length = 763 Score = 288 bits (736), Expect = 8e-78, Method: Composition-based stats. Identities = 82/371 (22%), Positives = 147/371 (39%), Gaps = 34/371 (9%) Query: 9 ALHEFTENAYLNYSMYVIMD----RALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSA 64 T N ++N + + + R++P + DGLKP QR++++ + K + A Sbjct: 259 TTTYLTYNDFINKELILFSNSDNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLA 318 Query: 65 RTVGDVLGKYHPHGDSACYEAMVLMAQPF--SYRYPLVDGQGNWGAP-DDPKSFAAMRYT 121 +V + + YH HG+ + ++ +AQ F S L+ G +G K A+ RY Sbjct: 319 GSVAE-MSSYH-HGEMSLMMTIINLAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYI 376 Query: 122 ESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIP 181 + LS + LL T ++ + D EP+ +P +L+NG GI G + IP Sbjct: 377 FTMLSSLARLLFPPKDDHTLKFLYD-DNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIP 435 Query: 182 PHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRM 241 ++RE+ L+D + P P+ + E+ G V + Sbjct: 436 NFDVREIVNNIRRLMDGEE----------PLPMLPSYKNFKGTIEELAPNQYVISGEVAI 485 Query: 242 RAVWKKEDGAVVISALPHQVSGARVLEQIAAQM---RNKKLPMVDDLRDESDHENPTRLV 298 + IS LP + EQ+ M K P++ D R E + + V Sbjct: 486 -----LNSTTIEISELPVRTWTQTYKEQVLEPMLNGTEKTPPLITDYR-EYHTDTTVKFV 539 Query: 299 IVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDGRPAVK---NLLEILSEWLVFRR 355 + ++ + + L L+ S N +M+ D +K +L+IL ++ R Sbjct: 540 VKMTEEKLAEAERVG-LHKVFKLQTSLTCN-SMVLFDHVGCLKKYDTVLDILRDFFELRL 597 Query: 356 DTVRRRLNYRL 366 R + L Sbjct: 598 KYYGLRKEWLL 608 >4ELZ-A nrPDB Length = 153 Score = 131 bits (330), Expect = 9e-31, Method: Composition-based stats. Identities = 52/140 (37%), Positives = 63/140 (45%), Gaps = 37/140 (26%) Query: 351 LVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEP---KPALMSR- 406 LV R + RR + L K R HILEGL +A NIDE+IE+I+N P K L+SR Sbjct: 14 LVPRGSHMTRRTIFELRKARDRAHILEGLALALANIDEIIELIKNAPTPAEAKEGLISRG 73 Query: 407 ---------------------------------FGLTETQAEAILELKLRHLAKLEEMKI 433 + LTE QA+AILEL+L L LE KI Sbjct: 74 WDLGNVASMLERAGTDAARPDWLEPEFGIREGKYFLTEQQAQAILELRLHRLTGLEHEKI 133 Query: 434 RGEQSELEKERDQLQGILAS 453 E L E +L ILAS Sbjct: 134 LDEYKALLDEIAELMHILAS 153 >4ELY-A nrPDB Length = 156 Score = 130 bits (327), Expect = 2e-30, Method: Composition-based stats. Identities = 47/143 (32%), Positives = 63/143 (44%), Gaps = 37/143 (25%) Query: 351 LVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEP---KPALMS-- 405 LV R + RR + L K R HILE L VA NID +IE+IR+ P K AL++ Sbjct: 14 LVPRGSHMTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANP 73 Query: 406 --------------------------------RFGLTETQAEAILELKLRHLAKLEEMKI 433 + LTE QA+AIL+L+L+ L LE K+ Sbjct: 74 WQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKL 133 Query: 434 RGEQSELEKERDQLQGILASERK 456 E EL + +L IL S + Sbjct: 134 LDEYKELLDQIAELLRILGSADR 156 >1X75-A nrPDB Length = 132 Score = 119 bits (299), Expect = 4e-27, Method: Composition-based stats. Identities = 44/132 (33%), Positives = 58/132 (43%), Gaps = 37/132 (28%) Query: 359 RRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEP---KPALMSR--------- 406 RR + L K R HILE L VA NID +IE+IR+ P K AL++ Sbjct: 1 TRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAA 60 Query: 407 -------------------------FGLTETQAEAILELKLRHLAKLEEMKIRGEQSELE 441 + LTE QA+AIL+L+L+ L LE K+ E EL Sbjct: 61 MLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELL 120 Query: 442 KERDQLQGILAS 453 + +L IL S Sbjct: 121 DQIAELLRILGS 132 >1K2W-A nrPDB Length = 256 Score = 35.4 bits (80), Expect = 0.085, Method: Composition-based stats. Identities = 18/55 (32%), Positives = 28/55 (50%), Gaps = 2/55 (3%) Query: 631 MPPVV--IEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGE 683 + P+V ++ D L AI +G + M ++ G+G KIIN+ S RGE Sbjct: 92 LAPIVEITRESYDRLFAINVSGTLFMMQAVARAMIAGGRGGKIINMASQAGRRGE 146 >4E6P-A nrPDB Length = 259 Score = 35.0 bits (79), Expect = 0.12, Method: Composition-based stats. Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 5/84 (5%) Query: 631 MPPVV--IEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQ 688 + P+V ++ + L AI AG + + +++G+G KIIN+ S RGE L Sbjct: 95 LAPIVEITRESYEKLFAINVAGTLFTLQAAARQMIAQGRGGKIINMASQAGRRGE-ALVA 153 Query: 689 LYVLPPQS--TLTIHVGKRKIKLR 710 +Y + +LT G IK R Sbjct: 154 IYCATKAAVISLTQSAGLDLIKHR 177 >5AMO-A nrPDB Length = 471 Score = 34.3 bits (77), Expect = 0.19, Method: Composition-based stats. Identities = 30/150 (20%), Positives = 58/150 (38%), Gaps = 22/150 (14%) Query: 339 AVKNLLEILSEW--LVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEV------- 389 K L ++L + + + + RR L+ V K + ++GL F ++E Sbjct: 74 RTKQLRQLLEKVQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLETKFKQVEESHKQHLAR 133 Query: 390 -IEIIRNEDEPKPALMSRFGLTETQAEAILELKLRH--------LAKLEEMKIRGEQSEL 440 + I+ + + L+ L E +A+A L L+ + L +L+E + EL Sbjct: 134 QFKAIKAKMDELRPLIPV--LEEYKADAKLVLQFKEEVQNLTSVLNELQEEIGAYDYDEL 191 Query: 441 EKERDQLQGILASERKMNNLLKKELQADAQ 470 + L+ L M L +L + Sbjct: 192 QSRVSNLEERL--RACMQKLACGKLTGISD 219 >2VDU-B nrPDB Length = 450 Score = 34.3 bits (77), Expect = 0.21, Method: Composition-based stats. Identities = 16/63 (25%), Positives = 33/63 (52%), Gaps = 3/63 (4%) Query: 537 GKSNQPVVFVDSTGRSYAIDPITLPSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLM 596 + + V+ D G Y+ID ++P + EP+ G +++ T H++ +SD + ++ Sbjct: 158 AEDDTTVIIADKFGDVYSIDINSIPEEKFTQEPILGHVSM---LTDVHLIKDSDGHQFII 214 Query: 597 ASD 599 SD Sbjct: 215 TSD 217 >2PCN-A nrPDB Length = 161 Score = 34.3 bits (77), Expect = 0.21, Method: Composition-based stats. Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 6/87 (6%) Query: 657 VSDLPQLSKGKGNKIINIPSAEAARGEDGL---AQLYVLPPQSTLTIH-VGKRKIKLRPE 712 V +LP S G G ++ + P A ED + L +PP + L + G R++ L + Sbjct: 16 VCELPFQSYG-GKRMFSGPIATVDVFEDNVLVREALETVPPGTVLVVDGKGSRRVALLGD 74 Query: 713 ELQKVTGERGRRGTLMRGLQRIDRVEI 739 L ++ ERG G ++ G R D EI Sbjct: 75 RLAQIACERGLAGVIIHGCIR-DSAEI 100 >5MLZ-A nrPDB Length = 374 Score = 33.1 bits (74), Expect = 0.43, Method: Composition-based stats. Identities = 32/185 (17%), Positives = 65/185 (35%), Gaps = 30/185 (16%) Query: 180 IPPHNLREVAQAAIALIDQPKTTLDQLLDIV------QGPDYPTEAEIITSRAEIRKIYE 233 IP +N RE + + ID L+ + +V + + E IR+ E Sbjct: 29 IPTYNERENLEELFSRIDNALQGLNYEIVVVDDDSPDRTWEKAQELSSKYPVKVIRRTKE 88 Query: 234 NGRGSVRMRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHEN 293 G S +R + V+ Q V+ ++ ++N SD Sbjct: 89 KGLSSAVIRGFKEASGDVFVVMDADLQ-HPPEVIPKLIEAIKNG-----------SDIAI 136 Query: 294 PTRLVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVF 353 +R V + +V+ L + + M+G P ++++ + +S + Sbjct: 137 GSRYV---KGGKVENWPFYRKLISKGAI---------MVGRIALPKIRDIKDPVSGFFAL 184 Query: 354 RRDTV 358 R++ V Sbjct: 185 RKEVV 189 >5J6F-A nrPDB Length = 368 Score = 33.1 bits (74), Expect = 0.46, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 29/68 (42%) Query: 435 GEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPLQEREEAKAMSEHDM 494 EL D++ L L +E+ +A G R P++ER+ +SEH+ Sbjct: 4 ERLDELRARVDEINLQLLKLINERGRLVQEIGKIKEAQGTHRYDPVRERKMLDLISEHND 63 Query: 495 LPSEPVTI 502 P E T+ Sbjct: 64 GPFETSTL 71 >5MRE-R nrPDB Length = 337 Score = 32.7 bits (73), Expect = 0.58, Method: Composition-based stats. Identities = 21/131 (16%), Positives = 49/131 (37%), Gaps = 11/131 (8%) Query: 316 FATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHI 375 +L SY I + +G P +++ +L RR ++ EK Sbjct: 154 IKDIELATSYLIRVRASLKNGYP-IEDARFNSRYYLKEEERLKARRESWTNEK------- 205 Query: 376 LEGLLVAFLNIDEVIEIIRNEDEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRG 435 L + IDE +++ + L ++E + +A+ L L K + ++ + Sbjct: 206 ---LSESLSKIDECSDLLNSSTSFNNKLELHQYISEQEKQALKAKLLEDLEKSQHLETKK 262 Query: 436 EQSELEKERDQ 446 +++ ++ Sbjct: 263 DKNYIKALFKD 273 >5EXR-B nrPDB Length = 509 Score = 32.3 bits (72), Expect = 0.80, Method: Composition-based stats. Identities = 19/115 (16%), Positives = 37/115 (32%), Gaps = 16/115 (13%) Query: 401 PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQS-ELEKERDQLQGILA---SERK 456 L + Q ++ LE +LR L + E LA SE Sbjct: 57 ENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEEL 116 Query: 457 MNNLLKKELQADAQAYGDDRRSPLQE------------REEAKAMSEHDMLPSEP 499 +++E+ + + +Q+ +E K + E +++ S P Sbjct: 117 RRWFIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSP 171 >4BPX-B nrPDB Length = 269 Score = 32.3 bits (72), Expect = 0.80, Method: Composition-based stats. Identities = 19/115 (16%), Positives = 37/115 (32%), Gaps = 16/115 (13%) Query: 401 PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQS-ELEKERDQLQGILA---SERK 456 L + Q ++ LE +LR L + E LA SE Sbjct: 73 ENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEEL 132 Query: 457 MNNLLKKELQADAQAYGDDRRSPLQE------------REEAKAMSEHDMLPSEP 499 +++E+ + + +Q+ +E K + E +++ S P Sbjct: 133 RRWFIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSP 187 >4YDH-A nrPDB Length = 433 Score = 32.3 bits (72), Expect = 0.81, Method: Composition-based stats. Identities = 15/92 (16%), Positives = 33/92 (35%), Gaps = 20/92 (21%) Query: 383 FLNIDEVIEIIRNEDEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEK 442 NI +V ++ + + L L E A L ++R ++E Sbjct: 353 LDNIFDVGALLEDTETKNAVLEHMEELQEQVA-------------LLTERLRDAENESMA 399 Query: 443 ERDQLQGILASERKMNNLLKKELQADAQAYGD 474 + +L+ L+ +KEL+ + + + Sbjct: 400 KIAELEKQLSQA-------RKELETLRERFSE 424 >4G3N-A nrPDB Length = 327 Score = 32.0 bits (71), Expect = 0.90, Method: Composition-based stats. Identities = 39/197 (19%), Positives = 80/197 (40%), Gaps = 32/197 (16%) Query: 499 PVTIVLSQMGWVRSAKGHDIDAP------GLNYKAGDSFKAAVKGKSNQPVVFVDSTGRS 552 P ++ ++ G V+ +K D D+ +N + D AV + ++ V + G+S Sbjct: 110 PYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQS 169 Query: 553 YAIDPITLPSARGQGEPLTGKLTLPPGATVDHMLMESDDQ-----------KLLMASDAG 601 T + R G +G V M DD+ LL+A+ G Sbjct: 170 IRFSA-TDEALRPMGRATSG---------VQGMRFNIDDRLLSLNVVREGTYLLVATSGG 219 Query: 602 YGFVCTFNDLVARNRAGKALITL---PENAHVMPPVVIEDASDMLLAITQAGRMLMFPVS 658 Y + + R GK ++T+ ++ ++++D S+ L A+T G ++ Sbjct: 220 YAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSE-LYAVTSGGGVIRTAAR 278 Query: 659 DLPQLSK-GKGNKIINI 674 + + + KG +++N+ Sbjct: 279 QVRKAGRQTKGVRLMNL 295 >4BPU-B nrPDB Length = 253 Score = 32.0 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 19/115 (16%), Positives = 37/115 (32%), Gaps = 16/115 (13%) Query: 401 PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQS-ELEKERDQLQGILA---SERK 456 L + Q ++ LE +LR L + E LA SE Sbjct: 57 ENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEEL 116 Query: 457 MNNLLKKELQADAQAYGDDRRSPLQE------------REEAKAMSEHDMLPSEP 499 +++E+ + + +Q+ +E K + E +++ S P Sbjct: 117 RRWFIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSP 171 >5YZ0-C nrPDB Length = 791 Score = 31.6 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 32/68 (47%), Gaps = 1/68 (1%) Query: 427 KLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSP-LQEREE 485 E ++ + EL+++ ++ + + +L+ L + RRS L E+E+ Sbjct: 111 NFELEVLQAQYKELKEKMKVMEEEVLIKNGEIKILRDSLHQTESVLEEQRRSHFLLEQEK 170 Query: 486 AKAMSEHD 493 +A+S+ + Sbjct: 171 TQALSDKE 178 >2CSB-A nrPDB Length = 519 Score = 31.6 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 39/294 (13%), Positives = 94/294 (31%), Gaps = 20/294 (6%) Query: 179 DIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQ-GPDYPTEAEIITSRAEIRKIYENGRG 237 ++PP E + +++L+I++ P P + I R + G Sbjct: 161 EVPPEMAGEFERLIERYDVPIDEKEERILEILRENPWTPHDE--IARRLGLSVSEVEGEK 218 Query: 238 SVRMRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRL 297 ++ VV + + V + + + + H R Sbjct: 219 DPESSGIYSLWSRVVVNIEYDERTAKRHVKRR-DRLLEELYEHLEELSERYLRHPLTRRW 277 Query: 298 VIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDT 357 ++ + + + + L+ Y I ++ R ++ I + +D Sbjct: 278 IVEHKRDIMRRYLEQRIVECALKLQDRYGIREDVALCLARAFDGSISMIATTPYRTLKDV 337 Query: 358 VRRRLNYRLEKVLKR-LHILEGLLVAFLNIDEVIE-------IIRNEDEPKPALMSRFGL 409 + V + +++ ++ DE+IE I+ + E + L Sbjct: 338 CPDLTLEEAKSVNRTLATLIDEHGLSPDAADELIEHFESIAGILATDLEEIERMYEEGRL 397 Query: 410 TETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKK 463 +E A +E++L L K E + K ++L + ++ L ++ Sbjct: 398 SEEAYRAAVEIQLAELTKKEGVG--------RKTAERLLRAFGNPERVKQLARE 443 >4GFJ-A nrPDB Length = 685 Score = 31.2 bits (69), Expect = 1.9, Method: Composition-based stats. Identities = 39/294 (13%), Positives = 94/294 (31%), Gaps = 20/294 (6%) Query: 179 DIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQ-GPDYPTEAEIITSRAEIRKIYENGRG 237 ++PP E + +++L+I++ P P + I R + G Sbjct: 161 EVPPEMAGEFERLIERYDVPIDEKEERILEILRENPWTPHDE--IARRLGLSVSEVEGEK 218 Query: 238 SVRMRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRL 297 ++ VV + + V + + + + H R Sbjct: 219 DPESSGIYSLWSRVVVNIEYDERTAKRHVKRR-DRLLEELYEHLEELSERYLRHPLTRRW 277 Query: 298 VIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDT 357 ++ + + + + L+ Y I ++ R ++ I + +D Sbjct: 278 IVEHKRDIMRRYLEQRIVECALKLQDRYGIREDVALCLARAFDGSISMIATTPYRTLKDV 337 Query: 358 VRRRLNYRLEKVLKR-LHILEGLLVAFLNIDEVIE-------IIRNEDEPKPALMSRFGL 409 + V + +++ ++ DE+IE I+ + E + L Sbjct: 338 CPDLTLEEAKSVNRTLATLIDEHGLSPDAADELIEHFESIAGILATDLEEIERMYEEGRL 397 Query: 410 TETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKK 463 +E A +E++L L K E + K ++L + ++ L ++ Sbjct: 398 SEEAYRAAVEIQLAELTKKEGVG--------RKTAERLLRAFGNPERVKQLARE 443 >5HM5-A nrPDB Length = 854 Score = 31.2 bits (69), Expect = 2.0, Method: Composition-based stats. Identities = 39/294 (13%), Positives = 94/294 (31%), Gaps = 20/294 (6%) Query: 179 DIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQ-GPDYPTEAEIITSRAEIRKIYENGRG 237 ++PP E + +++L+I++ P P + I R + G Sbjct: 161 EVPPEMAGEFERLIERYDVPIDEKEERILEILRENPWTPHDE--IARRLGLSVSEVEGEK 218 Query: 238 SVRMRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRL 297 ++ VV + + V + + + + H R Sbjct: 219 DPESSGIYSLWSRVVVNIEYDERTAKRHVKRR-DRLLEELYEHLEELSERYLRHPLTRRW 277 Query: 298 VIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDT 357 ++ + + + + L+ Y I ++ R ++ I + +D Sbjct: 278 IVEHKRDIMRRYLEQRIVECALKLQDRYGIREDVALCLARAFDGSISMIATTPYRTLKDV 337 Query: 358 VRRRLNYRLEKVLKR-LHILEGLLVAFLNIDEVIE-------IIRNEDEPKPALMSRFGL 409 + V + +++ ++ DE+IE I+ + E + L Sbjct: 338 CPDLTLEEAKSVNRTLATLIDEHGLSPDAADELIEHFESIAGILATDLEEIERMYEEGRL 397 Query: 410 TETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKK 463 +E A +E++L L K E + K ++L + ++ L ++ Sbjct: 398 SEEAYRAAVEIQLAELTKKEGVG--------RKTAERLLRAFGNPERVKQLARE 443 >3VR3-D nrPDB Length = 465 Score = 30.8 bits (68), Expect = 2.1, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 25/57 (43%), Gaps = 4/57 (7%) Query: 433 IRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPLQEREEAKAM 489 + E +++ L + K++ + +EL G+ RR + E +E KAM Sbjct: 8 MIKEYRTIKEVVGPLMAV----EKVSGVKYEELIEVRMQNGEIRRGQVLEVQEDKAM 60 >1XI9-A nrPDB Length = 406 Score = 30.4 bits (67), Expect = 2.7, Method: Composition-based stats. Identities = 25/106 (23%), Positives = 41/106 (38%), Gaps = 14/106 (13%) Query: 97 YPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKM 156 +++ GA D K+ E L+ E + + D + ++G P Sbjct: 178 IAVINPNNPTGALYDKKT------LEEILNIAGEYEIPVISDEIYDLM-TYEGEHISPGS 230 Query: 157 LPARLPNILLNG------TTGIAVGMATDIPPHN-LREVAQAAIAL 195 L +P I++NG TG +G + P N L EV +A L Sbjct: 231 LTKDVPVIVMNGLSKVYFATGWRLGYMYFVDPENKLSEVREAIDRL 276 >2QAG-C nrPDB Length = 418 Score = 30.4 bits (67), Expect = 3.3, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 23/47 (48%) Query: 430 EMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDR 476 EMK++ + +L+ +LQ +K KEL+ + + D++ Sbjct: 343 EMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDEK 389 >3EUH-A nrPDB Length = 440 Score = 30.0 bits (66), Expect = 4.2, Method: Composition-based stats. Identities = 24/139 (17%), Positives = 46/139 (33%), Gaps = 21/139 (15%) Query: 342 NLLEILSEWLVFRRDTVRRRLNYRLEKVLKRL----------------HILEGLLVAFLN 385 NLL I + RL + L+ L R+ H+ + + A Sbjct: 232 NLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIGYDRHVHKFIRTAIDM 291 Query: 386 IDEVIEIIRNEDEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRG-----EQSEL 440 + R + + LT A+ +L+++ +A +E E E Sbjct: 292 DKNRVFAQRLRQSVQTYFDEPWALTYANADRLLDMRDEEMALRDEEVTGELPEDLEYEEF 351 Query: 441 EKERDQLQGILASERKMNN 459 + R+QL I+ + + Sbjct: 352 NEIREQLAAIIEEQLAVYK 370 >2TMA-A nrPDB Length = 284 Score = 30.0 bits (66), Expect = 4.3, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 46/104 (44%), Gaps = 5/104 (4%) Query: 365 RLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPKPALMSRFGLTETQAEAILELKLRH 424 LE+ +R + EG ++E I+ + N + A ++ E + E +++ Sbjct: 175 DLERAEERAELSEG---KCAELEEEIKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDK 231 Query: 425 LAKLEEMKIRGEQS--ELEKERDQLQGILASERKMNNLLKKELQ 466 L + E E+S +LEK D L+ L +++ + +EL Sbjct: 232 LKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELD 275 >3R3S-A nrPDB Length = 294 Score = 29.7 bits (65), Expect = 4.9, Method: Composition-based stats. Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Query: 211 QGPDYPTEAEIITSRAEIRKIYENGRGSVRMRAV---WKKEDGAVVISALPHQVSGARVL 267 PD ++ + + R + RK G S RA + +E V I+ LP + A+ + Sbjct: 32 PVPDCGEKSYVGSGRLKDRKALVTGGDSGIGRAAAIAYAREGADVAINYLPAEEEDAQQV 91 Query: 268 EQIAAQMRNKKLPMVDDLRDES 289 + + + K + + DL DES Sbjct: 92 KALIEECGRKAVLLPGDLSDES 113 >2I1J-A nrPDB Length = 575 Score = 29.7 bits (65), Expect = 5.0, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 43/112 (38%), Gaps = 8/112 (7%) Query: 360 RRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPKPALMSRFGLTETQAEAILE 419 R++ +E+ LL A I + E +R K L R E QA Sbjct: 345 RQMQEEMERSQA------NLLEAQDMILRLEEQLRQLQAAKEELEQRQN--ELQAMMQRL 396 Query: 420 LKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQA 471 + +++ E K+ E ++E ++Q + + L++E++ + Sbjct: 397 EETKNMEAAERQKLEDEIRAKQEEVSRIQQEVELKDSETRRLQEEVEDARRK 448 >3JVD-A nrPDB Length = 333 Score = 29.7 bits (65), Expect = 5.3, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 27/54 (50%), Gaps = 12/54 (22%) Query: 172 IAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSR 225 + G+ T +PPH E+ + A+ L L+D+++ P+ PT ++ + Sbjct: 275 VGAGITTFVPPHE--EMGKEAVRL----------LVDLIENPELPTGDVVLQGQ 316 >5JQE-A nrPDB Length = 565 Score = 28.9 bits (63), Expect = 7.7, Method: Composition-based stats. Identities = 30/161 (18%), Positives = 61/161 (37%), Gaps = 20/161 (12%) Query: 342 NLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNID------EVIEIIRN 395 N+ ++ + W R + R + E L A ++D ++ E + + Sbjct: 344 NIPQMSAFWYAVRTAVI--------NAASGRQTVDEALAAAQTHMDFSRNLYDIGEQLDS 395 Query: 396 EDEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGE-----QSELEKERDQLQGI 450 ED +S + + + E I + L +L+E ++ E EL ++L + Sbjct: 396 EDLASLKFLSLDYIPQRKQEPIKD-ALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLL 454 Query: 451 LASERKMNNLLKKELQADAQAYGDDRRSPLQEREEAKAMSE 491 + +++ELQ +A R L + E + SE Sbjct: 455 ITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSE 495 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.133 0.348 Lambda K H 0.267 0.0411 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 27,606,361 Number of Sequences: 36641 Number of extensions: 1116485 Number of successful extensions: 3879 Number of sequences better than 10.0: 62 Number of HSP's better than 10.0 without gapping: 54 Number of HSP's successfully gapped in prelim test: 47 Number of HSP's that attempted gapping in prelim test: 3634 Number of HSP's gapped (non-prelim): 130 length of query: 752 length of database: 10,336,785 effective HSP length: 104 effective length of query: 648 effective length of database: 6,526,121 effective search space: 4228926408 effective search space used: 4228926408 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 63 (28.9 bits)