BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P0AF03 (195 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1DI7-A nrPDB 394 e-110 3MCI-A nrPDB 199 4e-52 2F7Y-A nrPDB 199 7e-52 4XCW-A nrPDB 187 2e-48 4NWO-A nrPDB 179 5e-46 2IS8-A nrPDB 109 6e-25 1IHC-A nrPDB 93 9e-20 1O8Q-A nrPDB 85 2e-17 4LHB-A nrPDB 69 2e-12 1Y5E-A nrPDB 65 3e-11 1R2K-B nrPDB 57 4e-09 3IWT-A nrPDB 49 1e-06 1WU2-A nrPDB 32 0.25 1DJ2-A nrPDB 30 0.70 2WGW-B nrPDB 29 1.5 4V99-AA nrPDB 29 1.5 2Q2I-A nrPDB 28 3.5 2Q2H-A nrPDB 28 3.5 6FCX-A nrPDB 27 3.8 >1DI7-A nrPDB Length = 195 Score = 394 bits (1012), Expect = e-110, Method: Compositional matrix adjust. Identities = 194/195 (99%), Positives = 194/195 (99%) Query: 1 MNTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQTLCE 60 M TLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQTLCE Sbjct: 1 MATLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQTLCE 60 Query: 61 LVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTAILSRQV 120 LVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTAILSRQV Sbjct: 61 LVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTAILSRQV 120 Query: 121 GVIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFASVPYCIQLLEGPYVETAPEV 180 GVIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFASVPYCIQLLEGPYVETAPEV Sbjct: 121 GVIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFASVPYCIQLLEGPYVETAPEV 180 Query: 181 VAAFRPKSARRDVSE 195 VAAFRPKSARRDVSE Sbjct: 181 VAAFRPKSARRDVSE 195 >3MCI-A nrPDB Length = 178 Score = 199 bits (507), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 100/183 (54%), Positives = 128/183 (69%), Gaps = 12/183 (6%) Query: 6 IGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQTLCELVDEM 65 IG+V+ISDRAS G+Y+D A+ ++L + TPFE+E R+IPDE+ +IE+TL EL DE Sbjct: 8 IGVVTISDRASKGIYEDISGKAIIDYLKDVIITPFEVEYRVIPDERDLIEKTLIELADEK 67 Query: 66 SCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTAILSRQVGVIRK 125 C L+LTTGGTGPA RDVTP+AT AV ++ +PGFGE MRQ+SL VPTAILSRQ IR Sbjct: 68 GCSLILTTGGTGPAPRDVTPEATEAVCEKMLPGFGELMRQVSLKQVPTAILSRQTAGIRG 127 Query: 126 QALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFASVPYCIQLLEGPYVETAPEVVAAFR 185 LI+NLPG+P+SIK L+ V ++PYCI L+ G Y++T P V AFR Sbjct: 128 SCLIVNLPGKPQSIKVCLDAV------------MPAIPYCIDLIGGAYIDTDPNKVKAFR 175 Query: 186 PKS 188 PK Sbjct: 176 PKK 178 >2F7Y-A nrPDB Length = 177 Score = 199 bits (506), Expect = 7e-52, Method: Compositional matrix adjust. Identities = 99/188 (52%), Positives = 132/188 (70%), Gaps = 12/188 (6%) Query: 1 MNTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQTLCE 60 M+ +IG+V++SDRAS+G+Y+D A+ + L LT+ +E ++IPDEQ +IE TL + Sbjct: 1 MSKAKIGIVTVSDRASAGIYEDISGKAIIDTLNDYLTSEWEPIYQVIPDEQDVIETTLIK 60 Query: 61 LVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTAILSRQV 120 + DE C L++TTGGTGPA+RDVTP+AT AV DR MPGFGE MR SL FVPTAILSRQ Sbjct: 61 MADEQDCCLIVTTGGTGPAKRDVTPEATEAVCDRMMPGFGELMRAESLKFVPTAILSRQT 120 Query: 121 GVIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFASVPYCIQLLEGPYVETAPEV 180 +R +LI+NLPG+PKSI+E L+ V F ++PYCI L+EGPY+E V Sbjct: 121 AGLRGDSLIVNLPGKPKSIRECLDAV------------FPAIPYCIDLMEGPYLECNEAV 168 Query: 181 VAAFRPKS 188 + FRPK+ Sbjct: 169 IKPFRPKA 176 >4XCW-A nrPDB Length = 178 Score = 187 bits (476), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 91/187 (48%), Positives = 125/187 (66%), Gaps = 12/187 (6%) Query: 1 MNTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQTLCE 60 M T+ IG++S SDRAS GVY+D A++E L+ L P E ++ DE+ +IE++L + Sbjct: 3 MQTIHIGVLSASDRASKGVYEDLSGKAIQEVLSEYLLNPLEFHYEIVADERDLIEKSLIK 62 Query: 61 LVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTAILSRQV 120 + DE C LV+TTGGTGPA RD+TP+AT V + +PGFGE MR SL +VPTAILSRQ Sbjct: 63 MCDEYQCDLVVTTGGTGPALRDITPEATKKVCQKMLPGFGELMRMTSLKYVPTAILSRQS 122 Query: 121 GVIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFASVPYCIQLLEGPYVETAPEV 180 IR ++LI+NLPG+PKSI+E LE V F ++PYC+ L+ G Y++ + Sbjct: 123 AGIRNKSLIINLPGKPKSIRECLEAV------------FPAIPYCVDLILGNYMQVNEKN 170 Query: 181 VAAFRPK 187 + AFRPK Sbjct: 171 IQAFRPK 177 >4NWO-A nrPDB Length = 177 Score = 179 bits (455), Expect = 5e-46, Method: Compositional matrix adjust. Identities = 94/188 (50%), Positives = 124/188 (65%), Gaps = 12/188 (6%) Query: 1 MNTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQTLCE 60 M+ +IG+V++SDRAS+G+ D A+ L LT+ +E ++IPDEQ +IE TL + Sbjct: 1 MSKAKIGIVTVSDRASAGITADISGKAIILALNLYLTSEWEPIYQVIPDEQDVIETTLIK 60 Query: 61 LVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTAILSRQV 120 + DE C L++TTGGTGPA+RDVTP+AT AV DR MPGFGE MR SL VPTAILSRQ Sbjct: 61 MADEQDCCLIVTTGGTGPAKRDVTPEATEAVCDRMMPGFGELMRAESLKEVPTAILSRQT 120 Query: 121 GVIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFASVPYCIQLLEGPYVETAPEV 180 +R +LI+NLPG P SI + L V F ++PYCI L+EGPY+E + Sbjct: 121 AGLRGDSLIVNLPGDPASISDCLLAV------------FPAIPYCIDLMEGPYLECNEAM 168 Query: 181 VAAFRPKS 188 + FRPK+ Sbjct: 169 IKPFRPKA 176 >2IS8-A nrPDB Length = 164 Score = 109 bits (273), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 63/144 (43%), Positives = 84/144 (58%), Gaps = 4/144 (2%) Query: 4 LRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELET-RLIPDEQAIIEQTLCELV 62 R+G++++SD+ G QD A+ E L PFE+ L+PDE +I++ L Sbjct: 2 FRVGILTVSDKGFRGERQDTTHLAIREVLAGG---PFEVAAYELVPDEPPMIKKVLRLWA 58 Query: 63 DEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTAILSRQVGV 122 D L+LT GGTG A RD TP+AT + DRE+PG E MR + L P A LSR V Sbjct: 59 DREGLDLILTNGGTGLAPRDRTPEATRELLDREVPGLAELMRLVGLRKTPMAALSRGVAG 118 Query: 123 IRKQALILNLPGQPKSIKETLEGV 146 +R + LILNLPG PK +E+LE V Sbjct: 119 VRGRTLILNLPGSPKGARESLEAV 142 >1IHC-A nrPDB Length = 188 Score = 92.8 bits (229), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 60/175 (34%), Positives = 94/175 (53%), Gaps = 13/175 (7%) Query: 2 NTLRIGLVSISDRASSGVYQDKGIPALEEWLTS-ALTTPFELETRLIPDEQAIIEQTLCE 60 + +R+G++++SD + +D+ L++ + +L +++PDE I++TL + Sbjct: 13 HQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVPDEIEEIKETLID 72 Query: 61 LVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTAILSRQV 120 DE +L+LTTGGTG A RDVTP+AT V +RE PG M SL+ P +LSR V Sbjct: 73 WCDEKELNLILTTGGTGFAPRDVTPEATKEVIEREAPGMALAMLMGSLNVTPLGMLSRPV 132 Query: 121 GVIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFASVPYCIQLLEGPYVE 175 IR + LI+NLPG K +E + I ++P+ I LL V+ Sbjct: 133 CGIRGKTLIINLPGSKKGSQECFQ------------FILPALPHAIDLLRDAIVK 175 >1O8Q-A nrPDB Length = 167 Score = 85.1 bits (209), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 52/145 (35%), Positives = 78/145 (53%), Gaps = 3/145 (2%) Query: 5 RIGLVSISDRASSGVYQDKGIPALEEWLTSA---LTTPFELETRLIPDEQAIIEQTLCEL 61 ++ ++++SD S+G D+ P + S+ L + T ++PDE I+ L + Sbjct: 7 KVAILTVSDTVSAGAGPDRSGPRAVSVVDSSSEKLGGAKVVATAVVPDEVERIKDILQKW 66 Query: 62 VDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTAILSRQVG 121 D L+LT GGTG RDVTP+AT V +RE PG M Q +L P A+LSR Sbjct: 67 SDVDEMDLILTLGGTGFTPRDVTPEATKKVIERETPGLLFVMMQEALKITPFAMLSRSAA 126 Query: 122 VIRKQALILNLPGQPKSIKETLEGV 146 IR LI+N+PG P ++ E +E + Sbjct: 127 GIRGSTLIINMPGNPNAVAECMEAL 151 >4LHB-A nrPDB Length = 186 Score = 68.6 bits (166), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 48/160 (30%), Positives = 87/160 (54%), Gaps = 10/160 (6%) Query: 2 NTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQTLCEL 61 T + G++++SD+ + G +DK P + E L+ + +++PD++ + L E Sbjct: 29 KTFKFGVITVSDKGAKGEREDKSGPLIIEELSKLGEHVY---YKIVPDDKIEVLIALFEA 85 Query: 62 VDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTA-ILSR-Q 119 + + +V+TTGGTG RRD+T ++ + D+E+ FGE R S V A +L+R Sbjct: 86 I-KSGADVVVTTGGTGITRRDITIESIKPLFDKELS-FGEVFRAKSYEEVGYATVLTRAT 143 Query: 120 VGVIRKQ---ALILNLPGQPKSIKETLEGVKDAEGNVVVH 156 G+IR Q ++ +LPG ++K LE +K +++ H Sbjct: 144 AGIIRGQERIVVVFSLPGSVNAVKTGLEIIKSEVFHILKH 183 >1Y5E-A nrPDB Length = 169 Score = 64.7 bits (156), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 45/141 (31%), Positives = 74/141 (52%), Gaps = 10/141 (7%) Query: 4 LRIGLVSISDRASSGVYQDKGIPALEEWLTSA--LTTPFELETRLIPDEQAIIEQTLCEL 61 +R +V+ISD + DK L E L A T +E+ + D++ I+Q + Sbjct: 14 VRCKIVTISDTRTE--ETDKSGQLLHELLKEAGHKVTSYEI----VKDDKESIQQAVLAG 67 Query: 62 VDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISL--HFVPTAILSRQ 119 + +VLT GGTG +RDVT +A A+ D+E+ GFGE R IS +A+LSR Sbjct: 68 YHKEDVDVVLTNGGTGITKRDVTIEAVSALLDKEIVGFGELFRMISYLEDIGSSAMLSRA 127 Query: 120 VGVIRKQALILNLPGQPKSIK 140 +G + ++ ++PG +++ Sbjct: 128 IGGTIGRKVVFSMPGSSGAVR 148 >1R2K-B nrPDB Length = 169 Score = 57.4 bits (137), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 32/102 (31%), Positives = 51/102 (50%), Gaps = 1/102 (0%) Query: 46 LIPDEQAIIEQTLCELVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQ 105 ++ + + I + + +VL TGGTG D P+A L + DRE+ GFGE R Sbjct: 48 IVKENRYAIRAQVSAWIASDDVQVVLITGGTGLTEGDQAPEALLPLFDREVEGFGEVFRM 107 Query: 106 ISLHFVPTAIL-SRQVGVIRKQALILNLPGQPKSIKETLEGV 146 +S + T+ L SR V + + LI +PG K+ + E + Sbjct: 108 LSFEEIGTSTLQSRAVAGVANKTLIFAMPGSTKACRTAWENI 149 >3IWT-A nrPDB Length = 178 Score = 49.3 bits (116), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 30/103 (29%), Positives = 56/103 (54%), Gaps = 5/103 (4%) Query: 46 LIPDEQAIIEQTLCELVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQ 105 L+PD++ I + + + ++++TGGTG + D+T + + DRE+ GF + R Sbjct: 61 LVPDDKIKILKAFTDALSIDEVDVIISTGGTGYSPTDITVETIRKLFDREIEGFSDVFRL 120 Query: 106 ISLH---FVPTAILSR-QVGVIRKQALILNLPGQPKSIKETLE 144 +S + A L++ G+I K+ + L LPG P ++K L+ Sbjct: 121 VSFNDPEVKAAAYLTKASAGIIGKKIVYL-LPGSPDAVKLALK 162 >1WU2-A nrPDB Length = 396 Score = 31.6 bits (70), Expect = 0.25, Method: Compositional matrix adjust. Identities = 14/37 (37%), Positives = 26/37 (70%), Gaps = 2/37 (5%) Query: 46 LIPDEQAIIEQTLCELVDEMSCHLVLTTGGTGPARRD 82 ++PD+++II++TL + +E C +VL TGG+ +D Sbjct: 232 VLPDDESIIKETLEKAKNE--CDIVLITGGSAFGDKD 266 >1DJ2-A nrPDB Length = 443 Score = 30.0 bits (66), Expect = 0.70, Method: Compositional matrix adjust. Identities = 11/41 (26%), Positives = 23/41 (56%) Query: 99 FGEQMRQISLHFVPTAILSRQVGVIRKQALILNLPGQPKSI 139 + + ++ +LH VP+ IL+ + ++++LPG K I Sbjct: 62 YNSEGKKFALHLVPSGILNEDTTCVIGNGVVVHLPGLFKEI 102 >2WGW-B nrPDB Length = 248 Score = 28.9 bits (63), Expect = 1.5, Method: Compositional matrix adjust. Identities = 9/31 (29%), Positives = 20/31 (64%) Query: 111 VPTAILSRQVGVIRKQALILNLPGQPKSIKE 141 +P AI+ + GVI+ + + G+P+++K+ Sbjct: 53 IPNAIIGLETGVIKNEHQVFKWDGKPRAMKQ 83 >4V99-AA nrPDB Length = 242 Score = 28.9 bits (63), Expect = 1.5, Method: Compositional matrix adjust. Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 12/78 (15%) Query: 30 EWLTSA-LTTPFELETRLIPDEQAIIEQTLCELVDEMSCHLV-----------LTTGGTG 77 EW+ S TTP L R P+ +TL +L+D S LV + T G Sbjct: 121 EWIPSCPTTTPGNLVLRFYPNYSTETPKTLTDLMDSESLVLVPSLSGKTYRPKIETRGNP 180 Query: 78 PARRDVTPDATLAVADRE 95 P R++ A A++D + Sbjct: 181 PELRNIDATAFSALSDED 198 >2Q2I-A nrPDB Length = 116 Score = 27.7 bits (60), Expect = 3.5, Method: Compositional matrix adjust. Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 15/72 (20%) Query: 98 GFGEQMRQISLHFVPTAILSRQV-GVIRKQALILNLPGQPKSI----KETLE-GVKDAEG 151 G + QI++H+ P +++ RQV GV+ N P P+ I E L G DA G Sbjct: 48 GIKKSSAQITVHYTPESLVGRQVLGVV-------NFP--PRQIGPFRSEVLTLGFADANG 98 Query: 152 NVVVHGIFASVP 163 ++V+ + VP Sbjct: 99 DIVLAAVERPVP 110 >2Q2H-A nrPDB Length = 131 Score = 27.7 bits (60), Expect = 3.5, Method: Compositional matrix adjust. Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 15/72 (20%) Query: 98 GFGEQMRQISLHFVPTAILSRQV-GVIRKQALILNLPGQPKSI----KETLE-GVKDAEG 151 G + QI++H+ P +++ RQV GV+ N P P+ I E L G DA G Sbjct: 63 GIKKSSAQITVHYTPESLVGRQVLGVV-------NFP--PRQIGPFRSEVLTLGFADANG 113 Query: 152 NVVVHGIFASVP 163 ++V+ + VP Sbjct: 114 DIVLAAVERPVP 125 >6FCX-A nrPDB Length = 615 Score = 27.3 bits (59), Expect = 3.8, Method: Compositional matrix adjust. Identities = 12/34 (35%), Positives = 21/34 (61%) Query: 136 PKSIKETLEGVKDAEGNVVVHGIFASVPYCIQLL 169 P+ IK+ +E +KD + + +GI +V C +LL Sbjct: 241 PQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELL 274 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1DI7-A nrPDB 285 1e-77 2F7Y-A nrPDB 264 2e-71 4XCW-A nrPDB 262 8e-71 4NWO-A nrPDB 250 3e-67 3MCI-A nrPDB 245 1e-65 1IHC-A nrPDB 206 5e-54 2IS8-A nrPDB 189 6e-49 1O8Q-A nrPDB 175 1e-44 4LHB-A nrPDB 163 5e-41 1Y5E-A nrPDB 156 5e-39 1R2K-B nrPDB 153 5e-38 3IWT-A nrPDB 132 1e-31 Sequences not found previously or not previously below threshold: 5G2R-A nrPDB 43 7e-05 2FU3-A nrPDB 40 4e-04 1XI8-A nrPDB 40 5e-04 1WU2-A nrPDB 38 0.002 1UZ5-A nrPDB 34 0.030 4CT9-A nrPDB 30 0.59 4ZCH-A nrPDB 29 1.9 3DKP-A nrPDB 28 3.5 2Q8N-A nrPDB 27 4.0 >1DI7-A nrPDB Length = 195 Score = 285 bits (728), Expect = 1e-77, Method: Composition-based stats. Identities = 194/195 (99%), Positives = 194/195 (99%) Query: 1 MNTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQTLCE 60 M TLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQTLCE Sbjct: 1 MATLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQTLCE 60 Query: 61 LVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTAILSRQV 120 LVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTAILSRQV Sbjct: 61 LVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTAILSRQV 120 Query: 121 GVIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFASVPYCIQLLEGPYVETAPEV 180 GVIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFASVPYCIQLLEGPYVETAPEV Sbjct: 121 GVIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFASVPYCIQLLEGPYVETAPEV 180 Query: 181 VAAFRPKSARRDVSE 195 VAAFRPKSARRDVSE Sbjct: 181 VAAFRPKSARRDVSE 195 >2F7Y-A nrPDB Length = 177 Score = 264 bits (674), Expect = 2e-71, Method: Composition-based stats. Identities = 99/188 (52%), Positives = 132/188 (70%), Gaps = 12/188 (6%) Query: 1 MNTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQTLCE 60 M+ +IG+V++SDRAS+G+Y+D A+ + L LT+ +E ++IPDEQ +IE TL + Sbjct: 1 MSKAKIGIVTVSDRASAGIYEDISGKAIIDTLNDYLTSEWEPIYQVIPDEQDVIETTLIK 60 Query: 61 LVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTAILSRQV 120 + DE C L++TTGGTGPA+RDVTP+AT AV DR MPGFGE MR SL FVPTAILSRQ Sbjct: 61 MADEQDCCLIVTTGGTGPAKRDVTPEATEAVCDRMMPGFGELMRAESLKFVPTAILSRQT 120 Query: 121 GVIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFASVPYCIQLLEGPYVETAPEV 180 +R +LI+NLPG+PKSI+E L+ V F ++PYCI L+EGPY+E V Sbjct: 121 AGLRGDSLIVNLPGKPKSIRECLDAV------------FPAIPYCIDLMEGPYLECNEAV 168 Query: 181 VAAFRPKS 188 + FRPK+ Sbjct: 169 IKPFRPKA 176 >4XCW-A nrPDB Length = 178 Score = 262 bits (669), Expect = 8e-71, Method: Composition-based stats. Identities = 91/188 (48%), Positives = 125/188 (66%), Gaps = 12/188 (6%) Query: 1 MNTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQTLCE 60 M T+ IG++S SDRAS GVY+D A++E L+ L P E ++ DE+ +IE++L + Sbjct: 3 MQTIHIGVLSASDRASKGVYEDLSGKAIQEVLSEYLLNPLEFHYEIVADERDLIEKSLIK 62 Query: 61 LVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTAILSRQV 120 + DE C LV+TTGGTGPA RD+TP+AT V + +PGFGE MR SL +VPTAILSRQ Sbjct: 63 MCDEYQCDLVVTTGGTGPALRDITPEATKKVCQKMLPGFGELMRMTSLKYVPTAILSRQS 122 Query: 121 GVIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFASVPYCIQLLEGPYVETAPEV 180 IR ++LI+NLPG+PKSI+E LE V F ++PYC+ L+ G Y++ + Sbjct: 123 AGIRNKSLIINLPGKPKSIRECLEAV------------FPAIPYCVDLILGNYMQVNEKN 170 Query: 181 VAAFRPKS 188 + AFRPK Sbjct: 171 IQAFRPKQ 178 >4NWO-A nrPDB Length = 177 Score = 250 bits (638), Expect = 3e-67, Method: Composition-based stats. Identities = 94/188 (50%), Positives = 124/188 (65%), Gaps = 12/188 (6%) Query: 1 MNTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQTLCE 60 M+ +IG+V++SDRAS+G+ D A+ L LT+ +E ++IPDEQ +IE TL + Sbjct: 1 MSKAKIGIVTVSDRASAGITADISGKAIILALNLYLTSEWEPIYQVIPDEQDVIETTLIK 60 Query: 61 LVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTAILSRQV 120 + DE C L++TTGGTGPA+RDVTP+AT AV DR MPGFGE MR SL VPTAILSRQ Sbjct: 61 MADEQDCCLIVTTGGTGPAKRDVTPEATEAVCDRMMPGFGELMRAESLKEVPTAILSRQT 120 Query: 121 GVIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFASVPYCIQLLEGPYVETAPEV 180 +R +LI+NLPG P SI + L V F ++PYCI L+EGPY+E + Sbjct: 121 AGLRGDSLIVNLPGDPASISDCLLAV------------FPAIPYCIDLMEGPYLECNEAM 168 Query: 181 VAAFRPKS 188 + FRPK+ Sbjct: 169 IKPFRPKA 176 >3MCI-A nrPDB Length = 178 Score = 245 bits (624), Expect = 1e-65, Method: Composition-based stats. Identities = 100/187 (53%), Positives = 128/187 (68%), Gaps = 12/187 (6%) Query: 2 NTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQTLCEL 61 IG+V+ISDRAS G+Y+D A+ ++L + TPFE+E R+IPDE+ +IE+TL EL Sbjct: 4 KKAVIGVVTISDRASKGIYEDISGKAIIDYLKDVIITPFEVEYRVIPDERDLIEKTLIEL 63 Query: 62 VDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTAILSRQVG 121 DE C L+LTTGGTGPA RDVTP+AT AV ++ +PGFGE MRQ+SL VPTAILSRQ Sbjct: 64 ADEKGCSLILTTGGTGPAPRDVTPEATEAVCEKMLPGFGELMRQVSLKQVPTAILSRQTA 123 Query: 122 VIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFASVPYCIQLLEGPYVETAPEVV 181 IR LI+NLPG+P+SIK L+ V ++PYCI L+ G Y++T P V Sbjct: 124 GIRGSCLIVNLPGKPQSIKVCLDAV------------MPAIPYCIDLIGGAYIDTDPNKV 171 Query: 182 AAFRPKS 188 AFRPK Sbjct: 172 KAFRPKK 178 >1IHC-A nrPDB Length = 188 Score = 206 bits (524), Expect = 5e-54, Method: Composition-based stats. Identities = 60/178 (33%), Positives = 94/178 (52%), Gaps = 13/178 (7%) Query: 2 NTLRIGLVSISDRASSGVYQDKGIPALEEWLTS-ALTTPFELETRLIPDEQAIIEQTLCE 60 + +R+G++++SD + +D+ L++ + +L +++PDE I++TL + Sbjct: 13 HQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVPDEIEEIKETLID 72 Query: 61 LVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTAILSRQV 120 DE +L+LTTGGTG A RDVTP+AT V +RE PG M SL+ P +LSR V Sbjct: 73 WCDEKELNLILTTGGTGFAPRDVTPEATKEVIEREAPGMALAMLMGSLNVTPLGMLSRPV 132 Query: 121 GVIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFASVPYCIQLLEGPYVETAP 178 IR + LI+NLPG K +E + I ++P+ I LL V+ Sbjct: 133 CGIRGKTLIINLPGSKKGSQECFQ------------FILPALPHAIDLLRDAIVKVKE 178 >2IS8-A nrPDB Length = 164 Score = 189 bits (480), Expect = 6e-49, Method: Composition-based stats. Identities = 66/169 (39%), Positives = 91/169 (53%), Gaps = 16/169 (9%) Query: 4 LRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELE-TRLIPDEQAIIEQTLCELV 62 R+G++++SD+ G QD A+ E L PFE+ L+PDE +I++ L Sbjct: 2 FRVGILTVSDKGFRGERQDTTHLAIREVLAG---GPFEVAAYELVPDEPPMIKKVLRLWA 58 Query: 63 DEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTAILSRQVGV 122 D L+LT GGTG A RD TP+AT + DRE+PG E MR + L P A LSR V Sbjct: 59 DREGLDLILTNGGTGLAPRDRTPEATRELLDREVPGLAELMRLVGLRKTPMAALSRGVAG 118 Query: 123 IRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFASVPYCIQLLEG 171 +R + LILNLPG PK +E+LE V +P+ + L+ G Sbjct: 119 VRGRTLILNLPGSPKGARESLEAV------------LPVLPHALSLVTG 155 >1O8Q-A nrPDB Length = 167 Score = 175 bits (443), Expect = 1e-44, Method: Composition-based stats. Identities = 53/157 (33%), Positives = 81/157 (51%), Gaps = 3/157 (1%) Query: 3 TLRIGLVSISDRASSGVYQDKGIPALEEWLTSA---LTTPFELETRLIPDEQAIIEQTLC 59 ++ ++++SD S+G D+ P + S+ L + T ++PDE I+ L Sbjct: 5 EYKVAILTVSDTVSAGAGPDRSGPRAVSVVDSSSEKLGGAKVVATAVVPDEVERIKDILQ 64 Query: 60 ELVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTAILSRQ 119 + D L+LT GGTG RDVTP+AT V +RE PG M Q +L P A+LSR Sbjct: 65 KWSDVDEMDLILTLGGTGFTPRDVTPEATKKVIERETPGLLFVMMQEALKITPFAMLSRS 124 Query: 120 VGVIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVH 156 IR LI+N+PG P ++ E +E + A + + Sbjct: 125 AAGIRGSTLIINMPGNPNAVAECMEALLPALKHALKQ 161 >4LHB-A nrPDB Length = 186 Score = 163 bits (412), Expect = 5e-41, Method: Composition-based stats. Identities = 47/160 (29%), Positives = 85/160 (53%), Gaps = 10/160 (6%) Query: 2 NTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQTLCEL 61 T + G++++SD+ + G +DK P + E L+ + +++PD++ + L E Sbjct: 29 KTFKFGVITVSDKGAKGEREDKSGPLIIEELSKLGEHVY---YKIVPDDKIEVLIALFEA 85 Query: 62 VDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTA-ILSRQV 120 + + +V+TTGGTG RRD+T ++ + D+E+ FGE R S V A +L+R Sbjct: 86 I-KSGADVVVTTGGTGITRRDITIESIKPLFDKELS-FGEVFRAKSYEEVGYATVLTRAT 143 Query: 121 GV-IRKQ---ALILNLPGQPKSIKETLEGVKDAEGNVVVH 156 IR Q ++ +LPG ++K LE +K +++ H Sbjct: 144 AGIIRGQERIVVVFSLPGSVNAVKTGLEIIKSEVFHILKH 183 >1Y5E-A nrPDB Length = 169 Score = 156 bits (395), Expect = 5e-39, Method: Composition-based stats. Identities = 44/155 (28%), Positives = 77/155 (49%), Gaps = 7/155 (4%) Query: 2 NTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQTLCEL 61 +R +V+ISD + DK L E L A ++ D++ I+Q + Sbjct: 12 KEVRCKIVTISDTRT--EETDKSGQLLHELLKEA--GHKVTSYEIVKDDKESIQQAVLAG 67 Query: 62 VDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISL--HFVPTAILSRQ 119 + +VLT GGTG +RDVT +A A+ D+E+ GFGE R IS +A+LSR Sbjct: 68 YHKEDVDVVLTNGGTGITKRDVTIEAVSALLDKEIVGFGELFRMISYLEDIGSSAMLSRA 127 Query: 120 VGVIRKQALILNLPGQPKSIKETL-EGVKDAEGNV 153 +G + ++ ++PG +++ + + + G++ Sbjct: 128 IGGTIGRKVVFSMPGSSGAVRLAMNKLILPELGHI 162 >1R2K-B nrPDB Length = 169 Score = 153 bits (386), Expect = 5e-38, Method: Composition-based stats. Identities = 40/143 (27%), Positives = 67/143 (46%), Gaps = 5/143 (3%) Query: 5 RIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQTLCELVDE 64 RI ++++S+R G D L + A ++ ++ + + I + + Sbjct: 11 RIAILTVSNR--RGEEDDTSGHYLRDSAQEAGHH--VVDKAIVKENRYAIRAQVSAWIAS 66 Query: 65 MSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTAIL-SRQVGVI 123 +VL TGGTG D P+A L + DRE+ GFGE R +S + T+ L SR V + Sbjct: 67 DDVQVVLITGGTGLTEGDQAPEALLPLFDREVEGFGEVFRMLSFEEIGTSTLQSRAVAGV 126 Query: 124 RKQALILNLPGQPKSIKETLEGV 146 + LI +PG K+ + E + Sbjct: 127 ANKTLIFAMPGSTKACRTAWENI 149 >3IWT-A nrPDB Length = 178 Score = 132 bits (331), Expect = 1e-31, Method: Composition-based stats. Identities = 35/162 (21%), Positives = 74/162 (45%), Gaps = 11/162 (6%) Query: 2 NTLRIGLVSISDRASSGVYQ-----DKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQ 56 +L +++IS + + D+ +++ L + L+PD++ I + Sbjct: 14 KSLNFYVITISTSRYEKLLKKEPIVDESGDIIKQLLIE--NGHKIIGYSLVPDDKIKILK 71 Query: 57 TLCELVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLH---FVPT 113 + + ++++TGGTG + D+T + + DRE+ GF + R +S + Sbjct: 72 AFTDALSIDEVDVIISTGGTGYSPTDITVETIRKLFDREIEGFSDVFRLVSFNDPEVKAA 131 Query: 114 AILSRQVGVIRKQALILNLPGQPKSIKETL-EGVKDAEGNVV 154 A L++ I + ++ LPG P ++K L E + G++V Sbjct: 132 AYLTKASAGIIGKKIVYLLPGSPDAVKLALKELILPEVGHLV 173 >5G2R-A nrPDB Length = 471 Score = 43.2 bits (100), Expect = 7e-05, Method: Composition-based stats. Identities = 21/135 (15%), Positives = 48/135 (35%), Gaps = 8/135 (5%) Query: 46 LIPDEQAIIEQTLCELVDEMSCHLVLTTGGTGPARRDVTPDATLAVA-DREMPGFGEQMR 104 ++ D++ +E+ L E V ++LT+GG RD + ++ F + + Sbjct: 244 IVRDDRKELEKVLDEAVSS-GVDIILTSGGVSMGDRDF----VKPLLEEKGKVYFSKVLM 298 Query: 105 QISLHFVPTAILSRQVGVIRKQALI-LNLPGQPKSIKETLEGVKDAEGNVVVHGIFASVP 163 + I ++ + + ++ LPG P S + P Sbjct: 299 KPGKPLTFAEIRAKPTESMLGKTVLAFGLPGNPVSCLVCFNIFVVPTIRQLAGWTSPH-P 357 Query: 164 YCIQLLEGPYVETAP 178 ++L +++ P Sbjct: 358 LRVRLRLQEPIKSDP 372 >2FU3-A nrPDB Length = 419 Score = 40.5 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 21/101 (20%), Positives = 39/101 (38%), Gaps = 15/101 (14%) Query: 46 LIPDEQAIIEQTLCELVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPG---FGEQ 102 ++ D + L E + +++T+GG +D V D ++ FG Sbjct: 229 IVGDNPDDLLNALNEGISR--ADVIITSGGVSMGEKDY----LKQVLDIDLHAQIHFGRV 282 Query: 103 MRQISLHFVPTAILSRQVGVIRKQALILNLPGQP-KSIKET 142 + L PT + + +RK +I LPG P ++ Sbjct: 283 FMKPGL---PTTFATLDIDGVRK--IIFALPGNPVSAVVTC 318 >1XI8-A nrPDB Length = 403 Score = 40.5 bits (93), Expect = 5e-04, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 25/66 (37%), Gaps = 4/66 (6%) Query: 17 SGVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQTLCELVDEMSCHLVLTTGGT 76 G D L + P + ++PD + +I L + + C LVL TGG+ Sbjct: 212 KGKIVDTNSIMLSALVERYFGEP--ILYGVVPDNEDLIRSALEKA--KRECDLVLITGGS 267 Query: 77 GPARRD 82 D Sbjct: 268 AFGDMD 273 >1WU2-A nrPDB Length = 396 Score = 38.2 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 34/72 (47%), Gaps = 5/72 (6%) Query: 12 SDRASS-GVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQTLCELVDEMSCHLV 70 S+ G + L+ + P + ++PD+++II++TL + + C +V Sbjct: 199 SEEGFKEGKIVETNSIMLQGLVEKFFGEP--ILYGVLPDDESIIKETLEKA--KNECDIV 254 Query: 71 LTTGGTGPARRD 82 L TGG+ +D Sbjct: 255 LITGGSAFGDKD 266 >1UZ5-A nrPDB Length = 402 Score = 34.3 bits (77), Expect = 0.030, Method: Composition-based stats. Identities = 24/122 (19%), Positives = 47/122 (38%), Gaps = 16/122 (13%) Query: 18 GVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQTLCELVDEMSCHLVLTTGGTG 77 G D AL + + + + D++ ++ + + V+ +V+ +GG Sbjct: 202 GQIYDINGRALCDAINELGGEG--IFMGVARDDKESLKALIEKAVNVG--DVVVISGGAS 257 Query: 78 PARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTAILSRQVGVIRKQALILNLPGQPK 137 +D+T + + ++ G Q PT I GVI+ + + LPG P Sbjct: 258 GGTKDLTASVIEELGEVKVHGIAIQ------PGKPTII-----GVIKGKP-VFGLPGYPT 305 Query: 138 SI 139 S Sbjct: 306 SC 307 >4CT9-A nrPDB Length = 394 Score = 30.1 bits (66), Expect = 0.59, Method: Composition-based stats. Identities = 31/149 (20%), Positives = 50/149 (33%), Gaps = 35/149 (23%) Query: 47 IPDEQAIIEQTLCELVDEMSCHLVLTTGGTGPARRDVTPDAT-----LAV-ADREMPGFG 100 + DE A + + + E LV+ +GG GP DVT +A + D + G Sbjct: 43 VADEVAPLAREVEEAFAR--ARLVVLSGGLGPTPDDVTREAVALALGEPLELDEAVLGEI 100 Query: 101 EQM------------RQISLHFVPTAILSRQVGVI-------RKQALILNLPGQPKSIKE 141 E R+ ++ L G + L+L LPG P + Sbjct: 101 EAFFRARGRAMPEANRKQAMRIPSATWLKNPRGTAPGWWVRKGGKDLVL-LPGPPPEWRP 159 Query: 142 TLEGVKDAEGNVVVHGIFASVPYCIQLLE 170 + V G PY ++L+ Sbjct: 160 MWQEVLPRLG-------LPRRPYAERVLK 181 >4ZCH-A nrPDB Length = 438 Score = 28.6 bits (62), Expect = 1.9, Method: Composition-based stats. Identities = 9/48 (18%), Positives = 20/48 (41%) Query: 134 GQPKSIKETLEGVKDAEGNVVVHGIFASVPYCIQLLEGPYVETAPEVV 181 G ++ L+ + D+E + G + VP+ + G +E + Sbjct: 140 GSETVTQDCLQLIADSETPTIQKGSYTFVPWLLSFKRGSALEEKENKI 187 >3DKP-A nrPDB Length = 245 Score = 27.8 bits (60), Expect = 3.5, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 23/67 (34%), Gaps = 3/67 (4%) Query: 17 SGVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQTLCELVDEMSCHLVLTTGGT 76 + V K P + +TTP L L+ + I+ E + + G T Sbjct: 135 AAVAAKKFGPKSSKKFDILVTTPNRLIY-LLKQDPPGIDLASVEWLVVDESDKLFEDGKT 193 Query: 77 GPARRDV 83 G RD Sbjct: 194 GF--RDQ 198 >2Q8N-A nrPDB Length = 460 Score = 27.4 bits (59), Expect = 4.0, Method: Composition-based stats. Identities = 28/151 (18%), Positives = 61/151 (40%), Gaps = 11/151 (7%) Query: 17 SGVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIE--QTLCELVDEMSCHLVLTTG 74 SG D+ + ++EE +TSA+ E +++ I+ ++L + + +VL G Sbjct: 28 SGGLTDEDVKSVEEKVTSAVRNFVENTPDFAKLDRSWIDSVKSLEDWIINFDTVVVLGIG 87 Query: 75 GTGPAR----RDVTPDATLAVADREMPGFGEQMRQISLH-FVPTAILSRQVGVIRKQALI 129 G+G + P + E G+ ++ + +++L R I + + Sbjct: 88 GSGLGNLALHYSLRPLNWNEMTREERNGYARVFVVDNVDPDLMSSVLDR----IDPKTTL 143 Query: 130 LNLPGQPKSIKETLEGVKDAEGNVVVHGIFA 160 N+ + S E + A G + +G+ Sbjct: 144 FNVISKSGSTAEVMATYSIARGILEAYGLDP 174 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.129 0.327 Lambda K H 0.267 0.0395 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 6,625,320 Number of Sequences: 36641 Number of extensions: 227920 Number of successful extensions: 677 Number of sequences better than 10.0: 23 Number of HSP's better than 10.0 without gapping: 30 Number of HSP's successfully gapped in prelim test: 15 Number of HSP's that attempted gapping in prelim test: 621 Number of HSP's gapped (non-prelim): 47 length of query: 195 length of database: 10,336,785 effective HSP length: 92 effective length of query: 103 effective length of database: 6,965,813 effective search space: 717478739 effective search space used: 717478739 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 56 (26.2 bits)