BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P0AET8 (255 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1AHH-A nrPDB 521 e-148 2PNF-A nrPDB 147 5e-36 2UVD-A nrPDB 145 1e-35 4MOW-A nrPDB 145 2e-35 4NBT-A nrPDB 145 2e-35 2EW8-A nrPDB 142 1e-34 2C07-A nrPDB 140 7e-34 1GEE-A nrPDB 132 1e-31 2AE2-A nrPDB 132 2e-31 3OSU-A nrPDB 131 4e-31 5U9P-A nrPDB 130 4e-31 2ZAT-A nrPDB 130 5e-31 4AVY-A nrPDB 129 1e-30 3FTP-A nrPDB 127 3e-30 3O4R-A nrPDB 127 6e-30 4NBV-A nrPDB 127 7e-30 3WOH-A nrPDB 126 9e-30 5T5Q-A nrPDB 126 1e-29 2CDH-G nrPDB 125 2e-29 4JRO-A nrPDB 125 2e-29 5OJG-A nrPDB 125 2e-29 4RZH-A nrPDB 123 8e-29 3RSH-A nrPDB 123 9e-29 3UF0-A nrPDB 122 1e-28 2HQ1-A nrPDB 122 1e-28 1AE1-A nrPDB 121 2e-28 4Z9Y-A nrPDB 121 4e-28 4IIN-A nrPDB 120 4e-28 3OIC-A nrPDB 120 4e-28 1DOH-A nrPDB 120 5e-28 1CYD-A nrPDB 118 2e-27 6CI9-A nrPDB 117 5e-27 3WYE-A nrPDB 117 6e-27 3R3S-A nrPDB 116 7e-27 4M8S-A nrPDB 115 2e-26 4DMM-A nrPDB 115 2e-26 3RWB-A nrPDB 115 2e-26 1GEG-A nrPDB 115 2e-26 4BO1-A nrPDB 115 2e-26 1Q7C-A nrPDB 115 3e-26 3U5T-A nrPDB 114 3e-26 4FC7-A nrPDB 114 5e-26 1O5I-A nrPDB 112 1e-25 6NRP-A nrPDB 111 3e-25 5YSS-A nrPDB 111 4e-25 1K2W-A nrPDB 109 1e-24 4K6F-A nrPDB 109 1e-24 4TRR-A nrPDB 108 3e-24 4E6P-A nrPDB 107 3e-24 3LYL-A nrPDB 107 4e-24 3EMK-A nrPDB 107 5e-24 3V2G-A nrPDB 107 6e-24 5CDY-A nrPDB 106 9e-24 5ITV-A nrPDB 106 9e-24 4HP8-A nrPDB 106 9e-24 4KMS-A nrPDB 106 1e-23 5JS6-A nrPDB 105 2e-23 3AUT-A nrPDB 105 2e-23 1HXH-A nrPDB 105 3e-23 2CFC-A nrPDB 104 5e-23 4RZI-B nrPDB 103 6e-23 3V2H-A nrPDB 103 7e-23 3F9I-A nrPDB 103 7e-23 3WTC-A nrPDB 103 7e-23 3T7C-A nrPDB 102 1e-22 1YXM-A nrPDB 102 1e-22 4DBZ-A nrPDB 102 2e-22 3GRP-A nrPDB 101 2e-22 3D3W-A nrPDB 101 3e-22 5O3Z-A nrPDB 101 4e-22 3UN1-A nrPDB 101 4e-22 5B1Y-A nrPDB 100 4e-22 3OEC-A nrPDB 100 5e-22 2HSD-A nrPDB 100 7e-22 5VT6-A nrPDB 99 2e-21 3EZL-A nrPDB 99 2e-21 5JY1-A nrPDB 99 3e-21 4CQL-A nrPDB 98 3e-21 5IZ4-A nrPDB 98 4e-21 2Q2Q-A nrPDB 98 4e-21 3VZS-A nrPDB 98 4e-21 2FWM-X nrPDB 97 7e-21 3W8F-A nrPDB 97 9e-21 4IS3-A nrPDB 97 1e-20 2YW9-A nrPDB 96 1e-20 2NM0-A nrPDB 96 1e-20 1X1T-A nrPDB 95 2e-20 4CR6-A nrPDB 95 2e-20 3OML-A nrPDB 95 3e-20 1UZM-A nrPDB 94 4e-20 1H5Q-A nrPDB 94 6e-20 3V8B-A nrPDB 92 2e-19 2PH3-A nrPDB 92 3e-19 3U4C-A nrPDB 92 3e-19 4EGF-A nrPDB 91 7e-19 2P91-A nrPDB 90 8e-19 3GDF-A nrPDB 90 1e-18 1NFF-A nrPDB 90 1e-18 3ZV3-A nrPDB 89 2e-18 2BGM-A nrPDB 87 5e-18 4RGB-A nrPDB 87 7e-18 5EJ2-A nrPDB 87 7e-18 3A28-C nrPDB 87 8e-18 1W73-A nrPDB 87 1e-17 3PPI-A nrPDB 87 1e-17 4IIV-A nrPDB 87 1e-17 3UVE-A nrPDB 86 1e-17 2B4Q-A nrPDB 86 1e-17 4NR0-A nrPDB 84 4e-17 2AG5-A nrPDB 84 4e-17 4CQM-B nrPDB 84 6e-17 2O23-A nrPDB 84 9e-17 5OVL-A nrPDB 83 1e-16 5OVJ-A nrPDB 83 1e-16 1E3W-A nrPDB 83 1e-16 4GKB-A nrPDB 82 2e-16 4ZJU-A nrPDB 82 3e-16 2X9N-A nrPDB 80 1e-15 5CFZ-A nrPDB 79 3e-15 4JQC-A nrPDB 78 3e-15 1BDB-A nrPDB 78 3e-15 5TF4-A nrPDB 76 1e-14 3KZV-A nrPDB 75 2e-14 2GDZ-A nrPDB 75 4e-14 5YCX-A nrPDB 74 9e-14 5KOI-A nrPDB 71 6e-13 2PD3-A nrPDB 70 7e-13 3GRK-A nrPDB 70 9e-13 4DA9-A nrPDB 69 2e-12 1P33-A nrPDB 68 3e-12 5I9N-A nrPDB 68 4e-12 3RKU-A nrPDB 65 2e-11 3PXX-A nrPDB 65 3e-11 3K2E-A nrPDB 64 5e-11 3OIG-A nrPDB 64 5e-11 2O2S-A nrPDB 62 3e-10 4J3F-A nrPDB 61 5e-10 4M89-A nrPDB 60 8e-10 2DKN-A nrPDB 59 2e-09 1ENP-A nrPDB 59 2e-09 2BFA-A nrPDB 58 4e-09 2QHX-A nrPDB 58 4e-09 1FJH-A nrPDB 57 6e-09 5PGZ-A nrPDB 56 1e-08 4NK4-A nrPDB 56 2e-08 3DWF-A nrPDB 54 7e-08 2NWQ-A nrPDB 54 8e-08 4ALL-A nrPDB 54 9e-08 5L51-A nrPDB 53 1e-07 3O26-A nrPDB 52 2e-07 5LCX-A nrPDB 52 4e-07 3UCF-A nrPDB 51 4e-07 5ILO-A nrPDB 49 2e-06 2PTG-A nrPDB 46 2e-05 2HRB-A nrPDB 45 3e-05 3ORF-A nrPDB 45 4e-05 3U9L-A nrPDB 44 5e-05 4DRY-A nrPDB 44 5e-05 1N5D-A nrPDB 40 7e-04 4Z3K-A nrPDB 40 9e-04 3BHI-A nrPDB 40 0.001 4HWK-A nrPDB 40 0.001 3E9N-A nrPDB 39 0.001 1A27-A nrPDB 39 0.002 6CGE-A nrPDB 39 0.003 5WQO-A nrPDB 39 0.003 1OAA-A nrPDB 35 0.037 4HBG-A nrPDB 35 0.043 3F3S-A nrPDB 32 0.22 2O2Y-A nrPDB 31 0.44 6ACF-A nrPDB 31 0.57 2G2K-A nrPDB 30 0.75 2E9H-A nrPDB 30 0.87 3EWG-A nrPDB 30 1.4 3ENK-A nrPDB 30 1.5 6GAZ-AN nrPDB 29 1.7 3X2F-A nrPDB 29 1.7 1MG5-A nrPDB 29 1.8 3OND-A nrPDB 29 1.9 4LIS-A nrPDB 29 2.5 6DEB-A nrPDB 28 3.0 3J9M-AK nrPDB 28 3.4 3JD5-N nrPDB 28 3.5 5XU1-M nrPDB 28 3.5 6GUA-A nrPDB 28 5.6 2QCV-A nrPDB 27 5.9 3QKW-A nrPDB 27 6.5 1BW9-B nrPDB 27 8.7 >1AHH-A nrPDB Length = 255 Score = 521 bits (1341), Expect = e-148, Method: Compositional matrix adjust. Identities = 255/255 (100%), Positives = 255/255 (100%) Query: 1 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG 60 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG Sbjct: 1 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG 60 Query: 61 QAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVF 120 QAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVF Sbjct: 61 QAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVF 120 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK Sbjct: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 Query: 181 NIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVS 240 NIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVS Sbjct: 181 NIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVS 240 Query: 241 GQILTVSGGGVQELN 255 GQILTVSGGGVQELN Sbjct: 241 GQILTVSGGGVQELN 255 >2PNF-A nrPDB Length = 248 Score = 147 bits (371), Expect = 5e-36, Method: Compositional matrix adjust. Identities = 80/245 (32%), Positives = 147/245 (60%), Gaps = 3/245 (1%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEI-QQLGGQAFAC 65 ++L GK +++TG+ GIG+ IA A+AG++V+++ + + A V +EI + G +A Sbjct: 3 IKLQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGV 62 Query: 66 RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFH 124 ++ SE+ ++ + + + +DILVNNAG K F M + D+ ++N+ F Sbjct: 63 EMNLLSEESINKAFEEIYNLVDGIDILVNNAGITRDKLFLRMSLLDWEEVLKVNLTGTFL 122 Query: 125 LSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 ++Q +M K G I+ I+S+ N+ +Y+++KA +++A +L +N+ V Sbjct: 123 VTQNSLRKMIKQRWGRIVNISSVVGFTGNVGQVNYSTTKAGLIGFTKSLAKELAPRNVLV 182 Query: 185 NGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQIL 244 N +APG I TD + +V++ EI+QK + P+ R G P+++AN LFLCS AS+++G+++ Sbjct: 183 NAVAPGFIETD-MTAVLSEEIKQKYKEQIPLGRFGSPEEVANVVLFLCSELASYITGEVI 241 Query: 245 TVSGG 249 V+GG Sbjct: 242 HVNGG 246 >2UVD-A nrPDB Length = 246 Score = 145 bits (366), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 91/245 (37%), Positives = 133/245 (54%), Gaps = 3/245 (1%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDI-NADAANHVVDEIQQLGGQAFACRC 67 L GK A++TGA GIG+ IAI A GA+VVV+ N AN VVDEI++LG A A R Sbjct: 2 LKGKVALVTGASRGIGRAIAIDLAKQGANVVVNYAGNEQKANEVVDEIKKLGSDAIAVRA 61 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLS 126 D+ + ++++ + + G+VDILVNNAG M ++ N+ F + Sbjct: 62 DVANAEDVTNMVKQTVDVFGQVDILVNNAGVTKDNLLMRMKEEEWDTVINTNLKGVFLCT 121 Query: 127 QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNG 186 + V+ M + G I+ I S+ N +Y ++KA L + A +L +NI VN Sbjct: 122 KAVSRFMMRQRHGRIVNIASVVGVTGNPGQANYVAAKAGVIGLTKTSAKELASRNITVNA 181 Query: 187 IAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTV 246 IAPG I TD + V+ I+ +ML+ P + G+ QDIANA F S + +++GQ L V Sbjct: 182 IAPGFIATD-MTDVLDENIKAEMLKLIPAAQFGEAQDIANAVTFFASDQSKYITGQTLNV 240 Query: 247 SGGGV 251 GG V Sbjct: 241 DGGMV 245 >4MOW-A nrPDB Length = 256 Score = 145 bits (366), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 90/246 (36%), Positives = 138/246 (56%), Gaps = 6/246 (2%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADA-ANHVVDEIQQLGGQAFACR 66 +L GK AI+TGA GIG IA A GA+VVV+ ++ A A+ VV I + GG+A A Sbjct: 11 KLAGKVAIVTGASKGIGAAIAKALADEGAAVVVNYASSKAGADAVVSAITEAGGRAVAVG 70 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFHL 125 D++ + + D AI G++D+LVNN+G P + + +RR ++ NVF Sbjct: 71 GDVSKAADAQRIVDTAIETYGRLDVLVNNSGVYEFAPIEAITEEHYRRQFDTNVFGVLLT 130 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 +Q + + G I+ I+S+ Y+ +K A + +A +LG + IRVN Sbjct: 131 TQAAVKHLGE--GASIINISSVVTSITPPASAVYSGTKGAVDAITGVLALELGPRKIRVN 188 Query: 186 GIAPGAILTDALKS--VITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQI 243 I PG I+T+ S +I ++E ++L TP+ RLG+P DIA+ A+FL S A W++G+ Sbjct: 189 AINPGMIVTEGTHSAGIIGSDLEAQVLGQTPLGRLGEPNDIASVAVFLASDDARWMTGEH 248 Query: 244 LTVSGG 249 L VSGG Sbjct: 249 LVVSGG 254 >4NBT-A nrPDB Length = 240 Score = 145 bits (366), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 92/245 (37%), Positives = 133/245 (54%), Gaps = 13/245 (5%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 +L+GK A+ITG G+G+ IA+ +A GA V+ D+ +H E Sbjct: 3 KLEGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDLGDLTYSHPNVE---------GMYL 53 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAG-GGGPKPFDMPMADFRRAYELNVFSFFHLS 126 ++T + I K GK+DILVNNAG M A + ++N+ F+L+ Sbjct: 54 NVTDVTGVEKFYQSVIDKYGKIDILVNNAGITKDAMTRKMTEAQWDAVIDVNLKGVFNLT 113 Query: 127 QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMA--FDLGEKNIRV 184 +LV P+M+ NG G I+ I+S+ NI +YA++KA L A F L N+RV Sbjct: 114 RLVGPQMQTNGYGSIINISSVVGVFGNIGQANYAATKAGVIGLTMTWAKEFALKGANVRV 173 Query: 185 NGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQIL 244 N IAPG I+TD LK+V ++ K T + RLGQP++IA ALFL S AS+V+GQ + Sbjct: 174 NAIAPGYIMTDILKTV-PQDLLDKFAALTMLNRLGQPEEIAKVALFLASDDASYVTGQTI 232 Query: 245 TVSGG 249 V+GG Sbjct: 233 NVNGG 237 >2EW8-A nrPDB Length = 249 Score = 142 bits (359), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 96/256 (37%), Positives = 137/256 (53%), Gaps = 20/256 (7%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDI----NADAANHVVDEIQQLGGQAF 63 RL K A+ITG GIG+ IA FA GA + ++D+ A+AA I+ LG + Sbjct: 4 RLKDKLAVITGGANGIGRAIAERFAVEGADIAIADLVPAPEAEAA------IRNLGRRVL 57 Query: 64 ACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSF 122 +CD++ ++ A IS G+ DILVNNAG PFD + +++ +E+NV S Sbjct: 58 TVKCDVSQPGDVEAFGKQVISTFGRCDILVNNAGIYPLIPFDELTFEQWKKTFEINVDSG 117 Query: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182 F +++ P M++NG G I+ +TS K T Y S+KAA R +A DLG+ I Sbjct: 118 FLMAKAFVPGMKRNGWGRIINLTSTTYWLKIEAYTHYISTKAANIGFTRALASDLGKDGI 177 Query: 183 RVNGIAPGAILT-----DALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAAS 237 VN IAP + T AL ++ ++ MLQ P RL P D+ AA FL S AS Sbjct: 178 TVNAIAPSLVRTATTEASALSAMF--DVLPNMLQAIP--RLQVPLDLTGAAAFLASDDAS 233 Query: 238 WVSGQILTVSGGGVQE 253 +++GQ L V GG V+ Sbjct: 234 FITGQTLAVDGGMVRH 249 >2C07-A nrPDB Length = 285 Score = 140 bits (352), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 77/241 (31%), Positives = 138/241 (57%), Gaps = 2/241 (0%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDI 69 + K A++TGAG GIG+EIA A + + V+ + + VVDEI+ G ++ D+ Sbjct: 43 ENKVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKSFGYESSGYAGDV 102 Query: 70 TSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQL 128 + ++E+S + + +++ VDILVNNAG F M ++ N+ S F+++Q Sbjct: 103 SKKEEISEVINKILTEHKNVDILVNNAGITRDNLFLRMKNDEWEDVLRTNLNSLFYITQP 162 Query: 129 VAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIA 188 ++ M N G I+ I+S+ N+ +Y+SSKA +++A +L +NI VN IA Sbjct: 163 ISKRMINNRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKELASRNITVNAIA 222 Query: 189 PGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSG 248 PG I +D + I+ +I++ ++ + P R+G P+++AN A FL S + +++G++ + G Sbjct: 223 PGFISSD-MTDKISEQIKKNIISNIPAGRMGTPEEVANLACFLSSDKSGYINGRVFVIDG 281 Query: 249 G 249 G Sbjct: 282 G 282 >1GEE-A nrPDB Length = 261 Score = 132 bits (333), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 82/245 (33%), Positives = 135/245 (55%), Gaps = 4/245 (1%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVS-DINADAANHVVDEIQQLGGQAFACRC 67 L+GK +ITG+ G+GK +AI FAT A VVV+ D AN V++EI+++GG+A A + Sbjct: 5 LEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKVGGEAIAVKG 64 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGP-KPFDMPMADFRRAYELNVF-SFFHL 125 D+T E ++ L AI + GK+D+++NNAG P +M ++D+ + + N+ +F Sbjct: 65 DVTVESDVINLVQSAIKEFGKLDVMINNAGLENPVSSHEMSLSDWNKVIDTNLTGAFLGS 124 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 + + +E + G ++ ++S+ + YA+SK + +A + K IRVN Sbjct: 125 REAIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVN 184 Query: 186 GIAPGAILTDA-LKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQIL 244 I PGAI T + PE + P+ +G+P++IA A +L S AS+V+G L Sbjct: 185 NIGPGAINTPINAEKFADPEQRADVESMIPMGYIGEPEEIAAVAAWLASSEASYVTGITL 244 Query: 245 TVSGG 249 GG Sbjct: 245 FADGG 249 >2AE2-A nrPDB Length = 260 Score = 132 bits (331), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 84/247 (34%), Positives = 132/247 (53%), Gaps = 6/247 (2%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 L+G A++TG GIG I A+ GASV N N + + + G + A CD Sbjct: 7 LEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKVEASVCD 66 Query: 69 ITSEQELSALADFAISKL-GKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLS 126 ++S E L + + GK++ILVNNAG K D + D+ +N + +HLS Sbjct: 67 LSSRSERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINFEAAYHLS 126 Query: 127 QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNG 186 L P ++ + G ++ I+S++ Y ++K A L R +AF+ + NIRVNG Sbjct: 127 VLAHPFLKASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAFEWAKDNIRVNG 186 Query: 187 IAPGAILTDALKSVIT-PEIEQ---KMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQ 242 + PG I T ++ I PE ++ K++ +RR+G+P+++A FLC PAAS+V+GQ Sbjct: 187 VGPGVIATSLVEMTIQDPEQKENLNKLIDRCALRRMGEPKELAAMVAFLCFPAASYVTGQ 246 Query: 243 ILTVSGG 249 I+ V GG Sbjct: 247 IIYVDGG 253 >3OSU-A nrPDB Length = 246 Score = 131 bits (329), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 77/240 (32%), Positives = 131/240 (54%), Gaps = 3/240 (1%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINA-DAANHVVDEIQQLGGQAFACRCDIT 70 K A++TGA GIG+ IA+ A G +V V+ + + A VV+EI+ G +FA + ++ Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVA 64 Query: 71 SEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQLV 129 E+ A+ +S+ G +D+LVNNAG M ++ + N+ F+ Q Sbjct: 65 DADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQKA 124 Query: 130 APEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAP 189 P+M + G I+ ++S+ N +Y ++KA L ++ A +L + I VN +AP Sbjct: 125 TPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAVAP 184 Query: 190 GAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 G I++D + ++ E++++ML P+ R GQ DIAN FL S A +++GQ + V+GG Sbjct: 185 GFIVSD-MTDALSDELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITGQTIHVNGG 243 >5U9P-A nrPDB Length = 265 Score = 130 bits (328), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 83/247 (33%), Positives = 129/247 (52%), Gaps = 2/247 (0%) Query: 5 DNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFA 64 D RLDG+ A+ITG+G GIG +A A AGA++V++D N + A + + G A Sbjct: 14 DRFRLDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARRFRDEGFAADH 73 Query: 65 CRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFF 123 D+ ++ A D +++G +DILVNNAG P D D+ +N+ F Sbjct: 74 AVFDVAEHAQVRAAIDEFEARVGAIDILVNNAGIQRRAPLDAFEPDDWHALMRVNLDGVF 133 Query: 124 HLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIR 183 +++Q VA M G G I+ I S+ +E + YA++K A L + M D I+ Sbjct: 134 NVAQAVARHMIARGHGKIINICSVQSELARPTIAPYAATKGAVRMLTKGMCADWARYGIQ 193 Query: 184 VNGIAPGAILTDALKSVI-TPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQ 242 NG+APG T+ ++++ + + TP R GQ ++ AA+FL S A+ +V+GQ Sbjct: 194 ANGLAPGYFETELNRALVDDAAFSDWLCKRTPAGRWGQVDELCGAAIFLASAASDFVNGQ 253 Query: 243 ILTVSGG 249 L V GG Sbjct: 254 TLFVDGG 260 >2ZAT-A nrPDB Length = 260 Score = 130 bits (327), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 85/252 (33%), Positives = 131/252 (51%), Gaps = 9/252 (3%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 L+ K A++T + GIG IA A GA VVVS + + V +Q G C Sbjct: 12 LENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTVCH 71 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-----DMPMADFRRAYELNVFSFF 123 + ++ L A++ G VDILV+NA PF D + + +NV + Sbjct: 72 VGKAEDRERLVAMAVNLHGGVDILVSNAA---VNPFFGNIIDATEEVWDKILHVNVKATV 128 Query: 124 HLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIR 183 +++ V PEMEK GGG +L ++S+ A + N+ Y SK A L +N+A +L +NIR Sbjct: 129 LMTKAVVPEMEKRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIR 188 Query: 184 VNGIAPGAILTDALKSVITPEIEQKMLQHT-PIRRLGQPQDIANAALFLCSPAASWVSGQ 242 VN +APG I T+ + + + ++ ++ + IRRLG P+D A FLCS AS+++G+ Sbjct: 189 VNCLAPGLIKTNFSQVLWMDKARKEYMKESLRIRRLGNPEDCAGIVSFLCSEDASYITGE 248 Query: 243 ILTVSGGGVQEL 254 + V GG L Sbjct: 249 TVVVGGGTASRL 260 >4AVY-A nrPDB Length = 242 Score = 129 bits (324), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 89/245 (36%), Positives = 132/245 (53%), Gaps = 23/245 (9%) Query: 11 GKCAIITGAGAGIGKEIAITFATAGASVVVSDINAD---AANHVVDEIQQLGGQAFACRC 67 G+ ++TG +GIG IA+ FA GA VV ++AD A H ++L Sbjct: 11 GQQVLVTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHAPRHPRIRREEL--------- 61 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQ 127 DIT Q L L L ++D+LVNNAG + + +A F R LN+ + SQ Sbjct: 62 DITDSQRLQRL----FEALPRLDVLVNNAGISRDRE-EYDLATFERVLRLNLSAAMLASQ 116 Query: 128 LVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGI 187 L P + + GG IL I SM + + + +Y++SK A L R++A + + IRVN I Sbjct: 117 LARPLLAQRGGS-ILNIASMYSTFGSADRPAYSASKGAIVQLTRSLACEYAAERIRVNAI 175 Query: 188 APGAI---LTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQIL 244 APG I L LK+ + E ++++Q TP+ R G+ ++A+AA FLC P AS+V+G +L Sbjct: 176 APGWIDTPLGAGLKADV--EATRRIMQRTPLARWGEAPEVASAAAFLCGPGASFVTGAVL 233 Query: 245 TVSGG 249 V GG Sbjct: 234 AVDGG 238 >3FTP-A nrPDB Length = 270 Score = 127 bits (320), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 84/244 (34%), Positives = 131/244 (53%), Gaps = 6/244 (2%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 LD + AI+TGA GIG+ IA+ A GA V+ + A + +Q G + + Sbjct: 26 LDKQVAIVTGASRGIGRAIALELARRGAMVIGTATTEAGAEGIGAAFKQAGLEGRGAVLN 85 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD--FRRAYELNVFSFFHLS 126 + + AL + + + G +++LVNNAG + M M D + + N+ + F LS Sbjct: 86 VNDATAVDALVESTLKEFGALNVLVNNAGITQDQ-LAMRMKDDEWDAVIDTNLKAVFRLS 144 Query: 127 QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNG 186 + V M K GG I+ ITS+ N +YA++KA + + R +A ++G + I VN Sbjct: 145 RAVLRPMMKARGGRIVNITSVVGSAGNPGQVNYAAAKAGVAGMTRALAREIGSRGITVNC 204 Query: 187 IAPGAILTDALKSVITPEIEQKMLQ-HTPIRRLGQPQDIANAALFLCSPAASWVSGQILT 245 +APG I TD K + P+ +Q L+ P+ RLG P+DIA+A FL SP A +++G L Sbjct: 205 VAPGFIDTDMTKGL--PQEQQTALKTQIPLGRLGSPEDIAHAVAFLASPQAGYITGTTLH 262 Query: 246 VSGG 249 V+GG Sbjct: 263 VNGG 266 >3O4R-A nrPDB Length = 261 Score = 127 bits (318), Expect = 6e-30, Method: Compositional matrix adjust. Identities = 85/252 (33%), Positives = 130/252 (51%), Gaps = 9/252 (3%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 L K A++T + GIG IA A GA VVVS + V +Q G C Sbjct: 13 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 72 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-----DMPMADFRRAYELNVFSFF 123 + ++ L A+ G +DILV+NA PF D+ + + ++NV + Sbjct: 73 VGKAEDRERLVATAVKLHGGIDILVSNAA---VNPFFGSIMDVTEEVWDKTLDINVKAPA 129 Query: 124 HLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIR 183 +++ V PEMEK GGG ++ ++S+AA + + + Y SK A L + +A +L +NIR Sbjct: 130 LMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIR 189 Query: 184 VNGIAPGAILTDALKSV-ITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQ 242 VN +APG I T + + + E E+ M + IRRLG+P+D A FLCS AS+++G+ Sbjct: 190 VNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGE 249 Query: 243 ILTVSGGGVQEL 254 + V GG L Sbjct: 250 TVVVGGGTPSRL 261 >4NBV-A nrPDB Length = 246 Score = 127 bits (318), Expect = 7e-30, Method: Compositional matrix adjust. Identities = 86/244 (35%), Positives = 126/244 (51%), Gaps = 2/244 (0%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 ++L G+ AIITGA AGIG A FA GA VV+ D+ + G A R Sbjct: 1 MKLQGRVAIITGAAAGIGFATAQRFAEDGAIVVLCDVQEARVREAAARLAATGATVSAYR 60 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAG-GGGPKPFDMPMADFRRAYELNVFSFFHL 125 D+T E+ A+ ++ +VDILVNNAG + M A F ++N+ F+ Sbjct: 61 VDVTRRDEVDAMVAAVLAAHQRVDILVNNAGITKDARLAKMTEAQFDAVIDVNLKGVFNC 120 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 +Q VA M + G GVIL +S+ N T+YA+SK + A +LG K +RVN Sbjct: 121 AQAVAGLMTEQGKGVILNASSVVGLYGNFGQTNYAASKFGVIGFTKTWARELGPKGVRVN 180 Query: 186 GIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILT 245 + PG + T+ L++V ++ M +RRL +P +IA+ FL S AS+V+G + Sbjct: 181 AVCPGFVNTEILQTV-PDKVLDGMTSSCWLRRLAEPAEIASIYAFLASDDASYVNGVAIE 239 Query: 246 VSGG 249 SGG Sbjct: 240 ASGG 243 >3WOH-A nrPDB Length = 251 Score = 126 bits (317), Expect = 9e-30, Method: Compositional matrix adjust. Identities = 78/246 (31%), Positives = 131/246 (53%), Gaps = 11/246 (4%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADA-ANHVVDEIQQLGGQAFACRC 67 L GK A++TG G+G+ +A+ A GA+V + ++ D+ A EI++LGG A + RC Sbjct: 9 LSGKVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLGGTARSYRC 68 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAG----GGGPKPFDMPMADFRRAYELNVFSFF 123 D++ ++++ + LG VDILVNNAG G D D+ N+ F Sbjct: 69 DVSDAEQVTRCVKAVTADLGPVDILVNNAGIIRDGLAASIKD---EDYDAVMNTNLKGAF 125 Query: 124 HLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIR 183 + + G I+ I+S++ + +YAS+KA L +++A +L E+N+R Sbjct: 126 LFIKACYFGFIRKRSGSIINISSVSGVFGSAGQANYASAKAGLIGLTKSIAKELAERNVR 185 Query: 184 VNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQI 243 N +APG I TD + ++ + K L P+RR G+P ++A FL +S+++GQ+ Sbjct: 186 CNAVAPGLIATDMTQDLVD---DSKRLDPVPMRRFGRPDEVAGLVAFLAGDESSYITGQV 242 Query: 244 LTVSGG 249 + V GG Sbjct: 243 VCVDGG 248 >5T5Q-A nrPDB Length = 247 Score = 126 bits (316), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 78/249 (31%), Positives = 136/249 (54%), Gaps = 10/249 (4%) Query: 4 SDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG--Q 61 S + + ++TGA GIG+ IA F +GA++V++D++ + + LG + Sbjct: 2 SMKFEFENRTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFA---ASLGSPER 58 Query: 62 AFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVF 120 + D +S + A+ + G +D LV +AG KPF +M AD+ R +N+ Sbjct: 59 IATIKADASSADDAEKTVALAMERFGGIDFLVPSAGIYQAKPFAEMSDADWHRTISINLD 118 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 F+L + P ++++ I+T+ S+AA Y ++K A + R ++ +L K Sbjct: 119 GVFYLCKRALPALKEDSS--IVTLASLAAYRGAYVNAHYGATKGAMVSMTRALSRELAPK 176 Query: 181 NIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVS 240 RVNG++PG I T ++ +++ M Q TP++RLG+P +IA+ FLCSPAAS+V+ Sbjct: 177 T-RVNGVSPGIIETPMTSELLKTRMDETMTQ-TPLKRLGKPSEIASVIAFLCSPAASFVT 234 Query: 241 GQILTVSGG 249 G+ + V+GG Sbjct: 235 GETIQVNGG 243 >2CDH-G nrPDB Length = 244 Score = 125 bits (314), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 81/238 (34%), Positives = 128/238 (53%), Gaps = 4/238 (1%) Query: 15 IITGAGAGIGKEIAITFATAGASVVVSDI-NADAANHVVDEIQQLGGQAFACRCDITSEQ 73 ++TGA GIGK IA++ AG V+V+ +A AA V +I+ GGQA D++ E Sbjct: 5 VVTGASRGIGKAIALSLGKAGCKVLVNYARSAKAAEEVSKQIEAYGGQAITFGGDVSKEA 64 Query: 74 ELSALADFAISKLGKVDILVNNAG-GGGPKPFDMPMADFRRAYELNVFSFFHLSQLVAPE 132 ++ A+ AI G +D++VNNAG M + + +LN+ F +Q Sbjct: 65 DVEAMMKTAIDAWGTIDVVVNNAGITRDTLLIRMKKSQWDEVIDLNLTGVFLCTQAATKI 124 Query: 133 MEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPGAI 192 M K G I+ I S+ NI +YA++KA + A + +NI VN + PG I Sbjct: 125 MMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNINVNVVCPGFI 184 Query: 193 LTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLC-SPAASWVSGQILTVSGG 249 +D + + + ++E+K+L P+ R GQP+++A FL SPAAS+++GQ T+ GG Sbjct: 185 ASD-MTAKLGEDMEKKILGTIPLGRTGQPENVAGLVEFLALSPAASYITGQAFTIDGG 241 >4JRO-A nrPDB Length = 271 Score = 125 bits (313), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 81/252 (32%), Positives = 132/252 (52%), Gaps = 3/252 (1%) Query: 2 FNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVS-DINADAANHVVDEIQQLGG 60 F S+ + L GK A++TG GIG++IAI A GA++ + + + +AA + + G Sbjct: 20 FQSNAMTLQGKVAVVTGGSRGIGRDIAINLAKEGANIFFNYNGSPEAAEETAKLVAEHGV 79 Query: 61 QAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNV 119 + A + ++ +++ A AI + G+VDILVNNAG M ++ +N+ Sbjct: 80 EVEAMKANVAIAEDVDAFFKQAIERFGRVDILVNNAGITRDNLLMRMKEDEWDDVININL 139 Query: 120 FSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGE 179 F ++ V+ M K G I+ + S+ N +Y +SKA L + A +L Sbjct: 140 KGTFLCTKAVSRTMMKQRAGKIINMASVVGLIGNAGQANYVASKAGVIGLTKTTARELAP 199 Query: 180 KNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 + I VN +APG I TD + + + ++ ML P+ G +DIANA LFL S A+ ++ Sbjct: 200 RGINVNAVAPGFITTD-MTDKLDEKTKEAMLAQIPLGAYGTTEDIANAVLFLASDASKYI 258 Query: 240 SGQILTVSGGGV 251 +GQ L+V GG V Sbjct: 259 TGQTLSVDGGMV 270 >5OJG-A nrPDB Length = 260 Score = 125 bits (313), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 83/253 (32%), Positives = 129/253 (50%), Gaps = 7/253 (2%) Query: 4 SDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAF 63 S+ R +GK AI+T A GIG IA GASVV+ N + ++ ++ G Sbjct: 3 SNCRRFEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKV 62 Query: 64 A-CRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD--FRRAYELNVF 120 A I S + L DF + K GK++ILVNN G + ++D + + +E+NV Sbjct: 63 AGIAGHIASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVK 122 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 + F +++LV P + K GGG I+ S +A + +Y +K L R +A L + Sbjct: 123 AGFQMTKLVHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKD 182 Query: 181 NIRVNGIAPGAILTDALKSVI----TPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAA 236 NIRVNGIAPG I T + + E E +Q + RLG P D A +L S + Sbjct: 183 NIRVNGIAPGVIKTKMSQVLWDGGEDAEKELTDIQEIALGRLGVPDDCAGTVAYLASDDS 242 Query: 237 SWVSGQILTVSGG 249 S+++G+++ ++GG Sbjct: 243 SYITGEMIIIAGG 255 >4RZH-A nrPDB Length = 247 Score = 123 bits (308), Expect = 8e-29, Method: Compositional matrix adjust. Identities = 83/246 (33%), Positives = 133/246 (54%), Gaps = 7/246 (2%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDI-NADAANHVVDEIQQLGGQAFACRC 67 L + A++TGA GIGK A+ A G VVV+ ++ AA+ VV EI GG+A A + Sbjct: 4 LTAQVALVTGASRGIGKATALALAATGMKVVVNYAQSSTAADAVVAEIIANGGEAIAVQA 63 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAG-GGGPKPFDMPMADFRRAYELNVFSFFHLS 126 ++ + E+ L + K ++D+LVNNAG M + D++ +LN+ F + Sbjct: 64 NVANADEVDQLIKTTLDKFSRIDVLVNNAGITRDTLLLRMKLEDWQAVIDLNLTGVFLCT 123 Query: 127 QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNG 186 + V+ M K G I+ ITS+A N +Y+++KA + +A +L + + VN Sbjct: 124 KAVSKLMLKQKSGRIINITSVAGMMGNPGQANYSAAKAGVIGFTKTVAKELASRGVTVNA 183 Query: 187 IAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCS-PAASWVSGQILT 245 +APG I TD +++ I LQ P+ R GQP+++A FL + PAA++++GQ Sbjct: 184 VAPGFIATDMTENLNAEPI----LQFIPLARYGQPEEVAGTIRFLATDPAAAYITGQTFN 239 Query: 246 VSGGGV 251 V GG V Sbjct: 240 VDGGMV 245 >3RSH-A nrPDB Length = 251 Score = 123 bits (308), Expect = 9e-29, Method: Compositional matrix adjust. Identities = 83/247 (33%), Positives = 126/247 (51%), Gaps = 5/247 (2%) Query: 4 SDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAF 63 S + L+GK A++TGA GIGK IA A GA V+ + + A + D LG Sbjct: 5 SQFMNLEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISD---YLGDNGK 61 Query: 64 ACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSF 122 ++T+ + + A+ + G VDILVNNAG M ++ E N+ S Sbjct: 62 GMALNVTNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSI 121 Query: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182 F LS+ V M K G I+ + S+ N +YA++KA ++MA ++ + + Sbjct: 122 FRLSKAVLRGMMKKRQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVASRGV 181 Query: 183 RVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQ 242 VN +APG I TD K+ + E L P RLG P++IA+A FL SP A++++G+ Sbjct: 182 TVNTVAPGFIETDMTKA-LNDEQRTATLAQVPAGRLGDPREIASAVAFLASPEAAYITGE 240 Query: 243 ILTVSGG 249 L V+GG Sbjct: 241 TLHVNGG 247 >3UF0-A nrPDB Length = 273 Score = 122 bits (307), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 85/245 (34%), Positives = 132/245 (53%), Gaps = 8/245 (3%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 L G+ A++TGAG+GIG+ IA +A AGA V+ D V DEI GG A A D Sbjct: 29 LAGRTAVVTGAGSGIGRAIAHGYARAGAHVLAWG-RTDGVKEVADEIADGGGSAEAVVAD 87 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFHLSQ 127 + + + +A+ ++ +VD+LVNNAG P + + + +R +N+ + + LS+ Sbjct: 88 LADLEGAANVAE-ELAATRRVDVLVNNAGIIARAPAEEVSLGRWREVLTVNLDAAWVLSR 146 Query: 128 LVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGI 187 M +G G I+TI SM + N+ +YA+SK A L R +A + + + VN + Sbjct: 147 SFGTAMLAHGSGRIVTIASMLSFQGGRNVAAYAASKHAVVGLTRALASEWAGRGVGVNAL 206 Query: 188 APGAIL---TDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQIL 244 APG ++ T AL++ E ++ P R P+D+ A+FL S AAS+V GQ+L Sbjct: 207 APGYVVTANTAALRA--DDERAAEITARIPAGRWATPEDMVGPAVFLASDAASYVHGQVL 264 Query: 245 TVSGG 249 V GG Sbjct: 265 AVDGG 269 >2HQ1-A nrPDB Length = 247 Score = 122 bits (306), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 73/245 (29%), Positives = 131/245 (53%), Gaps = 3/245 (1%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAA-NHVVDEIQQLGGQAFAC 65 ++L GK AI+TG+ G+GK IA GA++V++ A + + +E + G Sbjct: 1 MQLKGKTAIVTGSSRGLGKAIAWKLGNMGANIVLNGSPASTSLDATAEEFKAAGINVVVA 60 Query: 66 RCDITSEQELSALADFAISKLGKVDILVNNAG-GGGPKPFDMPMADFRRAYELNVFSFFH 124 + D+ + +++ + A+ G++DILVNNAG M D+ N+ S + Sbjct: 61 KGDVKNPEDVENMVKTAMDAFGRIDILVNNAGITRDTLMLKMSEKDWDDVLNTNLKSAYL 120 Query: 125 LSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 ++ V+ M K G I+ ITS+A N +YA+SKA +++A + K I Sbjct: 121 CTKAVSKIMLKQKSGKIINITSIAGIIGNAGQANYAASKAGLIGFTKSIAKEFAAKGIYC 180 Query: 185 NGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQIL 244 N +APG I TD + V+ ++++ L + P++R G P+++AN FL S +++++GQ++ Sbjct: 181 NAVAPGIIKTD-MTDVLPDKVKEMYLNNIPLKRFGTPEEVANVVGFLASDDSNYITGQVI 239 Query: 245 TVSGG 249 + GG Sbjct: 240 NIDGG 244 >1AE1-A nrPDB Length = 273 Score = 121 bits (304), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 81/259 (31%), Positives = 131/259 (50%), Gaps = 10/259 (3%) Query: 1 MFNSDN---LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQ 57 M N +N L G A++TG GIG I A GA V N + ++ ++ Sbjct: 8 MMNCNNEGRWSLKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWRE 67 Query: 58 LGGQAFACRCDITSEQELSALADFAISKL-GKVDILVNNAGGGGPKPF-DMPMADFRRAY 115 G CD+ S E L GK++ILVNNAG K D D+ Sbjct: 68 KGLNVEGSVCDLLSRTERDKLMQTVAHVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIM 127 Query: 116 ELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAF 175 N + +HLSQ+ P ++ + G ++ ++S+A + +++ Y++SK A + + +++A Sbjct: 128 GTNFEAAYHLSQIAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLAC 187 Query: 176 DLGEKNIRVNGIAPGAILTDALKSVITPEIEQK-----MLQHTPIRRLGQPQDIANAALF 230 + + NIRVN +APG ILT +++ I QK + TP+ R G+PQ+++ F Sbjct: 188 EWAKDNIRVNSVAPGVILTPLVETAIKKNPHQKEEIDNFIVKTPMGRAGKPQEVSALIAF 247 Query: 231 LCSPAASWVSGQILTVSGG 249 LC PAAS+++GQI+ GG Sbjct: 248 LCFPAASYITGQIIWADGG 266 >4Z9Y-A nrPDB Length = 253 Score = 121 bits (303), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 81/248 (32%), Positives = 130/248 (52%), Gaps = 5/248 (2%) Query: 5 DNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFA 64 ++ L GK A+ITG G+G+ +AI A AG +V +N ++++ LG + + Sbjct: 4 NSFDLQGKVALITGCDTGLGQGMAIGLAQAGCDIV--GVNIVEPKDTIEKVTALGRRFLS 61 Query: 65 CRCDITSEQELSALADFAISKLGKVDILVNNAGG-GGPKPFDMPMADFRRAYELNVFSFF 123 D+++ + L + A+++ G VDILVNNAG + ++ LN+ S F Sbjct: 62 LTADMSNVSGHAELVEKAVAEFGHVDILVNNAGIIRREDAIEFSEKNWDDVMNLNIKSVF 121 Query: 124 HLSQLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182 +SQ VA + K G GG I+ I SM + I + SY +SK+A + R MA + + I Sbjct: 122 FMSQTVARQFIKQGKGGKIINIASMLSFQGGIRVPSYTASKSAVMGVTRLMANEWAKHGI 181 Query: 183 RVNGIAPGAILTDALKSVITPEIEQK-MLQHTPIRRLGQPQDIANAALFLCSPAASWVSG 241 VN IAPG + T+ + + E K +L P R G PQD+ ++FL S A+ +++G Sbjct: 182 NVNAIAPGYMATNNTQQLRADEERSKEILDRIPAGRWGLPQDLMGPSVFLASSASDYING 241 Query: 242 QILTVSGG 249 + V GG Sbjct: 242 YTIAVDGG 249 >4IIN-A nrPDB Length = 271 Score = 120 bits (302), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 77/250 (30%), Positives = 133/250 (53%), Gaps = 3/250 (1%) Query: 2 FNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVS-DINADAANHVVDEIQQLGG 60 F S+ ++ GK +ITGA GIG EIA T A+ G V ++ NA+ A+ + +E+++ G Sbjct: 20 FQSNAMQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGY 79 Query: 61 QAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPK-PFDMPMADFRRAYELNV 119 +A + D SE + + G + LVNNAG K M DF + N+ Sbjct: 80 KAAVIKFDAASESDFIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNL 139 Query: 120 FSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGE 179 S F + M K+ G ++ + S+ E N+ T+Y++SK + ++ A++ Sbjct: 140 TSAFIGCREALKVMSKSRFGSVVNVASIIGERGNMGQTNYSASKGGMIAMSKSFAYEGAL 199 Query: 180 KNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 +NIR N + PG I TD + + + E++ +++ P+ RLG +++A A FL S +S++ Sbjct: 200 RNIRFNSVTPGFIETD-MNANLKDELKADYVKNIPLNRLGSAKEVAEAVAFLLSDHSSYI 258 Query: 240 SGQILTVSGG 249 +G+ L V+GG Sbjct: 259 TGETLKVNGG 268 >3OIC-A nrPDB Length = 258 Score = 120 bits (302), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 77/241 (31%), Positives = 126/241 (52%), Gaps = 3/241 (1%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINAD-AANHVVDEIQQLGGQAFACRCDIT 70 KCA++TG+ G+GK AI A G ++V++ + AA +EI++LG + + ++ Sbjct: 5 KCALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALETAEEIEKLGVKVLVVKANVG 64 Query: 71 SEQELSALADFAISKLGKVDILVNNAGGGGPKP-FDMPMADFRRAYELNVFSFFHLSQLV 129 ++ + G++D+ VNNA G +P ++ + +N + +Q Sbjct: 65 QPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELEETHWDWTMNINAKALLFCAQEA 124 Query: 130 APEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAP 189 A MEKNGGG I++I+S+ + N T+ SKAA L R +A +L K I VN ++ Sbjct: 125 AKLMEKNGGGHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAVELSPKQIIVNAVSG 184 Query: 190 GAILTDALKSVITPE-IEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSG 248 GAI TDALK E + + Q+TP R+ + +D+ + FL S A + GQ + V G Sbjct: 185 GAIDTDALKHFPNREDLLEDARQNTPAGRMVEIKDMVDTVEFLVSSKADMIRGQTIIVDG 244 Query: 249 G 249 G Sbjct: 245 G 245 >1DOH-A nrPDB Length = 283 Score = 120 bits (301), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 80/258 (31%), Positives = 134/258 (51%), Gaps = 21/258 (8%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINA-DAANHVVDEIQQLGGQAFACRC 67 L+GK A++TGAG GIG+E+A+ G V+V+ N+ ++A VV I++ G A + Sbjct: 27 LEGKVALVTGAGRGIGREMAMELGRRGCKVIVNYANSTESAEEVVAAIKKNGSDAACVKA 86 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAG---GGGPKPFDMPMADFRRAYELNVFSFFH 124 ++ +++ + + A+ GK+DI+ +N+G G K D+ +F R + +N F Sbjct: 87 NVGVVEDIVRMFEEAVKIFGKLDIVCSNSGVVSFGHVK--DVTPEEFDRVFTINTRGQFF 144 Query: 125 LSQLVAPEMEKNGGGVILTITSMAAENKNI-NMTSYASSKAAASHLVRNMAFDLGEKNIR 183 +++ +E GG ++ + S+ + K + Y+ SK A R MA D+ +K I Sbjct: 145 VAREAYKHLEI--GGRLILMGSITGQAKAVPKHAVYSGSKGAIETFARCMAIDMADKKIT 202 Query: 184 VNGIAPGAILTDALKSVITPEI------------EQKMLQHTPIRRLGQPQDIANAALFL 231 VN +APG I TD +V I E +Q +P+RR+G P DIA FL Sbjct: 203 VNVVAPGGIKTDMYHAVCREYIPNGENLSNEEVDEYAAVQWSPLRRVGLPIDIARVVCFL 262 Query: 232 CSPAASWVSGQILTVSGG 249 S WV+G+++ + GG Sbjct: 263 ASNDGGWVTGKVIGIDGG 280 >1CYD-A nrPDB Length = 244 Score = 118 bits (296), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 83/248 (33%), Positives = 132/248 (53%), Gaps = 13/248 (5%) Query: 6 NLRLDGKCAIITGAGAGIGKEIAITFATAGASVV-VSDINADAANHVVDEIQQLGGQAFA 64 L G A++TGAG GIG++ +GA VV V+ N+D +V ++ G Sbjct: 2 KLNFSGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSD----LVSLAKECPGIEPV 57 Query: 65 CRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFF 123 C D+ + A+ +G VD+LVNNA +PF ++ F R++ +N+ S F Sbjct: 58 C-VDLGDWDA----TEKALGGIGPVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNLRSVF 112 Query: 124 HLSQLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182 +SQ+VA +M G G I+ ++SM A N+ +Y+S+K A + L + MA +LG I Sbjct: 113 QVSQMVARDMINRGVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMELGPHKI 172 Query: 183 RVNGIAPGAILTDALKSV-ITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSG 241 RVN + P +LTD K V PE +K+ + P+R+ + +D+ N+ LFL S ++ SG Sbjct: 173 RVNSVNPTVVLTDMGKKVSADPEFARKLKERHPLRKFAEVEDVVNSILFLLSDRSASTSG 232 Query: 242 QILTVSGG 249 + V G Sbjct: 233 GGILVDAG 240 >6CI9-A nrPDB Length = 259 Score = 117 bits (293), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 82/255 (32%), Positives = 126/255 (49%), Gaps = 11/255 (4%) Query: 1 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG 60 MF S L+G+ AI+TG GIG+ IA TFA AG VV++ N D + V ++ G Sbjct: 3 MFTS----LEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRG 58 Query: 61 QAFACRCDITSEQELSALADFAISKLGKVDILVNNAG---GGGPKPFDMPMADFRRAYEL 117 + A R D+T ++ +S+ G +DI+ NAG G + D+ D + + Sbjct: 59 KVTAVRADVTDPEDARRTVAETVSRHGGLDIVCANAGIFPSG--RLEDLTPDDIEQVLGV 116 Query: 118 NVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNI-NMTSYASSKAAASHLVRNMAFD 176 N ++ Q + +G G ++ +S+ + Y +SKAA +R A + Sbjct: 117 NFKGTVYIVQAALQALTASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAME 176 Query: 177 LGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAA 236 L K I +N + PG I+T+ L + ++Q M P RLG DI NAALF + A Sbjct: 177 LAPKKITINAVLPGNIMTEGLDEMGQDYLDQ-MASAIPAGRLGSVADIGNAALFFATDEA 235 Query: 237 SWVSGQILTVSGGGV 251 ++V+GQ L V GG V Sbjct: 236 AYVTGQTLVVDGGQV 250 >3WYE-A nrPDB Length = 256 Score = 117 bits (292), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 87/252 (34%), Positives = 130/252 (51%), Gaps = 12/252 (4%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITS 71 K A++TGAG GIGK IA+ G +V ++D N A V EI Q GG A A + D++ Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDVSD 62 Query: 72 EQELSALADFAISKLGKVDILVNNAGGGGPKP-FDMPMADFRRAYELNVFSFFHLSQLVA 130 ++ A + A LG D++VNNAG KP ++ D ++ Y +NVFS F Q Sbjct: 63 RDQVFAAVEQARKTLGGFDVIVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQAAV 122 Query: 131 PEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAP 189 +K G GG I+ S+AA +++Y+++K A L + A DL I VNG P Sbjct: 123 EAFKKEGHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAARDLAPLGITVNGYCP 182 Query: 190 GAILT------DA-LKSVITPEIEQKMLQHTPIRRLGQ---PQDIANAALFLCSPAASWV 239 G + T DA L + I + +++ LG+ P+D+A FL SP + ++ Sbjct: 183 GIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLASPDSDYM 242 Query: 240 SGQILTVSGGGV 251 +GQ L + GG V Sbjct: 243 TGQSLLIDGGMV 254 >3R3S-A nrPDB Length = 294 Score = 116 bits (291), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 80/247 (32%), Positives = 133/247 (53%), Gaps = 7/247 (2%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADA--ANHVVDEIQQLGGQAFAC 65 RL + A++TG +GIG+ AI +A GA V ++ + A+ A V I++ G +A Sbjct: 46 RLKDRKALVTGGDSGIGRAAAIAYAREGADVAINYLPAEEEDAQQVKALIEECGRKAVLL 105 Query: 66 RCDITSEQELSALADFAISKLGKVDILVNNAGGGG--PKPFDMPMADFRRAYELNVFSFF 123 D++ E +L A LG +DIL AG P+ D+ F++ + +NVF+ F Sbjct: 106 PGDLSDESFARSLVHKAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQTFAVNVFALF 165 Query: 124 HLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIR 183 ++Q P + K G I+T +S+ A + ++ YA++KAA + R +A + EK IR Sbjct: 166 WITQEAIPLLPK--GASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIR 223 Query: 184 VNGIAPGAILTD-ALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQ 242 VN +APG I T + T + + Q TP++R GQP ++A ++L S +S+V+ + Sbjct: 224 VNIVAPGPIWTALQISGGQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQESSYVTAE 283 Query: 243 ILTVSGG 249 + V GG Sbjct: 284 VHGVCGG 290 >4M8S-A nrPDB Length = 248 Score = 115 bits (288), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 89/244 (36%), Positives = 129/244 (52%), Gaps = 8/244 (3%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 L GK A++TGA GIG IA T A AGA V+ + + A + + + Q GG+ R Sbjct: 6 LSGKIALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGGEG---RVL 62 Query: 69 ITSEQEL--SALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHL 125 ++E E + +AD GK+DILVNNAG M ++ ++N+ S F Sbjct: 63 NSAEPETVENLIADIE-KTFGKLDILVNNAGITRDNLLMRMKEEEWDDIMQVNLKSVFRA 121 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 S+ V M K G I+ ITS+ N T+YA++KA ++MA ++G + I VN Sbjct: 122 SKAVLRGMMKQRAGRIINITSVVGVMGNAGQTNYAAAKAGLIGFSKSMAREVGSRGITVN 181 Query: 186 GIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILT 245 +APG I TD ++ + E Q T + R G QDIA+A LFL S A +++GQ L Sbjct: 182 CVAPGFIDTDMTRA-LPEETRQTFTAQTALGRFGDAQDIADAVLFLASDQAKYITGQTLH 240 Query: 246 VSGG 249 V+GG Sbjct: 241 VNGG 244 >4DMM-A nrPDB Length = 269 Score = 115 bits (288), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 89/247 (36%), Positives = 139/247 (56%), Gaps = 9/247 (3%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN-ADAANHVVDEIQQLGGQAFAC 65 L L + A++TGA GIG+ IA+ A AGA V V+ + A AA+ VV I GG+AFA Sbjct: 24 LPLTDRIALVTGASRGIGRAIALELAAAGAKVAVNYASSAGAADEVVAAIAAAGGEAFAV 83 Query: 66 RCDITSEQELSALADFAISKLGKVDILVNNAG-GGGPKPFDMPMADFRRAYELNVFSFFH 124 + D++ E E+ AL I + G++D+LVNNAG M D++ +LN+ F Sbjct: 84 KADVSQESEVEALFAAVIERWGRLDVLVNNAGITRDTLLLRMKRDDWQSVLDLNLGGVFL 143 Query: 125 LSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 S+ A M K G I+ I S+ E N +Y+++KA L + +A +L + I V Sbjct: 144 CSRAAAKIMLKQRSGRIINIASVVGEMGNPGQANYSAAKAGVIGLTKTVAKELASRGITV 203 Query: 185 NGIAPGAILTDALKSVITPEI-EQKMLQHTPIRRLGQPQDIANAALFLCS-PAASWVSGQ 242 N +APG I TD +T E+ +K+L+ P+ R G+ ++A FL + PAA++++GQ Sbjct: 204 NAVAPGFIATD-----MTSELAAEKLLEVIPLGRYGEAAEVAGVVRFLAADPAAAYITGQ 258 Query: 243 ILTVSGG 249 ++ + GG Sbjct: 259 VINIDGG 265 >3RWB-A nrPDB Length = 247 Score = 115 bits (287), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 89/255 (34%), Positives = 132/255 (51%), Gaps = 19/255 (7%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 RL GK A++TGA GIGK IA A GA+V+VSDINA+ A I G +A A Sbjct: 3 RLAGKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASI---GKKARAIAA 59 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF----DMPMADFRRAYELNVFSFF 123 DI+ + AL + G +DILVNNA PF D+ + +R+ ++N+ F Sbjct: 60 DISDPGSVKALFAEIQALTGGIDILVNNA---SIVPFVAWDDVDLDHWRKIIDVNLTGTF 116 Query: 124 HLSQLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182 +++ +M G G +++I S NM +Y ++K R +A +LG+ NI Sbjct: 117 IVTRAGTDQMRAAGKAGRVISIASNTFFAGTPNMAAYVAAKGGVIGFTRALATELGKYNI 176 Query: 183 RVNGIAPGAILTDALKSVITPEIEQ----KMLQHTPIRRLGQPQDIANAALFLCSPAASW 238 N + PG I +D +K+ +P E +MLQ ++ GQP+ IA+ FL S A W Sbjct: 177 TANAVTPGLIESDGVKA--SPHNEAFGFVEMLQ--AMKGKGQPEHIADVVSFLASDDARW 232 Query: 239 VSGQILTVSGGGVQE 253 ++GQ L V G V+ Sbjct: 233 ITGQTLNVDAGMVRH 247 >1GEG-A nrPDB Length = 256 Score = 115 bits (287), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 81/257 (31%), Positives = 122/257 (47%), Gaps = 22/257 (8%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITS 71 K A++TGAG GIGK IA+ G +V ++D N A V EI Q GG A A + D++ Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDVSD 62 Query: 72 EQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADF-RRAYELNVFSFFHLSQLVA 130 ++ A + A LG D++VNNAG P + + + Y +NV Q Sbjct: 63 RDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWGIQAAV 122 Query: 131 PEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAP 189 +K G GG I+ S A N + Y+SSK A L + A DL I VNG P Sbjct: 123 EAFKKEGHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGITVNGYCP 182 Query: 190 GAILTDALKSVITPEIEQKM---------------LQHTPIRRLGQPQDIANAALFLCSP 234 G + K+ + EI++++ + + RL +P+D+A +L SP Sbjct: 183 GIV-----KTPMWAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAACVSYLASP 237 Query: 235 AASWVSGQILTVSGGGV 251 + +++GQ L + GG V Sbjct: 238 DSDYMTGQSLLIDGGMV 254 >4BO1-A nrPDB Length = 269 Score = 115 bits (287), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 78/246 (31%), Positives = 130/246 (52%), Gaps = 4/246 (1%) Query: 6 NLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFAC 65 ++ L GK A++TGA GIG+ IA+ GA V+ + +A A + + ++ G + Sbjct: 22 SMSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGL 81 Query: 66 RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFH 124 D++S++ ++A + LG+ I+VNNAG M ++ N+ S + Sbjct: 82 VLDVSSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEWFDVVNTNLNSLYR 141 Query: 125 LSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 LS+ V M K G I+ I S+ N T+YA++KA R +A ++G + I V Sbjct: 142 LSKAVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAITV 201 Query: 185 NGIAPGAILTDALKSVITPEIEQK-MLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQI 243 N +APG I TD + + PE +++ +L P+ RLGQ ++IA FL S A++V+G Sbjct: 202 NAVAPGFIDTDMTREL--PEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGAT 259 Query: 244 LTVSGG 249 + V+GG Sbjct: 260 VPVNGG 265 >1Q7C-A nrPDB Length = 244 Score = 115 bits (287), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 81/245 (33%), Positives = 129/245 (52%), Gaps = 7/245 (2%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 + +GK A++TGA GIG+ IA T A GA V+ + + + A + D LG Sbjct: 1 MNFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISD---YLGANGKGLM 57 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD--FRRAYELNVFSFFH 124 ++T + ++ + ++ G+VDILVNNAG M M D + E N+ S F Sbjct: 58 LNVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLL-MRMKDEEWNDIIETNLSSVFR 116 Query: 125 LSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 LS+ V M K G I+TI S+ N ++A++KA +++A ++ + I V Sbjct: 117 LSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANFAAAKAGLIGFSKSLAREVASRGITV 176 Query: 185 NGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQIL 244 N +APG I TD ++ ++ + +L P RLG Q+IANA FL S A++++G+ L Sbjct: 177 NVVAPGFIETDMTRA-LSDDQRAGILAQVPAGRLGGAQEIANAVAFLASDEAAYITGETL 235 Query: 245 TVSGG 249 V+GG Sbjct: 236 HVNGG 240 >3U5T-A nrPDB Length = 267 Score = 114 bits (286), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 80/247 (32%), Positives = 123/247 (49%), Gaps = 18/247 (7%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDI-NADAANHVVDEIQQLGGQAFACRCDIT 70 K AI+TGA GIG IA A+ G +VV++ A AA V +I+ GG+A + D++ Sbjct: 28 KVAIVTGASRGIGAAIAARLASDGFTVVINYAGKAAAAEEVAGKIEAAGGKALTAQADVS 87 Query: 71 SEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPM--------ADFRRAYELNVFSF 122 + L A G VD+LVNNAG MP+ A F R +N+ Sbjct: 88 DPAAVRRLFATAEEAFGGVDVLVNNAG-------IMPLTTIAETGDAVFDRVIAVNLKGT 140 Query: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182 F+ + A + GG I+ +++ + + YA++KA + ++ +L ++I Sbjct: 141 FNTLREAAQRLRV--GGRIINMSTSQVGLLHPSYGIYAAAKAGVEAMTHVLSKELRGRDI 198 Query: 183 RVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQ 242 VN +APG TD + E+ + + P+ RLG PQDIA A FL P +WV+GQ Sbjct: 199 TVNAVAPGPTATDLFLEGKSDEVRDRFAKLAPLERLGTPQDIAGAVAFLAGPDGAWVNGQ 258 Query: 243 ILTVSGG 249 +L +GG Sbjct: 259 VLRANGG 265 >4FC7-A nrPDB Length = 277 Score = 114 bits (284), Expect = 5e-26, Method: Compositional matrix adjust. Identities = 81/257 (31%), Positives = 135/257 (52%), Gaps = 14/257 (5%) Query: 1 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG 60 +F D LR K A ITG G+GIG IA F G V++ + + V+ ++L G Sbjct: 19 LFCPDLLR--DKVAFITGGGSGIGFRIAEIFMRHGCHTVIA---SRSLPRVLTAARKLAG 73 Query: 61 QAFACRC-----DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRA 114 A RC D+ + + A D A+ + G++DIL+N A G P + F+ Sbjct: 74 -ATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTV 132 Query: 115 YELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMA 174 +++ F++S+++ + ++ GGVI+ IT+ S+KAA + R++A Sbjct: 133 MDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLA 192 Query: 175 FDLGEKNIRVNGIAPGAIL-TDALKSVITPEIE-QKMLQHTPIRRLGQPQDIANAALFLC 232 + G +NIRVN +APG I T+ L+ + P+ + +P++RLG +IA++ L+L Sbjct: 193 VEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLA 252 Query: 233 SPAASWVSGQILTVSGG 249 SP AS+V+G +L GG Sbjct: 253 SPLASYVTGAVLVADGG 269 >1O5I-A nrPDB Length = 249 Score = 112 bits (280), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 68/239 (28%), Positives = 124/239 (51%), Gaps = 16/239 (6%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITS 71 K ++ A GIG+ +A + GA V + N +E+ + G + CD+ Sbjct: 20 KGVLVLAASRGIGRAVADVLSQEGAEVTICARN--------EELLKRSGHRYVV-CDLRK 70 Query: 72 EQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFHLSQLVA 130 + D K+ +VDILV NAGG FD + DF+ A + + + + Sbjct: 71 D------LDLLFEKVKEVDILVLNAGGPKAGFFDELTNEDFKEAIDSLFLNMIKIVRNYL 124 Query: 131 PEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPG 190 P M++ G G I+ ITS + + N+ + S++ A + ++ ++F++ I VN +APG Sbjct: 125 PAMKEKGWGRIVAITSFSVISPIENLYTSNSARMALTGFLKTLSFEVAPYGITVNCVAPG 184 Query: 191 AILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 T+ +K +++ E ++++ P+RR+ +P++IA+ FLCS AS+++GQ + V GG Sbjct: 185 WTETERVKELLSEEKKKQVESQIPMRRMAKPEEIASVVAFLCSEKASYLTGQTIVVDGG 243 >6NRP-A nrPDB Length = 263 Score = 111 bits (277), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 75/241 (31%), Positives = 129/241 (53%), Gaps = 13/241 (5%) Query: 15 IITGAGAGIGKEIAITFATAGASVVVSDINADA-ANHVVDEIQQLGGQAFACRCDITSEQ 73 ++TG+ GIGK IA+ A AG V V + A A VV EIQ LG + D+ Q Sbjct: 28 LVTGSSRGIGKAIALQLAKAGFDVTVHARSRQAEAEQVVQEIQALGQNSHYLMFDVNERQ 87 Query: 74 ELSALADFAISKLGKVDILVNNAG----GGGPKPFDMPMADFRRAYELNVFSFFH-LSQL 128 + + + + + G +V NAG G P D D+ ++ F++ L L Sbjct: 88 TVQQILEQDVEQHGGFYGVVLNAGLTHDGAFPALTDQ---DWDEVISTSLDGFYNVLKPL 144 Query: 129 VAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIA 188 + P + GG I+T++S++ N +Y+++KA + +A +L ++ I VN +A Sbjct: 145 IMPMIHLRKGGRIVTLSSVSGIMGNRGQVNYSAAKAGLIGATKALALELAKRKITVNCVA 204 Query: 189 PGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSG 248 PG I T+ ++T E+++ L+ P++R+GQ ++A+ FLCS AS+V+ Q+++V+G Sbjct: 205 PGLIETE----MVTDEVKEHALKMIPLQRMGQVDEVASVVKFLCSDEASYVTRQVISVNG 260 Query: 249 G 249 G Sbjct: 261 G 261 >5YSS-A nrPDB Length = 256 Score = 111 bits (277), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 77/259 (29%), Positives = 127/259 (49%), Gaps = 15/259 (5%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDI-NADAANHVVDEIQQLGGQAFAC 65 + L GK A++TG+ +GIG IA A AGA+++++ + DAA D + Q G Sbjct: 1 MNLTGKTALVTGSTSGIGLGIAQVLAQAGATLILNGFGDVDAAK---DAVAQYGKTPGYH 57 Query: 66 RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFH 124 D++ E +++ + +A S+ G VDIL+NNAG P + P+ + +N+ S FH Sbjct: 58 GADLSDEAQIADMMRYAESEFGGVDILINNAGIQHVSPIETFPVDKWNAIIAINLSSVFH 117 Query: 125 LSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 ++L P M G I+ I S+ + ++Y ++K L + +A + + I Sbjct: 118 TTRLALPGMRARNWGRIINIASVHGLVASKEKSAYVAAKHGVVGLTKTIALETAQTEITC 177 Query: 185 NGIAPGAILTDALKSVI--------TPEIEQKML--QHTPIRRLGQPQDIANAALFLCSP 234 N + PG +LT ++ I PE + L + P R P+ + N ALFLCS Sbjct: 178 NALCPGWVLTPLVQQQIDKRIAEGAEPEAARDALLAEKQPSREFVTPEQLGNLALFLCSD 237 Query: 235 AASWVSGQILTVSGGGVQE 253 A+ V G + GG V + Sbjct: 238 GAAQVRGVAWNMDGGWVAQ 256 >1K2W-A nrPDB Length = 256 Score = 109 bits (272), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 78/255 (30%), Positives = 120/255 (47%), Gaps = 15/255 (5%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 +RLDGK A+ITG+ GIG+ A + GA V ++DIN +AA EI G A A Sbjct: 1 MRLDGKTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAAEI---GPAACAIA 57 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHL 125 D+T + + + + G +DILVNNA P ++ + R + +NV + Sbjct: 58 LDVTDQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGTLFM 117 Query: 126 SQLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 Q VA M G GG I+ + S A + Y ++KAA L ++ +L I V Sbjct: 118 MQAVARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNLIRHGINV 177 Query: 185 NGIAPGAILTDALKSVITP----------EIEQKMLQHTPIRRLGQPQDIANAALFLCSP 234 N IAPG + + V E ++++ P R+G+ +D+ A+FL +P Sbjct: 178 NAIAPGVVDGEHWDGVDAKFADYENLPRGEKKRQVGAAVPFGRMGRAEDLTGMAIFLATP 237 Query: 235 AASWVSGQILTVSGG 249 A ++ Q V GG Sbjct: 238 EADYIVAQTYNVDGG 252 >4K6F-A nrPDB Length = 255 Score = 109 bits (272), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 67/244 (27%), Positives = 125/244 (51%), Gaps = 10/244 (4%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVS-DINADAANHVVDEIQQLGGQAFACRCDIT 70 + A++TG G+G+ ++I AG VVV+ N A+ + E+ G + A D+ Sbjct: 12 RIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNTGADRWLTEMHAAGREFHAYPVDVA 71 Query: 71 SEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPM-----ADFRRAYELNVFSFFHL 125 + + +G VDILVNNAG DM + ++ N+ S F++ Sbjct: 72 DHDSCQQCIEKIVRDVGPVDILVNNAG----ITRDMTLRKLDKVNWDAVIRTNLDSVFNM 127 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 ++ V M + G G I+ I+S+ ++ T+YA++KA +++A ++ K + VN Sbjct: 128 TKPVCDGMVERGWGRIVNISSVNGSKGSVGQTNYAAAKAGMHGFTKSLALEIARKGVTVN 187 Query: 186 GIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILT 245 ++PG + T + ++ ++ K+L P RLG+P+++A +LCS A +V+G + Sbjct: 188 TVSPGYLATKMVTAIPQDILDTKILPQIPAGRLGKPEEVAALVAYLCSEEAGFVTGSNIA 247 Query: 246 VSGG 249 ++GG Sbjct: 248 INGG 251 >4TRR-A nrPDB Length = 269 Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 83/255 (32%), Positives = 136/255 (53%), Gaps = 15/255 (5%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 L+GK A++TGA +GIGKEIA+ A AGA+V ++D+N D AN V DEI + GG+A D Sbjct: 12 LNGKTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANAVADEINKAGGKAIGVAMD 71 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFHLSQ 127 +T+E+ ++ D G VDILV+NAG P + AD+++ ++V F ++ Sbjct: 72 VTNEEAVNTGIDKVAEAFGSVDILVSNAGIQIVNPIENYSFADWKKMQAIHVDGAFLTTK 131 Query: 128 LVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNG 186 M K+ GGV++ + S+ + + ++Y ++K L R +A + + N+R + Sbjct: 132 AALKHMYKDDRGGVVIYMGSVHSHEASPLKSAYVTAKHGLLGLARVLAKEGAKHNVRSHV 191 Query: 187 IAPGAILTDALKSVITPE------------IEQKMLQHTPIRRLGQPQDIANAALFLCSP 234 + PG + T + I PE I++ ML +T QD+A LFL + Sbjct: 192 VCPGFVRTPLVDKQI-PEQAKELGISEEEVIKKVMLGNTVDGVFTTVQDVAQTVLFLSAF 250 Query: 235 AASWVSGQILTVSGG 249 ++ ++GQ VS G Sbjct: 251 PSAALTGQSFIVSHG 265 >4E6P-A nrPDB Length = 259 Score = 107 bits (268), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 84/259 (32%), Positives = 126/259 (48%), Gaps = 25/259 (9%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 RL+GK A+ITG+ GIG+ A + GA+V ++DI+ + A EI G A+A + Sbjct: 5 RLEGKSALITGSARGIGRAFAEAYVREGATVAIADIDIERARQAAAEI---GPAAYAVQM 61 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDM-PMADF-RRAYE----LNVFS 121 D+T + + A + G +DILVNNA FD+ P+ + R +YE +NV Sbjct: 62 DVTRQDSIDAAIAATVEHAGGLDILVNNAA-----LFDLAPIVEITRESYEKLFAINVAG 116 Query: 122 FFHLSQLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 Q A +M G GG I+ + S A + Y ++KAA L ++ DL + Sbjct: 117 TLFTLQAAARQMIAQGRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAGLDLIKH 176 Query: 181 NIRVNGIAPGAIL------TDAL--KSVITPEIEQKML--QHTPIRRLGQPQDIANAALF 230 I VN IAPG + DAL + P E+K L + P R+G +D+ A+F Sbjct: 177 RINVNAIAPGVVDGEHWDGVDALFARYENRPRGEKKRLVGEAVPFGRMGTAEDLTGMAIF 236 Query: 231 LCSPAASWVSGQILTVSGG 249 L S + ++ Q V GG Sbjct: 237 LASAESDYIVSQTYNVDGG 255 >3LYL-A nrPDB Length = 247 Score = 107 bits (268), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 76/245 (31%), Positives = 130/245 (53%), Gaps = 4/245 (1%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 + L+ K A++TGA GIG E+A A+ GA+VV + + +A + +++ G +A Sbjct: 1 MSLNEKVALVTGASRGIGFEVAHALASKGATVVGTATSQASAEKFENSMKEKGFKARGLV 60 Query: 67 CDITSEQEL-SALADFAISKLGKVDILVNNAGGGGPK-PFDMPMADFRRAYELNVFSFFH 124 +I+ + + + A+ L +DILVNNAG M +++ N+ S F Sbjct: 61 LNISDIESIQNFFAEIKAENLA-IDILVNNAGITRDNLMMRMSEDEWQSVINTNLSSIFR 119 Query: 125 LSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 +S+ M K G I++I S+ N T+Y ++KA +++A+++ +NI V Sbjct: 120 MSKECVRGMMKKRWGRIISIGSVVGSAGNPGQTNYCAAKAGVIGFSKSLAYEVASRNITV 179 Query: 185 NGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQIL 244 N +APG I TD + +T E + + P ++G+P+DIA A FL S A +++GQ L Sbjct: 180 NVVAPGFIATD-MTDKLTDEQKSFIATKIPSGQIGEPKDIAAAVAFLASEEAKYITGQTL 238 Query: 245 TVSGG 249 V+GG Sbjct: 239 HVNGG 243 >3EMK-A nrPDB Length = 246 Score = 107 bits (267), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 77/246 (31%), Positives = 129/246 (52%), Gaps = 13/246 (5%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 L G+ A++TGA G+G+ IA GA V + + + E LG + F + Sbjct: 5 LTGRKALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAE---LGERIFVFPAN 61 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQ 127 ++ + + AL A ++G VDILVNNAG F M D+ +N+ S F+L++ Sbjct: 62 LSDREAVKALGQKAEEEMGGVDILVNNAGITRDGLFVRMSDEDWDAVLTVNLTSVFNLTR 121 Query: 128 LVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGI 187 + M + G I+ ITS+ N +Y +SKA +++A ++ +N+ VN I Sbjct: 122 ELTHPMMRRRNGRIINITSIVGVTGNPGQANYCASKAGLIGFSKSLAQEIASRNVTVNCI 181 Query: 188 APGAILTDALKSVITPEIEQK----MLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQI 243 APG I +S +T ++ +K ++ + P++R+G DIA A ++L S A++V+GQ Sbjct: 182 APGFI-----ESAMTGKLNEKQKDAIMGNIPMKRMGVGADIAAAVVYLASDEAAYVTGQT 236 Query: 244 LTVSGG 249 L V+GG Sbjct: 237 LHVNGG 242 >3V2G-A nrPDB Length = 271 Score = 107 bits (267), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 84/250 (33%), Positives = 125/250 (50%), Gaps = 13/250 (5%) Query: 6 NLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINA-DAANHVVDEIQQLGGQAFA 64 ++ L GK A +TG GIG IA A GA+V ++ +NA + A VV EI+Q GG+A A Sbjct: 26 SISLAGKTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQAGGRAVA 85 Query: 65 CRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFF 123 R D + + + LG +DILVN+AG P + +ADF +N + F Sbjct: 86 IRADNRDAEAIEQAIRETVEALGGLDILVNSAGIWHSAPLEETTVADFDEVMAVNFRAPF 145 Query: 124 HLSQLVAPEMEKNGGGVILTITSMAAENKNI-NMTSYASSKAAASHLVRNMAFDLGEKNI 182 + + GG I+TI S AE ++ Y++SKAA + L + +A DLG + I Sbjct: 146 --VAIRSASRHLGDGGRIITIGSNLAELVPWPGISLYSASKAALAGLTKGLARDLGPRGI 203 Query: 183 RVNGIAPGAILTDALKSVITP---EIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 VN + PG+ TD + P + + + G+PQDIA +L P +V Sbjct: 204 TVNIVHPGSTDTD-----MNPADGDHAEAQRERIATGSYGEPQDIAGLVAWLAGPQGKFV 258 Query: 240 SGQILTVSGG 249 +G LT+ GG Sbjct: 259 TGASLTIDGG 268 >5CDY-A nrPDB Length = 244 Score = 106 bits (265), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 81/245 (33%), Positives = 125/245 (51%), Gaps = 7/245 (2%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 + +GK A++TGA GIG+ IA GA V+ + + A + + + G Sbjct: 1 MSFEGKIALVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGKGLMLNV 60 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD--FRRAYELNVFSFFH 124 D TS + A ++ G+VDILVNNAG M M D ++ + N+ S F Sbjct: 61 VDPTSIDTVLATIR---AEFGEVDILVNNAGITRDNLL-MRMKDDEWQDIIDTNLTSVFR 116 Query: 125 LSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 LS+ V M K G I+TI S+ N +YA++KA +++A ++ + I V Sbjct: 117 LSKAVMRAMMKKRFGRIITIGSVVGTMGNAGQVNYAAAKAGVIGFSKSLAREVASRGITV 176 Query: 185 NGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQIL 244 N +APG I TD ++ +T + +L P RLG ++IA+A FL S AS++SG+ L Sbjct: 177 NVVAPGFIETDMTRT-LTDDQRAGILAQVPANRLGDAKEIASAVAFLASDEASYISGETL 235 Query: 245 TVSGG 249 V+GG Sbjct: 236 HVNGG 240 >5ITV-A nrPDB Length = 255 Score = 106 bits (265), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 75/251 (29%), Positives = 125/251 (49%), Gaps = 10/251 (3%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 + L K +ITG +GIG F A+VVV+DI+ +V ++ + + Sbjct: 3 MNLTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVR--KENNDRLHFVQ 60 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHL 125 DIT E + A+ G +D+L+NNAG P +M ++D+ + ++N+ F + Sbjct: 61 TDITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLM 120 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 S+ M G G I+ S+ ++ +Y +SK L ++MA D + IRVN Sbjct: 121 SKHALKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIRVN 180 Query: 186 GIAPGAILTDA-LKSVIT------PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASW 238 + PG I T KS + EI+++ + P+ RLG+P++IAN LFL S +S+ Sbjct: 181 CVCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRLGKPEEIANVMLFLASDLSSY 240 Query: 239 VSGQILTVSGG 249 ++G +T GG Sbjct: 241 MTGSAITADGG 251 >4HP8-A nrPDB Length = 247 Score = 106 bits (265), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 83/244 (34%), Positives = 124/244 (50%), Gaps = 10/244 (4%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 L+G+ A++TGA G+G+ IA+ A AGA VV + A + +D I + GG A A D Sbjct: 7 LEGRKALVTGANTGLGQAIAVGLAAAGAEVVCAARRA--PDETLDIIAKDGGNASALLID 64 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAGG-GGPKPFDMPMADFRRAYELNVFSFFHLSQ 127 L+A F + DILVNNAG + D+ ++N+ + F +Q Sbjct: 65 FA--DPLAAKDSFTDAGF---DILVNNAGIIRRADSVEFSELDWDEVMDVNLKALFFTTQ 119 Query: 128 LVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNG 186 A E+ G G ++ I S+ + I + SY ++K + L + +A + K I VN Sbjct: 120 AFAKELLAKGRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTKLLANEWAAKGINVNA 179 Query: 187 IAPGAILTDALKSVITPEIEQK-MLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILT 245 IAPG I T+ +++ K +L+ P R G +DIA AA+FL S AA +V G IL Sbjct: 180 IAPGYIETNNTEALRADAARNKAILERIPAGRWGHSEDIAGAAVFLSSAAADYVHGAILN 239 Query: 246 VSGG 249 V GG Sbjct: 240 VDGG 243 >4KMS-A nrPDB Length = 249 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 78/239 (32%), Positives = 123/239 (51%), Gaps = 9/239 (3%) Query: 14 AIITGAGAGIGKEIAITFATAGASVVVSDI-NADAANHVVDEIQQLGGQAFACRCDITSE 72 AI+TG GIGK A+ G +VV + N DAA E+++ G C E Sbjct: 13 AIVTGGTRGIGKATALELKNKGLTVVANFFSNYDAA----KEMEEKYGIKTKCWNVADFE 68 Query: 73 QELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFHLSQLVAP 131 + A+ + V ILVNNAG K M D+ +N+ S F++S V Sbjct: 69 ECRQAVKEIEEEFKKPVSILVNNAGITKDKMLHRMSHQDWNDVINVNLNSCFNMSSSVME 128 Query: 132 EMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPGA 191 +M G I+ I+S+ A+ + T+Y+++KA + +A + KNI VN IAPG Sbjct: 129 QMRNQDYGRIVNISSINAQAGQVGQTNYSAAKAGIIGFTKALARETASKNITVNCIAPGY 188 Query: 192 ILTDALKSVITPE-IEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 I T+ + +V PE + K++ P +RLGQP++IA A FL A +++G+ ++++GG Sbjct: 189 IATEMVGAV--PEDVLAKIINSIPKKRLGQPEEIARAVAFLVDENAGFITGETISINGG 245 >5JS6-A nrPDB Length = 274 Score = 105 bits (262), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 72/227 (31%), Positives = 117/227 (51%), Gaps = 15/227 (6%) Query: 31 FATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQELSALADFAISKLGKVD 90 F +GA VV+ D + + Q+L G F CD+T E ++ L I + G++D Sbjct: 31 FVNSGARVVICDKDESGGRALE---QELPGAVFIL-CDVTQEDDVKTLVSETIRRFGRLD 86 Query: 91 ILVNNAGGGGP--KPFDMPMADFRRAYELNVFSFFHLSQLVAPEMEKNGGGVILTITSMA 148 +VNNAG P +P + FR+ ELN+ + L++L P + K+ G VI I+S+ Sbjct: 87 CVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNVI-NISSLV 145 Query: 149 AENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSV--ITPE-- 204 Y ++K A + + + +A D +RVN I+PG I T + + + P+ Sbjct: 146 GAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPR 205 Query: 205 --IEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 I + ML P+ R+GQP ++ AA+FL S A++ +G L V+GG Sbjct: 206 ATIREGMLAQ-PLGRMGQPAEVGAAAVFLAS-EANFCTGIELLVTGG 250 >3AUT-A nrPDB Length = 269 Score = 105 bits (261), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 68/245 (27%), Positives = 125/245 (51%), Gaps = 4/245 (1%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN-ADAANHVVDEIQQLGGQAFACRC 67 L K +ITG G+G+ +A+ F A VV++ N + A E+++ GGQA + Sbjct: 13 LKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQAIIVQG 72 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKP-FDMPMADFRRAYELNVF-SFFHL 125 D+T E+++ L AI + G +D+++NNAG P P ++ + ++ + + N+ +F Sbjct: 73 DVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGAFLGS 132 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 + + +E + G ++ ++S+ YA+SK + +A + K IRVN Sbjct: 133 REAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVN 192 Query: 186 GIAPGAILTDALKSVITPEIEQKMLQHT-PIRRLGQPQDIANAALFLCSPAASWVSGQIL 244 I PGA+ T +++ ++ P+ +G+P+++A A FL S AS+V+G L Sbjct: 193 NIGPGAMNTPINAEKFADPVQRADVESMIPMGYIGKPEEVAAVAAFLASSQASYVTGITL 252 Query: 245 TVSGG 249 GG Sbjct: 253 FADGG 257 >1HXH-A nrPDB Length = 253 Score = 105 bits (261), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 79/244 (32%), Positives = 124/244 (50%), Gaps = 11/244 (4%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 RL GK A++TG +G+G E+ GA V SDIN A + E LG ++ R Sbjct: 3 RLQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAE---LGERSMFVRH 59 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDM-PMADFRRAYELNVFSFFHLS 126 D++SE + + + +LG +++LVNNAG P + + DF R ++N S F Sbjct: 60 DVSSEADWTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRLEDFSRLLKINTESVFIGC 119 Query: 127 QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKN--IRV 184 Q M++ GG +I + S+++ Y++SKAA S L R A ++ IRV Sbjct: 120 QQGIAAMKETGGSII-NMASVSSWLPIEQYAGYSASKAAVSALTRAAALSCRKQGYAIRV 178 Query: 185 NGIAPGAILTDALKSVITPEIEQKMLQHTP-IRRLGQ---PQDIANAALFLCSPAASWVS 240 N I P I T +++ + + ++M+ H P + R G+ P+ IA LFL S +S +S Sbjct: 179 NSIHPDGIYTPMMQASLPKGVSKEMVLHDPKLNRAGRAYMPERIAQLVLFLASDESSVMS 238 Query: 241 GQIL 244 G L Sbjct: 239 GSEL 242 >2CFC-A nrPDB Length = 250 Score = 104 bits (259), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 73/247 (29%), Positives = 119/247 (48%), Gaps = 14/247 (5%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFA-----CR 66 + AI+TGA +G G IA F G V D++A+ ++E + A+A R Sbjct: 3 RVAIVTGASSGNGLAIATRFLARGDRVAALDLSAE----TLEETARTHWHAYADKVLRVR 58 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKP----FDMPMADFRRAYELNVFSF 122 D+ E +++A + + G +D+LVNNAG G P+ F + +NV Sbjct: 59 ADVADEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVRGI 118 Query: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182 F + V P M G GVI+ I S+A+ ++Y +SK A L +++A D I Sbjct: 119 FLGCRAVLPHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDYAGSGI 178 Query: 183 RVNGIAPGAILTDALKSVI-TPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSG 241 R N + PG I T + + PE+ ++L P + +G +A+A +FL A++V+G Sbjct: 179 RCNAVCPGMIETPMTQWRLDQPELRDQVLARIPQKEIGTAAQVADAVMFLAGEDATYVNG 238 Query: 242 QILTVSG 248 L + G Sbjct: 239 AALVMDG 245 >4RZI-B nrPDB Length = 240 Score = 103 bits (258), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 72/245 (29%), Positives = 124/245 (50%), Gaps = 13/245 (5%) Query: 6 NLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFAC 65 +L L+ K ++TG GIG I GA V +D+ D N +A Sbjct: 3 SLGLEDKVIVVTGGNRGIGAAIVKLLQEMGAKVAFTDLATDGGNT----------EALGV 52 Query: 66 RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFH 124 ++T + ++A A KLG V +V NAG F + AD+ +N+ + Sbjct: 53 VANVTDLESMTAAAAEITDKLGPVYGVVANAGITKDNFFPKLTPADWDAVLNVNLKGVAY 112 Query: 125 LSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 + M + G I+ I+S++ E N+ T+Y+++KA +++++A + +R Sbjct: 113 SIKPFIEGMYERKAGSIVAISSISGERGNVGQTNYSATKAGVIGMMKSLAREGARYGVRA 172 Query: 185 NGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSP-AASWVSGQI 243 N +APG I T+ + I +I +K+ + P RR G+P++IA A FL SP A+S+V+G++ Sbjct: 173 NAVAPGFIDTE-MTLAIREDIREKITKEIPFRRFGKPEEIAWAVAFLLSPVASSYVTGEV 231 Query: 244 LTVSG 248 L V+G Sbjct: 232 LRVNG 236 >3V2H-A nrPDB Length = 281 Score = 103 bits (257), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 76/252 (30%), Positives = 124/252 (49%), Gaps = 14/252 (5%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINA-DAANHVVDEIQQL-GGQAFACRCDI 69 K A+ITG+ +GIG IA T A AGA++V++ A D V DE+ L G D+ Sbjct: 26 KTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAGLSSGTVLHHPADM 85 Query: 70 TSEQELSALADFAISKLGKVDILVNNAG-GGGPKPFDMPMADFRRAYELNVFSFFHLSQL 128 T E++ + + G DILVNNAG K D P+ + R +N+ S FH + Sbjct: 86 TKPSEIADMMAMVADRFGGADILVNNAGVQFVEKIEDFPVEQWDRIIAVNLSSSFHTIRG 145 Query: 129 VAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIA 188 P M+K G G I+ I S + ++Y ++K L + +A ++ E + VN I Sbjct: 146 AIPPMKKKGWGRIINIASAHGLVASPFKSAYVAAKHGIMGLTKTVALEVAESGVTVNSIC 205 Query: 189 PGAILTDALKSVITPE-----------IEQKMLQHTPIRRLGQPQDIANAALFLCSPAAS 237 PG +LT ++ I + I + ML+ P ++ + +A+ AL+L A+ Sbjct: 206 PGYVLTPLVEKQIPDQARTRGITEEQVINEVMLKGQPTKKFITVEQVASLALYLAGDDAA 265 Query: 238 WVSGQILTVSGG 249 ++G +++ GG Sbjct: 266 QITGTHVSMDGG 277 >3F9I-A nrPDB Length = 249 Score = 103 bits (257), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 72/242 (29%), Positives = 127/242 (52%), Gaps = 9/242 (3%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 L GK ++ITGA +GIG IA G+ V++S N + + + ++ C+ Sbjct: 12 LTGKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKD---NYTIEVCN 68 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAG-GGGPKPFDMPMADFRRAYELNVFSFFHLSQ 127 + +++E S L ISK +DILV NAG M DF + ++N+ + F L++ Sbjct: 69 LANKEECSNL----ISKTSNLDILVCNAGITSDTLAIRMKDQDFDKVIDINLKANFILNR 124 Query: 128 LVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGI 187 +M + G I+ I+S+ N +Y +SKA + +++++++ + I VN + Sbjct: 125 EAIKKMIQKRYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYEVATRGITVNAV 184 Query: 188 APGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVS 247 APG I +D + + + + ++Q P+ G P+D+A A FL S AS+++GQ L V+ Sbjct: 185 APGFIKSD-MTDKLNEKQREAIVQKIPLGTYGIPEDVAYAVAFLASNNASYITGQTLHVN 243 Query: 248 GG 249 GG Sbjct: 244 GG 245 >3WTC-A nrPDB Length = 262 Score = 103 bits (257), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 80/257 (31%), Positives = 125/257 (48%), Gaps = 14/257 (5%) Query: 6 NLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFAC 65 ++ L GK A +TGA GIGK IA+ A GA V++ D+ D E++ LG +A A Sbjct: 3 HMSLSGKIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEALGRRAVAL 62 Query: 66 RCDITSEQEL-SALADFAISKLGKVDILVNNAGGGGPKP-FDMPMADFRRAYELNVFSFF 123 DI++ + S LAD A LG +DI+VNNAG KP D+ A+ + + +NV Sbjct: 63 TADISNRDQFRSTLAD-AAKTLGGLDIMVNNAGICQVKPILDIEPAEIEKIFSINVQGVL 121 Query: 124 HLSQLVAPEM-EKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182 Q A EK G I+ S+A + +Y+++K A L ++ A +L I Sbjct: 122 WGMQAAATLFKEKGTKGKIINACSIAGHEGYPLLGAYSATKFAVRALTQSAAKELASSGI 181 Query: 183 RVNGIAPGAILTDA-------LKSVITPEI---EQKMLQHTPIRRLGQPQDIANAALFLC 232 VN PG + TD + + EI +K ++ + R+ D+A +L Sbjct: 182 TVNSYCPGIVGTDMWVTIDKRMAEITGTEIGATYKKYVEGIALGRVETADDVAGFVAYLS 241 Query: 233 SPAASWVSGQILTVSGG 249 S A +++GQ + + GG Sbjct: 242 SSDADYMTGQSVLIDGG 258 >3T7C-A nrPDB Length = 299 Score = 102 bits (255), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 77/275 (28%), Positives = 133/275 (48%), Gaps = 33/275 (12%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDI------------NADAANHVVDEI 55 +++GK A ITGA G G+ AIT A GA ++ D+ D V ++ Sbjct: 25 KVEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETVRQV 84 Query: 56 QQLGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAG--GGGPKPFDMPMADFRR 113 + LG + A + D+ + A D +++LG++DI++ NA G + M +R Sbjct: 85 EALGRRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRMDPKTWRD 144 Query: 114 AYELNVFSFFHLSQLVAPEME--KNGGGVILTITSMAAENKNINMTSYASSKAAASHLVR 171 ++N+ + +++ P + K GG ++ T +S+ N+ +Y +SK L+R Sbjct: 145 MIDVNLNGAWITARVAIPHIMAGKRGGSIVFT-SSIGGLRGAENIGNYIASKHGLHGLMR 203 Query: 172 NMAFDLGEKNIRVNGIAPGAILTDAL-----KSVITPEIE----------QKMLQHTPIR 216 MA +LG +NIRVN + P ++ T L + P++E + + PI Sbjct: 204 TMALELGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFQVASRQMHVLPIP 263 Query: 217 RLGQPQDIANAALFLCSPAASWVSGQILTVSGGGV 251 + +P DI+NA LFL S A +++G L V GG + Sbjct: 264 YV-EPADISNAILFLVSDDARYITGVSLPVDGGAL 297 >1YXM-A nrPDB Length = 303 Score = 102 bits (255), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 69/250 (27%), Positives = 123/250 (49%), Gaps = 10/250 (4%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQ-----QLGGQAF 63 L G+ AI+TG GIGK I G++VV++ + DE+Q + Sbjct: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 Query: 64 ACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSF 122 +C+I +E+E++ L + GK++ LVNN GG P + + + E N+ Sbjct: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 Query: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182 F++ + V K GG I+ I + + S +++A +L +++A + I Sbjct: 136 FYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHS-GAARAGVYNLTKSLALEWACSGI 194 Query: 183 RVNGIAPGAILTD-ALKSV--ITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 R+N +APG I + A+++ + Q P +R+G P+++++ FL SPAAS++ Sbjct: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254 Query: 240 SGQILTVSGG 249 +GQ + V GG Sbjct: 255 TGQSVDVDGG 264 >4DBZ-A nrPDB Length = 281 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 77/256 (30%), Positives = 117/256 (45%), Gaps = 19/256 (7%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDI 69 D + A++TGA +GIG EIA G V V + + E+++ G +A CD+ Sbjct: 25 DSEVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGVEADGRTCDV 84 Query: 70 TSEQELSALADFAISKLGKVDILVNNAG--GGGPKPFDMPMAD--FRRAYELNVFSFFHL 125 S E+ AL + + G VD+LVNNAG GGG +AD + E N+ F + Sbjct: 85 RSVPEIEALVAAVVERYGPVDVLVNNAGRPGGGAT---AELADELWLDVVETNLTGVFRV 141 Query: 126 SQ--LVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIR 183 ++ L A M + G G I+ I S + ++ Y++SK + + +L I Sbjct: 142 TKQVLKAGGMLERGTGRIVNIASTGGKQGLVHAAPYSASKHGVVGFTKALGLELARTGIT 201 Query: 184 VNGIAPGAILTDALKS----------VITPEIEQKMLQHTPIRRLGQPQDIANAALFLCS 233 VN + PG + T S V T E ++ PI R QP ++A +L Sbjct: 202 VNAVCPGFVETPMAASVREHYSDIWEVSTEEAFDRITARVPIGRYVQPSEVAEMVAYLIG 261 Query: 234 PAASWVSGQILTVSGG 249 P A+ V+ Q L V GG Sbjct: 262 PGAAAVTAQALNVCGG 277 >3GRP-A nrPDB Length = 266 Score = 101 bits (252), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 74/248 (29%), Positives = 128/248 (51%), Gaps = 13/248 (5%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 +L G+ A++TGA GIG+ IA F GA V + D + + LG F Sbjct: 23 FKLTGRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAAD---LGKDVFVFS 79 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHL 125 +++ + + LA+ A ++ +DILVNNAG F M D+ +N+ + L Sbjct: 80 ANLSDRKSIKQLAEVAEREMEGIDILVNNAGITRDGLFVRMQDQDWDDVLAVNLTAASTL 139 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 ++ + M + G I+ ITS+ N T+Y ++KA + +A ++ +NI VN Sbjct: 140 TRELIHSMMRRRYGRIINITSIVGVVGNPGQTNYCAAKAGLIGFSKALAQEIASRNITVN 199 Query: 186 GIAPGAILTDALKSVITPEIEQK----MLQHTPIRRLGQPQDIANAALFLCSPAASWVSG 241 IAPG I KS +T ++ +K ++ P++R+G ++IA A ++L S A++++G Sbjct: 200 CIAPGFI-----KSAMTDKLNEKQKEAIMAMIPMKRMGIGEEIAFATVYLASDEAAYLTG 254 Query: 242 QILTVSGG 249 Q L ++GG Sbjct: 255 QTLHINGG 262 >3D3W-A nrPDB Length = 244 Score = 101 bits (252), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 76/248 (30%), Positives = 123/248 (49%), Gaps = 13/248 (5%) Query: 6 NLRLDGKCAIITGAGAGIGKEIAITFATAGASVV-VSDINADAANHVVDEIQQLGGQAFA 64 L L G+ ++TGAG GIG+ GA VV VS AD + V ++ G Sbjct: 2 ELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLV----RECPGIEPV 57 Query: 65 CRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFF 123 C D+ + + A+ +G VD+LVNNA +PF ++ F R++E+N+ + Sbjct: 58 C-VDLGDWEA----TERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVI 112 Query: 124 HLSQLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182 +SQ+VA + G G I+ ++S ++ N + Y S+K A L + MA +LG I Sbjct: 113 QVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKI 172 Query: 183 RVNGIAPGAILTDALKSVIT-PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSG 241 RVN + P ++T ++ + P + ML P+ + + + + NA LFL S + +G Sbjct: 173 RVNAVNPTVVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTG 232 Query: 242 QILTVSGG 249 L V GG Sbjct: 233 STLPVEGG 240 >5O3Z-A nrPDB Length = 263 Score = 101 bits (251), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 73/255 (28%), Positives = 124/255 (48%), Gaps = 15/255 (5%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQL--GGQAFACRCDI 69 + A++ G G +G + A AG V V+D+N AN + D I G+A+ + D Sbjct: 7 QVAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTINSRYGAGRAYGFKVDA 66 Query: 70 TSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQL 128 T E + ALA G+ D+LV +AG P + DF + ++N+ +F S+ Sbjct: 67 TDEASVEALARAVDETFGRADLLVYSAGVAKAAPITQFRLTDFDLSLQVNLVGYFLCSRE 126 Query: 129 VAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGI 187 + M ++G G I+ I S + + + + + Y+++K L +++A DL E I V+ + Sbjct: 127 FSKLMIRDGIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDLAEYGITVHSL 186 Query: 188 APGAILTDAL----------KSVITPE-IEQKMLQHTPIRRLGQPQDIANAALFLCSPAA 236 G +L + K ITPE +E + P++R QD+ N LF S A Sbjct: 187 MLGNLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPLKRGCDYQDVLNVLLFYASDKA 246 Query: 237 SWVSGQILTVSGGGV 251 ++ +GQ + V+GG V Sbjct: 247 AYCTGQSINVTGGQV 261 >3UN1-A nrPDB Length = 260 Score = 101 bits (251), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 73/253 (28%), Positives = 123/253 (48%), Gaps = 20/253 (7%) Query: 1 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG 60 ++ +R K +ITGA GIG + + VV + + + +I + G Sbjct: 18 LYFQSMMRNQQKVVVITGASQGIGAGLVRAYRDRNYRVVATSRSIKPSAD--PDIHTVAG 75 Query: 61 QAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNV 119 DI+ + + I + G++D LVNNAG KPF +M D+ +NV Sbjct: 76 -------DISKPETADRIVREGIERFGRIDSLVNNAGVFLAKPFVEMTQEDYDHNLGVNV 128 Query: 120 FSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASS--KAAASHLVRNMAFDL 177 FFH++Q A EM K G G I++IT+ + + M S +S K + + R++A + Sbjct: 129 AGFFHITQRAAAEMLKQGSGHIVSITTSLVDQPMVGMPSALASLTKGGLNAVTRSLAMEF 188 Query: 178 GEKNIRVNGIAPGAILTDALKSVITP-EIEQKMLQHTPIRRLGQPQDIANAALFLCSPAA 236 +RVN ++PG I K+ + P E + P+ R+G+ +D+ +A L+L A Sbjct: 189 SRSGVRVNAVSPGVI-----KTPMHPAETHSTLAGLHPVGRMGEIRDVVDAVLYL--EHA 241 Query: 237 SWVSGQILTVSGG 249 +++G+IL V GG Sbjct: 242 GFITGEILHVDGG 254 >5B1Y-A nrPDB Length = 270 Score = 100 bits (250), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 69/249 (27%), Positives = 133/249 (53%), Gaps = 10/249 (4%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVS-DINADAANHVVDEIQQLGG-QAFACR 66 ++ A++TG GIG+ + FA G SVV++ AD A +E ++LG +A+ R Sbjct: 21 METTYALVTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAEEARRLGSPEAYTVR 80 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGG---GGPKPFDMPMADFRRAYELNVFSFF 123 D+ ++ ++ + +++LVN AG GG + + ++++ +N+ + Sbjct: 81 VDVGDPDSVTEMSSRVGELIPHLNVLVNAAGVLQLGGIE--ETSISEWEETLRVNLTGVY 138 Query: 124 HLSQLVAPEMEKNGGGVILTITSMAAENKNINM-TSYASSKAAASHLVRNMAFDLGEKNI 182 +++L+ P + K I+ + S+A E N+ +Y++SKA L + +A L I Sbjct: 139 LVTKLLLPLLRKAKWASIVNVASIAGETGNVVAGVAYSASKAGVIGLTKRLAVQLAGYGI 198 Query: 183 RVNGIAPGAILTDALKSVI-TPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASW-VS 240 RVN +AP + TD +S + TPE +++ P++ + +P+D+A A LFL P S ++ Sbjct: 199 RVNAVAPSFVETDMTRSFLDTPEKRERIASLHPLKIILKPEDVAEAILFLADPRRSRGIT 258 Query: 241 GQILTVSGG 249 G +L+++ G Sbjct: 259 GHVLSINAG 267 >3OEC-A nrPDB Length = 317 Score = 100 bits (250), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 80/274 (29%), Positives = 128/274 (46%), Gaps = 36/274 (13%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDI-----NADAANHVVDE-------I 55 RL GK A ITGA G G+ A+ A GA +V D+ N D A +E + Sbjct: 43 RLQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKETVRLV 102 Query: 56 QQLGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAG----GGGPKPFDMPMADF 111 ++ G + A + D+ L A+ D A+++ G +DILV+N G G D +D Sbjct: 103 EEQGRRIIARQADVRDLASLQAVVDEALAEFGHIDILVSNVGISNQGEVVSLTDQQWSDI 162 Query: 112 RRAYELNVFSFFHLSQLVAPEM-EKNGGGVILTITSMAAENKNINMTSYASSKAAASHLV 170 + N+ +H + V P M E+ GG ++ ++S + YA+SK L+ Sbjct: 163 ---LQTNLIGAWHACRAVLPSMIERGQGGSVIFVSSTVGLRGAPGQSHYAASKHGVQGLM 219 Query: 171 RNMAFDLGEKNIRVNGIAPGAI-----LTDALKSVITPEIEQ----------KMLQHTPI 215 ++A ++G NIRVN + PGA+ L + L + P +E L PI Sbjct: 220 LSLANEVGRHNIRVNSVNPGAVNTEMALNEKLLKMFLPHLENPTREDAAELFSQLTLLPI 279 Query: 216 RRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 + +P+D++NA +L S A ++ G + V GG Sbjct: 280 PWV-EPEDVSNAVAWLASDEARYIHGAAIPVDGG 312 >2HSD-A nrPDB Length = 253 Score = 100 bits (249), Expect = 7e-22, Method: Compositional matrix adjust. Identities = 84/247 (34%), Positives = 120/247 (48%), Gaps = 15/247 (6%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDE-----IQQLGGQAF 63 L GK IITG G+G E A AGA VV++D V+DE ++LG A Sbjct: 3 LSGKTVIITGGARGLGAEAARQAVAAGARVVLAD--------VLDEEGAATARELGDAAR 54 Query: 64 ACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD-FRRAYELNVFSF 122 D+T E++ + +A + G VD LVNNAG + + FR+ E+N+ Sbjct: 55 YQHLDVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVEINLTGV 114 Query: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182 F + V P M+ GGG I+ I+S A +SY +SK L + A +LG I Sbjct: 115 FIGMKTVIPAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRI 174 Query: 183 RVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQ 242 RVN + PG T + E +TP+ R+G+P +IA A + L S +S+V+G Sbjct: 175 RVNSVHPGMTYTPMTAETGIRQGEGN-YPNTPMGRVGEPGEIAGAVVKLLSDTSSYVTGA 233 Query: 243 ILTVSGG 249 L V GG Sbjct: 234 ELAVDGG 240 >5VT6-A nrPDB Length = 269 Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 68/242 (28%), Positives = 122/242 (50%), Gaps = 6/242 (2%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEI--QQLGGQAF-ACRCD 68 + A +TG G+G I+ AG +V VS +++ +HV + ++ G+ F A D Sbjct: 26 RVAFVTGGMGGLGAAISRRLHDAGMAVAVS--HSERNDHVSTWLMHERDAGRDFKAYAVD 83 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQ 127 + + A+ ++ GKVD+L+NNAG F M D+ ++ + F++++ Sbjct: 84 VADFESCERCAEKVLADFGKVDVLINNAGITRDATFMKMTKGDWDAVMRTDLDAMFNVTK 143 Query: 128 LVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGI 187 M + G I+ I S+ +YAS+KA + +A + ++ I VN + Sbjct: 144 QFIAGMVERRFGRIVNIGSVNGSRGAFGQANYASAKAGIHGFTKTLALETAKRGITVNTV 203 Query: 188 APGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVS 247 +PG + T +++V +E K+L P+ RLG+P ++A FLCS A +V+G L ++ Sbjct: 204 SPGYLATAMVEAVPQDVLEAKILPQIPVGRLGRPDEVAALIAFLCSDDAGFVTGADLAIN 263 Query: 248 GG 249 GG Sbjct: 264 GG 265 >3EZL-A nrPDB Length = 256 Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 65/240 (27%), Positives = 122/240 (50%), Gaps = 3/240 (1%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVS-DINADAANHVVDEIQQLGGQAFACRCDIT 70 + A +TG GIG I G VV N+ +++ + LG +A ++ Sbjct: 14 RIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYASEGNVG 73 Query: 71 SEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQLV 129 D +++G++D+LVNNAG F M D++ + N+ S F++++ V Sbjct: 74 DWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTREDWQAVIDTNLTSLFNVTKQV 133 Query: 130 APEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAP 189 M + G G I+ I+S+ + T+Y+++KA ++A ++ K + VN ++P Sbjct: 134 IDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVATKGVTVNTVSP 193 Query: 190 GAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 G I TD +K+ I P++ +K++ P+RRLG P +I + +L S + + +G +++GG Sbjct: 194 GYIGTDMVKA-IRPDVLEKIVATIPVRRLGSPDEIGSIVAWLASEESGFSTGADFSLNGG 252 >5JY1-A nrPDB Length = 274 Score = 98.6 bits (244), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 75/245 (30%), Positives = 124/245 (50%), Gaps = 4/245 (1%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 L+ + A++TGAG GIG+ +A +F GA+V++++IN V EI+++GG++ + D Sbjct: 12 LEQRVALVTGAGGGIGRGVARSFGNEGAAVIIAEINESTGRQVEQEIREMGGRSLFVKTD 71 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD--FRRAYELNVFSFFHLS 126 +TS+ + A A+ + G +DILVNNA P D + ++++ + Sbjct: 72 VTSKASIEAAVRSAVEQFGSLDILVNNAFVPTPNVLLEEKTDEMLEQTLTTSLWATWWAM 131 Query: 127 QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNG 186 + M + G I+ S+ E Y ++KA L R+ A + G NI VN Sbjct: 132 RAAFVPMRERRWGRIVNFYSIDTETGAWLHGDYNTAKAGIVGLTRSAASEWGRFNITVNA 191 Query: 187 IAPGAILTDALK-SVITPEIEQKMLQHTPIRRLGQP-QDIANAALFLCSPAASWVSGQIL 244 IAP A+ + + PE ++ P+ R G P QDI AA+F S + +V+G+ L Sbjct: 192 IAPTAMGATFFELAAKNPEFAERSAAARPLGRSGDPEQDIGPAAVFFASEMSRFVTGETL 251 Query: 245 TVSGG 249 V GG Sbjct: 252 HVDGG 256 >4CQL-A nrPDB Length = 261 Score = 98.2 bits (243), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 71/252 (28%), Positives = 125/252 (49%), Gaps = 11/252 (4%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLG-------G 60 RL A++TGAG+GIG+ +++ A GA+V D++ AA V + G G Sbjct: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 Query: 61 QAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMA--DFRRAYELN 118 A + D++ + L + + + +V + G F + M+ D+ + +N Sbjct: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 Query: 119 VFSFFHLSQLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDL 177 + F ++Q A + NG G I+ I+S+ + N+ T+YA+SKA L + A +L Sbjct: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 Query: 178 GEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAAS 237 G IR N + PG I T + V ++ K+ + P+ LG P+D+A+ FL S + Sbjct: 188 GRHGIRCNSVLPGFIATPMTQKV-PQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSG 246 Query: 238 WVSGQILTVSGG 249 +++G + V+GG Sbjct: 247 YITGTSVEVTGG 258 >5IZ4-A nrPDB Length = 271 Score = 97.8 bits (242), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 69/250 (27%), Positives = 124/250 (49%), Gaps = 17/250 (6%) Query: 15 IITGAGAGIGKEIAITFATAGASVVV---SDINADAANHVVDEIQQLGGQAFACRCDITS 71 +ITG+ +GIG A+ FA AG SV + D DAA+ V + G Q D+ Sbjct: 18 VITGSASGIGAATALRFAQAGWSVAIGNFDDSTRDAASTVEALCRDAGAQTLIFDADVGK 77 Query: 72 EQELSALADFAISKLGKVDILVNNAGGGGPKP---FD-MPMADFRRAYELNVFSFFHLSQ 127 + + D S+ ++D L+N AG P FD + +F R Y +N+ + +++ Sbjct: 78 DADCRHAVDMVASRWQRIDALINCAGTTRVIPHNAFDQIDDFEFERVYRVNLIGLYQMTR 137 Query: 128 LVAPEMEKNGGGV----ILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIR 183 P + ++ ++ ++S+A N + +YA+SK A + L ++A +L +IR Sbjct: 138 AAVPLLRESASATRSTSVVNVSSLAGLNGTGSSIAYAASKGAVNTLTLSLARNLA-PHIR 196 Query: 184 VNGIAPGAI----LTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 VN +APG + L L + + +M + P++R+ +P +IA A FL + A + + Sbjct: 197 VNALAPGMVDDGLLLRVLDAAAYDGVLSRMTESAPLKRVSRPAEIAELAWFLTAHAPA-I 255 Query: 240 SGQILTVSGG 249 +GQ++ G Sbjct: 256 TGQVIAAENG 265 >2Q2Q-A nrPDB Length = 255 Score = 97.8 bits (242), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 76/256 (29%), Positives = 118/256 (46%), Gaps = 13/256 (5%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 L GK A++TG+ +GIG IA A AGA++V++ A + EI + G +A D Sbjct: 2 LKGKTALVTGSTSGIGLGIAQVLARAGANIVLNGFGDPAP--ALAEIARHGVKAVHHPAD 59 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFHLSQ 127 ++ ++ AL A + G VDILVNNAG P + P+ + + LN+ + FH ++ Sbjct: 60 LSDVAQIEALFALAEREFGGVDILVNNAGIQHVAPVEQFPLESWDKIIALNLSAVFHGTR 119 Query: 128 LVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGI 187 L P M G I+ I S+ + +Y ++K L + + + N+ N I Sbjct: 120 LALPGMRARNWGRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGLETATSNVTCNAI 179 Query: 188 APGAILTDALKSVI--------TPEIEQKML--QHTPIRRLGQPQDIANAALFLCSPAAS 237 PG +LT ++ I P Q L + P P+ + LFLCS A S Sbjct: 180 CPGWVLTPLVQKQIDDRAANGGDPLQAQHDLLAEKQPSLAFVTPEHLGELVLFLCSEAGS 239 Query: 238 WVSGQILTVSGGGVQE 253 V G V GG + + Sbjct: 240 QVRGAAWNVDGGWLAQ 255 >3VZS-A nrPDB Length = 257 Score = 97.8 bits (242), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 67/240 (27%), Positives = 120/240 (50%), Gaps = 3/240 (1%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVS-DINADAANHVVDEIQQLGGQAFACRCDIT 70 + A +TG GIG I A G VV N+ +++ + LG A ++ Sbjct: 15 RIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGNVA 74 Query: 71 SEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQLV 129 D S++G+VD+L+NNAG F M AD+ + N+ S F++++ V Sbjct: 75 DWDSTKTAFDKVKSEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNVTKQV 134 Query: 130 APEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAP 189 M G G I+ I+S+ + T+Y+++KA +A ++ K + VN ++P Sbjct: 135 IDGMADRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNTVSP 194 Query: 190 GAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 G I TD +K+ I ++ K++ P++RLG P++IA+ +L S + + +G +++GG Sbjct: 195 GYIATDMVKA-IRQDVLDKIVATIPVKRLGLPEEIASICAWLSSEESGFSTGADFSLNGG 253 >2FWM-X nrPDB Length = 250 Score = 97.1 bits (240), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 71/255 (27%), Positives = 125/255 (49%), Gaps = 22/255 (8%) Query: 6 NLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFAC 65 ++ GK +TGAG GIG A+ F AGA V D + FA Sbjct: 2 HMDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQY-----------PFAT 50 Query: 66 RC-DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFF 123 D+ +++ + +++ ++D LVN AG D + D+++ + +NV F Sbjct: 51 EVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAF 110 Query: 124 HLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIR 183 +L Q + + GG I+T+ S AA I M++Y +SKAA L ++ +L +R Sbjct: 111 NLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVR 170 Query: 184 VNGIAPGAILTDALKSV-ITPEIEQKMLQ--------HTPIRRLGQPQDIANAALFLCSP 234 N ++PG+ TD +++ ++ + E++ ++ P+ ++ +PQ+IAN LFL S Sbjct: 171 CNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASD 230 Query: 235 AASWVSGQILTVSGG 249 AS ++ Q + V GG Sbjct: 231 LASHITLQDIVVDGG 245 >3W8F-A nrPDB Length = 260 Score = 96.7 bits (239), Expect = 9e-21, Method: Compositional matrix adjust. Identities = 74/255 (29%), Positives = 117/255 (45%), Gaps = 14/255 (5%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN--ADAANHVVDEIQQLGGQAFACR 66 L GK A++TG+ +GIG +A A AGA VV++ D + G +A+ Sbjct: 2 LKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVKAYYLN 61 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFHL 125 D++ Q A LG +DILVNNAG P + P+ + LN+ + FH Sbjct: 62 ADLSDAQATRDFIAKAAEALGGLDILVNNAGIQHTAPIEEFPVDKWNAIIALNLSAVFHG 121 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 + P M+K G G I+ I S ++N ++Y ++K L + A + K I N Sbjct: 122 TAAALPIMQKQGWGRIINIASAHGLVASVNKSAYVAAKHGVVGLTKVTALENAGKGITCN 181 Query: 186 GIAPGAILTDALKSVITPEIEQK-----------MLQHTPIRRLGQPQDIANAALFLCSP 234 I PG + T ++ I +QK + + P + P+ + AA+FL S Sbjct: 182 AICPGWVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQPSLQFVTPEQLGGAAVFLSSA 241 Query: 235 AASWVSGQILTVSGG 249 AA ++G L++ GG Sbjct: 242 AADQMTGTTLSLDGG 256 >4IS3-A nrPDB Length = 268 Score = 96.7 bits (239), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 73/250 (29%), Positives = 123/250 (49%), Gaps = 5/250 (2%) Query: 2 FNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQL--G 59 F NL D K IITG GIG A F GA V + + + + ++++L Sbjct: 17 FQGMNLVQD-KVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYPE 75 Query: 60 GQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELN 118 + D+TS + A K G++D+++NNAG F + +F+ ++N Sbjct: 76 EEVLGFAPDLTSRDAVMAAVGQVAQKYGRLDVMINNAGITSNNVFSRVSEEEFKHIMDIN 135 Query: 119 VFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLG 178 V F+ + M+ GVI+ S+ +++ Y +SKA+ L + ++ Sbjct: 136 VTGVFNGAWCAYQCMKDAKKGVIINTASVTGIFGSLSGVGYPASKASVIGLTHGLGREII 195 Query: 179 EKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASW 238 KNIRV G+APG + TD + + PEI + L+ P++R+ +P++IAN LFL S AS Sbjct: 196 RKNIRVVGVAPGVVNTD-MTNGNPPEIMEGYLKALPMKRMLEPEEIANVYLFLASDLASG 254 Query: 239 VSGQILTVSG 248 ++ ++V G Sbjct: 255 ITATTVSVDG 264 >2YW9-A nrPDB Length = 261 Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 74/249 (29%), Positives = 123/249 (49%), Gaps = 11/249 (4%) Query: 9 LDGKCAIITGAG--AGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 L GK A++ G +G IA AGA V +S A+ +++ + G A R Sbjct: 6 LSGKKALVMGVTNQRSLGFAIAAKLKEAGAEVALS-YQAERLRPEAEKLAEALGGALLFR 64 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRR-----AYELNVFS 121 D+T ++EL AL G +D LV+ + + D RR A E++ +S Sbjct: 65 ADVTQDEELDALFAGVKEAFGGLDYLVHAIAFAPREAMEGRYIDTRRQDWLLALEVSAYS 124 Query: 122 FFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKN 181 +++ P + + GG I+T+T A+E A +KAA VR +A++LG K Sbjct: 125 LVAVARRAEPLLREGGG--IVTLTYYASEKVVPKYNVMAIAKAALEASVRYLAYELGPKG 182 Query: 182 IRVNGIAPGAILTDALKSVI-TPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVS 240 +RVN I+ G + T A +S+ ++ ++ Q P+RR +++ N LFL SP AS ++ Sbjct: 183 VRVNAISAGPVRTVAARSIPGFTKMYDRVAQTAPLRRNITQEEVGNLGLFLLSPLASGIT 242 Query: 241 GQILTVSGG 249 G+++ V G Sbjct: 243 GEVVYVDAG 251 >2NM0-A nrPDB Length = 253 Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 68/239 (28%), Positives = 112/239 (46%), Gaps = 13/239 (5%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITS 71 + ++TG GIG IA FA AG V ++ + + A +CDIT Sbjct: 22 RSVLVTGGNRGIGLAIARAFADAGDKVAITYRSGEPPEGF-----------LAVKCDITD 70 Query: 72 EQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQLVA 130 +++ G V++L+ NAG + M DF E N+ F + + Sbjct: 71 TEQVEQAYKEIEETHGPVEVLIANAGVTKDQLLMRMSEEDFTSVVETNLTGTFRVVKRAN 130 Query: 131 PEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPG 190 M + G ++ I+S+ + +YA+SKA R++A +LG +NI N +APG Sbjct: 131 RAMLRAKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARSLARELGSRNITFNVVAPG 190 Query: 191 AILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 + TD K V+T E ++ P+ R +P++IA FL S AS+++G ++ V GG Sbjct: 191 FVDTDMTK-VLTDEQRANIVSQVPLGRYARPEEIAATVRFLASDDASYITGAVIPVDGG 248 >1X1T-A nrPDB Length = 260 Score = 95.1 bits (235), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 74/258 (28%), Positives = 124/258 (48%), Gaps = 20/258 (7%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQ-----QLGGQAF 63 L GK A++TG+ +GIG IA A GA +V++ DAA +++++ Q G + Sbjct: 2 LKGKVAVVTGSTSGIGLGIATALAAQGADIVLNGFG-DAAE--IEKVRAGLAAQHGVKVL 58 Query: 64 ACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSF 122 D++ + + L D A+ ++G++DILVNNAG D P + LN+ + Sbjct: 59 YDGADLSKGEAVRGLVDNAVRQMGRIDILVNNAGIQHTALIEDFPTEKWDAILALNLSAV 118 Query: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182 FH + P M+K G G I+ I S + N ++Y ++K + A + + I Sbjct: 119 FHGTAAALPHMKKQGFGRIINIASAHGLVASANKSAYVAAKHGVVGFTKVTALETAGQGI 178 Query: 183 RVNGIAPGAILTDALKSVITPEIEQKML-QHTPIRRL----------GQPQDIANAALFL 231 N I PG + T ++ I+ E+ + Q T R L P+ + A+FL Sbjct: 179 TANAICPGWVRTPLVEKQISALAEKNGVDQETAARELLSEKQPSLQFVTPEQLGGTAVFL 238 Query: 232 CSPAASWVSGQILTVSGG 249 S AA+ ++G ++V GG Sbjct: 239 ASDAAAQITGTTVSVDGG 256 >4CR6-A nrPDB Length = 271 Score = 95.1 bits (235), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 82/253 (32%), Positives = 123/253 (48%), Gaps = 18/253 (7%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 RL GK AI+TGA GIG+ + GASVV D+ A +E A C Sbjct: 12 RLAGKAAIVTGAAGGIGRATVEAYLREGASVVAMDLAPRLAATRYEEPG-----AIPIAC 66 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGG---GGPKPF-DMPMADFRRAYELNVFSFF 123 D+ + A A+++LG +DILV AGG GG F D+ AD+ R ++N+ F Sbjct: 67 DLADRAAIDAAMADAVARLGGLDILV--AGGALKGGTGNFLDLSDADWDRYVDVNMTGTF 124 Query: 124 HLSQLVAPEMEKNGGG------VILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDL 177 + A M G G I+TI S+ + +Y ++K + L R MA DL Sbjct: 125 LTCRAGARAMVAAGAGKDGRSARIITIGSVNSFMAEPEAAAYVAAKGGVAMLTRAMAVDL 184 Query: 178 GEKNIRVNGIAPGAI-LTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAA 236 I VN IAPG + +T P + +++L + R G P+++A AA+FL + Sbjct: 185 ARHGILVNMIAPGPVDVTGNNTGYSEPRLAEQVLDEVALGRPGLPEEVATAAVFLAEDGS 244 Query: 237 SWVSGQILTVSGG 249 S+++G +T+ GG Sbjct: 245 SFITGSTITIDGG 257 >3OML-A nrPDB Length = 613 Score = 94.7 bits (234), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 71/216 (32%), Positives = 110/216 (50%), Gaps = 20/216 (9%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDI---------NADAANHVVDEIQQ 57 LR DG+ A++TGAGAG+G+E A+ FA GA VVV+D+ + AA+ VVDEI++ Sbjct: 15 LRYDGRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRK 74 Query: 58 LGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYE 116 GG+A A D S + + + + AI G+VDILVNNAG + D+ + Sbjct: 75 AGGEAVA---DYNSVIDGAKVIETAIKAFGRVDILVNNAGILRDRSLVKTSEQDWNLVND 131 Query: 117 LNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFD 176 +++ F +Q P M+K G I+ +S + N +Y ++K L +A + Sbjct: 132 VHLKGSFKCTQAAFPYMKKQNYGRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLANTVAIE 191 Query: 177 LGEKNIRVNGIAPGA-------ILTDALKSVITPEI 205 N+ N I P A IL D L + + P++ Sbjct: 192 GARNNVLCNVIVPTAASRMTEGILPDILFNELKPKL 227 >1UZM-A nrPDB Length = 247 Score = 94.4 bits (233), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 70/240 (29%), Positives = 114/240 (47%), Gaps = 15/240 (6%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITS 71 + ++TG GIG IA A G V V+ + A + F D+T Sbjct: 16 RSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPKGL-----------FGVEVDVTD 64 Query: 72 EQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD--FRRAYELNVFSFFHLSQLV 129 + G V++LV+NAG F M M + F + N+ F ++Q Sbjct: 65 SDAVDRAFTAVEEHQGPVEVLVSNAGLSA-DAFLMRMTEEKFEKVINANLTGAFRVAQRA 123 Query: 130 APEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAP 189 + M++N G ++ I S++ N +YA+SKA + R++A +L + N+ N +AP Sbjct: 124 SRSMQRNKFGRMIFIGSVSGLWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAP 183 Query: 190 GAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 G I TD ++ + I+Q LQ P +R+G P ++A FL S AS++SG ++ V GG Sbjct: 184 GYIDTDMTRA-LDERIQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISGAVIPVDGG 242 >1H5Q-A nrPDB Length = 265 Score = 94.0 bits (232), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 78/256 (30%), Positives = 130/256 (50%), Gaps = 27/256 (10%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAF-----ACR 66 K I+TG GIG +A T A A A V+ I AA+ V E+ + G+ F A + Sbjct: 15 KTIIVTGGNRGIG--LAFTRAVAAAGANVAVIYRSAADAV--EVTEKVGKEFGVKTKAYQ 70 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKP-FDMPMADFRRAYELNVFSFFHL 125 CD+++ ++ + LG + L+ NAG KP ++ DF Y++NVF F+ Sbjct: 71 CDVSNTDIVTKTIQQIDADLGPISGLIANAGVSVVKPATELTHEDFAFVYDVNVFGVFNT 130 Query: 126 SQLVAP-EMEKNGGGVILTITSMAAE-------NKNINMTSYASSKAAASHLVRNMAFDL 177 + VA ++K G I+ +SM+++ N ++ Y SSKAA S+LV+ +A + Sbjct: 131 CRAVAKLWLQKQQKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSSKAACSNLVKGLAAEW 190 Query: 178 GEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHT----PIRRLGQPQDIANAALFLCS 233 IRVN ++PG + TD T +++K+ H P+ R QP+++ A+ L S Sbjct: 191 ASAGIRVNALSPGYVNTDQ-----TAHMDKKIRDHQASNIPLNRFAQPEEMTGQAILLLS 245 Query: 234 PAASWVSGQILTVSGG 249 A++++G + GG Sbjct: 246 DHATYMTGGEYFIDGG 261 >3V8B-A nrPDB Length = 283 Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 76/253 (30%), Positives = 120/253 (47%), Gaps = 20/253 (7%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSE 72 A+ITGAG+GIG+ A+ A G +V V DEI GGQA A D++ E Sbjct: 30 VALITGAGSGIGRATALALAADGVTVGALGRTRTEVEEVADEIVGAGGQAIALEADVSDE 89 Query: 73 QELSALADFAISKLGKVDILVNNAG-GGGPKPF-DMPMADFRRAYELNVFSFFHLSQLVA 130 ++ + K G +DI+V NAG G P D+ ++ +N+ F L Sbjct: 90 LQMRNAVRDLVLKFGHLDIVVANAGINGVWAPIDDLKPFEWDETIAVNLRGTFLTLHLTV 149 Query: 131 PEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASH-----LVRNMAFDLGEKNIRVN 185 P +++ GGG I+ ++S+ N T+ ++ A+ +V+ +A +LG+ +IRVN Sbjct: 150 PYLKQRGGGAIVVVSSI---NGTRTFTTPGATAYTATKAAQVAIVQQLALELGKHHIRVN 206 Query: 186 GIAPGAILTDALKSVITPEIEQKMLQ------HTPIRRLGQP---QDIANAALFLCSPAA 236 + PGAI T+ + E+ + PI GQP +D+A FL S A Sbjct: 207 AVCPGAIETNISDNTKLRHEEETAIPVEWPKGQVPITD-GQPGRSEDVAELIRFLVSERA 265 Query: 237 SWVSGQILTVSGG 249 V+G + + GG Sbjct: 266 RHVTGSPVWIDGG 278 >2PH3-A nrPDB Length = 245 Score = 91.7 bits (226), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 75/241 (31%), Positives = 119/241 (49%), Gaps = 4/241 (1%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVS-DINADAANHVVDEIQQLGGQAFACR-CDI 69 + A+ITGA GIG+ IA+ A G ++ + N + A V +E ++ G A ++ Sbjct: 2 RKALITGASRGIGRAIALRLAEDGFALAIHYGQNREKAEEVAEEARRRGSPLVAVLGANL 61 Query: 70 TSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQL 128 + +AL A LG +D LVNNAG M D+ E N+ + F ++ Sbjct: 62 LEAEAATALVHQAAEVLGGLDTLVNNAGITRDTLLVRMKDEDWEAVLEANLSAVFRTTRE 121 Query: 129 VAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIA 188 M K G I+ ITS+ N +Y +SKA R +A + ++ I VN +A Sbjct: 122 AVKLMMKARFGRIVNITSVVGILGNPGQANYVASKAGLIGFTRAVAKEYAQRGITVNAVA 181 Query: 189 PGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSG 248 PG I T+ + + E+++ L+ P R G+P+++A A FL S A +++GQ L V G Sbjct: 182 PGFIETE-MTERLPQEVKEAYLKQIPAGRFGRPEEVAEAVAFLVSEKAGYITGQTLCVDG 240 Query: 249 G 249 G Sbjct: 241 G 241 >3U4C-A nrPDB Length = 281 Score = 91.7 bits (226), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 65/260 (25%), Positives = 120/260 (46%), Gaps = 13/260 (5%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEI--QQLGGQAFAC 65 + + A + GA GIGK IA+ A S+V++ N D V ++I + Sbjct: 20 HMSKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVL 79 Query: 66 RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFH 124 D++ + + + S+ G++D+L+NN GG P FD + D + ++ Sbjct: 80 AGDMSDQHTRAGIFQKIESQCGRLDVLINNIPGGAPDTFDNCNIEDMTATFTQKTVAYID 139 Query: 125 LSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 + + M++N G I+ I + NM + + AA + +N++ L NI V Sbjct: 140 AIKRASSLMKQNEFGRIINIVGNLWKEPGANMFTNSMMNAALINASKNISIQLAPHNITV 199 Query: 185 NGIAPGAILTDALK----------SVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSP 234 N + PG I TD S+ + E+++ P++R+G ++ A A FL S Sbjct: 200 NCLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGIPMKRVGSAEETAALAAFLASE 259 Query: 235 AASWVSGQILTVSGGGVQEL 254 AS+++GQ ++ GG ++ + Sbjct: 260 EASYITGQQISADGGSMKSI 279 >4EGF-A nrPDB Length = 266 Score = 90.5 bits (223), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 87/249 (34%), Positives = 127/249 (51%), Gaps = 8/249 (3%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVS--DINA-DAANHVVDEIQQLGGQAF 63 LRLDGK A+ITGA GIG +IA FA AGA +V+S D++ DAA + E Q G Sbjct: 16 LRLDGKRALITGATKGIGADIARAFAAAGARLVLSGRDVSELDAARRALGE--QFGTDVH 73 Query: 64 ACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKP-FDMPMADFRRAYELNVFSF 122 D+ + LA A G +D+LVNNAG P+P D F +N+ + Sbjct: 74 TVAIDLAEPDAPAELARRAAEAFGGLDVLVNNAGISHPQPVVDTDPQLFDATIAVNLRAP 133 Query: 123 FHLSQLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKN 181 L+ V M G GG I+T+ S AA + +Y +SKA + +A +LG Sbjct: 134 ALLASAVGKAMVAAGEGGAIITVASAAALAPLPDHYAYCTSKAGLVMATKVLARELGPHG 193 Query: 182 IRVNGIAPGAILTDALKSVITPEIEQ-KMLQHTPIRRLGQPQDIANAALFLCSPAASWVS 240 IR N + P +LT+ + V E + M+ P+ R P ++++A ++L S AAS ++ Sbjct: 194 IRANSVCPTVVLTEMGQRVWGDEAKSAPMIARIPLGRFAVPHEVSDAVVWLASDAASMIN 253 Query: 241 GQILTVSGG 249 G + V GG Sbjct: 254 GVDIPVDGG 262 >2P91-A nrPDB Length = 285 Score = 90.1 bits (222), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 67/252 (26%), Positives = 122/252 (48%), Gaps = 16/252 (6%) Query: 9 LDGKCAIITGAG--AGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 L+GK A+ITG I IA +F GA + + V EI + G + Sbjct: 19 LEGKRALITGVANERSIAYGIAKSFHREGAQLAFTYATPKLEKRV-REIAKGFGSDLVVK 77 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-----DMPMADFRRAYELNVFS 121 CD++ ++++ L F G +DI+V++ + F D F+ A +++V+S Sbjct: 78 CDVSLDEDIKNLKKFLEENWGSLDIIVHSIAYAPKEEFKGGVIDTSREGFKIAMDISVYS 137 Query: 122 FFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKN 181 L++ + P ME G ++ T++ AE + +KAA VR +A+D+ + Sbjct: 138 LIALTRELLPLMEGRNGAIV-TLSYYGAEKVVPHYNVMGIAKAALESTVRYLAYDIAKHG 196 Query: 182 IRVNGIAPGAILTDALKSVITPEIEQKMLQH-TPIRRLGQP---QDIANAALFLCSPAAS 237 R+N I+ G + T A S+ + +++H T + G+P +D+ + A+FLCS A Sbjct: 197 HRINAISAGPVKTLAAYSITGFHL---LMEHTTKVNPFGKPITIEDVGDTAVFLCSDWAR 253 Query: 238 WVSGQILTVSGG 249 ++G+++ V G Sbjct: 254 AITGEVVHVDNG 265 >3GDF-A nrPDB Length = 267 Score = 89.7 bits (221), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 69/252 (27%), Positives = 120/252 (47%), Gaps = 9/252 (3%) Query: 5 DNLRLDGKCAIITGAGA--GIGKEIAITFATAGASVVVSDIN-ADAANHVVDEIQQLGG- 60 D L L GK ++TGA G+G E A A GA+V ++ + A A V E+++ G Sbjct: 14 DQLSLKGKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKTYGI 73 Query: 61 QAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKP-FDMPMADFRRAYELNV 119 +A A +C + S + L ++ G++D + NAG D + + ++++ Sbjct: 74 KAKAYKCQVDSYESCEKLVKDVVADFGQIDAFIANAGATADSGILDGSVEAWNHVVQVDL 133 Query: 120 FSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNI--NMTSYASSKAAASHLVRNMAFDL 177 FH ++ V ++ G G ++ SM+ N TSY +KA H+ R++A + Sbjct: 134 NGTFHCAKAVGHHFKERGTGSLVITASMSGHIANFPQEQTSYNVAKAGCIHMARSLANEW 193 Query: 178 GEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAAS 237 RVN I+PG I T L + E +Q P+ R G +++ A ++ S A++ Sbjct: 194 -RDFARVNSISPGYIDT-GLSDFVPKETQQLWHSMIPMGRDGLAKELKGAYVYFASDAST 251 Query: 238 WVSGQILTVSGG 249 + +G L + GG Sbjct: 252 YTTGADLLIDGG 263 >1NFF-A nrPDB Length = 260 Score = 89.7 bits (221), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 69/248 (27%), Positives = 117/248 (47%), Gaps = 10/248 (4%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 RL GK A+++G G+G GA VV DI + + E+ A Sbjct: 4 RLTGKVALVSGGARGMGASHVRAMVAEGAKVVFGDILDEEGKAMAAELAD---AARYVHL 60 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLS 126 D+T + A D A++ G + +LVNNAG D + +++R ++N+ F Sbjct: 61 DVTQPAQWKAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLTGVFLGI 120 Query: 127 QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNG 186 + V M++ G G I+ I+S+ + Y ++K A L ++ A +LG IRVN Sbjct: 121 RAVVKPMKEAGRGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTALELGPSGIRVNS 180 Query: 187 IAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTV 246 I PG + K+ +T + + + Q T + R +P +++N ++L S +S+ +G V Sbjct: 181 IHPGLV-----KTPMTDWVPEDIFQ-TALGRAAEPVEVSNLVVYLASDESSYSTGAEFVV 234 Query: 247 SGGGVQEL 254 GG V L Sbjct: 235 DGGTVAGL 242 >3ZV3-A nrPDB Length = 281 Score = 89.0 bits (219), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 74/259 (28%), Positives = 122/259 (47%), Gaps = 21/259 (8%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 ++L G+ A+ITG +G+G+ + F GA V V D +A+ + E+ GG A Sbjct: 1 MKLTGEVALITGGASGLGRALVDRFVAEGARVAVLDKSAERLREL--EVAH-GGNAVGVV 57 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAG------GGGPKPFDMPMADFRRAYELNVF 120 D+ S Q+ A+ ++ GK+D L+ NAG P D A F + +NV Sbjct: 58 GDVRSLQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDIFHVNVK 117 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 + H + P + + G V+ TI++ A N Y ++K A LVR MAF+L Sbjct: 118 GYIHAVKACLPALVSSRGSVVFTISN-AGFYPNGGGPLYTATKHAVVGLVRQMAFELA-P 175 Query: 181 NIRVNGIAPGAILTD---------ALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFL 231 ++RVNG+APG + TD + +S+ + + + PI R+ ++ A +F Sbjct: 176 HVRVNGVAPGGMNTDLRGPSSLGLSEQSISSVPLADMLKSVLPIGRMPALEEYTGAYVFF 235 Query: 232 CSPAASW-VSGQILTVSGG 249 + S +G +L GG Sbjct: 236 ATRGDSLPATGALLNYDGG 254 >2BGM-A nrPDB Length = 278 Score = 87.4 bits (215), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 66/228 (28%), Positives = 114/228 (50%), Gaps = 11/228 (4%) Query: 31 FATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQELSALADFAISKLGKVD 90 F GA VV++DI D V + I +F CD+T ++++ L D I+K GK+D Sbjct: 36 FVRYGAKVVIADIADDHGQKVCNNIGSPDVISFV-HCDVTKDEDVRNLVDTTIAKHGKLD 94 Query: 91 ILVNNAGGGGPKPFDMPMA---DFRRAYELNVFSFFHLSQLVAPEMEKNGGGVILTITSM 147 I+ N G P+ + A DF+R ++NV+ F +++ A M G I+ S+ Sbjct: 95 IMFGNVGVLSTTPYSILEAGNEDFKRVMDINVYGAFLVAKHAARVMIPAKKGSIVFTASI 154 Query: 148 AAENKNINMTS-YASSKAAASHLVRNMAFDLGEKNIRVNGIAP----GAILTDALKSVIT 202 ++ ++ Y ++K A L ++ +LGE IRVN ++P +LTD V + Sbjct: 155 SSFTAGEGVSHVYTATKHAVLGLTTSLCTELGEYGIRVNCVSPYIVASPLLTDVF-GVDS 213 Query: 203 PEIEQKMLQHTPIR-RLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 +E+ Q ++ L + +D+A+A +L + +VSG L + GG Sbjct: 214 SRVEELAHQAANLKGTLLRAEDVADAVAYLAGDESKYVSGLNLVIDGG 261 >4RGB-A nrPDB Length = 294 Score = 87.0 bits (214), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 75/267 (28%), Positives = 126/267 (47%), Gaps = 26/267 (9%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINAD--------AANHVVDE----IQ 56 LDG+ ITGA G G+ A+ A GA++V DI D ++E ++ Sbjct: 23 LDGRVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEETARLVE 82 Query: 57 QLGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD-FRRAY 115 + G + + D+ + L + D + + G +D ++ NAG P + ++ R Sbjct: 83 KTGQEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLTNPDERDASEALRLGL 142 Query: 116 ELNVFSFFHLSQLVAPEMEKNG-GGVILTITSMAA----ENKNINMTSYASSKAAASHLV 170 ++ + ++ Q+ P M++ G GG ++ +SM A + +Y +SK A + LV Sbjct: 143 DIMLIGVWNTFQVAIPHMKERGQGGNLIATSSMIALLDLTDGRGGTDAYLTSKLAITGLV 202 Query: 171 RNMAFDLGEKNIRVNGIAP----GAILTD--ALKSVI--TPEIEQKMLQHTPIRRLGQPQ 222 R+ A L IRVNG+AP ++T+ AL VI P + M P + +P+ Sbjct: 203 RSYALMLAADRIRVNGVAPTNCSTPMITENPALFKVIEENPHLVNAMSTALPDFPMIEPR 262 Query: 223 DIANAALFLCSPAASWVSGQILTVSGG 249 D++NA LFL S A +G +L V G Sbjct: 263 DVSNAILFLISDAGRSFTGSVLKVDAG 289 >5EJ2-A nrPDB Length = 308 Score = 87.0 bits (214), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 72/272 (26%), Positives = 119/272 (43%), Gaps = 31/272 (11%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAAN------------HVVDEI 55 R+ GK A I+GA G G+ A+ A GA ++ DI N D + Sbjct: 34 RVAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETADLV 93 Query: 56 QQLGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGG--GPKPFDMPMADFRR 113 + L + + D+ + L + D + +LG++DI+V NAG G G K + ++ Sbjct: 94 KDLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTDGRKLHKIRDNVWQD 153 Query: 114 AYELNVFSFFHLSQLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRN 172 ++N+ +H + P + G GG I+ +S+ N Y ++K L+R Sbjct: 154 MIDINLTGVWHTVKAGVPHVLSGGRGGSIVLTSSVGGRKAYPNTGHYIAAKHGVIGLMRA 213 Query: 173 MAFDLGEKNIRVNGIAPGAILT-----DALKSVITPEIE----------QKMLQHTPIRR 217 A +LG IRVN + P + T D + P++E +M+ P+ Sbjct: 214 FAVELGPHMIRVNAVLPTQVSTTMVMNDQTFRLFRPDLENPGPDDFAPISQMMHTLPVPW 273 Query: 218 LGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 + DI+NA LFL S + +V+G L V G Sbjct: 274 V-DASDISNAVLFLASDESRYVTGVSLPVDAG 304 >3A28-C nrPDB Length = 258 Score = 87.0 bits (214), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 76/253 (30%), Positives = 126/253 (49%), Gaps = 16/253 (6%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDI--NADAANHVVDEIQQLGGQAFACRCDI 69 K A++TG GIG+ I+ A G + V+D+ + A + I+ +A D+ Sbjct: 3 KVAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQEEQAAETIKLIEAADQKAVFVGLDV 62 Query: 70 TSEQELSALADFAISKLGKVDILVNNAGGGGPKP-FDMPMADFRRAYELNVFSFFHLSQL 128 T + + D A KLG D+LVNNAG KP ++ D ++ Y +NVFS F Q Sbjct: 63 TDKANFDSAIDEAAEKLGGFDVLVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQA 122 Query: 129 VAPEMEKNG--GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNG 186 + + ++ G G +I + A + I +++Y+++K A L + A +L K VN Sbjct: 123 ASRKFDELGVKGKIINAASIAAIQGFPI-LSAYSTTKFAVRGLTQAAAQELAPKGHTVNA 181 Query: 187 IAPGAILT------DALKSVITPE-IEQKMLQHTPIRRLGQ---PQDIANAALFLCSPAA 236 APG + T DA S I + I + +++ LG+ P+D+A FL S + Sbjct: 182 YAPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLASENS 241 Query: 237 SWVSGQILTVSGG 249 ++V+GQ++ V GG Sbjct: 242 NYVTGQVMLVDGG 254 >1W73-A nrPDB Length = 302 Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 74/250 (29%), Positives = 119/250 (47%), Gaps = 13/250 (5%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQ-QLGGQAFACRC 67 GK A ITG G G+GK + ++ GA V++ D ++I Q G + A +C Sbjct: 24 FQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQC 83 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYE---LNVFSFFH 124 D+ + I G +I++NNA G P + + + LN +F Sbjct: 84 DVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFVT 143 Query: 125 L---SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKN 181 L QL+ + G L+IT++ AE + + AS+KA + +++A + G+ Sbjct: 144 LEIGKQLIKAQK----GAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYG 199 Query: 182 IRVNGIAPGAILTDALKSVITPE--IEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 +R N I PG I T S + P E++M+ P RLG +++AN A FLCS ASW+ Sbjct: 200 MRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWI 259 Query: 240 SGQILTVSGG 249 +G ++ GG Sbjct: 260 NGAVIKFDGG 269 >3PPI-A nrPDB Length = 281 Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 78/258 (30%), Positives = 128/258 (49%), Gaps = 27/258 (10%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 + +G AI++G G+G+ G VV++D+ A+ + DE LG +A Sbjct: 27 QFEGASAIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADE---LGNRAEFVST 83 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGG---------PKPFDMPMADFRRAYELN 118 ++TSE + A + A ++LG++ V GG G P DM F + +L Sbjct: 84 NVTSEDSVLAAIE-AANQLGRLRYAVVAHGGFGVAQRIVQRDGSPADM--GGFTKTIDLY 140 Query: 119 VFSFFHLSQLVAP-----EMEKNG--GGVILTITSMAAENKNINMTSYASSKAAASHLVR 171 + +++++LVA E +NG G ++LT S+A I T+YA++KA L Sbjct: 141 LNGTYNVARLVAASIAAAEPRENGERGALVLT-ASIAGYEGQIGQTAYAAAKAGVIGLTI 199 Query: 172 NMAFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPI-RRLGQPQDIANAALF 230 A DL IRVN IAPG + T ++SV E K + P +RLG P + A+AA F Sbjct: 200 AAARDLSSAGIRVNTIAPGTMKTPIMESV-GEEALAKFAANIPFPKRLGTPDEFADAAAF 258 Query: 231 LCSPAASWVSGQILTVSG 248 L + +++G+++ + G Sbjct: 259 LLTN--GYINGEVMRLDG 274 >4IIV-A nrPDB Length = 267 Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 66/245 (26%), Positives = 125/245 (51%), Gaps = 13/245 (5%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASV-VVSDINADAANHVVDEIQQLGGQAFACRCDIT 70 + ++TGA GIG+ IA A G ++ V +A A ++ I GG D+ Sbjct: 27 RSVLVTGASKGIGRAIARQLAADGFNIGVHYHRDAAGAQETLNAIVANGGNGRLLSFDVA 86 Query: 71 SEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFHLSQ-L 128 + ++ + + I++ G +V+NAG F + D+ N+ SF+++ Q Sbjct: 87 NREQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPALSNDDWDAVIHTNLDSFYNVIQPC 146 Query: 129 VAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIA 188 + P + GG I+T++S++ N +Y+++KA + +A +L ++ I VN IA Sbjct: 147 IMPMIGARQGGRIITLSSVSGVMGNRGQVNYSAAKAGIIGATKALAIELAKRKITVNCIA 206 Query: 189 PGAILTDALKSVITPEIEQKMLQHT----PIRRLGQPQDIANAALFLCSPAASWVSGQIL 244 PG I T + E+E+ L+ P++R+GQ +++A A +L S A +V+ Q++ Sbjct: 207 PGLIDTGMI------EMEESALKEAMSMIPMKRMGQAEEVAGLASYLMSDIAGYVTRQVI 260 Query: 245 TVSGG 249 +++GG Sbjct: 261 SINGG 265 >3UVE-A nrPDB Length = 286 Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 72/276 (26%), Positives = 117/276 (42%), Gaps = 35/276 (12%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDE------------- 54 R++GK A +TGA G G+ A+ A GA ++ DI VVD Sbjct: 8 RVEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDLAET 67 Query: 55 ---IQQLGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAG-GGGPKPFD-MPMA 109 ++ + D+ L A D + +LG++DI+V NAG G G D Sbjct: 68 ADLVKGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNGGDTLDKTSEE 127 Query: 110 DFRRAYELNVFSFFHLSQLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASH 168 D+ ++N+ + + P M G GG I+ +S+ + Y ++K Sbjct: 128 DWTEMIDINLAGVWKTVKAGVPHMIAGGRGGSIILTSSVGGLKAYPHTGHYVAAKHGVVG 187 Query: 169 LVRNMAFDLGEKNIRVNGIAPGAILTDALKS-----VITPEIEQ----------KMLQHT 213 L+R +LG+ IRVN + P + T L + + P++E +M Sbjct: 188 LMRAFGVELGQHMIRVNSVHPTHVKTPMLHNEGTFKMFRPDLENPGPDDMAPICQMFHTL 247 Query: 214 PIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 PI + +P DI+NA LF S A +++G L + G Sbjct: 248 PIPWV-EPIDISNAVLFFASDEARYITGVTLPIDAG 282 >2B4Q-A nrPDB Length = 276 Score = 85.9 bits (211), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 71/253 (28%), Positives = 119/253 (47%), Gaps = 18/253 (7%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 L G+ A++TG GIG+ IA AGA V + +A+A + G A D Sbjct: 27 LAGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAY-GDCQAIPAD 85 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAG-GGGPKPFDMPMADFRRAYELNVFSFFHLSQ 127 ++SE LA ++DILVNNAG G P++ + + +LNV S F Q Sbjct: 86 LSSEAGARRLAQALGELSARLDILVNNAGTSWGAALESYPVSGWEKVMQLNVTSVFSCIQ 145 Query: 128 LVAPEMEKNGG----------GVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDL 177 + P + ++ G + I++M + +Y SKAA L R +A +L Sbjct: 146 QLLPLLRRSASAENPARVINIGSVAGISAMGEQ-----AYAYGPSKAALHQLSRMLAKEL 200 Query: 178 GEKNIRVNGIAPGAILTDALKSVIT-PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAA 236 ++I VN IAPG + + + P+ + P+ R G+P+++A A+ L A Sbjct: 201 VGEHINVNVIAPGRFPSRMTRHIANDPQALEADSASIPMGRWGRPEEMAALAISLAGTAG 260 Query: 237 SWVSGQILTVSGG 249 ++++G ++ + GG Sbjct: 261 AYMTGNVIPIDGG 273 >4NR0-A nrPDB Length = 273 Score = 84.3 bits (207), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 77/258 (29%), Positives = 120/258 (46%), Gaps = 25/258 (9%) Query: 9 LDGKCAIITGAGA--GIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFAC- 65 L GK A+I G + I IA GA + + N V + G + C Sbjct: 4 LTGKRALIVGVASKLSIASGIAAAMHREGAELAFTYQNDKLRGRVEEFASGWGSRPELCF 63 Query: 66 RCDITSEQELSALADFAISKLGK----VDILVNNAGGGGPKPFD------MPMADFRRAY 115 CD+ + ++ A+ + LGK +DI+V++ G D FR A+ Sbjct: 64 PCDVADDSQIEAV----FAALGKHWDGLDIIVHSVGFAPGDQLDGDFTAVTTREGFRIAH 119 Query: 116 ELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAF 175 +++ +SF L++ EM K G +LT++ + AE N +KA+ VR +A Sbjct: 120 DISAYSFIALAK-AGREMMKGRNGSLLTLSYLGAERTMPNYNVMGMAKASLEAGVRYLAG 178 Query: 176 DLGEKNIRVNGIAPGAILTDALKSVITPEIEQKML----QHTPIRRLGQPQDIANAALFL 231 LG + RVN ++ G I T A + + +KML + TP+RR +++ NA FL Sbjct: 179 SLGAEGTRVNAVSAGPIRTLAASGIKSF---RKMLAANERQTPLRRNVTIEEVGNAGAFL 235 Query: 232 CSPAASWVSGQILTVSGG 249 CS AS +SG+IL V GG Sbjct: 236 CSDLASGISGEILYVDGG 253 >2AG5-A nrPDB Length = 246 Score = 84.3 bits (207), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 71/250 (28%), Positives = 126/250 (50%), Gaps = 18/250 (7%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 RLDGK I+T A GIG+ A+ FA GA V+ +DIN + E+++ G R Sbjct: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESK----LQELEKYPG--IQTRV 56 Query: 68 -DITSEQELSALADFAISKLGKVDILVNNAGG-GGPKPFDMPMADFRRAYELNVFSFFHL 125 D+T ++++ A+ ++ ++D+L N AG D D+ + LNV S + + Sbjct: 57 LDVTKKKQIDQFAN----EVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLM 112 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKN-INMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 + P+M G I+ ++S+A+ K +N Y+++KAA L +++A D ++ IR Sbjct: 113 IKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRC 172 Query: 185 NGIAPGAILTDALKSVIT-----PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 N + PG + T +L+ I E L+ R ++IA ++L S +++V Sbjct: 173 NCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYV 232 Query: 240 SGQILTVSGG 249 +G + + GG Sbjct: 233 TGNPVIIDGG 242 >4CQM-B nrPDB Length = 244 Score = 84.0 bits (206), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 67/243 (27%), Positives = 110/243 (45%), Gaps = 13/243 (5%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 +D CA+ G+ GIG+ +A A G + V N + A + LGG A CD Sbjct: 8 MDKVCAVFGGS-RGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGD---LGGDHLAFSCD 63 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQ 127 + E ++ + LG+V+ LVN AG D N+ + Sbjct: 64 VAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCK 123 Query: 128 LVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGI 187 M + GG I+ + S+ N + Y++SK R +A ++ K IRVN + Sbjct: 124 AAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 183 Query: 188 APGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLC-SPAASWVSGQILTV 246 APG + TD K + E+ + ++ P+ R G+ ++A+A +FL SP +++G +L V Sbjct: 184 APGFVHTDMTKDL----KEEHLKKNIPLGRFGETIEVAHAVVFLLESP---YITGHVLVV 236 Query: 247 SGG 249 GG Sbjct: 237 DGG 239 >2O23-A nrPDB Length = 265 Score = 83.6 bits (205), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 72/233 (30%), Positives = 112/233 (48%), Gaps = 20/233 (8%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 + G A+ITG +G+G A GAS V+ D+ + ++LG D Sbjct: 10 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEA---QAKKLGNNCVFAPAD 66 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAG-GGGPKPFDMP------MADFRRAYELNVFS 121 +TSE+++ A K G+VD+ VN AG K +++ + DF+R ++N+ Sbjct: 67 VTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMG 126 Query: 122 FFHLSQLVAPEMEKN----GG--GVILTITSMAAENKNINMTSYASSKAAASHLVRNMAF 175 F++ +LVA EM +N GG GVI+ S+AA + +Y++SK + +A Sbjct: 127 TFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 186 Query: 176 DLGEKNIRVNGIAPGAILTDALKSVITPE-IEQKMLQHTPI-RRLGQPQDIAN 226 DL IRV IAPG T L S+ PE + + P RLG P + A+ Sbjct: 187 DLAPIGIRVMTIAPGLFGTPLLTSL--PEKVCNFLASQVPFPSRLGDPAEYAH 237 >5OVL-A nrPDB Length = 300 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 68/244 (27%), Positives = 116/244 (47%), Gaps = 23/244 (9%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITS 71 + ++TG GIG IA A G V V+ + A + + F +CD+T Sbjct: 69 RSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDL-----------FGVQCDVTD 117 Query: 72 EQELSALADFAISKL----GKVDILVNNAGGGGPKPFDMPMAD--FRRAYELNVFSFFHL 125 SA D A ++ G V++LV NAG F M M + F N+ F Sbjct: 118 ----SAAVDRAFKEVEEHQGPVEVLVANAGIS-KDAFLMRMTEERFEEVINTNLTGAFRC 172 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 +Q + M++ G I+ I S++ N +YA++KA + R+++ +L + + N Sbjct: 173 AQRASRTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTAN 232 Query: 186 GIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILT 245 +APG I T+ ++ + I+ L P +R+G +++A A FL S AS+++G ++ Sbjct: 233 VVAPGYIDTEMTRA-LDERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVIP 291 Query: 246 VSGG 249 V GG Sbjct: 292 VDGG 295 >5OVJ-A nrPDB Length = 256 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 68/244 (27%), Positives = 116/244 (47%), Gaps = 23/244 (9%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITS 71 + ++TG GIG IA A G V V+ + A + + F +CD+T Sbjct: 25 RSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDL-----------FGVQCDVTD 73 Query: 72 EQELSALADFAISKL----GKVDILVNNAGGGGPKPFDMPMAD--FRRAYELNVFSFFHL 125 SA D A ++ G V++LV NAG F M M + F N+ F Sbjct: 74 ----SAAVDRAFKEVEEHQGPVEVLVANAGIS-KDAFLMRMTEERFEEVINTNLTGAFRC 128 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 +Q + M++ G I+ I S++ N +YA++KA + R+++ +L + + N Sbjct: 129 AQRASRTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTAN 188 Query: 186 GIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILT 245 +APG I T+ ++ + I+ L P +R+G +++A A FL S AS+++G ++ Sbjct: 189 VVAPGYIDTEMTRA-LDERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVIP 247 Query: 246 VSGG 249 V GG Sbjct: 248 VDGG 251 >1E3W-A nrPDB Length = 261 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 75/257 (29%), Positives = 126/257 (49%), Gaps = 26/257 (10%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDI-NADAANHVVDEIQQLGGQAFACRC 67 + G A+ITG +G+G A GA+ V+ D+ N++ E ++LGG Sbjct: 8 VKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGET----EAKKLGGNCIFAPA 63 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAG-GGGPKPFD------MPMADFRRAYELNVF 120 ++TSE+E+ A A K G++D+ VN AG K + + DF+R +N+ Sbjct: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 Query: 121 SFFHLSQLVAPEMEKN----GG--GVILTITSMAAENKNINMTSYASSKAAASHLVRNMA 174 F++ +LVA M +N GG GVI+ S+AA + +Y++SK + +A Sbjct: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 Query: 175 FDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKML-QHTPI-RRLGQPQDIAN-AALFL 231 DL IRV IAPG T L ++ P+ + L P RLG P + A+ + + Sbjct: 184 RDLAPIGIRVVTIAPGLFATPLLTTL--PDTVRNFLASQVPFPSRLGDPAEYAHLVQMVI 241 Query: 232 CSPAASWVSGQILTVSG 248 +P +++G+++ + G Sbjct: 242 ENP---FLNGEVIRLDG 255 >4GKB-A nrPDB Length = 258 Score = 82.0 bits (201), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 56/173 (32%), Positives = 85/173 (49%), Gaps = 7/173 (4%) Query: 83 ISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLVAPEMEKNGGGVIL 142 I+ G++D LVNNAG D F + E N+ ++ ++ P + K G I+ Sbjct: 78 IATFGRLDGLVNNAGVNDGIGLDAGRDAFVASLERNLIHYYAMAHYCVPHL-KATRGAIV 136 Query: 143 TITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVIT 202 I+S A N + Y +SK A L R A L E +RVN + P ++T ++ I Sbjct: 137 NISSKTAVTGQGNTSGYCASKGAQLALTREWAVALREHGVRVNAVIPAEVMTPLYRNWIA 196 Query: 203 ----PEIE-QKMLQHTPI-RRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 PE + ++ P+ RR P +IA+ A+FL SP AS +G+ L V GG Sbjct: 197 TFEDPEAKLAEIAAKVPLGRRFTTPDEIADTAVFLLSPRASHTTGEWLFVDGG 249 >4ZJU-A nrPDB Length = 275 Score = 81.6 bits (200), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 72/249 (28%), Positives = 119/249 (47%), Gaps = 29/249 (11%) Query: 21 AGIGKEIAITFATA------GASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQE 74 AG+ +++I + A GA + + N + VDE + G CD+ + E Sbjct: 22 AGVASKLSIAYGIAQALHREGAELAFTYPN-EKLKKRVDEFAEQFGSKLVFPCDVAVDAE 80 Query: 75 LSALADFAISKLGK----VDILVNNAGGGGPKPFDMPMAD------FRRAYELNVFSFFH 124 + D A ++L K VD +V++ G D D F+ A++++ +SF Sbjct: 81 I----DNAFAELAKHWDGVDGVVHSIGFAPAHTLDGDFTDVTDRDGFKIAHDISAYSFVA 136 Query: 125 LSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 +++ P ++ G +LT+T +E N +KA+ VR +A LG IRV Sbjct: 137 MARAAKPLLQARQG-CLLTLTYQGSERVMPNYNVMGMAKASLEAGVRYLASSLGVDGIRV 195 Query: 185 NGIAPGAILTDALKSVITPEIEQKML----QHTPIRRLGQPQDIANAALFLCSPAASWVS 240 N I+ G I T A + + +KML + P++R +++ NAALFLCSP AS ++ Sbjct: 196 NAISAGPIRTLAASGIKS---FRKMLDANEKVAPLKRNVTIEEVGNAALFLCSPWASGIT 252 Query: 241 GQILTVSGG 249 G+IL V G Sbjct: 253 GEILYVDAG 261 >2X9N-A nrPDB Length = 288 Score = 79.7 bits (195), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 73/267 (27%), Positives = 117/267 (43%), Gaps = 29/267 (10%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN-ADAANHVVDEI-QQLGGQAFAC 65 ++ A++TGA IG+ IA+ G VV+ N A+AA + DE+ ++ A C Sbjct: 20 HMEAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVC 79 Query: 66 RCDITSEQELSALADFAISK----LGKVDILVNNAGGGGPKPF---DMPMADFRRAYELN 118 + D+T+ L A + I+ G+ D+LVNNA P P D + E Sbjct: 80 QADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDNSNGKTVETQ 139 Query: 119 V---------------FSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSK 163 V SF + P + ++ +M + + + Y K Sbjct: 140 VAELIGTNAIAPFLLTMSFAQRQKGTNPNCTSSNLSIVNLCDAMV-DQPCMAFSLYNMGK 198 Query: 164 AAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPI-RRLGQPQ 222 A L ++ A +L IRVNG+APG L L + E + K + P+ RR + Sbjct: 199 HALVGLTQSAALELAPYGIRVNGVAPGVSL---LPVAMGEEEKDKWRRKVPLGRREASAE 255 Query: 223 DIANAALFLCSPAASWVSGQILTVSGG 249 IA+A +FL S +A +++G I+ V GG Sbjct: 256 QIADAVIFLVSGSAQYITGSIIKVDGG 282 >5CFZ-A nrPDB Length = 305 Score = 78.6 bits (192), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 73/257 (28%), Positives = 120/257 (46%), Gaps = 26/257 (10%) Query: 9 LDGKCAIITGAGA--GIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 L GK ++TG + I IA GA + + N V + QLG + Sbjct: 47 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSD-IVLQ 105 Query: 67 CDITSEQELSALADFAISKLGKV----DILVNNAGGGGPKPFD------MPMADFRRAYE 116 CD+ + + D ++LGKV D V++ G D + F+ A++ Sbjct: 106 CDVAEDASI----DTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHD 161 Query: 117 LNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFD 176 ++ +SF +++ + N G +LT++ + AE N +KA+ VR MA Sbjct: 162 ISSYSFVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANA 219 Query: 177 LGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQH----TPIRRLGQPQDIANAALFLC 232 +G + +RVN I+ G I T A + + +KML H TPIRR +D+ N+A FLC Sbjct: 220 MGPEGVRVNAISAGPIRTLAASGI---KDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLC 276 Query: 233 SPAASWVSGQILTVSGG 249 S ++ +SG+++ V GG Sbjct: 277 SDLSAGISGEVVHVDGG 293 >4JQC-A nrPDB Length = 282 Score = 78.2 bits (191), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 73/257 (28%), Positives = 120/257 (46%), Gaps = 26/257 (10%) Query: 9 LDGKCAIITGAGA--GIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 L GK ++TG + I IA GA + + N V + QLG + Sbjct: 24 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSD-IVLQ 82 Query: 67 CDITSEQELSALADFAISKLGKV----DILVNNAGGGGPKPFD------MPMADFRRAYE 116 CD+ + + D ++LGKV D V++ G D + F+ A++ Sbjct: 83 CDVAEDASI----DTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHD 138 Query: 117 LNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFD 176 ++ +SF +++ + N G +LT++ + AE N +KA+ VR MA Sbjct: 139 ISSYSFVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANA 196 Query: 177 LGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQH----TPIRRLGQPQDIANAALFLC 232 +G + +RVN I+ G I T A + + +KML H TPIRR +D+ N+A FLC Sbjct: 197 MGPEGVRVNAISAGPIRTLAASGI---KDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLC 253 Query: 233 SPAASWVSGQILTVSGG 249 S ++ +SG+++ V GG Sbjct: 254 SDLSAGISGEVVHVDGG 270 >1BDB-A nrPDB Length = 277 Score = 78.2 bits (191), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 68/259 (26%), Positives = 116/259 (44%), Gaps = 21/259 (8%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 ++L G+ +ITG +G+G+ + F GA V V D +A + + G Sbjct: 1 MKLKGEAVLITGGASGLGRALVDRFVAEGAKVAVLD---KSAERLAELETDHGDNVLGIV 57 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAG--GGGPKPFDMPM----ADFRRAYELNVF 120 D+ S ++ A +++ GK+D L+ NAG D+P A F + +NV Sbjct: 58 GDVRSLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHINVK 117 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 + H + P + + G VI TI++ A N Y ++K A LVR +AF+L Sbjct: 118 GYIHAVKACLPALVASRGNVIFTISN-AGFYPNGGGPLYTAAKHAIVGLVRELAFELAPY 176 Query: 181 NIRVNGIAPGAILTD---------ALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFL 231 +RVNG+ G I +D K++ T + + PI R+ + ++ A +F Sbjct: 177 -VRVNGVGSGGINSDLRGPSSLGMGSKAISTVPLADMLKSVLPIGRMPEVEEYTGAYVFF 235 Query: 232 CSPA-ASWVSGQILTVSGG 249 + A+ +G +L GG Sbjct: 236 ATRGDAAPATGALLNYDGG 254 >5TF4-A nrPDB Length = 274 Score = 75.9 bits (185), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 71/250 (28%), Positives = 116/250 (46%), Gaps = 13/250 (5%) Query: 9 LDGKCAIITGAG--AGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFAC- 65 L GK +I G I IA T ++AGA + + V +++ G F C Sbjct: 10 LYGKRGLILGLANNRSIAWGIAKTASSAGAELAFTYQGEAMKKRVEPLAEEVKG--FVCG 67 Query: 66 RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-----DMPMADFRRAYELNVF 120 CD++ + A+ + K GK+D LV+ G + D+ ++F ++V+ Sbjct: 68 HCDVSDSASIDAVFNTIEKKWGKLDFLVHAIGFSDKEELSGRYVDISESNFMMTMNISVY 127 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 S L++ M + GG ILT+T AE N +KAA V+ +A DLG K Sbjct: 128 SLTALTKRAEKLM--SDGGSILTLTYYGAEKVVPNYNVMGVAKAALEASVKYLAVDLGPK 185 Query: 181 NIRVNGIAPGAILTDALKSVITPEIEQKMLQHT-PIRRLGQPQDIANAALFLCSPAASWV 239 +IRVN I+ G I T A + K ++ P+RR +++ ++AL+L S + V Sbjct: 186 HIRVNAISAGPIKTLAASGIGDFRYILKWNEYNAPLRRTVTIEEVGDSALYLLSDLSRSV 245 Query: 240 SGQILTVSGG 249 +G++ V G Sbjct: 246 TGEVHHVDSG 255 >3KZV-A nrPDB Length = 254 Score = 75.5 bits (184), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 57/188 (30%), Positives = 95/188 (50%), Gaps = 8/188 (4%) Query: 11 GKCAIITGAGAGIGKEIA-ITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDI 69 GK ++TG GIGK I + F+ +VV ++A + E + G + F DI Sbjct: 2 GKVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARSEAPLKKLKE--KYGDRFFYVVGDI 59 Query: 70 TSEQELSALADFAISKLGKVDILVNNAGGGGP--KPFDMPMADFRRAYELNVFSFFHLSQ 127 T + L L + A+ GK+D LV NAG P ++ + +++ Y++N FS L Sbjct: 60 TEDSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNEIDVNAWKKLYDINFFSIVSLVG 119 Query: 128 LVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGI 187 + PE++K G V+ ++S A + +Y SSKAA +H +A + E+ ++ + Sbjct: 120 IALPELKKTNGNVVF-VSSDACNMYFSSWGAYGSSKAALNHFAMTLANE--ERQVKAIAV 176 Query: 188 APGAILTD 195 APG + TD Sbjct: 177 APGIVDTD 184 >2GDZ-A nrPDB Length = 267 Score = 74.7 bits (182), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 64/219 (29%), Positives = 103/219 (47%), Gaps = 25/219 (11%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINAD------AANHVVDEIQQLGGQA 62 ++GK A++TGA GIG+ A GA V + D N + AA H E Q + Sbjct: 5 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQ----KT 60 Query: 63 FACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSF 122 +CD+ +Q+L + G++DILVNNAG K ++ + ++N+ S Sbjct: 61 LFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEK-------NWEKTLQINLVSV 113 Query: 123 FHLSQLVAPEMEK-NG--GGVILTITSMAAENKNINMTSYASSKAAASHLVRN--MAFDL 177 + L M K NG GG+I+ ++S+A Y +SK R+ +A +L Sbjct: 114 ISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANL 173 Query: 178 GEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIR 216 +R+N I PG + T L+S+ E E+ M Q+ + Sbjct: 174 MNSGVRLNAICPGFVNTAILESI---EKEENMGQYIEYK 209 >5YCX-A nrPDB Length = 266 Score = 73.6 bits (179), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 73/256 (28%), Positives = 118/256 (46%), Gaps = 23/256 (8%) Query: 9 LDGKCAIITGAG--AGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQ-AFAC 65 L GK ++ G I IA + AGA ++ + +V + L GQ + Sbjct: 6 LQGKTFVVMGVANQRSIAWGIARSLHNAGAKLIFTYAGERLERNVRELADTLEGQESLVL 65 Query: 66 RCDITSEQELSALADFAISKLGKVD-----ILVNNAGGGGPKPFDMPMADFRRAYELNVF 120 CD+T+++EL+A + ++G + I N + D F A ++ F Sbjct: 66 PCDVTNDEELTACFETIKQEVGTIHGVAHCIAFANRDDLKGEFVDTSRDGFLLAQNISAF 125 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAEN--KNINMTSYASSKAAASHLVRNMAFDLG 178 S +++ M + GG ILT+T + E KN N+ A + AS V+ +A DLG Sbjct: 126 SLTAVAREAKKVMTE--GGNILTLTYLGGERVVKNYNVMGVAKASLEAS--VKYLANDLG 181 Query: 179 EKNIRVNGIAPGAILTDALKSV-----ITPEIEQKMLQHTPIRRLGQPQDIANAALFLCS 233 + IRVN I+ G I T + K V I EIE++ P+RR +++ + A+FL S Sbjct: 182 QHGIRVNAISAGPIRTLSAKGVGDFNSILREIEER----APLRRTTTQEEVGDTAVFLFS 237 Query: 234 PAASWVSGQILTVSGG 249 A V+G+ + V G Sbjct: 238 DLARGVTGENIHVDSG 253 >5KOI-A nrPDB Length = 293 Score = 70.9 bits (172), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 68/250 (27%), Positives = 107/250 (42%), Gaps = 12/250 (4%) Query: 9 LDGKCAIITGAG--AGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 + GK +I G + IA A GA + + DA V + + G F Sbjct: 26 MQGKRGLIMGVANNHSLAWGIAKQLAAQGAELAFT-YQGDALGKRVKPLAEQVGSDFVLP 84 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD------FRRAYELNVF 120 CD+ + A+ + K G +D LV+ G AD F R ++ + Sbjct: 85 CDVEDIATVDAVFEEIEKKWGGLDFLVHAIGFSDKTELKGRYADVTTRENFSRTMVISAY 144 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 SF ++Q M+ GG ILT+T + N +KAA +VR +A D G + Sbjct: 145 SFTEVAQRAEKLMKD--GGSILTLTYGGSTRTIPNYNVMGVAKAALEAMVRYLAADYGPQ 202 Query: 181 NIRVNGIAPGAILTDALKSVITPE-IEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 IRVN I+ G + T A + I +++P+RR D+ +A++L S +S V Sbjct: 203 GIRVNAISAGPVRTLAGAGIGDARAIFSYQRRNSPLRRTVDIDDVGKSAVYLLSDLSSGV 262 Query: 240 SGQILTVSGG 249 +G+I V G Sbjct: 263 TGEIHFVDSG 272 >2PD3-A nrPDB Length = 275 Score = 70.5 bits (171), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 64/250 (25%), Positives = 115/250 (46%), Gaps = 13/250 (5%) Query: 9 LDGKCAIITGAG--AGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 L GK +I G I IA + GA++ + +N V Q+L + Sbjct: 4 LKGKKGLIVGVANNKSIAYGIAQSCFNQGATLAFTYLNESLEKRVRPIAQELN-SPYVYE 62 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKP------FDMPMADFRRAYELNVF 120 D++ E+ +L + LG +D +V++ PK + + F A E++V+ Sbjct: 63 LDVSKEEHFKSLYNSVKKDLGSLDFIVHSVAFA-PKEALEGSLLETSKSAFNTAMEISVY 121 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 S L+ + P + N G +LT++ + + + +KAA VR +A DLG+ Sbjct: 122 SLIELTNTLKPLL--NNGASVLTLSYLGSTKYMAHYNVMGLAKAALESAVRYLAVDLGKH 179 Query: 181 NIRVNGIAPGAILTDALKSVITPEIEQKMLQ-HTPIRRLGQPQDIANAALFLCSPAASWV 239 +IRVN ++ G I T A + + K + + P+R+ +++ NA ++L S +S V Sbjct: 180 HIRVNALSAGPIRTLASSGIADFRMILKWNEINAPLRKNVSLEEVGNAGMYLLSSLSSGV 239 Query: 240 SGQILTVSGG 249 SG++ V G Sbjct: 240 SGEVHFVDAG 249 >3GRK-A nrPDB Length = 293 Score = 70.1 bits (170), Expect = 9e-13, Method: Compositional matrix adjust. Identities = 68/243 (27%), Positives = 105/243 (43%), Gaps = 11/243 (4%) Query: 9 LDGKCAIITGAG--AGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 L GK +I G I IA AGA + + DA V+ + + G A Sbjct: 29 LQGKRGLILGVANNRSIAWGIAKAAREAGAELAFT-YQGDALKKRVEPLAEELGAFVAGH 87 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGP-----KPFDMPMADFRRAYELNVFS 121 CD+ + A+ + K GK+D LV+ G + D A+F ++V+S Sbjct: 88 CDVADAASIDAVFETLEKKWGKLDFLVHAIGFSDKDELTGRYIDTSEANFTNTMLISVYS 147 Query: 122 FFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKN 181 +S+ M GG ILT+T AE N +KAA V+ +A DLG +N Sbjct: 148 LTAVSRRAEKLMAD--GGSILTLTYYGAEKVMPNYNVMGVAKAALEASVKYLAVDLGPQN 205 Query: 182 IRVNGIAPGAILTDALKSVITPEIEQKMLQH-TPIRRLGQPQDIANAALFLCSPAASWVS 240 IRVN I+ G I T A + K ++ P+RR ++ + L+ S + V+ Sbjct: 206 IRVNAISAGPIKTLAASGIGDFRYILKWNEYNAPLRRTVTIDEVGDVGLYFLSDLSRSVT 265 Query: 241 GQI 243 G++ Sbjct: 266 GEV 268 >4DA9-A nrPDB Length = 280 Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 68/247 (27%), Positives = 109/247 (44%), Gaps = 13/247 (5%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSDI-NADAANHVVDEIQQLGGQAFACRCDITS 71 AI+TG GIG IA A +G + ++ I +A+ V+ E+ LG + R D+ Sbjct: 31 VAIVTGGRRGIGLGIARALAASGFDIAITGIGDAEGVAPVIAELSGLGARVIFLRADLAD 90 Query: 72 EQELSALADFAISKLGKVDILVNNAGGGG---PKPFDMPMADFRRAYELNVFSFFHLSQL 128 A D +++ G++D LVNNAG D+ +F +N+ +Q Sbjct: 91 LSSHQATVDAVVAEFGRIDCLVNNAGIASIVRDDFLDLKPENFDTIVGVNLRGTVFFTQA 150 Query: 129 VAPEM---EKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 V M + I+ ITS++A + Y SKA + + +A L E I V Sbjct: 151 VLKAMLASDARASRSIINITSVSAVMTSPERLDYCMSKAGLAAFSQGLALRLAETGIAVF 210 Query: 186 GIAPGAILTDALKSVITPE---IEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQ 242 + PG I +D +V IE ++ P+RR G+P+DI N L + +G Sbjct: 211 EVRPGIIRSDMTAAVSGKYDGLIESGLV---PMRRWGEPEDIGNIVAGLAGGQFGFATGS 267 Query: 243 ILTVSGG 249 ++ GG Sbjct: 268 VIQADGG 274 >1P33-A nrPDB Length = 289 Score = 68.2 bits (165), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 69/280 (24%), Positives = 115/280 (41%), Gaps = 50/280 (17%) Query: 14 AIITGAGAGIGKEIAITF-------------ATAGASVVVSDINADAANHVVDEIQQLGG 60 A++TGA +G IA + A AS + + +NA N + L Sbjct: 10 ALVTGAAKRLGSSIAEALHAEGYTVCLHYHRSAADASTLAATLNARRPNSAITVQADLSN 69 Query: 61 QAFACRCD------ITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF---------- 104 A A + +T SAL D G+ D+LVNNA P P Sbjct: 70 VATASFSETDGSVPVTLFSRCSALVDACYMHWGRCDVLVNNASSFYPTPLLRKDAGEGGS 129 Query: 105 --------DMPMADFRRAYELNVFSFFHL----SQLVA-PEMEKNGGGV-ILTITSMAAE 150 ++ AD + N + + L +Q VA E+ G I+ + Sbjct: 130 SVGDKESLEVAAADL---FGSNAIAPYFLIKAFAQRVADTRAEQRGTSYSIVNMVDAMTS 186 Query: 151 NKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPG-AILTDALKSVITPEIEQKM 209 + T Y +K A L R+ A +L IRVNG++PG ++L D + + + +K+ Sbjct: 187 QPLLGYTMYTMAKEALEGLTRSAALELASLQIRVNGVSPGLSVLPDDMPFSVQEDYRRKV 246 Query: 210 LQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 + +R +++++ +FLCSP A +++G + V GG Sbjct: 247 PLY---QRNSSAEEVSDVVIFLCSPKAKYITGTCIKVDGG 283 >5I9N-A nrPDB Length = 276 Score = 68.2 bits (165), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 62/250 (24%), Positives = 116/250 (46%), Gaps = 12/250 (4%) Query: 9 LDGKCAIITG--AGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 LDGK ++TG + I IA GA + + + + + + + G + Sbjct: 4 LDGKRILLTGLLSNRSIAYGIAKACKREGAELAFTYVGDRFKDRITEFAAEFGSE-LVFP 62 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF------DMPMADFRRAYELNVF 120 CD+ + ++ AL + +D LV++ G + + +FR A++++ + Sbjct: 63 CDVADDAQIDALFASLKTHWDSLDGLVHSIGFAPREAIAGDFLDGLTRENFRIAHDISAY 122 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 SF L++ P + + +LT++ + AE N + +KAA VR +A LG K Sbjct: 123 SFPALAKAALPMLSDDAS--LLTLSYLGAERAIPNYNTMGLAKAALEASVRYLAVSLGAK 180 Query: 181 NIRVNGIAPGAILTDALKSVIT-PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 +RVN I+ G I T A + + +I + ++P++R + + NA FL S AS V Sbjct: 181 GVRVNAISAGPIKTLAASGIKSFGKILDFVESNSPLKRNVTIEQVGNAGAFLLSDLASGV 240 Query: 240 SGQILTVSGG 249 + +++ V G Sbjct: 241 TAEVMHVDSG 250 >3RKU-A nrPDB Length = 287 Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 52/199 (26%), Positives = 91/199 (45%), Gaps = 15/199 (7%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQL--------- 58 RL K +ITGA AGIGK A+ + A D+ A ++++++L Sbjct: 30 RLAKKTVLITGASAGIGKATALEYLEASNG----DMKLILAARRLEKLEELKKTIDQEFP 85 Query: 59 GGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGG--GGPKPFDMPMADFRRAYE 116 + + DIT +++ + + +DILVNNAG G + + D + ++ Sbjct: 86 NAKVHVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQIATEDIQDVFD 145 Query: 117 LNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFD 176 NV + +++Q V P + G I+ + S+A + + Y +SK A ++ + Sbjct: 146 TNVTALINITQAVLPIFQAKNSGDIVNLGSIAGRDAYPTGSIYCASKFAVGAFTDSLRKE 205 Query: 177 LGEKNIRVNGIAPGAILTD 195 L IRV IAPG + T+ Sbjct: 206 LINTKIRVILIAPGLVETE 224 >3PXX-A nrPDB Length = 287 Score = 64.7 bits (156), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 64/281 (22%), Positives = 114/281 (40%), Gaps = 40/281 (14%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVD------------EI 55 R+ K ++TG G G+ A+ A GA +++ DI D + E+ Sbjct: 7 RVQDKVVLVTGGARGQGRSHAVKLAEEGADIILFDICHDIETNEYPLATSRDLEEAGLEV 66 Query: 56 QQLGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAY 115 ++ G +A+ D+ +S A+++ GK+D++V NA G P +P+ F A+ Sbjct: 67 EKTGRKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANA-GICPLGAHLPVQAFADAF 125 Query: 116 ELNVFSFFHLSQLVAPEMEKNGGGVILTITSMA-----------AENKNINMTSYASSKA 164 +++ + P + G I+T S+A + Y+ +K Sbjct: 126 DVDFVGVINTVHAALPYL--TSGASIITTGSVAGLIAAAQPPGAGGPQGPGGAGYSYAKQ 183 Query: 165 AASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSV-----ITPEIE-----QKMLQHTP 214 +A L ++IR N I P + TD L S P++E +L Sbjct: 184 LVDSYTLQLAAQLAPQSIRANVIHPTNVNTDMLNSAPMYRQFRPDLEAPSRADALLAFPA 243 Query: 215 IRRLGQP----QDIANAALFLCSPAASWVSGQILTVSGGGV 251 ++ + P DI+NA FL S + +V+G V G + Sbjct: 244 MQAMPTPYVEASDISNAVCFLASDESRYVTGLQFKVDAGAM 284 >3K2E-A nrPDB Length = 296 Score = 64.3 bits (155), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 59/251 (23%), Positives = 108/251 (43%), Gaps = 11/251 (4%) Query: 7 LRLDGKCAIITGAG--AGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFA 64 + ++GK +I G + IA GA V ++ + ++ VD + + G Sbjct: 26 MLMEGKKGVIIGVANDKSLAWGIAKAVCAQGAEVALTYL-SETFKKRVDPLAESLGVKLT 84 Query: 65 CRCDITSEQELSALADFAISKLGKVDILVNNAGGGGP-----KPFDMPMADFRRAYELNV 119 CD++ + + + + G +D +V+ + D + +F + ++ Sbjct: 85 VPCDVSDAESVDNMFKVLAEEWGSLDFVVHAVAFSDKNELKGRYVDTSLGNFLTSMHISC 144 Query: 120 FSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGE 179 +SF +++ P M GG ILT++ AE + KAA V+ +A DLG+ Sbjct: 145 YSFTYIASKAEPLM--TNGGSILTLSYYGAEKVVPHYNVMGVCKAALEASVKYLAVDLGK 202 Query: 180 KNIRVNGIAPGAILTDALKSVIT-PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASW 238 + IRVN I+ G + T A + I ++P+RR D+ AAL+L S Sbjct: 203 QQIRVNAISAGPVRTLASSGISDFHYILTWNKYNSPLRRNTTLDDVGGAALYLLSDLGRG 262 Query: 239 VSGQILTVSGG 249 +G+ + V G Sbjct: 263 TTGETVHVDCG 273 >3OIG-A nrPDB Length = 266 Score = 64.3 bits (155), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 64/261 (24%), Positives = 116/261 (44%), Gaps = 27/261 (10%) Query: 6 NLRLDGKCAIITGAG--AGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG--- 60 N L+G+ ++ G I IA + AGA ++ + A + + +L G Sbjct: 2 NFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTY----AGERLEKSVHELAGTLD 57 Query: 61 --QAFACRCDITSEQELSALADFAISKLGKVD-----ILVNNAGGGGPKPFDMPMADFRR 113 + CD+T++ E+ ++G + I N + + F Sbjct: 58 RNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLL 117 Query: 114 AYELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNM 173 A+ ++ +S + + P M + GG I+T+T + E N +KA+ V+ + Sbjct: 118 AHNISSYSLTAVVKAARPMMTE--GGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYL 175 Query: 174 AFDLGEKNIRVNGIAPGAILTDALKSV-----ITPEIEQKMLQHTPIRRLGQPQDIANAA 228 A DLG++NIRVN I+ G I T + K + I +IE++ P+RR P+++ + A Sbjct: 176 AADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEER----APLRRTTTPEEVGDTA 231 Query: 229 LFLCSPAASWVSGQILTVSGG 249 FL S + ++G+ L V G Sbjct: 232 AFLFSDMSRGITGENLHVDSG 252 >2O2S-A nrPDB Length = 315 Score = 62.0 bits (149), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 60/181 (33%), Positives = 87/181 (48%), Gaps = 24/181 (13%) Query: 86 LGKVDILVNNAGGGGPKPFDMPMADFRRAY----ELNVFSFFHLSQLVAPEMEKNGGGVI 141 LG +DILV++ G P+ + R+ Y + +SF L Q P M N GG Sbjct: 118 LGNIDILVHSLANG-PEVTKPLLETSRKGYLAASSNSAYSFVSLLQHFGPIM--NEGGSA 174 Query: 142 LTITSMAAENKNINMTSY----ASSKAAASHLVRNMAFDLGEK-NIRVNGIAPGAILTDA 196 +T++ +AAE + Y +S+KAA R +A++ G+K +RVN I+ G + + A Sbjct: 175 VTLSYLAAERV---VPGYGGGMSSAKAALESDTRTLAWEAGQKYGVRVNAISAGPLKSRA 231 Query: 197 L--------KSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSG 248 KS I I+ + P+RR D+ AALFL SP A VSG L V Sbjct: 232 ASAIGKSGEKSFIDYAIDYSY-NNAPLRRDLHSDDVGGAALFLLSPLARAVSGVTLYVDN 290 Query: 249 G 249 G Sbjct: 291 G 291 >4J3F-A nrPDB Length = 280 Score = 61.2 bits (147), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 66/260 (25%), Positives = 116/260 (44%), Gaps = 32/260 (12%) Query: 9 LDGKCAIITG--AGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQ---AF 63 L GK +ITG + I IA GA + + + D +++L + A Sbjct: 24 LAGKKILITGLLSNKSIAYGIAKAMHREGAELAFTYVG-----QFKDRVEKLCAEFNPAA 78 Query: 64 ACRCDITSEQELSALADFAISKLGKV----DILVNNAGGGGPKPFDMPMAD------FRR 113 CD+ S+QE+ L +LGKV D +V++ + D F Sbjct: 79 VLPCDVISDQEIKDL----FVELGKVWDGLDAIVHSIAFAPRDQLEGNFIDCVTREGFSI 134 Query: 114 AYELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNM 173 A++++ +SF L++ M KN ++ +T + AE + + +KA+ VR Sbjct: 135 AHDISAYSFAALAK-EGRSMMKNRNASMVALTYIGAEKAMPSYNTMGVAKASLEATVRYT 193 Query: 174 AFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQH----TPIRRLGQPQDIANAAL 229 A LGE I+VN ++ G I T A + +KML + +P+++ ++ N Sbjct: 194 ALALGEDGIKVNAVSAGPIKTLAASGISN---FKKMLDYNAMVSPLKKNVDIMEVGNTVA 250 Query: 230 FLCSPAASWVSGQILTVSGG 249 FLCS A+ ++G+++ V G Sbjct: 251 FLCSDMATGITGEVVHVDAG 270 >4M89-A nrPDB Length = 261 Score = 60.5 bits (145), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 53/195 (27%), Positives = 92/195 (47%), Gaps = 16/195 (8%) Query: 66 RCDITSEQELSALADFAISKLGK----VDILVNNAGGGGPKPFDMPMAD------FRRAY 115 RCD+ S+ E++ + + LGK +D LV++ G + D F A+ Sbjct: 62 RCDVASDDEINQV----FADLGKHWDGLDGLVHSIGFAPKEALSGDFLDSISREAFNTAH 117 Query: 116 ELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAF 175 E++ +S L++ P M + I+ ++ + A N +KA+ +R A Sbjct: 118 EISAYSLPALAKAARPMM-RGRNSAIVALSYLGAVRAIPNYNVMGMAKASLEAGIRFTAA 176 Query: 176 DLGEKNIRVNGIAPGAILTDALKSVIT-PEIEQKMLQHTPIRRLGQPQDIANAALFLCSP 234 LG++ IR NGI+ G I T A + ++ + H P+RR +++ N A FL S Sbjct: 177 CLGKEGIRCNGISAGPIKTLAASGIADFGKLLGHVAAHNPLRRNVTIEEVGNTAAFLLSD 236 Query: 235 AASWVSGQILTVSGG 249 +S ++G+I V GG Sbjct: 237 LSSGITGEITYVDGG 251 >2DKN-A nrPDB Length = 255 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 35/103 (33%), Positives = 54/103 (52%), Gaps = 2/103 (1%) Query: 149 AENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALK-SVITPEIEQ 207 AE + +YA SK A + L R D + +R+N +APGA+ T L+ S P + Sbjct: 143 AEQQGQTHLAYAGSKYAVTCLARRNVVDWAGRGVRLNVVAPGAVETPLLQASKADPRYGE 202 Query: 208 KMLQHT-PIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 + P+ R +P+++A A FL P AS++ G +L V GG Sbjct: 203 STRRFVAPLGRGSEPREVAEAIAFLLGPQASFIHGSVLFVDGG 245 >1ENP-A nrPDB Length = 312 Score = 58.5 bits (140), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 56/175 (32%), Positives = 87/175 (49%), Gaps = 18/175 (10%) Query: 86 LGKVDILVNNAGGGGPKPFDMPMADFRRAY----ELNVFSFFHLSQLVAPEMEKNGGGVI 141 G +DILV++ G P+ + R+ Y + +SF L P M N GG Sbjct: 127 FGSIDILVHSLANG-PEVSKPLLETSRKGYLAAISASSYSFVSLLSHFLPIM--NPGGAS 183 Query: 142 LTITSMAAENKNINMTSY----ASSKAAASHLVRNMAFDLGEK-NIRVNGIAPGAILTDA 196 +++T +A+E + Y +S+KAA R +AF+ G K NIRVN I+ G + + A Sbjct: 184 ISLTYIASERI---IPGYGGGMSSAKAALESDTRVLAFEAGRKQNIRVNTISAGPLGSRA 240 Query: 197 LKSV--ITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 K++ I IE + PI++ ++ NAA FL SP AS ++G + V G Sbjct: 241 AKAIGFIDTMIEYSY-NNAPIQKTLTADEVGNAAAFLVSPLASAITGATIYVDNG 294 >2BFA-A nrPDB Length = 288 Score = 58.2 bits (139), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 64/278 (23%), Positives = 105/278 (37%), Gaps = 46/278 (16%) Query: 14 AIITGAGAGIGKEIAITFATAGASVVV-------------SDINADAANHVVDEIQQLGG 60 A++TGA +G+ IA G +V + + +NA N + L Sbjct: 9 ALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLSN 68 Query: 61 QAFAC------RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-------DMP 107 A A +T + L + G+ D+LVNNA P P P Sbjct: 69 VATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHEP 128 Query: 108 MADFRRAYEL--------NVFSFFHLSQLVA------PEMEKNGGGVILTITSMAAENKN 153 R A E N + + L + A P + I+ + Sbjct: 129 CVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQPL 188 Query: 154 INMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPG-AILTDALKSVITPEIEQKMLQH 212 + T Y +K A L R+ A +L IRVNG+ PG ++L D + P + + Sbjct: 189 LGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLSVLVDDMP----PAVWEGHRSK 244 Query: 213 TPI-RRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 P+ +R ++++ +FLCS A +++G + V GG Sbjct: 245 VPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGG 282 >2QHX-A nrPDB Length = 328 Score = 58.2 bits (139), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 64/278 (23%), Positives = 105/278 (37%), Gaps = 46/278 (16%) Query: 14 AIITGAGAGIGKEIAITFATAGASVVV-------------SDINADAANHVVDEIQQLGG 60 A++TGA +G+ IA G +V + + +NA N + L Sbjct: 49 ALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLSN 108 Query: 61 QAFAC------RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-------DMP 107 A A +T + L + G+ D+LVNNA P P P Sbjct: 109 VATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHEP 168 Query: 108 MADFRRAYEL--------NVFSFFHLSQLVA------PEMEKNGGGVILTITSMAAENKN 153 R A E N + + L + A P + I+ + Sbjct: 169 CVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQPL 228 Query: 154 INMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPG-AILTDALKSVITPEIEQKMLQH 212 + T Y +K A L R+ A +L IRVNG+ PG ++L D + P + + Sbjct: 229 LGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLSVLVDDMP----PAVWEGHRSK 284 Query: 213 TPI-RRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 P+ +R ++++ +FLCS A +++G + V GG Sbjct: 285 VPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGG 322 >1FJH-A nrPDB Length = 257 Score = 57.4 bits (137), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 35/94 (37%), Positives = 53/94 (56%), Gaps = 2/94 (2%) Query: 158 SYASSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVIT-PEIEQKMLQHTP-I 215 +YA SK A + VR A GE +R+N IAPGA T L++ + P + + + P + Sbjct: 154 AYAGSKNALTVAVRKRAAAWGEAGVRLNTIAPGATETPLLQAGLQDPRYGESIAKFVPPM 213 Query: 216 RRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 R +P ++A+ FL SPAAS+V G + + GG Sbjct: 214 GRRAEPSEMASVIAFLMSPAASYVHGAQIVIDGG 247 >5PGZ-A nrPDB Length = 276 Score = 56.2 bits (134), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 50/162 (30%), Positives = 74/162 (45%), Gaps = 9/162 (5%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 L GK I+TGA GIG+E+A + GA VV++ + + VV +LG A Sbjct: 16 LQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGA---ASAHY 72 Query: 69 ITSEQELSALADFAISKLGK----VDILV-NNAGGGGPKPFDMPMADFRRAYELNVFSFF 123 I E A+ I K GK +D+L+ N+ F + RR E+N S+ Sbjct: 73 IAGTMEDMTFAEQFIVKAGKLMGGLDMLILNHITQTSLSLFHDDIHSVRRVMEVNFLSYV 132 Query: 124 HLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAA 165 +S P M K G I I+S+A + + Y++SK A Sbjct: 133 VMSTAALP-MLKQSNGSIAVISSLAGKMTQPMIAPYSASKFA 173 >4NK4-A nrPDB Length = 301 Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 60/250 (24%), Positives = 110/250 (44%), Gaps = 13/250 (5%) Query: 9 LDGKCAIITGAG--AGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 L GK +I G I IA +AGA + S ++ + + F Sbjct: 39 LKGKRGLIMGVANDHSIAWGIAKVLHSAGAQLAFS-YQGESIGKRLKPLALTVDSDFMIP 97 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGG------GPKPFDMPMADFRRAYELNVF 120 C++ + L + + +D +V++ GP ++ +F + ++ F Sbjct: 98 CNVEDPSSMDLLFERIKERWETLDFVVHSIAFSDKNELRGPY-YNTSRDNFIQTMLVSCF 156 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 SF + + A M GG ++T+T + N + A +K+A + +A D G Sbjct: 157 SFTEIVRRAAQLMPH--GGAMITLTYGGSMRVVPNYNAMAPAKSALESSTKYLACDYGGM 214 Query: 181 NIRVNGIAPGAILTDALKSVIT-PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 NIR+N I+ G + T A S+ +I +++P++R +DI N+AL+L S ++ V Sbjct: 215 NIRINAISAGPVRTLAGASISNGRDIAAWSKENSPLKRTVSLEDIGNSALYLLSYLSNGV 274 Query: 240 SGQILTVSGG 249 +G+I V G Sbjct: 275 TGEIHYVDCG 284 >3DWF-A nrPDB Length = 276 Score = 53.9 bits (128), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 50/162 (30%), Positives = 80/162 (49%), Gaps = 9/162 (5%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQA----FA 64 L GK I+TGA GIG+EIA A GA VVV+ + +A VV +LG + Sbjct: 9 LQGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASAHYIAG 68 Query: 65 CRCDITSEQELSALADFAISKLGKVDILV-NNAGGGGPKPFDMPMADFRRAYELNVFSFF 123 D+T +E A A + +G +D+L+ N+ F + + R++ E+N SF Sbjct: 69 SMEDMTFAEEFVAEAG---NLMGGLDMLILNHVLYNRLTFFHGEIDNVRKSMEVNFHSFV 125 Query: 124 HLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAA 165 LS P + ++ G I ++S+A + + Y++SK A Sbjct: 126 VLSVAAMPMLMQSQGS-IAVVSSVAGKITYPLIAPYSASKFA 166 >2NWQ-A nrPDB Length = 272 Score = 53.5 bits (127), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 55/226 (24%), Positives = 95/226 (42%), Gaps = 17/226 (7%) Query: 15 IITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQE 74 ITGA +G G+ A FA AG S+V++ + + E+ + D+ Sbjct: 25 FITGATSGFGEACARRFAEAGWSLVLTGRREERLQALAGELSA-KTRVLPLTLDVRDRAA 83 Query: 75 LSALADFAISKLGKVDILVNNAG---GGGPKPFDMPMADFRRAYELNVFSFFHLSQLVAP 131 +SA D + + L+NNAG G P + D+ + N+ + ++L+ P Sbjct: 84 MSAAVDNLPEEFATLRGLINNAGLALGTDPAQ-SCDLDDWDTMVDTNIKGLLYSTRLLLP 142 Query: 132 EMEKNGGGV-ILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPG 190 + +G G I+ + S+A + Y +KA N+ DL +RV + PG Sbjct: 143 RLIAHGAGASIVNLGSVAGKWPYPGSHVYGGTKAFVEQFSLNLRCDLQGTGVRVTNLEPG 202 Query: 191 AILTDALKSVITPEIEQKMLQHT-----PIRRLGQPQDIANAALFL 231 L ++ S++ +Q T PI QP+DIA ++ Sbjct: 203 --LCESEFSLVRFGGDQARYDKTYAGAHPI----QPEDIAETIFWI 242 >4ALL-A nrPDB Length = 277 Score = 53.5 bits (127), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 70/265 (26%), Positives = 112/265 (42%), Gaps = 37/265 (13%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATA------GASVVVSDINADAANHVVDEIQQLGG 60 L L+ K +I G I + +I F A GA +V + + + ++QL Sbjct: 23 LNLENKTYVIMG----IANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQ 78 Query: 61 -QAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNV 119 +A + D+ S++E+ I+ ++ V N G M D R + Sbjct: 79 PEAHLYQIDVQSDEEV-------INGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETS 131 Query: 120 FSFFHLSQ--------LVAPEMEK--NGGGVILTITSMAAENKNINMTSYASSKAAASHL 169 F L+Q +VA E +K GG I+ T + E N +KA+ Sbjct: 132 REGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEAN 191 Query: 170 VRNMAFDLGEKNIRVNGIAPGAILTDALKSV-----ITPEIEQKMLQHTPIRRLGQPQDI 224 V+ +A DLG NIRVN I+ G I T + K V I EIE++ P++R ++ Sbjct: 192 VKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEER----APLKRNVDQVEV 247 Query: 225 ANAALFLCSPAASWVSGQILTVSGG 249 A +L S +S V+G+ + V G Sbjct: 248 GKTAAYLLSDLSSGVTGENIHVDSG 272 >5L51-A nrPDB Length = 324 Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 31/94 (32%), Positives = 52/94 (55%), Gaps = 5/94 (5%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINA----DAANHVVDEI-QQLGGQAFACR 66 + A++TGA GIG EI A+ G +V+++ + +A ++ E+ + G + + Sbjct: 16 RYAVVTGANKGIGFEICKQLASKGITVILASRDEKRGIEARERLIKELGSEFGDYVVSQQ 75 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGG 100 D+ ++AL DF +K G +DILVNNAG G Sbjct: 76 LDVADPASVAALVDFIKTKFGSLDILVNNAGLNG 109 >3O26-A nrPDB Length = 311 Score = 52.0 bits (123), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 31/91 (34%), Positives = 51/91 (56%), Gaps = 2/91 (2%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFAC-RCDIT 70 +CA++TG GIG EI ++ G VV++ + + V++++ + + D+T Sbjct: 13 RCAVVTGGNKGIGFEICKQLSSNGIMVVLTCRDVTKGHEAVEKLKNSNHENVVFHQLDVT 72 Query: 71 SE-QELSALADFAISKLGKVDILVNNAGGGG 100 +S+LADF + GK+DILVNNAG G Sbjct: 73 DPIATMSSLADFIKTHFGKLDILVNNAGVAG 103 >5LCX-A nrPDB Length = 316 Score = 51.6 bits (122), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 33/93 (35%), Positives = 50/93 (53%), Gaps = 4/93 (4%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINA----DAANHVVDEIQQLGGQAFACRC 67 + A++TGA GIG EI A G V+++ N +A ++ E+ + + Sbjct: 8 RYALVTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKELNVSENRLVFHQL 67 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGG 100 D+T ++A+A F SK GK+DILVNNAG G Sbjct: 68 DVTDLASVAAVAVFIKSKFGKLDILVNNAGVSG 100 >3UCF-A nrPDB Length = 223 Score = 51.2 bits (121), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 50/190 (26%), Positives = 85/190 (44%), Gaps = 15/190 (7%) Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGP--KPFDMPMADFRRAYELNVFSFFH 124 DI+ E+ + +G D L+ AG P K D+ + + A++ + Sbjct: 42 LDISDEKSVYHY----FETIGAFDHLIVTAGSYAPAGKVVDVEVTQAKYAFDTKFWGAV- 96 Query: 125 LSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 L+ K GG + LT + M + N A+ AA + +A +L IRV Sbjct: 97 LAAKHGARYLKQGGSITLT-SGMLSRKVVANTYVKAAINAAIEATTKVLAKELAP--IRV 153 Query: 185 NGIAPGAILTDALKSVITPE---IEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSG 241 N I+PG T+A K + + + Q+ H P+ ++G+ DIA A LF S+++G Sbjct: 154 NAISPGLTKTEAYKGMNADDRDAMYQRTQSHLPVGKVGEASDIAMAYLFAIQN--SYMTG 211 Query: 242 QILTVSGGGV 251 ++ V GG + Sbjct: 212 TVIDVDGGAL 221 >5ILO-A nrPDB Length = 271 Score = 48.9 bits (115), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 52/207 (25%), Positives = 92/207 (44%), Gaps = 23/207 (11%) Query: 11 GKCAIITGAGAGIGKEIAITFATAGAS-VVVSDINADAANHVVDEIQQLGGQAFACRCDI 69 GK A++TG GIG +++ AGA+ V + D+ + V + D+ Sbjct: 15 GKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDV 74 Query: 70 TSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLV 129 +++ + A + G +DI+VN AG K D +R +N+ + + Sbjct: 75 ANKKGVEATYEEIAKTFGNIDIVVNVAGIFNDK-------DVQRTLLVNLGGIINSTLSA 127 Query: 130 APEMEK-NG--GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNG 186 P M K NG GG+++ ++S+ + + Y ++KA + R +A EK + +G Sbjct: 128 LPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLA---NEKYYQRSG 184 Query: 187 I-----APGAILTDAL----KSVITPE 204 I PGA +TD + +I PE Sbjct: 185 IKFVTVCPGATMTDMFTNFTEKIIFPE 211 >2PTG-A nrPDB Length = 319 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 57/207 (27%), Positives = 99/207 (47%), Gaps = 32/207 (15%) Query: 68 DITSEQELSALADFAISKL--------GKVDILVNNAGGGGPKPFDMPMADFRRAY---- 115 +++S + + + F IS++ G++DILV++ G P+ + R+ Y Sbjct: 105 EVSSNKRYAGVGGFTISEVAEAVRADVGQIDILVHSLANG-PEVTKPLLQTSRKGYLAAV 163 Query: 116 ELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSY----ASSKAAASHLVR 171 + +SF L Q P M++ GG L ++ +A+E + Y +S+KAA R Sbjct: 164 SSSSYSFVSLLQHFLPLMKE--GGSALALSYIASEKV---IPGYGGGMSSAKAALESDCR 218 Query: 172 NMAFDLGE-KNIRVNGIAPGAILTDAL--------KSVITPEIEQKMLQHTPIRRLGQPQ 222 +AF+ G + +RVN I+ G + + A K+ I I+ + P+++ + Sbjct: 219 TLAFEAGRARAVRVNCISAGPLKSRAASAIGKAGDKTFIDLAIDYSE-ANAPLQKELESD 277 Query: 223 DIANAALFLCSPAASWVSGQILTVSGG 249 D+ AALFL SP A V+G L V G Sbjct: 278 DVGRAALFLLSPLARAVTGATLYVDNG 304 >2HRB-A nrPDB Length = 274 Score = 45.1 bits (105), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 55/232 (23%), Positives = 85/232 (36%), Gaps = 51/232 (21%) Query: 12 KCAIITGAGAGIGKEIAITFATA-GASVVVSDINADAANHVVDEIQQLGGQAFACRCDIT 70 + A++TGA GIG IA VV++ + V ++Q G + DI Sbjct: 3 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDID 62 Query: 71 SEQELSALADFAISKLGKVDILVNNAG----GGGPKPFDMPMADFRRAYELNVFSFFHLS 126 Q + AL DF + G +++LVNNA P PFD+ + N F+ ++ Sbjct: 63 DLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAE---MTLKTNFFATRNMC 119 Query: 127 QLVAPEMEKNG--------------------------------GGVILTITSMAAENKN- 153 + P M+ +G G ++ + + KN Sbjct: 120 NELLPIMKPHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNE 179 Query: 154 ------INMTSYASSKAAASHLVRNMAFDLGEK----NIRVNGIAPGAILTD 195 + Y SK + L R +A L EK I VN PG + TD Sbjct: 180 VHEREGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTD 231 >3ORF-A nrPDB Length = 251 Score = 44.7 bits (104), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 42/173 (24%), Positives = 79/173 (45%), Gaps = 24/173 (13%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDI----NADAANHVVDEIQQLGGQAFACRC 67 K ++ G +G E+ F + + + D NAD + + D Sbjct: 23 KNILVLGGSGALGAEVVKFFKSKSWNTISIDFRENPNADHSFTIKD-------------- 68 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGG--GGPKPFDMPMADFRRAYELNVFSFFHL 125 + E+E+ ++ + SK KVD V AGG GG D + + ++N++S F Sbjct: 69 --SGEEEIKSVIEKINSKSIKVDTFVCAAGGWSGGNASSDEFLKSVKGMIDMNLYSAFAS 126 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLG 178 + + A + N GG+ + + AA N+ M +Y ++KAA H+++++A + G Sbjct: 127 AHIGAKLL--NQGGLFVLTGASAALNRTSGMIAYGATKAATHHIIKDLASENG 177 >3U9L-A nrPDB Length = 324 Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 51/193 (26%), Positives = 84/193 (43%), Gaps = 13/193 (6%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAF-------A 64 K +ITGA +G G+ A A AG V S D ++ + G A Sbjct: 6 KIILITGASSGFGRLTAEALAGAGHRVYAS--MRDIVGRNASNVEAIAGFARDNDVDLRT 63 Query: 65 CRCDITSEQELSALADFAISKLGKVDILVNNAGGG--GPKPFDMPMADFRRAYELNVFSF 122 D+ S+ + D I + G++D+L++NAG GP P F Y++NV S Sbjct: 64 LELDVQSQVSVDRAIDQIIGEDGRIDVLIHNAGHMVFGPAEAFTP-EQFAELYDINVLST 122 Query: 123 FHLSQLVAPEMEKNGGGVILTI-TSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKN 181 +++ P M + G+++ I +S +A + Y ++KAA + A +L Sbjct: 123 QRVNRAALPHMRRQKHGLLIWISSSSSAGGTPPYLAPYFAAKAAMDAIAVQYARELSRWG 182 Query: 182 IRVNGIAPGAILT 194 I + I PGA + Sbjct: 183 IETSIIVPGAFTS 195 >4DRY-A nrPDB Length = 281 Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 48/173 (27%), Positives = 83/173 (47%), Gaps = 7/173 (4%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEI-QQLGGQAFACRCD 68 +G+ A++TG G G+G+ IA + G SVV++ D + EI + G A CD Sbjct: 32 EGRIALVTGGGTGVGRGIAQALSAEGYSVVITGRRPDVLDAAAGEIGGRTGNIVRAVVCD 91 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYEL---NVFSFFHL 125 + +++AL ++ ++D+LVNNAG P P + F + + N+ F Sbjct: 92 VGDPDQVAALFAAVRAEFARLDLLVNNAGSNVP-PVPLEEVTFEQWNGIVAANLTGAFLC 150 Query: 126 SQLVAPEMEKNG--GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFD 176 +Q M+ GG I+ S++A+ N Y ++K A + L ++ A D Sbjct: 151 TQHAFRMMKAQTPRGGRIINNGSISAQTPRPNSAPYTATKHAITGLTKSTALD 203 >1N5D-A nrPDB Length = 288 Score = 40.4 bits (93), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 11/103 (10%) Query: 12 KCAIITGAGAGIG----KEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 + A++TGA GIG +++ FA VV++ + V ++Q G + Sbjct: 5 RVALVTGANKGIGFAIVRDLCRQFA---GDVVLTARDVARGQAAVKQLQAEGLSPRFHQL 61 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGG----GPKPFDM 106 DI Q + AL DF + G +D+LVNNA P PF + Sbjct: 62 DIIDLQSIRALCDFLRKEYGGLDVLVNNAAIAFQLDNPTPFHI 104 >4Z3K-A nrPDB Length = 275 Score = 40.0 bits (92), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 54/213 (25%), Positives = 99/213 (46%), Gaps = 23/213 (10%) Query: 15 IITGAGAGIGK---EIAITFATAGASVVVSDINADAANHVVDEI--QQLGGQAFACRCDI 69 ++TGA G G+ + + + G+ +V+S N +A + E+ ++ G + D+ Sbjct: 25 LLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADL 84 Query: 70 TSE----QELSALADFAISKLGKVDILVNNAGGGG--PKPFDMPMADFRRA---YELNVF 120 +E Q L AL + K + +L+NNAG G K F + ++D + + LN+ Sbjct: 85 GAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGF-VDLSDSTQVNNYWALNLT 143 Query: 121 SFFHLSQLVAPEMEKNGG--GVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLG 178 S L+ V + G ++ I+S+ A Y + KAA L + +A + Sbjct: 144 SMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE-- 201 Query: 179 EKNIRVNGIAPGAILTD----ALKSVITPEIEQ 207 E N+RV APG + TD A ++ + P++ + Sbjct: 202 EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRK 234 >3BHI-A nrPDB Length = 276 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 5/98 (5%) Query: 14 AIITGAGAGIGKEIAITFATA-GASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSE 72 A++TG GIG I VV++ + V ++Q G + DI Sbjct: 7 ALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDDL 66 Query: 73 QELSALADFAISKLGKVDILVNNAG----GGGPKPFDM 106 Q + AL DF + G +D+LVNNAG P PF + Sbjct: 67 QSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHI 104 >4HWK-A nrPDB Length = 288 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 54/213 (25%), Positives = 99/213 (46%), Gaps = 23/213 (10%) Query: 15 IITGAGAGIGK---EIAITFATAGASVVVSDINADAANHVVDEI--QQLGGQAFACRCDI 69 ++TGA G G+ + + + G+ +V+S N +A + E+ ++ G + D+ Sbjct: 38 LLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADL 97 Query: 70 TSE----QELSALADFAISKLGKVDILVNNAGGGG--PKPFDMPMADFRRA---YELNVF 120 +E Q L AL + K + +L+NNAG G K F + ++D + + LN+ Sbjct: 98 GAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGF-VDLSDSTQVNNYWALNLT 156 Query: 121 SFFHLSQLVAPEMEKNGG--GVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLG 178 S L+ V + G ++ I+S+ A Y + KAA L + +A + Sbjct: 157 SMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE-- 214 Query: 179 EKNIRVNGIAPGAILTD----ALKSVITPEIEQ 207 E N+RV APG + TD A ++ + P++ + Sbjct: 215 EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRK 247 >3E9N-A nrPDB Length = 245 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 63/246 (25%), Positives = 105/246 (42%), Gaps = 54/246 (21%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 + L K A++TGA G+G EI V D++ D H+V + + + A Sbjct: 1 MSLKKKIAVVTGATGGMGIEI------------VKDLSRD---HIVYALGR-NPEHLAAL 44 Query: 67 CDITSEQELSA------LADFAISKL---GKVDILVNNAGGGGPKPFDM-PMADFRRAYE 116 +I + + + L + + KL VD LV+ A + +A++ + Sbjct: 45 AEIEGVEPIESDIVKEVLEEGGVDKLKNLDHVDTLVHAAAVARDTTIEAGSVAEWHAHLD 104 Query: 117 LNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMA-- 174 LNV LS+ + P + + G ++ I S A + T YA+SK H +R +A Sbjct: 105 LNVIVPAELSRQLLPAL-RAASGCVIYINSGAGNGPHPGNTIYAASK----HALRGLADA 159 Query: 175 FDLGEKN--IRVNGIAPGAILTDALKSVI-------TPEIEQKMLQHTPIRRLGQPQDIA 225 F E N IRV+ ++PG T L+ ++ PEI +P++IA Sbjct: 160 FRKEEANNGIRVSTVSPGPTNTPMLQGLMDSQGTNFRPEI------------YIEPKEIA 207 Query: 226 NAALFL 231 NA F+ Sbjct: 208 NAIRFV 213 >1A27-A nrPDB Length = 289 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 49/208 (23%), Positives = 86/208 (41%), Gaps = 30/208 (14%) Query: 15 IITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQ--------AFAC- 65 +ITG +GIG +A+ A+ + + V ++ L Q A AC Sbjct: 6 LITGCSSGIGLHLAVRLAS----------DPSQSFKVYATLRDLKTQGRLWEAARALACP 55 Query: 66 -------RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD-FRRAYEL 117 + D+ + ++A + G+VD+LV NAG G P + D ++ Sbjct: 56 PGSLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDV 113 Query: 118 NVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDL 177 NV + Q P+M++ G G +L S+ Y +SK A L ++A L Sbjct: 114 NVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLL 173 Query: 178 GEKNIRVNGIAPGAILTDALKSVI-TPE 204 + ++ I G + T ++ V+ +PE Sbjct: 174 LPFGVHLSLIECGPVHTAFMEKVLGSPE 201 >6CGE-A nrPDB Length = 328 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 49/208 (23%), Positives = 86/208 (41%), Gaps = 30/208 (14%) Query: 15 IITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQ--------AFAC- 65 +ITG +GIG +A+ A+ + + V ++ L Q A AC Sbjct: 7 LITGCSSGIGLHLAVRLAS----------DPSQSFKVYATLRDLKTQGRLWEAARALACP 56 Query: 66 -------RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD-FRRAYEL 117 + D+ + ++A + G+VD+LV NAG G P + D ++ Sbjct: 57 PGSLETLQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDV 114 Query: 118 NVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDL 177 NV + Q P+M++ G G +L S+ Y +SK A L ++A L Sbjct: 115 NVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLL 174 Query: 178 GEKNIRVNGIAPGAILTDALKSVI-TPE 204 + ++ I G + T ++ V+ +PE Sbjct: 175 LPFGVHLSLIECGPVHTAFMEKVLGSPE 202 >5WQO-A nrPDB Length = 234 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 44/187 (23%), Positives = 81/187 (43%), Gaps = 10/187 (5%) Query: 15 IITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQE 74 +I GA GIG +A F GA V + + ++ G + A D+ Sbjct: 10 LIVGASRGIGLGLADAFLQRGAQVFAVARRPQGSPGLQALAERAGERLQAVTGDLNQHDC 69 Query: 75 LSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYEL---NVFSFFHLSQLVAP 131 + + + ++D L+ NAG GP+ D+ D + +L N + L++ ++ Sbjct: 70 AERIGEMLGER--RIDRLIVNAGIYGPQQQDVAEIDAEQTAQLFLTNAIAPLRLARALSG 127 Query: 132 EMEKNGGGVILTITSMAAE---NKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIA 188 + + GGV+ ++S A + M Y +SKAA + LVR+ + E + + Sbjct: 128 RVSR--GGVVAFMSSQMASLALGLSATMPLYGASKAALNSLVRSWEGEFEELPFSLLLLH 185 Query: 189 PGAILTD 195 PG + T+ Sbjct: 186 PGWVRTE 192 >1OAA-A nrPDB Length = 259 Score = 34.7 bits (78), Expect = 0.037, Method: Compositional matrix adjust. Identities = 53/218 (24%), Positives = 97/218 (44%), Gaps = 23/218 (10%) Query: 13 CAI--ITGAGAGIGKEIAITFA---TAGASVVVSDINADAANHVVDEI--QQLGGQAFAC 65 CA+ +TGA G G+ +A A + G+ ++VS + + +E+ QQ + Sbjct: 6 CAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLA 65 Query: 66 RCDITSE----QELSALADFAISKLGKVDILVNNAG--GGGPKPF--DMPMADFRRAYEL 117 D+ +E + LSA+ + + + +L+NNA G K F +A+ + L Sbjct: 66 AADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYWAL 125 Query: 118 NVFSFFHLSQLVAPEMEKNGG--GVILTITSMAAENKNINMTSYASSKAAASHLVRNMAF 175 N+ S L+ + + G ++ I+S+ A Y + KAA L + +A Sbjct: 126 NLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAA 185 Query: 176 DLGEKNIRVNGIAPGAILTD----ALKSVITPEIEQKM 209 + E ++RV APG + D A ++ PE+ K+ Sbjct: 186 E--EPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKL 221 >4HBG-A nrPDB Length = 286 Score = 34.7 bits (78), Expect = 0.043, Method: Compositional matrix adjust. Identities = 57/247 (23%), Positives = 99/247 (40%), Gaps = 49/247 (19%) Query: 14 AIITGAGAGIGKEIAITFATAGASVVVSDINADAANHV-VDEIQQLGGQAFACRCDITSE 72 AI+TGA GIGK I G S ++ ++ +D Q G ++ +C I + Sbjct: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 Query: 73 --------------------------QELSALADFAIS-----KLGKVDILVNNAG---- 97 Q+ S L D + V++L+N AG Sbjct: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 Query: 98 -----GGGPKPFDMPMADFRRAYELN--VFSFFHLSQLVAPEME-KNGGGVILTITSMAA 149 + D+ +F + + SQ PE+ ++ I+ I+S+ Sbjct: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 Query: 150 ENK-NINMTS-YASSKAAASHLVRNMAFDLGEKNIRVNGIAPGAIL-TDALKSVITPEIE 206 K + TS Y++SKAA S +A ++ +NIR I+PG + TD ++++ P Sbjct: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL--PVEA 244 Query: 207 QKMLQHT 213 ++ML+ T Sbjct: 245 KEMLERT 251 >3F3S-A nrPDB Length = 313 Score = 32.3 bits (72), Expect = 0.22, Method: Compositional matrix adjust. Identities = 20/70 (28%), Positives = 39/70 (55%), Gaps = 4/70 (5%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQ---QLGGQAFACRCDI 69 C +I G+G IG+ A+ FA+ G V + DI + ++ I+ +L QA + + + Sbjct: 5 CVVIVGSGV-IGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSL 63 Query: 70 TSEQELSALA 79 + E++LS ++ Sbjct: 64 SVEEQLSLIS 73 >2O2Y-A nrPDB Length = 349 Score = 31.2 bits (69), Expect = 0.44, Method: Compositional matrix adjust. Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 8/83 (9%) Query: 167 SHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIAN 226 SH V N+ + GEK + N + D E +K + P+R+ DI + Sbjct: 259 SHDVHNIMNNSGEKEEKKNSASQNYTFID-----YAIEYSEK---YAPLRQKLLSTDIGS 310 Query: 227 AALFLCSPAASWVSGQILTVSGG 249 A FL S + ++GQ + V G Sbjct: 311 VASFLLSRESRAITGQTIYVDNG 333 >6ACF-A nrPDB Length = 367 Score = 30.8 bits (68), Expect = 0.57, Method: Compositional matrix adjust. Identities = 40/162 (24%), Positives = 66/162 (40%), Gaps = 27/162 (16%) Query: 2 FNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQ 61 F SD+L +GK + G G + + GA ++V+DIN +A V+E G + Sbjct: 166 FGSDSL--EGKVVAVQGVG-NVAYHLCRHLHEEGAKLIVTDINKEAVARAVEE---FGAK 219 Query: 62 A------FACRCDITSEQELSALA-DFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRA 114 A + CDI + L + D I +L K ++ +A +P M Sbjct: 220 AVDPNDIYGVECDIFAPCALGGIINDQTIPQL-KAKVIAGSANNQLKEPRHGDM-----I 273 Query: 115 YELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINM 156 +E+ + + AP+ N GGVI + N+ M Sbjct: 274 HEMGI--------VYAPDYVINAGGVINVADELYGYNRERAM 307 >2G2K-A nrPDB Length = 170 Score = 30.4 bits (67), Expect = 0.75, Method: Compositional matrix adjust. Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 6/95 (6%) Query: 117 LNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFD 176 ++ F + + +L+A ++E G G+ I +M K +N +K L FD Sbjct: 10 MDQFYRYKMPRLIA-KVEGKGNGIKTVIVNMVDVAKALNRPPTYPTKYFGCELGAQTQFD 68 Query: 177 LGEKNIRVNGIAPGAILTDAL-----KSVITPEIE 206 + VNG L D L K V+ PE E Sbjct: 69 VKNDRYIVNGSHEANKLQDMLDGFIKKFVLCPECE 103 >2E9H-A nrPDB Length = 157 Score = 30.4 bits (67), Expect = 0.87, Method: Compositional matrix adjust. Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 6/92 (6%) Query: 120 FSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGE 179 F + + +L+A ++E G G+ I +M K +N +K L FD+ Sbjct: 20 FYRYKMPRLIA-KVEGKGNGIKTVIVNMVDVAKALNRPPTYPTKYFGCELGAQTQFDVKN 78 Query: 180 KNIRVNGIAPGAILTDAL-----KSVITPEIE 206 VNG L D L K V+ PE E Sbjct: 79 DRYIVNGSHEANKLQDMLDGFIKKFVLCPECE 110 >3EWG-A nrPDB Length = 91 Score = 29.6 bits (65), Expect = 1.4, Method: Compositional matrix adjust. Identities = 16/60 (26%), Positives = 30/60 (50%), Gaps = 8/60 (13%) Query: 147 MAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVITPEIE 206 +A+E+ + A +K L++ M RV GI PG I + ++ ++TP++E Sbjct: 34 LASESLKGYVLVEAETKGDVEELIKGMP--------RVRGIVPGTIAIEEIEPLLTPKLE 85 >3ENK-A nrPDB Length = 341 Score = 29.6 bits (65), Expect = 1.5, Method: Compositional matrix adjust. Identities = 16/67 (23%), Positives = 33/67 (49%), Gaps = 1/67 (1%) Query: 15 IITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR-CDITSEQ 73 ++TG IG A+ G VV++D ++ + I+++ G+ A D++ E+ Sbjct: 9 LVTGGAGYIGSHTAVELLAHGYDVVIADNLVNSKREAIARIEKITGKTPAFHETDVSDER 68 Query: 74 ELSALAD 80 L+ + D Sbjct: 69 ALARIFD 75 >6GAZ-AN nrPDB Length = 128 Score = 29.3 bits (64), Expect = 1.7, Method: Compositional matrix adjust. Identities = 19/80 (23%), Positives = 34/80 (42%), Gaps = 1/80 (1%) Query: 138 GGVILTITSMAAENKNINMTSY-ASSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDA 196 G ++ T+ M + + + SY K R MA++ ++ +R+N + IL Sbjct: 7 GFLLRTVRQMVPSSASGQVRSYYVDWKMLRDVKRRKMAYEYADERLRINSLRKNTILPKD 66 Query: 197 LKSVITPEIEQKMLQHTPIR 216 L+ V EI P+R Sbjct: 67 LQEVADEEIASLPRDSCPVR 86 >3X2F-A nrPDB Length = 411 Score = 29.3 bits (64), Expect = 1.7, Method: Compositional matrix adjust. Identities = 25/92 (27%), Positives = 44/92 (47%), Gaps = 12/92 (13%) Query: 1 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG 60 + + NL + GK ++ G G G+ IA+ A GA V+V++ VD ++ + Sbjct: 187 IMRNTNLLVAGKNVVVAGYG-WCGRGIALRAAGLGARVIVTE---------VDPVKAV-- 234 Query: 61 QAFACRCDITSEQELSALADFAISKLGKVDIL 92 +A + +E +ADF I+ G D+L Sbjct: 235 EAIMDGFTVMPMKEAVKIADFVITASGNTDVL 266 >1MG5-A nrPDB Length = 255 Score = 29.3 bits (64), Expect = 1.8, Method: Compositional matrix adjust. Identities = 30/147 (20%), Positives = 57/147 (38%), Gaps = 15/147 (10%) Query: 74 ELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLVAPEM 133 E + L ++L VD+L+N AG + R +N + + + Sbjct: 71 ETTKLLKTIFAQLKTVDVLINGAG-------ILDDHQIERTIAVNYTGLVNTTTAILDFW 123 Query: 134 EKNGGG---VILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPG 190 +K GG +I I S+ N + Y+ +KAA + ++A + + PG Sbjct: 124 DKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAKLAPITGVTAYTVNPG 183 Query: 191 AILTDALKSV-----ITPEIEQKMLQH 212 T + + P++ +K+L H Sbjct: 184 ITRTTLVHKFNSWLDVEPQVAEKLLAH 210 >3OND-A nrPDB Length = 488 Score = 29.3 bits (64), Expect = 1.9, Method: Compositional matrix adjust. Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 12/93 (12%) Query: 1 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG 60 + + ++ + GK A++ G G +GK A AGA V+V++I+ A E G Sbjct: 255 LMRATDVMIAGKVAVVAGYG-DVGKGCAAALKQAGARVIVTEIDPICALQATME----GL 309 Query: 61 QAFACRCDITSEQELSALADFAISKLGKVDILV 93 Q D+ SE AD ++ G DI++ Sbjct: 310 QVLTLE-DVVSE------ADIFVTTTGNKDIIM 335 >4LIS-A nrPDB Length = 371 Score = 28.9 bits (63), Expect = 2.5, Method: Compositional matrix adjust. Identities = 28/112 (25%), Positives = 48/112 (42%), Gaps = 18/112 (16%) Query: 15 IITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG-QAFACRCDITSEQ 73 ++TG IG + AG VVV+D +++ ++ I+ + G +A + D+T E Sbjct: 7 LVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELISGKKAEFAQLDVTDE- 65 Query: 74 ELSALADFAISKLGKVDILVNNA-----GGGGPKPFDMPMADFRRAYELNVF 120 A D +D +++ A G G KP D Y +NV+ Sbjct: 66 ---AAFDKVFEAHPDIDSVIHFAALKAVGESGEKPLDY--------YHVNVY 106 >6DEB-A nrPDB Length = 285 Score = 28.5 bits (62), Expect = 3.0, Method: Compositional matrix adjust. Identities = 15/43 (34%), Positives = 24/43 (55%) Query: 1 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDI 43 + + + L+GK A+I GA +G+ +A AGA+V V I Sbjct: 150 LLKAYEIDLEGKDAVIIGASNIVGRPMATMLLNAGATVSVCHI 192 >3J9M-AK nrPDB Length = 128 Score = 28.1 bits (61), Expect = 3.4, Method: Compositional matrix adjust. Identities = 18/80 (22%), Positives = 33/80 (41%), Gaps = 1/80 (1%) Query: 138 GGVILTITSMAAENKNINMTS-YASSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDA 196 G ++ T M + + + S Y + R MA++ ++ +R+N + IL Sbjct: 7 GSLLRTFKQMVPSSASGQVRSHYVDWRMWRDVKRRKMAYEYADERLRINSLRKNTILPKI 66 Query: 197 LKSVITPEIEQKMLQHTPIR 216 L+ V EI P+R Sbjct: 67 LQDVADEEIAALPRDSCPVR 86 >3JD5-N nrPDB Length = 128 Score = 28.1 bits (61), Expect = 3.5, Method: Compositional matrix adjust. Identities = 13/46 (28%), Positives = 22/46 (47%) Query: 171 RNMAFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIR 216 R MA++ ++ +R+N + IL L+ V EI P+R Sbjct: 41 RKMAYEYADERLRINSLRKNTILPKHLQEVADEEIAALPRDSCPVR 86 >5XU1-M nrPDB Length = 419 Score = 28.1 bits (61), Expect = 3.5, Method: Compositional matrix adjust. Identities = 31/117 (26%), Positives = 52/117 (44%), Gaps = 7/117 (5%) Query: 104 FDMPMADFRRAYELNVFSFFHLSQLVAPEMEKN-----GGGVILTITSMAAENKNINMTS 158 F+ P + E+N FS+ + +PE +++ GG I T S+AA N NI+ + Sbjct: 177 FESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLPITTNISLAA-NFNIDEIA 235 Query: 159 YASSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPI 215 + + L + +L K + G+ G A +SV+ EI+Q T I Sbjct: 236 SIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQV-ADESVVFAEIQQSFSFMTTI 291 >6GUA-A nrPDB Length = 822 Score = 27.7 bits (60), Expect = 5.6, Method: Composition-based stats. Identities = 16/52 (30%), Positives = 28/52 (53%), Gaps = 3/52 (5%) Query: 4 SDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEI 55 ++ L DG I + A G+ + + FA+AGA + + AA H+V+E+ Sbjct: 620 AEKLATDGIATIDWASTAKDGEAVDLVFASAGAEPTIETL---AALHLVNEV 668 >2QCV-A nrPDB Length = 332 Score = 27.3 bits (59), Expect = 5.9, Method: Compositional matrix adjust. Identities = 15/38 (39%), Positives = 24/38 (63%) Query: 21 AGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQL 58 +G G E A+ + +A AS+VVS ++ A V+EI+ L Sbjct: 285 SGKGIETALKYGSASASIVVSKHSSSDAMPSVEEIEAL 322 >3QKW-A nrPDB Length = 332 Score = 27.3 bits (59), Expect = 6.5, Method: Compositional matrix adjust. Identities = 31/130 (23%), Positives = 49/130 (37%), Gaps = 16/130 (12%) Query: 34 AGASVVVSDINADA--------ANHVVDEIQQLGGQAFACRC---DITSEQELSALADFA 82 A V +++IN + N V D LG + C SE ELS D Sbjct: 1 ACMRVYITNINGQSIQSTAQLCQNTVTDVAVSLGYRELGIYCYQIHTDSESELSKRLDGI 60 Query: 83 ISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLVAPEMEKNGGGVIL 142 ++ L D+++ FD + + + Y++ + F H V P M G L Sbjct: 61 VAGLRHGDVVIFQTPTWNTTEFDEKLMNKLKLYDIKIVLFIH---DVVPLM--FSGNFYL 115 Query: 143 TITSMAAENK 152 ++A NK Sbjct: 116 MDRTIAYYNK 125 >1BW9-B nrPDB Length = 356 Score = 26.9 bits (58), Expect = 8.7, Method: Compositional matrix adjust. Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 11/67 (16%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR-- 66 LDG ++ G GA +G +A A AGA ++V+D + + H V LG A A Sbjct: 174 LDGLTVLVQGLGA-VGGSLASLAAEAGAQLLVADTDTERVAHAV----ALGHTAVALEDV 228 Query: 67 ----CDI 69 CD+ Sbjct: 229 LSTPCDV 235 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1AHH-A nrPDB 324 2e-89 2PNF-A nrPDB 292 1e-79 4JRO-A nrPDB 286 5e-78 2UVD-A nrPDB 279 6e-76 3OSU-A nrPDB 279 1e-75 2HQ1-A nrPDB 275 9e-75 2C07-A nrPDB 274 2e-74 3RSH-A nrPDB 270 6e-73 3LYL-A nrPDB 264 2e-71 3WOH-A nrPDB 263 5e-71 3FTP-A nrPDB 263 5e-71 1Q7C-A nrPDB 262 9e-71 3EMK-A nrPDB 262 1e-70 4BO1-A nrPDB 261 2e-70 5CDY-A nrPDB 260 3e-70 3O4R-A nrPDB 260 5e-70 4M8S-A nrPDB 257 3e-69 1GEE-A nrPDB 257 4e-69 4K6F-A nrPDB 257 5e-69 4IIN-A nrPDB 257 5e-69 5ITV-A nrPDB 255 1e-68 2ZAT-A nrPDB 255 2e-68 4RZH-A nrPDB 253 7e-68 3EZL-A nrPDB 252 1e-67 3F9I-A nrPDB 251 2e-67 3AUT-A nrPDB 250 4e-67 3GRP-A nrPDB 250 4e-67 2EW8-A nrPDB 250 4e-67 1AE1-A nrPDB 250 6e-67 2CDH-G nrPDB 249 1e-66 4DMM-A nrPDB 248 2e-66 4NBT-A nrPDB 247 2e-66 6NRP-A nrPDB 245 1e-65 4NBV-A nrPDB 245 1e-65 2NM0-A nrPDB 244 2e-65 5U9P-A nrPDB 244 2e-65 2PH3-A nrPDB 244 3e-65 2AE2-A nrPDB 244 3e-65 3VZS-A nrPDB 242 1e-64 6CI9-A nrPDB 242 1e-64 3OEC-A nrPDB 242 1e-64 3OIC-A nrPDB 239 9e-64 5OJG-A nrPDB 238 1e-63 5VT6-A nrPDB 238 2e-63 1GEG-A nrPDB 238 2e-63 1YXM-A nrPDB 238 2e-63 4Z9Y-A nrPDB 237 3e-63 4CQL-A nrPDB 237 3e-63 3R3S-A nrPDB 237 3e-63 2Q2Q-A nrPDB 237 4e-63 5T5Q-A nrPDB 237 5e-63 5YSS-A nrPDB 234 2e-62 5OVL-A nrPDB 233 6e-62 4IIV-A nrPDB 232 9e-62 3V2G-A nrPDB 230 3e-61 4KMS-A nrPDB 230 3e-61 4RZI-B nrPDB 230 6e-61 4IS3-A nrPDB 230 7e-61 3V2H-A nrPDB 229 1e-60 4MOW-A nrPDB 229 1e-60 1NFF-A nrPDB 229 1e-60 4DBZ-A nrPDB 228 1e-60 3WTC-A nrPDB 228 2e-60 5OVJ-A nrPDB 228 2e-60 3WYE-A nrPDB 227 4e-60 2P91-A nrPDB 226 5e-60 3W8F-A nrPDB 226 6e-60 3UVE-A nrPDB 226 7e-60 1O5I-A nrPDB 225 1e-59 3U5T-A nrPDB 225 2e-59 3T7C-A nrPDB 223 4e-59 1X1T-A nrPDB 223 4e-59 4CQM-B nrPDB 223 5e-59 3RWB-A nrPDB 223 5e-59 1UZM-A nrPDB 223 6e-59 4HP8-A nrPDB 222 9e-59 1DOH-A nrPDB 221 3e-58 1K2W-A nrPDB 221 3e-58 3UF0-A nrPDB 219 7e-58 2CFC-A nrPDB 219 8e-58 3U4C-A nrPDB 218 2e-57 3OIG-A nrPDB 218 2e-57 4FC7-A nrPDB 215 2e-56 2HSD-A nrPDB 215 2e-56 4E6P-A nrPDB 214 3e-56 5EJ2-A nrPDB 214 3e-56 5YCX-A nrPDB 213 6e-56 5B1Y-A nrPDB 213 7e-56 3V8B-A nrPDB 213 7e-56 2YW9-A nrPDB 212 1e-55 5TF4-A nrPDB 211 2e-55 4ZJU-A nrPDB 211 3e-55 3D3W-A nrPDB 211 3e-55 2B4Q-A nrPDB 210 5e-55 3GDF-A nrPDB 210 6e-55 5KOI-A nrPDB 210 6e-55 3K2E-A nrPDB 209 1e-54 5JY1-A nrPDB 208 1e-54 3GRK-A nrPDB 207 3e-54 4NR0-A nrPDB 207 4e-54 1HXH-A nrPDB 207 4e-54 3A28-C nrPDB 206 6e-54 4AVY-A nrPDB 206 9e-54 1CYD-A nrPDB 205 1e-53 3UN1-A nrPDB 205 2e-53 5CFZ-A nrPDB 205 2e-53 1H5Q-A nrPDB 203 7e-53 2FWM-X nrPDB 203 8e-53 2AG5-A nrPDB 202 9e-53 4JQC-A nrPDB 202 1e-52 4TRR-A nrPDB 201 2e-52 5JS6-A nrPDB 199 9e-52 4M89-A nrPDB 199 1e-51 5I9N-A nrPDB 198 2e-51 4ALL-A nrPDB 198 2e-51 5O3Z-A nrPDB 197 4e-51 4EGF-A nrPDB 195 1e-50 3ZV3-A nrPDB 191 2e-49 4NK4-A nrPDB 191 3e-49 4RGB-A nrPDB 191 3e-49 4J3F-A nrPDB 188 2e-48 3PXX-A nrPDB 188 2e-48 4CR6-A nrPDB 187 4e-48 2BGM-A nrPDB 187 4e-48 1BDB-A nrPDB 186 8e-48 2X9N-A nrPDB 184 3e-47 1W73-A nrPDB 184 3e-47 2GDZ-A nrPDB 184 4e-47 4DA9-A nrPDB 183 7e-47 3OML-A nrPDB 181 2e-46 4GKB-A nrPDB 181 3e-46 2PD3-A nrPDB 179 1e-45 2O23-A nrPDB 176 8e-45 5IZ4-A nrPDB 175 2e-44 1E3W-A nrPDB 174 2e-44 1P33-A nrPDB 172 1e-43 2QHX-A nrPDB 172 2e-43 2BFA-A nrPDB 171 2e-43 3RKU-A nrPDB 166 1e-41 2NWQ-A nrPDB 160 5e-40 3PPI-A nrPDB 160 6e-40 5ILO-A nrPDB 151 3e-37 2HRB-A nrPDB 148 2e-36 4DRY-A nrPDB 145 2e-35 1ENP-A nrPDB 143 7e-35 2O2S-A nrPDB 141 2e-34 5PGZ-A nrPDB 140 7e-34 3DWF-A nrPDB 139 1e-33 3UCF-A nrPDB 138 2e-33 3KZV-A nrPDB 136 1e-32 1N5D-A nrPDB 134 4e-32 3E9N-A nrPDB 133 1e-31 3BHI-A nrPDB 133 1e-31 3U9L-A nrPDB 126 1e-29 2PTG-A nrPDB 124 3e-29 2DKN-A nrPDB 123 8e-29 5L51-A nrPDB 122 1e-28 1FJH-A nrPDB 116 1e-26 3O26-A nrPDB 115 2e-26 5LCX-A nrPDB 111 4e-25 4Z3K-A nrPDB 110 7e-25 4HWK-A nrPDB 109 2e-24 3ORF-A nrPDB 82 2e-16 Sequences not found previously or not previously below threshold: 4Q9N-A nrPDB 143 6e-35 1A27-A nrPDB 134 3e-32 6CGE-A nrPDB 134 5e-32 2NTV-A nrPDB 129 2e-30 4OYR-A nrPDB 125 1e-29 4HBG-A nrPDB 122 9e-29 3F4B-A nrPDB 121 4e-28 2O2Y-A nrPDB 107 3e-24 1SNY-A nrPDB 106 8e-24 1B15-A nrPDB 101 4e-22 1MG5-A nrPDB 99 2e-21 1OAA-A nrPDB 97 6e-21 5WQO-A nrPDB 95 3e-20 5TQV-A nrPDB 90 8e-19 3SLK-A nrPDB 71 4e-13 4LIS-A nrPDB 66 2e-11 2PK3-A nrPDB 64 7e-11 1OOE-A nrPDB 59 2e-09 1UDA-A nrPDB 55 3e-08 6BWL-A nrPDB 55 3e-08 1DIR-A nrPDB 54 5e-08 3RFT-A nrPDB 50 9e-07 3ENK-A nrPDB 50 1e-06 1VL0-A nrPDB 49 2e-06 3SXP-A nrPDB 49 2e-06 5B6K-A nrPDB 49 2e-06 1I3M-A nrPDB 48 4e-06 2GN9-A nrPDB 48 4e-06 2Q1W-A nrPDB 46 1e-05 4PVC-A nrPDB 46 2e-05 1RKX-A nrPDB 45 4e-05 6ACF-A nrPDB 45 4e-05 1Z45-A nrPDB 44 4e-05 4G5H-A nrPDB 44 5e-05 1GY8-A nrPDB 44 6e-05 2PZM-A nrPDB 43 1e-04 1OC2-A nrPDB 42 2e-04 5N2I-A nrPDB 42 3e-04 3HFS-A nrPDB 42 3e-04 1LU9-A nrPDB 41 4e-04 4KTT-E nrPDB 41 4e-04 6GCS-E nrPDB 41 4e-04 1WVG-A nrPDB 41 4e-04 3VPX-A nrPDB 41 6e-04 3SC6-A nrPDB 41 7e-04 1R66-A nrPDB 40 8e-04 2NNL-D nrPDB 40 9e-04 4EUF-A nrPDB 40 0.001 1DB3-A nrPDB 39 0.002 2Z95-A nrPDB 39 0.003 2GGS-A nrPDB 38 0.003 3OND-A nrPDB 38 0.003 6DEB-A nrPDB 38 0.003 4J2O-A nrPDB 38 0.004 1BXK-A nrPDB 38 0.005 1KEU-A nrPDB 37 0.005 1ZZE-A nrPDB 37 0.006 5INT-A nrPDB 37 0.007 5JXW-A nrPDB 37 0.007 6G2J-P nrPDB 37 0.007 4K28-A nrPDB 37 0.008 4KUG-A nrPDB 37 0.008 3LK7-A nrPDB 37 0.009 4EJ0-A nrPDB 37 0.010 2GAS-A nrPDB 37 0.010 5K1S-A nrPDB 36 0.011 6ACQ-A nrPDB 36 0.014 4WPG-A nrPDB 36 0.020 5YWN-A nrPDB 36 0.020 2EXX-A nrPDB 36 0.024 1E3J-A nrPDB 35 0.031 4J6F-A nrPDB 35 0.032 5GUP-L nrPDB 35 0.035 2Q4B-A nrPDB 35 0.035 4KDR-A nrPDB 35 0.040 4A10-A nrPDB 35 0.041 3A14-A nrPDB 35 0.041 6C6P-A nrPDB 34 0.044 3PVZ-A nrPDB 34 0.044 3NJ4-A nrPDB 34 0.044 4KDC-A nrPDB 34 0.045 1GPJ-A nrPDB 34 0.062 1RPN-A nrPDB 34 0.081 2C54-A nrPDB 34 0.090 2C20-A nrPDB 33 0.097 3CT4-A nrPDB 33 0.100 1O89-A nrPDB 33 0.10 3X2F-A nrPDB 33 0.12 4BKP-A nrPDB 33 0.13 1VPD-A nrPDB 33 0.14 3R0Q-C nrPDB 33 0.16 3K30-A nrPDB 32 0.16 3N58-A nrPDB 32 0.17 4G2N-A nrPDB 32 0.18 2VN8-A nrPDB 32 0.19 3HZZ-A nrPDB 32 0.19 5UZH-A nrPDB 32 0.20 5ENV-A nrPDB 32 0.20 4PZE-A nrPDB 32 0.23 6BI4-A nrPDB 32 0.23 5A3V-A nrPDB 32 0.23 4J90-A nrPDB 32 0.24 3PEF-A nrPDB 32 0.24 3DFZ-A nrPDB 32 0.24 6GBN-A nrPDB 32 0.27 2EER-A nrPDB 32 0.27 4B4V-A nrPDB 32 0.30 3DMF-A nrPDB 32 0.32 2X86-A nrPDB 32 0.33 6C55-A nrPDB 31 0.37 3WMX-A nrPDB 31 0.38 3K96-A nrPDB 31 0.41 4EJ6-A nrPDB 31 0.42 1JAY-A nrPDB 31 0.46 5F5N-A nrPDB 31 0.48 4B4O-A nrPDB 31 0.53 4B3J-A nrPDB 31 0.53 1IE3-A nrPDB 31 0.53 1EQ2-A nrPDB 31 0.56 3HDH-A nrPDB 31 0.58 5TC4-A nrPDB 31 0.60 5JE5-A nrPDB 31 0.61 1QQV-A nrPDB 31 0.62 1F14-A nrPDB 31 0.62 5BUT-A nrPDB 31 0.69 2HK7-A nrPDB 31 0.70 1V8B-A nrPDB 31 0.70 2OHJ-A nrPDB 31 0.72 3BIC-A nrPDB 31 0.72 2HMT-A nrPDB 31 0.73 4E0B-A nrPDB 31 0.79 3ZU2-A nrPDB 30 0.91 5U9C-A nrPDB 30 0.99 4A5O-A nrPDB 30 1.0 7REQ-A nrPDB 30 1.1 1ZDL-A nrPDB 30 1.1 5GXF-A nrPDB 30 1.1 3H9U-A nrPDB 30 1.1 6BII-A nrPDB 30 1.2 1YXY-A nrPDB 30 1.2 4QPN-A nrPDB 30 1.3 1YB5-A nrPDB 30 1.3 3R9I-A nrPDB 30 1.3 4UUP-A nrPDB 30 1.4 4WOK-A nrPDB 30 1.4 3DQQ-A nrPDB 29 1.4 2WEK-A nrPDB 29 1.4 1TLL-A nrPDB 29 1.4 2OWO-A nrPDB 29 1.5 4WLE-A nrPDB 29 1.5 5EGS-A nrPDB 29 1.6 2DFV-A nrPDB 29 1.6 1ZCJ-A nrPDB 29 1.7 6H0D-A nrPDB 29 1.8 3H0K-A nrPDB 29 1.9 2ZJ1-A nrPDB 29 1.9 3OPY-A nrPDB 29 2.0 3ZWA-A nrPDB 29 2.0 1MLD-A nrPDB 29 2.0 1EDZ-A nrPDB 29 2.0 3IP1-A nrPDB 29 2.1 5IOB-A nrPDB 29 2.1 3JYO-A nrPDB 29 2.1 2XHZ-A nrPDB 29 2.2 3ZXS-A nrPDB 29 2.2 6APE-A nrPDB 29 2.2 4XRR-A nrPDB 29 2.4 4FQ8-A nrPDB 29 2.4 3DC2-A nrPDB 29 2.4 5H02-A nrPDB 29 2.5 3FBG-A nrPDB 29 2.5 1U3W-A nrPDB 29 2.5 3F6T-A nrPDB 29 2.6 2YQ5-A nrPDB 29 2.7 3E23-A nrPDB 29 2.9 3K6J-A nrPDB 29 2.9 1SQG-A nrPDB 29 3.0 2VCY-A nrPDB 28 3.3 5XF9-B nrPDB 28 3.4 5G1T-A nrPDB 28 3.4 3HG7-A nrPDB 28 3.4 4GBJ-A nrPDB 28 3.5 2V6G-A nrPDB 28 3.6 2P0Y-A nrPDB 28 3.7 4IYO-A nrPDB 28 4.1 1NHQ-A nrPDB 28 4.1 2BC1-A nrPDB 28 4.1 3RUE-A nrPDB 28 4.2 2IY3-A nrPDB 28 4.2 4BM5-A nrPDB 28 4.4 6H5E-B nrPDB 28 4.5 6F4U-A nrPDB 28 4.5 6F02-A nrPDB 28 4.5 3UOG-A nrPDB 28 4.5 3D64-A nrPDB 28 4.6 4N5F-A nrPDB 28 4.7 4MM1-A nrPDB 28 4.7 3GFB-A nrPDB 28 4.8 4OMU-A nrPDB 28 4.9 4R16-A nrPDB 28 5.0 2D0I-A nrPDB 28 5.0 3VR3-A nrPDB 28 5.0 4V6H-A nrPDB 28 5.0 3S8M-A nrPDB 28 5.1 2FFH-A nrPDB 27 5.4 2RIR-A nrPDB 27 5.6 2C2Y-A nrPDB 27 6.1 4OFX-A nrPDB 27 6.2 3L07-A nrPDB 27 6.2 5O2A-B nrPDB 27 6.7 5DZS-A nrPDB 27 6.7 5MH6-A nrPDB 27 7.1 1RJ9-B nrPDB 27 7.2 5GSN-A nrPDB 27 7.4 5KIA-A nrPDB 27 7.5 3TX2-A nrPDB 27 8.3 1EO7-A nrPDB 27 8.3 4A26-A nrPDB 27 8.7 3MFY-A nrPDB 27 8.8 5F8E-A nrPDB 27 8.8 4BKO-A nrPDB 27 9.1 3PC3-A nrPDB 27 9.5 2EFY-A nrPDB 27 9.6 >1AHH-A nrPDB Length = 255 Score = 324 bits (831), Expect = 2e-89, Method: Composition-based stats. Identities = 255/255 (100%), Positives = 255/255 (100%) Query: 1 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG 60 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG Sbjct: 1 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG 60 Query: 61 QAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVF 120 QAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVF Sbjct: 61 QAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVF 120 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK Sbjct: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 Query: 181 NIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVS 240 NIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVS Sbjct: 181 NIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVS 240 Query: 241 GQILTVSGGGVQELN 255 GQILTVSGGGVQELN Sbjct: 241 GQILTVSGGGVQELN 255 >2PNF-A nrPDB Length = 248 Score = 292 bits (748), Expect = 1e-79, Method: Composition-based stats. Identities = 80/248 (32%), Positives = 146/248 (58%), Gaps = 3/248 (1%) Query: 5 DNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQ-QLGGQAF 63 ++L GK +++TG+ GIG+ IA A+AG++V+++ + + A V +EI + G +A Sbjct: 1 MEIKLQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAH 60 Query: 64 ACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSF 122 ++ SE+ ++ + + + +DILVNNAG K F M + D+ ++N+ Sbjct: 61 GVEMNLLSEESINKAFEEIYNLVDGIDILVNNAGITRDKLFLRMSLLDWEEVLKVNLTGT 120 Query: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182 F ++Q +M K G I+ I+S+ N+ +Y+++KA +++A +L +N+ Sbjct: 121 FLVTQNSLRKMIKQRWGRIVNISSVVGFTGNVGQVNYSTTKAGLIGFTKSLAKELAPRNV 180 Query: 183 RVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQ 242 VN +APG I TD +V++ EI+QK + P+ R G P+++AN LFLCS AS+++G+ Sbjct: 181 LVNAVAPGFIETDMT-AVLSEEIKQKYKEQIPLGRFGSPEEVANVVLFLCSELASYITGE 239 Query: 243 ILTVSGGG 250 ++ V+GG Sbjct: 240 VIHVNGGM 247 >4JRO-A nrPDB Length = 271 Score = 286 bits (733), Expect = 5e-78, Method: Composition-based stats. Identities = 81/252 (32%), Positives = 130/252 (51%), Gaps = 3/252 (1%) Query: 2 FNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDI-NADAANHVVDEIQQLGG 60 F S+ + L GK A++TG GIG++IAI A GA++ + + +AA + + G Sbjct: 20 FQSNAMTLQGKVAVVTGGSRGIGRDIAINLAKEGANIFFNYNGSPEAAEETAKLVAEHGV 79 Query: 61 QAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNV 119 + A + ++ +++ A AI + G+VDILVNNAG M ++ +N+ Sbjct: 80 EVEAMKANVAIAEDVDAFFKQAIERFGRVDILVNNAGITRDNLLMRMKEDEWDDVININL 139 Query: 120 FSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGE 179 F ++ V+ M K G I+ + S+ N +Y +SKA L + A +L Sbjct: 140 KGTFLCTKAVSRTMMKQRAGKIINMASVVGLIGNAGQANYVASKAGVIGLTKTTARELAP 199 Query: 180 KNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 + I VN +APG I TD + + ++ ML P+ G +DIANA LFL S A+ ++ Sbjct: 200 RGINVNAVAPGFITTDMTDKL-DEKTKEAMLAQIPLGAYGTTEDIANAVLFLASDASKYI 258 Query: 240 SGQILTVSGGGV 251 +GQ L+V GG V Sbjct: 259 TGQTLSVDGGMV 270 >2UVD-A nrPDB Length = 246 Score = 279 bits (715), Expect = 6e-76, Method: Composition-based stats. Identities = 91/245 (37%), Positives = 132/245 (53%), Gaps = 3/245 (1%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDI-NADAANHVVDEIQQLGGQAFACRC 67 L GK A++TGA GIG+ IAI A GA+VVV+ N AN VVDEI++LG A A R Sbjct: 2 LKGKVALVTGASRGIGRAIAIDLAKQGANVVVNYAGNEQKANEVVDEIKKLGSDAIAVRA 61 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLS 126 D+ + ++++ + + G+VDILVNNAG M ++ N+ F + Sbjct: 62 DVANAEDVTNMVKQTVDVFGQVDILVNNAGVTKDNLLMRMKEEEWDTVINTNLKGVFLCT 121 Query: 127 QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNG 186 + V+ M + G I+ I S+ N +Y ++KA L + A +L +NI VN Sbjct: 122 KAVSRFMMRQRHGRIVNIASVVGVTGNPGQANYVAAKAGVIGLTKTSAKELASRNITVNA 181 Query: 187 IAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTV 246 IAPG I TD V+ I+ +ML+ P + G+ QDIANA F S + +++GQ L V Sbjct: 182 IAPGFIATDMTD-VLDENIKAEMLKLIPAAQFGEAQDIANAVTFFASDQSKYITGQTLNV 240 Query: 247 SGGGV 251 GG V Sbjct: 241 DGGMV 245 >3OSU-A nrPDB Length = 246 Score = 279 bits (713), Expect = 1e-75, Method: Composition-based stats. Identities = 77/246 (31%), Positives = 134/246 (54%), Gaps = 4/246 (1%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDI-NADAANHVVDEIQQLGGQAFAC 65 +++ K A++TGA GIG+ IA+ A G +V V+ + + A VV+EI+ G +FA Sbjct: 1 MKMT-KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAI 59 Query: 66 RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFH 124 + ++ E+ A+ +S+ G +D+LVNNAG M ++ + N+ F+ Sbjct: 60 QANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFN 119 Query: 125 LSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 Q P+M + G I+ ++S+ N +Y ++KA L ++ A +L + I V Sbjct: 120 CIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITV 179 Query: 185 NGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQIL 244 N +APG I++D ++ + E++++ML P+ R GQ DIAN FL S A +++GQ + Sbjct: 180 NAVAPGFIVSDMTDAL-SDELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITGQTI 238 Query: 245 TVSGGG 250 V+GG Sbjct: 239 HVNGGM 244 >2HQ1-A nrPDB Length = 247 Score = 275 bits (705), Expect = 9e-75, Method: Composition-based stats. Identities = 74/247 (29%), Positives = 131/247 (53%), Gaps = 3/247 (1%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINAD-AANHVVDEIQQLGGQAFAC 65 ++L GK AI+TG+ G+GK IA GA++V++ A + + +E + G Sbjct: 1 MQLKGKTAIVTGSSRGLGKAIAWKLGNMGANIVLNGSPASTSLDATAEEFKAAGINVVVA 60 Query: 66 RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKP-FDMPMADFRRAYELNVFSFFH 124 + D+ + +++ + A+ G++DILVNNAG M D+ N+ S + Sbjct: 61 KGDVKNPEDVENMVKTAMDAFGRIDILVNNAGITRDTLMLKMSEKDWDDVLNTNLKSAYL 120 Query: 125 LSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 ++ V+ M K G I+ ITS+A N +YA+SKA +++A + K I Sbjct: 121 CTKAVSKIMLKQKSGKIINITSIAGIIGNAGQANYAASKAGLIGFTKSIAKEFAAKGIYC 180 Query: 185 NGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQIL 244 N +APG I TD V+ ++++ L + P++R G P+++AN FL S +++++GQ++ Sbjct: 181 NAVAPGIIKTDMTD-VLPDKVKEMYLNNIPLKRFGTPEEVANVVGFLASDDSNYITGQVI 239 Query: 245 TVSGGGV 251 + GG V Sbjct: 240 NIDGGLV 246 >2C07-A nrPDB Length = 285 Score = 274 bits (702), Expect = 2e-74, Method: Composition-based stats. Identities = 77/241 (31%), Positives = 137/241 (56%), Gaps = 2/241 (0%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDI 69 + K A++TGAG GIG+EIA A + + V+ + + VVDEI+ G ++ D+ Sbjct: 43 ENKVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKSFGYESSGYAGDV 102 Query: 70 TSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQL 128 + ++E+S + + +++ VDILVNNAG F M ++ N+ S F+++Q Sbjct: 103 SKKEEISEVINKILTEHKNVDILVNNAGITRDNLFLRMKNDEWEDVLRTNLNSLFYITQP 162 Query: 129 VAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIA 188 ++ M N G I+ I+S+ N+ +Y+SSKA +++A +L +NI VN IA Sbjct: 163 ISKRMINNRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKELASRNITVNAIA 222 Query: 189 PGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSG 248 PG I +D I+ +I++ ++ + P R+G P+++AN A FL S + +++G++ + G Sbjct: 223 PGFISSDMTDK-ISEQIKKNIISNIPAGRMGTPEEVANLACFLSSDKSGYINGRVFVIDG 281 Query: 249 G 249 G Sbjct: 282 G 282 >3RSH-A nrPDB Length = 251 Score = 270 bits (690), Expect = 6e-73, Method: Composition-based stats. Identities = 82/248 (33%), Positives = 126/248 (50%), Gaps = 5/248 (2%) Query: 4 SDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAF 63 S + L+GK A++TGA GIGK IA A GA V+ + + A + D + G Sbjct: 5 SQFMNLEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGK--- 61 Query: 64 ACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSF 122 ++T+ + + A+ + G VDILVNNAG M ++ E N+ S Sbjct: 62 GMALNVTNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSI 121 Query: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182 F LS+ V M K G I+ + S+ N +YA++KA ++MA ++ + + Sbjct: 122 FRLSKAVLRGMMKKRQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVASRGV 181 Query: 183 RVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQ 242 VN +APG I TD K++ E L P RLG P++IA+A FL SP A++++G+ Sbjct: 182 TVNTVAPGFIETDMTKAL-NDEQRTATLAQVPAGRLGDPREIASAVAFLASPEAAYITGE 240 Query: 243 ILTVSGGG 250 L V+GG Sbjct: 241 TLHVNGGM 248 >3LYL-A nrPDB Length = 247 Score = 264 bits (676), Expect = 2e-71, Method: Composition-based stats. Identities = 74/245 (30%), Positives = 127/245 (51%), Gaps = 2/245 (0%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 + L+ K A++TGA GIG E+A A+ GA+VV + + +A + +++ G +A Sbjct: 1 MSLNEKVALVTGASRGIGFEVAHALASKGATVVGTATSQASAEKFENSMKEKGFKARGLV 60 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHL 125 +I+ + + ++ +DILVNNAG M +++ N+ S F + Sbjct: 61 LNISDIESIQNFFAEIKAENLAIDILVNNAGITRDNLMMRMSEDEWQSVINTNLSSIFRM 120 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 S+ M K G I++I S+ N T+Y ++KA +++A+++ +NI VN Sbjct: 121 SKECVRGMMKKRWGRIISIGSVVGSAGNPGQTNYCAAKAGVIGFSKSLAYEVASRNITVN 180 Query: 186 GIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILT 245 +APG I TD + T E + + P ++G+P+DIA A FL S A +++GQ L Sbjct: 181 VVAPGFIATDMTDKL-TDEQKSFIATKIPSGQIGEPKDIAAAVAFLASEEAKYITGQTLH 239 Query: 246 VSGGG 250 V+GG Sbjct: 240 VNGGM 244 >3WOH-A nrPDB Length = 251 Score = 263 bits (673), Expect = 5e-71, Method: Composition-based stats. Identities = 76/244 (31%), Positives = 129/244 (52%), Gaps = 5/244 (2%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADA-ANHVVDEIQQLGGQAFACRC 67 L GK A++TG G+G+ +A+ A GA+V + ++ D+ A EI++LGG A + RC Sbjct: 9 LSGKVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLGGTARSYRC 68 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLS 126 D++ ++++ + LG VDILVNNAG + D+ N+ F Sbjct: 69 DVSDAEQVTRCVKAVTADLGPVDILVNNAGIIRDGLAASIKDEDYDAVMNTNLKGAFLFI 128 Query: 127 QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNG 186 + + G I+ I+S++ + +YAS+KA L +++A +L E+N+R N Sbjct: 129 KACYFGFIRKRSGSIINISSVSGVFGSAGQANYASAKAGLIGLTKSIAKELAERNVRCNA 188 Query: 187 IAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTV 246 +APG I TD + ++ K L P+RR G+P ++A FL +S+++GQ++ V Sbjct: 189 VAPGLIATDMTQDLVDD---SKRLDPVPMRRFGRPDEVAGLVAFLAGDESSYITGQVVCV 245 Query: 247 SGGG 250 GG Sbjct: 246 DGGM 249 >3FTP-A nrPDB Length = 270 Score = 263 bits (673), Expect = 5e-71, Method: Composition-based stats. Identities = 81/248 (32%), Positives = 129/248 (52%), Gaps = 2/248 (0%) Query: 4 SDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAF 63 S + LD + AI+TGA GIG+ IA+ A GA V+ + A + +Q G + Sbjct: 21 SMDKTLDKQVAIVTGASRGIGRAIALELARRGAMVIGTATTEAGAEGIGAAFKQAGLEGR 80 Query: 64 ACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKP-FDMPMADFRRAYELNVFSF 122 ++ + AL + + + G +++LVNNAG + M ++ + N+ + Sbjct: 81 GAVLNVNDATAVDALVESTLKEFGALNVLVNNAGITQDQLAMRMKDDEWDAVIDTNLKAV 140 Query: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182 F LS+ V M K GG I+ ITS+ N +YA++KA + + R +A ++G + I Sbjct: 141 FRLSRAVLRPMMKARGGRIVNITSVVGSAGNPGQVNYAAAKAGVAGMTRALAREIGSRGI 200 Query: 183 RVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQ 242 VN +APG I TD K + E + + P+ RLG P+DIA+A FL SP A +++G Sbjct: 201 TVNCVAPGFIDTDMTKGL-PQEQQTALKTQIPLGRLGSPEDIAHAVAFLASPQAGYITGT 259 Query: 243 ILTVSGGG 250 L V+GG Sbjct: 260 TLHVNGGM 267 >1Q7C-A nrPDB Length = 244 Score = 262 bits (671), Expect = 9e-71, Method: Composition-based stats. Identities = 78/245 (31%), Positives = 128/245 (52%), Gaps = 5/245 (2%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 + +GK A++TGA GIG+ IA T A GA V+ + + + A + D + G Sbjct: 1 MNFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGK---GLM 57 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHL 125 ++T + ++ + ++ G+VDILVNNAG M ++ E N+ S F L Sbjct: 58 LNVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFRL 117 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 S+ V M K G I+TI S+ N ++A++KA +++A ++ + I VN Sbjct: 118 SKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANFAAAKAGLIGFSKSLAREVASRGITVN 177 Query: 186 GIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILT 245 +APG I TD +++ + + +L P RLG Q+IANA FL S A++++G+ L Sbjct: 178 VVAPGFIETDMTRAL-SDDQRAGILAQVPAGRLGGAQEIANAVAFLASDEAAYITGETLH 236 Query: 246 VSGGG 250 V+GG Sbjct: 237 VNGGM 241 >3EMK-A nrPDB Length = 246 Score = 262 bits (669), Expect = 1e-70, Method: Composition-based stats. Identities = 74/247 (29%), Positives = 127/247 (51%), Gaps = 5/247 (2%) Query: 5 DNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFA 64 L G+ A++TGA G+G+ IA GA V + + + E+ G + F Sbjct: 1 SMFDLTGRKALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAEL---GERIFV 57 Query: 65 CRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFF 123 +++ + + AL A ++G VDILVNNAG F M D+ +N+ S F Sbjct: 58 FPANLSDREAVKALGQKAEEEMGGVDILVNNAGITRDGLFVRMSDEDWDAVLTVNLTSVF 117 Query: 124 HLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIR 183 +L++ + M + G I+ ITS+ N +Y +SKA +++A ++ +N+ Sbjct: 118 NLTRELTHPMMRRRNGRIINITSIVGVTGNPGQANYCASKAGLIGFSKSLAQEIASRNVT 177 Query: 184 VNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQI 243 VN IAPG I + A+ + + + ++ + P++R+G DIA A ++L S A++V+GQ Sbjct: 178 VNCIAPGFIES-AMTGKLNEKQKDAIMGNIPMKRMGVGADIAAAVVYLASDEAAYVTGQT 236 Query: 244 LTVSGGG 250 L V+GG Sbjct: 237 LHVNGGM 243 >4BO1-A nrPDB Length = 269 Score = 261 bits (667), Expect = 2e-70, Method: Composition-based stats. Identities = 76/247 (30%), Positives = 126/247 (51%), Gaps = 2/247 (0%) Query: 5 DNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFA 64 ++ L GK A++TGA GIG+ IA+ GA V+ + +A A + + ++ G + Sbjct: 21 QSMSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAG 80 Query: 65 CRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFF 123 D++S++ ++A + LG+ I+VNNAG M ++ N+ S + Sbjct: 81 LVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEWFDVVNTNLNSLY 140 Query: 124 HLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIR 183 LS+ V M K G I+ I S+ N T+YA++KA R +A ++G + I Sbjct: 141 RLSKAVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAIT 200 Query: 184 VNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQI 243 VN +APG I TD + + + +L P+ RLGQ ++IA FL S A++V+G Sbjct: 201 VNAVAPGFIDTDMTREL-PEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGAT 259 Query: 244 LTVSGGG 250 + V+GG Sbjct: 260 VPVNGGM 266 >5CDY-A nrPDB Length = 244 Score = 260 bits (666), Expect = 3e-70, Method: Composition-based stats. Identities = 75/245 (30%), Positives = 123/245 (50%), Gaps = 5/245 (2%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 + +GK A++TGA GIG+ IA GA V+ + + A + + + G Sbjct: 1 MSFEGKIALVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGK---GLM 57 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHL 125 ++ + + ++ G+VDILVNNAG M +++ + N+ S F L Sbjct: 58 LNVVDPTSIDTVLATIRAEFGEVDILVNNAGITRDNLLMRMKDDEWQDIIDTNLTSVFRL 117 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 S+ V M K G I+TI S+ N +YA++KA +++A ++ + I VN Sbjct: 118 SKAVMRAMMKKRFGRIITIGSVVGTMGNAGQVNYAAAKAGVIGFSKSLAREVASRGITVN 177 Query: 186 GIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILT 245 +APG I TD +++ T + +L P RLG ++IA+A FL S AS++SG+ L Sbjct: 178 VVAPGFIETDMTRTL-TDDQRAGILAQVPANRLGDAKEIASAVAFLASDEASYISGETLH 236 Query: 246 VSGGG 250 V+GG Sbjct: 237 VNGGM 241 >3O4R-A nrPDB Length = 261 Score = 260 bits (664), Expect = 5e-70, Method: Composition-based stats. Identities = 83/249 (33%), Positives = 127/249 (51%), Gaps = 3/249 (1%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 L K A++T + GIG IA A GA VVVS + V +Q G C Sbjct: 13 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 72 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAGGGG--PKPFDMPMADFRRAYELNVFSFFHLS 126 + ++ L A+ G +DILV+NA D+ + + ++NV + ++ Sbjct: 73 VGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMT 132 Query: 127 QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNG 186 + V PEMEK GGG ++ ++S+AA + + + Y SK A L + +A +L +NIRVN Sbjct: 133 KAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNC 192 Query: 187 IAPGAILTDALKSVI-TPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILT 245 +APG I T + + E E+ M + IRRLG+P+D A FLCS AS+++G+ + Sbjct: 193 LAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVV 252 Query: 246 VSGGGVQEL 254 V GG L Sbjct: 253 VGGGTPSRL 261 >4M8S-A nrPDB Length = 248 Score = 257 bits (657), Expect = 3e-69, Method: Composition-based stats. Identities = 85/244 (34%), Positives = 125/244 (51%), Gaps = 4/244 (1%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 L GK A++TGA GIG IA T A AGA V+ + + A + + + Q GG+ + Sbjct: 6 LSGKIALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGGEGRVL--N 63 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQ 127 + + L GK+DILVNNAG M ++ ++N+ S F S+ Sbjct: 64 SAEPETVENLIADIEKTFGKLDILVNNAGITRDNLLMRMKEEEWDDIMQVNLKSVFRASK 123 Query: 128 LVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGI 187 V M K G I+ ITS+ N T+YA++KA ++MA ++G + I VN + Sbjct: 124 AVLRGMMKQRAGRIINITSVVGVMGNAGQTNYAAAKAGLIGFSKSMAREVGSRGITVNCV 183 Query: 188 APGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVS 247 APG I TD +++ E Q T + R G QDIA+A LFL S A +++GQ L V+ Sbjct: 184 APGFIDTDMTRAL-PEETRQTFTAQTALGRFGDAQDIADAVLFLASDQAKYITGQTLHVN 242 Query: 248 GGGV 251 GG + Sbjct: 243 GGML 246 >1GEE-A nrPDB Length = 261 Score = 257 bits (656), Expect = 4e-69, Method: Composition-based stats. Identities = 83/246 (33%), Positives = 134/246 (54%), Gaps = 4/246 (1%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN-ADAANHVVDEIQQLGGQAFACRC 67 L+GK +ITG+ G+GK +AI FAT A VVV+ + D AN V++EI+++GG+A A + Sbjct: 5 LEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKVGGEAIAVKG 64 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGP-KPFDMPMADFRRAYELNVFSFFHLS 126 D+T E ++ L AI + GK+D+++NNAG P +M ++D+ + + N+ F S Sbjct: 65 DVTVESDVINLVQSAIKEFGKLDVMINNAGLENPVSSHEMSLSDWNKVIDTNLTGAFLGS 124 Query: 127 QLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 + +N G ++ ++S+ + YA+SK + +A + K IRVN Sbjct: 125 REAIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVN 184 Query: 186 GIAPGAILTDA-LKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQIL 244 I PGAI T + PE + P+ +G+P++IA A +L S AS+V+G L Sbjct: 185 NIGPGAINTPINAEKFADPEQRADVESMIPMGYIGEPEEIAAVAAWLASSEASYVTGITL 244 Query: 245 TVSGGG 250 GG Sbjct: 245 FADGGM 250 >4K6F-A nrPDB Length = 255 Score = 257 bits (656), Expect = 5e-69, Method: Composition-based stats. Identities = 65/244 (26%), Positives = 124/244 (50%), Gaps = 2/244 (0%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDI-NADAANHVVDEIQQLGGQAFACRC 67 + + A++TG G+G+ ++I AG VVV+ N A+ + E+ G + A Sbjct: 9 MTKRIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNTGADRWLTEMHAAGREFHAYPV 68 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFHLS 126 D+ + + +G VDILVNNAG + ++ N+ S F+++ Sbjct: 69 DVADHDSCQQCIEKIVRDVGPVDILVNNAGITRDMTLRKLDKVNWDAVIRTNLDSVFNMT 128 Query: 127 QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNG 186 + V M + G G I+ I+S+ ++ T+YA++KA +++A ++ K + VN Sbjct: 129 KPVCDGMVERGWGRIVNISSVNGSKGSVGQTNYAAAKAGMHGFTKSLALEIARKGVTVNT 188 Query: 187 IAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTV 246 ++PG + T + ++ ++ K+L P RLG+P+++A +LCS A +V+G + + Sbjct: 189 VSPGYLATKMVTAIPQDILDTKILPQIPAGRLGKPEEVAALVAYLCSEEAGFVTGSNIAI 248 Query: 247 SGGG 250 +GG Sbjct: 249 NGGQ 252 >4IIN-A nrPDB Length = 271 Score = 257 bits (656), Expect = 5e-69, Method: Composition-based stats. Identities = 77/250 (30%), Positives = 132/250 (52%), Gaps = 3/250 (1%) Query: 2 FNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDI-NADAANHVVDEIQQLGG 60 F S+ ++ GK +ITGA GIG EIA T A+ G V ++ NA+ A+ + +E+++ G Sbjct: 20 FQSNAMQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGY 79 Query: 61 QAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKP-FDMPMADFRRAYELNV 119 +A + D SE + + G + LVNNAG K M DF + N+ Sbjct: 80 KAAVIKFDAASESDFIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNL 139 Query: 120 FSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGE 179 S F + M K+ G ++ + S+ E N+ T+Y++SK + ++ A++ Sbjct: 140 TSAFIGCREALKVMSKSRFGSVVNVASIIGERGNMGQTNYSASKGGMIAMSKSFAYEGAL 199 Query: 180 KNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 +NIR N + PG I TD ++ E++ +++ P+ RLG +++A A FL S +S++ Sbjct: 200 RNIRFNSVTPGFIETDMNANL-KDELKADYVKNIPLNRLGSAKEVAEAVAFLLSDHSSYI 258 Query: 240 SGQILTVSGG 249 +G+ L V+GG Sbjct: 259 TGETLKVNGG 268 >5ITV-A nrPDB Length = 255 Score = 255 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 73/257 (28%), Positives = 124/257 (48%), Gaps = 10/257 (3%) Query: 5 DNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFA 64 + L K +ITG +GIG F A+VVV+DI+ +V ++ + Sbjct: 1 MIMNLTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVR--KENNDRLHF 58 Query: 65 CRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFF 123 + DIT E + A+ G +D+L+NNAG P +M ++D+ + ++N+ F Sbjct: 59 VQTDITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMF 118 Query: 124 HLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIR 183 +S+ M G G I+ S+ ++ +Y +SK L ++MA D + IR Sbjct: 119 LMSKHALKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIR 178 Query: 184 VNGIAPGAILTDALKSVI-------TPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAA 236 VN + PG I T + EI+++ + P+ RLG+P++IAN LFL S + Sbjct: 179 VNCVCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRLGKPEEIANVMLFLASDLS 238 Query: 237 SWVSGQILTVSGGGVQE 253 S+++G +T GG + Sbjct: 239 SYMTGSAITADGGYTAQ 255 >2ZAT-A nrPDB Length = 260 Score = 255 bits (651), Expect = 2e-68, Method: Composition-based stats. Identities = 84/249 (33%), Positives = 127/249 (51%), Gaps = 3/249 (1%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 L+ K A++T + GIG IA A GA VVVS + + V +Q G C Sbjct: 12 LENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTVCH 71 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAGGGG--PKPFDMPMADFRRAYELNVFSFFHLS 126 + ++ L A++ G VDILV+NA D + + +NV + ++ Sbjct: 72 VGKAEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKATVLMT 131 Query: 127 QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNG 186 + V PEMEK GGG +L ++S+ A + N+ Y SK A L +N+A +L +NIRVN Sbjct: 132 KAVVPEMEKRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIRVNC 191 Query: 187 IAPGAILTDALKSVITPEIE-QKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILT 245 +APG I T+ + + + + M + IRRLG P+D A FLCS AS+++G+ + Sbjct: 192 LAPGLIKTNFSQVLWMDKARKEYMKESLRIRRLGNPEDCAGIVSFLCSEDASYITGETVV 251 Query: 246 VSGGGVQEL 254 V GG L Sbjct: 252 VGGGTASRL 260 >4RZH-A nrPDB Length = 247 Score = 253 bits (646), Expect = 7e-68, Method: Composition-based stats. Identities = 81/246 (32%), Positives = 133/246 (54%), Gaps = 7/246 (2%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDI-NADAANHVVDEIQQLGGQAFACRC 67 L + A++TGA GIGK A+ A G VVV+ ++ AA+ VV EI GG+A A + Sbjct: 4 LTAQVALVTGASRGIGKATALALAATGMKVVVNYAQSSTAADAVVAEIIANGGEAIAVQA 63 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLS 126 ++ + E+ L + K ++D+LVNNAG M + D++ +LN+ F + Sbjct: 64 NVANADEVDQLIKTTLDKFSRIDVLVNNAGITRDTLLLRMKLEDWQAVIDLNLTGVFLCT 123 Query: 127 QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNG 186 + V+ M K G I+ ITS+A N +Y+++KA + +A +L + + VN Sbjct: 124 KAVSKLMLKQKSGRIINITSVAGMMGNPGQANYSAAKAGVIGFTKTVAKELASRGVTVNA 183 Query: 187 IAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSP-AASWVSGQILT 245 +APG I TD +++ + +LQ P+ R GQP+++A FL + AA++++GQ Sbjct: 184 VAPGFIATDMTENLN----AEPILQFIPLARYGQPEEVAGTIRFLATDPAAAYITGQTFN 239 Query: 246 VSGGGV 251 V GG V Sbjct: 240 VDGGMV 245 >3EZL-A nrPDB Length = 256 Score = 252 bits (643), Expect = 1e-67, Method: Composition-based stats. Identities = 65/245 (26%), Positives = 124/245 (50%), Gaps = 3/245 (1%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVV-SDINADAANHVVDEIQQLGGQAFAC 65 + + + A +TG GIG I G VV N+ +++ + LG +A Sbjct: 9 MVMSQRIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYAS 68 Query: 66 RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFH 124 ++ D +++G++D+LVNNAG F M D++ + N+ S F+ Sbjct: 69 EGNVGDWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTREDWQAVIDTNLTSLFN 128 Query: 125 LSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 +++ V M + G G I+ I+S+ + T+Y+++KA ++A ++ K + V Sbjct: 129 VTKQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVATKGVTV 188 Query: 185 NGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQIL 244 N ++PG I TD +K+ I P++ +K++ P+RRLG P +I + +L S + + +G Sbjct: 189 NTVSPGYIGTDMVKA-IRPDVLEKIVATIPVRRLGSPDEIGSIVAWLASEESGFSTGADF 247 Query: 245 TVSGG 249 +++GG Sbjct: 248 SLNGG 252 >3F9I-A nrPDB Length = 249 Score = 251 bits (642), Expect = 2e-67, Method: Composition-based stats. Identities = 69/247 (27%), Positives = 126/247 (51%), Gaps = 9/247 (3%) Query: 6 NLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFAC 65 + L GK ++ITGA +GIG IA G+ V++S N + + + ++ Sbjct: 9 MIDLTGKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKD---NYTIE 65 Query: 66 RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKP-FDMPMADFRRAYELNVFSFFH 124 C++ +++E S L + +DILV NAG M DF + ++N+ + F Sbjct: 66 VCNLANKEECSNLISKTSN----LDILVCNAGITSDTLAIRMKDQDFDKVIDINLKANFI 121 Query: 125 LSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 L++ +M + G I+ I+S+ N +Y +SKA + +++++++ + I V Sbjct: 122 LNREAIKKMIQKRYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYEVATRGITV 181 Query: 185 NGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQIL 244 N +APG I +D + + + ++Q P+ G P+D+A A FL S AS+++GQ L Sbjct: 182 NAVAPGFIKSDMTDKL-NEKQREAIVQKIPLGTYGIPEDVAYAVAFLASNNASYITGQTL 240 Query: 245 TVSGGGV 251 V+GG + Sbjct: 241 HVNGGML 247 >3AUT-A nrPDB Length = 269 Score = 250 bits (639), Expect = 4e-67, Method: Composition-based stats. Identities = 70/248 (28%), Positives = 122/248 (49%), Gaps = 4/248 (1%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN-ADAANHVVDEIQQLGGQAFACRC 67 L K +ITG G+G+ +A+ F A VV++ N + A E+++ GGQA + Sbjct: 13 LKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQAIIVQG 72 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKP-FDMPMADFRRAYELNVFSFFHLS 126 D+T E+++ L AI + G +D+++NNAG P P ++ + ++ + + N+ F S Sbjct: 73 DVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGAFLGS 132 Query: 127 QLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 + +N G ++ ++S+ YA+SK + +A + K IRVN Sbjct: 133 REAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVN 192 Query: 186 GIAPGAILTDA-LKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQIL 244 I PGA+ T + P + P+ +G+P+++A A FL S AS+V+G L Sbjct: 193 NIGPGAMNTPINAEKFADPVQRADVESMIPMGYIGKPEEVAAVAAFLASSQASYVTGITL 252 Query: 245 TVSGGGVQ 252 GG + Sbjct: 253 FADGGMTK 260 >3GRP-A nrPDB Length = 266 Score = 250 bits (639), Expect = 4e-67, Method: Composition-based stats. Identities = 70/248 (28%), Positives = 124/248 (50%), Gaps = 5/248 (2%) Query: 4 SDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAF 63 +L G+ A++TGA GIG+ IA F GA V + D + LG F Sbjct: 20 GSMFKLTGRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIA---ADLGKDVF 76 Query: 64 ACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSF 122 +++ + + LA+ A ++ +DILVNNAG F M D+ +N+ + Sbjct: 77 VFSANLSDRKSIKQLAEVAEREMEGIDILVNNAGITRDGLFVRMQDQDWDDVLAVNLTAA 136 Query: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182 L++ + M + G I+ ITS+ N T+Y ++KA + +A ++ +NI Sbjct: 137 STLTRELIHSMMRRRYGRIINITSIVGVVGNPGQTNYCAAKAGLIGFSKALAQEIASRNI 196 Query: 183 RVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQ 242 VN IAPG I + + + ++ ++ P++R+G ++IA A ++L S A++++GQ Sbjct: 197 TVNCIAPGFIKSAMTDKL-NEKQKEAIMAMIPMKRMGIGEEIAFATVYLASDEAAYLTGQ 255 Query: 243 ILTVSGGG 250 L ++GG Sbjct: 256 TLHINGGM 263 >2EW8-A nrPDB Length = 249 Score = 250 bits (639), Expect = 4e-67, Method: Composition-based stats. Identities = 92/250 (36%), Positives = 132/250 (52%), Gaps = 8/250 (3%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 RL K A+ITG GIG+ IA FA GA + ++D+ A I+ LG + +C Sbjct: 4 RLKDKLAVITGGANGIGRAIAERFAVEGADIAIADLVP--APEAEAAIRNLGRRVLTVKC 61 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFHLS 126 D++ ++ A IS G+ DILVNNAG PFD + +++ +E+NV S F ++ Sbjct: 62 DVSQPGDVEAFGKQVISTFGRCDILVNNAGIYPLIPFDELTFEQWKKTFEINVDSGFLMA 121 Query: 127 QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNG 186 + P M++NG G I+ +TS K T Y S+KAA R +A DLG+ I VN Sbjct: 122 KAFVPGMKRNGWGRIINLTSTTYWLKIEAYTHYISTKAANIGFTRALASDLGKDGITVNA 181 Query: 187 IAPGAILTDALKS---VITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQI 243 IAP + T ++ ++ MLQ P RL P D+ AA FL S AS+++GQ Sbjct: 182 IAPSLVRTATTEASALSAMFDVLPNMLQAIP--RLQVPLDLTGAAAFLASDDASFITGQT 239 Query: 244 LTVSGGGVQE 253 L V GG V+ Sbjct: 240 LAVDGGMVRH 249 >1AE1-A nrPDB Length = 273 Score = 250 bits (638), Expect = 6e-67, Method: Composition-based stats. Identities = 80/259 (30%), Positives = 130/259 (50%), Gaps = 10/259 (3%) Query: 1 MFNSDN---LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQ 57 M N +N L G A++TG GIG I A GA V N + ++ ++ Sbjct: 8 MMNCNNEGRWSLKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWRE 67 Query: 58 LGGQAFACRCDITSEQELSALADFAISKL-GKVDILVNNAGGGGPKPF-DMPMADFRRAY 115 G CD+ S E L GK++ILVNNAG K D D+ Sbjct: 68 KGLNVEGSVCDLLSRTERDKLMQTVAHVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIM 127 Query: 116 ELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAF 175 N + +HLSQ+ P ++ + G ++ ++S+A + +++ Y++SK A + + +++A Sbjct: 128 GTNFEAAYHLSQIAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLAC 187 Query: 176 DLGEKNIRVNGIAPGAILTDALKSVI-----TPEIEQKMLQHTPIRRLGQPQDIANAALF 230 + + NIRVN +APG ILT +++ I E + TP+ R G+PQ+++ F Sbjct: 188 EWAKDNIRVNSVAPGVILTPLVETAIKKNPHQKEEIDNFIVKTPMGRAGKPQEVSALIAF 247 Query: 231 LCSPAASWVSGQILTVSGG 249 LC PAAS+++GQI+ GG Sbjct: 248 LCFPAASYITGQIIWADGG 266 >2CDH-G nrPDB Length = 244 Score = 249 bits (636), Expect = 1e-66, Method: Composition-based stats. Identities = 81/240 (33%), Positives = 127/240 (52%), Gaps = 4/240 (1%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSD-INADAANHVVDEIQQLGGQAFACRCDITS 71 ++TGA GIGK IA++ AG V+V+ +A AA V +I+ GGQA D++ Sbjct: 3 VVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKAAEEVSKQIEAYGGQAITFGGDVSK 62 Query: 72 EQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQLVA 130 E ++ A+ AI G +D++VNNAG M + + +LN+ F +Q Sbjct: 63 EADVEAMMKTAIDAWGTIDVVVNNAGITRDTLLIRMKKSQWDEVIDLNLTGVFLCTQAAT 122 Query: 131 PEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPG 190 M K G I+ I S+ NI +YA++KA + A + +NI VN + PG Sbjct: 123 KIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNINVNVVCPG 182 Query: 191 AILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLC-SPAASWVSGQILTVSGG 249 I +D + + ++E+K+L P+ R GQP+++A FL SPAAS+++GQ T+ GG Sbjct: 183 FIASDMT-AKLGEDMEKKILGTIPLGRTGQPENVAGLVEFLALSPAASYITGQAFTIDGG 241 >4DMM-A nrPDB Length = 269 Score = 248 bits (633), Expect = 2e-66, Method: Composition-based stats. Identities = 79/249 (31%), Positives = 127/249 (51%), Gaps = 7/249 (2%) Query: 6 NLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFAC 65 L L + A++TGA GIG+ IA+ A AGA V V+ ++ A V G Sbjct: 23 ALPLTDRIALVTGASRGIGRAIALELAAAGAKVAVNYASSAGAADEVVAAIAAAGGEAFA 82 Query: 66 -RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFF 123 + D++ E E+ AL I + G++D+LVNNAG M D++ +LN+ F Sbjct: 83 VKADVSQESEVEALFAAVIERWGRLDVLVNNAGITRDTLLLRMKRDDWQSVLDLNLGGVF 142 Query: 124 HLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIR 183 S+ A M K G I+ I S+ E N +Y+++KA L + +A +L + I Sbjct: 143 LCSRAAAKIMLKQRSGRIINIASVVGEMGNPGQANYSAAKAGVIGLTKTVAKELASRGIT 202 Query: 184 VNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSP-AASWVSGQ 242 VN +APG I TD + +K+L+ P+ R G+ ++A FL + AA++++GQ Sbjct: 203 VNAVAPGFIATDMTSEL----AAEKLLEVIPLGRYGEAAEVAGVVRFLAADPAAAYITGQ 258 Query: 243 ILTVSGGGV 251 ++ + GG V Sbjct: 259 VINIDGGLV 267 >4NBT-A nrPDB Length = 240 Score = 247 bits (632), Expect = 2e-66, Method: Composition-based stats. Identities = 88/246 (35%), Positives = 130/246 (52%), Gaps = 13/246 (5%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 +L+GK A+ITG G+G+ IA+ +A GA V+ D+ + Sbjct: 3 KLEGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDLGD---------LTYSHPNVEGMYL 53 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFHLS 126 ++T + I K GK+DILVNNAG M A + ++N+ F+L+ Sbjct: 54 NVTDVTGVEKFYQSVIDKYGKIDILVNNAGITKDAMTRKMTEAQWDAVIDVNLKGVFNLT 113 Query: 127 QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLG--EKNIRV 184 +LV P+M+ NG G I+ I+S+ NI +YA++KA L A + N+RV Sbjct: 114 RLVGPQMQTNGYGSIINISSVVGVFGNIGQANYAATKAGVIGLTMTWAKEFALKGANVRV 173 Query: 185 NGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQIL 244 N IAPG I+TD LK+V ++ K T + RLGQP++IA ALFL S AS+V+GQ + Sbjct: 174 NAIAPGYIMTDILKTV-PQDLLDKFAALTMLNRLGQPEEIAKVALFLASDDASYVTGQTI 232 Query: 245 TVSGGG 250 V+GG Sbjct: 233 NVNGGM 238 >6NRP-A nrPDB Length = 263 Score = 245 bits (627), Expect = 1e-65, Method: Composition-based stats. Identities = 72/243 (29%), Positives = 130/243 (53%), Gaps = 7/243 (2%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADA-ANHVVDEIQQLGGQAFACRCDIT 70 + ++TG+ GIGK IA+ A AG V V + A A VV EIQ LG + D+ Sbjct: 25 RRILVTGSSRGIGKAIALQLAKAGFDVTVHARSRQAEAEQVVQEIQALGQNSHYLMFDVN 84 Query: 71 SEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFHLSQ-L 128 Q + + + + + G +V NAG F + D+ ++ F+++ + L Sbjct: 85 ERQTVQQILEQDVEQHGGFYGVVLNAGLTHDGAFPALTDQDWDEVISTSLDGFYNVLKPL 144 Query: 129 VAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIA 188 + P + GG I+T++S++ N +Y+++KA + +A +L ++ I VN +A Sbjct: 145 IMPMIHLRKGGRIVTLSSVSGIMGNRGQVNYSAAKAGLIGATKALALELAKRKITVNCVA 204 Query: 189 PGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSG 248 PG I T+ +T E+++ L+ P++R+GQ ++A+ FLCS AS+V+ Q+++V+G Sbjct: 205 PGLIETEM----VTDEVKEHALKMIPLQRMGQVDEVASVVKFLCSDEASYVTRQVISVNG 260 Query: 249 GGV 251 G + Sbjct: 261 GLI 263 >4NBV-A nrPDB Length = 246 Score = 245 bits (627), Expect = 1e-65, Method: Composition-based stats. Identities = 86/245 (35%), Positives = 125/245 (51%), Gaps = 2/245 (0%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 ++L G+ AIITGA AGIG A FA GA VV+ D+ + G A R Sbjct: 1 MKLQGRVAIITGAAAGIGFATAQRFAEDGAIVVLCDVQEARVREAAARLAATGATVSAYR 60 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPK-PFDMPMADFRRAYELNVFSFFHL 125 D+T E+ A+ ++ +VDILVNNAG M A F ++N+ F+ Sbjct: 61 VDVTRRDEVDAMVAAVLAAHQRVDILVNNAGITKDARLAKMTEAQFDAVIDVNLKGVFNC 120 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 +Q VA M + G GVIL +S+ N T+YA+SK + A +LG K +RVN Sbjct: 121 AQAVAGLMTEQGKGVILNASSVVGLYGNFGQTNYAASKFGVIGFTKTWARELGPKGVRVN 180 Query: 186 GIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILT 245 + PG + T+ L++V ++ M +RRL +P +IA+ FL S AS+V+G + Sbjct: 181 AVCPGFVNTEILQTV-PDKVLDGMTSSCWLRRLAEPAEIASIYAFLASDDASYVNGVAIE 239 Query: 246 VSGGG 250 SGG Sbjct: 240 ASGGM 244 >2NM0-A nrPDB Length = 253 Score = 244 bits (624), Expect = 2e-65, Method: Composition-based stats. Identities = 68/239 (28%), Positives = 112/239 (46%), Gaps = 13/239 (5%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITS 71 + ++TG GIG IA FA AG V ++ + + A +CDIT Sbjct: 22 RSVLVTGGNRGIGLAIARAFADAGDKVAITYRSGEPPEG-----------FLAVKCDITD 70 Query: 72 EQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQLVA 130 +++ G V++L+ NAG + M DF E N+ F + + Sbjct: 71 TEQVEQAYKEIEETHGPVEVLIANAGVTKDQLLMRMSEEDFTSVVETNLTGTFRVVKRAN 130 Query: 131 PEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPG 190 M + G ++ I+S+ + +YA+SKA R++A +LG +NI N +APG Sbjct: 131 RAMLRAKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARSLARELGSRNITFNVVAPG 190 Query: 191 AILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 + TD K V+T E ++ P+ R +P++IA FL S AS+++G ++ V GG Sbjct: 191 FVDTDMTK-VLTDEQRANIVSQVPLGRYARPEEIAATVRFLASDDASYITGAVIPVDGG 248 >5U9P-A nrPDB Length = 265 Score = 244 bits (624), Expect = 2e-65, Method: Composition-based stats. Identities = 84/252 (33%), Positives = 130/252 (51%), Gaps = 2/252 (0%) Query: 5 DNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFA 64 D RLDG+ A+ITG+G GIG +A A AGA++V++D N + A + + G A Sbjct: 14 DRFRLDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARRFRDEGFAADH 73 Query: 65 CRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFF 123 D+ ++ A D +++G +DILVNNAG P D D+ +N+ F Sbjct: 74 AVFDVAEHAQVRAAIDEFEARVGAIDILVNNAGIQRRAPLDAFEPDDWHALMRVNLDGVF 133 Query: 124 HLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIR 183 +++Q VA M G G I+ I S+ +E + YA++K A L + M D I+ Sbjct: 134 NVAQAVARHMIARGHGKIINICSVQSELARPTIAPYAATKGAVRMLTKGMCADWARYGIQ 193 Query: 184 VNGIAPGAILTDALKSVITPEIEQKML-QHTPIRRLGQPQDIANAALFLCSPAASWVSGQ 242 NG+APG T+ ++++ L + TP R GQ ++ AA+FL S A+ +V+GQ Sbjct: 194 ANGLAPGYFETELNRALVDDAAFSDWLCKRTPAGRWGQVDELCGAAIFLASAASDFVNGQ 253 Query: 243 ILTVSGGGVQEL 254 L V GG + Sbjct: 254 TLFVDGGLTSAV 265 >2PH3-A nrPDB Length = 245 Score = 244 bits (624), Expect = 3e-65, Method: Composition-based stats. Identities = 72/245 (29%), Positives = 113/245 (46%), Gaps = 4/245 (1%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR--CDI 69 + A+ITGA GIG+ IA+ A G ++ + V E + G ++ Sbjct: 2 RKALITGASRGIGRAIALRLAEDGFALAIHYGQNREKAEEVAEEARRRGSPLVAVLGANL 61 Query: 70 TSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQL 128 + +AL A LG +D LVNNAG M D+ E N+ + F ++ Sbjct: 62 LEAEAATALVHQAAEVLGGLDTLVNNAGITRDTLLVRMKDEDWEAVLEANLSAVFRTTRE 121 Query: 129 VAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIA 188 M K G I+ ITS+ N +Y +SKA R +A + ++ I VN +A Sbjct: 122 AVKLMMKARFGRIVNITSVVGILGNPGQANYVASKAGLIGFTRAVAKEYAQRGITVNAVA 181 Query: 189 PGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSG 248 PG I T+ + + E+++ L+ P R G+P+++A A FL S A +++GQ L V G Sbjct: 182 PGFIETEMTERL-PQEVKEAYLKQIPAGRFGRPEEVAEAVAFLVSEKAGYITGQTLCVDG 240 Query: 249 GGVQE 253 G Sbjct: 241 GLTPH 245 >2AE2-A nrPDB Length = 260 Score = 244 bits (623), Expect = 3e-65, Method: Composition-based stats. Identities = 82/253 (32%), Positives = 134/253 (52%), Gaps = 6/253 (2%) Query: 6 NLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFAC 65 L+G A++TG GIG I A+ GASV N N + + + G + A Sbjct: 4 RWNLEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKVEAS 63 Query: 66 RCDITSEQELSALADFAISKL-GKVDILVNNAGGG-GPKPFDMPMADFRRAYELNVFSFF 123 CD++S E L + + GK++ILVNNAG + D + D+ +N + + Sbjct: 64 VCDLSSRSERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINFEAAY 123 Query: 124 HLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIR 183 HLS L P ++ + G ++ I+S++ Y ++K A L R +AF+ + NIR Sbjct: 124 HLSVLAHPFLKASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAFEWAKDNIR 183 Query: 184 VNGIAPGAILTDALK-SVITPEIEQ---KMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 VNG+ PG I T ++ ++ PE ++ K++ +RR+G+P+++A FLC PAAS+V Sbjct: 184 VNGVGPGVIATSLVEMTIQDPEQKENLNKLIDRCALRRMGEPKELAAMVAFLCFPAASYV 243 Query: 240 SGQILTVSGGGVQ 252 +GQI+ V GG + Sbjct: 244 TGQIIYVDGGLMA 256 >3VZS-A nrPDB Length = 257 Score = 242 bits (618), Expect = 1e-64, Method: Composition-based stats. Identities = 67/240 (27%), Positives = 120/240 (50%), Gaps = 3/240 (1%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVV-SDINADAANHVVDEIQQLGGQAFACRCDIT 70 + A +TG GIG I A G VV N+ +++ + LG A ++ Sbjct: 15 RIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGNVA 74 Query: 71 SEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFHLSQLV 129 D S++G+VD+L+NNAG F M AD+ + N+ S F++++ V Sbjct: 75 DWDSTKTAFDKVKSEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNVTKQV 134 Query: 130 APEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAP 189 M G G I+ I+S+ + T+Y+++KA +A ++ K + VN ++P Sbjct: 135 IDGMADRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNTVSP 194 Query: 190 GAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 G I TD +K+ I ++ K++ P++RLG P++IA+ +L S + + +G +++GG Sbjct: 195 GYIATDMVKA-IRQDVLDKIVATIPVKRLGLPEEIASICAWLSSEESGFSTGADFSLNGG 253 >6CI9-A nrPDB Length = 259 Score = 242 bits (618), Expect = 1e-64, Method: Composition-based stats. Identities = 77/246 (31%), Positives = 121/246 (49%), Gaps = 3/246 (1%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 L+G+ AI+TG GIG+ IA TFA AG VV++ N D + V ++ G+ A R Sbjct: 6 SLEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVRA 65 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGG-PKPFDMPMADFRRAYELNVFSFFHLS 126 D+T ++ +S+ G +DI+ NAG + D+ D + +N ++ Sbjct: 66 DVTDPEDARRTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKGTVYIV 125 Query: 127 QLVAPEMEKNGGGVILTITSMAA-ENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 Q + +G G ++ +S+ + Y +SKAA +R A +L K I +N Sbjct: 126 QAALQALTASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAMELAPKKITIN 185 Query: 186 GIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILT 245 + PG I+T+ L + + +M P RLG DI NAALF + A++V+GQ L Sbjct: 186 AVLPGNIMTEGLDE-MGQDYLDQMASAIPAGRLGSVADIGNAALFFATDEAAYVTGQTLV 244 Query: 246 VSGGGV 251 V GG V Sbjct: 245 VDGGQV 250 >3OEC-A nrPDB Length = 317 Score = 242 bits (617), Expect = 1e-64, Method: Composition-based stats. Identities = 74/275 (26%), Positives = 125/275 (45%), Gaps = 30/275 (10%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDI------------NADAANHVVDEI 55 RL GK A ITGA G G+ A+ A GA +V D+ + + V + Sbjct: 43 RLQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKETVRLV 102 Query: 56 QQLGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGG-GPKPFDMPMADFRRA 114 ++ G + A + D+ L A+ D A+++ G +DILV+N G + + + Sbjct: 103 EEQGRRIIARQADVRDLASLQAVVDEALAEFGHIDILVSNVGISNQGEVVSLTDQQWSDI 162 Query: 115 YELNVFSFFHLSQLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNM 173 + N+ +H + V P M + G GG ++ ++S + YA+SK L+ ++ Sbjct: 163 LQTNLIGAWHACRAVLPSMIERGQGGSVIFVSSTVGLRGAPGQSHYAASKHGVQGLMLSL 222 Query: 174 AFDLGEKNIRVNGIAPGAILTDA-----LKSVITPEIEQ----------KMLQHTPIRRL 218 A ++G NIRVN + PGA+ T+ L + P +E L PI Sbjct: 223 ANEVGRHNIRVNSVNPGAVNTEMALNEKLLKMFLPHLENPTREDAAELFSQLTLLPIP-W 281 Query: 219 GQPQDIANAALFLCSPAASWVSGQILTVSGGGVQE 253 +P+D++NA +L S A ++ G + V GG + Sbjct: 282 VEPEDVSNAVAWLASDEARYIHGAAIPVDGGQLAR 316 >3OIC-A nrPDB Length = 258 Score = 239 bits (610), Expect = 9e-64, Method: Composition-based stats. Identities = 77/243 (31%), Positives = 126/243 (51%), Gaps = 3/243 (1%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGASVVVSD-INADAANHVVDEIQQLGGQAFACRCD 68 KCA++TG+ G+GK AI A G ++V++ + AA +EI++LG + + + Sbjct: 3 QNKCALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALETAEEIEKLGVKVLVVKAN 62 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQ 127 + ++ + G++D+ VNNA G +P ++ + +N + +Q Sbjct: 63 VGQPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELEETHWDWTMNINAKALLFCAQ 122 Query: 128 LVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGI 187 A MEKNGGG I++I+S+ + N T+ SKAA L R +A +L K I VN + Sbjct: 123 EAAKLMEKNGGGHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAVELSPKQIIVNAV 182 Query: 188 APGAILTDALKSVITPE-IEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTV 246 + GAI TDALK E + + Q+TP R+ + +D+ + FL S A + GQ + V Sbjct: 183 SGGAIDTDALKHFPNREDLLEDARQNTPAGRMVEIKDMVDTVEFLVSSKADMIRGQTIIV 242 Query: 247 SGG 249 GG Sbjct: 243 DGG 245 >5OJG-A nrPDB Length = 260 Score = 238 bits (609), Expect = 1e-63, Method: Composition-based stats. Identities = 82/260 (31%), Positives = 128/260 (49%), Gaps = 7/260 (2%) Query: 2 FNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG- 60 S+ R +GK AI+T A GIG IA GASVV+ N + ++ ++ G Sbjct: 1 MPSNCRRFEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLT 60 Query: 61 QAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGG--PKPFDMPMADFRRAYELN 118 + I S + L DF + K GK++ILVNN G ++ + + +E+N Sbjct: 61 KVAGIAGHIASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVN 120 Query: 119 VFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLG 178 V + F +++LV P + K GGG I+ S +A + +Y +K L R +A L Sbjct: 121 VKAGFQMTKLVHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLA 180 Query: 179 EKNIRVNGIAPGAILTDALKSVI----TPEIEQKMLQHTPIRRLGQPQDIANAALFLCSP 234 + NIRVNGIAPG I T + + E E +Q + RLG P D A +L S Sbjct: 181 KDNIRVNGIAPGVIKTKMSQVLWDGGEDAEKELTDIQEIALGRLGVPDDCAGTVAYLASD 240 Query: 235 AASWVSGQILTVSGGGVQEL 254 +S+++G+++ ++GG L Sbjct: 241 DSSYITGEMIIIAGGVQARL 260 >5VT6-A nrPDB Length = 269 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 66/243 (27%), Positives = 115/243 (47%), Gaps = 2/243 (0%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGASVVVSDI-NADAANHVVDEIQQLGGQAFACRCD 68 + A +TG G+G I+ AG +V VS D + + + G A D Sbjct: 24 AKRVAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWLMHERDAGRDFKAYAVD 83 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQ 127 + + A+ ++ GKVD+L+NNAG F M D+ ++ + F++++ Sbjct: 84 VADFESCERCAEKVLADFGKVDVLINNAGITRDATFMKMTKGDWDAVMRTDLDAMFNVTK 143 Query: 128 LVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGI 187 M + G I+ I S+ +YAS+KA + +A + ++ I VN + Sbjct: 144 QFIAGMVERRFGRIVNIGSVNGSRGAFGQANYASAKAGIHGFTKTLALETAKRGITVNTV 203 Query: 188 APGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVS 247 +PG + T +++V +E K+L P+ RLG+P ++A FLCS A +V+G L ++ Sbjct: 204 SPGYLATAMVEAVPQDVLEAKILPQIPVGRLGRPDEVAALIAFLCSDDAGFVTGADLAIN 263 Query: 248 GGG 250 GG Sbjct: 264 GGM 266 >1GEG-A nrPDB Length = 256 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 80/253 (31%), Positives = 117/253 (46%), Gaps = 12/253 (4%) Query: 11 GKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDIT 70 K A++TGAG GIGK IA+ G +V ++D N A V EI Q GG A A + D++ Sbjct: 2 KKVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDVS 61 Query: 71 SEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFHLSQLV 129 ++ A + A LG D++VNNAG P + + + Y +NV Q Sbjct: 62 DRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWGIQAA 121 Query: 130 APEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIA 188 +K G GG I+ S A N + Y+SSK A L + A DL I VNG Sbjct: 122 VEAFKKEGHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGITVNGYC 181 Query: 189 PGAILTDALKSVITPEIE----------QKMLQHTPIRRLGQPQDIANAALFLCSPAASW 238 PG + T + E + + + RL +P+D+A +L SP + + Sbjct: 182 PGIVKTPMWAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAACVSYLASPDSDY 241 Query: 239 VSGQILTVSGGGV 251 ++GQ L + GG V Sbjct: 242 MTGQSLLIDGGMV 254 >1YXM-A nrPDB Length = 303 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 67/250 (26%), Positives = 118/250 (47%), Gaps = 10/250 (4%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQ-----LGGQAF 63 L G+ AI+TG GIGK I G++VV++ + DE+Q + Sbjct: 16 LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVI 75 Query: 64 ACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSF 122 +C+I +E+E++ L + GK++ LVNN GG P + + + E N+ Sbjct: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135 Query: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182 F++ + V K GG I+ I + + +++A +L +++A + I Sbjct: 136 FYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194 Query: 183 RVNGIAPGAILTDAL---KSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 R+N +APG I + + Q P +R+G P+++++ FL SPAAS++ Sbjct: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254 Query: 240 SGQILTVSGG 249 +GQ + V GG Sbjct: 255 TGQSVDVDGG 264 >4Z9Y-A nrPDB Length = 253 Score = 237 bits (606), Expect = 3e-63, Method: Composition-based stats. Identities = 81/252 (32%), Positives = 132/252 (52%), Gaps = 5/252 (1%) Query: 5 DNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFA 64 ++ L GK A+ITG G+G+ +AI A AG +V +N ++++ LG + + Sbjct: 4 NSFDLQGKVALITGCDTGLGQGMAIGLAQAGCDIV--GVNIVEPKDTIEKVTALGRRFLS 61 Query: 65 CRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPK-PFDMPMADFRRAYELNVFSFF 123 D+++ + L + A+++ G VDILVNNAG + + ++ LN+ S F Sbjct: 62 LTADMSNVSGHAELVEKAVAEFGHVDILVNNAGIIRREDAIEFSEKNWDDVMNLNIKSVF 121 Query: 124 HLSQLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182 +SQ VA + K G GG I+ I SM + I + SY +SK+A + R MA + + I Sbjct: 122 FMSQTVARQFIKQGKGGKIINIASMLSFQGGIRVPSYTASKSAVMGVTRLMANEWAKHGI 181 Query: 183 RVNGIAPGAILTDALKSVITPEIEQK-MLQHTPIRRLGQPQDIANAALFLCSPAASWVSG 241 VN IAPG + T+ + + E K +L P R G PQD+ ++FL S A+ +++G Sbjct: 182 NVNAIAPGYMATNNTQQLRADEERSKEILDRIPAGRWGLPQDLMGPSVFLASSASDYING 241 Query: 242 QILTVSGGGVQE 253 + V GG + Sbjct: 242 YTIAVDGGWLAR 253 >4CQL-A nrPDB Length = 261 Score = 237 bits (605), Expect = 3e-63, Method: Composition-based stats. Identities = 71/252 (28%), Positives = 125/252 (49%), Gaps = 11/252 (4%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLG-------G 60 RL A++TGAG+GIG+ +++ A GA+V D++ AA V + G G Sbjct: 8 RLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRG 67 Query: 61 QAFACRCDITSEQELSALADFAISKLGKVD-ILVNNAGGGGPK-PFDMPMADFRRAYELN 118 A + D++ + L + + + ++V+ AG + M D+ + +N Sbjct: 68 NHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127 Query: 119 VFSFFHLSQLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDL 177 + F ++Q A + NG G I+ I+S+ + N+ T+YA+SKA L + A +L Sbjct: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAREL 187 Query: 178 GEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAAS 237 G IR N + PG I T + V ++ K+ + P+ LG P+D+A+ FL S + Sbjct: 188 GRHGIRCNSVLPGFIATPMTQKV-PQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSG 246 Query: 238 WVSGQILTVSGG 249 +++G + V+GG Sbjct: 247 YITGTSVEVTGG 258 >3R3S-A nrPDB Length = 294 Score = 237 bits (605), Expect = 3e-63, Method: Composition-based stats. Identities = 80/247 (32%), Positives = 133/247 (53%), Gaps = 7/247 (2%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADA--ANHVVDEIQQLGGQAFAC 65 RL + A++TG +GIG+ AI +A GA V ++ + A+ A V I++ G +A Sbjct: 46 RLKDRKALVTGGDSGIGRAAAIAYAREGADVAINYLPAEEEDAQQVKALIEECGRKAVLL 105 Query: 66 RCDITSEQELSALADFAISKLGKVDILVNNAGGGG--PKPFDMPMADFRRAYELNVFSFF 123 D++ E +L A LG +DIL AG P+ D+ F++ + +NVF+ F Sbjct: 106 PGDLSDESFARSLVHKAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQTFAVNVFALF 165 Query: 124 HLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIR 183 ++Q P + K G I+T +S+ A + ++ YA++KAA + R +A + EK IR Sbjct: 166 WITQEAIPLLPK--GASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIR 223 Query: 184 VNGIAPGAILTDA-LKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQ 242 VN +APG I T + T + + Q TP++R GQP ++A ++L S +S+V+ + Sbjct: 224 VNIVAPGPIWTALQISGGQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQESSYVTAE 283 Query: 243 ILTVSGG 249 + V GG Sbjct: 284 VHGVCGG 290 >2Q2Q-A nrPDB Length = 255 Score = 237 bits (605), Expect = 4e-63, Method: Composition-based stats. Identities = 73/256 (28%), Positives = 116/256 (45%), Gaps = 13/256 (5%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 L GK A++TG+ +GIG IA A AGA++V++ A + EI + G +A D Sbjct: 2 LKGKTALVTGSTSGIGLGIAQVLARAGANIVLNGFGDPAP--ALAEIARHGVKAVHHPAD 59 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFHLSQ 127 ++ ++ AL A + G VDILVNNAG P + P+ + + LN+ + FH ++ Sbjct: 60 LSDVAQIEALFALAEREFGGVDILVNNAGIQHVAPVEQFPLESWDKIIALNLSAVFHGTR 119 Query: 128 LVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGI 187 L P M G I+ I S+ + +Y ++K L + + + N+ N I Sbjct: 120 LALPGMRARNWGRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGLETATSNVTCNAI 179 Query: 188 APGAILTDALKSVITPEIEQK----------MLQHTPIRRLGQPQDIANAALFLCSPAAS 237 PG +LT ++ I + + P P+ + LFLCS A S Sbjct: 180 CPGWVLTPLVQKQIDDRAANGGDPLQAQHDLLAEKQPSLAFVTPEHLGELVLFLCSEAGS 239 Query: 238 WVSGQILTVSGGGVQE 253 V G V GG + + Sbjct: 240 QVRGAAWNVDGGWLAQ 255 >5T5Q-A nrPDB Length = 247 Score = 237 bits (604), Expect = 5e-63, Method: Composition-based stats. Identities = 77/247 (31%), Positives = 135/247 (54%), Gaps = 6/247 (2%) Query: 4 SDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAF 63 S + + ++TGA GIG+ IA F +GA++V++D++ + + + A Sbjct: 2 SMKFEFENRTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSPERIAT 61 Query: 64 ACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSF 122 + D +S + A+ + G +D LV +AG KPF +M AD+ R +N+ Sbjct: 62 -IKADASSADDAEKTVALAMERFGGIDFLVPSAGIYQAKPFAEMSDADWHRTISINLDGV 120 Query: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182 F+L + P ++++ I+T+ S+AA Y ++K A + R ++ +L K Sbjct: 121 FYLCKRALPALKED--SSIVTLASLAAYRGAYVNAHYGATKGAMVSMTRALSRELAPKT- 177 Query: 183 RVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQ 242 RVNG++PG I T ++ +++ M Q TP++RLG+P +IA+ FLCSPAAS+V+G+ Sbjct: 178 RVNGVSPGIIETPMTSELLKTRMDETMTQ-TPLKRLGKPSEIASVIAFLCSPAASFVTGE 236 Query: 243 ILTVSGG 249 + V+GG Sbjct: 237 TIQVNGG 243 >5YSS-A nrPDB Length = 256 Score = 234 bits (598), Expect = 2e-62, Method: Composition-based stats. Identities = 72/258 (27%), Positives = 123/258 (47%), Gaps = 13/258 (5%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 + L GK A++TG+ +GIG IA A AGA+++++ + D + Q G Sbjct: 1 MNLTGKTALVTGSTSGIGLGIAQVLAQAGATLILNGFGD--VDAAKDAVAQYGKTPGYHG 58 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDM-PMADFRRAYELNVFSFFHL 125 D++ E +++ + +A S+ G VDIL+NNAG P + P+ + +N+ S FH Sbjct: 59 ADLSDEAQIADMMRYAESEFGGVDILINNAGIQHVSPIETFPVDKWNAIIAINLSSVFHT 118 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 ++L P M G I+ I S+ + ++Y ++K L + +A + + I N Sbjct: 119 TRLALPGMRARNWGRIINIASVHGLVASKEKSAYVAAKHGVVGLTKTIALETAQTEITCN 178 Query: 186 GIAPGAILTDALKSVITPEIEQK----------MLQHTPIRRLGQPQDIANAALFLCSPA 235 + PG +LT ++ I I + + + P R P+ + N ALFLCS Sbjct: 179 ALCPGWVLTPLVQQQIDKRIAEGAEPEAARDALLAEKQPSREFVTPEQLGNLALFLCSDG 238 Query: 236 ASWVSGQILTVSGGGVQE 253 A+ V G + GG V + Sbjct: 239 AAQVRGVAWNMDGGWVAQ 256 >5OVL-A nrPDB Length = 300 Score = 233 bits (594), Expect = 6e-62, Method: Composition-based stats. Identities = 62/240 (25%), Positives = 108/240 (45%), Gaps = 13/240 (5%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITS 71 + ++TG GIG IA A G V V+ + A + + F +CD+T Sbjct: 69 RSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDL-----------FGVQCDVTD 117 Query: 72 EQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQLVA 130 + G V++LV NAG M F N+ F +Q + Sbjct: 118 SAAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRAS 177 Query: 131 PEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPG 190 M++ G I+ I S++ N +YA++KA + R+++ +L + + N +APG Sbjct: 178 RTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPG 237 Query: 191 AILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGGG 250 I T+ +++ I+ L P +R+G +++A A FL S AS+++G ++ V GG Sbjct: 238 YIDTEMTRAL-DERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVIPVDGGM 296 >4IIV-A nrPDB Length = 267 Score = 232 bits (593), Expect = 9e-62, Method: Composition-based stats. Identities = 65/253 (25%), Positives = 128/253 (50%), Gaps = 8/253 (3%) Query: 2 FNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSD-INADAANHVVDEIQQLGG 60 F S+ + + ++TGA GIG+ IA A G ++ V +A A ++ I GG Sbjct: 20 FQSNAMS---RSVLVTGASKGIGRAIARQLAADGFNIGVHYHRDAAGAQETLNAIVANGG 76 Query: 61 QAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNV 119 D+ + ++ + + I++ G +V+NAG F + D+ N+ Sbjct: 77 NGRLLSFDVANREQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPALSNDDWDAVIHTNL 136 Query: 120 FSFFHLSQLV-APEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLG 178 SF+++ Q P + GG I+T++S++ N +Y+++KA + +A +L Sbjct: 137 DSFYNVIQPCIMPMIGARQGGRIITLSSVSGVMGNRGQVNYSAAKAGIIGATKALAIELA 196 Query: 179 EKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASW 238 ++ I VN IAPG I T ++ + ++ + P++R+GQ +++A A +L S A + Sbjct: 197 KRKITVNCIAPGLIDTGMIE--MEESALKEAMSMIPMKRMGQAEEVAGLASYLMSDIAGY 254 Query: 239 VSGQILTVSGGGV 251 V+ Q+++++GG + Sbjct: 255 VTRQVISINGGML 267 >3V2G-A nrPDB Length = 271 Score = 230 bits (588), Expect = 3e-61, Method: Composition-based stats. Identities = 85/254 (33%), Positives = 127/254 (50%), Gaps = 9/254 (3%) Query: 2 FNSD--NLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINA-DAANHVVDEIQQL 58 F S ++ L GK A +TG GIG IA A GA+V ++ +NA + A VV EI+Q Sbjct: 20 FQSMMTSISLAGKTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQA 79 Query: 59 GGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYEL 117 GG+A A R D + + + LG +DILVN+AG P + +ADF + Sbjct: 80 GGRAVAIRADNRDAEAIEQAIRETVEALGGLDILVNSAGIWHSAPLEETTVADFDEVMAV 139 Query: 118 NVFSFFHLSQLVAPEMEKNGGGVILTITSMAAE-NKNINMTSYASSKAAASHLVRNMAFD 176 N + F + + + GG I+TI S AE ++ Y++SKAA + L + +A D Sbjct: 140 NFRAPFVAIRSASRHL--GDGGRIITIGSNLAELVPWPGISLYSASKAALAGLTKGLARD 197 Query: 177 LGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAA 236 LG + I VN + PG+ TD + + + + G+PQDIA +L P Sbjct: 198 LGPRGITVNIVHPGSTDTDM--NPADGDHAEAQRERIATGSYGEPQDIAGLVAWLAGPQG 255 Query: 237 SWVSGQILTVSGGG 250 +V+G LT+ GG Sbjct: 256 KFVTGASLTIDGGA 269 >4KMS-A nrPDB Length = 249 Score = 230 bits (588), Expect = 3e-61, Method: Composition-based stats. Identities = 71/239 (29%), Positives = 119/239 (49%), Gaps = 7/239 (2%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSE 72 AI+TG GIGK A+ G +VV + + E+++ G C ++ Sbjct: 12 IAIVTGGTRGIGKATALELKNKGLTVVANFFSN---YDAAKEMEEKYGIKTKCW-NVADF 67 Query: 73 QELSALADFAISKLGK-VDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFHLSQLVA 130 +E + K V ILVNNAG K M D+ +N+ S F++S V Sbjct: 68 EECRQAVKEIEEEFKKPVSILVNNAGITKDKMLHRMSHQDWNDVINVNLNSCFNMSSSVM 127 Query: 131 PEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPG 190 +M G I+ I+S+ A+ + T+Y+++KA + +A + KNI VN IAPG Sbjct: 128 EQMRNQDYGRIVNISSINAQAGQVGQTNYSAAKAGIIGFTKALARETASKNITVNCIAPG 187 Query: 191 AILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 I T+ + + ++ K++ P +RLGQP++IA A FL A +++G+ ++++GG Sbjct: 188 YIATEMV-GAVPEDVLAKIINSIPKKRLGQPEEIARAVAFLVDENAGFITGETISINGG 245 >4RZI-B nrPDB Length = 240 Score = 230 bits (586), Expect = 6e-61, Method: Composition-based stats. Identities = 72/245 (29%), Positives = 124/245 (50%), Gaps = 13/245 (5%) Query: 6 NLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFAC 65 +L L+ K ++TG GIG I GA V +D+ D N +A Sbjct: 3 SLGLEDKVIVVTGGNRGIGAAIVKLLQEMGAKVAFTDLATDGGNT----------EALGV 52 Query: 66 RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFH 124 ++T + ++A A KLG V +V NAG F + AD+ +N+ + Sbjct: 53 VANVTDLESMTAAAAEITDKLGPVYGVVANAGITKDNFFPKLTPADWDAVLNVNLKGVAY 112 Query: 125 LSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 + M + G I+ I+S++ E N+ T+Y+++KA +++++A + +R Sbjct: 113 SIKPFIEGMYERKAGSIVAISSISGERGNVGQTNYSATKAGVIGMMKSLAREGARYGVRA 172 Query: 185 NGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSP-AASWVSGQI 243 N +APG I T+ + I +I +K+ + P RR G+P++IA A FL SP A+S+V+G++ Sbjct: 173 NAVAPGFIDTEMTLA-IREDIREKITKEIPFRRFGKPEEIAWAVAFLLSPVASSYVTGEV 231 Query: 244 LTVSG 248 L V+G Sbjct: 232 LRVNG 236 >4IS3-A nrPDB Length = 268 Score = 230 bits (586), Expect = 7e-61, Method: Composition-based stats. Identities = 72/250 (28%), Positives = 121/250 (48%), Gaps = 5/250 (2%) Query: 2 FNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG- 60 F NL + K IITG GIG A F GA V + + + + ++++L Sbjct: 17 FQGMNL-VQDKVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYPE 75 Query: 61 -QAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELN 118 + D+TS + A K G++D+++NNAG F + +F+ ++N Sbjct: 76 EEVLGFAPDLTSRDAVMAAVGQVAQKYGRLDVMINNAGITSNNVFSRVSEEEFKHIMDIN 135 Query: 119 VFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLG 178 V F+ + M+ GVI+ S+ +++ Y +SKA+ L + ++ Sbjct: 136 VTGVFNGAWCAYQCMKDAKKGVIINTASVTGIFGSLSGVGYPASKASVIGLTHGLGREII 195 Query: 179 EKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASW 238 KNIRV G+APG + TD PEI + L+ P++R+ +P++IAN LFL S AS Sbjct: 196 RKNIRVVGVAPGVVNTDMTNG-NPPEIMEGYLKALPMKRMLEPEEIANVYLFLASDLASG 254 Query: 239 VSGQILTVSG 248 ++ ++V G Sbjct: 255 ITATTVSVDG 264 >3V2H-A nrPDB Length = 281 Score = 229 bits (584), Expect = 1e-60, Method: Composition-based stats. Identities = 75/267 (28%), Positives = 127/267 (47%), Gaps = 17/267 (6%) Query: 1 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINA-DAANHVVDEIQQLG 59 ++ + K A+ITG+ +GIG IA T A AGA++V++ A D V DE+ L Sbjct: 18 LYFQSMMT---KTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAGLS 74 Query: 60 -GQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGP-KPFDMPMADFRRAYEL 117 G D+T E++ + + G DILVNNAG K D P+ + R + Sbjct: 75 SGTVLHHPADMTKPSEIADMMAMVADRFGGADILVNNAGVQFVEKIEDFPVEQWDRIIAV 134 Query: 118 NVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDL 177 N+ S FH + P M+K G G I+ I S + ++Y ++K L + +A ++ Sbjct: 135 NLSSSFHTIRGAIPPMKKKGWGRIINIASAHGLVASPFKSAYVAAKHGIMGLTKTVALEV 194 Query: 178 GEKNIRVNGIAPGAILTDALKSVITPEIE-----------QKMLQHTPIRRLGQPQDIAN 226 E + VN I PG +LT ++ I + + ML+ P ++ + +A+ Sbjct: 195 AESGVTVNSICPGYVLTPLVEKQIPDQARTRGITEEQVINEVMLKGQPTKKFITVEQVAS 254 Query: 227 AALFLCSPAASWVSGQILTVSGGGVQE 253 AL+L A+ ++G +++ GG + Sbjct: 255 LALYLAGDDAAQITGTHVSMDGGWTAQ 281 >4MOW-A nrPDB Length = 256 Score = 229 bits (584), Expect = 1e-60, Method: Composition-based stats. Identities = 89/246 (36%), Positives = 137/246 (55%), Gaps = 6/246 (2%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADA-ANHVVDEIQQLGGQAFACR 66 +L GK AI+TGA GIG IA A GA+VVV+ ++ A A+ VV I + GG+A A Sbjct: 11 KLAGKVAIVTGASKGIGAAIAKALADEGAAVVVNYASSKAGADAVVSAITEAGGRAVAVG 70 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFHL 125 D++ + + D AI G++D+LVNN+G P + + +RR ++ NVF Sbjct: 71 GDVSKAADAQRIVDTAIETYGRLDVLVNNSGVYEFAPIEAITEEHYRRQFDTNVFGVLLT 130 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 +Q + + G I+ I+S+ Y+ +K A + +A +LG + IRVN Sbjct: 131 TQAAVKHLGE--GASIINISSVVTSITPPASAVYSGTKGAVDAITGVLALELGPRKIRVN 188 Query: 186 GIAPGAILTDALK--SVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQI 243 I PG I+T+ +I ++E ++L TP+ RLG+P DIA+ A+FL S A W++G+ Sbjct: 189 AINPGMIVTEGTHSAGIIGSDLEAQVLGQTPLGRLGEPNDIASVAVFLASDDARWMTGEH 248 Query: 244 LTVSGG 249 L VSGG Sbjct: 249 LVVSGG 254 >1NFF-A nrPDB Length = 260 Score = 229 bits (584), Expect = 1e-60, Method: Composition-based stats. Identities = 68/248 (27%), Positives = 111/248 (44%), Gaps = 10/248 (4%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 RL GK A+++G G+G GA VV DI + + +L A Sbjct: 4 RLTGKVALVSGGARGMGASHVRAMVAEGAKVVFGDILDEEGKAMA---AELADAARYVHL 60 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLS 126 D+T + A D A++ G + +LVNNAG D + +++R ++N+ F Sbjct: 61 DVTQPAQWKAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLTGVFLGI 120 Query: 127 QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNG 186 + V M++ G G I+ I+S+ + Y ++K A L ++ A +LG IRVN Sbjct: 121 RAVVKPMKEAGRGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTALELGPSGIRVNS 180 Query: 187 IAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTV 246 I PG + T V T + R +P +++N ++L S +S+ +G V Sbjct: 181 IHPGLVKTPMTDWVPEDIF------QTALGRAAEPVEVSNLVVYLASDESSYSTGAEFVV 234 Query: 247 SGGGVQEL 254 GG V L Sbjct: 235 DGGTVAGL 242 >4DBZ-A nrPDB Length = 281 Score = 228 bits (583), Expect = 1e-60, Method: Composition-based stats. Identities = 72/250 (28%), Positives = 112/250 (44%), Gaps = 13/250 (5%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSE 72 A++TGA +GIG EIA G V V + + E+++ G +A CD+ S Sbjct: 28 VALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGVEADGRTCDVRSV 87 Query: 73 QELSALADFAISKLGKVDILVNNAGG-GGPKPFDMPMADFRRAYELNVFSFFHLSQLVAP 131 E+ AL + + G VD+LVNNAG GG ++ + E N+ F +++ V Sbjct: 88 PEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELADELWLDVVETNLTGVFRVTKQVLK 147 Query: 132 E--MEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAP 189 M + G G I+ I S + ++ Y++SK + + +L I VN + P Sbjct: 148 AGGMLERGTGRIVNIASTGGKQGLVHAAPYSASKHGVVGFTKALGLELARTGITVNAVCP 207 Query: 190 GAILTDALKS----------VITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 G + T S V T E ++ PI R QP ++A +L P A+ V Sbjct: 208 GFVETPMAASVREHYSDIWEVSTEEAFDRITARVPIGRYVQPSEVAEMVAYLIGPGAAAV 267 Query: 240 SGQILTVSGG 249 + Q L V GG Sbjct: 268 TAQALNVCGG 277 >3WTC-A nrPDB Length = 262 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 75/260 (28%), Positives = 123/260 (47%), Gaps = 12/260 (4%) Query: 4 SDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAF 63 ++ L GK A +TGA GIGK IA+ A GA V++ D+ D E++ LG +A Sbjct: 1 GSHMSLSGKIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEALGRRAV 60 Query: 64 ACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKP-FDMPMADFRRAYELNVFSF 122 A DI++ + + A LG +DI+VNNAG KP D+ A+ + + +NV Sbjct: 61 ALTADISNRDQFRSTLADAAKTLGGLDIMVNNAGICQVKPILDIEPAEIEKIFSINVQGV 120 Query: 123 FHLSQLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKN 181 Q A ++ G G I+ S+A + +Y+++K A L ++ A +L Sbjct: 121 LWGMQAAATLFKEKGTKGKIINACSIAGHEGYPLLGAYSATKFAVRALTQSAAKELASSG 180 Query: 182 IRVNGIAPGAILTDALKSVITPEIE----------QKMLQHTPIRRLGQPQDIANAALFL 231 I VN PG + TD ++ E +K ++ + R+ D+A +L Sbjct: 181 ITVNSYCPGIVGTDMWVTIDKRMAEITGTEIGATYKKYVEGIALGRVETADDVAGFVAYL 240 Query: 232 CSPAASWVSGQILTVSGGGV 251 S A +++GQ + + GG V Sbjct: 241 SSSDADYMTGQSVLIDGGLV 260 >5OVJ-A nrPDB Length = 256 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 62/240 (25%), Positives = 108/240 (45%), Gaps = 13/240 (5%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITS 71 + ++TG GIG IA A G V V+ + A + + F +CD+T Sbjct: 25 RSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDL-----------FGVQCDVTD 73 Query: 72 EQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQLVA 130 + G V++LV NAG M F N+ F +Q + Sbjct: 74 SAAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRAS 133 Query: 131 PEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPG 190 M++ G I+ I S++ N +YA++KA + R+++ +L + + N +APG Sbjct: 134 RTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPG 193 Query: 191 AILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGGG 250 I T+ +++ I+ L P +R+G +++A A FL S AS+++G ++ V GG Sbjct: 194 YIDTEMTRAL-DERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVIPVDGGM 252 >3WYE-A nrPDB Length = 256 Score = 227 bits (579), Expect = 4e-60, Method: Composition-based stats. Identities = 83/253 (32%), Positives = 125/253 (49%), Gaps = 12/253 (4%) Query: 11 GKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDIT 70 K A++TGAG GIGK IA+ G +V ++D N A V EI Q GG A A + D++ Sbjct: 2 KKVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDVS 61 Query: 71 SEQELSALADFAISKLGKVDILVNNAGGGGPKP-FDMPMADFRRAYELNVFSFFHLSQLV 129 ++ A + A LG D++VNNAG KP ++ D ++ Y +NVFS F Q Sbjct: 62 DRDQVFAAVEQARKTLGGFDVIVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQAA 121 Query: 130 APEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIA 188 +K G GG I+ S+AA +++Y+++K A L + A DL I VNG Sbjct: 122 VEAFKKEGHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAARDLAPLGITVNGYC 181 Query: 189 PGAILTDALKSVITP----------EIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASW 238 PG + T + + E ++ + R P+D+A FL SP + + Sbjct: 182 PGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLASPDSDY 241 Query: 239 VSGQILTVSGGGV 251 ++GQ L + GG V Sbjct: 242 MTGQSLLIDGGMV 254 >2P91-A nrPDB Length = 285 Score = 226 bits (578), Expect = 5e-60, Method: Composition-based stats. Identities = 64/249 (25%), Positives = 117/249 (46%), Gaps = 10/249 (4%) Query: 9 LDGKCAIITGAG--AGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 L+GK A+ITG I IA +F GA + + V EI + G + Sbjct: 19 LEGKRALITGVANERSIAYGIAKSFHREGAQLAFTYATPK-LEKRVREIAKGFGSDLVVK 77 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-----DMPMADFRRAYELNVFS 121 CD++ ++++ L F G +DI+V++ + F D F+ A +++V+S Sbjct: 78 CDVSLDEDIKNLKKFLEENWGSLDIIVHSIAYAPKEEFKGGVIDTSREGFKIAMDISVYS 137 Query: 122 FFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKN 181 L++ + P M + G I+T++ AE + +KAA VR +A+D+ + Sbjct: 138 LIALTRELLPLM-EGRNGAIVTLSYYGAEKVVPHYNVMGIAKAALESTVRYLAYDIAKHG 196 Query: 182 IRVNGIAPGAILTDALKSVITPEIE-QKMLQHTPIRRLGQPQDIANAALFLCSPAASWVS 240 R+N I+ G + T A S+ + + + P + +D+ + A+FLCS A ++ Sbjct: 197 HRINAISAGPVKTLAAYSITGFHLLMEHTTKVNPFGKPITIEDVGDTAVFLCSDWARAIT 256 Query: 241 GQILTVSGG 249 G+++ V G Sbjct: 257 GEVVHVDNG 265 >3W8F-A nrPDB Length = 260 Score = 226 bits (577), Expect = 6e-60, Method: Composition-based stats. Identities = 72/259 (27%), Positives = 115/259 (44%), Gaps = 14/259 (5%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN--ADAANHVVDEIQQLGGQAFACR 66 L GK A++TG+ +GIG +A A AGA VV++ D + G +A+ Sbjct: 2 LKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVKAYYLN 61 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFHL 125 D++ Q A LG +DILVNNAG P + P+ + LN+ + FH Sbjct: 62 ADLSDAQATRDFIAKAAEALGGLDILVNNAGIQHTAPIEEFPVDKWNAIIALNLSAVFHG 121 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 + P M+K G G I+ I S ++N ++Y ++K L + A + K I N Sbjct: 122 TAAALPIMQKQGWGRIINIASAHGLVASVNKSAYVAAKHGVVGLTKVTALENAGKGITCN 181 Query: 186 GIAPGAILTDALKSV-----------ITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSP 234 I PG + T ++ I + + + P + P+ + AA+FL S Sbjct: 182 AICPGWVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQPSLQFVTPEQLGGAAVFLSSA 241 Query: 235 AASWVSGQILTVSGGGVQE 253 AA ++G L++ GG Sbjct: 242 AADQMTGTTLSLDGGWTAR 260 >3UVE-A nrPDB Length = 286 Score = 226 bits (577), Expect = 7e-60, Method: Composition-based stats. Identities = 70/281 (24%), Positives = 115/281 (40%), Gaps = 35/281 (12%) Query: 4 SDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN----------------ADA 47 S R++GK A +TGA G G+ A+ A GA ++ DI + Sbjct: 4 SMTGRVEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPED 63 Query: 48 ANHVVDEIQQLGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGG--GPKPFD 105 D ++ + D+ L A D + +LG++DI+V NAG G G Sbjct: 64 LAETADLVKGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNGGDTLDK 123 Query: 106 MPMADFRRAYELNVFSFFHLSQLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKA 164 D+ ++N+ + + P M G GG I+ +S+ + Y ++K Sbjct: 124 TSEEDWTEMIDINLAGVWKTVKAGVPHMIAGGRGGSIILTSSVGGLKAYPHTGHYVAAKH 183 Query: 165 AASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKS-----VITPEIEQ----------KM 209 L+R +LG+ IRVN + P + T L + + P++E +M Sbjct: 184 GVVGLMRAFGVELGQHMIRVNSVHPTHVKTPMLHNEGTFKMFRPDLENPGPDDMAPICQM 243 Query: 210 LQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGGG 250 PI +P DI+NA LF S A +++G L + G Sbjct: 244 FHTLPIP-WVEPIDISNAVLFFASDEARYITGVTLPIDAGS 283 >1O5I-A nrPDB Length = 249 Score = 225 bits (575), Expect = 1e-59, Method: Composition-based stats. Identities = 67/246 (27%), Positives = 121/246 (49%), Gaps = 16/246 (6%) Query: 5 DNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFA 64 L + K ++ A GIG+ +A + GA V + N + Sbjct: 13 MELGIRDKGVLVLAASRGIGRAVADVLSQEGAEVTICARNEELLKR---------SGHRY 63 Query: 65 CRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFF 123 CD+ + D K+ +VDILV NAGG FD + DF+ A + + Sbjct: 64 VVCDLRKD------LDLLFEKVKEVDILVLNAGGPKAGFFDELTNEDFKEAIDSLFLNMI 117 Query: 124 HLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIR 183 + + P M++ G G I+ ITS + + N+ + S++ A + ++ ++F++ I Sbjct: 118 KIVRNYLPAMKEKGWGRIVAITSFSVISPIENLYTSNSARMALTGFLKTLSFEVAPYGIT 177 Query: 184 VNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQI 243 VN +APG T+ +K +++ E ++++ P+RR+ +P++IA+ FLCS AS+++GQ Sbjct: 178 VNCVAPGWTETERVKELLSEEKKKQVESQIPMRRMAKPEEIASVVAFLCSEKASYLTGQT 237 Query: 244 LTVSGG 249 + V GG Sbjct: 238 IVVDGG 243 >3U5T-A nrPDB Length = 267 Score = 225 bits (573), Expect = 2e-59, Method: Composition-based stats. Identities = 78/253 (30%), Positives = 125/253 (49%), Gaps = 5/253 (1%) Query: 1 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDI-NADAANHVVDEIQQLG 59 ++ + K AI+TGA GIG IA A+ G +VV++ A AA V +I+ G Sbjct: 18 LYFQSMME-TNKVAIVTGASRGIGAAIAARLASDGFTVVINYAGKAAAAEEVAGKIEAAG 76 Query: 60 GQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGG-PKPFDMPMADFRRAYELN 118 G+A + D++ + L A G VD+LVNNAG + A F R +N Sbjct: 77 GKALTAQADVSDPAAVRRLFATAEEAFGGVDVLVNNAGIMPLTTIAETGDAVFDRVIAVN 136 Query: 119 VFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLG 178 + F+ + A + GG I+ +++ + + YA++KA + ++ +L Sbjct: 137 LKGTFNTLREAAQRL--RVGGRIINMSTSQVGLLHPSYGIYAAAKAGVEAMTHVLSKELR 194 Query: 179 EKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASW 238 ++I VN +APG TD + E+ + + P+ RLG PQDIA A FL P +W Sbjct: 195 GRDITVNAVAPGPTATDLFLEGKSDEVRDRFAKLAPLERLGTPQDIAGAVAFLAGPDGAW 254 Query: 239 VSGQILTVSGGGV 251 V+GQ+L +GG + Sbjct: 255 VNGQVLRANGGII 267 >3T7C-A nrPDB Length = 299 Score = 223 bits (570), Expect = 4e-59, Method: Composition-based stats. Identities = 77/278 (27%), Positives = 130/278 (46%), Gaps = 31/278 (11%) Query: 4 SDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN------------ADAANHV 51 S +++GK A ITGA G G+ AIT A GA ++ D+ D Sbjct: 21 SMAGKVEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAET 80 Query: 52 VDEIQQLGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAG--GGGPKPFDMPMA 109 V +++ LG + A + D+ + A D +++LG++DI++ NA G + M Sbjct: 81 VRQVEALGRRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRMDPK 140 Query: 110 DFRRAYELNVFSFFHLSQLVAPE-MEKNGGGVILTITSMAAENKNINMTSYASSKAAASH 168 +R ++N+ + +++ P M GG I+ +S+ N+ +Y +SK Sbjct: 141 TWRDMIDVNLNGAWITARVAIPHIMAGKRGGSIVFTSSIGGLRGAENIGNYIASKHGLHG 200 Query: 169 LVRNMAFDLGEKNIRVNGIAPGAILTDAL---------------KSVITPEIEQKMLQHT 213 L+R MA +LG +NIRVN + P ++ T L +V ++ + + Sbjct: 201 LMRTMALELGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFQVASRQMHVL 260 Query: 214 PIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGGGV 251 PI +P DI+NA LFL S A +++G L V GG + Sbjct: 261 PIP-YVEPADISNAILFLVSDDARYITGVSLPVDGGAL 297 >1X1T-A nrPDB Length = 260 Score = 223 bits (570), Expect = 4e-59, Method: Composition-based stats. Identities = 68/259 (26%), Positives = 116/259 (44%), Gaps = 14/259 (5%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN--ADAANHVVDEIQQLGGQAFACR 66 L GK A++TG+ +GIG IA A GA +V++ A+ Q G + Sbjct: 2 LKGKVAVVTGSTSGIGLGIATALAAQGADIVLNGFGDAAEIEKVRAGLAAQHGVKVLYDG 61 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHL 125 D++ + + L D A+ ++G++DILVNNAG D P + LN+ + FH Sbjct: 62 ADLSKGEAVRGLVDNAVRQMGRIDILVNNAGIQHTALIEDFPTEKWDAILALNLSAVFHG 121 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 + P M+K G G I+ I S + N ++Y ++K + A + + I N Sbjct: 122 TAAALPHMKKQGFGRIINIASAHGLVASANKSAYVAAKHGVVGFTKVTALETAGQGITAN 181 Query: 186 GIAPGAILTDALKSVITP-----------EIEQKMLQHTPIRRLGQPQDIANAALFLCSP 234 I PG + T ++ I+ + + + P + P+ + A+FL S Sbjct: 182 AICPGWVRTPLVEKQISALAEKNGVDQETAARELLSEKQPSLQFVTPEQLGGTAVFLASD 241 Query: 235 AASWVSGQILTVSGGGVQE 253 AA+ ++G ++V GG Sbjct: 242 AAAQITGTTVSVDGGWTAR 260 >4CQM-B nrPDB Length = 244 Score = 223 bits (570), Expect = 5e-59, Method: Composition-based stats. Identities = 63/240 (26%), Positives = 104/240 (43%), Gaps = 10/240 (4%) Query: 11 GKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDIT 70 K + G GIG+ +A A G + V N + A LGG A CD+ Sbjct: 9 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAA---GDLGGDHLAFSCDVA 65 Query: 71 SEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQLV 129 E ++ + LG+V+ LVN AG D N+ + Sbjct: 66 KEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAA 125 Query: 130 APEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAP 189 M + GG I+ + S+ N + Y++SK R +A ++ K IRVN +AP Sbjct: 126 MRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAP 185 Query: 190 GAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 G + TD K + E+ + ++ P+ R G+ ++A+A +FL + +++G +L V GG Sbjct: 186 GFVHTDMTKDL----KEEHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGG 239 >3RWB-A nrPDB Length = 247 Score = 223 bits (569), Expect = 5e-59, Method: Composition-based stats. Identities = 83/248 (33%), Positives = 125/248 (50%), Gaps = 5/248 (2%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 RL GK A++TGA GIGK IA A GA+V+VSDINA+ A I G +A A Sbjct: 3 RLAGKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASI---GKKARAIAA 59 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGG-PKPFDMPMADFRRAYELNVFSFFHLS 126 DI+ + AL + G +DILVNNA D+ + +R+ ++N+ F ++ Sbjct: 60 DISDPGSVKALFAEIQALTGGIDILVNNASIVPFVAWDDVDLDHWRKIIDVNLTGTFIVT 119 Query: 127 QLVAPEMEKNGG-GVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 + +M G G +++I S NM +Y ++K R +A +LG+ NI N Sbjct: 120 RAGTDQMRAAGKAGRVISIASNTFFAGTPNMAAYVAAKGGVIGFTRALATELGKYNITAN 179 Query: 186 GIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILT 245 + PG I +D +K+ E + ++ GQP+ IA+ FL S A W++GQ L Sbjct: 180 AVTPGLIESDGVKASPHNEAFGFVEMLQAMKGKGQPEHIADVVSFLASDDARWITGQTLN 239 Query: 246 VSGGGVQE 253 V G V+ Sbjct: 240 VDAGMVRH 247 >1UZM-A nrPDB Length = 247 Score = 223 bits (569), Expect = 6e-59, Method: Composition-based stats. Identities = 68/240 (28%), Positives = 111/240 (46%), Gaps = 13/240 (5%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITS 71 + ++TG GIG IA A G V V+ + A + F D+T Sbjct: 16 RSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPKGL-----------FGVEVDVTD 64 Query: 72 EQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQLVA 130 + G V++LV+NAG M F + N+ F ++Q + Sbjct: 65 SDAVDRAFTAVEEHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRAS 124 Query: 131 PEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPG 190 M++N G ++ I S++ N +YA+SKA + R++A +L + N+ N +APG Sbjct: 125 RSMQRNKFGRMIFIGSVSGLWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAPG 184 Query: 191 AILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGGG 250 I TD +++ I+Q LQ P +R+G P ++A FL S AS++SG ++ V GG Sbjct: 185 YIDTDMTRAL-DERIQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISGAVIPVDGGM 243 >4HP8-A nrPDB Length = 247 Score = 222 bits (567), Expect = 9e-59, Method: Composition-based stats. Identities = 81/252 (32%), Positives = 122/252 (48%), Gaps = 10/252 (3%) Query: 5 DNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFA 64 + L+G+ A++TGA G+G+ IA+ A AGA VV + A + +D I + GG A A Sbjct: 3 NPFSLEGRKALVTGANTGLGQAIAVGLAAAGAEVVCAAR--RAPDETLDIIAKDGGNASA 60 Query: 65 CRCDITSEQELSALADFAISKLGKVDILVNNAGGGG-PKPFDMPMADFRRAYELNVFSFF 123 D A DILVNNAG + D+ ++N+ + F Sbjct: 61 LLIDFADPLAAKDSFTDA-----GFDILVNNAGIIRRADSVEFSELDWDEVMDVNLKALF 115 Query: 124 HLSQLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182 +Q A E+ G G ++ I S+ + I + SY ++K + L + +A + K I Sbjct: 116 FTTQAFAKELLAKGRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTKLLANEWAAKGI 175 Query: 183 RVNGIAPGAILTDALKSVITPEIEQK-MLQHTPIRRLGQPQDIANAALFLCSPAASWVSG 241 VN IAPG I T+ +++ K +L+ P R G +DIA AA+FL S AA +V G Sbjct: 176 NVNAIAPGYIETNNTEALRADAARNKAILERIPAGRWGHSEDIAGAAVFLSSAAADYVHG 235 Query: 242 QILTVSGGGVQE 253 IL V GG + Sbjct: 236 AILNVDGGWLAR 247 >1DOH-A nrPDB Length = 283 Score = 221 bits (563), Expect = 3e-58, Method: Composition-based stats. Identities = 77/262 (29%), Positives = 131/262 (50%), Gaps = 17/262 (6%) Query: 4 SDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINA-DAANHVVDEIQQLGGQA 62 + L+GK A++TGAG GIG+E+A+ G V+V+ N+ ++A VV I++ G A Sbjct: 22 PQSASLEGKVALVTGAGRGIGREMAMELGRRGCKVIVNYANSTESAEEVVAAIKKNGSDA 81 Query: 63 FACRCDITSEQELSALADFAISKLGKVDILVNNAGGGG-PKPFDMPMADFRRAYELNVFS 121 + ++ +++ + + A+ GK+DI+ +N+G D+ +F R + +N Sbjct: 82 ACVKANVGVVEDIVRMFEEAVKIFGKLDIVCSNSGVVSFGHVKDVTPEEFDRVFTINTRG 141 Query: 122 FFHLSQLVAPEMEKNGGGVILTITSMAAE-NKNINMTSYASSKAAASHLVRNMAFDLGEK 180 F +++ +E GG ++ + S+ + Y+ SK A R MA D+ +K Sbjct: 142 QFFVAREAYKHLE--IGGRLILMGSITGQAKAVPKHAVYSGSKGAIETFARCMAIDMADK 199 Query: 181 NIRVNGIAPGAILTDALKSVITPEI------------EQKMLQHTPIRRLGQPQDIANAA 228 I VN +APG I TD +V I E +Q +P+RR+G P DIA Sbjct: 200 KITVNVVAPGGIKTDMYHAVCREYIPNGENLSNEEVDEYAAVQWSPLRRVGLPIDIARVV 259 Query: 229 LFLCSPAASWVSGQILTVSGGG 250 FL S WV+G+++ + GG Sbjct: 260 CFLASNDGGWVTGKVIGIDGGA 281 >1K2W-A nrPDB Length = 256 Score = 221 bits (563), Expect = 3e-58, Method: Composition-based stats. Identities = 77/255 (30%), Positives = 122/255 (47%), Gaps = 15/255 (5%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 +RLDGK A+ITG+ GIG+ A + GA V ++DIN +AA EI G A A Sbjct: 1 MRLDGKTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAAEI---GPAACAIA 57 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHL 125 D+T + + + + G +DILVNNA P ++ + R + +NV + Sbjct: 58 LDVTDQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGTLFM 117 Query: 126 SQLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 Q VA M G GG I+ + S A + Y ++KAA L ++ +L I V Sbjct: 118 MQAVARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNLIRHGINV 177 Query: 185 NGIAPGAILTDA----------LKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSP 234 N IAPG + + +++ E ++++ P R+G+ +D+ A+FL +P Sbjct: 178 NAIAPGVVDGEHWDGVDAKFADYENLPRGEKKRQVGAAVPFGRMGRAEDLTGMAIFLATP 237 Query: 235 AASWVSGQILTVSGG 249 A ++ Q V GG Sbjct: 238 EADYIVAQTYNVDGG 252 >3UF0-A nrPDB Length = 273 Score = 219 bits (559), Expect = 7e-58, Method: Composition-based stats. Identities = 85/256 (33%), Positives = 132/256 (51%), Gaps = 6/256 (2%) Query: 2 FNSDN--LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLG 59 F S L G+ A++TGAG+GIG+ IA +A AGA V+ D V DEI G Sbjct: 20 FQSMTGPFSLAGRTAVVTGAGSGIGRAIAHGYARAGAHVLAWGRT-DGVKEVADEIADGG 78 Query: 60 GQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELN 118 G A A D+ + + +A+ + +VD+LVNNAG P + + + +R +N Sbjct: 79 GSAEAVVADLADLEGAANVAEELAAT-RRVDVLVNNAGIIARAPAEEVSLGRWREVLTVN 137 Query: 119 VFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLG 178 + + + LS+ M +G G I+TI SM + N+ +YA+SK A L R +A + Sbjct: 138 LDAAWVLSRSFGTAMLAHGSGRIVTIASMLSFQGGRNVAAYAASKHAVVGLTRALASEWA 197 Query: 179 EKNIRVNGIAPGAILTDALKSV-ITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAAS 237 + + VN +APG ++T ++ E ++ P R P+D+ A+FL S AAS Sbjct: 198 GRGVGVNALAPGYVVTANTAALRADDERAAEITARIPAGRWATPEDMVGPAVFLASDAAS 257 Query: 238 WVSGQILTVSGGGVQE 253 +V GQ+L V GG + Sbjct: 258 YVHGQVLAVDGGWLAS 273 >2CFC-A nrPDB Length = 250 Score = 219 bits (559), Expect = 8e-58, Method: Composition-based stats. Identities = 70/243 (28%), Positives = 113/243 (46%), Gaps = 6/243 (2%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDE-IQQLGGQAFACRCDIT 70 + AI+TGA +G G IA F G V D++A+ + R D+ Sbjct: 3 RVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYADKVLRVRADVA 62 Query: 71 SEQELSALADFAISKLGKVDILVNNAGGGGPK----PFDMPMADFRRAYELNVFSFFHLS 126 E +++A + + G +D+LVNNAG G P+ F + +NV F Sbjct: 63 DEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVRGIFLGC 122 Query: 127 QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNG 186 + V P M G GVI+ I S+A+ ++Y +SK A L +++A D IR N Sbjct: 123 RAVLPHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDYAGSGIRCNA 182 Query: 187 IAPGAILTDALKSVIT-PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILT 245 + PG I T + + PE+ ++L P + +G +A+A +FL A++V+G L Sbjct: 183 VCPGMIETPMTQWRLDQPELRDQVLARIPQKEIGTAAQVADAVMFLAGEDATYVNGAALV 242 Query: 246 VSG 248 + G Sbjct: 243 MDG 245 >3U4C-A nrPDB Length = 281 Score = 218 bits (557), Expect = 2e-57, Method: Composition-based stats. Identities = 65/260 (25%), Positives = 120/260 (46%), Gaps = 13/260 (5%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEI--QQLGGQAFAC 65 + + A + GA GIGK IA+ A S+V++ N D V ++I + Sbjct: 20 HMSKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVL 79 Query: 66 RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFH 124 D++ + + + S+ G++D+L+NN GG P FD + D + ++ Sbjct: 80 AGDMSDQHTRAGIFQKIESQCGRLDVLINNIPGGAPDTFDNCNIEDMTATFTQKTVAYID 139 Query: 125 LSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 + + M++N G I+ I + NM + + AA + +N++ L NI V Sbjct: 140 AIKRASSLMKQNEFGRIINIVGNLWKEPGANMFTNSMMNAALINASKNISIQLAPHNITV 199 Query: 185 NGIAPGAILTDALK----------SVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSP 234 N + PG I TD S+ + E+++ P++R+G ++ A A FL S Sbjct: 200 NCLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGIPMKRVGSAEETAALAAFLASE 259 Query: 235 AASWVSGQILTVSGGGVQEL 254 AS+++GQ ++ GG ++ + Sbjct: 260 EASYITGQQISADGGSMKSI 279 >3OIG-A nrPDB Length = 266 Score = 218 bits (556), Expect = 2e-57, Method: Composition-based stats. Identities = 61/254 (24%), Positives = 111/254 (43%), Gaps = 11/254 (4%) Query: 5 DNLRLDGKCAIITGAG--AGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQ- 61 N L+G+ ++ G I IA + AGA ++ + V + L Sbjct: 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRND 60 Query: 62 AFACRCDITSEQELSALADFAISKLGKVD-----ILVNNAGGGGPKPFDMPMADFRRAYE 116 + CD+T++ E+ ++G + I N + + F A+ Sbjct: 61 SIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHN 120 Query: 117 LNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFD 176 ++ +S + + P M + GG I+T+T + E N +KA+ V+ +A D Sbjct: 121 ISSYSLTAVVKAARPMMTE--GGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAAD 178 Query: 177 LGEKNIRVNGIAPGAILTDALKSVITPE-IEQKMLQHTPIRRLGQPQDIANAALFLCSPA 235 LG++NIRVN I+ G I T + K + I + + + P+RR P+++ + A FL S Sbjct: 179 LGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDM 238 Query: 236 ASWVSGQILTVSGG 249 + ++G+ L V G Sbjct: 239 SRGITGENLHVDSG 252 >4FC7-A nrPDB Length = 277 Score = 215 bits (548), Expect = 2e-56, Method: Composition-based stats. Identities = 76/254 (29%), Positives = 129/254 (50%), Gaps = 6/254 (2%) Query: 1 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQ-QLG 59 +F D LR K A ITG G+GIG IA F G V++ + ++ G Sbjct: 19 LFCPDLLR--DKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATG 76 Query: 60 GQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELN 118 + D+ + + A D A+ + G++DIL+N A G P + F+ +++ Sbjct: 77 RRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDID 136 Query: 119 VFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLG 178 F++S+++ + ++ GGVI+ IT+ S+KAA + R++A + G Sbjct: 137 TSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 196 Query: 179 EKNIRVNGIAPGAIL-TDALKSVITPEI-EQKMLQHTPIRRLGQPQDIANAALFLCSPAA 236 +NIRVN +APG I T+ L+ + P+ + +P++RLG +IA++ L+L SP A Sbjct: 197 PQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLA 256 Query: 237 SWVSGQILTVSGGG 250 S+V+G +L GG Sbjct: 257 SYVTGAVLVADGGA 270 >2HSD-A nrPDB Length = 253 Score = 215 bits (547), Expect = 2e-56, Method: Composition-based stats. Identities = 81/243 (33%), Positives = 117/243 (48%), Gaps = 5/243 (2%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 L GK IITG G+G E A AGA VV++D+ + E+ G A D Sbjct: 3 LSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATAREL---GDAARYQHLD 59 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDM-PMADFRRAYELNVFSFFHLSQ 127 +T E++ + +A + G VD LVNNAG + + FR+ E+N+ F + Sbjct: 60 VTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVEINLTGVFIGMK 119 Query: 128 LVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGI 187 V P M+ GGG I+ I+S A +SY +SK L + A +LG IRVN + Sbjct: 120 TVIPAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSV 179 Query: 188 APGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVS 247 PG T + E +TP+ R+G+P +IA A + L S +S+V+G L V Sbjct: 180 HPGMTYTPMTAETGIRQGEGNY-PNTPMGRVGEPGEIAGAVVKLLSDTSSYVTGAELAVD 238 Query: 248 GGG 250 GG Sbjct: 239 GGW 241 >4E6P-A nrPDB Length = 259 Score = 214 bits (546), Expect = 3e-56, Method: Composition-based stats. Identities = 75/258 (29%), Positives = 120/258 (46%), Gaps = 15/258 (5%) Query: 4 SDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAF 63 S RL+GK A+ITG+ GIG+ A + GA+V ++DI+ + A EI G A+ Sbjct: 1 SMMKRLEGKSALITGSARGIGRAFAEAYVREGATVAIADIDIERARQAAAEI---GPAAY 57 Query: 64 ACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSF 122 A + D+T + + A + G +DILVNNA P ++ + + + +NV Sbjct: 58 AVQMDVTRQDSIDAAIAATVEHAGGLDILVNNAALFDLAPIVEITRESYEKLFAINVAGT 117 Query: 123 FHLSQLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKN 181 Q A +M G GG I+ + S A + Y ++KAA L ++ DL + Sbjct: 118 LFTLQAAARQMIAQGRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAGLDLIKHR 177 Query: 182 IRVNGIAPGAILTDALKSV----------ITPEIEQKMLQHTPIRRLGQPQDIANAALFL 231 I VN IAPG + + V E ++ + + P R+G +D+ A+FL Sbjct: 178 INVNAIAPGVVDGEHWDGVDALFARYENRPRGEKKRLVGEAVPFGRMGTAEDLTGMAIFL 237 Query: 232 CSPAASWVSGQILTVSGG 249 S + ++ Q V GG Sbjct: 238 ASAESDYIVSQTYNVDGG 255 >5EJ2-A nrPDB Length = 308 Score = 214 bits (545), Expect = 3e-56, Method: Composition-based stats. Identities = 70/274 (25%), Positives = 118/274 (43%), Gaps = 31/274 (11%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN------------ADAANHVVDEI 55 R+ GK A I+GA G G+ A+ A GA ++ DI + D + Sbjct: 34 RVAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETADLV 93 Query: 56 QQLGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGP--KPFDMPMADFRR 113 + L + + D+ + L + D + +LG++DI+V NAG G K + ++ Sbjct: 94 KDLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTDGRKLHKIRDNVWQD 153 Query: 114 AYELNVFSFFHLSQLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRN 172 ++N+ +H + P + G GG I+ +S+ N Y ++K L+R Sbjct: 154 MIDINLTGVWHTVKAGVPHVLSGGRGGSIVLTSSVGGRKAYPNTGHYIAAKHGVIGLMRA 213 Query: 173 MAFDLGEKNIRVNGIAPGAILT-----DALKSVITPEIE----------QKMLQHTPIRR 217 A +LG IRVN + P + T D + P++E +M+ P+ Sbjct: 214 FAVELGPHMIRVNAVLPTQVSTTMVMNDQTFRLFRPDLENPGPDDFAPISQMMHTLPVP- 272 Query: 218 LGQPQDIANAALFLCSPAASWVSGQILTVSGGGV 251 DI+NA LFL S + +V+G L V G + Sbjct: 273 WVDASDISNAVLFLASDESRYVTGVSLPVDAGSL 306 >5YCX-A nrPDB Length = 266 Score = 213 bits (543), Expect = 6e-56, Method: Composition-based stats. Identities = 66/250 (26%), Positives = 114/250 (45%), Gaps = 11/250 (4%) Query: 9 LDGKCAIITGAG--AGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQL-GGQAFAC 65 L GK ++ G I IA + AGA ++ + +V + L G ++ Sbjct: 6 LQGKTFVVMGVANQRSIAWGIARSLHNAGAKLIFTYAGERLERNVRELADTLEGQESLVL 65 Query: 66 RCDITSEQELSALADFAISKLGKVD-----ILVNNAGGGGPKPFDMPMADFRRAYELNVF 120 CD+T+++EL+A + ++G + I N + D F A ++ F Sbjct: 66 PCDVTNDEELTACFETIKQEVGTIHGVAHCIAFANRDDLKGEFVDTSRDGFLLAQNISAF 125 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 S +++ M + GG ILT+T + E N +KA+ V+ +A DLG+ Sbjct: 126 SLTAVAREAKKVMTE--GGNILTLTYLGGERVVKNYNVMGVAKASLEASVKYLANDLGQH 183 Query: 181 NIRVNGIAPGAILTDALKSVITPE-IEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 IRVN I+ G I T + K V I +++ + P+RR +++ + A+FL S A V Sbjct: 184 GIRVNAISAGPIRTLSAKGVGDFNSILREIEERAPLRRTTTQEEVGDTAVFLFSDLARGV 243 Query: 240 SGQILTVSGG 249 +G+ + V G Sbjct: 244 TGENIHVDSG 253 >5B1Y-A nrPDB Length = 270 Score = 213 bits (542), Expect = 7e-56, Method: Composition-based stats. Identities = 65/248 (26%), Positives = 130/248 (52%), Gaps = 6/248 (2%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN-ADAANHVVDEIQQLGG-QAFAC 65 ++ A++TG GIG+ + FA G SVV++ + AD A +E ++LG +A+ Sbjct: 20 HMETTYALVTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAEEARRLGSPEAYTV 79 Query: 66 RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFH 124 R D+ ++ ++ + +++LVN AG + ++++ +N+ + Sbjct: 80 RVDVGDPDSVTEMSSRVGELIPHLNVLVNAAGVLQLGGIEETSISEWEETLRVNLTGVYL 139 Query: 125 LSQLVAPEMEKNGGGVILTITSMAAENKNI-NMTSYASSKAAASHLVRNMAFDLGEKNIR 183 +++L+ P + K I+ + S+A E N+ +Y++SKA L + +A L IR Sbjct: 140 VTKLLLPLLRKAKWASIVNVASIAGETGNVVAGVAYSASKAGVIGLTKRLAVQLAGYGIR 199 Query: 184 VNGIAPGAILTDALKSVIT-PEIEQKMLQHTPIRRLGQPQDIANAALFLCSP-AASWVSG 241 VN +AP + TD +S + PE +++ P++ + +P+D+A A LFL P + ++G Sbjct: 200 VNAVAPSFVETDMTRSFLDTPEKRERIASLHPLKIILKPEDVAEAILFLADPRRSRGITG 259 Query: 242 QILTVSGG 249 +L+++ G Sbjct: 260 HVLSINAG 267 >3V8B-A nrPDB Length = 283 Score = 213 bits (542), Expect = 7e-56, Method: Composition-based stats. Identities = 75/262 (28%), Positives = 123/262 (46%), Gaps = 12/262 (4%) Query: 1 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG 60 ++ + A+ITGAG+GIG+ A+ A G +V V DEI GG Sbjct: 18 LYFQSMMNQPSPVALITGAGSGIGRATALALAADGVTVGALGRTRTEVEEVADEIVGAGG 77 Query: 61 QAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGG--PKPFDMPMADFRRAYELN 118 QA A D++ E ++ + K G +DI+V NAG G D+ ++ +N Sbjct: 78 QAIALEADVSDELQMRNAVRDLVLKFGHLDIVVANAGINGVWAPIDDLKPFEWDETIAVN 137 Query: 119 VFSFFHLSQLVAPEMEKNGGGVILTITSMAAEN--KNINMTSYASSKAAASHLVRNMAFD 176 + F L P +++ GGG I+ ++S+ T+Y ++KAA +V+ +A + Sbjct: 138 LRGTFLTLHLTVPYLKQRGGGAIVVVSSINGTRTFTTPGATAYTATKAAQVAIVQQLALE 197 Query: 177 LGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQ------HTPI--RRLGQPQDIANAA 228 LG+ +IRVN + PGAI T+ + E+ + PI + G+ +D+A Sbjct: 198 LGKHHIRVNAVCPGAIETNISDNTKLRHEEETAIPVEWPKGQVPITDGQPGRSEDVAELI 257 Query: 229 LFLCSPAASWVSGQILTVSGGG 250 FL S A V+G + + GG Sbjct: 258 RFLVSERARHVTGSPVWIDGGQ 279 >2YW9-A nrPDB Length = 261 Score = 212 bits (541), Expect = 1e-55, Method: Composition-based stats. Identities = 74/249 (29%), Positives = 119/249 (47%), Gaps = 11/249 (4%) Query: 9 LDGKCAIITGAG--AGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 L GK A++ G +G IA AGA V +S + LGG A R Sbjct: 6 LSGKKALVMGVTNQRSLGFAIAAKLKEAGAEVALSYQAERLRPEAEKLAEALGG-ALLFR 64 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGG-----PKPFDMPMADFRRAYELNVFS 121 D+T ++EL AL G +D LV+ + D D+ A E++ +S Sbjct: 65 ADVTQDEELDALFAGVKEAFGGLDYLVHAIAFAPREAMEGRYIDTRRQDWLLALEVSAYS 124 Query: 122 FFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKN 181 +++ P + + GG I+T+T A+E A +KAA VR +A++LG K Sbjct: 125 LVAVARRAEPLLREGGG--IVTLTYYASEKVVPKYNVMAIAKAALEASVRYLAYELGPKG 182 Query: 182 IRVNGIAPGAILTDALKSVITP-EIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVS 240 +RVN I+ G + T A +S+ ++ ++ Q P+RR +++ N LFL SP AS ++ Sbjct: 183 VRVNAISAGPVRTVAARSIPGFTKMYDRVAQTAPLRRNITQEEVGNLGLFLLSPLASGIT 242 Query: 241 GQILTVSGG 249 G+++ V G Sbjct: 243 GEVVYVDAG 251 >5TF4-A nrPDB Length = 274 Score = 211 bits (539), Expect = 2e-55, Method: Composition-based stats. Identities = 69/249 (27%), Positives = 114/249 (45%), Gaps = 11/249 (4%) Query: 9 LDGKCAIITGAG--AGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 L GK +I G I IA T ++AGA + + V +++ G Sbjct: 10 LYGKRGLILGLANNRSIAWGIAKTASSAGAELAFTYQGEAMKKRVEPLAEEVKGFVCGH- 68 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-----DMPMADFRRAYELNVFS 121 CD++ + A+ + K GK+D LV+ G + D+ ++F ++V+S Sbjct: 69 CDVSDSASIDAVFNTIEKKWGKLDFLVHAIGFSDKEELSGRYVDISESNFMMTMNISVYS 128 Query: 122 FFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKN 181 L++ M + GG ILT+T AE N +KAA V+ +A DLG K+ Sbjct: 129 LTALTKRAEKLM--SDGGSILTLTYYGAEKVVPNYNVMGVAKAALEASVKYLAVDLGPKH 186 Query: 182 IRVNGIAPGAILTDALKSVITPEIEQKMLQ-HTPIRRLGQPQDIANAALFLCSPAASWVS 240 IRVN I+ G I T A + K + + P+RR +++ ++AL+L S + V+ Sbjct: 187 IRVNAISAGPIKTLAASGIGDFRYILKWNEYNAPLRRTVTIEEVGDSALYLLSDLSRSVT 246 Query: 241 GQILTVSGG 249 G++ V G Sbjct: 247 GEVHHVDSG 255 >4ZJU-A nrPDB Length = 275 Score = 211 bits (537), Expect = 3e-55, Method: Composition-based stats. Identities = 68/250 (27%), Positives = 111/250 (44%), Gaps = 11/250 (4%) Query: 9 LDGKCAIITGAGA--GIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 L GK +I G + I IA GA + + N + VDE + G Sbjct: 14 LAGKRFLIAGVASKLSIAYGIAQALHREGAELAFTYPN-EKLKKRVDEFAEQFGSKLVFP 72 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD------MPMADFRRAYELNVF 120 CD+ + E+ VD +V++ G D F+ A++++ + Sbjct: 73 CDVAVDAEIDNAFAELAKHWDGVDGVVHSIGFAPAHTLDGDFTDVTDRDGFKIAHDISAY 132 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 SF +++ P ++ G +LT+T +E N +KA+ VR +A LG Sbjct: 133 SFVAMARAAKPLLQARQ-GCLLTLTYQGSERVMPNYNVMGMAKASLEAGVRYLASSLGVD 191 Query: 181 NIRVNGIAPGAILTDALKSVIT-PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 IRVN I+ G I T A + + ++ + P++R +++ NAALFLCSP AS + Sbjct: 192 GIRVNAISAGPIRTLAASGIKSFRKMLDANEKVAPLKRNVTIEEVGNAALFLCSPWASGI 251 Query: 240 SGQILTVSGG 249 +G+IL V G Sbjct: 252 TGEILYVDAG 261 >3D3W-A nrPDB Length = 244 Score = 211 bits (537), Expect = 3e-55, Method: Composition-based stats. Identities = 71/248 (28%), Positives = 114/248 (45%), Gaps = 11/248 (4%) Query: 5 DNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFA 64 L L G+ ++TGAG GIG+ GA VV + +V E G + Sbjct: 1 MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVREC--PGIEPVC 58 Query: 65 CRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFF 123 D+ + G VD+LVNNA +PF ++ F R++E+N+ + Sbjct: 59 V--DLGDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVI 112 Query: 124 HLSQLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182 +SQ+VA + G G I+ ++S ++ N + Y S+K A L + MA +LG I Sbjct: 113 QVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKI 172 Query: 183 RVNGIAPGAILTDALKSVI-TPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSG 241 RVN + P ++T ++ P + ML P+ + + + + NA LFL S + +G Sbjct: 173 RVNAVNPTVVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTG 232 Query: 242 QILTVSGG 249 L V GG Sbjct: 233 STLPVEGG 240 >2B4Q-A nrPDB Length = 276 Score = 210 bits (535), Expect = 5e-55, Method: Composition-based stats. Identities = 70/250 (28%), Positives = 119/250 (47%), Gaps = 8/250 (3%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 L G+ A++TG GIG+ IA AGA V + +A+A + G A Sbjct: 25 FSLAGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYG-DCQAIP 83 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFHL 125 D++SE LA ++DILVNNAG + P++ + + +LNV S F Sbjct: 84 ADLSSEAGARRLAQALGELSARLDILVNNAGTSWGAALESYPVSGWEKVMQLNVTSVFSC 143 Query: 126 SQLVAPEMEKNGG----GVILTITSMAAENKNINMT-SYASSKAAASHLVRNMAFDLGEK 180 Q + P + ++ ++ I S+A + +Y SKAA L R +A +L + Sbjct: 144 IQQLLPLLRRSASAENPARVINIGSVAGISAMGEQAYAYGPSKAALHQLSRMLAKELVGE 203 Query: 181 NIRVNGIAPGAILTDALKSVI-TPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 +I VN IAPG + + + P+ + P+ R G+P+++A A+ L A +++ Sbjct: 204 HINVNVIAPGRFPSRMTRHIANDPQALEADSASIPMGRWGRPEEMAALAISLAGTAGAYM 263 Query: 240 SGQILTVSGG 249 +G ++ + GG Sbjct: 264 TGNVIPIDGG 273 >3GDF-A nrPDB Length = 267 Score = 210 bits (534), Expect = 6e-55, Method: Composition-based stats. Identities = 69/252 (27%), Positives = 120/252 (47%), Gaps = 9/252 (3%) Query: 5 DNLRLDGKCAIITGAG--AGIGKEIAITFATAGASVVVSDIN-ADAANHVVDEIQQ-LGG 60 D L L GK ++TGA G+G E A A GA+V ++ + A A V E+++ G Sbjct: 14 DQLSLKGKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKTYGI 73 Query: 61 QAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPK-PFDMPMADFRRAYELNV 119 +A A +C + S + L ++ G++D + NAG D + + ++++ Sbjct: 74 KAKAYKCQVDSYESCEKLVKDVVADFGQIDAFIANAGATADSGILDGSVEAWNHVVQVDL 133 Query: 120 FSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNI--NMTSYASSKAAASHLVRNMAFDL 177 FH ++ V ++ G G ++ SM+ N TSY +KA H+ R++A + Sbjct: 134 NGTFHCAKAVGHHFKERGTGSLVITASMSGHIANFPQEQTSYNVAKAGCIHMARSLANEW 193 Query: 178 GEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAAS 237 RVN I+PG I T L + E +Q P+ R G +++ A ++ S A++ Sbjct: 194 -RDFARVNSISPGYIDT-GLSDFVPKETQQLWHSMIPMGRDGLAKELKGAYVYFASDAST 251 Query: 238 WVSGQILTVSGG 249 + +G L + GG Sbjct: 252 YTTGADLLIDGG 263 >5KOI-A nrPDB Length = 293 Score = 210 bits (534), Expect = 6e-55, Method: Composition-based stats. Identities = 66/250 (26%), Positives = 106/250 (42%), Gaps = 12/250 (4%) Query: 9 LDGKCAIITGAG--AGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 + GK +I G + IA A GA + + DA V + + G F Sbjct: 26 MQGKRGLIMGVANNHSLAWGIAKQLAAQGAELAFTYQG-DALGKRVKPLAEQVGSDFVLP 84 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD------MPMADFRRAYELNVF 120 CD+ + A+ + K G +D LV+ G +F R ++ + Sbjct: 85 CDVEDIATVDAVFEEIEKKWGGLDFLVHAIGFSDKTELKGRYADVTTRENFSRTMVISAY 144 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 SF ++Q M+ GG ILT+T + N +KAA +VR +A D G + Sbjct: 145 SFTEVAQRAEKLMKD--GGSILTLTYGGSTRTIPNYNVMGVAKAALEAMVRYLAADYGPQ 202 Query: 181 NIRVNGIAPGAILTDALKSVITPE-IEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 IRVN I+ G + T A + I +++P+RR D+ +A++L S +S V Sbjct: 203 GIRVNAISAGPVRTLAGAGIGDARAIFSYQRRNSPLRRTVDIDDVGKSAVYLLSDLSSGV 262 Query: 240 SGQILTVSGG 249 +G+I V G Sbjct: 263 TGEIHFVDSG 272 >3K2E-A nrPDB Length = 296 Score = 209 bits (532), Expect = 1e-54, Method: Composition-based stats. Identities = 58/251 (23%), Positives = 107/251 (42%), Gaps = 11/251 (4%) Query: 7 LRLDGKCAIITGAG--AGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFA 64 + ++GK +I G + IA GA V ++ ++ + VD + + G Sbjct: 26 MLMEGKKGVIIGVANDKSLAWGIAKAVCAQGAEVALTYLS-ETFKKRVDPLAESLGVKLT 84 Query: 65 CRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-----DMPMADFRRAYELNV 119 CD++ + + + + G +D +V+ D + +F + ++ Sbjct: 85 VPCDVSDAESVDNMFKVLAEEWGSLDFVVHAVAFSDKNELKGRYVDTSLGNFLTSMHISC 144 Query: 120 FSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGE 179 +SF +++ P M GG ILT++ AE + KAA V+ +A DLG+ Sbjct: 145 YSFTYIASKAEPLMT--NGGSILTLSYYGAEKVVPHYNVMGVCKAALEASVKYLAVDLGK 202 Query: 180 KNIRVNGIAPGAILTDALKSVITPEIEQKMLQ-HTPIRRLGQPQDIANAALFLCSPAASW 238 + IRVN I+ G + T A + + ++P+RR D+ AAL+L S Sbjct: 203 QQIRVNAISAGPVRTLASSGISDFHYILTWNKYNSPLRRNTTLDDVGGAALYLLSDLGRG 262 Query: 239 VSGQILTVSGG 249 +G+ + V G Sbjct: 263 TTGETVHVDCG 273 >5JY1-A nrPDB Length = 274 Score = 208 bits (531), Expect = 1e-54, Method: Composition-based stats. Identities = 75/245 (30%), Positives = 124/245 (50%), Gaps = 4/245 (1%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 L+ + A++TGAG GIG+ +A +F GA+V++++IN V EI+++GG++ + D Sbjct: 12 LEQRVALVTGAGGGIGRGVARSFGNEGAAVIIAEINESTGRQVEQEIREMGGRSLFVKTD 71 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD--FRRAYELNVFSFFHLS 126 +TS+ + A A+ + G +DILVNNA P D + ++++ + Sbjct: 72 VTSKASIEAAVRSAVEQFGSLDILVNNAFVPTPNVLLEEKTDEMLEQTLTTSLWATWWAM 131 Query: 127 QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNG 186 + M + G I+ S+ E Y ++KA L R+ A + G NI VN Sbjct: 132 RAAFVPMRERRWGRIVNFYSIDTETGAWLHGDYNTAKAGIVGLTRSAASEWGRFNITVNA 191 Query: 187 IAPGAI-LTDALKSVITPEIEQKMLQHTPIRRLGQPQ-DIANAALFLCSPAASWVSGQIL 244 IAP A+ T + PE ++ P+ R G P+ DI AA+F S + +V+G+ L Sbjct: 192 IAPTAMGATFFELAAKNPEFAERSAAARPLGRSGDPEQDIGPAAVFFASEMSRFVTGETL 251 Query: 245 TVSGG 249 V GG Sbjct: 252 HVDGG 256 >3GRK-A nrPDB Length = 293 Score = 207 bits (528), Expect = 3e-54, Method: Composition-based stats. Identities = 69/249 (27%), Positives = 106/249 (42%), Gaps = 11/249 (4%) Query: 9 LDGKCAIITGAG--AGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 L GK +I G I IA AGA + + DA V+ + + G A Sbjct: 29 LQGKRGLILGVANNRSIAWGIAKAAREAGAELAFTYQG-DALKKRVEPLAEELGAFVAGH 87 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGG-----PKPFDMPMADFRRAYELNVFS 121 CD+ + A+ + K GK+D LV+ G + D A+F ++V+S Sbjct: 88 CDVADAASIDAVFETLEKKWGKLDFLVHAIGFSDKDELTGRYIDTSEANFTNTMLISVYS 147 Query: 122 FFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKN 181 +S+ M GG ILT+T AE N +KAA V+ +A DLG +N Sbjct: 148 LTAVSRRAEKLM--ADGGSILTLTYYGAEKVMPNYNVMGVAKAALEASVKYLAVDLGPQN 205 Query: 182 IRVNGIAPGAILTDALKSVITPEIEQKMLQ-HTPIRRLGQPQDIANAALFLCSPAASWVS 240 IRVN I+ G I T A + K + + P+RR ++ + L+ S + V+ Sbjct: 206 IRVNAISAGPIKTLAASGIGDFRYILKWNEYNAPLRRTVTIDEVGDVGLYFLSDLSRSVT 265 Query: 241 GQILTVSGG 249 G++ G Sbjct: 266 GEVHHADSG 274 >4NR0-A nrPDB Length = 273 Score = 207 bits (527), Expect = 4e-54, Method: Composition-based stats. Identities = 70/251 (27%), Positives = 113/251 (45%), Gaps = 11/251 (4%) Query: 9 LDGKCAIITGAGA--GIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQA-FAC 65 L GK A+I G + I IA GA + + N V + G + Sbjct: 4 LTGKRALIVGVASKLSIASGIAAAMHREGAELAFTYQNDKLRGRVEEFASGWGSRPELCF 63 Query: 66 RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD------MPMADFRRAYELNV 119 CD+ + ++ A+ +DI+V++ G D FR A++++ Sbjct: 64 PCDVADDSQIEAVFAALGKHWDGLDIIVHSVGFAPGDQLDGDFTAVTTREGFRIAHDISA 123 Query: 120 FSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGE 179 +SF L++ EM K G +LT++ + AE N +KA+ VR +A LG Sbjct: 124 YSFIALAK-AGREMMKGRNGSLLTLSYLGAERTMPNYNVMGMAKASLEAGVRYLAGSLGA 182 Query: 180 KNIRVNGIAPGAILTDALKSVIT-PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASW 238 + RVN ++ G I T A + + ++ + TP+RR +++ NA FLCS AS Sbjct: 183 EGTRVNAVSAGPIRTLAASGIKSFRKMLAANERQTPLRRNVTIEEVGNAGAFLCSDLASG 242 Query: 239 VSGQILTVSGG 249 +SG+IL V GG Sbjct: 243 ISGEILYVDGG 253 >1HXH-A nrPDB Length = 253 Score = 207 bits (527), Expect = 4e-54, Method: Composition-based stats. Identities = 78/248 (31%), Positives = 124/248 (50%), Gaps = 11/248 (4%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 RL GK A++TG +G+G E+ GA V SDIN A + E+ G ++ R Sbjct: 3 RLQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAEL---GERSMFVRH 59 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDM-PMADFRRAYELNVFSFFHLS 126 D++SE + + + +LG +++LVNNAG P + + DF R ++N S F Sbjct: 60 DVSSEADWTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRLEDFSRLLKINTESVFIGC 119 Query: 127 QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKN--IRV 184 Q M++ GG I+ + S+++ Y++SKAA S L R A ++ IRV Sbjct: 120 QQGIAAMKET-GGSIINMASVSSWLPIEQYAGYSASKAAVSALTRAAALSCRKQGYAIRV 178 Query: 185 NGIAPGAILTDALKSVITPEIEQKMLQHTP-IRRLGQ---PQDIANAALFLCSPAASWVS 240 N I P I T +++ + + ++M+ H P + R G+ P+ IA LFL S +S +S Sbjct: 179 NSIHPDGIYTPMMQASLPKGVSKEMVLHDPKLNRAGRAYMPERIAQLVLFLASDESSVMS 238 Query: 241 GQILTVSG 248 G L Sbjct: 239 GSELHADN 246 >3A28-C nrPDB Length = 258 Score = 206 bits (525), Expect = 6e-54, Method: Composition-based stats. Identities = 72/254 (28%), Positives = 121/254 (47%), Gaps = 14/254 (5%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDI--NADAANHVVDEIQQLGGQAFACRCDI 69 K A++TG GIG+ I+ A G + V+D+ + A + I+ +A D+ Sbjct: 3 KVAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQEEQAAETIKLIEAADQKAVFVGLDV 62 Query: 70 TSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQL 128 T + + D A KLG D+LVNNAG KP ++ D ++ Y +NVFS F Q Sbjct: 63 TDKANFDSAIDEAAEKLGGFDVLVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQA 122 Query: 129 VAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGI 187 + + ++ G G I+ S+AA +++Y+++K A L + A +L K VN Sbjct: 123 ASRKFDELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQELAPKGHTVNAY 182 Query: 188 APGAILTDALKSVITP----------EIEQKMLQHTPIRRLGQPQDIANAALFLCSPAAS 237 APG + T + + E ++ + R P+D+A FL S ++ Sbjct: 183 APGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLASENSN 242 Query: 238 WVSGQILTVSGGGV 251 +V+GQ++ V GG + Sbjct: 243 YVTGQVMLVDGGML 256 >4AVY-A nrPDB Length = 242 Score = 206 bits (524), Expect = 9e-54, Method: Composition-based stats. Identities = 83/243 (34%), Positives = 126/243 (51%), Gaps = 13/243 (5%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDI 69 G+ ++TG +GIG IA+ FA GA VV ++AD + + DI Sbjct: 10 AGQQVLVTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHAP------RHPRIRREELDI 63 Query: 70 TSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLV 129 T Q L L + ++D+LVNNAG + + +A F R LN+ + SQL Sbjct: 64 TDSQRLQRLFEALP----RLDVLVNNAGISRDRE-EYDLATFERVLRLNLSAAMLASQLA 118 Query: 130 APEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAP 189 P + GG IL I SM + + + +Y++SK A L R++A + + IRVN IAP Sbjct: 119 RPLL-AQRGGSILNIASMYSTFGSADRPAYSASKGAIVQLTRSLACEYAAERIRVNAIAP 177 Query: 190 GAILTDALKSVITP-EIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSG 248 G I T + E ++++Q TP+ R G+ ++A+AA FLC P AS+V+G +L V G Sbjct: 178 GWIDTPLGAGLKADVEATRRIMQRTPLARWGEAPEVASAAAFLCGPGASFVTGAVLAVDG 237 Query: 249 GGV 251 G + Sbjct: 238 GYL 240 >1CYD-A nrPDB Length = 244 Score = 205 bits (523), Expect = 1e-53, Method: Composition-based stats. Identities = 79/252 (31%), Positives = 126/252 (50%), Gaps = 11/252 (4%) Query: 5 DNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFA 64 L G A++TGAG GIG++ +GA VV + E G + Sbjct: 1 MKLNFSGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKEC--PGIEPVC 58 Query: 65 CRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFF 123 D+ + A+ +G VD+LVNNA +PF ++ F R++ +N+ S F Sbjct: 59 V--DLGDWD----ATEKALGGIGPVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNLRSVF 112 Query: 124 HLSQLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182 +SQ+VA +M G G I+ ++SM A N+ +Y+S+K A + L + MA +LG I Sbjct: 113 QVSQMVARDMINRGVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMELGPHKI 172 Query: 183 RVNGIAPGAILTDALKSVI-TPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSG 241 RVN + P +LTD K V PE +K+ + P+R+ + +D+ N+ LFL S ++ SG Sbjct: 173 RVNSVNPTVVLTDMGKKVSADPEFARKLKERHPLRKFAEVEDVVNSILFLLSDRSASTSG 232 Query: 242 QILTVSGGGVQE 253 + V G + Sbjct: 233 GGILVDAGYLAS 244 >3UN1-A nrPDB Length = 260 Score = 205 bits (521), Expect = 2e-53, Method: Composition-based stats. Identities = 70/253 (27%), Positives = 117/253 (46%), Gaps = 18/253 (7%) Query: 1 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG 60 ++ +R K +ITGA GIG + + VV + + + Sbjct: 18 LYFQSMMRNQQKVVVITGASQGIGAGLVRAYRDRNYRVVATSRSIKPSAD---------P 68 Query: 61 QAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNV 119 DI+ + + I + G++D LVNNAG KPF +M D+ +NV Sbjct: 69 DIHTVAGDISKPETADRIVREGIERFGRIDSLVNNAGVFLAKPFVEMTQEDYDHNLGVNV 128 Query: 120 FSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASS--KAAASHLVRNMAFDL 177 FFH++Q A EM K G G I++IT+ + + M S +S K + + R++A + Sbjct: 129 AGFFHITQRAAAEMLKQGSGHIVSITTSLVDQPMVGMPSALASLTKGGLNAVTRSLAMEF 188 Query: 178 GEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAAS 237 +RVN ++PG I T + E + P+ R+G+ +D+ +A L+L A Sbjct: 189 SRSGVRVNAVSPGVIKTPMHPA----ETHSTLAGLHPVGRMGEIRDVVDAVLYL--EHAG 242 Query: 238 WVSGQILTVSGGG 250 +++G+IL V GG Sbjct: 243 FITGEILHVDGGQ 255 >5CFZ-A nrPDB Length = 305 Score = 205 bits (521), Expect = 2e-53, Method: Composition-based stats. Identities = 65/250 (26%), Positives = 111/250 (44%), Gaps = 12/250 (4%) Query: 9 LDGKCAIITGAGA--GIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 L GK ++TG + I IA GA + + N V + QLG + Sbjct: 47 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSD-IVLQ 105 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD------MPMADFRRAYELNVF 120 CD+ + + + K D V++ G D + F+ A++++ + Sbjct: 106 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSY 165 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 SF +++ + N G +LT++ + AE N +KA+ VR MA +G + Sbjct: 166 SFVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 223 Query: 181 NIRVNGIAPGAILTDALKSVIT-PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 +RVN I+ G I T A + ++ TPIRR +D+ N+A FLCS ++ + Sbjct: 224 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 283 Query: 240 SGQILTVSGG 249 SG+++ V GG Sbjct: 284 SGEVVHVDGG 293 >1H5Q-A nrPDB Length = 265 Score = 203 bits (517), Expect = 7e-53, Method: Composition-based stats. Identities = 73/255 (28%), Positives = 128/255 (50%), Gaps = 11/255 (4%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEI-QQLGGQAFAC 65 + K I+TG GIG A AGA+V V +A A V +++ ++ G + A Sbjct: 10 ISFVNKTIIVTGGNRGIGLAFTRAVAAAGANVAVIYRSAADAVEVTEKVGKEFGVKTKAY 69 Query: 66 RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFH 124 +CD+++ ++ + LG + L+ NAG KP ++ DF Y++NVF F+ Sbjct: 70 QCDVSNTDIVTKTIQQIDADLGPISGLIANAGVSVVKPATELTHEDFAFVYDVNVFGVFN 129 Query: 125 LSQLVAPE-MEKNGGGVILTITSMAAE-------NKNINMTSYASSKAAASHLVRNMAFD 176 + VA ++K G I+ +SM+++ N ++ Y SSKAA S+LV+ +A + Sbjct: 130 TCRAVAKLWLQKQQKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSSKAACSNLVKGLAAE 189 Query: 177 LGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAA 236 IRVN ++PG + TD + +I + P+ R QP+++ A+ L S A Sbjct: 190 WASAGIRVNALSPGYVNTDQTAH-MDKKIRDHQASNIPLNRFAQPEEMTGQAILLLSDHA 248 Query: 237 SWVSGQILTVSGGGV 251 ++++G + GG + Sbjct: 249 TYMTGGEYFIDGGQL 263 >2FWM-X nrPDB Length = 250 Score = 203 bits (516), Expect = 8e-53, Method: Composition-based stats. Identities = 67/255 (26%), Positives = 119/255 (46%), Gaps = 20/255 (7%) Query: 6 NLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFAC 65 ++ GK +TGAG GIG A+ F AGA V + + + Sbjct: 2 HMDFSGKNVWVTGAGKGIGYATALAFVEAGAKV--TGFDQAFTQEQYPFATE-------- 51 Query: 66 RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFH 124 D+ +++ + +++ ++D LVN AG D + D+++ + +NV F+ Sbjct: 52 VMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 111 Query: 125 LSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 L Q + + GG I+T+ S AA I M++Y +SKAA L ++ +L +R Sbjct: 112 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 171 Query: 185 NGIAPGAILTDALKSVITPE---------IEQKMLQHTPIRRLGQPQDIANAALFLCSPA 235 N ++PG+ TD +++ + ++ P+ ++ +PQ+IAN LFL S Sbjct: 172 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 231 Query: 236 ASWVSGQILTVSGGG 250 AS ++ Q + V GG Sbjct: 232 ASHITLQDIVVDGGS 246 >2AG5-A nrPDB Length = 246 Score = 202 bits (515), Expect = 9e-53, Method: Composition-based stats. Identities = 69/250 (27%), Positives = 123/250 (49%), Gaps = 16/250 (6%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 RLDGK I+T A GIG+ A+ FA GA V+ +DIN E+++ G Sbjct: 3 RLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQ----ELEKYPGIQTRV-L 57 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGP-KPFDMPMADFRRAYELNVFSFFHLS 126 D+T ++++ A +++ ++D+L N AG D D+ + LNV S + + Sbjct: 58 DVTKKKQIDQFA----NEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113 Query: 127 QLVAPEMEKNGGGVILTITSMAAE-NKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 + P+M G I+ ++S+A+ +N Y+++KAA L +++A D ++ IR N Sbjct: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173 Query: 186 GIAPGAILTDALKSVI-----TPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVS 240 + PG + T +L+ I E L+ R ++IA ++L S +++V+ Sbjct: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVT 233 Query: 241 GQILTVSGGG 250 G + + GG Sbjct: 234 GNPVIIDGGW 243 >4JQC-A nrPDB Length = 282 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 65/250 (26%), Positives = 111/250 (44%), Gaps = 12/250 (4%) Query: 9 LDGKCAIITGAGA--GIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 L GK ++TG + I IA GA + + N V + QLG + Sbjct: 24 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSD-IVLQ 82 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD------MPMADFRRAYELNVF 120 CD+ + + + K D V++ G D + F+ A++++ + Sbjct: 83 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSY 142 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 SF +++ + N G +LT++ + AE N +KA+ VR MA +G + Sbjct: 143 SFVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 200 Query: 181 NIRVNGIAPGAILTDALKSVIT-PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 +RVN I+ G I T A + ++ TPIRR +D+ N+A FLCS ++ + Sbjct: 201 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 260 Query: 240 SGQILTVSGG 249 SG+++ V GG Sbjct: 261 SGEVVHVDGG 270 >4TRR-A nrPDB Length = 269 Score = 201 bits (513), Expect = 2e-52, Method: Composition-based stats. Identities = 80/256 (31%), Positives = 135/256 (52%), Gaps = 13/256 (5%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 L+GK A++TGA +GIGKEIA+ A AGA+V ++D+N D AN V DEI + GG+A Sbjct: 11 NLNGKTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANAVADEINKAGGKAIGVAM 70 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFHLS 126 D+T+E+ ++ D G VDILV+NAG P + AD+++ ++V F + Sbjct: 71 DVTNEEAVNTGIDKVAEAFGSVDILVSNAGIQIVNPIENYSFADWKKMQAIHVDGAFLTT 130 Query: 127 QLVAPEM-EKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 + M + + GGV++ + S+ + + ++Y ++K L R +A + + N+R + Sbjct: 131 KAALKHMYKDDRGGVVIYMGSVHSHEASPLKSAYVTAKHGLLGLARVLAKEGAKHNVRSH 190 Query: 186 GIAPGAILTDALKSVITPE-----------IEQKMLQHTPIRRLGQPQDIANAALFLCSP 234 + PG + T + I + I++ ML +T QD+A LFL + Sbjct: 191 VVCPGFVRTPLVDKQIPEQAKELGISEEEVIKKVMLGNTVDGVFTTVQDVAQTVLFLSAF 250 Query: 235 AASWVSGQILTVSGGG 250 ++ ++GQ VS G Sbjct: 251 PSAALTGQSFIVSHGW 266 >5JS6-A nrPDB Length = 274 Score = 199 bits (507), Expect = 9e-52, Method: Composition-based stats. Identities = 67/231 (29%), Positives = 112/231 (48%), Gaps = 15/231 (6%) Query: 28 AITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQELSALADFAISKLG 87 F +GA VV+ D + + E+ A CD+T E ++ L I + G Sbjct: 28 VRAFVNSGARVVICDKDESGGRALEQEL----PGAVFILCDVTQEDDVKTLVSETIRRFG 83 Query: 88 KVDILVNNAGGGGP--KPFDMPMADFRRAYELNVFSFFHLSQLVAPEMEKNGGGVILTIT 145 ++D +VNNAG P +P + FR+ ELN+ + L++L P + K+ G ++ I+ Sbjct: 84 RLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQ-GNVINIS 142 Query: 146 SMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVI---- 201 S+ Y ++K A + + + +A D +RVN I+PG I T + + Sbjct: 143 SLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMP 202 Query: 202 --TPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGGG 250 I + ML P+ R+GQP ++ AA+FL S A++ +G L V+GG Sbjct: 203 DPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLAS-EANFCTGIELLVTGGA 251 >4M89-A nrPDB Length = 261 Score = 199 bits (506), Expect = 1e-51, Method: Composition-based stats. Identities = 62/250 (24%), Positives = 108/250 (43%), Gaps = 11/250 (4%) Query: 9 LDGKCAIITG--AGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 L GK +ITG + I IA GA + + + V +L + R Sbjct: 4 LQGKKILITGMISERSIAYGIAKACREQGAELAFTYVVDKLEERVRKMAAELDSE-LVFR 62 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD------MPMADFRRAYELNVF 120 CD+ S+ E++ + +D LV++ G + + F A+E++ + Sbjct: 63 CDVASDDEINQVFADLGKHWDGLDGLVHSIGFAPKEALSGDFLDSISREAFNTAHEISAY 122 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 S L++ P M + I+ ++ + A N +KA+ +R A LG++ Sbjct: 123 SLPALAKAARP-MMRGRNSAIVALSYLGAVRAIPNYNVMGMAKASLEAGIRFTAACLGKE 181 Query: 181 NIRVNGIAPGAILTDALKSVITP-EIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 IR NGI+ G I T A + ++ + H P+RR +++ N A FL S +S + Sbjct: 182 GIRCNGISAGPIKTLAASGIADFGKLLGHVAAHNPLRRNVTIEEVGNTAAFLLSDLSSGI 241 Query: 240 SGQILTVSGG 249 +G+I V GG Sbjct: 242 TGEITYVDGG 251 >5I9N-A nrPDB Length = 276 Score = 198 bits (505), Expect = 2e-51, Method: Composition-based stats. Identities = 62/250 (24%), Positives = 116/250 (46%), Gaps = 12/250 (4%) Query: 9 LDGKCAIITG--AGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 LDGK ++TG + I IA GA + + + + + + + G + Sbjct: 4 LDGKRILLTGLLSNRSIAYGIAKACKREGAELAFTYVGDRFKDRITEFAAEFGSE-LVFP 62 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF------DMPMADFRRAYELNVF 120 CD+ + ++ AL + +D LV++ G + + +FR A++++ + Sbjct: 63 CDVADDAQIDALFASLKTHWDSLDGLVHSIGFAPREAIAGDFLDGLTRENFRIAHDISAY 122 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 SF L++ P + + +LT++ + AE N + +KAA VR +A LG K Sbjct: 123 SFPALAKAALPMLSDD--ASLLTLSYLGAERAIPNYNTMGLAKAALEASVRYLAVSLGAK 180 Query: 181 NIRVNGIAPGAILTDALKSVITP-EIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWV 239 +RVN I+ G I T A + + +I + ++P++R + + NA FL S AS V Sbjct: 181 GVRVNAISAGPIKTLAASGIKSFGKILDFVESNSPLKRNVTIEQVGNAGAFLLSDLASGV 240 Query: 240 SGQILTVSGG 249 + +++ V G Sbjct: 241 TAEVMHVDSG 250 >4ALL-A nrPDB Length = 277 Score = 198 bits (504), Expect = 2e-51, Method: Composition-based stats. Identities = 59/253 (23%), Positives = 107/253 (42%), Gaps = 11/253 (4%) Query: 6 NLRLDGKCAIITGAG--AGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG-QA 62 L L+ K +I G I +A GA +V + + + ++QL +A Sbjct: 22 MLNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEA 81 Query: 63 FACRCDITSEQELSALADFAISKLGKVD-----ILVNNAGGGGPKPFDMPMADFRRAYEL 117 + D+ S++E+ + +G +D I N + + F A ++ Sbjct: 82 HLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDI 141 Query: 118 NVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDL 177 + +S ++ M + GG I+ T + E N +KA+ V+ +A DL Sbjct: 142 SSYSLTIVAHEAKKLMPE--GGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDL 199 Query: 178 GEKNIRVNGIAPGAILTDALKSVITPE-IEQKMLQHTPIRRLGQPQDIANAALFLCSPAA 236 G NIRVN I+ G I T + K V I +++ + P++R ++ A +L S + Sbjct: 200 GPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLS 259 Query: 237 SWVSGQILTVSGG 249 S V+G+ + V G Sbjct: 260 SGVTGENIHVDSG 272 >5O3Z-A nrPDB Length = 263 Score = 197 bits (501), Expect = 4e-51, Method: Composition-based stats. Identities = 69/255 (27%), Positives = 123/255 (48%), Gaps = 15/255 (5%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQL--GGQAFACRCDI 69 + A++ G G +G + A AG V V+D+N AN + D I G+A+ + D Sbjct: 7 QVAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTINSRYGAGRAYGFKVDA 66 Query: 70 TSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFHLSQL 128 T E + ALA G+ D+LV +AG P + DF + ++N+ +F S+ Sbjct: 67 TDEASVEALARAVDETFGRADLLVYSAGVAKAAPITQFRLTDFDLSLQVNLVGYFLCSRE 126 Query: 129 VAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGI 187 + M ++G G I+ I S + + + + + Y+++K L +++A DL E I V+ + Sbjct: 127 FSKLMIRDGIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDLAEYGITVHSL 186 Query: 188 APG-AILTDALKSVIT----------PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAA 236 G + + +S++ E+E + P++R QD+ N LF S A Sbjct: 187 MLGNLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPLKRGCDYQDVLNVLLFYASDKA 246 Query: 237 SWVSGQILTVSGGGV 251 ++ +GQ + V+GG V Sbjct: 247 AYCTGQSINVTGGQV 261 >4EGF-A nrPDB Length = 266 Score = 195 bits (497), Expect = 1e-50, Method: Composition-based stats. Identities = 82/247 (33%), Positives = 123/247 (49%), Gaps = 4/247 (1%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEI-QQLGGQAFAC 65 LRLDGK A+ITGA GIG +IA FA AGA +V+S + + + +Q G Sbjct: 16 LRLDGKRALITGATKGIGADIARAFAAAGARLVLSGRDVSELDAARRALGEQFGTDVHTV 75 Query: 66 RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELNVFSFFH 124 D+ + LA A G +D+LVNNAG P+P D F +N+ + Sbjct: 76 AIDLAEPDAPAELARRAAEAFGGLDVLVNNAGISHPQPVVDTDPQLFDATIAVNLRAPAL 135 Query: 125 LSQLVAPEMEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIR 183 L+ V M G GG I+T+ S AA + +Y +SKA + +A +LG IR Sbjct: 136 LASAVGKAMVAAGEGGAIITVASAAALAPLPDHYAYCTSKAGLVMATKVLARELGPHGIR 195 Query: 184 VNGIAPGAILTDALKSVITPEIEQK-MLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQ 242 N + P +LT+ + V E + M+ P+ R P ++++A ++L S AAS ++G Sbjct: 196 ANSVCPTVVLTEMGQRVWGDEAKSAPMIARIPLGRFAVPHEVSDAVVWLASDAASMINGV 255 Query: 243 ILTVSGG 249 + V GG Sbjct: 256 DIPVDGG 262 >3ZV3-A nrPDB Length = 281 Score = 191 bits (486), Expect = 2e-49, Method: Composition-based stats. Identities = 74/260 (28%), Positives = 117/260 (45%), Gaps = 21/260 (8%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 ++L G+ A+ITG +G+G+ + F GA V V D +A+ + GG A Sbjct: 1 MKLTGEVALITGGASGLGRALVDRFVAEGARVAVLDKSAERLRELE---VAHGGNAVGVV 57 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGG------GGPKPFDMPMADFRRAYELNVF 120 D+ S Q+ A+ ++ GK+D L+ NAG P D A F + +NV Sbjct: 58 GDVRSLQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDIFHVNVK 117 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 + H + P + + G V+ TI S A N Y ++K A LVR MAF+L Sbjct: 118 GYIHAVKACLPALVSSRGSVVFTI-SNAGFYPNGGGPLYTATKHAVVGLVRQMAFELAPH 176 Query: 181 NIRVNGIAPGAILTDA---------LKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFL 231 +RVNG+APG + TD +S+ + + + PI R+ ++ A +F Sbjct: 177 -VRVNGVAPGGMNTDLRGPSSLGLSEQSISSVPLADMLKSVLPIGRMPALEEYTGAYVFF 235 Query: 232 CSPAASW-VSGQILTVSGGG 250 + S +G +L GG Sbjct: 236 ATRGDSLPATGALLNYDGGM 255 >4NK4-A nrPDB Length = 301 Score = 191 bits (486), Expect = 3e-49, Method: Composition-based stats. Identities = 58/249 (23%), Positives = 104/249 (41%), Gaps = 11/249 (4%) Query: 9 LDGKCAIITGAG--AGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 L GK +I G I IA +AGA + S + + F Sbjct: 39 LKGKRGLIMGVANDHSIAWGIAKVLHSAGAQLAFSYQGESIGKRL-KPLALTVDSDFMIP 97 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-----MPMADFRRAYELNVFS 121 C++ + L + + +D +V++ +F + ++ FS Sbjct: 98 CNVEDPSSMDLLFERIKERWETLDFVVHSIAFSDKNELRGPYYNTSRDNFIQTMLVSCFS 157 Query: 122 FFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKN 181 F + + A M GG ++T+T + N + A +K+A + +A D G N Sbjct: 158 FTEIVRRAAQLMP--HGGAMITLTYGGSMRVVPNYNAMAPAKSALESSTKYLACDYGGMN 215 Query: 182 IRVNGIAPGAILTDALKSVIT-PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVS 240 IR+N I+ G + T A S+ +I +++P++R +DI N+AL+L S ++ V+ Sbjct: 216 IRINAISAGPVRTLAGASISNGRDIAAWSKENSPLKRTVSLEDIGNSALYLLSYLSNGVT 275 Query: 241 GQILTVSGG 249 G+I V G Sbjct: 276 GEIHYVDCG 284 >4RGB-A nrPDB Length = 294 Score = 191 bits (485), Expect = 3e-49, Method: Composition-based stats. Identities = 69/269 (25%), Positives = 114/269 (42%), Gaps = 26/269 (9%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINA------------DAANHVVDEI 55 LDG+ ITGA G G+ A+ A GA++V DI + + Sbjct: 22 SLDGRVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEETARLV 81 Query: 56 QQLGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMP-MADFRRA 114 ++ G + + D+ + L + D + + G +D ++ NAG P + R Sbjct: 82 EKTGQEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLTNPDERDASEALRLG 141 Query: 115 YELNVFSFFHLSQLVAPEMEKNG-GGVILTITSMAAEN----KNINMTSYASSKAAASHL 169 ++ + ++ Q+ P M++ G GG ++ +SM A +Y +SK A + L Sbjct: 142 LDIMLIGVWNTFQVAIPHMKERGQGGNLIATSSMIALLDLTDGRGGTDAYLTSKLAITGL 201 Query: 170 VRNMAFDLGEKNIRVNGIAPGAILTDALKSVI--------TPEIEQKMLQHTPIRRLGQP 221 VR+ A L IRVNG+AP T + P + M P + +P Sbjct: 202 VRSYALMLAADRIRVNGVAPTNCSTPMITENPALFKVIEENPHLVNAMSTALPDFPMIEP 261 Query: 222 QDIANAALFLCSPAASWVSGQILTVSGGG 250 +D++NA LFL S A +G +L V G Sbjct: 262 RDVSNAILFLISDAGRSFTGSVLKVDAGM 290 >4J3F-A nrPDB Length = 280 Score = 188 bits (477), Expect = 2e-48, Method: Composition-based stats. Identities = 57/250 (22%), Positives = 105/250 (42%), Gaps = 12/250 (4%) Query: 9 LDGKCAIITG--AGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 L GK +ITG + I IA GA + + + V+++ A Sbjct: 24 LAGKKILITGLLSNKSIAYGIAKAMHREGAELAFTYVGQ--FKDRVEKLCAEFNPAAVLP 81 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD------MPMADFRRAYELNVF 120 CD+ S+QE+ L +D +V++ + + F A++++ + Sbjct: 82 CDVISDQEIKDLFVELGKVWDGLDAIVHSIAFAPRDQLEGNFIDCVTREGFSIAHDISAY 141 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 SF L++ M KN ++ +T + AE + + +KA+ VR A LGE Sbjct: 142 SFAALAKE-GRSMMKNRNASMVALTYIGAEKAMPSYNTMGVAKASLEATVRYTALALGED 200 Query: 181 NIRVNGIAPGAILTDALKSVITPEIEQKMLQHT-PIRRLGQPQDIANAALFLCSPAASWV 239 I+VN ++ G I T A + + P+++ ++ N FLCS A+ + Sbjct: 201 GIKVNAVSAGPIKTLAASGISNFKKMLDYNAMVSPLKKNVDIMEVGNTVAFLCSDMATGI 260 Query: 240 SGQILTVSGG 249 +G+++ V G Sbjct: 261 TGEVVHVDAG 270 >3PXX-A nrPDB Length = 287 Score = 188 bits (477), Expect = 2e-48, Method: Composition-based stats. Identities = 64/281 (22%), Positives = 113/281 (40%), Gaps = 40/281 (14%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADA------------ANHVVDEI 55 R+ K ++TG G G+ A+ A GA +++ DI D E+ Sbjct: 7 RVQDKVVLVTGGARGQGRSHAVKLAEEGADIILFDICHDIETNEYPLATSRDLEEAGLEV 66 Query: 56 QQLGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAY 115 ++ G +A+ D+ +S A+++ GK+D++V NAG P +P+ F A+ Sbjct: 67 EKTGRKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANAGI-CPLGAHLPVQAFADAF 125 Query: 116 ELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAE-----------NKNINMTSYASSKA 164 +++ + P + G I+T S+A + Y+ +K Sbjct: 126 DVDFVGVINTVHAALPYLTS--GASIITTGSVAGLIAAAQPPGAGGPQGPGGAGYSYAKQ 183 Query: 165 AASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSV-----ITPEIE-----QKMLQHTP 214 +A L ++IR N I P + TD L S P++E +L Sbjct: 184 LVDSYTLQLAAQLAPQSIRANVIHPTNVNTDMLNSAPMYRQFRPDLEAPSRADALLAFPA 243 Query: 215 IRRLGQP----QDIANAALFLCSPAASWVSGQILTVSGGGV 251 ++ + P DI+NA FL S + +V+G V G + Sbjct: 244 MQAMPTPYVEASDISNAVCFLASDESRYVTGLQFKVDAGAM 284 >4CR6-A nrPDB Length = 271 Score = 187 bits (475), Expect = 4e-48, Method: Composition-based stats. Identities = 78/256 (30%), Positives = 119/256 (46%), Gaps = 14/256 (5%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 RL GK AI+TGA GIG+ + GASVV D+ A +E A C Sbjct: 12 RLAGKAAIVTGAAGGIGRATVEAYLREGASVVAMDLAPRLAATRYEEPG-----AIPIAC 66 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAG--GGGPKPFDMPMADFRRAYELNVFSFFHL 125 D+ + A A+++LG +DILV GG D+ AD+ R ++N+ F Sbjct: 67 DLADRAAIDAAMADAVARLGGLDILVAGGALKGGTGNFLDLSDADWDRYVDVNMTGTFLT 126 Query: 126 SQLVAPEMEKNGGG------VILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGE 179 + A M G G I+TI S+ + +Y ++K + L R MA DL Sbjct: 127 CRAGARAMVAAGAGKDGRSARIITIGSVNSFMAEPEAAAYVAAKGGVAMLTRAMAVDLAR 186 Query: 180 KNIRVNGIAPGAIL-TDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASW 238 I VN IAPG + T P + +++L + R G P+++A AA+FL +S+ Sbjct: 187 HGILVNMIAPGPVDVTGNNTGYSEPRLAEQVLDEVALGRPGLPEEVATAAVFLAEDGSSF 246 Query: 239 VSGQILTVSGGGVQEL 254 ++G +T+ GG + Sbjct: 247 ITGSTITIDGGLSAMI 262 >2BGM-A nrPDB Length = 278 Score = 187 bits (475), Expect = 4e-48, Method: Composition-based stats. Identities = 64/233 (27%), Positives = 111/233 (47%), Gaps = 9/233 (3%) Query: 28 AITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQELSALADFAISKLG 87 A F GA VV++DI D V + I +F CD+T ++++ L D I+K G Sbjct: 33 AKLFVRYGAKVVIADIADDHGQKVCNNIGSPDVISFVH-CDVTKDEDVRNLVDTTIAKHG 91 Query: 88 KVDILVNNAGGGGPKP---FDMPMADFRRAYELNVFSFFHLSQLVAPEMEKNGGGVILTI 144 K+DI+ N G P + DF+R ++NV+ F +++ A M G I+ Sbjct: 92 KLDIMFGNVGVLSTTPYSILEAGNEDFKRVMDINVYGAFLVAKHAARVMIPAKKGSIVFT 151 Query: 145 TSMAAENKNINM-TSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVITP 203 S+++ + Y ++K A L ++ +LGE IRVN ++P + + L V Sbjct: 152 ASISSFTAGEGVSHVYTATKHAVLGLTTSLCTELGEYGIRVNCVSPYIVASPLLTDVFGV 211 Query: 204 E---IEQKMLQHTPI-RRLGQPQDIANAALFLCSPAASWVSGQILTVSGGGVQ 252 + +E+ Q + L + +D+A+A +L + +VSG L + GG + Sbjct: 212 DSSRVEELAHQAANLKGTLLRAEDVADAVAYLAGDESKYVSGLNLVIDGGYTR 264 >1BDB-A nrPDB Length = 277 Score = 186 bits (473), Expect = 8e-48, Method: Composition-based stats. Identities = 68/259 (26%), Positives = 114/259 (44%), Gaps = 21/259 (8%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 ++L G+ +ITG +G+G+ + F GA V V D +A+ + G Sbjct: 1 MKLKGEAVLITGGASGLGRALVDRFVAEGAKVAVLDKSAERLAELET---DHGDNVLGIV 57 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGG--GGPKPFDMPMA----DFRRAYELNVF 120 D+ S ++ A +++ GK+D L+ NAG D+P F + +NV Sbjct: 58 GDVRSLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHINVK 117 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 + H + P + + G VI TI S A N Y ++K A LVR +AF+L Sbjct: 118 GYIHAVKACLPALVASRGNVIFTI-SNAGFYPNGGGPLYTAAKHAIVGLVRELAFELAPY 176 Query: 181 NIRVNGIAPGAILTDA---------LKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFL 231 +RVNG+ G I +D K++ T + + PI R+ + ++ A +F Sbjct: 177 -VRVNGVGSGGINSDLRGPSSLGMGSKAISTVPLADMLKSVLPIGRMPEVEEYTGAYVFF 235 Query: 232 CSP-AASWVSGQILTVSGG 249 + A+ +G +L GG Sbjct: 236 ATRGDAAPATGALLNYDGG 254 >2X9N-A nrPDB Length = 288 Score = 184 bits (468), Expect = 3e-47, Method: Composition-based stats. Identities = 66/267 (24%), Positives = 110/267 (41%), Gaps = 29/267 (10%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN-ADAANHVVDEI-QQLGGQAFAC 65 ++ A++TGA IG+ IA+ G VV+ N A+AA + DE+ ++ A C Sbjct: 20 HMEAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVC 79 Query: 66 RCDITS----EQELSALADFAISKLGKVDILVNNAGGGGPKPF-----------DMPMAD 110 + D+T+ + + G+ D+LVNNA P P Sbjct: 80 QADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDNSNGKTVETQ 139 Query: 111 FRRAYELNVFSFFHLS-------QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSK 163 N + F L+ + P + I+ + + + + Y K Sbjct: 140 VAELIGTNAIAPFLLTMSFAQRQKGTNPNCTSSNL-SIVNLCDAMVDQPCMAFSLYNMGK 198 Query: 164 AAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIR-RLGQPQ 222 A L ++ A +L IRVNG+APG L + E + K + P+ R + Sbjct: 199 HALVGLTQSAALELAPYGIRVNGVAPGV---SLLPVAMGEEEKDKWRRKVPLGRREASAE 255 Query: 223 DIANAALFLCSPAASWVSGQILTVSGG 249 IA+A +FL S +A +++G I+ V GG Sbjct: 256 QIADAVIFLVSGSAQYITGSIIKVDGG 282 >1W73-A nrPDB Length = 302 Score = 184 bits (467), Expect = 3e-47, Method: Composition-based stats. Identities = 69/247 (27%), Positives = 120/247 (48%), Gaps = 5/247 (2%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQ-QLGGQAFACR 66 GK A ITG G G+GK + ++ GA V++ D ++I Q G + A + Sbjct: 23 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 82 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFHL 125 CD+ + I G +I++NNA G P + + ++ ++ + + Sbjct: 83 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 142 Query: 126 SQLVAPEMEK-NGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 + + ++ K G L+IT++ AE + + AS+KA + +++A + G+ +R Sbjct: 143 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 202 Query: 185 NGIAPGAILTDALKSVITP--EIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQ 242 N I PG I T S + P E++M+ P RLG +++AN A FLCS ASW++G Sbjct: 203 NVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWINGA 262 Query: 243 ILTVSGG 249 ++ GG Sbjct: 263 VIKFDGG 269 >2GDZ-A nrPDB Length = 267 Score = 184 bits (467), Expect = 4e-47, Method: Composition-based stats. Identities = 57/212 (26%), Positives = 97/212 (45%), Gaps = 17/212 (8%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQ--LGGQAFACR 66 ++GK A++TGA GIG+ A GA V + D N +A + + + + Sbjct: 5 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLFIQ 64 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLS 126 CD+ +Q+L + G++DILVNNAG ++ + ++N+ S + Sbjct: 65 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN-------NEKNWEKTLQINLVSVISGT 117 Query: 127 QLVAPEMEKNGGG---VILTITSMAAENKNINMTSYASSKAAASHLVRN--MAFDLGEKN 181 L M K GG +I+ ++S+A Y +SK R+ +A +L Sbjct: 118 YLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSG 177 Query: 182 IRVNGIAPGAILTDALKSVITPEIEQKMLQHT 213 +R+N I PG + T L+S+ E E+ M Q+ Sbjct: 178 VRLNAICPGFVNTAILESI---EKEENMGQYI 206 >4DA9-A nrPDB Length = 280 Score = 183 bits (464), Expect = 7e-47, Method: Composition-based stats. Identities = 66/257 (25%), Positives = 108/257 (42%), Gaps = 8/257 (3%) Query: 1 MFNSDNLRLDGK-CAIITGAGAGIGKEIAITFATAGASVVVSDI-NADAANHVVDEIQQL 58 ++ + + AI+TG GIG IA A +G + ++ I +A+ V+ E+ L Sbjct: 18 LYFQSMMTQKARPVAIVTGGRRGIGLGIARALAASGFDIAITGIGDAEGVAPVIAELSGL 77 Query: 59 GGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGG---GPKPFDMPMADFRRAY 115 G + R D+ A D +++ G++D LVNNAG D+ +F Sbjct: 78 GARVIFLRADLADLSSHQATVDAVVAEFGRIDCLVNNAGIASIVRDDFLDLKPENFDTIV 137 Query: 116 ELNVFSFFHLSQLVAPEMEK---NGGGVILTITSMAAENKNINMTSYASSKAAASHLVRN 172 +N+ +Q V M I+ ITS++A + Y SKA + + Sbjct: 138 GVNLRGTVFFTQAVLKAMLASDARASRSIINITSVSAVMTSPERLDYCMSKAGLAAFSQG 197 Query: 173 MAFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLC 232 +A L E I V + PG I +D +V P+RR G+P+DI N L Sbjct: 198 LALRLAETGIAVFEVRPGIIRSDMTAAVSGKYDGLIESGLVPMRRWGEPEDIGNIVAGLA 257 Query: 233 SPAASWVSGQILTVSGG 249 + +G ++ GG Sbjct: 258 GGQFGFATGSVIQADGG 274 >3OML-A nrPDB Length = 613 Score = 181 bits (461), Expect = 2e-46, Method: Composition-based stats. Identities = 71/248 (28%), Positives = 115/248 (46%), Gaps = 28/248 (11%) Query: 6 NLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDI---------NADAANHVVDEIQ 56 LR DG+ A++TGAGAG+G+E A+ FA GA VVV+D+ + AA+ VVDEI+ Sbjct: 14 KLRYDGRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIR 73 Query: 57 QLGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGP-KPFDMPMADFRRAY 115 + GG+A A D S + + + + AI G+VDILVNNAG D+ Sbjct: 74 KAGGEAVA---DYNSVIDGAKVIETAIKAFGRVDILVNNAGILRDRSLVKTSEQDWNLVN 130 Query: 116 ELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAF 175 ++++ F +Q P M+K G I+ +S + N +Y ++K L +A Sbjct: 131 DVHLKGSFKCTQAAFPYMKKQNYGRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLANTVAI 190 Query: 176 DLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFL---- 231 + N+ N I P A + + ++ + ++ IA +L Sbjct: 191 EGARNNVLCNVIVPTA-ASRMTEGILPDILFNELKPKL----------IAPVVAYLCHES 239 Query: 232 CSPAASWV 239 C S++ Sbjct: 240 CEDNGSYI 247 >4GKB-A nrPDB Length = 258 Score = 181 bits (459), Expect = 3e-46, Method: Composition-based stats. Identities = 73/252 (28%), Positives = 116/252 (46%), Gaps = 10/252 (3%) Query: 5 DNLRLDGKCAIITGAGAGIGKEIAITFATAGAS-VVVSDINADAANHVVDEIQQLGGQAF 63 +L L K I+TG +GIG I++ A A VV + D A +D + Q +A Sbjct: 1 MDLNLQDKVVIVTGGASGIGGAISMRLAEERAIPVVFARHAPDGA--FLDALAQRQPRAT 58 Query: 64 ACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFF 123 ++ + + I+ G++D LVNNAG D F + E N+ ++ Sbjct: 59 YLPVELQDDAQCRDAVAQTIATFGRLDGLVNNAGVNDGIGLDAGRDAFVASLERNLIHYY 118 Query: 124 HLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIR 183 ++ P ++ G I+ I+S A N + Y +SK A L R A L E +R Sbjct: 119 AMAHYCVPHLKATR-GAIVNISSKTAVTGQGNTSGYCASKGAQLALTREWAVALREHGVR 177 Query: 184 VNGIAPGAILTDALKSVI----TPEIE-QKMLQHTPIR-RLGQPQDIANAALFLCSPAAS 237 VN + P ++T ++ I PE + ++ P+ R P +IA+ A+FL SP AS Sbjct: 178 VNAVIPAEVMTPLYRNWIATFEDPEAKLAEIAAKVPLGRRFTTPDEIADTAVFLLSPRAS 237 Query: 238 WVSGQILTVSGG 249 +G+ L V GG Sbjct: 238 HTTGEWLFVDGG 249 >2PD3-A nrPDB Length = 275 Score = 179 bits (454), Expect = 1e-45, Method: Composition-based stats. Identities = 62/249 (24%), Positives = 113/249 (45%), Gaps = 11/249 (4%) Query: 9 LDGKCAIITGAG--AGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 L GK +I G I IA + GA++ + +N V Q+L + Sbjct: 4 LKGKKGLIVGVANNKSIAYGIAQSCFNQGATLAFTYLNESLEKRVRPIAQELN-SPYVYE 62 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGG-----PKPFDMPMADFRRAYELNVFS 121 D++ E+ +L + LG +D +V++ + + F A E++V+S Sbjct: 63 LDVSKEEHFKSLYNSVKKDLGSLDFIVHSVAFAPKEALEGSLLETSKSAFNTAMEISVYS 122 Query: 122 FFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKN 181 L+ + P + N G +LT++ + + + +KAA VR +A DLG+ + Sbjct: 123 LIELTNTLKPLL--NNGASVLTLSYLGSTKYMAHYNVMGLAKAALESAVRYLAVDLGKHH 180 Query: 182 IRVNGIAPGAILTDALKSVITPEIEQKMLQ-HTPIRRLGQPQDIANAALFLCSPAASWVS 240 IRVN ++ G I T A + + K + + P+R+ +++ NA ++L S +S VS Sbjct: 181 IRVNALSAGPIRTLASSGIADFRMILKWNEINAPLRKNVSLEEVGNAGMYLLSSLSSGVS 240 Query: 241 GQILTVSGG 249 G++ V G Sbjct: 241 GEVHFVDAG 249 >2O23-A nrPDB Length = 265 Score = 176 bits (447), Expect = 8e-45, Method: Composition-based stats. Identities = 70/257 (27%), Positives = 116/257 (45%), Gaps = 20/257 (7%) Query: 6 NLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFAC 65 + G A+ITG +G+G A GAS V+ D+ + ++LG Sbjct: 7 CRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEA---QAKKLGNNCVFA 63 Query: 66 RCDITSEQELSALADFAISKLGKVDILVNNAGGGGP-------KPFDMPMADFRRAYELN 118 D+TSE+++ A K G+VD+ VN AG K + DF+R ++N Sbjct: 64 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 123 Query: 119 VFSFFHLSQLVAPEMEKN------GGGVILTITSMAAENKNINMTSYASSKAAASHLVRN 172 + F++ +LVA EM +N GVI+ S+AA + +Y++SK + Sbjct: 124 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLP 183 Query: 173 MAFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIR-RLGQPQDIANAALFL 231 +A DL IRV IAPG T L S+ ++ + P RLG P + A+ + Sbjct: 184 IARDLAPIGIRVMTIAPGLFGTPLLTSL-PEKVCNFLASQVPFPSRLGDPAEYAHLVQAI 242 Query: 232 CSPAASWVSGQILTVSG 248 +++G+++ + G Sbjct: 243 IENP--FLNGEVIRLDG 257 >5IZ4-A nrPDB Length = 271 Score = 175 bits (444), Expect = 2e-44, Method: Composition-based stats. Identities = 67/254 (26%), Positives = 122/254 (48%), Gaps = 17/254 (6%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVS---DINADAANHVVDEIQQLGGQAFACRCDI 69 +ITG+ +GIG A+ FA AG SV + D DAA+ V + G Q D+ Sbjct: 16 VCVITGSASGIGAATALRFAQAGWSVAIGNFDDSTRDAASTVEALCRDAGAQTLIFDADV 75 Query: 70 TSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD----MPMADFRRAYELNVFSFFHL 125 + + D S+ ++D L+N AG P + + +F R Y +N+ + + Sbjct: 76 GKDADCRHAVDMVASRWQRIDALINCAGTTRVIPHNAFDQIDDFEFERVYRVNLIGLYQM 135 Query: 126 SQLVAPEMEKNGGG----VILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKN 181 ++ P + ++ ++ ++S+A N + +YA+SK A + L ++A +L Sbjct: 136 TRAAVPLLRESASATRSTSVVNVSSLAGLNGTGSSIAYAASKGAVNTLTLSLARNLAPH- 194 Query: 182 IRVNGIAPGAILTDALKSVIT----PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAAS 237 IRVN +APG + L V+ + +M + P++R+ +P +IA A FL + A Sbjct: 195 IRVNALAPGMVDDGLLLRVLDAAAYDGVLSRMTESAPLKRVSRPAEIAELAWFL-TAHAP 253 Query: 238 WVSGQILTVSGGGV 251 ++GQ++ G + Sbjct: 254 AITGQVIAAENGLL 267 >1E3W-A nrPDB Length = 261 Score = 174 bits (443), Expect = 2e-44, Method: Composition-based stats. Identities = 69/255 (27%), Positives = 116/255 (45%), Gaps = 20/255 (7%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 + G A+ITG +G+G A GA+ V+ D+ E ++LGG Sbjct: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGET---EAKKLGGNCIFAPA 63 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGP-KPFD------MPMADFRRAYELNVF 120 ++TSE+E+ A A K G++D+ VN AG K + + DF+R +N+ Sbjct: 64 NVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLI 123 Query: 121 SFFHLSQLVAPEMEKN------GGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMA 174 F++ +LVA M +N GVI+ S+AA + +Y++SK + +A Sbjct: 124 GTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183 Query: 175 FDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIR-RLGQPQDIANAALFLCS 233 DL IRV IAPG T L ++ + + P RLG P + A+ + Sbjct: 184 RDLAPIGIRVVTIAPGLFATPLLTTL-PDTVRNFLASQVPFPSRLGDPAEYAHLVQMVIE 242 Query: 234 PAASWVSGQILTVSG 248 +++G+++ + G Sbjct: 243 NP--FLNGEVIRLDG 255 >1P33-A nrPDB Length = 289 Score = 172 bits (437), Expect = 1e-43, Method: Composition-based stats. Identities = 59/278 (21%), Positives = 107/278 (38%), Gaps = 44/278 (15%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSD-INADAANHVVDEI-QQLGGQAFACRCDIT 70 A++TGA +G IA G +V + +A A+ + + + A + D++ Sbjct: 9 VALVTGAAKRLGSSIAEALHAEGYTVCLHYHRSAADASTLAATLNARRPNSAITVQADLS 68 Query: 71 SEQE-----------------LSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD--- 110 + SAL D G+ D+LVNNA P P A Sbjct: 69 NVATASFSETDGSVPVTLFSRCSALVDACYMHWGRCDVLVNNASSFYPTPLLRKDAGEGG 128 Query: 111 ------------FRRAYELNVFSFFHLSQLVAPEM------EKNGGGVILTITSMAAENK 152 + N + + L + A + ++ I+ + Sbjct: 129 SSVGDKESLEVAAADLFGSNAIAPYFLIKAFAQRVADTRAEQRGTSYSIVNMVDAMTSQP 188 Query: 153 NINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQH 212 + T Y +K A L R+ A +L IRVNG++PG L + +++ + Sbjct: 189 LLGYTMYTMAKEALEGLTRSAALELASLQIRVNGVSPGL---SVLPDDMPFSVQEDYRRK 245 Query: 213 TPI-RRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 P+ +R +++++ +FLCSP A +++G + V GG Sbjct: 246 VPLYQRNSSAEEVSDVVIFLCSPKAKYITGTCIKVDGG 283 >2QHX-A nrPDB Length = 328 Score = 172 bits (436), Expect = 2e-43, Method: Composition-based stats. Identities = 61/278 (21%), Positives = 104/278 (37%), Gaps = 44/278 (15%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSD-INADAANHVVDEI-QQLGGQAFACRCDIT 70 A++TGA +G+ IA G +V + +A AN + + + A + D++ Sbjct: 48 VALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLS 107 Query: 71 SEQE-----------------LSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD--- 110 + + L + G+ D+LVNNA P P D Sbjct: 108 NVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHE 167 Query: 111 ----FRRAYEL--------NVFSFFHLSQLVA------PEMEKNGGGVILTITSMAAENK 152 R A E N + + L + A P + I+ + Sbjct: 168 PCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQP 227 Query: 153 NINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQH 212 + T Y +K A L R+ A +L IRVNG+ PG L + P + + Sbjct: 228 LLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL---SVLVDDMPPAVWEGHRSK 284 Query: 213 TPI-RRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 P+ +R ++++ +FLCS A +++G + V GG Sbjct: 285 VPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGG 322 >2BFA-A nrPDB Length = 288 Score = 171 bits (435), Expect = 2e-43, Method: Composition-based stats. Identities = 61/278 (21%), Positives = 104/278 (37%), Gaps = 44/278 (15%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSD-INADAANHVVDEI-QQLGGQAFACRCDIT 70 A++TGA +G+ IA G +V + +A AN + + + A + D++ Sbjct: 8 VALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLS 67 Query: 71 SEQE-----------------LSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD--- 110 + + L + G+ D+LVNNA P P D Sbjct: 68 NVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHE 127 Query: 111 ----FRRAYEL--------NVFSFFHLSQLVA------PEMEKNGGGVILTITSMAAENK 152 R A E N + + L + A P + I+ + Sbjct: 128 PCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQP 187 Query: 153 NINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQH 212 + T Y +K A L R+ A +L IRVNG+ PG L + P + + Sbjct: 188 LLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL---SVLVDDMPPAVWEGHRSK 244 Query: 213 TPI-RRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 P+ +R ++++ +FLCS A +++G + V GG Sbjct: 245 VPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGG 282 >3RKU-A nrPDB Length = 287 Score = 166 bits (420), Expect = 1e-41, Method: Composition-based stats. Identities = 56/236 (23%), Positives = 101/236 (42%), Gaps = 14/236 (5%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAG---ASVVVSDINADAANHVVDEIQQ--LGGQA 62 RL K +ITGA AGIGK A+ + A ++++ + + I Q + Sbjct: 30 RLAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPNAKV 89 Query: 63 FACRCDITSEQELSALADFAISKLGKVDILVNNAG--GGGPKPFDMPMADFRRAYELNVF 120 + DIT +++ + + +DILVNNAG G + + D + ++ NV Sbjct: 90 HVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQIATEDIQDVFDTNVT 149 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 + +++Q V P + G I+ + S+A + + Y +SK A ++ +L Sbjct: 150 ALINITQAVLPIFQAKNSGDIVNLGSIAGRDAYPTGSIYCASKFAVGAFTDSLRKELINT 209 Query: 181 NIRVNGIAPGAILTDAL---KSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCS 233 IRV IAPG + T+ + + TP+ D+A+ ++ S Sbjct: 210 KIRVILIAPGLVETEFSLVRYRGNEEQAKNVYKDTTPL----MADDVADLIVYATS 261 >2NWQ-A nrPDB Length = 272 Score = 160 bits (406), Expect = 5e-40, Method: Composition-based stats. Identities = 52/228 (22%), Positives = 92/228 (40%), Gaps = 11/228 (4%) Query: 15 IITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQE 74 ITGA +G G+ A FA AG S+V++ + + E+ + D+ Sbjct: 25 FITGATSGFGEACARRFAEAGWSLVLTGRREERLQALAGELSAK-TRVLPLTLDVRDRAA 83 Query: 75 LSALADFAISKLGKVDILVNNAGGG-GPKPFD-MPMADFRRAYELNVFSFFHLSQLVAPE 132 +SA D + + L+NNAG G P + D+ + N+ + ++L+ P Sbjct: 84 MSAAVDNLPEEFATLRGLINNAGLALGTDPAQSCDLDDWDTMVDTNIKGLLYSTRLLLPR 143 Query: 133 MEKNG-GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPGA 191 + +G G I+ + S+A + Y +KA N+ DL +RV + PG Sbjct: 144 LIAHGAGASIVNLGSVAGKWPYPGSHVYGGTKAFVEQFSLNLRCDLQGTGVRVTNLEPGL 203 Query: 192 ILTDAL---KSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAA 236 ++ ++ PI QP+DIA ++ + A Sbjct: 204 CESEFSLVRFGGDQARYDKTYAGAHPI----QPEDIAETIFWIMNQPA 247 >3PPI-A nrPDB Length = 281 Score = 160 bits (405), Expect = 6e-40, Method: Composition-based stats. Identities = 68/255 (26%), Positives = 119/255 (46%), Gaps = 21/255 (8%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 + +G AI++G G+G+ G VV++D+ A+ + DE+ G +A Sbjct: 27 QFEGASAIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADEL---GNRAEFVST 83 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD-------FRRAYELNVF 120 ++TSE + A + A ++LG++ V GG G + F + +L + Sbjct: 84 NVTSEDSVLAAIEAA-NQLGRLRYAVVAHGGFGVAQRIVQRDGSPADMGGFTKTIDLYLN 142 Query: 121 SFFHLSQ------LVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMA 174 +++++ A E G ++ S+A I T+YA++KA L A Sbjct: 143 GTYNVARLVAASIAAAEPRENGERGALVLTASIAGYEGQIGQTAYAAAKAGVIGLTIAAA 202 Query: 175 FDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPI-RRLGQPQDIANAALFLCS 233 DL IRVN IAPG + T ++SV E K + P +RLG P + A+AA FL + Sbjct: 203 RDLSSAGIRVNTIAPGTMKTPIMESV-GEEALAKFAANIPFPKRLGTPDEFADAAAFLLT 261 Query: 234 PAASWVSGQILTVSG 248 +++G+++ + G Sbjct: 262 N--GYINGEVMRLDG 274 >5ILO-A nrPDB Length = 271 Score = 151 bits (382), Expect = 3e-37, Method: Composition-based stats. Identities = 46/212 (21%), Positives = 87/212 (41%), Gaps = 13/212 (6%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGA-SVVVSDINADAANHVVDEIQQLGGQAFACR 66 GK A++TG GIG +++ AGA V + D+ + V + Sbjct: 12 SFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIK 71 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLS 126 D+ +++ + A + G +DI+VN AG K D +R +N+ + + Sbjct: 72 MDVANKKGVEATYEEIAKTFGNIDIVVNVAGIFNDK-------DVQRTLLVNLGGIINST 124 Query: 127 QLVAPEMEKNG---GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFD--LGEKN 181 P M K+ GG+++ ++S+ + + Y ++KA + R +A + Sbjct: 125 LSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRSG 184 Query: 182 IRVNGIAPGAILTDALKSVITPEIEQKMLQHT 213 I+ + PGA +TD + I + T Sbjct: 185 IKFVTVCPGATMTDMFTNFTEKIIFPETSDET 216 >2HRB-A nrPDB Length = 274 Score = 148 bits (374), Expect = 2e-36, Method: Composition-based stats. Identities = 55/235 (23%), Positives = 85/235 (36%), Gaps = 55/235 (23%) Query: 12 KCAIITGAGAGIGKEIAITFATA-GASVVVSDINADAANHVVDEIQQLGGQAFACRCDIT 70 + A++TGA GIG IA VV++ + V ++Q G + DI Sbjct: 3 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDID 62 Query: 71 SEQELSALADFAISKLGKVDILVNNAGGG----GPKPFDMPMADFRRAYELNVFSFFHLS 126 Q + AL DF + G +++LVNNA P PFD+ + N F+ ++ Sbjct: 63 DLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAE---MTLKTNFFATRNMC 119 Query: 127 QLVAPEMEKNGGGVILTITSMAAENKNIN------------------------------- 155 + P M+ + G ++ I+S+ N Sbjct: 120 NELLPIMKPH--GRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTK 177 Query: 156 ----------MTSYASSKAAASHLVRNMAFDLGEK----NIRVNGIAPGAILTDA 196 + Y SK + L R +A L EK I VN PG + TD Sbjct: 178 NEVHEREGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDM 232 >4DRY-A nrPDB Length = 281 Score = 145 bits (367), Expect = 2e-35, Method: Composition-based stats. Identities = 59/233 (25%), Positives = 100/233 (42%), Gaps = 15/233 (6%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEI-QQLGGQAFACRCD 68 +G+ A++TG G G+G+ IA + G SVV++ D + EI + G A CD Sbjct: 32 EGRIALVTGGGTGVGRGIAQALSAEGYSVVITGRRPDVLDAAAGEIGGRTGNIVRAVVCD 91 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAGGGGP--KPFDMPMADFRRAYELNVFSFFHLS 126 + +++AL ++ ++D+LVNNAG P ++ + N+ F + Sbjct: 92 VGDPDQVAALFAAVRAEFARLDLLVNNAGSNVPPVPLEEVTFEQWNGIVAANLTGAFLCT 151 Query: 127 QLVAPEMEKN--GGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRV 184 Q M+ GG I+ S++A+ N Y ++K A + L ++ A D +I Sbjct: 152 QHAFRMMKAQTPRGGRIINNGSISAQTPRPNSAPYTATKHAITGLTKSTALDGRMHDIAC 211 Query: 185 NGIAPGAILTDAL----KSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCS 233 I G TD V+ E PI + IA A +++ S Sbjct: 212 GQIDIGNAATDMTARMSTGVLQANGEVAAEPTIPI------EHIAEAVVYMAS 258 >4Q9N-A nrPDB Length = 298 Score = 143 bits (362), Expect = 6e-35, Method: Composition-based stats. Identities = 61/285 (21%), Positives = 105/285 (36%), Gaps = 42/285 (14%) Query: 6 NLRLDGKCAIITGAG--AGIGKEIAITFATAGASVV---------VSDINADAANHVVDE 54 + L GK A I G G G G IA A AGA+++ + + + Sbjct: 3 KIDLTGKIAFIAGIGDDNGYGWGIAKMLAEAGATILVGTWVPIYKIFSQSLELGKFNASR 62 Query: 55 IQQLGG---QAFACRCDITSEQ--------------------ELSALADFAISKLGKVDI 91 G A D + + +S + + G +DI Sbjct: 63 ELSNGELLTFAKIYPMDASFDTPEDIPQEILENKRYKDLSGYTVSEVVEQVKKHFGHIDI 122 Query: 92 LVN---NAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLVAPEMEKNGGGVILTITSMA 148 LV+ N+ D + A + +SF L P M N G +++T +A Sbjct: 123 LVHSLANSPEIAKPLLDTSRKGYLAALSTSSYSFISLLSHFGPIM--NAGASTISLTYLA 180 Query: 149 AENKNINM-TSYASSKAAASHLVRNMAFDLGEK-NIRVNGIAPGAILTDALKSV-ITPEI 205 + ++KAA + +A++ G + +RVN I+ G + + A K++ + Sbjct: 181 SMRAVPGYGGGMNAAKAALESDTKVLAWEAGRRWGVRVNTISAGPLASRAGKAIGFIERM 240 Query: 206 EQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGGG 250 P+ + + + AA FL SP AS ++G+ L V G Sbjct: 241 VDYYQDWAPLPSPMEAEQVGAAAAFLVSPLASAITGETLYVDHGA 285 >1ENP-A nrPDB Length = 312 Score = 143 bits (361), Expect = 7e-35, Method: Composition-based stats. Identities = 70/283 (24%), Positives = 115/283 (40%), Gaps = 42/283 (14%) Query: 7 LRLDGKCAIITGAG--AGIGKEIAITFATAGASVVVS------------------DINAD 46 + L GK A I G G G +A + A AGA ++V D + Sbjct: 14 IDLRGKRAFIAGIADDNGYGWAVAKSLAAAGAEILVGTWVPALNIFETSLRRGKFDQSRV 73 Query: 47 AANHVVDEIQQLG------GQAFACRCDI--------TSEQELSALADFAISKLGKVDIL 92 + + EI+++ D+ +S + A+ G +DIL Sbjct: 74 LPDGSLMEIKKVYPLDAVFDNPEDVPEDVKANKRYAGSSNWTVQEAAECVRQDFGSIDIL 133 Query: 93 VN---NAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAA 149 V+ N + + A + +SF L P M N GG +++T +A+ Sbjct: 134 VHSLANGPEVSKPLLETSRKGYLAAISASSYSFVSLLSHFLPIM--NPGGASISLTYIAS 191 Query: 150 ENKNINM-TSYASSKAAASHLVRNMAFDLGEK-NIRVNGIAPGAILTDALKSV-ITPEIE 206 E +S+KAA R +AF+ G K NIRVN I+ G + + A K++ + Sbjct: 192 ERIIPGYGGGMSSAKAALESDTRVLAFEAGRKQNIRVNTISAGPLGSRAAKAIGFIDTMI 251 Query: 207 QKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 + + PI++ ++ NAA FL SP AS ++G + V G Sbjct: 252 EYSYNNAPIQKTLTADEVGNAAAFLVSPLASAITGATIYVDNG 294 >2O2S-A nrPDB Length = 315 Score = 141 bits (357), Expect = 2e-34, Method: Composition-based stats. Identities = 70/289 (24%), Positives = 109/289 (37%), Gaps = 48/289 (16%) Query: 7 LRLDGKCAIITGA--GAGIGKEIAITFATAGASVVVS------------------DINAD 46 + L G+ A + G G G IA A+AGA V + D + Sbjct: 5 IDLRGQTAFVAGVADSHGYGWAIAKHLASAGARVALGTWPPVLGLFQKSLQSGRLDEDRK 64 Query: 47 AANHVVDE------IQQLGGQAFACRCDITSEQ--------ELSALADFAISKLGKVDIL 92 + + E + + DI + + +A LG +DIL Sbjct: 65 LPDGSLIEFAGVYPLDAAFDKPEDVPQDIKDNKRYAGVDGYTIKEVAVKVKQDLGNIDIL 124 Query: 93 VNNAGGGGPK---PFDMPMADFRRAYELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAA 149 V++ G + + A + +SF L Q P M N GG +T++ +AA Sbjct: 125 VHSLANGPEVTKPLLETSRKGYLAASSNSAYSFVSLLQHFGPIM--NEGGSAVTLSYLAA 182 Query: 150 ENKNINMTS-YASSKAAASHLVRNMAFDLG-EKNIRVNGIAPGAILTDALKSVIT----- 202 E +S+KAA R +A++ G + +RVN I+ G + + A ++ Sbjct: 183 ERVVPGYGGGMSSAKAALESDTRTLAWEAGQKYGVRVNAISAGPLKSRAASAIGKSGEKS 242 Query: 203 --PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 + P+RR D+ AALFL SP A VSG L V G Sbjct: 243 FIDYAIDYSYNNAPLRRDLHSDDVGGAALFLLSPLARAVSGVTLYVDNG 291 >5PGZ-A nrPDB Length = 276 Score = 140 bits (353), Expect = 7e-34, Method: Composition-based stats. Identities = 50/191 (26%), Positives = 80/191 (41%), Gaps = 5/191 (2%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLG-GQAFACRC 67 L GK I+TGA GIG+E+A + GA VV++ + + VV +LG A Sbjct: 16 LQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHYIAG 75 Query: 68 DITSEQELSALADFAISKLGKVDILV-NNAGGGGPKPFDMPMADFRRAYELNVFSFFHLS 126 + A +G +D+L+ N+ F + RR E+N S+ +S Sbjct: 76 TMEDMTFAEQFIVKAGKLMGGLDMLILNHITQTSLSLFHDDIHSVRRVMEVNFLSYVVMS 135 Query: 127 QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNG 186 P M K G I I+S+A + + Y++SK A + +L + V+ Sbjct: 136 TAALP-MLKQSNGSIAVISSLAGKMTQPMIAPYSASKFALDGFFSTIRTELYITKVNVSI 194 Query: 187 --IAPGAILTD 195 G I T+ Sbjct: 195 TLCVLGLIDTE 205 >3DWF-A nrPDB Length = 276 Score = 139 bits (351), Expect = 1e-33, Method: Composition-based stats. Identities = 53/219 (24%), Positives = 90/219 (41%), Gaps = 10/219 (4%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLG-GQAFACRC 67 L GK I+TGA GIG+EIA A GA VVV+ + +A VV +LG A Sbjct: 9 LQGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASAHYIAG 68 Query: 68 DITSEQELSALADFAISKLGKVDILV-NNAGGGGPKPFDMPMADFRRAYELNVFSFFHLS 126 + A + +G +D+L+ N+ F + + R++ E+N SF LS Sbjct: 69 SMEDMTFAEEFVAEAGNLMGGLDMLILNHVLYNRLTFFHGEIDNVRKSMEVNFHSFVVLS 128 Query: 127 QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNG 186 P + ++ G I ++S+A + + Y++SK A + + + V+ Sbjct: 129 VAAMPMLMQSQ-GSIAVVSSVAGKITYPLIAPYSASKFALDGFFSTLRSEFLVNKVNVSI 187 Query: 187 IAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIA 225 T + +I E K + ++ A Sbjct: 188 -------TLCILGLIDTETAIKATSGIYLGPASPKEECA 219 >3UCF-A nrPDB Length = 223 Score = 138 bits (348), Expect = 2e-33, Method: Composition-based stats. Identities = 57/251 (22%), Positives = 102/251 (40%), Gaps = 35/251 (13%) Query: 6 NLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFAC 65 + D ++ G +GIG E+A + V V+ Sbjct: 1 MMGSDKTVYVVLGGTSGIGAELAKQLESEHTIVHVASRQ--------------------T 40 Query: 66 RCDITSEQELSALADFAISKLGKVDILVNNAGGGGP--KPFDMPMADFRRAYELNVFSFF 123 DI+ E+ + + G D L+ AG P K D+ + + A++ + Sbjct: 41 GLDISDEKSVYHYFETI----GAFDHLIVTAGSYAPAGKVVDVEVTQAKYAFDTKFWGAV 96 Query: 124 HLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIR 183 ++ A +++ GG I + M + N A+ AA + +A +L IR Sbjct: 97 LAAKHGARYLKQ--GGSITLTSGMLSRKVVANTYVKAAINAAIEATTKVLAKELAP--IR 152 Query: 184 VNGIAPGAILTDALKSVITPE---IEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVS 240 VN I+PG T+A K + + + Q+ H P+ ++G+ DIA A LF S+++ Sbjct: 153 VNAISPGLTKTEAYKGMNADDRDAMYQRTQSHLPVGKVGEASDIAMAYLFAIQN--SYMT 210 Query: 241 GQILTVSGGGV 251 G ++ V GG + Sbjct: 211 GTVIDVDGGAL 221 >3KZV-A nrPDB Length = 254 Score = 136 bits (343), Expect = 1e-32, Method: Composition-based stats. Identities = 56/189 (29%), Positives = 95/189 (50%), Gaps = 8/189 (4%) Query: 11 GKCAIITGAGAGIGKEIA-ITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDI 69 GK ++TG GIGK I + F+ +VV ++A + E + G + F DI Sbjct: 2 GKVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARSEAPLKKLKE--KYGDRFFYVVGDI 59 Query: 70 TSEQELSALADFAISKLGKVDILVNNAGGGGP--KPFDMPMADFRRAYELNVFSFFHLSQ 127 T + L L + A+ GK+D LV NAG P ++ + +++ Y++N FS L Sbjct: 60 TEDSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNEIDVNAWKKLYDINFFSIVSLVG 119 Query: 128 LVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGI 187 + PE++K G ++ ++S A + +Y SSKAA +H +A + E+ ++ + Sbjct: 120 IALPELKKTN-GNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANE--ERQVKAIAV 176 Query: 188 APGAILTDA 196 APG + TD Sbjct: 177 APGIVDTDM 185 >1A27-A nrPDB Length = 289 Score = 134 bits (339), Expect = 3e-32, Method: Composition-based stats. Identities = 47/219 (21%), Positives = 86/219 (39%), Gaps = 26/219 (11%) Query: 13 CAIITGAGAGIGKEIAITFATA---GASVVVSDINADAANHVVDEIQQLG---GQAFACR 66 +ITG +GIG +A+ A+ V + + + + + L G + Sbjct: 4 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 63 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD-FRRAYELNVFSFFHL 125 D+ + ++A + G+VD+LV NAG G P + D ++NV + Sbjct: 64 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 121 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 Q P+M++ G G +L S+ Y +SK A L ++A L + ++ Sbjct: 122 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLS 181 Query: 186 GIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDI 224 I G + T ++ V LG P+++ Sbjct: 182 LIECGPVHTAFMEKV-----------------LGSPEEV 203 >1N5D-A nrPDB Length = 288 Score = 134 bits (337), Expect = 4e-32, Method: Composition-based stats. Identities = 48/235 (20%), Positives = 78/235 (33%), Gaps = 55/235 (23%) Query: 12 KCAIITGAGAGIGKEIAITFATAGA-SVVVSDINADAANHVVDEIQQLGGQAFACRCDIT 70 + A++TGA GIG I A VV++ + V ++Q G + DI Sbjct: 5 RVALVTGANKGIGFAIVRDLCRQFAGDVVLTARDVARGQAAVKQLQAEGLSPRFHQLDII 64 Query: 71 SEQELSALADFAISKLGKVDILVNNAGGG----GPKPFDMPMADFRRAYELNVFSFFHLS 126 Q + AL DF + G +D+LVNNA P PF + + N ++ Sbjct: 65 DLQSIRALCDFLRKEYGGLDVLVNNAAIAFQLDNPTPFHIQAE---LTMKTNFMGTRNVC 121 Query: 127 QLVAPEMEKNGGGVILTITSMAAENK---------------------------------- 152 + P ++ G ++ ++S Sbjct: 122 TELLPLIKPQ--GRVVNVSSTEGVRALNECSPELQQKFKSETITEEELVGLMNKFVEDTK 179 Query: 153 -------NINMTSYASSKAAASHLVRNMAFDL----GEKNIRVNGIAPGAILTDA 196 + ++Y +K S L R A L I +N PG + TD Sbjct: 180 NGVHRKEGWSDSTYGVTKIGVSVLSRIYARKLREQRAGDKILLNACCPGWVRTDM 234 >6CGE-A nrPDB Length = 328 Score = 134 bits (337), Expect = 5e-32, Method: Composition-based stats. Identities = 47/219 (21%), Positives = 86/219 (39%), Gaps = 26/219 (11%) Query: 13 CAIITGAGAGIGKEIAITFATA---GASVVVSDINADAANHVVDEIQQLG---GQAFACR 66 +ITG +GIG +A+ A+ V + + + + + L G + Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD-FRRAYELNVFSFFHL 125 D+ + ++A + G+VD+LV NAG G P + D ++NV + Sbjct: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 Q P+M++ G G +L S+ Y +SK A L ++A L + ++ Sbjct: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLS 182 Query: 186 GIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDI 224 I G + T ++ V LG P+++ Sbjct: 183 LIECGPVHTAFMEKV-----------------LGSPEEV 204 >3E9N-A nrPDB Length = 245 Score = 133 bits (334), Expect = 1e-31, Method: Composition-based stats. Identities = 57/242 (23%), Positives = 96/242 (39%), Gaps = 17/242 (7%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 + L K A++TGA G+G EI + V N + + EI+ + Sbjct: 1 MSLKKKIAVVTGATGGMGIEIVKDLSRD-HIVYALGRNPEHLAALA-EIEGVEPIESDIV 58 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDM-PMADFRRAYELNVFSFFHL 125 ++ E + L L VD LV+ A + +A++ +LNV L Sbjct: 59 KEVLEEGGVDKL-----KNLDHVDTLVHAAAVARDTTIEAGSVAEWHAHLDLNVIVPAEL 113 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 S+ + P + G ++ I S A + T YA+SK A L + IRV+ Sbjct: 114 SRQLLPALRAA-SGCVIYINSGAGNGPHPGNTIYAASKHALRGLADAFRKEEANNGIRVS 172 Query: 186 GIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILT 245 ++PG T L+ ++ + + +P++IANA F+ A + QI Sbjct: 173 TVSPGPTNTPMLQGLMDSQGTNFRPEI-----YIEPKEIANAIRFVI--DAGETT-QITN 224 Query: 246 VS 247 V Sbjct: 225 VD 226 >3BHI-A nrPDB Length = 276 Score = 133 bits (334), Expect = 1e-31, Method: Composition-based stats. Identities = 56/282 (19%), Positives = 93/282 (32%), Gaps = 73/282 (25%) Query: 13 CAIITGAGAGIGKEIAITFATA-GASVVVSDINADAANHVVDEIQQLGGQAFACRCDITS 71 A++TG GIG I VV++ + V ++Q G + DI Sbjct: 6 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDD 65 Query: 72 EQELSALADFAISKLGKVDILVNNAGG----GGPKPFDMPMADFRRAYELNVFSFFHLSQ 127 Q + AL DF + G +D+LVNNAG P PF + + N F + Sbjct: 66 LQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAE---VTMKTNFFGTRDVCT 122 Query: 128 LVAPEMEKNGGGVILTITSMAAENK----------------------------------- 152 + P ++ G ++ ++S+ + Sbjct: 123 ELLPLIKPQ--GRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKK 180 Query: 153 ------NINMTSYASSKAAASHLVRNMAFDLGEK----NIRVNGIAPGAILTDALKSVIT 202 ++Y +K + L R A L E+ I +N PG + TD Sbjct: 181 GVHQKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMA----G 236 Query: 203 PEIEQKMLQHTPIRRLGQPQDIANAALFLC--SPAASWVSGQ 242 P+ + P++ A ++L P A GQ Sbjct: 237 PKATK------------SPEEGAETPVYLALLPPDAEGPHGQ 266 >2NTV-A nrPDB Length = 268 Score = 129 bits (324), Expect = 2e-30, Method: Composition-based stats. Identities = 61/269 (22%), Positives = 114/269 (42%), Gaps = 28/269 (10%) Query: 9 LDGKCAIITG--AGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 L+GK +++G + I IA AGA +V++ D + +L +A Sbjct: 4 LEGKRILVSGIITDSSIAFHIAKVAQEAGAQLVLTGF--DRLRLIQRIADRLPDKAPLIE 61 Query: 67 CDITSEQELSALADFAISKLG---KVDILVNNAGG------GGPKPFDMPMADFRRAYEL 117 D+ +E+ L+ LA+ +++G K+D +V++ G G + FD P D + + Sbjct: 62 LDVQNEEHLATLAERVTAEIGEGNKLDGVVHSIGFMPQTGMGTNQFFDAPYEDVSKGIHI 121 Query: 118 NVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDL 177 + +S+ L++ + M N GG I+ + +K+A + R +A + Sbjct: 122 STYSYASLAKALLLIM--NSGGSIVGMD-FDPTRAMPAYNWMTVAKSALESVNRFVAREA 178 Query: 178 GEKNIRVNGIAPGAILTDALKSVIT-----------PEIEQKMLQHTPIRR-LGQPQDIA 225 G+ +R N +A G I T A+ +++ +E+ Q PI + P +A Sbjct: 179 GKYGVRSNLVAAGPIRTLAMSAIVGGAFGEEAGAQMQLLEEGWDQRAPIGWNMKDPTPVA 238 Query: 226 NAALFLCSPAASWVSGQILTVSGGGVQEL 254 L S +G I+ GG +L Sbjct: 239 KTVCALLSEWLPATTGSIIYADGGASTQL 267 >3U9L-A nrPDB Length = 324 Score = 126 bits (316), Expect = 1e-29, Method: Composition-based stats. Identities = 56/242 (23%), Positives = 96/242 (39%), Gaps = 13/242 (5%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVV-----VSDINADAANHVVDEIQQLGGQ 61 + + K +ITGA +G G+ A A AG V + NA + + Sbjct: 1 MVMSKKIILITGASSGFGRLTAEALAGAGHRVYASMRDIVGRNASNVEAIAGFARDNDVD 60 Query: 62 AFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVF 120 D+ S+ + D I + G++D+L++NAG P + F Y++NV Sbjct: 61 LRTLELDVQSQVSVDRAIDQIIGEDGRIDVLIHNAGHMVFGPAEAFTPEQFAELYDINVL 120 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINM-TSYASSKAAASHLVRNMAFDLGE 179 S +++ P M + G+++ I+S ++ Y ++KAA + A +L Sbjct: 121 STQRVNRAALPHMRRQKHGLLIWISSSSSAGGTPPYLAPYFAAKAAMDAIAVQYARELSR 180 Query: 180 KNIRVNGIAPGAILTD----ALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPA 235 I + I PGA + A V Q + P LG ++I A + P Sbjct: 181 WGIETSIIVPGAFTSGTNHFAHSGVPDDHARQAEYEAGPNAGLG--EEIKKAFAAIVPPD 238 Query: 236 AS 237 A Sbjct: 239 AD 240 >4OYR-A nrPDB Length = 289 Score = 125 bits (315), Expect = 1e-29, Method: Composition-based stats. Identities = 60/269 (22%), Positives = 110/269 (40%), Gaps = 28/269 (10%) Query: 9 LDGKCAIITG--AGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 LDGK +++G + I IA GA +V++ D + +L +A Sbjct: 25 LDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGF--DRLRLIQRITDRLPAKAPLLE 82 Query: 67 CDITSEQELSALADFAISKLG---KVDILVNNAGGGGPK------PFDMPMADFRRAYEL 117 D+ +E+ L++LA +G K+D +V++ G FD P AD + + Sbjct: 83 LDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHI 142 Query: 118 NVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDL 177 + +S+ +++ + P M N GG I+ + +K+A + R +A + Sbjct: 143 SAYSYASMAKALLPIM--NPGGSIVGMD-FDPSRAMPAYNWMTVAKSALESVNRFVAREA 199 Query: 178 GEKNIRVNGIAPGAILTDALKSVIT-----------PEIEQKMLQHTPIRR-LGQPQDIA 225 G+ +R N +A G I T A+ +++ +E+ Q PI + +A Sbjct: 200 GKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVA 259 Query: 226 NAALFLCSPAASWVSGQILTVSGGGVQEL 254 L S +G I+ GG +L Sbjct: 260 KTVCALLSDWLPATTGDIIYADGGAHTQL 288 >2PTG-A nrPDB Length = 319 Score = 124 bits (313), Expect = 3e-29, Method: Composition-based stats. Identities = 66/300 (22%), Positives = 112/300 (37%), Gaps = 61/300 (20%) Query: 9 LDGKCAIITGA--GAGIGKEIAITFATAGASVVV----------------------SDIN 44 L GK A + G G G I AGA V+V S Sbjct: 7 LRGKTAFVAGVADSNGYGWAICKLLRAAGARVLVGTWPPVYSIFKKGLESSRFEQDSFYA 66 Query: 45 ADAANHVVDEIQQLGGQAFA---------------CRCDITSEQ--------ELSALADF 81 + ++ V E + +++S + +S +A+ Sbjct: 67 QEPSSKVAAEAAEKPVDLVFDKIYPLDAVFDTPQDVPPEVSSNKRYAGVGGFTISEVAEA 126 Query: 82 AISKLGKVDILVNNAGGGGPK---PFDMPMADFRRAYELNVFSFFHLSQLVAPEMEKNGG 138 + +G++DILV++ G + A + +SF L Q P M++ G Sbjct: 127 VRADVGQIDILVHSLANGPEVTKPLLQTSRKGYLAAVSSSSYSFVSLLQHFLPLMKE--G 184 Query: 139 GVILTITSMAAENKNINMTS-YASSKAAASHLVRNMAFDLGE-KNIRVNGIAPGAILTDA 196 G L ++ +A+E +S+KAA R +AF+ G + +RVN I+ G + + A Sbjct: 185 GSALALSYIASEKVIPGYGGGMSSAKAALESDCRTLAFEAGRARAVRVNCISAGPLKSRA 244 Query: 197 LKSVIT-------PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 ++ + P+++ + D+ AALFL SP A V+G L V G Sbjct: 245 ASAIGKAGDKTFIDLAIDYSEANAPLQKELESDDVGRAALFLLSPLARAVTGATLYVDNG 304 >2DKN-A nrPDB Length = 255 Score = 123 bits (309), Expect = 8e-29, Method: Composition-based stats. Identities = 60/267 (22%), Positives = 98/267 (36%), Gaps = 52/267 (19%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSE 72 ITG+ +GIG + A AG +V+ D D+++ Sbjct: 3 VIAITGSASGIGAALKELLARAGHTVIGIDRGQAD-----------------IEADLSTP 45 Query: 73 QELSALADFAISKLGK-VDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLVAP 131 + + G +D LV AG G + A+ +N F L +A Sbjct: 46 GGRETAVAAVLDRCGGVLDGLVCCAGVG------VTAANSGLVVAVNYFGVSALLDGLAE 99 Query: 132 EMEKNGGGVILTITSMAAENKNI--------------------------NMTSYASSKAA 165 + + + + S+AA +YA SK A Sbjct: 100 ALSRGQQPAAVIVGSIAATQPGAAELPMVEAMLAGDEARAIELAEQQGQTHLAYAGSKYA 159 Query: 166 ASHLVRNMAFDLGEKNIRVNGIAPGAILTDALK-SVITPEIEQKMLQHT-PIRRLGQPQD 223 + L R D + +R+N +APGA+ T L+ S P + + P+ R +P++ Sbjct: 160 VTCLARRNVVDWAGRGVRLNVVAPGAVETPLLQASKADPRYGESTRRFVAPLGRGSEPRE 219 Query: 224 IANAALFLCSPAASWVSGQILTVSGGG 250 +A A FL P AS++ G +L V GG Sbjct: 220 VAEAIAFLLGPQASFIHGSVLFVDGGM 246 >4HBG-A nrPDB Length = 286 Score = 122 bits (308), Expect = 9e-29, Method: Composition-based stats. Identities = 57/273 (20%), Positives = 99/273 (36%), Gaps = 52/273 (19%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQL-------------- 58 AI+TGA GIGK I G S ++ ++ + QL Sbjct: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 Query: 59 GGQAFACRCDITSEQELSALADF--AISKLGKV----------------DILVNNAGGGG 100 + + D S + D K + ++L+N AG Sbjct: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 Query: 101 PKP-FDMPMADFRRAYELNVFSFFHLSQLVAPEMEKNGGG-----------VILTITSM- 147 + + +N S ++ + M K+ I+ I+S+ Sbjct: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 Query: 148 -AAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPGAIL-TDALKSVITPEI 205 + + K + Y++SKAA S +A ++ +NIR I+PG + TD ++++ P Sbjct: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL--PVE 243 Query: 206 EQKMLQHTPIRRLGQ--PQDIANAALFLCSPAA 236 ++ML+ T I G P +IA L S A Sbjct: 244 AKEMLERT-IGASGTSAPAEIAEEVWSLYSRTA 275 >5L51-A nrPDB Length = 324 Score = 122 bits (308), Expect = 1e-28, Method: Composition-based stats. Identities = 50/273 (18%), Positives = 95/273 (34%), Gaps = 85/273 (31%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGASVVVSDINA----DAANHVVDEI-QQLGGQAFA 64 + A++TGA GIG EI A+ G +V+++ + +A ++ E+ + G + Sbjct: 14 TKRYAVVTGANKGIGFEICKQLASKGITVILASRDEKRGIEARERLIKELGSEFGDYVVS 73 Query: 65 CRCDITSEQELSALADFAISKLGKVDILVNNAGGGG------------------------ 100 + D+ ++AL DF +K G +DILVNNAG G Sbjct: 74 QQLDVADPASVAALVDFIKTKFGSLDILVNNAGLNGTYMEGDASVLNDYVEAEFKTFQSG 133 Query: 101 ---PKPFD--------MPMADFRRAYELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAA 149 +P+ + + E N + +++ + P ++++ I+ ++S + Sbjct: 134 AAKTEPYHPKATGRLVETVEHAKECIETNYYGSKRVTEALIPLLQQSDSPRIVNVSSTLS 193 Query: 150 ENK-------------------------------------------NINMTSYASSKAAA 166 + ++Y SKAA Sbjct: 194 SLVFQTNEWAKGVFSSEEGLTEEKLEEVLAEFLKDFIDGKQQEKQWPPHFSAYKVSKAAL 253 Query: 167 SHLVRNMAFDLGEKNIRVNGIAPGAILTDALKS 199 + R +A R+N + PG TD Sbjct: 254 NAYTRIIAKKYPSF--RINAVCPGYTKTDLSYG 284 >3F4B-A nrPDB Length = 323 Score = 121 bits (303), Expect = 4e-28, Method: Composition-based stats. Identities = 56/294 (19%), Positives = 99/294 (33%), Gaps = 64/294 (21%) Query: 18 GAGAGIGKEIAITFATAGASVVVSDI---------NADAANHVVDEIQQLGGQAFACRCD 68 G G G IA + V+ N ++ D I D Sbjct: 16 GDSNGYGWGIAKELSKRNVKVIFGVWPPVYNIFIKNLESGKFDKDMIINNDNSKRMQILD 75 Query: 69 I------------TSEQ-------------ELSALADFAISKLGKVDILVNNAGGGG--- 100 + E + +A+ +K GK+ +LV++ G Sbjct: 76 VLPLDAGFDNYDDIDEDTKNNKRYNNLKNYSIEEVANLIYNKYGKISMLVHSLANGREVQ 135 Query: 101 PKPFDMPMADFRRAYELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTS-Y 159 D + A + +S L + M N GG ++++T A++ Sbjct: 136 KSLLDTSRDGYLDAISKSSYSLISLCKHFCKFM--NSGGSVVSLTYQASQKVVPGYGGGM 193 Query: 160 ASSKAAASHLVRNMAFDLGEK-NIRVNGIAPGAILTDALKSVIT---------------- 202 +S+KAA R +A+ LG K NIR+N I+ G + + A ++ Sbjct: 194 SSAKAALESDTRVLAYYLGRKYNIRINTISAGPLKSRAATAINKFNNNQKNNMNSSGETD 253 Query: 203 -------PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSGQILTVSGG 249 ++ P+++ D+ + A FL S +S V+GQ + V G Sbjct: 254 KQNYSFIDYAIDYSEKYAPLKKKLLSTDVGSVASFLLSKESSAVTGQTIYVDNG 307 >1FJH-A nrPDB Length = 257 Score = 116 bits (291), Expect = 1e-26, Method: Composition-based stats. Identities = 65/268 (24%), Positives = 100/268 (37%), Gaps = 54/268 (20%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSE 72 +I+G GIG AG +V DI D+++ Sbjct: 3 IIVISGCATGIGAATRKVLEAAGHQIVGIDIRDAE-----------------VIADLSTA 45 Query: 73 QELSALADFAISKLGK-VDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLVAP 131 + ++K K +D LV AG G +N F L P Sbjct: 46 EGRKQAIADVLAKCSKGMDGLVLCAGLGPQTKVLGN------VVSVNYFGATELMDAFLP 99 Query: 132 EMEKNGGGVILTITSMA----AENKNI------------------------NMTSYASSK 163 ++K + I+S+A A +KN +YA SK Sbjct: 100 ALKKGHQPAAVVISSVASAHLAFDKNPLALALEAGEEAKARAIVEHAGEQGGNLAYAGSK 159 Query: 164 AAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVI-TPEIEQKMLQHTP-IRRLGQP 221 A + VR A GE +R+N IAPGA T L++ + P + + + P + R +P Sbjct: 160 NALTVAVRKRAAAWGEAGVRLNTIAPGATETPLLQAGLQDPRYGESIAKFVPPMGRRAEP 219 Query: 222 QDIANAALFLCSPAASWVSGQILTVSGG 249 ++A+ FL SPAAS+V G + + GG Sbjct: 220 SEMASVIAFLMSPAASYVHGAQIVIDGG 247 >3O26-A nrPDB Length = 311 Score = 115 bits (288), Expect = 2e-26, Method: Composition-based stats. Identities = 56/307 (18%), Positives = 106/307 (34%), Gaps = 88/307 (28%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQ-AFACRCDIT 70 +CA++TG GIG EI ++ G VV++ + + V++++ + + D+T Sbjct: 13 RCAVVTGGNKGIGFEICKQLSSNGIMVVLTCRDVTKGHEAVEKLKNSNHENVVFHQLDVT 72 Query: 71 SE-QELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYE------------- 116 +S+LADF + GK+DILVNNAG G F + F+ Sbjct: 73 DPIATMSSLADFIKTHFGKLDILVNNAGVAG---FSVDADRFKAMISDIGEDSEELVKIY 129 Query: 117 ---------------------LNVFSFFHLSQLVAPEMEKNGGGVILTITSMAA------ 149 +N +++++ P ++ + I+ ++S Sbjct: 130 EKPEAQELMSETYELAEECLKINYNGVKSVTEVLIPLLQLSDSPRIVNVSSSTGSLKYVS 189 Query: 150 ------------------------------------ENKNINM-TSYASSKAAASHLVRN 172 N + +Y +SKA + R Sbjct: 190 NETALEILGDGDALTEERIDMVVNMLLKDFKENLIETNGWPSFGAAYTTSKACLNAYTRV 249 Query: 173 MAFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFL- 231 +A + + VN + PG + T+ + E+ I P D + F Sbjct: 250 LANKIPKFQ--VNCVCPGLVKTEMNYGIGNYTAEEGAEHVVRIALF--PDD-GPSGFFYD 304 Query: 232 CSPAASW 238 CS +++ Sbjct: 305 CSELSAF 311 >5LCX-A nrPDB Length = 316 Score = 111 bits (277), Expect = 4e-25, Method: Composition-based stats. Identities = 54/290 (18%), Positives = 92/290 (31%), Gaps = 89/290 (30%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINA----DAANHVVDEIQQLGGQAFACRC 67 + A++TGA GIG EI A G V+++ N +A ++ E+ + + Sbjct: 8 RYALVTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKELNVSENRLVFHQL 67 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-------DMPMADFRRAYE---- 116 D+T ++A+A F SK GK+DILVNNAG G + + ADF+ Sbjct: 68 DVTDLASVAAVAVFIKSKFGKLDILVNNAGVSGVEMVGDVSVFNEYIEADFKALQALEAG 127 Query: 117 ---------------------------LNVFSFFHLSQLVAPEMEKNGGGVILTI----- 144 N + L+Q + P ++ + I+ + Sbjct: 128 AKEEPPFKPKANGEMIEKFEGAKDCVVTNYYGPKRLTQALIPLLQLSPSPRIVNVSSSFG 187 Query: 145 --------------------------------------TSMAAENKNINMTSYASSKAAA 166 + + + SKAA Sbjct: 188 SLLLLWNEWAKGVLGDEDRLTEERVDEVVEVFLKDIKEGKLEESQWPPHFAAERVSKAAL 247 Query: 167 SHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIR 216 + + A R+N I PG TD + + P++ Sbjct: 248 NAYTKIAAKKYPSF--RINAICPGYAKTDITFHAGPLSVAE--AAQVPVK 293 >4Z3K-A nrPDB Length = 275 Score = 110 bits (275), Expect = 7e-25, Method: Composition-based stats. Identities = 52/239 (21%), Positives = 98/239 (41%), Gaps = 23/239 (9%) Query: 2 FNSDNLRLDGKCAIITGAGAGIGK---EIAITFATAGASVVVSDINADAANHVVDEI--Q 56 F L ++TGA G G+ + + + G+ +V+S N +A + E+ + Sbjct: 12 FQGMEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAE 71 Query: 57 QLGGQAFACRCDITSEQELSALADFAIS-----KLGKVDILVNNAGGGGP---KPFDMPM 108 + G + D+ +E L L L ++ +L+NNAG G D+ Sbjct: 72 RSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSD 130 Query: 109 A-DFRRAYELNVFSFFHLSQLVAPEMEKNGG--GVILTITSMAAENKNINMTSYASSKAA 165 + + LN+ S L+ V + G ++ I+S+ A Y + KAA Sbjct: 131 STQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAA 190 Query: 166 ASHLVRNMAFDLGEKNIRVNGIAPGAILTDALK----SVITPEIEQKMLQHTPIRRLGQ 220 L + +A + E N+RV APG + TD + + + P++ + + + +L Sbjct: 191 RDMLFQVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVD 247 >4HWK-A nrPDB Length = 288 Score = 109 bits (272), Expect = 2e-24, Method: Composition-based stats. Identities = 50/228 (21%), Positives = 96/228 (42%), Gaps = 23/228 (10%) Query: 13 CAIITGAGAGIGK---EIAITFATAGASVVVSDINADAANHVVDEI--QQLGGQAFACRC 67 ++TGA G G+ + + + G+ +V+S N +A + E+ ++ G + Sbjct: 36 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 95 Query: 68 DITSEQELSALADFAIS-----KLGKVDILVNNAGGGGP---KPFDMPMA-DFRRAYELN 118 D+ +E L L L ++ +L+NNAG G D+ + + LN Sbjct: 96 DLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 154 Query: 119 VFSFFHLSQLVAPEMEKNGG--GVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFD 176 + S L+ V + G ++ I+S+ A Y + KAA L + +A + Sbjct: 155 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 214 Query: 177 LGEKNIRVNGIAPGAILTDALK----SVITPEIEQKMLQHTPIRRLGQ 220 E N+RV APG + TD + + + P++ + + + +L Sbjct: 215 --EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVD 260 >2O2Y-A nrPDB Length = 349 Score = 107 bits (269), Expect = 3e-24, Method: Composition-based stats. Identities = 50/313 (15%), Positives = 98/313 (31%), Gaps = 83/313 (26%) Query: 18 GAGAGIGKEIAITFATAGASVVV------------SDINADAANHVVDEIQQLGGQAFAC 65 G G G IA + ++ + N N ++ + + Sbjct: 23 GDTNGYGWGIAKELSKRNVKIIFGIWPPVYNIFMKNYKNGKFDNDMIIDKDKKMNILDML 82 Query: 66 RCDITSEQE--------------------LSALADFAISKLGKVDILVN---NAGGGGPK 102 D + + + +A+ K GK+++LV+ NA Sbjct: 83 PFDASFDTANDIDEETKNNKRYNMLQNYTIEDVANLIHQKYGKINMLVHSLANAKEVQKD 142 Query: 103 PFDMPMADFRRAYELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTS-YAS 161 + + A + +S L + M+ I+++T A++ +S Sbjct: 143 LLNTSRKGYLDALSKSSYSLISLCKYFVNIMKPQ--SSIISLTYHASQKVVPGYGGGMSS 200 Query: 162 SKAAASHLVRNMAFDLGE-KNIRVNGIAPGAILTDALKSVIT------------------ 202 +KAA R +A+ LG NIR+N I+ G + + A ++ Sbjct: 201 AKAALESDTRVLAYHLGRNYNIRINTISAGPLKSRAATAINKLNNTYENNTNQNKNRNSH 260 Query: 203 --------------------------PEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAA 236 + ++ P+R+ DI + A FL S + Sbjct: 261 DVHNIMNNSGEKEEKKNSASQNYTFIDYAIEYSEKYAPLRQKLLSTDIGSVASFLLSRES 320 Query: 237 SWVSGQILTVSGG 249 ++GQ + V G Sbjct: 321 RAITGQTIYVDNG 333 >1SNY-A nrPDB Length = 267 Score = 106 bits (266), Expect = 8e-24, Method: Composition-based stats. Identities = 35/204 (17%), Positives = 75/204 (36%), Gaps = 22/204 (10%) Query: 14 AIITGAGAGIGKEIAITFA---TAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDIT 70 +ITG G+G + + + N + A + D + + D+ Sbjct: 24 ILITGCNRGLGLGLVKALLNLPQPPQHLFTTCRNREQAKELED-LAKNHSNIHILEIDLR 82 Query: 71 SEQELSALADFA--ISKLGKVDILVNNAGGGG--PKPFDMPMADFRRAYELNVFSFFHLS 126 + L ++K +++L NNAG + + + + N L+ Sbjct: 83 NFDAYDKLVADIEGVTKDQGLNVLFNNAGIAPKSARITAVRSQELLDTLQTNTVVPIMLA 142 Query: 127 QLVAPEMEKN-----------GGGVILTITSMAAENKN---INMTSYASSKAAASHLVRN 172 + P ++K G I+ ++S+ + M +Y +SK+A + ++ Sbjct: 143 KACLPLLKKAAKANESQPMGVGRAAIINMSSILGSIQGNTDGGMYAYRTSKSALNAATKS 202 Query: 173 MAFDLGEKNIRVNGIAPGAILTDA 196 ++ DL + I + PG + TD Sbjct: 203 LSVDLYPQRIMCVSLHPGWVKTDM 226 >1B15-A nrPDB Length = 254 Score = 101 bits (251), Expect = 4e-22, Method: Composition-based stats. Identities = 45/219 (20%), Positives = 78/219 (35%), Gaps = 23/219 (10%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGAS-VVVSDINADAANHVVDEIQQLGGQA--F 63 + L K I A GIG + + V+ D + + E++ + + Sbjct: 1 MDLTNKNVIFVAALGGIGLDTSRELVKRNLKNFVILDRVENP--TALAELKAINPKVNIT 58 Query: 64 ACRCDITSE-QELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSF 122 D+T E L +L VDIL+N AG + R +N Sbjct: 59 FHTYDVTVPVAESKKLLKKIFDQLKTVDILINGAGILDDHQIE-------RTIAINFTGL 111 Query: 123 FHLSQLVAPEMEKNGGG---VILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGE 179 + + + +K GG +I I S+ N + Y++SKAA ++A L Sbjct: 112 VNTTTAILDFWDKRKGGPGGIIANICSVTGFNAIHQVPVYSASKAAVVSFTNSLAK-LAP 170 Query: 180 -KNIRVNGIAPGAILTDALKSV-----ITPEIEQKMLQH 212 + I PG T + + + P + + +L H Sbjct: 171 ITGVTAYSINPGITRTPLVHTFNSWLDVEPRVAELLLSH 209 >1MG5-A nrPDB Length = 255 Score = 98.7 bits (245), Expect = 2e-21, Method: Composition-based stats. Identities = 42/218 (19%), Positives = 77/218 (35%), Gaps = 19/218 (8%) Query: 6 NLRLDGKCAIITGAGAGIGKEIAITFATAGAS-VVVSDINADAANHVVDEIQQLGGQAFA 64 + L K I GIG + + +V+ D + A + Sbjct: 1 SFTLTNKNVIFVAGLGGIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKVTVTF 60 Query: 65 CRCDITSE-QELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFF 123 D+T E + L ++L VD+L+N AG + R +N Sbjct: 61 YPYDVTVPIAETTKLLKTIFAQLKTVDVLINGAGILDDHQIE-------RTIAVNYTGLV 113 Query: 124 HLSQLVAPEMEKNGGG---VILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGE- 179 + + + +K GG +I I S+ N + Y+ +KAA + ++A L Sbjct: 114 NTTTAILDFWDKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAK-LAPI 172 Query: 180 KNIRVNGIAPGAILTDALKSV-----ITPEIEQKMLQH 212 + + PG T + + P++ +K+L H Sbjct: 173 TGVTAYTVNPGITRTTLVHKFNSWLDVEPQVAEKLLAH 210 >1OAA-A nrPDB Length = 259 Score = 97.2 bits (241), Expect = 6e-21, Method: Composition-based stats. Identities = 47/219 (21%), Positives = 89/219 (40%), Gaps = 23/219 (10%) Query: 13 CAIITGAGAGIGKEIAITFATA---GASVVVSDINADAANHVVDEI--QQLGGQAFACRC 67 ++TGA G G+ +A A G+ ++VS + + +E+ QQ + Sbjct: 8 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAA 67 Query: 68 DITSEQELSALADFAIS-----KLGKVDILVNNAGGGGPKPF-DMPMADFRRA---YELN 118 D+ +E + L L ++ +L+NNA G + + D + LN Sbjct: 68 DLGTEAGVQRLLSAVRELPRPEGLQRL-LLINNAATLGDVSKGFLNVNDLAEVNNYWALN 126 Query: 119 VFSFFHLSQLVAPEMEKNGGGV--ILTITSMAAENKNINMTSYASSKAAASHLVRNMAFD 176 + S L+ + + G ++ I+S+ A Y + KAA L + +A + Sbjct: 127 LTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAAE 186 Query: 177 LGEKNIRVNGIAPGAILTDALK----SVITPEIEQKMLQ 211 E ++RV APG + D + + PE+ K+ + Sbjct: 187 --EPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQK 223 >5WQO-A nrPDB Length = 234 Score = 94.9 bits (235), Expect = 3e-20, Method: Composition-based stats. Identities = 46/221 (20%), Positives = 85/221 (38%), Gaps = 15/221 (6%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSE 72 +I GA GIG +A F GA V + + ++ G + A D+ Sbjct: 8 NVLIVGASRGIGLGLADAFLQRGAQVFAVARRPQGSPGLQALAERAGERLQAVTGDLNQH 67 Query: 73 QELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRA---YELNVFSFFHLSQLV 129 + + + ++D L+ NAG GP+ D+ D + + N + L++ + Sbjct: 68 DCAERIGEMLGER--RIDRLIVNAGIYGPQQQDVAEIDAEQTAQLFLTNAIAPLRLARAL 125 Query: 130 APEMEKNGGGVILTITSMAAENK---NINMTSYASSKAAASHLVRNMAFDLGEKNIRVNG 186 + + GGV+ ++S A + M Y +SKAA + LVR+ + E + Sbjct: 126 SG--RVSRGGVVAFMSSQMASLALGLSATMPLYGASKAALNSLVRSWEGEFEELPFSLLL 183 Query: 187 IAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANA 227 + PG + T+ +E+ +D A Sbjct: 184 LHPGWVRTEMGGDSAPLSVEESAAGLVAA-----VEDAAGV 219 >5TQV-A nrPDB Length = 233 Score = 90.3 bits (223), Expect = 8e-19, Method: Composition-based stats. Identities = 43/191 (22%), Positives = 83/191 (43%), Gaps = 17/191 (8%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITS 71 K +I GA G+G+E + G +V+ + + + + ++ LG A A DIT Sbjct: 10 KTVLIVGASRGLGREFVRQYQRDGWNVIATARD----DASLAALRALGAHAHAL--DITQ 63 Query: 72 EQELSALADFAISKLGKVDILVNNAGGGGPKPFDMP---MADFRRAYELNVFSFFHLSQL 128 ++++AL + ++D+ V +G GP+ + DF NV L + Sbjct: 64 PEQIAALGWKLDGE--RLDVAVVVSGVYGPRTEGVETIASDDFDTVMHTNVRGPMQLLPI 121 Query: 129 VAPEMEKNGGGVILT---ITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 + P +E G + + + S++ Y +SKAA + ++R + L ++ Sbjct: 122 LLPLVEDARGVLAVVSSRMGSISEATGTTGW-LYRASKAALNDVLRIAS--LQTRHAACI 178 Query: 186 GIAPGAILTDA 196 + PG + TD Sbjct: 179 SLHPGWVRTDM 189 >3ORF-A nrPDB Length = 251 Score = 82.2 bits (202), Expect = 2e-16, Method: Composition-based stats. Identities = 46/213 (21%), Positives = 89/213 (41%), Gaps = 21/213 (9%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITS 71 K ++ G +G E+ F + + + D + I+ G Sbjct: 23 KNILVLGGSGALGAEVVKFFKSKSWNTISIDFRENPNADHSFTIKDSG------------ 70 Query: 72 EQELSALADFAISKLGKVDILVNNAGG--GGPKPFDMPMADFRRAYELNVFSFFHLSQLV 129 E+E+ ++ + SK KVD V AGG GG D + + ++N++S F + + Sbjct: 71 EEEIKSVIEKINSKSIKVDTFVCAAGGWSGGNASSDEFLKSVKGMIDMNLYSAFASAHIG 130 Query: 130 APEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLG--EKNIRVNGI 187 A + N GG+ + + AA N+ M +Y ++KAA H+++++A + G GI Sbjct: 131 AKLL--NQGGLFVLTGASAALNRTSGMIAYGATKAATHHIIKDLASENGGLPAGSTSLGI 188 Query: 188 APGAILTDALKSVITPEIEQKMLQHTPIRRLGQ 220 P + T + ++ TP+ + + Sbjct: 189 LPVTLDTPTNRKYMSD---ANFDDWTPLSEVAE 218 >3SLK-A nrPDB Length = 795 Score = 71.4 bits (174), Expect = 4e-13, Method: Composition-based stats. Identities = 28/186 (15%), Positives = 68/186 (36%), Gaps = 24/186 (12%) Query: 13 CAIITGAGAGIGKEIAITFA-TAGAS-VVVSDIN---ADAANHVVDEIQQLGGQAFACRC 67 ++TG +G E+A G +V+ A A +V ++ G + C Sbjct: 532 TVLVTGGTGALGAEVARHLVIERGVRNLVLVSRRGPAASGAAELVAQLTAYGAEVSLQAC 591 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRAYELNVFSFFHLS 126 D+ + L+ + + + +V+ AG + + + + V +L Sbjct: 592 DVADRETLAKVLASIPDEH-PLTAVVHAAGVLDDGVSESLTVERLDQVLRPKVDGARNLL 650 Query: 127 QLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHL----------VRNMAFD 176 +L+ P++ ++ +S++ + +YA++ + L R++A+ Sbjct: 651 ELIDPDV------ALVLFSSVSGVLGSGGQGNYAAANSFLDALAQQRQSRGLPTRSLAWG 704 Query: 177 -LGEKN 181 E Sbjct: 705 PWAEHG 710 >4LIS-A nrPDB Length = 371 Score = 65.6 bits (159), Expect = 2e-11, Method: Composition-based stats. Identities = 31/170 (18%), Positives = 57/170 (33%), Gaps = 27/170 (15%) Query: 14 AIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQ-LGGQAFACRCDITSE 72 ++TG IG + AG VVV+D +++ ++ I+ G +A + D+T E Sbjct: 6 VLVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELISGKKAEFAQLDVTDE 65 Query: 73 QELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLVAPE 132 A D +D +++ A D+ Y +NV+ L Sbjct: 66 ----AAFDKVFEAHPDIDSVIHFAALKAVGESGEKPLDY---YHVNVYGTICL----LRS 114 Query: 133 MEKNGGGVILTITSMAAEN---------------KNINMTSYASSKAAAS 167 M ++ I+ +S Y ++K A Sbjct: 115 MVRHNVTNIVFSSSATVYGDATRFPDMIPIPEHCPLGPTNPYGNTKFAIE 164 >2PK3-A nrPDB Length = 321 Score = 63.7 bits (154), Expect = 7e-11, Method: Composition-based stats. Identities = 56/265 (21%), Positives = 85/265 (32%), Gaps = 55/265 (20%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSE 72 A+ITG +GK +A V + N +A DI Sbjct: 14 RALITGVAGFVGKYLANHLTEQNVEVFGTSRNNEA----------KLPNVEMISLDIMDS 63 Query: 73 QELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADF---RRAYELNVFSFFHLSQLV 129 Q + + K D + + A K + + + NVF H+ V Sbjct: 64 QRVKKVISDI-----KPDYIFHLAAKSSVK------DSWLNKKGTFSTNVFGTLHVLDAV 112 Query: 130 APEMEKNGGGVILTITS-------------MAAENKNINMTSYASSKAAASHLVRNMAFD 176 ILTI S ++ EN+ M+ Y SKA+ L R Sbjct: 113 RDSNLDC---RILTIGSSEEYGMILPEESPVSEENQLRPMSPYGVSKASVGMLARQYVKA 169 Query: 177 LGEKNI---RVNGIAP----GAILTDALKSVITPEIEQ-----KMLQHTPIRRLGQPQDI 224 G I N I P G + D K ++ E+E+ K+ +R +DI Sbjct: 170 YGMDIIHTRTFNHIGPGQSLGFVTQDFAKQIVDIEMEKQEPIIKVGNLEAVRDFTDVRDI 229 Query: 225 ANAALFLCSPAASWVSGQILTVSGG 249 A +L S +G + V G Sbjct: 230 VQAY-WLLSQYGK--TGDVYNVCSG 251 >1OOE-A nrPDB Length = 236 Score = 59.4 bits (143), Expect = 2e-09, Method: Composition-based stats. Identities = 38/199 (19%), Positives = 71/199 (35%), Gaps = 19/199 (9%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDI 69 GK I+ G +G I F G +V+ D++A + Sbjct: 3 SGKV-IVYGGKGALGSAILEFFKKNGYTVLNIDLSA----------NDQADSNILVDGNK 51 Query: 70 TSEQELSALADFAISKL--GKVDILVNNAGGGGPKPFDMP--MADFRRAYELNVFSFFHL 125 ++ ++ + S L +VD + AGG + + + +V+S Sbjct: 52 NWTEQEQSILEQTASSLQGSQVDGVFCVAGGWAGGSASSKDFVKNADLMIKQSVWSSAIA 111 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLG--EKNIR 183 ++L ++ GG++ + AA +M Y +KAA HL ++A N Sbjct: 112 AKLATTHLK--PGGLLQLTGAAAAMGPTPSMIGYGMAKAAVHHLTSSLAAKDSGLPDNSA 169 Query: 184 VNGIAPGAILTDALKSVIT 202 V I P + T + + Sbjct: 170 VLTIMPVTLDTPMNRKWMP 188 >1UDA-A nrPDB Length = 338 Score = 55.2 bits (132), Expect = 3e-08, Method: Composition-based stats. Identities = 30/174 (17%), Positives = 57/174 (32%), Gaps = 25/174 (14%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQA-FACRCDITS 71 ++TG IG + G V++ D ++ V+ I++LGG+ DI + Sbjct: 2 RVLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVIERLGGKHPTFVEGDIRN 61 Query: 72 EQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLVAP 131 E AL + +D +++ AG ++ Y+ NV L Sbjct: 62 E----ALMTEILHDH-AIDTVIHFAGLKAVGESVQKPLEY---YDNNVNGTLRLISA--- 110 Query: 132 EMEKNGGGVILTITSMAAENKNIN------------MTSYASSKAAASHLVRNM 173 M + +S N + Y SK ++ ++ Sbjct: 111 -MRAANVKNFIFSSSATVYGDNPKIPYVESFPTGTPQSPYGKSKLMVEQILTDL 163 >6BWL-A nrPDB Length = 328 Score = 55.2 bits (132), Expect = 3e-08, Method: Composition-based stats. Identities = 41/265 (15%), Positives = 83/265 (31%), Gaps = 37/265 (13%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSE 72 ++TG IG+ + V + D A++ + E + DI + Sbjct: 2 KILVTGGAGFIGRWVVKRLLQDKHEVWILDNLANSTTANITEFAHDLNLKQCIQGDIKDK 61 Query: 73 QELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLVAPE 132 + ++ L + + L + + D R +E + F+L + Sbjct: 62 KLVAQLFEN--NSFDLCYHLAASINVQD------SIDDARATFENDTIGTFNLLEQCLNY 113 Query: 133 ----------MEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVR--NMAFDLGEK 180 M + I ++ + + YA SK AA ++V A+ L Sbjct: 114 DVKMVFMSTCMVYDKA---TNIQGISELDPIKPASPYAGSKIAAENMVLSYYYAYKLPVV 170 Query: 181 NIR-VNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQ---------PQDIANAALF 230 IR N G + + L + P+ G +D A+ + Sbjct: 171 VIRPFNTY--GPFQKTGGEGGVVAIFINNKLDNVPLNIYGDGKQTRDLLYVEDCADFVV- 227 Query: 231 LCSPAASWVSGQILTVSGGGVQELN 255 + ++ +G I+ G +N Sbjct: 228 -AAGYSAKANGHIINAGTGQDISIN 251 >1DIR-A nrPDB Length = 241 Score = 54.4 bits (130), Expect = 5e-08, Method: Composition-based stats. Identities = 37/238 (15%), Positives = 75/238 (31%), Gaps = 34/238 (14%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDI 69 + + ++ G +G F V D V E ++ D Sbjct: 6 EARRVLVYGGRGALGSRCVQAFRARNWWVASID---------VVENEEASASVIVKMTD- 55 Query: 70 TSEQELSALADFAISKLG--KVDILVNNAGGGGPKPFDMP--MADFRRAYELNVFSFFHL 125 + ++ + LG KVD ++ AGG + ++ ++++ Sbjct: 56 SFTEQADQVTAEVGKLLGDQKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSIWTSTIS 115 Query: 126 SQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMA--FDLGEKNIR 183 S L +++ GG++ + AA + M Y +K A L +++A Sbjct: 116 SHLATKHLKE--GGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKNSGMPSGAA 173 Query: 184 VNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVSG 241 + P + T + + E TP+ FL W++G Sbjct: 174 AIAVLPVTLDTPMNRKSMP---EADFSSWTPLE-------------FLVETFHDWITG 215 >3RFT-A nrPDB Length = 267 Score = 50.2 bits (119), Expect = 9e-07, Method: Composition-based stats. Identities = 27/172 (15%), Positives = 55/172 (31%), Gaps = 39/172 (22%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITS 71 K ++TGA +G+ + A + ++D++ + G +CD+ Sbjct: 4 KRLLVTGAAGQLGRVMRERLAPMAEILRLADLSP---------LDPAGPNEECVQCDLAD 54 Query: 72 EQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLVAP 131 ++A+ D +V+ G KP F + + N+ ++L + Sbjct: 55 ANAVNAMVA-------GCDGIVHLGGISVEKP-------FEQILQGNIIGLYNLYEAA-- 98 Query: 132 EMEKNGGGVILTITSMAAENKNINM------------TSYASSKAAASHLVR 171 +G I+ +S Y SK +L R Sbjct: 99 --RAHGQPRIVFASSNHTIGYYPQTERLGPDVPARPDGLYGVSKCFGENLAR 148 >3ENK-A nrPDB Length = 341 Score = 49.8 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 33/77 (42%), Gaps = 2/77 (2%) Query: 6 NLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQ-LGGQAFA 64 ++ G ++TG IG A+ G VV++D ++ + I++ G Sbjct: 1 SMSTKG-TILVTGGAGYIGSHTAVELLAHGYDVVIADNLVNSKREAIARIEKITGKTPAF 59 Query: 65 CRCDITSEQELSALADF 81 D++ E+ L+ + D Sbjct: 60 HETDVSDERALARIFDA 76 >1VL0-A nrPDB Length = 292 Score = 49.4 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 26/172 (15%), Positives = 55/172 (31%), Gaps = 45/172 (26%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSE 72 +ITGA +G+EI V+ +D+ DIT+ Sbjct: 14 KILITGANGQLGREIQKQLKGKNVEVIPTDVQD---------------------LDITNV 52 Query: 73 QELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLVAPE 132 ++ + K ++++N A D + AY++N +L+ Sbjct: 53 LAVNKFFNE-----KKPNVVINCAA---HTAVDKCEEQYDLAYKINAIGPKNLAAAAYSV 104 Query: 133 MEKNGGGVILTITSMAAENKNIN-----------MTSYASSKAAASHLVRNM 173 G I+ I++ + ++Y +K + V+ + Sbjct: 105 -----GAEIVQISTDYVFDGEAKEPITEFDEVNPQSAYGKTKLEGENFVKAL 151 >3SXP-A nrPDB Length = 362 Score = 49.0 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 34/201 (16%), Positives = 66/201 (32%), Gaps = 36/201 (17%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAG--ASVVVSD-------INADAANHVVDEIQQLG 59 L+ + +ITG +G +A F A VVV D + + + + +G Sbjct: 8 LENQTILITGGAGFVGSNLAFHFQENHPKAKVVVLDKFRSNTLFSNNRPSSLGHFKNLIG 67 Query: 60 GQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNV 119 + DI + +L L D L + A + + + N Sbjct: 68 FKGEVIAADINNPLDLRRLEKL------HFDYLFHQAAVSDTTMLNQEL-----VMKTNY 116 Query: 120 FSFFHLSQLVAPEMEKNGGGVILTITS--MAAENKNINM--------TSYASSKAAASHL 169 +F +L ++ ++ ++ +S + K N+ Y SK Sbjct: 117 QAFLNLLEIA-----RSKKAKVIYASSAGVYGNTKAPNVVGKNESPENVYGFSKLCMDEF 171 Query: 170 VRNMAFDLGEKNIR-VNGIAP 189 V + + D + +R N P Sbjct: 172 VLSHSNDNVQVGLRYFNVYGP 192 >5B6K-A nrPDB Length = 366 Score = 48.7 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 25/141 (17%), Positives = 49/141 (34%), Gaps = 14/141 (9%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSE 72 ++GA I + + V+ S +A+ +H+ + I + G + DI+ Sbjct: 23 TVFVSGATGFIAQHVVRQLLDQNYKVIGSVRSAEKGDHLKNVIFKGGDFNYEIVKDISDP 82 Query: 73 QELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLVAPE 132 D K GK DI V PF D + + + ++ + Sbjct: 83 ----TAFDHVFEKHGK-DIKVV---LHTASPFHFNTTDIEKDL---LIPAVNGTKGILES 131 Query: 133 MEK---NGGGVILTITSMAAE 150 ++K ++ +S AA Sbjct: 132 IKKYAAQTVERVVVTSSFAAN 152 >1I3M-A nrPDB Length = 348 Score = 47.9 bits (113), Expect = 4e-06, Method: Composition-based stats. Identities = 33/186 (17%), Positives = 55/186 (29%), Gaps = 41/186 (22%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSD------INADAANHVVDEIQQL-GGQAFAC 65 ++TG IG + AG VV D + + +Q+L G Sbjct: 4 KVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFE 63 Query: 66 RCDITSEQELSALADF----AISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFS 121 DI + L L A+ + + G KP D Y +N+ Sbjct: 64 EMDILDQGALQRLFKKYSFMAVIHFAGLKAM----GESVQKPLDY--------YRVNLTG 111 Query: 122 FFHLSQLVAPEMEKNGGGVILTITSMAAENKNINM-------------TSYASSKAAASH 168 L M+ +G ++ +S A N Y SK Sbjct: 112 TIQL----LEIMKAHGVKNLVF-SSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEE 166 Query: 169 LVRNMA 174 ++R++ Sbjct: 167 MIRDLC 172 >2GN9-A nrPDB Length = 344 Score = 47.9 bits (113), Expect = 4e-06, Method: Composition-based stats. Identities = 24/164 (14%), Positives = 52/164 (31%), Gaps = 20/164 (12%) Query: 1 MFNSDNLRLDGKCAIITGAGAGIGKEIAIT-FATAGASVVVSDINADAANHVVDEIQQLG 59 M N N+ LD + +ITG GK T A ++ + D ++ Sbjct: 12 MPNHQNM-LDNQTILITGGTGSFGKCFVRKVLDTTNAKKIIVY-SRDELKQSEMAMEFND 69 Query: 60 GQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNV 119 + D+ + L+ + VDI ++ A + + N+ Sbjct: 70 PRMRFFIGDVRDLERLNYALE-------GVDICIHAAALKHVPIAEYNP---LECIKTNI 119 Query: 120 FSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSK 163 ++ ++ +++ A N + Y ++K Sbjct: 120 MGASNVINACLKNAISQ----VIALSTDKAANP---INLYGATK 156 >2Q1W-A nrPDB Length = 333 Score = 46.3 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 34/193 (17%), Positives = 54/193 (27%), Gaps = 41/193 (21%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITS 71 K ITG IG IA G VV D A + + I Sbjct: 22 KKVFITGICGQIGSHIAELLLERGDKVVGIDNFATGRREHLKD----HPNLTFVEGSIAD 77 Query: 72 EQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLVAP 131 ++ L + D +V+ A D+ N ++ Q Sbjct: 78 HALVNQLIGDL-----QPDAVVHTAASYKD------PDDWYNDTLTNCVGGSNVVQAA-- 124 Query: 132 EMEKNGGGVILTITSMAAENK-------------NINMTSYASSKAA---------ASHL 169 +KN G + + N +SYA SK+A + Sbjct: 125 --KKNNVGRFVYFQTALCYGVKPIQQPVRLDHPRNPANSSYAISKSANEDYLEYSGLDFV 182 Query: 170 VRNMAFDLGEKNI 182 +A +G +N+ Sbjct: 183 TFRLANVVGPRNV 195 >4PVC-A nrPDB Length = 342 Score = 45.6 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 25/139 (17%), Positives = 50/139 (35%), Gaps = 14/139 (10%) Query: 14 AIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQ 73 ++GA I + I V+ S + + A ++ + + DI+ Sbjct: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62 Query: 74 ELSALADFAISKLGK-VDILVNNAGGGGPKPFDMPMADFRRAY-ELN-VFSFFHLSQLVA 130 D K GK + I+++ A P FD+ ++ +N V H + A Sbjct: 63 ----AFDHVFQKHGKDIKIVLHTA---SPFCFDITDSERDLLIPAVNGVKGILHSIKKYA 115 Query: 131 PEMEKNGGGVILTITSMAA 149 + + ++ +S AA Sbjct: 116 ADSVE----RVVLTSSYAA 130 >1RKX-A nrPDB Length = 357 Score = 44.8 bits (105), Expect = 4e-05, Method: Composition-based stats. Identities = 39/230 (16%), Positives = 77/230 (33%), Gaps = 40/230 (17%) Query: 10 DGKCAIITG--AGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 GK +TG G G +++ T GA+V + A V + + A + Sbjct: 8 QGKRVFVTGHTGFKG-GW-LSLWLQTMGATVKGYSLTAP----TVPSLFETARVADGMQS 61 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQ 127 +I ++ + L + + +I+ + A + ++ Y NV +L + Sbjct: 62 EIGDIRDQNKLLESIREF--QPEIVFHMAAQP---LVRLSYSEPVETYSTNVMGTVYLLE 116 Query: 128 LVAPEMEKNGGG--VILTITS------------MAAENKNINMTSYASSKAAASHLVRNM 173 ++ GG ++ ITS Y++SK A + + Sbjct: 117 A-----IRHVGGVKAVVNITSDKCYDNKEWIWGYRENEAMGGYDPYSNSKGCAELVTSSY 171 Query: 174 AF------DLGEKNIRVNGIAPGAI--LTDALKSVITPEIEQKMLQHTPI 215 + G+ V + G + D I P+I + Q P+ Sbjct: 172 RNSFFNPANYGQHGTAVATVRAGNVIGGGDWALDRIVPDILRAFEQSQPV 221 >6ACF-A nrPDB Length = 367 Score = 44.8 bits (105), Expect = 4e-05, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 27/65 (41%), Gaps = 4/65 (6%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLG---GQAFA 64 L+GK + G G + + GA ++V+DIN +A V+E + Sbjct: 170 SLEGKVVAVQGVGN-VAYHLCRHLHEEGAKLIVTDINKEAVARAVEEFGAKAVDPNDIYG 228 Query: 65 CRCDI 69 CDI Sbjct: 229 VECDI 233 >1Z45-A nrPDB Length = 699 Score = 44.4 bits (104), Expect = 4e-05, Method: Composition-based stats. Identities = 27/179 (15%), Positives = 57/179 (31%), Gaps = 30/179 (16%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAF-ACRCDIT 70 K ++TG IG + G VV+D +++ V ++ L D+ Sbjct: 12 KIVLVTGGAGYIGSHTVVELIENGYDCVVADNLSNSTYDSVARLEVLTKHHIPFYEVDLC 71 Query: 71 SEQELSALADFAISKLGKVDILVNNAGG-GGPKPFDMPMADFRRAYELNVFSFFHLSQLV 129 + L + K+D +++ AG + +P+ R Y N+ L Sbjct: 72 DRKGLEKVFKEY-----KIDSVIHFAGLKAVGESTQIPL----RYYHNNILGTVVL---- 118 Query: 130 APEMEKNGGGVILTITSMAAEN---------------KNINMTSYASSKAAASHLVRNM 173 M++ + +S Y +K A +++ ++ Sbjct: 119 LELMQQYNVSKFVFSSSATVYGDATRFPNMIPIPEECPLGPTNPYGHTKYAIENILNDL 177 >4G5H-A nrPDB Length = 363 Score = 44.4 bits (104), Expect = 5e-05, Method: Composition-based stats. Identities = 19/165 (11%), Positives = 48/165 (29%), Gaps = 20/165 (12%) Query: 4 SDNLRLDGKCAIITGAGAGIGKEIAITFATAGAS-VVVSDINADAANHVVDEIQQLGGQA 62 + D K +ITG G + F + + + + + + + + Sbjct: 18 GSAMGFDDKILLITGGTGSFGNAVMKRFLDSNIKEIRIFSRDEKKQDDIRK--KYNNSKL 75 Query: 63 FACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSF 122 D+ Q + VD + + A + + A + N+ Sbjct: 76 KFYIGDVRDSQSVETAMRD-------VDYVFHAAALKQVPSCEFFPVE---AVKTNIIGT 125 Query: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAAS 167 ++ Q + K ++ ++ + + + SKA Sbjct: 126 ENVLQSAIHQNVKK----VICLS---TDKAAYPINAMGISKAMME 163 >1GY8-A nrPDB Length = 397 Score = 44.0 bits (103), Expect = 6e-05, Method: Composition-based stats. Identities = 39/207 (18%), Positives = 65/207 (31%), Gaps = 49/207 (23%) Query: 13 CAIITGAGAGIGKEIAITFATA-GASVVVSDI---------NADAANHVVDEIQQLGGQ- 61 ++ G IG SVV+ D + + +V ++QQ G Sbjct: 4 RVLVCGGAGYIGSHFVRALLRDTNHSVVIVDSLVGTHGKSDHVETRENVARKLQQSDGPK 63 Query: 62 -------AFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRA 114 A D+ +E + ++ G +D +V+ + D + Sbjct: 64 PPWADRYAALEVGDVRNED----FLNGVFTRHGPIDAVVHMCAFLAVGE---SVRDPLKY 116 Query: 115 YELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINM------------------ 156 Y+ NV L Q M + I+ +S AA N M Sbjct: 117 YDNNVVGILRLLQA----MLLHKCDKIIF-SSSAAIFGNPTMGSVSTNAEPIDINAKKSP 171 Query: 157 -TSYASSKAAASHLVRNMAFDLGEKNI 182 + Y SK A ++R+ A G K I Sbjct: 172 ESPYGESKLIAERMIRDCAEAYGIKGI 198 >2PZM-A nrPDB Length = 330 Score = 42.9 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 18/120 (15%), Positives = 36/120 (30%), Gaps = 15/120 (12%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSE 72 +ITG +G + + G ++V D A V+ + L +T Sbjct: 22 RILITGGAGCLGSNLIEHWLPQGHEILVIDNFATGKREVLPPVAGLS----VIEGSVTDA 77 Query: 73 QELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLVAPE 132 L D +V++A D+ NV ++++ + Sbjct: 78 GLLERAFDSFKPTH-----VVHSAAAYKD------PDDWAEDAATNVQGSINVAKAASKA 126 >1OC2-A nrPDB Length = 348 Score = 42.1 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 21/122 (17%), Positives = 35/122 (28%), Gaps = 11/122 (9%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQ-LGGQAFACRCDIT 70 K I+TG IG V V+ ++ ++ LG + DI Sbjct: 5 KNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNKANLEAILGDRVELVVGDIA 64 Query: 71 SEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLVA 130 + + LA A D +V+ A + F N + L + Sbjct: 65 DAELVDKLAAKA-------DAIVHYAAESHNDNSLNDPSPF---IHTNFIGTYTLLEAAR 114 Query: 131 PE 132 Sbjct: 115 KY 116 >5N2I-A nrPDB Length = 232 Score = 41.7 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 23/49 (46%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQ 57 + G + G G+ +A FA AG V++ +A+ A V E+ + Sbjct: 17 VSGLSIAVLGGTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAELGE 65 >3HFS-A nrPDB Length = 338 Score = 41.7 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 23/141 (16%), Positives = 43/141 (30%), Gaps = 17/141 (12%) Query: 11 GKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHV--VDEIQQLGGQAFACRCD 68 K A + G + + G +V + + D V + E+Q+LG R D Sbjct: 9 KKTACVVGGTGFVASLLVKLLLQKGYAVNTTVRDPDNQKKVSHLLELQELG-DLKIFRAD 67 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQL 128 +T E A D + + A D + A + ++ + Sbjct: 68 LTDELSFEAPIA-------GCDFVFHVATPVHFASEDPENDMIKPAIQ----GVVNVMKA 116 Query: 129 VAPEMEKNGGGVILTITSMAA 149 ++ +S AA Sbjct: 117 CTRAKSVK---RVILTSSAAA 134 >1LU9-A nrPDB Length = 287 Score = 41.3 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 25/75 (33%), Gaps = 1/75 (1%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 + GK A++ +G A A GA VV+ D A D + + + Sbjct: 116 SVKGKKAVVLAGTGPVGMRSAALLAGEGAEVVLCGRKLDKAQAAADSVNKR-FKVNVTAA 174 Query: 68 DITSEQELSALADFA 82 + + + A Sbjct: 175 ETADDASRAEAVKGA 189 >4KTT-E nrPDB Length = 327 Score = 41.3 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 20/145 (13%), Positives = 45/145 (31%), Gaps = 27/145 (18%) Query: 2 FNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQ 61 + + + + ++TGA +G+ + F V Sbjct: 12 MEQEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPK------------ 59 Query: 62 AFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFS 121 + ++ S I + ++V+ A P + A +LNV + Sbjct: 60 --FEQVNLLD----SNAVHHIIHDF-QPHVIVHCAAERRPDVVENQP---DAASQLNVDA 109 Query: 122 FFHLSQLVAPEMEKNGGGVILTITS 146 +L++ A G ++ I+S Sbjct: 110 SGNLAKEAAAV-----GAFLIYISS 129 >6GCS-E nrPDB Length = 375 Score = 41.3 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 23/123 (18%), Positives = 43/123 (34%), Gaps = 16/123 (13%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDI 69 G A + GA +G + A G +VVV + A + LG D+ Sbjct: 52 TGYTATVFGANGFLGSYLTAKLAKHGTTVVVPYR-EEMAKRHLKVTGDLGV-VNFLEMDL 109 Query: 70 TSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLV 129 + + + + DI+VN G + +F Y+++V +++ V Sbjct: 110 RNLESIDEAVRHS-------DIVVNLIG------REYETKNFNY-YDVHVEGARRIAEAV 155 Query: 130 APE 132 Sbjct: 156 KKH 158 >1WVG-A nrPDB Length = 359 Score = 41.3 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 31/170 (18%), Positives = 52/170 (30%), Gaps = 30/170 (17%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDI 69 GK +TG G +++ GA V ++A + EI +L + DI Sbjct: 8 QGKRVFVTGHTGFKGSWLSLWLTEMGAIVKGYALDAPTVPSLF-EIVRLNDLMESHIGDI 66 Query: 70 TSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLV 129 ++L + + I+ + A + + Y NV HL + V Sbjct: 67 RDFEKLRSSIAEFKPE-----IVFHMAAQP---LVRLSYEQPIKTYSTNVMGTVHLLETV 118 Query: 130 APEMEKNGGGVI---LTITS------------MAAENKNINMTSYASSKA 164 G I + ITS Y++SK Sbjct: 119 KQV------GNIKAVVNITSDKCYDNREWVWGYRENEPMGGYDPYSNSKG 162 >3VPX-A nrPDB Length = 364 Score = 40.9 bits (95), Expect = 6e-04, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 28/70 (40%), Gaps = 4/70 (5%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 L GK + G G + + GA ++++DIN +A VD G A Sbjct: 170 SLAGKTVAVQGVGN-VAYALCEYLHEEGAKLIITDINEEAVQRAVD---AFGATAVGINE 225 Query: 68 DITSEQELSA 77 + E ++ A Sbjct: 226 IYSQEADIFA 235 >3SC6-A nrPDB Length = 287 Score = 40.6 bits (94), Expect = 7e-04, Method: Composition-based stats. Identities = 26/181 (14%), Positives = 56/181 (30%), Gaps = 48/181 (26%) Query: 4 SDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAF 63 S+ ++ + IITGA +GK++ + D Sbjct: 1 SNAMK---ERVIITGANGQLGKQLQEELNPEEYDIYPFDKKL------------------ 39 Query: 64 ACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFF 123 DIT+ ++ + + I+++ A + AY +N Sbjct: 40 ---LDITNISQVQQVVQEI-----RPHIIIHCAAYTKVDQAEKER---DLAYVINAIGAR 88 Query: 124 HLSQLVAPEMEKNGGGVILTITSMAAENK-----------NINMTSYASSKAAASHLVRN 172 ++ VA ++ G ++ I++ + Y +SK A V+ Sbjct: 89 NV--AVASQLV---GAKLVYISTDYVFQGDRPEGYDEFHNPAPINIYGASKYAGEQFVKE 143 Query: 173 M 173 + Sbjct: 144 L 144 >1R66-A nrPDB Length = 337 Score = 40.2 bits (93), Expect = 8e-04, Method: Composition-based stats. Identities = 52/269 (19%), Positives = 79/269 (29%), Gaps = 50/269 (18%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGA-------SVVVSDINADAANHVVDEIQQLG 59 +RL ++TG IG AGA V+V D A N Sbjct: 1 MRL-----LVTGGAGFIGSHFVRQLL-AGAYPDVPADEVIVLDSLTYAGNRANLAPVDAD 54 Query: 60 GQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNV 119 + DI A +L VD +V+ A D +A E NV Sbjct: 55 PRLRFVHGDIRD-------AGLLARELRGVDAIVHFAAESH---VDRSIAGASVFTETNV 104 Query: 120 FSFFHLSQLVAPEMEKNGGGVILTIT-----------SMAAENKNINMTSYASSKAAASH 168 L Q G G ++ ++ S + + YA+SKA + Sbjct: 105 QGTQTLLQCAV----DAGVGRVVHVSTDEVYGSIDSGSWTESSPLEPNSPYAASKAGSDL 160 Query: 169 LVRNMAFDLGEK-NIR--VNGI----APGAILTDALKSVITPEIEQKMLQHTPIRRLGQP 221 + R G I N P ++ + +++ +R Sbjct: 161 VARAYHRTYGLDVRITRCCNNYGPYQHPEKLIPLFVTNLLDGGTLPLYGDGANVREWVHT 220 Query: 222 QD-IANAALFLCSPAASWVSGQILTVSGG 249 D AL L A G+I + GG Sbjct: 221 DDHCRGIALVLAGGRA----GEIYHIGGG 245 >2NNL-D nrPDB Length = 337 Score = 40.2 bits (93), Expect = 9e-04, Method: Composition-based stats. Identities = 30/266 (11%), Positives = 69/266 (25%), Gaps = 47/266 (17%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFAC- 65 + + +TGA IG + + G +V + + V + + Sbjct: 1 MGSQSETVCVTGASGFIGSWLVMRLLERGYTVRATVRDPTNVKKVKHLLDLPKAETHLTL 60 Query: 66 -RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFH 124 + D+ E + + A + D + E Sbjct: 61 WKADLADEGSFDEAIK-------GCTGVFHVATPMDFESKDPENEVIKPTIE----GMLG 109 Query: 125 LSQLVAPEMEKNGGGVILTITSMAAENKNINMTS-----------YASSK---AAASHLV 170 + + A ++ +S N + + +K A + Sbjct: 110 IMKSCAAAKTVR---RLVFTSSAGTVNIQEHQLPVYDESCWSDMEFCRAKKMTAWMYFVS 166 Query: 171 RNMAFDLG-----EKNIRVNGIAPGAILTDALKSVITPEI---------EQKMLQHTPIR 216 + +A E NI I P ++ + S + P + + Sbjct: 167 KTLAEQAAWKYAKENNIDFITIIPTLVVGPFIMSSMPPSLITALSPITGNEAHYSIIRQG 226 Query: 217 RLGQPQDIANAALFLCSP---AASWV 239 + D+ NA ++L ++ Sbjct: 227 QFVHLDDLCNAHIYLFENPKAEGRYI 252 >4EUF-A nrPDB Length = 418 Score = 39.8 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 20/120 (16%), Positives = 40/120 (33%), Gaps = 15/120 (12%) Query: 2 FNSDNLRLDG-KCAIITGAGAGIGKE--IAITFATAGASVVVSDINADAANHVV------ 52 + + G K +I GA +G G I++ F A + A + + Sbjct: 50 YCKKAIGFRGPKKVLIVGASSGFGLATRISVAFGGPEAHTIGVSYETGATDRRIGTAGWY 109 Query: 53 ------DEIQQLGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDM 106 + ++ G A D S + + + + GK+D+ V + K + Sbjct: 110 NNIFFKEFAKKKGLVAKNFIEDAFSNETKDKVIKYIKDEFGKIDLFVYSLAAPRRKDYKT 169 >1DB3-A nrPDB Length = 372 Score = 39.0 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 18/123 (14%), Positives = 36/123 (29%), Gaps = 13/123 (10%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASV-----VVSDINADAANHVVDEIQQLGGQAFACR 66 K A+ITG G +A G V S N + +H+ + + Sbjct: 2 KVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPHTCNPKFHLHY 61 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLS 126 D++ L+ + V N G ++ +++ L Sbjct: 62 GDLSDTSNLTRILREVQPDE------VYNLGAMSHVAVSFESPEYTA--DVDAMGTLRLL 113 Query: 127 QLV 129 + + Sbjct: 114 EAI 116 >2Z95-A nrPDB Length = 345 Score = 38.6 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 26/78 (33%), Gaps = 6/78 (7%) Query: 9 LDGKCAIITGAGAGI-GKEIAITFATAGASVVVSDINADAANHVVDEIQQLG--GQAFAC 65 + GK A+ITG G G +A G V +D + +++LG Sbjct: 1 MSGKRALITGI-RGQDGAYLAKLLLEKGYEVYGADR--RSGEFASWRLKELGIENDVKII 57 Query: 66 RCDITSEQELSALADFAI 83 D+ + + Sbjct: 58 HMDLLEFSNIIRTIEKVQ 75 >2GGS-A nrPDB Length = 273 Score = 38.3 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 21/114 (18%), Positives = 44/114 (38%), Gaps = 23/114 (20%) Query: 15 IITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQE 74 +ITGA +G E++ + V+ +++ + D+T Sbjct: 4 LITGASGQLGIELSRLLSER-HEVIKVYNSSEIQG--------------GYKLDLTD--- 45 Query: 75 LSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQL 128 L DF I K + D+++N A ++ +AY++N + H+ + Sbjct: 46 FPRLEDFIIKK--RPDVIINAAAMTDVDKCEIEKE---KAYKINAEAVRHIVRA 94 >3OND-A nrPDB Length = 488 Score = 38.3 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 2/61 (3%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGASVVVSDINAD-AANHVVDEIQQLGGQAFACRCD 68 GK A++ G G +GK A AGA V+V++I+ A ++ +Q L + D Sbjct: 264 AGKVAVVAGYGD-VGKGCAAALKQAGARVIVTEIDPICALQATMEGLQVLTLEDVVSEAD 322 Query: 69 I 69 I Sbjct: 323 I 323 >6DEB-A nrPDB Length = 285 Score = 38.3 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 15/44 (34%), Positives = 24/44 (54%) Query: 1 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN 44 + + + L+GK A+I GA +G+ +A AGA+V V I Sbjct: 150 LLKAYEIDLEGKDAVIIGASNIVGRPMATMLLNAGATVSVCHIK 193 >4J2O-A nrPDB Length = 363 Score = 38.3 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 17/160 (10%), Positives = 42/160 (26%), Gaps = 20/160 (12%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGAS-VVVSDINADAANHVVDEIQQLGGQAFACRC 67 K +ITG G + F + + + + + + + Sbjct: 21 FKDKVLLITGGTGSFGNAVLKRFLETDIKEIRIFSRDEKKQDDMRK--KYHSAKLKFYIG 78 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQ 127 D+ + VD + + A + A + NV ++ + Sbjct: 79 DVRDYNSILNATR-------GVDYIYHAAALKQVPSCEFHP---MEAVKTNVLGTENVLE 128 Query: 128 LVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAAS 167 K ++ ++ + + + SKA Sbjct: 129 AAIQNHVK----RVVCLS---TDKAVYPINAMGISKAMME 161 >1BXK-A nrPDB Length = 355 Score = 37.9 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 29/181 (16%), Positives = 58/181 (32%), Gaps = 27/181 (14%) Query: 12 KCAIITGAGAGIGKEIAITFATA-GASVVVSDINADAANHVVDEIQQLGGQAFACRCDIT 70 + +ITG IG + +VVV D A N + + + DI Sbjct: 2 RKILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSLAPVAQSERFAFEKVDIC 61 Query: 71 SEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLVA 130 EL+ + + D +++ A D + E N+ + L + Sbjct: 62 DRAELARVFTEH-----QPDCVMHLAAESH---VDRSIDGPAAFIETNIVGTYTLLEAAR 113 Query: 131 P---EMEKNGGGVI----LTITSMAAE-----------NKNINMTSYASSKAAASHLVRN 172 + ++ ++ + + + Y++SKA++ HLVR Sbjct: 114 AYWNALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPYSASKASSDHLVRA 173 Query: 173 M 173 Sbjct: 174 W 174 >1KEU-A nrPDB Length = 361 Score = 37.5 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 29/202 (14%), Positives = 63/202 (31%), Gaps = 37/202 (18%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVS--DINADAANHVVDEIQQLGGQAFACRCDIT 70 +ITG IG + VV+ + + +I + + DI Sbjct: 2 KILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISESN-RYNFEHADIC 60 Query: 71 SEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLVA 130 E++ + + + D +++ A A F E N+ + L ++ Sbjct: 61 DSAEITRIFEQY-----QPDAVMHLAAESHVDRSITGPAAF---IETNIVGTYALLEVAR 112 Query: 131 P---EMEKNGGGVI----LTITSMAAENKNIN-------------------MTSYASSKA 164 + ++ ++ + + + + + Y++SKA Sbjct: 113 KYWSALGEDKKNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTAYAPSSPYSASKA 172 Query: 165 AASHLVRNMAFDLGEKNIRVNG 186 ++ HLVR G I N Sbjct: 173 SSDHLVRAWRRTYGLPTIVTNC 194 >1ZZE-A nrPDB Length = 342 Score = 37.5 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 18/149 (12%), Positives = 41/149 (27%), Gaps = 17/149 (11%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDE--IQQLGGQAFACRC 67 +G ++TGA + + G V + +A ++ + G A Sbjct: 10 EGSLVLVTGANGFVASHVVEQLLEHGYKVRGTARSASKLANLQKRWDAKYPGRFETAVVE 69 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQ 127 D+ + + A AG + + + + Sbjct: 70 DMLKQGAYDEVIKGA-------------AGVAHIASVVSFSNKYDEVVTPAIGGTLNALR 116 Query: 128 LVAPEMEKNGGGVILTITSMAAENKNINM 156 A +LT ++++A N+ Sbjct: 117 AAAATPSVKRF--VLTSSTVSALIPKPNV 143 >5INT-A nrPDB Length = 220 Score = 37.1 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 20/113 (17%), Positives = 33/113 (29%), Gaps = 34/113 (30%) Query: 9 LDGKCAIITGA---------------GAG-IGKEIAITFATAGASVVVSDINADAANHVV 52 L GK +IT +G +G IA GA V++ Sbjct: 4 LQGKRILITAGPTREKIDPVRFMTNFSSGKMGYAIAEVAVNLGAEVILVS---------- 53 Query: 53 DEIQQLGGQAFACRCDIT--SEQELSALADFAISKLGKVDILVNNAGGGGPKP 103 G A +T + + + I VD+++ A +P Sbjct: 54 ------GPTALNPPLHVTTVQVESAQDMLEAVIQHYQNVDVVIKTAAVADYRP 100 >5JXW-A nrPDB Length = 498 Score = 37.1 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 33/203 (16%), Positives = 69/203 (33%), Gaps = 51/203 (25%) Query: 1 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG 60 +FN L GK ++ G G +GK A + GA V+V++I D I L Sbjct: 261 LFNGCIQMLAGKKIVVLGYGE-VGKGCAQGLSGVGARVIVTEI---------DPICALQA 310 Query: 61 QAFACRCDITSEQELSALADFAISKLGKVDIL-------------VNNAGGGGPKPFDMP 107 + ++ +++ + AD I+ G D++ + N G + Sbjct: 311 SMEGYQ--VSVLEDVVSEADIFITATGNKDVITVEHMRKMKENAYIANIGHFDDEIDVYG 368 Query: 108 MADF--RRAYEL--NV---------FSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNI 154 + ++ + E+ NV S L + G ++ + Sbjct: 369 LENYPGIKVIEVKQNVHKFTFPDTQKSVILLCK-----------GRLVNLGCATGH--PP 415 Query: 155 NMTSYASSKAAASHLVRNMAFDL 177 + S + + + + + +L Sbjct: 416 LVMSMSFTNQVLAQMDLWKSREL 438 >6G2J-P nrPDB Length = 377 Score = 37.1 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 17/123 (13%), Positives = 43/123 (34%), Gaps = 14/123 (11%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 + G A + GA +G+ + G+ V++ D + + + GQ Sbjct: 50 SVSGVVATVFGATGFLGRYVVNHLGRMGSQVIIPYRC-DVYDIMHLRLMGDLGQLTFLEW 108 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNV-FSFFHLS 126 D + + + ++++N G + ++ DF + +N+ + S Sbjct: 109 DARDKDSIRKAVQHS-------NVVINLIG----REWETRNFDFEDVF-VNIPRAIAQAS 156 Query: 127 QLV 129 + Sbjct: 157 KEA 159 >4K28-A nrPDB Length = 269 Score = 37.1 bits (85), Expect = 0.008, Method: Composition-based stats. Identities = 24/102 (23%), Positives = 41/102 (40%), Gaps = 3/102 (2%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAG-ASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 GK A++ G G G+G IA A AG AS+ + D + V + + G Sbjct: 124 AGKRALVIGCG-GVGSAIAYALAEAGIASITLCDPSTARMGAVCELLG-NGFPGLTVSTQ 181 Query: 69 ITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD 110 + ++ +A+ + +G L +A D +AD Sbjct: 182 FSGLEDFDLVANASPVGMGTRAELPLSAALLATLQPDTLVAD 223 >4KUG-A nrPDB Length = 290 Score = 37.1 bits (85), Expect = 0.008, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 23/53 (43%), Gaps = 1/53 (1%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFA 64 K + GAG +G I FA G V+V DI + + + I + + A Sbjct: 2 KKVFVLGAGT-MGAGIVQAFAAKGCEVIVRDIKEEFVDRGIATITKSLSKLVA 53 >3LK7-A nrPDB Length = 451 Score = 36.7 bits (84), Expect = 0.009, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 20/55 (36%), Gaps = 1/55 (1%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAF 63 + K ++ G G+ A A GA V V+D N + + G + Sbjct: 7 FENKKVLVLGLARS-GEAAARLLAKLGAIVTVNDGKPFDENPTAQSLLEEGIKVV 60 >4EJ0-A nrPDB Length = 342 Score = 36.7 bits (84), Expect = 0.010, Method: Composition-based stats. Identities = 31/168 (18%), Positives = 53/168 (31%), Gaps = 31/168 (18%) Query: 15 IITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQE 74 I+TGA IG + G + +++ N A+ + + C+I + Sbjct: 16 IVTGAAGFIGANLVKALNERGETRIIAVDNLTRADKFKNLVD----------CEIDDYLD 65 Query: 75 LSALAD-FAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLVAPEM 133 + + FA GKV + + D D R + N F S+ V Sbjct: 66 KTEFVERFARGDFGKVRAVFH-----EGACSDTMETDGRYMMDNN----FRYSRAVLDAC 116 Query: 134 EKNGGGVILTITSMAAENKN----------INMTSYASSKAAASHLVR 171 G L +S A + + Y SK ++R Sbjct: 117 LAQ-GAQFLYASSAAIYGGSSRFVEEREVEAPLNVYGYSKFLFDQVIR 163 >2GAS-A nrPDB Length = 307 Score = 36.7 bits (84), Expect = 0.010, Method: Composition-based stats. Identities = 21/91 (23%), Positives = 33/91 (36%), Gaps = 15/91 (16%) Query: 13 CAIITGAGAGIGKEIAITFATAG---ASVV---VSDINADAANHVVDEIQQLGGQAFACR 66 +I G IG+ I AG ++V ++ N + ++D Q LG Sbjct: 4 KILILGPTGAIGRHIVWASIKAGNPTYALVRKTITAANPETKEELIDNYQSLG--VILLE 61 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAG 97 DI + L VDI++ AG Sbjct: 62 GDINDHETLVKAIKQ-------VDIVICAAG 85 >5K1S-A nrPDB Length = 362 Score = 36.3 bits (83), Expect = 0.011, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 27/80 (33%), Gaps = 3/80 (3%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQL--GGQAFACRC 67 G+ +ITGA G+G GA V+ + + + + Sbjct: 183 AGETVLITGASGGVGLSSVQLARLDGARVIAVTSSEAKVQALKEAGADEVIVSRGLDFAS 242 Query: 68 DITSEQELSALADFAISKLG 87 D+ + A D A+ +G Sbjct: 243 DVRKRTQ-GAGVDVAVEIVG 261 >6ACQ-A nrPDB Length = 302 Score = 36.3 bits (83), Expect = 0.014, Method: Composition-based stats. Identities = 16/46 (34%), Positives = 23/46 (50%), Gaps = 1/46 (2%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQ 57 K + GAG +G IA FA G VV+ DI + + +D I + Sbjct: 22 KKVCVIGAGT-MGSGIAQAFAAKGFEVVLRDIKDEFVDRGLDFINK 66 >4WPG-A nrPDB Length = 289 Score = 35.6 bits (81), Expect = 0.020, Method: Composition-based stats. Identities = 21/140 (15%), Positives = 42/140 (30%), Gaps = 33/140 (23%) Query: 14 AIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQ 73 +ITG+ +G E+ G V D DIT+E Sbjct: 7 ILITGSNGQLGTELRYLLDERGVDYVAVD---------------------VAEMDITNED 45 Query: 74 ELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLVAPEM 133 ++ A+ L + + A + A +NV ++++ Sbjct: 46 KVEAVFAQVKPTL-----VYHCAAYTAVDAAEDEGKALNEA--INVTGSENIAKACGKY- 97 Query: 134 EKNGGGVILTITSMAAENKN 153 G ++ I++ + N Sbjct: 98 ----GATLVYISTDYVFDGN 113 >5YWN-A nrPDB Length = 334 Score = 35.6 bits (81), Expect = 0.020, Method: Composition-based stats. Identities = 25/142 (17%), Positives = 55/142 (38%), Gaps = 16/142 (11%) Query: 14 AIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQ 73 ++GA + ++I + G VV S + + +++L G F+ + Sbjct: 5 VFVSGATGYLAQQIIALVLSKGYKVVGSVRSEEKG----ANLKKLYGDDFSYE--VVKVL 58 Query: 74 ELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAY-ELNVFSFFH-LSQLVAP 131 E D A+ K +V I ++ A P F++ + +N + + VAP Sbjct: 59 EQKGAFDEALKKHPEVTIFLHTA---SPVTFEVEDTEKEILIPAINGTKYVLQSIKDVAP 115 Query: 132 EMEKNGGGVILTITSMAAENKN 153 ++ ++ +S+ A + Sbjct: 116 QIT-----RVVYTSSVVAMSVP 132 >2EXX-A nrPDB Length = 306 Score = 35.6 bits (81), Expect = 0.024, Method: Composition-based stats. Identities = 15/87 (17%), Positives = 29/87 (33%), Gaps = 5/87 (5%) Query: 1 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAG-ASVVVSDINADAANHVVDEIQQLG 59 ++ L +D K ++ G G +A T G V V N E++ G Sbjct: 1 LYKKAGLMVDKKLVVVFGGTGAQGGSVARTLLEDGTFKVRVVTRNPR--KKAAKELRLQG 58 Query: 60 GQAFACRCDITSEQELSALADFAISKL 86 + + D + + + A + Sbjct: 59 AEV--VQGDQDDQVIMELALNGAYATF 83 >1E3J-A nrPDB Length = 352 Score = 35.2 bits (80), Expect = 0.031, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 31/79 (39%), Gaps = 7/79 (8%) Query: 11 GKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDIT 70 G ++ GAG IG + GA VV + + E+ + G D Sbjct: 169 GTTVLVIGAGP-IGLVSVLAAKAYGAFVVCTARSPRRL-----EVAKNCGADVTLVVDPA 222 Query: 71 SEQELSALADFAISKLGKV 89 E+E S++ + S +G + Sbjct: 223 KEEE-SSIIERIRSAIGDL 240 >4J6F-A nrPDB Length = 382 Score = 35.2 bits (80), Expect = 0.032, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 27/80 (33%), Gaps = 24/80 (30%) Query: 10 DGKCAIITGAGAGIGKEIAITFATA--------------------GASVVVSDINADAAN 49 G+ ++TGA G+G I I A A GA VV+ D A Sbjct: 206 AGETVLVTGASGGVGSAI-IQLARARGAVPIAVAGPGKEAAMLDIGAQAVVTRGQGDLAE 264 Query: 50 HVVDEIQQLGGQAFACRCDI 69 V GG+ D+ Sbjct: 265 AVE---AASGGRPIDVVADL 281 >5GUP-L nrPDB Length = 377 Score = 34.8 bits (79), Expect = 0.035, Method: Composition-based stats. Identities = 26/165 (15%), Positives = 60/165 (36%), Gaps = 21/165 (12%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 + G A + GA +G+ + G+ V+V + + LG Q Sbjct: 50 SVSGIVATVFGATGFLGRYVVNHLGRMGSQVIVPYRCEPYDTMHLRPMGDLG-QIIFMEW 108 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQ 127 + + + + + + ++++N G + ++ DF + + Sbjct: 109 NGKDKDSIRKVVEHS-------NVVINLVG----REWETKNFDFEDVF-------VKIPH 150 Query: 128 LVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRN 172 +A ++ G ++ I+ + A+ K+ + Y SKA VR Sbjct: 151 AIAQVSKEAGVEKLIHISHLNADIKSP--SRYLRSKAVGEKEVRA 193 >2Q4B-A nrPDB Length = 253 Score = 34.8 bits (79), Expect = 0.035, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 28/81 (34%), Gaps = 12/81 (14%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSE 72 ++TGA G+ I G+ V A +++GG+A DIT Sbjct: 6 TVLVTGASGRTGQ-IVYKKLKEGSDKFV----AKGLVRSAQGKEKIGGEADVFIGDITDA 60 Query: 73 QELSALADFAISKLGKVDILV 93 ++ +D LV Sbjct: 61 DSINPAFQ-------GIDALV 74 >4KDR-A nrPDB Length = 223 Score = 34.8 bits (79), Expect = 0.040, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 31/84 (36%), Gaps = 12/84 (14%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 L GK + G G GI +A + A GA+V D+ + + G Q + Sbjct: 61 LFGKKVLDVGCGGGI---LAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQ-- 115 Query: 69 ITSEQELSALADFAISKLGKVDIL 92 + + A G+ D++ Sbjct: 116 -------ETVEEHAAKHAGQYDVV 132 >4A10-A nrPDB Length = 447 Score = 34.8 bits (79), Expect = 0.041, Method: Composition-based stats. Identities = 30/141 (21%), Positives = 50/141 (35%), Gaps = 19/141 (13%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDI 69 G +I GA G+G AI F G + V+ +++ V + LG R ++ Sbjct: 220 QGDIVLIWGASGGLG-SYAIQFVKNGGGIPVAVVSSAQKEAAV---RALGCDLVINRAEL 275 Query: 70 TSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLV 129 +++ + K+ LV G P +E F LS +V Sbjct: 276 GITDDIADDPRRVVETGRKLAKLVVEKAGREP----------DIVFEHTGRVTFGLSVIV 325 Query: 130 APEMEKNGGGVILTITSMAAE 150 A GG ++T S + Sbjct: 326 A-----RRGGTVVTCGSSSGY 341 >3A14-A nrPDB Length = 376 Score = 34.8 bits (79), Expect = 0.041, Method: Composition-based stats. Identities = 22/137 (16%), Positives = 48/137 (35%), Gaps = 10/137 (7%) Query: 9 LDGKCAIITGAGAGIGKEIAITFAT-AGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 ++ + +I GA IG + G ++ ++ +++ + A Sbjct: 1 MEERTLVILGATGSIGTQTLDVLKKVKGIRLIGISFHS-NLELAFKIVKEFNVKNVAITG 59 Query: 68 DITSEQELSAL------ADFAISKLGKVDI-LVNNAGGGGPKPFDMPMADFRRAYELNVF 120 D+ E + + + L K DI +V +G G + + +R N Sbjct: 60 DVEFEDSSINVWKGSHSIEEMLEAL-KPDITMVAVSGFSGLRAVLASLEHSKRVCLANKE 118 Query: 121 SFFHLSQLVAPEMEKNG 137 S LV ++++ G Sbjct: 119 SLVCGGFLVKKKLKEKG 135 >6C6P-A nrPDB Length = 458 Score = 34.4 bits (78), Expect = 0.044, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 29/73 (39%), Gaps = 3/73 (4%) Query: 14 AIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQ 73 II GAG +G +A + G V V + + + +V E Q GG + D+ Sbjct: 10 VIIVGAGV-LGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQPGG--YHVLKDLGLGD 66 Query: 74 ELSALADFAISKL 86 + L ++ Sbjct: 67 TVEGLDAQVVNGY 79 >3PVZ-A nrPDB Length = 399 Score = 34.4 bits (78), Expect = 0.044, Method: Composition-based stats. Identities = 38/227 (16%), Positives = 70/227 (30%), Gaps = 32/227 (14%) Query: 15 IITGAGAGIGKEIAIT-FATAGASVVVSDINADAANHVVDEIQQL----GGQAFACRCDI 69 ++ G IG+ + F + V DI+ + +V +I+ G DI Sbjct: 39 LVLGGAGSIGQAVTKEIFKRNPQKLHVVDISENNMVELVRDIRSSFGYINGDFQTFALDI 98 Query: 70 TSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLV 129 S + D I G+ D V N + R ++NVF+ Q Sbjct: 99 GSIE-----YDAFIKADGQYDY-VLNLSALKHVRSEKDPFTLMRMIDVNVFNTDKTIQQS 152 Query: 130 APEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAP 189 G +++ A N + +SK + + ++ R +A Sbjct: 153 I----DAGAKKYFCVSTDKAANP---VNMMGASKRIMEMFLMRKSEEIAISTARFANVA- 204 Query: 190 GAILTDALKSVITPEIEQKMLQHTPI-------RRLGQPQDIANAAL 229 + Q++ ++ PI R PQ+ L Sbjct: 205 ------FSDGSLLHGFNQRIQKNQPIVAPNDIKRYFVTPQESGELCL 245 >3NJ4-A nrPDB Length = 435 Score = 34.4 bits (78), Expect = 0.044, Method: Composition-based stats. Identities = 26/139 (18%), Positives = 52/139 (37%), Gaps = 13/139 (9%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR--- 66 GK A++ G G +GK A GA V++++I+ A E ++ AC+ Sbjct: 215 AGKVAVVAGYGD-VGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGN 273 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLS 126 +T+ + + ++ K D +V N G + D+ + ++N Sbjct: 274 IFVTTTGCIDIILGRHFEQM-KDDAIVCNIGHFDVE-IDVKWLNENAVEKVN-------I 324 Query: 127 QLVAPEMEKNGGGVILTIT 145 + G I+ + Sbjct: 325 KPQVDRYRLKNGRRIILLA 343 >4KDC-A nrPDB Length = 246 Score = 34.4 bits (78), Expect = 0.045, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 31/84 (36%), Gaps = 12/84 (14%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 L GK + G G GI +A + A GA+V D+ + + G Q + Sbjct: 61 LFGKKVLDVGCGGGI---LAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQ-- 115 Query: 69 ITSEQELSALADFAISKLGKVDIL 92 + + A G+ D++ Sbjct: 116 -------ETVEEHAAKHAGQYDVV 132 >1GPJ-A nrPDB Length = 404 Score = 34.0 bits (77), Expect = 0.062, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 34/94 (36%), Gaps = 17/94 (18%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 L K ++ GAG +GK +A + G V+ V+ + LGG+A Sbjct: 164 SLHDKTVLVVGAGE-MGKTVAKSLVDRGVRAVLVA--NRTYERAVELARDLGGEAVR--- 217 Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGP 101 D + L + D++V+ P Sbjct: 218 -----------FDELVDHLARSDVVVSATAAPHP 240 >1RPN-A nrPDB Length = 335 Score = 33.6 bits (76), Expect = 0.081, Method: Composition-based stats. Identities = 13/76 (17%), Positives = 26/76 (34%), Gaps = 4/76 (5%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLG--GQAFACRCDI 69 + A++TG G +A G V + A ++ +++LG G D+ Sbjct: 15 RSALVTGITGQDGAYLAKLLLEKGYRV--HGLVARRSSDTRWRLRELGIEGDIQYEDGDM 72 Query: 70 TSEQELSALADFAISK 85 + A + Sbjct: 73 ADACSVQRAVIKAQPQ 88 >2C54-A nrPDB Length = 379 Score = 33.6 bits (76), Expect = 0.090, Method: Composition-based stats. Identities = 21/114 (18%), Positives = 34/114 (29%), Gaps = 15/114 (13%) Query: 16 ITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQEL 75 ITGAG I IA G V+ SD + + + + D+ Sbjct: 34 ITGAGGFIASHIARRLKHEGHYVIASDWKKN------EHMTEDMFCDEFHLVDL------ 81 Query: 76 SALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLV 129 + + + VD + N A G F N F++ + Sbjct: 82 -RVMENCLKVTEGVDHVFNLAADMGGMGFIQSNHSV--IMYNNTMISFNMIEAA 132 >2C20-A nrPDB Length = 330 Score = 33.2 bits (75), Expect = 0.097, Method: Composition-based stats. Identities = 33/171 (19%), Positives = 55/171 (32%), Gaps = 37/171 (21%) Query: 14 AIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG---QAFACRCDIT 70 +I G IG G SVVV D + E + + A D+ Sbjct: 4 ILICGGAGYIGSHAVKKLVDEGLSVVVVDNLQTGHEDAITEGAKFYNGDLRDKAFLRDVF 63 Query: 71 SEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLVA 130 +++ + A+ FA D LV G KP + Y NV+ L Sbjct: 64 TQENIEAVMHFAA------DSLV---GVSMEKPL--------QYYNNNVYGALCL----L 102 Query: 131 PEMEKNGGGVILTITSMAAENKNINM------------TSYASSKAAASHL 169 M++ + +S AA +++ +Y +K A + Sbjct: 103 EVMDEFKVDKFIF-SSTAATYGEVDVDLITEETMTNPTNTYGETKLAIEKM 152 >3CT4-A nrPDB Length = 332 Score = 33.2 bits (75), Expect = 0.100, Method: Composition-based stats. Identities = 20/99 (20%), Positives = 38/99 (38%), Gaps = 14/99 (14%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAG---ASV---VVSDINADAANHVVDEIQQLGGQAF 63 GK A+++G G+G A F G A+V + + D + + G Sbjct: 45 SGKVALVSGGGSGHEPAHA-GFVGEGMLSAAVCGAIFTSPTPDQIYEAIKSADEGAGVLL 103 Query: 64 ACR---CDITSEQELSALADFAISKLGKV----DILVNN 95 + D+ + + +A+ K+ ++ DI V N Sbjct: 104 IIKNYLGDVMNFEMAREMAEMEEIKVEQIIVDDDIAVEN 142 >1O89-A nrPDB Length = 345 Score = 33.2 bits (75), Expect = 0.10, Method: Composition-based stats. Identities = 10/48 (20%), Positives = 16/48 (33%), Gaps = 4/48 (8%) Query: 14 AIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQ 61 ++TGA G+G G VV + ++ LG Sbjct: 171 IVVTGASGGVGSTAVALLHKLGYQVVAVS----GRESTHEYLKSLGAS 214 >3X2F-A nrPDB Length = 411 Score = 33.2 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 31/188 (16%), Positives = 67/188 (35%), Gaps = 30/188 (15%) Query: 4 SDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINA-DAANHVVDEIQQLGGQA 62 ++ L+ K A +AIT + GA VV++ N + V + ++ G Sbjct: 38 GMSIHLEAKTAY-----------LAITLSKLGAKVVITGSNPLSTQDDVAEALRSKGITV 86 Query: 63 FACRCDITSEQEL--SALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVF 120 +A R T ++ + L + D ++++ GG + N+ Sbjct: 87 YARR---THDESIYRENLMKVLDE---RPDFIIDD-GGDLTVISHTEREEVLE----NLK 135 Query: 121 SF----FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFD 176 + +E+ G + I ++ K + Y + ++ ++RN Sbjct: 136 GVSEETTTGVRR-LKALEETGKLRVPVIAVNDSKMKYLFDNRYGTGQSTWDAIMRNTNLL 194 Query: 177 LGEKNIRV 184 + KN+ V Sbjct: 195 VAGKNVVV 202 Score = 32.5 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 22/95 (23%), Positives = 44/95 (46%), Gaps = 14/95 (14%) Query: 1 MFNSDNLRLDGKCAIITGAGAG-IGKEIAITFATAGASVVVSDINADAANHVV------- 52 + + NL + GK ++ AG G G+ IA+ A GA V+V++++ A + Sbjct: 187 IMRNTNLLVAGKNVVV--AGYGWCGRGIALRAAGLGARVIVTEVDPVKAVEAIMDGFTVM 244 Query: 53 --DEIQQLGGQAFACRC--DITSEQELSALADFAI 83 E ++ D+ S++++ +L D A+ Sbjct: 245 PMKEAVKIADFVITASGNTDVLSKEDILSLKDGAV 279 >4BKP-A nrPDB Length = 336 Score = 32.9 bits (74), Expect = 0.13, Method: Composition-based stats. Identities = 21/131 (16%), Positives = 42/131 (32%), Gaps = 35/131 (26%) Query: 4 SDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAF 63 ++NL ++TG +GK I VV + L G+ + Sbjct: 15 TENLYFQSMRILVTGGSGLVGKAI---------------------QKVVADGAGLPGEDW 53 Query: 64 ACR----CDITSEQELSALADFAISKLGKVDILVNNAGGGGP--KPFDMPMADFRRAYEL 117 D+T + AL + +++ A G + + +R+ + Sbjct: 54 VFVSSKDADLTDTAQTRALFEKVQPTH-----VIHLAAMVGGLFRNIKYNLDFWRKNVHM 108 Query: 118 N---VFSFFHL 125 N + S F + Sbjct: 109 NDNVLHSAFEV 119 >1VPD-A nrPDB Length = 299 Score = 32.9 bits (74), Expect = 0.14, Method: Composition-based stats. Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 8/69 (11%) Query: 4 SDNLRLDGKCAIITGAGAGI-GKEIAITFATAGASVVVSDINADAANHVVDEIQQLG--G 60 S+ + + K I G GI GK ++ AG S+VVSD N +A V+ + Sbjct: 1 SNAMTM--KVGFI---GLGIMGKPMSKNLLKAGYSLVVSDRNPEAIADVIAAGAETASTA 55 Query: 61 QAFACRCDI 69 +A A +CD+ Sbjct: 56 KAIAEQCDV 64 >3R0Q-C nrPDB Length = 376 Score = 32.9 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 31/84 (36%), Gaps = 8/84 (9%) Query: 3 NSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQA 62 + +GK + G G+GI +AI A AGA V + A+H ++ Sbjct: 56 FQNKHHFEGKTVLDVGTGSGI---LAIWSAQAGARKVYAVEATKMADHARALVKANNLDH 112 Query: 63 FACRC-----DITSEQELSALADF 81 DI+ +++ + Sbjct: 113 IVEVIEGSVEDISLPEKVDVIISE 136 >3K30-A nrPDB Length = 690 Score = 32.5 bits (73), Expect = 0.16, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 19/50 (38%), Gaps = 1/50 (2%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQA 62 ++ GAG G E A G VV+++ D V E G A Sbjct: 393 RVLVVGAGPS-GLEAARALGVRGYDVVLAEAGRDLGGRVTQESALPGLSA 441 >3N58-A nrPDB Length = 464 Score = 32.5 bits (73), Expect = 0.17, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 28/67 (41%), Gaps = 6/67 (8%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 + GK A++ G G +GK A + A AGA V V+ + + + G D Sbjct: 245 MAGKVAVVCGYGD-VGKGSAQSLAGAGARVKVT-----EVDPICALQAAMDGFEVVTLDD 298 Query: 69 ITSEQEL 75 S ++ Sbjct: 299 AASTADI 305 >4G2N-A nrPDB Length = 345 Score = 32.5 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 21/48 (43%), Gaps = 3/48 (6%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDE 54 + L G+ I G G IG+ IA G + + N +H ++E Sbjct: 169 MGLTGRRLGIFGMGR-IGRAIATR--ARGFGLAIHYHNRTRLSHALEE 213 >2VN8-A nrPDB Length = 375 Score = 32.5 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 20/116 (17%), Positives = 41/116 (35%), Gaps = 13/116 (11%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDI 69 GK +I GA G+G A V + + + A+ +V ++ D+ Sbjct: 183 TGKRVLILGASGGVGTFAIQVMKAWDAHV--TAVCSQDASELVRKLGAD---------DV 231 Query: 70 TSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHL 125 + + + L D +++N GG + + A + + + F L Sbjct: 232 IDYKS--GSVEEQLKSLKPFDFILDNVGGSTETWAPDFLKKWSGATYVTLVTPFLL 285 >3HZZ-A nrPDB Length = 467 Score = 32.5 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 29/151 (19%), Positives = 45/151 (29%), Gaps = 37/151 (24%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGAS----VVVSDINADAANHV-VDEIQQLGGQAFA 64 G +I GA G+G A FA AG + VV S A+ + + I + + Sbjct: 246 QGDNVLIWGASGGLG-SYATQFALAGGANPICVVSSPQKAEICRSMGAEAIIDRNAEGYK 304 Query: 65 CRCD--ITSEQELSALADFAISKLGK--VDILVNNAGGGGPKPFDMPMADFRRAYELNVF 120 D +E G +DI+ + G R + +V+ Sbjct: 305 FWKDEHTQDPKEWKRFGKRIRELTGGEDIDIVFEHPG--------------RETFGASVY 350 Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAEN 151 GG I T S + Sbjct: 351 VT-------------RKGGTITTCASTSGYM 368 >5UZH-A nrPDB Length = 345 Score = 32.5 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 24/77 (31%), Gaps = 5/77 (6%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVV-----SDINADAANHVVDEIQQLGGQAFACR 66 K A+ITG G +A G V S N H+ +I + Sbjct: 2 KVALITGITGQDGSYLAEFLLEKGYMVYGIIRRSSSFNTGRVEHLYKDIHITKAKFKLLY 61 Query: 67 CDITSEQELSALADFAI 83 D+T L ++ Sbjct: 62 GDLTDTGNLISIIAKIK 78 >5ENV-A nrPDB Length = 347 Score = 32.5 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 40/93 (43%), Gaps = 11/93 (11%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATA-GASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 + G I+GA G+G +A+ +A A G V + D + + +GG+ F Sbjct: 168 MAGHWVAISGAAGGLG-SLAVQYAKAMGYRV----LGIDGGEGKEELFRSIGGEVFI--- 219 Query: 68 DITSEQELSALADFAIS--KLGKVDILVNNAGG 98 D T E+++ A G +++ V+ A Sbjct: 220 DFTKEKDIVGAVLKATDGGAHGVINVSVSEAAI 252 >4PZE-A nrPDB Length = 284 Score = 32.1 bits (72), Expect = 0.23, Method: Composition-based stats. Identities = 39/195 (20%), Positives = 65/195 (33%), Gaps = 24/195 (12%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITS 71 + I GAG +G IA A G +VV+ DI+ A V + + + +T Sbjct: 4 RTVGIVGAGT-MGNGIAQACAVVGLNVVMVDISDAAVQKGVATVASSLDR-LIKKEKLTE 61 Query: 72 EQELSALAD----FAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNV-----FSF 122 + SALA + L DI++ A + + NV S Sbjct: 62 ADKASALARIKGSTSYDDLKATDIVIEAATENYDLKVKI-LKQIDGIVGENVIIASNTSS 120 Query: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKA-----AASHLVRNMAFDL 177 +++L A + + M N M + V ++ L Sbjct: 121 ISITKLAA---VTSRADRFI---GMHFFNPVPVMALVELIRGLQTSDTTHAAVEALSKQL 174 Query: 178 GEKNIRVNGIAPGAI 192 G+ I V +PG + Sbjct: 175 GKYPITVKN-SPGFV 188 >6BI4-A nrPDB Length = 346 Score = 32.1 bits (72), Expect = 0.23, Method: Composition-based stats. Identities = 30/180 (16%), Positives = 58/180 (32%), Gaps = 25/180 (13%) Query: 2 FNSDNLRLDGKCAIITGAGAGIGKEIAITFAT--AGASVV-VSDINADAANHVVDEIQQL 58 F S+ + ++TG IG ++ + + V IQ Sbjct: 20 FQSNAMN-----ILVTGGAGFIGSNFVHYMLQSYETYKIINFDALTYSGNLNNVKSIQDH 74 Query: 59 GGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELN 118 + + +I + + L + + ++VN A D + + Y+ N Sbjct: 75 -PNYYFVKGEIQNGELLEHVIKERDVQ-----VIVNFAAESH---VDRSIENPIPFYDTN 125 Query: 119 VFSFFHLSQLV--APEME------KNGGGVILTITSMAAENKNINMTSYASSKAAASHLV 170 V L +LV P ++ G + E + Y+SSKA+A + Sbjct: 126 VIGTVTLLELVKKYPHIKLVQVSTDEVYGSLGKTGRFTEETPLAPNSPYSSSKASADMIA 185 >5A3V-A nrPDB Length = 329 Score = 32.1 bits (72), Expect = 0.23, Method: Composition-based stats. Identities = 25/121 (20%), Positives = 49/121 (40%), Gaps = 16/121 (13%) Query: 1 MFNSDNLRLDG--KCA--IITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQ 56 + N L+LDG K A ++T A G+G +A A + + + A ++ ++ Sbjct: 142 LTNPAGLKLDGTGKKANILVTAASGGVG-----HYAVQLAKLANAHVTATCGARNIEFVK 196 Query: 57 QLGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYE 116 LG D + + A K K D +V+ A G F+ +++ + + Sbjct: 197 SLGADEV---LDYKTPEG--AALKSPSGK--KYDAVVHCANGIPFSVFEPNLSENGKVID 249 Query: 117 L 117 + Sbjct: 250 I 250 >4J90-A nrPDB Length = 222 Score = 32.1 bits (72), Expect = 0.24, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 24/71 (33%), Gaps = 7/71 (9%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 R+ K + G G G I G V+ DIN + N A Sbjct: 3 RIKNKQFAVIGLGR-FGGSICKELHRMGHEVLAVDINEEKVNAYASYAT------HAVIA 55 Query: 68 DITSEQELSAL 78 + T E EL +L Sbjct: 56 NATEENELLSL 66 >3PEF-A nrPDB Length = 287 Score = 32.1 bits (72), Expect = 0.24, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 23/47 (48%), Gaps = 4/47 (8%) Query: 23 IGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDI 69 +G +A AG SV + + + + A +E+ LG + A C++ Sbjct: 12 MGSAMAKNLVKAGCSVTIWNRSPEKA----EELAALGAERAATPCEV 54 >3DFZ-A nrPDB Length = 223 Score = 32.1 bits (72), Expect = 0.24, Method: Composition-based stats. Identities = 21/110 (19%), Positives = 36/110 (32%), Gaps = 7/110 (6%) Query: 6 NLRLDGKCAIITGAGAGIGKEIAITFATAGASV------VVSDINADAANHVVDEIQQLG 59 L L G+ ++ G G I F GA++ V ++IN A + ++ Sbjct: 26 MLDLKGRSVLVVGGGT-IATRRIKGFLQEGAAITVVAPTVSAEINEWEAKGQLRVKRKKV 84 Query: 60 GQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMA 109 G+ + + + K D LVN A +P Sbjct: 85 GEEDLLNVFFIVVATNDQAVNKFVKQHIKNDQLVNMASSFSDGNIQIPAQ 134 >6GBN-A nrPDB Length = 438 Score = 32.1 bits (72), Expect = 0.27, Method: Composition-based stats. Identities = 14/36 (38%), Positives = 23/36 (63%), Gaps = 1/36 (2%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN 44 + GK A++ G G +GK A + AGA V+V++I+ Sbjct: 217 MAGKVAVVAGYGD-VGKGSAASLRGAGARVIVTEID 251 >2EER-A nrPDB Length = 347 Score = 32.1 bits (72), Expect = 0.27, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 22/42 (52%), Gaps = 1/42 (2%) Query: 12 KCAIITGAGAGIGK-EIAITFATAGASVVVSDINADAANHVV 52 K ++ GAG G+G I I A +GA+++ D+ +A Sbjct: 172 KTLVVIGAGGGLGTMAIQIAKAVSGATIIGVDVREEALEAAK 213 >4B4V-A nrPDB Length = 303 Score = 31.7 bits (71), Expect = 0.30, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 26/55 (47%) Query: 1 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEI 55 + +N+ + GK A++ G A +GK +A+ A A+V + +V + Sbjct: 169 ILKENNIEIAGKHAVVVGRSAILGKPMAMMLLQANATVTICHSRTQNLPELVKQA 223 >3DMF-A nrPDB Length = 381 Score = 31.7 bits (71), Expect = 0.32, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 36/85 (42%), Gaps = 13/85 (15%) Query: 11 GKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDIT 70 G+ + GAG G + + A GA VV + + + + ++ +A A D+ Sbjct: 234 GRQVLDLGAGYG---ALTLPLARMGAEVVGVEDDLASVLSLQKGLEANALKAQALHSDV- 289 Query: 71 SEQELSALADFAISKLGKVDILVNN 95 D A+++ + DI+V N Sbjct: 290 ---------DEALTEEARFDIIVTN 305 >2X86-A nrPDB Length = 357 Score = 31.7 bits (71), Expect = 0.33, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 28/85 (32%), Gaps = 12/85 (14%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITS 71 + I+TG IG I G ++DI VVD ++ +I Sbjct: 47 RMIIVTGGAGFIGSNIVKALNDKG----ITDI------LVVDNLKDGTKFVNLVDLNIAD 96 Query: 72 EQELSALADFAI--SKLGKVDILVN 94 + + + G V+ + + Sbjct: 97 YMDKEDFLIQIMAGEEFGDVEAIFH 121 >6C55-A nrPDB Length = 340 Score = 31.3 bits (70), Expect = 0.37, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 23/62 (37%), Gaps = 2/62 (3%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFAC-RC 67 L GK + G G+ G A G VV+ + + ++ + A A + Sbjct: 15 LQGKKIAVVGYGS-QGHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPVAEAVKQA 73 Query: 68 DI 69 D+ Sbjct: 74 DV 75 >3WMX-A nrPDB Length = 358 Score = 31.3 bits (70), Expect = 0.38, Method: Composition-based stats. Identities = 36/203 (17%), Positives = 63/203 (31%), Gaps = 39/203 (19%) Query: 4 SDNLRLDGKCAIITGAGAGIGKEIAITFATA-GASVVVSDINADAANHVVDEIQQLGGQA 62 ++ +I GA IG E+A+ A G + V++ HV Sbjct: 18 GSHMEAGKPKILIVGANGQIGSELALALAERYGRTNVITSDVVPTGRHV---------HL 68 Query: 63 FACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSF 122 + T EL+ + + + G + + A + A+ LN+ S Sbjct: 69 THEMLNATDRGELATVVE----RHGITQVYLLAAALSATGE---KAPQW--AWNLNMTSL 119 Query: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENK------------NINMTSYASSKAAASHLV 170 ++ +L + G + +S+AA T Y SK A Sbjct: 120 LNVLELA----RQTGLERVFWPSSIAAFGPTTPAGQTPQKTVMEPTTVYGISKQAGEGWC 175 Query: 171 RNMAFDLGEKNIRVNGIA-PGAI 192 R + V + PG I Sbjct: 176 RWY---HANHGVDVRSVRYPGLI 195 >3K96-A nrPDB Length = 356 Score = 31.3 bits (70), Expect = 0.41, Method: Composition-based stats. Identities = 23/93 (24%), Positives = 34/93 (36%), Gaps = 8/93 (8%) Query: 2 FNSDNLR-LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG 60 F S+ + AI+ G +A+ A G V + +D VDE+Q G Sbjct: 20 FQSNAMEPFKHPIAIL--GAGSWGTALALVLARKGQKVRLWSYESDH----VDEMQAEGV 73 Query: 61 QAFACRCDITSEQELSALADFAISKLGKVDILV 93 + + L A D S G DIL+ Sbjct: 74 NNRYLP-NYPFPETLKAYCDLKASLEGVTDILI 105 >4EJ6-A nrPDB Length = 370 Score = 31.3 bits (70), Expect = 0.42, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 31/90 (34%), Gaps = 7/90 (7%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDI 69 G I G G IG AGA+ V+ + +E+ D Sbjct: 182 AGSTVAILGGGV-IGLLTVQLARLAGATTVILSTRQATKRRLAEEVGA------TATVDP 234 Query: 70 TSEQELSALADFAISKLGKVDILVNNAGGG 99 ++ + A+A G VD+++ AG Sbjct: 235 SAGDVVEAIAGPVGLVPGGVDVVIECAGVA 264 >1JAY-A nrPDB Length = 212 Score = 31.3 bits (70), Expect = 0.46, Method: Composition-based stats. Identities = 14/51 (27%), Positives = 25/51 (49%), Gaps = 1/51 (1%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQA 62 + A++ G +GK +A+ AT G +VV + A E +++ G A Sbjct: 2 RVALL-GGTGNLGKGLALRLATLGHEIVVGSRREEKAEAKAAEYRRIAGDA 51 >5F5N-A nrPDB Length = 289 Score = 30.9 bits (69), Expect = 0.48, Method: Composition-based stats. Identities = 9/72 (12%), Positives = 15/72 (20%), Gaps = 4/72 (5%) Query: 11 GKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDIT 70 + ++TGA G G V + D+ Sbjct: 1 NRTILVTGATGTQGGATVRALLARGRPVRALVRDP----GTDAARALAAAGVSLVTGDLN 56 Query: 71 SEQELSALADFA 82 + L A Sbjct: 57 DQASLRAAMADV 68 >4B4O-A nrPDB Length = 298 Score = 30.9 bits (69), Expect = 0.53, Method: Composition-based stats. Identities = 9/60 (15%), Positives = 17/60 (28%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSE 72 ++ G IG + G V + DE+ G + ++ E Sbjct: 2 RVLVGGGTGFIGTALTQLLNARGHEVTLVSRKPGPGRITWDELAASGLPSCDAAVNLAGE 61 >4B3J-A nrPDB Length = 736 Score = 30.9 bits (69), Expect = 0.53, Method: Composition-based stats. Identities = 23/110 (20%), Positives = 39/110 (35%), Gaps = 26/110 (23%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQA--------- 62 K + GAG +G IA A AG VV+ D++ +AA ++L +A Sbjct: 342 KRIGVLGAGM-MGAGIAYVSAKAGYEVVLKDVSLEAAAKGKGYSEKLEAKALERGRTTQE 400 Query: 63 --------FACRCDITSEQELSALADFAISK-------LGKV-DILVNNA 96 D + + + + G++ DI+ NA Sbjct: 401 RSDALLARITPTADAADFKGVDFVIEAVFENQELKHKVFGEIEDIVEPNA 450 >1IE3-A nrPDB Length = 312 Score = 30.9 bits (69), Expect = 0.53, Method: Composition-based stats. Identities = 31/162 (19%), Positives = 52/162 (32%), Gaps = 31/162 (19%) Query: 12 KCAIITGAGAGIGKEIAITFATA---GASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 K A + GA GIG+ +A+ T G+ + + DI D Sbjct: 2 KVA-VLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTP---------------GVAVD 45 Query: 69 ITSEQELSALA----DFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFH 124 ++ + + A L D+++ +AG D + +N + Sbjct: 46 LSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRS-----DLFNVNAGIVKN 100 Query: 125 LSQLVAPEMEKNGGGVI---LTITSMAAENKNINMTSYASSK 163 L Q VA K G+I + T A Y +K Sbjct: 101 LVQQVAKTCPKACIGIITNPVNTTVAIAAEVLKKAGVYDKNK 142 >1EQ2-A nrPDB Length = 310 Score = 30.9 bits (69), Expect = 0.56, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 27/83 (32%), Gaps = 12/83 (14%) Query: 14 AIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQ 73 I+TG IG I G ++DI VVD ++ +I Sbjct: 2 IIVTGGAGFIGSNIVKALNDKG----ITDI------LVVDNLKDGTKFVNLVDLNIADYM 51 Query: 74 ELSALADFAI--SKLGKVDILVN 94 + + + G V+ + + Sbjct: 52 DKEDFLIQIMAGEEFGDVEAIFH 74 >3HDH-A nrPDB Length = 302 Score = 30.9 bits (69), Expect = 0.58, Method: Composition-based stats. Identities = 13/51 (25%), Positives = 20/51 (39%), Gaps = 1/51 (1%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQA 62 K + G G +G IA A G +VV+ D D I++ + Sbjct: 16 KHVTVIGGGL-MGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKV 65 >5TC4-A nrPDB Length = 316 Score = 30.9 bits (69), Expect = 0.60, Method: Composition-based stats. Identities = 18/107 (16%), Positives = 30/107 (28%), Gaps = 25/107 (23%) Query: 11 GKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDIT 70 GK ++ G +G IA+ T GA ++ GG A Sbjct: 159 GKNVVVAGRSKNVGMPIAMLLHTDGAH------------------ERPGGDATVT----- 195 Query: 71 SEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYEL 117 + DI+++ AG DM ++ Sbjct: 196 -ISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEG-AAVIDV 240 >5JE5-A nrPDB Length = 247 Score = 30.9 bits (69), Expect = 0.61, Method: Composition-based stats. Identities = 23/89 (25%), Positives = 34/89 (38%), Gaps = 16/89 (17%) Query: 9 LDGKCAIITGAGAGI-GKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 + GK + G G G+EI A A VV DI+ +E ++ G Sbjct: 40 VSGKSVLDLACGFGFFGREIYRRGA---AKVVGVDISEKMIELAREESRKYGDPLEFHVR 96 Query: 68 DITSEQELSALADFAISKLGKVDILVNNA 96 D+ + + LG+ D LVN A Sbjct: 97 DVANMEP-----------LGQFD-LVNAA 113 >1QQV-A nrPDB Length = 67 Score = 30.5 bits (68), Expect = 0.62, Method: Composition-based stats. Identities = 9/53 (16%), Positives = 22/53 (41%), Gaps = 4/53 (7%) Query: 88 KVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLV---APEMEKNG 137 +D+LVN A P+ D + + + + + F +++ P ++ Sbjct: 8 PLDVLVNTAAEDLPRGVDPSRKENHLS-DEDFKAVFGMTRSAFANLPLWKQQN 59 >1F14-A nrPDB Length = 310 Score = 30.5 bits (68), Expect = 0.62, Method: Composition-based stats. Identities = 13/51 (25%), Positives = 20/51 (39%), Gaps = 1/51 (1%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQA 62 K + G G +G IA A G +VV+ D D I++ + Sbjct: 16 KHVTVIGGGL-MGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKV 65 >5BUT-A nrPDB Length = 288 Score = 30.5 bits (68), Expect = 0.69, Method: Composition-based stats. Identities = 12/43 (27%), Positives = 16/43 (37%), Gaps = 1/43 (2%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANH 50 R+ K + G G G I G V+ DIN + N Sbjct: 3 RIKNKQFAVIGLGR-FGGSIVKELHRMGHEVLAVDINEEKVNA 44 Score = 29.4 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 13/43 (30%), Positives = 17/43 (39%), Gaps = 2/43 (4%) Query: 9 LDG-KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANH 50 L+G K + G G G I G V+ DIN + N Sbjct: 145 LEGSKQFAVIGLGR-FGGSIVKELHRMGHEVLAVDINEEKVNA 186 >2HK7-A nrPDB Length = 269 Score = 30.5 bits (68), Expect = 0.70, Method: Composition-based stats. Identities = 10/64 (15%), Positives = 25/64 (39%), Gaps = 4/64 (6%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITS 71 K ++ GAG G + + GA V + + + A + Q+ + ++ Sbjct: 124 KSILVLGAG-GASRAVIYALVKEGAKVFLWNRTKEKA---IKLAQKFPLEVVNSPEEVID 179 Query: 72 EQEL 75 + ++ Sbjct: 180 KVQV 183 >1V8B-A nrPDB Length = 479 Score = 30.5 bits (68), Expect = 0.70, Method: Composition-based stats. Identities = 31/158 (19%), Positives = 57/158 (36%), Gaps = 32/158 (20%) Query: 1 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG 60 + + + + GK +I G G +GK A + GA V +++I+ A V E G Sbjct: 247 LMRATDFLISGKIVVICGYGD-VGKGCASSMKGLGARVYITEIDPICAIQAVME----GF 301 Query: 61 QAFACRCDITSEQELSALADFAISKLGKVDI-------------LVNNAGGGGPKPFDMP 107 E+ DF I+ G VD+ +V N G + Sbjct: 302 NVVTL-------DEIVDKGDFFITCTGNVDVIKLEHLLKMKNNAVVGNIGHFDDEIQVNE 354 Query: 108 MADFRRAYELNVFSFFHLSQLVAPEMEKNGGGVILTIT 145 + +++ + NV + ++ P G I+ + Sbjct: 355 LFNYKGIHIENVK--PQVDRITLP-----NGNKIIVLA 385 >2OHJ-A nrPDB Length = 404 Score = 30.5 bits (68), Expect = 0.72, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 20/49 (40%) Query: 18 GAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 G+ + IA + G V V ++ D + +V +I + G A Sbjct: 268 GSTRKMAHAIAEGAMSEGVDVRVYCLHEDDRSEIVKDILESGAIALGAP 316 >3BIC-A nrPDB Length = 762 Score = 30.5 bits (68), Expect = 0.72, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 30/92 (32%), Gaps = 2/92 (2%) Query: 18 GAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQELSA 77 G G K IA FA G V + + V + A + L Sbjct: 616 GHDRG-AKVIATGFADLGFDVDIGPL-FQTPREVAQQAVDADVHAVGVSTLAAGHKTLVP 673 Query: 78 LADFAISKLGKVDILVNNAGGGGPKPFDMPMA 109 ++ LG+ DILV G P+ ++ Sbjct: 674 ELIKELNSLGRPDILVMCGGVIPPQDYEFLFE 705 >2HMT-A nrPDB Length = 144 Score = 30.5 bits (68), Expect = 0.73, Method: Composition-based stats. Identities = 12/43 (27%), Positives = 16/43 (37%), Gaps = 1/43 (2%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANH 50 R+ K + G G G I G V+ DIN + N Sbjct: 3 RIKNKQFAVIGLGR-FGGSIVKELHRMGHEVLAVDINEEKVNA 44 >4E0B-A nrPDB Length = 313 Score = 30.5 bits (68), Expect = 0.79, Method: Composition-based stats. Identities = 13/35 (37%), Positives = 20/35 (57%), Gaps = 4/35 (11%) Query: 12 KCAIITGAGAGIGKEIAITFAT---AGASVVVSDI 43 K A+I GA GIG+ +A+ AG+ + + DI Sbjct: 5 KVAVI-GAAGGIGQALALLLKNRLPAGSDLALYDI 38 >3ZU2-A nrPDB Length = 422 Score = 30.2 bits (67), Expect = 0.91, Method: Composition-based stats. Identities = 20/129 (15%), Positives = 34/129 (26%), Gaps = 19/129 (14%) Query: 12 KCAIITGAGAGIGKE----IAITFATAGASVVVSDINADA---------ANHVVDEIQQL 58 K ++ GA G G A V + + Q Sbjct: 65 KRVLVIGASTGYGLAARITAAFGCGADTLGVFFERPGEEGKPGTSGWYNSAAFHKFAAQK 124 Query: 59 GGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAY--- 115 G A + D S++ D LG+VD ++ + + F A Sbjct: 125 GLYAKSINGDAFSDEIKQLTIDAIKQDLGQVDQVIYSLASPR-RTHPKTGEVFNSALKPI 183 Query: 116 --ELNVFSF 122 +N+ Sbjct: 184 GNAVNLRGL 192 >5U9C-A nrPDB Length = 292 Score = 30.2 bits (67), Expect = 0.99, Method: Composition-based stats. Identities = 8/41 (19%), Positives = 19/41 (46%), Gaps = 3/41 (7%) Query: 4 SDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN 44 S+ ++ + +ITG +G + +V+V++ N Sbjct: 1 SNAMK---RKILITGGTGMLGAYVTSALKDTDYNVIVTERN 38 >4A5O-A nrPDB Length = 286 Score = 30.2 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 15/52 (28%), Positives = 25/52 (48%), Gaps = 1/52 (1%) Query: 1 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDI-NADAANHV 51 + S L G A++ GA +G+ +A+ G +V V+ D A+HV Sbjct: 151 LLASTGADLYGMDAVVVGASNIVGRPMALELLLGGCTVTVTHRFTRDLADHV 202 >7REQ-A nrPDB Length = 727 Score = 29.8 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 30/88 (34%), Gaps = 9/88 (10%) Query: 27 IAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQ----ELSALADFA 82 IA +A G V + +E + +A ++S L Sbjct: 616 IATAYADLGFDV-----DVGPLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPALRKE 670 Query: 83 ISKLGKVDILVNNAGGGGPKPFDMPMAD 110 + KLG+ DIL+ G + FD D Sbjct: 671 LDKLGRPDILITVGGVIPEQDFDELRKD 698 >1ZDL-A nrPDB Length = 517 Score = 29.8 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 15/38 (39%), Gaps = 1/38 (2%) Query: 15 IITGAGAGIGKEIAITFATAGASVVVSDINADAANHVV 52 ++ G G+G G A A G V V+D + Sbjct: 36 LVIGGGSG-GLACAKEAAQLGKKVAVADYVEPSPRGTK 72 >5GXF-A nrPDB Length = 330 Score = 29.8 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 9/36 (25%), Positives = 14/36 (38%) Query: 14 AIITGAGAGIGKEIAITFATAGASVVVSDINADAAN 49 ++TGA G+G A G V + A+ Sbjct: 153 VLVTGAAGGVGSVATAILAHLGYEVAAVTGRPETAD 188 >3H9U-A nrPDB Length = 436 Score = 29.8 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 20/102 (19%), Positives = 39/102 (38%), Gaps = 15/102 (14%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDE------IQQLGGQAF 63 GK A + G G +GK A GA VVV++++ A E ++ + +A Sbjct: 210 AGKTACVCGYGD-VGKGCAAALRGFGARVVVTEVDPINALQAAMEGYQVLLVEDVVEEAH 268 Query: 64 ACRCDITSEQELSALADFAISKLGKV--DILVNNAGGGGPKP 103 ++ +++ ++ D +V N G + Sbjct: 269 IFVTTTGNDDIITS------EHFPRMRDDAIVCNIGHFDTEI 304 >6BII-A nrPDB Length = 333 Score = 29.8 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 38/92 (41%), Gaps = 7/92 (7%) Query: 11 GKCAIITGAGAGIGKEIAITFATAGASVVVSDINA--DAANHVVDE---IQQLGGQAFAC 65 GK I G G IG+ IA G ++ + + +A + E +++L ++ Sbjct: 150 GKTIGIVGFGR-IGQAIAKRAKGFGMRILYTARSRKPEAEKELGAEFKPLEELLRESDFV 208 Query: 66 RCDITSEQELSALADFAISKLGKVD-ILVNNA 96 + +E + + +L K +LVN A Sbjct: 209 VLAVPLTKETYHMINEERLRLMKPTAVLVNVA 240 >1YXY-A nrPDB Length = 234 Score = 29.8 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 21/57 (36%), Gaps = 7/57 (12%) Query: 131 PEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGI 187 ME+ GG+I++ Y+ + L+ A + G IR N + Sbjct: 9 KLMEQLKGGIIVSC------QALPGEPLYSET-GGIMPLMAKAAQEAGAVGIRANSV 58 >4QPN-A nrPDB Length = 227 Score = 29.8 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 15/42 (35%), Positives = 19/42 (45%), Gaps = 3/42 (7%) Query: 2 FNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDI 43 F S N+ GK I GAG GI I G V ++D+ Sbjct: 68 FESQNVDFRGKKVIELGAGTGI-VGILAAL--QGGDVTITDL 106 >1YB5-A nrPDB Length = 351 Score = 29.8 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 22/133 (16%), Positives = 42/133 (31%), Gaps = 28/133 (21%) Query: 10 DGKCAIITGAGAGIGKE---IAITF-----------------ATAGASVVVSDINADAAN 49 G+ ++ GA G+G IA + GA V + + + Sbjct: 170 AGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFNHREVNYID 229 Query: 50 HVVDEIQQLGGQAFA-CRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPM 108 + + + G ++ ++LS L G I+V + G P D Sbjct: 230 KIKKYVGEKGIDIIIEMLANVNLSKDLSLL------SHGGRVIVVGSRGTIEINPRDTMA 283 Query: 109 ADFRRAYELNVFS 121 + + +FS Sbjct: 284 KE-SSIIGVTLFS 295 >3R9I-A nrPDB Length = 260 Score = 29.8 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 26/86 (30%), Gaps = 7/86 (8%) Query: 12 KCAIITGAGAGIGK-----EIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 + ++T G+GK IA A G VV D +D I + Sbjct: 3 RIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVIDF--AIGLRNLDLIMGCERRVVYDF 60 Query: 67 CDITSEQELSALADFAISKLGKVDIL 92 ++ A + + IL Sbjct: 61 VNVIQGDATLNQALIKDKRTENLYIL 86 >4UUP-A nrPDB Length = 341 Score = 29.8 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 32/103 (31%), Gaps = 16/103 (15%) Query: 14 AIITGAGAGIGKEIAITFATA---GASVVVSDINA-----DAANHVVDEIQQLGGQAFAC 65 +ITGA IG +A A G VV + A V E+Q A Sbjct: 7 VLITGAAGQIGYALAFRIAKGDLFGDRKVVLHLLEIPPAMKALEGVCMELQDCAFPTLAG 66 Query: 66 RCDITSEQELSALADFA--------ISKLGKVDILVNNAGGGG 100 +E D A + + D+L NAG Sbjct: 67 VVATDDPEEAFKDVDVAFLVGSFPRKPGMERADLLEKNAGIFK 109 >4WOK-A nrPDB Length = 336 Score = 29.8 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 29/182 (15%), Positives = 50/182 (27%), Gaps = 32/182 (17%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSE 72 ++ G IG A A G + VV D + V DI + Sbjct: 13 NVLVVGGAGFIGSHTAKLLAGQGYAPVVYDNLSTGHQSAVRW-------GDFVEGDILDQ 65 Query: 73 QELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLVAPE 132 L + V + D + Y NV +Q + Sbjct: 66 ARLVETMEKYAP--------VAVIHFAASAYVGESVEDPAKYYRNNVGG----TQSLLDA 113 Query: 133 MEKNGGGVILTITSMA------------AENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 ++ +S A E +N + Y +K A H++ + A G + Sbjct: 114 CRLTRTQNVIFSSSCATYGVPSRLPIGEGEAQNP-INPYGRTKLIAEHMLADYAVAYGLR 172 Query: 181 NI 182 + Sbjct: 173 YV 174 >3DQQ-A nrPDB Length = 421 Score = 29.4 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 14/50 (28%) Query: 141 ILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPG 190 I S A + A L +A L E I +A G Sbjct: 313 ISATASTQALAAIQQQYGATEASHAVEALFSLLAARLAEGGITRFIVAGG 362 >2WEK-A nrPDB Length = 341 Score = 29.4 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 9/39 (23%), Positives = 19/39 (48%), Gaps = 2/39 (5%) Query: 10 DGKCAIITGAGAGIGKEIAITFA-TAGASVVVSDINADA 47 +GK ++T A G G+ A+ + A V+ + + + Sbjct: 142 EGKKVLVTAAAGGTGQ-FAMQLSKKAKCHVIGTCSSDEK 179 >1TLL-A nrPDB Length = 688 Score = 29.4 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 9/47 (19%), Positives = 21/47 (44%), Gaps = 1/47 (2%) Query: 43 INADAANHVVDEIQQLGGQAFACRCDITSEQELSALADFAISKLGKV 89 + A V +++ GG + C D+T ++ +++ GK+ Sbjct: 586 LQEQLAESVYRALKEQGGHIYVC-GDVTMAADVLKAIQRIMTQQGKL 631 >2OWO-A nrPDB Length = 671 Score = 29.4 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 13/72 (18%), Positives = 25/72 (34%), Gaps = 1/72 (1%) Query: 9 LDGKCAIITGAGAGIGKEIAI-TFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 GK ++TG+ + + ++ A GA V S + +A Sbjct: 598 FAGKTVVLTGSLSQMSRDDAKARLVELGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGI 657 Query: 68 DITSEQELSALA 79 ++ E E+ L Sbjct: 658 EVIDEAEMLRLL 669 >4WLE-A nrPDB Length = 340 Score = 29.4 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 21/130 (16%), Positives = 41/130 (31%), Gaps = 25/130 (19%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITS 71 K A + GA GIG+ +++ + + + +I G D++ Sbjct: 28 KVA-VLGASGGIGQPLSLLLKN----------SPLVSRLTLYDIAHTPG----VAADLSH 72 Query: 72 EQELSALA-----DFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLS 126 + +A+ + L D++V AG M D + N L+ Sbjct: 73 IETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPG--MTRDD---LFNTNATIVATLT 127 Query: 127 QLVAPEMEKN 136 A + Sbjct: 128 AACAQHCPEA 137 >5EGS-A nrPDB Length = 376 Score = 29.4 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 30/78 (38%), Gaps = 8/78 (10%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 L GK + GAG GI ++I A AGA V + + + ++ G + Sbjct: 82 LRGKTVLDVGAGTGI---LSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLP 138 Query: 69 -----ITSEQELSALADF 81 + +++ A+ Sbjct: 139 GPVETVELPEQVDAIVSE 156 >2DFV-A nrPDB Length = 347 Score = 29.4 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 22/78 (28%), Positives = 31/78 (39%), Gaps = 7/78 (8%) Query: 10 DGKCAIITGAGAGIG-KEIAITFATAGASVVV---SDINADAANHVVDE--IQQLGGQAF 63 GK +ITGAG +G IA+ A+ V+V SD + A V + I Sbjct: 166 SGKSVLITGAGP-LGLLGIAVAKASGAYPVIVSEPSDFRRELAKKVGADYVINPFEEDVV 224 Query: 64 ACRCDITSEQELSALADF 81 DIT + +F Sbjct: 225 KEVMDITDGNGVDVFLEF 242 >1ZCJ-A nrPDB Length = 463 Score = 29.4 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 17/33 (51%) Query: 23 IGKEIAITFATAGASVVVSDINADAANHVVDEI 55 +G+ IAI+FA G SVV + + + I Sbjct: 48 MGRGIAISFARVGISVVAVESDPKQLDAAKKII 80 >6H0D-A nrPDB Length = 403 Score = 29.0 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 25/60 (41%), Gaps = 8/60 (13%) Query: 13 CAIITGAGAG----IGKEIAITFATAGASVVVSDINADA--ANHVVDEIQQLGGQAFACR 66 A+I + G + + IA AG V V+ INA+ A + + I + G F Sbjct: 258 VALIYASAYGNTSTLAQAIARGITKAG--VAVTAINAETSNAEEIKEAIGKSAGFIFGSP 315 >3H0K-A nrPDB Length = 178 Score = 29.0 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 18/100 (18%), Positives = 33/100 (33%), Gaps = 25/100 (25%) Query: 12 KCAIITGAGAGIGK-EIAITFATAGASVVVS-----------DINADAANHVVDEIQQLG 59 K +ITG G GK E A GA V+V + ++++ Sbjct: 1 KVILITG-MPGSGKSEFAKLLKERGAKVIVMSDVVRKRYSIEAKPGERLMDFAKRLREIY 59 Query: 60 GQAFACRC----------DITSEQELSALADFAISKLGKV 89 G R D+ + +LA+ + + ++ Sbjct: 60 GDGVVARLCVEELGTSNHDLVVFDGVRSLAE--VEEFKRL 97 >2ZJ1-A nrPDB Length = 495 Score = 29.0 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 27/111 (24%), Positives = 42/111 (37%), Gaps = 13/111 (11%) Query: 11 GKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANH-------VVDEIQQLGGQAF 63 GK +I G G +GK A GA V V++I+ A VV + +G Sbjct: 275 GKKVLICGYGD-VGKGCAEAMKGQGARVSVTEIDPINALQAMMEGFDVVTVEEAIGDADI 333 Query: 64 ACRC----DITSEQELSALADFAI-SKLGKVDILVNNAGGGGPKPFDMPMA 109 DI + + A+ D AI +G D ++ AG + + Sbjct: 334 VVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAGLERSGATRVNVK 384 >3OPY-A nrPDB Length = 989 Score = 29.0 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 22/123 (17%), Positives = 33/123 (26%), Gaps = 18/123 (14%) Query: 10 DGKCAIIT--GAGAGIGKEIAITFATAG----ASVVVSDINADAANHVVDEIQQLGGQAF 63 K AIIT G G+ AG V D +++L Q Sbjct: 210 KKKIAIITSGGDAPGM-NAAVRAVTRAGIFYGCKVYACYEGYTGLVKGGDMLKELQWQDV 268 Query: 64 ACRCDITSEQELSALADFAISKLGK-----------VDILVNNAGGGGPKPFDMPMADFR 112 I +A + G+ +D LV G G D+ ++ Sbjct: 269 RGLLSIGGTIIGTARCKEFRERWGRLQACYNMVSNGIDALVVCGGDGSLTGADLFRKEWP 328 Query: 113 RAY 115 Sbjct: 329 ELI 331 >3ZWA-A nrPDB Length = 742 Score = 29.0 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 17/33 (51%) Query: 23 IGKEIAITFATAGASVVVSDINADAANHVVDEI 55 +G+ IAI+FA G SVV + + + I Sbjct: 327 MGRGIAISFARVGISVVAVESDPKQLDAAKKII 359 >1MLD-A nrPDB Length = 314 Score = 29.0 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 20/130 (15%), Positives = 39/130 (30%), Gaps = 25/130 (19%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITS 71 K A + GA GIG+ +++ + + + +I G D++ Sbjct: 2 KVA-VLGASGGIGQPLSLLLKN----------SPLVSRLTLYDIAHTPG----VAADLSH 46 Query: 72 EQELSALA-----DFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLS 126 + + + + L D++V AG M D + N L+ Sbjct: 47 IETRATVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPG--MTRDD---LFNTNATIVATLT 101 Query: 127 QLVAPEMEKN 136 A Sbjct: 102 AACAQHCPDA 111 >1EDZ-A nrPDB Length = 320 Score = 29.0 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 13/37 (35%), Positives = 19/37 (51%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN 44 RL GK I+ +G+ +A A GA+V D+N Sbjct: 174 RLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVN 210 >3IP1-A nrPDB Length = 404 Score = 29.0 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 27/72 (37%), Gaps = 7/72 (9%) Query: 11 GKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDIT 70 G +I G G IG AGAS V+ ++ ++ E+ D T Sbjct: 214 GDNVVILGGGP-IGLAAVAILKHAGASKVILSEPSEVRRNLAKELGAD------HVIDPT 266 Query: 71 SEQELSALADFA 82 E + A+ D+ Sbjct: 267 KENFVEAVLDYT 278 >5IOB-A nrPDB Length = 348 Score = 29.0 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 7/48 (14%), Positives = 17/48 (35%) Query: 138 GGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVN 185 GG + T++ + + + + + L + L + VN Sbjct: 94 GGRVQRATNILGDFPSPRVMAQTMTPEQVEDLAEILGTGLAAHGVTVN 141 >3JYO-A nrPDB Length = 283 Score = 29.0 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 25/60 (41%), Gaps = 1/60 (1%) Query: 26 EIAITFATAGA-SVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQELSALADFAIS 84 +A T G + V+D++ A + D I G+ D +++ A AD ++ Sbjct: 141 AVAYALVTHGVQKLQVADLDTSRAQALADVINNAVGREAVVGVDARGIEDVIAAADGVVN 200 >2XHZ-A nrPDB Length = 183 Score = 29.0 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 11/27 (40%), Positives = 17/27 (62%), Gaps = 1/27 (3%) Query: 10 DGKCAII-TGAGAGIGKEIAITFATAG 35 GK ++ GA IG+++A TFA+ G Sbjct: 49 KGKVVVMGMGASGHIGRKMAATFASTG 75 >3ZXS-A nrPDB Length = 522 Score = 29.0 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 21/74 (28%), Gaps = 11/74 (14%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVS-----DINADAANHVVDEIQQLGGQ--AFA 64 K A+I A + A G V S D ++ + G + Sbjct: 61 KIALILAAMR----KFARRLQERGFRVAYSRLDDPDTGPSIGAELLRRAAETGAREAVAT 116 Query: 65 CRCDITSEQELSAL 78 D + L A+ Sbjct: 117 RPGDWRLIEALEAM 130 >6APE-A nrPDB Length = 298 Score = 29.0 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 15/38 (39%), Positives = 21/38 (55%) Query: 6 NLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDI 43 ++ + GK I GA IGK +++ AGASV V I Sbjct: 165 HIEIKGKDVAIIGASNIIGKPLSMLMLNAGASVSVCHI 202 >4XRR-A nrPDB Length = 456 Score = 28.6 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 14/93 (15%), Positives = 28/93 (30%), Gaps = 3/93 (3%) Query: 15 IITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQE 74 ++ +G +A+T A GA VV D + + + + Sbjct: 18 VVIAGAGYVGTCLAVTLAGRGAEVVAVDSDPGTVADL--RAGRCRLPEPGLAGAVRDLAA 75 Query: 75 LSALADFA-ISKLGKVDILVNNAGGGGPKPFDM 106 L +G D+++ G +M Sbjct: 76 TGRLTASTSYDPVGAADVVIVTVGTPTDAGHEM 108 >4FQ8-A nrPDB Length = 271 Score = 28.6 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 13/46 (28%), Positives = 19/46 (41%), Gaps = 4/46 (8%) Query: 7 LRLDGKC---AIITGAGAGIGKEIAITFATAGASVVVSDINADAAN 49 L L K A+I GAG K +A G V V + ++ + Sbjct: 111 LSLKQKNYQNALILGAGGS-AKALACELKKQGLQVSVLNRSSRGLD 155 >3DC2-A nrPDB Length = 529 Score = 28.6 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 24/92 (26%), Positives = 33/92 (35%), Gaps = 6/92 (6%) Query: 11 GKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD-- 68 GK + G G IG+ +A A GA VV D A I+ L R D Sbjct: 142 GKTVGVVGLGR-IGQLVAQRIAAFGAYVVAYDPYVSPARAAQLGIELLSLDDLLARADFI 200 Query: 69 ---ITSEQELSALADFAISKLGKVDILVNNAG 97 + E + L D K +++ NA Sbjct: 201 SVHLPKTPETAGLIDKEALAKTKPGVIIVNAA 232 >5H02-A nrPDB Length = 283 Score = 28.6 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 9/41 (21%), Positives = 16/41 (39%) Query: 28 AITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 ++ AG VV +D +A+ D + G + D Sbjct: 94 SVRLLQAGFDVVSADGSAEMLVKAFDNARDHGYLMRTVQAD 134 >3FBG-A nrPDB Length = 346 Score = 28.6 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 17/41 (41%), Gaps = 2/41 (4%) Query: 10 DGKCAIITGAGAGIGKEIAITFATA-GASVVVSDINADAAN 49 +GK +I G+G IA A A G V+ + + Sbjct: 150 EGKTLLIINGAGGVG-SIATQIAKAYGLRVITTASRNETIE 189 >1U3W-A nrPDB Length = 374 Score = 28.6 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 19/98 (19%), Positives = 35/98 (35%), Gaps = 18/98 (18%) Query: 12 KCAIITGAG-------AGIGKEIAITFATAG-ASVVVSDINADAANHVVDEIQQLGGQAF 63 K A +T G+G + + AG A ++ DIN D ++LG Sbjct: 185 KVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKA----KELGATEC 240 Query: 64 ACRCDITSE------QELSALADFAISKLGKVDILVNN 95 D + DF+ +G++D ++ + Sbjct: 241 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGQLDTMMAS 278 >3F6T-A nrPDB Length = 533 Score = 28.6 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 35/93 (37%), Gaps = 13/93 (13%) Query: 121 SFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEK 180 F +S+ + +KN I + A N N A VR + F + E Sbjct: 14 GAFEISRKMLALAQKNEKSNIF----LNAGRGNPNW----IQTLARLAFVRLVQFGVTES 65 Query: 181 NIRVN-GIAPGAILTDA----LKSVITPEIEQK 208 + +N GI G I TD L + + P+ + Sbjct: 66 KLTINNGIMAGYINTDGIRERLFAFLDPDKNDE 98 >2YQ5-A nrPDB Length = 343 Score = 28.6 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 8/21 (38%), Positives = 12/21 (57%) Query: 23 IGKEIAITFATAGASVVVSDI 43 IG +A F+ GA V+ D+ Sbjct: 159 IGSAVAEIFSAMGAKVIAYDV 179 >3E23-A nrPDB Length = 211 Score = 28.6 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 7/45 (15%), Positives = 13/45 (28%) Query: 28 AITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSE 72 A AG V +D + + A + + + D Sbjct: 58 AEAMLAAGFDVDATDGSPELAAEASRRLGRPVRTMLFHQLDAIDA 102 >3K6J-A nrPDB Length = 460 Score = 28.6 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 12/41 (29%), Positives = 17/41 (41%), Gaps = 2/41 (4%) Query: 13 CAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVD 53 AII G +GK +AI F AG + N ++ Sbjct: 57 VAIIGGGT--MGKAMAICFGLAGIETFLVVRNEQRCKQELE 95 >1SQG-A nrPDB Length = 429 Score = 28.6 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 18/33 (54%) Query: 36 ASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 A VV DI+ + V D +++LG +A + D Sbjct: 271 AQVVAVDIDEQRLSRVYDNLKRLGMKATVKQGD 303 >2VCY-A nrPDB Length = 344 Score = 28.2 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 13/86 (15%), Positives = 29/86 (33%), Gaps = 5/86 (5%) Query: 19 AGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQELSAL 78 + +G+G+ + A G + + + D ++ LG + IT E+ Sbjct: 163 SNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHV-----ITEEELRRPE 217 Query: 79 ADFAISKLGKVDILVNNAGGGGPKPF 104 + + + +N GG Sbjct: 218 MKNFFKDMPQPRLALNCVGGKSSTEL 243 >5XF9-B nrPDB Length = 242 Score = 28.2 bits (62), Expect = 3.4, Method: Composition-based stats. Identities = 11/44 (25%), Positives = 17/44 (38%), Gaps = 12/44 (27%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGAS-------VVVSDINAD 46 +GK A++ G G+ IA AS + +D A Sbjct: 166 EGKEALVIG-----GRGIASRLLATSASGRLGDTALAATDRAAR 204 >5G1T-A nrPDB Length = 256 Score = 28.2 bits (62), Expect = 3.4, Method: Composition-based stats. Identities = 10/47 (21%), Positives = 18/47 (38%), Gaps = 1/47 (2%) Query: 28 AITFATAG-ASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQ 73 AG A VV+ + + V ++ G QA D+ ++ Sbjct: 91 VAALLKAGVARVVIGSTAVKSPDVVKGWFERFGAQALVLALDVRIDE 137 >3HG7-A nrPDB Length = 324 Score = 28.2 bits (62), Expect = 3.4, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 20/61 (32%), Gaps = 1/61 (1%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD 68 L G+ +I G IG+ IA T G V+ + Q + D Sbjct: 138 LKGRTLLILG-TGSIGQHIAHTGKHFGMKVLGVSRSGRERAGFDQVYQLPALNKMLAQAD 196 Query: 69 I 69 + Sbjct: 197 V 197 >4GBJ-A nrPDB Length = 297 Score = 28.2 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 27/78 (34%), Gaps = 16/78 (20%) Query: 23 IGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCD-----------ITS 71 +G IA AG +VV + A A + + +LG D + Sbjct: 16 LGTPIAEILLEAGYELVVWNRTASKA----EPLTKLGATVVENAIDAITPGGIVFSVLAD 71 Query: 72 EQELSALAD-FAISKLGK 88 + + L + KLGK Sbjct: 72 DAAVEELFSMELVEKLGK 89 >2V6G-A nrPDB Length = 364 Score = 28.2 bits (62), Expect = 3.6, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 21/70 (30%), Gaps = 12/70 (17%) Query: 13 CAIITGAGAGIGKEIAITFATAG-----ASVVVSDINADAANHVVDEIQQLGGQAFACRC 67 A+I G IG +A A V A H + I +C Sbjct: 3 VALIVGVTGIIGNSLAEILPLADTPGGPWKVYGVARRTRPAWHEDNPIN-------YVQC 55 Query: 68 DITSEQELSA 77 DI+ + A Sbjct: 56 DISDPDDSQA 65 >2P0Y-A nrPDB Length = 341 Score = 28.2 bits (62), Expect = 3.7, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 27/77 (35%), Gaps = 8/77 (10%) Query: 140 VILTITSMAAENKNINMTSYASSKAAA-SHLVRNMAFDLGEKNI---RVNGIAPGAILTD 195 I+ I +N K A V +A D G I VN + PG I Sbjct: 12 KIVVIGGGTGLPVVLN----GLRKQAVDITAVVTVADDGGSSGIIRNYVNVVPPGDIRNV 67 Query: 196 ALKSVITPEIEQKMLQH 212 + P++ + + Q+ Sbjct: 68 MVALSSWPDLYKDIFQY 84 >4IYO-A nrPDB Length = 397 Score = 27.9 bits (61), Expect = 4.1, Method: Composition-based stats. Identities = 11/86 (12%), Positives = 21/86 (24%), Gaps = 7/86 (8%) Query: 3 NSDNLRLDGKCAIITGAGAGIGKE-------IAITFATAGASVVVSDINADAANHVVDEI 55 N + A + G + AG+ VV D + + + Sbjct: 63 NPTRFAYERCVAALEGGTRAFAFASGMAATSTVMELLDAGSHVVAMDDLYGGTFRLFERV 122 Query: 56 QQLGGQAFACRCDITSEQELSALADF 81 ++ D+T A Sbjct: 123 RRRTAGLDFSFVDLTDPAAFKAAIRA 148 >1NHQ-A nrPDB Length = 447 Score = 27.9 bits (61), Expect = 4.1, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 18/44 (40%), Gaps = 6/44 (13%) Query: 6 NLRLDGKCA------IITGAGAGIGKEIAITFATAGASVVVSDI 43 ++L K ++ IG E A FA AG V V DI Sbjct: 137 AIKLKQKTVDPEVNNVVVIGSGYIGIEAAEAFAKAGKKVTVIDI 180 >2BC1-A nrPDB Length = 490 Score = 27.9 bits (61), Expect = 4.1, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 16/33 (48%), Gaps = 2/33 (6%) Query: 11 GKCAIITGAGAGIGKEIAITFATAGASVVVSDI 43 + A++ IG E+A F G VV+ D+ Sbjct: 195 KRVAVV--GAGYIGVELAEAFQRKGKEVVLIDV 225 >3RUE-A nrPDB Length = 351 Score = 27.9 bits (61), Expect = 4.2, Method: Composition-based stats. Identities = 20/125 (16%), Positives = 37/125 (29%), Gaps = 19/125 (15%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLG-----GQAFACR 66 K +ITG IG + V+ D + + +DE++ L + Sbjct: 26 KTWLITGVAGFIGSNLLEKLLKLNQVVIGLDNFSTGHQYNLDEVKTLVSTEQWSRFCFIE 85 Query: 67 CDITSEQELSALADFAISKLGKVDILVNNA--GGGGPKPFDMPMADFRRAYELNVFSFFH 124 DI + VD +++ A G D + N+ F + Sbjct: 86 GDIRDLTTCEQVMK-------GVDHVLHQAALGSVPRSIVDPITTN-----ATNITGFLN 133 Query: 125 LSQLV 129 + Sbjct: 134 ILHAA 138 >2IY3-A nrPDB Length = 432 Score = 27.9 bits (61), Expect = 4.2, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 27/79 (34%), Gaps = 1/79 (1%) Query: 38 VVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAG 97 +V +D AA + + + G D S + + + + ILV+ AG Sbjct: 131 LVAADTQRPAAREQLRLLGEKVGVPVLEVMDGESPESIRRRVEEKARLEARDLILVDTAG 190 Query: 98 -GGGPKPFDMPMADFRRAY 115 +P +A + Sbjct: 191 RLQIDEPLMGELARLKEVL 209 >4BM5-A nrPDB Length = 348 Score = 27.9 bits (61), Expect = 4.4, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 27/69 (39%), Gaps = 2/69 (2%) Query: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQ 127 D+ + + F + G + I ++N + + M + + Y +N+ F L Sbjct: 7 DVGDDPFVRRAGAFLGIEAGTITIELSNLIDFYIRNGILEMENEQAVYPVNLRGVFDL-- 64 Query: 128 LVAPEMEKN 136 + EM + Sbjct: 65 NILQEMYRQ 73 >6H5E-B nrPDB Length = 437 Score = 27.9 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 25/67 (37%), Gaps = 1/67 (1%) Query: 32 ATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDIT-SEQELSALADFAISKLGKVD 90 A A + + I + I+ G ++T S + + + G++D Sbjct: 84 ANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEID 143 Query: 91 ILVNNAG 97 I+VNN Sbjct: 144 IMVNNIA 150 >6F4U-A nrPDB Length = 341 Score = 27.9 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 23/52 (44%) Query: 113 RAYELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKA 164 + + N + QL+ ++K G I+ + S ++ + + +Y KA Sbjct: 120 KLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKA 171 >6F02-A nrPDB Length = 389 Score = 27.9 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 23/52 (44%) Query: 113 RAYELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKA 164 + + N + QL+ ++K G I+ + S ++ + + +Y KA Sbjct: 122 KLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKA 173 >3UOG-A nrPDB Length = 363 Score = 27.9 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 20/52 (38%), Gaps = 5/52 (9%) Query: 10 DGKCAII--TGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLG 59 G ++ TG A G +IA GA V+V+ + + + G Sbjct: 189 AGDRVVVQGTGGVALFGLQIAKA---TGAEVIVTSSSREKLDRAFALGADHG 237 >3D64-A nrPDB Length = 494 Score = 27.9 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 15/45 (33%), Positives = 23/45 (51%), Gaps = 1/45 (2%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDE 54 GK A++ G G +GK A + GA+V V++I+ A E Sbjct: 276 AGKIAVVAGYGD-VGKGCAQSLRGLGATVWVTEIDPICALQAAME 319 >4N5F-A nrPDB Length = 385 Score = 27.9 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 13/91 (14%), Positives = 29/91 (31%), Gaps = 1/91 (1%) Query: 19 AGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQELSAL 78 G G +IA++ G + ++ A D+ ++ G+ I Q + Sbjct: 234 GNRGEGLKIALS-NLEGGRIGIAAQALGIARAAFDKARRYAGERVQFGKPIAEHQAIQQK 292 Query: 79 ADFAISKLGKVDILVNNAGGGGPKPFDMPMA 109 ++ +LV++A Sbjct: 293 LADMAVQINAARLLVHHAAKLRTAGLPCLSE 323 >4MM1-A nrPDB Length = 250 Score = 27.9 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 15/44 (34%), Positives = 26/44 (59%), Gaps = 1/44 (2%) Query: 14 AIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQ 57 +I G G G++ A A AGA VVV+ + +++V D+I++ Sbjct: 198 ILIVGGGIRSGEDAARV-AGAGADVVVTGTVVENSDNVEDKIRE 240 >3GFB-A nrPDB Length = 350 Score = 27.9 bits (61), Expect = 4.8, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 28/80 (35%), Gaps = 11/80 (13%) Query: 10 DGKCAIITGAG--AGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQ------LGGQ 61 G+ +ITGAG +G +A +GA V+ ++ + ++ Sbjct: 167 AGRSTLITGAGPLGLLGIAVAKA---SGAYPVIVSEPSEFRRKLAKKVGADYVVNPFEED 223 Query: 62 AFACRCDITSEQELSALADF 81 DIT + +F Sbjct: 224 PVKFVMDITDGAGVEVFLEF 243 >4OMU-A nrPDB Length = 283 Score = 27.9 bits (61), Expect = 4.9, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 25/52 (48%), Gaps = 2/52 (3%) Query: 9 LDGKCAIITGAGAGIGKEIAI-TFATAGASVVVSDINADAANHVVDEIQQLG 59 L GK +I GAG + + + A S+V+++ + A + E +LG Sbjct: 117 LAGKRILILGAGGAV-RGVLEPILAHKPQSLVIANRTVEKAEQLAREFDELG 167 >4R16-A nrPDB Length = 418 Score = 27.9 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 16/29 (55%) Query: 23 IGKEIAITFATAGASVVVSDINADAANHV 51 IG AI FA++G VV DI ++ + Sbjct: 11 IGLPTAIMFASSGYDVVGYDIRSEVIKKI 39 >2D0I-A nrPDB Length = 333 Score = 27.9 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 19/50 (38%), Gaps = 3/50 (6%) Query: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQ 57 L GK I G IGK IA G V + + +V E++ Sbjct: 143 SLYGKKVGILG-MGAIGKAIARRLIPFG--VKLYYWSRHRKVNVEKELKA 189 >3VR3-A nrPDB Length = 600 Score = 27.9 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 25/66 (37%), Gaps = 3/66 (4%) Query: 24 GKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQELSALADFAI 83 G IA F G V + AD+ + + ++++ G+ D L + Sbjct: 317 GITIAEYFRDMGYDVAIM---ADSTSRWAEALREMSGRLEEMPGDEGYPAYLGSRLAEYY 373 Query: 84 SKLGKV 89 + G+V Sbjct: 374 ERSGRV 379 >4V6H-A nrPDB Length = 484 Score = 27.9 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 33/80 (41%), Gaps = 8/80 (10%) Query: 10 DGKCAIITGAGAGIGKEI-----AITFATAGASVVVSDINADAANHVVDEIQQLGGQAFA 64 G +++ G IG EI + G++ V + A +A V +LGG A Sbjct: 205 KGVLSVVIGDPKAIGTEITSNPIVRKLSFTGSTAVGRLLMAQSAPTVKKLTLELGGNAPF 264 Query: 65 CRCDITSEQELSALADFAIS 84 D + +L A + AI+ Sbjct: 265 IVFD---DADLDAAVEGAIA 281 >3S8M-A nrPDB Length = 422 Score = 27.9 bits (61), Expect = 5.1, Method: Composition-based stats. Identities = 17/96 (17%), Positives = 33/96 (34%), Gaps = 14/96 (14%) Query: 12 KCAIITGAGAGIGKE----IAITFATAGASVVV----SDINADAA-----NHVVDEIQQL 58 K ++ GA +G G A F V + A A + Sbjct: 62 KKVLVIGASSGYGLASRITAAFGFGADTLGVFFEKPGTASKAGTAGWYNSAAFDKHAKAA 121 Query: 59 GGQAFACRCDITSEQELSALADFAISKLGK-VDILV 93 G + + D S+ + + + +++G VD++V Sbjct: 122 GLYSKSINGDAFSDAARAQVIELIKTEMGGQVDLVV 157 >2FFH-A nrPDB Length = 425 Score = 27.5 bits (60), Expect = 5.4, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 27/79 (34%), Gaps = 1/79 (1%) Query: 38 VVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAG 97 +V +D AA + + + G D S + + + + ILV+ AG Sbjct: 131 LVAADTQRPAAREQLRLLGEKVGVPVLEVMDGESPESIRRRVEEKARLEARDLILVDTAG 190 Query: 98 -GGGPKPFDMPMADFRRAY 115 +P +A + Sbjct: 191 RLQIDEPLMGELARLKEVL 209 >2RIR-A nrPDB Length = 300 Score = 27.5 bits (60), Expect = 5.6, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 18/35 (51%), Gaps = 3/35 (8%) Query: 22 GIGKE---IAITFATAGASVVVSDINADAANHVVD 53 G+G+ IA TFA GA+V V ++ + + Sbjct: 164 GLGRTGMTIARTFAALGANVKVGARSSAHLARITE 198 >2C2Y-A nrPDB Length = 281 Score = 27.5 bits (60), Expect = 6.1, Method: Composition-based stats. Identities = 20/87 (22%), Positives = 27/87 (31%), Gaps = 13/87 (14%) Query: 25 KEIAITFAT-----AGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQELSALA 79 + I AGA VVV + + + A C T ++L AL Sbjct: 143 RGIVHLLRRYDISIAGAHVVVIGRGVTVGRPLGLLLTRRSENATVTLCH-TGTRDLPALT 201 Query: 80 DFAISKLGKVDILVNNAGGGGPKPFDM 106 A DI+V G DM Sbjct: 202 RQA-------DIVVAAVGVAHLLTADM 221 >4OFX-A nrPDB Length = 319 Score = 27.5 bits (60), Expect = 6.2, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 30/78 (38%), Gaps = 5/78 (6%) Query: 17 TGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDIT--SEQE 74 T GIG IA+ A G V+++ + ++ ++ LG + + + Sbjct: 73 TSGNTGIG--IALAGAVKGYRVIIT-MPEKMSHEKQVVLEALGATIYRTPTEAAYDDPES 129 Query: 75 LSALADFAISKLGKVDIL 92 +LA ++ IL Sbjct: 130 HISLAKRLNQEIPNSYIL 147 >3L07-A nrPDB Length = 285 Score = 27.5 bits (60), Expect = 6.2, Method: Composition-based stats. Identities = 22/128 (17%), Positives = 47/128 (36%), Gaps = 8/128 (6%) Query: 10 DGKCAIITGAGAGIGKEIAITFATAGASVVVSDI---NADAANHVVDEIQQLGGQAFACR 66 +G A++ GA +GK ++ A A+V + + D + G+ Sbjct: 160 EGAYAVVVGASNVVGKPVSQLLLNAKATVTTCHRFTTDLKSHTTKADILIVAVGKPNFIT 219 Query: 67 CDITSEQELSALADFAISKL-GKVDILVNNAGGGGPKPFDMPMADFRRAYELN--VFSFF 123 D+ E + + D I+ + GK+ V+ A P+ + +++ F Sbjct: 220 ADMVKEGAV--VIDVGINHVDGKIVGDVDFAAVKDKVAAITPVPGGVGPMTITELLYNTF 277 Query: 124 HLSQLVAP 131 +Q + Sbjct: 278 QCAQELNR 285 >5O2A-B nrPDB Length = 289 Score = 27.5 bits (60), Expect = 6.7, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 23/61 (37%), Gaps = 3/61 (4%) Query: 11 GKCAIITGAGAGIGKEIAITFATAGASVVVSDI---NADAANHVVDEIQQLGGQAFACRC 67 G A++ GA +G+ +++ AG + V+ N D + G+ Sbjct: 160 GLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPG 219 Query: 68 D 68 D Sbjct: 220 D 220 >5DZS-A nrPDB Length = 276 Score = 27.5 bits (60), Expect = 6.7, Method: Composition-based stats. Identities = 9/23 (39%), Positives = 13/23 (56%), Gaps = 2/23 (8%) Query: 1 MFNSDNLRLDGKCAII--TGAGA 21 MF N+ + GK A+I TG + Sbjct: 108 MFKMANIDVQGKVAVILGTGGAS 130 >5MH6-A nrPDB Length = 308 Score = 27.1 bits (59), Expect = 7.1, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 32/96 (33%), Gaps = 7/96 (7%) Query: 7 LRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVV-----DEIQQLGGQ 61 L G+ + G G +G+ + A G VV + D ++V D + + Sbjct: 131 FTLAGERVCVVGLGT-LGRGVVDRAAALGMEVVGVRRSGDPVDNVSTVYTPDRLHEAIAD 189 Query: 62 AFACRCDITSEQELSALADFAISKLGKVDI-LVNNA 96 A E + + + D LVN A Sbjct: 190 ARFVVLATPLTDETEGMVAAPEFETMREDASLVNVA 225 >1RJ9-B nrPDB Length = 300 Score = 27.1 bits (59), Expect = 7.2, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 22/60 (36%) Query: 38 VVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAG 97 +V +D AA + + + G D S + + + + ILV+ AG Sbjct: 131 LVAADTQRPAAREQLRLLGEKVGVPVLEVMDGESPESIRRRVEEKARLEARDLILVDTAG 190 >5GSN-A nrPDB Length = 453 Score = 27.1 bits (59), Expect = 7.4, Method: Composition-based stats. Identities = 10/57 (17%), Positives = 20/57 (35%), Gaps = 2/57 (3%) Query: 3 NSDNLRLDGKCAIITGAGAGIGKEIAITFATAGAS-VVVSDINADAANHVVDEIQQL 58 D +GK ++ GA + ++I GA + +A D ++ Sbjct: 189 FRDAREFEGKDVLVMGASSS-AEDIGSQCWKYGAKSITSCYRSAPMGYAWPDNWEEK 244 >5KIA-A nrPDB Length = 351 Score = 27.1 bits (59), Expect = 7.5, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 22/46 (47%), Gaps = 4/46 (8%) Query: 6 NLRLDGKCAIITGAG--AGIGKEIAITFATAGASVVVSDINADAAN 49 + L G+ +ITGAG + IA +VV++DIN + Sbjct: 167 SFNLVGEDVLITGAGPIGVMAVAIAKHVGAR--NVVITDINDYRLD 210 >3TX2-A nrPDB Length = 251 Score = 27.1 bits (59), Expect = 8.3, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 15/30 (50%), Gaps = 1/30 (3%) Query: 14 AIITGAGAGIGKEIAITFATAG-ASVVVSD 42 A++T AG + I A G A +V++ Sbjct: 18 ALVTAAGDRLASAITGALAERGKAMIVLTG 47 >1EO7-A nrPDB Length = 686 Score = 27.1 bits (59), Expect = 8.3, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 24/75 (32%), Gaps = 5/75 (6%) Query: 31 FATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQELSALADFAISKLGKVD 90 A G ++ + ++ V G DITS ++ G + Sbjct: 508 MAKPGVTITIDGRGFGSSKGTV-----YFGTTAVSGADITSWEDTQIKVKIPAVAGGNYN 562 Query: 91 ILVNNAGGGGPKPFD 105 I V NA G +D Sbjct: 563 IKVANAAGTASNVYD 577 >4A26-A nrPDB Length = 300 Score = 27.1 bits (59), Expect = 8.7, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 15/32 (46%) Query: 9 LDGKCAIITGAGAGIGKEIAITFATAGASVVV 40 + GK A++ G +G +A A+V + Sbjct: 163 MAGKRAVVLGRSNIVGAPVAALLMKENATVTI 194 >3MFY-A nrPDB Length = 588 Score = 27.1 bits (59), Expect = 8.8, Method: Composition-based stats. Identities = 17/106 (16%), Positives = 33/106 (31%), Gaps = 19/106 (17%) Query: 24 GKEIAITFATAGASVVV----SDINADAANHVVDEIQQLGGQAFACRCDITSEQELSALA 79 G IA F G V + + A+A + ++++ G+ + S+ Sbjct: 312 GITIAEYFRDMGYDVALMADSTSRWAEALREISGRLEEMPGE-EGYPAYLASK------L 364 Query: 80 DFAISKLGKVDIL--------VNNAGGGGPKPFDMPMADFRRAYEL 117 + G+V L V+ G P D + + Sbjct: 365 AEFYERAGRVVTLGSDYRVGSVSVIGAVSPPGGDFSEPVVQNTLRV 410 >5F8E-A nrPDB Length = 377 Score = 27.1 bits (59), Expect = 8.8, Method: Composition-based stats. Identities = 21/157 (13%), Positives = 49/157 (31%), Gaps = 19/157 (12%) Query: 33 TAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQELSALADFAISKLGKVDIL 92 +GA V + A V + Q G + D + E + + A L Sbjct: 186 RSGADVADFGCGSGRA---VKLMAQAFGASRFTGIDFSDEAVAAGTEEAARLGL------ 236 Query: 93 VNNAGGGGPKPFDMPMADFRRAYELNVFS------FFHLSQLVAPEMEKNGGGVILTI-- 144 NA ++ + + + Q + + G +++ I Sbjct: 237 -ANATFERHDLAELDKVGAYDVITV-FDAIHDQAQPARVLQNIYRALRPGGVLLMVDIKA 294 Query: 145 TSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKN 181 +S +N + +++Y + + + ++A D Sbjct: 295 SSQLEDNVGVPLSTYLYTTSLMHCMTVSLALDGAGLG 331 >4BKO-A nrPDB Length = 417 Score = 26.7 bits (58), Expect = 9.1, Method: Composition-based stats. Identities = 21/102 (20%), Positives = 32/102 (31%), Gaps = 13/102 (12%) Query: 12 KCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVV-------------DEIQQL 58 K ++ GA G G I A + + A DE Sbjct: 62 KKVLVIGASTGYGLAARIAAAFGAGAATLGVFFERAPADAKPGTAGWYNSAAFHDEAAAR 121 Query: 59 GGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGG 100 G QA + D S++ D LG+VD++V + Sbjct: 122 GLQATSVNGDAFSDEIKHKTIDAIRRDLGQVDLVVYSVAAPR 163 >3PC3-A nrPDB Length = 527 Score = 26.7 bits (58), Expect = 9.5, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 19/47 (40%), Gaps = 3/47 (6%) Query: 17 TGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAF 63 T GIG +A A G ++ + +N V ++ LG + Sbjct: 120 TSGNTGIGLAMA--CAVKGYKCIIV-MPEKMSNEKVSALRTLGAKII 163 >2EFY-A nrPDB Length = 304 Score = 26.7 bits (58), Expect = 9.6, Method: Composition-based stats. Identities = 15/103 (14%), Positives = 27/103 (26%), Gaps = 26/103 (25%) Query: 17 TGAGAGIGKE-IA--------------------ITFATAGASVVVSDINADAANHVVDEI 55 T GIG IA GA +V++D + + Sbjct: 69 TSGNTGIGLAMIAASRGYRLILTMPAQMSEERKRVLKAFGAELVLTDPERRMLAAREEAL 128 Query: 56 QQLGGQAFACRCDITSEQELSALADFAISKL-----GKVDILV 93 + + + A + +L G++D V Sbjct: 129 RLKEELGAFMPDQFKNPANVRAHYETTGPELYEALEGRIDAFV 171 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.160 0.454 Lambda K H 0.267 0.0491 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,146,338 Number of Sequences: 36641 Number of extensions: 476299 Number of successful extensions: 3602 Number of sequences better than 10.0: 463 Number of HSP's better than 10.0 without gapping: 460 Number of HSP's successfully gapped in prelim test: 210 Number of HSP's that attempted gapping in prelim test: 2095 Number of HSP's gapped (non-prelim): 718 length of query: 255 length of database: 10,336,785 effective HSP length: 95 effective length of query: 160 effective length of database: 6,855,890 effective search space: 1096942400 effective search space used: 1096942400 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 59 (27.1 bits)