BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P0AEK4 (262 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4JQC-A nrPDB 537 e-153 5CFZ-A nrPDB 536 e-153 4NR0-A nrPDB 372 e-103 4ZJU-A nrPDB 350 5e-97 5I9N-A nrPDB 335 8e-93 4M89-A nrPDB 322 7e-89 4J3F-A nrPDB 318 1e-87 5KOI-A nrPDB 271 1e-73 5TF4-A nrPDB 263 4e-71 2P91-A nrPDB 263 5e-71 3GRK-A nrPDB 261 2e-70 3OIG-A nrPDB 260 3e-70 5YCX-A nrPDB 242 1e-64 2YW9-A nrPDB 232 1e-61 2PD3-A nrPDB 230 4e-61 3K2E-A nrPDB 230 4e-61 4ALL-A nrPDB 219 1e-57 4NK4-A nrPDB 215 2e-56 4OYR-A nrPDB 115 2e-26 2NTV-A nrPDB 111 2e-25 1ENP-A nrPDB 110 8e-25 2O2S-A nrPDB 102 2e-22 4Q9N-A nrPDB 97 5e-21 3OIC-A nrPDB 86 1e-17 2O2Y-A nrPDB 84 5e-17 3F4B-A nrPDB 84 6e-17 2PTG-A nrPDB 79 2e-15 1AHH-A nrPDB 74 5e-14 1W73-A nrPDB 70 8e-13 3D3W-A nrPDB 70 1e-12 4MOW-A nrPDB 65 2e-11 1O5I-A nrPDB 62 4e-10 2PNF-A nrPDB 61 5e-10 1CYD-A nrPDB 61 6e-10 6CI9-A nrPDB 59 2e-09 1DOH-A nrPDB 59 2e-09 3OSU-A nrPDB 58 4e-09 5T5Q-A nrPDB 56 2e-08 4JRO-A nrPDB 55 2e-08 2UVD-A nrPDB 55 3e-08 3OEC-A nrPDB 55 3e-08 3R3S-A nrPDB 55 3e-08 3WOH-A nrPDB 55 4e-08 3U5T-A nrPDB 54 6e-08 3GRP-A nrPDB 54 6e-08 2ZAT-A nrPDB 54 6e-08 3UF0-A nrPDB 54 7e-08 1AE1-A nrPDB 54 7e-08 4AVY-A nrPDB 53 2e-07 3O4R-A nrPDB 52 2e-07 3UCF-A nrPDB 52 2e-07 1Q7C-A nrPDB 52 2e-07 5CDY-A nrPDB 52 2e-07 2EW8-A nrPDB 52 2e-07 1HXH-A nrPDB 52 2e-07 4FC7-A nrPDB 52 2e-07 4GKB-A nrPDB 52 2e-07 2NM0-A nrPDB 51 5e-07 5OVJ-A nrPDB 50 9e-07 5OVL-A nrPDB 50 1e-06 6NRP-A nrPDB 50 1e-06 4M8S-A nrPDB 49 3e-06 2HQ1-A nrPDB 49 3e-06 3V2G-A nrPDB 47 6e-06 4DMM-A nrPDB 47 8e-06 1K2W-A nrPDB 47 9e-06 4IIN-A nrPDB 47 1e-05 4HP8-A nrPDB 46 2e-05 5YSS-A nrPDB 46 2e-05 3FTP-A nrPDB 46 2e-05 3EMK-A nrPDB 46 2e-05 2QHX-A nrPDB 45 3e-05 2BFA-A nrPDB 45 3e-05 1P33-A nrPDB 45 3e-05 5JS6-A nrPDB 45 4e-05 3RSH-A nrPDB 45 4e-05 4NBV-A nrPDB 45 5e-05 2AE2-A nrPDB 44 5e-05 5OJG-A nrPDB 44 5e-05 3UN1-A nrPDB 44 7e-05 2BGM-A nrPDB 44 9e-05 2AG5-A nrPDB 43 1e-04 1YXM-A nrPDB 43 1e-04 5U9P-A nrPDB 42 3e-04 1GEE-A nrPDB 42 4e-04 3AUT-A nrPDB 42 4e-04 1FJH-A nrPDB 41 4e-04 5ITV-A nrPDB 41 5e-04 3F9I-A nrPDB 41 5e-04 2X9N-A nrPDB 41 6e-04 4BO1-A nrPDB 41 6e-04 1X1T-A nrPDB 41 7e-04 4EGF-A nrPDB 40 9e-04 2FWM-X nrPDB 40 9e-04 4Z9Y-A nrPDB 40 0.001 5B1Y-A nrPDB 40 0.001 1H5Q-A nrPDB 40 0.001 4DA9-A nrPDB 40 0.001 2C07-A nrPDB 40 0.001 2Q2Q-A nrPDB 40 0.001 5JY1-A nrPDB 40 0.001 3EZL-A nrPDB 40 0.001 5EJ2-A nrPDB 39 0.002 2PH3-A nrPDB 39 0.002 4IS3-A nrPDB 39 0.002 4IIV-A nrPDB 39 0.002 3A28-C nrPDB 39 0.002 2B4Q-A nrPDB 39 0.003 3RWB-A nrPDB 38 0.004 3GDF-A nrPDB 38 0.005 4CQL-A nrPDB 37 0.006 4E6P-A nrPDB 37 0.007 3V2H-A nrPDB 37 0.008 3LYL-A nrPDB 37 0.009 3T7C-A nrPDB 36 0.014 1UZM-A nrPDB 36 0.015 4RZH-A nrPDB 36 0.017 3V8B-A nrPDB 36 0.018 4RZI-B nrPDB 36 0.021 4CR6-A nrPDB 35 0.024 3VZS-A nrPDB 35 0.028 1NFF-A nrPDB 34 0.053 6ACF-A nrPDB 34 0.060 2GDZ-A nrPDB 34 0.064 2HSD-A nrPDB 34 0.077 4KMS-A nrPDB 33 0.085 3PPI-A nrPDB 32 0.20 2DKN-A nrPDB 32 0.39 5VT6-A nrPDB 31 0.42 4K6F-A nrPDB 31 0.51 6F4A-B nrPDB 31 0.62 3VPX-A nrPDB 30 0.78 1GEG-A nrPDB 30 1.1 3U4C-A nrPDB 30 1.1 3UVE-A nrPDB 30 1.1 3WYE-A nrPDB 30 1.2 4DBZ-A nrPDB 29 2.2 5O3Z-A nrPDB 29 2.4 2HYP-A nrPDB 29 2.6 3IB8-A nrPDB 29 2.6 3WTC-A nrPDB 28 3.4 3MKQ-B nrPDB 28 4.3 2R8K-A nrPDB 28 5.1 4CEX-C nrPDB 28 5.6 2CFC-A nrPDB 27 6.2 4DRY-A nrPDB 27 7.2 2H92-A nrPDB 27 8.5 >4JQC-A nrPDB Length = 282 Score = 537 bits (1383), Expect = e-153, Method: Compositional matrix adjust. Identities = 262/262 (100%), Positives = 262/262 (100%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 60 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV Sbjct: 21 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 80 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS Sbjct: 81 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 140 Query: 121 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE Sbjct: 141 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 200 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI Sbjct: 201 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 260 Query: 241 SGEVVHVDGGFSIAAMNELELK 262 SGEVVHVDGGFSIAAMNELELK Sbjct: 261 SGEVVHVDGGFSIAAMNELELK 282 >5CFZ-A nrPDB Length = 305 Score = 536 bits (1381), Expect = e-153, Method: Compositional matrix adjust. Identities = 262/262 (100%), Positives = 262/262 (100%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 60 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV Sbjct: 44 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 103 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS Sbjct: 104 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 163 Query: 121 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE Sbjct: 164 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 223 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI Sbjct: 224 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 283 Query: 241 SGEVVHVDGGFSIAAMNELELK 262 SGEVVHVDGGFSIAAMNELELK Sbjct: 284 SGEVVHVDGGFSIAAMNELELK 305 >4NR0-A nrPDB Length = 273 Score = 372 bits (955), Expect = e-103, Method: Compositional matrix adjust. Identities = 182/263 (69%), Positives = 216/263 (82%), Gaps = 3/263 (1%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGS--D 58 MGFL+GKR L+ GVASKLSIA GIA AMHREGAELAFTYQNDKL+GRVEEFA+ GS + Sbjct: 1 MGFLTGKRALIVGVASKLSIASGIAAAMHREGAELAFTYQNDKLRGRVEEFASGWGSRPE 60 Query: 59 IVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHD 118 + CDVA+D+ I+ +FA LGK W D VHS+GFAPGDQLDGD+ TREGF+IAHD Sbjct: 61 LCFPCDVADDSQIEAVFAALGKHWDGLDIIVHSVGFAPGDQLDGDFTAVTTREGFRIAHD 120 Query: 119 ISSYSFVAMAKACRSMLN-PGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAM 177 IS+YSF+A+AKA R M+ +LLTLSYLGAER +PNYNVMG+AKASLEA VRY+A ++ Sbjct: 121 ISAYSFIALAKAGREMMKGRNGSLLTLSYLGAERTMPNYNVMGMAKASLEAGVRYLAGSL 180 Query: 178 GPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLS 237 G EG RVNA+SAGPIRTLAASGIK FRKMLA E TP+RR VTIE+VGN+ AFLCSDL+ Sbjct: 181 GAEGTRVNAVSAGPIRTLAASGIKSFRKMLAANERQTPLRRNVTIEEVGNAGAFLCSDLA 240 Query: 238 AGISGEVVHVDGGFSIAAMNELE 260 +GISGE+++VDGGF+ AM L+ Sbjct: 241 SGISGEILYVDGGFNTTAMGPLD 263 >4ZJU-A nrPDB Length = 275 Score = 350 bits (897), Expect = 5e-97, Method: Compositional matrix adjust. Identities = 169/258 (65%), Positives = 205/258 (79%), Gaps = 1/258 (0%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVL 61 G L+GKR L+ GVASKLSIAYGIAQA+HREGAELAFTY N+KLK RV+EFA Q GS +V Sbjct: 12 GLLAGKRFLIAGVASKLSIAYGIAQALHREGAELAFTYPNEKLKKRVDEFAEQFGSKLVF 71 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 CDVA DA ID FAEL K W DG VHSIGFAP LDGD+ + R+GFKIAHDIS+ Sbjct: 72 PCDVAVDAEIDNAFAELAKHWDGVDGVVHSIGFAPAHTLDGDFTDVTDRDGFKIAHDISA 131 Query: 122 YSFVAMAKACRSMLNPGSA-LLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 YSFVAMA+A + +L LLTL+Y G+ER +PNYNVMG+AKASLEA VRY+A+++G + Sbjct: 132 YSFVAMARAAKPLLQARQGCLLTLTYQGSERVMPNYNVMGMAKASLEAGVRYLASSLGVD 191 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 G+RVNAISAGPIRTLAASGIK FRKML E V P++R VTIE+VGN+A FLCS ++GI Sbjct: 192 GIRVNAISAGPIRTLAASGIKSFRKMLDANEKVAPLKRNVTIEEVGNAALFLCSPWASGI 251 Query: 241 SGEVVHVDGGFSIAAMNE 258 +GE+++VD GF+ M++ Sbjct: 252 TGEILYVDAGFNTVGMSQ 269 >5I9N-A nrPDB Length = 276 Score = 335 bits (860), Expect = 8e-93, Method: Compositional matrix adjust. Identities = 165/264 (62%), Positives = 207/264 (78%), Gaps = 2/264 (0%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 60 MGFL GKRIL+TG+ S SIAYGIA+A REGAELAFTY D+ K R+ EFAA+ GS++V Sbjct: 1 MGFLDGKRILLTGLLSNRSIAYGIAKACKREGAELAFTYVGDRFKDRITEFAAEFGSELV 60 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 CDVA+DA ID +FA L W DG VHSIGFAP + + GD+++ +TRE F+IAHDIS Sbjct: 61 FPCDVADDAQIDALFASLKTHWDSLDGLVHSIGFAPREAIAGDFLDGLTRENFRIAHDIS 120 Query: 121 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 +YSF A+AKA ML+ ++LLTLSYLGAERAIPNYN MGLAKA+LEA+VRY+A ++G + Sbjct: 121 AYSFPALAKAALPMLSDDASLLTLSYLGAERAIPNYNTMGLAKAALEASVRYLAVSLGAK 180 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 GVRVNAISAGPI+TLAASGIK F K+L E+ +P++R VTIE VGN+ AFL SDL++G+ Sbjct: 181 GVRVNAISAGPIKTLAASGIKSFGKILDFVESNSPLKRNVTIEQVGNAGAFLLSDLASGV 240 Query: 241 SGEVVHVDGGFS--IAAMNELELK 262 + EV+HVD GF+ + M LE K Sbjct: 241 TAEVMHVDSGFNAVVGGMAGLEEK 264 >4M89-A nrPDB Length = 261 Score = 322 bits (826), Expect = 7e-89, Method: Compositional matrix adjust. Identities = 157/258 (60%), Positives = 202/258 (78%), Gaps = 1/258 (0%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 60 MGFL GK+IL+TG+ S+ SIAYGIA+A +GAELAFTY DKL+ RV + AA+L S++V Sbjct: 1 MGFLQGKKILITGMISERSIAYGIAKACREQGAELAFTYVVDKLEERVRKMAAELDSELV 60 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 +CDVA D I+ +FA+LGK W DG VHSIGFAP + L GD++++++RE F AH+IS Sbjct: 61 FRCDVASDDEINQVFADLGKHWDGLDGLVHSIGFAPKEALSGDFLDSISREAFNTAHEIS 120 Query: 121 SYSFVAMAKACRSMLN-PGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 +YS A+AKA R M+ SA++ LSYLGA RAIPNYNVMG+AKASLEA +R+ A +G Sbjct: 121 AYSLPALAKAARPMMRGRNSAIVALSYLGAVRAIPNYNVMGMAKASLEAGIRFTAACLGK 180 Query: 180 EGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAG 239 EG+R N ISAGPI+TLAASGI DF K+L H A P+RR VTIE+VGN+AAFL SDLS+G Sbjct: 181 EGIRCNGISAGPIKTLAASGIADFGKLLGHVAAHNPLRRNVTIEEVGNTAAFLLSDLSSG 240 Query: 240 ISGEVVHVDGGFSIAAMN 257 I+GE+ +VDGG+SI A++ Sbjct: 241 ITGEITYVDGGYSINALS 258 >4J3F-A nrPDB Length = 280 Score = 318 bits (815), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 152/260 (58%), Positives = 200/260 (76%), Gaps = 2/260 (0%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 60 MGFL+GK+IL+TG+ S SIAYGIA+AMHREGAELAFTY + K RVE+ A+ V Sbjct: 21 MGFLAGKKILITGLLSNKSIAYGIAKAMHREGAELAFTYVG-QFKDRVEKLCAEFNPAAV 79 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 L CDV D I +F ELGKVW D VHSI FAP DQL+G++++ VTREGF IAHDIS Sbjct: 80 LPCDVISDQEIKDLFVELGKVWDGLDAIVHSIAFAPRDQLEGNFIDCVTREGFSIAHDIS 139 Query: 121 SYSFVAMAKACRSML-NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 +YSF A+AK RSM+ N ++++ L+Y+GAE+A+P+YN MG+AKASLEA VRY A A+G Sbjct: 140 AYSFAALAKEGRSMMKNRNASMVALTYIGAEKAMPSYNTMGVAKASLEATVRYTALALGE 199 Query: 180 EGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAG 239 +G++VNA+SAGPI+TLAASGI +F+KML + V+P+++ V I +VGN+ AFLCSD++ G Sbjct: 200 DGIKVNAVSAGPIKTLAASGISNFKKMLDYNAMVSPLKKNVDIMEVGNTVAFLCSDMATG 259 Query: 240 ISGEVVHVDGGFSIAAMNEL 259 I+GEVVHVD G+ +M + Sbjct: 260 ITGEVVHVDAGYHCVSMGNV 279 >5KOI-A nrPDB Length = 293 Score = 271 bits (694), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 132/259 (50%), Positives = 181/259 (69%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVL 61 G + GKR L+ GVA+ S+A+GIA+ + +GAELAFTYQ D L RV+ A Q+GSD VL Sbjct: 24 GLMQGKRGLIMGVANNHSLAWGIAKQLAAQGAELAFTYQGDALGKRVKPLAEQVGSDFVL 83 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 CDV + A++D +F E+ K W D VH+IGF+ +L G Y + TRE F IS+ Sbjct: 84 PCDVEDIATVDAVFEEIEKKWGGLDFLVHAIGFSDKTELKGRYADVTTRENFSRTMVISA 143 Query: 122 YSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 YSF +A+ ++ G ++LTL+Y G+ R IPNYNVMG+AKA+LEA VRY+A GP+G Sbjct: 144 YSFTEVAQRAEKLMKDGGSILTLTYGGSTRTIPNYNVMGVAKAALEAMVRYLAADYGPQG 203 Query: 182 VRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGIS 241 +RVNAISAGP+RTLA +GI D R + ++ +P+RRTV I+DVG SA +L SDLS+G++ Sbjct: 204 IRVNAISAGPVRTLAGAGIGDARAIFSYQRRNSPLRRTVDIDDVGKSAVYLLSDLSSGVT 263 Query: 242 GEVVHVDGGFSIAAMNELE 260 GE+ VD G++I +M LE Sbjct: 264 GEIHFVDSGYNIVSMPTLE 282 >5TF4-A nrPDB Length = 274 Score = 263 bits (673), Expect = 4e-71, Method: Compositional matrix adjust. Identities = 130/259 (50%), Positives = 182/259 (70%), Gaps = 1/259 (0%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVL 61 G L GKR L+ G+A+ SIA+GIA+ GAELAFTYQ + +K RVE A ++ + Sbjct: 8 GLLYGKRGLILGLANNRSIAWGIAKTASSAGAELAFTYQGEAMKKRVEPLAEEVKGFVCG 67 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 CDV++ ASID +F + K W K D VH+IGF+ ++L G YV+ ++ F + +IS Sbjct: 68 HCDVSDSASIDAVFNTIEKKWGKLDFLVHAIGFSDKEELSGRYVD-ISESNFMMTMNISV 126 Query: 122 YSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 YS A+ K +++ G ++LTL+Y GAE+ +PNYNVMG+AKA+LEA+V+Y+A +GP+ Sbjct: 127 YSLTALTKRAEKLMSDGGSILTLTYYGAEKVVPNYNVMGVAKAALEASVKYLAVDLGPKH 186 Query: 182 VRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGIS 241 +RVNAISAGPI+TLAASGI DFR +L E P+RRTVTIE+VG+SA +L SDLS ++ Sbjct: 187 IRVNAISAGPIKTLAASGIGDFRYILKWNEYNAPLRRTVTIEEVGDSALYLLSDLSRSVT 246 Query: 242 GEVVHVDGGFSIAAMNELE 260 GEV HVD G++I M ++ Sbjct: 247 GEVHHVDSGYNIIGMKAVD 265 >2P91-A nrPDB Length = 285 Score = 263 bits (673), Expect = 5e-71, Method: Compositional matrix adjust. Identities = 132/265 (49%), Positives = 180/265 (67%), Gaps = 4/265 (1%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 60 MG L GKR L+TGVA++ SIAYGIA++ HREGA+LAFTY KL+ RV E A GSD+V Sbjct: 16 MGLLEGKRALITGVANERSIAYGIAKSFHREGAQLAFTYATPKLEKRVREIAKGFGSDLV 75 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 ++CDV+ D I + L + W D VHSI +AP ++ G ++ +REGFKIA DIS Sbjct: 76 VKCDVSLDEDIKNLKKFLEENWGSLDIIVHSIAYAPKEEFKGGVIDT-SREGFKIAMDIS 134 Query: 121 SYSFVAMAKACRSMLN-PGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 YS +A+ + ++ A++TLSY GAE+ +P+YNVMG+AKA+LE+ VRY+A + Sbjct: 135 VYSLIALTRELLPLMEGRNGAIVTLSYYGAEKVVPHYNVMGIAKAALESTVRYLAYDIAK 194 Query: 180 EGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAG 239 G R+NAISAGP++TLAA I F ++ H V P + +TIEDVG++A FLCSD + Sbjct: 195 HGHRINAISAGPVKTLAAYSITGFHLLMEHTTKVNPFGKPITIEDVGDTAVFLCSDWARA 254 Query: 240 ISGEVVHVDGGFSIAAM--NELELK 262 I+GEVVHVD G+ I + E E+K Sbjct: 255 ITGEVVHVDNGYHIMGVFGREEEIK 279 >3GRK-A nrPDB Length = 293 Score = 261 bits (668), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 131/259 (50%), Positives = 177/259 (68%), Gaps = 1/259 (0%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVL 61 G L GKR L+ GVA+ SIA+GIA+A GAELAFTYQ D LK RVE A +LG+ + Sbjct: 27 GLLQGKRGLILGVANNRSIAWGIAKAAREAGAELAFTYQGDALKKRVEPLAEELGAFVAG 86 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 CDVA+ ASID +F L K W K D VH+IGF+ D+L G Y++ + F IS Sbjct: 87 HCDVADAASIDAVFETLEKKWGKLDFLVHAIGFSDKDELTGRYID-TSEANFTNTMLISV 145 Query: 122 YSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 YS A+++ ++ G ++LTL+Y GAE+ +PNYNVMG+AKA+LEA+V+Y+A +GP+ Sbjct: 146 YSLTAVSRRAEKLMADGGSILTLTYYGAEKVMPNYNVMGVAKAALEASVKYLAVDLGPQN 205 Query: 182 VRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGIS 241 +RVNAISAGPI+TLAASGI DFR +L E P+RRTVTI++VG+ + SDLS ++ Sbjct: 206 IRVNAISAGPIKTLAASGIGDFRYILKWNEYNAPLRRTVTIDEVGDVGLYFLSDLSRSVT 265 Query: 242 GEVVHVDGGFSIAAMNELE 260 GEV H D G+ + M ++ Sbjct: 266 GEVHHADSGYHVIGMKAVD 284 >3OIG-A nrPDB Length = 266 Score = 260 bits (665), Expect = 3e-70, Method: Compositional matrix adjust. Identities = 133/258 (51%), Positives = 179/258 (69%), Gaps = 4/258 (1%) Query: 1 MGF-LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSD- 58 M F L G+ I+V GVA+K SIA+GIA+++H GA L FTY ++L+ V E A L + Sbjct: 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRND 60 Query: 59 -IVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAH 117 I+L CDV DA I+T FA + + G H I FA ++L G+Y+N R+GF +AH Sbjct: 61 SIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLN-TNRDGFLLAH 119 Query: 118 DISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAM 177 +ISSYS A+ KA R M+ G +++TL+YLG E +PNYNVMG+AKASL+A+V+Y+A + Sbjct: 120 NISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADL 179 Query: 178 GPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLS 237 G E +RVN+ISAGPIRTL+A GI DF +L E P+RRT T E+VG++AAFL SD+S Sbjct: 180 GKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMS 239 Query: 238 AGISGEVVHVDGGFSIAA 255 GI+GE +HVD GF I A Sbjct: 240 RGITGENLHVDSGFHITA 257 >5YCX-A nrPDB Length = 266 Score = 242 bits (618), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 120/258 (46%), Positives = 171/258 (66%), Gaps = 3/258 (1%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQL--GSD 58 M L GK +V GVA++ SIA+GIA+++H GA+L FTY ++L+ V E A L Sbjct: 3 MELLQGKTFVVMGVANQRSIAWGIARSLHNAGAKLIFTYAGERLERNVRELADTLEGQES 62 Query: 59 IVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHD 118 +VL CDV D + F + + G H I FA D L G++V+ +R+GF +A + Sbjct: 63 LVLPCDVTNDEELTACFETIKQEVGTIHGVAHCIAFANRDDLKGEFVD-TSRDGFLLAQN 121 Query: 119 ISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMG 178 IS++S A+A+ + ++ G +LTL+YLG ER + NYNVMG+AKASLEA+V+Y+AN +G Sbjct: 122 ISAFSLTAVAREAKKVMTEGGNILTLTYLGGERVVKNYNVMGVAKASLEASVKYLANDLG 181 Query: 179 PEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSA 238 G+RVNAISAGPIRTL+A G+ DF +L E P+RRT T E+VG++A FL SDL+ Sbjct: 182 QHGIRVNAISAGPIRTLSAKGVGDFNSILREIEERAPLRRTTTQEEVGDTAVFLFSDLAR 241 Query: 239 GISGEVVHVDGGFSIAAM 256 G++GE +HVD G+ I + Sbjct: 242 GVTGENIHVDSGYHILGL 259 >2YW9-A nrPDB Length = 261 Score = 232 bits (592), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 113/257 (43%), Positives = 171/257 (66%), Gaps = 2/257 (0%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 LSGK+ LV GV ++ S+ + IA + GAE+A +YQ ++L+ E+ A LG ++ + Sbjct: 6 LSGKKALVMGVTNQRSLGFAIAAKLKEAGAEVALSYQAERLRPEAEKLAEALGGALLFRA 65 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 DV +D +D +FA + + + D VH+I FAP + ++G Y++ R+ + +A ++S+YS Sbjct: 66 DVTQDEELDALFAGVKEAFGGLDYLVHAIAFAPREAMEGRYID-TRRQDWLLALEVSAYS 124 Query: 124 FVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVR 183 VA+A+ +L G ++TL+Y +E+ +P YNVM +AKA+LEA+VRY+A +GP+GVR Sbjct: 125 LVAVARRAEPLLREGGGIVTLTYYASEKVVPKYNVMAIAKAALEASVRYLAYELGPKGVR 184 Query: 184 VNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGE 243 VNAISAGP+RT+AA I F KM P+RR +T E+VGN FL S L++GI+GE Sbjct: 185 VNAISAGPVRTVAARSIPGFTKMYDRVAQTAPLRRNITQEEVGNLGLFLLSPLASGITGE 244 Query: 244 VVHVDGGFSIAAMNELE 260 VV+VD G+ I M ELE Sbjct: 245 VVYVDAGYHIMGM-ELE 260 >2PD3-A nrPDB Length = 275 Score = 230 bits (587), Expect = 4e-61, Method: Compositional matrix adjust. Identities = 120/262 (45%), Positives = 174/262 (66%), Gaps = 1/262 (0%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 60 MGFL GK+ L+ GVA+ SIAYGIAQ+ +GA LAFTY N+ L+ RV A +L S V Sbjct: 1 MGFLKGKKGLIVGVANNKSIAYGIAQSCFNQGATLAFTYLNESLEKRVRPIAQELNSPYV 60 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 + DV+++ +++ + K D VHS+ FAP + L+G + ++ F A +IS Sbjct: 61 YELDVSKEEHFKSLYNSVKKDLGSLDFIVHSVAFAPKEALEGSLLE-TSKSAFNTAMEIS 119 Query: 121 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 YS + + + +LN G+++LTLSYLG+ + + +YNVMGLAKA+LE+ VRY+A +G Sbjct: 120 VYSLIELTNTLKPLLNNGASVLTLSYLGSTKYMAHYNVMGLAKAALESAVRYLAVDLGKH 179 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 +RVNA+SAGPIRTLA+SGI DFR +L E P+R+ V++E+VGN+ +L S LS+G+ Sbjct: 180 HIRVNALSAGPIRTLASSGIADFRMILKWNEINAPLRKNVSLEEVGNAGMYLLSSLSSGV 239 Query: 241 SGEVVHVDGGFSIAAMNELELK 262 SGEV VD G+ + M +E K Sbjct: 240 SGEVHFVDAGYHVMGMGAVEEK 261 >3K2E-A nrPDB Length = 296 Score = 230 bits (587), Expect = 4e-61, Method: Compositional matrix adjust. Identities = 111/258 (43%), Positives = 170/258 (65%), Gaps = 1/258 (0%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQ 62 + GK+ ++ GVA+ S+A+GIA+A+ +GAE+A TY ++ K RV+ A LG + + Sbjct: 27 LMEGKKGVIIGVANDKSLAWGIAKAVCAQGAEVALTYLSETFKKRVDPLAESLGVKLTVP 86 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSY 122 CDV++ S+D MF L + W D VH++ F+ ++L G YV+ + F + IS Y Sbjct: 87 CDVSDAESVDNMFKVLAEEWGSLDFVVHAVAFSDKNELKGRYVDT-SLGNFLTSMHISCY 145 Query: 123 SFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGV 182 SF +A ++ G ++LTLSY GAE+ +P+YNVMG+ KA+LEA+V+Y+A +G + + Sbjct: 146 SFTYIASKAEPLMTNGGSILTLSYYGAEKVVPHYNVMGVCKAALEASVKYLAVDLGKQQI 205 Query: 183 RVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISG 242 RVNAISAGP+RTLA+SGI DF +L + +P+RR T++DVG +A +L SDL G +G Sbjct: 206 RVNAISAGPVRTLASSGISDFHYILTWNKYNSPLRRNTTLDDVGGAALYLLSDLGRGTTG 265 Query: 243 EVVHVDGGFSIAAMNELE 260 E VHVD G+ + M ++ Sbjct: 266 ETVHVDCGYHVVGMKSVD 283 >4ALL-A nrPDB Length = 277 Score = 219 bits (557), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 110/250 (44%), Positives = 162/250 (64%), Gaps = 3/250 (1%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSD--IVL 61 L K ++ G+A+K SIA+G+A+ + + GA+L FTY+ ++ + +E+ QL + Sbjct: 25 LENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLY 84 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 Q DV D + F ++GK DG HSI FA + L G + + +REGF +A DISS Sbjct: 85 QIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRF-SETSREGFLLAQDISS 143 Query: 122 YSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 YS +A + ++ G +++ +YLG E A+ NYNVMG+AKASLEANV+Y+A +GP+ Sbjct: 144 YSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDN 203 Query: 182 VRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGIS 241 +RVNAISAGPIRTL+A G+ F +L E P++R V +VG +AA+L SDLS+G++ Sbjct: 204 IRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVT 263 Query: 242 GEVVHVDGGF 251 GE +HVD GF Sbjct: 264 GENIHVDSGF 273 >4NK4-A nrPDB Length = 301 Score = 215 bits (547), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 104/256 (40%), Positives = 168/256 (65%), Gaps = 1/256 (0%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 60 + L GKR L+ GVA+ SIA+GIA+ +H GA+LAF+YQ + + R++ A + SD + Sbjct: 36 INILKGKRGLIMGVANDHSIAWGIAKVLHSAGAQLAFSYQGESIGKRLKPLALTVDSDFM 95 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 + C+V + +S+D +F + + W D VHSI F+ ++L G Y N +R+ F +S Sbjct: 96 IPCNVEDPSSMDLLFERIKERWETLDFVVHSIAFSDKNELRGPYYN-TSRDNFIQTMLVS 154 Query: 121 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 +SF + + ++ G A++TL+Y G+ R +PNYN M AK++LE++ +Y+A G Sbjct: 155 CFSFTEIVRRAAQLMPHGGAMITLTYGGSMRVVPNYNAMAPAKSALESSTKYLACDYGGM 214 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 +R+NAISAGP+RTLA + I + R + A + +P++RTV++ED+GNSA +L S LS G+ Sbjct: 215 NIRINAISAGPVRTLAGASISNGRDIAAWSKENSPLKRTVSLEDIGNSALYLLSYLSNGV 274 Query: 241 SGEVVHVDGGFSIAAM 256 +GE+ +VD G++I AM Sbjct: 275 TGEIHYVDCGYNIVAM 290 >4OYR-A nrPDB Length = 289 Score = 115 bits (289), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 91/274 (33%), Positives = 141/274 (51%), Gaps = 38/274 (13%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDI-V 60 G L GKRILV+G+ + SIA+ IA+ +GA+L T D+L+ ++ +L + + Sbjct: 23 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLT-GFDRLR-LIQRITDRLPAKAPL 80 Query: 61 LQCDVAED---ASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLD-GDYVNAVTREGFKIA 116 L+ DV + AS+ E K DG VHSIGF P + + +A + K Sbjct: 81 LELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGI 140 Query: 117 HDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANA 176 H IS+YS+ +MAKA ++NPG +++ + + RA+P YN M +AK++LE+ R++A Sbjct: 141 H-ISAYSYASMAKALLPIMNPGGSIVGMDF-DPSRAMPAYNWMTVAKSALESVNRFVARE 198 Query: 177 MGPEGVRVNAISAGPIRTLAASGI-------------------KDFRKMLA-HCEAVTPI 216 G GVR N ++AGPIRTLA S I D R + + + TP+ Sbjct: 199 AGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPV 258 Query: 217 RRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGG 250 +TV L SD +G++++ DGG Sbjct: 259 AKTVCA---------LLSDWLPATTGDIIYADGG 283 >2NTV-A nrPDB Length = 268 Score = 111 bits (278), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 87/269 (32%), Positives = 140/269 (52%), Gaps = 24/269 (8%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDI-V 60 G L GKRILV+G+ + SIA+ IA+ GA+L T D+L+ ++ A +L + Sbjct: 2 GLLEGKRILVSGIITDSSIAFHIAKVAQEAGAQLVLT-GFDRLR-LIQRIADRLPDKAPL 59 Query: 61 LQCDVAEDASIDTM----FAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIA 116 ++ DV + + T+ AE+G+ K DG VHSIGF P + + E Sbjct: 60 IELDVQNEEHLATLAERVTAEIGEG-NKLDGVVHSIGFMPQTGMGTNQFFDAPYEDVSKG 118 Query: 117 HDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANA 176 IS+YS+ ++AKA ++N G +++ + + RA+P YN M +AK++LE+ R++A Sbjct: 119 IHISTYSYASLAKALLLIMNSGGSIVGMDF-DPTRAMPAYNWMTVAKSALESVNRFVARE 177 Query: 177 MGPEGVRVNAISAGPIRTLAASGI----------KDFRKMLAHCEAVTPIRRTVTIEDVG 226 G GVR N ++AGPIRTLA S I + + + PI ++D Sbjct: 178 AGKYGVRSNLVAAGPIRTLAMSAIVGGAFGEEAGAQMQLLEEGWDQRAPI--GWNMKDPT 235 Query: 227 NSAAFLCSDLSAGI---SGEVVHVDGGFS 252 A +C+ LS + +G +++ DGG S Sbjct: 236 PVAKTVCALLSEWLPATTGSIIYADGGAS 264 >1ENP-A nrPDB Length = 312 Score = 110 bits (274), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 85/285 (29%), Positives = 138/285 (48%), Gaps = 40/285 (14%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAF--------TYQNDKLKGRVE------ 49 L GKR + G+A + +A+++ GAE+ ++ +G+ + Sbjct: 16 LRGKRAFIAGIADDNGYGWAVAKSLAAAGAEILVGTWVPALNIFETSLRRGKFDQSRVLP 75 Query: 50 -----EFAAQLGSDIVLQC--DVAEDASIDTMFAELGKVWP-------------KFDGFV 89 E D V DV ED + +A W D V Sbjct: 76 DGSLMEIKKVYPLDAVFDNPEDVPEDVKANKRYAGSSN-WTVQEAAECVRQDFGSIDILV 134 Query: 90 HSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGA 149 HS+ A G ++ + +R+G+ A SSYSFV++ ++NPG A ++L+Y+ + Sbjct: 135 HSL--ANGPEVSKPLLE-TSRKGYLAAISASSYSFVSLLSHFLPIMNPGGASISLTYIAS 191 Query: 150 ERAIPNYNV-MGLAKASLEANVRYMANAMG-PEGVRVNAISAGPIRTLAASGIKDFRKML 207 ER IP Y M AKA+LE++ R +A G + +RVN ISAGP+ + AA I M+ Sbjct: 192 ERIIPGYGGGMSSAKAALESDTRVLAFEAGRKQNIRVNTISAGPLGSRAAKAIGFIDTMI 251 Query: 208 AHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFS 252 + PI++T+T ++VGN+AAFL S L++ I+G ++VD G + Sbjct: 252 EYSYNNAPIQKTLTADEVGNAAAFLVSPLASAITGATIYVDNGLN 296 >2O2S-A nrPDB Length = 315 Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 92/293 (31%), Positives = 139/293 (47%), Gaps = 52/293 (17%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAF--------TYQNDKLKGRVEE----- 50 L G+ V GVA + IA+ + GA +A +Q GR++E Sbjct: 7 LRGQTAFVAGVADSHGYGWAIAKHLASAGARVALGTWPPVLGLFQKSLQSGRLDEDRKLP 66 Query: 51 ------FAAQLGSDIVLQC--DVAEDASIDTMFA----------------ELGKVWPKFD 86 FA D DV +D + +A +LG + D Sbjct: 67 DGSLIEFAGVYPLDAAFDKPEDVPQDIKDNKRYAGVDGYTIKEVAVKVKQDLGNI----D 122 Query: 87 GFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSY 146 VHS+ A G ++ + +R+G+ A S+YSFV++ + ++N G + +TLSY Sbjct: 123 ILVHSL--ANGPEVTKPLLE-TSRKGYLAASSNSAYSFVSLLQHFGPIMNEGGSAVTLSY 179 Query: 147 LGAERAIPNY-NVMGLAKASLEANVRYMANAMGPE-GVRVNAISAGPIRTLAASGI---- 200 L AER +P Y M AKA+LE++ R +A G + GVRVNAISAGP+++ AAS I Sbjct: 180 LAAERVVPGYGGGMSSAKAALESDTRTLAWEAGQKYGVRVNAISAGPLKSRAASAIGKSG 239 Query: 201 -KDF-RKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGF 251 K F + + P+RR + +DVG +A FL S L+ +SG ++VD G Sbjct: 240 EKSFIDYAIDYSYNNAPLRRDLHSDDVGGAALFLLSPLARAVSGVTLYVDNGL 292 >4Q9N-A nrPDB Length = 298 Score = 97.4 bits (241), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 60/186 (32%), Positives = 108/186 (58%), Gaps = 5/186 (2%) Query: 70 SIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAK 129 ++ + ++ K + D VHS+ +P ++ ++ +R+G+ A SSYSF+++ Sbjct: 105 TVSEVVEQVKKHFGHIDILVHSLANSP--EIAKPLLD-TSRKGYLAALSTSSYSFISLLS 161 Query: 130 ACRSMLNPGSALLTLSYLGAERAIPNYNV-MGLAKASLEANVRYMANAMGPE-GVRVNAI 187 ++N G++ ++L+YL + RA+P Y M AKA+LE++ + +A G GVRVN I Sbjct: 162 HFGPIMNAGASTISLTYLASMRAVPGYGGGMNAAKAALESDTKVLAWEAGRRWGVRVNTI 221 Query: 188 SAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHV 247 SAGP+ + A I +M+ + + P+ + E VG +AAFL S L++ I+GE ++V Sbjct: 222 SAGPLASRAGKAIGFIERMVDYYQDWAPLPSPMEAEQVGAAAAFLVSPLASAITGETLYV 281 Query: 248 DGGFSI 253 D G ++ Sbjct: 282 DHGANV 287 >3OIC-A nrPDB Length = 258 Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 58/201 (28%), Positives = 102/201 (50%), Gaps = 9/201 (4%) Query: 59 IVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIG---FAPGDQLDGDYVNAVTREGFKI 115 +V++ +V + A I MF ++ + + + D FV++ P +L+ T + + Sbjct: 57 LVVKANVGQPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELEE------THWDWTM 110 Query: 116 AHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMAN 175 + + F A A N G ++++S LG+ R + NY +G++KA+LEA RY+A Sbjct: 111 NINAKALLFCAQEAAKLMEKNGGGHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAV 170 Query: 176 AMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSD 235 + P+ + VNA+S G I T A + +L TP R V I+D+ ++ FL S Sbjct: 171 ELSPKQIIVNAVSGGAIDTDALKHFPNREDLLEDARQNTPAGRMVEIKDMVDTVEFLVSS 230 Query: 236 LSAGISGEVVHVDGGFSIAAM 256 + I G+ + VDGG S+ + Sbjct: 231 KADMIRGQTIIVDGGRSLLVL 251 >2O2Y-A nrPDB Length = 349 Score = 84.3 bits (207), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 57/237 (24%), Positives = 115/237 (48%), Gaps = 48/237 (20%) Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 + ++ ++ +I+ + + + + K + VHS+ A ++ D +N +R+G+ A SS Sbjct: 103 RYNMLQNYTIEDVANLIHQKYGKINMLVHSL--ANAKEVQKDLLN-TSRKGYLDALSKSS 159 Query: 122 YSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNY-NVMGLAKASLEANVRYMANAMGPE 180 YS +++ K +++ P S++++L+Y +++ +P Y M AKA+LE++ R +A +G Sbjct: 160 YSLISLCKYFVNIMKPQSSIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLGRN 219 Query: 181 -GVRVNAISAGPIRTLAASGIKDFRKM--------------------------------- 206 +R+N ISAGP+++ AA+ I Sbjct: 220 YNIRINTISAGPLKSRAATAINKLNNTYENNTNQNKNRNSHDVHNIMNNSGEKEEKKNSA 279 Query: 207 ----------LAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSI 253 + + E P+R+ + D+G+ A+FL S S I+G+ ++VD G +I Sbjct: 280 SQNYTFIDYAIEYSEKYAPLRQKLLSTDIGSVASFLLSRESRAITGQTIYVDNGLNI 336 >3F4B-A nrPDB Length = 323 Score = 84.0 bits (206), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 55/196 (28%), Positives = 104/196 (53%), Gaps = 27/196 (13%) Query: 82 WPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSAL 141 + K VHS+ A G ++ ++ +R+G+ A SSYS +++ K +N G ++ Sbjct: 118 YGKISMLVHSL--ANGREVQKSLLD-TSRDGYLDAISKSSYSLISLCKHFCKFMNSGGSV 174 Query: 142 LTLSYLGAERAIPNYNV-MGLAKASLEANVRYMANAMGPE-GVRVNAISAGPIRTLAASG 199 ++L+Y +++ +P Y M AKA+LE++ R +A +G + +R+N ISAGP+++ AA+ Sbjct: 175 VSLTYQASQKVVPGYGGGMSSAKAALESDTRVLAYYLGRKYNIRINTISAGPLKSRAATA 234 Query: 200 IKDFRKM----------------------LAHCEAVTPIRRTVTIEDVGNSAAFLCSDLS 237 I F + + E P+++ + DVG+ A+FL S S Sbjct: 235 INKFNNNQKNNMNSSGETDKQNYSFIDYAIDYSEKYAPLKKKLLSTDVGSVASFLLSKES 294 Query: 238 AGISGEVVHVDGGFSI 253 + ++G+ ++VD G +I Sbjct: 295 SAVTGQTIYVDNGLNI 310 >2PTG-A nrPDB Length = 319 Score = 79.3 bits (194), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 63/176 (35%), Positives = 101/176 (57%), Gaps = 11/176 (6%) Query: 84 KFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLT 143 + D VHS+ A G ++ + +R+G+ A SSYSFV++ + ++ G + L Sbjct: 133 QIDILVHSL--ANGPEVTKPLLQ-TSRKGYLAAVSSSSYSFVSLLQHFLPLMKEGGSALA 189 Query: 144 LSYLGAERAIPNY-NVMGLAKASLEANVRYMANAMG-PEGVRVNAISAGPIRTLAASGI- 200 LSY+ +E+ IP Y M AKA+LE++ R +A G VRVN ISAGP+++ AAS I Sbjct: 190 LSYIASEKVIPGYGGGMSSAKAALESDCRTLAFEAGRARAVRVNCISAGPLKSRAASAIG 249 Query: 201 ----KDFRKM-LAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGF 251 K F + + + EA P+++ + +DVG +A FL S L+ ++G ++VD G Sbjct: 250 KAGDKTFIDLAIDYSEANAPLQKELESDDVGRAALFLLSPLARAVTGATLYVDNGL 305 >1AHH-A nrPDB Length = 255 Score = 74.3 bits (181), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 73/257 (28%), Positives = 120/257 (46%), Gaps = 26/257 (10%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSD-IVLQ 62 L GK ++TG + I IA GA + + N V + QLG + Sbjct: 9 LDGKCAIITGAGA--GIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACR 66 Query: 63 CDVAEDASI----DTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHD 118 CD+ + + D ++LGKV D V++ G D + F+ A++ Sbjct: 67 CDITSEQELSALADFAISKLGKV----DILVNNAGGGGPKPFD------MPMADFRRAYE 116 Query: 119 ISSYSFVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANA 176 ++ +SF +++ + N G +LT++ + AE N +KA+ VR MA Sbjct: 117 LNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFD 176 Query: 177 MGPEGVRVNAISAGPIRTLAASGI---KDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLC 233 +G + +RVN I+ G I T A + + +KML H TPIRR +D+ N+A FLC Sbjct: 177 LGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQH----TPIRRLGQPQDIANAALFLC 232 Query: 234 SDLSAGISGEVVHVDGG 250 S ++ +SG+++ V GG Sbjct: 233 SPAASWVSGQILTVSGG 249 >1W73-A nrPDB Length = 302 Score = 70.5 bits (171), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 64/224 (28%), Positives = 108/224 (48%), Gaps = 30/224 (13%) Query: 42 DKLKGRVEEFAAQLGSDI-VLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQL 100 D LK E+ ++Q G+ + +QCDV + + +EL KV + +++ Sbjct: 61 DVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAA------- 113 Query: 101 DGDYVNAVTR---EGFKIAHDI--SSYSFVAMAKACRSM-LNPGSALLTLSYLGAER--- 151 G++++ R +K DI + +FV + + + G+A L+++ + AE Sbjct: 114 -GNFISPTERLSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSG 172 Query: 152 -AIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKD----FRKM 206 +P+ + AKA +EA + +A G G+R N I GPI+T A D F K Sbjct: 173 FVVPSAS----AKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKE 228 Query: 207 LAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGG 250 + P R T+E++ N AAFLCSD ++ I+G V+ DGG Sbjct: 229 MI---GRIPCGRLGTVEELANLAAFLCSDYASWINGAVIKFDGG 269 >3D3W-A nrPDB Length = 244 Score = 70.1 bits (170), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 71/260 (27%), Positives = 121/260 (46%), Gaps = 33/260 (12%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQ 62 FL+G+R+LVTG I G QA+H GA + V A L S +V + Sbjct: 4 FLAGRRVLVTGAGK--GIGRGTVQALHATGARVV----------AVSRTQADLDS-LVRE 50 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNA-------VTREGFKI 115 C E +D LG W + + S+G P D L + A VT+E F Sbjct: 51 CPGIEPVCVD-----LGD-WEATERALGSVG--PVDLLVNNAAVALLQPFLEVTKEAFDR 102 Query: 116 AHDISSYSFVAMAK-ACRSMLNPG--SALLTLSYLGAERAIPNYNVMGLAKASLEANVRY 172 + +++ + + +++ R ++ G A++ +S ++RA+ N++V K +L+ + Sbjct: 103 SFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKV 162 Query: 173 MANAMGPEGVRVNAISAGPIRT-LAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAF 231 MA +GP +RVNA++ + T + + D K + P+ + +E V N+ F Sbjct: 163 MALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRI-PLGKFAEVEHVVNAILF 221 Query: 232 LCSDLSAGISGEVVHVDGGF 251 L SD S +G + V+GGF Sbjct: 222 LLSDRSGMTTGSTLPVEGGF 241 >4MOW-A nrPDB Length = 256 Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 70/259 (27%), Positives = 118/259 (45%), Gaps = 18/259 (6%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKL--KGRVEEFAAQLGSD 58 M L+GK +VTG ASK I IA+A+ EGA + Y + K V G Sbjct: 9 MSKLAGKVAIVTG-ASK-GIGAAIAKALADEGAAVVVNYASSKAGADAVVSAITEAGGRA 66 Query: 59 IVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIG---FAPGDQLDGDYVNAVTREGFKI 115 + + DV++ A + + + + D V++ G FAP + A+T E ++ Sbjct: 67 VAVGGDVSKAADAQRIVDTAIETYGRLDVLVNNSGVYEFAP--------IEAITEEHYRR 118 Query: 116 AHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMAN 175 D + + + +A L G++++ +S + P V K +++A +A Sbjct: 119 QFDTNVFGVLLTTQAAVKHLGEGASIINISSVVTSITPPASAVYSGTKGAVDAITGVLAL 178 Query: 176 AMGPEGVRVNAISAGPIRT--LAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLC 233 +GP +RVNAI+ G I T ++GI + A TP+ R D+ + A FL Sbjct: 179 ELGPRKIRVNAINPGMIVTEGTHSAGIIG-SDLEAQVLGQTPLGRLGEPNDIASVAVFLA 237 Query: 234 SDLSAGISGEVVHVDGGFS 252 SD + ++GE + V GG + Sbjct: 238 SDDARWMTGEHLVVSGGLN 256 >1O5I-A nrPDB Length = 249 Score = 61.6 bits (148), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 60/244 (24%), Positives = 109/244 (44%), Gaps = 28/244 (11%) Query: 14 VASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDT 73 +A+ I +A + +EGAE+ +N EE + G V+ CD+ +D +D Sbjct: 25 LAASRGIGRAVADVLSQEGAEVTICARN-------EELLKRSGHRYVV-CDLRKD--LDL 74 Query: 74 MFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRS 133 +F ++ +V D V + G P + + +T E FK A D F+ M K R+ Sbjct: 75 LFEKVKEV----DILVLNAG-GP----KAGFFDELTNEDFKEAID---SLFLNMIKIVRN 122 Query: 134 ML-----NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAIS 188 L ++ ++ I N A+ +L ++ ++ + P G+ VN ++ Sbjct: 123 YLPAMKEKGWGRIVAITSFSVISPIENLYTSNSARMALTGFLKTLSFEVAPYGITVNCVA 182 Query: 189 AGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVD 248 G T + K E+ P+RR E++ + AFLCS+ ++ ++G+ + VD Sbjct: 183 PGWTETERVKELLSEEKK-KQVESQIPMRRMAKPEEIASVVAFLCSEKASYLTGQTIVVD 241 Query: 249 GGFS 252 GG S Sbjct: 242 GGLS 245 >2PNF-A nrPDB Length = 248 Score = 60.8 bits (146), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 70/258 (27%), Positives = 114/258 (44%), Gaps = 25/258 (9%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFT-YQNDKLKGRVEEFAAQLGSDIV-L 61 L GK LVTG S I IA+ + G+ + T ++ K EE A + G + Sbjct: 5 LQGKVSLVTG--STRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGV 62 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIG------FAPGDQLDGDYVNAVTREGFKI 115 + ++ + SI+ F E+ + D V++ G F LD + V V G Sbjct: 63 EMNLLSEESINKAFEEIYNLVDGIDILVNNAGITRDKLFLRMSLLDWEEVLKVNLTG--- 119 Query: 116 AHDISSYSFVAMAKACRSMLNP--GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYM 173 +F+ + R M+ G + S +G + N KA L + + Sbjct: 120 -------TFLVTQNSLRKMIKQRWGRIVNISSVVGFTGNVGQVN-YSTTKAGLIGFTKSL 171 Query: 174 ANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLC 233 A + P V VNA++ G I T + + + K + E + P+ R + E+V N FLC Sbjct: 172 AKELAPRNVLVNAVAPGFIETDMTAVLSEEIKQ-KYKEQI-PLGRFGSPEEVANVVLFLC 229 Query: 234 SDLSAGISGEVVHVDGGF 251 S+L++ I+GEV+HV+GG Sbjct: 230 SELASYITGEVIHVNGGM 247 >1CYD-A nrPDB Length = 244 Score = 60.8 bits (146), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 70/260 (26%), Positives = 108/260 (41%), Gaps = 35/260 (13%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAEL-AFTYQNDKLKGRVEEFAAQLGSDIVLQ 62 SG R LVTG I +A+H GA++ A T N L +E Sbjct: 5 FSGLRALVTGAGK--GIGRDTVKALHASGAKVVAVTRTNSDLVSLAKE------------ 50 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNA-------VTREGFKI 115 C E +D LG W + + IG P D L + VT+E F Sbjct: 51 CPGIEPVCVD-----LGD-WDATEKALGGIG--PVDLLVNNAALVIMQPFLEVTKEAFDR 102 Query: 116 AHDISSYSFVAMAK-ACRSMLN---PGSALLTLSYLGAERAIPNYNVMGLAKASLEANVR 171 + ++ S +++ R M+N PGS ++ +S + A PN K ++ + Sbjct: 103 SFSVNLRSVFQVSQMVARDMINRGVPGS-IVNVSSMVAHVTFPNLITYSSTKGAMTMLTK 161 Query: 172 YMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAF 231 MA +GP +RVN+++ + T + + + P+R+ +EDV NS F Sbjct: 162 AMAMELGPHKIRVNSVNPTVVLTDMGKKVSADPEFARKLKERHPLRKFAEVEDVVNSILF 221 Query: 232 LCSDLSAGISGEVVHVDGGF 251 L SD SA SG + VD G+ Sbjct: 222 LLSDRSASTSGGGILVDAGY 241 >6CI9-A nrPDB Length = 259 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 64/252 (25%), Positives = 107/252 (42%), Gaps = 15/252 (5%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN-DKLKGRVEEFAAQLGSDIVLQ 62 L G+ +VTG SK I GIA+ G ++ T +N D L V + + G ++ Sbjct: 7 LEGRSAIVTG-GSK-GIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVR 64 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDG---DYVNAVTREGFKIAHDI 119 DV + AE D + G P +L+ D + V FK Sbjct: 65 ADVTDPEDARRTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFK----- 119 Query: 120 SSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 + V A + G ++T S G P ++ G +KA+ +R A + P Sbjct: 120 GTVYIVQAALQALTASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAMELAP 179 Query: 180 EGVRVNAISAGPIRTLAASGIKDF-RKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSA 238 + + +NA+ G I T G+ + + L + P R ++ D+GN+A F +D +A Sbjct: 180 KKITINAVLPGNIMT---EGLDEMGQDYLDQMASAIPAGRLGSVADIGNAALFFATDEAA 236 Query: 239 GISGEVVHVDGG 250 ++G+ + VDGG Sbjct: 237 YVTGQTLVVDGG 248 >1DOH-A nrPDB Length = 283 Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 68/265 (25%), Positives = 112/265 (42%), Gaps = 29/265 (10%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQL---GSDI- 59 L GK LVTG I +A + R G ++ Y N EE A + GSD Sbjct: 27 LEGKVALVTGAGR--GIGREMAMELGRRGCKVIVNYANSTESA--EEVVAAIKKNGSDAA 82 Query: 60 VLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDI 119 ++ +V I MF E K++ K D + G + +V VT E F I Sbjct: 83 CVKANVGVVEDIVRMFEEAVKIFGKLDIVCSNSGV-----VSFGHVKDVTPEEFDRVFTI 137 Query: 120 SSYSFVAMAKACRSMLNPGSALLTL-SYLGAERAIPNYNVMGLAKASLEANVRYMANAMG 178 ++ +A+ L G L+ + S G +A+P + V +K ++E R MA M Sbjct: 138 NTRGQFFVAREAYKHLEIGGRLILMGSITGQAKAVPKHAVYSGSKGAIETFARCMAIDMA 197 Query: 179 PEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVT-------------PIRRTVTIEDV 225 + + VN ++ G I+T + R+ + + E ++ P+RR D+ Sbjct: 198 DKKITVNVVAPGGIKTDMYHAV--CREYIPNGENLSNEEVDEYAAVQWSPLRRVGLPIDI 255 Query: 226 GNSAAFLCSDLSAGISGEVVHVDGG 250 FL S+ ++G+V+ +DGG Sbjct: 256 ARVVCFLASNDGGWVTGKVIGIDGG 280 >3OSU-A nrPDB Length = 246 Score = 57.8 bits (138), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 72/258 (27%), Positives = 109/258 (42%), Gaps = 31/258 (12%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGR--VEEFAAQLGSDIVLQCD 64 K LVTG AS+ I IA + EG +A Y K K VEE A+ +Q + Sbjct: 5 KSALVTG-ASR-GIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQAN 62 Query: 65 VAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSF 124 VA+ + M E+ + D V++ G + L + +E + F Sbjct: 63 VADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLL----MRMKEQEWDDVIDTNLKGVF 118 Query: 125 VAMAKACRSMLNPGS-ALLTLSYLGAERAIP---NY-----NVMGLAKASLEANVRYMAN 175 + KA ML S A++ LS + P NY V+GL K++ A Sbjct: 119 NCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSA--------AR 170 Query: 176 AMGPEGVRVNAISAGPIRTLAASGIKDFRK--MLAHCEAVTPIRRTVTIEDVGNSAAFLC 233 + G+ VNA++ G I + + D K ML P+ R D+ N+ AFL Sbjct: 171 ELASRGITVNAVAPGFIVSDMTDALSDELKEQMLTQI----PLARFGQDTDIANTVAFLA 226 Query: 234 SDLSAGISGEVVHVDGGF 251 SD + I+G+ +HV+GG Sbjct: 227 SDKAKYITGQTIHVNGGM 244 >5T5Q-A nrPDB Length = 247 Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 60/242 (24%), Positives = 101/242 (41%), Gaps = 22/242 (9%) Query: 20 IAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELG 79 I IA+ H GA L T D + ++ FAA LGS + A+ +S D + Sbjct: 21 IGRAIAELFHASGANLVLT---DLDREGLDAFAASLGSPERIATIKADASSADDAEKTVA 77 Query: 80 KVWPKFDG---FVHSIGFAPGDQL----DGDYVNAVTREGFKIAHDISSYSFVAMAKACR 132 +F G V S G D D+ ++ I+ + K Sbjct: 78 LAMERFGGIDFLVPSAGIYQAKPFAEMSDADWHRTIS---------INLDGVFYLCKRAL 128 Query: 133 SMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPI 192 L S+++TL+ L A R G K ++ + R ++ + P+ RVN +S G I Sbjct: 129 PALKEDSSIVTLASLAAYRGAYVNAHYGATKGAMVSMTRALSRELAPK-TRVNGVSPGII 187 Query: 193 RTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFS 252 T S + + + TP++R ++ + AFLCS ++ ++GE + V+GG Sbjct: 188 ETPMTSEL--LKTRMDETMTQTPLKRLGKPSEIASVIAFLCSPAASFVTGETIQVNGGIY 245 Query: 253 IA 254 +A Sbjct: 246 MA 247 >4JRO-A nrPDB Length = 271 Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 67/261 (25%), Positives = 110/261 (42%), Gaps = 31/261 (11%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQ-NDKLKGRVEEFAAQLGSDI-VL 61 L GK +VTG I IA + +EGA + F Y + + + A+ G ++ + Sbjct: 27 LQGKVAVVTG--GSRGIGRDIAINLAKEGANIFFNYNGSPEAAEETAKLVAEHGVEVEAM 84 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFA--------PGDQLDGDYVNAVTREGF 113 + +VA +D F + + + + D V++ G D+ D D +N + F Sbjct: 85 KANVAIAEDVDAFFKQAIERFGRVDILVNNAGITRDNLLMRMKEDEWD-DVININLKGTF 143 Query: 114 KIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLG-AERAIPNYNVMGLAKASLEANVRY 172 +S M + ++N S + + G A V+GL K + Sbjct: 144 LCTKAVSR---TMMKQRAGKIINMASVVGLIGNAGQANYVASKAGVIGLTKTT------- 193 Query: 173 MANAMGPEGVRVNAISAGPIRTLAASGIKDFRK--MLAHCEAVTPIRRTVTIEDVGNSAA 230 A + P G+ VNA++ G I T + + K MLA P+ T ED+ N+ Sbjct: 194 -ARELAPRGINVNAVAPGFITTDMTDKLDEKTKEAMLAQI----PLGAYGTTEDIANAVL 248 Query: 231 FLCSDLSAGISGEVVHVDGGF 251 FL SD S I+G+ + VDGG Sbjct: 249 FLASDASKYITGQTLSVDGGM 269 >2UVD-A nrPDB Length = 246 Score = 55.5 bits (132), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 72/265 (27%), Positives = 113/265 (42%), Gaps = 37/265 (13%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQ-NDKLKGRVEEFAAQLGSD-IV 60 L GK LVTG AS+ I IA + ++GA + Y N++ V + +LGSD I Sbjct: 1 MLKGKVALVTG-ASR-GIGRAIAIDLAKQGANVVVNYAGNEQKANEVVDEIKKLGSDAIA 58 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQL------DGDYVNAVTREG-F 113 ++ DVA + M + V+ + D V++ G + L + D V +G F Sbjct: 59 VRADVANAEDVTNMVKQTVDVFGQVDILVNNAGVTKDNLLMRMKEEEWDTVINTNLKGVF 118 Query: 114 KIAHDISSY-------SFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASL 166 +S + V +A NPG A +Y+ A+ V+GL K S Sbjct: 119 LCTKAVSRFMMRQRHGRIVNIASVVGVTGNPGQA----NYVAAKAG-----VIGLTKTS- 168 Query: 167 EANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVG 226 A + + VNAI+ G I T + + K A + P + +D+ Sbjct: 169 -------AKELASRNITVNAIAPGFIATDMTDVLDENIK--AEMLKLIPAAQFGEAQDIA 219 Query: 227 NSAAFLCSDLSAGISGEVVHVDGGF 251 N+ F SD S I+G+ ++VDGG Sbjct: 220 NAVTFFASDQSKYITGQTLNVDGGM 244 >3OEC-A nrPDB Length = 317 Score = 55.1 bits (131), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 73/286 (25%), Positives = 115/286 (40%), Gaps = 50/286 (17%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQA----------MHREGAELAFTYQN-DKLKGRVE 49 M L GK +TG A + + A + R+ L + + ++LK V Sbjct: 41 MNRLQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKETVR 100 Query: 50 EFAAQLGSDIVLQCDVAEDAS----IDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYV 105 Q I Q DV + AS +D AE G + D V ++G + G+ V Sbjct: 101 LVEEQGRRIIARQADVRDLASLQAVVDEALAEFGHI----DILVSNVGISN----QGEVV 152 Query: 106 NAVTREGFKIAHDISSYSFVAMAKACRSML-------NPGSALLTLSYLGAERAIPNYNV 158 + ++ DI + + ACR++L GS + S +G R P + Sbjct: 153 SLTDQQW----SDILQTNLIGAWHACRAVLPSMIERGQGGSVIFVSSTVGL-RGAPGQSH 207 Query: 159 MGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVT---- 214 +K ++ + +AN +G +RVN+++ G + T A K + L H E T Sbjct: 208 YAASKHGVQGLMLSLANEVGRHNIRVNSVNPGAVNTEMALNEKLLKMFLPHLENPTREDA 267 Query: 215 ----------PIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGG 250 PI V EDV N+ A+L SD + I G + VDGG Sbjct: 268 AELFSQLTLLPI-PWVEPEDVSNAVAWLASDEARYIHGAAIPVDGG 312 >3R3S-A nrPDB Length = 294 Score = 55.1 bits (131), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 61/256 (23%), Positives = 119/256 (46%), Gaps = 17/256 (6%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTY------QNDKLKGRVEEFAAQL 55 G L ++ LVTG S + A IA A REGA++A Y ++K +EE + Sbjct: 45 GRLKDRKALVTGGDSGIGRAAAIAYA--REGADVAINYLPAEEEDAQQVKALIEECGRKA 102 Query: 56 GSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKI 115 ++L D+++++ ++ + + G + + G Q + +T E F+ Sbjct: 103 ---VLLPGDLSDESFARSLVHKAREAL----GGLDILALVAGKQTAIPEIKDLTSEQFQQ 155 Query: 116 AHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMAN 175 ++ ++ + + +L G++++T S + A + P+ KA++ R +A Sbjct: 156 TFAVNVFALFWITQEAIPLLPKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAK 215 Query: 176 AMGPEGVRVNAISAGPIRT-LAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCS 234 + +G+RVN ++ GPI T L SG + K+ + TP++R ++ +L S Sbjct: 216 QVAEKGIRVNIVAPGPIWTALQISGGQTQDKIPQFGQQ-TPMKRAGQPAELAPVYVYLAS 274 Query: 235 DLSAGISGEVVHVDGG 250 S+ ++ EV V GG Sbjct: 275 QESSYVTAEVHGVCGG 290 >3WOH-A nrPDB Length = 251 Score = 54.7 bits (130), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 80/267 (29%), Positives = 121/267 (45%), Gaps = 37/267 (13%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQND-----KLKGRVEEFAAQLG 56 G LSGK LVTG + L A +A + R+GA +A Y +D + +G +E G Sbjct: 7 GALSGKVALVTGGSRGLGRA--MALRLARDGAAVAIVYVSDDSSAKETQGEIERLG---G 61 Query: 57 SDIVLQCDVAE----DASIDTMFAELGKVWPKFDGFVHSIGFAPGDQL-----DGDYVNA 107 + +CDV++ + + A+LG V D V++ G D L D DY +A Sbjct: 62 TARSYRCDVSDAEQVTRCVKAVTADLGPV----DILVNNAGIIR-DGLAASIKDEDY-DA 115 Query: 108 VTREGFKIAHD-ISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASL 166 V K A I + F + K S++N + ++S + NY AKA L Sbjct: 116 VMNTNLKGAFLFIKACYFGFIRKRSGSIIN----ISSVSGVFGSAGQANY---ASAKAGL 168 Query: 167 EANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVG 226 + +A + VR NA++ G I T + D K L P+RR ++V Sbjct: 169 IGLTKSIAKELAERNVRCNAVAPGLIATDMTQDLVDDSKRLDP----VPMRRFGRPDEVA 224 Query: 227 NSAAFLCSDLSAGISGEVVHVDGGFSI 253 AFL D S+ I+G+VV VDGG ++ Sbjct: 225 GLVAFLAGDESSYITGQVVCVDGGMAM 251 >3U5T-A nrPDB Length = 267 Score = 54.3 bits (129), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 65/261 (24%), Positives = 115/261 (44%), Gaps = 34/261 (13%) Query: 5 SGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN-----DKLKGRVEEFAAQLGSDI 59 + K +VTG + + A IA + +G + Y +++ G++E A G + Sbjct: 26 TNKVAIVTGASRGIGAA--IAARLASDGFTVVINYAGKAAAAEEVAGKIE---AAGGKAL 80 Query: 60 VLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAP-------GDQLDGDYVNAVTREG 112 Q DV++ A++ +FA + + D V++ G P GD + D V AV +G Sbjct: 81 TAQADVSDPAAVRRLFATAEEAFGGVDVLVNNAGIMPLTTIAETGDAVF-DRVIAVNLKG 139 Query: 113 FKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRY 172 +F + +A + L G ++ +S P+Y + AKA +EA Sbjct: 140 ----------TFNTLREAAQR-LRVGGRIINMSTSQVGLLHPSYGIYAAAKAGVEAMTHV 188 Query: 173 MANAMGPEGVRVNAISAGPIRT-LAASGIKD-FRKMLAHCEAVTPIRRTVTIEDVGNSAA 230 ++ + + VNA++ GP T L G D R A + P+ R T +D+ + A Sbjct: 189 LSKELRGRDITVNAVAPGPTATDLFLEGKSDEVRDRFAK---LAPLERLGTPQDIAGAVA 245 Query: 231 FLCSDLSAGISGEVVHVDGGF 251 FL A ++G+V+ +GG Sbjct: 246 FLAGPDGAWVNGQVLRANGGI 266 >3GRP-A nrPDB Length = 266 Score = 53.9 bits (128), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 61/258 (23%), Positives = 115/258 (44%), Gaps = 25/258 (9%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFT-YQNDKLKGRVEEFAAQLGSDI-VL 61 L+G++ LVTG I IA+ H +GA + + DKLK E AA LG D+ V Sbjct: 25 LTGRKALVTGATG--GIGEAIARCFHAQGAIVGLHGTREDKLK----EIAADLGKDVFVF 78 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 ++++ SI + + D V++ G DG +V ++ D+ + Sbjct: 79 SANLSDRKSIKQLAEVAEREMEGIDILVNNAGITR----DGLFVRMQDQD----WDDVLA 130 Query: 122 YSFVAMAKACRSMLNP------GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMAN 175 + A + R +++ G + S +G P AKA L + +A Sbjct: 131 VNLTAASTLTRELIHSMMRRRYGRIINITSIVGVV-GNPGQTNYCAAKAGLIGFSKALAQ 189 Query: 176 AMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSD 235 + + VN I+ G I++ + + +K A+ P++R E++ + +L SD Sbjct: 190 EIASRNITVNCIAPGFIKSAMTDKLNEKQK--EAIMAMIPMKRMGIGEEIAFATVYLASD 247 Query: 236 LSAGISGEVVHVDGGFSI 253 +A ++G+ +H++GG ++ Sbjct: 248 EAAYLTGQTLHINGGMAM 265 >2ZAT-A nrPDB Length = 260 Score = 53.9 bits (128), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 42/151 (27%), Positives = 73/151 (48%), Gaps = 3/151 (1%) Query: 102 GDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNP--GSALLTLSYLGAERAIPNYNVM 159 G+ ++A KI H ++ + V M KA + G ++L +S +GA PN Sbjct: 106 GNIIDATEEVWDKILH-VNVKATVLMTKAVVPEMEKRGGGSVLIVSSVGAYHPFPNLGPY 164 Query: 160 GLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRT 219 ++K +L + +A + P +RVN ++ G I+T + + + + + IRR Sbjct: 165 NVSKTALLGLTKNLAVELAPRNIRVNCLAPGLIKTNFSQVLWMDKARKEYMKESLRIRRL 224 Query: 220 VTIEDVGNSAAFLCSDLSAGISGEVVHVDGG 250 ED +FLCS+ ++ I+GE V V GG Sbjct: 225 GNPEDCAGIVSFLCSEDASYITGETVVVGGG 255 >3UF0-A nrPDB Length = 273 Score = 53.9 bits (128), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 68/256 (26%), Positives = 115/256 (44%), Gaps = 22/256 (8%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 L+G+ +VTG S I IA R GA + + D +K +E A GS + Sbjct: 29 LAGRTAVVTGAGS--GIGRAIAHGYARAGAHVLAWGRTDGVKEVADEIADGGGSAEAVVA 86 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGF---APGDQLD-GDYVNAVTREGFKIAHD- 118 D+A+ + EL + D V++ G AP +++ G + RE + D Sbjct: 87 DLADLEGAANVAEELAAT-RRVDVLVNNAGIIARAPAEEVSLGRW-----REVLTVNLDA 140 Query: 119 --ISSYSFVAMAKACRSMLNPGSA-LLTLSYLGAERAIPNYNVMGLAKASLEANVRYMAN 175 + S SF +ML GS ++T++ + + + N +K ++ R +A+ Sbjct: 141 AWVLSRSF------GTAMLAHGSGRIVTIASMLSFQGGRNVAAYAASKHAVVGLTRALAS 194 Query: 176 AMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSD 235 GV VNA++ G + T + ++ + A A P R T ED+ A FL SD Sbjct: 195 EWAGRGVGVNALAPGYVVTANTAALRADDERAAEITARIPAGRWATPEDMVGPAVFLASD 254 Query: 236 LSAGISGEVVHVDGGF 251 ++ + G+V+ VDGG+ Sbjct: 255 AASYVHGQVLAVDGGW 270 >1AE1-A nrPDB Length = 273 Score = 53.9 bits (128), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 64/262 (24%), Positives = 119/262 (45%), Gaps = 25/262 (9%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQ- 62 L G LVTG SK I Y I + + GA + +N+K E + G ++ Sbjct: 19 LKGTTALVTG-GSK-GIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREKGLNVEGSV 76 Query: 63 CDVAEDASIDTMFAELGKVWPKFDG----FVHSIGFA----PGDQLDGDYVNAVTREGFK 114 CD+ D + + V FDG V++ G D + DY N + F+ Sbjct: 77 CDLLSRTERDKLMQTVAHV---FDGKLNILVNNAGVVIHKEAKDFTEKDY-NIIMGTNFE 132 Query: 115 IAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMA 174 A+ +S ++ + KA ++ ++ LS + A+P+ ++ +K ++ + +A Sbjct: 133 AAYHLSQIAY-PLLKASQN-----GNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLA 186 Query: 175 NAMGPEGVRVNAISAGPIRT-LAASGIKDF---RKMLAHCEAVTPIRRTVTIEDVGNSAA 230 + +RVN+++ G I T L + IK ++ + + TP+ R ++V A Sbjct: 187 CEWAKDNIRVNSVAPGVILTPLVETAIKKNPHQKEEIDNFIVKTPMGRAGKPQEVSALIA 246 Query: 231 FLCSDLSAGISGEVVHVDGGFS 252 FLC ++ I+G+++ DGGF+ Sbjct: 247 FLCFPAASYITGQIIWADGGFT 268 >4AVY-A nrPDB Length = 242 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 68/255 (26%), Positives = 111/255 (43%), Gaps = 33/255 (12%) Query: 5 SGKRILVTGVASKLSIAYGIAQAMHREGAEL-AFTYQNDKLKG------RVEEFAAQLGS 57 +G+++LVTG +S + A IA GAE+ A D + R EE Sbjct: 10 AGQQVLVTGGSSGIGAA--IAMQFAELGAEVVALGLDADGVHAPRHPRIRREEL------ 61 Query: 58 DIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPG-DQLDGDYVNAVTREGFKIA 116 D+ + + +F L P+ D V++ G + ++ D V R A Sbjct: 62 ------DITDSQRLQRLFEAL----PRLDVLVNNAGISRDREEYDLATFERVLRLNLSAA 111 Query: 117 HDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANA 176 S + +A+ S+LN S T A+R P Y+ +K ++ R +A Sbjct: 112 MLASQLARPLLAQRGGSILNIASMYSTFG--SADR--PAYSA---SKGAIVQLTRSLACE 164 Query: 177 MGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDL 236 E +RVNAI+ G I T +G+K + TP+ R +V ++AAFLC Sbjct: 165 YAAERIRVNAIAPGWIDTPLGAGLKADVEATRRIMQRTPLARWGEAPEVASAAAFLCGPG 224 Query: 237 SAGISGEVVHVDGGF 251 ++ ++G V+ VDGG+ Sbjct: 225 ASFVTGAVLAVDGGY 239 >3O4R-A nrPDB Length = 261 Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 63/255 (24%), Positives = 114/255 (44%), Gaps = 19/255 (7%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQL-GSDIVLQ 62 L+ K LVT AS I + IA+ + ++GA + + + + V++ A L G + + Sbjct: 13 LANKVALVT--ASTDGIGFAIARRLAQDGAHVVVSSRKQQ---NVDQAVATLQGEGLSVT 67 Query: 63 ---CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAP--GDQLDGDYVNAVTREGFKIAH 117 C V + + + A K+ D V + P G +D VT E + Sbjct: 68 GTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMD------VTEEVWDKTL 121 Query: 118 DISSYSFVAMAKACRSMLNP--GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMAN 175 DI+ + M KA + G +++ +S + A P ++ ++K +L + +A Sbjct: 122 DINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAI 181 Query: 176 AMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSD 235 + P +RVN ++ G I+T + + ++ + IRR ED +FLCS+ Sbjct: 182 ELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSE 241 Query: 236 LSAGISGEVVHVDGG 250 ++ I+GE V V GG Sbjct: 242 DASYITGETVVVGGG 256 >3UCF-A nrPDB Length = 223 Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 50/192 (26%), Positives = 89/192 (46%), Gaps = 18/192 (9%) Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIG-FAP-GDQLDGDYVNAVTREGFKIAHDIS 120 D++++ S+ F +G FD + + G +AP G +D + A K A D Sbjct: 42 LDISDEKSVYHYFETIGA----FDHLIVTAGSYAPAGKVVDVEVTQA------KYAFDTK 91 Query: 121 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 + V AK L G ++ S + + + + N V A++EA + +A + P Sbjct: 92 FWGAVLAAKHGARYLKQGGSITLTSGMLSRKVVANTYVKAAINAAIEATTKVLAKELAP- 150 Query: 181 GVRVNAISAGPIRTLAASGIK--DFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSA 238 +RVNAIS G +T A G+ D M ++ P+ + D+ + A+L + ++ Sbjct: 151 -IRVNAISPGLTKTEAYKGMNADDRDAMYQRTQSHLPVGKVGEASDI--AMAYLFAIQNS 207 Query: 239 GISGEVVHVDGG 250 ++G V+ VDGG Sbjct: 208 YMTGTVIDVDGG 219 >1Q7C-A nrPDB Length = 244 Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 63/250 (25%), Positives = 114/250 (45%), Gaps = 17/250 (6%) Query: 6 GKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDV 65 GK LVTG AS+ I IA+ + GA++ T ++ + ++ G ++L +V Sbjct: 5 GKIALVTG-ASR-GIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLML--NV 60 Query: 66 AEDASIDTMFAELGKVWPKFDGFVHSIGFAPGD---QLDGDYVNAVTREGFKIAHDISSY 122 + ASI+++ ++ + + D V++ G + ++ + N + +S Sbjct: 61 TDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFRLSKA 120 Query: 123 SFVAMAKACRS-MLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 AM K ++ GS + T+ G N+ AKA L + +A + G Sbjct: 121 VMRAMMKKRHGRIITIGSVVGTMGNGGQ----ANF---AAAKAGLIGFSKSLAREVASRG 173 Query: 182 VRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGIS 241 + VN ++ G I T + D ++ A A P R +++ N+ AFL SD +A I+ Sbjct: 174 ITVNVVAPGFIETDMTRALSDDQR--AGILAQVPAGRLGGAQEIANAVAFLASDEAAYIT 231 Query: 242 GEVVHVDGGF 251 GE +HV+GG Sbjct: 232 GETLHVNGGM 241 >5CDY-A nrPDB Length = 244 Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 64/250 (25%), Positives = 113/250 (45%), Gaps = 17/250 (6%) Query: 6 GKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDV 65 GK LVTG AS+ I IA+ + GA + T ++K + + + G ++L +V Sbjct: 5 GKIALVTG-ASR-GIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGKGLML--NV 60 Query: 66 AEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQL----DGDYVNAVTREGFKIAHDISS 121 + SIDT+ A + + + D V++ G + L D ++ + + + + Sbjct: 61 VDPTSIDTVLATIRAEFGEVDILVNNAGITRDNLLMRMKDDEWQDIIDTNLTSVFRLSKA 120 Query: 122 YSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 M K ++ GS + T+ G NY AKA + + +A + G Sbjct: 121 VMRAMMKKRFGRIITIGSVVGTMGNAGQ----VNY---AAAKAGVIGFSKSLAREVASRG 173 Query: 182 VRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGIS 241 + VN ++ G I T + D ++ A A P R +++ ++ AFL SD ++ IS Sbjct: 174 ITVNVVAPGFIETDMTRTLTDDQR--AGILAQVPANRLGDAKEIASAVAFLASDEASYIS 231 Query: 242 GEVVHVDGGF 251 GE +HV+GG Sbjct: 232 GETLHVNGGM 241 >2EW8-A nrPDB Length = 249 Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 69/253 (27%), Positives = 118/253 (46%), Gaps = 18/253 (7%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQ-LGSDIV-L 61 L K ++TG A+ I IA+ EGA++A D + E A + LG ++ + Sbjct: 5 LKDKLAVITGGAN--GIGRAIAERFAVEGADIAIA---DLVPAPEAEAAIRNLGRRVLTV 59 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 +CDV++ ++ ++ + + D V++ G P D +T E +K +I+ Sbjct: 60 KCDVSQPGDVEAFGKQVISTFGRCDILVNNAGIYPLIPFD-----ELTFEQWKKTFEINV 114 Query: 122 YSFVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 S MAKA + N ++ L+ I Y KA+ R +A+ +G Sbjct: 115 DSGFLMAKAFVPGMKRNGWGRIINLTSTTYWLKIEAYTHYISTKAANIGFTRALASDLGK 174 Query: 180 EGVRVNAISAGPIRTLA--ASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLS 237 +G+ VNAI+ +RT AS + +L + P R V + D+ +AAFL SD + Sbjct: 175 DGITVNAIAPSLVRTATTEASALSAMFDVLPNMLQAIP-RLQVPL-DLTGAAAFLASDDA 232 Query: 238 AGISGEVVHVDGG 250 + I+G+ + VDGG Sbjct: 233 SFITGQTLAVDGG 245 >1HXH-A nrPDB Length = 253 Score = 52.0 bits (123), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 67/253 (26%), Positives = 116/253 (45%), Gaps = 19/253 (7%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGS-DIVLQ 62 L GK LVTG AS + + + + + EGA++AF+ N+ ++ AA+LG + ++ Sbjct: 4 LQGKVALVTGGASGVGLE--VVKLLLGEGAKVAFSDINEAAG---QQLAAELGERSMFVR 58 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIG-FAPGDQLDGDYVNAVTREGFKIAHDISS 121 DV+ +A + A + + + V++ G PGD G E F I++ Sbjct: 59 HDVSSEADWTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRL------EDFSRLLKINT 112 Query: 122 YS-FVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 S F+ + +M G +++ ++ + + I Y +KA++ A R A + + Sbjct: 113 ESVFIGCQQGIAAMKETGGSIINMASVSSWLPIEQYAGYSASKAAVSALTRAAALSCRKQ 172 Query: 181 G--VRVNAISAGPIRT--LAASGIKDFRK-MLAHCEAVTPIRRTVTIEDVGNSAAFLCSD 235 G +RVN+I I T + AS K K M+ H + R E + FL SD Sbjct: 173 GYAIRVNSIHPDGIYTPMMQASLPKGVSKEMVLHDPKLNRAGRAYMPERIAQLVLFLASD 232 Query: 236 LSAGISGEVVHVD 248 S+ +SG +H D Sbjct: 233 ESSVMSGSELHAD 245 >4FC7-A nrPDB Length = 277 Score = 52.0 bits (123), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 30/97 (30%), Positives = 56/97 (57%), Gaps = 11/97 (11%) Query: 160 GLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKM------LAHCEAV 213 G AKA+++A R++A GP+ +RVN+++ GPI SG + R++ L+ Sbjct: 178 GSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPI-----SGTEGLRRLGGPQASLSTKVTA 232 Query: 214 TPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGG 250 +P++R ++ +S +L S L++ ++G V+ DGG Sbjct: 233 SPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGG 269 >4GKB-A nrPDB Length = 258 Score = 52.0 bits (123), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 52/198 (26%), Positives = 88/198 (44%), Gaps = 12/198 (6%) Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 L ++ +DA A+ + + DG V++ G G LD R+ F + + + Sbjct: 60 LPVELQDDAQCRDAVAQTIATFGRLDGLVNNAGVNDGIGLDAG------RDAFVASLERN 113 Query: 121 SYSFVAMAKACRSMLNPGS-ALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 + AMA C L A++ +S A N + +K + A R A A+ Sbjct: 114 LIHYYAMAHYCVPHLKATRGAIVNISSKTAVTGQGNTSGYCASKGAQLALTREWAVALRE 173 Query: 180 EGVRVNAISAG----PIRTLAASGIKDFRKMLAHCEAVTPI-RRTVTIEDVGNSAAFLCS 234 GVRVNA+ P+ + +D LA A P+ RR T +++ ++A FL S Sbjct: 174 HGVRVNAVIPAEVMTPLYRNWIATFEDPEAKLAEIAAKVPLGRRFTTPDEIADTAVFLLS 233 Query: 235 DLSAGISGEVVHVDGGFS 252 ++ +GE + VDGG++ Sbjct: 234 PRASHTTGEWLFVDGGYT 251 >2NM0-A nrPDB Length = 253 Score = 50.8 bits (120), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 59/250 (23%), Positives = 112/250 (44%), Gaps = 23/250 (9%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVA 66 + +LVTG I IA+A G ++A TY++ + E F A ++CD+ Sbjct: 22 RSVLVTG--GNRGIGLAIARAFADAGDKVAITYRSGEPP---EGFLA-------VKCDIT 69 Query: 67 EDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGF-KIAHDISSYSFV 125 + ++ + E+ + + + + G DQL + ++ E F + + +F Sbjct: 70 DTEQVEQAYKEIEETHGPVEVLIANAGVTK-DQL----LMRMSEEDFTSVVETNLTGTFR 124 Query: 126 AMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVR 183 + +A R+ML G +L S +G + N +KA L R +A +G + Sbjct: 125 VVKRANRAMLRAKKGRVVLISSVVGLLGSAGQAN-YAASKAGLVGFARSLARELGSRNIT 183 Query: 184 VNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGE 243 N ++ G + T + D ++ A+ + P+ R E++ + FL SD ++ I+G Sbjct: 184 FNVVAPGFVDTDMTKVLTDEQR--ANIVSQVPLGRYARPEEIAATVRFLASDDASYITGA 241 Query: 244 VVHVDGGFSI 253 V+ VDGG + Sbjct: 242 VIPVDGGLGM 251 >5OVJ-A nrPDB Length = 256 Score = 50.1 bits (118), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 61/257 (23%), Positives = 113/257 (43%), Gaps = 30/257 (11%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN----DKLKGRVEEFAAQLGSD 58 F+S + +LVTG I IA+ + +G ++A T++ D L G Sbjct: 22 FVS-RSVLVTG--GNRGIGLAIARRLAADGHKVAVTHRGSGAPDDLFG------------ 66 Query: 59 IVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFK-IAH 117 +QCDV + A++D F E+ + + V + G + ++ +T E F+ + + Sbjct: 67 --VQCDVTDSAAVDRAFKEVEEHQGPVEVLVANAGIS-----KDAFLMRMTEERFEEVIN 119 Query: 118 DISSYSFVAMAKACRSMLNPG-SALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANA 176 + +F +A R+M ++ + + I N AKA L R ++ Sbjct: 120 TNLTGAFRCAQRASRTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRE 179 Query: 177 MGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDL 236 + GV N ++ G I T + + ++ A P +R T E+V + +FL S+ Sbjct: 180 LAKAGVTANVVAPGYIDTEMTRALDE--RIQAGALDFIPAKRVGTAEEVAGAVSFLASED 237 Query: 237 SAGISGEVVHVDGGFSI 253 ++ I+G V+ VDGG + Sbjct: 238 ASYIAGAVIPVDGGMGM 254 >5OVL-A nrPDB Length = 300 Score = 50.1 bits (118), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 61/257 (23%), Positives = 113/257 (43%), Gaps = 30/257 (11%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN----DKLKGRVEEFAAQLGSD 58 F+S + +LVTG I IA+ + +G ++A T++ D L G Sbjct: 66 FVS-RSVLVTG--GNRGIGLAIARRLAADGHKVAVTHRGSGAPDDLFG------------ 110 Query: 59 IVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFK-IAH 117 +QCDV + A++D F E+ + + V + G + ++ +T E F+ + + Sbjct: 111 --VQCDVTDSAAVDRAFKEVEEHQGPVEVLVANAGIS-----KDAFLMRMTEERFEEVIN 163 Query: 118 DISSYSFVAMAKACRSMLNPG-SALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANA 176 + +F +A R+M ++ + + I N AKA L R ++ Sbjct: 164 TNLTGAFRCAQRASRTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRE 223 Query: 177 MGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDL 236 + GV N ++ G I T + + ++ A P +R T E+V + +FL S+ Sbjct: 224 LAKAGVTANVVAPGYIDTEMTRALDE--RIQAGALDFIPAKRVGTAEEVAGAVSFLASED 281 Query: 237 SAGISGEVVHVDGGFSI 253 ++ I+G V+ VDGG + Sbjct: 282 ASYIAGAVIPVDGGMGM 298 >6NRP-A nrPDB Length = 263 Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 63/258 (24%), Positives = 112/258 (43%), Gaps = 33/258 (12%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGR--VEEFAAQLGSDIVLQCD 64 +RILVTG S I IA + + G ++ ++ + + V+E A + L D Sbjct: 25 RRILVTG--SSRGIGKAIALQLAKAGFDVTVHARSRQAEAEQVVQEIQALGQNSHYLMFD 82 Query: 65 VAEDASIDTMFAELGKVWPKFDGFVHSIGF-------APGDQLDGDYVNAVTREGFKIAH 117 V E ++ + + + F G V + G A DQ D D V + + +GF Sbjct: 83 VNERQTVQQILEQDVEQHGGFYGVVLNAGLTHDGAFPALTDQ-DWDEVISTSLDGF---- 137 Query: 118 DISSYSFVAMAKACRSMLNPGSALLTLSYLGA---ERAIPNYNVMGLAKASLEANVRYMA 174 Y+ + L G ++TLS + R NY+ AKA L + +A Sbjct: 138 ----YNVLKPLIMPMIHLRKGGRIVTLSSVSGIMGNRGQVNYSA---AKAGLIGATKALA 190 Query: 175 NAMGPEGVRVNAISAGPIRT-LAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLC 233 + + VN ++ G I T + +K+ H + P++R +++V + FLC Sbjct: 191 LELAKRKITVNCVAPGLIETEMVTDEVKE------HALKMIPLQRMGQVDEVASVVKFLC 244 Query: 234 SDLSAGISGEVVHVDGGF 251 SD ++ ++ +V+ V+GG Sbjct: 245 SDEASYVTRQVISVNGGL 262 >4M8S-A nrPDB Length = 248 Score = 48.5 bits (114), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 64/256 (25%), Positives = 112/256 (43%), Gaps = 24/256 (9%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 LSGK LVTG + I IA + GA++ T ++ + E AQ G + + Sbjct: 6 LSGKIALVTGASR--GIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGGEGRV-L 62 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 + AE +++ + A++ K + K D V++ G N + R + DI + Sbjct: 63 NSAEPETVENLIADIEKTFGKLDILVNNAGITRD--------NLLMRMKEEEWDDIMQVN 114 Query: 124 FVAMAKACRSMLN------PGSALLTLSYLG--AERAIPNYNVMGLAKASLEANVRYMAN 175 ++ +A +++L G + S +G NY AKA L + MA Sbjct: 115 LKSVFRASKAVLRGMMKQRAGRIINITSVVGVMGNAGQTNY---AAAKAGLIGFSKSMAR 171 Query: 176 AMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSD 235 +G G+ VN ++ G I T + + + A T + R +D+ ++ FL SD Sbjct: 172 EVGSRGITVNCVAPGFIDTDMTRALPEETRQ--TFTAQTALGRFGDAQDIADAVLFLASD 229 Query: 236 LSAGISGEVVHVDGGF 251 + I+G+ +HV+GG Sbjct: 230 QAKYITGQTLHVNGGM 245 >2HQ1-A nrPDB Length = 247 Score = 48.5 bits (114), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 63/256 (24%), Positives = 112/256 (43%), Gaps = 21/256 (8%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAF--TYQNDKLKGRVEEFAAQLGSDIVL 61 L GK +VTG + L A IA + GA + + + L EEF A + +V Sbjct: 3 LKGKTAIVTGSSRGLGKA--IAWKLGNMGANIVLNGSPASTSLDATAEEFKAAGINVVVA 60 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQL-----DGDYVNAVTREGFKIA 116 + DV ++ M + + D V++ G D L + D+ + V K A Sbjct: 61 KGDVKNPEDVENMVKTAMDAFGRIDILVNNAGITR-DTLMLKMSEKDW-DDVLNTNLKSA 118 Query: 117 HDIS-SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMAN 175 + + + S + + + ++N + +++ + NY +KA L + +A Sbjct: 119 YLCTKAVSKIMLKQKSGKIIN----ITSIAGIIGNAGQANY---AASKAGLIGFTKSIAK 171 Query: 176 AMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSD 235 +G+ NA++ G I+T + D K + P++R T E+V N FL SD Sbjct: 172 EFAAKGIYCNAVAPGIIKTDMTDVLPDKVKEMYLNN--IPLKRFGTPEEVANVVGFLASD 229 Query: 236 LSAGISGEVVHVDGGF 251 S I+G+V+++DGG Sbjct: 230 DSNYITGQVINIDGGL 245 >3V2G-A nrPDB Length = 271 Score = 47.4 bits (111), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 65/259 (25%), Positives = 105/259 (40%), Gaps = 31/259 (11%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN--DKLKGRVEEFAAQLGSDIVL 61 L+GK VTG I IA+ + EGA +A TY N ++ + V E G + + Sbjct: 29 LAGKTAFVTG--GSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQAGGRAVAI 86 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGF---APGDQL---DGDYVNAVTREGFKI 115 + D + +I+ E + D V+S G AP ++ D D V AV F+ Sbjct: 87 RADNRDAEAIEQAIRETVEALGGLDILVNSAGIWHSAPLEETTVADFDEVMAVN---FR- 142 Query: 116 AHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMAN 175 FVA+ A R + + G + S L P ++ +KA+L + +A Sbjct: 143 ------APFVAIRSASRHLGDGGRIITIGSNLAELVPWPGISLYSASKAALAGLTKGLAR 196 Query: 176 AMGPEGVRVNAISAGPIRTLAASGIKDF----RKMLAHCEAVTPIRRTVTIEDVGNSAAF 231 +GP G+ VN + G T D R+ +A P +D+ A+ Sbjct: 197 DLGPRGITVNIVHPGSTDTDMNPADGDHAEAQRERIATGSYGEP-------QDIAGLVAW 249 Query: 232 LCSDLSAGISGEVVHVDGG 250 L ++G + +DGG Sbjct: 250 LAGPQGKFVTGASLTIDGG 268 >4DMM-A nrPDB Length = 269 Score = 47.0 bits (110), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 51/210 (24%), Positives = 88/210 (41%), Gaps = 41/210 (19%) Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQL----DGDYVNAV--------- 108 + DV++++ ++ +FA + + W + D V++ G L D+ + + Sbjct: 84 KADVSQESEVEALFAAVIERWGRLDVLVNNAGITRDTLLLRMKRDDWQSVLDLNLGGVFL 143 Query: 109 -TREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLE 167 +R KI S + +A M NPG A NY+ AKA + Sbjct: 144 CSRAAAKIMLKQRSGRIINIASVVGEMGNPGQA--------------NYSA---AKAGVI 186 Query: 168 ANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLA--HCEAVTPIRRTVTIEDV 225 + +A + G+ VNA++ G I T D LA V P+ R +V Sbjct: 187 GLTKTVAKELASRGITVNAVAPGFIAT-------DMTSELAAEKLLEVIPLGRYGEAAEV 239 Query: 226 GNSAAFLCSDLSAG-ISGEVVHVDGGFSIA 254 FL +D +A I+G+V+++DGG +A Sbjct: 240 AGVVRFLAADPAAAYITGQVINIDGGLVMA 269 >1K2W-A nrPDB Length = 256 Score = 47.0 bits (110), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 67/261 (25%), Positives = 108/261 (41%), Gaps = 25/261 (9%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLG-SDIVLQ 62 L GK L+TG A + A+ A+A REGA +A N + AA++G + + Sbjct: 3 LDGKTALITGSARGIGRAF--AEAYVREGARVAIADINLEA---ARATAAEIGPAACAIA 57 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFK--IAHDIS 120 DV + ASID AEL W D V++ D + +TRE + A ++S Sbjct: 58 LDVTDQASIDRCVAELLDRWGSIDILVNNAAL-----FDLAPIVEITRESYDRLFAINVS 112 Query: 121 SYSFVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMG 178 F+ M R+M+ G ++ ++ R V KA++ + + + Sbjct: 113 GTLFM-MQAVARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNLI 171 Query: 179 PEGVRVNAISAGPIRTLAASGIK----DFRKM-----LAHCEAVTPIRRTVTIEDVGNSA 229 G+ VNAI+ G + G+ D+ + A P R ED+ A Sbjct: 172 RHGINVNAIAPGVVDGEHWDGVDAKFADYENLPRGEKKRQVGAAVPFGRMGRAEDLTGMA 231 Query: 230 AFLCSDLSAGISGEVVHVDGG 250 FL + + I + +VDGG Sbjct: 232 IFLATPEADYIVAQTYNVDGG 252 >4IIN-A nrPDB Length = 271 Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 63/255 (24%), Positives = 113/255 (44%), Gaps = 19/255 (7%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN-----DKLKGRVEEFAAQLGSD 58 +GK +L+TG ASK I IA+ + G ++ Y++ D LK +EE + Sbjct: 27 FTGKNVLITG-ASK-GIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAA-- 82 Query: 59 IVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHD 118 V++ D A ++ F E + + DG + + G D + T + + + Sbjct: 83 -VIKFDAASESD----FIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDN 137 Query: 119 ISSYSFVAMAKACRSMLNP--GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANA 176 + +F+ +A + M GS + S +G ER +K + A + A Sbjct: 138 NLTSAFIGCREALKVMSKSRFGSVVNVASIIG-ERGNMGQTNYSASKGGMIAMSKSFAYE 196 Query: 177 MGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDL 236 +R N+++ G I T + +KD ++ A P+ R + ++V + AFL SD Sbjct: 197 GALRNIRFNSVTPGFIETDMNANLKD--ELKADYVKNIPLNRLGSAKEVAEAVAFLLSDH 254 Query: 237 SAGISGEVVHVDGGF 251 S+ I+GE + V+GG Sbjct: 255 SSYITGETLKVNGGL 269 >4HP8-A nrPDB Length = 247 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 68/259 (26%), Positives = 114/259 (44%), Gaps = 32/259 (12%) Query: 4 LSGKRILVTGVASKL--SIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVL 61 L G++ LVTG + L +IA G+A A GAE+ + + ++ A G+ L Sbjct: 7 LEGRKALVTGANTGLGQAIAVGLAAA----GAEVVCAARRAPDE-TLDIIAKDGGNASAL 61 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGF------APGDQLDGDYVNAVTREGFKI 115 D A+ + F + G FD V++ G +LD D V V + Sbjct: 62 LIDFADPLAAKDSFTDAG-----FDILVNNAGIIRRADSVEFSELDWDEVMDVNLKALFF 116 Query: 116 AHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMAN 175 + +A ++ + ++N S LS+ G R +P+Y AK + + +AN Sbjct: 117 TTQAFAKELLAKGRSGK-VVNIAS---LLSFQGGIR-VPSYTA---AKHGVAGLTKLLAN 168 Query: 176 AMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAV---TPIRRTVTIEDVGNSAAFL 232 +G+ VNAI+ G I T + + R A +A+ P R ED+ +A FL Sbjct: 169 EWAAKGINVNAIAPGYIET---NNTEALRADAARNKAILERIPAGRWGHSEDIAGAAVFL 225 Query: 233 CSDLSAGISGEVVHVDGGF 251 S + + G +++VDGG+ Sbjct: 226 SSAAADYVHGAILNVDGGW 244 >5YSS-A nrPDB Length = 256 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 72/261 (27%), Positives = 107/261 (40%), Gaps = 23/261 (8%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTY--QNDKLKGRVEEFAAQLGSDIVL 61 L+GK LVTG S I GIAQ + + GA L D K V ++ G Sbjct: 3 LTGKTALVTGSTS--GIGLGIAQVLAQAGATLILNGFGDVDAAKDAVAQYGKTPGYH--- 57 Query: 62 QCDVAEDASIDTMF----AELGKVWPKFDGFVHSIGF---APGDQLDGDYVNAVTREGFK 114 D++++A I M +E G V D +++ G +P + D NA+ Sbjct: 58 GADLSDEAQIADMMRYAESEFGGV----DILINNAGIQHVSPIETFPVDKWNAIIAINLS 113 Query: 115 IAHDISSYSFVAM-AKACRSMLNPGSAL-LTLSYLGAERAIPNYNVMGLAKA-SLE-ANV 170 + + M A+ ++N S L S + + V+GL K +LE A Sbjct: 114 SVFHTTRLALPGMRARNWGRIINIASVHGLVASKEKSAYVAAKHGVVGLTKTIALETAQT 173 Query: 171 RYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAA 230 NA+ P G + + I A G + A P R VT E +GN A Sbjct: 174 EITCNALCP-GWVLTPLVQQQIDKRIAEGAEPEAARDALLAEKQPSREFVTPEQLGNLAL 232 Query: 231 FLCSDLSAGISGEVVHVDGGF 251 FLCSD +A + G ++DGG+ Sbjct: 233 FLCSDGAAQVRGVAWNMDGGW 253 >3FTP-A nrPDB Length = 270 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 56/233 (24%), Positives = 95/233 (40%), Gaps = 26/233 (11%) Query: 24 IAQAMHREGAE-LAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVW 82 I A GAE + ++ L+GR G+ + + A DA +++ E G Sbjct: 56 IGTATTEAGAEGIGAAFKQAGLEGR--------GAVLNVNDATAVDALVESTLKEFGA-- 105 Query: 83 PKFDGFVHSIGFAPGDQL----DGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPG 138 + V++ G DQL D +AV K +S M KA G Sbjct: 106 --LNVLVNNAGITQ-DQLAMRMKDDEWDAVIDTNLKAVFRLSRAVLRPMMKA------RG 156 Query: 139 SALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAAS 198 ++ ++ + P AKA + R +A +G G+ VN ++ G I T Sbjct: 157 GRIVNITSVVGSAGNPGQVNYAAAKAGVAGMTRALAREIGSRGITVNCVAPGFIDTDMTK 216 Query: 199 GIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGF 251 G+ ++ + P+ R + ED+ ++ AFL S + I+G +HV+GG Sbjct: 217 GLPQEQQTALKTQ--IPLGRLGSPEDIAHAVAFLASPQAGYITGTTLHVNGGM 267 >3EMK-A nrPDB Length = 246 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 58/260 (22%), Positives = 117/260 (45%), Gaps = 29/260 (11%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFT-YQNDKLKGRVEEFAAQLGSDI-VL 61 L+G++ LVTG L A IA+A+H +GA + + +KLK E AA+LG I V Sbjct: 5 LTGRKALVTGATGGLGEA--IARALHAQGAIVGLHGTREEKLK----ELAAELGERIFVF 58 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 ++++ ++ + + + D V++ G DG +V R + + + Sbjct: 59 PANLSDREAVKALGQKAEEEMGGVDILVNNAGITR----DGLFV----RMSDEDWDAVLT 110 Query: 122 YSFVAMAKACRSMLNP-----GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANA 176 + ++ R + +P ++ ++ + P +KA L + +A Sbjct: 111 VNLTSVFNLTRELTHPMMRRRNGRIINITSIVGVTGNPGQANYCASKAGLIGFSKSLAQE 170 Query: 177 MGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAV---TPIRRTVTIEDVGNSAAFLC 233 + V VN I+ G I + + + +K +A+ P++R D+ + +L Sbjct: 171 IASRNVTVNCIAPGFIESAMTGKLNEKQK-----DAIMGNIPMKRMGVGADIAAAVVYLA 225 Query: 234 SDLSAGISGEVVHVDGGFSI 253 SD +A ++G+ +HV+GG ++ Sbjct: 226 SDEAAYVTGQTLHVNGGMAM 245 >2QHX-A nrPDB Length = 328 Score = 45.1 bits (105), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 71/284 (25%), Positives = 112/284 (39%), Gaps = 48/284 (16%) Query: 10 LVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEF---AAQLGSDIVLQCDVA 66 LVTG A +L IA+ +H EG + Y + A + S I +Q D++ Sbjct: 50 LVTGAAKRL--GRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLS 107 Query: 67 EDASID----------TMFAELGKV-------WPKFDGFVHSIG-FAPGDQL----DGDY 104 A+ T+F ++ W + D V++ F P L DG Sbjct: 108 NVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHE 167 Query: 105 VNAVTREGFKIA-------HDISSYSFVAMAKACRSMLNP----GSALLTLSYLGAERAI 153 RE + A + I+ Y F+ A A R P G+ ++ + A Sbjct: 168 PCVGDREAMETATADLFGSNAIAPY-FLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQ 226 Query: 154 P--NYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKML--AH 209 P Y + +AK +LE R A + P +RVN + G + L + D + H Sbjct: 227 PLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPG-LSVL----VDDMPPAVWEGH 281 Query: 210 CEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSI 253 V +R + +V + FLCS + I+G V VDGG+S+ Sbjct: 282 RSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSL 325 >2BFA-A nrPDB Length = 288 Score = 45.1 bits (105), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 71/284 (25%), Positives = 112/284 (39%), Gaps = 48/284 (16%) Query: 10 LVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEF---AAQLGSDIVLQCDVA 66 LVTG A +L IA+ +H EG + Y + A + S I +Q D++ Sbjct: 10 LVTGAAKRL--GRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLS 67 Query: 67 EDASID----------TMFAELGKV-------WPKFDGFVHSIG-FAPGDQL----DGDY 104 A+ T+F ++ W + D V++ F P L DG Sbjct: 68 NVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHE 127 Query: 105 VNAVTREGFKIA-------HDISSYSFVAMAKACRSMLNP----GSALLTLSYLGAERAI 153 RE + A + I+ Y F+ A A R P G+ ++ + A Sbjct: 128 PCVGDREAMETATADLFGSNAIAPY-FLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQ 186 Query: 154 P--NYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKML--AH 209 P Y + +AK +LE R A + P +RVN + G + L + D + H Sbjct: 187 PLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPG-LSVL----VDDMPPAVWEGH 241 Query: 210 CEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSI 253 V +R + +V + FLCS + I+G V VDGG+S+ Sbjct: 242 RSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSL 285 >1P33-A nrPDB Length = 289 Score = 45.1 bits (105), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 75/295 (25%), Positives = 120/295 (40%), Gaps = 70/295 (23%) Query: 10 LVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLG-----SDIVLQCD 64 LVTG A +L IA+A+H EG + Y + AA L S I +Q D Sbjct: 11 LVTGAAKRL--GSSIAEALHAEGYTVCLHYH--RSAADASTLAATLNARRPNSAITVQAD 66 Query: 65 VAE---------DASID-TMFAELGKV-------WPKFDGFVHSIG-FAPGDQLDGDY-- 104 ++ D S+ T+F+ + W + D V++ F P L D Sbjct: 67 LSNVATASFSETDGSVPVTLFSRCSALVDACYMHWGRCDVLVNNASSFYPTPLLRKDAGE 126 Query: 105 --VNAVTREGFKIA-------HDISSYSFVAMAKACR-------------SMLNPGSALL 142 + +E ++A + I+ Y F+ A A R S++N A+ Sbjct: 127 GGSSVGDKESLEVAAADLFGSNAIAPY-FLIKAFAQRVADTRAEQRGTSYSIVNMVDAMT 185 Query: 143 TLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAG----PIRTLAAS 198 + LG Y + +AK +LE R A + +RVN +S G P + S Sbjct: 186 SQPLLG-------YTMYTMAKEALEGLTRSAALELASLQIRVNGVSPGLSVLP-DDMPFS 237 Query: 199 GIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSI 253 +D+R+ V +R + E+V + FLCS + I+G + VDGG+S+ Sbjct: 238 VQEDYRR------KVPLYQRNSSAEEVSDVVIFLCSPKAKYITGTCIKVDGGYSL 286 >5JS6-A nrPDB Length = 274 Score = 44.7 bits (104), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 49/207 (23%), Positives = 93/207 (44%), Gaps = 25/207 (12%) Query: 41 NDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQL 100 D+ GR E +L + + CDV ++ + T+ +E + + + D V++ G P Q Sbjct: 43 KDESGGRALE--QELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQR 100 Query: 101 DGDYVNAVTREGFKIAHDIS---SYSFVAMA-----KACRSMLNPGSALLTLSYLGAERA 152 + + +GF+ +++ +Y+ +A K+ +++N S + +G +A Sbjct: 101 PEE----TSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNVINISS---LVGAIGQAQA 153 Query: 153 IPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAG----PIRTLAASGIKDFRKMLA 208 +P K ++ A + +A P GVRVN IS G P+ A+ + D R + Sbjct: 154 VPYVAT----KGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIR 209 Query: 209 HCEAVTPIRRTVTIEDVGNSAAFLCSD 235 P+ R +VG +A FL S+ Sbjct: 210 EGMLAQPLGRMGQPAEVGAAAVFLASE 236 >3RSH-A nrPDB Length = 251 Score = 44.7 bits (104), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 64/257 (24%), Positives = 109/257 (42%), Gaps = 27/257 (10%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 L GK LVTG AS+ I IA+ + GA++ T ++ + ++ G + L Sbjct: 10 LEGKVALVTG-ASR-GIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMAL-- 65 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 +V SI+ + + + D V++ G + L + E + + + S Sbjct: 66 NVTNPESIEAVLKAITDEFGGVDILVNNAGITRDNLL-----MRMKEEEWSDIMETNLTS 120 Query: 124 FVAMAKAC-RSML--------NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMA 174 ++KA R M+ N GS + T+ G NY AKA + + MA Sbjct: 121 IFRLSKAVLRGMMKKRQGRIINVGSVVGTMGNAGQ----ANY---AAAKAGVIGFTKSMA 173 Query: 175 NAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCS 234 + GV VN ++ G I T + D ++ + P R ++ ++ AFL S Sbjct: 174 REVASRGVTVNTVAPGFIETDMTKALNDEQRTATLAQ--VPAGRLGDPREIASAVAFLAS 231 Query: 235 DLSAGISGEVVHVDGGF 251 +A I+GE +HV+GG Sbjct: 232 PEAAYITGETLHVNGGM 248 >4NBV-A nrPDB Length = 246 Score = 44.7 bits (104), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 64/264 (24%), Positives = 107/264 (40%), Gaps = 34/264 (12%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDI---- 59 L G+ ++TG A+ I + AQ +GA + D + RV E AA+L + Sbjct: 3 LQGRVAIITGAAA--GIGFATAQRFAEDGAIVVLC---DVQEARVREAAARLAATGATVS 57 Query: 60 VLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDI 119 + DV +D M A + + D V++ G +L +T F D+ Sbjct: 58 AYRVDVTRRDEVDAMVAAVLAAHQRVDILVNNAGITKDARL-----AKMTEAQFDAVIDV 112 Query: 120 SSYSFVAMAKACRSMLN---PGSALLTLSYLG-------AERAIPNYNVMGLAKASLEAN 169 + A+A ++ G L S +G A + V+G K Sbjct: 113 NLKGVFNCAQAVAGLMTEQGKGVILNASSVVGLYGNFGQTNYAASKFGVIGFTKT----- 167 Query: 170 VRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSA 229 A +GP+GVRVNA+ G + T + D K+L + +RR ++ + Sbjct: 168 ---WARELGPKGVRVNAVCPGFVNTEILQTVPD--KVLDGMTSSCWLRRLAEPAEIASIY 222 Query: 230 AFLCSDLSAGISGEVVHVDGGFSI 253 AFL SD ++ ++G + GG S+ Sbjct: 223 AFLASDDASYVNGVAIEASGGMSL 246 >2AE2-A nrPDB Length = 260 Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 29/107 (27%), Positives = 52/107 (48%), Gaps = 11/107 (10%) Query: 152 AIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRT-LAASGIKD------FR 204 A+P V G K +++ R +A + +RVN + G I T L I+D Sbjct: 152 AVPYEAVYGATKGAMDQLTRCLAFEWAKDNIRVNGVGPGVIATSLVEMTIQDPEQKENLN 211 Query: 205 KMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGF 251 K++ C +RR +++ AFLC ++ ++G++++VDGG Sbjct: 212 KLIDRC----ALRRMGEPKELAAMVAFLCFPAASYVTGQIIYVDGGL 254 >5OJG-A nrPDB Length = 260 Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 34/117 (29%), Positives = 58/117 (49%), Gaps = 6/117 (5%) Query: 138 GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAA 197 G+ + SY A ++ P G+ K +L R +A + + +RVN I+ G I+T + Sbjct: 141 GAIIFNASY-SAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRVNGIAPGVIKTKMS 199 Query: 198 S----GIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGG 250 G +D K L + + R V +D + A+L SD S+ I+GE++ + GG Sbjct: 200 QVLWDGGEDAEKELTDIQEIALGRLGVP-DDCAGTVAYLASDDSSYITGEMIIIAGG 255 >3UN1-A nrPDB Length = 260 Score = 43.9 bits (102), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 54/201 (26%), Positives = 85/201 (42%), Gaps = 36/201 (17%) Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIG------FAPGDQLDGDYVNAVTREGFKIAH 117 D+++ + D + E + + + D V++ G F Q D D+ V GF Sbjct: 76 DISKPETADRIVREGIERFGRIDSLVNNAGVFLAKPFVEMTQEDYDHNLGVNVAGF---- 131 Query: 118 DISSYSFVAMAKACRSMLNPGS--------ALLTLSYLGAERAIPNYNVMGLAKASLEAN 169 F +A ML GS +L+ +G A+ + L K L A Sbjct: 132 ------FHITQRAAAEMLKQGSGHIVSITTSLVDQPMVGMPSALAS-----LTKGGLNAV 180 Query: 170 VRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSA 229 R +A GVRVNA+S G I+T + LA + P+ R I DV ++ Sbjct: 181 TRSLAMEFSRSGVRVNAVSPGVIKTPMHPA--ETHSTLA---GLHPVGRMGEIRDVVDAV 235 Query: 230 AFLCSDLSAGISGEVVHVDGG 250 +L + + I+GE++HVDGG Sbjct: 236 LYL--EHAGFITGEILHVDGG 254 >2BGM-A nrPDB Length = 278 Score = 43.5 bits (101), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 57/204 (27%), Positives = 89/204 (43%), Gaps = 21/204 (10%) Query: 61 LQCDVAEDASI----DTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIA 116 + CDV +D + DT A+ GK+ F G V + P L+ E FK Sbjct: 69 VHCDVTKDEDVRNLVDTTIAKHGKLDIMF-GNVGVLSTTPYSILEAG------NEDFKRV 121 Query: 117 HDISSY-SFVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYM 173 DI+ Y +F+ A R M+ GS + T S +V K ++ + Sbjct: 122 MDINVYGAFLVAKHAARVMIPAKKGSIVFTASISSFTAGEGVSHVYTATKHAVLGLTTSL 181 Query: 174 ANAMGPEGVRVNAIS----AGPIRTLAASGIKDFR-KMLAHCEAVTPIRRTVTIEDVGNS 228 +G G+RVN +S A P+ T G+ R + LAH +A + EDV ++ Sbjct: 182 CTELGEYGIRVNCVSPYIVASPLLT-DVFGVDSSRVEELAH-QAANLKGTLLRAEDVADA 239 Query: 229 AAFLCSDLSAGISGEVVHVDGGFS 252 A+L D S +SG + +DGG++ Sbjct: 240 VAYLAGDESKYVSGLNLVIDGGYT 263 >2AG5-A nrPDB Length = 246 Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 63/267 (23%), Positives = 114/267 (42%), Gaps = 36/267 (13%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 60 MG L GK I++T A + A +A A REGA++ T N+ +E++ + + ++ Sbjct: 1 MGRLDGKVIILTAAAQGIGQAAALAFA--REGAKVIATDINESKLQELEKYPG-IQTRVL 57 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFD--GFVHSIGFAPGDQLDGDYVNAVTREGFKIAHD 118 DV + ID E+ ++ F+ GFVH ++ D D F + + Sbjct: 58 ---DVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWD---------FSMNLN 105 Query: 119 ISSYSFVAMAKACRSMLNPGSALLTLSYLGAE-RAIPNYNVMGLAKASLEANVRYMANAM 177 + S + A + + ++ +S + + + + N V KA++ + +A Sbjct: 106 VRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADF 165 Query: 178 GPEGVRVNAISAGPIRT------LAASG-----IKDFRKMLAHCEAVTPIRRTVTIEDVG 226 +G+R N + G + T + A G DF K R T E++ Sbjct: 166 IQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKR-------QKTGRFATAEEIA 218 Query: 227 NSAAFLCSDLSAGISGEVVHVDGGFSI 253 +L SD SA ++G V +DGG+S+ Sbjct: 219 MLCVYLASDESAYVTGNPVIIDGGWSL 245 >1YXM-A nrPDB Length = 303 Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 56/269 (20%), Positives = 116/269 (43%), Gaps = 32/269 (11%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAF-----TYQNDKLKGRVEEFAAQLG 56 G L G+ +VTG A+ GI +A+ +E EL + + ++LK +E A L Sbjct: 14 GLLQGQVAIVTGGAT------GIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLP 67 Query: 57 SD-----IVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIG---FAPGDQLDGDYVNAV 108 I +QC++ + ++ + + K + V++ G +P + + +AV Sbjct: 68 PTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAV 127 Query: 109 TREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEA 168 + +++ ++ A M G +++ + + + P G A+A + Sbjct: 128 ------LETNLTGTFYMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYN 180 Query: 169 NVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDF----RKMLAHCEAVTPIRRTVTIED 224 + +A G+R+N ++ G I + A ++++ + P +R E+ Sbjct: 181 LTKSLALEWACSGIRINCVAPGVIYSQTA--VENYGSWGQSFFEGSFQKIPAKRIGVPEE 238 Query: 225 VGNSAAFLCSDLSAGISGEVVHVDGGFSI 253 V + FL S ++ I+G+ V VDGG S+ Sbjct: 239 VSSVVCFLLSPAASFITGQSVDVDGGRSL 267 >5U9P-A nrPDB Length = 265 Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 68/266 (25%), Positives = 112/266 (42%), Gaps = 34/266 (12%) Query: 4 LSGKRILVTGVASK--LSIAYGIAQAMHREGAELAFTYQNDK------LKGRVEEFAAQL 55 L G+R L+TG L++A G+A+A GA + +N++ + R E FAA Sbjct: 18 LDGRRALITGSGRGIGLTLARGLAEA----GAAIVINDRNEEKAATLARRFRDEGFAADH 73 Query: 56 GSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGF---APGDQLDGDYVNAVTREG 112 DVAE A + E D V++ G AP D + D +A+ R Sbjct: 74 AV-----FDVAEHAQVRAAIDEFEARVGAIDILVNNAGIQRRAPLDAFEPDDWHALMRV- 127 Query: 113 FKIAHDISSYSFVAMAKACRSMLNPGSA-LLTLSYLGAERAIPNYNVMGLAKASLEANVR 171 ++ VA A A R M+ G ++ + + +E A P K ++ + Sbjct: 128 -----NLDGVFNVAQAVA-RHMIARGHGKIINICSVQSELARPTIAPYAATKGAVRMLTK 181 Query: 172 YMANAMGPEGVRVNAISAGPIRTLAASGIKD---FRKMLAHCEAVTPIRRTVTIEDVGNS 228 M G++ N ++ G T + D F L C+ TP R ++++ + Sbjct: 182 GMCADWARYGIQANGLAPGYFETELNRALVDDAAFSDWL--CKR-TPAGRWGQVDELCGA 238 Query: 229 AAFLCSDLSAGISGEVVHVDGGFSIA 254 A FL S S ++G+ + VDGG + A Sbjct: 239 AIFLASAASDFVNGQTLFVDGGLTSA 264 >1GEE-A nrPDB Length = 261 Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 51/259 (19%), Positives = 109/259 (42%), Gaps = 20/259 (7%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 L GK +++TG ++ L + I A + + + + D+ +EE G I ++ Sbjct: 5 LEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKVGGEAIAVKG 64 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGF------KIAH 117 DV ++ + + K + K D +++ G N V+ K+ Sbjct: 65 DVTVESDVINLVQSAIKEFGKLDVMINNAGLE----------NPVSSHEMSLSDWNKVID 114 Query: 118 DISSYSFVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMAN 175 + +F+ +A + + + ++ +S + + P + +K ++ +A Sbjct: 115 TNLTGAFLGSREAIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLAL 174 Query: 176 AMGPEGVRVNAISAGPIRT-LAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCS 234 P+G+RVN I G I T + A D + A E++ P+ E++ AA+L S Sbjct: 175 EYAPKGIRVNNIGPGAINTPINAEKFADPEQR-ADVESMIPMGYIGEPEEIAAVAAWLAS 233 Query: 235 DLSAGISGEVVHVDGGFSI 253 ++ ++G + DGG ++ Sbjct: 234 SEASYVTGITLFADGGMTL 252 >3AUT-A nrPDB Length = 269 Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 58/260 (22%), Positives = 111/260 (42%), Gaps = 24/260 (9%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDK-----LKGRVEEFAAQLGSD 58 L K +++TG ++ L A +A +E A++ Y N++ K VEE Q Sbjct: 13 LKDKVVVITGGSTGLGRA--MAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQA--- 67 Query: 59 IVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGF---APGDQLDGDYVNAVTREGFKI 115 I++Q DV ++ + + K + D +++ G P +L D N V Sbjct: 68 IIVQGDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNL-- 125 Query: 116 AHDISSYSFVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYM 173 + +F+ +A + + + ++ +S + P + +K ++ + Sbjct: 126 -----TGAFLGSREAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETL 180 Query: 174 ANAMGPEGVRVNAISAGPIRT-LAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFL 232 A P+G+RVN I G + T + A D + A E++ P+ E+V AAFL Sbjct: 181 ALEYAPKGIRVNNIGPGAMNTPINAEKFADPVQR-ADVESMIPMGYIGKPEEVAAVAAFL 239 Query: 233 CSDLSAGISGEVVHVDGGFS 252 S ++ ++G + DGG + Sbjct: 240 ASSQASYVTGITLFADGGMT 259 >1FJH-A nrPDB Length = 257 Score = 41.2 bits (95), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 29/91 (31%), Positives = 47/91 (51%), Gaps = 1/91 (1%) Query: 162 AKASLEANVRYMANAMGPEGVRVNAISAGPIRT-LAASGIKDFRKMLAHCEAVTPIRRTV 220 +K +L VR A A G GVR+N I+ G T L +G++D R + + V P+ R Sbjct: 158 SKNALTVAVRKRAAAWGEAGVRLNTIAPGATETPLLQAGLQDPRYGESIAKFVPPMGRRA 217 Query: 221 TIEDVGNSAAFLCSDLSAGISGEVVHVDGGF 251 ++ + AFL S ++ + G + +DGG Sbjct: 218 EPSEMASVIAFLMSPAASYVHGAQIVIDGGI 248 >5ITV-A nrPDB Length = 255 Score = 41.2 bits (95), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 55/261 (21%), Positives = 104/261 (39%), Gaps = 24/261 (9%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV--L 61 L+ K +L+TG AS I Y QA + A + D + + E + +D + + Sbjct: 5 LTDKTVLITGGAS--GIGYAAVQAFLGQQANVVVA---DIDEAQGEAMVRKENNDRLHFV 59 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGF---APGDQLDGDYVNAVTREGFKIAHD 118 Q D+ ++A+ + D +++ G AP +++ N V + Sbjct: 60 QTDITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNL----- 114 Query: 119 ISSYSFVAMAKACRSMLNPGSA-LLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAM 177 + F+ A + ML G ++ +G A P+ +K + + MA Sbjct: 115 --TGMFLMSKHALKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDY 172 Query: 178 GPEGVRVNAISAGPI------RTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAF 231 +RVN + G I ++ + ++ V P+ R E++ N F Sbjct: 173 AKHQIRVNCVCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRLGKPEEIANVMLF 232 Query: 232 LCSDLSAGISGEVVHVDGGFS 252 L SDLS+ ++G + DGG++ Sbjct: 233 LASDLSSYMTGSAITADGGYT 253 >3F9I-A nrPDB Length = 249 Score = 40.8 bits (94), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 54/254 (21%), Positives = 114/254 (44%), Gaps = 25/254 (9%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQ- 62 L+GK L+TG +S I IA+ +H+ G+++ + N++ +++ L + ++ Sbjct: 12 LTGKTSLITGASS--GIGSAIARLLHKLGSKVIISGSNEE---KLKSLGNALKDNYTIEV 66 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS-S 121 C++A + ++ D V + G D L + + F DI+ Sbjct: 67 CNLANKEECSNLISK----TSNLDILVCNAGITS-DTL----AIRMKDQDFDKVIDINLK 117 Query: 122 YSFVAMAKACRSMLNPGSA-LLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 +F+ +A + M+ ++ +S + P +KA L + ++ + Sbjct: 118 ANFILNREAIKKMIQKRYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYEVATR 177 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVT---PIRRTVTIEDVGNSAAFLCSDLS 237 G+ VNA++ G I++ + + ++ EA+ P+ EDV + AFL S+ + Sbjct: 178 GITVNAVAPGFIKSDMTDKLNEKQR-----EAIVQKIPLGTYGIPEDVAYAVAFLASNNA 232 Query: 238 AGISGEVVHVDGGF 251 + I+G+ +HV+GG Sbjct: 233 SYITGQTLHVNGGM 246 >2X9N-A nrPDB Length = 288 Score = 40.8 bits (94), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 64/272 (23%), Positives = 112/272 (41%), Gaps = 41/272 (15%) Query: 10 LVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSD---------IV 60 +VTG A + I IA +H+ G + Y N E A L + +V Sbjct: 27 VVTGAAKR--IGRAIAVKLHQTGYRVVIHYHNSA------EAAVSLADELNKERSNTAVV 78 Query: 61 LQCDVAED----ASIDTMFAELGKVWPKFDGFVHSI-GFAPGDQLDGDY---VNAVTREG 112 Q D+ AS + + + + + D V++ F P + GD+ N T E Sbjct: 79 CQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDNSNGKTVE- 137 Query: 113 FKIAHDISSYS----FVAMAKACRSM-LNPGSALLTLSYLGAERAIPN-----YNVMGLA 162 ++A I + + + M+ A R NP LS + A+ + +++ + Sbjct: 138 TQVAELIGTNAIAPFLLTMSFAQRQKGTNPNCTSSNLSIVNLCDAMVDQPCMAFSLYNMG 197 Query: 163 KASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPI-RRTVT 221 K +L + A + P G+RVN ++ G A G ++ K P+ RR + Sbjct: 198 KHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKW----RRKVPLGRREAS 253 Query: 222 IEDVGNSAAFLCSDLSAGISGEVVHVDGGFSI 253 E + ++ FL S + I+G ++ VDGG S+ Sbjct: 254 AEQIADAVIFLVSGSAQYITGSIIKVDGGLSL 285 >4BO1-A nrPDB Length = 269 Score = 40.8 bits (94), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 72/262 (27%), Positives = 110/262 (41%), Gaps = 34/262 (12%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV--- 60 L GK LVTG AS+ I IA + R GA + T + E+ A L ++ V Sbjct: 25 LQGKVALVTG-ASR-GIGQAIALELGRLGAVVIGTATSAS---GAEKIAETLKANGVEGA 79 Query: 61 -LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQL----DGDYVNAVTREGFKI 115 L DV+ D S+ + + + V++ G + L D ++ + V Sbjct: 80 GLVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEWFDVVNTN-LNS 138 Query: 116 AHDISSYSFVAMAKA-CRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMA 174 + +S M KA ++N GS + + G NY AKA LE R +A Sbjct: 139 LYRLSKAVLRGMTKARWGRIINIGSVVGAMGNAGQ----TNYAA---AKAGLEGFTRALA 191 Query: 175 NAMGPEGVRVNAISAGPIRTLAASGIKDFRKML--AHCEAV---TPIRRTVTIEDVGNSA 229 +G + VNA++ G I T D + L A EA+ P+ R E++ Sbjct: 192 REVGSRAITVNAVAPGFIDT-------DMTRELPEAQREALLGQIPLGRLGQAEEIAKVV 244 Query: 230 AFLCSDLSAGISGEVVHVDGGF 251 FL SD +A ++G V V+GG Sbjct: 245 GFLASDGAAYVTGATVPVNGGM 266 >1X1T-A nrPDB Length = 260 Score = 40.8 bits (94), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 29/86 (33%), Positives = 46/86 (53%), Gaps = 16/86 (18%) Query: 180 EGVRVNAISAGPIRT------LAASGIKD-------FRKMLAHCEAVTPIRRTVTIEDVG 226 +G+ NAI G +RT ++A K+ R++L+ + P + VT E +G Sbjct: 176 QGITANAICPGWVRTPLVEKQISALAEKNGVDQETAARELLSEKQ---PSLQFVTPEQLG 232 Query: 227 NSAAFLCSDLSAGISGEVVHVDGGFS 252 +A FL SD +A I+G V VDGG++ Sbjct: 233 GTAVFLASDAAAQITGTTVSVDGGWT 258 >4EGF-A nrPDB Length = 266 Score = 40.4 bits (93), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 29/116 (25%), Positives = 57/116 (49%) Query: 138 GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAA 197 G A++T++ A +P++ +KA L + +A +GP G+R N++ + T Sbjct: 150 GGAIITVASAAALAPLPDHYAYCTSKAGLVMATKVLARELGPHGIRANSVCPTVVLTEMG 209 Query: 198 SGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSI 253 + A A P+ R +V ++ +L SD ++ I+G + VDGG+++ Sbjct: 210 QRVWGDEAKSAPMIARIPLGRFAVPHEVSDAVVWLASDAASMINGVDIPVDGGYTM 265 >2FWM-X nrPDB Length = 250 Score = 40.4 bits (93), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 57/262 (21%), Positives = 107/262 (40%), Gaps = 26/262 (9%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 SGK + VTG I Y A LAF K+ G + F + Sbjct: 5 FSGKNVWVTGAGK--GIGYATA---------LAFVEAGAKVTGFDQAFTQEQYPFATEVM 53 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 DVA+ A + + L + D V++ G L + +++E ++ ++ Sbjct: 54 DVADAAQVAQVCQRLLAETERLDALVNAAGI-----LRMGATDQLSKEDWQQTFAVNVGG 108 Query: 124 FVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 + + + G A++T++ A + G +KA+L++ + + G Sbjct: 109 AFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSG 168 Query: 182 VRVNAISAGPI-----RTLAASGIKDFRKMLAHCEAVT---PIRRTVTIEDVGNSAAFLC 233 VR N +S G RTL S + +++ E P+ + +++ N+ FL Sbjct: 169 VRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLA 228 Query: 234 SDLSAGISGEVVHVDGGFSIAA 255 SDL++ I+ + + VDGG ++ A Sbjct: 229 SDLASHITLQDIVVDGGSTLGA 250 >4Z9Y-A nrPDB Length = 253 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 31/108 (28%), Positives = 50/108 (46%), Gaps = 4/108 (3%) Query: 144 LSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDF 203 LS+ G R +P+Y +K+++ R MAN G+ VNAI+ G + T ++ Sbjct: 147 LSFQGGIR-VPSYTA---SKSAVMGVTRLMANEWAKHGINVNAIAPGYMATNNTQQLRAD 202 Query: 204 RKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGF 251 + P R +D+ + FL S S I+G + VDGG+ Sbjct: 203 EERSKEILDRIPAGRWGLPQDLMGPSVFLASSASDYINGYTIAVDGGW 250 >5B1Y-A nrPDB Length = 270 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 49/230 (21%), Positives = 102/230 (44%), Gaps = 16/230 (6%) Query: 30 REGAELAFTYQND-KLKGRVEEFAAQLGSD--IVLQCDVAEDASIDTMFAELGKVWPKFD 86 REG + Y++ L + E A +LGS ++ DV + S+ M + +G++ P + Sbjct: 45 REGWSVVIAYKSRADLAEKTAEEARRLGSPEAYTVRVDVGDPDSVTEMSSRVGELIPHLN 104 Query: 87 GFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSY 146 V++ G QL G +++ + +++ V ++++ ++ Sbjct: 105 VLVNAAGVL---QLGGIEETSISEWEETLRVNLTGVYLVTKLLLPLLRKAKWASIVNVAS 161 Query: 147 LGAERAIPNYNVM-GLAKASLEANV----RYMANAMGPEGVRVNAISAGPIRTLAASGIK 201 + E NV+ G+A ++ +A V + +A + G+RVNA++ + T Sbjct: 162 IAGETG----NVVAGVAYSASKAGVIGLTKRLAVQLAGYGIRVNAVAPSFVETDMTRSFL 217 Query: 202 DFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSD-LSAGISGEVVHVDGG 250 D + ++ P++ + EDV + FL S GI+G V+ ++ G Sbjct: 218 DTPEKRERIASLHPLKIILKPEDVAEAILFLADPRRSRGITGHVLSINAG 267 >1H5Q-A nrPDB Length = 265 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 50/208 (24%), Positives = 89/208 (42%), Gaps = 35/208 (16%) Query: 62 QCDVAED----ASIDTMFAELGKVWPKFDGFVHSIGFA---PGDQLDGDYVNAVTREGFK 114 QCDV+ +I + A+LG + G + + G + P +L T E F Sbjct: 70 QCDVSNTDIVTKTIQQIDADLGPI----SGLIANAGVSVVKPATEL--------THEDFA 117 Query: 115 IAHDISSYSFV----AMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGL--------A 162 +D++ + A+AK GS ++T S + + I ++ G + Sbjct: 118 FVYDVNVFGVFNTCRAVAKLWLQKQQKGSIVVTSSM--SSQIINQSSLNGSLTQVFYNSS 175 Query: 163 KASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTI 222 KA+ V+ +A G+RVNA+S G + T + + +K+ H + P+ R Sbjct: 176 KAACSNLVKGLAAEWASAGIRVNALSPGYVNTDQTAHMD--KKIRDHQASNIPLNRFAQP 233 Query: 223 EDVGNSAAFLCSDLSAGISGEVVHVDGG 250 E++ A L SD + ++G +DGG Sbjct: 234 EEMTGQAILLLSDHATYMTGGEYFIDGG 261 >4DA9-A nrPDB Length = 280 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 67/248 (27%), Positives = 106/248 (42%), Gaps = 35/248 (14%) Query: 25 AQAMHREGAELAFTYQNDK--LKGRVEEFAAQLGSDIVLQCDVAE----DASIDTMFAEL 78 A+A+ G ++A T D + + E + I L+ D+A+ A++D + AE Sbjct: 46 ARALAASGFDIAITGIGDAEGVAPVIAELSGLGARVIFLRADLADLSSHQATVDAVVAEF 105 Query: 79 GKVWPKFDGFVHSIGFAP---GDQLDGDYVNAVTREGFKIAHDI--SSYSFVAM----AK 129 G++ D V++ G A D LD N T G + + + AM A+ Sbjct: 106 GRI----DCLVNNAGIASIVRDDFLDLKPENFDTIVGVNLRGTVFFTQAVLKAMLASDAR 161 Query: 130 ACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISA 189 A RS++N ++ + A P ++KA L A + +A + G+ V + Sbjct: 162 ASRSIIN-------ITSVSAVMTSPERLDYCMSKAGLAAFSQGLALRLAETGIAVFEVRP 214 Query: 190 GPIR---TLAASGIKDFRKMLAHCEA-VTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVV 245 G IR T A SG D E+ + P+RR ED+GN A L +G V+ Sbjct: 215 GIIRSDMTAAVSGKYD-----GLIESGLVPMRRWGEPEDIGNIVAGLAGGQFGFATGSVI 269 Query: 246 HVDGGFSI 253 DGG SI Sbjct: 270 QADGGLSI 277 >2C07-A nrPDB Length = 285 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 29/91 (31%), Positives = 45/91 (49%), Gaps = 2/91 (2%) Query: 162 AKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVT 221 +KA + + +A + + VNAI+ G I + I + ++ + + P R T Sbjct: 196 SKAGVIGFTKSLAKELASRNITVNAIAPGFISSDMTDKISE--QIKKNIISNIPAGRMGT 253 Query: 222 IEDVGNSAAFLCSDLSAGISGEVVHVDGGFS 252 E+V N A FL SD S I+G V +DGG S Sbjct: 254 PEEVANLACFLSSDKSGYINGRVFVIDGGLS 284 >2Q2Q-A nrPDB Length = 255 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 65/255 (25%), Positives = 101/255 (39%), Gaps = 11/255 (4%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 L GK LVTG S I GIAQ + R GA + D + E A + Sbjct: 2 LKGKTALVTGSTS--GIGLGIAQVLARAGANIVLNGFGDPAPA-LAEIARHGVKAVHHPA 58 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGF---APGDQLDGDYVNAVTREGFKIAHDIS 120 D+++ A I+ +FA + + D V++ G AP +Q + + + + Sbjct: 59 DLSDVAQIEALFALAEREFGGVDILVNNAGIQHVAPVEQFPLESWDKIIALNLSAVFHGT 118 Query: 121 SYSFVAM-AKACRSMLNPGSALLTLSYLG-AERAIPNYNVMGLAKA-SLE-ANVRYMANA 176 + M A+ ++N S + G A + V+GL K LE A NA Sbjct: 119 RLALPGMRARNWGRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGLETATSNVTCNA 178 Query: 177 MGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDL 236 + P G + + I AA+G + P VT E +G FLCS+ Sbjct: 179 ICP-GWVLTPLVQKQIDDRAANGGDPLQAQHDLLAEKQPSLAFVTPEHLGELVLFLCSEA 237 Query: 237 SAGISGEVVHVDGGF 251 + + G +VDGG+ Sbjct: 238 GSQVRGAAWNVDGGW 252 >5JY1-A nrPDB Length = 274 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 34/110 (30%), Positives = 50/110 (45%), Gaps = 16/110 (14%) Query: 155 NYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCE--- 211 +YN AKA + R A+ G + VNAI+ A G F + E Sbjct: 163 DYNT---AKAGIVGLTRSAASEWGRFNITVNAIAP------TAMGATFFELAAKNPEFAE 213 Query: 212 ---AVTPIRRTVTIE-DVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMN 257 A P+ R+ E D+G +A F S++S ++GE +HVDGG + N Sbjct: 214 RSAAARPLGRSGDPEQDIGPAAVFFASEMSRFVTGETLHVDGGLHLPGYN 263 >3EZL-A nrPDB Length = 256 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 58/245 (23%), Positives = 102/245 (41%), Gaps = 23/245 (9%) Query: 20 IAYGIAQAMHREGAEL-AFTYQNDKLKGRVEEFAAQLGSDI------VLQCDVAEDASID 72 I I Q +H++G + A N + + E LG D V D + A D Sbjct: 25 IGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYASEGNVGDWDSTKQA-FD 83 Query: 73 TMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYV-NAVTREGFKIAHDISSYSFVAMAKAC 131 + AE+G++ D V++ G D V +TRE ++ D + S + K Sbjct: 84 KVKAEVGEI----DVLVNNAGITR------DVVFRKMTREDWQAVIDTNLTSLFNVTKQV 133 Query: 132 -RSMLNPGSA-LLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISA 189 M+ G ++ +S + ++ AKA + +A + +GV VN +S Sbjct: 134 IDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVATKGVTVNTVSP 193 Query: 190 GPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDG 249 G I T I+ +L A P+RR + +++G+ A+L S+ S +G ++G Sbjct: 194 GYIGTDMVKAIRP--DVLEKIVATIPVRRLGSPDEIGSIVAWLASEESGFSTGADFSLNG 251 Query: 250 GFSIA 254 G + Sbjct: 252 GLHMG 256 >5EJ2-A nrPDB Length = 308 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 36/126 (28%), Positives = 54/126 (42%), Gaps = 14/126 (11%) Query: 138 GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAA 197 GS +LT S +G +A PN AK + +R A +GP +RVNA+ + T Sbjct: 180 GSIVLT-SSVGGRKAYPNTGHYIAAKHGVIGLMRAFAVELGPHMIRVNAVLPTQVSTTMV 238 Query: 198 SGIKDFRKMLAHCEAVTP--------IRRTVTI-----EDVGNSAAFLCSDLSAGISGEV 244 + FR E P + T+ + D+ N+ FL SD S ++G Sbjct: 239 MNDQTFRLFRPDLENPGPDDFAPISQMMHTLPVPWVDASDISNAVLFLASDESRYVTGVS 298 Query: 245 VHVDGG 250 + VD G Sbjct: 299 LPVDAG 304 >2PH3-A nrPDB Length = 245 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 69/263 (26%), Positives = 107/263 (40%), Gaps = 38/263 (14%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTY-QNDKLKGRVEEFAAQLGSDIV--LQC 63 ++ L+TG AS+ I IA + +G LA Y QN + V E A + GS +V L Sbjct: 2 RKALITG-ASR-GIGRAIALRLAEDGFALAIHYGQNREKAEEVAEEARRRGSPLVAVLGA 59 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQL----DGDY----------VNAVT 109 ++ E + + + +V D V++ G L D D+ V T Sbjct: 60 NLLEAEAATALVHQAAEVLGGLDTLVNNAGITRDTLLVRMKDEDWEAVLEANLSAVFRTT 119 Query: 110 REGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEAN 169 RE K+ V + + NPG A NY +KA L Sbjct: 120 REAVKLMMKARFGRIVNITSVVGILGNPGQA--------------NYVA---SKAGLIGF 162 Query: 170 VRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSA 229 R +A G+ VNA++ G I T + K A+ + + P R E+V + Sbjct: 163 TRAVAKEYAQRGITVNAVAPGFIETEMTERLPQEVKE-AYLKQI-PAGRFGRPEEVAEAV 220 Query: 230 AFLCSDLSAGISGEVVHVDGGFS 252 AFL S+ + I+G+ + VDGG + Sbjct: 221 AFLVSEKAGYITGQTLCVDGGLT 243 >4IS3-A nrPDB Length = 268 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 47/192 (24%), Positives = 87/192 (45%), Gaps = 22/192 (11%) Query: 70 SIDTMFAELGKVWPKF---DGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS---YS 123 S D + A +G+V K+ D +++ G + + V+ E FK DI+ ++ Sbjct: 87 SRDAVMAAVGQVAQKYGRLDVMINNAGIT-----SNNVFSRVSEEEFKHIMDINVTGVFN 141 Query: 124 FVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE--- 180 A C G + T S G ++ G+ + +A+V + + +G E Sbjct: 142 GAWCAYQCMKDAKKGVIINTASVTGIFGSLS-----GVGYPASKASVIGLTHGLGREIIR 196 Query: 181 -GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAG 239 +RV ++ G + T +G M + +A+ P++R + E++ N FL SDL++G Sbjct: 197 KNIRVVGVAPGVVNTDMTNG-NPPEIMEGYLKAL-PMKRMLEPEEIANVYLFLASDLASG 254 Query: 240 ISGEVVHVDGGF 251 I+ V VDG + Sbjct: 255 ITATTVSVDGAY 266 >4IIV-A nrPDB Length = 267 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 60/257 (23%), Positives = 105/257 (40%), Gaps = 29/257 (11%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGR--VEEFAAQLGSDIVLQCD 64 + +LVTG ASK I IA+ + +G + Y D + + A G+ +L D Sbjct: 27 RSVLVTG-ASK-GIGRAIARQLAADGFNIGVHYHRDAAGAQETLNAIVANGGNGRLLSFD 84 Query: 65 VAEDASIDTMFAELGKVWPKFDGFVHSIGFAPG---DQLDGDYVNAVTREGFKIAHDISS 121 VA + + G V + G A L D +AV +++ Sbjct: 85 VANREQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPALSNDDWDAVIHTNLDSFYNVIQ 144 Query: 122 YSFVAMAKACRSMLNPGSALLTLSYLGA---ERAIPNYNVMGLAKASLEANVRYMANAMG 178 + M A G ++TLS + R NY+ AKA + + +A + Sbjct: 145 PCIMPMIGA-----RQGGRIITLSSVSGVMGNRGQVNYSA---AKAGIIGATKALAIELA 196 Query: 179 PEGVRVNAISAGPIRT----LAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCS 234 + VN I+ G I T + S +K+ M+ P++R E+V A++L S Sbjct: 197 KRKITVNCIAPGLIDTGMIEMEESALKEAMSMI-------PMKRMGQAEEVAGLASYLMS 249 Query: 235 DLSAGISGEVVHVDGGF 251 D++ ++ +V+ ++GG Sbjct: 250 DIAGYVTRQVISINGGM 266 >3A28-C nrPDB Length = 258 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 59/259 (22%), Positives = 106/259 (40%), Gaps = 22/259 (8%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELA---FTYQNDKLKGRVEEFAAQLGSDIVLQC 63 K +VTG A I GI++ + +G ++A Q ++ ++ A + + Sbjct: 3 KVAMVTGGAQ--GIGRGISEKLAADGFDIAVADLPQQEEQAAETIKLIEAADQKAVFVGL 60 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 DV + A+ D+ E + FD V++ G A L VT E K + ++ +S Sbjct: 61 DVTDKANFDSAIDEAAEKLGGFDVLVNNAGIAQIKPL-----LEVTEEDLKQIYSVNVFS 115 Query: 124 -FVAMAKACRSM--LNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 F + A R L ++ + + A + P + K ++ + A + P+ Sbjct: 116 VFFGIQAASRKFDELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQELAPK 175 Query: 181 GVRVNAISAGPIRT---------LAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAF 231 G VNA + G + T L+ K + + + R EDV +F Sbjct: 176 GHTVNAYAPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSF 235 Query: 232 LCSDLSAGISGEVVHVDGG 250 L S+ S ++G+V+ VDGG Sbjct: 236 LASENSNYVTGQVMLVDGG 254 >2B4Q-A nrPDB Length = 276 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 56/257 (21%), Positives = 102/257 (39%), Gaps = 14/257 (5%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 L+G+ LVTG I IAQ + GA + ++ + + G + Sbjct: 27 LAGRIALVTG--GSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYGDCQAIPA 84 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 D++ +A + LG++ + D V++ G + G L+ V+ G++ ++ S Sbjct: 85 DLSSEAGARRLAQALGELSARLDILVNNAGTSWGAALESYPVS-----GWEKVMQLNVTS 139 Query: 124 FVAMAKACRSML-------NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANA 176 + + +L NP + S G G +KA+L R +A Sbjct: 140 VFSCIQQLLPLLRRSASAENPARVINIGSVAGISAMGEQAYAYGPSKAALHQLSRMLAKE 199 Query: 177 MGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDL 236 + E + VN I+ G + I + + L A P+ R E++ A L Sbjct: 200 LVGEHINVNVIAPGRFPSRMTRHIANDPQALEADSASIPMGRWGRPEEMAALAISLAGTA 259 Query: 237 SAGISGEVVHVDGGFSI 253 A ++G V+ +DGGF + Sbjct: 260 GAYMTGNVIPIDGGFHL 276 >3RWB-A nrPDB Length = 247 Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust. Identities = 56/256 (21%), Positives = 101/256 (39%), Gaps = 23/256 (8%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 L+GK LVTG A I IA + +GA + + N + + I Sbjct: 4 LAGKTALVTGAAQ--GIGKAIAARLAADGATVIVSDINAEGAKAAAASIGKKARAIA--A 59 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAP---GDQLDGDYVNAVTREGFKIAHDIS 120 D+++ S+ +FAE+ + D V++ P D +D D+ + D++ Sbjct: 60 DISDPGSVKALFAEIQALTGGIDILVNNASIVPFVAWDDVDLDHWRKII--------DVN 111 Query: 121 -SYSFVAMAKACRSMLNPGSALLTLSYLGAE--RAIPNYNVMGLAKASLEANVRYMANAM 177 + +F+ M G A +S PN AK + R +A + Sbjct: 112 LTGTFIVTRAGTDQMRAAGKAGRVISIASNTFFAGTPNMAAYVAAKGGVIGFTRALATEL 171 Query: 178 GPEGVRVNAISAGPIRTLAASGIK--DFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSD 235 G + NA++ G I + G+K + E + ++ E + + +FL SD Sbjct: 172 GKYNITANAVTPGLIES---DGVKASPHNEAFGFVEMLQAMKGKGQPEHIADVVSFLASD 228 Query: 236 LSAGISGEVVHVDGGF 251 + I+G+ ++VD G Sbjct: 229 DARWITGQTLNVDAGM 244 >3GDF-A nrPDB Length = 267 Score = 37.7 bits (86), Expect = 0.005, Method: Compositional matrix adjust. Identities = 68/266 (25%), Positives = 111/266 (41%), Gaps = 35/266 (13%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKG---RVEEFAAQLG-SDI 59 L GK ++VTG + + A+ GA +A TY + + +G V+E G Sbjct: 18 LKGKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYAS-RAQGAEENVKELEKTYGIKAK 76 Query: 60 VLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQ--LDGDYVNAVTREGFKIAH 117 +C V S + + ++ + + D F+ + G A D LDG + E + Sbjct: 77 AYKCQVDSYESCEKLVKDVVADFGQIDAFIANAG-ATADSGILDG------SVEAWNHVV 129 Query: 118 DISSYSFVAMAKACRSMLN---PGSALLTLSYLGAERAIP----NYNVMGLAKASLEANV 170 + AKA GS ++T S G P +YNV AKA Sbjct: 130 QVDLNGTFHCAKAVGHHFKERGTGSLVITASMSGHIANFPQEQTSYNV---AKAGCIHMA 186 Query: 171 RYMANAMGPEGVRVNAISAGPIRTLAASGIKDF----RKMLAHCEAVTPIRRTVTIEDVG 226 R +AN + RVN+IS G I T G+ DF + L H ++ P+ R +++ Sbjct: 187 RSLANEW-RDFARVNSISPGYIDT----GLSDFVPKETQQLWH--SMIPMGRDGLAKELK 239 Query: 227 NSAAFLCSDLSAGISGEVVHVDGGFS 252 + + SD S +G + +DGG++ Sbjct: 240 GAYVYFASDASTYTTGADLLIDGGYT 265 >4CQL-A nrPDB Length = 261 Score = 37.4 bits (85), Expect = 0.006, Method: Compositional matrix adjust. Identities = 49/204 (24%), Positives = 85/204 (41%), Gaps = 19/204 (9%) Query: 56 GSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQL-------DGDYVNAV 108 G+ Q DV+E + + ++ + + V S D+ D D V AV Sbjct: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAV 126 Query: 109 TREGFKIAHDISSYSFVAMAKACR-SMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLE 167 +G + ++ + V+ CR S++N S + + +G NY +KA + Sbjct: 127 NLKGTFLVTQAAAQALVS--NGCRGSIINISSIVGKVGNVGQT----NYAA---SKAGVI 177 Query: 168 ANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGN 227 + A +G G+R N++ G I T + +K++ + P+ EDV + Sbjct: 178 GLTQTAARELGRHGIRCNSVLPGFIATPMTQKVP--QKVVDKITEMIPMGHLGDPEDVAD 235 Query: 228 SAAFLCSDLSAGISGEVVHVDGGF 251 AFL S+ S I+G V V GG Sbjct: 236 VVAFLASEDSGYITGTSVEVTGGL 259 >4E6P-A nrPDB Length = 259 Score = 37.4 bits (85), Expect = 0.007, Method: Compositional matrix adjust. Identities = 70/266 (26%), Positives = 110/266 (41%), Gaps = 29/266 (10%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLG-SDI 59 M L GK L+TG A + A+ A+A REGA +A D R + AA++G + Sbjct: 3 MKRLEGKSALITGSARGIGRAF--AEAYVREGATVAIA---DIDIERARQAAAEIGPAAY 57 Query: 60 VLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFK--IAH 117 +Q DV SID A + D V++ D + +TRE ++ A Sbjct: 58 AVQMDVTRQDSIDAAIAATVEHAGGLDILVNNAAL-----FDLAPIVEITRESYEKLFAI 112 Query: 118 DISSYSFVAMAKACRSMLNPGSA--LLTLSYLGAERAIPNYNVMGLAKASLEANVRYMAN 175 +++ F A A R M+ G ++ ++ R + KA++ + + Sbjct: 113 NVAGTLFTLQA-AARQMIAQGRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAGL 171 Query: 176 AMGPEGVRVNAISAGPIRTLAASGI-----------KDFRKMLAHCEAVTPIRRTVTIED 224 + + VNAI+ G + G+ + +K L EAV P R T ED Sbjct: 172 DLIKHRINVNAIAPGVVDGEHWDGVDALFARYENRPRGEKKRLV-GEAV-PFGRMGTAED 229 Query: 225 VGNSAAFLCSDLSAGISGEVVHVDGG 250 + A FL S S I + +VDGG Sbjct: 230 LTGMAIFLASAESDYIVSQTYNVDGG 255 >3V2H-A nrPDB Length = 281 Score = 37.0 bits (84), Expect = 0.008, Method: Compositional matrix adjust. Identities = 64/261 (24%), Positives = 113/261 (43%), Gaps = 22/261 (8%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTY--QNDKLKGRVEEFAAQLGSDIVLQ-- 62 K ++TG S + +A IA+ + + GA + D+++ +E A L S VL Sbjct: 26 KTAVITGSTSGIGLA--IARTLAKAGANIVLNGFGAPDEIRTVTDEVAG-LSSGTVLHHP 82 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSY 122 D+ + + I M A + + D V++ G ++++ V R IA ++SS Sbjct: 83 ADMTKPSEIADMMAMVADRFGGADILVNNAGVQFVEKIEDFPVEQWDR---IIAVNLSS- 138 Query: 123 SFVAMAKACRSMLNPGSA-LLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 SF + A M G ++ ++ A P + AK + + +A + G Sbjct: 139 SFHTIRGAIPPMKKKGWGRIINIASAHGLVASPFKSAYVAAKHGIMGLTKTVALEVAESG 198 Query: 182 VRVNAISAGPIRT-LAASGIKDFRKMLAHCEAVT---------PIRRTVTIEDVGNSAAF 231 V VN+I G + T L I D + E P ++ +T+E V + A + Sbjct: 199 VTVNSICPGYVLTPLVEKQIPDQARTRGITEEQVINEVMLKGQPTKKFITVEQVASLALY 258 Query: 232 LCSDLSAGISGEVVHVDGGFS 252 L D +A I+G V +DGG++ Sbjct: 259 LAGDDAAQITGTHVSMDGGWT 279 >3LYL-A nrPDB Length = 247 Score = 37.0 bits (84), Expect = 0.009, Method: Compositional matrix adjust. Identities = 56/254 (22%), Positives = 109/254 (42%), Gaps = 12/254 (4%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV-LQ 62 L+ K LVTG + I + +A A+ +GA + T + + E + G L Sbjct: 3 LNEKVALVTGASR--GIGFEVAHALASKGATVVGTATSQASAEKFENSMKEKGFKARGLV 60 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSY 122 ++++ SI FAE+ D V++ G D L + ++ + ++ + + Sbjct: 61 LNISDIESIQNFFAEIKAENLAIDILVNNAGITR-DNL----MMRMSEDEWQSVINTNLS 115 Query: 123 SFVAMAKAC-RSMLNP-GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 S M+K C R M+ ++++ + P AKA + + +A + Sbjct: 116 SIFRMSKECVRGMMKKRWGRIISIGSVVGSAGNPGQTNYCAAKAGVIGFSKSLAYEVASR 175 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 + VN ++ G I T + D +K + P + +D+ + AFL S+ + I Sbjct: 176 NITVNVVAPGFIATDMTDKLTDEQKSFIATK--IPSGQIGEPKDIAAAVAFLASEEAKYI 233 Query: 241 SGEVVHVDGGFSIA 254 +G+ +HV+GG +A Sbjct: 234 TGQTLHVNGGMYMA 247 >3T7C-A nrPDB Length = 299 Score = 36.2 bits (82), Expect = 0.014, Method: Compositional matrix adjust. Identities = 35/128 (27%), Positives = 55/128 (42%), Gaps = 17/128 (13%) Query: 138 GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRT--- 194 G +++ S +G R N +K L +R MA +GP +RVN + + T Sbjct: 170 GGSIVFTSSIGGLRGAENIGNYIASKHGLHGLMRTMALELGPRNIRVNIVCPSSVATPML 229 Query: 195 ------------LAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISG 242 L ++DF ++ + V PI V D+ N+ FL SD + I+G Sbjct: 230 LNEPTYRMFRPDLENPTVEDF-QVASRQMHVLPI-PYVEPADISNAILFLVSDDARYITG 287 Query: 243 EVVHVDGG 250 + VDGG Sbjct: 288 VSLPVDGG 295 >1UZM-A nrPDB Length = 247 Score = 36.2 bits (82), Expect = 0.015, Method: Compositional matrix adjust. Identities = 59/255 (23%), Positives = 107/255 (41%), Gaps = 26/255 (10%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKL-KGRVEEFAAQLGSDIVL 61 F+S + +LVTG I IAQ + +G ++A T++ KG + Sbjct: 13 FVS-RSVLVTG--GNRGIGLAIAQRLAADGHKVAVTHRGSGAPKGLFG-----------V 58 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGD-YVNAVTREGF-KIAHDI 119 + DV + ++D F + + + V + G L D ++ +T E F K+ + Sbjct: 59 EVDVTDSDAVDRAFTAVEEHQGPVEVLVSNAG------LSADAFLMRMTEEKFEKVINAN 112 Query: 120 SSYSFVAMAKACRSML-NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMG 178 + +F +A RSM N ++ + + I N +KA + R +A + Sbjct: 113 LTGAFRVAQRASRSMQRNKFGRMIFIGSVSGLWGIGNQANYAASKAGVIGMARSIARELS 172 Query: 179 PEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSA 238 V N ++ G I T + + ++ P +R T +V +FL S+ ++ Sbjct: 173 KANVTANVVAPGYIDTDMTRALDE--RIQQGALQFIPAKRVGTPAEVAGVVSFLASEDAS 230 Query: 239 GISGEVVHVDGGFSI 253 ISG V+ VDGG + Sbjct: 231 YISGAVIPVDGGMGM 245 >4RZH-A nrPDB Length = 247 Score = 35.8 bits (81), Expect = 0.017, Method: Compositional matrix adjust. Identities = 49/221 (22%), Positives = 83/221 (37%), Gaps = 41/221 (18%) Query: 48 VEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNA 107 V E A G I +Q +VA +D + + + D V++ G Sbjct: 48 VAEIIANGGEAIAVQANVANADEVDQLIKTTLDKFSRIDVLVNNAG-------------- 93 Query: 108 VTREGFKIAHDISSYS----------FVAMAKACRSMLNPGSA-LLTLSYLGAERAIPNY 156 +TR+ + + + F+ + ML S ++ ++ + P Sbjct: 94 ITRDTLLLRMKLEDWQAVIDLNLTGVFLCTKAVSKLMLKQKSGRIINITSVAGMMGNPGQ 153 Query: 157 NVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRT-----LAASGIKDFRKMLAHCE 211 AKA + + +A + GV VNA++ G I T L A I F Sbjct: 154 ANYSAAKAGVIGFTKTVAKELASRGVTVNAVAPGFIATDMTENLNAEPILQF-------- 205 Query: 212 AVTPIRRTVTIEDVGNSAAFLCSDLSAG-ISGEVVHVDGGF 251 P+ R E+V + FL +D +A I+G+ +VDGG Sbjct: 206 --IPLARYGQPEEVAGTIRFLATDPAAAYITGQTFNVDGGM 244 >3V8B-A nrPDB Length = 283 Score = 35.8 bits (81), Expect = 0.018, Method: Compositional matrix adjust. Identities = 60/233 (25%), Positives = 92/233 (39%), Gaps = 39/233 (16%) Query: 43 KLKGRVEEFAAQL----GSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIG----F 94 + + VEE A ++ G I L+ DV+++ + +L + D V + G + Sbjct: 60 RTRTEVEEVADEIVGAGGQAIALEADVSDELQMRNAVRDLVLKFGHLDIVVANAGINGVW 119 Query: 95 APGDQL---DGDYVNAVTREG-FKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAE 150 AP D L + D AV G F H Y G A++ +S + Sbjct: 120 APIDDLKPFEWDETIAVNLRGTFLTLHLTVPYL----------KQRGGGAIVVVSSINGT 169 Query: 151 RAI--PNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLA 208 R P KA+ A V+ +A +G +RVNA+ G I T I D K+ Sbjct: 170 RTFTTPGATAYTATKAAQVAIVQQLALELGKHHIRVNAVCPGAIET----NISDNTKLRH 225 Query: 209 HCEAVTPI---RRTVTI--------EDVGNSAAFLCSDLSAGISGEVVHVDGG 250 E P+ + V I EDV FL S+ + ++G V +DGG Sbjct: 226 EEETAIPVEWPKGQVPITDGQPGRSEDVAELIRFLVSERARHVTGSPVWIDGG 278 >4RZI-B nrPDB Length = 240 Score = 35.8 bits (81), Expect = 0.021, Method: Compositional matrix adjust. Identities = 30/94 (31%), Positives = 47/94 (50%), Gaps = 13/94 (13%) Query: 158 VMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIK-DFRKMLAHCEAVTPI 216 V+G+ K+ RY GVR NA++ G I T I+ D R+ + P Sbjct: 154 VIGMMKSLAREGARY--------GVRANAVAPGFIDTEMTLAIREDIREKITKE---IPF 202 Query: 217 RRTVTIEDVGNSAAFLCSDL-SAGISGEVVHVDG 249 RR E++ + AFL S + S+ ++GEV+ V+G Sbjct: 203 RRFGKPEEIAWAVAFLLSPVASSYVTGEVLRVNG 236 >4CR6-A nrPDB Length = 271 Score = 35.4 bits (80), Expect = 0.024, Method: Compositional matrix adjust. Identities = 32/137 (23%), Positives = 57/137 (41%), Gaps = 7/137 (5%) Query: 123 SFVAMAKACRSMLNPGSA-------LLTLSYLGAERAIPNYNVMGLAKASLEANVRYMAN 175 +F+ R+M+ G+ ++T+ + + A P AK + R MA Sbjct: 123 TFLTCRAGARAMVAAGAGKDGRSARIITIGSVNSFMAEPEAAAYVAAKGGVAMLTRAMAV 182 Query: 176 AMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSD 235 + G+ VN I+ GP+ + ++ + R E+V +A FL D Sbjct: 183 DLARHGILVNMIAPGPVDVTGNNTGYSEPRLAEQVLDEVALGRPGLPEEVATAAVFLAED 242 Query: 236 LSAGISGEVVHVDGGFS 252 S+ I+G + +DGG S Sbjct: 243 GSSFITGSTITIDGGLS 259 >3VZS-A nrPDB Length = 257 Score = 35.4 bits (80), Expect = 0.028, Method: Compositional matrix adjust. Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 5/97 (5%) Query: 155 NYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVT 214 NY+ AKA L +A + +GV VN +S G I T I+ + +L A Sbjct: 163 NYST---AKAGLHGFTMALAQEVATKGVTVNTVSPGYIATDMVKAIR--QDVLDKIVATI 217 Query: 215 PIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGF 251 P++R E++ + A+L S+ S +G ++GG Sbjct: 218 PVKRLGLPEEIASICAWLSSEESGFSTGADFSLNGGL 254 >1NFF-A nrPDB Length = 260 Score = 34.3 bits (77), Expect = 0.053, Method: Compositional matrix adjust. Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 15/96 (15%) Query: 155 NYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVT 214 + V GL K++ A +GP G+RVN+I G ++T + + A A Sbjct: 157 KFAVRGLTKST--------ALELGPSGIRVNSIHPGLVKTPMTDWVPEDIFQTALGRAAE 208 Query: 215 PIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGG 250 P+ +V N +L SD S+ +G VDGG Sbjct: 209 PV-------EVSNLVVYLASDESSYSTGAEFVVDGG 237 >6ACF-A nrPDB Length = 367 Score = 34.3 bits (77), Expect = 0.060, Method: Compositional matrix adjust. Identities = 25/66 (37%), Positives = 38/66 (57%), Gaps = 7/66 (10%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGR-VEEFAAQL--GSDIV 60 L GK + V GV + +AY + + +H EGA+L T N + R VEEF A+ +DI Sbjct: 171 LEGKVVAVQGVGN---VAYHLCRHLHEEGAKLIVTDINKEAVARAVEEFGAKAVDPNDIY 227 Query: 61 -LQCDV 65 ++CD+ Sbjct: 228 GVECDI 233 >2GDZ-A nrPDB Length = 267 Score = 33.9 bits (76), Expect = 0.064, Method: Compositional matrix adjust. Identities = 52/229 (22%), Positives = 94/229 (41%), Gaps = 27/229 (11%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRV-------EEFAAQL 55 ++GK LVTG A + A+ A+A+ +GA++A N L+ V E+F Q Sbjct: 4 MVNGKVALVTGAAQGIGRAF--AEALLLKGAKVALVDWN--LEAGVQCKAALHEQFEPQ- 58 Query: 56 GSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDY-VNAVTREGFK 114 + +QCDVA+ + F ++ + + D V++ G + +N V+ Sbjct: 59 -KTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVS----- 112 Query: 115 IAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVR--- 171 + S +++ + + G ++ +S L + V +K + R Sbjct: 113 ----VISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAA 168 Query: 172 YMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTV 220 AN M GVR+NAI G + T I+ M + E I+ + Sbjct: 169 LAANLMN-SGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMI 216 >2HSD-A nrPDB Length = 253 Score = 33.9 bits (76), Expect = 0.077, Method: Compositional matrix adjust. Identities = 58/254 (22%), Positives = 105/254 (41%), Gaps = 19/254 (7%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQ- 62 LSGK +++TG A L LA D L A +LG Q Sbjct: 3 LSGKTVIITGGARGLGAEAARQAVAAGARVVLA-----DVLDEEGAATARELGDAARYQH 57 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS-S 121 DV + + A + + DG V++ G + G L+ + V E F+ +I+ + Sbjct: 58 LDVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESV-----ERFRKVVEINLT 112 Query: 122 YSFVAMAKACRSMLNPGS-ALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 F+ M +M + G +++ +S + + G +K + + A +G + Sbjct: 113 GVFIGMKTVIPAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTD 172 Query: 181 GVRVNAISAGPIRT--LAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSA 238 +RVN++ G T A +GI+ + TP+ R ++ + L SD S+ Sbjct: 173 RIRVNSVHPGMTYTPMTAETGIRQGEGNYPN----TPMGRVGEPGEIAGAVVKLLSDTSS 228 Query: 239 GISGEVVHVDGGFS 252 ++G + VDGG++ Sbjct: 229 YVTGAELAVDGGWT 242 >4KMS-A nrPDB Length = 249 Score = 33.5 bits (75), Expect = 0.085, Method: Compositional matrix adjust. Identities = 23/92 (25%), Positives = 44/92 (47%), Gaps = 2/92 (2%) Query: 162 AKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVT 221 AKA + + +A + + VN I+ G I T + + +LA P +R Sbjct: 159 AKAGIIGFTKALARETASKNITVNCIAPGYIATEMVGAVPE--DVLAKIINSIPKKRLGQ 216 Query: 222 IEDVGNSAAFLCSDLSAGISGEVVHVDGGFSI 253 E++ + AFL + + I+GE + ++GG ++ Sbjct: 217 PEEIARAVAFLVDENAGFITGETISINGGHNM 248 >3PPI-A nrPDB Length = 281 Score = 32.3 bits (72), Expect = 0.20, Method: Compositional matrix adjust. Identities = 34/113 (30%), Positives = 55/113 (48%), Gaps = 6/113 (5%) Query: 138 GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAA 197 G+ +LT S G E I AKA + A + G+RVN I+ G ++T Sbjct: 167 GALVLTASIAGYEGQI-GQTAYAAAKAGVIGLTIAAARDLSSAGIRVNTIAPGTMKTPIM 225 Query: 198 SGIKDFRKMLAHCEAVTPI-RRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDG 249 + + + LA A P +R T ++ ++AAFL ++ I+GEV+ +DG Sbjct: 226 ESVGE--EALAKFAANIPFPKRLGTPDEFADAAAFLLTN--GYINGEVMRLDG 274 >2DKN-A nrPDB Length = 255 Score = 31.6 bits (70), Expect = 0.39, Method: Compositional matrix adjust. Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Query: 180 EGVRVNAISAGPIRT-LAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSA 238 GVR+N ++ G + T L + D R + V P+ R +V + AFL ++ Sbjct: 174 RGVRLNVVAPGAVETPLLQASKADPRYGESTRRFVAPLGRGSEPREVAEAIAFLLGPQAS 233 Query: 239 GISGEVVHVDGGF 251 I G V+ VDGG Sbjct: 234 FIHGSVLFVDGGM 246 >5VT6-A nrPDB Length = 269 Score = 31.2 bits (69), Expect = 0.42, Method: Compositional matrix adjust. Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 1/93 (1%) Query: 162 AKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVT 221 AKA + + +A G+ VN +S G + T + + A P+ R Sbjct: 178 AKAGIHGFTKTLALETAKRGITVNTVSPGYLATAMVEAVPQ-DVLEAKILPQIPVGRLGR 236 Query: 222 IEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIA 254 ++V AFLCSD + ++G + ++GG ++ Sbjct: 237 PDEVAALIAFLCSDDAGFVTGADLAINGGMHMS 269 >4K6F-A nrPDB Length = 255 Score = 31.2 bits (69), Expect = 0.51, Method: Compositional matrix adjust. Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 7/92 (7%) Query: 162 AKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGI-KDF--RKMLAHCEAVTPIRR 218 AKA + + +A + +GV VN +S G + T + I +D K+L P R Sbjct: 164 AKAGMHGFTKSLALEIARKGVTVNTVSPGYLATKMVTAIPQDILDTKILPQI----PAGR 219 Query: 219 TVTIEDVGNSAAFLCSDLSAGISGEVVHVDGG 250 E+V A+LCS+ + ++G + ++GG Sbjct: 220 LGKPEEVAALVAYLCSEEAGFVTGSNIAINGG 251 >6F4A-B nrPDB Length = 644 Score = 30.8 bits (68), Expect = 0.62, Method: Compositional matrix adjust. Identities = 17/73 (23%), Positives = 39/73 (53%), Gaps = 6/73 (8%) Query: 189 AGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVD 248 AGP+R LA + F+ C +T ++++GN A +L++G + E++ ++ Sbjct: 189 AGPLRLLAREVYEKFKHENVRCNLLTGEEVIKDLDEMGNEA-----NLTSG-TIEMIPLN 242 Query: 249 GGFSIAAMNELEL 261 F + ++E+++ Sbjct: 243 QNFDVVVLDEIQM 255 >3VPX-A nrPDB Length = 364 Score = 30.4 bits (67), Expect = 0.78, Method: Compositional matrix adjust. Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 4/51 (7%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGR-VEEFAA 53 L+GK + V GV + +AY + + +H EGA+L T N++ R V+ F A Sbjct: 171 LAGKTVAVQGVGN---VAYALCEYLHEEGAKLIITDINEEAVQRAVDAFGA 218 >1GEG-A nrPDB Length = 256 Score = 30.0 bits (66), Expect = 1.1, Method: Compositional matrix adjust. Identities = 55/259 (21%), Positives = 99/259 (38%), Gaps = 22/259 (8%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKL-KGRVEEFAAQLGSDIVLQCDV 65 K LVTG I IA + ++G +A ND K E G + ++ DV Sbjct: 3 KVALVTGAGQ--GIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDV 60 Query: 66 AEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS---- 121 ++ + + K FD V++ G AP ++ ++T E ++I+ Sbjct: 61 SDRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIE-----SITPEIVDKVYNINVKGVI 115 Query: 122 YSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 + A +A + + G + S G P V +K ++ + A + P G Sbjct: 116 WGIQAAVEAFKKEGHGGKIINACSQAG-HVGNPELAVYSSSKFAVRGLTQTAARDLAPLG 174 Query: 182 VRVNAISAGPIRT---------LAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFL 232 + VN G ++T ++ + K A + R EDV ++L Sbjct: 175 ITVNGYCPGIVKTPMWAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAACVSYL 234 Query: 233 CSDLSAGISGEVVHVDGGF 251 S S ++G+ + +DGG Sbjct: 235 ASPDSDYMTGQSLLIDGGM 253 >3U4C-A nrPDB Length = 281 Score = 30.0 bits (66), Expect = 1.1, Method: Compositional matrix adjust. Identities = 41/207 (19%), Positives = 86/207 (41%), Gaps = 20/207 (9%) Query: 57 SDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSI-GFAPGDQLDGDYVNAVTREGFKI 115 S IVL D+++ + +F ++ + D +++I G AP D + E Sbjct: 75 SVIVLAGDMSDQHTRAGIFQKIESQCGRLDVLINNIPGGAP------DTFDNCNIEDMTA 128 Query: 116 AHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVM--GLAKASLEANVRYM 173 + +++ K S++ ++ +G P N+ + A+L + + Sbjct: 129 TFTQKTVAYIDAIKRASSLMKQNEFGRIINIVGNLWKEPGANMFTNSMMNAALINASKNI 188 Query: 174 ANAMGPEGVRVNAISAGPIRT----------LAASGIKDFRKMLAHCEAVTPIRRTVTIE 223 + + P + VN ++ G I T + + I +K + P++R + E Sbjct: 189 SIQLAPHNITVNCLNPGFIATDRYHQFVENVMKKNSISK-QKAEEQIASGIPMKRVGSAE 247 Query: 224 DVGNSAAFLCSDLSAGISGEVVHVDGG 250 + AAFL S+ ++ I+G+ + DGG Sbjct: 248 ETAALAAFLASEEASYITGQQISADGG 274 >3UVE-A nrPDB Length = 286 Score = 30.0 bits (66), Expect = 1.1, Method: Compositional matrix adjust. Identities = 47/199 (23%), Positives = 81/199 (40%), Gaps = 26/199 (13%) Query: 69 ASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMA 128 A++D+ +LG+ D V + G G GD ++ + E + DI+ Sbjct: 93 AAVDSGVEQLGR----LDIIVANAGIGNG----GDTLDKTSEEDWTEMIDINLAGVWKTV 144 Query: 129 KACRSML---NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVN 185 KA + G +++ S +G +A P+ AK + +R +G +RVN Sbjct: 145 KAGVPHMIAGGRGGSIILTSSVGGLKAYPHTGHYVAAKHGVVGLMRAFGVELGQHMIRVN 204 Query: 186 AISAGPIRT--LAASG-IKDFRKMLAH---------CEA--VTPIRRTVTIEDVGNSAAF 231 ++ ++T L G K FR L + C+ PI I D+ N+ F Sbjct: 205 SVHPTHVKTPMLHNEGTFKMFRPDLENPGPDDMAPICQMFHTLPIPWVEPI-DISNAVLF 263 Query: 232 LCSDLSAGISGEVVHVDGG 250 SD + I+G + +D G Sbjct: 264 FASDEARYITGVTLPIDAG 282 >3WYE-A nrPDB Length = 256 Score = 29.6 bits (65), Expect = 1.2, Method: Compositional matrix adjust. Identities = 56/257 (21%), Positives = 97/257 (37%), Gaps = 20/257 (7%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKL-KGRVEEFAAQLGSDIVLQCDV 65 K LVTG I IA + ++G +A ND K E G + ++ DV Sbjct: 3 KVALVTGAGQ--GIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDV 60 Query: 66 AEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS-F 124 ++ + + K FD V++ G A L VT E K + ++ +S F Sbjct: 61 SDRDQVFAAVEQARKTLGGFDVIVNNAGIAQIKPL-----LEVTEEDLKQIYSVNVFSVF 115 Query: 125 VAMAKACRSMLNPGSA--LLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGV 182 + A + G ++ + + A + P + K ++ + A + P G+ Sbjct: 116 FGIQAAVEAFKKEGHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAARDLAPLGI 175 Query: 183 RVNAISAGPIRT---------LAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLC 233 VN G + T L+ K + + + R EDV +FL Sbjct: 176 TVNGYCPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLA 235 Query: 234 SDLSAGISGEVVHVDGG 250 S S ++G+ + +DGG Sbjct: 236 SPDSDYMTGQSLLIDGG 252 >4DBZ-A nrPDB Length = 281 Score = 28.9 bits (63), Expect = 2.2, Method: Compositional matrix adjust. Identities = 46/259 (17%), Positives = 103/259 (39%), Gaps = 27/259 (10%) Query: 10 LVTGVASKLSIAYGIAQAMHREGAELAFTYQNDK-LKGRVEEFAAQLGSDIVLQCDVAED 68 LVTG S + + IA+ + +EG + + ++ L+ ++E CDV Sbjct: 30 LVTGATSGIGLE--IARRLGKEGLRVFVCARGEEGLRTTLKELREAGVEADGRTCDVRSV 87 Query: 69 ASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMA 128 I+ + A + + + D V++ G PG + + ++ D+ + + Sbjct: 88 PEIEALVAAVVERYGPVDVLVNNAG-RPGGGATAELAD-------ELWLDVVETNLTGVF 139 Query: 129 KACRSMLNPGSAL-------LTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 + + +L G L + ++ G ++ + + +K + + + + G Sbjct: 140 RVTKQVLKAGGMLERGTGRIVNIASTGGKQGLVHAAPYSASKHGVVGFTKALGLELARTG 199 Query: 182 VRVNAISAGPIRTLAASGIKDF---------RKMLAHCEAVTPIRRTVTIEDVGNSAAFL 232 + VNA+ G + T A+ +++ + A PI R V +V A+L Sbjct: 200 ITVNAVCPGFVETPMAASVREHYSDIWEVSTEEAFDRITARVPIGRYVQPSEVAEMVAYL 259 Query: 233 CSDLSAGISGEVVHVDGGF 251 +A ++ + ++V GG Sbjct: 260 IGPGAAAVTAQALNVCGGL 278 >5O3Z-A nrPDB Length = 263 Score = 28.9 bits (63), Expect = 2.4, Method: Compositional matrix adjust. Identities = 13/36 (36%), Positives = 21/36 (58%) Query: 215 PIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGG 250 P++R +DV N F SD +A +G+ ++V GG Sbjct: 224 PLKRGCDYQDVLNVLLFYASDKAAYCTGQSINVTGG 259 >2HYP-A nrPDB Length = 280 Score = 28.9 bits (63), Expect = 2.6, Method: Compositional matrix adjust. Identities = 12/18 (66%), Positives = 16/18 (88%) Query: 43 KLKGRVEEFAAQLGSDIV 60 KL+G VE FAAQLG+++V Sbjct: 77 KLRGLVEPFAAQLGAELV 94 >3IB8-A nrPDB Length = 330 Score = 28.9 bits (63), Expect = 2.6, Method: Compositional matrix adjust. Identities = 12/18 (66%), Positives = 16/18 (88%) Query: 43 KLKGRVEEFAAQLGSDIV 60 KL+G VE FAAQLG+++V Sbjct: 87 KLRGLVEPFAAQLGAELV 104 >3WTC-A nrPDB Length = 262 Score = 28.5 bits (62), Expect = 3.4, Method: Compositional matrix adjust. Identities = 57/259 (22%), Positives = 95/259 (36%), Gaps = 16/259 (6%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAE-LAFTYQNDKLKGRVEEFAAQLGSDIVLQ 62 LSGK VTG A I IA + ++GA+ + + D L +E A + L Sbjct: 6 LSGKIAAVTGAAQ--GIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEALGRRAVALT 63 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSY 122 D++ + A+ K D V++ G + D A + F I + Sbjct: 64 ADISNRDQFRSTLADAAKTLGGLDIMVNNAGICQVKPIL-DIEPAEIEKIFSINVQGVLW 122 Query: 123 SFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGV 182 A A + G + S G E P K ++ A + A + G+ Sbjct: 123 GMQAAATLFKEKGTKGKIINACSIAGHE-GYPLLGAYSATKFAVRALTQSAAKELASSGI 181 Query: 183 RVNAISAGPI----------RTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFL 232 VN+ G + R +G + + E + + R T +DV A+L Sbjct: 182 TVNSYCPGIVGTDMWVTIDKRMAEITGTEIGATYKKYVEGI-ALGRVETADDVAGFVAYL 240 Query: 233 CSDLSAGISGEVVHVDGGF 251 S + ++G+ V +DGG Sbjct: 241 SSSDADYMTGQSVLIDGGL 259 >3MKQ-B nrPDB Length = 177 Score = 28.1 bits (61), Expect = 4.3, Method: Compositional matrix adjust. Identities = 18/43 (41%), Positives = 22/43 (51%) Query: 10 LVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFA 52 LVTG +KLS IAQ G+ L T+ N+ K R FA Sbjct: 71 LVTGDVNKLSKMQNIAQTREDFGSMLLNTFYNNSTKERSSIFA 113 >2R8K-A nrPDB Length = 554 Score = 27.7 bits (60), Expect = 5.1, Method: Compositional matrix adjust. Identities = 10/19 (52%), Positives = 15/19 (78%) Query: 63 CDVAEDASIDTMFAELGKV 81 CD+ E ASID +F +LG++ Sbjct: 169 CDLVERASIDEVFLDLGRI 187 >4CEX-C nrPDB Length = 570 Score = 27.7 bits (60), Expect = 5.6, Method: Compositional matrix adjust. Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 11/81 (13%) Query: 178 GP-EGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDL 236 GP EG + ++ GP + KML E + PI + + G+S A + + Sbjct: 163 GPAEGSKATTVTPGPW---------NIEKMLKSTEGL-PINVGILGKGHGSSIAPIMEQI 212 Query: 237 SAGISGEVVHVDGGFSIAAMN 257 AG +G +H D G + A+++ Sbjct: 213 DAGAAGLKIHEDWGATPASID 233 >2CFC-A nrPDB Length = 250 Score = 27.3 bits (59), Expect = 6.2, Method: Compositional matrix adjust. Identities = 32/192 (16%), Positives = 76/192 (39%) Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 ++ DVA++ ++ A + + D V++ G + + V + +A ++ Sbjct: 57 VRADVADEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVR 116 Query: 121 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 A +L ++ ++ + + A P + +K ++ + +A Sbjct: 117 GIFLGCRAVLPHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDYAGS 176 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 G+R NA+ G I T D ++ A P + T V ++ FL + + + Sbjct: 177 GIRCNAVCPGMIETPMTQWRLDQPELRDQVLARIPQKEIGTAAQVADAVMFLAGEDATYV 236 Query: 241 SGEVVHVDGGFS 252 +G + +DG ++ Sbjct: 237 NGAALVMDGAYT 248 >4DRY-A nrPDB Length = 281 Score = 27.3 bits (59), Expect = 7.2, Method: Compositional matrix adjust. Identities = 19/72 (26%), Positives = 34/72 (47%), Gaps = 2/72 (2%) Query: 24 IAQAMHREGAELAFT-YQNDKLKGRVEEFAAQLGSDI-VLQCDVAEDASIDTMFAELGKV 81 IAQA+ EG + T + D L E + G+ + + CDV + + +FA + Sbjct: 49 IAQALSAEGYSVVITGRRPDVLDAAAGEIGGRTGNIVRAVVCDVGDPDQVAALFAAVRAE 108 Query: 82 WPKFDGFVHSIG 93 + + D V++ G Sbjct: 109 FARLDLLVNNAG 120 >2H92-A nrPDB Length = 219 Score = 26.9 bits (58), Expect = 8.5, Method: Compositional matrix adjust. Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 9/63 (14%) Query: 5 SGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAA---QLGSDIVL 61 +GK + VAS+LS+ Y AM+R A TY+ KL + E+FA Q D+ Sbjct: 14 AGKSTIAKRVASELSMIYVDTGAMYR-----ALTYKYLKL-NKTEDFAKLVDQTTLDLTY 67 Query: 62 QCD 64 + D Sbjct: 68 KAD 70 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5CFZ-A nrPDB 345 1e-95 4JQC-A nrPDB 343 5e-95 4ZJU-A nrPDB 302 1e-82 4NR0-A nrPDB 298 2e-81 5KOI-A nrPDB 294 2e-80 2P91-A nrPDB 294 3e-80 4M89-A nrPDB 290 5e-79 5TF4-A nrPDB 289 6e-79 5I9N-A nrPDB 289 9e-79 3GRK-A nrPDB 287 3e-78 4J3F-A nrPDB 279 8e-76 3K2E-A nrPDB 279 1e-75 3OIG-A nrPDB 273 7e-74 5YCX-A nrPDB 270 4e-73 2YW9-A nrPDB 267 4e-72 4NK4-A nrPDB 266 8e-72 2PD3-A nrPDB 259 8e-70 4ALL-A nrPDB 245 1e-65 2PNF-A nrPDB 237 3e-63 3OSU-A nrPDB 233 4e-62 2HQ1-A nrPDB 230 3e-61 2UVD-A nrPDB 230 6e-61 4JRO-A nrPDB 227 4e-60 3RSH-A nrPDB 226 7e-60 3O4R-A nrPDB 225 2e-59 2ZAT-A nrPDB 220 3e-58 3WOH-A nrPDB 220 4e-58 3EMK-A nrPDB 220 4e-58 4M8S-A nrPDB 217 4e-57 1Q7C-A nrPDB 216 6e-57 5CDY-A nrPDB 215 1e-56 2EW8-A nrPDB 215 2e-56 3OIC-A nrPDB 213 4e-56 3R3S-A nrPDB 213 5e-56 2C07-A nrPDB 212 1e-55 3GRP-A nrPDB 211 2e-55 3FTP-A nrPDB 211 3e-55 1GEE-A nrPDB 209 8e-55 3F9I-A nrPDB 209 9e-55 5ITV-A nrPDB 208 1e-54 4DMM-A nrPDB 208 2e-54 6NRP-A nrPDB 208 2e-54 2NM0-A nrPDB 207 3e-54 3AUT-A nrPDB 207 4e-54 1AE1-A nrPDB 206 8e-54 4BO1-A nrPDB 205 1e-53 4MOW-A nrPDB 205 2e-53 1YXM-A nrPDB 203 4e-53 2PH3-A nrPDB 203 6e-53 2Q2Q-A nrPDB 202 1e-52 5U9P-A nrPDB 202 1e-52 4NBV-A nrPDB 201 3e-52 6CI9-A nrPDB 200 4e-52 5T5Q-A nrPDB 199 9e-52 1DOH-A nrPDB 199 1e-51 4IIN-A nrPDB 199 1e-51 4IIV-A nrPDB 199 1e-51 2AE2-A nrPDB 198 2e-51 5OVL-A nrPDB 196 6e-51 3V2G-A nrPDB 196 6e-51 1AHH-A nrPDB 196 6e-51 4Q9N-A nrPDB 194 3e-50 4Z9Y-A nrPDB 194 4e-50 3EZL-A nrPDB 192 1e-49 3U5T-A nrPDB 192 1e-49 5OVJ-A nrPDB 192 2e-49 3OEC-A nrPDB 191 4e-49 2NTV-A nrPDB 190 4e-49 5YSS-A nrPDB 189 1e-48 3UF0-A nrPDB 189 1e-48 1K2W-A nrPDB 188 2e-48 3D3W-A nrPDB 188 2e-48 1ENP-A nrPDB 188 2e-48 2O2S-A nrPDB 188 2e-48 1O5I-A nrPDB 187 4e-48 4OYR-A nrPDB 187 5e-48 5OJG-A nrPDB 186 6e-48 1HXH-A nrPDB 186 8e-48 3A28-C nrPDB 185 1e-47 4AVY-A nrPDB 185 2e-47 5JY1-A nrPDB 180 6e-46 4HP8-A nrPDB 178 2e-45 1X1T-A nrPDB 178 2e-45 4IS3-A nrPDB 178 2e-45 2AG5-A nrPDB 178 3e-45 4FC7-A nrPDB 177 4e-45 5JS6-A nrPDB 177 5e-45 4GKB-A nrPDB 176 6e-45 5B1Y-A nrPDB 176 7e-45 2X9N-A nrPDB 176 7e-45 1CYD-A nrPDB 173 6e-44 1P33-A nrPDB 173 6e-44 2FWM-X nrPDB 173 7e-44 4EGF-A nrPDB 171 3e-43 5EJ2-A nrPDB 170 6e-43 2QHX-A nrPDB 170 7e-43 2BFA-A nrPDB 169 1e-42 1W73-A nrPDB 168 2e-42 3UN1-A nrPDB 160 4e-40 2PTG-A nrPDB 160 5e-40 2BGM-A nrPDB 160 7e-40 1H5Q-A nrPDB 158 2e-39 3F4B-A nrPDB 156 7e-39 4DA9-A nrPDB 156 7e-39 2O2Y-A nrPDB 153 6e-38 3UCF-A nrPDB 119 1e-27 1FJH-A nrPDB 98 3e-21 Sequences not found previously or not previously below threshold: 3LYL-A nrPDB 217 4e-57 4RZH-A nrPDB 205 2e-53 4NBT-A nrPDB 194 3e-50 4K6F-A nrPDB 193 9e-50 2CDH-G nrPDB 192 1e-49 1GEG-A nrPDB 191 2e-49 4CQM-B nrPDB 190 6e-49 3WYE-A nrPDB 188 2e-48 3VZS-A nrPDB 186 8e-48 3RWB-A nrPDB 185 1e-47 1UZM-A nrPDB 185 3e-47 4KMS-A nrPDB 184 3e-47 5VT6-A nrPDB 182 1e-46 3W8F-A nrPDB 181 2e-46 4E6P-A nrPDB 181 3e-46 3V2H-A nrPDB 179 1e-45 4CQL-A nrPDB 178 2e-45 4RZI-B nrPDB 177 5e-45 2CFC-A nrPDB 176 6e-45 1NFF-A nrPDB 174 4e-44 3UVE-A nrPDB 174 4e-44 4DBZ-A nrPDB 173 5e-44 2B4Q-A nrPDB 172 1e-43 3WTC-A nrPDB 169 1e-42 3T7C-A nrPDB 167 3e-42 2HSD-A nrPDB 164 4e-41 3GDF-A nrPDB 160 5e-40 3V8B-A nrPDB 157 5e-39 3U4C-A nrPDB 156 1e-38 2GDZ-A nrPDB 146 9e-36 4TRR-A nrPDB 145 2e-35 4CR6-A nrPDB 144 4e-35 3PXX-A nrPDB 143 6e-35 3ZV3-A nrPDB 139 7e-34 5IZ4-A nrPDB 138 2e-33 1BDB-A nrPDB 136 1e-32 4RGB-A nrPDB 129 1e-30 5O3Z-A nrPDB 128 4e-30 1E3W-A nrPDB 127 4e-30 2O23-A nrPDB 123 6e-29 3OML-A nrPDB 118 3e-27 5ILO-A nrPDB 116 9e-27 4DRY-A nrPDB 114 4e-26 3PPI-A nrPDB 113 6e-26 3RKU-A nrPDB 113 6e-26 2NWQ-A nrPDB 106 9e-24 2HRB-A nrPDB 105 2e-23 3KZV-A nrPDB 104 5e-23 1A27-A nrPDB 100 1e-21 6CGE-A nrPDB 99 2e-21 3DWF-A nrPDB 98 3e-21 2DKN-A nrPDB 98 3e-21 1N5D-A nrPDB 98 3e-21 5L51-A nrPDB 95 4e-20 3E9N-A nrPDB 94 7e-20 5PGZ-A nrPDB 93 1e-19 3BHI-A nrPDB 93 2e-19 1SNY-A nrPDB 90 8e-19 3O26-A nrPDB 86 2e-17 4HBG-A nrPDB 81 4e-16 5WQO-A nrPDB 80 1e-15 5LCX-A nrPDB 78 6e-15 3U9L-A nrPDB 76 1e-14 1B15-A nrPDB 75 3e-14 1MG5-A nrPDB 73 9e-14 4Z3K-A nrPDB 72 3e-13 4HWK-A nrPDB 72 3e-13 1OAA-A nrPDB 66 1e-11 5TQV-A nrPDB 58 3e-09 3SLK-A nrPDB 57 1e-08 3ORF-A nrPDB 48 3e-06 2PK3-A nrPDB 48 4e-06 4LIS-A nrPDB 47 1e-05 3RFT-A nrPDB 46 2e-05 2Q1W-A nrPDB 44 5e-05 2GN9-A nrPDB 42 3e-04 6ACF-A nrPDB 41 4e-04 6BWL-A nrPDB 41 6e-04 5INT-A nrPDB 40 9e-04 1DIR-A nrPDB 40 0.001 1OOE-A nrPDB 39 0.002 3ENK-A nrPDB 38 0.003 3VPX-A nrPDB 37 0.009 3SC6-A nrPDB 36 0.013 4K28-A nrPDB 36 0.015 3NJ4-A nrPDB 36 0.024 3SXP-A nrPDB 35 0.029 1Z45-A nrPDB 35 0.032 2Z95-A nrPDB 34 0.054 3OND-A nrPDB 34 0.057 2YNM-D nrPDB 34 0.068 4EUF-A nrPDB 34 0.073 3DFZ-A nrPDB 34 0.078 3X2F-A nrPDB 34 0.086 1RPN-A nrPDB 33 0.11 1GPJ-A nrPDB 33 0.13 6ACQ-A nrPDB 33 0.17 3H9U-A nrPDB 33 0.17 4QQW-A nrPDB 32 0.27 3HFS-A nrPDB 32 0.32 6GAR-A nrPDB 32 0.35 1LU9-A nrPDB 31 0.37 3CT4-A nrPDB 31 0.50 1BXK-A nrPDB 31 0.50 2DFV-A nrPDB 31 0.53 4DGK-A nrPDB 31 0.57 2OWO-A nrPDB 31 0.63 4PZE-A nrPDB 31 0.75 4W5U-B nrPDB 30 0.94 6BII-A nrPDB 30 1.0 1F14-A nrPDB 30 1.1 5KIA-A nrPDB 30 1.1 6G4S-u nrPDB 30 1.3 2EER-A nrPDB 30 1.4 4MIT-A nrPDB 29 1.5 5OPT-L nrPDB 29 1.5 5K1S-A nrPDB 29 1.5 1IM2-A nrPDB 29 1.6 6AZ1-E nrPDB 29 1.6 6DEB-A nrPDB 29 1.6 1FGS-A nrPDB 29 1.8 2IY3-A nrPDB 29 1.8 2GAG-A nrPDB 29 1.8 4B3J-A nrPDB 29 2.0 3C1M-A nrPDB 29 2.0 3AOE-A nrPDB 29 2.0 3K30-A nrPDB 29 2.1 2FFH-A nrPDB 29 2.1 1ZEJ-A nrPDB 29 2.2 5M65-A nrPDB 29 2.2 3HDH-A nrPDB 29 2.3 2GGS-A nrPDB 29 2.3 4V62-AB nrPDB 29 2.3 1IZL-B nrPDB 29 2.4 1OFI-A nrPDB 29 2.4 4J2O-A nrPDB 29 2.5 2HK7-A nrPDB 29 2.5 3G1U-A nrPDB 29 2.5 4U83-A nrPDB 29 2.6 5A2X-A nrPDB 29 2.7 2AA4-A nrPDB 29 2.7 1RJ9-B nrPDB 29 2.7 4EJ6-A nrPDB 29 2.8 3AEK-B nrPDB 29 3.0 3GFB-A nrPDB 29 3.1 5VM2-A nrPDB 28 3.1 4WEQ-A nrPDB 28 3.8 2Q4B-A nrPDB 28 4.0 4V8M-A1 nrPDB 28 4.1 4NFY-A nrPDB 28 4.1 6DKH-A nrPDB 28 4.5 6GNF-A nrPDB 28 5.0 4FIO-A nrPDB 28 5.0 4GBJ-A nrPDB 28 5.1 5B4F-A nrPDB 28 5.3 3DQQ-A nrPDB 28 5.6 3FBG-A nrPDB 28 5.7 2RKB-A nrPDB 28 6.1 3LNU-A nrPDB 28 6.5 1YXY-A nrPDB 27 6.9 1SOW-A nrPDB 27 7.1 4J6F-A nrPDB 27 7.2 2RIR-A nrPDB 27 7.3 5LZL-A nrPDB 27 7.8 4N18-A nrPDB 27 8.1 4AY7-A nrPDB 27 8.2 5F5N-A nrPDB 27 8.4 2VN8-A nrPDB 27 8.5 6H5E-B nrPDB 27 8.9 1O89-A nrPDB 27 9.2 1T9K-A nrPDB 27 9.4 >5CFZ-A nrPDB Length = 305 Score = 345 bits (886), Expect = 1e-95, Method: Composition-based stats. Identities = 262/262 (100%), Positives = 262/262 (100%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 60 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV Sbjct: 44 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 103 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS Sbjct: 104 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 163 Query: 121 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE Sbjct: 164 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 223 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI Sbjct: 224 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 283 Query: 241 SGEVVHVDGGFSIAAMNELELK 262 SGEVVHVDGGFSIAAMNELELK Sbjct: 284 SGEVVHVDGGFSIAAMNELELK 305 >4JQC-A nrPDB Length = 282 Score = 343 bits (880), Expect = 5e-95, Method: Composition-based stats. Identities = 262/262 (100%), Positives = 262/262 (100%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 60 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV Sbjct: 21 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 80 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS Sbjct: 81 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 140 Query: 121 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE Sbjct: 141 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 200 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI Sbjct: 201 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 260 Query: 241 SGEVVHVDGGFSIAAMNELELK 262 SGEVVHVDGGFSIAAMNELELK Sbjct: 261 SGEVVHVDGGFSIAAMNELELK 282 >4ZJU-A nrPDB Length = 275 Score = 302 bits (773), Expect = 1e-82, Method: Composition-based stats. Identities = 169/258 (65%), Positives = 205/258 (79%), Gaps = 1/258 (0%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVL 61 G L+GKR L+ GVASKLSIAYGIAQA+HREGAELAFTY N+KLK RV+EFA Q GS +V Sbjct: 12 GLLAGKRFLIAGVASKLSIAYGIAQALHREGAELAFTYPNEKLKKRVDEFAEQFGSKLVF 71 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 CDVA DA ID FAEL K W DG VHSIGFAP LDGD+ + R+GFKIAHDIS+ Sbjct: 72 PCDVAVDAEIDNAFAELAKHWDGVDGVVHSIGFAPAHTLDGDFTDVTDRDGFKIAHDISA 131 Query: 122 YSFVAMAKACRSMLN-PGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 YSFVAMA+A + +L LLTL+Y G+ER +PNYNVMG+AKASLEA VRY+A+++G + Sbjct: 132 YSFVAMARAAKPLLQARQGCLLTLTYQGSERVMPNYNVMGMAKASLEAGVRYLASSLGVD 191 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 G+RVNAISAGPIRTLAASGIK FRKML E V P++R VTIE+VGN+A FLCS ++GI Sbjct: 192 GIRVNAISAGPIRTLAASGIKSFRKMLDANEKVAPLKRNVTIEEVGNAALFLCSPWASGI 251 Query: 241 SGEVVHVDGGFSIAAMNE 258 +GE+++VD GF+ M++ Sbjct: 252 TGEILYVDAGFNTVGMSQ 269 >4NR0-A nrPDB Length = 273 Score = 298 bits (763), Expect = 2e-81, Method: Composition-based stats. Identities = 182/263 (69%), Positives = 216/263 (82%), Gaps = 3/263 (1%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGS--D 58 MGFL+GKR L+ GVASKLSIA GIA AMHREGAELAFTYQNDKL+GRVEEFA+ GS + Sbjct: 1 MGFLTGKRALIVGVASKLSIASGIAAAMHREGAELAFTYQNDKLRGRVEEFASGWGSRPE 60 Query: 59 IVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHD 118 + CDVA+D+ I+ +FA LGK W D VHS+GFAPGDQLDGD+ TREGF+IAHD Sbjct: 61 LCFPCDVADDSQIEAVFAALGKHWDGLDIIVHSVGFAPGDQLDGDFTAVTTREGFRIAHD 120 Query: 119 ISSYSFVAMAKACRSMLN-PGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAM 177 IS+YSF+A+AKA R M+ +LLTLSYLGAER +PNYNVMG+AKASLEA VRY+A ++ Sbjct: 121 ISAYSFIALAKAGREMMKGRNGSLLTLSYLGAERTMPNYNVMGMAKASLEAGVRYLAGSL 180 Query: 178 GPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLS 237 G EG RVNA+SAGPIRTLAASGIK FRKMLA E TP+RR VTIE+VGN+ AFLCSDL+ Sbjct: 181 GAEGTRVNAVSAGPIRTLAASGIKSFRKMLAANERQTPLRRNVTIEEVGNAGAFLCSDLA 240 Query: 238 AGISGEVVHVDGGFSIAAMNELE 260 +GISGE+++VDGGF+ AM L+ Sbjct: 241 SGISGEILYVDGGFNTTAMGPLD 263 >5KOI-A nrPDB Length = 293 Score = 294 bits (754), Expect = 2e-80, Method: Composition-based stats. Identities = 132/260 (50%), Positives = 181/260 (69%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVL 61 G + GKR L+ GVA+ S+A+GIA+ + +GAELAFTYQ D L RV+ A Q+GSD VL Sbjct: 24 GLMQGKRGLIMGVANNHSLAWGIAKQLAAQGAELAFTYQGDALGKRVKPLAEQVGSDFVL 83 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 CDV + A++D +F E+ K W D VH+IGF+ +L G Y + TRE F IS+ Sbjct: 84 PCDVEDIATVDAVFEEIEKKWGGLDFLVHAIGFSDKTELKGRYADVTTRENFSRTMVISA 143 Query: 122 YSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 YSF +A+ ++ G ++LTL+Y G+ R IPNYNVMG+AKA+LEA VRY+A GP+G Sbjct: 144 YSFTEVAQRAEKLMKDGGSILTLTYGGSTRTIPNYNVMGVAKAALEAMVRYLAADYGPQG 203 Query: 182 VRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGIS 241 +RVNAISAGP+RTLA +GI D R + ++ +P+RRTV I+DVG SA +L SDLS+G++ Sbjct: 204 IRVNAISAGPVRTLAGAGIGDARAIFSYQRRNSPLRRTVDIDDVGKSAVYLLSDLSSGVT 263 Query: 242 GEVVHVDGGFSIAAMNELEL 261 GE+ VD G++I +M LE Sbjct: 264 GEIHFVDSGYNIVSMPTLEE 283 >2P91-A nrPDB Length = 285 Score = 294 bits (752), Expect = 3e-80, Method: Composition-based stats. Identities = 130/263 (49%), Positives = 178/263 (67%), Gaps = 2/263 (0%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 60 MG L GKR L+TGVA++ SIAYGIA++ HREGA+LAFTY KL+ RV E A GSD+V Sbjct: 16 MGLLEGKRALITGVANERSIAYGIAKSFHREGAQLAFTYATPKLEKRVREIAKGFGSDLV 75 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 ++CDV+ D I + L + W D VHSI +AP ++ G ++ +REGFKIA DIS Sbjct: 76 VKCDVSLDEDIKNLKKFLEENWGSLDIIVHSIAYAPKEEFKGGVID-TSREGFKIAMDIS 134 Query: 121 SYSFVAMAKACRSMLN-PGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 YS +A+ + ++ A++TLSY GAE+ +P+YNVMG+AKA+LE+ VRY+A + Sbjct: 135 VYSLIALTRELLPLMEGRNGAIVTLSYYGAEKVVPHYNVMGIAKAALESTVRYLAYDIAK 194 Query: 180 EGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAG 239 G R+NAISAGP++TLAA I F ++ H V P + +TIEDVG++A FLCSD + Sbjct: 195 HGHRINAISAGPVKTLAAYSITGFHLLMEHTTKVNPFGKPITIEDVGDTAVFLCSDWARA 254 Query: 240 ISGEVVHVDGGFSIAAMNELELK 262 I+GEVVHVD G+ I + E + Sbjct: 255 ITGEVVHVDNGYHIMGVFGREEE 277 >4M89-A nrPDB Length = 261 Score = 290 bits (742), Expect = 5e-79, Method: Composition-based stats. Identities = 157/259 (60%), Positives = 202/259 (77%), Gaps = 1/259 (0%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 60 MGFL GK+IL+TG+ S+ SIAYGIA+A +GAELAFTY DKL+ RV + AA+L S++V Sbjct: 1 MGFLQGKKILITGMISERSIAYGIAKACREQGAELAFTYVVDKLEERVRKMAAELDSELV 60 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 +CDVA D I+ +FA+LGK W DG VHSIGFAP + L GD++++++RE F AH+IS Sbjct: 61 FRCDVASDDEINQVFADLGKHWDGLDGLVHSIGFAPKEALSGDFLDSISREAFNTAHEIS 120 Query: 121 SYSFVAMAKACRSMLN-PGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 +YS A+AKA R M+ SA++ LSYLGA RAIPNYNVMG+AKASLEA +R+ A +G Sbjct: 121 AYSLPALAKAARPMMRGRNSAIVALSYLGAVRAIPNYNVMGMAKASLEAGIRFTAACLGK 180 Query: 180 EGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAG 239 EG+R N ISAGPI+TLAASGI DF K+L H A P+RR VTIE+VGN+AAFL SDLS+G Sbjct: 181 EGIRCNGISAGPIKTLAASGIADFGKLLGHVAAHNPLRRNVTIEEVGNTAAFLLSDLSSG 240 Query: 240 ISGEVVHVDGGFSIAAMNE 258 I+GE+ +VDGG+SI A++ Sbjct: 241 ITGEITYVDGGYSINALST 259 >5TF4-A nrPDB Length = 274 Score = 289 bits (741), Expect = 6e-79, Method: Composition-based stats. Identities = 130/259 (50%), Positives = 182/259 (70%), Gaps = 1/259 (0%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVL 61 G L GKR L+ G+A+ SIA+GIA+ GAELAFTYQ + +K RVE A ++ + Sbjct: 8 GLLYGKRGLILGLANNRSIAWGIAKTASSAGAELAFTYQGEAMKKRVEPLAEEVKGFVCG 67 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 CDV++ ASID +F + K W K D VH+IGF+ ++L G YV+ ++ F + +IS Sbjct: 68 HCDVSDSASIDAVFNTIEKKWGKLDFLVHAIGFSDKEELSGRYVD-ISESNFMMTMNISV 126 Query: 122 YSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 YS A+ K +++ G ++LTL+Y GAE+ +PNYNVMG+AKA+LEA+V+Y+A +GP+ Sbjct: 127 YSLTALTKRAEKLMSDGGSILTLTYYGAEKVVPNYNVMGVAKAALEASVKYLAVDLGPKH 186 Query: 182 VRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGIS 241 +RVNAISAGPI+TLAASGI DFR +L E P+RRTVTIE+VG+SA +L SDLS ++ Sbjct: 187 IRVNAISAGPIKTLAASGIGDFRYILKWNEYNAPLRRTVTIEEVGDSALYLLSDLSRSVT 246 Query: 242 GEVVHVDGGFSIAAMNELE 260 GEV HVD G++I M ++ Sbjct: 247 GEVHHVDSGYNIIGMKAVD 265 >5I9N-A nrPDB Length = 276 Score = 289 bits (740), Expect = 9e-79, Method: Composition-based stats. Identities = 165/264 (62%), Positives = 207/264 (78%), Gaps = 2/264 (0%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 60 MGFL GKRIL+TG+ S SIAYGIA+A REGAELAFTY D+ K R+ EFAA+ GS++V Sbjct: 1 MGFLDGKRILLTGLLSNRSIAYGIAKACKREGAELAFTYVGDRFKDRITEFAAEFGSELV 60 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 CDVA+DA ID +FA L W DG VHSIGFAP + + GD+++ +TRE F+IAHDIS Sbjct: 61 FPCDVADDAQIDALFASLKTHWDSLDGLVHSIGFAPREAIAGDFLDGLTRENFRIAHDIS 120 Query: 121 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 +YSF A+AKA ML+ ++LLTLSYLGAERAIPNYN MGLAKA+LEA+VRY+A ++G + Sbjct: 121 AYSFPALAKAALPMLSDDASLLTLSYLGAERAIPNYNTMGLAKAALEASVRYLAVSLGAK 180 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 GVRVNAISAGPI+TLAASGIK F K+L E+ +P++R VTIE VGN+ AFL SDL++G+ Sbjct: 181 GVRVNAISAGPIKTLAASGIKSFGKILDFVESNSPLKRNVTIEQVGNAGAFLLSDLASGV 240 Query: 241 SGEVVHVDGGFS--IAAMNELELK 262 + EV+HVD GF+ + M LE K Sbjct: 241 TAEVMHVDSGFNAVVGGMAGLEEK 264 >3GRK-A nrPDB Length = 293 Score = 287 bits (735), Expect = 3e-78, Method: Composition-based stats. Identities = 131/259 (50%), Positives = 177/259 (68%), Gaps = 1/259 (0%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVL 61 G L GKR L+ GVA+ SIA+GIA+A GAELAFTYQ D LK RVE A +LG+ + Sbjct: 27 GLLQGKRGLILGVANNRSIAWGIAKAAREAGAELAFTYQGDALKKRVEPLAEELGAFVAG 86 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 CDVA+ ASID +F L K W K D VH+IGF+ D+L G Y++ + F IS Sbjct: 87 HCDVADAASIDAVFETLEKKWGKLDFLVHAIGFSDKDELTGRYID-TSEANFTNTMLISV 145 Query: 122 YSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 YS A+++ ++ G ++LTL+Y GAE+ +PNYNVMG+AKA+LEA+V+Y+A +GP+ Sbjct: 146 YSLTAVSRRAEKLMADGGSILTLTYYGAEKVMPNYNVMGVAKAALEASVKYLAVDLGPQN 205 Query: 182 VRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGIS 241 +RVNAISAGPI+TLAASGI DFR +L E P+RRTVTI++VG+ + SDLS ++ Sbjct: 206 IRVNAISAGPIKTLAASGIGDFRYILKWNEYNAPLRRTVTIDEVGDVGLYFLSDLSRSVT 265 Query: 242 GEVVHVDGGFSIAAMNELE 260 GEV H D G+ + M ++ Sbjct: 266 GEVHHADSGYHVIGMKAVD 284 >4J3F-A nrPDB Length = 280 Score = 279 bits (714), Expect = 8e-76, Method: Composition-based stats. Identities = 152/260 (58%), Positives = 200/260 (76%), Gaps = 2/260 (0%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 60 MGFL+GK+IL+TG+ S SIAYGIA+AMHREGAELAFTY + K RVE+ A+ V Sbjct: 21 MGFLAGKKILITGLLSNKSIAYGIAKAMHREGAELAFTYVG-QFKDRVEKLCAEFNPAAV 79 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 L CDV D I +F ELGKVW D VHSI FAP DQL+G++++ VTREGF IAHDIS Sbjct: 80 LPCDVISDQEIKDLFVELGKVWDGLDAIVHSIAFAPRDQLEGNFIDCVTREGFSIAHDIS 139 Query: 121 SYSFVAMAKACRSML-NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 +YSF A+AK RSM+ N ++++ L+Y+GAE+A+P+YN MG+AKASLEA VRY A A+G Sbjct: 140 AYSFAALAKEGRSMMKNRNASMVALTYIGAEKAMPSYNTMGVAKASLEATVRYTALALGE 199 Query: 180 EGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAG 239 +G++VNA+SAGPI+TLAASGI +F+KML + V+P+++ V I +VGN+ AFLCSD++ G Sbjct: 200 DGIKVNAVSAGPIKTLAASGISNFKKMLDYNAMVSPLKKNVDIMEVGNTVAFLCSDMATG 259 Query: 240 ISGEVVHVDGGFSIAAMNEL 259 I+GEVVHVD G+ +M + Sbjct: 260 ITGEVVHVDAGYHCVSMGNV 279 >3K2E-A nrPDB Length = 296 Score = 279 bits (713), Expect = 1e-75, Method: Composition-based stats. Identities = 111/258 (43%), Positives = 170/258 (65%), Gaps = 1/258 (0%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQ 62 + GK+ ++ GVA+ S+A+GIA+A+ +GAE+A TY ++ K RV+ A LG + + Sbjct: 27 LMEGKKGVIIGVANDKSLAWGIAKAVCAQGAEVALTYLSETFKKRVDPLAESLGVKLTVP 86 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSY 122 CDV++ S+D MF L + W D VH++ F+ ++L G YV+ + F + IS Y Sbjct: 87 CDVSDAESVDNMFKVLAEEWGSLDFVVHAVAFSDKNELKGRYVD-TSLGNFLTSMHISCY 145 Query: 123 SFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGV 182 SF +A ++ G ++LTLSY GAE+ +P+YNVMG+ KA+LEA+V+Y+A +G + + Sbjct: 146 SFTYIASKAEPLMTNGGSILTLSYYGAEKVVPHYNVMGVCKAALEASVKYLAVDLGKQQI 205 Query: 183 RVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISG 242 RVNAISAGP+RTLA+SGI DF +L + +P+RR T++DVG +A +L SDL G +G Sbjct: 206 RVNAISAGPVRTLASSGISDFHYILTWNKYNSPLRRNTTLDDVGGAALYLLSDLGRGTTG 265 Query: 243 EVVHVDGGFSIAAMNELE 260 E VHVD G+ + M ++ Sbjct: 266 ETVHVDCGYHVVGMKSVD 283 >3OIG-A nrPDB Length = 266 Score = 273 bits (698), Expect = 7e-74, Method: Composition-based stats. Identities = 133/258 (51%), Positives = 178/258 (68%), Gaps = 4/258 (1%) Query: 1 MGF-LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQL--GS 57 M F L G+ I+V GVA+K SIA+GIA+++H GA L FTY ++L+ V E A L Sbjct: 1 MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRND 60 Query: 58 DIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAH 117 I+L CDV DA I+T FA + + G H I FA ++L G+Y+N R+GF +AH Sbjct: 61 SIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLN-TNRDGFLLAH 119 Query: 118 DISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAM 177 +ISSYS A+ KA R M+ G +++TL+YLG E +PNYNVMG+AKASL+A+V+Y+A + Sbjct: 120 NISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADL 179 Query: 178 GPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLS 237 G E +RVN+ISAGPIRTL+A GI DF +L E P+RRT T E+VG++AAFL SD+S Sbjct: 180 GKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMS 239 Query: 238 AGISGEVVHVDGGFSIAA 255 GI+GE +HVD GF I A Sbjct: 240 RGITGENLHVDSGFHITA 257 >5YCX-A nrPDB Length = 266 Score = 270 bits (692), Expect = 4e-73, Method: Composition-based stats. Identities = 119/258 (46%), Positives = 171/258 (66%), Gaps = 3/258 (1%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAA--QLGSD 58 M L GK +V GVA++ SIA+GIA+++H GA+L FTY ++L+ V E A + Sbjct: 3 MELLQGKTFVVMGVANQRSIAWGIARSLHNAGAKLIFTYAGERLERNVRELADTLEGQES 62 Query: 59 IVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHD 118 +VL CDV D + F + + G H I FA D L G++V+ +R+GF +A + Sbjct: 63 LVLPCDVTNDEELTACFETIKQEVGTIHGVAHCIAFANRDDLKGEFVD-TSRDGFLLAQN 121 Query: 119 ISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMG 178 IS++S A+A+ + ++ G +LTL+YLG ER + NYNVMG+AKASLEA+V+Y+AN +G Sbjct: 122 ISAFSLTAVAREAKKVMTEGGNILTLTYLGGERVVKNYNVMGVAKASLEASVKYLANDLG 181 Query: 179 PEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSA 238 G+RVNAISAGPIRTL+A G+ DF +L E P+RRT T E+VG++A FL SDL+ Sbjct: 182 QHGIRVNAISAGPIRTLSAKGVGDFNSILREIEERAPLRRTTTQEEVGDTAVFLFSDLAR 241 Query: 239 GISGEVVHVDGGFSIAAM 256 G++GE +HVD G+ I + Sbjct: 242 GVTGENIHVDSGYHILGL 259 >2YW9-A nrPDB Length = 261 Score = 267 bits (683), Expect = 4e-72, Method: Composition-based stats. Identities = 110/253 (43%), Positives = 168/253 (66%), Gaps = 1/253 (0%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 LSGK+ LV GV ++ S+ + IA + GAE+A +YQ ++L+ E+ A LG ++ + Sbjct: 6 LSGKKALVMGVTNQRSLGFAIAAKLKEAGAEVALSYQAERLRPEAEKLAEALGGALLFRA 65 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 DV +D +D +FA + + + D VH+I FAP + ++G Y++ R+ + +A ++S+YS Sbjct: 66 DVTQDEELDALFAGVKEAFGGLDYLVHAIAFAPREAMEGRYID-TRRQDWLLALEVSAYS 124 Query: 124 FVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVR 183 VA+A+ +L G ++TL+Y +E+ +P YNVM +AKA+LEA+VRY+A +GP+GVR Sbjct: 125 LVAVARRAEPLLREGGGIVTLTYYASEKVVPKYNVMAIAKAALEASVRYLAYELGPKGVR 184 Query: 184 VNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGE 243 VNAISAGP+RT+AA I F KM P+RR +T E+VGN FL S L++GI+GE Sbjct: 185 VNAISAGPVRTVAARSIPGFTKMYDRVAQTAPLRRNITQEEVGNLGLFLLSPLASGITGE 244 Query: 244 VVHVDGGFSIAAM 256 VV+VD G+ I M Sbjct: 245 VVYVDAGYHIMGM 257 >4NK4-A nrPDB Length = 301 Score = 266 bits (680), Expect = 8e-72, Method: Composition-based stats. Identities = 104/258 (40%), Positives = 168/258 (65%), Gaps = 1/258 (0%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 60 + L GKR L+ GVA+ SIA+GIA+ +H GA+LAF+YQ + + R++ A + SD + Sbjct: 36 INILKGKRGLIMGVANDHSIAWGIAKVLHSAGAQLAFSYQGESIGKRLKPLALTVDSDFM 95 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 + C+V + +S+D +F + + W D VHSI F+ ++L G Y N +R+ F +S Sbjct: 96 IPCNVEDPSSMDLLFERIKERWETLDFVVHSIAFSDKNELRGPYYN-TSRDNFIQTMLVS 154 Query: 121 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 +SF + + ++ G A++TL+Y G+ R +PNYN M AK++LE++ +Y+A G Sbjct: 155 CFSFTEIVRRAAQLMPHGGAMITLTYGGSMRVVPNYNAMAPAKSALESSTKYLACDYGGM 214 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 +R+NAISAGP+RTLA + I + R + A + +P++RTV++ED+GNSA +L S LS G+ Sbjct: 215 NIRINAISAGPVRTLAGASISNGRDIAAWSKENSPLKRTVSLEDIGNSALYLLSYLSNGV 274 Query: 241 SGEVVHVDGGFSIAAMNE 258 +GE+ +VD G++I AM Sbjct: 275 TGEIHYVDCGYNIVAMPS 292 >2PD3-A nrPDB Length = 275 Score = 259 bits (662), Expect = 8e-70, Method: Composition-based stats. Identities = 120/262 (45%), Positives = 174/262 (66%), Gaps = 1/262 (0%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 60 MGFL GK+ L+ GVA+ SIAYGIAQ+ +GA LAFTY N+ L+ RV A +L S V Sbjct: 1 MGFLKGKKGLIVGVANNKSIAYGIAQSCFNQGATLAFTYLNESLEKRVRPIAQELNSPYV 60 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 + DV+++ +++ + K D VHS+ FAP + L+G + ++ F A +IS Sbjct: 61 YELDVSKEEHFKSLYNSVKKDLGSLDFIVHSVAFAPKEALEGSLLE-TSKSAFNTAMEIS 119 Query: 121 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 YS + + + +LN G+++LTLSYLG+ + + +YNVMGLAKA+LE+ VRY+A +G Sbjct: 120 VYSLIELTNTLKPLLNNGASVLTLSYLGSTKYMAHYNVMGLAKAALESAVRYLAVDLGKH 179 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 +RVNA+SAGPIRTLA+SGI DFR +L E P+R+ V++E+VGN+ +L S LS+G+ Sbjct: 180 HIRVNALSAGPIRTLASSGIADFRMILKWNEINAPLRKNVSLEEVGNAGMYLLSSLSSGV 239 Query: 241 SGEVVHVDGGFSIAAMNELELK 262 SGEV VD G+ + M +E K Sbjct: 240 SGEVHFVDAGYHVMGMGAVEEK 261 >4ALL-A nrPDB Length = 277 Score = 245 bits (627), Expect = 1e-65, Method: Composition-based stats. Identities = 111/254 (43%), Positives = 163/254 (64%), Gaps = 3/254 (1%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQL--GSD 58 M L K ++ G+A+K SIA+G+A+ + + GA+L FTY+ ++ + +E+ QL Sbjct: 22 MLNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEA 81 Query: 59 IVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHD 118 + Q DV D + F ++GK DG HSI FA + L G + + +REGF +A D Sbjct: 82 HLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRF-SETSREGFLLAQD 140 Query: 119 ISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMG 178 ISSYS +A + ++ G +++ +YLG E A+ NYNVMG+AKASLEANV+Y+A +G Sbjct: 141 ISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLG 200 Query: 179 PEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSA 238 P+ +RVNAISAGPIRTL+A G+ F +L E P++R V +VG +AA+L SDLS+ Sbjct: 201 PDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSS 260 Query: 239 GISGEVVHVDGGFS 252 G++GE +HVD GF Sbjct: 261 GVTGENIHVDSGFH 274 >2PNF-A nrPDB Length = 248 Score = 237 bits (606), Expect = 3e-63, Method: Composition-based stats. Identities = 56/252 (22%), Positives = 105/252 (41%), Gaps = 13/252 (5%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQ-NDKLKGRVEEFAAQLGSDIV-L 61 L GK LVTG S I IA+ + G+ + T ++ K EE A + G + Sbjct: 5 LQGKVSLVTG--STRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGV 62 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 + ++ + SI+ F E+ + D V++ G ++ ++ ++ Sbjct: 63 EMNLLSEESINKAFEEIYNLVDGIDILVNNAGITRDKLF-----LRMSLLDWEEVLKVNL 117 Query: 122 YSFVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 + + + ++ +S + KA L + +A + P Sbjct: 118 TGTFLVTQNSLRKMIKQRWGRIVNISSVVGFTGNVGQVNYSTTKAGLIGFTKSLAKELAP 177 Query: 180 EGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAG 239 V VNA++ G I T + + ++ + P+ R + E+V N FLCS+L++ Sbjct: 178 RNVLVNAVAPGFIETDMTAVLS--EEIKQKYKEQIPLGRFGSPEEVANVVLFLCSELASY 235 Query: 240 ISGEVVHVDGGF 251 I+GEV+HV+GG Sbjct: 236 ITGEVIHVNGGM 247 >3OSU-A nrPDB Length = 246 Score = 233 bits (596), Expect = 4e-62, Method: Composition-based stats. Identities = 56/251 (22%), Positives = 99/251 (39%), Gaps = 13/251 (5%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN--DKLKGRVEEFAAQLGSDIVLQCD 64 K LVTG + I IA + EG +A Y +K + VEE A+ +Q + Sbjct: 5 KSALVTGAS--RGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQAN 62 Query: 65 VAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSF 124 VA+ + M E+ + D V++ G + L + + + D + Sbjct: 63 VADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLL-----MRMKEQEWDDVIDTNLKGV 117 Query: 125 VAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGV 182 + + A++ LS + P KA + + A + G+ Sbjct: 118 FNCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGI 177 Query: 183 RVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISG 242 VNA++ G I + + D ++ P+ R D+ N+ AFL SD + I+G Sbjct: 178 TVNAVAPGFIVSDMTDALSD--ELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITG 235 Query: 243 EVVHVDGGFSI 253 + +HV+GG + Sbjct: 236 QTIHVNGGMYM 246 >2HQ1-A nrPDB Length = 247 Score = 230 bits (588), Expect = 3e-61, Method: Composition-based stats. Identities = 55/254 (21%), Positives = 102/254 (40%), Gaps = 13/254 (5%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTY--QNDKLKGRVEEFAAQLGSDIVL 61 L GK +VTG S + IA + GA + + L EEF A + +V Sbjct: 3 LKGKTAIVTG--SSRGLGKAIAWKLGNMGANIVLNGSPASTSLDATAEEFKAAGINVVVA 60 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 + DV ++ M + + D V++ G + ++ + + + + Sbjct: 61 KGDVKNPEDVENMVKTAMDAFGRIDILVNNAGITRDTLM-----LKMSEKDWDDVLNTNL 115 Query: 122 YSFVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 S KA ++ ++ ++ + +KA L + +A Sbjct: 116 KSAYLCTKAVSKIMLKQKSGKIINITSIAGIIGNAGQANYAASKAGLIGFTKSIAKEFAA 175 Query: 180 EGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAG 239 +G+ NA++ G I+T + D K+ P++R T E+V N FL SD S Sbjct: 176 KGIYCNAVAPGIIKTDMTDVLPD--KVKEMYLNNIPLKRFGTPEEVANVVGFLASDDSNY 233 Query: 240 ISGEVVHVDGGFSI 253 I+G+V+++DGG + Sbjct: 234 ITGQVINIDGGLVM 247 >2UVD-A nrPDB Length = 246 Score = 230 bits (586), Expect = 6e-61, Method: Composition-based stats. Identities = 55/255 (21%), Positives = 99/255 (38%), Gaps = 13/255 (5%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGR--VEEFAAQLGSDIV 60 L GK LVTG + I IA + ++GA + Y ++ K V+E I Sbjct: 1 MLKGKVALVTGAS--RGIGRAIAIDLAKQGANVVVNYAGNEQKANEVVDEIKKLGSDAIA 58 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 ++ DVA + M + V+ + D V++ G + L + E + + + Sbjct: 59 VRADVANAEDVTNMVKQTVDVFGQVDILVNNAGVTKDNLL-----MRMKEEEWDTVINTN 113 Query: 121 SYSFVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMG 178 KA + ++ ++ + P AKA + + A + Sbjct: 114 LKGVFLCTKAVSRFMMRQRHGRIVNIASVVGVTGNPGQANYVAAKAGVIGLTKTSAKELA 173 Query: 179 PEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSA 238 + VNAI+ G I T + + A + P + +D+ N+ F SD S Sbjct: 174 SRNITVNAIAPGFIATDMTDVLD--ENIKAEMLKLIPAAQFGEAQDIANAVTFFASDQSK 231 Query: 239 GISGEVVHVDGGFSI 253 I+G+ ++VDGG + Sbjct: 232 YITGQTLNVDGGMVM 246 >4JRO-A nrPDB Length = 271 Score = 227 bits (579), Expect = 4e-60, Method: Composition-based stats. Identities = 56/254 (22%), Positives = 100/254 (39%), Gaps = 13/254 (5%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN--DKLKGRVEEFAAQLGSDIVL 61 L GK +VTG + I IA + +EGA + F Y + + + A + Sbjct: 27 LQGKVAVVTGGS--RGIGRDIAINLAKEGANIFFNYNGSPEAAEETAKLVAEHGVEVEAM 84 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 + +VA +D F + + + + D V++ G + L + + + +I+ Sbjct: 85 KANVAIAEDVDAFFKQAIERFGRVDILVNNAGITRDNLL-----MRMKEDEWDDVININL 139 Query: 122 YSFVAMAKACRS--MLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 KA M ++ ++ + +KA + + A + P Sbjct: 140 KGTFLCTKAVSRTMMKQRAGKIINMASVVGLIGNAGQANYVASKAGVIGLTKTTARELAP 199 Query: 180 EGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAG 239 G+ VNA++ G I T + K A P+ T ED+ N+ FL SD S Sbjct: 200 RGINVNAVAPGFITTDMTDKLD--EKTKEAMLAQIPLGAYGTTEDIANAVLFLASDASKY 257 Query: 240 ISGEVVHVDGGFSI 253 I+G+ + VDGG + Sbjct: 258 ITGQTLSVDGGMVM 271 >3RSH-A nrPDB Length = 251 Score = 226 bits (577), Expect = 7e-60, Method: Composition-based stats. Identities = 55/253 (21%), Positives = 101/253 (39%), Gaps = 13/253 (5%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 L GK LVTG + I IA+ + GA++ T ++ + ++ G + L Sbjct: 10 LEGKVALVTGAS--RGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMAL-- 65 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 +V SI+ + + + D V++ G + L + E + + + S Sbjct: 66 NVTNPESIEAVLKAITDEFGGVDILVNNAGITRDNLL-----MRMKEEEWSDIMETNLTS 120 Query: 124 FVAMAKACRS--MLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 ++KA M ++ + + AKA + + MA + G Sbjct: 121 IFRLSKAVLRGMMKKRQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVASRG 180 Query: 182 VRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGIS 241 V VN ++ G I T + D ++ A P R ++ ++ AFL S +A I+ Sbjct: 181 VTVNTVAPGFIETDMTKALNDEQRTA--TLAQVPAGRLGDPREIASAVAFLASPEAAYIT 238 Query: 242 GEVVHVDGGFSIA 254 GE +HV+GG + Sbjct: 239 GETLHVNGGMYMI 251 >3O4R-A nrPDB Length = 261 Score = 225 bits (574), Expect = 2e-59, Method: Composition-based stats. Identities = 59/250 (23%), Positives = 108/250 (43%), Gaps = 9/250 (3%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDK-LKGRVEEFAAQLGSDIVLQ 62 L+ K LVT AS I + IA+ + ++GA + + + + + V + S Sbjct: 13 LANKVALVT--ASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTV 70 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSY 122 C V + + + A K+ D V + P + VT E + DI+ Sbjct: 71 CHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPF----FGSIMDVTEEVWDKTLDINVK 126 Query: 123 SFVAMAKACRSMLNP--GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 + M KA + G +++ +S + A P ++ ++K +L + +A + P Sbjct: 127 APALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPR 186 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 +RVN ++ G I+T + + ++ + IRR ED +FLCS+ ++ I Sbjct: 187 NIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYI 246 Query: 241 SGEVVHVDGG 250 +GE V V GG Sbjct: 247 TGETVVVGGG 256 >2ZAT-A nrPDB Length = 260 Score = 220 bits (562), Expect = 3e-58, Method: Composition-based stats. Identities = 61/250 (24%), Positives = 108/250 (43%), Gaps = 9/250 (3%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN-DKLKGRVEEFAAQLGSDIVLQ 62 L K LVT AS I IA+ + ++GA + + + + + V + S Sbjct: 12 LENKVALVT--ASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTV 69 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSY 122 C V + + + A + D V + P G+ ++A T E + ++ Sbjct: 70 CHVGKAEDRERLVAMAVNLHGGVDILVSNAAVNP---FFGNIIDA-TEEVWDKILHVNVK 125 Query: 123 SFVAMAKACRSMLNP--GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 + V M KA + G ++L +S +GA PN ++K +L + +A + P Sbjct: 126 ATVLMTKAVVPEMEKRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAPR 185 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 +RVN ++ G I+T + + + + + IRR ED +FLCS+ ++ I Sbjct: 186 NIRVNCLAPGLIKTNFSQVLWMDKARKEYMKESLRIRRLGNPEDCAGIVSFLCSEDASYI 245 Query: 241 SGEVVHVDGG 250 +GE V V GG Sbjct: 246 TGETVVVGGG 255 >3WOH-A nrPDB Length = 251 Score = 220 bits (562), Expect = 4e-58, Method: Composition-based stats. Identities = 60/256 (23%), Positives = 100/256 (39%), Gaps = 15/256 (5%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDK--LKGRVEEFAAQLGSDI 59 G LSGK LVTG + + +A + R+GA +A Y +D K E G+ Sbjct: 7 GALSGKVALVTGGS--RGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLGGTAR 64 Query: 60 VLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDI 119 +CDV++ + + D V++ G ++ E + + Sbjct: 65 SYRCDVSDAEQVTRCVKAVTADLGPVDILVNNAGIIRD-----GLAASIKDEDYDAVMNT 119 Query: 120 SSYS--FVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAM 177 + A + +++ +S + AKA L + +A + Sbjct: 120 NLKGAFLFIKACYFGFIRKRSGSIINISSVSGVFGSAGQANYASAKAGLIGLTKSIAKEL 179 Query: 178 GPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLS 237 VR NA++ G I T + D K L P+RR ++V AFL D S Sbjct: 180 AERNVRCNAVAPGLIATDMTQDLVDDSKRLD----PVPMRRFGRPDEVAGLVAFLAGDES 235 Query: 238 AGISGEVVHVDGGFSI 253 + I+G+VV VDGG ++ Sbjct: 236 SYITGQVVCVDGGMAM 251 >3EMK-A nrPDB Length = 246 Score = 220 bits (561), Expect = 4e-58, Method: Composition-based stats. Identities = 49/257 (19%), Positives = 109/257 (42%), Gaps = 15/257 (5%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 60 M L+G++ LVTG + IA+A+H +GA + ++ +++E AA+LG I Sbjct: 2 MFDLTGRKALVTGATG--GLGEAIARALHAQGAIVGLHGTREE---KLKELAAELGERIF 56 Query: 61 L-QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDI 119 + ++++ ++ + + + D V++ G ++ E + + Sbjct: 57 VFPANLSDREAVKALGQKAEEEMGGVDILVNNAGITRD-----GLFVRMSDEDWDAVLTV 111 Query: 120 SSYSFVAMAKACRS--MLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAM 177 + S + + M ++ ++ + P +KA L + +A + Sbjct: 112 NLTSVFNLTRELTHPMMRRRNGRIINITSIVGVTGNPGQANYCASKAGLIGFSKSLAQEI 171 Query: 178 GPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLS 237 V VN I+ G I + + + +K P++R D+ + +L SD + Sbjct: 172 ASRNVTVNCIAPGFIESAMTGKLNEKQK--DAIMGNIPMKRMGVGADIAAAVVYLASDEA 229 Query: 238 AGISGEVVHVDGGFSIA 254 A ++G+ +HV+GG ++ Sbjct: 230 AYVTGQTLHVNGGMAMI 246 >3LYL-A nrPDB Length = 247 Score = 217 bits (553), Expect = 4e-57, Method: Composition-based stats. Identities = 53/254 (20%), Positives = 106/254 (41%), Gaps = 12/254 (4%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLG-SDIVLQ 62 L+ K LVTG + I + +A A+ +GA + T + + E + G L Sbjct: 3 LNEKVALVTGAS--RGIGFEVAHALASKGATVVGTATSQASAEKFENSMKEKGFKARGLV 60 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSY 122 ++++ SI FAE+ D V++ G + + ++ + ++ + + Sbjct: 61 LNISDIESIQNFFAEIKAENLAIDILVNNAGITRDNLM-----MRMSEDEWQSVINTNLS 115 Query: 123 SFVAMAKAC--RSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 S M+K C M ++++ + P AKA + + +A + Sbjct: 116 SIFRMSKECVRGMMKKRWGRIISIGSVVGSAGNPGQTNYCAAKAGVIGFSKSLAYEVASR 175 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 + VN ++ G I T + D +K + P + +D+ + AFL S+ + I Sbjct: 176 NITVNVVAPGFIATDMTDKLTDEQK--SFIATKIPSGQIGEPKDIAAAVAFLASEEAKYI 233 Query: 241 SGEVVHVDGGFSIA 254 +G+ +HV+GG +A Sbjct: 234 TGQTLHVNGGMYMA 247 >4M8S-A nrPDB Length = 248 Score = 217 bits (553), Expect = 4e-57, Method: Composition-based stats. Identities = 59/253 (23%), Positives = 107/253 (42%), Gaps = 12/253 (4%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 LSGK LVTG + I IA + GA++ T ++ + E AQ G + + Sbjct: 6 LSGKIALVTGAS--RGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGGEGRV-L 62 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 + AE +++ + A++ K + K D V++ G + L + E + ++ S Sbjct: 63 NSAEPETVENLIADIEKTFGKLDILVNNAGITRDNLL-----MRMKEEEWDDIMQVNLKS 117 Query: 124 FVAMAKACRS--MLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 +KA M ++ ++ + AKA L + MA +G G Sbjct: 118 VFRASKAVLRGMMKQRAGRIINITSVVGVMGNAGQTNYAAAKAGLIGFSKSMAREVGSRG 177 Query: 182 VRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGIS 241 + VN ++ G I T + + A T + R +D+ ++ FL SD + I+ Sbjct: 178 ITVNCVAPGFIDTDMTRAL--PEETRQTFTAQTALGRFGDAQDIADAVLFLASDQAKYIT 235 Query: 242 GEVVHVDGGFSIA 254 G+ +HV+GG + Sbjct: 236 GQTLHVNGGMLMP 248 >1Q7C-A nrPDB Length = 244 Score = 216 bits (551), Expect = 6e-57, Method: Composition-based stats. Identities = 58/253 (22%), Positives = 110/253 (43%), Gaps = 13/253 (5%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 GK LVTG + I IA+ + GA++ T ++ + ++ G ++L Sbjct: 3 FEGKIALVTGAS--RGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLML-- 58 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 +V + ASI+++ ++ + + D V++ G + L + E + + + S Sbjct: 59 NVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLL-----MRMKDEEWNDIIETNLSS 113 Query: 124 FVAMAKACRS--MLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 ++KA M ++T+ + AKA L + +A + G Sbjct: 114 VFRLSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANFAAAKAGLIGFSKSLAREVASRG 173 Query: 182 VRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGIS 241 + VN ++ G I T + D ++ A A P R +++ N+ AFL SD +A I+ Sbjct: 174 ITVNVVAPGFIETDMTRALSDDQR--AGILAQVPAGRLGGAQEIANAVAFLASDEAAYIT 231 Query: 242 GEVVHVDGGFSIA 254 GE +HV+GG + Sbjct: 232 GETLHVNGGMYMV 244 >5CDY-A nrPDB Length = 244 Score = 215 bits (549), Expect = 1e-56, Method: Composition-based stats. Identities = 59/253 (23%), Positives = 110/253 (43%), Gaps = 13/253 (5%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 GK LVTG + I IA+ + GA + T ++K + + + G ++L Sbjct: 3 FEGKIALVTGAS--RGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGKGLML-- 58 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 +V + SIDT+ A + + + D V++ G + L + + ++ D + S Sbjct: 59 NVVDPTSIDTVLATIRAEFGEVDILVNNAGITRDNLL-----MRMKDDEWQDIIDTNLTS 113 Query: 124 FVAMAKACRS--MLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 ++KA M ++T+ + AKA + + +A + G Sbjct: 114 VFRLSKAVMRAMMKKRFGRIITIGSVVGTMGNAGQVNYAAAKAGVIGFSKSLAREVASRG 173 Query: 182 VRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGIS 241 + VN ++ G I T + D ++ A A P R +++ ++ AFL SD ++ IS Sbjct: 174 ITVNVVAPGFIETDMTRTLTDDQR--AGILAQVPANRLGDAKEIASAVAFLASDEASYIS 231 Query: 242 GEVVHVDGGFSIA 254 GE +HV+GG + Sbjct: 232 GETLHVNGGMYMI 244 >2EW8-A nrPDB Length = 249 Score = 215 bits (548), Expect = 2e-56, Method: Composition-based stats. Identities = 63/253 (24%), Positives = 109/253 (43%), Gaps = 14/253 (5%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQ 62 L K ++TG A+ I IA+ EGA++A + + ++ Sbjct: 4 RLKDKLAVITGGAN--GIGRAIAERFAVEGADIAIADLVPAPEAEAA-IRNLGRRVLTVK 60 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSY 122 CDV++ ++ ++ + + D V++ G P D +T E +K +I+ Sbjct: 61 CDVSQPGDVEAFGKQVISTFGRCDILVNNAGIYPLIPFD-----ELTFEQWKKTFEINVD 115 Query: 123 SFVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 S MAKA + N ++ L+ I Y KA+ R +A+ +G + Sbjct: 116 SGFLMAKAFVPGMKRNGWGRIINLTSTTYWLKIEAYTHYISTKAANIGFTRALASDLGKD 175 Query: 181 GVRVNAISAGPIRTLA--ASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSA 238 G+ VNAI+ +RT AS + +L + P R D+ +AAFL SD ++ Sbjct: 176 GITVNAIAPSLVRTATTEASALSAMFDVLPNMLQAIP--RLQVPLDLTGAAAFLASDDAS 233 Query: 239 GISGEVVHVDGGF 251 I+G+ + VDGG Sbjct: 234 FITGQTLAVDGGM 246 >3OIC-A nrPDB Length = 258 Score = 213 bits (544), Expect = 4e-56, Method: Composition-based stats. Identities = 67/256 (26%), Positives = 119/256 (46%), Gaps = 11/256 (4%) Query: 5 SGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKG--RVEEFAAQLGSDIVLQ 62 K LVTG + + A I + G + Y K EE +V++ Sbjct: 3 QNKCALVTGSSRGVGKAAAI--RLAENGYNIVINYARSKKAALETAEEIEKLGVKVLVVK 60 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSY 122 +V + A I MF ++ + + + D FV++ V + + +I++ Sbjct: 61 ANVGQPAKIKEMFQQIDETFGRLDVFVNNAASG-----VLRPVMELEETHWDWTMNINAK 115 Query: 123 SFVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 + + A+ ++ N G ++++S LG+ R + NY +G++KA+LEA RY+A + P+ Sbjct: 116 ALLFCAQEAAKLMEKNGGGHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAVELSPK 175 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 + VNA+S G I T A + +L TP R V I+D+ ++ FL S + I Sbjct: 176 QIIVNAVSGGAIDTDALKHFPNREDLLEDARQNTPAGRMVEIKDMVDTVEFLVSSKADMI 235 Query: 241 SGEVVHVDGGFSIAAM 256 G+ + VDGG S+ + Sbjct: 236 RGQTIIVDGGRSLLVL 251 >3R3S-A nrPDB Length = 294 Score = 213 bits (543), Expect = 5e-56, Method: Composition-based stats. Identities = 55/256 (21%), Positives = 111/256 (43%), Gaps = 9/256 (3%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTY--QNDKLKGRVEEFAAQLG-SD 58 G L ++ LVTG S I A A REGA++A Y ++ +V+ + G Sbjct: 45 GRLKDRKALVTGGDS--GIGRAAAIAYAREGADVAINYLPAEEEDAQQVKALIEECGRKA 102 Query: 59 IVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHD 118 ++L D+++++ ++ + + D G Q + +T E F+ Sbjct: 103 VLLPGDLSDESFARSLVHKAREALGGLDIL----ALVAGKQTAIPEIKDLTSEQFQQTFA 158 Query: 119 ISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMG 178 ++ ++ + + +L G++++T S + A + P+ KA++ R +A + Sbjct: 159 VNVFALFWITQEAIPLLPKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVA 218 Query: 179 PEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSA 238 +G+RVN ++ GPI T + + TP++R ++ +L S S+ Sbjct: 219 EKGIRVNIVAPGPIWTALQISGGQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQESS 278 Query: 239 GISGEVVHVDGGFSIA 254 ++ EV V GG + Sbjct: 279 YVTAEVHGVCGGEHLG 294 >2C07-A nrPDB Length = 285 Score = 212 bits (540), Expect = 1e-55, Method: Composition-based stats. Identities = 53/252 (21%), Positives = 92/252 (36%), Gaps = 14/252 (5%) Query: 5 SGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKL-KGRVEEFAAQLGSDIVLQC 63 K LVTG I IA+ + + + + + K V+E + Sbjct: 43 ENKVALVTGA--GRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKSFGYESSGYAG 100 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQ---LDGDYVNAVTREGFKIAHDIS 120 DV++ I + ++ D V++ G + + D V R I+ Sbjct: 101 DVSKKEEISEVINKILTEHKNVDILVNNAGITRDNLFLRMKNDEWEDVLRTNLNSLFYIT 160 Query: 121 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 + R + N ++ +S + +KA + + +A + Sbjct: 161 QP------ISKRMINNRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKELASR 214 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 + VNAI+ G I + I ++ + + P R T E+V N A FL SD S I Sbjct: 215 NITVNAIAPGFISSDMTDKIS--EQIKKNIISNIPAGRMGTPEEVANLACFLSSDKSGYI 272 Query: 241 SGEVVHVDGGFS 252 +G V +DGG S Sbjct: 273 NGRVFVIDGGLS 284 >3GRP-A nrPDB Length = 266 Score = 211 bits (538), Expect = 2e-55, Method: Composition-based stats. Identities = 48/257 (18%), Positives = 108/257 (42%), Gaps = 15/257 (5%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 60 M L+G++ LVTG I IA+ H +GA + + +++E AA LG D+ Sbjct: 22 MFKLTGRKALVTGATG--GIGEAIARCFHAQGAIVGLHGTRED---KLKEIAADLGKDVF 76 Query: 61 L-QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDI 119 + ++++ SI + + D V++ G + + + + Sbjct: 77 VFSANLSDRKSIKQLAEVAEREMEGIDILVNNAGITRD-----GLFVRMQDQDWDDVLAV 131 Query: 120 SSYSFVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAM 177 + + + + + ++ ++ + P AKA L + +A + Sbjct: 132 NLTAASTLTRELIHSMMRRRYGRIINITSIVGVVGNPGQTNYCAAKAGLIGFSKALAQEI 191 Query: 178 GPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLS 237 + VN I+ G I++ + + +K A+ P++R E++ + +L SD + Sbjct: 192 ASRNITVNCIAPGFIKSAMTDKLNEKQK--EAIMAMIPMKRMGIGEEIAFATVYLASDEA 249 Query: 238 AGISGEVVHVDGGFSIA 254 A ++G+ +H++GG ++ Sbjct: 250 AYLTGQTLHINGGMAMI 266 >3FTP-A nrPDB Length = 270 Score = 211 bits (537), Expect = 3e-55, Method: Composition-based stats. Identities = 54/254 (21%), Positives = 98/254 (38%), Gaps = 14/254 (5%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRV-EEFAAQLGSDIVLQ 62 L + +VTG + I IA + R GA + T + + F Sbjct: 26 LDKQVAIVTGAS--RGIGRAIALELARRGAMVIGTATTEAGAEGIGAAFKQAGLEGRGAV 83 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQ---LDGDYVNAVTREGFKIAHDI 119 +V + ++D + K + + V++ G + D +AV K + Sbjct: 84 LNVNDATAVDALVESTLKEFGALNVLVNNAGITQDQLAMRMKDDEWDAVIDTNLKAVFRL 143 Query: 120 SSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 S M KA G ++ ++ + P AKA + R +A +G Sbjct: 144 SRAVLRPMMKA------RGGRIVNITSVVGSAGNPGQVNYAAAKAGVAGMTRALAREIGS 197 Query: 180 EGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAG 239 G+ VN ++ G I T G+ ++ + P+ R + ED+ ++ AFL S + Sbjct: 198 RGITVNCVAPGFIDTDMTKGLPQEQQTA--LKTQIPLGRLGSPEDIAHAVAFLASPQAGY 255 Query: 240 ISGEVVHVDGGFSI 253 I+G +HV+GG + Sbjct: 256 ITGTTLHVNGGMFM 269 >1GEE-A nrPDB Length = 261 Score = 209 bits (533), Expect = 8e-55, Method: Composition-based stats. Identities = 48/255 (18%), Positives = 109/255 (42%), Gaps = 12/255 (4%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN--DKLKGRVEEFAAQLGSDIVL 61 L GK +++TG ++ + +A E A++ Y++ D+ +EE G I + Sbjct: 5 LEGKVVVITGSST--GLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKVGGEAIAV 62 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS- 120 + DV ++ + + K + K D +++ G + ++ + D + Sbjct: 63 KGDVTVESDVINLVQSAIKEFGKLDVMINNAGLENPV-----SSHEMSLSDWNKVIDTNL 117 Query: 121 SYSFVAMAKACRSMLN--PGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMG 178 + +F+ +A + + ++ +S + + P + +K ++ +A Sbjct: 118 TGAFLGSREAIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALEYA 177 Query: 179 PEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSA 238 P+G+RVN I G I T + + A E++ P+ E++ AA+L S ++ Sbjct: 178 PKGIRVNNIGPGAINTPINAEKFADPEQRADVESMIPMGYIGEPEEIAAVAAWLASSEAS 237 Query: 239 GISGEVVHVDGGFSI 253 ++G + DGG ++ Sbjct: 238 YVTGITLFADGGMTL 252 >3F9I-A nrPDB Length = 249 Score = 209 bits (533), Expect = 9e-55, Method: Composition-based stats. Identities = 50/254 (19%), Positives = 110/254 (43%), Gaps = 19/254 (7%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQ- 62 L+GK L+TG +S I IA+ +H+ G+++ + N++ +++ L + ++ Sbjct: 12 LTGKTSLITGASS--GIGSAIARLLHKLGSKVIISGSNEE---KLKSLGNALKDNYTIEV 66 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSY 122 C++A + ++ D V + G + + F DI+ Sbjct: 67 CNLANKEECSNLISKTSN----LDILVCNAGITSDTL-----AIRMKDQDFDKVIDINLK 117 Query: 123 S-FVAMAKACRSMLNPG-SALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 + F+ +A + M+ ++ +S + P +KA L + ++ + Sbjct: 118 ANFILNREAIKKMIQKRYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYEVATR 177 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 G+ VNA++ G I++ + + ++ P+ EDV + AFL S+ ++ I Sbjct: 178 GITVNAVAPGFIKSDMTDKLNEKQR--EAIVQKIPLGTYGIPEDVAYAVAFLASNNASYI 235 Query: 241 SGEVVHVDGGFSIA 254 +G+ +HV+GG + Sbjct: 236 TGQTLHVNGGMLMV 249 >5ITV-A nrPDB Length = 255 Score = 208 bits (531), Expect = 1e-54, Method: Composition-based stats. Identities = 55/259 (21%), Positives = 99/259 (38%), Gaps = 20/259 (7%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 L+ K +L+TG AS I Y QA + A + D+ +G +Q Sbjct: 5 LTDKTVLITGGAS--GIGYAAVQAFLGQQANVVVADI-DEAQGEAMVRKENNDRLHFVQT 61 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGF---APGDQLDGDYVNAVTREGFKIAHDIS 120 D+ ++A+ + D +++ G AP +++ N V + Sbjct: 62 DITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNL------- 114 Query: 121 SYSFVAMAKACRSMLNPG-SALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 + F+ A + ML G ++ +G A P+ +K + + MA Sbjct: 115 TGMFLMSKHALKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAK 174 Query: 180 EGVRVNAISAGPIRTLAA------SGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLC 233 +RVN + G I T + ++ V P+ R E++ N FL Sbjct: 175 HQIRVNCVCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRLGKPEEIANVMLFLA 234 Query: 234 SDLSAGISGEVVHVDGGFS 252 SDLS+ ++G + DGG++ Sbjct: 235 SDLSSYMTGSAITADGGYT 253 >4DMM-A nrPDB Length = 269 Score = 208 bits (531), Expect = 2e-54, Method: Composition-based stats. Identities = 57/256 (22%), Positives = 110/256 (42%), Gaps = 17/256 (6%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDK--LKGRVEEFAAQLGSDIVL 61 L+ + LVTG + I IA + GA++A Y + V AA G + Sbjct: 26 LTDRIALVTGAS--RGIGRAIALELAAAGAKVAVNYASSAGAADEVVAAIAAAGGEAFAV 83 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 + DV++++ ++ +FA + + W + D V++ G L + R+ ++ D++ Sbjct: 84 KADVSQESEVEALFAAVIERWGRLDVLVNNAGITRDTLL-----LRMKRDDWQSVLDLNL 138 Query: 122 YSFVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 ++A ++ ++ ++ + E P AKA + + +A + Sbjct: 139 GGVFLCSRAAAKIMLKQRSGRIINIASVVGEMGNPGQANYSAAKAGVIGLTKTVAKELAS 198 Query: 180 EGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSD-LSA 238 G+ VNA++ G I T S V P+ R +V FL +D +A Sbjct: 199 RGITVNAVAPGFIATDMTS-----ELAAEKLLEVIPLGRYGEAAEVAGVVRFLAADPAAA 253 Query: 239 GISGEVVHVDGGFSIA 254 I+G+V+++DGG +A Sbjct: 254 YITGQVINIDGGLVMA 269 >6NRP-A nrPDB Length = 263 Score = 208 bits (530), Expect = 2e-54, Method: Composition-based stats. Identities = 55/250 (22%), Positives = 102/250 (40%), Gaps = 17/250 (6%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGR--VEEFAAQLGSDIVLQCD 64 +RILVTG S I IA + + G ++ ++ + + V+E A + L D Sbjct: 25 RRILVTG--SSRGIGKAIALQLAKAGFDVTVHARSRQAEAEQVVQEIQALGQNSHYLMFD 82 Query: 65 VAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSF 124 V E ++ + + + F G V + G A+T + + S F Sbjct: 83 VNERQTVQQILEQDVEQHGGFYGVVLNAGLTHDGAFP-----ALTDQDWDEVISTSLDGF 137 Query: 125 VAMAK---ACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 + K L G ++TLS + AKA L + +A + Sbjct: 138 YNVLKPLIMPMIHLRKGGRIVTLSSVSGIMGNRGQVNYSAAKAGLIGATKALALELAKRK 197 Query: 182 VRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGIS 241 + VN ++ G I T + ++ H + P++R +++V + FLCSD ++ ++ Sbjct: 198 ITVNCVAPGLIETEMVT-----DEVKEHALKMIPLQRMGQVDEVASVVKFLCSDEASYVT 252 Query: 242 GEVVHVDGGF 251 +V+ V+GG Sbjct: 253 RQVISVNGGL 262 >2NM0-A nrPDB Length = 253 Score = 207 bits (528), Expect = 3e-54, Method: Composition-based stats. Identities = 50/250 (20%), Positives = 105/250 (42%), Gaps = 21/250 (8%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVA 66 + +LVTG I IA+A G ++A TY++ + + ++CD+ Sbjct: 22 RSVLVTGG--NRGIGLAIARAFADAGDKVAITYRSGEPPE----------GFLAVKCDIT 69 Query: 67 EDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS-SYSFV 125 + ++ + E+ + + + + G L ++ E F + + + +F Sbjct: 70 DTEQVEQAYKEIEETHGPVEVLIANAGVTKDQLL-----MRMSEEDFTSVVETNLTGTFR 124 Query: 126 AMAKACRSMLN-PGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRV 184 + +A R+ML ++ +S + +KA L R +A +G + Sbjct: 125 VVKRANRAMLRAKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARSLARELGSRNITF 184 Query: 185 NAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEV 244 N ++ G + T + D ++ A+ + P+ R E++ + FL SD ++ I+G V Sbjct: 185 NVVAPGFVDTDMTKVLTDEQR--ANIVSQVPLGRYARPEEIAATVRFLASDDASYITGAV 242 Query: 245 VHVDGGFSIA 254 + VDGG + Sbjct: 243 IPVDGGLGMG 252 >3AUT-A nrPDB Length = 269 Score = 207 bits (528), Expect = 4e-54, Method: Composition-based stats. Identities = 51/256 (19%), Positives = 104/256 (40%), Gaps = 16/256 (6%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN--DKLKGRVEEFAAQLGSDIVL 61 L K +++TG ++ + +A +E A++ Y N ++ +E G I++ Sbjct: 13 LKDKVVVITGGST--GLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQAIIV 70 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGF---APGDQLDGDYVNAVTREGFKIAHD 118 Q DV ++ + + K + D +++ G P +L D N V Sbjct: 71 QGDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNL----- 125 Query: 119 ISSYSFVAMAKACRSMLN--PGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANA 176 + +F+ +A + + ++ +S + P + +K ++ +A Sbjct: 126 --TGAFLGSREAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALE 183 Query: 177 MGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDL 236 P+G+RVN I G + T + A E++ P+ E+V AAFL S Sbjct: 184 YAPKGIRVNNIGPGAMNTPINAEKFADPVQRADVESMIPMGYIGKPEEVAAVAAFLASSQ 243 Query: 237 SAGISGEVVHVDGGFS 252 ++ ++G + DGG + Sbjct: 244 ASYVTGITLFADGGMT 259 >1AE1-A nrPDB Length = 273 Score = 206 bits (525), Expect = 8e-54, Method: Composition-based stats. Identities = 53/261 (20%), Positives = 108/261 (41%), Gaps = 17/261 (6%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQ- 62 L G LVTG + I Y I + + GA + +N+K E + G ++ Sbjct: 19 LKGTTALVTGGSK--GIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREKGLNVEGSV 76 Query: 63 CDVAEDASIDTMFAELGKVW-PKFDGFVHSIGFA---PGDQLDGDYVNAVTREGFKIAHD 118 CD+ D + + V+ K + V++ G N + F+ A+ Sbjct: 77 CDLLSRTERDKLMQTVAHVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFEAAYH 136 Query: 119 ISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMG 178 +S ++ + + ++ LS + A+P+ ++ +K ++ + +A Sbjct: 137 LSQIAYPLLKAS------QNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLACEWA 190 Query: 179 PEGVRVNAISAGPIRTL----AASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCS 234 + +RVN+++ G I T A ++ + + TP+ R ++V AFLC Sbjct: 191 KDNIRVNSVAPGVILTPLVETAIKKNPHQKEEIDNFIVKTPMGRAGKPQEVSALIAFLCF 250 Query: 235 DLSAGISGEVVHVDGGFSIAA 255 ++ I+G+++ DGGF+ Sbjct: 251 PAASYITGQIIWADGGFTANG 271 >4BO1-A nrPDB Length = 269 Score = 205 bits (522), Expect = 1e-53, Method: Composition-based stats. Identities = 57/254 (22%), Positives = 95/254 (37%), Gaps = 14/254 (5%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV-LQ 62 L GK LVTG + I IA + R GA + T + ++ E G + L Sbjct: 25 LQGKVALVTGAS--RGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLV 82 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQL---DGDYVNAVTREGFKIAHDI 119 DV+ D S+ + + + V++ G + L D V + + Sbjct: 83 LDVSSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEWFDVVNTNLNSLYRL 142 Query: 120 SSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 S M KA ++ + + AKA LE R +A +G Sbjct: 143 SKAVLRGMTKA------RWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGS 196 Query: 180 EGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAG 239 + VNA++ G I T + + ++ P+ R E++ FL SD +A Sbjct: 197 RAITVNAVAPGFIDTDMTRELPEAQR--EALLGQIPLGRLGQAEEIAKVVGFLASDGAAY 254 Query: 240 ISGEVVHVDGGFSI 253 ++G V V+GG + Sbjct: 255 VTGATVPVNGGMYM 268 >4MOW-A nrPDB Length = 256 Score = 205 bits (521), Expect = 2e-53, Method: Composition-based stats. Identities = 63/255 (24%), Positives = 111/255 (43%), Gaps = 10/255 (3%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKG--RVEEFAAQLGSD 58 M L+GK +VTG + I IA+A+ EGA + Y + K V G Sbjct: 9 MSKLAGKVAIVTGASK--GIGAAIAKALADEGAAVVVNYASSKAGADAVVSAITEAGGRA 66 Query: 59 IVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHD 118 + + DV++ A + + + + D V++ G + + A+T E ++ D Sbjct: 67 VAVGGDVSKAADAQRIVDTAIETYGRLDVLVNNSGVY-----EFAPIEAITEEHYRRQFD 121 Query: 119 ISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMG 178 + + + +A L G++++ +S + P V K +++A +A +G Sbjct: 122 TNVFGVLLTTQAAVKHLGEGASIINISSVVTSITPPASAVYSGTKGAVDAITGVLALELG 181 Query: 179 PEGVRVNAISAGPIRTLAA-SGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLS 237 P +RVNAI+ G I T S + A TP+ R D+ + A FL SD + Sbjct: 182 PRKIRVNAINPGMIVTEGTHSAGIIGSDLEAQVLGQTPLGRLGEPNDIASVAVFLASDDA 241 Query: 238 AGISGEVVHVDGGFS 252 ++GE + V GG + Sbjct: 242 RWMTGEHLVVSGGLN 256 >4RZH-A nrPDB Length = 247 Score = 205 bits (521), Expect = 2e-53, Method: Composition-based stats. Identities = 55/258 (21%), Positives = 97/258 (37%), Gaps = 17/258 (6%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQND--KLKGRVEEFAAQLGSD 58 M L+ + LVTG + I A A+ G ++ Y V E A G Sbjct: 1 MTALTAQVALVTGAS--RGIGKATALALAATGMKVVVNYAQSSTAADAVVAEIIANGGEA 58 Query: 59 IVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHD 118 I +Q +VA +D + + + D V++ G L + E ++ D Sbjct: 59 IAVQANVANADEVDQLIKTTLDKFSRIDVLVNNAGITRDTLL-----LRMKLEDWQAVID 113 Query: 119 ISSYSFVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANA 176 ++ KA ++ ++ ++ + P AKA + + +A Sbjct: 114 LNLTGVFLCTKAVSKLMLKQKSGRIINITSVAGMMGNPGQANYSAAKAGVIGFTKTVAKE 173 Query: 177 MGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSD- 235 + GV VNA++ G I T + P+ R E+V + FL +D Sbjct: 174 LASRGVTVNAVAPGFIATDMTENLN-----AEPILQFIPLARYGQPEEVAGTIRFLATDP 228 Query: 236 LSAGISGEVVHVDGGFSI 253 +A I+G+ +VDGG + Sbjct: 229 AAAYITGQTFNVDGGMVM 246 >1YXM-A nrPDB Length = 303 Score = 203 bits (518), Expect = 4e-53, Method: Composition-based stats. Identities = 53/263 (20%), Positives = 105/263 (39%), Gaps = 20/263 (7%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN-DKLKGRVEEFAAQLG---- 56 G L G+ +VTG A+ I I + + G+ + + ++LK +E A L Sbjct: 14 GLLQGQVAIVTGGAT--GIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQ 71 Query: 57 -SDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIG---FAPGDQLDGDYVNAVTREG 112 I +QC++ + ++ + + K + V++ G +P + + +AV Sbjct: 72 ARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETN 131 Query: 113 FKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRY 172 ++ A M G +++ + + + P G A+A + + Sbjct: 132 LTGTF------YMCKAVYSSWMKEHGGSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKS 184 Query: 173 MANAMGPEGVRVNAISAGPIR--TLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAA 230 +A G+R+N ++ G I T + + P +R E+V + Sbjct: 185 LALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVC 244 Query: 231 FLCSDLSAGISGEVVHVDGGFSI 253 FL S ++ I+G+ V VDGG S+ Sbjct: 245 FLLSPAASFITGQSVDVDGGRSL 267 >2PH3-A nrPDB Length = 245 Score = 203 bits (517), Expect = 6e-53, Method: Composition-based stats. Identities = 53/251 (21%), Positives = 101/251 (40%), Gaps = 14/251 (5%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTY-QNDKLKGRVEEFAAQLGSDIV--LQC 63 ++ L+TG + I IA + +G LA Y QN + V E A + GS +V L Sbjct: 2 RKALITGAS--RGIGRAIALRLAEDGFALAIHYGQNREKAEEVAEEARRRGSPLVAVLGA 59 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 ++ E + + + +V D V++ G L + E ++ + + + Sbjct: 60 NLLEAEAATALVHQAAEVLGGLDTLVNNAGITRDTLL-----VRMKDEDWEAVLEANLSA 114 Query: 124 FVAMAKACRSMLNPG--SALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 + ++ ++ ++ + P +KA L R +A G Sbjct: 115 VFRTTREAVKLMMKARFGRIVNITSVVGILGNPGQANYVASKAGLIGFTRAVAKEYAQRG 174 Query: 182 VRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGIS 241 + VNA++ G I T + +++ P R E+V + AFL S+ + I+ Sbjct: 175 ITVNAVAPGFIETEMTERL--PQEVKEAYLKQIPAGRFGRPEEVAEAVAFLVSEKAGYIT 232 Query: 242 GEVVHVDGGFS 252 G+ + VDGG + Sbjct: 233 GQTLCVDGGLT 243 >2Q2Q-A nrPDB Length = 255 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 56/260 (21%), Positives = 92/260 (35%), Gaps = 21/260 (8%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 L GK LVTG S I GIAQ + R GA + D + E A + Sbjct: 2 LKGKTALVTGSTS--GIGLGIAQVLARAGANIVLNGFGDPAPA-LAEIARHGVKAVHHPA 58 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGF---APGDQLDGDYVNAVTREGFKIAHDIS 120 D+++ A I+ +FA + + D V++ G AP +Q + + + + Sbjct: 59 DLSDVAQIEALFALAEREFGGVDILVNNAGIQHVAPVEQFPLESWDKIIALNLSAVFHGT 118 Query: 121 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 + M ++ ++ + AK + + + Sbjct: 119 RLALPGMR------ARNWGRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGLETATS 172 Query: 181 GVRVNAISAGPIRT---------LAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAF 231 V NAI G + T AA+G + P VT E +G F Sbjct: 173 NVTCNAICPGWVLTPLVQKQIDDRAANGGDPLQAQHDLLAEKQPSLAFVTPEHLGELVLF 232 Query: 232 LCSDLSAGISGEVVHVDGGF 251 LCS+ + + G +VDGG+ Sbjct: 233 LCSEAGSQVRGAAWNVDGGW 252 >5U9P-A nrPDB Length = 265 Score = 202 bits (514), Expect = 1e-52, Method: Composition-based stats. Identities = 55/257 (21%), Positives = 97/257 (37%), Gaps = 14/257 (5%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDI-VL 61 L G+R L+TG S I +A+ + GA + +N++ + G Sbjct: 17 RLDGRRALITG--SGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARRFRDEGFAADHA 74 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGF---APGDQLDGDYVNAVTREGFKIAHD 118 DVAE A + E D V++ G AP D + D +A+ R + Sbjct: 75 VFDVAEHAQVRAAIDEFEARVGAIDILVNNAGIQRRAPLDAFEPDDWHALMRVNLDGVFN 134 Query: 119 ISSYSFVAMAKACRSMLNPG-SALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAM 177 + R M+ G ++ + + +E A P K ++ + M Sbjct: 135 V-------AQAVARHMIARGHGKIINICSVQSELARPTIAPYAATKGAVRMLTKGMCADW 187 Query: 178 GPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLS 237 G++ N ++ G T + D TP R ++++ +A FL S S Sbjct: 188 ARYGIQANGLAPGYFETELNRALVDDAAFSDWLCKRTPAGRWGQVDELCGAAIFLASAAS 247 Query: 238 AGISGEVVHVDGGFSIA 254 ++G+ + VDGG + A Sbjct: 248 DFVNGQTLFVDGGLTSA 264 >4NBV-A nrPDB Length = 246 Score = 201 bits (511), Expect = 3e-52, Method: Composition-based stats. Identities = 54/253 (21%), Positives = 101/253 (39%), Gaps = 12/253 (4%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQND-KLKGRVEEFAAQLGSDIVLQ 62 L G+ ++TG A+ I + AQ +GA + + +++ AA + + Sbjct: 3 LQGRVAIITGAAA--GIGFATAQRFAEDGAIVVLCDVQEARVREAAARLAATGATVSAYR 60 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSY 122 DV +D M A + + D V++ G +L +T F D++ Sbjct: 61 VDVTRRDEVDAMVAAVLAAHQRVDILVNNAGITKDARLAK-----MTEAQFDAVIDVNLK 115 Query: 123 SFVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 A+A ++ +L S + +K + + A +GP+ Sbjct: 116 GVFNCAQAVAGLMTEQGKGVILNASSVVGLYGNFGQTNYAASKFGVIGFTKTWARELGPK 175 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 GVRVNA+ G + T + D K+L + +RR ++ + AFL SD ++ + Sbjct: 176 GVRVNAVCPGFVNTEILQTVPD--KVLDGMTSSCWLRRLAEPAEIASIYAFLASDDASYV 233 Query: 241 SGEVVHVDGGFSI 253 +G + GG S+ Sbjct: 234 NGVAIEASGGMSL 246 >6CI9-A nrPDB Length = 259 Score = 200 bits (510), Expect = 4e-52, Method: Composition-based stats. Identities = 58/248 (23%), Positives = 103/248 (41%), Gaps = 7/248 (2%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN-DKLKGRVEEFAAQLGSDIVLQ 62 L G+ +VTG + I GIA+ G ++ T +N D L V + + G ++ Sbjct: 7 LEGRSAIVTGGSK--GIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVR 64 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSY 122 DV + AE D + G P +L+ + + E + + Sbjct: 65 ADVTDPEDARRTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDI--EQVLGVNFKGTV 122 Query: 123 SFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGV 182 V A + G ++T S G P ++ G +KA+ +R A + P+ + Sbjct: 123 YIVQAALQALTASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAMELAPKKI 182 Query: 183 RVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISG 242 +NA+ G I T + + L + P R ++ D+GN+A F +D +A ++G Sbjct: 183 TINAVLPGNIMTEGLDEMG--QDYLDQMASAIPAGRLGSVADIGNAALFFATDEAAYVTG 240 Query: 243 EVVHVDGG 250 + + VDGG Sbjct: 241 QTLVVDGG 248 >5T5Q-A nrPDB Length = 247 Score = 199 bits (507), Expect = 9e-52, Method: Composition-based stats. Identities = 58/254 (22%), Positives = 104/254 (40%), Gaps = 16/254 (6%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSD---IV 60 + +++TG I IA+ H GA L T D + ++ FAA LGS Sbjct: 7 FENRTLVLTGA--NGGIGRAIAELFHASGANLVLT---DLDREGLDAFAASLGSPERIAT 61 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 ++ D + + A + + D V S G ++ + I+ Sbjct: 62 IKADASSADDAEKTVALAMERFGGIDFLVPSAGIYQAKPFA-----EMSDADWHRTISIN 116 Query: 121 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 + K L S+++TL+ L A R G K ++ + R ++ + P+ Sbjct: 117 LDGVFYLCKRALPALKEDSSIVTLASLAAYRGAYVNAHYGATKGAMVSMTRALSRELAPK 176 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 RVN +S G I T S + + + TP++R ++ + AFLCS ++ + Sbjct: 177 -TRVNGVSPGIIETPMTSEL--LKTRMDETMTQTPLKRLGKPSEIASVIAFLCSPAASFV 233 Query: 241 SGEVVHVDGGFSIA 254 +GE + V+GG +A Sbjct: 234 TGETIQVNGGIYMA 247 >1DOH-A nrPDB Length = 283 Score = 199 bits (506), Expect = 1e-51, Method: Composition-based stats. Identities = 60/264 (22%), Positives = 104/264 (39%), Gaps = 21/264 (7%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN--DKLKGRVEEFAAQLGSDIVL 61 L GK LVTG I +A + R G ++ Y N + + V + Sbjct: 27 LEGKVALVTGA--GRGIGREMAMELGRRGCKVIVNYANSTESAEEVVAAIKKNGSDAACV 84 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 + +V I MF E K++ K D + G + +V VT E F I++ Sbjct: 85 KANVGVVEDIVRMFEEAVKIFGKLDIVCSNSGV-----VSFGHVKDVTPEEFDRVFTINT 139 Query: 122 YSFVAMAKACRSMLNPGSALLTLSYL-GAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 +A+ L G L+ + + G +A+P + V +K ++E R MA M + Sbjct: 140 RGQFFVAREAYKHLEIGGRLILMGSITGQAKAVPKHAVYSGSKGAIETFARCMAIDMADK 199 Query: 181 GVRVNAISAGPIRTLA-----------ASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSA 229 + VN ++ G I+T + + +P+RR D+ Sbjct: 200 KITVNVVAPGGIKTDMYHAVCREYIPNGENLSNEEVDEYAAVQWSPLRRVGLPIDIARVV 259 Query: 230 AFLCSDLSAGISGEVVHVDGGFSI 253 FL S+ ++G+V+ +DGG + Sbjct: 260 CFLASNDGGWVTGKVIGIDGGACM 283 >4IIN-A nrPDB Length = 271 Score = 199 bits (506), Expect = 1e-51, Method: Composition-based stats. Identities = 48/253 (18%), Positives = 104/253 (41%), Gaps = 11/253 (4%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN--DKLKGRVEEFAAQLGSDIVL 61 +GK +L+TG + I IA+ + G ++ Y++ + E + V+ Sbjct: 27 FTGKNVLITGASK--GIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVI 84 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 + D A ++ + + V++ G + T + + + + Sbjct: 85 KFDAASESDFIEAIQTIVQSDGGLSYLVNNAGVVRDKL----AIKMKTEDFHHVIDNNLT 140 Query: 122 YSFVAMAKACRSMLNPG-SALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 +F+ +A + M +++ ++ + ER +K + A + A Sbjct: 141 SAFIGCREALKVMSKSRFGSVVNVASIIGERGNMGQTNYSASKGGMIAMSKSFAYEGALR 200 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 +R N+++ G I T + +KD ++ A P+ R + ++V + AFL SD S+ I Sbjct: 201 NIRFNSVTPGFIETDMNANLKD--ELKADYVKNIPLNRLGSAKEVAEAVAFLLSDHSSYI 258 Query: 241 SGEVVHVDGGFSI 253 +GE + V+GG + Sbjct: 259 TGETLKVNGGLYM 271 >4IIV-A nrPDB Length = 267 Score = 199 bits (506), Expect = 1e-51, Method: Composition-based stats. Identities = 53/250 (21%), Positives = 96/250 (38%), Gaps = 15/250 (6%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKG--RVEEFAAQLGSDIVLQCD 64 + +LVTG + I IA+ + +G + Y D + A G+ +L D Sbjct: 27 RSVLVTGASK--GIGRAIARQLAADGFNIGVHYHRDAAGAQETLNAIVANGGNGRLLSFD 84 Query: 65 VAEDASIDTMFAELGKVWPKFDGFVHSIGFAPG---DQLDGDYVNAVTREGFKIAHDISS 121 VA + + G V + G A L D +AV +++ Sbjct: 85 VANREQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPALSNDDWDAVIHTNLDSFYNVIQ 144 Query: 122 YSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 + M A G ++TLS + AKA + + +A + Sbjct: 145 PCIMPMIGA-----RQGGRIITLSSVSGVMGNRGQVNYSAAKAGIIGATKALAIELAKRK 199 Query: 182 VRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGIS 241 + VN I+ G I T I+ L ++ P++R E+V A++L SD++ ++ Sbjct: 200 ITVNCIAPGLIDTGM---IEMEESALKEAMSMIPMKRMGQAEEVAGLASYLMSDIAGYVT 256 Query: 242 GEVVHVDGGF 251 +V+ ++GG Sbjct: 257 RQVISINGGM 266 >2AE2-A nrPDB Length = 260 Score = 198 bits (504), Expect = 2e-51, Method: Composition-based stats. Identities = 50/255 (19%), Positives = 99/255 (38%), Gaps = 14/255 (5%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDI-VLQ 62 L G LVTG + I YGI + + GA + +N K G + Sbjct: 7 LEGCTALVTGGS--RGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKVEASV 64 Query: 63 CDVAEDASIDTMFAELGKVW-PKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 CD++ + + + + K + V++ G + T E + + I+ Sbjct: 65 CDLSSRSERQELMNTVANHFHGKLNILVNNAGIVIYKE-----AKDYTVEDYSLIMSINF 119 Query: 122 YSFVAMAKACRSMLN--PGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 + ++ L ++ +S + A+P V G K +++ R +A Sbjct: 120 EAAYHLSVLAHPFLKASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAFEWAK 179 Query: 180 EGVRVNAISAGPIRT---LAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDL 236 + +RVN + G I T + ++ L +RR +++ AFLC Sbjct: 180 DNIRVNGVGPGVIATSLVEMTIQDPEQKENLNKLIDRCALRRMGEPKELAAMVAFLCFPA 239 Query: 237 SAGISGEVVHVDGGF 251 ++ ++G++++VDGG Sbjct: 240 ASYVTGQIIYVDGGL 254 >5OVL-A nrPDB Length = 300 Score = 196 bits (500), Expect = 6e-51, Method: Composition-based stats. Identities = 54/250 (21%), Positives = 101/250 (40%), Gaps = 21/250 (8%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVA 66 + +LVTG I IA+ + +G ++A T++ + +QCDV Sbjct: 69 RSVLVTGG--NRGIGLAIARRLAADGHKVAVTHRGSGAPDDL----------FGVQCDVT 116 Query: 67 EDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVA 126 + A++D F E+ + + V + G + L +T E F+ + + Sbjct: 117 DSAAVDRAFKEVEEHQGPVEVLVANAGISKDAFL-----MRMTEERFEEVINTNLTGAFR 171 Query: 127 MAKACRSMLNPG--SALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRV 184 A+ + ++ + + I N AKA L R ++ + GV Sbjct: 172 CAQRASRTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTA 231 Query: 185 NAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEV 244 N ++ G I T + ++ A P +R T E+V + +FL S+ ++ I+G V Sbjct: 232 NVVAPGYIDTEMTRALD--ERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAV 289 Query: 245 VHVDGGFSIA 254 + VDGG + Sbjct: 290 IPVDGGMGMG 299 >3V2G-A nrPDB Length = 271 Score = 196 bits (500), Expect = 6e-51, Method: Composition-based stats. Identities = 57/252 (22%), Positives = 99/252 (39%), Gaps = 13/252 (5%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN--DKLKGRVEEFAAQLGSDIVL 61 L+GK VTG + I IA+ + EGA +A TY N ++ + V E G + + Sbjct: 29 LAGKTAFVTGGS--RGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQAGGRAVAI 86 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 + D + +I+ E + D V+S G L+ T F ++ Sbjct: 87 RADNRDAEAIEQAIRETVEALGGLDILVNSAGIWHSAPLE-----ETTVADFDEVMAVNF 141 Query: 122 YS-FVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 + FVA+ A R + + G + S L P ++ +KA+L + +A +GP Sbjct: 142 RAPFVAIRSASRHLGDGGRIITIGSNLAELVPWPGISLYSASKAALAGLTKGLARDLGPR 201 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 G+ VN + G T D + +D+ A+L + Sbjct: 202 GITVNIVHPGSTDTDMNPADGDHAEA---QRERIATGSYGEPQDIAGLVAWLAGPQGKFV 258 Query: 241 SGEVVHVDGGFS 252 +G + +DGG + Sbjct: 259 TGASLTIDGGAN 270 >1AHH-A nrPDB Length = 255 Score = 196 bits (500), Expect = 6e-51, Method: Composition-based stats. Identities = 65/251 (25%), Positives = 109/251 (43%), Gaps = 12/251 (4%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN-DKLKGRVEEFAAQLGSDIVL 61 L GK ++TG I IA GA + + N D V+E G Sbjct: 8 RLDGKCAIITGA--GAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFAC 65 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 +CD+ + + + K D V++ G D + F+ A++++ Sbjct: 66 RCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD------MPMADFRRAYELNV 119 Query: 122 YSFVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 +SF +++ + N G +LT++ + AE N +KA+ VR MA +G Sbjct: 120 FSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGE 179 Query: 180 EGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAG 239 + +RVN I+ G I T A + + TPIRR +D+ N+A FLCS ++ Sbjct: 180 KNIRVNGIAPGAILTDALKSVITPE-IEQKMLQHTPIRRLGQPQDIANAALFLCSPAASW 238 Query: 240 ISGEVVHVDGG 250 +SG+++ V GG Sbjct: 239 VSGQILTVSGG 249 >4NBT-A nrPDB Length = 240 Score = 194 bits (494), Expect = 3e-50, Method: Composition-based stats. Identities = 49/257 (19%), Positives = 96/257 (37%), Gaps = 21/257 (8%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 60 M L GK ++TG A + IA A EGA++ D + Sbjct: 1 MKKLEGKVAVITGGAK--GLGQAIALAYAEEGAKVIAGDLGD--------LTYSHPNVEG 50 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 + +V + ++ + + + K D V++ G +T + D++ Sbjct: 51 MYLNVTDVTGVEKFYQSVIDKYGKIDILVNNAGITKDAMTRK-----MTEAQWDAVIDVN 105 Query: 121 SYSFVAMAKACRSMLNPGS--ALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMG 178 + + + +++ +S + KA + A Sbjct: 106 LKGVFNLTRLVGPQMQTNGYGSIINISSVVGVFGNIGQANYAATKAGVIGLTMTWAKEFA 165 Query: 179 PEG--VRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDL 236 +G VRVNAI+ G I T + + +L A+T + R E++ A FL SD Sbjct: 166 LKGANVRVNAIAPGYIMTDILKTV--PQDLLDKFAALTMLNRLGQPEEIAKVALFLASDD 223 Query: 237 SAGISGEVVHVDGGFSI 253 ++ ++G+ ++V+GG + Sbjct: 224 ASYVTGQTINVNGGMRL 240 >4Q9N-A nrPDB Length = 298 Score = 194 bits (493), Expect = 3e-50, Method: Composition-based stats. Identities = 75/290 (25%), Positives = 133/290 (45%), Gaps = 38/290 (13%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELA-------------------FTYQNDKL 44 L+GK + G+ +GIA+ + GA + F + Sbjct: 6 LTGKIAFIAGIGDDNGYGWGIAKMLAEAGATILVGTWVPIYKIFSQSLELGKFNASRELS 65 Query: 45 KGRVEEFAAQLGSDIVL--QCDVAED------------ASIDTMFAELGKVWPKFDGFVH 90 G + FA D D+ ++ ++ + ++ K + D VH Sbjct: 66 NGELLTFAKIYPMDASFDTPEDIPQEILENKRYKDLSGYTVSEVVEQVKKHFGHIDILVH 125 Query: 91 SIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAE 150 S+ +P + +R+G+ A SSYSF+++ ++N G++ ++L+YL + Sbjct: 126 SLANSPEIA---KPLLDTSRKGYLAALSTSSYSFISLLSHFGPIMNAGASTISLTYLASM 182 Query: 151 RAIPNYNV-MGLAKASLEANVRYMANAMGPE-GVRVNAISAGPIRTLAASGIKDFRKMLA 208 RA+P Y M AKA+LE++ + +A G GVRVN ISAGP+ + A I +M+ Sbjct: 183 RAVPGYGGGMNAAKAALESDTKVLAWEAGRRWGVRVNTISAGPLASRAGKAIGFIERMVD 242 Query: 209 HCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNE 258 + + P+ + E VG +AAFL S L++ I+GE ++VD G ++ + Sbjct: 243 YYQDWAPLPSPMEAEQVGAAAAFLVSPLASAITGETLYVDHGANVMGIGP 292 >4Z9Y-A nrPDB Length = 253 Score = 194 bits (493), Expect = 4e-50, Method: Composition-based stats. Identities = 46/251 (18%), Positives = 97/251 (38%), Gaps = 11/251 (4%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 L GK L+TG + L I + + G ++ + K +E+ A + L Sbjct: 8 LQGKVALITGCDTGLGQGMAI--GLAQAGCDIVGVNIVEP-KDTIEKVTALGRRFLSLTA 64 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 D++ + + + + D V++ G + + + + +++ S Sbjct: 65 DMSNVSGHAELVEKAVAEFGHVDILVNNAGIIRRE-----DAIEFSEKNWDDVMNLNIKS 119 Query: 124 FVAMAK-ACRSMLN--PGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 M++ R + G ++ ++ + + + +K+++ R MAN Sbjct: 120 VFFMSQTVARQFIKQGKGGKIINIASMLSFQGGIRVPSYTASKSAVMGVTRLMANEWAKH 179 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 G+ VNAI+ G + T ++ + P R +D+ + FL S S I Sbjct: 180 GINVNAIAPGYMATNNTQQLRADEERSKEILDRIPAGRWGLPQDLMGPSVFLASSASDYI 239 Query: 241 SGEVVHVDGGF 251 +G + VDGG+ Sbjct: 240 NGYTIAVDGGW 250 >4K6F-A nrPDB Length = 255 Score = 193 bits (490), Expect = 9e-50, Method: Composition-based stats. Identities = 50/251 (19%), Positives = 91/251 (36%), Gaps = 12/251 (4%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQ--NDKLKGRVEEFAAQLGSDIVLQCD 64 + +VTG L A I ++ G + TY N + E A D Sbjct: 12 RIAVVTGGMGGLGEAVSI--RLNDAGHRVVVTYSPNNTGADRWLTEMHAAGREFHAYPVD 69 Query: 65 VAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSF 124 VA+ S ++ + D V++ G L + + + + S Sbjct: 70 VADHDSCQQCIEKIVRDVGPVDILVNNAGITRDMTLRK-----LDKVNWDAVIRTNLDSV 124 Query: 125 VAMAK-ACRSMLNPG-SALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGV 182 M K C M+ G ++ +S + + AKA + + +A + +GV Sbjct: 125 FNMTKPVCDGMVERGWGRIVNISSVNGSKGSVGQTNYAAAKAGMHGFTKSLALEIARKGV 184 Query: 183 RVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISG 242 VN +S G + T + I + P R E+V A+LCS+ + ++G Sbjct: 185 TVNTVSPGYLATKMVTAIPQDI-LDTKILPQIPAGRLGKPEEVAALVAYLCSEEAGFVTG 243 Query: 243 EVVHVDGGFSI 253 + ++GG + Sbjct: 244 SNIAINGGQHM 254 >3EZL-A nrPDB Length = 256 Score = 192 bits (489), Expect = 1e-49, Method: Composition-based stats. Identities = 52/252 (20%), Positives = 98/252 (38%), Gaps = 13/252 (5%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELA-FTYQNDKLKGRVEEFAAQLGSD-IVLQCD 64 + VTG I I Q +H++G + N + + E LG D + + Sbjct: 14 RIAYVTGGMG--GIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYASEGN 71 Query: 65 VAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSF 124 V + S F ++ + D V++ G +TRE ++ D + S Sbjct: 72 VGDWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRK-----MTREDWQAVIDTNLTSL 126 Query: 125 VAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGV 182 + K + ++ +S + ++ AKA + +A + +GV Sbjct: 127 FNVTKQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVATKGV 186 Query: 183 RVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISG 242 VN +S G I T I+ +L A P+RR + +++G+ A+L S+ S +G Sbjct: 187 TVNTVSPGYIGTDMVKAIRP--DVLEKIVATIPVRRLGSPDEIGSIVAWLASEESGFSTG 244 Query: 243 EVVHVDGGFSIA 254 ++GG + Sbjct: 245 ADFSLNGGLHMG 256 >3U5T-A nrPDB Length = 267 Score = 192 bits (488), Expect = 1e-49, Method: Composition-based stats. Identities = 51/249 (20%), Positives = 96/249 (38%), Gaps = 10/249 (4%) Query: 5 SGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGR--VEEFAAQLGSDIVLQ 62 + K +VTG + I IA + +G + Y + A G + Q Sbjct: 26 TNKVAIVTGAS--RGIGAAIAARLASDGFTVVINYAGKAAAAEEVAGKIEAAGGKALTAQ 83 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSY 122 DV++ A++ +FA + + D V++ G P + F ++ Sbjct: 84 ADVSDPAAVRRLFATAEEAFGGVDVLVNNAGIMPLTT-----IAETGDAVFDRVIAVNLK 138 Query: 123 SFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGV 182 + L G ++ +S P+Y + AKA +EA ++ + + Sbjct: 139 GTFNTLREAAQRLRVGGRIINMSTSQVGLLHPSYGIYAAAKAGVEAMTHVLSKELRGRDI 198 Query: 183 RVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISG 242 VNA++ GP T K ++ + P+ R T +D+ + AFL A ++G Sbjct: 199 TVNAVAPGPTATDLFLEGKSD-EVRDRFAKLAPLERLGTPQDIAGAVAFLAGPDGAWVNG 257 Query: 243 EVVHVDGGF 251 +V+ +GG Sbjct: 258 QVLRANGGI 266 >2CDH-G nrPDB Length = 244 Score = 192 bits (488), Expect = 1e-49, Method: Composition-based stats. Identities = 45/251 (17%), Positives = 90/251 (35%), Gaps = 14/251 (5%) Query: 8 RILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGR--VEEFAAQLGSDIVLQCDV 65 ++VTG + I IA ++ + G ++ Y ++ A G I DV Sbjct: 3 VVVVTGAS--RGIGKAIALSLGKAGCKVLVNYARSAKAAEEVSKQIEAYGGQAITFGGDV 60 Query: 66 AEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFV 125 +++A ++ M W D V++ G L + + + D++ Sbjct: 61 SKEADVEAMMKTAIDAWGTIDVVVNNAGITRDTLL-----IRMKKSQWDEVIDLNLTGVF 115 Query: 126 AMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVR 183 +A ++ ++ ++ + AKA + + A + Sbjct: 116 LCTQAATKIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNIN 175 Query: 184 VNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLC-SDLSAGISG 242 VN + G I + + + M P+ RT E+V FL S ++ I+G Sbjct: 176 VNVVCPGFIASDMTAKLG--EDMEKKILGTIPLGRTGQPENVAGLVEFLALSPAASYITG 233 Query: 243 EVVHVDGGFSI 253 + +DGG +I Sbjct: 234 QAFTIDGGIAI 244 >5OVJ-A nrPDB Length = 256 Score = 192 bits (488), Expect = 2e-49, Method: Composition-based stats. Identities = 54/250 (21%), Positives = 101/250 (40%), Gaps = 21/250 (8%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVA 66 + +LVTG I IA+ + +G ++A T++ + +QCDV Sbjct: 25 RSVLVTGG--NRGIGLAIARRLAADGHKVAVTHRGSGAPDDL----------FGVQCDVT 72 Query: 67 EDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVA 126 + A++D F E+ + + V + G + L +T E F+ + + Sbjct: 73 DSAAVDRAFKEVEEHQGPVEVLVANAGISKDAFL-----MRMTEERFEEVINTNLTGAFR 127 Query: 127 MAKACRSMLNPG--SALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRV 184 A+ + ++ + + I N AKA L R ++ + GV Sbjct: 128 CAQRASRTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTA 187 Query: 185 NAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEV 244 N ++ G I T + ++ A P +R T E+V + +FL S+ ++ I+G V Sbjct: 188 NVVAPGYIDTEMTRALD--ERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAV 245 Query: 245 VHVDGGFSIA 254 + VDGG + Sbjct: 246 IPVDGGMGMG 255 >1GEG-A nrPDB Length = 256 Score = 191 bits (486), Expect = 2e-49, Method: Composition-based stats. Identities = 52/258 (20%), Positives = 92/258 (35%), Gaps = 20/258 (7%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDK-LKGRVEEFAAQLGSDIVLQCDV 65 K LVTG I IA + ++G +A ND K E G + ++ DV Sbjct: 3 KVALVTGA--GQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDV 60 Query: 66 AEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFV 125 ++ + + K FD V++ G AP + ++T E ++I+ + Sbjct: 61 SDRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTP-----IESITPEIVDKVYNINVKGVI 115 Query: 126 AMAKACRSMLNP---GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGV 182 +A G ++ P V +K ++ + A + P G+ Sbjct: 116 WGIQAAVEAFKKEGHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGI 175 Query: 183 RVNAISAGPIRTLAA---------SGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLC 233 VN G ++T + K A + R EDV ++L Sbjct: 176 TVNGYCPGIVKTPMWAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAACVSYLA 235 Query: 234 SDLSAGISGEVVHVDGGF 251 S S ++G+ + +DGG Sbjct: 236 SPDSDYMTGQSLLIDGGM 253 >3OEC-A nrPDB Length = 317 Score = 191 bits (485), Expect = 4e-49, Method: Composition-based stats. Identities = 62/280 (22%), Positives = 108/280 (38%), Gaps = 38/280 (13%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFT-------------YQNDKLKGR 47 M L GK +TG A + + + ++GA++ ++LK Sbjct: 41 MNRLQGKVAFITGAARGQGRTHAV--RLAQDGADIVAIDLCRQQPNLDYAQGSPEELKET 98 Query: 48 VEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNA 107 V Q I Q DV + AS+ + E + D V ++G + + V + Sbjct: 99 VRLVEEQGRRIIARQADVRDLASLQAVVDEALAEFGHIDILVSNVGISNQGE-----VVS 153 Query: 108 VTREGFKIAHDISSYSFVAMAKACRSML---NPGSALLTLSYLGAERAIPNYNVMGLAKA 164 +T + + + +A + G +++ +S R P + +K Sbjct: 154 LTDQQWSDILQTNLIGAWHACRAVLPSMIERGQGGSVIFVSSTVGLRGAPGQSHYAASKH 213 Query: 165 SLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVT---------- 214 ++ + +AN +G +RVN+++ G + T A K + L H E T Sbjct: 214 GVQGLMLSLANEVGRHNIRVNSVNPGAVNTEMALNEKLLKMFLPHLENPTREDAAELFSQ 273 Query: 215 ----PIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGG 250 PI V EDV N+ A+L SD + I G + VDGG Sbjct: 274 LTLLPIP-WVEPEDVSNAVAWLASDEARYIHGAAIPVDGG 312 >2NTV-A nrPDB Length = 268 Score = 190 bits (484), Expect = 4e-49, Method: Composition-based stats. Identities = 82/266 (30%), Positives = 131/266 (49%), Gaps = 18/266 (6%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDI-V 60 G L GKRILV+G+ + SIA+ IA+ GA+L T D+L+ ++ A +L + Sbjct: 2 GLLEGKRILVSGIITDSSIAFHIAKVAQEAGAQLVLTG-FDRLR-LIQRIADRLPDKAPL 59 Query: 61 LQCDVAEDASIDTMFAELGKVWP---KFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAH 117 ++ DV + + T+ + K DG VHSIGF P + + E Sbjct: 60 IELDVQNEEHLATLAERVTAEIGEGNKLDGVVHSIGFMPQTGMGTNQFFDAPYEDVSKGI 119 Query: 118 DISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAM 177 IS+YS+ ++AKA ++N G +++ + + RA+P YN M +AK++LE+ R++A Sbjct: 120 HISTYSYASLAKALLLIMNSGGSIVGMDF-DPTRAMPAYNWMTVAKSALESVNRFVAREA 178 Query: 178 GPEGVRVNAISAGPIRTLAASGI----------KDFRKMLAHCEAVTPIR-RTVTIEDVG 226 G GVR N ++AGPIRTLA S I + + + PI V Sbjct: 179 GKYGVRSNLVAAGPIRTLAMSAIVGGAFGEEAGAQMQLLEEGWDQRAPIGWNMKDPTPVA 238 Query: 227 NSAAFLCSDLSAGISGEVVHVDGGFS 252 + L S+ +G +++ DGG S Sbjct: 239 KTVCALLSEWLPATTGSIIYADGGAS 264 >4CQM-B nrPDB Length = 244 Score = 190 bits (483), Expect = 6e-49, Method: Composition-based stats. Identities = 57/241 (23%), Positives = 98/241 (40%), Gaps = 14/241 (5%) Query: 15 ASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTM 74 I +AQ M R+G LA +N L+G G + CDVA++ + Sbjct: 16 GGSRGIGRAVAQLMARKGYRLAVIARN--LEGAKAAAGDLGGDHLAFSCDVAKEHDVQNT 73 Query: 75 FAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSM 134 F EL K + + V++ G DG V T + H S + A R+M Sbjct: 74 FEELEKHLGRVNFLVNAAGINR----DGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 129 Query: 135 LNP-GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIR 193 + G +++ + + + +V +K L R +A + + +RVN ++ G + Sbjct: 130 IQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH 189 Query: 194 TLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSI 253 T +K+ H + P+ R +V ++ FL S I+G V+ VDGG + Sbjct: 190 TDMTKDLKE-----EHLKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGLQL 242 Query: 254 A 254 Sbjct: 243 I 243 >5YSS-A nrPDB Length = 256 Score = 189 bits (481), Expect = 1e-48, Method: Composition-based stats. Identities = 58/260 (22%), Positives = 96/260 (36%), Gaps = 21/260 (8%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 L+GK LVTG S I GIAQ + + GA L D + + A + Sbjct: 3 LTGKTALVTGSTS--GIGLGIAQVLAQAGATLILNGFGDVDAAK-DAVAQYGKTPGYHGA 59 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGF---APGDQLDGDYVNAVTREGFKIAHDIS 120 D++++A I M + D +++ G +P + D NA+ + Sbjct: 60 DLSDEAQIADMMRYAESEFGGVDILINNAGIQHVSPIETFPVDKWNAIIAINLSSVFHTT 119 Query: 121 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 + M ++ ++ + A + AK + + +A Sbjct: 120 RLALPGMR------ARNWGRIINIASVHGLVASKEKSAYVAAKHGVVGLTKTIALETAQT 173 Query: 181 GVRVNAISAGPIRT---------LAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAF 231 + NA+ G + T A G + A P R VT E +GN A F Sbjct: 174 EITCNALCPGWVLTPLVQQQIDKRIAEGAEPEAARDALLAEKQPSREFVTPEQLGNLALF 233 Query: 232 LCSDLSAGISGEVVHVDGGF 251 LCSD +A + G ++DGG+ Sbjct: 234 LCSDGAAQVRGVAWNMDGGW 253 >3UF0-A nrPDB Length = 273 Score = 189 bits (480), Expect = 1e-48, Method: Composition-based stats. Identities = 62/251 (24%), Positives = 108/251 (43%), Gaps = 12/251 (4%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 L+G+ +VTG S I IA R GA + + D +K +E A GS + Sbjct: 29 LAGRTAVVTGAGS--GIGRAIAHGYARAGAHVLAWGRTDGVKEVADEIADGGGSAEAVVA 86 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGF---APGDQLDGDYVNAVTREGFKIAHDIS 120 D+A+ + EL + D V++ G AP +++ V A +S Sbjct: 87 DLADLEGAANVAEELAAT-RRVDVLVNNAGIIARAPAEEVSLGRWREVLTVNLDAAWVLS 145 Query: 121 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 AM + + ++T++ + + + N +K ++ R +A+ Sbjct: 146 RSFGTAM------LAHGSGRIVTIASMLSFQGGRNVAAYAASKHAVVGLTRALASEWAGR 199 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 GV VNA++ G + T + ++ + A A P R T ED+ A FL SD ++ + Sbjct: 200 GVGVNALAPGYVVTANTAALRADDERAAEITARIPAGRWATPEDMVGPAVFLASDAASYV 259 Query: 241 SGEVVHVDGGF 251 G+V+ VDGG+ Sbjct: 260 HGQVLAVDGGW 270 >1K2W-A nrPDB Length = 256 Score = 188 bits (479), Expect = 2e-48, Method: Composition-based stats. Identities = 61/261 (23%), Positives = 97/261 (37%), Gaps = 23/261 (8%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN-DKLKGRVEEFAAQLGSDIVL 61 L GK L+TG A I A+A REGA +A N + + E + + Sbjct: 2 RLDGKTALITGSA--RGIGRAFAEAYVREGARVAIADINLEAARATAAEI---GPAACAI 56 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 DV + ASID AEL W D V++ D + +TRE + I+ Sbjct: 57 ALDVTDQASIDRCVAELLDRWGSIDILVNNAAL-----FDLAPIVEITRESYDRLFAINV 111 Query: 122 YSFVAMAKACRSML---NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMG 178 + M +A + G ++ ++ R V KA++ + + + Sbjct: 112 SGTLFMMQAVARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNLI 171 Query: 179 PEGVRVNAISAGPIRTLAASGIK---------DFRKMLAHCEAVTPIRRTVTIEDVGNSA 229 G+ VNAI+ G + G+ + A P R ED+ A Sbjct: 172 RHGINVNAIAPGVVDGEHWDGVDAKFADYENLPRGEKKRQVGAAVPFGRMGRAEDLTGMA 231 Query: 230 AFLCSDLSAGISGEVVHVDGG 250 FL + + I + +VDGG Sbjct: 232 IFLATPEADYIVAQTYNVDGG 252 >3D3W-A nrPDB Length = 244 Score = 188 bits (479), Expect = 2e-48, Method: Composition-based stats. Identities = 56/252 (22%), Positives = 109/252 (43%), Gaps = 17/252 (6%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQ 62 FL+G+R+LVTG I G QA+H GA + + + ++ + + Sbjct: 4 FLAGRRVLVTGAGK--GIGRGTVQALHATGARVV---AVSRTQADLDSLVRECPGIEPVC 58 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSY 122 D+ + + + + D V++ A VT+E F + +++ Sbjct: 59 VDLGDWEATERALGSV----GPVDLLVNNAAVALLQPF-----LEVTKEAFDRSFEVNLR 109 Query: 123 SFVAMAK-ACRSMLNPG--SALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 + + +++ R ++ G A++ +S ++RA+ N++V K +L+ + MA +GP Sbjct: 110 AVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGP 169 Query: 180 EGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAG 239 +RVNA++ + T P+ + +E V N+ FL SD S Sbjct: 170 HKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGM 229 Query: 240 ISGEVVHVDGGF 251 +G + V+GGF Sbjct: 230 TTGSTLPVEGGF 241 >3WYE-A nrPDB Length = 256 Score = 188 bits (479), Expect = 2e-48, Method: Composition-based stats. Identities = 55/258 (21%), Positives = 95/258 (36%), Gaps = 20/258 (7%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDK-LKGRVEEFAAQLGSDIVLQCDV 65 K LVTG I IA + ++G +A ND K E G + ++ DV Sbjct: 3 KVALVTGA--GQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDV 60 Query: 66 AEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS-F 124 ++ + + K FD V++ G A L VT E K + ++ +S F Sbjct: 61 SDRDQVFAAVEQARKTLGGFDVIVNNAGIAQIKPL-----LEVTEEDLKQIYSVNVFSVF 115 Query: 125 VAMAKACRSMLN--PGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGV 182 + A + G ++ + + A + P + K ++ + A + P G+ Sbjct: 116 FGIQAAVEAFKKEGHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAARDLAPLGI 175 Query: 183 RVNAISAGPIRTLAASGIK---------DFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLC 233 VN G + T I + + + R EDV +FL Sbjct: 176 TVNGYCPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLA 235 Query: 234 SDLSAGISGEVVHVDGGF 251 S S ++G+ + +DGG Sbjct: 236 SPDSDYMTGQSLLIDGGM 253 >1ENP-A nrPDB Length = 312 Score = 188 bits (478), Expect = 2e-48, Method: Composition-based stats. Identities = 84/289 (29%), Positives = 139/289 (48%), Gaps = 38/289 (13%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAF---------------TYQNDKLK--- 45 L GKR + G+A + +A+++ GAE+ + D+ + Sbjct: 16 LRGKRAFIAGIADDNGYGWAVAKSLAAAGAEILVGTWVPALNIFETSLRRGKFDQSRVLP 75 Query: 46 -GRVEEFAAQLGSDIVL--QCDVAEDA------------SIDTMFAELGKVWPKFDGFVH 90 G + E D V DV ED ++ + + + D VH Sbjct: 76 DGSLMEIKKVYPLDAVFDNPEDVPEDVKANKRYAGSSNWTVQEAAECVRQDFGSIDILVH 135 Query: 91 SIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAE 150 S A G ++ + +R+G+ A SSYSFV++ ++NPG A ++L+Y+ +E Sbjct: 136 S--LANGPEVSKPLLE-TSRKGYLAAISASSYSFVSLLSHFLPIMNPGGASISLTYIASE 192 Query: 151 RAIPNY-NVMGLAKASLEANVRYMANAMG-PEGVRVNAISAGPIRTLAASGIKDFRKMLA 208 R IP Y M AKA+LE++ R +A G + +RVN ISAGP+ + AA I M+ Sbjct: 193 RIIPGYGGGMSSAKAALESDTRVLAFEAGRKQNIRVNTISAGPLGSRAAKAIGFIDTMIE 252 Query: 209 HCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMN 257 + PI++T+T ++VGN+AAFL S L++ I+G ++VD G + + Sbjct: 253 YSYNNAPIQKTLTADEVGNAAAFLVSPLASAITGATIYVDNGLNSMGVA 301 >2O2S-A nrPDB Length = 315 Score = 188 bits (478), Expect = 2e-48, Method: Composition-based stats. Identities = 84/293 (28%), Positives = 135/293 (46%), Gaps = 44/293 (15%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAF---------------TYQNDKLKGRV 48 L G+ V GVA + IA+ + GA +A + + D+ + Sbjct: 7 LRGQTAFVAGVADSHGYGWAIAKHLASAGARVALGTWPPVLGLFQKSLQSGRLDEDRKLP 66 Query: 49 E----EFAAQLGSDIV------LQCDVAEDA--------SIDTMFAELGKVWPKFDGFVH 90 + EFA D + D+ ++ +I + ++ + D VH Sbjct: 67 DGSLIEFAGVYPLDAAFDKPEDVPQDIKDNKRYAGVDGYTIKEVAVKVKQDLGNIDILVH 126 Query: 91 SIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAE 150 S A G ++ + +R+G+ A S+YSFV++ + ++N G + +TLSYL AE Sbjct: 127 S--LANGPEVTKPLLE-TSRKGYLAASSNSAYSFVSLLQHFGPIMNEGGSAVTLSYLAAE 183 Query: 151 RAIPNYNV-MGLAKASLEANVRYMANAMG-PEGVRVNAISAGPIRTLAASGI------KD 202 R +P Y M AKA+LE++ R +A G GVRVNAISAGP+++ AAS I Sbjct: 184 RVVPGYGGGMSSAKAALESDTRTLAWEAGQKYGVRVNAISAGPLKSRAASAIGKSGEKSF 243 Query: 203 FRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAA 255 + + P+RR + +DVG +A FL S L+ +SG ++VD G Sbjct: 244 IDYAIDYSYNNAPLRRDLHSDDVGGAALFLLSPLARAVSGVTLYVDNGLHAMG 296 >1O5I-A nrPDB Length = 249 Score = 187 bits (476), Expect = 4e-48, Method: Composition-based stats. Identities = 54/250 (21%), Positives = 108/250 (43%), Gaps = 24/250 (9%) Query: 5 SGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCD 64 K +LV +A+ I +A + +EGAE+ +N+ E + G V+ CD Sbjct: 18 RDKGVLV--LAASRGIGRAVADVLSQEGAEVTICARNE-------ELLKRSGHRYVV-CD 67 Query: 65 VAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSF 124 + + +D +F ++ + D V + G + + +T E FK A D + Sbjct: 68 LRK--DLDLLFEKVKE----VDILVLNAG-----GPKAGFFDELTNEDFKEAIDSLFLNM 116 Query: 125 VAMAKACRSMLNP--GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGV 182 + + + + ++ ++ I N A+ +L ++ ++ + P G+ Sbjct: 117 IKIVRNYLPAMKEKGWGRIVAITSFSVISPIENLYTSNSARMALTGFLKTLSFEVAPYGI 176 Query: 183 RVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISG 242 VN ++ G T + K E+ P+RR E++ + AFLCS+ ++ ++G Sbjct: 177 TVNCVAPGWTETERVKELLSEEKK-KQVESQIPMRRMAKPEEIASVVAFLCSEKASYLTG 235 Query: 243 EVVHVDGGFS 252 + + VDGG S Sbjct: 236 QTIVVDGGLS 245 >4OYR-A nrPDB Length = 289 Score = 187 bits (475), Expect = 5e-48, Method: Composition-based stats. Identities = 84/268 (31%), Positives = 134/268 (50%), Gaps = 22/268 (8%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDI-V 60 G L GKRILV+G+ + SIA+ IA+ +GA+L T D+L+ ++ +L + + Sbjct: 23 GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTG-FDRLR-LIQRITDRLPAKAPL 80 Query: 61 LQCDVAEDASIDTM---FAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAH 117 L+ DV + + ++ E K DG VHSIGF P + + Sbjct: 81 LELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGI 140 Query: 118 DISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAM 177 IS+YS+ +MAKA ++NPG +++ + + RA+P YN M +AK++LE+ R++A Sbjct: 141 HISAYSYASMAKALLPIMNPGGSIVGMDF-DPSRAMPAYNWMTVAKSALESVNRFVAREA 199 Query: 178 GPEGVRVNAISAGPIRTLAASGI----------KDFRKMLAHCEAVTPIR---RTVTIED 224 G GVR N ++AGPIRTLA S I + + + PI + T Sbjct: 200 GKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATP-- 257 Query: 225 VGNSAAFLCSDLSAGISGEVVHVDGGFS 252 V + L SD +G++++ DGG Sbjct: 258 VAKTVCALLSDWLPATTGDIIYADGGAH 285 >5OJG-A nrPDB Length = 260 Score = 186 bits (474), Expect = 6e-48, Method: Composition-based stats. Identities = 55/256 (21%), Positives = 106/256 (41%), Gaps = 15/256 (5%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV-- 60 GK +VT A+ I IA+ + EGA + +N K E+ G V Sbjct: 7 RFEGKVAIVT--AATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAG 64 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 + +A + + + K + V++ G P ++ V+ + + +++ Sbjct: 65 IAGHIASTDDQKKLVDFTLQKFGKINILVNNHGINPA----FGHILEVSDQVWDKLFEVN 120 Query: 121 SYSFVAMAKACRSMLNP--GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMG 178 + M K + G A++ + A ++ P G+ K +L R +A + Sbjct: 121 VKAGFQMTKLVHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLA 180 Query: 179 PEGVRVNAISAGPIRTLAASGIK----DFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCS 234 + +RVN I+ G I+T + + D K L + + + R +D + A+L S Sbjct: 181 KDNIRVNGIAPGVIKTKMSQVLWDGGEDAEKELTDIQEIA-LGRLGVPDDCAGTVAYLAS 239 Query: 235 DLSAGISGEVVHVDGG 250 D S+ I+GE++ + GG Sbjct: 240 DDSSYITGEMIIIAGG 255 >3VZS-A nrPDB Length = 257 Score = 186 bits (473), Expect = 8e-48, Method: Composition-based stats. Identities = 52/252 (20%), Positives = 97/252 (38%), Gaps = 13/252 (5%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELA-FTYQNDKLKGRVEEFAAQLGSD-IVLQCD 64 + VTG I I Q + ++G + N + + E LG D I + + Sbjct: 15 RIAYVTGGMG--GIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGN 72 Query: 65 VAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSF 124 VA+ S T F ++ + D +++ G +TR + D + S Sbjct: 73 VADWDSTKTAFDKVKSEVGEVDVLINNAGITRDVVFRK-----MTRADWDAVIDTNLTSL 127 Query: 125 VAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGV 182 + K + ++ +S + ++ AKA L +A + +GV Sbjct: 128 FNVTKQVIDGMADRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGV 187 Query: 183 RVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISG 242 VN +S G I T I+ + +L A P++R E++ + A+L S+ S +G Sbjct: 188 TVNTVSPGYIATDMVKAIR--QDVLDKIVATIPVKRLGLPEEIASICAWLSSEESGFSTG 245 Query: 243 EVVHVDGGFSIA 254 ++GG + Sbjct: 246 ADFSLNGGLHMG 257 >1HXH-A nrPDB Length = 253 Score = 186 bits (473), Expect = 8e-48, Method: Composition-based stats. Identities = 66/264 (25%), Positives = 115/264 (43%), Gaps = 21/264 (7%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLG-SDIV 60 L GK LVTG AS + + + + EGA++AF+ N+ ++ AA+LG + Sbjct: 2 NRLQGKVALVTGGAS--GVGLEVVKLLLGEGAKVAFSDINEAAG---QQLAAELGERSMF 56 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFA-PGDQLDGDYVNAVTREGFKIAHDI 119 ++ DV+ +A + A + + + V++ G PGD G E F I Sbjct: 57 VRHDVSSEADWTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRL------EDFSRLLKI 110 Query: 120 SSYS-FVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMG 178 ++ S F+ + +M G +++ ++ + + I Y +KA++ A R A + Sbjct: 111 NTESVFIGCQQGIAAMKETGGSIINMASVSSWLPIEQYAGYSASKAAVSALTRAAALSCR 170 Query: 179 PEG--VRVNAISAGPIRTLAASGIKDF---RKMLAHCEAVTPIRRTVTIEDVGNSAAFLC 233 +G +RVN+I I T ++M+ H + R E + FL Sbjct: 171 KQGYAIRVNSIHPDGIYTPMMQASLPKGVSKEMVLHDPKLNRAGRAYMPERIAQLVLFLA 230 Query: 234 SDLSAGISGEVVHVDGGFSIAAMN 257 SD S+ +SG +H D SI M Sbjct: 231 SDESSVMSGSELHADN--SILGMG 252 >3A28-C nrPDB Length = 258 Score = 185 bits (471), Expect = 1e-47, Method: Composition-based stats. Identities = 58/260 (22%), Positives = 104/260 (40%), Gaps = 22/260 (8%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTY---QNDKLKGRVEEFAAQLGSDIVLQC 63 K +VTG A I GI++ + +G ++A Q ++ ++ A + + Sbjct: 3 KVAMVTGGAQ--GIGRGISEKLAADGFDIAVADLPQQEEQAAETIKLIEAADQKAVFVGL 60 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 DV + A+ D+ E + FD V++ G A L VT E K + ++ +S Sbjct: 61 DVTDKANFDSAIDEAAEKLGGFDVLVNNAGIAQIKPL-----LEVTEEDLKQIYSVNVFS 115 Query: 124 -FVAMAKACRSMLNPG--SALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 F + A R G ++ + + A + P + K ++ + A + P+ Sbjct: 116 VFFGIQAASRKFDELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQELAPK 175 Query: 181 GVRVNAISAGPIRTLAASGIK---------DFRKMLAHCEAVTPIRRTVTIEDVGNSAAF 231 G VNA + G + T I + + + R EDV +F Sbjct: 176 GHTVNAYAPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSF 235 Query: 232 LCSDLSAGISGEVVHVDGGF 251 L S+ S ++G+V+ VDGG Sbjct: 236 LASENSNYVTGQVMLVDGGM 255 >3RWB-A nrPDB Length = 247 Score = 185 bits (471), Expect = 1e-47, Method: Composition-based stats. Identities = 48/252 (19%), Positives = 98/252 (38%), Gaps = 13/252 (5%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQ 62 L+GK LVTG A I IA + +GA + + N + A+ + Sbjct: 3 RLAGKTALVTGAAQ--GIGKAIAARLAADGATVIVSDINAEGAKAAA--ASIGKKARAIA 58 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSY 122 D+++ S+ +FAE+ + D V++ P + V + ++ D++ Sbjct: 59 ADISDPGSVKALFAEIQALTGGIDILVNNASIVPFVA-----WDDVDLDHWRKIIDVNLT 113 Query: 123 SFVAMAKACRSMLN---PGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 + +A + +++++ PN AK + R +A +G Sbjct: 114 GTFIVTRAGTDQMRAAGKAGRVISIASNTFFAGTPNMAAYVAAKGGVIGFTRALATELGK 173 Query: 180 EGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAG 239 + NA++ G I + + E + ++ E + + +FL SD + Sbjct: 174 YNITANAVTPGLIESDGVKA-SPHNEAFGFVEMLQAMKGKGQPEHIADVVSFLASDDARW 232 Query: 240 ISGEVVHVDGGF 251 I+G+ ++VD G Sbjct: 233 ITGQTLNVDAGM 244 >4AVY-A nrPDB Length = 242 Score = 185 bits (469), Expect = 2e-47, Method: Composition-based stats. Identities = 56/248 (22%), Positives = 105/248 (42%), Gaps = 19/248 (7%) Query: 5 SGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCD 64 +G+++LVTG +S I IA GAE+ + A + + D Sbjct: 10 AGQQVLVTGGSS--GIGAAIAMQFAELGAEVVALGLDADGVH-----APRHPRIRREELD 62 Query: 65 VAEDASIDTMFAELGKVWPKFDGFVHSIGFAPG-DQLDGDYVNAVTREGFKIAHDISSYS 123 + + + +F + P+ D V++ G + ++ D V R A S + Sbjct: 63 ITDSQRLQRLF----EALPRLDVLVNNAGISRDREEYDLATFERVLRLNLSAAMLASQLA 118 Query: 124 FVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVR 183 +A+ G ++L ++ + + + +K ++ R +A E +R Sbjct: 119 RPLLAQ-------RGGSILNIASMYSTFGSADRPAYSASKGAIVQLTRSLACEYAAERIR 171 Query: 184 VNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGE 243 VNAI+ G I T +G+K + TP+ R +V ++AAFLC ++ ++G Sbjct: 172 VNAIAPGWIDTPLGAGLKADVEATRRIMQRTPLARWGEAPEVASAAAFLCGPGASFVTGA 231 Query: 244 VVHVDGGF 251 V+ VDGG+ Sbjct: 232 VLAVDGGY 239 >1UZM-A nrPDB Length = 247 Score = 185 bits (469), Expect = 3e-47, Method: Composition-based stats. Identities = 47/250 (18%), Positives = 96/250 (38%), Gaps = 21/250 (8%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVA 66 + +LVTG I IAQ + +G ++A T++ + ++ DV Sbjct: 16 RSVLVTGG--NRGIGLAIAQRLAADGHKVAVTHRGSGAPKGL----------FGVEVDVT 63 Query: 67 EDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVA 126 + ++D F + + + V + G + ++ +T E F+ + + Sbjct: 64 DSDAVDRAFTAVEEHQGPVEVLVSNAGLSAD-----AFLMRMTEEKFEKVINANLTGAFR 118 Query: 127 MAKACRSMLNPG--SALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRV 184 +A+ + ++ + + I N +KA + R +A + V Sbjct: 119 VAQRASRSMQRNKFGRMIFIGSVSGLWGIGNQANYAASKAGVIGMARSIARELSKANVTA 178 Query: 185 NAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEV 244 N ++ G I T + ++ P +R T +V +FL S+ ++ ISG V Sbjct: 179 NVVAPGYIDTDMTRALD--ERIQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISGAV 236 Query: 245 VHVDGGFSIA 254 + VDGG + Sbjct: 237 IPVDGGMGMG 246 >4KMS-A nrPDB Length = 249 Score = 184 bits (468), Expect = 3e-47, Method: Composition-based stats. Identities = 41/249 (16%), Positives = 94/249 (37%), Gaps = 15/249 (6%) Query: 9 ILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAED 68 +VTG I A + +G + + ++ + E + + +VA+ Sbjct: 13 AIVTGGT--RGIGKATALELKNKGLTVVANFFSNYDAAKEMEEKYGIKTKC---WNVADF 67 Query: 69 ASIDTMFAELGKVWPK-FDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAM 127 E+ + + K V++ G L + ++ + + +++ S M Sbjct: 68 EECRQAVKEIEEEFKKPVSILVNNAGITKDKML-----HRMSHQDWNDVINVNLNSCFNM 122 Query: 128 AKACRSMLNPG--SALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVN 185 + + + ++ +S + A+ AKA + + +A + + VN Sbjct: 123 SSSVMEQMRNQDYGRIVNISSINAQAGQVGQTNYSAAKAGIIGFTKALARETASKNITVN 182 Query: 186 AISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVV 245 I+ G I T + +LA P +R E++ + AFL + + I+GE + Sbjct: 183 CIAPGYIATEMVGAV--PEDVLAKIINSIPKKRLGQPEEIARAVAFLVDENAGFITGETI 240 Query: 246 HVDGGFSIA 254 ++GG ++ Sbjct: 241 SINGGHNMI 249 >5VT6-A nrPDB Length = 269 Score = 182 bits (463), Expect = 1e-46, Method: Composition-based stats. Identities = 44/252 (17%), Positives = 91/252 (36%), Gaps = 14/252 (5%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTY--QNDKLKGRVEEFAAQLGSDIVLQCD 64 + VTG + I++ +H G +A ++ +ND + + D Sbjct: 26 RVAFVTGGMG--GLGAAISRRLHDAGMAVAVSHSERNDHVSTWLMHERDAGRDFKAYAVD 83 Query: 65 VAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQ---LDGDYVNAVTREGFKIAHDISS 121 VA+ S + ++ + K D +++ G + +AV R +++ Sbjct: 84 VADFESCERCAEKVLADFGKVDVLINNAGITRDATFMKMTKGDWDAVMRTDLDAMFNVTK 143 Query: 122 YSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 M + ++ + + R AKA + + +A G Sbjct: 144 QFIAGMVE------RRFGRIVNIGSVNGSRGAFGQANYASAKAGIHGFTKTLALETAKRG 197 Query: 182 VRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGIS 241 + VN +S G + T + + A P+ R ++V AFLCSD + ++ Sbjct: 198 ITVNTVSPGYLATAMVEAVPQDV-LEAKILPQIPVGRLGRPDEVAALIAFLCSDDAGFVT 256 Query: 242 GEVVHVDGGFSI 253 G + ++GG + Sbjct: 257 GADLAINGGMHM 268 >3W8F-A nrPDB Length = 260 Score = 181 bits (461), Expect = 2e-46, Method: Composition-based stats. Identities = 53/266 (19%), Positives = 96/266 (36%), Gaps = 24/266 (9%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN---DKLKGRVEEFAAQLGSDI 59 L GK+ +VTG S I +A + + GA++ D + R + Sbjct: 1 MLKGKKAVVTGSTS--GIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVKAY 58 Query: 60 VLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGF---APGDQLDGDYVNAVTREGFKIA 116 L D+++ + A+ + D V++ G AP ++ D NA+ Sbjct: 59 YLNADLSDAQATRDFIAKAAEALGGLDILVNNAGIQHTAPIEEFPVDKWNAIIALNLSAV 118 Query: 117 HDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANA 176 ++ + M K ++ ++ A N + AK + + A Sbjct: 119 FHGTAAALPIMQK------QGWGRIINIASAHGLVASVNKSAYVAAKHGVVGLTKVTALE 172 Query: 177 MGPEGVRVNAISAGPIRTL----------AASGIKDFRKMLAHCEAVTPIRRTVTIEDVG 226 +G+ NAI G +RT GI P + VT E +G Sbjct: 173 NAGKGITCNAICPGWVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQPSLQFVTPEQLG 232 Query: 227 NSAAFLCSDLSAGISGEVVHVDGGFS 252 +A FL S + ++G + +DGG++ Sbjct: 233 GAAVFLSSAAADQMTGTTLSLDGGWT 258 >4E6P-A nrPDB Length = 259 Score = 181 bits (459), Expect = 3e-46, Method: Composition-based stats. Identities = 59/263 (22%), Positives = 96/263 (36%), Gaps = 23/263 (8%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN-DKLKGRVEEFAAQLGSDI 59 M L GK L+TG A I A+A REGA +A + ++ + E + Sbjct: 3 MKRLEGKSALITGSA--RGIGRAFAEAYVREGATVAIADIDIERARQAAAEI---GPAAY 57 Query: 60 VLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDI 119 +Q DV SID A + D V++ D + +TRE ++ I Sbjct: 58 AVQMDVTRQDSIDAAIAATVEHAGGLDILVNNAAL-----FDLAPIVEITRESYEKLFAI 112 Query: 120 SSYS-FVAMAKACRSMLN--PGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANA 176 + + A R M+ G ++ ++ R + KA++ + + Sbjct: 113 NVAGTLFTLQAAARQMIAQGRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAGLD 172 Query: 177 MGPEGVRVNAISAGPIRTLAASGIKDFRKMLAH---------CEAVTPIRRTVTIEDVGN 227 + + VNAI+ G + G+ + P R T ED+ Sbjct: 173 LIKHRINVNAIAPGVVDGEHWDGVDALFARYENRPRGEKKRLVGEAVPFGRMGTAEDLTG 232 Query: 228 SAAFLCSDLSAGISGEVVHVDGG 250 A FL S S I + +VDGG Sbjct: 233 MAIFLASAESDYIVSQTYNVDGG 255 >5JY1-A nrPDB Length = 274 Score = 180 bits (457), Expect = 6e-46, Method: Composition-based stats. Identities = 57/262 (21%), Positives = 99/262 (37%), Gaps = 10/262 (3%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVE-EFAAQLGSDI 59 MG L + LVTG + ++ EGA + N+ +VE E G + Sbjct: 9 MGLLEQRVALVTGAGGGIGRGVA--RSFGNEGAAVIIAEINESTGRQVEQEIREMGGRSL 66 Query: 60 VLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDI 119 ++ DV ASI+ + + D V++ F P + + T E + Sbjct: 67 FVKTDVTSKASIEAAVRSAVEQFGSLDILVNNA-FVPTPNV---LLEEKTDEMLEQTLTT 122 Query: 120 SSYSFVAMAKACRSMLN--PGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAM 177 S ++ +A + ++ + E + AKA + R A+ Sbjct: 123 SLWATWWAMRAAFVPMRERRWGRIVNFYSIDTETGAWLHGDYNTAKAGIVGLTRSAASEW 182 Query: 178 GPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIE-DVGNSAAFLCSDL 236 G + VNAI+ + + A P+ R+ E D+G +A F S++ Sbjct: 183 GRFNITVNAIAPTAMGATFFELAAKNPEFAERSAAARPLGRSGDPEQDIGPAAVFFASEM 242 Query: 237 SAGISGEVVHVDGGFSIAAMNE 258 S ++GE +HVDGG + N Sbjct: 243 SRFVTGETLHVDGGLHLPGYNS 264 >3V2H-A nrPDB Length = 281 Score = 179 bits (454), Expect = 1e-45, Method: Composition-based stats. Identities = 50/262 (19%), Positives = 100/262 (38%), Gaps = 24/262 (9%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN--DKLKGRVEEFAA-QLGSDIVLQC 63 K ++TG S I IA+ + + GA + D+++ +E A G+ + Sbjct: 26 KTAVITGSTS--GIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAGLSSGTVLHHPA 83 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGF---APGDQLDGDYVNAVTREGFKIAHDIS 120 D+ + + I M A + + D V++ G + + + + + Sbjct: 84 DMTKPSEIADMMAMVADRFGGADILVNNAGVQFVEKIEDFPVEQWDRIIAVNLSSSFHTI 143 Query: 121 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 + M K ++ ++ A P + AK + + +A + Sbjct: 144 RGAIPPMKK------KGWGRIINIASAHGLVASPFKSAYVAAKHGIMGLTKTVALEVAES 197 Query: 181 GVRVNAISAGPIRTLA----------ASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAA 230 GV VN+I G + T GI + + + P ++ +T+E V + A Sbjct: 198 GVTVNSICPGYVLTPLVEKQIPDQARTRGITEEQVINEVMLKGQPTKKFITVEQVASLAL 257 Query: 231 FLCSDLSAGISGEVVHVDGGFS 252 +L D +A I+G V +DGG++ Sbjct: 258 YLAGDDAAQITGTHVSMDGGWT 279 >4HP8-A nrPDB Length = 247 Score = 178 bits (453), Expect = 2e-45, Method: Composition-based stats. Identities = 51/251 (20%), Positives = 93/251 (37%), Gaps = 16/251 (6%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 L G++ LVTG + IA + GAE+ + ++ A G+ L Sbjct: 7 LEGRKALVTGA--NTGLGQAIAVGLAAAGAEVVCAARRAP-DETLDIIAKDGGNASALLI 63 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 D A+ + F + G FD V++ G + + D++ + Sbjct: 64 DFADPLAAKDSFTDAG-----FDILVNNAGIIRR-----ADSVEFSELDWDEVMDVNLKA 113 Query: 124 FVAMAKACRSML---NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 +A L ++ ++ L + + AK + + +AN + Sbjct: 114 LFFTTQAFAKELLAKGRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTKLLANEWAAK 173 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 G+ VNAI+ G I T ++ P R ED+ +A FL S + + Sbjct: 174 GINVNAIAPGYIETNNTEALRADAARNKAILERIPAGRWGHSEDIAGAAVFLSSAAADYV 233 Query: 241 SGEVVHVDGGF 251 G +++VDGG+ Sbjct: 234 HGAILNVDGGW 244 >1X1T-A nrPDB Length = 260 Score = 178 bits (453), Expect = 2e-45, Method: Composition-based stats. Identities = 58/266 (21%), Positives = 102/266 (38%), Gaps = 24/266 (9%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLK--GRVEEFAAQLGSDIV 60 L GK +VTG S I GIA A+ +GA++ D + AAQ G ++ Sbjct: 1 MLKGKVAVVTGSTS--GIGLGIATALAAQGADIVLNGFGDAAEIEKVRAGLAAQHGVKVL 58 Query: 61 LQ-CDVAEDASIDTMFAELGKVWPKFDGFVHSIGF---APGDQLDGDYVNAVTREGFKIA 116 D+++ ++ + + + D V++ G A + + +A+ Sbjct: 59 YDGADLSKGEAVRGLVDNAVRQMGRIDILVNNAGIQHTALIEDFPTEKWDAILALNLSAV 118 Query: 117 HDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANA 176 ++ + M K ++ ++ A N + AK + + A Sbjct: 119 FHGTAAALPHMKKQGF------GRIINIASAHGLVASANKSAYVAAKHGVVGFTKVTALE 172 Query: 177 MGPEGVRVNAISAGPIRTLAA----------SGIKDFRKMLAHCEAVTPIRRTVTIEDVG 226 +G+ NAI G +RT +G+ P + VT E +G Sbjct: 173 TAGQGITANAICPGWVRTPLVEKQISALAEKNGVDQETAARELLSEKQPSLQFVTPEQLG 232 Query: 227 NSAAFLCSDLSAGISGEVVHVDGGFS 252 +A FL SD +A I+G V VDGG++ Sbjct: 233 GTAVFLASDAAAQITGTTVSVDGGWT 258 >4CQL-A nrPDB Length = 261 Score = 178 bits (452), Expect = 2e-45, Method: Composition-based stats. Identities = 49/264 (18%), Positives = 93/264 (35%), Gaps = 21/264 (7%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSD--- 58 L LVTG S I ++ + EGA +A + GS Sbjct: 7 NRLRSALALVTGAGS--GIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGP 64 Query: 59 -----IVLQCDVAEDASIDTMFAELGKVWPKF-DGFVHSIGFAPGDQLDGDYVNAVTREG 112 Q DV+E + + ++ + + V G + L ++ + Sbjct: 65 PRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFL-----LHMSEDD 119 Query: 113 FKIAHDISSYSFVAMAKACRSMLNPGS---ALLTLSYLGAERAIPNYNVMGLAKASLEAN 169 + ++ + +A L +++ +S + + +KA + Sbjct: 120 WDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGL 179 Query: 170 VRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSA 229 + A +G G+R N++ G I T + +K++ + P+ EDV + Sbjct: 180 TQTAARELGRHGIRCNSVLPGFIATPMTQKV--PQKVVDKITEMIPMGHLGDPEDVADVV 237 Query: 230 AFLCSDLSAGISGEVVHVDGGFSI 253 AFL S+ S I+G V V GG + Sbjct: 238 AFLASEDSGYITGTSVEVTGGLFM 261 >4IS3-A nrPDB Length = 268 Score = 178 bits (452), Expect = 2e-45, Method: Composition-based stats. Identities = 49/257 (19%), Positives = 103/257 (40%), Gaps = 16/257 (6%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAEL-AFTYQNDKLKGRVEEFAAQLGSDI 59 M + K ++TG I + A+ GA++ F +++ + + + Sbjct: 20 MNLVQDKVTIITGGT--RGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYPEEE 77 Query: 60 VLQC--DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAH 117 VL D+ ++ ++ + + + D +++ G + + V+ E FK Sbjct: 78 VLGFAPDLTSRDAVMAAVGQVAQKYGRLDVMINNAGIT-----SNNVFSRVSEEEFKHIM 132 Query: 118 DISSYSFV---AMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMA 174 DI+ A C G + T S G ++ +KAS+ + Sbjct: 133 DINVTGVFNGAWCAYQCMKDAKKGVIINTASVTGIFGSLSGVG-YPASKASVIGLTHGLG 191 Query: 175 NAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCS 234 + + +RV ++ G + T +G + +++ P++R + E++ N FL S Sbjct: 192 REIIRKNIRVVGVAPGVVNTDMTNG--NPPEIMEGYLKALPMKRMLEPEEIANVYLFLAS 249 Query: 235 DLSAGISGEVVHVDGGF 251 DL++GI+ V VDG + Sbjct: 250 DLASGITATTVSVDGAY 266 >2AG5-A nrPDB Length = 246 Score = 178 bits (451), Expect = 3e-45, Method: Composition-based stats. Identities = 55/261 (21%), Positives = 103/261 (39%), Gaps = 22/261 (8%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 60 MG L GK I++T A + A +A REGA++ T N+ +E++ Sbjct: 1 MGRLDGKVIILTAAAQGIGQAAALA--FAREGAKVIATDINESKLQELEKY----PGIQT 54 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 DV + ID E+ + D + GF + V + + + +++ Sbjct: 55 RVLDVTKKKQIDQFANEVE----RLDVLFNVAGF-----VHHGTVLDCEEKDWDFSMNLN 105 Query: 121 SYSFVAMAKACRSML--NPGSALLTLSYLGAE-RAIPNYNVMGLAKASLEANVRYMANAM 177 S M KA + ++ +S + + + + N V KA++ + +A Sbjct: 106 VRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADF 165 Query: 178 GPEGVRVNAISAGPIRTLA----ASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLC 233 +G+R N + G + T + + + R T E++ +L Sbjct: 166 IQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLA 225 Query: 234 SDLSAGISGEVVHVDGGFSIA 254 SD SA ++G V +DGG+S+ Sbjct: 226 SDESAYVTGNPVIIDGGWSLG 246 >4FC7-A nrPDB Length = 277 Score = 177 bits (450), Expect = 4e-45, Method: Composition-based stats. Identities = 51/254 (20%), Positives = 102/254 (40%), Gaps = 14/254 (5%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN-DKLKGRVEEFAAQLGSDIV- 60 L K +TG S I + IA+ R G ++ ++ + A G + Sbjct: 24 LLRDKVAFITGGGS--GIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLP 81 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIG---FAPGDQLDGDYVNAVTREGFKIAH 117 L DV ++ + K + + D ++ P L + V Sbjct: 82 LSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTF 141 Query: 118 DISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAM 177 ++S + + + G ++ ++ R G AKA+++A R++A Sbjct: 142 NVSRVLYEKFFR------DHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEW 195 Query: 178 GPEGVRVNAISAGPIR-TLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDL 236 GP+ +RVN+++ GPI T + + L+ +P++R ++ +S +L S L Sbjct: 196 GPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPL 255 Query: 237 SAGISGEVVHVDGG 250 ++ ++G V+ DGG Sbjct: 256 ASYVTGAVLVADGG 269 >5JS6-A nrPDB Length = 274 Score = 177 bits (449), Expect = 5e-45, Method: Composition-based stats. Identities = 50/235 (21%), Positives = 95/235 (40%), Gaps = 13/235 (5%) Query: 25 AQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPK 84 +A GA + +++ +E+ +L + + CDV ++ + T+ +E + + + Sbjct: 28 VRAFVNSGARVVICDKDESGGRALEQ---ELPGAVFILCDVTQEDDVKTLVSETIRRFGR 84 Query: 85 FDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPG-SALLT 143 D V++ G P Q + + +GF+ +++ + K L ++ Sbjct: 85 LDCVVNNAGHHPPPQRPEE----TSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNVIN 140 Query: 144 LSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRT----LAASG 199 +S L K ++ A + +A P GVRVN IS G I T A+ Sbjct: 141 ISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAAL 200 Query: 200 IKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIA 254 + D R + P+ R +VG +A FL S + +G + V GG + Sbjct: 201 MPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGIELLVTGGAELG 254 >4RZI-B nrPDB Length = 240 Score = 177 bits (449), Expect = 5e-45, Method: Composition-based stats. Identities = 51/252 (20%), Positives = 91/252 (36%), Gaps = 21/252 (8%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 L K I+VTG I I + + GA++AFT + + Sbjct: 6 LEDKVIVVTGG--NRGIGAAIVKLLQEMGAKVAFTDLATDGGNT---------EALGVVA 54 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 +V + S+ AE+ G V + G + +T + +++ Sbjct: 55 NVTDLESMTAAAAEITDKLGPVYGVVANAGITKDNFFPK-----LTPADWDAVLNVNLKG 109 Query: 124 FVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 K + +++ +S + ER KA + ++ +A G Sbjct: 110 VAYSIKPFIEGMYERKAGSIVAISSISGERGNVGQTNYSATKAGVIGMMKSLAREGARYG 169 Query: 182 VRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSD-LSAGI 240 VR NA++ G I T I+ + P RR E++ + AFL S S+ + Sbjct: 170 VRANAVAPGFIDTEMTLAIR--EDIREKITKEIPFRRFGKPEEIAWAVAFLLSPVASSYV 227 Query: 241 SGEVVHVDGGFS 252 +GEV+ V+G Sbjct: 228 TGEVLRVNGAHH 239 >4GKB-A nrPDB Length = 258 Score = 176 bits (448), Expect = 6e-45, Method: Composition-based stats. Identities = 62/255 (24%), Positives = 107/255 (41%), Gaps = 14/255 (5%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 L K ++VTG AS + A + + E A ++ ++ A + L Sbjct: 5 LQDKVVIVTGGASGIGGAISM--RLAEERAIPVVFARHAPDGAFLDALAQRQPRATYLPV 62 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 ++ +DA A+ + + DG V++ G G LD R+ F + + + Sbjct: 63 ELQDDAQCRDAVAQTIATFGRLDGLVNNAGVNDGIGLDAG------RDAFVASLERNLIH 116 Query: 124 FVAMAKACRSMLNP-GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGV 182 + AMA C L A++ +S A N + +K + A R A A+ GV Sbjct: 117 YYAMAHYCVPHLKATRGAIVNISSKTAVTGQGNTSGYCASKGAQLALTREWAVALREHGV 176 Query: 183 RVNAISAGPIRTLAASG----IKDFRKMLAHCEAVTPIR-RTVTIEDVGNSAAFLCSDLS 237 RVNA+ + T +D LA A P+ R T +++ ++A FL S + Sbjct: 177 RVNAVIPAEVMTPLYRNWIATFEDPEAKLAEIAAKVPLGRRFTTPDEIADTAVFLLSPRA 236 Query: 238 AGISGEVVHVDGGFS 252 + +GE + VDGG++ Sbjct: 237 SHTTGEWLFVDGGYT 251 >2CFC-A nrPDB Length = 250 Score = 176 bits (448), Expect = 6e-45, Method: Composition-based stats. Identities = 43/253 (16%), Positives = 94/253 (37%), Gaps = 14/253 (5%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQL-----GSDIVL 61 + +VTG +S + IA G +A D +EE A + + Sbjct: 3 RVAIVTGASSGNGL--AIATRFLARGDRVA---ALDLSAETLEETARTHWHAYADKVLRV 57 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 + DVA++ ++ A + + D V++ G + ++ E F ++ Sbjct: 58 RADVADEGDVNAAIAATMEQFGAIDVLVNNAGITGNSE--AGVLHTTPVEQFDKVMAVNV 115 Query: 122 YSFVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 +A + ++ ++ + + A P + +K ++ + +A Sbjct: 116 RGIFLGCRAVLPHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDYAG 175 Query: 180 EGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAG 239 G+R NA+ G I T D ++ A P + T V ++ FL + + Sbjct: 176 SGIRCNAVCPGMIETPMTQWRLDQPELRDQVLARIPQKEIGTAAQVADAVMFLAGEDATY 235 Query: 240 ISGEVVHVDGGFS 252 ++G + +DG ++ Sbjct: 236 VNGAALVMDGAYT 248 >5B1Y-A nrPDB Length = 270 Score = 176 bits (448), Expect = 7e-45, Method: Composition-based stats. Identities = 51/247 (20%), Positives = 102/247 (41%), Gaps = 10/247 (4%) Query: 9 ILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDK-LKGRVEEFAAQLGS--DIVLQCDV 65 LVTG + I REG + Y++ L + E A +LGS ++ DV Sbjct: 26 ALVTGGS--RGIGRATVLRFAREGWSVVIAYKSRADLAEKTAEEARRLGSPEAYTVRVDV 83 Query: 66 AEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFV 125 + S+ M + +G++ P + V++ G QL G +++ + +++ V Sbjct: 84 GDPDSVTEMSSRVGELIPHLNVLVNAAGVL---QLGGIEETSISEWEETLRVNLTGVYLV 140 Query: 126 AMAKACRSMLNPGSALLTLSYLGAERAIPNYNV-MGLAKASLEANVRYMANAMGPEGVRV 184 ++++ ++ + E V +KA + + +A + G+RV Sbjct: 141 TKLLLPLLRKAKWASIVNVASIAGETGNVVAGVAYSASKAGVIGLTKRLAVQLAGYGIRV 200 Query: 185 NAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSD-LSAGISGE 243 NA++ + T D + ++ P++ + EDV + FL S GI+G Sbjct: 201 NAVAPSFVETDMTRSFLDTPEKRERIASLHPLKIILKPEDVAEAILFLADPRRSRGITGH 260 Query: 244 VVHVDGG 250 V+ ++ G Sbjct: 261 VLSINAG 267 >2X9N-A nrPDB Length = 288 Score = 176 bits (448), Expect = 7e-45, Method: Composition-based stats. Identities = 57/267 (21%), Positives = 106/267 (39%), Gaps = 27/267 (10%) Query: 9 ILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGR--VEEF-AAQLGSDIVLQCDV 65 +VTG A + I IA +H+ G + Y N +E + + +V Q D+ Sbjct: 26 AVVTGAAKR--IGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADL 83 Query: 66 AE----DASIDTMFAELGKVWPKFDGFVHSI-GFAPGDQLDGDYVNAV------TREGFK 114 AS + + + + + D V++ F P + GD+ + T+ Sbjct: 84 TNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDNSNGKTVETQVAEL 143 Query: 115 IAHDISSYSFVAMAKACRSML-NPGSALLTLSYLGAERAIPN-----YNVMGLAKASLEA 168 I + + + M+ A R NP LS + A+ + +++ + K +L Sbjct: 144 IGTNAIAPFLLTMSFAQRQKGTNPNCTSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVG 203 Query: 169 NVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIR-RTVTIEDVGN 227 + A + P G+RVN ++ G A G + P+ R + E + + Sbjct: 204 LTQSAALELAPYGIRVNGVAPGVSLLPVAMG----EEEKDKWRRKVPLGRREASAEQIAD 259 Query: 228 SAAFLCSDLSAGISGEVVHVDGGFSIA 254 + FL S + I+G ++ VDGG S+ Sbjct: 260 AVIFLVSGSAQYITGSIIKVDGGLSLV 286 >1NFF-A nrPDB Length = 260 Score = 174 bits (441), Expect = 4e-44, Method: Composition-based stats. Identities = 52/261 (19%), Positives = 99/261 (37%), Gaps = 19/261 (7%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVL 61 G L+GK LV+G A + +AM EGA++ F D+ + A + Sbjct: 3 GRLTGKVALVSGGA--RGMGASHVRAMVAEGAKVVFGDILDEEGKAMAAELADAAR--YV 58 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS- 120 DV + A + V++ G L+ + ++ D++ Sbjct: 59 HLDVTQPAQWKAAVDTAVTAFGGLHVLVNNAGI-----LNIGTIEDYALTEWQRILDVNL 113 Query: 121 SYSFVAMAKACRSMLNPG-SALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 + F+ + + M G +++ +S + + K ++ + A +GP Sbjct: 114 TGVFLGIRAVVKPMKEAGRGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTALELGP 173 Query: 180 EGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAG 239 G+RVN+I G ++T + T + R +V N +L SD S+ Sbjct: 174 SGIRVNSIHPGLVKTPMT-------DWVPEDIFQTALGRAAEPVEVSNLVVYLASDESSY 226 Query: 240 ISGEVVHVDGGFSIAAMNELE 260 +G VDGG ++A + + Sbjct: 227 STGAEFVVDGG-TVAGLAHND 246 >3UVE-A nrPDB Length = 286 Score = 174 bits (441), Expect = 4e-44, Method: Composition-based stats. Identities = 51/282 (18%), Positives = 93/282 (32%), Gaps = 39/282 (13%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAF-----------------TYQNDKL 44 G + GK VTG A A + +EGA++ + L Sbjct: 7 GRVEGKVAFVTGAA--RGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDL 64 Query: 45 KGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDY 104 + + + DV + ++ + + D V + G G GD Sbjct: 65 AETADLVKGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNG----GDT 120 Query: 105 VNAVTREGFKIAHDISSYSFVAMAKACRSML---NPGSALLTLSYLGAERAIPNYNVMGL 161 ++ + E + DI+ KA + G +++ S +G +A P+ Sbjct: 121 LDKTSEEDWTEMIDINLAGVWKTVKAGVPHMIAGGRGGSIILTSSVGGLKAYPHTGHYVA 180 Query: 162 AKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIR---- 217 AK + +R +G +RVN++ ++T F+ E P Sbjct: 181 AKHGVVGLMRAFGVELGQHMIRVNSVHPTHVKTPMLHNEGTFKMFRPDLENPGPDDMAPI 240 Query: 218 ---------RTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGG 250 V D+ N+ F SD + I+G + +D G Sbjct: 241 CQMFHTLPIPWVEPIDISNAVLFFASDEARYITGVTLPIDAG 282 >4DBZ-A nrPDB Length = 281 Score = 173 bits (440), Expect = 5e-44, Method: Composition-based stats. Identities = 45/257 (17%), Positives = 97/257 (37%), Gaps = 19/257 (7%) Query: 8 RILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDK-LKGRVEEFAAQLGSDIVLQCDVA 66 LVTG S I IA+ + +EG + + ++ L+ ++E CDV Sbjct: 28 VALVTGATS--GIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGVEADGRTCDVR 85 Query: 67 EDASIDTMFAELGKVWPKFDGFVHSIG---FAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 I+ + A + + + D V++ G +L + V ++ Sbjct: 86 SVPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELADELWLDVVETNLTGVFRVTK-- 143 Query: 124 FVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVR 183 + KA + ++ ++ G ++ + + +K + + + + G+ Sbjct: 144 --QVLKAGGMLERGTGRIVNIASTGGKQGLVHAAPYSASKHGVVGFTKALGLELARTGIT 201 Query: 184 VNAISAGPIRTLAASGIKDF---------RKMLAHCEAVTPIRRTVTIEDVGNSAAFLCS 234 VNA+ G + T A+ +++ + A PI R V +V A+L Sbjct: 202 VNAVCPGFVETPMAASVREHYSDIWEVSTEEAFDRITARVPIGRYVQPSEVAEMVAYLIG 261 Query: 235 DLSAGISGEVVHVDGGF 251 +A ++ + ++V GG Sbjct: 262 PGAAAVTAQALNVCGGL 278 >1CYD-A nrPDB Length = 244 Score = 173 bits (439), Expect = 6e-44, Method: Composition-based stats. Identities = 59/252 (23%), Positives = 100/252 (39%), Gaps = 19/252 (7%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELA-FTYQNDKLKGRVEEFAAQLGSDIVLQ 62 SG R LVTG I +A+H GA++ T N L A + + Sbjct: 5 FSGLRALVTGAGK--GIGRDTVKALHASGAKVVAVTRTNSDLVS----LAKECPGIEPVC 58 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSY 122 D+ + + D V++ VT+E F + ++ Sbjct: 59 VDLGD----WDATEKALGGIGPVDLLVNNAALVIMQPF-----LEVTKEAFDRSFSVNLR 109 Query: 123 SFVAMAK-ACRSMLNPG--SALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 S +++ R M+N G +++ +S + A PN K ++ + MA +GP Sbjct: 110 SVFQVSQMVARDMINRGVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMELGP 169 Query: 180 EGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAG 239 +RVN+++ + T + + + P+R+ +EDV NS FL SD SA Sbjct: 170 HKIRVNSVNPTVVLTDMGKKVSADPEFARKLKERHPLRKFAEVEDVVNSILFLLSDRSAS 229 Query: 240 ISGEVVHVDGGF 251 SG + VD G+ Sbjct: 230 TSGGGILVDAGY 241 >1P33-A nrPDB Length = 289 Score = 173 bits (439), Expect = 6e-44, Method: Composition-based stats. Identities = 63/285 (22%), Positives = 107/285 (37%), Gaps = 44/285 (15%) Query: 8 RILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEF---AAQLGSDIVLQCD 64 LVTG A +L IA+A+H EG + Y A + S I +Q D Sbjct: 9 VALVTGAAKRLG--SSIAEALHAEGYTVCLHYHRSAADASTLAATLNARRPNSAITVQAD 66 Query: 65 VAEDAS-----------------IDTMFAELGKVWPKFDGFVHSIG-FAPGDQLDGDYVN 106 ++ A+ + W + D V++ F P L D Sbjct: 67 LSNVATASFSETDGSVPVTLFSRCSALVDACYMHWGRCDVLVNNASSFYPTPLLRKDAGE 126 Query: 107 AVTREGFKIAHDISSY----------SFVAMAKACR----SMLNPGSALLTLSYLGAERA 152 + G K + ++++ F+ A A R G++ ++ + A + Sbjct: 127 GGSSVGDKESLEVAAADLFGSNAIAPYFLIKAFAQRVADTRAEQRGTSYSIVNMVDAMTS 186 Query: 153 IP--NYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHC 210 P Y + +AK +LE R A + +RVN +S G L+ + Sbjct: 187 QPLLGYTMYTMAKEALEGLTRSAALELASLQIRVNGVSPG----LSVLPDDMPFSVQEDY 242 Query: 211 EAVTPI-RRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIA 254 P+ +R + E+V + FLCS + I+G + VDGG+S+ Sbjct: 243 RRKVPLYQRNSSAEEVSDVVIFLCSPKAKYITGTCIKVDGGYSLT 287 >2FWM-X nrPDB Length = 250 Score = 173 bits (439), Expect = 7e-44, Method: Composition-based stats. Identities = 53/262 (20%), Positives = 105/262 (40%), Gaps = 26/262 (9%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 SGK + VTG I Y A A GA++ G + F + Sbjct: 5 FSGKNVWVTGAGK--GIGYATALAFVEAGAKVT---------GFDQAFTQEQYPFATEVM 53 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 DVA+ A + + L + D V++ G L + +++E ++ ++ Sbjct: 54 DVADAAQVAQVCQRLLAETERLDALVNAAGI-----LRMGATDQLSKEDWQQTFAVNVGG 108 Query: 124 FVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 + + + G A++T++ A + G +KA+L++ + + G Sbjct: 109 AFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSG 168 Query: 182 VRVNAISAGPIRTLAASGIK-----DFRKMLAHCEAV---TPIRRTVTIEDVGNSAAFLC 233 VR N +S G T + + +++ E P+ + +++ N+ FL Sbjct: 169 VRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLA 228 Query: 234 SDLSAGISGEVVHVDGGFSIAA 255 SDL++ I+ + + VDGG ++ A Sbjct: 229 SDLASHITLQDIVVDGGSTLGA 250 >2B4Q-A nrPDB Length = 276 Score = 172 bits (437), Expect = 1e-43, Method: Composition-based stats. Identities = 53/257 (20%), Positives = 106/257 (41%), Gaps = 14/257 (5%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 L+G+ LVTG + I IAQ + GA + ++ + + G + Sbjct: 27 LAGRIALVTGGS--RGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYGDCQAIPA 84 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 D++ +A + LG++ + D V++ G + G L+ V+ G++ ++ S Sbjct: 85 DLSSEAGARRLAQALGELSARLDILVNNAGTSWGAALESYPVS-----GWEKVMQLNVTS 139 Query: 124 FVAMAKACRSMLNPGSA------LLTLSYLGAERAIPNYN-VMGLAKASLEANVRYMANA 176 + + +L ++ ++ + + A+ G +KA+L R +A Sbjct: 140 VFSCIQQLLPLLRRSASAENPARVINIGSVAGISAMGEQAYAYGPSKAALHQLSRMLAKE 199 Query: 177 MGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDL 236 + E + VN I+ G + I + + L A P+ R E++ A L Sbjct: 200 LVGEHINVNVIAPGRFPSRMTRHIANDPQALEADSASIPMGRWGRPEEMAALAISLAGTA 259 Query: 237 SAGISGEVVHVDGGFSI 253 A ++G V+ +DGGF + Sbjct: 260 GAYMTGNVIPIDGGFHL 276 >4EGF-A nrPDB Length = 266 Score = 171 bits (434), Expect = 3e-43, Method: Composition-based stats. Identities = 59/258 (22%), Positives = 110/258 (42%), Gaps = 14/258 (5%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN-DKLKGRVEEFAAQLGSDI-V 60 L GKR L+TG I IA+A GA L + ++ +L Q G+D+ Sbjct: 17 RLDGKRALITGATK--GIGADIARAFAAAGARLVLSGRDVSELDAARRALGEQFGTDVHT 74 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFA-PGDQLDGDYVNAVTREGFKIAHDI 119 + D+AE + + + + D V++ G + P +D D F + Sbjct: 75 VAIDLAEPDAPAELARRAAEAFGGLDVLVNNAGISHPQPVVDTDPQL------FDATIAV 128 Query: 120 SSYSFVAMAKACRSML---NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANA 176 + + +A A + G A++T++ A +P++ +KA L + +A Sbjct: 129 NLRAPALLASAVGKAMVAAGEGGAIITVASAAALAPLPDHYAYCTSKAGLVMATKVLARE 188 Query: 177 MGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDL 236 +GP G+R N++ + T + A A P+ R +V ++ +L SD Sbjct: 189 LGPHGIRANSVCPTVVLTEMGQRVWGDEAKSAPMIARIPLGRFAVPHEVSDAVVWLASDA 248 Query: 237 SAGISGEVVHVDGGFSIA 254 ++ I+G + VDGG+++ Sbjct: 249 ASMINGVDIPVDGGYTMG 266 >5EJ2-A nrPDB Length = 308 Score = 170 bits (431), Expect = 6e-43, Method: Composition-based stats. Identities = 55/278 (19%), Positives = 98/278 (35%), Gaps = 35/278 (12%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAF-------------TYQNDKLKGRV 48 G ++GK ++G A A + +EGA++ + L Sbjct: 33 GRVAGKVAFISGAA--RGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETA 90 Query: 49 EEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAV 108 + + Q DV + ++ + + + D V + G DG ++ + Sbjct: 91 DLVKDLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGV----GTDGRKLHKI 146 Query: 109 TREGFKIAHDISSYSFVAMAKACRSML---NPGSALLTLSYLGAERAIPNYNVMGLAKAS 165 ++ DI+ KA + G +++ S +G +A PN AK Sbjct: 147 RDNVWQDMIDINLTGVWHTVKAGVPHVLSGGRGGSIVLTSSVGGRKAYPNTGHYIAAKHG 206 Query: 166 LEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTP--------IR 217 + +R A +GP +RVNA+ + T + FR E P + Sbjct: 207 VIGLMRAFAVELGPHMIRVNAVLPTQVSTTMVMNDQTFRLFRPDLENPGPDDFAPISQMM 266 Query: 218 R-----TVTIEDVGNSAAFLCSDLSAGISGEVVHVDGG 250 V D+ N+ FL SD S ++G + VD G Sbjct: 267 HTLPVPWVDASDISNAVLFLASDESRYVTGVSLPVDAG 304 >2QHX-A nrPDB Length = 328 Score = 170 bits (430), Expect = 7e-43, Method: Composition-based stats. Identities = 66/286 (23%), Positives = 104/286 (36%), Gaps = 46/286 (16%) Query: 8 RILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEF---AAQLGSDIVLQCD 64 LVTG A +L IA+ +H EG + Y + A + S I +Q D Sbjct: 48 VALVTGAAKRLG--RSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQAD 105 Query: 65 VAEDAS-----------------IDTMFAELGKVWPKFDGFVHSIG-FAPGDQL----DG 102 ++ A+ + A W + D V++ F P L DG Sbjct: 106 LSNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDG 165 Query: 103 DYVNAVTREGFKIAHDISSYS------FVAMAKACR----SMLNPGSALLTLSYLGAERA 152 RE + A S F+ A A R + G+ ++ + A Sbjct: 166 HEPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTN 225 Query: 153 IP--NYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAG--PIRTLAASGIKDFRKMLA 208 P Y + +AK +LE R A + P +RVN + G + + + Sbjct: 226 QPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLSVLVDDMPPAVWE-----G 280 Query: 209 HCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIA 254 H V +R + +V + FLCS + I+G V VDGG+S+ Sbjct: 281 HRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLT 326 >2BFA-A nrPDB Length = 288 Score = 169 bits (429), Expect = 1e-42, Method: Composition-based stats. Identities = 66/286 (23%), Positives = 104/286 (36%), Gaps = 46/286 (16%) Query: 8 RILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEF---AAQLGSDIVLQCD 64 LVTG A +L IA+ +H EG + Y + A + S I +Q D Sbjct: 8 VALVTGAAKRLG--RSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQAD 65 Query: 65 VAEDAS-----------------IDTMFAELGKVWPKFDGFVHSIG-FAPGDQL----DG 102 ++ A+ + A W + D V++ F P L DG Sbjct: 66 LSNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDG 125 Query: 103 DYVNAVTREGFKIAHDISSYS------FVAMAKACR----SMLNPGSALLTLSYLGAERA 152 RE + A S F+ A A R + G+ ++ + A Sbjct: 126 HEPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTN 185 Query: 153 IP--NYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAG--PIRTLAASGIKDFRKMLA 208 P Y + +AK +LE R A + P +RVN + G + + + Sbjct: 186 QPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLSVLVDDMPPAVWE-----G 240 Query: 209 HCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIA 254 H V +R + +V + FLCS + I+G V VDGG+S+ Sbjct: 241 HRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLT 286 >3WTC-A nrPDB Length = 262 Score = 169 bits (429), Expect = 1e-42, Method: Composition-based stats. Identities = 49/261 (18%), Positives = 90/261 (34%), Gaps = 20/261 (7%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTY-QNDKLKGRVEEFAAQLGSDIVLQ 62 LSGK VTG A I IA + ++GA++ + D L +E A + L Sbjct: 6 LSGKIAAVTGAAQ--GIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEALGRRAVALT 63 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSY 122 D++ + A+ K D V++ G + + + I+ Sbjct: 64 ADISNRDQFRSTLADAAKTLGGLDIMVNNAGICQVKP-----ILDIEPAEIEKIFSINVQ 118 Query: 123 SFVAMAKACRSMLNPGSA---LLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 + +A ++ ++ + P K ++ A + A + Sbjct: 119 GVLWGMQAAATLFKEKGTKGKIINACSIAGHEGYPLLGAYSATKFAVRALTQSAAKELAS 178 Query: 180 EGVRVNAISAGPIRTLAASGIKDFRKMLAHCE---------AVTPIRRTVTIEDVGNSAA 230 G+ VN+ G + T I + E + R T +DV A Sbjct: 179 SGITVNSYCPGIVGTDMWVTIDKRMAEITGTEIGATYKKYVEGIALGRVETADDVAGFVA 238 Query: 231 FLCSDLSAGISGEVVHVDGGF 251 +L S + ++G+ V +DGG Sbjct: 239 YLSSSDADYMTGQSVLIDGGL 259 >1W73-A nrPDB Length = 302 Score = 168 bits (427), Expect = 2e-42, Method: Composition-based stats. Identities = 64/256 (25%), Positives = 112/256 (43%), Gaps = 15/256 (5%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN-DKLKGRVEEFAAQLGSDI- 59 GK + + G+ + GA+ + D LK E+ ++Q G+ + Sbjct: 22 NSFQGKVAFI--TGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVH 79 Query: 60 VLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIG---FAPGDQLDGDYVNAVTREGFKIA 116 +QCDV + + +EL KV + +++ +P ++L + +T Sbjct: 80 AIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITD------ 133 Query: 117 HDISSYSFVAMAKACRSML-NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMAN 175 ++ +FV + + + G+A L+++ + AE AKA +EA + +A Sbjct: 134 IVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAA 193 Query: 176 AMGPEGVRVNAISAGPIRTLAA-SGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCS 234 G G+R N I GPI+T A S + P R T+E++ N AAFLCS Sbjct: 194 EWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCS 253 Query: 235 DLSAGISGEVVHVDGG 250 D ++ I+G V+ DGG Sbjct: 254 DYASWINGAVIKFDGG 269 >3T7C-A nrPDB Length = 299 Score = 167 bits (424), Expect = 3e-42, Method: Composition-based stats. Identities = 59/279 (21%), Positives = 100/279 (35%), Gaps = 37/279 (13%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTY-------------QNDKLKGRV 48 G + GK +TG A ++ I + REGA++ D L V Sbjct: 24 GKVEGKVAFITGAARGQGRSHAI--TLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETV 81 Query: 49 EEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAV 108 + A I Q DV + ++ + + D + + A +G +N + Sbjct: 82 RQVEALGRRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALAS----EGTRLNRM 137 Query: 109 TREGFKIAHDISSYSFVAMAKACRSML---NPGSALLTLSYLGAERAIPNYNVMGLAKAS 165 + ++ D++ A+ + G +++ S +G R N +K Sbjct: 138 DPKTWRDMIDVNLNGAWITARVAIPHIMAGKRGGSIVFTSSIGGLRGAENIGNYIASKHG 197 Query: 166 LEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVT----------- 214 L +R MA +GP +RVN + + T +R E T Sbjct: 198 LHGLMRTMALELGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFQVASRQM 257 Query: 215 ---PIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGG 250 PI V D+ N+ FL SD + I+G + VDGG Sbjct: 258 HVLPIP-YVEPADISNAILFLVSDDARYITGVSLPVDGG 295 >2HSD-A nrPDB Length = 253 Score = 164 bits (415), Expect = 4e-41, Method: Composition-based stats. Identities = 52/254 (20%), Positives = 100/254 (39%), Gaps = 15/254 (5%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQ- 62 LSGK +++TG A + A+ GA + D L A +LG Q Sbjct: 3 LSGKTVIITGGA--RGLGAEAARQAVAAGARVVLA---DVLDEEGAATARELGDAARYQH 57 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSY 122 DV + + A + + DG V++ G + G L+ + + E F+ +I+ Sbjct: 58 LDVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETE-----SVERFRKVVEINLT 112 Query: 123 SFVAMAKACRSMLN--PGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 K + G +++ +S + + G +K + + A +G + Sbjct: 113 GVFIGMKTVIPAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTD 172 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI 240 +RVN++ G T + + + TP+ R ++ + L SD S+ + Sbjct: 173 RIRVNSVHPGMTYTPMTA--ETGIRQGEGNYPNTPMGRVGEPGEIAGAVVKLLSDTSSYV 230 Query: 241 SGEVVHVDGGFSIA 254 +G + VDGG++ Sbjct: 231 TGAELAVDGGWTTG 244 >3UN1-A nrPDB Length = 260 Score = 160 bits (406), Expect = 4e-40, Method: Composition-based stats. Identities = 55/254 (21%), Positives = 100/254 (39%), Gaps = 26/254 (10%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 60 M K +++TG + I G+ +A + T ++ K Sbjct: 23 MMRNQQKVVVITGASQ--GIGAGLVRAYRDRNYRVVATSRSIKPSAD--------PDIHT 72 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 + D+++ + D + E + + + D V++ G +T+E + ++ Sbjct: 73 VAGDISKPETADRIVREGIERFGRIDSLVNNAGV-----FLAKPFVEMTQEDYDHNLGVN 127 Query: 121 SYSFVAM-AKACRSMLNPGSALL---TLSYLGAERAIPNYNVMGLAKASLEANVRYMANA 176 F + +A ML GS + T S + + L K L A R +A Sbjct: 128 VAGFFHITQRAAAEMLKQGSGHIVSITTSLVDQPMVGMPSALASLTKGGLNAVTRSLAME 187 Query: 177 MGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDL 236 GVRVNA+S G I+T + + + P+ R I DV ++ +L + Sbjct: 188 FSRSGVRVNAVSPGVIKTPMHPA-----ETHSTLAGLHPVGRMGEIRDVVDAVLYL--EH 240 Query: 237 SAGISGEVVHVDGG 250 + I+GE++HVDGG Sbjct: 241 AGFITGEILHVDGG 254 >2PTG-A nrPDB Length = 319 Score = 160 bits (406), Expect = 5e-40, Method: Composition-based stats. Identities = 80/306 (26%), Positives = 129/306 (42%), Gaps = 57/306 (18%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAF----------------------TYQN 41 L GK V GVA + I + + GA + ++ Sbjct: 7 LRGKTAFVAGVADSNGYGWAICKLLRAAGARVLVGTWPPVYSIFKKGLESSRFEQDSFYA 66 Query: 42 DKLKGRVEEFAAQLGSDIVL------------QCDVAEDAS------------IDTMFAE 77 + +V AA+ D+V DV + S I + Sbjct: 67 QEPSSKVAAEAAEKPVDLVFDKIYPLDAVFDTPQDVPPEVSSNKRYAGVGGFTISEVAEA 126 Query: 78 LGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNP 137 + + D VHS A G ++ + +R+G+ A SSYSFV++ + ++ Sbjct: 127 VRADVGQIDILVHS--LANGPEVTKPLL-QTSRKGYLAAVSSSSYSFVSLLQHFLPLMKE 183 Query: 138 GSALLTLSYLGAERAIPNYNV-MGLAKASLEANVRYMANAMGP-EGVRVNAISAGPIRTL 195 G + L LSY+ +E+ IP Y M AKA+LE++ R +A G VRVN ISAGP+++ Sbjct: 184 GGSALALSYIASEKVIPGYGGGMSSAKAALESDCRTLAFEAGRARAVRVNCISAGPLKSR 243 Query: 196 AASGIK------DFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDG 249 AAS I + + EA P+++ + +DVG +A FL S L+ ++G ++VD Sbjct: 244 AASAIGKAGDKTFIDLAIDYSEANAPLQKELESDDVGRAALFLLSPLARAVTGATLYVDN 303 Query: 250 GFSIAA 255 G Sbjct: 304 GLHAMG 309 >3GDF-A nrPDB Length = 267 Score = 160 bits (406), Expect = 5e-40, Method: Composition-based stats. Identities = 57/258 (22%), Positives = 100/258 (38%), Gaps = 19/258 (7%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDK--LKGRVEEFAAQLG-SDIV 60 L GK ++VTG + + A+ GA +A TY + + V+E G Sbjct: 18 LKGKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKTYGIKAKA 77 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 +C V S + + ++ + + D F+ + G + + E + + Sbjct: 78 YKCQVDSYESCEKLVKDVVADFGQIDAFIANAGATADSG-----ILDGSVEAWNHVVQVD 132 Query: 121 SYSFVAMAKACRSMLNP---GSALLTLSYLGAERAIPN-YNVMGLAKASLEANVRYMANA 176 AKA GS ++T S G P +AKA R +AN Sbjct: 133 LNGTFHCAKAVGHHFKERGTGSLVITASMSGHIANFPQEQTSYNVAKAGCIHMARSLANE 192 Query: 177 MGPEGVRVNAISAGPIRTLAASGIKDF--RKMLAHCEAVTPIRRTVTIEDVGNSAAFLCS 234 RVN+IS G I T G+ DF ++ ++ P+ R +++ + + S Sbjct: 193 WRDFA-RVNSISPGYIDT----GLSDFVPKETQQLWHSMIPMGRDGLAKELKGAYVYFAS 247 Query: 235 DLSAGISGEVVHVDGGFS 252 D S +G + +DGG++ Sbjct: 248 DASTYTTGADLLIDGGYT 265 >2BGM-A nrPDB Length = 278 Score = 160 bits (405), Expect = 7e-40, Method: Composition-based stats. Identities = 51/235 (21%), Positives = 85/235 (36%), Gaps = 11/235 (4%) Query: 25 AQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPK 84 A+ R GA++ D +V + CDV +D + + K Sbjct: 33 AKLFVRYGAKVVIADIADDHGQKVCNNIGSPDVISFVHCDVTKDEDVRNLVDTTIAKHGK 92 Query: 85 FDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSML---NPGSAL 141 D ++G + E FK DI+ Y +AK ++ GS + Sbjct: 93 LDIMFGNVGVLSTTPYS---ILEAGNEDFKRVMDINVYGAFLVAKHAARVMIPAKKGSIV 149 Query: 142 LTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISA----GPIRTLAA 197 T S +V K ++ + +G G+RVN +S P+ T Sbjct: 150 FTASISSFTAGEGVSHVYTATKHAVLGLTTSLCTELGEYGIRVNCVSPYIVASPLLTDVF 209 Query: 198 SGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFS 252 + LAH A + EDV ++ A+L D S +SG + +DGG++ Sbjct: 210 GVDSSRVEELAHQAANL-KGTLLRAEDVADAVAYLAGDESKYVSGLNLVIDGGYT 263 >1H5Q-A nrPDB Length = 265 Score = 158 bits (401), Expect = 2e-39, Method: Composition-based stats. Identities = 56/257 (21%), Positives = 98/257 (38%), Gaps = 21/257 (8%) Query: 6 GKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQ--LGSDIVLQC 63 K I+VTG I +A+ GA +A Y++ V E + QC Sbjct: 14 NKTIIVTGG--NRGIGLAFTRAVAAAGANVAVIYRSAADAVEVTEKVGKEFGVKTKAYQC 71 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 DV+ + ++ G + + G + +T E F +D++ + Sbjct: 72 DVSNTDIVTKTIQQIDADLGPISGLIANAGVSVVKP-----ATELTHEDFAFVYDVNVFG 126 Query: 124 FV----AMAKACRSMLNPGSALLTLSYLGAERAIPNYNV------MGLAKASLEANVRYM 173 A+AK GS ++T S + N +KA+ V+ + Sbjct: 127 VFNTCRAVAKLWLQKQQKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSSKAACSNLVKGL 186 Query: 174 ANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLC 233 A G+RVNA+S G + T + + +K+ H + P+ R E++ A L Sbjct: 187 AAEWASAGIRVNALSPGYVNTDQTAHMD--KKIRDHQASNIPLNRFAQPEEMTGQAILLL 244 Query: 234 SDLSAGISGEVVHVDGG 250 SD + ++G +DGG Sbjct: 245 SDHATYMTGGEYFIDGG 261 >3V8B-A nrPDB Length = 283 Score = 157 bits (397), Expect = 5e-39, Method: Composition-based stats. Identities = 55/257 (21%), Positives = 96/257 (37%), Gaps = 22/257 (8%) Query: 8 RILVTGVASKLSIAYGIAQAMHREGAEL-AFTYQNDKLKGRVEEFAAQLGSDIVLQCDVA 66 L+TG S I A A+ +G + A +++ +E G I L+ DV+ Sbjct: 30 VALITGAGS--GIGRATALALAADGVTVGALGRTRTEVEEVADEIVGAGGQAIALEADVS 87 Query: 67 EDASIDTMFAELGKVWPKFDGFVHSIGF----APGDQLDGDYVNAVTREGFKIAHDISSY 122 ++ + +L + D V + G AP D L + + Sbjct: 88 DELQMRNAVRDLVLKFGHLDIVVANAGINGVWAPIDDLKPFEWDETIAVNLRGTFLTLHL 147 Query: 123 SFVAMAKACRSMLNPGSALLTLSYLGAERAI--PNYNVMGLAKASLEANVRYMANAMGPE 180 + + + G A++ +S + R P KA+ A V+ +A +G Sbjct: 148 TVPYLKQR------GGGAIVVVSSINGTRTFTTPGATAYTATKAAQVAIVQQLALELGKH 201 Query: 181 GVRVNAISAGPIRTLAASGIKDFRKM-----LAHCEAVTPI--RRTVTIEDVGNSAAFLC 233 +RVNA+ G I T + K + + + PI + EDV FL Sbjct: 202 HIRVNAVCPGAIETNISDNTKLRHEEETAIPVEWPKGQVPITDGQPGRSEDVAELIRFLV 261 Query: 234 SDLSAGISGEVVHVDGG 250 S+ + ++G V +DGG Sbjct: 262 SERARHVTGSPVWIDGG 278 >3F4B-A nrPDB Length = 323 Score = 156 bits (396), Expect = 7e-39, Method: Composition-based stats. Identities = 67/304 (22%), Positives = 132/304 (43%), Gaps = 62/304 (20%) Query: 10 LVTGVASKLSIAYGIAQAMHREGAELAF---------------TYQNDKLKGRVEEFAAQ 54 + GV +GIA+ + + ++ F + + DK + + + Sbjct: 11 FIAGVGDSNGYGWGIAKELSKRNVKVIFGVWPPVYNIFIKNLESGKFDKDMIINNDNSKR 70 Query: 55 LGSDIVLQCDVA--------------------EDASIDTMFAELGKVWPKFDGFVHSIGF 94 + VL D ++ SI+ + + + K VHS Sbjct: 71 MQILDVLPLDAGFDNYDDIDEDTKNNKRYNNLKNYSIEEVANLIYNKYGKISMLVHS--L 128 Query: 95 APGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIP 154 A G ++ ++ +R+G+ A SSYS +++ K +N G ++++L+Y +++ +P Sbjct: 129 ANGREVQKSLLD-TSRDGYLDAISKSSYSLISLCKHFCKFMNSGGSVVSLTYQASQKVVP 187 Query: 155 NYNV-MGLAKASLEANVRYMANAMG-PEGVRVNAISAGPIRTLAASGI------------ 200 Y M AKA+LE++ R +A +G +R+N ISAGP+++ AA+ I Sbjct: 188 GYGGGMSSAKAALESDTRVLAYYLGRKYNIRINTISAGPLKSRAATAINKFNNNQKNNMN 247 Query: 201 ----------KDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGG 250 + + E P+++ + DVG+ A+FL S S+ ++G+ ++VD G Sbjct: 248 SSGETDKQNYSFIDYAIDYSEKYAPLKKKLLSTDVGSVASFLLSKESSAVTGQTIYVDNG 307 Query: 251 FSIA 254 +I Sbjct: 308 LNIM 311 >4DA9-A nrPDB Length = 280 Score = 156 bits (396), Expect = 7e-39, Method: Composition-based stats. Identities = 50/239 (20%), Positives = 94/239 (39%), Gaps = 11/239 (4%) Query: 25 AQAMHREGAELAFTYQNDK--LKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVW 82 A+A+ G ++A T D + + E + I L+ D+A+ +S + + Sbjct: 46 ARALAASGFDIAITGIGDAEGVAPVIAELSGLGARVIFLRADLADLSSHQATVDAVVAEF 105 Query: 83 PKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSML-----NP 137 + D V++ G A + D + E F ++ V +A + Sbjct: 106 GRIDCLVNNAGIASIVR---DDFLDLKPENFDTIVGVNLRGTVFFTQAVLKAMLASDARA 162 Query: 138 GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAA 197 +++ ++ + A P ++KA L A + +A + G+ V + G IR+ Sbjct: 163 SRSIINITSVSAVMTSPERLDYCMSKAGLAAFSQGLALRLAETGIAVFEVRPGIIRSDMT 222 Query: 198 SGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAM 256 + + L + P+RR ED+GN A L +G V+ DGG SI + Sbjct: 223 AAVSGKYDGLIE-SGLVPMRRWGEPEDIGNIVAGLAGGQFGFATGSVIQADGGLSIGRL 280 >3U4C-A nrPDB Length = 281 Score = 156 bits (394), Expect = 1e-38, Method: Composition-based stats. Identities = 47/259 (18%), Positives = 99/259 (38%), Gaps = 23/259 (8%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN-DKLKGRVEEFAAQLGSD--IVLQC 63 + V G + I IA + + L +N D ++ E+ A+ IVL Sbjct: 24 RTAFVMGASQ--GIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVLAG 81 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSI-GFAPGDQLDGDYVNAVTREGFKIAHDISSY 122 D+++ + +F ++ + D +++I G AP D + E + Sbjct: 82 DMSDQHTRAGIFQKIESQCGRLDVLINNIPGGAP------DTFDNCNIEDMTATFTQKTV 135 Query: 123 SFVAMAKACRSMLNPG--SALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 +++ K S++ ++ + + N + A+L + ++ + P Sbjct: 136 AYIDAIKRASSLMKQNEFGRIINIVGNLWKEPGANMFTNSMMNAALINASKNISIQLAPH 195 Query: 181 GVRVNAISAGPIRTL---------AASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAF 231 + VN ++ G I T +K + P++R + E+ AAF Sbjct: 196 NITVNCLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGIPMKRVGSAEETAALAAF 255 Query: 232 LCSDLSAGISGEVVHVDGG 250 L S+ ++ I+G+ + DGG Sbjct: 256 LASEEASYITGQQISADGG 274 >2O2Y-A nrPDB Length = 349 Score = 153 bits (388), Expect = 6e-38, Method: Composition-based stats. Identities = 68/327 (20%), Positives = 137/327 (41%), Gaps = 81/327 (24%) Query: 10 LVTGVASKLSIAYGIAQAMHREGAELAF------------TYQNDK-------LKGRVEE 50 + G+ +GIA+ + + ++ F Y+N K K + Sbjct: 18 FIAGIGDTNGYGWGIAKELSKRNVKIIFGIWPPVYNIFMKNYKNGKFDNDMIIDKDKKMN 77 Query: 51 FAAQLGSDIVL--------------QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAP 96 L D + ++ ++ +I+ + + + + K + VHS A Sbjct: 78 ILDMLPFDASFDTANDIDEETKNNKRYNMLQNYTIEDVANLIHQKYGKINMLVHS--LAN 135 Query: 97 GDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNY 156 ++ D +N +R+G+ A SSYS +++ K +++ P S++++L+Y +++ +P Y Sbjct: 136 AKEVQKDLLN-TSRKGYLDALSKSSYSLISLCKYFVNIMKPQSSIISLTYHASQKVVPGY 194 Query: 157 -NVMGLAKASLEANVRYMANAMGP-EGVRVNAISAGPIRTLAASGIKDF----------- 203 M AKA+LE++ R +A +G +R+N ISAGP+++ AA+ I Sbjct: 195 GGGMSSAKAALESDTRVLAYHLGRNYNIRINTISAGPLKSRAATAINKLNNTYENNTNQN 254 Query: 204 --------------------------------RKMLAHCEAVTPIRRTVTIEDVGNSAAF 231 + + E P+R+ + D+G+ A+F Sbjct: 255 KNRNSHDVHNIMNNSGEKEEKKNSASQNYTFIDYAIEYSEKYAPLRQKLLSTDIGSVASF 314 Query: 232 LCSDLSAGISGEVVHVDGGFSIAAMNE 258 L S S I+G+ ++VD G +I + + Sbjct: 315 LLSRESRAITGQTIYVDNGLNIMFLPD 341 >2GDZ-A nrPDB Length = 267 Score = 146 bits (369), Expect = 9e-36, Method: Composition-based stats. Identities = 43/218 (19%), Positives = 82/218 (37%), Gaps = 25/218 (11%) Query: 6 GKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQ---LGSDIVLQ 62 GK LVTG A I A+A+ +GA++A N + + + + + +Q Sbjct: 7 GKVALVTGAAQ--GIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLFIQ 64 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSY 122 CDVA+ + F ++ + + D V++ G + ++ I+ Sbjct: 65 CDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN-------------NEKNWEKTLQINLV 111 Query: 123 SFVAMAKACRSMLNP-----GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRY--MAN 175 S ++ ++ G ++ +S L + V +K + R +A Sbjct: 112 SVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAA 171 Query: 176 AMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAV 213 + GVR+NAI G + T I+ M + E Sbjct: 172 NLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYK 209 >4TRR-A nrPDB Length = 269 Score = 145 bits (366), Expect = 2e-35, Method: Composition-based stats. Identities = 56/267 (20%), Positives = 100/267 (37%), Gaps = 21/267 (7%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN-DKLKGRVEEFAAQLGSDI 59 M L+GK +VTG AS I IA + + GA +A N D +E G I Sbjct: 9 MSNLNGKTAVVTGAAS--GIGKEIALELAKAGAAVAIADLNQDGANAVADEINKAGGKAI 66 Query: 60 VLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDI 119 + DV + +++T ++ + + D V + G + ++ + +K I Sbjct: 67 GVAMDVTNEEAVNTGIDKVAEAFGSVDILVSNAGIQIVNPIEN-----YSFADWKKMQAI 121 Query: 120 SSYSFVAMAKACRSML---NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANA 176 KA + + G ++ + + + A P + AK L R +A Sbjct: 122 HVDGAFLTTKAALKHMYKDDRGGVVIYMGSVHSHEASPLKSAYVTAKHGLLGLARVLAKE 181 Query: 177 MGPEGVRVNAISAGPIRTLAAS----------GIKDFRKMLAHCEAVTPIRRTVTIEDVG 226 VR + + G +RT GI + + T T++DV Sbjct: 182 GAKHNVRSHVVCPGFVRTPLVDKQIPEQAKELGISEEEVIKKVMLGNTVDGVFTTVQDVA 241 Query: 227 NSAAFLCSDLSAGISGEVVHVDGGFSI 253 + FL + SA ++G+ V G+ + Sbjct: 242 QTVLFLSAFPSAALTGQSFIVSHGWFM 268 >4CR6-A nrPDB Length = 271 Score = 144 bits (363), Expect = 4e-35, Method: Composition-based stats. Identities = 60/267 (22%), Positives = 103/267 (38%), Gaps = 16/267 (5%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVL 61 G L+GK +VTG A I +A REGA + +L E I + Sbjct: 11 GRLAGKAAIVTGAAG--GIGRATVEAYLREGASVVAMDLAPRLAATRYEE----PGAIPI 64 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 CD+A+ A+ID A+ D V G G++++ + + + Sbjct: 65 ACDLADRAAIDAAMADAVARLGGLDILVAGGALKGGT---GNFLDLSDADWDRYVDVNMT 121 Query: 122 YSFVAMAKACRSMLNPGS-------ALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMA 174 +F+ R+M+ G+ ++T+ + + A P AK + R MA Sbjct: 122 GTFLTCRAGARAMVAAGAGKDGRSARIITIGSVNSFMAEPEAAAYVAAKGGVAMLTRAMA 181 Query: 175 NAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCS 234 + G+ VN I+ GP+ + ++ + R E+V +A FL Sbjct: 182 VDLARHGILVNMIAPGPVDVTGNNTGYSEPRLAEQVLDEVALGRPGLPEEVATAAVFLAE 241 Query: 235 DLSAGISGEVVHVDGGFSIAAMNELEL 261 D S+ I+G + +DGG S + Sbjct: 242 DGSSFITGSTITIDGGLSAMIFGGMRE 268 >3PXX-A nrPDB Length = 287 Score = 143 bits (362), Expect = 6e-35, Method: Composition-based stats. Identities = 55/287 (19%), Positives = 94/287 (32%), Gaps = 46/287 (16%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAF-------------TYQNDKLKGR 47 MG + K +LVTG A A + EGA++ + L+ Sbjct: 5 MGRVQDKVVLVTGGA--RGQGRSHAVKLAEEGADIILFDICHDIETNEYPLATSRDLEEA 62 Query: 48 VEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNA 107 E + DV + A++ A + K D V + G P Sbjct: 63 GLEVEKTGRKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANAGICPLGA-------H 115 Query: 108 VTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGA-----------ERAIPNY 156 + + F A D+ + A L G++++T + P Sbjct: 116 LPVQAFADAFDVDFVGVINTVHAALPYLTSGASIITTGSVAGLIAAAQPPGAGGPQGPGG 175 Query: 157 NVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVT-- 214 AK +++ +A + P+ +R N I + T + +R+ EA + Sbjct: 176 AGYSYAKQLVDSYTLQLAAQLAPQSIRANVIHPTNVNTDMLNSAPMYRQFRPDLEAPSRA 235 Query: 215 ------PIRR-----TVTIEDVGNSAAFLCSDLSAGISGEVVHVDGG 250 P + V D+ N+ FL SD S ++G VD G Sbjct: 236 DALLAFPAMQAMPTPYVEASDISNAVCFLASDESRYVTGLQFKVDAG 282 >3ZV3-A nrPDB Length = 281 Score = 139 bits (352), Expect = 7e-34, Method: Composition-based stats. Identities = 53/264 (20%), Positives = 98/264 (37%), Gaps = 17/264 (6%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 L+G+ L+TG AS + + EGA +A ++ + +E A G+ + + Sbjct: 3 LTGEVALITGGAS--GLGRALVDRFVAEGARVAVLDKSAERLRELE--VAHGGNAVGVVG 58 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 DV + K D + + G D F ++ Sbjct: 59 DVRSLQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDIFHVNVKG 118 Query: 124 FVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 ++ KAC L + GS + T+S + K ++ VR MA + P Sbjct: 119 YIHAVKACLPALVSSRGSVVFTISN-AGFYPNGGGPLYTATKHAVVGLVRQMAFELAPH- 176 Query: 182 VRVNAISAGPIRTLA----ASGIKDFR----KMLAHCEAVTPIRRTVTIEDVGNSAAFLC 233 VRVN ++ G + T + G+ + + ++V PI R +E+ + F Sbjct: 177 VRVNGVAPGGMNTDLRGPSSLGLSEQSISSVPLADMLKSVLPIGRMPALEEYTGAYVFFA 236 Query: 234 S-DLSAGISGEVVHVDGGFSIAAM 256 + S +G +++ DGG + Sbjct: 237 TRGDSLPATGALLNYDGGMGVRGF 260 >5IZ4-A nrPDB Length = 271 Score = 138 bits (349), Expect = 2e-33, Method: Composition-based stats. Identities = 44/261 (16%), Positives = 96/261 (36%), Gaps = 19/261 (7%) Query: 8 RILVTGVASKLSIAYGIAQAMHREGAELAFTYQND---KLKGRVEEFAAQLGS-DIVLQC 63 ++TG AS I A + G +A +D VE G+ ++ Sbjct: 16 VCVITGSAS--GIGAATALRFAQAGWSVAIGNFDDSTRDAASTVEALCRDAGAQTLIFDA 73 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 DV +DA + W + D ++ G + + + + F+ + ++ Sbjct: 74 DVGKDADCRHAVDMVASRWQRIDALINCAGTTRV--IPHNAFDQIDDFEFERVYRVNLIG 131 Query: 124 FVAMAKACRSMLNPGSA------LLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAM 177 M +A +L ++ ++ +S L + +K ++ +A + Sbjct: 132 LYQMTRAAVPLLRESASATRSTSVVNVSSLAGLNGTGSSIAYAASKGAVNTLTLSLARNL 191 Query: 178 GPEGVRVNAISAGPIRTLAASGIKDFRK---MLAHCEAVTPIRRTVTIEDVGNSAAFLCS 234 P +RVNA++ G + + D +L+ P++R ++ A FL + Sbjct: 192 APH-IRVNALAPGMVDDGLLLRVLDAAAYDGVLSRMTESAPLKRVSRPAEIAELAWFL-T 249 Query: 235 DLSAGISGEVVHVDGGFSIAA 255 + I+G+V+ + G + Sbjct: 250 AHAPAITGQVIAAENGLLLGG 270 >1BDB-A nrPDB Length = 277 Score = 136 bits (342), Expect = 1e-32, Method: Composition-based stats. Identities = 55/265 (20%), Positives = 99/265 (37%), Gaps = 19/265 (7%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV-LQ 62 L G+ +L+TG AS + + EGA++A DK R+ E G +++ + Sbjct: 3 LKGEAVLITGGAS--GLGRALVDRFVAEGAKVAV---LDKSAERLAELETDHGDNVLGIV 57 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSY 122 DV + + K D + + G D F I+ Sbjct: 58 GDVRSLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHINVK 117 Query: 123 SFVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 ++ KAC L + G+ + T+S + AK ++ VR +A + P Sbjct: 118 GYIHAVKACLPALVASRGNVIFTISN-AGFYPNGGGPLYTAAKHAIVGLVRELAFELAPY 176 Query: 181 GVRVNAISAGPIRTL--------AASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFL 232 VRVN + +G I + S + ++V PI R +E+ + F Sbjct: 177 -VRVNGVGSGGINSDLRGPSSLGMGSKAISTVPLADMLKSVLPIGRMPEVEEYTGAYVFF 235 Query: 233 CS-DLSAGISGEVVHVDGGFSIAAM 256 + +A +G +++ DGG + Sbjct: 236 ATRGDAAPATGALLNYDGGLGVRGF 260 >4RGB-A nrPDB Length = 294 Score = 129 bits (326), Expect = 1e-30, Method: Composition-based stats. Identities = 47/278 (16%), Positives = 89/278 (32%), Gaps = 34/278 (12%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFT-------------YQNDKLKGR 47 MG L G+ + +TG A A +GA + ++L+ Sbjct: 20 MGSLDGRVVFITGAA--RGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEET 77 Query: 48 VEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNA 107 + + DV + A + +F + + D + + G + + D Sbjct: 78 ARLVEKTGQEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLTNPDERDAS-- 135 Query: 108 VTREGFKIAHDISSYSFVAMAKACRSMLN---PGSALLTLSYLGAER----AIPNYNVMG 160 E ++ DI + + G L+ S + A + Sbjct: 136 ---EALRLGLDIMLIGVWNTFQVAIPHMKERGQGGNLIATSSMIALLDLTDGRGGTDAYL 192 Query: 161 LAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAA-------SGIKDFRKMLAHCEAV 213 +K ++ VR A + + +RVN ++ T I++ ++ Sbjct: 193 TSKLAITGLVRSYALMLAADRIRVNGVAPTNCSTPMITENPALFKVIEENPHLVNAMSTA 252 Query: 214 TPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGF 251 P + DV N+ FL SD +G V+ VD G Sbjct: 253 LPDFPMIEPRDVSNAILFLISDAGRSFTGSVLKVDAGM 290 >5O3Z-A nrPDB Length = 263 Score = 128 bits (321), Expect = 4e-30, Method: Composition-based stats. Identities = 36/260 (13%), Positives = 96/260 (36%), Gaps = 23/260 (8%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQ---LGSDIVLQC 63 + +V G L + + + + G +A N+ R+ + G + Sbjct: 7 QVAVVIGGGQTLG--AFLCEGLAQAGYHVAVADLNESNANRLADTINSRYGAGRAYGFKV 64 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 D ++AS++ + + + + + D V+S G A + F ++ ++ Sbjct: 65 DATDEASVEALARAVDETFGRADLLVYSAGVAKAAP-----ITQFRLTDFDLSLQVNLVG 119 Query: 124 FVAMAKACRSML---NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE 180 + ++ ++ ++ ++ + + + AK + +A + Sbjct: 120 YFLCSREFSKLMIRDGIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDLAEY 179 Query: 181 GVRVNAISAG-PIRTLAASGIKD---------FRKMLAHCEAVTPIRRTVTIEDVGNSAA 230 G+ V+++ G +++ + ++ + P++R +DV N Sbjct: 180 GITVHSLMLGNLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPLKRGCDYQDVLNVLL 239 Query: 231 FLCSDLSAGISGEVVHVDGG 250 F SD +A +G+ ++V GG Sbjct: 240 FYASDKAAYCTGQSINVTGG 259 >1E3W-A nrPDB Length = 261 Score = 127 bits (320), Expect = 4e-30, Method: Composition-based stats. Identities = 39/258 (15%), Positives = 87/258 (33%), Gaps = 16/258 (6%) Query: 5 SGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCD 64 G ++TG AS + A+ + +GA + E G+ I + Sbjct: 9 KGLVAVITGGAS--GLGLSTAKRLVGQGATAVLLDVPNSEGET--EAKKLGGNCIFAPAN 64 Query: 65 VAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAV-TREGFKIAHDISSYS 123 V + + + + + D V+ G A + + N V T E F+ +++ Sbjct: 65 VTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIG 124 Query: 124 FVAMAKACRSMLNPG--------SALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMAN 175 + + ++ ++ + + A +K + +A Sbjct: 125 TFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIAR 184 Query: 176 AMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSD 235 + P G+RV I+ G T + + D + + P R + + + Sbjct: 185 DLAPIGIRVVTIAPGLFATPLLTTLPDTVRNFLASQVPFPS-RLGDPAEYAHLVQMVI-- 241 Query: 236 LSAGISGEVVHVDGGFSI 253 + ++GEV+ +DG + Sbjct: 242 ENPFLNGEVIRLDGAIRM 259 >2O23-A nrPDB Length = 265 Score = 123 bits (310), Expect = 6e-29, Method: Composition-based stats. Identities = 39/260 (15%), Positives = 86/260 (33%), Gaps = 20/260 (7%) Query: 5 SGKRILVTGVASKLSIAYGIAQAMHREGA-ELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 G ++TG AS + A+ + +GA + N + + ++ + + Sbjct: 11 KGLVAVITGGAS--GLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL---GNNCVFAPA 65 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFA-PGDQLDGDYVNAVTREGFKIAHDISSY 122 DV + + T A + + D V+ G A + T E F+ D++ Sbjct: 66 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 125 Query: 123 SFVAMAKACRSMLNPG--------SALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMA 174 + + + ++ + + A +K + +A Sbjct: 126 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 185 Query: 175 NAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIR-RTVTIEDVGNSAAFLC 233 + P G+RV I+ G T + + K+ + P R + + Sbjct: 186 RDLAPIGIRVMTIAPGLFGTPLLTSL--PEKVCNFLASQVPFPSRLGDPAEYAHLVQ--A 241 Query: 234 SDLSAGISGEVVHVDGGFSI 253 + ++GEV+ +DG + Sbjct: 242 IIENPFLNGEVIRLDGAIRM 261 >3UCF-A nrPDB Length = 223 Score = 119 bits (299), Expect = 1e-27, Method: Composition-based stats. Identities = 53/249 (21%), Positives = 95/249 (38%), Gaps = 35/249 (14%) Query: 8 RILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAE 67 +V G S I +A+ + E + + L D+++ Sbjct: 8 VYVVLGGTS--GIGAELAKQLESEHTIVHVASRQTGL-------------------DISD 46 Query: 68 DASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAM 127 + S+ F + FD + + G V V K A D + V Sbjct: 47 EKSVYHYFETI----GAFDHLIVTAGSYA----PAGKVVDVEVTQAKYAFDTKFWGAVLA 98 Query: 128 AKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAI 187 AK L G ++ S + + + + N V A++EA + +A + P +RVNAI Sbjct: 99 AKHGARYLKQGGSITLTSGMLSRKVVANTYVKAAINAAIEATTKVLAKELAP--IRVNAI 156 Query: 188 SAGPIRTLAASGI--KDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVV 245 S G +T A G+ D M ++ P+ + D+ A+L + ++ ++G V+ Sbjct: 157 SPGLTKTEAYKGMNADDRDAMYQRTQSHLPVGKVGEASDIA--MAYLFAIQNSYMTGTVI 214 Query: 246 HVDGGFSIA 254 VDGG + Sbjct: 215 DVDGGALLG 223 >3OML-A nrPDB Length = 613 Score = 118 bits (296), Expect = 3e-27, Method: Composition-based stats. Identities = 34/252 (13%), Positives = 65/252 (25%), Gaps = 38/252 (15%) Query: 5 SGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN----------DKLKGRVEEFAAQ 54 G+ +VTG + A GA++ V+E Sbjct: 18 DGRVAVVTGA--GAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRKA 75 Query: 55 LGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFK 114 G + V + A + K + + D V++ G L + + + + Sbjct: 76 GGEAVADYNSVIDGAKV---IETAIKAFGRVDILVNNAGI-----LRDRSLVKTSEQDWN 127 Query: 115 IAHDISSYSFVAMAKACRSMLNPG--SALLTLSYLGAERAIPNYNVMGLAKASLEANVRY 172 + +D+ +A + ++ S AK L Sbjct: 128 LVNDVHLKGSFKCTQAAFPYMKKQNYGRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLANT 187 Query: 173 MANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFL 232 +A V N I + GI + + + A+L Sbjct: 188 VAIEGARNNVLCNVIVPTA-ASRMTEGILPDILFNE-----------LKPKLIAPVVAYL 235 Query: 233 ----CSDLSAGI 240 C D + I Sbjct: 236 CHESCEDNGSYI 247 >5ILO-A nrPDB Length = 271 Score = 116 bits (291), Expect = 9e-27, Method: Composition-based stats. Identities = 39/203 (19%), Positives = 73/203 (35%), Gaps = 14/203 (6%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGA-ELAFTYQNDKLKGRVEEFAAQL-GSDIVL 61 GK +VTG A I +++ + GA ++A D L+ V+ AA S +++ Sbjct: 13 FRGKNAVVTGGAG--GIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMII 70 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 + DVA ++ + E+ K + D V+ G V + + Sbjct: 71 KMDVANKKGVEATYEEIAKTFGNIDIVVNVAGIFNDK-----DVQRTLLVNLGGIINSTL 125 Query: 122 YSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANA--MGP 179 + M K G ++ +S + + V G KA + R +AN Sbjct: 126 SALPYMGKDNG---GKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQR 182 Query: 180 EGVRVNAISAGPIRTLAASGIKD 202 G++ + G T + + Sbjct: 183 SGIKFVTVCPGATMTDMFTNFTE 205 >4DRY-A nrPDB Length = 281 Score = 114 bits (285), Expect = 4e-26, Method: Composition-based stats. Identities = 38/217 (17%), Positives = 74/217 (34%), Gaps = 13/217 (5%) Query: 24 IAQAMHREGAELAFTYQN-DKLKGRVEEFAAQLGSDI-VLQCDVAEDASIDTMFAELGKV 81 IAQA+ EG + T + D L E + G+ + + CDV + + +FA + Sbjct: 49 IAQALSAEGYSVVITGRRPDVLDAAAGEIGGRTGNIVRAVVCDVGDPDQVAALFAAVRAE 108 Query: 82 WPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLN----P 137 + + D V++ G + + VT E + + + M+ Sbjct: 109 FARLDLLVNNAG----SNVPPVPLEEVTFEQWNGIVAANLTGAFLCTQHAFRMMKAQTPR 164 Query: 138 GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAA 197 G ++ + A+ PN K ++ + A + I G T Sbjct: 165 GGRIINNGSISAQTPRPNSAPYTATKHAITGLTKSTALDGRMHDIACGQIDIGNAATDMT 224 Query: 198 SGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCS 234 + + A P T+ IE + + ++ S Sbjct: 225 ARMSTGVLQANGEVAAEP---TIPIEHIAEAVVYMAS 258 >3PPI-A nrPDB Length = 281 Score = 113 bits (284), Expect = 6e-26, Method: Composition-based stats. Identities = 48/256 (18%), Positives = 92/256 (35%), Gaps = 19/256 (7%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDI-VLQ 62 G +V+G A + + +H +G + D + + A +LG+ + Sbjct: 28 FEGASAIVSGGAG--GLGEATVRRLHADGLGVVIA---DLAAEKGKALADELGNRAEFVS 82 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFA--------PGDQLDGDYVNAVTREGFK 114 +V + S+ ++ V GF G D Sbjct: 83 TNVTSEDSVLAAIEAANQLGRLRYAVVAHGGFGVAQRIVQRDGSPADMGGFTKTIDLYLN 142 Query: 115 IAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMA 174 ++++ ++A A AL+ + + AKA + A Sbjct: 143 GTYNVARLVAASIAAAEPRENGERGALVLTASIAGYEGQIGQTAYAAAKAGVIGLTIAAA 202 Query: 175 NAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPI-RRTVTIEDVGNSAAFLC 233 + G+RVN I+ G ++T + + LA A P +R T ++ ++AAFL Sbjct: 203 RDLSSAGIRVNTIAPGTMKTPIMESVG--EEALAKFAANIPFPKRLGTPDEFADAAAFLL 260 Query: 234 SDLSAGISGEVVHVDG 249 ++ I+GEV+ +DG Sbjct: 261 TN--GYINGEVMRLDG 274 >3RKU-A nrPDB Length = 287 Score = 113 bits (284), Expect = 6e-26, Method: Composition-based stats. Identities = 38/237 (16%), Positives = 86/237 (36%), Gaps = 16/237 (6%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREG-AELAFTYQN-DKLKGRVEEFAAQLGSD-- 58 L+ K +L+TG ++ + A + G +L + +KL+ + + + Sbjct: 30 RLAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPNAKV 89 Query: 59 IVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHD 118 V Q D+ + I L + + D V++ G L D V + E + D Sbjct: 90 HVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAG----KALGSDRVGQIATEDIQDVFD 145 Query: 119 ISSYSFVAMAKACRSM--LNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANA 176 + + + + +A + ++ L + A P ++ +K ++ A + Sbjct: 146 TNVTALINITQAVLPIFQAKNSGDIVNLGSIAGRDAYPTGSIYCASKFAVGAFTDSLRKE 205 Query: 177 MGPEGVRVNAISAGPIRTL--AASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAF 231 + +RV I+ G + T + + + TP+ +DV + + Sbjct: 206 LINTKIRVILIAPGLVETEFSLVRYRGNEEQAKNVYKDTTPL----MADDVADLIVY 258 >2NWQ-A nrPDB Length = 272 Score = 106 bits (265), Expect = 9e-24, Method: Composition-based stats. Identities = 37/227 (16%), Positives = 75/227 (33%), Gaps = 15/227 (6%) Query: 10 LVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDA 69 +TG S A+ G L T + ++ + + + L DV + A Sbjct: 25 FITGATS--GFGEACARRFAEAGWSLVLTGRREERLQALAGELSAKTRVLPLTLDVRDRA 82 Query: 70 SIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAK 129 ++ L + + G +++ G A L D + + + D + + + Sbjct: 83 AMSAAVDNLPEEFATLRGLINNAGLA----LGTDPAQSCDLDDWDTMVDTNIKGLLYSTR 138 Query: 130 ACRSML---NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNA 186 L G++++ L + + P +V G KA +E + + GVRV Sbjct: 139 LLLPRLIAHGAGASIVNLGSVAGKWPYPGSHVYGGTKAFVEQFSLNLRCDLQGTGVRVTN 198 Query: 187 ISAGPIRTL--AASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAF 231 + G + D + PI ED+ + + Sbjct: 199 LEPGLCESEFSLVRFGGDQARYDKTYAGAHPI----QPEDIAETIFW 241 >2HRB-A nrPDB Length = 274 Score = 105 bits (262), Expect = 2e-23, Method: Composition-based stats. Identities = 40/239 (16%), Positives = 77/239 (32%), Gaps = 58/239 (24%) Query: 7 KRILVTGVASKLSIAYGIAQAMHRE--GAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCD 64 + LVTG I IA+ + R+ G + + + V++ A+ S Q D Sbjct: 3 RVALVTGA--NRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLD 60 Query: 65 VAEDASIDTMFAELGKVWPKFDGFVHSIGFA--PGDQLDGDYVNAVTREGFKIAHDISSY 122 + + SI + L K + + V++ A D + D +T + + Sbjct: 61 IDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMT-------LKTNFF 113 Query: 123 SFVAMAKACRSMLNPGSALLTLSYLGAERAIPN--------------------------- 155 + M ++ P ++ +S L RA N Sbjct: 114 ATRNMCNELLPIMKPHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFV 173 Query: 156 --------------YNVMGLAKASLEANVRYMANAMGPE----GVRVNAISAGPIRTLA 196 + G++K + R +A + + + VNA GP++T Sbjct: 174 EDTKNEVHEREGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDM 232 >3KZV-A nrPDB Length = 254 Score = 104 bits (259), Expect = 5e-23, Method: Composition-based stats. Identities = 41/199 (20%), Positives = 77/199 (38%), Gaps = 11/199 (5%) Query: 6 GKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV-LQCD 64 GK ILVTGV+ I I + + Y + + +++ + G + D Sbjct: 2 GKVILVTGVS--RGIGKSIVDVLFSLDKDTVV-YGVARSEAPLKKLKEKYGDRFFYVVGD 58 Query: 65 VAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSF 124 + ED+ + + K K D V + G Q VN + +K +DI+ +S Sbjct: 59 ITEDSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQ----NVNEIDVNAWKKLYDINFFSI 114 Query: 125 VAMAKACRSMLNP-GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVR 183 V++ L ++ +S ++ G +KA+L +AN V+ Sbjct: 115 VSLVGIALPELKKTNGNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANE--ERQVK 172 Query: 184 VNAISAGPIRTLAASGIKD 202 A++ G + T I++ Sbjct: 173 AIAVAPGIVDTDMQVNIRE 191 >1A27-A nrPDB Length = 289 Score = 99.5 bits (247), Expect = 1e-21, Method: Composition-based stats. Identities = 49/249 (19%), Positives = 91/249 (36%), Gaps = 35/249 (14%) Query: 8 RILVTGVASKLSIAYGIAQAMHR---EGAELAFTYQNDKLKGRVEEFAAQL----GSDIV 60 +L+TG +S I +A + + ++ T ++ K +GR+ E A L GS Sbjct: 4 VVLITGCSS--GIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 61 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 LQ DV + S+ + + + D V + G L+ A+ + D++ Sbjct: 62 LQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLE-----ALGEDAVASVLDVN 114 Query: 121 SYSFVAMAKACRSMLNPGSA--LLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMG 178 V M +A + + +L +G +P +V +K +LE +A + Sbjct: 115 VVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLL 174 Query: 179 PEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVT---------------IE 223 P GV ++ I GP+ T + + + + R E Sbjct: 175 PFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPE 234 Query: 224 DVGNSAAFL 232 +V FL Sbjct: 235 EVAEV--FL 241 >6CGE-A nrPDB Length = 328 Score = 98.8 bits (245), Expect = 2e-21, Method: Composition-based stats. Identities = 49/249 (19%), Positives = 91/249 (36%), Gaps = 35/249 (14%) Query: 8 RILVTGVASKLSIAYGIAQAMHR---EGAELAFTYQNDKLKGRVEEFAAQL----GSDIV 60 +L+TG +S I +A + + ++ T ++ K +GR+ E A L GS Sbjct: 5 VVLITGCSS--GIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLET 62 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 LQ DV + S+ + + + D V + G L+ A+ + D++ Sbjct: 63 LQLDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLE-----ALGEDAVASVLDVN 115 Query: 121 SYSFVAMAKACRSMLNPGSA--LLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMG 178 V M +A + + +L +G +P +V +K +LE +A + Sbjct: 116 VVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLL 175 Query: 179 PEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVT---------------IE 223 P GV ++ I GP+ T + + + + R E Sbjct: 176 PFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPE 235 Query: 224 DVGNSAAFL 232 +V FL Sbjct: 236 EVAEV--FL 242 >1FJH-A nrPDB Length = 257 Score = 98.4 bits (244), Expect = 3e-21, Method: Composition-based stats. Identities = 52/275 (18%), Positives = 95/275 (34%), Gaps = 62/275 (22%) Query: 9 ILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAED 68 I+++G A+ I + + G ++ D + D++ Sbjct: 4 IVISGCAT--GIGAATRKVLEAAGHQIVGIDIRDAE----------------VIADLSTA 45 Query: 69 ASIDTMFAELGKVWP-KFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAM 127 A++ DG V G P ++ G+ V ++ + + Sbjct: 46 EGRKQAIADVLAKCSKGMDGLVLCAGLGPQTKVLGNVV------------SVNYFGATEL 93 Query: 128 AKACRSMLNPGS--ALLTLSYLGAE---------------------RAIPNYN------- 157 A L G A + +S + + RAI + Sbjct: 94 MDAFLPALKKGHQPAAVVISSVASAHLAFDKNPLALALEAGEEAKARAIVEHAGEQGGNL 153 Query: 158 VMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRT-LAASGIKDFRKMLAHCEAVTPI 216 +K +L VR A A G GVR+N I+ G T L +G++D R + + V P+ Sbjct: 154 AYAGSKNALTVAVRKRAAAWGEAGVRLNTIAPGATETPLLQAGLQDPRYGESIAKFVPPM 213 Query: 217 RRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGF 251 R ++ + AFL S ++ + G + +DGG Sbjct: 214 GRRAEPSEMASVIAFLMSPAASYVHGAQIVIDGGI 248 >3DWF-A nrPDB Length = 276 Score = 98.4 bits (244), Expect = 3e-21, Method: Composition-based stats. Identities = 35/201 (17%), Positives = 77/201 (38%), Gaps = 14/201 (6%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV-- 60 L GK+++VTG + I IA + + GA + T ++ + +V +LG+ Sbjct: 8 MLQGKKVIVTGASK--GIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASAHY 65 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 + + + + AE G + D + + ++ + + +++ Sbjct: 66 IAGSMEDMTFAEEFVAEAGNLMGGLDMLILNHVLYNRLTFFHGEID-----NVRKSMEVN 120 Query: 121 SYSFVAMAKACRSM-LNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 +SFV ++ A M + ++ +S + + P +K +L+ + + Sbjct: 121 FHSFVVLSVAAMPMLMQSQGSIAVVSSVAGKITYPLIAPYSASKFALDGFFSTLRSEFLV 180 Query: 180 EGVRVN---AISAGPIRTLAA 197 V V+ I G I T A Sbjct: 181 NKVNVSITLCIL-GLIDTETA 200 >2DKN-A nrPDB Length = 255 Score = 98.4 bits (244), Expect = 3e-21, Method: Composition-based stats. Identities = 47/274 (17%), Positives = 84/274 (30%), Gaps = 60/274 (21%) Query: 8 RILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAE 67 I +TG AS I + + + R G + + ++ D++ Sbjct: 3 VIAITGSAS--GIGAALKELLARAGHTVIGIDRGQAD----------------IEADLST 44 Query: 68 DASIDTMFAELGKVWPK-FDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVA 126 +T A + DG V G VT + ++ + A Sbjct: 45 PGGRETAVAAVLDRCGGVLDGLVCCAGV------------GVTAANSGLVVAVNYFGVSA 92 Query: 127 MAKACRSMLNPGS--ALLTLSYLGAERAIPN--------------------------YNV 158 + L+ G A + + + A + + Sbjct: 93 LLDGLAEALSRGQQPAAVIVGSIAATQPGAAELPMVEAMLAGDEARAIELAEQQGQTHLA 152 Query: 159 MGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIK-DFRKMLAHCEAVTPIR 217 +K ++ R GVR+N ++ G + T K D R + V P+ Sbjct: 153 YAGSKYAVTCLARRNVVDWAGRGVRLNVVAPGAVETPLLQASKADPRYGESTRRFVAPLG 212 Query: 218 RTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGF 251 R +V + AFL ++ I G V+ VDGG Sbjct: 213 RGSEPREVAEAIAFLLGPQASFIHGSVLFVDGGM 246 >1N5D-A nrPDB Length = 288 Score = 98.0 bits (243), Expect = 3e-21, Method: Composition-based stats. Identities = 38/237 (16%), Positives = 77/237 (32%), Gaps = 54/237 (22%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGA-ELAFTYQN-DKLKGRVEEFAAQLGSDIVLQCD 64 + LVTG I + I + + R+ A ++ T ++ + + V++ A+ S Q D Sbjct: 5 RVALVTGA--NKGIGFAIVRDLCRQFAGDVVLTARDVARGQAAVKQLQAEGLSPRFHQLD 62 Query: 65 VAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSF 124 + + SI + L K + D V++ A QLD + E + + Sbjct: 63 IIDLQSIRALCDFLRKEYGGLDVLVNNAAIA--FQLDNPTPFHIQAE---LTMKTNFMGT 117 Query: 125 VAMAKACRSMLNPGSALLTLSYLGAERAIP------------------------------ 154 + ++ P ++ +S RA+ Sbjct: 118 RNVCTELLPLIKPQGRVVNVSSTEGVRALNECSPELQQKFKSETITEEELVGLMNKFVED 177 Query: 155 -----------NYNVMGLAKASLEANVRYMANAM----GPEGVRVNAISAGPIRTLA 196 + + G+ K + R A + + + +NA G +RT Sbjct: 178 TKNGVHRKEGWSDSTYGVTKIGVSVLSRIYARKLREQRAGDKILLNACCPGWVRTDM 234 >5L51-A nrPDB Length = 324 Score = 94.9 bits (235), Expect = 4e-20, Method: Composition-based stats. Identities = 51/312 (16%), Positives = 99/312 (31%), Gaps = 90/312 (28%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEE-FAAQLGSD-----IV 60 + +VTG I + I + + +G + +++K E +LGS+ + Sbjct: 16 RYAVVTGA--NKGIGFEICKQLASKGITVILASRDEKRGIEARERLIKELGSEFGDYVVS 73 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYV--------------- 105 Q DVA+ AS+ + + + D V++ G G ++GD Sbjct: 74 QQLDVADPASVAALVDFIKTKFGSLDILVNNAGL-NGTYMEGDASVLNDYVEAEFKTFQS 132 Query: 106 ---------------NAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSA--LLTLSYLG 148 T E K + + Y + +A +L + ++ +S Sbjct: 133 GAAKTEPYHPKATGRLVETVEHAKECIETNYYGSKRVTEALIPLLQQSDSPRIVNVSSTL 192 Query: 149 AERAI-------------------------------------------PNYNVMGLAKAS 165 + P+++ ++KA+ Sbjct: 193 SSLVFQTNEWAKGVFSSEEGLTEEKLEEVLAEFLKDFIDGKQQEKQWPPHFSAYKVSKAA 252 Query: 166 LEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDV 225 L A R +A R+NA+ G +T + G F A A P++ + + Sbjct: 253 LNAYTRIIAKKYPSF--RINAVCPGYTKTDLSYGHGQFTDAEA---AEAPVKLALLPQG- 306 Query: 226 GNSAAFLCSDLS 237 G S F D + Sbjct: 307 GPSGCFFFRDEA 318 >3E9N-A nrPDB Length = 245 Score = 93.8 bits (232), Expect = 7e-20, Method: Composition-based stats. Identities = 36/229 (15%), Positives = 77/229 (33%), Gaps = 20/229 (8%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 L K +VTG + I I + + R+ + +N + + E + + Sbjct: 3 LKKKIAVVTGATGGMGI--EIVKDLSRD-HIVYALGRNPEHLAALAEIEGVEPIESDIVK 59 Query: 64 DVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYS 123 +V E+ +D + K D VH+ A ++ + + D++ Sbjct: 60 EVLEEGGVDKL-----KNLDHVDTLVHAAAVARDTTIEAG-----SVAEWHAHLDLNVIV 109 Query: 124 FVAMAKACRSMLNPGSA-LLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGV 182 +++ L S ++ ++ P + +K +L G+ Sbjct: 110 PAELSRQLLPALRAASGCVIYINSGAGNGPHPGNTIYAASKHALRGLADAFRKEEANNGI 169 Query: 183 RVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAF 231 RV+ +S GP T G+ D + E +++ N+ F Sbjct: 170 RVSTVSPGPTNTPMLQGLMDSQGTNFRPEIYI------EPKEIANAIRF 212 >5PGZ-A nrPDB Length = 276 Score = 93.4 bits (231), Expect = 1e-19, Method: Composition-based stats. Identities = 36/203 (17%), Positives = 77/203 (37%), Gaps = 16/203 (7%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV-- 60 L GK+++VTG + I +A + + GA + T ++++ +V +LG+ Sbjct: 15 MLQGKKVIVTGASK--GIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHY 72 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFV-HSIGFAPGDQLDGDYVNAVTREGFKIAHDI 119 + + + + + GK+ D + + I D + + ++ Sbjct: 73 IAGTMEDMTFAEQFIVKAGKLMGGLDMLILNHITQTSLSLFHDDIHSV------RRVMEV 126 Query: 120 SSYSFVAMAKACRSMLNP-GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMG 178 + S+V M+ A ML ++ +S L + P +K +L+ + + Sbjct: 127 NFLSYVVMSTAALPMLKQSNGSIAVISSLAGKMTQPMIAPYSASKFALDGFFSTIRTELY 186 Query: 179 PEGVRVN---AISAGPIRTLAAS 198 V V+ + G I T A Sbjct: 187 ITKVNVSITLCVL-GLIDTETAM 208 >3BHI-A nrPDB Length = 276 Score = 92.6 bits (229), Expect = 2e-19, Method: Composition-based stats. Identities = 35/238 (14%), Positives = 71/238 (29%), Gaps = 56/238 (23%) Query: 8 RILVTGVASKLSIAYGIAQAMHR--EGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDV 65 LVTG I I + + R G + + + V++ A+ S Q D+ Sbjct: 6 VALVTGG--NKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDI 63 Query: 66 AEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFV 125 + SI + L K + D V++ G A + ++ + + Sbjct: 64 DDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQA-----EVTMKTNFFGTR 118 Query: 126 AMAKACRSMLNPGSALLTLSYLGAER---------------------------------- 151 + ++ P ++ +S + + R Sbjct: 119 DVCTELLPLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDT 178 Query: 152 --------AIPNYNVMGLAKASLEANVRYMANAMGPE----GVRVNAISAGPIRTLAA 197 P+ + G+ K + R A + + + +NA G +RT A Sbjct: 179 KKGVHQKEGWPS-SAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMA 235 >1SNY-A nrPDB Length = 267 Score = 90.3 bits (223), Expect = 8e-19, Method: Composition-based stats. Identities = 35/208 (16%), Positives = 81/208 (38%), Gaps = 23/208 (11%) Query: 8 RILVTGVASKLSIAYGIAQA-MHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVA 66 IL+TG L + A + + L T +N + +E+ A + +L+ D+ Sbjct: 23 SILITGCNRGLGLGLVKALLNLPQPPQHLFTTCRNREQAKELEDLAKNHSNIHILEIDLR 82 Query: 67 EDASIDTMFAELGKV--WPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSF 124 + D + A++ V + ++ G AP + AV + ++ Sbjct: 83 NFDAYDKLVADIEGVTKDQGLNVLFNNAGIAPKSAR----ITAVRSQELLDTLQTNTVVP 138 Query: 125 VAMAKACRSMLNPGS-------------ALLTLSYL-GAERAI--PNYNVMGLAKASLEA 168 + +AKAC +L + A++ +S + G+ + +K++L A Sbjct: 139 IMLAKACLPLLKKAAKANESQPMGVGRAAIINMSSILGSIQGNTDGGMYAYRTSKSALNA 198 Query: 169 NVRYMANAMGPEGVRVNAISAGPIRTLA 196 + ++ + P+ + ++ G ++T Sbjct: 199 ATKSLSVDLYPQRIMCVSLHPGWVKTDM 226 >3O26-A nrPDB Length = 311 Score = 85.7 bits (211), Expect = 2e-17, Method: Composition-based stats. Identities = 42/298 (14%), Positives = 87/298 (29%), Gaps = 90/298 (30%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVL--QCD 64 + +VTG I + I + + G + T ++ E + V+ Q D Sbjct: 13 RCAVVTGG--NKGIGFEICKQLSSNGIMVVLTCRDVTKGHEAVEKLKNSNHENVVFHQLD 70 Query: 65 VAED-ASIDTMFAELGKVWPKFDGFVHSIGFA------------------PGDQL----D 101 V + A++ ++ + + K D V++ G A ++L + Sbjct: 71 VTDPIATMSSLADFIKTHFGKLDILVNNAGVAGFSVDADRFKAMISDIGEDSEELVKIYE 130 Query: 102 GDYVNAVTREGFKIA---HDISSYSFVAMAKACRSMLNPGSA--LLTLSYLGAER----- 151 + E +++A I+ ++ + +L + ++ +S Sbjct: 131 KPEAQELMSETYELAEECLKINYNGVKSVTEVLIPLLQLSDSPRIVNVSSSTGSLKYVSN 190 Query: 152 -------------------------------------AIPNYN-VMGLAKASLEANVRYM 173 P++ +KA L A R + Sbjct: 191 ETALEILGDGDALTEERIDMVVNMLLKDFKENLIETNGWPSFGAAYTTSKACLNAYTRVL 250 Query: 174 ANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAF 231 AN + VN + G ++T GI ++ E V A F Sbjct: 251 ANKIPKFQ--VNCVCPGLVKTEMNYGIGNYTAEEG-------------AEHVVRIALF 293 >4HBG-A nrPDB Length = 286 Score = 81.0 bits (199), Expect = 4e-16, Method: Composition-based stats. Identities = 38/274 (13%), Positives = 80/274 (29%), Gaps = 64/274 (23%) Query: 8 RILVTGVASKLSIAYGIAQAMHREGAELAF--TYQNDKLKGRVEEFAAQLGSDIVLQCDV 65 +VTG I I Q + ++G + + + ++ Q G QC + Sbjct: 6 VAIVTGAT--RGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAI 63 Query: 66 A----------------------EDASIDTMFAELGKVWPK---------FDGFVHSIGF 94 A + + ++ L K + ++ G Sbjct: 64 AIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL 123 Query: 95 APGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSA-------------L 141 T + +++ S V M C + + Sbjct: 124 TQESL-----SVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTI 178 Query: 142 LTLSYL--GAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIR-TLAAS 198 + +S + + +P +V +KA+L +A M P +R IS G ++ T Sbjct: 179 VNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQ 238 Query: 199 GIK-DFRKMLAHCEAVTPIRRTVT--IEDVGNSA 229 + + ++ML I + T ++ Sbjct: 239 NLPVEAKEMLERT-----IGASGTSAPAEIAEEV 267 >5WQO-A nrPDB Length = 234 Score = 79.5 bits (195), Expect = 1e-15, Method: Composition-based stats. Identities = 34/193 (17%), Positives = 75/193 (38%), Gaps = 11/193 (5%) Query: 8 RILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDI-VLQCDVA 66 +L+ G + I G+A A + GA++ + + ++ A + G + + D+ Sbjct: 8 NVLIVGAS--RGIGLGLADAFLQRGAQVFAVARRPQGSPGLQALAERAGERLQAVTGDLN 65 Query: 67 EDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVA 126 + + + LG+ + D + + G Q D ++A E ++ + + Sbjct: 66 QHDCAERIGEMLGER--RIDRLIVNAGIYGPQQQDVAEIDA---EQTAQLFLTNAIAPLR 120 Query: 127 MAKACRSMLNPGSALLTLSYLGAERAIPNYNV---MGLAKASLEANVRYMANAMGPEGVR 183 +A+A ++ G + +S A A+ G +KA+L + VR Sbjct: 121 LARALSGRVSRGGVVAFMSSQMASLALGLSATMPLYGASKAALNSLVRSWEGEFEELPFS 180 Query: 184 VNAISAGPIRTLA 196 + + G +RT Sbjct: 181 LLLLHPGWVRTEM 193 >5LCX-A nrPDB Length = 316 Score = 77.6 bits (190), Expect = 6e-15, Method: Composition-based stats. Identities = 24/123 (19%), Positives = 49/123 (39%), Gaps = 8/123 (6%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKL-----KGRVEEFAAQLGSDIVL 61 + LVTG I + I + + +G + T +N+K + ++E + Sbjct: 8 RYALVTGA--NKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKELNVSENRLVFH 65 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQL-DGDYVNAVTREGFKIAHDIS 120 Q DV + AS+ + + + K D V++ G + + + D N FK + Sbjct: 66 QLDVTDLASVAAVAVFIKSKFGKLDILVNNAGVSGVEMVGDVSVFNEYIEADFKALQALE 125 Query: 121 SYS 123 + + Sbjct: 126 AGA 128 Score = 39.4 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 32/84 (38%), Gaps = 6/84 (7%) Query: 154 PNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAV 213 P++ ++KA+L A + A R+NAI G +T A A Sbjct: 235 PHFAAERVSKAALNAYTKIAAKKYPSF--RINAICPGYAKTDITFHAGPLSVAEA---AQ 289 Query: 214 TPIRRTVTIEDVGNSAAFLCSDLS 237 P++ + D G S F D + Sbjct: 290 VPVKLALLP-DGGPSGCFFPRDKA 312 >3U9L-A nrPDB Length = 324 Score = 76.4 bits (187), Expect = 1e-14, Method: Composition-based stats. Identities = 48/219 (21%), Positives = 78/219 (35%), Gaps = 20/219 (9%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELA-----FTYQNDKLKGRVEEFAAQLGSDI-V 60 K IL+TG +S A+A+ G + +N + FA D+ Sbjct: 6 KIILITGASS--GFGRLTAEALAGAGHRVYASMRDIVGRNASNVEAIAGFARDNDVDLRT 63 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 L+ DV S+D ++ + D +H+ G + A T E F +DI+ Sbjct: 64 LELDVQSQVSVDRAIDQIIGEDGRIDVLIHNAG-----HMVFGPAEAFTPEQFAELYDIN 118 Query: 121 SYSFVAMAKACRSML---NPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAM 177 S + +A + G + S A P AKA+++A A + Sbjct: 119 VLSTQRVNRAALPHMRRQKHGLLIWISSSSSAGGTPPYLAPYFAAKAAMDAIAVQYAREL 178 Query: 178 GPEGVRVNAISAGPIRT----LAASGIKDFRKMLAHCEA 212 G+ + I G + A SG+ D A EA Sbjct: 179 SRWGIETSIIVPGAFTSGTNHFAHSGVPDDHARQAEYEA 217 >1B15-A nrPDB Length = 254 Score = 75.3 bits (184), Expect = 3e-14, Method: Composition-based stats. Identities = 34/219 (15%), Positives = 69/219 (31%), Gaps = 18/219 (8%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAE-LAFTYQNDKLKGRVEEFAAQLGSDIVLQ 62 L+ K ++ VA+ I ++ + + + + + E A +I Sbjct: 3 LTNKNVIF--VAALGGIGLDTSRELVKRNLKNFVILDRVENPTALAELKAINPKVNITFH 60 Query: 63 C-DVAED-ASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS 120 DV A + ++ D ++ G LD + F + + Sbjct: 61 TYDVTVPVAESKKLLKKIFDQLKTVDILINGAGI-----LDDHQIERTIAINFTGLVNTT 115 Query: 121 SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP- 179 + + + PG + + + AI V +KA++ + +A + P Sbjct: 116 T---AILDFWDKRKGGPGGIIANICSVTGFNAIHQVPVYSASKAAVVSFTNSLAK-LAPI 171 Query: 180 EGVRVNAISAGPIRTLAASGIK---DFRKMLAHCEAVTP 215 GV +I+ G RT D +A P Sbjct: 172 TGVTAYSINPGITRTPLVHTFNSWLDVEPRVAELLLSHP 210 >1MG5-A nrPDB Length = 255 Score = 73.3 bits (179), Expect = 9e-14, Method: Composition-based stats. Identities = 32/215 (14%), Positives = 61/215 (28%), Gaps = 17/215 (7%) Query: 4 LSGK-RILVTGVASKLSIAYGIAQAM-HREGAELAFTYQNDKLKGRVEEFAAQLGSDIVL 61 L+ K I V G+ I ++ + R+ L + + E A + Sbjct: 4 LTNKNVIFVAGLG---GIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKVTVTF 60 Query: 62 -QCDVAED-ASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDI 119 DV A + + D ++ G LD + + + Sbjct: 61 YPYDVTVPIAETTKLLKTIFAQLKTVDVLINGAGI-----LDDHQIERTIAVNYTGLVNT 115 Query: 120 SSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 ++ K PG + + + AI V KA++ +A + P Sbjct: 116 TTAILDFWDKRKG---GPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAK-LAP 171 Query: 180 -EGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAV 213 GV ++ G RT + + Sbjct: 172 ITGVTAYTVNPGITRTTLVHKFNSWLDVEPQVAEK 206 >4Z3K-A nrPDB Length = 275 Score = 71.8 bits (175), Expect = 3e-13, Method: Composition-based stats. Identities = 36/225 (16%), Positives = 78/225 (34%), Gaps = 24/225 (10%) Query: 8 RILVTGVASKLSIAYGIAQAMHRE-GAELAFTYQNDKLKGRVEEF--AAQLGSDIV-LQC 63 L+TG + A G+ L + +ND+ ++E A + G +V + Sbjct: 23 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 82 Query: 64 DVAEDASIDTMFAELGKV-----WPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHD 118 D+ +A + + L ++ + +++ G + +V+ Sbjct: 83 DLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAG--SLGDVSKGFVDLSDSTQVNNYWA 139 Query: 119 ISSYSFVAMAKACRSMLNP----GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMA 174 ++ S + + + ++ +S L A + + + KA+ + + +A Sbjct: 140 LNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA 199 Query: 175 NAMGPEGVRVNAISAGPIRTLA------ASGIKDFRKMLAHCEAV 213 VRV + GP+ T S D RK L +A Sbjct: 200 LE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAK 242 >4HWK-A nrPDB Length = 288 Score = 71.8 bits (175), Expect = 3e-13, Method: Composition-based stats. Identities = 36/225 (16%), Positives = 78/225 (34%), Gaps = 24/225 (10%) Query: 8 RILVTGVASKLSIAYGIAQAMHRE-GAELAFTYQNDKLKGRVEEF--AAQLGSDIV-LQC 63 L+TG + A G+ L + +ND+ ++E A + G +V + Sbjct: 36 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 95 Query: 64 DVAEDASIDTMFAELGKV-----WPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHD 118 D+ +A + + L ++ + +++ G + +V+ Sbjct: 96 DLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAG--SLGDVSKGFVDLSDSTQVNNYWA 152 Query: 119 ISSYSFVAMAKACRSMLNP----GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMA 174 ++ S + + + ++ +S L A + + + KA+ + + +A Sbjct: 153 LNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA 212 Query: 175 NAMGPEGVRVNAISAGPIRTLA------ASGIKDFRKMLAHCEAV 213 VRV + GP+ T S D RK L +A Sbjct: 213 LE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAK 255 >1OAA-A nrPDB Length = 259 Score = 66.4 bits (161), Expect = 1e-11, Method: Composition-based stats. Identities = 27/237 (11%), Positives = 83/237 (35%), Gaps = 22/237 (9%) Query: 8 RILVTGVASKLSIAYGIAQAMHRE---GAELAFTYQNDKLKGRVEEFAAQLGSDIVL--- 61 ++TG + +A + R G+ + + +++ + +++E D+ + Sbjct: 8 VCVLTGAS--RGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLA 65 Query: 62 QCDVAEDASIDTMFAELGKV-----WPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIA 116 D+ +A + + + + ++ + +++ + ++N Sbjct: 66 AADLGTEAGVQRLLSAVRELPRPEGLQRL-LLINNAATLGD--VSKGFLNVNDLAEVNNY 122 Query: 117 HDISSYSFVAMAKACRSMLNPG----SALLTLSYLGAERAIPNYNVMGLAKASLEANVRY 172 ++ S + + + ++ +S L A + + + KA+ + + Sbjct: 123 WALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQV 182 Query: 173 MANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSA 229 +A VRV + + GP+ ++ K + ++ + D G SA Sbjct: 183 LAAE--EPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLKSDGALVDCGTSA 237 >5TQV-A nrPDB Length = 233 Score = 58.3 bits (140), Expect = 3e-09, Method: Composition-based stats. Identities = 29/217 (13%), Positives = 67/217 (30%), Gaps = 24/217 (11%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVA 66 K +L+ G + + + R+G + T ++D + A D+ Sbjct: 10 KTVLIVGAS--RGLGREFVRQYQRDGWNVIATARDDASLAALRALGAH-----AHALDIT 62 Query: 67 EDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVA 126 + I + +L + D V G + V + + F + + Sbjct: 63 QPEQIAALGWKLDGE--RLDVAVVVSGVYGP---RTEGVETIASDDFDTVMHTNVRGPMQ 117 Query: 127 MAKACRSMLNPGSALLT-----LSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEG 181 + ++ +L + + + + +KA+L +R + Sbjct: 118 LLPILLPLVEDARGVLAVVSSRMGSISEATGTTGW-LYRASKAALNDVLRIASLQ--TRH 174 Query: 182 VRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRR 218 ++ G +RT + L +VT +RR Sbjct: 175 AACISLHPGWVRTDMGGA----QAALDPATSVTGMRR 207 >3SLK-A nrPDB Length = 795 Score = 56.8 bits (136), Expect = 1e-08, Method: Composition-based stats. Identities = 39/191 (20%), Positives = 64/191 (33%), Gaps = 29/191 (15%) Query: 8 RILVTGVASKLSIAYGIAQAMH-REGA-ELAFTYQNDKLKGRVEEFAAQL---GSDIVLQ 62 +LVTG L +A+ + G L + E AQL G+++ LQ Sbjct: 532 TVLVTGGTGALG--AEVARHLVIERGVRNLVLVSRRGPAASGAAELVAQLTAYGAEVSLQ 589 Query: 63 -CDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 CDVA+ ++ + A + P VH+ G LD ++T E Sbjct: 590 ACDVADRETLAKVLASIPDEHP-LTAVVHAAGV-----LDDGVSESLTVERLDQVLRPKV 643 Query: 122 YSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEAN----------VR 171 A+ +++P AL+ S + A + L+A R Sbjct: 644 DG----ARNLLELIDPDVALVLFSSVSGVLGSGGQGNYAAANSFLDALAQQRQSRGLPTR 699 Query: 172 YMANA-MGPEG 181 +A G Sbjct: 700 SLAWGPWAEHG 710 >3ORF-A nrPDB Length = 251 Score = 48.3 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 37/194 (19%), Positives = 62/194 (31%), Gaps = 19/194 (9%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVA 66 K ILV G + GAE+ +++ +F +D + Sbjct: 23 KNILVLGGSG-------------ALGAEVVKFFKSKSWNTISIDFRENPNADHSFTIKDS 69 Query: 67 EDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVA 126 + I ++ ++ K D FV + G G D + K D++ YS A Sbjct: 70 GEEEIKSVIEKINSKSIKVDTFVCAAGGWSGGNASSDEF----LKSVKGMIDMNLYSAFA 125 Query: 127 MAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMG--PEGVRV 184 A +LN G + A G KA+ ++ +A+ G P G Sbjct: 126 SAHIGAKLLNQGGLFVLTGASAALNRTSGMIAYGATKAATHHIIKDLASENGGLPAGSTS 185 Query: 185 NAISAGPIRTLAAS 198 I + T Sbjct: 186 LGILPVTLDTPTNR 199 >2PK3-A nrPDB Length = 321 Score = 47.9 bits (113), Expect = 4e-06, Method: Composition-based stats. Identities = 50/272 (18%), Positives = 94/272 (34%), Gaps = 61/272 (22%) Query: 8 RILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAE 67 R L+TGVA + +A + + E+ T +N++ K L + ++ D+ + Sbjct: 14 RALITGVAGFVG--KYLANHLTEQNVEVFGTSRNNEAK---------LPNVEMISLDIMD 62 Query: 68 DASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAM 127 + + +++ K D H A + ++N K + + + + Sbjct: 63 SQRVKKVISDI-----KPDYIFH---LAAKSSVKDSWLNK------KGTFSTNVFGTLHV 108 Query: 128 AKACRSMLNPGSALLTLSY-------------LGAERAIPNYNVMGLAKASLEANVRYMA 174 A R N +LT+ + E + + G++KAS+ R Sbjct: 109 LDAVRD-SNLDCRILTIGSSEEYGMILPEESPVSEENQLRPMSPYGVSKASVGMLARQYV 167 Query: 175 NAMGPEGV---RVNAISA----GPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIE---- 223 A G + + N I G + A I D E PI + +E Sbjct: 168 KAYGMDIIHTRTFNHIGPGQSLGFVTQDFAKQIVDIE-----MEKQEPIIKVGNLEAVRD 222 Query: 224 --DVGNSAA--FLCSDLSAGISGEVVHVDGGF 251 DV + +L S +G+V +V G Sbjct: 223 FTDVRDIVQAYWLLSQYGK--TGDVYNVCSGI 252 >4LIS-A nrPDB Length = 371 Score = 46.8 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 28/178 (15%), Positives = 52/178 (29%), Gaps = 36/178 (20%) Query: 8 RILVTGVASKLSIAYGIAQAMHREGAELAFTYQ--NDKLKGRVEEFAAQLGSDIVLQCDV 65 +LVTG I A+ G ++ N + Q DV Sbjct: 5 SVLVTGGTGY--IGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELISGKKAEFAQLDV 62 Query: 66 AEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFV 125 ++A+ D +F + P D +H + ++ + ++ Y + Sbjct: 63 TDEAAFDKVF----EAHPDIDSVIHFAALKAVGESGEKPLDY---------YHVNVYGTI 109 Query: 126 AMAKACRSMLNPGSALLTLSYLGAERA----------IPNY------NVMGLAKASLE 167 + RSM+ + S IP + N G K ++E Sbjct: 110 CL---LRSMVRHNVTNIVFSSSATVYGDATRFPDMIPIPEHCPLGPTNPYGNTKFAIE 164 >3RFT-A nrPDB Length = 267 Score = 46.0 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 29/169 (17%), Positives = 56/169 (33%), Gaps = 44/169 (26%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVA 66 KR+LVTG A +L + + + AE+ + ++ +QCD+A Sbjct: 4 KRLLVTGAAGQLG--RVMRERLAPM-AEIL-------RLADLSPLDPAGPNEECVQCDLA 53 Query: 67 EDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVA 126 + +++ M A DG VH G + + F+ + Sbjct: 54 DANAVNAMVA-------GCDGIVHLGGIS-------------VEKPFEQILQGNIIGLYN 93 Query: 127 MAKACRSMLNPGSALLTLSYLGAERAIPNY------------NVMGLAK 163 + +A R+ P ++ S P + G++K Sbjct: 94 LYEAARAHGQP--RIVFASSNHTIGYYPQTERLGPDVPARPDGLYGVSK 140 >2Q1W-A nrPDB Length = 333 Score = 44.5 bits (104), Expect = 5e-05, Method: Composition-based stats. Identities = 32/191 (16%), Positives = 65/191 (34%), Gaps = 32/191 (16%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVA 66 K++ +TG+ + I IA+ + G ++ D E + ++ +A Sbjct: 22 KKVFITGICGQ--IGSHIAELLLERGDKVVGI---DNFATGRREHLKDHPNLTFVEGSIA 76 Query: 67 EDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVT------REGFKIAHDIS 120 + A ++ + +L + D VH+ D+ N + A + Sbjct: 77 DHALVNQLIGDL-----QPDAVVHTAASYKDP---DDWYNDTLTNCVGGSNVVQAAKKNN 128 Query: 121 SYSFV----AMAKACRSM-----LNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVR 171 FV A+ + + L+ SY ++ A +Y L+ Sbjct: 129 VGRFVYFQTALCYGVKPIQQPVRLDHPRNPANSSYAISKSANEDYLEYS----GLDFVTF 184 Query: 172 YMANAMGPEGV 182 +AN +GP V Sbjct: 185 RLANVVGPRNV 195 >2GN9-A nrPDB Length = 344 Score = 42.1 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 24/162 (14%), Positives = 49/162 (30%), Gaps = 22/162 (13%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVL 61 L + IL+TG + + + + A+ Y D+LK Sbjct: 17 NMLDNQTILITGGTGSFGKCF-VRKVLDTTNAKKIIVYSRDELKQSEMAMEFNDPRMRFF 75 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 DV + ++ D +H+ + + + + ++ I++ Sbjct: 76 IGDVRDLERLNYALE-------GVDICIHAAALKHVPIAEYNPLECIKTNIMGASNVINA 128 Query: 122 YSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAK 163 + N S ++ LS A I N+ G K Sbjct: 129 C-----------LKNAISQVIALSTDKAANPI---NLYGATK 156 >6ACF-A nrPDB Length = 367 Score = 41.4 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 16/90 (17%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN-DKLKGRVEEFAAQ---LGSDI 59 L GK + V GV + +AY + + +H EGA+L T N + + VEEF A+ Sbjct: 171 LEGKVVAVQGVGN---VAYHLCRHLHEEGAKLIVTDINKEAVARAVEEFGAKAVDPNDIY 227 Query: 60 VLQCD---------VAEDASIDTMFAELGK 80 ++CD + D +I + A++ Sbjct: 228 GVECDIFAPCALGGIINDQTIPQLKAKVIA 257 >6BWL-A nrPDB Length = 328 Score = 40.6 bits (94), Expect = 6e-04, Method: Composition-based stats. Identities = 25/164 (15%), Positives = 53/164 (32%), Gaps = 8/164 (4%) Query: 8 RILVTGVASKLSIAYGIAQAMHREGAELAFTYQ-NDKLKGRVEEFAAQLGSDIVLQCDVA 66 +ILVTG A I + + + ++ E+ + + EFA L +Q D+ Sbjct: 2 KILVTGGAGF--IGRWVVKRLLQDKHEVWILDNLANSTTANITEFAHDLNLKQCIQGDIK 59 Query: 67 EDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVA 126 + + +F + SI T F + +Y Sbjct: 60 DKKLVAQLFEN--NSFDLCYHLAASINVQDSIDDARATFENDTIGTFNLLEQCLNYDVKM 117 Query: 127 MAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANV 170 + + + + + + +S L + + +K + E V Sbjct: 118 VFMSTCMVYDKATNIQGISELDPIKPA---SPYAGSKIAAENMV 158 >5INT-A nrPDB Length = 220 Score = 40.2 bits (93), Expect = 9e-04, Method: Composition-based stats. Identities = 19/111 (17%), Positives = 32/111 (28%), Gaps = 31/111 (27%) Query: 2 GFLSGKRILVTGVASKLSI--------------AYGIAQAMHREGAELAFTYQNDKLKGR 47 L GKRIL+T ++ I Y IA+ GAE+ Sbjct: 2 NALQGKRILITAGPTREKIDPVRFMTNFSSGKMGYAIAEVAVNLGAEVILV--------- 52 Query: 48 VEEFAAQLGSDIVLQCDVA--EDASIDTMFAELGKVWPKFDGFVHSIGFAP 96 + + V + S M + + + D + + A Sbjct: 53 ------SGPTALNPPLHVTTVQVESAQDMLEAVIQHYQNVDVVIKTAAVAD 97 >1DIR-A nrPDB Length = 241 Score = 40.2 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 29/170 (17%), Positives = 51/170 (30%), Gaps = 17/170 (10%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVA 66 +R+LV G + ++ QA +A + + S Sbjct: 8 RRVLVYGG--RGALGSRCVQAFRARNWWVASIDVVENEEASASVIVKMTDSF-------- 57 Query: 67 EDASIDTMFAELGKVWP--KFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSF 124 D + AE+GK+ K D + G G + +K + S+ S Sbjct: 58 -TEQADQVTAEVGKLLGDQKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSIWTSTIS- 115 Query: 125 VAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMA 174 + L G L A P G+AK ++ + +A Sbjct: 116 ---SHLATKHLKEGGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLA 162 >1OOE-A nrPDB Length = 236 Score = 39.4 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 36/199 (18%), Positives = 64/199 (32%), Gaps = 22/199 (11%) Query: 5 SGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCD 64 SGK I+ K ++ I + + G + + + S+I++ + Sbjct: 3 SGKVIV---YGGKGALGSAILEFFKKNGYTVLNIDLSANDQA---------DSNILVDGN 50 Query: 65 VAEDASIDTMFAELGKVWPK--FDGFVHSIG-FAPGDQLDGDYVNAVTREGFKIAHDISS 121 ++ + DG G +A G D+V + + S Sbjct: 51 KNWTEQEQSILEQTASSLQGSQVDGVFCVAGGWAGGSASSKDFV-----KNADLMIKQSV 105 Query: 122 YSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYM-ANAMG-P 179 +S AK + L PG L A P+ G+AKA++ + A G P Sbjct: 106 WSSAIAAKLATTHLKPGGLLQLTGAAAAMGPTPSMIGYGMAKAAVHHLTSSLAAKDSGLP 165 Query: 180 EGVRVNAISAGPIRTLAAS 198 + V I + T Sbjct: 166 DNSAVLTIMPVTLDTPMNR 184 >3ENK-A nrPDB Length = 341 Score = 38.3 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 26/72 (36%), Gaps = 4/72 (5%) Query: 8 RILVTGVASKLSIAYGIAQAMHREGAELAFTY--QNDKLKGRVEEFAAQLGSDIVLQCDV 65 ILVTG A I A + G ++ N K + + + DV Sbjct: 7 TILVTGGAGY--IGSHTAVELLAHGYDVVIADNLVNSKREAIARIEKITGKTPAFHETDV 64 Query: 66 AEDASIDTMFAE 77 +++ ++ +F Sbjct: 65 SDERALARIFDA 76 >3VPX-A nrPDB Length = 364 Score = 36.7 bits (84), Expect = 0.009, Method: Composition-based stats. Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 3/45 (6%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRV 48 L+GK + V GV + +AY + + +H EGA+L T N++ R Sbjct: 171 LAGKTVAVQGVGN---VAYALCEYLHEEGAKLIITDINEEAVQRA 212 >3SC6-A nrPDB Length = 287 Score = 36.4 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 22/153 (14%), Positives = 52/153 (33%), Gaps = 28/153 (18%) Query: 34 ELAFTYQNDKLKGRVEEFAAQLGSDIV----LQCDVAEDASIDTMFAELGKVWPKFDGFV 89 + T N +L +++E DI D+ + + + E+ + + Sbjct: 7 RVIITGANGQLGKQLQEELNPEEYDIYPFDKKLLDITNISQVQQVVQEI-----RPHIII 61 Query: 90 HSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGA 149 H + DQ + + +A+ I++ +A A ++ ++ Y+ Sbjct: 62 HCAAYTKVDQAEKER---------DLAYVINAIGARNVAVAS-QLVGAKLVYISTDYVFQ 111 Query: 150 ERAIPNY---------NVMGLAKASLEANVRYM 173 Y N+ G +K + E V+ + Sbjct: 112 GDRPEGYDEFHNPAPINIYGASKYAGEQFVKEL 144 >4K28-A nrPDB Length = 269 Score = 36.0 bits (82), Expect = 0.015, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 24/71 (33%), Gaps = 4/71 (5%) Query: 5 SGKRILVTGVASKLSIAYGIAQAMHREG-AELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 +GKR LV G + IA A+ G A + + G V E + + Sbjct: 124 AGKRALVIGCG---GVGSAIAYALAEAGIASITLCDPSTARMGAVCELLGNGFPGLTVST 180 Query: 64 DVAEDASIDTM 74 + D + Sbjct: 181 QFSGLEDFDLV 191 >3NJ4-A nrPDB Length = 435 Score = 35.6 bits (81), Expect = 0.024, Method: Composition-based stats. Identities = 31/153 (20%), Positives = 59/153 (38%), Gaps = 13/153 (8%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN--DKLKGRVEEFAAQLGSDIV 60 ++GK +V G + G AQA+ GA + T + + L+ +E + + Sbjct: 213 MIAGKVAVVAGYGD---VGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEAC 269 Query: 61 LQCD--VAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHD 118 + + V ID + + K D V +IG ++D ++N E I Sbjct: 270 QEGNIFVTTTGCIDIILGRHFEQM-KDDAIVCNIGHFDV-EIDVKWLNENAVEKVNIKPQ 327 Query: 119 ISSYSFVAMAK----ACRSMLNPGSALLTLSYL 147 + Y + A ++N G A+ S++ Sbjct: 328 VDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFV 360 >3SXP-A nrPDB Length = 362 Score = 35.2 bits (80), Expect = 0.029, Method: Composition-based stats. Identities = 27/172 (15%), Positives = 51/172 (29%), Gaps = 26/172 (15%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHRE--GAELAF-------TYQNDKLKGRVEEFAAQ 54 L + IL+TG A + +A A++ T ++ + F Sbjct: 8 LENQTILITGGAGFVG--SNLAFHFQENHPKAKVVVLDKFRSNTLFSNNRPSSLGHFKNL 65 Query: 55 LG-SDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGF 113 +G V+ D+ + + FD H + L+ + V + F Sbjct: 66 IGFKGEVIAADINNPLDLRRLEKL------HFDYLFHQAAVSDTTMLNQELVMKTNYQAF 119 Query: 114 KIAHDISSYSFVAMAKACRSMLNPGSALLT--LSYLGAERAIPNYNVMGLAK 163 +I+ KA + + + P NV G +K Sbjct: 120 LNLLEIARS-----KKAKVIYASSAGVYGNTKAPNVVGKNESPE-NVYGFSK 165 >1Z45-A nrPDB Length = 699 Score = 35.2 bits (80), Expect = 0.032, Method: Composition-based stats. Identities = 27/171 (15%), Positives = 51/171 (29%), Gaps = 21/171 (12%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAE--LAFTYQNDKLKGRVEEFAAQLGSDIVLQCD 64 K +LVTG A I + G + +A N + D Sbjct: 12 KIVLVTGGAGY--IGSHTVVELIENGYDCVVADNLSNSTYDSVARLEVLTKHHIPFYEVD 69 Query: 65 VAEDASIDTMFAELGKVWPKFDGFVHSIGF--------APGDQLDGDYVNAVTREGFKIA 116 + + ++ +F E K D +H G P + + V Sbjct: 70 LCDRKGLEKVFKEY-----KIDSVIHFAGLKAVGESTQIPLRYYHNNILGTVVLLELMQQ 124 Query: 117 HDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLE 167 +++S + F + A + + + E + N G K ++E Sbjct: 125 YNVSKFVFSSSATVYG----DATRFPNMIPIPEECPLGPTNPYGHTKYAIE 171 >2Z95-A nrPDB Length = 345 Score = 34.4 bits (78), Expect = 0.054, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 36/77 (46%), Gaps = 5/77 (6%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQ--NDKLKGRVEEFAAQLGSDIVL 61 +SGKR L+TG+ + +A+ + +G E+ + + R++E + I + Sbjct: 1 MSGKRALITGIRGQDG--AYLAKLLLEKGYEVYGADRRSGEFASWRLKELGIENDVKI-I 57 Query: 62 QCDVAEDASIDTMFAEL 78 D+ E ++I ++ Sbjct: 58 HMDLLEFSNIIRTIEKV 74 >3OND-A nrPDB Length = 488 Score = 34.1 bits (77), Expect = 0.057, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 28/65 (43%), Gaps = 5/65 (7%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQND--KLKGRVEEFAAQLGSDIV 60 ++GK +V G + G A A+ + GA + T + L+ +E D+V Sbjct: 262 MIAGKVAVVAGYGD---VGKGCAAALKQAGARVIVTEIDPICALQATMEGLQVLTLEDVV 318 Query: 61 LQCDV 65 + D+ Sbjct: 319 SEADI 323 >2YNM-D nrPDB Length = 530 Score = 34.1 bits (77), Expect = 0.068, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 36/80 (45%), Gaps = 4/80 (5%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELA-FTYQNDKLKGRVEEFAAQLGSDIV 60 +L+GKR+ + G + + A IA G E+ + ++ +V A +LG + + Sbjct: 292 NYLTGKRVFIFGDGTHVLAAARIANE--ELGFEVVGIGTYSREMARKVRAAATELGLEAL 349 Query: 61 LQCD-VAEDASIDTMFAELG 79 + D + + SI EL Sbjct: 350 ITNDYLEVEESIKECAPELV 369 >4EUF-A nrPDB Length = 418 Score = 34.1 bits (77), Expect = 0.073, Method: Composition-based stats. Identities = 21/100 (21%), Positives = 40/100 (40%), Gaps = 13/100 (13%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAE-LAFTYQNDKLKGRV-----------EEFAAQ 54 K++L+ G +S +A I+ A A + +Y+ R+ +EFA + Sbjct: 61 KKVLIVGASSGFGLATRISVAFGGPEAHTIGVSYETGATDRRIGTAGWYNNIFFKEFAKK 120 Query: 55 LG-SDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIG 93 G D + + D + + + K D FV+S+ Sbjct: 121 KGLVAKNFIEDAFSNETKDKVIKYIKDEFGKIDLFVYSLA 160 >3DFZ-A nrPDB Length = 223 Score = 33.7 bits (76), Expect = 0.078, Method: Composition-based stats. Identities = 22/98 (22%), Positives = 37/98 (37%), Gaps = 14/98 (14%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDI---- 59 L G+ +LV G + IA + +EGA A T + + E+ A+ + Sbjct: 29 LKGRSVLVVGGGT---IATRRIKGFLQEGA--AITVVAPTVSAEINEWEAKGQLRVKRKK 83 Query: 60 VLQCDVAE-----DASIDTMFAELGKVWPKFDGFVHSI 92 V + D+ A+ D + K K D V+ Sbjct: 84 VGEEDLLNVFFIVVATNDQAVNKFVKQHIKNDQLVNMA 121 >3X2F-A nrPDB Length = 411 Score = 33.7 bits (76), Expect = 0.086, Method: Composition-based stats. Identities = 23/125 (18%), Positives = 45/125 (36%), Gaps = 7/125 (5%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFT--YQNDKLKGRVEEFAAQLGSDIV 60 ++GK ++V G GIA GA + T ++ ++ F + V Sbjct: 194 LVAGKNVVVAGYGWC---GRGIALRAAGLGARVIVTEVDPVKAVEAIMDGFTVMPMKEAV 250 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFV-HSIGFAPGDQLDGDYVNAVTREGFKIAHDI 119 D AS +T + DG V + G ++ + + E F+ ++ Sbjct: 251 KIADFVITASGNTDVLSKEDILSLKDGAVLANAGHFNV-EIPVRVLEEIAVEKFEARPNV 309 Query: 120 SSYSF 124 + Y+ Sbjct: 310 TGYTL 314 >1RPN-A nrPDB Length = 335 Score = 33.3 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 12/74 (16%), Positives = 29/74 (39%), Gaps = 5/74 (6%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAEL--AFTYQNDKLKGRVEEFAAQLGSDIVLQCD 64 + LVTG+ + +A+ + +G + ++ + R+ E + G D Sbjct: 15 RSALVTGITGQDG--AYLAKLLLEKGYRVHGLVARRSSDTRWRLRELGIE-GDIQYEDGD 71 Query: 65 VAEDASIDTMFAEL 78 +A+ S+ + Sbjct: 72 MADACSVQRAVIKA 85 >1GPJ-A nrPDB Length = 404 Score = 33.3 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 25/111 (22%), Positives = 38/111 (34%), Gaps = 19/111 (17%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV 60 +G L K +LV G + +A+++ G ++ R E A LG + V Sbjct: 162 LGSLHDKTVLVVGAGE---MGKTVAKSLVDRGVRAVL--VANRTYERAVELARDLGGEAV 216 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTRE 111 F EL + D V S AP + D V R+ Sbjct: 217 -------------RFDELVDHLARSDVVV-SATAAPHPVIHVDDVREALRK 253 >6ACQ-A nrPDB Length = 302 Score = 32.5 bits (73), Expect = 0.17, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 30/66 (45%), Gaps = 3/66 (4%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVA 66 K++ V G + + GIAQA +G E+ D+ R +F + S +V + + Sbjct: 22 KKVCVIGAGT---MGSGIAQAFAAKGFEVVLRDIKDEFVDRGLDFINKNLSKLVKKGKIE 78 Query: 67 EDASID 72 E ++ Sbjct: 79 EATKVE 84 >3H9U-A nrPDB Length = 436 Score = 32.5 bits (73), Expect = 0.17, Method: Composition-based stats. Identities = 33/152 (21%), Positives = 58/152 (38%), Gaps = 22/152 (14%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQ 62 ++GK V G + G A A+ GA + T ++ AA G ++L Sbjct: 208 MIAGKTACVCGYGD---VGKGCAAALRGFGARVVVT----EVDPINALQAAMEGYQVLLV 260 Query: 63 CDVAEDASI-------DTMFAELGKVWPKF--DGFVHSIGFAPGDQLDGDYVNAVTREGF 113 DV E+A I D + + +P+ D V +IG ++ ++ A +E Sbjct: 261 EDVVEEAHIFVTTTGNDDIITS--EHFPRMRDDAIVCNIGHF-DTEIQVAWLKANAKERV 317 Query: 114 KIAHDISSYSFVAMAKACRSMLNPGSALLTLS 145 ++ + Y MA +L L+ L Sbjct: 318 EVKPQVDRY---TMANGRHIILLAEGRLVNLG 346 >4QQW-A nrPDB Length = 964 Score = 32.1 bits (72), Expect = 0.27, Method: Composition-based stats. Identities = 37/227 (16%), Positives = 64/227 (28%), Gaps = 32/227 (14%) Query: 20 IAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDV----AEDASIDTMF 75 I I +EGA Q+ + R A + L DV ++ A + + Sbjct: 651 ITATIVDLFGKEGA------QSGRRPTRGAVLVATQVVEQSLDLDVDLMISDLAPVSLLL 704 Query: 76 AELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAV---------TREGFKIAHDISSYSFVA 126 G+ W +G Q V R + S Y Sbjct: 705 QRAGRCWRH-----EHLGIINRPQWAKQPELVVLTPEQNGDADRAPWFPRSWTSVYPLAL 759 Query: 127 MAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNA 186 + + + A + + + Y+ LA+ LEA++ M + G+ NA Sbjct: 760 LQRTYTLLRRRNGAPVQIPEDVQQLVDDVYDDDSLAED-LEADMERMGEELAQRGLARNA 818 Query: 187 ISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLC 233 + P A + + + R S LC Sbjct: 819 VIPDP--DDAEDNLNGLTEFSFDVDEHVLATRFG-----AGSVRVLC 858 >3HFS-A nrPDB Length = 338 Score = 31.7 bits (71), Expect = 0.32, Method: Composition-based stats. Identities = 24/141 (17%), Positives = 48/141 (34%), Gaps = 21/141 (14%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFA--AQLGSDIVLQCD 64 K V G + A + + + ++G + T ++ + +V +LG + + D Sbjct: 10 KTACVVGGTGFV--ASLLVKLLLQKGYAVNTTVRDPDNQKKVSHLLELQELGDLKIFRAD 67 Query: 65 VAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSF 124 + ++ S + A D H P D N + + + Sbjct: 68 LTDELSFEAPIA-------GCDFVFHVA--TPVHFASEDPENDMIKPAIQ--------GV 110 Query: 125 VAMAKACRSMLNPGSALLTLS 145 V + KAC + +LT S Sbjct: 111 VNVMKACTRAKSVKRVILTSS 131 >6GAR-A nrPDB Length = 349 Score = 31.7 bits (71), Expect = 0.35, Method: Composition-based stats. Identities = 21/156 (13%), Positives = 52/156 (33%), Gaps = 16/156 (10%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQ 62 GK ++++G + A A + ++ TY+ ++L G + + S Sbjct: 150 RFKGKTVIISGGGNS---AVDWANELEPIAKKVYVTYRKEELSGHEAQVKQLMNSSAECF 206 Query: 63 CDVA-------EDASIDTMFAELGKVWPK-----FDGFVHSIGFAPG-DQLDGDYVNAVT 109 + + ++ + D + + G+ L+ ++ Sbjct: 207 FNTSITKLIAGDNHEAIEYVELTNHETGEVSHLPIDEVIINHGYERDITLLENSELDVAI 266 Query: 110 REGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLS 145 + + IA + +S S V A +L L ++ Sbjct: 267 IDNYYIAGNANSESSVDGLYAAGDILKHEGKLHLIA 302 >1LU9-A nrPDB Length = 287 Score = 31.4 bits (70), Expect = 0.37, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 28/81 (34%), Gaps = 2/81 (2%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVL 61 G + GK+ +V + + A + EGAE+ + + + V Sbjct: 115 GSVKGKKAVVLAGTGPVGMRS--AALLAGEGAEVVLCGRKLDKAQAAADSVNKRFKVNVT 172 Query: 62 QCDVAEDASIDTMFAELGKVW 82 + A+DAS V+ Sbjct: 173 AAETADDASRAEAVKGAHFVF 193 >3CT4-A nrPDB Length = 332 Score = 31.0 bits (69), Expect = 0.50, Method: Composition-based stats. Identities = 43/227 (18%), Positives = 67/227 (29%), Gaps = 42/227 (18%) Query: 5 SGKRILVTGVASKL--------SIAY-------GI-----------AQAMHREGAELAF- 37 SGK LV+G S I A EGA + Sbjct: 45 SGKVALVSGGGSGHEPAHAGFVGEGMLSAAVCGAIFTSPTPDQIYEAIKSADEGAGVLLI 104 Query: 38 --TYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSI-GF 94 Y D + + A++ V Q V +D +++ G+ VH I G Sbjct: 105 IKNYLGDVMNFEMAREMAEMEEIKVEQIIVDDDIAVENSLYTQGRRGVAGTVLVHKILGA 164 Query: 95 APGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSAL--LTLSYLGAERA 152 A + D + + K+ +I + A + PG L + Y + Sbjct: 165 AAHQEASLDEIKDL---ADKVVKNIKTIGLALSAATVPEVGKPGFVLDDNEIEYGVGIHS 221 Query: 153 IPNY------NVMGLAKASLEANVRYMANAMG-PEGVRVNAISAGPI 192 P Y LA + G G+ VN + A P+ Sbjct: 222 EPGYRREKMKTSYELATELVGKLKEEFKFEAGQKYGILVNGMGATPL 268 >1BXK-A nrPDB Length = 355 Score = 31.0 bits (69), Expect = 0.50, Method: Composition-based stats. Identities = 32/187 (17%), Positives = 62/187 (33%), Gaps = 34/187 (18%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFA--AQLGSDIVLQCD 64 ++IL+TG A I + + + E ++ G + A AQ + D Sbjct: 2 RKILITGGAGF--IGSALVRYIINETSDAVVVVDKLTYAGNLMSLAPVAQSERFAFEKVD 59 Query: 65 VAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQ-LDGDYVNAVTREGFKIAHDISSYS 123 + + A + +F E + D +H + D+ +DG F + + +Y+ Sbjct: 60 ICDRAELARVFTEH-----QPDCVMHLAAESHVDRSIDGPA-------AFIETNIVGTYT 107 Query: 124 FVAMAKACRSMLNP-----------------GSALLTLSYLGAERAIPNYNVMGLAKASL 166 + A+A + L G T + + +KAS Sbjct: 108 LLEAARAYWNALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPYSASKASS 167 Query: 167 EANVRYM 173 + VR Sbjct: 168 DHLVRAW 174 >2DFV-A nrPDB Length = 347 Score = 31.0 bits (69), Expect = 0.53, Method: Composition-based stats. Identities = 31/186 (16%), Positives = 62/186 (33%), Gaps = 30/186 (16%) Query: 2 GFLSGKRILVTGVA--SKLSIAYGIA---------------QAMHRE-GAELAFTYQNDK 43 G +SGK +L+TG L IA A + + ++ GA+ + Sbjct: 163 GPISGKSVLITGAGPLGLLGIAVAKASGAYPVIVSEPSDFRRELAKKVGADYVINPFEED 222 Query: 44 LKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGD 103 + V + G D+ L+ A +++ + + G PG + D Sbjct: 223 VVKEVMDITDGNGVDVFLEFSGA-PKALEQGLQAVTPA-GRVSLL----GLYPGK-VTID 275 Query: 104 YVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSA----LLTLSYLGAERAIPNYNVM 159 + N + + + I+ +L G ++T Y G ++ + +M Sbjct: 276 FNNLIIFKAL-TIYGITGRHLWETWYTVSRLLQSGKLNLDPIITHKYKGFDKYEEAFELM 334 Query: 160 GLAKAS 165 K Sbjct: 335 RAGKTG 340 >4DGK-A nrPDB Length = 501 Score = 31.0 bits (69), Expect = 0.57, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 26/72 (36%), Gaps = 3/72 (4%) Query: 11 VTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDAS 70 V G +A + G + Q DK GR + Q + + + ++ Sbjct: 6 VIGAGFG---GLALAIRLQAAGIPVLLLEQRDKPGGRAYVYEDQGFTFDAGPTVITDPSA 62 Query: 71 IDTMFAELGKVW 82 I+ +FA GK Sbjct: 63 IEELFALAGKQL 74 >2OWO-A nrPDB Length = 671 Score = 30.6 bits (68), Expect = 0.63, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 35/73 (47%), Gaps = 2/73 (2%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFT-YQNDKLKGRVEEFAAQLGSDIVLQ 62 +GK +++TG S++S A+ + GA++A + + L E ++L L Sbjct: 598 FAGKTVVLTGSLSQMSRDDAKAR-LVELGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELG 656 Query: 63 CDVAEDASIDTMF 75 +V ++A + + Sbjct: 657 IEVIDEAEMLRLL 669 >4PZE-A nrPDB Length = 284 Score = 30.6 bits (68), Expect = 0.75, Method: Composition-based stats. Identities = 27/194 (13%), Positives = 56/194 (28%), Gaps = 17/194 (8%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVA 66 + + + G + + GIAQA G + +D + A ++ + + Sbjct: 4 RTVGIVGAGT---MGNGIAQACAVVGLNVVMVDISDAAVQKGVATVASSLDRLIKKEKLT 60 Query: 67 EDASIDTMF----AELGKVWPKFDGFVHSIG-FAPGDQLDGDYVNAVTREGFKIAHDISS 121 E + + D + + ++ + E IA + SS Sbjct: 61 EADKASALARIKGSTSYDDLKATDIVIEAATENYDLKVKILKQIDGIVGENVIIASNTSS 120 Query: 122 YSFVAMAKACRSMLNPGSALLT--LSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGP 179 S +A + + I A++EA + +G Sbjct: 121 ISITKLAAVTSRADRFIGMHFFNPVPVMALVELIRGLQTSDTTHAAVEALSK----QLGK 176 Query: 180 EGVRV-NAISAGPI 192 + V N S G + Sbjct: 177 YPITVKN--SPGFV 188 >4W5U-B nrPDB Length = 408 Score = 30.2 bits (67), Expect = 0.94, Method: Composition-based stats. Identities = 25/157 (15%), Positives = 47/157 (29%), Gaps = 17/157 (10%) Query: 54 QLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDG-DYVNAVTREG 112 + + L CD + + + A L + D V + A G + + Sbjct: 183 EYPNACGLTCDSSGPDAFRNLMAALRSTFG--DELVTAAVTADGTPGGKIEATDYAGAAQ 240 Query: 113 FKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYN-----VMGLAKA-SL 166 + +++ +Y F A S L + IP + KA + Sbjct: 241 YVDWYNVMTYDFFGAWDAQGPTAPH-------SPLTSYDGIPKQGFTSADAIAAFKAQGV 293 Query: 167 EANVRYMANAMGPEGVR-VNAISAGPIRTLAASGIKD 202 A+ + G V + G T A+G + Sbjct: 294 PADKLLLGIGFYGRGWTGVTQDAPGGTATGPAAGTWE 330 >6BII-A nrPDB Length = 333 Score = 30.2 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 21/118 (17%), Positives = 37/118 (31%), Gaps = 13/118 (11%) Query: 6 GKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQND------KLKGRVEEFAAQLGSDI 59 GK I + G I IA+ G + +T ++ +L + L Sbjct: 150 GKTIGIVGFGR---IGQAIAKRAKGFGMRILYTARSRKPEAEKELGAEFKPLEELLRESD 206 Query: 60 VLQCDVAEDASIDTMF-AELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIA 116 + V M E ++ V+ A G +D + +EG+ A Sbjct: 207 FVVLAVPLTKETYHMINEERLRLMKPTAVLVN---VARGKVVDTKALIRALKEGWIAA 261 >1F14-A nrPDB Length = 310 Score = 30.2 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 27/73 (36%), Gaps = 5/73 (6%) Query: 11 VTGVASKLSIAYGIAQAMHREGAELAFTYQND----KLKGRVEEFAAQLGSDIVLQCDVA 66 VT + L + GIAQ G + Q + K K +EE ++ + A Sbjct: 18 VTVIGGGL-MGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENPKA 76 Query: 67 EDASIDTMFAELG 79 D ++ + + Sbjct: 77 GDECVEKTLSTIA 89 >5KIA-A nrPDB Length = 351 Score = 29.8 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 30/84 (35%), Gaps = 10/84 (11%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 L G+ +L+TG +A IA+ + + T ND A ++ Sbjct: 170 LVGEDVLITGAGPIGVMAVAIAKHVGAR--NVVITDINDYRLDLARRMGATRAVNV---- 223 Query: 64 DVAEDASIDTMFAELGKVWPKFDG 87 S+ + A+L + FD Sbjct: 224 ---SRESLRDVMADL-HMTEGFDV 243 >6G4S-u nrPDB Length = 804 Score = 29.8 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 7/46 (15%), Positives = 19/46 (41%), Gaps = 9/46 (19%) Query: 226 GNSAAFLCSDL---------SAGISGEVVHVDGGFSIAAMNELELK 262 ++ F+ S+ S + G+ ++V+ I + ++K Sbjct: 255 AHAVDFVPSEENNLVGTLKISGYVRGQTLNVNRLLHIVGYGDFQMK 300 >2EER-A nrPDB Length = 347 Score = 29.8 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 28/85 (32%), Gaps = 7/85 (8%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVA 66 K ++V G L I A GA + ++ E A + G+D V+ Sbjct: 172 KTLVVIGAGGGLG-TMAIQIAKAVSGATIIGVD----VREEALEAAKRAGADYVINASSQ 226 Query: 67 EDASIDTMFAELGKVWPKFDGFVHS 91 + S + D +++ Sbjct: 227 DPVSEIRRITQGKGADAVID--LNN 249 >4MIT-A nrPDB Length = 186 Score = 29.4 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 11/59 (18%), Positives = 25/59 (42%), Gaps = 7/59 (11%) Query: 23 GIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKV 81 I + + +G + T + ++LK R++ ++C ++ T+F E K Sbjct: 131 AIVKRLTEQGMTVINTAKGEELKNRIKAVK-------YIECSAKTSENLKTVFDEAVKT 182 >5OPT-L nrPDB Length = 273 Score = 29.4 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 33/87 (37%), Gaps = 12/87 (13%) Query: 6 GKRILVTGVASKLSIA-----------YGIAQAMHREGAELAFTYQND-KLKGRVEEFAA 53 GK ++VTG A++ I + IA+ G E A N + ++ Sbjct: 175 GKVVMVTGGANRGRIGEIMSIERHPGAFDIARLKDAAGHEFATRASNIFVIGKDMQSVPV 234 Query: 54 QLGSDIVLQCDVAEDASIDTMFAELGK 80 L L+ +V ++ + AE K Sbjct: 235 TLPKQQGLRINVIQEREEKLIAAEARK 261 >5K1S-A nrPDB Length = 362 Score = 29.4 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 28/76 (36%), Gaps = 18/76 (23%) Query: 5 SGKRILVTGVASKLSI----------AYGIA--------QAMHREGAELAFTYQNDKLKG 46 +G+ +L+TG + + + A IA QA+ GA+ + Sbjct: 183 AGETVLITGASGGVGLSSVQLARLDGARVIAVTSSEAKVQALKEAGADEVIVSRGLDFAS 242 Query: 47 RVEEFAAQLGSDIVLQ 62 V + G D+ ++ Sbjct: 243 DVRKRTQGAGVDVAVE 258 >1IM2-A nrPDB Length = 444 Score = 29.4 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 29/69 (42%), Gaps = 5/69 (7%) Query: 194 TLAASGIKDFRKMLAHCEAVTPIRRTVTI-EDVGNSAAFLCSDLSAGISGEVVHVDGGFS 252 T A I + + RR T+ E + + +F SD ++G+ V++D + Sbjct: 371 TDAVKKIAEAAFRVNEKTENIGARRLHTVMERLMDKISFSASD----MNGQTVNIDAAYV 426 Query: 253 IAAMNELEL 261 A+ E+ Sbjct: 427 ADALGEVVE 435 >6AZ1-E nrPDB Length = 273 Score = 29.4 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 32/88 (36%), Gaps = 12/88 (13%) Query: 5 SGKRILVTGVASKLSIA-----------YGIAQAMHREGAELAFTYQND-KLKGRVEEFA 52 GK ++VTG A++ I + IA GAE A N + + Sbjct: 174 QGKAVIVTGGANRGRIGEIVKVECHPGAFNIAHLKDASGAEFATRAANIFVIGKDLNHLQ 233 Query: 53 AQLGSDIVLQCDVAEDASIDTMFAELGK 80 + L+ +V ++ + AE K Sbjct: 234 VTVPKQQGLRMNVIQEREERLIAAEARK 261 >6DEB-A nrPDB Length = 285 Score = 29.4 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 7/38 (18%), Positives = 17/38 (44%), Gaps = 2/38 (5%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN 41 L GK ++ G ++ + +A + GA ++ + Sbjct: 158 LEGKDAVIIGASNIVG--RPMATMLLNAGATVSVCHIK 193 >1FGS-A nrPDB Length = 428 Score = 29.4 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 14/33 (42%) Query: 5 SGKRILVTGVASKLSIAYGIAQAMHREGAELAF 37 G+ I VTG K S A IA + G + Sbjct: 38 QGRYIHVTGTNGKGSAANAIAHVLEASGLTVGL 70 >2IY3-A nrPDB Length = 432 Score = 29.4 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 10/65 (15%), Positives = 23/65 (35%) Query: 35 LAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGF 94 +A Q + ++ ++G ++ D SI E ++ + V + G Sbjct: 132 VAADTQRPAAREQLRLLGEKVGVPVLEVMDGESPESIRRRVEEKARLEARDLILVDTAGR 191 Query: 95 APGDQ 99 D+ Sbjct: 192 LQIDE 196 >2GAG-A nrPDB Length = 965 Score = 29.4 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 14/32 (43%) Query: 30 REGAELAFTYQNDKLKGRVEEFAAQLGSDIVL 61 R GA +A ND V E AA G V+ Sbjct: 282 RAGARIAVATTNDSAYELVRELAATGGVVAVI 313 >4B3J-A nrPDB Length = 736 Score = 29.0 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 32/81 (39%), Gaps = 4/81 (4%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVA 66 KRI V G + GIA + G E+ + + + + ++ +L + + + Sbjct: 342 KRIGVLGAGM---MGAGIAYVSAKAGYEVVLKDVSLEAAAKGKGYSEKLEAKALERGRTT 398 Query: 67 EDASIDTMFAELGKVWPKFDG 87 ++ S D + A + D Sbjct: 399 QERS-DALLARITPTADAADF 418 >3C1M-A nrPDB Length = 473 Score = 29.0 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 25/150 (16%), Positives = 49/150 (32%), Gaps = 27/150 (18%) Query: 8 RILV----TGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQC 63 L+ G+ A I +A+ E + Q Sbjct: 318 VALINIFGAGMVGVSGTAARIFKALGEEEVNVILISQGSSETNISL-------------- 363 Query: 64 DVAEDASIDTMFAELGKVWPKF---DGFVHSIGFAPGDQLDGDY-VNAVTREGFKIAHDI 119 V + +D L + + F ++ +D D V +V G + A I Sbjct: 364 -VVSEEDVDKALKALKREFGDFGKKSFLNNN--LIRDVSVDKDVCVISVVGAGMRGAKGI 420 Query: 120 SSYSFVAMAK--ACRSMLNPGSALLTLSYL 147 + F A+++ A M+ GS+ + +S++ Sbjct: 421 AGKIFTAVSESGANIKMIAQGSSEVNISFV 450 >3AOE-A nrPDB Length = 424 Score = 29.0 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 10/58 (17%), Positives = 20/58 (34%), Gaps = 6/58 (10%) Query: 5 SGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQ 62 +G+ + +T A+ I + EGA +A + F + +Q Sbjct: 198 TGRGVFITAAAAAEKIG------LQVEGARVAIQGFGNVGNAAARAFHDHGARVVAVQ 249 >3K30-A nrPDB Length = 690 Score = 29.0 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 20/49 (40%), Gaps = 3/49 (6%) Query: 8 RILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLG 56 R+LV G A+A+ G ++ L GRV + +A G Sbjct: 393 RVLVVGAGPS---GLEAARALGVRGYDVVLAEAGRDLGGRVTQESALPG 438 >2FFH-A nrPDB Length = 425 Score = 29.0 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 10/65 (15%), Positives = 23/65 (35%) Query: 35 LAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGF 94 +A Q + ++ ++G ++ D SI E ++ + V + G Sbjct: 132 VAADTQRPAAREQLRLLGEKVGVPVLEVMDGESPESIRRRVEEKARLEARDLILVDTAGR 191 Query: 95 APGDQ 99 D+ Sbjct: 192 LQIDE 196 >1ZEJ-A nrPDB Length = 293 Score = 29.0 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 15/84 (17%), Positives = 29/84 (34%), Gaps = 8/84 (9%) Query: 8 RILVTGVA-SKLSIAYGIAQAMHREGAELAFTYQNDK-LKGRVEEFAAQLGSDIVLQCDV 65 ++ V G IA IA E+ ++K L+ E+ +L S I + Sbjct: 14 KVFVIGAGLMGRGIAIAIASK-----HEVVLQDVSEKALEAAREQIPEELLSKIEFTTTL 68 Query: 66 AEDASIDTMFAELGKVWP-KFDGF 88 + D + + + K + Sbjct: 69 EKVKDCDIVMEAVFEDLNTKVEVL 92 >5M65-A nrPDB Length = 479 Score = 29.0 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 36/94 (38%), Gaps = 6/94 (6%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQND--KLKGRVEEFAAQLGSDIV 60 LSGK +V G + G A ++ + G + + + L+ +E + D Sbjct: 257 MLSGKVAMVAGFGD---VGKGSAASLRQAGCRVMVSEVDPICALQAAMEGYEVVTMEDAA 313 Query: 61 LQCDVAEDASIDTMFAELGKVWPKFD-GFVHSIG 93 + D+ A+ + + + D V +IG Sbjct: 314 PRADIFVTATGNKDIITIEHMRAMKDRAIVCNIG 347 >3HDH-A nrPDB Length = 302 Score = 29.0 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 31/79 (39%), Gaps = 8/79 (10%) Query: 7 KRILV---TGVASKLSIAYGIAQAMHREGAELAFTYQND----KLKGRVEEFAAQLGSDI 59 K+ILV T + L + GIAQ G + Q + K K +EE ++ Sbjct: 11 KKILVKHVTVIGGGL-MGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKK 69 Query: 60 VLQCDVAEDASIDTMFAEL 78 + A D ++ + + Sbjct: 70 FAENPKAGDEFVEKTLSSI 88 >2GGS-A nrPDB Length = 273 Score = 29.0 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 26/164 (15%), Positives = 62/164 (37%), Gaps = 39/164 (23%) Query: 8 RILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAE 67 R L+TG + +L I + E E+ Y + +++G + D+ + Sbjct: 2 RTLITGASGQLGIELS---RLLSERHEVIKVYNSSEIQGG-------------YKLDLTD 45 Query: 68 DASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAM 127 + + K + D +++ D+ + + + A+ I++ + + Sbjct: 46 ---FPRLEDFIIKK--RPDVIINAAAMTDVDKCEIEK---------EKAYKINAEAVRHI 91 Query: 128 AKACRSMLNPGSALLTLSYL-GAERA------IPN-YNVMGLAK 163 +A +++ ++ Y+ E+ IPN N GL+K Sbjct: 92 VRA-GKVIDSYIVHISTDYVFDGEKGNYKEEDIPNPINYYGLSK 134 >4V62-AB nrPDB Length = 510 Score = 29.0 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 19/67 (28%), Positives = 26/67 (38%), Gaps = 8/67 (11%) Query: 165 SLEANVRYMANAMGPEGVRVNAISA-GPIRTLAASGIKDFRKMLAHCEAVTPIR-----R 218 L +V+ +A GP+G N + G + A+GI L H P R R Sbjct: 173 GLTGSVQPVAPEWGPDG--FNPYNPGGVVAHHIAAGIVGIIAGLFHILVRPPQRLYKALR 230 Query: 219 TVTIEDV 225 IE V Sbjct: 231 MGNIETV 237 >1IZL-B nrPDB Length = 472 Score = 29.0 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 19/67 (28%), Positives = 26/67 (38%), Gaps = 8/67 (11%) Query: 165 SLEANVRYMANAMGPEGVRVNAISA-GPIRTLAASGIKDFRKMLAHCEAVTPIR-----R 218 L +V+ +A GP+G N + G + A+GI L H P R R Sbjct: 173 GLTGSVQPVAPEWGPDG--FNPYNPGGVVAHHIAAGIVGIIAGLFHILVRPPQRLYKALR 230 Query: 219 TVTIEDV 225 IE V Sbjct: 231 MGNIETV 237 >1OFI-A nrPDB Length = 310 Score = 28.7 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 29/69 (42%), Gaps = 5/69 (7%) Query: 194 TLAASGIKDFRKMLAHCEAVTPIRRTVTI-EDVGNSAAFLCSDLSAGISGEVVHVDGGFS 252 T A I + + RR T+ E + + +F SD ++G+ V++D + Sbjct: 237 TDAVKKIAEAAFRVNEKTENIGARRLHTVMERLMDKISFSASD----MNGQTVNIDAAYV 292 Query: 253 IAAMNELEL 261 A+ E+ Sbjct: 293 ADALGEVVE 301 >4J2O-A nrPDB Length = 363 Score = 28.7 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 25/166 (15%), Positives = 47/166 (28%), Gaps = 23/166 (13%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVL 61 K +L+TG S + + + + D+ K Sbjct: 19 SMFKDKVLLITGGTG--SFGNAVLKRFLETDIKEIRIFSRDEKKQDDMRKKYHSAKLKFY 76 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISS 121 DV + + + D H+ + + AV + Sbjct: 77 IGDVRD-------YNSILNATRGVDYIYHAAALKQVPSCEFHPMEAV---------KTNV 120 Query: 122 YSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLE 167 + +A + N ++ LS A I N MG++KA +E Sbjct: 121 LGTENVLEAA--IQNHVKRVVCLSTDKAVYPI---NAMGISKAMME 161 >2HK7-A nrPDB Length = 269 Score = 28.7 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 12/75 (16%), Positives = 27/75 (36%), Gaps = 11/75 (14%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVA 66 K ILV G + + A+ +EGA++ ++ K + + A + ++ V Sbjct: 124 KSILVLGAG---GASRAVIYALVKEGAKVFLW---NRTKEKAIKLAQKFPLEV-----VN 172 Query: 67 EDASIDTMFAELGKV 81 + + Sbjct: 173 SPEEVIDKVQVIVNT 187 >3G1U-A nrPDB Length = 437 Score = 28.7 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 29/150 (19%), Positives = 53/150 (35%), Gaps = 26/150 (17%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQ 62 ++GK V G + G A A+ GA + T ++ A+ G + L Sbjct: 209 MIAGKTCCVCGYGD---VGKGCAAALRAFGARVVVT----EVDPINALQASMEGYQVALV 261 Query: 63 CDVAEDASI-------DTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKI 115 DV DA I D + + D V +IG ++ ++ A +E +I Sbjct: 262 EDVMADAHIFVTTTGNDDIITSDHFPHMRDDAIVCNIGHF-DTEIQVGWLEANAKEHVEI 320 Query: 116 AHDISSYSFVAMAKACRSMLNPGSALLTLS 145 + Y+ + G ++ L+ Sbjct: 321 KPQVDRYT-----------MENGRHIILLA 339 >4U83-A nrPDB Length = 382 Score = 28.7 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 35/180 (19%), Positives = 65/180 (36%), Gaps = 21/180 (11%) Query: 91 SIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLN---PGSALLTLSYL 147 S P D G V +V + + + D + F M + L G + + Sbjct: 187 SAFIVPTDT-PGYEVMSVEHKLGQHSSDTCALGFTNMRVPVENRLGAEGEGYKIALANLE 245 Query: 148 GAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRV-------NAISAGPIRTLAASGI 200 G I V G+A+A+ EA A E + A++ A+ I Sbjct: 246 GGRIGIAAQAV-GMARAAFEA-----ARDYARERITFGKPIIEHQAVA--FRLADMATRI 297 Query: 201 KDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNELE 260 + R+M+ H A+ + E + A + S+++ + + + GG+ A +E Sbjct: 298 ETARQMVLHAAALREAGKPCLTE--ASMAKLVASEMAEQVCSAAIQIHGGYGYLADYPVE 355 >5A2X-A nrPDB Length = 555 Score = 28.7 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 42/112 (37%), Gaps = 16/112 (14%) Query: 42 DKLKGRVEEFAAQ--LGSDIVLQCDVA------EDASIDTMFAELGKVWPKFDGFVHSIG 93 D+LK +E G D D++ ++D + + + + FD +S+ Sbjct: 381 DQLKELADEKDKHVIGGYDCSFVSDLSKIKPTKNTETLDELLCDFFQYFGNFDFRKNSLN 440 Query: 94 FAPGDQLDGDYVNAVTREG-FKIAHDISSYS-------FVAMAKACRSMLNP 137 G +++ + + F+ +IS FVAMA+ +L Sbjct: 441 LRKGKEVNKPESSPLYIWNPFEQDLNISKNVNQPQLEKFVAMARESAWILQK 492 >2AA4-A nrPDB Length = 289 Score = 28.7 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 11/70 (15%), Positives = 20/70 (28%) Query: 6 GKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDV 65 G+ V +AS IA + A+ FT + + + L D+ Sbjct: 169 GRTGCVEAIASGRGIAAAAQGELAGADAKTIFTRAGQGDEQAQQLIHRSARTLARLIADI 228 Query: 66 AEDASIDTMF 75 + Sbjct: 229 KATTDCQCVV 238 >1RJ9-B nrPDB Length = 300 Score = 28.7 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 10/65 (15%), Positives = 23/65 (35%) Query: 35 LAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGF 94 +A Q + ++ ++G ++ D SI E ++ + V + G Sbjct: 132 VAADTQRPAAREQLRLLGEKVGVPVLEVMDGESPESIRRRVEEKARLEARDLILVDTAGR 191 Query: 95 APGDQ 99 D+ Sbjct: 192 LQIDE 196 >4EJ6-A nrPDB Length = 370 Score = 28.7 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 17/94 (18%), Positives = 27/94 (28%), Gaps = 8/94 (8%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVL 61 G +G + + G I Q GA K R+ E + Sbjct: 179 GIKAGSTVAILGGGV---IGLLTVQLARLAGATTVILSTRQATKRRLAEEVGATATVDPS 235 Query: 62 QCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFA 95 DV ++ + +G V D + G A Sbjct: 236 AGDV-----VEAIAGPVGLVPGGVDVVIECAGVA 264 >3AEK-B nrPDB Length = 525 Score = 28.7 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 36/79 (45%), Gaps = 4/79 (5%) Query: 3 FLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTY-QNDKLKGRVEEFAAQLGSDIVL 61 +L+GKR+ + G + + A IA G E+ N ++ + AA+ G + ++ Sbjct: 277 YLTGKRVFIFGDGTHVIAAARIAAK--EVGFEVVGMGCYNREMARPLRTAAAEYGLEALI 334 Query: 62 QCD-VAEDASIDTMFAELG 79 D + + +I+ EL Sbjct: 335 TDDYLEVEKAIEAAAPELI 353 >3GFB-A nrPDB Length = 350 Score = 28.7 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 10/81 (12%), Positives = 29/81 (35%), Gaps = 8/81 (9%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLG----- 56 G ++G+ L+TG + +A+A + + ++ + ++ A Sbjct: 164 GPIAGRSTLITGAGPLGLLGIAVAKASGA--YPVIVSEPSEFRRKLAKKVGADYVVNPFE 221 Query: 57 -SDIVLQCDVAEDASIDTMFA 76 + D+ + A ++ Sbjct: 222 EDPVKFVMDITDGAGVEVFLE 242 >5VM2-A nrPDB Length = 347 Score = 28.3 bits (62), Expect = 3.1, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 19/40 (47%), Gaps = 3/40 (7%) Query: 23 GIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQ 62 +A+ + GA + + R ++F +G+DIV + Sbjct: 207 AMAEQL---GATVVINGAKEDTIARCQQFTEDMGADIVFE 243 >4WEQ-A nrPDB Length = 341 Score = 28.3 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 8/55 (14%), Positives = 21/55 (38%), Gaps = 1/55 (1%) Query: 11 VTGVASKLS-IAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCD 64 VT + + A+ + G ++ ++ ++ VE + A + + D Sbjct: 162 VTVGIMGMGVLGQDAARKLAAMGFKVIGWSRSKRVIEGVETYDAAGLDAFLGRTD 216 >2Q4B-A nrPDB Length = 253 Score = 28.3 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 27/82 (32%), Gaps = 13/82 (15%) Query: 8 RILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAE 67 +LVTG + + I +EG++ + E+ G V D+ + Sbjct: 6 TVLVTGASGRTGQ---IVYKKLKEGSDKFVAKGLVRSAQGKEKI---GGEADVFIGDITD 59 Query: 68 DASIDTMFAELGKVWPKFDGFV 89 SI+ F D V Sbjct: 60 ADSINPAFQ-------GIDALV 74 >4V8M-A1 nrPDB Length = 273 Score = 27.9 bits (61), Expect = 4.1, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 32/88 (36%), Gaps = 12/88 (13%) Query: 6 GKRILVTGVASKLSIA-----------YGIAQAMHREGAELAFTYQND-KLKGRVEEFAA 53 GK ++VTG A++ I + IA+ G E A N + + Sbjct: 175 GKVVMVTGGANRGRIGEIVSIERHPGAFDIARLKDASGHEFATRATNIFVIGKDMSSVPV 234 Query: 54 QLGSDIVLQCDVAEDASIDTMFAELGKV 81 L L+ +V ++ + AE + Sbjct: 235 TLPKQQGLRINVIQEREEKLIAAETRRT 262 >4NFY-A nrPDB Length = 307 Score = 27.9 bits (61), Expect = 4.1, Method: Composition-based stats. Identities = 12/77 (15%), Positives = 28/77 (36%), Gaps = 7/77 (9%) Query: 22 YGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDT-----MFA 76 GI + + + G E+ + K + +E G ++++ D ++ I + Sbjct: 17 KGIREILEKAGHEVVMIEKYKKKEDVIERIKDADG--VIVRSDKIDEEIIKAGEKVKIIV 74 Query: 77 ELGKVWPKFDGFVHSIG 93 G + D + G Sbjct: 75 RAGAGYDNIDIEACNQG 91 >6DKH-A nrPDB Length = 346 Score = 27.9 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 26/60 (43%), Gaps = 6/60 (10%) Query: 2 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVL 61 G L GKR+ ++GV I I A+ GA + R ++G+D+++ Sbjct: 169 GELQGKRVFISGVGP---IGCLIVSAVKTLGAAEIVCA---DVSPRSLSLGKEMGADVLV 222 >6GNF-A nrPDB Length = 544 Score = 27.9 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 8/56 (14%), Positives = 19/56 (33%), Gaps = 6/56 (10%) Query: 134 MLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISA 189 ++ GS +L + ++ E A L + + G +V ++ Sbjct: 14 LVPRGSHMLNICFVSTEVA-----PYSKT-GGLGDVTEGLPEELAKIGHKVCTVAP 63 >4FIO-A nrPDB Length = 354 Score = 27.9 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 13/47 (27%), Positives = 22/47 (46%), Gaps = 2/47 (4%) Query: 81 VWPKFDG--FVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFV 125 + KFD VH+ G AP +D D + A+ + + +Y +V Sbjct: 229 EFLKFDVKKVVHAAGIAPIAPIDPDGLKAMGKTNDAVLFGGRTYYYV 275 >4GBJ-A nrPDB Length = 297 Score = 27.9 bits (61), Expect = 5.1, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 33/89 (37%), Gaps = 11/89 (12%) Query: 20 IAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQL---------GSDIVLQCDVAEDAS 70 + IA+ + G EL + + + A + IV +A+DA+ Sbjct: 16 LGTPIAEILLEAGYELVVWNRTASKAEPLTKLGATVVENAIDAITPGGIVFSV-LADDAA 74 Query: 71 IDTMFA-ELGKVWPKFDGFVHSIGFAPGD 98 ++ +F+ EL + K V +P Sbjct: 75 VEELFSMELVEKLGKDGVHVSMSTISPET 103 >5B4F-A nrPDB Length = 329 Score = 27.9 bits (61), Expect = 5.3, Method: Composition-based stats. Identities = 14/48 (29%), Positives = 18/48 (37%), Gaps = 3/48 (6%) Query: 1 MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRV 48 + LSG+ A LS Y I Q EG + T N + V Sbjct: 121 LARLSGRVAC---SACGLSKRYIINQVAVEEGFRVVATGHNLDDEAAV 165 >3DQQ-A nrPDB Length = 421 Score = 27.5 bits (60), Expect = 5.6, Method: Composition-based stats. Identities = 9/50 (18%), Positives = 18/50 (36%) Query: 141 LLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAG 190 + + A AI A ++EA +A + G+ ++ G Sbjct: 313 ISATASTQALAAIQQQYGATEASHAVEALFSLLAARLAEGGITRFIVAGG 362 >3FBG-A nrPDB Length = 346 Score = 27.5 bits (60), Expect = 5.7, Method: Composition-based stats. Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 8/58 (13%) Query: 5 SGKRILVTGVASKLS-IAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVL 61 GK +L+ A + IA IA+A G + T + E+ ++G+DIVL Sbjct: 150 EGKTLLIINGAGGVGSIATQIAKAY---GLRVITT----ASRNETIEWTKKMGADIVL 200 >2RKB-A nrPDB Length = 318 Score = 27.5 bits (60), Expect = 6.1, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 21/42 (50%), Gaps = 1/42 (2%) Query: 24 IAQAMHREGAELAFTYQN-DKLKGRVEEFAAQLGSDIVLQCD 64 + Q + EGAE+ T + D+ R +E A + G + V D Sbjct: 92 VVQRLQGEGAEVQLTGKVWDEANLRAQELAKRDGWENVPPFD 133 >3LNU-A nrPDB Length = 408 Score = 27.5 bits (60), Expect = 6.5, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 22/57 (38%), Gaps = 9/57 (15%) Query: 178 GPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCS 234 G VN + +G T A DFR +L + P EDV + F+ S Sbjct: 292 AQHGTHVNGLRSGL--TDALREFCDFRNLLPRGVKLAP-------EDVWDRVTFVLS 339 >1YXY-A nrPDB Length = 234 Score = 27.1 bits (59), Expect = 6.9, Method: Composition-based stats. Identities = 8/51 (15%), Positives = 19/51 (37%), Gaps = 7/51 (13%) Query: 137 PGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAI 187 G ++ + +A+P + + + A G G+R N++ Sbjct: 15 KGGIIV------SCQALPGEPLYSET-GGIMPLMAKAAQEAGAVGIRANSV 58 >1SOW-A nrPDB Length = 328 Score = 27.1 bits (59), Expect = 7.1, Method: Composition-based stats. Identities = 21/141 (14%), Positives = 45/141 (31%), Gaps = 1/141 (0%) Query: 33 AELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSI 92 + T D + E + + + +V + A A+ ++ P+ D I Sbjct: 125 FVIVVTNPLDCMVKCFHEASGLPKNMVCGMANVLDSARFRRFIADQLEISPR-DIQATVI 183 Query: 93 GFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERA 152 G L V + + +A+ G ++ L G+ Sbjct: 184 GTHGDHMLPLARYVTVNGFPLREFIKKGKMTEAKLAEIVERTKKAGGEIVRLLGQGSAYY 243 Query: 153 IPNYNVMGLAKASLEANVRYM 173 P + + +A+A L+ R + Sbjct: 244 APALSAITMAQAFLKDEKRVL 264 >4J6F-A nrPDB Length = 382 Score = 27.1 bits (59), Expect = 7.2, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 26/69 (37%), Gaps = 4/69 (5%) Query: 5 SGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCD 64 +G+ +LVTG + + I Q GA + + + + AQ Q D Sbjct: 206 AGETVLVTGASG--GVGSAIIQLARARGA-VPIAVAGPGKEAAMLDIGAQ-AVVTRGQGD 261 Query: 65 VAEDASIDT 73 +AE + Sbjct: 262 LAEAVEAAS 270 >2RIR-A nrPDB Length = 300 Score = 27.1 bits (59), Expect = 7.3, Method: Composition-based stats. Identities = 9/47 (19%), Positives = 17/47 (36%), Gaps = 3/47 (6%) Query: 6 GKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFA 52 G ++ V G+ IA+ GA + ++ R+ E Sbjct: 157 GSQVAVLGLGRT---GMTIARTFAALGANVKVGARSSAHLARITEMG 200 >5LZL-A nrPDB Length = 338 Score = 27.1 bits (59), Expect = 7.8, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 19/44 (43%) Query: 7 KRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEE 50 K G + +I I A+ R GA+L TY + ++E Sbjct: 291 KAAATAGYVDERTITLEILTAIKRAGADLILTYHALEAAKWIKE 334 >4N18-A nrPDB Length = 332 Score = 27.1 bits (59), Expect = 8.1, Method: Composition-based stats. Identities = 11/80 (13%), Positives = 22/80 (27%), Gaps = 24/80 (30%) Query: 11 VTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDAS 70 + G+ I IA + R G ++ +++K V + Sbjct: 161 IMGLGE---IGGYIADQLARLGYRVSGWSRSEKQLAGV---------------------T 196 Query: 71 IDTMFAELGKVWPKFDGFVH 90 L DG ++ Sbjct: 197 CYRGEEALDHFLGSLDGLIN 216 >4AY7-A nrPDB Length = 348 Score = 27.1 bits (59), Expect = 8.2, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 28/78 (35%), Gaps = 6/78 (7%) Query: 42 DKLKGRVEEFAAQLGSDIVLQCDVAEDAS-----IDTMFAELGKVW-PKFDGFVHSIGFA 95 ++ G ++ +G+ L +V+ + +D + AE + D G A Sbjct: 269 EEKIGSAKKGKEVIGTRARLVGNVSSPFTLLPGPVDKIKAEAKEALEGGIDVLAPGCGIA 328 Query: 96 PGDQLDGDYVNAVTREGF 113 P L+ R+ F Sbjct: 329 PMTPLENVKALVAARDEF 346 >5F5N-A nrPDB Length = 289 Score = 27.1 bits (59), Expect = 8.4, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 27/77 (35%), Gaps = 5/77 (6%) Query: 6 GKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDV 65 + ILVTG +A+ G + + G A ++ D+ Sbjct: 1 NRTILVTGATGTQG--GATVRALLARGRPV---RALVRDPGTDAARALAAAGVSLVTGDL 55 Query: 66 AEDASIDTMFAELGKVW 82 + AS+ A++ V+ Sbjct: 56 NDQASLRAAMADVHGVF 72 >2VN8-A nrPDB Length = 375 Score = 27.1 bits (59), Expect = 8.5, Method: Composition-based stats. Identities = 22/89 (24%), Positives = 35/89 (39%), Gaps = 14/89 (15%) Query: 5 SGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCD 64 +GKR+L+ G + + + I Q M A + D E +LG+D D Sbjct: 183 TGKRVLILGASGGVG-TFAI-QVMKAWDAHVTAVCSQD-----ASELVRKLGAD-----D 230 Query: 65 VAEDASIDTMFAELGKVWPKFDGFVHSIG 93 V + S E K FD + ++G Sbjct: 231 VIDYKS--GSVEEQLKSLKPFDFILDNVG 257 >6H5E-B nrPDB Length = 437 Score = 27.1 bits (59), Expect = 8.9, Method: Composition-based stats. Identities = 4/21 (19%), Positives = 9/21 (42%) Query: 73 TMFAELGKVWPKFDGFVHSIG 93 F + + + D V++I Sbjct: 130 NFFRDQMDRFGEIDIMVNNIA 150 >1O89-A nrPDB Length = 345 Score = 26.7 bits (58), Expect = 9.2, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 25/56 (44%), Gaps = 6/56 (10%) Query: 9 ILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCD 64 I+VTG + + + +A +H+ G ++ + E+ LG+ VL D Sbjct: 171 IVVTGASGGVG-STAVAL-LHKLGYQVVAVSGRES----THEYLKSLGASRVLPRD 220 >1T9K-A nrPDB Length = 347 Score = 26.7 bits (58), Expect = 9.4, Method: Composition-based stats. Identities = 21/124 (16%), Positives = 45/124 (36%), Gaps = 23/124 (18%) Query: 101 DGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMG 160 + + E K+A++ + A+ K ++ GS +LT GA + +G Sbjct: 113 RENLFEILENEALKMAYEDIEVN-KAIGKNGAQLIKDGSTILTHCNAGALATVDYGTALG 171 Query: 161 LAKASLEA----------------NVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFR 204 + +A++E+ R A + +G+ V + T +G R Sbjct: 172 VIRAAVESGKRIRVFADETRPYLQGARLTAWELMKDGIEV------YVITDNMAGWLMKR 225 Query: 205 KMLA 208 ++ Sbjct: 226 GLID 229 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.314 0.156 0.440 Lambda K H 0.267 0.0477 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,827,436 Number of Sequences: 36641 Number of extensions: 457490 Number of successful extensions: 2820 Number of sequences better than 10.0: 322 Number of HSP's better than 10.0 without gapping: 321 Number of HSP's successfully gapped in prelim test: 151 Number of HSP's that attempted gapping in prelim test: 1775 Number of HSP's gapped (non-prelim): 507 length of query: 262 length of database: 10,336,785 effective HSP length: 95 effective length of query: 167 effective length of database: 6,855,890 effective search space: 1144933630 effective search space used: 1144933630 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.1 bits)