BLASTP 2.2.23 [Feb-03-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= P0AEE3
         (355 letters)

Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 
           36,641 sequences; 10,336,785 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

3GCO-A nrPDB                                                          645   0.0  
2QF3-A nrPDB                                                          460   e-130
5JD8-A nrPDB                                                          456   e-129
2R3U-A nrPDB                                                          419   e-118
3STJ-A nrPDB                                                          209   1e-54
4A8B-A nrPDB                                                          207   5e-54
3MH6-A nrPDB                                                          204   6e-53
5Y2D-A nrPDB                                                          197   6e-51
5Y28-A nrPDB                                                          197   6e-51
3PV2-A nrPDB                                                          193   1e-49
3PV4-A nrPDB                                                          192   1e-49
4YNN-A nrPDB                                                          191   3e-49
4YO1-A nrPDB                                                          191   4e-49
5T69-A nrPDB                                                          162   2e-40
3STI-A nrPDB                                                          158   4e-39
3QO6-A nrPDB                                                          158   4e-39
6IEO-A nrPDB                                                          150   8e-37
4RI0-A nrPDB                                                          142   2e-34
3NUM-A nrPDB                                                          139   1e-33
4IC6-A nrPDB                                                          135   3e-32
1L1J-A nrPDB                                                          129   2e-30
2Z9I-A nrPDB                                                          117   9e-27
3TJO-A nrPDB                                                          114   7e-26
5M3O-A nrPDB                                                          113   1e-25
4IC5-A nrPDB                                                          100   7e-22
5ILB-A nrPDB                                                           65   6e-11
4FLN-A nrPDB                                                           64   7e-11
5HM9-A nrPDB                                                           52   3e-07
5JYK-A nrPDB                                                           52   6e-07
5ILA-A nrPDB                                                           45   5e-05
4FGM-A nrPDB                                                           39   0.004
2KJP-A nrPDB                                                           37   0.010
5C2Z-A nrPDB                                                           34   0.11 
2VZ5-A nrPDB                                                           33   0.15 
3LT3-A nrPDB                                                           33   0.20 
2L4S-A nrPDB                                                           33   0.27 
1VRA-B nrPDB                                                           32   0.33 
4O06-A nrPDB                                                           31   0.87 
5KAY-A nrPDB                                                           30   1.5  
6A9U-A nrPDB                                                           30   1.6  
1WCZ-A nrPDB                                                           29   2.8  
4C2G-A nrPDB                                                           29   3.2  
2AS9-A nrPDB                                                           29   3.7  
1DT2-A nrPDB                                                           28   4.1  
2V90-A nrPDB                                                           28   5.2  
5JWG-A nrPDB                                                           28   5.3  
2W7U-A nrPDB                                                           28   5.3  
5MM8-A nrPDB                                                           28   5.7  
3WYB-A nrPDB                                                           28   5.7  
4K1S-A nrPDB                                                           28   6.2  
4XZY-A nrPDB                                                           28   6.2  
4DLL-A nrPDB                                                           28   6.4  
1FC9-A nrPDB                                                           28   7.3  
3EGH-C nrPDB                                                           27   9.7  
5ZDS-A nrPDB                                                           27   9.9  

>3GCO-A nrPDB
          Length = 340

 Score =  645 bits (1665), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 327/329 (99%), Positives = 327/329 (99%)

Query: 27  RSLNPLSTPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMD 86
           RSLNPLSTPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMD
Sbjct: 12  RSLNPLSTPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMD 71

Query: 87  QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINAR 146
           QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINAR
Sbjct: 72  QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINAR 131

Query: 147 RVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALV 206
           RVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASIN GNSGGALV
Sbjct: 132 RVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINPGNSGGALV 191

Query: 207 NSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREI 266
           NSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREI
Sbjct: 192 NSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREI 251

Query: 267 APLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIR 326
           APLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETM QVAEIR
Sbjct: 252 APLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMAQVAEIR 311

Query: 327 PGSVIPVVVMRDDKQLTLQVTIQEYPATN 355
           PGSVIPVVVMRDDKQLTLQVTIQEYPATN
Sbjct: 312 PGSVIPVVVMRDDKQLTLQVTIQEYPATN 340


>2QF3-A nrPDB
          Length = 243

 Score =  460 bits (1183), Expect = e-130,   Method: Compositional matrix adjust.
 Identities = 230/230 (100%), Positives = 230/230 (100%)

Query: 27  RSLNPLSTPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMD 86
           RSLNPLSTPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMD
Sbjct: 14  RSLNPLSTPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMD 73

Query: 87  QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINAR 146
           QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINAR
Sbjct: 74  QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINAR 133

Query: 147 RVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALV 206
           RVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALV
Sbjct: 134 RVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALV 193

Query: 207 NSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIR 256
           NSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIR
Sbjct: 194 NSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIR 243


>5JD8-A nrPDB
          Length = 334

 Score =  456 bits (1174), Expect = e-129,   Method: Compositional matrix adjust.
 Identities = 229/310 (73%), Positives = 266/310 (85%), Gaps = 2/310 (0%)

Query: 41  DETPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVIND 100
           +E P SYN AVRRAAPAVVNVYNR L+  +   L IRTLGSGVIM  +GYI+TNKHVIND
Sbjct: 14  EEVPTSYNQAVRRAAPAVVNVYNRSLSA-TQQGLAIRTLGSGVIMSDKGYILTNKHVIND 72

Query: 101 ADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGN 160
           A+QIIVA+Q+GR+ EALLVGSD+LTDLAVLKI+AT  LP IPIN  R PHIGDVVLAIGN
Sbjct: 73  AEQIIVAMQNGRISEALLVGSDNLTDLAVLKIDATN-LPVIPININRTPHIGDVVLAIGN 131

Query: 161 PYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTLSF 220
           PYNLGQT+TQGIISATGRIGL+ +GRQNFLQTDASIN GNSGGALVN+LGELMGINTLSF
Sbjct: 132 PYNLGQTVTQGIISATGRIGLSSSGRQNFLQTDASINQGNSGGALVNTLGELMGINTLSF 191

Query: 221 DKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREIAPLHAQGGGIDQLQ 280
           DKSN+GETPEGIGFAIP  LATK+M+KLIRDGRVIRGYIGI G E  P +A   G D++ 
Sbjct: 192 DKSNNGETPEGIGFAIPTALATKVMEKLIRDGRVIRGYIGITGEEYPPFNANDNGSDRVH 251

Query: 281 GIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDDK 340
           GI V +VSPDGPAA AGI V D+I++V+NKPA S +ETMDQVAE+RPG+ IPV+++R+ +
Sbjct: 252 GIKVKKVSPDGPAAQAGIHVGDIILNVNNKPATSVIETMDQVAEVRPGTTIPVLLLRNGQ 311

Query: 341 QLTLQVTIQE 350
           Q+ +Q+TI E
Sbjct: 312 QIAVQITITE 321


>2R3U-A nrPDB
          Length = 211

 Score =  419 bits (1078), Expect = e-118,   Method: Compositional matrix adjust.
 Identities = 210/210 (100%), Positives = 210/210 (100%)

Query: 43  TPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDAD 102
           TPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDAD
Sbjct: 2   TPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDAD 61

Query: 103 QIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGNPY 162
           QIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGNPY
Sbjct: 62  QIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGNPY 121

Query: 163 NLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTLSFDK 222
           NLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTLSFDK
Sbjct: 122 NLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTLSFDK 181

Query: 223 SNDGETPEGIGFAIPFQLATKIMDKLIRDG 252
           SNDGETPEGIGFAIPFQLATKIMDKLIRDG
Sbjct: 182 SNDGETPEGIGFAIPFQLATKIMDKLIRDG 211


>3STJ-A nrPDB
          Length = 345

 Score =  209 bits (532), Expect = 1e-54,   Method: Compositional matrix adjust.
 Identities = 121/271 (44%), Positives = 171/271 (63%), Gaps = 4/271 (1%)

Query: 79  LGSGVIMD-QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGG 137
           LGSGVI++  +GY++TN HVIN A +I + L DGR F+A L+GSD  +D+A+L+I     
Sbjct: 64  LGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSK 123

Query: 138 LPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASIN 197
           L  I I       +GD  +A+GNP+ LGQT T GI+SA GR GLN  G +NF+QTDASIN
Sbjct: 124 LTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASIN 183

Query: 198 HGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRG 257
            GNSGGAL+N  GEL+GINT        G    GIGFAIP  +A  +  +LI  G + RG
Sbjct: 184 RGNSGGALLNLNGELIGINTAILAP---GGGSVGIGFAIPSNMARTLAQQLIDFGEIKRG 240

Query: 258 YIGIGGREIAPLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALE 317
            +GI G E++   A+   +D  +G  V+EV P   +A AG++  D+I S++ KP  S  E
Sbjct: 241 LLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAE 300

Query: 318 TMDQVAEIRPGSVIPVVVMRDDKQLTLQVTI 348
              ++A   PG+ + + ++R+ K L ++VT+
Sbjct: 301 LRSRIATTEPGTKVKLGLLRNGKPLEVEVTL 331


>4A8B-A nrPDB
          Length = 436

 Score =  207 bits (528), Expect = 5e-54,   Method: Compositional matrix adjust.
 Identities = 120/271 (44%), Positives = 171/271 (63%), Gaps = 4/271 (1%)

Query: 79  LGSGVIMD-QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGG 137
           LGSGVI++  +GY++TN HVIN A +I + L DGR F+A L+GSD  +D+A+L+I     
Sbjct: 64  LGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSK 123

Query: 138 LPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASIN 197
           L  I I       +GD  +A+GNP+ LGQT T GI+SA GR GLN  G +NF+QTDASIN
Sbjct: 124 LTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASIN 183

Query: 198 HGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRG 257
            GN+GGAL+N  GEL+GINT        G    GIGFAIP  +A  +  +LI  G + RG
Sbjct: 184 RGNAGGALLNLNGELIGINTAILAP---GGGSVGIGFAIPSNMARTLAQQLIDFGEIKRG 240

Query: 258 YIGIGGREIAPLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALE 317
            +GI G E++   A+   +D  +G  V+EV P   +A AG++  D+I S++ KP  S  E
Sbjct: 241 LLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAE 300

Query: 318 TMDQVAEIRPGSVIPVVVMRDDKQLTLQVTI 348
              ++A   PG+ + + ++R+ K L ++VT+
Sbjct: 301 LRSRIATTEPGTKVKLGLLRNGKPLEVEVTL 331



 Score = 37.4 bits (85), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 21/70 (30%), Positives = 45/70 (64%), Gaps = 2/70 (2%)

Query: 280 QGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDD 339
           +GI ++EV    PAA AG+Q +D+II V N+  ++++  M +V   +P ++I + ++R +
Sbjct: 363 KGIKIDEVVKGSPAAQAGLQKDDVIIGV-NRDRVNSIAEMRKVLAAKP-AIIALQIVRGN 420

Query: 340 KQLTLQVTIQ 349
           + + L + ++
Sbjct: 421 ESIYLLMRLE 430


>3MH6-A nrPDB
          Length = 456

 Score =  204 bits (518), Expect = 6e-53,   Method: Compositional matrix adjust.
 Identities = 118/279 (42%), Positives = 173/279 (62%), Gaps = 8/279 (2%)

Query: 75  EIRTLGSGVIMD-QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKIN 133
           +   LGSGVI+D  +GY++TN HV+++A  I V L DGR F+A +VG D  +D+A+++I 
Sbjct: 83  KFMALGSGVIIDADKGYVVTNNHVVDNATVIKVQLSDGRKFDAKMVGKDPRSDIALIQIQ 142

Query: 134 ATGGLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTD 193
               L  I +       +GD  +AIGNP+ LG+T+T GI+SA GR GLN    +NF+QTD
Sbjct: 143 NPKNLTAIKMADSDALRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLNAENYENFIQTD 202

Query: 194 ASINHGNSGGALVNSLGELMGINT--LSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRD 251
           A+IN GNSGGALVN  GEL+GINT  L+ D  N      GIGFAIP  +   +  +++  
Sbjct: 203 AAINRGNSGGALVNLNGELIGINTAILAPDGGN-----IGIGFAIPSNMVKNLTSQMVEY 257

Query: 252 GRVIRGYIGIGGREIAPLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKP 311
           G+V RG +GI G E+    A+   +D  +G  V++V P+  AA AGI+  D+I S++ KP
Sbjct: 258 GQVKRGELGIMGTELNSELAKAMKVDAQRGAFVSQVLPNSSAAKAGIKAGDVITSLNGKP 317

Query: 312 AISALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQE 350
             S      QV  +  GS + + ++RD KQ+ + + +Q+
Sbjct: 318 ISSFAALRAQVGTMPVGSKLTLGLLRDGKQVNVNLELQQ 356



 Score = 34.7 bits (78), Expect = 0.060,   Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 37/65 (56%), Gaps = 2/65 (3%)

Query: 280 QGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDD 339
           QG+VVN V    PAA  G++  D+II   N+ A+  +  + +V + +P SV+ + + R D
Sbjct: 383 QGVVVNNVKTGTPAAQIGLKKGDVIIGA-NQQAVKNIAELRKVLDSKP-SVLALNIQRGD 440

Query: 340 KQLTL 344
             + L
Sbjct: 441 STIYL 445


>5Y2D-A nrPDB
          Length = 465

 Score =  197 bits (501), Expect = 6e-51,   Method: Compositional matrix adjust.
 Identities = 132/365 (36%), Positives = 200/365 (54%), Gaps = 37/365 (10%)

Query: 16  GAILLVAMPSLRSLNPLSTPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTNS----- 70
           G I + +MP ++    +S P   S D+T  SY+ +++ +  AVVN+       N+     
Sbjct: 8   GNIQIQSMPKVKER--VSVP---SKDDTIYSYHDSIKDSIKAVVNISTEKKIKNNFIGGG 62

Query: 71  -------------------HNQLEIRTLGSGVIMDQRGYIITNKHVINDADQIIVALQ-D 110
                                ++E R LGSGVI+ + GYI+TN HVI+ AD+I V +   
Sbjct: 63  VFNDPFFQQFFGDLGGMIPKERME-RALGSGVIISKDGYIVTNNHVIDGADKIKVTIPGS 121

Query: 111 GRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQ 170
            + + A LVG+DS +DLAV++I     LPTI  +      +GD+V AIGNP+ +G+++TQ
Sbjct: 122 NKEYSATLVGTDSESDLAVIRITKDN-LPTIKFSDSNDISVGDLVFAIGNPFGVGESVTQ 180

Query: 171 GIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPE 230
           GI+SA  + G+     +NF+QTDASIN GNSGGAL++S G L+GINT    K+       
Sbjct: 181 GIVSALNKSGIGINSYENFIQTDASINPGNSGGALIDSRGGLVGINTAIISKTGGN---H 237

Query: 231 GIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREIAPLHAQGGGIDQLQGIVVNEVSPD 290
           GIGFAIP  +    + +LI+ G++ RGY+G+G ++++         D  +G VV  V  D
Sbjct: 238 GIGFAIPSNMVKDTVTQLIKTGKIERGYLGVGLQDLSGDLQN--SYDNKEGAVVISVEKD 295

Query: 291 GPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQE 350
            PA  AGI V DLI  V+ K   +  E  + +  + P   + + V+RD K+    +T+ E
Sbjct: 296 SPAKKAGILVWDLITEVNGKKVKNTNELRNLIGSMLPNQRVTLKVIRDKKERAFTLTLAE 355

Query: 351 YPATN 355
               N
Sbjct: 356 RKNPN 360


>5Y28-A nrPDB
          Length = 357

 Score =  197 bits (501), Expect = 6e-51,   Method: Compositional matrix adjust.
 Identities = 131/360 (36%), Positives = 199/360 (55%), Gaps = 37/360 (10%)

Query: 16  GAILLVAMPSLRSLNPLSTPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTNS----- 70
           G I + +MP ++    +S P   S D+T  SY+ +++ +  AVVN+       N+     
Sbjct: 8   GNIQIQSMPKVKER--VSVP---SKDDTIYSYHDSIKDSIKAVVNISTEKKIKNNFIGGG 62

Query: 71  -------------------HNQLEIRTLGSGVIMDQRGYIITNKHVINDADQIIVALQ-D 110
                                ++E R LGSGVI+ + GYI+TN HVI+ AD+I V +   
Sbjct: 63  VFNDPFFQQFFGDLGGMIPKERME-RALGSGVIISKDGYIVTNNHVIDGADKIKVTIPGS 121

Query: 111 GRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQ 170
            + + A LVG+DS +DLAV++I     LPTI  +      +GD+V AIGNP+ +G+++TQ
Sbjct: 122 NKEYSATLVGTDSESDLAVIRITKDN-LPTIKFSDSNDISVGDLVFAIGNPFGVGESVTQ 180

Query: 171 GIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPE 230
           GI+SA  + G+     +NF+QTDASIN GNSGGAL++S G L+GINT    K+       
Sbjct: 181 GIVSALNKSGIGINSYENFIQTDASINPGNSGGALIDSRGGLVGINTAIISKTGGN---H 237

Query: 231 GIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREIAPLHAQGGGIDQLQGIVVNEVSPD 290
           GIGFAIP  +    + +LI+ G++ RGY+G+G ++++         D  +G VV  V  D
Sbjct: 238 GIGFAIPSNMVKDTVTQLIKTGKIERGYLGVGLQDLSGDLQN--SYDNKEGAVVISVEKD 295

Query: 291 GPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQE 350
            PA  AGI V DLI  V+ K   +  E  + +  + P   + + V+RD K+    +T+ E
Sbjct: 296 SPAKKAGILVWDLITEVNGKKVKNTNELRNLIGSMLPNQRVTLKVIRDKKERAFTLTLAE 355


>3PV2-A nrPDB
          Length = 451

 Score =  193 bits (490), Expect = 1e-49,   Method: Compositional matrix adjust.
 Identities = 123/285 (43%), Positives = 174/285 (61%), Gaps = 15/285 (5%)

Query: 75  EIRTLGSGVIMD-QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKIN 133
           +  ++GSGVI+D   G IITN HVI +A  I V LQDGR  +A L+G DS TDLAVLKI+
Sbjct: 74  KFESIGSGVIIDPNNGVIITNDHVIRNASLITVTLQDGRRLKARLIGGDSETDLAVLKID 133

Query: 134 ATGGLPTIPINARRVPHIGDVVLAIGNPYNL-----GQTITQGIISATGRIGLNPTGRQN 188
           A   L ++ I       +GD V+AIGNP+ L      Q+ T GI+SA  R  LN  G +N
Sbjct: 134 AKN-LKSLVIGDSDKLEVGDFVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVEN 192

Query: 189 FLQTDASINHGNSGGALVNSLGELMGINT--LSFDKSNDGETPEGIGFAIPFQLATKIMD 246
           F+QTDA+IN GNSGGALVN+ GEL+GINT  LS    N      GIGFAIP  +   +  
Sbjct: 193 FIQTDAAINPGNSGGALVNAKGELIGINTAILSPYGGN-----VGIGFAIPINMVKDVAQ 247

Query: 247 KLIRDGRVIRGYIGIGGREIAPLHAQGGGI-DQLQGIVVNEVSPDGPAANAGIQVNDLII 305
           ++I+ G + RG +GI  + + P  AQ  G  +  QG +V++V+P+ PA  AG++  D+I 
Sbjct: 248 QIIKFGSIHRGLMGIFVQHLTPELAQAMGYPEDFQGALVSQVNPNSPAELAGLKAGDIIT 307

Query: 306 SVDNKPAISALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQE 350
            +++     A +    ++ +R GS + ++V RD+K LTL   + +
Sbjct: 308 QINDTKITQATQVKTTISLLRVGSTVKIIVERDNKPLTLSAVVTD 352


>3PV4-A nrPDB
          Length = 354

 Score =  192 bits (489), Expect = 1e-49,   Method: Compositional matrix adjust.
 Identities = 123/285 (43%), Positives = 174/285 (61%), Gaps = 15/285 (5%)

Query: 75  EIRTLGSGVIMD-QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKIN 133
           +  ++GSGVI+D   G IITN HVI +A  I V LQDGR  +A L+G DS TDLAVLKI+
Sbjct: 74  KFESIGSGVIIDPNNGVIITNDHVIRNASLITVTLQDGRRLKARLIGGDSETDLAVLKID 133

Query: 134 ATGGLPTIPINARRVPHIGDVVLAIGNPYNL-----GQTITQGIISATGRIGLNPTGRQN 188
           A   L ++ I       +GD V+AIGNP+ L      Q+ T GI+SA  R  LN  G +N
Sbjct: 134 AKN-LKSLVIGDSDKLEVGDFVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVEN 192

Query: 189 FLQTDASINHGNSGGALVNSLGELMGINT--LSFDKSNDGETPEGIGFAIPFQLATKIMD 246
           F+QTDA+IN GNSGGALVN+ GEL+GINT  LS    N      GIGFAIP  +   +  
Sbjct: 193 FIQTDAAINPGNSGGALVNAKGELIGINTAILSPYGGN-----VGIGFAIPINMVKDVAQ 247

Query: 247 KLIRDGRVIRGYIGIGGREIAPLHAQGGGI-DQLQGIVVNEVSPDGPAANAGIQVNDLII 305
           ++I+ G + RG +GI  + + P  AQ  G  +  QG +V++V+P+ PA  AG++  D+I 
Sbjct: 248 QIIKFGSIHRGLMGIFVQHLTPELAQAMGYPEDFQGALVSQVNPNSPAELAGLKAGDIIT 307

Query: 306 SVDNKPAISALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQE 350
            +++     A +    ++ +R GS + ++V RD+K LTL   + +
Sbjct: 308 QINDTKITQATQVKTTISLLRVGSTVKIIVERDNKPLTLSAVVTD 352


>4YNN-A nrPDB
          Length = 448

 Score =  191 bits (486), Expect = 3e-49,   Method: Compositional matrix adjust.
 Identities = 119/283 (42%), Positives = 174/283 (61%), Gaps = 11/283 (3%)

Query: 75  EIRTLGSGVIMD-QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKIN 133
           +  ++GSGVI+D + G IITN HVI +A+ I V LQDGR  +A L+G DS TDLAVLKI+
Sbjct: 71  KFESIGSGVIIDPKNGIIITNDHVIRNANLITVTLQDGRRLKARLIGGDSETDLAVLKID 130

Query: 134 ATGGLPTIPINARRVPHIGDVVLAIGNPYNL-----GQTITQGIISATGRIGLNPTGRQN 188
           A   L ++ I       +GD V+AIGNP+ L      Q+ T GI+SA  R  LN  G +N
Sbjct: 131 AKN-LKSLVIGDSDKLEVGDYVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVEN 189

Query: 189 FLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKL 248
           F+QTDA+IN GN+GGALVN+ GEL+GINT             GIGFAIP  +A  +  ++
Sbjct: 190 FIQTDAAINPGNAGGALVNAKGELIGINTAIISPYGGN---VGIGFAIPINMAKDVAQQI 246

Query: 249 IRDGRVIRGYIGIGGREIAPLHAQGGGI-DQLQGIVVNEVSPDGPAANAGIQVNDLIISV 307
           I+ G + RG +GI  + + P  AQ  G  +  QG +V++V+ + PA  AG++  D+I+ +
Sbjct: 247 IKFGSIHRGLMGIFVQHLTPELAQSMGYAEDFQGALVSQVNQNSPAQLAGLKSGDVIVQI 306

Query: 308 DNKPAISALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQE 350
           ++     A +    ++ +R GS   + ++RD+K LTL V + +
Sbjct: 307 NDTKITQATQVKTTISLLRAGSTAKIKILRDNKPLTLDVEVTD 349


>4YO1-A nrPDB
          Length = 351

 Score =  191 bits (485), Expect = 4e-49,   Method: Compositional matrix adjust.
 Identities = 119/283 (42%), Positives = 174/283 (61%), Gaps = 11/283 (3%)

Query: 75  EIRTLGSGVIMD-QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKIN 133
           +  ++GSGVI+D + G IITN HVI +A+ I V LQDGR  +A L+G DS TDLAVLKI+
Sbjct: 71  KFESIGSGVIIDPKNGIIITNDHVIRNANLITVTLQDGRRLKARLIGGDSETDLAVLKID 130

Query: 134 ATGGLPTIPINARRVPHIGDVVLAIGNPYNL-----GQTITQGIISATGRIGLNPTGRQN 188
           A   L ++ I       +GD V+AIGNP+ L      Q+ T GI+SA  R  LN  G +N
Sbjct: 131 AKN-LKSLVIGDSDKLEVGDYVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVEN 189

Query: 189 FLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKL 248
           F+QTDA+IN GN+GGALVN+ GEL+GINT             GIGFAIP  +A  +  ++
Sbjct: 190 FIQTDAAINPGNAGGALVNAKGELIGINTAIISPYGGN---VGIGFAIPINMAKDVAQQI 246

Query: 249 IRDGRVIRGYIGIGGREIAPLHAQGGGI-DQLQGIVVNEVSPDGPAANAGIQVNDLIISV 307
           I+ G + RG +GI  + + P  AQ  G  +  QG +V++V+ + PA  AG++  D+I+ +
Sbjct: 247 IKFGSIHRGLMGIFVQHLTPELAQSMGYAEDFQGALVSQVNQNSPAQLAGLKSGDVIVQI 306

Query: 308 DNKPAISALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQE 350
           ++     A +    ++ +R GS   + ++RD+K LTL V + +
Sbjct: 307 NDTKITQATQVKTTISLLRAGSTAKIKILRDNKPLTLDVEVTD 349


>5T69-A nrPDB
          Length = 367

 Score =  162 bits (410), Expect = 2e-40,   Method: Compositional matrix adjust.
 Identities = 108/280 (38%), Positives = 152/280 (54%), Gaps = 20/280 (7%)

Query: 80  GSGVIMDQRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATG-GL 138
           GSG I+D  G I+TN HV++ A +++V L+DGR F+  + G+D +TDLAV+KI   G  L
Sbjct: 85  GSGFIIDNSGIILTNAHVVDGASKVVVTLRDGRTFDGQVRGTDEVTDLAVVKIEPQGSAL 144

Query: 139 PTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLN---PTGRQNFLQTDAS 195
           P  P+       +GD  +A+GNP  L  T+T GIIS  GR       P  R  F+QTDA+
Sbjct: 145 PVAPLGTSSNLQVGDWAIAVGNPVGLDNTVTLGIISTLGRSAAQAGIPDKRVEFIQTDAA 204

Query: 196 INHGNSGGALVNSLGELMGINT-LSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRV 254
           IN GN+GG L+N+ GE++GINT +  D +       GIGFAIP   A  I + L   G V
Sbjct: 205 INPGNAGGPLLNARGEVIGINTAIRADAT-------GIGFAIPIDQAKAIQNTLAAGGTV 257

Query: 255 IRGYIGIGGREIAPLHAQGGG--------IDQLQGIVVNEVSPDGPAANAGIQVNDLIIS 306
              YIG+    I    AQ           I ++ GI+V  V P  PA  AGI+  D+I++
Sbjct: 258 PHPYIGVQMMNITVDQAQQNNRNPNSPFIIPEVDGILVMRVLPGTPAERAGIRRGDVIVA 317

Query: 307 VDNKPAISALETMDQVAEIRPGSVIPVVVMRDDKQLTLQV 346
           VD  P          V +      + + ++R D++L+L V
Sbjct: 318 VDGTPISDGARLQRIVEQAGLNKALKLDLLRGDRRLSLTV 357


>3STI-A nrPDB
          Length = 245

 Score =  158 bits (399), Expect = 4e-39,   Method: Compositional matrix adjust.
 Identities = 90/179 (50%), Positives = 117/179 (65%), Gaps = 4/179 (2%)

Query: 79  LGSGVIMD-QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGG 137
           LGSGVI++  +GY++TN HVIN A +I + L DGR F+A L+GSD  +D+A+L+I     
Sbjct: 64  LGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSK 123

Query: 138 LPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASIN 197
           L  I I       +GD  +A+GNP+ LGQT T GI+SA GR GLN  G +NF+QTDASIN
Sbjct: 124 LTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASIN 183

Query: 198 HGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIR 256
            GNSGGAL+N  GEL+GINT        G    GIGFAIP  +A  +  +LI  G ++ 
Sbjct: 184 RGNSGGALLNLNGELIGINTAILAP---GGGSVGIGFAIPSNMARTLAQQLIDFGEILE 239


>3QO6-A nrPDB
          Length = 348

 Score =  158 bits (399), Expect = 4e-39,   Method: Compositional matrix adjust.
 Identities = 121/341 (35%), Positives = 185/341 (54%), Gaps = 32/341 (9%)

Query: 32  LSTPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTNSH--NQLEI-RTLGSGVIMDQR 88
           +STP+   TDE  A+  L  +   P+VV + N  +  ++   + LE+ +  GSG + D++
Sbjct: 6   VSTPKKLQTDEL-ATVRL-FQENTPSVVYITNLAVRQDAFTLDVLEVPQGSGSGFVWDKQ 63

Query: 89  GYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINA-TGGLPTIPINARR 147
           G+I+TN HVI  A  + V L D   F+A +VG D   D+AVL+I+A    L  IP+    
Sbjct: 64  GHIVTNYHVIRGASDLRVTLADQTTFDAKVVGFDQDKDVAVLRIDAPKNKLRPIPVGVSA 123

Query: 148 VPHIGDVVLAIGNPYNLGQTITQGIISATGR-IGLNPTGR--QNFLQTDASINHGNSGGA 204
              +G  V AIGNP+ L  T+T G+IS   R I    TGR  Q+ +QTDA+IN GNSGG 
Sbjct: 124 DLLVGQKVFAIGNPFGLDHTLTTGVISGLRREISSAATGRPIQDVIQTDAAINPGNSGGP 183

Query: 205 LVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGR 264
           L++S G L+GINT  +  S       G+GF+IP      I+D+L+R G+V R  +GI   
Sbjct: 184 LLDSSGTLIGINTAIYSPSG---ASSGVGFSIPVDTVGGIVDQLVRFGKVTRPILGI--- 237

Query: 265 EIAPLHAQGGGIDQL--QGIVVNEVSPDGPAANAGIQ-----------VNDLIISVDNKP 311
           + AP  +    ++QL   G++V +  P GPA  AG+Q           + D+I SV+   
Sbjct: 238 KFAPDQS----VEQLGVSGVLVLDAPPSGPAGKAGLQSTKRDGYGRLVLGDIITSVNGTK 293

Query: 312 AISALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQEYP 352
             +  +    + + + G  + V V+R D +  + VT++  P
Sbjct: 294 VSNGSDLYRILDQCKVGDEVTVEVLRGDHKEKISVTLEPKP 334


>6IEO-A nrPDB
          Length = 314

 Score =  150 bits (379), Expect = 8e-37,   Method: Compositional matrix adjust.
 Identities = 104/279 (37%), Positives = 150/279 (53%), Gaps = 23/279 (8%)

Query: 80  GSGVIMDQRGYIITNKHVINDAD------QIIVALQDGRVFEALLVGSDSLTDLAVLKIN 133
           GSGVI+D RGYI+TN HVI++A       +  V   DG+   A LVG D  TDLAVLK++
Sbjct: 32  GSGVIVDGRGYIVTNNHVISEAANNPSQFKTTVVFNDGKEVPANLVGRDPKTDLAVLKVD 91

Query: 134 ATGGLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGR-IGLNPTGRQ----- 187
               L    +       +GD VLA+G P  L  T+TQGI+SA  R + L+  G       
Sbjct: 92  NVDNLTVARLGDSSKVRVGDEVLAVGAPLGLRSTVTQGIVSALHRPVPLSGEGSDTDTVI 151

Query: 188 NFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDK 247
           + +QTDASINHGNSGG L++   +++GINT     S   ++  G+GFAIP      + + 
Sbjct: 152 DAIQTDASINHGNSGGPLIDMDAQVIGINTAGKSLS---DSASGLGFAIPVNEMKLVANS 208

Query: 248 LIRDGRVIRGYIGIGGREIAPLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISV 307
           LI+DG+++   +GI  R ++   A G          V  V    PA   GI  ND+I+ V
Sbjct: 209 LIKDGKIVHPTLGISTRSVSNAIASGAQ--------VANVKAGSPAQKGGILENDVIVKV 260

Query: 308 DNKPAISALETMDQVAEIRPGSVIPVVVMRDDKQLTLQV 346
            N+    + E +  V ++  G   P+ V+R+ + +TL V
Sbjct: 261 GNRAVADSDEFVVAVRQLAIGQDAPIEVVREGRHVTLTV 299


>4RI0-A nrPDB
          Length = 332

 Score =  142 bits (358), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 117/351 (33%), Positives = 175/351 (49%), Gaps = 70/351 (19%)

Query: 29  LNPLSTPQFDSTDETPASYNL---AVRRAAPAVVNV--------YNRGLNTNSHNQLEIR 77
           L+ LS+P++         +N     V + APAVV++        + R +  +S       
Sbjct: 1   LHQLSSPRY--------KFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSS------- 45

Query: 78  TLGSGVIMDQRGYIITNKHVIND------ADQIIVALQDGRVFEALLVGSDSLTDLAVLK 131
             GSG IM + G IITN HV++         Q+ V LQ+G  +EA +   D  +D+A +K
Sbjct: 46  --GSGFIMSEAGLIITNAHVVSSNSAAPGRQQLKVQLQNGDSYEATIKDIDKKSDIATIK 103

Query: 132 INATGGLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQ---N 188
           I+    LP + +        G+ V+AIG+P+ L  T+T GI+S   R G     R    +
Sbjct: 104 IHPKKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQREGRELGLRDSDMD 163

Query: 189 FLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIP----FQLATKI 244
           ++QTDA IN+GN+GG LVN  GE++GINTL        +   GI FAIP     +  T+ 
Sbjct: 164 YIQTDAIINYGNAGGPLVNLDGEVIGINTL--------KVTAGISFAIPSDRITRFLTEF 215

Query: 245 MDKLIRDGRVIRGYIGIGGREIAP-----LHAQGGGIDQL-QGIVVNEVSPDGPAANAGI 298
            DK I+D +  + +IGI  R I P     L A      ++  GI V EV+P+ P+   GI
Sbjct: 216 QDKQIKDWK--KRFIGIRMRTITPSLVDELKASNPDFPEVSSGIYVQEVAPNSPSQRGGI 273

Query: 299 QVNDLIISVDNKPAISALETMDQV-------AEIRPG------SVIPVVVM 336
           Q  D+I+ V+ +P + + E  + V        E+R G      S+ P VVM
Sbjct: 274 QDGDIIVKVNGRPLVDSSELQEAVLTESPLLLEVRRGNDDLLFSIAPEVVM 324


>3NUM-A nrPDB
          Length = 332

 Score =  139 bits (351), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 108/326 (33%), Positives = 175/326 (53%), Gaps = 37/326 (11%)

Query: 46  SYNL---AVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDAD 102
            YN     V + APAVV++        S  ++ + + GSG I+ + G I+TN HV+ +  
Sbjct: 12  KYNFIADVVEKIAPAVVHIELFRKLPFSKREVPVAS-GSGFIVSEDGLIVTNAHVVTNKH 70

Query: 103 QIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGNPY 162
           ++ V L++G  +EA +   D   D+A++KI+  G LP + +        G+ V+AIG+P+
Sbjct: 71  RVKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRPGEFVVAIGSPF 130

Query: 163 NLGQTITQGIISATGR----IGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTL 218
           +L  T+T GI+S T R    +GL  +   +++QTDA IN+GN+GG LVN  GE++GINTL
Sbjct: 131 SLQNTVTTGIVSTTQRGGKELGLRNSD-MDYIQTDAIINYGNAGGPLVNLDGEVIGINTL 189

Query: 219 SFDKSNDGETPEGIGFAIPF----QLATKIMDKLIRDGRVI--RGYIGI--------GGR 264
                   +   GI FAIP     +  T+  D+  + G+ I  + YIGI          +
Sbjct: 190 --------KVTAGISFAIPSDKIKKFLTESHDRQAK-GKAITKKKYIGIRMMSLTSSKAK 240

Query: 265 EIAPLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAE 324
           E+   H      D + G  + EV PD PA   G++ ND+IIS++ +  +SA +  D    
Sbjct: 241 ELKDRHRDFP--DVISGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVSANDVSDV--- 295

Query: 325 IRPGSVIPVVVMRDDKQLTLQVTIQE 350
           I+  S + +VV R ++ + + V  +E
Sbjct: 296 IKRESTLNMVVRRGNEDIMITVIPEE 321


>4IC6-A nrPDB
          Length = 368

 Score =  135 bits (340), Expect = 3e-32,   Method: Compositional matrix adjust.
 Identities = 104/297 (35%), Positives = 159/297 (53%), Gaps = 32/297 (10%)

Query: 80  GSGVIMDQRGYIITNKHVINDA-----------DQIIVALQDG--RVFEALLVGSDSLTD 126
           GSGV+ D +GYI+TN HVI +A            ++ +   DG  + FE  LVG+D   D
Sbjct: 67  GSGVVWDGQGYIVTNYHVIGNALSRNPSPGDVVGRVNILASDGVQKNFEGKLVGADRAKD 126

Query: 127 LAVLKINATGGL-PTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTG 185
           LAVLK++A   L   I +       +G   LAIGNP+    T+T G+IS   R   + TG
Sbjct: 127 LAVLKVDAPETLLKPIKVGQSNSLKVGQQCLAIGNPFGFDHTLTVGVISGLNRDIFSQTG 186

Query: 186 RQ--NFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATK 243
                 +QTDA+IN GN+GG L++S G L+GINT  F ++    T  G+GFAIP     K
Sbjct: 187 VTIGGGIQTDAAINPGNAGGPLLDSKGNLIGINTAIFTQTG---TSAGVGFAIPSSTVLK 243

Query: 244 IMDKLIRDGRVIRGYIGIGGREIAP------LHAQGGG-IDQLQGIVVNE---VSPDGPA 293
           I+ +LI+  +V+R  I I   E+AP      L+ + G  + Q+ G  + E   + P    
Sbjct: 244 IVPQLIQFSKVLRAGINI---ELAPDPVANQLNVRNGALVLQVPGKSLAEKAGLHPTSRG 300

Query: 294 ANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQE 350
               I + D+I++VD+KP  +  E M  + E   G  + + + R ++ L L+++++E
Sbjct: 301 FAGNIVLGDIIVAVDDKPVKNKAELMKILDEYSVGDKVTLKIKRGNEDLELKISLEE 357


>1L1J-A nrPDB
          Length = 239

 Score =  129 bits (323), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 74/193 (38%), Positives = 109/193 (56%), Gaps = 8/193 (4%)

Query: 73  QLEIRTLGSGVIMDQRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKI 132
           + ++ +LGSG I D  GYI+TN HV+  AD I V + DG  ++A  +G D   D+AV+KI
Sbjct: 51  ERQVASLGSGFIFDPEGYILTNYHVVGGADNITVTMLDGSKYDAEYIGGDEELDIAVIKI 110

Query: 133 NAT-GGLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNF-- 189
            A+    P +         IG+  +AIGNP     T+T G++SAT R    P G   +  
Sbjct: 111 KASDKKFPYLEFGDSDKVKIGEWAIAIGNPLGFQHTVTVGVVSATNRRIPKPDGSGYYVG 170

Query: 190 -LQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKL 248
            +QTDA+IN GNSGG L+N  GE++GINT   +     +    +GFAIP     K +D +
Sbjct: 171 LIQTDAAINPGNSGGPLLNIHGEVIGINTAIVNP----QEAVNLGFAIPINTVKKFLDTI 226

Query: 249 IRDGRVIRGYIGI 261
           +   +V + Y+G+
Sbjct: 227 LTQKKVEKAYLGV 239


>2Z9I-A nrPDB
          Length = 324

 Score =  117 bits (292), Expect = 9e-27,   Method: Compositional matrix adjust.
 Identities = 86/237 (36%), Positives = 119/237 (50%), Gaps = 27/237 (11%)

Query: 44  PASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDA-- 101
           P S      +  P+VV      L T+   Q E    GSG+I+   G I+TN HVI  A  
Sbjct: 5   PGSVEQVAAKVVPSVVM-----LETDLGRQSE---EGSGIILSAEGLILTNNHVIAAAAK 56

Query: 102 -------DQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDV 154
                   +  V   DGR     +VG+D  +D+AV+++    GL  I + +     +G  
Sbjct: 57  PPLGSPPPKTTVTFSDGRTAPFTVVGADPTSDIAVVRVQGVSGLTPISLGSSSDLRVGQP 116

Query: 155 VLAIGNPYNLGQTITQGIISATGR--IGLNPTGRQN----FLQTDASINHGNSGGALVNS 208
           VLAIG+P  L  T+T GI+SA  R        G QN     +QTDA+IN GNSGGALVN 
Sbjct: 117 VLAIGSPLGLEGTVTTGIVSALNRPVSTTGEAGNQNTVLDAIQTDAAINPGNSGGALVNM 176

Query: 209 LGELMGIN----TLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGI 261
             +L+G+N    TL  D ++      G+GFAIP   A +I D+LI  G+     +G+
Sbjct: 177 NAQLVGVNSAIATLGADSADAQSGSIGLGFAIPVDQAKRIADELISTGKASHASLGV 233


>3TJO-A nrPDB
          Length = 231

 Score =  114 bits (285), Expect = 7e-26,   Method: Compositional matrix adjust.
 Identities = 75/206 (36%), Positives = 115/206 (55%), Gaps = 15/206 (7%)

Query: 46  SYNL---AVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDAD 102
            YN     V + APAVV++        S  ++ + + GSG I+ + G I+TN HV+ +  
Sbjct: 29  KYNFIADVVEKIAPAVVHIELFRKLPFSKREVPVAS-GSGFIVSEDGLIVTNAHVVTNKH 87

Query: 103 QIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGNPY 162
           ++ V L++G  +EA +   D   D+A++KI+  G LP + +        G+ V+AIG+P+
Sbjct: 88  RVKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRPGEFVVAIGSPF 147

Query: 163 NLGQTITQGIISATGRIGLNPTGRQ---NFLQTDASINHGNSGGALVNSLGELMGINTLS 219
           +L  T+T GI+S T R G     R    +++QTDA IN+GN+GG LVN  GE++GINTL 
Sbjct: 148 SLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNAGGPLVNLDGEVIGINTL- 206

Query: 220 FDKSNDGETPEGIGFAIPFQLATKIM 245
                  +   GI FAIP     K +
Sbjct: 207 -------KVTAGISFAIPSDKIKKFL 225


>5M3O-A nrPDB
          Length = 334

 Score =  113 bits (282), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 101/323 (31%), Positives = 165/323 (51%), Gaps = 34/323 (10%)

Query: 45  ASYNL---AVRRAAPAVVNVYNRGLNTNSHNQLEIR-TLGSGVIMDQRGYIITNKHVIND 100
           + YN     V + APAVV  Y   L+ +     E+  + GSG ++   G I+TN HV+ D
Sbjct: 13  SQYNFIADVVEKTAPAVV--YIEILDRHPFLGREVPISNGSGFVVAADGLIVTNAHVVAD 70

Query: 101 ADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGN 160
             ++ V L  G  +EA++   D + D+A L+I     LPT+P+        G+ V+A+G+
Sbjct: 71  RRRVRVRLLSGDTYEAVVTAVDPVADIATLRIQTKEPLPTLPLGRSADVRQGEFVVAMGS 130

Query: 161 PYNLGQTITQGIISATGR----IGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGIN 216
           P+ L  TIT GI+S+  R    +GL P     ++QTDA+I+ GNSGG LVN  GE++G+N
Sbjct: 131 PFALQNTITSGIVSSAQRPARDLGL-PQTNVEYIQTDAAIDFGNSGGPLVNLDGEVIGVN 189

Query: 217 TLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVI------RGYIGIGGREIAP-- 268
           T+        +   GI FAIP     + + +  +           R YIG+    ++P  
Sbjct: 190 TM--------KVTAGISFAIPSDRLREFLHRGEKKNSSSGISGSQRRYIGVMMLTLSPSI 241

Query: 269 ---LHAQGGGIDQLQ-GIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAE 324
              L  +      +Q G+++++V    PA  AG++  D+I+++  +   +A +  + V  
Sbjct: 242 LAELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEQMVQNAEDVYEAV-- 299

Query: 325 IRPGSVIPVVVMRDDKQLTLQVT 347
            R  S + V + R  + LTL VT
Sbjct: 300 -RTQSQLAVQIRRGRETLTLYVT 321


>4IC5-A nrPDB
          Length = 291

 Score =  100 bits (250), Expect = 7e-22,   Method: Compositional matrix adjust.
 Identities = 70/196 (35%), Positives = 97/196 (49%), Gaps = 15/196 (7%)

Query: 75  EIRTLGSGVIMDQRGYIITNKHVINDADQIIVALQDGRVF-----------EALLVGSDS 123
           +I   GSG + D+ G+I+TN HVI         LQ  +V            E  +VG D 
Sbjct: 77  KIEGTGSGFVWDKLGHIVTNYHVIAKLATDQFGLQRCKVSLVDAKGTRFSKEGKIVGLDP 136

Query: 124 LTDLAVLKINATG-GLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLN 182
             DLAVLKI   G  L  + +       +G    AIGNPY    T+T G++S  GR   +
Sbjct: 137 DNDLAVLKIETEGRELNPVVLGTSNDLRVGQSCFAIGNPYGYENTLTIGVVSGLGREIPS 196

Query: 183 PTGRQ--NFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQL 240
           P G+     +QTDA IN GN+GG L++S G  +G+NT +F +   G +  G+ FAIP   
Sbjct: 197 PNGKSISEAIQTDADINSGNAGGPLLDSYGHTIGVNTATFTRKGSGMS-SGVNFAIPIDT 255

Query: 241 ATKIMDKLIRDGRVIR 256
             + +  LI  G   R
Sbjct: 256 VVRTVPYLIVYGTAYR 271


>5ILB-A nrPDB
          Length = 474

 Score = 64.7 bits (156), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 70/266 (26%), Positives = 121/266 (45%), Gaps = 23/266 (8%)

Query: 57  AVVNVYNRGLNTN----SHNQLEIRTLGSGVIMDQRGYIITNKHVINDADQIIVALQ-DG 111
           AVV VY      +       Q +  + GS  ++   G ++TN H +    Q+ V  + D 
Sbjct: 9   AVVKVYCTHTAPDYSLPWQKQRQFTSTGSAFMIGD-GKLLTNAHCVEHDTQVKVKRRGDD 67

Query: 112 RVFEALLVGSDSLTDLAVLKINATGGLP-TIPINARRVPHIGDVVLAIGNPYNLGQTI-- 168
           R + A ++      D+A+L + +        P+    +P + D V  +G P   G TI  
Sbjct: 68  RKYVAKVLVRGVDCDIALLSVESEDFWKGAEPLRLGHLPRLQDSVTVVGYPLG-GDTISV 126

Query: 169 TQGIISATGRIGLNPTGRQNFL--QTDASINHGNSGGALVNSLGELMGINTLSFDKSNDG 226
           T+G++S    +     G  + L  Q DA+IN GNSGG   N  GE +G+   +F      
Sbjct: 127 TKGVVSRI-EVTSYAHGSSDLLGIQIDAAINPGNSGGPAFNDQGECIGV---AFQVYRSE 182

Query: 227 ETPEGIGFAIPFQLATKIMDKLIRDGRVIRGY--IGIGGREIA--PLHAQGGGIDQLQGI 282
           ET E IG+ IP  + +  +    R+G+   G+  +GI  +++    L    G     +G+
Sbjct: 183 ET-ENIGYVIPTTVVSHFLTDYERNGKYT-GFPVLGIEWQKMENPDLRKSMGMESHQKGV 240

Query: 283 VVNEVSPDGPAANAGIQVNDLIISVD 308
            +  + P  P +   ++ +D+I+S D
Sbjct: 241 RIRRIEPTAPESQV-LKPSDIILSFD 265


>4FLN-A nrPDB
          Length = 539

 Score = 64.3 bits (155), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 71/266 (26%), Positives = 120/266 (45%), Gaps = 22/266 (8%)

Query: 57  AVVNVYNRGLNTN----SHNQLEIRTLGSGVIMDQRGYIITNKHVINDADQIIVALQ-DG 111
           AVV VY      +       Q +  + GS  ++   G ++TN H +    Q+ V  + D 
Sbjct: 49  AVVKVYCTHTAPDYSLPWQKQRQFTSTGSAFMIGD-GKLLTNAHCVEHDTQVKVKRRGDD 107

Query: 112 RVFEALLVGSDSLTDLAVLKINATGGLP-TIPINARRVPHIGDVVLAIGNPYNLGQTI-- 168
           R + A ++      D+A+L + +        P+    +P + D V  +G P   G TI  
Sbjct: 108 RKYVAKVLVRGVDCDIALLSVESEDFWKGAEPLRLGHLPRLQDSVTVVGYPLG-GDTISV 166

Query: 169 TQGIISATGRIGLNPTGRQNFL--QTDASINHGNSGGALVNSLGELMGINTLSFDKSNDG 226
           T+G++S    +     G  + L  Q DA+IN GNSGG   N  GE +G+   +F      
Sbjct: 167 TKGVVSRI-EVTSYAHGSSDLLGIQIDAAINPGNSGGPAFNDQGECIGV---AFQVYRSE 222

Query: 227 ETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIG---GREIAPLHAQGGGIDQLQGIV 283
           ET E IG+ IP  + +  +    R+G+   GY  +G    +   P   +   +   +G++
Sbjct: 223 ET-ENIGYVIPTTVVSHFLTDYERNGKYT-GYPCLGVLLQKLENPALRECLKVPTNEGVL 280

Query: 284 VNEVSPDGPAANAGIQVNDLIISVDN 309
           V  V P   A+   ++  D+I+S D+
Sbjct: 281 VRRVEPTSDASKV-LKEGDVIVSFDD 305


>5HM9-A nrPDB
          Length = 189

 Score = 52.4 bits (124), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 48/164 (29%), Positives = 77/164 (46%), Gaps = 9/164 (5%)

Query: 81  SGVIMDQRGYIITNKHVINDADQIIVALQDG---RVFEALLVGSDSLTDLAVLKINATGG 137
           SG I+   GY+IT  H ++   +I V +      R F A +V +    DLA+LK+  T  
Sbjct: 24  SGAIVGTNGYVITTLHSVSKLPEISVQVATTGGIRRFPAQVVKTIPGHDLALLKMQTTEK 83

Query: 138 LPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGII-SATGRIGLNPTGRQNFLQTDASI 196
                +   +    G  V A G        + QG++ SA   + +  T   + L++DA  
Sbjct: 84  FLHFRMADVQTVVPGQQVFAFGRNMAGAPLVRQGLVQSADAPLAVGATQITHLLRSDAVY 143

Query: 197 NHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQL 240
           +   +GG LVN+ G+L+GIN      +  G T +  GF +P Q+
Sbjct: 144 SWEQTGGPLVNAQGDLVGINI-----AATGPTGKVEGFTVPAQV 182


>5JYK-A nrPDB
          Length = 566

 Score = 51.6 bits (122), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 63/242 (26%), Positives = 104/242 (42%), Gaps = 27/242 (11%)

Query: 81  SGVIMDQRGYIITNKHVINDADQIIVALQ--DGRVFEALL-VGSDSLTDLAVLKINATGG 137
           SG I+  R  ++TN H +    Q+ +  +  D +    +L +G++   D+A+L +     
Sbjct: 129 SGFIIGGR-RVLTNAHSVEHHTQVKLKKRGSDTKYLATVLAIGTE--CDIALLTVTDDEF 185

Query: 138 LPTI-PINARRVPHIGDVVLAIGNPYNLGQTI--TQGIISATGRIGLNPTGRQNF-LQTD 193
              + P+    +P + D V  +G P   G TI  T G++S    +       +   LQ D
Sbjct: 186 WEGVSPVEFGDLPALQDAVTVVGYPIG-GDTISVTSGVVSRMEILSYVHGSTELLGLQID 244

Query: 194 ASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGR 253
           A+IN GNSGG   N  G+ +GI   S       E  E IG+ IP    T ++   I+D  
Sbjct: 245 AAINSGNSGGPAFNDKGKCVGIAFQSLKH----EDAENIGYVIP----TPVIVHFIQDYE 296

Query: 254 VIRGYIGI-------GGREIAPLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIIS 306
               Y G           E   L    G     +G+ +  + P  P +   ++ +D+I+S
Sbjct: 297 KHDKYTGFPVLGIEWQKMENPDLRKSMGMESHQKGVRIRRIEPTAPESQV-LKPSDIILS 355

Query: 307 VD 308
            D
Sbjct: 356 FD 357


>5ILA-A nrPDB
          Length = 301

 Score = 45.1 bits (105), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 51/178 (28%), Positives = 82/178 (46%), Gaps = 19/178 (10%)

Query: 81  SGVIMDQRGYIITNKHVINDADQIIVALQ--DGRVFEALL-VGSDSLTDLAVLKINATGG 137
           SG I+  R  ++TN H +    Q+ +  +  D +    +L +G++   D+A+L +     
Sbjct: 129 SGFIIGGR-RVLTNAHSVEHHTQVKLKKRGSDTKYLATVLAIGTE--CDIALLTVTDDEF 185

Query: 138 LPTI-PINARRVPHIGDVVLAIGNPYNLGQTI--TQGIISATGRIGLNPTGRQNF-LQTD 193
              + P+    +P + D V  +G P   G TI  T G++S    +       +   LQ D
Sbjct: 186 WEGVSPVEFGDLPALQDAVTVVGYPIG-GDTISVTSGVVSRMEILSYVHGSTELLGLQID 244

Query: 194 ASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRD 251
           A+IN GNSGG   N  G+ +GI   S       E  E IG+ IP    T ++   I+D
Sbjct: 245 AAINSGNSGGPAFNDKGKCVGIAFQSLKH----EDAENIGYVIP----TPVIVHFIQD 294


>4FGM-A nrPDB
          Length = 597

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 25/77 (32%), Positives = 43/77 (55%), Gaps = 4/77 (5%)

Query: 280 QGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIR-PGSVIPVVVMRD 338
           QG+ V  V  D  A +AG+   D II++D+  A    +++ ++ E   PG  + +   R 
Sbjct: 496 QGLDVLNVYHDESAYHAGLSAGDKIIAIDHLQATE--QSVKRILERYIPGDTVTIHAFRR 553

Query: 339 DKQLTLQVTIQEYPATN 355
           D+ +TL++T QE PA +
Sbjct: 554 DELMTLELTWQE-PAKS 569


>2KJP-A nrPDB
          Length = 91

 Score = 37.4 bits (85), Expect = 0.010,   Method: Composition-based stats.
 Identities = 21/72 (29%), Positives = 41/72 (56%), Gaps = 1/72 (1%)

Query: 281 GIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDDK 340
           GI  + V  + PA    I+V D IIS D K   SA + +D ++  + G  + + + R++K
Sbjct: 2   GIYASSVVENMPA-KGKIEVGDKIISADGKNYQSAEKLIDYISSKKAGDKVTLKIEREEK 60

Query: 341 QLTLQVTIQEYP 352
           +  + +T++++P
Sbjct: 61  EKRVTLTLKQFP 72


>5C2Z-A nrPDB
          Length = 255

 Score = 33.9 bits (76), Expect = 0.11,   Method: Compositional matrix adjust.
 Identities = 45/169 (26%), Positives = 76/169 (44%), Gaps = 39/169 (23%)

Query: 77  RTLGSGVIMDQRGYIITNKHVI----NDADQIIVALQDGRVFEALLVG-------SDSL- 124
           +T+ +G+++  +  +ITNKH+     ND +++I      R   +L+V        ++ + 
Sbjct: 54  KTIATGILIG-KNTVITNKHIARLAENDPNKVIFTPGSTRDEGSLVVKKPFGEFIAEEIN 112

Query: 125 -------TDLAVLKIN------ATGGLPT---IPINARRVPHIGDVVLAIGNPYNLGQTI 168
                  TDL+++K+       + G L T   IP N       GD +  +G PYN   T 
Sbjct: 113 EAPYGGGTDLSIIKLKPNQYGKSAGDLVTPAAIPDNVDV--QKGDKISLLGYPYN---TS 167

Query: 169 TQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINT 217
           T  +  +   +  N T      Q  A    GNSG  + N  GEL+GI++
Sbjct: 168 THSLYKSQIEVFNNQT-----FQYFAYTEPGNSGSGIFNLHGELVGIHS 211


>2VZ5-A nrPDB
          Length = 139

 Score = 33.5 bits (75), Expect = 0.15,   Method: Compositional matrix adjust.
 Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 17/91 (18%)

Query: 273 GGGIDQL------------QGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMD 320
           GGGIDQ             +GI V  VS  GPA  AG+Q+ D I+ V+       + T D
Sbjct: 45  GGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDM--TMVTHD 102

Query: 321 QVAE---IRPGSVIPVVVMRDDKQLTLQVTI 348
           Q  +    R   V+ ++V R   Q  +Q ++
Sbjct: 103 QARKRLTKRSEEVVRLLVTRQSLQKAVQQSM 133


>3LT3-A nrPDB
          Length = 217

 Score = 33.1 bits (74), Expect = 0.20,   Method: Compositional matrix adjust.
 Identities = 45/174 (25%), Positives = 76/174 (43%), Gaps = 16/174 (9%)

Query: 48  NLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDADQIIVA 107
           N  V    P+VV +  R L       LE    G+G ++     ++TN HV+  ++ + V 
Sbjct: 14  NPVVAATEPSVVKI--RSLAPRCQKVLE----GTGFVISPD-RVMTNAHVVAGSNNVTVY 66

Query: 108 LQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGNPYNLGQT 167
             D + FEA +V  D   D+A+L +      P +   A      G  V+ +G P     T
Sbjct: 67  AGD-KPFEATVVSYDPSVDVAILAVPHLPPPPLV--FAAEPAKTGADVVVLGYPGGGNFT 123

Query: 168 ITQGIISATGRI-GLNPTGRQNFLQTD-----ASINHGNSGGALVNSLGELMGI 215
            T   I    R+ G +  G    +  D     A +  G++GG L++  G+++G+
Sbjct: 124 ATPARIREAIRLSGPDIYGDPEPVTRDVYTIRADVEQGDAGGPLIDLNGQVLGV 177


>2L4S-A nrPDB
          Length = 124

 Score = 32.7 bits (73), Expect = 0.27,   Method: Compositional matrix adjust.
 Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 17/91 (18%)

Query: 273 GGGIDQL------------QGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMD 320
           GGGIDQ             +GI V  VS  GPA  AG+Q+ D I+ V+       + T D
Sbjct: 34  GGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDM--TMVTHD 91

Query: 321 QVAE---IRPGSVIPVVVMRDDKQLTLQVTI 348
           Q  +    R   V+ ++V R   Q  +Q ++
Sbjct: 92  QARKRLTKRSEEVVRLLVTRQSLQKAVQQSM 122


>1VRA-B nrPDB
          Length = 215

 Score = 32.3 bits (72), Expect = 0.33,   Method: Compositional matrix adjust.
 Identities = 31/118 (26%), Positives = 47/118 (39%), Gaps = 26/118 (22%)

Query: 188 NFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDG-----------------ETPE 230
           +F+ TDA+I+HG+  GAL     E     T+  D S +                  E P+
Sbjct: 4   SFVTTDANIDHGHLQGALSAITNETFNRITVDGDTSTNDMVVVMASGLAENETLTPEHPD 63

Query: 231 GIGFAIPFQLATKIMDKLI-RDGRVIRGYIGIGGREIAPLHAQGGGIDQLQGIVVNEV 287
              F    QLA + + K I RDG         G  ++  +   G   DQ  G+V  ++
Sbjct: 64  WANFYKALQLACEDLAKQIARDGE--------GATKLIEVEVTGAANDQEAGMVAKQI 113


>4O06-A nrPDB
          Length = 106

 Score = 30.8 bits (68), Expect = 0.87,   Method: Compositional matrix adjust.
 Identities = 20/66 (30%), Positives = 36/66 (54%), Gaps = 2/66 (3%)

Query: 284 VNEVSPDGPAANAGIQVNDLIISVDNKPAI--SALETMDQVAEIRPGSVIPVVVMRDDKQ 341
           ++EV P  P+  A I+V+D +IS+ N  A   S L+ +  V        +PV+++R+ + 
Sbjct: 23  ISEVVPGSPSDKADIKVDDKLISIGNVHAANHSKLQNIQMVVMKNEDRPLPVLLLREGQI 82

Query: 342 LTLQVT 347
           L   +T
Sbjct: 83  LKTSLT 88


>5KAY-A nrPDB
          Length = 201

 Score = 30.0 bits (66), Expect = 1.5,   Method: Compositional matrix adjust.
 Identities = 14/36 (38%), Positives = 20/36 (55%)

Query: 42  ETPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIR 77
           +TP   N   +  A A ++  NRGL  + HN LE+R
Sbjct: 153 KTPVEGNNVEKEKAAAAIDKTNRGLKNSLHNVLEVR 188


>6A9U-A nrPDB
          Length = 455

 Score = 30.0 bits (66), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 9/60 (15%)

Query: 275 GIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMD--QVAEIRPGSVIP 332
           GID++ G  V ++ P     N G+ V+D+       P +S  E +   QV  I PG  IP
Sbjct: 342 GIDKVSGWNVEKLYPHYIGHNLGLDVHDV-------PKVSRYEPLKVGQVITIEPGLYIP 394


>1WCZ-A nrPDB
          Length = 268

 Score = 29.3 bits (64), Expect = 2.8,   Method: Compositional matrix adjust.
 Identities = 40/155 (25%), Positives = 66/155 (42%), Gaps = 22/155 (14%)

Query: 79  LGSGVIMDQRGYIITNKHVINDADQIIVALQDGRVFEALLVGSD----SLTDLAVLKINA 134
           + SGV++  +  ++TNKHV++       AL   + F + +   +      T   + K + 
Sbjct: 35  IASGVVVG-KDTLLTNKHVVDATHGDPHAL---KAFPSAINQDNYPNGGFTAEQITKYSG 90

Query: 135 TGGLPTIPINA-RRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNP-------TGR 186
            G L  +  +   +  HIG+VV       N    + Q I + TG  G  P        G+
Sbjct: 91  EGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNI-TVTGYPGDKPVATMWESKGK 149

Query: 187 QNFL-----QTDASINHGNSGGALVNSLGELMGIN 216
             +L     Q D S   GNSG  + N   E++GI+
Sbjct: 150 ITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIH 184


>4C2G-A nrPDB
          Length = 446

 Score = 28.9 bits (63), Expect = 3.2,   Method: Compositional matrix adjust.
 Identities = 24/72 (33%), Positives = 38/72 (52%), Gaps = 7/72 (9%)

Query: 287 VSP--DGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIR--PGSVIPVVVMR--DDK 340
           VSP    PA  AG++ ND IIS+ N  +++  +    V +IR   GS + + + R    K
Sbjct: 86  VSPFKKSPAEKAGLKPNDEIISI-NGESMAGKDLNHAVLKIRGKKGSSVSMKIQRPGTKK 144

Query: 341 QLTLQVTIQEYP 352
           QL+ ++   E P
Sbjct: 145 QLSFRIKRAEIP 156


>2AS9-A nrPDB
          Length = 210

 Score = 28.9 bits (63), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 5/73 (6%)

Query: 143 INARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSG 202
            N  +   + D +  IG P     +  Q    +TG I      + N L  DA I  GNSG
Sbjct: 105 FNFAKDAKVDDKIKVIGYPLPAQNSFKQ--FESTGTI---KRIKDNILNFDAYIEPGNSG 159

Query: 203 GALVNSLGELMGI 215
             ++NS  E++G+
Sbjct: 160 SPVLNSNNEVIGV 172


>1DT2-A nrPDB
          Length = 245

 Score = 28.5 bits (62), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 47/167 (28%), Positives = 67/167 (40%), Gaps = 39/167 (23%)

Query: 78  TLGSGVIMDQRGYIITNKHVINDADQ----IIVALQDGR------------VFEALLVGS 121
           TL +GV++  +  I+TN HV  +A +    II      R             FEA  +  
Sbjct: 47  TLATGVLIG-KNTIVTNYHVAREAAKNPSNIIFTPAQNRDAEKNEFPTPYGKFEAEEIKE 105

Query: 122 DSL---TDLAVLKI--NATGGLPTIPINARRVP-HI----GDVVLAIGNPYNL-GQTITQ 170
                  DLA++K+  N  G      I    +P HI    GD    +G PYN    ++ Q
Sbjct: 106 SPYGQGLDLAIIKLKPNEKGESAGDLIQPANIPDHIDIQKGDKYSLLGYPYNYSAYSLYQ 165

Query: 171 GIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINT 217
             I             Q F  T+     GNSG  + N  GEL+GI++
Sbjct: 166 SQIEMF-------NDSQYFGYTEV----GNSGSGIFNLKGELIGIHS 201


>2V90-A nrPDB
          Length = 96

 Score = 28.5 bits (62), Expect = 5.2,   Method: Composition-based stats.
 Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 2/63 (3%)

Query: 275 GIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIR-PGSVIPV 333
           G+D   G  + EV P  PA  AG+Q  D +++V  + ++  L   + V+ I+  GS + +
Sbjct: 25  GLDGRPGQFLWEVDPGLPAKKAGMQAGDRLVAVAGE-SVEGLGHEETVSRIQGQGSCVSL 83

Query: 334 VVM 336
            V+
Sbjct: 84  TVV 86


>5JWG-A nrPDB
          Length = 703

 Score = 28.5 bits (62), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 25/39 (64%), Gaps = 4/39 (10%)

Query: 188 NFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDG 226
           NF  T  +   GN+G  ++N+ GEL+G+N   FD++ +G
Sbjct: 620 NFCATTHTTG-GNAGSPVMNARGELIGLN---FDRNWEG 654


>2W7U-A nrPDB
          Length = 200

 Score = 28.1 bits (61), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 5/65 (7%)

Query: 151 IGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLG 210
           + D +  IG P   G      +  +TG I  + +G   F++ DA    GNSG  ++NS  
Sbjct: 109 VKDRISVIGYP--KGAQTKYKMFESTGTIN-HISG--TFMEFDAYAQPGNSGSPVLNSKH 163

Query: 211 ELMGI 215
           EL+GI
Sbjct: 164 ELIGI 168


>5MM8-A nrPDB
          Length = 204

 Score = 28.1 bits (61), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 13/31 (41%), Positives = 21/31 (67%)

Query: 186 RQNFLQTDASINHGNSGGALVNSLGELMGIN 216
           + N + TDA +  GNSG A+ NS  E++G++
Sbjct: 142 KGNMIITDAFVEPGNSGSAVFNSKYEVVGVH 172


>3WYB-A nrPDB
          Length = 334

 Score = 28.1 bits (61), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 24/90 (26%), Positives = 44/90 (48%), Gaps = 7/90 (7%)

Query: 114 FEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGNPYNL-GQTITQGI 172
           F+A+   ++    +A++ +    GL ++     R+  +G+VVL +GN Y   G+ ++QG 
Sbjct: 103 FDAVNAAAEQSGKVAIISVGWDPGLFSL----NRL--LGEVVLPVGNTYTFWGKGVSQGH 156

Query: 173 ISATGRIGLNPTGRQNFLQTDASINHGNSG 202
             A  RI       Q  +  D ++N   SG
Sbjct: 157 SDAIRRIQGVKNAVQYTIPIDEAVNRVRSG 186


>4K1S-A nrPDB
          Length = 206

 Score = 28.1 bits (61), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 16/41 (39%), Positives = 23/41 (56%)

Query: 194 ASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGF 234
           A    GNSG  ++NS  EL+GI+  S  K++D     G+ F
Sbjct: 152 AHTESGNSGSPVLNSNNELVGIHFASDVKNDDNRNAYGVYF 192


>4XZY-A nrPDB
          Length = 720

 Score = 28.1 bits (61), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 13/28 (46%), Positives = 21/28 (75%), Gaps = 3/28 (10%)

Query: 199 GNSGGALVNSLGELMGINTLSFDKSNDG 226
           GNSG  ++N+ GEL+G+N   FD++ +G
Sbjct: 653 GNSGSPVMNANGELIGLN---FDRNWEG 677


>4DLL-A nrPDB
          Length = 320

 Score = 28.1 bits (61), Expect = 6.4,   Method: Compositional matrix adjust.
 Identities = 16/38 (42%), Positives = 22/38 (57%)

Query: 101 ADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGL 138
           A+Q+IV +  G V EALL  +    D+A +K   TGG 
Sbjct: 201 ANQMIVGITIGAVAEALLFATKGGADMAKVKEAITGGF 238


>1FC9-A nrPDB
          Length = 388

 Score = 27.7 bits (60), Expect = 7.3,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 1/39 (2%)

Query: 282 IVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMD 320
           +VV   +P GPA  AG +  D+I++VD   A+  L   D
Sbjct: 101 VVVLTPAPGGPAEKAGARAGDVIVTVDGT-AVKGLSLYD 138


>3EGH-C nrPDB
          Length = 170

 Score = 27.3 bits (59), Expect = 9.7,   Method: Compositional matrix adjust.
 Identities = 17/35 (48%), Positives = 23/35 (65%), Gaps = 2/35 (5%)

Query: 275 GIDQLQGIVVNEVSPDGPAANAG-IQVNDLIISVD 308
           G+++L GI V  V+  G A   G IQVNDL++ VD
Sbjct: 107 GLEKL-GIFVKTVTEGGAAHRDGRIQVNDLLVEVD 140


>5ZDS-A nrPDB
          Length = 96

 Score = 27.3 bits (59), Expect = 9.9,   Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 9/54 (16%)

Query: 281 GIVVNEVSPDGPAANAG-IQVNDLIISVD--------NKPAISALETMDQVAEI 325
           GI V  + P GPAA  G I   D ++ VD        +K A+  L+   QVA +
Sbjct: 37  GIYVKSIIPGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQCLKGPGQVARL 90


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

3GCO-A nrPDB                                                          429   e-120
5JD8-A nrPDB                                                          356   9e-99
5Y2D-A nrPDB                                                          342   1e-94
5Y28-A nrPDB                                                          333   5e-92
3STJ-A nrPDB                                                          327   4e-90
3MH6-A nrPDB                                                          326   8e-90
4A8B-A nrPDB                                                          326   8e-90
4YNN-A nrPDB                                                          316   1e-86
2QF3-A nrPDB                                                          316   1e-86
3PV2-A nrPDB                                                          314   3e-86
3PV4-A nrPDB                                                          310   6e-85
4YO1-A nrPDB                                                          309   9e-85
3QO6-A nrPDB                                                          303   7e-83
3NUM-A nrPDB                                                          299   1e-81
4RI0-A nrPDB                                                          293   7e-80
5T69-A nrPDB                                                          291   3e-79
2R3U-A nrPDB                                                          281   2e-76
5M3O-A nrPDB                                                          273   8e-74
4FLN-A nrPDB                                                          270   7e-73
5ILB-A nrPDB                                                          269   1e-72
4IC6-A nrPDB                                                          268   3e-72
6IEO-A nrPDB                                                          257   6e-69
5JYK-A nrPDB                                                          243   7e-65
1L1J-A nrPDB                                                          235   2e-62
3STI-A nrPDB                                                          234   4e-62
3TJO-A nrPDB                                                          232   1e-61
2Z9I-A nrPDB                                                          216   2e-56
4IC5-A nrPDB                                                          206   9e-54
5ILA-A nrPDB                                                          186   2e-47
5HM9-A nrPDB                                                          158   4e-39

Sequences not found previously or not previously below threshold:

3LT3-A nrPDB                                                           73   1e-13
1DUE-A nrPDB                                                           60   2e-09
4INK-A nrPDB                                                           59   3e-09
2KL1-A nrPDB                                                           57   1e-08
5MM8-A nrPDB                                                           56   3e-08
2AS9-A nrPDB                                                           54   1e-07
4JCN-A nrPDB                                                           52   3e-07
2KJP-A nrPDB                                                           51   7e-07
4JJ3-A nrPDB                                                           50   1e-06
1DT2-A nrPDB                                                           50   2e-06
4QL6-A nrPDB                                                           49   3e-06
2W7U-A nrPDB                                                           49   4e-06
1WCZ-A nrPDB                                                           48   6e-06
3I1E-A nrPDB                                                           48   6e-06
2KJK-A nrPDB                                                           48   7e-06
4K1S-A nrPDB                                                           47   9e-06
5C2Z-A nrPDB                                                           46   2e-05
3I18-A nrPDB                                                           45   6e-05
4FGM-A nrPDB                                                           44   1e-04
5E6P-B nrPDB                                                           44   1e-04
2DLS-A nrPDB                                                           43   2e-04
4C2G-A nrPDB                                                           42   3e-04
4O06-A nrPDB                                                           42   3e-04
2XKX-A nrPDB                                                           42   6e-04
2EAQ-A nrPDB                                                           41   6e-04
2PKT-A nrPDB                                                           41   7e-04
2HLC-A nrPDB                                                           40   0.001
1UEZ-A nrPDB                                                           40   0.002
1FC9-A nrPDB                                                           39   0.003
2V90-A nrPDB                                                           39   0.003
2L4S-A nrPDB                                                           39   0.004
2VZ5-A nrPDB                                                           38   0.006
2QBW-A nrPDB                                                           38   0.007
3K1R-A nrPDB                                                           38   0.007
3CH8-A nrPDB                                                           38   0.007
3TSW-A nrPDB                                                           37   0.009
3SHW-A nrPDB                                                           37   0.009
1MFG-A nrPDB                                                           37   0.012
1M5Z-A nrPDB                                                           37   0.014
3CYY-A nrPDB                                                           37   0.015
4Q2Q-A nrPDB                                                           37   0.015
5G1D-A nrPDB                                                           37   0.015
2KBS-A nrPDB                                                           37   0.017
5N7D-A nrPDB                                                           37   0.017
5A2P-A nrPDB                                                           37   0.018
1X5N-A nrPDB                                                           36   0.020
5ZDS-A nrPDB                                                           36   0.022
3TSV-A nrPDB                                                           36   0.024
1UEQ-A nrPDB                                                           36   0.028
1UF1-A nrPDB                                                           35   0.035
4XZY-A nrPDB                                                           35   0.038
3SHU-A nrPDB                                                           35   0.043
1NPM-A nrPDB                                                           35   0.045
3BPU-A nrPDB                                                           35   0.051
2LOB-A nrPDB                                                           35   0.059
5JXF-A nrPDB                                                           34   0.073
5JWG-A nrPDB                                                           34   0.078
3K50-A nrPDB                                                           34   0.079
2RCZ-A nrPDB                                                           34   0.085
2DC2-A nrPDB                                                           34   0.11 
2R4H-A nrPDB                                                           34   0.11 
3WOM-A nrPDB                                                           34   0.11 
4JOF-A nrPDB                                                           34   0.12 
3G8Q-A nrPDB                                                           34   0.13 
3SOE-A nrPDB                                                           34   0.14 
5HJ1-A nrPDB                                                           34   0.15 
2LC7-A nrPDB                                                           34   0.16 
3H7F-A nrPDB                                                           33   0.18 
1RY4-A nrPDB                                                           33   0.19 
3QDO-A nrPDB                                                           33   0.19 
2QT5-A nrPDB                                                           33   0.20 
3WYB-A nrPDB                                                           33   0.23 
2D8I-A nrPDB                                                           33   0.23 
1NF3-C nrPDB                                                           32   0.31 
1UJV-A nrPDB                                                           32   0.31 
2JIL-A nrPDB                                                           32   0.34 
1WFV-A nrPDB                                                           32   0.34 
6FAH-A nrPDB                                                           32   0.47 
4NXP-A nrPDB                                                           32   0.50 
1U3B-A nrPDB                                                           31   0.68 
1X5R-A nrPDB                                                           31   0.74 
2I6V-A nrPDB                                                           31   0.79 
2WV5-A nrPDB                                                           31   0.84 
1CT4-E nrPDB                                                           31   0.88 
2I4S-A nrPDB                                                           31   0.97 
2SGA-A nrPDB                                                           31   1.0  
1PQ7-A nrPDB                                                           30   1.1  
3SUZ-A nrPDB                                                           30   1.1  
1U37-A nrPDB                                                           30   1.2  
1ZZM-A nrPDB                                                           30   1.5  
4OEP-A nrPDB                                                           30   1.8  
2SFA-A nrPDB                                                           30   1.8  
1Y7N-A nrPDB                                                           30   1.9  
5MV8-B nrPDB                                                           30   2.1  
3EGH-C nrPDB                                                           30   2.1  
1UEW-A nrPDB                                                           30   2.3  
2WV9-A nrPDB                                                           29   2.5  
1V6B-A nrPDB                                                           29   2.5  
3GX9-A nrPDB                                                           29   3.0  
2WZQ-A nrPDB                                                           29   3.4  
1YJS-A nrPDB                                                           29   3.7  
1U39-A nrPDB                                                           29   4.4  
1AZZ-A nrPDB                                                           29   4.5  
1GBE-A nrPDB                                                           29   5.1  
3NK6-A nrPDB                                                           28   5.4  
1V62-A nrPDB                                                           28   5.9  
6N4D-A nrPDB                                                           28   6.9  
3BSF-A nrPDB                                                           28   7.5  
1P3E-A nrPDB                                                           28   8.6  

>3GCO-A nrPDB
          Length = 340

 Score =  429 bits (1103), Expect = e-120,   Method: Composition-based stats.
 Identities = 327/329 (99%), Positives = 327/329 (99%)

Query: 27  RSLNPLSTPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMD 86
           RSLNPLSTPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMD
Sbjct: 12  RSLNPLSTPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMD 71

Query: 87  QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINAR 146
           QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINAR
Sbjct: 72  QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINAR 131

Query: 147 RVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALV 206
           RVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASIN GNSGGALV
Sbjct: 132 RVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINPGNSGGALV 191

Query: 207 NSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREI 266
           NSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREI
Sbjct: 192 NSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREI 251

Query: 267 APLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIR 326
           APLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETM QVAEIR
Sbjct: 252 APLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMAQVAEIR 311

Query: 327 PGSVIPVVVMRDDKQLTLQVTIQEYPATN 355
           PGSVIPVVVMRDDKQLTLQVTIQEYPATN
Sbjct: 312 PGSVIPVVVMRDDKQLTLQVTIQEYPATN 340


>5JD8-A nrPDB
          Length = 334

 Score =  356 bits (913), Expect = 9e-99,   Method: Composition-based stats.
 Identities = 229/310 (73%), Positives = 266/310 (85%), Gaps = 2/310 (0%)

Query: 41  DETPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVIND 100
           +E P SYN AVRRAAPAVVNVYNR L+  +   L IRTLGSGVIM  +GYI+TNKHVIND
Sbjct: 14  EEVPTSYNQAVRRAAPAVVNVYNRSLSA-TQQGLAIRTLGSGVIMSDKGYILTNKHVIND 72

Query: 101 ADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGN 160
           A+QIIVA+Q+GR+ EALLVGSD+LTDLAVLKI+AT  LP IPIN  R PHIGDVVLAIGN
Sbjct: 73  AEQIIVAMQNGRISEALLVGSDNLTDLAVLKIDATN-LPVIPININRTPHIGDVVLAIGN 131

Query: 161 PYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTLSF 220
           PYNLGQT+TQGIISATGRIGL+ +GRQNFLQTDASIN GNSGGALVN+LGELMGINTLSF
Sbjct: 132 PYNLGQTVTQGIISATGRIGLSSSGRQNFLQTDASINQGNSGGALVNTLGELMGINTLSF 191

Query: 221 DKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREIAPLHAQGGGIDQLQ 280
           DKSN+GETPEGIGFAIP  LATK+M+KLIRDGRVIRGYIGI G E  P +A   G D++ 
Sbjct: 192 DKSNNGETPEGIGFAIPTALATKVMEKLIRDGRVIRGYIGITGEEYPPFNANDNGSDRVH 251

Query: 281 GIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDDK 340
           GI V +VSPDGPAA AGI V D+I++V+NKPA S +ETMDQVAE+RPG+ IPV+++R+ +
Sbjct: 252 GIKVKKVSPDGPAAQAGIHVGDIILNVNNKPATSVIETMDQVAEVRPGTTIPVLLLRNGQ 311

Query: 341 QLTLQVTIQE 350
           Q+ +Q+TI E
Sbjct: 312 QIAVQITITE 321


>5Y2D-A nrPDB
          Length = 465

 Score =  342 bits (877), Expect = 1e-94,   Method: Composition-based stats.
 Identities = 131/364 (35%), Positives = 198/364 (54%), Gaps = 35/364 (9%)

Query: 16  GAILLVAMPSLRSLNPLSTPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTNSH---- 71
           G I + +MP ++    +S P   S D+T  SY+ +++ +  AVVN+       N+     
Sbjct: 8   GNIQIQSMPKVKER--VSVP---SKDDTIYSYHDSIKDSIKAVVNISTEKKIKNNFIGGG 62

Query: 72  -------------------NQLEIRTLGSGVIMDQRGYIITNKHVINDADQIIVALQ-DG 111
                               +   R LGSGVI+ + GYI+TN HVI+ AD+I V +    
Sbjct: 63  VFNDPFFQQFFGDLGGMIPKERMERALGSGVIISKDGYIVTNNHVIDGADKIKVTIPGSN 122

Query: 112 RVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQG 171
           + + A LVG+DS +DLAV++I     LPTI  +      +GD+V AIGNP+ +G+++TQG
Sbjct: 123 KEYSATLVGTDSESDLAVIRI-TKDNLPTIKFSDSNDISVGDLVFAIGNPFGVGESVTQG 181

Query: 172 IISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEG 231
           I+SA  + G+     +NF+QTDASIN GNSGGAL++S G L+GINT    K+       G
Sbjct: 182 IVSALNKSGIGINSYENFIQTDASINPGNSGGALIDSRGGLVGINTAIISKTGGN---HG 238

Query: 232 IGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREIAPLHAQGGGIDQLQGIVVNEVSPDG 291
           IGFAIP  +    + +LI+ G++ RGY+G+G ++++         D  +G VV  V  D 
Sbjct: 239 IGFAIPSNMVKDTVTQLIKTGKIERGYLGVGLQDLSGDLQN--SYDNKEGAVVISVEKDS 296

Query: 292 PAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQEY 351
           PA  AGI V DLI  V+ K   +  E  + +  + P   + + V+RD K+    +T+ E 
Sbjct: 297 PAKKAGILVWDLITEVNGKKVKNTNELRNLIGSMLPNQRVTLKVIRDKKERAFTLTLAER 356

Query: 352 PATN 355
              N
Sbjct: 357 KNPN 360



 Score = 46.6 bits (109), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 12/68 (17%), Positives = 33/68 (48%), Gaps = 1/68 (1%)

Query: 260 GIGGREIAPLHAQGGGI-DQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALET 318
           G+   ++     +   + D +QG++V++V+ + PA  AG +  ++I  ++     S  + 
Sbjct: 377 GLQVEDLTQETKRSMRLSDDVQGVLVSQVNENSPAEQAGFRQGNIITKIEEVEVKSVADF 436

Query: 319 MDQVAEIR 326
              + + +
Sbjct: 437 NHALEKYK 444


>5Y28-A nrPDB
          Length = 357

 Score =  333 bits (855), Expect = 5e-92,   Method: Composition-based stats.
 Identities = 130/361 (36%), Positives = 197/361 (54%), Gaps = 35/361 (9%)

Query: 16  GAILLVAMPSLRSLNPLSTPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTNSH---- 71
           G I + +MP ++    +S P   S D+T  SY+ +++ +  AVVN+       N+     
Sbjct: 8   GNIQIQSMPKVKER--VSVP---SKDDTIYSYHDSIKDSIKAVVNISTEKKIKNNFIGGG 62

Query: 72  -------------------NQLEIRTLGSGVIMDQRGYIITNKHVINDADQIIVALQ-DG 111
                               +   R LGSGVI+ + GYI+TN HVI+ AD+I V +    
Sbjct: 63  VFNDPFFQQFFGDLGGMIPKERMERALGSGVIISKDGYIVTNNHVIDGADKIKVTIPGSN 122

Query: 112 RVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQG 171
           + + A LVG+DS +DLAV++I     LPTI  +      +GD+V AIGNP+ +G+++TQG
Sbjct: 123 KEYSATLVGTDSESDLAVIRI-TKDNLPTIKFSDSNDISVGDLVFAIGNPFGVGESVTQG 181

Query: 172 IISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEG 231
           I+SA  + G+     +NF+QTDASIN GNSGGAL++S G L+GINT    K+       G
Sbjct: 182 IVSALNKSGIGINSYENFIQTDASINPGNSGGALIDSRGGLVGINTAIISKTGGN---HG 238

Query: 232 IGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREIAPLHAQGGGIDQLQGIVVNEVSPDG 291
           IGFAIP  +    + +LI+ G++ RGY+G+G ++++         D  +G VV  V  D 
Sbjct: 239 IGFAIPSNMVKDTVTQLIKTGKIERGYLGVGLQDLSGDLQN--SYDNKEGAVVISVEKDS 296

Query: 292 PAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQEY 351
           PA  AGI V DLI  V+ K   +  E  + +  + P   + + V+RD K+    +T+ E 
Sbjct: 297 PAKKAGILVWDLITEVNGKKVKNTNELRNLIGSMLPNQRVTLKVIRDKKERAFTLTLAER 356

Query: 352 P 352
            
Sbjct: 357 K 357


>3STJ-A nrPDB
          Length = 345

 Score =  327 bits (839), Expect = 4e-90,   Method: Composition-based stats.
 Identities = 130/335 (38%), Positives = 185/335 (55%), Gaps = 21/335 (6%)

Query: 33  STPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTNSHN-----------------QLE 75
           S P   +      S    + +  PAVV+V   G  +                        
Sbjct: 1   SIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQP 60

Query: 76  IRTLGSGVIMD-QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINA 134
              LGSGVI++  +GY++TN HVIN A +I + L DGR F+A L+GSD  +D+A+L+I  
Sbjct: 61  FEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQN 120

Query: 135 TGGLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDA 194
              L  I I       +GD  +A+GNP+ LGQT T GI+SA GR GLN  G +NF+QTDA
Sbjct: 121 PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDA 180

Query: 195 SINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRV 254
           SIN GNSGGAL+N  GEL+GINT        G    GIGFAIP  +A  +  +LI  G +
Sbjct: 181 SINRGNSGGALLNLNGELIGINTAILAP---GGGSVGIGFAIPSNMARTLAQQLIDFGEI 237

Query: 255 IRGYIGIGGREIAPLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAIS 314
            RG +GI G E++   A+   +D  +G  V+EV P   +A AG++  D+I S++ KP  S
Sbjct: 238 KRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNS 297

Query: 315 ALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQ 349
             E   ++A   PG+ + + ++R+ K L ++VT+ 
Sbjct: 298 FAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLD 332


>3MH6-A nrPDB
          Length = 456

 Score =  326 bits (836), Expect = 8e-90,   Method: Composition-based stats.
 Identities = 124/338 (36%), Positives = 186/338 (55%), Gaps = 14/338 (4%)

Query: 23  MPSLRSLNPLSTPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTN---------SHNQ 73
           MPS+ S+N +      +T   P ++       +P          +              Q
Sbjct: 23  MPSVVSIN-VEGSTTVNTPRMPRNFQQFFGDDSPFCQEGSPFQSSPFCQGGQGGNGGGQQ 81

Query: 74  LEIRTLGSGVIMD-QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKI 132
            +   LGSGVI+D  +GY++TN HV+++A  I V L DGR F+A +VG D  +D+A+++I
Sbjct: 82  QKFMALGSGVIIDADKGYVVTNNHVVDNATVIKVQLSDGRKFDAKMVGKDPRSDIALIQI 141

Query: 133 NATGGLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQT 192
                L  I +       +GD  +AIGNP+ LG+T+T GI+SA GR GLN    +NF+QT
Sbjct: 142 QNPKNLTAIKMADSDALRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLNAENYENFIQT 201

Query: 193 DASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDG 252
           DA+IN GNSGGALVN  GEL+GINT             GIGFAIP  +   +  +++  G
Sbjct: 202 DAAINRGNSGGALVNLNGELIGINTAILAPDGGN---IGIGFAIPSNMVKNLTSQMVEYG 258

Query: 253 RVIRGYIGIGGREIAPLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPA 312
           +V RG +GI G E+    A+   +D  +G  V++V P+  AA AGI+  D+I S++ KP 
Sbjct: 259 QVKRGELGIMGTELNSELAKAMKVDAQRGAFVSQVLPNSSAAKAGIKAGDVITSLNGKPI 318

Query: 313 ISALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQE 350
            S      QV  +  GS + + ++RD KQ+ + + +Q+
Sbjct: 319 SSFAALRAQVGTMPVGSKLTLGLLRDGKQVNVNLELQQ 356



 Score = 50.1 bits (118), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 2/74 (2%)

Query: 271 AQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSV 330
           A+     + QG+VVN V    PAA  G++  D+II  + +   +  E    +      SV
Sbjct: 374 AEMSNKGKDQGVVVNNVKTGTPAAQIGLKKGDVIIGANQQAVKNIAELRKVLDSKP--SV 431

Query: 331 IPVVVMRDDKQLTL 344
           + + + R D  + L
Sbjct: 432 LALNIQRGDSTIYL 445


>4A8B-A nrPDB
          Length = 436

 Score =  326 bits (836), Expect = 8e-90,   Method: Composition-based stats.
 Identities = 129/335 (38%), Positives = 185/335 (55%), Gaps = 21/335 (6%)

Query: 33  STPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTNSHN-----------------QLE 75
           S P   +      S    + +  PAVV+V   G  +                        
Sbjct: 1   SIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQP 60

Query: 76  IRTLGSGVIMD-QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINA 134
              LGSGVI++  +GY++TN HVIN A +I + L DGR F+A L+GSD  +D+A+L+I  
Sbjct: 61  FEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQN 120

Query: 135 TGGLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDA 194
              L  I I       +GD  +A+GNP+ LGQT T GI+SA GR GLN  G +NF+QTDA
Sbjct: 121 PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDA 180

Query: 195 SINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRV 254
           SIN GN+GGAL+N  GEL+GINT        G    GIGFAIP  +A  +  +LI  G +
Sbjct: 181 SINRGNAGGALLNLNGELIGINTAILAP---GGGSVGIGFAIPSNMARTLAQQLIDFGEI 237

Query: 255 IRGYIGIGGREIAPLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAIS 314
            RG +GI G E++   A+   +D  +G  V+EV P   +A AG++  D+I S++ KP  S
Sbjct: 238 KRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNS 297

Query: 315 ALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQ 349
             E   ++A   PG+ + + ++R+ K L ++VT+ 
Sbjct: 298 FAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLD 332



 Score = 48.2 bits (113), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 23/89 (25%), Positives = 46/89 (51%), Gaps = 6/89 (6%)

Query: 261 IGGREIAPLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMD 320
           + G  ++    + GG    +GI ++EV    PAA AG+Q +D+II V+     S  E   
Sbjct: 348 LEGATLSDGQLKDGG----KGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRK 403

Query: 321 QVAEIRPGSVIPVVVMRDDKQLTLQVTIQ 349
            +A     ++I + ++R ++ + L + ++
Sbjct: 404 VLAAKP--AIIALQIVRGNESIYLLMRLE 430


>4YNN-A nrPDB
          Length = 448

 Score =  316 bits (809), Expect = 1e-86,   Method: Composition-based stats.
 Identities = 127/329 (38%), Positives = 186/329 (56%), Gaps = 32/329 (9%)

Query: 50  AVRRAAPAVVNVYNRGLNTN---------------------SHNQLEIRTLGSGVIMD-Q 87
            ++ A PA+VNV  +G   N                          +  ++GSGVI+D +
Sbjct: 25  VLKNAMPAIVNVAVQGYLPNNMASGNADDDDGENSKQPSRIPEKGRKFESIGSGVIIDPK 84

Query: 88  RGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARR 147
            G IITN HVI +A+ I V LQDGR  +A L+G DS TDLAVLKI+A   L ++ I    
Sbjct: 85  NGIIITNDHVIRNANLITVTLQDGRRLKARLIGGDSETDLAVLKIDAKN-LKSLVIGDSD 143

Query: 148 VPHIGDVVLAIGNPYNL-----GQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSG 202
              +GD V+AIGNP+ L      Q+ T GI+SA  R  LN  G +NF+QTDA+IN GN+G
Sbjct: 144 KLEVGDYVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVENFIQTDAAINPGNAG 203

Query: 203 GALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIG 262
           GALVN+ GEL+GINT             GIGFAIP  +A  +  ++I+ G + RG +GI 
Sbjct: 204 GALVNAKGELIGINTAIISPYGGN---VGIGFAIPINMAKDVAQQIIKFGSIHRGLMGIF 260

Query: 263 GREIAPLHAQGGGI-DQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQ 321
            + + P  AQ  G  +  QG +V++V+ + PA  AG++  D+I+ +++     A +    
Sbjct: 261 VQHLTPELAQSMGYAEDFQGALVSQVNQNSPAQLAGLKSGDVIVQINDTKITQATQVKTT 320

Query: 322 VAEIRPGSVIPVVVMRDDKQLTLQVTIQE 350
           ++ +R GS   + ++RD+K LTL V + +
Sbjct: 321 ISLLRAGSTAKIKILRDNKPLTLDVEVTD 349



 Score = 38.1 bits (87), Expect = 0.006,   Method: Composition-based stats.
 Identities = 14/58 (24%), Positives = 21/58 (36%), Gaps = 2/58 (3%)

Query: 290 DGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVT 347
                 AG++  D+IIS +  P            E   G  + V V+R    L L + 
Sbjct: 393 TSAGWRAGLRPGDIIISANKTPVKDIKSLQAVAHE--KGKQLLVQVLRGAGALYLLII 448


>2QF3-A nrPDB
          Length = 243

 Score =  316 bits (809), Expect = 1e-86,   Method: Composition-based stats.
 Identities = 230/230 (100%), Positives = 230/230 (100%)

Query: 27  RSLNPLSTPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMD 86
           RSLNPLSTPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMD
Sbjct: 14  RSLNPLSTPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMD 73

Query: 87  QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINAR 146
           QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINAR
Sbjct: 74  QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINAR 133

Query: 147 RVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALV 206
           RVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALV
Sbjct: 134 RVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALV 193

Query: 207 NSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIR 256
           NSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIR
Sbjct: 194 NSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIR 243


>3PV2-A nrPDB
          Length = 451

 Score =  314 bits (805), Expect = 3e-86,   Method: Composition-based stats.
 Identities = 127/336 (37%), Positives = 182/336 (54%), Gaps = 36/336 (10%)

Query: 50  AVRRAAPAVVNVYNRGLNTN-------------------------SHNQLEIRTLGSGVI 84
            ++   PA+VNV  +G   N                              +  ++GSGVI
Sbjct: 24  VLKNIMPAIVNVAVQGYLPNDVTPPGSAGNDEENQPNNRPPQSRMPEKGRKFESIGSGVI 83

Query: 85  MD-QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPI 143
           +D   G IITN HVI +A  I V LQDGR  +A L+G DS TDLAVLKI+A   L ++ I
Sbjct: 84  IDPNNGVIITNDHVIRNASLITVTLQDGRRLKARLIGGDSETDLAVLKIDAKN-LKSLVI 142

Query: 144 NARRVPHIGDVVLAIGNPYNL-----GQTITQGIISATGRIGLNPTGRQNFLQTDASINH 198
                  +GD V+AIGNP+ L      Q+ T GI+SA  R  LN  G +NF+QTDA+IN 
Sbjct: 143 GDSDKLEVGDFVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVENFIQTDAAINP 202

Query: 199 GNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGY 258
           GNSGGALVN+ GEL+GINT             GIGFAIP  +   +  ++I+ G + RG 
Sbjct: 203 GNSGGALVNAKGELIGINTAILSPYGGN---VGIGFAIPINMVKDVAQQIIKFGSIHRGL 259

Query: 259 IGIGGREIAPLHAQGGGID-QLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALE 317
           +GI  + + P  AQ  G     QG +V++V+P+ PA  AG++  D+I  +++     A +
Sbjct: 260 MGIFVQHLTPELAQAMGYPEDFQGALVSQVNPNSPAELAGLKAGDIITQINDTKITQATQ 319

Query: 318 TMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQEYPA 353
               ++ +R GS + ++V RD+K LTL   + +  +
Sbjct: 320 VKTTISLLRVGSTVKIIVERDNKPLTLSAVVTDIKS 355



 Score = 42.0 bits (97), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 17/78 (21%), Positives = 29/78 (37%), Gaps = 2/78 (2%)

Query: 261 IGGREIAPLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMD 320
           + G  +     +      + G+ V   S +     AGI+  D+IIS + KP         
Sbjct: 367 LYGLALRAFEQESPPHGNVIGVQVVGASENSAGWRAGIRPGDIIISANKKPVTDVKSLQT 426

Query: 321 QVAEIRPGSVIPVVVMRD 338
              E +    + V V+R 
Sbjct: 427 IAQEKK--KELLVQVLRG 442


>3PV4-A nrPDB
          Length = 354

 Score =  310 bits (794), Expect = 6e-85,   Method: Composition-based stats.
 Identities = 120/288 (41%), Positives = 170/288 (59%), Gaps = 11/288 (3%)

Query: 70  SHNQLEIRTLGSGVIMD-QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLA 128
                +  ++GSGVI+D   G IITN HVI +A  I V LQDGR  +A L+G DS TDLA
Sbjct: 69  PEKGRKFESIGSGVIIDPNNGVIITNDHVIRNASLITVTLQDGRRLKARLIGGDSETDLA 128

Query: 129 VLKINATGGLPTIPINARRVPHIGDVVLAIGNPYNL-----GQTITQGIISATGRIGLNP 183
           VLKI+A   L ++ I       +GD V+AIGNP+ L      Q+ T GI+SA  R  LN 
Sbjct: 129 VLKIDAKN-LKSLVIGDSDKLEVGDFVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNI 187

Query: 184 TGRQNFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATK 243
            G +NF+QTDA+IN GNSGGALVN+ GEL+GINT             GIGFAIP  +   
Sbjct: 188 EGVENFIQTDAAINPGNSGGALVNAKGELIGINTAILSPYGGN---VGIGFAIPINMVKD 244

Query: 244 IMDKLIRDGRVIRGYIGIGGREIAPLHAQGGGID-QLQGIVVNEVSPDGPAANAGIQVND 302
           +  ++I+ G + RG +GI  + + P  AQ  G     QG +V++V+P+ PA  AG++  D
Sbjct: 245 VAQQIIKFGSIHRGLMGIFVQHLTPELAQAMGYPEDFQGALVSQVNPNSPAELAGLKAGD 304

Query: 303 LIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQE 350
           +I  +++     A +    ++ +R GS + ++V RD+K LTL   + +
Sbjct: 305 IITQINDTKITQATQVKTTISLLRVGSTVKIIVERDNKPLTLSAVVTD 352


>4YO1-A nrPDB
          Length = 351

 Score =  309 bits (792), Expect = 9e-85,   Method: Composition-based stats.
 Identities = 127/329 (38%), Positives = 186/329 (56%), Gaps = 32/329 (9%)

Query: 50  AVRRAAPAVVNVYNRGLNTN---------------------SHNQLEIRTLGSGVIMD-Q 87
            ++ A PA+VNV  +G   N                          +  ++GSGVI+D +
Sbjct: 25  VLKNAMPAIVNVAVQGYLPNNMASGNADDDDGENSKQPSRIPEKGRKFESIGSGVIIDPK 84

Query: 88  RGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARR 147
            G IITN HVI +A+ I V LQDGR  +A L+G DS TDLAVLKI+A   L ++ I    
Sbjct: 85  NGIIITNDHVIRNANLITVTLQDGRRLKARLIGGDSETDLAVLKIDAKN-LKSLVIGDSD 143

Query: 148 VPHIGDVVLAIGNPYNL-----GQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSG 202
              +GD V+AIGNP+ L      Q+ T GI+SA  R  LN  G +NF+QTDA+IN GN+G
Sbjct: 144 KLEVGDYVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVENFIQTDAAINPGNAG 203

Query: 203 GALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIG 262
           GALVN+ GEL+GINT             GIGFAIP  +A  +  ++I+ G + RG +GI 
Sbjct: 204 GALVNAKGELIGINTAIISPYGGN---VGIGFAIPINMAKDVAQQIIKFGSIHRGLMGIF 260

Query: 263 GREIAPLHAQGGGI-DQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQ 321
            + + P  AQ  G  +  QG +V++V+ + PA  AG++  D+I+ +++     A +    
Sbjct: 261 VQHLTPELAQSMGYAEDFQGALVSQVNQNSPAQLAGLKSGDVIVQINDTKITQATQVKTT 320

Query: 322 VAEIRPGSVIPVVVMRDDKQLTLQVTIQE 350
           ++ +R GS   + ++RD+K LTL V + +
Sbjct: 321 ISLLRAGSTAKIKILRDNKPLTLDVEVTD 349


>3QO6-A nrPDB
          Length = 348

 Score =  303 bits (776), Expect = 7e-83,   Method: Composition-based stats.
 Identities = 116/339 (34%), Positives = 179/339 (52%), Gaps = 28/339 (8%)

Query: 32  LSTPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTNSH--NQLEI-RTLGSGVIMDQR 88
           +STP+   TDE  A+  L  +   P+VV + N  +  ++   + LE+ +  GSG + D++
Sbjct: 6   VSTPKKLQTDEL-ATVRL-FQENTPSVVYITNLAVRQDAFTLDVLEVPQGSGSGFVWDKQ 63

Query: 89  GYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINAT-GGLPTIPINARR 147
           G+I+TN HVI  A  + V L D   F+A +VG D   D+AVL+I+A    L  IP+    
Sbjct: 64  GHIVTNYHVIRGASDLRVTLADQTTFDAKVVGFDQDKDVAVLRIDAPKNKLRPIPVGVSA 123

Query: 148 VPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTG---RQNFLQTDASINHGNSGGA 204
              +G  V AIGNP+ L  T+T G+IS   R   +       Q+ +QTDA+IN GNSGG 
Sbjct: 124 DLLVGQKVFAIGNPFGLDHTLTTGVISGLRREISSAATGRPIQDVIQTDAAINPGNSGGP 183

Query: 205 LVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGR 264
           L++S G L+GINT  +  S       G+GF+IP      I+D+L+R G+V R  +GI   
Sbjct: 184 LLDSSGTLIGINTAIYSPSGA---SSGVGFSIPVDTVGGIVDQLVRFGKVTRPILGI--- 237

Query: 265 EIAPLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQ-----------VNDLIISVDNKPAI 313
           + AP   Q      + G++V +  P GPA  AG+Q           + D+I SV+     
Sbjct: 238 KFAPD--QSVEQLGVSGVLVLDAPPSGPAGKAGLQSTKRDGYGRLVLGDIITSVNGTKVS 295

Query: 314 SALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQEYP 352
           +  +    + + + G  + V V+R D +  + VT++  P
Sbjct: 296 NGSDLYRILDQCKVGDEVTVEVLRGDHKEKISVTLEPKP 334


>3NUM-A nrPDB
          Length = 332

 Score =  299 bits (766), Expect = 1e-81,   Method: Composition-based stats.
 Identities = 104/322 (32%), Positives = 169/322 (52%), Gaps = 29/322 (9%)

Query: 46  SYNL---AVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDAD 102
            YN     V + APAVV++        S  ++ + + GSG I+ + G I+TN HV+ +  
Sbjct: 12  KYNFIADVVEKIAPAVVHIELFRKLPFSKREVPVAS-GSGFIVSEDGLIVTNAHVVTNKH 70

Query: 103 QIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGNPY 162
           ++ V L++G  +EA +   D   D+A++KI+  G LP + +        G+ V+AIG+P+
Sbjct: 71  RVKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRPGEFVVAIGSPF 130

Query: 163 NLGQTITQGIISATGRIGLNPTGRQ---NFLQTDASINHGNSGGALVNSLGELMGINTLS 219
           +L  T+T GI+S T R G     R    +++QTDA IN+GN+GG LVN  GE++GINTL 
Sbjct: 131 SLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNAGGPLVNLDGEVIGINTL- 189

Query: 220 FDKSNDGETPEGIGFAIPFQLATKIM----DKLIRDGRVI-RGYIGIGGREIAPLHAQGG 274
                  +   GI FAIP     K +    D+  +   +  + YIGI    +    A+  
Sbjct: 190 -------KVTAGISFAIPSDKIKKFLTESHDRQAKGKAITKKKYIGIRMMSLTSSKAKEL 242

Query: 275 GI------DQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPG 328
                   D + G  + EV PD PA   G++ ND+IIS++ +  +SA +  D +   +  
Sbjct: 243 KDRHRDFPDVISGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVSANDVSDVI---KRE 299

Query: 329 SVIPVVVMRDDKQLTLQVTIQE 350
           S + +VV R ++ + + V  +E
Sbjct: 300 STLNMVVRRGNEDIMITVIPEE 321


>4RI0-A nrPDB
          Length = 332

 Score =  293 bits (750), Expect = 7e-80,   Method: Composition-based stats.
 Identities = 111/343 (32%), Positives = 173/343 (50%), Gaps = 44/343 (12%)

Query: 29  LNPLSTPQFDSTDETPASYNL---AVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIM 85
           L+ LS+P++         +N     V + APAVV++     +      + + + GSG IM
Sbjct: 1   LHQLSSPRY--------KFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPL-SSGSGFIM 51

Query: 86  DQRGYIITNKHVIN------DADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLP 139
            + G IITN HV++         Q+ V LQ+G  +EA +   D  +D+A +KI+    LP
Sbjct: 52  SEAGLIITNAHVVSSNSAAPGRQQLKVQLQNGDSYEATIKDIDKKSDIATIKIHPKKKLP 111

Query: 140 TIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQ---NFLQTDASI 196
            + +        G+ V+AIG+P+ L  T+T GI+S   R G     R    +++QTDA I
Sbjct: 112 VLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQREGRELGLRDSDMDYIQTDAII 171

Query: 197 NHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIM----DKLIRDG 252
           N+GN+GG LVN  GE++GINTL        +   GI FAIP    T+ +    DK I+D 
Sbjct: 172 NYGNAGGPLVNLDGEVIGINTL--------KVTAGISFAIPSDRITRFLTEFQDKQIKDW 223

Query: 253 RVIRGYIGIGGREIAP-----LHAQGGGIDQL-QGIVVNEVSPDGPAANAGIQVNDLIIS 306
           +  + +IGI  R I P     L A      ++  GI V EV+P+ P+   GIQ  D+I+ 
Sbjct: 224 K--KRFIGIRMRTITPSLVDELKASNPDFPEVSSGIYVQEVAPNSPSQRGGIQDGDIIVK 281

Query: 307 VDNKPAISALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQ 349
           V+ +P + + E  + V    P   + + V R +  L   +  +
Sbjct: 282 VNGRPLVDSSELQEAVLTESP---LLLEVRRGNDDLLFSIAPE 321


>5T69-A nrPDB
          Length = 367

 Score =  291 bits (745), Expect = 3e-79,   Method: Composition-based stats.
 Identities = 118/357 (33%), Positives = 168/357 (47%), Gaps = 39/357 (10%)

Query: 31  PLSTPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLN---------------------TN 69
           P+ T Q      + +    AV R+ PAVV +    +                        
Sbjct: 15  PVITAQASVPLTSESFVAAAVSRSGPAVVRIDTETVVTRRTDPILDDPFFQEFFGRSFPV 74

Query: 70  SHNQLEIRTLGSGVIMDQRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAV 129
              +  I   GSG I+D  G I+TN HV++ A +++V L+DGR F+  + G+D +TDLAV
Sbjct: 75  PPRERRIAGQGSGFIIDNSGIILTNAHVVDGASKVVVTLRDGRTFDGQVRGTDEVTDLAV 134

Query: 130 LKINATG-GLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLN---PTG 185
           +KI   G  LP  P+       +GD  +A+GNP  L  T+T GIIS  GR       P  
Sbjct: 135 VKIEPQGSALPVAPLGTSSNLQVGDWAIAVGNPVGLDNTVTLGIISTLGRSAAQAGIPDK 194

Query: 186 RQNFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIM 245
           R  F+QTDA+IN GN+GG L+N+ GE++GINT             GIGFAIP   A  I 
Sbjct: 195 RVEFIQTDAAINPGNAGGPLLNARGEVIGINTAI------RADATGIGFAIPIDQAKAIQ 248

Query: 246 DKLIRDGRVIRGYIGIGGREIAPLHAQGGG--------IDQLQGIVVNEVSPDGPAANAG 297
           + L   G V   YIG+    I    AQ           I ++ GI+V  V P  PA  AG
Sbjct: 249 NTLAAGGTVPHPYIGVQMMNITVDQAQQNNRNPNSPFIIPEVDGILVMRVLPGTPAERAG 308

Query: 298 IQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQEYPAT 354
           I+  D+I++VD  P          V +      + + ++R D++L+L V   +    
Sbjct: 309 IRRGDVIVAVDGTPISDGARLQRIVEQAGLNKALKLDLLRGDRRLSLTVQTAQLRNP 365


>2R3U-A nrPDB
          Length = 211

 Score =  281 bits (720), Expect = 2e-76,   Method: Composition-based stats.
 Identities = 210/210 (100%), Positives = 210/210 (100%)

Query: 43  TPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDAD 102
           TPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDAD
Sbjct: 2   TPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDAD 61

Query: 103 QIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGNPY 162
           QIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGNPY
Sbjct: 62  QIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGNPY 121

Query: 163 NLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTLSFDK 222
           NLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTLSFDK
Sbjct: 122 NLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTLSFDK 181

Query: 223 SNDGETPEGIGFAIPFQLATKIMDKLIRDG 252
           SNDGETPEGIGFAIPFQLATKIMDKLIRDG
Sbjct: 182 SNDGETPEGIGFAIPFQLATKIMDKLIRDG 211


>5M3O-A nrPDB
          Length = 334

 Score =  273 bits (698), Expect = 8e-74,   Method: Composition-based stats.
 Identities = 97/323 (30%), Positives = 163/323 (50%), Gaps = 30/323 (9%)

Query: 45  ASYNL---AVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDA 101
           + YN     V + APAVV +     +     ++ I + GSG ++   G I+TN HV+ D 
Sbjct: 13  SQYNFIADVVEKTAPAVVYIEILDRHPFLGREVPI-SNGSGFVVAADGLIVTNAHVVADR 71

Query: 102 DQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGNP 161
            ++ V L  G  +EA++   D + D+A L+I     LPT+P+        G+ V+A+G+P
Sbjct: 72  RRVRVRLLSGDTYEAVVTAVDPVADIATLRIQTKEPLPTLPLGRSADVRQGEFVVAMGSP 131

Query: 162 YNLGQTITQGIISATGRIGLN---PTGRQNFLQTDASINHGNSGGALVNSLGELMGINTL 218
           + L  TIT GI+S+  R   +   P     ++QTDA+I+ GNSGG LVN  GE++G+NT+
Sbjct: 132 FALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAAIDFGNSGGPLVNLDGEVIGVNTM 191

Query: 219 SFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVI------RGYIGIGGREIAP---- 268
                   +   GI FAIP     + + +  +           R YIG+    ++P    
Sbjct: 192 --------KVTAGISFAIPSDRLREFLHRGEKKNSSSGISGSQRRYIGVMMLTLSPSILA 243

Query: 269 -LHAQGGGIDQLQ-GIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIR 326
            L  +      +Q G+++++V    PA  AG++  D+I+++  +   +A +  + V   R
Sbjct: 244 ELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEQMVQNAEDVYEAV---R 300

Query: 327 PGSVIPVVVMRDDKQLTLQVTIQ 349
             S + V + R  + LTL VT +
Sbjct: 301 TQSQLAVQIRRGRETLTLYVTPE 323


>4FLN-A nrPDB
          Length = 539

 Score =  270 bits (690), Expect = 7e-73,   Method: Composition-based stats.
 Identities = 74/349 (21%), Positives = 143/349 (40%), Gaps = 31/349 (8%)

Query: 24  PSLRSLNPLSTPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTN----SHNQLEIRTL 79
           P       LS    D   + PA  + A      AVV VY      +       Q +  + 
Sbjct: 19  PKKEKKESLSDFSRDQQTD-PAKIHDA--SFLNAVVKVYCTHTAPDYSLPWQKQRQFTST 75

Query: 80  GSGVIMDQRGYIITNKHVINDADQIIVALQ-DGRVFEALLVGSDSLTDLAVLKINATGGL 138
           GS  ++   G ++TN H +    Q+ V  + D R + A ++      D+A+L + +    
Sbjct: 76  GSAFMIG-DGKLLTNAHCVEHDTQVKVKRRGDDRKYVAKVLVRGVDCDIALLSVESEDFW 134

Query: 139 P-TIPINARRVPHIGDVVLAIGNPYNLGQ-TITQGIISATGRIGLNPTGRQNF--LQTDA 194
               P+    +P + D V  +G P      ++T+G++S    +     G  +   +Q DA
Sbjct: 135 KGAEPLRLGHLPRLQDSVTVVGYPLGGDTISVTKGVVSRIE-VTSYAHGSSDLLGIQIDA 193

Query: 195 SINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRV 254
           +IN GNSGG   N  GE +G+    +      E  E IG+ IP  + +  +    R+G+ 
Sbjct: 194 AINPGNSGGPAFNDQGECIGVAFQVYRS----EETENIGYVIPTTVVSHFLTDYERNGKY 249

Query: 255 I-RGYIGIGGREI-APLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPA 312
                +G+  +++  P   +   +   +G++V  V P   A+   ++  D+I+S D+   
Sbjct: 250 TGYPCLGVLLQKLENPALRECLKVPTNEGVLVRRVEPTSDASKV-LKEGDVIVSFDDLHV 308

Query: 313 ----------ISALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQEY 351
                        +     +++   G +  + ++R  +   +QV ++  
Sbjct: 309 GCEGTVPFRSSERIAFRYLISQKFAGDIAEIGIIRAGEHKKVQVVLRPR 357


>5ILB-A nrPDB
          Length = 474

 Score =  269 bits (688), Expect = 1e-72,   Method: Composition-based stats.
 Identities = 69/315 (21%), Positives = 129/315 (40%), Gaps = 29/315 (9%)

Query: 57  AVVNVYNRGLNTN----SHNQLEIRTLGSGVIMDQRGYIITNKHVINDADQIIVALQ-DG 111
           AVV VY      +       Q +  + GS  ++   G ++TN H +    Q+ V  + D 
Sbjct: 9   AVVKVYCTHTAPDYSLPWQKQRQFTSTGSAFMIG-DGKLLTNAHCVEHDTQVKVKRRGDD 67

Query: 112 RVFEALLVGSDSLTDLAVLKINATGGLP-TIPINARRVPHIGDVVLAIGNPYNLGQ-TIT 169
           R + A ++      D+A+L + +        P+    +P + D V  +G P      ++T
Sbjct: 68  RKYVAKVLVRGVDCDIALLSVESEDFWKGAEPLRLGHLPRLQDSVTVVGYPLGGDTISVT 127

Query: 170 QGIISATGRIGLNPTGRQNF--LQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGE 227
           +G++S    +     G  +   +Q DA+IN GNSGG   N  GE +G+    +      E
Sbjct: 128 KGVVSRIE-VTSYAHGSSDLLGIQIDAAINPGNSGGPAFNDQGECIGVAFQVYRS----E 182

Query: 228 TPEGIGFAIPFQLATKIMDKLIRDGRVIR-GYIGIGGR--EIAPLHAQGGGIDQLQGIVV 284
             E IG+ IP  + +  +    R+G+      +GI  +  E   L    G     +G+ +
Sbjct: 183 ETENIGYVIPTTVVSHFLTDYERNGKYTGFPVLGIEWQKMENPDLRKSMGMESHQKGVRI 242

Query: 285 NEVSPDGPAANAGIQVNDLIISVDNKPAISALET----------MDQVAEIRPGSVIPVV 334
             + P  P +   ++ +D+I+S D     +                 +++   G    V 
Sbjct: 243 RRIEPTAPESQV-LKPSDIILSFDGVNIANDGTVPFRHGERIGFSYLISQKYTGDSALVK 301

Query: 335 VMRDDKQLTLQVTIQ 349
           V+R+ + L   + + 
Sbjct: 302 VLRNKEILEFNIKLA 316


>4IC6-A nrPDB
          Length = 368

 Score =  268 bits (684), Expect = 3e-72,   Method: Composition-based stats.
 Identities = 109/358 (30%), Positives = 175/358 (48%), Gaps = 31/358 (8%)

Query: 24  PSLRSLNPLSTPQFDSTDETPASYNLA--VRRAAPAVVNVYNRGLNTNSHNQLEIR---T 78
           PS+ ++  +S   F +    P    +     +   +VVN+++  L         +     
Sbjct: 6   PSVATVEDVSPTVFPAGPLFPTEGRIVQLFEKNTYSVVNIFDVTLRPQLKMTGVVEIPEG 65

Query: 79  LGSGVIMDQRGYIITNKHVINDA-----------DQIIVALQDG--RVFEALLVGSDSLT 125
            GSGV+ D +GYI+TN HVI +A            ++ +   DG  + FE  LVG+D   
Sbjct: 66  NGSGVVWDGQGYIVTNYHVIGNALSRNPSPGDVVGRVNILASDGVQKNFEGKLVGADRAK 125

Query: 126 DLAVLKINATGGL-PTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPT 184
           DLAVLK++A   L   I +       +G   LAIGNP+    T+T G+IS   R   + T
Sbjct: 126 DLAVLKVDAPETLLKPIKVGQSNSLKVGQQCLAIGNPFGFDHTLTVGVISGLNRDIFSQT 185

Query: 185 GRQ--NFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLAT 242
           G      +QTDA+IN GN+GG L++S G L+GINT  F ++    T  G+GFAIP     
Sbjct: 186 GVTIGGGIQTDAAINPGNAGGPLLDSKGNLIGINTAIFTQTG---TSAGVGFAIPSSTVL 242

Query: 243 KIMDKLIRDGRVIRGYIGIGGREIAPLH----AQGGGIDQLQGIVVNE---VSPDGPAAN 295
           KI+ +LI+  +V+R  I I        +      G  + Q+ G  + E   + P      
Sbjct: 243 KIVPQLIQFSKVLRAGINIELAPDPVANQLNVRNGALVLQVPGKSLAEKAGLHPTSRGFA 302

Query: 296 AGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQEYPA 353
             I + D+I++VD+KP  +  E M  + E   G  + + + R ++ L L+++++E  +
Sbjct: 303 GNIVLGDIIVAVDDKPVKNKAELMKILDEYSVGDKVTLKIKRGNEDLELKISLEEKSS 360


>6IEO-A nrPDB
          Length = 314

 Score =  257 bits (656), Expect = 6e-69,   Method: Composition-based stats.
 Identities = 103/283 (36%), Positives = 147/283 (51%), Gaps = 23/283 (8%)

Query: 80  GSGVIMDQRGYIITNKHVINDAD------QIIVALQDGRVFEALLVGSDSLTDLAVLKIN 133
           GSGVI+D RGYI+TN HVI++A       +  V   DG+   A LVG D  TDLAVLK++
Sbjct: 32  GSGVIVDGRGYIVTNNHVISEAANNPSQFKTTVVFNDGKEVPANLVGRDPKTDLAVLKVD 91

Query: 134 ATGGLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGR------IGLNPTGRQ 187
               L    +       +GD VLA+G P  L  T+TQGI+SA  R       G +     
Sbjct: 92  NVDNLTVARLGDSSKVRVGDEVLAVGAPLGLRSTVTQGIVSALHRPVPLSGEGSDTDTVI 151

Query: 188 NFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDK 247
           + +QTDASINHGNSGG L++   +++GINT     S+      G+GFAIP      + + 
Sbjct: 152 DAIQTDASINHGNSGGPLIDMDAQVIGINTAGKSLSDS---ASGLGFAIPVNEMKLVANS 208

Query: 248 LIRDGRVIRGYIGIGGREIAPLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISV 307
           LI+DG+++   +GI  R ++   A         G  V  V    PA   GI  ND+I+ V
Sbjct: 209 LIKDGKIVHPTLGISTRSVSNAIAS--------GAQVANVKAGSPAQKGGILENDVIVKV 260

Query: 308 DNKPAISALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQE 350
            N+    + E +  V ++  G   P+ V+R+ + +TL V    
Sbjct: 261 GNRAVADSDEFVVAVRQLAIGQDAPIEVVREGRHVTLTVKPDP 303


>5JYK-A nrPDB
          Length = 566

 Score =  243 bits (621), Expect = 7e-65,   Method: Composition-based stats.
 Identities = 67/324 (20%), Positives = 126/324 (38%), Gaps = 30/324 (9%)

Query: 50  AVRRAAP---AVVNVYNRGLNTN----SHNQLEIRTLGSGVIMDQRGYIITNKHVINDAD 102
            V +  P   AVV V+      N       + +  +  SG I+  R  ++TN H +    
Sbjct: 91  TVVKVVPSMDAVVKVFCVHTEPNFSLPWQRKRQYSSGSSGFIIGGR-RVLTNAHSVEHHT 149

Query: 103 QIIVALQ-DGRVFEALLVGSDSLTDLAVLKINATGGLPTI-PINARRVPHIGDVVLAIGN 160
           Q+ +  +     + A ++   +  D+A+L +        + P+    +P + D V  +G 
Sbjct: 150 QVKLKKRGSDTKYLATVLAIGTECDIALLTVTDDEFWEGVSPVEFGDLPALQDAVTVVGY 209

Query: 161 PYNLGQ-TITQGIISATGRIGLNPTGRQNF-LQTDASINHGNSGGALVNSLGELMGINTL 218
           P      ++T G++S    +       +   LQ DA+IN GNSGG   N  G+ +GI   
Sbjct: 210 PIGGDTISVTSGVVSRMEILSYVHGSTELLGLQIDAAINSGNSGGPAFNDKGKCVGIAFQ 269

Query: 219 SFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIR-GYIGIGGR--EIAPLHAQGGG 275
           S       E  E IG+ IP  +    +    +  +      +GI  +  E   L    G 
Sbjct: 270 SLKH----EDAENIGYVIPTPVIVHFIQDYEKHDKYTGFPVLGIEWQKMENPDLRKSMGM 325

Query: 276 IDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALET----------MDQVAEI 325
               +G+ +  + P  P +   ++ +D+I+S D     +                 +++ 
Sbjct: 326 ESHQKGVRIRRIEPTAPESQV-LKPSDIILSFDGVNIANDGTVPFRHGERIGFSYLISQK 384

Query: 326 RPGSVIPVVVMRDDKQLTLQVTIQ 349
             G    V V+R+ + L   + + 
Sbjct: 385 YTGDSALVKVLRNKEILEFNIKLA 408


>1L1J-A nrPDB
          Length = 239

 Score =  235 bits (600), Expect = 2e-62,   Method: Composition-based stats.
 Identities = 81/235 (34%), Positives = 116/235 (49%), Gaps = 27/235 (11%)

Query: 50  AVRRAAPAVVNVYNRGLNTNSHN-------------------QLEIRTLGSGVIMDQRGY 90
            V   APAVV +        S                     + ++ +LGSG I D  GY
Sbjct: 9   VVEACAPAVVKIDVVKTVKTSFFDPYFEQFFKKWFGELPPGFERQVASLGSGFIFDPEGY 68

Query: 91  IITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINA-TGGLPTIPINARRVP 149
           I+TN HV+  AD I V + DG  ++A  +G D   D+AV+KI A     P +        
Sbjct: 69  ILTNYHVVGGADNITVTMLDGSKYDAEYIGGDEELDIAVIKIKASDKKFPYLEFGDSDKV 128

Query: 150 HIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNF---LQTDASINHGNSGGALV 206
            IG+  +AIGNP     T+T G++SAT R    P G   +   +QTDA+IN GNSGG L+
Sbjct: 129 KIGEWAIAIGNPLGFQHTVTVGVVSATNRRIPKPDGSGYYVGLIQTDAAINPGNSGGPLL 188

Query: 207 NSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGI 261
           N  GE++GINT   +     +    +GFAIP     K +D ++   +V + Y+G+
Sbjct: 189 NIHGEVIGINTAIVNP----QEAVNLGFAIPINTVKKFLDTILTQKKVEKAYLGV 239


>3STI-A nrPDB
          Length = 245

 Score =  234 bits (598), Expect = 4e-62,   Method: Composition-based stats.
 Identities = 99/242 (40%), Positives = 131/242 (54%), Gaps = 21/242 (8%)

Query: 33  STPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTNSHN-----------------QLE 75
           S P   +      S    + +  PAVV+V   G  +                        
Sbjct: 1   SIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQP 60

Query: 76  IRTLGSGVIMD-QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINA 134
              LGSGVI++  +GY++TN HVIN A +I + L DGR F+A L+GSD  +D+A+L+I  
Sbjct: 61  FEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQN 120

Query: 135 TGGLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDA 194
              L  I I       +GD  +A+GNP+ LGQT T GI+SA GR GLN  G +NF+QTDA
Sbjct: 121 PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDA 180

Query: 195 SINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRV 254
           SIN GNSGGAL+N  GEL+GINT        G    GIGFAIP  +A  +  +LI  G +
Sbjct: 181 SINRGNSGGALLNLNGELIGINTAILAP---GGGSVGIGFAIPSNMARTLAQQLIDFGEI 237

Query: 255 IR 256
           + 
Sbjct: 238 LE 239


>3TJO-A nrPDB
          Length = 231

 Score =  232 bits (592), Expect = 1e-61,   Method: Composition-based stats.
 Identities = 75/208 (36%), Positives = 116/208 (55%), Gaps = 15/208 (7%)

Query: 46  SYNL---AVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDAD 102
            YN     V + APAVV++        S  ++ + + GSG I+ + G I+TN HV+ +  
Sbjct: 29  KYNFIADVVEKIAPAVVHIELFRKLPFSKREVPVAS-GSGFIVSEDGLIVTNAHVVTNKH 87

Query: 103 QIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGNPY 162
           ++ V L++G  +EA +   D   D+A++KI+  G LP + +        G+ V+AIG+P+
Sbjct: 88  RVKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRPGEFVVAIGSPF 147

Query: 163 NLGQTITQGIISATGRIGLNPTGRQ---NFLQTDASINHGNSGGALVNSLGELMGINTLS 219
           +L  T+T GI+S T R G     R    +++QTDA IN+GN+GG LVN  GE++GINTL 
Sbjct: 148 SLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNAGGPLVNLDGEVIGINTL- 206

Query: 220 FDKSNDGETPEGIGFAIPFQLATKIMDK 247
                  +   GI FAIP     K + +
Sbjct: 207 -------KVTAGISFAIPSDKIKKFLTE 227


>2Z9I-A nrPDB
          Length = 324

 Score =  216 bits (549), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 107/325 (32%), Positives = 152/325 (46%), Gaps = 38/325 (11%)

Query: 44  PASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDA-- 101
           P S      +  P+VV      L T+   Q E    GSG+I+   G I+TN HVI  A  
Sbjct: 5   PGSVEQVAAKVVPSVVM-----LETDLGRQSE---EGSGIILSAEGLILTNNHVIAAAAK 56

Query: 102 -------DQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDV 154
                   +  V   DGR     +VG+D  +D+AV+++    GL  I + +     +G  
Sbjct: 57  PPLGSPPPKTTVTFSDGRTAPFTVVGADPTSDIAVVRVQGVSGLTPISLGSSSDLRVGQP 116

Query: 155 VLAIGNPYNLGQTITQGIISATGR--IGLNPTGRQN----FLQTDASINHGNSGGALVNS 208
           VLAIG+P  L  T+T GI+SA  R        G QN     +QTDA+IN GNSGGALVN 
Sbjct: 117 VLAIGSPLGLEGTVTTGIVSALNRPVSTTGEAGNQNTVLDAIQTDAAINPGNSGGALVNM 176

Query: 209 LGELMGIN----TLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGR 264
             +L+G+N    TL  D ++      G+GFAIP   A +I D+LI  G+     +G+   
Sbjct: 177 NAQLVGVNSAIATLGADSADAQSGSIGLGFAIPVDQAKRIADELISTGKASHASLGVQVT 236

Query: 265 EIAPLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAE 324
                           G  + EV   G AANAG+    ++  VD++P  SA   +  V  
Sbjct: 237 NDKDTL----------GAKIVEVVAGGAAANAGVPKGVVVTKVDDRPINSADALVAAVRS 286

Query: 325 IRPGSVIPVVVMR-DDKQLTLQVTI 348
             PG+ + +          T+QVT+
Sbjct: 287 KAPGATVALTFQDPSGGSRTVQVTL 311


>4IC5-A nrPDB
          Length = 291

 Score =  206 bits (525), Expect = 9e-54,   Method: Composition-based stats.
 Identities = 75/227 (33%), Positives = 107/227 (47%), Gaps = 22/227 (9%)

Query: 51  VRRAAPAVVNVYNRGLNTNS-------HNQLEIRTLGSGVIMDQRGYIITNKHVINDADQ 103
            ++ +P+VV +    L   S           +I   GSG + D+ G+I+TN HVI     
Sbjct: 46  FQKTSPSVVYIEAIELPKTSSGDILTDEENGKIEGTGSGFVWDKLGHIVTNYHVIAKLAT 105

Query: 104 IIVALQDGRVF-----------EALLVGSDSLTDLAVLKINATG-GLPTIPINARRVPHI 151
               LQ  +V            E  +VG D   DLAVLKI   G  L  + +       +
Sbjct: 106 DQFGLQRCKVSLVDAKGTRFSKEGKIVGLDPDNDLAVLKIETEGRELNPVVLGTSNDLRV 165

Query: 152 GDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGR--QNFLQTDASINHGNSGGALVNSL 209
           G    AIGNPY    T+T G++S  GR   +P G+     +QTDA IN GN+GG L++S 
Sbjct: 166 GQSCFAIGNPYGYENTLTIGVVSGLGREIPSPNGKSISEAIQTDADINSGNAGGPLLDSY 225

Query: 210 GELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIR 256
           G  +G+NT +F +   G +  G+ FAIP     + +  LI  G   R
Sbjct: 226 GHTIGVNTATFTRKGSGMSS-GVNFAIPIDTVVRTVPYLIVYGTAYR 271


>5ILA-A nrPDB
          Length = 301

 Score =  186 bits (471), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 54/220 (24%), Positives = 91/220 (41%), Gaps = 20/220 (9%)

Query: 50  AVRRAAP---AVVNVYNRGLNTN----SHNQLEIRTLGSGVIMDQRGYIITNKHVINDAD 102
            V +  P   AVV V+      N       + +  +  SG I+  R  ++TN H +    
Sbjct: 91  TVVKVVPSMDAVVKVFCVHTEPNFSLPWQRKRQYSSGSSGFIIGGR-RVLTNAHSVEHHT 149

Query: 103 QIIVALQ-DGRVFEALLVGSDSLTDLAVLKINATGGLPTI-PINARRVPHIGDVVLAIGN 160
           Q+ +  +     + A ++   +  D+A+L +        + P+    +P + D V  +G 
Sbjct: 150 QVKLKKRGSDTKYLATVLAIGTECDIALLTVTDDEFWEGVSPVEFGDLPALQDAVTVVGY 209

Query: 161 PYNLGQ-TITQGIISATGRIGLNPTGRQNF-LQTDASINHGNSGGALVNSLGELMGINTL 218
           P      ++T G++S    +       +   LQ DA+IN GNSGG   N  G+ +GI   
Sbjct: 210 PIGGDTISVTSGVVSRMEILSYVHGSTELLGLQIDAAINSGNSGGPAFNDKGKCVGIAFQ 269

Query: 219 SFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGY 258
           S       E  E IG+ IP    T ++   I+D      Y
Sbjct: 270 SLKH----EDAENIGYVIP----TPVIVHFIQDYEKHDKY 301


>5HM9-A nrPDB
          Length = 189

 Score =  158 bits (399), Expect = 4e-39,   Method: Composition-based stats.
 Identities = 48/171 (28%), Positives = 78/171 (45%), Gaps = 9/171 (5%)

Query: 81  SGVIMDQRGYIITNKHVINDADQIIVALQDG---RVFEALLVGSDSLTDLAVLKINATGG 137
           SG I+   GY+IT  H ++   +I V +      R F A +V +    DLA+LK+  T  
Sbjct: 24  SGAIVGTNGYVITTLHSVSKLPEISVQVATTGGIRRFPAQVVKTIPGHDLALLKMQTTEK 83

Query: 138 LPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGII-SATGRIGLNPTGRQNFLQTDASI 196
                +   +    G  V A G        + QG++ SA   + +  T   + L++DA  
Sbjct: 84  FLHFRMADVQTVVPGQQVFAFGRNMAGAPLVRQGLVQSADAPLAVGATQITHLLRSDAVY 143

Query: 197 NHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDK 247
           +   +GG LVN+ G+L+GIN  +      G T +  GF +P Q+    +  
Sbjct: 144 SWEQTGGPLVNAQGDLVGINIAA-----TGPTGKVEGFTVPAQVIVSHLQD 189


>3LT3-A nrPDB
          Length = 217

 Score = 73.2 bits (178), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 53/212 (25%), Positives = 87/212 (41%), Gaps = 27/212 (12%)

Query: 48  NLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDADQIIVA 107
           N  V    P+VV +  R L       LE    G+G ++     ++TN HV+  ++ + V 
Sbjct: 14  NPVVAATEPSVVKI--RSLAPRCQKVLE----GTGFVISPD-RVMTNAHVVAGSNNVTVY 66

Query: 108 LQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVP-HIGDVVLAIGNPYNLGQ 166
             D + FEA +V  D   D+A+L   A   LP  P+     P   G  V+ +G P     
Sbjct: 67  AGD-KPFEATVVSYDPSVDVAIL---AVPHLPPPPLVFAAEPAKTGADVVVLGYPGGGNF 122

Query: 167 TITQG-IISATGRIGLNPTGRQNFLQTD-----ASINHGNSGGALVNSLGELMGINTLSF 220
           T T   I  A    G +  G    +  D     A +  G++GG L++  G+++G+     
Sbjct: 123 TATPARIREAIRLSGPDIYGDPEPVTRDVYTIRADVEQGDAGGPLIDLNGQVLGV----- 177

Query: 221 DKSNDGETPEGIGFAIPFQLATKIMDKLIRDG 252
                       GF +    A ++  +L + G
Sbjct: 178 -VFGAAIDDAETGFVL---TAGEVAGQLAKIG 205


>1DUE-A nrPDB
          Length = 242

 Score = 59.7 bits (143), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 36/202 (17%), Positives = 76/202 (37%), Gaps = 41/202 (20%)

Query: 74  LEIRTLGSGVIMDQRGYIITNKHV--INDADQIIVALQ-------DGRV------FEALL 118
           ++ +T  +GV++ +   ++TN+H+    + D   V+ +       +G        +E   
Sbjct: 51  VKGQTSATGVLIGKN-TVLTNRHIAKFANGDPSKVSFRPSINTDDNGNTETPYGEYEVKE 109

Query: 119 VGSDS---LTDLAVLKINAT-------GGLPTIPINARRVPHIGDVVLAIGNPYNLGQTI 168
           +  +      DLA++++            +    I        GD +  IG P++     
Sbjct: 110 ILQEPFGAGVDLALIRLKPDQNGVSLGDKISPAKIGTSNDLKDGDKLELIGYPFDHK--- 166

Query: 169 TQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGET 228
               ++   R  +  T     L+       GN+G  + NS GEL+GI++      +    
Sbjct: 167 ----VNQMHRSEIELTTLSRGLRYYGFTVPGNAGSGIFNSNGELVGIHSSKVSHLDREHQ 222

Query: 229 ---PEGIGFAIPFQLATKIMDK 247
                GIG         +I+++
Sbjct: 223 INYGVGIG-----NYVKRIINE 239


>4INK-A nrPDB
          Length = 205

 Score = 58.9 bits (141), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 38/196 (19%), Positives = 66/196 (33%), Gaps = 25/196 (12%)

Query: 57  AVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHV---------INDADQIIVA 107
           +V  + N  +   S   +     G+G ++     IITNKHV         I         
Sbjct: 5   SVKLITNTNVAPYS--GVTWMGAGTGFVVGNH-TIITNKHVTYHMKVGDEIKAHPNGFYN 61

Query: 108 LQDGRVFEALLVGSDSLTDLAVLKINATGGLP--------TIPINARRVPHIGDVVLAIG 159
              G      +V      D+AV+++      P        T   N        + +  IG
Sbjct: 62  NGGGLYKVTKIVDYPGKEDIAVVQVEEKSTQPKGRKFKDFTSKFNIASEAKENEPISVIG 121

Query: 160 NPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTLS 219
            P   G  +           G   +   N + +DA +  G+SG  ++NS  E +G+   S
Sbjct: 122 YPNPNGNKLQM-----YESTGKVLSVNGNIVTSDAVVQPGSSGSPILNSKREAIGVMYAS 176

Query: 220 FDKSNDGETPEGIGFA 235
              + +      + F+
Sbjct: 177 DKPTGESTRSFAVYFS 192


>2KL1-A nrPDB
          Length = 94

 Score = 57.4 bits (137), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 20/75 (26%), Positives = 41/75 (54%), Gaps = 1/75 (1%)

Query: 278 QLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMR 337
           + +G+ V  V P+ PAA   ++  D I ++D +P  ++ + +  V E + G  + V  +R
Sbjct: 3   EAKGVYVMSVLPNMPAA-GRLEAGDRIAAIDGQPINTSEQIVSYVREKQAGDRVRVTFIR 61

Query: 338 DDKQLTLQVTIQEYP 352
           D KQ   ++ ++ +P
Sbjct: 62  DRKQHEAELVLKPFP 76


>5MM8-A nrPDB
          Length = 204

 Score = 55.9 bits (133), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 38/189 (20%), Positives = 68/189 (35%), Gaps = 22/189 (11%)

Query: 63  NRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDAD--QIIVALQDGRVFEA---- 116
            +  N   +N +     G+G I+ +   I+TNKHV+   +    I+A  +G         
Sbjct: 9   IKNTNVAPYNGVVSIGSGTGFIVGKN-TIVTNKHVVAGMEIGAHIIAHPNGEYNNGGFYK 67

Query: 117 --LLVGSDSLTDLAVLKINATGGLPTIP--------INARRVPHIGDVVLAIGNPYNLGQ 166
              +V      D+A+L +      P           +         + +  +G P     
Sbjct: 68  VKKIVRYSGQEDIAILHVEDKAVHPKNRNFKDYTGILKIASEAKENERISIVGYPEPYIN 127

Query: 167 TITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDG 226
                        G   + + N + TDA +  GNSG A+ NS  E++G++       N  
Sbjct: 128 KFQM-----YESTGKVLSVKGNMIITDAFVEPGNSGSAVFNSKYEVVGVHFGGNGPGNKS 182

Query: 227 ETPEGIGFA 235
               G+ F+
Sbjct: 183 TKGYGVYFS 191


>2AS9-A nrPDB
          Length = 210

 Score = 53.5 bits (127), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 39/189 (20%), Positives = 64/189 (33%), Gaps = 28/189 (14%)

Query: 81  SGVIMDQRGYIITNKHVIND---ADQIIV----ALQDGRVFEALLVGSDS-LTDLAVLKI 132
           +G ++ +   IITNKHV  D    D+I         +G +++   +       D++V+ I
Sbjct: 26  TGFVIGKN-TIITNKHVSKDYKVGDRITAHPNGDKGNGGIYKIKSISDYPGDEDISVMNI 84

Query: 133 NATG----------GLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLN 182
                                N  +   + D +  IG P     +  Q         G  
Sbjct: 85  EEQAVERGPKGFNFNENVQAFNFAKDAKVDDKIKVIGYPLPAQNSFKQ-----FESTGTI 139

Query: 183 PTGRQNFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLAT 242
              + N L  DA I  GNSG  ++NS  E++G+      K           +  P     
Sbjct: 140 KRIKDNILNFDAYIEPGNSGSPVLNSNNEVIGVVYGGIGKIGSEYNGAV--YFTP--QIK 195

Query: 243 KIMDKLIRD 251
             + K I  
Sbjct: 196 DFIQKHIEQ 204


>4JCN-A nrPDB
          Length = 216

 Score = 52.4 bits (124), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 38/172 (22%), Positives = 63/172 (36%), Gaps = 26/172 (15%)

Query: 79  LGSGVIMDQRGYIITNKHVINDA----DQIIV---ALQDGRVFEALLVGSDS-----LTD 126
            GSGV++ +   I+TNKHV+N A      I V   A  +        VG +       +D
Sbjct: 35  SGSGVVVGEN-EILTNKHVVNGAKGNPRNISVHPSAKNENDYPNGKFVGQEIIPYPGNSD 93

Query: 127 LAVLKINATGG-------LPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRI 179
           LA+L+++           +    I++     I + +   G P       T         +
Sbjct: 94  LAILRVSPNEHNQHIGQVVKPATISSNTDTRINENITVTGYP-GDKPLATM-----WESV 147

Query: 180 GLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEG 231
           G         L+ D S   GNSG  + N   +++GI+    D   +      
Sbjct: 148 GKVVYIGGEELRYDLSTVGGNSGSPVFNGKNQVIGIHYGGVDNKYNSSVYIN 199


>2KJP-A nrPDB
          Length = 91

 Score = 51.2 bits (121), Expect = 7e-07,   Method: Composition-based stats.
 Identities = 21/72 (29%), Positives = 41/72 (56%), Gaps = 1/72 (1%)

Query: 281 GIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDDK 340
           GI  + V  + PA    I+V D IIS D K   SA + +D ++  + G  + + + R++K
Sbjct: 2   GIYASSVVENMPA-KGKIEVGDKIISADGKNYQSAEKLIDYISSKKAGDKVTLKIEREEK 60

Query: 341 QLTLQVTIQEYP 352
           +  + +T++++P
Sbjct: 61  EKRVTLTLKQFP 72


>4JJ3-A nrPDB
          Length = 243

 Score = 50.1 bits (118), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 23/156 (14%), Positives = 62/156 (39%), Gaps = 21/156 (13%)

Query: 202 GGALVNSLGELMGINTLSFDKSNDGETP------EGIGFAIPFQLATKIMDKLIRDGRVI 255
           G  +V   G+ MG+      +  +   P         GF  P           ++     
Sbjct: 19  GAPIVGGQGQAMGLPVAMQRRRGEQRAPVPALSDANGGFVAPN----------VQFSEAH 68

Query: 256 RGYIGIGGREIAPLHAQGGGID-QLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAIS 314
             + G+    ++    +   +   L+G++++E S +  AA +G+   D++++++ +   +
Sbjct: 69  --WQGMEALPLSIELKRKLKLPLDLEGLLIDETSLN--AAVSGLLAGDVLVAINGRKVKT 124

Query: 315 ALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQE 350
             +   +   ++      + V R  + LTL ++ ++
Sbjct: 125 LKKMQKETRRVQMDRRASLTVYRKGRLLTLTLSEEK 160


>1DT2-A nrPDB
          Length = 245

 Score = 49.7 bits (117), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 41/168 (24%), Positives = 59/168 (35%), Gaps = 37/168 (22%)

Query: 74  LEIRTLGSGVIMDQRGYIITNKHVINDADQ----IIVALQDGR------------VFEAL 117
           ++  TL +GV++ +   I+TN HV  +A +    II      R             FEA 
Sbjct: 43  VKGSTLATGVLIGKN-TIVTNYHVAREAAKNPSNIIFTPAQNRDAEKNEFPTPYGKFEAE 101

Query: 118 LVGSDS---LTDLAVLKINATGG-------LPTIPINARRVPHIGDVVLAIGNPYNLGQT 167
            +         DLA++K+            +    I        GD    +G PYN    
Sbjct: 102 EIKESPYGQGLDLAIIKLKPNEKGESAGDLIQPANIPDHIDIQKGDKYSLLGYPYNYS-- 159

Query: 168 ITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGI 215
                 S            Q F  T+     GNSG  + N  GEL+GI
Sbjct: 160 ----AYSLYQSQIEMFNDSQYFGYTEV----GNSGSGIFNLKGELIGI 199


>4QL6-A nrPDB
          Length = 634

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 20/73 (27%), Positives = 36/73 (49%), Gaps = 4/73 (5%)

Query: 277 DQLQGIVVNEVSPDGPAANAG-IQVNDLIISVDNKPAISALETMDQVAEIR--PGSVIPV 333
           + + G+VV EV   GPA   G ++V D+I  V+ K   +       +  +R  PGS + +
Sbjct: 245 EDIDGVVVKEVLAGGPADKTGSLRVGDIIYRVNGKNIEN-TPFPGVLDSLRGSPGSSVTL 303

Query: 334 VVMRDDKQLTLQV 346
            + R +    +Q+
Sbjct: 304 DIHRQNNDHVIQL 316


>2W7U-A nrPDB
          Length = 200

 Score = 48.5 bits (114), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 36/167 (21%), Positives = 57/167 (34%), Gaps = 41/167 (24%)

Query: 91  IITNKHVINDADQIIVAL--------QDGRVFEALLVGSDSLT-DLAVLKINAT------ 135
           I+TNKH+    D     +        + G  ++   +       DLA++ ++ T      
Sbjct: 34  IVTNKHIAKSNDIFKNRVSAHHSSKGKGGGNYDVKDIVEYPGKEDLAIVHVHETSTEGLN 93

Query: 136 --GGLPTIPINARRVPHIGDVVLAIGNPYN-------LGQTITQGIISATGRIGLNPTGR 186
               +              D +  IG P            T T   IS T          
Sbjct: 94  FNKNVSYTKFADGAKVK--DRISVIGYPKGAQTKYKMFESTGTINHISGT---------- 141

Query: 187 QNFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIG 233
             F++ DA    GNSG  ++NS  EL+GI    +  S   E+ +  G
Sbjct: 142 --FMEFDAYAQPGNSGSPVLNSKHELIGI---LYAGSGKDESEKNFG 183


>1WCZ-A nrPDB
          Length = 268

 Score = 48.2 bits (113), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 37/216 (17%), Positives = 70/216 (32%), Gaps = 36/216 (16%)

Query: 58  VVNVYNRGLNTNSHNQLEIRT---LGSGVIMDQRGYIITNKHVINDADQIIVALQ----- 109
           + +  N      ++ Q+E  T   + SGV++ +   ++TNKHV++       AL+     
Sbjct: 11  ITDTTNGHYAPVTYIQVEAPTGTFIASGVVVGKD-TLLTNKHVVDATHGDPHALKAFPSA 69

Query: 110 -------DGRVFEALLVGSDSLTDLAVLKINATGG-------LPTIPINARRVPHIGDVV 155
                  +G      +       DLA++K +           +    ++      +   +
Sbjct: 70  INQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNI 129

Query: 156 LAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGI 215
              G P       T          G     +   +Q D S   GNSG  + N   E++GI
Sbjct: 130 TVTGYP-GDKPVATM-----WESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGI 183

Query: 216 NTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRD 251
           +        +G                  + + I D
Sbjct: 184 HWGGVPNEFNGAVFINEN-------VRNFLKQNIED 212


>3I1E-A nrPDB
          Length = 90

 Score = 47.8 bits (112), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 16/71 (22%), Positives = 30/71 (42%), Gaps = 1/71 (1%)

Query: 279 LQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRD 338
           + G+ V  V  D PAA   +   DLI  +D +   S+ E +D +   + G  + +     
Sbjct: 1   MDGVYVLSVKEDVPAA-GILHAGDLITEIDGQSFKSSQEFIDYIHSKKVGDTVKIKYKHG 59

Query: 339 DKQLTLQVTIQ 349
           +K     + + 
Sbjct: 60  NKNEEASIKLT 70


>2KJK-A nrPDB
          Length = 100

 Score = 47.8 bits (112), Expect = 7e-06,   Method: Composition-based stats.
 Identities = 16/70 (22%), Positives = 29/70 (41%), Gaps = 1/70 (1%)

Query: 280 QGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDD 339
            G+ V  V  D PAA   +   DLI  +D +   S+ E +D +   + G  + +     +
Sbjct: 7   DGVYVLSVKEDVPAA-GILHAGDLITEIDGQSFKSSQEFIDYIHSKKVGDTVKIKYKHGN 65

Query: 340 KQLTLQVTIQ 349
           K     + + 
Sbjct: 66  KNEEASIKLT 75


>4K1S-A nrPDB
          Length = 206

 Score = 47.4 bits (111), Expect = 9e-06,   Method: Composition-based stats.
 Identities = 35/173 (20%), Positives = 64/173 (36%), Gaps = 24/173 (13%)

Query: 81  SGVIMDQRGYIITNKHVIND---ADQIIVALQDGR-----VFEALLVGSDSLTDLAVLKI 132
           +G ++ +   I+TNKHV  +    D+I       +          ++      D++V+++
Sbjct: 27  TGFVVGKN-TILTNKHVSKNYKVGDRITAHPNSDKGNGGIYSIKKIINYPGKEDVSVIQV 85

Query: 133 N------ATGGLP----TIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLN 182
                     G        P         G+ +  IG P+         +  +TG +   
Sbjct: 86  EERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHPYKNKYV--LYESTGPVMSV 143

Query: 183 PTGRQNFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFA 235
                 +    A    GNSG  ++NS  EL+GI+  S  K++D     G+ F 
Sbjct: 144 EGSSIVY---SAHTESGNSGSPVLNSNNELVGIHFASDVKNDDNRNAYGVYFT 193


>5C2Z-A nrPDB
          Length = 255

 Score = 45.8 bits (107), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 39/168 (23%), Positives = 67/168 (39%), Gaps = 35/168 (20%)

Query: 74  LEIRTLGSGVIMDQRGYIITNKHVI----NDADQIIVALQDGRVFEALLVGS-------- 121
           ++ +T+ +G+++ +   +ITNKH+     ND +++I      R   +L+V          
Sbjct: 51  VKGKTIATGILIGKN-TVITNKHIARLAENDPNKVIFTPGSTRDEGSLVVKKPFGEFIAE 109

Query: 122 -------DSLTDLAVLKINAT-------GGLPTIPINARRVPHIGDVVLAIGNPYNLGQT 167
                     TDL+++K+            +    I        GD +  +G PY    T
Sbjct: 110 EINEAPYGGGTDLSIIKLKPNQYGKSAGDLVTPAAIPDNVDVQKGDKISLLGYPY---NT 166

Query: 168 ITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGI 215
            T  +  +      N    Q F  T+     GNSG  + N  GEL+GI
Sbjct: 167 STHSLYKS-QIEVFNNQTFQYFAYTE----PGNSGSGIFNLHGELVGI 209


>3I18-A nrPDB
          Length = 100

 Score = 44.7 bits (104), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 17/70 (24%), Positives = 29/70 (41%), Gaps = 1/70 (1%)

Query: 280 QGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDD 339
            G+ V  V  D PAA+  +   DLI  +D     S+ E +D +   + G  + +     D
Sbjct: 7   DGVYVMSVKDDVPAADV-LHAGDLITEIDGNAFKSSQEFIDYIHSKKVGDTVKINYKHGD 65

Query: 340 KQLTLQVTIQ 349
           K     + + 
Sbjct: 66  KNEQADIKLT 75


>4FGM-A nrPDB
          Length = 597

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 1/71 (1%)

Query: 280 QGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDD 339
           QG+ V  V  D  A +AG+   D II++D+  A         +    PG  + +   R D
Sbjct: 496 QGLDVLNVYHDESAYHAGLSAGDKIIAIDHLQATEQS-VKRILERYIPGDTVTIHAFRRD 554

Query: 340 KQLTLQVTIQE 350
           + +TL++T QE
Sbjct: 555 ELMTLELTWQE 565


>5E6P-B nrPDB
          Length = 88

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 14/55 (25%), Positives = 28/55 (50%), Gaps = 1/55 (1%)

Query: 282 IVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVM 336
           ++V  V P G A  AG++  D II V+     ++    + V  I+ G+ + + ++
Sbjct: 30  VLVQSVRPGGAAMKAGVKEGDRIIKVNGTMVTNSSHL-EVVKLIKSGAYVALTLL 83


>2DLS-A nrPDB
          Length = 93

 Score = 43.1 bits (100), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 14/55 (25%), Positives = 28/55 (50%), Gaps = 1/55 (1%)

Query: 282 IVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVM 336
           ++V  V P G A  AG++  D II V+     ++    + V  I+ G+ + + ++
Sbjct: 31  VLVQSVRPGGAAMKAGVKEGDRIIKVNGTMVTNSSHL-EVVKLIKSGAYVALTLL 84


>4C2G-A nrPDB
          Length = 446

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 5/66 (7%)

Query: 291 GPAANAGIQVNDLIISVDNKPAISALETMDQVAEIR--PGSVIPVVVMRDD--KQLTLQV 346
            PA  AG++ ND IIS++ +      +    V +IR   GS + + + R    KQL+ ++
Sbjct: 92  SPAEKAGLKPNDEIISINGESMA-GKDLNHAVLKIRGKKGSSVSMKIQRPGTKKQLSFRI 150

Query: 347 TIQEYP 352
              E P
Sbjct: 151 KRAEIP 156


>4O06-A nrPDB
          Length = 106

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 17/70 (24%), Positives = 35/70 (50%), Gaps = 2/70 (2%)

Query: 282 IVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSV--IPVVVMRDD 339
             ++EV P  P+  A I+V+D +IS+ N  A +  +  +    +       +PV+++R+ 
Sbjct: 21  AFISEVVPGSPSDKADIKVDDKLISIGNVHAANHSKLQNIQMVVMKNEDRPLPVLLLREG 80

Query: 340 KQLTLQVTIQ 349
           + L   +T  
Sbjct: 81  QILKTSLTPS 90


>2XKX-A nrPDB
          Length = 721

 Score = 41.6 bits (96), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 18/82 (21%), Positives = 35/82 (42%), Gaps = 9/82 (10%)

Query: 254 VIRGYIGIGGREIAPLHAQGGGIDQLQGIVVNEVSPDGPAANAG-IQVNDLIISVDNKPA 312
           + RG  G+G            G +  +GI ++ +   GPA  +G ++  D I+SV+    
Sbjct: 313 IHRGSTGLGF--------NIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDL 364

Query: 313 ISALETMDQVAEIRPGSVIPVV 334
            +A      +A    G  + ++
Sbjct: 365 RNASHEQAAIALKNAGQTVTII 386



 Score = 35.8 bits (81), Expect = 0.029,   Method: Composition-based stats.
 Identities = 19/84 (22%), Positives = 32/84 (38%), Gaps = 1/84 (1%)

Query: 272 QGGGIDQLQGIVVNEVSPDGPAANAG-IQVNDLIISVDNKPAISALETMDQVAEIRPGSV 330
               I     I + ++ P G AA  G ++VND I+ V+         +    A    GS+
Sbjct: 81  DNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSI 140

Query: 331 IPVVVMRDDKQLTLQVTIQEYPAT 354
           + + VMR        + I+     
Sbjct: 141 VRLYVMRRKPPAEKVMEIKLIKGP 164


>2EAQ-A nrPDB
          Length = 90

 Score = 41.2 bits (95), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 17/65 (26%), Positives = 31/65 (47%), Gaps = 2/65 (3%)

Query: 278 QLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAI--SALETMDQVAEIRPGSVIPVVV 335
            + GI V  V    PA  + +QV+D II+++N       + E  + +A+ +    + + V
Sbjct: 26  DIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDV 85

Query: 336 MRDDK 340
            R  K
Sbjct: 86  RRYGK 90


>2PKT-A nrPDB
          Length = 91

 Score = 41.2 bits (95), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 16/71 (22%), Positives = 31/71 (43%)

Query: 274 GGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPV 333
           GG D  Q + ++ V+P   AA A + + D+I ++D +   +      Q         + +
Sbjct: 21  GGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSNMTHLEAQNRIKGCTDNLTL 80

Query: 334 VVMRDDKQLTL 344
            V R + +  L
Sbjct: 81  TVARSEHESDL 91


>2HLC-A nrPDB
          Length = 230

 Score = 40.1 bits (92), Expect = 0.001,   Method: Composition-based stats.
 Identities = 41/204 (20%), Positives = 80/204 (39%), Gaps = 34/204 (16%)

Query: 62  YNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDADQIIVALQDGRVFEALLVGS 121
           Y  GL+    +Q  +   GS  ++D + +I+T  H ++DA  ++V L     +E   V +
Sbjct: 14  YQAGLDITLQDQRRVWCGGS--LIDNK-WILTAAHCVHDAVSVVVYLGSAVQYEGEAVVN 70

Query: 122 DSL-------------TDLAVLKI---NATGGLPTIPINARRVPHIG-DVVLAIGNPYNL 164
                            D+A++KI     T  +  I + +    +   + + A  + +  
Sbjct: 71  SERIISHSMFNPDTYLNDVALIKIPHVEYTDNIQPIRLPSGEELNNKFENIWATVSGWGQ 130

Query: 165 GQTITQGIISATGRIGLNPTGRQNF---LQTDASI----------NHGNSGGALVNSLGE 211
             T T  +      +  N    Q +   +  +++I            G+SGG  V S   
Sbjct: 131 SNTDTVILQYTYNLVIDNDRCAQEYPPGIIVESTICGDTSDGKSPCFGDSGGPFVLSDKN 190

Query: 212 LMGINTLSFDKSNDGETPEGIGFA 235
           L+ I  +SF      E+ + +GF+
Sbjct: 191 LL-IGVVSFVSGAGCESGKPVGFS 213


>1UEZ-A nrPDB
          Length = 101

 Score = 39.7 bits (91), Expect = 0.002,   Method: Composition-based stats.
 Identities = 20/73 (27%), Positives = 30/73 (41%), Gaps = 12/73 (16%)

Query: 274 GGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPV 333
           GG +   GI V+ V P   A   G++V D I+ V++K               R      V
Sbjct: 29  GGSEHGVGIYVSLVEPGSLAEKEGLRVGDQILRVNDKSLA------------RVTHAEAV 76

Query: 334 VVMRDDKQLTLQV 346
             ++  K+L L V
Sbjct: 77  KALKGSKKLVLSV 89


>1FC9-A nrPDB
          Length = 388

 Score = 39.3 bits (90), Expect = 0.003,   Method: Composition-based stats.
 Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)

Query: 282 IVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVM 336
           +VV   +P GPA  AG +  D+I++VD       L   D    ++  +   V V+
Sbjct: 101 VVVLTPAPGGPAEKAGARAGDVIVTVDGTAVK-GLSLYDVSDLLQGEADSQVEVV 154


>2V90-A nrPDB
          Length = 96

 Score = 39.3 bits (90), Expect = 0.003,   Method: Composition-based stats.
 Identities = 18/78 (23%), Positives = 30/78 (38%)

Query: 269 LHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPG 328
           L  +  G+D   G  + EV P  PA  AG+Q  D +++V  +                 G
Sbjct: 19  LLREEKGLDGRPGQFLWEVDPGLPAKKAGMQAGDRLVAVAGESVEGLGHEETVSRIQGQG 78

Query: 329 SVIPVVVMRDDKQLTLQV 346
           S + + V+  +      V
Sbjct: 79  SCVSLTVVDPEADRETSV 96


>2L4S-A nrPDB
          Length = 124

 Score = 38.5 bits (88), Expect = 0.004,   Method: Composition-based stats.
 Identities = 25/79 (31%), Positives = 37/79 (46%), Gaps = 5/79 (6%)

Query: 236 IPFQLATKIMDKLI----RDGR-VIRGYIGIGGREIAPLHAQGGGIDQLQGIVVNEVSPD 290
           IP Q  T ++ ++     R G  +I G+   GG +  P           +GI V  VS  
Sbjct: 4   IPGQPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEG 63

Query: 291 GPAANAGIQVNDLIISVDN 309
           GPA  AG+Q+ D I+ V+ 
Sbjct: 64  GPAEIAGLQIGDKIMQVNG 82


>2VZ5-A nrPDB
          Length = 139

 Score = 38.1 bits (87), Expect = 0.006,   Method: Composition-based stats.
 Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 1/72 (1%)

Query: 239 QLATKIMDKLIRDGR-VIRGYIGIGGREIAPLHAQGGGIDQLQGIVVNEVSPDGPAANAG 297
            +  ++    +R G  +I G+   GG +  P           +GI V  VS  GPA  AG
Sbjct: 22  SMVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG 81

Query: 298 IQVNDLIISVDN 309
           +Q+ D I+ V+ 
Sbjct: 82  LQIGDKIMQVNG 93


>2QBW-A nrPDB
          Length = 195

 Score = 37.8 bits (86), Expect = 0.007,   Method: Composition-based stats.
 Identities = 14/68 (20%), Positives = 26/68 (38%), Gaps = 1/68 (1%)

Query: 271 AQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSV 330
                     GI V  V P+GPA+   +Q  D II  +    I+              + 
Sbjct: 15  RGNPFRPDDDGIFVTRVQPEGPASKL-LQPGDKIIQANGYSFINIEHGQAVSLLKTFQNT 73

Query: 331 IPVVVMRD 338
           + ++++R+
Sbjct: 74  VELIIVRE 81


>3K1R-A nrPDB
          Length = 192

 Score = 37.8 bits (86), Expect = 0.007,   Method: Composition-based stats.
 Identities = 12/56 (21%), Positives = 25/56 (44%), Gaps = 1/56 (1%)

Query: 281 GIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVM 336
           G+ ++ +   G A + G+QV D I+ ++     S     + +  IR    + + V 
Sbjct: 111 GLFISHLIKGGQADSVGLQVGDEIVRINGYSISSCTH-EEVINLIRTEKTVSIKVR 165


>3CH8-A nrPDB
          Length = 195

 Score = 37.8 bits (86), Expect = 0.007,   Method: Composition-based stats.
 Identities = 14/68 (20%), Positives = 26/68 (38%), Gaps = 1/68 (1%)

Query: 271 AQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSV 330
                     GI V  V P+GPA+   +Q  D II  +    I+              + 
Sbjct: 16  RGNPFRPDDDGIFVTRVQPEGPASKL-LQPGDKIIQANGYSFINIEHGQAVSLLKTFQNT 74

Query: 331 IPVVVMRD 338
           + ++++R+
Sbjct: 75  VELIIVRE 82


>3TSW-A nrPDB
          Length = 391

 Score = 37.4 bits (85), Expect = 0.009,   Method: Composition-based stats.
 Identities = 15/55 (27%), Positives = 26/55 (47%), Gaps = 2/55 (3%)

Query: 281 GIVVNEVSPDGPAANAGIQVNDLIISVDNKPAIS--ALETMDQVAEIRPGSVIPV 333
           GI V  V  D PAA  G++  D I+ V+N    +    E +  + ++  G  + +
Sbjct: 32  GIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIREEAVLFLLDLPKGEEVTI 86


>3SHW-A nrPDB
          Length = 468

 Score = 37.4 bits (85), Expect = 0.009,   Method: Composition-based stats.
 Identities = 15/55 (27%), Positives = 26/55 (47%), Gaps = 2/55 (3%)

Query: 281 GIVVNEVSPDGPAANAGIQVNDLIISVDNKPAIS--ALETMDQVAEIRPGSVIPV 333
           GI V  V  D PAA  G++  D I+ V+N    +    E +  + ++  G  + +
Sbjct: 24  GIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIREEAVLFLLDLPKGEEVTI 78


>1MFG-A nrPDB
          Length = 95

 Score = 37.0 bits (84), Expect = 0.012,   Method: Composition-based stats.
 Identities = 14/68 (20%), Positives = 26/68 (38%), Gaps = 1/68 (1%)

Query: 271 AQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSV 330
                     GI V  V P+GPA+   +Q  D II  +    I+              + 
Sbjct: 26  RGNPFRPDDDGIFVTRVQPEGPASKL-LQPGDKIIQANGYSFINIEHGQAVSLLKTFQNT 84

Query: 331 IPVVVMRD 338
           + ++++R+
Sbjct: 85  VELIIVRE 92


>1M5Z-A nrPDB
          Length = 91

 Score = 37.0 bits (84), Expect = 0.014,   Method: Composition-based stats.
 Identities = 11/59 (18%), Positives = 26/59 (44%)

Query: 280 QGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRD 338
           +G+ V  + P GP    G++  D ++ V++         +        G+ + +V+ R+
Sbjct: 32  KGVYVKNIRPAGPGDLGGLKPYDRLLQVNHVRTRDFDCCLVVPLIAESGNKLDLVISRN 90


>3CYY-A nrPDB
          Length = 92

 Score = 36.6 bits (83), Expect = 0.015,   Method: Composition-based stats.
 Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 1/66 (1%)

Query: 282 IVVNEVSPDGPAAN-AGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDDK 340
           I V E+S D  AA    IQ  D+++ ++     +   T  +    R    + +VV RD++
Sbjct: 25  IFVKEISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKMVVQRDER 84

Query: 341 QLTLQV 346
              L V
Sbjct: 85  ATLLNV 90


>4Q2Q-A nrPDB
          Length = 102

 Score = 36.6 bits (83), Expect = 0.015,   Method: Composition-based stats.
 Identities = 15/55 (27%), Positives = 26/55 (47%), Gaps = 2/55 (3%)

Query: 281 GIVVNEVSPDGPAANAGIQVNDLIISVDNKPAIS--ALETMDQVAEIRPGSVIPV 333
           GI V  V  D PAA  G++  D I+ V+N    +    E +  + ++  G  + +
Sbjct: 30  GIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIREEAVLFLLDLPKGEEVTI 84


>5G1D-A nrPDB
          Length = 201

 Score = 36.6 bits (83), Expect = 0.015,   Method: Composition-based stats.
 Identities = 14/69 (20%), Positives = 31/69 (44%), Gaps = 3/69 (4%)

Query: 281 GIVVNEVSPDGPAANAGIQVNDLIISVDNKPAIS-ALETMDQVAEIRPGSVIPVVVMRDD 339
           GI V  V  + PA+  G++  D ++ ++ +     + +   +V +   G  I + +   D
Sbjct: 38  GIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIR--D 95

Query: 340 KQLTLQVTI 348
           +     VT+
Sbjct: 96  RPFERTVTM 104


>2KBS-A nrPDB
          Length = 92

 Score = 36.6 bits (83), Expect = 0.017,   Method: Composition-based stats.
 Identities = 12/59 (20%), Positives = 29/59 (49%), Gaps = 1/59 (1%)

Query: 278 QLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVM 336
           Q  GI ++ V P   +A  G+++ D I+ V+     + L+  + V  ++    + + ++
Sbjct: 25  QKPGIFISHVKPGSLSAEVGLEIGDQIVEVNGVDFSN-LDHKEAVNVLKSSRSLTISIV 82


>5N7D-A nrPDB
          Length = 427

 Score = 36.6 bits (83), Expect = 0.017,   Method: Composition-based stats.
 Identities = 21/105 (20%), Positives = 42/105 (40%), Gaps = 15/105 (14%)

Query: 237 PFQLATKIMDKLIRDGRVIRGYIGIGGREIAPLHAQGGGIDQLQGIVVNEVSPDGPAANA 296
           P +L  K +   +R      G+  +GG E                  +  +  DGPAA  
Sbjct: 12  PSELKGKFIHTKLRKSSRGFGFTVVGGDEPDEFLQ------------IKSLVLDGPAALD 59

Query: 297 G-IQVNDLIISVDNKPAI--SALETMDQVAEIRPGSVIPVVVMRD 338
           G ++  D+I+SV++   +  +  + +     I  G+ + + + R 
Sbjct: 60  GKMETGDVIVSVNDTCVLGHTHAQVVKIFQSIPIGASVDLELCRG 104


>5A2P-A nrPDB
          Length = 163

 Score = 36.6 bits (83), Expect = 0.018,   Method: Composition-based stats.
 Identities = 14/69 (20%), Positives = 31/69 (44%), Gaps = 3/69 (4%)

Query: 281 GIVVNEVSPDGPAANAGIQVNDLIISVDNKPAIS-ALETMDQVAEIRPGSVIPVVVMRDD 339
           GI V  V  + PA+  G++  D ++ ++ +     + +   +V +   G  I + +   D
Sbjct: 26  GIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIR--D 83

Query: 340 KQLTLQVTI 348
           +     VT+
Sbjct: 84  RPFERTVTM 92


>1X5N-A nrPDB
          Length = 114

 Score = 36.2 bits (82), Expect = 0.020,   Method: Composition-based stats.
 Identities = 12/59 (20%), Positives = 29/59 (49%), Gaps = 1/59 (1%)

Query: 278 QLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVM 336
           Q  GI ++ V P   +A  G+++ D I+ V+     + L+  + V  ++    + + ++
Sbjct: 39  QKPGIFISHVKPGSLSAEVGLEIGDQIVEVNGVDFSN-LDHKEAVNVLKSSRSLTISIV 96


>5ZDS-A nrPDB
          Length = 96

 Score = 36.2 bits (82), Expect = 0.022,   Method: Composition-based stats.
 Identities = 18/60 (30%), Positives = 23/60 (38%), Gaps = 1/60 (1%)

Query: 281 GIVVNEVSPDGPAANAG-IQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDD 339
           GI V  + P GPAA  G I   D ++ VD                  PG V  +V+ R  
Sbjct: 37  GIYVKSIIPGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQCLKGPGQVARLVLERRG 96


>3TSV-A nrPDB
          Length = 124

 Score = 36.2 bits (82), Expect = 0.024,   Method: Composition-based stats.
 Identities = 15/55 (27%), Positives = 26/55 (47%), Gaps = 2/55 (3%)

Query: 281 GIVVNEVSPDGPAANAGIQVNDLIISVDNKPAIS--ALETMDQVAEIRPGSVIPV 333
           GI V  V  D PAA  G++  D I+ V+N    +    E +  + ++  G  + +
Sbjct: 52  GIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIREEAVLFLLDLPKGEEVTI 106


>1UEQ-A nrPDB
          Length = 123

 Score = 35.8 bits (81), Expect = 0.028,   Method: Composition-based stats.
 Identities = 14/58 (24%), Positives = 28/58 (48%), Gaps = 3/58 (5%)

Query: 284 VNEVSPDGPAANAG-IQVNDLIISVDNKPAI--SALETMDQVAEIRPGSVIPVVVMRD 338
           V  V PDGPAA  G ++  D+I+ ++    +  +  + +     +  G  + +V+ R 
Sbjct: 48  VKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVPIGQSVNLVLCRG 105


>1UF1-A nrPDB
          Length = 128

 Score = 35.4 bits (80), Expect = 0.035,   Method: Composition-based stats.
 Identities = 10/34 (29%), Positives = 19/34 (55%)

Query: 281 GIVVNEVSPDGPAANAGIQVNDLIISVDNKPAIS 314
           GI +  V P   A  +G++V D I+ V+ +  ++
Sbjct: 47  GIYITGVDPGSEAEGSGLKVGDQILEVNGRSFLN 80


>4XZY-A nrPDB
          Length = 720

 Score = 35.4 bits (80), Expect = 0.038,   Method: Composition-based stats.
 Identities = 10/19 (52%), Positives = 15/19 (78%)

Query: 199 GNSGGALVNSLGELMGINT 217
           GNSG  ++N+ GEL+G+N 
Sbjct: 653 GNSGSPVMNANGELIGLNF 671


>3SHU-A nrPDB
          Length = 95

 Score = 35.1 bits (79), Expect = 0.043,   Method: Composition-based stats.
 Identities = 15/55 (27%), Positives = 26/55 (47%), Gaps = 2/55 (3%)

Query: 281 GIVVNEVSPDGPAANAGIQVNDLIISVDNKPAIS--ALETMDQVAEIRPGSVIPV 333
           GI V  V  D PAA  G++  D I+ V+N    +    E +  + ++  G  + +
Sbjct: 27  GIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIREEAVLFLLDLPKGEEVTI 81


>1NPM-A nrPDB
          Length = 225

 Score = 35.1 bits (79), Expect = 0.045,   Method: Composition-based stats.
 Identities = 36/182 (19%), Positives = 60/182 (32%), Gaps = 36/182 (19%)

Query: 82  GVIMDQRGYIITNKHVINDADQIIV-----ALQDGRVFEALLVGS------------DSL 124
           GV++  R +++T  H       + +       +D    E  +  S            D  
Sbjct: 28  GVLVGDR-WVLTAAHCKKQKYSVRLGDHSLQSRDQPEQEIQVAQSIQHPCYNNSNPEDHS 86

Query: 125 TDLAVLKINATGGL--PTIPINARRV-PHIGDVVLAIG-----NPY-NLGQTIT---QGI 172
            D+ ++++  +  L     P+    + P +G   +  G     +P  N   T+      I
Sbjct: 87  HDIMLIRLQNSANLGDKVKPVQLANLCPKVGQKCIISGWGTVTSPQENFPNTLNCAEVKI 146

Query: 173 ISATGRIGLNPTGRQNFLQTDASIN-----HGNSGGALVNSLGELMGINTLSFDKSNDGE 227
            S        P      +    S N      G+SGG LV   G L GI +   D     E
Sbjct: 147 YSQNKCERAYPGKITEGMVCAGSSNGADTCQGDSGGPLV-CDGMLQGITSWGSDPCGKPE 205

Query: 228 TP 229
            P
Sbjct: 206 KP 207


>3BPU-A nrPDB
          Length = 88

 Score = 35.1 bits (79), Expect = 0.051,   Method: Composition-based stats.
 Identities = 16/62 (25%), Positives = 31/62 (50%), Gaps = 4/62 (6%)

Query: 281 GIVVNEVSPDGPAANAGIQVNDLIISVDNKPAI--SALETMDQVAEIRPGSVIPVVVMRD 338
           G  V ++  D P +  G++  DLI+ V+ K     +  + +D + E   GS + ++V R 
Sbjct: 28  GQRVKQIV-DSPRSR-GLKEGDLIVEVNKKNVQALTHNQVVDMLVESPKGSEVTLLVQRQ 85

Query: 339 DK 340
            +
Sbjct: 86  TR 87


>2LOB-A nrPDB
          Length = 112

 Score = 34.7 bits (78), Expect = 0.059,   Method: Composition-based stats.
 Identities = 14/56 (25%), Positives = 27/56 (48%), Gaps = 3/56 (5%)

Query: 274 GGIDQLQGIVVNEVSPDGPAAN-AGIQVNDLIISVDNKPAISA--LETMDQVAEIR 326
           GG +    I+++E+ P  PA    G+ V D I++V+          E +  +++ R
Sbjct: 47  GGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDTKHKEAVTILSQQR 102


>5JXF-A nrPDB
          Length = 731

 Score = 34.3 bits (77), Expect = 0.073,   Method: Composition-based stats.
 Identities = 9/19 (47%), Positives = 13/19 (68%)

Query: 199 GNSGGALVNSLGELMGINT 217
           GNSG   V++ G L+G+N 
Sbjct: 660 GNSGSPAVDAQGNLIGLNF 678


>5JWG-A nrPDB
          Length = 703

 Score = 34.3 bits (77), Expect = 0.078,   Method: Composition-based stats.
 Identities = 9/19 (47%), Positives = 15/19 (78%)

Query: 199 GNSGGALVNSLGELMGINT 217
           GN+G  ++N+ GEL+G+N 
Sbjct: 630 GNAGSPVMNARGELIGLNF 648


>3K50-A nrPDB
          Length = 403

 Score = 34.3 bits (77), Expect = 0.079,   Method: Composition-based stats.
 Identities = 13/59 (22%), Positives = 25/59 (42%), Gaps = 5/59 (8%)

Query: 277 DQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVV 335
           D     +++ V P  PA  AG+Q    I+ ++       +E     +E+  GS   + +
Sbjct: 87  DTAYNALISYVVPGSPAEEAGLQRGHWIMMMNGDYITKKVE-----SELLQGSTRQLQI 140


>2RCZ-A nrPDB
          Length = 81

 Score = 34.3 bits (77), Expect = 0.085,   Method: Composition-based stats.
 Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 1/58 (1%)

Query: 282 IVVNEVSPDGPAAN-AGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRD 338
           I V E+S D  AA    IQ  D+++ ++     +   T  +    R    + +VV RD
Sbjct: 23  IFVKEISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKMVVQRD 80


>2DC2-A nrPDB
          Length = 103

 Score = 33.9 bits (76), Expect = 0.11,   Method: Composition-based stats.
 Identities = 12/43 (27%), Positives = 21/43 (48%), Gaps = 1/43 (2%)

Query: 274 GGIDQLQGIVVNEVSPDGPAAN-AGIQVNDLIISVDNKPAISA 315
           GG +    I+++E+ P  PA    G+ V D I++V+       
Sbjct: 29  GGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDT 71


>2R4H-A nrPDB
          Length = 112

 Score = 33.9 bits (76), Expect = 0.11,   Method: Composition-based stats.
 Identities = 12/66 (18%), Positives = 29/66 (43%), Gaps = 1/66 (1%)

Query: 274 GGIDQLQGIVVNEVSPDGPAANAG-IQVNDLIISVDNKPAISALETMDQVAEIRPGSVIP 332
           GG +    + V  ++ DGPA  +G +++ D I+ ++ +   +   +         G  + 
Sbjct: 43  GGREYNMDLYVLRLAEDGPAERSGKMRIGDEILEINGETTKNMKHSRAIELIKNGGRRVR 102

Query: 333 VVVMRD 338
           + + R 
Sbjct: 103 LFLKRG 108


>3WOM-A nrPDB
          Length = 698

 Score = 33.9 bits (76), Expect = 0.11,   Method: Composition-based stats.
 Identities = 15/42 (35%), Positives = 24/42 (57%), Gaps = 4/42 (9%)

Query: 176 TGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINT 217
             RIG  P    N+L +D  I  GNSG  ++++ G+L+G+  
Sbjct: 612 DKRIGSVP---VNYL-SDLDITGGNSGSPVLDAHGKLVGLAF 649


>4JOF-A nrPDB
          Length = 87

 Score = 33.9 bits (76), Expect = 0.12,   Method: Composition-based stats.
 Identities = 12/43 (27%), Positives = 21/43 (48%), Gaps = 1/43 (2%)

Query: 274 GGIDQLQGIVVNEVSPDGPAAN-AGIQVNDLIISVDNKPAISA 315
           GG +    I+++E+ P  PA    G+ V D I++V+       
Sbjct: 22  GGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDT 64


>3G8Q-A nrPDB
          Length = 278

 Score = 33.5 bits (75), Expect = 0.13,   Method: Composition-based stats.
 Identities = 17/95 (17%), Positives = 35/95 (36%), Gaps = 15/95 (15%)

Query: 273 GGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGS--- 329
           G       G+ V EV PD P     +   D++++    P ++  +   +V  +  G    
Sbjct: 92  GPYYLARSGVEVVEVHPDEPLGYDPVDRLDVLLTFGGNPYLTEEDVAARVYCLLTGRGFD 151

Query: 330 ------------VIPVVVMRDDKQLTLQVTIQEYP 352
                        + ++V R D    +++  +E P
Sbjct: 152 ADIAPAPENLSGRVEIMVTRGDPDEAVELLKEELP 186


>3SOE-A nrPDB
          Length = 113

 Score = 33.5 bits (75), Expect = 0.14,   Method: Composition-based stats.
 Identities = 7/47 (14%), Positives = 24/47 (51%), Gaps = 2/47 (4%)

Query: 297 GIQVNDLIISVDNKPAISAL--ETMDQVAEIRPGSVIPVVVMRDDKQ 341
           G+Q  D+I  + ++   +    + ++ + +   G+ +P++++R    
Sbjct: 49  GLQKGDIIKEIYHQNVQNLTHLQVVEVLKQFPVGADVPLLILRGGPP 95


>5HJ1-A nrPDB
          Length = 103

 Score = 33.5 bits (75), Expect = 0.15,   Method: Composition-based stats.
 Identities = 11/68 (16%), Positives = 30/68 (44%), Gaps = 3/68 (4%)

Query: 286 EVSPDGPAA---NAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDDKQL 342
            ++P   A+    +G+Q NDL I+++        +    +  +   + I + V R+ ++ 
Sbjct: 35  RLNPGKDASLFRQSGLQANDLAIALNGIDLRDQEQAQQALQNLADMTEITLTVEREGQRH 94

Query: 343 TLQVTIQE 350
            +   + +
Sbjct: 95  DIAFALGD 102


>2LC7-A nrPDB
          Length = 102

 Score = 33.5 bits (75), Expect = 0.16,   Method: Composition-based stats.
 Identities = 19/78 (24%), Positives = 40/78 (51%), Gaps = 3/78 (3%)

Query: 259 IGIGGREIAPLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQ-VNDLIISVDNKPAISALE 317
           +G   R+   +     G+++  GI ++ + P G A + G+  VND +I V+      A +
Sbjct: 19  LGFYIRDGTSVRVTASGLEKQPGIFISRLVPGGLAESTGLLAVNDEVIEVNGIEV--AGK 76

Query: 318 TMDQVAEIRPGSVIPVVV 335
           T+DQV ++   +   +++
Sbjct: 77  TLDQVTDMMVANSSNLII 94


>3H7F-A nrPDB
          Length = 447

 Score = 33.1 bits (74), Expect = 0.18,   Method: Composition-based stats.
 Identities = 44/273 (16%), Positives = 89/273 (32%), Gaps = 44/273 (16%)

Query: 110 DGRVFEALLVGSDSLT---DLAVLKINATGGLPTIPI-NARRVPHIGDVV---------- 155
            G+++E    G D  T   D+  ++  A    P + I      P + D            
Sbjct: 154 SGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDFAAFRSIADEVG 213

Query: 156 -------------LAIG---NPYNLGQTITQGIISATG--RIGLNPTGRQNFLQTDASIN 197
                        +A G   +P      ++  +    G  R GL    +Q     ++++ 
Sbjct: 214 AKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQQYAKAINSAVF 273

Query: 198 HGNSGGALVN-SLGELMGINTLSFDKSNDGETPEGIGFAIPFQL-----ATKIMDKLIRD 251
            G  GG L++   G+ + +   +  +  D +     G  I           K    ++  
Sbjct: 274 PGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPDVAKAGVSVVSG 333

Query: 252 GRVIRGYIGIGGREIAPLHAQGGGIDQLQGIVVNEVS----PDGPAANAGIQVNDLIISV 307
           G  +   + +  R+          +    GI VN  +    P  P   +G+++    ++ 
Sbjct: 334 GTDVHLVL-VDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSGLRIGTPALAT 392

Query: 308 DNKPAISALETMDQVAE-IRPGSVIPVVVMRDD 339
                    E  D +A  +  GS + V  ++D 
Sbjct: 393 RGFGDTEFTEVADIIATALATGSSVDVSALKDR 425


>1RY4-A nrPDB
          Length = 128

 Score = 33.1 bits (74), Expect = 0.19,   Method: Composition-based stats.
 Identities = 20/101 (19%), Positives = 45/101 (44%), Gaps = 3/101 (2%)

Query: 236 IPFQLATKIMDKLIRDGRVIRGYIGIGGREIAPLHAQGGGIDQLQGIVVNEVSPDGPAAN 295
           I   +  +   ++          +G   R+   +     G+++  GI ++ + P G A +
Sbjct: 22  IDVDIVPETHRRVRLLKHGSDKPLGFYIRDGTSVRVTASGLEKQPGIFISRLVPGGLAES 81

Query: 296 AGIQ-VNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVV 335
            G+  VND +I V+      A +T+DQV ++   +   +++
Sbjct: 82  TGLLAVNDEVIEVNGIEV--AGKTLDQVTDMMVANSSNLII 120


>3QDO-A nrPDB
          Length = 109

 Score = 33.1 bits (74), Expect = 0.19,   Method: Composition-based stats.
 Identities = 15/47 (31%), Positives = 20/47 (42%), Gaps = 1/47 (2%)

Query: 284 VNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSV 330
           V+ V P G A  AG++  D I+ V+      A      V  IR G  
Sbjct: 47  VSAVLPGGAADRAGVRKGDRILEVNGVNVEGATH-KQVVDLIRAGEK 92


>2QT5-A nrPDB
          Length = 200

 Score = 33.1 bits (74), Expect = 0.20,   Method: Composition-based stats.
 Identities = 26/134 (19%), Positives = 51/134 (38%), Gaps = 11/134 (8%)

Query: 214 GINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREIAP---LH 270
           GIN   F         + +G  +  ++  ++    I+   V+   + +   +        
Sbjct: 63  GINLAKFRHDEIISLLKNVGERVVLEVEYELPPVSIQGSSVMFRTVEVTLHKEGNTFGFV 122

Query: 271 AQGGGIDQL---QGIVVNEVSPDGPAANAG-IQVNDLIISVDNKPA--ISALETMDQVAE 324
            +GG  D     + +V+  V P GPA   G I+  D ++SVD       +  E M  + +
Sbjct: 123 IRGGAHDDRNKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQ 182

Query: 325 IRPGSVIPVVVMRD 338
              G    +++  D
Sbjct: 183 C--GQEATLLIEYD 194


>3WYB-A nrPDB
          Length = 334

 Score = 32.7 bits (73), Expect = 0.23,   Method: Composition-based stats.
 Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 7/92 (7%)

Query: 112 RVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGNPYNL-GQTITQ 170
             F+A+   ++    +A++ +    G      +  R+   G+VVL +GN Y   G+ ++Q
Sbjct: 101 DYFDAVNAAAEQSGKVAIISV----GWDPGLFSLNRLL--GEVVLPVGNTYTFWGKGVSQ 154

Query: 171 GIISATGRIGLNPTGRQNFLQTDASINHGNSG 202
           G   A  RI       Q  +  D ++N   SG
Sbjct: 155 GHSDAIRRIQGVKNAVQYTIPIDEAVNRVRSG 186


>2D8I-A nrPDB
          Length = 114

 Score = 32.7 bits (73), Expect = 0.23,   Method: Composition-based stats.
 Identities = 13/59 (22%), Positives = 28/59 (47%), Gaps = 2/59 (3%)

Query: 272 QGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAI--SALETMDQVAEIRPG 328
                D ++ + VN V   G A+  G++  D I+ ++N+ A   ++    D +++   G
Sbjct: 36  SSVEEDGIRRLYVNSVKETGLASKKGLKAGDEILEINNRAADALNSSMLKDFLSQPSLG 94


>1NF3-C nrPDB
          Length = 128

 Score = 32.4 bits (72), Expect = 0.31,   Method: Composition-based stats.
 Identities = 19/97 (19%), Positives = 41/97 (42%), Gaps = 4/97 (4%)

Query: 242 TKIMDKLIRDGRVIRGYIGIGGREIAPLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQ-V 300
           T    +L + G      +G   R+ + +     G++++ GI ++ + P G A + G+  V
Sbjct: 29  THRRVRLCKYG--TEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAV 86

Query: 301 NDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMR 337
           ND ++ V+     S          +   S   ++ +R
Sbjct: 87  NDEVLEVNGIEV-SGKSLDQVTDMMIANSRNLIITVR 122


>1UJV-A nrPDB
          Length = 96

 Score = 32.4 bits (72), Expect = 0.31,   Method: Composition-based stats.
 Identities = 9/47 (19%), Positives = 21/47 (44%), Gaps = 2/47 (4%)

Query: 297 GIQVNDLIISVDNKPAISAL--ETMDQVAEIRPGSVIPVVVMRDDKQ 341
           G+   DLI+ ++ +   +    E +D + +   GS   +++ R    
Sbjct: 47  GLCEGDLIVEINQQNVQNLSHTEVVDILKDCPIGSETSLIIHRGSGP 93


>2JIL-A nrPDB
          Length = 97

 Score = 32.4 bits (72), Expect = 0.34,   Method: Composition-based stats.
 Identities = 16/60 (26%), Positives = 27/60 (45%), Gaps = 5/60 (8%)

Query: 282 IVVNEVSPDGPAANAG-IQVNDLIISVDNKPA--ISALETMDQVAEIRPGSVIPVVVMRD 338
           +V+  V P GPA   G I+  D ++SVD       +  E M  + +   G    +++  D
Sbjct: 34  VVITSVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQC--GQEAALLIEYD 91


>1WFV-A nrPDB
          Length = 103

 Score = 32.4 bits (72), Expect = 0.34,   Method: Composition-based stats.
 Identities = 14/66 (21%), Positives = 27/66 (40%), Gaps = 1/66 (1%)

Query: 274 GGIDQLQGIVVNEVSPDGPAANAG-IQVNDLIISVDNKPAISALETMDQVAEIRPGSVIP 332
           GG +    + V  ++ DGPA   G ++V D II ++ +                 G  + 
Sbjct: 30  GGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIKSGGRRVR 89

Query: 333 VVVMRD 338
           +++ R 
Sbjct: 90  LLLKRG 95


>6FAH-A nrPDB
          Length = 396

 Score = 31.6 bits (70), Expect = 0.47,   Method: Composition-based stats.
 Identities = 30/157 (19%), Positives = 58/157 (36%), Gaps = 14/157 (8%)

Query: 167 TITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGA---LVNSLGELMGINTLSFDKS 223
           T+  G+     +   +P+ +   ++ DA+ N G+       +V +  + + I+   F  S
Sbjct: 225 TVRPGV---MDKAAYDPSQKGEVIKLDATFNEGDIRTKVLEIVKTTTDNISISDADFIVS 281

Query: 224 NDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREIAPLHAQGGGIDQLQGIV 283
                 +  GF    +L  ++ DKL       R  +  G  + A       G      I 
Sbjct: 282 GGMGLGKPEGF----ELLKQLADKLGGTVATSRACVDAGWADHA-QQVGQTGTTVKPQIY 336

Query: 284 VNEVSPDGPAANAGIQVNDLIISVD---NKPAISALE 317
                       AG+Q +D+II+++   N P     +
Sbjct: 337 FACGISGAIQHIAGMQDSDIIIAINKNENAPIFEVAD 373


>4NXP-A nrPDB
          Length = 94

 Score = 31.6 bits (70), Expect = 0.50,   Method: Composition-based stats.
 Identities = 11/41 (26%), Positives = 21/41 (51%)

Query: 272 QGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPA 312
                D ++ + VN V   G A+  G++  D I+ ++N+ A
Sbjct: 27  SSVEEDGIRRLYVNSVKETGLASKKGLKAGDEILEINNRAA 67


>1U3B-A nrPDB
          Length = 185

 Score = 31.2 bits (69), Expect = 0.68,   Method: Composition-based stats.
 Identities = 12/79 (15%), Positives = 33/79 (41%), Gaps = 3/79 (3%)

Query: 262 GGREIAPLHAQGGGIDQLQGIVVNEVSPDGPAANAG-IQVNDLIISVDNKPAIS--ALET 318
            G  +  +  + G    L  +++  +   GPA  +G + + D I+S++    +       
Sbjct: 11  KGEILGVVIVESGWGSILPTVIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTC 70

Query: 319 MDQVAEIRPGSVIPVVVMR 337
              +  ++  S + + ++R
Sbjct: 71  QSIIKGLKNQSRVKLNIVR 89



 Score = 28.9 bits (63), Expect = 3.2,   Method: Composition-based stats.
 Identities = 10/46 (21%), Positives = 18/46 (39%), Gaps = 1/46 (2%)

Query: 268 PLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAI 313
           P      G     GI +  +   G A   G++V   II ++ +  +
Sbjct: 101 PDLRYQLGFSVQNGI-ICSLMRGGIAERGGVRVGHRIIEINGQSVV 145


>1X5R-A nrPDB
          Length = 112

 Score = 31.2 bits (69), Expect = 0.74,   Method: Composition-based stats.
 Identities = 13/62 (20%), Positives = 24/62 (38%), Gaps = 3/62 (4%)

Query: 283 VVNEVSPDGPAANAG-IQVNDLIISVDNKPAISAL--ETMDQVAEIRPGSVIPVVVMRDD 339
           +V  + PD PA   G +QV D ++S++          E    + +      + + V  D 
Sbjct: 48  LVCFIEPDSPAERCGLLQVGDRVLSINGIATEDGTMEEANQLLRDAALAHKVVLEVEFDS 107

Query: 340 KQ 341
             
Sbjct: 108 GP 109


>2I6V-A nrPDB
          Length = 87

 Score = 31.2 bits (69), Expect = 0.79,   Method: Composition-based stats.
 Identities = 10/64 (15%), Positives = 24/64 (37%), Gaps = 3/64 (4%)

Query: 286 EVSPDGPA---ANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDDKQL 342
            VSP        + G+Q  D+ ++++                +   + + + V RD +Q 
Sbjct: 22  RVSPGKDPVLFESIGLQDGDMAVALNGLDLTDPNVMNTLFQSMNEMTEMSLTVERDGQQH 81

Query: 343 TLQV 346
            + +
Sbjct: 82  DVYI 85


>2WV5-A nrPDB
          Length = 214

 Score = 30.8 bits (68), Expect = 0.84,   Method: Composition-based stats.
 Identities = 25/126 (19%), Positives = 45/126 (35%), Gaps = 10/126 (7%)

Query: 113 VFEALLVGSDSLTDLAVLKINATGGLPTIP--INARRVPHIGDVVLAIGNPYNLGQTITQ 170
            FE  + G D L+D A++ ++    +  I            G  V+ + N  ++G+ I  
Sbjct: 72  EFEIKVKGQDMLSDAALMVLHRGNKVRDITKHFRDTARMKKGTPVVGVVNNADVGRLIFS 131

Query: 171 GIISATGRIGLNPTGRQ--NFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGET 228
           G       I +   G          A+   G +GGA++   G        +F        
Sbjct: 132 GEALTYKDIVVLMDGDTMPGLFAYKAATRAGYAGGAVLAKDG------ADTFIVGTHSAG 185

Query: 229 PEGIGF 234
             G+G+
Sbjct: 186 GNGVGY 191


>1CT4-E nrPDB
          Length = 185

 Score = 30.8 bits (68), Expect = 0.88,   Method: Composition-based stats.
 Identities = 25/135 (18%), Positives = 42/135 (31%), Gaps = 11/135 (8%)

Query: 78  TLGSGVIMDQRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLK-----I 132
           +LG  V      Y +T  H  + A           V       S    D  +++     I
Sbjct: 15  SLGFNVRSGSTYYFLTAGHCTDGATTWWANSARTTVLGTTSGSSFPNNDYGIVRYTNTTI 74

Query: 133 NATGGLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNF--L 190
              G +    I +     +G  V   G+          G ++A         G   +  +
Sbjct: 75  PKDGTVGGQDITSAANATVGMAVTRRGSTTGTH----SGSVTALNATVNYGGGDVVYGMI 130

Query: 191 QTDASINHGNSGGAL 205
           +T+     G+SGG L
Sbjct: 131 RTNVCAEPGDSGGPL 145


>2I4S-A nrPDB
          Length = 105

 Score = 30.8 bits (68), Expect = 0.97,   Method: Composition-based stats.
 Identities = 10/64 (15%), Positives = 24/64 (37%), Gaps = 3/64 (4%)

Query: 286 EVSPDGPA---ANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDDKQL 342
            VSP        + G+Q  D+ ++++                +   + + + V RD +Q 
Sbjct: 40  RVSPGKDPVLFESIGLQDGDMAVALNGLDLTDPNVMNTLFQSMNEMTEMSLTVERDGQQH 99

Query: 343 TLQV 346
            + +
Sbjct: 100 DVYI 103


>2SGA-A nrPDB
          Length = 181

 Score = 30.8 bits (68), Expect = 1.0,   Method: Composition-based stats.
 Identities = 24/135 (17%), Positives = 45/135 (33%), Gaps = 13/135 (9%)

Query: 78  TLGSGVIMDQRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGG 137
           +LG  V ++   + +T  H  N +    +  + G  F     G    ++ A     A  G
Sbjct: 15  SLGFNVSVNGVAHALTAGHCTNISASWSIGTRTGTSFPNNDYGIIRHSNPA-----AADG 69

Query: 138 LPTIPINARRVPH------IGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQ 191
              +   + +         +G  V   G+   L      G+ +               +Q
Sbjct: 70  RVYLYNGSYQDITTAGNAFVGQAVQRSGSTTGLRSGSVTGLNATVNYGSSGI--VYGMIQ 127

Query: 192 TDASINHGNSGGALV 206
           T+     G+SGG+L 
Sbjct: 128 TNVCAQPGDSGGSLF 142


>1PQ7-A nrPDB
          Length = 224

 Score = 30.4 bits (67), Expect = 1.1,   Method: Composition-based stats.
 Identities = 35/160 (21%), Positives = 60/160 (37%), Gaps = 38/160 (23%)

Query: 91  IITNKHVINDADQIIVALQDG---RVFEALLVG----------SDSLTDLAVLKINAT-- 135
           ++T  H ++   Q    ++ G   R    +             S +  DLA+LK++ +  
Sbjct: 36  VLTAAHCVSGYAQSGFQIRAGSLSRTSGGITSSLSSVRVHPSYSGNNNDLAILKLSTSIP 95

Query: 136 --GGLPTIPINAR-RVPHIGDVVLAIG----------NPYNLGQTITQGIIS-ATGRIGL 181
             G +    + A    P  G      G           P NL + +T  I+S AT R   
Sbjct: 96  SGGNIGYARLAASGSDPVAGSSATVAGWGATSEGGSSTPVNLLK-VTVPIVSRATCRAQY 154

Query: 182 NPTGRQNFLQTDASINHG-------NSGGALVNSLGELMG 214
             +   N +   A ++ G       +SGG +V+S   L+G
Sbjct: 155 GTSAITNQMFC-AGVSSGGKDSCQGDSGGPIVDSSNTLIG 193


>3SUZ-A nrPDB
          Length = 388

 Score = 30.4 bits (67), Expect = 1.1,   Method: Composition-based stats.
 Identities = 10/49 (20%), Positives = 19/49 (38%), Gaps = 1/49 (2%)

Query: 268 PLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISAL 316
           P      G     GI +  +   G A   G++V   II ++ +  ++  
Sbjct: 304 PDLKYQLGFSVQNGI-ICSLMRGGIAERGGVRVGHRIIEINGQSVVATA 351


>1U37-A nrPDB
          Length = 89

 Score = 30.4 bits (67), Expect = 1.2,   Method: Composition-based stats.
 Identities = 12/79 (15%), Positives = 33/79 (41%), Gaps = 3/79 (3%)

Query: 262 GGREIAPLHAQGGGIDQLQGIVVNEVSPDGPAANAG-IQVNDLIISVDNKPAIS--ALET 318
            G  +  +  + G    L  +++  +   GPA  +G + + D I+S++    +       
Sbjct: 11  KGEILGVVIVESGWGSILPTVIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTC 70

Query: 319 MDQVAEIRPGSVIPVVVMR 337
              +  ++  S + + ++R
Sbjct: 71  QSIIKGLKNQSRVKLNIVR 89


>1ZZM-A nrPDB
          Length = 259

 Score = 30.1 bits (66), Expect = 1.5,   Method: Composition-based stats.
 Identities = 11/56 (19%), Positives = 18/56 (32%)

Query: 139 PTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDA 194
             +           +  + +G    +G TIT    S T  +          L+TDA
Sbjct: 153 TGVVHGFSGSLQQAERFVQLGYKIGVGGTITYPRASKTRDVIAKLPLASLLLETDA 208


>4OEP-A nrPDB
          Length = 107

 Score = 30.1 bits (66), Expect = 1.8,   Method: Composition-based stats.
 Identities = 12/56 (21%), Positives = 22/56 (39%), Gaps = 1/56 (1%)

Query: 282 IVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMR 337
           IV+++V   GPA    +Q ND +  V+     +           + G    + + R
Sbjct: 41  IVISDVLKGGPAE-GQLQENDRVAMVNGVSMDNVEHAFAVQQLRKSGKNAKITIRR 95


>2SFA-A nrPDB
          Length = 191

 Score = 29.7 bits (65), Expect = 1.8,   Method: Composition-based stats.
 Identities = 14/58 (24%), Positives = 21/58 (36%), Gaps = 6/58 (10%)

Query: 151 IGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTG--RQNFLQTDASINHGNSGGALV 206
           +G  V   G+   L      G ++          G      +QT+     G+SGGAL 
Sbjct: 99  VGQTVQRSGSTTGLH----SGRVTGLNATVNYGGGDIVSGLIQTNVCAEPGDSGGALF 152


>1Y7N-A nrPDB
          Length = 90

 Score = 29.7 bits (65), Expect = 1.9,   Method: Composition-based stats.
 Identities = 10/46 (21%), Positives = 18/46 (39%), Gaps = 1/46 (2%)

Query: 268 PLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAI 313
           P      G     GI +  +   G A   G++V   II ++ +  +
Sbjct: 20  PDLRYQLGFSVQNGI-ICSLMRGGIAERGGVRVGHRIIEINGQSVV 64


>5MV8-B nrPDB
          Length = 130

 Score = 29.7 bits (65), Expect = 2.1,   Method: Composition-based stats.
 Identities = 13/56 (23%), Positives = 21/56 (37%), Gaps = 2/56 (3%)

Query: 263 GREIAPLHAQGGGIDQLQGIVVNEV--SPDGPAANAGIQVNDLIISVDNKPAISAL 316
            +E +   A  GG+D   G VV            + GI   D I++++ K      
Sbjct: 37  KKEGSLDLALEGGVDSPIGKVVVSAVYERGAAERHGGIVKGDEIMAINGKIVTDYT 92


>3EGH-C nrPDB
          Length = 170

 Score = 29.7 bits (65), Expect = 2.1,   Method: Composition-based stats.
 Identities = 16/59 (27%), Positives = 26/59 (44%), Gaps = 1/59 (1%)

Query: 281 GIVVNEVSPDGPAANAG-IQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRD 338
           GI V  V+  G A   G IQVNDL++ VD    +   ++            +  ++ R+
Sbjct: 112 GIFVKTVTEGGAAHRDGRIQVNDLLVEVDGTSLVGVTQSFAASVLRNTKGRVRFMIGRE 170


>1UEW-A nrPDB
          Length = 114

 Score = 29.7 bits (65), Expect = 2.3,   Method: Composition-based stats.
 Identities = 13/56 (23%), Positives = 24/56 (42%), Gaps = 1/56 (1%)

Query: 260 GIGGREIAPLHAQGGGIDQLQGIVVNEVSPDGPAAN-AGIQVNDLIISVDNKPAIS 314
           G G   I+ L+    G        +  +    PA   A ++V D I++V+ +  I+
Sbjct: 23  GFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIIN 78


>2WV9-A nrPDB
          Length = 673

 Score = 29.3 bits (64), Expect = 2.5,   Method: Composition-based stats.
 Identities = 12/33 (36%), Positives = 17/33 (51%), Gaps = 2/33 (6%)

Query: 183 PTGRQNFLQTDASINHGNSGGALVNSLGELMGI 215
             G    +  D  I  G SG  +VNS GE++G+
Sbjct: 173 AHGEIGAVSLDYPI--GTSGSPIVNSNGEIIGL 203


>1V6B-A nrPDB
          Length = 118

 Score = 29.3 bits (64), Expect = 2.5,   Method: Composition-based stats.
 Identities = 15/56 (26%), Positives = 25/56 (44%), Gaps = 2/56 (3%)

Query: 263 GREIAPLHAQGGGIDQLQG-IVVNEVSPDGPAAN-AGIQVNDLIISVDNKPAISAL 316
            +E +   A  GG+D   G +VV+ V   G A    G+   D I++++ K      
Sbjct: 25  KKEGSLDLALEGGVDSPVGKVVVSAVYEGGAAERHGGVVKGDEIMAINGKIVTDYT 80


>3GX9-A nrPDB
          Length = 377

 Score = 29.3 bits (64), Expect = 3.0,   Method: Composition-based stats.
 Identities = 14/32 (43%), Positives = 17/32 (53%), Gaps = 3/32 (9%)

Query: 29  LNPLSTPQFDSTDETPA---SYNLAVRRAAPA 57
           L+P STP+   TDE P     Y  A +RA  A
Sbjct: 147 LHPTSTPRALETDEIPGIVEDYRQAAQRAKRA 178


>2WZQ-A nrPDB
          Length = 619

 Score = 28.9 bits (63), Expect = 3.4,   Method: Composition-based stats.
 Identities = 6/18 (33%), Positives = 12/18 (66%)

Query: 198 HGNSGGALVNSLGELMGI 215
            G SG  ++N  G+++G+
Sbjct: 132 PGTSGSPIINKKGKVIGL 149


>1YJS-A nrPDB
          Length = 419

 Score = 28.9 bits (63), Expect = 3.7,   Method: Composition-based stats.
 Identities = 13/49 (26%), Positives = 17/49 (34%), Gaps = 2/49 (4%)

Query: 160 NPYNLGQTITQGIISATG--RIGLNPTGRQNFLQTDASINHGNSGGALV 206
           NP      +T          R G+     Q   Q D +I  G  GG L+
Sbjct: 212 NPVPYAHFVTTTTHQTLRGPRGGMILCQEQFAKQIDKAIFPGIQGGPLM 260


>1U39-A nrPDB
          Length = 80

 Score = 28.5 bits (62), Expect = 4.4,   Method: Composition-based stats.
 Identities = 10/46 (21%), Positives = 18/46 (39%), Gaps = 1/46 (2%)

Query: 268 PLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAI 313
           P      G     GI +  +   G A   G++V   II ++ +  +
Sbjct: 11  PDLRYQLGFSVQNGI-ICSLMRGGIAERGGVRVGHRIIEINGQSVV 55


>1AZZ-A nrPDB
          Length = 226

 Score = 28.5 bits (62), Expect = 4.5,   Method: Composition-based stats.
 Identities = 35/168 (20%), Positives = 57/168 (33%), Gaps = 38/168 (22%)

Query: 82  GVIMDQRGYIITNKHVINDADQIIVAL--QDGRVFEALLVGSDSL--------------T 125
           G ++    +I+T  H ++ A  + V L   + R  EA  V   S                
Sbjct: 28  GSLISPE-WILTAAHCMDGAGFVDVVLGAHNIREDEATQVTIQSTDFTVHENYNSFVISN 86

Query: 126 DLAVLKINATGGLPTIPINA---RRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLN 182
           D+AV+++     L               +G VV   G  + L      GI     ++ + 
Sbjct: 87  DIAVIRLPVPVTLTAAIATVGLPSTDVGVGTVVTPTG--WGLPSDSALGISDVLRQVDVP 144

Query: 183 PTGRQN-----FLQTDASI----------NHGNSGGALVNSLGELMGI 215
                +      + TD +I           +G+SGG L N  G   GI
Sbjct: 145 IMSNADCDAVYGIVTDGNICIDSTGGKGTCNGDSGGPL-NYNGLTYGI 191


>1GBE-A nrPDB
          Length = 198

 Score = 28.5 bits (62), Expect = 5.1,   Method: Composition-based stats.
 Identities = 28/166 (16%), Positives = 50/166 (30%), Gaps = 22/166 (13%)

Query: 92  ITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPT--------IPI 143
           +T  H         +       F A +       D A + + +   L          + +
Sbjct: 32  VTAGHCGTVNATARIGGAVVGTFAARVF---PGNDRAWVSLTSAQTLLPRVANGSSFVTV 88

Query: 144 NARRVPHIGDVVLAIGNPYNLG-QTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSG 202
                  +G  V   G        TIT   ++A           +   Q +A    G+SG
Sbjct: 89  RGSTEAAVGAAVCRSGRTTGYQCGTITAKNVTA----NYAEGAVRGLTQGNACAGRGDSG 144

Query: 203 GALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKL 248
           G+ + S G+  G+       S       G    IP    + + ++L
Sbjct: 145 GSWITSAGQAQGV------MSGLNVQSNGNNCGIPASQRSSLFERL 184


>3NK6-A nrPDB
          Length = 277

 Score = 28.1 bits (61), Expect = 5.4,   Method: Composition-based stats.
 Identities = 19/98 (19%), Positives = 37/98 (37%), Gaps = 8/98 (8%)

Query: 85  MDQRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDS--------LTDLAVLKINATG 136
           +   G ++ +  +   AD+ ++    G VF   +V +D           D+A++ ++  G
Sbjct: 143 LGAAGIVLVDSDLATIADRRLLRASRGYVFSLPVVLADREEAVSFLRDNDIALMVLDTDG 202

Query: 137 GLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIIS 174
            L    +  R            G P  L Q  + G +S
Sbjct: 203 DLGVKDLGDRADRMALVFGSEKGGPSGLFQEASAGTVS 240


>1V62-A nrPDB
          Length = 117

 Score = 28.1 bits (61), Expect = 5.9,   Method: Composition-based stats.
 Identities = 7/56 (12%), Positives = 18/56 (32%), Gaps = 1/56 (1%)

Query: 282 IVVNEVSPDGPAANAG-IQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVM 336
           I ++ + P      +G +   D I+S+D                      + + ++
Sbjct: 44  ITIDRIKPASVVDRSGALHPGDHILSIDGTSMEHCSLLEATKLLASISEKVRLEIL 99


>6N4D-A nrPDB
          Length = 397

 Score = 27.7 bits (60), Expect = 6.9,   Method: Composition-based stats.
 Identities = 22/85 (25%), Positives = 35/85 (41%), Gaps = 1/85 (1%)

Query: 197 NHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIR 256
           N G  G A  N     MG  T+S D  +  ET + IG        +++  ++I D     
Sbjct: 274 NPGVKGWAFDNDNDVWMG-RTISKDLRSGYETFKVIGGWTTANSKSQVNRQVIVDNNNWS 332

Query: 257 GYIGIGGREIAPLHAQGGGIDQLQG 281
           GY GI   E      +   ++ ++G
Sbjct: 333 GYSGIFSVEGKSCVNRCFYVELIRG 357


>3BSF-A nrPDB
          Length = 254

 Score = 27.7 bits (60), Expect = 7.5,   Method: Composition-based stats.
 Identities = 13/46 (28%), Positives = 18/46 (39%), Gaps = 3/46 (6%)

Query: 169 TQGIIS-ATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELM 213
           T G+ S  T    L        +Q D  IN G +GG    + G  +
Sbjct: 71  TLGVESVGTVPASLVTYASILAIQPDLIINAGTAGG--FKAKGACI 114


>1P3E-A nrPDB
          Length = 215

 Score = 27.7 bits (60), Expect = 8.6,   Method: Composition-based stats.
 Identities = 26/164 (15%), Positives = 51/164 (31%), Gaps = 27/164 (16%)

Query: 90  YIITNKHVINDADQIIVALQDGRVFEAL---------------------LVGSDSLTDLA 128
            I+TN H + +      + + G V+  +                     +    S  D A
Sbjct: 41  KILTNGHCVYNTASRSYSAK-GSVYPGMNDSTAVNGSANMTEFYVPSGYINTGASQYDFA 99

Query: 129 VLKINAT--GGLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGR 186
           V+K +      +    I        G  +   G P    +  + G +S     G      
Sbjct: 100 VIKTDTNIGNTVGYRSIRQVTNL-TGTTIKISGYP--GDKMRSTGKVSQWEMSGSVTRED 156

Query: 187 QNFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPE 230
            N          GNSG A+++   +++G++   +        P+
Sbjct: 157 TNLAYYTIDTFSGNSGSAMLDQNQQIVGVHNAGYSNGTINGGPK 200


  Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
    Posted date:  Jan 3, 2023  9:05 PM
  Number of letters in database: 10,336,785
  Number of sequences in database:  36,641
  
Lambda     K      H
   0.310    0.132    0.335 

Lambda     K      H
   0.267   0.0407    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,228,449
Number of Sequences: 36641
Number of extensions: 479292
Number of successful extensions: 1936
Number of sequences better than 10.0: 147
Number of HSP's better than 10.0 without gapping: 134
Number of HSP's successfully gapped in prelim test: 87
Number of HSP's that attempted gapping in prelim test: 1554
Number of HSP's gapped (non-prelim): 249
length of query: 355
length of database: 10,336,785
effective HSP length: 98
effective length of query: 257
effective length of database: 6,745,967
effective search space: 1733713519
effective search space used: 1733713519
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.2 bits)
S2: 60 (27.7 bits)