BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P0AEB2 (403 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1NZO-A nrPDB 740 0.0 3ITA-A nrPDB 474 e-134 5TR7-A nrPDB 418 e-117 3A3J-A nrPDB 376 e-105 5FSR-A nrPDB 365 e-101 4K91-A nrPDB 330 5e-91 6OSU-A nrPDB 196 2e-50 3MFD-A nrPDB 111 5e-25 1SKF-A nrPDB 102 2e-22 1XP4-A nrPDB 97 9e-21 3HUM-A nrPDB 95 5e-20 1TVF-A nrPDB 95 6e-20 5ZQC-A nrPDB 85 5e-17 4RYE-A nrPDB 84 1e-16 4PPR-A nrPDB 71 9e-13 6AZI-A nrPDB 69 5e-12 6MUQ-A nrPDB 59 3e-09 6GY8-A nrPDB 32 0.38 5OF3-B nrPDB 32 0.45 5OFN-B nrPDB 32 0.47 1ZT2-B nrPDB 32 0.48 5ODC-F nrPDB 28 5.5 3QN3-A nrPDB 28 8.6 >1NZO-A nrPDB Length = 363 Score = 740 bits (1911), Expect = 0.0, Method: Compositional matrix adjust. Identities = 359/363 (98%), Positives = 360/363 (99%) Query: 30 DDLNIKTMIPGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKA 89 DDLNIKTMIPGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKA Sbjct: 1 DDLNIKTMIPGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKA 60 Query: 90 GKFKETDLVTIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMAD 149 GKFKETDLVTIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMAD Sbjct: 61 GKFKETDLVTIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMAD 120 Query: 150 FAAGSQDAFVGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEY 209 FAAGSQDAFVGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEY Sbjct: 121 FAAGSQDAFVGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEY 180 Query: 210 SIYKEKEFTFNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVM 269 SIYKEKEFTFNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVM Sbjct: 181 SIYKEKEFTFNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVM 240 Query: 270 GGRTFKGREAESKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTI 329 GGRTFKGREAESKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTI Sbjct: 241 GGRTFKGREAESKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTI 300 Query: 330 PRGRMKDLKASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEGNFFGK 389 PRGRMKDLKASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEGNF Sbjct: 301 PRGRMKDLKASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEGNFGDP 360 Query: 390 IID 392 +ID Sbjct: 361 VID 363 >3ITA-A nrPDB Length = 352 Score = 474 bits (1220), Expect = e-134, Method: Compositional matrix adjust. Identities = 224/343 (65%), Positives = 278/343 (81%) Query: 42 PQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIG 101 P +DA ++IL+DY SGKVLAE NAD + DPASLTK+MTSYV+GQA+KA K K TD+VT+G Sbjct: 9 PSVDARAWILMDYASGKVLAEGNADEKLDPASLTKIMTSYVVGQALKADKIKLTDMVTVG 68 Query: 102 NDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGL 161 DAWATGNP +GSS+MFLKPG QV V+ L +G+ +QSGNDAC+A+AD+ AGSQ++F+GL Sbjct: 69 KDAWATGNPALRGSSVMFLKPGDQVSVADLNKGVIIQSGNDACIALADYVAGSQESFIGL 128 Query: 162 MNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFTFNG 221 MN Y LGL NT FQTVHGLDA GQ+S+ARDMAL+G+ALI DVP EY+I+KEKEFTFN Sbjct: 129 MNGYAKKLGLTNTTFQTVHGLDAPGQFSTARDMALLGKALIHDVPEEYAIHKEKEFTFNK 188 Query: 222 IRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKGREAES 281 IRQ NRN LLW ++LNVDG+KTG T AGYNLVASAT+G MRLIS V+G +T + R ES Sbjct: 189 IRQPNRNRLLWSSNLNVDGMKTGTTAGAGYNLVASATQGDMRLISVVLGAKTDRIRFNES 248 Query: 282 KKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTIPRGRMKDLKASY 341 +KLLTWGFRFFETV P+K F ++ VWFGD +LG + +TIPRG++K+LKASY Sbjct: 249 EKLLTWGFRFFETVTPIKPDATFVTQRVWFGDKSEVNLGAGEAGSVTIPRGQLKNLKASY 308 Query: 342 VLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEG 384 L +L APL+K QVVGTI+FQL+GK+IEQRPL+V++ + EG Sbjct: 309 TLTEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLIVMENVEEG 351 >5TR7-A nrPDB Length = 341 Score = 418 bits (1075), Expect = e-117, Method: Compositional matrix adjust. Identities = 204/345 (59%), Positives = 255/345 (73%), Gaps = 4/345 (1%) Query: 39 PGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLV 98 P PQI A+ Y+L+DY+SGKVLAE+ D + PASLTKMMTSYVIGQ +K G D V Sbjct: 1 PDAPQIAAKGYVLMDYHSGKVLAEKEMDTKLSPASLTKMMTSYVIGQEVKRGNISLNDDV 60 Query: 99 TIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAF 158 I +AWA F SS MF++ G V VS L RGI +QSGNDACVAMA+ AG++DAF Sbjct: 61 VISKNAWAKN---FPDSSKMFVEVGTTVKVSDLNRGIIIQSGNDACVAMAEHVAGTEDAF 117 Query: 159 VGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFT 218 V LMN++ ++LG+KN+HF HGLD YS+ D+AL+GQALIRDVP EY+IY E++FT Sbjct: 118 VDLMNAWASSLGMKNSHFTNSHGLDDPNLYSTPYDLALLGQALIRDVPEEYAIYSEQKFT 177 Query: 219 FNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKGRE 278 +NGI Q NRNGLLWD S+NVDGIKTGHT AGYNLV+SATEG MRL++ VMG R+ Sbjct: 178 YNGITQYNRNGLLWDKSMNVDGIKTGHTSGAGYNLVSSATEGNMRLVAVVMGTDNENARK 237 Query: 279 AESKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTIPRGRMKDLK 338 AESKKLL++GFRFFETV P K G+ F +E +W GD D +LGVDKD Y+T+PRG+ KDL Sbjct: 238 AESKKLLSYGFRFFETVAPHKAGETFVNETIWMGDKDTIALGVDKDTYVTLPRGQAKDLT 297 Query: 339 ASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPE 383 AS+VL +L APL+K +VGT+ +QL G I Q PL+ L+++ E Sbjct: 298 ASFVL-EKQLKAPLKKGDIVGTLYYQLAGNDIAQYPLLALEDVQE 341 >3A3J-A nrPDB Length = 344 Score = 376 bits (966), Expect = e-105, Method: Compositional matrix adjust. Identities = 191/343 (55%), Positives = 236/343 (68%), Gaps = 4/343 (1%) Query: 42 PQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIG 101 PQI A++Y+L+DYNSG +L N D R+ PASLTKMMTSYV+G A+K GK TD+VTIG Sbjct: 5 PQITAQTYVLMDYNSGAILTALNPDQRQYPASLTKMMTSYVVGVALKQGKIHNTDMVTIG 64 Query: 102 NDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGL 161 AW F SS MFL QV V+ L RG+ + SGNDA VA+A+ +G+ FV Sbjct: 65 ESAWGRN---FPDSSKMFLDLNTQVSVADLNRGVIVVSGNDATVALAEHISGNVPNFVET 121 Query: 162 MNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFTFNG 221 MN YV GLKNT+F T HGLD QYSSARDMA+IG +IRD+P EY IY EK+FTFN Sbjct: 122 MNKYVQQFGLKNTNFTTPHGLDDPNQYSSARDMAIIGAHIIRDLPEEYKIYSEKDFTFNK 181 Query: 222 IRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASA-TEGQMRLISAVMGGRTFKGREAE 280 I+Q NRNGLLWD ++NVDG+KTGHT +AGYNLVASA T MRLIS VMG T+KGRE E Sbjct: 182 IKQPNRNGLLWDKTINVDGMKTGHTSQAGYNLVASATTSNNMRLISVVMGVPTYKGREVE 241 Query: 281 SKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTIPRGRMKDLKAS 340 SKKLL WGF FET L+ GKE + + V++GD + LG D ++TIP+G+ ++KA Sbjct: 242 SKKLLQWGFANFETFKTLEAGKEISEQRVYYGDKNSVKLGAFMDHFITIPKGKQSEVKAR 301 Query: 341 YVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPE 383 Y L L APL K QV+G + + LDGK I L V+ ++ E Sbjct: 302 YELADKNLQAPLAKGQVIGKVVYALDGKDIASANLQVMNDVGE 344 >5FSR-A nrPDB Length = 375 Score = 365 bits (938), Expect = e-101, Method: Compositional matrix adjust. Identities = 173/346 (50%), Positives = 238/346 (68%) Query: 39 PGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLV 98 P P+I A S++L+DY +G++L N +R+PASLTK+MT YV+ +A+ + + D+V Sbjct: 30 PQPPEIHAGSWVLMDYTTGQILTAGNEHQQRNPASLTKLMTGYVVDRAIDSHRITPDDIV 89 Query: 99 TIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAF 158 T+G DAWA NPVF GSSLMFLK G +V V L RG+ + SGNDACVA+AD+ AG Q F Sbjct: 90 TVGRDAWAKDNPVFVGSSLMFLKEGDRVSVRDLSRGLIVDSGNDACVALADYIAGGQRQF 149 Query: 159 VGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFT 218 V +MN+Y L LK+THF+TVHGLDA GQ+SSA D+A++ +A+I P Y +Y EK T Sbjct: 150 VEMMNNYAEKLHLKDTHFETVHGLDAPGQHSSAYDLAVLSRAIIHGEPEFYHMYSEKSLT 209 Query: 219 FNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKGRE 278 +NGI Q NRNGLLWD ++NVDG+KTGHT AG+NL+ASA +GQ RLI+ VMG + KGRE Sbjct: 210 WNGITQQNRNGLLWDKTMNVDGLKTGHTSGAGFNLIASAVDGQRRLIAVVMGADSAKGRE 269 Query: 279 AESKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTIPRGRMKDLK 338 E++KLL WG + F TV L GK+ +E +W+GD + LG +++ ++ +P+ + +K Sbjct: 270 EEARKLLRWGQQNFTTVQILHRGKKVGTERIWYGDKENIDLGTEQEFWMVLPKAEIPHIK 329 Query: 339 ASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEG 384 A Y L+ EL AP+ +Q VG I K + PLV L+ + EG Sbjct: 330 AKYTLDGKELTAPISAHQRVGEIELYDRDKQVAHWPLVTLESVGEG 375 >4K91-A nrPDB Length = 346 Score = 330 bits (847), Expect = 5e-91, Method: Compositional matrix adjust. Identities = 170/352 (48%), Positives = 230/352 (65%), Gaps = 8/352 (2%) Query: 35 KTMIPGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKE 94 ++M+P PQ+ A+SY+L+D SG+VL E N D R PASLTK+MT+Y+ + ++AG+ E Sbjct: 3 ESMVPAPPQLAAKSYVLMDGESGQVLVENNGDQRLPPASLTKLMTAYIATKEIEAGRIGE 62 Query: 95 TDLVTIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGS 154 DLVT+ AW TG S MF+K G QV VS L+ GI +QSGNDA VA+A+ AGS Sbjct: 63 NDLVTVSEHAWRTGG------SRMFIKVGSQVSVSDLLHGIIIQSGNDASVALAEHIAGS 116 Query: 155 QDAFVGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKE 214 +DAF +MN+ LGL N+HF GL YSSARDMA++ +A+I P+ Y+IY + Sbjct: 117 EDAFADMMNTTAQKLGLTNSHFMDATGLPNPDHYSSARDMAVLARAIIYGEPSHYAIYAQ 176 Query: 215 KEFTFNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTF 274 KEF +N I+Q NRN LLW + VDG+KTGHTD+AGY LVASA R+I+ V G + Sbjct: 177 KEFLWNNIKQPNRNLLLWRDK-TVDGLKTGHTDEAGYCLVASAVRDGQRMIAVVFGTNSE 235 Query: 275 KGREAESKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTIPRGRM 334 + R AE++KLLT+GFRFFE+ N K G E VW G G+ +D+ +T+PRG+M Sbjct: 236 QARAAETQKLLTYGFRFFESRNFYKKGTELTKGLVWKGSEHEVKAGLAEDLTMTLPRGQM 295 Query: 335 KDLKASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEGNF 386 + L+AS VL +L AP+Q+ QV+G + +LD K I LV L + EG F Sbjct: 296 QKLQASMVLE-PQLMAPIQQGQVIGKVEVKLDDKVIRSADLVALNAVEEGGF 346 >6OSU-A nrPDB Length = 427 Score = 196 bits (498), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 127/412 (30%), Positives = 204/412 (49%), Gaps = 77/412 (18%) Query: 39 PGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLV 98 P ++DA +++ +DY +G +++E+N DVRR PASLTK+MTSY++ +KAG ++ Sbjct: 30 PANIELDAPAWVTMDYRTGDIVSEKNMDVRRAPASLTKIMTSYIVASEIKAGNLSWDTMI 89 Query: 99 TIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAF 158 I +A +TG S M++K G +V V L+ G+++ SGNDA +A+A++ G+ AF Sbjct: 90 PISENAASTG------GSKMYVKAGAKVSVRNLVTGMDVVSGNDATIALAEYIGGTTQAF 143 Query: 159 VGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFT 218 LMN A+G+ NTHF GL QY++A DMAL+ ++ I + P Y +Y +K Sbjct: 144 TDLMNQTAKAIGMNNTHFANPDGLPGGEQYTTAHDMALLARSYIYNFPEAYKVYDDKGLV 203 Query: 219 FNGIR----------------------------------------------------QLN 226 +N + Q N Sbjct: 204 WNATKQDSVSIADRKQCLPKFDRATGNVIESYTVKDLDDQAKDKCNKLFPKGDNFVLQNN 263 Query: 227 RNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKGREAESKKLLT 286 RN LL+ DG+KTGHTD AGY LV+SA + R IS V+G + R++ES KLL Sbjct: 264 RNRLLFTFD-GADGMKTGHTDAAGYCLVSSAKQDGERFISVVLGTTSSAKRDSESAKLLR 322 Query: 287 WGFRFFETVNPLKVGKEFASEPVWFGDSD--------RASLGVDKDVYLTIPRGRMKDLK 338 + +E V K A+ PV + + ++ ++++Y T+P+ + LK Sbjct: 323 YALSKYENVLLYK-----ANSPVTISADNIPNAKAGQKLTVASNQNIYKTVPKTYVPYLK 377 Query: 339 ASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQ---RPLVVLQEIPEGNFF 387 N + L+AP++ Q VG + L G T E+ P+V + + + ++ Sbjct: 378 QGIEFNPN-LNAPIKTGQTVGNLVITL-GDTKEEIASIPVVAMNNVSQKGWW 427 >3MFD-A nrPDB Length = 334 Score = 111 bits (278), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 80/229 (34%), Positives = 129/229 (56%), Gaps = 15/229 (6%) Query: 44 IDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGND 103 + A+S I+ID SG+VL ++ +R AS+TK+MT+ + A+++GK +T VT+ Sbjct: 7 VSAKSAIIIDGASGRVLYAKDEHQKRRIASITKIMTAVL---AIESGKMDQT--VTV--- 58 Query: 104 AWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGLMN 163 + N V S ++L G +V + L+ G+ L+SGNDA VA+A+ GS D FV +MN Sbjct: 59 ---SANAVRTEGSAIYLTEGQKVKLKDLVYGLMLRSGNDAAVAIAEHVGGSLDGFVYMMN 115 Query: 164 SYVNALGLKNTHFQTVHGL-DADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFTFNGI 222 LG+KNT FQ HGL D + YS+A DMA++ + ++ + + I K + + Sbjct: 116 QKAEQLGMKNTRFQNPHGLDDHENHYSTAYDMAILTKYAMK-LKDYQKISGTKIYKAETM 174 Query: 223 RQL--NRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVM 269 + N+N LL G KTG+T A LV++A++ + LI+ + Sbjct: 175 ESVWKNKNKLLTMLYPYSTGGKTGYTKLAKRTLVSTASKDGIDLIAVTI 223 >1SKF-A nrPDB Length = 262 Score = 102 bits (255), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 86/263 (32%), Positives = 128/263 (48%), Gaps = 21/263 (7%) Query: 42 PQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIG 101 P I A ++ +G L + AD RR S TK+MT+ V+ + VTI Sbjct: 4 PTIAAVGGYAMNNGTGTTLYTKAADTRRSTGSTTKIMTAKVV---LAQSNLNLDAKVTI- 59 Query: 102 NDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMAD-FAAGSQDA--- 157 A++ V +S L G +V V QL+ G+ L SG DA A+AD + +GS A Sbjct: 60 QKAYS-DYVVANNASQAHLIVGDKVTVRQLLYGLMLPSGCDAAYALADKYGSGSTRAARV 118 Query: 158 --FVGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSI---- 211 F+G MN+ LGL NTHF + G+ YS+ RD+ I + +++ + Sbjct: 119 KSFIGKMNTAATNLGLHNTHFDSFDGIGNGANYSTPRDLTKIASSAMKNSTFRTVVKTKA 178 Query: 212 YKEKEFTFNG-IRQL----NRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLIS 266 Y K T G IR + N NGLL S + G+KTG +A Y LV +AT G +I Sbjct: 179 YTAKTVTKTGSIRTMDTWKNTNGLLSSYSGAI-GVKTGSGPEAKYCLVFAATRGGKTVIG 237 Query: 267 AVMGGRTFKGREAESKKLLTWGF 289 V+ + RE+++ K++ +GF Sbjct: 238 TVLASTSIPARESDATKIMNYGF 260 >1XP4-A nrPDB Length = 379 Score = 97.4 bits (241), Expect = 9e-21, Method: Compositional matrix adjust. Identities = 89/345 (25%), Positives = 156/345 (45%), Gaps = 28/345 (8%) Query: 44 IDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGND 103 I A+ I ++ N+GK+L E++A + AS+TK++T Y++ +A++ G + V I + Sbjct: 12 IAAKHAIAVEANTGKILYEKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDY 71 Query: 104 AWA-TGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGLM 162 + T N + S++ V +L+ + S N A +A+A+ AGS+ FV +M Sbjct: 72 PYQLTTNS--EASNIPM--EARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMM 127 Query: 163 NSYVNALGLKNTHFQTVHGLD----ADGQYS----------SARDMALIGQALIRDVPNE 208 + + G+++ GL+ D Y SA D+A++ + LI+ P Sbjct: 128 RAKLLEWGIQDATVVNTTGLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQV 187 Query: 209 YSIYKEKEFTFNGIRQLNRNGLLWDNSL---NVDGIKTGHTDKAGYNLVASATEGQMRLI 265 I K+ TF G+ + N +L DG+KTG TDKAG + V + E MR+I Sbjct: 188 LEITKKPSSTFAGMTITSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVI 247 Query: 266 SAVMGG----RTFKGREAESKKLLTWGFRFFETVNPLKVGKEF--ASEPVWFGDSDRASL 319 + V+ R + L+ + F ++ G + + PV G D Sbjct: 248 TVVLNADHQDNNPYARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVIA 307 Query: 320 GVDKDVYLTIPRGRMKDLKASYVLNSSELHAPLQKNQVVGTINFQ 364 +D+YL G + +S + APL+ VVG + ++ Sbjct: 308 VAPEDIYLIERVGNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYE 352 >3HUM-A nrPDB Length = 453 Score = 95.1 bits (235), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 81/320 (25%), Positives = 144/320 (45%), Gaps = 39/320 (12%) Query: 56 SGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWATGN-PVFKG 114 +G++L + N D + +PAS+TK+MT Y+ +A+ G+ D VT+ N + P Sbjct: 80 TGQLLYQYNIDTKWNPASMTKLMTMYLTLEAVNKGQLSLDDTVTMTNKEYIMSTLPELSN 139 Query: 115 SSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGLMNSYVNALGLKNT 174 + L PG ++ L++ S N A + +A + + FV LMN+ A+G+KNT Sbjct: 140 TKLY---PGQVWTIADLLQITVSNSSNAAALILAKKVSKNTSDFVDLMNNKAKAIGMKNT 196 Query: 175 HFQTVHGL--------------DADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFTFN 220 HF G D + ++ARD A++ +I++ P K+ T + Sbjct: 197 HFVNPTGAENSRLRSFAPTKYKDQERTVTTARDYAILDLHVIKETPKILDFTKQLAPTTH 256 Query: 221 GIRQLNRNGLLWDNSLNV---DGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKGR 277 + N L +++ DG+KTG +D A YN + G+ R+ +MG +K Sbjct: 257 AVTYYTFNFSLEGAKMSLPGTDGLKTGSSDTANYNHTITTKRGKFRINQVIMGAGDYKNL 316 Query: 278 EAESKK------LLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTIPR 331 E ++ L+ F ++ V L G++ + ++ V+ D+Y +P Sbjct: 317 GGEKQRNMMGNALMERSFDQYKYVKILSKGEQRINGKKYY---------VENDLYDVLPS 367 Query: 332 G-RMKDLKASYVLNSSELHA 350 KD K V+ ++HA Sbjct: 368 DFSKKDYKL--VVEDGKVHA 385 >1TVF-A nrPDB Length = 369 Score = 94.7 bits (234), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 81/320 (25%), Positives = 144/320 (45%), Gaps = 39/320 (12%) Query: 56 SGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWATGN-PVFKG 114 +G++L + N D + +PAS+TK+MT Y+ +A+ G+ D VT+ N + P Sbjct: 44 TGQLLYQYNIDTKWNPASMTKLMTMYLTLEAVNKGQLSLDDTVTMTNKEYIMSTLPELSN 103 Query: 115 SSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGLMNSYVNALGLKNT 174 + L PG ++ L++ S N A + +A + + FV LMN+ A+G+KNT Sbjct: 104 TKLY---PGQVWTIADLLQITVSNSSNAAALILAKKVSKNTSDFVDLMNNKAKAIGMKNT 160 Query: 175 HFQTVHGL--------------DADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFTFN 220 HF G D + ++ARD A++ +I++ P K+ T + Sbjct: 161 HFVNPTGAENSRLRSFAPTKYKDQERTVTTARDYAILDLHVIKETPKILDFTKQLAPTTH 220 Query: 221 GIRQLNRNGLLWDNSLNV---DGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKGR 277 + N L +++ DG+KTG +D A YN + G+ R+ +MG +K Sbjct: 221 AVTYYTFNFSLEGAKMSLPGTDGLKTGSSDTANYNHTITTKRGKFRINQVIMGAGDYKNL 280 Query: 278 EAESKK------LLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTIPR 331 E ++ L+ F ++ V L G++ + ++ V+ D+Y +P Sbjct: 281 GGEKQRNMMGNALMERSFDQYKYVKILSKGEQRINGKKYY---------VENDLYDVLPS 331 Query: 332 G-RMKDLKASYVLNSSELHA 350 KD K V+ ++HA Sbjct: 332 DFSKKDYKL--VVEDGKVHA 349 >5ZQC-A nrPDB Length = 276 Score = 85.1 bits (209), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 70/240 (29%), Positives = 115/240 (47%), Gaps = 17/240 (7%) Query: 57 GKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKF---KETDLVTIGNDAWATGNPVFK 113 G+ L EQNAD ASL+K+MT++++ +A+ + ++ DLV + + + Sbjct: 46 GEALYEQNADKVMPIASLSKLMTAFLVLEAVDNNELSWDEKLDLVRLDDPS--------- 96 Query: 114 GSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGLMNSYVNALGLKN 173 SL + V L + S NDA + D G+ F MN+ LG+ + Sbjct: 97 AVSLYAITQKRTWSVRDLYSAMLTMSANDAAETLGDRLDGAD--FPKEMNNQAKKLGMSS 154 Query: 174 -THFQTVHGLDADGQ--YSSARDMALIGQALIRDVPNEYSIYKEKEFTFNGIRQLNRNGL 230 T F + GLD DG+ S+ +D+ L+ LI P + T + +L Sbjct: 155 KTTFVSASGLDVDGKSAVSTTKDLFLLSSKLISTHPEVLETTSKPTVTTDKGAKLESTND 214 Query: 231 LWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKGREAESKKLLTWGFR 290 L + +DG+KTG TD+AGY + +A G R+IS V+ T + R +++KL+ GF+ Sbjct: 215 LLGSIQGLDGLKTGFTDEAGYCFIGTAERGGKRVISIVLDAGTAEKRFKDTEKLMEVGFK 274 >4RYE-A nrPDB Length = 269 Score = 84.0 bits (206), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 82/269 (30%), Positives = 122/269 (45%), Gaps = 22/269 (8%) Query: 31 DLNIKTMIPGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAG 90 D+ +P +P A+++I+ D +SG+VLA ++ +V PAS K++ + V A+ Sbjct: 6 DVQPAGSVP-IPDGPAQTWIVADLDSGQVLAGRDQNVAHPPASTIKVLLALV---ALDEL 61 Query: 91 KFKETDLVTIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADF 150 T + + D A N V +KPG QL+ G+ L SGNDA +A Sbjct: 62 DLNSTVVADVA-DTQAECNCV-------GVKPGRSYTARQLLDGLLLVSGNDAANTLAHM 113 Query: 151 AAGSQDAFVGLMNSYVNALGLKNTHFQTVHGLDADG--QYSSARDMALIGQALIRDVPNE 208 G QD V MN+ LG +TH T GLD G S+A D+ +I +A + + P Sbjct: 114 -LGGQDVTVAKMNAKAATLGATSTHATTPSGLDGPGGSGASTAHDLVVIFRAAMAN-PVF 171 Query: 209 YSIYKEKEFTF---NGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLI 265 I E F NG + + L G KTG+T+ A V +A G RL+ Sbjct: 172 AQITAEPSAMFPSDNGEQLIVNQDELLQRYPGAIGGKTGYTNAARKTFVGAAARGGRRLV 231 Query: 266 SAVMGGRTFKGREA---ESKKLLTWGFRF 291 A+M G +G ++ L WGF Sbjct: 232 IAMMYGLVKEGGPTYWDQAATLFDWGFAL 260 >4PPR-A nrPDB Length = 334 Score = 70.9 bits (172), Expect = 9e-13, Method: Compositional matrix adjust. Identities = 70/258 (27%), Positives = 115/258 (44%), Gaps = 21/258 (8%) Query: 39 PGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLV 98 P + AE++++ D +SG V+A ++ R PAS+ K++ + + + Sbjct: 53 PAPGDVSAEAWLVADLDSGAVIAARDPHGRHRPASVIKVLVA-----------MASINTL 101 Query: 99 TIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAF 158 T+ T + + + + G V+QL+ G+ + SGNDA A+A G A Sbjct: 102 TLNKSVAGTADDAAVEGTKVGVNTGGTYTVNQLLHGLLMHSGNDAAYALA-RQLGGMPAA 160 Query: 159 VGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFT 218 + +N LG ++T T GLD G +SA D+ L + ++ P I + F Sbjct: 161 LEKINLLAAKLGGRDTRVATPSGLDGPGMSTSAYDIGLFYRYAWQN-PVFADIVATRTFD 219 Query: 219 F------NGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVM-GG 271 F G N N LL+ N G KTG+TD AG V +A RL++ ++ G Sbjct: 220 FPGHGDHPGYELENDNQLLY-NYPGALGGKTGYTDDAGQTFVGAANRDGRRLMTVLLHGT 278 Query: 272 RTFKGREAESKKLLTWGF 289 R ++ LL +GF Sbjct: 279 RQPIPPWEQAAHLLDYGF 296 >6AZI-A nrPDB Length = 285 Score = 68.6 bits (166), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 72/259 (27%), Positives = 115/259 (44%), Gaps = 31/259 (11%) Query: 42 PQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIG 101 PQI + S +++D N+ KV+ + D+ R A +TK+MT+ V+ A E V I Sbjct: 15 PQIASGSAMIVDLNTNKVIYASHPDLVRPIAXITKLMTAMVVLDAHL--PLDEKLKVDIS 72 Query: 102 NDAWATGNPVFKGSSLMFLKPGMQVPVSQ---LIRGINLQSGNDACVAMADFAAGSQDAF 158 + P KG ++ + + +S+ L+ + + S N A ++A G DAF Sbjct: 73 H------TPEMKG---VYSRVRLNSEISRKNMLLLAL-MSSENRAAASLAHHYPGGYDAF 122 Query: 159 VGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMA----------LIGQALIRDVPNE 208 + MN+ ALG+ NT F GL S+ARD+ LIGQ + E Sbjct: 123 IRAMNAKAKALGMNNTRFVEPTGLSIHN-VSTARDLTKLLIASKQYPLIGQ--LSTTREE 179 Query: 209 YSIYKEKEFTFNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAV 268 + + +T R N N L++ + N+ KTG T+ AG+ LV + V Sbjct: 180 MATFANPAYTL-PFR--NTNHLVYRENWNIQLTKTGFTNAAGHCLVMRTVFNGKPVALVV 236 Query: 269 MGGRTFKGREAESKKLLTW 287 M A++ +L TW Sbjct: 237 MDAFGKYTHFADASRLRTW 255 >6MUQ-A nrPDB Length = 283 Score = 59.3 bits (142), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 59/255 (23%), Positives = 114/255 (44%), Gaps = 25/255 (9%) Query: 43 QIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGN 102 ++ + S +++D + KV+ NAD AS+TK+MT+ V+ A K +++++ Sbjct: 13 ELASGSAMVVDLQTNKVIYANNADEVVPIASITKLMTAMVVLDA----KLPLDEIISVDI 68 Query: 103 DAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGLM 162 VF ++ ++ ++ + S N A ++A G +AF+ M Sbjct: 69 HQTKEMKGVFSR-----VRVNSEISRKDMLLLALMSSENRAAASLAHHYPGGYNAFINAM 123 Query: 163 NSYVNALGLKNTHFQTVHGLDADGQYSSARDMA----------LIGQALIRDVPNEYSIY 212 N+ +LG+ T + GL + S+ARD+ LIGQ + + + + Sbjct: 124 NAKAKSLGMTKTRYVEPTGLSINN-VSTARDLTKLLIATKQYPLIGQ--LSTTTEKMATF 180 Query: 213 KEKEFTFNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGR 272 +E +T R N N L++++ N+ KTG T++AG+ L G + V+ Sbjct: 181 REPNYTL-PFR--NTNHLVYNDKWNIQLTKTGFTNQAGHCLAMRTVIGNRPVALVVLDAF 237 Query: 273 TFKGREAESKKLLTW 287 A++ +L +W Sbjct: 238 GKYTHFADANRLRSW 252 >6GY8-A nrPDB Length = 408 Score = 32.3 bits (72), Expect = 0.38, Method: Compositional matrix adjust. Identities = 18/48 (37%), Positives = 26/48 (54%) Query: 53 DYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTI 100 D +S + LAE+ V P++ KM+TS G A G F + DL+ I Sbjct: 4 DMSSNQTLAEKKIPVSEVPSATLKMLTSQAEGVARPGGIFTKGDLINI 51 >5OF3-B nrPDB Length = 307 Score = 32.0 bits (71), Expect = 0.45, Method: Compositional matrix adjust. Identities = 23/53 (43%), Positives = 30/53 (56%), Gaps = 5/53 (9%) Query: 335 KDLKASYVLNSSELH---APLQKNQVVGTINFQLDGKTIEQ-RPLVVLQEIPE 383 KDLK + L+ LH L KNQ++G I + K +E RPL L+EIPE Sbjct: 150 KDLKEDWKLSGQILHKGYVYLDKNQLIGLIAESIKSKIVEMIRPL-NLKEIPE 201 >5OFN-B nrPDB Length = 324 Score = 32.0 bits (71), Expect = 0.47, Method: Compositional matrix adjust. Identities = 23/53 (43%), Positives = 30/53 (56%), Gaps = 5/53 (9%) Query: 335 KDLKASYVLNSSELH---APLQKNQVVGTINFQLDGKTIEQ-RPLVVLQEIPE 383 KDLK + L+ LH L KNQ++G I + K +E RPL L+EIPE Sbjct: 150 KDLKEDWKLSGQILHKGYVYLDKNQLIGLIAESIKSKIVEMIRPL-NLKEIPE 201 >1ZT2-B nrPDB Length = 212 Score = 32.0 bits (71), Expect = 0.48, Method: Compositional matrix adjust. Identities = 23/53 (43%), Positives = 30/53 (56%), Gaps = 5/53 (9%) Query: 335 KDLKASYVLNSSELH---APLQKNQVVGTINFQLDGKTIEQ-RPLVVLQEIPE 383 KDLK + L+ LH L KNQ++G I + K +E RPL L+EIPE Sbjct: 150 KDLKEDWKLSGQILHKGYVYLDKNQLIGLIAESIKSKIVEMIRPL-NLKEIPE 201 >5ODC-F nrPDB Length = 473 Score = 28.5 bits (62), Expect = 5.5, Method: Compositional matrix adjust. Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 1/58 (1%) Query: 248 KAGYNLVASATEGQMRLISAVMGGRTFKGREAESKKLLTWGFRFFE-TVNPLKVGKEF 304 KAG N+V + ++AV+GG++ +E E +LL R E + ++VGK+ Sbjct: 148 KAGQNVVRVVGGRAIHPVTAVVGGQSKSLKEEERDELLKLSERTIELSEKSIEVGKKL 205 >3QN3-A nrPDB Length = 417 Score = 27.7 bits (60), Expect = 8.6, Method: Compositional matrix adjust. Identities = 15/66 (22%), Positives = 32/66 (48%), Gaps = 6/66 (9%) Query: 100 IGNDAWATGNPVF------KGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAG 153 +G+D + T + K ++ + +KP ++Q +R + L N+ M+ + Sbjct: 308 VGDDLFVTNEDILREGIIKKMANAVLIKPNQIGTITQTMRTVRLAQRNNYKCVMSHRSGE 367 Query: 154 SQDAFV 159 S+DAF+ Sbjct: 368 SEDAFI 373 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1NZO-A nrPDB 531 e-151 5FSR-A nrPDB 469 e-133 3ITA-A nrPDB 463 e-131 5TR7-A nrPDB 448 e-126 4K91-A nrPDB 443 e-125 3A3J-A nrPDB 432 e-122 6OSU-A nrPDB 340 7e-94 1XP4-A nrPDB 304 4e-83 3HUM-A nrPDB 264 4e-71 1TVF-A nrPDB 261 5e-70 3MFD-A nrPDB 253 1e-67 4PPR-A nrPDB 241 4e-64 6MUQ-A nrPDB 234 6e-62 5ZQC-A nrPDB 232 2e-61 6AZI-A nrPDB 231 3e-61 4RYE-A nrPDB 231 6e-61 1SKF-A nrPDB 211 5e-55 Sequences not found previously or not previously below threshold: 4QY5-A nrPDB 55 6e-08 2V1Z-A nrPDB 52 3e-07 3GMW-A nrPDB 52 5e-07 5AQB-A nrPDB 51 9e-07 5AQ9-A nrPDB 51 1e-06 4D2O-A nrPDB 49 3e-06 5AQ7-A nrPDB 49 3e-06 5AQA-A nrPDB 49 3e-06 3OPP-A nrPDB 49 4e-06 4DXB-A nrPDB 48 9e-06 1E25-A nrPDB 45 5e-05 5NE2-A nrPDB 42 4e-04 3BFD-A nrPDB 41 8e-04 5KSC-A nrPDB 39 0.003 2JE5-A nrPDB 39 0.003 2Y2J-A nrPDB 39 0.004 5ZB7-A nrPDB 38 0.008 1PIO-A nrPDB 37 0.015 5FA7-A nrPDB 37 0.018 1ALQ-A nrPDB 37 0.019 3CJM-A nrPDB 36 0.035 5HW3-A nrPDB 35 0.044 1DY6-A nrPDB 35 0.061 2LCJ-A nrPDB 35 0.066 5KMU-A nrPDB 35 0.071 1YQS-A nrPDB 35 0.080 1HZO-A nrPDB 34 0.097 3C5M-A nrPDB 34 0.11 1BUL-A nrPDB 34 0.15 6MK6-A nrPDB 33 0.20 1W79-A nrPDB 33 0.21 3HLD-A nrPDB 33 0.23 5LWF-A nrPDB 33 0.24 3UF7-A nrPDB 32 0.39 3WRZ-A nrPDB 31 1.2 4EUZ-A nrPDB 30 1.5 4KQQ-A nrPDB 30 1.8 1Q2Q-A nrPDB 30 2.5 4QQW-A nrPDB 29 2.8 3UPP-A nrPDB 29 3.0 6NI1-A nrPDB 29 3.9 3ALF-A nrPDB 29 4.0 6NJK-A nrPDB 29 4.3 3ROH-A nrPDB 29 4.8 3TFX-A nrPDB 29 5.2 6MSD-E nrPDB 28 7.8 5IG0-A nrPDB 28 7.9 3QBD-A nrPDB 28 9.6 >1NZO-A nrPDB Length = 363 Score = 531 bits (1367), Expect = e-151, Method: Composition-based stats. Identities = 359/363 (98%), Positives = 360/363 (99%) Query: 30 DDLNIKTMIPGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKA 89 DDLNIKTMIPGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKA Sbjct: 1 DDLNIKTMIPGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKA 60 Query: 90 GKFKETDLVTIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMAD 149 GKFKETDLVTIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMAD Sbjct: 61 GKFKETDLVTIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMAD 120 Query: 150 FAAGSQDAFVGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEY 209 FAAGSQDAFVGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEY Sbjct: 121 FAAGSQDAFVGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEY 180 Query: 210 SIYKEKEFTFNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVM 269 SIYKEKEFTFNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVM Sbjct: 181 SIYKEKEFTFNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVM 240 Query: 270 GGRTFKGREAESKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTI 329 GGRTFKGREAESKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTI Sbjct: 241 GGRTFKGREAESKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTI 300 Query: 330 PRGRMKDLKASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEGNFFGK 389 PRGRMKDLKASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEGNF Sbjct: 301 PRGRMKDLKASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEGNFGDP 360 Query: 390 IID 392 +ID Sbjct: 361 VID 363 >5FSR-A nrPDB Length = 375 Score = 469 bits (1208), Expect = e-133, Method: Composition-based stats. Identities = 173/346 (50%), Positives = 238/346 (68%) Query: 39 PGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLV 98 P P+I A S++L+DY +G++L N +R+PASLTK+MT YV+ +A+ + + D+V Sbjct: 30 PQPPEIHAGSWVLMDYTTGQILTAGNEHQQRNPASLTKLMTGYVVDRAIDSHRITPDDIV 89 Query: 99 TIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAF 158 T+G DAWA NPVF GSSLMFLK G +V V L RG+ + SGNDACVA+AD+ AG Q F Sbjct: 90 TVGRDAWAKDNPVFVGSSLMFLKEGDRVSVRDLSRGLIVDSGNDACVALADYIAGGQRQF 149 Query: 159 VGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFT 218 V +MN+Y L LK+THF+TVHGLDA GQ+SSA D+A++ +A+I P Y +Y EK T Sbjct: 150 VEMMNNYAEKLHLKDTHFETVHGLDAPGQHSSAYDLAVLSRAIIHGEPEFYHMYSEKSLT 209 Query: 219 FNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKGRE 278 +NGI Q NRNGLLWD ++NVDG+KTGHT AG+NL+ASA +GQ RLI+ VMG + KGRE Sbjct: 210 WNGITQQNRNGLLWDKTMNVDGLKTGHTSGAGFNLIASAVDGQRRLIAVVMGADSAKGRE 269 Query: 279 AESKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTIPRGRMKDLK 338 E++KLL WG + F TV L GK+ +E +W+GD + LG +++ ++ +P+ + +K Sbjct: 270 EEARKLLRWGQQNFTTVQILHRGKKVGTERIWYGDKENIDLGTEQEFWMVLPKAEIPHIK 329 Query: 339 ASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEG 384 A Y L+ EL AP+ +Q VG I K + PLV L+ + EG Sbjct: 330 AKYTLDGKELTAPISAHQRVGEIELYDRDKQVAHWPLVTLESVGEG 375 >3ITA-A nrPDB Length = 352 Score = 463 bits (1192), Expect = e-131, Method: Composition-based stats. Identities = 224/345 (64%), Positives = 278/345 (80%) Query: 41 VPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTI 100 P +DA ++IL+DY SGKVLAE NAD + DPASLTK+MTSYV+GQA+KA K K TD+VT+ Sbjct: 8 APSVDARAWILMDYASGKVLAEGNADEKLDPASLTKIMTSYVVGQALKADKIKLTDMVTV 67 Query: 101 GNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVG 160 G DAWATGNP +GSS+MFLKPG QV V+ L +G+ +QSGNDAC+A+AD+ AGSQ++F+G Sbjct: 68 GKDAWATGNPALRGSSVMFLKPGDQVSVADLNKGVIIQSGNDACIALADYVAGSQESFIG 127 Query: 161 LMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFTFN 220 LMN Y LGL NT FQTVHGLDA GQ+S+ARDMAL+G+ALI DVP EY+I+KEKEFTFN Sbjct: 128 LMNGYAKKLGLTNTTFQTVHGLDAPGQFSTARDMALLGKALIHDVPEEYAIHKEKEFTFN 187 Query: 221 GIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKGREAE 280 IRQ NRN LLW ++LNVDG+KTG T AGYNLVASAT+G MRLIS V+G +T + R E Sbjct: 188 KIRQPNRNRLLWSSNLNVDGMKTGTTAGAGYNLVASATQGDMRLISVVLGAKTDRIRFNE 247 Query: 281 SKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTIPRGRMKDLKAS 340 S+KLLTWGFRFFETV P+K F ++ VWFGD +LG + +TIPRG++K+LKAS Sbjct: 248 SEKLLTWGFRFFETVTPIKPDATFVTQRVWFGDKSEVNLGAGEAGSVTIPRGQLKNLKAS 307 Query: 341 YVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEGN 385 Y L +L APL+K QVVGTI+FQL+GK+IEQRPL+V++ + EG Sbjct: 308 YTLTEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLIVMENVEEGG 352 >5TR7-A nrPDB Length = 341 Score = 448 bits (1152), Expect = e-126, Method: Composition-based stats. Identities = 204/345 (59%), Positives = 255/345 (73%), Gaps = 4/345 (1%) Query: 39 PGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLV 98 P PQI A+ Y+L+DY+SGKVLAE+ D + PASLTKMMTSYVIGQ +K G D V Sbjct: 1 PDAPQIAAKGYVLMDYHSGKVLAEKEMDTKLSPASLTKMMTSYVIGQEVKRGNISLNDDV 60 Query: 99 TIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAF 158 I +AWA F SS MF++ G V VS L RGI +QSGNDACVAMA+ AG++DAF Sbjct: 61 VISKNAWAKN---FPDSSKMFVEVGTTVKVSDLNRGIIIQSGNDACVAMAEHVAGTEDAF 117 Query: 159 VGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFT 218 V LMN++ ++LG+KN+HF HGLD YS+ D+AL+GQALIRDVP EY+IY E++FT Sbjct: 118 VDLMNAWASSLGMKNSHFTNSHGLDDPNLYSTPYDLALLGQALIRDVPEEYAIYSEQKFT 177 Query: 219 FNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKGRE 278 +NGI Q NRNGLLWD S+NVDGIKTGHT AGYNLV+SATEG MRL++ VMG R+ Sbjct: 178 YNGITQYNRNGLLWDKSMNVDGIKTGHTSGAGYNLVSSATEGNMRLVAVVMGTDNENARK 237 Query: 279 AESKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTIPRGRMKDLK 338 AESKKLL++GFRFFETV P K G+ F +E +W GD D +LGVDKD Y+T+PRG+ KDL Sbjct: 238 AESKKLLSYGFRFFETVAPHKAGETFVNETIWMGDKDTIALGVDKDTYVTLPRGQAKDLT 297 Query: 339 ASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPE 383 AS+VL +L APL+K +VGT+ +QL G I Q PL+ L+++ E Sbjct: 298 ASFVLE-KQLKAPLKKGDIVGTLYYQLAGNDIAQYPLLALEDVQE 341 >4K91-A nrPDB Length = 346 Score = 443 bits (1140), Expect = e-125, Method: Composition-based stats. Identities = 170/352 (48%), Positives = 230/352 (65%), Gaps = 8/352 (2%) Query: 35 KTMIPGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKE 94 ++M+P PQ+ A+SY+L+D SG+VL E N D R PASLTK+MT+Y+ + ++AG+ E Sbjct: 3 ESMVPAPPQLAAKSYVLMDGESGQVLVENNGDQRLPPASLTKLMTAYIATKEIEAGRIGE 62 Query: 95 TDLVTIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGS 154 DLVT+ AW T G S MF+K G QV VS L+ GI +QSGNDA VA+A+ AGS Sbjct: 63 NDLVTVSEHAWRT------GGSRMFIKVGSQVSVSDLLHGIIIQSGNDASVALAEHIAGS 116 Query: 155 QDAFVGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKE 214 +DAF +MN+ LGL N+HF GL YSSARDMA++ +A+I P+ Y+IY + Sbjct: 117 EDAFADMMNTTAQKLGLTNSHFMDATGLPNPDHYSSARDMAVLARAIIYGEPSHYAIYAQ 176 Query: 215 KEFTFNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTF 274 KEF +N I+Q NRN LLW + VDG+KTGHTD+AGY LVASA R+I+ V G + Sbjct: 177 KEFLWNNIKQPNRNLLLWRDK-TVDGLKTGHTDEAGYCLVASAVRDGQRMIAVVFGTNSE 235 Query: 275 KGREAESKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTIPRGRM 334 + R AE++KLLT+GFRFFE+ N K G E VW G G+ +D+ +T+PRG+M Sbjct: 236 QARAAETQKLLTYGFRFFESRNFYKKGTELTKGLVWKGSEHEVKAGLAEDLTMTLPRGQM 295 Query: 335 KDLKASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEGNF 386 + L+AS VL +L AP+Q+ QV+G + +LD K I LV L + EG F Sbjct: 296 QKLQASMVLE-PQLMAPIQQGQVIGKVEVKLDDKVIRSADLVALNAVEEGGF 346 >3A3J-A nrPDB Length = 344 Score = 432 bits (1112), Expect = e-122, Method: Composition-based stats. Identities = 191/344 (55%), Positives = 236/344 (68%), Gaps = 4/344 (1%) Query: 41 VPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTI 100 PQI A++Y+L+DYNSG +L N D R+ PASLTKMMTSYV+G A+K GK TD+VTI Sbjct: 4 PPQITAQTYVLMDYNSGAILTALNPDQRQYPASLTKMMTSYVVGVALKQGKIHNTDMVTI 63 Query: 101 GNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVG 160 G AW F SS MFL QV V+ L RG+ + SGNDA VA+A+ +G+ FV Sbjct: 64 GESAWGRN---FPDSSKMFLDLNTQVSVADLNRGVIVVSGNDATVALAEHISGNVPNFVE 120 Query: 161 LMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFTFN 220 MN YV GLKNT+F T HGLD QYSSARDMA+IG +IRD+P EY IY EK+FTFN Sbjct: 121 TMNKYVQQFGLKNTNFTTPHGLDDPNQYSSARDMAIIGAHIIRDLPEEYKIYSEKDFTFN 180 Query: 221 GIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASA-TEGQMRLISAVMGGRTFKGREA 279 I+Q NRNGLLWD ++NVDG+KTGHT +AGYNLVASA T MRLIS VMG T+KGRE Sbjct: 181 KIKQPNRNGLLWDKTINVDGMKTGHTSQAGYNLVASATTSNNMRLISVVMGVPTYKGREV 240 Query: 280 ESKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTIPRGRMKDLKA 339 ESKKLL WGF FET L+ GKE + + V++GD + LG D ++TIP+G+ ++KA Sbjct: 241 ESKKLLQWGFANFETFKTLEAGKEISEQRVYYGDKNSVKLGAFMDHFITIPKGKQSEVKA 300 Query: 340 SYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPE 383 Y L L APL K QV+G + + LDGK I L V+ ++ E Sbjct: 301 RYELADKNLQAPLAKGQVIGKVVYALDGKDIASANLQVMNDVGE 344 >6OSU-A nrPDB Length = 427 Score = 340 bits (872), Expect = 7e-94, Method: Composition-based stats. Identities = 125/411 (30%), Positives = 201/411 (48%), Gaps = 75/411 (18%) Query: 39 PGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLV 98 P ++DA +++ +DY +G +++E+N DVRR PASLTK+MTSY++ +KAG ++ Sbjct: 30 PANIELDAPAWVTMDYRTGDIVSEKNMDVRRAPASLTKIMTSYIVASEIKAGNLSWDTMI 89 Query: 99 TIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAF 158 I +A +T G S M++K G +V V L+ G+++ SGNDA +A+A++ G+ AF Sbjct: 90 PISENAAST------GGSKMYVKAGAKVSVRNLVTGMDVVSGNDATIALAEYIGGTTQAF 143 Query: 159 VGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFT 218 LMN A+G+ NTHF GL QY++A DMAL+ ++ I + P Y +Y +K Sbjct: 144 TDLMNQTAKAIGMNNTHFANPDGLPGGEQYTTAHDMALLARSYIYNFPEAYKVYDDKGLV 203 Query: 219 FNGIR----------------------------------------------------QLN 226 +N + Q N Sbjct: 204 WNATKQDSVSIADRKQCLPKFDRATGNVIESYTVKDLDDQAKDKCNKLFPKGDNFVLQNN 263 Query: 227 RNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKGREAESKKLLT 286 RN LL+ DG+KTGHTD AGY LV+SA + R IS V+G + R++ES KLL Sbjct: 264 RNRLLFTFD-GADGMKTGHTDAAGYCLVSSAKQDGERFISVVLGTTSSAKRDSESAKLLR 322 Query: 287 WGFRFFETVNPLKVGKEFASEPVWFGDSD--------RASLGVDKDVYLTIPRGRMKDLK 338 + +E V K A+ PV + + ++ ++++Y T+P+ + LK Sbjct: 323 YALSKYENVLLYK-----ANSPVTISADNIPNAKAGQKLTVASNQNIYKTVPKTYVPYLK 377 Query: 339 ASYVLNSSELHAPLQKNQVVGTINFQLDG--KTIEQRPLVVLQEIPEGNFF 387 N L+AP++ Q VG + L + I P+V + + + ++ Sbjct: 378 QGIEFN-PNLNAPIKTGQTVGNLVITLGDTKEEIASIPVVAMNNVSQKGWW 427 >1XP4-A nrPDB Length = 379 Score = 304 bits (778), Expect = 4e-83, Method: Composition-based stats. Identities = 88/357 (24%), Positives = 155/357 (43%), Gaps = 26/357 (7%) Query: 34 IKTMIPGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFK 93 + T + I A+ I ++ N+GK+L E++A + AS+TK++T Y++ +A++ G Sbjct: 2 VSTAVAQDFTIAAKHAIAVEANTGKILYEKDATQPVEIASITKLITVYLVYEALENGSIT 61 Query: 94 ETDLVTIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAG 153 + V I + + + M V +L+ + S N A +A+A+ AG Sbjct: 62 LSTPVDISDYPYQLTTNSEASNIPM---EARNYTVEELLEATLVSSANSAAIALAEKIAG 118 Query: 154 SQDAFVGLMNSYVNALGLKNTHFQTVHGLD----ADGQYS----------SARDMALIGQ 199 S+ FV +M + + G+++ GL+ D Y SA D+A++ + Sbjct: 119 SEKDFVDMMRAKLLEWGIQDATVVNTTGLNNETLGDNIYPGSKKDEENKLSAYDVAIVAR 178 Query: 200 ALIRDVPNEYSIYKEKEFTFNGIRQLNRNGLLWDNS---LNVDGIKTGHTDKAGYNLVAS 256 LI+ P I K+ TF G+ + N +L DG+KTG TDKAG + V + Sbjct: 179 NLIKKYPQVLEITKKPSSTFAGMTITSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGT 238 Query: 257 ATEGQMRLISAVMGG----RTFKGREAESKKLLTWGFRFFETVNPLKVGKEF--ASEPVW 310 E MR+I+ V+ R + L+ + F ++ G + + PV Sbjct: 239 TVEKGMRVITVVLNADHQDNNPYARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQ 298 Query: 311 FGDSDRASLGVDKDVYLTIPRGRMKDLKASYVLNSSELHAPLQKNQVVGTINFQLDG 367 G D +D+YL G + +S + APL+ VVG + ++ Sbjct: 299 DGKEDTVIAVAPEDIYLIERVGNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKD 355 >3HUM-A nrPDB Length = 453 Score = 264 bits (675), Expect = 4e-71, Method: Composition-based stats. Identities = 81/321 (25%), Positives = 141/321 (43%), Gaps = 39/321 (12%) Query: 55 NSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWATGN-PVFK 113 +G++L + N D + +PAS+TK+MT Y+ +A+ G+ D VT+ N + P Sbjct: 79 QTGQLLYQYNIDTKWNPASMTKLMTMYLTLEAVNKGQLSLDDTVTMTNKEYIMSTLPELS 138 Query: 114 GSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGLMNSYVNALGLKN 173 + L PG ++ L++ S N A + +A + + FV LMN+ A+G+KN Sbjct: 139 NTKLY---PGQVWTIADLLQITVSNSSNAAALILAKKVSKNTSDFVDLMNNKAKAIGMKN 195 Query: 174 THFQTVHGL--------------DADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFTF 219 THF G D + ++ARD A++ +I++ P K+ T Sbjct: 196 THFVNPTGAENSRLRSFAPTKYKDQERTVTTARDYAILDLHVIKETPKILDFTKQLAPTT 255 Query: 220 NGIRQLNRNGLLWDNS---LNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKG 276 + + N L DG+KTG +D A YN + G+ R+ +MG +K Sbjct: 256 HAVTYYTFNFSLEGAKMSLPGTDGLKTGSSDTANYNHTITTKRGKFRINQVIMGAGDYKN 315 Query: 277 REAESKK------LLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTIP 330 E ++ L+ F ++ V L G++ + ++ V+ D+Y +P Sbjct: 316 LGGEKQRNMMGNALMERSFDQYKYVKILSKGEQRINGKKYY---------VENDLYDVLP 366 Query: 331 RG-RMKDLKASYVLNSSELHA 350 KD K V+ ++HA Sbjct: 367 SDFSKKDYKL--VVEDGKVHA 385 >1TVF-A nrPDB Length = 369 Score = 261 bits (666), Expect = 5e-70, Method: Composition-based stats. Identities = 81/321 (25%), Positives = 141/321 (43%), Gaps = 39/321 (12%) Query: 55 NSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWATGN-PVFK 113 +G++L + N D + +PAS+TK+MT Y+ +A+ G+ D VT+ N + P Sbjct: 43 QTGQLLYQYNIDTKWNPASMTKLMTMYLTLEAVNKGQLSLDDTVTMTNKEYIMSTLPELS 102 Query: 114 GSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGLMNSYVNALGLKN 173 + L PG ++ L++ S N A + +A + + FV LMN+ A+G+KN Sbjct: 103 NTKLY---PGQVWTIADLLQITVSNSSNAAALILAKKVSKNTSDFVDLMNNKAKAIGMKN 159 Query: 174 THFQTVHGL--------------DADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFTF 219 THF G D + ++ARD A++ +I++ P K+ T Sbjct: 160 THFVNPTGAENSRLRSFAPTKYKDQERTVTTARDYAILDLHVIKETPKILDFTKQLAPTT 219 Query: 220 NGIRQLNRNGLLWDNS---LNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKG 276 + + N L DG+KTG +D A YN + G+ R+ +MG +K Sbjct: 220 HAVTYYTFNFSLEGAKMSLPGTDGLKTGSSDTANYNHTITTKRGKFRINQVIMGAGDYKN 279 Query: 277 REAESKK------LLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTIP 330 E ++ L+ F ++ V L G++ + ++ V+ D+Y +P Sbjct: 280 LGGEKQRNMMGNALMERSFDQYKYVKILSKGEQRINGKKYY---------VENDLYDVLP 330 Query: 331 RG-RMKDLKASYVLNSSELHA 350 KD K V+ ++HA Sbjct: 331 SDFSKKDYKL--VVEDGKVHA 349 >3MFD-A nrPDB Length = 334 Score = 253 bits (646), Expect = 1e-67, Method: Composition-based stats. Identities = 95/351 (27%), Positives = 165/351 (47%), Gaps = 25/351 (7%) Query: 40 GVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVT 99 + A+S I+ID SG+VL ++ +R AS+TK+MT+ + A+++GK +T V+ Sbjct: 3 AAIDVSAKSAIIIDGASGRVLYAKDEHQKRRIASITKIMTAVL---AIESGKMDQTVTVS 59 Query: 100 IGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFV 159 N V S ++L G +V + L+ G+ L+SGNDA VA+A+ GS D FV Sbjct: 60 --------ANAVRTEGSAIYLTEGQKVKLKDLVYGLMLRSGNDAAVAIAEHVGGSLDGFV 111 Query: 160 GLMNSYVNALGLKNTHFQTVHGL-DADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFT 218 +MN LG+KNT FQ HGL D + YS+A DMA++ + ++ + + I K + Sbjct: 112 YMMNQKAEQLGMKNTRFQNPHGLDDHENHYSTAYDMAILTKYAMK-LKDYQKISGTKIYK 170 Query: 219 FNGIRQL--NRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKG 276 + + N+N LL G KTG+T A LV++A++ + LI+ + Sbjct: 171 AETMESVWKNKNKLLTMLYPYSTGGKTGYTKLAKRTLVSTASKDGIDLIAVTI---NDPN 227 Query: 277 REAESKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTIPRGRMKD 336 + K+ + F ++T K G P G + + +D+ + ++ Sbjct: 228 DWDDHMKMFNYVFEHYQTYLIAKKGDI----PKLKGTFYESKAFIKRDITYLLTEEEKEN 283 Query: 337 LKASYVLNSSEL---HAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEG 384 +K + L + + +VG + + TI + P+ E + Sbjct: 284 VKINTTLLKPKKAWEKDASKIPDIVGHMEIMFNDATIAKVPIYYENERHQK 334 >4PPR-A nrPDB Length = 334 Score = 241 bits (615), Expect = 4e-64, Method: Composition-based stats. Identities = 70/263 (26%), Positives = 115/263 (43%), Gaps = 21/263 (7%) Query: 36 TMIPGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKET 95 P + AE++++ D +SG V+A ++ R PAS+ K++ + Sbjct: 50 GSAPAPGDVSAEAWLVADLDSGAVIAARDPHGRHRPASVIKVLVA-----------MASI 98 Query: 96 DLVTIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQ 155 + +T+ T + + + + G V+QL+ G+ + SGNDA A+A G Sbjct: 99 NTLTLNKSVAGTADDAAVEGTKVGVNTGGTYTVNQLLHGLLMHSGNDAAYALA-RQLGGM 157 Query: 156 DAFVGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEK 215 A + +N LG ++T T GLD G +SA D+ L + ++ P I + Sbjct: 158 PAALEKINLLAAKLGGRDTRVATPSGLDGPGMSTSAYDIGLFYRYAWQN-PVFADIVATR 216 Query: 216 EFTF------NGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVM 269 F F G N N LL+ N G KTG+TD AG V +A RL++ ++ Sbjct: 217 TFDFPGHGDHPGYELENDNQLLY-NYPGALGGKTGYTDDAGQTFVGAANRDGRRLMTVLL 275 Query: 270 -GGRTFKGREAESKKLLTWGFRF 291 G R ++ LL +GF Sbjct: 276 HGTRQPIPPWEQAAHLLDYGFNT 298 >6MUQ-A nrPDB Length = 283 Score = 234 bits (596), Expect = 6e-62, Method: Composition-based stats. Identities = 55/256 (21%), Positives = 110/256 (42%), Gaps = 21/256 (8%) Query: 40 GVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVT 99 ++ + S +++D + KV+ NAD AS+TK+MT+ V+ A K ++++ Sbjct: 10 APLELASGSAMVVDLQTNKVIYANNADEVVPIASITKLMTAMVVLDA----KLPLDEIIS 65 Query: 100 IGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFV 159 + VF ++ ++ ++ + S N A ++A G +AF+ Sbjct: 66 VDIHQTKEMKGVFSR-----VRVNSEISRKDMLLLALMSSENRAAASLAHHYPGGYNAFI 120 Query: 160 GLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQAL--------IRDVPNEYSI 211 MN+ +LG+ T + GL S+ARD+ + A + + + Sbjct: 121 NAMNAKAKSLGMTKTRYVEPTGLSI-NNVSTARDLTKLLIATKQYPLIGQLSTTTEKMAT 179 Query: 212 YKEKEFTFNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGG 271 ++E +T N N L++++ N+ KTG T++AG+ L G + V+ Sbjct: 180 FREPNYTLP---FRNTNHLVYNDKWNIQLTKTGFTNQAGHCLAMRTVIGNRPVALVVLDA 236 Query: 272 RTFKGREAESKKLLTW 287 A++ +L +W Sbjct: 237 FGKYTHFADANRLRSW 252 >5ZQC-A nrPDB Length = 276 Score = 232 bits (592), Expect = 2e-61, Method: Composition-based stats. Identities = 68/250 (27%), Positives = 115/250 (46%), Gaps = 11/250 (4%) Query: 44 IDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGND 103 + A + + +G+ L EQNAD ASL+K+MT++++ +A+ + + + + Sbjct: 33 LSANAAAVYSVENGEALYEQNADKVMPIASLSKLMTAFLVLEAVDNNELSWDEKLDLVR- 91 Query: 104 AWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGLMN 163 SL + V L + S NDA + D G+ F MN Sbjct: 92 -----LDDPSAVSLYAITQKRTWSVRDLYSAMLTMSANDAAETLGDRLDGA--DFPKEMN 144 Query: 164 SYVNALGLKN-THFQTVHGLDADGQ--YSSARDMALIGQALIRDVPNEYSIYKEKEFTFN 220 + LG+ + T F + GLD DG+ S+ +D+ L+ LI P + T + Sbjct: 145 NQAKKLGMSSKTTFVSASGLDVDGKSAVSTTKDLFLLSSKLISTHPEVLETTSKPTVTTD 204 Query: 221 GIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKGREAE 280 +L L + +DG+KTG TD+AGY + +A G R+IS V+ T + R + Sbjct: 205 KGAKLESTNDLLGSIQGLDGLKTGFTDEAGYCFIGTAERGGKRVISIVLDAGTAEKRFKD 264 Query: 281 SKKLLTWGFR 290 ++KL+ GF+ Sbjct: 265 TEKLMEVGFK 274 >6AZI-A nrPDB Length = 285 Score = 231 bits (590), Expect = 3e-61, Method: Composition-based stats. Identities = 62/260 (23%), Positives = 107/260 (41%), Gaps = 21/260 (8%) Query: 36 TMIPGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKET 95 T PQI + S +++D N+ KV+ + D+ R A +TK+MT+ V+ A Sbjct: 9 TTAAAQPQIASGSAMIVDLNTNKVIYASHPDLVRPIAXITKLMTAMVVLDAH----LPLD 64 Query: 96 DLVTIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQ 155 + + + V+ ++ ++ ++ + S N A ++A G Sbjct: 65 EKLKVDISHTPEMKGVYSR-----VRLNSEISRKNMLLLALMSSENRAAASLAHHYPGGY 119 Query: 156 DAFVGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQAL--------IRDVPN 207 DAF+ MN+ ALG+ NT F GL S+ARD+ + A + Sbjct: 120 DAFIRAMNAKAKALGMNNTRFVEPTGLSIHN-VSTARDLTKLLIASKQYPLIGQLSTTRE 178 Query: 208 EYSIYKEKEFTFNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISA 267 E + + +T N N L++ + N+ KTG T+ AG+ LV + Sbjct: 179 EMATFANPAYTLP---FRNTNHLVYRENWNIQLTKTGFTNAAGHCLVMRTVFNGKPVALV 235 Query: 268 VMGGRTFKGREAESKKLLTW 287 VM A++ +L TW Sbjct: 236 VMDAFGKYTHFADASRLRTW 255 >4RYE-A nrPDB Length = 269 Score = 231 bits (588), Expect = 6e-61, Method: Composition-based stats. Identities = 82/269 (30%), Positives = 122/269 (45%), Gaps = 22/269 (8%) Query: 31 DLNIKTMIPGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAG 90 D+ +P +P A+++I+ D +SG+VLA ++ +V PAS K++ + V A+ Sbjct: 6 DVQPAGSVP-IPDGPAQTWIVADLDSGQVLAGRDQNVAHPPASTIKVLLALV---ALDEL 61 Query: 91 KFKETDLVTIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADF 150 T + + D A N V +KPG QL+ G+ L SGNDA +A Sbjct: 62 DLNSTVVADVA-DTQAECNCV-------GVKPGRSYTARQLLDGLLLVSGNDAANTLAHM 113 Query: 151 AAGSQDAFVGLMNSYVNALGLKNTHFQTVHGLDADGQ--YSSARDMALIGQALIRDVPNE 208 G QD V MN+ LG +TH T GLD G S+A D+ +I +A + + P Sbjct: 114 L-GGQDVTVAKMNAKAATLGATSTHATTPSGLDGPGGSGASTAHDLVVIFRAAMAN-PVF 171 Query: 209 YSIYKEKEFTF---NGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLI 265 I E F NG + + L G KTG+T+ A V +A G RL+ Sbjct: 172 AQITAEPSAMFPSDNGEQLIVNQDELLQRYPGAIGGKTGYTNAARKTFVGAAARGGRRLV 231 Query: 266 SAVMGGRTFKGR---EAESKKLLTWGFRF 291 A+M G +G ++ L WGF Sbjct: 232 IAMMYGLVKEGGPTYWDQAATLFDWGFAL 260 >1SKF-A nrPDB Length = 262 Score = 211 bits (536), Expect = 5e-55, Method: Composition-based stats. Identities = 82/265 (30%), Positives = 121/265 (45%), Gaps = 21/265 (7%) Query: 42 PQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIG 101 P I A ++ +G L + AD RR S TK+MT+ V+ + VTI Sbjct: 4 PTIAAVGGYAMNNGTGTTLYTKAADTRRSTGSTTKIMTAKVV---LAQSNLNLDAKVTIQ 60 Query: 102 NDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFA-AGSQDA--- 157 + V +S L G +V V QL+ G+ L SG DA A+AD +GS A Sbjct: 61 K--AYSDYVVANNASQAHLIVGDKVTVRQLLYGLMLPSGCDAAYALADKYGSGSTRAARV 118 Query: 158 --FVGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSI---- 211 F+G MN+ LGL NTHF + G+ YS+ RD+ I + +++ + Sbjct: 119 KSFIGKMNTAATNLGLHNTHFDSFDGIGNGANYSTPRDLTKIASSAMKNSTFRTVVKTKA 178 Query: 212 YKEKEFTFNGI-----RQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLIS 266 Y K T G N NGLL + G+KTG +A Y LV +AT G +I Sbjct: 179 YTAKTVTKTGSIRTMDTWKNTNGLL-SSYSGAIGVKTGSGPEAKYCLVFAATRGGKTVIG 237 Query: 267 AVMGGRTFKGREAESKKLLTWGFRF 291 V+ + RE+++ K++ +GF Sbjct: 238 TVLASTSIPARESDATKIMNYGFAL 262 >4QY5-A nrPDB Length = 263 Score = 54.7 bits (130), Expect = 6e-08, Method: Composition-based stats. Identities = 43/254 (16%), Positives = 79/254 (31%), Gaps = 35/254 (13%) Query: 45 DAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDA 104 YI +D NSGK+L + R S K++ + + AG+ + + + Sbjct: 17 ARVGYIELDLNSGKILESFRPEERFPLTSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQND 76 Query: 105 WATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGLMNS 164 +PV + L GM V +L S N A + G + Sbjct: 77 LVEYSPVTEK----HLTDGM--TVRELCSAAITMSDNTAANLLLTTIGG-----PKELTD 125 Query: 165 YVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFTFNGIRQ 224 ++ +G K T + +G+ RD P + K T + Sbjct: 126 FLRQIGDKETRLDRIEPDLNEGKLGDLRD---------TTTPKAIASTLRKLLTGELLTL 176 Query: 225 LNRNGLL-WDNSLNVDGI--------------KTGHTDKAGYNLVASATEGQMRLISAVM 269 +R L+ W + V G K+G ++ ++A+ V+ Sbjct: 177 ASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVI 236 Query: 270 GGRTFKGREAESKK 283 + E + Sbjct: 237 YTTGSQATMDERNR 250 >2V1Z-A nrPDB Length = 291 Score = 52.4 bits (124), Expect = 3e-07, Method: Composition-based stats. Identities = 41/251 (16%), Positives = 79/251 (31%), Gaps = 35/251 (13%) Query: 48 SYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWAT 107 YI +D NSGK+L + R S K++ + + AG+ + + + Sbjct: 25 GYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRIDAGQEQLGRRIHYSQNDLVK 84 Query: 108 GNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGLMNSYVN 167 +PV + L GM V +L S N A + G + ++++ Sbjct: 85 YSPVTEK----HLTDGM--TVRELCSAAITMSDNTAANLLLTTIGG-----PKELTAFLH 133 Query: 168 ALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFTFNGIRQLNR 227 +G T + + RD + P + K T + +R Sbjct: 134 NMGDHVTRLDRWEPELNEAIPNDERDTTM---------PVAMATTLRKLLTGELLTLASR 184 Query: 228 NGLL-WDNSLNVDGI--------------KTGHTDKAGYNLVASATEGQMRLISAVMGGR 272 L+ W + V G K+G + ++A+ V+ Sbjct: 185 QQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGRRGSRGIIAALGPDGKPSRIVVIYTT 244 Query: 273 TFKGREAESKK 283 + + E + Sbjct: 245 GSRKKTDERNR 255 >3GMW-A nrPDB Length = 261 Score = 52.0 bits (123), Expect = 5e-07, Method: Composition-based stats. Identities = 41/254 (16%), Positives = 79/254 (31%), Gaps = 35/254 (13%) Query: 45 DAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDA 104 YI +D NSGK+L + R S K++ + + AG+ + + + Sbjct: 15 ARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQND 74 Query: 105 WATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGLMNS 164 +PV + L GM V +L S N A + G + + Sbjct: 75 LVEYSPVTEK----HLTDGM--TVRELCSAAITMSDNTAANLLLTTIGG-----PKELTA 123 Query: 165 YVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFTFNGIRQ 224 +++ +G T + + RD + P + K T + Sbjct: 124 FLHNMGDHVTRLDRWEPELNEAIPNDERDTTM---------PVAMATTLRKLLTGELLTL 174 Query: 225 LNRNGLL-WDNSLNVDGI--------------KTGHTDKAGYNLVASATEGQMRLISAVM 269 +R L+ W + V G K+G ++ ++A+ V+ Sbjct: 175 ASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVI 234 Query: 270 GGRTFKGREAESKK 283 + E + Sbjct: 235 YTTGSQATMDERNR 248 >5AQB-A nrPDB Length = 428 Score = 51.3 bits (121), Expect = 9e-07, Method: Composition-based stats. Identities = 46/256 (17%), Positives = 78/256 (30%), Gaps = 39/256 (15%) Query: 45 DAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDA 104 YI +D NSGK+L ++ R S K++ + I + AG+ + + + Sbjct: 182 ARVGYIELDLNSGKILESFRSEERFPMMSTFKVLLAGAILSRIDAGQEQLGRRIHYSQND 241 Query: 105 WATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAG--SQDAFVGLM 162 +PV + L GM V +L S N A + G AF+ M Sbjct: 242 LVEYSPVTEK----HLTDGM--TVRELASAAITMSDNTAANLLLTTIGGPKGLTAFLHNM 295 Query: 163 NSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFTFNGI 222 G T + + RD P + K T + Sbjct: 296 -------GDHVTRLDRWEPELNEAIPNDERD---------TTTPVAMATTLRKLLTGELL 339 Query: 223 RQLNRNGLL-WDNSLNVDGI--------------KTGHTDKAGYNLVASATEGQMRLISA 267 +R L+ W + V G K+G ++ +VA+ Sbjct: 340 TPASRQQLMDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIVAALGPDGKPSRIV 399 Query: 268 VMGGRTFKGREAESKK 283 V+ + E + Sbjct: 400 VIYTTGSQATMDELNR 415 >5AQ9-A nrPDB Length = 422 Score = 50.9 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 48/273 (17%), Positives = 82/273 (30%), Gaps = 41/273 (15%) Query: 30 DDLNIKTMIPGVPQ--IDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAM 87 DD+ + YI +D NSGK+L ++ R S K++ + I + Sbjct: 159 DDVGTLLQVAAAADQLGARVGYIELDLNSGKILESFRSEERFPMMSTFKVLLAGAILSRI 218 Query: 88 KAGKFKETDLVTIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAM 147 AG+ + + + +PV + L GM V +L S N A + Sbjct: 219 DAGQEQLGRRIHYSQNDLVEYSPVTEK----HLTDGM--TVRELASAAITMSDNTAANLL 272 Query: 148 ADFAAG--SQDAFVGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDV 205 G AF+ M G T + + RD Sbjct: 273 LTTIGGPKGLTAFLHNM-------GDHVTRLDRWEPELNEAIPNDERD---------TTT 316 Query: 206 PNEYSIYKEKEFTFNGIRQLNRNGLL-WDNSLNVDGI--------------KTGHTDKAG 250 P + K T + +R L+ W + V G K+G ++ Sbjct: 317 PVAMATTLRKLLTGELLTPASRQQLMDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGS 376 Query: 251 YNLVASATEGQMRLISAVMGGRTFKGREAESKK 283 +VA+ V+ + E + Sbjct: 377 RGIVAALGPDGKPSRIVVIYTTGSQATMDELNR 409 >4D2O-A nrPDB Length = 284 Score = 49.3 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 42/231 (18%), Positives = 77/231 (33%), Gaps = 31/231 (13%) Query: 64 NADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWATGNPVFKGSSLMFLKPG 123 N + S+ K+ + ++ + GK VT+ A S +M G Sbjct: 38 NPFEKFPMQSVFKLHLAMLVLHQVDQGKLDLNQSVTVNRAAVLQNTW----SPMMKDHQG 93 Query: 124 MQVPVS--QLIRGINLQSGNDACVAMADFAAGSQDAFVGLMNSYVNALGLKNTHFQTVHG 181 + V+ QL++ S N AC + + G Q +++Y+ +LG+K Sbjct: 94 DEFTVAVQQLLQYSVSHSDNVACDLLFELVGGPQ-----ALHAYIQSLGVKEAAVVANEA 148 Query: 182 ---LDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFTFNGIRQLNR-----NGLL-- 231 D QY + M Q L + + + + + + GLL Sbjct: 149 QMHADDQVQYQNWTSMKAAAQVLQKFEQKKQLSETSQALLWKWMVETTTGPQRLKGLLPA 208 Query: 232 ------WDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKG 276 + V KT T+ AG ++ L+ AV + + Sbjct: 209 GTIVAHKTGTSGVRAGKTAATNDAGVIMLP----DGRPLLVAVFVKDSAES 255 >5AQ7-A nrPDB Length = 418 Score = 49.3 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 48/268 (17%), Positives = 80/268 (29%), Gaps = 39/268 (14%) Query: 26 AAHADDLNIKTMIPGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQ 85 AA I + YI +D NSGK+L ++ R S K++ + I Sbjct: 153 AADQGHAEIAAKLVAARLKARVGYIELDLNSGKILESVRSEERFPMMSTFKVLLAGAILS 212 Query: 86 AMKAGKFKETDLVTIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACV 145 + AG+ + + + +PV + L GM V +L S N A Sbjct: 213 RIDAGQEQLGRRIHYSQNDLVEYSPVTEK----HLTDGM--TVRELASAAITMSDNTAAN 266 Query: 146 AMADFAAG--SQDAFVGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIR 203 + G AF+ M G T + + RD Sbjct: 267 LLLTTIGGPKGLTAFLHNM-------GDHVTRLDRWEPELNEAIPNDERD---------T 310 Query: 204 DVPNEYSIYKEKEFTFNGIRQLNRNGLL-WDNSLNVDGI--------------KTGHTDK 248 P + K T + +R L+ W + V G K+G ++ Sbjct: 311 TTPVAMATTLRKLLTGELLTPASRQQLMDWMEADKVAGPLLRSVLPAGWFIADKSGAGER 370 Query: 249 AGYNLVASATEGQMRLISAVMGGRTFKG 276 +VA+ V+ + Sbjct: 371 GSRGIVAALGPDGKPSRIVVIYTTGSQA 398 >5AQA-A nrPDB Length = 418 Score = 49.3 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 48/268 (17%), Positives = 80/268 (29%), Gaps = 39/268 (14%) Query: 26 AAHADDLNIKTMIPGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQ 85 AA I + YI +D NSGK+L ++ R S K++ + I Sbjct: 153 AADQGHAEIAAKLVAARLKARVGYIELDLNSGKILESVRSEERFPMMSTFKVLLAGAILS 212 Query: 86 AMKAGKFKETDLVTIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACV 145 + AG+ + + + +PV + L GM V +L S N A Sbjct: 213 RIDAGQEQLGRRIHYSQNDLVEYSPVTEK----HLTDGM--TVRELASAAITMSDNTAAN 266 Query: 146 AMADFAAG--SQDAFVGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIR 203 + G AF+ M G T + + RD Sbjct: 267 LLLTTIGGPKGLTAFLHNM-------GDHVTRLDRWEPELNEAIPNDERD---------T 310 Query: 204 DVPNEYSIYKEKEFTFNGIRQLNRNGLL-WDNSLNVDGI--------------KTGHTDK 248 P + K T + +R L+ W + V G K+G ++ Sbjct: 311 TTPVAMATTLRKLLTGELLTPASRQQLMDWMEADKVAGPLLRSVLPAGWFIADKSGAGER 370 Query: 249 AGYNLVASATEGQMRLISAVMGGRTFKG 276 +VA+ V+ + Sbjct: 371 GSRGIVAALGPDGKPSRIVVIYTTGSQA 398 >3OPP-A nrPDB Length = 286 Score = 49.0 bits (115), Expect = 4e-06, Method: Composition-based stats. Identities = 55/272 (20%), Positives = 85/272 (31%), Gaps = 29/272 (10%) Query: 12 RLALTTALCTAFISAAHADDLNIKTMIPGVPQIDAESYIL-IDYNSGKVLAEQNADVRRD 70 RL + + L T + A HA ++ + Q+ ++ +D SG+ L AD R Sbjct: 5 RLCIISLLATLPL-AVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFP 63 Query: 71 PASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQ 130 S K++ + + AG + + + S L GM V + Sbjct: 64 MMSTFKVVLCGAVLARVDAGDEQLERKI----HYRQQDLVDYSPVSEKHLADGM--TVGE 117 Query: 131 LIRGINLQSGNDACVAMADFAAG--SQDAFVGLMNSYVNALGLKNTHFQTVHGLDADGQY 188 L S N A + G AF+ + V L T L D Sbjct: 118 LCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDSWETELNEA--LPGD--- 172 Query: 189 SSARDMALIGQALIRDVPNEYSIYKEKEFTFNGIRQLNRNGLL-WDNSLNVDGIKTGHTD 247 ARD P + K T + ++ LL W V G Sbjct: 173 --ARD---------TTTPASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVL 221 Query: 248 KAGYNLVASATEG--QMRLISAVMGGRTFKGR 277 AG+ + G R I A++G R Sbjct: 222 PAGWFIADKTGAGERGARGIVALLGPNNKAER 253 >4DXB-A nrPDB Length = 637 Score = 47.8 bits (112), Expect = 9e-06, Method: Composition-based stats. Identities = 29/127 (22%), Positives = 48/127 (37%), Gaps = 8/127 (6%) Query: 45 DAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDA 104 YI +D NSGK+L + R S K++ + + AG+ + + + Sbjct: 398 ARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRIDAGQEQLGRRIHYSQND 457 Query: 105 WATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQD--AFVGLM 162 +PV + L GM V +L S N A + G ++ AF+ M Sbjct: 458 LVEYSPVTEK----HLTDGM--TVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNM 511 Query: 163 NSYVNAL 169 +V L Sbjct: 512 GDHVTRL 518 >1E25-A nrPDB Length = 282 Score = 45.5 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 22/116 (18%), Positives = 43/116 (37%), Gaps = 11/116 (9%) Query: 64 NADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWATGNPVFKGSSLMFLKPG 123 N + S+ K+ + ++ + GK V + + +M G Sbjct: 36 NPFEKFPMQSVFKLHLAMLVLHQVDQGKLDLNQTVIVNRAKVLQNTW----APIMKAYQG 91 Query: 124 MQ--VPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGLMNSYVNALGLKNTHFQ 177 + VPV QL++ S N AC + + G ++ Y+ ++G+K T Sbjct: 92 DEFSVPVQQLLQYSVSHSDNVACDLLFELVGG-----PAALHDYIQSMGIKETAVV 142 >5NE2-A nrPDB Length = 278 Score = 42.4 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 21/103 (20%), Positives = 34/103 (33%), Gaps = 7/103 (6%) Query: 51 LIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWATGNP 110 L+D SG+ + + D R S K M + + + V +G + P Sbjct: 37 LLDTASGRRIGHR-QDERFPMCSTFKSMLAATVLSQAERMPALLDRRVPVGEADLLSHAP 95 Query: 111 VFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAG 153 V + G + V L R + S N A + G Sbjct: 96 VTRR------HAGKDMTVRDLCRATIITSDNTAANLLFGVVGG 132 >3BFD-A nrPDB Length = 263 Score = 41.2 bits (95), Expect = 8e-04, Method: Composition-based stats. Identities = 24/130 (18%), Positives = 48/130 (36%), Gaps = 15/130 (11%) Query: 47 ESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWA 106 ++ ++ +VL AD R S +K+MT+ + + + +TI Sbjct: 21 GVALINTADNSQVLYR--ADERFAMCSTSKVMTAAAVLKQSETHDGILQQKMTIKKADLT 78 Query: 107 TGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGLMNSYV 166 NPV + G + +++L S N A + G G + ++ Sbjct: 79 NWNPVTEKY------VGNTMTLAELSAATLQYSDNTAMNKLLAHLGG-----PGNVTAFA 127 Query: 167 NALGLKNTHF 176 ++G +T F Sbjct: 128 RSIG--DTTF 135 >5KSC-A nrPDB Length = 261 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 41/257 (15%), Positives = 81/257 (31%), Gaps = 28/257 (10%) Query: 47 ESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWA 106 ++ ++ ++L AD R S +K+M + + + ++ K V I Sbjct: 19 GVALINTADNSQILYR--ADERFAMCSTSKVMAAAAVLKQSESDKHLLNQRVEIKKSDLV 76 Query: 107 TGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGLMNSYV 166 NP+ + + +++L S N A + G + ++ Sbjct: 77 NYNPIAEK------HVNGTMTLAELGAAALQYSDNTAMNKLIAHLGG-----PDKVTAFA 125 Query: 167 NALG-----LKNTHFQTVHGLDA-DGQYSSARDMALIGQALIRDVPNEYSIYKEKEFTFN 220 +LG L T + ++ MA + L + + T+ Sbjct: 126 RSLGDETFRLDRTAPTLNTAIPGDPRDTTTPLAMAQTLKNLTLG-KALAETQRAQLVTWL 184 Query: 221 GIRQLNRNGLLWDNSLN-VDGIKTGHTDKAGYNLVASA-TEGQMRLISAVMGGRTFKGRE 278 + + V G KTG D N +A E L+ + + E Sbjct: 185 KGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQPEQKAE 244 Query: 279 ------AESKKLLTWGF 289 A + K++T GF Sbjct: 245 NRNDILAAAAKIVTHGF 261 >2JE5-A nrPDB Length = 720 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 14/80 (17%) Query: 50 ILIDYNSGKVL-------AEQNA-----DVRRDPASLTKMMTSYVIGQAMKAGKFKETDL 97 +L+D +G +L ++N D +R PAS TK + +Y G A+ G + Sbjct: 354 VLMDNQTGAILGFVGGRNYQENQNNHAFDTKRSPASTTKPLLAY--GIAIDQGLMGSETI 411 Query: 98 VTIGNDAWATGNPVFKGSSL 117 ++ +A GNP+ +S Sbjct: 412 LSNYPTNFANGNPIMYANSK 431 >2Y2J-A nrPDB Length = 494 Score = 38.9 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 14/80 (17%) Query: 50 ILIDYNSGKVL-------AEQNA-----DVRRDPASLTKMMTSYVIGQAMKAGKFKETDL 97 +L+D +G +L ++N D +R PAS TK + +Y G A+ G + Sbjct: 128 VLMDNQTGAILGFVGGRNYQENQNNHAFDTKRSPASTTKPLLAY--GIAIDQGLMGSETI 185 Query: 98 VTIGNDAWATGNPVFKGSSL 117 ++ +A GNP+ +S Sbjct: 186 LSNYPTNFANGNPIMYANSK 205 >5ZB7-A nrPDB Length = 287 Score = 37.8 bits (86), Expect = 0.008, Method: Composition-based stats. Identities = 25/151 (16%), Positives = 47/151 (31%), Gaps = 11/151 (7%) Query: 47 ESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWA 106 ++ ++ ++L AD R S +K+M + + + + K V I Sbjct: 45 GVALINTADNSQILYR--ADERFPMCSTSKVMAAAAVLKQSETQKQLLNQPVEIKPADLV 102 Query: 107 TGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFA--AGSQDAFVGLMNS 164 NP+ + + +++L S N A + G AF + Sbjct: 103 NYNPIAEK------HVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGPGGVTAFARAIGD 156 Query: 165 YVNALGLKNTHFQTVHGLDADGQYSSARDMA 195 L T D ++ R MA Sbjct: 157 ETFRLDRTEPTLNTAIPGD-PRDTTTPRAMA 186 >1PIO-A nrPDB Length = 257 Score = 37.0 bits (84), Expect = 0.015, Method: Composition-based stats. Identities = 27/126 (21%), Positives = 48/126 (38%), Gaps = 14/126 (11%) Query: 50 ILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWATGN 109 +D SGK + + N+D R AS +K + S ++ + + K + V I D + Sbjct: 18 YALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVPYNKLNK--KVHINKDDIVAYS 74 Query: 110 PVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGLMNSYVNAL 169 P+ + G + + LI S N A + G + + + L Sbjct: 75 PILEKY------VGKDITLKALIEASMTYSDNTANNKIIKEIGG-----IKKVKQRLKEL 123 Query: 170 GLKNTH 175 G K T+ Sbjct: 124 GDKVTN 129 >5FA7-A nrPDB Length = 266 Score = 36.6 bits (83), Expect = 0.018, Method: Composition-based stats. Identities = 23/156 (14%), Positives = 46/156 (29%), Gaps = 9/156 (5%) Query: 47 ESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWA 106 ++ ++ ++L AD R S +K+M + + + ++ V I Sbjct: 24 GVALINTADNSQILYR--ADERFAMCSTSKVMAAAAVLKKSESEPNLLNQRVEIKKSDLV 81 Query: 107 TGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGLMNSYV 166 NP+ + + +++L S N A + G Sbjct: 82 NYNPIAEK------HVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGPASVTAFARQLGD 135 Query: 167 NALGLKNTHFQTVHGLDA-DGQYSSARDMALIGQAL 201 L T + +S R MA + L Sbjct: 136 ETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNL 171 >1ALQ-A nrPDB Length = 266 Score = 36.6 bits (83), Expect = 0.019, Method: Composition-based stats. Identities = 27/126 (21%), Positives = 48/126 (38%), Gaps = 14/126 (11%) Query: 50 ILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWATGN 109 +D SGK + + N+D R AS +K + S ++ + + K + V I D + Sbjct: 63 YALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVPYNKLNK--KVHINKDDIVAYS 119 Query: 110 PVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGLMNSYVNAL 169 P+ + G + + LI S N A + G + + + L Sbjct: 120 PILEKY------VGKDITLKALIEASMTYSDNTANNKIIKEIGG-----IKKVKQRLKEL 168 Query: 170 GLKNTH 175 G K T+ Sbjct: 169 GDKVTN 174 >3CJM-A nrPDB Length = 282 Score = 35.9 bits (81), Expect = 0.035, Method: Composition-based stats. Identities = 29/192 (15%), Positives = 66/192 (34%), Gaps = 21/192 (10%) Query: 52 IDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWATGNPV 111 +D +G+ + AS K+ + ++ + +G+ K TDL+ + Sbjct: 57 LDLETGEQRSVNGQHE-FYTASTIKVPLTMLVADTVASGQKKWTDLI-----PYNAEEDY 110 Query: 112 FKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGLMNSYVNALGL 171 +G+ ++ + P+ L S N A + D G A + Y++ Sbjct: 111 EEGTGIIAYNIQPEYPLKTLQEYAITYSDNIAKNMLYDTLGGDAKAKREMYQRYLHK--- 167 Query: 172 KNTHFQTVHGLDADGQYSSARDMALIGQALI--RDVPNEYSIYK--EKEFTFNGIRQLNR 227 T ++ Q+SS + ++ + P+ +IY ++ + Sbjct: 168 ------TPS-IEEP-QFSSEDALVILQKLYTEKATKPDYQAIYDSMKQSVFHERMETPTT 219 Query: 228 NGLLWDNSLNVD 239 G + + D Sbjct: 220 QGKVAHKIGSYD 231 >5HW3-A nrPDB Length = 269 Score = 35.5 bits (80), Expect = 0.044, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 41/103 (39%), Gaps = 6/103 (5%) Query: 51 LIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWATGNP 110 ID SG+ L + AD R S K + + I + +G + LV +P Sbjct: 27 AIDTGSGRTLGHR-ADERFLMCSTFKGLLAAQILARVDSGSERLDRLVHYTEKDLIFTSP 85 Query: 111 VFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAG 153 V + + G + + L R + ++S N A + + A G Sbjct: 86 V----TKANVAQGA-MSIEALCRAVLVESDNTAAILLMRSAGG 123 >1DY6-A nrPDB Length = 267 Score = 35.1 bits (79), Expect = 0.061, Method: Composition-based stats. Identities = 18/114 (15%), Positives = 33/114 (28%), Gaps = 7/114 (6%) Query: 51 LIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWATGNP 110 ID SG +D R S K + + + ++ K V + +P Sbjct: 25 AIDTGSGNT-FGYRSDERFPLCSSFKGFLAAAVLERVQQKKLDINQKVKYESRDLEYHSP 83 Query: 111 VFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGLMNS 164 + G + + + S N A + + G + M S Sbjct: 84 ITTKYK------GSGMTLGDMASAALQYSDNGATNIIMERFLGGPEGMTKFMRS 131 >2LCJ-A nrPDB Length = 185 Score = 34.7 bits (78), Expect = 0.066, Method: Composition-based stats. Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 9/93 (9%) Query: 50 ILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWATGN 109 ID +GKV+ DV + PA T ++I ++ G+ ET T+ + N Sbjct: 50 YSIDLETGKVVLTDIEDVIKAPA------TDHLIRFELEDGRSFET---TVDHPVLVYEN 100 Query: 110 PVFKGSSLMFLKPGMQVPVSQLIRGINLQSGND 142 F +K G +V VS+L S D Sbjct: 101 GRFIEKRAFEVKEGDKVLVSELELVEQSSSSQD 133 >5KMU-A nrPDB Length = 290 Score = 34.7 bits (78), Expect = 0.071, Method: Composition-based stats. Identities = 19/118 (16%), Positives = 38/118 (32%), Gaps = 10/118 (8%) Query: 47 ESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWA 106 ++ ++ +VL D R S +K+M + + + + K V I Sbjct: 48 GVALIDTADNTQVLYRG--DERFPMCSTSKVMAAAAVLKQSETQKQLLNQPVEIKPADLV 105 Query: 107 TGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFA--AGSQDAFVGLM 162 NP+ + + +++L S N A + G AF + Sbjct: 106 NYNPIAEK------HVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGPGGVTAFARAI 157 >1YQS-A nrPDB Length = 349 Score = 34.7 bits (78), Expect = 0.080, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 34/96 (35%), Gaps = 18/96 (18%) Query: 38 IPGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDL 97 + I S + D +G+ + + R S+TK ++ V+ Q + GK Sbjct: 30 VDDNGTIHQLSEGVADRATGRAITTTD---RFRVGSVTKSFSAVVLLQLVDEGKLDLDAS 86 Query: 98 VTIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLIR 133 V + L L P ++ V Q++ Sbjct: 87 V---------------NTYLPGLLPDDRITVRQVMS 107 >1HZO-A nrPDB Length = 271 Score = 34.3 bits (77), Expect = 0.097, Method: Composition-based stats. Identities = 45/220 (20%), Positives = 71/220 (32%), Gaps = 14/220 (6%) Query: 62 EQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWATGNPVFKGSSLMFLK 121 + R AS +K+M + +A + +TI +P+ + L Sbjct: 35 TYRGEERFAMASTSKVMAVAAVLKASEKQAGLLDKNITIKKSDLVAYSPITEK----HLT 90 Query: 122 PGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQD--AFVGLMNSYVNALGLKNTHFQTV 179 GM +++L S N A + D+ G F +N L K T Sbjct: 91 TGM--TLAELSAATLQYSDNTAMNKILDYLGGPAKVTQFARSINDVTYRLDRKEPELNTA 148 Query: 180 -HGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFTFNGIRQLNRNGLLWDNSLN- 237 HG +S MA QAL +++ T+ N + + Sbjct: 149 IHG--DPRDTTSPIAMAKSLQALTLGD-ALGQSQRQQLVTWLKGNTTGDNSIKAGLPKHW 205 Query: 238 VDGIKTGHTDKAGYNLVASA-TEGQMRLISAVMGGRTFKG 276 V G KTG D N +A E LI V + + Sbjct: 206 VVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQQEQN 245 >3C5M-A nrPDB Length = 396 Score = 34.3 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 22/111 (19%), Positives = 42/111 (37%), Gaps = 8/111 (7%) Query: 107 TGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGS--QDAFVGLMNS 164 NP + + + P +S + + G DA V +AD + + D F+ ++N+ Sbjct: 268 KANPETLENEEVMVMPPCSHLMSNFDGSLMVGDGCDAPVDVADADSYNIENDPFLYVLNT 327 Query: 165 YVNALGLKNTHFQTVHGLDADGQYS------SARDMALIGQALIRDVPNEY 209 + H + LD D Q + + D ++ + VP Y Sbjct: 328 KAKSAQKLCKHSTSWDVLDGDRQITHPHPSFTPNDDGVLFTSDFEGVPAIY 378 >1BUL-A nrPDB Length = 265 Score = 33.5 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 17/115 (14%), Positives = 33/115 (28%), Gaps = 7/115 (6%) Query: 50 ILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWATGN 109 +D SGK A+ R S K + + + + + +V + + Sbjct: 22 YALDTGSGKS-FSYRANERFPLCSSFKGFLAAAVLKGSQDNRLNLNQIVNYNTRSLEFHS 80 Query: 110 PVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGLMNS 164 P+ + G + S N A + + G + M S Sbjct: 81 PITTKYKDNGMSLG------DMAAAALQYSDNGATNIILERYIGGPEGMTKFMRS 129 >6MK6-A nrPDB Length = 265 Score = 33.2 bits (74), Expect = 0.20, Method: Composition-based stats. Identities = 18/115 (15%), Positives = 31/115 (26%), Gaps = 7/115 (6%) Query: 50 ILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWATGN 109 I+ SGK A+ R S K + + K + + Sbjct: 21 YAINTGSGKA-YSYRANERFPLCSSFKAFLAAAVL------KMDQDSPGVLLEKVNYHNR 73 Query: 110 PVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGLMNS 164 + S + + V +L S N A + + + MNS Sbjct: 74 TMEPHSPITEKFQSQGMAVGELAAATLQYSDNGAANLLMEKYIKGPEGMTQFMNS 128 >1W79-A nrPDB Length = 489 Score = 33.2 bits (74), Expect = 0.21, Method: Composition-based stats. Identities = 9/48 (18%), Positives = 22/48 (45%) Query: 43 QIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAG 90 + +++D +G+ L ++ + PAS K+ T+ + + A Sbjct: 19 EGAVSGVVVVDTATGEELYSRDGGEQLLPASNMKLFTAAAALEVLGAD 66 >3HLD-A nrPDB Length = 432 Score = 33.2 bits (74), Expect = 0.23, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 29/70 (41%), Gaps = 3/70 (4%) Query: 66 DVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVT--IGNDAWATGNPVFKGSSLMFLKPG 123 D AS TK++T+ ++ Q M+ G + V + + + F + L+ Sbjct: 88 DTPCRLASATKLLTTIMVLQCMERGLVDLDETVDRLLPDLSAMPVLEGFDDAGNARLRER 147 Query: 124 M-QVPVSQLI 132 ++ + L+ Sbjct: 148 RGKITLRHLL 157 >5LWF-A nrPDB Length = 273 Score = 33.2 bits (74), Expect = 0.24, Method: Composition-based stats. Identities = 24/115 (20%), Positives = 40/115 (34%), Gaps = 10/115 (8%) Query: 43 QIDAESYI-LIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIG 101 Q DA+ I +D + + + D R AS K +T V+ Q + +T Sbjct: 13 QFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKSIEDLNQ--RITYT 69 Query: 102 NDAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQD 156 D NP+ + + GM + +L S N A + G + Sbjct: 70 RDDLVNYNPITEK----HVDTGM--TLKELADASLRYSDNAAQNLILKQIGGPES 118 >3UF7-A nrPDB Length = 237 Score = 32.4 bits (72), Expect = 0.39, Method: Composition-based stats. Identities = 19/70 (27%), Positives = 27/70 (38%), Gaps = 3/70 (4%) Query: 184 ADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFTFNGIRQLNRNGLLWDNSLNVDGIKT 243 GQ A +A + I P+ ++YKE E T G + N L V + T Sbjct: 68 GPGQ---AHGLAFSVRPGIAIPPSLLNMYKELENTIPGFTRPNHGYLESWARQGVLLLNT 124 Query: 244 GHTDKAGYNL 253 T +AG Sbjct: 125 VLTVRAGQAH 134 >3WRZ-A nrPDB Length = 367 Score = 30.8 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 43/231 (18%), Positives = 73/231 (31%), Gaps = 51/231 (22%) Query: 19 LCTAFISAAHADDLNIKTMIPGVPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMM 78 + + + A + I + P I Y D +G + + D + SL+K + Sbjct: 16 IVASLMEAQQIPGMAIALVRPEGTTIS--HYGAADRETGTPV---DDDTLFEIGSLSKTL 70 Query: 79 TSYVIGQAMKAGKFKETDLV---------TIGNDAWATGNPVFKGSSLMFLKPGMQVPVS 129 T+ + A GK V + +D G L P + Sbjct: 71 TATLASLAEVEGKLDFDAPVSRYLPELEGSAFDDISGLNLGTHTGGGLPLFVPDEVTDRA 130 Query: 130 QLIR-----------GINLQSGNDACVAMADFAAGSQDA-FVGLMNSYVNA-LGLKNTHF 176 L+ G + N + A S D FV M + V A LG+++T + Sbjct: 131 SLMAWYREWQPTEPIGESRTYSNLGIGLLGLETAASLDGEFVPTMRAKVLAPLGMQDTWY 190 Query: 177 QTVH--------GLDADGQ----------------YSSARDMALIGQALIR 203 G D DGQ ++A D+A + +A + Sbjct: 191 DVPEARMADYAMGEDKDGQPTRVSPGVLDDEAYGIKTTAADLAKLVRANLH 241 >4EUZ-A nrPDB Length = 283 Score = 30.5 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 20/115 (17%), Positives = 35/115 (30%), Gaps = 7/115 (6%) Query: 50 ILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWATGN 109 ID S K A+ R + K + + + + + N + Sbjct: 26 YAIDTGSNKT-FGYRANERFPLCASFKGFLAAAVLSKSQQQEGLLNQRIRYDNRVMEPHS 84 Query: 110 PVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVGLMNS 164 PV + + GM V++L S N A + + G + M S Sbjct: 85 PVTEKQ----ITTGM--TVAELSAATLQYSDNGAANLLLEKLIGGPEGMTSFMRS 133 >4KQQ-A nrPDB Length = 564 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 25/118 (21%), Positives = 46/118 (38%), Gaps = 34/118 (28%) Query: 46 AESYILIDYNSGKVLA-----EQNADVRRD----------------PASLTKMMTSYVIG 84 A S +++D +G++LA N + RR+ P S K + + Sbjct: 231 AGSLVIMDVKTGEILAMTNQPTYNPNNRRNLQPAAMRNRAMIDVFEPGSTVK---PFSMS 287 Query: 85 QAMKAGKFKETDLVTIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQL-IRGINLQSGN 141 A+ +G++K +D+V + G + S QL + GI ++S N Sbjct: 288 AALASGRWKPSDIVDVYPGTLQIGRYTIRDVSR---------NSRQLDLTGILIKSSN 336 >1Q2Q-A nrPDB Length = 363 Score = 29.7 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 15/35 (42%) Query: 65 ADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVT 99 + S++K T + G A+ G+ D VT Sbjct: 55 PQTLFELGSISKTFTGVLGGDAIARGEISLDDPVT 89 >4QQW-A nrPDB Length = 964 Score = 29.3 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 34/86 (39%), Gaps = 3/86 (3%) Query: 14 ALTTALCTAFISAAHADDLNIKTMIPGVPQIDAESYILIDYNSGKVLAEQNADVRRDPAS 73 ++ +L A++ A N P V ++ ++ +D GKV + D A+ Sbjct: 508 SIANSLVKAYLEGARGRRWNRSEPQP-VSEVSYPGWLHVDARIGKVTRSSDVD-PLPIAT 565 Query: 74 LT-KMMTSYVIGQAMKAGKFKETDLV 98 K + ++ +K G + ++ Sbjct: 566 TPRKPLEVRLVDVPVKEGALNRSTVL 591 >3UPP-A nrPDB Length = 462 Score = 29.3 bits (64), Expect = 3.0, Method: Composition-based stats. Identities = 39/218 (17%), Positives = 66/218 (30%), Gaps = 24/218 (11%) Query: 13 LALTTALCTAFISAAHADDLNIKTMIPGVPQIDAESYILIDYNSGKVLAEQNADVRRDPA 72 L +T A +S+ D + P++ A+++ + N L + P Sbjct: 136 LEPSTGKILALVSSPSYD---PNLLASHNPEVQAQAWQRLGDNPASPLTNRAISETYPPG 192 Query: 73 SLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWATGNPVFKGSSLMFLKPGMQVPVSQLI 132 S K++T+ A + T TI + + G + VS + Sbjct: 193 STFKVITTAAALAAGATETEQLTAAPTIPLP-----GSTAQLENYGGAPCGDEPTVS--L 245 Query: 133 RGINLQSGNDACVAMADFAAGSQDAFVGLMNSYVNALGLKN----THFQTVHGLDADGQY 188 R ++S N A V + + S A GL + T Q Sbjct: 246 REAFVKSCNTAFVQLGIRTG------ADALRSMARAFGLDSPPRPTPLQVAESTVGPIPD 299 Query: 189 SSARDMALIGQALIRDVP----NEYSIYKEKEFTFNGI 222 S+A M IGQ + P + T Sbjct: 300 SAALGMTSIGQKDVALTPLANAEIAATIANGGITMRPY 337 >6NI1-A nrPDB Length = 275 Score = 28.9 bits (63), Expect = 3.9, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 37/104 (35%), Gaps = 9/104 (8%) Query: 50 ILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGNDAWATGN 109 ID S K + + R AS K++ + + + K K +++ D T + Sbjct: 36 YAIDIGSNKTI-AYRPNERFAYASTYKVLAAAAVLK--KNSIEKLNEVIHYSKDDLVTYS 92 Query: 110 PVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAG 153 P+ + L GM + ++ S N A + G Sbjct: 93 PITEK----HLDTGM--SLKEISEAAIRYSDNTAGNILLQQLGG 130 >3ALF-A nrPDB Length = 353 Score = 28.9 bits (63), Expect = 4.0, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 22/60 (36%), Gaps = 9/60 (15%) Query: 140 GNDACVAMADFAAGSQDAFVGLMNSYVNALGLKNTHFQTVHGLDADGQYS-SARDMALIG 198 N + S+ +F+ LG HGLD D +Y SA DM +G Sbjct: 77 ANSTAYGIMARQPNSRKSFIDSSIRLARQLG--------FHGLDLDWEYPLSAADMTNLG 128 >6NJK-A nrPDB Length = 367 Score = 28.9 bits (63), Expect = 4.3, Method: Composition-based stats. Identities = 7/38 (18%), Positives = 14/38 (36%) Query: 62 EQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVT 99 D + S++K+ T+ + A G V+ Sbjct: 56 AATPDTIFELGSISKIFTATLAALAEDRGMLDLDAPVS 93 >3ROH-A nrPDB Length = 329 Score = 28.5 bits (62), Expect = 4.8, Method: Composition-based stats. Identities = 14/51 (27%), Positives = 18/51 (35%), Gaps = 6/51 (11%) Query: 150 FAAGSQDAFVGLMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQA 200 + S + V NS G+K F T G SA D L Q+ Sbjct: 185 YTQKSYVSEVDKQNSKSVKWGVKANEFVTPDG------KKSAHDRYLFVQS 229 >3TFX-A nrPDB Length = 259 Score = 28.5 bits (62), Expect = 5.2, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 18/49 (36%) Query: 164 SYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIY 212 + AL F TVH L SA+D + G VP ++ Sbjct: 74 NGAKALAKLGITFTTVHALGGSQMIKSAKDGLIAGTPAGHSVPKLLAVT 122 >6MSD-E nrPDB Length = 403 Score = 28.2 bits (61), Expect = 7.8, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 21/42 (50%) Query: 324 DVYLTIPRGRMKDLKASYVLNSSELHAPLQKNQVVGTINFQL 365 D L R ++K+L Y + ++L A Q+VG + QL Sbjct: 37 DGRLKELREQLKELTKQYEKSENDLKALQSVGQIVGEVLKQL 78 >5IG0-A nrPDB Length = 148 Score = 27.8 bits (60), Expect = 7.9, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 30/72 (41%), Gaps = 2/72 (2%) Query: 233 DNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKGREAESKK-LLTWGFRF 291 + S N D +KT D A +A +R++ V R E++ + F+F Sbjct: 72 NRSPNADKMKTTLHDPAVQMFGDTAIVTALRVVQFVADDGPKTTRYEETRVWVKDAAFKF 131 Query: 292 -FETVNPLKVGK 302 ++ V+ + G Sbjct: 132 GWKLVHFHRSGA 143 >3QBD-A nrPDB Length = 368 Score = 27.8 bits (60), Expect = 9.6, Method: Composition-based stats. Identities = 10/26 (38%), Positives = 11/26 (42%) Query: 231 LWDNSLNVDGIKTGHTDKAGYNLVAS 256 L G KTG AG NLV + Sbjct: 139 LLGMVDAAVGGKTGINTDAGKNLVGA 164 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.130 0.328 Lambda K H 0.267 0.0402 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,823,149 Number of Sequences: 36641 Number of extensions: 520487 Number of successful extensions: 1619 Number of sequences better than 10.0: 69 Number of HSP's better than 10.0 without gapping: 60 Number of HSP's successfully gapped in prelim test: 34 Number of HSP's that attempted gapping in prelim test: 1466 Number of HSP's gapped (non-prelim): 96 length of query: 403 length of database: 10,336,785 effective HSP length: 99 effective length of query: 304 effective length of database: 6,709,326 effective search space: 2039635104 effective search space used: 2039635104 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 60 (27.7 bits)