BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P0ABI8 (663 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1FFT-A nrPDB 1338 0.0 6HWH-V nrPDB 417 e-117 6ADQ-F nrPDB 409 e-114 2YEV-A nrPDB 358 4e-99 3ASN-A nrPDB 343 1e-94 5Z62-A nrPDB 342 3e-94 3HB3-A nrPDB 336 2e-92 3FYE-A nrPDB 331 8e-91 6HU9-a nrPDB 330 1e-90 3EH4-A nrPDB 55 9e-08 1BW0-A nrPDB 31 2.2 4NMY-A nrPDB 30 2.9 4IA5-A nrPDB 28 8.8 >1FFT-A nrPDB Length = 663 Score = 1338 bits (3462), Expect = 0.0, Method: Compositional matrix adjust. Identities = 663/663 (100%), Positives = 663/663 (100%) Query: 1 MFGKLSLDAVPFHEPIVMVTIAGIILGGLALVGLITYFGKWTYLWKEWLTSVDHKRLGIM 60 MFGKLSLDAVPFHEPIVMVTIAGIILGGLALVGLITYFGKWTYLWKEWLTSVDHKRLGIM Sbjct: 1 MFGKLSLDAVPFHEPIVMVTIAGIILGGLALVGLITYFGKWTYLWKEWLTSVDHKRLGIM 60 Query: 61 YIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQIFTAHGVIMIFFVAMPFVI 120 YIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQIFTAHGVIMIFFVAMPFVI Sbjct: 61 YIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQIFTAHGVIMIFFVAMPFVI 120 Query: 121 GLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSLGVGEFAQTGWLAYPPLSGIE 180 GLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSLGVGEFAQTGWLAYPPLSGIE Sbjct: 121 GLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSLGVGEFAQTGWLAYPPLSGIE 180 Query: 181 YSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGMTMFKMPVFTWASLCANVLII 240 YSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGMTMFKMPVFTWASLCANVLII Sbjct: 181 YSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGMTMFKMPVFTWASLCANVLII 240 Query: 241 ASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAWGHPEVYILILPVFGVFSE 300 ASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAWGHPEVYILILPVFGVFSE Sbjct: 241 ASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAWGHPEVYILILPVFGVFSE 300 Query: 301 IAATFSRKRLFGYTSLVWATVCITVLSFIVWLHHFFTMGAGANVNAFFGITTMIIAIPTG 360 IAATFSRKRLFGYTSLVWATVCITVLSFIVWLHHFFTMGAGANVNAFFGITTMIIAIPTG Sbjct: 301 IAATFSRKRLFGYTSLVWATVCITVLSFIVWLHHFFTMGAGANVNAFFGITTMIIAIPTG 360 Query: 361 VKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTGVLLAVPGADFVLHNSLFLIAHF 420 VKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTGVLLAVPGADFVLHNSLFLIAHF Sbjct: 361 VKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTGVLLAVPGADFVLHNSLFLIAHF 420 Query: 421 HNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFWFWIIGFFVAFMPLYALGFMGMT 480 HNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFWFWIIGFFVAFMPLYALGFMGMT Sbjct: 421 HNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFWFWIIGFFVAFMPLYALGFMGMT 480 Query: 481 RRLSQQIDPQFHTMLMIAASGAVLIALGILCLVIQMYVSIRDRDQNRDLTGDPWGGRTLE 540 RRLSQQIDPQFHTMLMIAASGAVLIALGILCLVIQMYVSIRDRDQNRDLTGDPWGGRTLE Sbjct: 481 RRLSQQIDPQFHTMLMIAASGAVLIALGILCLVIQMYVSIRDRDQNRDLTGDPWGGRTLE 540 Query: 541 WATSSPPPFYNFAVVPHVHERDAFWEMKEKGEAYKKPDHYEEIHMPKNSGAGIVIAAFST 600 WATSSPPPFYNFAVVPHVHERDAFWEMKEKGEAYKKPDHYEEIHMPKNSGAGIVIAAFST Sbjct: 541 WATSSPPPFYNFAVVPHVHERDAFWEMKEKGEAYKKPDHYEEIHMPKNSGAGIVIAAFST 600 Query: 601 IFGFAMIWHIWWLAIVGFAGMIITWIVKSFDEDVDYYVPVAEIEKLENQHFDEITKAGLK 660 IFGFAMIWHIWWLAIVGFAGMIITWIVKSFDEDVDYYVPVAEIEKLENQHFDEITKAGLK Sbjct: 601 IFGFAMIWHIWWLAIVGFAGMIITWIVKSFDEDVDYYVPVAEIEKLENQHFDEITKAGLK 660 Query: 661 NGN 663 NGN Sbjct: 661 NGN 663 >6HWH-V nrPDB Length = 583 Score = 417 bits (1072), Expect = e-117, Method: Compositional matrix adjust. Identities = 236/550 (42%), Positives = 337/550 (61%), Gaps = 17/550 (3%) Query: 40 KWTYLWKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHY 99 +WT L+K +T+ DHK +G+MY++ + G A+++R++ A+ FL Y Sbjct: 24 RWTLLYK-LVTTTDHKLIGMMYVVACFIFFFIGGLMALLLRTELAVPGLQ---FLSNEQY 79 Query: 100 DQIFTAHGVIMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGV-ILVNV 158 +Q+FT HG +M+ F A P V G NLVVPLQIGA DVAFP LN LSFW + G I + Sbjct: 80 NQLFTMHGTVMLLFYATPIVFGFANLVVPLQIGAPDVAFPRLNALSFWLFLFGASIALGG 139 Query: 159 SLGVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAP 218 L G A GW AY PLS +SPG G D WI+ L + G+GT L +N T++ MRAP Sbjct: 140 FLAPGGPADFGWTAYTPLSNAMHSPGAGGDLWIFGLIVGGLGTILGAVNMITTVVCMRAP 199 Query: 219 GMTMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINL 278 GM MF+MP+FTW L +V+++ +FP+LT + L DR LG H F GG M+ + +L Sbjct: 200 GMIMFRMPIFTWNILVTSVIVLVAFPLLTSALFGLAADRNLGAHVFDPANGGTML-WEHL 258 Query: 279 IWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHHFFTM 338 W +GHPEVYI+ LP FG+ +EI FSRK +FGYT+LV+AT+ I LS VW HH + Sbjct: 259 FWFFGHPEVYIIALPFFGIVTEIFPVFSRKPVFGYTTLVYATISIGALSIAVWAHHLY-- 316 Query: 339 GAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTG 398 GA + FF T +IA+PTG+K NW+ TM++G++ F + ML+++GF+VTF +GG+TG Sbjct: 317 ATGAVLLPFFSFMTFMIAVPTGIKFVNWIGTMWKGQLTFETPMLFSVGFLVTFLLGGLTG 376 Query: 399 VLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFW 458 V+LA P DF + +S F++AHFH V+ G +VF +AG+ +W+PK G L++ GK FW Sbjct: 377 VILASPPLDFHVTDSYFVVAHFHYVLFGTIVFATYAGVYFWFPKMTGRLLDDRLGKLHFW 436 Query: 459 FWIIGFFVAFMPLYALGFMGMTRRLSQQIDPQ-FHTMLMIAASGAVLIALGILCLVIQMY 517 +IGF F+ + LG GM RR + + F T+ +++ G+ ++ + +L V ++ Sbjct: 437 LTLIGFHTTFLVHHWLGAEGMPRRYADYLPTDGFTTLNIVSTIGSFILGVSMLPFVWNVF 496 Query: 518 VSIRDRDQNRDLTGDPWG-GRTLEWATSSPPPFYNFAVVPHVH-ERDAFW----EMKEKG 571 S R + DPWG G +LEWATS PPP +NF +P + ER AF M E+ Sbjct: 497 KSWRYGEPVT--VDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHMIERL 554 Query: 572 EAYKKPDHYE 581 A P + Sbjct: 555 RAESHPGRTQ 564 >6ADQ-F nrPDB Length = 575 Score = 409 bits (1052), Expect = e-114, Method: Compositional matrix adjust. Identities = 233/551 (42%), Positives = 336/551 (60%), Gaps = 18/551 (3%) Query: 49 LTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQIFTAHGV 108 +T+ DHK +GIMY +V L G A+ MR++ A+ FL ++Q+FT HG Sbjct: 32 ITTTDHKLIGIMYCVVCFAFFLVGGLMALFMRTELAMPGLQ---FLSNEQFNQLFTMHGT 88 Query: 109 IMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVS-LGVGEFAQ 167 +M+ F A P V G NLV+PLQIGA DVAFP LN LSFW + G ++ + G A Sbjct: 89 VMLLFYATPIVFGFANLVLPLQIGAPDVAFPRLNALSFWLFLFGALIAIAGFITPGGAAD 148 Query: 168 TGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGMTMFKMPV 227 GW AY PL+ +SPG G D WI L + G+GT L G+N T++ MRAPGMTMF+MP+ Sbjct: 149 FGWTAYSPLTDAIHSPGAGGDLWIMGLAVGGLGTILGGVNMITTVVCMRAPGMTMFRMPI 208 Query: 228 FTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAWGHPEV 287 FTW L ++L++ +FPILT + L DR+LG H + + G ++++ +L W +GHPEV Sbjct: 209 FTWNILVTSILVLIAFPILTAALFGLAADRHLGAHIY-DPANGGVLLWQHLFWFFGHPEV 267 Query: 288 YILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHHFFTMGAGANVNAF 347 YI+ LP FG+ SEI FSRK +FGYT+L++AT+ I LS VW HH + GA + F Sbjct: 268 YIIALPFFGIVSEIFPVFSRKPIFGYTTLIYATLAIAALSVAVWAHHMY--ATGAVLLPF 325 Query: 348 FGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTGVLLAVPGAD 407 F T +IA+PTG+K FNW+ TM++G++ F + ML+++GF++TF +GG++GVLLA P D Sbjct: 326 FSFMTFLIAVPTGIKFFNWIGTMWKGQLTFETPMLFSVGFLITFLLGGLSGVLLASPPLD 385 Query: 408 FVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFWFWIIGFFVA 467 F + +S F+IAHFH V+ G +VF +AG+ +W+PK G L+E GK FW IGF Sbjct: 386 FHVTDSYFVIAHFHYVLFGTIVFATYAGIYFWFPKMTGRLLDERLGKLHFWLTFIGFHTT 445 Query: 468 FMPLYALGFMGMTRRLSQQIDPQ-FHTMLMIAASGAVLIALGILCLVIQMYVSIRDRDQN 526 F+ + LG GM RR + + F T+ +I+ GA ++ + +L V ++ S R + Sbjct: 446 FLVQHWLGDEGMPRRYADYLPTDGFTTLNVISTVGAFILGVSMLPFVWNVFKSWRYGEPV 505 Query: 527 RDLTGDPWG-GRTLEWATSSPPPFYNFAVVPHVHERDAFWEM-------KEKGEAYKKPD 578 DPWG G +LEWATS PPP +NF +P + +E+ + + EA+ Sbjct: 506 T--VDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHMVERMRAEAHVGRA 563 Query: 579 HYEEIHMPKNS 589 H+ E+ S Sbjct: 564 HHPELETADKS 574 >2YEV-A nrPDB Length = 791 Score = 358 bits (920), Expect = 4e-99, Method: Compositional matrix adjust. Identities = 212/560 (37%), Positives = 327/560 (58%), Gaps = 23/560 (4%) Query: 39 GKWTYLWKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHH 98 G W LW + LT+VDHK++G+MY A ++++R+Q A+ + FL Sbjct: 10 GVWAVLW-DLLTTVDHKKIGLMYTATAFFAFALAGVFSLLIRTQLAVPNNQ---FLTGEQ 65 Query: 99 YDQIFTAHGVIMIFF-VAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVN 157 Y+QI T HG M+FF + + G N VVPL +GARDVA P +N S+W + ++L Sbjct: 66 YNQILTLHGATMLFFFIIQAGLTGFGNFVVPLMLGARDVALPRVNAFSYWAFLGAIVLAL 125 Query: 158 VS-LGVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMR 216 +S G GW Y P S S GVD+++ ++ L G + L NF TI +R Sbjct: 126 MSYFFPGGAPSVGWTFYYPFSAQSES---GVDFYLAAILLLGFSSLLGNANFVATIYNLR 182 Query: 217 APGMTMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYI 276 A GM+++KMP++ W+ A+VL + S LT L+ L+R +G +F +GG+ +++ Sbjct: 183 AQGMSLWKMPIYVWSVFAASVLNLFSLAGLTAATLLVLLERKIGLSWFNPAVGGDPVLFQ 242 Query: 277 NLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHHFF 336 W + HP VY+++LP G+ +E+A+TF+RK LFGY +VWA + I VL +VW HH F Sbjct: 243 QFFWFYSHPTVYVMLLPYLGILAEVASTFARKPLFGYRQMVWAQMGIVVLGTMVWAHHMF 302 Query: 337 TMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGM 396 T+G F T +IA+PTGVK+FN + T++ G++ + + W +GFI F +GG+ Sbjct: 303 TVGESTLFQIAFAFFTALIAVPTGVKLFNIIGTLWGGKLQMKTPLYWVLGFIFNFLLGGI 362 Query: 397 TGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRA 456 TGV+L++ D+ H+S F++AHFHNV++ G FG FAG+ YWWPK G +E G+ Sbjct: 363 TGVMLSMTPLDYQFHDSYFVVAHFHNVLMAGSGFGAFAGLYYWWPKMTGRMYDERLGRLH 422 Query: 457 FWFWIIGFFVAFMPLYALGFMGMTRR-LSQQID----PQFHTMLMIAASGAVLIALGILC 511 FW +++G+ + F+P YALG++GM RR + D P+ + +++ GA ++ LG L Sbjct: 423 FWLFLVGYLLTFLPQYALGYLGMPRRYYTYNADIAGWPELN---LLSTIGAYILGLGGLV 479 Query: 512 LVIQMYVSIRDRDQNRDLTGDPWGGRTLEWATSSPPPFYNFAV-VP-HVHERDAFWEMKE 569 + M+ S+R + D +PWGG TLEW T+SPP +NF V +P ++ K+ Sbjct: 480 WIYTMWKSLRSGPKAPD---NPWGGYTLEWLTASPPKAHNFDVKLPTEFPSERPLYDWKK 536 Query: 570 KGEAYKKPDHYEEIHMPKNS 589 KG KP+ IH+P +S Sbjct: 537 KGVEL-KPEDPAHIHLPNSS 555 >3ASN-A nrPDB Length = 514 Score = 343 bits (880), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 210/524 (40%), Positives = 301/524 (57%), Gaps = 21/524 (4%) Query: 46 KEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFL--PPHHYDQIF 103 WL S +HK +G +Y++ + G A ++++R A G+ G L Y+ + Sbjct: 4 NRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIR-----AELGQPGTLLGDDQIYNVVV 58 Query: 104 TAHGVIMIFFVAMPFVIG-LMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSLGV 162 TAH +MIFF+ MP +IG N +VPL IGA D+AFP +NN+SFW +L+ S V Sbjct: 59 TAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMV 118 Query: 163 GEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGMTM 222 A TGW YPPL+G G VD I+SL L+G+ + L INF TI+ M+ P M+ Sbjct: 119 EAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQ 178 Query: 223 FKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAW 282 ++ P+F W+ + VL++ S P+L + +L DR L T FF GG+ ++Y +L W + Sbjct: 179 YQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFF 238 Query: 283 GHPEVYILILPVFGVFSEIAATFS-RKRLFGYTSLVWATVCITVLSFIVWLHHFFTMGAG 341 GHPEVYILILP FG+ S I +S +K FGY +VWA + I L FIVW HH FT+G Sbjct: 239 GHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMD 298 Query: 342 ANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTGVLL 401 + A+F TMIIAIPTGVK+F+WL T++ G I + AM+W +GFI F+VGG+TG++L Sbjct: 299 VDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVL 358 Query: 402 AVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFWFWI 461 A D VLH++ +++AHFH V+ G VF G +W+P G+ LN+TW K F Sbjct: 359 ANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMF 418 Query: 462 IGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLIALGILCLVI----QMY 517 +G + F P + LG GM RR S P +TM +S I+L + L++ + + Sbjct: 419 VGVNMTFFPQHFLGLSGMPRRYSDY--PDAYTMWNTISSMGSFISLTAVMLMVFIIWEAF 476 Query: 518 VSIRDRDQNRDLTGDPWGGRTLEWATSSPPPFYNFAVVPHVHER 561 S R+ DLT LEW PPP++ F +V+ + Sbjct: 477 ASKREV-LTVDLT-----TTNLEWLNGCPPPYHTFEEPTYVNLK 514 >5Z62-A nrPDB Length = 513 Score = 342 bits (877), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 209/511 (40%), Positives = 297/511 (58%), Gaps = 13/511 (2%) Query: 46 KEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFL--PPHHYDQIF 103 WL S +HK +G +Y++ + G A ++++R A G+ G L H Y+ I Sbjct: 4 DRWLFSTNHKDIGTLYLLFGAWAGVLGTALSLLIR-----AELGQPGNLLGNDHIYNVIV 58 Query: 104 TAHGVIMIFFVAMPFVIG-LMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSLGV 162 TAH +MIFF+ MP +IG N +VPL IGA D+AFP +NN+SFW ++L+ S V Sbjct: 59 TAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSLLLLLASAMV 118 Query: 163 GEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGMTM 222 A TGW YPPL+G PG VD I+SL L+G+ + L INF TI+ M+ P MT Sbjct: 119 EAGAGTGWTVYPPLAGNYSHPGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQ 178 Query: 223 FKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAW 282 ++ P+F W+ L VL++ S P+L + +L DR L T FF GG+ ++Y +L W + Sbjct: 179 YQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFF 238 Query: 283 GHPEVYILILPVFGVFSEIAATFS-RKRLFGYTSLVWATVCITVLSFIVWLHHFFTMGAG 341 GHPEVYILILP FG+ S I +S +K FGY +VWA + I L FIVW HH FT+G Sbjct: 239 GHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMD 298 Query: 342 ANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTGVLL 401 + A+F TMIIAIPTGVK+F+WL T++ + + +A+LW +GFI F+VGG+TG++L Sbjct: 299 VDTRAYFTSATMIIAIPTGVKVFSWLATLHGSNMKWSAAVLWALGFIFLFTVGGLTGIVL 358 Query: 402 AVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFWFWI 461 A D VLH++ +++AHFH V+ G VF G +W+P G+ L++T+ K F Sbjct: 359 ANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFIHWFPLFSGYTLDQTYAKIHFTIMF 418 Query: 462 IGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLIALGILCLVIQMYVSIR 521 IG + F P + LG GM RR S P +T I +S I+L + L+I M Sbjct: 419 IGVNLTFFPQHFLGLSGMPRRYSDY--PDAYTTWNILSSVGSFISLTAVMLMIFMIWEAF 476 Query: 522 DRDQNRDLTGDPWGGRTLEWATSSPPPFYNF 552 + + +P LEW PPP++ F Sbjct: 477 ASKRKVLMVEEP--SMNLEWLYGCPPPYHTF 505 >3HB3-A nrPDB Length = 558 Score = 336 bits (861), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 206/540 (38%), Positives = 296/540 (54%), Gaps = 29/540 (5%) Query: 46 KEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQ--------------QALASAGEA 91 W S +HK +GI+Y+ A ++ L + MR + + +A A Sbjct: 20 TRWFMSTNHKDIGILYLFTAGIVGLISVCFTVYMRMELQHPGVQYMCLEGARLIADASAE 79 Query: 92 GFLPPHHYDQIFTAHGVIMIFFVAMPFVIG-LMNLVVPLQIGARDVAFPFLNNLSFWFTV 150 H ++ + T HGV+M+FFV +P + G N +PL IGA D+AFP LNNLS+W V Sbjct: 80 CTPNGHLWNVMITYHGVLMMFFVVIPALFGGFGNYFMPLHIGAPDMAFPRLNNLSYWMYV 139 Query: 151 VGVILVNVSL----GVGEFAQ-TGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTG 205 GV L SL G + GW+ YPPLS E G +D I+++ +SG + L Sbjct: 140 CGVALGVASLLAPGGNDQMGSGVGWVLYPPLSTTE--AGYSMDLAIFAVHVSGASSILGA 197 Query: 206 INFFVTILKMRAPGMTMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFT 265 IN T L MRAPGMT+FK+P+F W+ LI+ S P+L + +L +DR GT FF Sbjct: 198 INIITTFLNMRAPGMTLFKVPLFAWSVFITAWLILLSLPVLAGAITMLLMDRNFGTQFFD 257 Query: 266 NDMGGNMMMYINLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITV 325 GG+ ++Y +++W +GHPEVYI+ILP FG+ S + +TF++K +FGY +V A I + Sbjct: 258 PAGGGDPVLYQHILWFFGHPEVYIIILPGFGIISHVISTFAKKPIFGYLPMVLAMAAIGI 317 Query: 326 LSFIVWLHHFFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTI 385 L F+VW HH +T G A+F + TM IA+PTG+K+F+W+ TM+ G I F + MLW Sbjct: 318 LGFVVWAHHMYTAGMSLTQQAYFMLATMTIAVPTGIKVFSWIATMWGGSIEFKTPMLWAF 377 Query: 386 GFIVTFSVGGMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFG 445 GF+ F+VGG+TGV+L+ D V H++ +++AHFH V+ G VFG FAG+ YW K G Sbjct: 378 GFLFLFTVGGVTGVVLSQAPLDRVYHDTYYVVAHFHYVMSLGAVFGIFAGVYYWIGKMSG 437 Query: 446 FKLNETWGKRAFWFWIIGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLI 505 + E G+ FW IG + F P + LG GM RR +F I++ GA + Sbjct: 438 RQYPEWAGQLHFWMMFIGSNLIFFPQHFLGRQGMPRRYIDY-PVEFAYWNNISSIGAYIS 496 Query: 506 ALGILCLV-IQMYVSIRDRDQNRDLTGDPWG--GRTLEWATSSPPPFYNFAVVPHVHERD 562 L + I Y + N + W TLEW SPPP + F +P + D Sbjct: 497 FASFLFFIGIVFYTLFAGKRVN---VPNYWNEHADTLEWTLPSPPPEHTFETLPKREDWD 553 >3FYE-A nrPDB Length = 566 Score = 331 bits (848), Expect = 8e-91, Method: Compositional matrix adjust. Identities = 201/546 (36%), Positives = 298/546 (54%), Gaps = 37/546 (6%) Query: 47 EWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQ-----------QALASAGEAGFLP 95 W S +HK +G++Y+ ++ L A + MR + + L S GF Sbjct: 19 RWFMSTNHKDIGVLYLFTGGLVGLISVAFTVYMRMELMAPGVQFMCAEHLESGLVKGFFQ 78 Query: 96 P-------------HHYDQIFTAHGVIMIFFVAMPFVIG-LMNLVVPLQIGARDVAFPFL 141 H ++ + T HG++M+FFV +P + G N +PL IGA D+AFP + Sbjct: 79 SLWPSAVENCTPNGHLWNVMITGHGILMMFFVVIPALFGGFGNYFMPLHIGAPDMAFPRM 138 Query: 142 NNLSFWFTVVGVILVNVSL----GVGEFAQ-TGWLAYPPLSGIEYSPGVGVDYWIWSLQL 196 NNLS+W V G L SL G G+ GW+ YPPLS E G D I+++ L Sbjct: 139 NNLSYWLYVAGTSLAVASLFAPGGNGQLGSGIGWVLYPPLSTSE--SGYSTDLAIFAVHL 196 Query: 197 SGIGTTLTGINFFVTILKMRAPGMTMFKMPVFTWASLCANVLIIASFPILTVTVALLTLD 256 SG + L IN T L MRAPGMTM K+P+F W+ LI+ + P+L + +L D Sbjct: 197 SGASSILGAINMITTFLNMRAPGMTMHKVPLFAWSIFVTAWLILLALPVLAGAITMLLTD 256 Query: 257 RYLGTHFFTNDMGGNMMMYINLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSL 316 R GT FF GG+ ++Y +++W +GHPEVYI++LP FG+ S + ATF++K +FGY + Sbjct: 257 RNFGTTFFQPSGGGDPVLYQHILWFFGHPEVYIIVLPAFGIVSHVIATFAKKPIFGYLPM 316 Query: 317 VWATVCITVLSFIVWLHHFFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIV 376 V+A V I VL F+VW HH +T G ++F + TM+IA+PTG+KIF+W+ TM+ G I Sbjct: 317 VYAMVAIGVLGFVVWAHHMYTAGLSLTQQSYFMMATMVIAVPTGIKIFSWIATMWGGSIE 376 Query: 377 FHSAMLWTIGFIVTFSVGGMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGM 436 + MLW +GF+ F+VGG+TG++L+ D H++ +++AHFH V+ G VFG FAG+ Sbjct: 377 LKTPMLWALGFLFLFTVGGVTGIVLSQASVDRYYHDTYYVVAHFHYVMSLGAVFGIFAGI 436 Query: 437 TYWWPKAFGFKLNETWGKRAFWFWIIGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLM 496 +W K G + E GK FW +G + F P + LG GM RR + F T Sbjct: 437 YFWIGKMSGRQYPEWAGKLHFWMMFVGANLTFFPQHFLGRQGMPRRYIDYPE-AFATWNF 495 Query: 497 IAASGAVLIALGILCLVIQMYVSIRDRDQNRDLTGDPWG--GRTLEWATSSPPPFYNFAV 554 +++ GA L L + ++ ++ R + W TLEW +SPPP + F Sbjct: 496 VSSLGAFLSFASFLFFLGVIFYTL--TRGARVTANNYWNEHADTLEWTLTSPPPEHTFEQ 553 Query: 555 VPHVHE 560 +P + Sbjct: 554 LPKRED 559 >6HU9-a nrPDB Length = 534 Score = 330 bits (846), Expect = 1e-90, Method: Compositional matrix adjust. Identities = 191/487 (39%), Positives = 284/487 (58%), Gaps = 11/487 (2%) Query: 46 KEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQIFT- 104 + WL S + K + ++Y ++AI + G A ++++R + LA+ G H Q+F Sbjct: 3 QRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLE--LAAPGSQYL---HGNSQLFNV 57 Query: 105 ---AHGVIMIFFVAMPFVIG-LMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSL 160 H V+MIFF+ MP +IG N ++PL IGA D AFP +NN++FW +G++ + S Sbjct: 58 LVVGHAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTST 117 Query: 161 GVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGM 220 V A TGW YPPLS I+ G VD I++L L+ I + L INF VT L MR GM Sbjct: 118 LVESGAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGM 177 Query: 221 TMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIW 280 TM K+P+F W+ L++ S P+L+ + +L LDR T FF GG+ ++Y +L W Sbjct: 178 TMHKLPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFW 237 Query: 281 AWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHHFFTMGA 340 +GHPEVYILI+P FG+ S + +T+S+K +FG S+V+A I +L F+VW HH + +G Sbjct: 238 FFGHPEVYILIIPGFGIISHVVSTYSKKPVFGEISMVYAMASIGLLGFLVWSHHMYIVGL 297 Query: 341 GANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTGVL 400 A+ A+F TMIIAIPTG+KIF+WL T++ G I + ML+ I F+ F++GG+TGV Sbjct: 298 DADTRAYFTSATMIIAIPTGIKIFSWLATIHGGSIRLATPMLYAIAFLFLFTMGGLTGVA 357 Query: 401 LAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFWFW 460 LA D H++ +++ HFH V+ G +F FAG YW P+ G NE + FW Sbjct: 358 LANASLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLNYNEKLAQIQFWLI 417 Query: 461 IIGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLIALGILCLVIQMYVSI 520 IG V F P++ LG GM RR+ D F +A+ G+ + L + + +Y + Sbjct: 418 FIGANVIFFPMHFLGINGMPRRIPDYPD-AFAGWNYVASIGSFIATLSLFLFIYILYDQL 476 Query: 521 RDRDQNR 527 + N+ Sbjct: 477 VNGLNNK 483 >3EH4-A nrPDB Length = 618 Score = 55.1 bits (131), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 65/293 (22%), Positives = 118/293 (40%), Gaps = 33/293 (11%) Query: 269 GGNMMMYINLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSF 328 G + ++ L W GHP VY +LP + + I + RL A + +LS Sbjct: 274 GVDPLVARTLFWWTGHPIVYFWLLPAYAIIYTILPKQAGGRLVSDPMARLAFLLFLLLST 333 Query: 329 IVWLHH-FFTMGAGANVNAFFGITTMIIAIPT-------------------GVKIFNWLF 368 V HH F G + T+ +A+P+ G +F W+ Sbjct: 334 PVGFHHQFADPGIDPTWKMIHSVLTLFVAVPSLMTAFTVAASLEFAGRLRGGRGLFGWIR 393 Query: 369 TMYQGRIVFHSAMLWTIGFIVTFSVGGMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGGV 428 + F + +L +GFI GG G++ A D+V+HN+ ++ HFH + V Sbjct: 394 ALPWDNPAFVAPVLGLLGFI----PGGAGGIVNASFTLDYVVHNTAWVPGHFHLQVASLV 449 Query: 429 VFGCFAGMTYWWPKAFGFKLNETW---GKRAFWFWIIGFFVAFMPLYALGFMGMTRR--L 483 + + P G +++ G W W +G + + L+ G + + RR + Sbjct: 450 TLTAMGSLYWLLPNLTGKPISDAQRRLGLAVVWLWFLGMMIMAVGLHWAGLLNVPRRAYI 509 Query: 484 SQQIDPQFHT---MLMIAASGAVLIALGILCLVIQMYVSIRDRDQNRDLTGDP 533 +Q D H M+ +G VL+ + +L + ++ + R++ +L P Sbjct: 510 AQVPDAYPHAAVPMVFNVLAGIVLL-VALLLFIYGLFSVLLSRERKPELAEAP 561 >1BW0-A nrPDB Length = 416 Score = 30.8 bits (68), Expect = 2.2, Method: Compositional matrix adjust. Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 4/73 (5%) Query: 48 WLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPH---HYDQIFT 104 W S HK I+ V+L G + I+M + A+ AG+ +P HY+ + Sbjct: 88 WRNSFVHKEELKSTIVKDNVVLCSGGSHGILM-AITAICDAGDYALVPQPGFPHYETVCK 146 Query: 105 AHGVIMIFFVAMP 117 A+G+ M F+ P Sbjct: 147 AYGIGMHFYNCRP 159 >4NMY-A nrPDB Length = 303 Score = 30.4 bits (67), Expect = 2.9, Method: Compositional matrix adjust. Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 2/54 (3%) Query: 588 NSGAGIVIAAFSTIFGFAMIWHIWWLAIVGFAGMIITWI-VKSFDEDVDYYVPV 640 N+G AA T+ FA I+ W G + +I VK DE +DYY P+ Sbjct: 143 NTGQDDFFAAMKTV-DFAWIFEGWDAVKADLIGYDLNFIPVKDLDERLDYYTPL 195 >4IA5-A nrPDB Length = 591 Score = 28.5 bits (62), Expect = 8.8, Method: Compositional matrix adjust. Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 3/52 (5%) Query: 265 TNDMGGNMMMYINLIW---AWGHPEVYILILPVFGVFSEIAATFSRKRLFGY 313 TN G + ++ NL A+GHP+V+ LP F AT K+L Y Sbjct: 308 TNAKGDSWKLWENLAKQDPAFGHPDVFCENLPERSWFVSATATLENKKLAPY 359 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1FFT-A nrPDB 878 0.0 6HWH-V nrPDB 644 0.0 6ADQ-F nrPDB 640 0.0 3HB3-A nrPDB 638 0.0 3FYE-A nrPDB 618 e-177 5Z62-A nrPDB 591 e-169 3ASN-A nrPDB 589 e-168 6HU9-a nrPDB 576 e-165 2YEV-A nrPDB 567 e-162 3EH4-A nrPDB 241 7e-64 Sequences not found previously or not previously below threshold: 3MK7-A nrPDB 68 9e-12 4XYD-A nrPDB 48 1e-05 5GUW-B nrPDB 44 2e-04 3AYF-A nrPDB 33 0.58 4NMY-A nrPDB 32 0.92 2XZ4-A nrPDB 32 1.1 1T0H-B nrPDB 30 4.2 5W8S-A nrPDB 30 5.1 3U6N-A nrPDB 29 8.2 >1FFT-A nrPDB Length = 663 Score = 878 bits (2268), Expect = 0.0, Method: Composition-based stats. Identities = 663/663 (100%), Positives = 663/663 (100%) Query: 1 MFGKLSLDAVPFHEPIVMVTIAGIILGGLALVGLITYFGKWTYLWKEWLTSVDHKRLGIM 60 MFGKLSLDAVPFHEPIVMVTIAGIILGGLALVGLITYFGKWTYLWKEWLTSVDHKRLGIM Sbjct: 1 MFGKLSLDAVPFHEPIVMVTIAGIILGGLALVGLITYFGKWTYLWKEWLTSVDHKRLGIM 60 Query: 61 YIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQIFTAHGVIMIFFVAMPFVI 120 YIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQIFTAHGVIMIFFVAMPFVI Sbjct: 61 YIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQIFTAHGVIMIFFVAMPFVI 120 Query: 121 GLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSLGVGEFAQTGWLAYPPLSGIE 180 GLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSLGVGEFAQTGWLAYPPLSGIE Sbjct: 121 GLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSLGVGEFAQTGWLAYPPLSGIE 180 Query: 181 YSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGMTMFKMPVFTWASLCANVLII 240 YSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGMTMFKMPVFTWASLCANVLII Sbjct: 181 YSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGMTMFKMPVFTWASLCANVLII 240 Query: 241 ASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAWGHPEVYILILPVFGVFSE 300 ASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAWGHPEVYILILPVFGVFSE Sbjct: 241 ASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAWGHPEVYILILPVFGVFSE 300 Query: 301 IAATFSRKRLFGYTSLVWATVCITVLSFIVWLHHFFTMGAGANVNAFFGITTMIIAIPTG 360 IAATFSRKRLFGYTSLVWATVCITVLSFIVWLHHFFTMGAGANVNAFFGITTMIIAIPTG Sbjct: 301 IAATFSRKRLFGYTSLVWATVCITVLSFIVWLHHFFTMGAGANVNAFFGITTMIIAIPTG 360 Query: 361 VKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTGVLLAVPGADFVLHNSLFLIAHF 420 VKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTGVLLAVPGADFVLHNSLFLIAHF Sbjct: 361 VKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTGVLLAVPGADFVLHNSLFLIAHF 420 Query: 421 HNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFWFWIIGFFVAFMPLYALGFMGMT 480 HNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFWFWIIGFFVAFMPLYALGFMGMT Sbjct: 421 HNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFWFWIIGFFVAFMPLYALGFMGMT 480 Query: 481 RRLSQQIDPQFHTMLMIAASGAVLIALGILCLVIQMYVSIRDRDQNRDLTGDPWGGRTLE 540 RRLSQQIDPQFHTMLMIAASGAVLIALGILCLVIQMYVSIRDRDQNRDLTGDPWGGRTLE Sbjct: 481 RRLSQQIDPQFHTMLMIAASGAVLIALGILCLVIQMYVSIRDRDQNRDLTGDPWGGRTLE 540 Query: 541 WATSSPPPFYNFAVVPHVHERDAFWEMKEKGEAYKKPDHYEEIHMPKNSGAGIVIAAFST 600 WATSSPPPFYNFAVVPHVHERDAFWEMKEKGEAYKKPDHYEEIHMPKNSGAGIVIAAFST Sbjct: 541 WATSSPPPFYNFAVVPHVHERDAFWEMKEKGEAYKKPDHYEEIHMPKNSGAGIVIAAFST 600 Query: 601 IFGFAMIWHIWWLAIVGFAGMIITWIVKSFDEDVDYYVPVAEIEKLENQHFDEITKAGLK 660 IFGFAMIWHIWWLAIVGFAGMIITWIVKSFDEDVDYYVPVAEIEKLENQHFDEITKAGLK Sbjct: 601 IFGFAMIWHIWWLAIVGFAGMIITWIVKSFDEDVDYYVPVAEIEKLENQHFDEITKAGLK 660 Query: 661 NGN 663 NGN Sbjct: 661 NGN 663 >6HWH-V nrPDB Length = 583 Score = 644 bits (1662), Expect = 0.0, Method: Composition-based stats. Identities = 231/550 (42%), Positives = 333/550 (60%), Gaps = 17/550 (3%) Query: 40 KWTYLWKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHY 99 +WT L+K +T+ DHK +G+MY++ + G A+++R++ A+ FL Y Sbjct: 24 RWTLLYK-LVTTTDHKLIGMMYVVACFIFFFIGGLMALLLRTELAVPGLQ---FLSNEQY 79 Query: 100 DQIFTAHGVIMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVS 159 +Q+FT HG +M+ F A P V G NLVVPLQIGA DVAFP LN LSFW + G + Sbjct: 80 NQLFTMHGTVMLLFYATPIVFGFANLVVPLQIGAPDVAFPRLNALSFWLFLFGASIALGG 139 Query: 160 -LGVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAP 218 L G A GW AY PLS +SPG G D WI+ L + G+GT L +N T++ MRAP Sbjct: 140 FLAPGGPADFGWTAYTPLSNAMHSPGAGGDLWIFGLIVGGLGTILGAVNMITTVVCMRAP 199 Query: 219 GMTMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINL 278 GM MF+MP+FTW L +V+++ +FP+LT + L DR LG H F GG M ++ +L Sbjct: 200 GMIMFRMPIFTWNILVTSVIVLVAFPLLTSALFGLAADRNLGAHVFDPANGGTM-LWEHL 258 Query: 279 IWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHHFFTM 338 W +GHPEVYI+ LP FG+ +EI FSRK +FGYT+LV+AT+ I LS VW HH + Sbjct: 259 FWFFGHPEVYIIALPFFGIVTEIFPVFSRKPVFGYTTLVYATISIGALSIAVWAHHLY-- 316 Query: 339 GAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTG 398 GA + FF T +IA+PTG+K NW+ TM++G++ F + ML+++GF+VTF +GG+TG Sbjct: 317 ATGAVLLPFFSFMTFMIAVPTGIKFVNWIGTMWKGQLTFETPMLFSVGFLVTFLLGGLTG 376 Query: 399 VLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFW 458 V+LA P DF + +S F++AHFH V+ G +VF +AG+ +W+PK G L++ GK FW Sbjct: 377 VILASPPLDFHVTDSYFVVAHFHYVLFGTIVFATYAGVYFWFPKMTGRLLDDRLGKLHFW 436 Query: 459 FWIIGFFVAFMPLYALGFMGMTRRLSQQIDPQ-FHTMLMIAASGAVLIALGILCLVIQMY 517 +IGF F+ + LG GM RR + + F T+ +++ G+ ++ + +L V ++ Sbjct: 437 LTLIGFHTTFLVHHWLGAEGMPRRYADYLPTDGFTTLNIVSTIGSFILGVSMLPFVWNVF 496 Query: 518 VSIRDRDQNRDLTGDPWG-GRTLEWATSSPPPFYNFAVVPHVHERDAFW-----EMKEKG 571 S R + DPWG G +LEWATS PPP +NF +P + + M E+ Sbjct: 497 KSWRYGE--PVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHMIERL 554 Query: 572 EAYKKPDHYE 581 A P + Sbjct: 555 RAESHPGRTQ 564 >6ADQ-F nrPDB Length = 575 Score = 640 bits (1651), Expect = 0.0, Method: Composition-based stats. Identities = 235/556 (42%), Positives = 337/556 (60%), Gaps = 18/556 (3%) Query: 44 LWKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQIF 103 L + +T+ DHK +GIMY +V L G A+ MR++ A+ FL ++Q+F Sbjct: 27 LIYKLITTTDHKLIGIMYCVVCFAFFLVGGLMALFMRTELAMPGLQ---FLSNEQFNQLF 83 Query: 104 TAHGVIMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSL-GV 162 T HG +M+ F A P V G NLV+PLQIGA DVAFP LN LSFW + G ++ Sbjct: 84 TMHGTVMLLFYATPIVFGFANLVLPLQIGAPDVAFPRLNALSFWLFLFGALIAIAGFITP 143 Query: 163 GEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGMTM 222 G A GW AY PL+ +SPG G D WI L + G+GT L G+N T++ MRAPGMTM Sbjct: 144 GGAADFGWTAYSPLTDAIHSPGAGGDLWIMGLAVGGLGTILGGVNMITTVVCMRAPGMTM 203 Query: 223 FKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAW 282 F+MP+FTW L ++L++ +FPILT + L DR+LG H + GG ++++ +L W + Sbjct: 204 FRMPIFTWNILVTSILVLIAFPILTAALFGLAADRHLGAHIYDPANGG-VLLWQHLFWFF 262 Query: 283 GHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHHFFTMGAGA 342 GHPEVYI+ LP FG+ SEI FSRK +FGYT+L++AT+ I LS VW HH + GA Sbjct: 263 GHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLIYATLAIAALSVAVWAHHMY--ATGA 320 Query: 343 NVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTGVLLA 402 + FF T +IA+PTG+K FNW+ TM++G++ F + ML+++GF++TF +GG++GVLLA Sbjct: 321 VLLPFFSFMTFLIAVPTGIKFFNWIGTMWKGQLTFETPMLFSVGFLITFLLGGLSGVLLA 380 Query: 403 VPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFWFWII 462 P DF + +S F+IAHFH V+ G +VF +AG+ +W+PK G L+E GK FW I Sbjct: 381 SPPLDFHVTDSYFVIAHFHYVLFGTIVFATYAGIYFWFPKMTGRLLDERLGKLHFWLTFI 440 Query: 463 GFFVAFMPLYALGFMGMTRRLSQQIDPQ-FHTMLMIAASGAVLIALGILCLVIQMYVSIR 521 GF F+ + LG GM RR + + F T+ +I+ GA ++ + +L V ++ S R Sbjct: 441 GFHTTFLVQHWLGDEGMPRRYADYLPTDGFTTLNVISTVGAFILGVSMLPFVWNVFKSWR 500 Query: 522 DRDQNRDLTGDPWG-GRTLEWATSSPPPFYNFAVVPHVHERDAFWEM-------KEKGEA 573 + DPWG G +LEWATS PPP +NF +P + +E+ + + EA Sbjct: 501 YGE--PVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHMVERMRAEA 558 Query: 574 YKKPDHYEEIHMPKNS 589 + H+ E+ S Sbjct: 559 HVGRAHHPELETADKS 574 >3HB3-A nrPDB Length = 558 Score = 638 bits (1647), Expect = 0.0, Method: Composition-based stats. Identities = 202/541 (37%), Positives = 296/541 (54%), Gaps = 27/541 (4%) Query: 44 LWKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQ--------------ALASAG 89 + W S +HK +GI+Y+ A ++ L + MR + +A A Sbjct: 18 FFTRWFMSTNHKDIGILYLFTAGIVGLISVCFTVYMRMELQHPGVQYMCLEGARLIADAS 77 Query: 90 EAGFLPPHHYDQIFTAHGVIMIFFVAMPFVIG-LMNLVVPLQIGARDVAFPFLNNLSFWF 148 H ++ + T HGV+M+FFV +P + G N +PL IGA D+AFP LNNLS+W Sbjct: 78 AECTPNGHLWNVMITYHGVLMMFFVVIPALFGGFGNYFMPLHIGAPDMAFPRLNNLSYWM 137 Query: 149 TVVGVILVNVSLGVGEF-----AQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTL 203 V GV L SL + GW+ YPPLS E G +D I+++ +SG + L Sbjct: 138 YVCGVALGVASLLAPGGNDQMGSGVGWVLYPPLSTTE--AGYSMDLAIFAVHVSGASSIL 195 Query: 204 TGINFFVTILKMRAPGMTMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHF 263 IN T L MRAPGMT+FK+P+F W+ LI+ S P+L + +L +DR GT F Sbjct: 196 GAINIITTFLNMRAPGMTLFKVPLFAWSVFITAWLILLSLPVLAGAITMLLMDRNFGTQF 255 Query: 264 FTNDMGGNMMMYINLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCI 323 F GG+ ++Y +++W +GHPEVYI+ILP FG+ S + +TF++K +FGY +V A I Sbjct: 256 FDPAGGGDPVLYQHILWFFGHPEVYIIILPGFGIISHVISTFAKKPIFGYLPMVLAMAAI 315 Query: 324 TVLSFIVWLHHFFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLW 383 +L F+VW HH +T G A+F + TM IA+PTG+K+F+W+ TM+ G I F + MLW Sbjct: 316 GILGFVVWAHHMYTAGMSLTQQAYFMLATMTIAVPTGIKVFSWIATMWGGSIEFKTPMLW 375 Query: 384 TIGFIVTFSVGGMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKA 443 GF+ F+VGG+TGV+L+ D V H++ +++AHFH V+ G VFG FAG+ YW K Sbjct: 376 AFGFLFLFTVGGVTGVVLSQAPLDRVYHDTYYVVAHFHYVMSLGAVFGIFAGVYYWIGKM 435 Query: 444 FGFKLNETWGKRAFWFWIIGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAV 503 G + E G+ FW IG + F P + LG GM RR +F I++ GA Sbjct: 436 SGRQYPEWAGQLHFWMMFIGSNLIFFPQHFLGRQGMPRRYIDYP-VEFAYWNNISSIGAY 494 Query: 504 LIALGILCLVIQMYVSIRDRDQNRDLTGDPWG--GRTLEWATSSPPPFYNFAVVPHVHER 561 + L + ++ ++ + + W TLEW SPPP + F +P + Sbjct: 495 ISFASFLFFIGIVFYTLFAGKRVN--VPNYWNEHADTLEWTLPSPPPEHTFETLPKREDW 552 Query: 562 D 562 D Sbjct: 553 D 553 >3FYE-A nrPDB Length = 566 Score = 618 bits (1593), Expect = e-177, Method: Composition-based stats. Identities = 196/551 (35%), Positives = 294/551 (53%), Gaps = 37/551 (6%) Query: 44 LWKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAG-------------- 89 + W S +HK +G++Y+ ++ L A + MR + Sbjct: 16 FFTRWFMSTNHKDIGVLYLFTGGLVGLISVAFTVYMRMELMAPGVQFMCAEHLESGLVKG 75 Query: 90 ----------EAGFLPPHHYDQIFTAHGVIMIFFVAMPFVIG-LMNLVVPLQIGARDVAF 138 E H ++ + T HG++M+FFV +P + G N +PL IGA D+AF Sbjct: 76 FFQSLWPSAVENCTPNGHLWNVMITGHGILMMFFVVIPALFGGFGNYFMPLHIGAPDMAF 135 Query: 139 PFLNNLSFWFTVVGVILVNVSLGVGEF-----AQTGWLAYPPLSGIEYSPGVGVDYWIWS 193 P +NNLS+W V G L SL + GW+ YPPLS E G D I++ Sbjct: 136 PRMNNLSYWLYVAGTSLAVASLFAPGGNGQLGSGIGWVLYPPLSTSE--SGYSTDLAIFA 193 Query: 194 LQLSGIGTTLTGINFFVTILKMRAPGMTMFKMPVFTWASLCANVLIIASFPILTVTVALL 253 + LSG + L IN T L MRAPGMTM K+P+F W+ LI+ + P+L + +L Sbjct: 194 VHLSGASSILGAINMITTFLNMRAPGMTMHKVPLFAWSIFVTAWLILLALPVLAGAITML 253 Query: 254 TLDRYLGTHFFTNDMGGNMMMYINLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGY 313 DR GT FF GG+ ++Y +++W +GHPEVYI++LP FG+ S + ATF++K +FGY Sbjct: 254 LTDRNFGTTFFQPSGGGDPVLYQHILWFFGHPEVYIIVLPAFGIVSHVIATFAKKPIFGY 313 Query: 314 TSLVWATVCITVLSFIVWLHHFFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQG 373 +V+A V I VL F+VW HH +T G ++F + TM+IA+PTG+KIF+W+ TM+ G Sbjct: 314 LPMVYAMVAIGVLGFVVWAHHMYTAGLSLTQQSYFMMATMVIAVPTGIKIFSWIATMWGG 373 Query: 374 RIVFHSAMLWTIGFIVTFSVGGMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCF 433 I + MLW +GF+ F+VGG+TG++L+ D H++ +++AHFH V+ G VFG F Sbjct: 374 SIELKTPMLWALGFLFLFTVGGVTGIVLSQASVDRYYHDTYYVVAHFHYVMSLGAVFGIF 433 Query: 434 AGMTYWWPKAFGFKLNETWGKRAFWFWIIGFFVAFMPLYALGFMGMTRRLSQQIDPQFHT 493 AG+ +W K G + E GK FW +G + F P + LG GM RR + F T Sbjct: 434 AGIYFWIGKMSGRQYPEWAGKLHFWMMFVGANLTFFPQHFLGRQGMPRRYIDYPEA-FAT 492 Query: 494 MLMIAASGAVLIALGILCLVIQMYVSIRDRDQNRDLTGDPWG--GRTLEWATSSPPPFYN 551 +++ GA L L + ++ ++ R + W TLEW +SPPP + Sbjct: 493 WNFVSSLGAFLSFASFLFFLGVIFYTL--TRGARVTANNYWNEHADTLEWTLTSPPPEHT 550 Query: 552 FAVVPHVHERD 562 F +P + + Sbjct: 551 FEQLPKREDWE 561 >5Z62-A nrPDB Length = 513 Score = 591 bits (1523), Expect = e-169, Method: Composition-based stats. Identities = 203/517 (39%), Positives = 298/517 (57%), Gaps = 9/517 (1%) Query: 46 KEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQIFTA 105 WL S +HK +G +Y++ + G A ++++R++ H Y+ I TA Sbjct: 4 DRWLFSTNHKDIGTLYLLFGAWAGVLGTALSLLIRAELGQPGNLLG---NDHIYNVIVTA 60 Query: 106 HGVIMIFFVAMPFVIG-LMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSLGVGE 164 H +MIFF+ MP +IG N +VPL IGA D+AFP +NN+SFW ++L+ S V Sbjct: 61 HAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSLLLLLASAMVEA 120 Query: 165 FAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGMTMFK 224 A TGW YPPL+G PG VD I+SL L+G+ + L INF TI+ M+ P MT ++ Sbjct: 121 GAGTGWTVYPPLAGNYSHPGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQ 180 Query: 225 MPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAWGH 284 P+F W+ L VL++ S P+L + +L DR L T FF GG+ ++Y +L W +GH Sbjct: 181 TPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGH 240 Query: 285 PEVYILILPVFGVFSEIAATFS-RKRLFGYTSLVWATVCITVLSFIVWLHHFFTMGAGAN 343 PEVYILILP FG+ S I +S +K FGY +VWA + I L FIVW HH FT+G + Sbjct: 241 PEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVD 300 Query: 344 VNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTGVLLAV 403 A+F TMIIAIPTGVK+F+WL T++ + + +A+LW +GFI F+VGG+TG++LA Sbjct: 301 TRAYFTSATMIIAIPTGVKVFSWLATLHGSNMKWSAAVLWALGFIFLFTVGGLTGIVLAN 360 Query: 404 PGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFWFWIIG 463 D VLH++ +++AHFH V+ G VF G +W+P G+ L++T+ K F IG Sbjct: 361 SSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFIHWFPLFSGYTLDQTYAKIHFTIMFIG 420 Query: 464 FFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLIALGILCLVIQMYVSIRDR 523 + F P + LG GM RR S D T ++++ G+ + +L + L+I M Sbjct: 421 VNLTFFPQHFLGLSGMPRRYSDYPDAY-TTWNILSSVGSFI-SLTAVMLMIFMIWEAFAS 478 Query: 524 DQNRDLTGDPWGGRTLEWATSSPPPFYNFAVVPHVHE 560 + + +P LEW PPP++ F ++ Sbjct: 479 KRKVLMVEEP--SMNLEWLYGCPPPYHTFEEPVYMKS 513 >3ASN-A nrPDB Length = 514 Score = 589 bits (1519), Expect = e-168, Method: Composition-based stats. Identities = 201/518 (38%), Positives = 292/518 (56%), Gaps = 9/518 (1%) Query: 46 KEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQIFTA 105 WL S +HK +G +Y++ + G A ++++R++ Y+ + TA Sbjct: 4 NRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLG---DDQIYNVVVTA 60 Query: 106 HGVIMIFFVAMPFVIG-LMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSLGVGE 164 H +MIFF+ MP +IG N +VPL IGA D+AFP +NN+SFW +L+ S V Sbjct: 61 HAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEA 120 Query: 165 FAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGMTMFK 224 A TGW YPPL+G G VD I+SL L+G+ + L INF TI+ M+ P M+ ++ Sbjct: 121 GAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQ 180 Query: 225 MPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAWGH 284 P+F W+ + VL++ S P+L + +L DR L T FF GG+ ++Y +L W +GH Sbjct: 181 TPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGH 240 Query: 285 PEVYILILPVFGVFSEIAATFS-RKRLFGYTSLVWATVCITVLSFIVWLHHFFTMGAGAN 343 PEVYILILP FG+ S I +S +K FGY +VWA + I L FIVW HH FT+G + Sbjct: 241 PEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVD 300 Query: 344 VNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTGVLLAV 403 A+F TMIIAIPTGVK+F+WL T++ G I + AM+W +GFI F+VGG+TG++LA Sbjct: 301 TRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLAN 360 Query: 404 PGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFWFWIIG 463 D VLH++ +++AHFH V+ G VF G +W+P G+ LN+TW K F +G Sbjct: 361 SSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVG 420 Query: 464 FFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLIALGILCLVIQMYVSIRDR 523 + F P + LG GM RR S D +TM +S I+L + L++ + Sbjct: 421 VNMTFFPQHFLGLSGMPRRYSDYPDA--YTMWNTISSMGSFISLTAVMLMVFIIWEAFAS 478 Query: 524 DQNRDLTGDPWGGRTLEWATSSPPPFYNFAVVPHVHER 561 + LEW PPP++ F +V+ + Sbjct: 479 KREVLTVD--LTTTNLEWLNGCPPPYHTFEEPTYVNLK 514 >6HU9-a nrPDB Length = 534 Score = 576 bits (1486), Expect = e-165, Method: Composition-based stats. Identities = 192/530 (36%), Positives = 293/530 (55%), Gaps = 22/530 (4%) Query: 46 KEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQIFTA 105 + WL S + K + ++Y ++AI + G A ++++R + A + ++ + Sbjct: 3 QRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHG-NSQLFNVLVVG 61 Query: 106 HGVIMIFFVAMPFVIG-LMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSLGVGE 164 H V+MIFF+ MP +IG N ++PL IGA D AFP +NN++FW +G++ + S V Sbjct: 62 HAVLMIFFLVMPALIGGFGNYLLPLMIGATDTAFPRINNIAFWVLPMGLVCLVTSTLVES 121 Query: 165 FAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGMTMFK 224 A TGW YPPLS I+ G VD I++L L+ I + L INF VT L MR GMTM K Sbjct: 122 GAGTGWTVYPPLSSIQAHSGPSVDLAIFALHLTSISSLLGAINFIVTTLNMRTNGMTMHK 181 Query: 225 MPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAWGH 284 +P+F W+ L++ S P+L+ + +L LDR T FF GG+ ++Y +L W +GH Sbjct: 182 LPLFVWSIFITAFLLLLSLPVLSAGITMLLLDRNFNTSFFEVSGGGDPILYEHLFWFFGH 241 Query: 285 PEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHHFFTMGAGANV 344 PEVYILI+P FG+ S + +T+S+K +FG S+V+A I +L F+VW HH + +G A+ Sbjct: 242 PEVYILIIPGFGIISHVVSTYSKKPVFGEISMVYAMASIGLLGFLVWSHHMYIVGLDADT 301 Query: 345 NAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTGVLLAVP 404 A+F TMIIAIPTG+KIF+WL T++ G I + ML+ I F+ F++GG+TGV LA Sbjct: 302 RAYFTSATMIIAIPTGIKIFSWLATIHGGSIRLATPMLYAIAFLFLFTMGGLTGVALANA 361 Query: 405 GADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFWFWIIGF 464 D H++ +++ HFH V+ G +F FAG YW P+ G NE + FW IG Sbjct: 362 SLDVAFHDTYYVVGHFHYVLSMGAIFSLFAGYYYWSPQILGLNYNEKLAQIQFWLIFIGA 421 Query: 465 FVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLIALGILCLVIQMYVSIRDRD 524 V F P++ LG GM RR+ D F +A+ G+ + L + + +Y + + Sbjct: 422 NVIFFPMHFLGINGMPRRIPDYPDA-FAGWNYVASIGSFIATLSLFLFIYILYDQLVNGL 480 Query: 525 QN------------RDLTG-------DPWGGRTLEWATSSPPPFYNFAVV 555 N D + ++E+ +SPP ++F Sbjct: 481 NNKVNNKSVIYNKAPDFVESNTIFNLNTVKSSSIEFLLTSPPAVHSFNTP 530 >2YEV-A nrPDB Length = 791 Score = 567 bits (1461), Expect = e-162, Method: Composition-based stats. Identities = 216/602 (35%), Positives = 337/602 (55%), Gaps = 24/602 (3%) Query: 39 GKWTYLWKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHH 98 G W LW + LT+VDHK++G+MY A ++++R+Q A+ + FL Sbjct: 10 GVWAVLW-DLLTTVDHKKIGLMYTATAFFAFALAGVFSLLIRTQLAVPNNQ---FLTGEQ 65 Query: 99 YDQIFTAHGVIMIFF-VAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVN 157 Y+QI T HG M+FF + + G N VVPL +GARDVA P +N S+W + ++L Sbjct: 66 YNQILTLHGATMLFFFIIQAGLTGFGNFVVPLMLGARDVALPRVNAFSYWAFLGAIVLAL 125 Query: 158 VS-LGVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMR 216 +S G GW Y P S S GVD+++ ++ L G + L NF TI +R Sbjct: 126 MSYFFPGGAPSVGWTFYYPFSAQSES---GVDFYLAAILLLGFSSLLGNANFVATIYNLR 182 Query: 217 APGMTMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYI 276 A GM+++KMP++ W+ A+VL + S LT L+ L+R +G +F +GG+ +++ Sbjct: 183 AQGMSLWKMPIYVWSVFAASVLNLFSLAGLTAATLLVLLERKIGLSWFNPAVGGDPVLFQ 242 Query: 277 NLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHHFF 336 W + HP VY+++LP G+ +E+A+TF+RK LFGY +VWA + I VL +VW HH F Sbjct: 243 QFFWFYSHPTVYVMLLPYLGILAEVASTFARKPLFGYRQMVWAQMGIVVLGTMVWAHHMF 302 Query: 337 TMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGM 396 T+G F T +IA+PTGVK+FN + T++ G++ + + W +GFI F +GG+ Sbjct: 303 TVGESTLFQIAFAFFTALIAVPTGVKLFNIIGTLWGGKLQMKTPLYWVLGFIFNFLLGGI 362 Query: 397 TGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRA 456 TGV+L++ D+ H+S F++AHFHNV++ G FG FAG+ YWWPK G +E G+ Sbjct: 363 TGVMLSMTPLDYQFHDSYFVVAHFHNVLMAGSGFGAFAGLYYWWPKMTGRMYDERLGRLH 422 Query: 457 FWFWIIGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTM---LMIAASGAVLIALGILCLV 513 FW +++G+ + F+P YALG++GM RR + +++ GA ++ LG L + Sbjct: 423 FWLFLVGYLLTFLPQYALGYLGMPRRYYTY-NADIAGWPELNLLSTIGAYILGLGGLVWI 481 Query: 514 IQMYVSIRDRDQNRDLTGDPWGGRTLEWATSSPPPFYNFAV--VPHVHERDAFWEMKEKG 571 M+ S+R + D +PWGG TLEW T+SPP +NF V ++ K+KG Sbjct: 482 YTMWKSLRSGPKAPD---NPWGGYTLEWLTASPPKAHNFDVKLPTEFPSERPLYDWKKKG 538 Query: 572 EAYKKPDHYEEIHMPKNS-----GAGIVIAAFSTIFGFAMIWHIWWLAIVGFAGMIITWI 626 KP+ IH+P +S A + A F + + W+ + FA ++ W Sbjct: 539 VEL-KPEDPAHIHLPNSSFWPFYSAATLFAFFVAVAALPVPNVWMWVFLALFAYGLVRWA 597 Query: 627 VK 628 ++ Sbjct: 598 LE 599 >3EH4-A nrPDB Length = 618 Score = 241 bits (616), Expect = 7e-64, Method: Composition-based stats. Identities = 101/514 (19%), Positives = 190/514 (36%), Gaps = 61/514 (11%) Query: 55 KRLGIMYIIVAIVMLLRGFADAIMMRSQQALAS---AGEAGFLPPHHYDQIFTAHGVIMI 111 K+ + ++++ + L+ G + Y Q T HGV+ Sbjct: 74 KKATLYFLVLGFLALIVGSLFGPFQALNYGNVDAYPLLKRLLPFVQSYYQGLTLHGVLNA 133 Query: 112 FFVAMPFVIGLMNLVVPLQIGA-RDVAFPFLNNLSFWFTVVGVILVNVSLGVGEFAQTGW 170 F +M + ++ ++ L LS+W +G+++ + L E A + Sbjct: 134 IVFTQLFAQAIMVYLPARELNMRPNMG---LMWLSWWMAFIGLVVAALPLLANE-ATVLY 189 Query: 171 LAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKM--RAPGMTMFKM-PV 227 YPPL G W+ L L+ +L + R K+ P+ Sbjct: 190 TFYPPLKGH------------WAFYLGASVFVLSTWVSIYIVLDLWRRWKAANPGKVTPL 237 Query: 228 FTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAWGHPEV 287 T+ ++ ++ + L + L L G G + ++ L W GHP V Sbjct: 238 VTYMAVVFWLMWFLASLGLVLEAVLFLLPWSFGL-----VEGVDPLVARTLFWWTGHPIV 292 Query: 288 YILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHH-FFTMGAGANVNA 346 Y +LP + + I + RL A + +LS V HH F G Sbjct: 293 YFWLLPAYAIIYTILPKQAGGRLVSDPMARLAFLLFLLLSTPVGFHHQFADPGIDPTWKM 352 Query: 347 FFGITTMIIAIPT-------------------GVKIFNWLFTMYQGRIVFHSAMLWTIGF 387 + T+ +A+P+ G +F W+ + F + +L +GF Sbjct: 353 IHSVLTLFVAVPSLMTAFTVAASLEFAGRLRGGRGLFGWIRALPWDNPAFVAPVLGLLGF 412 Query: 388 IVTFSVGGMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFK 447 I GG G++ A D+V+HN+ ++ HFH + V + + P G Sbjct: 413 I----PGGAGGIVNASFTLDYVVHNTAWVPGHFHLQVASLVTLTAMGSLYWLLPNLTGKP 468 Query: 448 LNE---TWGKRAFWFWIIGFFVAFMPLYALGFMGMTRR--LSQQIDPQFHT---MLMIAA 499 +++ G W W +G + + L+ G + + RR ++Q D H M+ Sbjct: 469 ISDAQRRLGLAVVWLWFLGMMIMAVGLHWAGLLNVPRRAYIAQVPDAYPHAAVPMVFNVL 528 Query: 500 SGAVLIALGILCLVIQMYVSIRDRDQNRDLTGDP 533 +G VL+ + +L + ++ + R++ +L P Sbjct: 529 AGIVLL-VALLLFIYGLFSVLLSRERKPELAEAP 561 >3MK7-A nrPDB Length = 474 Score = 68.5 bits (166), Expect = 9e-12, Method: Composition-based stats. Identities = 37/263 (14%), Positives = 91/263 (34%), Gaps = 16/263 (6%) Query: 280 WAWGHPEVYILILPVF-GVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHHFFTM 338 W +GH V + F G+ + + ++ Y + + + HH Sbjct: 203 WWYGHNAVGFFLTAGFLGIMYYFVPKQAERPVYSYRLSIVHFWALITVYIWAGPHHLHYT 262 Query: 339 GAGANVNAFFGITTMIIAIPTGVKIFNWLFTMY--QGRIVFHSAMLWTIGFIVTFSVGGM 396 + + ++I+ P+ + N + T+ ++ + + + + + + Sbjct: 263 ALPDWAQSLGMVMSLILLAPSWGGMINGMMTLSGAWHKLRSDPILRFLVVSLAFYGMSTF 322 Query: 397 TGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKR- 455 G ++A+ + + H + + I H H +G V + + PK FG + + G Sbjct: 323 EGPMMAIKTVNALSHYTDWTIGHVHAGALGWVAMVSIGALYHLVPKVFGREQMHSIGLIN 382 Query: 456 -AFWFWIIGFFVAFMPLYALGFMG--MTRRLSQQIDPQF---------HTMLMIAASGAV 503 FW IG + ++ G M R ++ + H ++ G Sbjct: 383 THFWLATIGTVLYIASMWVNGIAQGLMWRAINDDGTLTYSFVESLEASHPGFVVRMIGGA 442 Query: 504 LIALGILCLVIQMYVSIRDRDQN 526 + G+L + + +++ Sbjct: 443 IFFAGMLVMAYNTWRTVQAAKPA 465 >4XYD-A nrPDB Length = 456 Score = 48.1 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 45/216 (20%), Positives = 78/216 (36%), Gaps = 17/216 (7%) Query: 313 YTSLVWATVCI-TVLSFIVWLHHFFTMGAGANVNAFFGITTMIIAIPT-GVKIFNWLFTM 370 + L+ AT +L HH+F +G I + + +P G+ F ++ + Sbjct: 227 WLYLIVATALFSGILGT---GHHYFWIGTPGYWQWIGSIFSALEVVPFFGMMAFAFV-MV 282 Query: 371 YQGRIVF--HSAMLWTIGFIVTFSVG-GMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGG 427 ++GR +A+LW++G G G+ G L + G ++ H + AH H G Sbjct: 283 WKGRKDHPNKAALLWSLGCATLAFFGAGVWGFLHTLHGINYYTHGTQITAAHGHLAFFGA 342 Query: 428 VVFGCFAGMTYWWPKAFGF-KLNETWGKRAFWFWIIGFFVAFMPLYALGFMGMTRR---- 482 V A +Y +P N+ +FW G L G + + Sbjct: 343 YVSLNLAIFSYAFPILRKRDPYNQVLNMASFWLMAGGMTFMTFVLTFAGTVQTHAQRVQG 402 Query: 483 --LSQQIDPQFHTMLMIAASGAVLIALGILCLVIQM 516 D M SG ++ LG L + + Sbjct: 403 DYFMDVQDAITIFYWMRFGSGIAVV-LGALLFIYAV 437 >5GUW-B nrPDB Length = 465 Score = 44.2 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 68/450 (15%), Positives = 153/450 (34%), Gaps = 50/450 (11%) Query: 61 YIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQIFTAHGVIMIFFVAMPFVI 120 Y + A+++ + ++M Q + ++ H ++I ++ F+ Sbjct: 19 YFVFALILFVGQILFGLIMGLQYVVGDFLFPAIP----FNVARMVHTNLLIVWLLFGFM- 73 Query: 121 GLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSLGVGEFAQTGWLAYPPLSGIE 180 G +VP + ++ P L + FW +L + + +A L+G E Sbjct: 74 GAAYYLVPEESDC-ELYSPKLAWILFWVFAAAGVLTILGYLLVPYAGLA-----RLTGNE 127 Query: 181 YSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGMTMFKMPVFTWASLCANVLII 240 P +G ++ + +S G + + F + GMT+ + + + LI Sbjct: 128 LWPTMGREF-LEQPTISKAGIVIVALGFLFNV------GMTVLRGRKTAISMVLMTGLIG 180 Query: 241 ASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAWGHPEVYILILPVFGVFSE 300 + L F+ + + W W V++ + V+ + Sbjct: 181 LALLFL--------------FSFYNPEN----LTRDKFYWWW---VVHLWVEGVWELIMG 219 Query: 301 IAATFSRKRLFGYTSLV-----WATVCITVLSFIVWL-HHFFTMGAGANVNAFFGITTMI 354 F ++ G V + + + ++S I+ HH+F +G + + + Sbjct: 220 AILAFVLVKITGVDREVIEKWLYVIIAMALISGIIGTGHHYFWIGVPGYWLWLGSVFSAL 279 Query: 355 IAIPTGVKIFNWLFTMYQGRIVF--HSAMLWTIGFIVTFSVG-GMTGVLLAVPGADFVLH 411 +P + T+ + R + + LW +G V +G G+ G + + ++ H Sbjct: 280 EPLPFFAMVLFAFNTINRRRRDYPNRAVALWAMGTTVMAFLGAGVWGFMHTLAPVNYYTH 339 Query: 412 NSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKA--FGFKLNETWGKRAFWFWIIGFFVAFM 469 + AH H G ++Y P+ G ++ W + + Sbjct: 340 GTQLTAAHGHMAFYGAYAMIVMTIISYAMPRLRGIGEAMDNRSQVLEMWGFWLMTVAMVF 399 Query: 470 PLYALGFMGMTRRLSQQIDPQFHTMLMIAA 499 L G+ + Q++ M +A Sbjct: 400 ITLFLSAAGVLQVWLQRMPADGAAMTFMAT 429 >3AYF-A nrPDB Length = 800 Score = 32.7 bits (73), Expect = 0.58, Method: Composition-based stats. Identities = 36/197 (18%), Positives = 68/197 (34%), Gaps = 11/197 (5%) Query: 275 YINLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHH 334 +I +W G EV+ +++ F + ++K +L + + I HH Sbjct: 505 WIIHLWVEGIFEVFAVVVIGFLLVQ--LRLVTKKSTV--RALYFQFTILLGSGVIGIGHH 560 Query: 335 FFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMY-----QGRIVFHSAMLWTIGFIV 389 ++ G+ A + + + IP + I + + + I + Sbjct: 561 YYYNGSPEVWIALGAVFSALEVIPLTLLILEAYEQYKMMRDGGANFPYKATFWFLISTAI 620 Query: 390 TFSVG-GMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFG-FK 447 VG G+ G L+ +P + H AH H ++G A + Y Sbjct: 621 WNLVGAGVFGFLINLPAVSYFEHGQFLTPAHGHAAMMGVYGMFAIAVLLYSLRNIVKPEA 680 Query: 448 LNETWGKRAFWFWIIGF 464 N+ W K + W IG Sbjct: 681 WNDKWLKFSCWMLNIGL 697 >4NMY-A nrPDB Length = 303 Score = 31.9 bits (71), Expect = 0.92, Method: Composition-based stats. Identities = 23/101 (22%), Positives = 35/101 (34%), Gaps = 9/101 (8%) Query: 547 PPFYNFAVVPHVHER------DAFWEMKEKGEAYKKPDHYEEIHMPKNSGAGIVIAAFST 600 P N + E K K + ++ + +G AA T Sbjct: 97 PKEKNITTAKDFEGKTYGGWGSPSEEAVFKAVMKKNRADFNKLKIVN-TGQDDFFAAMKT 155 Query: 601 IFGFAMIWHIWWLAIVGFAGMIITWI-VKSFDEDVDYYVPV 640 + FA I+ W G + +I VK DE +DYY P+ Sbjct: 156 V-DFAWIFEGWDAVKADLIGYDLNFIPVKDLDERLDYYTPL 195 >2XZ4-A nrPDB Length = 180 Score = 31.5 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 15/55 (27%), Positives = 21/55 (38%), Gaps = 2/55 (3%) Query: 167 QTGWL--AYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPG 219 GW+ Y L G + VG + I ++G G I F T + M P Sbjct: 65 SFGWVDIGYNFLVGGDGQIYVGRGWHIQGQHVNGYGAISVSIAFIGTFVNMEPPA 119 >1T0H-B nrPDB Length = 224 Score = 29.6 bits (65), Expect = 4.2, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 18/42 (42%), Gaps = 1/42 (2%) Query: 547 PPFYNFAV-VPHVHERDAFWEMKEKGEAYKKPDHYEEIHMPK 587 PP +F V + DA + + EAY K H ++P Sbjct: 177 PPQESFDVILDENQLEDACEHLADYLEAYWKATHPPSSNLPN 218 >5W8S-A nrPDB Length = 382 Score = 29.6 bits (65), Expect = 5.1, Method: Composition-based stats. Identities = 9/46 (19%), Positives = 18/46 (39%) Query: 375 IVFHSAMLWTIGFIVTFSVGGMTGVLLAVPGADFVLHNSLFLIAHF 420 I + S +W F +G T ++LA + ++ + F Sbjct: 118 IHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDKYNVPCRF 163 >3U6N-A nrPDB Length = 696 Score = 28.8 bits (63), Expect = 8.2, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 17/28 (60%) Query: 102 IFTAHGVIMIFFVAMPFVIGLMNLVVPL 129 + + H V+ IF ++GL NLV+PL Sbjct: 379 VLSGHVVVCIFGDVTSALVGLRNLVMPL 406 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.320 0.140 0.430 Lambda K H 0.267 0.0431 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,429,097 Number of Sequences: 36641 Number of extensions: 1293991 Number of successful extensions: 4064 Number of sequences better than 10.0: 48 Number of HSP's better than 10.0 without gapping: 30 Number of HSP's successfully gapped in prelim test: 45 Number of HSP's that attempted gapping in prelim test: 3893 Number of HSP's gapped (non-prelim): 100 length of query: 663 length of database: 10,336,785 effective HSP length: 103 effective length of query: 560 effective length of database: 6,562,762 effective search space: 3675146720 effective search space used: 3675146720 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.3 bits) S2: 63 (28.8 bits)