BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P0A9T0 (410 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2PA3-A nrPDB 823 0.0 3K5P-A nrPDB 466 e-131 1WWK-A nrPDB 201 5e-52 2G76-A nrPDB 177 9e-45 3DC2-A nrPDB 162 2e-40 2EKL-A nrPDB 154 9e-38 5AOV-A nrPDB 142 2e-34 5TX7-A nrPDB 137 9e-33 6BII-A nrPDB 137 1e-32 5OFW-B nrPDB 132 4e-31 2D0I-A nrPDB 126 2e-29 4ZGS-A nrPDB 125 3e-29 3KB6-A nrPDB 125 3e-29 3BA1-A nrPDB 124 7e-29 4DGS-A nrPDB 124 9e-29 4PRK-A nrPDB 117 9e-27 3FN4-A nrPDB 116 2e-26 2CUK-A nrPDB 115 4e-26 4G2N-A nrPDB 112 3e-25 1DXY-A nrPDB 112 4e-25 4XKJ-A nrPDB 111 6e-25 2DBZ-A nrPDB 110 1e-24 2OME-A nrPDB 109 2e-24 6ABJ-A nrPDB 109 2e-24 2YQ5-A nrPDB 108 3e-24 1HL3-A nrPDB 107 1e-23 4NFY-A nrPDB 106 2e-23 1GDH-A nrPDB 105 3e-23 3WR5-A nrPDB 103 1e-22 4LSW-A nrPDB 103 2e-22 2GO1-A nrPDB 102 3e-22 2DLD-A nrPDB 100 9e-22 3JTM-A nrPDB 100 1e-21 3WNV-A nrPDB 100 1e-21 4EBF-A nrPDB 100 2e-21 2WWR-A nrPDB 99 3e-21 5UOG-A nrPDB 99 4e-21 1J49-A nrPDB 97 1e-20 4XYG-A nrPDB 96 2e-20 5Z1Z-A nrPDB 96 3e-20 6IH4-A nrPDB 95 4e-20 3GG9-A nrPDB 94 8e-20 4CUK-A nrPDB 94 8e-20 4S1V-D nrPDB 94 2e-19 1XDW-A nrPDB 91 8e-19 6D4C-A nrPDB 89 3e-18 2W2L-A nrPDB 88 6e-18 5MH6-A nrPDB 86 3e-17 6ABI-A nrPDB 85 5e-17 5DT9-A nrPDB 84 1e-16 3OET-A nrPDB 78 6e-15 3HG7-A nrPDB 77 2e-14 2O4C-A nrPDB 76 3e-14 4HY3-A nrPDB 76 3e-14 4XA8-A nrPDB 75 7e-14 3EVT-A nrPDB 72 4e-13 5C5I-A nrPDB 67 1e-11 5TSD-A nrPDB 63 3e-10 3KBO-A nrPDB 62 6e-10 4N18-A nrPDB 55 5e-08 4WEQ-A nrPDB 52 5e-07 1QP8-A nrPDB 50 2e-06 3GVX-A nrPDB 43 2e-04 6CMZ-A nrPDB 37 0.022 5NFR-A nrPDB 33 0.16 6ES9-A nrPDB 32 0.37 1PZF-A nrPDB 32 0.39 2HJR-A nrPDB 32 0.41 3GKA-A nrPDB 31 1.0 5U8W-A nrPDB 31 1.1 5U1O-A nrPDB 30 2.1 3AK8-A nrPDB 30 2.2 4PLW-A nrPDB 30 2.2 2R9Z-A nrPDB 30 2.3 4DYU-A nrPDB 30 2.5 6JCV-A nrPDB 30 2.6 1Z9D-A nrPDB 30 2.6 1ONF-A nrPDB 30 2.8 3RI6-A nrPDB 29 3.6 1YB4-A nrPDB 29 3.6 5TR3-A nrPDB 29 4.0 4PLF-A nrPDB 28 5.2 6BZ0-A nrPDB 28 5.4 2FGC-A nrPDB 28 5.7 3UP5-A nrPDB 28 6.2 3SRE-A nrPDB 28 7.8 6FSZ-II nrPDB 28 8.4 >2PA3-A nrPDB Length = 410 Score = 823 bits (2127), Expect = 0.0, Method: Compositional matrix adjust. Identities = 405/410 (98%), Positives = 405/410 (98%) Query: 1 MAKVSLEKDKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLR 60 MAKVSLEKDKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLR Sbjct: 1 MAKVSLEKDKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLR 60 Query: 61 SRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGEL 120 SRTHLTEDVINAAEKLVAIG F IGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGEL Sbjct: 61 SRTHLTEDVINAAEKLVAIGAFAIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGEL 120 Query: 121 LLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFY 180 LLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFY Sbjct: 121 LLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFY 180 Query: 181 DIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASR 240 DIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASR Sbjct: 181 DIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASR 240 Query: 241 GTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEA 300 GTVVDIPAL DALASKHLAGAAIDVFPTEPATNSDPFTSPL EFDNVLLTPHIGGSTQEA Sbjct: 241 GTVVDIPALADALASKHLAGAAIDVFPTEPATNSDPFTSPLAEFDNVLLTPHIGGSTQEA 300 Query: 301 QENIGLEVAGKLIKYSDNGSTLSAVNFPEVSLPLHGGRRLMHIHENRPGVLTALNKIFAE 360 QENIGLEVAGKLIKYSDNGSTLSAVNFPEVSLPLH GRRLMHIHENRPGVLTALNKIFAE Sbjct: 301 QENIGLEVAGKLIKYSDNGSTLSAVNFPEVSLPLHVGRRLMHIHENRPGVLTALNKIFAE 360 Query: 361 QGVNIAAQYLQTSAQMGYVVIDIEADEDVAEKALQAMKAIPGTIRARLLY 410 QGVNIAAQYLQTSAQMGYVVIDIEADEDVAEKALQAMKAIPGTIRARLLY Sbjct: 361 QGVNIAAQYLQTSAQMGYVVIDIEADEDVAEKALQAMKAIPGTIRARLLY 410 >3K5P-A nrPDB Length = 416 Score = 466 bits (1198), Expect = e-131, Method: Compositional matrix adjust. Identities = 224/409 (54%), Positives = 297/409 (72%), Gaps = 1/409 (0%) Query: 3 KVSLEKDKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSR 62 ++SL +D+I LL+EG+ Q A+E +++GYTN+ ALD L ++I AH IG+RSR Sbjct: 8 RLSLSRDRINVLLLEGISQTAVEYFKSSGYTNVTHLPKALDKADLIKAISSAHIIGIRSR 67 Query: 63 THLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLL 122 T LTE++ AA +L+A+GCF +GTNQV+L AA KRGIPVFNAPFSNTRSVAELVIGE+++ Sbjct: 68 TQLTEEIFAAANRLIAVGCFSVGTNQVELKAARKRGIPVFNAPFSNTRSVAELVIGEIIM 127 Query: 123 LLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDI 182 L+R + + AH G W K A GS E RGK LGI+GYG+IG+Q+G LAESLGM V +YD Sbjct: 128 LMRRIFPRSVSAHAGGWEKTAIGSREVRGKTLGIVGYGNIGSQVGNLAESLGMTVRYYDT 187 Query: 183 ENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGT 242 +KL GN L +LL SDVVSLHVP + ST ++ ++ MK G+ LIN +RG+ Sbjct: 188 SDKLQYGNVKPAASLDELLKTSDVVSLHVPSSKSTSKLITEAKLRKMKKGAFLINNARGS 247 Query: 243 VVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQE 302 VD+ AL L HLAGAAIDVFP EPA+N + F++PL +NV+LTPHIGGST+EAQE Sbjct: 248 DVDLEALAKVLQEGHLAGAAIDVFPVEPASNGERFSTPLQGLENVILTPHIGGSTEEAQE 307 Query: 303 NIGLEVAGKLIKYSDNGSTLSAVNFPEVSLPLH-GGRRLMHIHENRPGVLTALNKIFAEQ 361 IG EV KL++YSD GST+ AVNFP+V LP G R MH+HENRPG+L +L +F+ Sbjct: 308 RIGTEVTRKLVEYSDVGSTVGAVNFPQVQLPPRPTGTRFMHVHENRPGILNSLMNVFSHH 367 Query: 362 GVNIAAQYLQTSAQMGYVVIDIEADEDVAEKALQAMKAIPGTIRARLLY 410 +NIA+Q+LQT ++GY+V++ + + ++ LQ ++ IPGTIRARLLY Sbjct: 368 HINIASQFLQTDGEVGYLVMEADGVGEASDAVLQEIREIPGTIRARLLY 416 >1WWK-A nrPDB Length = 307 Score = 201 bits (511), Expect = 5e-52, Method: Compositional matrix adjust. Identities = 128/312 (41%), Positives = 186/312 (59%), Gaps = 18/312 (5%) Query: 10 KIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDV 69 ++K L+ +H+KA++ L+ AG I ++ D+++L E ++D I +RS+ +T V Sbjct: 3 RMKVLVAAPLHEKAIQVLKDAGLEVI--YEEYPDEDRLVELVKDVEAIIVRSKPKVTRRV 60 Query: 70 INAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPE 129 I +A KL I +G + +D++AA ++GI V NAP +++RSVAEL +G + + R + Sbjct: 61 IESAPKLKVIARAGVGLDNIDVEAAKEKGIEVVNAPAASSRSVAELAVGLMFSVARKIAF 120 Query: 130 ANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLG 189 A+ K GVW K A E GK +GIIG+G IG Q+ +A +LGM + YD P Sbjct: 121 ADRKMREGVWAKKEAMGIELEGKTIGIIGFGRIGYQVAKIANALGMNILLYD-----PYP 175 Query: 190 NATQVQH-------LSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGT 242 N + + L LL SDVV++HVP ST +++ + + LMK ++LIN SRG Sbjct: 176 NEERAKEVNGKFVDLETLLKESDVVTIHVPLVESTYHLINEERLKLMKKTAILINTSRGP 235 Query: 243 VVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQE 302 VVD AL AL +AGA +DVF EP P PL +FDNV+LTPHIG ST EAQE Sbjct: 236 VVDTNALVKALKEGWIAGAGLDVFEEEPL----PKDHPLTKFDNVVLTPHIGASTVEAQE 291 Query: 303 NIGLEVAGKLIK 314 G+EVA K++K Sbjct: 292 RAGVEVAEKVVK 303 >2G76-A nrPDB Length = 335 Score = 177 bits (448), Expect = 9e-45, Method: Compositional matrix adjust. Identities = 111/316 (35%), Positives = 164/316 (51%), Gaps = 10/316 (3%) Query: 12 KFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVIN 71 K L+ + + + L+ G +E K L E+L ++D + +RS T +T DVIN Sbjct: 28 KVLISDSLDPCCRKILQDGGLQVVE--KQNLSKEELIAELQDCEGLIVRSATKVTADVIN 85 Query: 72 AAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEAN 131 AAEKL +G G + VDL+AA ++GI V N P N+ S AEL G ++ L R +P+A Sbjct: 86 AAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQAT 145 Query: 132 AKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYD--IENKLPLG 189 A G W + E GK LGI+G G IG ++ +S GM YD I ++ Sbjct: 146 ASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSAS 205 Query: 190 NATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPAL 249 Q L ++ + D +++H P PST ++ + K G ++N +RG +VD AL Sbjct: 206 FGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGAL 265 Query: 250 CDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVA 309 AL S AGAA+DVF EP P L + +NV+ PH+G ST+EAQ G E+A Sbjct: 266 LRALQSGQCAGAALDVFTEEP-----PRDRALVDHENVISCPHLGASTKEAQSRCGEEIA 320 Query: 310 GKLIKYSDNGSTLSAV 325 + + G +L+ V Sbjct: 321 VQFVDMV-KGKSLTGV 335 >3DC2-A nrPDB Length = 529 Score = 162 bits (411), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 97/269 (36%), Positives = 149/269 (55%), Gaps = 7/269 (2%) Query: 43 DDEQLKESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVF 102 D ++L ++ +A + +RS T + +V+ AA KL + +G + VD+DAA RG+ V Sbjct: 34 DRDKLLAAVPEADALLVRSATTVDAEVLAAAPKLKIVARAGVGLDNVDVDAATARGVLVV 93 Query: 103 NAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHI 162 NAP SN S AE + LL R +P A+A W + + E GK +G++G G I Sbjct: 94 NAPTSNIHSAAEHALALLLAASRQIPAADASLREHTWKRSSFSGTEIFGKTVGVVGLGRI 153 Query: 163 GTQLGILAESLGMYVYFYD--IENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNM 220 G + + G YV YD + ++ L DLL +D +S+H+P+ P T + Sbjct: 154 GQLVAQRIAAFGAYVVAYDPYVSPARAAQLGIELLSLDDLLARADFISVHLPKTPETAGL 213 Query: 221 MGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSP 280 + + ++ KPG +++NA+RG +VD AL DA+ H+ A +DVF TEP T+ SP Sbjct: 214 IDKEALAKTKPGVIIVNAARGGLVDEAALADAITGGHVRAAGLDVFATEPCTD-----SP 268 Query: 281 LCEFDNVLLTPHIGGSTQEAQENIGLEVA 309 L E V++TPH+G ST EAQ+ G +VA Sbjct: 269 LFELAQVVVTPHLGASTAEAQDRAGTDVA 297 Score = 29.6 bits (65), Expect = 2.3, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 29/63 (46%) Query: 337 GRRLMHIHENRPGVLTALNKIFAEQGVNIAAQYLQTSAQMGYVVIDIEADEDVAEKALQA 396 G L+ + +RPG L + + GVNI A L A+ I + D+DV + A Sbjct: 454 GINLIIHYVDRPGALGKIGTLLGTAGVNIQAAQLSEDAEGPGATILLRLDQDVPDDVRTA 513 Query: 397 MKA 399 + A Sbjct: 514 IAA 516 >2EKL-A nrPDB Length = 313 Score = 154 bits (388), Expect = 9e-38, Method: Compositional matrix adjust. Identities = 101/298 (33%), Positives = 160/298 (53%), Gaps = 10/298 (3%) Query: 11 IKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVI 70 +K L+ + + + +++LR G +++ + E+L I + I +RSRT +T+DVI Sbjct: 6 VKALITDPIDEILIKTLREKG-IQVDYMP-EISKEELLNIIGNYDIIVVRSRTKVTKDVI 63 Query: 71 NAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEA 130 +KL I IG + +D + A KR I V AP ++T S EL IG ++ R + + Sbjct: 64 EKGKKLKIIARAGIGLDNIDTEEAEKRNIKVVYAPGASTDSAVELTIGLMIAAARKMYTS 123 Query: 131 NAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFY---DIENKLP 187 A A G++ K+ E GK +GI+G+G IGT++GI+A ++GM V Y DI K Sbjct: 124 MALAKSGIFKKIEG--LELAGKTIGIVGFGRIGTKVGIIANAMGMKVLAYDILDIREKAE 181 Query: 188 LGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIP 247 NA V L +LL SDV+SLHV + K ++ + LMK +++N SR V+ Sbjct: 182 KINAKAVS-LEELLKNSDVISLHVTVSKDAKPIIDYPQFELMKDNVIIVNTSRAVAVNGK 240 Query: 248 ALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIG 305 AL D + + A DVF EP + + L + + V++T HIG T+EAQ+ + Sbjct: 241 ALLDYIKKGKVYAYATDVFWNEPP--KEEWELELLKHERVIVTTHIGAQTKEAQKRVA 296 >5AOV-A nrPDB Length = 336 Score = 142 bits (359), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 89/281 (31%), Positives = 138/281 (49%), Gaps = 14/281 (4%) Query: 45 EQLKESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNA 104 E+L E ++D + + ++V A +L + + +G + +D++ A +RGI V N Sbjct: 37 EKLLEKVKDVDALVTMLSERIDQEVFENAPRLRIVANYAVGYDNIDVEEATRRGIYVTNT 96 Query: 105 PFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAG-------SFEARGKKLGII 157 P T + A+ LL R V + + G W + +E GK +GI+ Sbjct: 97 PDVLTNATADHAFALLLATARHVVKGDKFVRSGEWKRKGIAWHPKWFLGYELYGKTIGIV 156 Query: 158 GYGHIGTQLGILAESLGMYVYFYDIENKLPLGN--ATQVQHLSDLLNMSDVVSLHVPENP 215 G+G IG + A+ M + +Y K + + L ++L SD V L VP Sbjct: 157 GFGRIGQAIARRAKGFNMRILYYSRTRKSQAEKELGAEYRPLEEVLKESDFVILAVPLTK 216 Query: 216 STKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSD 275 T M+ + + LMKP ++L+N +RG VVD AL AL +AGA +DVF EP N + Sbjct: 217 ETMYMINEERLKLMKPTAILVNIARGKVVDTKALIKALKEGWIAGAGLDVFEEEPYYNEE 276 Query: 276 PFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYS 316 F+ DNV+LTPHIG +T EA+E + VA LI + Sbjct: 277 LFS-----LDNVVLTPHIGSATFEAREAMAELVARNLIAFK 312 >5TX7-A nrPDB Length = 327 Score = 137 bits (345), Expect = 9e-33, Method: Compositional matrix adjust. Identities = 92/289 (31%), Positives = 147/289 (50%), Gaps = 13/289 (4%) Query: 45 EQLKESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNA 104 +++ E AH + L ++ L + A L + G ++VD+ AA GIPV N Sbjct: 37 DKIIERAAGAHVV-LTNKVPLDMSALQALPGLRFVSVLATGYDKVDVAAAGVLGIPVSNV 95 Query: 105 PFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSF------EARGKKLGIIG 158 P T SVA+ V LL L R + + G W + F E GK +GI+G Sbjct: 96 PGYGTDSVAQHVFALLLELCRRTALHDHRIRAGAWTQSPDWCFWDSTQEELTGKTMGIVG 155 Query: 159 YGHIGTQLGILAESLGMYVYFYDIENKL-PLGNATQVQHLSDLLNMSDVVSLHVPENPST 217 +G+ G ++G +A +LGM V Y ++ P + L +L +DVVSLH P P T Sbjct: 156 FGNTGRRVGRIANALGMNVIAYAPRSRFDPDYRPFEHVGLDELFTSADVVSLHCPLTPET 215 Query: 218 KNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPF 277 + ++ A+ ++ M+PGS LIN +RG ++D A+ +AL S LAGA +DV EP +P Sbjct: 216 EGLVDARRLASMRPGSYLINTARGPLLDERAVAEALDSGRLAGAGLDVLSQEPPAADNPL 275 Query: 278 TSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDNGSTLSAVN 326 S N L+TPH+ +++ A+ + A + + + G+ ++ VN Sbjct: 276 LS----AKNCLITPHLAWASRTARRTLMDSTAANIRSFIE-GTPVNVVN 319 >6BII-A nrPDB Length = 333 Score = 137 bits (344), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 99/327 (30%), Positives = 157/327 (48%), Gaps = 16/327 (4%) Query: 10 KIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDV 69 K K L+ + + +E LR + H+ + E L E ++D + + +V Sbjct: 2 KPKVLITRAIPENGIELLREHFEVEVWEHEHEIPREVLLEKVKDVDALVTMLSEKIDREV 61 Query: 70 INAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPE 129 +AA +L + + +G + +D++ A KRGI V N P T + A+L LL R V + Sbjct: 62 FDAAPRLRIVANYAVGYDNIDIEEATKRGIYVTNTPDVLTDATADLAWALLLAAARHVVK 121 Query: 130 ANAKAHRGVWNKLAAG-------SFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDI 182 + G W + ++ GK +GI+G+G IG + A+ GM + Y Sbjct: 122 GDKFVRSGEWKRRGIAWHPKMFLGYDVYGKTIGIVGFGRIGQAIAKRAKGFGMRI-LYTA 180 Query: 183 ENKLPLGN---ATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINAS 239 ++ P + + L +LL SD V L VP T +M+ + + LMKP ++L+N + Sbjct: 181 RSRKPEAEKELGAEFKPLEELLRESDFVVLAVPLTKETYHMINEERLRLMKPTAVLVNVA 240 Query: 240 RGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQE 299 RG VVD AL AL +A A +DVF EP + + F DNV+LTPHIG +T Sbjct: 241 RGKVVDTKALIRALKEGWIAAAGLDVFEEEPYYDEELFA-----LDNVVLTPHIGSATFG 295 Query: 300 AQENIGLEVAGKLIKYSDNGSTLSAVN 326 A+E + VA LI + + + VN Sbjct: 296 AREGMAELVAKNLIAFKNGEVPPTLVN 322 >5OFW-B nrPDB Length = 223 Score = 132 bits (331), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 80/229 (34%), Positives = 117/229 (51%), Gaps = 12/229 (5%) Query: 101 VFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYG 160 V N P N+ S AEL G ++ L R +P+A A G W + E GK LGI+G G Sbjct: 3 VMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLG 62 Query: 161 HIGTQLGILAESLGMYVYFYD--IENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTK 218 IG ++ +S GM YD I ++ Q L ++ + D +++H P PST Sbjct: 63 RIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTT 122 Query: 219 NMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFT 278 ++ + K G ++N +RG +VD AL AL S AGAA+DVF EP P Sbjct: 123 GLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEP-----PRD 177 Query: 279 SPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSD--NGSTLSAV 325 L + +NV+ PH+G ST+EAQ G E+A +++ D G +L+ V Sbjct: 178 RALVDHENVISCPHLGASTKEAQSRCGEEIA---VQFVDMVKGKSLTGV 223 >2D0I-A nrPDB Length = 333 Score = 126 bits (317), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 92/304 (30%), Positives = 150/304 (49%), Gaps = 16/304 (5%) Query: 19 VHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVINAAEKLVA 78 + ++ALE L+ I + E+LK I I + T +T +V+ AE+L Sbjct: 11 MKREALEELKKYADVEIILYPSG---EELKGVIGRFDGIIVSPTTKITREVLENAERLKV 67 Query: 79 IGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGV 138 I C G + +DL+ A KRGI V + +VAE +G ++ L+R + A+ RG Sbjct: 68 ISCHSAGYDNIDLEEATKRGIYVTKVSGLLSEAVAEFTVGLIINLMRKIHYADKFIRRGE 127 Query: 139 WN---KLAAG--SFEA-RGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNAT 192 W K+ G E+ GKK+GI+G G IG + G+ +Y++ K+ + Sbjct: 128 WESHAKIWTGFKRIESLYGKKVGILGMGAIGKAIARRLIPFGVKLYYWSRHRKVNVEKEL 187 Query: 193 QVQHL--SDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALC 250 + +++ +LL SD+V L +P T +++ + + ++ G L+N RG +VD A+ Sbjct: 188 KARYMDIDELLEKSDIVILALPLTRDTYHIINEERVKKLE-GKYLVNIGRGALVDEKAVT 246 Query: 251 DALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAG 310 +A+ L G A DVF EP + F E++ V LTPH G EAQE++G Sbjct: 247 EAIKQGKLKGYATDVFEKEPVREHELFK---YEWETV-LTPHYAGLALEAQEDVGFRAVE 302 Query: 311 KLIK 314 L+K Sbjct: 303 NLLK 306 >4ZGS-A nrPDB Length = 386 Score = 125 bits (315), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 87/266 (32%), Positives = 134/266 (50%), Gaps = 20/266 (7%) Query: 56 FIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAEL 115 F+ R+ + +++ A KL+A+ C G ++VDL A A+ G+ V P + SVAE Sbjct: 85 FVNDRADASVIKELAKAGVKLIALRC--AGFDRVDLHACAEHGVRVVRVPTYSPESVAEH 142 Query: 116 VIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGM 175 + + L R + +A + G ++ E R K +G++G G IG Q + + +G Sbjct: 143 AVALIFALNRHLTDAYIRVRMGNYSLSGLVGVEMRHKVVGVVGTGAIGQQAARILKGIGC 202 Query: 176 YVYFYDIENKLPLGNATQVQHLS--DLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGS 233 V+ YDI+ P A + ++S +LL MSD+V+LH P PST+ ++ + I MK G Sbjct: 203 KVFAYDIKPN-PAVEAMGIPYVSLDELLAMSDIVTLHCPLLPSTRQLINKESIQKMKKGV 261 Query: 234 LLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPA------TNSDPFT--------- 278 +LIN SRG ++D AL DAL S + +DV+ E T DP Sbjct: 262 MLINVSRGGLIDSAALFDALESGQIGALGLDVYENEGGLFFVDHTKFDPSVRMQKWDRQF 321 Query: 279 SPLCEFDNVLLTPHIGGSTQEAQENI 304 L + VL+TPH T+EA NI Sbjct: 322 RTLLSYPQVLVTPHTAFLTEEALNNI 347 >3KB6-A nrPDB Length = 334 Score = 125 bits (314), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 94/305 (30%), Positives = 147/305 (48%), Gaps = 25/305 (8%) Query: 34 NIEFHKGALDDEQLK-----------ESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCF 82 ++ F++ AL D LK ++ A I + LTE++++ +L I Sbjct: 12 DVPFYQEALKDLSLKIYTTDVSKVPENELKKAELISVFVYDKLTEELLSKMPRLKLIHTR 71 Query: 83 CIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKL 142 +G + +DLD K+GI V + P + SVAE +L L++ + + + +++ Sbjct: 72 SVGFDHIDLDYCKKKGILVTHIPAYSPESVAEHTFAMILTLVKRLKRIEDRVKKLNFSQD 131 Query: 143 AAG-SFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQV-QHLSDL 200 + + E LG+IG G IG+++ + + GM V YD+ + L V L +L Sbjct: 132 SEILARELNRLTLGVIGTGRIGSRVAMYGLAFGMKVLCYDVVKREDLKEKGCVYTSLDEL 191 Query: 201 LNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAG 260 L SDV+SLHVP T +M+ + ISLMK G LIN +RG VVD AL A +G Sbjct: 192 LKESDVISLHVPYTKETHHMINEERISLMKDGVYLINTARGKVVDTDALYRAYQRGKFSG 251 Query: 261 AAIDVFPTE-----------PATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVA 309 +DVF E AT+ + L DNV++TPHI T ++ E I E Sbjct: 252 LGLDVFEDEEILILKKYTEGKATDKNLKILELACKDNVIITPHIAYYTDKSLERIREETV 311 Query: 310 GKLIK 314 K++K Sbjct: 312 -KVVK 315 >3BA1-A nrPDB Length = 333 Score = 124 bits (311), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 82/249 (32%), Positives = 125/249 (50%), Gaps = 13/249 (5%) Query: 68 DVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGV 127 ++I+A KL + F +G ++VDL ++G+ V N P T VA+L IG +L +LR + Sbjct: 80 ELIDALPKLEIVSSFSVGLDKVDLIKCEEKGVRVTNTPDVLTDDVADLAIGLILAVLRRI 139 Query: 128 PEANAKAHRGVWNKLAAGSFEA----RGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIE 183 E + RG W G F+ GK++GIIG G IG + AE+ + ++ Sbjct: 140 CECDKYVRRGAWK---FGDFKLTTKFSGKRVGIIGLGRIGLAVAERAEAFDCPISYFS-R 195 Query: 184 NKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTV 243 +K P N T + +L + SD++ + P P T +++ + I + P +LIN RG Sbjct: 196 SKKPNTNYTYYGSVVELASNSDILVVACPLTPETTHIINREVIDALGPKGVLINIGRGPH 255 Query: 244 VDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQEN 303 VD P L AL L GA +DVF EP F +NV+L PH+G T E ++ Sbjct: 256 VDEPELVSALVEGRLGGAGLDVFEREPEVPEKLFG-----LENVVLLPHVGSGTVETRKV 310 Query: 304 IGLEVAGKL 312 + V G L Sbjct: 311 MADLVVGNL 319 >4DGS-A nrPDB Length = 340 Score = 124 bits (310), Expect = 9e-29, Method: Compositional matrix adjust. Identities = 86/242 (35%), Positives = 129/242 (53%), Gaps = 21/242 (8%) Query: 74 EKLVAIGCFCI---GTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEA 130 EKL ++G I GT++VDL A +R I V P VA+L I +L +LR V + Sbjct: 89 EKLPSLGIIAINGVGTDKVDLARARRRNIDVTTTPGVLADDVADLGIALMLAVLRRVGDG 148 Query: 131 NAKAHRGVWNKLAAG-----SFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENK 185 + G W AAG +GK++G++G G IG L AE+ GM V ++ N+ Sbjct: 149 DRLVREGRW---AAGEQLPLGHSPKGKRIGVLGLGQIGRALASRAEAFGMSVRYW---NR 202 Query: 186 LPLGNATQVQHLS--DLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTV 243 L + H S DL SDV+++ V + +T+N++ A + + P +++N +RG V Sbjct: 203 STLSGVDWIAHQSPVDLARDSDVLAVCVAASAATQNIVDASLLQALGPEGIVVNVARGNV 262 Query: 244 VDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQEN 303 VD AL +AL S +AGA +DVF EPA S+ T+P N +L PH G +T E + Sbjct: 263 VDEDALIEALKSGTIAGAGLDVFVNEPAIRSEFHTTP-----NTVLMPHQGSATVETRMA 317 Query: 304 IG 305 +G Sbjct: 318 MG 319 >4PRK-A nrPDB Length = 336 Score = 117 bits (293), Expect = 9e-27, Method: Compositional matrix adjust. Identities = 75/236 (31%), Positives = 120/236 (50%), Gaps = 9/236 (3%) Query: 78 AIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRG 137 +IG +GTN +D D A K + V N P + R++AE+ + + + L R + E A +G Sbjct: 72 SIGLRIVGTNTIDFDLAKKYHLTVTNVPVYSPRAIAEMAVTQAMYLNRKIGEFKANMDKG 131 Query: 138 VW-NKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQH 196 + N + S E K +G+IG GHIG+ + + ++G V YD+ + Sbjct: 132 DFTNPDSLISNEIYNKTIGLIGVGHIGSAVAQIFSAMGAKVLAYDVIYNPEVEPYLTYAD 191 Query: 197 LSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASK 256 +L +D++SLH P ST+NM+G K+ + MK ++LINA+RG +VD AL +AL Sbjct: 192 FDTVLKEADIISLHTPLLKSTENMIGKKQFAEMKNDAILINAARGELVDTAALIEALEKH 251 Query: 257 HLAGAAIDVFPTEPA---TNSDPFTSP-----LCEFDNVLLTPHIGGSTQEAQENI 304 +A A +D E + D P L NV++TPH T+ + N+ Sbjct: 252 EIAAAGLDTLAHESSYFFKKVDDAQIPADYKKLAAMPNVIVTPHSAYFTKTSVRNM 307 >3FN4-A nrPDB Length = 401 Score = 116 bits (291), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 85/267 (31%), Positives = 135/267 (50%), Gaps = 14/267 (5%) Query: 44 DEQLKESIRDAHFIGLRS--RTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPV 101 D +L++ + DA I + +LT + I A KL IG++ VDL AA I V Sbjct: 80 DSELEKHLHDAEVIISQPFWPAYLTAERIAKAPKLKLALTAGIGSDHVDLQAAIDNNITV 139 Query: 102 FNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWN--KLAAGSFEARGKKLGIIGY 159 + N+ SVAE V+ +L L+R ++ A G WN A S++ G +G + Sbjct: 140 AEVTYCNSNSVAEHVVMMVLGLVRNYIPSHDWARNGGWNIADCVARSYDVEGMHVGTVAA 199 Query: 160 GHIGTQLGILAESLGMYVYFYDIENKLPLG-----NATQVQHLSDLLNMSDVVSLHVPEN 214 G IG ++ L M++++ D ++LP N T D+ DVV+L+ P + Sbjct: 200 GRIGLRVLRLLAPFDMHLHYTD-RHRLPEAVEKELNLTWHATREDMYGACDVVTLNCPLH 258 Query: 215 PSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNS 274 P T++M+ + + L K G+ L+N +RG + D A+ AL S LAG A DV+ +PA N Sbjct: 259 PETEHMINDETLKLFKRGAYLVNTARGKLCDRDAIVRALESGRLAGYAGDVWFPQPAPND 318 Query: 275 DPFTSPLCEFDNVLLTPHIGGSTQEAQ 301 P+ + + +TPHI G++ AQ Sbjct: 319 HPWRT----MPHNGMTPHISGTSLSAQ 341 >2CUK-A nrPDB Length = 311 Score = 115 bits (288), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 99/303 (32%), Positives = 154/303 (50%), Gaps = 14/303 (4%) Query: 11 IKFLLVEGVHQKALESLRAAGYTNIEFHKGA-LDDEQLKESIRDAHFIGLRSRTHLTEDV 69 ++ L+ + KAL+ LR G +E H+G L +L + + A + + +V Sbjct: 1 MRVLVTRTLPGKALDRLRERGL-EVEVHRGLFLPKAELLKRVEGAVGLIPTVEDRIDAEV 59 Query: 70 INAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPE 129 ++ A+ L I C+ +G + VDL+AA +RGI V + P T + A+L + LL + R V E Sbjct: 60 MDRAKGLKVIACYSVGVDHVDLEAARERGIRVTHTPGVLTEATADLTLALLLAVARRVVE 119 Query: 130 ANAKAHRGVWNKL---AAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKL 186 A A G+W + +G LG++G G IG + A + GM V ++ + Sbjct: 120 GAAYARDGLWKAWHPELLLGLDLQGLTLGLVGMGRIGQAVAKRALAFGMRVVYH---ART 176 Query: 187 PLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDI 246 P L +LL +DVVSLH P P T ++ + + MK G++L+N +RG +VD Sbjct: 177 PKPLPYPFLSLEELLKEADVVSLHTPLTPETHRLLNRERLFAMKRGAILLNTARGALVDT 236 Query: 247 PALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGL 306 AL +AL HL GA +DV EP P PL N ++TPHIG + + +E + Sbjct: 237 EALVEALRG-HLFGAGLDVTDPEPL----PPGHPLYALPNAVITPHIGSAGRTTRERMA- 290 Query: 307 EVA 309 EVA Sbjct: 291 EVA 293 >4G2N-A nrPDB Length = 345 Score = 112 bits (279), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 79/250 (31%), Positives = 123/250 (49%), Gaps = 17/250 (6%) Query: 65 LTEDVINAAEK-LVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLL 123 +T +VI + L I +G + +D+ AA GI V + P + + AE+ + +L Sbjct: 83 ITAEVIRKLQPGLKTIATLSVGYDHIDMAAARSLGIKVLHTPDVLSDACAEIAMLLVLNA 142 Query: 124 LRGVPEANAKAHRGVWNKLAAGSFEA---RGKKLGIIGYGHIGTQLGILAESLGMYVYFY 180 R EA+ G W G++LGI G G IG + A G+ ++++ Sbjct: 143 CRRGYEADRMVRSGSWPGWGPTQLLGMGLTGRRLGIFGMGRIGRAIATRARGFGLAIHYH 202 Query: 181 DIENKLPLGNATQ---VQH--LSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLL 235 N+ L +A + + H L LL SD+ + P P K + I+ + G+++ Sbjct: 203 ---NRTRLSHALEEGAIYHDTLDSLLGASDIFLIAAPGRPELKGFLDHDRIAKIPEGAVV 259 Query: 236 INASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGG 295 IN SRG +++ AL +AL SKHL A +DVF EPA DP L DN+ LTPHIG Sbjct: 260 INISRGDLINDDALIEALRSKHLFAAGLDVFANEPAI--DPRYRSL---DNIFLTPHIGS 314 Query: 296 STQEAQENIG 305 +T E ++ +G Sbjct: 315 ATHETRDAMG 324 >1DXY-A nrPDB Length = 333 Score = 112 bits (279), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 91/314 (28%), Positives = 145/314 (46%), Gaps = 29/314 (9%) Query: 35 IEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFC-----IGTNQV 89 +E+H LD+ ++ + F G+ S T EK+ A G +GT+ + Sbjct: 27 LEYHTEFLDENTVEWA---KGFDGINS-LQTTPYAAGVFEKMHAYGIKFLTIRNVGTDNI 82 Query: 90 DLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSF-- 147 D+ A + GI + N P + ++AE + + L LLR + + A+ G + K AG+F Sbjct: 83 DMTAMKQYGIRLSNVPAYSPAAIAEFALTDTLYLLRNMGKVQAQLQAGDYEK--AGTFIG 140 Query: 148 -EARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPL-GNATQVQHLS--DLLNM 203 E + +G++G GHIG L + G V YD P+ G+ ++S DL Sbjct: 141 KELGQQTVGVMGTGHIGQVAIKLFKGFGAKVIAYD---PYPMKGDHPDFDYVSLEDLFKQ 197 Query: 204 SDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAI 263 SDV+ LHVP +++ +LMKPG+++IN +R ++D A+ L S LAG I Sbjct: 198 SDVIDLHVPGIEQNTHIINEAAFNLMKPGAIVINTARPNLIDTQAMLSNLKSGKLAGVGI 257 Query: 264 DVFPTEP---------ATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIK 314 D + E + DP L NV+L+PHI T+ A N+ L+ Sbjct: 258 DTYEYETEDLLNLAKHGSFKDPLWDELLGMPNVVLSPHIAYYTETAVHNMVYFSLQHLVD 317 Query: 315 YSDNGSTLSAVNFP 328 + G T + V P Sbjct: 318 FLTKGETSTEVTGP 331 >4XKJ-A nrPDB Length = 335 Score = 111 bits (277), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 84/233 (36%), Positives = 123/233 (52%), Gaps = 17/233 (7%) Query: 85 GTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAA 144 G + +DL+ A++RG+ V N P + SVAEL + + + L+R +P +A+ + Sbjct: 79 GYDMIDLEQASERGLVVTNVPAYSPNSVAELALTQTMRLIRNLPLFDARGAEQDFRWAGL 138 Query: 145 GSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMS 204 + E R +GIIG G IG + L ++LG V DI ++ L + +LL + Sbjct: 139 MAREIRSLTVGIIGAGRIGGTVARLFKALGATVIANDIVERVELKDIVTYVSKEELLQAA 198 Query: 205 DVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAID 264 DVV+LHVP ST ++ A ++LMK ++LINASRG VVD AL AL +K +AGAA+D Sbjct: 199 DVVTLHVPLMDSTTQLIDADALALMKNDAVLINASRGPVVDTDALIAALQNKQIAGAALD 258 Query: 265 VFPTEPATNSDPFTSPLC-------------EFDNVLLTPHIGGSTQEAQENI 304 E F LC NVL+TPHIG T +A +N+ Sbjct: 259 TLNGE----EHFFNQDLCGKELPSEQLKVLRTLPNVLITPHIGFYTNKAVQNM 307 >2DBZ-A nrPDB Length = 334 Score = 110 bits (275), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 91/266 (34%), Positives = 135/266 (50%), Gaps = 22/266 (8%) Query: 64 HLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLL 123 + ++V A KL + + +G + +D++ A KRGI V N P T + A+L LL Sbjct: 56 RIDKEVFENAPKLRIVANYAVGYDNIDIEEATKRGIYVTNTPDVLTDATADLAFALLLAT 115 Query: 124 LRGVPEANAKAHRGVWNKLAAG-------SFEARGKKLGIIGYGHIGTQLGILAESLGMY 176 R V + + G W K ++ GK +GIIG G IG + A+ M Sbjct: 116 ARHVVKGDRFVRSGEWKKRGVAWHPKWFLGYDVYGKTIGIIGLGRIGQAIAKRAKGFNMR 175 Query: 177 VYFY------DIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMK 230 + +Y ++E +L NA + + L DLL SD V L VP T +++ + + LMK Sbjct: 176 ILYYSRTRKEEVEREL---NA-EFKPLEDLLRESDFVVLAVPLTRETYHLINEERLKLMK 231 Query: 231 PGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLT 290 ++LIN +RG VVD AL AL +AGA +DVF EP N + L + DNV+LT Sbjct: 232 KTAILINIARGKVVDTNALVKALKEGWIAGAGLDVFEEEPYYNEE-----LFKLDNVVLT 286 Query: 291 PHIGGSTQEAQENIGLEVAGKLIKYS 316 PHIG ++ A+E + VA LI + Sbjct: 287 PHIGSASFGAREGMAELVAKNLIAFK 312 >2OME-A nrPDB Length = 336 Score = 109 bits (273), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 75/229 (32%), Positives = 113/229 (49%), Gaps = 19/229 (8%) Query: 85 GTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLR-------GVPEANAKAHRG 137 G + VD+ AA + GI V N P + A+ I +L L R + E Sbjct: 79 GYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRVQSVE 138 Query: 138 VWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYD------IENKLPLGNA 191 ++A+G+ RG+ LG+IG+G G + + A++ G V FYD IE L Sbjct: 139 QIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSL---GV 195 Query: 192 TQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCD 251 +V L DLL SD VSLH N +++ I M+ G+ L+NA+RG +VD AL Sbjct: 196 QRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQ 255 Query: 252 ALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEA 300 AL + GAA+DV +EP + + PL + N++ TPH +++A Sbjct: 256 ALKEGRIRGAALDVHESEPFSFAQ---GPLKDAPNLICTPHTAWYSEQA 301 >6ABJ-A nrPDB Length = 345 Score = 109 bits (273), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 80/259 (30%), Positives = 120/259 (46%), Gaps = 15/259 (5%) Query: 74 EKLVAIGCFCI-----GTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVP 128 E+L A G + G N VDL AA G+PV + P + +VAE +G +L L R + Sbjct: 78 ERLAAGGTRLVALRSAGYNHVDLAAAEALGLPVVHVPAYSPHAVAEHAVGLILTLNRRLH 137 Query: 129 EANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYD-IENKLP 187 A + G ++ F+ GK++G+IG G IG + G + YD N Sbjct: 138 RAYNRTREGDFSLHGLTGFDLHGKRVGVIGTGQIGETFARIMAGFGCELLAYDPYPNPRI 197 Query: 188 LGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIP 247 + L LL SD+VSLH P T++++ A+ ++ MKPG++LIN RG +V+ Sbjct: 198 QALGGRYLALDALLAESDIVSLHCPLTADTRHLIDAQRLATMKPGAMLINTGRGALVNAA 257 Query: 248 ALCDALASKHLAGAAIDVFPTEPATN---------SDPFTSPLCEFDNVLLTPHIGGSTQ 298 AL +AL S L +DV+ E D + L F NV++T H T+ Sbjct: 258 ALIEALKSGQLGYLGLDVYEEEADIFFEDRSDQPLQDDVLARLLSFPNVVVTAHQAFLTR 317 Query: 299 EAQENIGLEVAGKLIKYSD 317 EA I + + D Sbjct: 318 EALAAIADTTLDNIAAWQD 336 >2YQ5-A nrPDB Length = 343 Score = 108 bits (271), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 79/265 (29%), Positives = 126/265 (47%), Gaps = 20/265 (7%) Query: 57 IGLRSRTHLTEDVINAAEKLVAIGCFCIGT-----NQVDLDAAAKRGIPVFNAPFSNTRS 111 + L+ + E+V+ +KL G CIG N ++ D K + V N P + R+ Sbjct: 49 VSLKPLGPVDEEVV--YQKLSEYGVKCIGLRIVGFNTINFDWTKKYNLLVTNVPVYSPRA 106 Query: 112 VAELVIGELLLLLRGVPEANAKA---HRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGI 168 +AE+ + + + LLR + E + H W S E +G+IG GHIG+ + Sbjct: 107 IAEMTVTQAMYLLRKIGEFRYRMDHDHDFTWPSNLI-SNEIYNLTVGLIGVGHIGSAVAE 165 Query: 169 LAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISL 228 + ++G V YD+ +L +D+VSLH P PST+NM+G K++ Sbjct: 166 IFSAMGAKVIAYDVAYNPEFEPFLTYTDFDTVLKEADIVSLHTPLFPSTENMIGEKQLKE 225 Query: 229 MKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPA-------TNSD--PFTS 279 MK + LIN +RG +VD AL AL +AGA +D E + T+S+ Sbjct: 226 MKKSAYLINCARGELVDTGALIKALQDGEIAGAGLDTLAGESSYFGHTGLTDSEIPEDYK 285 Query: 280 PLCEFDNVLLTPHIGGSTQEAQENI 304 L + NV++TPH T+ + N+ Sbjct: 286 TLAKMPNVVITPHSAFYTETSIRNM 310 >1HL3-A nrPDB Length = 358 Score = 107 bits (266), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 74/241 (30%), Positives = 118/241 (48%), Gaps = 19/241 (7%) Query: 85 GTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVW----- 139 G + +D+ +A GI V N P ++ A+ + +L L R + G Sbjct: 98 GFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRTTWLHQALREGTRVQSVE 157 Query: 140 --NKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYD------IENKLPLGNA 191 ++A+G+ RG+ LGIIG G +G + + A++ G V FYD IE L L Sbjct: 158 QIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGIERALGL--- 214 Query: 192 TQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCD 251 +V L DLL SD V+LH N +++ + M+ G+ L+N +RG +VD AL Sbjct: 215 QRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQ 274 Query: 252 ALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGK 311 AL + GAA+DV +EP + S PL + N++ TPH +++A + E A + Sbjct: 275 ALKEGRIRGAALDVHESEPFSFSQ---GPLKDAPNLICTPHAAWYSEQASIEMREEAARE 331 Query: 312 L 312 + Sbjct: 332 I 332 >4NFY-A nrPDB Length = 307 Score = 106 bits (265), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 85/308 (27%), Positives = 138/308 (44%), Gaps = 37/308 (12%) Query: 25 ESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCI 84 E L AG+ + K E + E I+DA + +RS + E++I A EK+ I Sbjct: 21 EILEKAGHEVVMIEK-YKKKEDVIERIKDADGVIVRS-DKIDEEIIKAGEKVKIIVRAGA 78 Query: 85 GTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLR-GVPEANAKAHRGVWNKLA 143 G + +D++A + I V N P N VAEL IG ++ R G E + Sbjct: 79 GYDNIDIEACNQGKIVVMNTPGQNRNGVAELCIGMMIFGFRKGFKEGKGR---------- 128 Query: 144 AGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLP-LGNATQVQHLSDLLN 202 E + K LGI G G++G ++ +AE +GM + YD P + QV+ + +L Sbjct: 129 ----ELKDKTLGICGCGYVGKRVKEIAEGIGMKIKVYD-----PFITTENQVKKIEELFE 179 Query: 203 MSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAA 262 V+SLH+P TK +G + I + G ++ N +R ++D L + + Sbjct: 180 ECQVISLHLPLTKETKGKIGYELIKKLPYGGMICNTARKEIIDEEGLIRIMREREDLIYI 239 Query: 263 IDVFPTEPATNSD----PFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDN 318 DV PT N++ F +P+ IG T+E+ N G+ A ++ + N Sbjct: 240 TDVAPTSKVFNNEFKGRFFATPI----------KIGAETEESNINAGMAAASQICDFFTN 289 Query: 319 GSTLSAVN 326 G+ VN Sbjct: 290 GTVKFQVN 297 >1GDH-A nrPDB Length = 320 Score = 105 bits (262), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 73/242 (30%), Positives = 109/242 (45%), Gaps = 20/242 (8%) Query: 74 EKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAK 133 E + I + IG + +DLDA RGI V NAP T + AE+ +LLL G + Sbjct: 66 ENIKCISTYSIGFDHIDLDACKARGIKVGNAPHGVTVATAEIA----MLLLLGSARRAGE 121 Query: 134 AHRGV-------WNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKL 186 + + W L + K LGI G+G IG L A+ M + ++D Sbjct: 122 GEKMIRTRSWPGWEPLELVGEKLDNKTLGIYGFGSIGQALAKRAQGFDMDIDYFDTHRAS 181 Query: 187 PLGNATQVQHLSD----LLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGT 242 A+ D LL++S SL+ P P T+ I + G++++N +RG Sbjct: 182 SSDEASYQATFHDSLDSLLSVSQFFSLNAPSTPETRYFFNKATIKSLPQGAIVVNTARGD 241 Query: 243 VVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQE 302 +VD + AL + LA A DVF EP N + P N L PHIG + +A+E Sbjct: 242 LVDNELVVAALEAGRLAYAGFDVFAGEPNINEGYYDLP-----NTFLFPHIGSAATQARE 296 Query: 303 NI 304 ++ Sbjct: 297 DM 298 >3WR5-A nrPDB Length = 406 Score = 103 bits (258), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 76/245 (31%), Positives = 126/245 (51%), Gaps = 12/245 (4%) Query: 64 HLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLL 123 +LT + I A+ L IG++ VDL +A RGI V + N+ SVAE V+ +L L Sbjct: 108 YLTPERIAKAKNLKLALTAGIGSDHVDLQSAIDRGITVAEVTYCNSISVAEHVVMMILGL 167 Query: 124 LRGVPEANAKAHRGVWN--KLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYD 181 +R ++ A +G WN S++ G +G + G IG + + +++ D Sbjct: 168 VRNYIPSHDWARKGGWNIADCVEHSYDLEGMTVGSVAAGRIGLAVLRRLAPFDVKLHYTD 227 Query: 182 IENKLPLGNATQ---VQHLS--DLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLI 236 ++LP + V H + D+ DVV+L+VP +P T++M+ + + L K G+ ++ Sbjct: 228 -RHRLPEAVEKELGLVWHDTREDMYPHCDVVTLNVPLHPETEHMINDETLKLFKRGAYIV 286 Query: 237 NASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGS 296 N +RG + D A+ A+ S LAG A DV+ +PA P+ + E +TPHI G+ Sbjct: 287 NTARGKLADRDAIVRAIESGQLAGYAGDVWFPQPAPKDHPWRTMKWEG----MTPHISGT 342 Query: 297 TQEAQ 301 + AQ Sbjct: 343 SLSAQ 347 >4LSW-A nrPDB Length = 318 Score = 103 bits (256), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 78/251 (31%), Positives = 117/251 (46%), Gaps = 7/251 (2%) Query: 57 IGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELV 116 I R + +I A L I + +G + VDL A +RGI V N P T VA+L Sbjct: 49 IATRGELGASRALIEACPNLELISVYGVGYDAVDLAACRERGIQVTNTPDVLTGDVADLG 108 Query: 117 IGELLLLLRGVPEANAKAHRGVWNKLAAGSFEAR--GKKLGIIGYGHIGTQLGILAESLG 174 + +L RG+ A A G W + R G++ G++G G IG ++ Sbjct: 109 VAMMLAQSRGIIGAETWARSGKWAAEGLYPLKRRVFGRRAGVLGLGRIGFEVARRLAGFD 168 Query: 175 MYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSL 234 M + + DI K + T V+ L D + + + + +T++++G I + P + Sbjct: 169 MQISYSDIAPKSYAPDWTFVEDAVTLARDVDFLFVTLAASAATRHIVGRDVIEALGPEGM 228 Query: 235 LINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIG 294 LIN SR + +D AL ALA L AA+DVF EP N DP + NVLL PH Sbjct: 229 LINISRASNIDEEALIAALADGRLGSAALDVFEGEP--NFDP---RFRDLPNVLLQPHHA 283 Query: 295 GSTQEAQENIG 305 T E ++ +G Sbjct: 284 SGTIETRKAMG 294 >2GO1-A nrPDB Length = 401 Score = 102 bits (253), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 74/246 (30%), Positives = 124/246 (50%), Gaps = 14/246 (5%) Query: 64 HLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLL 123 +LT + I A+ L IG++ VDL +A R + V + N+ SVAE V+ +L L Sbjct: 103 YLTPERIAKAKNLKLALTAGIGSDHVDLQSAIDRNVTVAEVTYCNSISVAEHVVMMILSL 162 Query: 124 LRGVPEANAKAHRGVWN--KLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYD 181 +R ++ A +G WN + +++ +G + G IG + +++++ D Sbjct: 163 VRNYLPSHEWARKGGWNIADCVSHAYDLEAMHVGTVAAGRIGLAVLRRLAPFDVHLHYTD 222 Query: 182 IENKLPLG-----NATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLI 236 ++LP N T D+ + DVV+L+ P +P T++M+ + + L K G+ ++ Sbjct: 223 -RHRLPESVEKELNLTWHATREDMYPVCDVVTLNCPLHPETEHMINDETLKLFKRGAYIV 281 Query: 237 NASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPF-TSPLCEFDNVLLTPHIGG 295 N +RG + D A+ AL S LAG A DV+ +PA P+ T P +TPHI G Sbjct: 282 NTARGKLCDRDAVARALESGRLAGYAGDVWFPQPAPKDHPWRTMPYNG-----MTPHISG 336 Query: 296 STQEAQ 301 +T AQ Sbjct: 337 TTLTAQ 342 >2DLD-A nrPDB Length = 337 Score = 100 bits (250), Expect = 9e-22, Method: Compositional matrix adjust. Identities = 68/231 (29%), Positives = 107/231 (46%), Gaps = 10/231 (4%) Query: 84 IGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLA 143 +G + +D+D A + G + N P + ++AE + +LR + K + Sbjct: 79 VGVDNIDMDKAKELGFQITNVPVYSPNAIAEHAAIQAARVLRQDKRMDEKMAKRDLRWAP 138 Query: 144 AGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDI-ENKLPLGNATQVQHLSDLLN 202 E R + +G++G GHIG + E G V YDI +N V L DL Sbjct: 139 TIGREVRDQVVGVVGTGHIGQVFMRIMEGFGAKVIAYDIFKNPELEKKGYYVDSLDDLYK 198 Query: 203 MSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAA 262 +DV+SLHVP+ P+ +M+ K I+ MK G +++N SRG +VD A+ L S + G Sbjct: 199 QADVISLHVPDVPANVHMINDKSIAEMKDGVVIVNCSRGRLVDTDAVIRGLDSGKIFGFV 258 Query: 263 IDVFPTEPATNS---------DPFTSPLCEFDNVLLTPHIGGSTQEAQENI 304 +D + E + D + L + NVL+TPH T A N+ Sbjct: 259 MDTYEDEVGVFNKDWEGKEFPDKRLADLIDRPNVLVTPHTAFYTTHAVRNM 309 >3JTM-A nrPDB Length = 351 Score = 100 bits (249), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 69/224 (30%), Positives = 115/224 (51%), Gaps = 10/224 (4%) Query: 84 IGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWN--K 141 IG++ +DL AAA G+ V SN SVAE + +L+L+R + +G WN Sbjct: 95 IGSDHIDLQAAAAAGLTVAEVTGSNVVSVAEDELMRILILMRNFVPGYNQVVKGEWNVAG 154 Query: 142 LAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPL----GNATQVQHL 197 +A +++ GK +G +G G IG L + G + ++D P A V+ L Sbjct: 155 IAYRAYDLEGKTIGTVGAGRIGKLLLQRLKPFGCNLLYHDRLQMAPELEKETGAKFVEDL 214 Query: 198 SDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKH 257 +++L DV+ +++P T+ M + I +K G L++N +RG +++ A+ DA+ S H Sbjct: 215 NEMLPKCDVIVINMPLTEKTRGMFNKELIGKLKKGVLIVNNARGAIMERQAVVDAVESGH 274 Query: 258 LAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQ 301 + G + DV+ +PA P P N +TPH G+T +AQ Sbjct: 275 IGGYSGDVWDPQPA----PKDHPWRYMPNQAMTPHTSGTTIDAQ 314 >3WNV-A nrPDB Length = 330 Score = 100 bits (249), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 84/263 (31%), Positives = 136/263 (51%), Gaps = 13/263 (4%) Query: 68 DVINAAEKLVAIGCFC-IGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRG 126 ++I+A K V C G + +D+DAA + GI + + P + + A++ I ++ LR Sbjct: 70 ELISALPKSVKYICHNGAGYDNIDVDAATEAGIAISSTPIAVNNATADVAIFLMIGALRQ 129 Query: 127 --VPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIEN 184 VP +A G W+ + GK LGI+G G IG ++ A + GM + +++ N Sbjct: 130 AYVPITAIRA--GEWHGKTTLGHDPNGKTLGILGMGGIGREVARRARAFGMNIIYHN-RN 186 Query: 185 KLP--LGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGT 242 KLP L + + +LL SDV SL++ N ST++++G KE++ MK G +++N +RG Sbjct: 187 KLPPELEDGAKYVSFDELLAQSDVFSLNLALNASTRHIIGEKELAKMKDGVVIVNTARGA 246 Query: 243 VVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQE 302 ++D AL AL S +A +DV+ EP +P +L PHIG T E Q+ Sbjct: 247 LIDEKALVRALESGKVASVGLDVYENEPQVEPGLLNNP-----RAMLLPHIGTMTYETQK 301 Query: 303 NIGLEVAGKLIKYSDNGSTLSAV 325 + L V L + G L+ V Sbjct: 302 EMELLVLNNLRSAIEKGELLTQV 324 >4EBF-A nrPDB Length = 334 Score = 99.8 bits (247), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 91/326 (27%), Positives = 143/326 (43%), Gaps = 14/326 (4%) Query: 12 KFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVIN 71 K ++ VH++ L+ L L E++ RDA + + D + Sbjct: 5 KLVITHRVHEEILQLLAPHCELITNQTDSTLTREEILRRCRDAQAMMAFMPDRVDADFLQ 64 Query: 72 AAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEAN 131 A +L IGC G + D+DA RG+ + P T AEL IG + L R + A+ Sbjct: 65 ACPELRVIGCALKGFDNFDVDACTARGVWLTFVPDLLTVPTAELAIGLAVGLGRHLRAAD 124 Query: 132 AKAHRGV---WNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFY-----DIE 183 A G W G+ +G +G G IG + + G + ++ D + Sbjct: 125 AFVRSGQFRGWQPRFYGT-GLDNATVGFLGMGAIGLAMADRLQGWGATLQYHAAKALDTQ 183 Query: 184 NKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTV 243 + LG QV S+L SD + L +P N T +++ A+ ++L++PG+LL+N RG+V Sbjct: 184 TEQRLG-LRQVA-CSELFASSDFILLALPLNADTLHLVNAELLALVRPGALLVNPCRGSV 241 Query: 244 VDIPALCDALASKHLAGAAIDVFPTEPATNSD---PFTSPLCEFDNVLLTPHIGGSTQEA 300 VD A+ AL L G A DVF E +D L N L TPHIG + + Sbjct: 242 VDEAAVLAALERGQLGGYAADVFEMEDWARADRPQQIDPALLAHPNTLFTPHIGSAVRAV 301 Query: 301 QENIGLEVAGKLIKYSDNGSTLSAVN 326 + I A +++ ++AVN Sbjct: 302 RLEIERCAAQNILQALAGERPINAVN 327 >2WWR-A nrPDB Length = 330 Score = 99.4 bits (246), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 80/276 (28%), Positives = 122/276 (44%), Gaps = 11/276 (3%) Query: 45 EQLKESIRDAHFIGLRSRTHLTEDVINAA-EKLVAIGCFCIGTNQVDLDAAAKRGIPVFN 103 ++L+ + AH + H+ + +++AA L I +G + + LD KRGI V Sbjct: 45 KELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGY 104 Query: 104 APFSNTRSVAELVIGELLLLLRGVPEANAKAHRG---VWNKLAAGSFEARGKKLGIIGYG 160 P T + AEL + LL R +PEA + G W L + +GIIG G Sbjct: 105 TPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLG 164 Query: 161 HIGTQLGILAESLGMYVYFYDIENKLPLGNAT-QVQHLS--DLLNMSDVVSLHVPENPST 217 IG + + G+ + Y P A Q + +S +L SD + + P+T Sbjct: 165 RIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPAT 224 Query: 218 KNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPF 277 + + MK ++ IN SRG VV+ L ALAS +A A +DV EP P Sbjct: 225 EGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPL----PT 280 Query: 278 TSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLI 313 PL N ++ PHIG +T + + L A L+ Sbjct: 281 NHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLL 316 >5UOG-A nrPDB Length = 344 Score = 98.6 bits (244), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 91/316 (28%), Positives = 142/316 (44%), Gaps = 15/316 (4%) Query: 14 LLVEG-VHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVINA 72 +LV G ++ + LE L + + + D + +RD I + + L +++A Sbjct: 28 ILVPGKINPRVLERLPEM-FETVRIERA--DAALVTADMRDVSGIAVSGK--LPVPLMDA 82 Query: 73 AEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANA 132 L + F +G + VD+ AA RGI V N P T VA+ IG LL LR +P+A Sbjct: 83 FPSLEIVANFGVGYDGVDVSRAAARGIVVTNTPDVLTEEVADTAIGLLLNTLRLLPQAEQ 142 Query: 133 KAHRGVWNKLAA---GSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLG 189 +G W + A RG+ +G+ G G IG + E+ G+ + ++ + LG Sbjct: 143 WLRQGRWVREGAFPLSPLSLRGRTVGLFGLGRIGLAIARRLEAFGVSIAYHTRTPREGLG 202 Query: 190 NATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPAL 249 T L + D + + VP ST + A +S + P +LIN RG+ VD AL Sbjct: 203 -FTYHPTLVGMAEAVDTLIVIVPGTASTLKAVNADVLSALGPKGVLINVGRGSTVDEAAL 261 Query: 250 CDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVA 309 AL + +AGA +DVF EP L F NV L PH+ ++ + + V Sbjct: 262 VTALQNGTIAGAGLDVFENEPNV-----PEALLSFPNVSLLPHVASASVVTRNAMSDLVV 316 Query: 310 GKLIKYSDNGSTLSAV 325 L + G L+ V Sbjct: 317 DNLKAWFSTGEALTPV 332 >1J49-A nrPDB Length = 333 Score = 97.1 bits (240), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 75/264 (28%), Positives = 117/264 (44%), Gaps = 19/264 (7%) Query: 84 IGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLA 143 +G + +D+ A + G + N P + ++AE + +LR + K R Sbjct: 79 VGVDNIDMAKAKELGFQITNVPVYSPNAIAEHAAIQAARILRQDKAMDEKVARHDLRWAP 138 Query: 144 AGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPL-GNATQVQHLSDLLN 202 E R + +G++G GHIG + E G V YDI L V L DL Sbjct: 139 TIGREVRDQVVGVVGTGHIGQVFMQIMEGFGAKVITYDIFRNPELEKKGYYVDSLDDLYK 198 Query: 203 MSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAA 262 +DV+SLHVP+ P+ +M+ + I+ MK +++N SRG +VD A+ L S + G A Sbjct: 199 QADVISLHVPDVPANVHMINDESIAKMKQDVVIVNVSRGPLVDTDAVIRGLDSGKIFGYA 258 Query: 263 IDVFPTEPATNSDPFT---------SPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLI 313 +DV+ E ++ + + L NVL+TPH T A N+ ++ Sbjct: 259 MDVYEGEVGIFNEDWEGKEFPDARLADLIARPNVLVTPHTAFYTTHAVRNM-------VV 311 Query: 314 KYSDNGSTLSAVNFPEVSLPLHGG 337 K DN L V E P+ G Sbjct: 312 KAFDN--NLELVEGKEAETPVKVG 333 >4XYG-A nrPDB Length = 391 Score = 96.3 bits (238), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 69/227 (30%), Positives = 114/227 (50%), Gaps = 16/227 (7%) Query: 84 IGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWN--K 141 IG++ VDL+AA K GI V FSN VAE + +L L+R ++ A G WN Sbjct: 123 IGSDHVDLNAAIKAGITVAEETFSNGICVAEHAVMMILALVRNYLPSHKIAEEGGWNIAD 182 Query: 142 LAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYF-------YDIENKLPLGNATQV 194 + S++ G +G + G IG + + + +++ IE++L L Sbjct: 183 CVSRSYDLEGMHVGTVAAGRIGLAVLRRLKPFDVKLHYTARHRSPRAIEDELGLTYHATA 242 Query: 195 QHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALA 254 + ++++ DV+S+H P P+T+++ AK ++ M+ GS L+N +R + D + AL Sbjct: 243 EEMAEV---CDVISIHAPLYPATEHLFNAKVLNKMRHGSYLVNTARAEICDRDDIVRALE 299 Query: 255 SKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQ 301 S LAG A DV+ +PA P P + +TPH+ GS+ Q Sbjct: 300 SGQLAGYAGDVWFPQPA----PANHPWRNMPHNGMTPHMSGSSLSGQ 342 >5Z1Z-A nrPDB Length = 329 Score = 95.9 bits (237), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 69/232 (29%), Positives = 105/232 (45%), Gaps = 10/232 (4%) Query: 83 CIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKL 142 C G N VDLDAA + G+ V P + +VAE IG ++ L R + A + ++ Sbjct: 76 CAGFNNVDLDAAKELGLKVVRVPAYDPEAVAEHAIGMMMTLNRRIHRAYQRTRDANFSLE 135 Query: 143 AAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYD-IENKLPLGNATQVQHLSDLL 201 F GK G+IG G IG + + + GM + +D + L + L L Sbjct: 136 GLTGFTMYGKTAGVIGTGKIGVAMLRILKGFGMRLLAFDPYPSAAALELGVEYVDLPTLF 195 Query: 202 NMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGA 261 + SDV+SLH P P +++ MK G +++N SRG ++D A +AL ++ + Sbjct: 196 SESDVISLHCPLTPENYHLLNEAAFDQMKNGVMIVNTSRGALIDSQAAIEALKNQKIGSL 255 Query: 262 AIDVFPT------EPATN---SDPFTSPLCEFDNVLLTPHIGGSTQEAQENI 304 +DV+ E +N D L NVL T H T EA +I Sbjct: 256 GMDVYENERDLFFEDKSNDVIQDDVFRRLSACHNVLFTGHQAFLTAEALTSI 307 >6IH4-A nrPDB Length = 338 Score = 95.1 bits (235), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 101/332 (30%), Positives = 145/332 (43%), Gaps = 17/332 (5%) Query: 10 KIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDV 69 K K +L VH + +E L A+ + L ++ +DA + + Sbjct: 2 KPKVVLTHWVHPEIIELLSASADVIPNTTRETLPRSEVIARAKDADALMAFMPDSIDSAF 61 Query: 70 INAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPE 129 + KL IG G + D++A + G+ + P T AEL IG LL L R + E Sbjct: 62 LEECPKLRVIGAALKGYDNFDVNACTRHGVWLTIVPDLLTIPTAELTIGLLLGLTRHMLE 121 Query: 130 ANAKAHRGV---WNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKL 186 + + G W GS GK LGI G G +G + M + + D ++ Sbjct: 122 GDRQIRSGHFQGWRPTLYGS-GLTGKTLGIRGMGAVGRAIAQRLAGFEMNLLYCD---EI 177 Query: 187 PLG----NATQVQH--LSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASR 240 PL A VQ L +LL D V VP T +++ A ++ MK GS LINA R Sbjct: 178 PLNAEQEKAWHVQRVTLDELLEKCDYVVPMVPMAAETLHLIDATALAKMKTGSYLINACR 237 Query: 241 GTVVDIPALCDALASKHLAGAAIDVFPTEPATNSD-PFTSPLCEFDN---VLLTPHIGGS 296 G+VVD A+ ALAS LAG A DVF E +D P P DN TPH+G + Sbjct: 238 GSVVDENAVIAALASGKLAGYAADVFEMEEWIRADRPQAIPKALLDNTAQTFFTPHLGSA 297 Query: 297 TQEAQENIGLEVAGKLIKYSDNGSTLSAVNFP 328 +E + I + A +I+ + A+N P Sbjct: 298 VKEVRLEIERQAAMNIIQALAGEKPMGAINQP 329 >3GG9-A nrPDB Length = 352 Score = 94.4 bits (233), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 78/275 (28%), Positives = 119/275 (43%), Gaps = 23/275 (8%) Query: 46 QLKESIRDAH-FIGLRSRTHLTEDVINAAEKLVAIG----CFCIGTNQVDLDAAAKRGIP 100 QL + D + +R RT +T +++ KL I +DL+A +G+ Sbjct: 41 QLAARVADVEALVLIRERTRVTRQLLDRLPKLKIISQTGRVSRDAGGHIDLEACTDKGVV 100 Query: 101 VFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEA----------R 150 V S + AEL ++ R +P+ A G W + S + Sbjct: 101 VLEGKGSPV-APAELTWALVMAAQRRIPQYVASLKHGAWQQSGLKSTTMPPNFGIGRVLK 159 Query: 151 GKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNAT--QVQHLSD-LLNMSDVV 207 G+ LGI GYG IG + + GM V + EN A V D L SDV+ Sbjct: 160 GQTLGIFGYGKIGQLVAGYGRAFGMNVLVWGRENSKERARADGFAVAESKDALFEQSDVL 219 Query: 208 SLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFP 267 S+H+ N T++++ +++ MKP +L +N SR +V+ + AL AAIDVF Sbjct: 220 SVHLRLNDETRSIITVADLTRMKPTALFVNTSRAELVEENGMVTALNRGRPGMAAIDVFE 279 Query: 268 TEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQE 302 TEP L +N + TPHIG +E+ E Sbjct: 280 TEPILQG----HTLLRMENCICTPHIGYVERESYE 310 >4CUK-A nrPDB Length = 338 Score = 94.4 bits (233), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 69/229 (30%), Positives = 100/229 (43%), Gaps = 12/229 (5%) Query: 83 CIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKL 142 C G N VDLDAA + G+ V P + +VAE IG ++ L R + A + ++ Sbjct: 76 CAGFNNVDLDAAKELGLQVVRVPAYSPEAVAEHAIGMMMTLNRRIHRAYQRTRDANFSLE 135 Query: 143 AAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYD-IENKLPLGNATQVQHLSDLL 201 F GK G+IG G IG + + GM + +D + L + L L Sbjct: 136 GLTGFTMHGKTAGVIGTGKIGVAALRILKGFGMRLLAFDPYPSTAALDLGVEYVDLQTLF 195 Query: 202 NMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGA 261 SDV+SLH P P +++ MK G ++IN SRG ++D A +AL ++ + Sbjct: 196 AESDVISLHCPLTPENYHLLNHAAFDQMKNGVMIINTSRGALIDSQAAIEALKNQKIGSL 255 Query: 262 AIDVFPTE----------PATNSDPFTSPLCEFDNVLLTPHIGGSTQEA 300 +DV+ E D F L NVL T H T EA Sbjct: 256 GMDVYENERDLFFEDKSVDVIQDDVFRR-LSACHNVLFTGHQAFLTAEA 303 >4S1V-D nrPDB Length = 332 Score = 93.6 bits (231), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 76/280 (27%), Positives = 126/280 (45%), Gaps = 14/280 (5%) Query: 31 GYTNIEFHKGALDDEQLKESIRDAH-FIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQV 89 G+ F+ D+ L E ++ + +R RT +TE+++ L I +N + Sbjct: 25 GHDVTVFNDSVSDETVLIERLKPFEALVLIRERTPITENLLAHLPNLKLISQTGKVSNHI 84 Query: 90 DLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNK---LAAGS 146 D+ + G+ V + + AEL +L R +P + H G W + L G Sbjct: 85 DVPLCERYGVTVLEG-IGSPVAPAELCWSLILAASRHLPSYIEQLHAGHWQQNGGLGLGR 143 Query: 147 FEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIE----NKLPLGNATQVQHLSDLLN 202 G+ LGI G G IG ++ GM + + E L LG ++ Sbjct: 144 -TLSGRTLGIWGLGKIGQRIAQFGHVFGMPILVWGSEASRQKALELGYQAAADK-AEFFA 201 Query: 203 MSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAA 262 +DV+SLH+ N +T+ ++ +++ MKP SL +N SR +V+ AL + + + AA Sbjct: 202 KADVLSLHLRLNDATRGIVTKQDLLAMKPDSLFVNTSRAELVESGALYSVMQANPMRQAA 261 Query: 263 IDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQE 302 +DV+ EPA P PL NVL PH+G + + E Sbjct: 262 VDVYENEPAL---PNNEPLLSLPNVLCAPHLGYVEKNSYE 298 >1XDW-A nrPDB Length = 331 Score = 90.9 bits (224), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 67/233 (28%), Positives = 114/233 (48%), Gaps = 15/233 (6%) Query: 85 GTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAA 144 GT+ +D + A + G P+ P + ++AEL + + ++LLR ++ + + K+ A Sbjct: 79 GTDHIDKEYAKELGFPMAFVPRYSPNAIAELAVTQAMMLLRHTAYTTSRTAKKNF-KVDA 137 Query: 145 GSF--EARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDI-ENKLPLGNATQVQHLSDLL 201 F E R +G++G G IG + +G V D+ E K TQV L ++L Sbjct: 138 FMFSKEVRNCTVGVVGLGRIGRVAAQIFHGMGATVIGEDVFEIKGIEDYCTQVS-LDEVL 196 Query: 202 NMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGA 261 SD++++H P ++ + MK G++L+N +RG +VD A+ +A+ S L G Sbjct: 197 EKSDIITIHAPYIKENGAVVTRDFLKKMKDGAILVNCARGQLVDTEAVIEAVESGKLGGY 256 Query: 262 AIDVFPTEPAT-----NSDPFTSPLCE-----FDNVLLTPHIGGSTQEAQENI 304 DV E + +PL E + VL+TPH+G T EA +N+ Sbjct: 257 GCDVLDGEASVFGKDLEGQKLENPLFEKLVDLYPRVLITPHLGSYTDEAVKNM 309 >6D4C-A nrPDB Length = 364 Score = 89.0 bits (219), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 69/249 (27%), Positives = 125/249 (50%), Gaps = 12/249 (4%) Query: 64 HLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRG--IPVFNAPFSNTRSVAELVIGELL 121 ++T++ I+ A+KL + +G++ +DLD + G I V SN S AE V+ +L Sbjct: 73 YITKERIDKAKKLKLVVVAGVGSDHIDLDYINQTGKKISVLEVTGSNVVSGAEHVLMTML 132 Query: 122 LLLRGVPEANAKAHRGVWN--KLAAGSFEARGKKLGIIGYGHIGTQ-LGILAESLGMYVY 178 +L+R A+ + W +A +++ GK + IG G IG + L L + Sbjct: 133 VLVRNFVPAHEQIINHDWEVAAIAKDAYDIEGKTIATIGAGRIGYRVLERLVPFNPKELL 192 Query: 179 FYDIENKLPLG-----NATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGS 233 +YD + LP A +V+++ +L+ +D+V+++ P + TK ++ + +S K G+ Sbjct: 193 YYDYQ-ALPKDAEEKVGARRVENIEELVAQADIVTINAPLHAGTKGLINKELLSKFKKGA 251 Query: 234 LLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFD-NVLLTPH 292 L+N +RG + + AL S L G DV+ +PA P+ ++ +TPH Sbjct: 252 WLVNTARGAICVAEDVAAALESGQLRGYGGDVWFPQPAPKDHPWRDMRNKYGAGNAMTPH 311 Query: 293 IGGSTQEAQ 301 G+T +AQ Sbjct: 312 YSGTTLDAQ 320 >2W2L-A nrPDB Length = 348 Score = 88.2 bits (217), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 71/228 (31%), Positives = 109/228 (47%), Gaps = 27/228 (11%) Query: 85 GTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLR-----------GVPEANAK 133 G + +DLDA +RG+ N+ + + ++L + +L + R G PE + Sbjct: 90 GFDWLDLDALNERGVAFANSRGAGDTATSDLALYLILSVFRLASYSERAARTGDPETFNR 149 Query: 134 AHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILA-ESLGMYVYFYDI-----ENKLP 187 H ++ + RG LG +G G I ++ A LGM + +YD+ E + Sbjct: 150 VHL----EIGKSAHNPRGHVLGAVGLGAIQKEIARKAVHGLGMKLVYYDVAPADAETEKA 205 Query: 188 LGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIP 247 LG A +V L +L SD VS+ VP T +++ + MKPGS ++N +RG V+ Sbjct: 206 LG-AERVDSLEELARRSDCVSVSVPYMKLTHHLIDEAFFAAMKPGSRIVNTARGPVISQD 264 Query: 248 ALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGG 295 AL AL S L A +DV EP + + L E +V LT HIGG Sbjct: 265 ALIAALKSGKLLSAGLDVHEFEPQVSKE-----LIEMKHVTLTTHIGG 307 >5MH6-A nrPDB Length = 308 Score = 85.9 bits (211), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 65/230 (28%), Positives = 107/230 (46%), Gaps = 9/230 (3%) Query: 79 IGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGV 138 + C G ++ + + G + N+ + +V E V G +L R + H Sbjct: 62 VHCIRAGYDEFPVGVYEEAGTYLTNSTGIHGTTVGETVAGYMLTFARRLHAYRDAQHDHA 121 Query: 139 WN-KLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQV--- 194 W+ F G+++ ++G G +G + A +LGM V P+ N + V Sbjct: 122 WDLPRYEEPFTLAGERVCVVGLGTLGRGVVDRAAALGMEVVGVRRSGD-PVDNVSTVYTP 180 Query: 195 QHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALA 254 L + + + V L P T+ M+ A E M+ + L+N +RG VV L AL Sbjct: 181 DRLHEAIADARFVVLATPLTDETEGMVAAPEFETMREDASLVNVARGPVVVESDLVAALD 240 Query: 255 SKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENI 304 S +AGAA+DVF EP P SPL +F++VL+TPH+ +T + E++ Sbjct: 241 SGDIAGAALDVFSEEPL----PEDSPLWDFEDVLITPHVSAATSKYHEDV 286 >6ABI-A nrPDB Length = 358 Score = 85.1 bits (209), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 66/229 (28%), Positives = 104/229 (45%), Gaps = 12/229 (5%) Query: 83 CIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKL 142 C G N V L +R V P + ++AE +G +L + R + +A + G ++ Sbjct: 102 CAGFNNVSLKDVNER-FKVVRVPAYSPHAIAEYTVGLILAVNRKINKAYVRTREGNFSIN 160 Query: 143 AAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLS--DL 200 + K GIIG G IG L + M V YD+ + + +++S +L Sbjct: 161 GLMGIDLYEKTAGIIGTGKIGQILIKILRGFDMKVIAYDLFPNQKVADELGFEYVSLDEL 220 Query: 201 LNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAG 260 SD++SL+ P TK M+ + + MK G +L+N RG ++D L +AL K + Sbjct: 221 YANSDIISLNCPLTKDTKYMINRRSMLKMKDGVILVNTGRGMLIDSADLVEALKDKKIGA 280 Query: 261 AAIDV-------FPTEPATN--SDPFTSPLCEFDNVLLTPHIGGSTQEA 300 A+DV F + +T D L F NVL+T H T+EA Sbjct: 281 VALDVYEEEENYFFEDKSTQVIEDDILGRLLSFYNVLITSHQAYFTKEA 329 >5DT9-A nrPDB Length = 387 Score = 83.6 bits (205), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 76/258 (29%), Positives = 112/258 (43%), Gaps = 31/258 (12%) Query: 49 ESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSN 108 + + D + +RS T + + ++ A +L +G G + VD +RGI AP N Sbjct: 39 DDLIDVDALMIRSVTKVNDALLAKANRLKFVGTATAGMDHVDQALLRERGIFFTAAPGCN 98 Query: 109 TRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGI 168 VAE V L++L + F K +GIIG G +G+ L Sbjct: 99 KVGVAEYVFSVLMVLAQ------------------QQGFSVFDKTVGIIGAGQVGSYLAK 140 Query: 169 LAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVP-----ENPSTKNMMGA 223 +GM V D K G+ + L LL +DV++LH P E P T +++ A Sbjct: 141 CLSGIGMKVLLND-PPKQAQGDEREFTELETLLKQADVITLHTPITRGGEWP-THHLIDA 198 Query: 224 KEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCE 283 + ++ +LINA+RG VVD AL L A +DVF EP + + PL Sbjct: 199 AILEQLRSDQILINAARGPVVDNAALKARLQQGDGFTAVLDVFEFEPQVDMELL--PLLA 256 Query: 284 FDNVLLTPHIGGSTQEAQ 301 F TPHI G E + Sbjct: 257 F----ATPHIAGYGLEGK 270 >3OET-A nrPDB Length = 381 Score = 78.2 bits (191), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 75/257 (29%), Positives = 117/257 (45%), Gaps = 30/257 (11%) Query: 49 ESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSN 108 E + A + +RS T + E +++ + +G GT+ VD + GI AP N Sbjct: 36 EELNHADALMVRSVTKVNESLLSGT-PINFVGTATAGTDHVDEAWLKQAGIGFSAAPGCN 94 Query: 109 TRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGI 168 +V E V LL+L A R F R + +GI+G G++G++L Sbjct: 95 AIAVVEYVFSALLML----------AERD--------GFSLRDRTIGIVGVGNVGSRLQT 136 Query: 169 LAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVP--ENPSTKNMMGAKE- 225 E+LG+ D + G+ + L +L+ +DV++ H P ++ K + A E Sbjct: 137 RLEALGIRTLLCD-PPRAARGDEGDFRTLDELVQEADVLTFHTPLYKDGPYKTLHLADET 195 Query: 226 -ISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEF 284 I +KPG++LINA RG VVD AL L + +DV+ EP N + L Sbjct: 196 LIRRLKPGAILINACRGPVVDNAALLARLNAGQPLSVVLDVWEGEPDLN----VALLEAV 251 Query: 285 DNVLLTPHIGGSTQEAQ 301 D + T HI G T E + Sbjct: 252 D--IGTSHIAGYTLEGK 266 >3HG7-A nrPDB Length = 324 Score = 76.6 bits (187), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 59/206 (28%), Positives = 91/206 (44%), Gaps = 8/206 (3%) Query: 89 VDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFE 148 V LDA +R + N ++E V G LL L+R +P + + +W Sbjct: 80 VLLDARCRRDYQLTNVRGIFGPLMSEYVFGHLLSLMRQLPLYREQQKQRLWQSHPYQGL- 138 Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLG--NATQVQHLSDLLNMSDV 206 +G+ L I+G G IG + + GM V + G Q+ L+ +L +DV Sbjct: 139 -KGRTLLILGTGSIGQHIAHTGKHFGMKVLGVSRSGRERAGFDQVYQLPALNKMLAQADV 197 Query: 207 VSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVF 266 + +P T ++ A KPG++L N RG ++ L AL + L A +DVF Sbjct: 198 IVSVLPATRETHHLFTASRFEHCKPGAILFNVGRGNAINEGDLLTALRTGKLGMAVLDVF 257 Query: 267 PTEPATNSDPFTSPLCEFDNVLLTPH 292 EP P SPL N+++TPH Sbjct: 258 EQEPL----PADSPLWGQPNLIITPH 279 >2O4C-A nrPDB Length = 380 Score = 76.3 bits (186), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 72/235 (30%), Positives = 108/235 (45%), Gaps = 45/235 (19%) Query: 79 IGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGV 138 +G IGT+ +DLD A+ GI +AP N R V + V+G LL + Sbjct: 62 VGTCTIGTDHLDLDYFAEAGIAWSSAPGCNARGVVDYVLGCLLAMA-------------- 107 Query: 139 WNKLAAGSFEARGKKLGIIGYGHIGT-----QLGILAESLGMYVYFYDI--ENKLPLGNA 191 E RG L YG +G +L + LG V D + + P G Sbjct: 108 ---------EVRGADLAERTYGVVGAGQVGGRLVEVLRGLGWKVLVCDPPRQAREPDGEF 158 Query: 192 TQVQHLSDLLNMSDVVSLHVP-----ENPSTKNMMGAKEISLMKPGSLLINASRGTVVDI 246 ++ L L +DV+SLH P E+P T++++ ++ ++PG+ L+NASRG VVD Sbjct: 159 VSLERL---LAEADVISLHTPLNRDGEHP-TRHLLDEPRLAALRPGTWLVNASRGAVVDN 214 Query: 247 PALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQ 301 AL L A+DV+ EP +DP + C ++ TPHI G + E + Sbjct: 215 QALRRLLEGGADLEVALDVWEGEP--QADPELAARC----LIATPHIAGYSLEGK 263 >4HY3-A nrPDB Length = 365 Score = 75.9 bits (185), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 62/224 (27%), Positives = 99/224 (44%), Gaps = 10/224 (4%) Query: 87 NQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGS 146 N + + +RGI V VAE+ +G L L RG+ +A+ G G+ Sbjct: 109 NNMPYEVLFQRGIHVVTTGQVFAEPVAEIGLGFALALARGIVDADIAFQEGTELWGGEGN 168 Query: 147 FEAR---GKKLGIIGYGHIGTQLGILAESLGMYVYFYD--IENKLPLGNATQVQHLSDLL 201 AR G ++GI+G+G +G L + + +D + + N + L D+L Sbjct: 169 ASARLIAGSEIGIVGFGDLGKALRRVLSGFRARIRVFDPWLPRSMLEENGVEPASLEDVL 228 Query: 202 NMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGA 261 SD + + K +GA+ S M+ G+ I SR VVD AL A++S H+ A Sbjct: 229 TKSDFIFVVAAVTSENKRFLGAEAFSSMRRGAAFILLSRADVVDFDALMAAVSSGHIV-A 287 Query: 262 AIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIG 305 A DV+P EP P P+ + + H G+ A + +G Sbjct: 288 ASDVYPEEPL----PLDHPVRSLKGFIRSAHRAGALDSAFKKMG 327 >4XA8-A nrPDB Length = 320 Score = 74.7 bits (182), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 57/187 (30%), Positives = 92/187 (49%), Gaps = 8/187 (4%) Query: 109 TRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGI 168 ++ +A V+ +L R +P G W+ + + A ++G++G G +G + Sbjct: 104 SQMMASFVLFCVLRHARDIPTFERAQREGRWHYVHPRT--AAEIRVGVLGLGDLGAAAAL 161 Query: 169 LAESLGMYVYFYDIENKLPLGNAT--QVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEI 226 G V + K G + ++ L L S++V + +P P T+ +M A+ + Sbjct: 162 ELARHGFDVRGWSRTPKALEGVSCFHGLEALPGFLAGSEIVVVMLPLTPETRGLMNAERL 221 Query: 227 SLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDN 286 + + G+ IN +RG VVD AL AL S H+A A +DVF EP P SPL DN Sbjct: 222 AHLPRGAKFINVARGPVVDEAALIAALRSGHIAEATLDVFEVEPL----PVGSPLWAMDN 277 Query: 287 VLLTPHI 293 VL+TPH+ Sbjct: 278 VLVTPHL 284 >3EVT-A nrPDB Length = 324 Score = 72.0 bits (175), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 67/250 (26%), Positives = 108/250 (43%), Gaps = 10/250 (4%) Query: 75 KLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEA--NA 132 +L + G + + L A G+ V N + +++E V+ +L ++RG A N Sbjct: 61 QLKFVQVISAGVDYLPLKALQAAGVVVANTSGIHADAISESVLAAMLSVVRGYHAAWLNQ 120 Query: 133 KAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLP--LGN 190 + R W L + G++L I G G IG L A +LGM+V + Sbjct: 121 RGARQ-W-ALPMTTSTLTGQQLLIYGTGQIGQSLAAKASALGMHVIGVNTTGHPADHFHE 178 Query: 191 ATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALC 250 +D L ++ + +P P+T ++ + K +LIN RG VD AL Sbjct: 179 TVAFTATADALATANFIVNALPLTPTTHHLFSTELFQQTKQQPMLINIGRGPAVDTTALM 238 Query: 251 DALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAG 310 AL L+ AA+DV EP P PL + D+VL+TPHI G + + A Sbjct: 239 TALDHHQLSMAALDVTEPEPL----PTDHPLWQRDDVLITPHISGQIAHFRATVFPIFAA 294 Query: 311 KLIKYSDNGS 320 ++ +G+ Sbjct: 295 NFAQFVKDGT 304 >5C5I-A nrPDB Length = 316 Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 52/220 (23%), Positives = 92/220 (41%), Gaps = 10/220 (4%) Query: 110 RSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGIL 169 R++AE + L R +P A+ VW L E +G++G G +G + Sbjct: 101 RTMAEAALAWTYYLFRDMPAYAAQQRARVWKGLPYKRPER--TTVGVLGLGELGAAAALR 158 Query: 170 AESLGMYVYFYDIENKLPLGNATQV--QHLSDLLNMSDVVSLHVPENPSTKNMMGAKEIS 227 G V+ + K G + L +L +++ +P T+ ++ A+ ++ Sbjct: 159 LRDAGFDVHGWSRSPKEIAGVTCHAGEETLERMLGQVEILVCLLPLTGETRGLLDARRLA 218 Query: 228 LMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNV 287 + G+ ++N +RG ++D AL +AL S + A +DVF EP + PF V Sbjct: 219 CLPEGAQIVNFARGPILDSAALIEALDSGRIGHAVLDVFEVEPLPEASPFWG----HPKV 274 Query: 288 LLTPHIGGSTQEAQENIGLEVAGKLIKYSDNGSTLSAVNF 327 + PHI +T E V + Y G +V+ Sbjct: 275 TVLPHISAATD--PETASAIVGAHVADYRATGRIPPSVDL 312 >5TSD-A nrPDB Length = 322 Score = 62.8 bits (151), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 57/199 (28%), Positives = 87/199 (43%), Gaps = 12/199 (6%) Query: 107 SNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQL 166 S T ++E V+ + L+ LRG ++ R W KL A EA +G++G G +G Sbjct: 100 SLTTRMSEWVVMQCLMHLRGQYGHDSHQRRREWAKLIAP--EAAEVTVGVMGLGILGQDA 157 Query: 167 GILAESLGMYVYFYDIENKLPLGNAT-QVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKE 225 + +G V + K G T L L +D++ +P P T ++ Sbjct: 158 VAKLKVMGFNVIGWSRTRKTIEGVETFDAGELDRFLAKTDILVGLLPLTPETTGFYDSEL 217 Query: 226 IS-LMKPGSL----LINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSP 280 L + G+L INA RG + A+ L GA++DVF EP SP Sbjct: 218 FKKLRRDGALGQPVFINAGRGKSQIETDIVSAVREGTLGGASLDVFEVEPLATD----SP 273 Query: 281 LCEFDNVLLTPHIGGSTQE 299 L E +NV +TPH ++E Sbjct: 274 LWELENVFITPHDAAVSEE 292 >3KBO-A nrPDB Length = 315 Score = 61.6 bits (148), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 50/190 (26%), Positives = 86/190 (45%), Gaps = 8/190 (4%) Query: 114 ELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESL 173 E + ++L R + A ++ +W L + E +GI+G G +G ++ ++ Sbjct: 104 EYAVSQVLHWFRRFDDYQALKNQALWKPLPEYTREE--FSVGIMGAGVLGAKVAESLQAW 161 Query: 174 GMYVYFYDIENKLPLGNATQV--QHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKP 231 G + + K G + V + L LN + V+ +P T ++ ++ + + Sbjct: 162 GFPLRCWSRSRKSWPGVESYVGREELRAFLNQTRVLINLLPNTAQTVGIINSELLDQLPD 221 Query: 232 GSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTP 291 G+ ++N +RG V L AL S L GA +DVF EP P SPL V +TP Sbjct: 222 GAYVLNLARGVHVQEADLLAALDSGKLKGAMLDVFSQEPL----PQESPLWRHPRVAMTP 277 Query: 292 HIGGSTQEAQ 301 HI T+ A+ Sbjct: 278 HIAAVTRPAE 287 >4N18-A nrPDB Length = 332 Score = 55.5 bits (132), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 52/189 (27%), Positives = 76/189 (40%), Gaps = 14/189 (7%) Query: 114 ELVIGELLLLLRGVPEANAKAHRGVWN---KLAAGSFEARGKKLGIIGYGHIGTQLGILA 170 E + +L R A A W + AA F +GI+G G IG + Sbjct: 121 EYALWSVLWFQRHFDRALAHQRTQTWKLYPQRAAADFH-----IGIMGLGEIGGYIADQL 175 Query: 171 ESLGMYVYFYDIENKLPLGNATQV--QHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISL 228 LG V + K G + L L D + +P T+ ++ A + Sbjct: 176 ARLGYRVSGWSRSEKQLAGVTCYRGEEALDHFLGSLDGLINLLPLTAQTRGILAAPLFNR 235 Query: 229 MKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVL 288 + G++LIN RG + + AL S LAGA +DVFP EP D PL V+ Sbjct: 236 LPAGAVLINCGRGEHMVNDDVLAALESGQLAGAVLDVFPQEPLPADD----PLWRHPQVV 291 Query: 289 LTPHIGGST 297 +TPH+ + Sbjct: 292 ITPHMASAA 300 >4WEQ-A nrPDB Length = 341 Score = 52.0 bits (123), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 53/195 (27%), Positives = 84/195 (43%), Gaps = 12/195 (6%) Query: 109 TRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGI 168 T ++E V+ + LL LR A A + W L+ EA +GI+G G +G Sbjct: 121 TTRMSEWVMMQCLLHLRQHRAYEALAKKHEWRDLSQP--EAADVTVGIMGMGVLGQDAAR 178 Query: 169 LAESLGMYVYFYDIENKLPLGNAT-QVQHLSDLLNMSDVVSLHVPENPSTKNMMGAK--- 224 ++G V + ++ G T L L +D + +P P T+ + A Sbjct: 179 KLAAMGFKVIGWSRSKRVIEGVETYDAAGLDAFLGRTDFLVGLLPLTPDTRGIFNAALFA 238 Query: 225 EISLMKP--GSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLC 282 ++S P + INA RG + + L S L GA++DVF EP + F Sbjct: 239 KLSRNGPFGAPVFINAGRGGSQVEADILECLDSGVLGGASLDVFEREPLSPESRF----W 294 Query: 283 EFDNVLLTPHIGGST 297 + NV +TPH+ S+ Sbjct: 295 DMPNVYVTPHVAASS 309 >1QP8-A nrPDB Length = 303 Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 41/174 (23%), Positives = 78/174 (44%), Gaps = 11/174 (6%) Query: 150 RGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSL 209 +G+K+ ++G G IGT++G + +LG V + K G L + L + Sbjct: 123 QGEKVAVLGLGEIGTRVGKILAALGAQVRGFSRTPK--EGPWRFTNSLEEALREARAAVC 180 Query: 210 HVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVF--P 267 +P N T+ ++ + ++LM ++ +N R V+D + L + A DV+ Sbjct: 181 ALPLNKHTRGLVKYQHLALMAEDAVFVNVGRAEVLDRDGVLRILKERPQFIFASDVWWGR 240 Query: 268 TEPATNSDPFTSPLCEFDNVLLTPHIGG--STQEAQENIGLEVAGKLIKYSDNG 319 + A +++ F+ P NV+ TP + G + + +E LI Y+ G Sbjct: 241 NDFAKDAEFFSLP-----NVVATPWVAGGYGNERVWRQMVMEAVRNLITYATGG 289 >3GVX-A nrPDB Length = 290 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 59/266 (22%), Positives = 114/266 (42%), Gaps = 26/266 (9%) Query: 49 ESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSN 108 + I+D + +G R++ I G + +D++ + + NA + Sbjct: 38 QVIKDRYVLGKRTKM---------------IQAISAGVDHIDVNGIPENVVLCSNAG-AY 81 Query: 109 TRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGI 168 + SVAE LL + + E N G++ + + + GK LGI+GYG IG ++ Sbjct: 82 SISVAEHAFALLLAHAKNILENNELMKAGIFRQ--SPTTLLYGKALGILGYGGIGRRVAH 139 Query: 169 LAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISL 228 LA++ GM V Y + + + +DL SD V + +P T+ M+ ++ ++ Sbjct: 140 LAKAFGMRVIAY-TRSSVDQNVDVISESPADLFRQSDFVLIAIPLTDKTRGMVNSRLLAN 198 Query: 229 MKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVL 288 + ++N +R VV P + L + DV+ EP N + Sbjct: 199 ARKNLTIVNVARADVVSKPDMIGFLKERSDVWYLSDVWWNEPEITE-------TNLRNAI 251 Query: 289 LTPHIGGSTQEAQENIGLEVAGKLIK 314 L+PH+ G +I +++A + ++ Sbjct: 252 LSPHVAGGMSGEIMDIAIQLAFENVR 277 >6CMZ-A nrPDB Length = 466 Score = 36.6 bits (83), Expect = 0.022, Method: Compositional matrix adjust. Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 12/98 (12%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYD-IENKLPLGNATQVQHLSDLLNMSDVVSLH 210 K+L ++G G+IG +LGI+ LG+ V + E LP +A V+ ++D L V Sbjct: 179 KRLVVVGAGYIGLELGIVYRKLGVDVSVVEAAERVLPAYDAELVRPVADSLARLGV---- 234 Query: 211 VPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPA 248 + +G K + L K G++ + A+ G +PA Sbjct: 235 -------RLWLGHKVLGLDKHGAVRVQAADGAEQTLPA 265 >5NFR-A nrPDB Length = 320 Score = 33.5 bits (75), Expect = 0.16, Method: Compositional matrix adjust. Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 16/86 (18%) Query: 153 KLGIIGYGHIGTQLG--ILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLH 210 K+ +IG G IG +G L E+LG + YD+ +P G A ++H S +L ++ Sbjct: 3 KIALIGSGQIGAIVGELCLLENLGDLI-LYDVVPGIPQGKALDLKHFSTILGVN------ 55 Query: 211 VPENPSTKNMMGAKEISLMKPGSLLI 236 +N++G +I +K +++ Sbjct: 56 -------RNILGTNQIEDIKDADIIV 74 >6ES9-A nrPDB Length = 551 Score = 32.3 bits (72), Expect = 0.37, Method: Compositional matrix adjust. Identities = 34/137 (24%), Positives = 57/137 (41%), Gaps = 26/137 (18%) Query: 155 GIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDL--LNMSDVVSLHVP 212 G IG G +GT+ I AE L L T+ Q L L +++S V Sbjct: 242 GYIGVGSLGTRSEIAAE--------------LILCGGTEAQKAKWLPGLASGEILSTAVF 287 Query: 213 ENPSTKNMMGAKEISLMKPG---------SLLINASRGTVVDIPALCDALASKHLAGAAI 263 P+T + +G+ ++ G + + +A R V+ + A D + G ++ Sbjct: 288 TEPNTGSDLGSLRTRAVRDGEDWVVTGNKTWITHAQRTHVMTLLARTDP-ETTDWRGLSM 346 Query: 264 DVFPTEPATNSDPFTSP 280 + EP T+ DPF +P Sbjct: 347 FLAEKEPGTDDDPFPTP 363 >1PZF-A nrPDB Length = 331 Score = 32.3 bits (72), Expect = 0.39, Method: Compositional matrix adjust. Identities = 17/54 (31%), Positives = 29/54 (53%), Gaps = 1/54 (1%) Query: 150 RGKKLGIIGYGHIGTQLGILAESLGMY-VYFYDIENKLPLGNATQVQHLSDLLN 202 R KK+ +IG G IG +G L + V YD+ +P G A + H++ +++ Sbjct: 8 RRKKVAMIGSGMIGGTMGYLCALRELADVVLYDVVKGMPEGKALDLSHVTSVVD 61 >2HJR-A nrPDB Length = 328 Score = 32.3 bits (72), Expect = 0.41, Method: Compositional matrix adjust. Identities = 20/52 (38%), Positives = 29/52 (55%), Gaps = 3/52 (5%) Query: 152 KKLGIIGYGHIGTQLGIL--AESLGMYVYFYDIENKLPLGNATQVQHLSDLL 201 KK+ IIG G IG+ + +L + LG VY +DI +P G A + H L+ Sbjct: 15 KKISIIGAGQIGSTIALLLGQKDLGD-VYMFDIIEGVPQGKALDLNHCMALI 65 >3GKA-A nrPDB Length = 361 Score = 30.8 bits (68), Expect = 1.0, Method: Compositional matrix adjust. Identities = 23/74 (31%), Positives = 41/74 (55%), Gaps = 7/74 (9%) Query: 5 SLEKDKIKFLLVEGVHQKALESLRAAGYTNIEFH--KGALDDEQLKESIR---DAHFIGL 59 +LE D+I ++ ++ E+ RAAG+ +E H G L D+ L++S DA+ + Sbjct: 150 ALELDEIPGVVA--AFRRGAENARAAGFDGVEVHGANGYLLDQFLQDSANRRTDAYGGSI 207 Query: 60 RSRTHLTEDVINAA 73 +R L +V++AA Sbjct: 208 ENRARLLLEVVDAA 221 >5U8W-A nrPDB Length = 481 Score = 30.8 bits (68), Expect = 1.1, Method: Compositional matrix adjust. Identities = 17/40 (42%), Positives = 23/40 (57%) Query: 147 FEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKL 186 F+A KKLG+IG G IG +LG + LG V + +K Sbjct: 180 FQAVPKKLGVIGAGVIGLELGSVWARLGAEVTVLEALDKF 219 >5U1O-A nrPDB Length = 458 Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust. Identities = 28/126 (22%), Positives = 57/126 (45%), Gaps = 9/126 (7%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHV 211 K++ ++G G+I ++ + +LG + + + + PL + D + + +V + Sbjct: 175 KRVAVVGAGYIAVEIAGVLHALGTETHLF-VRKESPLRS-------FDPMIIDTLVEVME 226 Query: 212 PENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPA 271 E P+ KE+ GSL ++ G ++ L A+ +H A AI++ T A Sbjct: 227 AEGPTLHTHSVPKEVVKEADGSLTLHLENGESQNVDQLIWAIG-RHPATDAINLASTGVA 285 Query: 272 TNSDPF 277 TN + Sbjct: 286 TNEKGY 291 >3AK8-A nrPDB Length = 167 Score = 30.0 bits (66), Expect = 2.2, Method: Compositional matrix adjust. Identities = 20/60 (33%), Positives = 32/60 (53%), Gaps = 5/60 (8%) Query: 35 IEFHKGALDDEQLKESIRDAHFIGLRS-----RTHLTEDVINAAEKLVAIGCFCIGTNQV 89 I+F +L +Q ++R A+FI + RT LT+ + AE+ V +G +GT QV Sbjct: 38 IQFIDLSLITKQAHWNMRGANFIAVHEMLDGFRTALTDHLDTMAERAVQLGGVALGTTQV 97 >4PLW-A nrPDB Length = 326 Score = 29.6 bits (65), Expect = 2.2, Method: Compositional matrix adjust. Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 3/52 (5%) Query: 152 KKLGIIGYGHIGTQLG--ILAESLGMYVYFYDIENKLPLGNATQVQHLSDLL 201 KK+ +IG G+IG L I + LG V F DI +P G A + H S ++ Sbjct: 5 KKISLIGAGNIGGTLAHLIAQKELGDVVLF-DIVEGMPQGKALDISHSSPIM 55 >2R9Z-A nrPDB Length = 463 Score = 29.6 bits (65), Expect = 2.3, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 32/57 (56%), Gaps = 5/57 (8%) Query: 146 SFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKL-----PLGNATQVQHL 197 + + + K++ IIG G+IG +L L S G V +E++L PL +AT +++ Sbjct: 161 ALQQQPKRVAIIGAGYIGIELAGLLRSFGSEVTVVALEDRLLFQFDPLLSATLAENM 217 >4DYU-A nrPDB Length = 170 Score = 29.6 bits (65), Expect = 2.5, Method: Compositional matrix adjust. Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 11/85 (12%) Query: 35 IEFHKGALDDEQLKESIRDAHFIGLRS-----RTHLTEDVINAAEKLVAIGCFCIGTNQV 89 I+F +L +Q ++R A+F+ + RT LT+ + AE+ V +G +GT QV Sbjct: 41 IQFIDLSLITKQAHWNMRGANFVAVHEMLDGFRTALTDHLDTFAERAVQLGGVALGTAQV 100 Query: 90 DLDAAAKRGIPVFNAPFSNTRSVAE 114 D + P +N SV E Sbjct: 101 INDKTPLKSYP------TNIHSVQE 119 >6JCV-A nrPDB Length = 333 Score = 29.6 bits (65), Expect = 2.6, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 34/68 (50%), Gaps = 3/68 (4%) Query: 150 RGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENK---LPLGNATQVQHLSDLLNMSDV 206 +GK +G+IGYG+ G + G+ V ++++K L +V + + + SDV Sbjct: 14 KGKTIGVIGYGNQGRVQATIMRENGLNVIVGNVKDKYYELAKKEGFEVYEIDEAVRRSDV 73 Query: 207 VSLHVPEN 214 L +P+ Sbjct: 74 ALLLIPDE 81 >1Z9D-A nrPDB Length = 252 Score = 29.6 bits (65), Expect = 2.6, Method: Compositional matrix adjust. Identities = 39/169 (23%), Positives = 65/169 (38%), Gaps = 32/169 (18%) Query: 228 LMKPGSLLINASRGTVVDIP---ALCDALASKHLAGAAI-------DVFPTEPATNSDPF 277 L+K + +G +DIP A+ +A H++G I +++ EPA ++ Sbjct: 11 LIKLSGEALAGEKGVGIDIPTVQAIAKEIAEVHVSGVQIALVIGGGNLWRGEPAADAG-M 69 Query: 278 TSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDNGSTLSAVNFPEVSLPLHGG 337 ++ +L G+ A L +A L Y + +A+ V+ P G Sbjct: 70 DRVQADYTGML------GTVMNA-----LVMADSLQHYGVDTRVQTAIPMQNVAEPYIRG 118 Query: 338 RRLMHIHENRPGVLTALNKIFAEQGVNIAAQYLQTSAQMGYVVIDIEAD 386 R L H+ +NR V G I + Y T +IEAD Sbjct: 119 RALRHLEKNRIVVF----------GAGIGSPYFSTDTTAALRAAEIEAD 157 >1ONF-A nrPDB Length = 500 Score = 29.6 bits (65), Expect = 2.8, Method: Compositional matrix adjust. Identities = 14/47 (29%), Positives = 27/47 (57%), Gaps = 2/47 (4%) Query: 136 RGVWNKLAAGSFE--ARGKKLGIIGYGHIGTQLGILAESLGMYVYFY 180 +G+ N +++ F KK+GI+G G+I +L + + LG+ Y + Sbjct: 159 KGIENTISSDEFFNIKESKKIGIVGSGYIAVELINVIKRLGIDSYIF 205 >3RI6-A nrPDB Length = 430 Score = 29.3 bits (64), Expect = 3.6, Method: Compositional matrix adjust. Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 1/60 (1%) Query: 338 RRLMHIHENRPGVLTALNKIFAEQGVNIAAQYLQTSAQMGYVVIDIEADEDVAEKALQAM 397 RR +IH+N+ +L+ + I+A + L+ S M + + IE ED+ E LQA+ Sbjct: 371 RRATNIHDNKSLILSPYHVIYALNSHEERLK-LEISPAMMRLSVGIEEIEDLKEDILQAL 429 >1YB4-A nrPDB Length = 295 Score = 29.3 bits (64), Expect = 3.6, Method: Compositional matrix adjust. Identities = 19/73 (26%), Positives = 36/73 (49%), Gaps = 5/73 (6%) Query: 153 KLGIIGYGHIGTQLGILAESLGMYVYFYDI----ENKLPLGNATQVQHLSDLLNMSDVVS 208 KLG IG G +G+ + I G ++ I + L LG A V+ + +D++ Sbjct: 5 KLGFIGLGIMGSPMAINLARAGHQLHVTTIGPVADELLSLG-AVNVETARQVTEFADIIF 63 Query: 209 LHVPENPSTKNMM 221 + VP+ P ++++ Sbjct: 64 IMVPDTPQVEDVL 76 >5TR3-A nrPDB Length = 481 Score = 28.9 bits (63), Expect = 4.0, Method: Compositional matrix adjust. Identities = 15/31 (48%), Positives = 20/31 (64%) Query: 147 FEARGKKLGIIGYGHIGTQLGILAESLGMYV 177 F+A K+LG+IG G IG +LG + LG V Sbjct: 180 FQAVPKRLGVIGAGVIGLELGSVWARLGAEV 210 >4PLF-A nrPDB Length = 334 Score = 28.5 bits (62), Expect = 5.2, Method: Compositional matrix adjust. Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 4/59 (6%) Query: 144 AGSFEARGKKLGIIGYGHIGTQLGILA--ESLGMYVYFYDIENKLPLGNATQVQHLSDL 200 G+ R KK+ +IG G IG + L + LG V F D+ +P G A + H S + Sbjct: 2 TGTMTKR-KKISLIGSGMIGGTMAYLCAQKELGDVVLF-DVVKNMPQGKALDLSHSSSI 58 >6BZ0-A nrPDB Length = 480 Score = 28.5 bits (62), Expect = 5.4, Method: Compositional matrix adjust. Identities = 16/52 (30%), Positives = 28/52 (53%), Gaps = 1/52 (1%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYD-IENKLPLGNATQVQHLSDLLN 202 K+LG+IG G IG +LG + LG V ++ ++ LP+ + + +L Sbjct: 184 KRLGVIGAGVIGLELGSVWRRLGAEVVVFEAMDAFLPMADKALSKEYQKILT 235 >2FGC-A nrPDB Length = 193 Score = 28.5 bits (62), Expect = 5.7, Method: Compositional matrix adjust. Identities = 17/54 (31%), Positives = 31/54 (57%), Gaps = 3/54 (5%) Query: 341 MHIHENRPGVLTALNKIFAEQGVNIAAQYLQTSAQMGY--VVIDIEADEDVAEK 392 M +H N+PGV+ + +FA +G NI++ + S G +VI ++ D+ E+ Sbjct: 34 MLVH-NKPGVMRKVANLFARRGFNISSITVGESETPGLSRLVIMVKGDDKTIEQ 86 >3UP5-A nrPDB Length = 545 Score = 28.5 bits (62), Expect = 6.2, Method: Compositional matrix adjust. Identities = 23/72 (31%), Positives = 34/72 (47%), Gaps = 5/72 (6%) Query: 135 HRGVWNKLAAGS---FEARGKKLGIIGYGHIGTQ-LGILAESLG-MYVYFYDIENKLPLG 189 H W A G+ + GK++G+IG G G Q + I AE+ +YV+ PLG Sbjct: 166 HSSRWPTDAEGAPKGVDFTGKRVGVIGTGATGVQIIPIAAETAKELYVFQRTPNWCTPLG 225 Query: 190 NATQVQHLSDLL 201 N+ + D L Sbjct: 226 NSPMSKEKMDSL 237 >3SRE-A nrPDB Length = 355 Score = 28.1 bits (61), Expect = 7.8, Method: Compositional matrix adjust. Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 11/78 (14%) Query: 174 GMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGS 233 GM ++FYD EN P G ++V + D+L+ V++ EN + ++ ++ + G Sbjct: 288 GMRIFFYDAEN--PPG--SEVLRIQDILSEEPKVTVVYAENGT---VLQGSTVAAVYKGK 340 Query: 234 LLINASRGTVVDIPALCD 251 LLI GTV CD Sbjct: 341 LLI----GTVFHKALYCD 354 >6FSZ-II nrPDB Length = 301 Score = 27.7 bits (60), Expect = 8.4, Method: Compositional matrix adjust. Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 3/52 (5%) Query: 277 FTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAG---KLIKYSDNGSTLSAV 325 F P + L+ P G ++ ++ I V G KLI+Y NG TL A+ Sbjct: 14 FQFPEIAYPGKLICPQYGTENKDGEDIIFNYVPGPGTKLIQYEHNGRTLEAI 65 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2PA3-A nrPDB 554 e-158 3K5P-A nrPDB 508 e-144 5AOV-A nrPDB 363 e-101 2G76-A nrPDB 353 9e-98 6BII-A nrPDB 343 6e-95 1WWK-A nrPDB 322 2e-88 6IH4-A nrPDB 312 2e-85 4EBF-A nrPDB 312 2e-85 2DBZ-A nrPDB 311 3e-85 3KB6-A nrPDB 308 4e-84 2D0I-A nrPDB 306 1e-83 3FN4-A nrPDB 301 4e-82 3WR5-A nrPDB 294 7e-80 2WWR-A nrPDB 293 7e-80 5TX7-A nrPDB 292 2e-79 2GO1-A nrPDB 292 2e-79 1DXY-A nrPDB 286 1e-77 2EKL-A nrPDB 286 2e-77 4CUK-A nrPDB 285 2e-77 5Z1Z-A nrPDB 284 6e-77 2CUK-A nrPDB 282 2e-76 3DC2-A nrPDB 282 2e-76 6ABJ-A nrPDB 280 7e-76 3BA1-A nrPDB 279 1e-75 4ZGS-A nrPDB 278 3e-75 1GDH-A nrPDB 277 8e-75 1J49-A nrPDB 274 3e-74 2DLD-A nrPDB 269 2e-72 3JTM-A nrPDB 269 2e-72 4G2N-A nrPDB 269 2e-72 5UOG-A nrPDB 267 8e-72 4NFY-A nrPDB 267 8e-72 4XYG-A nrPDB 264 6e-71 6D4C-A nrPDB 264 7e-71 1HL3-A nrPDB 263 9e-71 2YQ5-A nrPDB 261 4e-70 5OFW-B nrPDB 261 4e-70 2OME-A nrPDB 261 5e-70 4LSW-A nrPDB 259 2e-69 4DGS-A nrPDB 259 2e-69 1XDW-A nrPDB 259 2e-69 6ABI-A nrPDB 256 1e-68 4S1V-D nrPDB 254 4e-68 4PRK-A nrPDB 254 7e-68 3WNV-A nrPDB 245 2e-65 3GG9-A nrPDB 245 3e-65 4XKJ-A nrPDB 241 3e-64 5DT9-A nrPDB 236 2e-62 3HG7-A nrPDB 233 9e-62 2W2L-A nrPDB 223 1e-58 3EVT-A nrPDB 215 2e-56 3OET-A nrPDB 215 3e-56 5MH6-A nrPDB 212 2e-55 4N18-A nrPDB 203 1e-52 5TSD-A nrPDB 200 1e-51 4WEQ-A nrPDB 198 5e-51 4XA8-A nrPDB 195 3e-50 5C5I-A nrPDB 191 5e-49 1QP8-A nrPDB 190 8e-49 3KBO-A nrPDB 189 2e-48 2O4C-A nrPDB 188 5e-48 4HY3-A nrPDB 182 2e-46 3GVX-A nrPDB 178 4e-45 Sequences not found previously or not previously below threshold: 5JXW-A nrPDB 57 2e-08 3H9U-A nrPDB 56 4e-08 6GBN-A nrPDB 54 1e-07 3G1U-A nrPDB 53 2e-07 2ZJ1-A nrPDB 51 7e-07 3D64-A nrPDB 50 1e-06 3OND-A nrPDB 50 2e-06 6JCV-A nrPDB 49 4e-06 3NJ4-A nrPDB 48 5e-06 6APH-A nrPDB 48 6e-06 3X2F-A nrPDB 48 7e-06 3N58-A nrPDB 48 1e-05 5M65-A nrPDB 46 2e-05 1V8B-A nrPDB 46 3e-05 5U5G-A nrPDB 45 4e-05 2VHY-A nrPDB 43 3e-04 5H82-A nrPDB 42 5e-04 4YPO-A nrPDB 41 0.001 2RIR-A nrPDB 40 0.001 6C55-A nrPDB 40 0.002 4KQW-A nrPDB 40 0.003 2GF2-A nrPDB 40 0.003 1X14-A nrPDB 39 0.003 2EEZ-A nrPDB 38 0.005 1V9L-A nrPDB 38 0.006 1VPD-A nrPDB 38 0.006 1GTM-A nrPDB 37 0.013 4TSK-A nrPDB 37 0.017 1NP3-A nrPDB 37 0.018 1GPJ-A nrPDB 36 0.020 3PVJ-A nrPDB 36 0.021 6ACF-A nrPDB 36 0.022 3AOE-E nrPDB 36 0.022 4XDZ-A nrPDB 36 0.023 5E4R-A nrPDB 36 0.024 4WJI-A nrPDB 36 0.025 2RCY-A nrPDB 36 0.026 1NPD-A nrPDB 36 0.026 3ABT-A nrPDB 36 0.030 2PV7-A nrPDB 36 0.030 1BVU-A nrPDB 36 0.032 1H2H-A nrPDB 36 0.036 5YEQ-A nrPDB 36 0.037 5L3D-A nrPDB 36 0.040 3VPX-A nrPDB 36 0.041 3TWO-A nrPDB 35 0.043 2CZC-A nrPDB 35 0.045 4PZE-A nrPDB 35 0.045 6F3O-A nrPDB 35 0.065 4D3F-A nrPDB 35 0.065 4XDY-A nrPDB 35 0.072 3DZB-A nrPDB 35 0.083 1A5Z-A nrPDB 35 0.085 3ULK-A nrPDB 35 0.092 4R16-A nrPDB 34 0.11 1CRW-G nrPDB 34 0.11 3G0O-A nrPDB 34 0.11 2F1K-A nrPDB 34 0.12 6JDK-A nrPDB 34 0.12 4OM8-A nrPDB 34 0.12 3MOG-A nrPDB 34 0.14 3F3S-A nrPDB 34 0.14 2CZG-A nrPDB 34 0.15 5Y8M-A nrPDB 34 0.15 5G6R-A nrPDB 34 0.16 6AON-A nrPDB 34 0.16 3B1F-A nrPDB 33 0.18 3AOE-A nrPDB 33 0.19 1YB4-A nrPDB 33 0.20 3CKY-A nrPDB 33 0.20 5XVH-A nrPDB 33 0.21 2R9Z-A nrPDB 33 0.21 2HK7-A nrPDB 33 0.21 2HMT-A nrPDB 33 0.22 6IQV-A nrPDB 33 0.22 5BUT-A nrPDB 33 0.23 1EZ1-A nrPDB 33 0.23 1CER-O nrPDB 33 0.23 4G65-A nrPDB 33 0.24 5U9P-A nrPDB 33 0.25 3FBG-A nrPDB 33 0.25 3ADO-A nrPDB 33 0.25 3F9I-A nrPDB 33 0.26 6HD1-C nrPDB 33 0.27 4J90-A nrPDB 33 0.28 3PII-A nrPDB 33 0.28 3UP5-A nrPDB 33 0.30 4IZO-A nrPDB 33 0.31 3UF0-A nrPDB 33 0.33 6ER9-A nrPDB 33 0.34 2BC1-A nrPDB 33 0.35 2UYY-A nrPDB 33 0.36 1BW9-B nrPDB 33 0.36 2HJR-A nrPDB 32 0.37 4DLL-A nrPDB 32 0.38 4RG3-A nrPDB 32 0.40 5T5Q-A nrPDB 32 0.41 5Y77-A nrPDB 32 0.42 4K28-A nrPDB 32 0.45 1CF2-P nrPDB 32 0.45 4XGI-A nrPDB 32 0.45 6BZ0-A nrPDB 32 0.48 3L8K-A nrPDB 32 0.49 1E3J-A nrPDB 32 0.51 4DLA-A nrPDB 32 0.51 3VTF-A nrPDB 32 0.54 3H9E-O nrPDB 32 0.55 6B4O-A nrPDB 32 0.59 1EUZ-A nrPDB 31 0.63 1VC2-A nrPDB 31 0.63 4DYD-A nrPDB 31 0.64 4E21-A nrPDB 31 0.66 3OJO-A nrPDB 31 0.72 2Z04-A nrPDB 31 0.72 4JJI-A nrPDB 31 0.75 3MJ4-A nrPDB 31 0.79 1PJB-A nrPDB 31 0.81 4YRY-B nrPDB 31 0.83 5C7I-O nrPDB 31 0.87 6N7L-A nrPDB 31 0.88 6DHM-A nrPDB 31 0.95 4DIO-A nrPDB 31 1.0 3MWB-A nrPDB 31 1.0 1BG6-A nrPDB 31 1.0 4GBJ-A nrPDB 31 1.1 3WTC-A nrPDB 31 1.1 6DU7-A nrPDB 31 1.1 2X41-A nrPDB 31 1.1 1ZCJ-A nrPDB 31 1.3 1L1F-A nrPDB 30 1.5 3PEF-A nrPDB 30 1.6 1DOH-A nrPDB 30 1.6 6IHE-A nrPDB 30 1.6 2FGC-A nrPDB 30 1.6 3RWB-A nrPDB 30 1.7 3ZWA-A nrPDB 30 1.7 3EZY-A nrPDB 30 1.7 4OH1-A nrPDB 30 1.8 1JAY-A nrPDB 30 1.8 1HYH-A nrPDB 30 1.9 5T57-A nrPDB 30 2.0 4DBZ-A nrPDB 30 2.0 3K8Z-A nrPDB 30 2.0 1GEU-A nrPDB 30 2.0 1AE1-A nrPDB 30 2.0 5J9G-A nrPDB 30 2.1 2DC1-A nrPDB 30 2.1 4J0E-A nrPDB 30 2.1 4B3J-A nrPDB 30 2.2 4A7P-A nrPDB 30 2.2 3D3W-A nrPDB 30 2.3 5U8W-A nrPDB 30 2.3 5U1O-A nrPDB 30 2.4 3E5R-O nrPDB 30 2.4 5TR3-A nrPDB 30 2.4 3VB0-A nrPDB 30 3.0 5YX3-A nrPDB 30 3.1 2VYN-D nrPDB 29 3.1 3DOJ-A nrPDB 29 3.2 3VZS-A nrPDB 29 3.3 3ZHB-A nrPDB 29 3.4 3NDC-A nrPDB 29 3.4 2EW8-A nrPDB 29 3.4 1VSU-A nrPDB 29 3.6 3GG2-A nrPDB 29 3.8 3LK7-A nrPDB 29 3.8 4AP1-A nrPDB 29 3.8 2O3A-A nrPDB 29 3.9 3O0H-A nrPDB 29 4.1 6HRD-A nrPDB 29 4.1 4Z0H-O nrPDB 29 4.2 5VDN-A nrPDB 29 4.2 3IHM-A nrPDB 29 4.3 5VT6-A nrPDB 29 4.4 3PDU-A nrPDB 29 4.6 4OQY-A nrPDB 29 4.7 2DQ4-A nrPDB 29 4.7 2NVK-X nrPDB 28 5.3 2GRA-A nrPDB 28 5.4 5TPR-A nrPDB 28 5.5 3TR8-A nrPDB 28 5.5 4RZI-B nrPDB 28 5.5 3IC9-A nrPDB 28 5.5 2B4T-O nrPDB 28 5.5 5ZZ6-A nrPDB 28 5.7 3UVE-A nrPDB 28 6.0 5A9T-A nrPDB 28 6.5 5VMT-A nrPDB 28 6.9 3L6D-A nrPDB 28 6.9 3IHG-A nrPDB 28 6.9 1LLU-A nrPDB 28 6.9 2VG4-A nrPDB 28 7.4 5NC8-A nrPDB 28 7.7 5B37-A nrPDB 28 7.9 2HTM-A nrPDB 28 8.1 4A5O-A nrPDB 28 9.0 6F8L-G nrPDB 28 9.1 3GRP-A nrPDB 28 9.4 3DWF-A nrPDB 28 9.4 4CQL-A nrPDB 28 9.5 >2PA3-A nrPDB Length = 410 Score = 554 bits (1428), Expect = e-158, Method: Composition-based stats. Identities = 405/410 (98%), Positives = 405/410 (98%) Query: 1 MAKVSLEKDKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLR 60 MAKVSLEKDKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLR Sbjct: 1 MAKVSLEKDKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLR 60 Query: 61 SRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGEL 120 SRTHLTEDVINAAEKLVAIG F IGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGEL Sbjct: 61 SRTHLTEDVINAAEKLVAIGAFAIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGEL 120 Query: 121 LLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFY 180 LLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFY Sbjct: 121 LLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFY 180 Query: 181 DIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASR 240 DIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASR Sbjct: 181 DIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASR 240 Query: 241 GTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEA 300 GTVVDIPAL DALASKHLAGAAIDVFPTEPATNSDPFTSPL EFDNVLLTPHIGGSTQEA Sbjct: 241 GTVVDIPALADALASKHLAGAAIDVFPTEPATNSDPFTSPLAEFDNVLLTPHIGGSTQEA 300 Query: 301 QENIGLEVAGKLIKYSDNGSTLSAVNFPEVSLPLHGGRRLMHIHENRPGVLTALNKIFAE 360 QENIGLEVAGKLIKYSDNGSTLSAVNFPEVSLPLH GRRLMHIHENRPGVLTALNKIFAE Sbjct: 301 QENIGLEVAGKLIKYSDNGSTLSAVNFPEVSLPLHVGRRLMHIHENRPGVLTALNKIFAE 360 Query: 361 QGVNIAAQYLQTSAQMGYVVIDIEADEDVAEKALQAMKAIPGTIRARLLY 410 QGVNIAAQYLQTSAQMGYVVIDIEADEDVAEKALQAMKAIPGTIRARLLY Sbjct: 361 QGVNIAAQYLQTSAQMGYVVIDIEADEDVAEKALQAMKAIPGTIRARLLY 410 >3K5P-A nrPDB Length = 416 Score = 508 bits (1308), Expect = e-144, Method: Composition-based stats. Identities = 224/409 (54%), Positives = 297/409 (72%), Gaps = 1/409 (0%) Query: 3 KVSLEKDKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSR 62 ++SL +D+I LL+EG+ Q A+E +++GYTN+ ALD L ++I AH IG+RSR Sbjct: 8 RLSLSRDRINVLLLEGISQTAVEYFKSSGYTNVTHLPKALDKADLIKAISSAHIIGIRSR 67 Query: 63 THLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLL 122 T LTE++ AA +L+A+GCF +GTNQV+L AA KRGIPVFNAPFSNTRSVAELVIGE+++ Sbjct: 68 TQLTEEIFAAANRLIAVGCFSVGTNQVELKAARKRGIPVFNAPFSNTRSVAELVIGEIIM 127 Query: 123 LLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDI 182 L+R + + AH G W K A GS E RGK LGI+GYG+IG+Q+G LAESLGM V +YD Sbjct: 128 LMRRIFPRSVSAHAGGWEKTAIGSREVRGKTLGIVGYGNIGSQVGNLAESLGMTVRYYDT 187 Query: 183 ENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGT 242 +KL GN L +LL SDVVSLHVP + ST ++ ++ MK G+ LIN +RG+ Sbjct: 188 SDKLQYGNVKPAASLDELLKTSDVVSLHVPSSKSTSKLITEAKLRKMKKGAFLINNARGS 247 Query: 243 VVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQE 302 VD+ AL L HLAGAAIDVFP EPA+N + F++PL +NV+LTPHIGGST+EAQE Sbjct: 248 DVDLEALAKVLQEGHLAGAAIDVFPVEPASNGERFSTPLQGLENVILTPHIGGSTEEAQE 307 Query: 303 NIGLEVAGKLIKYSDNGSTLSAVNFPEVSLPLH-GGRRLMHIHENRPGVLTALNKIFAEQ 361 IG EV KL++YSD GST+ AVNFP+V LP G R MH+HENRPG+L +L +F+ Sbjct: 308 RIGTEVTRKLVEYSDVGSTVGAVNFPQVQLPPRPTGTRFMHVHENRPGILNSLMNVFSHH 367 Query: 362 GVNIAAQYLQTSAQMGYVVIDIEADEDVAEKALQAMKAIPGTIRARLLY 410 +NIA+Q+LQT ++GY+V++ + + ++ LQ ++ IPGTIRARLLY Sbjct: 368 HINIASQFLQTDGEVGYLVMEADGVGEASDAVLQEIREIPGTIRARLLY 416 >5AOV-A nrPDB Length = 336 Score = 363 bits (932), Expect = e-101, Method: Composition-based stats. Identities = 94/326 (28%), Positives = 149/326 (45%), Gaps = 14/326 (4%) Query: 10 KIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDV 69 K K + + + + L + + + E+L E ++D + + ++V Sbjct: 2 KPKVFITRAIPENGINMLEEEFEVEVWEEEREIPREKLLEKVKDVDALVTMLSERIDQEV 61 Query: 70 INAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPE 129 A +L + + +G + +D++ A +RGI V N P T + A+ LL R V + Sbjct: 62 FENAPRLRIVANYAVGYDNIDVEEATRRGIYVTNTPDVLTNATADHAFALLLATARHVVK 121 Query: 130 ANAKAHRGVWN-------KLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDI 182 + G W +E GK +GI+G+G IG + A+ M + +Y Sbjct: 122 GDKFVRSGEWKRKGIAWHPKWFLGYELYGKTIGIVGFGRIGQAIARRAKGFNMRILYYSR 181 Query: 183 ENKLPLGNA--TQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASR 240 K + + L ++L SD V L VP T M+ + + LMKP ++L+N +R Sbjct: 182 TRKSQAEKELGAEYRPLEEVLKESDFVILAVPLTKETMYMINEERLKLMKPTAILVNIAR 241 Query: 241 GTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEA 300 G VVD AL AL +AGA +DVF EP N + L DNV+LTPHIG +T EA Sbjct: 242 GKVVDTKALIKALKEGWIAGAGLDVFEEEPYYNEE-----LFSLDNVVLTPHIGSATFEA 296 Query: 301 QENIGLEVAGKLIKYSDNGSTLSAVN 326 +E + VA LI + + VN Sbjct: 297 REAMAELVARNLIAFKRGEIPPTLVN 322 >2G76-A nrPDB Length = 335 Score = 353 bits (906), Expect = 9e-98, Method: Composition-based stats. Identities = 111/316 (35%), Positives = 164/316 (51%), Gaps = 10/316 (3%) Query: 12 KFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVIN 71 K L+ + + + L+ G +E K L E+L ++D + +RS T +T DVIN Sbjct: 28 KVLISDSLDPCCRKILQDGGLQVVE--KQNLSKEELIAELQDCEGLIVRSATKVTADVIN 85 Query: 72 AAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEAN 131 AAEKL +G G + VDL+AA ++GI V N P N+ S AEL G ++ L R +P+A Sbjct: 86 AAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQAT 145 Query: 132 AKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYD--IENKLPLG 189 A G W + E GK LGI+G G IG ++ +S GM YD I ++ Sbjct: 146 ASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSAS 205 Query: 190 NATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPAL 249 Q L ++ + D +++H P PST ++ + K G ++N +RG +VD AL Sbjct: 206 FGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGAL 265 Query: 250 CDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVA 309 AL S AGAA+DVF EP P L + +NV+ PH+G ST+EAQ G E+A Sbjct: 266 LRALQSGQCAGAALDVFTEEP-----PRDRALVDHENVISCPHLGASTKEAQSRCGEEIA 320 Query: 310 GKLIKYSDNGSTLSAV 325 + + G +L+ V Sbjct: 321 VQFVDMV-KGKSLTGV 335 >6BII-A nrPDB Length = 333 Score = 343 bits (881), Expect = 6e-95, Method: Composition-based stats. Identities = 98/326 (30%), Positives = 155/326 (47%), Gaps = 14/326 (4%) Query: 10 KIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDV 69 K K L+ + + +E LR + H+ + E L E ++D + + +V Sbjct: 2 KPKVLITRAIPENGIELLREHFEVEVWEHEHEIPREVLLEKVKDVDALVTMLSEKIDREV 61 Query: 70 INAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPE 129 +AA +L + + +G + +D++ A KRGI V N P T + A+L LL R V + Sbjct: 62 FDAAPRLRIVANYAVGYDNIDIEEATKRGIYVTNTPDVLTDATADLAWALLLAAARHVVK 121 Query: 130 ANAKAHRGVWNKLAAG-------SFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDI 182 + G W + ++ GK +GI+G+G IG + A+ GM + + Sbjct: 122 GDKFVRSGEWKRRGIAWHPKMFLGYDVYGKTIGIVGFGRIGQAIAKRAKGFGMRILYTAR 181 Query: 183 ENKLPLGNA--TQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASR 240 K + + L +LL SD V L VP T +M+ + + LMKP ++L+N +R Sbjct: 182 SRKPEAEKELGAEFKPLEELLRESDFVVLAVPLTKETYHMINEERLRLMKPTAVLVNVAR 241 Query: 241 GTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEA 300 G VVD AL AL +A A +DVF EP + + L DNV+LTPHIG +T A Sbjct: 242 GKVVDTKALIRALKEGWIAAAGLDVFEEEPYYDEE-----LFALDNVVLTPHIGSATFGA 296 Query: 301 QENIGLEVAGKLIKYSDNGSTLSAVN 326 +E + VA LI + + + VN Sbjct: 297 REGMAELVAKNLIAFKNGEVPPTLVN 322 >1WWK-A nrPDB Length = 307 Score = 322 bits (825), Expect = 2e-88, Method: Composition-based stats. Identities = 126/311 (40%), Positives = 183/311 (58%), Gaps = 8/311 (2%) Query: 10 KIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDV 69 ++K L+ +H+KA++ L+ AG I ++ D+++L E ++D I +RS+ +T V Sbjct: 3 RMKVLVAAPLHEKAIQVLKDAGLEVI--YEEYPDEDRLVELVKDVEAIIVRSKPKVTRRV 60 Query: 70 INAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPE 129 I +A KL I +G + +D++AA ++GI V NAP +++RSVAEL +G + + R + Sbjct: 61 IESAPKLKVIARAGVGLDNIDVEAAKEKGIEVVNAPAASSRSVAELAVGLMFSVARKIAF 120 Query: 130 ANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLG 189 A+ K GVW K A E GK +GIIG+G IG Q+ +A +LGM + YD Sbjct: 121 ADRKMREGVWAKKEAMGIELEGKTIGIIGFGRIGYQVAKIANALGMNILLYDPYPNEERA 180 Query: 190 NAT--QVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIP 247 + L LL SDVV++HVP ST +++ + + LMK ++LIN SRG VVD Sbjct: 181 KEVNGKFVDLETLLKESDVVTIHVPLVESTYHLINEERLKLMKKTAILINTSRGPVVDTN 240 Query: 248 ALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLE 307 AL AL +AGA +DVF EP P PL +FDNV+LTPHIG ST EAQE G+E Sbjct: 241 ALVKALKEGWIAGAGLDVFEEEPL----PKDHPLTKFDNVVLTPHIGASTVEAQERAGVE 296 Query: 308 VAGKLIKYSDN 318 VA K++K Sbjct: 297 VAEKVVKILKG 307 >6IH4-A nrPDB Length = 338 Score = 312 bits (799), Expect = 2e-85, Method: Composition-based stats. Identities = 94/328 (28%), Positives = 138/328 (42%), Gaps = 9/328 (2%) Query: 10 KIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDV 69 K K +L VH + +E L A+ + L ++ +DA + + Sbjct: 2 KPKVVLTHWVHPEIIELLSASADVIPNTTRETLPRSEVIARAKDADALMAFMPDSIDSAF 61 Query: 70 INAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPE 129 + KL IG G + D++A + G+ + P T AEL IG LL L R + E Sbjct: 62 LEECPKLRVIGAALKGYDNFDVNACTRHGVWLTIVPDLLTIPTAELTIGLLLGLTRHMLE 121 Query: 130 ANAKAHRGVWNKL--AAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIEN--- 184 + + G + GK LGI G G +G + M + + D Sbjct: 122 GDRQIRSGHFQGWRPTLYGSGLTGKTLGIRGMGAVGRAIAQRLAGFEMNLLYCDEIPLNA 181 Query: 185 KLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVV 244 + Q L +LL D V VP T +++ A ++ MK GS LINA RG+VV Sbjct: 182 EQEKAWHVQRVTLDELLEKCDYVVPMVPMAAETLHLIDATALAKMKTGSYLINACRGSVV 241 Query: 245 DIPALCDALASKHLAGAAIDVFPTEPATNSD-PFTSPLCEFDN---VLLTPHIGGSTQEA 300 D A+ ALAS LAG A DVF E +D P P DN TPH+G + +E Sbjct: 242 DENAVIAALASGKLAGYAADVFEMEEWIRADRPQAIPKALLDNTAQTFFTPHLGSAVKEV 301 Query: 301 QENIGLEVAGKLIKYSDNGSTLSAVNFP 328 + I + A +I+ + A+N P Sbjct: 302 RLEIERQAAMNIIQALAGEKPMGAINQP 329 >4EBF-A nrPDB Length = 334 Score = 312 bits (799), Expect = 2e-85, Method: Composition-based stats. Identities = 87/326 (26%), Positives = 140/326 (42%), Gaps = 12/326 (3%) Query: 11 IKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVI 70 K ++ VH++ L+ L L E++ RDA + + D + Sbjct: 4 PKLVITHRVHEEILQLLAPHCELITNQTDSTLTREEILRRCRDAQAMMAFMPDRVDADFL 63 Query: 71 NAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEA 130 A +L IGC G + D+DA RG+ + P T AEL IG + L R + A Sbjct: 64 QACPELRVIGCALKGFDNFDVDACTARGVWLTFVPDLLTVPTAELAIGLAVGLGRHLRAA 123 Query: 131 NAKAHRGVWNKLA--AGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFY-----DIE 183 +A G + +G +G G IG + + G + ++ D + Sbjct: 124 DAFVRSGQFRGWQPRFYGTGLDNATVGFLGMGAIGLAMADRLQGWGATLQYHAAKALDTQ 183 Query: 184 NKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTV 243 + LG + S+L SD + L +P N T +++ A+ ++L++PG+LL+N RG+V Sbjct: 184 TEQRLG--LRQVACSELFASSDFILLALPLNADTLHLVNAELLALVRPGALLVNPCRGSV 241 Query: 244 VDIPALCDALASKHLAGAAIDVFPTEPATNSDP---FTSPLCEFDNVLLTPHIGGSTQEA 300 VD A+ AL L G A DVF E +D L N L TPHIG + + Sbjct: 242 VDEAAVLAALERGQLGGYAADVFEMEDWARADRPQQIDPALLAHPNTLFTPHIGSAVRAV 301 Query: 301 QENIGLEVAGKLIKYSDNGSTLSAVN 326 + I A +++ ++AVN Sbjct: 302 RLEIERCAAQNILQALAGERPINAVN 327 >2DBZ-A nrPDB Length = 334 Score = 311 bits (797), Expect = 3e-85, Method: Composition-based stats. Identities = 95/326 (29%), Positives = 151/326 (46%), Gaps = 14/326 (4%) Query: 10 KIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDV 69 K K + + + ++ L + + + E L + +++ + + ++V Sbjct: 2 KPKVFITREIPEVGIKMLEDEFEVEVWGDEKEIPREILLKKVKEVDALVTMLSERIDKEV 61 Query: 70 INAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPE 129 A KL + + +G + +D++ A KRGI V N P T + A+L LL R V + Sbjct: 62 FENAPKLRIVANYAVGYDNIDIEEATKRGIYVTNTPDVLTDATADLAFALLLATARHVVK 121 Query: 130 ANAKAHRGVWNKLA-------AGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDI 182 + G W K ++ GK +GIIG G IG + A+ M + +Y Sbjct: 122 GDRFVRSGEWKKRGVAWHPKWFLGYDVYGKTIGIIGLGRIGQAIAKRAKGFNMRILYYSR 181 Query: 183 ENKLPLGNA--TQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASR 240 K + + + L DLL SD V L VP T +++ + + LMK ++LIN +R Sbjct: 182 TRKEEVERELNAEFKPLEDLLRESDFVVLAVPLTRETYHLINEERLKLMKKTAILINIAR 241 Query: 241 GTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEA 300 G VVD AL AL +AGA +DVF EP N + L + DNV+LTPHIG ++ A Sbjct: 242 GKVVDTNALVKALKEGWIAGAGLDVFEEEPYYNEE-----LFKLDNVVLTPHIGSASFGA 296 Query: 301 QENIGLEVAGKLIKYSDNGSTLSAVN 326 +E + VA LI + + VN Sbjct: 297 REGMAELVAKNLIAFKRGEIPPTLVN 322 >3KB6-A nrPDB Length = 334 Score = 308 bits (788), Expect = 4e-84, Method: Composition-based stats. Identities = 90/310 (29%), Positives = 144/310 (46%), Gaps = 24/310 (7%) Query: 33 TNIEFHKGALDDEQL-----------KESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGC 81 ++ F++ AL D L + ++ A I + LTE++++ +L I Sbjct: 11 EDVPFYQEALKDLSLKIYTTDVSKVPENELKKAELISVFVYDKLTEELLSKMPRLKLIHT 70 Query: 82 FCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNK 141 +G + +DLD K+GI V + P + SVAE +L L++ + + + +++ Sbjct: 71 RSVGFDHIDLDYCKKKGILVTHIPAYSPESVAEHTFAMILTLVKRLKRIEDRVKKLNFSQ 130 Query: 142 LAAG-SFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPL-GNATQVQHLSD 199 + + E LG+IG G IG+++ + + GM V YD+ + L L + Sbjct: 131 DSEILARELNRLTLGVIGTGRIGSRVAMYGLAFGMKVLCYDVVKREDLKEKGCVYTSLDE 190 Query: 200 LLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLA 259 LL SDV+SLHVP T +M+ + ISLMK G LIN +RG VVD AL A + Sbjct: 191 LLKESDVISLHVPYTKETHHMINEERISLMKDGVYLINTARGKVVDTDALYRAYQRGKFS 250 Query: 260 GAAIDVFPTE-----------PATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEV 308 G +DVF E AT+ + L DNV++TPHI T ++ E I E Sbjct: 251 GLGLDVFEDEEILILKKYTEGKATDKNLKILELACKDNVIITPHIAYYTDKSLERIREET 310 Query: 309 AGKLIKYSDN 318 + + Sbjct: 311 VKVVKAFVKG 320 >2D0I-A nrPDB Length = 333 Score = 306 bits (784), Expect = 1e-83, Method: Composition-based stats. Identities = 91/333 (27%), Positives = 148/333 (44%), Gaps = 16/333 (4%) Query: 10 KIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDV 69 + K ++ + ++ALE L+ I + E+LK I I + T +T +V Sbjct: 2 RPKVGVLLKMKREALEELKKYADVEIILYPSG---EELKGVIGRFDGIIVSPTTKITREV 58 Query: 70 INAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPE 129 + AE+L I C G + +DL+ A KRGI V + +VAE +G ++ L+R + Sbjct: 59 LENAERLKVISCHSAGYDNIDLEEATKRGIYVTKVSGLLSEAVAEFTVGLIINLMRKIHY 118 Query: 130 ANAKAHRGVWN-----KLAAGSFE-ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIE 183 A+ RG W E GKK+GI+G G IG + G+ +Y++ Sbjct: 119 ADKFIRRGEWESHAKIWTGFKRIESLYGKKVGILGMGAIGKAIARRLIPFGVKLYYWSRH 178 Query: 184 NKLPLGNA--TQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRG 241 K+ + + + +LL SD+V L +P T +++ + + + G L+N RG Sbjct: 179 RKVNVEKELKARYMDIDELLEKSDIVILALPLTRDTYHIINEERVKKL-EGKYLVNIGRG 237 Query: 242 TVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQ 301 +VD A+ +A+ L G A DVF EP + F +LTPH G EAQ Sbjct: 238 ALVDEKAVTEAIKQGKLKGYATDVFEKEPVREHELFKYEWE----TVLTPHYAGLALEAQ 293 Query: 302 ENIGLEVAGKLIKYSDNGSTLSAVNFPEVSLPL 334 E++G L+K VN + + Sbjct: 294 EDVGFRAVENLLKVLRGEVPEDLVNKEVLEVRP 326 >3FN4-A nrPDB Length = 401 Score = 301 bits (771), Expect = 4e-82, Method: Composition-based stats. Identities = 88/305 (28%), Positives = 143/305 (46%), Gaps = 14/305 (4%) Query: 23 ALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRS--RTHLTEDVINAAEKLVAIG 80 + L + G+ + D +L++ + DA I + +LT + I A KL Sbjct: 59 LRKYLESQGHELVVTSSKDGPDSELEKHLHDAEVIISQPFWPAYLTAERIAKAPKLKLAL 118 Query: 81 CFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWN 140 IG++ VDL AA I V + N+ SVAE V+ +L L+R ++ A G WN Sbjct: 119 TAGIGSDHVDLQAAIDNNITVAEVTYCNSNSVAEHVVMMVLGLVRNYIPSHDWARNGGWN 178 Query: 141 --KLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNA-----TQ 193 A S++ G +G + G IG ++ L M++++ D ++LP T Sbjct: 179 IADCVARSYDVEGMHVGTVAAGRIGLRVLRLLAPFDMHLHYTDR-HRLPEAVEKELNLTW 237 Query: 194 VQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDAL 253 D+ DVV+L+ P +P T++M+ + + L K G+ L+N +RG + D A+ AL Sbjct: 238 HATREDMYGACDVVTLNCPLHPETEHMINDETLKLFKRGAYLVNTARGKLCDRDAIVRAL 297 Query: 254 ASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLI 313 S LAG A DV+ +PA N P+ + + +TPHI G++ AQ L Sbjct: 298 ESGRLAGYAGDVWFPQPAPNDHPWRT----MPHNGMTPHISGTSLSAQTRYAAGTREILE 353 Query: 314 KYSDN 318 Y + Sbjct: 354 CYFEG 358 >3WR5-A nrPDB Length = 406 Score = 294 bits (752), Expect = 7e-80, Method: Composition-based stats. Identities = 82/309 (26%), Positives = 143/309 (46%), Gaps = 15/309 (4%) Query: 23 ALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRS--RTHLTEDVINAAEKLVAIG 80 + L A G+T + D ++ + DA + + +LT + I A+ L Sbjct: 65 LRKYLEANGHTFVVTSDKDGPDSVFEKELVDADVVISQPFWPAYLTPERIAKAKNLKLAL 124 Query: 81 CFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWN 140 IG++ VDL +A RGI V + N+ SVAE V+ +L L+R ++ A +G WN Sbjct: 125 TAGIGSDHVDLQSAIDRGITVAEVTYCNSISVAEHVVMMILGLVRNYIPSHDWARKGGWN 184 Query: 141 --KLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNA-----TQ 193 S++ G +G + G IG + + +++ D ++LP Sbjct: 185 IADCVEHSYDLEGMTVGSVAAGRIGLAVLRRLAPFDVKLHYTDR-HRLPEAVEKELGLVW 243 Query: 194 VQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDAL 253 D+ DVV+L+VP +P T++M+ + + L K G+ ++N +RG + D A+ A+ Sbjct: 244 HDTREDMYPHCDVVTLNVPLHPETEHMINDETLKLFKRGAYIVNTARGKLADRDAIVRAI 303 Query: 254 ASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLI 313 S LAG A DV+ +PA P+ + E +TPHI G++ AQ +++ Sbjct: 304 ESGQLAGYAGDVWFPQPAPKDHPWRTMKWE----GMTPHISGTSLSAQARYAAGT-REIL 358 Query: 314 KYSDNGSTL 322 + G + Sbjct: 359 ECFFEGRPI 367 >2WWR-A nrPDB Length = 330 Score = 293 bits (751), Expect = 7e-80, Method: Composition-based stats. Identities = 83/326 (25%), Positives = 132/326 (40%), Gaps = 13/326 (3%) Query: 11 IKFLLVEGVHQKALESLRAAGYTNIEF--HKGALDDEQLKESIRDAHFIGLRSRTHLTED 68 +K + + + +L A +E + ++L+ + AH + H+ + Sbjct: 9 MKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKR 68 Query: 69 VINAA-EKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGV 127 +++AA L I +G + + LD KRGI V P T + AEL + LL R + Sbjct: 69 ILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRL 128 Query: 128 PEANAKAHRGVW---NKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIEN 184 PEA + G W L + +GIIG G IG + + G+ + Y Sbjct: 129 PEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQ 188 Query: 185 KLPLGNA---TQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRG 241 P A + +L SD + + P+T+ + MK ++ IN SRG Sbjct: 189 PRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRG 248 Query: 242 TVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQ 301 VV+ L ALAS +A A +DV EP P PL N ++ PHIG +T + Sbjct: 249 DVVNQDDLYQALASGKIAAAGLDVTSPEPL----PTNHPLLTLKNCVILPHIGSATHRTR 304 Query: 302 ENIGLEVAGKLIKYSDNGSTLSAVNF 327 + L A L+ S + Sbjct: 305 NTMSLLAANNLLAGLRGEPMPSELKL 330 >5TX7-A nrPDB Length = 327 Score = 292 bits (748), Expect = 2e-79, Method: Composition-based stats. Identities = 93/313 (29%), Positives = 150/313 (47%), Gaps = 16/313 (5%) Query: 27 LRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCIGT 86 + G + H +++ E AH + + L + A L + G Sbjct: 22 IEELGELVV--HPRT-PSDKIIERAAGAHVVLTN-KVPLDMSALQALPGLRFVSVLATGY 77 Query: 87 NQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGS 146 ++VD+ AA GIPV N P T SVA+ V LL L R + + G W + Sbjct: 78 DKVDVAAAGVLGIPVSNVPGYGTDSVAQHVFALLLELCRRTALHDHRIRAGAWTQSPDWC 137 Query: 147 F------EARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKL-PLGNATQVQHLSD 199 F E GK +GI+G+G+ G ++G +A +LGM V Y ++ P + L + Sbjct: 138 FWDSTQEELTGKTMGIVGFGNTGRRVGRIANALGMNVIAYAPRSRFDPDYRPFEHVGLDE 197 Query: 200 LLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLA 259 L +DVVSLH P P T+ ++ A+ ++ M+PGS LIN +RG ++D A+ +AL S LA Sbjct: 198 LFTSADVVSLHCPLTPETEGLVDARRLASMRPGSYLINTARGPLLDERAVAEALDSGRLA 257 Query: 260 GAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDNG 319 GA +DV EP + PL N L+TPH+ +++ A+ + A + + + G Sbjct: 258 GAGLDVLSQEPPAADN----PLLSAKNCLITPHLAWASRTARRTLMDSTAANIRSFIE-G 312 Query: 320 STLSAVNFPEVSL 332 + ++ VN + Sbjct: 313 TPVNVVNAAHLRT 325 >2GO1-A nrPDB Length = 401 Score = 292 bits (747), Expect = 2e-79, Method: Composition-based stats. Identities = 79/309 (25%), Positives = 141/309 (45%), Gaps = 15/309 (4%) Query: 23 ALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRS--RTHLTEDVINAAEKLVAIG 80 + L + G+T + D + + DA + + +LT + I A+ L Sbjct: 60 LRKYLESNGHTLVVTSDKDGPDSVFERELVDADVVISQPFWPAYLTPERIAKAKNLKLAL 119 Query: 81 CFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWN 140 IG++ VDL +A R + V + N+ SVAE V+ +L L+R ++ A +G WN Sbjct: 120 TAGIGSDHVDLQSAIDRNVTVAEVTYCNSISVAEHVVMMILSLVRNYLPSHEWARKGGWN 179 Query: 141 --KLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNA-----TQ 193 + +++ +G + G IG + +++++ D ++LP T Sbjct: 180 IADCVSHAYDLEAMHVGTVAAGRIGLAVLRRLAPFDVHLHYTDR-HRLPESVEKELNLTW 238 Query: 194 VQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDAL 253 D+ + DVV+L+ P +P T++M+ + + L K G+ ++N +RG + D A+ AL Sbjct: 239 HATREDMYPVCDVVTLNCPLHPETEHMINDETLKLFKRGAYIVNTARGKLCDRDAVARAL 298 Query: 254 ASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLI 313 S LAG A DV+ +PA P P +TPHI G+T AQ +++ Sbjct: 299 ESGRLAGYAGDVWFPQPA----PKDHPWRTMPYNGMTPHISGTTLTAQARYAAGT-REIL 353 Query: 314 KYSDNGSTL 322 + G + Sbjct: 354 ECFFEGRPI 362 >1DXY-A nrPDB Length = 333 Score = 286 bits (731), Expect = 1e-77, Method: Composition-based stats. Identities = 82/307 (26%), Positives = 132/307 (42%), Gaps = 13/307 (4%) Query: 34 NIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVINA--AEKLVAIGCFCIGTNQVDL 91 +E+H LD+ ++ + + I T V A + + +GT+ +D+ Sbjct: 26 TLEYHTEFLDENTVEWA-KGFDGINSLQTTPYAAGVFEKMHAYGIKFLTIRNVGTDNIDM 84 Query: 92 DAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLA-AGSFEAR 150 A + GI + N P + ++AE + + L LLR + + A+ G + K E Sbjct: 85 TAMKQYGIRLSNVPAYSPAAIAEFALTDTLYLLRNMGKVQAQLQAGDYEKAGTFIGKELG 144 Query: 151 GKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLH 210 + +G++G GHIG L + G V YD L DL SDV+ LH Sbjct: 145 QQTVGVMGTGHIGQVAIKLFKGFGAKVIAYDPYPMKGDHPDFDYVSLEDLFKQSDVIDLH 204 Query: 211 VPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEP 270 VP +++ +LMKPG+++IN +R ++D A+ L S LAG ID + E Sbjct: 205 VPGIEQNTHIINEAAFNLMKPGAIVINTARPNLIDTQAMLSNLKSGKLAGVGIDTYEYET 264 Query: 271 ---------ATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDNGST 321 + DP L NV+L+PHI T+ A N+ L+ + G T Sbjct: 265 EDLLNLAKHGSFKDPLWDELLGMPNVVLSPHIAYYTETAVHNMVYFSLQHLVDFLTKGET 324 Query: 322 LSAVNFP 328 + V P Sbjct: 325 STEVTGP 331 >2EKL-A nrPDB Length = 313 Score = 286 bits (731), Expect = 2e-77, Method: Composition-based stats. Identities = 98/309 (31%), Positives = 160/309 (51%), Gaps = 8/309 (2%) Query: 11 IKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVI 70 +K L+ + + + +++LR G +++ + E+L I + I +RSRT +T+DVI Sbjct: 6 VKALITDPIDEILIKTLREKG-IQVDYMPE-ISKEELLNIIGNYDIIVVRSRTKVTKDVI 63 Query: 71 NAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEA 130 +KL I IG + +D + A KR I V AP ++T S EL IG ++ R + + Sbjct: 64 EKGKKLKIIARAGIGLDNIDTEEAEKRNIKVVYAPGASTDSAVELTIGLMIAAARKMYTS 123 Query: 131 NAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDI--ENKLPL 188 A A G++ K+ E GK +GI+G+G IGT++GI+A ++GM V YDI + Sbjct: 124 MALAKSGIFKKIE--GLELAGKTIGIVGFGRIGTKVGIIANAMGMKVLAYDILDIREKAE 181 Query: 189 GNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPA 248 + L +LL SDV+SLHV + K ++ + LMK +++N SR V+ A Sbjct: 182 KINAKAVSLEELLKNSDVISLHVTVSKDAKPIIDYPQFELMKDNVIIVNTSRAVAVNGKA 241 Query: 249 LCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEV 308 L D + + A DVF EP + + L + + V++T HIG T+EAQ+ + Sbjct: 242 LLDYIKKGKVYAYATDVFWNEP--PKEEWELELLKHERVIVTTHIGAQTKEAQKRVAEMT 299 Query: 309 AGKLIKYSD 317 L+ Sbjct: 300 TQNLLNAMK 308 >4CUK-A nrPDB Length = 338 Score = 285 bits (729), Expect = 2e-77, Method: Composition-based stats. Identities = 82/328 (25%), Positives = 133/328 (40%), Gaps = 13/328 (3%) Query: 10 KIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDV 69 K+ + +K L+ + A +EF L E+ ++ + + + V Sbjct: 2 KLAVYSTKQYDKKYLQQVNEAFGFELEFFDFLLT-EKTAKTANGCEAVCIFVNDDGSRPV 60 Query: 70 INAAEK--LVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGV 127 + +K + I C G N VDLDAA + G+ V P + +VAE IG ++ L R + Sbjct: 61 LEELKKHGVKYIALRCAGFNNVDLDAAKELGLQVVRVPAYSPEAVAEHAIGMMMTLNRRI 120 Query: 128 PEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYD-IENKL 186 A + ++ F GK G+IG G IG + + GM + +D + Sbjct: 121 HRAYQRTRDANFSLEGLTGFTMHGKTAGVIGTGKIGVAALRILKGFGMRLLAFDPYPSTA 180 Query: 187 PLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDI 246 L + L L SDV+SLH P P +++ MK G ++IN SRG ++D Sbjct: 181 ALDLGVEYVDLQTLFAESDVISLHCPLTPENYHLLNHAAFDQMKNGVMIINTSRGALIDS 240 Query: 247 PALCDALASKHLAGAAIDVFPTEPATN---------SDPFTSPLCEFDNVLLTPHIGGST 297 A +AL ++ + +DV+ E D L NVL T H T Sbjct: 241 QAAIEALKNQKIGSLGMDVYENERDLFFEDKSVDVIQDDVFRRLSACHNVLFTGHQAFLT 300 Query: 298 QEAQENIGLEVAGKLIKYSDNGSTLSAV 325 EA +I L + + +A+ Sbjct: 301 AEALISISETTLQNLSQLEKGEACPNAL 328 >5Z1Z-A nrPDB Length = 329 Score = 284 bits (726), Expect = 6e-77, Method: Composition-based stats. Identities = 79/328 (24%), Positives = 133/328 (40%), Gaps = 13/328 (3%) Query: 10 KIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDV 69 K+ + +K L+ + + +EF L E+ ++ + + + V Sbjct: 2 KLAVYSTKQYDKKYLQQVNESFGFELEFFDFLLT-EKTAKTANGCEAVCIFVNDDGSRPV 60 Query: 70 INAAEK--LVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGV 127 + +K + I C G N VDLDAA + G+ V P + +VAE IG ++ L R + Sbjct: 61 LEELKKHGVKYIALRCAGFNNVDLDAAKELGLKVVRVPAYDPEAVAEHAIGMMMTLNRRI 120 Query: 128 PEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYD-IENKL 186 A + ++ F GK G+IG G IG + + + GM + +D + Sbjct: 121 HRAYQRTRDANFSLEGLTGFTMYGKTAGVIGTGKIGVAMLRILKGFGMRLLAFDPYPSAA 180 Query: 187 PLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDI 246 L + L L + SDV+SLH P P +++ MK G +++N SRG ++D Sbjct: 181 ALELGVEYVDLPTLFSESDVISLHCPLTPENYHLLNEAAFDQMKNGVMIVNTSRGALIDS 240 Query: 247 PALCDALASKHLAGAAIDVFPTEPATN---------SDPFTSPLCEFDNVLLTPHIGGST 297 A +AL ++ + +DV+ E D L NVL T H T Sbjct: 241 QAAIEALKNQKIGSLGMDVYENERDLFFEDKSNDVIQDDVFRRLSACHNVLFTGHQAFLT 300 Query: 298 QEAQENIGLEVAGKLIKYSDNGSTLSAV 325 EA +I L + + + Sbjct: 301 AEALTSISQTTLQNLSNLEKGETCPNEL 328 >2CUK-A nrPDB Length = 311 Score = 282 bits (722), Expect = 2e-76, Method: Composition-based stats. Identities = 95/318 (29%), Positives = 150/318 (47%), Gaps = 11/318 (3%) Query: 11 IKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVI 70 ++ L+ + KAL+ LR G L +L + + A + + +V+ Sbjct: 1 MRVLVTRTLPGKALDRLRERGLEVEVHRGLFLPKAELLKRVEGAVGLIPTVEDRIDAEVM 60 Query: 71 NAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEA 130 + A+ L I C+ +G + VDL+AA +RGI V + P T + A+L + LL + R V E Sbjct: 61 DRAKGLKVIACYSVGVDHVDLEAARERGIRVTHTPGVLTEATADLTLALLLAVARRVVEG 120 Query: 131 NAKAHRGVWN---KLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLP 187 A A G+W + +G LG++G G IG + A + GM V ++ K Sbjct: 121 AAYARDGLWKAWHPELLLGLDLQGLTLGLVGMGRIGQAVAKRALAFGMRVVYHARTPKPL 180 Query: 188 LGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIP 247 L +LL +DVVSLH P P T ++ + + MK G++L+N +RG +VD Sbjct: 181 ---PYPFLSLEELLKEADVVSLHTPLTPETHRLLNRERLFAMKRGAILLNTARGALVDTE 237 Query: 248 ALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLE 307 AL +AL HL GA +DV EP P PL N ++TPHIG + + +E + Sbjct: 238 ALVEALR-GHLFGAGLDVTDPEPL----PPGHPLYALPNAVITPHIGSAGRTTRERMAEV 292 Query: 308 VAGKLIKYSDNGSTLSAV 325 L+ + + V Sbjct: 293 AVENLLAVLEGREPPNPV 310 >3DC2-A nrPDB Length = 529 Score = 282 bits (722), Expect = 2e-76, Method: Composition-based stats. Identities = 103/318 (32%), Positives = 160/318 (50%), Gaps = 10/318 (3%) Query: 11 IKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVI 70 L+ + + + +L G D ++L ++ +A + +RS T + +V+ Sbjct: 5 PVVLIADKLAPSTVAAL---GDQVEVRWVDGPDRDKLLAAVPEADALLVRSATTVDAEVL 61 Query: 71 NAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEA 130 AA KL + +G + VD+DAA RG+ V NAP SN S AE + LL R +P A Sbjct: 62 AAAPKLKIVARAGVGLDNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAASRQIPAA 121 Query: 131 NAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYD--IENKLPL 188 +A W + + E GK +G++G G IG + + G YV YD + Sbjct: 122 DASLREHTWKRSSFSGTEIFGKTVGVVGLGRIGQLVAQRIAAFGAYVVAYDPYVSPARAA 181 Query: 189 GNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPA 248 ++ L DLL +D +S+H+P+ P T ++ + ++ KPG +++NA+RG +VD A Sbjct: 182 QLGIELLSLDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAA 241 Query: 249 LCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEV 308 L DA+ H+ A +DVF TEP T SPL E V++TPH+G ST EAQ+ G +V Sbjct: 242 LADAITGGHVRAAGLDVFATEPCT-----DSPLFELAQVVVTPHLGASTAEAQDRAGTDV 296 Query: 309 AGKLIKYSDNGSTLSAVN 326 A + AVN Sbjct: 297 AESVRLALAGEFVPDAVN 314 Score = 29.5 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 1/76 (1%) Query: 324 AVNFPEVSLPLHGGRRLMHIHENRPGVLTALNKIFAEQGVNIAAQYLQTSAQMGYVVIDI 383 +N L G ++H + +RPG L + + GVNI A L A+ I + Sbjct: 442 QINGRHFDLRAQGINLIIH-YVDRPGALGKIGTLLGTAGVNIQAAQLSEDAEGPGATILL 500 Query: 384 EADEDVAEKALQAMKA 399 D+DV + A+ A Sbjct: 501 RLDQDVPDDVRTAIAA 516 >6ABJ-A nrPDB Length = 345 Score = 280 bits (717), Expect = 7e-76, Method: Composition-based stats. Identities = 82/287 (28%), Positives = 127/287 (44%), Gaps = 13/287 (4%) Query: 51 IRDAHFIGLRSRTHLTEDVIN--AAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSN 108 + + L+ V+ AA + G N VDL AA G+PV + P + Sbjct: 58 AQGFEVVCAFVNDDLSRPVLERLAAGGTRLVALRSAGYNHVDLAAAEALGLPVVHVPAYS 117 Query: 109 TRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGI 168 +VAE +G +L L R + A + G ++ F+ GK++G+IG G IG Sbjct: 118 PHAVAEHAVGLILTLNRRLHRAYNRTREGDFSLHGLTGFDLHGKRVGVIGTGQIGETFAR 177 Query: 169 LAESLGMYVYFYD-IENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEIS 227 + G + YD N + L LL SD+VSLH P T++++ A+ ++ Sbjct: 178 IMAGFGCELLAYDPYPNPRIQALGGRYLALDALLAESDIVSLHCPLTADTRHLIDAQRLA 237 Query: 228 LMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATN---------SDPFT 278 MKPG++LIN RG +V+ AL +AL S L +DV+ E D Sbjct: 238 TMKPGAMLINTGRGALVNAAALIEALKSGQLGYLGLDVYEEEADIFFEDRSDQPLQDDVL 297 Query: 279 SPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDNGSTLSAV 325 + L F NV++T H T+EA I + + D G+ + V Sbjct: 298 ARLLSFPNVVVTAHQAFLTREALAAIADTTLDNIAAWQD-GTPRNRV 343 >3BA1-A nrPDB Length = 333 Score = 279 bits (715), Expect = 1e-75, Method: Composition-based stats. Identities = 87/318 (27%), Positives = 141/318 (44%), Gaps = 8/318 (2%) Query: 9 DKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTED 68 + I L++ + + L + + + L + S + Sbjct: 22 EAIGVLMMCPMSTYLEQELDKR-FKLFRYWTQPAQRDFLALQAESIRAVVGNSNAGADAE 80 Query: 69 VINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVP 128 +I+A KL + F +G ++VDL ++G+ V N P T VA+L IG +L +LR + Sbjct: 81 LIDALPKLEIVSSFSVGLDKVDLIKCEEKGVRVTNTPDVLTDDVADLAIGLILAVLRRIC 140 Query: 129 EANAKAHRGVWN-KLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLP 187 E + RG W + + GK++GIIG G IG + AE+ + ++ K P Sbjct: 141 ECDKYVRRGAWKFGDFKLTTKFSGKRVGIIGLGRIGLAVAERAEAFDCPISYFSRSKK-P 199 Query: 188 LGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIP 247 N T + +L + SD++ + P P T +++ + I + P +LIN RG VD P Sbjct: 200 NTNYTYYGSVVELASNSDILVVACPLTPETTHIINREVIDALGPKGVLINIGRGPHVDEP 259 Query: 248 ALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLE 307 L AL L GA +DVF EP L +NV+L PH+G T E ++ + Sbjct: 260 ELVSALVEGRLGGAGLDVFEREPEVPEK-----LFGLENVVLLPHVGSGTVETRKVMADL 314 Query: 308 VAGKLIKYSDNGSTLSAV 325 V G L + L+ V Sbjct: 315 VVGNLEAHFSGKPLLTPV 332 >4ZGS-A nrPDB Length = 386 Score = 278 bits (712), Expect = 3e-75, Method: Composition-based stats. Identities = 88/303 (29%), Positives = 133/303 (43%), Gaps = 19/303 (6%) Query: 32 YTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVINAAEK--LVAIGCFCIGTNQV 89 +T+ F + LD + + R L VI K + I C G ++V Sbjct: 58 FTDTYFVEPPLDKDT-AQLARGYDVAVLFVNDRADASVIKELAKAGVKLIALRCAGFDRV 116 Query: 90 DLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEA 149 DL A A+ G+ V P + SVAE + + L R + +A + G ++ E Sbjct: 117 DLHACAEHGVRVVRVPTYSPESVAEHAVALIFALNRHLTDAYIRVRMGNYSLSGLVGVEM 176 Query: 150 RGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLP-LGNATQVQHLSDLLNMSDVVS 208 R K +G++G G IG Q + + +G V+ YDI+ L +LL MSD+V+ Sbjct: 177 RHKVVGVVGTGAIGQQAARILKGIGCKVFAYDIKPNPAVEAMGIPYVSLDELLAMSDIVT 236 Query: 209 LHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPT 268 LH P PST+ ++ + I MK G +LIN SRG ++D AL DAL S + +DV+ Sbjct: 237 LHCPLLPSTRQLINKESIQKMKKGVMLINVSRGGLIDSAALFDALESGQIGALGLDVYEN 296 Query: 269 E------------PATNSDPFT---SPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLI 313 E P+ + L + VL+TPH T+EA NI + Sbjct: 297 EGGLFFVDHTKFDPSVRMQKWDRQFRTLLSYPQVLVTPHTAFLTEEALNNICTTTIQNIA 356 Query: 314 KYS 316 Y Sbjct: 357 DYV 359 >1GDH-A nrPDB Length = 320 Score = 277 bits (708), Expect = 8e-75, Method: Composition-based stats. Identities = 84/322 (26%), Positives = 136/322 (42%), Gaps = 14/322 (4%) Query: 10 KIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDV 69 K K L+ + + A+ R + + +++ E+ + + + ++V Sbjct: 1 KKKILITWPLPEAAMARARESYDVIAHGDDPKITIDEMIETAKSVDALLITLNEKCRKEV 60 Query: 70 INAAE-KLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVP 128 I+ + I + IG + +DLDA RGI V NAP T + AE+ + LL R Sbjct: 61 IDRIPENIKCISTYSIGFDHIDLDACKARGIKVGNAPHGVTVATAEIAMLLLLGSARRAG 120 Query: 129 EANAKAHRG---VWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENK 185 E W L + K LGI G+G IG L A+ M + ++D Sbjct: 121 EGEKMIRTRSWPGWEPLELVGEKLDNKTLGIYGFGSIGQALAKRAQGFDMDIDYFDTHRA 180 Query: 186 LPLGNATQ----VQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRG 241 A+ L LL++S SL+ P P T+ I + G++++N +RG Sbjct: 181 SSSDEASYQATFHDSLDSLLSVSQFFSLNAPSTPETRYFFNKATIKSLPQGAIVVNTARG 240 Query: 242 TVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQ 301 +VD + AL + LA A DVF EP N + N L PHIG + +A+ Sbjct: 241 DLVDNELVVAALEAGRLAYAGFDVFAGEPNINEGYYD-----LPNTFLFPHIGSAATQAR 295 Query: 302 ENIGLEVAGKLIKYSDNGSTLS 323 E++ + A LI G+ +S Sbjct: 296 EDMAHQ-ANDLIDALFGGADMS 316 >1J49-A nrPDB Length = 333 Score = 274 bits (702), Expect = 3e-74, Method: Composition-based stats. Identities = 81/321 (25%), Positives = 134/321 (41%), Gaps = 22/321 (6%) Query: 29 AAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVINAA--EKLVAIGCFCIGT 86 A +E+ L E + + A + + + + + A + + +G Sbjct: 23 AHKDVEVEYTDKLLTPETV-ALAKGADGVVVYQQLDYIAETLQALADNGITKMSLRNVGV 81 Query: 87 NQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGS 146 + +D+ A + G + N P + ++AE + +LR + K R Sbjct: 82 DNIDMAKAKELGFQITNVPVYSPNAIAEHAAIQAARILRQDKAMDEKVARHDLRWAPTIG 141 Query: 147 FEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGN-ATQVQHLSDLLNMSD 205 E R + +G++G GHIG + E G V YDI L V L DL +D Sbjct: 142 REVRDQVVGVVGTGHIGQVFMQIMEGFGAKVITYDIFRNPELEKKGYYVDSLDDLYKQAD 201 Query: 206 VVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDV 265 V+SLHVP+ P+ +M+ + I+ MK +++N SRG +VD A+ L S + G A+DV Sbjct: 202 VISLHVPDVPANVHMINDESIAKMKQDVVIVNVSRGPLVDTDAVIRGLDSGKIFGYAMDV 261 Query: 266 FPTEPATNSDPFT---------SPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYS 316 + E ++ + + L NVL+TPH T A N+ ++K Sbjct: 262 YEGEVGIFNEDWEGKEFPDARLADLIARPNVLVTPHTAFYTTHAVRNM-------VVKAF 314 Query: 317 DNGSTLSAVNFPEVSLPLHGG 337 DN L V E P+ G Sbjct: 315 DN--NLELVEGKEAETPVKVG 333 >2DLD-A nrPDB Length = 337 Score = 269 bits (687), Expect = 2e-72, Method: Composition-based stats. Identities = 77/310 (24%), Positives = 132/310 (42%), Gaps = 13/310 (4%) Query: 28 RAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVINAAE--KLVAIGCFCIG 85 A ++++ L E + + A + + + T D + A + + +G Sbjct: 22 EAHKDIDVDYTDKLLTPET-AKLAKGADGVVVYQQLDYTADTLQALADAGVTKMSLRNVG 80 Query: 86 TNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAG 145 + +D+D A + G + N P + ++AE + +LR + K + Sbjct: 81 VDNIDMDKAKELGFQITNVPVYSPNAIAEHAAIQAARVLRQDKRMDEKMAKRDLRWAPTI 140 Query: 146 SFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLG-NATQVQHLSDLLNMS 204 E R + +G++G GHIG + E G V YDI L V L DL + Sbjct: 141 GREVRDQVVGVVGTGHIGQVFMRIMEGFGAKVIAYDIFKNPELEKKGYYVDSLDDLYKQA 200 Query: 205 DVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAID 264 DV+SLHVP+ P+ +M+ K I+ MK G +++N SRG +VD A+ L S + G +D Sbjct: 201 DVISLHVPDVPANVHMINDKSIAEMKDGVVIVNCSRGRLVDTDAVIRGLDSGKIFGFVMD 260 Query: 265 VFPTEPATNSDPFT---------SPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKY 315 + E + + + L + NVL+TPH T A N+ ++ +K Sbjct: 261 TYEDEVGVFNKDWEGKEFPDKRLADLIDRPNVLVTPHTAFYTTHAVRNMVVKAFNNNLKL 320 Query: 316 SDNGSTLSAV 325 + S V Sbjct: 321 INGEKPDSPV 330 >3JTM-A nrPDB Length = 351 Score = 269 bits (687), Expect = 2e-72, Method: Composition-based stats. Identities = 83/310 (26%), Positives = 143/310 (46%), Gaps = 12/310 (3%) Query: 23 ALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRS--RTHLTEDVINAAEKLVAIG 80 + L + G+ I D +L++ I D H + ++T + I A+ L + Sbjct: 32 IRDWLESQGHQYIVTDDKEGPDCELEKHIPDLHVLISTPFHPAYVTAERIKKAKNLKLLL 91 Query: 81 CFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWN 140 IG++ +DL AAA G+ V SN SVAE + +L+L+R + +G WN Sbjct: 92 TAGIGSDHIDLQAAAAAGLTVAEVTGSNVVSVAEDELMRILILMRNFVPGYNQVVKGEWN 151 Query: 141 --KLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPL----GNATQV 194 +A +++ GK +G +G G IG L + G + ++D P A V Sbjct: 152 VAGIAYRAYDLEGKTIGTVGAGRIGKLLLQRLKPFGCNLLYHDRLQMAPELEKETGAKFV 211 Query: 195 QHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALA 254 + L+++L DV+ +++P T+ M + I +K G L++N +RG +++ A+ DA+ Sbjct: 212 EDLNEMLPKCDVIVINMPLTEKTRGMFNKELIGKLKKGVLIVNNARGAIMERQAVVDAVE 271 Query: 255 SKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIK 314 S H+ G + DV+ +PA P P N +TPH G+T +AQ L + Sbjct: 272 SGHIGGYSGDVWDPQPA----PKDHPWRYMPNQAMTPHTSGTTIDAQLRYAAGTKDMLER 327 Query: 315 YSDNGSTLSA 324 Y + Sbjct: 328 YFKGEDFPTE 337 >4G2N-A nrPDB Length = 345 Score = 269 bits (687), Expect = 2e-72, Method: Composition-based stats. Identities = 79/307 (25%), Positives = 126/307 (41%), Gaps = 11/307 (3%) Query: 12 KFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVIN 71 K L LR + L + A + + + +T +VI Sbjct: 30 KAFLCRRFTPAIEAELRQRFDLEVNLEDTVLTPSGIASRAHGAEVLFVTATEAITAEVIR 89 Query: 72 AA-EKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEA 130 L I +G + +D+ AA GI V + P + + AE+ + +L R EA Sbjct: 90 KLQPGLKTIATLSVGYDHIDMAAARSLGIKVLHTPDVLSDACAEIAMLLVLNACRRGYEA 149 Query: 131 NAKAHRGVWNKLAAG---SFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIEN--K 185 + G W G++LGI G G IG + A G+ +++++ Sbjct: 150 DRMVRSGSWPGWGPTQLLGMGLTGRRLGIFGMGRIGRAIATRARGFGLAIHYHNRTRLSH 209 Query: 186 LPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVD 245 A L LL SD+ + P P K + I+ + G+++IN SRG +++ Sbjct: 210 ALEEGAIYHDTLDSLLGASDIFLIAAPGRPELKGFLDHDRIAKIPEGAVVINISRGDLIN 269 Query: 246 IPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIG 305 AL +AL SKHL A +DVF EPA DN+ LTPHIG +T E ++ +G Sbjct: 270 DDALIEALRSKHLFAAGLDVFANEPAI-----DPRYRSLDNIFLTPHIGSATHETRDAMG 324 Query: 306 LEVAGKL 312 + + Sbjct: 325 WLLIQGI 331 >5UOG-A nrPDB Length = 344 Score = 267 bits (682), Expect = 8e-72, Method: Composition-based stats. Identities = 88/332 (26%), Positives = 142/332 (42%), Gaps = 18/332 (5%) Query: 7 EKDKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLT 66 + + L+ ++ + LE L + + + D + +RD I + + + Sbjct: 22 SMSRPRILVPGKINPRVLERLPEM-FETVRIERA--DAALVTADMRDVSGIAVSGKLPVP 78 Query: 67 EDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRG 126 +++A L + F +G + VD+ AA RGI V N P T VA+ IG LL LR Sbjct: 79 --LMDAFPSLEIVANFGVGYDGVDVSRAAARGIVVTNTPDVLTEEVADTAIGLLLNTLRL 136 Query: 127 VPEANAKAHRGVWNKLA---AGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIE 183 +P+A +G W + RG+ +G+ G G IG + E+ G+ + ++ Sbjct: 137 LPQAEQWLRQGRWVREGAFPLSPLSLRGRTVGLFGLGRIGLAIARRLEAFGVSIAYHTRT 196 Query: 184 NKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTV 243 + LG T L + D + + VP ST + A +S + P +LIN RG+ Sbjct: 197 PREGLG-FTYHPTLVGMAEAVDTLIVIVPGTASTLKAVNADVLSALGPKGVLINVGRGST 255 Query: 244 VDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQEN 303 VD AL AL + +AGA +DVF EP L F NV L PH+ ++ + Sbjct: 256 VDEAALVTALQNGTIAGAGLDVFENEPNVPE-----ALLSFPNVSLLPHVASASVVTRNA 310 Query: 304 IGLEVAGKLIKYSDNGSTLSAVNFPEVSLPLH 335 + V L + G L+ V P Sbjct: 311 MSDLVVDNLKAWFSTGEALTPV----AETPFR 338 >4NFY-A nrPDB Length = 307 Score = 267 bits (682), Expect = 8e-72, Method: Composition-based stats. Identities = 86/322 (26%), Positives = 140/322 (43%), Gaps = 31/322 (9%) Query: 10 KIKFLLVEGVHQKAL----ESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHL 65 KI + + + A+ E L AG+ + K E + E I+DA + +RS + Sbjct: 2 KIVVITEKPFAENAVKGIREILEKAGHEVVMIEK-YKKKEDVIERIKDADGVIVRS-DKI 59 Query: 66 TEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLR 125 E++I A EK+ I G + +D++A + I V N P N VAEL IG ++ R Sbjct: 60 DEEIIKAGEKVKIIVRAGAGYDNIDIEACNQGKIVVMNTPGQNRNGVAELCIGMMIFGFR 119 Query: 126 GVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENK 185 G E + K LGI G G++G ++ +AE +GM + YD Sbjct: 120 KG------FKEGK-------GRELKDKTLGICGCGYVGKRVKEIAEGIGMKIKVYDPF-- 164 Query: 186 LPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVD 245 + QV+ + +L V+SLH+P TK +G + I + G ++ N +R ++D Sbjct: 165 --ITTENQVKKIEELFEECQVISLHLPLTKETKGKIGYELIKKLPYGGMICNTARKEIID 222 Query: 246 IPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTP-HIGGSTQEAQENI 304 L + + DV PT N++ TP IG T+E+ N Sbjct: 223 EEGLIRIMREREDLIYITDVAPTSKVFNNEFKGR-------FFATPIKIGAETEESNINA 275 Query: 305 GLEVAGKLIKYSDNGSTLSAVN 326 G+ A ++ + NG+ VN Sbjct: 276 GMAAASQICDFFTNGTVKFQVN 297 >4XYG-A nrPDB Length = 391 Score = 264 bits (674), Expect = 6e-71, Method: Composition-based stats. Identities = 80/304 (26%), Positives = 133/304 (43%), Gaps = 12/304 (3%) Query: 23 ALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRS--RTHLTEDVINAAEKLVAIG 80 L G+T I + ++ + DA + + +LT + I A+KL Sbjct: 60 LRSYLEDLGHTFIVTSDKEGPNSVFEKELPDADIVISQPFWPAYLTAERIAKAKKLKLAL 119 Query: 81 CFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWN 140 IG++ VDL+AA K GI V FSN VAE + +L L+R ++ A G WN Sbjct: 120 TAGIGSDHVDLNAAIKAGITVAEETFSNGICVAEHAVMMILALVRNYLPSHKIAEEGGWN 179 Query: 141 --KLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNA----TQV 194 + S++ G +G + G IG + + + +++ T Sbjct: 180 IADCVSRSYDLEGMHVGTVAAGRIGLAVLRRLKPFDVKLHYTARHRSPRAIEDELGLTYH 239 Query: 195 QHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALA 254 ++ + DV+S+H P P+T+++ AK ++ M+ GS L+N +R + D + AL Sbjct: 240 ATAEEMAEVCDVISIHAPLYPATEHLFNAKVLNKMRHGSYLVNTARAEICDRDDIVRALE 299 Query: 255 SKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIK 314 S LAG A DV+ +PA P P + +TPH+ GS+ Q L Sbjct: 300 SGQLAGYAGDVWFPQPA----PANHPWRNMPHNGMTPHMSGSSLSGQARYAAGTREILEC 355 Query: 315 YSDN 318 + +N Sbjct: 356 WFEN 359 >6D4C-A nrPDB Length = 364 Score = 264 bits (674), Expect = 7e-71, Method: Composition-based stats. Identities = 74/304 (24%), Positives = 137/304 (45%), Gaps = 12/304 (3%) Query: 27 LRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRS--RTHLTEDVINAAEKLVAIGCFCI 84 L+ G+ I + L + I DA I ++T++ I+ A+KL + + Sbjct: 34 LKDQGHELITTSDKEGGNSVLDQHIPDADIIITTPFHPAYITKERIDKAKKLKLVVVAGV 93 Query: 85 GTNQVDLDAAAKRG--IPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWN-- 140 G++ +DLD + G I V SN S AE V+ +L+L+R A+ + W Sbjct: 94 GSDHIDLDYINQTGKKISVLEVTGSNVVSGAEHVLMTMLVLVRNFVPAHEQIINHDWEVA 153 Query: 141 KLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMY-VYFYDIE----NKLPLGNATQVQ 195 +A +++ GK + IG G IG ++ + +YD + + A +V+ Sbjct: 154 AIAKDAYDIEGKTIATIGAGRIGYRVLERLVPFNPKELLYYDYQALPKDAEEKVGARRVE 213 Query: 196 HLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALAS 255 ++ +L+ +D+V+++ P + TK ++ + +S K G+ L+N +RG + + AL S Sbjct: 214 NIEELVAQADIVTINAPLHAGTKGLINKELLSKFKKGAWLVNTARGAICVAEDVAAALES 273 Query: 256 KHLAGAAIDVFPTEPATNSDPFTSPLCEF-DNVLLTPHIGGSTQEAQENIGLEVAGKLIK 314 L G DV+ +PA P+ ++ +TPH G+T +AQ L Sbjct: 274 GQLRGYGGDVWFPQPAPKDHPWRDMRNKYGAGNAMTPHYSGTTLDAQTRYAEGTKNILES 333 Query: 315 YSDN 318 + Sbjct: 334 FFTG 337 >1HL3-A nrPDB Length = 358 Score = 263 bits (673), Expect = 9e-71, Method: Composition-based stats. Identities = 80/303 (26%), Positives = 135/303 (44%), Gaps = 13/303 (4%) Query: 34 NIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDA 93 + F E ++ + +A + LT + + + L I G + +D+ + Sbjct: 47 TVAFCDAQSTQEIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKS 106 Query: 94 AAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGV-------WNKLAAGS 146 A GI V N P ++ A+ + +L L R + G ++A+G+ Sbjct: 107 AGDLGIAVCNVPAASVEETADSTLCHILNLYRRTTWLHQALREGTRVQSVEQIREVASGA 166 Query: 147 FEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNAT---QVQHLSDLLNM 203 RG+ LGIIG G +G + + A++ G V FYD + A +V L DLL Sbjct: 167 ARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGIERALGLQRVSTLQDLLFH 226 Query: 204 SDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAI 263 SD V+LH N +++ + M+ G+ L+N +RG +VD AL AL + GAA+ Sbjct: 227 SDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAAL 286 Query: 264 DVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDNGSTLS 323 DV +EP + S PL + N++ TPH +++A + E A ++ + S Sbjct: 287 DVHESEPFSFSQ---GPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITGRIPDS 343 Query: 324 AVN 326 N Sbjct: 344 LKN 346 >2YQ5-A nrPDB Length = 343 Score = 261 bits (668), Expect = 4e-70, Method: Composition-based stats. Identities = 86/334 (25%), Positives = 140/334 (41%), Gaps = 19/334 (5%) Query: 10 KIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDV 69 KI V + +E I+ AL + + + L+ + E+V Sbjct: 3 KIAMYNVSPIEVPYIEDWAKKNDVEIKTTDQALTSATV-DLAEGCSSVSLKPLGPVDEEV 61 Query: 70 INAAEKL-----VAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLL 124 + +KL IG +G N ++ D K + V N P + R++AE+ + + + LL Sbjct: 62 V--YQKLSEYGVKCIGLRIVGFNTINFDWTKKYNLLVTNVPVYSPRAIAEMTVTQAMYLL 119 Query: 125 RGVPEANAKA-HRGVWNK-LAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDI 182 R + E + H + S E +G+IG GHIG+ + + ++G V YD+ Sbjct: 120 RKIGEFRYRMDHDHDFTWPSNLISNEIYNLTVGLIGVGHIGSAVAEIFSAMGAKVIAYDV 179 Query: 183 ENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGT 242 +L +D+VSLH P PST+NM+G K++ MK + LIN +RG Sbjct: 180 AYNPEFEPFLTYTDFDTVLKEADIVSLHTPLFPSTENMIGEKQLKEMKKSAYLINCARGE 239 Query: 243 VVDIPALCDALASKHLAGAAIDVFPTEPATNSD---------PFTSPLCEFDNVLLTPHI 293 +VD AL AL +AGA +D E + L + NV++TPH Sbjct: 240 LVDTGALIKALQDGEIAGAGLDTLAGESSYFGHTGLTDSEIPEDYKTLAKMPNVVITPHS 299 Query: 294 GGSTQEAQENIGLEVAGKLIKYSDNGSTLSAVNF 327 T+ + N+ + + G S VN Sbjct: 300 AFYTETSIRNMVQICLTDQLTIAKGGRPRSIVNL 333 >5OFW-B nrPDB Length = 223 Score = 261 bits (667), Expect = 4e-70, Method: Composition-based stats. Identities = 79/227 (34%), Positives = 115/227 (50%), Gaps = 8/227 (3%) Query: 101 VFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYG 160 V N P N+ S AEL G ++ L R +P+A A G W + E GK LGI+G G Sbjct: 3 VMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLG 62 Query: 161 HIGTQLGILAESLGMYVYFYD--IENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTK 218 IG ++ +S GM YD I ++ Q L ++ + D +++H P PST Sbjct: 63 RIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTT 122 Query: 219 NMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFT 278 ++ + K G ++N +RG +VD AL AL S AGAA+DVF EP P Sbjct: 123 GLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEP-----PRD 177 Query: 279 SPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDNGSTLSAV 325 L + +NV+ PH+G ST+EAQ G E+A + + G +L+ V Sbjct: 178 RALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMV-KGKSLTGV 223 >2OME-A nrPDB Length = 336 Score = 261 bits (667), Expect = 5e-70, Method: Composition-based stats. Identities = 85/327 (25%), Positives = 141/327 (43%), Gaps = 14/327 (4%) Query: 10 KIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDV 69 + L++G +E + F E ++ + +A + LT + Sbjct: 5 RPLVALLDGRD-CTVEMPILKDLATVAFCDAQSTQEIHEKVLNEAVGAMMYHTITLTRED 63 Query: 70 INAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPE 129 + + L I G + VD+ AA + GI V N P + A+ I +L L R Sbjct: 64 LEKFKALRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTW 123 Query: 130 ANAKAHRGV-------WNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDI 182 G ++A+G+ RG+ LG+IG+G G + + A++ G V FYD Sbjct: 124 LYQALREGTRVQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDP 183 Query: 183 ENKLPLG---NATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINAS 239 + + +V L DLL SD VSLH N +++ I M+ G+ L+NA+ Sbjct: 184 YLQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAA 243 Query: 240 RGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQE 299 RG +VD AL AL + GAA+DV +EP + + PL + N++ TPH +++ Sbjct: 244 RGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQ---GPLKDAPNLICTPHTAWYSEQ 300 Query: 300 AQENIGLEVAGKLIKYSDNGSTLSAVN 326 A + A ++ + S N Sbjct: 301 ASLEMREAAATEIRRAITGRIPESLRN 327 >4LSW-A nrPDB Length = 318 Score = 259 bits (662), Expect = 2e-69, Method: Composition-based stats. Identities = 82/289 (28%), Positives = 127/289 (43%), Gaps = 8/289 (2%) Query: 40 GALDDEQLKESIRDA-HFIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRG 98 A D + ++ D I R + +I A L I + +G + VDL A +RG Sbjct: 31 EADDRAAMLANVGDRIRAIATRGELGASRALIEACPNLELISVYGVGYDAVDLAACRERG 90 Query: 99 IPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEAR--GKKLGI 156 I V N P T VA+L + +L RG+ A A G W + R G++ G+ Sbjct: 91 IQVTNTPDVLTGDVADLGVAMMLAQSRGIIGAETWARSGKWAAEGLYPLKRRVFGRRAGV 150 Query: 157 IGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPS 216 +G G IG ++ M + + DI K + T V+ L D + + + + + Sbjct: 151 LGLGRIGFEVARRLAGFDMQISYSDIAPKSYAPDWTFVEDAVTLARDVDFLFVTLAASAA 210 Query: 217 TKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDP 276 T++++G I + P +LIN SR + +D AL ALA L AA+DVF EP Sbjct: 211 TRHIVGRDVIEALGPEGMLINISRASNIDEEALIAALADGRLGSAALDVFEGEPN----- 265 Query: 277 FTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDNGSTLSAV 325 F + NVLL PH T E ++ +G + L + L+ V Sbjct: 266 FDPRFRDLPNVLLQPHHASGTIETRKAMGQLLRDNLTAHFAGSPLLTPV 314 >4DGS-A nrPDB Length = 340 Score = 259 bits (661), Expect = 2e-69, Method: Composition-based stats. Identities = 92/319 (28%), Positives = 151/319 (47%), Gaps = 10/319 (3%) Query: 10 KIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDV 69 K LLVE + ++ L+ Y+ ++ A D L+ ++ + L+ + Sbjct: 30 KPDLLLVEPMMPFVMDELQ-RNYSVHRLYQAA-DRPALEAALPSIRAVATGGGAGLSNEW 87 Query: 70 INAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPE 129 + L I +GT++VDL A +R I V P VA+L I +L +LR V + Sbjct: 88 MEKLPSLGIIAINGVGTDKVDLARARRRNIDVTTTPGVLADDVADLGIALMLAVLRRVGD 147 Query: 130 ANAKAHRGVWNKLA--AGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLP 187 + G W +GK++G++G G IG L AE+ GM V +++ Sbjct: 148 GDRLVREGRWAAGEQLPLGHSPKGKRIGVLGLGQIGRALASRAEAFGMSVRYWNRSTLSG 207 Query: 188 LGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIP 247 + + Q DL SDV+++ V + +T+N++ A + + P +++N +RG VVD Sbjct: 208 V-DWIAHQSPVDLARDSDVLAVCVAASAATQNIVDASLLQALGPEGIVVNVARGNVVDED 266 Query: 248 ALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLE 307 AL +AL S +AGA +DVF EPA S+ T+P N +L PH G +T E + +G Sbjct: 267 ALIEALKSGTIAGAGLDVFVNEPAIRSEFHTTP-----NTVLMPHQGSATVETRMAMGKL 321 Query: 308 VAGKLIKYSDNGSTLSAVN 326 V L + + VN Sbjct: 322 VLANLAAHFAGEKAPNTVN 340 >1XDW-A nrPDB Length = 331 Score = 259 bits (661), Expect = 2e-69, Method: Composition-based stats. Identities = 73/311 (23%), Positives = 134/311 (43%), Gaps = 14/311 (4%) Query: 28 RAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVINAAEKL--VAIGCFCIG 85 + GY I+ L+ ++ E + LR + ++ +KL I G Sbjct: 21 KEFGYD-IKCVPDYLNTKETAEMAAGFDAVILRGNCFANKQNLDIYKKLGVKYILTRTAG 79 Query: 86 TNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAG 145 T+ +D + A + G P+ P + ++AEL + + ++LLR ++ + + A Sbjct: 80 TDHIDKEYAKELGFPMAFVPRYSPNAIAELAVTQAMMLLRHTAYTTSRTAKKNFKVDAFM 139 Query: 146 -SFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMS 204 S E R +G++G G IG + +G V D+ + + L ++L S Sbjct: 140 FSKEVRNCTVGVVGLGRIGRVAAQIFHGMGATVIGEDVFEIKGIEDYCTQVSLDEVLEKS 199 Query: 205 DVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAID 264 D++++H P ++ + MK G++L+N +RG +VD A+ +A+ S L G D Sbjct: 200 DIITIHAPYIKENGAVVTRDFLKKMKDGAILVNCARGQLVDTEAVIEAVESGKLGGYGCD 259 Query: 265 VFPTE-----PATNSDPFTSPLCE-----FDNVLLTPHIGGSTQEAQENIGLEVAGKLIK 314 V E +PL E + VL+TPH+G T EA +N+ L Sbjct: 260 VLDGEASVFGKDLEGQKLENPLFEKLVDLYPRVLITPHLGSYTDEAVKNMVEVSYQNLKD 319 Query: 315 YSDNGSTLSAV 325 ++ G + + Sbjct: 320 LAETGDCPNKI 330 >6ABI-A nrPDB Length = 358 Score = 256 bits (655), Expect = 1e-68, Method: Composition-based stats. Identities = 79/341 (23%), Positives = 136/341 (39%), Gaps = 19/341 (5%) Query: 5 SLEKDKIKFLLVEGVHQKALESLRAAGYT---NIEFHKGALDDEQLKESIRDAHFIGLRS 61 +LE K K + + + E + G + F K L +E + + + Sbjct: 21 TLEMQKTKIIFFD-IKDYDKEFFKKYGADYNFEMTFLKVRLTEET-ANLTKGYDVVCGFA 78 Query: 62 RTHLTEDVIN--AAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGE 119 ++ ++ I+ A + + C G N V L +R V P + ++AE +G Sbjct: 79 NDNINKETIDIMAENGIKLLAMRCAGFNNVSLKDVNER-FKVVRVPAYSPHAIAEYTVGL 137 Query: 120 LLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYF 179 +L + R + +A + G ++ + K GIIG G IG L + M V Sbjct: 138 ILAVNRKINKAYVRTREGNFSINGLMGIDLYEKTAGIIGTGKIGQILIKILRGFDMKVIA 197 Query: 180 YDIEN--KLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLIN 237 YD+ K+ + L +L SD++SL+ P TK M+ + + MK G +L+N Sbjct: 198 YDLFPNQKVADELGFEYVSLDELYANSDIISLNCPLTKDTKYMINRRSMLKMKDGVILVN 257 Query: 238 ASRGTVVDIPALCDALASKHLAGAAIDV---------FPTEPATNSDPFTSPLCEFDNVL 288 RG ++D L +AL K + A+DV D L F NVL Sbjct: 258 TGRGMLIDSADLVEALKDKKIGAVALDVYEEEENYFFEDKSTQVIEDDILGRLLSFYNVL 317 Query: 289 LTPHIGGSTQEAQENIGLEVAGKLIKYSDNGSTLSAVNFPE 329 +T H T+EA I + + + + ++ V + Sbjct: 318 ITSHQAYFTKEAVGAITVTTLNNIKDFVEGRPLVNEVPQNQ 358 >4S1V-D nrPDB Length = 332 Score = 254 bits (650), Expect = 4e-68, Method: Composition-based stats. Identities = 80/322 (24%), Positives = 142/322 (44%), Gaps = 18/322 (5%) Query: 1 MAKVSLEKDKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHF-IGL 59 M K+++ D + G++ A + L+ G+ F+ D+ L E ++ + + Sbjct: 1 MMKIAILDDYQNVV--RGLN--AFQCLQ--GHDVTVFNDSVSDETVLIERLKPFEALVLI 54 Query: 60 RSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGE 119 R RT +TE+++ L I +N +D+ + G+ V + + AEL Sbjct: 55 RERTPITENLLAHLPNLKLISQTGKVSNHIDVPLCERYGVTVLEGIG-SPVAPAELCWSL 113 Query: 120 LLLLLRGVPEANAKAHRGVWNKLAAGS--FEARGKKLGIIGYGHIGTQLGILAESLGMYV 177 +L R +P + H G W + G+ LGI G G IG ++ GM + Sbjct: 114 ILAASRHLPSYIEQLHAGHWQQNGGLGLGRTLSGRTLGIWGLGKIGQRIAQFGHVFGMPI 173 Query: 178 YFY----DIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGS 233 + + L LG ++ +DV+SLH+ N +T+ ++ +++ MKP S Sbjct: 174 LVWGSEASRQKALELGYQAAADK-AEFFAKADVLSLHLRLNDATRGIVTKQDLLAMKPDS 232 Query: 234 LLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHI 293 L +N SR +V+ AL + + + AA+DV+ EPA P PL NVL PH+ Sbjct: 233 LFVNTSRAELVESGALYSVMQANPMRQAAVDVYENEPAL---PNNEPLLSLPNVLCAPHL 289 Query: 294 GGSTQEAQENIGLEVAGKLIKY 315 G + + E ++K+ Sbjct: 290 GYVEKNSYEIYFQAAFENVVKF 311 >4PRK-A nrPDB Length = 336 Score = 254 bits (648), Expect = 7e-68, Method: Composition-based stats. Identities = 83/320 (25%), Positives = 148/320 (46%), Gaps = 17/320 (5%) Query: 21 QKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVINAAEKL---- 76 +K + + ++ +L E + + + D + L+ +L ++++ +KL Sbjct: 13 RKLVAATEKKFGCELKLIDESLSAENV-DQVADCDGVLLKPLGNLDDEIV--YKKLADYG 69 Query: 77 -VAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAH 135 +IG +GTN +D D A K + V N P + R++AE+ + + + L R + E A Sbjct: 70 IKSIGLRIVGTNTIDFDLAKKYHLTVTNVPVYSPRAIAEMAVTQAMYLNRKIGEFKANMD 129 Query: 136 RGVW-NKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQV 194 +G + N + S E K +G+IG GHIG+ + + ++G V YD+ + Sbjct: 130 KGDFTNPDSLISNEIYNKTIGLIGVGHIGSAVAQIFSAMGAKVLAYDVIYNPEVEPYLTY 189 Query: 195 QHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALA 254 +L +D++SLH P ST+NM+G K+ + MK ++LINA+RG +VD AL +AL Sbjct: 190 ADFDTVLKEADIISLHTPLLKSTENMIGKKQFAEMKNDAILINAARGELVDTAALIEALE 249 Query: 255 SKHLAGAAIDVFPTEPATNSDPFTSP--------LCEFDNVLLTPHIGGSTQEAQENIGL 306 +A A +D E + L NV++TPH T+ + N+ Sbjct: 250 KHEIAAAGLDTLAHESSYFFKKVDDAQIPADYKKLAAMPNVIVTPHSAYFTKTSVRNMIE 309 Query: 307 EVAGKLIKYSDNGSTLSAVN 326 I ++ V+ Sbjct: 310 ISLRDTIALANGERAHFVVS 329 >3WNV-A nrPDB Length = 330 Score = 245 bits (626), Expect = 2e-65, Method: Composition-based stats. Identities = 81/304 (26%), Positives = 137/304 (45%), Gaps = 9/304 (2%) Query: 24 LESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCF- 82 L+ G + + + + R I + ++I+A K V C Sbjct: 28 LKEFPEGGREKFLENCKSGQYDDVIAIYR--SNISTKHTGPFDRELISALPKSVKYICHN 85 Query: 83 CIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKL 142 G + +D+DAA + GI + + P + + A++ I ++ LR G W+ Sbjct: 86 GAGYDNIDVDAATEAGIAISSTPIAVNNATADVAIFLMIGALRQAYVPITAIRAGEWHGK 145 Query: 143 AAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPL-GNATQVQHLSDLL 201 + GK LGI+G G IG ++ A + GM + +++ P + + +LL Sbjct: 146 TTLGHDPNGKTLGILGMGGIGREVARRARAFGMNIIYHNRNKLPPELEDGAKYVSFDELL 205 Query: 202 NMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGA 261 SDV SL++ N ST++++G KE++ MK G +++N +RG ++D AL AL S +A Sbjct: 206 AQSDVFSLNLALNASTRHIIGEKELAKMKDGVVIVNTARGALIDEKALVRALESGKVASV 265 Query: 262 AIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDNGST 321 +DV+ EP L +L PHIG T E Q+ + L V L + G Sbjct: 266 GLDVYENEPQVEPG-----LLNNPRAMLLPHIGTMTYETQKEMELLVLNNLRSAIEKGEL 320 Query: 322 LSAV 325 L+ V Sbjct: 321 LTQV 324 >3GG9-A nrPDB Length = 352 Score = 245 bits (625), Expect = 3e-65, Method: Composition-based stats. Identities = 79/321 (24%), Positives = 129/321 (40%), Gaps = 27/321 (8%) Query: 32 YTNIEFHKGALDDEQLKESIRDAHF-IGLRSRTHLTEDVINAAEKLVAIGCFC-----IG 85 + F+ QL + D + +R RT +T +++ KL I G Sbjct: 27 HEVKVFNNTVKGVGQLAARVADVEALVLIRERTRVTRQLLDRLPKLKIISQTGRVSRDAG 86 Query: 86 TNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAG 145 +DL+A +G+ V + + AEL ++ R +P+ A G W + Sbjct: 87 -GHIDLEACTDKGVVVLEGKG-SPVAPAELTWALVMAAQRRIPQYVASLKHGAWQQSGLK 144 Query: 146 SFE----------ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIEN---KLPLGNAT 192 S +G+ LGI GYG IG + + GM V + EN + Sbjct: 145 STTMPPNFGIGRVLKGQTLGIFGYGKIGQLVAGYGRAFGMNVLVWGRENSKERARADGFA 204 Query: 193 QVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDA 252 + L SDV+S+H+ N T++++ +++ MKP +L +N SR +V+ + A Sbjct: 205 VAESKDALFEQSDVLSVHLRLNDETRSIITVADLTRMKPTALFVNTSRAELVEENGMVTA 264 Query: 253 LASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKL 312 L AAIDVF TEP L +N + TPHIG +E+ E + Sbjct: 265 LNRGRPGMAAIDVFETEPILQG----HTLLRMENCICTPHIGYVERESYEMYFGIAFQNI 320 Query: 313 IKYSDNGSTLSAVNFPEVSLP 333 + + +V P P Sbjct: 321 LDILQG--NVDSVANPTALAP 339 >4XKJ-A nrPDB Length = 335 Score = 241 bits (616), Expect = 3e-64, Method: Composition-based stats. Identities = 95/323 (29%), Positives = 154/323 (47%), Gaps = 13/323 (4%) Query: 21 QKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHL-TEDVINAAEK--LV 77 + A+ ++ ++ LD E + + I ++ R+H+ V +K L Sbjct: 13 EAAIREWEKKTGVQVDINRLELDAET-AQLTKGYDGIVIQQRSHISNPAVYETLQKNGLR 71 Query: 78 AIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRG 137 + G + +DL+ A++RG+ V N P + SVAEL + + + L+R +P +A+ Sbjct: 72 QLTSRTAGYDMIDLEQASERGLVVTNVPAYSPNSVAELALTQTMRLIRNLPLFDARGAEQ 131 Query: 138 VWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHL 197 + + E R +GIIG G IG + L ++LG V DI ++ L + Sbjct: 132 DFRWAGLMAREIRSLTVGIIGAGRIGGTVARLFKALGATVIANDIVERVELKDIVTYVSK 191 Query: 198 SDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKH 257 +LL +DVV+LHVP ST ++ A ++LMK ++LINASRG VVD AL AL +K Sbjct: 192 EELLQAADVVTLHVPLMDSTTQLIDADALALMKNDAVLINASRGPVVDTDALIAALQNKQ 251 Query: 258 LAGAAIDVFPTEPATNSDPF---------TSPLCEFDNVLLTPHIGGSTQEAQENIGLEV 308 +AGAA+D E + L NVL+TPHIG T +A +N+ Sbjct: 252 IAGAALDTLNGEEHFFNQDLCGKELPSEQLKVLRTLPNVLITPHIGFYTNKAVQNMVEIS 311 Query: 309 AGKLIKYSDNGSTLSAVNFPEVS 331 ++ G++ +N V Sbjct: 312 LNDVLAILKTGTSEHQLNKVAVE 334 >5DT9-A nrPDB Length = 387 Score = 236 bits (601), Expect = 2e-62, Method: Composition-based stats. Identities = 83/328 (25%), Positives = 132/328 (40%), Gaps = 36/328 (10%) Query: 11 IKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVI 70 +K L+ E + A G ++ + L + L D + +RS T + + ++ Sbjct: 7 MKILIDENM-PYAQALFSQLGEVILKPGR-TLTADDLI----DVDALMIRSVTKVNDALL 60 Query: 71 NAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEA 130 A +L +G G + VD +RGI AP N VAE V L++L + Sbjct: 61 AKANRLKFVGTATAGMDHVDQALLRERGIFFTAAPGCNKVGVAEYVFSVLMVLAQQ---- 116 Query: 131 NAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGN 190 F K +GIIG G +G+ L +GM V D K G+ Sbjct: 117 --------------QGFSVFDKTVGIIGAGQVGSYLAKCLSGIGMKVLLND-PPKQAQGD 161 Query: 191 ATQVQHLSDLLNMSDVVSLHVPENP----STKNMMGAKEISLMKPGSLLINASRGTVVDI 246 + L LL +DV++LH P T +++ A + ++ +LINA+RG VVD Sbjct: 162 EREFTELETLLKQADVITLHTPITRGGEWPTHHLIDAAILEQLRSDQILINAARGPVVDN 221 Query: 247 PALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGL 306 AL L A +DVF EP + + PL F TPHI G E + Sbjct: 222 AALKARLQQGDGFTAVLDVFEFEPQVDMELL--PLLAF----ATPHIAGYGLEGKARGTT 275 Query: 307 EVAGKLIKYSDNGSTLSAVN-FPEVSLP 333 + ++ + + + P+ +P Sbjct: 276 MIFNSYCEFLGSAHCANPASLLPKAPVP 303 >3HG7-A nrPDB Length = 324 Score = 233 bits (595), Expect = 9e-62, Method: Composition-based stats. Identities = 78/326 (23%), Positives = 131/326 (40%), Gaps = 16/326 (4%) Query: 4 VSLEKDKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRT 63 +SL + + L + H + L + I D E+L I +AH + Sbjct: 1 MSLSQRTLLLLSQDNAHYERLLKAAHLPHLRILRADNQSDAEKL---IGEAHILMAEPAR 57 Query: 64 HLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLL 123 + ++ A KL G + V LDA +R + N ++E V G LL L Sbjct: 58 A--KPLLAKANKLSWFQSTYAGVD-VLLDARCRRDYQLTNVRGIFGPLMSEYVFGHLLSL 114 Query: 124 LRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIE 183 +R +P + + +W +G+ L I+G G IG + + GM V Sbjct: 115 MRQLPLYREQQKQRLWQSHPYQG--LKGRTLLILGTGSIGQHIAHTGKHFGMKVLGVSRS 172 Query: 184 NKLPLG--NATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRG 241 + G Q+ L+ +L +DV+ +P T ++ A KPG++L N RG Sbjct: 173 GRERAGFDQVYQLPALNKMLAQADVIVSVLPATRETHHLFTASRFEHCKPGAILFNVGRG 232 Query: 242 TVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQ 301 ++ L AL + L A +DVF EP P SPL N+++TPH + Sbjct: 233 NAINEGDLLTALRTGKLGMAVLDVFEQEPL----PADSPLWGQPNLIITPHNSAYSFP-- 286 Query: 302 ENIGLEVAGKLIKYSDNGSTLSAVNF 327 +++ I++ D ++F Sbjct: 287 DDVAQIFVRNYIRFIDGQPLDGKIDF 312 >2W2L-A nrPDB Length = 348 Score = 223 bits (568), Expect = 1e-58, Method: Composition-based stats. Identities = 83/338 (24%), Positives = 135/338 (39%), Gaps = 31/338 (9%) Query: 10 KIKFLLVEGVHQKALESLRAAGYTNIEFHKGAL------DDEQLKESIRDAHFIGLRSRT 63 + + LL+ G + L+ L + E L ++ D I + Sbjct: 3 RPRVLLL-GDPARHLDDLWSDFQQKFEVIPANLTTHDGFKQALREKRYGDFEAIIKLAVE 61 Query: 64 HLTE------DVINAAEK-LVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELV 116 + TE D+I+ L G + +DLDA +RG+ N+ + + ++L Sbjct: 62 NGTESYPWNADLISHLPSSLKVFAAAGAGFDWLDLDALNERGVAFANSRGAGDTATSDLA 121 Query: 117 IGELLLLLRGVPEANAKAHRGVWN-------KLAAGSFEARGKKLGIIGYGHIGTQLGIL 169 + +L + R + A G ++ + RG LG +G G I ++ Sbjct: 122 LYLILSVFRLASYSERAARTGDPETFNRVHLEIGKSAHNPRGHVLGAVGLGAIQKEIARK 181 Query: 170 A-ESLGMYVYFYDIENKLPLGN----ATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAK 224 A LGM + +YD+ A +V L +L SD VS+ VP T +++ Sbjct: 182 AVHGLGMKLVYYDVAPADAETEKALGAERVDSLEELARRSDCVSVSVPYMKLTHHLIDEA 241 Query: 225 EISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEF 284 + MKPGS ++N +RG V+ AL AL S L A +DV EP + + L E Sbjct: 242 FFAAMKPGSRIVNTARGPVISQDALIAALKSGKLLSAGLDVHEFEPQVSKE-----LIEM 296 Query: 285 DNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDNGSTL 322 +V LT HIGG E + ++ G L Sbjct: 297 KHVTLTTHIGGVAIETFHEFERLTMTNIDRFLLQGKPL 334 >3EVT-A nrPDB Length = 324 Score = 215 bits (549), Expect = 2e-56, Method: Composition-based stats. Identities = 70/320 (21%), Positives = 126/320 (39%), Gaps = 16/320 (5%) Query: 13 FLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLR-SRTHLTEDVIN 71 L+ + + L+ L+ + + + D I + L + ++ Sbjct: 4 VLMAQATKPEQLQQLQ-------TTYPDWTFKDAAAVTAADYDQIEVMYGNHPLLKTILA 56 Query: 72 A-AEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEA 130 +L + G + + L A G+ V N + +++E V+ +L ++RG A Sbjct: 57 RPTNQLKFVQVISAGVDYLPLKALQAAGVVVANTSGIHADAISESVLAAMLSVVRGYHAA 116 Query: 131 NAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGN 190 L + G++L I G G IG L A +LGM+V + Sbjct: 117 WLNQRGARQWALPMTTSTLTGQQLLIYGTGQIGQSLAAKASALGMHVIGVNTTGHPADHF 176 Query: 191 ATQVQHLSDLLNMS--DVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPA 248 V + ++ + + +P P+T ++ + K +LIN RG VD A Sbjct: 177 HETVAFTATADALATANFIVNALPLTPTTHHLFSTELFQQTKQQPMLINIGRGPAVDTTA 236 Query: 249 LCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEV 308 L AL L+ AA+DV EP P PL + D+VL+TPHI G + + Sbjct: 237 LMTALDHHQLSMAALDVTEPEPL----PTDHPLWQRDDVLITPHISGQIAHFRATVFPIF 292 Query: 309 AGKLIKYSDNGSTL-SAVNF 327 A ++ +G+ + + V+ Sbjct: 293 AANFAQFVKDGTLVRNQVDL 312 >3OET-A nrPDB Length = 381 Score = 215 bits (548), Expect = 3e-56, Method: Composition-based stats. Identities = 86/345 (24%), Positives = 138/345 (40%), Gaps = 41/345 (11%) Query: 9 DKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTED 68 + +K L+ E + A E G K E + A + +RS T + E Sbjct: 2 NAMKILVDENM-PYARELFSRLGEV-----KAVPGRPIPVEELNHADALMVRSVTKVNES 55 Query: 69 VINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVP 128 +++ + +G GT+ VD + GI AP N +V E V LL+L Sbjct: 56 LLSGTP-INFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSALLMLAERD- 113 Query: 129 EANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPL 188 F R + +GI+G G++G++L E+LG+ D + Sbjct: 114 -----------------GFSLRDRTIGIVGVGNVGSRLQTRLEALGIRTLLCD-PPRAAR 155 Query: 189 GNATQVQHLSDLLNMSDVVSLHVPENPS----TKNMMGAKEISLMKPGSLLINASRGTVV 244 G+ + L +L+ +DV++ H P T ++ I +KPG++LINA RG VV Sbjct: 156 GDEGDFRTLDELVQEADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGPVV 215 Query: 245 DIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENI 304 D AL L + +DV+ EP D + L D + T HI G T E + Sbjct: 216 DNAALLARLNAGQPLSVVLDVWEGEP----DLNVALLEAVD--IGTSHIAGYTLEGKARG 269 Query: 305 GLEVAGKLIKYSDNGSTLSAVNFPEVSLP-LHGGRRLMHIHENRP 348 +V + ++ E LP GR +H ++P Sbjct: 270 TTQVFEAYSAFIGREQRVAL----ETLLPAPEFGRITLHGPLDQP 310 >5MH6-A nrPDB Length = 308 Score = 212 bits (540), Expect = 2e-55, Method: Composition-based stats. Identities = 65/250 (26%), Positives = 110/250 (44%), Gaps = 7/250 (2%) Query: 79 IGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGV 138 + C G ++ + + G + N+ + +V E V G +L R + H Sbjct: 62 VHCIRAGYDEFPVGVYEEAGTYLTNSTGIHGTTVGETVAGYMLTFARRLHAYRDAQHDHA 121 Query: 139 WN-KLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQV--Q 195 W+ F G+++ ++G G +G + A +LGM V +T Sbjct: 122 WDLPRYEEPFTLAGERVCVVGLGTLGRGVVDRAAALGMEVVGVRRSGDPVDNVSTVYTPD 181 Query: 196 HLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALAS 255 L + + + V L P T+ M+ A E M+ + L+N +RG VV L AL S Sbjct: 182 RLHEAIADARFVVLATPLTDETEGMVAAPEFETMREDASLVNVARGPVVVESDLVAALDS 241 Query: 256 KHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKY 315 +AGAA+DVF EP P SPL +F++VL+TPH+ +T + E++ + + K Sbjct: 242 GDIAGAALDVFSEEPL----PEDSPLWDFEDVLITPHVSAATSKYHEDVAALIRENIEKI 297 Query: 316 SDNGSTLSAV 325 + + V Sbjct: 298 ATGDELTNRV 307 >4N18-A nrPDB Length = 332 Score = 203 bits (516), Expect = 1e-52, Method: Composition-based stats. Identities = 60/264 (22%), Positives = 97/264 (36%), Gaps = 12/264 (4%) Query: 66 TEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFS-NTRSVAELVIGELLLLL 124 +++ + L I G + + A IP+ + E + +L Sbjct: 73 DPQLLSRSPGLKLIQAASAGVDHLP-PALFASEIPLCRVIDEDFRHGMFEYALWSVLWFQ 131 Query: 125 RGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIEN 184 R A A W + A +GI+G G IG + LG V + Sbjct: 132 RHFDRALAHQRTQTWKLYPQRA--AADFHIGIMGLGEIGGYIADQLARLGYRVSGWSRSE 189 Query: 185 KLPLGNATQV--QHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGT 242 K G + L L D + +P T+ ++ A + + G++LIN RG Sbjct: 190 KQLAGVTCYRGEEALDHFLGSLDGLINLLPLTAQTRGILAAPLFNRLPAGAVLINCGRGE 249 Query: 243 VVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQE 302 + + AL S LAGA +DVFP EP P PL V++TPH+ + E Sbjct: 250 HMVNDDVLAALESGQLAGAVLDVFPQEPL----PADDPLWRHPQVVITPHMASAAPA--E 303 Query: 303 NIGLEVAGKLIKYSDNGSTLSAVN 326 I ++ + + + VN Sbjct: 304 VIARQLLENIQRQRRGLPLKNLVN 327 >5TSD-A nrPDB Length = 322 Score = 200 bits (508), Expect = 1e-51, Method: Composition-based stats. Identities = 70/323 (21%), Positives = 125/323 (38%), Gaps = 21/323 (6%) Query: 10 KIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDV 69 + L+ + + ++ + + + +G+++ RD D+ Sbjct: 7 RPPVLVDIKFNPEGVDRVLKTAFAD----RGSINLADPANRERDFSETEYALLWKPDADL 62 Query: 70 INAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFN-APFSNTRSVAELVIGELLLLLRGVP 128 A L I G + + + A IP+ S T ++E V+ + L+ LRG Sbjct: 63 FRRAPNLKVIFSGGAGVDHI-IGMAGLPDIPIVRFVDRSLTTRMSEWVVMQCLMHLRGQY 121 Query: 129 EANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPL 188 ++ R W KL A EA +G++G G +G + +G V + K Sbjct: 122 GHDSHQRRREWAKLIAP--EAAEVTVGVMGLGILGQDAVAKLKVMGFNVIGWSRTRKTIE 179 Query: 189 GNAT-QVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGS-----LLINASRGT 242 G T L L +D++ +P P T ++ ++ + INA RG Sbjct: 180 GVETFDAGELDRFLAKTDILVGLLPLTPETTGFYDSELFKKLRRDGALGQPVFINAGRGK 239 Query: 243 VVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQE 302 + A+ L GA++DVF EP SPL E +NV +TPH ++E Sbjct: 240 SQIETDIVSAVREGTLGGASLDVFEVEPLAT----DSPLWELENVFITPHDAAVSEE--N 293 Query: 303 NIGLEVAGKLIKYSDNGSTLSAV 325 + V ++ ++ + G L V Sbjct: 294 ALFRHVEMQIARF-ERGEPLQFV 315 >4WEQ-A nrPDB Length = 341 Score = 198 bits (503), Expect = 5e-51, Method: Composition-based stats. Identities = 67/297 (22%), Positives = 114/297 (38%), Gaps = 23/297 (7%) Query: 39 KGALDDEQLKESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRG 98 + +D RD I D+ + A L + G + V G Sbjct: 51 REVIDLADPAHQERDLSGIDYAVVWKSAPDLFSRAPDLKVVFSGGAGVDHV----LTLPG 106 Query: 99 IP----VFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKL 154 +P V + T ++E V+ + LL LR A A + W L+ EA + Sbjct: 107 LPDVPLVRFVDRTLTTRMSEWVMMQCLLHLRQHRAYEALAKKHEWRDLSQP--EAADVTV 164 Query: 155 GIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQ-VQHLSDLLNMSDVVSLHVPE 213 GI+G G +G ++G V + ++ G T L L +D + +P Sbjct: 165 GIMGMGVLGQDAARKLAAMGFKVIGWSRSKRVIEGVETYDAAGLDAFLGRTDFLVGLLPL 224 Query: 214 NPSTKNMMGAKEISLMKPGS-----LLINASRGTVVDIPALCDALASKHLAGAAIDVFPT 268 P T+ + A + + + INA RG + + L S L GA++DVF Sbjct: 225 TPDTRGIFNAALFAKLSRNGPFGAPVFINAGRGGSQVEADILECLDSGVLGGASLDVFER 284 Query: 269 EPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDNGSTLSAV 325 EP + F + NV +TPH+ S+ + + V ++ ++ ++G L V Sbjct: 285 EPLSPESRF----WDMPNVYVTPHVAASSD--VRALFVHVEHQIARF-ESGLPLEHV 334 >4XA8-A nrPDB Length = 320 Score = 195 bits (496), Expect = 3e-50, Method: Composition-based stats. Identities = 66/265 (24%), Positives = 109/265 (41%), Gaps = 20/265 (7%) Query: 69 VINAAEKLVAIGCFCIGTNQV----DLDAAAKRGIPVFNAPFSN-TRSVAELVIGELLLL 123 L + G + + DL +PV N ++ +A V+ +L Sbjct: 64 FFARFPNLKLVINLGAGVDALVARDDLP-----DVPVTRLSDPNMSQMMASFVLFCVLRH 118 Query: 124 LRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIE 183 R +P G W+ + A ++G++G G +G + G V + Sbjct: 119 ARDIPTFERAQREGRWHYV--HPRTAAEIRVGVLGLGDLGAAAALELARHGFDVRGWSRT 176 Query: 184 NKLPLGNATQV--QHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRG 241 K G + + L L S++V + +P P T+ +M A+ ++ + G+ IN +RG Sbjct: 177 PKALEGVSCFHGLEALPGFLAGSEIVVVMLPLTPETRGLMNAERLAHLPRGAKFINVARG 236 Query: 242 TVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQ 301 VVD AL AL S H+A A +DVF EP P SPL DNVL+TPH+ Sbjct: 237 PVVDEAALIAALRSGHIAEATLDVFEVEPL----PVGSPLWAMDNVLVTPHLASIAIP-- 290 Query: 302 ENIGLEVAGKLIKYSDNGSTLSAVN 326 ++ + + L+ V+ Sbjct: 291 RTAAPQIVENIRRIEAGEPVLNQVD 315 >5C5I-A nrPDB Length = 316 Score = 191 bits (485), Expect = 5e-49, Method: Composition-based stats. Identities = 58/279 (20%), Positives = 105/279 (37%), Gaps = 15/279 (5%) Query: 52 RDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFN-APFSNTR 110 + + + + LV I G ++ + P+ R Sbjct: 46 AEVDIAIVANPDPAD---LAELPNLVWIHSLWAGVERL-VAELGHLARPIVRLVDPELAR 101 Query: 111 SVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILA 170 ++AE + L R +P A+ VW L E +G++G G +G + Sbjct: 102 TMAEAALAWTYYLFRDMPAYAAQQRARVWKGLPYKRPERT--TVGVLGLGELGAAAALRL 159 Query: 171 ESLGMYVYFYDIENKLPLGNATQV--QHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISL 228 G V+ + K G + L +L +++ +P T+ ++ A+ ++ Sbjct: 160 RDAGFDVHGWSRSPKEIAGVTCHAGEETLERMLGQVEILVCLLPLTGETRGLLDARRLAC 219 Query: 229 MKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVL 288 + G+ ++N +RG ++D AL +AL S + A +DVF EP P SP V Sbjct: 220 LPEGAQIVNFARGPILDSAALIEALDSGRIGHAVLDVFEVEPL----PEASPFWGHPKVT 275 Query: 289 LTPHIGGSTQEAQENIGLEVAGKLIKYSDNGSTLSAVNF 327 + PHI +T E V + Y G +V+ Sbjct: 276 VLPHISAATDP--ETASAIVGAHVADYRATGRIPPSVDL 312 >1QP8-A nrPDB Length = 303 Score = 190 bits (484), Expect = 8e-49, Method: Composition-based stats. Identities = 54/276 (19%), Positives = 107/276 (38%), Gaps = 12/276 (4%) Query: 50 SIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNT 109 + + + +T + + +L I G + + ++ + V SN Sbjct: 28 DLGNVEAALVS---RITAEELAKMPRLKFIQVVTAGLDHLPWESIPPH-VTVAGNAGSNA 83 Query: 110 RSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGIL 169 +VAE + LL + + + K RG + + +G+K+ ++G G IGT++G + Sbjct: 84 DAVAEFALALLLAPYKRIIQYGEKMKRGDYGRDVEIPL-IQGEKVAVLGLGEIGTRVGKI 142 Query: 170 AESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLM 229 +LG V + K G L + L + +P N T+ ++ + ++LM Sbjct: 143 LAALGAQVRGFSRTPK--EGPWRFTNSLEEALREARAAVCALPLNKHTRGLVKYQHLALM 200 Query: 230 KPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLL 289 ++ +N R V+D + L + A DV+ N + NV+ Sbjct: 201 AEDAVFVNVGRAEVLDRDGVLRILKERPQFIFASDVWWG---RNDFAKDAEFFSLPNVVA 257 Query: 290 TPHIGG--STQEAQENIGLEVAGKLIKYSDNGSTLS 323 TP + G + + +E LI Y+ G + Sbjct: 258 TPWVAGGYGNERVWRQMVMEAVRNLITYATGGRPRN 293 >3KBO-A nrPDB Length = 315 Score = 189 bits (480), Expect = 2e-48, Method: Composition-based stats. Identities = 61/261 (23%), Positives = 111/261 (42%), Gaps = 17/261 (6%) Query: 72 AAEKLVAIGCFCIGTNQV--DLDAAAK---RGIPVFNAPF-SNTRSVAELVIGELLLLLR 125 A +L A+ G + + L+A + IP+F + E + ++L R Sbjct: 56 AGRRLKAVFVLGAGVDAILSKLNAHPEMLDASIPLFRLEDTGMGLQMQEYAVSQVLHWFR 115 Query: 126 GVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENK 185 + A ++ +W L + E +GI+G G +G ++ ++ G + + K Sbjct: 116 RFDDYQALKNQALWKPLPEYTRE--EFSVGIMGAGVLGAKVAESLQAWGFPLRCWSRSRK 173 Query: 186 LPLGNATQV--QHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTV 243 G + V + L LN + V+ +P T ++ ++ + + G+ ++N +RG Sbjct: 174 SWPGVESYVGREELRAFLNQTRVLINLLPNTAQTVGIINSELLDQLPDGAYVLNLARGVH 233 Query: 244 VDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQEN 303 V L AL S L GA +DVF EP P SPL V +TPHI T+ A+ Sbjct: 234 VQEADLLAALDSGKLKGAMLDVFSQEPL----PQESPLWRHPRVAMTPHIAAVTRPAE-- 287 Query: 304 IGLEVAGKLIKYSDNGSTLSA 324 ++ + I + G ++ Sbjct: 288 -AIDYISRTITQLEKGEPVTG 307 >2O4C-A nrPDB Length = 380 Score = 188 bits (477), Expect = 5e-48, Method: Composition-based stats. Identities = 68/272 (25%), Positives = 117/272 (43%), Gaps = 30/272 (11%) Query: 49 ESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSN 108 ++ + + +RS T ++ + + + +G IGT+ +DLD A+ GI +AP N Sbjct: 33 AALAEVDVLLVRSVTEVSRAALAGSP-VRFVGTCTIGTDHLDLDYFAEAGIAWSSAPGCN 91 Query: 109 TRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGI 168 R V + V+G LL + + + G++G G +G +L Sbjct: 92 ARGVVDYVLGCLLAMA------------------EVRGADLAERTYGVVGAGQVGGRLVE 133 Query: 169 LAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPS----TKNMMGAK 224 + LG V D + + L LL +DV+SLH P N T++++ Sbjct: 134 VLRGLGWKVLVCD-PPRQAREPDGEFVSLERLLAEADVISLHTPLNRDGEHPTRHLLDEP 192 Query: 225 EISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEF 284 ++ ++PG+ L+NASRG VVD AL L A+DV+ EP + + L Sbjct: 193 RLAALRPGTWLVNASRGAVVDNQALRRLLEGGADLEVALDVWEGEPQADPELAARCL--- 249 Query: 285 DNVLLTPHIGGSTQEAQENIGLEVAGKLIKYS 316 + TPHI G + E + ++ + Sbjct: 250 ---IATPHIAGYSLEGKLRGTAQIYQAYCAWR 278 >4HY3-A nrPDB Length = 365 Score = 182 bits (463), Expect = 2e-46, Method: Composition-based stats. Identities = 68/265 (25%), Positives = 109/265 (41%), Gaps = 12/265 (4%) Query: 64 HLTEDVINAAEKLVAIGCFCIGT-NQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLL 122 L+ + + L +I N + + +RGI V VAE+ +G L Sbjct: 85 PLSAETLARMPALRSILNVESNLLNNMPYEVLFQRGIHVVTTGQVFAEPVAEIGLGFALA 144 Query: 123 LLRGVPEANAKAHRGVWNKLAAGSFEAR---GKKLGIIGYGHIGTQLGILAESLGMYVYF 179 L RG+ +A+ G G+ AR G ++GI+G+G +G L + + Sbjct: 145 LARGIVDADIAFQEGTELWGGEGNASARLIAGSEIGIVGFGDLGKALRRVLSGFRARIRV 204 Query: 180 YDI--ENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLIN 237 +D + N + L D+L SD + + K +GA+ S M+ G+ I Sbjct: 205 FDPWLPRSMLEENGVEPASLEDVLTKSDFIFVVAAVTSENKRFLGAEAFSSMRRGAAFIL 264 Query: 238 ASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGST 297 SR VVD AL A++S H+ AA DV+P EP P P+ + + H G+ Sbjct: 265 LSRADVVDFDALMAAVSSGHIV-AASDVYPEEPL----PLDHPVRSLKGFIRSAHRAGAL 319 Query: 298 QEAQENIGLEVAGKLIKYSDNGSTL 322 A + +G V + D G Sbjct: 320 DSAFKKMGDMVLEDM-DLMDRGLPP 343 >3GVX-A nrPDB Length = 290 Score = 178 bits (451), Expect = 4e-45, Method: Composition-based stats. Identities = 56/260 (21%), Positives = 108/260 (41%), Gaps = 12/260 (4%) Query: 61 SRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGEL 120 + + +D ++ I G + +D++ + + NA + SVAE L Sbjct: 35 AEAQVIKDRYVLGKRTKMIQAISAGVDHIDVNGIPENVVLCSNAGAYS-ISVAEHAFALL 93 Query: 121 LLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFY 180 L + + E N G++ + + GK LGI+GYG IG ++ LA++ GM V Y Sbjct: 94 LAHAKNILENNELMKAGIFRQSP--TTLLYGKALGILGYGGIGRRVAHLAKAFGMRVIAY 151 Query: 181 DIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASR 240 + + + +DL SD V + +P T+ M+ ++ ++ + ++N +R Sbjct: 152 TRSS-VDQNVDVISESPADLFRQSDFVLIAIPLTDKTRGMVNSRLLANARKNLTIVNVAR 210 Query: 241 GTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEA 300 VV P + L + DV+ EP N +L+PH+ G Sbjct: 211 ADVVSKPDMIGFLKERSDVWYLSDVWWNEPEITE-------TNLRNAILSPHVAGGMSGE 263 Query: 301 QENIGLEVA-GKLIKYSDNG 319 +I +++A + + + Sbjct: 264 IMDIAIQLAFENVRNFFEGE 283 >5JXW-A nrPDB Length = 498 Score = 56.9 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 39/94 (41%), Gaps = 7/94 (7%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLG---NATQVQHLSDLLNMSD 205 GKK+ ++GYG +G +G V +I+ L QV L D+++ +D Sbjct: 269 LAGKKIVVLGYGEVGKGCAQGLSGVGARVIVTEIDPICALQASMEGYQVSVLEDVVSEAD 328 Query: 206 VVSLHVPENPSTKNMMGAKEISLMKPGSLLINAS 239 + K+++ + + MK + + N Sbjct: 329 IFITAT----GNKDVITVEHMRKMKENAYIANIG 358 >3H9U-A nrPDB Length = 436 Score = 55.7 bits (133), Expect = 4e-08, Method: Composition-based stats. Identities = 33/186 (17%), Positives = 62/186 (33%), Gaps = 31/186 (16%) Query: 65 LTEDVINAAEKL--VAIGCF---CIGTNQVDLDAAAKRG---IPVFNAPFSNTRSVAELV 116 LT V++ ++L G G L +RG IP N S T+S + + Sbjct: 133 LTNYVLDECKELDGKIYGVSEETTTGVKN--LYKRLQRGKLTIPAMNVNDSVTKSKFDNL 190 Query: 117 IGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMY 176 G L+ G+ A GK + GYG +G G Sbjct: 191 YGCRESLVDGIKRATDVM--------------IAGKTACVCGYGDVGKGCAAALRGFGAR 236 Query: 177 VYFYDIENKLPLG---NATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGS 233 V +++ L QV + D++ + + +++ ++ M+ + Sbjct: 237 VVVTEVDPINALQAAMEGYQVLLVEDVVEEAHIFVT----TTGNDDIITSEHFPRMRDDA 292 Query: 234 LLINAS 239 ++ N Sbjct: 293 IVCNIG 298 >6GBN-A nrPDB Length = 438 Score = 54.2 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 17/94 (18%), Positives = 35/94 (37%), Gaps = 7/94 (7%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIEN---KLPLGNATQVQHLSDLLNMSD 205 GK + GYG +G G V +I+ + +V+ ++D + +D Sbjct: 217 MAGKVAVVAGYGDVGKGSAASLRGAGARVIVTEIDPICALQAAMDGYEVKKMADAVKRAD 276 Query: 206 VVSLHVPENPSTKNMMGAKEISLMKPGSLLINAS 239 +V KN++ + M+ ++ N Sbjct: 277 IVVTAT----GNKNIITGEHFKAMRDKVIVCNIG 306 >3G1U-A nrPDB Length = 437 Score = 53.0 bits (126), Expect = 2e-07, Method: Composition-based stats. Identities = 14/94 (14%), Positives = 33/94 (35%), Gaps = 7/94 (7%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLG---NATQVQHLSDLLNMSD 205 GK + GYG +G + G V +++ L QV + D++ + Sbjct: 210 IAGKTCCVCGYGDVGKGCAAALRAFGARVVVTEVDPINALQASMEGYQVALVEDVMADAH 269 Query: 206 VVSLHVPENPSTKNMMGAKEISLMKPGSLLINAS 239 + +++ + M+ +++ N Sbjct: 270 IFVT----TTGNDDIITSDHFPHMRDDAIVCNIG 299 >2ZJ1-A nrPDB Length = 495 Score = 51.5 bits (122), Expect = 7e-07, Method: Composition-based stats. Identities = 50/235 (21%), Positives = 81/235 (34%), Gaps = 33/235 (14%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLG---NATQVQHLSDLLNMSD 205 GKK+ I GYG +G + G V +I+ L V + + + +D Sbjct: 273 IGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAMMEGFDVVTVEEAIGDAD 332 Query: 206 VVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAA--- 262 +V K+++ + I MK ++L N D L +GA Sbjct: 333 IVVTAT----GNKDIIMLEHIKAMKDHAILGNIG---HFDNEIDMAGLER---SGATRVN 382 Query: 263 ----IDVFPTEPATNS--DPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYS 316 +D++ S L N T H + N + ++ ++ Sbjct: 383 VKPQVDLWTFGDTGRSIIVLSEGRLLNLGN--ATGHPSFVMSNSFAN---QTIAQIELWT 437 Query: 317 DNGSTLSAVNFPEVSLPLHGGRRLMHIH-ENRPGVLTALNKIFAEQ-GVNIAAQY 369 N + V LP H ++ IH E G LT L K AE GV++ Y Sbjct: 438 KNDEYDNEV----YRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPY 488 >3D64-A nrPDB Length = 494 Score = 50.3 bits (119), Expect = 1e-06, Method: Composition-based stats. Identities = 15/94 (15%), Positives = 33/94 (35%), Gaps = 7/94 (7%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLG---NATQVQHLSDLLNMSD 205 GK + GYG +G LG V+ +I+ L +V + + +D Sbjct: 275 IAGKIAVVAGYGDVGKGCAQSLRGLGATVWVTEIDPICALQAAMEGYRVVTMEYAADKAD 334 Query: 206 VVSLHVPENPSTKNMMGAKEISLMKPGSLLINAS 239 + +++ + M+ +++ N Sbjct: 335 IFVTAT----GNYHVINHDHMKAMRHNAIVCNIG 364 >3OND-A nrPDB Length = 488 Score = 50.0 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 36/94 (38%), Gaps = 7/94 (7%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLG---NATQVQHLSDLLNMSD 205 GK + GYG +G + G V +I+ L QV L D+++ +D Sbjct: 263 IAGKVAVVAGYGDVGKGCAAALKQAGARVIVTEIDPICALQATMEGLQVLTLEDVVSEAD 322 Query: 206 VVSLHVPENPSTKNMMGAKEISLMKPGSLLINAS 239 + K+++ + MK +++ N Sbjct: 323 IFVT----TTGNKDIIMLDHMKKMKNNAIVCNIG 352 >6JCV-A nrPDB Length = 333 Score = 48.8 bits (115), Expect = 4e-06, Method: Composition-based stats. Identities = 18/67 (26%), Positives = 30/67 (44%), Gaps = 3/67 (4%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVY---FYDIENKLPLGNATQVQHLSDLLNMSD 205 +GK +G+IGYG+ G + G+ V D +L +V + + + SD Sbjct: 13 LKGKTIGVIGYGNQGRVQATIMRENGLNVIVGNVKDKYYELAKKEGFEVYEIDEAVRRSD 72 Query: 206 VVSLHVP 212 V L +P Sbjct: 73 VALLLIP 79 >3NJ4-A nrPDB Length = 435 Score = 48.4 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 15/97 (15%), Positives = 30/97 (30%), Gaps = 13/97 (13%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLG---NATQVQHLSDLLNMSD 205 GK + GYG +G G V +I+ L +V + + + Sbjct: 214 IAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGN 273 Query: 206 VVSLHVPENPSTKNMMG---AKEISLMKPGSLLINAS 239 + +T + + MK +++ N Sbjct: 274 IFV-------TTTGCIDIILGRHFEQMKDDAIVCNIG 303 >6APH-A nrPDB Length = 445 Score = 48.4 bits (114), Expect = 6e-06, Method: Composition-based stats. Identities = 14/94 (14%), Positives = 35/94 (37%), Gaps = 7/94 (7%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIEN---KLPLGNATQVQHLSDLLNMSD 205 GK++ + G+G +G G V +I+ +V+ L +++ +D Sbjct: 224 LAGKRVVVCGFGDVGKGTAASFRGAGSIVTVTEIDPICALQAAMEGYEVKQLDTVVDNAD 283 Query: 206 VVSLHVPENPSTKNMMGAKEISLMKPGSLLINAS 239 ++ ++ + MK +++ N Sbjct: 284 IIIT----TTGNFGIVRGEHFEKMKDKTIVCNIG 313 >3X2F-A nrPDB Length = 411 Score = 48.0 bits (113), Expect = 7e-06, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 40/94 (42%), Gaps = 7/94 (7%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLG---NATQVQHLSDLLNMSD 205 GK + + GYG G + + A LG V +++ + + V + + + ++D Sbjct: 195 VAGKNVVVAGYGWCGRGIALRAAGLGARVIVTEVDPVKAVEAIMDGFTVMPMKEAVKIAD 254 Query: 206 VVSLHVPENPSTKNMMGAKEISLMKPGSLLINAS 239 V ++ ++I +K G++L NA Sbjct: 255 FVITASGNTD----VLSKEDILSLKDGAVLANAG 284 >3N58-A nrPDB Length = 464 Score = 47.6 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 21/110 (19%), Positives = 38/110 (34%), Gaps = 10/110 (9%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLG---NATQVQHLSDLLNMSD 205 GK + GYG +G G V +++ L + +V L D + +D Sbjct: 245 MAGKVAVVCGYGDVGKGSAQSLAGAGARVKVTEVDPICALQAAMDGFEVVTLDDAASTAD 304 Query: 206 VVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALAS 255 +V K+++ + MK ++ N D AL + Sbjct: 305 IVVT----TTGNKDVITIDHMRKMKDMCIVGNIG---HFDNEIQVAALRN 347 >5M65-A nrPDB Length = 479 Score = 46.5 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 17/110 (15%), Positives = 37/110 (33%), Gaps = 10/110 (9%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLG---NATQVQHLSDLLNMSD 205 GK + G+G +G G V +++ L +V + D +D Sbjct: 258 LSGKVAMVAGFGDVGKGSAASLRQAGCRVMVSEVDPICALQAAMEGYEVVTMEDAAPRAD 317 Query: 206 VVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALAS 255 + K+++ + + MK +++ N D +L + Sbjct: 318 IFVTAT----GNKDIITIEHMRAMKDRAIVCNIG---HFDNEIQIASLRN 360 >1V8B-A nrPDB Length = 479 Score = 46.1 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 20/99 (20%), Positives = 38/99 (38%), Gaps = 7/99 (7%) Query: 144 AGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIEN---KLPLGNATQVQHLSDL 200 A F GK + I GYG +G + LG VY +I+ + V L ++ Sbjct: 250 ATDFLISGKIVVICGYGDVGKGCASSMKGLGARVYITEIDPICAIQAVMEGFNVVTLDEI 309 Query: 201 LNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINAS 239 ++ D +++ + + MK +++ N Sbjct: 310 VDKGDFFITCT----GNVDVIKLEHLLKMKNNAVVGNIG 344 >5U5G-A nrPDB Length = 295 Score = 45.3 bits (106), Expect = 4e-05, Method: Composition-based stats. Identities = 12/96 (12%), Positives = 36/96 (37%), Gaps = 7/96 (7%) Query: 151 GKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLG----NATQVQHLSDLLNMSDV 206 + +G IG G +G + + M V+ ++ + A + L + V Sbjct: 2 NRVVGFIGLGRMGQAICRRLLASQMPVHVHNRSREKADDLIRQGAVWAPDIVALTRAARV 61 Query: 207 VSLHVPENPST---KNMMGAKEISLMKPGSLLINAS 239 + + + + + ++ ++ G ++++ S Sbjct: 62 LFVCTAGSEAVQDFYHAPDRGLLACLEVGDIVVDLS 97 >2VHY-A nrPDB Length = 377 Score = 42.6 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 38/97 (39%), Gaps = 14/97 (14%) Query: 156 IIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQV-----------QHLSDLLNMS 204 +IG G G +A +G V DI + L + + Sbjct: 173 VIGAGTAGYNAARIANGMGATVTVLDINIDKLRQLDAEFCGRIHTRYSSAYELEGAVKRA 232 Query: 205 DVVS--LHVPENPSTKNMMGAKEISLMKPGSLLINAS 239 D+V + VP + K ++ ++ MKPG++L++ + Sbjct: 233 DLVIGAVLVPGAKAPK-LVSNSLVAHMKPGAVLVDIA 268 >5H82-A nrPDB Length = 389 Score = 41.9 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 19/54 (35%), Gaps = 2/54 (3%) Query: 146 SFEARGKKLGIIGYGHIGTQLGILAESLGMY--VYFYDIENKLPLGNATQVQHL 197 + G +G++G+G IG A++ G V I K V Sbjct: 208 GLDKPGLSIGVVGFGRIGKLAVKFAKAFGANVTVISTSISKKQEAIEKYGVDRF 261 >4YPO-A nrPDB Length = 333 Score = 40.7 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 33/88 (37%), Gaps = 5/88 (5%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYF----YDIENKLPLGNATQVQHLSDLLNMS 204 +G+K+G+IGYG G + G+ V V +++ + Sbjct: 12 IQGRKVGVIGYGSQGHAHSLSLRDSGVQVRVGLKQGSRSRPKVEEQGLDVDTPAEVAKWA 71 Query: 205 DVVSLHVPENPSTKNMMGAKEISLMKPG 232 DVV + P+ + + +KPG Sbjct: 72 DVVMVLAPDTAQAE-IFAGDIEPNLKPG 98 >2RIR-A nrPDB Length = 300 Score = 40.3 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 14/101 (13%), Positives = 34/101 (33%), Gaps = 11/101 (10%) Query: 145 GSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLG------NATQVQHLS 198 + G ++ ++G G G + +LG V + L Sbjct: 151 TDYTIHGSQVAVLGLGRTGMTIARTFAALGANVKVGARSSAHLARITEMGLVPFHTDELK 210 Query: 199 DLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINAS 239 + + D+ +P ++ +S M P +L+++ + Sbjct: 211 EHVKDIDICINTIPSM-----ILNQTVLSSMTPKTLILDLA 246 >6C55-A nrPDB Length = 340 Score = 40.3 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 28/67 (41%), Gaps = 3/67 (4%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKL---PLGNATQVQHLSDLLNMSD 205 +GKK+ ++GYG G + G V + + V +++ + +D Sbjct: 15 LQGKKIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPVAEAVKQAD 74 Query: 206 VVSLHVP 212 V+ + +P Sbjct: 75 VIMVLLP 81 >4KQW-A nrPDB Length = 350 Score = 39.6 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 27/68 (39%), Gaps = 4/68 (5%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIEN----KLPLGNATQVQHLSDLLNMS 204 +G K+GIIGYG G + G+ V E K +V + + Sbjct: 25 IQGLKVGIIGYGSQGHAHALNLMDSGVDVRVGLREGSSSWKTAEEAGLKVTDMDTAAEEA 84 Query: 205 DVVSLHVP 212 DV+ + VP Sbjct: 85 DVIMVLVP 92 >2GF2-A nrPDB Length = 296 Score = 39.6 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 20/98 (20%), Positives = 38/98 (38%), Gaps = 18/98 (18%) Query: 154 LGIIGYGHIGTQLGILAESLGMYVYFYDIEN----KLPLGNATQVQHLSDLLNMSDVVSL 209 +G IG G++G + G + YD+ + V +D+ +D + Sbjct: 3 VGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFQDAGEQVVSSPADVAEKADRIIT 62 Query: 210 HVPENPSTKNMMGA--------KEISLMKPGSLLINAS 239 +P + + A + +K GSLLI++S Sbjct: 63 MLPTS------INAIEAYSGANGILKKVKKGSLLIDSS 94 >1X14-A nrPDB Length = 401 Score = 39.2 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 43/291 (14%), Positives = 89/291 (30%), Gaps = 59/291 (20%) Query: 2 AKVSLEKDKIKFLLVEGVHQKALESLRAAGYTNIE-----FHKGALDDEQLKESIRDAHF 56 ++ + ++++ K +E L G+T D ++ Sbjct: 8 GRIGIPRERLTNETRVAATPKTVEQLLKLGFTVAVESGAGQLASFDDKAFVQAGAEIVEG 67 Query: 57 -------IGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNT 109 I L+ L +++ + N + A+R + V Sbjct: 68 NSVWQSEIILKVNAPLDDEIALLNPGTTLVSFIWPAQNPELMQKLAERNVTVMAMDSVPR 127 Query: 110 RSVAEL--VIGEL--LLLLRGVPEANAKAHRGVWNKLAAGSFEARGK----KLGIIGYGH 161 S A+ + + + R + EA + + G A GK K+ +IG G Sbjct: 128 ISRAQSLDALSSMANIAGYRAIVEA-----AHEFGRFFTGQITAAGKVPPAKVMVIGAGV 182 Query: 162 IGTQLGILAESLGMYVYFYDIENKLPLGN---ATQVQHLS-------------------- 198 G A SLG V +D ++ + L Sbjct: 183 AGLAAIGAANSLGAIVRAFDTRPEVKEQVQSMGAEFLELDFKEEAGSGDGYAKVMSDAFI 242 Query: 199 ----DLLN----MSDVVSL--HVPENPSTKNMMGAKEISLMKPGSLLINAS 239 +L D++ +P P+ K ++ + + MK GS++++ + Sbjct: 243 KAEMELFAAQAKEVDIIVTTALIPGKPAPK-LITREMVDSMKAGSVIVDLA 292 >2EEZ-A nrPDB Length = 369 Score = 38.4 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 46/112 (41%), Gaps = 18/112 (16%) Query: 156 IIGYGHIGTQLGILAESLGMYVYFYDIENKLPL-----------GNATQVQHLSDLLNMS 204 I+G G +GT +A +G V D+ +K ++ + + Sbjct: 171 ILGGGTVGTNAAKIALGMGAQVTILDVNHKRLQYLDDVFGGRVITLTATEANIKKSVQHA 230 Query: 205 DVVS--LHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALA 254 D++ + VP + K ++ +SLMK G+++++ + VD + + Sbjct: 231 DLLIGAVLVPGAKAPK-LVTRDMLSLMKEGAVIVDVA----VDQGGCVETIR 277 >1V9L-A nrPDB Length = 421 Score = 38.4 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 26/87 (29%), Gaps = 21/87 (24%) Query: 103 NAPFSNT--------RSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKL 154 N P T V E G GV A + + +W GK + Sbjct: 167 NVPGVFTSKPPELWGNPVREYATGF------GVAVATREMAKKLWGG-------IEGKTV 213 Query: 155 GIIGYGHIGTQLGILAESLGMYVYFYD 181 I G G++G E +G V Sbjct: 214 AIQGMGNVGRWTAYWLEKMGAKVIAVS 240 >1VPD-A nrPDB Length = 299 Score = 38.4 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 28/125 (22%), Positives = 46/125 (36%), Gaps = 6/125 (4%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGN----ATQVQHLSDLLNMSDVV 207 K+G IG G +G + G + D + A + DV+ Sbjct: 6 MKVGFIGLGIMGKPMSKNLLKAGYSLVVSDRNPEAIADVIAAGAETASTAKAIAEQCDVI 65 Query: 208 SLHVPENPSTKNMMGAK--EISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDV 265 +P +P K + + I KPG++LI+ S + + DAL +K + V Sbjct: 66 ITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISDALKAKGVEMLDAPV 125 Query: 266 FPTEP 270 EP Sbjct: 126 SGGEP 130 >1GTM-A nrPDB Length = 419 Score = 37.2 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 12/35 (34%), Positives = 16/35 (45%), Gaps = 1/35 (2%) Query: 148 EARGKKLGIIGYGHIGTQLGILA-ESLGMYVYFYD 181 +GK + I GYG+ G L + E GM V Sbjct: 209 TLKGKTIAIQGYGNAGYYLAKIMSEDFGMKVVAVS 243 >4TSK-A nrPDB Length = 350 Score = 36.9 bits (84), Expect = 0.017, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 24/67 (35%), Gaps = 3/67 (4%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLP---LGNATQVQHLSDLLNMSD 205 K++ +IGYG G G V + +V + + + SD Sbjct: 15 LADKRIAVIGYGSQGHAHAQNLRDSGFDVVIGLRPGSSWAKAEADGFRVMAVGEAVEESD 74 Query: 206 VVSLHVP 212 V+ + +P Sbjct: 75 VIMILLP 81 >1NP3-A nrPDB Length = 338 Score = 36.9 bits (84), Expect = 0.018, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 36/92 (39%), Gaps = 7/92 (7%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKL----PLGNATQVQHLSDLLNMS 204 +GKK+ IIGYG G + G+ V + +V + + + Sbjct: 14 IQGKKVAIIGYGSQGHAHACNLKDSGVDVTVGLRSGSATVAKAEAHGLKVADVKTAVAAA 73 Query: 205 DVVSLHVPENPSTKNMMGAKEIS-LMKPGSLL 235 DVV + P + + +EI +K G+ L Sbjct: 74 DVVMILTP--DEFQGRLYKEEIEPNLKKGATL 103 >1GPJ-A nrPDB Length = 404 Score = 36.5 bits (83), Expect = 0.020, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 25/72 (34%), Gaps = 8/72 (11%) Query: 148 EARGKKLGIIGYGHIGTQLGILAESLGMY-VYFYDIENKLPL-------GNATQVQHLSD 199 K + ++G G +G + G+ V + + + G A + L D Sbjct: 164 SLHDKTVLVVGAGEMGKTVAKSLVDRGVRAVLVANRTYERAVELARDLGGEAVRFDELVD 223 Query: 200 LLNMSDVVSLHV 211 L SDVV Sbjct: 224 HLARSDVVVSAT 235 >3PVJ-A nrPDB Length = 277 Score = 36.5 bits (83), Expect = 0.021, Method: Composition-based stats. Identities = 20/115 (17%), Positives = 41/115 (35%), Gaps = 2/115 (1%) Query: 246 IPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIG 305 PAL L++K L D + ++PL E + L H T+ Sbjct: 105 TPALGAVLSAKQLPAYGGDTLWASGIAAFEALSAPLREMLDGLTATHD--FTKSFPLERF 162 Query: 306 LEVAGKLIKYSDNGSTLSAVNFPEVSLPLHGGRRLMHIHENRPGVLTALNKIFAE 360 L ++ ++ P V GR+ + ++E + L+++ ++ Sbjct: 163 GTTPQDLARWEATRRNNPPLSHPVVRTHPVSGRKALFVNEGFTTRINELSELESD 217 >6ACF-A nrPDB Length = 367 Score = 36.5 bits (83), Expect = 0.022, Method: Composition-based stats. Identities = 16/99 (16%), Positives = 32/99 (32%), Gaps = 10/99 (10%) Query: 141 KLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIEN----KLPLGNATQVQH 196 K A GS GK + + G G++ L G + DI + + Sbjct: 163 KEAFGSDSLEGKVVAVQGVGNVAYHLCRHLHEEGAKLIVTDINKEAVARAVEEFGAKAVD 222 Query: 197 LSDLLN-MSDVVSLHVPENPSTKNMMGAKEISLMKPGSL 234 +D+ D+ + ++ + I +K + Sbjct: 223 PNDIYGVECDIFAP-CAL----GGIINDQTIPQLKAKVI 256 >3AOE-E nrPDB Length = 419 Score = 36.5 bits (83), Expect = 0.022, Method: Composition-based stats. Identities = 11/39 (28%), Positives = 18/39 (46%) Query: 145 GSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIE 183 + RG ++ + G G +G + + AE LGM V Sbjct: 212 RGLDLRGARVVVQGLGQVGAAVALHAERLGMRVVAVATS 250 >4XDZ-A nrPDB Length = 343 Score = 36.5 bits (83), Expect = 0.023, Method: Composition-based stats. Identities = 16/92 (17%), Positives = 37/92 (40%), Gaps = 5/92 (5%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYF----YDIENKLPLGNATQVQHLSDLLNMS 204 + K + I+GYG G + G+ V + + + + + D + ++ Sbjct: 15 IKNKTIAILGYGSQGRAWALNLRDSGLNVVVGLERQGDSWRRAIDDGFKPMYTKDAVAIA 74 Query: 205 DVVSLHVPENPSTKNMMGAKEISLMKPGSLLI 236 D++ VP+ + + + MK G+ L+ Sbjct: 75 DIIVFLVPDMVQKSLWLNSVK-DFMKKGADLV 105 >5E4R-A nrPDB Length = 490 Score = 36.5 bits (83), Expect = 0.024, Method: Composition-based stats. Identities = 16/92 (17%), Positives = 37/92 (40%), Gaps = 5/92 (5%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYF----YDIENKLPLGNATQVQHLSDLLNMS 204 + K + I+GYG G + G+ V + + + + + D + ++ Sbjct: 15 IKNKTIAILGYGSQGRAWALNLRDSGLNVVVGLERQGDSWRRAIDDGFKPMYTKDAVAIA 74 Query: 205 DVVSLHVPENPSTKNMMGAKEISLMKPGSLLI 236 D++ VP+ + + + MK G+ L+ Sbjct: 75 DIIVFLVPDMVQKSLWLNSVK-DFMKKGADLV 105 >4WJI-A nrPDB Length = 293 Score = 36.5 bits (83), Expect = 0.025, Method: Composition-based stats. Identities = 19/103 (18%), Positives = 44/103 (42%), Gaps = 12/103 (11%) Query: 152 KKLGIIGYGHIGTQLGI--LAESLGMYVYFYDIE-----NKLPLGNATQVQ-HLSDLLNM 203 + + +IG G IG+ + + L + LG + ++ + Sbjct: 5 QTIALIGIGLIGSSIARDIREKQLAGTIVVTTRSEATLKRAGELGLGDRYTLSAAEAVEG 64 Query: 204 SDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINAS--RGTVV 244 +D+V + VP S + A+ + +KPG+++ + +G+V+ Sbjct: 65 ADLVVVSVPVGAS--GAVAAEIAAHLKPGAIVTDVGSTKGSVI 105 >2RCY-A nrPDB Length = 262 Score = 36.1 bits (82), Expect = 0.026, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 26/67 (38%), Gaps = 6/67 (8%) Query: 149 ARGKKLGIIGYGHIGTQLGI-LAESLGMY---VYFYDIENKLPLGNATQVQHLSDLLNMS 204 KLG +G G +G+ L +A + + +++Y K + +L Sbjct: 2 MENIKLGFMGLGQMGSALAHGIANANIIKKENLFYYGPSKK--NTTLNYMSSNEELARHC 59 Query: 205 DVVSLHV 211 D++ V Sbjct: 60 DIIVCAV 66 >1NPD-A nrPDB Length = 288 Score = 36.1 bits (82), Expect = 0.026, Method: Composition-based stats. Identities = 28/183 (15%), Positives = 52/183 (28%), Gaps = 38/183 (20%) Query: 126 GVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMY-VYFYDIEN 184 G G + F+ +GK + ++G G T +G G+ + ++ + Sbjct: 99 GYLRGYNTDGTGHIRAIKESGFDIKGKTMVLLGAGGASTAIGAQGAIEGLKEIKLFNRRD 158 Query: 185 KLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVV 244 + Q +++ +D V + Sbjct: 159 EFFDKALAFAQRVNE---NTDCVVTVT------------------------------DLA 185 Query: 245 DIPALCDALASKHLAGAAIDV----FPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEA 300 D A +ALAS + V E N P + PH+ Q+A Sbjct: 186 DQQAFAEALASADILTNGTKVGMKPLENESLVNDISLLHPGLLVTECVYNPHMTKLLQQA 245 Query: 301 QEN 303 Q+ Sbjct: 246 QQA 248 >3ABT-A nrPDB Length = 662 Score = 36.1 bits (82), Expect = 0.030, Method: Composition-based stats. Identities = 13/51 (25%), Positives = 22/51 (43%), Gaps = 1/51 (1%) Query: 127 VPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYV 177 E + + G++ ++ + GK + IIG G G +S GM V Sbjct: 84 YLERHGLINFGIYKRIKPLPTKKTGKVI-IIGSGVSGLAAARQLQSFGMDV 133 >2PV7-A nrPDB Length = 298 Score = 36.1 bits (82), Expect = 0.030, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 26/74 (35%), Gaps = 15/74 (20%) Query: 158 GYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPST 217 GYG +G + G + D E +L +DVV + VP N Sbjct: 29 GYGKLGGLFARYLRASGYPISILDRE---------DWAVAESILANADVVIVSVPIN--- 76 Query: 218 KNMMGAKEISLMKP 231 + + I +KP Sbjct: 77 ---LTLETIERLKP 87 >1BVU-A nrPDB Length = 418 Score = 36.1 bits (82), Expect = 0.032, Method: Composition-based stats. Identities = 12/43 (27%), Positives = 18/43 (41%), Gaps = 1/43 (2%) Query: 140 NKLAAGSFEARGKKLGIIGYGHIGTQLGILA-ESLGMYVYFYD 181 A + +GK + I GYG+ G + + E GM V Sbjct: 200 EAAKALGMDLKGKTIAIQGYGNAGYYMAKIMSEEYGMKVVAVS 242 >1H2H-A nrPDB Length = 241 Score = 35.7 bits (81), Expect = 0.036, Method: Composition-based stats. Identities = 18/58 (31%), Positives = 26/58 (44%), Gaps = 6/58 (10%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSL 209 + IIG G+IG +L L +Y YD +K G V L + SDV ++ Sbjct: 1 MTVLIIGMGNIGKKLVELGNF--EKIYAYDRISKDIPG----VVRLDEFQVPSDVSTV 52 >5YEQ-A nrPDB Length = 340 Score = 35.7 bits (81), Expect = 0.037, Method: Composition-based stats. Identities = 11/68 (16%), Positives = 25/68 (36%), Gaps = 4/68 (5%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYF----YDIENKLPLGNATQVQHLSDLLNMS 204 + K++ ++GYG G + G+ V K + + + + S Sbjct: 15 IKEKRVAVLGYGSQGRAWALNLRDSGIKVSVGLEREGNSWKQAENDGFKPLRTEEAVRNS 74 Query: 205 DVVSLHVP 212 D++ +P Sbjct: 75 DIIIFLLP 82 >5L3D-A nrPDB Length = 852 Score = 35.7 bits (81), Expect = 0.040, Method: Composition-based stats. Identities = 13/51 (25%), Positives = 22/51 (43%), Gaps = 1/51 (1%) Query: 127 VPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYV 177 E + + G++ ++ + GK + IIG G G +S GM V Sbjct: 255 YLERHGLINFGIYKRIKPLPTKKTGKVI-IIGSGVSGLAAARQLQSFGMDV 304 >3VPX-A nrPDB Length = 364 Score = 35.7 bits (81), Expect = 0.041, Method: Composition-based stats. Identities = 14/99 (14%), Positives = 33/99 (33%), Gaps = 10/99 (10%) Query: 141 KLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIE----NKLPLGNATQVQH 196 K A G GK + + G G++ L G + DI + Sbjct: 163 KEAFGDDSLAGKTVAVQGVGNVAYALCEYLHEEGAKLIITDINEEAVQRAVDAFGATAVG 222 Query: 197 LSDLLNM-SDVVSLHVPENPSTKNMMGAKEISLMKPGSL 234 ++++ + +D+ + ++ + I +K + Sbjct: 223 INEIYSQEADIFAP-CALGA----IINDETIPQLKAKVI 256 >3TWO-A nrPDB Length = 348 Score = 35.3 bits (80), Expect = 0.043, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 28/70 (40%), Gaps = 5/70 (7%) Query: 150 RGKKLGIIGYGHIGTQLGILAESLGMYVYFYDI-----ENKLPLGNATQVQHLSDLLNMS 204 +G K+G+ G+G +G+ A ++G V + ++ L +G Sbjct: 176 KGTKVGVAGFGGLGSMAVKYAVAMGAEVSVFARNEHKKQDALSMGVKHFYTDPKQCKEEL 235 Query: 205 DVVSLHVPEN 214 D + +P + Sbjct: 236 DFIISTIPTH 245 >2CZC-A nrPDB Length = 334 Score = 35.3 bits (80), Expect = 0.045, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 29/85 (34%), Gaps = 25/85 (29%) Query: 153 KLGIIGYGHIGTQL-----------------------GILAESLGMYVYFYDIE--NKLP 187 K+G+ GYG IG ++ A+ LG+ VY E + Sbjct: 4 KVGVNGYGTIGKRVAYAVTKQDDMELIGITKTKPDFEAYRAKELGIPVYAASEEFIPRFE 63 Query: 188 LGNATQVQHLSDLLNMSDVVSLHVP 212 L+DLL D++ P Sbjct: 64 KEGFEVAGTLNDLLEKVDIIVDATP 88 >4PZE-A nrPDB Length = 284 Score = 35.3 bits (80), Expect = 0.045, Method: Composition-based stats. Identities = 14/53 (26%), Positives = 24/53 (45%), Gaps = 1/53 (1%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIEN-KLPLGNATQVQHLSDLLNM 203 + +GI+G G +G + +G+ V DI + + G AT L L+ Sbjct: 4 RTVGIVGAGTMGNGIAQACAVVGLNVVMVDISDAAVQKGVATVASSLDRLIKK 56 >6F3O-A nrPDB Length = 472 Score = 34.9 bits (79), Expect = 0.065, Method: Composition-based stats. Identities = 19/108 (17%), Positives = 37/108 (34%), Gaps = 21/108 (19%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIEN-----------------KLPLGNA 191 GK+ +IGYG +G GM V +++ K + + Sbjct: 222 LSGKQALVIGYGDVGKGSSQSLRQEGMIVKVAEVDPICAMQACMDGFEVVSPYKNGINDG 281 Query: 192 TQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINAS 239 T+ + LL D++ N+ A + +K +++ N Sbjct: 282 TEASIDAALLGKIDLIVT----TTGNVNVCDANMLKALKKRAVVCNIG 325 >4D3F-A nrPDB Length = 310 Score = 34.9 bits (79), Expect = 0.065, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 28/64 (43%), Gaps = 4/64 (6%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLP----LGNATQVQHLSDLLNMSDVV 207 K + +IG G +G + + G V ++ + A +V +++ L +++V Sbjct: 22 KSVTVIGLGPMGQAMADVFLEYGYSVTVWNRTSSKADQLVAKGAIRVSTVNEALAANELV 81 Query: 208 SLHV 211 L + Sbjct: 82 ILSL 85 >4XDY-A nrPDB Length = 338 Score = 34.9 bits (79), Expect = 0.072, Method: Composition-based stats. Identities = 17/98 (17%), Positives = 33/98 (33%), Gaps = 12/98 (12%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYF---------YDIENKLPLGNATQVQHLSD 199 R K + ++GYG G + G+ V + + + +V + Sbjct: 14 LRDKTIAVMGYGAQGDAQANCLKDSGINVVIGETEILGGNKNPSWEKAKEDGFEVLPIDK 73 Query: 200 LLNMSDVVSLHVPENPSTKNMMGAKEIS-LMKPGSLLI 236 DVV + +P + + +I +K G L Sbjct: 74 AAEKGDVVHILLP--DEVQPAIYENQIKPQLKAGKALC 109 >3DZB-A nrPDB Length = 317 Score = 34.5 bits (78), Expect = 0.083, Method: Composition-based stats. Identities = 18/101 (17%), Positives = 30/101 (29%), Gaps = 11/101 (10%) Query: 148 EARGKKLGIIGYGHIGTQLG---ILAESLGMYVYFY---DIENKLPLGNA---TQVQHLS 198 K + I G G IG L + Y D + L Sbjct: 2 SLSKKTIYIAGLGLIGGSLALGIKRDHP-DYEILGYNRSDYSRNIALERGIVDRATGDFK 60 Query: 199 DLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINAS 239 + ++DV+ L VP T + +K ++ +A Sbjct: 61 EFAPLADVIILAVPI-KQTMAYLKELADLDLKDNVIITDAG 100 >1A5Z-A nrPDB Length = 319 Score = 34.5 bits (78), Expect = 0.085, Method: Composition-based stats. Identities = 22/101 (21%), Positives = 40/101 (39%), Gaps = 23/101 (22%) Query: 152 KKLGIIGYGHIGT--QLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDL--------- 200 K+GI+G G +G+ +L + + D++ K G+A + H + Sbjct: 1 MKIGIVGLGRVGSSTAFALLMKGFAREMVLIDVDKKRAEGDALDLIHGTPFTRRANIYAG 60 Query: 201 ----LNMSDVVSLH--VPENPSTKNMMGAKEISLMKPGSLL 235 L SDVV + VP+ P G + L+ + + Sbjct: 61 DYADLKGSDVVIVAAGVPQKP------GETRLQLLGRNARV 95 >3ULK-A nrPDB Length = 491 Score = 34.5 bits (78), Expect = 0.092, Method: Composition-based stats. Identities = 25/121 (20%), Positives = 45/121 (37%), Gaps = 11/121 (9%) Query: 124 LRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIE 183 LR K ++ A G+ +GKK+ I+G G G G+ G+ + + + Sbjct: 10 LRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRK 69 Query: 184 NKLPL---------GNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSL 234 + N +V +L+ +D+V P + + LMK G+ Sbjct: 70 EAIAEKRASWRKATENGFKVGTYEELIPQADLVINLTP--DKQHSDVVRTVQPLMKDGAA 127 Query: 235 L 235 L Sbjct: 128 L 128 >4R16-A nrPDB Length = 418 Score = 34.2 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 25/48 (52%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSD 199 ++ ++G G+IG I+ S G V YDI +++ + V H+ + Sbjct: 1 MRIAVLGLGYIGLPTAIMFASSGYDVVGYDIRSEVIKKINSGVAHIIE 48 >1CRW-G nrPDB Length = 333 Score = 34.2 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 15/84 (17%), Positives = 30/84 (35%), Gaps = 20/84 (23%) Query: 153 KLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVP 212 K+GI G+G IG + A +G V + ++++ + Sbjct: 2 KIGINGFGRIGRLVLRAALEMGAQVVAVN-------DPFIALEYMVYMFK---------- 44 Query: 213 ENPSTKNMMGAKEISLMKPGSLLI 236 ST M + + G+L++ Sbjct: 45 -YDSTHGMFKGEV--KAEDGALVV 65 >3G0O-A nrPDB Length = 303 Score = 34.2 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 43/116 (37%), Gaps = 7/116 (6%) Query: 145 GSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENK-----LPLGNATQVQHLSD 199 S +GI+G G +G G+ + D+ + L G + Sbjct: 1 MSLTGTDFHVGIVGLGSMGMGAARSCLRAGLSTWGADLNPQACANLLAEGACGAAASARE 60 Query: 200 LLNMSDVVSLHVPENPSTKN-MMGAKEIS-LMKPGSLLINASRGTVVDIPALCDAL 253 + D + + V + + G ++ LMKPGS ++ +S + D + AL Sbjct: 61 FAGVVDALVILVVNAAQVRQVLFGEDGVAHLMKPGSAVMVSSTISSADAQEIAAAL 116 >2F1K-A nrPDB Length = 279 Score = 34.2 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 36/96 (37%), Gaps = 13/96 (13%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSD------LLNMSD 205 K+G++G G IG L G Y+ + A + Q + + LL + Sbjct: 1 MKIGVVGLGLIGASLAGDLRRRGHYLIGVSRQQSTCE-KAVERQLVDEAGQDLSLLQTAK 59 Query: 206 VVSLHVP--ENPSTKNMMGAKEISLMKPGSLLINAS 239 ++ L P T K I + P +++ + + Sbjct: 60 IIFLCTPIQLILPTL----EKLIPHLSPTAIVTDVA 91 >6JDK-A nrPDB Length = 544 Score = 34.2 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 27/70 (38%), Gaps = 3/70 (4%) Query: 130 ANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLG 189 A H G+W + A GK++G++G G G Q+ A ++ + L L Sbjct: 168 AGESFHTGLWPQEGA---SFTGKRVGVVGTGASGVQVVQEASKDAAHLTVFQRTPILALP 224 Query: 190 NATQVQHLSD 199 + + Sbjct: 225 MQQRKLDVET 234 >4OM8-A nrPDB Length = 309 Score = 34.2 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 24/61 (39%), Gaps = 3/61 (4%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHV 211 + + IIG G +G + G+ V YD+ + + +L D + + + Sbjct: 3 RNIAIIGLGTMGPGMAARLARGGLQVVAYDVAPAAIERARSMLSVAETVL---DALGIAL 59 Query: 212 P 212 P Sbjct: 60 P 60 >3MOG-A nrPDB Length = 483 Score = 33.8 bits (76), Expect = 0.14, Method: Composition-based stats. Identities = 11/39 (28%), Positives = 18/39 (46%) Query: 148 EARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKL 186 + + +IG G +G + +A S G V YDI + Sbjct: 2 SLNVQTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEA 40 >3F3S-A nrPDB Length = 313 Score = 33.8 bits (76), Expect = 0.14, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 23/57 (40%), Gaps = 1/57 (1%) Query: 148 EARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMS 204 G + I+G G IG +L S G V YDIE + ++ LL + Sbjct: 1 SMAGCVV-IVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQA 56 >2CZG-A nrPDB Length = 433 Score = 33.8 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 17/96 (17%), Positives = 38/96 (39%), Gaps = 7/96 (7%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHV 211 +K+ ++G G +G ++ I A+ LG+ V D P ++ ++++ D + V Sbjct: 20 QKILLLGSGELGKEIAIEAQRLGVEVVAVDRYANAPAMQVAHRSYVGNMMDK-DFLWSVV 78 Query: 212 ------PENPSTKNMMGAKEISLMKPGSLLINASRG 241 P + + K G ++ +R Sbjct: 79 EREKPDAIIPEIEAINLDALFEFEKDGYFVVPNARA 114 >5Y8M-A nrPDB Length = 295 Score = 33.8 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 19/108 (17%), Positives = 38/108 (35%), Gaps = 5/108 (4%) Query: 153 KLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQ----VQHLSDLLNMSDVVS 208 + +G G++G + G V +D G A + + + +DVV Sbjct: 4 TIAFLGLGNMGAPMSANLVGAGHVVRGFDPAPTAASGAAAHGVAVFRSAPEAVAEADVVI 63 Query: 209 LHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASK 256 +P ++ +P +L I++S +V D + S Sbjct: 64 TMLP-TGEVVRRCYTDVLAAARPATLFIDSSTISVTDAREVHALAESH 110 >5G6R-A nrPDB Length = 295 Score = 33.8 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 26/64 (40%), Gaps = 4/64 (6%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQ----VQHLSDLLNMSDVV 207 K +GI G G +GT L G ++ + Q +S+ +N +D++ Sbjct: 3 KHIGIFGLGAMGTALAAKYLEHGYKTSVWNRTTAKAIPLVEQGAKLASTISEGVNANDLI 62 Query: 208 SLHV 211 + + Sbjct: 63 IICL 66 >6AON-A nrPDB Length = 478 Score = 33.8 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 26/107 (24%), Positives = 42/107 (39%), Gaps = 17/107 (15%) Query: 99 IPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIG 158 I V + VA+ VI R +P + + + A + A KKLG+IG Sbjct: 137 IKVTGTTDA--DLVAKHVIVATGSSARELP-GLPFDEKNILSNDGALNIGAVPKKLGVIG 193 Query: 159 YGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSD 205 G IG ++G + LG V T ++ + + L +D Sbjct: 194 AGVIGLEMGSVWRRLGAEV--------------TILEAMPEFLAAAD 226 >3B1F-A nrPDB Length = 290 Score = 33.4 bits (75), Expect = 0.18, Method: Composition-based stats. Identities = 19/100 (19%), Positives = 33/100 (33%), Gaps = 11/100 (11%) Query: 149 ARGKKLGIIGYGHIGTQLG---ILAESLGMYVYFY---DIENKLPLGNATQVQHLSD--- 199 K + I G G IG L + Y D + L + +D Sbjct: 4 MEEKTIYIAGLGLIGASLALGIKRDHPH-YKIVGYNRSDRSRDIALERGIVDEATADFKV 62 Query: 200 LLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINAS 239 ++DV+ L VP T + + +K ++ +A Sbjct: 63 FAALADVIILAVPI-KKTIDFIKILADLDLKEDVIITDAG 101 >3AOE-A nrPDB Length = 424 Score = 33.4 bits (75), Expect = 0.19, Method: Composition-based stats. Identities = 11/77 (14%), Positives = 23/77 (29%), Gaps = 16/77 (20%) Query: 146 SFEARGKKLGIIGYGHIGTQLGILAESLGMYVYF----------------YDIENKLPLG 189 + G ++ I G+G++G G V YD+ + Sbjct: 214 GLQVEGARVAIQGFGNVGNAAARAFHDHGARVVAVQDHTGTVYNEAGIDPYDLLRHVQEF 273 Query: 190 NATQVQHLSDLLNMSDV 206 + ++ L +D Sbjct: 274 GGVRGYPKAEPLPAADF 290 >1YB4-A nrPDB Length = 295 Score = 33.4 bits (75), Expect = 0.20, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 30/68 (44%), Gaps = 3/68 (4%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIEN---KLPLGNATQVQHLSDLLNMSDVVS 208 KLG IG G +G+ + I G ++ I +L A V+ + +D++ Sbjct: 4 MKLGFIGLGIMGSPMAINLARAGHQLHVTTIGPVADELLSLGAVNVETARQVTEFADIIF 63 Query: 209 LHVPENPS 216 + VP+ P Sbjct: 64 IMVPDTPQ 71 >3CKY-A nrPDB Length = 301 Score = 33.4 bits (75), Expect = 0.20, Method: Composition-based stats. Identities = 20/93 (21%), Positives = 39/93 (41%), Gaps = 6/93 (6%) Query: 153 KLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSD----LLNMSDVVS 208 K+G IG G +G + I G+ VY +D+ Q + + SD++ Sbjct: 6 KIGFIGLGAMGKPMAINLLKEGVTVYAFDLMEANVAAVVAQGAQACENNQKVAAASDIIF 65 Query: 209 LHVPENPSTKNMMGAK--EISLMKPGSLLINAS 239 +P + +M +S K G+++++ S Sbjct: 66 TSLPNAGIVETVMNGPGGVLSACKAGTVIVDMS 98 >5XVH-A nrPDB Length = 306 Score = 33.4 bits (75), Expect = 0.21, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 27/74 (36%), Gaps = 4/74 (5%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKL----PLGNATQVQHLSDLLNMSDVV 207 ++G IG G +G + G Y+ + + +DL DVV Sbjct: 21 MRVGFIGLGIMGGPMATHLLKAGFLAAVYNRTREKTKPFAEAGVYVAESPADLAKRVDVV 80 Query: 208 SLHVPENPSTKNMM 221 + V + P + ++ Sbjct: 81 IVMVSDAPDVEQVL 94 >2R9Z-A nrPDB Length = 463 Score = 33.4 bits (75), Expect = 0.21, Method: Composition-based stats. Identities = 14/35 (40%), Positives = 21/35 (60%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKL 186 K++ IIG G+IG +L L S G V +E++L Sbjct: 167 KRVAIIGAGYIGIELAGLLRSFGSEVTVVALEDRL 201 >2HK7-A nrPDB Length = 269 Score = 33.0 bits (74), Expect = 0.21, Method: Composition-based stats. Identities = 10/88 (11%), Positives = 27/88 (30%), Gaps = 7/88 (7%) Query: 148 EARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQ-----HLSDLLN 202 E + K + ++G G + G V+ ++ + + A + ++++ Sbjct: 120 EVKEKSILVLGAGGASRAVIYALVKEGAKVFLWNRTKEKAIKLAQKFPLEVVNSPEEVID 179 Query: 203 MSDVVSL--HVPENPSTKNMMGAKEISL 228 V+ V + I Sbjct: 180 KVQVIVNTTSVGLKDEDPEIFNYDLIKK 207 >2HMT-A nrPDB Length = 144 Score = 33.0 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 18/48 (37%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQH 196 + K+ +IG G G + +G V DI + A+ H Sbjct: 4 IKNKQFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASYATH 51 >6IQV-A nrPDB Length = 340 Score = 33.0 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 33/85 (38%), Gaps = 16/85 (18%) Query: 153 KLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVP 212 K+GI G+G IG LG + +V ++DL S + H+ Sbjct: 4 KIGINGFGRIGRLAFRRILELG------------EKSSDIEVVAINDL--TSPALLAHLL 49 Query: 213 ENPSTKNMMGAKEISLMKPGSLLIN 237 + ST + A + S+++N Sbjct: 50 KYDSTHGTLNADVSAT--DDSIVVN 72 >5BUT-A nrPDB Length = 288 Score = 33.0 bits (74), Expect = 0.23, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 18/48 (37%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQH 196 + K+ +IG G G + +G V DI + A+ H Sbjct: 4 IKNKQFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASYATH 51 Score = 31.5 bits (70), Expect = 0.75, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 17/45 (37%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQH 196 K+ +IG G G + +G V DI + A+ H Sbjct: 149 KQFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASYATH 193 >1EZ1-A nrPDB Length = 392 Score = 33.0 bits (74), Expect = 0.23, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 40/94 (42%), Gaps = 5/94 (5%) Query: 153 KLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLL---NMSDVVSL 209 ++ ++G G +G ++ I + LG+ V D P + H+ ++L + VV L Sbjct: 14 RVMLLGSGELGKEVAIECQRLGVEVIAVDRYADAPAMHVAHRSHVINMLDGDALRRVVEL 73 Query: 210 HVP--ENPSTKNMMGAKEISLMKPGSLLINASRG 241 P P + + I L + G ++ +R Sbjct: 74 EKPHYIVPEIEAIATDMLIQLEEEGLNVVPCARA 107 >1CER-O nrPDB Length = 331 Score = 33.0 bits (74), Expect = 0.23, Method: Composition-based stats. Identities = 13/47 (27%), Positives = 23/47 (48%), Gaps = 1/47 (2%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYV-YFYDIENKLPLGNATQVQHL 197 K+GI G+G IG Q+ + S G+ V D+ + L + + + Sbjct: 1 MKVGINGFGRIGRQVFRILHSRGVEVALINDLTDNKTLAHLLKYDSI 47 >4G65-A nrPDB Length = 461 Score = 33.0 bits (74), Expect = 0.24, Method: Composition-based stats. Identities = 20/106 (18%), Positives = 41/106 (38%), Gaps = 13/106 (12%) Query: 152 KKLGIIGYGHIGTQLGILAE-SLGMYVYFYDIENKLPLGNATQV-------QHLSDLLNM 203 +++ I+G G+IG L E + + + +++ L + +LL Sbjct: 236 RRIMIVGGGNIGASLAKRLEQTYSVKLIERNLQRAEKLSEELENTIVFCGDAADQELLTE 295 Query: 204 SDV----VSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVD 245 ++ V + + T N+M A M +++ RG VD Sbjct: 296 ENIDQVDVFIALTNEDET-NIMSAMLAKRMGAKKVMVLIQRGAYVD 340 >5U9P-A nrPDB Length = 265 Score = 33.0 bits (74), Expect = 0.25, Method: Composition-based stats. Identities = 19/107 (17%), Positives = 36/107 (33%), Gaps = 9/107 (8%) Query: 142 LAAGSFEARGKKLGIIGYGH-IGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDL 200 A F G++ I G G IG L G + D + A + + + Sbjct: 11 HALDRFRLDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARRFR--DEG 68 Query: 201 LNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINAS----RGTV 243 +D V E+ + + E + + +L+N + R + Sbjct: 69 FA-ADHAVFDVAEHAQVRAAIDEFE-ARVGAIDILVNNAGIQRRAPL 113 >3FBG-A nrPDB Length = 346 Score = 33.0 bits (74), Expect = 0.25, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 20/42 (47%), Gaps = 1/42 (2%) Query: 148 EARGKKLGII-GYGHIGTQLGILAESLGMYVYFYDIENKLPL 188 E GK L II G G +G+ +A++ G+ V N+ Sbjct: 148 ENEGKTLLIINGAGGVGSIATQIAKAYGLRVITTASRNETIE 189 >3ADO-A nrPDB Length = 319 Score = 33.0 bits (74), Expect = 0.25, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 18/36 (50%) Query: 154 LGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLG 189 + I+G G +G +L S G V YDIE + G Sbjct: 9 VLIVGSGLVGRSWAMLFASGGFRVKLYDIEPRQITG 44 >3F9I-A nrPDB Length = 249 Score = 33.0 bits (74), Expect = 0.26, Method: Composition-based stats. Identities = 20/132 (15%), Positives = 37/132 (28%), Gaps = 40/132 (30%) Query: 148 EARGKKLGIIGYGH-IGTQLGILAESLGMYVYFYDIENKLPLGNATQV------------ 194 + GK I G IG+ + L LG V + + Sbjct: 11 DLTGKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYTIEVCNLA 70 Query: 195 --QHLSDLLNMS---DVVSLHVPENPSTKN--------------------MMGAKEISLM 229 + S+L++ + D++ + T ++ + I M Sbjct: 71 NKEECSNLISKTSNLDILVCNAGITSDTLAIRMKDQDFDKVIDINLKANFILNREAIKKM 130 Query: 230 --KPGSLLINAS 239 K +IN S Sbjct: 131 IQKRYGRIINIS 142 >6HD1-C nrPDB Length = 459 Score = 33.0 bits (74), Expect = 0.27, Method: Composition-based stats. Identities = 16/92 (17%), Positives = 37/92 (40%), Gaps = 6/92 (6%) Query: 150 RGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKL--PLGNATQVQHLSDLLNMSDVV 207 + + + I G G G LG+ G V F + L + +V S+ S ++ Sbjct: 18 KQETVCIFGTGDFGRSLGLKMLQCGYSVVFGSRNPQKTTLLPSGAEVLSYSEAAKKSGII 77 Query: 208 SLHVPENPSTKNMMGAKEISLMKPGSLLINAS 239 + + + + + ++ + G +L++ S Sbjct: 78 IIAI--HREHYDFLTE--LTEVLNGKILVDIS 105 >4J90-A nrPDB Length = 222 Score = 33.0 bits (74), Expect = 0.28, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 18/48 (37%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQH 196 + K+ +IG G G + +G V DI + A+ H Sbjct: 4 IKNKQFAVIGLGRFGGSICKELHRMGHEVLAVDINEEKVNAYASYATH 51 >3PII-A nrPDB Length = 339 Score = 32.6 bits (73), Expect = 0.28, Method: Composition-based stats. Identities = 40/204 (19%), Positives = 69/204 (33%), Gaps = 35/204 (17%) Query: 151 GKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNM--SDVVS 208 G+ + I G G G A+++G+ V DI ++ +L +D+V Sbjct: 165 GEWVAIYGIGGFGHVAVQYAKAMGLNVVAVDIGDEKL-----------ELAKELGADLVV 213 Query: 209 LHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPT 268 P MK ++A+ T V PA A S GA + Sbjct: 214 N--PL--------KEDAAKFMKEKVGGVHAAVVTAVSKPAFQSAYNSIRRGGACV----- 258 Query: 269 EPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDNGSTLSAVNFP 328 P P+ FD VL I GS +++ + ++++ G + + Sbjct: 259 --LVGLPPEEMPIPIFDTVLNGIKIIGSIVGTRKD-----LQEALQFAAEGKVKTIIEVQ 311 Query: 329 EVSLPLHGGRRLMHIHENRPGVLT 352 + R++ N VLT Sbjct: 312 PLEKINEVFDRMLKGQINGRVVLT 335 >3UP5-A nrPDB Length = 545 Score = 32.6 bits (73), Expect = 0.30, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 22/57 (38%), Gaps = 3/57 (5%) Query: 132 AKAHRGVWNKLAAG---SFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENK 185 H W A G + GK++G+IG G G Q+ +A +Y + Sbjct: 163 ESFHSSRWPTDAEGAPKGVDFTGKRVGVIGTGATGVQIIPIAAETAKELYVFQRTPN 219 >4IZO-A nrPDB Length = 419 Score = 32.6 bits (73), Expect = 0.31, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 27/69 (39%), Gaps = 9/69 (13%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQV---------QHLSD 199 G LG++G G +G A+++G V D + P G L++ Sbjct: 33 LPGAWLGMVGGGQLGRMFCFAAQAMGYRVAVLDPDPTSPAGAVADKHLRAAYDDEAALAE 92 Query: 200 LLNMSDVVS 208 L + D VS Sbjct: 93 LAQLCDAVS 101 >3UF0-A nrPDB Length = 273 Score = 32.6 bits (73), Expect = 0.33, Method: Composition-based stats. Identities = 18/107 (16%), Positives = 38/107 (35%), Gaps = 11/107 (10%) Query: 141 KLAAGSFEARGKKLGIIGYGH-IGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSD 199 + G F G+ + G G IG + G +V + G ++D Sbjct: 21 QSMTGPFSLAGRTAVVTGAGSGIGRAIAHGYARAGAHVLAWGRT----DGVKEVADEIAD 76 Query: 200 LLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLIN----ASRGT 242 ++ V + + N+ A+E++ + +L+N +R Sbjct: 77 GGGSAEAVVADLADLEGAANV--AEELAATRRVDVLVNNAGIIARAP 121 >6ER9-A nrPDB Length = 549 Score = 32.6 bits (73), Expect = 0.34, Method: Composition-based stats. Identities = 8/30 (26%), Positives = 12/30 (40%) Query: 143 AAGSFEARGKKLGIIGYGHIGTQLGILAES 172 GK++G+IG G G Q+ Sbjct: 171 WPEGKNLAGKRVGVIGTGSTGQQVITALAP 200 >2BC1-A nrPDB Length = 490 Score = 32.6 bits (73), Expect = 0.35, Method: Composition-based stats. Identities = 25/121 (20%), Positives = 44/121 (36%), Gaps = 39/121 (32%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNM-------- 203 K++ ++G G+IG +L + G V D+ + G + L+DL+ Sbjct: 195 KRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDR--DLTDLMAKNMEEHGIQ 252 Query: 204 ---------------------------SDVVSLHVPENPSTKNMMGAKEISLMKPGSLLI 236 D+V L V P+T +G +I L + G+ L+ Sbjct: 253 LAFGETVKEVAGNGKVEKIITDKNEYDVDMVILAVGFRPNTT--LGNGKIDLFRNGAFLV 310 Query: 237 N 237 N Sbjct: 311 N 311 >2UYY-A nrPDB Length = 316 Score = 32.6 bits (73), Expect = 0.36, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 29/68 (42%), Gaps = 4/68 (5%) Query: 143 AAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKL----PLGNATQVQHLS 198 + GS KK+G +G G +G+ + +G V ++ + A + + Sbjct: 22 SMGSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGARLGRTPA 81 Query: 199 DLLNMSDV 206 ++++ D+ Sbjct: 82 EVVSTCDI 89 >1BW9-B nrPDB Length = 356 Score = 32.6 bits (73), Expect = 0.36, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 23/64 (35%), Gaps = 4/64 (6%) Query: 148 EARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKL---PLGNATQVQHLSDLLNM- 203 G + + G G +G L LA G + D + + + L D+L+ Sbjct: 173 SLDGLTVLVQGLGAVGGSLASLAAEAGAQLLVADTDTERVAHAVALGHTAVALEDVLSTP 232 Query: 204 SDVV 207 DV Sbjct: 233 CDVF 236 >2HJR-A nrPDB Length = 328 Score = 32.2 bits (72), Expect = 0.37, Method: Composition-based stats. Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 18/75 (24%) Query: 152 KKLGIIGYGHIGTQLGILA--ESLGMYVYFYDIENKLPLGNATQVQHLSDL--------- 200 KK+ IIG G IG+ + +L + LG VY +DI +P G A + H L Sbjct: 15 KKISIIGAGQIGSTIALLLGQKDLG-DVYMFDIIEGVPQGKALDLNHCMALIGSPAKIFG 73 Query: 201 ------LNMSDVVSL 209 L SDVV + Sbjct: 74 ENNYEYLQNSDVVII 88 >4DLL-A nrPDB Length = 320 Score = 32.2 bits (72), Expect = 0.38, Method: Composition-based stats. Identities = 18/123 (14%), Positives = 40/123 (32%), Gaps = 7/123 (5%) Query: 148 EARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVV 207 + +K+ +G G +G + G + ++ A + + + Sbjct: 28 DPYARKITFLGTGSMGLPMARRLCEAGYALQVWNRTPARAASLAALGATIHEQARAAARD 87 Query: 208 SLHVPENPSTKNMMGAKEISL-----MKPGSLLINASRGTVVDIPALCDALASKHLAGAA 262 + V ++ + MKPGSL ++ + ++ A A L A Sbjct: 88 ADIVVSMLENGAVVQDVLFAQGVAAAMKPGSLFLDMA--SITPREARDHAARLGALGIAH 145 Query: 263 IDV 265 +D Sbjct: 146 LDT 148 >4RG3-A nrPDB Length = 548 Score = 32.2 bits (72), Expect = 0.40, Method: Composition-based stats. Identities = 7/30 (23%), Positives = 12/30 (40%) Query: 143 AAGSFEARGKKLGIIGYGHIGTQLGILAES 172 G+++G+IG G G Q+ Sbjct: 178 WPEGKSLAGRRVGVIGTGSTGQQVITSLAP 207 >5T5Q-A nrPDB Length = 247 Score = 32.2 bits (72), Expect = 0.41, Method: Composition-based stats. Identities = 12/65 (18%), Positives = 24/65 (36%), Gaps = 2/65 (3%) Query: 143 AAGSFEARGKKLGIIGY-GHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLL 201 + FE + L + G G IG + L + G + D++ + A + + Sbjct: 1 GSMKFEFENRTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSPERIA 60 Query: 202 N-MSD 205 +D Sbjct: 61 TIKAD 65 >5Y77-A nrPDB Length = 473 Score = 32.2 bits (72), Expect = 0.42, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 21/52 (40%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNM 203 +++ IIG G GT + L G V ++ + + + ++ L Sbjct: 9 RQVTIIGAGLAGTLVARLLARNGWQVNLFERRPDPRIETGARGRSINLALAE 60 >4K28-A nrPDB Length = 269 Score = 32.2 bits (72), Expect = 0.45, Method: Composition-based stats. Identities = 22/107 (20%), Positives = 39/107 (36%), Gaps = 20/107 (18%) Query: 145 GSFEARGKKLGIIGYGHIGTQLGILAESLG-MYVYFYDIENK-------------LPLGN 190 FE GK+ +IG G +G+ + G + D L Sbjct: 119 HGFEPAGKRALVIGCGGVGSAIAYALAEAGIASITLCDPSTARMGAVCELLGNGFPGLTV 178 Query: 191 ATQVQHLSDLLNMSDVVSLHVPENPSTKNM--MGAKEISLMKPGSLL 235 +TQ L D D+V+ P T+ + A ++ ++P +L+ Sbjct: 179 STQFSGLEDF----DLVANASPVGMGTRAELPLSAALLATLQPDTLV 221 >1CF2-P nrPDB Length = 337 Score = 32.2 bits (72), Expect = 0.45, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 39/108 (36%), Gaps = 31/108 (28%) Query: 152 KKLGIIGYGHIGTQLGI-LAESLGMYVYFY-----DIENKLPLGNATQ------------ 193 K + I GYG +G ++ +A+ M V D E ++ L Sbjct: 2 KAVAINGYGTVGKRVADAIAQQDDMKVIGVSKTRPDFEARMALKKGYDLYVAIPERVKLF 61 Query: 194 -------VQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSL 234 + D+L+ +D+V PE +GAK + + K + Sbjct: 62 EKAGIEVAGTVDDMLDEADIVIDCTPEG------IGAKNLKMYKEKGI 103 >4XGI-A nrPDB Length = 436 Score = 32.2 bits (72), Expect = 0.45, Method: Composition-based stats. Identities = 8/34 (23%), Positives = 15/34 (44%) Query: 146 SFEARGKKLGIIGYGHIGTQLGILAESLGMYVYF 179 E G ++ + G+G++G L + G V Sbjct: 226 GVEIEGARIAVQGFGNVGGIAAKLFQEAGAKVIA 259 >6BZ0-A nrPDB Length = 480 Score = 31.8 bits (71), Expect = 0.48, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 30/76 (39%), Gaps = 19/76 (25%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHV 211 K+LG+IG G IG +LG + LG V + + + L M+D Sbjct: 184 KRLGVIGAGVIGLELGSVWRRLGAEVVVF--------------EAMDAFLPMAD-----K 224 Query: 212 PENPSTKNMMGAKEIS 227 + + ++ + + Sbjct: 225 ALSKEYQKILTKQGLD 240 >3L8K-A nrPDB Length = 466 Score = 31.8 bits (71), Expect = 0.49, Method: Composition-based stats. Identities = 32/195 (16%), Positives = 64/195 (32%), Gaps = 34/195 (17%) Query: 156 IIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQ--VQHLSDLLNMSDVVSLHVPE 213 IIG G+IG ++ + +G+ + ++ ++ + Q V L +L ++ + + P Sbjct: 177 IIGAGYIGLEIASIFRLMGVQTHIIEMLDRALITLEDQDIVNTLLSILKLN--IKFNSPV 234 Query: 214 NPSTKNMMGA--KEISLMKPG---SLLIN-----ASRGTVVDIPALCDALASKHLAGAAI 263 K + + I K G S+ N A R V+ A L+ Sbjct: 235 T-EVKKIKDDEYEVIYSTKDGSKKSIFTNSVVLAAGRRPVIPEGAREIGLSISKTGIVV- 292 Query: 264 DVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGST--QEAQENIGLEVAGKLIKYSDNGST 321 + NV T G A + + A + NG Sbjct: 293 -------------DETMKTNIPNVFATGDANGLAPYYHAAVRMSIAAANNI---MANGMP 336 Query: 322 LSAVNFPEVSLPLHG 336 + V+ + + ++ Sbjct: 337 VDYVDVKSIPVTIYT 351 >1E3J-A nrPDB Length = 352 Score = 31.8 bits (71), Expect = 0.51, Method: Composition-based stats. Identities = 9/38 (23%), Positives = 16/38 (42%) Query: 151 GKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPL 188 G + +IG G IG + A++ G +V + Sbjct: 169 GTTVLVIGAGPIGLVSVLAAKAYGAFVVCTARSPRRLE 206 >4DLA-A nrPDB Length = 396 Score = 31.8 bits (71), Expect = 0.51, Method: Composition-based stats. Identities = 9/37 (24%), Positives = 18/37 (48%), Gaps = 1/37 (2%) Query: 151 GKKLGIIGYGHIGTQLGILAESLGM-YVYFYDIENKL 186 G + + G G +G + A++ G + DI++K Sbjct: 212 GSIVAVFGLGTVGLAVAEGAKAAGASRIIGIDIDSKK 248 >3VTF-A nrPDB Length = 444 Score = 31.8 bits (71), Expect = 0.54, Method: Composition-based stats. Identities = 21/119 (17%), Positives = 40/119 (33%), Gaps = 16/119 (13%) Query: 117 IGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYG----------HIGTQL 166 +G + + + V N R L RG+ +G++G G ++ Sbjct: 299 LGLEMAISKAVLRVNEYMPRYAVQLLEERLGGLRGRHVGVLGLAFKPNTDDVRESRGVEV 358 Query: 167 GILAESLGMYVYFYDI-----ENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNM 220 L G VY +D + + T V+ LL+ + V + P + + Sbjct: 359 ARLLLERGARVYVHDPMAMEKARAVLGDSVTYVEDPQALLDQVEGVIIATA-WPQYEGL 416 >3H9E-O nrPDB Length = 346 Score = 31.8 bits (71), Expect = 0.55, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 14/31 (45%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYF 179 AR +GI G+G IG + G+ V Sbjct: 5 ARELTVGINGFGRIGRLVLRACMEKGVKVVA 35 >6B4O-A nrPDB Length = 452 Score = 31.8 bits (71), Expect = 0.59, Method: Composition-based stats. Identities = 16/121 (13%), Positives = 38/121 (31%), Gaps = 21/121 (17%) Query: 143 AAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLN 202 + E K++ +G G+I +L LG + + ++ PL + D+L+ Sbjct: 161 GFFALEEMPKRVVFVGAGYIAAELAGTLHGLGAETH-WAFRHERPL------RSFDDMLS 213 Query: 203 MS----------DVVSLHVPE----NPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPA 248 + P + ++ + + +++ R D Sbjct: 214 EKVVERYQEMGMQIHPNATPAKIEKTAQNEYVITFENGESITTDAVIFGTGRQPNTDQLG 273 Query: 249 L 249 L Sbjct: 274 L 274 >1EUZ-A nrPDB Length = 419 Score = 31.5 bits (70), Expect = 0.63, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 20/46 (43%), Gaps = 1/46 (2%) Query: 140 NKLAAGSFEARGKKLGIIGYGHIGTQLGILAE-SLGMYVYFYDIEN 184 A + +GKK+ + GYG+ G LA+ LGM V Sbjct: 201 EAAKALGIDLKGKKIAVQGYGNAGYYTAKLAKEQLGMTVVAVSDSR 246 >1VC2-A nrPDB Length = 331 Score = 31.5 bits (70), Expect = 0.63, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 21/46 (45%), Gaps = 1/46 (2%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYV-YFYDIENKLPLGNATQVQH 196 K+GI G+G IG Q+ + G+ V D+ + L + + Sbjct: 1 MKVGINGFGRIGRQVFRILHERGVEVALINDLTDNKTLAHLLKYDS 46 >4DYD-A nrPDB Length = 283 Score = 31.5 bits (70), Expect = 0.64, Method: Composition-based stats. Identities = 11/56 (19%), Positives = 21/56 (37%), Gaps = 1/56 (1%) Query: 149 ARGKK-LGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNM 203 G + ++G G +G+Q+ G V YDI + + L+ + Sbjct: 1 MTGITNVTVLGTGVLGSQIAFQTAFHGFAVTAYDINTDALDAAKKRFEGLAAVYEK 56 >4E21-A nrPDB Length = 358 Score = 31.5 bits (70), Expect = 0.66, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 24/68 (35%), Gaps = 7/68 (10%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQ----VQHLSDL---LNMS 204 ++G+IG G +G + G YD+ + + + + L Sbjct: 23 MQIGMIGLGRMGADMVRRLRKGGHECVVYDLNVNAVQALEREGIAGARSIEEFCAKLVKP 82 Query: 205 DVVSLHVP 212 VV L VP Sbjct: 83 RVVWLMVP 90 >3OJO-A nrPDB Length = 431 Score = 31.5 bits (70), Expect = 0.72, Method: Composition-based stats. Identities = 48/262 (18%), Positives = 78/262 (29%), Gaps = 81/262 (30%) Query: 151 GKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNA-----TQVQHLSDLLNM-- 203 G KL ++G G+IG I+ G+ V DI + + L ++ Sbjct: 11 GSKLTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKLQNGQISIEEPGLQEVYEEVL 70 Query: 204 -------------SDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALC 250 SDV + VP P+ + DI + Sbjct: 71 SSGKLKVSTTPEASDVFIIAVP-TPN-----NDDQYRS---------------CDISLVM 109 Query: 251 DALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAG 310 AL S P + N ++ + A + + V Sbjct: 110 RALDS----------------------ILPFLKKGNTIIV-----ESTIAPKTMDDFVKP 142 Query: 311 KLIKY-SDNGSTLSAVNFPEVSLPLHGGRRLMHIHENRPGVLTALNKIFAEQGVNIAAQY 369 + G + V+ PE LP L +H NR ++ + K E G + + Sbjct: 143 VIENLGFTIGEDIYLVHCPERVLPGKILEEL--VHNNR--IIGGVTKACIEAGKRVYRTF 198 Query: 370 LQTSAQMGYVVIDIEADEDVAE 391 +Q +M IE D AE Sbjct: 199 VQ--GEM------IETDARTAE 212 >2Z04-A nrPDB Length = 365 Score = 31.5 bits (70), Expect = 0.72, Method: Composition-based stats. Identities = 20/132 (15%), Positives = 44/132 (33%), Gaps = 33/132 (25%) Query: 153 KLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLP----LGNATQVQHLSDLLNMSDVVS 208 +GI+G G +G + LG + + + P + +S+ ++ D++ Sbjct: 3 TVGILGGGQLGWMTILEGRKLGFKFHVLEDKENAPACRVADRCFRTGQISEFVDSCDII- 61 Query: 209 LHVPENPSTKNMMGAKEISLMK------PGSLLINASRGT----------------VVDI 246 ++ + + + + P +L + SR V+ Sbjct: 62 -----TYEFEH-IKDEVLEKCESKLIPNPQALYVKKSRIREKLFLKKHGFPVPEFLVIKR 115 Query: 247 PALCDALASKHL 258 + DAL S L Sbjct: 116 DEIIDALKSFKL 127 >4JJI-A nrPDB Length = 378 Score = 31.5 bits (70), Expect = 0.75, Method: Composition-based stats. Identities = 10/40 (25%), Positives = 18/40 (45%), Gaps = 1/40 (2%) Query: 151 GKKLGIIGYGHIGTQLGILAESLGM-YVYFYDIENKLPLG 189 G + I G G +G + A++ G + DI++K Sbjct: 194 GSNVAIFGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYET 233 >3MJ4-A nrPDB Length = 397 Score = 31.5 bits (70), Expect = 0.79, Method: Composition-based stats. Identities = 11/38 (28%), Positives = 15/38 (39%) Query: 148 EARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENK 185 E++G I+G G G+ L S G V D Sbjct: 26 ESKGFDYLIVGAGFAGSVLAERLASSGQRVLIVDRRPH 63 >1PJB-A nrPDB Length = 361 Score = 31.5 bits (70), Expect = 0.81, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 39/103 (37%), Gaps = 18/103 (17%) Query: 164 TQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLL-----------NMSDVVSLHVP 212 T+ +A LG V +DI + T +LL +D++ V Sbjct: 180 TEAAKMAVGLGAQVQIFDINVERLSYLETLFGSRVELLYSNSAEIETAVAEADLLIGAV- 238 Query: 213 ENPSTKN--MMGAKEISLMKPGSLLINASRGTVVDIPALCDAL 253 P + ++ A + M+ GS++++ + VD + L Sbjct: 239 LVPGRRAPILVPASLVEQMRTGSVIVDVA----VDQGGCVETL 277 >4YRY-B nrPDB Length = 468 Score = 31.1 bits (69), Expect = 0.83, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 20/52 (38%), Gaps = 3/52 (5%) Query: 151 GKKLGIIGYGHIGTQLGILAESLGMY---VYFYDIENKLPLGNATQVQHLSD 199 GKK+ +IG G+ A LG + + E ++P L + Sbjct: 279 GKKVAVIGAGNTAMDAARSALRLGAEKVYIVYRRTEREMPARREEYHHALEE 330 >5C7I-O nrPDB Length = 333 Score = 31.1 bits (69), Expect = 0.87, Method: Composition-based stats. Identities = 8/27 (29%), Positives = 13/27 (48%) Query: 153 KLGIIGYGHIGTQLGILAESLGMYVYF 179 +GI G+G IG + + G+ V Sbjct: 3 TVGINGFGRIGRLVLRVCMEKGIRVVA 29 >6N7L-A nrPDB Length = 353 Score = 31.1 bits (69), Expect = 0.88, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 19/38 (50%) Query: 151 GKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPL 188 G+ + I G G +G A+++GM+V D+ + Sbjct: 177 GEWVAISGIGGLGHVAVQYAKAMGMHVAAIDVADDKLE 214 >6DHM-A nrPDB Length = 582 Score = 31.1 bits (69), Expect = 0.95, Method: Composition-based stats. Identities = 7/75 (9%), Positives = 18/75 (24%), Gaps = 1/75 (1%) Query: 127 VPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIE-NK 185 + + + + K + G+G++G G Sbjct: 301 FHGIENFINEASYMSILGMTPGFGDKTFAVQGFGNVGLHSMRYLHRFGAKCVAVGESDGS 360 Query: 186 LPLGNATQVQHLSDL 200 + + + L D Sbjct: 361 IWNPDGIDPKELEDF 375 >4DIO-A nrPDB Length = 405 Score = 31.1 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 21/143 (14%), Positives = 46/143 (32%), Gaps = 40/143 (27%) Query: 156 IIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNA------------------------ 191 ++G G G Q A LG V D+ A Sbjct: 195 VMGAGVAGLQAIATARRLGAVVSATDVRPAAKEQVASLGAKFIAVEDEEFKAAETAGGYA 254 Query: 192 ---------TQVQHLSDLLNMSDVV--SLHVPENPSTKNMMGAKEISLMKPGSLLINASR 240 Q +++ + D+V + +P P+ + ++ + + MKPGS++++ + Sbjct: 255 KEMSGEYQVKQAALVAEHIAKQDIVITTALIPGRPAPR-LVTREMLDSMKPGSVVVDLA- 312 Query: 241 GTVVDIPALCDALASKHLAGAAI 263 V+ + + + Sbjct: 313 ---VERGGNIEGAEAGKVTEVGG 332 >3MWB-A nrPDB Length = 313 Score = 31.1 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 5/67 (7%) Query: 331 SLPLHGG----RRLMHIHENRPGVLTALNKIFAEQGVNIAAQYLQTSAQ-MGYVVIDIEA 385 +LP G ++ + E+ PG L + FA +GVN++ + + Q +G+ I+A Sbjct: 192 ALPERTGADKTTVVVPLPEDHPGALMEILDQFASRGVNLSRIESRPTGQYLGHYFFSIDA 251 Query: 386 DEDVAEK 392 D + Sbjct: 252 DGHATDS 258 >1BG6-A nrPDB Length = 359 Score = 31.1 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 25/83 (30%), Gaps = 19/83 (22%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKL-----------PLGNATQVQHL 197 K ++G G+ G G V +DI+ + G Sbjct: 2 IESKTYAVLGLGNGGHAFAAYLALKGQSVLAWDIDAQRIKEIQDRGAIIAEGPGLAGTAH 61 Query: 198 SDLL--------NMSDVVSLHVP 212 DLL +DV+ + VP Sbjct: 62 PDLLTSDIGLAVKDADVILIVVP 84 >4GBJ-A nrPDB Length = 297 Score = 31.1 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 11/89 (12%), Positives = 36/89 (40%), Gaps = 4/89 (4%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLG----NATQVQHLSDLLNMSDVV 207 +K+ +G G++GT + + G + ++ AT V++ D + +V Sbjct: 6 EKIAFLGLGNLGTPIAEILLEAGYELVVWNRTASKAEPLTKLGATVVENAIDAITPGGIV 65 Query: 208 SLHVPENPSTKNMMGAKEISLMKPGSLLI 236 + ++ + + + + + + + + Sbjct: 66 FSVLADDAAVEELFSMELVEKLGKDGVHV 94 >3WTC-A nrPDB Length = 262 Score = 30.7 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 11/51 (21%), Positives = 18/51 (35%), Gaps = 1/51 (1%) Query: 148 EARGKKLGIIGYGH-IGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHL 197 GK + G IG + + G V D++ A +V+ L Sbjct: 5 SLSGKIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEAL 55 >6DU7-A nrPDB Length = 448 Score = 30.7 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 7/45 (15%), Positives = 20/45 (44%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQH 196 + + I+G G+I +L + + G+ + ++ G + + Sbjct: 167 ESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVE 211 >2X41-A nrPDB Length = 721 Score = 30.7 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 7/36 (19%), Positives = 15/36 (41%), Gaps = 2/36 (5%) Query: 229 MKPGSLLINASRGTVVDIPALCDALASKHLAGAAID 264 M + +N R ++ + +AL L+ +D Sbjct: 261 MPGKAYQVNTERRDEIEE--IMEALKEGKLSEEVLD 294 >1ZCJ-A nrPDB Length = 463 Score = 30.7 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 22/112 (19%), Positives = 41/112 (36%), Gaps = 26/112 (23%) Query: 154 LGIIGYGHIGTQLGILAESLGMYVYFYDIENKL-------------------------PL 188 +G++G G +G + I +G+ V + + K Sbjct: 40 VGVLGLGTMGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQASA 99 Query: 189 GNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLI-NAS 239 + + L+ D+V V E+ + K + A+ +L KPG+ L N S Sbjct: 100 KPKLRFSSSTKELSTVDLVVEAVFEDMNLKKKVFAELSALCKPGAFLCTNTS 151 >1L1F-A nrPDB Length = 505 Score = 30.3 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 10/85 (11%), Positives = 22/85 (25%), Gaps = 2/85 (2%) Query: 118 GELLLLLRG-VPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMY 176 G + RG + + + + K + G+G++G G Sbjct: 214 GRISATGRGVFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAK 273 Query: 177 VYFYDIE-NKLPLGNATQVQHLSDL 200 + + + L D Sbjct: 274 CIAVGESDGSIWNPDGIDPKELEDF 298 >3PEF-A nrPDB Length = 287 Score = 30.3 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 16/40 (40%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNA 191 +K G IG G +G+ + G V ++ + A Sbjct: 2 QKFGFIGLGIMGSAMAKNLVKAGCSVTIWNRSPEKAEELA 41 >1DOH-A nrPDB Length = 283 Score = 30.3 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 11/58 (18%), Positives = 18/58 (31%), Gaps = 2/58 (3%) Query: 141 KLAAGSFEARGKKLGIIGYGH-IGTQLGILAESLGMYVYF-YDIENKLPLGNATQVQH 196 L S GK + G G IG ++ + G V Y + ++ Sbjct: 19 PLGPQSASLEGKVALVTGAGRGIGREMAMELGRRGCKVIVNYANSTESAEEVVAAIKK 76 >6IHE-A nrPDB Length = 303 Score = 30.3 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 15/46 (32%), Positives = 21/46 (45%), Gaps = 2/46 (4%) Query: 153 KLGIIGYGHIGTQLGILAESLGM--YVYFYDIENKLPLGNATQVQH 196 K+G IG G IG + A G YDI +LP +++H Sbjct: 2 KVGFIGAGKIGQTIAYSALVSGAVDEAVIYDIIPELPDKFEHELRH 47 >2FGC-A nrPDB Length = 193 Score = 30.3 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 17/55 (30%), Positives = 31/55 (56%), Gaps = 3/55 (5%) Query: 341 MHIHENRPGVLTALNKIFAEQGVNIAAQYLQTSAQMGY--VVIDIEADEDVAEKA 393 M +H N+PGV+ + +FA +G NI++ + S G +VI ++ D+ E+ Sbjct: 34 MLVH-NKPGVMRKVANLFARRGFNISSITVGESETPGLSRLVIMVKGDDKTIEQI 87 >3RWB-A nrPDB Length = 247 Score = 30.3 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 12/35 (34%), Gaps = 1/35 (2%) Query: 149 ARGKKLGIIGYGH-IGTQLGILAESLGMYVYFYDI 182 GK + G IG + + G V DI Sbjct: 4 LAGKTALVTGAAQGIGKAIAARLAADGATVIVSDI 38 >3ZWA-A nrPDB Length = 742 Score = 30.3 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 22/112 (19%), Positives = 41/112 (36%), Gaps = 26/112 (23%) Query: 154 LGIIGYGHIGTQLGILAESLGMYVYFYDIENKL-------------------------PL 188 +G++G G +G + I +G+ V + + K Sbjct: 319 VGVLGLGTMGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQASA 378 Query: 189 GNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLI-NAS 239 + + L+ D+V V E+ + K + A+ +L KPG+ L N S Sbjct: 379 KPKLRFSSSTKELSTVDLVVEAVFEDMNLKKKVFAELSALCKPGAFLCTNTS 430 >3EZY-A nrPDB Length = 344 Score = 30.3 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 31/74 (41%), Gaps = 8/74 (10%) Query: 153 KLGIIGYGHIGTQLGILAESLGMYVYF--YDIEN------KLPLGNATQVQHLSDLLNMS 204 ++G+IG G IGT + + + + D+ K LG + +L+ Sbjct: 4 RIGVIGLGRIGTIHAENLKMIDDAILYAISDVREDRLREMKEKLGVEKAYKDPHELIEDP 63 Query: 205 DVVSLHVPENPSTK 218 +V ++ V + +T Sbjct: 64 NVDAVLVCSSTNTH 77 >4OH1-A nrPDB Length = 351 Score = 30.3 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 17/40 (42%), Gaps = 1/40 (2%) Query: 150 RGKKLGIIGYGHIGTQLGILAESLGMYVY-FYDIENKLPL 188 GK + I+G G +G L LA G +DI + Sbjct: 173 YGKSVAIMGAGGLGMMLVQLARLAGASTITVFDIVPEKLE 212 >1JAY-A nrPDB Length = 212 Score = 30.3 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 15/101 (14%), Positives = 37/101 (36%), Gaps = 20/101 (19%) Query: 158 GYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHL-----------SDLLNMSDV 206 G G++G L + +LG + + A + + + D D+ Sbjct: 8 GTGNLGKGLALRLATLGHEIVVGSRREEKAEAKAAEYRRIAGDASITGMKNEDAAEACDI 67 Query: 207 VSLHVPENPSTKNMMG-AKEISLMKPGSLLIN----ASRGT 242 L +P ++ + A+++ + ++++ SRG Sbjct: 68 AVLTIPW----EHAIDTARDLKNILREKIVVSPLVPVSRGA 104 >1HYH-A nrPDB Length = 309 Score = 29.9 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 22/50 (44%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLL 201 +K+GIIG G++G + + G+ + I+ A Q+ + Sbjct: 2 RKIGIIGLGNVGAAVAHGLIAQGVADDYVFIDANEAKVKADQIDFQDAMA 51 >5T57-A nrPDB Length = 296 Score = 29.9 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 35/89 (39%), Gaps = 7/89 (7%) Query: 152 KKLGIIGYG-HIGTQLGILAESLGMYVYFYDIE----NKLPLGNATQVQHLSDLLNMSDV 206 +K+ + G G +G +L V ++ +L + L+ DV Sbjct: 23 EKIALFGAGGKMGVRLAKNLLKSDYRVSHVEVSEVGKKRLKDELGLECVSTEAALDNVDV 82 Query: 207 VSLHVPENPSTKNMMGAKEISLMKPGSLL 235 V L VP+ + A+ ++PG+++ Sbjct: 83 VILAVPDT--IIGKIAAQIAPQLRPGTMV 109 >4DBZ-A nrPDB Length = 281 Score = 29.9 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 31/78 (39%), Gaps = 4/78 (5%) Query: 162 IGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMM 221 IG ++ G+ V+ + G T ++ L + +D + V P + ++ Sbjct: 38 IGLEIARRLGKEGLRVFVC---ARGEEGLRTTLKELREAGVEADGRTCDVRSVPEIEALV 94 Query: 222 GAKEISLMKPGSLLINAS 239 A + P +L+N + Sbjct: 95 -AAVVERYGPVDVLVNNA 111 >3K8Z-A nrPDB Length = 423 Score = 29.9 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 7/35 (20%), Positives = 15/35 (42%) Query: 145 GSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYF 179 + +G ++ + G+G+ G+ L G V Sbjct: 214 RGIDIKGARVVVQGFGNAGSYLAKFMHDAGAKVVG 248 >1GEU-A nrPDB Length = 450 Score = 29.9 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 8/29 (27%), Positives = 18/29 (62%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFY 180 +++ ++G G+IG +LG + LG + + Sbjct: 168 ERVAVVGAGYIGVELGGVINGLGAKTHLF 196 >1AE1-A nrPDB Length = 273 Score = 29.9 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 10/47 (21%), Positives = 14/47 (29%), Gaps = 1/47 (2%) Query: 144 AGSFEARGKKLGIIGYGH-IGTQLGILAESLGMYVYFYDIENKLPLG 189 G + +G + G IG + LG VY K Sbjct: 14 EGRWSLKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDE 60 >5J9G-A nrPDB Length = 338 Score = 29.9 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 25/72 (34%), Gaps = 14/72 (19%) Query: 153 KLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVP 212 K+GI G+G IG LG +V ++DL + + H+ Sbjct: 4 KIGINGFGRIGRLAFRRIMDLG------------EKSKDIEVVAINDLTTPA--LLAHLL 49 Query: 213 ENPSTKNMMGAK 224 + ST + Sbjct: 50 KYDSTHGTFDHE 61 >2DC1-A nrPDB Length = 236 Score = 29.9 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 23/100 (23%), Positives = 38/100 (38%), Gaps = 11/100 (11%) Query: 154 LGIIGYGHIGTQLGILAESLGMYVYF-YDIENKLPLGNATQVQHLSDLL-NMSDVVSLHV 211 +G+IGYG IG L E G + D+ + + V+ + + L DV Sbjct: 3 VGLIGYGAIGKFLAEWLERNGFEIAAILDVRGE----HEKMVRGIDEFLQREMDVAV--- 55 Query: 212 PENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALCD 251 +++ + ++K G LI S G D L Sbjct: 56 --EAASQQAVKDYAEKILKAGIDLIVLSTGAFADRDFLSR 93 >4J0E-A nrPDB Length = 320 Score = 29.9 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 24/67 (35%), Gaps = 9/67 (13%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLL---------N 202 + + I+G G +G+ + + S G V D+ K + L Sbjct: 15 RNVAIVGSGQMGSGIAQVTASSGFNVMLADVNKKALDRAMKAISQSVTHLSKKQKGTDKE 74 Query: 203 MSDVVSL 209 SD V+L Sbjct: 75 KSDFVTL 81 >4B3J-A nrPDB Length = 736 Score = 29.9 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 9/47 (19%), Positives = 20/47 (42%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLS 198 K++G++G G +G + ++ G V D+ + + L Sbjct: 342 KRIGVLGAGMMGAGIAYVSAKAGYEVVLKDVSLEAAAKGKGYSEKLE 388 >4A7P-A nrPDB Length = 446 Score = 29.9 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 29/86 (33%), Gaps = 11/86 (12%) Query: 131 NAKAHRGVWNKLAAGSFEARGKKLGIIGY----------GHIGTQLGILAESLGMYVYFY 180 +A+ + A + RGK +GI+G + + G V Y Sbjct: 302 DARKRAMGRKVIKAMGGDVRGKTVGILGLTFKPNTDDMRDAPSLSIIAALQDAGATVKAY 361 Query: 181 DIEN-KLPLGNATQVQHLSDLLNMSD 205 D E + T V+ + + +D Sbjct: 362 DPEGVEQASKMLTDVEFVENPYAAAD 387 >3D3W-A nrPDB Length = 244 Score = 29.9 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 9/57 (15%), Positives = 15/57 (26%), Gaps = 11/57 (19%) Query: 149 ARGKKLGIIGYGH-IGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMS 204 G+++ + G G IG + G V L L+ Sbjct: 5 LAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQ----------ADLDSLVREC 51 >5U8W-A nrPDB Length = 481 Score = 29.9 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 14/54 (25%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSD 205 KKLG+IG G IG +LG + LG V ++ L L +D Sbjct: 185 KKLGVIGAGVIGLELGSVWARLGAEVTV--------------LEALDKFLPAAD 224 >5U1O-A nrPDB Length = 458 Score = 29.5 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 9/61 (14%), Positives = 29/61 (47%), Gaps = 2/61 (3%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLG-NATQVQHLSDLLNMSDVVSLH 210 K++ ++G G+I ++ + +LG + + + + + L +++ ++ +LH Sbjct: 175 KRVAVVGAGYIAVEIAGVLHALGTETHLFVRKESPLRSFDPMIIDTLVEVM-EAEGPTLH 233 Query: 211 V 211 Sbjct: 234 T 234 >3E5R-O nrPDB Length = 337 Score = 29.5 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 8/18 (44%), Positives = 12/18 (66%) Query: 153 KLGIIGYGHIGTQLGILA 170 K+GI G+G IG + +A Sbjct: 5 KIGINGFGRIGRLVARVA 22 >5TR3-A nrPDB Length = 481 Score = 29.5 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 16/54 (29%), Positives = 23/54 (42%), Gaps = 14/54 (25%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSD 205 K+LG+IG G IG +LG + LG V ++ L L +D Sbjct: 185 KRLGVIGAGVIGLELGSVWARLGAEVTV--------------LEALDTFLMAAD 224 >3VB0-A nrPDB Length = 294 Score = 29.5 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 31/82 (37%), Gaps = 17/82 (20%) Query: 155 GIIGYGHIGTQLGILAE--SLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVP 212 GI G GH+ + A+ S V + + +++ +D+ LH Sbjct: 141 GIFGLGHLVVIVADRAKTQSFFTDVLGFGLSDRVT-------------WPEADIFFLHCN 187 Query: 213 ENPSTKNMMGAKEISLMKPGSL 234 + T + A + +KPG + Sbjct: 188 QRHHTVAL-SAPALG-LKPGMV 207 >5YX3-A nrPDB Length = 231 Score = 29.5 bits (65), Expect = 3.1, Method: Composition-based stats. Identities = 43/216 (19%), Positives = 72/216 (33%), Gaps = 37/216 (17%) Query: 208 SLHVPENPSTKNMMGAKEISLMKPGSLLIN-ASRGTVVDIPALCDALASKHLAGAAIDVF 266 SL P + + + + M+ G I + G + A ALA K AG A D Sbjct: 15 SLARPPGSAHSHFLAGAGVRGMEIGGNFIKFTAIGVYLQADAAVSALAKKW-AGKAADEL 73 Query: 267 PTEPATNSDPFTSPLCEFDNV-LLTPHIGGSTQE--------------AQENIGLEVAGK 311 ++ A D T +F V ++ P G E A + K Sbjct: 74 ASDAAFFRDVVTGEFEKFTQVTMILPLTGAQYSEKVTENCVAYWKAVGAYTDAEAAAVDK 133 Query: 312 LIKYSDNGSTLSAVNF---------------PEVSLPLHGGRRLMHIHENRPGVLTALNK 356 + + + S+P GG + ENRP L Sbjct: 134 FKEAFKTETFPPGASILFTHSPAGVLTVAFSKNSSVPESGGAAI----ENRPLCEAVLES 189 Query: 357 IFAEQGVNIAAQYLQTSAQMGYVVIDIEADEDVAEK 392 I E GV+ AA+ L + ++ ++ + + ++ A Sbjct: 190 IIGEHGVSPAAK-LSLATRVAELLKEAASVDEPAAA 224 >2VYN-D nrPDB Length = 334 Score = 29.2 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 9/27 (33%), Positives = 14/27 (51%) Query: 153 KLGIIGYGHIGTQLGILAESLGMYVYF 179 K+GI G+G IG + + G+ V Sbjct: 3 KVGINGFGRIGRLVLRVCMEKGVRVVA 29 >3DOJ-A nrPDB Length = 310 Score = 29.2 bits (64), Expect = 3.2, Method: Composition-based stats. Identities = 8/57 (14%), Positives = 24/57 (42%), Gaps = 4/57 (7%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIE----NKLPLGNATQVQHLSDLLNMS 204 ++G +G G +G + + G V ++ ++L A+ + ++++ Sbjct: 22 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKC 78 >3VZS-A nrPDB Length = 257 Score = 29.2 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 28/84 (33%), Gaps = 7/84 (8%) Query: 158 GYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVS--LHVPENP 215 G G IGT + G V N + Q D ++ +V + Sbjct: 22 GMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGF----DFIASEGNVADWD 77 Query: 216 STKNMMGAKEISLMKPGSLLINAS 239 STK + S + +LIN + Sbjct: 78 STKTAFDKVK-SEVGEVDVLINNA 100 >3ZHB-A nrPDB Length = 309 Score = 29.2 bits (64), Expect = 3.4, Method: Composition-based stats. Identities = 14/92 (15%), Positives = 34/92 (36%), Gaps = 5/92 (5%) Query: 154 LGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLG----NATQVQHLSDLLNMSDVVSL 209 + +IG G +G L G ++ A +++ + S +V + Sbjct: 22 VTVIGLGLMGQALAGAFLGAGHPTTVWNRTAAKAEPLVARGAKSAGSVAEAVAASPLVVV 81 Query: 210 HVPENPSTKNMMGAKEISLMKPGSLLINASRG 241 V + + ++ + + + G L+N + G Sbjct: 82 CVSDYDAVHALLDPLDGTAL-QGRTLVNLTSG 112 >3NDC-A nrPDB Length = 264 Score = 29.2 bits (64), Expect = 3.4, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 22/46 (47%), Gaps = 5/46 (10%) Query: 220 MMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDV 265 ++ ++ PG+ ++N + ++ A+ D +A H A DV Sbjct: 39 LVPEALLAHCPPGAKIVNTAPMSL---DAIIDTIAEAH--AAGQDV 79 >2EW8-A nrPDB Length = 249 Score = 29.2 bits (64), Expect = 3.4, Method: Composition-based stats. Identities = 15/82 (18%), Positives = 23/82 (28%), Gaps = 6/82 (7%) Query: 158 GYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPST 217 G IG + G + D+ A + L DV P Sbjct: 15 GANGIGRAIAERFAVEGADIAIADLVPAPEAEAAIRNLGRRVLTVKCDV------SQPGD 68 Query: 218 KNMMGAKEISLMKPGSLLINAS 239 G + IS +L+N + Sbjct: 69 VEAFGKQVISTFGRCDILVNNA 90 >1VSU-A nrPDB Length = 359 Score = 29.2 bits (64), Expect = 3.6, Method: Composition-based stats. Identities = 7/16 (43%), Positives = 9/16 (56%) Query: 153 KLGIIGYGHIGTQLGI 168 LGI G+G IG + Sbjct: 24 TLGINGFGRIGRLVLR 39 >3GG2-A nrPDB Length = 450 Score = 29.2 bits (64), Expect = 3.8, Method: Composition-based stats. Identities = 7/35 (20%), Positives = 13/35 (37%) Query: 154 LGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPL 188 + ++G G++G LG V D + Sbjct: 5 IAVVGIGYVGLVSATCFAELGANVRCIDTDRNKIE 39 >3LK7-A nrPDB Length = 451 Score = 29.2 bits (64), Expect = 3.8, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 13/35 (37%) Query: 150 RGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIEN 184 KK+ ++G G L LG V D + Sbjct: 8 ENKKVLVLGLARSGEAAARLLAKLGAIVTVNDGKP 42 >4AP1-A nrPDB Length = 549 Score = 29.2 bits (64), Expect = 3.8, Method: Composition-based stats. Identities = 27/132 (20%), Positives = 42/132 (31%), Gaps = 29/132 (21%) Query: 33 TNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLD 92 + + + D L+ I R T +T V++ E L G D Sbjct: 100 EILAYLEHVADRFDLRRDI--------RFDTRVTSAVLDE-EGLRWTVRTDRG------D 144 Query: 93 AAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEAN-AKAHRGVWNKLAAGSFEARG 151 + R + V P SN + A G+ H W + G Sbjct: 145 EVSARFLVVAAGPLSNANTPA----------FDGLDRFTGDIVHTARW---PHDGVDFTG 191 Query: 152 KKLGIIGYGHIG 163 K++G+IG G G Sbjct: 192 KRVGVIGTGSSG 203 >2O3A-A nrPDB Length = 178 Score = 29.2 bits (64), Expect = 3.9, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 22/63 (34%), Gaps = 12/63 (19%) Query: 161 HIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHL------------SDLLNMSDVVS 208 I T + + A + G ++D E+K + V LL D + Sbjct: 19 RISTHVALTARAFGAKGIYFDTEDKSVFESVRDVVERWGGDFFIKAVSWKKLLREFDGLK 78 Query: 209 LHV 211 +H+ Sbjct: 79 VHL 81 >3O0H-A nrPDB Length = 484 Score = 28.8 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 8/25 (32%), Positives = 14/25 (56%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMY 176 K + I+G G+IG + + LG+ Sbjct: 192 KSIVIVGGGYIGVEFANIFHGLGVK 216 >6HRD-A nrPDB Length = 317 Score = 28.8 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 10/48 (20%), Positives = 24/48 (50%), Gaps = 1/48 (2%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLP-LGNATQVQHLS 198 +++G++G G +G+ + ++ G+ V ++ L G V+ L Sbjct: 26 QRVGVVGAGQMGSGIAEVSARAGVEVTVFEPAEALITAGRNRIVKSLE 73 >4Z0H-O nrPDB Length = 334 Score = 28.8 bits (63), Expect = 4.2, Method: Composition-based stats. Identities = 6/17 (35%), Positives = 11/17 (64%) Query: 153 KLGIIGYGHIGTQLGIL 169 ++GI G+G IG + + Sbjct: 3 RIGINGFGRIGRLVARV 19 >5VDN-A nrPDB Length = 463 Score = 28.8 bits (63), Expect = 4.2, Method: Composition-based stats. Identities = 8/50 (16%), Positives = 24/50 (48%), Gaps = 1/50 (2%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLG-NATQVQHLSDL 200 K++ ++G G+I ++ + LG + + ++ + V+ L ++ Sbjct: 181 KRVAVVGAGYIAVEIAGVLNGLGTETHLFVRKHAPLRTFDPLIVETLLEV 230 >3IHM-A nrPDB Length = 430 Score = 28.8 bits (63), Expect = 4.3, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 18/39 (46%), Gaps = 1/39 (2%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFY-DIENKLPLG 189 K++GI+G G G LG+ + V Y D + G Sbjct: 23 KRIGIVGAGTAGLHLGLFLRQHDVDVTVYTDRKPDEYSG 61 >5VT6-A nrPDB Length = 269 Score = 28.8 bits (63), Expect = 4.4, Method: Composition-based stats. Identities = 9/43 (20%), Positives = 15/43 (34%), Gaps = 2/43 (4%) Query: 137 GVWNKLAAGSFEARGKKLGII--GYGHIGTQLGILAESLGMYV 177 G G + K++ + G G +G + GM V Sbjct: 10 GTLEAQTQGPGSMQAKRVAFVTGGMGGLGAAISRRLHDAGMAV 52 >3PDU-A nrPDB Length = 287 Score = 28.8 bits (63), Expect = 4.6, Method: Composition-based stats. Identities = 9/58 (15%), Positives = 18/58 (31%), Gaps = 4/58 (6%) Query: 153 KLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLG----NATQVQHLSDLLNMSDV 206 G +G G +G + G V ++ A Q +++ D+ Sbjct: 3 TYGFLGLGIMGGPMAANLVRAGFDVTVWNRNPAKCAPLVALGARQASSPAEVCAACDI 60 >4OQY-A nrPDB Length = 290 Score = 28.8 bits (63), Expect = 4.7, Method: Composition-based stats. Identities = 9/64 (14%), Positives = 24/64 (37%), Gaps = 4/64 (6%) Query: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQ----VQHLSDLLNMSDVV 207 + + +IG G +G + G V ++ + + D L+ ++++ Sbjct: 4 QSVTVIGLGPMGQAMVNTFLDNGHEVTVWNRTASKAEALVARGAVLAPTVEDALSANELI 63 Query: 208 SLHV 211 L + Sbjct: 64 VLSL 67 >2DQ4-A nrPDB Length = 343 Score = 28.8 bits (63), Expect = 4.7, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 15/53 (28%) Query: 144 AGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQH 196 GK + I G G IG ++ + G N L A Sbjct: 158 YAGSGVSGKSVLITGAGPIGLMAAMVVRASGAGPILVSDPNPYRLAFARPYAD 210 >2NVK-X nrPDB Length = 488 Score = 28.4 bits (62), Expect = 5.3, Method: Composition-based stats. Identities = 9/24 (37%), Positives = 14/24 (58%), Gaps = 1/24 (4%) Query: 151 GKKLGIIGYGHIGTQLGILAESLG 174 GK L ++G G+IG + + LG Sbjct: 188 GKTL-VVGAGYIGLECAGFLKGLG 210 >2GRA-A nrPDB Length = 277 Score = 28.4 bits (62), Expect = 5.4, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 27/73 (36%), Gaps = 12/73 (16%) Query: 150 RGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDL--------- 200 RG +G IG G + L + G+ + + I P + V L + Sbjct: 1 RGMSVGFIGAGQLAFALAKGFTAAGV-LAAHKIMASSPDMDLATVSALRKMGVKLTPHNK 59 Query: 201 --LNMSDVVSLHV 211 + SDV+ L V Sbjct: 60 ETVQHSDVLFLAV 72 >5TPR-A nrPDB Length = 444 Score = 28.4 bits (62), Expect = 5.5, Method: Composition-based stats. Identities = 21/124 (16%), Positives = 35/124 (28%), Gaps = 23/124 (18%) Query: 20 HQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVINAAEKLVAI 79 HQ+ E L G + H G +D + I LT I+ +L Sbjct: 241 HQEVFELLEKYGEELLRTHFGNIDATPEIKEIAH----------RLTYKAIHKMLELEVP 290 Query: 80 GCFCIGTNQVDLDAAAKRGIPVFNA-------PFSNTRSV-AELVIGELLLLLRGVPEAN 131 ++DLD G P + +V ++ + RG Sbjct: 291 NLH-----ELDLDRVIAYGHTWSPTLELAPRLPMFHGHAVNVDMAFSATIAARRGYITIA 345 Query: 132 AKAH 135 + Sbjct: 346 ERDR 349 >3TR8-A nrPDB Length = 186 Score = 28.4 bits (62), Expect = 5.5, Method: Composition-based stats. Identities = 27/138 (19%), Positives = 48/138 (34%), Gaps = 9/138 (6%) Query: 263 IDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIG-LEVAGKLIKYSDNGST 321 +D+ PA L DN + H E +N EV + + + Sbjct: 40 LDILAEGPAFAIHQPDKLLTAMDNWNTSHHTASGLLERVKNSSVDEVEAETLTLAFLEKY 99 Query: 322 LSAVNFPEVSLPLHGGRRLMHIHENRPGVLTALNKIFAEQGVNIAAQYLQTSAQMGYVVI 381 +SA P + RR + + R LN+ F + +++ L+ AQ I Sbjct: 100 VSAGKSPLCGNSVCQDRRFLSRYMPR------LNQFFHYRHLDVTT--LKILAQRWAPQI 151 Query: 382 DIEADEDVAEKALQAMKA 399 ++ ALQ ++ Sbjct: 152 AAAHIKESQHLALQDIRD 169 >4RZI-B nrPDB Length = 240 Score = 28.4 bits (62), Expect = 5.5, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 21/64 (32%), Gaps = 5/64 (7%) Query: 146 SFEARGKKLGIIGYGH-IGTQLGILAESLGMYV----YFYDIENKLPLGNATQVQHLSDL 200 S K + + G IG + L + +G V D N LG V L + Sbjct: 3 SLGLEDKVIVVTGGNRGIGAAIVKLLQEMGAKVAFTDLATDGGNTEALGVVANVTDLESM 62 Query: 201 LNMS 204 + Sbjct: 63 TAAA 66 >3IC9-A nrPDB Length = 492 Score = 28.4 bits (62), Expect = 5.5, Method: Composition-based stats. Identities = 12/43 (27%), Positives = 18/43 (41%), Gaps = 2/43 (4%) Query: 147 FEARG--KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLP 187 FE K + + G G IG +LG LG+ V + + Sbjct: 168 FELNDLPKSVAVFGPGVIGLELGQALSRLGVIVKVFGRSGSVA 210 >2B4T-O nrPDB Length = 345 Score = 28.4 bits (62), Expect = 5.5, Method: Composition-based stats. Identities = 16/50 (32%), Positives = 20/50 (40%), Gaps = 6/50 (12%) Query: 153 KLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLN 202 KLGI G+G IG + + G DIE + HL LL Sbjct: 13 KLGINGFGRIGRLVFR--AAFGRK----DIEVVAINDPFMDLNHLCYLLK 56 >5ZZ6-A nrPDB Length = 208 Score = 28.4 bits (62), Expect = 5.7, Method: Composition-based stats. Identities = 18/102 (17%), Positives = 37/102 (36%), Gaps = 24/102 (23%) Query: 123 LLRGVPEANAKAHR-----GVWNKLAAGS-----FEARGKKLGI--------IGYGHIGT 164 L R + ++ + G + K G ++A G+ LG+ +G G+IG Sbjct: 36 LARRLDLKASQIRKDLSYFGEFGKRGVGYNVEHLYDAIGEILGVKKEWKLVVVGAGNIGR 95 Query: 165 QLG--ILAESLGMYVYF-YDIENK---LPLGNATQVQHLSDL 200 + + + G + +D + V +S+L Sbjct: 96 AVANYTVMKEKGFRIIGIFDSDPSKIGKEAAPGLTVSDVSEL 137 >3UVE-A nrPDB Length = 286 Score = 28.4 bits (62), Expect = 6.0, Method: Composition-based stats. Identities = 10/64 (15%), Positives = 20/64 (31%), Gaps = 3/64 (4%) Query: 75 KLVAIGCFCIGTNQVDLDAAA--KRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANA 132 + A+ G + + +D + G+ P S +AE + R + A Sbjct: 25 RSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDLAETA-DLVKGHNRRIVTAEV 83 Query: 133 KAHR 136 Sbjct: 84 DVRD 87 >5A9T-A nrPDB Length = 290 Score = 28.4 bits (62), Expect = 6.5, Method: Composition-based stats. Identities = 15/88 (17%), Positives = 36/88 (40%), Gaps = 6/88 (6%) Query: 154 LGIIGYGHIGTQLGILAESLGMYVYFYDIEN----KLPLGNATQVQHLSDLLNMSDVVSL 209 + + G G +G+ L G V ++ L A Q + D ++ S ++ + Sbjct: 8 VTVAGLGPMGSALAAALLDRGHDVTVWNRSPGKAAPLVAKGARQADDIVDAVSASRLLVV 67 Query: 210 HVPENPSTKNMMGAKEISLMKPGSLLIN 237 + + + + +G +L G +++N Sbjct: 68 CLADYDALYSALGPAREAL--RGRVVVN 93 >5VMT-A nrPDB Length = 342 Score = 28.0 bits (61), Expect = 6.9, Method: Composition-based stats. Identities = 17/87 (19%), Positives = 36/87 (41%), Gaps = 24/87 (27%) Query: 153 KLGIIGYGHIGT-QLGILAESLGMYVYFY-DIENKLPLGNATQVQHLSDLLNMSDVVSLH 210 K+ I G+G IG L + ++ G+ V D+ ++L LH Sbjct: 12 KVAINGFGRIGRLALRQIEKAHGIEVAAVNDLTPA-------------EML-------LH 51 Query: 211 VPENPSTKNMMGAKEISLMKPGSLLIN 237 + + ST+ + + +K ++++N Sbjct: 52 LFKYDSTQGRF--QGTAELKDDAIVVN 76 >3L6D-A nrPDB Length = 306 Score = 28.0 bits (61), Expect = 6.9, Method: Composition-based stats. Identities = 9/51 (17%), Positives = 19/51 (37%) Query: 154 LGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMS 204 + +IG G +GT + + G V ++ HL + + + Sbjct: 12 VSVIGLGAMGTIMAQVLLKQGKRVAIWNRSPGKAAALVAAGAHLCESVKAA 62 >3IHG-A nrPDB Length = 535 Score = 28.0 bits (61), Expect = 6.9, Method: Composition-based stats. Identities = 9/65 (13%), Positives = 20/65 (30%) Query: 230 KPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLL 289 G + NA+ D+ A+ +D + E ++ + + Sbjct: 315 PTGGMSGNAAVADGFDLAWKLAAVLQGQAGAGLLDTYEDERKVAAELVVAEALAIYAQRM 374 Query: 290 TPHIG 294 PH+ Sbjct: 375 APHMA 379 >1LLU-A nrPDB Length = 342 Score = 28.0 bits (61), Expect = 6.9, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 19/38 (50%) Query: 151 GKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPL 188 G+ + I G G +G A ++G++V DI++ Sbjct: 171 GQWVAISGIGGLGHVAVQYARAMGLHVAAIDIDDAKLE 208 >2VG4-A nrPDB Length = 284 Score = 28.0 bits (61), Expect = 7.4, Method: Composition-based stats. Identities = 5/41 (12%), Positives = 19/41 (46%) Query: 170 AESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLH 210 + LG+ + + +L ++ ++ +DV++++ Sbjct: 138 LKKLGVRIRWVGSRPRLWRSVINELAVAEEMTKSNDVITIN 178 >5NC8-A nrPDB Length = 237 Score = 28.0 bits (61), Expect = 7.7, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 13/32 (40%) Query: 156 IIGYGHIGTQLGILAESLGMYVYFYDIENKLP 187 I GYG G +G L + G ++ D Sbjct: 32 IAGYGRFGQVVGRLLSAQGYHLSILDHSPSQI 63 >5B37-A nrPDB Length = 361 Score = 28.0 bits (61), Expect = 7.9, Method: Composition-based stats. Identities = 7/42 (16%), Positives = 16/42 (38%) Query: 149 ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGN 190 G K+ + G G++G L + ++ D++ Sbjct: 167 LDGMKVAVQGLGNVGKNLCRHLHEHDVQLFVSDVDPIKAEEV 208 >2HTM-A nrPDB Length = 268 Score = 28.0 bits (61), Expect = 8.1, Method: Composition-based stats. Identities = 26/156 (16%), Positives = 53/156 (33%), Gaps = 22/156 (14%) Query: 129 EANAKAHRGVWNKLAAGSFEAR-GKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLP 187 +A + + L + K+L +G + + G+ L Sbjct: 115 KAAERLIEEDFLVLPYMGPDLVLAKRLAALGTATVMPLAAPIGSGWGV------RTRALL 168 Query: 188 LGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIP 247 A + L ++ + L +P + A E+ + ++L+N + D P Sbjct: 169 ELFAREKASLPPVVVDA---GLGLPSH--------AAEVMELGLDAVLVNTAIAEAQDPP 217 Query: 248 ALCD----ALASKHLAGAAIDVFPTEPATNSDPFTS 279 A+ + A+ + A A + P E A+ S P Sbjct: 218 AMAEAFRLAVEAGRKAYLAGPMRPREAASPSSPVEG 253 >4A5O-A nrPDB Length = 286 Score = 27.6 bits (60), Expect = 9.0, Method: Composition-based stats. Identities = 27/160 (16%), Positives = 56/160 (35%), Gaps = 32/160 (20%) Query: 122 LLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYGHI-GTQLGILAESLGMYVYFY 180 L + +P +G+ LA+ + G ++G +I G + + G V Sbjct: 132 RLAQRMPLLRPCTPKGIMTLLASTGADLYGMDAVVVGASNIVGRPMALELLLGGCTVTVT 191 Query: 181 DIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASR 240 + L+D ++ +D+V + ++ + I K G+++I+ Sbjct: 192 HRFTR----------DLADHVSRADLVVVA----AGKPGLVKGEWI---KEGAIVIDVG- 233 Query: 241 GTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSP 280 ++ A L G DV E A + +P Sbjct: 234 ---INRQA------DGRLVG---DV-EYEVAAQRASWITP 260 >6F8L-G nrPDB Length = 913 Score = 27.6 bits (60), Expect = 9.1, Method: Composition-based stats. Identities = 15/82 (18%), Positives = 26/82 (31%), Gaps = 10/82 (12%) Query: 255 SKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIK 314 K L A +D + L V GGS E ++GL ++ + Sbjct: 8 DKRLGAALLDA----GLLTDEELQRALERHREV------GGSLAEVLVDMGLLSERRIAQ 57 Query: 315 YSDNGSTLSAVNFPEVSLPLHG 336 ++ + V V +P Sbjct: 58 TIEDRFGIPLVELHRVEIPPKV 79 >3GRP-A nrPDB Length = 266 Score = 27.6 bits (60), Expect = 9.4, Method: Composition-based stats. Identities = 10/55 (18%), Positives = 18/55 (32%), Gaps = 1/55 (1%) Query: 141 KLAAGSFEARGKKLGIIG-YGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQV 194 + F+ G+K + G G IG + + G V + A + Sbjct: 17 QGPGSMFKLTGRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADL 71 >3DWF-A nrPDB Length = 276 Score = 27.6 bits (60), Expect = 9.4, Method: Composition-based stats. Identities = 9/50 (18%), Positives = 18/50 (36%), Gaps = 1/50 (2%) Query: 149 ARGKKLGIIGYGH-IGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHL 197 +GKK+ + G IG ++ +G +V + + L Sbjct: 9 LQGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLEL 58 >4CQL-A nrPDB Length = 261 Score = 27.6 bits (60), Expect = 9.5, Method: Composition-based stats. Identities = 7/35 (20%), Positives = 12/35 (34%), Gaps = 1/35 (2%) Query: 156 IIGYGH-IGTQLGILAESLGMYVYFYDIENKLPLG 189 + G G IG + + G V D++ Sbjct: 16 VTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQE 50 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.145 0.387 Lambda K H 0.267 0.0443 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,827,673 Number of Sequences: 36641 Number of extensions: 671423 Number of successful extensions: 3361 Number of sequences better than 10.0: 331 Number of HSP's better than 10.0 without gapping: 285 Number of HSP's successfully gapped in prelim test: 144 Number of HSP's that attempted gapping in prelim test: 2660 Number of HSP's gapped (non-prelim): 480 length of query: 410 length of database: 10,336,785 effective HSP length: 99 effective length of query: 311 effective length of database: 6,709,326 effective search space: 2086600386 effective search space used: 2086600386 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (28.0 bits)