BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P0A9S3 (346 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4UEJ-A nrPDB 714 0.0 4EJ6-A nrPDB 152 2e-37 5VM2-A nrPDB 144 4e-35 4ILK-A nrPDB 140 9e-34 2DQ4-A nrPDB 139 2e-33 3GFB-A nrPDB 132 3e-31 2DFV-A nrPDB 130 7e-31 3QE3-A nrPDB 122 2e-28 4OH1-A nrPDB 120 6e-28 1E3J-A nrPDB 119 2e-27 1PL8-A nrPDB 118 5e-27 6DKH-A nrPDB 116 2e-26 4CPD-A nrPDB 114 9e-26 5KIA-A nrPDB 114 9e-26 1H2B-A nrPDB 107 1e-23 3IP1-A nrPDB 103 1e-22 3M6I-A nrPDB 95 5e-20 1LLU-A nrPDB 93 2e-19 3S2F-A nrPDB 92 3e-19 3MEQ-A nrPDB 92 4e-19 1F8F-A nrPDB 91 6e-19 5TNX-A nrPDB 91 7e-19 1E3E-A nrPDB 91 7e-19 1CDO-A nrPDB 89 2e-18 1HSO-A nrPDB 89 3e-18 3COS-A nrPDB 89 3e-18 6FG0-A nrPDB 87 1e-17 2EER-A nrPDB 87 1e-17 1U3W-A nrPDB 87 1e-17 1HSZ-A nrPDB 87 2e-17 4Z6K-A nrPDB 86 3e-17 4RQU-A nrPDB 85 4e-17 3PII-A nrPDB 84 7e-17 5YLN-A nrPDB 84 1e-16 4DLA-A nrPDB 82 2e-16 3WLE-A nrPDB 80 1e-15 4JJI-A nrPDB 79 3e-15 1EE2-A nrPDB 78 5e-15 1KEV-A nrPDB 76 2e-14 1MC5-A nrPDB 76 2e-14 3FSR-A nrPDB 76 2e-14 1R37-A nrPDB 75 3e-14 6N7L-A nrPDB 75 3e-14 4EEZ-A nrPDB 75 4e-14 3FPL-A nrPDB 75 5e-14 1YKF-A nrPDB 74 7e-14 1D1T-A nrPDB 74 7e-14 3FPC-A nrPDB 74 9e-14 1YQX-A nrPDB 71 5e-13 1P0F-A nrPDB 70 1e-12 2H6E-A nrPDB 67 1e-11 1UUF-A nrPDB 65 4e-11 2OUI-A nrPDB 64 1e-10 5K1S-A nrPDB 63 2e-10 3TWO-A nrPDB 62 3e-10 4GKV-A nrPDB 62 5e-10 5VKT-A nrPDB 59 2e-09 5Z0C-A nrPDB 57 8e-09 5H82-A nrPDB 57 9e-09 4OAQ-A nrPDB 56 2e-08 3UOG-A nrPDB 55 3e-08 5YAT-A nrPDB 55 5e-08 5H83-A nrPDB 53 2e-07 4J6F-A nrPDB 52 4e-07 2VCY-A nrPDB 52 5e-07 5ENV-A nrPDB 51 9e-07 6C49-A nrPDB 50 2e-06 4JLW-A nrPDB 47 1e-05 1YB5-A nrPDB 47 1e-05 1KOL-A nrPDB 47 2e-05 5FI5-A nrPDB 47 2e-05 3TQH-A nrPDB 46 2e-05 3HZZ-A nrPDB 46 3e-05 2DPH-A nrPDB 44 1e-04 1Q1N-A nrPDB 41 6e-04 3QWB-A nrPDB 41 7e-04 2VN8-A nrPDB 39 0.003 4IDE-A nrPDB 39 0.005 3FBG-A nrPDB 38 0.007 4RVS-A nrPDB 38 0.008 4A10-A nrPDB 37 0.010 1QOR-A nrPDB 36 0.022 1WLY-A nrPDB 36 0.030 3B70-A nrPDB 35 0.036 2VHY-A nrPDB 34 0.073 4TXK-A nrPDB 34 0.100 2BRY-A nrPDB 33 0.14 4DZR-A nrPDB 33 0.21 3KD3-A nrPDB 32 0.34 4ADL-A nrPDB 32 0.37 2EEZ-A nrPDB 32 0.57 1SN7-A nrPDB 31 0.66 1NHQ-A nrPDB 31 0.78 2CF5-A nrPDB 31 0.79 1YFM-A nrPDB 31 0.98 3VH2-A nrPDB 31 0.99 1T1I-A nrPDB 30 1.1 3T7E-A nrPDB 30 1.3 3SLK-A nrPDB 30 1.5 1XLT-A nrPDB 30 1.6 1T1E-A nrPDB 30 2.1 2YFH-A nrPDB 29 2.5 3QBP-A nrPDB 29 3.3 4FHN-X nrPDB 29 3.5 1X14-A nrPDB 29 3.8 3TV2-A nrPDB 28 4.8 4EYE-A nrPDB 28 5.2 4HGV-A nrPDB 28 8.5 2Z7X-A nrPDB 27 9.8 >4UEJ-A nrPDB Length = 346 Score = 714 bits (1843), Expect = 0.0, Method: Compositional matrix adjust. Identities = 346/346 (100%), Positives = 346/346 (100%) Query: 1 MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHE 60 MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHE Sbjct: 1 MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHE 60 Query: 61 FSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEY 120 FSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEY Sbjct: 61 FSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEY 120 Query: 121 IVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCA 180 IVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCA Sbjct: 121 IVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCA 180 Query: 181 VALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVP 240 VALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVP Sbjct: 181 VALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVP 240 Query: 241 QTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWE 300 QTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWE Sbjct: 241 QTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWE 300 Query: 301 TASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP 346 TASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP Sbjct: 301 TASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP 346 >4EJ6-A nrPDB Length = 370 Score = 152 bits (384), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 111/350 (31%), Positives = 174/350 (49%), Gaps = 15/350 (4%) Query: 1 MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHE 60 MK+V ++ G + V IPE D++ VK+ + G+CG+D + P+TLGHE Sbjct: 24 MKAVRLESVGNISVRNVGIPE-PGPDDLLVKVEACGICGTDRHLLHGEFPSTPPVTLGHE 82 Query: 61 FSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEY 120 F G + GS V D+ PG + P + C CP+C G + C IG RDGGFAEY Sbjct: 83 FCGIVVEAGSAVRDIAPGARITGDPNISCGRCPQCQAGRVNLCRNLRAIGIHRDGGFAEY 142 Query: 121 IVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCA 180 ++V RK F +P + GAF EP+ LH L+ V I+G G IGLL +Q A Sbjct: 143 VLVPRKQAFEIPLTLDPVHGAFCEPLACCLHGVDLSGIKAGSTVAILGGGVIGLLTVQLA 202 Query: 181 VALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRF----NQLILET 236 GA +V + K LA+ GA T + S + ++++ + +++E Sbjct: 203 RLAGATTVILSTRQATKRRLAEEVGATATVDPS--AGDVVEAIAGPVGLVPGGVDVVIEC 260 Query: 237 AGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPG 296 AGV +TV+ + +A + ++G L Q + F IL +EL V+GS++N P+ Sbjct: 261 AGVAETVKQSTRLAKAGGTVVILGVLPQGEKVEIEPF-DILFRELRVLGSFIN---PF-- 314 Query: 297 QEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP 346 A+ L+ + ++ +I+ R S + + + A A KVL+IP Sbjct: 315 -VHRRAADLVATGAIEIDRMISRRISLDEAPDVISNPA-AAGEVKVLVIP 362 >5VM2-A nrPDB Length = 347 Score = 144 bits (364), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 97/335 (28%), Positives = 161/335 (48%), Gaps = 20/335 (5%) Query: 10 GIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYP------ITLGHEFSG 63 G +++ + IP + +DEV +K+ G+CGSD+ F++G P I LGHE +G Sbjct: 12 GTMKIISAEIP-VPKEDEVLIKVEYVGICGSDV-HGFESGPFIPPKDPNQEIGLGHECAG 69 Query: 64 YIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRD--GGFAEYI 121 + AVGS V PGD V P +PC C CL+G Y+ C DF+ ++ + G Y+ Sbjct: 70 TVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYRGALTHYL 129 Query: 122 VVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAV 181 + LP +M +G +EP VG+HA LA K +II+GAG IGL+ +Q Sbjct: 130 CHPESFTYKLPDNMDTMEGTLVEPAAVGMHAAMLADVKPGKKIIILGAGCIGLMTLQACK 189 Query: 182 ALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQ 241 LGA + +D+ ++LA+A+ GA N ++ E ++ ETAG Sbjct: 190 CLGATEIAVVDVLEKRLAMAEQLGATVVINGAKEDTIARCQQFTEDMGADIVFETAGSAV 249 Query: 242 TVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWET 301 TV+ A + ++ +VGT+ ++ F KI R+ I + Y++ +P Sbjct: 250 TVKQAPYLVMRGGKIMIVGTVP---GASAINFLKINRE--VTIQTVFRYANRYP-----V 299 Query: 302 ASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARN 336 ++ + ++ ++ H + QA + N Sbjct: 300 TIEAISSGRFDVKSMVTHIYDYRDVQQAFEESVNN 334 >4ILK-A nrPDB Length = 359 Score = 140 bits (352), Expect = 9e-34, Method: Compositional matrix adjust. Identities = 106/333 (31%), Positives = 160/333 (48%), Gaps = 16/333 (4%) Query: 1 MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFK--NGAHYYPITLG 58 MKS++ + + + E IP EVRVK+ +G+CGSD I++ N YP +G Sbjct: 21 MKSILIEKPNQLSIIEREIP-TPSAGEVRVKVKLAGICGSD-SHIYRGHNPFAKYPRVIG 78 Query: 59 HEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFA 118 HEF G IDAVG GV+ G+ VA P++ C C C G + C +G DGGF+ Sbjct: 79 HEFFGVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNVCTTLAVLGVHADGGFS 138 Query: 119 EYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQ 178 EY VV KN + +P + + IEP T+ + Q EN V++ GAG IGL +Q Sbjct: 139 EYAVVPAKNAWKIPEAVADQYAVMIEPFTIAANVTGHGQPTENDTVLVYGAGPIGLTIVQ 198 Query: 179 CAVAL-GAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETA 237 + K+V D E+L AK GA N+S+ P +S + LI++ A Sbjct: 199 VLKGVYNVKNVIVADRIDERLEKAKESGADWAINNSQ--TPLGESFAEKGIKPTLIIDAA 256 Query: 238 GVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQ 297 P ++ AV +A P A++ L+G + + I KEL++ S +N Sbjct: 257 CHPSILKEAVTLASPAARIVLMGFSSEPSEVIQQG---ITGKELSIFSSRLN------AN 307 Query: 298 EWETASRLLTERKLSLEPLIAHRGSFESFAQAV 330 ++ L++ + E LI H F+ A A+ Sbjct: 308 KFPVVIDWLSKGLIKPEKLITHTFDFQHVADAI 340 >2DQ4-A nrPDB Length = 343 Score = 139 bits (349), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 93/310 (30%), Positives = 150/310 (48%), Gaps = 18/310 (5%) Query: 27 EVRVKIASSGLCGSDLPRIFK-----NGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAV 81 E+ V++ ++ +CG+DL I+K G P+ GHEFSG ++AVG GV GD V Sbjct: 27 EILVRVEAASICGTDL-HIWKWDAWARGRIRPPLVTGHEFSGVVEAVGPGVRRPQVGDHV 85 Query: 82 ACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGA 141 + + C CP C G Y C +G RDGGFAEY+VV +N + P D+P E A Sbjct: 86 SLESHIVCHACPACRTGNYHVCLNTQILGVDRDGGFAEYVVVPAENAWVNPKDLPFEVAA 145 Query: 142 FIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALA 201 +EP +H + G K+V+I GAG IGL+A A GA + D + +LA A Sbjct: 146 ILEPFGNAVHTVYAGSGVSGKSVLITGAGPIGLMAAMVVRASGAGPILVSDPNPYRLAFA 205 Query: 202 KSFGAMQTFNSSEMSAPQMQSVLRELRFN--QLILETAGVPQTVELAVEIAGPHAQLALV 259 + + A + N E + V+R + + +++LE +G + + P + ++ Sbjct: 206 RPY-ADRLVNPLEE---DLLEVVRRVTGSGVEVLLEFSGNEAAIHQGLMALIPGGEARIL 261 Query: 260 GTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAH 319 G + A G+++ + +T G + W Q W + L+ ++ L PL+ H Sbjct: 262 GIPSDPIRFDLA--GELVMRGITAFG--IAGRRLW--QTWMQGTALVYSGRVDLSPLLTH 315 Query: 320 RGSFESFAQA 329 R + +A Sbjct: 316 RLPLSRYREA 325 >3GFB-A nrPDB Length = 350 Score = 132 bits (331), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 99/333 (29%), Positives = 153/333 (45%), Gaps = 29/333 (8%) Query: 27 EVRVKIASSGLCGSDLPRIFKNGAHYY------------PITLGHEFSGYIDAVGSGVDD 74 EV +K+ ++ +CG+DL H Y P +GHE +G + VG GV+D Sbjct: 31 EVLIKVLATSICGTDL--------HIYEWNEWAQSRIKPPQIMGHEVAGEVVEVGPGVED 82 Query: 75 LHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTD 134 L GD ++ + C C C Y C G DG FA Y +V KN + P D Sbjct: 83 LQVGDYISVETHIVCGKCYACKHNRYHVCQNTKIFGVDMDGVFAHYAIVPAKNAWKNPKD 142 Query: 135 MPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDIS 194 MP E A EP+ + LA ++ +I GAG +GLL I A A GA V + S Sbjct: 143 MPPEYAALQEPLGNAVDTV-LAGPIAGRSTLITGAGPLGLLGIAVAKASGAYPVIVSEPS 201 Query: 195 SEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHA 254 + LAK GA N E + + + ++ LE +G P+ +E ++ P Sbjct: 202 EFRRKLAKKVGADYVVNPFEEDPVKFVMDITDGAGVEVFLEFSGAPKALEQGLKAVTPGG 261 Query: 255 QLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLE 314 +++L+G +++ + I+ K L V G + W + W T S L+ KL+L+ Sbjct: 262 RVSLLGLFPREVTIDFNNL--IIFKALEVHG--ITGRHLW--ETWYTVSSLIQSGKLNLD 315 Query: 315 PLIAHR-GSFESFAQAVRDIARNAMPGKVLLIP 346 P+I H+ F+ F +A ++ R GKV+ P Sbjct: 316 PIITHKYKGFDKFEEAF-ELMRAGKTGKVVFFP 347 >2DFV-A nrPDB Length = 347 Score = 130 bits (328), Expect = 7e-31, Method: Compositional matrix adjust. Identities = 98/332 (29%), Positives = 154/332 (46%), Gaps = 29/332 (8%) Query: 27 EVRVKIASSGLCGSDLPRIFKNGAHYY------------PITLGHEFSGYIDAVGSGVDD 74 EV +K+ ++ +CG+DL H Y P +GHE +G + +G GV+ Sbjct: 30 EVLIKVLATSICGTDL--------HIYEWNEWAQSRIKPPQIMGHEVAGEVVEIGPGVEG 81 Query: 75 LHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTD 134 + GD V+ + C C C +G Y C G DG FAEY VV +N++ P Sbjct: 82 IEVGDYVSVETHIVCGKCYACRRGQYHVCQNTKIFGVDTDGVFAEYAVVPAQNIWKNPKS 141 Query: 135 MPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDIS 194 +P E EP+ + LA K+V+I GAG +GLL I A A GA V + S Sbjct: 142 IPPEYATLQEPLGNAVDTV-LAGPISGKSVLITGAGPLGLLGIAVAKASGAYPVIVSEPS 200 Query: 195 SEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHA 254 + LAK GA N E + + + + LE +G P+ +E ++ P Sbjct: 201 DFRRELAKKVGADYVINPFEEDVVKEVMDITDGNGVDVFLEFSGAPKALEQGLQAVTPAG 260 Query: 255 QLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLE 314 +++L+G + + I+ K LT+ G + W + W T SRLL KL+L+ Sbjct: 261 RVSLLGLYPGKVTIDFNNL--IIFKALTIYG--ITGRHLW--ETWYTVSRLLQSGKLNLD 314 Query: 315 PLIAHR-GSFESFAQAVRDIARNAMPGKVLLI 345 P+I H+ F+ + +A ++ R GKV+ + Sbjct: 315 PIITHKYKGFDKYEEAF-ELMRAGKTGKVVFM 345 >3QE3-A nrPDB Length = 355 Score = 122 bits (307), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 101/342 (29%), Positives = 157/342 (45%), Gaps = 33/342 (9%) Query: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYY--------- 53 S+V G +R+ IPE +EV +K+ S G+CGSD+ HY+ Sbjct: 9 SLVVHGPGDLRLENYPIPE-PGPNEVLLKMHSVGICGSDV--------HYWQHGRIGDFV 59 Query: 54 ---PITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIG 110 P+ LGHE SG + VGS V L PGD VA P P T C G Y+ F Sbjct: 60 VKKPMVLGHEASGTVVKVGSLVRHLQPGDRVAIQPGAPRQTDEFCKIGRYNLSPTIFFCA 119 Query: 111 SR-RDGGFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGA 169 + DG + + LP ++ E+GA IEP++VG+HA A V++ GA Sbjct: 120 TPPDDGNLCRFYKHNANFCYKLPDNVTFEEGALIEPLSVGIHACRRAGVTLGNKVLVCGA 179 Query: 170 GTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRF 229 G IGL+ + A A+GA V D+S+ +L+ AK GA S S ++ + L Sbjct: 180 GPIGLVNLLAAKAMGAAQVVVTDLSASRLSKAKEVGADFILEISNESPEEIAKKVEGLLG 239 Query: 230 N--QLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSW 287 + ++ +E GV +++ + L LVG + +TS +E+ + G + Sbjct: 240 SKPEVTIECTGVETSIQAGIYATHSGGTLVLVGLGSE---MTSVPLVHAATREVDIKGVF 296 Query: 288 MNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQA 329 Y + WP A +L + ++++PL+ HR E +A Sbjct: 297 -RYCNTWP-----MAISMLASKSVNVKPLVTHRFPLEKALEA 332 >4OH1-A nrPDB Length = 351 Score = 120 bits (302), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 80/253 (31%), Positives = 125/253 (49%), Gaps = 15/253 (5%) Query: 6 NDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSD-------LPRIFKNGAHYYPITLG 58 +T G V + E+ +PE K + E+R+K+ + +CGSD L + P++ G Sbjct: 15 KNTMGTVDMMEAPMPEPKDE-EIRIKVVYASICGSDTHILTGNLGEMESTTRSMLPMSFG 73 Query: 59 HEFSGYIDAVGSGVDDL--HPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGG 116 HE SG ID VGS + + G V C C C +G + C+ + R G Sbjct: 74 HELSGVIDKVGSTAEKMGFKVGQKVVANYAKYCGCCENCREGKVNLCSNMGY----RMNG 129 Query: 117 FAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLA 176 F+EY V +F +P D ++D A +EP+TV L + A+ K+V I+GAG +G++ Sbjct: 130 FSEYAVYHMSQIFPIPDDADLKDYALVEPLTVALSSAEQAKISYGKSVAIMGAGGLGMML 189 Query: 177 IQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILET 236 +Q A GA ++T DI EKL LA GA NS+E + L R++ +LE Sbjct: 190 VQLARLAGASTITVFDIVPEKLELALENGADYALNSAEEGVAERAIELAGGRYD-CVLEG 248 Query: 237 AGVPQTVELAVEI 249 G +L +++ Sbjct: 249 TGATAAAKLGLQL 261 >1E3J-A nrPDB Length = 352 Score = 119 bits (298), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 96/336 (28%), Positives = 155/336 (46%), Gaps = 38/336 (11%) Query: 12 VRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYY------------PITLGH 59 +R+ + IPE K +DEV +++A G+CGSD+ HYY P+ +GH Sbjct: 16 LRLEQRPIPEPK-EDEVLLQMAYVGICGSDV--------HYYEHGRIADFIVKDPMVIGH 66 Query: 60 EFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSR-RDGGFA 118 E SG + VG V L GD VA P +PC C C +G Y+ C F + DG A Sbjct: 67 EASGTVVKVGKNVKHLKKGDRVAVEPGVPCRRCQFCKEGKYNLCPDLTFCATPPDDGNLA 126 Query: 119 EYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQ 178 Y V LP ++ +E+GA +EP++VG+HA A V++IGAG IGL+++ Sbjct: 127 RYYVHAADFCHKLPDNVSLEEGALLEPLSVGVHACRRAGVQLGTTVLVIGAGPIGLVSVL 186 Query: 179 CAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELR-----FNQLI 233 A A GA V S +L +AK+ GA T + + + S++ +R + Sbjct: 187 AAKAYGA-FVVCTARSPRRLEVAKNCGADVTL-VVDPAKEEESSIIERIRSAIGDLPNVT 244 Query: 234 LETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSP 293 ++ +G + + + + I L LVG Q + + +E+ I S Y + Sbjct: 245 IDCSGNEKCITIGINITRTGGTLMLVGMGSQ---MVTVPLVNACAREID-IKSVFRYCND 300 Query: 294 WPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQA 329 +P A ++ + +++ L+ H E A Sbjct: 301 YP-----IALEMVASGRCNVKQLVTHSFKLEQTVDA 331 >1PL8-A nrPDB Length = 356 Score = 118 bits (295), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 96/351 (27%), Positives = 157/351 (44%), Gaps = 39/351 (11%) Query: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYY--------- 53 S+V G +R+ IPE +EV +++ S G+CGSD+ HY+ Sbjct: 10 SLVVHGPGDLRLENYPIPE-PGPNEVLLRMHSVGICGSDV--------HYWEYGRIGNFI 60 Query: 54 ---PITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIG 110 P+ LGHE SG ++ VGS V L PGD VA P P C G Y+ F Sbjct: 61 VKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCA 120 Query: 111 SR-RDGGFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGA 169 + DG + + LP ++ E+GA IEP++VG+HA V++ GA Sbjct: 121 TPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGA 180 Query: 170 GTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRF 229 G IG++ + A A+GA V D+S+ +L+ AK GA S+ S Q + R++ Sbjct: 181 GPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESP---QEIARKVEG 237 Query: 230 N-----QLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVI 284 ++ +E G +++ + L LVG + +T+ +E+ + Sbjct: 238 QLGCKPEVTIECTGAEASIQAGIYATRSGGTLVLVGLGSE---MTTVPLLHAAIREVDIK 294 Query: 285 GSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIAR 335 G + Y + WP A +L + ++++PL+ HR E +A + Sbjct: 295 GVF-RYCNTWP-----VAISMLASKSVNVKPLVTHRFPLEKALEAFETFKK 339 >6DKH-A nrPDB Length = 346 Score = 116 bits (290), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 96/336 (28%), Positives = 140/336 (41%), Gaps = 45/336 (13%) Query: 30 VKIASSGLCGSDLPRIFKNGAHYY------------PITLGHEFSGYIDAVGSGVDDLHP 77 V+I G+CGSDL HYY P+ LGHE G + + S +LH Sbjct: 35 VQITRGGICGSDL--------HYYQEGKVGNFMIKAPMVLGHEVIGKV--IHSDSSELHE 84 Query: 78 GDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGS-----RRDGGFAEYIVVKRKNVFALP 132 G VA P PC C C++ +QC F GS DGGF Y +V+ P Sbjct: 85 GQTVAINPSKPCGHCKYCIEHNENQCTDMRFFGSAMYFPHVDGGFTRYKMVETSQCVPYP 144 Query: 133 TDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAID 192 + AF EP+ V +HA H A + K V I G G IG L + LGA + D Sbjct: 145 AKADEKVMAFAEPLAVAIHAAHQAGELQGKRVFISGVGPIGCLIVSAVKTLGAAEIVCAD 204 Query: 193 ISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIA-- 250 +S L+L K GA N M E + + E +G P +V +E+ Sbjct: 205 VSPRSLSLGKEMGADVLVNPQN---DDMDHWKAEKGYFDVSFEVSGHPSSVNTCLEVTRA 261 Query: 251 -GPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTER 309 G Q+ + G + + +T ++ KE+++ GS+ S E+ TA L Sbjct: 262 RGVMVQVGMGGAMAEFPMMT------LIGKEISLRGSFRFTS------EFNTAVSWLANG 309 Query: 310 KLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLI 345 ++ PL++ F +A+R KV L+ Sbjct: 310 VINPLPLLSAEYPFTDLEEALRFAGDKTQAAKVQLV 345 >4CPD-A nrPDB Length = 347 Score = 114 bits (284), Expect = 9e-26, Method: Compositional matrix adjust. Identities = 87/270 (32%), Positives = 131/270 (48%), Gaps = 11/270 (4%) Query: 1 MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPIT-LGH 59 M++VV + V V E P ++H + V++ +G+CGSDL ++ P + LGH Sbjct: 1 MRAVVFENKERVAVKEVNAPRLQHPLDALVRVHLAGICGSDL-HLYHGKIPVLPGSVLGH 59 Query: 60 EFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAK-----YDFIGSRRD 114 EF G ++AVG G+ DL PGD V + C TCP C + Y+ C + Y + Sbjct: 60 EFVGQVEAVGEGIQDLQPGDWVVGPFHIACGTCPYCRRHQYNLCERGGVYGYGPMFGNLQ 119 Query: 115 GGFAEYIVVKRKNV--FALPTDMPIEDGAFIEPI-TVGLHAFHLAQGCENKNVIIIGAGT 171 G AE + V NV LP ++ E F I + Q +V +IGAG Sbjct: 120 GAQAEILRVPFSNVNLRKLPPNLSPERAIFAGDILSTAYGGLIQGQLRPGDSVAVIGAGP 179 Query: 172 IGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQ 231 +GL+AI+ A LGA + AID E+L A S GA+ E +++S + Sbjct: 180 VGLMAIEVAQVLGASKILAIDRIPERLERAASLGAIPINAEQENPVRRVRSETND-EGPD 238 Query: 232 LILETAGVPQTVELAVEIAGPHAQLALVGT 261 L+LE G T+ LA+E+ P +++ VG Sbjct: 239 LVLEAVGGAATLSLALEMVRPGGRVSAVGV 268 >5KIA-A nrPDB Length = 351 Score = 114 bits (284), Expect = 9e-26, Method: Compositional matrix adjust. Identities = 93/333 (27%), Positives = 159/333 (47%), Gaps = 23/333 (6%) Query: 20 PEIKHQDEVRVKIASSGLCGSDLPRIFK--NGAHY---YPITLGHEFSGYIDAVGSGVDD 74 PE+ H D V +KI + +CG+D+ I+K + A P+ +GHE+ G I +G V Sbjct: 29 PEVGHND-VLIKIRRTAICGTDI-HIWKWDDWAQKTIPVPMHVGHEYVGEIVEMGQEVRG 86 Query: 75 LHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTD 134 GD V+ + C C C G C +G R+G FAEY+ + N F +P + Sbjct: 87 FSIGDRVSGEGHITCGFCRNCRAGRRHLCRNTVGVGVNREGAFAEYLAIPAFNAFKIPPE 146 Query: 135 MPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDIS 194 + + A +P H L+ ++V+I GAG IG++A+ A +GA++V DI+ Sbjct: 147 ISDDLAAIFDPFGNATHT-ALSFNLVGEDVLITGAGPIGVMAVAIAKHVGARNVVITDIN 205 Query: 195 SEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHA 254 +L LA+ GA + N S S + + L + LE +GVP +E Sbjct: 206 DYRLDLARRMGATRAVNVSRESLRDVMADLHMTEGFDVGLEMSGVPSAFTSLLESMNHGG 265 Query: 255 QLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQE-WETASRL--LTERKL 311 ++AL+G T+ + +++ K L + G + G+E +ET ++ + + L Sbjct: 266 KVALLGIPPAQ---TAIDWNQVIFKGLEIKGIY--------GREMFETWYKMVAMLQSGL 314 Query: 312 SLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 L P+I HR + + + + + + GKV+L Sbjct: 315 DLSPIITHRFAVDDYEKGFAAML-SGESGKVIL 346 >1H2B-A nrPDB Length = 359 Score = 107 bits (266), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 76/260 (29%), Positives = 123/260 (47%), Gaps = 13/260 (5%) Query: 12 VRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAH-----YYPITLGHEFSGYID 66 +R+ + P ++ + +V V+IA +G+C +DL + + H P TLGHE GYI+ Sbjct: 28 LRIEDVDYPRLEGRFDVIVRIAGAGVCHTDL-HLVQGMWHELLQPKLPYTLGHENVGYIE 86 Query: 67 AVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRK 126 V GV+ L GD V P + TC C G C +F G DGGFAE++ + Sbjct: 87 EVAEGVEGLEKGDPVILHPAVTDGTCLACRAGEDMHCENLEFPGLNIDGGFAEFMRTSHR 146 Query: 127 NVFALPTDMPIEDGAFIEPIT-VGLHAFHLAQGCENK-----NVIIIGAGTIGLLAIQCA 180 +V LP D+ E + P+ G+ A+ + V I+G G +G +A+Q Sbjct: 147 SVIKLPKDISREKLVEMAPLADAGITAYRAVKKAARTLYPGAYVAIVGVGGLGHIAVQLL 206 Query: 181 VALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVP 240 + +V A+D+ EKL LA+ GA ++ Q+ + R N + ++ G Sbjct: 207 KVMTPATVIALDVKEEKLKLAERLGADHVVDARRDPVKQVMELTRGRGVN-VAMDFVGSQ 265 Query: 241 QTVELAVEIAGPHAQLALVG 260 TV+ + G +L +VG Sbjct: 266 ATVDYTPYLLGRMGRLIIVG 285 >3IP1-A nrPDB Length = 404 Score = 103 bits (257), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 85/290 (29%), Positives = 126/290 (43%), Gaps = 28/290 (9%) Query: 12 VRVAESVIPEIKHQDEVRVKIASSGLCGSDL--------PRIFKNGAHYYPITLGHEFSG 63 VRV E P I+ E+ +K+ + G+CGSD+ I G +P+TLGHEFSG Sbjct: 42 VRVEEVPEPRIEKPTEIIIKVKACGICGSDVHMAQTDEEGYILYPGLTGFPVTLGHEFSG 101 Query: 64 YIDAVGSGVDD------LHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGF 117 + G + G+ V +L C C C +GF + C + +G DG F Sbjct: 102 VVVEAGPEAINRRTNKRFEIGEPVCAEEMLWCGHCRPCAEGFPNHCENLNELGFNVDGAF 161 Query: 118 AEYIVVKRKNVFALPT-------DMPIEDGAFIEPITVGLHAFHLAQGC--ENKNVIIIG 168 AEY+ V K ++L D G+ +EP +V +A + G NV+I+G Sbjct: 162 AEYVKVDAKYAWSLRELEGVYEGDRLFLAGSLVEPTSVAYNAVIVRGGGIRPGDNVVILG 221 Query: 169 AGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELR 228 G IGL A+ GA V + S + LAK GA + ++ + + Sbjct: 222 GGPIGLAAVAILKHAGASKVILSEPSEVRRNLAKELGADHVIDPTKENFVEAVLDYTNGL 281 Query: 229 FNQLILETAGVPQTV-----ELAVEIAGPHAQLALVGTLHQDLHLTSATF 273 +L LE GVPQ V E+ G +A +A+V + LT F Sbjct: 282 GAKLFLEATGVPQLVWPQIEEVIWRARGINATVAIVARADAKIPLTGEVF 331 >3M6I-A nrPDB Length = 363 Score = 94.7 bits (234), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 88/315 (27%), Positives = 138/315 (43%), Gaps = 21/315 (6%) Query: 25 QDEVRVKIASSGLCGSDLPRIFKNGAHYYPIT-----LGHEFSGYIDAVGSGVDDLHPGD 79 + EV V + S+G+CGSD+ +K+G I LGHE +G + AV V + GD Sbjct: 40 EGEVTVAVRSTGICGSDV-HFWKHGCIGPMIVECDHVLGHESAGEVIAVHPSVKSIKVGD 98 Query: 80 AVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIED 139 VA P + C C CL G Y+ C + DF+ + G V +M E+ Sbjct: 99 RVAIEPQVICNACEPCLTGRYNGCERVDFLSTPPVPGLLRRYVNHPAVWCHKIGNMSYEN 158 Query: 140 GAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLA 199 GA +EP++V L A V+I GAG IGL+ + CA A GA + DI +L Sbjct: 159 GAMLEPLSVALAGLQRAGVRLGDPVLICGAGPIGLITMLCAKAAGACPLVITDIDEGRLK 218 Query: 200 LAKSFG-AMQTFNSSEMSAPQMQSVLRELRFN----QLILETAGVPQTVELAVEIAGPHA 254 AK + T +SA + + E F + LE GV ++ A+ Sbjct: 219 FAKEICPEVVTHKVERLSAEESAKKIVE-SFGGIEPAVALECTGVESSIAAAIWAVKFGG 277 Query: 255 QLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLE 314 ++ ++G ++ + F + +E+ + + Y + WP A RL+ + L Sbjct: 278 KVFVIGVGKNEIQI---PFMRASVREVDLQFQY-RYCNTWP-----RAIRLVENGLVDLT 328 Query: 315 PLIAHRGSFESFAQA 329 L+ HR E +A Sbjct: 329 RLVTHRFPLEDALKA 343 >1LLU-A nrPDB Length = 342 Score = 92.8 bits (229), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 85/268 (31%), Positives = 128/268 (47%), Gaps = 20/268 (7%) Query: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITL--GHE 60 +VV+ +R+ E +P + +V VKI +SG+C +DL + P+ GHE Sbjct: 10 AVVHAYGAPLRIEEVKVP-LPGPGQVLVKIEASGVCHTDLHAAEGDWPVKPPLPFIPGHE 68 Query: 61 FSGYIDAVGSGVDDLHPGDAVACVPLL--PCFTCPECLKGFYSQCAKYDFIGSRRDGGFA 118 GY+ AVGSGV + GD V +P L C C CL G+ + C G +GG+A Sbjct: 69 GVGYVAAVGSGVTRVKEGDRVG-IPWLYTACGCCEHCLTGWETLCESQQNTGYSVNGGYA 127 Query: 119 EYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKN------VIIIGAGTI 172 EY++ V LP ++ A I PI + +G + N V I G G + Sbjct: 128 EYVLADPNYVGILPKNVEF---AEIAPILCA--GVTVYKGLKQTNARPGQWVAISGIGGL 182 Query: 173 GLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQL 232 G +A+Q A A+G V AIDI KL LA+ GA T N+ + ++++ R++ Sbjct: 183 GHVAVQYARAMGLH-VAAIDIDDAKLELARKLGASLTVNARQEDP--VEAIQRDIGGAHG 239 Query: 233 ILETAGVPQTVELAVEIAGPHAQLALVG 260 +L TA A+ +A +ALVG Sbjct: 240 VLVTAVSNSAFGQAIGMARRGGTIALVG 267 >3S2F-A nrPDB Length = 340 Score = 92.4 bits (228), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 86/281 (30%), Positives = 130/281 (46%), Gaps = 32/281 (11%) Query: 27 EVRVKIASSGLCGSDLPRIFKNG--AHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACV 84 +V+VKI +SG+C +DL + P GHE GY+ AVGSGV + GD V V Sbjct: 29 QVQVKIEASGVCHTDLHAADGDWPVKPTLPFIPGHEGVGYVSAVGSGVSRVKEGDRVG-V 87 Query: 85 PLL--PCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAF 142 P L C C CL+G+ + C K G +GG+ EY+V V LP + F Sbjct: 88 PWLYSACGYCEHCLQGWETLCEKQQNTGYSVNGGYGEYVVADPNYVGLLPDKV-----GF 142 Query: 143 IEPITVGLHAFHLAQGCE------NKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSE 196 +E + + +G + + V+I G G +G +A+Q A A+G + V A+DI Sbjct: 143 VEIAPILCAGVTVYKGLKVTDTRPGQWVVISGIGGLGHVAVQYARAMGLR-VAAVDIDDA 201 Query: 197 KLALAKSFGAMQTFNSSEMS-APQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQ 255 KL LA+ GA N+ + A +Q +E+ +L TA P+ A+ + Sbjct: 202 KLNLARRLGAEVAVNARDTDPAAWLQ---KEIGGAHGVLVTAVSPKAFSQAIGMVRRGGT 258 Query: 256 LALVGTLHQDLHLTSATFG----KILRKELTVIGSWMNYSS 292 +AL G L FG ++ K +T+ GS + S Sbjct: 259 IALNG-------LPPGDFGTPIFDVVLKGITIRGSIVGTRS 292 >3MEQ-A nrPDB Length = 365 Score = 91.7 bits (226), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 84/268 (31%), Positives = 128/268 (47%), Gaps = 16/268 (5%) Query: 27 EVRVKIASSGLCGSDLPRIFKNG--AHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACV 84 +++V I +SG+C +DL + P GHE G++ AVGSGV + GD V + Sbjct: 52 QIQVAIQASGVCHTDLHAAEGDWPVKPNPPFIPGHEGVGFVSAVGSGVKHVKEGDRVG-I 110 Query: 85 PLL--PCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAF 142 P L C C CL G+ + C + G +GGFAEY+V V LP ++ + Sbjct: 111 PWLYTACGHCRHCLGGWETLCEEQLNTGYSVNGGFAEYVVADPNFVGHLPKNIDFNE--- 167 Query: 143 IEPI-TVGLHAFHLAQGCENKN---VIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKL 198 I P+ G+ + + + K V+I G G +G +A+Q A A+G +V A+DI KL Sbjct: 168 IAPVLCAGVTVYKGLKVTDTKPGDWVVISGIGGLGHMAVQYARAMGL-NVAAVDIDDRKL 226 Query: 199 ALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLAL 258 LA+ GA T N+ ++ P Q +L TA P+ E A+ + ++L Sbjct: 227 DLARRLGATVTVNAKTVADPAAYIRKETDGGAQGVLVTAVSPKAFEQALGMVARGGTVSL 286 Query: 259 VGTLHQDLHLTSATFGKILRKELTVIGS 286 G D L+ F +L +TV GS Sbjct: 287 NGLPPGDFPLS--IFNMVLNG-VTVRGS 311 >1F8F-A nrPDB Length = 371 Score = 91.3 bits (225), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 92/341 (26%), Positives = 147/341 (43%), Gaps = 49/341 (14%) Query: 26 DEVRVKIASSGLCGSDLPRIFKNGAHYYPI--TLGHEFSGYIDAVGSGVDDLHPGDAVAC 83 DEV VK+ ++G+C +DL I ++ + P+ LGHE SG I+A+G V +L GD V Sbjct: 32 DEVLVKVVATGMCHTDL--IVRDQKYPVPLPAVLGHEGSGIIEAIGPNVTELQVGDHVV- 88 Query: 84 VPLLPCFTCPECLKGFYSQCAKY---DFIGSRRDGG--------------------FAEY 120 + C C +C G + C+++ +F G+ +G FA Y Sbjct: 89 LSYGYCGKCTQCNTGNPAYCSEFFGRNFSGADSEGNHALCTHDQGVVNDHFFAQSSFATY 148 Query: 121 IVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCEN-------KNVIIIGAGTIG 173 + + N + D+PIE + P+ G+ A C N + + GAG +G Sbjct: 149 ALSRENNTVKVTKDVPIE---LLGPLGCGIQTG--AGACINALKVTPASSFVTWGAGAVG 203 Query: 174 LLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLI 233 L A+ A GA + A+DI +L LAK GA NS + + N Sbjct: 204 LSALLAAKVCGASIIIAVDIVESRLELAKQLGATHVINSKTQDPVAAIKEITDGGVN-FA 262 Query: 234 LETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATF--GKILRKELTVIGSWMNYS 291 LE+ G P+ ++ V+ G ++A+VG T+A F +L T++G Sbjct: 263 LESTGSPEILKQGVDALGILGKIAVVGAPQLG---TTAQFDVNDLLLGGKTILGVVEGSG 319 Query: 292 SPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRD 332 SP + RL + K + L+ +F+ QA D Sbjct: 320 SPK--KFIPELVRLYQQGKFPFDQLVKFY-AFDEINQAAID 357 >5TNX-A nrPDB Length = 383 Score = 90.9 bits (224), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 74/272 (27%), Positives = 121/272 (44%), Gaps = 51/272 (18%) Query: 26 DEVRVKIASSGLCGSDLPRIFKNGAHYYPI----TLGHEFSGYIDAVGSGVDDLHPGDAV 81 DEV V++ ++GLC +DL I ++ YYP+ LGHE +G ++AVG V L GD V Sbjct: 43 DEVLVRVVATGLCHTDL--IVRD--QYYPVPLPAVLGHEGAGVVEAVGPNVKTLAAGDHV 98 Query: 82 ACVPLLPCFTCPECLKGFYSQCAKY---DFIGSRRDG--------------------GFA 118 + C C C G + C ++ +F G+ DG FA Sbjct: 99 -VLTYGACGHCASCAGGHGAYCRQFFALNFGGADADGQTALRDAAGEPLHDHFFAQSSFA 157 Query: 119 EYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVII--------IGAG 170 Y + + N +P + P+E + P+ G+ G ++ + GAG Sbjct: 158 SYALARENNAIKVPKEAPLE---LLGPLGCGIQT---GAGAVINSLAVRTGSSFASFGAG 211 Query: 171 TIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFN 230 +G+ A+ A GA ++ A+DI +LALA GA NS E+ + +RE+ Sbjct: 212 AVGMSAVMAARIAGATTIIAVDIVPSRLALALELGATHAINSKEV---DVVDAIREITGG 268 Query: 231 QL--ILETAGVPQTVELAVEIAGPHAQLALVG 260 + LE+ G+P + ++ G + +VG Sbjct: 269 GVDYALESTGLPAVLSQGIDALGSRGTMGVVG 300 >1E3E-A nrPDB Length = 376 Score = 90.9 bits (224), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 93/344 (27%), Positives = 147/344 (42%), Gaps = 57/344 (16%) Query: 27 EVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPL 86 EVR+++ ++ +C +D+ +P+ LGHE +G +++VG GV + PGD V +P Sbjct: 35 EVRIQVIATCVCPTDINATDPKKKALFPVVLGHECAGIVESVGPGVTNFKPGDKV--IPF 92 Query: 87 LP--CFTCPECLKGFYSQCAK----------------------------YDFIGSRRDGG 116 C C CL + C K Y F+G Sbjct: 93 FAPQCKRCKLCLSPLTNLCGKLRNFKYPTIDQELMEDRTSRFTCKGRSIYHFMGVSS--- 149 Query: 117 FAEYIVVKRKNVFALPTDMPIEDGAFIEP-ITVGL-HAFHLAQGCENKNVIIIGAGTIGL 174 F++Y VV N+ + + +E I + G A + A+ + G G +GL Sbjct: 150 FSQYTVVSEANLARVDDEANLERVCLIGCGFSSGYGAAINTAKVTPGSTCAVFGLGCVGL 209 Query: 175 LAI-QCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFN--Q 231 AI C +A GA + AIDI+ EK AK+ GA N E+ P +Q V+ EL Sbjct: 210 SAIIGCKIA-GASRIIAIDINGEKFPKAKALGATDCLNPRELDKP-VQDVITELTAGGVD 267 Query: 232 LILETAGVPQTVELAVE--IAGPHAQLALVGTLHQDLHLTSATFGKILRKEL--TVIGSW 287 L+ AG QT++ AV+ + G +VG + +T T IL + + T G W Sbjct: 268 YSLDCAGTAQTLKAAVDCTVLG-WGSCTVVGAKVDE--MTIPTVDVILGRSINGTFFGGW 324 Query: 288 MNYSS-PWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAV 330 + S P +++ +K L+ L+ H FES A+ Sbjct: 325 KSVDSVPNLVSDYK-------NKKFDLDLLVTHALPFESINDAI 361 >1CDO-A nrPDB Length = 374 Score = 89.4 bits (220), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 64/236 (27%), Positives = 111/236 (47%), Gaps = 32/236 (13%) Query: 14 VAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHY--YPITLGHEFSGYIDAVGSG 71 V E + ++ H +E+R+KI ++G+C +DL +F+ G H +P+ LGHE +G +++VG G Sbjct: 22 VIEEIEVDVPHANEIRIKIIATGVCHTDLYHLFE-GKHKDGFPVVLGHEGAGIVESVGPG 80 Query: 72 VDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAK------------------------YD 107 V + PG+ V + + C C C +QC K Sbjct: 81 VTEFQPGEKVIPLFISQCGECRFCQSPKTNQCVKGWANESPDVMSPKETRFTCKGRKVLQ 140 Query: 108 FIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAFIE-PITVGL-HAFHLAQGCENKNVI 165 F+G+ F++Y VV + V + P++ + ++ G A + A+ Sbjct: 141 FLGTST---FSQYTVVNQIAVAKIDPSAPLDTVCLLGCGVSTGFGAAVNTAKVEPGSTCA 197 Query: 166 IIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQ 221 + G G +GL A+ + GAK + A+D++ +K AK FGA N ++ S P Q Sbjct: 198 VFGLGAVGLAAVMGCHSAGAKRIIAVDLNPDKFEKAKVFGATDFVNPNDHSEPISQ 253 >1HSO-A nrPDB Length = 374 Score = 89.0 bits (219), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 66/224 (29%), Positives = 102/224 (45%), Gaps = 24/224 (10%) Query: 27 EVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPL 86 EVR+K+ + G+CG+D + P+ LGHE +G +++VG GV + PGD V + + Sbjct: 35 EVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAI 94 Query: 87 LPCFTCPECLKGFYSQCAKYDFI---GSRRDG------------------GFAEYIVVKR 125 C C C + C K D G+ +DG F++Y VV Sbjct: 95 PQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDE 154 Query: 126 KNVFALPTDMPIEDGAFIE-PITVGL-HAFHLAQGCENKNVIIIGAGTIGLLAIQCAVAL 183 V + P+E I + G A ++A+ + G G +GL AI A Sbjct: 155 NAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAA 214 Query: 184 GAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLREL 227 GA + A+DI+ +K A AK GA + N + P +Q VL+E+ Sbjct: 215 GAARIIAVDINKDKFAKAKELGATECINPQDYKKP-IQEVLKEM 257 >3COS-A nrPDB Length = 381 Score = 89.0 bits (219), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 92/364 (25%), Positives = 155/364 (42%), Gaps = 65/364 (17%) Query: 27 EVRVKIASSGLCGSDLPRI-FKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVP 85 EVR++I ++ LC +D I K +P+ +GHE +G ++++G GV ++ PGD V +P Sbjct: 37 EVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKV--IP 94 Query: 86 LLP--CFTCPECLKGFYSQCAK----------------------------YDFIGSRRDG 115 L C C CL + C K Y F G+ Sbjct: 95 LYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTST-- 152 Query: 116 GFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKN--------VIII 167 F++Y VV N+ I+D A +E + + F G N + Sbjct: 153 -FSQYTVVSDINL------AKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVF 205 Query: 168 GAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLREL 227 G G +GL A+ A GA + IDI+SEK AK+ GA N ++ P +Q V+ EL Sbjct: 206 GLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKP-IQEVIIEL 264 Query: 228 RFN--QLILETAGVPQTVELAVE-IAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVI 284 L+ AG +T++ A++ +G LT + +EL +I Sbjct: 265 TKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLT------VFPEEL-II 317 Query: 285 GSWMNYSSPWPGQEWETASRLLTE---RKLSLEPLIAHRGSFESFAQAVRDIARNAMPGK 341 G +N + + ++ +L+T+ +K +L+ L+ H F+ ++A D+ + Sbjct: 318 GRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAF-DLMNQGKSIR 376 Query: 342 VLLI 345 +LI Sbjct: 377 TILI 380 >6FG0-A nrPDB Length = 352 Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 89/345 (25%), Positives = 145/345 (42%), Gaps = 51/345 (14%) Query: 27 EVRVKIASSGLCGSDLPRIFKNGAHY---YPITLGHEFSGYIDAVGSGVDDLHPGDAVAC 83 E+ +K+ ++GLC SD+ + A Y P+TLGHE G + +G GV GDAVA Sbjct: 27 EILLKVTAAGLCHSDITVMDMPAAQYAGGLPLTLGHEGVGTVAELGEGVTGFGVGDAVAV 86 Query: 84 VPLLPCFTCPECLKGFYSQCAKYDFI-----GSRRDGGFAEYIVVKRKNVFALPTDMPIE 138 C C C +G + C + + G G AEY++V D+ Sbjct: 87 YGPWGCGACHACARGRENYCTRAADLGITPPGYGSPGSMAEYMIVDSARHLVPIGDL--- 143 Query: 139 DGAFIEPIT-VGLHAFH-----LAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAID 192 D P+T GL +H L ++IG G +G + IQ A+ A V A+D Sbjct: 144 DPVAAAPLTDAGLTPYHAISRVLPLLGPGSTAVVIGVGGLGHVGIQILRAVSAARVIAVD 203 Query: 193 ISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQ---LILETAGVPQTVELAVEI 249 + ++LALA+ GA S +A +REL Q + + G T++ A ++ Sbjct: 204 LDDDRLALAREVGADAAVKSGAGAA----DAIRELTGGQGATAVFDFVGAQSTIDTAQQV 259 Query: 250 AGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWM-----NYSSPWPGQEWETASR 304 +++VG +H H +G WM + +P+ W T S Sbjct: 260 VAVDGHISVVG-IHAGAHAK--------------VGFWMIPFGASVVTPY----WGTRSE 300 Query: 305 LLTERKLSLEP-LIAHRGSF--ESFAQAVRDIARNAMPGKVLLIP 346 L+ L+ L H +F + A R + ++ G+ +++P Sbjct: 301 LMEVVALARAGRLDIHTETFTLDEGPAAYRRLREGSIRGRGVVVP 345 >2EER-A nrPDB Length = 347 Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 80/332 (24%), Positives = 139/332 (41%), Gaps = 23/332 (6%) Query: 27 EVRVKIASSGLCGSDLP---------RIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHP 77 +V +KI ++G+C SD+ RI ++ P+TLGHE +G I+ VG V Sbjct: 27 QVLIKIEAAGVCHSDVHMRQGRFGNLRIVEDLGVKLPVTLGHEIAGRIEEVGDEVVGYSK 86 Query: 78 GDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKR-KNVFALPTDMP 136 GD VA P C C G C ++G DG +AEY++V K ++ L Sbjct: 87 GDLVAVNPWEGEGNCYYCRIGEEHLCDSPRWLGINYDGAYAEYVLVPHYKYLYKLRRLSA 146 Query: 137 IEDGAFIEPITVGLHAFHLAQGCENKNVIIIGA-GTIGLLAIQCAVALGAKSVTAIDISS 195 +E A A +K +++IGA G +G +AIQ A A+ ++ +D+ Sbjct: 147 VEAAPLTCSGVTTYRAVRKASLDPSKTLVVIGAGGGLGTMAIQIAKAVSGATIIGVDVRE 206 Query: 196 EKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQ 255 E L AK GA N+S + + + +++ +T+ + + + Sbjct: 207 EALEAAKRAGADYVINASSQDPVSEIRRITQGKGADAVIDLNNSEKTLSIYPYVLAKQGK 266 Query: 256 LALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPG-QEWETASRLLTERKLSLE 314 +VG DL + I E+ IGS + S + G A + ++ Sbjct: 267 YVMVGLFGADLKYHAPL---ITLNEVQFIGSLVGNQSDFLGIMSLAEAGK--------VK 315 Query: 315 PLIAHRGSFESFAQAVRDIARNAMPGKVLLIP 346 P++ E +A+ ++ G+ +L+P Sbjct: 316 PMVTKTMKLEEANEAIDNLENFKAVGRQVLVP 347 >1U3W-A nrPDB Length = 374 Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 67/226 (29%), Positives = 102/226 (45%), Gaps = 28/226 (12%) Query: 27 EVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPL 86 EVR+K+ ++G+C SD + N P+ LGHE +G +++VG GV + PGD V +PL Sbjct: 35 EVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKV--IPL 92 Query: 87 LP--CFTCPECLKGFYSQCAKYDF---IGSRRDG------------------GFAEYIVV 123 C C C + C K D G+ +DG F++Y VV Sbjct: 93 FTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVV 152 Query: 124 KRKNVFALPTDMPIEDGAFIE-PITVGL-HAFHLAQGCENKNVIIIGAGTIGLLAIQCAV 181 V + P+E I + G A +A+ + G G +GL + Sbjct: 153 DENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCK 212 Query: 182 ALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLREL 227 A GA + A+DI+ +K A AK GA + N + P +Q VL+E+ Sbjct: 213 AAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP-IQEVLKEM 257 >1HSZ-A nrPDB Length = 374 Score = 86.7 bits (213), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 67/226 (29%), Positives = 103/226 (45%), Gaps = 28/226 (12%) Query: 27 EVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPL 86 EVR+K+ + G+C +D + N P+ LGHE +G +++VG GV + PGD V +PL Sbjct: 35 EVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKV--IPL 92 Query: 87 LP--CFTCPECLKGFYSQCAKYDF---IGSRRDG------------------GFAEYIVV 123 C C C + C K D G+ +DG F++Y VV Sbjct: 93 FTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVV 152 Query: 124 KRKNVFALPTDMPIEDGAFIE-PITVGL-HAFHLAQGCENKNVIIIGAGTIGLLAIQCAV 181 V + P+E I + G A ++A+ + G G +GL A+ Sbjct: 153 DENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCK 212 Query: 182 ALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLREL 227 A GA + A+DI+ +K A AK GA + N + P +Q VL+E+ Sbjct: 213 AAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP-IQEVLKEM 257 >4Z6K-A nrPDB Length = 346 Score = 85.5 bits (210), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 65/193 (33%), Positives = 95/193 (49%), Gaps = 11/193 (5%) Query: 27 EVRVKIASSGLCGSDLPRIFKNG--AHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACV 84 E+ VK+ +SG+C +DL + + P GHE G I AVG GV + GD V Sbjct: 27 EIVVKMQASGVCHTDLHAVEGDWPVKPSPPFIPGHEGVGLITAVGEGVTHVKEGDRVGVA 86 Query: 85 PLLP-CFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAFI 143 L C C CL G+ + C G +G FAEY++ V +P + D I Sbjct: 87 WLYSACGHCTHCLGGWETLCESQQNSGYSVNGSFAEYVLANANYVGIIPESV---DSIEI 143 Query: 144 EPI-TVGLHAFHLAQGCENKN---VIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLA 199 P+ G+ + + + K V+I G G +G +A+Q A+A+G +V A+DI +KLA Sbjct: 144 APVLCAGVTVYKGLKMTDTKPGDWVVISGIGGLGHMAVQYAIAMGL-NVAAVDIDDDKLA 202 Query: 200 LAKSFGAMQTFNS 212 AK GA T N+ Sbjct: 203 FAKKLGAKVTVNA 215 >4RQU-A nrPDB Length = 375 Score = 85.1 bits (209), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 95/346 (27%), Positives = 143/346 (41%), Gaps = 47/346 (13%) Query: 18 VIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAH-YYPITLGHEFSGYIDAVGSGVDDLH 76 V P KH EVR+KI + LC +D+ G +P GHE G +++VG GV DL Sbjct: 25 VAPPQKH--EVRIKILFTSLCHTDVYFWEAKGQTPLFPRIFGHEAGGIVESVGEGVTDLQ 82 Query: 77 PGDAVACVPLLPCFT--CPECLKGFYSQCAKYDF--IGSRRDG----------------- 115 PGD V LP FT C EC + D I + R G Sbjct: 83 PGDHV-----LPIFTGECGECRHCHSEESNMCDLLRINTERGGMIHDGESRFSINGKPIY 137 Query: 116 ------GFAEYIVVKRKNVFALPTDMPIEDGAFIE-PITVGLHA-FHLAQGCENKNVIII 167 F+EY VV V + D P++ + ++ GL A ++A+ + ++V I Sbjct: 138 HFLGTSTFSEYTVVHSGQVAKINPDAPLDKVCIVSCGLSTGLGATLNVAKPKKGQSVAIF 197 Query: 168 GAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLREL 227 G G +GL A + A GA + +D +S++ AK FG + N + P +Q V+ E+ Sbjct: 198 GLGAVGLGAAEGARIAGASRIIGVDFNSKRFDQAKEFGVTECVNPKDHDKP-IQQVIAEM 256 Query: 228 RFNQL--ILETAGVPQTVELAVEIAGPHAQLA-LVGTLHQDLHLTSATFGKILRKELTVI 284 + +E G Q + A E +A LVG +D + E T+ Sbjct: 257 TDGGVDRSVECTGSVQAMIQAFECVHDGWGVAVLVGVPSKDDAFKTHPMN--FLNERTLK 314 Query: 285 GSWM-NYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQA 329 G++ NY P + ++L LE I H F +A Sbjct: 315 GTFFGNYK---PKTDIPGVVEKYMNKELELEKFITHTVPFSEINKA 357 >3PII-A nrPDB Length = 339 Score = 84.3 bits (207), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 74/229 (32%), Positives = 104/229 (45%), Gaps = 20/229 (8%) Query: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAH-------YYPI 55 +VV +++ E P I + EV V+I + G+C +DL + AH P+ Sbjct: 4 AVVEQFKEPLKIKEVEKPTISY-GEVLVRIKACGVCHTDL-----HAAHGDWPVKPKLPL 57 Query: 56 TLGHEFSGYIDAVGSGVDDLHPGDAVACVPLL--PCFTCPECLKGFYSQCAKYDFIGSRR 113 GHE G ++ VG GV L GD V +P L C C CL G + C G Sbjct: 58 IPGHEGVGIVEEVGPGVTHLKVGDRVG-IPWLYSACGHCDYCLSGQETLCEHQKNAGYSV 116 Query: 114 DGGFAEYIVVKRKNVFALPTDMPIEDGA--FIEPITVGLHAFHLAQGCENKNVIIIGAGT 171 DGG+AEY V +P ++ E+ A F +T A + + V I G G Sbjct: 117 DGGYAEYCRAAADYVVKIPDNLSFEEAAPIFCAGVTT-YKALKVTGAKPGEWVAIYGIGG 175 Query: 172 IGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQM 220 G +A+Q A A+G +V A+DI EKL LAK GA N + A + Sbjct: 176 FGHVAVQYAKAMGL-NVVAVDIGDEKLELAKELGADLVVNPLKEDAAKF 223 >5YLN-A nrPDB Length = 356 Score = 84.0 bits (206), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 76/271 (28%), Positives = 117/271 (43%), Gaps = 14/271 (5%) Query: 1 MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPIT-LGH 59 MK+ G+ + P I+ + V+I + +CG+DL I + T LGH Sbjct: 5 MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHIIKGDVPTCQSGTILGH 64 Query: 60 EFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYD--FIGSRRDGGF 117 E G ++ VG GV + GD V + C C C KG Y+ C G DG Sbjct: 65 EGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYAHCEDEGGWIFGHLIDGMQ 124 Query: 118 AEYIVVKRKN--VFALPTDMPIEDGAFIEPI-----TVGLHAFHLAQGCENKNVIIIGAG 170 AEY+ V + ++ P D+ E + I +G+ + GC +V IIG+G Sbjct: 125 AEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGVLKGKVEPGC---SVAIIGSG 181 Query: 171 TIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSE-MSAPQMQSVLRELRF 229 +GL A+ A + +D+ +L A SFGA NSS+ A + L + R Sbjct: 182 PVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVNSSDPEKAIKEIYDLTDGRG 241 Query: 230 NQLILETAGVPQTVELAVEIAGPHAQLALVG 260 + +E G+P T + +I G +A G Sbjct: 242 VDVAIEAVGIPATFDFCQKIIGVDGTVANCG 272 >4DLA-A nrPDB Length = 396 Score = 82.4 bits (202), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 67/229 (29%), Positives = 101/229 (44%), Gaps = 32/229 (13%) Query: 27 EVRVKIASSGLCGSD-LPRIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVP 85 EVRVK+ + LC +D K+ +P LGHE +G +++VG GV ++ PGD V Sbjct: 53 EVRVKVLYTALCHTDAYTWSGKDPEGLFPCVLGHEAAGIVESVGEGVTEVQPGDHVIPCY 112 Query: 86 LLPCFTCPECLKGFYSQCAK-------------------------YDFIGSRRDGGFAEY 120 C C C G + C K Y F+G+ F++Y Sbjct: 113 QAECRECKFCKSGKTNLCGKVRAATGVGVMMNDRKSRFSINGKPIYHFMGTST---FSQY 169 Query: 121 IVVKRKNVFALPTDMPIEDGAFIE-PITVGLHAFHLAQGCENKNVI-IIGAGTIGLLAIQ 178 VV +V + P+E + + GL A E +++ + G GT+GL + Sbjct: 170 TVVHDVSVAKIDPVAPLEKVCLLGCGVPTGLGAVWNTAKVEPGSIVAVFGLGTVGLAVAE 229 Query: 179 CAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLREL 227 A A GA + IDI S+K AK+FG + N E P +Q V+ +L Sbjct: 230 GAKAAGASRIIGIDIDSKKFDRAKNFGVTEFINPKEHEQP-IQQVIVDL 277 >3WLE-A nrPDB Length = 341 Score = 80.1 bits (196), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 89/328 (27%), Positives = 153/328 (46%), Gaps = 32/328 (9%) Query: 27 EVRVKIASSGLCGSDLPRIFKN---GAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVAC 83 ++ +K+ + GLC SDL I++ G +Y +GHE +G + AVG V + GD VAC Sbjct: 38 QLLLKVDAVGLCHSDLHVIYEGLDCGDNY---VMGHEIAGTVAAVGDDVINYKVGDRVAC 94 Query: 84 VPLLPCFTCPECLKGFYSQC--AKYDFIGSRRDGGFAEYIVVKR-KNVFALPTDMPIE-D 139 V C C C + C A D+ G DGG+ +Y++V R +N+ +P ++ + Sbjct: 95 VGPNGCGGCKYCRGAIDNVCKNAFGDWFGLGYDGGYQQYLLVTRPRNLSRIPDNVSADVA 154 Query: 140 GAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLA 199 A + + HA +AQ N+++IGAG +G AIQ A A GAK VT +D E Sbjct: 155 AASTDAVLTPYHAIKMAQVSPTSNILLIGAGGLGGNAIQVAKAFGAK-VTVLDKKKEARD 213 Query: 200 LAKSFGAMQTFNS-SEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLAL 258 AK GA + + E +P S + V T ++ + P + Sbjct: 214 QAKKLGADAVYETLPESISPGSFSA---------CFDFVSVQATFDVCQKYVEPKGVIMP 264 Query: 259 VGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIA 318 VG +L S G + +E+ ++GS+ ++ + + +L++E K ++P++ Sbjct: 265 VGLGAPNL---SFNLGDLALREIRILGSFWGTTN-----DLDDVLKLVSEGK--VKPVV- 313 Query: 319 HRGSFESFAQAVRDIARNAMPGKVLLIP 346 + + + + NA G+V+ P Sbjct: 314 RSAKLKELPEYIEKLRNNAYEGRVVFNP 341 >4JJI-A nrPDB Length = 378 Score = 79.0 bits (193), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 66/229 (28%), Positives = 100/229 (43%), Gaps = 32/229 (13%) Query: 27 EVRVKIASSGLCGSD-LPRIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVP 85 EVR+KI + LC +D K+ +P LGHE +G +++VG GV ++ GD V Sbjct: 35 EVRIKILYTALCHTDAYTWSGKDPEGLFPCILGHEAAGIVESVGEGVTEVQAGDHVIPCY 94 Query: 86 LLPCFTCPECLKGFYSQCAK-------------------------YDFIGSRRDGGFAEY 120 C C C G + C K Y F+G+ F++Y Sbjct: 95 QAECRECKFCKSGKTNLCGKVRSATGVGIMMNDRKSRFSVNGKPIYHFMGTST---FSQY 151 Query: 121 IVVKRKNVFALPTDMPIEDGAFIE-PITVGLHA-FHLAQGCENKNVIIIGAGTIGLLAIQ 178 VV +V + P++ + + GL A ++ A+ NV I G GT+GL + Sbjct: 152 TVVHDVSVAKIDPTAPLDKVCLLGCGVPTGLGAVWNTAKVEPGSNVAIFGLGTVGLAVAE 211 Query: 179 CAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLREL 227 A GA + IDI S+K AK FG + N + P +Q V+ +L Sbjct: 212 GAKTAGASRIIGIDIDSKKYETAKKFGVNEFVNPKDHDKP-IQEVIVDL 259 >1EE2-A nrPDB Length = 373 Score = 78.2 bits (191), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 81/350 (23%), Positives = 145/350 (41%), Gaps = 45/350 (12%) Query: 27 EVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPL 86 EVR+K+ ++G+C SD + P+ GHE +G ++++G GV + PGD V + + Sbjct: 35 EVRIKMVAAGICRSDDHVVSGTLVAPLPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFI 94 Query: 87 LPCFTCPECLKGFYSQCAKYDFI--GSRRDGG------------------FAEYIVVKRK 126 C C C + C K + G+ +DG F++Y VV Sbjct: 95 PQCGKCSVCKHPEGNLCLKNLSMPRGTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEI 154 Query: 127 NVFALPTDMPIEDGAFIE-PITVGL-HAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALG 184 +V + P+E + + G A +A+ + + G G +GL I A G Sbjct: 155 SVAKIDAASPLEKVCLVGCGFSTGYGSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAG 214 Query: 185 AKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVE 244 A + +DI+ +K A AK GA + N + P +Q VL E+ V+ Sbjct: 215 AARIIGVDINKDKFAKAKEVGATECVNPQDYKKP-IQEVLTEMSNGG-----------VD 262 Query: 245 LAVEIAGPHAQLALVGTLHQDLHLTSATFG-KILRKELTVIGSWMNYSSPWPG------Q 297 + E+ G + + Q+ + S G + L++ + W G + Sbjct: 263 FSFEVIGRLDTMVAALSCCQEAYGVSVIVGVPPDSQNLSMNPMLLLSGRTWKGAIFGGFK 322 Query: 298 EWETASRLLTE---RKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 ++ +L+ + +K +L+PLI H FE + D+ R+ + +L Sbjct: 323 SKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGF-DLLRSGKSIRTIL 371 >1KEV-A nrPDB Length = 351 Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 64/223 (28%), Positives = 93/223 (41%), Gaps = 9/223 (4%) Query: 38 CGSDLPRIFKNG-AHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECL 96 C SD+ +F+ + LGHE G + VGS V D PGD V P + E Sbjct: 37 CTSDIHTVFEGALGDRKNMILGHEAVGEVVEVGSEVKDFKPGDRVIVPCTTPDWRSLEVQ 96 Query: 97 KGFYSQC----AKYDFIGSRRDGGFAEYIVVKRK--NVFALPTDMPIEDGAFI-EPITVG 149 GF A + F + +DG F EY V N+ LP DMP+E+ I + +T G Sbjct: 97 AGFQQHSNGMLAGWKF-SNFKDGVFGEYFHVNDADMNLAILPKDMPLENAVMITDMMTTG 155 Query: 150 LHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQT 209 H LA +V++IG G +GL+ I A GA + + + AK +GA Sbjct: 156 FHGAELADIQMGSSVVVIGIGAVGLMGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDI 215 Query: 210 FNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGP 252 N L + ++ G +T+ AV + P Sbjct: 216 LNYKNGHIVDQVMKLTNGKGVDRVIMAGGGSETLSQAVSMVKP 258 >1MC5-A nrPDB Length = 374 Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 84/338 (24%), Positives = 138/338 (40%), Gaps = 48/338 (14%) Query: 27 EVRVKIASSGLCGSDLPRIFKNGAH---YYPITLGHEFSGYIDAVGSGVDDLHPGDAVAC 83 EVR+KI ++ +C +D + +GA +P+ LGHE +G +++VG GV L GD V Sbjct: 34 EVRIKIIATAVCHTDAYTL--SGADPEGCFPVILGHEGAGIVESVGEGVTKLKAGDTVIP 91 Query: 84 VPLLPCFTCPECLKGFYSQCAKYDFI---GSRRDG------------------GFAEYIV 122 + + C C CL + C K G DG F+EY V Sbjct: 92 LYIPQCGECKFCLNPKTNLCQKIRVTQGKGLMPDGTSRFTCKGKTILHYMGTSTFSEYTV 151 Query: 123 VKRKNVFALPTDMPIEDGAFIE-PITVGLHAFHLAQGCENKNVI-IIGAGTIGLLAIQCA 180 V +V + P++ + I+ G A E +V + G G +GL I Sbjct: 152 VADISVAKIDPLAPLDKVCLLGCGISTGYGAAVNTAKLEPGSVCAVFGLGGVGLAVIMGC 211 Query: 181 VALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVP 240 GA + +DI+ +K A AK FGA + N + S P +Q VL E+ GV Sbjct: 212 KVAGASRIIGVDINKDKFARAKEFGATECINPQDFSKP-IQEVLIEMT-------DGGVD 263 Query: 241 QTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEW- 299 + E I A + H+ ++ +E+ + W G + Sbjct: 264 YSFEC---IGNVKVMRAALEACHKGWGVSVVVGVAASGEEIATRPFQLVTGRTWKGTAFG 320 Query: 300 -----ETASRLLTE---RKLSLEPLIAHRGSFESFAQA 329 E+ +L++E +K+ ++ + H SF+ +A Sbjct: 321 GWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKA 358 >3FSR-A nrPDB Length = 352 Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 60/223 (26%), Positives = 96/223 (43%), Gaps = 9/223 (4%) Query: 38 CGSDLPRIFKNG-AHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECL 96 C SD+ +F+ + + LGHE G + VGS V D PGD V + P + E Sbjct: 37 CTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVKDFKPGDRVVVPAITPDWRTSEVQ 96 Query: 97 KGFYSQC----AKYDFIGSRRDGGFAEYIVVKRK--NVFALPTDMPIEDGAFI-EPITVG 149 +G++ A + F + +DG F E+ V N+ LP ++P+E I + +T G Sbjct: 97 RGYHQHSGGMLAGWKF-SNVKDGVFGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTG 155 Query: 150 LHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQT 209 H LA +V++IG G +GL+ I A GA + + + AK +GA Sbjct: 156 FHGAELADIQMGSSVVVIGIGAVGLMGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDI 215 Query: 210 FNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGP 252 N L + ++ G +T+ AV + P Sbjct: 216 LNYKNGHIVDQVMKLTNGKGVDRVIMAGGGSETLSQAVSMVKP 258 >1R37-A nrPDB Length = 347 Score = 75.5 bits (184), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 87/344 (25%), Positives = 145/344 (42%), Gaps = 47/344 (13%) Query: 27 EVRVKIASSGLCGSDLP---------RIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHP 77 +V +K+ ++G+C SD+ RI ++ P+TLGHE +G I+ VG V Sbjct: 27 QVLIKVEAAGVCHSDVHMRQGRFGNLRIVEDLGVKLPVTLGHEIAGKIEEVGDEVVGYSK 86 Query: 78 GDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKR-KNVFALPTDMP 136 GD VA P C C G C ++G DG +AEY++V K ++ L Sbjct: 87 GDLVAVNPWQGEGNCYYCRIGEEHLCDSPRWLGINFDGAYAEYVIVPHYKYMYKLRRLNA 146 Query: 137 IEDGAFIEPITV-GLHAFHLAQGCE----NKNVIIIGAGTIGLLAIQCAVALGAKSVTAI 191 +E P+T G+ + + +++ G +G +A+Q A A+ ++ + Sbjct: 147 VEAA----PLTCSGITTYRAVRKASLDPTKTLLVVGAGGGLGTMAVQIAKAVSGATIIGV 202 Query: 192 DISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAV---- 247 D+ E + AK GA N+S MQ L E+R I E+ GV ++L Sbjct: 203 DVREEAVEAAKRAGADYVINAS------MQDPLAEIR---RITESKGVDAVIDLNNSEKT 253 Query: 248 -----EIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETA 302 + + +VG DLH + I E+ +GS + S + G Sbjct: 254 LSVYPKALAKQGKYVMVGLFGADLHYHAPL---ITLSEIQFVGSLVGNQSDFLG-----I 305 Query: 303 SRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP 346 RL K ++P+I E +A+ ++ G+ +LIP Sbjct: 306 MRLAEAGK--VKPMITKTMKLEEANEAIDNLENFKAIGRQVLIP 347 >6N7L-A nrPDB Length = 353 Score = 75.5 bits (184), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 66/195 (33%), Positives = 96/195 (49%), Gaps = 14/195 (7%) Query: 27 EVRVKIASSGLCGSDLPRIFKN--GAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACV 84 EV VK+ + G+C +DL + + P+ GHE G + A G + GDAV V Sbjct: 40 EVLVKVMACGVCHTDLHAVDGDWPAKPKMPLIPGHEGVGIVVACGPDAM-VKEGDAVG-V 97 Query: 85 PLL--PCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAF 142 P L C C C+ G+ + C G DGGFAEY++ + V L +++ + Sbjct: 98 PWLYSACGCCDYCITGWETLCEAQQNGGYSVDGGFAEYVIADSRYVGHLKSNVNFLE--- 154 Query: 143 IEPI-TVGLHAFHLAQGCENKN---VIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKL 198 I PI G+ + + E K V I G G +G +A+Q A A+G V AID++ +KL Sbjct: 155 IAPILCAGVTVYKGLKETETKPGEWVAISGIGGLGHVAVQYAKAMGM-HVAAIDVADDKL 213 Query: 199 ALAKSFGAMQTFNSS 213 LAK GA T N+ Sbjct: 214 ELAKKLGADLTVNAK 228 >4EEZ-A nrPDB Length = 348 Score = 75.5 bits (184), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 65/220 (29%), Positives = 99/220 (45%), Gaps = 5/220 (2%) Query: 1 MKSVV--NDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLG 58 MK+ V ++ DG + E + IK +E + + G+C +DL + + LG Sbjct: 1 MKAAVVRHNPDGYADLVEKELRAIK-PNEALLDMEYCGVCHTDLHVAAGDFGNKAGTVLG 59 Query: 59 HEFSGYIDAVGSGVDDLHPGDAVACVPLLP-CFTCPECLKGFYSQCAKYDFIGSRRDGGF 117 HE G + +G+ V L GD V+ C C C+ G + C + G DGG Sbjct: 60 HEGIGIVKEIGADVSSLQVGDRVSVAWFFEGCGHCEYCVSGNETFCREVKNAGYSVDGGM 119 Query: 118 AEYIVVKRKNVFALPTDM-PIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLA 176 AE +V +P + PIE + A ++ +I GAG +G LA Sbjct: 120 AEEAIVVADYAVKVPDGLDPIEASSITCAGVTTYKAIKVSGVKPGDWQVIFGAGGLGNLA 179 Query: 177 IQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMS 216 IQ A + V A+DI+ +KL LAK GA T NS +++ Sbjct: 180 IQYAKNVFGAKVIAVDINQDKLNLAKKIGADVTINSGDVN 219 >3FPL-A nrPDB Length = 351 Score = 74.7 bits (182), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 67/230 (29%), Positives = 96/230 (41%), Gaps = 9/230 (3%) Query: 38 CGSDLPRIFKNG-AHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECL 96 C SD+ +F+ + LGHE G + VGS V D PGD V P + E Sbjct: 37 CTSDIHTVFEGALGDRKNMILGHEAVGEVVEVGSEVKDFKPGDRVIVPCTTPDWRSLEVQ 96 Query: 97 KGFYSQC----AKYDFIGSRRDGGFAEYIVVKRK--NVFALPTDMPIEDGAFI-EPITVG 149 GF A + F + +DG F EY V N+ LP DMP+E+ I + +T G Sbjct: 97 AGFQQHSNGMLAGWKF-SNFKDGVFGEYFHVNDADMNLAILPKDMPLENAVMITDMMTTG 155 Query: 150 LHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQT 209 H LA V ++G G +GL+A+ A GA + A+ + AK +GA Sbjct: 156 FHGAELADIELGATVAVLGIGPVGLMAVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDI 215 Query: 210 FNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALV 259 N + L E + + G + AV+I P +A V Sbjct: 216 VNYKDGPIESQIMNLTEGKGVDAAIIAGGNADIMATAVKIVKPGGTIANV 265 >1YKF-A nrPDB Length = 352 Score = 74.3 bits (181), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 63/230 (27%), Positives = 99/230 (43%), Gaps = 9/230 (3%) Query: 38 CGSDLPRIFKNG-AHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECL 96 C SD+ +F+ + + LGHE G + VGS V D PGD V + P + E Sbjct: 37 CTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVKDFKPGDRVVVPAITPDWRTSEVQ 96 Query: 97 KGFYSQC----AKYDFIGSRRDGGFAEYIVVKRK--NVFALPTDMPIEDGAFI-EPITVG 149 +G++ A + F + +DG F E+ V N+ LP ++P+E I + +T G Sbjct: 97 RGYHQHSGGMLAGWKF-SNVKDGVFGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTG 155 Query: 150 LHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQT 209 H LA V ++G G +GL+A+ A GA + A+ + AK +GA Sbjct: 156 FHGAELADIELGATVAVLGIGPVGLMAVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDI 215 Query: 210 FNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALV 259 N + L E + + G + AV+I P +A V Sbjct: 216 VNYKDGPIESQIMNLTEGKGVDAAIIAGGNADIMATAVKIVKPGGTIANV 265 >1D1T-A nrPDB Length = 373 Score = 74.3 bits (181), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 61/234 (26%), Positives = 98/234 (41%), Gaps = 35/234 (14%) Query: 27 EVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPL 86 EVR+KI ++G+C +D I +P+ +GHE +G ++++G GV + PGD V + L Sbjct: 35 EVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFL 94 Query: 87 LPCFTCPECLKGFYSQCAKYDFIGS--RRDG------------------GFAEYIVVKRK 126 C C C + C + D G DG F EY VV Sbjct: 95 PQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFLNTSTFTEYTVVDES 154 Query: 127 NVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENK--------NVIIIGAGTIGLLAIQ 178 +V I+D A E + + F G K ++ G G +GL I Sbjct: 155 SV------AKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIM 208 Query: 179 CAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQL 232 + GA + ID++ +K A + GA + + + + P + VL E+ N + Sbjct: 209 GCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKP-ISEVLSEMTGNNV 261 >3FPC-A nrPDB Length = 352 Score = 73.9 bits (180), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 54/182 (29%), Positives = 84/182 (46%), Gaps = 9/182 (4%) Query: 38 CGSDLPRIFKNG-AHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECL 96 C SD+ +F+ + + LGHE G + VGS V D PGD V + P + E Sbjct: 37 CTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVKDFKPGDRVVVPAITPDWRTSEVQ 96 Query: 97 KGFYSQC----AKYDFIGSRRDGGFAEYIVVKRK--NVFALPTDMPIEDGAFI-EPITVG 149 +G++ A + F + +DG F E+ V N+ LP ++P+E I + +T G Sbjct: 97 RGYHQHSGGMLAGWKF-SNVKDGVFGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTG 155 Query: 150 LHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQT 209 H LA V +IG G +GL+++ A LGA + A+ +A +GA Sbjct: 156 FHGAELANIKLGDTVCVIGIGPVGLMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDI 215 Query: 210 FN 211 N Sbjct: 216 IN 217 >1YQX-A nrPDB Length = 366 Score = 71.2 bits (173), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 77/256 (30%), Positives = 119/256 (46%), Gaps = 18/256 (7%) Query: 25 QDEVRVKIASSGLCGSDLPRIFKN-GAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVAC 83 +++VR K+ G+C SDL I + G YP+ GHE G + VGS V ++ GD V Sbjct: 41 EEDVRFKVLYCGVCHSDLHSIKNDWGFSMYPLVPGHEIVGEVTEVGSKVKKVNVGDKVGV 100 Query: 84 VPLL-PCFTCPECLKGFYSQCAK----YDFI---GSRRDGGFAEYIVVKRKNVFALPTDM 135 L+ C +C C + C K Y I G+ GG++ ++V + + P +M Sbjct: 101 GCLVGACHSCESCANDLENYCPKMILTYASIYHDGTITYGGYSNHMVANERYIIRFPDNM 160 Query: 136 PIEDGA--FIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDI 193 P++ GA ITV + K++ I+G G +G +A++ A A G+K VT I Sbjct: 161 PLDGGAPLLCAGITVYSPLKYFGLDEPGKHIGIVGLGGLGHVAVKFAKAFGSK-VTVIST 219 Query: 194 S-SEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGP 252 S S+K K+FGA S + QMQ+ L I++T + + Sbjct: 220 SPSKKEEALKNFGADSFLVSRDQE--QMQAAAGTL---DGIIDTVSAVHPLLPLFGLLKS 274 Query: 253 HAQLALVGTLHQDLHL 268 H +L LVG + L L Sbjct: 275 HGKLILVGAPEKPLEL 290 >1P0F-A nrPDB Length = 373 Score = 70.1 bits (170), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 66/260 (25%), Positives = 105/260 (40%), Gaps = 35/260 (13%) Query: 17 SVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLH 76 +V P H EVR+KI +SG+CGSD + + +P+ LGHE G ++++G+GV + Sbjct: 28 TVAPPKAH--EVRIKILASGICGSDSSVLKEIIPSKFPVILGHEAVGVVESIGAGVTCVK 85 Query: 77 PGDAVACVPLL--PCFTCPECLKGFYSQCAK------------------------YDFIG 110 PGD V +PL C +C C + C K Y+ +G Sbjct: 86 PGDKV--IPLFVPQCGSCRACKSSNSNFCEKNDMGAKTGLMADMTSRFTCRGKPIYNLMG 143 Query: 111 SRRDGGFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGL-HAFHLAQGCENKNVIIIGA 169 + F EY VV V + P+E G A + A+ + G Sbjct: 144 TST---FTEYTVVADIAVAKIDPKAPLESCLIGCGFATGYGAAVNTAKVTPGSTCAVFGL 200 Query: 170 GTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRF 229 G +G AI A GA + + +K A GA + N + P + + + Sbjct: 201 GGVGFSAIVGCKAAGASRIIGVGTHKDKFPKAIELGATECLNPKDYDKPIYEVICEKTNG 260 Query: 230 N-QLILETAGVPQTVELAVE 248 +E AG +T+ A++ Sbjct: 261 GVDYAVECAGRIETMMNALQ 280 >2H6E-A nrPDB Length = 344 Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 58/188 (30%), Positives = 88/188 (46%), Gaps = 13/188 (6%) Query: 19 IPEIKHQDEVRVKIASSGLCGSDLPRIFK----NGAHYYPITLGHEFSGYIDAVGSGVDD 74 IPE +EV ++I +G+C +DL R++K PI LGHE +G I VG + Sbjct: 23 IPE-PQGEEVLIRIGGAGVCRTDL-RVWKGVEAKQGFRLPIILGHENAGTIVEVGE-LAK 79 Query: 75 LHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKN-VFALPT 133 + GD V TC C +G ++ C G +GGF+EY++VK + L + Sbjct: 80 VKKGDNVVVYATWGDLTCRYCREGKFNICKNQIIPGQTTNGGFSEYMLVKSSRWLVKLNS 139 Query: 134 DMPIEDGAFIEPITVGLHAFHLAQGCENK----NVIIIGAGTIGLLAIQCAVALGAKSVT 189 P+E + T + A A +K VI+ G G + + IQ AL K++T Sbjct: 140 LSPVEAAPLADAGTTSMGAIRQALPFISKFAEPVVIVNGIGGLAVYTIQILKAL-MKNIT 198 Query: 190 AIDISSEK 197 + IS K Sbjct: 199 IVGISRSK 206 >1UUF-A nrPDB Length = 369 Score = 65.1 bits (157), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 78/272 (28%), Positives = 121/272 (44%), Gaps = 31/272 (11%) Query: 26 DEVRVKIASSGLCGSDLPRIFKNGA-HYYPITLGHEFSGYIDAVGSGVDDLHPGD--AVA 82 ++V+++IA G+C SDL ++ A YP GHE G + AVG V+ PGD V Sbjct: 48 NDVKIEIAYCGVCHSDLHQVRSEWAGTVYPCVPGHEIVGRVVAVGDQVEKYAPGDLVGVG 107 Query: 83 CVPLLPCFTCPECLKGFYSQCAKYDFIGSRRD----------GGFAEYIVVKRKNVFALP 132 C+ + C C EC G + C G+ GG+++ IVV + + L Sbjct: 108 CI-VDSCKHCEECEDGLENYCDH--MTGTYNSPTPDEPGHTLGGYSQQIVVHER--YVLR 162 Query: 133 TDMPIEDGAFIEP-ITVGLHAF----HLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKS 187 P E A + P + G+ + H G K V ++G G +G + I+ A A+GA Sbjct: 163 IRHPQEQLAAVAPLLCAGITTYSPLRHWQAG-PGKKVGVVGIGGLGHMGIKLAHAMGAH- 220 Query: 188 VTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAV 247 V A S K AK+ GA + NS +A +M + L+ F IL T P ++ Sbjct: 221 VVAFTTSEAKREAAKALGADEVVNSR--NADEMAAHLKSFDF---ILNTVAAPHNLDDFT 275 Query: 248 EIAGPHAQLALVGTLHQDLHLTSATFGKILRK 279 + + LVG H + F I+++ Sbjct: 276 TLLKRDGTMTLVGAP-ATPHKSPEVFNLIMKR 306 >2OUI-A nrPDB Length = 360 Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 85/332 (25%), Positives = 133/332 (40%), Gaps = 23/332 (6%) Query: 10 GIVRVA--ESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNG-AHYYPITLGHEFSGYID 66 GI R+ E IPE D + V+ + C SD ++ + + LGHE G I Sbjct: 8 GIGRIGWIEKKIPECGPLDAL-VRPLALAPCTSDTHTVWAGAIGDRHDMILGHEAVGQIV 66 Query: 67 AVGSGVDDLHPGDAVACVPLLPCFTCPECLKGF----YSQCAKYDFIGSRRDGGFAEYIV 122 VGS V L GD V + P + E +G+ + F + +DG F+E Sbjct: 67 KVGSLVKRLKVGDKVIVPAITPDWGEEESQRGYPMHSGGMLGGWKF-SNFKDGVFSEVFH 125 Query: 123 VKRK--NVFALPTDMPIEDGAFI-EPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQC 179 V N+ LP D+ ED + + +T G H LA V +IG G +GL+++ Sbjct: 126 VNEADANLALLPRDIKPEDAVMLSDMVTTGFHGAELANIKLGDTVCVIGIGPVGLMSVAG 185 Query: 180 AVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGV 239 A LGA + A+ +A +GA N + + + ++ G Sbjct: 186 ANHLGAGRIFAVGSRKHCCDIALEYGATDIINYKNGDIVEQILKATDGKGVDKVVIAGGD 245 Query: 240 PQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTV-IGSWMNYSSPWPGQ- 297 T AV++ P + + V L + ++ I R E V +G + PG Sbjct: 246 VHTFAQAVKMIKPGSDIGNVNYLGEGDNIP------IPRSEWGVGMGHKHIHGGLTPGGR 299 Query: 298 -EWETASRLLTERKLSLEPLIAHRGSFESFAQ 328 E + L++ KL LI HR FE + Sbjct: 300 VRMEKLASLISTGKLDTSKLITHR--FEGLEK 329 >5K1S-A nrPDB Length = 362 Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 75/287 (26%), Positives = 119/287 (41%), Gaps = 47/287 (16%) Query: 25 QDEVRVKIASSGLCGSD-------LPRIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHP 77 + EV +++ + G+C D LPR P LGHE +G + VG Sbjct: 44 RGEVLLRVHACGVCYHDVINRRGNLPRT------SVPAILGHEAAGEVIEVGPDTPGWKT 97 Query: 78 GDAVACVPLLPCFTCPECLKGFYSQCAKYD-FIGSRRDGGFAEYIVVKRKNVFALPTDMP 136 GD A + + C C C G S C + F G GG+A+++V + +P +P Sbjct: 98 GDRAATLQRMSCGDCALCRSGRNSLCKTDNRFFGEELPGGYAQFMVAPVGGLGRVPASLP 157 Query: 137 IEDGAFIEPIT-VGLHAFHLAQGCE-NKNVIIIGA-GTIGLLAIQCAVALGAKSVTAIDI 193 + A + T +H + V+I GA G +GL ++Q A GA+ V A+ Sbjct: 158 WNEAATVCCTTGTAVHTVRTRGKVRAGETVLITGASGGVGLSSVQLARLDGAR-VIAVTS 216 Query: 194 SSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRF-NQLILETAGVPQTVELAVEIAG- 251 S K+ K GA + V R L F + + T G V++AVEI G Sbjct: 217 SEAKVQALKEAGADEVI------------VSRGLDFASDVRKRTQGA--GVDVAVEIVGS 262 Query: 252 -----------PHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSW 287 P ++ +VG L + G ++ KEL ++G++ Sbjct: 263 ATFDQTLKSMAPGGRVVVVGNLESG--MVQLNPGLVIVKELEILGAY 307 >3TWO-A nrPDB Length = 348 Score = 62.0 bits (149), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 79/329 (24%), Positives = 142/329 (43%), Gaps = 42/329 (12%) Query: 27 EVRVKIASSGLCGSDLPRIF---KNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVAC 83 +V + I +G+C SD+ + K G YP+ GHE +G I VG GV GD V Sbjct: 31 DVLIDILYAGICHSDIHSAYSEWKEGI--YPMIPGHEIAGIIKEVGKGVKKFKIGDVVGV 88 Query: 84 VPLL-PCFTCPECLKGFYSQCAK----YDFIGSRRD-----GGFAEYIVVKRKNVFALPT 133 + C C C + C K YD + S D GG++ IVV V ++ Sbjct: 89 GCFVNSCKACKPCKEHQEQFCTKVVFTYDCLDSFHDNEPHMGGYSNNIVVDENYVISVDK 148 Query: 134 DMPIEDGAFIEPITVGLHAF---HLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTA 190 + P+E A + + G+ + ++ + V + G G +G +A++ AVA+GA+ V+ Sbjct: 149 NAPLEKVAPL--LCAGITTYSPLKFSKVTKGTKVGVAGFGGLGSMAVKYAVAMGAE-VSV 205 Query: 191 IDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLR------ELRFNQLILETAGVPQTVE 244 + K A S G + + ++ ++ +L+ +L G + Sbjct: 206 FARNEHKKQDALSMGVKHFYTDPKQCKEELDFIISTIPTHYDLKDYLKLLTYNG-----D 260 Query: 245 LAVEIAGPHAQLALVGTLHQDLHL-TSATFGKILR--KELTVIGSWMNYSSPWP------ 295 LA+ + P ++A V ++ +HL +G ++ KE + + + +P Sbjct: 261 LAL-VGLPPVEVAPVLSVFDFIHLGNRKVYGSLIGGIKETQEMVDFSIKHNIYPEIDLIL 319 Query: 296 GQEWETASRLLTERKLSLEPLIAHRGSFE 324 G++ +TA LT K +I + SF+ Sbjct: 320 GKDIDTAYHNLTHGKAKFRYVIDMKKSFD 348 >4GKV-A nrPDB Length = 336 Score = 61.6 bits (148), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 70/227 (30%), Positives = 96/227 (42%), Gaps = 13/227 (5%) Query: 1 MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNG--AHYYPITLG 58 MK+ V D V V + +KH E +K+ G+C +DL KNG + LG Sbjct: 1 MKAAVVTKDHHVDVTYKTLRSLKHG-EALLKMECCGVCHTDLH--VKNGDFGDKTGVILG 57 Query: 59 HEFSGYIDAVGSGVDDLHPGDAVACVPLLP-CFTCPECLKGFYSQCAKYDFIGSRRDGGF 117 HE G + VG GV L PGD + C C C G + C G DGG Sbjct: 58 HEGIGVVAEVGPGVTSLKPGDRASVAWFYEGCGHCEYCNSGNETLCRSVKNAGYSVDGGM 117 Query: 118 AEYIVVKRKNVFALPTDMPIEDGAFIEPITVG----LHAFHLAQGCENKNVIIIGAGTIG 173 AE +V +P + D A IT A L++ + + I G G +G Sbjct: 118 AEECIVVADYAVKVPDGL---DSAAASSITCAGVTTYKAVKLSKIRPGQWIAIYGLGGLG 174 Query: 174 LLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQM 220 LA+Q A + V AID++ E+L LA GA NS A ++ Sbjct: 175 NLALQYAKNVFNAKVIAIDVNDEQLKLATEMGADLAINSHTEDAAKI 221 >5VKT-A nrPDB Length = 362 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 39/133 (29%), Positives = 60/133 (45%), Gaps = 13/133 (9%) Query: 21 EIKHQDEVRVKIASSGLCGSDLPRIFKN--GAHYYPITLGHEFSGYIDAVGSGVDDLHPG 78 I+ +V +K+ G+C +DL + KN G YP+ GHE G + VG GV G Sbjct: 30 RIQGDADVTIKVLFCGICHTDL-HVIKNEWGNAMYPVVPGHEVVGVVTDVGHGVTKFKAG 88 Query: 79 DAVACVPLL-PCFTCPECLKGFYSQC---------AKYDFIGSRRDGGFAEYIVVKRKNV 128 D V + C TC C G + C + G+ GGF++ +VV + V Sbjct: 89 DTVGVGYFVDSCRTCESCSTGHENYCPDLVLTSNGVDHHHHGATTKGGFSDVLVVSQDFV 148 Query: 129 FALPTDMPIEDGA 141 +P +P++ A Sbjct: 149 VRVPESLPLDGAA 161 >5Z0C-A nrPDB Length = 374 Score = 57.4 bits (137), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 68/255 (26%), Positives = 113/255 (44%), Gaps = 20/255 (7%) Query: 27 EVRVKIASSGLCGSDLPRIFKNGAH-YYPITLGHEFSGYIDAVGSGVDDLHPGD--AVAC 83 +V K+ G+C SDL I ++ YP GHE G + VGS V+ GD V C Sbjct: 40 DVTFKVLYCGICHSDLHYIKNEWSNTIYPALPGHEIVGEVTEVGSKVNKFKVGDKVGVGC 99 Query: 84 VPLLPCFTCPECLKGFYSQC--------AKYDFIGSRRDGGFAEYIVVKRKNVFALPTDM 135 + + C +CP C + C ++Y + G+ GG+++ +VV+ +P + Sbjct: 100 I-VGSCHSCPNCNNHLENYCPNRILTFGSRY-YDGTLNHGGYSDLMVVQEHFAVRIPDAL 157 Query: 136 PIEDGA--FIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDI 193 P++ A ITV + +V ++G G +G +A++ A A G K VT + Sbjct: 158 PLDSAAPLLCAGITVYSPLRYYGLDKPGLHVGVVGLGGLGHMAVKFAKAFGVK-VTVVST 216 Query: 194 SSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPH 253 S K A S +F S A QMQ+ + + I++T + + + H Sbjct: 217 SPAKKEDAISGLGAHSFILS-TDAEQMQAAVGTM---DGIIDTVSASHPLPPLISLLKSH 272 Query: 254 AQLALVGTLHQDLHL 268 +L +VG + L L Sbjct: 273 GKLVMVGDPPKPLEL 287 >5H82-A nrPDB Length = 389 Score = 57.4 bits (137), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 57/209 (27%), Positives = 86/209 (41%), Gaps = 37/209 (17%) Query: 25 QDEVRVKIASSGLCGSDLPRIFKN--GAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVA 82 + +V+ K+ GLC D+ KN G YP GHE G + +G+ V GD V Sbjct: 53 EHDVQFKVLYCGLCDWDVITT-KNTYGTTKYPFVPGHEIMGIVTEIGNKVKKFKVGDKVG 111 Query: 83 CVPLL-PCFTCPECLKGFYSQCAKY-----------------DFIGSRRD---GGFAEYI 121 + C C C +G C K D G D GG++ + Sbjct: 112 VGNFIGSCGKCERCNEGLEPYCPKVIYTDGTAFSDENNTVYGDVSGDGEDRIYGGYSNIM 171 Query: 122 VVKRKNVFALPTDMPIEDGAFIEPITVG-------LHAFHLAQGCENKNVIIIGAGTIGL 174 V VF P ++P+ G PI G + F L + ++ ++G G IG Sbjct: 172 VANEYVVFRWPENLPLAAGV---PILCGGIVPYSPMRHFGLDK--PGLSIGVVGFGRIGK 226 Query: 175 LAIQCAVALGAK-SVTAIDISSEKLALAK 202 LA++ A A GA +V + IS ++ A+ K Sbjct: 227 LAVKFAKAFGANVTVISTSISKKQEAIEK 255 >4OAQ-A nrPDB Length = 367 Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 65/200 (32%), Positives = 91/200 (45%), Gaps = 26/200 (13%) Query: 27 EVRVKIASSGLCGSDLPRIFKNGAHYYPI-----TLGHEFSGYIDAVGSGVDDLHPGDAV 81 +V +K GLC SD+ + A + P+ +GHE G + AVG V + GD V Sbjct: 37 DVVLKNEVCGLCYSDIHTL---SAGWQPLQRDNLVVGHEIIGEVIAVGDEVTEFKVGDRV 93 Query: 82 AC-VPLLPCFTCPECLKGFYSQC----AKYDFIGSRRD-----GGFAEYIVVKRKNVFAL 131 C +C C C A Y+ R + GG++ + + K VFA+ Sbjct: 94 GIGAASSSCRSCQRCDSDNEQYCKQGAATYNSKDVRSNNYVTQGGYSSHSIADEKFVFAI 153 Query: 132 PTDMPIEDGAFIEPITVGLHAF-----HLAQGCENKNVIIIGAGTIGLLAIQCAVALGAK 186 P D+P GA + + G+ F +L KNV IIG G +G LA+Q A A+GA Sbjct: 154 PEDLPSSYGAPL--MCAGITVFSPLIRNLGLDARGKNVGIIGIGGLGHLALQFANAMGA- 210 Query: 187 SVTAIDISSEKLALAKSFGA 206 +VTA SS K A GA Sbjct: 211 NVTAFSRSSSKKEQAMKLGA 230 >3UOG-A nrPDB Length = 363 Score = 55.5 bits (132), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 85/346 (24%), Positives = 136/346 (39%), Gaps = 38/346 (10%) Query: 12 VRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHY---YPITLGHEFSGYIDAV 68 +++AE +PE D + +A S L + + G +P + SG ++AV Sbjct: 41 LKLAERPVPEAGEHDIIVRTLAVSLNYRDKL--VLETGMGLDLAFPFVPASDMSGVVEAV 98 Query: 69 GSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAK---YDFIGSRRDGGFAEYIVVKR 125 G V PGD V + F P L G + Y+ +G G +EY+V+ Sbjct: 99 GKSVTRFRPGDRV-----ISTF-APGWLDGLRPGTGRTPAYETLGGAHPGVLSEYVVLPE 152 Query: 126 KNVFALPTDMPIEDGAFIEPITVGLHAF-------HLAQGCENKNVIIIGAGTIGLLAIQ 178 A P + + + + GL A+ HL G V++ G G + L +Q Sbjct: 153 GWFVAAPKSLDAAEASTLP--CAGLTAWFALVEKGHLRAG---DRVVVQGTGGVALFGLQ 207 Query: 179 CAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAG 238 A A GA+ V S EKL A + GA N E + L R ILE AG Sbjct: 208 IAKATGAE-VIVTSSSREKLDRAFALGADHGINRLEEDWVERVYALTGDRGADHILEIAG 266 Query: 239 VPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQE 298 + +++ P +++++G L S G +L K V G + G Sbjct: 267 -GAGLGQSLKAVAPDGRISVIGVLEG--FEVSGPVGPLLLKSPVVQGISV-------GHR 316 Query: 299 WETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 + +L L+P+I R F +A+ + R GKV++ Sbjct: 317 RALEDLVGAVDRLGLKPVIDMRYKFTEVPEALAHLDRGPF-GKVVI 361 >5YAT-A nrPDB Length = 350 Score = 55.1 bits (131), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 63/216 (29%), Positives = 99/216 (45%), Gaps = 18/216 (8%) Query: 2 KSVVNDTDG-IVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNG---AHYYPITL 57 K+V+ +T+G + + +P+ K +E+ + + SG+C +DL +K + P+ Sbjct: 10 KAVIFETNGGPLEYKDIPVPKPK-SNELLINVKYSGVCHTDL-HAWKGDWPLDNKLPLVG 67 Query: 58 GHEFSGYIDAVGSGVDDLHPGDAVACVPLL--PCFTCPECLKGFYSQCAKYDFIGSRRDG 115 GHE +G + A G V GD A + L C C C++G S CAK D G DG Sbjct: 68 GHEGAGVVVAYGENVTGWEIGD-YAGIKWLNGSCLNCEYCIQGAESSCAKADLSGFTHDG 126 Query: 116 GFAEYIVVKRKNVFALPTDMPIEDGAFIEPI-TVGLHAFHLAQGCENK----NVIIIGAG 170 F +Y +P + D A + PI G+ + + + + I G Sbjct: 127 SFQQYATADATQAARIPKEA---DLAEVAPILCAGITVYKALKTADLRIGQWVAISGAGG 183 Query: 171 TIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGA 206 +G LA+Q A ALG + V ID ++K KS GA Sbjct: 184 GLGSLAVQYAKALGLR-VLGIDGGADKGEFVKSLGA 218 >5H83-A nrPDB Length = 360 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 34/121 (28%), Positives = 51/121 (42%), Gaps = 5/121 (4%) Query: 25 QDEVRVKIASSGLCGSDLP-RIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVAC 83 +++V+ K+ G C DL K G YP +GHE G + +GS V GD V Sbjct: 39 ENDVQFKVLYCGTCNYDLEMSTNKFGMTKYPFVIGHEIVGVVTEIGSKVQKFKVGDKVGV 98 Query: 84 VPLL-PCFTCPECLKGFYSQCAKYDFIG---SRRDGGFAEYIVVKRKNVFALPTDMPIED 139 + C C C+ G + C+K + GG +VV K P ++P+ Sbjct: 99 GGFVGACEKCEMCVNGVENNCSKVESTDGHFGNNFGGCCNIMVVNEKYAVVWPENLPLHS 158 Query: 140 G 140 G Sbjct: 159 G 159 >4J6F-A nrPDB Length = 382 Score = 52.0 bits (123), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 79/311 (25%), Positives = 123/311 (39%), Gaps = 52/311 (16%) Query: 53 YPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSR 112 +P G + G+I AVG GVD G+ V + + A D++G Sbjct: 106 FPRIQGTDTVGHIVAVGEGVDRARIGERVMVD--FSIYNRDD------DSLADIDYMGHG 157 Query: 113 RDGGFAEYIVVKRKNVFALPTDMP-IEDGAFIEPITVGLHAFHLAQGCENKNVIIIGA-G 170 RDGG+AEY+ + +N + TD+ IE F G A+ + V++ GA G Sbjct: 158 RDGGYAEYMALPAENAHVVATDLTDIELATFCCAYLTGERMLERARLAAGETVLVTGASG 217 Query: 171 TIGLLAIQCAVALGA---------KSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQ 221 +G IQ A A GA K +DI ++ + + ++ P Sbjct: 218 GVGSAIIQLARARGAVPIAVAGPGKEAAMLDIGAQAVVTRGQGDLAEAVEAASGGRP--I 275 Query: 222 SVLREL----RFNQL--ILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGK 275 V+ +L FN L IL G T A IAGP QL L + ++L Sbjct: 276 DVVADLVGGPLFNDLLKILRPEGRYTT---AGAIAGPVVQLDL-----RTMYL------- 320 Query: 276 ILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIAR 335 K+L + G SS ++ R + E+K + PL+ F +A D Sbjct: 321 ---KQLELHG-----SSQGSRADFRRLVRYIEEKK--IRPLVGGVYPLSEFHRAQTDFMA 370 Query: 336 NAMPGKVLLIP 346 GK++++P Sbjct: 371 KNFVGKLVVVP 381 >2VCY-A nrPDB Length = 344 Score = 51.6 bits (122), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 66/274 (24%), Positives = 116/274 (42%), Gaps = 43/274 (15%) Query: 27 EVRVKIASSGLCGSDLPRIFKNGAHY--YPITLGHEFSGYIDAVGSGVDDLHPGDAVACV 84 +VRVK+ ++ + SD+ I N P G+E + AVGS V L PGD V + Sbjct: 43 DVRVKMLAAPINPSDINMIQGNYGLLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWV--I 100 Query: 85 PLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAF-- 142 P A R + F+E +++ +P+D+P++ A Sbjct: 101 P------------------ANAGLGTWRTEAVFSEEALIQ------VPSDIPLQSAATLG 136 Query: 143 IEPITVGLHAFHLAQGCENKNVIIIGAGT-IGLLAIQCAVALGAKSVTAI----DIS--S 195 + P T Q +VI + + +G IQ A ALG +++ + DI S Sbjct: 137 VNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLS 196 Query: 196 EKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQ 255 ++L KS GA E+ P+M++ +++ +L L G + EL ++A Sbjct: 197 DRL---KSLGAEHVITEEELRRPEMKNFFKDMPQPRLALNCVGGKSSTELLRQLARGGTM 253 Query: 256 LALVGTLHQDLHLTSATFGKILRKELTVIGSWMN 289 + G Q + A+ ++ K+L + G W++ Sbjct: 254 VTYGGMAKQPV---VASVSLLIFKDLKLRGFWLS 284 >5ENV-A nrPDB Length = 347 Score = 50.8 bits (120), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 60/197 (30%), Positives = 82/197 (41%), Gaps = 15/197 (7%) Query: 19 IPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITL----GHEFSGYIDAVGSGVDD 74 +P+ K +E+ + + SG+C +DL +G P+ L GHE +G + +G V Sbjct: 25 VPKPK-ANELLINVKYSGVCHTDLHAW--HGDWPLPVKLPLVGGHEGAGVVVGMGENVKG 81 Query: 75 LHPGDAVACVPLL--PCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALP 132 GD A + L C C C G S C D G DG F +Y +P Sbjct: 82 WKIGD-YAGIKWLNGSCMACEYCELGNESNCPHADLSGYTHDGSFQQYATADAVQAAHIP 140 Query: 133 --TDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIG-AGTIGLLAIQCAVALGAKSVT 189 TD+ ITV A A V I G AG +G LA+Q A A+G + V Sbjct: 141 QGTDLAQVAPILCAGITV-YKALKSANLMAGHWVAISGAAGGLGSLAVQYAKAMGYR-VL 198 Query: 190 AIDISSEKLALAKSFGA 206 ID K L +S G Sbjct: 199 GIDGGEGKEELFRSIGG 215 >6C49-A nrPDB Length = 350 Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 74/271 (27%), Positives = 113/271 (41%), Gaps = 27/271 (9%) Query: 27 EVRVKIASSGLCGSDLPRIFKNGAH--YYPITLGHEFSGYIDAVGSGVDDLHPGDAVAC- 83 +V VK+ GLC SD+ + N H YP+ GHE G I A+GS L G V Sbjct: 40 QVEVKVEYCGLCHSDI-SVLNNEWHSTVYPVVAGHEIIGRIVALGSEAKGLQIGQRVGIG 98 Query: 84 VPLLPCFTCPECLKGFYSQCAKYD---FIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDG 140 C C EC+ G C + +G GGFA+ + + LP D+ E Sbjct: 99 WTAESCQACDECIGGQQVLCTGENIATIVG--HAGGFADKVRAGWQWAIPLPEDLDPESA 156 Query: 141 AFIEPITVGLHAF-----HLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISS 195 + + G+ F H Q +V +IG G +G +AI+ A G + +TA + Sbjct: 157 GPL--LCGGITVFDPLLKHKIQA--THHVGVIGIGGLGHIAIKLLKAWGCE-ITAFSSNP 211 Query: 196 EKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQ 255 +K K+ GA NS + A + Q + +F+ L+L T V + P+ Sbjct: 212 DKTEELKAMGADHVVNSRDTEAVKAQ----KGKFD-LLLSTVNVTLNWRAFISTLAPNGS 266 Query: 256 LALVGTLHQDLHLTSATFGKILRKELTVIGS 286 L +G L + G ++ +V GS Sbjct: 267 LHFLGL---TLEPVPVSVGSLIDGAKSVTGS 294 >4JLW-A nrPDB Length = 399 Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 71/262 (27%), Positives = 107/262 (40%), Gaps = 38/262 (14%) Query: 19 IPEIKHQDE--------VRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFSGYIDAVGS 70 IP K QD V +++ S+ +CGSD + + LGHE +G + +G Sbjct: 20 IPYPKMQDPQGRQIDHGVILRVVSTNICGSDQHMVRGRTTAPEGLVLGHEITGEVVEIGR 79 Query: 71 GVDDLHPGDAVACVPLLPCFTCPECLKGFYSQC---------AKYDFIG-SRRDGGFAEY 120 GV+ + GD V+ + C C C + C Y ++ GG AEY Sbjct: 80 GVETMKIGDLVSVPFNVACGHCRTCKEQHTGVCLTVNPARAGGAYGYVDMGGWVGGQAEY 139 Query: 121 IVVKRK--NVFALPTDM----PIEDGAFIEPI-TVGLHAFHLAQGCENKNVIIIGAGTIG 173 ++V N+ LP I D + I G H A V I GAG +G Sbjct: 140 VLVPYADFNLLKLPNREAAMEKIRDLTCLSDILPTGYHGAVTAGVGPGSTVYIAGAGPVG 199 Query: 174 LLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLI 233 L A A LGA V D++ +LA AK Q F +++S ++ ++ I Sbjct: 200 LAAAASARLLGAAVVIVGDVNPTRLAHAKK----QGFEIADLS--------KDTPLHEQI 247 Query: 234 LETAGVPQTVELAVEIAGPHAQ 255 G P+ V+ AV+ G A+ Sbjct: 248 AALLGEPE-VDCAVDAVGFEAR 268 >1YB5-A nrPDB Length = 351 Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 78/302 (25%), Positives = 126/302 (41%), Gaps = 49/302 (16%) Query: 54 PITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRR 113 P T G + +G I+AVG GD V F S Sbjct: 88 PYTPGSDVAGVIEAVGDNASAFKKGDRV--------------------------FTSSTI 121 Query: 114 DGGFAEYIVVKRKNVFALPTDMPIEDGAFIE-PITVGLHAF-HLAQGCENKNVIIIGA-G 170 GG+AEY + V+ LP + + GA I P A H A ++V++ GA G Sbjct: 122 SGGYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASG 181 Query: 171 TIGLLAIQCAVALGAKSV-TAIDISSEKLALAKSFGAMQTFNSSEMS-APQMQSVLRELR 228 +GL A Q A A G K + TA +K+ L GA + FN E++ +++ + E Sbjct: 182 GVGLAACQIARAYGLKILGTAGTEEGQKIVLQN--GAHEVFNHREVNYIDKIKKYVGEKG 239 Query: 229 FNQLILETAGVPQTVELAVEIAGPHAQLALV----GTLHQDLHLTSATFGKILRKELTVI 284 + +I A V + +L++ H +V GT+ + T A KE ++I Sbjct: 240 IDIIIEMLANVNLSKDLSLL---SHGGRVIVVGSRGTIEINPRDTMA-------KESSII 289 Query: 285 GSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIAR-NAMPGKVL 343 G + S+ Q++ A + E L+P+I + E A+A +I + GK++ Sbjct: 290 GVTLFSSTKEEFQQYAAALQAGMEIGW-LKPVIGSQYPLEKVAEAHENIIHGSGATGKMI 348 Query: 344 LI 345 L+ Sbjct: 349 LL 350 >1KOL-A nrPDB Length = 398 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 57/206 (27%), Positives = 87/206 (42%), Gaps = 21/206 (10%) Query: 28 VRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLL 87 V +K+ S+ +CGSD + + LGHE +G + G V++L GD V+ + Sbjct: 36 VILKVVSTNICGSDQHMVRGRTTAQVGLVLGHEITGEVIEKGRDVENLQIGDLVSVPFNV 95 Query: 88 PCFTCPECLKGFYSQC---------AKYDFIG-SRRDGGFAEYIVVKRK--NVFALPT-D 134 C C C + C Y ++ GG AEY++V N+ LP D Sbjct: 96 ACGRCRSCKEMHTGVCLTVNPARAGGAYGYVDMGDWTGGQAEYVLVPYADFNLLKLPDRD 155 Query: 135 MPIED----GAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTA 190 +E + + G H A V + GAG +GL A A LGA V Sbjct: 156 KAMEKIRDLTCLSDILPTGYHGAVTAGVGPGSTVYVAGAGPVGLAAAASARLLGAAVVIV 215 Query: 191 IDISSEKLALAKSFGAMQTFNSSEMS 216 D++ +LA AK+ Q F +++S Sbjct: 216 GDLNPARLAHAKA----QGFEIADLS 237 >5FI5-A nrPDB Length = 357 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 34/119 (28%), Positives = 51/119 (42%), Gaps = 5/119 (4%) Query: 25 QDEVRVKIASSGLCGSDLPRIFKN--GAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVA 82 + +V++K+ G C D + KN G YP LGHE G + VGS V GD V Sbjct: 42 EHDVQLKVLYCGTCQYDR-EMSKNKFGFTSYPYVLGHEIVGEVTEVGSKVQKFKVGDKVG 100 Query: 83 CVPLL-PCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDG 140 ++ C C C + C + I S G + V+ V P ++P++ G Sbjct: 101 VASIIETCGKCEMCTNEVENYCPEAGSIDSNY-GACSNIAVINENFVIRWPENLPLDSG 158 >3TQH-A nrPDB Length = 321 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 60/229 (26%), Positives = 99/229 (43%), Gaps = 45/229 (19%) Query: 1 MKSVVNDTDG---IVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHY----- 52 MK++ D G ++++ ++ PE + ++++ +K+ ++ L D +NG+ + Sbjct: 7 MKAIQFDQFGPPKVLKLVDTPTPEYR-KNQMLIKVHAASLNPIDYKT--RNGSGFVAKKL 63 Query: 53 ---YPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFI 109 P LG++FSG + +GS V++++ GD V + P C C + CA D I Sbjct: 64 KNNLPSGLGYDFSGEVIELGSDVNNVNIGDKVMGIAGFPDHPC--CYAEYV--CASPDTI 119 Query: 110 GSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENK--NVIII 167 + + K F +P T GL A E K +V++I Sbjct: 120 IQKLE-----------KLSFLQAASLP----------TAGLTALQALNQAEVKQGDVVLI 158 Query: 168 --GAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSE 214 GAG +G LAIQ A G +T S A K+ GA Q N E Sbjct: 159 HAGAGGVGHLAIQLAKQKGTTVITT--ASKRNHAFLKALGAEQCINYHE 205 >3HZZ-A nrPDB Length = 467 Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 74/309 (23%), Positives = 114/309 (36%), Gaps = 35/309 (11%) Query: 57 LGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGG 116 +G + +G + G GV+ PGD V L P+ + + GG Sbjct: 139 IGSDLAGVVLRTGPGVNAWQPGDEVVAHCLSVELESPDGHDDTMLDPEQRIWGFETNFGG 198 Query: 117 FAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHL------AQGCENKNVIIIGA- 169 AE +VK + P + E+ A P V A+ A + NV+I GA Sbjct: 199 LAEIALVKTNQLMPKPKHLTWEEAA--APGLVNSTAYRQLVSRNGAAMKQGDNVLIWGAS 256 Query: 170 GTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSE-----MSAPQMQSVL 224 G +G A Q A+A GA + + S +K + +S GA + + Q Sbjct: 257 GGLGSYATQFALAGGANPICVVS-SPQKAEICRSMGAEAIIDRNAEGYKFWKDEHTQDPK 315 Query: 225 RELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVI 284 RF + I E G + +++ E G A V + +T+ E Sbjct: 316 EWKRFGKRIRELTG-GEDIDIVFEHPGRETFGASVYVTRKGGTITTCASTSGYMHEYDNR 374 Query: 285 GSWM-----------NYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDI 333 WM NY +E A+RL+ + K + P ++ S E QA D+ Sbjct: 375 YLWMSLKRIIGSHFANY------REAYEANRLIAKGK--IHPTLSKTYSLEETGQAAYDV 426 Query: 334 ARNAMPGKV 342 RN GKV Sbjct: 427 HRNLHQGKV 435 >2DPH-A nrPDB Length = 398 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 65/229 (28%), Positives = 92/229 (40%), Gaps = 27/229 (11%) Query: 2 KSVVNDTDGIVRVAESVIPEIKHQDE-----VRVKIASSGLCGSDLPRIFKNGAHYYPI- 55 KSVV +RV P+++H + V +K+ S+ +CGSD I++ G P Sbjct: 4 KSVVYHGTRDLRVETVPYPKLEHNNRKLEHAVILKVVSTNICGSD-QHIYR-GRFIVPKG 61 Query: 56 -TLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAK--------- 105 LGHE +G + GS V+ + GD V+ + C C C + C Sbjct: 62 HVLGHEITGEVVEKGSDVELMDIGDLVSVPFNVACGRCRNCKEARSDVCENNLVNPDADL 121 Query: 106 --YDFIGSRRDGGFAEYIVVKRKNVFALPTD------MPIEDGAFIEPI-TVGLHAFHLA 156 + F GG AEY++V + L I+D I I G H A Sbjct: 122 GAFGFDLKGWSGGQAEYVLVPYADYMLLKFGDKEQAMEKIKDLTLISDILPTGFHGCVSA 181 Query: 157 QGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFG 205 +V I GAG +G A A LGA V D + E+L L G Sbjct: 182 GVKPGSHVYIAGAGPVGRCAAAGARLLGAACVIVGDQNPERLKLLSDAG 230 >1Q1N-A nrPDB Length = 360 Score = 41.2 bits (95), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 32/127 (25%), Positives = 54/127 (42%), Gaps = 10/127 (7%) Query: 20 PEIKHQDEVRVKIASSGLCGSDLPRIFKN-GAHYYPITLGHEFSGYIDAVGSGVDD-LHP 77 P+ + ++ +KI + G+CGSD+ + G P+ +GHE G + +G + L Sbjct: 28 PKPFYDHDIDIKIEACGVCGSDIHCAAGHWGNMKMPLVVGHEIVGKVVKLGPKSNSGLKV 87 Query: 78 GDAVAC-VPLLPCFTCPECLKGFYSQCAKYDFIGSR-------RDGGFAEYIVVKRKNVF 129 G V + C C C C K+ S+ GG+A Y+ V V Sbjct: 88 GQRVGVGAQVFSCLECDRCKNDNEPYCTKFVTTYSQPYEDGYVSQGGYANYVRVHEHFVV 147 Query: 130 ALPTDMP 136 +P ++P Sbjct: 148 PIPENIP 154 >3QWB-A nrPDB Length = 334 Score = 41.2 bits (95), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 52/233 (22%), Positives = 98/233 (42%), Gaps = 52/233 (22%) Query: 11 IVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAH--YYPITLGHEFSGYIDAV 68 +++ + +P I ++E+ +K +G+ + + F+ G + P LG E SG + A Sbjct: 22 VIKYEDYPVPSI-SEEELLIKNKYTGV--NYIESYFRKGIYPCEKPYVLGREASGTVVAK 78 Query: 69 GSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKN- 127 G GV + GD VA + + FA+Y + + Sbjct: 79 GKGVTNFEVGDQVAYI----------------------------SNSTFAQYSKISSQGP 110 Query: 128 VFALPTDMPIEDGAF--------IEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQC 179 V LP E+ + ++ A+H+ +G + ++ AG +GL+ Q Sbjct: 111 VMKLPKGTSDEELKLYAAGLLQVLTALSFTNEAYHVKKG--DYVLLFAAAGGVGLILNQL 168 Query: 180 AVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRE-LRFNQ 231 GA ++ A+ + EKL +AK +GA N+S+ + +LR+ L+F Sbjct: 169 LKMKGAHTI-AVASTDEKLKIAKEYGAEYLINASK------EDILRQVLKFTN 214 >2VN8-A nrPDB Length = 375 Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust. Identities = 59/245 (24%), Positives = 91/245 (37%), Gaps = 54/245 (22%) Query: 18 VIPEIKHQDEVRVKIASSGLCGSDL----------------PRIFKNGAHYYPITLGHEF 61 ++P I + +EV VK+ ++ + D+ P K +P+TLG + Sbjct: 43 MMPIIHYPNEVIVKVHAASVNPIDVNMRSGYGATALNMKRDPLHVKIKGEEFPLTLGRDV 102 Query: 62 SGYIDAVGSGVDDLHPGDAV-ACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEY 120 SG + G V PGD V A VP + G +E+ Sbjct: 103 SGVVMECGLDVKYFKPGDEVWAAVP-------------------------PWKQGTLSEF 137 Query: 121 IVVKRKNVFALPTDMPIEDGAFIEPITV-GLHAFHLAQG-----CENKNVIIIGA-GTIG 173 +VV V P + A + + + A + G C K V+I+GA G +G Sbjct: 138 VVVSGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVG 197 Query: 174 LLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLI 233 AIQ A A VTA+ S + L + GA + S + L+ F I Sbjct: 198 TFAIQVMKAWDAH-VTAV-CSQDASELVRKLGADDVIDYKSGSVEEQLKSLKPFDF---I 252 Query: 234 LETAG 238 L+ G Sbjct: 253 LDNVG 257 >4IDE-A nrPDB Length = 332 Score = 38.5 bits (88), Expect = 0.005, Method: Compositional matrix adjust. Identities = 51/207 (24%), Positives = 81/207 (39%), Gaps = 29/207 (14%) Query: 8 TDGIVRVAESV-IPEIKHQDEVRVKIASSGLCGSDLPR---IFKNGAHYYPITLGHEFSG 63 T +++ SV +PEIK +D+V +K+ ++ L D R FK+ P G++ +G Sbjct: 35 TSDVLKFDPSVAVPEIK-EDQVLIKVVAASLNPVDFKRALGYFKDTDSPLPTIPGYDVAG 93 Query: 64 YIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVV 123 + VGS V GD V Y + + R G AEY Sbjct: 94 VVVKVGSQVTKFKVGDEV------------------YGDLNETALVNPTRFGSLAEYTAA 135 Query: 124 KRKNVFALPTDMPIEDGA----FIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQC 179 + + P ++ + A IE GL L+ G + G + IQ Sbjct: 136 DERVLAHKPKNLSFIEAASLPLAIETAHEGLERAELSAGKSVLVLGGAGGVGTHI--IQL 193 Query: 180 AVALGAKSVTAIDISSEKLALAKSFGA 206 A + S A S++KL L ++ GA Sbjct: 194 AKHVFGASKVAATASTKKLDLLRTLGA 220 >3FBG-A nrPDB Length = 346 Score = 37.7 bits (86), Expect = 0.007, Method: Compositional matrix adjust. Identities = 64/264 (24%), Positives = 105/264 (39%), Gaps = 44/264 (16%) Query: 19 IPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPG 78 IPE K E+ VKI S + D + + + P LG + G +++VG+ V + G Sbjct: 27 IPEPKVH-EILVKIQSISVNPVDTKQRLMDVSKA-PRVLGFDAIGVVESVGNEVTMFNQG 84 Query: 79 DAVACVPLLPCFTCPECLKGFYSQCAKYDFIGS-RRDGGFAEYIVVKRKNVFALPTDMPI 137 D V +YS GS ++G AEY ++ + V P ++ Sbjct: 85 DIV-----------------YYS--------GSPDQNGSNAEYQLINERLVAKAPKNISA 119 Query: 138 EDGAFIEPITVGLHA----FHLAQGCENKN-------VIIIGAGTIGLLAIQCAVALGAK 186 E + P+T G+ A F + N+N +II GAG +G +A Q A A G + Sbjct: 120 EQAVSL-PLT-GITAYETLFDVFGISRNRNENEGKTLLIINGAGGVGSIATQIAKAYGLR 177 Query: 187 SVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELA 246 +T +E + K GA N E Q ++ EL + T + Sbjct: 178 VITTAS-RNETIEWTKKMGADIVLNHKESLLNQFKTQGIELV--DYVFCTFNTDMYYDDM 234 Query: 247 VEIAGPHAQLALVGTLHQDLHLTS 270 +++ P +A + D L + Sbjct: 235 IQLVKPRGHIATIVAFENDQDLNA 258 >4RVS-A nrPDB Length = 329 Score = 37.7 bits (86), Expect = 0.008, Method: Compositional matrix adjust. Identities = 55/229 (24%), Positives = 95/229 (41%), Gaps = 45/229 (19%) Query: 10 GIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAH--YYPITLGHEFSGYIDA 67 G++R + P+ H E+ +K + G+ D F++G + P +G E G ++A Sbjct: 14 GVLRHVDQPQPQPGH-GELLIKAEAIGVNFIDT--YFRSGQYPRELPFVIGSEVCGTVEA 70 Query: 68 VGSGVDD----LHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVV 123 VG GV + GD V + + +G +AE+ Sbjct: 71 VGPGVTAADTAISVGDRV---------------------------VSASANGAYAEFCTA 103 Query: 124 KRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGC---ENKNVIII--GAGTIGLLAIQ 178 +P D+ E A + GL A +L + + + +++ GAG +GL+ Q Sbjct: 104 PASLTAKVPDDVTSEVAA--SALLKGLTAHYLLKSVYPVKRGDTVLVHAGAGGVGLILTQ 161 Query: 179 CAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLREL 227 A LG + +T + ++EK L+K GA + E A Q +REL Sbjct: 162 WATHLGVRVITTVS-TAEKAKLSKDAGADVVLDYPE-DAWQFAGRVREL 208 >4A10-A nrPDB Length = 447 Score = 37.4 bits (85), Expect = 0.010, Method: Compositional matrix adjust. Identities = 53/195 (27%), Positives = 80/195 (41%), Gaps = 16/195 (8%) Query: 57 LGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGG 116 LG + SG + G GV PGD V P P + + GG Sbjct: 113 LGSDCSGVVVRTGIGVRRWKPGDHVIVHPAHVDEQEPATHGDGMLGTEQRAWGFETNFGG 172 Query: 117 FAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHL------AQGCENKNVIIIGA- 169 AEY VV+ + P + E+ A + P+ G A+ + AQ + V+I GA Sbjct: 173 LAEYGVVRASQLLPKPAHLTWEEAA-VSPLCAGT-AYRMLVSDRGAQMKQGDIVLIWGAS 230 Query: 170 GTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMS-----APQMQSVL 224 G +G AIQ V G A+ S++K A ++ G N +E+ A + V+ Sbjct: 231 GGLGSYAIQF-VKNGGGIPVAVVSSAQKEAAVRALGCDLVINRAELGITDDIADDPRRVV 289 Query: 225 RELR-FNQLILETAG 238 R +L++E AG Sbjct: 290 ETGRKLAKLVVEKAG 304 >1QOR-A nrPDB Length = 327 Score = 36.2 bits (82), Expect = 0.022, Method: Compositional matrix adjust. Identities = 44/168 (26%), Positives = 68/168 (40%), Gaps = 38/168 (22%) Query: 54 PITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRR 113 P LG E +G + VGSGV + GD V Y+Q A Sbjct: 58 PSGLGTEAAGIVSKVGSGVKHIKAGDRV-----------------VYAQSAL-------- 92 Query: 114 DGGFAEYIVVKRKNVFALPTDMPIEDGA--FIEPITVGLHAFHLAQGC-----ENKNVII 166 G ++ + LP + E A F++ +TV ++L + + + + Sbjct: 93 -GAYSSVHNIIADKAAILPAAISFEQAAASFLKGLTV----YYLLRKTYEIKPDEQFLFH 147 Query: 167 IGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSE 214 AG +GL+A Q A ALGAK + + +++K A GA Q N E Sbjct: 148 AAAGGVGLIACQWAKALGAKLIGTVG-TAQKAQSALKAGAWQVINYRE 194 >1WLY-A nrPDB Length = 333 Score = 35.8 bits (81), Expect = 0.030, Method: Compositional matrix adjust. Identities = 43/180 (23%), Positives = 70/180 (38%), Gaps = 37/180 (20%) Query: 54 PITLGHEFSGYIDAVGSGVDDLHPGDAV-ACVPLLPCFTCPECLKGFYSQCAKYDFIGSR 112 PI +G E + ++ VG GV D G+ V C+P L G YSQ Y Sbjct: 61 PIVVGFEAAAVVEEVGPGVTDFTVGERVCTCLPPL----------GAYSQERLY------ 104 Query: 113 RDGGFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHA---FHLAQGCENKNVIII-- 167 + + +P D+ ++D + G+ A H + + ++I Sbjct: 105 -----------PAEKLIKVPKDLDLDDVHLAGLMLKGMTAQYLLHQTHKVKPGDYVLIHA 153 Query: 168 GAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLREL 227 AG +G + + A LGA + + + EK A+ G T N S V+RE+ Sbjct: 154 AAGGMGHIMVPWARHLGATVIGTVS-TEEKAETARKLGCHHTINYSTQ---DFAEVVREI 209 >3B70-A nrPDB Length = 371 Score = 35.4 bits (80), Expect = 0.036, Method: Compositional matrix adjust. Identities = 77/376 (20%), Positives = 134/376 (35%), Gaps = 67/376 (17%) Query: 4 VVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPIT-LGHEFS 62 VND D + + P + +D+V V++ + + SD G P LG +++ Sbjct: 16 TVNDHDEVTVWNAAPCPMLP-RDQVYVRVEAVAINPSD---TKMRGQFATPWAFLGTDYA 71 Query: 63 GYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIV 122 G + AVGS V + GD V C P+ G F++Y V Sbjct: 72 GTVVAVGSDVTHIQVGDRVYGAQNEMCPRTPD-------------------QGAFSQYTV 112 Query: 123 VKRKNVFALPTDMPIEDGAFIEP--ITVGLHAFHLAQGCENKNV-----------IIIGA 169 + + +P + E A + T GL L + + +++ Sbjct: 113 TRGRVWAKIPKGLSFEQAAALPAGISTAGLAMKLLGLPLPSPSADQPPTHSKPVYVLVYG 172 Query: 170 GTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRF 229 G+ + + + + S LAKS GA + F + AP + +R Sbjct: 173 GSTATATVTMQMLRLSGYIPIATCSPHNFDLAKSRGAEEVF---DYRAPNLAQTIRTYTK 229 Query: 230 NQLILETAGVPQTVE------LAVEIAGPHAQLALVGTLH---QDLHLTSATFGKILRKE 280 N L + VE A+ AG H H + + T T G Sbjct: 230 NNLRYALDCI-TNVESTTFCFAAIGRAGGHYVSLNPFPEHAATRKMVTTDWTLGP----- 283 Query: 281 LTVIGSWMNYSSPW--PGQE---------WETASRLLTERKLSLEPLIAHRGSFESFAQA 329 T+ G + +P+ PG E W A +L+ + +L PL +G F+ Q Sbjct: 284 -TIFGEGSTWPAPYGRPGSEEERQFGEDLWRIAGQLVEDGRLVHHPLRVVQGGFDHIKQG 342 Query: 330 VRDIARNAMPGKVLLI 345 + + + + G+ L++ Sbjct: 343 MELVRKGELSGEKLVV 358 >2VHY-A nrPDB Length = 377 Score = 34.3 bits (77), Expect = 0.073, Method: Compositional matrix adjust. Identities = 19/41 (46%), Positives = 28/41 (68%), Gaps = 1/41 (2%) Query: 158 GCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKL 198 G E +V++IGAGT G A + A +GA +VT +DI+ +KL Sbjct: 165 GVEPADVVVIGAGTAGYNAARIANGMGA-TVTVLDINIDKL 204 >4TXK-A nrPDB Length = 615 Score = 33.9 bits (76), Expect = 0.100, Method: Compositional matrix adjust. Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 10/98 (10%) Query: 92 CPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRK-NVFALPTDMPIEDGAFIEPITVGL 150 C + L F C +G GG ++Y +K + N ++ + D +P+ Sbjct: 23 CQDVLSSFQGLCRA---LGVESGGGLSQYHKIKAQLNYWSAKSLWAKLDKRASQPV---- 75 Query: 151 HAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSV 188 + Q C N +++GAG GL A LGA+ V Sbjct: 76 --YQQGQACTNTKCLVVGAGPCGLRAAVELALLGARVV 111 >2BRY-A nrPDB Length = 497 Score = 33.5 bits (75), Expect = 0.14, Method: Compositional matrix adjust. Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 10/98 (10%) Query: 92 CPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRK-NVFALPTDMPIEDGAFIEPITVGL 150 C + L F C +G GG ++Y +K + N ++ + D +P+ Sbjct: 31 CQDVLSSFQGLCRA---LGVESGGGLSQYHKIKAQLNYWSAKSLWAKLDKRASQPV---- 83 Query: 151 HAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSV 188 + Q C N +++GAG GL A LGA+ V Sbjct: 84 --YQQGQACTNTKCLVVGAGPCGLRAAVELALLGARVV 119 >4DZR-A nrPDB Length = 215 Score = 32.7 bits (73), Expect = 0.21, Method: Compositional matrix adjust. Identities = 20/56 (35%), Positives = 35/56 (62%), Gaps = 5/56 (8%) Query: 163 NVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAK----SFGAMQTFNSSE 214 VI +G G+ G +A+ A+A SVTA+D+S + LA+A+ FGA+ + +++ Sbjct: 33 RVIDVGTGS-GCIAVSIALACPGVSVTAVDLSMDALAVARRNAERFGAVVDWAAAD 87 >3KD3-A nrPDB Length = 219 Score = 32.3 bits (72), Expect = 0.34, Method: Compositional matrix adjust. Identities = 22/60 (36%), Positives = 32/60 (53%), Gaps = 7/60 (11%) Query: 117 FAEYIVVKRKNVFALPTDMPIEDGAFIE------PITVGLHAFHLAQGCENKNVIIIGAG 170 FA+Y+ + R+N+FA+ T + DG+F E L AF A+G + VI IG G Sbjct: 115 FADYLNIPRENIFAVET-IWNSDGSFKELDNSNGACDSKLSAFDKAKGLIDGEVIAIGDG 173 >4ADL-A nrPDB Length = 495 Score = 32.0 bits (71), Expect = 0.37, Method: Compositional matrix adjust. Identities = 14/34 (41%), Positives = 21/34 (61%), Gaps = 5/34 (14%) Query: 54 PITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLL 87 P+TLG EFSGY + +G++ + AC+P L Sbjct: 215 PVTLGQEFSGYARQIEAGIERVR-----ACLPRL 243 >2EEZ-A nrPDB Length = 369 Score = 31.6 bits (70), Expect = 0.57, Method: Compositional matrix adjust. Identities = 15/41 (36%), Positives = 28/41 (68%), Gaps = 1/41 (2%) Query: 158 GCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKL 198 G +V+I+G GT+G A + A+ +GA+ VT +D++ ++L Sbjct: 163 GVAPASVVILGGGTVGTNAAKIALGMGAQ-VTILDVNHKRL 202 >1SN7-A nrPDB Length = 364 Score = 31.2 bits (69), Expect = 0.66, Method: Compositional matrix adjust. Identities = 28/94 (29%), Positives = 42/94 (44%), Gaps = 8/94 (8%) Query: 208 QTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAG---PHAQLALVGTLHQ 264 Q F S + APQ+ SV + NQ + +G VEL +E+AG P A+ A+ + Sbjct: 44 QYFASLGVPAPQVVSVSVDGASNQPTGDPSGPDGEVELDIEVAGALAPGAKFAVYFAPNT 103 Query: 265 DL----HLTSATFGKILRKELTVIGSWMNYSSPW 294 D +T+A L+ + I SW W Sbjct: 104 DAGFLDAITTAIHDPTLKPSVVSI-SWGGPEDSW 136 >1NHQ-A nrPDB Length = 447 Score = 31.2 bits (69), Expect = 0.78, Method: Compositional matrix adjust. Identities = 25/60 (41%), Positives = 31/60 (51%), Gaps = 6/60 (10%) Query: 160 ENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLA--LAKSFGAMQTFNSSEMSA 217 E NV++IG+G IG+ A + A A K VT IDI L L K F + T EM A Sbjct: 148 EVNNVVVIGSGYIGIEAAE-AFAKAGKKVTVIDILDRPLGVYLDKEFTDVLT---EEMEA 203 >2CF5-A nrPDB Length = 357 Score = 30.8 bits (68), Expect = 0.79, Method: Compositional matrix adjust. Identities = 68/258 (26%), Positives = 110/258 (42%), Gaps = 20/258 (7%) Query: 26 DEVRVKIASSGLCGSDLPRIFKN-GAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACV 84 ++V ++I G+C +DL + + G YP+ GHE G + VGS V GD V Sbjct: 35 EDVNIRIICCGICHTDLHQTKNDLGMSNYPMVPGHEVVGEVVEVGSDVSKFTVGDIVGVG 94 Query: 85 PLL-------PCFTCPE--CLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDM 135 L+ PC E C K +S Y G GGFA+ VV +K V +P M Sbjct: 95 CLVGCCGGCSPCERDLEQYCPKKIWSYNDVY-INGQPTQGGFAKATVVHQKFVVKIPEGM 153 Query: 136 PIEDGA--FIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDI 193 +E A +TV H I+G G +G + ++ A A+G VT I Sbjct: 154 AVEQAAPLLCAGVTVYSPLSHFGLKQPGLRGGILGLGGVGHMGVKIAKAMG-HHVTVISS 212 Query: 194 SSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFN-QLILETAGVPQTVELAVEIAGP 252 S++K A+Q + + Q+ + EL + +++T V +E + + Sbjct: 213 SNKKRE-----EALQDLGADDYVIGSDQAKMSELADSLDYVIDTVPVHHALEPYLSLLKL 267 Query: 253 HAQLALVGTLHQDLHLTS 270 +L L+G ++ L + Sbjct: 268 DGKLILMGVINNPLQFLT 285 >1YFM-A nrPDB Length = 488 Score = 30.8 bits (68), Expect = 0.98, Method: Compositional matrix adjust. Identities = 11/19 (57%), Positives = 15/19 (78%) Query: 54 PITLGHEFSGYIDAVGSGV 72 P+TLG EFSGY+ V +G+ Sbjct: 219 PLTLGQEFSGYVQQVENGI 237 >3VH2-A nrPDB Length = 616 Score = 30.8 bits (68), Expect = 0.99, Method: Compositional matrix adjust. Identities = 11/33 (33%), Positives = 21/33 (63%) Query: 160 ENKNVIIIGAGTIGLLAIQCAVALGAKSVTAID 192 +N V+++GAGT+G + +A G + +T +D Sbjct: 326 KNTKVLLLGAGTLGCYVSRALIAWGVRKITFVD 358 >1T1I-A nrPDB Length = 364 Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust. Identities = 31/107 (28%), Positives = 47/107 (43%), Gaps = 5/107 (4%) Query: 208 QTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAG---PHAQLALVGTLHQ 264 Q F S +SAPQ+ SV + NQ + G VEL +E+AG P A++A+ + Sbjct: 44 QYFASLGVSAPQVVSVSVDGATNQPTGDPNGPDGEVELDIEVAGALAPGAKIAVYFAPNT 103 Query: 265 DLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKL 311 D +A + + T S ++ S+ P W AS R Sbjct: 104 DAGFLNAITTAV--HDPTHKPSIVSISAGGPEDSWAPASIAAMNRAF 148 >3T7E-A nrPDB Length = 344 Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust. Identities = 11/33 (33%), Positives = 21/33 (63%) Query: 160 ENKNVIIIGAGTIGLLAIQCAVALGAKSVTAID 192 +N V+++GAGT+G + +A G + +T +D Sbjct: 37 KNTKVLLLGAGTLGCYVSRALIAWGVRKITFVD 69 >3SLK-A nrPDB Length = 795 Score = 30.0 bits (66), Expect = 1.5, Method: Compositional matrix adjust. Identities = 51/212 (24%), Positives = 84/212 (39%), Gaps = 39/212 (18%) Query: 9 DGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFSGYIDAV 68 DG+ V E EVR+ + ++G+ D + G + +LG E +G + Sbjct: 222 DGLALVDEPTATAPLGDGEVRIAMRAAGVNFRDA--LIALGMYPGVASLGSEGAGVVVET 279 Query: 69 GSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNV 128 G GV L PGD V + ++P K F + +R G++ Sbjct: 280 GPGVTGLAPGDRV--MGMIP--------KAFGPLAVADHRMVTRIPAGWS---------- 319 Query: 129 FALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIII--GAGTIGLLAIQCAVALGAK 186 FA +PI F+ +A G +++ AG +G+ AIQ A LGA+ Sbjct: 320 FARAASVPI---VFL----TAYYALVDLAGLRPGESLLVHSAAGGVGMAAIQLARHLGAE 372 Query: 187 --------SVTAIDISSEKLALAKSFGAMQTF 210 A+++S E LA +++ Q F Sbjct: 373 VYATASEDKWQAVELSREHLASSRTCDFEQQF 404 >1XLT-A nrPDB Length = 384 Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust. Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 19/96 (19%) Query: 163 NVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFG---------AMQTFNSS 213 V++ G G GL AI A LGA V A D+ + +S G AM+T ++ Sbjct: 174 RVLVFGVGVAGLQAIATAKRLGA-VVMATDVRAATKEQVESLGGKFITVDDEAMKTAETA 232 Query: 214 ---------EMSAPQMQSVLRELRFNQLILETAGVP 240 E Q ++VL+EL + + TA +P Sbjct: 233 GGYAKEMGEEFRKKQAEAVLKELVKTDIAITTALIP 268 >1T1E-A nrPDB Length = 552 Score = 29.6 bits (65), Expect = 2.1, Method: Compositional matrix adjust. Identities = 28/94 (29%), Positives = 42/94 (44%), Gaps = 8/94 (8%) Query: 208 QTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAG---PHAQLALVGTLHQ 264 Q F S +SAPQ+ SV + NQ + G VEL +E+AG P A++A+ + Sbjct: 232 QYFASLGVSAPQVVSVSVDGATNQPTGDPNGPDGEVELDIEVAGALAPGAKIAVYFAPNT 291 Query: 265 DL----HLTSATFGKILRKELTVIGSWMNYSSPW 294 D +T+A + + I SW W Sbjct: 292 DAGFLNAITTAVHDPTHKPSIVSI-SWGGPEDSW 324 >2YFH-A nrPDB Length = 448 Score = 29.3 bits (64), Expect = 2.5, Method: Compositional matrix adjust. Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 1/80 (1%) Query: 115 GGFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGL 174 GGF ++ + F P G + T + H G E V + G+G + Sbjct: 186 GGFYNGVLTGKARSFGGSLIRPEATGYGLVYFTEAMLKRH-GMGFEGMRVSVSGSGNVAQ 244 Query: 175 LAIQCAVALGAKSVTAIDIS 194 AI+ A+ GA+ +TA D S Sbjct: 245 YAIEKAMEFGARVITASDSS 264 >3QBP-A nrPDB Length = 478 Score = 28.9 bits (63), Expect = 3.3, Method: Compositional matrix adjust. Identities = 10/20 (50%), Positives = 15/20 (75%) Query: 54 PITLGHEFSGYIDAVGSGVD 73 P+TLG EFSGY + +G++ Sbjct: 202 PVTLGQEFSGYARQIEAGIE 221 >4FHN-X nrPDB Length = 450 Score = 28.9 bits (63), Expect = 3.5, Method: Compositional matrix adjust. Identities = 18/63 (28%), Positives = 28/63 (44%), Gaps = 8/63 (12%) Query: 140 GAFIEPITVGLHAFHLAQ--------GCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAI 191 G+ I P G + + G E V + G+G + AI+ A+ GA+ +TA Sbjct: 206 GSLIRPEATGYGLVYFTEAMLKRHGMGFEGMRVSVSGSGNVAQYAIEKAMEFGARVITAS 265 Query: 192 DIS 194 D S Sbjct: 266 DSS 268 >1X14-A nrPDB Length = 401 Score = 28.9 bits (63), Expect = 3.8, Method: Compositional matrix adjust. Identities = 20/44 (45%), Positives = 24/44 (54%), Gaps = 1/44 (2%) Query: 163 NVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGA 206 V++IGAG GL AI A +LGA V A D E +S GA Sbjct: 174 KVMVIGAGVAGLAAIGAANSLGA-IVRAFDTRPEVKEQVQSMGA 216 >3TV2-A nrPDB Length = 459 Score = 28.5 bits (62), Expect = 4.8, Method: Compositional matrix adjust. Identities = 10/19 (52%), Positives = 14/19 (73%) Query: 54 PITLGHEFSGYIDAVGSGV 72 P+TLG EFSGY+ + G+ Sbjct: 190 PLTLGQEFSGYVAQLDQGI 208 >4EYE-A nrPDB Length = 342 Score = 28.1 bits (61), Expect = 5.2, Method: Compositional matrix adjust. Identities = 70/331 (21%), Positives = 128/331 (38%), Gaps = 51/331 (15%) Query: 28 VRVKIASSGLCGSDLPRIFKNGAHYY-----PITLGHEFSGYIDAVGSGVDDLHPGDAVA 82 V V + ++G+C P Y P G E +G + + G + PGD V Sbjct: 51 VVVDVKAAGVC---FPDYLMTKGEYQLKMEPPFVPGIETAGVVRSAPEG-SGIKPGDRVM 106 Query: 83 CVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAF 142 ++FIG G+AE + V N+ LPT ++D Sbjct: 107 A----------------------FNFIG-----GYAERVAVAPSNI--LPTPPQLDDAEA 137 Query: 143 IEPITVGLHAFHLAQGCENK------NVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSE 196 + + H + A + +++ AG IG AIQ A +GAK + ++ ++ Sbjct: 138 VA-LIANYHTMYFAYARRGQLRAGETVLVLGAAGGIGTAAIQIAKGMGAKVIAVVNRTAA 196 Query: 197 KLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQL 256 KS GA E A ++ + ++++ G P + AV +L Sbjct: 197 T-EFVKSVGADIVLPLEEGWAKAVREATGGAGVD-MVVDPIGGP-AFDDAVRTLASEGRL 253 Query: 257 ALVGTLHQDLHLTSATFGKILRKELTVIG-SWMNYSSPWPGQEWETASRLLTERKLSLEP 315 +VG + + ++L + ++IG +W + +ET + L + P Sbjct: 254 LVVGFAAG--GIPTIKVNRLLLRNASLIGVAWGEFLRTHADYLYETQAGLEKLVAEGMRP 311 Query: 316 LIAHRGSFESFAQAVRDIARNAMPGKVLLIP 346 ++ R QA++D A + GK++L+P Sbjct: 312 PVSARIPLSEGRQALQDFADGKVYGKMVLVP 342 >4HGV-A nrPDB Length = 495 Score = 27.7 bits (60), Expect = 8.5, Method: Compositional matrix adjust. Identities = 22/67 (32%), Positives = 29/67 (43%), Gaps = 16/67 (23%) Query: 13 RVAESVIPEIKHQD---EVRVKIASSGLCGSDLPRIFKNGAHYY----PITLGHEFSGYI 65 RV ++P +KH E +VK I K G + P+TLG EFSGY Sbjct: 187 RVIHDLLPALKHLHKALEEKVKA---------FDHIIKIGRTHTQDATPLTLGQEFSGYA 237 Query: 66 DAVGSGV 72 V S + Sbjct: 238 AQVASSI 244 >2Z7X-A nrPDB Length = 549 Score = 27.3 bits (59), Expect = 9.8, Method: Compositional matrix adjust. Identities = 14/61 (22%), Positives = 32/61 (52%) Query: 191 IDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIA 250 +D++S L + TF+ SE+S + S++++ F + + + Q ++L +I+ Sbjct: 192 VDVTSSVECLELRDTDLDTFHFSELSTGETNSLIKKFTFRNVKITDESLFQVMKLLNQIS 251 Query: 251 G 251 G Sbjct: 252 G 252 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4UEJ-A nrPDB 415 e-116 2DFV-A nrPDB 318 2e-87 3GFB-A nrPDB 316 1e-86 1PL8-A nrPDB 303 8e-83 3QE3-A nrPDB 302 2e-82 2EER-A nrPDB 290 5e-79 4EJ6-A nrPDB 286 1e-77 1E3J-A nrPDB 284 2e-77 2DQ4-A nrPDB 284 4e-77 5VM2-A nrPDB 283 1e-76 3PII-A nrPDB 278 2e-75 5KIA-A nrPDB 276 1e-74 1HSO-A nrPDB 275 2e-74 3COS-A nrPDB 272 1e-73 1HSZ-A nrPDB 271 2e-73 1U3W-A nrPDB 270 5e-73 3MEQ-A nrPDB 268 2e-72 4CPD-A nrPDB 268 2e-72 4ILK-A nrPDB 267 4e-72 1LLU-A nrPDB 266 8e-72 4RQU-A nrPDB 265 2e-71 1EE2-A nrPDB 264 4e-71 1R37-A nrPDB 263 1e-70 4Z6K-A nrPDB 262 1e-70 3S2F-A nrPDB 260 5e-70 1E3E-A nrPDB 258 2e-69 1H2B-A nrPDB 258 3e-69 1D1T-A nrPDB 257 6e-69 5YLN-A nrPDB 254 3e-68 1MC5-A nrPDB 254 3e-68 4OH1-A nrPDB 254 5e-68 4EEZ-A nrPDB 250 6e-67 6N7L-A nrPDB 248 2e-66 1CDO-A nrPDB 245 2e-65 6DKH-A nrPDB 244 3e-65 3IP1-A nrPDB 244 5e-65 5K1S-A nrPDB 243 1e-64 4DLA-A nrPDB 242 1e-64 3M6I-A nrPDB 242 2e-64 4JJI-A nrPDB 241 3e-64 1F8F-A nrPDB 239 2e-63 1YKF-A nrPDB 235 3e-62 1P0F-A nrPDB 234 3e-62 3FPC-A nrPDB 234 6e-62 3FPL-A nrPDB 232 2e-61 3FSR-A nrPDB 232 2e-61 1KEV-A nrPDB 229 1e-60 2OUI-A nrPDB 229 1e-60 5TNX-A nrPDB 226 1e-59 4GKV-A nrPDB 220 8e-58 6FG0-A nrPDB 218 2e-57 2H6E-A nrPDB 217 4e-57 3WLE-A nrPDB 216 2e-56 5ENV-A nrPDB 211 4e-55 5YAT-A nrPDB 211 4e-55 3UOG-A nrPDB 207 7e-54 3TWO-A nrPDB 206 9e-54 1YQX-A nrPDB 192 1e-49 3HZZ-A nrPDB 189 1e-48 4J6F-A nrPDB 189 2e-48 1UUF-A nrPDB 187 7e-48 5Z0C-A nrPDB 185 3e-47 1YB5-A nrPDB 182 2e-46 5VKT-A nrPDB 177 5e-45 6C49-A nrPDB 175 2e-44 5FI5-A nrPDB 175 2e-44 1Q1N-A nrPDB 170 7e-43 5H82-A nrPDB 168 3e-42 2DPH-A nrPDB 168 3e-42 2VCY-A nrPDB 166 1e-41 4OAQ-A nrPDB 166 1e-41 3QWB-A nrPDB 164 5e-41 5H83-A nrPDB 162 2e-40 4JLW-A nrPDB 162 2e-40 1KOL-A nrPDB 158 3e-39 3TQH-A nrPDB 158 3e-39 Sequences not found previously or not previously below threshold: 3JYN-A nrPDB 153 1e-37 4RVS-A nrPDB 150 9e-37 2OBY-A nrPDB 143 1e-34 4A10-A nrPDB 142 2e-34 1WLY-A nrPDB 134 5e-32 1QOR-A nrPDB 130 8e-31 2VN8-A nrPDB 130 1e-30 4EYE-A nrPDB 125 2e-29 4IDE-A nrPDB 125 2e-29 3FBG-A nrPDB 125 2e-29 4Y1B-A nrPDB 123 8e-29 2CF5-A nrPDB 122 2e-28 4DVJ-A nrPDB 119 2e-27 4A27-A nrPDB 118 3e-27 5A3V-A nrPDB 109 2e-24 2WEK-A nrPDB 109 2e-24 3B70-A nrPDB 108 4e-24 3SLK-A nrPDB 106 2e-23 2VWH-A nrPDB 103 1e-22 5LB9-A nrPDB 96 2e-20 2CDC-A nrPDB 90 1e-18 1V3V-A nrPDB 87 8e-18 1O89-A nrPDB 85 3e-17 5GXF-A nrPDB 75 5e-14 3WID-A nrPDB 74 8e-14 2Y05-A nrPDB 72 3e-13 2J3K-A nrPDB 72 5e-13 2ZB3-A nrPDB 58 6e-09 2VNA-A nrPDB 57 1e-08 3MGG-A nrPDB 41 6e-04 1X14-A nrPDB 40 0.001 1XLT-A nrPDB 39 0.003 2BRY-A nrPDB 39 0.004 4TXK-A nrPDB 38 0.004 2EGU-A nrPDB 37 0.011 4DIO-A nrPDB 37 0.012 4XIJ-A nrPDB 37 0.014 1ZCJ-A nrPDB 37 0.016 1CYD-A nrPDB 37 0.019 5F8E-A nrPDB 36 0.020 1W1U-A nrPDB 36 0.020 6BII-A nrPDB 36 0.021 5UYY-A nrPDB 36 0.024 3ZWA-A nrPDB 36 0.029 3VPX-A nrPDB 36 0.029 5D84-A nrPDB 36 0.030 2E84-A nrPDB 35 0.045 5EKU-A nrPDB 35 0.047 4M36-A nrPDB 35 0.047 1BW9-B nrPDB 35 0.050 3D2L-A nrPDB 35 0.062 1XDW-A nrPDB 35 0.069 2B25-A nrPDB 34 0.076 1V9L-A nrPDB 34 0.079 5C7I-O nrPDB 34 0.086 4N7R-A nrPDB 34 0.095 5ILO-A nrPDB 34 0.10 4FHN-X nrPDB 34 0.11 3PPI-A nrPDB 34 0.11 2VHY-A nrPDB 34 0.11 3D3W-A nrPDB 34 0.11 1GPJ-A nrPDB 34 0.12 1JWB-B nrPDB 34 0.12 3BKW-A nrPDB 34 0.12 5WQS-A nrPDB 34 0.12 2YFH-A nrPDB 33 0.13 5XW0-A nrPDB 33 0.14 1PS9-A nrPDB 33 0.16 2GPY-A nrPDB 33 0.18 1A5Z-A nrPDB 33 0.20 5Z1Z-A nrPDB 33 0.21 3V2G-A nrPDB 33 0.23 1DXY-A nrPDB 33 0.23 2HMT-A nrPDB 33 0.23 5BUT-A nrPDB 33 0.25 4X28-D nrPDB 33 0.25 4CUK-A nrPDB 33 0.26 1QO8-A nrPDB 32 0.30 2VYN-D nrPDB 32 0.35 2O23-A nrPDB 32 0.35 2A9F-A nrPDB 32 0.35 2EEZ-A nrPDB 32 0.37 1ZFN-A nrPDB 32 0.37 1CRW-G nrPDB 32 0.37 1E3W-A nrPDB 32 0.38 6CU3-A nrPDB 32 0.40 5JXW-A nrPDB 32 0.40 1JG3-A nrPDB 32 0.41 3EGI-A nrPDB 32 0.41 3GDH-A nrPDB 32 0.41 6C55-A nrPDB 32 0.42 4PZE-A nrPDB 32 0.49 2ZZN-A nrPDB 32 0.51 5JJC-A nrPDB 32 0.54 4J90-A nrPDB 32 0.55 3HM2-A nrPDB 32 0.58 5ZBK-A nrPDB 32 0.59 3HDH-A nrPDB 32 0.60 4K2X-A nrPDB 32 0.61 6J0Z-C nrPDB 31 0.63 3VH2-A nrPDB 31 0.63 3T7E-A nrPDB 31 0.63 3OND-A nrPDB 31 0.63 3G1U-A nrPDB 31 0.64 6NJP-A nrPDB 31 0.67 3KYD-B nrPDB 31 0.68 2EKL-A nrPDB 31 0.70 3KYC-B nrPDB 31 0.70 1DL5-A nrPDB 31 0.72 1VH3-A nrPDB 31 0.76 3FBT-A nrPDB 31 0.82 2OBL-A nrPDB 31 0.89 6BQ5-A nrPDB 31 0.92 5VMT-A nrPDB 31 0.95 6GBN-A nrPDB 31 0.97 1F14-A nrPDB 31 0.97 4LRT-B nrPDB 31 0.99 2LDB-A nrPDB 31 1.00 5AOV-A nrPDB 31 1.0 3GG2-A nrPDB 31 1.0 3X43-A nrPDB 30 1.1 6ARH-A nrPDB 30 1.1 3AOE-A nrPDB 30 1.2 3H9E-O nrPDB 30 1.2 4RDI-A nrPDB 30 1.3 6HNS-A nrPDB 30 1.3 6DLL-A nrPDB 30 1.3 5JE5-A nrPDB 30 1.3 6APH-A nrPDB 30 1.4 5YSS-A nrPDB 30 1.4 5BXY-A nrPDB 30 1.5 1HL3-A nrPDB 30 1.5 4DYD-A nrPDB 30 1.6 3X2F-A nrPDB 30 1.7 4XTI-A nrPDB 30 1.7 1I6N-A nrPDB 30 1.8 4K28-A nrPDB 30 1.8 1YOV-B nrPDB 30 1.8 3F9I-A nrPDB 30 1.9 2BHS-A nrPDB 30 1.9 2ZJ1-A nrPDB 30 1.9 2NVU-B nrPDB 30 2.0 4XGI-A nrPDB 30 2.2 3NJ4-A nrPDB 30 2.2 3DC2-A nrPDB 30 2.3 2AVN-A nrPDB 30 2.3 1MV8-A nrPDB 30 2.3 1LTH-T nrPDB 30 2.4 3GDF-A nrPDB 29 2.4 3JTM-A nrPDB 29 2.5 4Z87-A nrPDB 29 2.5 3H9U-A nrPDB 29 2.6 5NMX-A nrPDB 29 2.6 4E4T-A nrPDB 29 2.6 4GCM-A nrPDB 29 2.6 5IJZ-A nrPDB 29 2.6 4WJI-A nrPDB 29 2.8 5TQV-A nrPDB 29 2.8 1DOD-A nrPDB 29 2.8 2HAE-A nrPDB 29 3.3 5B37-A nrPDB 29 3.5 2AS0-A nrPDB 29 3.5 5GVX-A nrPDB 29 3.8 1WY7-A nrPDB 29 3.9 3VAZ-P nrPDB 28 4.7 3OH0-A nrPDB 28 4.7 2HQM-A nrPDB 28 4.7 2JC3-A nrPDB 28 4.8 1CP2-A nrPDB 28 4.8 2YQ5-A nrPDB 28 4.9 4YRY-B nrPDB 28 5.0 5XW3-A nrPDB 28 5.1 4P4L-A nrPDB 28 5.1 3OC4-A nrPDB 28 5.2 4PRK-A nrPDB 28 5.4 3VZS-A nrPDB 28 5.5 5FUB-A nrPDB 28 5.5 3OKC-A nrPDB 28 5.6 3FG2-P nrPDB 28 5.6 4TN1-B nrPDB 28 5.6 4NCL-A nrPDB 28 5.6 3GG9-A nrPDB 28 5.6 4N3G-A nrPDB 28 5.6 3R9U-A nrPDB 28 5.8 5HQN-A nrPDB 28 5.9 5FI9-A nrPDB 28 5.9 1L1F-A nrPDB 28 6.0 3FEO-A nrPDB 28 6.2 1O8Q-A nrPDB 28 6.2 4COO-A nrPDB 28 6.7 2WWR-A nrPDB 28 6.8 1M54-A nrPDB 28 7.0 2R9Z-A nrPDB 28 7.1 1VHC-A nrPDB 28 7.2 3AOE-E nrPDB 28 7.3 3TNL-A nrPDB 28 7.4 4IZO-A nrPDB 28 7.6 2YVG-A nrPDB 28 7.7 5MMS-A nrPDB 28 7.7 1NVM-B nrPDB 28 8.1 6ABI-A nrPDB 28 8.3 3JTJ-A nrPDB 28 8.3 6DHM-A nrPDB 28 8.4 2WUG-A nrPDB 28 8.6 5MH6-A nrPDB 28 8.8 1ZEJ-A nrPDB 28 8.9 5ZME-A nrPDB 27 9.1 4ZGS-A nrPDB 27 9.5 1B26-A nrPDB 27 9.5 1EUZ-A nrPDB 27 9.6 >4UEJ-A nrPDB Length = 346 Score = 415 bits (1068), Expect = e-116, Method: Composition-based stats. Identities = 346/346 (100%), Positives = 346/346 (100%) Query: 1 MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHE 60 MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHE Sbjct: 1 MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHE 60 Query: 61 FSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEY 120 FSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEY Sbjct: 61 FSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEY 120 Query: 121 IVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCA 180 IVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCA Sbjct: 121 IVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCA 180 Query: 181 VALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVP 240 VALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVP Sbjct: 181 VALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVP 240 Query: 241 QTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWE 300 QTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWE Sbjct: 241 QTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWE 300 Query: 301 TASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP 346 TASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP Sbjct: 301 TASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP 346 >2DFV-A nrPDB Length = 347 Score = 318 bits (815), Expect = 2e-87, Method: Composition-based stats. Identities = 99/351 (28%), Positives = 161/351 (45%), Gaps = 15/351 (4%) Query: 1 MKSVVNDTDGI-VRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRI----FKNGAHYYPI 55 M +++ G + E +P+ EV +K+ ++ +CG+DL + P Sbjct: 4 MVAIMKTKPGYGAELVEVDVPK-PGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQ 62 Query: 56 TLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDG 115 +GHE +G + +G GV+ + GD V+ + C C C +G Y C G DG Sbjct: 63 IMGHEVAGEVVEIGPGVEGIEVGDYVSVETHIVCGKCYACRRGQYHVCQNTKIFGVDTDG 122 Query: 116 GFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLL 175 FAEY VV +N++ P +P E EP+ + LA K+V+I GAG +GLL Sbjct: 123 VFAEYAVVPAQNIWKNPKSIPPEYATLQEPLGNAVDTV-LAGPISGKSVLITGAGPLGLL 181 Query: 176 AIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILE 235 I A A GA V + S + LAK GA N E + + + + LE Sbjct: 182 GIAVAKASGAYPVIVSEPSDFRRELAKKVGADYVINPFEEDVVKEVMDITDGNGVDVFLE 241 Query: 236 TAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWP 295 +G P+ +E ++ P +++L+G + + I+ K LT+ G + Sbjct: 242 FSGAPKALEQGLQAVTPAGRVSLLGLYPGKVTIDFNNL--IIFKALTIYGITGRH----L 295 Query: 296 GQEWETASRLLTERKLSLEPLIAHRGS-FESFAQAVRDIARNAMPGKVLLI 345 + W T SRLL KL+L+P+I H+ F+ + +A + R GKV+ + Sbjct: 296 WETWYTVSRLLQSGKLNLDPIITHKYKGFDKYEEAFE-LMRAGKTGKVVFM 345 >3GFB-A nrPDB Length = 350 Score = 316 bits (810), Expect = 1e-86, Method: Composition-based stats. Identities = 99/352 (28%), Positives = 160/352 (45%), Gaps = 15/352 (4%) Query: 1 MKSVVNDTDGI-VRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRI----FKNGAHYYPI 55 M++++ + E +P+ EV +K+ ++ +CG+DL + P Sbjct: 5 MQAIMKTKPAYGAELVEVDVPK-PGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQ 63 Query: 56 TLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDG 115 +GHE +G + VG GV+DL GD ++ + C C C Y C G DG Sbjct: 64 IMGHEVAGEVVEVGPGVEDLQVGDYISVETHIVCGKCYACKHNRYHVCQNTKIFGVDMDG 123 Query: 116 GFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLL 175 FA Y +V KN + P DMP E A EP+ + LA ++ +I GAG +GLL Sbjct: 124 VFAHYAIVPAKNAWKNPKDMPPEYAALQEPLGNAVDTV-LAGPIAGRSTLITGAGPLGLL 182 Query: 176 AIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILE 235 I A A GA V + S + LAK GA N E + + + ++ LE Sbjct: 183 GIAVAKASGAYPVIVSEPSEFRRKLAKKVGADYVVNPFEEDPVKFVMDITDGAGVEVFLE 242 Query: 236 TAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWP 295 +G P+ +E ++ P +++L+G +++ + I+ K L V G + Sbjct: 243 FSGAPKALEQGLKAVTPGGRVSLLGLFPREVTIDFNNL--IIFKALEVHGITGRH----L 296 Query: 296 GQEWETASRLLTERKLSLEPLIAHRGS-FESFAQAVRDIARNAMPGKVLLIP 346 + W T S L+ KL+L+P+I H+ F+ F +A + R GKV+ P Sbjct: 297 WETWYTVSSLIQSGKLNLDPIITHKYKGFDKFEEAFE-LMRAGKTGKVVFFP 347 >1PL8-A nrPDB Length = 356 Score = 303 bits (776), Expect = 8e-83, Method: Composition-based stats. Identities = 93/341 (27%), Positives = 153/341 (44%), Gaps = 17/341 (4%) Query: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIF----KNGAHYYPITLG 58 S+V G +R+ IPE +EV +++ S G+CGSD+ N P+ LG Sbjct: 10 SLVVHGPGDLRLENYPIPE-PGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLG 68 Query: 59 HEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRD-GGF 117 HE SG ++ VGS V L PGD VA P P C G Y+ F + D G Sbjct: 69 HEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNL 128 Query: 118 AEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAI 177 + + LP ++ E+GA IEP++VG+HA V++ GAG IG++ + Sbjct: 129 CRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTL 188 Query: 178 QCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRF--NQLILE 235 A A+GA V D+S+ +L+ AK GA S+ S ++ + ++ +E Sbjct: 189 LVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIE 248 Query: 236 TAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWP 295 G +++ + L LVG + +T+ +E+ + G + Y + WP Sbjct: 249 CTGAEASIQAGIYATRSGGTLVLVGLGSE---MTTVPLLHAAIREVDIKGVF-RYCNTWP 304 Query: 296 GQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARN 336 A +L + ++++PL+ HR E +A + Sbjct: 305 -----VAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKG 340 >3QE3-A nrPDB Length = 355 Score = 302 bits (773), Expect = 2e-82, Method: Composition-based stats. Identities = 99/341 (29%), Positives = 155/341 (45%), Gaps = 17/341 (4%) Query: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIF----KNGAHYYPITLG 58 S+V G +R+ IPE +EV +K+ S G+CGSD+ + P+ LG Sbjct: 9 SLVVHGPGDLRLENYPIPE-PGPNEVLLKMHSVGICGSDVHYWQHGRIGDFVVKKPMVLG 67 Query: 59 HEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRD-GGF 117 HE SG + VGS V L PGD VA P P T C G Y+ F + D G Sbjct: 68 HEASGTVVKVGSLVRHLQPGDRVAIQPGAPRQTDEFCKIGRYNLSPTIFFCATPPDDGNL 127 Query: 118 AEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAI 177 + + LP ++ E+GA IEP++VG+HA A V++ GAG IGL+ + Sbjct: 128 CRFYKHNANFCYKLPDNVTFEEGALIEPLSVGIHACRRAGVTLGNKVLVCGAGPIGLVNL 187 Query: 178 QCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRF--NQLILE 235 A A+GA V D+S+ +L+ AK GA S S ++ + L ++ +E Sbjct: 188 LAAKAMGAAQVVVTDLSASRLSKAKEVGADFILEISNESPEEIAKKVEGLLGSKPEVTIE 247 Query: 236 TAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWP 295 GV +++ + L LVG + +TS +E+ + G + Y + WP Sbjct: 248 CTGVETSIQAGIYATHSGGTLVLVGLGSE---MTSVPLVHAATREVDIKGVF-RYCNTWP 303 Query: 296 GQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARN 336 A +L + ++++PL+ HR E +A + Sbjct: 304 -----MAISMLASKSVNVKPLVTHRFPLEKALEAFETSKKG 339 >2EER-A nrPDB Length = 347 Score = 290 bits (743), Expect = 5e-79, Method: Composition-based stats. Identities = 85/358 (23%), Positives = 151/358 (42%), Gaps = 23/358 (6%) Query: 1 MKSVVNDTDG-IVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPR---------IFKNGA 50 M+++ G +++ + IP+ K +V +KI ++G+C SD+ I ++ Sbjct: 1 MRAMRLVEIGKPLKLEDIPIPKPKGS-QVLIKIEAAGVCHSDVHMRQGRFGNLRIVEDLG 59 Query: 51 HYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIG 110 P+TLGHE +G I+ VG V GD VA P C C G C ++G Sbjct: 60 VKLPVTLGHEIAGRIEEVGDEVVGYSKGDLVAVNPWEGEGNCYYCRIGEEHLCDSPRWLG 119 Query: 111 SRRDGGFAEYIVVKR-KNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGA 169 DG +AEY++V K ++ L +E A A +K +++IGA Sbjct: 120 INYDGAYAEYVLVPHYKYLYKLRRLSAVEAAPLTCSGVTTYRAVRKASLDPSKTLVVIGA 179 Query: 170 -GTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELR 228 G +G +AIQ A A+ ++ +D+ E L AK GA N+S + + + Sbjct: 180 GGGLGTMAIQIAKAVSGATIIGVDVREEALEAAKRAGADYVINASSQDPVSEIRRITQGK 239 Query: 229 FNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWM 288 +++ +T+ + + + +VG DL + I E+ IGS + Sbjct: 240 GADAVIDLNNSEKTLSIYPYVLAKQGKYVMVGLFGADLKYHAP---LITLNEVQFIGSLV 296 Query: 289 NYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP 346 S + G L K ++P++ E +A+ ++ G+ +L+P Sbjct: 297 GNQSDFLG-----IMSLAEAGK--VKPMVTKTMKLEEANEAIDNLENFKAVGRQVLVP 347 >4EJ6-A nrPDB Length = 370 Score = 286 bits (732), Expect = 1e-77, Method: Composition-based stats. Identities = 110/348 (31%), Positives = 168/348 (48%), Gaps = 11/348 (3%) Query: 1 MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHE 60 MK+V ++ G + V IPE D++ VK+ + G+CG+D + P+TLGHE Sbjct: 24 MKAVRLESVGNISVRNVGIPE-PGPDDLLVKVEACGICGTDRHLLHGEFPSTPPVTLGHE 82 Query: 61 FSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEY 120 F G + GS V D+ PG + P + C CP+C G + C IG RDGGFAEY Sbjct: 83 FCGIVVEAGSAVRDIAPGARITGDPNISCGRCPQCQAGRVNLCRNLRAIGIHRDGGFAEY 142 Query: 121 IVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCA 180 ++V RK F +P + GAF EP+ LH L+ V I+G G IGLL +Q A Sbjct: 143 VLVPRKQAFEIPLTLDPVHGAFCEPLACCLHGVDLSGIKAGSTVAILGGGVIGLLTVQLA 202 Query: 181 VALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLREL--RFNQLILETAG 238 GA +V + K LA+ GA T + S + + L +++E AG Sbjct: 203 RLAGATTVILSTRQATKRRLAEEVGATATVDPSAGDVVEAIAGPVGLVPGGVDVVIECAG 262 Query: 239 VPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQE 298 V +TV+ + +A + ++G L Q + F IL +EL V+GS++N Sbjct: 263 VAETVKQSTRLAKAGGTVVILGVLPQGEKVEIEPF-DILFRELRVLGSFIN------PFV 315 Query: 299 WETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP 346 A+ L+ + ++ +I+ R S + + + A KVL+IP Sbjct: 316 HRRAADLVATGAIEIDRMISRRISLDEAPDVISNPAAAGEV-KVLVIP 362 >1E3J-A nrPDB Length = 352 Score = 284 bits (728), Expect = 2e-77, Method: Composition-based stats. Identities = 95/352 (26%), Positives = 158/352 (44%), Gaps = 21/352 (5%) Query: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYY----PITLG 58 S V +R+ + IPE K +DEV +++A G+CGSD+ + P+ +G Sbjct: 7 SAVLYKQNDLRLEQRPIPEPK-EDEVLLQMAYVGICGSDVHYYEHGRIADFIVKDPMVIG 65 Query: 59 HEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRR-DGGF 117 HE SG + VG V L GD VA P +PC C C +G Y+ C F + DG Sbjct: 66 HEASGTVVKVGKNVKHLKKGDRVAVEPGVPCRRCQFCKEGKYNLCPDLTFCATPPDDGNL 125 Query: 118 AEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAI 177 A Y V LP ++ +E+GA +EP++VG+HA A V++IGAG IGL+++ Sbjct: 126 ARYYVHAADFCHKLPDNVSLEEGALLEPLSVGVHACRRAGVQLGTTVLVIGAGPIGLVSV 185 Query: 178 QCAVALGAKSVTAIDISSEKLALAKSFGAMQ--TFNSSEMSAPQMQSVLRE--LRFNQLI 233 A A GA V S +L +AK+ GA + ++ + +R + Sbjct: 186 LAAKAYGA-FVVCTARSPRRLEVAKNCGADVTLVVDPAKEEESSIIERIRSAIGDLPNVT 244 Query: 234 LETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSP 293 ++ +G + + + + I L LVG Q + + +E+ + S Y + Sbjct: 245 IDCSGNEKCITIGINITRTGGTLMLVGMGSQ---MVTVPLVNACAREIDIK-SVFRYCND 300 Query: 294 WPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNA-MPGKVLL 344 +P A ++ + +++ L+ H E A + A KV++ Sbjct: 301 YP-----IALEMVASGRCNVKQLVTHSFKLEQTVDAFEAARKKADNTIKVMI 347 >2DQ4-A nrPDB Length = 343 Score = 284 bits (727), Expect = 4e-77, Method: Composition-based stats. Identities = 96/351 (27%), Positives = 162/351 (46%), Gaps = 15/351 (4%) Query: 1 MKSVVNDTDGI-VRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRI----FKNGAHYYPI 55 M+++ + + + +PE E+ V++ ++ +CG+DL + G P+ Sbjct: 1 MRALAKLAPEEGLTLVDRPVPE-PGPGEILVRVEAASICGTDLHIWKWDAWARGRIRPPL 59 Query: 56 TLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDG 115 GHEFSG ++AVG GV GD V+ + C CP C G Y C +G RDG Sbjct: 60 VTGHEFSGVVEAVGPGVRRPQVGDHVSLESHIVCHACPACRTGNYHVCLNTQILGVDRDG 119 Query: 116 GFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLL 175 GFAEY+VV +N + P D+P E A +EP +H + G K+V+I GAG IGL+ Sbjct: 120 GFAEYVVVPAENAWVNPKDLPFEVAAILEPFGNAVHTVYAGSGVSGKSVLITGAGPIGLM 179 Query: 176 AIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILE 235 A A GA + D + +LA A+ + A + N E ++ + +++LE Sbjct: 180 AAMVVRASGAGPILVSDPNPYRLAFARPY-ADRLVNPLEEDLLEVVRRVT-GSGVEVLLE 237 Query: 236 TAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWP 295 +G + + P + ++G + A G+++ + +T G + W Sbjct: 238 FSGNEAAIHQGLMALIPGGEARILGIPSDPIRFDLA--GELVMRGITAFG--IAGRRLW- 292 Query: 296 GQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP 346 Q W + L+ ++ L PL+ HR + +A + + KV+L P Sbjct: 293 -QTWMQGTALVYSGRVDLSPLLTHRLPLSRYREAFG-LLASGQAVKVILDP 341 >5VM2-A nrPDB Length = 347 Score = 283 bits (723), Expect = 1e-76, Method: Composition-based stats. Identities = 94/342 (27%), Positives = 160/342 (46%), Gaps = 20/342 (5%) Query: 4 VVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYP------ITL 57 + G +++ + IP + +DEV +K+ G+CGSD+ F++G P I L Sbjct: 6 AILQVPGTMKIISAEIP-VPKEDEVLIKVEYVGICGSDVH-GFESGPFIPPKDPNQEIGL 63 Query: 58 GHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRD--G 115 GHE +G + AVGS V PGD V P +PC C CL+G Y+ C DF+ ++ + G Sbjct: 64 GHECAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYRG 123 Query: 116 GFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLL 175 Y+ + LP +M +G +EP VG+HA LA K +II+GAG IGL+ Sbjct: 124 ALTHYLCHPESFTYKLPDNMDTMEGTLVEPAAVGMHAAMLADVKPGKKIIILGAGCIGLM 183 Query: 176 AIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILE 235 +Q LGA + +D+ ++LA+A+ GA N ++ E ++ E Sbjct: 184 TLQACKCLGATEIAVVDVLEKRLAMAEQLGATVVINGAKEDTIARCQQFTEDMGADIVFE 243 Query: 236 TAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWP 295 TAG TV+ A + ++ +VGT+ + +E+T+ + Y++ +P Sbjct: 244 TAGSAVTVKQAPYLVMRGGKIMIVGTVPGASAINFLKIN----REVTIQ-TVFRYANRYP 298 Query: 296 GQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNA 337 ++ + ++ ++ H + QA + N Sbjct: 299 -----VTIEAISSGRFDVKSMVTHIYDYRDVQQAFEESVNNK 335 >3PII-A nrPDB Length = 339 Score = 278 bits (712), Expect = 2e-75, Method: Composition-based stats. Identities = 88/349 (25%), Positives = 140/349 (40%), Gaps = 20/349 (5%) Query: 1 MKSVVNDTD-GIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGA--HYYPITL 57 MK+ V + +++ E P I + EV V+I + G+C +DL + P+ Sbjct: 1 MKAAVVEQFKEPLKIKEVEKPTISY-GEVLVRIKACGVCHTDLHAAHGDWPVKPKLPLIP 59 Query: 58 GHEFSGYIDAVGSGVDDLHPGDAVACVPLLP-CFTCPECLKGFYSQCAKYDFIGSRRDGG 116 GHE G ++ VG GV L GD V L C C CL G + C G DGG Sbjct: 60 GHEGVGIVEEVGPGVTHLKVGDRVGIPWLYSACGHCDYCLSGQETLCEHQKNAGYSVDGG 119 Query: 117 FAEYIVVKRKNVFALPTDMPIEDGAFI-EPITVGLHAFHLAQGCENKNVIIIGAGTIGLL 175 +AEY V +P ++ E+ A I A + + V I G G G + Sbjct: 120 YAEYCRAAADYVVKIPDNLSFEEAAPIFCAGVTTYKALKVTGAKPGEWVAIYGIGGFGHV 179 Query: 176 AIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILE 235 A+Q A A+G +V A+DI EKL LAK GA N + A + ++ + Sbjct: 180 AVQYAKAMGL-NVVAVDIGDEKLELAKELGADLVVNPLKEDAAKFMK--EKVGGVHAAVV 236 Query: 236 TAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWP 295 TA + A LVG +++ + + + +IGS + Sbjct: 237 TAVSKPAFQSAYNSIRRGGACVLVGLPPEEMPI---PIFDTVLNGIKIIGSIVGTR---- 289 Query: 296 GQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 ++ + A + E K+ I E + + + + G+V+L Sbjct: 290 -KDLQEALQFAAEGKV---KTIIEVQPLEKINEVFDRMLKGQINGRVVL 334 >5KIA-A nrPDB Length = 351 Score = 276 bits (706), Expect = 1e-74, Method: Composition-based stats. Identities = 90/349 (25%), Positives = 157/349 (44%), Gaps = 16/349 (4%) Query: 1 MKSVVNDTDGI-VRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRI----FKNGAHYYPI 55 MK++ G + + PE+ H ++V +KI + +CG+D+ + P+ Sbjct: 9 MKALAKLERGPGLTLTRVKKPEVGH-NDVLIKIRRTAICGTDIHIWKWDDWAQKTIPVPM 67 Query: 56 TLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDG 115 +GHE+ G I +G V GD V+ + C C C G C +G R+G Sbjct: 68 HVGHEYVGEIVEMGQEVRGFSIGDRVSGEGHITCGFCRNCRAGRRHLCRNTVGVGVNREG 127 Query: 116 GFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLL 175 FAEY+ + N F +P ++ + A +P H L+ ++V+I GAG IG++ Sbjct: 128 AFAEYLAIPAFNAFKIPPEISDDLAAIFDPFGNATHTA-LSFNLVGEDVLITGAGPIGVM 186 Query: 176 AIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILE 235 A+ A +GA++V DI+ +L LA+ GA + N S S + + L + LE Sbjct: 187 AVAIAKHVGARNVVITDINDYRLDLARRMGATRAVNVSRESLRDVMADLHMTEGFDVGLE 246 Query: 236 TAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWP 295 +GVP +E ++AL+G T+ + +++ K L + G + Sbjct: 247 MSGVPSAFTSLLESMNHGGKVALLGIPPAQ---TAIDWNQVIFKGLEIKGIY----GREM 299 Query: 296 GQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 + W +L L L P+I HR + + + + + + GKV+L Sbjct: 300 FETWYKMVAMLQSG-LDLSPIITHRFAVDDYEKGFAAML-SGESGKVIL 346 >1HSO-A nrPDB Length = 374 Score = 275 bits (704), Expect = 2e-74, Method: Composition-based stats. Identities = 87/372 (23%), Positives = 148/372 (39%), Gaps = 39/372 (10%) Query: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFS 62 +V+ + + E + EVR+K+ + G+CG+D + P+ LGHE + Sbjct: 12 AVLWELKKPFSIEEVEV-APPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAA 70 Query: 63 GYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFI---GSRRDG---- 115 G +++VG GV + PGD V + + C C C + C K D G+ +DG Sbjct: 71 GIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRF 130 Query: 116 --------------GFAEYIVVKRKNVFALPTDMPIEDGAFI-EPITVGLH-AFHLAQGC 159 F++Y VV V + P+E I + G A ++A+ Sbjct: 131 TCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVT 190 Query: 160 ENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQ 219 + G G +GL AI A GA + A+DI+ +K A AK GA + N + P Sbjct: 191 PGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP- 249 Query: 220 MQSVLREL--RFNQLILETAGVPQTVELAVEIAGPH-AQLALVGTLHQDLHLTSATFGKI 276 +Q VL+E+ E G T+ ++ +VG +L+ + Sbjct: 250 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLL 309 Query: 277 LRKELTVIGSWMNYSSPWPGQEWETASRLLTE---RKLSLEPLIAHRGSFESFAQAVRDI 333 G + + E +L+ + +K SL+ LI H FE + D+ Sbjct: 310 T-------GRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGF-DL 361 Query: 334 ARNAMPGKVLLI 345 + + +L+ Sbjct: 362 LHSGKSIRTILM 373 >3COS-A nrPDB Length = 381 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 83/379 (21%), Positives = 152/379 (40%), Gaps = 48/379 (12%) Query: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHY-YPITLGHEF 61 ++ + + + E + EVR++I ++ LC +D I +P+ +GHE Sbjct: 14 AIAWEAGKPLCIEEVEV-APPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEA 72 Query: 62 SGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAK---------------- 105 +G ++++G GV ++ PGD V + C C CL + C K Sbjct: 73 AGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMED 132 Query: 106 ------------YDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAFI-EPITVGLHA 152 Y F G+ F++Y VV N+ + D +E + + G A Sbjct: 133 KTSRFTCKGKPVYHFFGTST---FSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGA 189 Query: 153 F-HLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFN 211 + A+ + G G +GL A+ A GA + IDI+SEK AK+ GA N Sbjct: 190 AINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLN 249 Query: 212 SSEMSAPQMQSVLR-ELRFNQLILETAGVPQTVELAVEI-AGPHAQLALVGTLHQDLHLT 269 ++ P + ++ L+ AG +T++ A++ +G LT Sbjct: 250 PRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLT 309 Query: 270 SATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLT---ERKLSLEPLIAHRGSFESF 326 E +IG +N + + ++ +L+T +K +L+ L+ H F+ Sbjct: 310 VFP-------EELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKI 362 Query: 327 AQAVRDIARNAMPGKVLLI 345 ++A D+ + +LI Sbjct: 363 SEAF-DLMNQGKSIRTILI 380 >1HSZ-A nrPDB Length = 374 Score = 271 bits (694), Expect = 2e-73, Method: Composition-based stats. Identities = 84/368 (22%), Positives = 143/368 (38%), Gaps = 33/368 (8%) Query: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFS 62 +V+ + + + + EVR+K+ + G+C +D + N P+ LGHE + Sbjct: 12 AVLWEVKKPFSIEDVEV-APPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAA 70 Query: 63 GYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFI---GSRRDG---- 115 G +++VG GV + PGD V + C C C + C K D G+ +DG Sbjct: 71 GIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRF 130 Query: 116 --------------GFAEYIVVKRKNVFALPTDMPIEDGAFI-EPITVGLH-AFHLAQGC 159 F++Y VV V + P+E I + G A ++A+ Sbjct: 131 TCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVT 190 Query: 160 ENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQ 219 + G G +GL A+ A GA + A+DI+ +K A AK GA + N + P Sbjct: 191 PGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP- 249 Query: 220 MQSVLREL--RFNQLILETAGVPQTVELAVEIAGPH-AQLALVGTLHQDLHLTSATFGKI 276 +Q VL+E+ E G T+ ++ +VG +L+ + Sbjct: 250 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLL 309 Query: 277 LRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARN 336 + G+ Y + +K SL+ LI H FE + D+ + Sbjct: 310 TGRTW--KGAV--YGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGF-DLLHS 364 Query: 337 AMPGKVLL 344 + +L Sbjct: 365 GKSIRTVL 372 >1U3W-A nrPDB Length = 374 Score = 270 bits (691), Expect = 5e-73, Method: Composition-based stats. Identities = 86/371 (23%), Positives = 147/371 (39%), Gaps = 39/371 (10%) Query: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFS 62 +V+ + + E + EVR+K+ ++G+C SD + N P+ LGHE + Sbjct: 12 AVLWELKKPFSIEEVEV-APPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAA 70 Query: 63 GYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFI---GSRRDG---- 115 G +++VG GV + PGD V + C C C + C K D G+ +DG Sbjct: 71 GIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRF 130 Query: 116 --------------GFAEYIVVKRKNVFALPTDMPIEDGAFI-EPITVGLH-AFHLAQGC 159 F++Y VV V + P+E I + G A +A+ Sbjct: 131 TCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVT 190 Query: 160 ENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQ 219 + G G +GL + A GA + A+DI+ +K A AK GA + N + P Sbjct: 191 PGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP- 249 Query: 220 MQSVLREL--RFNQLILETAGVPQTVELAVEIAGPH-AQLALVGTLHQDLHLTSATFGKI 276 +Q VL+E+ E G T+ ++ +VG +L+ + Sbjct: 250 IQEVLKEMTDGGVDFSFEVIGQLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLL 309 Query: 277 LRKELTVIGSWMNYSSPWPGQEWETASRLLTE---RKLSLEPLIAHRGSFESFAQAVRDI 333 G + + E+ +L+ + +K SL+ LI + FE + D+ Sbjct: 310 T-------GRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNVLPFEKINEGF-DL 361 Query: 334 ARNAMPGKVLL 344 R+ + +L Sbjct: 362 LRSGKSIRTVL 372 >3MEQ-A nrPDB Length = 365 Score = 268 bits (686), Expect = 2e-72, Method: Composition-based stats. Identities = 91/351 (25%), Positives = 151/351 (43%), Gaps = 22/351 (6%) Query: 1 MKSVVNDTDG-IVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYY--PITL 57 MK+ V G + + E IP+ +++V I +SG+C +DL + P Sbjct: 26 MKAAVVRAFGKPLTIDEVPIPQ-PGPGQIQVAIQASGVCHTDLHAAEGDWPVKPNPPFIP 84 Query: 58 GHEFSGYIDAVGSGVDDLHPGDAVACVPLL-PCFTCPECLKGFYSQCAKYDFIGSRRDGG 116 GHE G++ AVGSGV + GD V L C C CL G+ + C + G +GG Sbjct: 85 GHEGVGFVSAVGSGVKHVKEGDRVGIPWLYTACGHCRHCLGGWETLCEEQLNTGYSVNGG 144 Query: 117 FAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQG---CENKNVIIIGAGTIG 173 FAEY+V V LP ++ + A + + G+ + + V+I G G +G Sbjct: 145 FAEYVVADPNFVGHLPKNIDFNEIAPV--LCAGVTVYKGLKVTDTKPGDWVVISGIGGLG 202 Query: 174 LLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLI 233 +A+Q A A+G +V A+DI KL LA+ GA T N+ ++ P Q + Sbjct: 203 HMAVQYARAMGL-NVAAVDIDDRKLDLARRLGATVTVNAKTVADPAAYIRKETDGGAQGV 261 Query: 234 LETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSP 293 L TA P+ E A+ + ++L G D L+ + +TV GS + Sbjct: 262 LVTAVSPKAFEQALGMVARGGTVSLNGLPPGDFPLSIFNM---VLNGVTVRGSIVGTR-- 316 Query: 294 WPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 + + + + K+ G E D+ + + G++++ Sbjct: 317 ---LDLQESLDFAADGKVKAT---IQTGKLEDINAIFDDMRQGNIEGRIVM 361 >4CPD-A nrPDB Length = 347 Score = 268 bits (686), Expect = 2e-72, Method: Composition-based stats. Identities = 100/353 (28%), Positives = 150/353 (42%), Gaps = 17/353 (4%) Query: 1 MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHE 60 M++VV + V V E P ++H + V++ +G+CGSDL LGHE Sbjct: 1 MRAVVFENKERVAVKEVNAPRLQHPLDALVRVHLAGICGSDLHLYHGKIPVLPGSVLGHE 60 Query: 61 FSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGS-----RRDG 115 F G ++AVG G+ DL PGD V + C TCP C + Y+ C + G G Sbjct: 61 FVGQVEAVGEGIQDLQPGDWVVGPFHIACGTCPYCRRHQYNLCERGGVYGYGPMFGNLQG 120 Query: 116 GFAEYIVVKRKNV--FALPTDMPIEDGAFIEP-ITVGLHAFHLAQGCENKNVIIIGAGTI 172 AE + V NV LP ++ E F ++ Q +V +IGAG + Sbjct: 121 AQAEILRVPFSNVNLRKLPPNLSPERAIFAGDILSTAYGGLIQGQLRPGDSVAVIGAGPV 180 Query: 173 GLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQL 232 GL+AI+ A LGA + AID E+L A S GA+ N+ + + + L Sbjct: 181 GLMAIEVAQVLGASKILAIDRIPERLERAASLGAIP-INAEQENPVRRVRSETNDEGPDL 239 Query: 233 ILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSS 292 +LE G T+ LA+E+ P +++ VG + L K+LT N Sbjct: 240 VLEAVGGAATLSLALEMVRPGGRVSAVGVDNAPSF--PFPLASGLVKDLTFRIGLANVH- 296 Query: 293 PWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLI 345 + LL +L E +++H E + R KVLL+ Sbjct: 297 ----LYIDAVLALLASGRLQPERIVSHYLPLEEAPRGYELFDRK-EALKVLLV 344 >4ILK-A nrPDB Length = 359 Score = 267 bits (683), Expect = 4e-72, Method: Composition-based stats. Identities = 109/347 (31%), Positives = 160/347 (46%), Gaps = 15/347 (4%) Query: 1 MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFK-NGAHYYPITLGH 59 MKS++ + + + E IP EVRVK+ +G+CGSD N YP +GH Sbjct: 21 MKSILIEKPNQLSIIEREIP-TPSAGEVRVKVKLAGICGSDSHIYRGHNPFAKYPRVIGH 79 Query: 60 EFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAE 119 EF G IDAVG GV+ G+ VA P++ C C C G + C +G DGGF+E Sbjct: 80 EFFGVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNVCTTLAVLGVHADGGFSE 139 Query: 120 YIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQC 179 Y VV KN + +P + + IEP T+ + Q EN V++ GAG IGL +Q Sbjct: 140 YAVVPAKNAWKIPEAVADQYAVMIEPFTIAANVTGHGQPTENDTVLVYGAGPIGLTIVQV 199 Query: 180 AV-ALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAG 238 K+V D E+L AK GA N+S+ P +S + LI++ A Sbjct: 200 LKGVYNVKNVIVADRIDERLEKAKESGADWAINNSQT--PLGESFAEKGIKPTLIIDAAC 257 Query: 239 VPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQE 298 P ++ AV +A P A++ L+G + + I KEL++ S +N + Sbjct: 258 HPSILKEAVTLASPAARIVLMGFSSEPSEVIQQG---ITGKELSIFSSRLN------ANK 308 Query: 299 WETASRLLTERKLSLEPLIAHRGSFESFAQAVRDI-ARNAMPGKVLL 344 + L++ + E LI H F+ A A+ KVLL Sbjct: 309 FPVVIDWLSKGLIKPEKLITHTFDFQHVADAISLFELDQKHCCKVLL 355 >1LLU-A nrPDB Length = 342 Score = 266 bits (681), Expect = 8e-72, Method: Composition-based stats. Identities = 93/349 (26%), Positives = 143/349 (40%), Gaps = 20/349 (5%) Query: 1 MKSVVNDTDG-IVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGA--HYYPITL 57 MK+ V G +R+ E +P + +V VKI +SG+C +DL + P Sbjct: 7 MKAAVVHAYGAPLRIEEVKVP-LPGPGQVLVKIEASGVCHTDLHAAEGDWPVKPPLPFIP 65 Query: 58 GHEFSGYIDAVGSGVDDLHPGDAVACVPLL-PCFTCPECLKGFYSQCAKYDFIGSRRDGG 116 GHE GY+ AVGSGV + GD V L C C CL G+ + C G +GG Sbjct: 66 GHEGVGYVAAVGSGVTRVKEGDRVGIPWLYTACGCCEHCLTGWETLCESQQNTGYSVNGG 125 Query: 117 FAEYIVVKRKNVFALPTDMPI-EDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLL 175 +AEY++ V LP ++ E + + V I G G +G + Sbjct: 126 YAEYVLADPNYVGILPKNVEFAEIAPILCAGVTVYKGLKQTNARPGQWVAISGIGGLGHV 185 Query: 176 AIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILE 235 A+Q A A+G V AIDI KL LA+ GA T N+ + + R++ +L Sbjct: 186 AVQYARAMGLH-VAAIDIDDAKLELARKLGASLTVNARQEDPVEAIQ--RDIGGAHGVLV 242 Query: 236 TAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWP 295 TA A+ +A +ALVG D ++ K L + GS + Sbjct: 243 TAVSNSAFGQAIGMARRGGTIALVGLPPGDF---PTPIFDVVLKGLHIAGSIVGTR---- 295 Query: 296 GQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 + + A E + H G + Q + + + G+++L Sbjct: 296 -ADLQEALDFAGEGLVKAT---IHPGKLDDINQILDQMRAGQIEGRIVL 340 >4RQU-A nrPDB Length = 375 Score = 265 bits (678), Expect = 2e-71, Method: Composition-based stats. Identities = 88/370 (23%), Positives = 146/370 (39%), Gaps = 35/370 (9%) Query: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHY-YPITLGHEF 61 +V + + + E + + EVR+KI + LC +D+ G +P GHE Sbjct: 9 AVAWEAGKPLVIEEVEV-APPQKHEVRIKILFTSLCHTDVYFWEAKGQTPLFPRIFGHEA 67 Query: 62 SGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCA----KYDFIGSRRDG-- 115 G +++VG GV DL PGD V + C C C + C + G DG Sbjct: 68 GGIVESVGEGVTDLQPGDHVLPIFTGECGECRHCHSEESNMCDLLRINTERGGMIHDGES 127 Query: 116 ----------------GFAEYIVVKRKNVFALPTDMPIEDGAFI-EPITVGLHA-FHLAQ 157 F+EY VV V + D P++ + ++ GL A ++A+ Sbjct: 128 RFSINGKPIYHFLGTSTFSEYTVVHSGQVAKINPDAPLDKVCIVSCGLSTGLGATLNVAK 187 Query: 158 GCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSA 217 + ++V I G G +GL A + A GA + +D +S++ AK FG + N + Sbjct: 188 PKKGQSVAIFGLGAVGLGAAEGARIAGASRIIGVDFNSKRFDQAKEFGVTECVNPKDHDK 247 Query: 218 PQMQSVLREL--RFNQLILETAGVPQTVELAVEIAGPHAQLA-LVGTLHQDLHLTSATFG 274 P +Q V+ E+ +E G Q + A E +A LVG +D + Sbjct: 248 P-IQQVIAEMTDGGVDRSVECTGSVQAMIQAFECVHDGWGVAVLVGVPSKDDAFKTHPMN 306 Query: 275 KILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIA 334 E T+ G++ + P + ++L LE I H F +A D Sbjct: 307 --FLNERTLKGTFFG--NYKPKTDIPGVVEKYMNKELELEKFITHTVPFSEINKAF-DYM 361 Query: 335 RNAMPGKVLL 344 + ++ Sbjct: 362 LKGESIRCII 371 >1EE2-A nrPDB Length = 373 Score = 264 bits (675), Expect = 4e-71, Method: Composition-based stats. Identities = 82/370 (22%), Positives = 147/370 (39%), Gaps = 38/370 (10%) Query: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFS 62 +V+ + + E + EVR+K+ ++G+C SD + P+ GHE + Sbjct: 12 AVLWEQKKPFSIEEVEV-APPKAHEVRIKMVAAGICRSDDHVVSGTLVAPLPVIAGHEAA 70 Query: 63 GYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFI--GSRRDG----- 115 G ++++G GV + PGD V + + C C C + C K + G+ +DG Sbjct: 71 GIVESIGEGVTTVRPGDKVIPLFIPQCGKCSVCKHPEGNLCLKNLSMPRGTMQDGTSRFT 130 Query: 116 -------------GFAEYIVVKRKNVFALPTDMPIEDGAFI-EPITVGLH-AFHLAQGCE 160 F++Y VV +V + P+E + + G A +A+ + Sbjct: 131 CRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLVGCGFSTGYGSAVKVAKVTQ 190 Query: 161 NKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQM 220 + G G +GL I A GA + +DI+ +K A AK GA + N + P + Sbjct: 191 GSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATECVNPQDYKKP-I 249 Query: 221 QSVLREL--RFNQLILETAGVPQTVELAVEIAGPH-AQLALVGTLHQDLHLTSATFGKIL 277 Q VL E+ E G T+ A+ +VG +L+ + Sbjct: 250 QEVLTEMSNGGVDFSFEVIGRLDTMVAALSCCQEAYGVSVIVGVPPDSQNLSMNPMLLLS 309 Query: 278 RKELTVIGSWMNYSSPWPGQEWETASRLLTE---RKLSLEPLIAHRGSFESFAQAVRDIA 334 G + + ++ +L+ + +K +L+PLI H FE + D+ Sbjct: 310 -------GRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGF-DLL 361 Query: 335 RNAMPGKVLL 344 R+ + +L Sbjct: 362 RSGKSIRTIL 371 >1R37-A nrPDB Length = 347 Score = 263 bits (671), Expect = 1e-70, Method: Composition-based stats. Identities = 84/358 (23%), Positives = 148/358 (41%), Gaps = 23/358 (6%) Query: 1 MKSVVNDTDG-IVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPR---------IFKNGA 50 M++V G + + E +P+ K +V +K+ ++G+C SD+ I ++ Sbjct: 1 MRAVRLVEIGKPLSLQEIGVPKPKGP-QVLIKVEAAGVCHSDVHMRQGRFGNLRIVEDLG 59 Query: 51 HYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIG 110 P+TLGHE +G I+ VG V GD VA P C C G C ++G Sbjct: 60 VKLPVTLGHEIAGKIEEVGDEVVGYSKGDLVAVNPWQGEGNCYYCRIGEEHLCDSPRWLG 119 Query: 111 SRRDGGFAEYIVVKR-KNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKN-VIIIG 168 DG +AEY++V K ++ L +E A A K +++ Sbjct: 120 INFDGAYAEYVIVPHYKYMYKLRRLNAVEAAPLTCSGITTYRAVRKASLDPTKTLLVVGA 179 Query: 169 AGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELR 228 G +G +A+Q A A+ ++ +D+ E + AK GA N+S + E + Sbjct: 180 GGGLGTMAVQIAKAVSGATIIGVDVREEAVEAAKRAGADYVINASMQDPLAEIRRITESK 239 Query: 229 FNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWM 288 +++ +T+ + + + +VG DLH + I E+ +GS + Sbjct: 240 GVDAVIDLNNSEKTLSVYPKALAKQGKYVMVGLFGADLHYHAP---LITLSEIQFVGSLV 296 Query: 289 NYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP 346 S + G RL K ++P+I E +A+ ++ G+ +LIP Sbjct: 297 GNQSDFLG-----IMRLAEAGK--VKPMITKTMKLEEANEAIDNLENFKAIGRQVLIP 347 >4Z6K-A nrPDB Length = 346 Score = 262 bits (670), Expect = 1e-70, Method: Composition-based stats. Identities = 83/349 (23%), Positives = 142/349 (40%), Gaps = 20/349 (5%) Query: 1 MKSVVNDTDGI-VRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYY--PITL 57 MK+ V G +++ E IP E+ VK+ +SG+C +DL + + P Sbjct: 1 MKAAVLHEFGQSLQIEEVDIP-TPGAGEIVVKMQASGVCHTDLHAVEGDWPVKPSPPFIP 59 Query: 58 GHEFSGYIDAVGSGVDDLHPGDAVACVPLLP-CFTCPECLKGFYSQCAKYDFIGSRRDGG 116 GHE G I AVG GV + GD V L C C CL G+ + C G +G Sbjct: 60 GHEGVGLITAVGEGVTHVKEGDRVGVAWLYSACGHCTHCLGGWETLCESQQNSGYSVNGS 119 Query: 117 FAEYIVVKRKNVFALPTDMP-IEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLL 175 FAEY++ V +P + IE + + V+I G G +G + Sbjct: 120 FAEYVLANANYVGIIPESVDSIEIAPVLCAGVTVYKGLKMTDTKPGDWVVISGIGGLGHM 179 Query: 176 AIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILE 235 A+Q A+A+G +V A+DI +KLA AK GA T N+ + +E+ L Sbjct: 180 AVQYAIAMGL-NVAAVDIDDDKLAFAKKLGAKVTVNAKNTDPAEYLQ--KEIGGAHGALV 236 Query: 236 TAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWP 295 TA + + A+ + L G D ++ + +T+ GS + Sbjct: 237 TAVSAKAFDQALSMLRRGGTLVCNGLPPGDFPVSIF---DTVLNGITIRGSIVGTR---- 289 Query: 296 GQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 + + + + K ++ + E+ + + + G++++ Sbjct: 290 -LDLQESLDMAAAGK--VKATVTAE-PLENINDIFERMRQGKIEGRIVI 334 >3S2F-A nrPDB Length = 340 Score = 260 bits (665), Expect = 5e-70, Method: Composition-based stats. Identities = 87/349 (24%), Positives = 143/349 (40%), Gaps = 20/349 (5%) Query: 1 MKSVVNDTDG-IVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHY--YPITL 57 MK+ V G + + E +P+ +V+VKI +SG+C +DL + P Sbjct: 3 MKAAVVRAFGAPLTIDEVPVPQ-PGPGQVQVKIEASGVCHTDLHAADGDWPVKPTLPFIP 61 Query: 58 GHEFSGYIDAVGSGVDDLHPGDAVACVPLLP-CFTCPECLKGFYSQCAKYDFIGSRRDGG 116 GHE GY+ AVGSGV + GD V L C C CL+G+ + C K G +GG Sbjct: 62 GHEGVGYVSAVGSGVSRVKEGDRVGVPWLYSACGYCEHCLQGWETLCEKQQNTGYSVNGG 121 Query: 117 FAEYIVVKRKNVFALPTDMPI-EDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLL 175 + EY+V V LP + E + + + V+I G G +G + Sbjct: 122 YGEYVVADPNYVGLLPDKVGFVEIAPILCAGVTVYKGLKVTDTRPGQWVVISGIGGLGHV 181 Query: 176 AIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILE 235 A+Q A A+G V A+DI KL LA+ GA N+ + +E+ +L Sbjct: 182 AVQYARAMGL-RVAAVDIDDAKLNLARRLGAEVAVNARDTDPAAWLQ--KEIGGAHGVLV 238 Query: 236 TAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWP 295 TA P+ A+ + +AL G D ++ K +T+ GS + S Sbjct: 239 TAVSPKAFSQAIGMVRRGGTIALNGLPPGDFG---TPIFDVVLKGITIRGSIVGTRS--- 292 Query: 296 GQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 + + + ++ ++ + + + G+V+L Sbjct: 293 --DLQESLDFAAHG--DVKATVS-TAKLDDVNDVFGRLREGKVEGRVVL 336 >1E3E-A nrPDB Length = 376 Score = 258 bits (660), Expect = 2e-69, Method: Composition-based stats. Identities = 84/375 (22%), Positives = 148/375 (39%), Gaps = 45/375 (12%) Query: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFS 62 ++ T + + E + EVR+++ ++ +C +D+ +P+ LGHE + Sbjct: 12 AIAWKTGSPLCIEEIEV-SPPKACEVRIQVIATCVCPTDINATDPKKKALFPVVLGHECA 70 Query: 63 GYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRR--------- 113 G +++VG GV + PGD V C C CL + C K Sbjct: 71 GIVESVGPGVTNFKPGDKVIPFFAPQCKRCKLCLSPLTNLCGKLRNFKYPTIDQELMEDR 130 Query: 114 ----------------DGGFAEYIVVKRKNVFALPTDMPIEDGAFI-EPITVGLHAF-HL 155 F++Y VV N+ + + +E I + G A + Sbjct: 131 TSRFTCKGRSIYHFMGVSSFSQYTVVSEANLARVDDEANLERVCLIGCGFSSGYGAAINT 190 Query: 156 AQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEM 215 A+ + G G +GL AI GA + AIDI+ EK AK+ GA N E+ Sbjct: 191 AKVTPGSTCAVFGLGCVGLSAIIGCKIAGASRIIAIDINGEKFPKAKALGATDCLNPREL 250 Query: 216 SAPQMQSVLREL--RFNQLILETAGVPQTVELAVEI-AGPHAQLALVGTLHQDLHLTSAT 272 P +Q V+ EL L+ AG QT++ AV+ +VG ++ + + Sbjct: 251 DKP-VQDVITELTAGGVDYSLDCAGTAQTLKAAVDCTVLGWGSCTVVGAKVDEMTIPTVD 309 Query: 273 FGKILRKELTVIGSWMNYSSPWPGQEWETASRLLT---ERKLSLEPLIAHRGSFESFAQA 329 ++G +N + + ++ L++ +K L+ L+ H FES A Sbjct: 310 V---------ILGRSINGTFFGGWKSVDSVPNLVSDYKNKKFDLDLLVTHALPFESINDA 360 Query: 330 VRDIARNAMPGKVLL 344 + D+ + + +L Sbjct: 361 I-DLMKEGKSIRTIL 374 >1H2B-A nrPDB Length = 359 Score = 258 bits (659), Expect = 3e-69, Method: Composition-based stats. Identities = 86/354 (24%), Positives = 154/354 (43%), Gaps = 23/354 (6%) Query: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNG----AHYYPITLG 58 + +++ + +R+ + P ++ + +V V+IA +G+C +DL + P TLG Sbjct: 19 ARLHEYNKPLRIEDVDYPRLEGRFDVIVRIAGAGVCHTDLHLVQGMWHELLQPKLPYTLG 78 Query: 59 HEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFA 118 HE GYI+ V GV+ L GD V P + TC C G C +F G DGGFA Sbjct: 79 HENVGYIEEVAEGVEGLEKGDPVILHPAVTDGTCLACRAGEDMHCENLEFPGLNIDGGFA 138 Query: 119 EYIVVKRKNVFALPTDMPIEDGAFIEPIT-VGLHAFHLAQGC-----ENKNVIIIGAGTI 172 E++ ++V LP D+ E + P+ G+ A+ + V I+G G + Sbjct: 139 EFMRTSHRSVIKLPKDISREKLVEMAPLADAGITAYRAVKKAARTLYPGAYVAIVGVGGL 198 Query: 173 GLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQL 232 G +A+Q + +V A+D+ EKL LA+ GA ++ + L R + Sbjct: 199 GHIAVQLLKVMTPATVIALDVKEEKLKLAERLGADHVVDARR-DPVKQVMELTRGRGVNV 257 Query: 233 ILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSS 292 ++ G TV+ + G +L +VG + +++ E++ GS + Sbjct: 258 AMDFVGSQATVDYTPYLLGRMGRLIIVGYGGE----LRFPTIRVISSEVSFEGSLVGN-- 311 Query: 293 PWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP 346 E L + K+ +E + H + + + + + G+ +LIP Sbjct: 312 ---YVELHELVTLALQGKVRVE-VDIH--KLDEINDVLERLEKGEVLGRAVLIP 359 >1D1T-A nrPDB Length = 373 Score = 257 bits (656), Expect = 6e-69, Method: Composition-based stats. Identities = 81/370 (21%), Positives = 141/370 (38%), Gaps = 38/370 (10%) Query: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFS 62 +V+ + + E + EVR+KI ++G+C +D I +P+ +GHE + Sbjct: 12 AVLWEQKQPFSIEEIEV-APPKTKEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEAT 70 Query: 63 GYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRR--DG----- 115 G ++++G GV + PGD V + L C C C + C + D G DG Sbjct: 71 GIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFT 130 Query: 116 -------------GFAEYIVVKRKNVFALPTDMPIEDGAFI-EPITVGLH-AFHLAQGCE 160 F EY VV +V + P E I + G A + Sbjct: 131 CKGKPVHHFLNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKP 190 Query: 161 NKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQM 220 ++ G G +GL I + GA + ID++ +K A + GA + + + + P + Sbjct: 191 GSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKP-I 249 Query: 221 QSVLRELRFNQL--ILETAGVPQTVELAVEIAGPH-AQLALVGTLHQDLHLTSATFGKIL 277 VL E+ N + E G +T+ A+ + +VG LT Sbjct: 250 SEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPM---- 305 Query: 278 RKELTVIGSWMNYSSPWPGQEWETASRLLTE---RKLSLEPLIAHRGSFESFAQAVRDIA 334 L G + + +L+TE +K L+ LI H F+ ++ + Sbjct: 306 ---LLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFE-LL 361 Query: 335 RNAMPGKVLL 344 + + +L Sbjct: 362 NSGQSIRTVL 371 >5YLN-A nrPDB Length = 356 Score = 254 bits (650), Expect = 3e-68, Method: Composition-based stats. Identities = 83/354 (23%), Positives = 139/354 (39%), Gaps = 19/354 (5%) Query: 1 MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYY-PITLGH 59 MK+ G+ + P I+ + V+I + +CG+DL I + LGH Sbjct: 5 MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHIIKGDVPTCQSGTILGH 64 Query: 60 EFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYD--FIGSRRDGGF 117 E G ++ VG GV + GD V + C C C KG Y+ C G DG Sbjct: 65 EGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYAHCEDEGGWIFGHLIDGMQ 124 Query: 118 AEYIVVKR--KNVFALPTDMPIEDGAFIEP-ITVGLH-AFHLAQGCENKNVIIIGAGTIG 173 AEY+ V ++ P D+ E + + G + +V IIG+G +G Sbjct: 125 AEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGVLKGKVEPGCSVAIIGSGPVG 184 Query: 174 LLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSE-MSAPQMQSVLRELRFNQL 232 L A+ A + +D+ +L A SFGA NSS+ A + L + R + Sbjct: 185 LAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVNSSDPEKAIKEIYDLTDGRGVDV 244 Query: 233 ILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSS 292 +E G+P T + +I G +A G + + K+ + + V ++ ++ Sbjct: 245 AIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEFD---LDKLWIRNINVTTGLVSTNT 301 Query: 293 PWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNA--MPGKVLL 344 + L K+ E L+ H +A ++ A KV++ Sbjct: 302 T------PQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSKAADHHAIKVII 349 >1MC5-A nrPDB Length = 374 Score = 254 bits (650), Expect = 3e-68, Method: Composition-based stats. Identities = 82/377 (21%), Positives = 148/377 (39%), Gaps = 50/377 (13%) Query: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFK-NGAHYYPITLGHEF 61 +V + + + E + EVR+KI ++ +C +D + + +P+ LGHE Sbjct: 11 AVAWEAGKPLSIEEIEV-APPKAHEVRIKIIATAVCHTDAYTLSGADPEGCFPVILGHEG 69 Query: 62 SGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFI---GSRRDG--- 115 +G +++VG GV L GD V + + C C CL + C K G DG Sbjct: 70 AGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKGLMPDGTSR 129 Query: 116 ---------------GFAEYIVVKRKNVFALPTDMPIEDGAFI-EPITVGLH-AFHLAQG 158 F+EY VV +V + P++ + I+ G A + A+ Sbjct: 130 FTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYGAAVNTAKL 189 Query: 159 CENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAP 218 + G G +GL I GA + +DI+ +K A AK FGA + N + S P Sbjct: 190 EPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECINPQDFSKP 249 Query: 219 QMQSVLREL--RFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKI 276 +Q VL E+ E G + + A+E H+ ++ Sbjct: 250 -IQEVLIEMTDGGVDYSFECIGNVKVMRAALEA------------CHKGWGVSVVVGVAA 296 Query: 277 LRKELTVIGSWMNYSSPWPGQEW------ETASRLLTE---RKLSLEPLIAHRGSFESFA 327 +E+ + W G + E+ +L++E +K+ ++ + H SF+ Sbjct: 297 SGEEIATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEIN 356 Query: 328 QAVRDIARNAMPGKVLL 344 +A + + + ++ Sbjct: 357 KAFE-LMHSGKSIRTVV 372 >4OH1-A nrPDB Length = 351 Score = 254 bits (648), Expect = 5e-68, Method: Composition-based stats. Identities = 89/346 (25%), Positives = 149/346 (43%), Gaps = 23/346 (6%) Query: 7 DTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGA-------HYYPITLGH 59 +T G V + E+ +PE K + E+R+K+ + +CGSD + N P++ GH Sbjct: 16 NTMGTVDMMEAPMPEPKDE-EIRIKVVYASICGSDTHILTGNLGEMESTTRSMLPMSFGH 74 Query: 60 EFSGYIDAVGSGVD--DLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGF 117 E SG ID VGS + G V C C C +G + C+ + R GF Sbjct: 75 ELSGVIDKVGSTAEKMGFKVGQKVVANYAKYCGCCENCREGKVNLCSNMGY----RMNGF 130 Query: 118 AEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAI 177 +EY V +F +P D ++D A +EP+TV L + A+ K+V I+GAG +G++ + Sbjct: 131 SEYAVYHMSQIFPIPDDADLKDYALVEPLTVALSSAEQAKISYGKSVAIMGAGGLGMMLV 190 Query: 178 QCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETA 237 Q A GA ++T DI EKL LA GA NS+E + L R+ +LE Sbjct: 191 QLARLAGASTITVFDIVPEKLELALENGADYALNSAEEGVAERAIELAGGRY-DCVLEGT 249 Query: 238 GVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQ 297 G +L +++ +D L + + + G Sbjct: 250 GATAAAKLGLQLLARDGDAVYFAMYGKDPILPVNLQSDLYWDQKHIHGMIQG------AW 303 Query: 298 EWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVL 343 ++ + R++ ++ +I + ++ QA D+ V+ Sbjct: 304 QFPKSIRMIP--RMDFSKIIQKEHTLTNYKQAFEDLYSKKYAKIVI 347 >4EEZ-A nrPDB Length = 348 Score = 250 bits (639), Expect = 6e-67, Method: Composition-based stats. Identities = 83/348 (23%), Positives = 140/348 (40%), Gaps = 16/348 (4%) Query: 1 MKSVV--NDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLG 58 MK+ V ++ DG + E + IK +E + + G+C +DL + + LG Sbjct: 1 MKAAVVRHNPDGYADLVEKELRAIK-PNEALLDMEYCGVCHTDLHVAAGDFGNKAGTVLG 59 Query: 59 HEFSGYIDAVGSGVDDLHPGDAVACVPLL-PCFTCPECLKGFYSQCAKYDFIGSRRDGGF 117 HE G + +G+ V L GD V+ C C C+ G + C + G DGG Sbjct: 60 HEGIGIVKEIGADVSSLQVGDRVSVAWFFEGCGHCEYCVSGNETFCREVKNAGYSVDGGM 119 Query: 118 AEYIVVKRKNVFALPTDM-PIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLA 176 AE +V +P + PIE + A ++ +I GAG +G LA Sbjct: 120 AEEAIVVADYAVKVPDGLDPIEASSITCAGVTTYKAIKVSGVKPGDWQVIFGAGGLGNLA 179 Query: 177 IQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILET 236 IQ A + V A+DI+ +KL LAK GA T NS +++ + Q + Sbjct: 180 IQYAKNVFGAKVIAVDINQDKLNLAKKIGADVTINSGDVNPVDEIKKITGGLGVQSAIVC 239 Query: 237 AGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPG 296 A E AV P ++ V + ++ L+ T ++ + V GS + Sbjct: 240 AVARIAFEQAVASLKPMGKMVAVAVPNTEMTLSVPT---VVFDGVEVAGSLVGTR----- 291 Query: 297 QEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 + A + E K+ I E + ++ + G++++ Sbjct: 292 LDLAEAFQFGAEGKVKP---IVATRKLEEINDIIDEMKAGKIEGRMVI 336 >6N7L-A nrPDB Length = 353 Score = 248 bits (634), Expect = 2e-66, Method: Composition-based stats. Identities = 84/349 (24%), Positives = 143/349 (40%), Gaps = 21/349 (6%) Query: 1 MKSVVNDTDG-IVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYY--PITL 57 MK+ V G +++ E + E + EV VK+ + G+C +DL + + P+ Sbjct: 14 MKAAVVQGYGEPLKIQEVPVRE-PGRYEVLVKVMACGVCHTDLHAVDGDWPAKPKMPLIP 72 Query: 58 GHEFSGYIDAVGSGVDDLHPGDAVACVPLLP-CFTCPECLKGFYSQCAKYDFIGSRRDGG 116 GHE G + A G + GDAV L C C C+ G+ + C G DGG Sbjct: 73 GHEGVGIVVACGPDAM-VKEGDAVGVPWLYSACGCCDYCITGWETLCEAQQNGGYSVDGG 131 Query: 117 FAEYIVVKRKNVFALPTDMP-IEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLL 175 FAEY++ + V L +++ +E + + + V I G G +G + Sbjct: 132 FAEYVIADSRYVGHLKSNVNFLEIAPILCAGVTVYKGLKETETKPGEWVAISGIGGLGHV 191 Query: 176 AIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILE 235 A+Q A A+G V AID++ +KL LAK GA T N+ +E+ L Sbjct: 192 AVQYAKAMGMH-VAAIDVADDKLELAKKLGADLTVNAKTTDPGTYLH--KEVGGMHGALI 248 Query: 236 TAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWP 295 TA P + +++ +AL G L + + K +TV GS + Sbjct: 249 TAVSPIAFKQGIDVLRRKGTIALNGLPPGSFEL---PIFETVLKRITVRGSIVGTR---- 301 Query: 296 GQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 ++ + A E ++ + E + + + G+++L Sbjct: 302 -KDLQEALDFANEGL--VKATVT-SAKLEDINDVFDKMKKGQIDGRIVL 346 >1CDO-A nrPDB Length = 374 Score = 245 bits (626), Expect = 2e-65, Method: Composition-based stats. Identities = 81/370 (21%), Positives = 155/370 (41%), Gaps = 37/370 (10%) Query: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNG-AHYYPITLGHEF 61 +V + + + + E + ++ H +E+R+KI ++G+C +DL +F+ +P+ LGHE Sbjct: 12 AVAWEANKPLVIEEIEV-DVPHANEIRIKIIATGVCHTDLYHLFEGKHKDGFPVVLGHEG 70 Query: 62 SGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAK---------------- 105 +G +++VG GV + PG+ V + + C C C +QC K Sbjct: 71 AGIVESVGPGVTEFQPGEKVIPLFISQCGECRFCQSPKTNQCVKGWANESPDVMSPKETR 130 Query: 106 --------YDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAFI-EPITVGLH-AFHL 155 F+G+ F++Y VV + V + P++ + ++ G A + Sbjct: 131 FTCKGRKVLQFLGTST---FSQYTVVNQIAVAKIDPSAPLDTVCLLGCGVSTGFGAAVNT 187 Query: 156 AQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEM 215 A+ + G G +GL A+ + GAK + A+D++ +K AK FGA N ++ Sbjct: 188 AKVEPGSTCAVFGLGAVGLAAVMGCHSAGAKRIIAVDLNPDKFEKAKVFGATDFVNPNDH 247 Query: 216 SAPQMQSVLREL-RFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFG 274 S P Q + + LE G + A+E ++++ + + Sbjct: 248 SEPISQVLSKMTNGGVDFSLECVGNVGVMRNALESCLKGWGVSVLVGWTDLHDVATRPIQ 307 Query: 275 KILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIA 334 I + GS G + ++K+ L+ I HR ES A+ D+ Sbjct: 308 LIAGRTW--KGSMFGGFKGKDG--VPKMVKAYLDKKVKLDEFITHRMPLESVNDAI-DLM 362 Query: 335 RNAMPGKVLL 344 ++ + +L Sbjct: 363 KHGKCIRTVL 372 >6DKH-A nrPDB Length = 346 Score = 244 bits (624), Expect = 3e-65, Method: Composition-based stats. Identities = 92/326 (28%), Positives = 133/326 (40%), Gaps = 23/326 (7%) Query: 29 RVKIASSGLCGSDLPRIF----KNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACV 84 V+I G+CGSDL N P+ LGHE G + + S +LH G VA Sbjct: 34 LVQITRGGICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKV--IHSDSSELHEGQTVAIN 91 Query: 85 PLLPCFTCPECLKGFYSQCAKYDFIGS-----RRDGGFAEYIVVKRKNVFALPTDMPIED 139 P PC C C++ +QC F GS DGGF Y +V+ P + Sbjct: 92 PSKPCGHCKYCIEHNENQCTDMRFFGSAMYFPHVDGGFTRYKMVETSQCVPYPAKADEKV 151 Query: 140 GAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLA 199 AF EP+ V +HA H A + K V I G G IG L + LGA + D+S L+ Sbjct: 152 MAFAEPLAVAIHAAHQAGELQGKRVFISGVGPIGCLIVSAVKTLGAAEIVCADVSPRSLS 211 Query: 200 LAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALV 259 L K GA N M E + + E +G P +V +E+ + V Sbjct: 212 LGKEMGADVLVNPQNDD---MDHWKAEKGYFDVSFEVSGHPSSVNTCLEVTRARGVMVQV 268 Query: 260 GTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAH 319 G + ++ KE+++ GS+ S E+ TA L ++ PL++ Sbjct: 269 GMGGA---MAEFPMMTLIGKEISLRGSFRFTS------EFNTAVSWLANGVINPLPLLSA 319 Query: 320 RGSFESFAQAVRDIARNAMPGKVLLI 345 F +A+R KV L+ Sbjct: 320 EYPFTDLEEALRFAGDKTQAAKVQLV 345 >3IP1-A nrPDB Length = 404 Score = 244 bits (623), Expect = 5e-65, Method: Composition-based stats. Identities = 92/362 (25%), Positives = 148/362 (40%), Gaps = 36/362 (9%) Query: 12 VRVAESVIPEIKHQDEVRVKIASSGLCGSDLPR--------IFKNGAHYYPITLGHEFSG 63 VRV E P I+ E+ +K+ + G+CGSD+ I G +P+TLGHEFSG Sbjct: 42 VRVEEVPEPRIEKPTEIIIKVKACGICGSDVHMAQTDEEGYILYPGLTGFPVTLGHEFSG 101 Query: 64 YIDAVGSGV------DDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGF 117 + G G+ V +L C C C +GF + C + +G DG F Sbjct: 102 VVVEAGPEAINRRTNKRFEIGEPVCAEEMLWCGHCRPCAEGFPNHCENLNELGFNVDGAF 161 Query: 118 AEYIVVKRKNVFALPT-------DMPIEDGAFIEPITVGLHAF--HLAQGCENKNVIIIG 168 AEY+ V K ++L D G+ +EP +V +A NV+I+G Sbjct: 162 AEYVKVDAKYAWSLRELEGVYEGDRLFLAGSLVEPTSVAYNAVIVRGGGIRPGDNVVILG 221 Query: 169 AGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELR 228 G IGL A+ GA V + S + LAK GA + ++ + + Sbjct: 222 GGPIGLAAVAILKHAGASKVILSEPSEVRRNLAKELGADHVIDPTKENFVEAVLDYTNGL 281 Query: 229 FNQLILETAGVPQTV-----ELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTV 283 +L LE GVPQ V E+ G +A +A+V + LT F + + Sbjct: 282 GAKLFLEATGVPQLVWPQIEEVIWRARGINATVAIVARADAKIPLTGEVFQ---VRRAQI 338 Query: 284 IGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVL 343 +GS + + L+ + + +I+ S E + ++ + + KV Sbjct: 339 VGSQGHSGH----GTFPRVISLMASG-MDMTKIISKTVSMEEIPEYIKRLQTDKSLVKVT 393 Query: 344 LI 345 ++ Sbjct: 394 ML 395 >5K1S-A nrPDB Length = 362 Score = 243 bits (620), Expect = 1e-64, Method: Composition-based stats. Identities = 80/354 (22%), Positives = 143/354 (40%), Gaps = 20/354 (5%) Query: 1 MKSVVNDTDG---IVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGA-HYYPIT 56 MK+VV + G +++ +P + EV +++ + G+C D+ N P Sbjct: 18 MKAVVLRSFGEAGNLKMETMPMPR-PGRGEVLLRVHACGVCYHDVINRRGNLPRTSVPAI 76 Query: 57 LGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQC-AKYDFIGSRRDG 115 LGHE +G + VG GD A + + C C C G S C F G G Sbjct: 77 LGHEAAGEVIEVGPDTPGWKTGDRAATLQRMSCGDCALCRSGRNSLCKTDNRFFGEELPG 136 Query: 116 GFAEYIVVKRKNVFALPTDMPIEDGAFIEPIT-VGLHAFHL-AQGCENKNVIIIGA-GTI 172 G+A+++V + +P +P + A + T +H + + V+I GA G + Sbjct: 137 GYAQFMVAPVGGLGRVPASLPWNEAATVCCTTGTAVHTVRTRGKVRAGETVLITGASGGV 196 Query: 173 GLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQL 232 GL ++Q A GA V A+ S K+ K GA + S + + + Sbjct: 197 GLSSVQLARLDGA-RVIAVTSSEAKVQALKEAGADEVIVSRGLDFASDVRKRTQGAGVDV 255 Query: 233 ILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSS 292 +E G T + ++ P ++ +VG L + G ++ KEL ++G++ Sbjct: 256 AVEIVGS-ATFDQTLKSMAPGGRVVVVGNLESG--MVQLNPGLVIVKELEILGAYATTQ- 311 Query: 293 PWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP 346 E + A RL + + A+A + + G+++L+P Sbjct: 312 ----AELDEALRLTATGG--VRQFVTDAVPLAEAAKAHFRLENREVAGRLVLVP 359 >4DLA-A nrPDB Length = 396 Score = 242 bits (619), Expect = 1e-64, Method: Composition-based stats. Identities = 81/372 (21%), Positives = 144/372 (38%), Gaps = 39/372 (10%) Query: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIF-KNGAHYYPITLGHEF 61 +V + + + + + + EVRVK+ + LC +D K+ +P LGHE Sbjct: 30 AVAWEPNKPLVIEDVQV-APPQAGEVRVKVLYTALCHTDAYTWSGKDPEGLFPCVLGHEA 88 Query: 62 SGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAK---------------- 105 +G +++VG GV ++ PGD V C C C G + C K Sbjct: 89 AGIVESVGEGVTEVQPGDHVIPCYQAECRECKFCKSGKTNLCGKVRAATGVGVMMNDRKS 148 Query: 106 ---------YDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAFI-EPITVGLHA-FH 154 Y F+G+ F++Y VV +V + P+E + + GL A ++ Sbjct: 149 RFSINGKPIYHFMGTST---FSQYTVVHDVSVAKIDPVAPLEKVCLLGCGVPTGLGAVWN 205 Query: 155 LAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSE 214 A+ V + G GT+GL + A A GA + IDI S+K AK+FG + N E Sbjct: 206 TAKVEPGSIVAVFGLGTVGLAVAEGAKAAGASRIIGIDIDSKKFDRAKNFGVTEFINPKE 265 Query: 215 MSAPQMQSVLR-ELRFNQLILETAGVPQTVELAVEIAGPH-AQLALVGTLHQDLHLTSAT 272 P Q ++ E G + A+E +VG +++ Sbjct: 266 HEQPIQQVIVDLTDGGVDYSFECIGNVSVMRSALECCHKGWGTSVIVGVAASGQEISTRP 325 Query: 273 FGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRD 332 F + + G+ + + ++++ ++ I H + +A D Sbjct: 326 FQLVTGRVW--KGTAFGG--FKSRSQVPSLVDKYLKKEIKVDEYITHNMTLADINKAF-D 380 Query: 333 IARNAMPGKVLL 344 + + +V+L Sbjct: 381 LMHDGDCLRVVL 392 >3M6I-A nrPDB Length = 363 Score = 242 bits (617), Expect = 2e-64, Method: Composition-based stats. Identities = 89/342 (26%), Positives = 141/342 (41%), Gaps = 20/342 (5%) Query: 13 RVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPIT-----LGHEFSGYIDA 67 + E + EV V + S+G+CGSD+ +K+G I LGHE +G + A Sbjct: 28 SLESVQKGEELKEGEVTVAVRSTGICGSDVH-FWKHGCIGPMIVECDHVLGHESAGEVIA 86 Query: 68 VGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKN 127 V V + GD VA P + C C CL G Y+ C + DF+ + G V Sbjct: 87 VHPSVKSIKVGDRVAIEPQVICNACEPCLTGRYNGCERVDFLSTPPVPGLLRRYVNHPAV 146 Query: 128 VFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKS 187 +M E+GA +EP++V L A V+I GAG IGL+ + CA A GA Sbjct: 147 WCHKIGNMSYENGAMLEPLSVALAGLQRAGVRLGDPVLICGAGPIGLITMLCAKAAGACP 206 Query: 188 VTAIDISSEKLALAKSFGAMQT-FNSSEMSAPQMQSVLRELRFN---QLILETAGVPQTV 243 + DI +L AK +SA + + E + LE GV ++ Sbjct: 207 LVITDIDEGRLKFAKEICPEVVTHKVERLSAEESAKKIVESFGGIEPAVALECTGVESSI 266 Query: 244 ELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETAS 303 A+ ++ ++G ++ + F + +E+ + + Y + WP A Sbjct: 267 AAAIWAVKFGGKVFVIGVGKNEIQI---PFMRASVREVDLQFQY-RYCNTWP-----RAI 317 Query: 304 RLLTERKLSLEPLIAHRGSFESFAQAVRDIAR-NAMPGKVLL 344 RL+ + L L+ HR E +A + KV + Sbjct: 318 RLVENGLVDLTRLVTHRFPLEDALKAFETASDPKTGAIKVQI 359 >4JJI-A nrPDB Length = 378 Score = 241 bits (616), Expect = 3e-64, Method: Composition-based stats. Identities = 81/369 (21%), Positives = 137/369 (37%), Gaps = 46/369 (12%) Query: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIF-KNGAHYYPITLGHEF 61 +V + + + + + + EVR+KI + LC +D K+ +P LGHE Sbjct: 12 AVAYEPNKPLVIEDVQV-APPQAGEVRIKILYTALCHTDAYTWSGKDPEGLFPCILGHEA 70 Query: 62 SGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAK---------------- 105 +G +++VG GV ++ GD V C C C G + C K Sbjct: 71 AGIVESVGEGVTEVQAGDHVIPCYQAECRECKFCKSGKTNLCGKVRSATGVGIMMNDRKS 130 Query: 106 ---------YDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAFI-EPITVGLHA-FH 154 Y F+G+ F++Y VV +V + P++ + + GL A ++ Sbjct: 131 RFSVNGKPIYHFMGTST---FSQYTVVHDVSVAKIDPTAPLDKVCLLGCGVPTGLGAVWN 187 Query: 155 LAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSE 214 A+ NV I G GT+GL + A GA + IDI S+K AK FG + N + Sbjct: 188 TAKVEPGSNVAIFGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETAKKFGVNEFVNPKD 247 Query: 215 MSAPQMQSVLREL--RFNQLILETAGVPQTVELAVEIAGPH-AQLALVGTLHQDLHLTSA 271 P +Q V+ +L E G + A+E +VG +++ Sbjct: 248 HDKP-IQEVIVDLTDGGVDYSFECIGNVSVMRAALECCHKGWGTSVIVGVAASGQEISTR 306 Query: 272 TFGKILR---KELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQ 328 F + K G PW +++ ++ I H + + Sbjct: 307 PFQLVTGRVWKGTAFGGFKSRTQVPW-------LVEKYMNKEIKVDEYITHNLTLGEINK 359 Query: 329 AVRDIARNA 337 A + Sbjct: 360 AFDLLHEGT 368 >1F8F-A nrPDB Length = 371 Score = 239 bits (609), Expect = 2e-63, Method: Composition-based stats. Identities = 84/344 (24%), Positives = 138/344 (40%), Gaps = 37/344 (10%) Query: 21 EIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDA 80 DEV VK+ ++G+C +DL + P LGHE SG I+A+G V +L GD Sbjct: 27 RQPQGDEVLVKVVATGMCHTDLIVRDQKYPVPLPAVLGHEGSGIIEAIGPNVTELQVGDH 86 Query: 81 VACVPLLPCFTCPECLKGFYSQCAKY---DFIGSRRDGG--------------------F 117 V + C C +C G + C+++ +F G+ +G F Sbjct: 87 V-VLSYGYCGKCTQCNTGNPAYCSEFFGRNFSGADSEGNHALCTHDQGVVNDHFFAQSSF 145 Query: 118 AEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHA-----FHLAQGCENKNVIIIGAGTI 172 A Y + + N + D+PIE + P+ G+ + + + + GAG + Sbjct: 146 ATYALSRENNTVKVTKDVPIE---LLGPLGCGIQTGAGACINALKVTPASSFVTWGAGAV 202 Query: 173 GLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQL 232 GL A+ A GA + A+DI +L LAK GA NS + + Sbjct: 203 GLSALLAAKVCGASIIIAVDIVESRLELAKQLGATHVINSKTQDPVAAIKEITDG-GVNF 261 Query: 233 ILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSS 292 LE+ G P+ ++ V+ G ++A+VG +L T++G S Sbjct: 262 ALESTGSPEILKQGVDALGILGKIAVVGAPQLGTTA-QFDVNDLLLGGKTILGVVEGSGS 320 Query: 293 PWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARN 336 P + RL + K + L+ +F+ QA D + Sbjct: 321 --PKKFIPELVRLYQQGKFPFDQLVKF-YAFDEINQAAIDSRKG 361 >1YKF-A nrPDB Length = 352 Score = 235 bits (599), Expect = 3e-62, Method: Composition-based stats. Identities = 76/346 (21%), Positives = 126/346 (36%), Gaps = 12/346 (3%) Query: 1 MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNG-AHYYPITLGH 59 MK + G V E P + V+ + C SD+ +F+ + + LGH Sbjct: 1 MKGFAMLSIGKVGWIEKEKP-APGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGH 59 Query: 60 EFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDF---IGSRRDGG 116 E G + VGS V D PGD V + P + E +G++ + +DG Sbjct: 60 EAVGEVVEVGSEVKDFKPGDRVVVPAITPDWRTSEVQRGYHQHSGGMLAGWKFSNVKDGV 119 Query: 117 FAEYIVVKRK--NVFALPTDMPIEDGAFI-EPITVGLHAFHLAQGCENKNVIIIGAGTIG 173 F E+ V N+ LP ++P+E I + +T G H LA V ++G G +G Sbjct: 120 FGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGAELADIELGATVAVLGIGPVG 179 Query: 174 LLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLI 233 L+A+ A GA + A+ + AK +GA N + L E + Sbjct: 180 LMAVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKDGPIESQIMNLTEGKGVDAA 239 Query: 234 LETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSP 293 + G + AV+I P +A V + L + P Sbjct: 240 IIAGGNADIMATAVKIVKPGGTIANVNYFGEGEVLPVPRLEWGCGMA---HKTIKGGLCP 296 Query: 294 WPGQEWETASRLLTERKLSLEPLIAHRG-SFESFAQAVRDIARNAM 338 E L+ +++ L+ H F++ +A + Sbjct: 297 GGRLRMERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKDKPK 342 >1P0F-A nrPDB Length = 373 Score = 234 bits (598), Expect = 3e-62, Method: Composition-based stats. Identities = 73/367 (19%), Positives = 140/367 (38%), Gaps = 31/367 (8%) Query: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFS 62 +V + + + + EVR+KI +SG+CGSD + + +P+ LGHE Sbjct: 13 AVAWEPHKPLSLETITV-APPKAHEVRIKILASGICGSDSSVLKEIIPSKFPVILGHEAV 71 Query: 63 GYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIG------------ 110 G ++++G+GV + PGD V + + C +C C + C K D Sbjct: 72 GVVESIGAGVTCVKPGDKVIPLFVPQCGSCRACKSSNSNFCEKNDMGAKTGLMADMTSRF 131 Query: 111 -------SRRDG--GFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLH-AFHLAQGCE 160 G F EY VV V + P+E G A + A+ Sbjct: 132 TCRGKPIYNLMGTSTFTEYTVVADIAVAKIDPKAPLESCLIGCGFATGYGAAVNTAKVTP 191 Query: 161 NKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQM 220 + G G +G AI A GA + + +K A GA + N + P Sbjct: 192 GSTCAVFGLGGVGFSAIVGCKAAGASRIIGVGTHKDKFPKAIELGATECLNPKDYDKPIY 251 Query: 221 QSVLREL-RFNQLILETAGVPQTVELAVEIAGPHAQLALV-GTLHQDLHLTSATFGKILR 278 + + + +E AG +T+ A++ + + +V G + L + Sbjct: 252 EVICEKTNGGVDYAVECAGRIETMMNALQSTYCGSGVTVVLGLASPNERLPLDPLLLLTG 311 Query: 279 KELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAM 338 + ++ GS + G+E ++K+++ L++ + + + +A + + Sbjct: 312 R--SLKGSVFGG---FKGEEVSRLVDDYMKKKINVNFLVSTKLTLDQINKAFE-LLSSGQ 365 Query: 339 PGKVLLI 345 + ++I Sbjct: 366 GVRSIMI 372 >3FPC-A nrPDB Length = 352 Score = 234 bits (596), Expect = 6e-62, Method: Composition-based stats. Identities = 79/349 (22%), Positives = 135/349 (38%), Gaps = 18/349 (5%) Query: 1 MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNG-AHYYPITLGH 59 MK + G V E P + V+ + C SD+ +F+ + + LGH Sbjct: 1 MKGFAMLSIGKVGWIEKEKP-APGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGH 59 Query: 60 EFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDF---IGSRRDGG 116 E G + VGS V D PGD V + P + E +G++ + +DG Sbjct: 60 EAVGEVVEVGSEVKDFKPGDRVVVPAITPDWRTSEVQRGYHQHSGGMLAGWKFSNVKDGV 119 Query: 117 FAEYIVVKRK--NVFALPTDMPIEDGAFI-EPITVGLHAFHLAQGCENKNVIIIGAGTIG 173 F E+ V N+ LP ++P+E I + +T G H LA V +IG G +G Sbjct: 120 FGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGAELANIKLGDTVCVIGIGPVG 179 Query: 174 LLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLI 233 L+++ A LGA + A+ +A +GA N + + + + Sbjct: 180 LMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIINYKNGDIVEQILKATDGKGVDKV 239 Query: 234 LETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTV-IGSWMNYSS 292 + G T AV++ P + + V L + ++ I R E V +G + Sbjct: 240 VIAGGDVHTFAQAVKMIKPGSDIGNVNYLGEGDNI------DIPRSEWGVGMGHKHIHGG 293 Query: 293 PWPGQ--EWETASRLLTERKLSLEPLIAHRG-SFESFAQAVRDIARNAM 338 PG E L+ +++ L+ H F++ +A + Sbjct: 294 LCPGGRLRMERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKDKPK 342 >3FPL-A nrPDB Length = 351 Score = 232 bits (592), Expect = 2e-61, Method: Composition-based stats. Identities = 80/354 (22%), Positives = 126/354 (35%), Gaps = 13/354 (3%) Query: 1 MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNG-AHYYPITLGH 59 MK + E P + + V+ + C SD+ +F+ + LGH Sbjct: 1 MKGFAMLGINKLGWIEKERP-VAGSYDAIVRPLAVSPCTSDIHTVFEGALGDRKNMILGH 59 Query: 60 EFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDF---IGSRRDGG 116 E G + VGS V D PGD V P + E GF + +DG Sbjct: 60 EAVGEVVEVGSEVKDFKPGDRVIVPCTTPDWRSLEVQAGFQQHSNGMLAGWKFSNFKDGV 119 Query: 117 FAEYIVVKRK--NVFALPTDMPIEDGAFI-EPITVGLHAFHLAQGCENKNVIIIGAGTIG 173 F EY V N+ LP DMP+E+ I + +T G H LA V ++G G +G Sbjct: 120 FGEYFHVNDADMNLAILPKDMPLENAVMITDMMTTGFHGAELADIELGATVAVLGIGPVG 179 Query: 174 LLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLI 233 L+A+ A GA + A+ + AK +GA N + L E + Sbjct: 180 LMAVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKDGPIESQIMNLTEGKGVDAA 239 Query: 234 LETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSP 293 + G + AV+I P +A V + L + P Sbjct: 240 IIAGGNADIMATAVKIVKPGGTIANVNYFGEGEVLPVPRLEWGCGMA---HKTIKGGLCP 296 Query: 294 WPGQEWETASRLLTERKLSLEPLIAHRG-SFESFAQAVRDIARNAMP-GKVLLI 345 E ++ ++ L L+ H F+ +A+ + K ++I Sbjct: 297 GGRLRAEMLRDMVVYNRVDLSKLVTHVYHGFDHIEEALLLMKDKPKDLIKAVVI 350 >3FSR-A nrPDB Length = 352 Score = 232 bits (592), Expect = 2e-61, Method: Composition-based stats. Identities = 73/346 (21%), Positives = 125/346 (36%), Gaps = 12/346 (3%) Query: 1 MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNG-AHYYPITLGH 59 MK + G V E P + V+ + C SD+ +F+ + + LGH Sbjct: 1 MKGFAMLSIGKVGWIEKEKP-APGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGH 59 Query: 60 EFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDF---IGSRRDGG 116 E G + VGS V D PGD V + P + E +G++ + +DG Sbjct: 60 EAVGEVVEVGSEVKDFKPGDRVVVPAITPDWRTSEVQRGYHQHSGGMLAGWKFSNVKDGV 119 Query: 117 FAEYIVVKRK--NVFALPTDMPIEDGAFI-EPITVGLHAFHLAQGCENKNVIIIGAGTIG 173 F E+ V N+ LP ++P+E I + +T G H LA +V++IG G +G Sbjct: 120 FGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGAELADIQMGSSVVVIGIGAVG 179 Query: 174 LLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLI 233 L+ I A GA + + + AK +GA N L + + Sbjct: 180 LMGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKNGHIVDQVMKLTNGKGVDRV 239 Query: 234 LETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSP 293 + G +T+ AV + P ++ + L + P Sbjct: 240 IMAGGGSETLSQAVSMVKPGGIISNINYHGSGDALLIPRVEWGCGMA---HKTIKGGLCP 296 Query: 294 WPGQEWETASRLLTERKLSLEPLIAHRG-SFESFAQAVRDIARNAM 338 E L+ +++ L+ H F++ +A + Sbjct: 297 GGRLRMERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKDKPK 342 >1KEV-A nrPDB Length = 351 Score = 229 bits (585), Expect = 1e-60, Method: Composition-based stats. Identities = 77/354 (21%), Positives = 125/354 (35%), Gaps = 13/354 (3%) Query: 1 MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNG-AHYYPITLGH 59 MK + E P + + V+ + C SD+ +F+ + LGH Sbjct: 1 MKGFAMLGINKLGWIEKERP-VAGSYDAIVRPLAVSPCTSDIHTVFEGALGDRKNMILGH 59 Query: 60 EFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDF---IGSRRDGG 116 E G + VGS V D PGD V P + E GF + +DG Sbjct: 60 EAVGEVVEVGSEVKDFKPGDRVIVPCTTPDWRSLEVQAGFQQHSNGMLAGWKFSNFKDGV 119 Query: 117 FAEYIVVKRK--NVFALPTDMPIEDGAFI-EPITVGLHAFHLAQGCENKNVIIIGAGTIG 173 F EY V N+ LP DMP+E+ I + +T G H LA +V++IG G +G Sbjct: 120 FGEYFHVNDADMNLAILPKDMPLENAVMITDMMTTGFHGAELADIQMGSSVVVIGIGAVG 179 Query: 174 LLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLI 233 L+ I A GA + + + AK +GA N L + + Sbjct: 180 LMGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKNGHIVDQVMKLTNGKGVDRV 239 Query: 234 LETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSP 293 + G +T+ AV + P ++ + L + P Sbjct: 240 IMAGGGSETLSQAVSMVKPGGIISNINYHGSGDALLIPRVEWGCGMA---HKTIKGGLCP 296 Query: 294 WPGQEWETASRLLTERKLSLEPLIAHRG-SFESFAQAVRDIARNAMP-GKVLLI 345 E ++ ++ L L+ H F+ +A+ + K ++I Sbjct: 297 GGRLRAEMLRDMVVYNRVDLSKLVTHVYHGFDHIEEALLLMKDKPKDLIKAVVI 350 >2OUI-A nrPDB Length = 360 Score = 229 bits (584), Expect = 1e-60, Method: Composition-based stats. Identities = 83/349 (23%), Positives = 132/349 (37%), Gaps = 18/349 (5%) Query: 1 MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNG-AHYYPITLGH 59 MK + G + E IPE + V+ + C SD ++ + + LGH Sbjct: 1 MKGLAMLGIGRIGWIEKKIPEC-GPLDALVRPLALAPCTSDTHTVWAGAIGDRHDMILGH 59 Query: 60 EFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDF---IGSRRDGG 116 E G I VGS V L GD V + P + E +G+ + +DG Sbjct: 60 EAVGQIVKVGSLVKRLKVGDKVIVPAITPDWGEEESQRGYPMHSGGMLGGWKFSNFKDGV 119 Query: 117 FAEYIVVKRK--NVFALPTDMPIEDGAFI-EPITVGLHAFHLAQGCENKNVIIIGAGTIG 173 F+E V N+ LP D+ ED + + +T G H LA V +IG G +G Sbjct: 120 FSEVFHVNEADANLALLPRDIKPEDAVMLSDMVTTGFHGAELANIKLGDTVCVIGIGPVG 179 Query: 174 LLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLI 233 L+++ A LGA + A+ +A +GA N + + + + Sbjct: 180 LMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIINYKNGDIVEQILKATDGKGVDKV 239 Query: 234 LETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTV-IGSWMNYSS 292 + G T AV++ P + + V L + ++ I R E V +G + Sbjct: 240 VIAGGDVHTFAQAVKMIKPGSDIGNVNYLGEGDNI------PIPRSEWGVGMGHKHIHGG 293 Query: 293 PWPGQ--EWETASRLLTERKLSLEPLIAHRG-SFESFAQAVRDIARNAM 338 PG E + L++ KL LI HR E A+ + Sbjct: 294 LTPGGRVRMEKLASLISTGKLDTSKLITHRFEGLEKVEDALMLMKNKPA 342 >5TNX-A nrPDB Length = 383 Score = 226 bits (576), Expect = 1e-59, Method: Composition-based stats. Identities = 79/340 (23%), Positives = 127/340 (37%), Gaps = 37/340 (10%) Query: 21 EIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDA 80 DEV V++ ++GLC +DL + P LGHE +G ++AVG V L GD Sbjct: 38 RAPRGDEVLVRVVATGLCHTDLIVRDQYYPVPLPAVLGHEGAGVVEAVGPNVKTLAAGDH 97 Query: 81 VACVPLLPCFTCPECLKGFYSQCAKY---DFIGSRRDG--------------------GF 117 V + C C C G + C ++ +F G+ DG F Sbjct: 98 V-VLTYGACGHCASCAGGHGAYCRQFFALNFGGADADGQTALRDAAGEPLHDHFFAQSSF 156 Query: 118 AEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHA-----FHLAQGCENKNVIIIGAGTI 172 A Y + + N +P + P+E + P+ G+ + + GAG + Sbjct: 157 ASYALARENNAIKVPKEAPLE---LLGPLGCGIQTGAGAVINSLAVRTGSSFASFGAGAV 213 Query: 173 GLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQL 232 G+ A+ A GA ++ A+DI +LALA GA NS E+ + Sbjct: 214 GMSAVMAARIAGATTIIAVDIVPSRLALALELGATHAINSKEVDVVDAIREIT-GGGVDY 272 Query: 233 ILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSS 292 LE+ G+P + ++ G + +VG +L T+ G S Sbjct: 273 ALESTGLPAVLSQGIDALGSRGTMGVVGAPKLGTKAEF-DVNSLLLGGHTIRGIVEGDSV 331 Query: 293 PWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRD 332 P +L + + + L+ E QA D Sbjct: 332 --PQTFIPQLVQLHLQGRFPFDRLVKF-YPLEQINQAAAD 368 >4GKV-A nrPDB Length = 336 Score = 220 bits (560), Expect = 8e-58, Method: Composition-based stats. Identities = 79/346 (22%), Positives = 131/346 (37%), Gaps = 16/346 (4%) Query: 1 MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHE 60 MK+ V D V V + +KH E +K+ G+C +DL + + LGHE Sbjct: 1 MKAAVVTKDHHVDVTYKTLRSLKH-GEALLKMECCGVCHTDLHVKNGDFGDKTGVILGHE 59 Query: 61 FSGYIDAVGSGVDDLHPGDAVACVPLL-PCFTCPECLKGFYSQCAKYDFIGSRRDGGFAE 119 G + VG GV L PGD + C C C G + C G DGG AE Sbjct: 60 GIGVVAEVGPGVTSLKPGDRASVAWFYEGCGHCEYCNSGNETLCRSVKNAGYSVDGGMAE 119 Query: 120 YIVVKRKNVFALPTDMPIEDGAFI-EPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQ 178 +V +P + + I A L++ + + I G G +G LA+Q Sbjct: 120 ECIVVADYAVKVPDGLDSAAASSITCAGVTTYKAVKLSKIRPGQWIAIYGLGGLGNLALQ 179 Query: 179 CAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAG 238 A + V AID++ E+L LA GA NS A ++ + TA Sbjct: 180 YAKNVFNAKVIAIDVNDEQLKLATEMGADLAINSHTEDAAKIVQEKT--GGAHAAVVTAV 237 Query: 239 VPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQE 298 AV+ ++ VG + + L +++ + V+GS + Q+ Sbjct: 238 AKAAFNSAVDAVRAGGRVVAVGLPPESMSLDIP---RLVLDGIEVVGSLVGTR-----QD 289 Query: 299 WETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 A + E K+ + + ++ + G++++ Sbjct: 290 LTEAFQFAAEGKVVPKVAL---RPLADINTIFTEMEEGKIRGRMVI 332 >6FG0-A nrPDB Length = 352 Score = 218 bits (556), Expect = 2e-57, Method: Composition-based stats. Identities = 80/358 (22%), Positives = 138/358 (38%), Gaps = 25/358 (6%) Query: 1 MKSVVNDTDGIVRVA-ESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHY---YPIT 56 MK+V G V + P E+ +K+ ++GLC SD+ + A Y P+T Sbjct: 1 MKAVQYTEIGSEPVVVDIPTP-TPGPGEILLKVTAAGLCHSDITVMDMPAAQYAGGLPLT 59 Query: 57 LGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFI-----GS 111 LGHE G + +G GV GDAVA C C C +G + C + + G Sbjct: 60 LGHEGVGTVAELGEGVTGFGVGDAVAVYGPWGCGACHACARGRENYCTRAADLGITPPGY 119 Query: 112 RRDGGFAEYIVVKRKNVFALPTDMPIEDGAFI-EPITVGLHAFHLAQG--CENKNVIIIG 168 G AEY++V D+ A + + HA ++IG Sbjct: 120 GSPGSMAEYMIVDSARHLVPIGDLDPVAAAPLTDAGLTPYHAISRVLPLLGPGSTAVVIG 179 Query: 169 AGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELR 228 G +G + IQ A+ A V A+D+ ++LALA+ GA S +A ++ L + Sbjct: 180 VGGLGHVGIQILRAVSAARVIAVDLDDDRLALAREVGADAAVKSGAGAADAIRE-LTGGQ 238 Query: 229 FNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWM 288 + + G T++ A ++ +++VG H H + G+ + Sbjct: 239 GATAVFDFVGAQSTIDTAQQVVAVDGHISVVGI-HAGAHAKVGFWMIP-------FGASV 290 Query: 289 NYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP 346 E L +L + + + A R + ++ G+ +++P Sbjct: 291 VTPYWGTRSELMEVVALARAGRLDIH---TETFTLDEGPAAYRRLREGSIRGRGVVVP 345 >2H6E-A nrPDB Length = 344 Score = 217 bits (554), Expect = 4e-57, Method: Composition-based stats. Identities = 78/354 (22%), Positives = 140/354 (39%), Gaps = 26/354 (7%) Query: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFK---NGAHYYPITLGH 59 +++ + + + IPE + + EV ++I +G+C +DL PI LGH Sbjct: 7 ALLKKFSEPLSIEDVNIPEPQGE-EVLIRIGGAGVCRTDLRVWKGVEAKQGFRLPIILGH 65 Query: 60 EFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAE 119 E +G I VG + GD V TC C +G ++ C G +GGF+E Sbjct: 66 ENAGTIVEVGELAK-VKKGDNVVVYATWGDLTCRYCREGKFNICKNQIIPGQTTNGGFSE 124 Query: 120 YIVV-KRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENK----NVIIIGAGTIGL 174 Y++V + + L + P+E + T + A A +K VI+ G G + + Sbjct: 125 YMLVKSSRWLVKLNSLSPVEAAPLADAGTTSMGAIRQALPFISKFAEPVVIVNGIGGLAV 184 Query: 175 LAIQCAVALGAKSVTAIDISSEK--LALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQL 232 IQ AL K++T + IS K A GA S A + + L + + Sbjct: 185 YTIQILKAL-MKNITIVGISRSKKHRDFALELGADYV--SEMKDAESLINKLTDGLGASI 241 Query: 233 ILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSS 292 ++ G +T ++ + LVG + + L + +K + S+ Sbjct: 242 AIDLVGTEETTYNLGKLLAQEGAIILVGMEGKRVSLEAFDTAVWNKK--------LLGSN 293 Query: 293 PWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP 346 + E RL K ++P I + +A ++ + G+ ++ P Sbjct: 294 YGSLNDLEDVVRLSESGK--IKPYIIKV-PLDDINKAFTNLDEGRVDGRQVITP 344 >3WLE-A nrPDB Length = 341 Score = 216 bits (549), Expect = 2e-56, Method: Composition-based stats. Identities = 85/346 (24%), Positives = 154/346 (44%), Gaps = 24/346 (6%) Query: 5 VNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFSGY 64 V + +++ + ++ +K+ + GLC SDL I++ +GHE +G Sbjct: 16 VFNKQSGLKLRNDLPVHKPKAGQLLLKVDAVGLCHSDLHVIYEGLDCGDNYVMGHEIAGT 75 Query: 65 IDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKY--DFIGSRRDGGFAEYIV 122 + AVG V + GD VACV C C C + C D+ G DGG+ +Y++ Sbjct: 76 VAAVGDDVINYKVGDRVACVGPNGCGGCKYCRGAIDNVCKNAFGDWFGLGYDGGYQQYLL 135 Query: 123 V-KRKNVFALPTDMPIE-DGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCA 180 V + +N+ +P ++ + A + + HA +AQ N+++IGAG +G AIQ A Sbjct: 136 VTRPRNLSRIPDNVSADVAAASTDAVLTPYHAIKMAQVSPTSNILLIGAGGLGGNAIQVA 195 Query: 181 VALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVP 240 A GAK VT +D E AK GA + + P+ S + V Sbjct: 196 KAFGAK-VTVLDKKKEARDQAKKLGADAVY----ETLPESISP----GSFSACFDFVSVQ 246 Query: 241 QTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWE 300 T ++ + P + VG +L S G + +E+ ++GS+ ++ + + Sbjct: 247 ATFDVCQKYVEPKGVIMPVGLGAPNL---SFNLGDLALREIRILGSFWGTTN-----DLD 298 Query: 301 TASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP 346 +L++E K ++P++ + + + + NA G+V+ P Sbjct: 299 DVLKLVSEGK--VKPVV-RSAKLKELPEYIEKLRNNAYEGRVVFNP 341 >5ENV-A nrPDB Length = 347 Score = 211 bits (537), Expect = 4e-55, Method: Composition-based stats. Identities = 66/346 (19%), Positives = 121/346 (34%), Gaps = 17/346 (4%) Query: 4 VVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGA--HYYPITLGHEF 61 + ++ G + + +P+ K +E+ + + SG+C +DL + P+ GHE Sbjct: 10 IFYESHGKLEYKDIPVPKPK-ANELLINVKYSGVCHTDLHAWHGDWPLPVKLPLVGGHEG 68 Query: 62 SGYIDAVGSGVDDLHPGDAVACVP-LLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEY 120 +G + +G V GD C C C G S C D G DG F +Y Sbjct: 69 AGVVVGMGENVKGWKIGDYAGIKWLNGSCMACEYCELGNESNCPHADLSGYTHDGSFQQY 128 Query: 121 IVVKRKNVFALPTDMPIEDGAFI-EPITVGLHAFHLAQGCENKNVIIIG-AGTIGLLAIQ 178 +P + A I A A V I G AG +G LA+Q Sbjct: 129 ATADAVQAAHIPQGTDLAQVAPILCAGITVYKALKSANLMAGHWVAISGAAGGLGSLAVQ 188 Query: 179 CAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAG 238 A A+G V ID K L +S G + ++ + ++ + Sbjct: 189 YAKAMG-YRVLGIDGGEGKEELFRSIGGEVFIDFTKEKDIVGAVLKATDGGAHGVINVSV 247 Query: 239 VPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQE 298 +E + + LVG S F +++ K ++++GS++ + Sbjct: 248 SEAAIEASTRYVRANGTTVLVGMP-AGAKCCSDVFNQVV-KSISIVGSYVGNR-----AD 300 Query: 299 WETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 A + P+ + + + + + G+ ++ Sbjct: 301 TREALDFFARGLVK-SPI--KVVGLSTLPEIYEKMEKGQIVGRYVV 343 >5YAT-A nrPDB Length = 350 Score = 211 bits (536), Expect = 4e-55, Method: Composition-based stats. Identities = 74/349 (21%), Positives = 135/349 (38%), Gaps = 18/349 (5%) Query: 2 KSVVNDTDG-IVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGA--HYYPITLG 58 K+V+ +T+G + + +P+ K +E+ + + SG+C +DL + + P+ G Sbjct: 10 KAVIFETNGGPLEYKDIPVPKPKS-NELLINVKYSGVCHTDLHAWKGDWPLDNKLPLVGG 68 Query: 59 HEFSGYIDAVGSGVDDLHPGDAVACVP-LLPCFTCPECLKGFYSQCAKYDFIGSRRDGGF 117 HE +G + A G V GD C C C++G S CAK D G DG F Sbjct: 69 HEGAGVVVAYGENVTGWEIGDYAGIKWLNGSCLNCEYCIQGAESSCAKADLSGFTHDGSF 128 Query: 118 AEYIVVKRKNVFALPTDMPI-EDGAFIEPITVGLHAFHLAQGCENKNVII-IGAGTIGLL 175 +Y +P + + E + A A + V I G +G L Sbjct: 129 QQYATADATQAARIPKEADLAEVAPILCAGITVYKALKTADLRIGQWVAISGAGGGLGSL 188 Query: 176 AIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILE 235 A+Q A ALG V ID ++K KS GA + ++ + ++ Sbjct: 189 AVQYAKALGL-RVLGIDGGADKGEFVKSLGAEVFVDFTKTKDVVAEVQKLTNGGPHGVIN 247 Query: 236 TAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWP 295 + P + +V+ ++ LVG + ++ + K + + GS++ Sbjct: 248 VSVSPHAINQSVQYVRTLGKVVLVGLPSG--AVVNSDVFWHVLKSIEIKGSYVGNR---- 301 Query: 296 GQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 ++ A L T + P+ A+ + A+ G+ ++ Sbjct: 302 -EDSAEAIDLFTRGLVK-API--KIIGLSELAKVYEQMEAGAIIGRYVV 346 >3UOG-A nrPDB Length = 363 Score = 207 bits (526), Expect = 7e-54, Method: Composition-based stats. Identities = 77/344 (22%), Positives = 129/344 (37%), Gaps = 28/344 (8%) Query: 9 DGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHY---YPITLGHEFSGYI 65 +++AE +PE + ++ V+ + L D + + G +P + SG + Sbjct: 38 PHDLKLAERPVPEA-GEHDIIVRTLAVSLNYRD-KLVLETGMGLDLAFPFVPASDMSGVV 95 Query: 66 DAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAK---YDFIGSRRDGGFAEYIV 122 +AVG V PGD V P L G + Y+ +G G +EY+V Sbjct: 96 EAVGKSVTRFRPGDRVISTFA------PGWLDGLRPGTGRTPAYETLGGAHPGVLSEYVV 149 Query: 123 VKRKNVFALPTDMPIEDGA--FIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCA 180 + A P + + + +T V++ G G + L +Q A Sbjct: 150 LPEGWFVAAPKSLDAAEASTLPCAGLTAWFALVEKGHLRAGDRVVVQGTGGVALFGLQIA 209 Query: 181 VALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVP 240 A GA V S EKL A + GA N E + L R ILE AG Sbjct: 210 KATGA-EVIVTSSSREKLDRAFALGADHGINRLEEDWVERVYALTGDRGADHILEIAGG- 267 Query: 241 QTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWE 300 + +++ P +++++G L S G +L K V G + + Sbjct: 268 AGLGQSLKAVAPDGRISVIGVLEGFE--VSGPVGPLLLKSPVVQGISVGHRR-------A 318 Query: 301 TASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 + +L L+P+I R F +A+ + R GKV++ Sbjct: 319 LEDLVGAVDRLGLKPVIDMRYKFTEVPEALAHLDRGPF-GKVVI 361 >3TWO-A nrPDB Length = 348 Score = 206 bits (525), Expect = 9e-54, Method: Composition-based stats. Identities = 73/334 (21%), Positives = 127/334 (38%), Gaps = 46/334 (13%) Query: 24 HQDEVRVKIASSGLCGSDLPRIFKNGA-HYYPITLGHEFSGYIDAVGSGVDDLHPGDAVA 82 +V + I +G+C SD+ + YP+ GHE +G I VG GV GD V Sbjct: 28 GPRDVLIDILYAGICHSDIHSAYSEWKEGIYPMIPGHEIAGIIKEVGKGVKKFKIGDVVG 87 Query: 83 CVPLL-PCFTCPECLKGFYSQCAKYDFI---------GSRRDGGFAEYIVVKRKNVFALP 132 + C C C + C K F GG++ IVV V ++ Sbjct: 88 VGCFVNSCKACKPCKEHQEQFCTKVVFTYDCLDSFHDNEPHMGGYSNNIVVDENYVISVD 147 Query: 133 TDMPIEDGAFIEPITVGLHAF---HLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVT 189 + P+E A + + G+ + ++ + V + G G +G +A++ AVA+GA V+ Sbjct: 148 KNAPLEKVAPL--LCAGITTYSPLKFSKVTKGTKVGVAGFGGLGSMAVKYAVAMGA-EVS 204 Query: 190 AIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEI 249 + K A S G + + ++ I+ T ++ +++ Sbjct: 205 VFARNEHKKQDALSMGVKHFYTDPKQCKEEL----------DFIISTIPTHYDLKDYLKL 254 Query: 250 AGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNY-------------SSPWP- 295 + LALVG ++ + F I V GS + + +P Sbjct: 255 LTYNGDLALVGLPPVEVAPVLSVFDFIHLGNRKVYGSLIGGIKETQEMVDFSIKHNIYPE 314 Query: 296 -----GQEWETASRLLTERKLSLEPLIAHRGSFE 324 G++ +TA LT K +I + SF+ Sbjct: 315 IDLILGKDIDTAYHNLTHGKAKFRYVIDMKKSFD 348 >1YQX-A nrPDB Length = 366 Score = 192 bits (489), Expect = 1e-49, Method: Composition-based stats. Identities = 73/265 (27%), Positives = 115/265 (43%), Gaps = 18/265 (6%) Query: 21 EIKHQDEVRVKIASSGLCGSDLPRIFKNGA-HYYPITLGHEFSGYIDAVGSGVDDLHPGD 79 +++VR K+ G+C SDL I + YP+ GHE G + VGS V ++ GD Sbjct: 37 RATGEEDVRFKVLYCGVCHSDLHSIKNDWGFSMYPLVPGHEIVGEVTEVGSKVKKVNVGD 96 Query: 80 AVACVPLL-PCFTCPECLKGFYSQCAKYDFI-------GSRRDGGFAEYIVVKRKNVFAL 131 V L+ C +C C + C K G+ GG++ ++V + + Sbjct: 97 KVGVGCLVGACHSCESCANDLENYCPKMILTYASIYHDGTITYGGYSNHMVANERYIIRF 156 Query: 132 PTDMPIEDGA--FIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVT 189 P +MP++ GA ITV + K++ I+G G +G +A++ A A G VT Sbjct: 157 PDNMPLDGGAPLLCAGITVYSPLKYFGLDEPGKHIGIVGLGGLGHVAVKFAKAFG-SKVT 215 Query: 190 AIDISSEKLALA-KSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVE 248 I S K A K+FGA S + QMQ+ L I++T + Sbjct: 216 VISTSPSKKEEALKNFGADSFLVSRDQ--EQMQAAAGTL---DGIIDTVSAVHPLLPLFG 270 Query: 249 IAGPHAQLALVGTLHQDLHLTSATF 273 + H +L LVG + L L + + Sbjct: 271 LLKSHGKLILVGAPEKPLELPAFSL 295 >3HZZ-A nrPDB Length = 467 Score = 189 bits (481), Expect = 1e-48, Method: Composition-based stats. Identities = 83/367 (22%), Positives = 134/367 (36%), Gaps = 43/367 (11%) Query: 12 VRVAESVIPEIKHQDEVRVKIASSGLCGSDL-PRIFK-----------------NGAHYY 53 + + E +PE+ E V + +S + + + IF+ H Sbjct: 76 IHLDEVPVPEL-GPGEALVAVMASSVNYNSVWTSIFEPVSTFAFLERYGKLSPLTKRHDL 134 Query: 54 PI-TLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSR 112 P +G + +G + G GV+ PGD V L P+ + + Sbjct: 135 PYHIIGSDLAGVVLRTGPGVNAWQPGDEVVAHCLSVELESPDGHDDTMLDPEQRIWGFET 194 Query: 113 RDGGFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHL------AQGCENKNVII 166 GG AE +VK + P + E+ A P V A+ A + NV+I Sbjct: 195 NFGGLAEIALVKTNQLMPKPKHLTWEEAA--APGLVNSTAYRQLVSRNGAAMKQGDNVLI 252 Query: 167 IGA-GTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEM-----SAPQM 220 GA G +G A Q A+A GA + + S +K + +S GA + + Sbjct: 253 WGASGGLGSYATQFALAGGANPICVVS-SPQKAEICRSMGAEAIIDRNAEGYKFWKDEHT 311 Query: 221 QSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKE 280 Q RF + I E G + +++ E G A V + +T+ E Sbjct: 312 QDPKEWKRFGKRIRELTGG-EDIDIVFEHPGRETFGASVYVTRKGGTITTCASTSGYMHE 370 Query: 281 LTVIGSWMN-----YSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIAR 335 WM+ S +E A+RL+ + K + P ++ S E QA D+ R Sbjct: 371 YDNRYLWMSLKRIIGSHFANYREAYEANRLIAKGK--IHPTLSKTYSLEETGQAAYDVHR 428 Query: 336 NAMPGKV 342 N GKV Sbjct: 429 NLHQGKV 435 >4J6F-A nrPDB Length = 382 Score = 189 bits (480), Expect = 2e-48, Method: Composition-based stats. Identities = 77/369 (20%), Positives = 133/369 (36%), Gaps = 44/369 (11%) Query: 1 MKSVVNDTDGIVR----VAESVIPEIKHQDEVRVKIASSGLCGSDL-------------- 42 M +V+ G + + +P EV +K+ + G+ +D+ Sbjct: 34 MTAVLLTGHGGLEKLVYSRDVPVP-APAAGEVLIKVTACGMNNTDVWVREGAYGTEDDPS 92 Query: 43 --PRIFKNGAHY-YPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGF 99 ++G +P G + G+I AVG GVD G+ V + Sbjct: 93 AVSTWRRHGNTLTFPRIQGTDTVGHIVAVGEGVDRARIGERVMVDFSI--------YNRD 144 Query: 100 YSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDM-PIEDGAFIEPITVGLHAFHLAQG 158 A D++G RDGG+AEY+ + +N + TD+ IE F G A+ Sbjct: 145 DDSLADIDYMGHGRDGGYAEYMALPAENAHVVATDLTDIELATFCCAYLTGERMLERARL 204 Query: 159 CENKNVIIIGA-GTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSA 217 + V++ GA G +G IQ A A GA + K A GA + Sbjct: 205 AAGETVLVTGASGGVGSAIIQLARARGAVPIAVAG--PGKEAAMLDIGAQAVVTRGQGDL 262 Query: 218 PQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKIL 277 + R ++ + G P ++I P + G + + + Sbjct: 263 AEAVEAASGGRPIDVVADLVGGPL-FNDLLKILRPEGRYTTAGAIAGP--VVQLDLRTMY 319 Query: 278 RKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNA 337 K+L + GS S ++ R + E+K + PL+ F +A D Sbjct: 320 LKQLELHGS-----SQGSRADFRRLVRYIEEKK--IRPLVGGVYPLSEFHRAQTDFMAKN 372 Query: 338 MPGKVLLIP 346 GK++++P Sbjct: 373 FVGKLVVVP 381 >1UUF-A nrPDB Length = 369 Score = 187 bits (474), Expect = 7e-48, Method: Composition-based stats. Identities = 77/336 (22%), Positives = 130/336 (38%), Gaps = 32/336 (9%) Query: 23 KHQDEVRVKIASSGLCGSDLPRIFKNG-AHYYPITLGHEFSGYIDAVGSGVDDLHPGDAV 81 ++V+++IA G+C SDL ++ YP GHE G + AVG V+ PGD V Sbjct: 45 PGPNDVKIEIAYCGVCHSDLHQVRSEWAGTVYPCVPGHEIVGRVVAVGDQVEKYAPGDLV 104 Query: 82 ACVPLL-PCFTCPECLKGFYSQCAKYDFIGSRRD--------GGFAEYIVVKRKNVFALP 132 ++ C C EC G + C + GG+++ IVV + V + Sbjct: 105 GVGCIVDSCKHCEECEDGLENYCDHMTGTYNSPTPDEPGHTLGGYSQQIVVHERYVLRIR 164 Query: 133 TDMPIEDGAFIEP-ITVGLHAF---HLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSV 188 P E A + P + G+ + Q K V ++G G +G + I+ A A+GA V Sbjct: 165 --HPQEQLAAVAPLLCAGITTYSPLRHWQAGPGKKVGVVGIGGLGHMGIKLAHAMGAH-V 221 Query: 189 TAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVE 248 A S K AK+ GA + NS + L+ IL T P ++ Sbjct: 222 VAFTTSEAKREAAKALGADEVVNSRNAD-----EMAAHLKSFDFILNTVAAPHNLDDFTT 276 Query: 249 IAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTE 308 + + LVG H + F ++ K + GS + + E Sbjct: 277 LLKRDGTMTLVGAP-ATPHKSPEVFN-LIMKRRAIAGSMIGG----IPETQEMLDFCAEH 330 Query: 309 RKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 ++ +I + +A + R + + ++ Sbjct: 331 GIVADIEMIRA----DQINEAYERMLRGDVKYRFVI 362 >5Z0C-A nrPDB Length = 374 Score = 185 bits (469), Expect = 3e-47, Method: Composition-based stats. Identities = 66/265 (24%), Positives = 108/265 (40%), Gaps = 18/265 (6%) Query: 21 EIKHQDEVRVKIASSGLCGSDLPRIFKNGA-HYYPITLGHEFSGYIDAVGSGVDDLHPGD 79 + +V K+ G+C SDL I + YP GHE G + VGS V+ GD Sbjct: 34 RATGELDVTFKVLYCGICHSDLHYIKNEWSNTIYPALPGHEIVGEVTEVGSKVNKFKVGD 93 Query: 80 AVACVPLL-PCFTCPECLKGFYSQCAKYD-------FIGSRRDGGFAEYIVVKRKNVFAL 131 V ++ C +CP C + C + G+ GG+++ +VV+ + Sbjct: 94 KVGVGCIVGSCHSCPNCNNHLENYCPNRILTFGSRYYDGTLNHGGYSDLMVVQEHFAVRI 153 Query: 132 PTDMPIEDGA--FIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVT 189 P +P++ A ITV + +V ++G G +G +A++ A A G K VT Sbjct: 154 PDALPLDSAAPLLCAGITVYSPLRYYGLDKPGLHVGVVGLGGLGHMAVKFAKAFGVK-VT 212 Query: 190 AIDISSEKLALAKS-FGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVE 248 + S K A S GA A QMQ+ + + I++T + + Sbjct: 213 VVSTSPAKKEDAISGLGAHSFI--LSTDAEQMQAAVGTM---DGIIDTVSASHPLPPLIS 267 Query: 249 IAGPHAQLALVGTLHQDLHLTSATF 273 + H +L +VG + L L Sbjct: 268 LLKSHGKLVMVGDPPKPLELPVFPL 292 >1YB5-A nrPDB Length = 351 Score = 182 bits (462), Expect = 2e-46, Method: Composition-based stats. Identities = 74/354 (20%), Positives = 135/354 (38%), Gaps = 42/354 (11%) Query: 1 MKSVV---NDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCG--SDLPRIFKNGAHYYPI 55 M++V ++++ + I +V +K+ + G+ + + + P Sbjct: 30 MRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPY 89 Query: 56 TLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDG 115 T G + +G I+AVG GD V F S G Sbjct: 90 TPGSDVAGVIEAVGDNASAFKKGDRV--------------------------FTSSTISG 123 Query: 116 GFAEYIVVKRKNVFALPTDMPIEDGAFIE-PITVGLHAF-HLAQGCENKNVIIIGA-GTI 172 G+AEY + V+ LP + + GA I P A H A ++V++ GA G + Sbjct: 124 GYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGV 183 Query: 173 GLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQL 232 GL A Q A A G K + + E + GA + FN E++ + + Sbjct: 184 GLAACQIARAYGLK-ILGTAGTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDI 242 Query: 233 ILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSS 292 I+E + + + ++ +VG+ + KE ++IG + S+ Sbjct: 243 IIEML-ANVNLSKDLSLLSHGGRVIVVGS----RGTIEINPRDTMAKESSIIGVTLFSST 297 Query: 293 PWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIAR-NAMPGKVLLI 345 Q++ A + E L+P+I + E A+A +I + GK++L+ Sbjct: 298 KEEFQQYAAALQAGMEIGW-LKPVIGSQYPLEKVAEAHENIIHGSGATGKMILL 350 >5VKT-A nrPDB Length = 362 Score = 177 bits (450), Expect = 5e-45, Method: Composition-based stats. Identities = 65/264 (24%), Positives = 108/264 (40%), Gaps = 20/264 (7%) Query: 21 EIKHQDEVRVKIASSGLCGSDLPRIFKNGAH-YYPITLGHEFSGYIDAVGSGVDDLHPGD 79 I+ +V +K+ G+C +DL I + YP+ GHE G + VG GV GD Sbjct: 30 RIQGDADVTIKVLFCGICHTDLHVIKNEWGNAMYPVVPGHEVVGVVTDVGHGVTKFKAGD 89 Query: 80 AVACVPLL-PCFTCPECLKGFYSQCAKYDFIGSRRD---------GGFAEYIVVKRKNVF 129 V + C TC C G + C + D GGF++ +VV + V Sbjct: 90 TVGVGYFVDSCRTCESCSTGHENYCPDLVLTSNGVDHHHHGATTKGGFSDVLVVSQDFVV 149 Query: 130 ALPTDMPIEDGA--FIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKS 187 +P +P++ A +TV A K++ ++G G +G +A++ A A G + Sbjct: 150 RVPESLPLDGAAPLLCAGVTVYSPMAQYALNEPGKHLGVVGLGGLGHMAVKFAKAFGM-T 208 Query: 188 VTAIDISSEKLALAK-SFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELA 246 VT I S K A GA S + + + + + I++T + Sbjct: 209 VTVISSSPGKRDEALGRLGADAFLVSHDAAQMKAAAATLDG-----IIDTVSAGHQIVPL 263 Query: 247 VEIAGPHAQLALVGTLHQDLHLTS 270 + + P Q+ +VG L L + Sbjct: 264 LALLKPMGQMVVVGAPSTPLELPA 287 >6C49-A nrPDB Length = 350 Score = 175 bits (445), Expect = 2e-44, Method: Composition-based stats. Identities = 71/327 (21%), Positives = 118/327 (36%), Gaps = 25/327 (7%) Query: 24 HQDEVRVKIASSGLCGSDLPRIFKNG-AHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVA 82 +V VK+ GLC SD+ + + YP+ GHE G I A+GS L G V Sbjct: 37 QPHQVEVKVEYCGLCHSDISVLNNEWHSTVYPVVAGHEIIGRIVALGSEAKGLQIGQRVG 96 Query: 83 CVPLL-PCFTCPECLKGFYSQCAKYDF-IGSRRDGGFAEYIVVKRKNVFALPTDMPIEDG 140 C C EC+ G C + GGFA+ + + LP D+ E Sbjct: 97 IGWTAESCQACDECIGGQQVLCTGENIATIVGHAGGFADKVRAGWQWAIPLPEDLDPESA 156 Query: 141 AFIEPITVGLHAFH---LAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEK 197 + + G+ F + +V +IG G +G +AI+ A G +TA + +K Sbjct: 157 GPL--LCGGITVFDPLLKHKIQATHHVGVIGIGGLGHIAIKLLKAWG-CEITAFSSNPDK 213 Query: 198 LALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLA 257 K+ GA NS + A + Q L+L T V + P+ L Sbjct: 214 TEELKAMGADHVVNSRDTEAVKAQK-----GKFDLLLSTVNVTLNWRAFISTLAPNGSLH 268 Query: 258 LVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLI 317 +G L + G ++ +V GS + +K++ + Sbjct: 269 FLGL---TLEPVPVSVGSLIDGAKSVTGS-----PTGSPAALRQLLKFAARKKIAPQ--- 317 Query: 318 AHRGSFESFAQAVRDIARNAMPGKVLL 344 +A+ + +++L Sbjct: 318 IELFPMSQLNEAIERLHSGQARYRIVL 344 >5FI5-A nrPDB Length = 357 Score = 175 bits (444), Expect = 2e-44, Method: Composition-based stats. Identities = 68/330 (20%), Positives = 122/330 (36%), Gaps = 25/330 (7%) Query: 21 EIKHQDEVRVKIASSGLCGSDLPRIF-KNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGD 79 + +V++K+ G C D K G YP LGHE G + VGS V GD Sbjct: 38 RATGEHDVQLKVLYCGTCQYDREMSKNKFGFTSYPYVLGHEIVGEVTEVGSKVQKFKVGD 97 Query: 80 AVACVPLL-PCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIE 138 V ++ C C C + C + I S G + V+ V P ++P++ Sbjct: 98 KVGVASIIETCGKCEMCTNEVENYCPEAGSIDSNY-GACSNIAVINENFVIRWPENLPLD 156 Query: 139 DGAFIEPITVGLHAF----HLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDIS 194 G + + G+ A+ K + I G G +G +A++ A A GAK Sbjct: 157 SGVPL--LCAGITAYSPMKRYGLDKPGKRIGIAGLGGLGHVALRFAKAFGAKVTVISSSL 214 Query: 195 SEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHA 254 +K + FGA SS +MQ L I++T ++E + + P Sbjct: 215 KKKREAFEKFGADSFLVSSN--PEEMQGAAGTL---DGIIDTIPGNHSLEPLLALLKPLG 269 Query: 255 QLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLE 314 +L ++G + + + G M S+ +E + E + + Sbjct: 270 KLIILGAPEMPFEVPAPSLLMG--------GKVMAASTAGSMKEIQEMIEFAAEHNIVAD 321 Query: 315 PLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 + S + A+ + + + + ++ Sbjct: 322 VEV---ISIDYVNTAMERLDNSDVRYRFVI 348 >1Q1N-A nrPDB Length = 360 Score = 170 bits (431), Expect = 7e-43, Method: Composition-based stats. Identities = 63/341 (18%), Positives = 121/341 (35%), Gaps = 31/341 (9%) Query: 20 PEIKHQDEVRVKIASSGLCGSDLPRIFKNGAH-YYPITLGHEFSGYIDAVGSGVD-DLHP 77 P+ + ++ +KI + G+CGSD+ + + P+ +GHE G + +G + L Sbjct: 28 PKPFYDHDIDIKIEACGVCGSDIHCAAGHWGNMKMPLVVGHEIVGKVVKLGPKSNSGLKV 87 Query: 78 GDAVACVP-LLPCFTCPECLKGFYSQCAKYDFI-------GSRRDGGFAEYIVVKRKNVF 129 G V + C C C C K+ G GG+A Y+ V V Sbjct: 88 GQRVGVGAQVFSCLECDRCKNDNEPYCTKFVTTYSQPYEDGYVSQGGYANYVRVHEHFVV 147 Query: 130 ALPTDMPIEDGA-FIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSV 188 +P ++P A + K V I+G G IG + + A+GA++ Sbjct: 148 PIPENIPSHLAAPLLCGGLTVYSPLVRNGCGPGKKVGIVGLGGIGSMGTLISKAMGAET- 206 Query: 189 TAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAV- 247 I SS K A GA + E + LI+ A ++ + Sbjct: 207 YVISRSSRKREDAMKMGADHYIATLEEGDWGEKYFDT----FDLIVVCASSLTDIDFNIM 262 Query: 248 -EIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLL 306 + ++ + Q L+ +G + ++YS+ +E +L+ Sbjct: 263 PKAMKVGGRIVSISIPEQHEMLSLKPYG--------LKAVSISYSALGSIKELNQLLKLV 314 Query: 307 TERKLSLEPLIAHRGSFES--FAQAVRDIARNAMPGKVLLI 345 +E+ + + +A + + + + L+ Sbjct: 315 SEKDIKI---WVETLPVGEAGVHEAFERMEKGDVRYRFTLV 352 >5H82-A nrPDB Length = 389 Score = 168 bits (426), Expect = 3e-42, Method: Composition-based stats. Identities = 57/296 (19%), Positives = 97/296 (32%), Gaps = 32/296 (10%) Query: 19 IPEIKHQDEVRVKIASSGLCGSDLPRIFKN-GAHYYPITLGHEFSGYIDAVGSGVDDLHP 77 + + +V+ K+ GLC D+ G YP GHE G + +G+ V Sbjct: 47 LRRTTGEHDVQFKVLYCGLCDWDVITTKNTYGTTKYPFVPGHEIMGIVTEIGNKVKKFKV 106 Query: 78 GDAVAC-VPLLPCFTCPECLKGFYSQCAKYDFIGSRRD--------------------GG 116 GD V + C C C +G C K + GG Sbjct: 107 GDKVGVGNFIGSCGKCERCNEGLEPYCPKVIYTDGTAFSDENNTVYGDVSGDGEDRIYGG 166 Query: 117 FAEYIVVKRKNVFALPTDMPIEDGA--FIEPITVGLHAFHLAQGCENKNVIIIGAGTIGL 174 ++ +V VF P ++P+ G I H ++ ++G G IG Sbjct: 167 YSNIMVANEYVVFRWPENLPLAAGVPILCGGIVPYSPMRHFGLDKPGLSIGVVGFGRIGK 226 Query: 175 LAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLIL 234 LA++ A A GA S+K + +G + S E +M++ L I Sbjct: 227 LAVKFAKAFGANVTVISTSISKKQEAIEKYGVDRFLISKE--PEEMKAAESTL---DGIF 281 Query: 235 ETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNY 290 + + + + ++G + L +L +GS Sbjct: 282 DCVPSVHPLHPLLNLLKFEGTFVMLGVAVEAYEL---PVSPLLMGRRKFVGSISGT 334 >2DPH-A nrPDB Length = 398 Score = 168 bits (426), Expect = 3e-42, Method: Composition-based stats. Identities = 72/391 (18%), Positives = 120/391 (30%), Gaps = 49/391 (12%) Query: 2 KSVVNDTDGIVRVAESVIPEIKH-----QDEVRVKIASSGLCGSDLPRIFKNGAHYYPIT 56 KSVV +RV P+++H + V +K+ S+ +CGSD Sbjct: 4 KSVVYHGTRDLRVETVPYPKLEHNNRKLEHAVILKVVSTNICGSDQHIYRGRFIVPKGHV 63 Query: 57 LGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAK----------- 105 LGHE +G + GS V+ + GD V+ + C C C + C Sbjct: 64 LGHEITGEVVEKGSDVELMDIGDLVSVPFNVACGRCRNCKEARSDVCENNLVNPDADLGA 123 Query: 106 YDFIGSRRDGGFAEYIVVKRKNVFALPTD------MPIEDGAFIEP-ITVGLHAFHLAQG 158 + F GG AEY++V + L I+D I + G H A Sbjct: 124 FGFDLKGWSGGQAEYVLVPYADYMLLKFGDKEQAMEKIKDLTLISDILPTGFHGCVSAGV 183 Query: 159 CENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAP 218 +V I GAG +G A A LGA V D + E+L L G + Sbjct: 184 KPGSHVYIAGAGPVGRCAAAGARLLGAACVIVGDQNPERLKLLSDAGFETIDLRNSAPLR 243 Query: 219 QMQSVLRELRFNQLILETAGVPQ--------------TVELAVEIAGPHAQLAL----VG 260 + ++ G + ++ + + VG Sbjct: 244 DQIDQILGKPEVDCGVDAVGFEAHGLGDEANTETPNGALNSLFDVVRAGGAIGIPGIYVG 303 Query: 261 TLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHR 320 + ++ + + L S + P + L P ++ Sbjct: 304 SDPDPVNKDAGSGRLHLDFGKMWTKSIRIMTGMAPVTNYNR--HLTEAILWDQMPYLSKV 361 Query: 321 G-----SFESFAQAVRDIARNAMPGKVLLIP 346 + + P K ++ P Sbjct: 362 MNIEVITLDQAPDGYAKF-DKGSPAKFVIDP 391 >2VCY-A nrPDB Length = 344 Score = 166 bits (421), Expect = 1e-41, Method: Composition-based stats. Identities = 75/360 (20%), Positives = 139/360 (38%), Gaps = 47/360 (13%) Query: 1 MKSVVN-DTDGIVRVAESVIPEIK--HQDEVRVKIASSGLCGSDLPRIFKNGA--HYYPI 55 ++++V +V E E+ +VRVK+ ++ + SD+ I N P Sbjct: 14 VRALVYGHHGDPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGLLPELPA 73 Query: 56 TLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDG 115 G+E + AVGS V L PGD V A R + Sbjct: 74 VGGNEGVAQVVAVGSNVTGLKPGDWVIP--------------------ANAGLGTWRTEA 113 Query: 116 GFAEYIVVKRKNVFALPTDMPIEDGAFIE--PITVGLHAFHLAQGCENKNVIIIGAG-TI 172 F+E +++ +P+D+P++ A + P T Q +VI + + Sbjct: 114 VFSEEALIQ------VPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGV 167 Query: 173 GLLAIQCAVALGAKSVTAIDISSE--KL-ALAKSFGAMQTFNSSEMSAPQMQSVLRELRF 229 G IQ A ALG +++ + + KL KS GA E+ P+M++ +++ Sbjct: 168 GQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEEELRRPEMKNFFKDMPQ 227 Query: 230 NQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMN 289 +L L G + EL ++A + G Q A+ ++ K+L + G W++ Sbjct: 228 PRLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQP---VVASVSLLIFKDLKLRGFWLS 284 Query: 290 -----YSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 +S + T L+ +L P + + + + A+ + + K +L Sbjct: 285 QWKKDHSPDQFKELILTLCDLIRRGQL-TAPACS-QVPLQDYQSALEASMKPFISSKQIL 342 >4OAQ-A nrPDB Length = 367 Score = 166 bits (421), Expect = 1e-41, Method: Composition-based stats. Identities = 75/312 (24%), Positives = 117/312 (37%), Gaps = 34/312 (10%) Query: 25 QDEVRVKIASSGLCGSDLPRIFKNGAHYY--PITLGHEFSGYIDAVGSGVDDLHPGDAVA 82 +V +K GLC SD+ + + +GHE G + AVG V + GD V Sbjct: 35 PHDVVLKNEVCGLCYSDIHTLSAGWQPLQRDNLVVGHEIIGEVIAVGDEVTEFKVGDRVG 94 Query: 83 CVPL-LPCFTCPECLKGFYSQCAKYDFIGSRRD---------GGFAEYIVVKRKNVFALP 132 C +C C C + + +D GG++ + + K VFA+P Sbjct: 95 IGAASSSCRSCQRCDSDNEQYCKQGAATYNSKDVRSNNYVTQGGYSSHSIADEKFVFAIP 154 Query: 133 TDMPIEDGAFIEPITVGLHAF-----HLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKS 187 D+P GA + + G+ F +L KNV IIG G +G LA+Q A A+GA + Sbjct: 155 EDLPSSYGAPL--MCAGITVFSPLIRNLGLDARGKNVGIIGIGGLGHLALQFANAMGA-N 211 Query: 188 VTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELA- 246 VTA SS K A GA ++ ++ IL A + L+ Sbjct: 212 VTAFSRSSSKKEQAMKLGAHDFV-ATGEDKTWYKNY---DDHFDFILNCASGIDGLNLSE 267 Query: 247 -VEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRL 305 + + VG + + F + G+ S E + L Sbjct: 268 YLSTLKVDKKFVSVGLPPSEDKFEVSPFTFLQ------QGASFGSSLLGSKTEVKEMLNL 321 Query: 306 LTERKLSLEPLI 317 K ++ P+I Sbjct: 322 AA--KHNVRPMI 331 >3QWB-A nrPDB Length = 334 Score = 164 bits (415), Expect = 5e-41, Method: Composition-based stats. Identities = 66/356 (18%), Positives = 129/356 (36%), Gaps = 48/356 (13%) Query: 2 KSVVNDTDG---IVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLG 58 K ++ D G +++ + +P I ++E+ +K +G+ + P LG Sbjct: 10 KVILIDEIGGYDVIKYEDYPVPSI-SEEELLIKNKYTGVNYIESYFRKGIYPCEKPYVLG 68 Query: 59 HEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFA 118 E SG + A G GV + GD VA + + FA Sbjct: 69 REASGTVVAKGKGVTNFEVGDQVAYI----------------------------SNSTFA 100 Query: 119 EYIVVKRKN-VFALPTDMPIED-----GAFIEPITVGLHAFHLAQGCENKNVIIIGA-GT 171 +Y + + V LP E+ ++ +T + V++ A G Sbjct: 101 QYSKISSQGPVMKLPKGTSDEELKLYAAGLLQVLTALSFTNEAYHVKKGDYVLLFAAAGG 160 Query: 172 IGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQ 231 +GL+ Q GA ++ A+ + EKL +AK +GA N+S+ + + Sbjct: 161 VGLILNQLLKMKGAHTI-AVASTDEKLKIAKEYGAEYLINASKEDILRQVLKFTNGKGVD 219 Query: 232 LILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELT-VIGSWMNY 290 ++ G T E+++ V + + + ++ K +T V Y Sbjct: 220 ASFDSVG-KDTFEISLAALKRKG--VFVSFGNASGLIPPFSITRLSPKNITLVRPQLYGY 276 Query: 291 SSPWPGQEW--ETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 + ++ + L+ +KL+++ I + A DI GK++L Sbjct: 277 IADPEEWKYYSDEFFGLVNSKKLNIK--IYKTYPLRDYRTAAADIESRKTVGKLVL 330 >5H83-A nrPDB Length = 360 Score = 162 bits (410), Expect = 2e-40, Method: Composition-based stats. Identities = 61/260 (23%), Positives = 97/260 (37%), Gaps = 12/260 (4%) Query: 21 EIKHQDEVRVKIASSGLCGSDLPR-IFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGD 79 +++V+ K+ G C DL K G YP +GHE G + +GS V GD Sbjct: 35 RATGENDVQFKVLYCGTCNYDLEMSTNKFGMTKYPFVIGHEIVGVVTEIGSKVQKFKVGD 94 Query: 80 AVACVPLL-PCFTCPECLKGFYSQCAKYDFIG---SRRDGGFAEYIVVKRKNVFALPTDM 135 V + C C C+ G + C+K + GG +VV K P ++ Sbjct: 95 KVGVGGFVGACEKCEMCVNGVENNCSKVESTDGHFGNNFGGCCNIMVVNEKYAVVWPENL 154 Query: 136 PIEDGA--FIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDI 193 P+ G IT N+ I G G +G LAI+ A A GAK Sbjct: 155 PLHSGVPLLCAGITTYSPLRRYGLDKPGLNIGIAGLGGLGHLAIRFAKAFGAKVTLISSS 214 Query: 194 SSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPH 253 +K + FG + +MQ L I++T V ++ + + P Sbjct: 215 VKKKREALEKFGVDSFL--LNSNPEEMQGAYGTL---DGIIDTMPVAHSIVPFLALLKPL 269 Query: 254 AQLALVGTLHQDLHLTSATF 273 +L ++G + + + Sbjct: 270 GKLIILGVPEEPFEVPAPAL 289 >4JLW-A nrPDB Length = 399 Score = 162 bits (409), Expect = 2e-40, Method: Composition-based stats. Identities = 62/263 (23%), Positives = 98/263 (37%), Gaps = 23/263 (8%) Query: 2 KSVVNDTDGIVRVAESVIPEIKHQ------DEVRVKIASSGLCGSDLPRIFKNGAHYYPI 55 + VV G V V P+++ V +++ S+ +CGSD + + Sbjct: 5 RGVVYLGPGKVEVQNIPYPKMQDPQGRQIDHGVILRVVSTNICGSDQHMVRGRTTAPEGL 64 Query: 56 TLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQC---------AKY 106 LGHE +G + +G GV+ + GD V+ + C C C + C Y Sbjct: 65 VLGHEITGEVVEIGRGVETMKIGDLVSVPFNVACGHCRTCKEQHTGVCLTVNPARAGGAY 124 Query: 107 DFIG-SRRDGGFAEYIVVKRK--NVFALPTDMPIED-----GAFIEPITVGLHAFHLAQG 158 ++ GG AEY++V N+ LP + + + G H A Sbjct: 125 GYVDMGGWVGGQAEYVLVPYADFNLLKLPNREAAMEKIRDLTCLSDILPTGYHGAVTAGV 184 Query: 159 CENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAP 218 V I GAG +GL A A LGA V D++ +LA AK G S + Sbjct: 185 GPGSTVYIAGAGPVGLAAAASARLLGAAVVIVGDVNPTRLAHAKKQGFEIADLSKDTPLH 244 Query: 219 QMQSVLRELRFNQLILETAGVPQ 241 + + L ++ G Sbjct: 245 EQIAALLGEPEVDCAVDAVGFEA 267 >1KOL-A nrPDB Length = 398 Score = 158 bits (400), Expect = 3e-39, Method: Composition-based stats. Identities = 73/389 (18%), Positives = 133/389 (34%), Gaps = 45/389 (11%) Query: 2 KSVVNDTDGIVRVAESVIPEIKHQ------DEVRVKIASSGLCGSDLPRIFKNGAHYYPI 55 + VV G V V + P+++ V +K+ S+ +CGSD + + Sbjct: 4 RGVVYLGSGKVEVQKIDYPKMQDPRGKKIEHGVILKVVSTNICGSDQHMVRGRTTAQVGL 63 Query: 56 TLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQC---------AKY 106 LGHE +G + G V++L GD V+ + C C C + C Y Sbjct: 64 VLGHEITGEVIEKGRDVENLQIGDLVSVPFNVACGRCRSCKEMHTGVCLTVNPARAGGAY 123 Query: 107 DFIG-SRRDGGFAEYIVVKRK--NVFALPTDMPIED-----GAFIEPITVGLHAFHLAQG 158 ++ GG AEY++V N+ LP + + + G H A Sbjct: 124 GYVDMGDWTGGQAEYVLVPYADFNLLKLPDRDKAMEKIRDLTCLSDILPTGYHGAVTAGV 183 Query: 159 CENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAP 218 V + GAG +GL A A LGA V D++ +LA AK+ G S + Sbjct: 184 GPGSTVYVAGAGPVGLAAAASARLLGAAVVIVGDLNPARLAHAKAQGFEIADLSLDTPLH 243 Query: 219 QMQSVLRELRFNQLILETAGVPQ---------------TVELAVEIAGPHAQLALVGTLH 263 + + L ++ G + +++ ++ + G Sbjct: 244 EQIAALLGEPEVDCAVDAVGFEARGHGHEGAKHEAPATVLNSLMQVTRVAGKIGIPGLYV 303 Query: 264 QDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQE-----WETASRLLTERKLSLEPLIA 318 + KI + W S GQ + + ++++ ++ Sbjct: 304 TEDPGAVDAAAKIGSLSIRFGLGWAKSHSFHTGQTPVMKYNRALMQAIMWDRINIAEVVG 363 Query: 319 -HRGSFESFAQAVRDIARNAMPGKVLLIP 346 S + + + +P K ++ P Sbjct: 364 VQVISLDDAPRGYGEF-DAGVPKKFVIDP 391 >3TQH-A nrPDB Length = 321 Score = 158 bits (400), Expect = 3e-39, Method: Composition-based stats. Identities = 67/355 (18%), Positives = 130/355 (36%), Gaps = 54/355 (15%) Query: 1 MKSVVNDTDGI---VRVAESVIPEIKHQDEVRVKIASSGLCGSDLPR------IFKNGAH 51 MK++ D G +++ ++ PE + +++ +K+ ++ L D + K + Sbjct: 7 MKAIQFDQFGPPKVLKLVDTPTPEYRK-NQMLIKVHAASLNPIDYKTRNGSGFVAKKLKN 65 Query: 52 YYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGS 111 P LG++FSG + +GS V++++ GD V + P C C Sbjct: 66 NLPSGLGYDFSGEVIELGSDVNNVNIGDKVMGIAGFPDHPC--C---------------- 107 Query: 112 RRDGGFAEYIVVKRKNVFALPTDMP-IEDGAFIEPITVGLHAFHLAQGCENKNVII-IGA 169 +AEY+ + + ++ + L A + A+ + V+I GA Sbjct: 108 -----YAEYVCASPDTIIQKLEKLSFLQAASLPTAGLTALQALNQAEVKQGDVVLIHAGA 162 Query: 170 GTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRF 229 G +G LAIQ A G +T S A K+ GA Q N E S Sbjct: 163 GGVGHLAIQLAKQKGTTVIT--TASKRNHAFLKALGAEQCINYHEEDFLLAIS-----TP 215 Query: 230 NQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMN 289 +++ G + +++ + V + T G+++ Sbjct: 216 VDAVIDLVGGDVGI-QSIDCLKETGCIVSV---------PTITAGRVIEVAKQKHRRAFG 265 Query: 290 YSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 + +E +L++E KL +E I+ A + + GK++ Sbjct: 266 LLKQFNIEELHYLGKLVSEDKLRIE--ISRIFQLSEAVTAHELLETGHVRGKLVF 318 >3JYN-A nrPDB Length = 325 Score = 153 bits (387), Expect = 1e-37, Method: Composition-based stats. Identities = 74/353 (20%), Positives = 127/353 (35%), Gaps = 38/353 (10%) Query: 2 KSVVNDTDGIVRVAESV--IPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYY-PITLG 58 K + T G V E V PE V V+ + GL D + P LG Sbjct: 3 KRIQFSTVGGPEVLEYVDFEPEAPGPQAVVVRNKAIGLNFIDTYYRSGLYPAPFLPSGLG 62 Query: 59 HEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFA 118 E +G ++AVG V GD VA G+ G ++ Sbjct: 63 AEGAGVVEAVGDEVTRFKVGDRVAY--------------------------GTGPLGAYS 96 Query: 119 EYIVVKRKNVFALPTDMPIEDGA--FIEPITVGLHAFHLAQGCENKNVII-IGAGTIGLL 175 E V+ N+ L + E A ++ +TV Q + ++ AG +G L Sbjct: 97 EVHVLPEANLVKLADSVSFEQAAALMLKGLTVQYLLRQTYQVKPGEIILFHAAAGGVGSL 156 Query: 176 AIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILE 235 A Q A ALGAK + S EK A AK+ GA +T + S + L + + ++ + Sbjct: 157 ACQWAKALGAK-LIGTVSSPEKAAHAKALGAWETIDYSHEDVAKRVLELTDGKKCPVVYD 215 Query: 236 TAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSS--P 293 G T +++ P + G + + + +Y++ Sbjct: 216 GVG-QDTWLTSLDSVAPRGLVVSFGNASGPVSGVNLGILAQKDSVYVTRPTLGSYANNAQ 274 Query: 294 WPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP 346 + +L KL ++ + + + + A+A +++ G +LIP Sbjct: 275 NLQTMADELFDMLASGKLKVDGI--EQYALKDAAKAQIELSARRTTGSTILIP 325 >4RVS-A nrPDB Length = 329 Score = 150 bits (379), Expect = 9e-37, Method: Composition-based stats. Identities = 64/348 (18%), Positives = 114/348 (32%), Gaps = 39/348 (11%) Query: 8 TDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFSGYIDA 67 G++R + P+ H E+ +K + G+ D P +G E G ++A Sbjct: 12 GPGVLRHVDQPQPQPGH-GELLIKAEAIGVNFIDTYFRSGQYPRELPFVIGSEVCGTVEA 70 Query: 68 VGSGV----DDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVV 123 VG GV + GD V + +G +AE+ Sbjct: 71 VGPGVTAADTAISVGDRVV---------------------------SASANGAYAEFCTA 103 Query: 124 KRKNVFALPTDMPIEDG--AFIEPITVGLHAFHLAQGCENKNVII-IGAGTIGLLAIQCA 180 +P D+ E A ++ +T + V++ GAG +GL+ Q A Sbjct: 104 PASLTAKVPDDVTSEVAASALLKGLTAHYLLKSVYPVKRGDTVLVHAGAGGVGLILTQWA 163 Query: 181 VALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSA--PQMQSVLRELRFNQLILETAG 238 LG + +T + +EK L+K GA + E + L Q + + G Sbjct: 164 THLGVRVITTVST-AEKAKLSKDAGADVVLDYPEDAWQFAGRVRELTGGTGVQAVYDGVG 222 Query: 239 VPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQE 298 T + ++ LAL G + S +++ Sbjct: 223 A-TTFDASLASLAVRGTLALFGAASGPVPPVDPQRLNAAGSVYLTRPSLFHFTRTGEEFS 281 Query: 299 WETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP 346 W A ++ + R +A +D+ G V+L+P Sbjct: 282 WRAAELFDAIGNEAITVAVGGRYPLADALRAHQDLEARKTVGSVVLLP 329 >2OBY-A nrPDB Length = 338 Score = 143 bits (361), Expect = 1e-34, Method: Composition-based stats. Identities = 76/359 (21%), Positives = 119/359 (33%), Gaps = 46/359 (12%) Query: 1 MKSVVNDTDG---IVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPI-- 55 M +V D G + V E P + EV +K+A+S L +DL + Sbjct: 7 MLAVHFDKPGGPENLYVKEVAKPS-PGEGEVLLKVAASALNRADLMQRQGQYDPPPGASN 65 Query: 56 TLGHEFSGYIDAVGSGVDD-LHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRD 114 LG E SG++ +G G GD + Sbjct: 66 ILGLEASGHVAELGPGCQGHWKIGDTAMAL---------------------------LPG 98 Query: 115 GGFAEYIVVKRKNVFALPTDMPI-EDGAFIEPITVGLHAFHL-AQGCENKNVII-IGAGT 171 GG A+Y+ V + +P + + + A E HL V+I G Sbjct: 99 GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSG 158 Query: 172 IGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQ 231 +G AIQ GA + S +KL +A+ GA FN + + + Sbjct: 159 VGTAAIQLTRMAGAIPL-VTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVN 217 Query: 232 LILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYS 291 LIL+ G E V + L G + + F K+L K ++I S + Sbjct: 218 LILDCIGGSY-WEKNVNCLALDGRWVLYGLMGGGD-INGPLFSKLLFKRGSLITSLLRSR 275 Query: 292 SPWPGQEWETA------SRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 Q A TE L P++ +A + + N GK++L Sbjct: 276 DNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVL 334 >4A10-A nrPDB Length = 447 Score = 142 bits (359), Expect = 2e-34, Method: Composition-based stats. Identities = 78/380 (20%), Positives = 134/380 (35%), Gaps = 63/380 (16%) Query: 12 VRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPI---------------- 55 +R+ E +PE+ DEV V + +S + ++ P Sbjct: 50 LRLGEVPMPELA-PDEVLVAVMASSIN---YNTVWSAMFEPIPTFHFLKQNARQGGWATR 105 Query: 56 ------TLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFI 109 LG + SG + G GV PGD V P P + + Sbjct: 106 HDQPYHVLGSDCSGVVVRTGIGVRRWKPGDHVIVHPAHVDEQEPATHGDGMLGTEQRAWG 165 Query: 110 GSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHL------AQGCENKN 163 GG AEY VV+ + P + E+ A + P+ G A+ + AQ + Sbjct: 166 FETNFGGLAEYGVVRASQLLPKPAHLTWEEAA-VSPLCAG-TAYRMLVSDRGAQMKQGDI 223 Query: 164 VIIIGA-GTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQS 222 V+I GA G +G AIQ G V + S++K A ++ G N +E+ + Sbjct: 224 VLIWGASGGLGSYAIQFVKNGGGIPVAVVS-SAQKEAAVRALGCDLVINRAELGITDDIA 282 Query: 223 -----------------VLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQD 265 V + R ++ E G T L+V +A + G+ Sbjct: 283 DDPRRVVETGRKLAKLVVEKAGREPDIVFEHTGRV-TFGLSVIVARRGGTVVTCGSSSG- 340 Query: 266 LHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFES 325 +L + + K ++GS +E + +RL ++ P ++ Sbjct: 341 -YLHTFDNRYLWMKLKKIVGSHGANH-----EEQQATNRLFESG--AVVPAMSAVYPLAE 392 Query: 326 FAQAVRDIARNAMPGKVLLI 345 A+A R + + GKV ++ Sbjct: 393 AAEACRVVQTSRQVGKVAVL 412 >1WLY-A nrPDB Length = 333 Score = 134 bits (338), Expect = 5e-32, Method: Composition-based stats. Identities = 62/357 (17%), Positives = 122/357 (34%), Gaps = 39/357 (10%) Query: 1 MKSVVNDTDGIVRVA-ESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNG----AHYYPI 55 M +V++ G E V +VR++ + G+ D PI Sbjct: 3 MAAVIHKKGGPDNFVWEEVKVGSPGPGQVRLRNTAIGVNFLDTYHRAGIPHPLVVGEPPI 62 Query: 56 TLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDG 115 +G E + ++ VG GV D G+ V CL G Sbjct: 63 VVGFEAAAVVEEVGPGVTDFTVGERVCT-----------CLPPL---------------G 96 Query: 116 GFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLA----QGCENKNVII-IGAG 170 +++ + + + +P D+ ++D + G+ A +L + V+I AG Sbjct: 97 AYSQERLYPAEKLIKVPKDLDLDDVHLAGLMLKGMTAQYLLHQTHKVKPGDYVLIHAAAG 156 Query: 171 TIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFN 230 +G + + A LGA +V + EK A+ G T N S ++ + + Sbjct: 157 GMGHIMVPWARHLGA-TVIGTVSTEEKAETARKLGCHHTINYSTQDFAEVVREITGGKGV 215 Query: 231 QLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTV-IGSWMN 289 ++ ++ G T++ +++ P A G +R L + + + Sbjct: 216 DVVYDSIG-KDTLQKSLDCLRPRGMCAAYGHASGVADPIRVVEDLGVRGSLFITRPALWH 274 Query: 290 YSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP 346 Y S + + + L +A A A + + G ++L+P Sbjct: 275 YMSNRSEIDEGSKCLFDAVKAGVLHSSVAKTFPLREAAAAHKYMGGRQTIGSIVLLP 331 >1QOR-A nrPDB Length = 327 Score = 130 bits (327), Expect = 8e-31, Method: Composition-based stats. Identities = 60/347 (17%), Positives = 115/347 (33%), Gaps = 35/347 (10%) Query: 6 NDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHY-YPITLGHEFSGY 64 + +++ E P ++E++V+ + G+ D P LG E +G Sbjct: 10 HGGPEVLQAVEF-TPADPAENEIQVENKAIGINFIDTYIRSGLYPPPSLPSGLGTEAAGI 68 Query: 65 IDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVK 124 + VGSGV + GD V G ++ + Sbjct: 69 VSKVGSGVKHIKAGDRVVYA--------------------------QSALGAYSSVHNII 102 Query: 125 RKNVFALPTDMPIEDGA--FIEPITVGLHAFHLAQGCENKNVII-IGAGTIGLLAIQCAV 181 LP + E A F++ +TV + ++ + AG +GL+A Q A Sbjct: 103 ADKAAILPAAISFEQAAASFLKGLTVYYLLRKTYEIKPDEQFLFHAAAGGVGLIACQWAK 162 Query: 182 ALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQ 241 ALGAK + + ++K A GA Q N E + + + +++ ++ G Sbjct: 163 ALGAKLIGTVGT-AQKAQSALKAGAWQVINYREEDLVERLKEITGGKKVRVVYDSVGRD- 220 Query: 242 TVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNY--SSPWPGQEW 299 T E +++ + G + + S Y + + Sbjct: 221 TWERSLDCLQRRGLMVSFGNSSGAVTGVNLGILNQKGSLYVTRPSLQGYITTREELTEAS 280 Query: 300 ETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP 346 L+ + ++ + + +A + A G LLIP Sbjct: 281 NELFSLIASGVIKVDVAEQQKYPLKDAQRAHEILESRATQGSSLLIP 327 >2VN8-A nrPDB Length = 375 Score = 130 bits (326), Expect = 1e-30, Method: Composition-based stats. Identities = 75/378 (19%), Positives = 124/378 (32%), Gaps = 72/378 (19%) Query: 6 NDTDGIVRV-AESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAH------------- 51 + ++R ++P I + +EV VK+ ++ + D+ GA Sbjct: 30 YGKNEVLRFTQNMMMPIIHYPNEVIVKVHAASVNPIDVNMRSGYGATALNMKRDPLHVKI 89 Query: 52 ---YYPITLGHEFSGYIDAVGSGVDDLHPGDAV--ACVPLLPCFTCPECLKGFYSQCAKY 106 +P+TLG + SG + G V PGD V A P Sbjct: 90 KGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPW-------------------- 129 Query: 107 DFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAFIEPIT-VGLHAFHLAQG-----CE 160 + G +E++VV V P + A + + A + G C Sbjct: 130 ------KQGTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCT 183 Query: 161 NKNVIIIGA-GTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQ 219 K V+I+GA G +G AIQ A A VTA+ S + L + GA + S + Sbjct: 184 GKRVLILGASGGVGTFAIQVMKAWDAH-VTAV-CSQDASELVRKLGADDVIDYKSGSVEE 241 Query: 220 MQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLH-------LTSAT 272 L+ L+ IL+ G T A + + V + L Sbjct: 242 Q---LKSLKPFDFILDNVGG-STETWAPDFLKKWSGATYVTLVTPFLLNMDRLGIADGML 297 Query: 273 FGKILRKELTVIGSWMNYSSPW-----PGQEWETASRLLTERKLSLEPLIAHRGSFESFA 327 + + W W G + + L+ K + P+I F Sbjct: 298 QTGVTVGSKALKHFWKGVHYRWAFFMASGPCLDDIAELVDAGK--IRPVIEQTFPFSKVP 355 Query: 328 QAVRDIARNAMPGKVLLI 345 +A + R GK ++ Sbjct: 356 EAFLKVERGHARGKTVIN 373 >4EYE-A nrPDB Length = 342 Score = 125 bits (315), Expect = 2e-29, Method: Composition-based stats. Identities = 66/358 (18%), Positives = 126/358 (35%), Gaps = 49/358 (13%) Query: 1 MKSVV---NDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHY--YPI 55 MK++ + + P + V V + ++G+C D P Sbjct: 22 MKAIQAQSLSGPEGLVYTDVETPGA-GPNVVVVDVKAAGVCFPDYLMTKGEYQLKMEPPF 80 Query: 56 TLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDG 115 G E +G + + G + PGD V + G Sbjct: 81 VPGIETAGVVRSAPEG-SGIKPGDRVMAFNFI---------------------------G 112 Query: 116 GFAEYIVVKRKNVFALPTDMPI-EDGAFIEPITVGLHAF-HLAQGCENKNVIIIGAGTIG 173 G+AE + V N+ P + E A I A+ Q + V+++GA Sbjct: 113 GYAERVAVAPSNILPTPPQLDDAEAVALIANYHTMYFAYARRGQLRAGETVLVLGAAGGI 172 Query: 174 LL-AIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQL 232 AIQ A +GAK + ++ ++ KS GA E + + Sbjct: 173 GTAAIQIAKGMGAKVIAVVNRTAA-TEFVKSVGADIVL-PLEEGWAKAVREATGGAGVDM 230 Query: 233 ILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGS----WM 288 +++ G P + AV +L +VG + + ++L + ++IG ++ Sbjct: 231 VVDPIGGPA-FDDAVRTLASEGRLLVVGFAAGG--IPTIKVNRLLLRNASLIGVAWGEFL 287 Query: 289 NYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP 346 + + + +L+ E + P ++ R QA++D A + GK++L+P Sbjct: 288 RTHADYLYETQAGLEKLVAEG---MRPPVSARIPLSEGRQALQDFADGKVYGKMVLVP 342 >4IDE-A nrPDB Length = 332 Score = 125 bits (315), Expect = 2e-29, Method: Composition-based stats. Identities = 63/336 (18%), Positives = 112/336 (33%), Gaps = 55/336 (16%) Query: 17 SVIPEIKHQDEVRVKIASSGLCGSDLPR---IFKNGAHYYPITLGHEFSGYIDAVGSGVD 73 +PEIK +D+V +K+ ++ L D R FK+ P G++ +G + VGS V Sbjct: 45 VAVPEIK-EDQVLIKVVAASLNPVDFKRALGYFKDTDSPLPTIPGYDVAGVVVKVGSQVT 103 Query: 74 DLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPT 133 GD V Y + + R G AEY + + P Sbjct: 104 KFKVGDEV------------------YGDLNETALVNPTRFGSLAEYTAADERVLAHKPK 145 Query: 134 DMPI-EDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLL-AIQCAVA-LGAKSVTA 190 ++ E + I A+ K+V+++G IQ A GA V A Sbjct: 146 NLSFIEAASLPLAIETAHEGLERAELSAGKSVLVLGGAGGVGTHIIQLAKHVFGASKVAA 205 Query: 191 IDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIA 250 + KL L ++ GA + ++ + + ++ + G + AV+ Sbjct: 206 TASTK-KLDLLRTLGADLAIDYTKENFEDLPEKF------DVVYDAVGET---DKAVKAV 255 Query: 251 GPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERK 310 ++ + + LT GS + P+ L K Sbjct: 256 KEGGKVVTIVGPATPPAILFV---------LTSKGSVLEKLKPY-----------LESGK 295 Query: 311 LSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP 346 + F +A + + GKV++ P Sbjct: 296 VKPVLDPTSPYPFTKVVEAFGYLESSRATGKVVVYP 331 >3FBG-A nrPDB Length = 346 Score = 125 bits (315), Expect = 2e-29, Method: Composition-based stats. Identities = 68/370 (18%), Positives = 125/370 (33%), Gaps = 61/370 (16%) Query: 1 MKSVVNDTD------GIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYP 54 +K++ + + + IPE K E+ VKI S + D + + P Sbjct: 3 LKAIGFEQPFKLSDGNLFKTFNLDIPEPKV-HEILVKIQSISVNPVDTKQRLMD-VSKAP 60 Query: 55 ITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRD 114 LG + G +++VG+ V + GD V Y ++ Sbjct: 61 RVLGFDAIGVVESVGNEVTMFNQGDIV------------------------YYSGSPDQN 96 Query: 115 GGFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHL----------AQGCENKNV 164 G AEY ++ + V P ++ E + G+ A+ E K + Sbjct: 97 GSNAEYQLINERLVAKAPKNISAEQAVSLP--LTGITAYETLFDVFGISRNRNENEGKTL 154 Query: 165 III-GAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSV 223 +II GAG +G +A Q A A G + +T + + K GA N E + Q Sbjct: 155 LIINGAGGVGSIATQIAKAYGLRVITTASRNET-IEWTKKMGADIVLNHKE--SLLNQFK 211 Query: 224 LRELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTV 283 + + + T + +++ P +A + D + K L+ Sbjct: 212 TQGIELVDYVFCTFNTDMYYDDMIQLVKPRGHIATIVAFEND-----QDLNALKPKSLSF 266 Query: 284 IGSWMNYSSPWPGQEWETASRLLTERKLSLE-----PLIAHR---GSFESFAQAVRDIAR 335 +M + L + +E P + E+ QA + + Sbjct: 267 SHEFMFARPLNQTDDMIKHHEYLEDITNKVEQNIYQPTTTKVIEGLTTENIYQAHQILES 326 Query: 336 NAMPGKVLLI 345 N M GK+++ Sbjct: 327 NTMIGKLVIN 336 >4Y1B-A nrPDB Length = 425 Score = 123 bits (310), Expect = 8e-29, Method: Composition-based stats. Identities = 68/371 (18%), Positives = 123/371 (33%), Gaps = 59/371 (15%) Query: 13 RVAESVIPEIKHQDEVRVKIASSGLCGS----------DLPRIFKNGAHYYPI-TLGHEF 61 R +P + +V VK+ ++G+ + D+ + G + Sbjct: 59 RTEVVDVPPV-GPGQVLVKVMAAGVNYNNVWAALGEPLDVIAARQKQGATEDFHIGGSDL 117 Query: 62 SGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYD--FIGSRRDGGFAE 119 SG + AVG GV L PG V + + + G + + G FA+ Sbjct: 118 SGIVWAVGDGV-RLKPGAEVVVLACRWDESAQDIRLGADPVTSSTQRVWGYEENYGSFAQ 176 Query: 120 YIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQ------GCENKNVIIIG-AGTI 172 + VV P + A + A+ V+I G AG + Sbjct: 177 FAVVDEYMCHPKPQRLSW--AAASCYMATAATAYRQLFGWEPHTVRPGDPVLIWGGAGGL 234 Query: 173 GLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMS---------------- 216 G +AIQ +G V + S E+ GA + E Sbjct: 235 GSIAIQLVRHVGGIPVAVVS-SEERGEFCMRLGAKGWIDRREFDHWGRLPDTTDEEAMKQ 293 Query: 217 --------APQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHL 268 + VL E R +++LE +G T+ ++ +A + + G Sbjct: 294 WLDGARAFGRRFWEVLGERRAPRIVLEHSGAD-TIPTSIYMADNAGMVVICG-------G 345 Query: 269 TSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQ 328 T+ G + + L + + S +E +RL+ + +++P ++ FE Sbjct: 346 TTGYNGDVDLRFLWMRQKRLQGSHAASAREAREITRLIDQG--AIDPCLSRTFGFEEIGL 403 Query: 329 AVRDIARNAMP 339 A + I N P Sbjct: 404 AHQLIHDNQHP 414 >2CF5-A nrPDB Length = 357 Score = 122 bits (307), Expect = 2e-28, Method: Composition-based stats. Identities = 71/349 (20%), Positives = 129/349 (36%), Gaps = 28/349 (8%) Query: 7 DTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKN-GAHYYPITLGHEFSGYI 65 D GI+ + E ++V ++I G+C +DL + + G YP+ GHE G + Sbjct: 17 DPSGILSPYTYTLRET-GPEDVNIRIICCGICHTDLHQTKNDLGMSNYPMVPGHEVVGEV 75 Query: 66 DAVGSGVDDLHPGD-AVACVPLLPCFTCPECLKGFYSQCAKYDFI-------GSRRDGGF 117 VGS V GD + C C C + C K + G GGF Sbjct: 76 VEVGSDVSKFTVGDIVGVGCLVGCCGGCSPCERDLEQYCPKKIWSYNDVYINGQPTQGGF 135 Query: 118 AEYIVVKRKNVFALPTDMPIEDGA--FIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLL 175 A+ VV +K V +P M +E A +TV H I+G G +G + Sbjct: 136 AKATVVHQKFVVKIPEGMAVEQAAPLLCAGVTVYSPLSHFGLKQPGLRGGILGLGGVGHM 195 Query: 176 AIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILE 235 ++ A A+G + ++ + GA S+ + + +++ Sbjct: 196 GVKIAKAMGHHVTVISSSNKKREEALQDLGADDYVIGSDQAKMSELADS-----LDYVID 250 Query: 236 TAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWP 295 T V +E + + +L L+G ++ L + ++ + GS++ Sbjct: 251 TVPVHHALEPYLSLLKLDGKLILMGVINNPLQFLTP---LLMLGRKVITGSFIGS----- 302 Query: 296 GQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 +E E E+ LS I + A + +N + + ++ Sbjct: 303 MKETEEMLEFCKEKGLSS---IIEVVKMDYVNTAFERLEKNDVRYRFVV 348 >4DVJ-A nrPDB Length = 363 Score = 119 bits (299), Expect = 2e-27, Method: Composition-based stats. Identities = 61/364 (16%), Positives = 120/364 (32%), Gaps = 50/364 (13%) Query: 1 MKSVVNDTDGIV----RVAESVIPEI-KHQDEVRVKIASSGLCGSDLPRIFKNGAHYYP- 54 MK+V + + + + +P+ ++ V++ + + D Sbjct: 23 MKAVGYNKPAPITDDASLLDIELPKPAPAGHDILVEVKAVSVNPVDYKVRRSTPPDGTDW 82 Query: 55 ITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRD 114 +G++ +G + AVG V PGD V + R Sbjct: 83 KVIGYDAAGIVSAVGPDVTLFRPGDEVFYAGSII------------------------RP 118 Query: 115 GGFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFH-------LAQGCENKN---V 164 G AE+ +V + V P + + A + + A+ + + + Sbjct: 119 GTNAEFHLVDERIVGRKPKTLDWAEAAALP--LTSITAWEAFFDRLDVNKPVPGAAPAIL 176 Query: 165 IIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVL 224 I+ GAG +G +A+Q A +V A E KS GA + S+ A ++ ++ Sbjct: 177 IVGGAGGVGSIAVQIARQRTDLTVIATASRPETQEWVKSLGAHHVIDHSKPLAAEVAAL- 235 Query: 225 RELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTV- 283 L + T + ++ P + L+ + + EL Sbjct: 236 -GLGAPAFVFSTTHTDKHAAEIADLIAPQGRFCLIDDPSAFDIMLFKRKAVSIHHELMFT 294 Query: 284 IGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGS---FESFAQAVRDIARNAMPG 340 + G+ SRL+ E + L + +R S + QA + G Sbjct: 295 RPMFGTPDMSEQGRLLNDVSRLVDEGR--LRTTLTNRLSPINAANLKQAHALVESGTARG 352 Query: 341 KVLL 344 KV++ Sbjct: 353 KVVI 356 >4A27-A nrPDB Length = 349 Score = 118 bits (297), Expect = 3e-27, Method: Composition-based stats. Identities = 63/372 (16%), Positives = 126/372 (33%), Gaps = 63/372 (16%) Query: 1 MKSVVNDTDG---IVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYY--PI 55 M++VV G +R+ +PE + E+++++ + GL DL N + P+ Sbjct: 4 MRAVVLAGFGGLNKLRLFRKAMPEPQ-DGELKIRVKACGLNFIDLMVRQGNIDNPPKTPL 62 Query: 56 TLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDG 115 G E SG ++A+G V GD V + Sbjct: 63 VPGFECSGIVEALGDSVKGYEIGDRV---------------------------MAFVNYN 95 Query: 116 GFAEYIVVKRKNVFALPTDMPIEDGAFIEP--ITVGLHAFHLAQGCENKNVII-IGAGTI 172 +AE + + V+ +P DM + A +T + F +A E +V++ G + Sbjct: 96 AWAEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVTAYVMLFEVANLREGMSVLVHSAGGGV 155 Query: 173 GLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQL 232 G Q + +VT +S A F+ + +++ + E + Sbjct: 156 GQAVAQLCSTV--PNVTVFGTASTFKHEAIKDSVTHLFDRNADYVQEVKRISAE--GVDI 211 Query: 233 ILETAGVPQTVELAVEIAGPHAQLALVG--------------TLHQDLHLTSATFGKILR 278 +L+ T + + P L G + K+ Sbjct: 212 VLDCLCGDNT-GKGLSLLKPLGTYILYGSSNMVTGETKSFFSFAKSWWQVEKVNPIKLYE 270 Query: 279 KELTVIGSWMNYSSPWPGQE------WETASRLLTERKLSLEPLIAHRGSFESFAQAVRD 332 + + G + G+ E L ++K ++P++ + E +A++ Sbjct: 271 ENKVIAGFSLLNLLFKQGRAGLIRGVVEKLIGLYNQKK--IKPVVDSLWALEEVKEAMQR 328 Query: 333 IARNAMPGKVLL 344 I GK++L Sbjct: 329 IHDRGNIGKLIL 340 >5A3V-A nrPDB Length = 329 Score = 109 bits (273), Expect = 2e-24, Method: Composition-based stats. Identities = 56/363 (15%), Positives = 116/363 (31%), Gaps = 56/363 (15%) Query: 1 MKSVVNDTDGI----VRVAESVIPEIKHQDEVRVKIASSGLCGSDLP----RIFKNGAHY 52 M ++ ++ G + + +P K +EV +K+ ++ L D I Sbjct: 6 MHALQYNSYGGGAAGLEHVQVPVPTPKS-NEVCLKLEATSLNPVDWKIQKGMIRPFLPRK 64 Query: 53 YPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSR 112 +P + +G + VGSGV + GD V V + Sbjct: 65 FPCIPATDVAGEVVEVGSGVKNFKAGDKVVAV------------------------LSHL 100 Query: 113 RDGGFAEYIVVKRKNVFALPTD--------MPIEDGAFIEPITVGLHAFHLAQGCENKNV 164 GG AE+ V K P + +P+ ++ +T L + N+ Sbjct: 101 GGGGLAEFAVATEKLTVKRPQEVGAAEAAALPVAGLTALQALTNP-AGLKLDGTGKKANI 159 Query: 165 IIIGA-GTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSV 223 ++ A G +G A+Q A A + + KS GA + + ++S Sbjct: 160 LVTAASGGVGHYAVQLAKLANAH--VTATCGARNIEFVKSLGADEVLDYKTPEGAALKSP 217 Query: 224 LRELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTV 283 + ++ A + + ++ + + + KI + + Sbjct: 218 --SGKKYDAVVHCANGI-PFSVFEPNLSENGKV--IDITPGPNAMWTYAVKKITMSKKQL 272 Query: 284 IGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVL 343 + + + E L+ E K ++ +I + A GK++ Sbjct: 273 VPLLLIP----KAENLEFMVNLVKEGK--VKTVIDSKHPLSKAEDAWAKSIDGHATGKII 326 Query: 344 LIP 346 + P Sbjct: 327 VEP 329 >2WEK-A nrPDB Length = 341 Score = 109 bits (273), Expect = 2e-24, Method: Composition-based stats. Identities = 67/348 (19%), Positives = 111/348 (31%), Gaps = 51/348 (14%) Query: 15 AESVIPEIKHQDEVRVKIASSGLCGSDLPRIFK--NGAHYYPITLGHEFSGYIDAVG-SG 71 + +P + ++ V+ G+ SD+ + + P +G E G + A+G S Sbjct: 23 RDCPVP-LPGDGDLLVRNRFVGVNASDINYSAGRYDPSVKPPFDIGFEGIGEVVALGLSA 81 Query: 72 VDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFAL 131 G AVA G FAEY VV + Sbjct: 82 SARYTVGQAVA----------------------------YMAPGSFAEYTVVPASIATPV 113 Query: 132 PTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIII-GAGTIGLLAIQCAVALGAKSVTA 190 P+ P + T + L E K V++ AG G A+Q + V Sbjct: 114 PSVKPEYLTLLVSGTTAYISLKELGGLSEGKKVLVTAAAGGTGQFAMQLSKKAKCH-VIG 172 Query: 191 IDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIA 250 S EK A KS G + N ++ E+ G +LAV+ Sbjct: 173 TCSSDEKSAFLKSLGCDRPINYKTE-PVGTVLKQEYPEGVDVVYESVGG-AMFDLAVDAL 230 Query: 251 GPHAQLALVGTLHQDLHLTSATFG-------KILRKELTVIGSWMNYSSPWPGQEWETAS 303 +L ++G + T + K+L+K +V G ++N+ Sbjct: 231 ATKGRLIVIGFISGYQTPTGLSPVKAGTLPAKLLKKSASVQGFFLNHYLSKYQAAMSHLL 290 Query: 304 RLLTERKL-------SLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 + L L P ES +AV + GK+++ Sbjct: 291 EMCVSGDLVCEVDLGDLSPE-GRFTGLESIFRAVNYMYMGKNTGKIVV 337 >3B70-A nrPDB Length = 371 Score = 108 bits (269), Expect = 4e-24, Method: Composition-based stats. Identities = 62/359 (17%), Positives = 118/359 (32%), Gaps = 59/359 (16%) Query: 17 SVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLH 76 + P + +D+V V++ + + SD + LG +++G + AVGS V + Sbjct: 29 APCPMLP-RDQVYVRVEAVAINPSDTKM--RGQFATPWAFLGTDYAGTVVAVGSDVTHIQ 85 Query: 77 PGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMP 136 GD V C + G F++Y V + + +P + Sbjct: 86 VGDRVYGAQNEMCPR-------------------TPDQGAFSQYTVTRGRVWAKIPKGLS 126 Query: 137 IEDGAFI-EPITVGLHAFHLAQ-----------GCENKNVIIIGAGT---IGLLAIQCAV 181 E A + I+ A L +K V ++ G + +Q Sbjct: 127 FEQAAALPAGISTAGLAMKLLGLPLPSPSADQPPTHSKPVYVLVYGGSTATATVTMQMLR 186 Query: 182 ALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQ 241 G + S LAKS GA + F+ + Q + + L+ + Sbjct: 187 LSGYIPIA--TCSPHNFDLAKSRGAEEVFDYRAPNLAQTIRTYTKNNL-RYALDCITNVE 243 Query: 242 TVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQE--- 298 + G V H + K++ + T+ + S WP Sbjct: 244 STTFCFAAIGRAGG-HYVSLNPFPEHAATR---KMVTTDWTLGPTIFGEGSTWPAPYGRP 299 Query: 299 ------------WETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLI 345 W A +L+ + +L PL +G F+ Q + + + + G+ L++ Sbjct: 300 GSEEERQFGEDLWRIAGQLVEDGRLVHHPLRVVQGGFDHIKQGMELVRKGELSGEKLVV 358 >3SLK-A nrPDB Length = 795 Score = 106 bits (264), Expect = 2e-23, Method: Composition-based stats. Identities = 64/343 (18%), Positives = 108/343 (31%), Gaps = 50/343 (14%) Query: 9 DGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPIT--LGHEFSGYID 66 DG+ V E EVR+ + ++G+ D YP LG E +G + Sbjct: 222 DGLALVDEPTATAPLGDGEVRIAMRAAGVNFRDALIALG----MYPGVASLGSEGAGVVV 277 Query: 67 AVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRK 126 G GV L PGD V F V + Sbjct: 278 ETGPGVTGLAPGDRVMG----------------------------MIPKAFGPLAVADHR 309 Query: 127 NVFALPTDMPIEDGAFIEP--ITVGLHAFHLAQGCENKNVII-IGAGTIGLLAIQCAVAL 183 V +P A + +T LA +++++ AG +G+ AIQ A L Sbjct: 310 MVTRIPAGWSFARAASVPIVFLTAYYALVDLAGLRPGESLLVHSAAGGVGMAAIQLARHL 369 Query: 184 GAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTV 243 GA+ S +K A +S Q R ++L + Sbjct: 370 GAE--VYATASEDKWQ-AVELSREHLASSRTCDFEQQFLGATGGRGVDVVLNSLAGEFA- 425 Query: 244 ELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETAS 303 + ++ + + +G + A V + P + E Sbjct: 426 DASLRMLPRGGRFLELGKTDVRDPVEVADAHP------GVSYQAFDTVEAGPQRIGEMLH 479 Query: 304 RLLT--ERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 L+ E ++ LEPL +A+R +++ GK++L Sbjct: 480 ELVELFEGRV-LEPLPVTAWDVRQAPEALRHLSQARHVGKLVL 521 >2VWH-A nrPDB Length = 357 Score = 103 bits (257), Expect = 1e-22, Method: Composition-based stats. Identities = 66/355 (18%), Positives = 118/355 (33%), Gaps = 35/355 (9%) Query: 1 MKSVVNDTDGIVRVA-ESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYP----- 54 MK++ V E PE + E V+ G+ G+D + G +P Sbjct: 1 MKAIAVKRGEDRPVVIEKPRPEPES-GEALVRTLRVGVDGTD-HEVIAGGHGGFPEGEDH 58 Query: 55 ITLGHEFSGYIDAVGSGVDDLHPGDAVA--CVPLLPCFTCPECLKGFYSQCAKYDFIGSR 112 + LGHE G + +L GD V T + + Sbjct: 59 LVLGHEAVGVVVD--PNDTELEEGDIVVPTVRRPPASGTNEYFERDQPDMAPDGMYFERG 116 Query: 113 RDGG---FAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCEN------KN 163 G +E+ K + +P E G IEPI++ A A + + Sbjct: 117 IVGAHGYMSEFFTSPEKYLVRIPRSQA-ELGFLIEPISITEKALEHAYASRSAFDWDPSS 175 Query: 164 VIIIGAGTIGLLAIQCAVA--LGAKSVTAIDISSE---KLALAKSFGAMQTFNSSEMSAP 218 ++G G++GLL + G +++ + + + + A +S + Sbjct: 176 AFVLGNGSLGLLTLAMLKVDDKGYENLYCLGRRDRPDPTIDIIEELDATY-VDSRQTPVE 234 Query: 219 QMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILR 278 + V ++ I E G P+ +V+ P+ AL+G A Sbjct: 235 DVPDVYEQM---DFIYEATGFPKHAIQSVQALAPNGVGALLGVPSDWAFEVDAG---AFH 288 Query: 279 KELTVIGSWMNYSSPWPGQEWETASRLLTE-RKLSLEPLIAHRGSFESFAQAVRD 332 +E+ + + S + +E A+ T+ K LE L+ F A D Sbjct: 289 REMVLHNKALVGSVNSHVEHFEAATVTFTKLPKWFLEDLVTGVHPLSEFEAAFDD 343 >5LB9-A nrPDB Length = 385 Score = 96.2 bits (238), Expect = 2e-20, Method: Composition-based stats. Identities = 71/351 (20%), Positives = 110/351 (31%), Gaps = 52/351 (14%) Query: 25 QDEVRVKIASSGLCGSDLPRIFKNGAHYY----------PITL-GHEFSGYIDAVGSGVD 73 +EV VK S + SD+ +I P G+E + VGS V Sbjct: 54 PNEVIVKTLGSPVNPSDINQIQGVYPSKPAKTTGFGTTEPAAPCGNEGLFEVIKVGSNVS 113 Query: 74 DLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPT 133 L GD V + T G K + G P Sbjct: 114 SLEAGDWV-IPSHVNFGTWRTHALGNDDDFIKLPNPAQSKANG--------------KPN 158 Query: 134 DMPIEDGAFIE--PITVGLHAFHLAQGCENKNVIIIGAG--TIGLLAIQCAVALGAKSVT 189 + I GA I P+ L H + K+ I G +G A Q L S++ Sbjct: 159 GLTINQGATISVNPLVAYLMLTHYVKLTPGKDWFIQNGGTSAVGKYASQIGKLLNFNSIS 218 Query: 190 AIDISS---EKLALAKSFGAMQTF----NSSEMSAPQMQSVLRELRF-NQLILETAGVPQ 241 I E +A K GA Q N+S P ++ +++ +L L G Sbjct: 219 VIRDRPNLDEVVASLKELGATQVITEDQNNSREFGPTIKEWIKQSGGEAKLALNCVGGKS 278 Query: 242 TVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMN----YSSPWPGQ 297 + +A ++ L G Q + + ++ + + K T G W+ + Sbjct: 279 STGIARKLNNNGLMLTYGGMSFQPVTIPTSLY---IFKNFTSAGFWVTELLKNNKELKTS 335 Query: 298 EWETASRLLTERKL----SLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 E KL S+E L +D N+ GK L+ Sbjct: 336 TLNQIIAWYEEGKLTDAKSIETLYDGTKPLHEL---YQDGVANSKDGKQLI 383 >2CDC-A nrPDB Length = 366 Score = 90.1 bits (222), Expect = 1e-18, Method: Composition-based stats. Identities = 62/365 (16%), Positives = 122/365 (33%), Gaps = 36/365 (9%) Query: 1 MKSVVNDTDGI-VRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGA-HYYP---- 54 MK+++ V+V + ++ +++++ +G+CG+D + P Sbjct: 1 MKAIIVKPPNAGVQVKDVDEKKLDSYGKIKIRTIYNGICGADREIVNGKLTLSTLPKGKD 60 Query: 55 -ITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDF---IG 110 + LGHE G ++ GD V V C C CL G C +F Sbjct: 61 FLVLGHEAIGVVEE---SYHGFSQGDLVMPVNRRGCGICRNCLVGRPDFCETGEFGEAGI 117 Query: 111 SRRDGGFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCEN--------- 161 + DG E+ K + +P + + G +P+ + + Sbjct: 118 HKMDGFMREWWYDDPKYLVKIPKSI-EDIGILAQPLADIEKSIEEILEVQKRVPVWTCDD 176 Query: 162 -----KNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLAL-AKSFGAMQTFNSSEM 215 + V+++G G IG+L G + A ++ +NSS Sbjct: 177 GTLNCRKVLVVGTGPIGVLFTLLFRTYGLEVWMANRREPTEVEQTVIEETKTNYYNSSNG 236 Query: 216 SAPQMQSVLRELRFNQLILETAGVPQTV-ELAVEIAGPHAQLALVGT-LHQDLHLTSATF 273 + + +I++ G + + + G + L L G + L T Sbjct: 237 ----YDKLKDSVGKFDVIIDATGADVNILGNVIPLLGRNGVLGLFGFSTSGSVPLDYKTL 292 Query: 274 GKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDI 333 +I+ T+IG +N P Q + T + + LI S + ++ + Sbjct: 293 QEIVHTNKTIIG-LVNGQKPHFQQAVVHLASWKTLYPKAAKMLITKTVSINDEKELLKVL 351 Query: 334 ARNAM 338 Sbjct: 352 REKEH 356 >1V3V-A nrPDB Length = 333 Score = 87.4 bits (215), Expect = 8e-18, Method: Composition-based stats. Identities = 37/229 (16%), Positives = 77/229 (33%), Gaps = 13/229 (5%) Query: 125 RKNVFALPTDMPIEDG---AFIEPITVGLHAFHLAQGCENKNVIIIGA-GTIGLLAIQCA 180 K + P +P+ + +T + + V++ A G +G + Q A Sbjct: 107 EKLLTEWPDKLPLSLALGTIGMPGLTAYFGLLEVCGVKGGETVLVSAAAGAVGSVVGQIA 166 Query: 181 VALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVP 240 G K V S EK+A K G FN +++ + + G Sbjct: 167 KLKGCK-VVGAAGSDEKIAYLKQIGFDAAFNYKTVNSLEEALKKASPDGYDCYFDNVGG- 224 Query: 241 QTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGK----ILRKELTVIGSWM-NYSSPWP 295 + + + ++A+ G + + G I+ K+L + G + + Sbjct: 225 EFLNTVLSQMKDFGKIAICGAISVYNRMDQLPPGPSPESIIYKQLRIEGFIVYRWQGDVR 284 Query: 296 GQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 + + + E K+ + FE+ A ++ A GK ++ Sbjct: 285 EKALRDLMKWVLEGKIQYHEHVTK--GFENMPAAFIEMLNGANLGKAVV 331 >1O89-A nrPDB Length = 345 Score = 85.4 bits (210), Expect = 3e-17, Method: Composition-based stats. Identities = 59/331 (17%), Positives = 100/331 (30%), Gaps = 45/331 (13%) Query: 24 HQDEVRVKIASSGLCGSDLPRIFKNGAHY--YPITLGHEFSGYIDAVGSGVDDLHPGDAV 81 + +V V + S L D I G +P+ G +F+G + S H G V Sbjct: 47 PEGDVTVDVHWSSLNYKDALAITGKGKIIRNFPMIPGIDFAGTVRT--SEDPRFHAGQEV 104 Query: 82 ACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGA 141 +G GG AE VK + A+P + Sbjct: 105 LLTGWG---------------------VGENHWGGLAEQARVKGDWLVAMPQGLDARKAM 143 Query: 142 FIEPITVGLHA------FHLAQGCE--NKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDI 193 I T G A A + V+ +G +G A+ LG V A+ Sbjct: 144 IIG--TAGFTAMLCVMALEDAGVRPQDGEIVVTGASGGVGSTAVALLHKLG-YQVVAVSG 200 Query: 194 SSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPH 253 KS GA + + A E + ++T G + + + Sbjct: 201 RESTHEYLKSLGASRVL-PRDEFAESRPL---EKQVWAGAIDTVG-DKVLAKVLAQMNYG 255 Query: 254 AQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSL 313 +A G T+ + + + + G ++ P + + RL+ + S Sbjct: 256 GCVAACGLAGGFTLPTT--VMPFILRNVRLQG--VDSVMTPPERRAQAWQRLVADLPESF 311 Query: 314 EPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 A S I N + G+ L+ Sbjct: 312 YTQAAKEISLSEAPNFAEAIINNQIQGRTLV 342 >5GXF-A nrPDB Length = 330 Score = 75.0 bits (183), Expect = 5e-14, Method: Composition-based stats. Identities = 59/327 (18%), Positives = 103/327 (31%), Gaps = 39/327 (11%) Query: 26 DEVRVKIASSGLCGSDLPRIFKNGAH--YYPITLGHEFSGYIDAVGSGVDDLHPGDAVAC 83 EV V + S + D I G YP G +F+G ++ S + PGD V Sbjct: 31 GEVTVAVEYSTVNYKDGLCIGPGGGLVRKYPHVPGIDFAGTVEN--SSDERYKPGDKVVL 88 Query: 84 VPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAFI 143 +G GG+++ V+ + LP + + Sbjct: 89 TGWR---------------------VGEAHWGGYSQKANVRADWLVPLPEGLDTRQAMAV 127 Query: 144 --EPITV--GLHAFHLAQGCENK-NVIIIG-AGTIGLLAIQCAVALGAKSVTAIDISSEK 197 T + A V++ G AG +G +A LG V A+ E Sbjct: 128 GTAGFTAMLAVMALEDHGLTPGHGPVLVTGAAGGVGSVATAILAHLG-YEVAAVTGRPET 186 Query: 198 LALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLA 257 S GA Q + + ++ L E ++ G + ++ + A Sbjct: 187 ADYLTSLGATQIV-ARDEINETVKRPL-ESEIWAGCVDAVGGAMLARVLGQMKYGASVAA 244 Query: 258 LVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLI 317 + L T F L + Y++ + WE +R L KL + Sbjct: 245 VGLAGGAGLPATVIPFLLRGVNLLGIDSVMQPYANR--LRAWERIARDLPMDKLEA---M 299 Query: 318 AHRGSFESFAQAVRDIARNAMPGKVLL 344 + DI + + G+V++ Sbjct: 300 IRPATLSDLPGLGADILKGQVQGRVVV 326 >3WID-A nrPDB Length = 369 Score = 73.9 bits (180), Expect = 8e-14, Method: Composition-based stats. Identities = 62/368 (16%), Positives = 123/368 (33%), Gaps = 44/368 (11%) Query: 4 VVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYP------ITL 57 V + G V+ + +PE + E ++K G+CG+D + + Y + L Sbjct: 8 VTDAPKGGVKYTKIDMPEPEK-YEAKLKPVYIGICGTDRGEVAGALSFTYNPEGENFLVL 66 Query: 58 GHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQC----AKYDFIGSRR 113 GHE + V S + + GD V + P C C G C G Sbjct: 67 GHEALLQVLDV-SDNNYIKRGDFVVPLVRRP-GKCVNCRIGRQDNCSIGDPDKHEAGITG 124 Query: 114 DGGFAEYIVVKR-KNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCE------------ 160 GF ++ +N+ + + EP+ + AF + Sbjct: 125 LHGFMRDVIYDDIQNLVKVNDPDLGKIAVLTEPLKNVMKAFEVFDVVSKRSIFQNDDSTF 184 Query: 161 -NKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQ 219 K +++IG+G+ L G VT ++ E K + Sbjct: 185 IGKKMVVIGSGSEAFLYSFVGKDRG-FDVTMVNRHDETENKMKMM---------DDFGVG 234 Query: 220 MQSVLRELRF-NQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTS--ATFGKI 276 + L+++ L+++T+G P T+ V+ + + L G + I Sbjct: 235 FSNYLKDMPDKIDLLVDTSGDPSTIFKFVKKVNNNGVVILFGFNGKAPGYPVNGEDIDYI 294 Query: 277 LRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARN 336 + + +T+ GS + Q ++ S +++ +I + E + Sbjct: 295 VERNITIAGSVDAAKIHY-VQALDSLSNWYHRHPQTIKDIITYEAKPEETN---IFFQKP 350 Query: 337 AMPGKVLL 344 K ++ Sbjct: 351 KGEIKTVI 358 >2Y05-A nrPDB Length = 328 Score = 72.3 bits (176), Expect = 3e-13, Method: Composition-based stats. Identities = 34/229 (14%), Positives = 75/229 (32%), Gaps = 13/229 (5%) Query: 125 RKNVFALPTDMPIEDG---AFIEPITVGLHAFHLAQGCENKNVII-IGAGTIGLLAIQCA 180 K + P +P+ + +T + + V++ AG +G + Q A Sbjct: 102 EKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIA 161 Query: 181 VALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVP 240 G K V A+ S EK+A + G FN + + + + G Sbjct: 162 KLKGCKVVGAVG-SDEKVAYLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGE 220 Query: 241 QTVELAVEIAGPHAQLALVGTLH----QDLHLTSATFGKILRKELTVIGSWM-NYSSPWP 295 + + ++A+ G + ++ +EL + + + Sbjct: 221 FS-NTVIGQMKKFGRIAICGAISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDAR 279 Query: 296 GQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 + + + + E K+ + I FE+ A + + GK ++ Sbjct: 280 QKALKDLLKWVLEGKIQYKEYII--EGFENMPAAFMGMLKGDNLGKTIV 326 >2J3K-A nrPDB Length = 345 Score = 71.6 bits (174), Expect = 5e-13, Method: Composition-based stats. Identities = 38/208 (18%), Positives = 71/208 (34%), Gaps = 9/208 (4%) Query: 143 IEPITVGLHAFHLAQGCENKNVIIIGA-GTIGLLAIQCAVALGAKSVTAIDISSEKLALA 201 + +T + + E + V + A G +G L Q A +G V S EK+ L Sbjct: 138 MPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCY-VVGSAGSKEKVDLL 196 Query: 202 K-SFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALVG 260 K FG FN E S + E G + ++ + H ++A+ G Sbjct: 197 KTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGG-KMLDAVLVNMNMHGRIAVCG 255 Query: 261 TLHQ---DLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLI 317 + Q + I+ K + G ++ + E + E K + + Sbjct: 256 MISQYNLENQEGVHNLSNIIYKRNRIQGFVVSDFYDKYSKFLEFVLPHIREGK--ITYVE 313 Query: 318 AHRGSFESFAQAVRDIARNAMPGKVLLI 345 E +A+ + GK +++ Sbjct: 314 DVADGLEKAPEALVGLFHGKNVGKQVVV 341 >2ZB3-A nrPDB Length = 353 Score = 57.7 bits (138), Expect = 6e-09, Method: Composition-based stats. Identities = 56/355 (15%), Positives = 103/355 (29%), Gaps = 58/355 (16%) Query: 13 RVAESVIPEIKHQDEVRVKIASSGL-----C------GSDLPRIFKNGAHYYPITLGHEF 61 RV E +P+ ++ +V+V+ + C G+D ++ Sbjct: 26 RVEEFSLPDALNEGQVQVRTLYLSVDPYMRCKMNEDTGTDYLAPWQLAQVADGG-----G 80 Query: 62 SGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYI 121 G ++ S L GD V + L G + K D DG + Y Sbjct: 81 IGVVEE--SKHQKLTKGDFVTSFYWP--WQTKAILDG--NGLEKVDP--QLVDGHLS-YF 131 Query: 122 VVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKN---VIIIGAGTIGLLAIQ 178 + + +T + N V+ AG G LA Q Sbjct: 132 L----------------GAIGMPGLTSLIGVQEKGHISAGSNQTMVVSGAAGACGSLAGQ 175 Query: 179 CAVALGAKSVTAI-DISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETA 237 LG V I + L L G N + + + + Sbjct: 176 IGHLLGCSRVVGICGTQEKCLFLTSELGFDAAVNYKTGNVAEQLREACPG-GVDVYFDNV 234 Query: 238 GVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATF-----GKILRKELTV---IGSWMN 289 G + + ++ + L G + Q + + +RKE + + +N Sbjct: 235 GGDIS-NAVISQMNENSHIILCGQISQYSNDVPYPPPLPPAVEAIRKERNITRERFTVLN 293 Query: 290 YSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 Y + S+ E KL ++ E+ A + + GK ++ Sbjct: 294 YKDKFEPG-ILQLSQWFKEGKLKVKE--TMAKGLENMGVAFQSMMTGGNVGKQIV 345 >2VNA-A nrPDB Length = 357 Score = 56.9 bits (136), Expect = 1e-08, Method: Composition-based stats. Identities = 53/351 (15%), Positives = 106/351 (30%), Gaps = 50/351 (14%) Query: 13 RVAESVIPEIKHQDEVRVKIASSGL-----CG--SDLPRIFKNGAHYYPITLGHEFSGYI 65 R+ E +P+ ++ +V+V+ + C D + + G G I Sbjct: 25 RMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDTGTDYITPWQLSQVVDG-GGIGII 83 Query: 66 DAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKR 125 + S +L GD V + L G + K D DG + Y + Sbjct: 84 EE--SKHTNLTKGDFVTSFYWP--WQTKVILDG--NSLEKVDP--QLVDGHLS-YFL--- 131 Query: 126 KNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKN---VIIIGAGTIGLLAIQCAVA 182 + +T + N V+ AG G +A Q Sbjct: 132 -------------GAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHF 178 Query: 183 LGAKSVTAI-DISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQ 241 LG V I + + L G N + + + + + G Sbjct: 179 LGCSRVVGICGTHEKCILLTSELGFDAAINYKKDNVAEQLRESCP-AGVDVYFDNVGGNI 237 Query: 242 TVELAVEIAGPHAQLALVGTLHQ-----DLHLTSATFGKILRKELTV---IGSWMNYSSP 293 + + + ++ + L G + Q + + ++KE + +NY Sbjct: 238 S-DTVISQMNENSHIILCGQISQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYKDK 296 Query: 294 WPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLL 344 + S+ E KL ++ + + E+ A + + GK ++ Sbjct: 297 FEPG-ILQLSQWFKEGKLKIKETVIN--GLENMGAAFQSMMTGGNIGKQIV 344 >3MGG-A nrPDB Length = 276 Score = 41.1 bits (95), Expect = 6e-04, Method: Composition-based stats. Identities = 24/162 (14%), Positives = 49/162 (30%), Gaps = 7/162 (4%) Query: 160 ENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQ 219 V+ G G IG + A +T+IDIS E L A+ + + Sbjct: 37 PGAKVLEAGCG-IGAQTVILAKNNPDAEITSIDISPESLEKARENTEKNGIKNVKFLQAN 95 Query: 220 MQSVLRELRFNQLILET------AGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATF 273 + S+ E I + ++ ++ P + ++ H + Sbjct: 96 IFSLPFEDSSFDHIFVCFVLEHLQSPEEALKSLKKVLKPGGTITVIEGDHGSCYFHPEGK 155 Query: 274 GKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEP 315 I + + G++ + K+ +EP Sbjct: 156 KAIEAWNCLIRVQAYMKGNSLVGRQIYPLLQESGFEKIRVEP 197 >1X14-A nrPDB Length = 401 Score = 40.4 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 39/184 (21%), Positives = 65/184 (35%), Gaps = 25/184 (13%) Query: 155 LAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQT-FNSS 213 A V++IGAG GL AI A +LGA V A D E +S GA + Sbjct: 166 AAGKVPPAKVMVIGAGVAGLAAIGAANSLGA-IVRAFDTRPEVKEQVQSMGAEFLELDFK 224 Query: 214 EMS---------------APQMQSVLRELRFNQLILETA---GVPQTVELAVEIAGPH-- 253 E + +M+ + + +I+ TA G P + E+ Sbjct: 225 EEAGSGDGYAKVMSDAFIKAEMELFAAQAKEVDIIVTTALIPGKPAPKLITREMVDSMKA 284 Query: 254 AQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSL 313 + + + G+I E G + + PG+ +S+L ++L Sbjct: 285 GSVIVDLAAQNGGNCEYTVPGEIFTTE---NGVKVIGYTDLPGRLPTQSSQLYGTNLVNL 341 Query: 314 EPLI 317 L+ Sbjct: 342 LKLL 345 >1XLT-A nrPDB Length = 384 Score = 39.2 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 39/182 (21%), Positives = 66/182 (36%), Gaps = 28/182 (15%) Query: 155 LAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGA------MQ 208 A V++ G G GL AI A LGA V A D+ + +S G + Sbjct: 166 AAGTVPPARVLVFGVGVAGLQAIATAKRLGA-VVMATDVRAATKEQVESLGGKFITVDDE 224 Query: 209 TFNSSEMS------------APQMQSVLRELRFNQLILETA---GVPQTVELAVEIAGPH 253 ++E + Q ++VL+EL + + TA G P V + E+ Sbjct: 225 AMKTAETAGGYAKEMGEEFRKKQAEAVLKELVKTDIAITTALIPGKPAPVLITEEMVTKM 284 Query: 254 --AQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKL 311 + + + + + GKI+ K G + + P + AS L + L Sbjct: 285 KPGSVIIDLAVEAGGNCPLSEPGKIVVK----HGVKIVGHTNVPSRVAADASPLFAKNLL 340 Query: 312 SL 313 + Sbjct: 341 NF 342 >2BRY-A nrPDB Length = 497 Score = 38.8 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 23/101 (22%), Positives = 38/101 (37%), Gaps = 12/101 (11%) Query: 92 CPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDM--PIEDGAFIEPITVG 149 C + L F C +G GG ++Y +K + + + ++ A Sbjct: 31 CQDVLSSFQGLCRA---LGVESGGGLSQYHKIKAQLNYWSAKSLWAKLDKRASQP----- 82 Query: 150 LHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTA 190 + Q C N +++GAG GL A LGA+ V Sbjct: 83 --VYQQGQACTNTKCLVVGAGPCGLRAAVELALLGARVVLV 121 >4TXK-A nrPDB Length = 615 Score = 38.4 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 23/101 (22%), Positives = 38/101 (37%), Gaps = 12/101 (11%) Query: 92 CPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDM--PIEDGAFIEPITVG 149 C + L F C +G GG ++Y +K + + + ++ A Sbjct: 23 CQDVLSSFQGLCRA---LGVESGGGLSQYHKIKAQLNYWSAKSLWAKLDKRASQP----- 74 Query: 150 LHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTA 190 + Q C N +++GAG GL A LGA+ V Sbjct: 75 --VYQQGQACTNTKCLVVGAGPCGLRAAVELALLGARVVLV 113 >2EGU-A nrPDB Length = 308 Score = 36.9 bits (84), Expect = 0.011, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 25/78 (32%), Gaps = 2/78 (2%) Query: 152 AFHLAQGCENKNVI--IIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQT 209 A + ++ G IGL + A A V +S E+ L +++GA Sbjct: 56 AEKAGKLKPGDTIVEPTSGNTGIGLAMVAAAKGYKAVLVMPDTMSLERRNLLRAYGAELV 115 Query: 210 FNSSEMSAPQMQSVLREL 227 + EL Sbjct: 116 LTPGAQGMRGAIAKAEEL 133 >4DIO-A nrPDB Length = 405 Score = 36.9 bits (84), Expect = 0.012, Method: Composition-based stats. Identities = 23/93 (24%), Positives = 33/93 (35%), Gaps = 8/93 (8%) Query: 155 LAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSE 214 A + ++GAG GL AI A LGA V+A D+ S GA Sbjct: 184 AAGTVPAAKIFVMGAGVAGLQAIATARRLGA-VVSATDVRPAAKEQVASLGAKFI----- 237 Query: 215 MSAPQMQSVLRELRFNQLILETAGVPQTVELAV 247 A + + E +G Q + A+ Sbjct: 238 --AVEDEEFKAAETAGGYAKEMSGEYQVKQAAL 268 >4XIJ-A nrPDB Length = 275 Score = 36.9 bits (84), Expect = 0.014, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 25/63 (39%), Gaps = 4/63 (6%) Query: 148 VGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEK----LALAKS 203 + A G + ++IG+G A+ LG + +T + K + LA+ Sbjct: 113 TDVDGVTGALGTAGDSALVIGSGGTAPAAVVALAELGVQRITIVARDEGKASRLVDLARR 172 Query: 204 FGA 206 GA Sbjct: 173 CGA 175 >1ZCJ-A nrPDB Length = 463 Score = 36.5 bits (83), Expect = 0.016, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 25/53 (47%), Gaps = 3/53 (5%) Query: 153 FHLAQGCENKNVIIIGAGTIGL-LAIQCAVALGAKSVTAIDISSEKLALAKSF 204 + A +V ++G GT+G +AI A SV A++ ++L AK Sbjct: 29 WKTASAQPVSSVGVLGLGTMGRGIAISFARV--GISVVAVESDPKQLDAAKKI 79 >1CYD-A nrPDB Length = 244 Score = 36.5 bits (83), Expect = 0.019, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 30/76 (39%), Gaps = 1/76 (1%) Query: 161 NKNVIIIGAG-TIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQ 219 ++ GAG IG ++ A GAK V +S+ ++LAK ++ Sbjct: 7 GLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPGIEPVCVDLGDWDA 66 Query: 220 MQSVLRELRFNQLILE 235 + L + L++ Sbjct: 67 TEKALGGIGPVDLLVN 82 >5F8E-A nrPDB Length = 377 Score = 36.1 bits (82), Expect = 0.020, Method: Composition-based stats. Identities = 23/108 (21%), Positives = 36/108 (33%), Gaps = 6/108 (5%) Query: 157 QGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKL----ALAKSFG-AMQTFN 211 + +V G G+ G A A GA T ID S E + A G A TF Sbjct: 184 RLRSGADVADFGCGS-GRAVKLMAQAFGASRFTGIDFSDEAVAAGTEEAARLGLANATFE 242 Query: 212 SSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALV 259 +++ + I + A + ++ P L +V Sbjct: 243 RHDLAELDKVGAYDVITVFDAIHDQAQPARVLQNIYRALRPGGVLLMV 290 >1W1U-A nrPDB Length = 557 Score = 36.1 bits (82), Expect = 0.020, Method: Composition-based stats. Identities = 15/106 (14%), Positives = 31/106 (29%), Gaps = 4/106 (3%) Query: 154 HLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSS 213 H + K V+ G G +G A GA S+ I+ ++ + + Sbjct: 160 HYGGSLKGKWVLTAGLGGMGGAQPLAATLAGACSLN-IESQQSRIDFRLE---TRYVDEQ 215 Query: 214 EMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALV 259 + + + A E+ E+ + +V Sbjct: 216 ATDLDDALVRIAKYTAEGKAISIALHGNAAEILPELVKRGVRPDMV 261 >6BII-A nrPDB Length = 333 Score = 36.1 bits (82), Expect = 0.021, Method: Composition-based stats. Identities = 13/47 (27%), Positives = 17/47 (36%), Gaps = 2/47 (4%) Query: 161 NKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAM 207 K + I+G G IG + A G + S K K GA Sbjct: 150 GKTIGIVGFGRIGQAIAKRAKGFGMR--ILYTARSRKPEAEKELGAE 194 >5UYY-A nrPDB Length = 381 Score = 36.1 bits (82), Expect = 0.024, Method: Composition-based stats. Identities = 37/168 (22%), Positives = 59/168 (35%), Gaps = 13/168 (7%) Query: 162 KNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQ 221 K V++IG G IG ++T DI E++ AK + A +Q Sbjct: 18 KKVVLIGTGLIGGSLALAIKKDHDVTITGYDIFQEQVERAKEL---HVV---DEIAVDLQ 71 Query: 222 SVLRELRFNQLILETAGVPQTVELAVEIAGPHAQL-ALVGTLHQDLHLTSATFGKILRKE 280 E LI+ + V +T +L ++A H + +V + + KE Sbjct: 72 HACEE---AHLIVFASPVEETKKLLHKLASFHLREDVIVTDVGSTKGSIMNEAEALFSKE 128 Query: 281 LTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQ 328 ++ IG S G E A L L P+ H E + Sbjct: 129 ISFIGGHPMAGSHKTGVESAKA-HLFENAFYILTPM--HHVPNEHVEE 173 >3ZWA-A nrPDB Length = 742 Score = 35.8 bits (81), Expect = 0.029, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 25/53 (47%), Gaps = 3/53 (5%) Query: 153 FHLAQGCENKNVIIIGAGTIGL-LAIQCAVALGAKSVTAIDISSEKLALAKSF 204 + A +V ++G GT+G +AI A SV A++ ++L AK Sbjct: 308 WKTASAQPVSSVGVLGLGTMGRGIAISFARV--GISVVAVESDPKQLDAAKKI 358 >3VPX-A nrPDB Length = 364 Score = 35.8 bits (81), Expect = 0.029, Method: Composition-based stats. Identities = 14/51 (27%), Positives = 21/51 (41%), Gaps = 2/51 (3%) Query: 160 ENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALA-KSFGAMQT 209 K V + G G + + GAK + DI+ E + A +FGA Sbjct: 172 AGKTVAVQGVGNVAYALCEYLHEEGAKLII-TDINEEAVQRAVDAFGATAV 221 >5D84-A nrPDB Length = 326 Score = 35.8 bits (81), Expect = 0.030, Method: Composition-based stats. Identities = 17/60 (28%), Positives = 25/60 (41%), Gaps = 2/60 (3%) Query: 151 HAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAID--ISSEKLALAKSFGAMQ 208 H EN ++I +G +G+ A G K +D IS L + KS+GA Sbjct: 57 HGIKHGLITENTHLIESTSGNLGIALAMIAKIKGLKLTCVVDPKISPTNLKIIKSYGANV 116 >2E84-A nrPDB Length = 556 Score = 35.0 bits (79), Expect = 0.045, Method: Composition-based stats. Identities = 27/127 (21%), Positives = 36/127 (28%), Gaps = 19/127 (14%) Query: 68 VGSGVDDLHPGDAVACVPLL--------PCFTCPECLKGFYSQCAKYDFIGSRRDGGFAE 119 VG G D G A P+ TC C C + +DG F Sbjct: 284 VGPGAKDTPKGMKGAMKPVAFNHKVHEAASNTCRACHHVKIDNCTTCHTLEGVKDGNF-- 341 Query: 120 YIVVKRKNVFALPTDMPIEDGA----FIEPITVGLHAFHL--AQGCENKNVIIIGAGTIG 173 V+ + P M G P G H F A+ + A +G Sbjct: 342 ---VQIEKAMHQPDSMKSCVGCHNQKVQAPACAGCHGFMKTGAKPQPEAACGVCHADPVG 398 Query: 174 LLAIQCA 180 + A A Sbjct: 399 MDAKTVA 405 >5EKU-A nrPDB Length = 390 Score = 35.0 bits (79), Expect = 0.047, Method: Composition-based stats. Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 9/70 (12%) Query: 158 GCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSA 217 V+ IGAG+ GLL++ A LGAK V A++ S E LA+ N + Sbjct: 93 VTPETGVLEIGAGS-GLLSLMAAK-LGAKWVVAVEGSEELAKLARE-------NIRANNM 143 Query: 218 PQMQSVLREL 227 VL + Sbjct: 144 EHQVKVLHMM 153 >4M36-A nrPDB Length = 343 Score = 35.0 bits (79), Expect = 0.047, Method: Composition-based stats. Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 9/70 (12%) Query: 158 GCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSA 217 V+ IGAG+ GLL++ A LGAK V A++ S E LA+ N + Sbjct: 58 VTPETGVLEIGAGS-GLLSLMAAK-LGAKWVVAVEGSEELAKLARE-------NIRANNM 108 Query: 218 PQMQSVLREL 227 VL + Sbjct: 109 EHQVKVLHMM 118 >1BW9-B nrPDB Length = 356 Score = 35.0 bits (79), Expect = 0.050, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 22/58 (37%), Gaps = 1/58 (1%) Query: 152 AFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQT 209 A + V++ G G +G A GA + D +E++A A + G Sbjct: 167 AHRGLGSLDGLTVLVQGLGAVGGSLASLAAEAGA-QLLVADTDTERVAHAVALGHTAV 223 >3D2L-A nrPDB Length = 243 Score = 34.6 bits (78), Expect = 0.062, Method: Composition-based stats. Identities = 28/113 (24%), Positives = 44/113 (38%), Gaps = 12/113 (10%) Query: 152 AFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAM---- 207 A+ L Q K + IG GT G + A VT +D+S E L +A+ Sbjct: 25 AWVLEQVEPGKRIADIGCGT-GTATLLLADHY---EVTGVDLSEEMLEIAQEKAMETNRH 80 Query: 208 ---QTFNSSEMSAPQMQSVLRELRFNQLILET-AGVPQTVELAVEIAGPHAQL 256 + E+ P+ + L + L+T A V QT + A + +L Sbjct: 81 VDFWVQDMRELELPEPVDAITILCDSLNYLQTEADVKQTFDSAARLLTDGGKL 133 >1XDW-A nrPDB Length = 331 Score = 34.6 bits (78), Expect = 0.069, Method: Composition-based stats. Identities = 22/118 (18%), Positives = 41/118 (34%), Gaps = 15/118 (12%) Query: 150 LHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEK--LALAKSFGAM 207 + AF ++ N V ++G G IG +A Q +GA +V D+ K Sbjct: 135 VDAFMFSKEVRNCTVGVVGLGRIGRVAAQIFHGMGA-TVIGEDVFEIKGIEDYCTQVSLD 193 Query: 208 QTFN-----------SSEMSAPQMQSVLRELRFNQLILETA-GVPQTVELAVEIAGPH 253 + E A + L++++ +++ A G E +E Sbjct: 194 EVLEKSDIITIHAPYIKENGAVVTRDFLKKMKDGAILVNCARGQLVDTEAVIEAVESG 251 >2B25-A nrPDB Length = 336 Score = 34.2 bits (77), Expect = 0.076, Method: Composition-based stats. Identities = 19/108 (17%), Positives = 43/108 (39%), Gaps = 17/108 (15%) Query: 158 GCENKNVIIIGAGTIGLLAIQCAVALGA-KSVTAIDISSEKLALAKSFGAMQTFNSSEMS 216 V+ G+G+ G +++ + A+G+ V + ++ + LAK N Sbjct: 103 INPGDTVLEAGSGS-GGMSLFLSKAVGSQGRVISFEVRKDHHDLAKK-------NYKHWR 154 Query: 217 APQMQSVLRELRFNQLIL--ETAGVPQTVE------LAVEIAGPHAQL 256 S + E N + + +G + ++ +A+++ PH L Sbjct: 155 DSWKLSHVEEWPDNVDFIHKDISGATEDIKSLTFDAVALDMLNPHVTL 202 >1V9L-A nrPDB Length = 421 Score = 34.2 bits (77), Expect = 0.079, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 27/76 (35%), Gaps = 4/76 (5%) Query: 123 VKRKNVFALPT--DMPIEDGAFIEPITVGLH--AFHLAQGCENKNVIIIGAGTIGLLAIQ 178 V P P+ + A + V A L G E K V I G G +G Sbjct: 168 VPGVFTSKPPELWGNPVREYATGFGVAVATREMAKKLWGGIEGKTVAIQGMGNVGRWTAY 227 Query: 179 CAVALGAKSVTAIDIS 194 +GAK + DI+ Sbjct: 228 WLEKMGAKVIAVSDIN 243 >5C7I-O nrPDB Length = 333 Score = 34.2 bits (77), Expect = 0.086, Method: Composition-based stats. Identities = 23/134 (17%), Positives = 41/134 (30%), Gaps = 23/134 (17%) Query: 163 NVIIIGAGTIGLLAIQCAVALGAKSVTAID--ISSEKLALAKSFGAMQT----------- 209 V I G G IG L ++ + G + V D I E + + + Sbjct: 3 TVGINGFGRIGRLVLRVCMEKGIRVVAVNDPFIDPEYMVYMFKYDSTHGRYKGNVEHKNG 62 Query: 210 --------FNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGT 261 N+ + P+ N ++E GV ++E A A+ +V Sbjct: 63 QLVVDNLEINTYQCKDPKEIPWSS--IGNPYVVECTGVYLSIEAASAHISSGARRVVVTA 120 Query: 262 LHQDLHLTSATFGK 275 D + + Sbjct: 121 PSPDAPMFVMGVNE 134 >4N7R-A nrPDB Length = 472 Score = 34.2 bits (77), Expect = 0.095, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 31/66 (46%), Gaps = 6/66 (9%) Query: 144 EPITVGLHAFHLAQGCENKN------VIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEK 197 ++V A LA ++ + +IGAG +G L I+ +A G V ++ S E+ Sbjct: 184 GAVSVSSAAVELALMKLPQSSNVSARMCVIGAGKMGKLVIKHLMAKGCTKVVVVNRSEER 243 Query: 198 LALAKS 203 ++ + Sbjct: 244 VSAIRE 249 >5ILO-A nrPDB Length = 271 Score = 33.8 bits (76), Expect = 0.10, Method: Composition-based stats. Identities = 14/39 (35%), Positives = 18/39 (46%) Query: 164 VIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAK 202 V+ GAG IGL + +A GA V ID+ K Sbjct: 19 VVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVK 57 >4FHN-X nrPDB Length = 450 Score = 33.8 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 22/106 (20%), Positives = 35/106 (33%), Gaps = 15/106 (14%) Query: 140 GAFIEPITVGLHAF--------HLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAI 191 G+ I P G G E V + G+G + AI+ A+ GA+ +TA Sbjct: 206 GSLIRPEATGYGLVYFTEAMLKRHGMGFEGMRVSVSGSGNVAQYAIEKAMEFGARVITAS 265 Query: 192 DISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETA 237 D S + F +++ R+ R E Sbjct: 266 DSSGTVVD-------ESGFTKEKLARLIEIKSSRDGRVADYAKEFG 304 >3PPI-A nrPDB Length = 281 Score = 33.8 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 28/129 (21%), Positives = 46/129 (35%), Gaps = 2/129 (1%) Query: 142 FIEPITVGLHAFHLAQGCENKNVIIIG-AGTIGLLAIQCAVALGAKSVTAIDISSEKLAL 200 +E T G + + E + I+ G AG +G ++ A G V A + + AL Sbjct: 11 TLEAQTQGPGSMVTIKQFEGASAIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKAL 70 Query: 201 AKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQ-TVELAVEIAGPHAQLALV 259 A G F S+ +++ E L A V +A I A + Sbjct: 71 ADELGNRAEFVSTNVTSEDSVLAAIEAANQLGRLRYAVVAHGGFGVAQRIVQRDGSPADM 130 Query: 260 GTLHQDLHL 268 G + + L Sbjct: 131 GGFTKTIDL 139 >2VHY-A nrPDB Length = 377 Score = 33.8 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 18/46 (39%), Positives = 27/46 (58%), Gaps = 4/46 (8%) Query: 164 VIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQT 209 V++IGAGT G A + A +GA +VT +DI+ +KL + A Sbjct: 171 VVVIGAGTAGYNAARIANGMGA-TVTVLDINIDKL---RQLDAEFC 212 >3D3W-A nrPDB Length = 244 Score = 33.8 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 31/82 (37%), Gaps = 1/82 (1%) Query: 160 ENKNVIIIGAG-TIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAP 218 + V++ GAG IG +Q A GA+ V ++ +L + ++ Sbjct: 6 AGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWE 65 Query: 219 QMQSVLRELRFNQLILETAGVP 240 + L + L++ A V Sbjct: 66 ATERALGSVGPVDLLVNNAAVA 87 >1GPJ-A nrPDB Length = 404 Score = 33.8 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 25/134 (18%), Positives = 51/134 (38%), Gaps = 14/134 (10%) Query: 115 GGFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCEN----KNVIIIGAG 170 G E + + + L E +++G A LA+ K V+++GAG Sbjct: 117 GTLDEALKIVFRRAINLGKRAREETRISEGAVSIGSAAVELAERELGSLHDKTVLVVGAG 176 Query: 171 TIGLLAIQCAVALGAKSVTAIDISSEK-LALAKSFGAMQTFNSSEMSAPQMQSVLRELRF 229 +G + V G ++V + + E+ + LA+ G A + ++ L Sbjct: 177 EMGKTVAKSLVDRGVRAVLVANRTYERAVELARDLG---------GEAVRFDELVDHLAR 227 Query: 230 NQLILETAGVPQTV 243 + +++ P V Sbjct: 228 SDVVVSATAAPHPV 241 >1JWB-B nrPDB Length = 249 Score = 33.8 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 17/33 (51%) Query: 162 KNVIIIGAGTIGLLAIQCAVALGAKSVTAIDIS 194 V+I+G G +G A Q + G ++T +D Sbjct: 32 SRVLIVGLGGLGCAASQYLASAGVGNLTLLDFD 64 >3BKW-A nrPDB Length = 243 Score = 33.8 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 22/149 (14%), Positives = 45/149 (30%), Gaps = 18/149 (12%) Query: 180 AVALGAKSVTAIDISSEKLALAKSFGAMQTFNSS--EMSAPQMQSVLRELRFNQLILETA 237 A GA V +D+S + LA A++ G ++ + +L ++ L L Sbjct: 61 AHEHGASYVLGLDLSEKMLARARAAGPDTGITYERADLDKLHLPQDSFDLAYSSLALHYV 120 Query: 238 -GVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPG 296 V + + P V + +++ A G + E WP Sbjct: 121 EDVARLFRTVHQALSPGGH--FVFSTEHPIYMAPARPGWAIDAE---------GRRTWPI 169 Query: 297 QEW----ETASRLLTERKLSLEPLIAHRG 321 + + L + + + Sbjct: 170 DRYLVEGPRKTDWLAKGVVKHHRTVGTTL 198 >5WQS-A nrPDB Length = 498 Score = 33.8 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 20/64 (31%), Gaps = 2/64 (3%) Query: 75 LHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTD 134 L GD V + C E Y + + F G + +Y+V K + Sbjct: 170 LKAGDIVDIE--VGCGAAGELRYPSYPETQGWVFPGIGEFQCYDKYMVADWKEAVKQAGN 227 Query: 135 MPIE 138 E Sbjct: 228 ADWE 231 >2YFH-A nrPDB Length = 448 Score = 33.4 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 22/106 (20%), Positives = 35/106 (33%), Gaps = 15/106 (14%) Query: 140 GAFIEPITVGLHAF--------HLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAI 191 G+ I P G G E V + G+G + AI+ A+ GA+ +TA Sbjct: 202 GSLIRPEATGYGLVYFTEAMLKRHGMGFEGMRVSVSGSGNVAQYAIEKAMEFGARVITAS 261 Query: 192 DISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETA 237 D S + F +++ R+ R E Sbjct: 262 DSSGTVVD-------ESGFTKEKLARLIEIKASRDGRVADYAKEFG 300 >5XW0-A nrPDB Length = 460 Score = 33.4 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 32/179 (17%), Positives = 56/179 (31%), Gaps = 22/179 (12%) Query: 117 FAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGL-----------HAFHLAQGCENKNVI 165 F +Y ++ + L G+ I P G HA + + + K V Sbjct: 166 FGQYRKIRNQWEGVLTGKGGSWGGSLIRPEATGYGVVYYVEHMIAHATNGQESFKGKRVA 225 Query: 166 IIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLR 225 I G+G + A + LG V+ D N P+ ++ Sbjct: 226 ISGSGNVAQYAALKVIELGGSVVSLSDSQGS-----------LIINGEGSFTPEEIELIA 274 Query: 226 ELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVI 284 + + + L + A + V D+ L SAT +I +E V+ Sbjct: 275 QTKVERKQLASIVGAAPFSDANKFKYIAGARPWVHVGKVDVALPSATQNEISGEEAQVL 333 >1PS9-A nrPDB Length = 671 Score = 33.4 bits (75), Expect = 0.16, Method: Composition-based stats. Identities = 28/143 (19%), Positives = 49/143 (34%), Gaps = 20/143 (13%) Query: 141 AFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSE---K 197 + P + + KN+ ++GAG GL A A G VT D SE + Sbjct: 353 CLVNPRACHETKMPILPAVQKKNLAVVGAGPAGLAFAINAAARG-HQVTLFDAHSEIGGQ 411 Query: 198 LALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVE---LAVEIAGPHA 254 +AK P + LR+ + ++E GV + A ++ Sbjct: 412 FNIAKQI-------------PGKEEFYETLRYYRRMIEVTGVTLKLNHTVTADQLQAFDE 458 Query: 255 QLALVGTLHQDLHLTSATFGKIL 277 + G + + + K+L Sbjct: 459 TILASGIVPRTPPIDGIDHPKVL 481 >2GPY-A nrPDB Length = 233 Score = 33.1 bits (74), Expect = 0.18, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 38/111 (34%), Gaps = 8/111 (7%) Query: 153 FHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALA----KSFGAMQ 208 HL + ++ IG IG AI+ A AL ++ +I+ + A K+ G Sbjct: 47 LHLLKMAAPARILEIGT-AIGYSAIRMAQALPEATIVSIERDERRYEEAHKHVKALGLES 105 Query: 209 TFNSSEMSAPQMQSVLRELRFNQLILETAGVPQT---VELAVEIAGPHAQL 256 A Q+ L ++ A Q ++ + P + Sbjct: 106 RIELLFGDALQLGEKLELYPLFDVLFIDAAKGQYRRFFDMYSPMVRPGGLI 156 >1A5Z-A nrPDB Length = 319 Score = 33.1 bits (74), Expect = 0.20, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 41/99 (41%), Gaps = 8/99 (8%) Query: 163 NVIIIGAGTIGLLAIQCAVALG-AKSVTAIDISSEKLALAKSFGAMQTF--NSSEMSAPQ 219 + I+G G +G + G A+ + ID+ ++ A+ A Sbjct: 2 KIGIVGLGRVGSSTAFALLMKGFAREMVLIDVDKKRAE----GDALDLIHGTPFTRRANI 57 Query: 220 MQSVLRELRFNQLILETAGVPQ-TVELAVEIAGPHAQLA 257 +L+ + +++ AGVPQ E +++ G +A++ Sbjct: 58 YAGDYADLKGSDVVIVAAGVPQKPGETRLQLLGRNARVM 96 >5Z1Z-A nrPDB Length = 329 Score = 33.1 bits (74), Expect = 0.21, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 17/49 (34%), Gaps = 3/49 (6%) Query: 161 NKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQT 209 K +IG G IG+ ++ G + A D A A G Sbjct: 144 GKTAGVIGTGKIGVAMLRILKGFGM-RLLAFDPYPS--AAALELGVEYV 189 >3V2G-A nrPDB Length = 271 Score = 32.7 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 29/161 (18%), Positives = 56/161 (34%), Gaps = 12/161 (7%) Query: 160 ENKNVIIIGAG-TIGLLAIQCAVALGAKSVTAIDISSEKLALA------KSFGAMQTFNS 212 K + G IG + GA V +++ + A A ++ G + Sbjct: 30 AGKTAFVTGGSRGIGAAIAKRLALEGAA-VALTYVNAAERAQAVVSEIEQAGGRAVAIRA 88 Query: 213 SEMSAPQMQSVLRE----LRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHL 268 A ++ +RE L +++ +AG+ + L ++ V + + Sbjct: 89 DNRDAEAIEQAIRETVEALGGLDILVNSAGIWHSAPLEETTVADFDEVMAVNFRAPFVAI 148 Query: 269 TSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTER 309 SA+ + IGS + PWPG +AS+ Sbjct: 149 RSASRHLGDGGRIITIGSNLAELVPWPGISLYSASKAALAG 189 >1DXY-A nrPDB Length = 333 Score = 32.7 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 16/50 (32%), Positives = 21/50 (42%), Gaps = 6/50 (12%) Query: 153 FHLAQGCENK-----NVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEK 197 + A K V ++G G IG +AI+ GAK V A D K Sbjct: 132 YEKAGTFIGKELGQQTVGVMGTGHIGQVAIKLFKGFGAK-VIAYDPYPMK 180 >2HMT-A nrPDB Length = 144 Score = 32.7 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 28/70 (40%), Gaps = 1/70 (1%) Query: 165 IIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVL 224 +IG G G ++ +G V A+DI+ EK+ S+ ++ + + Sbjct: 10 AVIGLGRFGGSIVKELHRMG-HEVLAVDINEEKVNAYASYATHAVIANATEENELLSLGI 68 Query: 225 RELRFNQLIL 234 R + + + Sbjct: 69 RNFEYVIVAI 78 >5BUT-A nrPDB Length = 288 Score = 32.7 bits (73), Expect = 0.25, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 28/70 (40%), Gaps = 1/70 (1%) Query: 165 IIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVL 224 +IG G G ++ +G V A+DI+ EK+ S+ ++ + + Sbjct: 10 AVIGLGRFGGSIVKELHRMG-HEVLAVDINEEKVNAYASYATHAVIANATEENELLSLGI 68 Query: 225 RELRFNQLIL 234 R + + + Sbjct: 69 RNFEYVIVAI 78 Score = 32.7 bits (73), Expect = 0.25, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 28/70 (40%), Gaps = 1/70 (1%) Query: 165 IIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVL 224 +IG G G ++ +G V A+DI+ EK+ S+ ++ + + Sbjct: 152 AVIGLGRFGGSIVKELHRMG-HEVLAVDINEEKVNAYASYATHAVIANATEENELLSLGI 210 Query: 225 RELRFNQLIL 234 R + + + Sbjct: 211 RNFEYVIVAI 220 >4X28-D nrPDB Length = 373 Score = 32.7 bits (73), Expect = 0.25, Method: Composition-based stats. Identities = 33/204 (16%), Positives = 52/204 (25%), Gaps = 43/204 (21%) Query: 69 GSGVDDLHPGDA---VACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKR 125 G GV + GD VA + G Y G+R G+ Sbjct: 109 GWGVSAVS-GDRILTVALDGEMGEGPVQAAGTGH-----GYRLTGTRTQVGYG-----PV 157 Query: 126 KNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNV---IIIGAGTIGLLAIQCAVA 182 + F +P + F+ +A G V G G++G L + A Sbjct: 158 ADAFLVPAETDSGAAVFL-----------VAAGDPGVAVTALATTGLGSVGHLELNGAKV 206 Query: 183 LGAKSVTAIDI---------------SSEKLALAKSFGAMQTFNSSEMSAPQMQSVLREL 227 A+ V D+ L A + P Sbjct: 207 DAARRVGGTDVAVWLGTLSTLSRTAFQLGVLERGLQMTAEYARTREQFDRPIGSFQAVGQ 266 Query: 228 RFNQLILETAGVPQTVELAVEIAG 251 R ++ G+ T+ A Sbjct: 267 RLADGYIDVKGLRLTLTQAAWRVA 290 >4CUK-A nrPDB Length = 338 Score = 32.7 bits (73), Expect = 0.26, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 17/49 (34%), Gaps = 3/49 (6%) Query: 161 NKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQT 209 K +IG G IG+ A++ G + A D A G Sbjct: 144 GKTAGVIGTGKIGVAALRILKGFGM-RLLAFDPYPS--TAALDLGVEYV 189 >1QO8-A nrPDB Length = 566 Score = 32.3 bits (72), Expect = 0.30, Method: Composition-based stats. Identities = 13/46 (28%), Positives = 21/46 (45%), Gaps = 1/46 (2%) Query: 150 LHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISS 195 + A E V+++GAG+ G A A GA +V +D + Sbjct: 110 IQKAIAAGPSETTQVLVVGAGSAGFNASLAAKKAGA-NVILVDKAP 154 >2VYN-D nrPDB Length = 334 Score = 32.3 bits (72), Expect = 0.35, Method: Composition-based stats. Identities = 23/134 (17%), Positives = 40/134 (29%), Gaps = 23/134 (17%) Query: 163 NVIIIGAGTIGLLAIQCAVALGAKSVTAID--ISSEKLALAKSFGAMQT----------- 209 V I G G IG L ++ + G + V D I E + + + Sbjct: 3 KVGINGFGRIGRLVLRVCMEKGVRVVAVNDPFIDPEYMVYMFKYDSTHGRYKGTVEHKNG 62 Query: 210 --------FNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGT 261 N + P+ N ++E GV ++E A A+ +V Sbjct: 63 RLVVDNLEINVFQCKEPKEIPWSS--VGNPYVVEATGVYLSIEAASGHISSGARRVIVTA 120 Query: 262 LHQDLHLTSATFGK 275 D + + Sbjct: 121 PSPDAPMLVMGVNE 134 >2O23-A nrPDB Length = 265 Score = 32.3 bits (72), Expect = 0.35, Method: Composition-based stats. Identities = 21/84 (25%), Positives = 32/84 (38%), Gaps = 5/84 (5%) Query: 164 VIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSE---MSAPQM 220 VI GA +GL + V GA +V +S A AK G F ++ Q Sbjct: 16 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQT 75 Query: 221 QSVLRELRFN--QLILETAGVPQT 242 L + +F + + AG+ Sbjct: 76 ALALAKGKFGRVDVAVNCAGIAVA 99 >2A9F-A nrPDB Length = 398 Score = 32.3 bits (72), Expect = 0.35, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 30/65 (46%), Gaps = 1/65 (1%) Query: 129 FALPTDMPIEDGAFIEPITVGLHAFHLAQGCENK-NVIIIGAGTIGLLAIQCAVALGAKS 187 +P + G I + ++ L + ++ ++++ G G+ GL + +A GA Sbjct: 155 CHIPVFHDDQHGTAIVVLAAIFNSLKLLKKSLDEVSIVVNGGGSAGLSITRKLLAAGATK 214 Query: 188 VTAID 192 VT +D Sbjct: 215 VTVVD 219 >2EEZ-A nrPDB Length = 369 Score = 31.9 bits (71), Expect = 0.37, Method: Composition-based stats. Identities = 14/37 (37%), Positives = 26/37 (70%), Gaps = 1/37 (2%) Query: 163 NVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLA 199 +V+I+G GT+G A + A+ +GA VT +D++ ++L Sbjct: 168 SVVILGGGTVGTNAAKIALGMGA-QVTILDVNHKRLQ 203 >1ZFN-A nrPDB Length = 253 Score = 31.9 bits (71), Expect = 0.37, Method: Composition-based stats. Identities = 11/44 (25%), Positives = 16/44 (36%) Query: 152 AFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISS 195 A Q + V+IIG G +G A G ++ D Sbjct: 21 ALDGQQKLLDSQVLIIGLGGLGTPAALYLAGAGVGTLVLADDDD 64 >1CRW-G nrPDB Length = 333 Score = 31.9 bits (71), Expect = 0.37, Method: Composition-based stats. Identities = 24/135 (17%), Positives = 42/135 (31%), Gaps = 23/135 (17%) Query: 162 KNVIIIGAGTIGLLAIQCAVALGAKSVTAIDI-----------------SSEKLALAKSF 204 + I G G IG L ++ A+ +GA+ V D K + Sbjct: 1 SKIGINGFGRIGRLVLRAALEMGAQVVAVNDPFIALEYMVYMFKYDSTHGMFKGEVKAED 60 Query: 205 GAMQT----FNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALVG 260 GA+ P+ + + I+E+ GV T+E A A+ ++ Sbjct: 61 GALVVDGKKITVFNEMKPENIPWSK--AGAEYIVESTGVFTTIEKASAHFKGGAKKVIIS 118 Query: 261 TLHQDLHLTSATFGK 275 D + Sbjct: 119 APSADAPMFVCGVNL 133 >1E3W-A nrPDB Length = 261 Score = 31.9 bits (71), Expect = 0.38, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 33/87 (37%), Gaps = 5/87 (5%) Query: 164 VIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSV 223 VI GA +GL + V GA +V +SE AK G F + +++ + Sbjct: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQA 73 Query: 224 L-----RELRFNQLILETAGVPQTVEL 245 + + + AG+ ++ Sbjct: 74 ALTLAKEKFGRIDVAVNCAGIAVAIKT 100 >6CU3-A nrPDB Length = 336 Score = 31.9 bits (71), Expect = 0.40, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 32/77 (41%), Gaps = 7/77 (9%) Query: 162 KNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSF----GAMQTFNSSEMSA 217 K V+ IG GT G+L + A A GAK V ID+S + A+ G + Sbjct: 53 KVVLDIGCGT-GILCLFAAKA-GAKRVIGIDMSDI-IDKARQIVSDNGYSHVIELIKGKV 109 Query: 218 PQMQSVLRELRFNQLIL 234 + + + +I+ Sbjct: 110 EDIAQLPFGIEKVDIII 126 >5JXW-A nrPDB Length = 498 Score = 31.9 bits (71), Expect = 0.40, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 25/77 (32%), Gaps = 3/77 (3%) Query: 157 QGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMS 216 Q K ++++G G +G Q +GA V +I A G + E Sbjct: 267 QMLAGKKIVVLGYGEVGKGCAQGLSGVGA-RVIVTEIDPICALQASMEG--YQVSVLEDV 323 Query: 217 APQMQSVLRELRFNQLI 233 + + +I Sbjct: 324 VSEADIFITATGNKDVI 340 >1JG3-A nrPDB Length = 235 Score = 31.9 bits (71), Expect = 0.41, Method: Composition-based stats. Identities = 32/158 (20%), Positives = 58/158 (36%), Gaps = 21/158 (13%) Query: 117 FAEYIVVKRKN--VFALPTDMPIEDGAFI-EPITVGLHAFHLAQGCENKNVIIIGAGTIG 173 + Y+ V+ K + +PI G + P V + +A N++ +G G+ G Sbjct: 46 YPRYLSVEDKYKKYAHIDEPLPIPAGQTVSAPHMVAIM-LEIANLKPGMNILEVGTGS-G 103 Query: 174 LLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFN--- 230 A + + V I+ E + AK N + +L + Sbjct: 104 WNAALISEIV-KTDVYTIERIPELVEFAKR-------NLERAGVKNVHVILGDGSKGFPP 155 Query: 231 ----QLILETAGVPQTVELAVEIAGPHAQLAL-VGTLH 263 +I+ TAG P+ E +E +L + VG+ H Sbjct: 156 KAPYDVIIVTAGAPKIPEPLIEQLKIGGKLIIPVGSYH 193 >3EGI-A nrPDB Length = 206 Score = 31.9 bits (71), Expect = 0.41, Method: Composition-based stats. Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 2/40 (5%) Query: 164 VIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKS 203 V++ +G IQ A L V AIDI K+ALA++ Sbjct: 46 VVVDAFCGVGGNTIQFA--LTGMRVIAIDIDPVKIALARN 83 >3GDH-A nrPDB Length = 241 Score = 31.9 bits (71), Expect = 0.41, Method: Composition-based stats. Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 2/40 (5%) Query: 164 VIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKS 203 V++ +G IQ A L V AIDI K+ALA++ Sbjct: 81 VVVDAFCGVGGNTIQFA--LTGMRVIAIDIDPVKIALARN 118 >6C55-A nrPDB Length = 340 Score = 31.9 bits (71), Expect = 0.42, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 23/80 (28%), Gaps = 1/80 (1%) Query: 145 PITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSF 204 TV + K + ++G G+ G Q G V I AK Sbjct: 1 MTTVYYDQDVKTDALQGKKIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGRS-FDKAKED 59 Query: 205 GAMQTFNSSEMSAPQMQSVL 224 G + + + VL Sbjct: 60 GFDVFPVAEAVKQADVIMVL 79 >4PZE-A nrPDB Length = 284 Score = 31.5 bits (70), Expect = 0.49, Method: Composition-based stats. Identities = 28/161 (17%), Positives = 55/161 (34%), Gaps = 19/161 (11%) Query: 162 KNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGA---MQTFNSSEMSAP 218 + V I+GAGT+G Q +G +V +DIS + + A + +++ Sbjct: 4 RTVGIVGAGTMGNGIAQACAVVGL-NVVMVDISDAAVQKGVATVASSLDRLIKKEKLTEA 62 Query: 219 QMQSVLRELRFN---------QLILETAGVPQTVELAVEIAGPHAQLA--LVGTLHQDLH 267 S L ++ + +++E A + +L V+I + V Sbjct: 63 DKASALARIKGSTSYDDLKATDIVIEAA--TENYDLKVKILKQIDGIVGENVIIASNTSS 120 Query: 268 LTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTE 308 ++ + + IG +P P R L Sbjct: 121 ISITKLAAVTSRADRFIGMHFF--NPVPVMALVELIRGLQT 159 >2ZZN-A nrPDB Length = 336 Score = 31.5 bits (70), Expect = 0.51, Method: Composition-based stats. Identities = 26/118 (22%), Positives = 47/118 (39%), Gaps = 10/118 (8%) Query: 144 EPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKS 203 P G A + + N V+ + AG +G +I C AK + AIDI+ + L K Sbjct: 179 SPRLGGERARIMKKVSLNDVVVDMFAG-VGPFSIAC---KNAKKIYAIDINPHAIELLKK 234 Query: 204 FGAMQTFNSSEMSAPQMQSVLR--ELRFNQLILETAGVPQTV-ELAVEIAGPHAQLAL 258 N E + S +R +++ N++I+ + A++I + Sbjct: 235 ---NIKLNKLEHKIIPILSDVREVDVKGNRVIMNLPKFAHKFIDKALDIVEEGGVIHY 289 >5JJC-A nrPDB Length = 342 Score = 31.5 bits (70), Expect = 0.54, Method: Composition-based stats. Identities = 14/60 (23%), Positives = 20/60 (33%), Gaps = 2/60 (3%) Query: 152 AFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAI--DISSEKLALAKSFGAMQT 209 A ++ AG G+ A ALG ++ I S EK + GA Sbjct: 53 AEKRGLLRPGGVIVEGTAGNTGIGLTMVAKALGYRTAIVIPETASQEKKDALRLLGAELI 112 >4J90-A nrPDB Length = 222 Score = 31.5 bits (70), Expect = 0.55, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 27/70 (38%), Gaps = 1/70 (1%) Query: 165 IIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVL 224 +IG G G + +G V A+DI+ EK+ S+ ++ + + Sbjct: 10 AVIGLGRFGGSICKELHRMG-HEVLAVDINEEKVNAYASYATHAVIANATEENELLSLGI 68 Query: 225 RELRFNQLIL 234 R + + + Sbjct: 69 RNFEYVIVAI 78 >3HM2-A nrPDB Length = 178 Score = 31.5 bits (70), Expect = 0.58, Method: Composition-based stats. Identities = 18/123 (14%), Positives = 35/123 (28%), Gaps = 10/123 (8%) Query: 152 AFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLAL----AKSFGAM 207 A ++ + IG G G +AI+ + + +IS E+ A + G Sbjct: 17 AISALAPKPHETLWDIG-GGSGSIAIEWLRSTPQTTAVCFEISEERRERILSNAINLGVS 75 Query: 208 QTFNSSEMSAPQMQSVLRELRFNQLILETAG--VPQTVELAVEIAGPHAQLALVGTLHQD 265 + + V +I G P A + +L + Sbjct: 76 DRIAVQQGAPRAFDDVPDN---PDVIFIGGGLTAPGVFAAAWKRLPVGGRLVANAVTVES 132 Query: 266 LHL 268 + Sbjct: 133 EQM 135 >5ZBK-A nrPDB Length = 203 Score = 31.5 bits (70), Expect = 0.59, Method: Composition-based stats. Identities = 25/166 (15%), Positives = 44/166 (26%), Gaps = 15/166 (9%) Query: 141 AFIEPITVGLHAFHLAQGCENKNVI------IIGAGTIGLLAIQCAVALGAKSVTAIDIS 194 F + A +++ + G G +GL+ A A A I I Sbjct: 8 VFCGASPGASPVYQEAAVALGRHLAERGLTLVYGGGAVGLMGT-VADAALAAGGEVIGII 66 Query: 195 SEKLALAK-------SFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAV 247 + L A+ + ++ + ++ L LE T Sbjct: 67 PQSLQEAEIGHKGLTRLEVVDGMHARKARMAELADAFIALPGGLGTLEALFEVWTWGQLG 126 Query: 248 EIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSP 293 A P L + G L + + G +SP Sbjct: 127 YHAKPLGLLEVNGFYDPLLTFLDHLVDERFVRA-EHRGMLQRGASP 171 >3HDH-A nrPDB Length = 302 Score = 31.5 bits (70), Expect = 0.60, Method: Composition-based stats. Identities = 23/101 (22%), Positives = 40/101 (39%), Gaps = 10/101 (9%) Query: 157 QGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMS 216 + K+V +IG G +G Q A A G +V +D + + LA +K G ++ Sbjct: 11 KKILVKHVTVIGGGLMGAGIAQVAAATG-HTVVLVDQTEDILAKSKK-GIEESL-RKVAK 67 Query: 217 APQMQSVLRELRFNQLIL-------ETAGVPQTVELAVEIA 250 ++ F + L + A V + +L VE Sbjct: 68 KKFAENPKAGDEFVEKTLSSISTSTDAASVVHSTDLVVEAI 108 >4K2X-A nrPDB Length = 523 Score = 31.5 bits (70), Expect = 0.61, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 23/42 (54%), Gaps = 1/42 (2%) Query: 164 VIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFG 205 V+I GAG GL+ GA+++ ++ +E + +K+ G Sbjct: 25 VVIAGAGPTGLMLACELRLAGARTL-VLERLAEPVDFSKALG 65 >6J0Z-C nrPDB Length = 491 Score = 31.1 bits (69), Expect = 0.63, Method: Composition-based stats. Identities = 20/121 (16%), Positives = 41/121 (33%), Gaps = 8/121 (6%) Query: 162 KNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQ 221 +V+++GAG GL+ G V +D +E + +++ G S + + Sbjct: 6 SDVVVVGAGPTGLMLAGELRLAGVS-VVVLDKLAEPIKESRALG------FSARTIEEFA 58 Query: 222 SVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKEL 281 RF ++ + G V L ++ G + + L E+ Sbjct: 59 QRGLMDRFGEVGVIPVGHFGGVPLDYQVIE-GGSYGARGIPQARTEGILGGWARELGAEV 117 Query: 282 T 282 Sbjct: 118 R 118 >3VH2-A nrPDB Length = 616 Score = 31.1 bits (69), Expect = 0.63, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 40/92 (43%), Gaps = 15/92 (16%) Query: 158 GCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAID------ISSEKLALAKSFGAMQTFN 211 +N V+++GAGT+G + +A G + +T +D + + AL +N Sbjct: 324 IIKNTKVLLLGAGTLGCYVSRALIAWGVRKITFVDNGTVSYSNPVRQAL---------YN 374 Query: 212 SSEMSAPQMQSVLRELRFNQLILETAGVPQTV 243 + P+ + L+ +++ GV ++ Sbjct: 375 FEDCGKPKAELAAASLKRIFPLMDATGVKLSI 406 >3T7E-A nrPDB Length = 344 Score = 31.1 bits (69), Expect = 0.63, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 40/92 (43%), Gaps = 15/92 (16%) Query: 158 GCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAID------ISSEKLALAKSFGAMQTFN 211 +N V+++GAGT+G + +A G + +T +D + + AL +N Sbjct: 35 IIKNTKVLLLGAGTLGCYVSRALIAWGVRKITFVDNGTVSYSNPVRQAL---------YN 85 Query: 212 SSEMSAPQMQSVLRELRFNQLILETAGVPQTV 243 + P+ + L+ +++ GV ++ Sbjct: 86 FEDCGKPKAELAAASLKRIFPLMDATGVKLSI 117 >3OND-A nrPDB Length = 488 Score = 31.1 bits (69), Expect = 0.63, Method: Composition-based stats. Identities = 17/137 (12%), Positives = 38/137 (27%), Gaps = 13/137 (9%) Query: 160 ENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFG------------AM 207 K ++ G G +G GA V +I A G A Sbjct: 264 AGKVAVVAGYGDVGKGCAAALKQAGA-RVIVTEIDPICALQATMEGLQVLTLEDVVSEAD 322 Query: 208 QTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLH 267 ++ M +++++ N ++ +++ P + + Sbjct: 323 IFVTTTGNKDIIMLDHMKKMKNNAIVCNIGHFDNEIDMLGLETHPGVKRITIKPQTDRWV 382 Query: 268 LTSATFGKILRKELTVI 284 G I+ E ++ Sbjct: 383 FPETNTGIIILAEGRLM 399 >3G1U-A nrPDB Length = 437 Score = 31.1 bits (69), Expect = 0.64, Method: Composition-based stats. Identities = 8/36 (22%), Positives = 12/36 (33%), Gaps = 1/36 (2%) Query: 160 ENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISS 195 K + G G +G A GA V ++ Sbjct: 211 AGKTCCVCGYGDVGKGCAAALRAFGA-RVVVTEVDP 245 >6NJP-A nrPDB Length = 449 Score = 31.1 bits (69), Expect = 0.67, Method: Composition-based stats. Identities = 34/226 (15%), Positives = 73/226 (32%), Gaps = 20/226 (8%) Query: 125 RKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGC-ENKNVIIIGAGTIGLLAIQCAVAL 183 ++++A P D P+ +P +G+ A C + + I +G + + Sbjct: 137 ERSLYAEPPD-PLLRQVIDQPFILGVRAIDGLLTCGIGQRIGIFAGSGVGKSTLLGMICN 195 Query: 184 GA-KSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQT 242 GA + + + E+ F A S +S + + LE T Sbjct: 196 GASADIIVLALIGERGREVNEFLA--LLPQSTLSKCVLVVTTSDRP----ALERMKAAFT 249 Query: 243 VELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETA 302 E + L+ + +A + E V G + P + + Sbjct: 250 ATTIAEYFRDQGKNVLLMMDSVTRYARAARDVGLASGEPDVRGGF-------PPSVFSSL 302 Query: 303 SRLLTERKLSLEPLIAHRGSF----ESFAQAVRDIARNAMPGKVLL 344 +LL + + I + ++ + D R+ + G ++L Sbjct: 303 PKLLERAGPAPKGSITAIYTVLLESDNVNDPIGDEVRSILDGHIVL 348 >3KYD-B nrPDB Length = 551 Score = 31.1 bits (69), Expect = 0.68, Method: Composition-based stats. Identities = 12/41 (29%), Positives = 20/41 (48%) Query: 154 HLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDIS 194 LA+ V+++GAG IG ++ V G + ID+ Sbjct: 12 ELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLD 52 >2EKL-A nrPDB Length = 313 Score = 31.1 bits (69), Expect = 0.70, Method: Composition-based stats. Identities = 22/100 (22%), Positives = 33/100 (33%), Gaps = 17/100 (17%) Query: 160 ENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQT---------- 209 K + I+G G IG A A+G K V A DI + A+ A Sbjct: 141 AGKTIGIVGFGRIGTKVGIIANAMGMK-VLAYDILDIR-EKAEKINAKAVSLEELLKNSD 198 Query: 210 -----FNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVE 244 S+ + P + EL + +I+ V Sbjct: 199 VISLHVTVSKDAKPIIDYPQFELMKDNVIIVNTSRAVAVN 238 >3KYC-B nrPDB Length = 660 Score = 31.1 bits (69), Expect = 0.70, Method: Composition-based stats. Identities = 12/41 (29%), Positives = 20/41 (48%) Query: 154 HLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDIS 194 LA+ V+++GAG IG ++ V G + ID+ Sbjct: 30 ELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLD 70 >1DL5-A nrPDB Length = 317 Score = 31.1 bits (69), Expect = 0.72, Method: Composition-based stats. Identities = 19/114 (16%), Positives = 37/114 (32%), Gaps = 16/114 (14%) Query: 153 FHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAK-SVTAIDISSEKLALAKSFGAMQTFN 211 + V+ IG G G A + +G K V +++ S + +AK N Sbjct: 68 MEWVGLDKGMRVLEIG-GGTGYNAAVMSRVVGEKGLVVSVEYSRKICEIAKR-------N 119 Query: 212 SSEMSAPQMQSVLRELRFN-------QLILETAGVPQTVELAVEIAGPHAQLAL 258 + + V + + +I T GV + E ++ + Sbjct: 120 VERLGIENVIFVCGDGYYGVPEFSPYDVIFVTVGVDEVPETWFTQLKEGGRVIV 173 >1VH3-A nrPDB Length = 262 Score = 31.1 bits (69), Expect = 0.76, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 20/54 (37%), Gaps = 2/54 (3%) Query: 180 AVALGAKSVTAIDISSEKLALAKSFGAMQTFNS--SEMSAPQMQSVLRELRFNQ 231 A+ GA V + +AKSFGA S ++ V+ +L Sbjct: 37 ALQSGASRVIIATDNENVADVAKSFGAEVCMTSVNHNSGTERLAEVVEKLAIPD 90 >3FBT-A nrPDB Length = 282 Score = 30.7 bits (68), Expect = 0.82, Method: Composition-based stats. Identities = 7/34 (20%), Positives = 15/34 (44%) Query: 164 VIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEK 197 +++G+G +Q AK + + + EK Sbjct: 125 CVVLGSGGAARAVLQYLKDNFAKDIYVVTRNPEK 158 >2OBL-A nrPDB Length = 347 Score = 30.7 bits (68), Expect = 0.89, Method: Composition-based stats. Identities = 34/226 (15%), Positives = 73/226 (32%), Gaps = 20/226 (8%) Query: 125 RKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGC-ENKNVIIIGAGTIGLLAIQCAVAL 183 ++++A P D P+ +P +G+ A C + + I +G + + Sbjct: 35 ERSLYAEPPD-PLLRQVIDQPFILGVRAIDGLLTCGIGQRIGIFAGSGVGKSTLLGMICN 93 Query: 184 GA-KSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQT 242 GA + + + E+ F A S +S + + LE T Sbjct: 94 GASADIIVLALIGERGREVNEFLA--LLPQSTLSKCVLVVTTSDRP----ALERMKAAFT 147 Query: 243 VELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETA 302 E + L+ + +A + E V G + P + + Sbjct: 148 ATTIAEYFRDQGKNVLLMMDSVTRYARAARDVGLASGEPDVRGGF-------PPSVFSSL 200 Query: 303 SRLLTERKLSLEPLIAHRGSF----ESFAQAVRDIARNAMPGKVLL 344 +LL + + I + ++ + D R+ + G ++L Sbjct: 201 PKLLERAGPAPKGSITAIYTVLLESDNVNDPIGDEVRSILDGHIVL 246 >6BQ5-A nrPDB Length = 331 Score = 30.7 bits (68), Expect = 0.92, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 26/67 (38%), Gaps = 4/67 (5%) Query: 162 KNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQ 221 KNV I+G G G A + V DI E + KS+ N +++ Sbjct: 103 KNVFIMG-GGEGSTARELLRHKTIDKVVMCDIDEEVVEFCKSY---LVVNKEAFHDSRLE 158 Query: 222 SVLRELR 228 V+ + + Sbjct: 159 VVINDAK 165 >5VMT-A nrPDB Length = 342 Score = 30.7 bits (68), Expect = 0.95, Method: Composition-based stats. Identities = 20/128 (15%), Positives = 32/128 (25%), Gaps = 19/128 (14%) Query: 163 NVIIIGAGTIGLLAI-QCAVALGAKSVTAIDISSE--------------KLALAKSFGAM 207 V I G G IG LA+ Q A G + D++ + Sbjct: 12 KVAINGFGRIGRLALRQIEKAHGIEVAAVNDLTPAEMLLHLFKYDSTQGRFQGTAELKDD 71 Query: 208 QTFNSSEMSAPQMQSVLRELR----FNQLILETAGVPQTVELAVEIAGPHAQLALVGTLH 263 + EL ++LE G A A+ ++ Sbjct: 72 AIVVNGREIKVFANPNPEELPWGELGVDVVLECTGFFTNKTKAEAHIRAGARKVVISAPG 131 Query: 264 QDLHLTSA 271 + T Sbjct: 132 GNDVKTVV 139 >6GBN-A nrPDB Length = 438 Score = 30.7 bits (68), Expect = 0.97, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 27/78 (34%), Gaps = 6/78 (7%) Query: 158 GCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEM-S 216 K ++ G G +G + GA V +I A AM + +M Sbjct: 216 MMAGKVAVVAGYGDVGKGSAASLRGAGA-RVIVTEIDPICALQA----AMDGYEVKKMAD 270 Query: 217 APQMQSVLRELRFNQLIL 234 A + ++ N+ I+ Sbjct: 271 AVKRADIVVTATGNKNII 288 >1F14-A nrPDB Length = 310 Score = 30.7 bits (68), Expect = 0.97, Method: Composition-based stats. Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 1/42 (2%) Query: 162 KNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKS 203 K+V +IG G +G Q A A G +V +D + + LA +K Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATG-HTVVLVDQTEDILAKSKK 56 >4LRT-B nrPDB Length = 323 Score = 30.7 bits (68), Expect = 0.99, Method: Composition-based stats. Identities = 42/199 (21%), Positives = 64/199 (32%), Gaps = 23/199 (11%) Query: 161 NKNVI-IIGAGTIG---LLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMS 216 K V I+G G IG L+ +Q + + + + +D +SE LA A+ G E S Sbjct: 22 GKAVAAIVGPGNIGTDLLIKLQRSEHIEVRYMVGVDPASEGLARARKLGV-------EAS 74 Query: 217 APQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQL-----ALVGTLHQDL----- 266 A + +L + L+ E + A A A VG L Sbjct: 75 AEGVDWLLEQDELPDLVFEATSAKAHLANAPRYAEAGITAIDLTPAAVGPLVCPPVNLTE 134 Query: 267 HLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESF 326 HL + I I S P + + R A+ F Sbjct: 135 HLDAPNVNMITCGGQATIPIVHAVSRVVPVA-YAEIVAAIASRSAGP-GTRANIDEFTET 192 Query: 327 AQAVRDIARNAMPGKVLLI 345 A + A GK ++I Sbjct: 193 TAAAIEQVGGAARGKAIII 211 >2LDB-A nrPDB Length = 317 Score = 30.7 bits (68), Expect = 1.00, Method: Composition-based stats. Identities = 21/86 (24%), Positives = 36/86 (41%), Gaps = 10/86 (11%) Query: 161 NKNVIIIGAGTIGLLAIQCAVALG-AKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQ 219 V++IGAG +G + + G A + ID + K+ G FN ++ AP+ Sbjct: 6 GARVVVIGAGFVGASYVFALMNQGIADEIVLIDANES-----KAIGDAMDFNHGKVFAPK 60 Query: 220 MQSV----LRELRFNQLILETAGVPQ 241 + + R L++ AG Q Sbjct: 61 PVDIWHGDYDDCRDADLVVICAGANQ 86 >5AOV-A nrPDB Length = 336 Score = 30.7 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 16/48 (33%), Gaps = 2/48 (4%) Query: 161 NKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQ 208 K + I+G G IG + A + + K K GA Sbjct: 150 GKTIGIVGFGRIGQAIARRAKGFNMR--ILYYSRTRKSQAEKELGAEY 195 >3GG2-A nrPDB Length = 450 Score = 30.7 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 24/135 (17%), Positives = 43/135 (31%), Gaps = 18/135 (13%) Query: 164 VIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSV 223 + ++G G +GL++ C LGA +V ID K+ S G + + Sbjct: 5 IAVVGIGYVGLVSATCFAELGA-NVRCIDTDRNKIEQLNS-GTIPIYEPGLEKMIARNVK 62 Query: 224 LRELRFN----------QLILETAGVPQT------VELAVEIAGPHAQLALVGTLHQDLH 267 LRF +I G P + ++ A + L Sbjct: 63 AGRLRFGTEIEQAVPEADIIFIAVGTPAGEDGSADMSYVLDAARSIGRAMSRYILIVTKS 122 Query: 268 LTSATFGKILRKELT 282 +++RK + Sbjct: 123 TVPVGSYRLIRKAIQ 137 >3X43-A nrPDB Length = 332 Score = 30.4 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 26/68 (38%), Gaps = 2/68 (2%) Query: 145 PITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAID--ISSEKLALAK 202 ++V L A ++ +G +G+ A A G + V + S E+ L + Sbjct: 47 ALSVVLDAEAKGLLKPGDTIVECTSGNVGIALAMVAAARGYRFVAVMGDTYSVERRKLIR 106 Query: 203 SFGAMQTF 210 ++G Sbjct: 107 AYGGKLVL 114 >6ARH-A nrPDB Length = 338 Score = 30.4 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 27/71 (38%), Gaps = 2/71 (2%) Query: 278 RKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHR--GSFESFAQAVRDIAR 335 K + V G+ S + + A +T+ K L+ +I H S + + + A Sbjct: 61 VKNIFVNGTTGEGLSLSVSERRQVAEEWVTKGKDKLDQVIIHVGALSLKESQELAQHAAE 120 Query: 336 NAMPGKVLLIP 346 G ++ P Sbjct: 121 IGADGIAVIAP 131 >3AOE-A nrPDB Length = 424 Score = 30.4 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 14/47 (29%), Positives = 18/47 (38%) Query: 146 ITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAID 192 IT A + E V I G G +G A + GA+ V D Sbjct: 204 ITAAAAAEKIGLQVEGARVAIQGFGNVGNAAARAFHDHGARVVAVQD 250 >3H9E-O nrPDB Length = 346 Score = 30.4 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 23/132 (17%), Positives = 46/132 (34%), Gaps = 19/132 (14%) Query: 163 NVIIIGAGTIGLLAIQCAVALGAKSVTAID--ISSEKLALAKSFGAMQ------------ 208 V I G G IG L ++ + G K V D I E + + + Sbjct: 9 TVGINGFGRIGRLVLRACMEKGVKVVAVNDPFIDPEYMVYMFKYDSTHGRYKGSVEFRNG 68 Query: 209 --TFNSSEMSAPQMQSVLR---ELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLH 263 ++ E+S Q + + + ++E+ GV +++ A + AQ ++ Sbjct: 69 QLVVDNHEISVYQCKEPKQIPWRAVGSPYVVESTGVYLSIQAASDHISAGAQRVVISAPS 128 Query: 264 QDLHLTSATFGK 275 D + + Sbjct: 129 PDAPMFVMGVNE 140 >4RDI-A nrPDB Length = 288 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 11/54 (20%), Positives = 23/54 (42%) Query: 145 PITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKL 198 T L+ Q + ++ ++G G +G A + G ++T ID+ + Sbjct: 34 GGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCV 87 >6HNS-A nrPDB Length = 454 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 15/29 (51%), Positives = 15/29 (51%), Gaps = 3/29 (10%) Query: 161 NKNVIIIGAGTIGLL---AIQCAVALGAK 186 N V IIGAG GL A Q A A GA Sbjct: 2 NTRVAIIGAGPCGLAQLRAFQSAAAKGAA 30 >6DLL-A nrPDB Length = 398 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 11/27 (40%), Positives = 13/27 (48%) Query: 164 VIIIGAGTIGLLAIQCAVALGAKSVTA 190 V IIGAG GLL Q G ++ Sbjct: 8 VAIIGAGPSGLLLGQLLHKAGIDNIIV 34 >5JE5-A nrPDB Length = 247 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 14/53 (26%), Positives = 23/53 (43%), Gaps = 2/53 (3%) Query: 151 HAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKS 203 FH+ K+V+ + G G + GA V +DIS + + LA+ Sbjct: 32 TIFHMIGDVSGKSVLDLACG-FGFFGREIYR-RGAAKVVGVDISEKMIELARE 82 >6APH-A nrPDB Length = 445 Score = 30.4 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 29/192 (15%), Positives = 55/192 (28%), Gaps = 17/192 (8%) Query: 158 GCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSA 217 K V++ G G +G G VT +I A AM+ + ++ Sbjct: 223 MLAGKRVVVCGFGDVGKGTAASFRGAG-SIVTVTEIDPICALQA----AMEGYEVKQLDT 277 Query: 218 PQMQSVLRELRFNQLILETAGVPQTVE-LAVEIAGPHAQLALVGTLHQDLHLTSATFGKI 276 + +I+ T G V E + +G ++ + Sbjct: 278 V--------VDNADIIITTTGNFGIVRGEHFEKMKDKTIVCNIGHFDNEIDMAWLNKNHG 329 Query: 277 LRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDI--A 334 K + + Y+ RL+ + P SF + A ++ Sbjct: 330 ATK-VEIKPQVDKYNVNGNDIIILAEGRLVNLGCATGHPSFVMSNSFSNQTLAQIELWVH 388 Query: 335 RNAMPGKVLLIP 346 + KV +P Sbjct: 389 SDKYENKVYTLP 400 >5YSS-A nrPDB Length = 256 Score = 30.0 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 36/89 (40%), Gaps = 9/89 (10%) Query: 161 NKNVIIIGA-GTIGLLAIQCAVALGAKSVT--AIDISSEKLALAKSFGAMQTFNSSEMSA 217 K ++ G+ IGL Q GA + D+ + K A+A +G ++ +++S Sbjct: 5 GKTALVTGSTSGIGLGIAQVLAQAGATLILNGFGDVDAAKDAVA-QYGKTPGYHGADLSD 63 Query: 218 PQMQSVL-----RELRFNQLILETAGVPQ 241 + + E +++ AG+ Sbjct: 64 EAQIADMMRYAESEFGGVDILINNAGIQH 92 >5BXY-A nrPDB Length = 158 Score = 30.0 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 20/110 (18%), Positives = 36/110 (32%), Gaps = 6/110 (5%) Query: 151 HAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSV---TAIDISSEKLALAKSFGAM 207 LA E + +G+G G + I+ A GA+ V D+ + AK G Sbjct: 15 RMLELADVDETDVLYDLGSGD-GRIVIRAARTHGARGVGIEIDPDLVKKARKNAKEAGVA 73 Query: 208 QTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLA 257 + ++ + E L L + + + E P + Sbjct: 74 DLVEFRQGDL--FEADISEATVVTLYLLPSVNQKLRPILFEQLSPGTPVV 121 >1HL3-A nrPDB Length = 358 Score = 30.0 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 9/29 (31%), Positives = 12/29 (41%) Query: 156 AQGCENKNVIIIGAGTIGLLAIQCAVALG 184 A + + IIG G +G A A G Sbjct: 166 AARIRGETLGIIGLGRVGQAVALRAKAFG 194 >4DYD-A nrPDB Length = 283 Score = 30.0 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 29/130 (22%), Positives = 51/130 (39%), Gaps = 19/130 (14%) Query: 162 KNVIIIGAGTIGL-LAIQCAVALGAKSVTAIDISSEKLALAKS-------------FGAM 207 NV ++G G +G +A Q A A VTA DI+++ L AK GA Sbjct: 5 TNVTVLGTGVLGSQIAFQTAFHGFA--VTAYDINTDALDAAKKRFEGLAAVYEKEVAGAA 62 Query: 208 QTFNSSEMSAPQMQSVLRE-LRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDL 266 + + L + ++ L++E P++++L +I +LA T+ Sbjct: 63 DGAAQKALGGIRYSDDLAQAVKDADLVIEAV--PESLDLKRDIYTKLGELAPAKTIFATN 120 Query: 267 HLTSATFGKI 276 T + Sbjct: 121 SSTLLPSDLV 130 >3X2F-A nrPDB Length = 411 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 17/92 (18%), Positives = 28/92 (30%), Gaps = 13/92 (14%) Query: 158 GCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFG------------ 205 KNV++ G G G A LGA V ++ K A G Sbjct: 194 LVAGKNVVVAGYGWCGRGIALRAAGLGA-RVIVTEVDPVKAVEAIMDGFTVMPMKEAVKI 252 Query: 206 AMQTFNSSEMSAPQMQSVLRELRFNQLILETA 237 A +S + + + L+ ++ Sbjct: 253 ADFVITASGNTDVLSKEDILSLKDGAVLANAG 284 >4XTI-A nrPDB Length = 413 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 19/107 (17%), Positives = 41/107 (38%), Gaps = 4/107 (3%) Query: 170 GTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTF-NSSEMSAPQMQSVLRELR 228 G + + L ++ ID ++LA+ G +SS+ ++ ++++ ++ Sbjct: 126 GPLASKSADTKQLLCGAAIGTIDADRQRLAMLVEAGLDVVVLDSSQGNSVFQINMIKWIK 185 Query: 229 --FNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATF 273 F L + AG T E A + A +G + +T Sbjct: 186 ETFPDLQV-IAGNVVTREQAASLIHAGADGLRIGMGSGSICITQEVM 231 >1I6N-A nrPDB Length = 278 Score = 30.0 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 28/156 (17%), Positives = 52/156 (33%), Gaps = 20/156 (12%) Query: 180 AVALGAKSVTAID-ISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAG 238 LG K V A+ ++ +K+ + S + S + E ++ LE G Sbjct: 93 CKTLGVKYVVAVPLVTEQKIVK-------EEIKKSSVDVLTELSDIAEPYGVKIALEFVG 145 Query: 239 VPQ----TVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNY---S 291 PQ T E A EI + VG + H + K+ ++ + + Sbjct: 146 HPQCTVNTFEQAYEIVNTVNR-DNVGLVLDSFHFHAMGSNIESLKQADGKKIFIYHIDDT 204 Query: 292 SPWPGQEWETASR-LLTERKLSLEPLIAHRGSFESF 326 +P R + + L+ AH + + Sbjct: 205 EDFPIGFLTDEDRVWPGQGAIDLD---AHLSALKEI 237 >4K28-A nrPDB Length = 269 Score = 29.6 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 15/47 (31%), Positives = 22/47 (46%), Gaps = 2/47 (4%) Query: 152 AFHLAQGCENKNVIIIGAGTIGLLAIQCAVA-LGAKSVTAIDISSEK 197 A K ++IG G +G AI A+A G S+T D S+ + Sbjct: 116 AHKHGFEPAGKRALVIGCGGVG-SAIAYALAEAGIASITLCDPSTAR 161 >1YOV-B nrPDB Length = 444 Score = 29.6 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 17/32 (53%) Query: 163 NVIIIGAGTIGLLAIQCAVALGAKSVTAIDIS 194 V++IGAG +G ++ G + + ID+ Sbjct: 52 KVLVIGAGGLGCELLKNLALSGFRQIHVIDMD 83 >3F9I-A nrPDB Length = 249 Score = 29.6 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 21/91 (23%), Positives = 31/91 (34%), Gaps = 3/91 (3%) Query: 161 NKNVIIIGAG-TIGLLAIQCAVALGAKSVTAIDISSEKLA-LAKSFGAMQTFNSSEMSAP 218 K +I GA IG + LG V + EKL L + T ++ Sbjct: 14 GKTSLITGASSGIGSAIARLLHKLG-SKVIISGSNEEKLKSLGNALKDNYTIEVCNLANK 72 Query: 219 QMQSVLRELRFNQLILETAGVPQTVELAVEI 249 + S L N IL + LA+ + Sbjct: 73 EECSNLISKTSNLDILVCNAGITSDTLAIRM 103 >2BHS-A nrPDB Length = 303 Score = 29.6 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 32/189 (16%), Positives = 65/189 (34%), Gaps = 13/189 (6%) Query: 128 VFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAK- 186 L + P +++ + A + +I +G G+ A G + Sbjct: 28 WLKLEGNNPAGSVKDRAALSMIVEAEKRGEIKPGDVLIEATSGNTGIALAMIAALKGYRM 87 Query: 187 SVTAID-ISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLREL--RFNQLILETAGVPQTV 243 + D +S E+ A +++GA + E + + E+ R +L+ P Sbjct: 88 KLLMPDNMSQERRAAMRAYGAELILVTKEQGMEGARDLALEMANRGEGKLLDQFNNPDNP 147 Query: 244 ELAVEIAGP------HAQLA-LVGTLHQDLHLTSAT-FGKILRKELTVIGSWMNYSSPWP 295 GP ++ V ++ +T + F + K +T++G S P Sbjct: 148 YAHYTTTGPEIWQQTGGRITHFVSSMGTTGTITGVSRFMREQSKPVTIVGLQPEEGSSIP 207 Query: 296 G-QEWETAS 303 G + W T Sbjct: 208 GIRRWPTEY 216 >2ZJ1-A nrPDB Length = 495 Score = 29.6 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 18/109 (16%), Positives = 37/109 (33%), Gaps = 14/109 (12%) Query: 161 NKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQM 220 K V+I G G +G + GA V+ +I A G + Sbjct: 275 GKKVLICGYGDVGKGCAEAMKGQGA-RVSVTEIDPINALQAMMEGFDVV---------TV 324 Query: 221 QSVLRELRFNQLILETAGVPQTVELA-VEIAGPHAQLALVGTLHQDLHL 268 + + + +++ G + L ++ HA L +G ++ + Sbjct: 325 EEAIGD---ADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDM 370 >2NVU-B nrPDB Length = 805 Score = 29.6 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 17/32 (53%) Query: 163 NVIIIGAGTIGLLAIQCAVALGAKSVTAIDIS 194 V++IGAG +G ++ G + + ID+ Sbjct: 413 KVLVIGAGGLGCELLKNLALSGFRQIHVIDMD 444 >4XGI-A nrPDB Length = 436 Score = 29.6 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 20/56 (35%), Gaps = 1/56 (1%) Query: 138 EDGAFIEPITVGLHAFHLAQGC-ENKNVIIIGAGTIGLLAIQCAVALGAKSVTAID 192 ++ VG A E + + G G +G +A + GAK + D Sbjct: 207 KEATGRGVFVVGCEAAKKKGVEIEGARIAVQGFGNVGGIAAKLFQEAGAKVIAVQD 262 >3NJ4-A nrPDB Length = 435 Score = 29.6 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 13/76 (17%), Positives = 23/76 (30%), Gaps = 5/76 (6%) Query: 160 ENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISS-EKLALAKSFGAMQTFNSSEMSAP 218 K ++ G G +G Q GA V +I L A + + + Sbjct: 215 AGKVAVVAGYGDVGKGCAQALRGFGA-RVIITEIDPINALQAAMEG---YEVTTMDEACQ 270 Query: 219 QMQSVLRELRFNQLIL 234 + + +IL Sbjct: 271 EGNIFVTTTGCIDIIL 286 >3DC2-A nrPDB Length = 529 Score = 29.6 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 14/29 (48%) Query: 161 NKNVIIIGAGTIGLLAIQCAVALGAKSVT 189 K V ++G G IG L Q A GA V Sbjct: 142 GKTVGVVGLGRIGQLVAQRIAAFGAYVVA 170 >2AVN-A nrPDB Length = 260 Score = 29.6 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 10/69 (14%), Positives = 18/69 (26%), Gaps = 1/69 (1%) Query: 187 SVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRE-LRFNQLILETAGVPQTVEL 245 V +D S E L +A+ G + P L ++ + Sbjct: 78 EVVLVDPSKEMLEVAREKGVKNVVEAKAEDLPFPSGAFEAVLALGDVLSYVENKDKAFSE 137 Query: 246 AVEIAGPHA 254 + P Sbjct: 138 IRRVLVPDG 146 >1MV8-A nrPDB Length = 436 Score = 29.6 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 27/89 (30%), Gaps = 12/89 (13%) Query: 163 NVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQS 222 + I G G +G + C A G V +D+SS K+ L G + Q Sbjct: 2 RISIFGLGYVGAVCAGCLSARG-HEVIGVDVSSTKIDLINQ-GKSPIVEPGLEALLQQGR 59 Query: 223 VLRELRF----------NQLILETAGVPQ 241 L + + G P Sbjct: 60 QTGRLSGTTDFKKAVLDSDVSFICVGTPS 88 >1LTH-T nrPDB Length = 319 Score = 29.6 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 11/40 (27%), Positives = 19/40 (47%), Gaps = 1/40 (2%) Query: 162 KNVIIIGAGTIGLLAIQCAVALG-AKSVTAIDISSEKLAL 200 + +IGAG +G A G A+ + DI+ E++ Sbjct: 8 TKLAVIGAGAVGSTLAFAAAQRGIAREIVLEDIAKERVEA 47 >3GDF-A nrPDB Length = 267 Score = 29.2 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 20/119 (16%), Positives = 38/119 (31%), Gaps = 16/119 (13%) Query: 161 NKNVIIIGAG---TIGLLAIQCAVALGAKSVTAIDISSE-KLALAKSFGAMQTFNSS--- 213 K V++ GA +G+ A + +GA ++ K + Sbjct: 20 GKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKTYGIKAKAYK 79 Query: 214 ------EMSAPQMQSVLRELRFNQLILETAGVPQ---TVELAVEIAGPHAQLALVGTLH 263 E ++ V+ + + AG ++ +VE Q+ L GT H Sbjct: 80 CQVDSYESCEKLVKDVVADFGQIDAFIANAGATADSGILDGSVEAWNHVVQVDLNGTFH 138 >3JTM-A nrPDB Length = 351 Score = 29.2 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 22/90 (24%), Positives = 31/90 (34%), Gaps = 5/90 (5%) Query: 153 FHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNS 212 + A E K + +GAG IG L +Q G ++ D L K GA + Sbjct: 156 AYRAYDLEGKTIGTVGAGRIGKLLLQRLKPFG-CNLLYHDRLQMAPELEKETGAKFVEDL 214 Query: 213 SEM----SAPQMQSVLRELRFNQLILETAG 238 +EM + L E E G Sbjct: 215 NEMLPKCDVIVINMPLTEKTRGMFNKELIG 244 >4Z87-A nrPDB Length = 525 Score = 29.2 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 38/95 (40%), Gaps = 5/95 (5%) Query: 182 ALGAKSVTAIDISSEKLALAKSFGAMQTF-NSSEMSAPQMQSVLRELR--FNQLILETAG 238 GA + ID ++LA+ G +SS+ ++ ++++ ++ F L + AG Sbjct: 251 LCGAA-IGTIDADRQRLAMLVEAGLDVVVLDSSQGNSVFQINMIKWIKETFPDLQV-IAG 308 Query: 239 VPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATF 273 T E A + A +G + +T Sbjct: 309 NVVTREQAASLIHAGADGLRIGMGSGSICITQEVM 343 >3H9U-A nrPDB Length = 436 Score = 29.2 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 11/76 (14%), Positives = 19/76 (25%), Gaps = 6/76 (7%) Query: 160 ENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISS-EKLALAKSFGAMQTFNSSEMSAP 218 K + G G +G GA V ++ L A + Sbjct: 210 AGKTACVCGYGDVGKGCAAALRGFGA-RVVVTEVDPINALQAAMEGYQVLLV----EDVV 264 Query: 219 QMQSVLRELRFNQLIL 234 + + N I+ Sbjct: 265 EEAHIFVTTTGNDDII 280 >5NMX-A nrPDB Length = 425 Score = 29.2 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 8/23 (34%), Positives = 12/23 (52%) Query: 162 KNVIIIGAGTIGLLAIQCAVALG 184 + V ++GAG GL A + G Sbjct: 2 RRVAVLGAGPSGLTAARYLKQAG 24 >4E4T-A nrPDB Length = 419 Score = 29.2 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 20/126 (15%), Positives = 39/126 (30%), Gaps = 13/126 (10%) Query: 139 DGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKL 198 + P ++ ++ + ++G G +G + A ++G V +D Sbjct: 13 EAQTQGPGSMTATPDSVSPILPGAWLGMVGGGQLGRMFCFAAQSMG-YRVAVLDPDP--- 68 Query: 199 ALAKSFGAMQTFNSSEMSAPQMQSVLRELRF--NQLILETAGVPQT---VELAVEIAGPH 253 A GA + +A ++ L EL + E VP P Sbjct: 69 --ASPAGA--VADRHLRAAYDDEAALAELAGLCEAVSTEFENVPAASLDFLARTTFVAPA 124 Query: 254 AQLALV 259 + V Sbjct: 125 GRCVAV 130 >4GCM-A nrPDB Length = 312 Score = 29.2 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 32/190 (16%), Positives = 63/190 (33%), Gaps = 39/190 (20%) Query: 164 VIIIGAGTIGLLAIQCAVALGAKS--------------------------VTAIDISSEK 197 + IIGAG G+ A A K+ +T D+S++ Sbjct: 9 IAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKM 68 Query: 198 LALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQ------LILETAGVPQ---TVELAVE 248 AK FGA + ++ + + + + + F ++ G V E Sbjct: 69 FEHAKKFGA--VYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQE 126 Query: 249 IAGPHAQLALV--GTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLL 306 + G V G ++ L G +E T + + + + ++ A R+L Sbjct: 127 LGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRIL 186 Query: 307 TERKLSLEPL 316 +R + + Sbjct: 187 QDRAFKNDKI 196 >5IJZ-A nrPDB Length = 447 Score = 29.2 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 35/91 (38%), Gaps = 10/91 (10%) Query: 161 NKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQM 220 + +I+ G+G + AI+ A LGA + D S G + T N +++ + Sbjct: 233 GQKIIVSGSGNVATYAIEKAQELGATVIGFSDSS----------GWVHTPNGVDVAKLRE 282 Query: 221 QSVLRELRFNQLILETAGVPQTVELAVEIAG 251 +R R + E G + ++ Sbjct: 283 IKEVRRARVSVYADEVEGATYHTDGSIWDLK 313 >4WJI-A nrPDB Length = 293 Score = 29.2 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 21/115 (18%), Positives = 37/115 (32%), Gaps = 13/115 (11%) Query: 162 KNVIIIGAGTIGLLAIQCAVALG-AKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQM 220 + + +IG G IG + A ++ S L A G + Sbjct: 5 QTIALIGIGLIGSSIARDIREKQLAGTIVVTTRSEATLKRAGELG---------LGDRYT 55 Query: 221 QSVLRELRFNQLILETAGVPQTVELAVEI---AGPHAQLALVGTLHQDLHLTSAT 272 S + L++ + V + +A EI P A + VG+ + A Sbjct: 56 LSAAEAVEGADLVVVSVPVGASGAVAAEIAAHLKPGAIVTDVGSTKGSVIAQMAP 110 >5TQV-A nrPDB Length = 233 Score = 29.2 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 17/94 (18%), Positives = 32/94 (34%), Gaps = 3/94 (3%) Query: 162 KNVIIIGAG-TIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAM-QTFNSSEMSAPQ 219 K V+I+GA +G ++ G +V A LA ++ GA + ++ Sbjct: 10 KTVLIVGASRGLGREFVRQYQRDG-WNVIATARDDASLAALRALGAHAHALDITQPEQIA 68 Query: 220 MQSVLRELRFNQLILETAGVPQTVELAVEIAGPH 253 + + + +GV VE Sbjct: 69 ALGWKLDGERLDVAVVVSGVYGPRTEGVETIASD 102 >1DOD-A nrPDB Length = 394 Score = 29.2 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 12/26 (46%), Positives = 13/26 (50%) Query: 164 VIIIGAGTIGLLAIQCAVALGAKSVT 189 V IIGAG GLL Q G +V Sbjct: 5 VAIIGAGPSGLLLGQLLHKAGIDNVI 30 >2HAE-A nrPDB Length = 386 Score = 28.8 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 17/31 (54%) Query: 163 NVIIIGAGTIGLLAIQCAVALGAKSVTAIDI 193 V++ G G G ++ + LG K+V A+D Sbjct: 184 KVVVNGIGAAGYNIVKFLLDLGVKNVVAVDR 214 >5B37-A nrPDB Length = 361 Score = 28.8 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 22/78 (28%), Gaps = 6/78 (7%) Query: 135 MPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSV--TAID 192 PI I + + ++ + V + G G +G L V D Sbjct: 143 APITSLGVFLGIKAAVESRWQSKRLDGMKVAVQGLGNVGKN---LCRHLHEHDVQLFVSD 199 Query: 193 ISSEKLALAKSF-GAMQT 209 + K K GA Sbjct: 200 VDPIKAEEVKRLFGATVV 217 >2AS0-A nrPDB Length = 396 Score = 28.8 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 13/31 (41%), Positives = 15/31 (48%), Gaps = 1/31 (3%) Query: 173 GLLAIQCAVALGAKSVTAIDISSEKLALAKS 203 G AI A+A GA V ID S + AK Sbjct: 229 GGFAIHAAIA-GADEVIGIDKSPRAIETAKE 258 >5GVX-A nrPDB Length = 430 Score = 28.8 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 10/71 (14%), Positives = 20/71 (28%), Gaps = 5/71 (7%) Query: 140 GAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLA 199 G F + V + A + V++ + A G + +D + Sbjct: 80 GVFGSGLDVPIVAAGRLAVRPGRCVVVSAH----SAGVTAARESGFALIIGVDRT-GCRD 134 Query: 200 LAKSFGAMQTF 210 + GA Sbjct: 135 ALRRDGADTVV 145 >1WY7-A nrPDB Length = 207 Score = 28.8 bits (63), Expect = 3.9, Method: Composition-based stats. Identities = 16/51 (31%), Positives = 26/51 (50%), Gaps = 2/51 (3%) Query: 153 FHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKS 203 + E K V +GAGT G+L+ A+ LGAK V +++ E + + Sbjct: 42 AYSLGDIEGKVVADLGAGT-GVLSY-GALLLGAKEVICVEVDKEAVDVLIE 90 >3VAZ-P nrPDB Length = 344 Score = 28.4 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 30/157 (19%), Positives = 48/157 (30%), Gaps = 26/157 (16%) Query: 163 NVIIIGAGTIGLLA---IQCAVALGAKSVTAIDI-SSEKLALAKSF--------GAMQTF 210 V I G G IG LA IQ G + V D+ + LA + G ++ Sbjct: 12 KVAINGFGRIGRLAFRRIQ--EVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVV 69 Query: 211 N---------SSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGT 261 + S P + + ++LE G + A A+ L+ Sbjct: 70 DGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISA 129 Query: 262 LHQDLHLTSA---TFGKILRKELTVIGSWMNYSSPWP 295 T ++ E V G+ +S P Sbjct: 130 PATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAP 166 >3OH0-A nrPDB Length = 641 Score = 28.4 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 16/91 (17%), Positives = 27/91 (29%), Gaps = 10/91 (10%) Query: 93 PECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAFIEPI------ 146 EC + + + GG A+YI + + ++ I Sbjct: 35 DECNERQIALLTDLYMFSNMYPGGVAQYIRNGHELLARESEEVDFAALEMPPLIFEAPSL 94 Query: 147 ---TVGLHAFHLAQGCEN-KNVIIIGAGTIG 173 T A A K V ++ AG +G Sbjct: 95 HRRTAERTALENAGTAMLCKTVFVLVAGGLG 125 >2HQM-A nrPDB Length = 479 Score = 28.4 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 36/239 (15%), Positives = 74/239 (30%), Gaps = 29/239 (12%) Query: 118 AEYIVVKRKNVFALPTDMP-IEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLA 176 A +I+V P ++P E G + + K V+++GAG IG+ Sbjct: 149 ANHILVATGGKAIFPENIPGFELGTDSDGF--------FRLEEQPKKVVVVGAGYIGIEL 200 Query: 177 IQCAVALGAKS--VTAIDISSEKLALAKSFGAM-----QTFNSSEMSAPQMQSVLRELRF 229 LG+++ V + K + N ++S E Sbjct: 201 AGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDK 260 Query: 230 NQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTV------ 283 ++ + + V+ + G + L G +++ + + +I+ E Sbjct: 261 LKIHMNDSKSIDDVDELIWTIGRKSHL---GMGSENVGIKLNSHDQIIADEYQNTNVPNI 317 Query: 284 --IGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPG 340 +G + P A R L+ R E + +E+ + G Sbjct: 318 YSLGDVVGKVELTPVAI--AAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPEAGSIG 374 >2JC3-A nrPDB Length = 303 Score = 28.4 bits (62), Expect = 4.8, Method: Composition-based stats. Identities = 15/97 (15%), Positives = 33/97 (34%), Gaps = 2/97 (2%) Query: 128 VFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAK- 186 L + P +++ + A + +I +G G+ A G + Sbjct: 28 WVKLEGNNPAGSVKDRAALSMIVEAEKRGEIKPGDVLIEATSGNTGIALAMIAALKGYRM 87 Query: 187 SVTAID-ISSEKLALAKSFGAMQTFNSSEMSAPQMQS 222 + D +S E+ A +++GA + E + Sbjct: 88 KLLMPDNMSQERRAAMRAYGAELILVTKEQGMEGARD 124 >1CP2-A nrPDB Length = 269 Score = 28.4 bits (62), Expect = 4.8, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 31/93 (33%), Gaps = 11/93 (11%) Query: 164 VIIIGAGTIGLLA-----IQCAVALGAKSVTAIDISSEKLALAKSFGA---MQTFN--SS 213 V I G G IG A+G K++ + + + G + Sbjct: 4 VAIYGKGGIGKSTTTQNLTSGLHAMG-KTIMVVGCDPKADSTRLLLGGLAQKSVLDTLRE 62 Query: 214 EMSAPQMQSVLRELRFNQLILETAGVPQTVELA 246 E ++ S+L+E +E+ G V A Sbjct: 63 EGEDVELDSILKEGYGGIRCVESGGPEPGVGCA 95 >2YQ5-A nrPDB Length = 343 Score = 28.4 bits (62), Expect = 4.9, Method: Composition-based stats. Identities = 13/31 (41%), Positives = 17/31 (54%), Gaps = 1/31 (3%) Query: 163 NVIIIGAGTIGLLAIQCAVALGAKSVTAIDI 193 V +IG G IG + A+GAK V A D+ Sbjct: 150 TVGLIGVGHIGSAVAEIFSAMGAK-VIAYDV 179 >4YRY-B nrPDB Length = 468 Score = 28.4 bits (62), Expect = 5.0, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 23/46 (50%) Query: 158 GCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKS 203 K V +IGAG + A + A+ LGA+ V + +E+ A+ Sbjct: 276 IRVGKKVAVIGAGNTAMDAARSALRLGAEKVYIVYRRTEREMPARR 321 >5XW3-A nrPDB Length = 315 Score = 28.4 bits (62), Expect = 5.1, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 27/78 (34%), Gaps = 2/78 (2%) Query: 152 AFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAI--DISSEKLALAKSFGAMQT 209 A E +I AG G+ A+ + + + S EK L K+ GA Sbjct: 55 ALEKGLVTEGGTIIEPTAGNTGIGLALAALQHDLRVIVCVPEKFSIEKQELMKALGATVV 114 Query: 210 FNSSEMSAPQMQSVLREL 227 +E + +EL Sbjct: 115 HTPTEQGMTGAIAKAKEL 132 >4P4L-A nrPDB Length = 277 Score = 28.4 bits (62), Expect = 5.1, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 19/41 (46%) Query: 165 IIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFG 205 +++G+G A+ LG +T + +S+K A G Sbjct: 121 LVLGSGGTAPAAVVGLAELGVTDITVVARNSDKAARLVDLG 161 >3OC4-A nrPDB Length = 452 Score = 28.4 bits (62), Expect = 5.2, Method: Composition-based stats. Identities = 9/16 (56%), Positives = 12/16 (75%) Query: 162 KNVIIIGAGTIGLLAI 177 + V +IGAG IG+ AI Sbjct: 148 QTVAVIGAGPIGMEAI 163 >4PRK-A nrPDB Length = 336 Score = 28.0 bits (61), Expect = 5.4, Method: Composition-based stats. Identities = 15/33 (45%), Positives = 19/33 (57%), Gaps = 1/33 (3%) Query: 161 NKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDI 193 NK + +IG G IG Q A+GAK V A D+ Sbjct: 146 NKTIGLIGVGHIGSAVAQIFSAMGAK-VLAYDV 177 >3VZS-A nrPDB Length = 257 Score = 28.0 bits (61), Expect = 5.5, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 29/85 (34%), Gaps = 9/85 (10%) Query: 168 GAGTIGLLAIQCAVALGAKSVTAIDISSEK----LALAKSFGAMQTF---NSSEMS--AP 218 G G IG Q G + V +S + L K+ G N ++ Sbjct: 22 GMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGNVADWDSTKT 81 Query: 219 QMQSVLRELRFNQLILETAGVPQTV 243 V E+ +++ AG+ + V Sbjct: 82 AFDKVKSEVGEVDVLINNAGITRDV 106 >5FUB-A nrPDB Length = 337 Score = 28.0 bits (61), Expect = 5.5, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 16/52 (30%) Query: 167 IGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAP 218 G G I L A G +V A ++ L K G + A Sbjct: 53 CGTGVISLFCALLAKPAGVYAVEASSMAEHTEELVKQNGCDGVVTVFQERAE 104 >3OKC-A nrPDB Length = 394 Score = 28.0 bits (61), Expect = 5.6, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 21/74 (28%), Gaps = 6/74 (8%) Query: 124 KRKNVFALPTDMPIE-----DGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQ 178 + A + E + T + + E NV A + L+A Sbjct: 45 NAEEAHAYDKTLDYEVIRWPRSVMLPTPTTAHAMAEIIREREIDNVWFGAAAPLALMA-G 103 Query: 179 CAVALGAKSVTAID 192 A GA V A Sbjct: 104 TAKQAGASKVIAST 117 >3FG2-P nrPDB Length = 404 Score = 28.0 bits (61), Expect = 5.6, Method: Composition-based stats. Identities = 13/35 (37%), Positives = 20/35 (57%), Gaps = 1/35 (2%) Query: 162 KNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSE 196 K+V++IGAG IGL A A G V ++++ Sbjct: 143 KHVVVIGAGFIGLEFAATARAKGL-EVDVVELAPR 176 >4TN1-B nrPDB Length = 345 Score = 28.0 bits (61), Expect = 5.6, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 22/59 (37%) Query: 233 ILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYS 291 +E GV V L+ I ++ L G A +EL + G ++++ Sbjct: 244 AIEGFGVTIDVILSNGILREGDRIVLCGLEGPIKTNIRALLTPAPMRELRIKGQYIHHK 302 >4NCL-A nrPDB Length = 457 Score = 28.0 bits (61), Expect = 5.6, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 22/59 (37%) Query: 233 ILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYS 291 +E GV V L+ I ++ L G A +EL + G ++++ Sbjct: 244 AIEGFGVTIDVILSNGILREGDRIVLCGLEGPIKTNIRALLTPAPMRELRIKGQYIHHK 302 >3GG9-A nrPDB Length = 352 Score = 28.0 bits (61), Expect = 5.6, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 21/49 (42%) Query: 153 FHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALA 201 F + + + + + I G G IG L A G + +S++ A A Sbjct: 152 FGIGRVLKGQTLGIFGYGKIGQLVAGYGRAFGMNVLVWGRENSKERARA 200 >4N3G-A nrPDB Length = 603 Score = 28.0 bits (61), Expect = 5.6, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 22/59 (37%) Query: 233 ILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYS 291 +E GV V L+ I ++ L G A +EL + G ++++ Sbjct: 244 AIEGFGVTIDVILSNGILREGDRIVLCGLEGPIKTNIRALLTPAPMRELRIKGQYIHHK 302 >3R9U-A nrPDB Length = 315 Score = 28.0 bits (61), Expect = 5.8, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 14/29 (48%) Query: 164 VIIIGAGTIGLLAIQCAVALGAKSVTAID 192 V IIG G GL A A G K+V + Sbjct: 7 VAIIGGGPAGLSAGLYATRGGLKNVVMFE 35 >5HQN-A nrPDB Length = 473 Score = 28.0 bits (61), Expect = 5.9, Method: Composition-based stats. Identities = 16/99 (16%), Positives = 31/99 (31%), Gaps = 12/99 (12%) Query: 78 GDAVACVPLLPCFTC-PECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMP 136 GD V + +P C +Y A+Y+ G F + V +F + Sbjct: 261 GDKVHIIGHIPPGHCLKSWSWNYYKIIARYEN---TLAGQFFGHTHVDEFEIFYDEETLS 317 Query: 137 -IEDGAFIEPITV-------GLHAFHLAQGCENKNVIII 167 AF+ P G + + + +++ Sbjct: 318 RPLAVAFLAPSATTFINLNPGYRVYQIDGNYPGSSHVVL 356 >5FI9-A nrPDB Length = 538 Score = 28.0 bits (61), Expect = 5.9, Method: Composition-based stats. Identities = 16/99 (16%), Positives = 31/99 (31%), Gaps = 12/99 (12%) Query: 78 GDAVACVPLLPCFTC-PECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMP 136 GD V + +P C +Y A+Y+ G F + V +F + Sbjct: 342 GDKVHIIGHIPPGHCLKSWSWNYYKIIARYEN---TLAGQFFGHTHVDEFEIFYDEETLS 398 Query: 137 -IEDGAFIEPITV-------GLHAFHLAQGCENKNVIII 167 AF+ P G + + + +++ Sbjct: 399 RPLAVAFLAPSATTFINLNPGYRVYQIDGNYPGSSHVVL 437 >1L1F-A nrPDB Length = 505 Score = 28.0 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 8/41 (19%), Positives = 16/41 (39%), Gaps = 3/41 (7%) Query: 157 QGCEN---KNVIIIGAGTIGLLAIQCAVALGAKSVTAIDIS 194 K ++ G G +GL +++ GAK + + Sbjct: 241 GMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESD 281 >3FEO-A nrPDB Length = 437 Score = 28.0 bits (61), Expect = 6.2, Method: Composition-based stats. Identities = 6/23 (26%), Positives = 10/23 (43%) Query: 35 SGLCGSDLPRIFKNGAHYYPITL 57 +CGSD+ + A P+ Sbjct: 93 CNICGSDIHPVGWCAASGKPLVP 115 >1O8Q-A nrPDB Length = 167 Score = 28.0 bits (61), Expect = 6.2, Method: Composition-based stats. Identities = 26/126 (20%), Positives = 41/126 (32%), Gaps = 4/126 (3%) Query: 184 GAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQT- 242 G ++V+ +D SSEKL AK A + ++ LIL G T Sbjct: 27 GPRAVSVVDSSSEKLGGAKVV-ATAVVPDEVERIKDILQKWSDVDEMDLILTLGGTGFTP 85 Query: 243 VELAVEIAGPHAQLALVGTLHQDLH--LTSATFGKILRKELTVIGSWMNYSSPWPGQEWE 300 ++ E + G L + L F + R + GS + + P Sbjct: 86 RDVTPEATKKVIERETPGLLFVMMQEALKITPFAMLSRSAAGIRGSTLIINMPGNPNAVA 145 Query: 301 TASRLL 306 L Sbjct: 146 ECMEAL 151 >4COO-A nrPDB Length = 563 Score = 28.0 bits (61), Expect = 6.7, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 26/72 (36%), Gaps = 6/72 (8%) Query: 158 GCENKNVI--IIGAGTIGLLAIQCAVALGAKSVTAI--DISSEKLALAKSFGAMQTFNSS 213 +I G IGL A G + + + +SSEK+ + ++ GA + Sbjct: 158 LKPGDTIIEPTSGNTGIGLA--LAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPT 215 Query: 214 EMSAPQMQSVLR 225 +S + Sbjct: 216 NARFDSPESHVG 227 >2WWR-A nrPDB Length = 330 Score = 28.0 bits (61), Expect = 6.8, Method: Composition-based stats. Identities = 11/52 (21%), Positives = 14/52 (26%), Gaps = 1/52 (1%) Query: 162 KNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSS 213 V IIG G IG + G + + A F A Sbjct: 156 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQP-RPEEAAEFQAEFVSTPE 206 >1M54-A nrPDB Length = 363 Score = 27.7 bits (60), Expect = 7.0, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 26/72 (36%), Gaps = 6/72 (8%) Query: 158 GCENKNVI--IIGAGTIGLLAIQCAVALGAKSVTAI--DISSEKLALAKSFGAMQTFNSS 213 +I G IGL A G + + + +SSEK+ + ++ GA + Sbjct: 93 LKPGDTIIEPTSGNTGIGLA--LAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPT 150 Query: 214 EMSAPQMQSVLR 225 +S + Sbjct: 151 NARFDSPESHVG 162 >2R9Z-A nrPDB Length = 463 Score = 27.7 bits (60), Expect = 7.1, Method: Composition-based stats. Identities = 39/219 (17%), Positives = 66/219 (30%), Gaps = 30/219 (13%) Query: 155 LAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKL---------ALAKSFG 205 A + K V IIGAG IG+ + G VT + + L LA++ Sbjct: 160 FALQQQPKRVAIIGAGYIGIELAGLLRSFG-SEVTVVALEDRLLFQFDPLLSATLAENMH 218 Query: 206 A-------MQTFNSSEMSAPQMQSVLRELR---FNQLILETAG-VPQTVELAVEIAGPHA 254 A + E A V ++ ++ G P T +L +E AG Sbjct: 219 AQGIETHLEFAVAALERDAQGTTLVAQDGTRLEGFDSVIWAVGRAPNTRDLGLEAAGIEV 278 Query: 255 QLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLE 314 Q G + D + + G ++T + + E +ERKL + Sbjct: 279 Q--SNGMVPTDAYQNTNVPGVYALGDITGRDQLTPVAIAAGRRLAERLFDGQSERKLDYD 336 Query: 315 PLIAHRG---SFESF----AQAVRDIARNAMPGKVLLIP 346 + +A + + P Sbjct: 337 NIPTVVFAHPPLSKVGLSEPEARERLGDVLTVYETSFTP 375 >1VHC-A nrPDB Length = 224 Score = 27.7 bits (60), Expect = 7.2, Method: Composition-based stats. Identities = 30/155 (19%), Positives = 50/155 (32%), Gaps = 26/155 (16%) Query: 176 AIQCAVALGAKSVTAID--ISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLI 233 AI+ A + A +++E++ LAKS GA P++ + ++L F I Sbjct: 58 AIRLLRANRPDFLIAAGTVLTAEQVVLAKSSGADFVVTP--GLNPKIVKLCQDLNFP--I 113 Query: 234 LETAGVPQTVELAVEIA----------GPHAQLALVGTLHQDLHLTSATFGKILRKELTV 283 P +E+A+E+ + L L G I + Sbjct: 114 TPGVNNPMAIEIALEMGISAVKFFPAEASGGVKMIKALLGPYAQLQIMPTGGIGLHNIRD 173 Query: 284 I----------GSWMNYSSPWPGQEWETASRLLTE 308 GSW W+ RL+ E Sbjct: 174 YLAIPNIVACGGSWFVEKKLIQSNNWDEIGRLVRE 208 >3AOE-E nrPDB Length = 419 Score = 27.7 bits (60), Expect = 7.3, Method: Composition-based stats. Identities = 11/57 (19%), Positives = 18/57 (31%), Gaps = 1/57 (1%) Query: 138 EDGAFIEPITVGLHAFHLAQG-CENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDI 193 +D A + + V V++ G G +G A LG + V Sbjct: 194 DDAAGLGALLVLEALAKRRGLDLRGARVVVQGLGQVGAAVALHAERLGMRVVAVATS 250 >3TNL-A nrPDB Length = 315 Score = 27.7 bits (60), Expect = 7.4, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 32/91 (35%), Gaps = 8/91 (8%) Query: 138 EDGAFIEPITVGLHAFHLAQGCENKNVI-----IIGAGTIGLLAIQCAVALGAKSVTAID 192 +DG IT G + A ++I I GAG A G K ++ + Sbjct: 127 DDGVLTGHITDG-TGYMRALKEAGHDIIGKKMTICGAGGAATAICIQAALDGVKEISIFN 185 Query: 193 ISSEKLALAKSFGAMQTFNSSEMSAPQMQSV 223 + A A+ ++ NS Q+ + Sbjct: 186 RKDDFYANAEKT--VEKINSKTDCKAQLFDI 214 >4IZO-A nrPDB Length = 419 Score = 27.7 bits (60), Expect = 7.6, Method: Composition-based stats. Identities = 8/38 (21%), Positives = 15/38 (39%), Gaps = 1/38 (2%) Query: 158 GCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISS 195 + ++G G +G + A A+G V +D Sbjct: 32 ILPGAWLGMVGGGQLGRMFCFAAQAMG-YRVAVLDPDP 68 >2YVG-A nrPDB Length = 408 Score = 27.7 bits (60), Expect = 7.7, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 19/47 (40%), Gaps = 1/47 (2%) Query: 155 LAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALA 201 A ++I+G G IGL A G V+ ++ ++ A Sbjct: 139 QAGLRPQSRLLIVGGGVIGLELAATARTAGVH-VSLVETQPRLMSRA 184 >5MMS-A nrPDB Length = 408 Score = 27.7 bits (60), Expect = 7.7, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 23/61 (37%), Gaps = 6/61 (9%) Query: 158 GCENKNVI--IIGAGTIGLLAIQCAVALGAKSVTAI--DISSEKLALAKSFGAMQTFNSS 213 +I G IGL A G + + + +SSEK+ + ++ GA + Sbjct: 136 LKPGDTIIEPTSGNTGIGLA--LAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPT 193 Query: 214 E 214 Sbjct: 194 N 194 >1NVM-B nrPDB Length = 312 Score = 27.7 bits (60), Expect = 8.1, Method: Composition-based stats. Identities = 25/116 (21%), Positives = 42/116 (36%), Gaps = 11/116 (9%) Query: 163 NVIIIGAGTIG--LL--AIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAP 218 V IIG+G IG L+ ++ A L ++ ID +S+ LA A+ G T + Sbjct: 6 KVAIIGSGNIGTDLMIKVLRNAKYLEMGAMVGIDAASDGLARAQRMGVTTT-----YAGV 60 Query: 219 QMQSVLRELRFNQLILETAGVPQTV--ELAVEIAGPHAQLALVGTLHQDLHLTSAT 272 + L E + + V E + A P +L + + Sbjct: 61 EGLIKLPEFADIDFVFDATSASAHVQNEALLRQAKPGIRLIDLTPAAIGPYCVPVV 116 >6ABI-A nrPDB Length = 358 Score = 27.7 bits (60), Expect = 8.3, Method: Composition-based stats. Identities = 22/141 (15%), Positives = 42/141 (29%), Gaps = 11/141 (7%) Query: 186 KSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVEL 245 + DI K +GA F + + + + ++ A E Sbjct: 27 TKIIFFDIKDYDKEFFKKYGADYNFEMTFLKVRLTEETANLTKGYDVVCGFANDNINKET 86 Query: 246 AVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYS--SPWPGQEWETAS 303 +A +L L + A F + K++ + SP E+ Sbjct: 87 IDIMAENGIKL---------LAMRCAGFNNVSLKDVNERFKVVRVPAYSPHAIAEYTVGL 137 Query: 304 RLLTERKLSLEPLIAHRGSFE 324 L RK++ + G+F Sbjct: 138 ILAVNRKINKAYVRTREGNFS 158 >3JTJ-A nrPDB Length = 253 Score = 27.7 bits (60), Expect = 8.3, Method: Composition-based stats. Identities = 10/74 (13%), Positives = 25/74 (33%), Gaps = 2/74 (2%) Query: 160 ENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEM--SA 217 K + I + + ++ A+A GA V + + ++ G ++ Sbjct: 20 PGKPLADIAGKPMVVHVMERALASGADRVIVATDHPDVVKAVEAAGGEVCLTRADHQSGT 79 Query: 218 PQMQSVLRELRFNQ 231 ++ V+ F Sbjct: 80 ERLAEVIEHYGFAD 93 >6DHM-A nrPDB Length = 582 Score = 27.7 bits (60), Expect = 8.4, Method: Composition-based stats. Identities = 9/41 (21%), Positives = 15/41 (36%), Gaps = 3/41 (7%) Query: 157 QGCEN---KNVIIIGAGTIGLLAIQCAVALGAKSVTAIDIS 194 K + G G +GL +++ GAK V + Sbjct: 318 GMTPGFGDKTFAVQGFGNVGLHSMRYLHRFGAKCVAVGESD 358 >2WUG-A nrPDB Length = 291 Score = 27.7 bits (60), Expect = 8.6, Method: Composition-based stats. Identities = 27/200 (13%), Positives = 60/200 (30%), Gaps = 29/200 (14%) Query: 153 FHLAQGCENKNVIIIGAGTIGLL--------AIQCAVALGAKSVTAIDI-----SSEKLA 199 +H A ++ V+++ G G A V A+D S ++ Sbjct: 28 YHEAGVGNDQTVVLLHGGGPGAASWTNFSRNIAVLARHF---HVLAVDQPGYGHSDKRAE 84 Query: 200 LAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALV 259 + FN A + L L+ G V A++ +L L+ Sbjct: 85 HGQ-------FNRYAAMALKGLFDQLGLGRVPLVGNALGGGTAVRFALDYPARAGRLVLM 137 Query: 260 GTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAH 319 G L+ F + + + + + + + ++ ++ L L+ Sbjct: 138 G----PGGLSINLFAPDPTEGVKRLSKFSVAPTRENLEAFLRV--MVYDKNLITPELVDQ 191 Query: 320 RGSFESFAQAVRDIARNAMP 339 R + S +++ Sbjct: 192 RFALASTPESLTATRAMGKS 211 >5MH6-A nrPDB Length = 308 Score = 27.7 bits (60), Expect = 8.8, Method: Composition-based stats. Identities = 10/29 (34%), Positives = 16/29 (55%) Query: 160 ENKNVIIIGAGTIGLLAIQCAVALGAKSV 188 + V ++G GT+G + A ALG + V Sbjct: 134 AGERVCVVGLGTLGRGVVDRAAALGMEVV 162 >1ZEJ-A nrPDB Length = 293 Score = 27.7 bits (60), Expect = 8.9, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 32/76 (42%), Gaps = 9/76 (11%) Query: 163 NVIIIGAGTIGL-LAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQ 221 V +IGAG +G +AI A V D+S + L A+ +S + Sbjct: 14 KVFVIGAGLMGRGIAIAIA---SKHEVVLQDVSEKALEAAREQ-----IPEELLSKIEFT 65 Query: 222 SVLRELRFNQLILETA 237 + L +++ +++E Sbjct: 66 TTLEKVKDCDIVMEAV 81 >5ZME-A nrPDB Length = 687 Score = 27.3 bits (59), Expect = 9.1, Method: Composition-based stats. Identities = 24/122 (19%), Positives = 41/122 (33%), Gaps = 17/122 (13%) Query: 154 HLAQGCENKNVIIIGAGTIG------LLAIQCAVALGAKSVTAIDIS---SEKLALAKSF 204 LA G + K ++I G G +G LA++ A A V + D + S+ LA S Sbjct: 5 ELAAGQQRKYIMISGKGGVGKTSLSASLAVKLAAAGHTTLVVSTDPAHSLSDSLAQDVSG 64 Query: 205 GAMQTFNSSEM-------SAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLA 257 G +++ + + E E AG P + Sbjct: 65 GRPVLLQGTDLPLWGLEIDPEEAKREFFEGSGAGQDGE-AGGPSAASQVSDFMNRMGMGF 123 Query: 258 LV 259 ++ Sbjct: 124 VI 125 >4ZGS-A nrPDB Length = 386 Score = 27.3 bits (59), Expect = 9.5, Method: Composition-based stats. Identities = 13/34 (38%), Positives = 17/34 (50%), Gaps = 1/34 (2%) Query: 162 KNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISS 195 K V ++G G IG A + +G K V A DI Sbjct: 179 KVVGVVGTGAIGQQAARILKGIGCK-VFAYDIKP 211 >1B26-A nrPDB Length = 416 Score = 27.3 bits (59), Expect = 9.5, Method: Composition-based stats. Identities = 33/201 (16%), Positives = 63/201 (31%), Gaps = 22/201 (10%) Query: 146 ITVGLHAFHLAQGCENK-NVIIIGAGTIGL-LAIQCAVALGAKSVTAIDI-----SSEKL 198 + GL A + K V + G G +G A+ + LG+K V D + E Sbjct: 195 VCAGL-AMDVLGIDPKKATVAVQGFGNVGQFAALLISQELGSKVVAVSDSRGGIYNPEGF 253 Query: 199 ALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAG---VPQTVELAVEIAGPHAQ 255 + + + E N+ +LE VP +E A+ Sbjct: 254 D------VEELIRYKKEHGTVVTYPKGERITNEELLELDVDILVPAALEGAIHAGNAERI 307 Query: 256 LALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEP 315 A + T + R+ + V+ + + + + L L+ Sbjct: 308 KAKAVVEGANGPTTPEADEILSRRGILVVPDILANAG-GVTVSYFEWVQDLQSFFWDLDQ 366 Query: 316 LIAHRGSFESFAQ-AVRDIAR 335 + R + E + A D+ + Sbjct: 367 V---RNALEKMMKGAFNDVMK 384 >1EUZ-A nrPDB Length = 419 Score = 27.3 bits (59), Expect = 9.6, Method: Composition-based stats. Identities = 14/89 (15%), Positives = 22/89 (24%), Gaps = 14/89 (15%) Query: 140 GAFIEPITVGLHAFHLAQG-CENKNVIIIGAGTIGLLAIQCAV-ALGAKSVTAIDISSEK 197 I A + K + + G G G + A LG V D Sbjct: 190 ATAQGAIFTIREAAKALGIDLKGKKIAVQGYGNAGYYTAKLAKEQLGMTVVAVSDSRGG- 248 Query: 198 LALAKSFGAMQTFNSSEMSAPQMQSVLRE 226 +N + ++ RE Sbjct: 249 -----------IYNPDGLDPDEVLKWKRE 266 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.316 0.140 0.387 Lambda K H 0.267 0.0427 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,572,415 Number of Sequences: 36641 Number of extensions: 605532 Number of successful extensions: 3416 Number of sequences better than 10.0: 366 Number of HSP's better than 10.0 without gapping: 298 Number of HSP's successfully gapped in prelim test: 190 Number of HSP's that attempted gapping in prelim test: 2471 Number of HSP's gapped (non-prelim): 535 length of query: 346 length of database: 10,336,785 effective HSP length: 98 effective length of query: 248 effective length of database: 6,745,967 effective search space: 1672999816 effective search space used: 1672999816 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 60 (27.7 bits)